# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- ABC1 PF03109.16 KFM22351.1 - 4.4e-31 107.5 0.0 7.4e-31 106.8 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Glutaredoxin PF00462.24 KFM22352.1 - 1.8e-18 66.5 0.0 2e-17 63.1 0.0 2.1 2 0 0 2 2 2 1 Glutaredoxin SH3BGR PF04908.15 KFM22352.1 - 0.0099 16.0 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein GST_N_3 PF13417.6 KFM22352.1 - 0.012 16.0 0.0 0.022 15.2 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain polyprenyl_synt PF00348.17 KFM22353.1 - 2.6e-74 249.5 0.0 3.1e-74 249.3 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 KFM22353.1 - 0.023 14.3 0.0 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Svs_4_5_6 PF17381.2 KFM22353.1 - 0.17 12.9 0.0 0.72 10.9 0.0 1.9 2 0 0 2 2 2 0 Seminal vesicle secretory proteins 4/5/6 XPA_C PF05181.12 KFM22354.1 - 2.1e-14 53.2 0.1 7.8e-08 32.2 0.0 2.3 2 0 0 2 2 2 2 XPA protein C-terminus F-box-like PF12937.7 KFM22354.1 - 0.00016 21.5 0.2 0.00033 20.5 0.2 1.5 1 0 0 1 1 1 1 F-box-like DUF1173 PF06666.11 KFM22354.1 - 0.003 16.6 0.2 0.0037 16.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1173) Ribo_biogen_C PF04034.13 KFM22354.1 - 0.0083 15.9 2.3 0.39 10.4 0.1 2.4 1 1 1 2 2 2 2 Ribosome biogenesis protein, C-terminal F-box_5 PF18511.1 KFM22354.1 - 0.0093 15.5 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 F-box F-box PF00646.33 KFM22354.1 - 0.014 15.3 0.1 0.025 14.5 0.1 1.5 1 0 0 1 1 1 0 F-box domain ATP-synt_B PF00430.18 KFM22355.1 - 1.2e-16 61.1 10.3 1.3e-16 60.9 10.3 1.0 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) Myb_Cef PF11831.8 KFM22355.1 - 0.011 15.3 1.0 0.011 15.3 1.0 1.4 1 1 0 1 1 1 0 pre-mRNA splicing factor component Phage_min_cap2 PF06152.11 KFM22355.1 - 0.013 14.5 2.0 0.015 14.3 2.0 1.0 1 0 0 1 1 1 0 Phage minor capsid protein 2 DUF4407 PF14362.6 KFM22355.1 - 0.021 14.2 12.5 0.029 13.7 12.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PIN_8 PF18476.1 KFM22355.1 - 0.048 13.5 4.3 0.062 13.1 4.3 1.1 1 0 0 1 1 1 0 PIN like domain DUF3584 PF12128.8 KFM22355.1 - 0.095 10.2 12.5 0.12 9.9 12.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) V-ATPase_G PF03179.15 KFM22355.1 - 0.11 13.0 11.1 0.16 12.5 11.1 1.2 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit Tho2 PF11262.8 KFM22355.1 - 0.17 11.1 2.7 0.2 10.8 2.7 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Fib_alpha PF08702.10 KFM22355.1 - 0.21 11.8 1.2 0.28 11.4 1.2 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Apolipoprotein PF01442.18 KFM22355.1 - 0.34 10.7 14.7 1.8 8.4 14.9 1.8 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Fez1 PF06818.15 KFM22355.1 - 0.4 11.1 6.0 0.52 10.7 6.0 1.0 1 0 0 1 1 1 0 Fez1 SRPRB PF09439.10 KFM22355.1 - 0.49 9.8 6.4 3.2 7.1 6.2 1.9 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit FUSC PF04632.12 KFM22355.1 - 0.95 7.9 3.6 1 7.8 3.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Baculo_PEP_C PF04513.12 KFM22355.1 - 1.1 9.3 3.5 6.8 6.7 3.4 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMPIT PF07851.13 KFM22355.1 - 1.2 8.3 2.7 1.6 7.9 2.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein OmpH PF03938.14 KFM22355.1 - 1.4 9.3 14.9 2.6 8.4 13.9 1.4 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Med25_SD1 PF11235.8 KFM22355.1 - 1.5 9.2 3.4 1.9 8.8 3.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 25 synapsin 1 PCRF PF03462.18 KFM22355.1 - 3.1 7.6 7.6 5.3 6.9 7.6 1.5 1 1 0 1 1 1 0 PCRF domain Phage_Mu_Gam PF07352.12 KFM22355.1 - 6.5 6.6 15.3 6.6 6.6 6.9 2.1 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein DUF1451 PF07295.11 KFM22355.1 - 7.4 6.6 9.8 36 4.4 9.6 1.8 1 1 0 1 1 1 0 Zinc-ribbon containing domain Methyltr_RsmB-F PF01189.17 KFM22356.1 - 3.2e-34 118.4 0.0 2.4e-33 115.5 0.0 2.1 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KFM22356.1 - 0.011 15.9 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Fasciclin PF02469.22 KFM22357.1 - 2.1e-10 40.9 0.0 3.5e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Fasciclin domain FinO_N PF12602.8 KFM22357.1 - 0.17 12.2 1.7 0.33 11.3 1.7 1.5 1 0 0 1 1 1 0 Fertility inhibition protein N terminal Thioredoxin PF00085.20 KFM22358.1 - 0.0064 16.5 0.0 0.0093 15.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Kisspeptin PF15152.6 KFM22359.1 - 4.8 8.0 28.8 65 4.4 1.8 5.5 1 1 3 4 4 4 0 Kisspeptin Pentapeptide_2 PF01469.18 KFM22360.1 - 0.025 14.5 9.3 0.031 14.2 9.3 1.1 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) Exostosin PF03016.15 KFM22361.1 - 1.8e-21 76.6 0.0 3.2e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Exostosin family DnaJ PF00226.31 KFM22363.1 - 1.2e-07 31.7 0.0 1.9e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain CSN8_PSD8_EIF3K PF10075.9 KFM22364.1 - 9e-15 54.9 1.1 4.3e-14 52.7 1.1 1.9 1 1 0 1 1 1 1 CSN8/PSMD8/EIF3K family YwqJ-deaminase PF14431.6 KFM22364.1 - 0.03 14.5 0.0 0.053 13.7 0.0 1.4 1 0 0 1 1 1 0 YwqJ-like deaminase AAA PF00004.29 KFM22365.1 - 3.7e-43 147.1 0.0 7.1e-43 146.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KFM22365.1 - 5.1e-10 39.2 0.1 1.9e-09 37.3 0.1 1.9 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KFM22365.1 - 3.8e-09 36.2 0.1 8.7e-09 35.1 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KFM22365.1 - 1.9e-07 31.6 0.0 0.00025 21.5 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 KFM22365.1 - 1.7e-06 28.3 0.0 1.2e-05 25.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KFM22365.1 - 5.5e-06 26.2 0.0 1.6e-05 24.7 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KFM22365.1 - 7.2e-06 26.0 0.1 0.00023 21.2 0.1 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KFM22365.1 - 0.00034 20.9 0.0 0.021 15.1 0.0 2.7 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 KFM22365.1 - 0.00046 19.4 0.0 0.0012 18.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 KFM22365.1 - 0.0014 19.2 0.0 0.0094 16.5 0.0 2.2 1 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KFM22365.1 - 0.0024 18.3 0.0 0.0048 17.3 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_7 PF12775.7 KFM22365.1 - 0.0032 17.0 0.0 0.0078 15.7 0.0 1.7 1 1 0 1 1 1 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 KFM22365.1 - 0.0048 16.3 0.1 0.0096 15.3 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 KFM22365.1 - 0.0052 16.0 0.0 0.0084 15.4 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 KFM22365.1 - 0.0055 16.5 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activat PF00158.26 KFM22365.1 - 0.007 16.1 0.0 0.035 13.8 0.0 2.1 1 1 1 2 2 2 1 Sigma-54 interaction domain Parvo_NS1 PF01057.17 KFM22365.1 - 0.0082 15.3 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_3 PF07726.11 KFM22365.1 - 0.013 15.4 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KFM22365.1 - 0.022 14.5 0.0 0.053 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KFM22365.1 - 0.025 14.6 0.0 0.049 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KFM22365.1 - 0.039 14.2 0.1 0.095 12.9 0.0 1.7 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.27 KFM22365.1 - 0.04 14.4 0.1 0.12 12.9 0.0 1.9 2 0 0 2 2 1 0 ABC transporter NACHT PF05729.12 KFM22365.1 - 0.04 13.8 0.1 0.11 12.4 0.0 1.7 2 0 0 2 2 1 0 NACHT domain TsaE PF02367.17 KFM22365.1 - 0.053 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 KFM22365.1 - 0.055 12.8 0.0 0.16 11.3 0.0 1.8 2 0 0 2 2 2 0 KaiC AAA_33 PF13671.6 KFM22365.1 - 0.062 13.4 0.2 0.14 12.3 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_11 PF13086.6 KFM22365.1 - 0.099 12.4 0.3 0.53 10.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KFM22365.1 - 0.1 12.3 0.0 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KFM22365.1 - 0.11 12.0 0.1 0.23 10.9 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein Thymidylate_kin PF02223.17 KFM22365.1 - 0.12 12.1 0.0 11 5.6 0.0 2.4 2 0 0 2 2 2 0 Thymidylate kinase ATPase_2 PF01637.18 KFM22365.1 - 0.12 12.3 0.0 0.37 10.7 0.0 1.9 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea PIF1 PF05970.14 KFM22365.1 - 0.19 10.8 0.0 0.32 10.1 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase AAA_25 PF13481.6 KFM22365.1 - 0.2 11.2 0.8 0.42 10.2 0.1 1.8 2 0 0 2 2 2 0 AAA domain Vpu PF00558.19 KFM22365.1 - 0.26 11.1 1.0 0.76 9.6 1.0 1.8 1 0 0 1 1 1 0 Vpu protein Pterin_bind PF00809.22 KFM22367.1 - 1.1e-31 110.4 0.3 1.4e-31 110.0 0.3 1.2 1 0 0 1 1 1 1 Pterin binding enzyme PRP38_assoc PF12871.7 KFM22368.1 - 0.0024 18.5 2.2 0.003 18.1 2.2 1.2 1 0 0 1 1 1 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Apelin PF15360.6 KFM22368.1 - 0.01 16.4 1.9 0.01 16.4 1.9 2.0 1 1 1 2 2 2 0 APJ endogenous ligand DUF4637 PF15470.6 KFM22368.1 - 0.019 14.7 0.2 0.022 14.5 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Herpes_UL37_1 PF03970.13 KFM22368.1 - 0.17 11.0 0.1 0.2 10.8 0.1 1.0 1 0 0 1 1 1 0 Herpesvirus UL37 tegument protein Macoilin PF09726.9 KFM22368.1 - 1.6 7.2 3.3 1.8 7.0 3.3 1.0 1 0 0 1 1 1 0 Macoilin family Rubredoxin PF00301.20 KFM22369.1 - 7.2e-06 25.9 10.3 0.00058 19.8 10.3 2.4 1 1 0 1 1 1 1 Rubredoxin zf-C2HC5 PF06221.13 KFM22369.1 - 0.0045 16.9 0.4 0.0098 15.9 0.4 1.5 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type DUF4096 PF13340.6 KFM22369.1 - 0.04 14.1 4.1 0.95 9.7 0.0 2.3 2 0 0 2 2 2 0 Putative transposase of IS4/5 family (DUF4096) TF_Zn_Ribbon PF08271.12 KFM22369.1 - 0.078 12.5 1.8 9.1 5.9 0.1 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding zinc_ribbon_9 PF14369.6 KFM22369.1 - 0.089 13.1 1.5 3.3 8.0 0.6 2.7 2 1 0 2 2 2 0 zinc-ribbon HypA PF01155.19 KFM22369.1 - 0.11 12.5 0.1 0.16 12.0 0.1 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA A2L_zn_ribbon PF08792.10 KFM22369.1 - 0.12 12.2 2.7 8.1 6.3 0.1 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-UBP PF02148.19 KFM22369.1 - 0.14 12.5 1.2 0.16 12.3 0.1 1.6 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein zf-HIT PF04438.16 KFM22369.1 - 0.78 9.7 5.0 0.83 9.6 0.1 2.3 2 0 0 2 2 2 0 HIT zinc finger Pkinase PF00069.25 KFM22370.1 - 3.3e-62 210.2 0.0 3.9e-62 210.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM22370.1 - 1.7e-29 102.9 0.0 2.4e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Steroid_dh PF02544.16 KFM22372.1 - 4e-24 85.3 0.0 7.4e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 KFM22372.1 - 0.00073 19.9 0.7 0.0021 18.4 0.7 1.8 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.12 KFM22372.1 - 0.023 14.2 0.7 0.043 13.3 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) Histone_H2A_C PF16211.5 KFM22374.1 - 9.7e-20 70.0 1.3 1.4e-19 69.5 1.3 1.3 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KFM22374.1 - 2.8e-14 53.6 0.0 3.2e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFM22374.1 - 1.2e-05 25.5 0.0 1.6e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Thiolase_N PF00108.23 KFM22377.1 - 0.054 12.8 0.0 0.062 12.7 0.0 1.0 1 0 0 1 1 1 0 Thiolase, N-terminal domain 2-Hacid_dh_C PF02826.19 KFM22378.1 - 9.4e-61 204.3 0.0 2.1e-60 203.1 0.0 1.7 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFM22378.1 - 7.3e-34 116.3 3.3 2.2e-33 114.8 1.8 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 KFM22378.1 - 3e-09 36.5 0.4 2.6e-08 33.5 0.1 2.8 3 0 0 3 3 3 1 ACT domain IlvN PF07991.12 KFM22378.1 - 0.00026 20.6 0.0 0.00072 19.2 0.0 1.8 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_2 PF03446.15 KFM22378.1 - 0.00049 20.3 2.8 0.0022 18.2 0.1 3.0 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 KFM22378.1 - 0.00081 19.5 0.2 0.0023 18.0 0.2 1.7 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ACT_7 PF13840.6 KFM22378.1 - 0.0031 17.3 0.0 0.013 15.3 0.0 2.1 1 0 0 1 1 1 1 ACT domain XdhC_C PF13478.6 KFM22378.1 - 0.0031 18.0 0.0 0.012 16.2 0.0 2.0 1 0 0 1 1 1 1 XdhC Rossmann domain ACT_4 PF13291.6 KFM22378.1 - 0.035 14.7 1.3 3.6 8.2 0.0 3.0 2 0 0 2 2 2 0 ACT domain DUF4585 PF15232.6 KFM22378.1 - 0.049 13.7 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4585) TPR_1 PF00515.28 KFM22380.1 - 1.1e-26 91.4 10.5 5e-07 29.3 0.1 6.6 6 1 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 KFM22380.1 - 2e-22 77.4 10.7 4.2e-06 26.5 0.0 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 KFM22380.1 - 1.6e-20 71.5 3.0 6.3e-06 26.0 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFM22380.1 - 1.7e-15 56.4 14.6 1.4e-05 25.5 0.1 5.3 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 KFM22380.1 - 1.4e-14 53.4 0.4 6e-08 32.2 0.2 3.8 2 1 1 3 3 3 2 TPR repeat TPR_7 PF13176.6 KFM22380.1 - 4.8e-14 51.3 11.7 0.0059 16.5 0.9 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFM22380.1 - 2.9e-13 50.2 21.2 2.5e-08 34.4 0.1 5.1 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 KFM22380.1 - 1.9e-12 47.5 9.5 0.0015 19.0 3.3 4.5 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFM22380.1 - 7.4e-12 45.4 21.2 0.00017 21.8 8.9 5.3 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_6 PF13174.6 KFM22380.1 - 1.1e-08 35.1 7.5 0.048 14.3 0.4 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFM22380.1 - 1.9e-08 34.1 8.3 0.017 15.5 0.0 6.1 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFM22380.1 - 7.2e-05 22.8 11.7 0.00016 21.7 0.3 4.1 1 1 1 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 KFM22380.1 - 0.00031 20.0 4.8 0.0044 16.3 0.2 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM22380.1 - 0.00057 20.1 12.8 0.0011 19.2 0.8 3.9 1 1 3 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KFM22380.1 - 0.00082 19.2 8.9 0.51 10.3 0.6 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat ChAPs PF09295.10 KFM22380.1 - 0.0058 15.7 0.0 2.4 7.0 0.0 2.5 1 1 2 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) SNAP PF14938.6 KFM22380.1 - 0.0078 15.7 2.9 0.029 13.8 0.8 2.3 2 1 0 2 2 2 1 Soluble NSF attachment protein, SNAP DUF1644 PF07800.12 KFM22380.1 - 0.036 14.1 0.1 0.25 11.4 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) TPR_4 PF07721.14 KFM22380.1 - 3.3 8.6 12.2 4.1 8.3 1.6 3.7 4 0 0 4 4 2 0 Tetratricopeptide repeat PAC3 PF10178.9 KFM22381.1 - 6.2e-13 48.7 0.0 8.2e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 KH_1 PF00013.29 KFM22382.1 - 1.7e-27 95.0 0.0 8.3e-12 44.8 0.0 3.2 3 0 0 3 3 3 2 KH domain KH_2 PF07650.17 KFM22382.1 - 3.6e-05 23.5 0.0 0.19 11.6 0.0 2.2 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 KFM22382.1 - 0.009 15.9 0.0 2.7 7.9 0.0 2.4 2 0 0 2 2 2 2 KH domain Sperm_Ag_HE2 PF05324.13 KFM22382.1 - 0.092 13.2 1.7 0.27 11.7 1.7 1.8 1 0 0 1 1 1 0 Sperm antigen HE2 DUF4460 PF14687.6 KFM22383.1 - 1.1e-15 57.7 0.1 1.3e-15 57.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4460) DnaJ PF00226.31 KFM22383.1 - 0.0057 16.8 0.1 0.0073 16.4 0.1 1.2 1 0 0 1 1 1 1 DnaJ domain TPR_9 PF13371.6 KFM22384.1 - 0.0019 18.3 10.1 0.0064 16.6 0.5 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat CS PF04969.16 KFM22384.1 - 0.059 14.4 0.0 0.097 13.7 0.0 1.3 1 0 0 1 1 1 0 CS domain Glyco_hydro_14 PF01373.17 KFM22385.1 - 1.1e-79 268.3 0.0 1e-55 189.4 0.0 4.0 2 2 1 3 3 3 3 Glycosyl hydrolase family 14 Ribosomal_S21 PF01165.20 KFM22386.1 - 5.3e-11 42.1 1.0 5.3e-11 42.1 1.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S21 AAA PF00004.29 KFM22390.1 - 2.3e-38 131.6 0.0 3.8e-38 130.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFM22390.1 - 6.7e-11 41.8 0.2 2.2e-10 40.2 0.2 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KFM22390.1 - 1.2e-06 29.1 3.0 2.7e-05 24.6 0.4 2.8 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KFM22390.1 - 4e-05 23.4 0.0 7.4e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 KFM22390.1 - 4.3e-05 23.2 0.6 0.028 14.0 0.0 2.7 1 1 1 2 2 2 2 AAA domain AAA_22 PF13401.6 KFM22390.1 - 7e-05 23.1 0.0 0.0006 20.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KFM22390.1 - 0.00012 22.1 0.0 0.00035 20.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KFM22390.1 - 0.00013 22.1 0.0 0.00023 21.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Vps4_C PF09336.10 KFM22390.1 - 0.00084 19.3 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain IstB_IS21 PF01695.17 KFM22390.1 - 0.0013 18.5 0.0 0.0023 17.7 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 KFM22390.1 - 0.0033 17.5 0.0 0.0058 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 KFM22390.1 - 0.0034 16.6 0.0 0.005 16.1 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain TniB PF05621.11 KFM22390.1 - 0.01 15.3 0.0 1.2 8.5 0.0 2.2 1 1 1 2 2 2 1 Bacterial TniB protein Mg_chelatase PF01078.21 KFM22390.1 - 0.01 15.2 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KFM22390.1 - 0.014 15.8 0.0 0.026 14.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase DUF815 PF05673.13 KFM22390.1 - 0.03 13.5 0.0 0.047 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 KFM22390.1 - 0.09 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KFM22390.1 - 0.099 12.6 0.0 0.27 11.2 0.0 1.8 1 1 1 2 2 2 0 NACHT domain TsaE PF02367.17 KFM22390.1 - 0.15 12.1 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DEAD PF00270.29 KFM22393.1 - 2.9e-37 128.1 0.0 4.4e-37 127.5 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KFM22393.1 - 0.00043 20.3 0.0 0.00075 19.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KFM22393.1 - 0.11 12.7 0.0 0.93 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain SOG2 PF10428.9 KFM22393.1 - 0.63 9.2 2.4 1.1 8.4 2.4 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Fcf1 PF04900.12 KFM22394.1 - 1.3e-10 41.5 0.3 1.9e-10 41.0 0.3 1.2 1 0 0 1 1 1 1 Fcf1 DUF3783 PF12646.7 KFM22395.1 - 5.8e-05 23.0 0.0 0.00015 21.6 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3783) AAA_lid_3 PF17862.1 KFM22396.1 - 4.8e-12 45.5 1.1 1.4e-11 44.0 1.1 1.7 1 1 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 KFM22396.1 - 0.00038 20.9 0.0 0.0006 20.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) COX5B PF01215.19 KFM22400.1 - 0.00016 21.4 0.0 0.00017 21.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Ribosomal_L6 PF00347.23 KFM22401.1 - 4e-34 117.1 5.5 1.2e-16 61.1 0.6 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 ADIP PF11559.8 KFM22403.1 - 1.8e-20 73.6 3.7 1.8e-20 73.6 3.7 2.1 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding DUF3847 PF12958.7 KFM22403.1 - 0.0081 16.2 3.5 0.0081 16.2 3.5 3.1 3 1 0 3 3 3 1 Protein of unknown function (DUF3847) ERM PF00769.19 KFM22403.1 - 0.012 15.5 22.0 0.03 14.1 22.0 1.7 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF3972 PF13118.6 KFM22403.1 - 0.032 14.7 3.9 0.11 12.9 3.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3972) DUF641 PF04859.12 KFM22403.1 - 0.21 11.9 20.1 0.35 11.2 3.4 3.1 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) DUF4472 PF14739.6 KFM22403.1 - 0.38 11.5 22.0 4.1 8.2 1.2 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4472) GAS PF13851.6 KFM22403.1 - 0.42 9.9 24.0 0.26 10.6 11.4 2.8 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 KFM22403.1 - 0.94 10.0 29.0 0.43 11.1 5.4 3.1 2 1 1 3 3 3 0 Apg6 coiled-coil region BRE1 PF08647.11 KFM22403.1 - 0.94 9.6 18.7 0.57 10.3 2.3 3.4 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase DUF4407 PF14362.6 KFM22403.1 - 1.3 8.3 23.4 4.1e+02 0.1 23.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2381 PF09544.10 KFM22403.1 - 2.2 7.8 19.3 5.2 6.5 1.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2381) TMF_DNA_bd PF12329.8 KFM22403.1 - 3.3 7.8 22.3 0.88 9.6 2.9 3.3 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Prefoldin_2 PF01920.20 KFM22403.1 - 3.3 7.7 16.4 7.7 6.5 0.5 3.2 3 0 0 3 3 3 0 Prefoldin subunit Tropomyosin_1 PF12718.7 KFM22403.1 - 5.1 7.2 22.7 9.5 6.4 14.2 3.0 2 1 0 2 2 2 0 Tropomyosin like Ribosomal_60s PF00428.19 KFM22404.1 - 3.5e-18 66.0 11.8 4.2e-18 65.7 11.8 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein ZirS_C PF16583.5 KFM22404.1 - 0.097 12.2 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Zinc-regulated secreted antivirulence protein C-terminal domain PRCC PF10253.9 KFM22405.1 - 8.1e-07 30.0 0.1 9.2e-07 29.9 0.1 1.2 1 0 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting Fer2 PF00111.27 KFM22406.1 - 4.6e-21 74.6 0.3 8.4e-21 73.7 0.3 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF2500 PF10694.9 KFM22406.1 - 0.0072 16.8 0.0 0.011 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2500) Fer2_4 PF13510.6 KFM22406.1 - 0.0084 16.1 0.2 0.019 15.0 0.0 1.7 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Acyltransferase PF01553.21 KFM22407.1 - 2.1e-12 46.8 0.0 3.3e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase GPAT_N PF14829.6 KFM22407.1 - 2.2e-11 43.6 0.0 4e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Glycerol-3-phosphate acyltransferase N-terminal UPF0047 PF01894.17 KFM22408.1 - 4.4e-18 65.5 0.0 5.2e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 zf_PR_Knuckle PF18445.1 KFM22408.1 - 0.17 11.8 0.1 0.35 10.7 0.1 1.5 1 0 0 1 1 1 0 PR zinc knuckle motif MRP-S25 PF13741.6 KFM22409.1 - 0.00074 19.1 1.7 0.24 11.0 0.4 3.1 1 1 2 3 3 3 2 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 KFM22409.1 - 0.0058 16.9 0.1 0.01 16.1 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S23 YGGT PF02325.17 KFM22410.1 - 9.9e-16 57.9 3.7 1.4e-15 57.4 3.7 1.3 1 0 0 1 1 1 1 YGGT family GDPD PF03009.17 KFM22411.1 - 1.3e-09 38.2 0.2 0.0011 18.8 0.0 2.1 1 1 1 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family Ank_4 PF13637.6 KFM22411.1 - 0.012 16.2 0.0 2.4 8.8 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Kinesin PF00225.23 KFM22412.1 - 8.9e-103 343.7 0.0 1.8e-102 342.7 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFM22412.1 - 2.7e-21 76.1 0.2 1.7e-20 73.5 0.0 2.4 2 0 0 2 2 2 1 Microtubule binding BRE1 PF08647.11 KFM22412.1 - 0.0047 17.0 16.0 0.0047 17.0 16.0 14.6 6 4 9 16 16 16 2 BRE1 E3 ubiquitin ligase CENP-F_leu_zip PF10473.9 KFM22412.1 - 0.0064 16.5 6.8 0.0064 16.5 6.8 15.8 4 1 13 17 17 17 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FtsJ PF01728.19 KFM22413.1 - 2.1e-14 54.0 0.0 3.1e-14 53.5 0.0 1.3 1 1 0 1 1 1 1 FtsJ-like methyltransferase S4 PF01479.25 KFM22413.1 - 6e-05 22.7 0.0 0.00014 21.5 0.0 1.6 1 0 0 1 1 1 1 S4 domain Methyltransf_11 PF08241.12 KFM22413.1 - 0.0013 19.3 0.5 0.66 10.7 0.2 2.4 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 KFM22413.1 - 0.014 16.0 0.4 0.28 11.9 0.2 2.4 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 KFM22413.1 - 0.1 12.5 0.1 1.4 8.7 0.1 2.2 1 1 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.16 KFM22416.1 - 2.7e-36 125.2 40.6 2.7e-36 125.2 40.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily PTR2 PF00854.21 KFM22416.1 - 0.0084 15.0 1.0 0.0084 15.0 1.0 2.2 3 0 0 3 3 3 1 POT family F-box-like PF12937.7 KFM22417.1 - 3.3e-06 26.9 0.2 1.1e-05 25.3 0.2 1.9 1 0 0 1 1 1 1 F-box-like MutS_V PF00488.21 KFM22418.1 - 8.4e-24 84.6 0.0 1.3e-23 84.0 0.0 1.3 1 0 0 1 1 1 1 MutS domain V ABC_tran PF00005.27 KFM22419.1 - 1.4e-42 145.5 0.0 5.7e-21 75.5 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KFM22419.1 - 1.2e-21 76.5 1.1 1.2e-21 76.5 1.1 2.6 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.6 KFM22419.1 - 6.3e-16 59.0 3.1 0.0053 16.6 0.1 4.2 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFM22419.1 - 7.7e-08 32.0 1.1 0.056 12.9 0.0 3.8 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KFM22419.1 - 1.6e-07 31.9 1.1 0.11 12.9 0.1 3.5 3 0 0 3 3 3 3 AAA ATPase domain AAA_29 PF13555.6 KFM22419.1 - 5.7e-06 26.0 0.4 0.12 12.2 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KFM22419.1 - 7.3e-06 26.6 4.6 0.065 13.7 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.6 KFM22419.1 - 8.3e-05 22.5 0.4 0.22 11.2 0.0 2.5 3 0 0 3 3 2 2 AAA ATPase domain NACHT PF05729.12 KFM22419.1 - 0.00013 21.9 0.0 0.17 11.8 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_30 PF13604.6 KFM22419.1 - 0.00046 20.0 5.5 0.25 11.1 0.0 3.4 4 1 0 4 4 2 2 AAA domain AAA PF00004.29 KFM22419.1 - 0.00049 20.5 0.1 0.52 10.8 0.0 3.6 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFM22419.1 - 0.00096 19.4 0.1 0.45 10.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 KFM22419.1 - 0.0014 18.6 0.3 1.8 8.5 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_28 PF13521.6 KFM22419.1 - 0.002 18.4 1.7 0.15 12.3 0.1 3.1 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 KFM22419.1 - 0.002 17.9 1.1 1.6 8.4 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_27 PF13514.6 KFM22419.1 - 0.002 17.7 0.1 0.5 9.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KFM22419.1 - 0.0036 17.4 0.2 1.1 9.4 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 KFM22419.1 - 0.0048 17.1 0.6 1.6 8.9 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_13 PF13166.6 KFM22419.1 - 0.015 14.0 0.1 0.4 9.3 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 KFM22419.1 - 0.017 14.7 0.2 6.3 6.3 0.0 3.1 3 0 0 3 3 3 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KFM22419.1 - 0.02 15.2 0.0 7.8 6.9 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.6 KFM22419.1 - 0.024 15.2 0.3 1 9.9 0.0 3.1 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.14 KFM22419.1 - 0.026 14.5 0.8 14 5.7 0.1 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 KFM22419.1 - 0.031 14.2 0.5 2.9 7.8 0.1 2.6 2 0 0 2 2 2 0 NTPase IstB_IS21 PF01695.17 KFM22419.1 - 0.054 13.2 0.4 3.1 7.5 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein SRP54 PF00448.22 KFM22419.1 - 0.075 12.7 1.3 4.8 6.8 0.1 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NB-ARC PF00931.22 KFM22419.1 - 0.37 9.9 1.3 46 3.1 0.0 3.1 3 0 0 3 3 3 0 NB-ARC domain AAA_25 PF13481.6 KFM22419.1 - 4.7 6.7 7.3 3.6 7.1 0.2 3.5 4 2 0 4 4 4 0 AAA domain Mitofilin PF09731.9 KFM22420.1 - 1.1e-24 87.3 9.4 1.1e-24 87.3 9.4 1.3 1 1 0 1 1 1 1 Mitochondrial inner membrane protein MttA_Hcf106 PF02416.16 KFM22420.1 - 0.1 12.0 0.2 0.2 11.0 0.2 1.4 1 0 0 1 1 1 0 mttA/Hcf106 family Acetyltransf_1 PF00583.25 KFM22421.1 - 9.6e-14 51.6 0.1 1.1e-13 51.4 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFM22421.1 - 2.9e-09 36.9 0.1 3.4e-09 36.7 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFM22421.1 - 3.8e-06 27.2 0.1 6e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KFM22421.1 - 3.9e-06 27.1 0.1 4.7e-06 26.8 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KFM22421.1 - 2.5e-05 25.0 0.4 3.2e-05 24.6 0.4 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KFM22421.1 - 0.00017 21.6 0.1 0.00031 20.8 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFM22421.1 - 0.013 15.5 0.1 0.021 14.8 0.1 1.4 1 0 0 1 1 1 0 FR47-like protein Enolase_C PF00113.22 KFM22422.1 - 7.2e-140 465.3 0.1 1e-139 464.8 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KFM22422.1 - 3.2e-59 198.8 0.3 6.5e-59 197.8 0.3 1.6 1 0 0 1 1 1 1 Enolase, N-terminal domain UPF0060 PF02694.15 KFM22422.1 - 1.9e-32 111.7 6.9 3.6e-32 110.8 6.9 1.4 1 0 0 1 1 1 1 Uncharacterised BCR, YnfA/UPF0060 family MR_MLE_C PF13378.6 KFM22422.1 - 1.1e-10 41.5 0.0 2.1e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KFM22422.1 - 1e-06 28.1 0.9 1.8e-06 27.3 0.1 1.8 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus DUF5582 PF17819.1 KFM22422.1 - 0.017 15.6 0.1 0.38 11.2 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5582) RIIa PF02197.17 KFM22422.1 - 0.036 13.7 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit MCM_bind PF09739.9 KFM22424.1 - 1.4e-78 264.8 0.0 3.3e-25 88.6 0.0 4.0 2 1 2 4 4 4 4 Mini-chromosome maintenance replisome factor DBC1 PF14443.6 KFM22425.1 - 2.4e-23 82.4 0.0 3.8e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 DBC1 EF-hand_6 PF13405.6 KFM22425.1 - 0.14 12.1 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain Chalcone_2 PF16035.5 KFM22426.1 - 2.1e-07 31.0 0.0 0.00029 20.7 0.1 2.2 1 1 1 2 2 2 2 Chalcone isomerase like Chalcone_3 PF16036.5 KFM22426.1 - 1.5e-05 25.2 0.0 0.00022 21.4 0.0 2.3 1 1 0 1 1 1 1 Chalcone isomerase-like Chalcone PF02431.15 KFM22426.1 - 1.7e-05 24.3 0.2 0.0027 17.1 0.0 2.2 1 1 1 2 2 2 2 Chalcone-flavanone isomerase IPK PF03770.16 KFM22427.1 - 0.014 15.2 0.1 4.6 7.0 0.0 2.1 2 0 0 2 2 2 0 Inositol polyphosphate kinase KH_6 PF15985.5 KFM22428.1 - 1.7e-12 47.5 0.0 5.2e-12 45.9 0.0 1.9 2 0 0 2 2 2 1 KH domain LTXXQ PF07813.12 KFM22429.1 - 0.0027 18.4 20.6 0.0039 17.9 0.3 4.9 4 1 0 4 4 4 1 LTXXQ motif family protein bZIP_1 PF00170.21 KFM22429.1 - 0.4 10.8 21.0 1.1 9.4 8.4 2.5 2 0 0 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.15 KFM22429.1 - 3.9 7.6 25.6 1.5 8.9 9.6 2.5 2 0 0 2 2 2 0 Basic region leucine zipper TPT PF03151.16 KFM22430.1 - 7.3e-05 22.2 5.4 0.004 16.5 2.1 2.0 2 0 0 2 2 2 2 Triose-phosphate Transporter family CesT PF05932.13 KFM22434.1 - 0.13 12.4 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Tir chaperone protein (CesT) family CLP_protease PF00574.23 KFM22435.1 - 3.5e-38 131.3 0.0 5.3e-38 130.7 0.0 1.2 1 0 0 1 1 1 1 Clp protease PRORP PF16953.5 KFM22436.1 - 9.7e-39 133.3 0.0 1.5e-38 132.7 0.0 1.2 1 0 0 1 1 1 1 Protein-only RNase P PPR_long PF17177.4 KFM22436.1 - 4.5e-28 98.1 0.1 2.1e-27 95.9 0.0 2.0 2 1 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP RNase_Zc3h12a PF11977.8 KFM22436.1 - 0.002 17.9 0.0 0.0037 17.0 0.0 1.3 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain PPR_3 PF13812.6 KFM22436.1 - 0.014 15.4 0.0 21 5.3 0.0 3.1 2 1 1 3 3 3 0 Pentatricopeptide repeat domain PPR_2 PF13041.6 KFM22436.1 - 0.054 13.7 0.0 34 4.7 0.0 3.4 2 1 2 4 4 4 0 PPR repeat family PPR PF01535.20 KFM22436.1 - 0.065 13.5 0.1 61 4.2 0.0 3.9 4 0 0 4 4 4 0 PPR repeat Ribosom_S12_S23 PF00164.25 KFM22437.1 - 2.2e-50 169.1 0.2 2.9e-50 168.7 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Cytochrom_C PF00034.21 KFM22438.1 - 0.15 13.2 1.3 4.4 8.5 0.3 2.3 2 0 0 2 2 2 0 Cytochrome c PRIMA1 PF16101.5 KFM22438.1 - 0.46 10.5 3.4 0.18 11.9 0.4 1.8 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Lactamase_B_5 PF14597.6 KFM22440.1 - 1.1e-08 34.8 0.0 1.6e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B PF00753.27 KFM22440.1 - 5.2e-06 26.6 0.1 9.2e-06 25.8 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Spt20 PF12090.8 KFM22443.1 - 0.92 9.1 6.2 0.95 9.0 6.2 1.1 1 0 0 1 1 1 0 Spt20 family PI3_PI4_kinase PF00454.27 KFM22444.1 - 6.2e-16 59.0 0.0 1e-15 58.2 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 KFM22444.1 - 5.1e-07 29.4 0.1 1.4e-06 28.0 0.1 1.7 1 0 0 1 1 1 1 FATC domain FAT PF02259.23 KFM22444.1 - 0.024 13.9 0.0 0.048 12.9 0.0 1.5 1 0 0 1 1 1 0 FAT domain PABP PF00658.18 KFM22446.1 - 5.3e-16 58.5 0.6 6.4e-16 58.3 0.6 1.1 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain HTH_9 PF08221.11 KFM22446.1 - 0.048 13.8 0.0 0.061 13.4 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain DnaJ PF00226.31 KFM22447.1 - 7.5e-19 67.6 1.4 1.2e-17 63.7 0.7 2.5 2 0 0 2 2 2 1 DnaJ domain Sec63 PF02889.16 KFM22447.1 - 8.2e-14 51.4 0.0 1.6e-13 50.5 0.0 1.4 1 1 0 1 1 1 1 Sec63 Brl domain Prefoldin_2 PF01920.20 KFM22448.1 - 1e-14 54.4 10.3 1e-14 54.4 10.3 2.0 1 1 1 2 2 2 1 Prefoldin subunit Rx_N PF18052.1 KFM22448.1 - 0.0042 17.3 1.6 0.0042 17.3 1.6 2.0 2 0 0 2 2 2 1 Rx N-terminal domain ADIP PF11559.8 KFM22448.1 - 0.054 13.6 15.3 0.51 10.4 4.1 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding PRKG1_interact PF15898.5 KFM22448.1 - 5.1 8.0 15.4 4.2 8.3 7.0 2.1 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Peptidase_S46 PF10459.9 KFM22448.1 - 9.8 4.7 12.1 10 4.6 12.1 1.0 1 0 0 1 1 1 0 Peptidase S46 Peptidase_S39 PF02122.15 KFM22449.1 - 0.035 13.6 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 Peptidase S39 Ribosomal_60s PF00428.19 KFM22449.1 - 4.7 7.9 8.3 0.88 10.2 4.6 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein SKI PF01202.22 KFM22450.1 - 1.9e-16 60.6 0.2 2.8e-15 56.8 0.2 2.0 1 1 1 2 2 2 1 Shikimate kinase Flavin_Reduct PF01613.18 KFM22452.1 - 1.2e-19 70.9 0.3 1.7e-19 70.4 0.3 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Mic1 PF07035.12 KFM22453.1 - 0.0016 18.2 0.0 0.0026 17.5 0.0 1.2 1 0 0 1 1 1 1 Colon cancer-associated protein Mic1-like EnY2 PF10163.9 KFM22454.1 - 1.3e-12 47.8 0.0 1.6e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Transcription factor e(y)2 Nucleotid_trans PF03407.16 KFM22455.1 - 8.4e-42 143.5 0.5 1.2e-41 143.0 0.5 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase QueF_N PF14819.6 KFM22455.1 - 0.1 12.9 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term SAPIS-gp6 PF16722.5 KFM22455.1 - 0.15 12.4 0.9 2.6 8.5 0.1 2.4 2 0 0 2 2 2 0 Pathogenicity island protein gp6 in Staphylococcus Ribosomal_S16 PF00886.19 KFM22456.1 - 4.5e-07 29.8 0.0 5.7e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 Bromo_TP PF07524.13 KFM22459.1 - 3.2e-13 49.5 0.1 4.8e-13 48.9 0.1 1.3 1 0 0 1 1 1 1 Bromodomain associated TAF8_C PF10406.9 KFM22459.1 - 1.2e-10 41.8 0.1 1.2e-10 41.8 0.1 2.1 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term MlaD PF02470.20 KFM22460.1 - 1.9e-12 47.3 0.0 3.8e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 MlaD protein Phasin_2 PF09361.10 KFM22460.1 - 0.39 11.0 5.1 5.6 7.3 0.1 2.7 2 1 0 2 2 2 0 Phasin protein WD40 PF00400.32 KFM22461.1 - 3.4e-12 46.7 1.8 1.2e-05 26.0 0.3 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat DDR PF08841.10 KFM22461.1 - 0.98 8.3 3.6 1.6 7.6 3.6 1.3 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain BSD PF03909.17 KFM22462.1 - 1.3e-06 28.3 0.0 2.3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 BSD domain NAD_binding_9 PF13454.6 KFM22462.1 - 0.0084 16.1 0.0 0.02 14.9 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding RabGAP-TBC PF00566.18 KFM22463.1 - 1.6e-49 168.5 0.0 2.5e-49 167.8 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain tRNA-synt_1b PF00579.25 KFM22464.1 - 1.6e-55 188.5 0.0 1.8e-55 188.3 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) IMPDH PF00478.25 KFM22465.1 - 1.2e-07 31.0 0.0 1.3e-07 30.9 0.0 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Cyt-b5 PF00173.28 KFM22466.1 - 7.8e-22 77.2 0.0 1e-21 76.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IRK_C PF17655.1 KFM22467.1 - 2.8e-20 72.6 0.0 4.6e-18 65.4 0.0 2.1 1 1 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KFM22467.1 - 1.8e-16 60.2 9.6 2.6e-14 53.2 9.6 2.1 1 1 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 KFM22467.1 - 2e-08 34.1 2.3 3.6e-08 33.2 2.3 1.5 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 KFM22467.1 - 0.053 12.8 5.1 0.075 12.2 5.1 1.2 1 0 0 1 1 1 0 Ion transport protein PhyH PF05721.13 KFM22469.1 - 1.6e-58 198.5 0.0 1.9e-58 198.2 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) RRM_1 PF00076.22 KFM22470.1 - 6.9e-14 51.4 0.0 1.3e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lsm_interact PF05391.11 KFM22470.1 - 0.0032 16.9 0.1 0.011 15.2 0.1 1.9 1 0 0 1 1 1 1 Lsm interaction motif DUF844 PF05815.11 KFM22470.1 - 0.02 14.1 0.1 0.04 13.1 0.1 1.4 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) Suf PF05843.14 KFM22470.1 - 1.3 9.0 5.2 26 4.7 0.0 3.5 3 1 0 3 3 3 0 Suppressor of forked protein (Suf) CDC27 PF09507.10 KFM22470.1 - 5.9 6.2 10.7 12 5.2 10.7 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Nucleoside_tran PF01733.18 KFM22471.1 - 3.7e-33 115.2 0.1 4.8e-32 111.6 0.1 2.0 1 1 0 1 1 1 1 Nucleoside transporter MFS_1 PF07690.16 KFM22471.1 - 7.1e-05 21.9 25.1 0.00068 18.7 24.9 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Mtc PF03820.17 KFM22471.1 - 0.11 11.5 0.0 0.27 10.2 0.0 1.6 1 0 0 1 1 1 0 Tricarboxylate carrier Nucleoside_tran PF01733.18 KFM22472.1 - 9.9e-36 123.7 0.1 9.9e-36 123.7 0.1 1.6 2 0 0 2 2 2 1 Nucleoside transporter LisH PF08513.11 KFM22473.1 - 0.081 12.9 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 LisH Cupin_8 PF13621.6 KFM22476.1 - 1.8e-09 37.7 0.0 1.9e-09 37.6 0.0 1.0 1 0 0 1 1 1 1 Cupin-like domain RHS_repeat PF05593.14 KFM22476.1 - 0.068 13.7 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 RHS Repeat VPS11_C PF12451.8 KFM22477.1 - 6.7e-11 42.2 0.0 1.2e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 KFM22477.1 - 0.24 11.5 0.4 2.2 8.4 0.0 2.1 2 0 0 2 2 2 0 Zinc-finger Med31 PF05669.12 KFM22478.1 - 0.0007 19.6 0.0 0.00089 19.2 0.0 1.2 1 0 0 1 1 1 1 SOH1 Mpv17_PMP22 PF04117.12 KFM22479.1 - 3.4e-25 88.0 5.6 1.3e-15 57.3 2.3 2.3 2 0 0 2 2 2 2 Mpv17 / PMP22 family RAMA PF18755.1 KFM22479.1 - 0.72 10.3 4.6 42 4.6 0.2 3.1 3 0 0 3 3 3 0 Restriction Enzyme Adenine Methylase Associated DUF2530 PF10745.9 KFM22479.1 - 3.2 8.1 6.7 0.76 10.1 0.1 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2530) Kinesin PF00225.23 KFM22480.1 - 1.2e-102 343.2 0.3 1.6e-102 342.8 0.3 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFM22480.1 - 8.2e-19 68.0 0.3 2.1e-18 66.7 0.0 1.8 2 0 0 2 2 2 1 Microtubule binding PhoH PF02562.16 KFM22480.1 - 0.0055 16.2 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein DUF3323 PF11796.8 KFM22480.1 - 0.083 12.8 2.5 0.16 11.8 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) Ribosomal_L31 PF01197.18 KFM22481.1 - 2.4e-18 66.1 0.1 3.5e-18 65.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L31 G-patch PF01585.23 KFM22482.1 - 8.6e-11 41.6 3.0 1.8e-10 40.5 3.0 1.6 1 0 0 1 1 1 1 G-patch domain zf-C2H2_jaz PF12171.8 KFM22482.1 - 4.2e-06 26.9 3.6 6.4e-06 26.3 3.6 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM22482.1 - 0.00025 21.3 0.6 0.00044 20.5 0.6 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf_UBZ PF18439.1 KFM22482.1 - 0.0063 16.1 0.2 0.012 15.1 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger zf-DBF PF07535.12 KFM22482.1 - 0.0065 16.5 1.7 0.013 15.6 1.7 1.5 1 0 0 1 1 1 1 DBF zinc finger zf-C2H2_2 PF12756.7 KFM22482.1 - 0.013 15.9 1.2 0.021 15.1 1.2 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Suf PF05843.14 KFM22485.1 - 1.1 9.2 5.9 1.3 8.9 5.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Herpes_DNAp_acc PF04929.12 KFM22485.1 - 2.9 6.8 9.0 3.5 6.5 9.0 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor RNA_pol_Rpb2_6 PF00562.28 KFM22489.1 - 5.9e-124 414.1 0.0 4.1e-123 411.3 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_3 PF04565.16 KFM22489.1 - 5.6e-23 80.9 0.0 1.2e-22 79.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 KFM22489.1 - 2.5e-18 66.2 0.0 6e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 KFM22489.1 - 3e-14 53.1 3.3 2.5e-13 50.1 3.3 2.3 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_1 PF04563.15 KFM22489.1 - 0.0091 15.5 0.0 0.023 14.2 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb1_1 PF04997.12 KFM22490.1 - 3.4e-41 141.6 1.5 5.5e-41 140.9 1.5 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 KFM22490.1 - 2e-38 132.2 0.0 1.5e-25 90.4 0.0 2.5 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KFM22490.1 - 8.8e-07 29.0 0.0 2.6e-06 27.4 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 Coatomer_b_Cpla PF14806.6 KFM22491.1 - 5.8e-40 136.2 0.0 6.6e-40 136.1 0.0 1.0 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Cytochrom_B559 PF00283.19 KFM22495.1 - 2.8e-30 103.4 7.5 2.7e-16 58.7 1.8 2.3 2 0 0 2 2 2 2 Cytochrome b559, alpha (gene psbE) and beta (gene psbF)subunits Cytochrom_B559a PF00284.20 KFM22495.1 - 3e-20 71.7 0.3 6.2e-20 70.7 0.2 1.6 2 0 0 2 2 2 1 Lumenal portion of Cytochrome b559, alpha (gene psbE) subunit Oxidored_nitro PF00148.19 KFM22496.1 - 1e-72 245.1 0.0 1.2e-72 244.9 0.0 1.0 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase PCP_red PF08369.10 KFM22496.1 - 9.5e-20 70.5 0.3 3.2e-19 68.9 0.1 2.1 2 0 0 2 2 2 1 Proto-chlorophyllide reductase 57 kD subunit HRDC PF00570.23 KFM22496.1 - 0.16 12.0 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 HRDC domain Fer4 PF00037.27 KFM22497.1 - 9.3e-15 53.7 11.7 2.5e-07 30.2 2.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 KFM22497.1 - 2.1e-10 40.2 13.2 6.8e-06 25.9 2.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KFM22497.1 - 8.6e-10 39.1 14.6 2.1e-09 37.8 14.9 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 KFM22497.1 - 2.4e-09 37.2 13.6 3.9e-09 36.5 13.6 1.4 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_4 PF12800.7 KFM22497.1 - 3.7e-09 36.4 17.6 8.3e-05 22.8 2.7 2.5 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_10 PF13237.6 KFM22497.1 - 4.8e-09 36.2 13.9 9.5e-05 22.4 4.4 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 KFM22497.1 - 1.4e-08 35.1 9.8 0.00047 20.7 2.1 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 KFM22497.1 - 1.4e-08 35.5 10.2 0.0008 20.3 3.3 2.1 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 KFM22497.1 - 2.6e-08 33.9 14.7 5.5e-08 32.9 14.8 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 KFM22497.1 - 1.5e-07 31.1 17.3 0.00064 19.7 3.7 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_22 PF17179.4 KFM22497.1 - 7.1e-06 26.8 9.9 0.0014 19.4 1.2 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 KFM22497.1 - 6.9e-05 23.5 20.2 0.0028 18.5 5.1 2.5 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_13 PF13370.6 KFM22497.1 - 0.00038 20.9 15.0 0.0022 18.5 3.7 2.2 1 1 1 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_8 PF13183.6 KFM22497.1 - 0.0005 20.5 16.3 0.025 15.0 3.4 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_18 PF13746.6 KFM22497.1 - 0.0053 16.9 13.4 0.24 11.6 3.4 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.6 KFM22497.1 - 0.008 16.9 10.3 0.012 16.3 1.7 2.2 2 0 0 2 2 2 1 4Fe-4S single cluster domain ETF_QO PF05187.13 KFM22497.1 - 0.066 13.4 4.9 0.099 12.8 4.8 1.3 1 1 0 1 1 1 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S BPD_transp_1 PF00528.22 KFM22498.1 - 1.8e-19 70.2 15.0 1.8e-19 70.2 15.0 2.2 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component TcpE PF12648.7 KFM22498.1 - 0.0081 16.7 1.6 0.0081 16.7 1.6 3.0 3 1 0 3 3 3 1 TcpE family PSII PF00421.19 KFM22499.1 - 3e-101 339.6 11.9 3.3e-101 339.5 11.9 1.0 1 0 0 1 1 1 1 Photosystem II protein PSII PF00421.19 KFM22500.1 - 1.4e-137 459.4 0.4 1.6e-137 459.3 0.4 1.0 1 0 0 1 1 1 1 Photosystem II protein PsbH PF00737.20 KFM22501.1 - 5.1e-30 103.0 2.7 7.2e-30 102.5 2.7 1.2 1 0 0 1 1 1 1 Photosystem II 10 kDa phosphoprotein Ribosomal_L20 PF00453.18 KFM22502.1 - 4.7e-34 116.7 3.4 5.2e-34 116.5 3.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L20 Toxin_R_bind_C PF07951.12 KFM22502.1 - 0.04 13.6 0.3 0.042 13.5 0.3 1.1 1 0 0 1 1 1 0 Clostridium neurotoxin, C-terminal receptor binding CemA PF03040.14 KFM22503.1 - 1.1e-73 248.0 8.3 1.3e-73 247.8 8.3 1.0 1 0 0 1 1 1 1 CemA family Ribosomal_L14 PF00238.19 KFM22504.1 - 8.2e-52 174.4 2.0 9.1e-52 174.3 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Ribosomal_S8 PF00410.19 KFM22505.1 - 1.2e-45 154.5 0.2 1.4e-45 154.3 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S8 YjcQ PF09639.10 KFM22505.1 - 0.044 14.0 0.1 0.078 13.2 0.1 1.4 1 0 0 1 1 1 0 YjcQ protein DUF3240 PF11582.8 KFM22505.1 - 0.047 13.8 0.0 0.078 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3240) eIF-1a PF01176.19 KFM22506.1 - 8.7e-26 89.5 0.1 9.4e-26 89.4 0.1 1.0 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 RsgA_N PF16745.5 KFM22506.1 - 6.4e-05 22.6 0.1 0.00011 21.8 0.1 1.5 1 1 0 1 1 1 1 RsgA N-terminal domain S1 PF00575.23 KFM22506.1 - 0.021 15.1 0.0 0.028 14.7 0.0 1.2 1 0 0 1 1 1 0 S1 RNA binding domain Ribosomal_S9 PF00380.19 KFM22507.1 - 1.5e-34 119.1 0.3 1.7e-34 118.9 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 TPR_1 PF00515.28 KFM22508.1 - 1.2e-18 66.1 10.0 1.5e-08 34.1 0.4 4.2 3 1 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFM22508.1 - 7.8e-11 41.2 10.5 0.00019 21.3 0.3 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFM22508.1 - 1.6e-09 37.9 14.0 3.8e-07 30.3 7.2 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFM22508.1 - 1e-08 34.7 8.0 2.6e-05 24.1 0.1 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFM22508.1 - 5.6e-07 30.1 5.9 5e-06 27.1 4.1 2.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFM22508.1 - 3.2e-06 27.5 3.8 0.015 16.1 0.1 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFM22508.1 - 6.9e-06 25.7 6.6 0.0016 18.4 0.1 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFM22508.1 - 8.2e-06 26.1 4.1 0.015 15.9 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFM22508.1 - 9.4e-06 25.2 14.2 0.011 15.4 0.8 3.7 2 1 1 3 3 3 2 TPR repeat TPR_17 PF13431.6 KFM22508.1 - 5.3e-05 23.3 2.2 0.18 12.3 0.1 3.8 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFM22508.1 - 0.00072 19.3 13.4 0.0095 15.8 0.6 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 KFM22508.1 - 0.0011 18.3 0.4 0.0047 16.2 0.2 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFM22508.1 - 0.0017 18.9 2.6 0.22 12.0 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.18 KFM22508.1 - 0.0028 17.7 7.1 0.052 13.6 1.8 3.1 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain HemY_N PF07219.13 KFM22508.1 - 0.0033 17.6 0.4 0.39 10.9 0.2 2.3 1 1 1 2 2 2 1 HemY protein N-terminus TPR_MalT PF17874.1 KFM22508.1 - 0.019 14.3 0.2 0.044 13.1 0.2 1.6 1 1 0 1 1 1 0 MalT-like TPR region DUF2225 PF09986.9 KFM22508.1 - 0.094 12.4 1.9 0.28 10.9 0.9 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) Cohesin_load PF10345.9 KFM22508.1 - 0.1 11.0 1.0 1.7 7.0 1.0 2.0 1 1 0 1 1 1 0 Cohesin loading factor Fis1_TPR_C PF14853.6 KFM22508.1 - 0.58 10.3 6.1 0.45 10.6 0.5 3.0 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat BRCT PF00533.26 KFM22509.1 - 0.004 17.5 0.0 0.03 14.7 0.0 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain EF-hand_1 PF00036.32 KFM22510.1 - 1.6e-40 133.7 10.8 2.5e-09 36.0 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KFM22510.1 - 1.6e-33 114.9 3.4 1.6e-17 63.7 1.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KFM22510.1 - 1e-29 102.1 10.2 4.6e-15 55.2 0.6 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 KFM22510.1 - 3e-29 98.4 6.9 3.1e-09 36.0 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KFM22510.1 - 7.5e-25 85.3 8.6 4.6e-06 25.9 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KFM22510.1 - 1.5e-12 47.7 0.1 1.5e-06 28.4 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 KFM22510.1 - 5.3e-08 33.2 0.2 0.0076 16.6 0.1 2.3 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFM22510.1 - 1e-07 31.8 1.1 0.0016 18.4 0.1 2.9 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 KFM22510.1 - 1.1e-05 26.2 0.3 0.0095 16.8 0.0 2.6 2 1 1 3 3 3 1 EF-hand domain TerB PF05099.13 KFM22510.1 - 0.00017 21.5 0.2 0.26 11.2 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB UPF0154 PF03672.13 KFM22510.1 - 0.00038 20.4 0.0 0.17 11.9 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 KFM22510.1 - 0.0022 18.0 0.1 0.0059 16.7 0.1 1.8 1 0 0 1 1 1 1 Ca2+ insensitive EF hand Caleosin PF05042.13 KFM22510.1 - 0.0024 17.8 0.4 0.72 9.8 0.0 3.3 1 1 3 4 4 4 1 Caleosin related protein Dockerin_1 PF00404.18 KFM22510.1 - 0.016 15.4 3.3 0.63 10.3 0.4 2.9 1 1 1 2 2 2 0 Dockerin type I domain SurA_N_2 PF13623.6 KFM22510.1 - 0.021 14.7 0.5 0.98 9.3 0.1 2.2 1 1 1 2 2 2 0 SurA N-terminal domain DUF5580 PF17743.1 KFM22510.1 - 0.021 13.4 0.0 0.027 13.0 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5580) SurA_N_3 PF13624.6 KFM22510.1 - 0.098 12.4 0.3 4.1 7.2 0.2 2.0 1 1 1 2 2 2 0 SurA N-terminal domain p25-alpha PF05517.12 KFM22510.1 - 0.1 12.8 0.5 14 5.8 0.0 2.3 1 1 1 2 2 2 0 p25-alpha DUF3349 PF11829.8 KFM22510.1 - 0.11 13.3 0.2 5.8 7.8 0.0 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) EF-hand_14 PF17959.1 KFM22510.1 - 0.12 12.7 0.4 13 6.2 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain Poly_export PF02563.16 KFM22510.1 - 0.14 12.4 0.0 2.7 8.3 0.0 2.6 2 1 1 3 3 3 0 Polysaccharide biosynthesis/export protein Pentapeptide_2 PF01469.18 KFM22514.1 - 4.9e-14 51.9 51.6 7.2e-08 32.2 17.9 2.9 2 1 0 2 2 2 2 Pentapeptide repeats (8 copies) OrfB_Zn_ribbon PF07282.11 KFM22515.1 - 6.2e-05 22.9 6.8 0.00026 20.8 6.8 1.9 1 1 0 1 1 1 1 Putative transposase DNA-binding domain OTT_1508_deam PF14441.6 KFM22515.1 - 0.016 15.2 0.9 0.031 14.3 0.9 1.5 1 0 0 1 1 1 0 OTT_1508-like deaminase tRNA-synt_2 PF00152.20 KFM22516.1 - 4.4e-70 236.3 0.0 5.8e-37 127.4 0.0 2.2 1 1 1 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 KFM22516.1 - 0.00073 19.1 0.1 0.34 10.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.25 KFM22516.1 - 0.0014 18.5 0.2 0.0035 17.3 0.2 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain SIMPL PF04402.14 KFM22516.1 - 0.58 10.6 7.8 0.15 12.5 4.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF541) NARP1 PF12569.8 KFM22516.1 - 0.78 8.6 4.0 1.1 8.1 4.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CENP-T_C PF15511.6 KFM22517.1 - 1.9e-08 34.4 0.1 2.4e-08 34.0 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KFM22517.1 - 0.00014 22.2 0.1 0.00018 21.8 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KFM22517.1 - 0.00021 21.4 0.1 0.00029 20.9 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.13 KFM22517.1 - 0.001 19.0 0.0 0.0016 18.4 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated CBFD_NFYB_HMF PF00808.23 KFM22517.1 - 0.0012 19.1 0.0 0.002 18.4 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFM22517.1 - 0.0014 19.0 0.2 0.0016 18.8 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KFM22517.1 - 0.035 14.2 0.0 0.04 14.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit SAP PF02037.27 KFM22518.1 - 1.1e-06 28.2 4.5 1.8e-06 27.5 4.5 1.3 1 0 0 1 1 1 1 SAP domain TGT PF01702.18 KFM22519.1 - 3.2e-101 339.0 0.0 1.1e-99 333.9 0.0 2.0 1 1 0 1 1 1 1 Queuine tRNA-ribosyltransferase PPIP5K2_N PF18086.1 KFM22520.1 - 7.7e-38 128.5 0.0 1.1e-37 128.0 0.0 1.2 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain LTP_2 PF14368.6 KFM22521.1 - 0.015 15.3 2.4 0.02 15.0 2.5 1.4 1 1 0 1 1 1 0 Probable lipid transfer RCDG1 PF15725.5 KFM22522.1 - 0.0032 17.9 2.7 0.005 17.2 2.7 1.4 1 0 0 1 1 1 1 Renal cancer differentiation gene 1 protein Histone_H2A_C PF16211.5 KFM22523.1 - 1.1e-19 69.9 1.3 1.9e-19 69.1 1.3 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KFM22523.1 - 4.7e-15 56.1 0.0 5.8e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFM22523.1 - 1.6e-05 25.1 0.0 2.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 KFM22524.1 - 2e-08 34.3 0.1 2.5e-08 34.0 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KFM22524.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KFM22524.1 - 0.00022 21.3 0.1 0.00031 20.8 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.13 KFM22524.1 - 0.0011 18.9 0.1 0.0017 18.4 0.1 1.2 1 0 0 1 1 1 1 Bromodomain associated CBFD_NFYB_HMF PF00808.23 KFM22524.1 - 0.0013 19.0 0.0 0.0022 18.3 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFM22524.1 - 0.0015 18.9 0.1 0.0017 18.8 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KFM22524.1 - 0.033 14.3 0.0 0.037 14.1 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 KFM22525.1 - 7.6e-53 178.4 2.5 8.5e-53 178.2 2.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 KFM22525.1 - 0.0001 22.9 1.4 0.00013 22.6 1.4 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 KFM22525.1 - 0.00018 21.8 0.0 0.00027 21.2 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KFM22525.1 - 0.00026 21.0 0.7 0.00035 20.6 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KFM22525.1 - 0.0015 18.8 0.1 0.0029 17.9 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KFM22525.1 - 0.0096 16.0 0.2 0.018 15.1 0.0 1.5 2 0 0 2 2 2 1 Transcription initiation factor IID, 31kD subunit PRAI PF00697.22 KFM22525.1 - 0.17 11.6 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase MCM PF00493.23 KFM22526.1 - 3e-99 330.7 0.0 4.6e-99 330.1 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KFM22526.1 - 2.4e-37 127.6 0.0 5e-37 126.6 0.0 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KFM22526.1 - 4.7e-25 87.8 0.8 1.8e-24 86.0 0.8 2.1 1 0 0 1 1 1 1 MCM AAA-lid domain MCM2_N PF12619.8 KFM22526.1 - 4.6e-15 56.2 16.3 4.6e-15 56.2 16.3 2.8 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.6 KFM22526.1 - 2.3e-12 47.4 0.0 5.8e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KFM22526.1 - 1.5e-08 34.3 0.1 5.8e-07 29.1 0.1 2.4 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KFM22526.1 - 2.7e-07 30.6 0.0 6.9e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KFM22526.1 - 0.0018 18.0 0.1 0.0038 16.9 0.1 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 KFM22526.1 - 0.0034 17.2 0.0 0.0072 16.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) zf-Sec23_Sec24 PF04810.15 KFM22526.1 - 0.0038 17.3 0.0 0.0068 16.4 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger AAA_lid_2 PF17863.1 KFM22526.1 - 0.0044 16.8 0.2 0.0044 16.8 0.2 2.5 2 0 0 2 2 2 1 AAA lid domain AAA_30 PF13604.6 KFM22526.1 - 0.025 14.3 0.7 0.025 14.3 0.7 1.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KFM22526.1 - 0.093 13.2 0.0 0.43 11.0 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Nudix_N_2 PF14803.6 KFM22526.1 - 0.27 11.2 2.1 0.65 10.0 2.1 1.6 1 0 0 1 1 1 0 Nudix N-terminal RVT_1 PF00078.27 KFM22527.1 - 0.23 10.9 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) MMR_HSR1 PF01926.23 KFM22528.1 - 4.3e-39 133.1 0.0 3.3e-25 88.4 0.0 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase KH_dom-like PF14714.6 KFM22528.1 - 1.3e-27 95.9 0.2 2.2e-27 95.2 0.2 1.4 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal GTP_EFTU PF00009.27 KFM22528.1 - 5.6e-15 55.4 0.5 7.5e-10 38.7 0.3 4.4 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KFM22528.1 - 4.4e-13 49.0 0.0 7.4e-11 41.8 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KFM22528.1 - 1.1e-07 32.1 0.0 0.0024 18.0 0.1 2.5 1 1 1 2 2 2 2 Dynamin family Complex1_LYR PF05347.15 KFM22528.1 - 0.00043 20.3 2.6 0.0006 19.8 0.3 2.3 2 0 0 2 2 2 1 Complex 1 protein (LYR family) AIG1 PF04548.16 KFM22528.1 - 0.0021 17.4 0.0 0.0047 16.3 0.0 1.6 1 0 0 1 1 1 1 AIG1 family Roc PF08477.13 KFM22528.1 - 0.0039 17.4 0.0 0.3 11.3 0.0 2.9 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KFM22528.1 - 0.0047 16.8 0.0 0.15 12.0 0.0 2.9 3 0 0 3 3 3 1 RsgA GTPase NOG1 PF06858.14 KFM22528.1 - 0.0079 16.0 0.6 0.3 10.9 0.4 3.2 2 1 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) cobW PF02492.19 KFM22528.1 - 0.022 14.4 0.1 0.098 12.2 0.0 2.1 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Nuc_deoxyrib_tr PF05014.15 KFM22528.1 - 0.066 13.2 1.8 4.5 7.3 0.3 2.8 2 1 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase DUF2868 PF11067.8 KFM22528.1 - 0.072 12.6 3.0 0.15 11.6 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2868) AAA_22 PF13401.6 KFM22528.1 - 0.084 13.1 0.1 0.54 10.5 0.0 2.3 3 0 0 3 3 2 0 AAA domain ABC_tran PF00005.27 KFM22528.1 - 0.19 12.2 0.0 0.4 11.2 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_15 PF13175.6 KFM22528.1 - 0.36 10.5 0.1 0.71 9.5 0.0 1.4 2 0 0 2 2 2 0 AAA ATPase domain Sugar_tr PF00083.24 KFM22529.1 - 3.1e-29 102.2 0.0 3.4e-29 102.0 0.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter RskA PF10099.9 KFM22529.1 - 0.11 12.8 0.1 0.12 12.6 0.1 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA YbgT_YccB PF08173.11 KFM22529.1 - 7.5 6.8 7.3 8 6.7 0.1 2.3 2 0 0 2 2 2 0 Membrane bound YbgT-like protein IF-2B PF01008.17 KFM22530.1 - 3.4e-62 210.2 0.0 3.9e-62 210.0 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DAGAT PF03982.13 KFM22531.1 - 7.4e-47 159.7 0.0 8.5e-47 159.5 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.21 KFM22531.1 - 0.012 15.3 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Acyltransferase Fasciclin PF02469.22 KFM22532.1 - 1.6e-09 38.1 0.0 3.4e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Fasciclin domain PAN_4 PF14295.6 KFM22532.1 - 6.6e-06 25.9 4.7 6.6e-06 25.9 4.7 2.5 3 0 0 3 3 3 1 PAN domain LRR_8 PF13855.6 KFM22533.1 - 1.1e-05 25.1 0.0 0.0073 16.1 0.0 2.2 1 1 2 3 3 3 2 Leucine rich repeat Fasciclin PF02469.22 KFM22535.1 - 1e-10 41.9 0.0 1.6e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Fasciclin domain PAN_4 PF14295.6 KFM22535.1 - 5.8e-08 32.5 4.5 1.3e-07 31.4 4.5 1.6 1 0 0 1 1 1 1 PAN domain VMA21 PF09446.10 KFM22535.1 - 0.071 13.2 0.0 0.2 11.8 0.0 1.8 1 0 0 1 1 1 0 VMA21-like domain zf_CCCH_4 PF18345.1 KFM22538.1 - 3.4e-05 23.7 0.1 3.4e-05 23.7 0.1 3.3 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_2 PF14608.6 KFM22538.1 - 0.0011 19.4 6.5 0.55 10.8 0.2 2.9 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH PF00642.24 KFM22538.1 - 0.0022 17.8 0.4 0.0022 17.8 0.4 2.8 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KFM22538.1 - 0.11 12.4 0.2 0.11 12.4 0.2 3.1 3 0 0 3 3 3 0 CCCH-type zinc finger Ribosom_S12_S23 PF00164.25 KFM22542.1 - 3.1e-36 123.5 1.0 3.7e-36 123.2 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Oxidored_q4 PF00507.19 KFM22543.1 - 4.8e-39 132.5 3.1 4.8e-39 132.5 3.1 1.3 1 1 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 ATP-synt_A PF00119.20 KFM22544.1 - 7.8e-54 182.8 27.1 9.6e-54 182.5 27.1 1.1 1 0 0 1 1 1 1 ATP synthase A chain Cytochrome_B PF00033.19 KFM22545.1 - 4.9e-85 284.1 18.9 9.4e-85 283.2 18.9 1.5 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 KFM22545.1 - 6.8e-45 153.1 12.5 6.8e-45 153.1 12.5 1.7 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 KFM22545.1 - 1e-34 118.9 1.8 1e-34 118.9 1.8 3.2 2 1 0 3 3 3 1 Cytochrome b(C-terminal)/b6/petD DUF973 PF06157.11 KFM22545.1 - 0.026 13.6 0.8 0.053 12.6 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF973) Ribosomal_L6 PF00347.23 KFM22546.1 - 2.7e-10 40.8 0.0 1.7e-07 31.8 0.0 2.8 2 1 0 2 2 2 2 Ribosomal protein L6 MULE PF10551.9 KFM22548.1 - 1.3e-11 44.7 0.2 2.4e-11 43.9 0.2 1.5 1 0 0 1 1 1 1 MULE transposase domain DUF5575 PF17738.1 KFM22548.1 - 0.034 13.2 0.0 0.07 12.2 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5575) Histone PF00125.24 KFM22549.1 - 6.2e-47 159.2 0.5 6.6e-47 159.1 0.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KFM22549.1 - 0.00012 22.4 0.0 0.00017 21.9 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KFM22549.1 - 0.00015 21.8 0.1 0.0002 21.4 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KFM22549.1 - 0.0012 19.1 0.1 0.0017 18.6 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KFM22549.1 - 0.008 16.2 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit PRAI PF00697.22 KFM22549.1 - 0.13 12.1 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase RVP PF00077.20 KFM22551.1 - 0.18 12.2 0.0 0.2 12.0 0.0 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease FLYWCH PF04500.16 KFM22555.1 - 0.18 11.9 0.5 0.45 10.7 0.1 1.8 2 0 0 2 2 2 0 FLYWCH zinc finger domain PKD PF00801.20 KFM22555.1 - 0.47 10.3 10.2 2 8.3 1.0 3.8 2 1 1 3 3 3 0 PKD domain AFG1_ATPase PF03969.16 KFM22557.1 - 1e-42 146.3 0.1 3.6e-42 144.5 0.1 1.8 1 1 0 1 1 1 1 AFG1-like ATPase Bac_DnaA PF00308.18 KFM22557.1 - 0.012 15.5 0.0 0.018 14.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial dnaA protein AAA PF00004.29 KFM22557.1 - 0.015 15.7 0.0 0.17 12.3 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KFM22557.1 - 0.11 12.4 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF2076 PF09849.9 KFM22557.1 - 0.36 10.8 1.0 0.52 10.3 0.1 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) AFG1_ATPase PF03969.16 KFM22558.1 - 3.5e-30 105.1 0.1 1.1e-25 90.3 0.0 2.0 2 0 0 2 2 2 2 AFG1-like ATPase DUF2946 PF11162.8 KFM22558.1 - 0.037 14.7 0.6 0.083 13.6 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) Golgin_A5 PF09787.9 KFM22559.1 - 0.02 14.4 6.7 0.029 13.8 6.7 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 GAS PF13851.6 KFM22559.1 - 0.09 12.1 12.3 0.11 11.8 12.3 1.0 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding VPS38 PF17649.1 KFM22559.1 - 0.34 9.7 2.6 0.39 9.5 2.6 1.0 1 0 0 1 1 1 0 Vacuolar protein sorting 38 APG6_N PF17675.1 KFM22559.1 - 0.77 10.3 17.5 2.1 8.9 17.1 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region YabA PF06156.13 KFM22559.1 - 6.3 7.5 9.0 62 4.3 8.6 1.9 1 1 1 2 2 2 0 Initiation control protein YabA RPN7 PF10602.9 KFM22560.1 - 2.3e-23 82.8 3.9 3.2e-21 75.8 0.5 2.8 2 1 1 3 3 3 2 26S proteasome subunit RPN7 PCI PF01399.27 KFM22560.1 - 7.7e-15 55.3 0.0 1.3e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 PCI domain DUF3631 PF12307.8 KFM22560.1 - 0.0037 17.5 0.6 0.006 16.8 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3631) CSN8_PSD8_EIF3K PF10075.9 KFM22560.1 - 0.061 13.3 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family FeoC PF09012.10 KFM22560.1 - 0.075 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 FeoC like transcriptional regulator Rad51 PF08423.11 KFM22561.1 - 1.7e-09 37.3 0.1 4.4e-09 36.0 0.1 1.8 1 1 0 1 1 1 1 Rad51 RecA PF00154.21 KFM22561.1 - 5.6e-06 26.0 0.0 9.4e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein DnaB_C PF03796.15 KFM22561.1 - 5.5e-05 22.6 0.0 0.00051 19.5 0.0 1.9 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain ATPase PF06745.13 KFM22561.1 - 5.8e-05 22.6 0.0 8.2e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.6 KFM22561.1 - 0.00018 21.2 1.0 0.00062 19.4 1.0 1.8 1 1 0 1 1 1 1 AAA domain SNF2_N PF00176.23 KFM22562.1 - 6.5e-40 136.9 0.0 4.6e-39 134.1 0.0 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain DUF1604 PF07713.13 KFM22562.1 - 6.3e-32 109.3 1.1 1.7e-31 107.9 1.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1604) Helicase_C PF00271.31 KFM22562.1 - 1.3e-13 51.2 0.0 2.2e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM22562.1 - 2.2e-07 31.0 0.0 4e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit G-patch PF01585.23 KFM22562.1 - 3.7e-05 23.5 0.6 3.7e-05 23.5 0.6 1.9 2 0 0 2 2 2 1 G-patch domain Surp PF01805.20 KFM22562.1 - 0.00036 20.5 0.0 0.00069 19.6 0.0 1.5 1 0 0 1 1 1 1 Surp module AAA_34 PF13872.6 KFM22562.1 - 0.0041 16.0 0.0 0.0073 15.2 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Pex14_N PF04695.13 KFM22563.1 - 0.52 11.0 3.6 0.96 10.1 2.0 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CAP_N PF01213.19 KFM22563.1 - 0.7 9.3 15.7 4.2 6.8 0.4 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 KFM22563.1 - 1.6 8.7 11.3 20 5.2 7.9 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator S4 PF01479.25 KFM22564.1 - 9.4e-12 44.5 0.1 1.5e-11 43.8 0.1 1.3 1 0 0 1 1 1 1 S4 domain DUF1062 PF06353.12 KFM22564.1 - 0.0029 18.4 0.0 0.0049 17.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1062) Med6 PF04934.14 KFM22566.1 - 9.1e-30 103.2 0.0 1.4e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component SET PF00856.28 KFM22567.1 - 0.00014 22.3 0.0 0.00026 21.4 0.0 1.5 1 0 0 1 1 1 1 SET domain VbhA PF18495.1 KFM22567.1 - 0.09 12.7 1.8 0.21 11.5 1.0 2.1 2 0 0 2 2 2 0 Antitoxin VbhA Hist_deacetyl PF00850.19 KFM22568.1 - 4.5e-43 147.9 0.0 1.8e-35 122.9 0.0 2.1 1 1 1 2 2 2 2 Histone deacetylase domain Ribosomal_S11 PF00411.19 KFM22569.1 - 4.5e-47 159.0 0.5 5.5e-47 158.7 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 KFM22569.1 - 0.15 12.3 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) DUF676 PF05057.14 KFM22570.1 - 1e-34 119.9 0.0 2.1e-33 115.7 0.0 2.0 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KFM22570.1 - 1.2e-06 28.4 0.0 2.4e-06 27.4 0.0 1.4 1 1 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 KFM22570.1 - 0.0073 16.2 0.0 0.0097 15.8 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Hydrolase_4 PF12146.8 KFM22570.1 - 0.013 14.8 0.1 0.032 13.5 0.0 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFM22570.1 - 0.019 14.7 0.1 0.54 9.8 0.0 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 KFM22570.1 - 0.019 14.9 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF3958 PF13125.6 KFM22570.1 - 0.08 13.2 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3958) Lipase_2 PF01674.18 KFM22570.1 - 0.18 11.3 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 2) HEAT_2 PF13646.6 KFM22572.1 - 9.8e-11 41.9 33.6 1.5e-07 31.7 6.9 3.0 1 1 2 3 3 3 3 HEAT repeats Arm PF00514.23 KFM22572.1 - 1e-05 25.4 1.6 1.4 9.1 0.3 3.8 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KFM22572.1 - 2.5e-05 24.2 10.0 0.01 16.0 0.1 4.1 4 0 0 4 4 4 2 HEAT repeat DUF4042 PF13251.6 KFM22572.1 - 0.0012 18.6 0.9 0.36 10.5 0.1 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4042) HEAT_EZ PF13513.6 KFM22572.1 - 0.0087 16.5 13.7 0.26 11.9 0.0 3.7 3 0 0 3 3 3 2 HEAT-like repeat Cnd1 PF12717.7 KFM22572.1 - 0.024 14.7 0.0 0.047 13.7 0.0 1.4 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KFM22572.1 - 0.024 13.2 0.0 0.11 11.0 0.0 1.7 1 1 0 1 1 1 0 Adaptin N terminal region SIL1 PF16782.5 KFM22572.1 - 0.034 13.4 0.0 0.047 12.9 0.0 1.1 1 0 0 1 1 1 0 Nucleotide exchange factor SIL1 Fes1 PF08609.10 KFM22572.1 - 0.35 11.8 2.3 12 6.8 0.4 2.8 2 1 0 2 2 2 0 Nucleotide exchange factor Fes1 CCB1 PF12046.8 KFM22573.1 - 5e-48 162.6 0.0 5.9e-48 162.4 0.0 1.0 1 0 0 1 1 1 1 Cofactor assembly of complex C subunit B LpxK PF02606.14 KFM22574.1 - 4.5e-31 108.2 0.1 1.4e-19 70.4 0.0 2.1 2 0 0 2 2 2 2 Tetraacyldisaccharide-1-P 4'-kinase Phage_tail_X PF05489.12 KFM22574.1 - 0.14 11.9 0.0 0.36 10.5 0.0 1.7 1 0 0 1 1 1 0 Phage Tail Protein X Amino_oxidase PF01593.24 KFM22577.1 - 5.5e-38 131.4 0.0 6.9e-38 131.1 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Romo1 PF10247.9 KFM22577.1 - 4.4e-20 71.8 4.2 8.6e-20 70.9 4.2 1.5 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 NAD_binding_8 PF13450.6 KFM22577.1 - 4.1e-16 59.0 0.1 1e-15 57.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KFM22577.1 - 2.7e-08 33.3 0.2 4.2e-08 32.7 0.2 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KFM22577.1 - 9.2e-08 32.0 0.5 2.2e-07 30.8 0.5 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFM22577.1 - 8e-05 22.0 0.0 0.00051 19.4 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFM22577.1 - 8.5e-05 21.4 0.2 0.00061 18.6 0.4 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 KFM22577.1 - 0.00025 20.4 0.5 0.00038 19.8 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KFM22577.1 - 0.0019 17.5 0.1 0.011 15.1 1.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KFM22577.1 - 0.0083 15.2 0.9 0.014 14.5 0.9 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KFM22577.1 - 0.0085 15.5 3.1 0.013 14.9 3.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KFM22577.1 - 0.01 15.0 0.2 0.12 11.4 0.3 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein Tim17 PF02466.19 KFM22577.1 - 0.011 16.1 2.7 0.033 14.6 2.7 1.8 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Pyr_redox PF00070.27 KFM22577.1 - 0.011 16.2 0.4 0.031 14.9 0.4 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFM22577.1 - 0.024 13.9 0.0 0.048 12.9 0.0 1.5 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 KFM22577.1 - 0.031 13.6 0.5 0.053 12.8 0.5 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF2924 PF11149.8 KFM22578.1 - 0.025 15.0 0.1 0.047 14.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2924) Cnd1 PF12717.7 KFM22581.1 - 1.3e-47 161.9 0.6 1.9e-45 154.8 0.0 3.6 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 KFM22581.1 - 2.6e-12 46.9 0.0 7e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term Adaptin_N PF01602.20 KFM22581.1 - 0.001 17.7 0.1 0.009 14.6 0.1 2.4 2 1 0 2 2 2 1 Adaptin N terminal region HEAT PF02985.22 KFM22581.1 - 0.0012 18.9 12.5 16 6.1 0.0 7.7 8 0 0 8 8 8 2 HEAT repeat Cnd3 PF12719.7 KFM22581.1 - 0.021 14.0 0.2 0.05 12.8 0.2 1.6 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain RTP1_C1 PF10363.9 KFM22581.1 - 0.12 12.6 0.4 5.6 7.2 0.1 3.5 3 1 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 KFM22581.1 - 8.4 7.0 15.0 15 6.2 0.1 6.0 5 0 0 5 5 5 0 HEAT-like repeat ACBP PF00887.19 KFM22582.1 - 1.4e-13 50.9 2.3 1.9e-13 50.4 0.1 2.0 2 0 0 2 2 2 1 Acyl CoA binding protein ParA PF10609.9 KFM22583.1 - 1.4e-88 296.5 0.1 4.5e-88 294.8 0.1 1.6 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KFM22583.1 - 1.1e-14 54.6 0.0 1.7e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KFM22583.1 - 9.6e-09 35.4 0.1 7.2e-08 32.5 0.3 1.9 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 KFM22583.1 - 8.8e-07 28.5 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.18 KFM22583.1 - 2.1e-06 27.4 0.0 0.0073 15.8 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.6 KFM22583.1 - 1.1e-05 25.1 0.1 1.9e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 KFM22583.1 - 0.0015 17.8 0.5 0.003 16.8 0.5 1.4 1 0 0 1 1 1 1 Anion-transporting ATPase VirC1 PF07015.11 KFM22583.1 - 0.04 13.2 0.1 0.062 12.6 0.1 1.2 1 0 0 1 1 1 0 VirC1 protein SRP54 PF00448.22 KFM22583.1 - 0.22 11.1 0.1 0.35 10.5 0.1 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain FTHFS PF01268.19 KFM22583.1 - 0.54 8.4 1.3 0.78 7.9 1.3 1.1 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase FMN_red PF03358.15 KFM22584.1 - 4.9e-29 101.1 0.1 9e-09 35.3 0.0 3.5 3 0 0 3 3 3 3 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KFM22584.1 - 1.3e-19 70.7 0.0 5.5e-05 23.0 0.0 3.3 3 0 0 3 3 3 3 Flavodoxin-like fold Flavodoxin_1 PF00258.25 KFM22584.1 - 0.00077 19.7 0.1 1 9.5 0.0 4.1 3 2 0 3 3 3 1 Flavodoxin CENP-F_C_Rb_bdg PF10490.9 KFM22584.1 - 0.041 13.3 0.0 17 4.9 0.0 3.1 3 0 0 3 3 3 0 Rb-binding domain of kinetochore protein Cenp-F/LEK1 Herpes_pp38 PF04846.13 KFM22584.1 - 0.52 10.3 2.5 77 3.3 0.1 3.3 3 0 0 3 3 3 0 Herpesvirus pp38 phosphoprotein Sugar_tr PF00083.24 KFM22585.1 - 6.9e-67 226.3 21.1 1e-66 225.7 21.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter SNARE_assoc PF09335.11 KFM22585.1 - 8.6e-21 74.6 4.4 8.6e-21 74.6 4.4 3.9 3 1 0 3 3 2 1 SNARE associated Golgi protein MFS_1 PF07690.16 KFM22585.1 - 1.4e-19 70.3 31.9 1.4e-19 70.3 31.9 3.2 1 1 2 3 3 2 1 Major Facilitator Superfamily Thioredoxin PF00085.20 KFM22585.1 - 1.5e-17 63.5 0.0 2.2e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KFM22585.1 - 6e-06 26.7 0.0 1.5e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KFM22585.1 - 0.00028 21.0 0.0 0.0006 19.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 KFM22585.1 - 0.001 19.0 0.0 0.0015 18.4 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Redoxin PF08534.10 KFM22585.1 - 0.014 15.1 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 Redoxin TMEM65 PF10507.9 KFM22585.1 - 0.03 14.3 0.5 0.16 12.0 0.0 2.4 2 0 0 2 2 2 0 Transmembrane protein 65 Thioredoxin_8 PF13905.6 KFM22585.1 - 0.054 13.8 0.0 0.34 11.3 0.0 2.0 1 1 0 1 1 1 0 Thioredoxin-like OST3_OST6 PF04756.13 KFM22585.1 - 0.29 10.4 1.0 1.5 8.1 0.0 2.6 3 0 0 3 3 3 0 OST3 / OST6 family, transporter family NopRA1 PF16201.5 KFM22587.1 - 4.4e-23 81.9 0.0 8.6e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 Npa1 PF11707.8 KFM22587.1 - 2.7e-14 53.3 0.0 3.8e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal Npa1 PF11707.8 KFM22589.1 - 1e-10 41.5 0.4 1.3e-10 41.2 0.4 1.1 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal Glyco_hydro_127 PF07944.12 KFM22590.1 - 6.7e-22 77.7 0.0 7.8e-22 77.4 0.0 1.0 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 DUF3921 PF13060.6 KFM22590.1 - 0.091 12.8 0.2 2.7 8.1 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3921) Glyco_hydro_127 PF07944.12 KFM22591.1 - 1.3e-30 106.4 0.0 3.6e-30 105.0 0.0 1.6 1 1 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_127 PF07944.12 KFM22592.1 - 1.7e-11 43.3 0.0 2.2e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 GTP_EFTU PF00009.27 KFM22593.1 - 4.3e-51 173.2 0.0 6e-51 172.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 KFM22593.1 - 5.5e-44 148.7 0.1 8.8e-44 148.1 0.1 1.3 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 KFM22593.1 - 2.4e-16 59.5 0.0 4.9e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.23 KFM22593.1 - 5e-06 26.6 0.0 8.3e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 KFM22593.1 - 0.0005 20.4 0.0 0.0016 18.8 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ras PF00071.22 KFM22593.1 - 0.0019 17.8 0.0 0.0032 17.1 0.0 1.3 1 0 0 1 1 1 1 Ras family EFG_II PF14492.6 KFM22593.1 - 0.0059 16.7 0.0 0.028 14.5 0.0 2.1 1 1 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.10 KFM22593.1 - 0.0085 15.5 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RF3_C PF16658.5 KFM22593.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 KFM22593.1 - 0.22 10.8 0.0 0.41 9.9 0.0 1.3 1 0 0 1 1 1 0 Septin GYF_2 PF14237.6 KFM22594.1 - 1.2e-13 50.6 0.1 2.3e-13 49.7 0.1 1.5 1 0 0 1 1 1 1 GYF domain 2 Lipase_3 PF01764.25 KFM22595.1 - 1.3e-27 96.4 0.0 1.7e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.20 KFM22595.1 - 0.00085 19.5 0.1 0.0013 18.8 0.1 1.2 1 0 0 1 1 1 1 Thioesterase domain DUF2974 PF11187.8 KFM22595.1 - 0.0066 16.0 1.7 1.5 8.3 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 KFM22595.1 - 0.042 14.4 13.7 0.023 15.3 11.1 1.9 1 1 1 2 2 2 0 Alpha/beta hydrolase family Pro_isomerase PF00160.21 KFM22597.1 - 7.6e-26 91.3 0.0 1.2e-25 90.6 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pkinase PF00069.25 KFM22598.1 - 4.4e-34 118.0 0.0 9.6e-34 116.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM22598.1 - 9.7e-15 54.5 0.0 1.4e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFM22598.1 - 0.0007 19.6 0.6 0.0025 17.8 0.0 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KFM22598.1 - 0.0055 16.1 0.0 0.0084 15.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFM22598.1 - 0.01 15.2 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 KFM22598.1 - 0.047 13.3 0.0 0.09 12.4 0.0 1.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Metal_resist PF13801.6 KFM22598.1 - 0.26 11.5 0.0 0.26 11.5 0.0 2.6 3 0 0 3 3 3 0 Heavy-metal resistance LsmAD PF06741.13 KFM22599.1 - 0.19 12.3 0.0 0.29 11.7 0.0 1.3 1 0 0 1 1 1 0 LsmAD domain Acetyltransf_1 PF00583.25 KFM22600.1 - 1.7e-12 47.6 0.0 2.2e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFM22600.1 - 7.8e-08 32.3 0.0 1.1e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFM22600.1 - 2.7e-07 30.5 0.2 3.9e-07 29.9 0.2 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KFM22600.1 - 3.3e-05 24.2 0.0 4.4e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KFM22600.1 - 0.029 14.5 0.0 0.04 14.0 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3506 PF12014.8 KFM22601.1 - 5.6e-16 58.8 0.0 1.8e-14 53.9 0.0 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3506) UVR PF02151.19 KFM22601.1 - 0.052 13.3 10.0 0.43 10.4 2.6 2.7 2 0 0 2 2 2 0 UvrB/uvrC motif Plus-3 PF03126.18 KFM22602.1 - 2e-24 86.2 0.0 4.3e-24 85.1 0.0 1.6 1 0 0 1 1 1 1 Plus-3 domain Hydrolase_4 PF12146.8 KFM22604.1 - 3.4e-17 62.5 0.0 1e-12 47.8 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFM22604.1 - 1.4e-11 44.6 0.0 1e-09 38.4 0.1 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold UIM PF02809.20 KFM22604.1 - 6.3e-07 28.9 13.6 0.00054 19.7 4.8 2.8 2 0 0 2 2 2 2 Ubiquitin interaction motif Abhydrolase_6 PF12697.7 KFM22604.1 - 1e-05 26.3 7.8 1.4e-05 25.8 7.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 KFM22604.1 - 3.8e-05 23.4 0.0 0.0012 18.5 0.0 2.1 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 KFM22604.1 - 0.0001 21.9 0.0 0.00056 19.4 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.13 KFM22604.1 - 0.0016 18.1 0.0 0.0027 17.4 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 KFM22604.1 - 0.011 15.3 0.0 0.28 10.7 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family LIP PF03583.14 KFM22604.1 - 0.086 12.2 0.0 0.2 11.0 0.1 1.5 2 0 0 2 2 2 0 Secretory lipase LRR_1 PF00560.33 KFM22605.1 - 0.0024 18.2 1.7 0.47 11.2 0.0 3.0 3 0 0 3 3 3 1 Leucine Rich Repeat LRR_6 PF13516.6 KFM22605.1 - 0.0072 16.3 0.1 5.8 7.2 0.0 2.5 2 0 0 2 2 2 2 Leucine Rich repeat LRR_4 PF12799.7 KFM22605.1 - 0.018 15.5 0.2 0.051 14.0 0.3 1.7 1 1 0 1 1 1 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFM22605.1 - 0.082 12.7 0.8 3.4 7.5 0.8 2.2 1 1 0 1 1 1 0 Leucine rich repeat LRR_8 PF13855.6 KFM22606.1 - 1.6e-06 27.7 0.6 0.00014 21.5 0.1 2.4 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KFM22606.1 - 1.1e-05 25.7 0.6 0.25 11.8 0.0 2.7 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFM22606.1 - 0.12 12.5 1.3 2.9 8.2 0.0 3.2 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 KFM22606.1 - 0.34 11.6 7.2 6.1 7.8 0.0 4.6 5 2 0 5 5 5 0 Leucine Rich Repeat LRRNT_2 PF08263.12 KFM22606.1 - 3.2 8.1 8.3 68 3.9 8.3 2.4 1 1 0 1 1 1 0 Leucine rich repeat N-terminal domain LRR_8 PF13855.6 KFM22607.1 - 6.3e-15 54.7 0.0 1.4e-06 28.0 0.0 2.4 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KFM22607.1 - 5e-11 42.7 0.0 0.0027 18.1 0.1 3.8 2 2 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM22607.1 - 2.7e-08 33.3 0.0 2.3 9.1 0.0 5.1 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_6 PF13516.6 KFM22607.1 - 7.2e-05 22.5 4.1 6.1 7.2 0.0 4.6 5 0 0 5 5 5 3 Leucine Rich repeat LRR_8 PF13855.6 KFM22608.1 - 3.6e-19 68.3 5.8 1.4e-06 28.0 0.1 3.3 3 0 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFM22608.1 - 7.2e-09 35.8 9.2 0.00056 20.2 1.2 3.8 2 1 5 7 7 7 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM22608.1 - 3.2e-05 23.9 10.4 8 7.4 0.1 6.0 6 1 1 7 7 7 3 Leucine Rich Repeat LRRNT_2 PF08263.12 KFM22608.1 - 0.0017 18.6 4.3 0.0017 18.6 4.3 2.6 2 1 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 KFM22608.1 - 0.29 11.3 9.8 2.8 8.2 0.1 4.9 7 0 0 7 7 7 0 Leucine Rich repeat PP2C PF00481.21 KFM22609.1 - 2.8e-59 200.9 0.0 3.3e-59 200.6 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KFM22609.1 - 0.0012 18.5 0.3 0.0072 16.0 0.3 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C TauE PF01925.19 KFM22610.1 - 3.7e-26 92.2 40.1 1.5e-13 51.0 21.4 2.4 2 1 0 2 2 2 2 Sulfite exporter TauE/SafE CBM_48 PF02922.18 KFM22611.1 - 5.7e-15 55.5 0.0 1.2e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 KFM22611.1 - 1.5e-12 47.8 0.1 4.9e-07 29.6 0.0 3.6 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 KFM22611.1 - 0.00069 20.0 0.0 0.0018 18.7 0.0 1.6 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain BOP1NT PF08145.12 KFM22612.1 - 1.9e-91 306.6 0.1 3.1e-91 305.9 0.1 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 KFM22612.1 - 3.8e-21 75.0 0.1 2.7e-07 31.1 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM22612.1 - 6.6e-07 29.5 0.0 0.89 9.9 0.0 4.0 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 KFM22612.1 - 0.00023 19.7 0.0 0.15 10.4 0.0 2.2 1 1 1 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz DARPP-32 PF05395.12 KFM22613.1 - 0.14 12.4 1.0 0.24 11.6 1.0 1.4 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 Pkinase PF00069.25 KFM22614.1 - 8.8e-65 218.7 0.0 1e-64 218.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM22614.1 - 1.5e-28 99.9 0.0 1.8e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM22614.1 - 0.0058 16.0 0.0 0.37 10.1 0.0 2.1 1 1 1 2 2 2 2 Kinase-like Pkinase PF00069.25 KFM22615.1 - 1.7e-64 217.7 0.0 2.3e-64 217.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM22615.1 - 3.2e-27 95.5 0.0 4.4e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase CbiQ PF02361.16 KFM22615.1 - 1.5e-07 31.3 6.6 6.5e-06 25.9 6.6 2.1 1 1 0 1 1 1 1 Cobalt transport protein PAP_fibrillin PF04755.12 KFM22616.1 - 0.00011 22.2 0.0 0.0033 17.4 0.0 2.2 1 1 0 1 1 1 1 PAP_fibrillin Pkinase PF00069.25 KFM22617.1 - 3e-51 174.3 0.0 3.9e-51 173.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM22617.1 - 4.7e-37 127.7 0.0 7.2e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM22617.1 - 0.15 11.4 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like RNA_pol_3_Rpc31 PF11705.8 KFM22619.1 - 0.00019 21.7 1.5 0.00031 21.1 1.3 1.4 1 1 1 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 Peptidase_S9 PF00326.21 KFM22620.1 - 6.2e-33 114.1 0.0 8.5e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 KFM22620.1 - 4e-17 62.1 0.0 4.8e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Hydrolase_4 PF12146.8 KFM22620.1 - 1.6e-09 37.4 0.6 2.7e-09 36.7 0.6 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFM22620.1 - 0.018 14.7 0.1 0.03 14.0 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KFM22620.1 - 0.054 13.4 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold SWIB PF02201.18 KFM22621.1 - 3.5e-11 42.8 0.0 6.6e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain RGP PF03214.13 KFM22622.1 - 4.7e-161 535.7 0.0 5.3e-161 535.5 0.0 1.0 1 0 0 1 1 1 1 Reversibly glycosylated polypeptide NUC153 PF08159.12 KFM22623.1 - 2e-10 40.3 7.8 7e-06 25.8 0.0 3.5 3 0 0 3 3 3 3 NUC153 domain OST3_OST6 PF04756.13 KFM22624.1 - 1.6e-39 136.0 0.0 1.8e-39 135.8 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family ATP-synt_J PF04911.12 KFM22624.1 - 0.11 12.1 1.6 0.2 11.3 0.3 1.9 1 1 1 2 2 2 0 ATP synthase j chain Prok-JAB PF14464.6 KFM22625.1 - 1.5e-11 44.1 0.2 3.4e-11 43.0 0.2 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain JAB PF01398.21 KFM22625.1 - 1e-08 35.1 0.0 1.7e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Myb_DNA-binding PF00249.31 KFM22625.1 - 3.3e-07 30.4 0.1 7.5e-07 29.2 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain ubiquitin PF00240.23 KFM22627.1 - 2.2e-17 62.6 0.0 4.4e-10 39.2 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin family Ubiquitin_2 PF14560.6 KFM22627.1 - 0.023 15.2 0.0 0.072 13.6 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-like domain Rad60-SLD PF11976.8 KFM22627.1 - 0.043 13.7 0.0 0.23 11.3 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Rab3-GTPase_cat PF13890.6 KFM22628.1 - 1.4e-08 34.6 0.0 3e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Rab3 GTPase-activating protein catalytic subunit SET PF00856.28 KFM22631.1 - 0.001 19.5 0.0 0.0019 18.6 0.0 1.5 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 KFM22631.1 - 0.096 13.4 0.0 0.26 12.0 0.0 1.7 1 1 0 1 1 1 0 Rubisco LSMT substrate-binding Cellulase PF00150.18 KFM22632.1 - 2.7e-16 59.8 0.1 4e-16 59.3 0.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PAN_1 PF00024.26 KFM22632.1 - 1.3e-08 34.7 0.2 3.3e-08 33.4 0.2 1.6 1 0 0 1 1 1 1 PAN domain EGF_CA PF07645.15 KFM22632.1 - 1.5e-07 31.5 6.9 4.1e-07 30.1 6.9 1.8 1 0 0 1 1 1 1 Calcium-binding EGF domain PAN_4 PF14295.6 KFM22632.1 - 3.4e-05 23.6 1.8 9.3e-05 22.3 1.8 1.7 1 0 0 1 1 1 1 PAN domain EGF_3 PF12947.7 KFM22632.1 - 0.00013 22.1 11.6 0.00034 20.7 11.6 1.8 1 0 0 1 1 1 1 EGF domain DUF4038 PF13204.6 KFM22632.1 - 0.01 15.5 0.2 0.016 14.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4038) PAN_2 PF08276.11 KFM22632.1 - 0.015 15.4 0.5 0.05 13.7 0.5 1.9 1 0 0 1 1 1 0 PAN-like domain EGF PF00008.27 KFM22632.1 - 0.057 13.7 7.2 0.15 12.4 7.2 1.8 1 0 0 1 1 1 0 EGF-like domain EGF_MSP1_1 PF12946.7 KFM22632.1 - 0.063 13.3 2.9 0.15 12.1 2.9 1.7 1 0 0 1 1 1 0 MSP1 EGF domain 1 FXa_inhibition PF14670.6 KFM22632.1 - 0.088 13.1 8.6 0.25 11.6 8.6 1.8 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site hEGF PF12661.7 KFM22632.1 - 0.16 12.6 2.2 0.71 10.6 2.2 2.2 1 0 0 1 1 1 0 Human growth factor-like EGF DUF4074 PF13293.6 KFM22632.1 - 0.19 12.0 1.7 0.5 10.7 1.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4074) NAP PF00956.18 KFM22633.1 - 0.52 9.4 3.9 0.83 8.8 3.9 1.2 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) DUF2362 PF10154.9 KFM22633.1 - 0.77 8.6 3.1 0.99 8.3 3.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) GATA PF00320.27 KFM22634.1 - 1.3e-11 43.9 1.4 1.3e-11 43.9 1.4 2.3 3 0 0 3 3 3 1 GATA zinc finger OrfB_Zn_ribbon PF07282.11 KFM22634.1 - 2.7 8.0 7.0 0.11 12.4 1.3 1.6 2 0 0 2 2 2 0 Putative transposase DNA-binding domain MSA-2c PF12238.8 KFM22634.1 - 8.2 6.4 8.5 13 5.7 8.5 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c FtsJ PF01728.19 KFM22636.1 - 6.9e-39 133.8 0.0 8.4e-39 133.5 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase FtsJ PF01728.19 KFM22637.1 - 3e-17 63.3 0.0 3.6e-17 63.0 0.0 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase CGI-121 PF08617.10 KFM22638.1 - 7.6e-17 61.9 0.8 1.3e-15 57.9 0.3 2.0 1 1 1 2 2 2 2 Kinase binding protein CGI-121 Rhomboid PF01694.22 KFM22639.1 - 8.7e-26 90.7 8.9 1.3e-25 90.2 8.9 1.2 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 KFM22639.1 - 0.061 13.9 0.0 0.16 12.6 0.0 1.6 2 0 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) DUF829 PF05705.14 KFM22640.1 - 2.7e-28 99.5 0.0 4.4e-28 98.8 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Pkinase PF00069.25 KFM22641.1 - 2.2e-17 63.3 0.0 8.6e-12 45.0 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFM22641.1 - 7.5e-16 58.2 0.0 3e-09 36.6 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Tubulin PF00091.25 KFM22642.1 - 1.8e-69 233.9 0.0 2.6e-69 233.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFM22642.1 - 1e-41 142.0 0.0 1.5e-41 141.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KFM22642.1 - 5.3e-05 23.5 0.0 0.00014 22.1 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 KFM22642.1 - 0.002 17.4 0.1 0.013 14.7 0.0 1.9 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 KFM22642.1 - 0.005 16.5 0.0 0.0092 15.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain PP2C PF00481.21 KFM22643.1 - 3.6e-29 102.2 0.0 5.5e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C GCP_C_terminal PF04130.13 KFM22643.1 - 3.4e-15 56.3 0.0 5.7e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal DnaJ PF00226.31 KFM22645.1 - 1.6e-05 24.9 0.0 2.8e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain zf-RING_2 PF13639.6 KFM22646.1 - 1.5e-10 41.2 7.0 2.2e-10 40.7 7.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KFM22646.1 - 1e-08 34.7 3.8 1.8e-08 34.0 3.8 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 KFM22646.1 - 9.4e-07 29.0 7.6 2.2e-06 27.9 7.6 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KFM22646.1 - 1.7e-06 27.8 4.5 2.5e-06 27.2 4.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KFM22646.1 - 2.1e-05 24.5 2.1 4.2e-05 23.5 2.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KFM22646.1 - 0.00062 19.7 5.0 0.00096 19.1 5.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFM22646.1 - 0.00064 19.5 7.7 0.0015 18.3 7.7 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFM22646.1 - 0.0026 17.7 6.8 0.0044 17.0 6.8 1.4 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KFM22646.1 - 0.0048 16.5 4.0 0.0093 15.6 4.0 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 KFM22646.1 - 0.012 15.5 4.7 0.018 14.9 4.7 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KFM22646.1 - 0.15 12.3 8.3 0.5 10.6 8.3 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 KFM22646.1 - 0.36 11.0 6.0 0.77 9.9 5.4 1.8 1 1 1 2 2 2 0 RING-variant domain zf-C3HC4_5 PF17121.5 KFM22646.1 - 5.3 7.0 7.7 32 4.5 7.7 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) YgbB PF02542.16 KFM22647.1 - 2.6e-62 209.7 0.0 2.9e-62 209.5 0.0 1.0 1 0 0 1 1 1 1 YgbB family CSD PF00313.22 KFM22649.1 - 1e-16 60.6 0.5 1.6e-09 37.5 0.0 3.7 4 0 0 4 4 4 3 'Cold-shock' DNA-binding domain PWWP PF00855.17 KFM22650.1 - 3.2e-14 53.1 0.9 3.7e-14 52.9 0.1 1.5 2 0 0 2 2 2 1 PWWP domain DUF1744 PF08490.12 KFM22652.1 - 3.1e-91 305.9 0.0 4.2e-90 302.2 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 KFM22652.1 - 1.1e-74 251.6 0.0 1.7e-74 251.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 KFM22652.1 - 1.7e-14 53.4 0.0 2.7e-13 49.4 0.0 2.4 2 1 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 KFM22652.1 - 2.8e-08 33.7 0.2 1.1e-07 31.8 0.1 1.9 2 0 0 2 2 2 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 KFM22652.1 - 7.8e-07 29.2 0.0 3.7e-06 27.0 0.0 2.1 1 1 0 1 1 1 1 RNase_H superfamily Ku PF02735.16 KFM22653.1 - 6.7e-27 94.5 0.0 1e-26 93.9 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain SAP PF02037.27 KFM22653.1 - 2.2e-06 27.3 0.0 3.4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 SAP domain Ku_C PF03730.14 KFM22653.1 - 0.11 13.2 0.0 0.22 12.2 0.0 1.4 1 0 0 1 1 1 0 Ku70/Ku80 C-terminal arm Ku_N PF03731.15 KFM22654.1 - 5.3e-10 39.4 0.0 6.7e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Glucan_synthase PF02364.15 KFM22655.1 - 1.7e-146 489.7 4.9 1.8e-126 423.4 5.5 3.8 1 1 1 2 2 2 2 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KFM22655.1 - 6.3e-11 42.7 0.2 4.2e-09 36.8 0.2 2.3 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 DnaJ_CXXCXGXG PF00684.19 KFM22657.1 - 0.048 14.0 4.7 0.89 10.0 5.0 2.0 1 1 1 2 2 2 0 DnaJ central domain Anti-TRAP PF15777.5 KFM22657.1 - 0.28 11.2 2.7 4.4 7.3 2.7 2.1 1 1 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein Apolipoprotein PF01442.18 KFM22659.1 - 0.12 12.2 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain HTH_3 PF01381.22 KFM22660.1 - 8.3e-16 57.8 0.6 1.1e-15 57.4 0.6 1.2 1 0 0 1 1 1 1 Helix-turn-helix MBF1 PF08523.10 KFM22660.1 - 8.4e-08 32.6 0.6 8.4e-08 32.6 0.6 2.2 2 1 1 3 3 3 1 Multiprotein bridging factor 1 HTH_31 PF13560.6 KFM22660.1 - 5.1e-06 26.7 0.0 7.3e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 KFM22660.1 - 1.6e-05 24.8 0.2 2.3e-05 24.3 0.2 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain CompInhib_SCIN PF11546.8 KFM22660.1 - 0.015 15.4 0.2 0.018 15.1 0.2 1.2 1 0 0 1 1 1 0 Staphylococcal complement inhibitor SCIN HTH_25 PF13413.6 KFM22660.1 - 0.022 14.6 0.2 0.039 13.8 0.2 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_38 PF13936.6 KFM22660.1 - 0.033 14.0 0.1 0.06 13.1 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain MqsA_antitoxin PF15731.5 KFM22660.1 - 0.095 12.8 0.1 0.11 12.7 0.1 1.1 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA Pkinase PF00069.25 KFM22661.1 - 5e-20 72.0 0.6 3.4e-18 66.0 0.0 3.1 4 0 0 4 4 4 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM22661.1 - 7.1e-10 38.6 0.0 4.7e-07 29.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KFM22661.1 - 4.8e-08 33.2 0.0 9.5e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KFM22661.1 - 0.00025 20.7 0.0 0.00046 19.9 0.0 1.4 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KFM22661.1 - 0.0012 18.3 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFM22661.1 - 0.0021 16.9 1.0 0.0029 16.4 1.0 1.5 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFM22661.1 - 0.0071 15.7 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KFM22661.1 - 0.024 13.7 0.0 0.038 13.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 KFM22661.1 - 0.098 11.6 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain zf-A20 PF01754.16 KFM22662.1 - 0.15 12.0 0.1 0.43 10.6 0.1 1.8 1 0 0 1 1 1 0 A20-like zinc finger DUF3645 PF12359.8 KFM22664.1 - 0.14 11.5 0.4 2.2 7.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3645) Trypsin PF00089.26 KFM22665.1 - 0.031 14.1 0.1 0.22 11.3 0.0 2.1 1 1 1 2 2 2 0 Trypsin Flu_C_NS1 PF03506.13 KFM22666.1 - 0.12 12.3 0.1 0.2 11.6 0.1 1.3 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Cadherin_tail PF15974.5 KFM22666.1 - 0.24 11.7 0.8 0.46 10.8 0.4 1.7 1 1 1 2 2 2 0 Cadherin C-terminal cytoplasmic tail, catenin-binding region Lactamase_B_6 PF16661.5 KFM22668.1 - 6e-29 100.9 0.0 1.3e-13 50.9 0.0 3.4 3 0 0 3 3 3 2 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 KFM22668.1 - 1.1e-25 90.0 0.0 1.9e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 KFM22668.1 - 5.4e-24 85.3 6.0 2.1e-12 47.5 1.0 3.5 2 2 0 2 2 2 2 Metallo-beta-lactamase superfamily CPSF73-100_C PF11718.8 KFM22668.1 - 5.3e-18 65.3 0.0 8.3e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Lactamase_B_2 PF12706.7 KFM22668.1 - 5.3e-09 35.9 3.0 0.00025 20.6 0.2 3.6 2 2 0 2 2 2 2 Beta-lactamase superfamily domain RMMBL PF07521.12 KFM22668.1 - 6.3e-09 35.6 0.0 1.3e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Beta_lactamase3 PF17030.5 KFM22668.1 - 8.5e-08 31.7 0.0 0.012 14.9 0.0 2.1 2 0 0 2 2 2 2 Putative beta-lactamase-like family Lactamase_B_3 PF13483.6 KFM22668.1 - 1.1e-07 31.9 0.0 0.0075 16.2 0.0 3.6 2 2 0 2 2 2 2 Beta-lactamase superfamily domain Wound_ind PF08186.11 KFM22668.1 - 0.16 12.4 0.0 36 4.9 0.0 2.3 2 0 0 2 2 2 0 Wound-inducible basic protein family PhoLip_ATPase_C PF16212.5 KFM22669.1 - 3.9e-61 207.0 20.5 3.9e-61 207.0 20.5 3.2 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFM22669.1 - 8.5e-17 60.6 0.0 8.5e-17 60.6 0.0 2.5 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KFM22669.1 - 6.4e-14 52.7 0.0 0.00011 22.6 0.0 4.5 4 0 0 4 4 4 4 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KFM22669.1 - 1.9e-09 37.7 0.0 0.0028 17.4 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KFM22669.1 - 1.4e-06 27.9 0.1 1.9e-05 24.3 0.0 2.8 2 1 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 KFM22669.1 - 3.8e-06 26.9 0.0 2.9e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) HAD PF12710.7 KFM22669.1 - 0.0022 18.4 0.1 16 5.8 0.0 3.5 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Peptidase_M16_M PF16187.5 KFM22670.1 - 2e-71 240.5 0.0 3.7e-71 239.7 0.0 1.4 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 KFM22670.1 - 7.2e-30 103.9 0.0 1.6e-29 102.8 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KFM22670.1 - 3.6e-25 89.1 0.0 7.3e-14 52.2 0.0 3.7 4 0 0 4 4 4 2 Peptidase M16 inactive domain AF-4 PF05110.13 KFM22670.1 - 0.33 9.0 4.6 0.45 8.6 4.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Glyco_hydro_20 PF00728.22 KFM22671.1 - 4.1e-65 220.5 0.0 5.1e-65 220.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain E2F_TDP PF02319.20 KFM22672.1 - 2.7e-20 72.2 0.0 4.1e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain E2F_CC-MB PF16421.5 KFM22672.1 - 7.9e-06 26.2 0.0 1.1e-05 25.7 0.0 1.2 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain TrmB PF01978.19 KFM22672.1 - 0.024 14.5 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Methyltransf_33 PF10017.9 KFM22674.1 - 1.6e-74 250.9 0.0 2.4e-74 250.3 0.0 1.1 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 KFM22674.1 - 2.5e-16 60.0 1.3 1.2e-09 38.1 1.0 2.4 2 1 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 KFM22674.1 - 3.6e-05 24.3 9.0 4.2e-05 24.1 6.2 2.6 2 1 0 2 2 2 1 DinB superfamily Methyltransf_25 PF13649.6 KFM22674.1 - 0.00096 19.8 0.0 0.003 18.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM22674.1 - 0.023 15.4 0.0 0.045 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KFM22674.1 - 0.062 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_77 PF02446.17 KFM22675.1 - 9.9e-139 463.2 0.3 2.2e-87 293.9 0.2 2.0 2 0 0 2 2 2 2 4-alpha-glucanotransferase CBM_20 PF00686.19 KFM22675.1 - 3.6e-18 65.3 0.0 1.1e-11 44.5 0.0 2.4 2 0 0 2 2 2 2 Starch binding domain Tom37 PF10568.9 KFM22676.1 - 6.2e-22 78.2 0.0 1.1e-21 77.4 0.0 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 KFM22676.1 - 4e-12 46.7 0.0 2.5e-11 44.2 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KFM22676.1 - 1e-07 31.6 0.0 1.9e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFM22676.1 - 2.8e-06 27.3 0.1 6.2e-06 26.1 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFM22676.1 - 0.01 16.0 0.0 0.017 15.3 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain FHA PF00498.26 KFM22678.1 - 8.8e-13 48.4 0.0 1.4e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 FHA domain zf-C3HC4_3 PF13920.6 KFM22678.1 - 3.3e-06 26.8 3.0 4.7e-06 26.4 1.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM22678.1 - 4.3e-06 26.5 0.9 4.3e-06 26.5 0.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFM22678.1 - 4.8e-06 26.3 2.1 1.4e-05 24.9 2.1 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KFM22678.1 - 1.8e-05 24.6 3.3 2.3e-05 24.2 1.1 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 KFM22678.1 - 2.3e-05 24.6 1.6 7.7e-05 22.9 1.6 1.9 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KFM22678.1 - 6.3e-05 22.9 0.6 0.00018 21.4 0.6 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFM22678.1 - 0.00052 19.8 2.5 0.00052 19.8 2.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Yop-YscD_cpl PF16697.5 KFM22678.1 - 0.0043 17.3 0.0 0.033 14.5 0.0 2.2 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4_4 PF15227.6 KFM22678.1 - 0.0081 16.3 1.5 0.019 15.1 1.5 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KFM22678.1 - 0.069 13.5 0.6 0.2 11.9 0.6 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_6 PF14835.6 KFM22678.1 - 0.3 11.0 2.4 0.34 10.8 0.8 1.8 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 KFM22678.1 - 0.36 10.7 1.8 0.73 9.7 1.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Aminotran_1_2 PF00155.21 KFM22680.1 - 4.8e-46 157.6 0.0 5.7e-46 157.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KFM22680.1 - 0.0006 18.9 0.0 0.00086 18.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KFM22680.1 - 0.0028 17.0 0.0 0.0059 15.9 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 KFM22680.1 - 0.0034 16.0 0.0 0.0048 15.5 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF707 PF05212.12 KFM22681.1 - 1.7e-07 30.8 0.2 8e-06 25.3 0.2 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF707) Aminotran_3 PF00202.21 KFM22682.1 - 1.2e-37 129.6 0.0 7.8e-29 100.5 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.6 KFM22682.1 - 2.6e-13 50.2 0.0 4.2e-08 33.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain DUF707 PF05212.12 KFM22682.1 - 8.5e-05 22.0 0.0 0.00019 20.8 0.0 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF707) AAA_25 PF13481.6 KFM22682.1 - 0.0033 17.0 2.7 0.0039 16.8 0.1 2.2 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 KFM22682.1 - 0.083 12.9 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain CX9C PF16860.5 KFM22683.1 - 0.016 15.2 0.7 0.023 14.7 0.1 1.6 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, zf-RING-like PF08746.11 KFM22683.1 - 0.028 14.7 0.2 0.064 13.6 0.2 1.7 1 0 0 1 1 1 0 RING-like domain DnaJ PF00226.31 KFM22684.1 - 2.6e-13 49.9 0.0 3.3e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.13 KFM22684.1 - 1.1e-12 47.5 0.2 1.5e-12 47.1 0.2 1.2 1 0 0 1 1 1 1 CSL zinc finger AAA PF00004.29 KFM22685.1 - 6e-44 149.7 0.3 4.3e-42 143.7 0.0 3.5 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Peptidase_M41 PF01434.18 KFM22685.1 - 1.6e-23 83.5 0.1 3.3e-23 82.5 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA_lid_3 PF17862.1 KFM22685.1 - 2.4e-07 30.5 0.2 1.1e-06 28.4 0.2 2.2 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KFM22685.1 - 3.8e-05 24.1 0.7 3.8e-05 24.1 0.7 3.1 1 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 KFM22685.1 - 6.6e-05 22.7 0.0 0.00022 21.0 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein RuvB_N PF05496.12 KFM22685.1 - 0.00015 21.6 0.0 0.0024 17.6 0.0 2.7 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KFM22685.1 - 0.00023 21.5 3.3 0.013 15.8 0.0 3.7 3 1 0 4 4 4 1 AAA domain AAA_33 PF13671.6 KFM22685.1 - 0.0003 21.0 0.0 0.0011 19.1 0.0 2.1 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 KFM22685.1 - 0.0018 17.5 0.1 0.0033 16.7 0.1 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 KFM22685.1 - 0.0022 18.0 0.3 0.016 15.2 0.3 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KFM22685.1 - 0.0084 16.2 0.2 0.072 13.2 0.0 2.7 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 KFM22685.1 - 0.011 16.3 0.5 0.047 14.3 0.0 2.5 3 0 0 3 3 1 0 AAA domain Mg_chelatase PF01078.21 KFM22685.1 - 0.022 14.1 0.0 0.054 12.9 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI CPT PF07931.12 KFM22685.1 - 0.041 13.7 0.0 0.98 9.2 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Sigma54_activat PF00158.26 KFM22685.1 - 0.061 13.0 0.0 0.31 10.7 0.0 2.1 1 1 1 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 KFM22685.1 - 0.11 12.0 1.5 2.8 7.5 0.1 3.0 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 KFM22685.1 - 0.15 12.4 0.0 0.91 9.9 0.0 2.3 2 0 0 2 2 2 0 RNA helicase TmoB PF06234.12 KFM22685.1 - 0.59 10.3 2.9 8.6 6.5 0.0 3.0 3 0 0 3 3 3 0 Toluene-4-monooxygenase system protein B (TmoB) Tombus_movement PF05318.12 KFM22685.1 - 1.4 9.8 4.4 5.8 7.8 4.4 2.1 1 0 0 1 1 1 0 Tombusvirus movement protein FKBP_C PF00254.28 KFM22687.1 - 9.5e-20 70.7 0.0 1.8e-19 69.8 0.0 1.4 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase HATPase_c PF02518.26 KFM22688.1 - 3.3e-24 85.6 0.0 7.7e-24 84.4 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Bac_rhodopsin PF01036.18 KFM22688.1 - 1.6e-18 67.1 15.2 2.5e-18 66.5 15.2 1.3 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Response_reg PF00072.24 KFM22688.1 - 1.1e-16 61.0 0.0 1.9e-13 50.5 0.0 2.9 2 1 1 3 3 3 2 Response regulator receiver domain HisKA PF00512.25 KFM22688.1 - 1e-11 44.7 0.2 2.8e-11 43.3 0.2 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 KFM22688.1 - 0.069 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LEA_2 PF03168.13 KFM22688.1 - 0.17 12.5 0.0 0.4 11.2 0.0 1.6 1 0 0 1 1 1 0 Late embryogenesis abundant protein zf-CCHC_3 PF13917.6 KFM22690.1 - 0.003 17.5 0.1 0.003 17.5 0.1 1.7 2 0 0 2 2 2 1 Zinc knuckle AP3D1 PF06375.11 KFM22690.1 - 0.089 13.0 9.6 0.12 12.6 9.6 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 zf-CCHC PF00098.23 KFM22690.1 - 0.15 12.2 2.5 0.25 11.5 2.5 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 KFM22690.1 - 0.23 11.2 2.5 0.39 10.5 2.5 1.4 1 0 0 1 1 1 0 Zinc knuckle Med19 PF10278.9 KFM22690.1 - 0.31 11.0 10.8 1.1 9.2 10.8 1.8 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 zf-CCHC_2 PF13696.6 KFM22690.1 - 1.2 9.1 3.2 1.7 8.6 3.2 1.2 1 0 0 1 1 1 0 Zinc knuckle Aldose_epim PF01263.20 KFM22691.1 - 6.4e-96 321.2 0.0 7.6e-96 321.0 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase YqaJ PF09588.10 KFM22693.1 - 1e-20 74.4 0.0 1.4e-20 73.9 0.0 1.2 1 0 0 1 1 1 1 YqaJ-like viral recombinase domain SQS_PSY PF00494.19 KFM22694.1 - 1.6e-44 152.4 0.0 1.6e-44 152.4 0.0 2.1 2 0 0 2 2 2 1 Squalene/phytoene synthase Methyltr_RsmB-F PF01189.17 KFM22695.1 - 1.4e-14 54.2 0.0 2.2e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F PUA PF01472.20 KFM22695.1 - 8.5e-07 28.8 1.6 4.6e-06 26.5 1.6 2.1 1 1 0 1 1 1 1 PUA domain CPP1-like PF11833.8 KFM22696.1 - 1.6e-18 67.1 0.0 2.1e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF2613 PF11021.8 KFM22696.1 - 0.21 11.7 8.0 0.14 12.3 6.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2613) Torus PF16131.5 KFM22697.1 - 4e-05 24.3 0.2 9.6e-05 23.0 0.2 1.6 1 0 0 1 1 1 1 Torus domain zf-CCCH_4 PF18044.1 KFM22697.1 - 6.9e-05 22.5 8.1 0.00014 21.5 8.1 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KFM22697.1 - 0.003 17.6 8.7 0.003 17.6 8.7 1.6 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH PF00642.24 KFM22697.1 - 0.0055 16.6 5.0 0.0099 15.8 5.0 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 KFM22697.1 - 0.11 13.0 2.9 0.19 12.2 2.9 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger FAM76 PF16046.5 KFM22697.1 - 0.64 9.3 2.2 0.89 8.8 2.2 1.1 1 0 0 1 1 1 0 FAM76 protein Ank PF00023.30 KFM22698.1 - 0.0011 19.3 0.6 0.0034 17.8 0.6 1.9 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 KFM22698.1 - 0.011 16.2 0.1 0.038 14.5 0.1 2.0 1 0 0 1 1 1 0 Ankyrin repeat Copper-bind PF00127.20 KFM22699.1 - 5.9e-14 52.3 0.2 3.1e-07 30.8 0.0 2.5 2 1 0 2 2 2 2 Copper binding proteins, plastocyanin/azurin family Cu_bind_like PF02298.17 KFM22699.1 - 2.2e-06 27.6 0.0 0.029 14.4 0.0 2.2 2 0 0 2 2 2 2 Plastocyanin-like domain SoxE PF06525.11 KFM22699.1 - 5e-05 22.8 0.2 0.011 15.2 0.1 2.2 1 1 1 2 2 2 2 Sulfocyanin (SoxE) domain Hva1_TUDOR PF11160.8 KFM22699.1 - 0.0085 16.2 0.5 3.7 7.8 0.1 2.5 2 0 0 2 2 2 2 Hypervirulence associated proteins TUDOR domain DUF3715 PF12509.8 KFM22699.1 - 0.072 13.1 0.0 3.5 7.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3715) Cu-oxidase_2 PF07731.14 KFM22699.1 - 0.075 12.8 0.0 1.3 8.8 0.0 2.4 2 0 0 2 2 2 0 Multicopper oxidase PKD PF00801.20 KFM22699.1 - 2.4 8.1 11.5 11 5.9 3.1 3.4 2 2 0 2 2 2 0 PKD domain Ribosomal_S16 PF00886.19 KFM22700.1 - 1.1e-25 89.5 0.0 1.5e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 Voltage_CLC PF00654.20 KFM22701.1 - 1.7e-59 201.9 35.0 1.5e-56 192.2 31.5 3.0 1 1 1 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 KFM22701.1 - 0.027 14.9 0.1 0.049 14.1 0.1 1.4 1 0 0 1 1 1 0 CBS domain Formyl_trans_N PF00551.19 KFM22702.1 - 3.4e-49 167.0 0.0 4.4e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase DUF1995 PF09353.10 KFM22703.1 - 2.8e-32 112.4 0.0 3.5e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) DUF4281 PF14108.6 KFM22704.1 - 3.5e-09 37.1 0.8 6.1e-09 36.3 0.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4281) DUF485 PF04341.12 KFM22704.1 - 0.087 12.8 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF485 ParA PF10609.9 KFM22705.1 - 6.4e-76 255.0 0.0 9.1e-76 254.6 0.0 1.2 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase FeS_assembly_P PF01883.19 KFM22705.1 - 9.5e-17 60.9 0.1 9.5e-17 60.9 0.1 2.9 3 0 0 3 3 3 1 Iron-sulfur cluster assembly protein CbiA PF01656.23 KFM22705.1 - 2.3e-11 43.8 0.0 4.3e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KFM22705.1 - 1.9e-10 41.0 0.1 6.8e-09 35.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 KFM22705.1 - 1.6e-07 30.9 0.0 3e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 ATPase MipZ VirC1 PF07015.11 KFM22705.1 - 0.00043 19.6 0.1 0.00078 18.8 0.1 1.4 1 0 0 1 1 1 1 VirC1 protein Fer4_NifH PF00142.18 KFM22705.1 - 0.00087 18.8 0.2 0.0038 16.7 0.1 1.9 1 1 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 KFM22705.1 - 0.016 14.4 0.2 0.036 13.2 0.2 1.6 1 0 0 1 1 1 0 Anion-transporting ATPase Not3 PF04065.15 KFM22705.1 - 0.25 10.8 1.0 0.38 10.1 1.0 1.1 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component ZapB PF06005.12 KFM22705.1 - 3.3 8.2 10.4 0.64 10.5 3.0 2.3 2 0 0 2 2 2 0 Cell division protein ZapB Spc7 PF08317.11 KFM22705.1 - 4.1 6.2 7.5 7 5.4 7.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 KFM22705.1 - 4.5 6.5 9.4 12 5.1 8.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Clathrin PF00637.20 KFM22706.1 - 2.2e-11 43.8 0.0 9.2e-11 41.8 0.0 1.9 2 0 0 2 2 2 1 Region in Clathrin and VPS ANAPC4_WD40 PF12894.7 KFM22706.1 - 2.2e-05 24.7 0.0 5.9e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFM22706.1 - 0.0023 18.7 0.0 0.0069 17.2 0.0 1.9 1 0 0 1 1 1 1 WD domain, G-beta repeat DEAD PF00270.29 KFM22707.1 - 1.3e-10 41.4 0.1 1.9e-10 40.8 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase UVR PF02151.19 KFM22707.1 - 2.7e-06 26.9 0.1 4.7e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 UvrB/uvrC motif Helicase_C PF00271.31 KFM22708.1 - 1.1e-10 41.8 0.0 1.8e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFM22708.1 - 9.9e-07 28.7 0.0 0.0038 17.0 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Ssl1 PF04056.14 KFM22709.1 - 3.4e-63 212.9 0.0 4.6e-63 212.5 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 KFM22709.1 - 9.5e-11 41.8 17.8 1.3e-09 38.2 18.4 2.6 1 1 1 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 KFM22709.1 - 2.2e-09 37.9 0.0 1.2e-08 35.5 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain DUF3898 PF13037.6 KFM22709.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3898) zf-4CXXC_R1 PF10497.9 KFM22709.1 - 2.8 8.2 12.9 5.8 7.2 12.9 1.5 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 IBR PF01485.21 KFM22709.1 - 4.8 7.5 18.6 58 4.0 18.6 2.5 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Utp11 PF03998.13 KFM22710.1 - 1.6e-73 247.6 8.3 1.9e-73 247.4 8.3 1.0 1 0 0 1 1 1 1 Utp11 protein EutB PF06751.11 KFM22710.1 - 0.1 11.4 0.1 0.18 10.6 0.1 1.3 1 0 0 1 1 1 0 Ethanolamine ammonia lyase large subunit (EutB) SLATT_5 PF18160.1 KFM22710.1 - 0.12 11.7 0.1 0.21 10.9 0.1 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 RMMBL PF07521.12 KFM22710.1 - 0.16 12.0 0.1 0.59 10.1 0.0 2.0 2 0 0 2 2 2 0 Zn-dependent metallo-hydrolase RNA specificity domain ATP-synt PF00231.19 KFM22711.1 - 7.1e-77 258.9 4.5 8.3e-77 258.6 4.5 1.0 1 0 0 1 1 1 1 ATP synthase PCRF PF03462.18 KFM22712.1 - 7.9e-65 218.3 1.8 1.7e-64 217.3 1.8 1.5 1 0 0 1 1 1 1 PCRF domain RF-1 PF00472.20 KFM22712.1 - 8.7e-37 125.6 1.0 8.7e-37 125.6 1.0 1.7 2 0 0 2 2 2 1 RF-1 domain ABC_tran_CTD PF16326.5 KFM22712.1 - 0.023 14.9 1.1 0.023 14.9 1.1 3.3 4 1 1 5 5 5 0 ABC transporter C-terminal domain DUF4407 PF14362.6 KFM22712.1 - 1.9 7.8 11.1 0.18 11.1 2.9 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) NAD_Gly3P_dh_C PF07479.14 KFM22714.1 - 1e-44 152.2 0.3 1.5e-44 151.7 0.3 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 KFM22714.1 - 9.1e-40 136.2 0.0 1.4e-39 135.5 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 KFM22714.1 - 2.2e-06 27.4 0.0 5e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 KFM22714.1 - 0.00065 20.2 0.0 0.0025 18.4 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Abhydrolase_1 PF00561.20 KFM22714.1 - 0.009 15.7 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold CS PF04969.16 KFM22715.1 - 4e-08 34.2 0.0 1.8e-07 32.0 0.0 1.9 1 1 0 1 1 1 1 CS domain Pept_tRNA_hydro PF01195.19 KFM22717.1 - 4.6e-27 95.1 0.0 9.2e-27 94.1 0.0 1.4 1 1 0 1 1 1 1 Peptidyl-tRNA hydrolase RRM_1 PF00076.22 KFM22717.1 - 2.2e-18 65.9 0.0 3.4e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer PF06495.11 KFM22717.1 - 0.0031 17.6 22.5 0.0055 16.8 22.5 1.4 1 0 0 1 1 1 1 Fruit fly transformer protein RRM_5 PF13893.6 KFM22717.1 - 0.05 13.2 0.0 0.69 9.5 0.0 2.5 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 KFM22719.1 - 6.3e-57 192.9 0.0 1.2e-56 192.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 KFM22719.1 - 1.8e-34 117.7 1.0 1e-16 60.7 0.1 2.8 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 KFM22719.1 - 8.1e-24 84.3 0.0 1.9e-23 83.1 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM22719.1 - 0.00046 19.6 0.0 0.0048 16.2 0.0 2.2 2 0 0 2 2 2 1 Kinase-like WD40 PF00400.32 KFM22720.1 - 1.5e-52 174.4 24.4 4.4e-06 27.3 0.2 11.7 11 1 0 11 11 11 9 WD domain, G-beta repeat Utp13 PF08625.11 KFM22720.1 - 2e-34 118.5 0.0 3.2e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 KFM22720.1 - 4.2e-16 59.0 2.0 0.041 14.2 0.0 8.2 3 2 6 9 9 9 6 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFM22720.1 - 1.9e-05 23.5 6.2 1.3 7.6 0.0 5.9 4 2 1 6 6 6 3 Nucleoporin Nup120/160 Ammonium_transp PF00909.21 KFM22720.1 - 0.014 14.1 0.2 0.023 13.4 0.2 1.3 1 0 0 1 1 1 0 Ammonium Transporter Family Nucleoporin_N PF08801.11 KFM22720.1 - 0.025 13.3 0.0 21 3.7 0.0 4.0 3 1 1 5 5 5 0 Nup133 N terminal like Ge1_WD40 PF16529.5 KFM22720.1 - 2.7 6.8 7.2 89 1.9 0.2 4.9 3 2 3 6 6 6 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CPL PF08144.11 KFM22722.1 - 1.2e-10 41.9 0.0 1.6e-06 28.5 0.0 3.8 3 1 0 3 3 3 2 CPL (NUC119) domain PUF PF00806.19 KFM22722.1 - 4.9e-07 29.1 0.0 0.071 12.8 0.0 3.7 3 0 0 3 3 3 2 Pumilio-family RNA binding repeat Mob1_phocein PF03637.17 KFM22723.1 - 1.9e-61 207.0 0.0 3.5e-61 206.1 0.0 1.4 1 1 0 1 1 1 1 Mob1/phocein family RRM_1 PF00076.22 KFM22723.1 - 2.4e-20 72.1 0.0 6.3e-20 70.8 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.8 KFM22723.1 - 2.2e-13 50.7 0.4 7.5e-13 48.9 0.4 2.0 1 1 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal PAPS_reduct PF01507.19 KFM22724.1 - 5.4e-40 137.3 0.0 9.4e-40 136.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Thioredoxin PF00085.20 KFM22724.1 - 3.9e-14 52.5 0.0 6.5e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KFM22724.1 - 1.1e-06 29.1 0.1 1.5e-05 25.4 0.1 2.5 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 KFM22724.1 - 1.9e-05 24.6 0.0 3.6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family TraF PF13728.6 KFM22724.1 - 5.6e-05 23.1 0.3 0.00014 21.8 0.0 1.7 2 1 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 KFM22724.1 - 0.00042 20.4 0.0 0.0012 19.0 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 KFM22724.1 - 0.0045 16.7 0.0 0.0095 15.7 0.0 1.5 1 0 0 1 1 1 1 Redoxin OST3_OST6 PF04756.13 KFM22724.1 - 0.17 11.2 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 KFM22724.1 - 0.2 12.0 0.0 1.4 9.3 0.0 2.2 2 1 1 3 3 3 0 Thioredoxin-like Lar_restr_allev PF14354.6 KFM22724.1 - 3.1 8.2 5.1 4.3 7.8 1.4 2.4 2 0 0 2 2 2 0 Restriction alleviation protein Lar Trypsin_2 PF13365.6 KFM22725.1 - 1.4e-34 120.2 1.2 2.4e-34 119.4 1.2 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 KFM22725.1 - 1.8e-15 57.4 0.1 5.6e-15 55.8 0.1 1.6 1 1 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 KFM22725.1 - 2.5e-11 43.8 0.0 5.1e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFM22725.1 - 0.00043 20.6 0.8 0.016 15.5 0.3 2.9 2 1 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 KFM22725.1 - 0.002 17.9 6.5 0.034 14.0 0.3 2.8 3 0 0 3 3 3 2 PDZ domain Peptidase_S46 PF10459.9 KFM22725.1 - 0.0084 14.8 0.5 0.027 13.2 0.6 1.6 2 0 0 2 2 2 1 Peptidase S46 Peptidase_S32 PF05579.13 KFM22725.1 - 0.025 13.8 0.2 4.1 6.5 0.1 2.1 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 Peptidase_S3 PF00944.19 KFM22725.1 - 0.18 11.6 0.2 0.43 10.4 0.2 1.6 1 0 0 1 1 1 0 Alphavirus core protein DUF4743 PF15916.5 KFM22726.1 - 3e-26 91.8 0.0 4.4e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 KFM22726.1 - 9.8e-06 25.6 0.1 1.4e-05 25.2 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain ESX-1_EspG PF14011.6 KFM22726.1 - 0.0055 16.4 0.1 0.011 15.4 0.1 1.4 1 0 0 1 1 1 1 EspG family DnaJ PF00226.31 KFM22728.1 - 5.9e-20 71.2 0.5 9.4e-20 70.5 0.2 1.5 2 0 0 2 2 2 1 DnaJ domain Gp-FAR-1 PF05823.12 KFM22728.1 - 0.057 13.8 0.0 0.081 13.3 0.0 1.1 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) CS PF04969.16 KFM22729.1 - 0.0047 17.9 0.0 0.0081 17.2 0.0 1.3 1 0 0 1 1 1 1 CS domain tRNA-synt_2_TM PF16995.5 KFM22731.1 - 0.091 12.4 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Transmembrane region of lysyl-tRNA synthetase Spt5-NGN PF03439.13 KFM22733.1 - 9.3e-19 67.1 0.1 1e-08 35.0 0.0 2.6 2 0 0 2 2 2 2 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 KFM22733.1 - 5.2e-14 53.0 6.8 5.2e-14 53.0 6.8 3.0 2 1 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.29 KFM22733.1 - 3.5e-10 39.5 27.9 0.063 13.2 3.3 6.6 6 0 0 6 6 6 5 KOW motif Acetyltransf_1 PF00583.25 KFM22734.1 - 1e-14 54.7 0.1 1.3e-14 54.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFM22734.1 - 2.9e-09 36.9 0.1 3.9e-09 36.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFM22734.1 - 5.1e-08 33.2 0.1 8.1e-08 32.6 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFM22734.1 - 7.1e-05 22.7 0.1 0.00012 22.0 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KFM22734.1 - 0.0019 18.3 0.4 0.0029 17.7 0.4 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KFM22734.1 - 0.14 12.3 0.1 0.2 11.8 0.1 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Bot1p PF12298.8 KFM22736.1 - 6.4e-05 23.2 0.4 0.0014 18.9 0.0 2.7 3 0 0 3 3 3 1 Eukaryotic mitochondrial regulator protein MRP-L20 PF12824.7 KFM22736.1 - 0.0008 19.6 0.0 0.0014 18.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 SET PF00856.28 KFM22737.1 - 3.4e-05 24.3 0.0 4.9e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 SET domain CwfJ_C_1 PF04677.15 KFM22738.1 - 2e-23 82.6 0.0 3.1e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 RRM_1 PF00076.22 KFM22738.1 - 1.9e-14 53.2 0.0 3.6e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CwfJ_C_2 PF04676.14 KFM22738.1 - 1e-08 35.9 0.0 2.3e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Mob_synth_C PF06463.13 KFM22739.1 - 6.7e-36 123.0 0.0 1.5e-35 122.0 0.0 1.6 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 KFM22739.1 - 1.8e-33 116.3 0.0 2.7e-33 115.7 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KFM22739.1 - 2.3e-05 24.7 0.0 4.3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KFM22739.1 - 0.011 15.8 0.0 0.034 14.3 0.0 1.7 2 0 0 2 2 2 0 4Fe-4S single cluster domain CMD PF02627.20 KFM22739.1 - 0.045 13.8 0.5 0.51 10.4 0.2 2.6 2 0 0 2 2 2 0 Carboxymuconolactone decarboxylase family GLTT PF01744.20 KFM22739.1 - 0.051 13.3 1.0 0.11 12.2 1.0 1.5 1 0 0 1 1 1 0 GLTT repeat (6 copies) Pkinase PF00069.25 KFM22740.1 - 4.1e-61 206.6 0.0 5.1e-61 206.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM22740.1 - 1.1e-30 106.8 0.0 1.5e-30 106.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFM22740.1 - 6e-06 26.3 0.1 2.5e-05 24.3 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KFM22740.1 - 0.00018 20.9 0.0 0.0013 18.1 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Choline_kinase PF01633.20 KFM22740.1 - 0.0027 17.3 0.0 0.0041 16.7 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 KFM22740.1 - 0.0076 15.6 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFM22740.1 - 0.1 11.5 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KFM22740.1 - 0.13 11.0 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 KFM22740.1 - 0.2 11.2 0.0 1.2 8.7 0.0 1.8 1 1 1 2 2 2 0 RIO1 family Rhomboid PF01694.22 KFM22741.1 - 6.7e-23 81.3 17.0 6.7e-23 81.3 17.0 1.6 2 0 0 2 2 2 1 Rhomboid family DER1 PF04511.15 KFM22741.1 - 3.2e-07 30.5 0.8 1.3e-06 28.5 0.8 1.8 1 1 0 1 1 1 1 Der1-like family DUF1751 PF08551.10 KFM22741.1 - 0.0011 19.4 3.8 0.002 18.7 1.4 2.5 3 1 0 3 3 3 1 Eukaryotic integral membrane protein (DUF1751) DUF150 PF02576.17 KFM22742.1 - 0.00098 19.5 0.0 0.0019 18.6 0.0 1.5 1 0 0 1 1 1 1 RimP N-terminal domain RAMA PF18755.1 KFM22743.1 - 3e-23 82.3 0.1 5.3e-23 81.5 0.1 1.4 1 0 0 1 1 1 1 Restriction Enzyme Adenine Methylase Associated ELMO_CED12 PF04727.13 KFM22744.1 - 3.7e-18 66.3 0.0 5.1e-16 59.3 0.0 2.0 1 1 0 1 1 1 1 ELMO/CED-12 family GpcrRhopsn4 PF10192.9 KFM22745.1 - 0.0053 16.2 0.7 0.0053 16.2 0.7 1.9 2 0 0 2 2 2 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.13 KFM22745.1 - 0.011 15.0 0.2 0.011 15.0 0.2 2.2 3 0 0 3 3 3 0 Lung seven transmembrane receptor WD40 PF00400.32 KFM22746.1 - 9.5e-11 42.1 8.5 8.7e-07 29.6 0.2 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.8 KFM22746.1 - 0.15 10.7 0.0 0.23 10.1 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Raffinose_syn PF05691.12 KFM22747.1 - 1e-08 33.5 0.0 1.1e-08 33.4 0.0 1.0 1 0 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 MAD PF05557.13 KFM22749.1 - 2e-34 119.0 2.3 2e-34 119.0 2.3 2.2 1 1 1 2 2 2 1 Mitotic checkpoint protein KASH_CCD PF14662.6 KFM22749.1 - 0.001 18.9 20.4 0.48 10.2 1.7 4.2 3 2 1 4 4 4 2 Coiled-coil region of CCDC155 or KASH BLOC1_2 PF10046.9 KFM22749.1 - 0.029 14.7 4.3 1.1 9.6 0.4 3.6 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fzo_mitofusin PF04799.13 KFM22749.1 - 0.84 9.2 5.0 0.62 9.6 0.6 2.9 3 0 0 3 3 3 0 fzo-like conserved region JIP_LZII PF16471.5 KFM22749.1 - 2.8 8.2 7.0 6.4 7.0 0.4 4.0 3 1 1 4 4 4 0 JNK-interacting protein leucine zipper II Raffinose_syn PF05691.12 KFM22750.1 - 1.3e-136 456.4 0.0 1.8e-108 363.3 0.0 2.0 2 0 0 2 2 2 2 Raffinose synthase or seed imbibition protein Sip1 GBP PF02263.19 KFM22751.1 - 8.5e-55 185.8 0.0 1.2e-47 162.3 0.0 2.1 1 1 1 2 2 2 2 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 KFM22751.1 - 4.2e-08 32.9 0.3 4.2e-08 32.9 0.3 2.1 1 1 0 2 2 2 1 Guanylate-binding protein, C-terminal domain Aa_trans PF01490.18 KFM22752.1 - 6.4e-94 315.0 26.2 1.9e-55 188.2 7.3 3.1 2 1 1 3 3 3 3 Transmembrane amino acid transporter protein Aa_trans PF01490.18 KFM22753.1 - 1.2e-64 218.6 11.4 2.3e-43 148.4 17.8 2.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KFM22753.1 - 1e-07 31.4 12.2 1e-07 31.4 12.2 1.8 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family WD40 PF00400.32 KFM22756.1 - 1.2e-31 108.3 17.6 1.3e-06 29.0 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM22756.1 - 3.1e-15 56.2 0.2 0.37 11.1 0.1 5.9 2 1 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFM22756.1 - 0.0014 18.6 0.0 0.72 9.7 0.0 3.0 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFM22756.1 - 0.28 10.1 0.4 5.2 5.9 0.1 2.7 1 1 2 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein SNF2_N PF00176.23 KFM22757.1 - 1.5e-68 231.1 0.0 1.3e-66 224.7 0.0 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain FAD_binding_2 PF00890.24 KFM22757.1 - 5.6e-33 114.6 19.1 1.3e-17 64.0 0.6 2.7 2 1 1 3 3 3 2 FAD binding domain DAO PF01266.24 KFM22757.1 - 2.5e-05 24.1 1.8 2.5e-05 24.1 1.8 2.7 3 1 1 4 4 4 1 FAD dependent oxidoreductase zf-C3HC4 PF00097.25 KFM22757.1 - 2.9e-05 23.8 4.5 7.7e-05 22.5 4.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFM22757.1 - 0.00011 22.0 4.5 0.00011 22.0 4.5 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM22757.1 - 0.00013 22.2 5.8 0.00013 22.2 5.8 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KFM22757.1 - 0.0038 17.2 4.1 0.0084 16.1 4.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KFM22757.1 - 0.0061 16.7 5.1 0.013 15.7 5.1 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KFM22757.1 - 0.012 15.5 7.2 0.026 14.3 6.2 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Auto_anti-p27 PF06677.12 KFM22757.1 - 0.71 10.1 5.0 0.29 11.3 0.8 2.5 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DZR PF12773.7 KFM22757.1 - 0.87 9.7 12.4 1.6 8.8 4.7 2.8 2 0 0 2 2 2 0 Double zinc ribbon zf-RING_5 PF14634.6 KFM22757.1 - 1.2 9.1 14.4 0.03 14.3 4.5 2.6 2 0 0 2 2 2 0 zinc-RING finger domain AAA_2 PF07724.14 KFM22758.1 - 7.2e-34 117.4 0.0 6.3e-30 104.5 0.0 3.8 2 1 1 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KFM22758.1 - 1.9e-33 114.5 1.0 1.9e-33 114.5 1.0 2.5 1 1 1 2 2 2 1 AAA lid domain AAA PF00004.29 KFM22758.1 - 5.3e-21 75.4 0.0 1.2e-13 51.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KFM22758.1 - 3.8e-20 71.7 0.0 3.9e-19 68.5 0.0 2.8 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.20 KFM22758.1 - 5.7e-12 45.6 3.1 1.9e-07 31.1 0.3 3.0 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA_5 PF07728.14 KFM22758.1 - 1.3e-10 41.4 3.5 9.8e-06 25.6 0.0 3.8 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFM22758.1 - 5.1e-07 30.2 7.7 1.9e-05 25.1 0.1 4.4 2 2 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KFM22758.1 - 4.6e-06 26.9 3.4 0.027 14.7 0.0 4.4 3 1 0 3 3 3 2 AAA domain TniB PF05621.11 KFM22758.1 - 0.0013 18.2 2.3 0.028 13.8 0.1 2.8 2 1 0 2 2 2 1 Bacterial TniB protein IstB_IS21 PF01695.17 KFM22758.1 - 0.0075 16.0 1.4 0.041 13.6 0.0 2.7 3 0 0 3 3 2 1 IstB-like ATP binding protein Sigma54_activat PF00158.26 KFM22758.1 - 0.0091 15.7 0.0 3.2 7.4 0.0 3.0 3 1 0 3 3 2 1 Sigma-54 interaction domain AAA_25 PF13481.6 KFM22758.1 - 0.011 15.3 1.1 0.038 13.5 0.1 2.5 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KFM22758.1 - 0.016 15.1 0.6 8.9 6.1 0.0 3.1 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea DUF815 PF05673.13 KFM22758.1 - 0.026 13.7 0.0 0.072 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.12 KFM22758.1 - 0.037 13.9 0.0 0.14 12.1 0.0 2.0 1 1 0 1 1 1 0 NACHT domain AAA_3 PF07726.11 KFM22758.1 - 0.096 12.5 0.0 25 4.7 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KFM22758.1 - 0.15 12.4 1.1 1.9 8.8 0.4 3.0 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KFM22758.1 - 0.21 11.8 4.6 0.99 9.6 0.0 3.4 2 1 1 3 3 3 0 AAA domain DUF4426 PF14467.6 KFM22758.1 - 0.23 11.4 1.0 4.7 7.2 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4426) AAA_23 PF13476.6 KFM22758.1 - 0.7 10.4 6.2 6.8 7.1 4.6 2.4 2 0 0 2 2 2 0 AAA domain GrpE PF01025.19 KFM22758.1 - 1.6 8.4 7.8 4.1 7.0 7.8 1.7 1 0 0 1 1 1 0 GrpE Spc7 PF08317.11 KFM22758.1 - 3.9 6.3 10.1 7.1 5.4 10.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Helicase_C PF00271.31 KFM22761.1 - 1.4e-07 31.8 0.0 2.4e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RRM_2 PF04059.12 KFM22762.1 - 2.8e-44 149.2 0.0 4.5e-44 148.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 KFM22762.1 - 1.4e-06 28.0 0.0 0.007 16.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) F-box-like PF12937.7 KFM22763.1 - 5.7e-07 29.3 1.5 1e-06 28.5 1.5 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFM22763.1 - 0.00039 20.2 0.8 0.0005 19.9 0.8 1.2 1 0 0 1 1 1 1 F-box domain MatE PF01554.18 KFM22764.1 - 4.4e-21 75.2 26.1 9.5e-12 44.9 8.6 3.0 2 2 0 2 2 2 2 MatE Gcd10p PF04189.13 KFM22765.1 - 8.8e-48 162.9 0.0 1.1e-47 162.6 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family Ribosomal_S13 PF00416.22 KFM22766.1 - 6.6e-28 97.7 2.9 1.1e-26 93.8 2.9 2.2 1 1 0 1 1 1 1 Ribosomal protein S13/S18 UCH PF00443.29 KFM22769.1 - 1.4e-11 44.4 0.0 1.6e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFM22769.1 - 0.00053 19.7 0.1 0.00069 19.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 KFM22770.1 - 0.035 13.6 0.0 0.035 13.6 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase DUF1269 PF06897.12 KFM22770.1 - 0.23 11.8 2.3 0.28 11.5 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1269) zf-RING_2 PF13639.6 KFM22771.1 - 7.9e-09 35.7 5.4 1.2e-08 35.2 5.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFM22771.1 - 5.6e-07 29.4 5.4 8.4e-07 28.9 5.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFM22771.1 - 1e-06 28.5 5.1 1.7e-06 27.8 5.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KFM22771.1 - 1.1e-06 28.3 3.1 3.6e-06 26.7 3.4 1.7 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 KFM22771.1 - 1.3e-06 28.1 5.1 2e-06 27.5 5.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFM22771.1 - 2.5e-06 27.2 6.4 5e-06 26.2 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KFM22771.1 - 3.8e-06 26.9 0.8 5.7e-06 26.3 0.8 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KFM22771.1 - 1e-05 25.5 1.4 1e-05 25.5 1.4 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_5 PF17121.5 KFM22771.1 - 0.00041 20.2 5.0 0.0023 17.8 5.3 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFM22771.1 - 0.00043 20.4 5.4 0.00066 19.8 5.4 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KFM22771.1 - 0.0015 18.3 8.2 0.047 13.5 8.9 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KFM22771.1 - 0.057 13.7 5.9 0.18 12.1 5.9 1.7 1 1 1 2 2 2 0 RING-H2 zinc finger domain Rad50_zn_hook PF04423.14 KFM22771.1 - 0.069 13.0 1.0 6.5 6.7 0.1 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif Fer2 PF00111.27 KFM22771.1 - 0.22 11.5 5.2 0.93 9.5 1.3 2.3 1 1 1 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain zf-RING_11 PF17123.5 KFM22771.1 - 0.26 11.0 0.1 0.26 11.0 0.1 2.3 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_10 PF16685.5 KFM22771.1 - 0.53 10.5 5.9 0.87 9.8 5.9 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 FANCL_C PF11793.8 KFM22771.1 - 0.6 10.3 3.2 1.4 9.2 2.1 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-P11 PF03854.14 KFM22771.1 - 2.9 7.6 12.9 1 9.1 9.8 1.9 2 1 0 2 2 2 0 P-11 zinc finger DNA_pol_B PF00136.21 KFM22772.1 - 8.5e-122 407.1 0.0 3.5e-121 405.1 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KFM22772.1 - 1.2e-19 70.7 0.0 3e-19 69.3 0.0 1.7 1 1 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-DNA_Pol PF08996.10 KFM22772.1 - 1.6e-19 70.4 0.0 2.6e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_alpha_N PF12254.8 KFM22772.1 - 4.6e-17 61.9 1.6 8.3e-17 61.0 1.6 1.4 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal DUF1744 PF08490.12 KFM22772.1 - 0.071 11.7 0.0 0.098 11.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) DNA_pol_B_2 PF03175.13 KFM22772.1 - 0.095 11.5 0.1 0.16 10.8 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral T3SS_needle_E PF08988.10 KFM22772.1 - 3.8 7.7 8.4 0.44 10.7 1.3 3.2 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle Peptidase_M22 PF00814.25 KFM22773.1 - 2.8e-89 299.4 0.0 3.3e-89 299.2 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family DnaJ_C PF01556.18 KFM22775.1 - 9.1e-41 139.4 0.0 1.2e-40 139.0 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KFM22775.1 - 4e-28 97.3 1.5 4e-28 97.3 1.5 1.8 2 0 0 2 2 2 1 DnaJ domain RPT PF13446.6 KFM22775.1 - 0.16 11.9 0.0 0.52 10.3 0.0 1.9 1 1 1 2 2 2 0 A repeated domain in UCH-protein Myb_DNA-binding PF00249.31 KFM22776.1 - 1.8e-16 60.0 0.8 2.4e-12 46.8 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFM22776.1 - 6.3e-06 26.3 2.6 0.0001 22.5 0.1 2.8 2 1 1 3 3 3 1 Myb-like DNA-binding domain SLIDE PF09111.10 KFM22776.1 - 0.016 15.3 0.0 0.045 13.8 0.0 1.9 1 1 0 1 1 1 0 SLIDE TEA PF01285.18 KFM22776.1 - 0.072 13.2 0.9 1.4 9.1 0.1 2.9 2 1 1 3 3 3 0 TEA/ATTS domain Myb_DNA-bind_7 PF15963.5 KFM22776.1 - 0.14 12.0 0.3 2.1 8.3 0.0 2.3 2 0 0 2 2 2 0 Myb DNA-binding like Myticin-prepro PF10690.9 KFM22777.1 - 0.66 10.3 4.9 0.81 10.0 4.9 1.1 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel Mito_carr PF00153.27 KFM22778.1 - 7.6e-35 118.7 8.4 1.1e-16 60.5 0.1 4.7 3 1 1 4 4 4 4 Mitochondrial carrier protein Acetyltransf_1 PF00583.25 KFM22778.1 - 6.3e-08 32.9 0.0 1.4e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family AA_kinase PF00696.28 KFM22778.1 - 7.8e-08 32.2 0.5 4.2e-07 29.8 0.2 2.4 2 1 0 2 2 2 1 Amino acid kinase family Acetyltransf_7 PF13508.7 KFM22778.1 - 1.4e-06 28.6 0.0 2.9e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFM22778.1 - 0.00074 19.5 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ODR4-like PF14778.6 KFM22779.1 - 9.2e-30 103.8 0.0 2.6e-28 99.0 0.0 2.6 1 1 0 1 1 1 1 Olfactory receptor 4-like DUF2172 PF09940.9 KFM22780.1 - 0.14 12.6 0.0 0.24 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2172) AP2 PF00847.20 KFM22781.1 - 3.7e-14 52.7 9.0 6.5e-07 29.5 0.9 2.7 3 0 0 3 3 3 2 AP2 domain KI67R PF08065.12 KFM22781.1 - 0.14 12.7 0.6 0.65 10.6 0.1 2.0 2 0 0 2 2 2 0 KI67R (NUC007) repeat Ge1_WD40 PF16529.5 KFM22782.1 - 2.3e-07 30.1 0.0 3.8e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 KFM22782.1 - 0.0019 19.0 0.2 0.075 13.9 0.1 2.7 2 0 0 2 2 2 1 WD domain, G-beta repeat Clathrin PF00637.20 KFM22783.1 - 3.3e-78 260.5 0.0 2.7e-20 72.7 0.0 4.9 5 0 0 5 5 5 4 Region in Clathrin and VPS Clathrin_H_link PF13838.6 KFM22783.1 - 3e-26 91.1 0.1 1.4e-25 89.0 0.1 2.1 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.20 KFM22783.1 - 4.3e-24 83.6 0.0 9.6e-06 25.7 0.2 6.4 6 0 0 6 6 6 5 Clathrin propeller repeat Clathrin-link PF09268.10 KFM22783.1 - 6.3e-09 35.0 0.1 1.7e-08 33.7 0.1 1.8 1 0 0 1 1 1 1 Clathrin, heavy-chain linker LVIVD PF08309.11 KFM22783.1 - 0.00042 19.6 0.0 0.00098 18.4 0.0 1.5 1 0 0 1 1 1 1 LVIVD repeat TPR_7 PF13176.6 KFM22783.1 - 1.2 9.3 9.7 0.64 10.2 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFM22783.1 - 4.5 7.0 5.5 2.6 7.8 0.1 3.5 3 0 0 3 3 3 0 TPR repeat TPR_14 PF13428.6 KFM22783.1 - 5.1 8.2 26.8 8.9 7.4 1.1 8.2 5 2 3 8 8 8 0 Tetratricopeptide repeat Clathrin PF00637.20 KFM22784.1 - 4.5e-78 260.0 0.1 1.1e-24 86.9 0.0 3.7 4 0 0 4 4 4 3 Region in Clathrin and VPS Vps8 PF12816.7 KFM22784.1 - 1.5e-06 27.9 0.1 0.0015 18.1 0.0 3.3 3 0 0 3 3 3 2 Golgi CORVET complex core vacuolar protein 8 Coatomer_WDAD PF04053.14 KFM22784.1 - 0.0079 15.3 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region STAS PF01740.21 KFM22785.1 - 3.6e-20 71.8 0.0 4.1e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KFM22785.1 - 0.0064 16.8 0.1 0.0092 16.3 0.1 1.3 1 0 0 1 1 1 1 STAS domain Sulfate_transp PF00916.20 KFM22786.1 - 1.4e-134 448.6 32.7 5.8e-66 222.8 12.6 3.1 1 1 2 3 3 3 3 Sulfate permease family STAS PF01740.21 KFM22786.1 - 1.5e-18 66.5 0.0 2.5e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 STAS domain FliP PF00813.20 KFM22786.1 - 0.0074 16.2 6.0 0.35 10.7 0.6 2.4 2 0 0 2 2 2 2 FliP family STAS_2 PF13466.6 KFM22786.1 - 0.11 12.9 0.1 0.25 11.7 0.1 1.5 1 0 0 1 1 1 0 STAS domain DUF4010 PF13194.6 KFM22786.1 - 7 6.3 35.1 0.91 9.2 1.2 5.2 4 1 1 5 5 5 0 Domain of unknown function (DUF4010) DAGK_acc PF00609.19 KFM22787.1 - 1.9e-33 116.0 0.0 2.8e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 KFM22787.1 - 3.5e-20 71.9 0.0 6.3e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Rieske PF00355.26 KFM22787.1 - 4.6e-11 42.5 0.0 1.3e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 KFM22787.1 - 1.4e-09 38.3 0.0 2.9e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.26 KFM22788.1 - 1.6e-12 47.2 0.0 3.8e-12 46.0 0.0 1.5 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain LysM PF01476.20 KFM22788.1 - 0.012 15.7 0.0 1.2 9.3 0.0 2.3 2 0 0 2 2 2 0 LysM domain FAD_syn PF06574.12 KFM22789.1 - 6e-15 55.5 0.0 1.5e-14 54.2 0.0 1.6 1 1 0 1 1 1 1 FAD synthetase CTP_transf_like PF01467.26 KFM22789.1 - 0.046 13.9 0.0 0.099 12.8 0.0 1.7 2 0 0 2 2 2 0 Cytidylyltransferase-like zf-RING_2 PF13639.6 KFM22790.1 - 1.2e-13 51.2 2.5 2.3e-13 50.2 2.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KFM22790.1 - 1e-10 41.2 2.5 1.9e-10 40.3 2.5 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFM22790.1 - 4.2e-09 36.1 2.6 8e-09 35.2 2.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM22790.1 - 1e-08 34.9 1.3 1.7e-08 34.1 1.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 KFM22790.1 - 2e-08 34.1 0.0 3.6e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 PA domain zf-rbx1 PF12678.7 KFM22790.1 - 9.9e-06 25.8 7.6 6.5e-05 23.1 7.6 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KFM22790.1 - 1.4e-05 25.0 2.4 3.3e-05 23.8 2.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFM22790.1 - 0.00031 20.6 1.2 0.0006 19.7 1.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 KFM22790.1 - 0.00035 20.1 3.5 0.00036 20.1 2.1 1.6 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 KFM22790.1 - 0.0028 17.7 2.4 0.006 16.6 2.2 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 KFM22790.1 - 0.0035 17.5 1.2 0.0083 16.3 1.2 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 KFM22790.1 - 0.012 15.5 1.4 0.022 14.6 1.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 KFM22790.1 - 0.1 12.7 1.6 0.33 11.1 1.6 1.9 1 1 0 1 1 1 0 RING-variant domain Prok-RING_4 PF14447.6 KFM22790.1 - 0.28 11.1 1.8 0.5 10.3 1.8 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PUB PF09409.10 KFM22791.1 - 5.6e-11 42.2 0.0 8.1e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 PUB domain SelB-wing_1 PF09105.10 KFM22791.1 - 3.2 7.8 6.4 5.5 7.1 5.6 1.8 1 1 0 1 1 1 0 Elongation factor SelB, winged helix Adaptin_N PF01602.20 KFM22792.1 - 6.8e-93 312.0 0.0 2.3e-73 247.5 0.0 3.0 2 1 0 2 2 2 2 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 KFM22792.1 - 2.1e-05 24.8 0.0 3.7e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain Alpha_adaptin_C PF02296.16 KFM22792.1 - 0.069 13.3 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Alpha adaptin AP2, C-terminal domain Cnd1 PF12717.7 KFM22792.1 - 0.14 12.2 0.0 0.86 9.6 0.0 2.0 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 RRM_1 PF00076.22 KFM22793.1 - 9.1e-37 124.7 0.0 2.2e-13 49.8 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S17 PF00366.20 KFM22793.1 - 1.6e-21 76.1 0.5 2.7e-21 75.4 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 RRM_3 PF08777.11 KFM22793.1 - 3.5e-08 33.4 0.0 0.00021 21.3 0.0 4.0 4 0 0 4 4 4 1 RNA binding motif RRM_occluded PF16842.5 KFM22793.1 - 2.4e-06 27.3 0.0 0.002 17.9 0.0 3.3 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_5 PF13893.6 KFM22793.1 - 4.2e-05 23.1 0.0 0.024 14.2 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KFM22793.1 - 0.00059 19.9 0.1 0.084 13.0 0.0 3.1 3 0 0 3 3 3 1 Limkain b1 Nup35_RRM_2 PF14605.6 KFM22793.1 - 0.0011 18.9 0.9 4.2 7.4 0.0 4.1 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif Syja_N PF02383.18 KFM22795.1 - 9.3e-62 209.2 0.0 1.1e-61 209.0 0.0 1.0 1 0 0 1 1 1 1 SacI homology domain 2OG-FeII_Oxy_3 PF13640.6 KFM22796.1 - 7.7e-15 55.6 0.0 1.3e-14 54.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KFM22796.1 - 9.2e-07 29.3 0.0 2.3e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GATase_5 PF13507.6 KFM22797.1 - 2.2e-79 266.2 0.0 5.6e-42 143.6 0.0 2.3 1 1 1 2 2 2 2 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 KFM22797.1 - 1.1e-33 116.5 8.2 4.3e-19 69.2 0.1 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 KFM22797.1 - 1.6e-19 70.0 0.0 3.2e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 KFM22797.1 - 1.2e-10 41.7 0.0 3.4e-10 40.3 0.0 1.8 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain AIRS PF00586.24 KFM22797.1 - 0.00054 20.6 5.6 0.00072 20.2 0.0 3.5 3 1 0 3 3 3 1 AIR synthase related protein, N-terminal domain OrfB_Zn_ribbon PF07282.11 KFM22797.1 - 0.0071 16.2 5.8 0.0071 16.2 5.8 2.1 2 1 0 2 2 2 1 Putative transposase DNA-binding domain Peptidase_M41 PF01434.18 KFM22799.1 - 5.8e-63 212.2 0.1 1.1e-62 211.3 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KFM22799.1 - 4.7e-46 156.5 0.0 1.1e-45 155.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFM22799.1 - 3.6e-13 49.1 0.2 3.6e-13 49.1 0.2 1.9 2 0 0 2 2 1 1 AAA+ lid domain AAA_5 PF07728.14 KFM22799.1 - 1e-05 25.6 0.1 5.3e-05 23.2 0.0 2.3 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KFM22799.1 - 2.1e-05 23.9 0.0 5.1e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 KFM22799.1 - 0.00019 21.2 0.0 0.0011 18.7 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KFM22799.1 - 0.00027 21.3 0.5 0.009 16.4 0.2 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KFM22799.1 - 0.00065 20.0 0.2 0.093 13.0 0.1 3.4 3 1 0 4 4 3 1 AAA domain AAA_2 PF07724.14 KFM22799.1 - 0.00097 19.3 0.0 0.0027 17.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 KFM22799.1 - 0.001 19.5 1.0 0.0037 17.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain FtsH_ext PF06480.15 KFM22799.1 - 0.0011 19.3 0.0 0.0024 18.2 0.0 1.5 1 0 0 1 1 1 1 FtsH Extracellular Mg_chelatase PF01078.21 KFM22799.1 - 0.0012 18.3 0.1 0.0092 15.4 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KFM22799.1 - 0.0023 17.7 0.0 0.005 16.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 KFM22799.1 - 0.0054 17.3 0.0 0.027 15.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 KFM22799.1 - 0.0088 16.0 0.0 0.14 12.1 0.0 2.2 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KFM22799.1 - 0.011 15.9 0.2 0.039 14.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KFM22799.1 - 0.015 15.5 0.0 0.037 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFM22799.1 - 0.057 12.9 0.4 0.24 10.9 0.0 2.1 3 0 0 3 3 2 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 KFM22799.1 - 0.059 13.1 0.0 0.3 10.8 0.0 2.2 3 1 0 3 3 1 0 Sigma-54 interaction domain AAA_14 PF13173.6 KFM22799.1 - 0.072 13.1 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain CPT PF07931.12 KFM22799.1 - 0.083 12.7 0.0 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein ABC_tran PF00005.27 KFM22799.1 - 0.09 13.3 0.1 0.27 11.8 0.1 1.7 1 0 0 1 1 1 0 ABC transporter ATPase PF06745.13 KFM22799.1 - 0.21 10.9 1.6 0.92 8.8 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_24 PF13479.6 KFM22799.1 - 0.21 11.3 0.1 0.48 10.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 KFM22799.1 - 0.22 11.0 1.0 0.45 9.9 0.4 1.7 2 0 0 2 2 2 0 PhoH-like protein Zeta_toxin PF06414.12 KFM22799.1 - 0.39 10.0 2.3 0.74 9.1 0.5 2.3 2 1 1 3 3 3 0 Zeta toxin AAA_32 PF13654.6 KFM22799.1 - 0.7 8.6 3.5 14 4.3 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 KFM22799.1 - 0.91 9.1 4.4 0.62 9.6 0.3 2.6 2 1 1 3 3 3 0 AAA domain ATP_synt_H PF05493.13 KFM22800.1 - 6.6e-19 68.1 1.1 7.2e-19 68.0 1.1 1.0 1 0 0 1 1 1 1 ATP synthase subunit H DUF374 PF04028.13 KFM22800.1 - 0.021 14.4 0.0 0.028 14.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF374) DUF1345 PF07077.11 KFM22800.1 - 0.078 12.7 0.5 0.086 12.5 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1345) Ribosomal_S3Ae PF01015.18 KFM22801.1 - 6.3e-93 310.0 2.4 7.5e-93 309.7 2.4 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 KFM22801.1 - 0.026 14.1 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region SUI1 PF01253.22 KFM22801.1 - 0.032 14.8 0.2 0.45 11.1 0.1 2.7 2 0 0 2 2 2 0 Translation initiation factor SUI1 Phage_lysozyme PF00959.19 KFM22801.1 - 0.086 13.3 0.1 0.17 12.4 0.1 1.5 1 1 0 1 1 1 0 Phage lysozyme Viral_Hsp90 PF03225.14 KFM22801.1 - 0.1 11.1 0.0 0.3 9.5 0.0 1.7 2 0 0 2 2 2 0 Viral heat shock protein Hsp90 homologue adh_short PF00106.25 KFM22802.1 - 1.3e-07 31.3 0.1 1.7e-07 30.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM22802.1 - 2.6e-05 23.9 0.0 4.4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase THF_DHG_CYH_C PF02882.19 KFM22802.1 - 0.01 15.1 0.2 0.56 9.5 0.0 2.1 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Complex1_LYR PF05347.15 KFM22803.1 - 0.0013 18.7 0.0 0.0019 18.2 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) PALP PF00291.25 KFM22804.1 - 1.1e-11 44.7 9.1 2.8e-11 43.4 9.1 1.6 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DAHP_synth_1 PF00793.20 KFM22805.1 - 1.3e-53 181.6 0.0 1.7e-53 181.3 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family SNase PF00565.17 KFM22806.1 - 4.7e-12 46.3 0.0 6.1e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Staphylococcal nuclease homologue AAA_12 PF13087.6 KFM22807.1 - 6.5e-47 159.7 0.0 9.8e-47 159.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFM22807.1 - 1.4e-38 133.2 0.2 6e-27 95.1 0.0 2.4 2 1 1 3 3 2 2 AAA domain AAA_30 PF13604.6 KFM22807.1 - 4.5e-09 36.3 0.6 4.5e-09 36.3 0.6 2.8 3 2 0 3 3 2 1 AAA domain R3H PF01424.22 KFM22807.1 - 1.1e-08 34.9 0.0 2.2e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 R3H domain AAA_19 PF13245.6 KFM22807.1 - 2.1e-05 24.9 0.0 6e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KFM22807.1 - 2.2e-05 24.3 0.0 0.067 12.9 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 KFM22807.1 - 0.00026 20.4 0.0 0.00072 18.9 0.0 1.7 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 KFM22807.1 - 0.001 19.5 0.0 0.0018 18.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFM22807.1 - 0.0031 17.9 0.1 0.012 16.0 0.1 2.1 1 0 0 1 1 1 1 AAA ATPase domain DEAD PF00270.29 KFM22807.1 - 0.0032 17.3 0.0 0.0051 16.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_33 PF13671.6 KFM22807.1 - 0.0037 17.4 0.1 0.009 16.2 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KFM22807.1 - 0.0045 16.7 0.0 0.0077 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KFM22807.1 - 0.0067 16.0 2.8 0.043 13.4 2.8 2.2 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KFM22807.1 - 0.013 15.3 0.1 0.045 13.6 0.1 2.0 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 KFM22807.1 - 0.013 15.8 0.9 0.048 13.9 0.4 2.1 2 1 0 2 2 1 0 AAA domain DUF2786 PF10979.8 KFM22807.1 - 0.031 14.2 0.6 0.14 12.1 0.6 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) Helicase_RecD PF05127.14 KFM22807.1 - 0.036 13.9 0.1 0.071 13.0 0.1 1.5 1 0 0 1 1 1 0 Helicase T2SSE PF00437.20 KFM22807.1 - 0.095 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.16 KFM22807.1 - 0.16 11.4 0.0 0.42 10.0 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein AAA_23 PF13476.6 KFM22807.1 - 0.24 11.9 0.0 0.41 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF3783 PF12646.7 KFM22808.1 - 0.053 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3783) Glycolytic PF00274.19 KFM22809.1 - 5.8e-137 456.1 0.0 1.1e-136 455.2 0.0 1.4 1 1 0 1 1 1 1 Fructose-bisphosphate aldolase class-I SQS_PSY PF00494.19 KFM22809.1 - 3.6e-50 170.9 0.2 5.3e-50 170.4 0.2 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase zf-U1 PF06220.12 KFM22810.1 - 1.5e-20 72.6 4.9 1.9e-20 72.3 4.9 1.2 1 0 0 1 1 1 1 U1 zinc finger CLIP1_ZNF PF16641.5 KFM22810.1 - 0.039 13.8 2.2 0.059 13.3 2.2 1.4 1 0 0 1 1 1 0 CLIP1 zinc knuckle Dynein_light PF01221.18 KFM22811.1 - 1.1e-38 131.4 0.2 1.2e-38 131.3 0.2 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 tRNA-synt_1 PF00133.22 KFM22812.1 - 4.3e-31 107.8 0.0 5.1e-24 84.5 0.0 3.2 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KFM22812.1 - 4.5e-13 49.4 0.0 8.8e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KFM22812.1 - 7.5e-12 44.7 0.0 1e-05 24.5 0.0 3.0 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KFM22812.1 - 5.5e-05 22.7 0.0 9.6e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Cas_Cas02710 PF09670.10 KFM22812.1 - 0.12 11.1 0.0 0.21 10.3 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) Kinesin PF00225.23 KFM22813.1 - 2.1e-76 257.0 0.0 3.1e-76 256.4 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFM22813.1 - 6.2e-13 48.9 0.0 9.9e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding PhoH PF02562.16 KFM22813.1 - 0.13 11.6 0.0 2.5 7.5 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein Wbp11 PF09429.10 KFM22814.1 - 3.6e-17 62.5 10.5 5.2e-17 62.0 10.5 1.2 1 0 0 1 1 1 1 WW domain binding protein 11 NpwBP PF12622.7 KFM22814.1 - 3.6e-09 37.3 0.8 3.6e-09 37.3 0.8 2.1 2 0 0 2 2 2 1 mRNA biogenesis factor Mito_carr PF00153.27 KFM22815.1 - 2.7e-75 248.4 1.3 3.5e-24 84.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KFM22815.1 - 5.2 6.2 5.7 26 3.9 0.1 3.1 1 1 1 2 2 2 0 Gammaproteobacterial serine protease SlyX PF04102.12 KFM22816.1 - 0.00043 20.8 5.1 0.00043 20.8 5.1 4.2 2 1 0 2 2 2 1 SlyX DUF745 PF05335.13 KFM22816.1 - 0.011 15.4 12.8 0.011 15.4 12.8 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Cnn_1N PF07989.11 KFM22816.1 - 0.68 10.1 22.4 0.9 9.7 4.7 3.9 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 AT_hook PF02178.19 KFM22816.1 - 0.83 9.7 8.2 2.3 8.4 8.2 1.8 1 0 0 1 1 1 0 AT hook motif Fib_alpha PF08702.10 KFM22816.1 - 1.8 8.8 12.7 32 4.7 4.6 3.3 2 2 1 3 3 3 0 Fibrinogen alpha/beta chain family BST2 PF16716.5 KFM22816.1 - 7.2 7.3 30.8 2 9.1 6.3 3.8 2 1 2 4 4 4 0 Bone marrow stromal antigen 2 TolA_bind_tri PF16331.5 KFM22816.1 - 7.3 6.7 31.5 0.99 9.5 3.4 4.4 2 2 2 4 4 4 0 TolA binding protein trimerisation NAD_binding_2 PF03446.15 KFM22817.1 - 1.5e-30 106.5 0.0 2.6e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KFM22817.1 - 3.3e-25 88.7 0.8 5.4e-25 88.0 0.8 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase GlutR_N PF05201.15 KFM22818.1 - 6.6e-42 142.7 0.0 2.4e-41 140.9 0.0 1.9 2 0 0 2 2 2 1 Glutamyl-tRNAGlu reductase, N-terminal domain Shikimate_DH PF01488.20 KFM22818.1 - 1e-31 109.8 0.0 1.9e-31 109.0 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GlutR_dimer PF00745.20 KFM22818.1 - 1.2e-27 96.2 0.3 2.9e-27 94.9 0.3 1.7 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, dimerisation domain F420_oxidored PF03807.17 KFM22818.1 - 0.00012 22.6 2.2 0.00028 21.4 0.0 2.7 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.6 KFM22818.1 - 0.00014 21.8 0.1 0.00035 20.5 0.1 1.8 1 1 0 1 1 1 1 NAD(P)H-binding OCD_Mu_crystall PF02423.15 KFM22818.1 - 0.00084 18.4 0.0 0.0015 17.5 0.0 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family NAD_binding_2 PF03446.15 KFM22818.1 - 0.0024 18.1 0.0 0.0071 16.5 0.0 1.9 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 KFM22818.1 - 0.0066 16.1 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 KFM22818.1 - 0.036 14.3 0.2 0.11 12.7 0.0 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DUF1640 PF07798.11 KFM22820.1 - 1.1e-52 178.6 10.7 1.3e-52 178.4 10.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Peptidase_S46 PF10459.9 KFM22820.1 - 0.0037 16.0 4.4 0.0043 15.8 4.4 1.1 1 0 0 1 1 1 1 Peptidase S46 DUF848 PF05852.11 KFM22820.1 - 0.14 12.2 5.4 0.32 11.1 0.9 2.3 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) HIP1_clath_bdg PF16515.5 KFM22820.1 - 1.1 10.0 13.8 2.2 8.9 3.2 2.9 1 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ACCA PF03255.14 KFM22820.1 - 1.7 8.5 6.5 4.6 7.1 0.7 2.5 2 1 1 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit PPR PF01535.20 KFM22821.1 - 1.7e-23 81.2 0.7 0.00016 21.7 0.0 5.5 6 0 0 6 6 6 4 PPR repeat PPR_2 PF13041.6 KFM22821.1 - 2.3e-23 82.1 0.0 1.5e-08 34.7 0.0 4.5 2 1 2 4 4 4 4 PPR repeat family PPR_1 PF12854.7 KFM22821.1 - 4e-16 58.4 0.0 0.00023 20.8 0.0 4.8 4 0 0 4 4 4 3 PPR repeat PPR_3 PF13812.6 KFM22821.1 - 6.7e-14 51.7 0.0 2.9e-05 24.1 0.0 4.0 2 1 2 4 4 4 4 Pentatricopeptide repeat domain PPR_long PF17177.4 KFM22821.1 - 1.8e-13 50.4 2.5 0.00013 21.4 0.0 2.6 1 1 3 4 4 4 4 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 KFM22821.1 - 2.9e-07 30.7 8.6 0.084 13.7 0.0 5.3 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFM22821.1 - 3.6e-05 23.5 0.5 0.0087 16.0 0.0 3.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFM22821.1 - 0.0028 18.1 2.9 0.53 10.8 0.0 4.0 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFM22821.1 - 0.0041 17.4 3.2 0.11 12.8 0.0 3.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFM22821.1 - 0.0056 16.5 4.4 0.94 9.4 0.2 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFM22821.1 - 0.0083 16.2 4.9 0.89 9.8 0.2 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat ATP13 PF12921.7 KFM22821.1 - 0.044 13.6 0.0 3.8 7.4 0.0 3.3 1 1 2 3 3 3 0 Mitochondrial ATPase expression TPR_8 PF13181.6 KFM22821.1 - 0.21 11.9 1.1 1.8 9.0 0.2 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFM22821.1 - 0.45 11.2 6.9 6 7.7 0.1 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFM22821.1 - 1 10.0 12.3 3.8 8.2 0.1 4.5 5 2 1 6 6 5 0 Tetratricopeptide repeat LRR_4 PF12799.7 KFM22822.1 - 3e-06 27.5 1.2 0.013 15.9 0.3 2.8 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFM22822.1 - 6e-05 22.7 3.8 0.0009 19.0 1.8 2.8 1 1 2 3 3 3 3 Leucine rich repeat LRRNT_2 PF08263.12 KFM22822.1 - 0.0041 17.4 3.9 0.0041 17.4 3.9 3.8 4 1 0 4 4 4 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 KFM22822.1 - 0.041 14.4 1.8 27 5.8 0.0 3.8 4 0 0 4 4 4 0 Leucine Rich Repeat Pkinase PF00069.25 KFM22823.1 - 6.5e-50 169.9 0.0 1.6e-49 168.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM22823.1 - 8.2e-48 162.9 0.0 3.3e-47 161.0 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 KFM22823.1 - 8.7e-09 35.0 1.7 0.011 15.5 0.1 3.2 2 1 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KFM22823.1 - 5.4e-08 33.0 0.1 0.00056 20.3 0.1 3.3 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM22823.1 - 0.018 15.5 0.4 22 6.1 0.0 4.2 5 0 0 5 5 5 0 Leucine Rich Repeat Filament PF00038.21 KFM22824.1 - 0.0022 17.7 5.1 0.0033 17.1 5.1 1.2 1 0 0 1 1 1 1 Intermediate filament protein HALZ PF02183.18 KFM22824.1 - 0.022 15.0 12.8 0.13 12.5 1.7 3.6 2 2 2 4 4 4 0 Homeobox associated leucine zipper TLE_N PF03920.15 KFM22824.1 - 0.1 12.7 2.2 6.4 6.9 0.4 2.4 1 1 1 2 2 2 0 Groucho/TLE N-terminal Q-rich domain GAS PF13851.6 KFM22824.1 - 0.11 11.9 4.9 0.21 10.9 4.9 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF3450 PF11932.8 KFM22824.1 - 0.27 10.5 7.9 0.58 9.4 7.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) YabA PF06156.13 KFM22824.1 - 0.27 11.9 2.3 6.5 7.4 2.8 2.2 1 1 1 2 2 2 0 Initiation control protein YabA DUF4407 PF14362.6 KFM22824.1 - 0.35 10.2 5.6 0.53 9.6 5.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) bZIP_1 PF00170.21 KFM22824.1 - 0.45 10.6 9.4 5.1 7.3 1.4 2.7 1 1 1 2 2 2 0 bZIP transcription factor Spc7 PF08317.11 KFM22824.1 - 0.63 8.9 11.3 0.34 9.7 3.4 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein ZapB PF06005.12 KFM22824.1 - 0.93 10.0 13.6 5.9 7.4 8.5 3.1 1 1 1 2 2 2 0 Cell division protein ZapB TPR_MLP1_2 PF07926.12 KFM22824.1 - 1.2 9.2 14.5 2.6 8.1 12.5 2.5 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4164 PF13747.6 KFM22824.1 - 2 8.8 11.9 0.8 10.0 3.1 3.1 2 1 0 3 3 3 0 Domain of unknown function (DUF4164) APG6_N PF17675.1 KFM22824.1 - 6.1 7.4 17.1 0.99 9.9 8.4 2.3 1 1 0 1 1 1 0 Apg6 coiled-coil region CBS PF00571.28 KFM22825.1 - 2.3e-19 69.6 5.1 1.2e-14 54.5 1.0 2.9 2 1 0 2 2 2 2 CBS domain Tim17 PF02466.19 KFM22825.1 - 0.0016 18.8 0.4 0.081 13.3 0.4 2.3 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family CRAL_TRIO PF00650.20 KFM22826.1 - 1.5e-08 34.6 0.0 2.4e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain HMG_box_2 PF09011.10 KFM22826.1 - 0.029 14.9 0.2 0.046 14.3 0.2 1.3 1 0 0 1 1 1 0 HMG-box domain FAD_SOX PF18371.1 KFM22826.1 - 0.15 12.4 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase Snf7 PF03357.21 KFM22828.1 - 1.6e-12 47.4 11.3 2e-12 47.1 11.3 1.1 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.14 KFM22828.1 - 0.025 14.5 7.4 0.039 13.9 7.4 1.2 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway DMSP_lyase PF16867.5 KFM22828.1 - 0.21 11.2 0.9 0.45 10.1 0.2 1.9 2 0 0 2 2 2 0 Dimethlysulfonioproprionate lyase DUF4288 PF14119.6 KFM22828.1 - 0.63 10.5 3.4 0.89 10.0 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4288) DUF3886 PF13025.6 KFM22828.1 - 2.6 8.3 7.3 0.27 11.5 2.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) V-SNARE_C PF12352.8 KFM22829.1 - 4.2e-12 46.2 0.0 6.5e-11 42.3 0.0 2.2 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Tim17 PF02466.19 KFM22829.1 - 0.049 14.0 0.8 0.12 12.8 0.8 1.6 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family COBRA1 PF06209.13 KFM22830.1 - 7.1e-34 117.5 5.5 3.4e-16 59.2 0.5 3.3 2 2 1 3 3 3 3 Cofactor of BRCA1 (COBRA1) NUC173 PF08161.12 KFM22830.1 - 0.0038 16.9 0.0 4.3 6.9 0.0 2.7 3 0 0 3 3 3 2 NUC173 domain ABC_tran PF00005.27 KFM22831.1 - 4.3e-36 124.5 0.0 7.7e-18 65.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 KFM22831.1 - 4.9e-13 48.7 5.8 1.1e-12 47.6 5.8 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 KFM22831.1 - 1.8e-12 47.2 2.1 0.0022 17.5 0.0 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFM22831.1 - 4.5e-12 46.4 2.1 0.021 14.6 1.2 4.2 2 2 2 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system Fer4 PF00037.27 KFM22831.1 - 1e-08 34.6 3.4 1e-08 34.6 3.4 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_15 PF13175.6 KFM22831.1 - 1.9e-06 27.9 0.2 0.039 13.7 0.0 3.2 3 1 0 4 4 4 2 AAA ATPase domain AAA PF00004.29 KFM22831.1 - 3.4e-06 27.5 0.0 0.11 12.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KFM22831.1 - 1.1e-05 25.1 0.2 0.06 13.1 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Fer4_6 PF12837.7 KFM22831.1 - 1.5e-05 24.9 2.4 1.5e-05 24.9 2.4 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_10 PF13237.6 KFM22831.1 - 1.9e-05 24.7 8.1 0.00046 20.2 0.1 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_33 PF13671.6 KFM22831.1 - 4.6e-05 23.6 0.0 0.3 11.3 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 KFM22831.1 - 6e-05 23.3 0.1 0.063 13.6 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.6 KFM22831.1 - 6.4e-05 23.4 0.0 0.3 11.4 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain Fer4_2 PF12797.7 KFM22831.1 - 0.00012 21.9 0.7 0.00012 21.9 0.7 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain RsgA_GTPase PF03193.16 KFM22831.1 - 0.00017 21.6 0.1 0.25 11.2 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Fer4_7 PF12838.7 KFM22831.1 - 0.00024 21.6 6.5 0.00071 20.1 0.4 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain TsaE PF02367.17 KFM22831.1 - 0.00025 21.0 0.2 0.12 12.4 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 KFM22831.1 - 0.00031 21.3 3.1 0.046 14.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain SRP54 PF00448.22 KFM22831.1 - 0.00032 20.4 1.4 0.093 12.3 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 KFM22831.1 - 0.00049 20.4 0.2 1.9 8.9 0.0 3.1 3 0 0 3 3 3 1 RNA helicase Rad17 PF03215.15 KFM22831.1 - 0.00089 19.2 0.0 0.17 11.8 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_30 PF13604.6 KFM22831.1 - 0.00091 19.0 1.1 1.6 8.4 0.0 2.8 3 0 0 3 3 3 2 AAA domain NACHT PF05729.12 KFM22831.1 - 0.0012 18.8 0.4 0.18 11.7 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.6 KFM22831.1 - 0.0018 18.1 0.6 0.34 10.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 KFM22831.1 - 0.0022 17.7 0.2 1.7 8.3 0.0 3.4 3 0 0 3 3 3 1 Thymidylate kinase Fer4_9 PF13187.6 KFM22831.1 - 0.0038 17.4 12.2 0.0075 16.4 12.2 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 KFM22831.1 - 0.0045 17.1 12.1 0.0095 16.1 12.1 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_28 PF13521.6 KFM22831.1 - 0.0052 17.0 0.1 2.7 8.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KFM22831.1 - 0.0054 16.3 0.0 0.9 9.0 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region SbcCD_C PF13558.6 KFM22831.1 - 0.0065 16.7 0.0 4.9 7.5 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Fer4_16 PF13484.6 KFM22831.1 - 0.012 16.5 5.8 0.018 15.9 0.2 2.6 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain MMR_HSR1 PF01926.23 KFM22831.1 - 0.022 14.9 0.7 4.3 7.4 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_5 PF07728.14 KFM22831.1 - 0.022 14.7 2.1 1.4 8.9 0.0 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Fer4_8 PF13183.6 KFM22831.1 - 0.039 14.4 4.7 0.13 12.8 0.1 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain MukB PF04310.12 KFM22831.1 - 0.039 13.8 0.6 14 5.4 0.0 3.0 3 0 0 3 3 3 0 MukB N-terminal AAA_18 PF13238.6 KFM22831.1 - 0.04 14.5 0.0 6.7 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KFM22831.1 - 0.043 14.2 0.2 4 7.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KFM22831.1 - 0.066 12.5 0.0 14 4.9 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin NTPase_1 PF03266.15 KFM22831.1 - 0.071 13.0 3.3 7.6 6.4 0.0 3.8 3 1 1 4 4 4 0 NTPase AAA_13 PF13166.6 KFM22831.1 - 0.079 11.6 0.1 1.7 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KFM22831.1 - 0.14 11.3 0.0 11 5.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) CLP1_P PF16575.5 KFM22831.1 - 0.22 11.3 0.5 8.5 6.1 0.0 2.5 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Mg_chelatase PF01078.21 KFM22831.1 - 0.28 10.6 0.7 2.8 7.3 0.0 2.4 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI Fer4_4 PF12800.7 KFM22831.1 - 0.95 10.1 14.9 0.14 12.8 2.9 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_17 PF13534.6 KFM22831.1 - 6.5 7.4 11.7 0.17 12.5 1.5 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain SART-1 PF03343.13 KFM22832.1 - 2.7e-71 241.0 32.0 3.4e-71 240.6 32.0 1.0 1 0 0 1 1 1 1 SART-1 family Glyco_tranf_2_4 PF13704.6 KFM22833.1 - 0.00017 22.0 0.1 0.0056 17.2 0.0 3.0 2 1 1 3 3 3 1 Glycosyl transferase family 2 RRM_1 PF00076.22 KFM22834.1 - 2.9e-10 39.8 0.5 6.1e-10 38.8 0.1 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFM22834.1 - 0.00059 19.4 0.1 0.00067 19.3 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HMGL-like PF00682.19 KFM22835.1 - 2.6e-82 276.3 0.1 4.1e-82 275.7 0.1 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 KFM22835.1 - 4e-23 81.8 0.0 7e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Radical_SAM PF04055.21 KFM22835.1 - 0.13 12.6 0.0 6.5 7.1 0.0 2.6 1 1 1 2 2 2 0 Radical SAM superfamily WD40 PF00400.32 KFM22837.1 - 9.9e-28 95.8 17.7 1.7e-05 25.5 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM22837.1 - 1e-05 25.7 0.1 0.15 12.3 0.0 3.5 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFM22837.1 - 0.12 11.0 2.8 7.9 5.0 0.0 3.4 4 0 0 4 4 4 0 Nucleoporin Nup120/160 Cir_N PF10197.9 KFM22838.1 - 3.6e-09 36.7 12.4 3.6e-09 36.7 12.4 3.6 5 0 0 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR zf-rbx1 PF12678.7 KFM22839.1 - 2.6e-07 30.8 1.4 2.6e-07 30.8 1.4 1.7 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KFM22839.1 - 7.1e-07 29.5 2.9 3.3e-06 27.3 1.4 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 KFM22839.1 - 2.8e-06 27.1 0.4 6.9e-06 25.8 0.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KFM22839.1 - 3e-05 24.0 1.0 3e-05 24.0 1.0 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KFM22839.1 - 4.1e-05 23.2 0.5 0.0022 17.7 0.1 2.6 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KFM22839.1 - 0.00019 21.4 0.4 0.0005 20.0 0.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFM22839.1 - 0.0073 16.1 5.0 0.0073 16.1 5.0 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFM22839.1 - 0.024 14.5 1.3 0.024 14.5 1.3 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KFM22839.1 - 0.039 14.1 0.7 0.095 12.9 0.7 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KFM22839.1 - 0.04 13.5 1.9 0.13 11.9 1.9 1.9 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 KFM22839.1 - 0.076 13.0 3.7 0.057 13.4 1.3 2.1 2 0 0 2 2 2 0 zinc-RING finger domain YdjO PF14169.6 KFM22839.1 - 0.13 12.0 0.3 0.3 10.8 0.3 1.5 1 0 0 1 1 1 0 Cold-inducible protein YdjO zf-C3HC4_4 PF15227.6 KFM22839.1 - 0.14 12.3 2.1 0.37 11.0 2.1 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Aldo_ket_red PF00248.21 KFM22840.1 - 1.3e-54 185.4 0.0 1.4e-54 185.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3531 PF12049.8 KFM22841.1 - 1.8e-48 164.1 0.1 2.4e-48 163.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3531) Vta1 PF04652.16 KFM22842.1 - 1.2e-32 112.9 0.0 1.7e-32 112.4 0.0 1.2 1 0 0 1 1 1 1 Vta1 like Vta1_C PF18097.1 KFM22842.1 - 1e-07 31.5 0.1 2.3e-07 30.4 0.1 1.6 1 0 0 1 1 1 1 Vta1 C-terminal domain SDH_sah PF01972.16 KFM22842.1 - 0.089 11.8 0.0 3.6 6.5 0.0 2.1 2 0 0 2 2 2 0 Serine dehydrogenase proteinase Lon_C PF05362.13 KFM22843.1 - 3.6e-73 245.5 0.0 6.1e-73 244.7 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KFM22843.1 - 2.8e-26 92.7 0.0 4.6e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KFM22843.1 - 3.3e-19 69.6 0.0 7e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 KFM22843.1 - 2.8e-07 30.4 0.0 5.4e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 KFM22843.1 - 2.5e-06 27.5 0.0 6.5e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_PrkA PF08298.11 KFM22843.1 - 4.7e-06 25.8 0.0 8.7e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain AAA_16 PF13191.6 KFM22843.1 - 7e-05 23.3 0.8 0.00026 21.4 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KFM22843.1 - 0.00016 21.5 0.0 0.00039 20.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KFM22843.1 - 0.0002 21.6 0.0 0.0048 17.2 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KFM22843.1 - 0.00089 19.4 0.0 0.0019 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 KFM22843.1 - 0.018 15.6 0.0 0.042 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KFM22843.1 - 0.023 14.4 0.0 0.056 13.2 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 KFM22843.1 - 0.044 13.5 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rnk_N PF14760.6 KFM22843.1 - 0.08 13.4 0.9 0.34 11.4 0.9 2.1 1 0 0 1 1 1 0 Rnk N-terminus AAA_3 PF07726.11 KFM22843.1 - 0.085 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KFM22843.1 - 0.11 12.9 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 KFM22843.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region SKI PF01202.22 KFM22843.1 - 0.2 11.8 0.9 0.84 9.8 0.0 2.4 3 0 0 3 3 3 0 Shikimate kinase CRAL_TRIO PF00650.20 KFM22844.1 - 6.7e-20 71.4 0.0 5.3e-19 68.5 0.0 2.1 1 1 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFM22844.1 - 0.015 15.4 0.0 0.048 13.8 0.0 1.8 1 1 0 1 1 1 0 Divergent CRAL/TRIO domain ATP-synt_DE_N PF02823.16 KFM22845.1 - 0.099 12.6 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 2OG-FeII_Oxy_3 PF13640.6 KFM22846.1 - 4.8e-11 43.4 0.0 8.1e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.13 KFM22846.1 - 0.00065 18.9 0.0 0.00084 18.5 0.0 1.1 1 0 0 1 1 1 1 Poxvirus C4/C10 protein 2OG-FeII_Oxy PF03171.20 KFM22846.1 - 0.029 14.8 0.0 0.064 13.7 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DEAD PF00270.29 KFM22847.1 - 2.7e-48 164.1 0.0 1.5e-47 161.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM22847.1 - 2.6e-32 111.4 0.0 6.5e-32 110.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM22847.1 - 2.2e-05 24.5 0.0 6.4e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NAD_binding_10 PF13460.6 KFM22848.1 - 4.1e-20 72.5 0.2 4.1e-20 72.5 0.2 2.5 2 1 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KFM22848.1 - 0.039 13.4 0.0 2.4 7.5 0.0 2.3 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF1667 PF07892.11 KFM22848.1 - 0.09 12.8 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1667) DUF2052 PF09747.9 KFM22848.1 - 6.7 6.8 20.8 10 6.2 20.8 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF966 PF06136.13 KFM22848.1 - 7 6.3 17.5 8.7 6.0 17.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Acetyltransf_1 PF00583.25 KFM22849.1 - 6.6e-10 39.2 0.1 8.6e-10 38.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFM22849.1 - 1.4e-07 31.5 0.0 2.1e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFM22849.1 - 0.0002 21.7 0.1 0.00031 21.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFM22849.1 - 0.0011 18.8 0.1 0.0038 17.1 0.2 1.8 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.7 KFM22849.1 - 0.11 12.6 0.1 0.15 12.2 0.1 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain WD40 PF00400.32 KFM22850.1 - 1.8e-19 69.7 11.7 7.2e-08 33.0 0.2 6.1 6 1 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.8 KFM22850.1 - 8.3e-06 24.7 0.0 0.17 10.5 0.0 2.8 1 1 2 3 3 3 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KFM22850.1 - 0.0012 19.1 0.0 0.6 10.4 0.0 3.6 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KFM22850.1 - 0.04 12.7 0.0 0.61 8.8 0.0 2.1 2 0 0 2 2 2 0 Nup133 N terminal like Cytochrom_D1 PF02239.16 KFM22850.1 - 0.2 10.2 0.0 0.29 9.6 0.0 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain Ribosomal_S21e PF01249.18 KFM22851.1 - 1.3e-35 121.4 0.0 1.4e-35 121.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Cyclin_N PF00134.23 KFM22852.1 - 1.9e-05 24.4 0.0 0.0027 17.4 0.0 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 KFM22852.1 - 0.026 14.9 0.1 0.094 13.1 0.0 1.9 3 0 0 3 3 3 0 Cyclin C-terminal domain Homeodomain PF00046.29 KFM22854.1 - 8.1e-15 54.4 5.9 3.7e-14 52.3 5.9 2.2 1 0 0 1 1 1 1 Homeodomain HARE-HTH PF05066.13 KFM22854.1 - 5.1e-13 49.2 0.0 9.7e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 HB1, ASXL, restriction endonuclease HTH domain DDT PF02791.17 KFM22854.1 - 2.4e-08 34.1 0.0 6.5e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 DDT domain WSD PF15613.6 KFM22854.1 - 0.017 15.6 0.8 0.11 13.0 0.0 2.6 2 0 0 2 2 2 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif Homeobox_KN PF05920.11 KFM22854.1 - 0.023 14.6 0.2 0.068 13.1 0.2 1.8 1 0 0 1 1 1 0 Homeobox KN domain Hydrolase_4 PF12146.8 KFM22855.1 - 1.2e-10 41.1 0.0 1.8e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFM22855.1 - 1.7e-09 38.6 11.9 1.7e-09 38.6 11.9 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFM22855.1 - 4.9e-07 29.6 0.0 8e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KFM22855.1 - 0.12 12.0 0.1 0.45 10.1 0.0 1.8 2 0 0 2 2 2 0 Putative esterase Heme_oxygenase PF01126.20 KFM22856.1 - 5.5e-32 111.2 0.0 6.7e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Heme oxygenase Mito_carr PF00153.27 KFM22857.1 - 2.4e-59 197.3 2.3 1.8e-20 72.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_60s PF00428.19 KFM22858.1 - 1.4e-09 38.4 1.7 1.5e-08 35.1 0.0 2.0 1 1 1 2 2 2 2 60s Acidic ribosomal protein NADH-u_ox-rdase PF10785.9 KFM22859.1 - 1.3e-22 80.3 0.1 1.5e-22 80.1 0.1 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit DUF2530 PF10745.9 KFM22859.1 - 0.11 12.7 0.6 0.98 9.7 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) EFG_IV PF03764.18 KFM22860.1 - 7.1e-24 83.9 0.0 1.4e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 KFM22860.1 - 8.7e-24 83.4 0.0 2.8e-23 81.8 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU PF00009.27 KFM22860.1 - 1.7e-23 83.2 0.0 4.2e-23 81.9 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KFM22860.1 - 3.9e-13 49.6 0.0 1.1e-12 48.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KFM22860.1 - 3.9e-06 26.9 0.1 9.3e-06 25.7 0.1 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFTUD2 PF16004.5 KFM22860.1 - 0.00069 20.2 0.0 0.0013 19.3 0.0 1.4 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus Mago_nashi PF02792.14 KFM22862.1 - 1e-74 249.4 0.2 1.1e-74 249.2 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein UBA_4 PF14555.6 KFM22863.1 - 6.1e-08 32.3 0.0 1.1e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 KFM22863.1 - 8e-08 32.4 0.0 1.3e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 UBX domain CAF-1_p150 PF11600.8 KFM22863.1 - 0.33 10.6 8.8 0.53 10.0 8.8 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal JmjC PF02373.22 KFM22864.1 - 1.9e-27 96.0 0.0 3.1e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 KFM22864.1 - 5.6e-09 35.8 0.0 1.6e-08 34.3 0.0 1.9 1 0 0 1 1 1 1 jmjN domain Glyco_hydro_47 PF01532.20 KFM22865.1 - 7.2e-147 490.0 0.0 9.6e-147 489.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 IBB PF01749.20 KFM22865.1 - 0.54 10.7 4.5 1.3 9.6 4.5 1.6 1 0 0 1 1 1 0 Importin beta binding domain LRR_6 PF13516.6 KFM22866.1 - 1.3e-08 34.2 0.1 0.00041 20.2 0.0 3.7 2 0 0 2 2 2 2 Leucine Rich repeat LRR_8 PF13855.6 KFM22866.1 - 1.8e-05 24.4 0.0 1.4 8.7 0.0 4.0 3 0 0 3 3 3 2 Leucine rich repeat Lectin_N PF03954.14 KFM22866.1 - 0.075 12.8 0.9 0.17 11.6 0.1 2.0 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain F-box PF00646.33 KFM22866.1 - 0.089 12.7 0.4 0.32 10.9 0.4 2.0 1 1 0 1 1 1 0 F-box domain PEP-utilisers_N PF05524.13 KFM22866.1 - 0.093 12.9 3.3 0.058 13.6 1.2 1.8 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Apolipoprotein PF01442.18 KFM22866.1 - 0.39 10.5 16.0 0.84 9.5 16.0 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain VIR_N PF15912.5 KFM22867.1 - 0.019 14.6 0.9 0.028 14.0 0.9 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal CAP_N PF01213.19 KFM22867.1 - 3.5 7.0 9.5 6.7 6.1 9.5 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SET PF00856.28 KFM22868.1 - 2.9e-19 70.1 0.0 1.1e-18 68.1 0.0 1.9 1 1 0 1 1 1 1 SET domain AWS PF17907.1 KFM22868.1 - 3.8e-16 58.8 7.4 3.8e-16 58.8 7.4 2.2 3 0 0 3 3 3 1 AWS domain Aa_trans PF01490.18 KFM22869.1 - 1.7e-28 99.5 7.3 2.4e-28 99.0 6.6 1.5 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein Thioredoxin PF00085.20 KFM22870.1 - 1.1e-17 63.9 0.0 1.5e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KFM22870.1 - 0.00026 21.3 0.1 0.00044 20.5 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KFM22870.1 - 0.0024 18.3 0.1 0.017 15.5 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KFM22870.1 - 0.015 15.4 0.0 0.027 14.7 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like Redoxin PF08534.10 KFM22870.1 - 0.056 13.2 0.0 0.069 12.9 0.0 1.2 1 0 0 1 1 1 0 Redoxin Thioredoxin_9 PF14595.6 KFM22870.1 - 0.073 12.8 0.0 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin OST3_OST6 PF04756.13 KFM22870.1 - 0.091 12.1 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family RuBisCO_small PF00101.20 KFM22871.1 - 4.9e-40 135.4 0.0 6.6e-40 135.0 0.0 1.2 1 0 0 1 1 1 1 Ribulose bisphosphate carboxylase, small chain RskA PF10099.9 KFM22871.1 - 0.092 13.0 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Nup88 PF10168.9 KFM22872.1 - 0.0034 15.3 0.0 0.0048 14.8 0.0 1.2 1 0 0 1 1 1 1 Nuclear pore component Fer2 PF00111.27 KFM22873.1 - 8.6e-10 38.4 1.5 2.1e-09 37.2 1.5 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain FAD_binding_6 PF00970.24 KFM22873.1 - 3.3e-08 33.8 0.0 7.1e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain GMC_oxred_N PF00732.19 KFM22873.1 - 0.014 14.8 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 GMC oxidoreductase GDI PF00996.18 KFM22873.1 - 0.029 12.9 0.0 0.044 12.3 0.0 1.1 1 0 0 1 1 1 0 GDP dissociation inhibitor RWP-RK PF02042.15 KFM22874.1 - 4.1e-16 58.7 0.0 8.7e-16 57.6 0.0 1.6 1 0 0 1 1 1 1 RWP-RK domain HTH_6 PF01418.17 KFM22874.1 - 0.062 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family Lactamase_B_6 PF16661.5 KFM22875.1 - 1.8e-44 151.5 0.0 2.6e-44 151.0 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 KFM22875.1 - 3.1e-17 63.3 0.0 2.4e-15 57.2 0.0 2.3 1 1 1 2 2 2 2 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 KFM22875.1 - 6.6e-09 36.0 0.0 1.3e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_2 PF12706.7 KFM22875.1 - 1.1e-05 25.1 0.2 2.6e-05 23.8 0.2 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KFM22875.1 - 1.1e-05 25.5 1.2 0.00016 21.7 0.1 2.5 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily eRF1_1 PF03463.15 KFM22876.1 - 9.1e-34 116.2 0.2 1.4e-33 115.6 0.2 1.2 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 KFM22876.1 - 1.6e-21 76.9 0.0 3.3e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.15 KFM22876.1 - 7.6e-11 42.5 0.0 1.7e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 2 Mpv17_PMP22 PF04117.12 KFM22878.1 - 1.5e-20 73.2 0.8 2.2e-20 72.6 0.8 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family Smg4_UPF3 PF03467.15 KFM22879.1 - 4.1e-42 144.2 0.1 7.9e-42 143.2 0.1 1.5 1 0 0 1 1 1 1 Smg-4/UPF3 family PP2C PF00481.21 KFM22880.1 - 3.3e-68 230.1 0.0 9.7e-68 228.6 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KFM22880.1 - 0.01 15.5 0.1 0.024 14.3 0.1 1.7 1 1 0 1 1 1 0 Protein phosphatase 2C Glyco_transf_20 PF00982.21 KFM22881.1 - 1.9e-180 600.6 0.0 2.3e-180 600.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KFM22881.1 - 5.1e-59 199.2 0.0 2.2e-34 118.6 0.0 2.6 2 1 1 3 3 3 2 Trehalose-phosphatase Glyco_trans_1_2 PF13524.6 KFM22881.1 - 0.00072 19.9 0.1 0.0023 18.3 0.1 1.9 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KFM22881.1 - 0.0034 17.8 0.0 0.0076 16.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KFM22881.1 - 0.011 15.3 0.0 0.2 11.2 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 KFM22881.1 - 0.026 14.2 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 Starch synthase catalytic domain Ribosomal_L13e PF01294.18 KFM22882.1 - 4.1e-74 248.3 4.4 5.1e-74 248.0 4.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e US30 PF17624.2 KFM22883.1 - 0.28 10.2 3.7 0.44 9.5 3.7 1.2 1 0 0 1 1 1 0 Family of unknown function Vicilin_N PF04702.12 KFM22883.1 - 2.2 8.1 14.3 5 6.9 14.3 1.6 1 1 0 1 1 1 0 Vicilin N terminal region DUF460 PF04312.13 KFM22884.1 - 0.059 13.1 0.0 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF460) QWRF PF04484.12 KFM22885.1 - 0.066 12.9 2.8 0.061 13.0 1.1 1.7 2 0 0 2 2 2 0 QWRF family bZIP_1 PF00170.21 KFM22885.1 - 0.11 12.6 7.0 0.3 11.2 7.0 1.7 1 0 0 1 1 1 0 bZIP transcription factor Pyr_redox_2 PF07992.14 KFM22887.1 - 9.1e-42 143.3 0.0 7.5e-39 133.7 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFM22887.1 - 2.2e-08 34.6 0.0 1.9e-06 28.3 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFM22887.1 - 0.046 14.0 0.0 11 6.4 0.0 2.7 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Rit1_C PF17184.4 KFM22888.1 - 7.5e-76 255.2 0.0 8.9e-76 254.9 0.0 1.1 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 KFM22888.1 - 2.2e-10 40.8 0.0 3.2e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Rit1 DUSP-like domain TPMT PF05724.11 KFM22889.1 - 3.8e-25 88.9 0.0 5.9e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) DUF3493 PF11998.8 KFM22889.1 - 2.7e-16 59.5 0.0 5.2e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 Low psii accumulation1 / Rep27 Methyltransf_25 PF13649.6 KFM22889.1 - 2.2e-05 25.1 0.0 5.9e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM22889.1 - 0.0048 17.6 0.0 0.011 16.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain YchF-GTPase_C PF06071.13 KFM22890.1 - 9.1e-41 137.9 0.4 5.6e-40 135.4 0.0 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KFM22890.1 - 3.4e-09 36.8 0.0 1.6e-08 34.6 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 KFM22890.1 - 0.091 12.8 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 TGS domain DUF2374 PF09574.10 KFM22890.1 - 0.1 12.4 0.3 0.25 11.2 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (Duf2374) Sdh_cyt PF01127.22 KFM22891.1 - 1.2e-11 44.7 0.1 2e-11 44.0 0.1 1.3 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit zf-4CXXC_R1 PF10497.9 KFM22893.1 - 2.3e-37 127.2 8.2 5e-37 126.1 8.2 1.6 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 TackOD1 PF18551.1 KFM22893.1 - 0.0076 15.9 4.1 0.013 15.1 4.1 1.3 1 0 0 1 1 1 1 Thaumarchaeal output domain 1 DnaJ PF00226.31 KFM22894.1 - 1.4e-09 37.9 0.0 2.2e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Acetyltransf_1 PF00583.25 KFM22895.1 - 2.4e-08 34.2 0.0 3e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFM22895.1 - 5.2e-06 26.4 0.0 7.5e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFM22895.1 - 5.4e-05 23.5 0.0 8.4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFM22895.1 - 0.00016 21.6 0.3 0.00029 20.8 0.3 1.4 1 0 0 1 1 1 1 FR47-like protein PanZ PF12568.8 KFM22895.1 - 0.0051 16.5 0.2 0.0081 15.9 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_8 PF13523.6 KFM22895.1 - 0.018 14.8 0.3 0.026 14.2 0.3 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 KFM22895.1 - 0.13 12.2 0.4 0.22 11.5 0.4 1.3 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_CG PF14542.6 KFM22895.1 - 0.15 12.2 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Pkinase PF00069.25 KFM22896.1 - 1e-24 87.3 0.0 8.8e-20 71.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFM22896.1 - 6.6e-07 28.9 0.0 4.7e-06 26.1 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KFM22896.1 - 8.1e-06 25.9 4.1 1.2e-05 25.4 4.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KFM22896.1 - 0.07 12.7 0.0 0.78 9.3 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Helicase_C PF00271.31 KFM22898.1 - 3.2e-26 91.8 0.0 4.7e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Biotin_lipoyl PF00364.22 KFM22900.1 - 5.5e-08 32.5 0.0 9.2e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme DEC-1_N PF04625.13 KFM22900.1 - 0.00074 18.6 4.0 0.00079 18.5 4.0 1.1 1 0 0 1 1 1 1 DEC-1 protein, N-terminal region RnfC_N PF13375.6 KFM22900.1 - 0.0018 18.2 0.2 0.017 15.0 0.0 2.3 2 1 1 3 3 3 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl_2 PF13533.6 KFM22900.1 - 0.0018 18.0 0.0 0.32 10.9 0.1 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like DUF5525 PF17663.1 KFM22900.1 - 0.19 9.7 7.8 0.25 9.4 7.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5525) PSI_PSAK PF01241.18 KFM22901.1 - 2.7e-18 65.7 0.9 2.7e-18 65.7 0.9 1.5 2 0 0 2 2 2 1 Photosystem I psaG / psaK Ald_Xan_dh_C2 PF02738.18 KFM22902.1 - 1.7e-188 627.6 0.0 2.8e-188 626.9 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 KFM22902.1 - 6.1e-46 156.3 0.0 1.4e-45 155.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Fer2_2 PF01799.20 KFM22902.1 - 2e-32 111.1 0.0 4.3e-32 110.0 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Ald_Xan_dh_C PF01315.22 KFM22902.1 - 1.4e-29 102.7 0.0 3e-29 101.6 0.0 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.17 KFM22902.1 - 6.5e-27 93.7 0.4 2.2e-26 92.0 0.4 2.0 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 KFM22902.1 - 3.2e-09 36.6 2.1 3.3e-09 36.6 0.5 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Peptidase_M24 PF00557.24 KFM22903.1 - 2.3e-52 177.7 0.0 3e-52 177.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KFM22903.1 - 7.6e-32 109.6 0.0 1.2e-31 109.0 0.0 1.2 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Choline_kinase PF01633.20 KFM22904.1 - 7.3e-41 140.1 0.0 1e-40 139.6 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KFM22904.1 - 4.7e-09 36.5 3.2 2.9e-06 27.4 0.0 2.4 2 1 0 2 2 2 2 Phosphotransferase enzyme family EMP70 PF02990.16 KFM22905.1 - 1.7e-155 518.6 8.2 2.2e-155 518.3 8.2 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 TruB_C PF09142.11 KFM22905.1 - 0.17 11.7 0.6 0.4 10.5 0.6 1.6 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal EVC2_like PF12297.8 KFM22905.1 - 4.2 5.9 4.1 21 3.6 0.0 2.2 2 0 0 2 2 2 0 Ellis van Creveld protein 2 like protein DUF599 PF04654.12 KFM22906.1 - 4.1e-29 101.5 3.0 4.7e-29 101.3 3.0 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF599 DUF2254 PF10011.9 KFM22906.1 - 4.7 5.9 7.4 0.67 8.7 0.2 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) Med8 PF10232.9 KFM22908.1 - 3.4e-06 26.8 0.4 4.5e-06 26.4 0.4 1.3 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 TAP42 PF04177.12 KFM22909.1 - 4.6e-54 183.7 1.0 5.5e-54 183.4 1.0 1.0 1 0 0 1 1 1 1 TAP42-like family N2227 PF07942.12 KFM22910.1 - 3.3e-87 292.1 0.0 4.6e-87 291.7 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_11 PF08241.12 KFM22910.1 - 6e-05 23.6 0.0 0.037 14.7 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain TPMT PF05724.11 KFM22910.1 - 0.0072 16.0 0.0 2.9 7.5 0.0 2.2 2 0 0 2 2 2 2 Thiopurine S-methyltransferase (TPMT) Methyltransf_12 PF08242.12 KFM22910.1 - 0.033 14.9 0.0 0.12 13.1 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KFM22910.1 - 0.042 14.6 0.0 8 7.2 0.0 2.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 KFM22910.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Not3 PF04065.15 KFM22911.1 - 2.4e-57 194.0 2.6 3e-57 193.7 2.6 1.1 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 KFM22911.1 - 1.1e-20 74.0 0.0 1.8e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF501 PF04417.12 KFM22911.1 - 0.033 14.0 4.9 0.051 13.4 1.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF501) FAM184 PF15665.5 KFM22911.1 - 0.35 10.6 14.7 1.2 8.9 3.6 2.2 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B 4HB_MCP_1 PF12729.7 KFM22911.1 - 0.39 10.3 5.3 0.13 11.8 1.3 1.9 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction DUF2730 PF10805.8 KFM22911.1 - 0.53 10.4 2.4 0.76 9.9 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) TBCC_N PF16752.5 KFM22911.1 - 0.68 10.4 3.9 0.47 10.9 0.2 2.3 2 1 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain PI3K_P85_iSH2 PF16454.5 KFM22911.1 - 0.78 9.3 8.3 0.39 10.3 3.0 2.3 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain OmpH PF03938.14 KFM22911.1 - 0.78 10.1 9.9 1 9.7 0.2 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 KFM22911.1 - 1.7 9.3 12.0 2 9.1 3.0 3.7 2 2 1 3 3 3 0 SlyX ZapB PF06005.12 KFM22911.1 - 2.1 8.8 9.9 5.6 7.5 2.0 2.7 2 0 0 2 2 2 0 Cell division protein ZapB Syntaxin-6_N PF09177.11 KFM22911.1 - 3.7 8.2 7.9 4.5 7.9 2.8 2.7 2 1 0 2 2 2 0 Syntaxin 6, N-terminal CHASE3 PF05227.13 KFM22911.1 - 5.4 6.9 13.7 4.6 7.1 2.5 2.9 1 1 2 3 3 3 0 CHASE3 domain Zw10 PF06248.13 KFM22911.1 - 5.7 5.4 6.9 4.3 5.8 1.4 2.0 2 0 0 2 2 2 0 Centromere/kinetochore Zw10 Spc7 PF08317.11 KFM22911.1 - 5.7 5.7 15.2 3.8 6.3 1.7 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4670 PF15709.5 KFM22913.1 - 0.0037 16.7 3.2 0.0037 16.7 3.2 1.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4670) Collagen PF01391.18 KFM22913.1 - 2.5 7.9 24.0 2.1 8.2 12.1 2.5 1 1 1 2 2 2 0 Collagen triple helix repeat (20 copies) LigB PF02900.18 KFM22914.1 - 2.5e-36 125.2 0.0 3.2e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase TPR_2 PF07719.17 KFM22915.1 - 3.4e-13 48.6 21.9 6.8e-05 22.7 0.1 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 KFM22915.1 - 1.3e-09 37.5 0.9 0.022 14.4 0.3 4.4 4 0 0 4 4 4 2 TPR repeat TPR_16 PF13432.6 KFM22915.1 - 2.7e-09 37.5 22.2 4.4e-09 36.8 9.3 8.4 6 2 3 9 9 9 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFM22915.1 - 1.6e-08 34.0 5.7 0.0043 16.8 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFM22915.1 - 8.5e-08 32.1 5.4 0.026 14.9 0.0 5.1 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFM22915.1 - 1.1e-06 29.0 15.5 0.00016 22.2 0.7 9.1 4 4 5 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.6 KFM22915.1 - 7.6e-05 23.1 1.4 7.6e-05 23.1 1.4 6.3 2 2 5 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFM22915.1 - 0.0045 17.1 0.0 0.45 10.9 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFM22915.1 - 0.81 10.5 0.1 0.81 10.5 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat 2Fe-2S_thioredx PF01257.19 KFM22917.1 - 4e-55 185.6 0.0 5e-55 185.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DUF1636 PF07845.11 KFM22917.1 - 0.025 15.0 0.0 0.05 14.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1636) TPR_1 PF00515.28 KFM22918.1 - 2.5e-28 96.7 1.6 1.3e-06 27.9 0.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 KFM22918.1 - 2.8e-25 87.7 9.7 1.2e-05 24.9 0.1 6.4 6 0 0 6 6 6 5 TPR repeat TPR_2 PF07719.17 KFM22918.1 - 9.4e-23 78.5 9.7 2.9e-05 23.8 0.1 6.3 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 KFM22918.1 - 1.9e-19 68.2 1.9 0.0023 18.0 0.0 4.8 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.6 KFM22918.1 - 6.5e-19 66.9 17.7 0.0012 19.1 0.3 6.5 7 1 0 7 7 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFM22918.1 - 1.9e-18 65.6 20.4 0.00034 21.2 0.6 8.1 3 2 4 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.6 KFM22918.1 - 4e-13 49.8 39.5 1.6e-06 28.7 5.0 5.9 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFM22918.1 - 1.5e-12 46.6 5.5 0.015 15.3 0.3 5.7 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFM22918.1 - 3.2e-11 43.6 18.0 0.00012 22.5 1.5 4.6 4 1 1 5 5 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFM22918.1 - 7e-11 42.3 13.5 7.1e-05 23.0 0.5 4.7 2 2 4 6 6 6 5 Tetratricopeptide repeat TPR_9 PF13371.6 KFM22918.1 - 2e-06 27.9 12.1 0.022 14.9 0.2 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.6 KFM22918.1 - 2.2e-06 28.0 3.3 2.3 9.1 0.0 6.0 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_20 PF14561.6 KFM22918.1 - 4e-05 23.9 9.0 0.031 14.6 1.9 4.1 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFM22918.1 - 0.00022 21.0 14.5 0.13 12.1 0.5 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 KFM22918.1 - 0.00036 19.9 0.5 0.047 13.2 0.0 3.2 3 0 0 3 3 3 1 SHNi-TPR ANAPC3 PF12895.7 KFM22918.1 - 0.016 15.4 0.8 20 5.5 0.1 3.3 2 2 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.10 KFM22918.1 - 0.053 12.5 0.5 2 7.3 0.0 2.4 1 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) zf-C3HC4_3 PF13920.6 KFM22919.1 - 3.8e-11 42.7 17.0 3.8e-11 42.7 17.0 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFM22919.1 - 1.9e-05 24.4 15.2 1.9e-05 24.4 15.2 3.0 3 1 0 3 3 3 1 Prokaryotic RING finger family 4 EGF_2 PF07974.13 KFM22919.1 - 3.4e-05 24.1 9.6 3.4e-05 24.1 9.6 4.2 4 1 0 4 4 4 1 EGF-like domain DUF2505 PF10698.9 KFM22920.1 - 0.00094 19.3 0.0 0.0016 18.6 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2505) Ysc84 PF04366.12 KFM22921.1 - 8.7e-09 35.2 0.1 1.3e-08 34.6 0.1 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator Ysc84 PF04366.12 KFM22922.1 - 7.6e-09 35.4 0.1 1.2e-08 34.8 0.1 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator CotH PF08757.11 KFM22923.1 - 2.2e-30 106.3 0.0 1.8e-23 83.6 0.0 2.1 2 0 0 2 2 2 2 CotH kinase protein LTD PF00932.19 KFM22923.1 - 1.2e-23 83.6 1.2 7.1e-15 55.3 0.1 3.1 3 0 0 3 3 3 2 Lamin Tail Domain CotH PF08757.11 KFM22924.1 - 7.1e-29 101.3 0.0 1.8e-27 96.8 0.0 2.1 1 1 0 1 1 1 1 CotH kinase protein LTD PF00932.19 KFM22924.1 - 1.9e-11 44.3 0.1 6.2e-08 33.0 0.0 2.5 2 0 0 2 2 2 2 Lamin Tail Domain YEATS PF03366.16 KFM22925.1 - 1.2e-06 28.4 0.0 1.9e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 YEATS family Rhodanese PF00581.20 KFM22925.1 - 0.00083 19.9 0.0 0.0016 18.9 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain DUF455 PF04305.14 KFM22927.1 - 5e-72 242.4 0.0 6.5e-72 242.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) SAICAR_synt PF01259.18 KFM22928.1 - 1.6e-69 234.3 0.0 2e-69 234.0 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase TPR_2 PF07719.17 KFM22929.1 - 6.7e-07 28.9 4.4 4 7.8 0.1 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFM22929.1 - 1.5e-06 28.8 25.8 4e-05 24.2 9.5 4.2 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFM22929.1 - 3.7e-06 27.1 4.6 0.00058 20.1 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFM22929.1 - 0.00029 21.4 19.7 0.0036 18.0 2.8 5.1 3 1 2 5 5 5 2 Tetratricopeptide repeat 60KD_IMP PF02096.20 KFM22929.1 - 0.00069 19.6 0.0 0.009 15.9 0.0 2.1 2 0 0 2 2 2 1 60Kd inner membrane protein TPR_8 PF13181.6 KFM22929.1 - 0.025 14.8 0.0 2.7 8.4 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFM22929.1 - 0.049 14.2 11.0 0.63 10.6 1.4 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_5 PF12688.7 KFM22929.1 - 0.051 13.8 0.3 0.11 12.7 0.3 1.6 1 0 0 1 1 1 0 Tetratrico peptide repeat TPR_1 PF00515.28 KFM22929.1 - 0.054 13.3 0.0 5.2 7.1 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Methyltransf_11 PF08241.12 KFM22930.1 - 4.8e-11 43.2 0.0 8.5e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM22930.1 - 2.2e-10 41.1 0.0 3.8e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM22930.1 - 8.5e-10 39.3 0.0 1.7e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM22930.1 - 4.3e-07 29.9 0.0 6.5e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFM22930.1 - 7e-06 25.5 0.0 9.8e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FA_desaturase_2 PF03405.14 KFM22931.1 - 1.6e-129 431.4 0.0 2.2e-129 431.0 0.0 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Myb_DNA-binding PF00249.31 KFM22931.1 - 9.1e-06 25.8 0.0 2.5e-05 24.4 0.0 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain TEA PF01285.18 KFM22931.1 - 0.17 12.0 0.2 27 4.9 0.0 2.8 2 1 1 3 3 3 0 TEA/ATTS domain Usp PF00582.26 KFM22933.1 - 1.8e-11 44.7 0.4 2.6e-11 44.2 0.4 1.2 1 0 0 1 1 1 1 Universal stress protein family Xpo1 PF08389.12 KFM22934.1 - 8.9e-27 94.0 0.0 7e-26 91.1 0.0 2.5 3 0 0 3 3 3 1 Exportin 1-like protein TrmO_C PF18389.1 KFM22934.1 - 0.034 14.2 0.2 0.09 12.9 0.2 1.7 1 0 0 1 1 1 0 TrmO C-terminal domain Fumble PF03630.14 KFM22935.1 - 2.5e-132 441.1 0.4 3.2e-132 440.7 0.4 1.1 1 0 0 1 1 1 1 Fumble DUF89 PF01937.19 KFM22935.1 - 1.3e-37 129.5 0.0 8e-37 127.0 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function DUF89 TRAM_LAG1_CLN8 PF03798.16 KFM22938.1 - 4.3e-34 118.0 16.7 6.4e-34 117.4 16.7 1.3 1 0 0 1 1 1 1 TLC domain AhpC-TSA PF00578.21 KFM22940.1 - 2.6e-40 137.2 0.0 3.8e-40 136.6 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Vps62 PF06101.11 KFM22940.1 - 1.6e-17 63.0 0.0 2.1e-11 42.8 0.0 2.1 2 0 0 2 2 2 2 Vacuolar protein sorting-associated protein 62 Redoxin PF08534.10 KFM22940.1 - 2.2e-15 56.7 0.0 3e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KFM22940.1 - 9.1e-09 35.0 0.1 2.4e-08 33.7 0.1 1.7 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 KFM22940.1 - 0.13 12.1 0.2 0.25 11.3 0.2 1.3 1 0 0 1 1 1 0 SCO1/SenC Cmc1 PF08583.10 KFM22941.1 - 0.0041 17.1 3.1 0.0055 16.7 3.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like zf-4CXXC_R1 PF10497.9 KFM22942.1 - 2.8e-24 85.2 13.4 4.2e-24 84.6 13.4 1.2 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Rubis-subs-bind PF09273.11 KFM22944.1 - 3.2e-19 69.9 0.1 6.4e-19 68.9 0.1 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding Piezo_RRas_bdg PF12166.8 KFM22945.1 - 4.4e-84 283.2 0.0 6.4e-84 282.7 0.0 1.2 1 0 0 1 1 1 1 Piezo non-specific cation channel, R-Ras-binding domain Mpp10 PF04006.12 KFM22946.1 - 2.3e-99 333.6 8.5 3.3e-99 333.1 0.0 2.4 2 1 0 2 2 2 1 Mpp10 protein TOBE_3 PF12857.7 KFM22946.1 - 0.0015 18.4 0.0 0.004 17.0 0.0 1.7 1 0 0 1 1 1 1 TOBE-like domain DUF4512 PF14975.6 KFM22946.1 - 2.3 9.0 3.5 11 6.9 0.4 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) Mit_KHE1 PF10173.9 KFM22948.1 - 7.1e-24 85.0 0.1 7.1e-24 85.0 0.1 2.8 2 1 1 3 3 3 1 Mitochondrial K+-H+ exchange-related Ribosomal_S8 PF00410.19 KFM22948.1 - 9.9e-20 70.8 0.0 2.1e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S8 FapA PF03961.13 KFM22948.1 - 6.9 5.2 9.0 12 4.4 2.5 2.7 3 0 0 3 3 3 0 Flagellar Assembly Protein A DivIC PF04977.15 KFM22948.1 - 7.3 6.4 14.7 2.1 8.2 5.4 3.6 3 0 0 3 3 3 0 Septum formation initiator DEAD PF00270.29 KFM22949.1 - 2e-36 125.4 0.0 9.4e-36 123.2 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM22949.1 - 3.1e-14 53.3 0.0 5.1e-13 49.3 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 KFM22949.1 - 0.011 15.1 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.15 KFM22949.1 - 0.017 15.2 0.0 0.027 14.5 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PEGSRP PF07623.11 KFM22950.1 - 0.029 14.1 2.7 0.051 13.4 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1584) RmlD_sub_bind PF04321.17 KFM22951.1 - 4.9e-12 45.5 0.0 6.9e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KFM22951.1 - 5.2e-11 42.5 0.0 9e-11 41.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KFM22951.1 - 0.0046 16.1 0.0 0.0073 15.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KFM22951.1 - 0.0084 15.5 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase DUF2232 PF09991.9 KFM22952.1 - 6.1e-15 55.2 15.1 3.3e-14 52.8 15.1 1.8 1 1 0 1 1 1 1 Predicted membrane protein (DUF2232) Paf67 PF10255.9 KFM22953.1 - 7.6e-116 387.4 0.0 9e-116 387.2 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 PCI PF01399.27 KFM22953.1 - 0.0075 16.8 0.5 0.96 10.0 0.1 3.4 3 0 0 3 3 3 1 PCI domain WAC_Acf1_DNA_bd PF10537.9 KFM22955.1 - 1.2e-21 77.1 0.0 2.4e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 KFM22955.1 - 7.6e-12 45.6 1.8 2.2e-09 37.7 1.8 2.7 1 1 0 1 1 1 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif HARE-HTH PF05066.13 KFM22955.1 - 2e-05 24.9 0.0 5.1e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 HB1, ASXL, restriction endonuclease HTH domain CTC1_2 PF15491.6 KFM22955.1 - 0.28 10.5 0.0 0.43 9.8 0.0 1.2 1 0 0 1 1 1 0 CST, telomere maintenance, complex subunit CTC1 PHD_2 PF13831.6 KFM22955.1 - 1.8 8.2 10.6 0.5 10.0 6.2 2.4 2 0 0 2 2 2 0 PHD-finger EamA PF00892.20 KFM22957.1 - 5e-21 75.3 33.4 5.8e-13 49.2 15.5 2.1 2 0 0 2 2 2 2 EamA-like transporter family SLC35F PF06027.12 KFM22957.1 - 0.1 12.1 5.1 0.28 10.6 5.1 1.7 1 1 0 1 1 1 0 Solute carrier family 35 EamA PF00892.20 KFM22958.1 - 1.2e-09 38.5 19.2 1.2e-08 35.2 1.9 3.0 2 1 0 2 2 2 2 EamA-like transporter family DUF1686 PF07937.11 KFM22958.1 - 0.026 14.4 0.8 0.026 14.4 0.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1686) Mg_trans_NIPA PF05653.14 KFM22958.1 - 0.089 11.9 2.0 0.16 11.1 2.0 1.4 1 0 0 1 1 1 0 Magnesium transporter NIPA Rep_fac-A_C PF08646.10 KFM22959.1 - 4e-42 143.4 0.0 6.5e-42 142.7 0.0 1.3 1 0 0 1 1 1 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 KFM22959.1 - 3.3e-29 100.7 0.3 2.2e-28 98.0 0.2 2.2 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 KFM22959.1 - 7.6e-15 54.8 0.4 1.6e-14 53.8 0.4 1.5 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 KFM22959.1 - 1.1e-14 54.2 0.3 1.3e-08 34.7 0.0 4.3 4 0 0 4 4 4 3 OB-fold nucleic acid binding domain DUF5521 PF17659.1 KFM22959.1 - 9.9e-07 27.0 2.9 0.004 15.1 0.0 3.3 2 1 0 2 2 2 2 Family of unknown function (DUF5521) CDC24_OB3 PF17244.2 KFM22959.1 - 0.21 11.3 2.6 14 5.3 0.0 3.6 4 0 0 4 4 4 0 Cell division control protein 24, OB domain 3 His_Phos_2 PF00328.22 KFM22961.1 - 1.1e-88 298.2 0.0 5.7e-48 164.2 0.0 2.3 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Ubie_methyltran PF01209.18 KFM22962.1 - 7.4e-78 261.1 0.0 8.7e-78 260.8 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KFM22962.1 - 1.3e-16 61.0 0.0 3.5e-16 59.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM22962.1 - 6.2e-16 58.9 0.0 1.2e-14 54.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM22962.1 - 2.7e-08 33.8 0.0 7e-08 32.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM22962.1 - 7.8e-08 33.0 0.0 1.3e-07 32.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM22962.1 - 1.9e-07 31.1 0.0 2.6e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KFM22962.1 - 0.026 14.4 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase Vps26 PF03643.15 KFM22963.1 - 7.2e-97 323.7 0.0 8.8e-97 323.4 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 KFM22963.1 - 0.0073 16.4 0.1 0.65 10.0 0.0 3.2 4 0 0 4 4 4 1 Arrestin (or S-antigen), N-terminal domain MFAP1 PF06991.11 KFM22965.1 - 7.4e-64 215.6 14.6 7.4e-64 215.6 14.6 2.2 1 1 1 2 2 2 1 Microfibril-associated/Pre-mRNA processing DUF1501 PF07394.12 KFM22965.1 - 1.5 7.8 6.2 2.9 6.8 6.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Profilin PF00235.19 KFM22966.1 - 6.5e-40 136.3 0.0 7.2e-40 136.2 0.0 1.0 1 0 0 1 1 1 1 Profilin Pex16 PF08610.10 KFM22967.1 - 6.3e-52 176.7 0.0 5.1e-51 173.8 0.0 2.2 1 1 0 1 1 1 1 Peroxisomal membrane protein (Pex16) RRM_1 PF00076.22 KFM22968.1 - 1.2e-20 73.1 0.0 1.9e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Annexin_like PF18411.1 KFM22968.1 - 0.18 12.1 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Annexin-like domain Wtap PF17098.5 KFM22969.1 - 1.4e-06 28.3 11.5 9.9e-06 25.6 5.0 2.6 2 1 0 2 2 2 1 WTAP/Mum2p family GAS PF13851.6 KFM22969.1 - 0.00096 18.6 6.5 0.013 14.9 0.2 2.5 2 1 0 2 2 2 2 Growth-arrest specific micro-tubule binding YabA PF06156.13 KFM22969.1 - 0.003 18.2 3.0 0.98 10.1 0.1 2.3 2 0 0 2 2 2 2 Initiation control protein YabA HALZ PF02183.18 KFM22969.1 - 0.0064 16.7 2.3 0.0064 16.7 2.3 2.5 3 0 0 3 3 3 1 Homeobox associated leucine zipper Fez1 PF06818.15 KFM22969.1 - 0.008 16.6 5.6 0.33 11.4 1.0 2.1 2 0 0 2 2 2 2 Fez1 UPF0184 PF03670.13 KFM22969.1 - 0.02 15.3 0.0 0.045 14.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) CorA PF01544.18 KFM22969.1 - 0.075 12.3 1.4 9.6 5.4 1.2 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein FapA PF03961.13 KFM22969.1 - 0.11 11.0 0.0 0.16 10.5 0.0 1.2 1 1 0 1 1 1 0 Flagellar Assembly Protein A CENP-F_leu_zip PF10473.9 KFM22969.1 - 0.17 11.9 5.2 2.2 8.3 0.2 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PI3K_P85_iSH2 PF16454.5 KFM22969.1 - 0.64 9.6 5.5 1.8 8.1 5.5 1.8 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain HIP1_clath_bdg PF16515.5 KFM22969.1 - 0.8 10.3 12.1 1.4 9.6 2.4 3.2 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 JIP_LZII PF16471.5 KFM22969.1 - 1 9.6 6.0 4.5 7.5 0.7 2.5 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II DUF4201 PF13870.6 KFM22969.1 - 1.2 8.8 9.6 0.94 9.2 1.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) Lebercilin PF15619.6 KFM22969.1 - 1.9 8.1 13.3 0.53 9.9 3.4 2.3 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease HAUS-augmin3 PF14932.6 KFM22969.1 - 4 6.9 8.6 0.63 9.6 0.1 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 ABC_tran_CTD PF16326.5 KFM22969.1 - 8.2 6.8 14.5 4.2 7.7 2.0 3.3 2 1 0 2 2 2 0 ABC transporter C-terminal domain RRM_1 PF00076.22 KFM22970.1 - 1.6e-22 79.1 0.0 2.4e-08 33.7 0.0 4.0 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFM22970.1 - 5.2e-07 29.7 0.0 0.0019 18.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 KFM22970.1 - 3e-05 23.8 0.0 0.071 13.0 0.0 2.9 3 0 0 3 3 3 2 Occluded RNA-recognition motif PHM7_cyt PF14703.6 KFM22970.1 - 0.16 12.2 0.0 29 4.8 0.0 3.1 2 2 2 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter GAF_2 PF13185.6 KFM22971.1 - 1.1e-06 28.9 0.0 1.8e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 KFM22971.1 - 5.7e-05 23.8 0.1 6.9e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 GAF domain Peptidase_M1 PF01433.20 KFM22972.1 - 6.9e-62 208.8 0.0 1.3e-60 204.7 0.0 2.1 1 1 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 KFM22972.1 - 9.3e-35 120.7 0.0 6.4e-30 104.8 0.0 2.3 1 1 1 2 2 2 2 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KFM22972.1 - 1.2e-32 113.6 0.0 1.7e-32 113.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain NAD_binding_10 PF13460.6 KFM22973.1 - 0.0019 18.1 0.0 0.0028 17.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding HrpF PF06266.12 KFM22974.1 - 0.013 15.8 0.0 79 3.7 0.0 3.5 3 0 0 3 3 3 0 HrpF protein CPT_N PF16484.5 KFM22974.1 - 0.022 14.7 0.0 2.7 8.0 0.0 2.6 2 0 0 2 2 2 0 Carnitine O-palmitoyltransferase N-terminus DTW PF03942.15 KFM22974.1 - 0.23 11.1 0.0 0.42 10.3 0.0 1.3 1 0 0 1 1 1 0 DTW domain DUF1118 PF06549.12 KFM22975.1 - 2.7e-31 108.3 8.1 3.4e-31 108.0 8.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1118) CDCA PF18484.1 KFM22976.1 - 0.033 14.1 0.0 0.039 13.8 0.0 1.1 1 0 0 1 1 1 0 Cadmium carbonic anhydrase repeat Na_H_Exchanger PF00999.21 KFM22978.1 - 1.4e-41 142.6 35.5 3.8e-40 137.8 35.5 2.0 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family Pro_isomerase PF00160.21 KFM22978.1 - 1.3e-25 90.5 0.0 2.3e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FeoB_C PF07664.12 KFM22978.1 - 1.4 8.7 4.0 2 8.2 0.1 2.9 3 0 0 3 3 3 0 Ferrous iron transport protein B C terminus B12D PF06522.11 KFM22979.1 - 4.8e-09 35.9 0.0 5.6e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit PAD_porph PF04371.15 KFM22980.1 - 6.1e-112 374.0 0.0 6.8e-112 373.9 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase CN_hydrolase PF00795.22 KFM22981.1 - 2.2e-52 178.0 0.0 4.8e-52 176.9 0.0 1.5 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase PCRF PF03462.18 KFM22982.1 - 2.2e-47 161.4 0.0 4.2e-47 160.5 0.0 1.5 1 0 0 1 1 1 1 PCRF domain RF-1 PF00472.20 KFM22982.1 - 9.4e-33 112.6 0.3 2e-32 111.6 0.0 1.6 2 0 0 2 2 2 1 RF-1 domain ABC_tran_CTD PF16326.5 KFM22982.1 - 0.019 15.2 6.8 0.064 13.5 0.3 3.2 2 2 0 2 2 2 0 ABC transporter C-terminal domain Ald_Xan_dh_C2 PF02738.18 KFM22982.1 - 0.043 12.3 2.3 0.11 10.9 0.3 2.2 2 1 0 2 2 2 0 Molybdopterin-binding domain of aldehyde dehydrogenase BORCS8 PF10167.9 KFM22983.1 - 2.9e-12 46.5 0.0 3.9e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 8 Nre_C PF04895.12 KFM22983.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.4 1 1 0 1 1 1 0 Archaeal Nre, C-terminal Viral_protease PF08715.10 KFM22983.1 - 0.24 10.7 0.0 0.33 10.2 0.0 1.2 1 0 0 1 1 1 0 Papain like viral protease MAGE_N PF12440.8 KFM22983.1 - 0.34 11.6 3.0 0.65 10.7 3.0 1.4 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal Nucleotid_trans PF03407.16 KFM22985.1 - 2.9e-29 102.6 0.0 6.2e-29 101.5 0.0 1.5 2 0 0 2 2 2 1 Nucleotide-diphospho-sugar transferase Nucleotid_trans PF03407.16 KFM22986.1 - 1.9e-19 70.5 0.0 2.7e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase 4HBT PF03061.22 KFM22987.1 - 6.1e-09 36.1 0.0 1.2e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily HIG_1_N PF04588.13 KFM22988.1 - 7.2e-06 26.1 0.0 1.1e-05 25.5 0.0 1.4 1 1 0 1 1 1 1 Hypoxia induced protein conserved region Metallophos PF00149.28 KFM22989.1 - 2.6e-35 122.8 0.3 3.5e-35 122.4 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KFM22989.1 - 0.0012 19.3 0.2 0.0024 18.3 0.2 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 KFM22989.1 - 0.093 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain DEAD PF00270.29 KFM22990.1 - 9.2e-43 146.0 0.2 1.6e-42 145.3 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM22990.1 - 2e-27 95.7 0.0 9.9e-27 93.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM22990.1 - 1.7e-05 24.9 0.0 2.5e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KFM22990.1 - 0.0029 17.9 0.5 0.0055 17.0 0.4 1.7 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KFM22990.1 - 0.016 15.5 0.2 0.079 13.2 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KFM22990.1 - 0.019 14.7 0.2 0.033 13.9 0.2 1.5 1 1 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 KFM22990.1 - 0.046 13.6 0.0 0.077 12.8 0.0 1.4 1 0 0 1 1 1 0 Helicase CbiA PF01656.23 KFM22990.1 - 0.07 13.2 0.0 0.15 12.1 0.0 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain PPR PF01535.20 KFM22991.1 - 0.00011 22.2 0.1 0.24 11.8 0.0 3.0 3 0 0 3 3 3 2 PPR repeat PPR_2 PF13041.6 KFM22991.1 - 0.00039 20.5 0.1 0.0017 18.5 0.0 2.1 2 0 0 2 2 2 1 PPR repeat family NAC PF01849.18 KFM22992.1 - 1.7e-18 66.3 0.1 3.4e-18 65.3 0.0 1.6 2 0 0 2 2 2 1 NAC domain Ndc1_Nup PF09531.10 KFM22993.1 - 0.0026 16.5 5.4 0.0043 15.8 0.0 2.1 1 1 1 2 2 2 1 Nucleoporin protein Ndc1-Nup Tubulin PF00091.25 KFM22996.1 - 5.7e-68 229.0 0.0 8.5e-68 228.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFM22996.1 - 3.6e-40 137.0 0.0 6.7e-40 136.2 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KFM22996.1 - 3.3e-05 24.2 0.0 0.00014 22.2 0.0 1.9 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 KFM22996.1 - 0.034 13.3 0.0 0.054 12.7 0.0 1.3 1 0 0 1 1 1 0 Tubulin like Peptidase_C26 PF07722.13 KFM22997.1 - 3.2e-13 50.0 0.0 7.5e-13 48.7 0.0 1.7 1 1 0 1 1 1 1 Peptidase C26 GATase PF00117.28 KFM22997.1 - 0.002 18.0 0.0 0.0059 16.4 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase class-I NUDIX PF00293.28 KFM22999.1 - 1.4e-16 60.8 0.3 3.6e-16 59.4 0.0 1.9 2 1 0 2 2 2 1 NUDIX domain Fringe PF02434.16 KFM22999.1 - 0.00071 19.1 0.0 0.0029 17.1 0.0 1.8 1 1 0 1 1 1 1 Fringe-like Glyco_trans_2_3 PF13632.6 KFM22999.1 - 0.11 12.3 1.1 0.36 10.7 0.1 2.0 2 0 0 2 2 2 0 Glycosyl transferase family group 2 PNK3P PF08645.11 KFM23000.1 - 2.6e-39 134.5 0.0 3.6e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase HHH_8 PF14716.6 KFM23000.1 - 1.6e-06 28.4 0.0 2.9e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain Ntox34 PF15606.6 KFM23000.1 - 0.048 13.8 0.0 0.16 12.1 0.0 1.8 2 0 0 2 2 2 0 Bacterial toxin 34 TMEM18 PF14770.6 KFM23001.1 - 2.1e-38 131.0 2.8 2.7e-38 130.6 2.8 1.1 1 0 0 1 1 1 1 Transmembrane protein 18 MAP17 PF15807.5 KFM23001.1 - 0.015 15.5 1.1 0.046 13.9 0.3 2.0 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 SPC12 PF06645.13 KFM23002.1 - 4e-26 90.9 0.1 4e-26 90.9 0.1 2.2 3 0 0 3 3 3 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Cellulase PF00150.18 KFM23002.1 - 6.3e-12 45.5 0.0 1.3e-11 44.5 0.0 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4038 PF13204.6 KFM23002.1 - 0.001 18.8 0.0 0.0024 17.6 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF4038) Glyco_hydro_42 PF02449.15 KFM23002.1 - 0.006 16.0 0.0 0.014 14.8 0.0 1.6 1 1 0 1 1 1 1 Beta-galactosidase Glyco_hydro_2_C PF02836.17 KFM23002.1 - 0.033 13.3 0.0 0.069 12.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Acetyltransf_17 PF17668.1 KFM23002.1 - 0.077 13.8 0.0 0.17 12.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain LCM PF04072.14 KFM23003.1 - 3e-19 69.7 0.0 7.9e-19 68.3 0.0 1.7 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Ferritin_2 PF13668.6 KFM23004.1 - 3.4e-42 143.9 0.4 4.9e-42 143.4 0.4 1.2 1 0 0 1 1 1 1 Ferritin-like domain UFD1 PF03152.14 KFM23005.1 - 1.2e-08 34.6 0.0 2.1e-07 30.6 0.0 2.0 1 1 1 2 2 2 2 Ubiquitin fusion degradation protein UFD1 UBX PF00789.20 KFM23005.1 - 7.2e-06 26.1 0.0 1.8e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 UBX domain Pinin_SDK_memA PF04696.13 KFM23005.1 - 2.9 8.0 26.8 0.26 11.3 15.1 2.2 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region FAD_binding_1 PF00667.20 KFM23006.1 - 2.9e-41 141.5 0.0 4.2e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KFM23006.1 - 3.4e-23 82.4 0.0 5.6e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KFM23006.1 - 7.1e-08 33.1 0.0 1.5e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KFM23006.1 - 0.23 11.7 0.0 0.43 10.8 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain LCM PF04072.14 KFM23007.1 - 2e-38 132.2 0.0 3.2e-38 131.6 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase RNase_PH PF01138.21 KFM23007.1 - 4.9e-19 69.1 0.0 8.3e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 PQ-loop PF04193.14 KFM23008.1 - 9.5e-21 73.3 1.8 2.1e-11 43.4 0.2 3.0 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.16 KFM23008.1 - 0.056 13.5 1.1 3.2 7.8 0.2 2.3 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Ras PF00071.22 KFM23009.1 - 3.9e-66 221.6 0.6 4.6e-66 221.4 0.6 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM23009.1 - 4.5e-37 126.9 0.1 6.9e-37 126.3 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM23009.1 - 8.9e-18 64.3 0.1 1.1e-17 64.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFM23009.1 - 3e-07 30.0 0.1 3.5e-07 29.8 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KFM23009.1 - 1.1e-06 28.7 0.2 0.021 14.7 0.0 2.4 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KFM23009.1 - 1.5e-05 25.0 0.1 2.6e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFM23009.1 - 1.8e-05 24.3 0.4 4.2e-05 23.2 0.2 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KFM23009.1 - 8.5e-05 22.1 0.1 0.00011 21.7 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.29 KFM23009.1 - 0.0005 20.5 0.1 0.054 13.9 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 KFM23009.1 - 0.0017 17.9 0.1 0.0052 16.3 0.1 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_5 PF07728.14 KFM23009.1 - 0.018 15.0 0.0 0.053 13.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFM23009.1 - 0.023 15.1 0.0 0.033 14.6 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KFM23009.1 - 0.027 14.8 0.0 0.046 14.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KFM23009.1 - 0.056 13.2 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KFM23009.1 - 0.061 12.8 0.0 0.16 11.5 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region TniB PF05621.11 KFM23009.1 - 0.063 12.7 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein Dioxygenase_N PF04444.14 KFM23009.1 - 0.077 12.9 0.0 0.26 11.2 0.0 1.8 2 0 0 2 2 2 0 Catechol dioxygenase N terminus ABC_tran PF00005.27 KFM23009.1 - 0.088 13.3 0.0 0.15 12.6 0.0 1.5 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.9 KFM23009.1 - 0.13 12.0 0.1 11 5.7 0.0 2.3 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 KFM23009.1 - 0.16 12.4 0.8 0.53 10.7 0.1 2.2 2 1 0 2 2 1 0 RNA helicase Sec23_helical PF04815.15 KFM23010.1 - 1.1e-18 66.9 0.1 1.9e-18 66.2 0.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KFM23010.1 - 1.5e-13 51.3 0.0 2.1e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KFM23010.1 - 1.7e-12 47.2 0.5 3e-12 46.4 0.5 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_trunk PF04811.15 KFM23010.1 - 9.8e-10 38.4 0.0 1.5e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain A2L_zn_ribbon PF08792.10 KFM23010.1 - 0.019 14.7 0.1 0.04 13.7 0.1 1.5 1 0 0 1 1 1 0 A2L zinc ribbon domain zf-RRN7 PF11781.8 KFM23010.1 - 0.54 10.0 2.5 1.6 8.5 2.5 1.8 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 ETF PF01012.21 KFM23011.1 - 0.064 13.1 3.7 2.7 7.8 2.3 2.1 1 1 1 2 2 2 0 Electron transfer flavoprotein domain DUF1441 PF07278.11 KFM23011.1 - 0.17 11.8 0.1 0.3 11.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1441) Rhodanese PF00581.20 KFM23012.1 - 1.1e-08 35.5 0.1 5.1e-08 33.4 0.1 2.1 1 1 0 1 1 1 1 Rhodanese-like domain PIG-P PF08510.12 KFM23013.1 - 5.4e-22 78.0 2.7 9.9e-22 77.1 2.7 1.5 1 0 0 1 1 1 1 PIG-P Mod_r PF07200.13 KFM23013.1 - 6.7e-20 71.7 0.2 1e-19 71.1 0.2 1.3 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein UQ_con PF00179.26 KFM23013.1 - 0.0028 17.3 0.0 0.0051 16.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DPM2 PF07297.12 KFM23013.1 - 0.17 12.2 6.6 0.34 11.2 6.6 1.4 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) ARID PF01388.21 KFM23014.1 - 5.2e-10 39.9 0.0 1.3e-09 38.5 0.0 1.6 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain PUB PF09409.10 KFM23015.1 - 5.8e-12 45.4 0.0 3.4e-11 42.9 0.0 2.1 2 0 0 2 2 2 1 PUB domain zf-C2H2_2 PF12756.7 KFM23015.1 - 0.0063 16.8 5.2 0.43 10.9 0.2 2.3 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) UBA PF00627.31 KFM23015.1 - 0.0097 15.8 0.1 0.044 13.7 0.1 2.2 1 0 0 1 1 1 1 UBA/TS-N domain MCM3AP_GANP PF16769.5 KFM23015.1 - 1.5 7.0 9.6 0.19 9.9 5.7 1.5 2 0 0 2 2 2 0 MCM3AP domain of GANP PYC_OADA PF02436.18 KFM23015.1 - 4.5 7.0 5.3 14 5.3 0.4 2.5 1 1 1 2 2 2 0 Conserved carboxylase domain 2OG-FeII_Oxy_3 PF13640.6 KFM23016.1 - 7.8e-08 33.1 0.0 2e-07 31.8 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KFM23018.1 - 1.3e-09 38.8 0.0 4.8e-09 37.0 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Scytalone_dh PF02982.14 KFM23018.1 - 0.011 15.5 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 Scytalone dehydratase PSI_PSAK PF01241.18 KFM23020.1 - 2.2e-16 59.6 0.2 3.4e-16 59.0 0.2 1.3 1 0 0 1 1 1 1 Photosystem I psaG / psaK COX6B PF02297.17 KFM23023.1 - 3.1e-11 43.3 6.0 4.9e-11 42.7 6.0 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.13 KFM23023.1 - 0.078 13.1 3.5 0.13 12.4 3.5 1.4 1 0 0 1 1 1 0 CHCH domain Ran_BP1 PF00638.18 KFM23024.1 - 2.3e-39 134.4 1.2 3.2e-39 134.0 1.2 1.2 1 0 0 1 1 1 1 RanBP1 domain ThiF PF00899.21 KFM23025.1 - 4.7e-43 147.3 0.0 8.3e-43 146.5 0.0 1.3 1 1 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 KFM23025.1 - 2e-05 24.9 1.0 0.00013 22.2 1.0 2.2 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 KFM23025.1 - 0.055 13.9 0.1 0.13 12.7 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.18 KFM23025.1 - 0.084 13.1 0.1 0.28 11.5 0.0 2.0 1 1 0 1 1 1 0 TrkA-N domain Ank_2 PF12796.7 KFM23026.1 - 3.2e-21 75.7 0.2 1.6e-11 44.6 0.1 3.4 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM23026.1 - 8.7e-19 67.6 3.2 4e-09 36.8 0.2 4.2 3 1 1 4 4 4 3 Ankyrin repeats (many copies) CDP-OH_P_transf PF01066.21 KFM23026.1 - 6.1e-15 55.7 2.0 6.1e-15 55.7 2.0 2.3 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Ank_5 PF13857.6 KFM23026.1 - 2.3e-13 50.1 4.2 6.7e-05 23.1 0.5 4.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM23026.1 - 3.7e-12 45.3 1.1 0.087 13.4 0.0 5.7 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 KFM23026.1 - 7.8e-10 38.8 8.3 0.008 16.6 0.2 5.7 5 0 0 5 5 5 3 Ankyrin repeat UPF0020 PF01170.18 KFM23026.1 - 0.00016 21.4 0.3 0.013 15.2 0.4 2.5 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 DUF3564 PF12087.8 KFM23026.1 - 0.3 11.0 1.3 0.8 9.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3564) RWP-RK PF02042.15 KFM23027.1 - 2.7e-16 59.3 0.0 5.1e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 RWP-RK domain Pentapeptide PF00805.22 KFM23028.1 - 3.7e-26 90.4 7.2 5.3e-10 38.7 1.1 3.3 1 1 3 4 4 4 4 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.6 KFM23028.1 - 1.3e-12 47.6 0.1 1.9e-07 31.1 1.1 2.9 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_4 PF13599.6 KFM23028.1 - 9.2e-11 41.8 0.0 2.8e-08 33.8 0.0 2.3 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) DUF5421 PF17458.2 KFM23028.1 - 0.14 11.6 0.1 0.23 10.8 0.1 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5421) Phage_spike_2 PF18781.1 KFM23028.1 - 0.16 12.0 0.4 0.86 9.7 0.1 2.3 2 1 1 3 3 3 0 Phage spike trimer Helicase_C_2 PF13307.6 KFM23029.1 - 1.8e-47 161.7 0.0 3.2e-47 160.9 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 KFM23029.1 - 2.9e-28 98.7 0.0 5e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 KFM23029.1 - 0.0049 16.6 0.0 0.0091 15.7 0.0 1.3 1 0 0 1 1 1 1 Helical and beta-bridge domain Toprim_Crpt PF13342.6 KFM23029.1 - 0.14 12.1 0.0 0.69 9.9 0.0 2.1 2 0 0 2 2 2 0 C-terminal repeat of topoisomerase Fasciclin PF02469.22 KFM23030.1 - 4.1e-05 23.8 0.0 9.7e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 Fasciclin domain TPT PF03151.16 KFM23032.1 - 9.9e-18 64.5 13.5 1.1e-17 64.3 13.5 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KFM23032.1 - 6.9e-05 23.0 7.2 6.9e-05 23.0 7.2 2.4 2 1 0 2 2 2 1 EamA-like transporter family PRD1_DD PF11087.8 KFM23032.1 - 1.6 8.5 8.6 2.5 7.9 2.8 2.7 2 0 0 2 2 2 0 PRD1 phage membrane DNA delivery Ribosomal_S10 PF00338.22 KFM23033.1 - 6.8e-10 39.1 0.6 1.1e-09 38.4 0.6 1.3 1 1 0 1 1 1 1 Ribosomal protein S10p/S20e DUF4798 PF16055.5 KFM23033.1 - 0.15 12.3 0.0 0.15 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4798) Fasciclin PF02469.22 KFM23036.1 - 4.8e-07 30.1 0.0 0.00068 19.9 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain PLAT PF01477.23 KFM23037.1 - 2.8e-13 50.5 0.0 4.6e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 PLAT/LH2 domain SpoIIE PF07228.12 KFM23037.1 - 0.00017 21.6 0.0 0.00029 20.8 0.0 1.4 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 KFM23037.1 - 0.00051 19.8 0.0 0.00076 19.2 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C zf-A20 PF01754.16 KFM23038.1 - 2.1e-12 46.7 7.6 2.1e-12 46.7 7.6 2.0 2 0 0 2 2 2 1 A20-like zinc finger zf-AN1 PF01428.16 KFM23038.1 - 5.6e-10 39.2 8.3 5.6e-10 39.2 8.3 1.9 2 0 0 2 2 2 1 AN1-like Zinc finger ATG101 PF07855.12 KFM23039.1 - 3.2e-44 150.6 0.4 3.7e-44 150.4 0.4 1.0 1 0 0 1 1 1 1 Autophagy-related protein 101 Y_phosphatase PF00102.27 KFM23040.1 - 0.00033 20.3 0.0 0.00041 20.0 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase PF00102.27 KFM23041.1 - 1.3e-32 113.3 0.0 1.4e-32 113.1 0.0 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFM23041.1 - 0.00022 21.3 0.0 0.00029 20.9 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KFM23041.1 - 0.024 14.5 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFM23041.1 - 0.22 11.6 0.0 0.33 11.0 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate NifU PF01106.17 KFM23042.1 - 2.8e-33 113.9 0.9 1.4e-19 70.0 0.0 2.1 2 0 0 2 2 2 2 NifU-like domain FKBP26_C PF18046.1 KFM23042.1 - 0.12 12.5 0.1 6.7 6.9 0.0 2.5 2 1 0 2 2 2 0 FKBP26_C-terminal OTU PF02338.19 KFM23043.1 - 1.5e-12 48.1 0.1 3.8e-12 46.8 0.0 1.7 2 0 0 2 2 2 1 OTU-like cysteine protease Pex14_N PF04695.13 KFM23043.1 - 1.9e-10 41.7 5.1 1.9e-10 41.7 5.1 4.4 2 2 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF5572 PF17733.1 KFM23043.1 - 2e-10 40.3 0.9 5e-10 39.1 0.9 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5572) Peptidase_C65 PF10275.9 KFM23043.1 - 0.15 11.4 0.7 3.4 7.0 0.0 2.4 2 1 1 3 3 3 0 Peptidase C65 Otubain Phage_Mu_Gam PF07352.12 KFM23043.1 - 0.16 11.9 2.0 0.3 11.0 2.0 1.4 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein Syntaxin-6_N PF09177.11 KFM23043.1 - 6.3 7.4 6.4 8.3 7.0 1.1 2.8 3 0 0 3 3 3 0 Syntaxin 6, N-terminal CorA PF01544.18 KFM23044.1 - 0.9 8.8 3.8 7.3 5.8 0.1 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Pkinase_Tyr PF07714.17 KFM23045.1 - 4.7e-40 137.5 0.0 1.7e-39 135.7 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM23045.1 - 8.6e-39 133.5 0.0 1.6e-38 132.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KFM23045.1 - 0.02 14.2 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFM23045.1 - 0.059 12.7 0.0 0.089 12.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like ABC1 PF03109.16 KFM23045.1 - 0.06 13.5 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 ABC1 family MAGE PF01454.19 KFM23046.1 - 9.1e-16 58.2 0.0 1.1e-15 57.9 0.0 1.1 1 0 0 1 1 1 1 MAGE family DHO_dh PF01180.21 KFM23047.1 - 2.6e-93 312.5 0.0 3e-93 312.3 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.15 KFM23047.1 - 0.17 11.3 0.5 0.26 10.6 0.5 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase CAP_GLY PF01302.25 KFM23049.1 - 1.3e-19 69.9 0.1 2e-19 69.3 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 KFM23049.1 - 2.5e-15 56.3 0.0 1.2e-05 25.5 0.0 4.3 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFM23049.1 - 6.3e-10 38.7 3.5 0.00045 19.9 0.1 4.6 4 1 0 4 4 4 3 Leucine rich repeat LRR_9 PF14580.6 KFM23049.1 - 4.5e-07 29.5 0.0 0.1 12.1 0.0 3.7 2 1 2 4 4 4 2 Leucine-rich repeat DUF5548 PF17702.1 KFM23049.1 - 0.0093 15.7 0.1 0.019 14.7 0.1 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5548) LRR_6 PF13516.6 KFM23049.1 - 0.012 15.6 0.3 21 5.5 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 KFM23049.1 - 0.013 15.9 0.0 30 5.7 0.0 3.8 4 0 0 4 4 4 0 Leucine Rich Repeat Tocopherol_cycl PF14249.6 KFM23050.1 - 0.00025 20.3 2.8 0.0093 15.1 0.2 2.7 3 0 0 3 3 3 2 Tocopherol cyclase Pkinase PF00069.25 KFM23051.1 - 3e-36 125.2 0.0 5.2e-36 124.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM23051.1 - 8.9e-16 57.9 0.0 1.4e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFM23051.1 - 3e-05 24.1 5.3 0.00018 21.5 0.0 3.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KFM23051.1 - 0.00066 19.1 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFM23051.1 - 0.051 12.9 0.0 8.5 5.6 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 KFM23051.1 - 0.094 11.5 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Alanine_zipper PF11839.8 KFM23051.1 - 5 7.6 13.2 10 6.5 13.2 1.5 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein TPR_1 PF00515.28 KFM23052.1 - 2.3e-14 52.5 8.9 0.00036 20.2 0.0 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat PB1 PF00564.24 KFM23052.1 - 5.3e-14 51.9 0.0 1.4e-13 50.5 0.0 1.8 1 0 0 1 1 1 1 PB1 domain TPR_2 PF07719.17 KFM23052.1 - 2.1e-10 39.9 20.2 0.0046 17.0 0.4 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFM23052.1 - 8.3e-10 38.2 0.6 0.0019 17.9 0.0 4.9 4 1 1 5 5 5 3 TPR repeat TPR_8 PF13181.6 KFM23052.1 - 5.6e-07 29.3 2.6 0.006 16.7 0.1 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFM23052.1 - 0.0001 22.4 7.9 0.00016 21.7 0.2 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM23052.1 - 0.017 15.3 1.2 0.054 13.7 1.2 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.10 KFM23052.1 - 0.15 11.1 0.5 0.47 9.4 0.2 1.8 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_17 PF13431.6 KFM23052.1 - 0.28 11.7 0.0 0.28 11.7 0.0 4.2 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF3363 PF11843.8 KFM23052.1 - 1.3 7.9 6.4 5 6.0 0.1 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3363) DUF3458_C PF17432.2 KFM23053.1 - 2.6e-89 299.8 4.5 3.8e-89 299.2 4.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3458_C) ARM repeats Peptidase_M1 PF01433.20 KFM23053.1 - 4.1e-47 160.6 0.0 6.3e-47 160.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain DUF3458 PF11940.8 KFM23053.1 - 4.9e-14 52.5 0.1 1.2e-12 48.1 0.1 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF3458) Ig-like fold Peptidase_M1_N PF17900.1 KFM23053.1 - 4.8e-13 49.7 0.0 7.6e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 KFM23053.1 - 0.043 14.2 0.1 0.21 12.0 0.1 2.2 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Mito_carr PF00153.27 KFM23055.1 - 9.9e-28 95.9 2.6 3.6e-14 52.5 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein NAD_kinase PF01513.21 KFM23056.1 - 0.0056 15.9 0.1 0.0064 15.7 0.1 1.1 1 0 0 1 1 1 1 ATP-NAD kinase NeuB PF03102.14 KFM23056.1 - 0.014 14.8 0.0 0.02 14.4 0.0 1.1 1 0 0 1 1 1 0 NeuB family Glyco_hydro_2_C PF02836.17 KFM23057.1 - 3.8e-84 282.4 0.0 5.7e-84 281.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 KFM23057.1 - 4.7e-53 180.3 0.0 7.5e-53 179.6 0.0 1.3 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 KFM23057.1 - 2.3e-30 105.7 0.0 4.3e-30 104.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain VASt PF16016.5 KFM23057.1 - 5.4e-07 30.1 0.0 1.2e-06 29.0 0.0 1.6 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain Glyco_hydro_2 PF00703.21 KFM23057.1 - 1.7e-06 28.7 0.0 1.3e-05 25.8 0.0 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 2 DUF4981 PF16353.5 KFM23057.1 - 0.0003 21.2 0.0 0.00092 19.6 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function(DUF4981) LSM PF01423.22 KFM23058.1 - 1.2e-15 56.9 0.3 1.5e-15 56.6 0.3 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KFM23058.1 - 0.0013 18.8 0.0 0.0018 18.4 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Sec63 PF02889.16 KFM23059.1 - 6e-131 435.2 0.0 4.1e-82 275.2 0.0 3.2 2 1 1 3 3 3 3 Sec63 Brl domain DEAD PF00270.29 KFM23059.1 - 1.9e-44 151.5 0.0 3.8e-26 91.9 0.0 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 KFM23059.1 - 9.6e-18 64.8 0.0 1.1e-10 41.7 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFM23059.1 - 5.2e-13 49.3 0.0 5.9e-07 29.8 0.0 3.2 2 1 0 2 2 2 2 Helicase conserved C-terminal domain Helicase_PWI PF18149.1 KFM23059.1 - 8.6e-13 48.4 0.0 3.4e-12 46.5 0.0 2.0 2 0 0 2 2 2 1 N-terminal helicase PWI domain AAA_30 PF13604.6 KFM23059.1 - 6.1e-07 29.4 5.7 0.013 15.2 0.1 3.7 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 KFM23059.1 - 6.3e-06 26.5 0.4 0.11 12.8 0.2 3.8 3 1 0 3 3 3 2 AAA domain T2SSE PF00437.20 KFM23059.1 - 0.00059 19.0 0.0 0.84 8.6 0.0 2.7 2 0 0 2 2 2 2 Type II/IV secretion system protein UvrD-helicase PF00580.21 KFM23059.1 - 0.0006 19.4 0.0 0.15 11.5 0.0 2.2 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 KFM23059.1 - 0.0011 19.3 0.1 2.9 8.2 0.1 2.8 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 KFM23059.1 - 0.0064 16.0 0.0 0.66 9.4 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA PF00004.29 KFM23059.1 - 0.016 15.6 0.1 2.7 8.4 0.1 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TACC_C PF05010.14 KFM23059.1 - 0.019 14.8 0.1 0.034 13.9 0.1 1.3 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal AAA_11 PF13086.6 KFM23059.1 - 0.12 12.1 0.0 2.3 7.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain HHA PF05321.11 KFM23059.1 - 3.3 8.1 4.3 11 6.4 0.1 3.3 3 0 0 3 3 3 0 Haemolysin expression modulating protein DUF3611 PF12263.8 KFM23060.1 - 3.9e-29 101.8 7.8 3.7e-16 59.5 4.4 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3611) CDP-OH_P_transf PF01066.21 KFM23061.1 - 8.1e-12 45.7 0.5 8.1e-12 45.7 0.5 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase NUDIX PF00293.28 KFM23062.1 - 6.4e-19 68.3 0.3 7.7e-19 68.0 0.3 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KFM23062.1 - 0.11 12.5 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 NUDIX domain GTP_EFTU PF00009.27 KFM23063.1 - 1.1e-52 178.4 0.0 1.8e-52 177.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 KFM23063.1 - 2.7e-45 152.9 0.6 4.6e-45 152.2 0.6 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 KFM23063.1 - 2.2e-21 75.7 0.0 4.9e-21 74.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KFM23063.1 - 3.9e-08 33.6 0.1 9e-08 32.4 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFM23063.1 - 0.00026 21.1 0.0 0.0013 18.8 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase RF3_C PF16658.5 KFM23063.1 - 0.0022 17.8 0.0 0.0046 16.8 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain EFG_II PF14492.6 KFM23063.1 - 0.0029 17.7 0.0 0.0095 16.0 0.0 1.9 1 1 0 1 1 1 1 Elongation Factor G, domain II Ras PF00071.22 KFM23063.1 - 0.0044 16.6 0.0 0.0091 15.6 0.0 1.4 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KFM23063.1 - 0.052 13.0 0.0 0.22 11.0 0.0 2.1 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit PsbP PF01789.16 KFM23064.1 - 1.8e-10 41.2 0.0 3.9e-10 40.1 0.0 1.5 1 1 0 1 1 1 1 PsbP NDUF_B7 PF05676.13 KFM23065.1 - 2.6e-23 81.5 4.7 2.8e-23 81.4 4.7 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 KFM23065.1 - 0.00025 21.0 3.0 0.00027 20.9 3.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like zf-TAZ PF02135.16 KFM23066.1 - 0.0048 17.3 1.5 0.0055 17.1 1.5 1.1 1 0 0 1 1 1 1 TAZ zinc finger MCM_OB PF17207.3 KFM23066.1 - 0.0071 16.2 1.8 0.0077 16.1 1.8 1.1 1 0 0 1 1 1 1 MCM OB domain Eclosion PF04736.12 KFM23066.1 - 0.022 14.4 0.5 0.023 14.4 0.5 1.1 1 0 0 1 1 1 0 Eclosion hormone Kunitz_BPTI PF00014.23 KFM23067.1 - 1e-18 67.3 5.1 1e-18 67.3 5.1 2.6 3 0 0 3 3 3 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Paramecium_SA PF01508.16 KFM23067.1 - 0.023 15.1 3.6 0.023 15.1 3.6 3.4 3 1 0 3 3 3 0 Paramecium surface antigen domain DUF647 PF04884.14 KFM23068.1 - 2.3e-64 217.3 0.2 2.9e-64 217.0 0.2 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Ribosomal_L21p PF00829.21 KFM23069.1 - 2.8e-31 107.8 0.1 3.4e-31 107.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein O-FucT PF10250.9 KFM23070.1 - 8.2e-14 52.0 0.0 1.4e-11 44.7 0.0 2.7 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase GCV_T PF01571.21 KFM23071.1 - 8.3e-11 41.7 0.0 2e-10 40.5 0.0 1.6 1 1 0 1 1 1 1 Aminomethyltransferase folate-binding domain Epimerase PF01370.21 KFM23072.1 - 4.2e-12 46.0 0.0 8e-11 41.9 0.0 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFM23072.1 - 7.9e-11 42.2 0.0 1.2e-09 38.4 0.0 2.3 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KFM23072.1 - 4.7e-09 36.1 0.0 6.9e-05 22.4 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KFM23072.1 - 3.6e-06 26.7 0.0 7.1e-06 25.7 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family Glyco_transf_4 PF13439.6 KFM23072.1 - 0.02 14.9 0.2 0.068 13.2 0.0 1.9 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Glyco_transf_28 PF03033.20 KFM23072.1 - 0.022 14.8 0.1 0.05 13.6 0.1 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain TrkA_N PF02254.18 KFM23072.1 - 0.037 14.3 0.0 0.094 13.0 0.0 1.6 1 1 0 1 1 1 0 TrkA-N domain NAD_binding_2 PF03446.15 KFM23072.1 - 0.13 12.4 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Ribosomal_L3 PF00297.22 KFM23073.1 - 6.8e-16 58.2 1.3 1.8e-15 56.8 0.1 2.2 2 1 1 3 3 3 1 Ribosomal protein L3 Cyclin_N PF00134.23 KFM23074.1 - 6.7e-25 87.3 0.0 4.6e-24 84.6 0.0 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFM23074.1 - 4.6e-11 42.8 1.0 8.2e-11 42.0 0.3 1.7 2 0 0 2 2 2 1 Cyclin, C-terminal domain DUF1376 PF07120.11 KFM23074.1 - 0.037 14.3 0.0 1.1 9.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1376) TFIIB_C_1 PF18542.1 KFM23074.1 - 0.34 11.0 1.1 1.2 9.3 0.0 2.0 2 0 0 2 2 2 0 Transcription factor IIB C-terminal module 1 Helicase_C PF00271.31 KFM23075.1 - 3.5e-17 62.7 0.0 6.4e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KFM23075.1 - 5.4e-16 58.7 0.0 1.2e-15 57.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KFM23075.1 - 1.7e-11 44.3 1.7 2e-11 44.1 0.1 1.9 2 0 0 2 2 2 1 Helicase associated domain (HA2) RWD PF05773.22 KFM23075.1 - 6.7e-11 42.5 0.0 1.1e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 RWD domain DND1_DSRM PF14709.7 KFM23075.1 - 0.006 16.8 0.6 0.014 15.6 0.0 2.0 2 0 0 2 2 2 1 double strand RNA binding domain from DEAD END PROTEIN 1 UBA_6 PF18039.1 KFM23075.1 - 0.14 12.1 0.0 0.41 10.6 0.0 1.7 1 0 0 1 1 1 0 UBA-like domain Aminotran_5 PF00266.19 KFM23077.1 - 1.7e-88 297.1 0.0 2.2e-88 296.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KFM23077.1 - 1.1e-05 24.9 0.0 1.4e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KFM23077.1 - 0.021 14.2 0.1 0.035 13.4 0.1 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 KFM23077.1 - 0.03 13.0 0.0 0.06 12.1 0.0 1.4 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain CCB2_CCB4 PF11152.8 KFM23079.1 - 4.1e-13 49.1 0.1 4.9e-13 48.8 0.1 1.0 1 0 0 1 1 1 1 Cofactor assembly of complex C subunit B, CCB2/CCB4 UPF0051 PF01458.17 KFM23080.1 - 4.1e-53 180.3 0.7 5.4e-53 179.9 0.7 1.1 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) DUF3755 PF12579.8 KFM23082.1 - 2.5e-09 36.6 0.7 5.7e-09 35.5 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3755) GIT1_C PF12205.8 KFM23083.1 - 0.0099 16.0 0.1 0.012 15.7 0.1 1.1 1 0 0 1 1 1 1 G protein-coupled receptor kinase-interacting protein 1 C term Snapin_Pallidin PF14712.6 KFM23083.1 - 0.047 14.1 0.0 0.058 13.8 0.0 1.1 1 0 0 1 1 1 0 Snapin/Pallidin BLOC1S3 PF15753.5 KFM23083.1 - 0.15 12.2 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 WD40 PF00400.32 KFM23084.1 - 0.00058 20.6 7.2 11 7.1 0.0 5.2 5 1 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM23084.1 - 0.0097 16.2 0.0 0.029 14.7 0.0 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nup88 PF10168.9 KFM23084.1 - 0.26 9.0 0.0 0.35 8.6 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore component Med26 PF08711.11 KFM23086.1 - 2.8e-08 33.6 0.0 4.6e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 TFIIS helical bundle-like domain zf-CCCH PF00642.24 KFM23086.1 - 0.05 13.5 4.7 0.091 12.7 4.7 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KFM23086.1 - 0.11 12.3 4.6 0.19 11.5 4.6 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KFM23086.1 - 0.21 11.7 6.6 0.36 10.9 6.6 1.4 1 0 0 1 1 1 0 Zinc finger domain CD20 PF04103.15 KFM23086.1 - 0.28 11.2 0.5 0.5 10.4 0.5 1.3 1 0 0 1 1 1 0 CD20-like family zf-CCCH_2 PF14608.6 KFM23086.1 - 1.7 9.3 5.6 5 7.7 5.6 1.8 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-CXXC PF02008.20 KFM23086.1 - 2.1 8.4 7.2 0.33 11.0 2.2 2.1 2 0 0 2 2 2 0 CXXC zinc finger domain Pkinase PF00069.25 KFM23088.1 - 4.2e-61 206.6 0.0 5e-61 206.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM23088.1 - 1.1e-16 60.9 0.0 1.5e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFM23088.1 - 1.6e-07 31.5 0.1 3.9e-06 27.0 0.3 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KFM23088.1 - 0.0032 16.8 0.0 0.0048 16.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFM23088.1 - 0.0094 14.8 0.3 0.023 13.5 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Choline_kinase PF01633.20 KFM23088.1 - 0.038 13.6 0.0 0.07 12.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase bZIP_1 PF00170.21 KFM23089.1 - 7.4e-07 29.2 13.5 1.1e-06 28.6 13.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFM23089.1 - 0.0075 16.3 14.2 0.013 15.6 14.2 1.4 1 0 0 1 1 1 1 Basic region leucine zipper PolyA_pol PF01743.20 KFM23089.1 - 0.085 13.3 0.3 0.13 12.7 0.3 1.2 1 0 0 1 1 1 0 Poly A polymerase head domain DUF4200 PF13863.6 KFM23089.1 - 0.095 13.1 4.4 0.14 12.6 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DNA_photolyase PF00875.18 KFM23090.1 - 1.2e-27 96.9 0.0 2.6e-27 95.9 0.0 1.5 1 0 0 1 1 1 1 DNA photolyase CAF1 PF04857.20 KFM23091.1 - 3.2e-18 66.0 2.2 1.5e-08 34.2 0.0 2.7 2 1 0 2 2 2 2 CAF1 family ribonuclease Apc13p PF05839.11 KFM23092.1 - 0.00043 20.4 0.4 0.00078 19.6 0.4 1.6 1 1 0 1 1 1 1 Apc13p protein SAC3_GANP PF03399.16 KFM23093.1 - 3.5e-07 29.9 0.0 4.7e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 SAC3/GANP family SRP_TPR_like PF17004.5 KFM23094.1 - 1.7e-16 60.2 3.6 1.1e-15 57.7 3.2 2.2 2 1 0 2 2 2 1 Putative TPR-like repeat TPR_19 PF14559.6 KFM23094.1 - 1.3e-11 44.9 13.7 0.00013 22.4 0.0 4.1 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.17 KFM23094.1 - 2.8e-08 33.2 11.9 0.3 11.3 2.2 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFM23094.1 - 3.5e-07 29.8 2.0 0.63 10.0 0.0 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFM23094.1 - 3.9e-07 30.3 6.7 0.039 14.2 0.8 4.5 3 1 2 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM23094.1 - 6e-07 29.6 5.2 0.018 15.3 1.3 3.3 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KFM23094.1 - 8.9e-07 28.7 1.0 0.1 12.9 0.0 4.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 KFM23094.1 - 1.8e-06 27.4 4.3 0.0032 16.7 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFM23094.1 - 3.5e-06 27.3 8.7 0.15 12.8 1.3 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFM23094.1 - 7.6e-06 25.9 1.3 0.92 10.0 0.0 4.7 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFM23094.1 - 2e-05 25.2 14.5 0.11 13.1 1.7 4.5 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFM23094.1 - 4.4e-05 23.1 0.8 0.47 10.2 0.4 4.2 4 0 0 4 4 4 1 TPR repeat TPR_14 PF13428.6 KFM23094.1 - 4.9e-05 23.8 10.6 0.23 12.4 0.0 4.9 1 1 5 6 6 6 2 Tetratricopeptide repeat TPR_20 PF14561.6 KFM23094.1 - 0.00086 19.6 8.5 0.13 12.6 0.5 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat BTAD PF03704.17 KFM23094.1 - 0.0011 19.4 0.1 0.0011 19.4 0.1 3.4 1 1 3 4 4 4 1 Bacterial transcriptional activator domain TPR_7 PF13176.6 KFM23094.1 - 0.0038 17.1 6.1 0.99 9.6 0.3 3.7 5 0 0 5 5 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFM23094.1 - 0.0055 16.7 1.0 0.33 11.1 0.0 3.1 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 KFM23094.1 - 0.02 15.0 7.7 0.12 12.5 0.0 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KFM23094.1 - 0.029 15.0 12.9 20 6.2 0.1 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat YdfA_immunity PF12127.8 KFM23094.1 - 0.04 13.0 0.1 0.073 12.1 0.1 1.4 1 0 0 1 1 1 0 SigmaW regulon antibacterial TPR_10 PF13374.6 KFM23094.1 - 0.17 11.8 2.6 17 5.4 0.2 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat PP2C PF00481.21 KFM23098.1 - 1.6e-50 172.2 0.0 1.8e-50 172.0 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KFM23098.1 - 3.2e-08 33.5 0.2 7.4e-08 32.3 0.2 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KFM23098.1 - 0.0024 17.8 0.3 0.014 15.3 0.3 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) LZ3wCH PF18517.1 KFM23099.1 - 2.9e-09 36.9 0.7 7.4e-09 35.6 0.1 2.1 2 0 0 2 2 2 1 Leucine zipper with capping helix domain TBPIP PF07106.13 KFM23099.1 - 3e-08 33.5 0.1 6.7e-08 32.4 0.1 1.6 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain DUF4693 PF15764.5 KFM23099.1 - 0.0084 15.7 2.1 0.011 15.4 2.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4693) Phage_GP20 PF06810.11 KFM23099.1 - 0.012 15.4 8.9 0.02 14.7 5.5 2.3 2 0 0 2 2 2 0 Phage minor structural protein GP20 Atg14 PF10186.9 KFM23099.1 - 0.06 12.4 1.4 0.081 12.0 1.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Tup_N PF08581.10 KFM23099.1 - 0.077 13.3 3.3 0.15 12.4 3.3 1.5 1 0 0 1 1 1 0 Tup N-terminal CCP_MauG PF03150.14 KFM23099.1 - 0.096 13.3 0.3 0.2 12.3 0.3 1.7 1 1 0 1 1 1 0 Di-haem cytochrome c peroxidase Spectrin PF00435.21 KFM23099.1 - 0.16 12.5 8.0 0.47 11.0 6.4 2.5 1 1 1 2 2 2 0 Spectrin repeat Swi5 PF07061.11 KFM23099.1 - 0.76 9.9 7.2 1.6e+02 2.4 7.2 2.9 1 1 0 1 1 1 0 Swi5 ArfGap PF01412.18 KFM23100.1 - 1.4e-33 115.4 0.0 2.3e-33 114.7 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf IMS PF00817.20 KFM23101.1 - 2e-33 115.5 0.2 2.3e-22 79.6 0.0 2.3 1 1 1 2 2 2 2 impB/mucB/samB family IMS_C PF11799.8 KFM23101.1 - 7.5e-10 39.5 0.0 1.2e-09 38.9 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain UBM PF14377.6 KFM23101.1 - 0.0037 16.7 0.6 0.015 14.7 0.6 2.1 1 0 0 1 1 1 1 Ubiquitin binding region DUF1805 PF08827.11 KFM23101.1 - 0.033 14.5 0.1 0.14 12.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1805) PP2C PF00481.21 KFM23102.1 - 8.8e-12 45.2 0.0 1.3e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C eIF-5a PF01287.20 KFM23103.1 - 6.5e-28 96.6 0.3 1.2e-27 95.8 0.3 1.4 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 KFM23103.1 - 0.013 15.5 0.1 0.024 14.7 0.1 1.5 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain Mob1_phocein PF03637.17 KFM23103.1 - 0.016 15.2 0.0 0.67 10.0 0.0 2.1 2 0 0 2 2 2 0 Mob1/phocein family DUF3456 PF11938.8 KFM23104.1 - 6e-16 59.3 0.4 1.4e-15 58.2 0.4 1.5 1 1 0 1 1 1 1 TLR4 regulator and MIR-interacting MSAP ELYS PF13934.6 KFM23105.1 - 5.1e-12 46.2 2.9 3.2e-11 43.6 2.1 2.2 2 0 0 2 2 2 1 Nuclear pore complex assembly ENT PF03735.14 KFM23107.1 - 1.1e-10 41.5 1.0 3.6e-10 39.8 0.2 2.0 2 0 0 2 2 2 1 ENT domain Tic110 PF16940.5 KFM23108.1 - 6.7e-161 536.6 7.0 3.1e-158 527.9 0.6 2.9 3 0 0 3 3 3 2 Chloroplast envelope transporter Nexin_C PF08628.12 KFM23108.1 - 0.07 13.7 0.6 0.31 11.6 0.4 2.2 2 0 0 2 2 2 0 Sorting nexin C terminal Nas2_N PF18265.1 KFM23110.1 - 7.5e-23 80.3 0.0 9.5e-23 79.9 0.0 1.1 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 KFM23110.1 - 2e-07 30.7 0.2 4.2e-07 29.7 0.2 1.7 1 1 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFM23110.1 - 9.3e-07 29.1 0.0 1.6e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFM23110.1 - 0.0051 17.1 0.0 0.0087 16.4 0.0 1.4 1 0 0 1 1 1 1 PDZ domain YdjC PF04794.12 KFM23110.1 - 0.022 14.8 0.1 0.031 14.3 0.1 1.2 1 0 0 1 1 1 0 YdjC-like protein EF-hand_1 PF00036.32 KFM23111.1 - 8.5e-12 43.7 0.8 6.9e-05 22.1 0.1 2.8 2 1 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KFM23111.1 - 9e-12 45.3 0.1 2.4e-11 43.9 0.1 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KFM23111.1 - 7.3e-10 38.0 1.2 0.0004 20.1 0.0 3.2 2 1 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 KFM23111.1 - 1.3e-08 34.5 1.0 0.00061 19.6 0.0 2.8 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KFM23111.1 - 1.5e-08 33.8 5.4 0.00078 18.8 0.1 3.2 2 1 1 3 3 3 2 EF hand EF-hand_11 PF08976.11 KFM23111.1 - 0.0007 20.4 0.0 0.0012 19.7 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain DUF5580 PF17743.1 KFM23111.1 - 0.1 11.1 0.0 0.16 10.5 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5580) EF-hand_4 PF12763.7 KFM23111.1 - 0.14 12.2 0.1 0.61 10.1 0.1 1.9 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand DUF2207 PF09972.9 KFM23111.1 - 0.15 10.8 0.2 0.18 10.5 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PspA_IM30 PF04012.12 KFM23113.1 - 7.5e-49 166.3 24.1 9.3e-49 166.0 24.1 1.1 1 0 0 1 1 1 1 PspA/IM30 family Spc7 PF08317.11 KFM23113.1 - 0.19 10.6 16.5 0.26 10.1 16.2 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein Syntaxin-6_N PF09177.11 KFM23113.1 - 0.6 10.7 6.5 4.8 7.8 3.6 3.0 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Cep57_CLD_2 PF14197.6 KFM23113.1 - 1.1 9.4 10.1 0.18 11.9 5.3 2.3 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Prefoldin_2 PF01920.20 KFM23113.1 - 4 7.4 11.7 0.64 10.0 3.8 2.6 2 1 0 2 2 2 0 Prefoldin subunit Myb_DNA-binding PF00249.31 KFM23114.1 - 0.0047 17.1 0.0 0.0099 16.1 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain CLP_protease PF00574.23 KFM23115.1 - 8.8e-48 162.6 0.3 1.1e-47 162.3 0.3 1.0 1 0 0 1 1 1 1 Clp protease Fe_dep_repr_C PF02742.15 KFM23115.1 - 0.0086 16.1 0.1 0.014 15.5 0.1 1.2 1 0 0 1 1 1 1 Iron dependent repressor, metal binding and dimerisation domain Peptidase_S49 PF01343.18 KFM23115.1 - 0.038 13.9 0.0 0.071 13.1 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S49 Ribosomal_L22 PF00237.19 KFM23116.1 - 3.3e-23 81.9 0.0 4.1e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e ANTH PF07651.16 KFM23116.1 - 0.23 10.4 0.0 0.38 9.7 0.0 1.3 2 0 0 2 2 2 0 ANTH domain Peptidase_M17 PF00883.21 KFM23117.1 - 1.3e-47 162.6 0.0 1.7e-47 162.2 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain ABC_tran PF00005.27 KFM23119.1 - 3e-38 131.4 0.0 1.5e-22 80.6 0.0 2.2 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 KFM23119.1 - 5.4e-15 55.3 14.1 4.9e-11 42.3 16.1 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 KFM23119.1 - 1.9e-14 54.2 0.0 2e-07 31.1 0.0 3.2 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system RRM_1 PF00076.22 KFM23119.1 - 2.6e-13 49.6 0.0 6e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_15 PF13175.6 KFM23119.1 - 3.7e-05 23.6 0.0 4.4 6.9 0.0 3.1 3 0 0 3 3 3 3 AAA ATPase domain AAA_16 PF13191.6 KFM23119.1 - 5.7e-05 23.6 0.0 0.15 12.4 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 KFM23119.1 - 5.9e-05 23.7 0.2 0.52 10.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KFM23119.1 - 9.3e-05 22.2 0.0 0.72 9.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KFM23119.1 - 0.0049 17.2 0.2 5.3 7.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 KFM23119.1 - 0.0058 16.4 0.0 4.7 6.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KFM23119.1 - 0.0064 16.2 0.0 6.5 6.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KFM23119.1 - 0.0068 15.7 0.0 4.2 6.6 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin SRP54 PF00448.22 KFM23119.1 - 0.0079 15.8 0.8 4.8 6.8 0.1 2.6 3 0 0 3 3 3 2 SRP54-type protein, GTPase domain IstB_IS21 PF01695.17 KFM23119.1 - 0.012 15.4 0.0 43 3.8 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein SMC_N PF02463.19 KFM23119.1 - 0.016 14.7 0.0 4.5 6.7 0.0 3.0 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 KFM23119.1 - 0.025 13.6 0.0 12 4.8 0.0 2.9 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_19 PF13245.6 KFM23119.1 - 0.05 13.9 0.0 19 5.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KFM23119.1 - 0.064 13.2 0.0 16 5.4 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain Mg_chelatase PF01078.21 KFM23119.1 - 0.091 12.1 0.0 16 4.8 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_27 PF13514.6 KFM23119.1 - 0.15 11.7 0.0 21 4.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KFM23119.1 - 0.23 11.9 1.2 33 4.9 0.1 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF743 PF05332.11 KFM23120.1 - 0.1 12.6 0.2 0.16 12.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF743) RCC1 PF00415.18 KFM23122.1 - 1.3e-59 198.6 16.6 1.6e-11 44.6 0.1 7.4 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFM23122.1 - 5.5e-34 115.3 33.1 3e-09 36.4 0.1 7.5 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat PHD PF00628.29 KFM23123.1 - 1.8e-10 40.6 8.4 3.4e-10 39.6 8.4 1.5 1 0 0 1 1 1 1 PHD-finger zf-ribbon_3 PF13248.6 KFM23123.1 - 0.0012 18.2 2.0 0.046 13.2 0.1 2.6 2 0 0 2 2 2 2 zinc-ribbon domain zf-RING_2 PF13639.6 KFM23123.1 - 9.7 6.6 11.9 1 9.8 6.9 1.9 2 0 0 2 2 2 0 Ring finger domain RRM_1 PF00076.22 KFM23124.1 - 5.1e-18 64.6 0.0 5.3e-09 35.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 KFM23124.1 - 3.5e-09 36.7 0.2 4.1e-08 33.3 0.2 2.3 2 0 0 2 2 2 1 RRM-like domain RRM_5 PF13893.6 KFM23124.1 - 4.4e-06 26.3 0.0 5e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 KFM23124.1 - 0.0053 16.7 0.1 0.7 9.9 0.0 2.6 2 1 0 2 2 2 1 RL domain Polyketide_cyc2 PF10604.9 KFM23125.1 - 1.7e-09 38.1 0.0 2.3e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 KFM23125.1 - 2.7e-06 27.6 0.0 4.5e-06 26.9 0.0 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport zf-C3HC4_4 PF15227.6 KFM23126.1 - 6.2e-08 32.7 3.3 6.2e-08 32.7 3.3 2.7 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KFM23126.1 - 1.8e-07 31.1 4.6 1.8e-07 31.1 4.6 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFM23126.1 - 5.7e-07 29.3 7.9 1.1e-06 28.4 2.5 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFM23126.1 - 1e-06 28.5 2.1 1e-06 28.5 2.1 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM23126.1 - 4e-05 23.5 2.6 0.00011 22.1 2.7 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KFM23126.1 - 0.00018 21.8 6.6 0.00018 21.8 6.6 2.4 2 1 0 2 2 2 1 Ring finger domain SPX PF03105.19 KFM23126.1 - 0.00023 21.2 5.4 0.0069 16.3 0.6 2.4 2 1 0 2 2 2 2 SPX domain zf-C3HC4_3 PF13920.6 KFM23126.1 - 0.029 14.2 12.9 0.089 12.7 10.0 2.7 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 KFM23126.1 - 0.049 13.5 0.7 0.1 12.4 0.7 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF4607 PF15380.6 KFM23126.1 - 0.049 13.1 0.1 0.1 12.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4607) zf-RING_6 PF14835.6 KFM23126.1 - 0.12 12.3 3.2 0.3 11.0 3.2 1.7 1 1 0 1 1 1 0 zf-RING of BARD1-type protein NOB1_Zn_bind PF08772.11 KFM23126.1 - 0.12 12.6 1.7 2.6 8.3 0.0 2.4 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-RING_10 PF16685.5 KFM23126.1 - 3.3 7.9 8.3 0.52 10.5 2.5 2.5 3 0 0 3 3 3 0 zinc RING finger of MSL2 PQ-loop PF04193.14 KFM23128.1 - 5.4e-08 32.5 0.9 7.5e-08 32.0 0.9 1.2 1 0 0 1 1 1 1 PQ loop repeat ER_lumen_recept PF00810.18 KFM23128.1 - 0.00067 20.5 0.1 0.00099 20.0 0.1 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor DUF4203 PF13886.6 KFM23128.1 - 0.0074 16.0 1.4 0.0096 15.6 1.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) S6PP PF05116.13 KFM23129.1 - 5.5e-07 29.4 0.1 7.1e-05 22.4 0.0 2.9 3 0 0 3 3 3 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.12 KFM23129.1 - 2.3e-05 24.2 0.2 0.0073 16.1 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFM23129.1 - 1.5 9.2 4.3 26 5.2 0.1 3.3 3 1 0 3 3 3 0 haloacid dehalogenase-like hydrolase YTH PF04146.15 KFM23130.1 - 2.1e-09 37.5 0.0 3.6e-08 33.5 0.0 2.2 1 1 0 1 1 1 1 YT521-B-like domain APG12 PF04110.13 KFM23131.1 - 1.6e-17 63.7 0.0 1.7e-17 63.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 HA2 PF04408.23 KFM23132.1 - 3.1e-21 75.7 0.0 3.1e-21 75.7 0.0 2.8 2 1 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KFM23132.1 - 1.1e-19 70.6 0.0 2.5e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KFM23132.1 - 7.6e-15 55.2 0.0 1.6e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KFM23132.1 - 0.00043 20.6 0.0 0.0025 18.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFM23132.1 - 0.0016 18.2 0.0 0.006 16.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 KFM23132.1 - 0.0017 18.2 0.0 0.0072 16.1 0.1 2.0 2 1 0 2 2 2 1 DEAD/DEAH box helicase T2SSE PF00437.20 KFM23132.1 - 0.0047 16.0 0.0 0.01 14.9 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 KFM23132.1 - 0.044 14.1 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFM23132.1 - 0.11 13.0 0.0 0.35 11.4 0.0 1.8 1 0 0 1 1 1 0 ABC transporter ATPase PF06745.13 KFM23132.1 - 0.12 11.7 0.1 0.24 10.7 0.1 1.4 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.6 KFM23132.1 - 0.6 10.6 0.0 0.6 10.6 0.0 2.6 2 1 0 2 2 1 0 AAA domain Longin PF13774.6 KFM23133.1 - 2.1e-19 69.3 0.0 3.1e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 KFM23133.1 - 3.8e-16 58.7 0.7 5.3e-16 58.2 0.7 1.2 1 0 0 1 1 1 1 Synaptobrevin Cpn60_TCP1 PF00118.24 KFM23134.1 - 3.2e-151 504.3 0.3 5.5e-151 503.5 0.1 1.5 2 0 0 2 2 2 1 TCP-1/cpn60 chaperonin family ALAD PF00490.21 KFM23134.1 - 1.7e-130 434.9 0.0 2.5e-130 434.3 0.0 1.3 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase ATP-synt_ab PF00006.25 KFM23134.1 - 8.6e-49 166.1 1.0 8e-34 117.2 0.2 2.5 1 1 1 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KFM23134.1 - 1.1e-19 70.7 2.1 2.7e-19 69.4 2.1 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain NB-ARC PF00931.22 KFM23134.1 - 0.039 13.1 0.1 0.075 12.2 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 KFM23134.1 - 0.069 13.5 0.9 0.58 10.5 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain NACHT PF05729.12 KFM23134.1 - 0.091 12.7 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain RsgA_GTPase PF03193.16 KFM23134.1 - 0.12 12.3 0.1 0.29 11.0 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase ABC_tran PF00005.27 KFM23134.1 - 0.19 12.3 0.0 0.83 10.2 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Usp PF00582.26 KFM23136.1 - 1.6e-10 41.7 4.1 0.00035 21.1 0.8 3.3 3 0 0 3 3 3 2 Universal stress protein family Cellulase PF00150.18 KFM23138.1 - 1.4e-12 47.7 0.0 2e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) EGF_3 PF12947.7 KFM23138.1 - 1.3e-05 25.3 6.1 3.9e-05 23.8 6.1 1.9 1 0 0 1 1 1 1 EGF domain PAN_1 PF00024.26 KFM23138.1 - 0.00035 20.5 4.6 0.00086 19.2 4.6 1.6 1 0 0 1 1 1 1 PAN domain EGF_CA PF07645.15 KFM23138.1 - 0.00068 19.8 4.9 0.0026 17.9 4.9 2.1 1 0 0 1 1 1 1 Calcium-binding EGF domain PAN_4 PF14295.6 KFM23138.1 - 0.002 18.0 4.7 0.0085 16.0 2.9 2.8 2 1 0 2 2 2 1 PAN domain Glyco_hydro_42 PF02449.15 KFM23138.1 - 0.0026 17.2 0.0 0.0044 16.4 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase EGF PF00008.27 KFM23138.1 - 0.5 10.7 3.7 1.6 9.1 3.7 1.9 1 0 0 1 1 1 0 EGF-like domain CN_hydrolase PF00795.22 KFM23139.1 - 9.6e-56 189.0 0.0 1.1e-55 188.8 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase RTP1_C2 PF10304.9 KFM23140.1 - 0.083 12.6 0.1 0.2 11.4 0.1 1.7 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 2 AP2 PF00847.20 KFM23141.1 - 3.3e-15 56.0 1.9 1.7e-07 31.3 0.3 2.5 2 1 0 2 2 2 2 AP2 domain Amidohydro_2 PF04909.14 KFM23141.1 - 0.07 12.9 0.3 0.13 12.0 0.3 1.4 1 0 0 1 1 1 0 Amidohydrolase Ribosomal_S27e PF01667.17 KFM23143.1 - 9.5e-27 92.5 6.4 1.6e-26 91.7 6.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S27 LRR_8 PF13855.6 KFM23143.1 - 7.8e-26 89.6 40.3 6.7e-09 35.4 10.8 4.0 1 1 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 KFM23143.1 - 9e-18 64.1 19.3 1.3e-06 28.6 0.3 5.3 2 2 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM23143.1 - 1.2e-08 34.4 12.3 0.69 10.7 0.0 7.4 7 0 0 7 7 7 3 Leucine Rich Repeat LRR_9 PF14580.6 KFM23143.1 - 3e-05 23.6 5.1 0.046 13.2 1.0 2.4 1 1 2 3 3 3 3 Leucine-rich repeat HTH_15 PF12324.8 KFM23143.1 - 0.037 14.0 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase LRR_6 PF13516.6 KFM23143.1 - 0.58 10.4 15.9 8.2 6.8 0.1 5.5 6 0 0 6 6 6 0 Leucine Rich repeat Peptidase_C65 PF10275.9 KFM23144.1 - 4e-55 186.9 0.0 1.2e-27 96.9 0.0 2.6 2 1 0 2 2 2 2 Peptidase C65 Otubain DNA_methylase PF00145.17 KFM23145.1 - 1.7e-24 86.8 0.0 2e-20 73.4 0.0 3.3 2 1 1 3 3 3 2 C-5 cytosine-specific DNA methylase PWWP PF00855.17 KFM23145.1 - 0.0014 19.0 0.0 0.0033 17.8 0.0 1.6 1 0 0 1 1 1 1 PWWP domain LBR_tudor PF09465.10 KFM23145.1 - 0.12 12.2 0.2 0.24 11.2 0.2 1.4 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain TUDOR_5 PF18359.1 KFM23145.1 - 0.23 11.2 0.1 0.61 9.8 0.0 1.7 2 0 0 2 2 2 0 Histone methyltransferase Tudor domain 1 zf-NF-X1 PF01422.17 KFM23146.1 - 0.00011 22.2 11.0 0.00011 22.2 11.0 7.2 8 0 0 8 8 8 4 NF-X1 type zinc finger Peptidase_M16 PF00675.20 KFM23147.1 - 1.8e-50 170.8 0.0 2.6e-50 170.3 0.0 1.2 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KFM23147.1 - 9.6e-37 126.8 0.0 8.3e-36 123.7 0.0 2.4 3 0 0 3 3 3 1 Peptidase M16 inactive domain Hydrolase_4 PF12146.8 KFM23148.1 - 1.3e-44 152.3 0.0 3.9e-44 150.7 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFM23148.1 - 7.2e-11 43.1 0.5 1.1e-10 42.6 0.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFM23148.1 - 5.5e-07 29.5 0.2 2e-06 27.6 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KFM23148.1 - 1.4e-05 24.9 0.0 2.3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 KFM23148.1 - 0.00021 20.8 0.0 0.19 11.2 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KFM23148.1 - 0.00043 20.2 0.4 0.14 12.0 0.0 2.6 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 KFM23148.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Pex2_Pex12 PF04757.14 KFM23149.1 - 5.5e-25 88.3 0.0 2.2e-24 86.3 0.0 1.8 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.6 KFM23149.1 - 6.3e-10 39.2 8.5 1.3e-09 38.2 8.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KFM23149.1 - 1.8e-09 37.3 8.8 2.9e-09 36.7 8.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFM23149.1 - 1.1e-08 34.7 7.7 2.5e-08 33.6 7.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM23149.1 - 3.9e-08 33.0 6.5 6.7e-08 32.3 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFM23149.1 - 1.9e-06 27.6 8.9 4e-06 26.6 8.9 1.5 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KFM23149.1 - 4.7e-06 26.5 1.5 4.7e-06 26.5 1.5 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFM23149.1 - 1.4e-05 25.0 6.8 7.3e-05 22.7 7.1 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 KFM23149.1 - 8e-05 22.9 13.0 0.00077 19.7 13.2 2.2 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KFM23149.1 - 0.002 18.3 7.5 0.002 18.3 7.5 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 KFM23149.1 - 0.5 10.5 6.5 0.89 9.7 6.5 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 TsaE PF02367.17 KFM23150.1 - 3.7e-25 88.3 0.0 4.4e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 KFM23150.1 - 0.025 15.0 0.0 0.028 14.8 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 KFM23150.1 - 0.032 14.6 0.0 0.045 14.1 0.0 1.2 1 0 0 1 1 1 0 RNA helicase KAP_NTPase PF07693.14 KFM23150.1 - 0.041 13.1 0.0 0.041 13.1 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain AAA_22 PF13401.6 KFM23150.1 - 0.11 12.8 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KFM23150.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF815 PF05673.13 KFM23150.1 - 0.23 10.6 0.0 0.57 9.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Pkinase PF00069.25 KFM23151.1 - 8.6e-16 58.1 0.0 2e-15 56.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KFM23151.1 - 2.1e-07 30.1 0.0 3e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KFM23151.1 - 0.00013 21.4 0.0 0.00019 20.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFM23151.1 - 0.1 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RCC1 PF00415.18 KFM23152.1 - 1.1e-68 227.6 34.6 6.4e-14 52.3 1.2 7.8 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFM23152.1 - 1.7e-41 139.2 41.3 5.6e-08 32.4 0.5 8.6 9 0 0 9 9 9 7 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 KFM23152.1 - 0.04 13.6 0.1 38 3.9 0.0 3.8 4 0 0 4 4 4 0 TUP1-like enhancer of split GAD-like PF08887.11 KFM23152.1 - 0.053 13.3 1.5 49 3.8 0.0 3.9 4 0 0 4 4 4 0 GAD-like domain NHL PF01436.21 KFM23152.1 - 0.14 12.2 0.2 2.3e+02 2.1 0.0 4.5 5 0 0 5 5 5 0 NHL repeat Kelch_5 PF13854.6 KFM23152.1 - 0.37 10.8 2.0 8.7 6.5 0.1 3.3 3 0 0 3 3 3 0 Kelch motif ANAPC4_WD40 PF12894.7 KFM23153.1 - 1.8e-18 66.6 0.2 4e-18 65.5 0.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain ANAPC4 PF12896.7 KFM23153.1 - 3e-18 66.0 0.2 4.6e-18 65.4 0.2 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 WD40 PF00400.32 KFM23153.1 - 0.07 14.0 0.9 0.38 11.7 0.0 2.7 3 0 0 3 3 3 0 WD domain, G-beta repeat Mg_trans_NIPA PF05653.14 KFM23155.1 - 5.5e-13 48.7 6.4 5.5e-13 48.7 6.4 1.6 2 0 0 2 2 2 1 Magnesium transporter NIPA EamA PF00892.20 KFM23155.1 - 0.01 16.0 0.6 0.01 16.0 0.6 3.5 3 1 1 4 4 4 0 EamA-like transporter family AAA PF00004.29 KFM23156.1 - 1.7e-38 132.0 0.0 3.5e-38 131.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFM23156.1 - 4.2e-08 32.9 0.5 1.5e-07 31.1 0.5 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KFM23156.1 - 1.4e-05 25.2 0.0 7.2e-05 22.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KFM23156.1 - 0.00033 20.8 0.0 0.00072 19.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KFM23156.1 - 0.0015 18.3 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.12 KFM23156.1 - 0.0059 16.4 0.0 0.016 15.0 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 KFM23156.1 - 0.0068 15.8 0.1 0.013 14.9 0.1 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 KFM23156.1 - 0.016 14.4 0.1 0.027 13.7 0.1 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_33 PF13671.6 KFM23156.1 - 0.017 15.2 0.0 0.048 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KFM23156.1 - 0.078 12.4 0.4 0.38 10.2 0.2 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_28 PF13521.6 KFM23156.1 - 0.15 12.3 0.8 0.46 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KFM23156.1 - 0.19 12.0 1.2 3.5 7.9 0.3 2.5 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KFM23156.1 - 0.21 12.0 3.9 0.68 10.3 0.5 3.0 2 1 0 2 2 2 0 AAA ATPase domain SNAPc_SNAP43 PF09808.9 KFM23157.1 - 1.5e-11 44.6 0.0 3.1e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 Dimerisation PF08100.11 KFM23157.1 - 0.11 12.6 0.1 0.33 11.0 0.0 1.9 2 0 0 2 2 2 0 Dimerisation domain LRR_6 PF13516.6 KFM23158.1 - 2.3e-56 183.1 37.0 2e-06 27.4 0.2 13.6 14 0 0 14 14 14 12 Leucine Rich repeat LRR_1 PF00560.33 KFM23158.1 - 5.5e-12 44.5 0.0 11 7.0 0.0 9.3 11 0 0 11 11 11 2 Leucine Rich Repeat LRR_4 PF12799.7 KFM23158.1 - 1.1e-11 44.8 14.1 0.0044 17.4 0.0 6.9 3 3 5 9 9 9 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFM23158.1 - 1.7e-07 30.9 19.4 0.081 12.7 2.5 8.2 3 3 3 6 6 6 3 Leucine rich repeat UPF0262 PF06793.12 KFM23158.1 - 0.073 13.2 0.2 8.4 6.5 0.0 3.6 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0262) LRR_2 PF07723.13 KFM23158.1 - 0.13 13.0 0.0 1.7e+02 3.1 0.0 4.8 6 0 0 6 6 6 0 Leucine Rich Repeat HTH_3 PF01381.22 KFM23158.1 - 0.42 10.7 1.6 2 8.5 0.1 2.8 3 0 0 3 3 3 0 Helix-turn-helix FAM25 PF15825.5 KFM23158.1 - 0.93 9.9 4.7 3.2 8.1 0.0 3.5 3 0 0 3 3 3 0 FAM25 family 5_3_exonuc_N PF02739.16 KFM23159.1 - 9.6e-38 129.6 0.0 1.4e-37 129.1 0.0 1.2 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 KFM23159.1 - 1.7e-18 67.0 0.0 2.8e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH PF00633.23 KFM23159.1 - 0.24 11.4 0.9 37 4.4 0.0 3.1 3 0 0 3 3 3 0 Helix-hairpin-helix motif Gp_dh_C PF02800.20 KFM23160.1 - 6.4e-71 237.1 0.2 1.6e-70 235.8 0.0 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KFM23160.1 - 5.8e-33 113.3 0.5 1.2e-32 112.2 0.1 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Peptidase_S8 PF00082.22 KFM23160.1 - 2.1e-22 79.8 11.1 2.1e-22 79.8 11.1 1.8 2 0 0 2 2 2 1 Subtilase family 2-Hacid_dh_C PF02826.19 KFM23160.1 - 0.0014 18.0 0.1 0.0026 17.1 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DapB_N PF01113.20 KFM23160.1 - 0.016 15.3 0.0 0.04 14.0 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus TFIIS_M PF07500.14 KFM23162.1 - 2.7e-24 85.8 0.0 5.4e-24 84.8 0.0 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain Ribul_P_3_epim PF00834.19 KFM23164.1 - 7.1e-71 237.7 0.0 1.4e-70 236.7 0.0 1.4 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.24 KFM23164.1 - 0.019 14.5 0.1 0.041 13.5 0.0 1.6 2 0 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family ThiG PF05690.14 KFM23164.1 - 0.044 13.1 1.0 0.064 12.6 1.0 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG Radical_SAM PF04055.21 KFM23164.1 - 0.047 14.1 0.0 0.19 12.1 0.0 1.9 2 1 1 3 3 3 0 Radical SAM superfamily Aa_trans PF01490.18 KFM23165.1 - 1.4e-40 139.2 20.4 1.8e-40 138.9 20.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ABC1 PF03109.16 KFM23166.1 - 3.2e-23 82.2 0.0 6.6e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 KFM23166.1 - 9.4e-05 22.4 11.3 0.00021 21.3 0.5 3.3 3 1 1 4 4 4 2 Phosphotransferase enzyme family Pkinase PF00069.25 KFM23166.1 - 0.096 12.0 0.0 0.8 9.0 0.0 2.3 3 0 0 3 3 3 0 Protein kinase domain DUF3581 PF12119.8 KFM23167.1 - 0.077 12.4 0.1 0.09 12.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3581) IF4E PF01652.18 KFM23168.1 - 6.7e-53 178.7 0.0 7.8e-53 178.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Erg28 PF03694.13 KFM23169.1 - 9e-27 93.6 0.1 1.2e-26 93.2 0.1 1.2 1 0 0 1 1 1 1 Erg28 like protein Ribosomal_L14e PF01929.17 KFM23171.1 - 3.5e-23 81.9 2.9 4.8e-23 81.4 2.7 1.3 1 1 0 1 1 1 1 Ribosomal protein L14 DUF647 PF04884.14 KFM23172.1 - 1e-39 136.6 1.9 3.1e-37 128.5 1.9 2.1 1 1 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis TPH PF13868.6 KFM23174.1 - 1.1e-06 27.5 87.7 0.00015 20.4 18.6 3.0 1 1 2 3 3 3 3 Trichohyalin-plectin-homology domain TFIIA PF03153.13 KFM23174.1 - 5 7.0 24.3 6.6 6.6 24.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SNARE PF05739.19 KFM23175.1 - 5.9e-06 26.2 0.0 6.6e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 SNARE domain Synaptobrevin PF00957.21 KFM23175.1 - 0.01 15.6 0.4 0.013 15.3 0.4 1.1 1 0 0 1 1 1 0 Synaptobrevin Use1 PF09753.9 KFM23175.1 - 0.013 15.2 0.1 0.015 15.1 0.1 1.0 1 0 0 1 1 1 0 Membrane fusion protein Use1 Myb_DNA-binding PF00249.31 KFM23176.1 - 2e-22 79.1 5.3 7.2e-12 45.3 1.3 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFM23176.1 - 3.2e-21 75.3 2.7 6.2e-13 48.8 2.2 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_Cef PF11831.8 KFM23176.1 - 1.2e-10 41.4 11.4 2.7e-10 40.2 0.5 4.1 2 1 1 3 3 3 2 pre-mRNA splicing factor component Rap1_C PF11626.8 KFM23176.1 - 0.012 15.7 0.0 0.86 9.7 0.1 2.6 2 1 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain EphA2_TM PF14575.6 KFM23179.1 - 0.094 13.6 0.1 0.15 12.9 0.1 1.4 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CHRD PF07452.12 KFM23180.1 - 1.8e-31 109.5 0.1 8.6e-23 81.5 0.1 2.3 2 0 0 2 2 2 2 CHRD domain FSAP_sig_propep PF03032.15 KFM23180.1 - 0.027 14.5 0.0 0.06 13.4 0.0 1.6 1 0 0 1 1 1 0 Frog skin active peptide family signal and propeptide CHRD PF07452.12 KFM23181.1 - 2.9e-16 60.5 0.1 3.9e-16 60.0 0.1 1.2 1 0 0 1 1 1 1 CHRD domain VIT1 PF01988.19 KFM23182.1 - 5.8e-55 186.5 7.5 6.9e-55 186.2 7.5 1.1 1 0 0 1 1 1 1 VIT family SBP56 PF05694.11 KFM23183.1 - 6.9e-184 611.9 0.0 6.3e-183 608.7 0.0 1.9 1 1 0 1 1 1 1 56kDa selenium binding protein (SBP56) Lactonase PF10282.9 KFM23183.1 - 0.011 15.0 0.0 0.062 12.6 0.0 1.9 1 1 1 2 2 2 0 Lactonase, 7-bladed beta-propeller Ribosomal_L27A PF00828.19 KFM23184.1 - 1.1e-16 61.7 0.0 1.2e-16 61.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A MRP-S34 PF16053.5 KFM23185.1 - 3e-08 33.4 0.0 3.4e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S34 RQC PF09382.10 KFM23185.1 - 0.11 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 RQC domain PCRF PF03462.18 KFM23188.1 - 3.8e-38 131.3 5.7 2.1e-26 93.0 0.0 2.4 2 1 1 3 3 3 2 PCRF domain RF-1 PF00472.20 KFM23188.1 - 3.2e-31 107.6 0.5 6.5e-31 106.7 0.5 1.4 1 0 0 1 1 1 1 RF-1 domain TMEM208_SND2 PF05620.11 KFM23189.1 - 8.6e-43 146.0 0.3 9.9e-43 145.8 0.3 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 HXXEE PF13787.6 KFM23189.1 - 0.18 12.6 4.1 8.9 7.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function with HXXEE motif Oxysterol_BP PF01237.18 KFM23190.1 - 5e-90 302.0 0.0 7.1e-90 301.5 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein CFTR_R PF14396.6 KFM23190.1 - 0.21 11.1 0.0 0.75 9.3 0.0 1.7 2 0 0 2 2 2 0 Cystic fibrosis TM conductance regulator (CFTR), regulator domain Pkinase PF00069.25 KFM23191.1 - 1.4e-30 106.5 0.0 5e-25 88.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFM23191.1 - 6.5e-29 101.0 0.0 1.1e-25 90.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFM23191.1 - 6.9e-06 25.1 0.0 1.1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Oxysterol_BP PF01237.18 KFM23192.1 - 2.1e-108 362.5 0.0 5.2e-108 361.2 0.0 1.6 1 1 0 1 1 1 1 Oxysterol-binding protein PH_11 PF15413.6 KFM23192.1 - 9.9e-05 22.7 0.0 0.00039 20.8 0.0 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KFM23192.1 - 0.0004 20.6 0.2 0.042 14.1 0.0 2.9 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.29 KFM23192.1 - 0.00079 19.9 0.0 0.0035 17.8 0.0 2.1 1 1 0 1 1 1 1 PH domain MetOD2 PF18548.1 KFM23192.1 - 0.037 14.1 0.3 0.074 13.2 0.3 1.4 1 0 0 1 1 1 0 Metanogen output domain 2 Torus PF16131.5 KFM23193.1 - 2e-29 102.5 0.4 3.5e-29 101.7 0.4 1.4 1 0 0 1 1 1 1 Torus domain RRM_1 PF00076.22 KFM23193.1 - 0.00099 18.9 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 KFM23193.1 - 0.0011 19.0 4.0 0.0021 18.0 4.0 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KFM23193.1 - 0.016 15.1 6.8 0.035 14.0 6.8 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) B3 PF02362.21 KFM23194.1 - 0.0016 18.2 0.0 0.0028 17.5 0.0 1.4 1 0 0 1 1 1 1 B3 DNA binding domain Nuc_sug_transp PF04142.15 KFM23195.1 - 6.2e-31 107.7 0.0 1.5e-30 106.5 0.0 1.4 1 1 0 1 1 1 1 Nucleotide-sugar transporter DSPc PF00782.20 KFM23195.1 - 1.7e-18 66.7 0.0 2.6e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain HAD_2 PF13419.6 KFM23195.1 - 2.4e-14 53.8 0.0 3.4e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFM23195.1 - 1.9e-10 41.4 0.5 4e-09 37.1 0.2 2.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFM23195.1 - 6.3e-05 23.0 0.1 6.3e-05 23.0 0.1 2.4 3 0 0 3 3 3 1 HAD-hyrolase-like UAA PF08449.11 KFM23195.1 - 0.00016 21.0 0.0 0.00024 20.4 0.0 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KFM23195.1 - 0.00041 20.5 3.8 0.00041 20.5 3.8 1.9 2 0 0 2 2 2 1 EamA-like transporter family DUF2605 PF10792.9 KFM23196.1 - 0.4 10.6 3.6 1.2 9.1 3.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2605) AMP-binding PF00501.28 KFM23197.1 - 1.6e-78 264.2 0.0 2.2e-78 263.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme hnRNP_Q_AcD PF18360.1 KFM23197.1 - 1.4e-17 63.4 0.0 1.7e-08 34.3 0.0 2.4 2 0 0 2 2 2 2 Heterogeneous nuclear ribonucleoprotein Q acidic domain DEAD PF00270.29 KFM23198.1 - 1.2e-47 162.0 0.0 2.3e-47 161.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM23198.1 - 1e-23 83.8 0.0 3e-23 82.3 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 KFM23198.1 - 2.1e-08 34.3 4.9 4.3e-08 33.3 4.9 1.5 1 0 0 1 1 1 1 DBP10CT (NUC160) domain ResIII PF04851.15 KFM23198.1 - 2.8e-05 24.2 0.0 5.7e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PIN_6 PF17146.4 KFM23199.1 - 3.1e-24 85.3 0.6 6.7e-24 84.2 0.6 1.6 1 0 0 1 1 1 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 KFM23199.1 - 1.4e-19 70.0 0.2 2.2e-19 69.4 0.2 1.3 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like RPE65 PF03055.15 KFM23200.1 - 1.4e-108 364.1 0.0 1.6e-108 363.9 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Redoxin PF08534.10 KFM23201.1 - 3.3e-26 91.8 0.0 4.2e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KFM23201.1 - 2.2e-12 47.0 0.0 3.6e-12 46.3 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family AhpC-TSA_2 PF13911.6 KFM23201.1 - 0.059 13.5 0.0 0.078 13.1 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme Meth_synt_2 PF01717.18 KFM23202.1 - 9e-138 459.0 0.0 7.8e-136 452.6 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KFM23202.1 - 2e-91 306.7 0.0 5.3e-83 279.1 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain Guanylate_kin PF00625.21 KFM23203.1 - 9.8e-48 162.2 0.0 1.4e-47 161.7 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 KFM23203.1 - 0.00018 21.9 0.7 0.0026 18.1 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 KFM23203.1 - 0.0029 17.5 0.0 0.0049 16.8 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase adh_short PF00106.25 KFM23203.1 - 0.0067 15.9 0.1 0.013 14.9 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase MMR_HSR1 PF01926.23 KFM23203.1 - 0.02 14.9 0.0 0.031 14.4 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 KFM23203.1 - 0.042 14.0 0.2 0.26 11.4 0.2 2.3 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 KFM23203.1 - 0.13 11.5 0.0 0.19 11.0 0.0 1.1 1 0 0 1 1 1 0 Septin AAA_22 PF13401.6 KFM23203.1 - 0.14 12.4 0.0 0.42 10.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KFM23203.1 - 0.15 12.5 0.7 0.54 10.7 0.3 2.0 3 0 0 3 3 2 0 AAA domain Roc PF08477.13 KFM23203.1 - 0.2 11.9 0.1 0.3 11.3 0.1 1.2 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 KFM23203.1 - 0.2 11.2 0.0 0.32 10.6 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain MobB PF03205.14 KFM23203.1 - 0.24 11.3 0.1 0.83 9.5 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 KFM23203.1 - 0.25 11.2 0.0 0.39 10.6 0.0 1.2 1 0 0 1 1 1 0 NTPase AAA_7 PF12775.7 KFM23203.1 - 0.29 10.6 0.0 0.48 9.9 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region T3SS_needle_E PF08988.10 KFM23203.1 - 3 8.1 4.8 1.4 9.1 0.9 2.3 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle UPF0220 PF05255.11 KFM23204.1 - 1.8e-22 79.6 0.1 2.2e-22 79.3 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) WD40 PF00400.32 KFM23205.1 - 7.8e-13 48.7 5.9 6e-06 26.9 1.6 4.7 4 1 1 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM23205.1 - 8.7e-11 42.0 0.0 4.7e-06 26.8 0.0 3.4 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain CARDB PF07705.11 KFM23206.1 - 0.1 12.8 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 CARDB PDCD2_C PF04194.13 KFM23208.1 - 4.6e-15 56.1 0.5 1.6e-12 47.8 0.0 2.4 1 1 1 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain FH2 PF02181.23 KFM23211.1 - 8.5e-51 173.2 0.0 1.7e-28 99.8 0.0 2.1 2 0 0 2 2 2 2 Formin Homology 2 Domain PTEN_C2 PF10409.9 KFM23211.1 - 0.087 12.6 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein CWC25 PF12542.8 KFM23213.1 - 2.1e-12 47.8 0.0 2.1e-12 47.8 0.0 3.3 3 1 0 3 3 3 1 Pre-mRNA splicing factor Cir_N PF10197.9 KFM23213.1 - 1.1e-10 41.5 7.9 1.1e-10 41.5 7.9 3.3 3 1 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR Taxilin PF09728.9 KFM23213.1 - 0.94 8.6 11.7 0.59 9.3 2.5 2.3 2 0 0 2 2 2 0 Myosin-like coiled-coil protein LSM PF01423.22 KFM23214.1 - 2.5e-20 71.9 0.2 2.9e-20 71.7 0.2 1.1 1 0 0 1 1 1 1 LSM domain CHCH PF06747.13 KFM23215.1 - 3.3e-05 23.9 6.8 8.4e-05 22.6 6.9 1.6 1 1 1 2 2 2 2 CHCH domain CX9C PF16860.5 KFM23215.1 - 0.0025 17.8 2.4 0.0036 17.3 2.4 1.2 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, MTCP1 PF08991.10 KFM23215.1 - 0.01 16.0 1.0 0.014 15.6 1.0 1.2 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type Cmc1 PF08583.10 KFM23215.1 - 0.043 13.8 3.0 0.075 13.1 3.0 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF3128 PF11326.8 KFM23215.1 - 0.048 14.0 3.8 0.53 10.7 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) Colipase-like PF15083.6 KFM23215.1 - 0.069 13.3 0.3 0.081 13.1 0.3 1.1 1 0 0 1 1 1 0 Colipase-like ATP-synt_Eps PF04627.13 KFM23216.1 - 1.3e-15 57.1 1.2 1.6e-15 56.8 1.2 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain SAND PF01342.21 KFM23217.1 - 8.2e-09 35.1 0.2 1.6e-08 34.1 0.2 1.4 1 0 0 1 1 1 1 SAND domain zf-HC5HC2H PF13771.6 KFM23217.1 - 1.9e-05 24.9 0.0 4.2e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain Rootletin PF15035.6 KFM23217.1 - 0.28 11.2 7.3 0.46 10.5 7.3 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion RgpF PF05045.12 KFM23219.1 - 0.0011 17.9 0.0 0.0021 16.9 0.0 1.3 1 0 0 1 1 1 1 Rhamnan synthesis protein F Ribosomal_L11_N PF03946.14 KFM23220.1 - 1.7e-30 104.7 0.9 1.7e-30 104.7 0.9 1.9 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 KFM23220.1 - 1.7e-24 86.1 0.5 2.8e-24 85.4 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Mcl1_mid PF12341.8 KFM23222.1 - 8.5e-67 225.6 0.0 1.8e-65 221.2 0.0 2.5 3 0 0 3 3 3 1 Minichromosome loss protein, Mcl1, middle region ANAPC4_WD40 PF12894.7 KFM23222.1 - 6.9e-10 39.1 0.0 0.009 16.3 0.0 4.0 2 2 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFM23222.1 - 3.2e-09 37.3 0.8 0.59 11.1 0.0 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat RPOL_N PF14700.6 KFM23223.1 - 0.066 12.6 0.1 0.084 12.3 0.1 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal RRM_1 PF00076.22 KFM23225.1 - 2.1e-26 91.6 0.0 3.4e-13 49.2 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFM23225.1 - 0.0012 18.9 0.0 0.58 10.3 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif adh_short PF00106.25 KFM23226.1 - 1.2e-33 116.2 0.1 1.5e-33 115.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM23226.1 - 4.1e-30 105.1 0.1 5.7e-30 104.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM23226.1 - 2.6e-08 34.0 0.3 3.9e-08 33.4 0.3 1.3 1 0 0 1 1 1 1 KR domain FIST PF08495.10 KFM23226.1 - 0.11 12.5 0.3 0.21 11.6 0.3 1.6 1 1 0 1 1 1 0 FIST N domain Epimerase PF01370.21 KFM23226.1 - 0.12 11.8 0.0 1 8.8 0.1 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Helicase_C_4 PF13871.6 KFM23228.1 - 1.4e-105 352.8 0.2 2e-105 352.4 0.2 1.2 1 0 0 1 1 1 1 C-terminal domain on Strawberry notch homologue AAA_34 PF13872.6 KFM23228.1 - 5.1e-100 334.3 0.0 7.2e-100 333.8 0.0 1.2 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 UBA PF00627.31 KFM23228.1 - 6e-09 35.6 1.2 8.6e-08 31.9 0.1 2.8 2 0 0 2 2 2 1 UBA/TS-N domain Helicase_C PF00271.31 KFM23228.1 - 0.092 13.1 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 Helicase conserved C-terminal domain INCENP_ARK-bind PF03941.15 KFM23229.1 - 6.7e-07 29.2 5.0 5e-05 23.2 5.0 2.7 1 1 0 1 1 1 1 Inner centromere protein, ARK binding region DUF937 PF06078.11 KFM23231.1 - 0.1 13.2 3.9 0.1 13.2 2.0 1.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF937) DUF4164 PF13747.6 KFM23231.1 - 0.16 12.3 8.4 0.23 11.7 5.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Asparaginase_2 PF01112.18 KFM23232.1 - 5.1e-39 134.1 0.5 1.5e-38 132.6 0.5 1.6 1 1 0 1 1 1 1 Asparaginase EamA PF00892.20 KFM23233.1 - 2.4e-15 56.9 35.0 5.7e-10 39.5 14.6 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 KFM23233.1 - 0.0011 18.4 6.5 0.0012 18.3 5.5 1.3 1 1 0 1 1 1 1 Triose-phosphate Transporter family DUF4381 PF14316.6 KFM23233.1 - 0.096 12.9 0.3 0.096 12.9 0.3 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) Pyrophosphatase PF00719.19 KFM23234.1 - 7.1e-47 159.2 0.2 9e-47 158.9 0.2 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Pyrophosphatase PF00719.19 KFM23235.1 - 2e-42 144.7 0.1 4.2e-42 143.7 0.0 1.6 2 0 0 2 2 2 1 Inorganic pyrophosphatase CLZ PF16526.5 KFM23235.1 - 0.051 14.0 0.2 0.051 14.0 0.2 4.3 5 1 0 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4047 PF13256.6 KFM23235.1 - 0.1 12.8 0.3 0.25 11.5 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) D123 PF07065.14 KFM23236.1 - 3.2e-64 217.0 0.0 4.7e-64 216.5 0.0 1.4 1 1 0 1 1 1 1 D123 PIH1 PF08190.12 KFM23237.1 - 7.9e-16 58.0 0.0 3.6e-15 55.8 0.0 1.9 1 1 0 1 1 1 1 PIH1 N-terminal domain Ion_trans PF00520.31 KFM23237.1 - 7.5e-12 45.0 23.0 1.2e-11 44.4 23.0 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KFM23237.1 - 2.8e-11 43.2 4.6 2.8e-11 43.2 4.6 2.1 2 0 0 2 2 2 1 Ion channel cNMP_binding PF00027.29 KFM23237.1 - 0.043 13.9 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain Beach PF02138.18 KFM23238.1 - 6e-113 376.8 0.0 7.7e-113 376.5 0.0 1.1 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 KFM23238.1 - 4.7e-08 33.0 0.0 7.3e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 KFM23238.1 - 0.0018 19.1 0.1 13 6.8 0.0 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF1088 PF06469.11 KFM23238.1 - 0.0079 15.9 0.2 0.015 15.0 0.2 1.3 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1088) Laminin_G_3 PF13385.6 KFM23239.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Usp PF00582.26 KFM23240.1 - 1.5e-07 32.0 0.0 1.1e-06 29.3 0.0 2.0 1 1 0 1 1 1 1 Universal stress protein family Enkurin PF13864.6 KFM23241.1 - 0.0018 18.7 0.2 0.0024 18.2 0.2 1.6 1 1 0 1 1 1 1 Calmodulin-binding ABC_tran_CTD PF16326.5 KFM23241.1 - 0.0056 16.9 8.6 0.66 10.3 0.2 3.3 3 0 0 3 3 3 2 ABC transporter C-terminal domain T3SSipB PF16535.5 KFM23241.1 - 0.78 10.2 5.3 0.53 10.7 3.7 1.5 2 0 0 2 2 2 0 Type III cell invasion protein SipB SOAR PF16533.5 KFM23241.1 - 1.1 9.3 3.5 4.6 7.3 0.4 2.4 2 1 0 2 2 2 0 STIM1 Orai1-activating region HLH PF00010.26 KFM23241.1 - 1.4 9.0 5.2 0.82 9.7 3.2 1.6 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain DUF4140 PF13600.6 KFM23241.1 - 3.9 8.0 11.3 21 5.7 0.4 3.3 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) bZIP_2 PF07716.15 KFM23241.1 - 7.4 6.7 10.7 2 8.6 2.3 2.8 3 0 0 3 3 3 0 Basic region leucine zipper GRIP PF01465.20 KFM23242.1 - 1.1e-07 31.6 0.1 3.5e-07 30.0 0.1 1.9 1 1 0 1 1 1 1 GRIP domain TMF_TATA_bd PF12325.8 KFM23242.1 - 0.00036 20.7 5.4 0.00036 20.7 5.4 8.7 6 1 4 10 10 10 1 TATA element modulatory factor 1 TATA binding HALZ PF02183.18 KFM23242.1 - 0.18 12.1 16.0 1.4 9.2 0.0 6.3 5 1 0 5 5 5 0 Homeobox associated leucine zipper DUF2730 PF10805.8 KFM23242.1 - 0.54 10.4 2.6 4.9 7.3 0.0 3.9 5 0 0 5 5 5 0 Protein of unknown function (DUF2730) Peptidase_C54 PF03416.19 KFM23243.1 - 1.8e-74 250.6 0.0 2.3e-74 250.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 RYDR_ITPR PF01365.21 KFM23244.1 - 0.012 15.1 0.0 0.016 14.7 0.0 1.1 1 0 0 1 1 1 0 RIH domain PIF1 PF05970.14 KFM23245.1 - 1.2e-17 64.2 0.0 1.2e-16 60.9 0.0 1.9 1 1 1 2 2 2 1 PIF1-like helicase AAA_30 PF13604.6 KFM23245.1 - 6.8e-10 39.0 1.5 4.7e-08 33.0 0.7 2.2 1 1 1 2 2 2 1 AAA domain AAA_29 PF13555.6 KFM23245.1 - 0.00014 21.5 0.0 0.00027 20.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_19 PF13245.6 KFM23245.1 - 0.00024 21.4 0.0 0.0012 19.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KFM23245.1 - 0.0016 17.9 0.1 0.003 17.0 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KFM23245.1 - 0.0059 17.0 0.5 0.015 15.7 0.5 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 KFM23245.1 - 0.015 14.8 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 KFM23245.1 - 0.04 13.4 0.0 0.057 12.9 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.6 KFM23245.1 - 0.053 13.8 0.2 0.14 12.5 0.2 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFM23245.1 - 0.08 13.4 0.0 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter T2SSE PF00437.20 KFM23245.1 - 0.096 11.7 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 KFM23245.1 - 0.16 11.7 0.0 0.77 9.5 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein MCM PF00493.23 KFM23245.1 - 0.18 10.9 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain Iso_dh PF00180.20 KFM23246.1 - 9.7e-103 343.9 0.0 1.2e-102 343.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Cytochrom_C PF00034.21 KFM23247.1 - 6.5e-13 49.6 0.0 9.1e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KFM23247.1 - 1.4e-07 31.7 2.5 4.8e-07 30.0 2.5 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 KFM23247.1 - 0.0026 17.5 0.3 0.015 15.0 0.1 1.9 2 0 0 2 2 2 1 Cytochrome c-550 domain KxDL PF10241.9 KFM23248.1 - 0.073 13.3 2.7 0.13 12.6 0.5 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein ANAPC4_WD40 PF12894.7 KFM23249.1 - 0.00014 22.1 0.0 0.43 10.9 0.0 3.1 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFM23249.1 - 0.0015 19.3 0.1 7.6 7.6 0.0 4.2 4 0 0 4 4 4 1 WD domain, G-beta repeat Porin_3 PF01459.22 KFM23250.1 - 4.1e-36 124.8 0.0 4.8e-36 124.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin DapB_N PF01113.20 KFM23250.1 - 0.13 12.3 0.1 0.35 11.0 0.0 1.7 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Plasmod_MYXSPDY PF07981.11 KFM23250.1 - 0.74 9.9 2.5 85 3.4 0.0 3.3 3 0 0 3 3 3 0 Plasmodium repeat_MYXSPDY SNF2_N PF00176.23 KFM23251.1 - 1.9e-40 138.7 2.8 7.8e-24 84.0 0.3 2.3 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KFM23251.1 - 5.5e-20 71.8 0.0 1e-19 70.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KFM23251.1 - 2.5e-10 40.0 0.0 7.5e-10 38.4 0.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.24 KFM23251.1 - 2.3e-06 27.4 0.1 5.1e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.6 KFM23251.1 - 3.5e-06 27.4 0.0 1.2e-05 25.7 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) ResIII PF04851.15 KFM23251.1 - 0.00039 20.5 0.0 0.25 11.3 0.0 2.6 1 1 1 2 2 2 2 Type III restriction enzyme, res subunit tRNA-synt_2b PF00587.25 KFM23252.1 - 1.1e-33 116.8 0.0 1.7e-33 116.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KFM23252.1 - 8.8e-24 83.8 1.0 1.7e-23 82.9 1.0 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Lipoprotein_2 PF00921.17 KFM23252.1 - 0.0069 16.0 0.2 0.01 15.4 0.2 1.1 1 0 0 1 1 1 1 Borrelia lipoprotein CALCOCO1 PF07888.11 KFM23252.1 - 0.035 13.0 2.7 0.052 12.4 2.7 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like BicD PF09730.9 KFM23252.1 - 0.04 12.3 4.1 0.056 11.9 4.1 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D COX16 PF14138.6 KFM23254.1 - 1.2e-19 70.6 0.0 1.4e-19 70.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 AP2 PF00847.20 KFM23257.1 - 7.3e-18 64.5 22.3 3.9e-07 30.2 3.2 4.1 4 1 0 4 4 4 3 AP2 domain ANAPC4_WD40 PF12894.7 KFM23259.1 - 2.6e-05 24.4 0.1 0.027 14.8 0.1 4.1 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFM23259.1 - 0.005 17.7 3.2 10 7.2 0.0 5.2 6 0 0 6 6 6 1 WD domain, G-beta repeat Flagellar_rod PF05149.12 KFM23259.1 - 0.03 13.8 0.8 0.044 13.3 0.8 1.1 1 0 0 1 1 1 0 Paraflagellar rod protein Nbas_N PF15492.6 KFM23259.1 - 0.17 11.2 0.0 20 4.4 0.0 2.4 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal V_ATPase_I PF01496.19 KFM23260.1 - 1.1e-275 916.6 0.0 1.3e-275 916.5 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family ABC_tran_CTD PF16326.5 KFM23260.1 - 0.034 14.4 0.7 0.21 11.8 0.2 2.2 2 0 0 2 2 2 0 ABC transporter C-terminal domain HAP1_N PF04849.13 KFM23260.1 - 0.058 12.6 0.2 0.086 12.0 0.2 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region DHR10 PF18595.1 KFM23260.1 - 0.065 13.3 3.9 3.3 7.8 0.6 2.5 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain baeRF_family2 PF18844.1 KFM23260.1 - 0.086 12.9 4.3 0.1 12.7 2.7 1.9 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 2 CCDC154 PF15450.6 KFM23260.1 - 0.12 10.9 0.1 0.25 9.9 0.0 1.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 154 Cep57_MT_bd PF06657.13 KFM23260.1 - 0.2 12.1 0.5 0.59 10.6 0.1 1.9 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF2371 PF10177.9 KFM23260.1 - 0.41 10.8 0.9 1.5 9.0 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) Caveolin PF01146.17 KFM23260.1 - 1 9.3 3.6 3.2 7.7 3.6 1.8 1 0 0 1 1 1 0 Caveolin RRM_1 PF00076.22 KFM23261.1 - 1.3e-12 47.3 0.0 1.9e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFM23261.1 - 8e-05 22.7 0.0 0.0041 17.2 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif DUF1866 PF08952.11 KFM23261.1 - 0.03 14.1 0.0 0.043 13.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) Glyco_transf_8 PF01501.20 KFM23262.1 - 1.9e-08 34.2 0.1 3.8e-07 29.9 0.1 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 8 Chitin_synth_2 PF03142.15 KFM23262.1 - 0.18 10.4 0.0 0.24 10.0 0.0 1.1 1 0 0 1 1 1 0 Chitin synthase tRNA-synt_2c PF01411.19 KFM23263.1 - 2.6e-208 693.0 0.0 3.2e-208 692.7 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (A) DHHA1 PF02272.19 KFM23263.1 - 5e-17 62.6 2.1 1.3e-16 61.2 2.1 1.7 1 0 0 1 1 1 1 DHHA1 domain tRNA_SAD PF07973.14 KFM23263.1 - 1.3e-15 57.2 0.0 2.7e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain RNA_pol_Rpb6 PF01192.22 KFM23264.1 - 2.2e-16 59.5 0.1 2.9e-16 59.1 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb6 TTL PF03133.15 KFM23266.1 - 6.6e-41 140.4 0.0 6.3e-29 101.0 0.0 2.5 2 1 1 3 3 3 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KFM23266.1 - 1.5e-06 27.7 0.0 0.0027 17.0 0.0 2.8 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KFM23266.1 - 0.00056 19.3 0.0 0.096 11.9 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp TMF_TATA_bd PF12325.8 KFM23266.1 - 0.33 11.2 7.9 0.27 11.5 2.1 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding GlnD_UR_UTase PF08335.11 KFM23266.1 - 0.75 9.9 6.1 0.1 12.7 0.6 2.2 2 0 0 2 2 2 0 GlnD PII-uridylyltransferase Rad51 PF08423.11 KFM23268.1 - 8.1e-117 389.0 0.1 1.1e-116 388.6 0.1 1.2 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 KFM23268.1 - 9.5e-14 51.5 0.3 1.3e-13 51.1 0.3 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 KFM23268.1 - 4.3e-08 33.0 0.0 6.8e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KFM23268.1 - 2.3e-06 27.1 0.0 6.8e-06 25.6 0.0 1.9 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.6 KFM23268.1 - 1.9e-05 25.1 1.0 6e-05 23.6 1.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_24 PF13479.6 KFM23268.1 - 0.00012 21.9 0.0 0.00022 21.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_pol_A_CTD PF03118.15 KFM23268.1 - 0.027 14.2 0.9 0.055 13.2 0.4 1.7 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain HTH_36 PF13730.6 KFM23268.1 - 0.096 12.7 0.0 1.5 8.9 0.0 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain Peptidase_M24 PF00557.24 KFM23269.1 - 8.9e-40 136.6 0.1 1.2e-39 136.2 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 SRP-alpha_N PF04086.13 KFM23269.1 - 3.6 7.4 13.1 6.2 6.7 13.1 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal GBP PF02263.19 KFM23271.1 - 2.8e-31 108.8 0.0 4e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain RHD3 PF05879.12 KFM23271.1 - 0.028 12.6 0.0 0.034 12.3 0.0 1.1 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) Dynamin_N PF00350.23 KFM23271.1 - 0.08 13.0 0.0 0.22 11.6 0.0 1.6 2 0 0 2 2 2 0 Dynamin family DCP2 PF05026.13 KFM23271.1 - 0.18 12.2 0.0 0.45 10.9 0.0 1.6 1 0 0 1 1 1 0 Dcp2, box A domain MMR_HSR1 PF01926.23 KFM23271.1 - 0.22 11.6 0.0 0.37 10.9 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 KFM23271.1 - 1.2 9.5 6.0 2.1 8.7 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain FPL PF09758.9 KFM23272.1 - 1e-56 191.0 0.1 1.4e-56 190.6 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein RAI16-like PF10257.9 KFM23272.1 - 0.13 11.2 0.1 0.18 10.6 0.1 1.2 1 0 0 1 1 1 0 Retinoic acid induced 16-like protein DEAD PF00270.29 KFM23274.1 - 3.6e-44 150.6 0.1 5.3e-44 150.1 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM23274.1 - 6.1e-29 100.6 0.0 2.7e-28 98.5 0.0 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KFM23274.1 - 0.0034 16.6 0.0 0.006 15.8 0.0 1.4 1 1 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KFM23274.1 - 0.012 15.7 0.0 0.035 14.1 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit CMS1 PF14617.6 KFM23274.1 - 0.014 14.7 0.0 0.039 13.3 0.0 1.6 1 1 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit GTP_EFTU PF00009.27 KFM23275.1 - 9.8e-22 77.4 0.1 1.6e-21 76.8 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KFM23275.1 - 3.2e-07 30.6 0.4 8.2e-06 26.1 0.2 2.6 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 KFM23275.1 - 0.00018 21.8 0.2 0.00064 20.0 0.2 1.9 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KFM23275.1 - 0.0022 18.1 0.0 0.0048 17.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 KFM23275.1 - 0.011 15.5 0.1 2.9 7.6 0.0 3.6 2 2 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.17 KFM23275.1 - 0.097 12.8 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain PfkB PF00294.24 KFM23276.1 - 7.5e-27 94.4 0.1 1.1e-26 93.9 0.1 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase TPR_2 PF07719.17 KFM23277.1 - 1.4 9.2 3.7 10 6.5 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_16 PF13191.6 KFM23279.1 - 2.1e-11 44.5 0.6 9.6e-11 42.4 0.6 2.2 1 1 0 1 1 1 1 AAA ATPase domain Guanylate_cyc PF00211.20 KFM23279.1 - 2.1e-09 37.3 0.0 5.2e-07 29.5 0.0 2.2 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain NACHT PF05729.12 KFM23279.1 - 0.0096 15.9 1.5 0.038 13.9 0.3 2.2 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 KFM23279.1 - 0.043 14.1 0.0 0.64 10.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain CtaG_Cox11 PF04442.14 KFM23280.1 - 1.9e-34 118.9 0.1 7.5e-19 68.2 0.0 2.1 1 1 1 2 2 2 2 Cytochrome c oxidase assembly protein CtaG/Cox11 Rieske_2 PF13806.6 KFM23281.1 - 1.9e-15 56.6 0.0 3.2e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain GIT_CC PF16559.5 KFM23282.1 - 0.01 15.7 5.9 0.01 15.7 5.9 1.7 2 0 0 2 2 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor CENP-F_leu_zip PF10473.9 KFM23282.1 - 0.013 15.6 8.6 0.013 15.6 8.6 1.8 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LCD1 PF09798.9 KFM23282.1 - 0.03 12.9 1.5 0.036 12.6 1.5 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein CC2-LZ PF16516.5 KFM23282.1 - 0.048 14.0 7.7 0.27 11.6 7.2 2.3 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator bZIP_2 PF07716.15 KFM23282.1 - 0.092 12.8 18.5 0.53 10.4 2.8 3.6 3 1 1 4 4 4 0 Basic region leucine zipper YabA PF06156.13 KFM23282.1 - 0.15 12.7 11.2 0.15 12.7 5.1 2.8 1 1 2 3 3 3 0 Initiation control protein YabA bZIP_1 PF00170.21 KFM23282.1 - 0.21 11.7 9.2 0.77 9.9 2.1 3.4 3 1 1 4 4 4 0 bZIP transcription factor ATG16 PF08614.11 KFM23282.1 - 0.24 11.6 20.6 1.1 9.5 16.4 2.9 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF2730 PF10805.8 KFM23282.1 - 0.49 10.5 3.7 11 6.1 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) TMF_TATA_bd PF12325.8 KFM23282.1 - 0.5 10.6 14.6 2.2 8.5 5.9 2.9 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.11 KFM23282.1 - 0.57 9.0 8.6 0.97 8.2 8.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Golgin_A5 PF09787.9 KFM23282.1 - 0.91 8.9 13.9 0.57 9.6 10.1 1.9 1 1 0 2 2 2 0 Golgin subfamily A member 5 Fungal_TACC PF12709.7 KFM23282.1 - 1.3 9.5 7.2 6.9 7.2 3.6 3.0 2 1 2 4 4 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins UPF0242 PF06785.11 KFM23282.1 - 1.8 8.6 7.8 3.2 7.8 7.2 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PRKG1_interact PF15898.5 KFM23282.1 - 2.7 8.9 10.1 0.89 10.5 6.6 1.9 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain APG6_N PF17675.1 KFM23282.1 - 2.8 8.5 18.0 0.4 11.2 12.8 2.2 2 1 0 2 2 2 0 Apg6 coiled-coil region DivIC PF04977.15 KFM23282.1 - 3.1 7.6 12.9 1.3 8.8 4.5 3.0 3 0 0 3 3 3 0 Septum formation initiator LPP PF04728.13 KFM23282.1 - 4.2 7.8 9.7 2.7 8.5 3.7 3.0 1 1 2 3 3 3 0 Lipoprotein leucine-zipper ADIP PF11559.8 KFM23282.1 - 9.9 6.2 12.7 6.7 6.8 6.0 2.7 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding MMACHC PF16690.5 KFM23283.1 - 0.0049 16.5 0.0 0.034 13.8 0.0 2.1 1 1 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type C family Nop16 PF09420.10 KFM23285.1 - 7.7e-21 75.1 0.5 5.9e-15 55.9 0.0 2.1 1 1 1 2 2 2 2 Ribosome biogenesis protein Nop16 ORF_12_N PF18042.1 KFM23285.1 - 0.027 14.9 0.0 0.049 14.1 0.0 1.4 1 0 0 1 1 1 0 ORF 12 gene product N-terminal DAHP_synth_2 PF01474.16 KFM23286.1 - 1.4e-189 630.2 0.0 1.6e-189 630.0 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family DUF772 PF05598.11 KFM23286.1 - 0.051 13.6 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Transposase domain (DUF772) RRM_1 PF00076.22 KFM23288.1 - 3.1e-39 132.6 0.0 4.9e-16 58.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFM23288.1 - 8.4e-07 28.6 0.0 0.05 13.2 0.0 3.2 2 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFM23288.1 - 3.5e-05 23.8 0.0 0.3 11.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif DUF3906 PF13046.6 KFM23288.1 - 0.13 12.4 0.0 1.1 9.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3906) MMR_HSR1 PF01926.23 KFM23289.1 - 4.3e-08 33.2 0.0 6.2e-07 29.5 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 KFM23289.1 - 0.073 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 AIG1 family Rad4 PF03835.15 KFM23293.1 - 0.15 11.7 1.5 0.25 11.0 1.5 1.3 1 0 0 1 1 1 0 Rad4 transglutaminase-like domain EF_TS PF00889.19 KFM23294.1 - 2.3e-50 171.1 0.0 3.1e-50 170.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor TS Exostosin PF03016.15 KFM23296.1 - 4.9e-30 104.8 0.6 7.5e-30 104.2 0.0 1.5 2 0 0 2 2 2 1 Exostosin family EGF_2 PF07974.13 KFM23296.1 - 1.3e-06 28.7 59.1 0.0016 18.7 11.0 4.7 4 0 0 4 4 4 3 EGF-like domain hEGF PF12661.7 KFM23296.1 - 0.02 15.5 5.2 0.02 15.5 5.2 5.0 6 0 0 6 6 6 0 Human growth factor-like EGF Peptidase_M41 PF01434.18 KFM23297.1 - 2.8e-64 216.5 0.0 3.9e-64 216.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KFM23297.1 - 5.7e-44 149.8 0.0 1e-43 148.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFM23297.1 - 2.1e-15 56.2 1.5 3.7e-15 55.5 0.2 2.1 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 KFM23297.1 - 9.9e-05 22.4 0.0 0.0006 19.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFM23297.1 - 0.00068 20.1 0.3 0.019 15.3 0.1 2.8 1 1 1 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 KFM23297.1 - 0.003 16.8 0.1 0.006 15.8 0.1 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 KFM23297.1 - 0.004 17.4 0.1 0.094 13.0 0.1 2.3 1 1 0 2 2 2 1 AAA domain AAA_2 PF07724.14 KFM23297.1 - 0.0046 17.1 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KFM23297.1 - 0.0083 15.9 0.0 0.026 14.3 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 KFM23297.1 - 0.01 15.6 0.1 0.026 14.2 0.0 1.7 2 0 0 2 2 1 1 IstB-like ATP binding protein FtsH_ext PF06480.15 KFM23297.1 - 0.018 15.4 0.0 0.16 12.3 0.0 2.4 2 0 0 2 2 2 0 FtsH Extracellular AAA_28 PF13521.6 KFM23297.1 - 0.03 14.6 0.7 0.079 13.2 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KFM23297.1 - 0.044 13.9 0.1 0.12 12.6 0.1 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KFM23297.1 - 0.045 13.1 0.4 0.085 12.2 0.4 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KFM23297.1 - 0.074 12.6 2.7 0.99 8.9 0.5 2.7 2 1 0 3 3 3 0 AAA domain DUF3123 PF11321.8 KFM23297.1 - 0.081 13.6 2.5 0.21 12.3 2.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) AAA_7 PF12775.7 KFM23297.1 - 0.16 11.4 0.2 0.51 9.8 0.2 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region DUF3157 PF11355.8 KFM23297.1 - 0.22 11.1 0.0 0.63 9.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3157) AraC_binding_2 PF14525.6 KFM23297.1 - 0.29 10.8 2.7 0.3 10.7 0.8 2.0 2 0 0 2 2 2 0 AraC-binding-like domain WD40 PF00400.32 KFM23298.1 - 9e-24 83.3 10.4 2.1e-07 31.5 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat NLE PF08154.12 KFM23298.1 - 7.7e-21 74.4 0.1 1.1e-20 73.9 0.1 1.2 1 0 0 1 1 1 1 NLE (NUC135) domain ANAPC4_WD40 PF12894.7 KFM23298.1 - 6.9e-09 35.9 0.2 0.017 15.4 0.0 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain tRNA_edit PF04073.15 KFM23299.1 - 7.6e-05 22.8 0.0 0.00013 22.0 0.0 1.5 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain mTERF PF02536.14 KFM23300.1 - 1e-15 57.5 0.0 1.3e-07 30.8 0.0 2.5 2 1 0 2 2 2 2 mTERF RuvA_C PF07499.13 KFM23300.1 - 0.0026 18.1 0.1 0.012 16.0 0.0 2.1 2 0 0 2 2 2 1 RuvA, C-terminal domain Peptidase_S10 PF00450.22 KFM23301.1 - 6.3e-133 444.2 0.0 7.1e-133 444.0 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase 2OG-FeII_Oxy_4 PF13661.6 KFM23302.1 - 3.5e-11 43.6 0.0 1.1e-10 42.0 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KFM23302.1 - 5.9e-11 43.1 0.0 8.8e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ABATE PF07336.11 KFM23302.1 - 0.0024 18.5 6.2 0.0058 17.3 6.2 1.6 1 0 0 1 1 1 1 Putative stress-induced transcription regulator S1 PF00575.23 KFM23303.1 - 5.4e-17 61.9 1.2 7.2e-10 39.1 0.3 2.3 2 0 0 2 2 2 2 S1 RNA binding domain S1_2 PF13509.6 KFM23303.1 - 0.038 14.0 0.0 5.7 7.1 0.0 2.5 2 0 0 2 2 2 0 S1 domain TOBE_3 PF12857.7 KFM23303.1 - 0.21 11.5 2.6 54 3.8 0.0 3.7 4 0 0 4 4 4 0 TOBE-like domain Zw10 PF06248.13 KFM23304.1 - 4.9e-10 38.6 0.0 0.00011 20.9 0.0 2.2 2 0 0 2 2 2 2 Centromere/kinetochore Zw10 fn3 PF00041.21 KFM23305.1 - 1e-19 70.6 0.6 1.1e-07 32.1 0.0 3.4 3 1 0 3 3 3 3 Fibronectin type III domain Y_Y_Y PF07495.13 KFM23305.1 - 0.17 11.9 0.1 0.76 9.8 0.0 2.1 2 0 0 2 2 2 0 Y_Y_Y domain SWM_repeat PF13753.6 KFM23305.1 - 0.37 11.0 5.1 1.5 9.0 2.0 3.2 4 0 0 4 4 4 0 Putative flagellar system-associated repeat Mrr_cat PF04471.12 KFM23306.1 - 5.7e-05 23.1 0.1 1.3 9.1 0.0 3.2 3 0 0 3 3 3 2 Restriction endonuclease Glucodextran_C PF09985.9 KFM23306.1 - 0.13 11.7 0.4 0.84 9.0 0.1 2.2 2 0 0 2 2 2 0 C-terminal binding-module, SLH-like, of glucodextranase Goodbye PF17109.5 KFM23306.1 - 1.9 8.9 4.0 39 4.7 0.0 4.1 4 1 1 5 5 5 0 fungal STAND N-terminal Goodbye domain fn3 PF00041.21 KFM23307.1 - 1.4e-10 41.4 0.1 0.0096 16.3 0.0 5.2 4 1 1 5 5 5 3 Fibronectin type III domain Y_Y_Y PF07495.13 KFM23307.1 - 0.00033 20.6 0.2 2.4 8.2 0.0 4.2 4 0 0 4 4 4 1 Y_Y_Y domain TcfC PF16967.5 KFM23307.1 - 0.0032 16.9 0.4 1.9 8.1 0.1 3.4 3 0 0 3 3 3 1 E-set like domain fn3_3 PF14686.6 KFM23307.1 - 0.008 15.9 9.0 0.33 10.8 0.1 5.1 6 0 0 6 6 6 1 Polysaccharide lyase family 4, domain II Izumo-Ig PF16706.5 KFM23307.1 - 0.01 15.9 0.1 4.2 7.5 0.0 3.8 4 0 0 4 4 4 0 Izumo-like Immunoglobulin domain SpaA PF17802.1 KFM23307.1 - 0.081 13.3 8.7 19 5.7 0.0 4.5 3 1 1 4 4 4 0 Prealbumin-like fold domain YtkA PF13115.6 KFM23307.1 - 0.15 12.6 0.1 47 4.7 0.0 3.6 4 0 0 4 4 4 0 YtkA-like V-set PF07686.17 KFM23307.1 - 0.97 9.6 5.8 7 6.9 0.1 4.2 5 0 0 5 5 5 0 Immunoglobulin V-set domain PKD PF00801.20 KFM23307.1 - 1.6 8.6 9.3 7.9 6.4 0.3 5.1 5 0 0 5 5 5 0 PKD domain DUF4140 PF13600.6 KFM23307.1 - 3.6 8.1 9.3 1.8 9.1 0.2 4.0 5 0 0 5 5 5 0 N-terminal domain of unknown function (DUF4140) A_deaminase PF00962.22 KFM23308.1 - 1.2e-29 103.7 0.0 6.4e-29 101.3 0.0 2.1 1 1 0 1 1 1 1 Adenosine/AMP deaminase DDHD PF02862.17 KFM23309.1 - 6.5e-15 55.9 0.0 1.5e-14 54.7 0.0 1.6 2 0 0 2 2 2 1 DDHD domain MatE PF01554.18 KFM23311.1 - 6.1e-25 87.7 24.4 8.9e-23 80.7 8.3 2.1 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KFM23311.1 - 1.3e-06 28.5 7.3 1.3e-06 28.5 7.3 3.4 3 2 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain Abhydro_lipase PF04083.16 KFM23313.1 - 1.1e-15 56.9 0.0 2e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 KFM23313.1 - 0.0003 20.1 0.1 0.0082 15.4 0.1 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFM23313.1 - 0.0026 17.4 0.1 0.068 12.8 0.0 2.7 2 1 0 2 2 2 1 alpha/beta hydrolase fold ADK PF00406.22 KFM23314.1 - 2.8e-56 189.8 0.0 3.6e-56 189.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KFM23314.1 - 3.2e-20 72.9 0.0 9.1e-20 71.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 KFM23314.1 - 8.5e-16 57.6 0.0 1.5e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.6 KFM23314.1 - 0.00033 20.8 0.0 0.00089 19.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KFM23314.1 - 0.02 15.4 0.0 0.043 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KFM23314.1 - 0.054 13.4 0.1 0.084 12.8 0.1 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 KFM23314.1 - 0.057 13.5 0.0 0.26 11.4 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF3107 PF11305.8 KFM23314.1 - 0.19 12.0 0.4 1.1 9.5 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3107) Abhydro_lipase PF04083.16 KFM23316.1 - 2.7e-17 62.1 0.0 4.7e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 KFM23316.1 - 0.0013 18.4 0.1 0.078 12.6 0.0 2.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFM23316.1 - 0.0024 17.2 0.3 0.0072 15.6 0.1 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF915 PF06028.11 KFM23316.1 - 0.28 10.5 0.0 0.76 9.1 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF1772 PF08592.11 KFM23317.1 - 1.4e-06 28.7 3.5 1.4e-06 28.7 3.5 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) ERO1 PF04137.15 KFM23318.1 - 7.9e-103 344.3 0.0 9.4e-103 344.1 0.0 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) NUDIX_4 PF14815.6 KFM23319.1 - 1.6e-17 63.4 0.2 5.7e-17 61.7 0.2 1.9 1 1 0 1 1 1 1 NUDIX domain HhH-GPD PF00730.25 KFM23319.1 - 5.8e-15 55.7 0.0 1.5e-14 54.3 0.0 1.7 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KFM23319.1 - 2.1e-07 30.4 0.1 5.9e-07 29.0 0.1 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 KFM23319.1 - 0.017 15.4 2.4 0.017 15.4 2.4 1.8 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III HHH_5 PF14520.6 KFM23319.1 - 0.15 12.7 0.0 1.6 9.4 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix domain Cyto_heme_lyase PF01265.17 KFM23320.1 - 1.5e-51 175.8 9.3 1.4e-28 100.4 0.2 2.2 1 1 1 2 2 2 2 Cytochrome c/c1 heme lyase M16C_assoc PF08367.11 KFM23321.1 - 2.7e-74 249.5 0.0 3.8e-74 249.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 KFM23321.1 - 3.4e-15 56.5 0.2 6.4e-08 32.8 0.0 4.0 4 1 1 5 5 5 3 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KFM23321.1 - 1.6e-05 25.0 0.0 5.2e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) ThiF PF00899.21 KFM23322.1 - 1.9e-48 165.0 0.0 2.3e-48 164.7 0.0 1.0 1 0 0 1 1 1 1 ThiF family 2-Hacid_dh_C PF02826.19 KFM23322.1 - 0.00056 19.3 0.1 0.00085 18.7 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 KFM23322.1 - 0.032 14.5 0.2 5.4 7.3 0.1 2.9 2 1 1 3 3 3 0 TrkA-N domain NAD_binding_7 PF13241.6 KFM23322.1 - 0.058 13.8 0.1 0.24 11.8 0.1 1.8 1 1 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 KFM23322.1 - 0.072 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ELFV_dehydrog PF00208.21 KFM23322.1 - 0.088 12.5 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase FAD_binding_3 PF01494.19 KFM23322.1 - 0.15 11.3 0.4 0.22 10.7 0.4 1.2 1 0 0 1 1 1 0 FAD binding domain Sacchrp_dh_NADP PF03435.18 KFM23322.1 - 0.15 12.3 1.6 3 8.1 1.6 2.2 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain PRA1 PF03208.19 KFM23323.1 - 1.5e-07 31.1 0.0 2.8e-07 30.3 0.0 1.4 1 1 0 1 1 1 1 PRA1 family protein NUMOD3 PF07460.11 KFM23324.1 - 0.097 12.9 0.2 0.18 12.0 0.2 1.4 1 0 0 1 1 1 0 NUMOD3 motif (2 copies) TFIIA PF03153.13 KFM23326.1 - 1.2e-42 147.5 5.4 5.3e-26 92.6 1.8 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit Astro_capsid_p PF12226.8 KFM23326.1 - 6.5 5.8 6.3 8.4 5.4 6.3 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein ANTH PF07651.16 KFM23327.1 - 2.1e-35 122.1 0.2 4.5e-16 58.7 0.0 3.1 1 1 2 3 3 3 3 ANTH domain RRM_1 PF00076.22 KFM23328.1 - 9.2e-29 99.1 0.0 1.1e-14 54.0 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFM23328.1 - 2.8e-07 30.5 0.0 0.013 15.6 0.0 2.1 2 0 0 2 2 2 2 RNA binding motif RRM_7 PF16367.5 KFM23328.1 - 0.0005 20.1 0.0 0.0024 18.0 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif RRM_occluded PF16842.5 KFM23328.1 - 0.0028 17.5 0.0 0.079 12.8 0.0 2.2 2 0 0 2 2 2 1 Occluded RNA-recognition motif PHM7_cyt PF14703.6 KFM23328.1 - 0.05 13.8 0.0 5.2 7.3 0.0 2.7 1 1 2 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter DUF4211 PF13926.6 KFM23328.1 - 0.066 13.3 0.0 0.082 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4211) adh_short PF00106.25 KFM23329.1 - 1.4e-18 67.1 0.0 3.9e-18 65.6 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM23329.1 - 1.1e-11 44.7 0.0 1.8e-11 44.1 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM23329.1 - 3.2e-06 27.2 0.0 2e-05 24.6 0.0 2.1 1 1 0 1 1 1 1 KR domain RHH_5 PF07878.11 KFM23329.1 - 0.057 13.3 0.1 0.057 13.3 0.1 2.5 3 0 0 3 3 3 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 PsbP PF01789.16 KFM23330.1 - 1.9e-30 106.0 0.0 2.4e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 PsbP PsbQ PF05757.11 KFM23330.1 - 0.15 11.8 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) DUF3185 PF11381.8 KFM23330.1 - 2.2 8.4 4.2 0.34 11.0 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) zf-C3HC4_3 PF13920.6 KFM23331.1 - 1.3e-08 34.5 9.9 2.5e-08 33.7 9.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFM23331.1 - 2.4e-07 30.5 11.8 4.3e-07 29.7 11.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM23331.1 - 2.2e-06 27.4 13.1 4.9e-06 26.3 13.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM23331.1 - 5.8e-06 26.2 12.8 1.2e-05 25.1 12.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFM23331.1 - 5.8e-06 26.1 8.0 1.2e-05 25.0 8.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KFM23331.1 - 0.00024 21.4 10.7 0.00044 20.5 10.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KFM23331.1 - 0.00034 20.8 6.3 0.00067 19.9 6.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 KFM23331.1 - 0.00044 20.1 3.0 0.0011 18.7 3.0 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.6 KFM23331.1 - 0.00087 19.3 8.6 0.0017 18.3 8.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Spc7 PF08317.11 KFM23331.1 - 0.019 13.9 0.7 0.019 13.9 0.7 4.2 3 1 1 4 4 4 0 Spc7 kinetochore protein zf-RING_4 PF14570.6 KFM23331.1 - 0.022 14.5 7.4 0.044 13.6 7.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_5 PF17121.5 KFM23331.1 - 0.063 13.2 6.0 0.13 12.2 6.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4407 PF14362.6 KFM23331.1 - 0.088 12.1 43.9 0.089 12.1 10.6 4.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) ADIP PF11559.8 KFM23331.1 - 0.12 12.4 32.7 0.067 13.3 3.7 5.5 3 1 3 6 6 6 0 Afadin- and alpha -actinin-Binding zf-ANAPC11 PF12861.7 KFM23331.1 - 0.28 11.3 3.3 0.52 10.4 3.3 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KFM23331.1 - 0.29 11.3 8.8 0.62 10.3 8.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF2039 PF10217.9 KFM23331.1 - 0.41 11.0 7.1 0.83 10.0 7.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) DUF1272 PF06906.11 KFM23331.1 - 1.3 9.2 7.4 1.8 8.7 6.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1272) Trimer_CC PF08954.11 KFM23331.1 - 1.7 8.3 0.0 1.7 8.3 0.0 4.4 4 1 0 4 4 4 0 Trimerisation motif zf-ribbon_3 PF13248.6 KFM23331.1 - 2.1 7.8 4.1 2.4 7.7 0.8 2.3 2 0 0 2 2 2 0 zinc-ribbon domain TMF_TATA_bd PF12325.8 KFM23331.1 - 5.3 7.3 26.0 12 6.2 0.0 5.4 4 2 1 5 5 5 0 TATA element modulatory factor 1 TATA binding DZR PF12773.7 KFM23331.1 - 6.5 6.9 9.5 17 5.5 9.5 1.7 1 1 0 1 1 1 0 Double zinc ribbon AAA_13 PF13166.6 KFM23331.1 - 9.3 4.7 11.7 1.2 7.7 7.0 1.9 2 0 0 2 2 2 0 AAA domain DUF16 PF01519.16 KFM23331.1 - 9.4 6.8 10.3 5.4 7.6 0.0 4.0 4 1 0 4 4 3 0 Protein of unknown function DUF16 Pkinase PF00069.25 KFM23332.1 - 1.7e-66 224.3 0.0 2.4e-66 223.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM23332.1 - 2.1e-42 145.2 0.0 2.9e-42 144.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Arm PF00514.23 KFM23332.1 - 8.6e-15 54.2 0.3 9.3e-06 25.5 0.0 5.6 5 0 0 5 5 5 3 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KFM23332.1 - 6e-08 32.3 2.0 0.005 17.0 0.0 3.9 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.6 KFM23332.1 - 2.1e-07 31.3 1.6 9e-07 29.3 0.4 8.2 8 1 1 9 9 9 2 HEAT-like repeat HEAT_2 PF13646.6 KFM23332.1 - 1.9e-06 28.2 0.2 1.9e-06 28.2 0.2 5.1 5 0 0 5 5 5 1 HEAT repeats Kinase-like PF14531.6 KFM23332.1 - 4.9e-05 22.8 0.0 7.7e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFM23332.1 - 0.00058 18.7 0.0 0.001 18.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KFM23332.1 - 0.021 14.2 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFM23332.1 - 0.057 12.4 0.1 0.085 11.8 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 KFM23332.1 - 0.075 12.6 0.0 0.2 11.2 0.0 1.7 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 KFM23332.1 - 0.16 11.5 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.22 KFM23332.1 - 0.25 10.9 0.0 0.4 10.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family HORMA PF02301.18 KFM23333.1 - 3.2e-17 62.8 0.1 8.2e-17 61.5 0.1 1.6 1 1 0 1 1 1 1 HORMA domain ATG101 PF07855.12 KFM23333.1 - 0.00025 21.1 0.1 0.00058 19.9 0.1 1.6 1 1 0 1 1 1 1 Autophagy-related protein 101 Picorna_P3A PF06363.11 KFM23333.1 - 0.017 14.9 0.0 0.091 12.6 0.1 2.0 2 0 0 2 2 2 0 Picornaviridae P3A protein E3_UFM1_ligase PF09743.9 KFM23333.1 - 0.04 13.5 0.1 0.084 12.5 0.1 1.6 1 1 0 1 1 1 0 E3 UFM1-protein ligase 1 bacHORMA_2 PF18173.1 KFM23333.1 - 0.055 13.3 0.1 0.089 12.6 0.1 1.4 1 0 0 1 1 1 0 Bacterial HORMA domain 2 Tic22 PF04278.12 KFM23334.1 - 6.7e-46 156.7 0.2 1.1e-39 136.3 0.2 2.1 2 0 0 2 2 2 2 Tic22-like family Phage_holin_7_1 PF16081.5 KFM23334.1 - 3.5 7.8 7.2 2.9 8.1 1.0 2.5 2 0 0 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family FA_hydroxylase PF04116.13 KFM23335.1 - 3.3e-13 50.1 3.8 3.3e-13 50.1 3.8 1.6 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Fcf2 PF08698.11 KFM23336.1 - 2.8e-31 107.7 0.1 5.4e-31 106.9 0.1 1.5 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing TPR_19 PF14559.6 KFM23336.1 - 5.2e-05 23.7 0.2 5.2e-05 23.7 0.2 6.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFM23336.1 - 0.00019 22.0 6.3 0.00019 22.0 6.3 11.0 12 2 1 13 13 13 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFM23336.1 - 0.054 14.3 0.3 0.054 14.3 0.3 11.1 12 1 1 13 13 13 0 Tetratricopeptide repeat F-box PF00646.33 KFM23337.1 - 0.0018 18.1 1.6 0.0042 16.9 1.0 2.0 2 0 0 2 2 2 1 F-box domain Aldolase_II PF00596.21 KFM23338.1 - 4.3e-36 124.6 0.0 7.3e-36 123.9 0.0 1.4 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Hydrolase PF00702.26 KFM23338.1 - 1.8e-07 31.6 0.0 0.001 19.4 0.0 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KFM23338.1 - 0.16 12.1 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase V-SNARE_C PF12352.8 KFM23339.1 - 3.9e-13 49.5 0.8 3.9e-13 49.5 0.8 2.1 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KFM23339.1 - 0.00063 19.6 0.0 0.0014 18.5 0.0 1.6 1 0 0 1 1 1 1 Sec20 T4bSS_IcmS PF12608.8 KFM23339.1 - 0.13 12.6 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Type IVb secretion, IcmS, effector-recruitment Ribosomal_L2_C PF03947.18 KFM23339.1 - 0.24 11.6 0.5 0.38 11.0 0.5 1.3 1 0 0 1 1 1 0 Ribosomal Proteins L2, C-terminal domain Nup35_RRM PF05172.13 KFM23340.1 - 2.3e-09 37.1 0.0 1.4e-08 34.6 0.0 1.9 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 KFM23340.1 - 0.013 15.5 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif XAP5 PF04921.14 KFM23341.1 - 4.1e-75 252.8 0.3 4.1e-75 252.8 0.3 2.2 1 1 1 2 2 2 1 XAP5, circadian clock regulator YchF-GTPase_C PF06071.13 KFM23341.1 - 0.085 13.1 0.5 0.36 11.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF933) DUF4085 PF13315.6 KFM23341.1 - 0.13 11.9 0.1 0.13 11.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4085) DUF4604 PF15377.6 KFM23341.1 - 5.7 7.3 24.0 1.4 9.4 19.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) C2 PF00168.30 KFM23342.1 - 1.8e-22 79.6 0.0 9.9e-18 64.3 0.0 2.3 2 0 0 2 2 2 2 C2 domain SMP_LBD PF17047.5 KFM23342.1 - 3.9e-10 39.5 0.0 2.9e-05 23.6 0.0 2.6 2 1 1 3 3 3 2 Synaptotagmin-like mitochondrial-lipid-binding domain Kelch_4 PF13418.6 KFM23343.1 - 1.2e-28 98.9 6.1 0.00011 22.1 0.1 7.4 5 1 2 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.6 KFM23343.1 - 2.7e-27 94.1 2.7 1.9e-07 31.1 0.1 6.5 7 0 0 7 7 7 5 Kelch motif Kelch_5 PF13854.6 KFM23343.1 - 2.3e-25 88.1 4.4 2e-06 27.7 0.0 6.9 6 1 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 KFM23343.1 - 2.7e-25 88.1 12.6 4.6e-07 30.0 0.1 7.6 8 0 0 8 8 8 5 Galactose oxidase, central domain Kelch_2 PF07646.15 KFM23343.1 - 5.1e-17 61.1 3.6 7.3e-05 22.6 0.1 5.8 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 KFM23343.1 - 1.3e-16 59.9 15.5 6.4e-06 25.6 2.3 7.1 6 3 0 6 6 6 4 Kelch motif IQ PF00612.27 KFM23343.1 - 0.00012 21.6 0.2 0.00012 21.6 0.2 2.0 2 0 0 2 2 2 1 IQ calmodulin-binding motif TPX2_importin PF12214.8 KFM23344.1 - 2.1e-08 34.5 1.6 3.9e-08 33.7 1.6 1.5 1 0 0 1 1 1 1 Cell cycle regulated microtubule associated protein DUF3498 PF12004.8 KFM23344.1 - 1.3 8.2 8.1 1.5 7.9 8.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) Peptidase_C1 PF00112.23 KFM23345.1 - 1.3e-57 195.4 0.0 1.9e-57 194.9 0.0 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Granulin PF00396.18 KFM23345.1 - 2.4e-10 40.6 23.6 2.4e-10 40.6 23.6 1.9 2 0 0 2 2 2 1 Granulin Inhibitor_I29 PF08246.12 KFM23345.1 - 4.4e-10 39.8 0.6 6.2e-10 39.4 0.6 1.2 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Cry1Ac_D5 PF17997.1 KFM23345.1 - 0.097 12.5 0.1 14 5.5 0.0 2.2 1 1 0 2 2 2 0 Insecticidal delta-endotoxin CryIA(c) domain 5 Peptidase_C1_2 PF03051.15 KFM23345.1 - 0.2 10.4 0.0 0.3 9.8 0.0 1.1 1 0 0 1 1 1 0 Peptidase C1-like family Cupin_1 PF00190.22 KFM23346.1 - 1.2e-09 37.9 0.1 1.8e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 Cupin Rubella_E1 PF05748.11 KFM23346.1 - 0.0073 15.2 0.6 0.013 14.4 0.1 1.5 1 1 0 2 2 2 1 Rubella membrane glycoprotein E1 Cupin_2 PF07883.11 KFM23346.1 - 0.083 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Cupin domain Pkinase_Tyr PF07714.17 KFM23347.1 - 3.3e-28 98.7 0.0 1.1e-17 64.2 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KFM23347.1 - 5.3e-23 81.7 0.0 4.3e-17 62.3 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Ribosomal_S4Pg PF11993.8 KFM23347.1 - 0.067 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal S4P (gammaproteobacterial) Ldh_1_N PF00056.23 KFM23348.1 - 3.1e-42 144.0 0.0 4.6e-42 143.5 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KFM23348.1 - 2.1e-41 141.7 0.0 3e-41 141.1 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain SAP PF02037.27 KFM23348.1 - 1.2e-06 28.1 0.3 3.4e-06 26.7 0.1 1.9 2 0 0 2 2 2 1 SAP domain Semialdhyde_dh PF01118.24 KFM23348.1 - 0.01 16.3 0.4 0.032 14.7 0.1 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KFM23348.1 - 0.2 10.6 0.0 0.31 10.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF565 PF04483.12 KFM23349.1 - 3.3e-11 43.6 0.1 4.2e-11 43.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF565) Acetyltransf_1 PF00583.25 KFM23350.1 - 8.9e-14 51.7 0.0 1e-13 51.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFM23350.1 - 9.4e-06 25.6 0.0 1.2e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFM23350.1 - 1e-05 25.9 0.0 1.6e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KFM23350.1 - 0.0009 19.3 0.0 0.0014 18.7 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KFM23350.1 - 0.01 15.9 0.0 0.012 15.7 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF212 PF02681.14 KFM23351.1 - 3.5e-46 156.5 0.7 4.1e-46 156.3 0.7 1.1 1 0 0 1 1 1 1 Divergent PAP2 family PAP2 PF01569.21 KFM23351.1 - 1.5 8.6 9.7 8 6.2 0.2 2.7 2 1 0 2 2 2 0 PAP2 superfamily SRP9-21 PF05486.12 KFM23352.1 - 1.1e-10 41.7 4.1 5.1e-09 36.4 4.1 2.1 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) DUF4336 PF14234.6 KFM23353.1 - 1.7e-84 283.7 0.3 1.3e-66 225.0 0.3 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4336) Rep_fac_C PF08542.11 KFM23353.1 - 6.4e-22 77.8 0.0 1.5e-21 76.6 0.0 1.7 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA PF00004.29 KFM23353.1 - 7.2e-14 52.3 0.0 1.1e-13 51.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KFM23353.1 - 1.7e-09 37.7 0.0 7.5e-09 35.6 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.6 KFM23353.1 - 4e-05 24.1 0.0 0.00079 19.8 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 KFM23353.1 - 4.1e-05 23.6 0.0 6.4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KFM23353.1 - 7.2e-05 23.1 0.1 0.019 15.2 0.0 2.4 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KFM23353.1 - 0.00011 21.6 0.0 0.00062 19.2 0.0 1.9 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 KFM23353.1 - 0.00014 21.9 0.0 0.00023 21.1 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain Viral_helicase1 PF01443.18 KFM23353.1 - 0.00039 20.2 0.0 0.00059 19.6 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.12 KFM23353.1 - 0.0013 18.5 0.0 0.0033 17.2 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 KFM23353.1 - 0.0031 17.8 0.2 0.0092 16.3 0.2 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFM23353.1 - 0.0039 17.7 0.0 0.0069 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFM23353.1 - 0.007 16.1 0.6 0.044 13.5 0.6 2.1 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 KFM23353.1 - 0.011 15.6 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KFM23353.1 - 0.011 15.4 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KFM23353.1 - 0.015 15.1 0.0 0.023 14.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_assoc_2 PF16193.5 KFM23353.1 - 0.026 14.9 0.0 0.061 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA C-terminal domain AAA_7 PF12775.7 KFM23353.1 - 0.041 13.4 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 KFM23353.1 - 0.044 13.2 0.0 1 8.7 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein NTPase_1 PF03266.15 KFM23353.1 - 0.051 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_33 PF13671.6 KFM23353.1 - 0.059 13.5 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 KFM23353.1 - 0.081 11.9 0.0 0.22 10.5 0.0 1.5 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 KFM23353.1 - 0.087 12.4 0.0 0.29 10.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KFM23353.1 - 0.096 12.7 0.0 0.28 11.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DEAD PF00270.29 KFM23353.1 - 0.13 12.0 0.1 2.9 7.6 0.0 2.2 1 1 1 2 2 2 0 DEAD/DEAH box helicase ubiquitin PF00240.23 KFM23354.1 - 6.6e-12 45.0 0.2 7.6e-12 44.8 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KFM23354.1 - 3.4e-05 23.6 0.0 4.8e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 KFM23354.1 - 0.081 13.0 0.2 2.4 8.3 0.2 2.1 1 1 0 1 1 1 0 Ubiquitin-like domain UN_NPL4 PF11543.8 KFM23354.1 - 0.17 12.4 0.0 0.21 12.1 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Longin PF13774.6 KFM23355.1 - 2.3e-20 72.4 0.1 3.6e-20 71.8 0.1 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 KFM23355.1 - 4.7e-18 64.8 0.2 7.4e-18 64.1 0.2 1.3 1 0 0 1 1 1 1 Synaptobrevin Fzo_mitofusin PF04799.13 KFM23355.1 - 0.0099 15.4 2.8 0.028 14.0 1.3 2.0 2 0 0 2 2 2 1 fzo-like conserved region DUF2924 PF11149.8 KFM23355.1 - 0.017 15.5 0.2 0.038 14.4 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2924) ORF6N PF10543.9 KFM23355.1 - 0.11 12.7 0.1 0.31 11.3 0.0 1.8 2 0 0 2 2 2 0 ORF6N domain THF_DHG_CYH_C PF02882.19 KFM23357.1 - 5.9e-47 159.0 5.1 1.4e-29 102.4 2.7 2.2 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KFM23357.1 - 4.6e-28 97.8 0.0 7.6e-28 97.1 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Elf4 PF07011.11 KFM23358.1 - 9.1e-11 41.5 0.0 9.9e-11 41.4 0.0 1.1 1 0 0 1 1 1 1 Early Flowering 4 domain SSXT PF05030.12 KFM23358.1 - 4.5e-06 26.2 0.1 7e-06 25.6 0.1 1.2 1 0 0 1 1 1 1 SSXT protein (N-terminal region) FlaC_arch PF05377.11 KFM23358.1 - 0.033 14.6 0.0 0.086 13.2 0.0 1.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF5344 PF17279.2 KFM23358.1 - 0.1 13.2 0.1 0.13 12.8 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5344) ACBP PF00887.19 KFM23359.1 - 9.9e-22 77.0 0.0 4.1e-21 75.0 0.0 1.9 2 1 0 2 2 2 1 Acyl CoA binding protein Ank_5 PF13857.6 KFM23359.1 - 4.7e-10 39.5 0.6 9.5e-10 38.5 0.6 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFM23359.1 - 2.6e-08 34.2 0.1 6e-07 29.9 0.0 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM23359.1 - 5.2e-07 30.2 0.0 1e-06 29.2 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KFM23359.1 - 1e-06 28.9 0.7 0.023 15.2 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KFM23359.1 - 4.4e-05 23.6 0.2 0.068 13.8 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat DHC_N1 PF08385.12 KFM23361.1 - 0.28 9.8 0.0 3.8 6.0 0.0 2.2 2 0 0 2 2 2 0 Dynein heavy chain, N-terminal region 1 PBP PF01161.20 KFM23362.1 - 3e-18 66.4 0.1 3.5e-18 66.2 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF5601 PF18151.1 KFM23363.1 - 3.1e-13 49.8 0.0 1.7e-12 47.5 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF5601) VPS9 PF02204.18 KFM23363.1 - 1.2e-09 38.3 0.0 1.5e-05 25.2 0.0 2.4 1 1 1 2 2 2 2 Vacuolar sorting protein 9 (VPS9) domain GOLGA2L5 PF15070.6 KFM23363.1 - 0.21 10.2 1.7 0.23 10.1 0.4 1.6 2 0 0 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 NDK PF00334.19 KFM23364.1 - 6.3e-53 178.4 0.0 8.4e-53 178.0 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase G3P_acyltransf PF02660.15 KFM23364.1 - 0.054 13.6 0.6 0.096 12.7 0.1 1.6 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase Ribosomal_L7Ae PF01248.26 KFM23365.1 - 4e-22 77.8 0.5 1.1e-21 76.3 0.5 1.7 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Cellulase PF00150.18 KFM23365.1 - 0.0035 16.8 0.0 0.0039 16.7 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cpn60_TCP1 PF00118.24 KFM23365.1 - 0.041 12.5 3.7 0.06 12.0 3.7 1.1 1 0 0 1 1 1 0 TCP-1/cpn60 chaperonin family DUF3723 PF12520.8 KFM23365.1 - 0.068 11.8 1.9 0.097 11.3 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3723) PEP-utilizers PF00391.23 KFM23365.1 - 0.16 11.7 0.7 2.1 8.1 0.0 2.6 3 0 0 3 3 3 0 PEP-utilising enzyme, mobile domain ATPase_2 PF01637.18 KFM23365.1 - 0.86 9.5 3.5 1.3 8.9 3.5 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea JAB PF01398.21 KFM23366.1 - 3e-20 72.3 0.0 5.1e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 KFM23366.1 - 6.8e-16 58.5 0.1 9.2e-16 58.1 0.1 1.2 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.6 KFM23366.1 - 3.7e-05 23.5 2.6 6.3e-05 22.7 0.0 2.4 3 0 0 3 3 3 1 Prokaryotic homologs of the JAB domain TPR_16 PF13432.6 KFM23367.1 - 1.5e-10 41.5 16.2 1.6e-07 31.9 3.6 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFM23367.1 - 4e-09 36.2 0.3 0.045 14.1 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFM23367.1 - 2e-06 28.2 10.9 0.00015 22.2 0.5 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFM23367.1 - 1.4e-05 24.9 0.9 9.5 6.6 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFM23367.1 - 2.4e-05 24.5 9.6 2.7 8.4 0.6 4.2 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFM23367.1 - 0.0026 18.4 0.7 0.0026 18.4 0.7 4.5 3 3 3 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFM23367.1 - 0.0027 17.5 0.2 3.4 7.7 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat BTAD PF03704.17 KFM23367.1 - 0.0046 17.4 0.6 0.0046 17.4 0.6 2.6 2 1 0 2 2 2 1 Bacterial transcriptional activator domain NARP1 PF12569.8 KFM23367.1 - 0.0055 15.7 0.0 1.3 7.9 0.0 2.2 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_9 PF13371.6 KFM23367.1 - 0.0089 16.1 11.9 0.091 12.9 1.0 3.7 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFM23367.1 - 0.014 15.5 0.1 7 7.1 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFM23367.1 - 0.019 14.9 3.6 9.5 6.5 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 KFM23367.1 - 0.039 13.6 0.3 0.1 12.3 0.1 1.7 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain Pentapeptide_2 PF01469.18 KFM23368.1 - 0.00041 20.2 13.9 0.00054 19.8 13.9 1.1 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) ubiquitin PF00240.23 KFM23369.1 - 1.7e-07 30.9 0.0 2.7e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Ldr_toxin PF13940.6 KFM23369.1 - 0.18 11.9 0.0 0.39 10.8 0.0 1.6 1 0 0 1 1 1 0 Toxin Ldr, type I toxin-antitoxin system ABC2_membrane PF01061.24 KFM23370.1 - 1.6e-33 115.9 2.1 2.3e-33 115.4 2.1 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KFM23370.1 - 1.5e-26 93.5 0.0 2.5e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KFM23370.1 - 1.5e-05 24.9 2.0 0.08 12.7 0.0 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 KFM23370.1 - 3e-05 23.3 4.1 4.3e-05 22.8 4.1 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_16 PF13191.6 KFM23370.1 - 0.00041 20.8 1.1 0.0011 19.4 1.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KFM23370.1 - 0.00057 19.8 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase Rad17 PF03215.15 KFM23370.1 - 0.00083 19.3 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 KFM23370.1 - 0.0024 18.2 0.0 0.0096 16.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 KFM23370.1 - 0.044 12.8 0.0 0.077 12.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 KFM23370.1 - 0.049 14.1 0.1 0.083 13.4 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KFM23370.1 - 0.063 13.0 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 KFM23370.1 - 0.065 13.8 0.0 0.26 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 KFM23370.1 - 0.077 12.4 0.1 1.1 8.6 0.1 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 KFM23370.1 - 0.085 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KFM23370.1 - 0.11 12.7 0.3 0.35 11.0 0.0 2.1 3 0 0 3 3 1 0 AAA domain MMR_HSR1 PF01926.23 KFM23370.1 - 0.11 12.5 0.1 0.24 11.5 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase dNK PF01712.19 KFM23370.1 - 0.12 12.3 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Deoxynucleoside kinase AFG1_ATPase PF03969.16 KFM23370.1 - 0.15 10.9 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 AFG1-like ATPase NTPase_1 PF03266.15 KFM23370.1 - 0.17 11.8 0.0 7 6.5 0.0 2.3 2 0 0 2 2 2 0 NTPase ABC2_membrane_2 PF12679.7 KFM23370.1 - 0.7 9.1 8.4 0.034 13.4 3.0 1.5 2 0 0 2 2 1 0 ABC-2 family transporter protein REF PF05755.12 KFM23371.1 - 6.4e-09 35.9 6.3 2.5e-08 34.0 6.3 2.0 1 1 0 1 1 1 1 Rubber elongation factor protein (REF) TetR_C_24 PF17932.1 KFM23371.1 - 0.021 15.1 0.2 0.042 14.1 0.2 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Usp PF00582.26 KFM23372.1 - 6.2e-24 85.1 1.2 1.9e-23 83.5 1.2 1.9 1 1 0 1 1 1 1 Universal stress protein family Sua5_yciO_yrdC PF01300.18 KFM23372.1 - 1.5e-10 40.9 0.0 4.5e-05 23.0 0.0 2.4 1 1 1 2 2 2 2 Telomere recombination SNARE_assoc PF09335.11 KFM23373.1 - 1.5e-14 54.5 7.3 2.8e-09 37.5 0.7 2.4 2 0 0 2 2 2 2 SNARE associated Golgi protein BCNT PF07572.12 KFM23374.1 - 2.3e-24 85.3 0.4 3.9e-24 84.5 0.4 1.4 1 0 0 1 1 1 1 Bucentaur or craniofacial development PSII_Pbs27 PF13326.6 KFM23375.1 - 7.1e-18 65.3 0.2 8.2e-18 65.1 0.2 1.0 1 0 0 1 1 1 1 Photosystem II Pbs27 Med9 PF07544.13 KFM23375.1 - 0.039 14.1 0.3 0.12 12.5 0.2 1.8 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 LMBR1 PF04791.16 KFM23376.1 - 2.3e-65 221.5 44.4 8.9e-40 137.1 11.6 3.0 1 1 2 3 3 3 3 LMBR1-like membrane protein SNF2_N PF00176.23 KFM23377.1 - 5e-45 153.7 0.0 9.5e-45 152.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF3535 PF12054.8 KFM23377.1 - 9.6e-21 74.5 0.0 1.2e-16 61.0 0.0 3.5 4 0 0 4 4 4 2 Domain of unknown function (DUF3535) Helicase_C PF00271.31 KFM23377.1 - 5.3e-10 39.6 0.0 9.5e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT_2 PF13646.6 KFM23377.1 - 0.0029 17.9 0.1 0.0029 17.9 0.1 7.9 6 3 2 8 8 8 1 HEAT repeats HEAT PF02985.22 KFM23377.1 - 0.034 14.4 0.2 0.034 14.4 0.2 8.6 8 0 0 8 8 8 0 HEAT repeat RRP36 PF06102.12 KFM23378.1 - 4e-44 150.5 18.8 5.2e-44 150.1 18.8 1.1 1 0 0 1 1 1 1 rRNA biogenesis protein RRP36 Yuri_gagarin PF15934.5 KFM23378.1 - 0.05 13.4 5.5 0.23 11.3 5.5 1.8 1 1 0 1 1 1 0 Yuri gagarin 7kD_DNA_binding PF02294.18 KFM23379.1 - 0.26 11.3 0.0 0.44 10.6 0.0 1.3 1 0 0 1 1 1 0 7kD DNA-binding domain ribosomal_L24 PF17136.4 KFM23380.1 - 2.1e-16 60.1 0.0 3.8e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 KFM23380.1 - 5.5e-08 32.5 2.0 1e-07 31.6 2.0 1.5 1 0 0 1 1 1 1 KOW motif PP1_bind PF15276.6 KFM23380.1 - 0.028 14.7 0.9 1.5 9.1 0.0 2.5 1 1 1 2 2 2 0 Protein phosphatase 1 binding PP-binding PF00550.25 KFM23381.1 - 1e-11 45.0 0.4 1.6e-11 44.4 0.4 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 KFM23381.1 - 0.00041 20.5 0.5 0.00091 19.4 0.6 1.6 1 1 1 2 2 2 1 Acyl-carrier Caskin-Pro-rich PF16907.5 KFM23382.1 - 2.1 8.9 7.3 28 5.3 0.4 3.2 3 0 0 3 3 3 0 Proline rich region of Caskin proteins EamA PF00892.20 KFM23383.1 - 4.6e-17 62.5 33.1 1.2e-10 41.7 18.6 2.2 2 0 0 2 2 2 2 EamA-like transporter family TPR_11 PF13414.6 KFM23384.1 - 5.3e-05 22.8 3.3 0.087 12.5 0.0 5.1 5 0 0 5 5 5 1 TPR repeat TPR_19 PF14559.6 KFM23384.1 - 0.00018 21.9 1.8 0.00018 21.9 1.8 4.8 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFM23384.1 - 0.017 15.4 4.0 0.017 15.4 4.0 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFM23384.1 - 0.018 14.8 3.9 0.56 10.1 0.2 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFM23384.1 - 0.02 15.3 0.1 0.02 15.3 0.1 3.6 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFM23384.1 - 0.021 15.5 0.3 0.021 15.5 0.3 5.2 6 2 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFM23384.1 - 0.05 13.7 0.8 0.05 13.7 0.8 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFM23384.1 - 0.15 12.3 5.1 1.1 9.6 0.1 4.4 6 0 0 6 6 6 0 Tetratricopeptide repeat FAD_binding_1 PF00667.20 KFM23386.1 - 3e-37 128.3 0.0 4.2e-37 127.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KFM23386.1 - 9.8e-25 87.4 0.0 1.6e-24 86.7 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KFM23386.1 - 2.4e-11 44.3 0.0 4.7e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KFM23386.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain Ras PF00071.22 KFM23387.1 - 8.8e-58 194.5 0.0 1.1e-57 194.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM23387.1 - 3.6e-29 101.4 0.0 5.5e-29 100.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM23387.1 - 2.9e-11 43.1 0.0 3.6e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFM23387.1 - 0.0053 16.3 0.0 0.0069 15.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFM23387.1 - 0.024 14.7 0.0 0.041 14.0 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFM23387.1 - 0.028 13.8 0.0 0.034 13.5 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region TetR_C_16 PF17920.1 KFM23387.1 - 0.12 12.7 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Epimerase PF01370.21 KFM23388.1 - 5.1e-47 160.4 0.0 6.3e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFM23388.1 - 1.2e-28 100.5 0.0 3.5e-27 95.7 0.0 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KFM23388.1 - 2.2e-11 43.3 0.0 2.7e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KFM23388.1 - 3.1e-07 30.5 0.0 4.2e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KFM23388.1 - 9e-05 21.8 0.0 0.005 16.0 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.17 KFM23388.1 - 0.00022 20.4 0.0 0.00054 19.1 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KFM23388.1 - 0.00024 20.4 0.0 0.0073 15.5 0.0 2.2 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KFM23388.1 - 0.0024 17.5 0.0 0.004 16.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KFM23388.1 - 0.069 12.6 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase Pescadillo_N PF06732.11 KFM23390.1 - 5.5e-90 301.6 0.1 1.5e-58 198.5 0.0 2.1 1 1 1 2 2 2 2 Pescadillo N-terminus BRCT_2 PF16589.5 KFM23390.1 - 0.0013 19.0 0.0 0.0022 18.4 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Tombus_movement PF05318.12 KFM23391.1 - 0.16 12.8 1.0 0.18 12.7 1.0 1.1 1 0 0 1 1 1 0 Tombusvirus movement protein DWNN PF08783.11 KFM23392.1 - 2.7e-19 69.2 0.0 3.6e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 KFM23392.1 - 0.00033 20.4 0.1 0.00051 19.8 0.1 1.3 1 0 0 1 1 1 1 Zinc knuckle Methyltransf_25 PF13649.6 KFM23394.1 - 2.6e-14 53.7 1.0 1.5e-13 51.2 0.1 2.8 3 0 0 3 3 3 1 Methyltransferase domain PrmA PF06325.13 KFM23394.1 - 7.6e-12 45.2 0.1 1.3e-11 44.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KFM23394.1 - 2.2e-11 44.2 0.1 1e-10 42.1 0.1 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM23394.1 - 1.4e-10 41.2 0.0 3.8e-10 39.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 KFM23394.1 - 2.4e-08 33.6 0.0 5.5e-08 32.4 0.0 1.5 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KFM23394.1 - 9.4e-08 32.1 0.0 1.7e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFM23394.1 - 7.1e-07 28.9 0.1 1.4e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KFM23394.1 - 7.3e-07 29.9 0.4 2.8e-05 24.8 0.0 3.3 4 0 0 4 4 4 1 Methyltransferase domain PCMT PF01135.19 KFM23394.1 - 1.9e-06 27.8 0.0 2.9e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 KFM23394.1 - 9.4e-05 22.4 0.0 0.00016 21.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KFM23394.1 - 0.00023 20.8 0.1 0.00043 20.0 0.1 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Ubie_methyltran PF01209.18 KFM23394.1 - 0.00031 20.1 0.0 0.00048 19.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 KFM23394.1 - 0.0048 16.9 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KFM23394.1 - 0.0051 15.8 0.0 0.0075 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_16 PF10294.9 KFM23394.1 - 0.013 15.2 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Met_10 PF02475.16 KFM23394.1 - 0.025 14.3 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein FtsJ PF01728.19 KFM23394.1 - 0.025 14.7 0.0 0.044 13.9 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase UPF0020 PF01170.18 KFM23394.1 - 0.13 11.9 0.0 0.33 10.6 0.0 1.7 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 TehB PF03848.14 KFM23394.1 - 0.16 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Sec10 PF07393.11 KFM23395.1 - 1e-47 163.1 0.0 2e-25 89.3 0.0 2.6 3 0 0 3 3 3 2 Exocyst complex component Sec10 RRM_1 PF00076.22 KFM23396.1 - 9.5e-15 54.2 0.1 3.7e-05 23.4 0.0 3.8 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RAD51_interact PF15696.5 KFM23396.1 - 0.095 12.8 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 RAD51 interacting motif Methyltransf_11 PF08241.12 KFM23398.1 - 1.2e-17 64.3 0.0 2.1e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM23398.1 - 2.1e-17 63.4 0.0 3e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM23398.1 - 1.1e-15 58.1 0.1 1.8e-15 57.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM23398.1 - 5.6e-13 49.5 0.0 8.3e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM23398.1 - 1.6e-12 47.5 0.0 1.9e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KFM23398.1 - 1.4e-07 31.1 0.0 1.6e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 KFM23398.1 - 5e-06 26.1 0.1 7e-06 25.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KFM23398.1 - 4.5e-05 23.1 0.1 6.7e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 KFM23398.1 - 0.00011 21.9 0.0 0.00015 21.5 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_9 PF08003.11 KFM23398.1 - 0.00013 21.0 0.0 0.00018 20.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 KFM23398.1 - 0.00026 21.0 0.0 0.00032 20.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 KFM23398.1 - 0.00067 19.4 0.0 0.00097 18.8 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) MetW PF07021.12 KFM23398.1 - 0.0013 18.3 0.1 0.0028 17.3 0.1 1.5 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_16 PF10294.9 KFM23398.1 - 0.0017 18.1 0.1 0.0041 16.9 0.1 1.6 1 1 0 1 1 1 1 Lysine methyltransferase Ubie_methyltran PF01209.18 KFM23398.1 - 0.0071 15.7 0.0 0.0095 15.3 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 KFM23398.1 - 0.016 15.1 0.0 0.024 14.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.10 KFM23398.1 - 0.021 14.4 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase ComFB PF10719.9 KFM23398.1 - 0.032 14.3 0.0 0.06 13.4 0.0 1.4 1 0 0 1 1 1 0 Late competence development protein ComFB LMWPc PF01451.21 KFM23399.1 - 2.3e-15 57.2 0.0 9.4e-14 52.0 0.0 2.5 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase TFIIS_C PF01096.18 KFM23400.1 - 2.2e-16 59.4 1.1 3.4e-16 58.8 1.1 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Zn-ribbon_8 PF09723.10 KFM23400.1 - 0.003 17.6 2.9 2 8.6 0.0 2.9 3 0 0 3 3 3 2 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 KFM23400.1 - 0.0044 17.0 0.3 0.0093 15.9 0.3 1.6 1 0 0 1 1 1 1 Transposase zinc-ribbon domain DUF2387 PF09526.10 KFM23400.1 - 0.019 15.1 0.5 0.04 14.1 0.5 1.5 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) zf-Mss51 PF13824.6 KFM23400.1 - 0.033 14.3 2.1 4.1 7.6 0.3 2.4 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-ribbon_3 PF13248.6 KFM23400.1 - 0.034 13.5 3.0 1.4 8.4 0.2 3.0 3 0 0 3 3 3 0 zinc-ribbon domain DZR PF12773.7 KFM23400.1 - 0.041 13.9 1.2 0.26 11.4 1.3 2.1 2 1 0 2 2 2 0 Double zinc ribbon CpXC PF14353.6 KFM23400.1 - 0.099 12.7 1.4 1.1 9.4 0.2 2.3 1 1 1 2 2 2 0 CpXC protein tRNA-synt_1f PF01921.18 KFM23400.1 - 0.12 11.2 0.1 0.13 11.2 0.1 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (K) Rubredoxin_2 PF18073.1 KFM23400.1 - 0.15 11.8 4.0 1.6 8.5 0.8 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain A2L_zn_ribbon PF08792.10 KFM23400.1 - 0.16 11.7 3.9 1.3 8.9 0.1 2.8 3 0 0 3 3 3 0 A2L zinc ribbon domain RNA_POL_M_15KD PF02150.16 KFM23400.1 - 0.34 10.8 3.9 6.7 6.7 0.0 3.0 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit zf-RRN7 PF11781.8 KFM23400.1 - 0.53 10.0 6.5 22 4.9 6.7 3.0 2 1 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DUF35_N PF12172.8 KFM23400.1 - 0.72 9.8 3.3 8.5 6.4 0.1 2.8 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zinc_ribbon_2 PF13240.6 KFM23400.1 - 2.4 8.0 12.5 3.3 7.6 1.6 3.0 3 0 0 3 3 3 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 KFM23400.1 - 2.6 7.6 7.2 8.1 6.1 0.5 3.0 2 1 1 3 3 3 0 TFIIB zinc-binding URO-D PF01208.17 KFM23401.1 - 1.6e-89 300.5 0.0 1.8e-89 300.3 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) DUF4200 PF13863.6 KFM23403.1 - 1.3e-17 64.3 15.7 1.3e-17 64.3 15.7 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4200) SnoaL_4 PF13577.6 KFM23403.1 - 0.007 16.5 0.5 0.007 16.5 0.5 1.9 2 1 1 3 3 3 1 SnoaL-like domain MitMem_reg PF13012.6 KFM23403.1 - 0.34 11.3 2.6 1.1 9.6 0.4 2.3 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function DUF641 PF04859.12 KFM23403.1 - 0.77 10.1 18.8 0.046 14.0 3.2 3.1 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) APG6_N PF17675.1 KFM23403.1 - 6.6 7.3 23.4 0.12 12.9 1.7 3.1 1 1 2 3 3 3 0 Apg6 coiled-coil region AAA_13 PF13166.6 KFM23403.1 - 8 5.0 13.6 4.4 5.8 6.2 2.1 1 1 1 2 2 2 0 AAA domain APG6 PF04111.12 KFM23404.1 - 2.1e-48 164.6 0.0 2.8e-48 164.2 0.0 1.1 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 KFM23404.1 - 0.013 16.0 0.0 0.024 15.2 0.0 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Use1 PF09753.9 KFM23405.1 - 3.2e-12 46.7 0.0 2e-11 44.1 0.0 2.0 1 1 1 2 2 2 1 Membrane fusion protein Use1 Vac7 PF12751.7 KFM23405.1 - 0.1 12.0 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 PikAIV_N PF18605.1 KFM23405.1 - 0.41 10.3 0.2 0.41 10.3 0.2 2.2 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain GGACT PF06094.12 KFM23406.1 - 2.4e-20 73.3 0.1 3.2e-20 72.9 0.1 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Tocopherol_cycl PF14249.6 KFM23407.1 - 1.2e-119 399.4 2.6 5.9e-93 311.7 1.9 2.0 1 1 1 2 2 2 2 Tocopherol cyclase PQ-loop PF04193.14 KFM23409.1 - 8.9e-31 105.5 0.0 1.2e-17 63.5 0.0 2.9 3 0 0 3 3 3 2 PQ loop repeat DUF4728 PF15860.5 KFM23409.1 - 0.14 12.9 0.4 29 5.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4728) 3Beta_HSD PF01073.19 KFM23410.1 - 1.5e-63 214.5 0.0 1.8e-63 214.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KFM23410.1 - 2.4e-29 102.5 0.3 3.2e-29 102.1 0.3 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KFM23410.1 - 1.2e-12 47.6 0.4 1.8e-12 47.0 0.4 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KFM23410.1 - 2.1e-10 40.3 1.4 4.8e-09 35.8 1.4 2.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KFM23410.1 - 2.9e-09 37.1 0.6 4.2e-09 36.5 0.6 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KFM23410.1 - 1e-07 31.7 0.1 8.2e-07 28.7 0.2 2.4 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KFM23410.1 - 4.4e-07 29.7 1.9 1e-06 28.5 1.9 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 KFM23410.1 - 4.4e-07 29.3 0.1 1.5e-06 27.6 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein 2-Hacid_dh_C PF02826.19 KFM23410.1 - 0.001 18.5 0.1 0.0018 17.7 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain KR PF08659.10 KFM23410.1 - 0.0018 18.2 1.0 0.0027 17.6 0.2 1.6 1 1 1 2 2 2 1 KR domain TrkA_N PF02254.18 KFM23410.1 - 0.002 18.4 0.5 0.0038 17.5 0.5 1.5 1 0 0 1 1 1 1 TrkA-N domain ArsB PF02040.15 KFM23410.1 - 0.0043 16.4 0.6 0.0067 15.8 0.6 1.2 1 0 0 1 1 1 1 Arsenical pump membrane protein adh_short PF00106.25 KFM23410.1 - 0.0066 15.9 0.4 0.011 15.2 0.4 1.5 1 0 0 1 1 1 1 short chain dehydrogenase AlaDh_PNT_C PF01262.21 KFM23410.1 - 0.026 13.8 1.5 0.043 13.1 1.5 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UPF0146 PF03686.13 KFM23410.1 - 0.046 13.6 0.1 0.13 12.1 0.1 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0146) TBCC PF07986.12 KFM23411.1 - 2e-18 66.3 0.3 3.1e-18 65.6 0.3 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C LNS2 PF08235.13 KFM23412.1 - 3e-08 33.4 0.0 3.3e-07 30.0 0.0 2.3 1 1 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Hydrolase PF00702.26 KFM23412.1 - 0.00016 22.0 0.7 0.0024 18.2 0.1 2.5 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 KFM23412.1 - 0.011 15.3 0.0 0.034 13.7 0.0 1.7 1 1 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) TonB_C PF03544.14 KFM23412.1 - 0.057 13.9 0.0 2.3 8.7 0.0 2.6 2 0 0 2 2 2 0 Gram-negative bacterial TonB protein C-terminal PCI PF01399.27 KFM23413.1 - 2.9e-19 69.5 0.0 6.2e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 KFM23413.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family TPR_6 PF13174.6 KFM23413.1 - 0.47 11.2 2.4 40 5.1 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat RES PF08808.11 KFM23416.1 - 0.025 14.5 0.2 0.052 13.4 0.2 1.7 1 1 0 1 1 1 0 RES domain ABC_tran PF00005.27 KFM23419.1 - 1.5e-43 148.6 0.1 4.3e-24 85.6 0.0 3.3 2 1 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 KFM23419.1 - 3.2e-25 89.0 59.5 1.5e-16 60.5 25.2 3.6 3 1 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.6 KFM23419.1 - 3.7e-23 82.8 0.3 7.3e-07 29.3 0.0 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KFM23419.1 - 2.5e-05 24.7 0.0 0.18 12.2 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KFM23419.1 - 7.5e-05 22.4 2.8 0.31 10.8 0.2 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KFM23419.1 - 0.00011 22.7 4.9 0.13 12.7 0.5 2.2 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KFM23419.1 - 0.00016 21.0 0.0 0.12 11.6 0.0 2.2 2 0 0 2 2 2 2 Zeta toxin AAA_30 PF13604.6 KFM23419.1 - 0.00036 20.3 2.0 0.27 10.9 0.1 2.4 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 KFM23419.1 - 0.00044 19.8 0.1 11 5.4 0.0 4.0 4 0 0 4 4 4 0 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KFM23419.1 - 0.001 19.0 2.1 0.92 9.4 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 KFM23419.1 - 0.0017 18.1 0.0 10 5.7 0.1 3.7 4 0 0 4 4 4 0 AAA ATPase domain IstB_IS21 PF01695.17 KFM23419.1 - 0.0036 17.0 0.1 38 4.0 0.1 4.0 4 0 0 4 4 4 0 IstB-like ATP binding protein SRP54 PF00448.22 KFM23419.1 - 0.0044 16.7 0.5 2.5 7.7 0.0 2.3 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_10 PF12846.7 KFM23419.1 - 0.013 14.5 1.0 1.7 7.4 0.2 2.1 2 0 0 2 2 2 0 AAA-like domain MeaB PF03308.16 KFM23419.1 - 0.025 13.6 3.9 0.75 8.7 0.3 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 KFM23419.1 - 0.043 14.0 0.2 5.9 7.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 KFM23419.1 - 0.052 13.6 3.8 5 7.2 0.7 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Rad17 PF03215.15 KFM23419.1 - 0.059 13.3 1.5 11 5.9 0.0 2.6 3 0 0 3 3 3 0 Rad17 P-loop domain AAA_27 PF13514.6 KFM23419.1 - 0.13 11.8 0.7 16 5.0 0.1 2.2 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 KFM23419.1 - 0.19 11.4 0.2 15 5.2 0.0 2.6 2 0 0 2 2 2 0 Thymidylate kinase FeoB_associated PF12669.7 KFM23419.1 - 0.33 11.4 4.5 1.5 9.2 4.5 2.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein T2SSE PF00437.20 KFM23419.1 - 0.6 9.1 2.7 9.8 5.1 0.2 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein ABC2_membrane_2 PF12679.7 KFM23419.1 - 2 7.6 39.5 6.9 5.9 17.2 3.7 3 1 0 3 3 3 0 ABC-2 family transporter protein AAA_28 PF13521.6 KFM23419.1 - 2.6 8.2 4.5 25 5.1 0.3 2.4 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 KFM23419.1 - 5.2 7.1 6.2 20 5.2 0.6 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain ABC_tran PF00005.27 KFM23420.1 - 5.8e-22 78.7 0.0 9e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 KFM23420.1 - 3.2e-20 72.6 23.6 6.4e-20 71.5 23.6 1.5 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 KFM23420.1 - 1.5e-10 41.4 0.1 1.7e-06 28.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KFM23420.1 - 8e-05 23.2 0.2 0.00013 22.6 0.2 1.2 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFM23420.1 - 0.03 14.1 0.0 0.18 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KFM23420.1 - 0.033 13.9 0.0 0.067 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 KFM23420.1 - 0.069 12.8 0.0 1.5 8.5 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain SRP54 PF00448.22 KFM23420.1 - 0.24 11.0 0.1 0.38 10.3 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Coprogen_oxidas PF01218.18 KFM23422.1 - 1.8e-130 434.0 0.0 2.1e-130 433.8 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Flavokinase PF01687.17 KFM23423.1 - 1.2e-29 102.8 0.0 2.1e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 Riboflavin kinase HAD_2 PF13419.6 KFM23423.1 - 3.4e-26 92.4 0.0 4.3e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFM23423.1 - 3e-17 63.6 0.0 7.1e-17 62.4 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFM23423.1 - 4.6e-08 33.7 0.0 7.8e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFM23423.1 - 2.1e-07 30.9 0.1 4.8e-07 29.8 0.1 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 KFM23423.1 - 0.0038 17.3 0.0 1.1 9.4 0.0 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase UDPGT PF00201.18 KFM23425.1 - 1.5e-31 109.8 0.0 1.6e-30 106.4 0.0 2.0 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KFM23425.1 - 0.0058 16.6 0.0 0.0088 16.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.6 KFM23425.1 - 0.093 12.0 0.0 0.25 10.6 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase family 1 Pkinase PF00069.25 KFM23426.1 - 1.5e-44 152.4 0.0 1.7e-32 112.9 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFM23426.1 - 1.3e-23 83.7 0.0 8.6e-17 61.3 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KFM23426.1 - 0.005 16.2 0.2 0.6 9.4 0.1 2.2 1 1 1 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KFM23426.1 - 0.013 14.3 0.0 0.018 13.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 KFM23426.1 - 0.21 11.2 0.0 0.44 10.1 0.0 1.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pox_ser-thr_kin PF05445.11 KFM23426.1 - 0.31 10.0 0.0 0.43 9.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PAP2 PF01569.21 KFM23428.1 - 2.5e-22 79.1 2.1 4.7e-22 78.2 2.1 1.4 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 KFM23428.1 - 0.0053 16.5 5.5 0.033 13.9 5.4 2.3 1 1 0 1 1 1 1 PAP2 superfamily Chloroa_b-bind PF00504.21 KFM23429.1 - 7.6e-06 26.5 0.4 0.00071 20.1 0.1 2.0 1 1 1 2 2 2 2 Chlorophyll A-B binding protein RPE65 PF03055.15 KFM23430.1 - 7.8e-96 322.1 0.0 1.1e-95 321.6 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Aminotran_5 PF00266.19 KFM23430.1 - 7.6e-33 114.0 0.0 2.5e-23 82.7 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class-V DUF3717 PF12512.8 KFM23430.1 - 0.15 11.9 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3717) LRR_4 PF12799.7 KFM23431.1 - 2.4e-30 104.1 12.6 1.9e-07 31.3 3.2 5.5 4 2 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFM23431.1 - 1.2e-21 76.2 33.3 8.9e-09 35.0 5.0 5.6 2 1 3 6 6 6 6 Leucine rich repeat LRR_9 PF14580.6 KFM23431.1 - 3.3e-20 72.3 0.0 4.5e-12 45.8 0.0 3.1 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 KFM23431.1 - 1e-05 25.4 10.5 2.8 8.8 0.1 7.2 8 0 0 8 8 8 2 Leucine Rich Repeat LRR_6 PF13516.6 KFM23431.1 - 5e-05 23.0 14.3 2.8 8.2 0.9 7.6 8 0 0 8 8 8 2 Leucine Rich repeat Exo70 PF03081.15 KFM23432.1 - 2.6e-17 62.9 0.0 4e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Str_synth PF03088.16 KFM23433.1 - 2.9e-16 59.3 0.0 2.1e-15 56.6 0.0 2.5 3 0 0 3 3 3 1 Strictosidine synthase SGL PF08450.12 KFM23433.1 - 7.5e-10 38.8 0.0 2e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 KFM23433.1 - 2.7e-05 24.0 1.9 1.5 9.0 0.0 4.8 5 0 0 5 5 5 2 NHL repeat Arylesterase PF01731.20 KFM23433.1 - 0.11 12.7 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Arylesterase Btz PF09405.10 KFM23434.1 - 4.7e-05 23.6 2.3 4.7e-05 23.6 2.3 2.8 2 1 1 3 3 3 1 CASC3/Barentsz eIF4AIII binding Response_reg PF00072.24 KFM23436.1 - 8.2e-22 77.5 0.0 1.6e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain WD40 PF00400.32 KFM23436.1 - 1.3e-11 44.9 0.5 0.13 13.1 0.1 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat Molybdopterin PF00384.22 KFM23437.1 - 1.1e-40 140.0 0.0 1.3e-26 93.6 0.0 3.2 1 1 2 3 3 3 3 Molybdopterin oxidoreductase Fer2_4 PF13510.6 KFM23437.1 - 3.9e-21 74.9 0.1 8.3e-21 73.8 0.1 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 KFM23437.1 - 5.6e-17 61.0 0.1 5.6e-17 61.0 0.1 1.8 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region NADH_dhqG_C PF09326.11 KFM23437.1 - 2.8e-14 53.5 0.0 7.2e-14 52.2 0.0 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2 PF00111.27 KFM23437.1 - 2.5e-09 37.0 0.4 2.5e-09 37.0 0.4 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DUF3772 PF12607.8 KFM23437.1 - 0.033 13.9 0.4 0.088 12.6 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3772) Fer4_19 PF06902.11 KFM23437.1 - 0.068 13.3 0.9 0.41 10.8 0.9 2.2 1 1 0 1 1 1 0 Divergent 4Fe-4S mono-cluster Fer4 PF00037.27 KFM23437.1 - 0.14 12.0 1.3 4.8 7.2 0.4 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain EF_TS PF00889.19 KFM23439.1 - 4e-32 111.5 1.5 8.8e-32 110.4 1.3 1.8 1 1 0 1 1 1 1 Elongation factor TS Arm PF00514.23 KFM23440.1 - 1.1e-84 276.1 16.0 2.6e-12 46.3 0.0 8.9 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KFM23440.1 - 3.6e-20 72.1 8.9 1.5e-08 34.9 0.2 6.3 5 3 1 6 6 6 3 HEAT-like repeat Arm_3 PF16186.5 KFM23440.1 - 4e-20 71.1 0.1 7.3e-20 70.3 0.1 1.4 1 0 0 1 1 1 1 Atypical Arm repeat IBB PF01749.20 KFM23440.1 - 9.6e-20 70.8 1.0 2e-19 69.8 1.0 1.5 1 0 0 1 1 1 1 Importin beta binding domain HEAT_2 PF13646.6 KFM23440.1 - 2.1e-12 47.2 7.1 4.1e-05 23.9 0.3 5.5 3 1 3 6 6 6 4 HEAT repeats HEAT PF02985.22 KFM23440.1 - 6.2e-10 38.5 3.1 0.00043 20.3 0.0 7.2 8 0 0 8 8 7 1 HEAT repeat Arm_2 PF04826.13 KFM23440.1 - 2.2e-09 37.1 0.0 0.001 18.6 0.1 3.3 3 0 0 3 3 3 3 Armadillo-like V-ATPase_H_C PF11698.8 KFM23440.1 - 0.0023 18.0 0.0 12 6.0 0.0 3.9 3 2 1 4 4 4 1 V-ATPase subunit H NopRA1 PF16201.5 KFM23440.1 - 0.027 14.1 0.0 14 5.2 0.0 3.8 3 1 1 4 4 4 0 Nucleolar pre-ribosomal-associated protein 1 RICTOR_V PF14668.6 KFM23440.1 - 0.04 14.2 2.3 13 6.1 0.0 4.1 4 1 1 5 5 5 0 Rapamycin-insensitive companion of mTOR, domain 5 SEN1_N PF12726.7 KFM23440.1 - 0.07 11.3 0.1 2.5 6.2 0.0 2.9 3 1 1 4 4 4 0 SEN1 N terminal HEAT_PBS PF03130.16 KFM23440.1 - 0.31 11.8 0.1 0.31 11.8 0.1 5.1 6 1 0 6 6 4 0 PBS lyase HEAT-like repeat Pyr_redox_2 PF07992.14 KFM23441.1 - 4.2e-10 39.4 0.0 1.9e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFM23441.1 - 6.1e-05 23.2 0.0 0.00016 21.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KFM23441.1 - 0.00085 19.3 0.1 0.0042 17.1 0.0 2.1 2 1 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.14 KFM23441.1 - 0.21 10.3 0.0 0.46 9.1 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein WD40 PF00400.32 KFM23442.1 - 3e-15 56.4 9.7 1.3e-07 32.2 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM23442.1 - 0.00034 20.8 0.0 0.79 10.1 0.0 3.5 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Complex1_LYR PF05347.15 KFM23443.1 - 0.0061 16.6 0.1 0.009 16.0 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Proteasome PF00227.26 KFM23444.1 - 9.2e-36 123.1 0.1 1.4e-35 122.6 0.0 1.3 2 0 0 2 2 2 1 Proteasome subunit bMG5 PF17972.1 KFM23444.1 - 0.049 14.0 0.3 1.1 9.7 0.0 2.1 2 0 0 2 2 2 0 Bacterial Alpha-2-macroglobulin MG5 domain Citrate_synt PF00285.21 KFM23445.1 - 3.9e-130 434.1 0.0 4.7e-130 433.9 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain TPR_14 PF13428.6 KFM23447.1 - 2.5e-19 68.3 40.3 0.0059 17.3 0.2 11.9 3 3 9 12 12 12 8 Tetratricopeptide repeat Suf PF05843.14 KFM23447.1 - 8.7e-19 68.6 5.4 2.7e-07 30.9 0.9 6.5 1 1 4 6 6 6 4 Suppressor of forked protein (Suf) HAT PF02184.16 KFM23447.1 - 5.1e-14 51.9 82.2 3e-10 39.9 0.2 14.7 14 2 0 14 14 14 4 HAT (Half-A-TPR) repeat TPR_19 PF14559.6 KFM23447.1 - 3.7e-13 49.8 0.6 0.013 15.9 0.0 6.9 4 2 4 8 8 8 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFM23447.1 - 8.2e-10 38.0 11.4 0.014 15.5 0.1 8.4 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFM23447.1 - 6e-07 30.0 30.7 0.047 14.4 0.2 7.6 7 1 1 8 8 8 3 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KFM23447.1 - 9.1e-07 28.9 15.6 0.42 10.6 0.4 6.4 4 3 2 6 6 6 3 Mad3/BUB1 homology region 1 TPR_17 PF13431.6 KFM23447.1 - 2e-06 27.8 0.3 8.3 7.0 0.0 7.0 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 KFM23447.1 - 6.9e-06 25.5 19.8 0.16 11.2 0.1 6.1 1 1 5 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 KFM23447.1 - 7e-06 25.9 0.0 0.36 11.2 0.0 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFM23447.1 - 2.1e-05 24.7 10.2 0.61 10.4 0.0 6.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFM23447.1 - 0.022 14.6 17.5 1.1 9.3 0.5 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFM23447.1 - 0.031 14.9 23.1 9.2 7.2 0.5 9.3 10 1 1 11 11 10 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFM23447.1 - 0.055 13.3 1.0 2.4 8.1 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFM23447.1 - 0.061 13.4 8.6 26 5.1 0.1 5.9 6 1 1 7 7 7 0 Tetratricopeptide repeat U3_assoc_6 PF08640.11 KFM23447.1 - 0.12 12.5 10.8 32 4.7 0.1 6.4 5 2 1 6 6 6 0 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.10 KFM23447.1 - 0.21 10.7 15.2 4.2 6.4 3.4 5.5 2 2 2 4 4 4 0 NRDE-2, necessary for RNA interference TPR_5 PF12688.7 KFM23447.1 - 3.6 7.8 7.5 24 5.2 0.0 3.3 3 1 0 3 3 3 0 Tetratrico peptide repeat Hydrolase_4 PF12146.8 KFM23448.1 - 9.4e-11 41.4 0.6 1.9e-10 40.5 0.1 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFM23448.1 - 3.2e-10 40.1 0.1 5.7e-10 39.3 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFM23448.1 - 6.9e-08 33.4 17.2 6.9e-08 33.4 17.2 2.9 2 1 1 3 3 3 1 Alpha/beta hydrolase family Thioesterase PF00975.20 KFM23448.1 - 0.00047 20.4 0.0 0.0052 16.9 0.0 2.1 2 0 0 2 2 2 1 Thioesterase domain PseudoU_synth_2 PF00849.22 KFM23449.1 - 4.3e-25 88.7 0.0 9.5e-25 87.5 0.0 1.6 1 0 0 1 1 1 1 RNA pseudouridylate synthase CsoS2_M PF12288.8 KFM23449.1 - 0.057 12.8 3.6 0.088 12.2 3.6 1.2 1 0 0 1 1 1 0 Carboxysome shell peptide mid-region Adeno_VII PF03228.14 KFM23449.1 - 0.54 10.9 4.5 2.6 8.7 0.0 3.1 3 0 0 3 3 3 0 Adenoviral core protein VII RCC1 PF00415.18 KFM23450.1 - 1.4e-46 156.8 12.0 1.1e-09 38.7 0.1 8.0 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat GDI PF00996.18 KFM23450.1 - 2.9e-21 75.5 0.0 6e-21 74.5 0.0 1.4 1 1 0 1 1 1 1 GDP dissociation inhibitor ABC_tran PF00005.27 KFM23450.1 - 2.1e-17 63.9 0.0 3.6e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter RCC1_2 PF13540.6 KFM23450.1 - 1.1e-14 53.8 29.8 6.2e-06 25.9 0.5 7.0 7 1 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat SMC_N PF02463.19 KFM23450.1 - 0.00035 20.1 0.5 0.81 9.1 0.2 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFM23450.1 - 0.00073 19.4 0.0 0.68 9.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system CPT PF07931.12 KFM23450.1 - 0.0017 18.2 0.1 0.045 13.6 0.0 2.5 3 0 0 3 3 3 1 Chloramphenicol phosphotransferase-like protein AAA_29 PF13555.6 KFM23450.1 - 0.005 16.6 1.6 0.011 15.4 0.1 2.4 3 0 0 3 3 3 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFM23450.1 - 0.24 11.3 0.1 0.44 10.4 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_13 PF13166.6 KFM23450.1 - 0.3 9.7 0.0 0.44 9.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain TauD PF02668.16 KFM23451.1 - 6.7e-18 65.4 0.3 3.4e-13 50.0 0.1 2.2 2 0 0 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KFM23451.1 - 0.0059 15.8 0.0 0.0088 15.2 0.0 1.2 1 0 0 1 1 1 1 CsiD TilS PF09179.11 KFM23451.1 - 0.089 13.3 3.8 1.4 9.5 0.1 2.9 3 0 0 3 3 3 0 TilS substrate binding domain Pkinase_Tyr PF07714.17 KFM23452.1 - 2.6e-52 177.7 0.0 3.9e-52 177.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM23452.1 - 1.5e-41 142.5 0.0 2.1e-41 142.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 KFM23452.1 - 2.9e-05 23.2 0.0 4.7e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain LRRNT_2 PF08263.12 KFM23452.1 - 6.4e-05 23.2 0.2 6.4e-05 23.2 0.2 2.0 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain Kinase-like PF14531.6 KFM23452.1 - 0.00048 19.5 0.1 0.0011 18.4 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KFM23452.1 - 0.0021 18.0 0.1 0.0061 16.5 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family LRR_4 PF12799.7 KFM23452.1 - 0.015 15.7 2.0 0.052 14.0 0.6 2.4 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFM23452.1 - 0.1 12.4 3.7 0.62 9.9 3.5 2.2 1 1 0 1 1 1 0 Leucine rich repeat Lipase_3 PF01764.25 KFM23453.1 - 9.9e-11 41.7 0.0 1.4e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KFM23453.1 - 5e-05 24.0 9.2 7.1e-05 23.5 9.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family B12-binding PF02310.19 KFM23453.1 - 0.0034 17.4 0.0 0.0065 16.5 0.0 1.5 1 0 0 1 1 1 1 B12 binding domain Hydrolase_4 PF12146.8 KFM23453.1 - 0.0056 16.0 0.1 0.0076 15.5 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KFM23453.1 - 0.0076 16.0 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 KFM23453.1 - 0.046 13.8 0.1 0.059 13.5 0.1 1.2 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_3 PF07859.13 KFM23453.1 - 0.079 12.8 0.1 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KFM23453.1 - 0.11 12.1 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KFM23453.1 - 0.12 12.2 0.3 0.17 11.7 0.3 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Esterase PF00756.20 KFM23453.1 - 0.24 11.0 0.4 0.39 10.3 0.4 1.3 1 0 0 1 1 1 0 Putative esterase DUF2974 PF11187.8 KFM23453.1 - 0.29 10.6 0.0 0.37 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) FA_hydroxylase PF04116.13 KFM23455.1 - 3.6e-20 72.7 19.2 3.6e-20 72.7 19.2 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Ion_trans PF00520.31 KFM23455.1 - 0.022 14.0 4.0 0.04 13.1 4.0 1.3 1 0 0 1 1 1 0 Ion transport protein TPPK_C PF12555.8 KFM23455.1 - 0.043 13.9 1.0 0.11 12.6 1.0 1.7 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal CRAL_TRIO PF00650.20 KFM23456.1 - 1.7e-32 112.4 0.0 2.1e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFM23456.1 - 0.0066 16.6 0.0 0.0085 16.3 0.0 1.3 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain VQ PF05678.14 KFM23456.1 - 0.06 12.8 0.1 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 VQ motif Glycolytic PF00274.19 KFM23457.1 - 1.2e-156 520.9 0.0 1.6e-156 520.4 0.0 1.2 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Proteasome PF00227.26 KFM23458.1 - 1.4e-58 197.6 0.0 1.7e-58 197.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KFM23458.1 - 3.5e-13 49.0 0.0 6.8e-13 48.0 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature LRR_4 PF12799.7 KFM23460.1 - 1.8e-18 66.3 7.0 0.00035 20.9 0.2 6.4 5 2 2 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFM23460.1 - 9.2e-14 51.0 16.2 7.8e-08 32.0 0.2 6.2 5 3 0 6 6 6 3 Leucine rich repeat LRR_1 PF00560.33 KFM23460.1 - 4.4e-07 29.5 0.9 33 5.6 0.0 7.0 9 0 0 9 9 9 0 Leucine Rich Repeat PRIMA1 PF16101.5 KFM23460.1 - 0.16 12.0 0.8 0.32 11.0 0.8 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF4307 PF14155.6 KFM23460.1 - 0.61 9.9 2.6 3.7 7.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) LRR_6 PF13516.6 KFM23460.1 - 4.4 7.6 15.0 8.3 6.7 0.1 6.3 8 0 0 8 8 8 0 Leucine Rich repeat UPF0113_N PF17833.1 KFM23462.1 - 9.1e-27 93.5 0.0 1.3e-26 92.9 0.0 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 KFM23462.1 - 5.2e-25 87.5 0.0 1.1e-24 86.5 0.0 1.5 1 0 0 1 1 1 1 UPF0113 PUA domain PSII_BNR PF14870.6 KFM23463.1 - 4.4e-121 403.8 2.1 5.5e-121 403.5 2.1 1.1 1 0 0 1 1 1 1 Photosynthesis system II assembly factor YCF48 Sortilin-Vps10 PF15902.5 KFM23463.1 - 3.3e-09 36.0 0.0 0.0066 15.3 0.0 3.3 3 0 0 3 3 3 3 Sortilin, neurotensin receptor 3, BNR PF02012.20 KFM23463.1 - 8.6e-09 34.1 11.1 0.3 11.2 0.2 5.8 5 0 0 5 5 5 4 BNR/Asp-box repeat Porphobil_deam PF01379.20 KFM23465.1 - 2.4e-77 259.1 0.0 3.2e-77 258.6 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 KFM23465.1 - 1.4e-15 57.4 0.1 2.4e-15 56.7 0.1 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain SBP_bac_3 PF00497.20 KFM23465.1 - 0.13 11.7 0.0 0.4 10.1 0.0 1.7 1 1 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 Amidase PF01425.21 KFM23466.1 - 8.4e-152 506.2 0.6 1.1e-151 505.9 0.6 1.1 1 0 0 1 1 1 1 Amidase CRAL_TRIO PF00650.20 KFM23466.1 - 6.7e-36 123.4 0.0 9.6e-36 122.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFM23466.1 - 0.0043 17.2 0.0 0.0081 16.3 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFM23466.1 - 0.044 14.0 0.3 0.13 12.5 0.3 1.8 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain UPF0220 PF05255.11 KFM23467.1 - 2e-23 82.8 0.9 2.4e-23 82.5 0.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) PRP38 PF03371.15 KFM23468.1 - 1.3e-47 161.9 0.0 1.8e-47 161.4 0.0 1.1 1 0 0 1 1 1 1 PRP38 family PRP38_assoc PF12871.7 KFM23468.1 - 0.034 14.8 6.5 0.055 14.1 6.5 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Pkinase PF00069.25 KFM23470.1 - 5.4e-30 104.7 0.0 7.5e-19 68.1 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFM23470.1 - 6.4e-09 35.5 0.0 0.00033 20.0 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Abhydrolase_2 PF02230.16 KFM23472.1 - 2.6e-07 30.7 0.0 6.7e-06 26.1 0.0 2.1 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase TPR_2 PF07719.17 KFM23472.1 - 0.00015 21.6 0.2 0.18 12.0 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFM23472.1 - 0.001 19.1 0.0 0.32 11.3 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFM23472.1 - 0.0031 18.2 5.7 0.031 15.1 0.6 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFM23472.1 - 0.0037 17.0 0.0 1.4 8.8 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFM23472.1 - 0.0079 16.8 6.1 0.088 13.5 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFM23472.1 - 0.011 16.1 0.2 0.025 14.8 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat A_amylase_inhib PF01356.19 KFM23472.1 - 0.025 14.6 0.0 0.055 13.5 0.0 1.5 1 0 0 1 1 1 0 Alpha amylase inhibitor TPR_19 PF14559.6 KFM23472.1 - 0.23 12.0 4.4 1.6 9.3 0.1 2.2 1 1 0 1 1 1 0 Tetratricopeptide repeat AMP-binding PF00501.28 KFM23473.1 - 1.3e-53 182.2 0.4 5.1e-47 160.4 0.2 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 KFM23473.1 - 9.4e-14 52.2 0.0 2.2e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SAND PF01342.21 KFM23475.1 - 0.0001 21.9 0.0 0.00018 21.1 0.0 1.4 1 0 0 1 1 1 1 SAND domain OrfB_Zn_ribbon PF07282.11 KFM23475.1 - 0.0025 17.7 5.2 0.012 15.5 5.2 2.2 1 1 0 1 1 1 1 Putative transposase DNA-binding domain DUF2152 PF10222.9 KFM23475.1 - 0.2 9.9 0.3 0.28 9.5 0.3 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2152) OrfB_Zn_ribbon PF07282.11 KFM23477.1 - 3e-05 23.9 6.1 0.00013 21.8 6.1 1.9 1 1 0 1 1 1 1 Putative transposase DNA-binding domain DUF2152 PF10222.9 KFM23477.1 - 0.033 12.5 0.2 0.04 12.3 0.2 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2152) Pkinase PF00069.25 KFM23479.1 - 1.8e-69 234.0 0.0 2.2e-69 233.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM23479.1 - 7.7e-41 140.1 0.0 9.9e-41 139.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM23479.1 - 0.0002 20.8 0.0 0.0026 17.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like SspN PF08177.11 KFM23479.1 - 0.0041 17.0 0.0 0.012 15.6 0.0 1.7 1 1 0 1 1 1 1 Small acid-soluble spore protein N family FTA2 PF13095.6 KFM23479.1 - 0.02 14.5 0.1 5.2 6.6 0.0 2.1 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 KFM23479.1 - 0.25 10.4 0.0 0.39 9.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Myb_DNA-bind_6 PF13921.6 KFM23480.1 - 2.3e-07 31.0 1.8 0.0099 16.1 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KFM23480.1 - 0.00058 20.0 9.0 0.0061 16.7 0.5 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Forkhead PF00250.18 KFM23480.1 - 0.0021 18.2 0.0 0.0069 16.6 0.0 1.9 1 1 0 1 1 1 1 Forkhead domain UPF0564 PF10595.9 KFM23480.1 - 0.045 12.8 1.0 0.067 12.2 1.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 Atg29_N PF18388.1 KFM23480.1 - 0.048 13.5 3.8 0.69 9.8 0.1 2.6 2 1 0 2 2 2 0 Atg29 N-terminal domain Ribosomal_L36e PF01158.18 KFM23481.1 - 1.2e-39 134.5 11.8 1.3e-39 134.3 11.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e DUF2207 PF09972.9 KFM23481.1 - 0.12 11.1 0.2 0.12 11.2 0.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MATH PF00917.26 KFM23482.1 - 1.3e-24 86.5 0.1 1.9e-24 86.0 0.1 1.2 1 0 0 1 1 1 1 MATH domain Rib_5-P_isom_A PF06026.14 KFM23483.1 - 5.4e-62 208.4 0.2 7.9e-62 207.9 0.0 1.3 2 0 0 2 2 2 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 KFM23483.1 - 0.00047 20.1 0.0 0.0069 16.3 0.0 2.2 2 0 0 2 2 2 1 DeoR C terminal sensor domain GCFC PF07842.12 KFM23484.1 - 2.9e-42 145.2 0.9 4.2e-42 144.7 0.9 1.3 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.8 KFM23484.1 - 1.5e-18 67.1 8.1 2.9e-18 66.2 8.1 1.4 1 0 0 1 1 1 1 Tuftelin interacting protein N terminal G-patch PF01585.23 KFM23484.1 - 6.1e-10 38.8 9.5 2.9e-09 36.7 9.5 2.2 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KFM23484.1 - 7.2e-06 26.0 6.5 7.2e-06 26.0 6.5 3.0 3 0 0 3 3 3 1 G-patch domain PDEase_I PF00233.19 KFM23485.1 - 7.9e-62 209.1 0.0 1e-61 208.7 0.0 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 KFM23485.1 - 0.058 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 HD domain cNMP_binding PF00027.29 KFM23486.1 - 8e-10 38.7 0.0 1.4e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Popeye PF04831.13 KFM23486.1 - 2.8e-05 24.3 0.2 4.8e-05 23.5 0.2 1.4 1 0 0 1 1 1 1 Popeye protein conserved region dCMP_cyt_deam_1 PF00383.23 KFM23487.1 - 3.7e-21 74.9 0.0 5e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KFM23487.1 - 3.8e-16 59.1 0.0 4.6e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase Inv-AAD PF18785.1 KFM23487.1 - 0.0096 15.8 0.3 0.025 14.4 0.3 1.8 1 1 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase SNAD4 PF18750.1 KFM23487.1 - 0.045 13.9 0.0 0.082 13.0 0.0 1.4 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 Pyr_redox_2 PF07992.14 KFM23488.1 - 1.1e-49 169.3 0.5 1.2e-49 169.1 0.5 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFM23488.1 - 2e-22 79.9 0.2 1.6e-18 67.0 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFM23488.1 - 1.3e-19 70.5 0.8 4.7e-18 65.5 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFM23488.1 - 4.4e-06 25.7 0.9 0.081 11.6 0.2 3.4 3 0 0 3 3 3 2 HI0933-like protein FAD_binding_3 PF01494.19 KFM23488.1 - 4.8e-06 26.1 0.1 0.045 13.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.22 KFM23488.1 - 4.6e-05 22.7 6.6 0.069 12.2 0.5 4.0 3 2 0 4 4 4 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KFM23488.1 - 5.1e-05 22.5 0.5 0.041 13.0 0.1 3.7 4 0 0 4 4 4 1 FAD binding domain Thi4 PF01946.17 KFM23488.1 - 0.00038 19.8 0.1 0.078 12.2 0.0 3.1 4 1 0 4 4 4 1 Thi4 family NAD_binding_8 PF13450.6 KFM23488.1 - 0.00082 19.6 0.1 0.39 11.0 0.1 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KFM23488.1 - 0.0012 18.0 0.0 0.091 11.9 0.0 2.9 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 KFM23488.1 - 0.0017 18.8 0.1 0.11 12.9 0.0 2.6 2 2 0 2 2 2 1 Putative NAD(P)-binding FAD_oxidored PF12831.7 KFM23488.1 - 0.0026 17.2 0.0 0.021 14.2 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase F420_oxidored PF03807.17 KFM23488.1 - 0.0034 17.9 0.5 0.32 11.6 0.0 2.9 3 1 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.24 KFM23488.1 - 0.0086 15.7 2.3 1.9 8.0 0.1 3.2 3 1 1 4 4 4 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KFM23488.1 - 0.017 14.5 0.2 3.2 7.0 0.1 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 KFM23488.1 - 0.093 12.7 1.2 2.7 8.0 0.0 2.8 3 0 0 3 3 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 KFM23488.1 - 0.11 12.4 0.0 7.7 6.4 0.1 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KFM23488.1 - 0.13 12.3 0.5 5.6 7.0 0.0 3.1 4 0 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.14 KFM23488.1 - 0.15 10.9 0.6 1.6 7.4 0.1 2.6 3 0 0 3 3 3 0 Tryptophan halogenase PsbP PF01789.16 KFM23490.1 - 5e-31 108.0 0.0 5.8e-31 107.7 0.0 1.0 1 0 0 1 1 1 1 PsbP WW PF00397.26 KFM23490.1 - 0.87 9.7 2.9 25 5.1 0.3 2.5 2 0 0 2 2 2 0 WW domain DUF563 PF04577.14 KFM23491.1 - 3.7e-13 50.1 0.0 4.9e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF563) TBCA PF02970.16 KFM23492.1 - 5.8e-22 77.8 2.0 6.8e-22 77.6 2.0 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A Helo_like_N PF17111.5 KFM23492.1 - 0.0046 16.4 0.6 0.023 14.1 0.1 1.9 1 1 1 2 2 2 1 Fungal N-terminal domain of STAND proteins CP12 PF02672.15 KFM23492.1 - 0.009 16.7 1.1 0.066 14.0 0.4 2.1 2 0 0 2 2 2 1 CP12 domain Flg_hook PF02120.16 KFM23492.1 - 0.023 14.6 0.4 0.053 13.4 0.4 1.7 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK Spc7 PF08317.11 KFM23492.1 - 0.027 13.4 1.7 0.036 13.0 1.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4404 PF14357.6 KFM23492.1 - 0.046 14.3 4.5 0.3 11.7 0.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) RMI1_C PF16099.5 KFM23492.1 - 0.072 12.9 0.3 0.18 11.6 0.3 1.7 1 1 0 1 1 1 0 Recq-mediated genome instability protein 1, C-terminal OB-fold Seryl_tRNA_N PF02403.22 KFM23492.1 - 0.12 12.7 3.0 1.1 9.5 3.0 2.1 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Pkinase PF00069.25 KFM23493.1 - 1.8e-28 99.6 0.0 2.6e-28 99.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM23493.1 - 1.6e-05 24.3 0.0 3.6e-05 23.2 0.0 1.6 1 1 1 2 2 2 1 Protein tyrosine kinase DUF1192 PF06698.11 KFM23493.1 - 0.017 15.2 0.4 0.039 14.0 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Pkinase PF00069.25 KFM23494.1 - 6.5e-31 107.7 1.5 7.3e-31 107.5 1.5 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM23494.1 - 3.2e-18 65.9 0.5 3.9e-18 65.7 0.5 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase FeoB_N PF02421.18 KFM23494.1 - 0.049 13.2 0.5 0.41 10.2 0.8 1.8 1 1 1 2 2 2 0 Ferrous iron transport protein B ACOX PF01756.19 KFM23495.1 - 8.4e-43 146.0 0.0 3.1e-42 144.2 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 KFM23495.1 - 5e-19 69.1 0.1 7.9e-19 68.4 0.1 1.3 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 KFM23495.1 - 1.4e-14 54.1 0.0 2.9e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KFM23495.1 - 0.00064 20.4 0.0 0.002 18.8 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 KFM23495.1 - 0.0073 16.5 0.0 0.0073 16.5 0.0 2.5 2 2 1 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain RNA_pol_Rpb2_6 PF00562.28 KFM23496.1 - 3.4e-107 358.9 0.1 6.5e-103 344.8 0.0 2.2 1 1 1 2 2 2 2 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KFM23496.1 - 3.1e-66 222.7 0.0 4.5e-66 222.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KFM23496.1 - 2.7e-48 164.1 0.0 5.2e-48 163.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KFM23496.1 - 7.9e-34 115.9 0.1 2.1e-33 114.6 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 KFM23496.1 - 1.5e-26 92.3 0.0 3.9e-26 91.0 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 KFM23496.1 - 8.5e-21 74.0 0.4 1.9e-20 72.9 0.4 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 KFM23496.1 - 1.5e-18 67.1 2.9 3.6e-18 65.9 2.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 Zn_Tnp_IS1595 PF12760.7 KFM23496.1 - 0.03 14.3 0.9 0.29 11.2 0.5 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain MeaB PF03308.16 KFM23497.1 - 8.6e-92 306.9 0.4 1.1e-91 306.6 0.4 1.1 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 KFM23497.1 - 2e-05 24.2 0.1 0.00032 20.3 0.1 2.3 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.17 KFM23497.1 - 0.0021 17.8 0.0 0.0062 16.3 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_30 PF13604.6 KFM23497.1 - 0.0034 17.1 0.6 0.0034 17.1 0.6 2.5 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.17 KFM23497.1 - 0.0041 16.9 0.0 0.0093 15.8 0.1 1.6 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 KFM23497.1 - 0.0047 16.6 0.1 0.016 14.9 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KFM23497.1 - 0.0074 16.4 0.0 0.017 15.2 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KFM23497.1 - 0.011 16.3 0.1 0.023 15.2 0.1 1.5 1 0 0 1 1 1 0 ABC transporter CbiA PF01656.23 KFM23497.1 - 0.014 15.4 0.0 0.043 13.9 0.0 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain FtsK_SpoIIIE PF01580.18 KFM23497.1 - 0.017 14.5 1.4 0.75 9.1 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.6 KFM23497.1 - 0.02 15.4 0.0 0.037 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain ParA PF10609.9 KFM23497.1 - 0.026 14.0 0.6 0.41 10.0 0.3 2.1 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase AAA_24 PF13479.6 KFM23497.1 - 0.036 13.8 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KFM23497.1 - 0.045 14.3 0.1 0.094 13.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 KFM23497.1 - 0.045 13.3 0.0 2.9 7.4 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFM23497.1 - 0.055 13.4 0.0 2 8.3 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 KFM23497.1 - 0.06 13.6 0.1 0.69 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KFM23497.1 - 0.13 12.6 6.2 0.16 12.3 0.2 2.5 2 2 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 KFM23497.1 - 0.13 11.5 0.1 1.7 7.9 0.1 2.1 2 0 0 2 2 2 0 Zeta toxin NTPase_1 PF03266.15 KFM23497.1 - 0.19 11.6 0.0 0.38 10.6 0.0 1.5 1 0 0 1 1 1 0 NTPase CLP1_P PF16575.5 KFM23497.1 - 0.2 11.4 0.0 0.38 10.5 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_28 PF13521.6 KFM23497.1 - 0.22 11.7 1.7 0.3 11.3 0.0 2.0 2 1 0 2 2 2 0 AAA domain adh_short_C2 PF13561.6 KFM23498.1 - 3.8e-30 105.2 0.4 1.2e-29 103.5 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFM23498.1 - 4.3e-29 101.4 0.0 9.4e-28 97.0 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N PF00107.26 KFM23498.1 - 1.2e-22 80.3 0.0 2.3e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFM23498.1 - 6.4e-16 59.6 0.0 1.4e-15 58.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PsbP PF01789.16 KFM23498.1 - 6.3e-09 36.2 0.0 1.3e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 PsbP ADH_N PF08240.12 KFM23498.1 - 7.3e-08 32.3 0.0 3.2e-07 30.2 0.0 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KFM23498.1 - 0.025 14.5 0.0 0.061 13.2 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Endonuclease_NS PF01223.23 KFM23499.1 - 2.6e-54 184.4 0.0 3.4e-54 184.1 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Cyclin_N PF00134.23 KFM23500.1 - 7.9e-12 45.0 0.2 1.2e-11 44.4 0.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 KFM23500.1 - 1e-05 25.5 0.0 1.8e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Transcription factor TFIIB repeat RB_B PF01857.20 KFM23500.1 - 0.2 11.7 0.2 0.42 10.6 0.2 1.5 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain Acetyltransf_13 PF13880.6 KFM23501.1 - 2.5e-15 56.2 0.0 4e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_1 PF00583.25 KFM23501.1 - 9e-05 22.7 0.0 0.00011 22.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family PanZ PF12568.8 KFM23501.1 - 0.0027 17.4 0.1 0.006 16.3 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_7 PF13508.7 KFM23501.1 - 0.0034 17.8 0.0 0.0059 17.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain dUTPase PF00692.19 KFM23502.1 - 2.3e-42 143.7 0.0 2.8e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 dUTPase ABC1 PF03109.16 KFM23503.1 - 1.4e-29 102.7 0.0 2.8e-29 101.7 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 KFM23503.1 - 1.5e-06 28.3 0.4 9.8e-06 25.7 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 KFM23503.1 - 0.0096 15.3 0.0 0.12 11.7 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain DUF1156 PF06634.12 KFM23503.1 - 0.014 15.5 0.0 0.033 14.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1156) Atg14 PF10186.9 KFM23504.1 - 0.018 14.1 11.1 0.024 13.7 11.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4201 PF13870.6 KFM23504.1 - 0.097 12.4 7.9 0.61 9.8 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) MRP-S26 PF14943.6 KFM23504.1 - 0.19 11.6 5.6 0.27 11.1 5.6 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 UCH PF00443.29 KFM23505.1 - 4.6e-43 147.6 0.0 6.6e-43 147.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 KFM23505.1 - 3.2e-18 65.2 0.0 6.3e-18 64.3 0.0 1.5 1 0 0 1 1 1 1 Variant UBP zinc finger UBA PF00627.31 KFM23505.1 - 6.8e-14 51.4 0.3 3.3e-08 33.3 0.0 2.5 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.6 KFM23505.1 - 1.5e-13 51.1 0.0 1.1e-09 38.4 0.0 2.5 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KFM23505.1 - 1.4e-08 34.9 0.0 1e-07 32.2 0.0 2.1 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein RuvA_C PF07499.13 KFM23505.1 - 0.0017 18.7 0.3 0.026 15.0 0.2 2.7 2 0 0 2 2 2 1 RuvA, C-terminal domain NAD_binding_2 PF03446.15 KFM23506.1 - 5.2e-37 127.4 0.5 3.9e-35 121.3 0.5 2.3 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KFM23506.1 - 1.8e-35 121.8 0.5 3.5e-35 120.9 0.5 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KFM23506.1 - 2.2e-08 34.6 0.0 5.5e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KFM23506.1 - 6.4e-05 22.9 0.1 0.00016 21.7 0.1 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KFM23506.1 - 0.00029 20.2 0.0 0.0005 19.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 KFM23506.1 - 0.00036 20.2 0.1 0.00036 20.2 0.1 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 KFM23506.1 - 0.0041 17.4 0.0 0.0075 16.5 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Shikimate_DH PF01488.20 KFM23506.1 - 0.006 16.7 0.0 0.0098 16.0 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 KFM23506.1 - 0.0067 15.9 0.1 0.013 15.0 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase UDPG_MGDP_dh_N PF03721.14 KFM23506.1 - 0.033 13.8 0.0 0.065 12.8 0.0 1.5 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 KFM23506.1 - 0.092 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Methyltransf_23 PF13489.6 KFM23507.1 - 5.1e-08 32.9 0.0 6.3e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KFM23507.1 - 1e-07 31.9 0.0 0.011 15.5 0.0 2.1 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_12 PF08242.12 KFM23507.1 - 7.6e-05 23.4 0.0 0.00018 22.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM23507.1 - 0.0043 16.9 0.0 2.8 7.7 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KFM23507.1 - 0.0064 17.1 0.0 0.16 12.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM23507.1 - 0.0079 16.9 0.0 0.064 14.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Rad9 PF04139.13 KFM23508.1 - 6.5e-46 156.8 0.0 7.8e-46 156.6 0.0 1.1 1 0 0 1 1 1 1 Rad9 AAA PF00004.29 KFM23509.1 - 2.4e-91 303.0 0.0 3.3e-46 157.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFM23509.1 - 3e-25 87.7 3.5 6.2e-12 45.1 0.2 2.9 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 KFM23509.1 - 5.1e-14 52.3 0.0 6.8e-08 32.4 0.0 3.0 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KFM23509.1 - 2.1e-13 51.0 3.5 5.9e-05 23.5 0.4 4.8 2 2 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 KFM23509.1 - 1.5e-11 44.5 0.1 0.0012 18.9 0.0 4.5 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KFM23509.1 - 2.6e-11 43.9 0.0 0.00011 22.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 KFM23509.1 - 8e-10 38.4 0.2 7.3e-06 25.4 0.0 2.4 2 1 0 2 2 2 2 TIP49 P-loop domain AAA_33 PF13671.6 KFM23509.1 - 1.4e-09 38.3 0.0 0.00017 21.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KFM23509.1 - 2.3e-09 37.6 0.5 0.082 13.2 0.1 4.4 2 2 1 3 3 3 2 AAA domain AAA_28 PF13521.6 KFM23509.1 - 6.2e-07 29.8 0.1 0.0013 19.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KFM23509.1 - 9.9e-07 29.4 0.0 0.03 14.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KFM23509.1 - 1.3e-06 28.8 0.0 0.046 14.1 0.0 2.6 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.17 KFM23509.1 - 2.5e-06 27.3 0.0 0.031 14.0 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein NACHT PF05729.12 KFM23509.1 - 5.6e-06 26.4 0.0 0.038 13.9 0.0 4.1 5 0 0 5 5 4 1 NACHT domain Mg_chelatase PF01078.21 KFM23509.1 - 7e-06 25.6 2.1 0.069 12.5 0.2 3.2 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KFM23509.1 - 1.1e-05 25.4 0.0 0.2 11.7 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 KFM23509.1 - 1.3e-05 25.1 0.0 0.038 13.9 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KFM23509.1 - 1.7e-05 24.9 0.0 0.11 12.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 KFM23509.1 - 2.1e-05 25.0 0.2 0.44 11.1 0.0 3.3 3 1 0 3 3 3 2 ABC transporter AAA_25 PF13481.6 KFM23509.1 - 2.1e-05 24.2 7.6 0.23 11.0 0.4 4.4 2 2 1 4 4 4 2 AAA domain Rad17 PF03215.15 KFM23509.1 - 4e-05 23.6 0.0 0.24 11.3 0.0 2.2 2 0 0 2 2 2 2 Rad17 P-loop domain Zeta_toxin PF06414.12 KFM23509.1 - 4.2e-05 22.9 0.2 0.11 11.8 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin Sigma54_activat PF00158.26 KFM23509.1 - 4.6e-05 23.2 0.1 0.82 9.4 0.0 3.5 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_7 PF12775.7 KFM23509.1 - 5.1e-05 22.9 0.0 0.26 10.8 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region ATPase PF06745.13 KFM23509.1 - 5.3e-05 22.7 0.0 0.11 11.8 0.0 3.1 3 0 0 3 3 3 1 KaiC ATPase_2 PF01637.18 KFM23509.1 - 7e-05 22.8 0.0 0.091 12.7 0.0 2.4 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea AAA_17 PF13207.6 KFM23509.1 - 0.00014 22.3 0.0 0.38 11.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.6 KFM23509.1 - 0.00027 21.1 0.0 1.1 9.3 0.0 2.8 2 0 0 2 2 2 2 Sigma-54 interaction domain NB-ARC PF00931.22 KFM23509.1 - 0.00042 19.6 0.0 0.14 11.3 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain AAA_24 PF13479.6 KFM23509.1 - 0.00051 19.8 0.0 0.41 10.3 0.1 2.3 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KFM23509.1 - 0.0008 19.2 0.0 0.13 12.0 0.0 2.2 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Parvo_NS1 PF01057.17 KFM23509.1 - 0.0012 18.0 0.1 0.21 10.6 0.0 2.1 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 SKI PF01202.22 KFM23509.1 - 0.0014 18.8 0.0 3.3 7.8 0.0 3.4 4 0 0 4 4 3 1 Shikimate kinase AAA_11 PF13086.6 KFM23509.1 - 0.0016 18.3 0.0 1.2 8.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain Cytidylate_kin2 PF13189.6 KFM23509.1 - 0.0032 17.6 0.0 0.12 12.5 0.0 2.2 2 0 0 2 2 2 1 Cytidylate kinase-like family PhoH PF02562.16 KFM23509.1 - 0.0077 15.7 1.2 2.4 7.6 0.6 2.3 2 0 0 2 2 2 1 PhoH-like protein DUF815 PF05673.13 KFM23509.1 - 0.012 14.8 0.0 2.9 7.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_30 PF13604.6 KFM23509.1 - 0.016 14.9 0.2 5.4 6.7 0.1 2.6 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 KFM23509.1 - 0.021 14.2 0.0 18 4.7 0.0 3.4 2 1 1 3 3 3 0 Bacterial TniB protein CPT PF07931.12 KFM23509.1 - 0.022 14.6 0.0 0.21 11.4 0.0 2.2 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_19 PF13245.6 KFM23509.1 - 0.047 14.0 3.3 5.6 7.3 0.2 2.8 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KFM23509.1 - 0.049 13.5 0.0 4.1 7.3 0.0 2.6 2 0 0 2 2 2 0 NTPase DUF2075 PF09848.9 KFM23509.1 - 0.053 12.7 0.1 3.1 6.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.6 KFM23509.1 - 0.084 13.4 0.0 2.4 8.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KFM23509.1 - 0.085 12.6 0.0 6 6.7 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Bac_DnaA PF00308.18 KFM23509.1 - 0.17 11.7 0.0 7.2 6.4 0.0 2.5 2 1 0 2 2 2 0 Bacterial dnaA protein IPT PF01745.16 KFM23509.1 - 0.19 11.1 0.3 6.6 6.0 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase YidD PF01809.18 KFM23510.1 - 1.2e-25 89.1 0.2 1.4e-25 89.0 0.2 1.0 1 0 0 1 1 1 1 Putative membrane protein insertion efficiency factor DUF3134 PF11332.8 KFM23511.1 - 0.00074 19.8 0.4 0.0016 18.7 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3134) DUF2839 PF10999.8 KFM23512.1 - 1.4e-05 25.4 3.5 1.6e-05 25.2 3.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2839) Cupin_8 PF13621.6 KFM23513.1 - 2.3e-06 27.5 0.1 2.3e-06 27.5 0.1 1.1 1 0 0 1 1 1 1 Cupin-like domain NmrA PF05368.13 KFM23514.1 - 3.6e-10 39.8 0.0 5.4e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFM23514.1 - 1.7e-06 28.0 0.0 2.9e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding PRKCSH PF07915.13 KFM23515.1 - 1e-10 42.5 3.5 1.7e-10 41.8 3.5 1.4 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 KFM23515.1 - 7.1e-07 29.0 2.3 1.1e-06 28.5 2.3 1.3 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein Ribosomal_L1 PF00687.21 KFM23516.1 - 7.2e-38 130.4 1.9 7.9e-32 110.7 0.7 2.1 1 1 1 2 2 2 2 Ribosomal protein L1p/L10e family WD40 PF00400.32 KFM23517.1 - 6.5e-20 71.1 8.5 1.2e-05 26.0 0.1 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM23517.1 - 1.1e-05 25.6 0.1 0.22 11.9 0.1 4.1 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFM23517.1 - 0.0029 16.3 1.2 0.0089 14.7 0.1 2.1 1 1 0 2 2 2 1 Nucleoporin Nup120/160 Pribosyltran PF00156.27 KFM23518.1 - 2.3e-21 76.0 0.1 2.9e-21 75.6 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KFM23518.1 - 0.0069 15.9 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyl_synth PF14572.6 KFM23518.1 - 0.083 12.9 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain Ntox8 PF15545.6 KFM23519.1 - 0.16 12.1 0.0 0.61 10.2 0.0 1.7 1 1 1 2 2 2 0 Bacterial toxin 8 CRT-like PF08627.10 KFM23523.1 - 4e-11 42.4 11.2 0.00084 18.4 0.4 3.0 1 1 2 3 3 3 3 CRT-like, chloroquine-resistance transporter-like Mg-por_mtran_C PF07109.11 KFM23524.1 - 2.4e-34 117.6 0.6 3.8e-34 116.9 0.0 1.6 2 0 0 2 2 2 1 Magnesium-protoporphyrin IX methyltransferase C-terminus Methyltransf_25 PF13649.6 KFM23524.1 - 2.5e-12 47.4 0.0 5.9e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM23524.1 - 1.1e-09 39.0 0.0 5.5e-09 36.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM23524.1 - 1.7e-08 34.5 0.0 2.1e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFM23524.1 - 1.7e-07 31.8 0.0 4.4e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM23524.1 - 5.5e-07 29.5 0.0 1.1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 KFM23524.1 - 1.5e-05 24.6 0.4 0.0077 15.7 0.3 2.2 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain Ubie_methyltran PF01209.18 KFM23524.1 - 3.5e-05 23.3 0.0 6.3e-05 22.4 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 KFM23524.1 - 0.00033 20.7 0.0 0.00049 20.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFM23524.1 - 0.00088 18.9 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KFM23524.1 - 0.00092 18.7 0.0 0.00092 18.7 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 KFM23524.1 - 0.0053 16.7 0.0 0.012 15.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 KFM23524.1 - 0.03 13.6 0.0 0.064 12.5 0.0 1.5 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 KFM23524.1 - 0.1 12.3 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase PCMT PF01135.19 KFM23524.1 - 0.16 11.7 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Na_H_Exchanger PF00999.21 KFM23525.1 - 2.6e-53 181.2 34.8 3e-53 181.0 34.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF2062 PF09835.9 KFM23525.1 - 0.17 11.8 16.6 0.16 11.8 2.4 3.4 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2062) PALP PF00291.25 KFM23526.1 - 7.4e-70 235.7 0.5 8.3e-70 235.5 0.5 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme MnmE_helical PF12631.7 KFM23527.1 - 1.5e-45 155.9 0.0 1.7e-45 155.7 0.0 1.0 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 KFM23527.1 - 3.2e-25 88.7 0.0 1e-24 87.1 0.0 1.8 2 0 0 2 2 2 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 KFM23527.1 - 1.2e-19 70.4 0.0 1.9e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFM23527.1 - 7.1e-11 41.9 0.0 1.1e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KFM23527.1 - 4.6e-07 30.0 0.0 1.4e-06 28.5 0.0 1.7 1 1 1 2 2 2 1 Dynamin family ABC_tran PF00005.27 KFM23527.1 - 0.0035 17.8 0.0 0.0072 16.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_28 PF13521.6 KFM23527.1 - 0.0055 17.0 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KFM23527.1 - 0.026 14.4 0.0 0.12 12.2 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase TAXi_N PF14543.6 KFM23528.1 - 7.4e-38 130.6 4.5 1e-37 130.1 4.5 1.2 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp PF00026.23 KFM23528.1 - 7e-17 61.8 0.1 5.4e-11 42.5 0.0 2.7 2 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.6 KFM23528.1 - 7e-06 25.9 0.1 2.5e-05 24.1 0.0 1.8 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal Arm PF00514.23 KFM23529.1 - 0.00068 19.6 2.9 0.62 10.2 0.1 3.9 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Ribonuc_red_lgC PF02867.15 KFM23530.1 - 3.7e-183 609.8 0.0 4.5e-183 609.5 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KFM23530.1 - 4.7e-23 81.0 0.0 1.5e-22 79.4 0.0 1.9 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 KFM23530.1 - 2.8e-16 59.9 0.0 1.2e-15 57.8 0.0 2.2 2 1 0 2 2 2 1 ATP cone domain ALMT PF11744.8 KFM23531.1 - 6.7e-09 35.1 3.0 1.2e-08 34.3 3.0 1.2 1 0 0 1 1 1 1 Aluminium activated malate transporter FUSC_2 PF13515.6 KFM23531.1 - 1.5e-05 25.1 6.0 1.5e-05 25.1 6.0 1.6 2 0 0 2 2 2 1 Fusaric acid resistance protein-like Glyco_tranf_2_4 PF13704.6 KFM23531.1 - 0.049 14.2 0.1 0.11 13.0 0.1 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 Peptidase_M48 PF01435.18 KFM23532.1 - 1.1e-15 57.9 2.8 9.4e-11 41.8 0.4 2.7 2 1 1 3 3 3 2 Peptidase family M48 SprT-like PF10263.9 KFM23532.1 - 0.19 11.6 1.4 0.35 10.7 1.4 1.5 1 1 0 1 1 1 0 SprT-like family DUF2268 PF10026.9 KFM23532.1 - 0.22 11.0 0.0 0.32 10.6 0.0 1.2 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) TetR_C_11 PF16859.5 KFM23532.1 - 1.6 9.0 5.6 9.8 6.5 0.7 2.8 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain DnaJ_C PF01556.18 KFM23533.1 - 1.4e-36 125.8 0.0 2e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KFM23533.1 - 9.8e-25 86.5 0.5 1.8e-24 85.6 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KFM23533.1 - 2.9e-10 40.3 19.5 6e-10 39.3 19.5 1.6 1 0 0 1 1 1 1 DnaJ central domain DUF3739 PF12545.8 KFM23533.1 - 0.038 14.5 0.3 0.71 10.4 0.1 2.7 2 0 0 2 2 2 0 Filamentous haemagglutinin family outer membrane protein zinc-ribbons_6 PF07191.12 KFM23533.1 - 0.081 12.9 6.5 0.16 12.0 6.5 1.5 1 0 0 1 1 1 0 zinc-ribbons Ribosomal_S7 PF00177.21 KFM23534.1 - 6.2e-39 133.0 1.5 8.1e-39 132.6 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Peptidase_C47 PF05543.13 KFM23534.1 - 0.043 13.4 0.0 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 Staphopain peptidase C47 Rsm1 PF08600.10 KFM23534.1 - 0.078 13.1 0.0 0.21 11.8 0.0 1.8 1 1 0 1 1 1 0 Rsm1-like Biotin_lipoyl PF00364.22 KFM23535.1 - 3.5e-16 58.8 0.3 6.2e-16 58.0 0.3 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KFM23535.1 - 0.00062 19.6 1.4 0.056 13.3 0.1 2.2 1 1 1 2 2 2 2 Biotin-lipoyl like GCV_H PF01597.19 KFM23535.1 - 0.00078 19.3 0.1 0.0011 18.8 0.1 1.2 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 KFM23535.1 - 0.012 15.5 0.1 0.025 14.5 0.1 1.5 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain HlyD_3 PF13437.6 KFM23535.1 - 0.02 15.6 0.3 0.059 14.1 0.2 1.7 1 1 1 2 2 2 0 HlyD family secretion protein PYNP_C PF07831.13 KFM23535.1 - 0.12 12.0 0.1 0.23 11.1 0.0 1.5 1 1 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain AAA_6 PF12774.7 KFM23536.1 - 1.1e-141 471.5 0.0 2.9e-140 466.9 0.0 2.9 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region MT PF12777.7 KFM23536.1 - 2.7e-89 299.6 6.2 5.6e-89 298.5 6.2 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.7 KFM23536.1 - 3.5e-75 251.9 0.0 2.7e-73 245.8 0.0 2.5 2 0 0 2 2 2 1 ATP-binding dynein motor region Dynein_C PF18199.1 KFM23536.1 - 5.4e-72 242.6 0.1 1.4e-71 241.3 0.1 1.7 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain DHC_N1 PF08385.12 KFM23536.1 - 2.5e-70 237.7 0.0 5.8e-37 127.6 0.0 2.5 1 1 1 2 2 2 2 Dynein heavy chain, N-terminal region 1 AAA_8 PF12780.7 KFM23536.1 - 9.6e-62 208.6 0.0 3.6e-61 206.8 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 KFM23536.1 - 2.2e-59 200.0 0.0 1.8e-54 184.0 0.0 3.6 3 0 0 3 3 3 1 P-loop containing dynein motor region DHC_N2 PF08393.13 KFM23536.1 - 2e-36 126.0 3.6 2.4e-19 69.7 0.2 3.8 1 1 2 3 3 3 3 Dynein heavy chain, N-terminal region 2 AAA_5 PF07728.14 KFM23536.1 - 3.1e-18 66.1 0.0 4.9e-09 36.3 0.0 4.0 3 1 0 3 3 3 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 KFM23536.1 - 1.6e-12 47.6 0.4 4.6e-12 46.1 0.4 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KFM23536.1 - 5.3e-11 42.6 0.0 2.7e-08 33.9 0.0 3.3 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 KFM23536.1 - 6.5e-09 35.8 0.0 2.1e-07 30.9 0.0 2.5 1 1 1 2 2 2 1 Dynein heavy chain AAA lid domain AAA PF00004.29 KFM23536.1 - 1.3e-07 32.1 0.0 0.14 12.5 0.0 4.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFM23536.1 - 4.4e-07 30.4 14.7 0.00094 19.6 0.0 6.2 6 0 0 6 6 4 2 AAA ATPase domain AAA_lid_1 PF17857.1 KFM23536.1 - 1e-06 28.9 0.0 2.9e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KFM23536.1 - 1.2e-06 28.8 0.3 1.4 9.2 0.0 4.7 4 0 0 4 4 3 2 AAA domain AAA_18 PF13238.6 KFM23536.1 - 4.7e-06 27.2 0.0 0.31 11.6 0.0 4.2 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 KFM23536.1 - 7.7e-05 23.0 0.1 1.6 9.1 0.0 3.7 3 0 0 3 3 3 1 RNA helicase ABC_tran PF00005.27 KFM23536.1 - 0.0001 22.8 0.2 0.52 10.8 0.0 3.6 4 0 0 4 4 2 1 ABC transporter AAA_30 PF13604.6 KFM23536.1 - 0.00013 21.7 8.4 0.048 13.4 0.1 4.4 4 0 0 4 4 4 1 AAA domain Mg_chelatase PF01078.21 KFM23536.1 - 0.0015 17.9 0.2 0.36 10.2 0.0 2.9 3 0 0 3 3 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KFM23536.1 - 0.0036 17.5 0.1 12 6.1 0.0 4.0 3 0 0 3 3 3 0 AAA domain TsaE PF02367.17 KFM23536.1 - 0.0056 16.7 0.4 16 5.5 0.0 3.6 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 KFM23536.1 - 0.0068 15.6 0.1 0.59 9.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Cytidylate_kin PF02224.18 KFM23536.1 - 0.01 15.6 0.4 6.3 6.5 0.0 3.5 3 0 0 3 3 3 0 Cytidylate kinase Sigma54_activ_2 PF14532.6 KFM23536.1 - 0.011 15.8 0.1 11 6.1 0.0 3.1 3 0 0 3 3 2 0 Sigma-54 interaction domain Sigma54_activat PF00158.26 KFM23536.1 - 0.021 14.5 0.0 8.6 6.0 0.0 2.7 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 KFM23536.1 - 0.021 14.4 0.0 0.021 14.4 0.0 3.5 4 0 0 4 4 4 0 AAA domain Rad17 PF03215.15 KFM23536.1 - 0.035 14.0 0.0 43 3.9 0.0 3.5 3 0 0 3 3 3 0 Rad17 P-loop domain Zeta_toxin PF06414.12 KFM23536.1 - 0.054 12.8 0.6 5.2 6.3 0.1 3.1 3 0 0 3 3 3 0 Zeta toxin CENP-K PF11802.8 KFM23536.1 - 0.083 12.5 4.7 0.11 12.1 2.3 2.5 2 0 0 2 2 2 0 Centromere-associated protein K AAA_19 PF13245.6 KFM23536.1 - 0.79 10.1 9.6 24 5.2 0.0 5.2 5 0 0 5 5 5 0 AAA domain DUF1664 PF07889.12 KFM23536.1 - 0.97 9.5 12.9 4 7.5 1.5 5.4 6 0 0 6 6 4 0 Protein of unknown function (DUF1664) AAA_28 PF13521.6 KFM23536.1 - 1.7 8.8 5.4 22 5.2 0.1 4.2 4 0 0 4 4 3 0 AAA domain NACHT PF05729.12 KFM23536.1 - 5.1 7.0 8.8 6.6 6.6 0.1 4.2 5 0 0 5 5 3 0 NACHT domain COG5 PF10392.9 KFM23536.1 - 5.9 7.1 6.9 22 5.2 0.6 3.8 3 0 0 3 3 3 0 Golgi transport complex subunit 5 DUF737 PF05300.11 KFM23536.1 - 5.9 7.2 9.2 1.6 9.1 4.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF737) ribosomal_L24 PF17136.4 KFM23537.1 - 6e-21 74.6 2.9 6e-21 74.6 2.9 1.8 2 0 0 2 2 2 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 KFM23537.1 - 9.4e-06 25.4 7.5 2.7e-05 23.9 7.5 1.8 1 0 0 1 1 1 1 KOW motif Citrate_synt PF00285.21 KFM23540.1 - 4.9e-106 354.8 0.0 6e-106 354.5 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Proteasome PF00227.26 KFM23542.1 - 4.1e-33 114.5 0.3 3.3e-31 108.2 0.0 2.1 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 KFM23542.1 - 1.4e-14 53.4 0.1 2.3e-14 52.7 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SAC3_GANP PF03399.16 KFM23543.1 - 4.5e-59 200.2 2.2 9.5e-30 104.0 0.0 2.5 1 1 1 2 2 2 2 SAC3/GANP family MFS_1 PF07690.16 KFM23544.1 - 7.1e-29 100.8 37.1 1.3e-25 90.1 35.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily AsmA_2 PF13502.6 KFM23544.1 - 0.068 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 AsmA-like C-terminal region ANAPC4_WD40 PF12894.7 KFM23545.1 - 2.3e-12 47.0 0.0 0.047 14.0 0.0 4.3 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFM23545.1 - 9.8e-06 26.2 1.0 0.11 13.4 0.4 4.1 3 1 0 3 3 3 2 WD domain, G-beta repeat eIF2A PF08662.11 KFM23545.1 - 0.00015 21.7 0.0 0.017 15.0 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A PspC PF04024.12 KFM23545.1 - 0.038 13.8 0.1 0.21 11.4 0.0 2.0 2 0 0 2 2 2 0 PspC domain SKN1 PF03935.15 KFM23546.1 - 1.1e-93 314.3 0.3 1.7e-93 313.7 0.3 1.2 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.21 KFM23546.1 - 2.3e-10 40.2 0.6 0.00024 20.6 0.1 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 nos_propeller_2 PF18793.1 KFM23546.1 - 0.027 14.8 0.0 0.073 13.4 0.0 1.7 1 0 0 1 1 1 0 Nitrous oxide reductase propeller repeat 2 Cellsynth_D PF03500.13 KFM23546.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Cellulose synthase subunit D SKN1 PF03935.15 KFM23547.1 - 2.2e-99 333.2 5.0 3.4e-99 332.5 5.0 1.2 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.21 KFM23547.1 - 3.1e-07 30.1 0.4 0.00059 19.4 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 DUF3667 PF12412.8 KFM23547.1 - 0.14 11.6 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3667) Castor_Poll_mid PF06241.12 KFM23548.1 - 4.1e-07 29.9 0.0 2e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 Castor and Pollux, part of voltage-gated ion channel TrkA_N PF02254.18 KFM23548.1 - 0.0028 17.9 0.1 0.074 13.3 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain zf-C3HC4_3 PF13920.6 KFM23549.1 - 8.5e-07 28.7 8.1 1.2e-06 28.2 8.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM23549.1 - 8.9e-07 29.1 10.8 8.9e-07 29.1 10.8 1.4 2 0 0 2 2 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KFM23549.1 - 4.7e-05 23.3 3.9 4.7e-05 23.3 3.9 1.7 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFM23549.1 - 6.6e-05 22.7 10.7 0.00011 22.0 10.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM23549.1 - 0.00014 21.8 9.4 0.00021 21.2 9.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 KFM23549.1 - 0.00069 19.3 4.9 0.0015 18.3 4.9 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_4 PF14570.6 KFM23549.1 - 0.0007 19.3 8.0 0.0013 18.5 8.0 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 KFM23549.1 - 0.0013 18.5 11.4 0.0024 17.7 11.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KFM23549.1 - 0.0058 16.5 4.5 0.012 15.5 4.5 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 KFM23549.1 - 0.0091 15.8 8.0 0.017 14.9 8.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KFM23549.1 - 0.029 14.5 10.6 0.083 13.1 10.6 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-UDP PF14569.6 KFM23549.1 - 0.052 13.7 4.5 0.088 12.9 4.5 1.5 1 1 0 1 1 1 0 Zinc-binding RING-finger Rad50_zn_hook PF04423.14 KFM23549.1 - 0.075 12.9 0.5 0.14 12.0 0.5 1.3 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-ANAPC11 PF12861.7 KFM23549.1 - 0.25 11.4 9.6 0.97 9.5 9.6 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KFM23549.1 - 1.2 9.5 13.4 6.1 7.2 13.4 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain UBD PF16455.5 KFM23550.1 - 3.5e-21 75.4 0.0 7.1e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-binding domain Neuropep_like PF15161.6 KFM23550.1 - 0.18 11.5 0.7 45 3.8 0.2 3.0 3 0 0 3 3 3 0 Neuropeptide-like zinc_ribbon_6 PF14599.6 KFM23550.1 - 0.23 11.5 4.2 6.5 6.8 0.1 2.5 2 0 0 2 2 2 0 Zinc-ribbon RecA PF00154.21 KFM23551.1 - 5.2e-104 347.4 0.8 2.6e-103 345.1 0.8 1.9 1 1 0 1 1 1 1 recA bacterial DNA recombination protein Rad51 PF08423.11 KFM23551.1 - 1.1e-09 38.0 0.1 0.00028 20.2 0.0 2.2 1 1 1 2 2 2 2 Rad51 ATPase PF06745.13 KFM23551.1 - 6.8e-05 22.3 0.1 0.00048 19.5 0.0 2.2 1 1 0 2 2 2 1 KaiC AAA_16 PF13191.6 KFM23551.1 - 0.0018 18.7 0.1 0.0091 16.4 0.1 2.0 2 0 0 2 2 2 1 AAA ATPase domain MobB PF03205.14 KFM23551.1 - 0.0072 16.2 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.6 KFM23551.1 - 0.029 14.1 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KFM23551.1 - 0.037 13.6 1.0 0.21 11.1 0.1 2.2 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 KFM23551.1 - 0.056 14.0 0.0 0.16 12.5 0.0 1.9 2 1 0 2 2 2 0 ABC transporter CbiA PF01656.23 KFM23551.1 - 0.1 12.7 0.0 0.25 11.4 0.0 1.9 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_35 PF14516.6 KFM23551.1 - 0.24 10.2 0.0 0.38 9.5 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Yae1_N PF09811.9 KFM23552.1 - 3e-08 33.2 3.1 7.4e-08 32.0 3.1 1.7 1 0 0 1 1 1 1 Essential protein Yae1, N terminal adh_short PF00106.25 KFM23553.1 - 2.4e-43 147.9 0.5 3.5e-43 147.3 0.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM23553.1 - 4.9e-32 111.4 0.1 6.7e-32 110.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM23553.1 - 3e-12 46.8 1.0 8.3e-12 45.4 0.4 1.9 2 0 0 2 2 2 1 KR domain DUF1776 PF08643.10 KFM23553.1 - 1.7e-07 30.9 0.0 2.4e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.8 KFM23553.1 - 0.0086 15.8 0.0 0.13 12.0 0.0 2.5 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.21 KFM23553.1 - 0.038 13.4 0.1 0.072 12.5 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ribonuc_2-5A PF06479.12 KFM23556.1 - 9.4e-38 129.3 0.0 1.3e-37 128.8 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 KFM23556.1 - 5.5e-34 117.7 0.0 8.1e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM23556.1 - 5.7e-22 78.2 0.0 8.3e-22 77.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase zf-CCCH PF00642.24 KFM23556.1 - 2.7e-14 52.7 18.8 4.5e-09 36.0 5.0 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PQQ PF01011.21 KFM23556.1 - 8.4e-08 31.8 0.1 0.0008 19.2 0.0 2.8 2 0 0 2 2 2 2 PQQ enzyme repeat PQQ_2 PF13360.6 KFM23556.1 - 2.1e-07 30.8 1.2 0.0034 17.0 0.2 2.9 2 1 0 2 2 2 2 PQQ-like domain Kinase-like PF14531.6 KFM23556.1 - 2.1e-07 30.5 0.0 3e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFM23556.1 - 0.0067 15.8 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFM23556.1 - 0.007 16.3 1.0 0.03 14.2 1.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFM23556.1 - 0.0072 15.2 0.0 0.011 14.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase zf_CCCH_4 PF18345.1 KFM23556.1 - 0.0078 16.2 8.3 0.0078 16.2 8.3 2.6 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH_4 PF18044.1 KFM23556.1 - 0.015 15.1 16.8 0.37 10.6 3.8 2.4 2 0 0 2 2 2 0 CCCH-type zinc finger PQQ_3 PF13570.6 KFM23556.1 - 0.35 11.4 13.6 9.2 6.9 0.2 5.0 5 0 0 5 5 4 0 PQQ-like domain zf-CCCH_2 PF14608.6 KFM23556.1 - 3.5 8.2 18.4 3 8.5 5.8 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger DUF1180 PF06679.12 KFM23557.1 - 1.4 9.3 4.3 1.4 9.3 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) UPF0061 PF02696.14 KFM23558.1 - 1.7e-118 396.4 0.0 2e-118 396.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Stealth_CR1 PF17101.5 KFM23558.1 - 0.046 13.5 1.4 0.12 12.2 1.4 1.7 1 0 0 1 1 1 0 Stealth protein CR1, conserved region 1 VTC PF09359.10 KFM23559.1 - 9.1e-59 199.1 0.0 1.2e-58 198.7 0.0 1.2 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 KFM23559.1 - 2.6e-12 47.0 0.4 2.6e-12 47.0 0.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) MTABC_N PF16185.5 KFM23559.1 - 0.013 15.0 0.5 0.025 14.1 0.5 1.4 1 0 0 1 1 1 0 Mitochondrial ABC-transporter N-terminal five TM region PseudoU_synth_2 PF00849.22 KFM23560.1 - 2.9e-19 69.7 0.0 1.8e-10 41.1 0.0 2.5 2 1 0 2 2 2 2 RNA pseudouridylate synthase Aminotran_4 PF01063.19 KFM23561.1 - 1.7e-09 37.9 0.0 1.6e-08 34.7 0.0 2.0 1 1 1 2 2 2 1 Amino-transferase class IV CDP-OH_P_transf PF01066.21 KFM23562.1 - 1e-08 35.8 0.1 2.9e-08 34.4 0.1 1.8 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Pkinase PF00069.25 KFM23563.1 - 4.9e-63 213.0 0.0 6.4e-63 212.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM23563.1 - 1.6e-26 93.2 0.0 2.3e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFM23563.1 - 0.0036 17.3 0.0 0.22 11.4 0.1 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family CCCAP PF15964.5 KFM23563.1 - 0.035 12.4 0.3 0.045 12.1 0.3 1.1 1 0 0 1 1 1 0 Centrosomal colon cancer autoantigen protein family Haspin_kinase PF12330.8 KFM23563.1 - 0.04 12.9 0.0 0.073 12.0 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DUF4247 PF14042.6 KFM23563.1 - 0.07 13.8 0.0 6.7 7.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4247) ING PF12998.7 KFM23563.1 - 0.12 13.0 1.3 0.27 11.8 1.3 1.6 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding RNase_P_Rpp14 PF01900.19 KFM23565.1 - 2.9e-23 82.1 0.0 3.3e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family SAS-6_N PF16531.5 KFM23566.1 - 2.3e-13 50.5 0.0 5.3e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal RRM_1 PF00076.22 KFM23566.1 - 0.00015 21.5 0.0 0.051 13.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cep57_CLD_2 PF14197.6 KFM23566.1 - 0.014 15.4 8.0 0.014 15.4 8.0 2.3 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 RAM PF15320.6 KFM23566.1 - 0.16 12.6 6.3 0.4 11.3 6.3 1.6 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein bZIP_1 PF00170.21 KFM23567.1 - 4.9e-11 42.6 8.6 9.8e-11 41.6 8.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFM23567.1 - 3.4e-09 36.6 8.3 7.6e-09 35.5 8.3 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFM23567.1 - 0.018 15.5 8.3 0.034 14.7 8.3 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor WD40 PF00400.32 KFM23568.1 - 1.5e-17 63.6 12.2 1e-06 29.4 0.0 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM23568.1 - 7.7e-06 26.1 0.0 1.1 9.6 0.0 4.4 2 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Cyt-b5 PF00173.28 KFM23569.1 - 6.2e-17 61.5 0.1 1.2e-16 60.6 0.1 1.5 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CobN-Mg_chel PF02514.16 KFM23570.1 - 0 1096.9 0.0 0 1096.7 0.0 1.0 1 0 0 1 1 1 1 CobN/Magnesium Chelatase DUF3479 PF11965.8 KFM23570.1 - 1.4e-47 161.8 0.3 2.9e-47 160.8 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3479) Glyco_hydro_14 PF01373.17 KFM23571.1 - 5e-86 289.2 0.0 3.2e-70 237.1 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 14 Rav1p_C PF12234.8 KFM23571.1 - 7.9e-38 130.3 0.0 9.4e-37 126.7 0.0 1.9 2 0 0 2 2 2 1 RAVE protein 1 C terminal SAVED PF18145.1 KFM23571.1 - 0.013 15.3 0.1 0.024 14.4 0.1 1.3 1 0 0 1 1 1 0 SMODS-associated and fused to various effectors sensor domain WD40 PF00400.32 KFM23571.1 - 0.17 12.8 4.3 60 4.7 0.0 5.5 5 0 0 5 5 5 0 WD domain, G-beta repeat RNase_PH PF01138.21 KFM23573.1 - 9.4e-35 120.0 0.1 1.3e-34 119.5 0.1 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KFM23573.1 - 1.5e-05 24.9 0.0 3.4e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Cyt-b5 PF00173.28 KFM23574.1 - 5.4e-19 68.1 0.0 5.5e-09 36.0 0.0 2.3 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Myb_DNA-binding PF00249.31 KFM23574.1 - 0.089 13.0 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Myb-like DNA-binding domain VRR_NUC PF08774.11 KFM23574.1 - 0.14 12.2 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 VRR-NUC domain PPDK_N PF01326.19 KFM23575.1 - 1.4e-24 87.0 0.0 2.5e-23 82.9 0.0 2.4 2 1 0 2 2 2 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain FAD_binding_3 PF01494.19 KFM23576.1 - 4.6e-17 62.3 5.6 9.2e-12 44.9 0.6 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KFM23576.1 - 2.4e-09 37.2 1.2 2.4e-09 37.2 1.2 1.8 1 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KFM23576.1 - 1.7e-07 30.6 0.4 2.9e-07 29.9 0.4 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KFM23576.1 - 7.9e-06 25.3 1.1 1.2e-05 24.7 1.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFM23576.1 - 8e-05 22.0 1.0 0.00012 21.4 1.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFM23576.1 - 0.00019 21.6 0.5 0.00019 21.6 0.5 3.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KFM23576.1 - 0.0002 20.6 1.1 0.00047 19.4 1.1 1.6 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KFM23576.1 - 0.0012 18.1 0.7 0.0019 17.4 0.7 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 KFM23576.1 - 0.0018 17.1 0.5 0.0018 17.1 0.5 1.4 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.24 KFM23576.1 - 0.0026 17.1 0.3 0.9 8.7 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Thi4 PF01946.17 KFM23576.1 - 0.011 15.0 0.3 0.02 14.1 0.3 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 KFM23576.1 - 0.062 13.9 1.0 0.062 13.9 1.0 2.5 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KFM23576.1 - 0.12 12.3 0.1 0.19 11.6 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KFM23576.1 - 0.17 11.4 1.0 1.7 8.2 0.6 2.1 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF4213 PF13938.6 KFM23576.1 - 0.76 10.0 4.1 1 9.6 0.2 2.9 3 0 0 3 3 3 0 Putative heavy-metal chelation Ribosomal_S26e PF01283.19 KFM23578.1 - 9.1e-49 164.4 5.7 1.1e-48 164.1 5.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Lipase_3 PF01764.25 KFM23579.1 - 1.1e-14 54.5 0.0 1e-05 25.5 0.0 2.9 2 1 0 2 2 2 2 Lipase (class 3) TAP_C PF03943.13 KFM23580.1 - 0.071 12.8 0.1 0.17 11.5 0.1 1.6 1 0 0 1 1 1 0 TAP C-terminal domain AP3D1 PF06375.11 KFM23580.1 - 1.4 9.1 18.2 0.41 10.9 9.2 2.4 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 RNA_pol_Rpc4 PF05132.14 KFM23580.1 - 5.9 7.3 11.4 0.89 10.0 2.8 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 NDUF_C2 PF06374.11 KFM23582.1 - 0.0033 17.5 0.0 0.0038 17.4 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) Pkinase PF00069.25 KFM23583.1 - 0.0051 16.2 0.0 0.007 15.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 KFM23584.1 - 2.4e-43 148.4 0.0 2.6e-43 148.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM23584.1 - 2.3e-20 73.0 0.0 2.8e-20 72.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM23584.1 - 0.015 14.6 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 KFM23584.1 - 0.034 13.5 0.0 0.046 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFM23584.1 - 0.077 12.9 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFM23584.1 - 0.17 10.8 0.0 0.24 10.3 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain RPN6_N PF18055.1 KFM23585.1 - 2.2e-29 102.2 1.3 5e-29 101.0 0.0 2.2 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 KFM23585.1 - 4.4e-18 65.7 0.0 1.1e-17 64.4 0.0 1.7 1 0 0 1 1 1 1 PCI domain TPR_12 PF13424.6 KFM23585.1 - 2.6e-05 24.4 7.5 0.0062 16.8 2.2 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KFM23585.1 - 0.00079 18.9 4.7 0.0044 16.4 2.3 2.4 2 0 0 2 2 2 1 MalT-like TPR region TPR_21 PF09976.9 KFM23585.1 - 0.12 12.1 5.2 0.28 10.9 0.3 3.3 3 1 0 4 4 4 0 Tetratricopeptide repeat-like domain TPR_19 PF14559.6 KFM23585.1 - 0.37 11.3 8.2 9.3 6.8 1.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFM23585.1 - 3.2 8.5 9.7 0.51 11.0 1.2 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat 4HBT PF03061.22 KFM23586.1 - 7.1e-05 23.1 0.1 0.0022 18.3 0.1 2.1 2 0 0 2 2 2 2 Thioesterase superfamily tRNA_Me_trans PF03054.16 KFM23587.1 - 8.7e-110 366.8 0.0 9.9e-110 366.7 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.17 KFM23587.1 - 8.9e-05 21.7 0.0 0.34 10.0 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Asn_synthase PF00733.21 KFM23587.1 - 0.00011 22.0 0.0 0.00021 21.1 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.13 KFM23587.1 - 0.00054 19.5 0.0 0.016 14.7 0.0 2.1 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC ThiI PF02568.14 KFM23587.1 - 0.0036 16.9 0.0 0.006 16.2 0.0 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) UPF0016 PF01169.19 KFM23588.1 - 3e-35 120.4 28.9 4.8e-19 68.5 7.7 2.7 3 0 0 3 3 3 2 Uncharacterized protein family UPF0016 DUF4064 PF13273.6 KFM23588.1 - 0.077 13.3 9.1 0.28 11.5 1.2 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) DUF5570 PF17731.1 KFM23588.1 - 0.95 9.6 3.8 2.7 8.1 0.8 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5570) Glyco_transf_29 PF00777.18 KFM23589.1 - 1.1e-15 57.8 0.0 5.6e-13 48.9 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase family 29 (sialyltransferase) EGF_2 PF07974.13 KFM23589.1 - 1.3 9.5 6.1 3 8.3 6.1 1.6 1 0 0 1 1 1 0 EGF-like domain Met_gamma_lyase PF06838.11 KFM23590.1 - 3.7e-137 457.1 0.0 5.4e-137 456.6 0.0 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase Mito_carr PF00153.27 KFM23590.1 - 6e-62 205.6 0.2 9.3e-21 73.6 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Cys_Met_Meta_PP PF01053.20 KFM23590.1 - 1.8e-05 23.5 0.0 7.1e-05 21.5 0.0 1.8 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme PDZ_6 PF17820.1 KFM23590.1 - 0.015 15.1 0.1 0.3 11.0 0.0 2.6 2 0 0 2 2 2 0 PDZ domain ALAD PF00490.21 KFM23590.1 - 0.16 11.1 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Delta-aminolevulinic acid dehydratase Glyco_transf_5 PF08323.11 KFM23591.1 - 7e-51 173.3 0.0 2.5e-50 171.5 0.0 1.8 2 0 0 2 2 2 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KFM23591.1 - 4.7e-12 45.8 0.0 1.3e-11 44.3 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KFM23591.1 - 5e-12 46.5 2.8 1.7e-11 44.8 2.8 1.9 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 KFM23591.1 - 9.3e-09 35.5 1.3 1.3e-07 31.8 1.3 2.4 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KFM23591.1 - 2.8e-08 34.3 0.1 6e-08 33.2 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Acyltransferase PF01553.21 KFM23592.1 - 5.5e-28 97.3 0.0 7.5e-28 96.8 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransferase PF01553.21 KFM23593.1 - 8.7e-29 99.9 0.0 1.1e-28 99.5 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Mito_carr PF00153.27 KFM23594.1 - 6.6e-50 167.0 1.4 1.6e-16 60.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein NUDIX PF00293.28 KFM23595.1 - 0.002 18.2 0.0 0.003 17.6 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DPBB_1 PF03330.18 KFM23596.1 - 4.7e-14 52.4 0.0 1.2e-13 51.1 0.0 1.7 1 0 0 1 1 1 1 Lytic transglycolase Pollen_allerg_1 PF01357.21 KFM23596.1 - 1e-12 47.9 0.9 1e-12 47.9 0.9 2.3 2 0 0 2 2 2 1 Pollen allergen IU_nuc_hydro PF01156.19 KFM23597.1 - 3.8e-84 282.8 0.8 4.6e-84 282.6 0.8 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DSPc PF00782.20 KFM23598.1 - 2.3e-13 50.1 0.0 3.9e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Chon_Sulph_att PF06566.11 KFM23598.1 - 0.043 13.7 1.5 0.058 13.3 1.5 1.3 1 0 0 1 1 1 0 Chondroitin sulphate attachment domain DUF2934 PF11154.8 KFM23598.1 - 0.12 12.1 0.4 0.12 12.1 0.4 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2934) DUF1336 PF07059.12 KFM23600.1 - 6.3e-58 196.5 0.0 8.8e-58 196.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) START PF01852.19 KFM23600.1 - 8.7e-13 48.2 0.1 1.6e-12 47.3 0.1 1.3 1 0 0 1 1 1 1 START domain PH PF00169.29 KFM23600.1 - 0.099 13.2 0.0 0.27 11.7 0.0 1.8 1 1 0 1 1 1 0 PH domain Glycos_transf_4 PF00953.21 KFM23601.1 - 5.2e-34 117.5 10.3 1.1e-32 113.2 9.6 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 4 DUF2157 PF09925.9 KFM23601.1 - 0.79 9.5 0.0 0.79 9.5 0.0 3.2 3 1 1 4 4 4 0 Predicted membrane protein (DUF2157) RNA_pol_A_bac PF01000.26 KFM23602.1 - 4.1e-22 78.7 0.0 7.5e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KFM23602.1 - 1.2e-21 75.9 0.0 1.9e-21 75.2 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain CytochromB561_N PF09786.9 KFM23603.1 - 2.3e-36 126.0 0.0 2.9e-36 125.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome B561, N terminal PAF-AH_p_II PF03403.13 KFM23604.1 - 2e-46 158.3 0.0 7.3e-46 156.4 0.0 1.7 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KFM23604.1 - 7.5e-08 31.6 0.0 2.2e-07 30.1 0.0 1.7 1 1 0 1 1 1 1 Chlorophyllase enzyme DLH PF01738.18 KFM23604.1 - 7.5e-06 25.7 0.3 3.4e-05 23.5 0.3 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KFM23604.1 - 0.0001 21.6 0.2 0.3 10.3 0.1 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KFM23604.1 - 0.00033 20.2 0.2 0.00074 19.1 0.1 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Chlorophyllase PF07224.11 KFM23604.1 - 0.021 13.9 0.1 4.2 6.3 0.0 2.1 2 0 0 2 2 2 0 Chlorophyllase Abhydrolase_6 PF12697.7 KFM23604.1 - 0.054 14.1 17.0 0.019 15.6 13.4 2.0 1 1 1 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFM23604.1 - 0.077 12.6 0.5 0.2 11.2 0.1 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold 2Fe-2S_Ferredox PF11591.8 KFM23604.1 - 1.3 8.9 4.1 1.5 8.8 0.8 2.5 2 0 0 2 2 2 0 Ferredoxin chloroplastic transit peptide Glyco_hydro_35 PF01301.19 KFM23605.1 - 1.2e-96 324.0 0.0 9.5e-82 275.1 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 KFM23605.1 - 0.00022 20.7 0.1 0.00056 19.3 0.1 1.5 1 1 0 1 1 1 1 Beta-galactosidase TPR_12 PF13424.6 KFM23606.1 - 0.014 15.7 1.2 0.16 12.2 0.3 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFM23606.1 - 0.017 14.9 3.1 1.6 8.7 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFM23606.1 - 0.11 12.8 3.0 0.78 10.1 0.1 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFM23606.1 - 0.17 12.1 7.3 0.83 9.9 3.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat PP2C PF00481.21 KFM23607.1 - 2.7e-71 240.2 0.0 7.7e-58 196.1 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C PF00481.21 KFM23608.1 - 3e-67 227.0 0.0 4.3e-56 190.4 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 KFM23608.1 - 0.0001 22.1 0.3 0.0013 18.4 0.0 2.2 2 0 0 2 2 2 1 Protein phosphatase 2C Ham1p_like PF01725.16 KFM23609.1 - 5.7e-46 156.8 0.0 6.9e-46 156.5 0.0 1.0 1 0 0 1 1 1 1 Ham1 family DUF92 PF01940.16 KFM23610.1 - 0.00091 18.7 4.6 0.0021 17.5 4.5 1.6 1 1 0 1 1 1 1 Integral membrane protein DUF92 Aminotran_3 PF00202.21 KFM23611.1 - 7.7e-70 235.6 0.0 1e-69 235.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III NAD_binding_10 PF13460.6 KFM23611.1 - 5.1e-24 85.2 0.2 1.1e-13 51.5 0.2 2.4 2 0 0 2 2 2 2 NAD(P)H-binding NmrA PF05368.13 KFM23611.1 - 1.1e-10 41.5 0.0 1.6e-09 37.6 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.21 KFM23611.1 - 9.1e-10 38.4 0.1 1.5e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFM23611.1 - 0.00037 20.0 0.0 0.00055 19.4 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KFM23611.1 - 0.0015 17.7 0.2 0.027 13.6 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KFM23611.1 - 0.0029 16.7 0.2 0.0044 16.1 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KFM23611.1 - 0.0076 15.4 4.2 0.024 13.8 3.4 2.2 2 1 0 2 2 2 1 Male sterility protein CIA30 PF08547.12 KFM23611.1 - 0.013 15.5 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 Complex I intermediate-associated protein 30 (CIA30) adh_short PF00106.25 KFM23611.1 - 0.16 11.4 0.0 0.37 10.2 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase Phytase-like PF13449.6 KFM23612.1 - 5.8e-07 29.7 0.0 8.5e-06 25.9 0.0 2.2 1 1 2 3 3 3 1 Esterase-like activity of phytase SdiA-regulated PF06977.11 KFM23612.1 - 4.4e-06 26.1 0.0 0.012 14.8 0.0 3.6 3 1 1 4 4 4 3 SdiA-regulated THF_DHG_CYH_C PF02882.19 KFM23614.1 - 5.8e-68 227.2 0.2 8.7e-68 226.7 0.2 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KFM23614.1 - 4.4e-35 120.5 0.2 7.6e-35 119.7 0.2 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 KFM23614.1 - 0.0048 15.9 0.3 0.0073 15.3 0.3 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family PsbY PF06298.11 KFM23615.1 - 1.6e-14 53.5 3.9 1.9e-09 37.2 0.2 2.5 2 0 0 2 2 2 2 Photosystem II protein Y (PsbY) Radical_SAM_C PF16199.5 KFM23615.1 - 3.6e-10 39.7 0.0 5.9e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Radical_SAM C-terminal domain SNARE PF05739.19 KFM23617.1 - 1.2e-05 25.2 1.3 5.3e-05 23.1 1.3 2.2 1 0 0 1 1 1 1 SNARE domain Mce4_CUP1 PF11887.8 KFM23617.1 - 0.0056 16.2 1.8 0.0063 16.0 0.1 1.8 2 0 0 2 2 2 1 Cholesterol uptake porter CUP1 of Mce4, putative FliD_C PF07195.12 KFM23617.1 - 0.046 13.1 3.2 0.11 12.0 0.7 2.1 1 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus F_actin_bind PF08919.10 KFM23617.1 - 0.07 13.2 0.6 2 8.6 0.0 2.5 2 0 0 2 2 2 0 F-actin binding DAGK_prokar PF01219.19 KFM23617.1 - 0.13 12.1 0.5 0.3 11.0 0.1 1.7 2 0 0 2 2 2 0 Prokaryotic diacylglycerol kinase CHDCT2 PF08074.11 KFM23617.1 - 0.22 11.7 3.2 0.94 9.6 0.8 2.6 2 1 0 2 2 2 0 CHDCT2 (NUC038) domain Use1 PF09753.9 KFM23617.1 - 0.61 9.8 7.8 3.9 7.1 7.8 2.0 1 1 0 1 1 1 0 Membrane fusion protein Use1 UPF0242 PF06785.11 KFM23617.1 - 4.5 7.3 6.9 4.9 7.2 0.9 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus ZapB PF06005.12 KFM23617.1 - 5.5 7.5 17.6 1.7 9.1 0.6 3.2 3 1 0 3 3 3 0 Cell division protein ZapB SMBP PF16785.5 KFM23617.1 - 6.5 7.0 8.1 7.4 6.8 2.9 2.1 2 0 0 2 2 2 0 Small metal-binding protein DUF883 PF05957.13 KFM23617.1 - 8.4 7.1 11.6 4.6 7.9 0.2 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF948 PF06103.11 KFM23617.1 - 10 6.5 7.1 54 4.1 0.0 3.6 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Seipin PF06775.14 KFM23618.1 - 3.7e-08 33.7 0.0 5.5e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) HCV_NS4a PF01006.20 KFM23618.1 - 0.072 12.8 0.4 0.072 12.8 0.4 1.8 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein NS4a LMBR1 PF04791.16 KFM23620.1 - 4.4e-70 237.0 13.6 4.3e-67 227.2 13.6 2.0 1 1 0 1 1 1 1 LMBR1-like membrane protein PAP_assoc PF03828.19 KFM23622.1 - 4.3e-19 68.5 0.0 9.4e-19 67.4 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KFM23622.1 - 7.8e-06 26.1 0.0 1.4e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_central PF04928.17 KFM23622.1 - 0.00043 19.3 0.0 0.12 11.4 0.0 2.4 3 0 0 3 3 3 2 Poly(A) polymerase central domain FAM76 PF16046.5 KFM23623.1 - 1.9 7.8 22.5 0.88 8.9 12.1 2.8 2 2 0 2 2 2 0 FAM76 protein Coa1 PF08695.10 KFM23624.1 - 0.0011 18.7 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 TIM21 PF08294.11 KFM23624.1 - 0.086 12.7 0.0 0.35 10.7 0.0 1.8 2 0 0 2 2 2 0 TIM21 TPR_1 PF00515.28 KFM23625.1 - 9e-05 22.1 3.6 9.9e-05 22.0 0.2 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFM23625.1 - 0.00037 20.4 7.7 0.0013 18.7 0.4 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFM23625.1 - 0.00061 19.8 0.6 0.0043 17.2 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFM23625.1 - 0.021 15.3 1.0 0.05 14.1 1.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFM23625.1 - 0.022 14.8 2.5 4.3 7.5 0.0 2.7 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.6 KFM23625.1 - 0.067 12.9 0.7 0.73 9.6 0.2 2.6 3 0 0 3 3 3 0 TPR repeat TPR_16 PF13432.6 KFM23625.1 - 4.7 7.9 11.2 0.14 12.8 4.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFM23625.1 - 5.8 8.0 8.8 1.3 10.0 0.5 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat ABC_membrane_2 PF06472.15 KFM23626.1 - 1.9e-63 214.4 0.5 2.4e-63 214.0 0.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KFM23626.1 - 1.4e-19 71.0 0.0 4.3e-19 69.4 0.0 1.9 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KFM23626.1 - 0.0017 17.8 0.0 0.083 12.3 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KFM23626.1 - 0.0032 17.2 0.1 0.0089 15.7 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KFM23626.1 - 0.006 16.4 0.0 0.0096 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KFM23626.1 - 0.023 15.1 0.4 0.12 12.8 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 KFM23626.1 - 0.038 14.5 0.0 0.08 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KFM23626.1 - 0.095 12.4 0.5 0.89 9.2 0.1 2.7 2 1 0 2 2 2 0 AAA domain AAA_8 PF12780.7 KFM23626.1 - 0.11 11.8 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 Gtr1_RagA PF04670.12 KFM23626.1 - 0.2 11.0 0.0 5.9 6.2 0.1 2.4 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region TUG-UBL1 PF11470.8 KFM23627.1 - 1.2e-13 51.0 0.0 1.9e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 TUG ubiquitin-like domain UBX PF00789.20 KFM23627.1 - 0.0012 19.0 0.0 0.0024 18.0 0.0 1.4 1 0 0 1 1 1 1 UBX domain WD40 PF00400.32 KFM23629.1 - 1.1e-21 76.7 14.5 0.00082 20.1 0.1 7.5 7 0 0 7 7 7 5 WD domain, G-beta repeat Methyltr_RsmB-F PF01189.17 KFM23629.1 - 2.3e-16 60.0 0.4 2e-10 40.6 0.1 2.6 3 0 0 3 3 3 2 16S rRNA methyltransferase RsmB/F ANAPC4_WD40 PF12894.7 KFM23629.1 - 2.2e-07 31.1 0.1 1.1 9.5 0.0 5.3 4 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KFM23629.1 - 0.41 10.6 1.3 6.1 6.9 0.0 3.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Pheromone PF08015.11 KFM23629.1 - 7.2 7.7 6.8 48 5.1 0.1 3.2 2 1 0 2 2 2 0 Fungal mating-type pheromone Pro_isomerase PF00160.21 KFM23630.1 - 4.5e-24 85.5 0.0 2e-21 76.9 0.0 2.1 1 1 1 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Gly_transf_sug PF04488.15 KFM23631.1 - 2e-20 73.2 0.0 3.7e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 KFM23631.1 - 0.024 13.9 2.5 0.33 10.2 0.5 2.2 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain RNA_pol_Rpc4 PF05132.14 KFM23633.1 - 6.1 7.3 11.2 21 5.5 0.2 2.1 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF4701 PF15773.5 KFM23634.1 - 0.037 13.0 0.2 0.05 12.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4701) ERG4_ERG24 PF01222.17 KFM23635.1 - 4.3e-134 447.5 0.1 7.6e-134 446.7 0.1 1.4 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KFM23635.1 - 1.1e-08 34.8 0.1 2.3e-08 33.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 KFM23635.1 - 4.2e-05 23.9 0.0 0.00015 22.1 0.0 1.9 1 0 0 1 1 1 1 Phospholipid methyltransferase Cytochrom_C_asm PF01578.20 KFM23635.1 - 0.0065 16.3 0.2 0.027 14.3 0.1 2.0 1 1 1 2 2 2 1 Cytochrome C assembly protein Steroid_dh PF02544.16 KFM23635.1 - 0.042 13.8 0.1 0.074 13.0 0.1 1.4 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 KFM23635.1 - 0.067 13.6 0.4 0.19 12.2 0.0 1.9 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Aldedh PF00171.22 KFM23636.1 - 1.7e-275 913.7 0.0 3.1e-156 520.5 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family DUF742 PF05331.11 KFM23636.1 - 0.0026 17.6 0.0 3.8 7.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF742) IF2_N PF04760.15 KFM23636.1 - 0.064 13.1 0.4 1.3e+02 2.5 0.0 4.6 6 0 0 6 6 6 0 Translation initiation factor IF-2, N-terminal region YihI PF04220.12 KFM23636.1 - 0.069 12.9 0.7 5.9 6.6 0.2 2.4 2 0 0 2 2 2 0 Der GTPase activator (YihI) Elong-fact-P_C PF09285.11 KFM23636.1 - 0.073 12.8 0.2 21 4.9 0.0 2.6 2 0 0 2 2 2 0 Elongation factor P, C-terminal Sigma70_r1_1 PF03979.14 KFM23636.1 - 0.35 10.9 3.8 7.5 6.7 0.3 2.4 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 ISN1 PF06437.11 KFM23637.1 - 5.8e-93 312.0 0.0 7.4e-93 311.7 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Hydrolase_3 PF08282.12 KFM23637.1 - 0.094 12.4 0.0 7.9 6.1 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFM23637.1 - 0.11 12.8 1.0 13 6.1 0.2 2.8 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Raf1_N PF18578.1 KFM23638.1 - 1.4e-25 89.8 0.0 2.2e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 Rubisco accumulation factor 1 alpha helical domain Raf1_HTH PF18579.1 KFM23638.1 - 3.1e-17 62.0 0.1 5.8e-17 61.1 0.1 1.5 1 0 0 1 1 1 1 Rubisco accumulation factor 1 helix turn helix domain RuBisCo_chap_C PF18087.1 KFM23638.1 - 1.4e-10 41.0 0.0 2.1e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Rubisco Assembly chaperone C-terminal domain Prefoldin_2 PF01920.20 KFM23639.1 - 7.5e-19 67.7 3.8 8.8e-19 67.4 3.8 1.1 1 0 0 1 1 1 1 Prefoldin subunit tRNA-synt_2b PF00587.25 KFM23640.1 - 2.9e-20 73.0 0.0 4.6e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) ProRS-C_1 PF09180.11 KFM23640.1 - 3.1e-17 62.5 0.0 5.1e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 KFM23640.1 - 5.3e-08 32.9 0.0 1.3e-07 31.7 0.0 1.6 1 1 0 1 1 1 1 Anticodon binding domain Transketolase_N PF00456.21 KFM23641.1 - 1.5e-151 504.1 0.1 3.4e-151 502.9 0.1 1.5 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KFM23641.1 - 2e-38 131.9 0.1 3.2e-38 131.2 0.1 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KFM23641.1 - 1.1e-11 44.7 0.0 2.6e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.20 KFM23641.1 - 0.0061 15.5 0.0 0.0098 14.9 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component PGM_PMM_I PF02878.16 KFM23642.1 - 1.2e-18 67.2 0.1 3.7e-08 33.2 0.0 2.7 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 KFM23642.1 - 2.1e-11 43.8 1.2 5.8e-11 42.4 1.2 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 KFM23642.1 - 7.6e-06 26.1 0.0 0.00011 22.4 0.0 2.3 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III DNA_binding_1 PF01035.20 KFM23644.1 - 4.3e-13 49.2 0.1 8.2e-13 48.3 0.1 1.5 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Lipase_3 PF01764.25 KFM23645.1 - 0.0002 21.2 0.0 0.00047 20.0 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 KFM23645.1 - 0.052 13.3 0.0 0.079 12.7 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DNA_pol_A PF00476.20 KFM23646.1 - 3.7e-69 233.6 0.0 7.5e-68 229.3 0.0 2.3 2 1 0 2 2 2 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 KFM23646.1 - 1.5e-09 37.8 0.0 5.4e-09 36.0 0.0 1.9 1 1 0 1 1 1 1 3'-5' exonuclease Evr1_Alr PF04777.13 KFM23648.1 - 9.8e-20 70.9 0.1 2e-19 69.9 0.1 1.5 1 0 0 1 1 1 1 Erv1 / Alr family Thioredoxin PF00085.20 KFM23648.1 - 9.5e-19 67.3 0.0 1.8e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KFM23648.1 - 0.00033 20.9 0.0 0.03 14.7 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 KFM23648.1 - 0.00058 19.8 0.0 0.0014 18.6 0.0 1.6 2 0 0 2 2 2 1 AhpC/TSA family OST3_OST6 PF04756.13 KFM23648.1 - 0.00079 18.9 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 KFM23648.1 - 0.0015 18.7 0.1 0.0034 17.5 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 KFM23648.1 - 0.012 15.5 0.0 0.017 14.9 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 KFM23648.1 - 0.078 13.4 0.1 0.2 12.1 0.1 1.7 1 1 0 1 1 1 0 Thioredoxin-like domain NDUFA12 PF05071.16 KFM23649.1 - 1.9e-10 41.5 0.1 2.3e-10 41.2 0.1 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PRP21_like_P PF12230.8 KFM23650.1 - 9.3e-30 104.1 0.0 3.3e-16 59.8 0.0 2.3 1 1 1 2 2 2 2 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 KFM23650.1 - 8.3e-19 67.3 0.2 4.1e-13 49.1 0.2 2.3 1 1 1 2 2 2 2 Surp module ubiquitin PF00240.23 KFM23650.1 - 2.4e-07 30.4 0.0 3.7e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family WBS28 PF15164.6 KFM23652.1 - 0.0043 16.4 0.2 0.0075 15.6 0.2 1.5 1 0 0 1 1 1 1 Williams-Beuren syndrome chromosomal region 28 protein homologue Mem_trans PF03547.18 KFM23652.1 - 0.069 11.5 0.0 0.09 11.1 0.0 1.1 1 0 0 1 1 1 0 Membrane transport protein LPP20 PF02169.16 KFM23652.1 - 0.096 13.0 0.9 0.2 12.1 0.9 1.5 1 0 0 1 1 1 0 LPP20 lipoprotein PCMT PF01135.19 KFM23654.1 - 1.2e-39 136.2 0.0 2.1e-39 135.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) U-box PF04564.15 KFM23654.1 - 4.6e-11 42.7 0.0 1.6e-10 41.0 0.0 2.0 2 0 0 2 2 2 1 U-box domain PrmA PF06325.13 KFM23654.1 - 4.6e-09 36.1 0.2 7.9e-09 35.3 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) BTB PF00651.31 KFM23654.1 - 7.2e-07 29.4 0.0 1.4e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain MTS PF05175.14 KFM23654.1 - 7.6e-07 28.8 0.6 1.7e-06 27.7 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KFM23654.1 - 8e-06 26.5 0.1 3.9e-05 24.3 0.1 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM23654.1 - 2.1e-05 24.4 0.0 4.2e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain AviRa PF11599.8 KFM23654.1 - 0.00025 20.6 0.6 0.0058 16.1 0.1 2.2 2 0 0 2 2 2 1 RRNA methyltransferase AviRa CMAS PF02353.20 KFM23654.1 - 0.00033 20.1 0.0 0.00061 19.2 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 KFM23654.1 - 0.0012 18.8 0.0 0.0025 17.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM23654.1 - 0.0019 18.1 0.0 0.0039 17.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 KFM23654.1 - 0.0045 16.7 0.0 0.0073 16.0 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_11 PF08241.12 KFM23654.1 - 0.0045 17.6 0.1 0.023 15.3 0.1 2.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFM23654.1 - 0.0047 16.3 0.0 0.008 15.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family BACK PF07707.15 KFM23654.1 - 0.0051 16.9 0.0 0.026 14.6 0.0 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch DOT1 PF08123.13 KFM23654.1 - 0.0076 15.8 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Arm PF00514.23 KFM23654.1 - 0.022 14.8 1.4 0.92 9.6 0.2 3.9 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat FtsJ PF01728.19 KFM23654.1 - 0.042 14.0 0.0 0.14 12.3 0.1 1.8 2 0 0 2 2 1 0 FtsJ-like methyltransferase Methyltransf_18 PF12847.7 KFM23654.1 - 0.17 11.8 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Adaptin_N PF01602.20 KFM23655.1 - 1.4e-31 109.7 0.0 1.5e-27 96.4 0.0 2.4 1 1 1 2 2 2 2 Adaptin N terminal region HEAT_2 PF13646.6 KFM23655.1 - 0.012 16.0 0.6 0.012 16.0 0.6 3.6 3 1 0 3 3 3 0 HEAT repeats VPS28 PF03997.12 KFM23656.1 - 4.4e-62 209.1 0.0 5.4e-62 208.8 0.0 1.1 1 0 0 1 1 1 1 VPS28 protein ACP_PD PF04336.12 KFM23656.1 - 0.1 13.0 0.0 0.25 11.8 0.0 1.7 1 0 0 1 1 1 0 Acyl carrier protein phosphodiesterase Phosphodiest PF01663.22 KFM23657.1 - 6.1e-06 26.1 0.1 1.1e-05 25.2 0.1 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Ubie_methyltran PF01209.18 KFM23658.1 - 2.9e-50 170.8 0.0 3.3e-50 170.6 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 KFM23658.1 - 3.3e-21 75.8 0.0 5.4e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFM23658.1 - 3.7e-19 69.2 0.0 6.2e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM23658.1 - 9.4e-16 58.0 0.0 1.2e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM23658.1 - 5.9e-12 46.2 0.0 8.6e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM23658.1 - 8.7e-11 41.9 0.0 1.1e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KFM23658.1 - 5.5e-06 26.3 0.0 8.4e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 KFM23658.1 - 0.00031 20.4 0.0 0.0011 18.6 0.0 1.7 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 KFM23658.1 - 0.0036 17.3 0.0 0.0051 16.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KFM23658.1 - 0.0047 17.1 0.0 0.0056 16.8 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_8 PF05148.15 KFM23658.1 - 0.058 13.2 0.0 0.13 12.1 0.0 1.5 1 1 1 2 2 2 0 Hypothetical methyltransferase UPF0020 PF01170.18 KFM23658.1 - 0.064 12.9 0.0 2.1 8.0 0.0 2.1 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 MTS PF05175.14 KFM23658.1 - 0.066 12.8 0.0 0.099 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltr_RsmB-F PF01189.17 KFM23658.1 - 0.085 12.5 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F GCD14 PF08704.10 KFM23658.1 - 0.087 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit LIAS_N PF16881.5 KFM23659.1 - 3e-20 72.7 0.0 1.1e-19 70.9 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 KFM23659.1 - 4.5e-18 66.2 0.0 1.3e-17 64.7 0.0 1.8 1 1 0 1 1 1 1 Radical SAM superfamily DeoC PF01791.9 KFM23659.1 - 0.038 13.6 0.1 0.084 12.5 0.0 1.5 2 0 0 2 2 2 0 DeoC/LacD family aldolase DUF2748 PF10871.8 KFM23659.1 - 0.22 10.1 0.0 0.32 9.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2748) U3_assoc_6 PF08640.11 KFM23660.1 - 1.2e-22 79.8 0.1 3.8e-22 78.1 0.2 1.8 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 PWI PF01480.17 KFM23661.1 - 2.4e-30 104.7 0.3 5.2e-30 103.6 0.0 1.7 2 0 0 2 2 2 1 PWI domain Atg14 PF10186.9 KFM23661.1 - 0.081 12.0 2.6 0.1 11.7 2.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Sec7 PF01369.20 KFM23662.1 - 8.7e-71 237.4 0.0 1.7e-70 236.4 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KFM23662.1 - 4.9e-35 120.8 0.0 4.8e-34 117.6 0.0 2.4 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KFM23662.1 - 3.4e-31 106.9 0.1 2.7e-30 104.1 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) DCB PF16213.5 KFM23662.1 - 3.6e-18 65.8 0.0 1.2e-16 60.9 0.0 2.7 2 1 1 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 Mon2_C PF16206.5 KFM23662.1 - 1.8e-08 33.1 0.0 2.7e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 C-terminal region of Mon2 protein HalOD1 PF18545.1 KFM23662.1 - 0.0023 18.2 0.1 0.02 15.1 0.0 2.6 2 0 0 2 2 2 1 Halobacterial output domain 1 HEAT PF02985.22 KFM23662.1 - 1.8 9.0 7.0 15 6.2 0.1 4.5 4 0 0 4 4 4 0 HEAT repeat RCC1 PF00415.18 KFM23663.1 - 1.9e-13 50.8 8.7 3.2e-09 37.3 0.3 5.1 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFM23663.1 - 7.1e-08 32.1 11.4 0.00018 21.2 1.9 3.9 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat ABC_membrane_2 PF06472.15 KFM23665.1 - 1.9e-25 89.8 0.0 2.9e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KFM23665.1 - 2.4e-17 63.8 0.0 4e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter MMADHC PF10229.9 KFM23665.1 - 5.6e-07 29.6 0.0 8.5e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type D protein AAA_21 PF13304.6 KFM23665.1 - 6.4e-06 26.2 0.3 0.00011 22.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFM23665.1 - 0.00027 20.6 0.0 0.00063 19.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KFM23665.1 - 0.0024 18.3 0.2 0.016 15.6 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 KFM23665.1 - 0.0041 17.6 0.0 0.0065 17.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KFM23665.1 - 0.0072 15.9 8.5 0.2 11.2 0.2 4.0 4 0 0 4 4 4 1 AAA domain AAA_27 PF13514.6 KFM23665.1 - 0.018 14.6 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KFM23665.1 - 0.021 14.7 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase Mg_chelatase PF01078.21 KFM23665.1 - 0.089 12.2 0.2 0.17 11.3 0.2 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KFM23665.1 - 0.1 13.2 0.0 0.17 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KFM23665.1 - 0.17 12.0 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase UQ_con PF00179.26 KFM23666.1 - 3.7e-11 42.8 0.0 5.9e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFM23666.1 - 0.15 12.4 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 RWD domain DUF2076 PF09849.9 KFM23666.1 - 1.7 8.7 3.2 2.2 8.3 3.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Cpn60_TCP1 PF00118.24 KFM23667.1 - 4.4e-162 540.1 0.2 5.5e-162 539.8 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Band_7 PF01145.25 KFM23669.1 - 1.5e-25 90.2 3.1 2.6e-25 89.5 3.1 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family Med2 PF11214.8 KFM23669.1 - 0.01 15.9 0.7 0.018 15.2 0.7 1.4 1 0 0 1 1 1 0 Mediator complex subunit 2 Gpr1_Fun34_YaaH PF01184.19 KFM23671.1 - 7.2e-36 123.7 19.1 1.1e-35 123.1 19.1 1.2 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF2206 PF09971.9 KFM23671.1 - 0.0082 14.9 1.4 0.013 14.3 1.4 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2206) DUF1774 PF08611.10 KFM23671.1 - 3.6 8.0 7.0 0.71 10.2 3.4 1.7 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1774) SlyX PF04102.12 KFM23672.1 - 0.016 15.8 11.9 0.045 14.4 1.0 3.9 2 1 0 3 3 3 0 SlyX DUF3584 PF12128.8 KFM23672.1 - 0.026 12.1 3.6 0.034 11.7 3.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Takusan PF04822.13 KFM23672.1 - 0.14 12.1 0.4 0.27 11.2 0.4 1.5 1 0 0 1 1 1 0 Takusan Herpes_UL25 PF01499.16 KFM23672.1 - 0.23 9.9 4.8 0.34 9.4 4.8 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF4407 PF14362.6 KFM23672.1 - 0.98 8.7 11.9 1.7 7.9 11.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3138 PF11336.8 KFM23672.1 - 1.9 7.0 10.5 0.44 9.1 5.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) Mt_ATP-synt_B PF05405.14 KFM23672.1 - 5.4 6.6 6.2 8.7 5.9 6.2 1.2 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Lipase_3 PF01764.25 KFM23674.1 - 5.3e-13 49.0 0.0 7.7e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) BON PF04972.17 KFM23674.1 - 0.028 14.7 0.0 0.07 13.4 0.0 1.6 1 0 0 1 1 1 0 BON domain PGAP1 PF07819.13 KFM23674.1 - 0.038 13.7 0.0 0.059 13.1 0.0 1.1 1 0 0 1 1 1 0 PGAP1-like protein Hydrolase_4 PF12146.8 KFM23674.1 - 0.14 11.4 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF2048 PF09752.9 KFM23675.1 - 3.9e-61 207.1 0.0 2.9e-42 145.0 0.0 2.0 2 0 0 2 2 2 2 Abhydrolase domain containing 18 TPR_14 PF13428.6 KFM23675.1 - 0.27 12.2 4.8 1.6 9.8 1.1 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat CTP_transf_3 PF02348.19 KFM23676.1 - 1.1e-52 179.1 0.0 1.5e-52 178.7 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 KFM23676.1 - 5.9e-11 43.0 3.9 6.7e-11 42.8 0.5 2.3 2 1 0 2 2 2 1 MobA-like NTP transferase domain IspD PF01128.19 KFM23676.1 - 0.00011 22.0 0.1 0.00092 19.0 0.0 2.0 2 0 0 2 2 2 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase ADH_zinc_N PF00107.26 KFM23676.1 - 0.00054 19.9 0.2 0.0015 18.5 0.1 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase DUF2064 PF09837.9 KFM23676.1 - 0.031 14.1 0.3 0.056 13.3 0.3 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2064) rve PF00665.26 KFM23676.1 - 0.15 12.2 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain TPR_19 PF14559.6 KFM23677.1 - 4.4e-12 46.3 11.3 3.1e-05 24.4 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFM23677.1 - 3.8e-09 36.0 8.1 0.048 13.8 0.1 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFM23677.1 - 5.2e-07 30.0 25.3 0.018 15.9 2.2 6.3 4 2 4 8 8 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFM23677.1 - 5.2e-07 29.9 5.5 0.019 15.2 0.3 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFM23677.1 - 1e-06 28.3 7.2 0.29 11.2 0.3 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFM23677.1 - 1.9e-06 27.6 0.9 0.72 10.2 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFM23677.1 - 5.5e-06 26.9 29.7 3e-05 24.6 0.1 5.5 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFM23677.1 - 6.9e-06 25.6 6.0 0.0019 17.8 0.0 4.5 3 1 1 4 4 4 1 TPR repeat TPR_17 PF13431.6 KFM23677.1 - 4.7e-05 23.5 0.4 0.92 10.0 0.0 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFM23677.1 - 8.5e-05 22.2 2.4 0.89 9.5 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 KFM23677.1 - 0.00031 20.0 1.8 0.046 12.9 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 KFM23677.1 - 0.0014 19.0 31.8 0.0092 16.5 0.7 6.6 7 0 0 7 7 5 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 KFM23677.1 - 0.0014 18.2 0.1 0.44 10.2 0.1 2.5 2 0 0 2 2 2 1 Bacterial type III secretion protein (HrpB1_HrpK) DUF3856 PF12968.7 KFM23677.1 - 0.0034 17.5 0.2 0.48 10.5 0.1 2.6 2 0 0 2 2 2 1 Domain of Unknown Function (DUF3856) ANAPC3 PF12895.7 KFM23677.1 - 0.0072 16.5 0.2 4.4 7.6 0.0 3.0 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 KFM23677.1 - 0.052 13.6 0.1 19 5.4 0.0 2.7 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat A_thal_3526 PF09713.10 KFM23677.1 - 0.23 11.7 0.0 24 5.3 0.0 3.0 3 0 0 3 3 3 0 Plant protein 1589 of unknown function (A_thal_3526) TPR_10 PF13374.6 KFM23677.1 - 0.28 11.1 15.2 6.9 6.7 3.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFM23677.1 - 0.7 10.7 6.7 5.1 8.0 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 KFM23677.1 - 0.81 9.9 8.9 3.7 7.7 0.0 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat ABC1 PF03109.16 KFM23679.1 - 3.4e-31 107.9 0.0 7.5e-31 106.8 0.0 1.6 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 KFM23679.1 - 4.4e-07 29.5 0.0 0.00035 20.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain WaaY PF06176.11 KFM23679.1 - 0.0066 16.1 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.23 KFM23679.1 - 0.01 15.8 0.3 0.01 15.8 0.3 3.0 3 1 1 4 4 4 0 Phosphotransferase enzyme family DUF4012 PF13196.6 KFM23679.1 - 0.018 15.5 0.0 0.44 11.0 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4012) CBF PF03914.17 KFM23680.1 - 7.5e-48 162.8 0.0 7.3e-47 159.6 0.0 2.4 2 0 0 2 2 2 1 CBF/Mak21 family Adaptin_N PF01602.20 KFM23680.1 - 0.021 13.4 0.1 0.43 9.1 0.0 2.0 2 0 0 2 2 2 0 Adaptin N terminal region Cnd1 PF12717.7 KFM23680.1 - 0.24 11.4 0.2 0.58 10.2 0.1 1.6 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Pep1_7 PF17232.2 KFM23680.1 - 3.1 8.3 5.3 1.7 9.1 2.6 2.1 2 0 0 2 2 2 0 Elicitor peptide 1-7 HlyIII PF03006.20 KFM23681.1 - 1.5e-58 198.2 16.7 8.3e-58 195.7 16.7 1.9 1 1 0 1 1 1 1 Haemolysin-III related Ribosomal_L27 PF01016.19 KFM23684.1 - 1.2e-33 115.0 2.8 1.6e-33 114.6 2.8 1.2 1 0 0 1 1 1 1 Ribosomal L27 protein Cnd2 PF05786.14 KFM23685.1 - 3.6e-91 307.1 0.1 3.3e-60 204.7 0.0 3.8 2 2 1 3 3 3 2 Condensin complex subunit 2 CAP_C PF08603.11 KFM23687.1 - 1.3e-50 171.1 0.0 1.8e-50 170.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal CAP_N PF01213.19 KFM23687.1 - 2.8e-48 165.0 6.0 3.3e-37 128.7 0.2 2.1 1 1 1 2 2 2 2 Adenylate cyclase associated (CAP) N terminal PIN_10 PF18478.1 KFM23687.1 - 0.14 12.4 0.2 2.2 8.6 0.0 2.3 2 0 0 2 2 2 0 PIN like domain TBCC PF07986.12 KFM23687.1 - 0.16 11.7 0.6 0.25 11.1 0.6 1.3 1 0 0 1 1 1 0 Tubulin binding cofactor C Proteasome PF00227.26 KFM23688.1 - 6.7e-58 195.3 0.0 1.1e-57 194.7 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KFM23688.1 - 1.1e-12 47.3 0.1 3e-12 46.0 0.1 1.8 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Codanin-1_C PF15296.6 KFM23688.1 - 3.3e-06 27.2 0.0 5.6e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Codanin-1 C-terminus MatE PF01554.18 KFM23690.1 - 3.9e-11 42.9 25.6 1.6e-08 34.4 0.7 2.9 2 1 1 3 3 3 2 MatE Polysacc_synt_C PF14667.6 KFM23690.1 - 9.2e-07 29.0 8.2 9.2e-07 29.0 8.2 3.1 3 1 0 3 3 3 2 Polysaccharide biosynthesis C-terminal domain Peptidase_M3 PF01432.20 KFM23691.1 - 5.1e-51 174.4 0.0 7.9e-51 173.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Argos PF11581.8 KFM23691.1 - 0.026 14.6 0.0 0.12 12.4 0.0 1.9 2 0 0 2 2 2 0 Antagonist of EGFR signalling, Argos Amino_oxidase PF01593.24 KFM23692.1 - 4.6e-60 204.2 0.0 5.4e-60 204.0 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFM23692.1 - 1.5e-15 57.2 0.1 3.5e-15 56.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFM23692.1 - 5.6e-06 26.2 0.1 1.9e-05 24.4 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KFM23692.1 - 7.4e-05 22.3 0.1 0.00019 20.9 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase MCRA PF06100.11 KFM23692.1 - 0.00022 20.2 0.0 0.02 13.7 0.0 2.1 2 0 0 2 2 2 1 MCRA family Pyr_redox_2 PF07992.14 KFM23692.1 - 0.00051 19.4 0.0 0.0015 17.9 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFM23692.1 - 0.00066 19.0 0.1 0.0014 17.9 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 KFM23692.1 - 0.00086 18.5 0.1 0.0024 17.0 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KFM23692.1 - 0.00087 18.1 0.2 0.0019 16.9 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 KFM23692.1 - 0.0075 16.8 0.1 0.022 15.3 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KFM23692.1 - 0.0098 15.2 0.0 0.039 13.3 0.0 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 KFM23692.1 - 0.029 14.3 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.22 KFM23692.1 - 0.071 12.2 0.1 0.1 11.6 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF21 PF01595.20 KFM23693.1 - 1.4e-25 90.0 2.3 5e-25 88.2 2.3 1.8 1 1 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KFM23693.1 - 4.7e-07 30.1 3.1 0.023 15.2 0.6 3.7 3 0 0 3 3 3 3 CBS domain Hydrolase PF00702.26 KFM23694.1 - 3.4e-05 24.2 0.2 0.00072 19.9 0.2 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KFM23694.1 - 9.3e-05 22.6 0.0 0.25 11.4 0.0 2.3 1 1 1 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFM23694.1 - 0.023 14.7 0.0 0.053 13.6 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like Hydrolase_6 PF13344.6 KFM23694.1 - 0.029 14.5 0.0 0.19 11.9 0.0 2.2 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Na_H_Exchanger PF00999.21 KFM23696.1 - 1.1e-30 106.8 46.6 1.4e-30 106.4 46.6 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF1350 PF07082.11 KFM23697.1 - 1.8e-51 174.9 0.2 2.6e-49 167.8 0.2 2.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1350) Abhydrolase_6 PF12697.7 KFM23697.1 - 0.00073 20.2 3.8 0.00073 20.2 3.8 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 KFM23697.1 - 0.021 15.0 0.4 0.049 13.7 0.2 1.7 2 0 0 2 2 2 0 Thioesterase domain Hydrolase_4 PF12146.8 KFM23697.1 - 0.033 13.5 0.0 0.058 12.7 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 FUSC_2 PF13515.6 KFM23698.1 - 3.9e-10 39.9 12.9 3.9e-10 39.9 12.9 3.4 3 0 0 3 3 3 1 Fusaric acid resistance protein-like FUSC PF04632.12 KFM23698.1 - 1.2e-09 37.3 13.5 1.2e-09 37.3 13.5 3.4 3 2 0 3 3 3 1 Fusaric acid resistance protein family ALMT PF11744.8 KFM23698.1 - 4.1e-07 29.2 10.8 4.1e-07 29.2 10.8 2.2 2 0 0 2 2 2 1 Aluminium activated malate transporter ArAE_2_N PF10337.9 KFM23698.1 - 0.0055 15.8 10.1 0.027 13.5 2.8 2.6 2 0 0 2 2 2 2 Putative ER transporter, 6TM, N-terminal FUSC PF04632.12 KFM23699.1 - 1.9e-10 40.0 12.4 1.9e-10 40.0 12.4 3.4 3 0 0 3 3 3 2 Fusaric acid resistance protein family ALMT PF11744.8 KFM23699.1 - 1.3e-08 34.2 8.6 1e-07 31.2 8.2 2.0 2 0 0 2 2 2 1 Aluminium activated malate transporter FUSC_2 PF13515.6 KFM23699.1 - 1.9e-08 34.5 11.7 1.9e-08 34.5 11.7 3.0 2 0 0 2 2 2 1 Fusaric acid resistance protein-like DUF3021 PF11457.8 KFM23699.1 - 4.7 7.6 12.3 0.085 13.2 1.5 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) KH_1 PF00013.29 KFM23701.1 - 2.7e-44 148.9 0.0 3.6e-15 55.5 0.5 3.1 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KFM23701.1 - 9.7e-12 44.6 0.4 0.0021 17.9 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KFM23701.1 - 1.1e-07 31.6 0.6 0.047 13.6 0.3 3.3 3 0 0 3 3 3 2 KH domain KH_5 PF13184.6 KFM23701.1 - 0.0021 18.1 5.7 0.6 10.2 1.0 3.2 3 0 0 3 3 3 2 NusA-like KH domain Pur_ac_phosph_N PF16656.5 KFM23703.1 - 2.2e-20 73.0 2.1 3.3e-20 72.4 0.1 2.3 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 KFM23703.1 - 2e-08 35.0 0.8 4.1e-08 34.0 0.8 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase fn3_PAP PF17808.1 KFM23703.1 - 3.4e-05 23.9 0.2 0.00015 21.9 0.2 2.1 1 1 0 1 1 1 1 Fn3-like domain from Purple Acid Phosphatase Metallophos_C PF14008.6 KFM23703.1 - 0.00024 21.9 0.0 0.00082 20.2 0.0 2.0 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C fn3 PF00041.21 KFM23703.1 - 0.49 10.8 2.8 1.2 9.5 0.4 2.6 2 1 0 2 2 2 0 Fibronectin type III domain TruB_C PF09142.11 KFM23704.1 - 0.05 13.4 7.1 0.29 11.0 1.1 3.1 2 1 1 3 3 3 0 tRNA Pseudouridine synthase II, C terminal TPIP1 PF15338.6 KFM23704.1 - 0.097 12.7 4.1 5.6 7.1 0.2 2.3 1 1 0 2 2 2 0 p53-regulated apoptosis-inducing protein 1 Pkinase PF00069.25 KFM23705.1 - 2.3e-64 217.3 0.0 3e-64 216.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM23705.1 - 4.6e-34 117.9 0.0 6.4e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM23705.1 - 7.9e-08 31.9 0.0 1.8e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFM23705.1 - 0.0011 18.0 0.1 0.0017 17.4 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 KFM23705.1 - 0.14 11.2 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 B12-binding_2 PF02607.17 KFM23705.1 - 1.8 9.1 6.8 0.17 12.3 2.1 1.8 2 0 0 2 2 2 0 B12 binding domain PhoD PF09423.10 KFM23706.1 - 1.4e-06 27.6 0.0 1.5e-05 24.2 0.0 2.0 1 1 1 2 2 2 1 PhoD-like phosphatase Peptidase_M73 PF12389.8 KFM23707.1 - 0.015 15.1 0.3 0.02 14.7 0.3 1.1 1 0 0 1 1 1 0 Camelysin metallo-endopeptidase HlyIII PF03006.20 KFM23707.1 - 0.024 14.3 6.2 0.032 13.9 6.2 1.1 1 0 0 1 1 1 0 Haemolysin-III related DUF4293 PF14126.6 KFM23707.1 - 0.25 11.6 3.1 0.34 11.2 3.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) DUF2976 PF11190.8 KFM23707.1 - 0.47 10.3 5.5 0.29 11.0 0.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2976) S1FA PF04689.13 KFM23707.1 - 4.5 7.5 4.3 18 5.5 0.4 2.4 2 1 0 2 2 2 0 DNA binding protein S1FA DUF647 PF04884.14 KFM23709.1 - 1.6e-56 191.6 6.5 2.9e-56 190.8 6.5 1.4 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis VacA2 PF03077.14 KFM23709.1 - 3.6 7.5 7.0 0.21 11.5 1.6 1.7 2 0 0 2 2 2 0 Putative vacuolating cytotoxin BTB PF00651.31 KFM23710.1 - 4.5e-19 68.7 0.0 1.3e-18 67.3 0.0 1.7 1 1 1 2 2 2 1 BTB/POZ domain DUF2339 PF10101.9 KFM23711.1 - 0.0074 14.9 1.6 0.0091 14.6 1.6 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) Methyltransf_16 PF10294.9 KFM23712.1 - 4.9e-29 101.3 0.0 5.5e-29 101.1 0.0 1.0 1 0 0 1 1 1 1 Lysine methyltransferase MTP18 PF10558.9 KFM23713.1 - 9.1e-11 42.0 3.1 9.5e-09 35.4 0.5 2.7 1 1 1 2 2 2 2 Mitochondrial 18 KDa protein (MTP18) Amino_oxidase PF01593.24 KFM23715.1 - 0.0002 20.8 0.0 0.0039 16.5 0.0 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DUF4794 PF16042.5 KFM23715.1 - 0.11 13.5 0.0 0.22 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4794) DAP3 PF10236.9 KFM23716.1 - 3.3e-22 79.1 0.0 1.3e-17 64.0 0.0 2.8 2 1 0 2 2 2 2 Mitochondrial ribosomal death-associated protein 3 T2SSE PF00437.20 KFM23716.1 - 0.001 18.2 0.1 0.078 12.0 0.0 2.1 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.6 KFM23716.1 - 0.002 18.5 0.3 0.0036 17.7 0.3 1.4 1 0 0 1 1 1 1 AAA ATPase domain TrwB_AAD_bind PF10412.9 KFM23716.1 - 0.094 11.6 0.0 0.25 10.2 0.0 1.6 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Glyco_hydro_88 PF07470.13 KFM23716.1 - 0.13 11.3 0.1 0.17 10.9 0.1 1.1 1 0 0 1 1 1 0 Glycosyl Hydrolase Family 88 EccE PF11203.8 KFM23716.1 - 1.2 9.5 6.5 0.35 11.2 1.7 2.5 2 2 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE IlvC PF01450.19 KFM23718.1 - 6.5e-39 133.5 0.0 2.9e-30 105.4 0.0 2.3 2 0 0 2 2 2 2 Acetohydroxy acid isomeroreductase, catalytic domain IlvN PF07991.12 KFM23718.1 - 2.4e-32 111.8 0.2 4.7e-32 110.8 0.2 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain SET PF00856.28 KFM23719.1 - 6.8e-05 23.3 0.0 0.00044 20.7 0.0 2.0 2 0 0 2 2 2 1 SET domain Peptidase_S8 PF00082.22 KFM23720.1 - 2.5e-23 82.8 1.2 3.3e-23 82.4 1.2 1.0 1 0 0 1 1 1 1 Subtilase family zf-MYND PF01753.18 KFM23721.1 - 0.00032 20.7 8.1 0.00032 20.7 8.1 1.7 2 0 0 2 2 2 1 MYND finger HypA PF01155.19 KFM23721.1 - 0.076 13.0 0.8 0.15 12.1 0.1 1.8 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C6H2 PF15801.5 KFM23721.1 - 0.91 9.9 5.7 1.8 8.9 5.7 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding SPRR2 PF14820.6 KFM23721.1 - 2 8.6 11.0 0.13 12.4 4.5 2.3 2 0 0 2 2 2 0 Small proline-rich 2 Hist_deacetyl PF00850.19 KFM23722.1 - 2.1e-83 280.3 0.1 2.5e-83 280.1 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain FXR_C3 PF16097.5 KFM23723.1 - 5.5 7.8 9.8 25 5.7 2.9 3.2 1 1 1 2 2 2 0 Fragile X-related 1 protein C-terminal region 3 Cu_bind_like PF02298.17 KFM23725.1 - 0.084 12.9 0.3 16 5.6 0.0 2.4 2 1 0 2 2 2 0 Plastocyanin-like domain adh_short PF00106.25 KFM23726.1 - 6.1e-06 25.8 0.0 8.7e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Cu_bind_like PF02298.17 KFM23726.1 - 0.059 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Plastocyanin-like domain Copper-bind PF00127.20 KFM23726.1 - 0.18 12.3 0.0 0.47 10.9 0.0 1.6 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family ArsA_ATPase PF02374.15 KFM23727.1 - 5e-66 222.9 0.0 6.5e-66 222.6 0.0 1.1 1 0 0 1 1 1 1 Anion-transporting ATPase CCDC-167 PF15188.6 KFM23727.1 - 0.0043 17.3 0.5 0.31 11.4 0.1 2.3 2 0 0 2 2 2 2 Coiled-coil domain-containing protein 167 Nuf2 PF03800.14 KFM23730.1 - 4.6e-40 137.0 0.0 7.4e-40 136.3 0.0 1.4 1 0 0 1 1 1 1 Nuf2 family DHR10 PF18595.1 KFM23730.1 - 3.5e-15 56.1 18.9 3.5e-15 56.1 18.9 4.1 1 1 3 4 4 4 1 Designed helical repeat protein 10 domain ADIP PF11559.8 KFM23730.1 - 0.00015 21.9 3.9 0.00015 21.9 3.9 4.1 2 1 2 4 4 4 2 Afadin- and alpha -actinin-Binding YgaB PF14182.6 KFM23730.1 - 0.48 10.9 6.5 0.28 11.6 1.3 3.0 1 1 0 2 2 2 0 YgaB-like protein HALZ PF02183.18 KFM23730.1 - 0.99 9.7 7.0 7.1 6.9 1.0 3.8 3 1 1 4 4 4 0 Homeobox associated leucine zipper Med9 PF07544.13 KFM23730.1 - 3.1 8.0 12.1 0.2 11.8 1.3 3.5 2 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DEAD PF00270.29 KFM23731.1 - 4.6e-45 153.5 0.0 6.4e-45 153.1 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.6 KFM23731.1 - 1.9e-14 53.6 2.0 3.7e-14 52.7 1.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 KFM23731.1 - 5e-09 36.5 0.0 3.2e-08 33.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM23731.1 - 2.9e-05 24.1 0.0 4.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PrmC_N PF17827.1 KFM23731.1 - 0.1 13.2 1.3 0.36 11.5 1.3 2.0 1 1 0 1 1 1 0 PrmC N-terminal domain COX15-CtaA PF02628.15 KFM23734.1 - 2.8e-60 204.1 10.8 9.8e-58 195.7 2.5 2.2 1 1 1 2 2 2 2 Cytochrome oxidase assembly protein UBA PF00627.31 KFM23734.1 - 0.00062 19.6 2.1 0.0012 18.7 2.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Myb_DNA-binding PF00249.31 KFM23734.1 - 0.15 12.3 0.0 0.46 10.7 0.0 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF3172 PF11371.8 KFM23735.1 - 4.7e-57 191.6 0.1 5.5e-57 191.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3172) Nsp1_C PF05064.13 KFM23736.1 - 1.9e-16 59.9 0.5 3e-16 59.3 0.5 1.3 1 0 0 1 1 1 1 Nsp1-like C-terminal region APG6_N PF17675.1 KFM23736.1 - 0.0019 18.7 2.4 0.0032 18.0 2.4 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region HAUS-augmin3 PF14932.6 KFM23736.1 - 0.015 14.9 2.1 0.022 14.4 2.1 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Baculo_PEP_C PF04513.12 KFM23736.1 - 0.068 13.2 2.8 0.98 9.5 0.8 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF724 PF05266.14 KFM23736.1 - 0.095 12.5 0.3 0.12 12.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) COG2 PF06148.11 KFM23736.1 - 0.26 11.4 1.7 12 5.9 0.0 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Ribosomal_L32e PF01655.18 KFM23738.1 - 6.6e-47 158.4 0.7 7.8e-47 158.2 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 ING PF12998.7 KFM23739.1 - 6e-17 62.1 2.0 8.2e-17 61.7 2.0 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding YflT PF11181.8 KFM23739.1 - 0.1 13.1 0.0 2.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Heat induced stress protein YflT Nif11 PF07862.11 KFM23739.1 - 7.7 6.9 7.2 10 6.5 1.8 2.8 3 0 0 3 3 3 0 Nif11 domain Dzip-like_N PF13815.6 KFM23740.1 - 4.7e-13 49.1 0.0 6.5e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal BPL_LplA_LipB PF03099.19 KFM23741.1 - 4.8e-09 36.2 0.0 6.8e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family PDCD2_C PF04194.13 KFM23744.1 - 6.9e-27 94.6 0.0 1.2e-26 93.9 0.0 1.4 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain OrfB_Zn_ribbon PF07282.11 KFM23745.1 - 0.011 15.7 6.9 0.011 15.7 6.9 2.6 2 1 0 2 2 2 0 Putative transposase DNA-binding domain DUF460 PF04312.13 KFM23745.1 - 0.031 14.0 0.0 0.12 12.0 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF460) OTT_1508_deam PF14441.6 KFM23745.1 - 0.048 13.7 0.8 0.11 12.5 0.8 1.6 1 0 0 1 1 1 0 OTT_1508-like deaminase Ribosomal_L11 PF00298.19 KFM23746.1 - 2.8e-27 95.0 0.1 4.2e-27 94.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 KFM23746.1 - 1.1e-24 86.0 2.1 2.1e-24 85.1 2.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain WD40 PF00400.32 KFM23747.1 - 1.6e-14 54.0 2.3 0.041 14.8 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat PQQ_3 PF13570.6 KFM23747.1 - 0.0048 17.3 1.1 2.8 8.5 0.1 3.9 3 1 1 4 4 4 2 PQQ-like domain TLC PF03219.14 KFM23748.1 - 2.5e-84 283.8 2.0 1.2e-41 143.1 0.3 2.3 1 1 1 2 2 2 2 TLC ATP/ADP transporter DUF4131 PF13567.6 KFM23748.1 - 1.2 8.8 13.2 3.6 7.2 5.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) JAB PF01398.21 KFM23749.1 - 9.8e-23 80.4 0.1 1.6e-22 79.7 0.1 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KFM23749.1 - 3e-16 59.8 0.0 5.5e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UbiA PF01040.18 KFM23751.1 - 1.5e-48 165.4 27.5 2.7e-48 164.5 27.5 1.4 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF5337 PF17272.2 KFM23751.1 - 0.89 9.4 4.4 0.41 10.5 0.7 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5337) Pkinase PF00069.25 KFM23752.1 - 3.8e-44 151.0 0.0 5e-44 150.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM23752.1 - 2.1e-31 109.2 0.0 2.8e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFM23752.1 - 0.00071 18.5 0.0 0.0019 17.1 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase DUF2000 PF09391.10 KFM23752.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2000) OSR1_C PF12202.8 KFM23753.1 - 5.3e-06 26.6 0.0 8.6e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain Sua5_yciO_yrdC PF01300.18 KFM23754.1 - 1.7e-39 135.1 0.0 2.7e-39 134.5 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination Exo_endo_phos PF03372.23 KFM23754.1 - 1.1e-08 34.9 0.0 3.5e-08 33.3 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Amino_oxidase PF01593.24 KFM23754.1 - 4.4e-05 22.9 0.0 0.00011 21.7 0.0 1.6 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase peroxidase PF00141.23 KFM23755.1 - 3.5e-18 66.1 0.0 5.4e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Peroxidase RrnaAD PF00398.20 KFM23756.1 - 6.7e-63 212.2 0.0 8e-63 212.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KFM23756.1 - 1.3e-08 35.4 0.0 3.1e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFM23756.1 - 2.5e-06 28.1 0.0 5.1e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM23756.1 - 1.9e-05 25.3 0.0 5.6e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KFM23756.1 - 0.00039 20.2 0.0 0.00057 19.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NodS PF05401.11 KFM23756.1 - 0.0014 18.3 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_23 PF13489.6 KFM23756.1 - 0.0027 17.6 0.0 0.0038 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFM23756.1 - 0.016 14.8 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 KFM23756.1 - 0.025 14.0 0.0 0.06 12.8 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase Met_10 PF02475.16 KFM23756.1 - 0.025 14.3 0.0 0.038 13.7 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein PRMT5 PF05185.16 KFM23756.1 - 0.026 14.4 0.0 0.04 13.8 0.0 1.2 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Ubie_methyltran PF01209.18 KFM23756.1 - 0.037 13.4 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KFM23756.1 - 0.058 13.2 0.0 0.14 11.9 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain DREV PF05219.12 KFM23756.1 - 0.07 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase PPS_PS PF02006.16 KFM23756.1 - 0.098 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphopantothenate/pantothenate synthetase Methyltransf_2 PF00891.18 KFM23756.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain CMAS PF02353.20 KFM23756.1 - 0.23 10.7 0.0 0.34 10.2 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DnaJ PF00226.31 KFM23757.1 - 9.6e-12 44.9 0.6 5.8e-11 42.3 0.0 2.6 3 0 0 3 3 3 1 DnaJ domain Evr1_Alr PF04777.13 KFM23758.1 - 4.4e-21 75.2 0.0 5.5e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Erv1 / Alr family TRAPPC-Trs85 PF12739.7 KFM23758.1 - 0.16 10.9 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Ank_5 PF13857.6 KFM23759.1 - 1.4e-12 47.6 0.1 1.2e-08 35.1 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM23759.1 - 8.9e-12 45.4 0.0 1.1e-09 38.7 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KFM23759.1 - 2e-11 43.8 0.0 9.9e-08 32.1 0.0 3.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 KFM23759.1 - 9.1e-11 42.1 0.1 0.00063 20.3 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM23759.1 - 1.3e-07 31.3 0.0 1.7e-05 24.8 0.0 3.3 4 0 0 4 4 4 1 Ankyrin repeat TPR_1 PF00515.28 KFM23760.1 - 2.7e-12 45.9 2.5 1.3e-07 31.1 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFM23760.1 - 1e-09 37.8 3.8 4.1e-05 23.4 0.0 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFM23760.1 - 4.6e-06 26.4 2.3 0.00034 20.6 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFM23760.1 - 0.00018 21.3 1.2 0.022 14.8 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFM23760.1 - 0.00019 22.0 8.5 0.00019 22.0 8.5 5.2 3 2 2 5 5 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFM23760.1 - 0.00029 21.3 14.4 0.00084 19.8 0.7 4.5 3 2 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFM23760.1 - 0.00067 19.3 6.3 0.082 12.6 0.1 3.1 2 1 1 3 3 3 2 TPR repeat TPR_14 PF13428.6 KFM23760.1 - 0.00082 20.0 0.4 0.00082 20.0 0.4 5.6 3 2 3 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFM23760.1 - 0.0015 18.8 0.6 0.94 10.0 0.0 3.2 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFM23760.1 - 0.0023 18.1 3.3 0.0023 18.1 3.3 3.3 3 2 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFM23760.1 - 0.0054 17.0 14.7 0.011 16.0 0.4 3.6 3 1 1 4 4 4 2 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KFM23760.1 - 0.0066 16.9 0.4 0.021 15.3 0.1 2.0 1 1 0 2 2 2 1 Alkyl sulfatase dimerisation ATP-sulfurylase PF01747.17 KFM23760.1 - 0.022 14.2 0.2 0.041 13.3 0.2 1.4 1 0 0 1 1 1 0 ATP-sulfurylase Fis1_TPR_C PF14853.6 KFM23760.1 - 0.031 14.3 2.3 0.035 14.2 0.0 2.1 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 KFM23760.1 - 0.049 13.5 0.0 0.049 13.5 0.0 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat NRBF2_MIT PF17169.4 KFM23760.1 - 0.14 12.4 0.1 0.14 12.4 0.1 2.7 3 0 0 3 3 3 0 MIT domain of nuclear receptor-binding factor 2 Peptidase_C97 PF05903.14 KFM23761.1 - 1.1e-39 135.7 0.0 1.3e-39 135.4 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain AAA PF00004.29 KFM23762.1 - 9.3e-41 139.3 0.0 1.9e-40 138.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KFM23762.1 - 9.9e-19 67.1 0.2 2.2e-18 66.0 0.2 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KFM23762.1 - 8.6e-12 44.7 0.5 1.9e-11 43.5 0.5 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KFM23762.1 - 8.5e-07 29.0 0.0 3.4e-06 27.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFM23762.1 - 5.1e-06 27.0 1.5 0.00059 20.3 0.1 2.7 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 KFM23762.1 - 1.9e-05 24.4 0.0 4.8e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KFM23762.1 - 6e-05 23.3 1.0 0.038 14.3 0.0 2.6 1 1 0 2 2 2 2 AAA domain AAA_2 PF07724.14 KFM23762.1 - 8.4e-05 22.8 0.0 0.00043 20.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KFM23762.1 - 0.0065 16.6 0.0 0.02 15.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 KFM23762.1 - 0.016 14.9 0.1 0.25 11.0 0.0 2.3 2 1 0 2 2 2 0 Sigma-54 interaction domain CPT PF07931.12 KFM23762.1 - 0.023 14.5 0.0 0.048 13.5 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein PhoH PF02562.16 KFM23762.1 - 0.028 13.9 0.0 0.077 12.4 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein Prot_ATP_OB_N PF17758.1 KFM23762.1 - 0.035 13.8 0.0 0.73 9.5 0.0 2.4 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain Mg_chelatase PF01078.21 KFM23762.1 - 0.039 13.3 0.0 0.098 12.0 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 KFM23762.1 - 0.039 13.3 0.1 0.13 11.5 0.0 1.9 2 0 0 2 2 2 0 KaiC AAA_18 PF13238.6 KFM23762.1 - 0.053 14.1 0.1 0.49 10.9 0.0 2.5 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KFM23762.1 - 0.059 13.1 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 KFM23762.1 - 0.06 12.5 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_11 PF13086.6 KFM23762.1 - 0.066 13.0 2.6 0.078 12.8 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KFM23762.1 - 0.082 12.4 0.0 0.17 11.4 0.0 1.5 1 1 0 1 1 1 0 P-loop containing dynein motor region DUF2312 PF10073.9 KFM23762.1 - 0.094 12.4 2.6 0.078 12.6 0.6 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) DUF815 PF05673.13 KFM23762.1 - 0.11 11.7 0.0 0.23 10.6 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 KFM23762.1 - 0.14 12.2 0.0 0.39 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain FancD2 PF14631.6 KFM23763.1 - 1.1e-63 215.3 0.0 7.4e-28 96.6 0.0 4.0 4 0 0 4 4 4 4 Fanconi anaemia protein FancD2 nuclease DUF2600 PF10776.9 KFM23763.1 - 0.0009 18.2 0.0 0.82 8.5 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2600) Tox-SHH PF15652.6 KFM23763.1 - 0.11 13.5 0.1 37 5.3 0.0 2.5 2 0 0 2 2 2 0 HNH/Endo VII superfamily toxin with a SHH signature FliT PF05400.13 KFM23763.1 - 0.2 12.5 4.1 31 5.5 0.0 4.3 4 0 0 4 4 4 0 Flagellar protein FliT DnaJ PF00226.31 KFM23764.1 - 5.6e-17 61.6 0.3 7.7e-17 61.2 0.3 1.2 1 0 0 1 1 1 1 DnaJ domain Fer4_13 PF13370.6 KFM23764.1 - 3.1e-10 40.4 0.4 6.2e-10 39.5 0.4 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_10 PF13237.6 KFM23764.1 - 1e-05 25.6 0.3 1.5e-05 25.0 0.3 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_15 PF13459.6 KFM23764.1 - 2.3e-05 25.0 2.5 2.5e-05 24.9 1.1 1.8 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_7 PF12838.7 KFM23764.1 - 5.9e-05 23.6 0.2 9.5e-05 22.9 0.2 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 KFM23764.1 - 0.00035 20.3 3.1 0.00063 19.4 3.1 1.4 1 0 0 1 1 1 1 4Fe-4S binding domain Fer4_9 PF13187.6 KFM23764.1 - 0.00057 20.0 0.1 0.00079 19.5 0.1 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 KFM23764.1 - 0.00076 19.6 0.1 0.0012 18.9 0.1 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KFM23764.1 - 0.00077 19.4 2.3 0.0014 18.6 2.3 1.3 1 0 0 1 1 1 1 4Fe-4S binding domain Fer4_2 PF12797.7 KFM23764.1 - 0.0013 18.7 2.8 0.0023 17.9 2.8 1.4 1 0 0 1 1 1 1 4Fe-4S binding domain Fer4_18 PF13746.6 KFM23764.1 - 0.0015 18.7 0.0 0.0022 18.2 0.0 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KFM23764.1 - 0.0025 18.7 0.1 0.0039 18.1 0.1 1.4 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_17 PF13534.6 KFM23764.1 - 0.0071 16.9 0.1 0.0095 16.5 0.1 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KFM23764.1 - 0.019 15.4 2.3 0.056 13.9 2.6 1.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 KFM23764.1 - 0.058 13.9 1.1 0.093 13.3 1.1 1.2 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4_3 PF12798.7 KFM23764.1 - 0.16 12.9 4.6 0.25 12.4 4.6 1.3 1 0 0 1 1 1 0 4Fe-4S binding domain MFS_1 PF07690.16 KFM23765.1 - 7.9e-23 80.9 46.2 7.9e-23 80.9 46.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DnaJ PF00226.31 KFM23765.1 - 7.3e-16 58.0 0.3 1.2e-15 57.4 0.3 1.3 1 0 0 1 1 1 1 DnaJ domain Fer4_13 PF13370.6 KFM23765.1 - 5.9e-08 33.1 0.1 1.2e-07 32.1 0.1 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 KFM23765.1 - 0.0092 16.7 0.1 0.026 15.3 0.1 1.8 1 0 0 1 1 1 1 4Fe-4S single cluster domain RNase_T PF00929.24 KFM23766.1 - 0.00063 20.3 0.0 0.0014 19.2 0.0 1.6 1 1 0 1 1 1 1 Exonuclease Pyr_redox_2 PF07992.14 KFM23767.1 - 1.4e-50 172.2 0.4 2.1e-50 171.6 0.4 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFM23767.1 - 6.1e-20 71.7 0.0 1.9e-15 56.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thioredoxin PF00085.20 KFM23767.1 - 5e-16 58.6 0.0 8.5e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Pyr_redox PF00070.27 KFM23767.1 - 1.1e-15 58.0 0.5 2.6e-14 53.5 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFM23767.1 - 1.2e-05 25.5 3.3 0.0027 17.9 0.0 3.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KFM23767.1 - 3.6e-05 22.7 0.1 0.013 14.3 0.1 3.0 2 1 1 3 3 3 1 HI0933-like protein Glutaredoxin PF00462.24 KFM23767.1 - 3.6e-05 23.9 0.0 0.00015 21.9 0.0 2.0 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin_2 PF13098.6 KFM23767.1 - 5.9e-05 23.5 0.1 0.00039 20.8 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain FAD_oxidored PF12831.7 KFM23767.1 - 0.00025 20.5 6.5 0.0012 18.3 0.1 2.8 3 1 0 3 3 3 1 FAD dependent oxidoreductase Thioredoxin_4 PF13462.6 KFM23767.1 - 0.00069 19.8 0.1 0.0096 16.1 0.1 2.3 1 1 0 1 1 1 1 Thioredoxin TraF PF13728.6 KFM23767.1 - 0.0013 18.6 0.0 0.0024 17.7 0.0 1.4 1 0 0 1 1 1 1 F plasmid transfer operon protein FAD_binding_2 PF00890.24 KFM23767.1 - 0.0017 17.6 0.1 0.0017 17.6 0.1 2.9 3 2 0 3 3 3 1 FAD binding domain OST3_OST6 PF04756.13 KFM23767.1 - 0.0019 17.6 0.0 0.0028 17.1 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family K_oxygenase PF13434.6 KFM23767.1 - 0.0026 16.9 0.0 0.84 8.7 0.0 2.7 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KFM23767.1 - 0.0031 16.8 0.1 0.035 13.3 0.0 2.3 2 0 0 2 2 2 1 Thi4 family Thioredoxin_3 PF13192.6 KFM23767.1 - 0.0045 17.0 0.0 0.0098 15.9 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin domain AhpC-TSA PF00578.21 KFM23767.1 - 0.0052 16.7 0.0 0.0087 16.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family GIDA PF01134.22 KFM23767.1 - 0.0055 15.8 7.0 0.029 13.5 0.1 3.3 4 0 0 4 4 4 1 Glucose inhibited division protein A Thioredoxin_5 PF13743.6 KFM23767.1 - 0.011 15.5 0.1 1.4 8.5 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin DUF836 PF05768.14 KFM23767.1 - 0.015 15.7 0.1 0.055 13.9 0.0 1.9 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) Thioredoxin_8 PF13905.6 KFM23767.1 - 0.018 15.3 0.0 0.034 14.5 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like HyaE PF07449.11 KFM23767.1 - 0.023 14.7 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Ntox10 PF15520.6 KFM23767.1 - 0.031 14.1 0.2 0.088 12.7 0.0 1.8 2 0 0 2 2 2 0 Novel toxin 10 NAD_binding_7 PF13241.6 KFM23767.1 - 0.1 13.1 0.2 0.62 10.5 0.1 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding Iwr1 PF08574.10 KFM23768.1 - 2.1e-10 41.5 2.7 5.4e-10 40.1 2.7 1.7 1 0 0 1 1 1 1 Transcription factor Iwr1 Kri1 PF05178.12 KFM23769.1 - 2e-18 66.8 3.6 2e-18 66.8 3.6 3.4 2 1 0 2 2 2 1 KRI1-like family Kri1_C PF12936.7 KFM23769.1 - 1.2e-13 51.0 0.0 1.2e-13 51.0 0.0 3.1 3 0 0 3 3 3 1 KRI1-like family C-terminal FliT PF05400.13 KFM23769.1 - 0.079 13.8 15.5 0.14 13.0 0.5 3.9 4 0 0 4 4 4 0 Flagellar protein FliT DUF573 PF04504.14 KFM23769.1 - 0.11 13.2 0.8 0.44 11.2 0.8 2.0 1 0 0 1 1 1 0 Protein of unknown function, DUF573 HrpJ PF07201.11 KFM23769.1 - 0.57 10.5 11.5 0.47 10.8 7.1 2.5 2 0 0 2 2 2 0 HrpJ-like domain SATase_N PF06426.14 KFM23770.1 - 5.4e-32 110.3 0.7 7.9e-32 109.8 0.7 1.3 1 0 0 1 1 1 1 Serine acetyltransferase, N-terminal Hexapep PF00132.24 KFM23770.1 - 1.2e-11 43.8 12.4 1.3e-06 27.9 3.1 2.5 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KFM23770.1 - 0.0048 16.6 16.0 0.013 15.2 4.3 2.7 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase SATase_N PF06426.14 KFM23771.1 - 2.2e-34 118.0 0.1 3.6e-34 117.3 0.1 1.4 1 0 0 1 1 1 1 Serine acetyltransferase, N-terminal Hexapep PF00132.24 KFM23771.1 - 2.6e-10 39.6 10.3 7.6e-09 35.0 3.1 2.3 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KFM23771.1 - 3e-05 23.7 5.8 3e-05 23.7 5.8 2.3 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase SIS PF01380.22 KFM23772.1 - 2.4e-52 176.3 0.6 2.1e-32 111.7 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 KFM23772.1 - 4.7e-13 49.5 0.1 1.3e-12 48.1 0.1 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KFM23772.1 - 1.1e-06 28.6 0.0 2.3e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain SIS_2 PF13580.6 KFM23772.1 - 0.00063 19.8 0.0 0.019 15.0 0.0 2.6 1 1 1 2 2 2 1 SIS domain GATase_4 PF13230.6 KFM23772.1 - 0.01 14.8 0.3 0.017 14.0 0.3 1.2 1 0 0 1 1 1 0 Glutamine amidotransferases class-II DUF2529 PF10740.9 KFM23772.1 - 0.053 13.2 0.1 0.98 9.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2529) CTNNBL PF08216.11 KFM23773.1 - 1.4e-26 92.7 0.0 3.9e-26 91.2 0.0 1.8 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear DUF913 PF06025.12 KFM23773.1 - 0.55 9.2 3.1 2.4 7.1 0.0 3.2 4 1 0 4 4 4 0 Domain of Unknown Function (DUF913) Arm PF00514.23 KFM23773.1 - 0.71 10.0 4.1 1.1 9.4 0.0 3.3 4 1 0 4 4 4 0 Armadillo/beta-catenin-like repeat Pkinase PF00069.25 KFM23774.1 - 1.2e-11 44.5 0.0 1.7e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH3_4 PF06347.13 KFM23774.1 - 0.083 12.7 0.5 0.38 10.6 0.2 2.1 2 0 0 2 2 2 0 Bacterial SH3 domain Pkinase_Tyr PF07714.17 KFM23774.1 - 0.22 10.8 0.1 2.8 7.1 0.0 2.0 2 0 0 2 2 2 0 Protein tyrosine kinase Pkinase PF00069.25 KFM23775.1 - 5.7e-64 216.0 0.0 6.6e-64 215.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM23775.1 - 3.9e-24 85.3 0.0 6.5e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFM23775.1 - 0.0015 17.9 0.1 0.0041 16.5 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFM23775.1 - 0.0043 17.0 2.8 0.057 13.3 0.4 2.8 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KFM23775.1 - 0.0086 15.4 0.1 0.33 10.2 0.0 2.1 1 1 0 2 2 2 1 Kinase-like FTA2 PF13095.6 KFM23775.1 - 0.15 11.7 0.0 0.41 10.2 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DnaJ PF00226.31 KFM23776.1 - 0.079 13.1 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 DnaJ domain Glutaredoxin PF00462.24 KFM23777.1 - 9.7e-20 70.5 0.5 3.1e-19 68.9 0.3 1.8 2 0 0 2 2 2 1 Glutaredoxin DUF836 PF05768.14 KFM23777.1 - 0.0011 19.3 0.1 0.0016 18.8 0.1 1.4 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 KFM23777.1 - 0.0021 18.5 0.1 0.0023 18.4 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain GST_N_3 PF13417.6 KFM23777.1 - 0.0057 17.0 0.0 0.01 16.2 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_9 PF14595.6 KFM23777.1 - 0.012 15.4 0.0 0.013 15.3 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Thioredoxin PF00085.20 KFM23777.1 - 0.027 14.5 0.1 0.031 14.2 0.1 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_3 PF13192.6 KFM23777.1 - 0.031 14.3 0.1 0.059 13.4 0.1 1.4 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_4 PF13462.6 KFM23777.1 - 0.039 14.1 0.8 0.31 11.2 0.6 2.0 1 1 1 2 2 2 0 Thioredoxin Redoxin PF08534.10 KFM23777.1 - 0.048 13.4 0.6 1.3 8.8 0.4 2.0 1 1 1 2 2 2 0 Redoxin DUF775 PF05603.12 KFM23778.1 - 1.3e-13 51.0 0.0 2.3e-11 43.6 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF775) SBF PF01758.16 KFM23779.1 - 3.9e-32 111.5 14.2 3.9e-32 111.5 14.2 1.7 2 0 0 2 2 2 1 Sodium Bile acid symporter family SBF_like PF13593.6 KFM23779.1 - 2.4e-13 50.1 19.8 3.4e-13 49.6 19.8 1.2 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) BNR_2 PF13088.6 KFM23781.1 - 1.4e-32 113.1 0.1 1e-30 107.0 0.2 2.8 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.20 KFM23781.1 - 1.7e-07 30.1 8.7 0.2 11.7 0.2 5.4 5 0 0 5 5 5 3 BNR/Asp-box repeat Mo-co_dimer PF03404.16 KFM23781.1 - 0.027 14.5 0.1 13 5.8 0.0 3.4 4 0 0 4 4 4 0 Mo-co oxidoreductase dimerisation domain DUF716 PF04819.12 KFM23782.1 - 2.1e-18 66.3 7.1 3.6e-18 65.6 7.1 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF716) Peptidase_C1 PF00112.23 KFM23783.1 - 1.2e-48 166.1 1.7 1.6e-48 165.7 1.7 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KFM23783.1 - 0.016 14.0 0.2 0.025 13.3 0.2 1.2 1 0 0 1 1 1 0 Peptidase C1-like family DnaJ PF00226.31 KFM23784.1 - 2.3e-15 56.5 0.0 3.9e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain TPR_2 PF07719.17 KFM23785.1 - 0.00033 20.5 0.0 0.29 11.3 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFM23785.1 - 0.0011 19.5 0.0 0.56 11.0 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFM23785.1 - 0.011 15.6 0.1 0.09 12.6 0.1 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFM23785.1 - 0.07 13.4 0.1 0.4 11.0 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat MORN PF02493.20 KFM23786.1 - 1.5e-05 24.6 7.9 0.0012 18.6 0.7 3.6 4 0 0 4 4 4 2 MORN repeat Arf PF00025.21 KFM23787.1 - 3.9e-45 153.4 0.0 4.2e-45 153.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KFM23787.1 - 7e-17 61.5 0.0 7.9e-17 61.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM23787.1 - 8e-15 55.1 0.0 1.3e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KFM23787.1 - 1.6e-10 40.7 0.0 2.7e-10 40.0 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KFM23787.1 - 9.3e-09 35.0 0.0 9.4e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFM23787.1 - 2e-08 34.3 0.0 3.1e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 KFM23787.1 - 1.6e-05 24.3 0.4 3e-05 23.4 0.1 1.6 1 1 1 2 2 2 1 G-protein alpha subunit FeoB_N PF02421.18 KFM23787.1 - 0.016 14.8 0.0 0.031 13.8 0.0 1.6 1 0 0 1 1 1 0 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KFM23787.1 - 0.11 12.3 0.1 14 5.6 0.1 2.1 2 0 0 2 2 2 0 RsgA GTPase Dynamin_N PF00350.23 KFM23787.1 - 0.15 12.1 0.1 0.93 9.5 0.2 2.0 1 1 1 2 2 2 0 Dynamin family Glycos_transf_1 PF00534.20 KFM23788.1 - 1.1e-29 103.1 0.0 1.6e-28 99.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KFM23788.1 - 1.9e-28 99.5 0.5 2e-27 96.2 0.6 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KFM23788.1 - 1.1e-22 80.9 0.1 2.9e-22 79.5 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KFM23788.1 - 2.3e-12 47.6 0.1 2.3e-12 47.6 0.1 2.5 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KFM23788.1 - 1.6e-11 44.5 0.0 1.4e-10 41.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 KFM23788.1 - 5.3e-07 29.7 0.0 1.3e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like Myb_DNA-binding PF00249.31 KFM23789.1 - 1.1e-31 108.7 3.7 1.2e-14 54.2 0.1 4.8 5 0 0 5 5 5 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFM23789.1 - 2e-19 69.5 0.0 6.3e-09 36.0 0.0 4.8 3 2 2 5 5 5 5 Myb-like DNA-binding domain Rap1_C PF11626.8 KFM23789.1 - 0.21 11.7 0.5 0.6 10.2 0.5 1.8 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF4096 PF13340.6 KFM23789.1 - 0.26 11.5 2.5 13 6.1 0.2 4.0 4 0 0 4 4 4 0 Putative transposase of IS4/5 family (DUF4096) DUF563 PF04577.14 KFM23790.1 - 3.6e-14 53.4 0.8 8.3e-14 52.2 0.5 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF563) TPR_1 PF00515.28 KFM23791.1 - 4.4e-06 26.3 1.9 0.0014 18.4 0.2 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFM23791.1 - 7.8e-06 25.6 6.9 0.0085 16.1 0.5 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat SET PF00856.28 KFM23791.1 - 0.0052 17.2 0.0 0.0089 16.4 0.0 1.4 1 0 0 1 1 1 1 SET domain TPR_11 PF13414.6 KFM23791.1 - 0.092 12.4 0.7 22 4.8 0.1 3.2 3 0 0 3 3 3 0 TPR repeat TPR_17 PF13431.6 KFM23791.1 - 0.35 11.3 1.8 16 6.2 0.5 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFM23791.1 - 5.5 7.4 10.9 17 5.8 3.2 4.2 3 1 0 3 3 3 0 Tetratricopeptide repeat DHQ_synthase PF01761.20 KFM23792.1 - 3.7e-107 357.4 0.0 4.5e-107 357.1 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 KFM23792.1 - 2.2e-12 47.3 0.7 2.3e-11 43.9 0.7 2.0 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 KFM23792.1 - 6.7e-07 28.4 2.3 1.2e-06 27.6 2.3 1.5 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase PTCB-BRCT PF12738.7 KFM23794.1 - 2.4e-20 72.2 2.4 2.3e-11 43.4 0.0 2.8 3 0 0 3 3 3 2 twin BRCT domain BRCT PF00533.26 KFM23794.1 - 9.1e-11 42.0 0.0 0.0005 20.4 0.0 2.9 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KFM23794.1 - 7.3e-10 39.1 0.0 0.028 14.8 0.0 3.5 4 0 0 4 4 4 3 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KFM23794.1 - 2e-06 28.0 0.1 0.15 12.4 0.0 3.0 3 0 0 3 3 3 2 DNA ligase 3 BRCT domain CENP-F_leu_zip PF10473.9 KFM23795.1 - 0.0036 17.3 1.9 0.0077 16.3 1.9 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HAP1_N PF04849.13 KFM23795.1 - 0.011 15.0 0.1 0.017 14.3 0.1 1.3 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Laminin_II PF06009.12 KFM23795.1 - 0.04 13.9 3.0 0.032 14.2 1.2 1.6 2 0 0 2 2 2 0 Laminin Domain II Snapin_Pallidin PF14712.6 KFM23795.1 - 0.053 14.0 1.1 0.42 11.1 0.5 2.2 1 1 1 2 2 2 0 Snapin/Pallidin DivIC PF04977.15 KFM23795.1 - 0.13 12.1 1.5 0.29 11.0 0.9 1.8 1 1 1 2 2 2 0 Septum formation initiator APG6_N PF17675.1 KFM23795.1 - 0.14 12.7 5.3 0.064 13.8 2.1 1.9 2 0 0 2 2 2 0 Apg6 coiled-coil region FlxA PF14282.6 KFM23795.1 - 0.78 9.8 7.1 0.12 12.3 3.0 1.8 2 0 0 2 2 2 0 FlxA-like protein LPP PF04728.13 KFM23795.1 - 2.5 8.6 5.6 1.1 9.7 0.9 2.4 2 0 0 2 2 2 0 Lipoprotein leucine-zipper ADIP PF11559.8 KFM23795.1 - 8.8 6.4 8.2 1.1 9.4 2.6 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding 2Fe-2S_thioredx PF01257.19 KFM23796.1 - 2.8e-05 24.0 0.4 0.00018 21.4 0.4 1.8 1 1 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin NIR_SIR_ferr PF03460.17 KFM23796.1 - 0.024 14.5 0.0 0.026 14.3 0.0 1.3 1 1 0 1 1 1 0 Nitrite/Sulfite reductase ferredoxin-like half domain RelA_SpoT PF04607.17 KFM23798.1 - 3.9e-21 75.5 0.0 5.2e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins Mito_carr PF00153.27 KFM23799.1 - 1.5e-16 60.1 6.6 1.2e-05 25.1 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_S19 PF00203.21 KFM23800.1 - 1.2e-33 114.8 0.1 1.6e-33 114.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 UPF0236 PF06782.11 KFM23800.1 - 0.0026 16.5 0.1 0.0032 16.2 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0236) ALC PF17527.2 KFM23800.1 - 0.093 12.4 0.2 0.17 11.5 0.2 1.4 1 1 1 2 2 2 0 Phage ALC protein UQ_con PF00179.26 KFM23801.1 - 4.4e-34 117.1 0.0 4.9e-34 117.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFM23801.1 - 0.14 12.4 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 RWD domain WD40 PF00400.32 KFM23803.1 - 2.9e-09 37.4 5.1 0.053 14.4 0.1 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat SRA1 PF07304.11 KFM23803.1 - 0.00013 21.8 0.0 0.00013 21.8 0.0 2.3 2 1 0 2 2 2 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.7 KFM23803.1 - 0.062 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 Keratin_2_tail PF16210.5 KFM23803.1 - 0.84 9.9 10.3 3.1 8.1 10.3 2.0 1 0 0 1 1 1 0 Keratin type II cytoskeletal 1 tail Glycos_transf_2 PF00535.26 KFM23804.1 - 4.3e-33 114.5 0.0 5.2e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KFM23804.1 - 5.7e-15 55.8 0.0 1.2e-14 54.8 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KFM23804.1 - 2.4e-07 30.4 0.0 3.7e-07 29.8 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 KFM23804.1 - 1.4e-05 24.7 0.0 1.9e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 KFM23804.1 - 0.016 15.7 0.0 0.036 14.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 ETC_C1_NDUFA4 PF04800.12 KFM23805.1 - 1.2e-23 83.1 0.0 5e-23 81.2 0.0 1.8 1 1 0 1 1 1 1 ETC complex I subunit conserved region ATP-sulfurylase PF01747.17 KFM23806.1 - 1e-68 231.0 0.0 1.4e-68 230.6 0.0 1.1 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 KFM23806.1 - 3e-37 127.7 0.0 4.6e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 PUA-like domain Glycoprotein PF03409.15 KFM23807.1 - 0.16 10.8 4.7 0.33 9.7 2.5 1.9 2 0 0 2 2 2 0 Transmembrane glycoprotein DUF4211 PF13926.6 KFM23809.1 - 0.00021 21.4 0.0 0.00038 20.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) zf-Tim10_DDP PF02953.15 KFM23810.1 - 4.5e-17 61.4 6.1 4.5e-17 61.4 6.1 1.4 2 0 0 2 2 2 1 Tim10/DDP family zinc finger Latarcin PF10279.9 KFM23810.1 - 0.058 13.8 0.1 0.08 13.3 0.1 1.2 1 0 0 1 1 1 0 Latarcin precursor AAA_lid_2 PF17863.1 KFM23811.1 - 6.7e-14 51.5 0.1 1.7e-13 50.2 0.1 1.7 1 0 0 1 1 1 1 AAA lid domain AAA_16 PF13191.6 KFM23811.1 - 0.0019 18.6 2.0 0.021 15.2 0.0 3.2 4 0 0 4 4 4 1 AAA ATPase domain DUF815 PF05673.13 KFM23811.1 - 0.011 14.9 0.0 0.053 12.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 KFM23811.1 - 0.07 12.5 0.0 0.2 11.0 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 KFM23811.1 - 0.077 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pkinase_Tyr PF07714.17 KFM23812.1 - 1.3e-36 126.3 0.0 3.5e-36 124.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM23812.1 - 4.1e-31 108.3 0.0 6.3e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KFM23812.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L30_N PF08079.12 KFM23813.1 - 5.1e-29 100.3 13.9 5.1e-29 100.3 13.9 1.7 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 KFM23813.1 - 5.4e-18 64.6 2.5 5.4e-18 64.6 2.5 1.8 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e DUF1990 PF09348.10 KFM23813.1 - 0.053 13.6 0.0 0.073 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1990) WD40 PF00400.32 KFM23814.1 - 2.1e-24 85.3 0.7 5.2e-06 27.1 0.0 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat Prp19 PF08606.11 KFM23814.1 - 1.6e-22 79.2 0.2 3.1e-22 78.3 0.2 1.4 1 0 0 1 1 1 1 Prp19/Pso4-like ANAPC4_WD40 PF12894.7 KFM23814.1 - 2.7e-12 46.8 0.1 0.027 14.8 0.0 5.2 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain zf-Nse PF11789.8 KFM23814.1 - 0.071 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PDCD7 PF16021.5 KFM23814.1 - 0.099 11.7 0.1 0.15 11.1 0.1 1.1 1 0 0 1 1 1 0 Programmed cell death protein 7 GATA PF00320.27 KFM23815.1 - 1.5e-15 56.5 4.7 2.2e-15 56.0 4.7 1.3 1 0 0 1 1 1 1 GATA zinc finger Zn-ribbon_8 PF09723.10 KFM23815.1 - 0.14 12.3 0.7 0.37 10.9 0.7 1.7 1 1 0 1 1 1 0 Zinc ribbon domain OrfB_Zn_ribbon PF07282.11 KFM23815.1 - 0.2 11.6 1.5 0.24 11.4 0.6 1.6 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Rubredoxin_2 PF18073.1 KFM23815.1 - 0.23 11.2 4.7 6.4 6.6 0.7 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain DZR PF12773.7 KFM23815.1 - 0.28 11.3 4.2 1 9.4 4.2 1.9 1 1 0 1 1 1 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.7 KFM23815.1 - 0.42 10.6 4.0 0.94 9.5 3.9 1.7 1 1 0 1 1 1 0 Transposase zinc-ribbon domain Vps36-NZF-N PF16988.5 KFM23815.1 - 1.1 8.7 4.7 2.6 7.5 0.3 2.5 2 1 1 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain STI1 PF17830.1 KFM23816.1 - 2.6e-11 43.3 8.3 2.6e-11 43.3 8.3 4.1 3 1 2 5 5 5 2 STI1 domain RPN13_C PF16550.5 KFM23816.1 - 0.0043 17.2 3.5 0.017 15.3 0.6 2.6 1 1 1 2 2 2 1 UCH-binding domain DUF2780 PF11075.8 KFM23816.1 - 1.2 9.3 9.6 0.99 9.5 5.4 2.7 2 1 0 2 2 2 0 Protein of unknown function VcgC/VcgE (DUF2780) Rhomboid PF01694.22 KFM23817.1 - 1.5e-22 80.2 27.8 1.6e-18 67.1 12.8 3.2 3 1 1 4 4 4 2 Rhomboid family Ribosomal_L18 PF17135.4 KFM23818.1 - 5.4e-92 306.3 0.7 5.9e-92 306.2 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 KFM23818.1 - 0.0033 18.1 0.4 0.012 16.3 0.4 2.0 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A EST1 PF10374.9 KFM23819.1 - 4.8e-09 37.0 0.0 7.5e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Telomerase activating protein Est1 EST1_DNA_bind PF10373.9 KFM23819.1 - 3.4e-05 23.4 0.1 5.3e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain Metallophos PF00149.28 KFM23820.1 - 2.4e-39 135.9 0.1 3e-39 135.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_MLP1_2 PF07926.12 KFM23821.1 - 0.0053 16.8 18.3 0.0053 16.8 18.3 6.9 3 2 2 6 6 6 2 TPR/MLP1/MLP2-like protein GATA PF00320.27 KFM23821.1 - 0.15 11.7 0.4 0.23 11.1 0.4 1.3 1 0 0 1 1 1 0 GATA zinc finger CENP-F_leu_zip PF10473.9 KFM23821.1 - 3.1 7.8 57.7 0.096 12.7 19.1 5.5 2 1 4 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EF-hand_1 PF00036.32 KFM23822.1 - 1.2e-30 102.7 17.0 3.7e-08 32.4 0.1 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KFM23822.1 - 3.9e-28 97.7 11.1 1.1e-15 57.9 0.6 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFM23822.1 - 1.5e-24 83.8 11.7 1.8e-08 33.6 0.1 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KFM23822.1 - 1.1e-22 79.6 10.9 3.4e-11 42.8 2.2 3.7 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 KFM23822.1 - 1.2e-14 54.4 0.5 5.4e-06 26.6 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KFM23822.1 - 6.4e-13 47.6 18.1 0.00016 21.0 0.1 4.9 4 1 0 4 4 4 4 EF hand WD40 PF00400.32 KFM23822.1 - 2.4e-10 40.8 10.9 0.0002 22.1 0.0 6.0 7 0 0 7 7 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM23822.1 - 3.3e-10 40.1 0.1 0.0098 16.2 0.0 4.4 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_4 PF12763.7 KFM23822.1 - 0.00061 19.7 5.6 0.92 9.5 0.6 3.4 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SurA_N_2 PF13623.6 KFM23822.1 - 0.014 15.2 0.5 3.6 7.4 0.3 2.6 1 1 1 2 2 2 0 SurA N-terminal domain Formyl_trans_C PF02911.18 KFM23822.1 - 0.024 14.9 0.0 2.2 8.6 0.0 2.7 2 0 0 2 2 2 0 Formyl transferase, C-terminal domain Herpes_UL56 PF04534.12 KFM23822.1 - 0.026 14.0 0.1 0.054 13.0 0.1 1.5 1 0 0 1 1 1 0 Herpesvirus UL56 protein EF-hand_14 PF17959.1 KFM23822.1 - 0.071 13.5 0.8 1.3 9.4 0.2 2.3 2 0 0 2 2 2 0 EF-hand domain SurA_N_3 PF13624.6 KFM23822.1 - 0.072 12.9 1.1 4.7 7.0 0.4 2.2 1 1 1 2 2 2 0 SurA N-terminal domain SUB1_ProdP9 PF18213.1 KFM23822.1 - 0.11 12.4 0.2 0.2 11.5 0.2 1.4 1 0 0 1 1 1 0 SUB1 protease Prodomain ProdP9 SPARC_Ca_bdg PF10591.9 KFM23822.1 - 0.13 12.6 0.0 26 5.2 0.2 2.2 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region cwf21 PF08312.12 KFM23825.1 - 1.7e-11 44.1 2.3 1.7e-11 44.1 2.3 2.2 2 0 0 2 2 2 1 cwf21 domain Hamartin PF04388.12 KFM23825.1 - 0.48 9.0 13.4 0.55 8.8 13.4 1.0 1 0 0 1 1 1 0 Hamartin protein TMEM214 PF10151.9 KFM23825.1 - 5.2 5.4 13.6 6.7 5.0 13.6 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator MAT1 PF06391.13 KFM23826.1 - 3.8e-22 79.1 1.5 4.7e-22 78.8 1.5 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 VirK PF06903.12 KFM23826.1 - 0.23 11.6 0.0 28 4.9 0.0 2.4 2 0 0 2 2 2 0 VirK protein DSPc PF00782.20 KFM23827.1 - 1.9e-07 30.9 0.0 2.5e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFM23827.1 - 0.03 13.9 0.0 0.037 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DnaJ PF00226.31 KFM23828.1 - 1.9e-15 56.7 0.5 5e-15 55.4 0.5 1.8 1 1 0 1 1 1 1 DnaJ domain DUF2428 PF10350.9 KFM23829.1 - 8.8e-40 136.7 0.0 1.5e-39 135.9 0.0 1.4 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT_2 PF13646.6 KFM23829.1 - 3.1e-05 24.3 4.6 3.1e-05 24.3 4.6 6.3 7 0 0 7 7 7 1 HEAT repeats Arm PF00514.23 KFM23829.1 - 0.07 13.2 5.7 4.4 7.5 0.5 4.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KFM23829.1 - 0.15 12.4 22.8 0.089 13.1 0.8 6.5 6 0 0 6 6 6 0 HEAT repeat Glyco_transf_7N PF13733.6 KFM23830.1 - 3.7e-23 81.7 0.0 5.9e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 KFM23830.1 - 2e-13 49.8 0.0 4.1e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase TMP-TENI PF02581.17 KFM23831.1 - 4.7e-60 202.0 2.4 7.9e-60 201.3 2.4 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase Phos_pyr_kin PF08543.12 KFM23831.1 - 1.6e-36 125.9 0.1 1e-32 113.5 0.0 2.8 2 1 1 3 3 3 2 Phosphomethylpyrimidine kinase HAD PF12710.7 KFM23831.1 - 4.7e-07 30.4 4.0 9.8e-06 26.1 1.3 3.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase PfkB PF00294.24 KFM23831.1 - 0.00018 21.0 0.1 0.00046 19.6 0.1 1.7 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Put_Phosphatase PF06888.12 KFM23831.1 - 0.0021 17.5 0.0 1.4 8.2 0.0 2.3 2 0 0 2 2 2 2 Putative Phosphatase ThiG PF05690.14 KFM23831.1 - 0.038 13.3 5.4 0.14 11.4 5.4 1.9 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG Peripla_BP_4 PF13407.6 KFM23831.1 - 0.78 9.3 7.8 3.5 7.1 0.1 3.0 2 2 0 2 2 2 0 Periplasmic binding protein domain Trm112p PF03966.16 KFM23832.1 - 4.7e-15 55.9 0.0 5.6e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 Trm112p-like protein TENA_THI-4 PF03070.16 KFM23833.1 - 6.3e-24 85.0 0.1 7.9e-24 84.6 0.1 1.0 1 0 0 1 1 1 1 TENA/THI-4/PQQC family HK PF02110.15 KFM23834.1 - 6.3e-76 255.0 2.4 7.3e-76 254.8 2.4 1.0 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Carb_kinase PF01256.17 KFM23834.1 - 0.02 14.4 0.7 0.036 13.6 0.7 1.4 1 0 0 1 1 1 0 Carbohydrate kinase PAC4 PF16093.5 KFM23834.1 - 0.12 12.6 0.2 0.3 11.3 0.2 1.9 1 1 0 1 1 1 0 Proteasome assembly chaperone 4 TENA_THI-4 PF03070.16 KFM23836.1 - 0.0002 21.3 0.1 0.00025 20.9 0.1 1.1 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Ndc80_HEC PF03801.13 KFM23837.1 - 1.9e-44 151.0 0.0 2.8e-44 150.4 0.0 1.3 1 0 0 1 1 1 1 HEC/Ndc80p family DUF5595 PF18077.1 KFM23837.1 - 0.0039 17.2 5.1 0.076 13.1 0.1 3.8 3 0 0 3 3 3 1 Domain of unknown function (DUF5595) DUF5082 PF16888.5 KFM23837.1 - 0.0071 16.6 1.2 0.31 11.3 0.5 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF5082) GAS PF13851.6 KFM23837.1 - 0.018 14.4 0.3 0.018 14.4 0.3 3.7 4 0 0 4 4 4 0 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 KFM23837.1 - 0.14 12.7 31.2 1.4 9.5 8.6 4.1 2 1 1 3 3 3 0 Apg6 coiled-coil region UPF0242 PF06785.11 KFM23837.1 - 0.36 10.9 3.8 2 8.5 0.6 2.7 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 KFM23837.1 - 1.4 7.7 17.3 0.89 8.4 6.1 3.3 3 1 0 3 3 3 0 Spc7 kinetochore protein Filament PF00038.21 KFM23837.1 - 2.6 7.5 17.8 2.3 7.7 2.5 3.8 2 2 2 4 4 4 0 Intermediate filament protein SlyX PF04102.12 KFM23837.1 - 6.8 7.4 13.8 54 4.5 1.0 4.9 2 2 3 5 5 5 0 SlyX TolA_bind_tri PF16331.5 KFM23837.1 - 9.6 6.4 7.9 6.5 6.9 1.9 3.4 3 1 1 4 4 4 0 TolA binding protein trimerisation Leu_zip PF15294.6 KFM23837.1 - 10 5.6 10.5 2.1 7.8 3.0 3.2 3 1 0 3 3 3 0 Leucine zipper p450 PF00067.22 KFM23838.1 - 7e-57 193.2 0.0 7.6e-34 117.2 0.0 3.0 2 1 1 3 3 3 3 Cytochrome P450 DUF3458_C PF17432.2 KFM23838.1 - 0.72 9.2 3.8 0.99 8.7 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3458_C) ARM repeats PGK PF00162.19 KFM23839.1 - 3.4e-160 533.1 0.4 4.3e-160 532.8 0.4 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Rubella_Capsid PF05750.11 KFM23839.1 - 0.16 11.6 0.0 0.23 11.0 0.0 1.1 1 0 0 1 1 1 0 Rubella capsid protein FF PF01846.19 KFM23843.1 - 1.6e-43 146.6 12.0 2.4e-11 43.6 0.0 5.4 5 0 0 5 5 5 4 FF domain K_oxygenase PF13434.6 KFM23843.1 - 7.9e-10 38.4 0.0 3.5e-06 26.4 0.0 2.6 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) WW PF00397.26 KFM23843.1 - 3.2e-08 33.5 3.0 7.9e-08 32.2 3.0 1.8 1 0 0 1 1 1 1 WW domain Pyr_redox_2 PF07992.14 KFM23843.1 - 2.5e-06 26.9 0.0 8.7e-06 25.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase RhoGAP-FF1 PF16512.5 KFM23843.1 - 0.0013 19.3 5.2 0.67 10.7 0.0 2.6 2 0 0 2 2 2 2 p190-A and -B Rho GAPs FF domain DAO PF01266.24 KFM23843.1 - 0.0019 17.9 0.4 0.0019 17.9 0.4 3.7 3 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KFM23843.1 - 0.031 14.8 0.1 0.12 12.9 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase LNS2 PF08235.13 KFM23844.1 - 1.6e-81 273.1 0.0 2.1e-81 272.7 0.0 1.1 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 KFM23844.1 - 2.9e-15 56.1 0.0 5.9e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 KFM23844.1 - 1.4e-06 28.4 0.0 2.3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Lipin/Ned1/Smp2 multi-domain protein middle domain RWP-RK PF02042.15 KFM23845.1 - 8.8e-21 73.6 0.0 1.6e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain HTH_AraC PF00165.23 KFM23845.1 - 0.044 13.9 0.0 13 6.1 0.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family ABC_membrane PF00664.23 KFM23846.1 - 1.8e-72 244.3 16.0 8.1e-45 153.6 3.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFM23846.1 - 2.9e-49 167.1 0.0 5.6e-30 104.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KFM23846.1 - 4.4e-08 32.8 0.0 0.0096 15.4 0.0 3.5 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KFM23846.1 - 1.6e-07 31.9 1.9 0.0013 19.2 0.2 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KFM23846.1 - 1.6e-06 27.7 0.1 0.059 13.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KFM23846.1 - 5.3e-06 26.5 0.2 0.075 12.8 0.0 3.6 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KFM23846.1 - 1.9e-05 24.4 1.1 0.041 13.5 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 KFM23846.1 - 5.4e-05 23.5 1.6 0.11 12.8 0.0 3.3 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KFM23846.1 - 0.00013 22.0 0.1 0.37 10.9 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFM23846.1 - 0.00024 21.1 0.0 0.03 14.3 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 KFM23846.1 - 0.0025 18.3 0.1 2.5 8.6 0.0 2.2 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 KFM23846.1 - 0.0026 16.9 0.0 0.72 8.9 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF87 PF01935.17 KFM23846.1 - 0.0033 17.5 0.2 3 7.9 0.0 2.3 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_33 PF13671.6 KFM23846.1 - 0.008 16.3 0.1 0.12 12.6 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.6 KFM23846.1 - 0.0089 15.8 2.3 0.16 11.7 0.2 2.9 3 0 0 3 3 3 1 AAA domain cobW PF02492.19 KFM23846.1 - 0.038 13.6 0.5 0.31 10.6 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 KFM23846.1 - 0.048 14.1 0.0 7.1 7.1 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KFM23846.1 - 0.069 12.4 0.1 2.9 7.1 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin NB-ARC PF00931.22 KFM23846.1 - 0.075 12.2 0.2 6.1 6.0 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.12 KFM23846.1 - 0.094 12.6 0.6 7.5 6.4 0.0 2.7 2 0 0 2 2 2 0 NACHT domain Dynamin_N PF00350.23 KFM23846.1 - 0.095 12.8 0.5 0.17 11.9 0.1 1.6 2 0 0 2 2 1 0 Dynamin family RNA_helicase PF00910.22 KFM23846.1 - 0.099 13.0 0.0 24 5.4 0.0 2.6 2 0 0 2 2 2 0 RNA helicase ATP_bind_1 PF03029.17 KFM23846.1 - 0.13 12.1 0.1 5.3 6.7 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ATP-synt_ab PF00006.25 KFM23846.1 - 0.13 11.9 0.0 3.7 7.1 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 KFM23846.1 - 0.14 11.7 0.1 2.5 7.6 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region CLP1_P PF16575.5 KFM23846.1 - 0.16 11.8 0.5 0.31 10.8 0.1 1.7 2 0 0 2 2 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop IstB_IS21 PF01695.17 KFM23846.1 - 0.17 11.6 0.6 2.7 7.7 0.0 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein Adeno_IVa2 PF02456.15 KFM23846.1 - 0.24 10.1 0.2 2.9 6.6 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein ATPase_2 PF01637.18 KFM23846.1 - 0.25 11.2 0.0 12 5.8 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Spc7 PF08317.11 KFM23847.1 - 0.019 13.9 2.3 0.081 11.8 0.4 2.2 2 1 0 2 2 2 0 Spc7 kinetochore protein vATP-synt_E PF01991.18 KFM23847.1 - 0.089 12.2 3.7 0.35 10.3 1.8 2.0 2 0 0 2 2 2 0 ATP synthase (E/31 kDa) subunit Med4 PF10018.9 KFM23847.1 - 0.56 9.9 5.1 0.61 9.7 1.7 2.0 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 UbiA PF01040.18 KFM23848.1 - 2.3e-31 109.0 13.1 2.3e-29 102.4 11.9 2.3 1 1 0 1 1 1 1 UbiA prenyltransferase family GCV_T PF01571.21 KFM23850.1 - 5.9e-89 297.8 0.0 7.1e-89 297.6 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 KFM23850.1 - 7.7e-19 67.4 0.1 2.3e-18 65.9 0.1 1.9 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain DUF3464 PF11947.8 KFM23851.1 - 2.5e-34 118.2 0.0 2.9e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 Photosynthesis affected mutant 68 Flavodoxin_1 PF00258.25 KFM23852.1 - 2.6e-25 89.3 0.0 1.1e-24 87.2 0.0 2.1 3 0 0 3 3 3 1 Flavodoxin FAD_binding_1 PF00667.20 KFM23852.1 - 2.3e-23 83.0 0.0 1e-12 48.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain CPP1-like PF11833.8 KFM23852.1 - 3.1e-20 72.7 0.1 6.1e-20 71.7 0.1 1.5 1 0 0 1 1 1 1 Protein CHAPERONE-LIKE PROTEIN OF POR1-like NAD_binding_1 PF00175.21 KFM23852.1 - 4.8e-15 56.1 0.0 1.1e-14 55.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KFM23852.1 - 0.01 16.1 0.0 0.018 15.3 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin domain Peptidase_S41 PF03572.18 KFM23854.1 - 6.6e-43 146.2 0.1 9.7e-43 145.6 0.1 1.3 1 0 0 1 1 1 1 Peptidase family S41 PDZ_6 PF17820.1 KFM23854.1 - 1.3e-12 47.3 0.3 3.3e-12 46.0 0.3 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFM23854.1 - 1.1e-09 38.5 0.2 4.7e-09 36.4 0.1 2.2 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 KFM23854.1 - 6.4e-07 29.6 0.2 1.2e-06 28.7 0.2 1.5 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 KFM23854.1 - 0.0072 16.3 0.1 0.026 14.5 0.1 1.9 2 0 0 2 2 2 1 Tricorn protease PDZ domain Tricorn_C1 PF14684.6 KFM23854.1 - 0.013 15.6 0.2 0.029 14.4 0.0 1.6 2 0 0 2 2 2 0 Tricorn protease C1 domain Rhodanese PF00581.20 KFM23855.1 - 6.1e-09 36.4 0.0 3.4e-08 34.0 0.0 1.9 1 1 0 1 1 1 1 Rhodanese-like domain Tubulin PF00091.25 KFM23856.1 - 1.6e-41 142.7 0.7 3.2e-41 141.7 0.3 1.7 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.8 KFM23856.1 - 1.3e-31 108.7 1.6 3.4e-31 107.4 1.6 1.7 1 0 0 1 1 1 1 FtsZ family, C-terminal domain NAD_binding_10 PF13460.6 KFM23856.1 - 0.049 13.5 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H-binding Tubulin_2 PF13809.6 KFM23856.1 - 2.2 7.4 6.9 2.5 7.2 1.2 2.2 1 1 0 2 2 2 0 Tubulin like Metallophos PF00149.28 KFM23857.1 - 8.4e-14 52.5 0.1 1.6e-12 48.4 0.1 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFM23857.1 - 1.6e-09 38.2 0.0 1.2e-06 28.8 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain CDKN3 PF05706.12 KFM23858.1 - 0.006 16.3 0.2 0.0096 15.6 0.2 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) DSPc PF00782.20 KFM23858.1 - 0.011 15.6 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFM23858.1 - 0.16 11.5 0.1 0.24 10.9 0.1 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Methyltrans_RNA PF04452.14 KFM23858.1 - 0.16 11.3 0.0 0.22 10.8 0.0 1.1 1 0 0 1 1 1 0 RNA methyltransferase Y_phosphatase3 PF13350.6 KFM23858.1 - 0.25 11.3 0.8 0.36 10.7 0.8 1.3 1 1 0 1 1 1 0 Tyrosine phosphatase family SRR1 PF07985.12 KFM23859.1 - 5.7e-08 32.7 0.0 1.6e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 SRR1 U-box PF04564.15 KFM23859.1 - 0.00049 20.2 0.0 0.00089 19.4 0.0 1.4 1 0 0 1 1 1 1 U-box domain HEAT PF02985.22 KFM23859.1 - 0.6 10.5 0.0 0.6 10.5 0.0 3.3 4 0 0 4 4 4 0 HEAT repeat CAP_N PF01213.19 KFM23860.1 - 1.1 8.7 23.0 0.067 12.7 5.1 2.3 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 KFM23860.1 - 6.5 6.8 18.1 7.4 6.6 5.6 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator FA_desaturase PF00487.24 KFM23861.1 - 4.1e-33 115.3 20.6 6.8e-33 114.6 20.6 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KFM23861.1 - 1.4e-06 28.5 0.1 3.6e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) PET117 PF15786.5 KFM23862.1 - 4.3e-13 49.3 0.0 5.3e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial BRCA-2_OB1 PF09103.10 KFM23863.1 - 1.3e-21 76.8 0.0 3.6e-21 75.4 0.0 1.8 1 1 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA2 PF00634.18 KFM23863.1 - 1.4e-11 43.9 0.0 0.048 13.3 0.0 4.4 4 0 0 4 4 4 4 BRCA2 repeat BRCA-2_helical PF09169.10 KFM23863.1 - 0.00025 20.8 0.0 0.00048 19.8 0.0 1.3 1 0 0 1 1 1 1 BRCA2, helical DUF2007 PF09413.10 KFM23863.1 - 0.49 10.6 2.2 92 3.3 0.1 3.7 4 0 0 4 4 4 0 Putative prokaryotic signal transducing protein Ribosomal_60s PF00428.19 KFM23864.1 - 0.034 14.7 8.4 0.034 14.7 8.4 5.6 3 1 2 5 5 5 0 60s Acidic ribosomal protein GNAT_acetyltr_2 PF13718.6 KFM23864.1 - 0.035 13.5 0.1 0.056 12.8 0.1 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 CENP-T_C PF15511.6 KFM23865.1 - 2e-08 34.3 0.1 2.5e-08 34.0 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KFM23865.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KFM23865.1 - 0.00022 21.3 0.1 0.00031 20.8 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.13 KFM23865.1 - 0.0011 18.9 0.1 0.0017 18.4 0.1 1.2 1 0 0 1 1 1 1 Bromodomain associated CBFD_NFYB_HMF PF00808.23 KFM23865.1 - 0.0013 19.0 0.0 0.0022 18.3 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFM23865.1 - 0.0015 18.9 0.1 0.0017 18.8 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KFM23865.1 - 0.033 14.3 0.0 0.037 14.1 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 KFM23866.1 - 9.5e-52 174.8 2.5 1.3e-51 174.4 2.5 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 WD40 PF00400.32 KFM23866.1 - 6e-13 49.0 1.2 0.00027 21.7 0.0 3.5 3 0 0 3 3 3 3 WD domain, G-beta repeat CENP-T_C PF15511.6 KFM23866.1 - 0.0001 22.4 0.2 0.00023 21.2 0.2 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 KFM23866.1 - 0.00068 20.2 2.2 0.0014 19.2 2.2 1.5 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 KFM23866.1 - 0.00078 19.8 0.1 0.0016 18.8 0.1 1.5 1 0 0 1 1 1 1 CENP-S protein TPR_2 PF07719.17 KFM23866.1 - 0.00086 19.2 0.3 0.00086 19.2 0.3 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFM23866.1 - 0.0021 17.8 0.1 0.0068 16.2 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFM23866.1 - 0.0068 16.5 0.0 0.022 14.9 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat CBFD_NFYB_HMF PF00808.23 KFM23866.1 - 0.0082 16.4 0.1 0.017 15.4 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TPR_7 PF13176.6 KFM23866.1 - 0.025 14.6 0.9 0.1 12.7 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TFIID-31kDa PF02291.15 KFM23866.1 - 0.038 14.0 0.2 0.074 13.1 0.2 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TPR_11 PF13414.6 KFM23866.1 - 0.97 9.2 4.3 0.17 11.6 0.3 1.8 2 0 0 2 2 2 0 TPR repeat CnrY PF17524.2 KFM23866.1 - 1.7 8.9 6.2 0.45 10.8 2.3 2.0 1 1 0 2 2 2 0 Anti-sigma factor CnrY Nucleotid_trans PF03407.16 KFM23867.1 - 2.7e-35 122.3 0.0 3.6e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Nucleotid_trans PF03407.16 KFM23868.1 - 6.7e-42 143.9 0.7 8.6e-42 143.5 0.7 1.1 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DUF617 PF04759.13 KFM23868.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF617 Mur_ligase_M PF08245.12 KFM23869.1 - 2.7e-11 43.8 0.1 6.7e-11 42.5 0.1 1.7 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 KFM23869.1 - 9.7e-05 22.5 0.0 0.00028 21.1 0.0 1.9 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain PucR PF07905.11 KFM23869.1 - 0.033 14.5 1.6 0.065 13.5 0.1 2.3 3 0 0 3 3 3 0 Purine catabolism regulatory protein-like family A_deamin PF02137.18 KFM23870.1 - 6.6e-46 157.3 0.0 2.8e-43 148.6 0.0 2.2 1 1 1 2 2 2 2 Adenosine-deaminase (editase) domain TRAP-gamma PF07074.12 KFM23871.1 - 6.5 6.3 5.7 7.5 6.1 5.7 1.1 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) UQ_con PF00179.26 KFM23872.1 - 2.9e-37 127.4 0.0 6e-35 119.9 0.0 2.0 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFM23872.1 - 6.6e-07 29.1 0.1 9.5e-07 28.6 0.1 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B SUI1 PF01253.22 KFM23873.1 - 3.9e-20 72.1 2.5 1.6e-19 70.2 2.5 1.8 1 1 0 1 1 1 1 Translation initiation factor SUI1 Coatomer_WDAD PF04053.14 KFM23874.1 - 1.4e-115 386.9 0.0 2.5e-115 386.1 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 KFM23874.1 - 8.8e-37 124.5 4.2 5.7e-06 27.0 0.1 8.6 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM23874.1 - 1.5e-05 25.2 0.1 3.5 8.0 0.0 5.6 3 3 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Fe_bilin_red PF05996.12 KFM23876.1 - 1.5e-36 126.2 0.0 1.9e-36 125.9 0.0 1.1 1 0 0 1 1 1 1 Ferredoxin-dependent bilin reductase DEAD PF00270.29 KFM23878.1 - 3.1e-33 115.0 0.0 6.3e-33 114.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM23878.1 - 4.6e-31 107.4 0.0 1.3e-30 106.0 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM23878.1 - 5.7e-05 23.2 0.0 0.00011 22.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DnaI_N PF07319.11 KFM23878.1 - 0.064 13.9 0.3 0.15 12.8 0.1 1.7 2 0 0 2 2 2 0 Primosomal protein DnaI N-terminus ParA PF10609.9 KFM23879.1 - 2.6e-89 298.9 0.0 5.7e-83 278.1 0.2 2.0 1 1 1 2 2 2 2 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KFM23879.1 - 7.4e-14 51.9 0.0 9.2e-12 45.1 0.0 2.2 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KFM23879.1 - 9.1e-09 35.5 0.1 1.8e-07 31.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 KFM23879.1 - 1.5e-07 31.0 0.1 5e-07 29.3 0.1 1.8 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 KFM23879.1 - 3.5e-06 26.4 0.8 2.6e-05 23.5 0.1 2.3 2 1 1 3 3 3 1 Anion-transporting ATPase Fer4_NifH PF00142.18 KFM23879.1 - 0.00014 21.4 0.1 0.0049 16.4 0.1 2.4 3 0 0 3 3 3 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.6 KFM23879.1 - 0.0011 18.6 0.1 0.0026 17.4 0.1 1.7 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 KFM23879.1 - 0.0035 17.0 0.1 0.0085 15.7 0.0 1.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain MeaB PF03308.16 KFM23879.1 - 0.0037 16.3 0.1 0.0059 15.6 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CBP_BcsQ PF06564.12 KFM23879.1 - 0.0066 16.0 0.1 0.026 14.0 0.1 1.8 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ AAA_26 PF13500.6 KFM23879.1 - 0.012 15.5 0.2 0.55 10.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KFM23879.1 - 0.053 12.7 0.0 0.088 12.0 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain VirC1 PF07015.11 KFM23879.1 - 0.087 12.1 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 VirC1 protein APS_kinase PF01583.20 KFM23879.1 - 0.11 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase NACHT PF05729.12 KFM23879.1 - 0.21 11.5 0.3 0.33 10.9 0.3 1.3 1 0 0 1 1 1 0 NACHT domain MgtE PF01769.16 KFM23880.1 - 1.2e-17 64.5 7.6 1.6e-17 64.0 7.6 1.2 1 0 0 1 1 1 1 Divalent cation transporter DUF3611 PF12263.8 KFM23880.1 - 0.035 14.0 4.8 0.046 13.6 1.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3611) Ribosomal_S13_N PF08069.12 KFM23881.1 - 7e-29 99.7 0.1 1.4e-28 98.7 0.1 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 KFM23881.1 - 8.7e-15 54.7 0.5 1.5e-14 53.9 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 CD24 PF14984.6 KFM23882.1 - 1 9.6 2.9 0.45 10.8 0.7 1.5 2 0 0 2 2 2 0 CD24 protein DUF1754 PF08555.10 KFM23883.1 - 0.0061 17.3 12.2 0.021 15.6 12.2 2.0 1 1 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) Phage_Nu1 PF07471.12 KFM23883.1 - 0.061 13.1 1.9 0.066 13.0 1.9 1.2 1 0 0 1 1 1 0 Phage DNA packaging protein Nu1 Lyase_1 PF00206.20 KFM23884.1 - 1.1e-115 386.3 0.0 1.5e-115 385.9 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 KFM23884.1 - 1.8e-25 89.1 0.4 5.2e-25 87.6 0.1 2.0 2 0 0 2 2 2 1 Fumarase C C-terminus Ribosomal_L19 PF01245.20 KFM23885.1 - 3.4e-05 23.8 2.4 9e-05 22.4 2.3 1.7 1 1 0 1 1 1 1 Ribosomal protein L19 Thioredoxin PF00085.20 KFM23886.1 - 7.6e-20 70.8 0.0 6.8e-13 48.5 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin OST3_OST6 PF04756.13 KFM23886.1 - 0.00016 21.1 0.3 0.15 11.4 0.0 2.1 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family HyaE PF07449.11 KFM23886.1 - 0.00052 19.9 0.2 0.46 10.5 0.0 2.7 3 0 0 3 3 3 2 Hydrogenase-1 expression protein HyaE Thioredoxin_2 PF13098.6 KFM23886.1 - 0.0016 18.8 0.0 1.5 9.3 0.0 2.6 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KFM23886.1 - 0.0099 16.2 0.1 2.9 8.3 0.0 2.7 2 1 0 2 2 2 1 Thioredoxin-like NUDIX PF00293.28 KFM23886.1 - 0.88 9.6 4.3 4 7.5 1.4 2.2 2 0 0 2 2 2 0 NUDIX domain TPR_19 PF14559.6 KFM23887.1 - 0.01 16.3 1.6 0.13 12.8 0.0 2.9 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFM23887.1 - 0.48 11.1 6.6 0.55 10.9 3.8 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFM23887.1 - 0.71 10.9 6.5 11 7.1 1.4 3.2 1 1 2 3 3 3 0 Tetratricopeptide repeat ARD PF03079.14 KFM23888.1 - 2.2e-43 148.2 0.9 5.1e-43 147.0 0.9 1.5 1 1 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 KFM23888.1 - 7.5e-10 38.4 0.1 1.6e-09 37.4 0.1 1.5 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KFM23888.1 - 1.9e-06 27.8 0.1 3.6e-06 26.9 0.1 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 KFM23888.1 - 0.0039 16.8 0.0 0.0056 16.3 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_8 PF13621.6 KFM23888.1 - 0.018 14.8 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 Cupin-like domain Cupin_3 PF05899.12 KFM23888.1 - 0.089 12.5 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Rad51 PF08423.11 KFM23889.1 - 1.8e-22 79.8 0.0 2.3e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 Rad51 ATPase PF06745.13 KFM23889.1 - 5.7e-07 29.1 0.0 5.9e-07 29.1 0.0 1.3 1 1 0 1 1 1 1 KaiC RecA PF00154.21 KFM23889.1 - 0.00035 20.1 0.0 0.00093 18.7 0.0 1.6 2 0 0 2 2 2 1 recA bacterial DNA recombination protein PAXNEB PF05625.11 KFM23889.1 - 0.23 10.6 0.4 0.52 9.4 0.2 1.6 2 0 0 2 2 2 0 PAXNEB protein Patched PF02460.18 KFM23890.1 - 4.5e-73 246.7 0.1 7.9e-40 136.7 0.0 2.0 2 0 0 2 2 2 2 Patched family NPC1_N PF16414.5 KFM23890.1 - 4.4e-50 170.5 5.5 7.8e-50 169.7 5.5 1.3 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Sterol-sensing PF12349.8 KFM23890.1 - 1.3e-47 161.5 12.5 1.2e-45 155.1 0.4 2.5 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation Folate_rec PF03024.14 KFM23890.1 - 0.0088 15.9 2.7 0.0088 15.9 2.7 1.6 2 0 0 2 2 2 1 Folate receptor family ACR_tran PF00873.19 KFM23890.1 - 0.13 9.9 6.4 0.18 9.4 6.4 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Gpr1_Fun34_YaaH PF01184.19 KFM23891.1 - 5.7e-41 140.4 17.5 8.7e-41 139.8 17.5 1.2 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family CPP1-like PF11833.8 KFM23891.1 - 0.12 12.0 2.1 0.27 10.9 2.1 1.6 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like G-patch PF01585.23 KFM23892.1 - 4e-16 58.6 0.7 7.2e-16 57.8 0.7 1.4 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 KFM23892.1 - 0.0044 16.8 0.0 0.01 15.6 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.7 KFM23892.1 - 0.012 15.7 0.3 0.025 14.7 0.3 1.5 1 0 0 1 1 1 0 G-patch domain Ala_racemase_N PF01168.20 KFM23892.1 - 0.083 12.5 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Alanine racemase, N-terminal domain SET PF00856.28 KFM23893.1 - 1.7e-12 48.1 0.0 4e-12 46.8 0.0 1.7 1 1 0 1 1 1 1 SET domain Myb_DNA-binding PF00249.31 KFM23893.1 - 0.0018 18.5 0.1 0.016 15.4 0.0 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain SRPRB PF09439.10 KFM23894.1 - 2.3e-26 92.4 0.0 7.3e-25 87.4 0.0 2.0 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 KFM23894.1 - 1.6e-11 44.0 0.0 2.8e-07 30.2 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFM23894.1 - 2.4e-09 37.0 0.0 3.5e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFM23894.1 - 2.5e-08 34.0 0.0 3.7e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 KFM23894.1 - 0.00041 20.5 0.0 0.0057 16.9 0.0 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KFM23894.1 - 0.00063 19.0 0.0 0.068 12.3 0.0 2.4 2 1 0 2 2 2 1 G-protein alpha subunit AAA_29 PF13555.6 KFM23894.1 - 0.00064 19.4 0.1 0.0017 18.1 0.1 1.8 1 1 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KFM23894.1 - 0.00091 19.8 0.0 0.0024 18.4 0.0 1.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KFM23894.1 - 0.0012 18.8 0.0 0.0033 17.3 0.0 1.9 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KFM23894.1 - 0.0018 18.7 0.3 0.0034 17.8 0.3 1.8 1 1 0 1 1 1 1 AAA ATPase domain ATP_bind_1 PF03029.17 KFM23894.1 - 0.0021 17.9 0.0 1.1 9.0 0.1 2.1 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 KFM23894.1 - 0.0025 18.1 0.1 0.0057 16.9 0.1 1.7 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KFM23894.1 - 0.0029 18.1 0.0 0.0038 17.8 0.0 1.3 1 1 0 1 1 1 1 ABC transporter TniB PF05621.11 KFM23894.1 - 0.0046 16.4 0.0 0.29 10.5 0.0 2.2 2 0 0 2 2 2 1 Bacterial TniB protein DLIC PF05783.11 KFM23894.1 - 0.0066 15.3 0.0 0.013 14.3 0.0 1.4 2 0 0 2 2 2 1 Dynein light intermediate chain (DLIC) T2SSE PF00437.20 KFM23894.1 - 0.0073 15.4 0.1 0.011 14.8 0.1 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.29 KFM23894.1 - 0.01 16.3 0.0 0.074 13.5 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KFM23894.1 - 0.017 15.4 0.0 0.027 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 KFM23894.1 - 0.017 14.9 0.0 0.025 14.4 0.0 1.5 1 1 0 1 1 1 0 DEAD/DEAH box helicase Mg_chelatase PF01078.21 KFM23894.1 - 0.023 14.1 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KFM23894.1 - 0.025 15.1 0.0 0.041 14.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KFM23894.1 - 0.026 13.9 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family PduV-EutP PF10662.9 KFM23894.1 - 0.027 14.2 0.1 0.068 12.9 0.1 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 KFM23894.1 - 0.032 13.8 0.4 1 9.0 0.3 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RelB_transactiv PF16181.5 KFM23894.1 - 0.059 13.6 0.7 5.7 7.2 0.2 2.2 1 1 0 2 2 2 0 RelB transactivation domain AAA_7 PF12775.7 KFM23894.1 - 0.067 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KFM23894.1 - 0.11 12.2 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KFM23894.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KFM23894.1 - 0.12 12.1 0.0 0.54 10.0 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein Ras PF00071.22 KFM23894.1 - 0.14 11.7 0.0 12 5.5 0.0 2.1 2 0 0 2 2 2 0 Ras family RsgA_GTPase PF03193.16 KFM23894.1 - 0.18 11.7 0.1 0.96 9.3 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase Pentapeptide_2 PF01469.18 KFM23898.1 - 0.003 17.4 4.7 0.0064 16.3 4.7 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) DEAD PF00270.29 KFM23899.1 - 1.6e-47 161.5 0.2 3.8e-47 160.3 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM23899.1 - 4.9e-26 91.2 0.0 1.8e-25 89.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CRA_rpt PF07046.11 KFM23899.1 - 0.047 13.9 0.4 0.047 13.9 0.4 4.1 4 0 0 4 4 4 0 Cytoplasmic repetitive antigen (CRA) like repeat AAA_22 PF13401.6 KFM23899.1 - 0.072 13.4 0.3 0.35 11.1 0.1 2.3 1 1 1 2 2 2 0 AAA domain Acyl-CoA_dh_N PF02771.16 KFM23900.1 - 1.5e-34 119.0 0.0 3.7e-34 117.8 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 KFM23900.1 - 1.8e-34 119.1 1.7 8.3e-34 117.0 1.7 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KFM23900.1 - 2.5e-25 88.5 0.0 5.3e-25 87.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFM23900.1 - 8.6e-12 45.5 0.4 8.6e-12 45.5 0.4 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain WW PF00397.26 KFM23901.1 - 4.5e-23 81.0 7.9 1.4e-13 50.7 0.2 2.4 2 0 0 2 2 2 2 WW domain OTU PF02338.19 KFM23901.1 - 3.3e-11 43.8 0.0 8.3e-11 42.5 0.0 1.6 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KFM23901.1 - 0.029 13.8 0.0 4 6.8 0.0 2.1 1 1 1 2 2 2 0 Peptidase C65 Otubain Glyco_hyd_101C PF17451.2 KFM23901.1 - 0.085 13.1 2.3 0.91 9.8 0.1 2.3 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain UbiA PF01040.18 KFM23902.1 - 1.9e-33 115.8 26.3 2.4e-33 115.5 26.3 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family COX4_pro PF03626.14 KFM23902.1 - 0.056 13.9 1.3 0.056 13.9 1.3 2.3 2 1 0 2 2 2 0 Prokaryotic Cytochrome C oxidase subunit IV HIG_1_N PF04588.13 KFM23903.1 - 5.6e-21 74.5 2.9 5.6e-21 74.5 2.9 1.8 2 0 0 2 2 2 1 Hypoxia induced protein conserved region Peptidase_M66 PF10462.9 KFM23903.1 - 0.21 10.5 0.4 0.22 10.4 0.4 1.1 1 0 0 1 1 1 0 Peptidase M66 WD40 PF00400.32 KFM23907.1 - 3.1e-10 40.5 11.3 0.00033 21.4 0.1 5.8 3 2 2 5 5 5 3 WD domain, G-beta repeat PQQ_3 PF13570.6 KFM23907.1 - 0.032 14.7 3.6 14 6.3 0.0 4.5 3 1 0 3 3 3 0 PQQ-like domain Methyltransf_25 PF13649.6 KFM23908.1 - 2e-12 47.6 0.0 9.7e-12 45.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM23908.1 - 8.5e-12 45.7 0.0 2.4e-11 44.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM23908.1 - 2e-08 34.3 0.0 3.9e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFM23908.1 - 1.4e-07 32.1 0.0 2.8e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM23908.1 - 5.8e-06 26.2 0.0 1.3e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KFM23908.1 - 0.004 18.1 0.0 0.024 15.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KFM23908.1 - 0.17 11.4 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain VWA PF00092.28 KFM23909.1 - 6.2e-24 85.2 0.0 8.3e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KFM23909.1 - 1.8e-15 57.5 0.1 3.3e-15 56.6 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KFM23909.1 - 3.5e-05 23.3 0.4 8.2e-05 22.1 0.4 1.4 1 1 0 1 1 1 1 VWA domain containing CoxE-like protein VWA_3 PF13768.6 KFM23909.1 - 7.2e-05 22.8 0.1 0.00011 22.1 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain ABC_ATPase PF09818.9 KFM23910.1 - 1.3e-164 548.2 0.0 1.7e-164 547.9 0.0 1.0 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_23 PF13476.6 KFM23910.1 - 0.018 15.5 0.0 0.027 15.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain Alpha-amyl_C2 PF07821.12 KFM23911.1 - 2.4e-20 72.5 0.2 5.5e-20 71.4 0.2 1.6 1 0 0 1 1 1 1 Alpha-amylase C-terminal beta-sheet domain Alpha-amylase PF00128.24 KFM23911.1 - 7.2e-19 68.5 0.0 1.9e-18 67.2 0.0 1.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain ACT PF01842.25 KFM23911.1 - 0.0014 18.3 0.0 0.0033 17.2 0.0 1.6 1 0 0 1 1 1 1 ACT domain Glyco_hydro_70 PF02324.16 KFM23911.1 - 0.0023 16.2 0.0 0.0039 15.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 70 ATG16 PF08614.11 KFM23912.1 - 0.0048 17.1 5.2 0.0048 17.1 5.2 3.7 3 1 1 4 4 4 2 Autophagy protein 16 (ATG16) Fez1 PF06818.15 KFM23912.1 - 0.078 13.4 26.3 0.47 10.9 13.2 2.8 1 1 1 2 2 2 0 Fez1 SPATA24 PF15175.6 KFM23912.1 - 0.093 12.6 4.7 0.4 10.6 0.6 2.5 2 0 0 2 2 2 0 Spermatogenesis-associated protein 24 Herpes_BLRF2 PF05812.12 KFM23912.1 - 0.11 12.7 0.1 0.11 12.7 0.1 3.4 3 1 0 3 3 3 0 Herpesvirus BLRF2 protein YabA PF06156.13 KFM23912.1 - 0.52 11.0 10.6 3.6 8.3 1.1 3.6 2 1 1 3 3 3 0 Initiation control protein YabA OmpH PF03938.14 KFM23912.1 - 4.9 7.5 35.7 0.47 10.8 1.3 3.8 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) HAD_2 PF13419.6 KFM23913.1 - 5.4e-12 46.1 0.0 7e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFM23913.1 - 1.4e-11 44.3 0.1 3.7e-11 42.9 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 KFM23913.1 - 2.4e-08 34.5 0.0 3.2e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 KFM23913.1 - 0.027 14.1 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase S6PP PF05116.13 KFM23913.1 - 0.21 11.1 0.0 0.39 10.2 0.0 1.5 1 1 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase DnaJ PF00226.31 KFM23914.1 - 1.4e-18 66.8 0.0 2.7e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain ADH_zinc_N PF00107.26 KFM23914.1 - 1.4e-12 47.7 0.0 2.6e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFM23914.1 - 2.2e-06 27.5 0.0 4.6e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain CENP-F_leu_zip PF10473.9 KFM23915.1 - 0.003 17.6 3.4 0.003 17.6 3.4 3.1 1 1 2 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CAML PF14963.6 KFM23915.1 - 1.2 9.2 8.7 0.2 11.8 4.3 1.8 1 1 1 2 2 2 0 Calcium signal-modulating cyclophilin ligand AAA_13 PF13166.6 KFM23915.1 - 5.6 5.5 11.1 1.4 7.5 7.9 1.5 1 1 0 1 1 1 0 AAA domain Fez1 PF06818.15 KFM23915.1 - 7.3 7.0 26.8 1.5 9.2 11.8 2.6 2 1 1 3 3 3 0 Fez1 COG2 PF06148.11 KFM23915.1 - 9.5 6.3 11.8 2.2 8.4 1.2 3.7 3 1 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 GSHPx PF00255.19 KFM23916.1 - 1e-40 137.7 0.1 1.6e-40 137.1 0.1 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 KFM23916.1 - 6.6e-08 32.5 0.1 2.1e-06 27.7 0.1 2.2 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KFM23916.1 - 0.00014 21.6 0.1 0.0027 17.4 0.0 2.1 2 0 0 2 2 2 1 Redoxin HSF_DNA-bind PF00447.17 KFM23918.1 - 3.1e-28 98.2 0.2 4.6e-28 97.7 0.2 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding HALZ PF02183.18 KFM23918.1 - 0.01 16.0 0.0 0.016 15.4 0.0 1.2 1 0 0 1 1 1 0 Homeobox associated leucine zipper Ets PF00178.22 KFM23918.1 - 0.11 13.0 0.0 0.2 12.2 0.0 1.4 1 0 0 1 1 1 0 Ets-domain Peptidase_S10 PF00450.22 KFM23919.1 - 1.2e-101 341.1 0.0 1.5e-101 340.8 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase RabGAP-TBC PF00566.18 KFM23920.1 - 5.3e-28 98.1 0.0 9.7e-27 94.0 0.0 2.0 2 0 0 2 2 2 2 Rab-GTPase-TBC domain LRR_9 PF14580.6 KFM23921.1 - 4.1e-13 49.2 0.0 6.5e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 KFM23921.1 - 1e-05 25.7 8.2 0.11 12.9 0.3 3.9 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFM23921.1 - 0.00051 19.7 6.0 0.07 12.9 1.6 3.5 1 1 2 3 3 3 3 Leucine rich repeat BcsB PF03170.13 KFM23921.1 - 0.18 10.2 0.0 0.32 9.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial cellulose synthase subunit Ribosomal_S8e PF01201.22 KFM23922.1 - 8.8e-46 155.5 3.9 1.2e-45 155.0 3.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e DUF493 PF04359.14 KFM23923.1 - 4.6e-16 59.2 0.0 5.8e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF493) Ank_4 PF13637.6 KFM23924.1 - 1.4e-14 54.2 0.5 1.7e-06 28.5 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM23924.1 - 1.5e-12 47.9 0.3 1.1e-08 35.6 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KFM23924.1 - 1.8e-10 40.7 0.1 0.0027 18.1 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KFM23924.1 - 2.1e-08 33.8 0.0 0.022 15.3 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KFM23924.1 - 4.6e-08 33.2 0.2 0.00074 19.8 0.0 3.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) zf-C3HC4_3 PF13920.6 KFM23924.1 - 3.1e-06 27.0 8.3 3.1e-06 27.0 8.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PH PF00169.29 KFM23924.1 - 0.21 12.1 0.0 0.34 11.4 0.0 1.3 1 0 0 1 1 1 0 PH domain DUF2437 PF10370.9 KFM23928.1 - 0.082 13.8 14.0 0.22 12.5 1.2 4.9 3 2 0 3 3 3 0 Domain of unknown function (DUF2437) BCIP PF13862.6 KFM23931.1 - 1.7e-28 99.8 0.0 3e-27 95.8 0.0 2.0 1 1 0 1 1 1 1 p21-C-terminal region-binding protein PP2C PF00481.21 KFM23932.1 - 5.4e-32 111.4 0.0 7.6e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C FHA PF00498.26 KFM23932.1 - 8.7e-13 48.4 0.0 1.5e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KFM23932.1 - 4.3e-06 26.9 0.0 8.7e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain SpoIIE PF07228.12 KFM23932.1 - 0.0057 16.6 0.1 0.014 15.3 0.1 1.6 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) zf-RING_2 PF13639.6 KFM23934.1 - 3.8e-12 46.3 6.0 5.2e-12 45.9 6.0 1.2 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KFM23934.1 - 5.2e-10 39.5 8.5 1.2e-09 38.3 8.5 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KFM23934.1 - 1.1e-07 31.5 8.7 5.7e-07 29.3 9.5 1.7 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFM23934.1 - 2.3e-07 30.7 5.8 3.6e-07 30.1 5.8 1.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KFM23934.1 - 5.8e-07 29.5 1.8 7.2e-07 29.2 1.8 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 KFM23934.1 - 1.1e-06 28.4 7.3 1.8e-06 27.7 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM23934.1 - 3.9e-06 26.7 5.3 5.5e-06 26.2 5.3 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 KFM23934.1 - 6.6e-06 25.8 2.8 1.1e-05 25.0 2.8 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 KFM23934.1 - 9.1e-06 25.4 3.1 1.3e-05 24.9 3.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFM23934.1 - 0.00014 21.9 6.0 0.00036 20.6 6.0 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 KFM23934.1 - 0.0077 16.0 1.9 0.013 15.3 1.9 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit TerY_C PF15616.6 KFM23934.1 - 0.012 15.8 0.5 0.017 15.2 0.5 1.2 1 0 0 1 1 1 0 TerY-C metal binding domain Prok-RING_4 PF14447.6 KFM23934.1 - 0.012 15.5 6.0 0.11 12.3 6.6 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zinc_ribbon_9 PF14369.6 KFM23934.1 - 0.029 14.6 1.1 8.6 6.7 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon Zn_ribbon_17 PF17120.5 KFM23934.1 - 0.12 12.0 6.7 0.28 10.8 6.7 1.6 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KFM23934.1 - 0.12 12.2 3.5 4.8 7.1 1.8 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 KFM23934.1 - 0.21 11.8 8.4 3.7 7.8 8.4 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain zf-P11 PF03854.14 KFM23934.1 - 0.22 11.2 6.0 8.8 6.1 6.9 2.1 1 1 1 2 2 2 0 P-11 zinc finger zf-ribbon_3 PF13248.6 KFM23934.1 - 0.6 9.6 5.9 1.4 8.4 0.0 2.9 3 0 0 3 3 3 0 zinc-ribbon domain zf-C3H2C3 PF17122.5 KFM23934.1 - 1.5 8.9 11.3 3.9 7.6 5.9 2.5 2 1 0 2 2 2 0 Zinc-finger Mito_carr PF00153.27 KFM23936.1 - 4.1e-48 161.3 5.2 2.7e-19 68.9 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RBFA PF02033.18 KFM23937.1 - 8e-06 26.3 0.0 9.8e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Ribosome-binding factor A Vps39_2 PF10367.9 KFM23938.1 - 3e-19 69.5 0.0 1.5e-18 67.2 0.0 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 KFM23938.1 - 1.2e-15 57.7 0.0 1.1e-14 54.6 0.0 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.20 KFM23938.1 - 2.2e-09 37.3 0.0 0.00033 20.5 0.0 2.3 2 0 0 2 2 2 2 Region in Clathrin and VPS TPR_1 PF00515.28 KFM23938.1 - 0.0063 16.3 4.7 2 8.4 0.1 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFM23938.1 - 0.13 12.2 14.7 0.63 10.0 0.2 5.5 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFM23938.1 - 0.32 11.1 8.0 6.2 7.1 0.7 4.8 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFM23938.1 - 1.3 9.3 12.5 11 6.4 0.2 4.8 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFM23938.1 - 1.6 9.1 15.1 1.3 9.4 0.5 5.0 3 1 1 4 4 4 0 Tetratricopeptide repeat p450 PF00067.22 KFM23939.1 - 4.7e-81 272.9 0.0 5.9e-81 272.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Tctex-1 PF03645.13 KFM23940.1 - 1.4e-15 57.4 0.0 1.5e-15 57.2 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family Ribosomal_L27A PF00828.19 KFM23941.1 - 7.1e-12 46.1 2.3 1.2e-11 45.4 2.3 1.6 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A zf-C3HC4_3 PF13920.6 KFM23942.1 - 0.00011 22.0 0.8 0.00016 21.5 0.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFM23942.1 - 0.05 13.5 0.8 0.075 12.9 0.8 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Peptidase_M18 PF02127.15 KFM23943.1 - 1.1e-151 505.6 0.0 1.2e-151 505.4 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 KFM23943.1 - 0.00012 21.2 0.2 0.00053 19.1 0.0 2.0 2 1 0 2 2 2 1 M42 glutamyl aminopeptidase Tim17 PF02466.19 KFM23944.1 - 3.1e-07 30.7 11.4 4e-07 30.4 10.0 1.9 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family SAM_1 PF00536.30 KFM23944.1 - 0.0043 17.5 0.0 0.009 16.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DDOST_48kD PF03345.14 KFM23945.1 - 5.1e-100 335.2 0.0 5.7e-100 335.0 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta SEP PF08059.13 KFM23946.1 - 7e-20 71.4 0.0 1.4e-19 70.5 0.0 1.5 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 KFM23946.1 - 4.2e-11 42.9 0.0 7.2e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 KFM23946.1 - 1.2e-09 37.8 0.2 2.4e-09 36.9 0.2 1.5 1 0 0 1 1 1 1 UBA-like domain SET PF00856.28 KFM23947.1 - 0.00012 22.5 0.0 0.00019 21.9 0.0 1.3 1 0 0 1 1 1 1 SET domain Hva1_TUDOR PF11160.8 KFM23948.1 - 3.4e-16 59.2 3.0 4.6e-16 58.7 3.0 1.2 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain Hydrolase PF00702.26 KFM23949.1 - 4.8e-19 69.5 0.2 2.3e-18 67.3 0.2 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KFM23949.1 - 4.2e-10 39.5 0.5 4.2e-10 39.5 0.5 3.0 3 0 0 3 3 3 2 E1-E2 ATPase Hydrolase_3 PF08282.12 KFM23949.1 - 0.00021 21.1 0.3 0.0032 17.2 0.2 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFM23949.1 - 0.041 14.0 0.1 0.16 12.1 0.0 1.9 2 0 0 2 2 2 0 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KFM23950.1 - 5.2e-25 88.0 0.0 1.1e-24 86.9 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 KFM23950.1 - 2.3e-12 46.4 0.0 3.7e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus DUF3039 PF11238.8 KFM23951.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3039) Catalase PF00199.19 KFM23952.1 - 6.6e-169 562.0 0.0 7.8e-169 561.8 0.0 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KFM23952.1 - 5.6e-17 61.7 0.0 2.1e-16 59.9 0.0 2.0 2 0 0 2 2 2 1 Catalase-related immune-responsive Methyltransf_4 PF02390.17 KFM23953.1 - 8.6e-46 155.5 0.0 1.1e-45 155.2 0.0 1.0 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 KFM23953.1 - 3e-05 24.6 0.0 0.00018 22.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFM23953.1 - 0.00012 22.7 0.0 0.0069 17.0 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KFM23953.1 - 0.0055 16.3 0.0 0.019 14.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain DOT1 PF08123.13 KFM23953.1 - 0.015 14.8 0.0 0.025 14.1 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 RrnaAD PF00398.20 KFM23953.1 - 0.02 14.0 0.0 0.026 13.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase CMAS PF02353.20 KFM23953.1 - 0.034 13.4 0.0 0.064 12.5 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 KFM23953.1 - 0.061 14.1 0.0 0.18 12.5 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 KFM23953.1 - 0.061 13.1 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 KFM23953.1 - 0.077 13.0 0.0 0.098 12.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Gal-3-0_sulfotr PF06990.11 KFM23954.1 - 0.15 10.9 0.2 0.24 10.2 0.2 1.3 1 0 0 1 1 1 0 Galactose-3-O-sulfotransferase Rubis-subs-bind PF09273.11 KFM23955.1 - 1.4e-05 25.8 0.0 4e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding Mvb12 PF09452.10 KFM23955.1 - 0.13 12.8 0.0 0.36 11.3 0.0 1.7 2 0 0 2 2 2 0 ESCRT-I subunit Mvb12 dCMP_cyt_deam_1 PF00383.23 KFM23957.1 - 4.3e-08 33.0 0.5 8.6e-08 32.0 0.5 1.5 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KFM23957.1 - 0.0099 15.6 0.1 0.02 14.6 0.1 1.5 1 0 0 1 1 1 1 MafB19-like deaminase PAS_4 PF08448.10 KFM23957.1 - 0.014 15.6 0.5 0.34 11.2 0.1 2.4 2 0 0 2 2 2 0 PAS fold ECH_1 PF00378.20 KFM23958.1 - 1.3e-40 139.3 0.0 1.7e-40 138.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFM23958.1 - 6.1e-21 75.3 0.0 7.7e-21 74.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Atg14 PF10186.9 KFM23959.1 - 0.2 10.7 5.9 0.24 10.5 5.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ADIP PF11559.8 KFM23959.1 - 0.26 11.4 12.8 0.8 9.8 10.3 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 KFM23959.1 - 0.76 8.6 9.7 0.95 8.3 9.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Endostatin PF06482.11 KFM23959.1 - 1.8 8.0 6.0 6.1 6.2 1.3 2.0 1 1 1 2 2 2 0 Collagenase NC10 and Endostatin TPR_MLP1_2 PF07926.12 KFM23959.1 - 7.5 6.6 22.3 4.5 7.3 8.1 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 KFM23959.1 - 8.1 5.7 20.3 13 5.1 20.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sec7 PF01369.20 KFM23960.1 - 2.3e-50 170.8 0.0 3.5e-50 170.2 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KFM23960.1 - 2.2e-10 40.6 0.0 2.3e-09 37.4 0.0 2.4 2 1 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal IATP PF04568.12 KFM23961.1 - 0.00024 21.4 0.2 0.00033 21.0 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP RNase_H2-Ydr279 PF09468.10 KFM23961.1 - 0.13 12.5 0.1 0.15 12.2 0.1 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain EF_assoc_2 PF08356.12 KFM23962.1 - 1.4e-27 95.5 0.0 2.5e-27 94.7 0.0 1.4 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 KFM23962.1 - 1.3e-15 57.4 0.0 2.3e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Ras family EF_assoc_1 PF08355.12 KFM23962.1 - 1.3e-08 34.3 0.6 1.2e-07 31.2 0.4 2.2 2 0 0 2 2 2 1 EF hand associated Roc PF08477.13 KFM23962.1 - 1.6e-07 31.6 0.0 4e-07 30.3 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase EF-hand_6 PF13405.6 KFM23962.1 - 1.8e-06 27.4 1.2 0.0048 16.7 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KFM23962.1 - 3.3e-06 26.2 1.6 0.0011 18.3 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KFM23962.1 - 5.1e-06 26.8 0.0 0.012 16.0 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KFM23962.1 - 0.004 16.6 0.7 0.7 9.5 0.1 2.4 2 0 0 2 2 2 1 EF hand SPARC_Ca_bdg PF10591.9 KFM23962.1 - 0.0068 16.7 0.2 5.2 7.4 0.0 2.6 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 KFM23962.1 - 0.0079 16.0 1.0 0.72 9.8 0.1 2.3 2 0 0 2 2 2 1 EF hand AAA_16 PF13191.6 KFM23962.1 - 0.02 15.3 0.0 0.038 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 KFM23962.1 - 0.03 14.4 0.0 0.063 13.4 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA PF00004.29 KFM23962.1 - 0.053 13.9 0.0 0.085 13.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KFM23962.1 - 0.072 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KFM23962.1 - 0.076 13.3 0.0 0.59 10.4 0.0 2.2 1 1 1 2 2 2 0 AAA domain NACHT PF05729.12 KFM23962.1 - 0.13 12.1 0.1 2.1 8.3 0.0 2.3 1 1 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 KFM23962.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain GDP_Man_Dehyd PF16363.5 KFM23964.1 - 6.1e-61 206.7 0.0 1e-60 205.9 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KFM23964.1 - 2.1e-51 174.7 0.0 2.9e-51 174.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFM23964.1 - 2.1e-11 43.4 0.0 3.2e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KFM23964.1 - 6e-10 38.7 0.0 3.5e-07 29.6 0.0 2.5 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 KFM23964.1 - 1.2e-09 37.7 0.0 1.7e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain WD40 PF00400.32 KFM23964.1 - 4.5e-07 30.4 11.9 0.0037 18.1 0.4 5.8 6 0 0 6 6 6 2 WD domain, G-beta repeat Polysacc_synt_2 PF02719.15 KFM23964.1 - 1.1e-06 28.0 0.0 0.0021 17.3 0.0 2.5 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein ANAPC4_WD40 PF12894.7 KFM23964.1 - 0.008 16.5 0.0 1.7 9.0 0.0 3.3 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Cys_Met_Meta_PP PF01053.20 KFM23964.1 - 0.061 11.9 0.0 4 5.9 0.0 2.2 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme adh_short PF00106.25 KFM23964.1 - 0.091 12.2 0.0 0.28 10.6 0.0 1.8 2 0 0 2 2 2 0 short chain dehydrogenase Abhydrolase_1 PF00561.20 KFM23965.1 - 3.4e-15 56.4 0.0 7.4e-10 38.9 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFM23965.1 - 8.3e-15 54.7 0.0 1.3e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFM23965.1 - 1e-12 49.2 0.2 1.6e-12 48.5 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 KFM23965.1 - 0.00012 22.1 0.0 0.00034 20.7 0.0 1.7 2 0 0 2 2 2 1 TAP-like protein Peptidase_S9 PF00326.21 KFM23965.1 - 0.013 14.9 0.3 0.82 9.1 0.3 2.3 1 1 1 2 2 2 0 Prolyl oligopeptidase family Esterase PF00756.20 KFM23965.1 - 0.031 13.9 0.1 0.067 12.8 0.1 1.5 1 1 0 1 1 1 0 Putative esterase Abhydrolase_1 PF00561.20 KFM23966.1 - 1.2e-16 61.2 0.2 3.3e-15 56.4 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFM23966.1 - 2.6e-14 54.3 0.3 3.6e-14 53.9 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFM23966.1 - 2.6e-10 40.0 0.0 4e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KFM23966.1 - 0.00018 21.7 0.0 0.00034 20.8 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 KFM23966.1 - 0.0043 16.7 0.1 0.0085 15.8 0.1 1.5 1 0 0 1 1 1 1 Putative esterase Abhydrolase_4 PF08386.10 KFM23966.1 - 0.0097 16.0 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Peptidase_S9 PF00326.21 KFM23966.1 - 0.085 12.3 0.1 5 6.5 0.0 2.4 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KFM23966.1 - 0.092 12.5 0.0 0.79 9.5 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 KFM23967.1 - 3.2e-15 56.5 0.0 2.6e-13 50.2 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFM23967.1 - 5.1e-14 53.4 0.2 6.1e-14 53.2 0.2 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFM23967.1 - 4.8e-09 35.8 0.0 6.5e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KFM23967.1 - 8.9e-05 22.7 0.0 0.00039 20.6 0.0 1.8 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_4 PF08386.10 KFM23967.1 - 0.0011 19.0 0.0 0.0019 18.3 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Esterase PF00756.20 KFM23967.1 - 0.021 14.5 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.21 KFM23967.1 - 0.035 13.6 0.4 1.2 8.6 0.2 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family DLH PF01738.18 KFM23967.1 - 0.066 12.8 0.0 7.5 6.0 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family SSF PF00474.17 KFM23968.1 - 5.9e-07 28.7 25.1 1.7e-06 27.2 25.1 1.9 1 1 0 1 1 1 1 Sodium:solute symporter family Oxidored_molyb PF00174.19 KFM23969.1 - 3.4e-56 189.6 0.0 5.2e-56 188.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KFM23969.1 - 2.5e-37 127.9 0.1 5.6e-37 126.8 0.1 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 KFM23969.1 - 6.1e-16 58.3 0.0 1.3e-15 57.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FTO_CTD PF12934.7 KFM23970.1 - 0.077 12.8 0.1 0.077 12.8 0.1 1.1 1 0 0 1 1 1 0 FTO C-terminal domain Peptidase_C50 PF03568.17 KFM23971.1 - 8.8e-48 163.4 0.0 7.1e-46 157.1 0.0 2.1 1 1 1 2 2 2 2 Peptidase family C50 CHAT PF12770.7 KFM23971.1 - 0.0011 18.5 0.9 0.0041 16.6 0.1 2.3 2 0 0 2 2 2 1 CHAT domain OapA_N PF08525.11 KFM23971.1 - 0.0067 16.3 1.1 0.02 14.8 1.1 1.9 1 0 0 1 1 1 1 Opacity-associated protein A N-terminal motif ERCC3_RAD25_C PF16203.5 KFM23972.1 - 7.4e-102 339.8 0.0 1.1e-101 339.2 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 KFM23972.1 - 8.5e-34 116.4 0.0 1.5e-33 115.7 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM23972.1 - 1.7e-14 54.2 0.0 2.7e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFM23972.1 - 8.7e-10 38.9 0.1 2e-09 37.8 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KFM23972.1 - 7.7e-08 31.4 0.0 9.6e-08 31.1 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain SWI2_SNF2 PF18766.1 KFM23972.1 - 0.059 13.0 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase UQ_con PF00179.26 KFM23973.1 - 6.5e-37 126.3 0.0 7.8e-37 126.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFM23973.1 - 0.088 13.1 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 RWD domain QH-AmDH_gamma PF08992.11 KFM23974.1 - 0.14 12.2 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, gamma subunit Trypan_PARP PF05887.11 KFM23974.1 - 7.4 6.6 33.8 0.68 9.9 28.8 1.8 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) DPBB_1 PF03330.18 KFM23975.1 - 0.049 13.9 0.2 0.17 12.1 0.2 1.9 1 1 0 1 1 1 0 Lytic transglycolase DPBB_1 PF03330.18 KFM23976.1 - 0.068 13.5 2.4 0.1 12.9 1.1 2.0 2 1 0 2 2 2 0 Lytic transglycolase GLTP PF08718.11 KFM23977.1 - 1.5e-27 96.7 0.0 1.6e-27 96.6 0.0 1.0 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) GLTP PF08718.11 KFM23978.1 - 2.7e-22 79.6 0.2 1.1e-16 61.4 0.0 2.4 2 1 1 3 3 3 2 Glycolipid transfer protein (GLTP) E2F_TDP PF02319.20 KFM23979.1 - 2.3e-18 66.0 0.0 3.6e-10 39.8 0.0 2.2 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain GnRH PF00446.17 KFM23979.1 - 4 8.1 6.4 0.75 10.3 1.5 2.6 2 0 0 2 2 2 0 Gonadotropin-releasing hormone HATPase_c PF02518.26 KFM23980.1 - 5.7e-22 78.4 0.0 9.6e-22 77.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.7 KFM23980.1 - 1.4e-19 70.3 0.0 3e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 PAS domain HisKA PF00512.25 KFM23980.1 - 1.5e-15 57.0 0.2 6.2e-15 55.0 0.1 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 KFM23980.1 - 6.9e-11 42.3 0.0 9.1e-10 38.7 0.0 2.5 2 0 0 2 2 2 1 Response regulator receiver domain PAS PF00989.25 KFM23980.1 - 1.9e-08 34.3 0.0 3.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 KFM23980.1 - 1.4e-06 28.5 0.0 3.2e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 KFM23980.1 - 3.8e-05 23.9 0.0 0.00017 21.8 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 KFM23980.1 - 0.00051 20.0 0.0 0.0018 18.2 0.0 1.9 1 0 0 1 1 1 1 PAS domain HATPase_c_3 PF13589.6 KFM23980.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase PF00069.25 KFM23981.1 - 3.9e-48 164.1 0.0 5.8e-48 163.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM23981.1 - 4.9e-48 163.7 0.0 7e-48 163.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFM23981.1 - 0.0018 18.3 0.6 0.0064 16.4 0.5 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family CBM_3 PF00942.18 KFM23981.1 - 0.0079 16.6 0.0 0.023 15.1 0.0 1.8 2 0 0 2 2 1 1 Cellulose binding domain Haspin_kinase PF12330.8 KFM23981.1 - 0.036 13.0 0.0 0.053 12.5 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 KFM23981.1 - 0.04 13.2 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like stn_TNFRSF12A PF12191.8 KFM23981.1 - 0.086 13.1 2.8 0.44 10.8 0.6 2.7 3 0 0 3 3 3 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Kdo PF06293.14 KFM23981.1 - 0.2 11.0 0.1 0.31 10.4 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFM23981.1 - 0.27 10.8 0.0 0.41 10.2 0.0 1.2 1 0 0 1 1 1 0 RIO1 family DUF4381 PF14316.6 KFM23981.1 - 0.44 10.8 2.3 0.62 10.3 1.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) PRIMA1 PF16101.5 KFM23981.1 - 6.9 6.7 7.9 1 9.4 2.7 2.2 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 PHD PF00628.29 KFM23982.1 - 5.3e-09 35.8 6.6 5.3e-09 35.8 6.6 1.9 2 0 0 2 2 2 1 PHD-finger PHD_4 PF16866.5 KFM23982.1 - 0.55 10.4 7.1 1.7 8.8 7.1 1.9 1 0 0 1 1 1 0 PHD-finger PHD_2 PF13831.6 KFM23982.1 - 2.3 7.9 7.6 0.27 10.8 2.4 2.3 2 0 0 2 2 2 0 PHD-finger E1-E2_ATPase PF00122.20 KFM23983.1 - 2e-48 164.3 1.9 2e-48 164.3 1.9 3.1 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KFM23983.1 - 1.2e-45 155.4 4.9 2.5e-45 154.4 4.9 1.5 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KFM23983.1 - 1.5e-11 44.2 0.0 8e-05 22.6 0.0 2.4 2 0 0 2 2 2 2 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFM23983.1 - 3.9e-10 40.4 4.1 1.7e-06 28.4 1.0 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KFM23983.1 - 1.1e-06 28.2 0.0 4.3e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KFM23983.1 - 9e-06 25.6 1.1 1.4e-05 25.0 1.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ribosomal_L3 PF00297.22 KFM23983.1 - 0.0035 16.4 0.1 0.0089 15.0 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L3 Aminotran_5 PF00266.19 KFM23986.1 - 2.5e-15 56.3 0.0 6.5e-14 51.7 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-V MOSC_N PF03476.16 KFM23986.1 - 1.4e-13 50.7 0.0 3.3e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 KFM23986.1 - 3e-12 46.7 0.0 5.9e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 MOSC domain Glyco_hydro_32N PF00251.20 KFM23987.1 - 2e-48 165.6 0.0 1.1e-38 133.6 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KFM23987.1 - 3.7e-07 30.3 0.0 1.3e-06 28.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal Pkinase_Tyr PF07714.17 KFM23989.1 - 5.4e-54 183.2 0.0 2.2e-53 181.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM23989.1 - 7.3e-49 166.5 0.0 2e-48 165.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain PAN_4 PF14295.6 KFM23989.1 - 0.00073 19.4 11.8 0.0028 17.5 7.6 2.6 2 0 0 2 2 2 1 PAN domain TPP_enzyme_C PF02775.21 KFM23989.1 - 0.059 13.2 0.1 0.17 11.7 0.1 1.8 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain ABC1 PF03109.16 KFM23989.1 - 0.1 12.8 0.1 0.2 11.8 0.1 1.4 1 0 0 1 1 1 0 ABC1 family Pkinase_Tyr PF07714.17 KFM23991.1 - 2.9e-51 174.2 0.0 1.2e-50 172.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM23991.1 - 4e-46 157.5 0.0 9.9e-46 156.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain CcmD PF04995.14 KFM23991.1 - 0.031 14.3 0.9 0.068 13.3 0.9 1.6 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Kinase-like PF14531.6 KFM23991.1 - 0.031 13.6 0.0 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Cyt-b5 PF00173.28 KFM23992.1 - 2.9e-10 40.1 0.8 4.8e-10 39.4 0.8 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Fe-S_biosyn PF01521.20 KFM23993.1 - 2.2e-19 69.7 0.0 2.5e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis PrmA PF06325.13 KFM23994.1 - 4e-12 46.2 0.3 4.7e-12 45.9 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KFM23994.1 - 2.5e-11 43.4 0.2 6.4e-11 42.1 0.2 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KFM23994.1 - 1e-08 35.7 0.4 2.2e-08 34.7 0.4 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM23994.1 - 1.8e-08 34.3 0.1 2.3e-08 34.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KFM23994.1 - 9.5e-08 31.9 0.0 1.2e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.18 KFM23994.1 - 5.5e-05 22.9 1.9 0.0018 18.0 1.9 2.6 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.12 KFM23994.1 - 0.00013 22.5 0.1 0.00026 21.6 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM23994.1 - 0.00087 19.2 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KFM23994.1 - 0.0032 17.4 0.0 0.0041 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM23994.1 - 0.0053 17.5 0.5 0.025 15.3 0.5 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFM23994.1 - 0.0058 16.0 0.0 0.011 15.1 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 KFM23994.1 - 0.01 15.9 0.1 0.014 15.4 0.1 1.2 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 KFM23994.1 - 0.012 15.4 0.0 0.025 14.3 0.0 1.5 1 1 0 1 1 1 0 Met-10+ like-protein Methyltransf_16 PF10294.9 KFM23994.1 - 0.029 14.1 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase AviRa PF11599.8 KFM23994.1 - 0.041 13.3 0.1 0.59 9.5 0.0 2.0 1 1 1 2 2 2 0 RRNA methyltransferase AviRa DNA_methylase PF00145.17 KFM23994.1 - 0.044 13.1 0.1 0.063 12.6 0.1 1.1 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase FtsJ PF01728.19 KFM23994.1 - 0.045 13.9 0.1 0.067 13.3 0.1 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_15 PF09445.10 KFM23994.1 - 0.057 13.0 0.0 0.12 12.0 0.0 1.6 1 1 0 1 1 1 0 RNA cap guanine-N2 methyltransferase FmrO PF07091.11 KFM23994.1 - 0.087 12.4 0.4 0.27 10.8 0.3 1.8 1 1 1 2 2 2 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_8 PF05148.15 KFM23994.1 - 0.18 11.6 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase ABC_tran PF00005.27 KFM23995.1 - 2.1e-41 141.6 0.0 3.3e-23 82.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KFM23995.1 - 4.4e-35 121.7 13.8 1.1e-25 90.8 5.7 2.8 2 1 0 2 2 2 2 ABC transporter transmembrane region MMR_HSR1 PF01926.23 KFM23995.1 - 0.00049 20.1 1.7 0.77 9.9 0.1 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 KFM23995.1 - 0.00054 19.9 1.7 2.2 8.0 0.0 3.5 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFM23995.1 - 0.00057 19.6 0.9 0.66 9.8 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KFM23995.1 - 0.0027 18.1 6.8 0.35 11.2 0.1 3.0 2 1 0 3 3 3 2 AAA ATPase domain DUF87 PF01935.17 KFM23995.1 - 0.0055 16.8 4.4 1 9.4 0.5 2.2 2 0 0 2 2 2 2 Helicase HerA, central domain SMC_N PF02463.19 KFM23995.1 - 0.016 14.7 1.2 27 4.1 0.1 3.5 4 0 0 4 4 4 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KFM23995.1 - 0.017 15.4 1.3 6.5 7.0 0.1 2.5 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KFM23995.1 - 0.024 14.6 1.4 4.7 7.1 0.3 2.3 2 0 0 2 2 2 0 RsgA GTPase Dynamin_N PF00350.23 KFM23995.1 - 0.027 14.5 4.5 0.47 10.5 1.5 2.3 2 0 0 2 2 2 0 Dynamin family Trigger_C PF05698.14 KFM23998.1 - 1.4e-13 51.1 3.4 7.5e-13 48.8 1.4 2.4 2 0 0 2 2 2 1 Bacterial trigger factor protein (TF) C-terminus Trigger_N PF05697.13 KFM23998.1 - 1.1e-11 45.2 0.0 2.2e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Bacterial trigger factor protein (TF) PTN13_u3 PF16599.5 KFM23998.1 - 0.093 12.8 0.2 0.15 12.1 0.2 1.3 1 0 0 1 1 1 0 Unstructured linker region on PTN13 protein between PDZ Tim44 PF04280.15 KFM23999.1 - 7.8e-20 71.5 0.0 1.1e-19 70.9 0.0 1.1 1 0 0 1 1 1 1 Tim44-like domain MBA1 PF07961.11 KFM23999.1 - 2.9e-08 33.1 0.0 3.7e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 MBA1-like protein Lipase_3 PF01764.25 KFM24000.1 - 8.1e-08 32.2 0.0 1.5e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Ribosomal_S19e PF01090.19 KFM24002.1 - 1.8e-52 176.7 0.0 2.3e-52 176.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e HrcA_DNA-bdg PF03444.15 KFM24002.1 - 0.0019 17.8 0.0 0.0037 16.9 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix transcription repressor, HrcA DNA-binding FaeA PF04703.12 KFM24002.1 - 0.04 14.3 0.1 0.17 12.3 0.0 2.1 3 0 0 3 3 3 0 FaeA-like protein BLACT_WH PF17778.1 KFM24002.1 - 0.051 13.6 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Beta-lactamase associated winged helix domain AAA_assoc_2 PF16193.5 KFM24002.1 - 0.12 12.7 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA C-terminal domain SKA1 PF07160.12 KFM24003.1 - 6.9e-44 150.5 0.0 9.3e-44 150.1 0.0 1.2 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 GalKase_gal_bdg PF10509.9 KFM24004.1 - 8.7e-21 73.2 0.1 1.9e-20 72.1 0.1 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 KFM24004.1 - 7.6e-15 54.9 1.6 7.6e-15 54.9 1.6 2.5 3 0 0 3 3 3 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KFM24004.1 - 1.9e-13 50.6 0.1 6.7e-13 48.8 0.1 2.0 1 0 0 1 1 1 1 GHMP kinases C terminal DUF3180 PF11377.8 KFM24004.1 - 0.64 10.2 0.0 0.64 10.2 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3180) DUF4592 PF15262.6 KFM24005.1 - 0.052 14.2 0.0 0.093 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4592) Ribosomal_L17 PF01196.19 KFM24006.1 - 2.1e-32 111.9 0.5 2.4e-32 111.7 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L17 TBP PF00352.21 KFM24008.1 - 3e-69 229.0 0.2 1.8e-33 114.3 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KFM24008.1 - 9.7e-05 22.4 0.0 0.55 10.4 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) RRM_1 PF00076.22 KFM24009.1 - 1.3e-33 114.6 0.0 4.2e-19 68.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KFM24009.1 - 0.0032 17.7 0.2 0.75 10.0 0.0 3.2 3 1 1 4 4 4 1 Cytosolic domain of 10TM putative phosphate transporter DUF4140 PF13600.6 KFM24009.1 - 0.061 13.8 0.7 0.42 11.1 0.0 2.6 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) Nup35_RRM_2 PF14605.6 KFM24009.1 - 0.089 12.8 0.0 2.8 8.0 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KFM24009.1 - 0.14 12.3 0.0 3 8.0 0.0 2.5 2 1 0 2 2 2 0 RNA recognition motif CCDC106 PF15794.5 KFM24009.1 - 1.6 8.4 10.4 4.3 7.0 10.6 1.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 Presenilin PF01080.17 KFM24009.1 - 3 6.5 5.1 3.5 6.3 5.1 1.1 1 0 0 1 1 1 0 Presenilin TraV PF09676.10 KFM24009.1 - 8 7.5 9.4 89 4.1 8.3 2.3 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) Pkinase PF00069.25 KFM24010.1 - 5e-63 212.9 0.0 6.3e-63 212.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM24010.1 - 1.1e-27 97.0 0.0 1.5e-27 96.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 KFM24010.1 - 0.13 11.9 0.0 0.84 9.2 0.0 2.0 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Hep_59 PF07052.11 KFM24011.1 - 1.6e-13 51.3 2.8 1.8e-13 51.2 0.1 2.4 3 0 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 DUF711 PF05167.12 KFM24012.1 - 9.7e-64 215.7 0.2 1.3e-63 215.3 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised ACR (DUF711) Alg14 PF08660.11 KFM24014.1 - 3.7e-57 193.0 0.0 4.3e-57 192.9 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like HrpB1_HrpK PF09613.10 KFM24017.1 - 2.3 7.9 5.5 2 8.1 0.0 2.7 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) HSP90 PF00183.18 KFM24018.1 - 1.2e-165 552.4 2.4 1.6e-159 532.1 1.2 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c PF02518.26 KFM24018.1 - 3.2e-13 50.1 0.1 5.9e-13 49.3 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KFM24018.1 - 1.5e-11 44.2 0.3 3.2e-11 43.2 0.3 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2240 PF09999.9 KFM24018.1 - 0.084 12.5 0.0 2.8 7.6 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2240) Epimerase PF01370.21 KFM24019.1 - 7.9e-18 64.8 0.0 8.6e-17 61.4 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFM24019.1 - 5.3e-17 62.2 0.0 5.3e-16 58.9 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RNase_T PF00929.24 KFM24019.1 - 3.7e-06 27.6 0.0 8.9e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Exonuclease EloA-BP1 PF15870.5 KFM24019.1 - 0.014 15.6 0.0 0.024 14.9 0.0 1.3 1 0 0 1 1 1 0 ElonginA binding-protein 1 GTP_EFTU PF00009.27 KFM24025.1 - 6.1e-59 198.8 0.0 8.2e-59 198.4 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KFM24025.1 - 1.3e-29 102.7 0.0 3.1e-29 101.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KFM24025.1 - 4.1e-18 65.5 6.6 9.7e-18 64.3 6.6 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFM24025.1 - 1.2e-05 25.3 0.0 2.1e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 KFM24025.1 - 0.0021 17.7 0.1 0.036 13.6 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 KFM24025.1 - 0.015 15.0 0.1 5.9 6.6 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 KFM24025.1 - 0.031 14.2 0.0 0.094 12.6 0.0 1.8 1 1 0 1 1 1 0 RsgA GTPase Lsm_C PF14894.6 KFM24025.1 - 0.06 13.1 4.9 0.12 12.1 4.9 1.5 1 0 0 1 1 1 0 Lsm C-terminal FeoB_N PF02421.18 KFM24025.1 - 0.067 12.7 1.0 1.7 8.1 1.0 2.7 1 1 0 1 1 1 0 Ferrous iron transport protein B Ank_2 PF12796.7 KFM24026.1 - 2e-15 57.1 0.0 2.5e-09 37.6 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFM24026.1 - 4.5e-15 54.2 0.0 0.012 16.1 0.0 5.8 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 KFM24026.1 - 7.8e-14 51.6 0.6 9.2e-07 29.0 0.0 4.2 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFM24026.1 - 2.7e-13 50.1 0.0 0.0022 18.5 0.0 5.1 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 KFM24026.1 - 3.1e-13 49.5 6.9 0.0028 18.0 0.0 6.5 7 0 0 7 7 7 3 Ankyrin repeat QRPTase_C PF01729.19 KFM24027.1 - 2.3e-52 177.2 2.6 3.2e-52 176.7 2.6 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain RRM_1 PF00076.22 KFM24027.1 - 1.1e-39 134.0 0.0 1.9e-19 69.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) QRPTase_N PF02749.16 KFM24027.1 - 4.3e-24 84.4 0.5 9.9e-22 76.8 0.1 2.4 2 0 0 2 2 2 2 Quinolinate phosphoribosyl transferase, N-terminal domain RRM_7 PF16367.5 KFM24027.1 - 3.9e-06 26.9 0.1 0.0024 17.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif OB_RNB PF08206.11 KFM24027.1 - 0.0046 16.6 0.2 0.057 13.1 0.2 2.3 2 0 0 2 2 2 1 Ribonuclease B OB domain RRM_5 PF13893.6 KFM24027.1 - 0.073 12.7 0.0 0.21 11.2 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ysc84 PF04366.12 KFM24027.1 - 0.13 12.0 2.0 6.4 6.5 0.2 2.5 1 1 1 2 2 2 0 Las17-binding protein actin regulator GRIP PF01465.20 KFM24028.1 - 2.3e-10 40.2 0.0 5e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 GRIP domain ATG16 PF08614.11 KFM24028.1 - 0.0001 22.6 142.4 0.0074 16.5 8.7 8.2 2 1 6 8 8 8 6 Autophagy protein 16 (ATG16) Spc7 PF08317.11 KFM24028.1 - 0.0036 16.2 6.2 0.0036 16.2 6.2 7.5 3 1 4 7 7 7 3 Spc7 kinetochore protein NblA PF04485.12 KFM24028.1 - 0.085 13.3 0.1 0.085 13.3 0.1 3.3 2 0 0 2 2 2 0 Phycobilisome degradation protein nblA HSBP1 PF06825.12 KFM24028.1 - 0.41 10.6 3.3 29 4.6 0.1 3.8 4 0 0 4 4 4 0 Heat shock factor binding protein 1 Shugoshin_N PF07558.11 KFM24028.1 - 1.3 9.0 9.7 3.6 7.5 1.3 3.9 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region Fez1 PF06818.15 KFM24028.1 - 3.7 7.9 90.3 0.4 11.1 1.5 6.8 2 1 2 4 4 4 0 Fez1 Aa_trans PF01490.18 KFM24029.1 - 3.1e-60 204.0 5.8 2.7e-37 128.5 5.1 2.2 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein WAC_Acf1_DNA_bd PF10537.9 KFM24030.1 - 8e-16 58.4 0.0 8e-16 58.4 0.0 2.6 3 0 0 3 3 3 1 ATP-utilising chromatin assembly and remodelling N-terminal DUF2054 PF10218.9 KFM24030.1 - 6.7e-09 35.9 6.7 2.5e-05 24.4 2.4 2.6 1 1 1 2 2 2 2 Uncharacterized conserved protein (DUF2054) WSD PF15613.6 KFM24030.1 - 0.0026 18.2 8.4 0.0093 16.4 0.3 3.6 3 1 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif FAST_1 PF06743.15 KFM24031.1 - 6.2e-05 22.9 0.0 0.021 14.7 0.0 3.2 3 0 0 3 3 3 2 FAST kinase-like protein, subdomain 1 Rad60-SLD PF11976.8 KFM24032.1 - 1e-20 73.3 0.1 1.3e-20 73.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KFM24032.1 - 3.1e-08 33.3 0.0 4.5e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Aldose_epim PF01263.20 KFM24032.1 - 0.091 12.1 0.0 0.1 11.9 0.0 1.0 1 0 0 1 1 1 0 Aldose 1-epimerase 2OG-FeII_Oxy_3 PF13640.6 KFM24033.1 - 2.2e-19 70.1 0.0 3.4e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ShK PF01549.24 KFM24033.1 - 0.00036 21.0 6.1 0.0015 19.0 6.1 2.1 1 1 0 1 1 1 1 ShK domain-like NCA2 PF08637.10 KFM24034.1 - 3.9e-38 131.3 0.0 6.1e-38 130.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 Proteasome PF00227.26 KFM24035.1 - 2.1e-45 154.5 0.1 2.7e-45 154.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit FAM91_N PF14647.6 KFM24037.1 - 7.3e-66 222.6 0.0 2.1e-45 155.4 0.0 2.1 1 1 1 2 2 2 2 FAM91 N-terminus FAM91_C PF14648.6 KFM24037.1 - 2.6e-35 122.1 0.0 1.1e-32 113.4 0.0 2.1 2 0 0 2 2 2 2 FAM91 C-terminus BCMA-Tall_bind PF09257.10 KFM24037.1 - 1.1 9.4 4.9 0.62 10.2 0.2 2.5 2 0 0 2 2 2 0 BCMA, TALL-1 binding RhoGAP PF00620.27 KFM24038.1 - 0.00041 20.2 0.0 0.088 12.6 0.0 2.1 1 1 1 2 2 2 2 RhoGAP domain Glyco_transf_15 PF01793.16 KFM24039.1 - 1.4e-94 317.1 0.0 1.7e-94 316.8 0.0 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase CSN8_PSD8_EIF3K PF10075.9 KFM24040.1 - 2.7e-23 82.5 0.0 3.2e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 KFM24040.1 - 0.0034 16.8 0.0 0.0039 16.6 0.0 1.0 1 0 0 1 1 1 1 SAC3/GANP family PCI PF01399.27 KFM24040.1 - 0.011 16.3 0.0 0.015 15.8 0.0 1.3 1 1 0 1 1 1 0 PCI domain Ala_racemase_N PF01168.20 KFM24042.1 - 1.4e-16 60.8 0.0 1.6e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Pro_isomerase PF00160.21 KFM24043.1 - 0.073 13.3 0.0 0.17 12.2 0.0 1.5 1 1 0 1 1 1 0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Maf1 PF09174.10 KFM24044.1 - 1.3e-44 152.4 0.0 1.8e-44 152.0 0.0 1.2 1 0 0 1 1 1 1 Maf1 regulator DUF98 PF01947.16 KFM24044.1 - 0.019 14.9 0.0 0.033 14.2 0.0 1.5 1 0 0 1 1 1 0 p-hydroxybenzoic acid synthase Rhodanese_C PF12368.8 KFM24045.1 - 3.3e-17 62.6 2.9 6.2e-17 61.7 2.9 1.5 1 0 0 1 1 1 1 Rhodanase C-terminal UPF0176_N PF17773.1 KFM24045.1 - 1.5e-15 57.3 0.0 2.6e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese PF00581.20 KFM24045.1 - 2.6e-10 40.8 0.0 5.4e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain GCH_III PF05165.12 KFM24045.1 - 0.2 10.9 2.4 0.32 10.2 1.9 1.6 1 1 0 1 1 1 0 GTP cyclohydrolase III Inositol_P PF00459.25 KFM24046.1 - 4.4e-69 233.0 0.0 6.2e-69 232.5 0.0 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family F-box-like PF12937.7 KFM24046.1 - 4.6e-14 52.0 2.6 5.4e-14 51.8 1.2 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KFM24046.1 - 6.6e-09 35.4 1.0 1.1e-08 34.8 0.3 1.7 2 0 0 2 2 2 1 F-box domain DUF4972 PF16342.5 KFM24047.1 - 0.0059 16.3 0.1 0.0078 15.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4972) SARAF PF06682.12 KFM24047.1 - 0.012 15.3 0.0 0.012 15.3 0.0 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF5320 PF17253.2 KFM24047.1 - 0.18 12.9 0.3 0.33 12.1 0.2 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5320) DASH_Hsk3 PF08227.11 KFM24047.1 - 0.4 11.1 2.7 0.63 10.4 2.7 1.3 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like Rad51 PF08423.11 KFM24048.1 - 4e-20 72.2 0.0 4.7e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KFM24048.1 - 1.2e-09 38.0 0.4 2.9e-09 36.8 0.1 1.7 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 KFM24048.1 - 8.2e-07 28.6 0.0 4.2e-06 26.3 0.0 2.1 3 0 0 3 3 3 1 KaiC RecA PF00154.21 KFM24048.1 - 0.00014 21.5 0.0 0.0014 18.1 0.0 2.0 2 0 0 2 2 2 1 recA bacterial DNA recombination protein DnaB_C PF03796.15 KFM24048.1 - 0.00018 20.9 0.0 0.0013 18.1 0.0 2.0 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_24 PF13479.6 KFM24048.1 - 0.0037 17.0 0.0 0.006 16.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KFM24048.1 - 0.042 13.6 0.0 0.087 12.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein 2-Hacid_dh_C PF02826.19 KFM24049.1 - 3.3e-40 137.3 0.0 5.5e-40 136.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Metallophos PF00149.28 KFM24049.1 - 2.7e-18 67.2 0.1 5.9e-18 66.1 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase NAD_binding_2 PF03446.15 KFM24049.1 - 3.9e-06 27.1 0.0 7e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 KFM24049.1 - 0.015 15.0 0.1 0.029 14.0 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 KFM24049.1 - 0.051 13.5 0.0 0.089 12.8 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Metallophos_2 PF12850.7 KFM24049.1 - 0.067 13.4 0.0 2.3 8.4 0.0 2.2 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain 3HCDH_N PF02737.18 KFM24049.1 - 0.25 11.2 0.0 0.42 10.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CTP_transf_1 PF01148.20 KFM24050.1 - 0.023 14.5 3.6 0.026 14.3 2.1 2.1 1 1 0 1 1 1 0 Cytidylyltransferase family tRNA-synt_1g PF09334.11 KFM24052.1 - 3.3e-148 493.6 0.0 4e-148 493.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA_bind PF01588.20 KFM24052.1 - 6e-10 39.1 0.0 1.1e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain tRNA-synt_1 PF00133.22 KFM24052.1 - 5.7e-08 31.5 0.0 2.7e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KFM24052.1 - 0.012 15.6 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KFM24052.1 - 0.1 11.9 0.0 0.26 10.6 0.0 1.6 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain DZR PF12773.7 KFM24052.1 - 0.35 10.9 2.1 0.84 9.7 2.1 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.6 KFM24052.1 - 2 7.9 3.9 31 4.2 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain tRNA_bind PF01588.20 KFM24053.1 - 1.5e-12 47.4 0.0 2.1e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Putative tRNA binding domain Aldo_ket_red PF00248.21 KFM24054.1 - 1.3e-77 260.9 0.0 1.2e-46 159.3 0.0 5.0 3 2 1 4 4 4 4 Aldo/keto reductase family Pkinase PF00069.25 KFM24055.1 - 3.2e-39 134.9 0.0 3.7e-38 131.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM24055.1 - 3.3e-37 128.2 0.0 2e-36 125.6 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFM24055.1 - 1.6 8.6 11.9 0.47 10.3 3.7 3.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family Arm PF00514.23 KFM24055.1 - 7.8 6.7 8.4 61 3.9 0.0 4.5 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Pkinase_Tyr PF07714.17 KFM24056.1 - 3.5e-38 131.4 0.0 1.3e-28 100.0 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KFM24056.1 - 8.3e-36 123.7 0.0 1.7e-29 103.0 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Arm_2 PF04826.13 KFM24056.1 - 0.0071 15.8 0.0 0.031 13.8 0.0 1.8 2 0 0 2 2 2 1 Armadillo-like CRM1_C PF08767.11 KFM24057.1 - 2.3e-117 391.8 1.6 2.3e-117 391.8 1.6 2.8 2 1 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.12 KFM24057.1 - 7.8e-39 133.1 1.2 1.2e-37 129.2 0.2 3.3 3 1 1 4 4 4 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 KFM24057.1 - 4.4e-32 109.5 1.0 1.9e-31 107.5 0.8 2.2 2 0 0 2 2 2 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 KFM24057.1 - 1.8e-25 88.8 1.3 3.7e-25 87.8 0.4 2.1 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 KFM24057.1 - 1.6e-17 62.7 0.6 4.4e-17 61.3 0.6 1.9 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 KFM24057.1 - 4.8e-14 52.0 0.2 1.9e-13 50.1 0.2 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Sec7_N PF12783.7 KFM24057.1 - 7.3e-06 26.0 7.6 0.058 13.3 0.0 5.1 4 1 2 6 6 6 3 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF3385 PF11865.8 KFM24057.1 - 0.074 13.0 3.6 0.88 9.5 0.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF3385) Adaptin_N PF01602.20 KFM24057.1 - 0.099 11.2 0.1 0.33 9.5 0.1 1.9 1 0 0 1 1 1 0 Adaptin N terminal region Aminotran_1_2 PF00155.21 KFM24058.1 - 3.4e-37 128.5 0.0 4.3e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KFM24058.1 - 0.051 12.1 0.0 0.076 11.5 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme HLH PF00010.26 KFM24060.1 - 6.1e-07 29.3 0.6 1.1e-06 28.5 0.0 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain APAF1_C PF17908.1 KFM24060.1 - 0.012 15.6 0.3 0.018 15.0 0.3 1.2 1 0 0 1 1 1 0 APAF-1 helical domain DUF3053 PF11254.8 KFM24060.1 - 0.038 13.6 1.0 0.047 13.3 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) ZapB PF06005.12 KFM24060.1 - 0.041 14.3 7.3 0.041 14.3 7.3 1.7 2 0 0 2 2 2 0 Cell division protein ZapB HAD PF12710.7 KFM24060.1 - 0.071 13.5 0.1 0.091 13.2 0.1 1.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DASH_Duo1 PF08651.10 KFM24060.1 - 0.073 12.9 0.9 0.12 12.2 0.9 1.3 1 0 0 1 1 1 0 DASH complex subunit Duo1 IFT20 PF14931.6 KFM24060.1 - 0.12 12.6 3.4 0.15 12.2 3.4 1.1 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 Ldh_1_N PF00056.23 KFM24061.1 - 8.5e-34 116.7 0.5 1.2e-33 116.2 0.5 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KFM24061.1 - 4.4e-33 114.6 0.0 7.2e-33 113.9 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 KFM24061.1 - 0.09 11.8 0.0 0.23 10.4 0.0 1.6 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family RNase_PH PF01138.21 KFM24062.1 - 2.4e-16 60.4 0.0 3.9e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KFM24062.1 - 2.1e-08 34.1 0.0 4.1e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 BACON PF13004.7 KFM24063.1 - 5.6 7.0 6.6 1.1e+02 2.9 0.3 3.7 3 1 0 3 3 3 0 Putative binding domain, N-terminal Glyco_hydro_9 PF00759.19 KFM24064.1 - 1.7e-72 245.1 12.9 2.2e-72 244.8 12.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Glyco_tranf_2_3 PF13641.6 KFM24064.1 - 1.1e-18 67.9 0.0 1.8e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KFM24064.1 - 3.1e-17 63.2 3.2 3.1e-17 63.2 3.2 3.8 2 1 1 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KFM24064.1 - 1.8e-09 37.6 0.0 3.1e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KFM24064.1 - 2e-08 33.9 0.0 1.3e-07 31.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Cellulose_synt PF03552.14 KFM24064.1 - 1.8e-07 30.1 2.4 0.00015 20.4 0.7 2.2 1 1 1 2 2 2 2 Cellulose synthase Tox-REase-3 PF15647.6 KFM24065.1 - 0.13 12.5 0.0 0.17 12.2 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 3 Glyco_transf_90 PF05686.12 KFM24066.1 - 2.7e-32 112.2 0.0 7.2e-28 97.6 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 90 BLOC1_2 PF10046.9 KFM24067.1 - 7.7 6.9 11.3 3.6 7.9 0.0 4.8 6 0 0 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 KFM24067.1 - 9.9 4.9 53.8 0.027 13.4 5.3 3.8 2 1 2 4 4 4 0 Spc7 kinetochore protein Peptidase_C13 PF01650.18 KFM24068.1 - 1.7e-91 306.3 0.0 2.5e-91 305.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.22 KFM24068.1 - 0.0013 18.8 0.0 0.0018 18.3 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Metallophos_2 PF12850.7 KFM24069.1 - 1.8e-30 106.3 0.5 2.3e-30 105.9 0.5 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KFM24069.1 - 0.00012 22.7 7.5 0.00017 22.1 3.1 2.1 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.6 KFM24069.1 - 0.023 14.0 0.0 0.057 12.7 0.0 1.6 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily DUF1287 PF06940.11 KFM24069.1 - 0.22 11.2 0.2 0.34 10.5 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1287) Ubiquitin_2 PF14560.6 KFM24070.1 - 2e-22 79.4 0.0 3.2e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.25 KFM24070.1 - 2.1e-22 78.9 1.6 2.4e-22 78.7 0.9 1.5 2 0 0 2 2 2 1 CAP-Gly domain ubiquitin PF00240.23 KFM24070.1 - 0.00035 20.3 0.0 0.0018 18.0 0.0 2.2 2 1 0 2 2 2 1 Ubiquitin family FERM_f0 PF16511.5 KFM24070.1 - 0.064 13.6 0.0 5.4 7.4 0.0 2.3 1 1 1 2 2 2 0 N-terminal or F0 domain of Talin-head FERM TPR_1 PF00515.28 KFM24072.1 - 9.5e-15 53.7 5.5 0.00056 19.6 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFM24072.1 - 2.1e-14 52.4 12.4 3.2e-05 23.7 0.2 4.0 4 0 0 4 4 3 3 Tetratricopeptide repeat Amidase PF01425.21 KFM24072.1 - 6.3e-13 48.5 1.5 1.2e-07 31.1 2.2 2.1 2 0 0 2 2 2 2 Amidase TPR_11 PF13414.6 KFM24072.1 - 1.5e-12 47.0 1.9 4.1e-10 39.2 2.0 2.7 2 0 0 2 2 2 1 TPR repeat TPR_8 PF13181.6 KFM24072.1 - 6.5e-10 38.4 3.1 0.01 15.9 0.3 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFM24072.1 - 4.4e-08 33.7 6.5 4.4e-08 33.7 6.5 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFM24072.1 - 1.3e-06 28.4 1.3 6.8e-06 26.1 0.6 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFM24072.1 - 1.5e-05 25.0 13.3 0.002 18.2 1.3 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFM24072.1 - 1.6e-05 25.1 2.6 1.6e-05 25.1 2.6 3.9 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFM24072.1 - 3.6e-05 23.5 5.0 2 8.6 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFM24072.1 - 0.00028 21.3 10.7 0.0013 19.2 1.9 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFM24072.1 - 0.00073 19.3 1.8 0.00073 19.3 1.8 3.8 3 1 1 4 4 3 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KFM24072.1 - 0.0044 17.5 0.6 0.42 11.1 0.1 2.5 1 1 1 2 2 2 1 Alkyl sulfatase dimerisation Fis1_TPR_C PF14853.6 KFM24072.1 - 0.0065 16.5 1.6 1.6 8.8 0.0 3.5 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat CwsA PF10814.8 KFM24072.1 - 0.05 13.8 0.2 0.05 13.8 0.2 1.9 2 0 0 2 2 1 0 Cell wall synthesis protein CwsA TPR_14 PF13428.6 KFM24072.1 - 0.056 14.3 27.3 0.17 12.8 1.2 6.1 5 2 1 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFM24072.1 - 0.17 12.6 1.7 2.6 8.9 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat RibD_C PF01872.17 KFM24074.1 - 1.8e-37 129.2 0.0 9.2e-37 126.8 0.0 2.1 2 0 0 2 2 2 1 RibD C-terminal domain Aha1_N PF09229.11 KFM24074.1 - 2e-35 122.0 0.0 3.1e-35 121.3 0.0 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 KFM24074.1 - 1.1e-15 58.0 0.0 2.2e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein IBN_N PF03810.19 KFM24074.1 - 2e-11 43.6 0.0 4.3e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF1768 PF08719.11 KFM24074.1 - 1.8e-07 31.5 0.0 3.3e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) HEAT PF02985.22 KFM24074.1 - 0.19 12.1 5.4 27 5.4 0.1 4.7 3 0 0 3 3 3 0 HEAT repeat Chloroa_b-bind PF00504.21 KFM24075.1 - 6e-44 150.4 0.0 1.3e-43 149.3 0.0 1.6 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Rad21_Rec8_N PF04825.13 KFM24075.1 - 3.1e-29 101.4 0.0 5.5e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KFM24075.1 - 1.1e-10 40.6 0.0 2.4e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein DNA_pol_D_N PF18018.1 KFM24076.1 - 1.3e-36 125.5 0.0 2e-36 125.0 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DNA_pol_E_B PF04042.16 KFM24076.1 - 1.9e-36 125.4 0.0 2.8e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B TPR_2 PF07719.17 KFM24077.1 - 1.9e-06 27.6 6.0 0.023 14.8 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFM24077.1 - 1.5e-05 25.0 0.8 0.0094 16.3 0.6 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFM24077.1 - 0.0013 18.5 6.3 0.72 9.8 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFM24077.1 - 0.0061 16.2 3.0 0.053 13.2 1.6 2.3 1 1 1 2 2 2 1 TPR repeat TPR_19 PF14559.6 KFM24077.1 - 0.034 14.7 0.7 0.065 13.7 0.7 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFM24077.1 - 0.036 14.3 3.0 0.29 11.4 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TSSC4 PF15264.6 KFM24077.1 - 0.037 14.3 0.1 0.14 12.4 0.0 1.9 2 0 0 2 2 2 0 Tumour suppressing sub-chromosomal transferable candidate 4 TPR_14 PF13428.6 KFM24077.1 - 0.058 14.2 0.6 16 6.6 0.1 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFM24077.1 - 0.19 12.4 4.5 0.17 12.5 2.3 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFM24077.1 - 0.28 11.1 3.2 0.14 12.0 0.7 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.25 KFM24078.1 - 1e-49 169.3 0.0 4e-33 114.9 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFM24078.1 - 1.5e-23 83.5 0.0 1.8e-17 63.5 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KFM24078.1 - 0.00013 22.0 0.2 0.00075 19.5 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KFM24078.1 - 0.0021 17.4 0.3 0.17 11.2 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 KFM24078.1 - 0.054 12.4 0.0 0.073 12.0 0.0 1.2 1 1 0 1 1 1 0 Haspin like kinase domain RWD PF05773.22 KFM24079.1 - 4.4e-16 59.2 0.0 7.2e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 KFM24079.1 - 1.2e-08 35.3 0.2 2.6e-08 34.2 0.2 1.6 1 0 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 TF_Zn_Ribbon PF08271.12 KFM24080.1 - 2.1e-16 59.2 1.6 3.4e-16 58.5 1.6 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding zf-ribbon_3 PF13248.6 KFM24080.1 - 0.0015 17.9 3.4 0.031 13.7 3.4 2.3 1 1 0 1 1 1 1 zinc-ribbon domain Ribosomal_S27e PF01667.17 KFM24080.1 - 0.0021 17.7 0.3 0.0034 17.0 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S27 zf-RRN7 PF11781.8 KFM24080.1 - 0.0035 17.0 0.8 0.0071 16.0 0.8 1.6 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Lar_restr_allev PF14354.6 KFM24080.1 - 0.01 16.2 0.4 0.024 15.0 0.4 1.5 1 0 0 1 1 1 0 Restriction alleviation protein Lar Prim_Zn_Ribbon PF08273.12 KFM24080.1 - 0.025 14.9 0.7 0.057 13.7 0.7 1.6 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase TFIIB PF00382.19 KFM24080.1 - 0.035 14.1 0.0 0.074 13.1 0.0 1.5 1 0 0 1 1 1 0 Transcription factor TFIIB repeat DUF2318 PF10080.9 KFM24080.1 - 0.069 13.3 0.3 0.12 12.5 0.3 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) OrfB_Zn_ribbon PF07282.11 KFM24080.1 - 0.07 13.1 0.7 0.14 12.1 0.7 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Zn_Tnp_IS91 PF14319.6 KFM24080.1 - 0.094 12.8 0.3 0.18 11.8 0.3 1.4 1 0 0 1 1 1 0 Transposase zinc-binding domain HTH_6 PF01418.17 KFM24080.1 - 0.18 11.8 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family Zn-ribbon_8 PF09723.10 KFM24080.1 - 0.42 10.8 2.8 7.5 6.8 0.6 2.4 1 1 0 2 2 2 0 Zinc ribbon domain PP2C PF00481.21 KFM24081.1 - 7.8e-22 78.1 0.0 8.1e-17 61.7 0.0 2.1 1 1 1 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 KFM24081.1 - 8.4e-07 29.1 0.0 0.00013 21.9 0.0 2.6 2 1 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) FAD_binding_2 PF00890.24 KFM24082.1 - 2.9e-118 395.6 9.0 3.9e-118 395.1 9.0 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KFM24082.1 - 6.8e-44 149.0 0.7 9.9e-44 148.4 0.7 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.17 KFM24082.1 - 0.0076 15.5 0.9 3.1 7.0 0.1 2.4 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 KFM24082.1 - 0.017 14.4 1.2 0.023 13.9 0.2 1.7 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 KFM24082.1 - 0.022 14.0 0.2 0.08 12.2 0.1 2.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KFM24082.1 - 0.042 12.9 1.3 0.14 11.2 1.3 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Spore_GerAC PF05504.11 KFM24083.1 - 0.012 15.9 0.2 0.013 15.7 0.2 1.1 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal DUF2515 PF10720.9 KFM24084.1 - 0.0022 17.2 0.1 0.0025 17.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2515) RPN13_C PF16550.5 KFM24084.1 - 0.015 15.5 0.8 0.021 15.0 0.8 1.4 1 1 0 1 1 1 0 UCH-binding domain DUF1627 PF07789.12 KFM24084.1 - 0.025 14.3 0.3 0.036 13.7 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1627) Hemerythrin PF01814.23 KFM24084.1 - 0.07 13.8 2.0 0.067 13.8 0.5 1.7 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain Med26 PF08711.11 KFM24084.1 - 0.08 13.0 0.9 0.33 11.0 0.0 2.4 2 2 0 2 2 2 0 TFIIS helical bundle-like domain Snf7 PF03357.21 KFM24085.1 - 1.2e-21 77.1 11.3 1.4e-21 76.9 11.3 1.0 1 0 0 1 1 1 1 Snf7 SET PF00856.28 KFM24086.1 - 8.9e-16 58.7 0.2 2e-11 44.6 0.0 2.7 2 1 1 3 3 3 2 SET domain AWS PF17907.1 KFM24086.1 - 3.6e-11 42.9 2.4 3.6e-11 42.9 2.4 2.6 3 0 0 3 3 3 1 AWS domain PWWP PF00855.17 KFM24086.1 - 0.022 15.2 0.1 0.035 14.5 0.1 1.3 1 0 0 1 1 1 0 PWWP domain DNA_pol_B_exo1 PF03104.19 KFM24087.1 - 2e-17 63.4 0.0 6e-05 22.3 0.0 3.1 3 0 0 3 3 3 3 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 KFM24088.1 - 2.6e-86 290.2 0.0 3e-86 290.0 0.0 1.0 1 0 0 1 1 1 1 DNA polymerase family B zf-C4pol PF14260.6 KFM24088.1 - 1.2e-07 32.1 7.3 1.5e-06 28.6 0.9 2.7 3 0 0 3 3 3 2 C4-type zinc-finger of DNA polymerase delta AHJR-like PF18743.1 KFM24088.1 - 0.18 11.3 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 REase_AHJR-like AAA_2 PF07724.14 KFM24089.1 - 2.7e-26 92.7 0.0 2e-24 86.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 KFM24089.1 - 6.7e-15 55.7 0.0 1.2e-06 28.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Clp_N PF02861.20 KFM24089.1 - 2.1e-10 40.5 0.5 0.0012 18.9 0.0 3.3 3 0 0 3 3 2 2 Clp amino terminal domain, pathogenicity island component AAA_5 PF07728.14 KFM24089.1 - 4.1e-10 39.8 3.4 9.7e-06 25.6 0.2 3.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFM24089.1 - 1.4e-08 35.3 15.8 1.8e-06 28.5 1.0 5.1 2 2 2 4 4 4 2 AAA ATPase domain IstB_IS21 PF01695.17 KFM24089.1 - 2.1e-05 24.3 0.0 0.073 12.8 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_22 PF13401.6 KFM24089.1 - 0.00025 21.3 3.0 0.88 9.8 0.2 4.2 2 2 1 3 3 3 1 AAA domain NACHT PF05729.12 KFM24089.1 - 0.0025 17.8 2.4 0.017 15.1 0.1 2.8 3 0 0 3 3 3 1 NACHT domain Mg_chelatase PF01078.21 KFM24089.1 - 0.0028 17.1 1.4 0.08 12.3 0.1 3.0 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KFM24089.1 - 0.0037 16.9 0.5 0.081 12.5 0.1 3.2 3 0 0 3 3 3 1 AAA domain TniB PF05621.11 KFM24089.1 - 0.0041 16.6 0.0 0.41 10.0 0.0 3.0 3 0 0 3 3 3 1 Bacterial TniB protein AAA_30 PF13604.6 KFM24089.1 - 0.01 15.6 0.7 0.21 11.3 0.1 3.3 3 0 0 3 3 3 0 AAA domain RuvB_N PF05496.12 KFM24089.1 - 0.011 15.5 0.2 5.7 6.7 0.0 3.5 3 1 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KFM24089.1 - 0.019 14.5 0.0 0.96 8.9 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 KFM24089.1 - 0.029 14.4 0.2 0.19 11.7 0.0 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KFM24089.1 - 0.032 14.6 0.2 14 6.1 0.1 2.4 2 0 0 2 2 2 0 RNA helicase ATPase_2 PF01637.18 KFM24089.1 - 0.037 13.9 0.1 0.16 11.8 0.0 2.0 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 KFM24089.1 - 0.042 14.4 0.8 2.6 8.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KFM24089.1 - 0.056 12.7 1.0 1 8.6 0.0 3.1 4 0 0 4 4 4 0 Zeta toxin RsgA_GTPase PF03193.16 KFM24089.1 - 0.07 13.0 0.0 0.35 10.8 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA_33 PF13671.6 KFM24089.1 - 0.073 13.2 6.7 0.74 10.0 0.0 3.9 4 0 0 4 4 4 0 AAA domain ABC_tran PF00005.27 KFM24089.1 - 0.2 12.2 0.3 19 5.8 0.1 2.4 2 0 0 2 2 2 0 ABC transporter ClpB_D2-small PF10431.9 KFM24091.1 - 1.6e-08 34.4 0.1 1.7e-06 27.9 0.1 2.1 2 0 0 2 2 2 2 C-terminal, D2-small domain, of ClpB protein EIF_2_alpha PF07541.12 KFM24092.1 - 1.4e-38 131.6 0.0 7.9e-38 129.1 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit PsbW PF07123.12 KFM24092.1 - 1.8e-20 73.3 0.3 6.1e-20 71.6 0.1 2.0 1 1 1 2 2 2 1 Photosystem II reaction centre W protein (PsbW) S1 PF00575.23 KFM24092.1 - 4.3e-16 59.0 0.3 8.1e-16 58.1 0.3 1.5 1 0 0 1 1 1 1 S1 RNA binding domain HAD PF12710.7 KFM24093.1 - 3.7e-07 30.7 0.1 6.3e-07 30.0 0.1 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFM24093.1 - 5.8e-07 30.0 0.6 7.4e-06 26.4 0.6 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KFM24093.1 - 4.5e-06 26.9 0.0 0.00046 20.3 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFM24093.1 - 1e-05 25.5 0.2 2.2e-05 24.4 0.2 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Stathmin PF00836.19 KFM24094.1 - 0.11 12.4 0.0 0.11 12.4 0.0 2.3 3 0 0 3 3 3 0 Stathmin family CK_II_beta PF01214.18 KFM24094.1 - 0.2 11.4 0.1 0.32 10.8 0.1 1.2 1 0 0 1 1 1 0 Casein kinase II regulatory subunit TPR_MLP1_2 PF07926.12 KFM24094.1 - 0.25 11.4 9.4 0.2 11.7 4.0 2.7 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Lebercilin PF15619.6 KFM24094.1 - 1.3 8.6 8.9 9.1 5.9 5.1 2.7 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF883 PF05957.13 KFM24094.1 - 2.4 8.8 11.9 0.41 11.3 2.9 3.0 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF883) XRN_M PF17846.1 KFM24095.1 - 3.7e-135 451.3 0.0 3.3e-95 319.7 0.0 3.4 3 1 0 3 3 3 2 Xrn1 helical domain XRN_N PF03159.18 KFM24095.1 - 8.7e-100 333.1 0.0 1.9e-99 332.0 0.0 1.5 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus CBFD_NFYB_HMF PF00808.23 KFM24096.1 - 5.7e-25 87.4 0.2 7.5e-25 87.0 0.2 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFM24096.1 - 1.5e-05 25.3 0.0 2e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KFM24096.1 - 0.0039 17.3 0.0 0.0055 16.8 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 KFM24096.1 - 0.028 14.4 0.0 0.12 12.4 0.0 1.9 1 1 1 2 2 2 0 Bromodomain associated PGF-CTERM PF18204.1 KFM24097.1 - 0.0083 16.1 0.3 0.021 14.8 0.3 1.7 1 0 0 1 1 1 1 PGF-CTERM motif Cript PF10235.9 KFM24099.1 - 1.1e-29 102.8 8.1 1.1e-29 102.8 8.1 1.5 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT zinc_ribbon_2 PF13240.6 KFM24099.1 - 0.00031 20.3 9.3 1.8 8.4 3.7 3.5 3 0 0 3 3 3 3 zinc-ribbon domain Gin PF10764.9 KFM24099.1 - 0.013 15.5 6.9 0.49 10.4 0.5 2.8 2 1 0 2 2 2 0 Inhibitor of sigma-G Gin LIM PF00412.22 KFM24099.1 - 0.051 13.8 10.6 2.5 8.4 1.3 3.3 3 1 0 3 3 3 0 LIM domain zinc_ribbon_15 PF17032.5 KFM24099.1 - 0.073 13.8 10.6 0.15 12.8 7.7 2.4 2 1 0 2 2 2 0 zinc-ribbon family DUF1272 PF06906.11 KFM24099.1 - 0.33 11.1 9.9 0.63 10.2 3.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) DZR PF12773.7 KFM24099.1 - 0.36 10.9 13.2 2.4 8.2 6.1 2.7 1 1 1 2 2 2 0 Double zinc ribbon DUF2039 PF10217.9 KFM24099.1 - 0.56 10.6 16.7 7.7 6.9 16.7 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Zn_ribbon_17 PF17120.5 KFM24099.1 - 1.7 8.4 9.1 1.4 8.6 2.0 2.7 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 KFM24099.1 - 2.2 8.2 14.0 6.1 6.8 5.5 3.0 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF4428 PF14471.6 KFM24099.1 - 8.4 6.4 14.3 2.3 8.2 0.6 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4428) DUF842 PF05811.13 KFM24100.1 - 1e-31 109.3 15.8 1.2e-31 109.1 15.8 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) Vicilin_N PF04702.12 KFM24100.1 - 3.9e-05 23.5 15.3 0.0054 16.6 16.5 2.1 1 1 1 2 2 2 2 Vicilin N terminal region CLZ PF16526.5 KFM24100.1 - 0.049 14.0 0.7 12 6.3 0.0 3.0 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Sod_Fe_N PF00081.22 KFM24101.1 - 9.2e-31 106.2 0.2 1.1e-30 105.9 0.2 1.1 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.18 KFM24102.1 - 2.8e-42 143.0 0.1 3.3e-42 142.8 0.1 1.1 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Pro_Al_protease PF02983.14 KFM24102.1 - 0.088 12.9 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Alpha-lytic protease prodomain OSCP PF00213.18 KFM24104.1 - 1.6e-44 152.1 0.9 1.8e-44 151.9 0.9 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit DUF3593 PF12159.8 KFM24105.1 - 1.3e-13 50.8 0.0 1.7e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3593) EMC3_TMCO1 PF01956.16 KFM24105.1 - 0.11 12.3 0.6 0.11 12.2 0.6 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Spc24 PF08286.11 KFM24107.1 - 1.2e-08 35.1 0.1 3.7e-08 33.6 0.0 1.7 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 CALCOCO1 PF07888.11 KFM24107.1 - 0.00068 18.6 7.1 0.00082 18.4 7.1 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like ALIX_LYPXL_bnd PF13949.6 KFM24107.1 - 0.0073 15.6 3.2 0.0091 15.3 3.2 1.1 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Spc7 PF08317.11 KFM24107.1 - 0.0077 15.2 3.7 0.0095 14.8 3.7 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Phlebovirus_NSM PF07246.11 KFM24107.1 - 0.011 15.2 1.3 0.014 14.8 1.3 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF16 PF01519.16 KFM24107.1 - 0.028 14.9 2.8 0.12 12.9 2.8 2.0 1 1 0 1 1 1 0 Protein of unknown function DUF16 PI3K_P85_iSH2 PF16454.5 KFM24107.1 - 0.031 13.9 0.4 1.7 8.2 0.4 2.2 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4806 PF16064.5 KFM24107.1 - 0.057 13.7 0.5 6.1 7.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4806) PspA_IM30 PF04012.12 KFM24107.1 - 0.06 12.9 7.4 0.079 12.5 7.4 1.1 1 0 0 1 1 1 0 PspA/IM30 family GvpL_GvpF PF06386.11 KFM24107.1 - 0.069 13.1 4.0 0.094 12.6 4.0 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DsrC PF04358.13 KFM24107.1 - 0.072 13.6 0.0 0.19 12.2 0.0 1.8 1 1 0 1 1 1 0 DsrC like protein AAA_13 PF13166.6 KFM24107.1 - 0.086 11.5 1.8 0.11 11.2 1.8 1.1 1 0 0 1 1 1 0 AAA domain HNOBA PF07701.14 KFM24107.1 - 0.087 12.2 1.7 0.11 11.9 1.4 1.3 1 1 0 1 1 1 0 Heme NO binding associated Seryl_tRNA_N PF02403.22 KFM24107.1 - 0.094 12.9 3.8 0.091 13.0 2.0 1.7 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TMF_DNA_bd PF12329.8 KFM24107.1 - 0.098 12.7 4.6 0.22 11.5 1.8 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Mod_r PF07200.13 KFM24107.1 - 0.12 12.5 3.4 0.19 11.9 3.4 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein FlaC_arch PF05377.11 KFM24107.1 - 0.14 12.5 2.3 7.4 7.1 0.1 3.1 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) MLTR_LBD PF17765.1 KFM24107.1 - 0.34 11.0 4.1 2.2 8.4 0.8 2.3 1 1 0 2 2 2 0 MmyB-like transcription regulator ligand binding domain IFT20 PF14931.6 KFM24107.1 - 0.49 10.6 3.6 1 9.6 3.5 1.5 1 1 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 PKcGMP_CC PF16808.5 KFM24107.1 - 0.6 10.0 3.9 1 9.2 0.1 2.8 3 0 0 3 3 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SlyX PF04102.12 KFM24107.1 - 0.71 10.5 4.9 0.58 10.8 1.2 2.4 2 0 0 2 2 2 0 SlyX APG6_N PF17675.1 KFM24107.1 - 1.1 9.8 8.5 3.1 8.3 8.5 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region Cortex-I_coil PF09304.10 KFM24107.1 - 2.3 8.4 7.7 5.5 7.3 2.2 2.2 1 1 1 2 2 2 0 Cortexillin I, coiled coil ZapB PF06005.12 KFM24107.1 - 2.9 8.4 8.6 0.46 11.0 2.5 2.2 1 1 1 2 2 2 0 Cell division protein ZapB WRKY PF03106.15 KFM24109.1 - 2.4e-35 120.5 13.6 1.4e-17 63.7 4.4 2.3 2 0 0 2 2 2 2 WRKY DNA -binding domain zf-CCCH PF00642.24 KFM24110.1 - 3.1e-09 36.5 2.5 3.1e-09 36.5 2.5 2.3 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_5 PF14634.6 KFM24110.1 - 4.8e-08 32.8 8.2 7.9e-08 32.1 8.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFM24110.1 - 4.9e-07 29.5 4.7 1e-06 28.5 4.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf_CCCH_4 PF18345.1 KFM24110.1 - 2.3e-05 24.3 4.4 2.3e-05 24.3 4.4 2.0 2 0 0 2 2 2 1 Zinc finger domain zf-C3HC4_2 PF13923.6 KFM24110.1 - 2.7e-05 23.9 8.6 6.3e-05 22.7 8.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFM24110.1 - 3.4e-05 23.8 6.5 6.8e-05 22.8 6.5 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFM24110.1 - 3.6e-05 24.0 7.7 7.2e-05 23.0 7.7 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KFM24110.1 - 0.00044 20.0 5.8 0.00076 19.3 5.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Rubredoxin_2 PF18073.1 KFM24110.1 - 0.0038 16.9 3.6 0.0038 16.9 3.6 2.0 2 0 0 2 2 2 1 Rubredoxin metal binding domain zf-CCCH_4 PF18044.1 KFM24110.1 - 0.0044 16.8 2.6 0.0044 16.8 2.6 2.1 2 0 0 2 2 1 1 CCCH-type zinc finger zinc-ribbons_6 PF07191.12 KFM24110.1 - 0.0045 16.9 3.5 0.01 15.8 3.5 1.6 1 0 0 1 1 1 1 zinc-ribbons zf-C3HC4 PF00097.25 KFM24110.1 - 0.0048 16.7 7.8 0.011 15.6 7.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 KFM24110.1 - 0.0056 16.8 3.0 0.0056 16.8 3.0 1.7 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 KFM24110.1 - 0.017 15.3 7.7 0.14 12.3 8.0 2.3 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-P11 PF03854.14 KFM24110.1 - 0.052 13.2 1.9 0.1 12.3 1.9 1.4 1 0 0 1 1 1 0 P-11 zinc finger Cript PF10235.9 KFM24110.1 - 0.09 13.4 1.1 0.25 11.9 1.1 1.8 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT zf-CCCH_2 PF14608.6 KFM24110.1 - 0.092 13.3 1.9 0.17 12.4 1.9 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-rbx1 PF12678.7 KFM24110.1 - 0.14 12.5 5.9 0.27 11.5 5.9 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 KFM24110.1 - 0.18 11.6 6.4 0.11 12.3 3.1 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 KFM24110.1 - 0.47 10.5 3.2 1.2 9.3 3.2 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.7 KFM24110.1 - 0.49 10.5 7.7 2.6 8.1 7.9 1.8 1 1 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 KFM24110.1 - 0.55 10.4 7.6 0.2 11.8 3.6 2.2 1 1 1 2 2 2 0 Zinc ribbon domain Protamine_P2 PF00841.19 KFM24110.1 - 1.3 9.6 5.2 0.3 11.6 1.0 2.2 2 0 0 2 2 1 0 Sperm histone P2 SCO1-SenC PF02630.14 KFM24111.1 - 1.4e-42 144.8 0.0 3e-42 143.7 0.0 1.5 1 1 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 KFM24111.1 - 0.00015 21.6 0.0 0.00029 20.7 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KFM24111.1 - 0.0024 18.1 0.0 0.0045 17.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like SIS PF01380.22 KFM24111.1 - 0.083 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 SIS domain DnaJ PF00226.31 KFM24112.1 - 3.8e-18 65.4 0.0 6.9e-18 64.5 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain mRNA_cap_enzyme PF01331.19 KFM24114.1 - 5.5e-51 173.2 0.0 7.8e-51 172.7 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 KFM24114.1 - 8e-16 58.6 0.0 3.1e-15 56.7 0.0 2.0 1 1 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DSPc PF00782.20 KFM24114.1 - 5.2e-09 36.0 0.0 1.5e-08 34.5 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain DNA_ligase_A_M PF01068.21 KFM24114.1 - 1.8e-06 27.7 0.0 0.00043 20.0 0.0 2.8 1 1 0 1 1 1 1 ATP dependent DNA ligase domain Y_phosphatase PF00102.27 KFM24114.1 - 0.0025 17.4 0.0 0.0039 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KFM24114.1 - 0.011 15.9 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KFM24114.1 - 0.046 13.7 0.0 0.083 12.9 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family RRM_1 PF00076.22 KFM24115.1 - 1.9e-56 187.7 0.0 2.1e-15 56.3 0.0 5.2 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFM24115.1 - 0.00077 19.1 0.0 0.017 14.7 0.0 2.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFM24115.1 - 0.016 15.3 0.0 0.21 11.8 0.0 2.8 3 0 0 3 3 3 0 RNA recognition motif Limkain-b1 PF11608.8 KFM24115.1 - 0.16 12.1 1.3 8.9 6.5 0.0 3.6 5 0 0 5 5 5 0 Limkain b1 PHM7_cyt PF14703.6 KFM24115.1 - 0.17 12.1 7.8 1.6 8.9 0.2 5.4 6 2 2 8 8 8 0 Cytosolic domain of 10TM putative phosphate transporter Whirly PF08536.11 KFM24116.1 - 5.1e-39 133.2 0.0 6.4e-39 132.9 0.0 1.1 1 0 0 1 1 1 1 Whirly transcription factor NAD_binding_10 PF13460.6 KFM24117.1 - 1.9e-06 27.9 1.8 4.1e-06 26.8 1.8 1.6 1 0 0 1 1 1 1 NAD(P)H-binding DUF5330 PF17264.2 KFM24117.1 - 0.013 15.5 0.1 0.029 14.4 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5330) Ribosomal_60s PF00428.19 KFM24117.1 - 3.1 8.5 6.9 14 6.3 3.7 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein Yippee-Mis18 PF03226.14 KFM24118.1 - 6.5e-11 42.4 0.0 6.6e-11 42.3 0.0 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly AAA_16 PF13191.6 KFM24119.1 - 0.025 15.0 0.0 0.039 14.4 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 KFM24119.1 - 0.027 14.1 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KFM24119.1 - 0.13 11.6 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 KaiC AAA_11 PF13086.6 KFM24119.1 - 0.15 11.8 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain SWIRM-assoc_2 PF16496.5 KFM24120.1 - 3.2e-30 105.4 0.0 4.3e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 SWIRM-associated domain at the N-terminal SWIRM PF04433.17 KFM24120.1 - 1.8e-18 66.6 0.0 5.4e-18 65.1 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 KFM24120.1 - 5e-11 42.4 6.2 5e-11 42.4 6.2 2.0 2 0 0 2 2 2 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 KFM24120.1 - 5.3e-06 26.5 0.0 2.3e-05 24.5 0.0 2.1 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFM24120.1 - 0.027 14.7 0.0 0.078 13.2 0.0 1.7 2 0 0 2 2 2 0 Myb-like DNA-binding domain ZZ PF00569.17 KFM24120.1 - 0.027 14.3 1.1 0.048 13.5 1.1 1.4 1 0 0 1 1 1 0 Zinc finger, ZZ type DUF2659 PF10858.8 KFM24120.1 - 0.29 10.8 0.0 0.47 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2659) DAGAT PF03982.13 KFM24121.1 - 4e-27 94.9 0.0 6.5e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol acyltransferase PALP PF00291.25 KFM24122.1 - 2.7e-46 158.3 12.9 3.3e-30 105.5 4.2 2.0 1 1 1 2 2 2 2 Pyridoxal-phosphate dependent enzyme Ctf8 PF09696.10 KFM24123.1 - 1.4e-07 32.0 0.1 3.4e-05 24.2 0.0 2.8 1 1 1 2 2 2 1 Ctf8 RNA_pol_Rpb1_1 PF04997.12 KFM24124.1 - 4.4e-97 325.2 0.0 6.3e-97 324.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KFM24124.1 - 1.5e-96 323.0 0.0 5e-96 321.2 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KFM24124.1 - 3.5e-68 229.0 0.1 1.1e-67 227.4 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 KFM24124.1 - 2e-54 184.4 0.0 3.2e-54 183.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 KFM24124.1 - 4.9e-49 166.3 0.0 8.8e-49 165.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 KFM24124.1 - 1.2e-45 154.8 0.0 3.2e-45 153.4 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 KFM24124.1 - 3e-38 130.1 0.5 5.8e-38 129.1 0.5 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 adh_short_C2 PF13561.6 KFM24125.1 - 4e-56 190.2 0.8 4.7e-56 190.0 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFM24125.1 - 3e-47 160.6 0.4 3.7e-47 160.3 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFM24125.1 - 4.2e-11 43.1 0.3 5.8e-11 42.6 0.3 1.2 1 0 0 1 1 1 1 KR domain Pkinase PF00069.25 KFM24126.1 - 1e-15 57.8 0.0 1.2e-07 31.4 0.0 3.1 1 1 2 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFM24126.1 - 1.2e-15 57.5 0.0 8.1e-06 25.3 0.0 3.1 1 1 2 3 3 3 3 Protein tyrosine kinase TRAF_BIRC3_bd PF16673.5 KFM24126.1 - 0.0023 17.7 0.4 0.0046 16.7 0.4 1.5 1 0 0 1 1 1 1 TNF receptor-associated factor BIRC3 binding domain ZapB PF06005.12 KFM24126.1 - 0.06 13.8 0.8 0.099 13.1 0.8 1.3 1 0 0 1 1 1 0 Cell division protein ZapB DUF1664 PF07889.12 KFM24126.1 - 0.074 13.1 0.1 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Tropomyosin PF00261.20 KFM24126.1 - 0.12 11.7 0.8 0.19 11.1 0.8 1.2 1 0 0 1 1 1 0 Tropomyosin HOOK PF05622.12 KFM24126.1 - 0.16 10.1 0.1 0.21 9.7 0.1 1.0 1 0 0 1 1 1 0 HOOK protein NIF PF03031.18 KFM24127.1 - 9.6e-23 80.7 0.0 2.3e-22 79.4 0.1 1.6 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase TBK1_ULD PF18396.1 KFM24127.1 - 0.073 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain RETICULATA-like PF11891.8 KFM24128.1 - 3.7e-53 180.0 0.0 7e-53 179.1 0.0 1.5 1 0 0 1 1 1 1 Protein RETICULATA-related BRO1 PF03097.18 KFM24128.1 - 1.2e-07 30.9 8.0 1.7e-07 30.4 8.0 1.1 1 0 0 1 1 1 1 BRO1-like domain 2OG-FeII_Oxy_2 PF13532.6 KFM24129.1 - 3.7e-18 66.4 0.0 5.6e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Methyltransf_11 PF08241.12 KFM24129.1 - 4.2e-10 40.2 0.4 1.7e-07 31.8 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM24129.1 - 1.4e-08 35.4 1.6 2.3e-06 28.2 0.1 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM24129.1 - 0.00018 21.3 0.0 0.024 14.5 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM24129.1 - 0.00023 21.1 0.0 0.028 14.3 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain RRM_4 PF10598.9 KFM24129.1 - 0.0018 18.6 0.0 0.29 11.5 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif of the spliceosomal PrP8 Methyltransf_12 PF08242.12 KFM24129.1 - 0.0042 17.8 0.2 0.074 13.8 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.12 KFM24129.1 - 0.0068 16.0 0.0 3.5 7.2 0.0 2.4 2 0 0 2 2 2 2 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.11 KFM24129.1 - 0.0085 15.0 0.0 2 7.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1698) GRAM PF02893.20 KFM24130.1 - 0.22 11.4 0.0 0.28 11.1 0.0 1.2 1 0 0 1 1 1 0 GRAM domain Choline_transpo PF04515.12 KFM24131.1 - 1.8e-55 188.4 3.9 1.8e-55 188.4 3.9 1.4 2 0 0 2 2 2 1 Plasma-membrane choline transporter URO-D PF01208.17 KFM24132.1 - 9.1e-106 353.9 0.0 1.2e-105 353.5 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) WD40 PF00400.32 KFM24133.1 - 1.9e-21 76.0 23.1 3.9e-05 24.3 0.1 7.0 8 0 0 8 8 8 5 WD domain, G-beta repeat Hira PF07569.11 KFM24133.1 - 1.2e-09 38.2 0.9 7.1e-08 32.5 0.7 2.3 1 1 1 2 2 2 2 TUP1-like enhancer of split ANAPC4_WD40 PF12894.7 KFM24133.1 - 4e-09 36.6 0.3 0.00084 19.6 0.2 4.4 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFM24133.1 - 0.16 10.9 0.8 1.5 7.7 0.0 2.7 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CAS_CSE1 PF03378.15 KFM24134.1 - 8e-125 416.8 0.0 1.3e-113 379.8 0.0 2.3 2 0 0 2 2 2 2 CAS/CSE protein, C-terminus Cse1 PF08506.10 KFM24134.1 - 3e-102 342.2 0.0 1.8e-101 339.6 0.0 2.0 1 1 0 1 1 1 1 Cse1 IBN_N PF03810.19 KFM24134.1 - 1.1e-14 54.1 0.0 1.5e-13 50.5 0.0 3.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KFM24134.1 - 0.024 14.7 0.1 0.29 11.2 0.0 2.7 2 0 0 2 2 2 0 Exportin 1-like protein Glyc_hyd_38C_2 PF18230.1 KFM24134.1 - 0.046 13.8 0.1 0.14 12.3 0.1 1.8 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal sub-domain PAP_fibrillin PF04755.12 KFM24135.1 - 5.4e-36 124.4 0.0 3.6e-34 118.4 0.0 2.0 1 1 0 1 1 1 1 PAP_fibrillin Vps55 PF04133.14 KFM24136.1 - 5.3e-27 94.1 4.7 5.8e-27 94.0 4.7 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 MRC1 PF09444.10 KFM24137.1 - 1.2e-06 29.2 9.5 1.2e-06 29.2 9.5 3.9 1 1 1 3 3 3 1 MRC1-like domain Spt5_N PF11942.8 KFM24137.1 - 0.0068 17.4 4.1 0.0068 17.4 4.1 3.4 3 1 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal Rhodanese PF00581.20 KFM24138.1 - 6.6e-06 26.6 0.0 0.0024 18.4 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain DUF1952 PF09189.10 KFM24138.1 - 0.06 13.2 0.1 5.1 7.0 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1952) Memo PF01875.17 KFM24139.1 - 3.1e-58 197.1 0.0 2.3e-44 151.6 0.0 2.0 1 1 1 2 2 2 2 Memo-like protein SRP19 PF01922.17 KFM24140.1 - 1.8e-23 83.3 0.0 2.4e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 SRP19 protein AAA PF00004.29 KFM24141.1 - 1.6e-38 132.1 0.0 2.8e-38 131.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 KFM24141.1 - 4.3e-18 65.5 0.1 6.9e-18 64.8 0.1 1.4 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 KFM24141.1 - 0.0003 20.5 1.4 0.0003 20.5 1.4 3.1 4 0 0 4 4 3 1 AAA+ lid domain IstB_IS21 PF01695.17 KFM24141.1 - 0.0013 18.5 0.8 0.02 14.6 0.0 2.8 3 0 0 3 3 3 1 IstB-like ATP binding protein Smr PF01713.21 KFM24141.1 - 0.0016 18.8 1.1 2.6 8.5 0.1 2.8 2 0 0 2 2 2 2 Smr domain AAA_16 PF13191.6 KFM24141.1 - 0.0021 18.5 9.7 0.0052 17.2 0.1 3.9 2 1 0 4 4 4 1 AAA ATPase domain AAA_33 PF13671.6 KFM24141.1 - 0.014 15.6 0.0 0.03 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KFM24141.1 - 0.016 14.9 0.0 0.056 13.2 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain CDC48_2 PF02933.17 KFM24141.1 - 0.02 14.7 0.1 0.05 13.4 0.1 1.6 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 AAA_5 PF07728.14 KFM24141.1 - 0.022 14.7 0.0 0.053 13.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KFM24141.1 - 0.055 13.7 0.1 0.53 10.6 0.1 2.4 2 1 1 3 3 3 0 AAA domain AAA_11 PF13086.6 KFM24141.1 - 0.066 13.0 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KFM24141.1 - 0.084 12.9 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KFM24141.1 - 0.089 12.7 0.0 12 5.8 0.0 2.3 1 1 1 2 2 2 0 NACHT domain AAA_25 PF13481.6 KFM24141.1 - 0.092 12.3 6.0 1.1 8.8 0.1 3.2 2 1 1 3 3 3 0 AAA domain Rad17 PF03215.15 KFM24141.1 - 0.25 11.3 0.0 0.39 10.6 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain tRNA-synt_1c PF00749.21 KFM24142.1 - 1.6e-84 283.5 0.0 2e-84 283.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain COG4 PF08318.12 KFM24143.1 - 1.1e-37 129.9 0.0 5.8e-20 71.7 0.0 2.3 1 1 1 2 2 2 2 COG4 transport protein DUF4404 PF14357.6 KFM24143.1 - 0.047 14.3 1.4 4.7 7.9 0.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) ATP-synt_ab PF00006.25 KFM24144.1 - 3.5e-67 226.2 0.0 4.8e-67 225.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KFM24144.1 - 1.7e-09 38.1 1.6 3.7e-09 37.0 1.6 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain PI3_PI4_kinase PF00454.27 KFM24145.1 - 2.3e-36 125.9 0.0 1.8e-17 64.0 0.0 3.3 1 1 2 3 3 3 3 Phosphatidylinositol 3- and 4-kinase XPG_N PF00752.17 KFM24145.1 - 1.9e-27 95.7 0.0 4.9e-27 94.4 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KFM24145.1 - 2.2e-26 92.0 0.0 6.6e-26 90.5 0.0 1.9 1 0 0 1 1 1 1 XPG I-region PI3Ka PF00613.20 KFM24145.1 - 7.7e-14 51.5 0.0 5e-13 48.9 0.0 2.0 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) XPG_I_2 PF12813.7 KFM24145.1 - 0.0016 18.0 0.0 0.0035 16.8 0.0 1.5 1 0 0 1 1 1 1 XPG domain containing UIM PF02809.20 KFM24145.1 - 0.052 13.5 7.0 0.2 11.6 7.0 2.1 1 0 0 1 1 1 0 Ubiquitin interaction motif 5_3_exonuc PF01367.20 KFM24145.1 - 0.098 13.3 0.0 0.3 11.7 0.0 1.8 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold Peptidase_M17_N PF02789.17 KFM24145.1 - 1.1 9.2 3.8 0.68 9.8 0.4 2.5 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain GCP_N_terminal PF17681.1 KFM24147.1 - 3.2e-36 125.5 0.0 2.1e-35 122.9 0.0 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KFM24147.1 - 1.7e-27 96.7 0.0 2.8e-27 96.0 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal Phasin_2 PF09361.10 KFM24147.1 - 0.63 10.3 3.1 1.6 9.0 3.1 1.7 1 0 0 1 1 1 0 Phasin protein TPT PF03151.16 KFM24148.1 - 4.8e-10 39.2 9.6 6.1e-10 38.9 9.6 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KFM24148.1 - 6.2e-05 22.3 8.5 8.4e-05 21.9 8.5 1.2 1 0 0 1 1 1 1 UAA transporter family ABC_tran PF00005.27 KFM24149.1 - 2e-44 151.4 0.0 1.1e-22 81.0 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KFM24149.1 - 5.3e-20 71.2 8.0 5.3e-20 71.2 8.0 2.5 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.6 KFM24149.1 - 2.6e-19 70.2 3.2 2.8e-05 24.1 0.0 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFM24149.1 - 3e-08 33.4 0.1 0.14 11.6 0.0 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KFM24149.1 - 2.7e-07 30.2 0.1 0.022 14.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KFM24149.1 - 3.5e-07 30.8 0.1 0.0063 16.9 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_28 PF13521.6 KFM24149.1 - 7.9e-07 29.5 0.1 0.0068 16.7 0.1 2.7 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KFM24149.1 - 1.5e-06 28.2 1.1 0.014 15.2 0.0 3.3 4 1 0 4 4 4 2 AAA ATPase domain AAA_23 PF13476.6 KFM24149.1 - 2e-06 28.4 8.4 0.027 15.0 0.0 3.9 4 0 0 4 4 4 2 AAA domain AAA PF00004.29 KFM24149.1 - 2.5e-06 27.9 0.0 0.069 13.6 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFM24149.1 - 5.4e-06 26.7 0.5 0.083 13.2 0.1 3.0 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KFM24149.1 - 1.6e-05 24.8 0.0 0.073 13.0 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 KFM24149.1 - 1.7e-05 25.4 0.3 0.17 12.4 0.0 3.8 5 0 0 5 5 2 2 AAA domain AAA_33 PF13671.6 KFM24149.1 - 2.5e-05 24.5 0.1 0.55 10.4 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_14 PF13173.6 KFM24149.1 - 3.4e-05 23.9 0.0 0.73 9.9 0.0 3.6 4 1 0 4 4 3 2 AAA domain Rad17 PF03215.15 KFM24149.1 - 5.2e-05 23.2 0.0 0.49 10.3 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain RNA_helicase PF00910.22 KFM24149.1 - 6.2e-05 23.3 0.0 0.56 10.6 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_24 PF13479.6 KFM24149.1 - 7.1e-05 22.6 0.1 0.97 9.1 0.0 3.2 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 KFM24149.1 - 7.1e-05 22.9 0.0 0.12 12.5 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATPase_2 PF01637.18 KFM24149.1 - 8.2e-05 22.6 0.2 0.14 12.1 0.0 2.8 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_5 PF07728.14 KFM24149.1 - 0.00015 21.7 0.1 0.83 9.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) NACHT PF05729.12 KFM24149.1 - 0.00079 19.4 2.0 0.75 9.7 0.1 3.1 3 0 0 3 3 2 2 NACHT domain AAA_27 PF13514.6 KFM24149.1 - 0.00088 18.9 2.9 0.54 9.8 0.0 3.3 2 1 1 3 3 3 1 AAA domain AAA_25 PF13481.6 KFM24149.1 - 0.0026 17.4 0.5 2.1 7.9 0.0 3.8 4 0 0 4 4 4 1 AAA domain PduV-EutP PF10662.9 KFM24149.1 - 0.0043 16.8 0.0 3.7 7.3 0.0 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 KFM24149.1 - 0.011 14.9 0.0 4.7 6.3 0.0 2.6 3 0 0 3 3 3 0 G-protein alpha subunit AAA_7 PF12775.7 KFM24149.1 - 0.012 15.2 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Cytidylate_kin PF02224.18 KFM24149.1 - 0.013 15.2 0.4 3.9 7.1 0.0 2.6 3 0 0 3 3 2 0 Cytidylate kinase DUF815 PF05673.13 KFM24149.1 - 0.013 14.6 0.1 8.5 5.5 0.0 3.1 3 1 0 3 3 2 0 Protein of unknown function (DUF815) NB-ARC PF00931.22 KFM24149.1 - 0.015 14.5 0.0 1.4 8.0 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_17 PF13207.6 KFM24149.1 - 0.02 15.3 0.1 3.9 7.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KFM24149.1 - 0.027 14.2 2.2 3.5 7.3 0.0 3.5 3 2 0 3 3 3 0 AAA domain DUF2813 PF11398.8 KFM24149.1 - 0.037 13.3 0.2 8.2 5.6 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) FeoB_N PF02421.18 KFM24149.1 - 0.048 13.2 0.0 1.8 8.1 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B dNK PF01712.19 KFM24149.1 - 0.049 13.5 0.2 5.2 6.9 0.0 3.0 3 0 0 3 3 3 0 Deoxynucleoside kinase IstB_IS21 PF01695.17 KFM24149.1 - 0.052 13.3 0.0 4.9 6.9 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein Methyltransf_12 PF08242.12 KFM24149.1 - 0.069 13.9 0.4 7.3 7.4 0.0 2.9 3 0 0 3 3 2 0 Methyltransferase domain MeaB PF03308.16 KFM24149.1 - 0.074 12.0 1.5 7.6 5.4 0.0 3.2 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DAP3 PF10236.9 KFM24149.1 - 0.08 12.1 1.6 14 4.7 0.1 3.1 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 Adeno_IVa2 PF02456.15 KFM24149.1 - 0.085 11.6 0.0 4 6.1 0.0 2.3 2 0 0 2 2 2 0 Adenovirus IVa2 protein Mg_chelatase PF01078.21 KFM24149.1 - 0.096 12.1 0.3 4.3 6.7 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI KapB PF08810.10 KFM24149.1 - 0.11 12.7 0.6 1.8 8.8 0.0 2.6 2 0 0 2 2 2 0 Kinase associated protein B Roc PF08477.13 KFM24149.1 - 0.11 12.7 0.0 16 5.7 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 KFM24149.1 - 0.11 12.4 0.1 5.6 6.8 0.1 2.9 2 1 0 2 2 2 0 NTPase EcoEI_R_C PF08463.10 KFM24149.1 - 0.14 12.3 3.0 0.96 9.5 0.2 2.7 3 0 0 3 3 2 0 EcoEI R protein C-terminal Dynamin_N PF00350.23 KFM24149.1 - 0.19 11.8 1.0 33 4.5 0.0 3.4 2 1 1 3 3 3 0 Dynamin family Pkinase PF00069.25 KFM24150.1 - 1.4e-25 90.2 0.0 1.7e-25 89.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM24150.1 - 2.3e-13 50.0 0.0 2.9e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFM24150.1 - 8.3e-10 38.0 0.1 1.1e-09 37.7 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFM24150.1 - 6.9e-05 22.9 0.1 0.00034 20.6 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KFM24150.1 - 0.1 12.0 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family VTC PF09359.10 KFM24151.1 - 8.4e-72 241.9 0.0 1.2e-71 241.4 0.0 1.2 1 0 0 1 1 1 1 VTC domain ABC_membrane PF00664.23 KFM24151.1 - 4.6e-56 190.5 27.1 6e-30 104.8 6.9 2.8 3 0 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFM24151.1 - 2.9e-43 147.7 0.0 7.4e-24 84.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SPX PF03105.19 KFM24151.1 - 1.6e-16 61.3 8.0 2.4e-06 27.7 0.1 3.2 2 1 1 3 3 3 3 SPX domain DUF202 PF02656.15 KFM24151.1 - 1.3e-11 44.8 1.5 1.3e-11 44.8 1.5 5.6 5 1 1 6 6 4 1 Domain of unknown function (DUF202) AAA_16 PF13191.6 KFM24151.1 - 3.2e-08 34.1 4.6 0.0018 18.7 0.3 3.1 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 KFM24151.1 - 4.8e-08 33.1 0.1 0.0028 17.7 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase SMC_N PF02463.19 KFM24151.1 - 8.4e-08 31.9 0.4 0.071 12.5 0.0 3.8 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KFM24151.1 - 1.1e-06 28.3 1.0 0.089 12.6 0.1 3.4 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KFM24151.1 - 2.1e-06 27.8 1.4 0.16 11.7 0.1 4.4 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KFM24151.1 - 1e-05 26.1 0.0 0.16 12.4 0.0 2.8 3 0 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 KFM24151.1 - 1.4e-05 25.0 0.3 0.036 14.0 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 KFM24151.1 - 6.7e-05 22.7 0.8 0.16 11.7 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KFM24151.1 - 0.0006 20.1 0.6 4.1 7.7 0.0 3.6 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KFM24151.1 - 0.00085 18.9 0.4 0.062 12.9 0.1 2.9 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KFM24151.1 - 0.0023 17.0 0.1 0.54 9.3 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein Dynamin_N PF00350.23 KFM24151.1 - 0.0025 17.9 4.8 0.3 11.1 0.1 2.4 2 0 0 2 2 2 2 Dynamin family DUF87 PF01935.17 KFM24151.1 - 0.0039 17.3 2.4 2.3 8.3 0.4 2.6 2 0 0 2 2 2 2 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 KFM24151.1 - 0.017 14.5 0.8 1.8 7.8 0.0 2.8 3 0 0 3 3 3 0 FtsK/SpoIIIE family DUF815 PF05673.13 KFM24151.1 - 0.032 13.4 0.3 2 7.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) IIGP PF05049.13 KFM24151.1 - 0.043 12.9 0.6 1.2 8.1 0.1 2.3 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_7 PF12775.7 KFM24151.1 - 0.15 11.5 0.1 18 4.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 KFM24151.1 - 0.21 10.8 1.0 16 4.7 0.2 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_27 PF13514.6 KFM24151.1 - 0.23 11.0 2.9 12 5.4 0.1 3.4 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 KFM24151.1 - 0.43 10.8 1.6 73 3.6 0.1 3.5 3 0 0 3 3 3 0 AAA domain SpoU_methylase PF00588.19 KFM24152.1 - 2e-24 86.4 0.0 2.6e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family AA_kinase PF00696.28 KFM24155.1 - 6e-43 147.2 3.9 7.5e-43 146.9 3.9 1.1 1 0 0 1 1 1 1 Amino acid kinase family CCD PF07860.11 KFM24156.1 - 0.073 13.1 0.0 0.086 12.9 0.0 1.1 1 0 0 1 1 1 0 WisP family C-Terminal Region GP67 PF17634.2 KFM24156.1 - 0.12 12.8 0.8 0.15 12.5 0.8 1.1 1 0 0 1 1 1 0 Gene product 67 DUF2065 PF09838.9 KFM24156.1 - 0.56 10.3 3.1 6.6 6.8 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2065) Myosin_head PF00063.21 KFM24157.1 - 2.2e-181 604.5 0.0 2.7e-158 528.2 0.0 2.1 1 1 1 2 2 2 2 Myosin head (motor domain) AAA_22 PF13401.6 KFM24157.1 - 0.022 15.1 0.6 0.21 11.9 0.1 2.7 2 0 0 2 2 2 0 AAA domain DUF2249 PF10006.9 KFM24157.1 - 0.084 12.7 0.0 0.32 10.9 0.0 2.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2249) AAA_16 PF13191.6 KFM24157.1 - 0.099 13.0 4.3 0.21 12.0 0.0 3.1 3 0 0 3 3 3 0 AAA ATPase domain SH3_19 PF18597.1 KFM24157.1 - 0.18 11.7 0.5 0.37 10.6 0.5 1.5 1 0 0 1 1 1 0 Myosin X N-terminal SH3 domain AAA_10 PF12846.7 KFM24157.1 - 0.26 10.1 0.1 0.38 9.6 0.1 1.1 1 0 0 1 1 1 0 AAA-like domain AAA_6 PF12774.7 KFM24157.1 - 0.34 9.8 0.3 0.56 9.1 0.3 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region BP28CT PF08146.12 KFM24158.1 - 3.3e-31 108.3 0.0 8.8e-31 106.9 0.0 1.7 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 KFM24158.1 - 1e-14 54.9 5.1 1e-14 54.8 2.4 2.5 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 10 Arm PF00514.23 KFM24158.1 - 0.015 15.4 5.9 2.8 8.1 0.1 5.6 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Transglut_core PF01841.19 KFM24158.1 - 0.049 14.1 0.2 0.14 12.6 0.2 1.8 1 0 0 1 1 1 0 Transglutaminase-like superfamily DUF3437 PF11919.8 KFM24158.1 - 0.43 10.5 1.3 3.8 7.5 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3437) HEAT PF02985.22 KFM24158.1 - 8.1 7.0 30.1 0.23 11.8 0.1 7.5 8 0 0 8 8 8 0 HEAT repeat Actin PF00022.19 KFM24160.1 - 6.2e-62 209.5 0.0 3.6e-59 200.4 0.0 2.9 1 1 1 2 2 2 2 Actin TAL_FSA PF00923.19 KFM24161.1 - 2.6e-40 138.6 0.0 3.8e-40 138.1 0.0 1.2 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase ThiF PF00899.21 KFM24162.1 - 4.2e-53 180.2 0.0 6e-53 179.7 0.0 1.2 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 KFM24162.1 - 2.4e-12 47.3 0.0 4e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain TPR_1 PF00515.28 KFM24162.1 - 3.1e-08 33.1 7.9 0.016 15.1 0.3 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat UBA_e1_thiolCys PF10585.9 KFM24162.1 - 3.3e-08 33.8 0.0 1.9e-05 24.7 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site TPR_2 PF07719.17 KFM24162.1 - 6.4e-08 32.1 14.1 0.022 14.8 0.4 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFM24162.1 - 2.5e-05 24.8 8.8 2.5e-05 24.8 8.8 3.9 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFM24162.1 - 0.00093 19.4 5.4 0.23 11.9 0.2 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat E2_bind PF08825.10 KFM24162.1 - 0.001 19.2 0.0 0.0019 18.3 0.0 1.4 1 0 0 1 1 1 1 E2 binding domain TPR_9 PF13371.6 KFM24162.1 - 0.0044 17.2 16.0 0.0049 17.0 13.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFM24162.1 - 0.012 15.9 16.1 0.89 9.9 10.9 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFM24162.1 - 0.032 14.3 0.2 0.032 14.3 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Rhamno_transf PF11316.8 KFM24162.1 - 0.035 13.5 0.0 0.067 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative rhamnosyl transferase DUF3846 PF12957.7 KFM24162.1 - 0.043 14.1 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3846) ANAPC3 PF12895.7 KFM24162.1 - 0.08 13.2 1.1 0.13 12.5 0.1 1.9 2 0 0 2 2 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KFM24162.1 - 0.16 11.7 2.2 0.93 9.2 0.1 2.6 2 0 0 2 2 2 0 TPR repeat DUF2379 PF09543.10 KFM24162.1 - 0.19 12.0 4.1 1.7 8.9 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2379) TPR_14 PF13428.6 KFM24162.1 - 2.3 9.3 33.7 0.22 12.4 7.7 5.5 3 1 2 5 5 4 0 Tetratricopeptide repeat AMMECR1 PF01871.17 KFM24163.1 - 1.9e-43 147.9 0.0 2.3e-43 147.7 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 Pkinase PF00069.25 KFM24164.1 - 2e-51 174.9 0.0 2.7e-51 174.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM24164.1 - 2.2e-51 174.7 0.0 2.9e-51 174.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_5 PF13857.6 KFM24164.1 - 1.1e-09 38.3 0.1 3.3e-09 36.8 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFM24164.1 - 2.2e-08 34.5 0.1 0.00057 20.4 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM24164.1 - 8e-08 32.8 0.0 2.1e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KFM24164.1 - 1.6e-06 28.3 0.0 3.1e-05 24.2 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 KFM24164.1 - 6.1e-05 23.1 0.0 0.00048 20.4 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat APH PF01636.23 KFM24164.1 - 0.00088 19.3 0.9 0.078 12.9 0.1 3.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFM24164.1 - 0.0018 17.1 0.0 0.0025 16.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase ABC_membrane_2 PF06472.15 KFM24165.1 - 1.7e-35 122.7 1.8 9.6e-35 120.3 1.8 1.9 1 1 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KFM24165.1 - 4e-18 66.2 0.0 7e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SbmA_BacA PF05992.12 KFM24165.1 - 5.5e-11 42.5 1.6 7.8e-09 35.4 0.1 2.2 2 0 0 2 2 2 2 SbmA/BacA-like family AAA_16 PF13191.6 KFM24165.1 - 8e-05 23.1 0.3 8e-05 23.1 0.3 2.5 3 1 0 3 3 3 1 AAA ATPase domain NACHT PF05729.12 KFM24165.1 - 0.00023 21.1 0.0 0.0025 17.8 0.0 2.1 2 0 0 2 2 2 1 NACHT domain ABC_membrane PF00664.23 KFM24165.1 - 0.0014 18.3 5.3 0.0015 18.3 0.7 2.1 2 0 0 2 2 2 1 ABC transporter transmembrane region AAA_30 PF13604.6 KFM24165.1 - 0.0038 17.0 0.0 0.045 13.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain Chorion_S16 PF05836.12 KFM24165.1 - 0.0055 16.9 0.7 0.014 15.6 0.7 1.6 1 0 0 1 1 1 1 Chorion protein S16 AAA_21 PF13304.6 KFM24165.1 - 0.0069 16.2 0.0 0.023 14.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KFM24165.1 - 0.016 15.1 0.1 0.03 14.2 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 KFM24165.1 - 0.03 14.6 0.2 0.081 13.2 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KFM24165.1 - 0.031 14.0 0.1 0.11 12.3 0.1 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 KFM24165.1 - 0.078 12.9 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain SMC_N PF02463.19 KFM24165.1 - 0.13 11.6 0.0 5.9 6.3 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Mg_chelatase PF01078.21 KFM24165.1 - 0.15 11.4 0.2 0.28 10.5 0.2 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 KFM24165.1 - 0.21 12.1 0.0 0.36 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KFM24165.1 - 0.22 11.1 3.5 3.2 7.3 0.1 3.0 2 1 1 3 3 3 0 AAA domain HTH_15 PF12324.8 KFM24167.1 - 0.02 14.9 0.3 0.058 13.3 0.3 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase DUF3040 PF11239.8 KFM24167.1 - 0.3 11.4 11.0 1.3 9.4 1.3 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3040) MMR_HSR1 PF01926.23 KFM24169.1 - 1.8e-16 60.2 0.1 1.8e-14 53.8 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFM24169.1 - 3.6e-06 26.6 0.1 2.3e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KFM24169.1 - 0.00028 20.8 0.0 0.065 13.1 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase MeaB PF03308.16 KFM24169.1 - 0.013 14.6 0.1 0.026 13.5 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 KFM24169.1 - 0.04 13.5 0.1 0.47 10.0 0.0 2.3 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AIG1 PF04548.16 KFM24169.1 - 0.2 11.0 0.0 0.36 10.1 0.0 1.3 1 0 0 1 1 1 0 AIG1 family Vps51 PF08700.11 KFM24170.1 - 1.8e-08 34.4 0.4 3.2e-08 33.6 0.4 1.3 1 0 0 1 1 1 1 Vps51/Vps67 VWA_2 PF13519.6 KFM24172.1 - 2.4e-22 79.6 0.3 8e-22 77.9 0.1 1.9 1 1 1 2 2 2 1 von Willebrand factor type A domain Ssl1 PF04056.14 KFM24172.1 - 2.8e-07 30.6 1.0 4.1e-07 30.0 0.2 1.6 2 0 0 2 2 2 1 Ssl1-like UIM PF02809.20 KFM24172.1 - 0.00099 18.9 18.4 0.037 13.9 2.5 3.8 3 0 0 3 3 3 2 Ubiquitin interaction motif Glyco_transf_52 PF07922.11 KFM24172.1 - 0.014 14.7 0.1 0.022 14.0 0.1 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 52 Ribosomal_60s PF00428.19 KFM24172.1 - 0.59 10.8 10.5 1.6 9.4 10.5 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF2924 PF11149.8 KFM24173.1 - 0.049 14.0 0.1 0.078 13.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) BRCT_2 PF16589.5 KFM24174.1 - 2.4e-18 66.3 0.0 1.6e-09 38.1 0.0 3.3 3 0 0 3 3 3 3 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KFM24174.1 - 1.4e-11 44.6 0.0 0.0011 19.3 0.0 4.3 4 1 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 KFM24174.1 - 1.4e-09 37.7 0.0 3.7e-07 30.0 0.0 2.6 3 0 0 3 3 3 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 KFM24174.1 - 1.1e-05 25.2 0.1 0.013 15.5 0.0 3.7 4 0 0 4 4 4 1 twin BRCT domain LIG3_BRCT PF16759.5 KFM24174.1 - 0.00011 22.4 0.0 2.1 8.7 0.1 3.9 4 0 0 4 4 4 1 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 KFM24174.1 - 0.0047 17.0 0.2 1.8 8.7 0.0 3.3 4 0 0 4 4 4 1 BRCA1 C Terminus (BRCT) domain Maf PF02545.14 KFM24175.1 - 3.4e-35 121.4 0.1 3.8e-35 121.2 0.1 1.0 1 0 0 1 1 1 1 Maf-like protein ARID PF01388.21 KFM24176.1 - 2.8e-12 47.1 0.0 4.8e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Bromodomain PF00439.25 KFM24176.1 - 4.3e-07 29.9 0.0 8.5e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Bromodomain DDT PF02791.17 KFM24176.1 - 0.00058 20.1 0.0 0.0014 18.9 0.0 1.6 1 0 0 1 1 1 1 DDT domain LRR_4 PF12799.7 KFM24177.1 - 1.1e-11 44.7 3.9 0.00033 21.0 0.1 4.1 2 2 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFM24177.1 - 1.6e-09 37.5 0.0 6.2e-05 22.6 0.0 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 KFM24177.1 - 3.8e-08 33.0 3.3 0.027 14.2 0.1 4.5 2 1 2 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 KFM24177.1 - 0.0036 17.6 1.7 35 5.5 0.1 4.9 5 1 0 5 5 5 1 Leucine Rich Repeat LSM PF01423.22 KFM24178.1 - 4.2e-18 64.8 0.1 4.8e-18 64.6 0.1 1.1 1 0 0 1 1 1 1 LSM domain AMP-binding PF00501.28 KFM24179.1 - 4.4e-31 107.9 0.2 2.3e-15 56.2 0.2 2.2 1 1 1 2 2 2 2 AMP-binding enzyme ACAS_N PF16177.5 KFM24179.1 - 9.4e-10 38.3 0.0 1.8e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus PG_binding_1 PF01471.18 KFM24180.1 - 8.9e-10 38.6 0.0 1.9e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Amidohydro_1 PF01979.20 KFM24181.1 - 4.6e-21 75.5 0.0 1.2e-09 37.9 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 KFM24181.1 - 7.7e-11 42.1 0.8 3.8e-07 29.9 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Glyco_hydro_9 PF00759.19 KFM24182.1 - 5.4e-82 276.4 18.8 6.7e-82 276.1 18.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Glyco_hydro_9 PF00759.19 KFM24183.1 - 4.7e-97 326.0 18.9 5.5e-97 325.8 18.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Neuropeptide_S PF14993.6 KFM24183.1 - 0.18 11.7 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Neuropeptide S precursor protein Glyco_hydro_9 PF00759.19 KFM24184.1 - 1e-84 285.4 4.8 1.3e-84 285.0 4.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Sec23_trunk PF04811.15 KFM24185.1 - 1.8e-65 220.9 0.0 3e-65 220.2 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KFM24185.1 - 1.3e-21 77.2 0.0 2e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KFM24185.1 - 4.5e-14 52.2 1.7 4.5e-14 52.2 1.7 1.8 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.15 KFM24185.1 - 1.7e-12 47.1 0.0 2.7e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 KFM24185.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Gelsolin repeat Cauli_VI PF01693.16 KFM24188.1 - 1.1e-15 57.7 1.3 1.6e-15 57.1 1.3 1.2 1 0 0 1 1 1 1 Caulimovirus viroplasmin Spc42p PF11544.8 KFM24189.1 - 0.021 14.8 0.0 0.025 14.6 0.0 1.1 1 0 0 1 1 1 0 Spindle pole body component Spc42p DUF4686 PF15742.5 KFM24189.1 - 0.032 13.4 0.3 0.034 13.3 0.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) Macoilin PF09726.9 KFM24189.1 - 0.12 10.9 0.4 0.13 10.8 0.4 1.0 1 0 0 1 1 1 0 Macoilin family ACBP PF00887.19 KFM24190.1 - 1.6e-20 73.1 0.0 2.3e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein Kelch_5 PF13854.6 KFM24190.1 - 3.2e-19 68.5 7.5 1.3e-06 28.3 0.1 5.2 4 1 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 KFM24190.1 - 2.4e-18 66.0 10.3 7.4e-08 32.5 0.0 5.8 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.6 KFM24190.1 - 3.1e-16 59.0 3.2 0.024 14.9 0.0 5.4 4 1 1 5 5 5 5 Kelch motif Kelch_4 PF13418.6 KFM24190.1 - 2.7e-15 56.1 12.9 8.5e-07 28.9 0.0 5.5 5 1 1 6 6 6 3 Galactose oxidase, central domain Kelch_1 PF01344.25 KFM24190.1 - 1.5e-14 53.3 10.5 0.028 14.0 0.0 5.3 4 1 1 5 5 5 5 Kelch motif Kelch_2 PF07646.15 KFM24190.1 - 6.5e-12 44.9 3.9 0.11 12.5 0.0 5.4 4 1 0 4 4 4 4 Kelch motif Pkinase PF00069.25 KFM24191.1 - 2.5e-40 138.5 0.0 3.3e-40 138.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM24191.1 - 4.3e-14 52.4 0.0 5.9e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Lipase_GDSL_2 PF13472.6 KFM24192.1 - 0.00013 22.5 0.0 0.00027 21.4 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Fasciclin PF02469.22 KFM24193.1 - 7.1e-16 58.6 0.1 1.1e-15 58.0 0.1 1.2 1 0 0 1 1 1 1 Fasciclin domain RXLR PF16810.5 KFM24194.1 - 0.0079 16.6 1.0 0.011 16.2 1.0 1.1 1 0 0 1 1 1 1 RXLR phytopathogen effector protein, Avirulence activity PIN_8 PF18476.1 KFM24194.1 - 0.045 13.6 2.0 0.059 13.2 2.0 1.1 1 0 0 1 1 1 0 PIN like domain DUF5635 PF18685.1 KFM24194.1 - 0.059 13.3 0.4 0.14 12.2 0.4 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5635) DUF2277 PF10041.9 KFM24194.1 - 0.086 13.2 0.8 0.17 12.3 0.8 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2277) IPK PF03770.16 KFM24194.1 - 0.13 12.1 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 Inositol polyphosphate kinase Sulfotransfer_4 PF17784.1 KFM24194.1 - 0.15 11.9 0.4 0.2 11.5 0.4 1.1 1 0 0 1 1 1 0 Sulfotransferase domain THOC7 PF05615.13 KFM24194.1 - 0.16 12.3 1.4 0.25 11.6 1.4 1.3 1 1 0 1 1 1 0 Tho complex subunit 7 DUF3584 PF12128.8 KFM24194.1 - 0.16 9.4 4.5 0.2 9.1 4.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Pkinase PF00069.25 KFM24195.1 - 5.3e-48 163.7 0.0 1.5e-47 162.2 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM24195.1 - 4.2e-18 65.6 0.0 3.2e-17 62.7 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 KFM24196.1 - 2.2e-24 85.3 12.7 3.5e-06 27.6 0.2 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat U-box PF04564.15 KFM24196.1 - 1.2e-17 63.8 0.0 1.7e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 U-box domain PQQ_3 PF13570.6 KFM24196.1 - 1.6e-07 31.6 6.6 0.05 14.1 0.1 3.8 4 0 0 4 4 4 3 PQQ-like domain Nup160 PF11715.8 KFM24196.1 - 0.013 14.2 2.5 3.6 6.1 0.5 3.0 1 1 2 3 3 3 0 Nucleoporin Nup120/160 zf-Nse PF11789.8 KFM24196.1 - 0.025 14.4 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 KFM24196.1 - 0.035 14.1 0.8 0.13 12.3 0.0 2.5 3 0 0 3 3 3 0 RING-type zinc-finger zf-rbx1 PF12678.7 KFM24196.1 - 0.043 14.1 0.9 0.55 10.6 0.0 2.6 3 0 0 3 3 3 0 RING-H2 zinc finger domain DEAD PF00270.29 KFM24197.1 - 1.1e-30 106.7 0.0 1.7e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM24197.1 - 4.8e-10 39.8 0.0 7.9e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM24197.1 - 0.0002 21.4 0.0 0.00065 19.7 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit WD40 PF00400.32 KFM24198.1 - 3.2e-06 27.8 1.9 0.17 12.8 0.0 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat PQQ_3 PF13570.6 KFM24198.1 - 0.08 13.5 5.8 0.76 10.3 0.1 4.1 5 1 0 5 5 5 0 PQQ-like domain DnaJ_C PF01556.18 KFM24199.1 - 1.8e-33 115.7 0.1 2.7e-33 115.2 0.1 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KFM24199.1 - 1.7e-22 79.3 3.8 2.7e-22 78.6 3.8 1.3 1 0 0 1 1 1 1 DnaJ domain CxC3 PF18804.1 KFM24199.1 - 0.057 13.3 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases LPD7 PF18821.1 KFM24199.1 - 0.097 12.8 0.2 0.21 11.7 0.2 1.5 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 7 DEAD_2 PF06733.15 KFM24201.1 - 4.4e-44 150.2 0.0 6.2e-44 149.7 0.0 1.2 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.6 KFM24201.1 - 1.6e-42 145.6 0.0 3.2e-42 144.6 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.15 KFM24201.1 - 0.00039 20.5 0.0 0.11 12.4 0.0 2.2 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 KFM24201.1 - 0.0027 17.5 0.2 0.068 12.9 0.2 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_25 PF13481.6 KFM24201.1 - 0.039 13.5 0.0 0.15 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain SNF2_N PF00176.23 KFM24201.1 - 0.11 11.2 0.3 0.17 10.5 0.3 1.4 1 1 0 1 1 1 0 SNF2 family N-terminal domain PhoH PF02562.16 KFM24201.1 - 0.22 11.0 0.0 1 8.7 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein zf-RING_2 PF13639.6 KFM24202.1 - 0.044 14.1 1.3 0.13 12.6 1.3 1.8 1 0 0 1 1 1 0 Ring finger domain zf-ANAPC11 PF12861.7 KFM24202.1 - 0.16 12.0 0.2 0.16 12.0 0.2 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger THOC7 PF05615.13 KFM24203.1 - 3.7e-07 30.5 1.2 1.7e-05 25.1 0.8 2.3 1 1 1 2 2 2 2 Tho complex subunit 7 DUF4407 PF14362.6 KFM24203.1 - 0.0027 17.1 3.6 0.0032 16.9 3.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) FliJ PF02050.16 KFM24203.1 - 0.016 15.4 0.8 0.13 12.5 0.1 2.1 1 1 1 2 2 2 0 Flagellar FliJ protein Fer2 PF00111.27 KFM24204.1 - 1.1e-20 73.4 0.2 1.4e-20 73.0 0.2 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 KFM24204.1 - 0.045 13.8 0.0 0.09 12.8 0.0 1.6 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain FKBP_C PF00254.28 KFM24205.1 - 1.4e-30 105.5 0.0 3e-30 104.4 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 KFM24205.1 - 8.4e-15 55.2 0.0 1.5e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 Nucleoplasmin-like domain Iso_dh PF00180.20 KFM24206.1 - 5.3e-130 433.6 0.0 6.1e-130 433.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase IMS PF00817.20 KFM24209.1 - 9.2e-68 227.0 0.0 7.9e-38 129.8 0.0 2.9 2 1 0 2 2 2 2 impB/mucB/samB family IMS_C PF11799.8 KFM24209.1 - 9e-13 49.0 0.0 1.1e-07 32.5 0.0 2.6 2 0 0 2 2 2 2 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KFM24209.1 - 1.5e-09 37.6 0.0 6.7e-06 26.1 0.0 2.7 2 0 0 2 2 2 2 IMS family HHH motif Cdd1 PF11731.8 KFM24209.1 - 0.019 15.2 0.5 0.47 10.7 0.0 2.6 3 0 0 3 3 3 0 Pathogenicity locus TfoX_C PF04994.13 KFM24209.1 - 0.13 12.4 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 TfoX C-terminal domain APH PF01636.23 KFM24210.1 - 8.8e-44 150.2 0.1 8.8e-44 150.2 0.1 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Acyl-CoA_dh_1 PF00441.24 KFM24210.1 - 4.8e-35 121.0 4.9 1e-34 119.9 4.9 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KFM24210.1 - 3e-18 65.8 0.0 5.6e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFM24210.1 - 9e-13 48.7 11.6 1.8e-12 47.7 11.6 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KFM24210.1 - 7e-11 42.8 0.5 5.3e-10 39.9 0.5 2.3 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain HD PF01966.22 KFM24211.1 - 4.9e-13 49.4 1.4 9e-13 48.5 1.4 1.5 1 0 0 1 1 1 1 HD domain PDEase_I PF00233.19 KFM24211.1 - 0.054 13.2 0.6 0.5 10.1 0.2 2.1 2 0 0 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase YGGT PF02325.17 KFM24212.1 - 7.1e-16 58.4 8.1 9.3e-16 58.0 8.1 1.2 1 0 0 1 1 1 1 YGGT family YqhR PF11085.8 KFM24213.1 - 0.057 13.3 0.8 0.075 13.0 0.8 1.1 1 0 0 1 1 1 0 Conserved membrane protein YqhR DUF533 PF04391.12 KFM24213.1 - 3.2 7.3 5.8 4 7.0 5.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF533) DRY_EERY PF09750.9 KFM24214.1 - 0.0015 18.8 1.2 0.0031 17.8 0.4 1.8 2 0 0 2 2 2 1 Alternative splicing regulator Rer1 PF03248.13 KFM24215.1 - 3e-66 222.4 6.1 3.6e-66 222.1 6.1 1.1 1 0 0 1 1 1 1 Rer1 family Lactamase_B PF00753.27 KFM24217.1 - 6.8e-12 45.8 0.2 5.5e-11 42.8 0.0 2.2 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Methyltransf_16 PF10294.9 KFM24217.1 - 6.9e-11 42.2 0.0 1.1e-05 25.3 0.0 2.3 2 0 0 2 2 2 2 Lysine methyltransferase Lactamase_B_2 PF12706.7 KFM24217.1 - 1.2e-10 41.2 0.7 1.1e-05 25.0 0.1 2.8 3 0 0 3 3 3 2 Beta-lactamase superfamily domain PrmA PF06325.13 KFM24217.1 - 0.00023 20.6 0.0 0.00036 20.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) SAP PF02037.27 KFM24217.1 - 0.00031 20.4 1.3 0.00038 20.1 0.1 1.8 2 0 0 2 2 2 1 SAP domain MTS PF05175.14 KFM24217.1 - 0.0034 16.9 0.1 0.0058 16.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 KFM24217.1 - 0.0074 16.1 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Thioredoxin PF00085.20 KFM24218.1 - 3.9e-08 33.2 0.0 6.6e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Mito_carr PF00153.27 KFM24222.1 - 1.4e-64 214.0 1.6 2e-22 78.9 0.0 3.6 3 0 0 3 3 3 3 Mitochondrial carrier protein ABC1 PF03109.16 KFM24222.1 - 4.2e-24 85.0 0.0 6.9e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 ABC1 family SUFU PF05076.13 KFM24222.1 - 0.07 13.1 0.0 19 5.2 0.0 2.4 2 0 0 2 2 2 0 Suppressor of fused protein (SUFU) Mg_trans_NIPA PF05653.14 KFM24223.1 - 1.3e-08 34.3 3.9 2.1e-08 33.7 3.9 1.3 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KFM24223.1 - 0.0019 18.4 2.0 0.0019 18.4 2.0 2.9 3 1 0 3 3 3 1 EamA-like transporter family MFS_1_like PF12832.7 KFM24225.1 - 1.7e-41 142.4 0.0 2.3e-40 138.7 0.0 2.1 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KFM24225.1 - 5.8e-15 55.1 24.3 2.1e-14 53.3 24.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily LacY_symp PF01306.19 KFM24225.1 - 0.0084 14.9 0.6 0.038 12.8 0.6 1.8 1 1 0 1 1 1 1 LacY proton/sugar symporter Frataxin_Cyay PF01491.16 KFM24227.1 - 2.7e-08 33.9 0.0 2.4e-07 30.8 0.0 2.0 1 1 0 1 1 1 1 Frataxin-like domain Na_Ca_ex PF01699.24 KFM24229.1 - 2.5e-35 121.7 27.2 1.5e-18 67.2 11.9 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF485 PF04341.12 KFM24229.1 - 8.3 6.4 7.8 2.6 8.0 2.6 2.8 2 0 0 2 2 2 0 Protein of unknown function, DUF485 zf-CCCH_2 PF14608.6 KFM24230.1 - 4.8 7.8 9.8 16 6.2 0.8 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger 2OG-FeII_Oxy_3 PF13640.6 KFM24231.1 - 1.7e-16 60.9 0.0 2.7e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 KFM24231.1 - 1.1e-09 38.8 0.0 1.7e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Methyltransf_10 PF05971.12 KFM24232.1 - 5.8e-36 124.4 0.0 9.7e-36 123.6 0.0 1.2 1 0 0 1 1 1 1 RNA methyltransferase Aldose_epim PF01263.20 KFM24235.1 - 0.034 13.5 0.0 0.054 12.8 0.0 1.3 1 1 0 1 1 1 0 Aldose 1-epimerase Ribosomal_L5_C PF00673.21 KFM24237.1 - 1.3e-21 76.5 0.0 2e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KFM24237.1 - 1.5e-21 76.5 0.0 2.8e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 Cupin_6 PF12852.7 KFM24237.1 - 0.088 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Cupin HTH_ABP1_N PF18107.1 KFM24237.1 - 0.14 11.9 0.3 0.83 9.4 0.1 2.0 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain ELFV_dehydrog PF00208.21 KFM24238.1 - 1.2e-69 234.7 0.0 1.9e-69 234.1 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 KFM24238.1 - 2.6e-52 176.1 0.0 5.2e-52 175.2 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain AdoHcyase_NAD PF00670.21 KFM24238.1 - 0.00028 21.0 0.1 0.00056 20.0 0.1 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KFM24238.1 - 0.0053 16.1 0.1 0.011 15.1 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPP_enzyme_N PF02776.18 KFM24239.1 - 7.1e-34 116.9 1.7 1.1e-33 116.2 0.4 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KFM24239.1 - 1.1e-22 80.2 0.0 2.2e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KFM24239.1 - 1.1e-15 57.7 1.2 7.5e-15 55.0 0.1 2.7 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Bac_rhamnosid_N PF08531.10 KFM24239.1 - 0.15 11.9 0.1 0.25 11.2 0.1 1.3 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain ubiquitin PF00240.23 KFM24240.1 - 0.00025 20.7 0.0 0.0017 18.0 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin family EPSP_synthase PF00275.20 KFM24241.1 - 1.6e-132 442.1 0.0 1.8e-132 442.0 0.0 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DUF572 PF04502.13 KFM24242.1 - 4.8e-58 197.4 10.8 8.7e-56 189.9 10.5 2.1 1 1 1 2 2 2 2 Family of unknown function (DUF572) zf-FCS PF06467.14 KFM24242.1 - 0.16 11.9 5.7 0.52 10.3 0.6 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif C1_4 PF07975.12 KFM24242.1 - 0.21 11.8 3.8 0.66 10.2 1.1 2.2 2 0 0 2 2 2 0 TFIIH C1-like domain IBR PF01485.21 KFM24242.1 - 0.21 11.8 2.4 0.36 11.1 2.4 1.3 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-AN1 PF01428.16 KFM24242.1 - 0.24 11.6 2.7 1.7 8.9 0.6 2.2 2 0 0 2 2 2 0 AN1-like Zinc finger C1_2 PF03107.16 KFM24242.1 - 1 9.7 6.8 9.9 6.6 0.3 2.2 2 0 0 2 2 2 0 C1 domain DJ-1_PfpI PF01965.24 KFM24243.1 - 1.5e-17 63.9 0.0 1.8e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GDI PF00996.18 KFM24244.1 - 3.5e-209 694.7 0.0 4e-209 694.5 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 KFM24244.1 - 0.041 14.1 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain RPN7 PF10602.9 KFM24246.1 - 1.1e-32 113.2 0.3 1.4e-32 112.8 0.3 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KFM24246.1 - 6.8e-08 33.0 0.0 1.4e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 PCI domain Ntox1 PF15500.6 KFM24246.1 - 0.17 12.2 1.1 20 5.6 0.0 2.8 3 0 0 3 3 3 0 Putative RNase-like toxin, toxin_1 7tm_3 PF00003.22 KFM24247.1 - 0.00041 20.2 1.3 0.00059 19.6 1.3 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF2070 PF09843.9 KFM24247.1 - 0.048 12.0 1.1 0.055 11.8 1.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Yip1 PF04893.17 KFM24247.1 - 0.78 9.4 18.0 2.4 7.9 18.0 1.8 1 1 0 1 1 1 0 Yip1 domain MARVEL PF01284.23 KFM24247.1 - 1.6 8.8 8.6 3.1 7.8 8.6 1.4 1 1 0 1 1 1 0 Membrane-associating domain DUF1761 PF08570.10 KFM24247.1 - 5.1 7.4 12.7 4.7 7.5 4.2 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1761) Rotamase PF00639.21 KFM24248.1 - 1.5e-17 64.3 0.0 1.8e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 KFM24248.1 - 5.6e-17 62.3 0.0 7.6e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 KFM24248.1 - 8.8e-08 33.0 0.0 9.4e-08 32.9 0.0 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain CwfJ_C_1 PF04677.15 KFM24249.1 - 3.3e-32 110.9 0.0 4.7e-32 110.4 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 KFM24249.1 - 5.5e-22 78.5 0.7 3.1e-21 76.1 0.0 2.3 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 Sulfate_transp PF00916.20 KFM24250.1 - 3.5e-86 289.3 9.8 4.5e-86 289.0 9.8 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KFM24250.1 - 1.9e-16 59.8 0.0 2.9e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KFM24250.1 - 9.5e-06 25.9 0.2 9.5e-06 25.9 0.2 3.0 3 0 0 3 3 3 1 STAS domain LssY_C PF14067.6 KFM24250.1 - 0.19 11.3 0.0 0.47 10.0 0.0 1.6 2 0 0 2 2 2 0 LssY C-terminus SMC_Nse1 PF07574.13 KFM24251.1 - 3.3e-06 27.1 0.0 0.00079 19.4 0.0 2.5 1 1 1 2 2 2 2 Nse1 non-SMC component of SMC5-6 complex TPR_2 PF07719.17 KFM24251.1 - 0.00039 20.3 3.2 4.6 7.6 0.4 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFM24251.1 - 0.047 14.0 3.7 9.7 6.6 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat PTS_IIA PF02255.16 KFM24251.1 - 0.16 12.0 0.1 0.36 10.9 0.1 1.5 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIA subunit TPR_1 PF00515.28 KFM24251.1 - 0.21 11.4 1.5 29 4.7 0.7 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFM24251.1 - 5.7 7.7 18.1 3.3 8.4 3.4 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat Abhydrolase_1 PF00561.20 KFM24252.1 - 5.6e-09 36.0 0.1 3.3e-08 33.5 0.1 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFM24252.1 - 3.7e-06 26.4 0.1 5.7e-06 25.8 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 KFM24252.1 - 0.0004 20.1 0.0 0.00057 19.6 0.0 1.3 1 1 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.7 KFM24252.1 - 0.0071 17.0 3.3 0.0072 16.9 1.6 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KFM24252.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.5 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Lipase PF00151.19 KFM24252.1 - 0.35 10.1 0.7 0.98 8.7 0.0 1.8 2 0 0 2 2 2 0 Lipase PEP_mutase PF13714.6 KFM24253.1 - 8e-48 163.0 1.0 9.1e-48 162.8 1.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KFM24253.1 - 1.8e-09 36.7 0.5 2.3e-09 36.3 0.5 1.1 1 0 0 1 1 1 1 Isocitrate lyase family ComA PF02679.15 KFM24253.1 - 0.2 11.1 0.1 0.8 9.1 0.1 1.8 2 0 0 2 2 2 0 (2R)-phospho-3-sulfolactate synthase (ComA) CBF PF03914.17 KFM24254.1 - 2.9e-32 112.0 0.2 6.1e-32 111.0 0.2 1.6 1 0 0 1 1 1 1 CBF/Mak21 family DUF4064 PF13273.6 KFM24255.1 - 0.19 12.0 8.5 0.5 10.7 8.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) ABC2_membrane_2 PF12679.7 KFM24255.1 - 0.35 10.1 14.9 0.61 9.3 14.9 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein Chromate_transp PF02417.15 KFM24255.1 - 0.43 10.7 12.2 0.59 10.3 12.2 1.1 1 0 0 1 1 1 0 Chromate transporter Cadherin_C_2 PF16492.5 KFM24255.1 - 3.8 8.3 8.6 2.8e+02 2.4 8.6 2.7 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal mTERF PF02536.14 KFM24256.1 - 1.7e-37 129.1 0.0 2.4e-20 72.7 0.0 2.1 1 1 1 2 2 2 2 mTERF PGA2 PF07543.12 KFM24256.1 - 0.032 14.2 0.4 0.05 13.6 0.4 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 DUF3449 PF11931.8 KFM24257.1 - 2.6e-65 219.7 0.1 5.7e-65 218.6 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 KFM24257.1 - 1.2e-21 77.0 0.0 2.4e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 KFM24257.1 - 3.4e-08 33.2 0.0 9.1e-08 31.8 0.0 1.8 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain Telomere_Sde2_2 PF13297.6 KFM24257.1 - 0.1 12.2 0.1 0.37 10.5 0.1 2.0 1 0 0 1 1 1 0 Telomere stability C-terminal zf-C2H2_4 PF13894.6 KFM24257.1 - 0.22 12.4 0.1 0.73 10.8 0.1 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger FUSC PF04632.12 KFM24257.1 - 4.1 5.8 10.2 0.27 9.7 2.4 2.1 1 1 1 2 2 2 0 Fusaric acid resistance protein family HTH_9 PF08221.11 KFM24258.1 - 1.6e-11 44.1 0.2 1.1e-07 31.8 0.0 2.7 2 0 0 2 2 2 2 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.13 KFM24258.1 - 5.1e-06 26.4 0.0 1.1e-05 25.4 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase III subunit RPC82 DUF2046 PF09755.9 KFM24259.1 - 8.4e-31 107.3 40.6 1.4e-24 86.9 32.1 2.1 1 1 1 2 2 2 2 Uncharacterized conserved protein H4 (DUF2046) Golgin_A5 PF09787.9 KFM24259.1 - 0.0048 16.4 20.5 0.0048 16.4 20.5 2.1 1 1 1 2 2 2 1 Golgin subfamily A member 5 HALZ PF02183.18 KFM24259.1 - 0.077 13.2 0.6 0.077 13.2 0.6 5.9 5 2 3 8 8 8 0 Homeobox associated leucine zipper SYCE1 PF15233.6 KFM24259.1 - 0.88 9.6 36.8 0.027 14.5 15.9 3.2 1 1 2 3 3 3 0 Synaptonemal complex central element protein 1 TORC_N PF12884.7 KFM24259.1 - 1.5 9.6 6.7 4.9 8.0 0.1 3.2 3 0 0 3 3 3 0 Transducer of regulated CREB activity, N terminus EDR1 PF14381.6 KFM24259.1 - 1.7 8.3 5.9 3.6 7.2 5.9 1.7 1 1 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 DUF3828 PF12883.7 KFM24259.1 - 5.8 7.3 6.1 5.5 7.4 0.5 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3828) LCIB_C_CA PF18599.1 KFM24259.1 - 7.4 5.8 11.2 0.5 9.6 2.9 2.3 1 1 1 2 2 2 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases DUF1664 PF07889.12 KFM24259.1 - 8.4 6.5 16.3 0.48 10.5 4.7 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Thioredoxin_4 PF13462.6 KFM24259.1 - 8.7 6.5 9.8 0.27 11.4 0.7 2.4 1 1 0 2 2 2 0 Thioredoxin Ribonuclease_T2 PF00445.18 KFM24260.1 - 1.9e-35 122.8 0.0 2.3e-35 122.5 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family DUF456 PF04306.13 KFM24260.1 - 0.027 14.8 0.3 1.8 8.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF456) DUF4307 PF14155.6 KFM24260.1 - 0.056 13.3 0.1 0.056 13.3 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) PSI_PsaE PF02427.17 KFM24262.1 - 1.7e-33 114.1 2.3 2.3e-33 113.7 2.3 1.2 1 0 0 1 1 1 1 Photosystem I reaction centre subunit IV / PsaE KOW PF00467.29 KFM24262.1 - 2.3 8.3 5.0 4.7 7.3 0.5 3.1 4 0 0 4 4 4 0 KOW motif Peptidase_M24 PF00557.24 KFM24263.1 - 1.5e-49 168.5 0.3 1.9e-49 168.2 0.3 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 KFM24263.1 - 4.6e-13 49.2 9.2 1e-12 48.1 9.2 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KFM24263.1 - 0.00021 21.3 8.1 0.00049 20.1 8.1 1.7 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 KFM24263.1 - 0.0088 15.9 3.8 0.02 14.8 3.8 1.6 1 0 0 1 1 1 1 HIT zinc finger Phosphorylase PF00343.20 KFM24264.1 - 3.5e-289 961.1 0.0 3.2e-159 531.5 0.0 2.0 2 0 0 2 2 2 2 Carbohydrate phosphorylase DnaJ PF00226.31 KFM24265.1 - 5.7e-25 87.2 1.4 8.9e-25 86.6 1.4 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 KFM24265.1 - 3.4e-19 69.4 0.0 1.5e-17 64.0 0.0 2.2 2 0 0 2 2 2 1 DnaJ C terminal domain LprI PF07007.12 KFM24265.1 - 0.01 16.5 0.1 0.022 15.4 0.1 1.5 1 0 0 1 1 1 0 Lysozyme inhibitor LprI tRNA-synt_2b PF00587.25 KFM24266.1 - 3.1e-36 125.0 0.0 5.7e-36 124.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KFM24266.1 - 5.6e-17 61.7 2.9 1.6e-16 60.2 1.7 2.2 2 0 0 2 2 2 1 Anticodon binding domain TGS PF02824.21 KFM24266.1 - 8.6e-14 51.3 0.1 2.1e-13 50.1 0.1 1.7 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.14 KFM24266.1 - 5.9e-08 32.7 0.0 1.2e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Chordopox_A20R PF05941.13 KFM24266.1 - 0.00068 18.7 0.0 0.0012 17.9 0.0 1.3 1 0 0 1 1 1 1 Chordopoxvirus A20R protein Ccdc124 PF06244.12 KFM24267.1 - 1.7e-29 103.0 13.7 2.4e-29 102.5 13.7 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 Peptidase_C1 PF00112.23 KFM24268.1 - 7.8e-59 199.4 1.2 1.1e-58 198.9 1.2 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 KFM24268.1 - 4.5e-07 30.2 0.0 1.2e-06 28.9 0.0 1.7 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 KFM24268.1 - 0.0062 15.4 2.3 0.027 13.3 0.1 2.0 2 0 0 2 2 2 1 Peptidase C1-like family tRNA-synt_1 PF00133.22 KFM24269.1 - 8.3e-112 374.4 0.0 9.7e-112 374.2 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KFM24269.1 - 1.2e-22 80.5 0.0 1.8e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA zf-FPG_IleRS PF06827.14 KFM24269.1 - 1.1e-07 31.5 3.3 2.2e-07 30.6 3.3 1.5 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS DUF905 PF06006.12 KFM24269.1 - 0.015 15.3 0.1 1.6 8.8 0.0 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF905) tRNA-synt_1g PF09334.11 KFM24269.1 - 0.21 10.3 0.0 1.1 8.0 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KFM24270.1 - 4.1e-17 61.7 0.1 4.6e-17 61.5 0.1 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KFM24270.1 - 0.00094 18.0 0.0 0.0012 17.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) Ysc84 PF04366.12 KFM24271.1 - 7.3e-16 58.1 0.1 1e-15 57.6 0.1 1.2 1 0 0 1 1 1 1 Las17-binding protein actin regulator AA_permease_2 PF13520.6 KFM24272.1 - 6e-35 120.9 26.7 7.4e-35 120.6 26.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFM24272.1 - 8.1e-20 70.9 19.0 1.2e-19 70.3 19.0 1.2 1 0 0 1 1 1 1 Amino acid permease TIM21 PF08294.11 KFM24274.1 - 1.1e-23 83.7 0.0 1.5e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 KFM24274.1 - 0.00023 20.9 0.0 0.0005 19.8 0.0 1.5 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF4244 PF14029.6 KFM24274.1 - 0.13 11.7 3.4 0.23 11.0 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4244) RPAP2_Rtr1 PF04181.13 KFM24275.1 - 3.8e-08 33.5 0.0 7.6e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Rtr1/RPAP2 family DnaJ PF00226.31 KFM24276.1 - 3.1e-21 75.2 0.4 4.9e-21 74.6 0.4 1.3 1 0 0 1 1 1 1 DnaJ domain TPR_2 PF07719.17 KFM24276.1 - 1e-11 44.0 8.0 0.022 14.8 0.4 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFM24276.1 - 5.6e-08 33.0 24.1 0.0011 19.6 0.1 5.6 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFM24276.1 - 6.4e-07 28.9 0.5 0.4 10.6 0.0 4.3 5 0 0 5 5 5 3 Tetratricopeptide repeat BTAD PF03704.17 KFM24276.1 - 0.0016 18.9 13.7 0.52 10.7 5.6 3.2 1 1 1 2 2 2 2 Bacterial transcriptional activator domain TPR_16 PF13432.6 KFM24276.1 - 0.0022 18.6 35.2 0.24 12.1 3.0 5.4 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 KFM24276.1 - 0.0039 16.8 0.7 0.31 10.8 0.1 4.0 5 0 0 5 5 5 1 TPR repeat ChAPs PF09295.10 KFM24276.1 - 0.0047 16.0 0.0 0.0065 15.5 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 KFM24276.1 - 0.0048 17.4 10.5 0.54 10.8 0.0 4.1 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFM24276.1 - 0.011 16.0 7.2 0.011 16.0 7.2 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFM24276.1 - 0.043 13.9 0.0 34 4.6 0.0 4.0 3 1 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 KFM24276.1 - 0.049 13.8 16.3 1.5 9.0 1.5 4.0 2 1 1 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFM24276.1 - 0.096 13.1 0.7 1.6 9.3 0.0 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat DUF5588 PF17826.1 KFM24276.1 - 0.2 10.5 0.0 0.97 8.3 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5588) Ribosomal_L35p PF01632.19 KFM24277.1 - 3.2e-16 59.6 5.9 3.9e-16 59.3 5.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L35 Ribosomal_S8e PF01201.22 KFM24278.1 - 1.5e-55 187.2 0.1 1.9e-55 186.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e UxaE PF16257.5 KFM24278.1 - 0.044 12.4 0.0 0.057 12.1 0.0 1.1 1 0 0 1 1 1 0 tagaturonate epimerase Atg8 PF02991.16 KFM24279.1 - 1.6e-30 105.4 0.8 1.9e-30 105.1 0.8 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Chloroa_b-bind PF00504.21 KFM24280.1 - 2.3e-50 171.3 0.0 3e-50 170.9 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein KH_1 PF00013.29 KFM24281.1 - 8.3e-07 28.7 0.0 1.6e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 KH domain Radical_SAM PF04055.21 KFM24282.1 - 2.4e-12 47.6 0.0 4e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 KFM24282.1 - 0.0034 17.5 0.0 0.0048 17.0 0.0 1.2 1 0 0 1 1 1 1 4Fe-4S single cluster domain YjcB PF15940.5 KFM24282.1 - 0.043 14.0 0.0 0.17 12.1 0.1 1.9 2 0 0 2 2 2 0 Family of unknown function Fer4_12 PF13353.6 KFM24282.1 - 0.19 12.0 0.0 0.29 11.4 0.0 1.2 1 0 0 1 1 1 0 4Fe-4S single cluster domain AA_kinase PF00696.28 KFM24283.1 - 1.3e-12 47.9 0.1 2.3e-12 47.0 0.1 1.4 1 0 0 1 1 1 1 Amino acid kinase family Acetyltransf_1 PF00583.25 KFM24283.1 - 7.7e-07 29.4 0.1 1.7e-06 28.2 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFM24283.1 - 4.3e-06 27.1 0.2 0.00012 22.4 0.2 2.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFM24283.1 - 0.00038 20.4 0.0 0.00069 19.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain UCH PF00443.29 KFM24284.1 - 1.9e-46 158.7 0.0 2.6e-46 158.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 KFM24284.1 - 4.3e-44 150.6 0.0 1.4e-43 148.9 0.0 1.8 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 KFM24284.1 - 1.2e-34 119.8 0.0 2.1e-34 119.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal UCH_1 PF13423.6 KFM24284.1 - 1.4e-18 67.6 0.0 7.6e-18 65.2 0.0 2.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 KFM24284.1 - 3.4e-14 53.0 0.0 6.8e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 MATH domain YukD PF08817.10 KFM24284.1 - 0.044 14.5 0.2 9.5 7.0 0.0 2.7 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD cwf18 PF08315.12 KFM24285.1 - 3.5e-25 89.2 0.9 4.1e-25 89.0 0.9 1.0 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor RNA_pol_Rpb2_6 PF00562.28 KFM24286.1 - 7.6e-115 384.1 0.0 7.3e-114 380.9 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KFM24286.1 - 1.5e-53 181.3 0.0 2e-53 180.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 KFM24286.1 - 2.8e-29 101.3 0.1 6.6e-29 100.1 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 KFM24286.1 - 2e-20 73.2 0.0 3.8e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.16 KFM24286.1 - 1.1e-19 70.4 0.0 2.4e-19 69.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KFM24286.1 - 4.9e-08 33.4 2.1 4.7e-07 30.3 2.1 2.5 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_4 PF04566.13 KFM24286.1 - 2.2e-06 27.8 0.3 1e-05 25.7 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 Tubulin PF00091.25 KFM24287.1 - 8.4e-62 208.9 0.0 1.2e-61 208.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFM24287.1 - 1.6e-15 57.4 0.2 2.3e-15 56.9 0.2 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KFM24287.1 - 0.0002 21.6 0.0 0.0005 20.4 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KFM24287.1 - 0.0012 18.6 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 KFM24287.1 - 0.0021 17.3 0.0 0.0031 16.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin like SNF2_N PF00176.23 KFM24288.1 - 4.9e-61 206.4 0.0 8.2e-61 205.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFM24288.1 - 9.3e-10 38.8 0.0 2e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.6 KFM24288.1 - 3.2e-09 37.0 3.7 6.2e-09 36.0 3.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KFM24288.1 - 2.1e-07 30.7 3.0 3.8e-07 29.9 3.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFM24288.1 - 5.7e-07 29.3 3.4 1.2e-06 28.2 3.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM24288.1 - 1.2e-06 28.3 4.9 2.1e-06 27.6 4.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFM24288.1 - 4.4e-05 23.4 4.9 9.2e-05 22.4 4.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KFM24288.1 - 0.00017 21.4 4.1 0.0006 19.6 4.2 1.9 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KFM24288.1 - 0.00085 19.1 3.1 0.0016 18.3 3.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFM24288.1 - 0.013 15.3 8.0 0.01 15.6 3.2 2.5 2 0 0 2 2 2 0 RING-like zinc finger zf-FLZ PF04570.14 KFM24288.1 - 0.013 15.0 1.9 0.027 13.9 1.9 1.5 1 0 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 zf-RING_4 PF14570.6 KFM24288.1 - 0.061 13.1 4.6 0.11 12.3 4.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KFM24288.1 - 0.089 13.1 2.0 0.2 12.0 2.0 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain Prok-RING_1 PF14446.6 KFM24288.1 - 0.12 12.3 5.0 0.32 10.9 5.0 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-RING_10 PF16685.5 KFM24288.1 - 5.7 7.2 5.1 12 6.1 5.1 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 KFM24288.1 - 6.9 6.9 7.0 15 5.8 7.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Proteasome PF00227.26 KFM24289.1 - 1.7e-58 197.3 0.1 2.5e-58 196.7 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit LXG PF04740.12 KFM24289.1 - 0.0011 18.8 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 LXG domain of WXG superfamily YgaB PF14182.6 KFM24289.1 - 0.2 12.1 2.3 0.5 10.8 2.3 1.7 1 0 0 1 1 1 0 YgaB-like protein SIP PF04954.13 KFM24289.1 - 1.7 9.2 9.5 7.1 7.2 5.8 2.7 3 0 0 3 3 3 0 Siderophore-interacting protein TEX13 PF15186.6 KFM24289.1 - 3.6 7.3 13.1 12 5.6 7.1 2.3 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family Symplekin_C PF12295.8 KFM24290.1 - 2.3e-18 67.0 0.0 5.5e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal DUF3453 PF11935.8 KFM24290.1 - 1.4e-05 24.9 0.0 3.9e-05 23.4 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) Sec6 PF06046.13 KFM24291.1 - 9.9e-50 169.5 0.0 3e-33 115.1 0.0 2.9 2 1 0 2 2 2 2 Exocyst complex component Sec6 DUF2717 PF10911.8 KFM24291.1 - 0.0015 18.2 0.2 1.4 8.7 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF2717) tRNA_int_end_N2 PF12928.7 KFM24292.1 - 2.3e-11 43.7 0.1 2.9e-10 40.2 0.0 2.2 2 0 0 2 2 2 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 KFM24292.1 - 0.14 11.9 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain 2OG-FeII_Oxy PF03171.20 KFM24293.1 - 0.00071 20.0 0.0 0.0011 19.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily OB_NTP_bind PF07717.16 KFM24295.1 - 5.9e-17 61.8 0.0 1.1e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KFM24295.1 - 1.2e-15 57.7 0.1 2.2e-15 56.8 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KFM24295.1 - 1.2e-14 54.6 0.0 2.6e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KFM24295.1 - 8.3e-06 26.1 0.0 2.3e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 KFM24295.1 - 4.6e-05 23.2 0.1 0.00011 22.0 0.1 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 KFM24295.1 - 0.00038 20.2 0.1 0.00038 20.2 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KFM24295.1 - 0.0029 17.9 0.0 0.0063 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KFM24295.1 - 0.0076 16.8 0.4 1.2 9.6 0.2 2.3 1 1 1 2 2 2 1 ABC transporter AAA_16 PF13191.6 KFM24295.1 - 0.01 16.2 1.0 0.077 13.4 1.0 2.5 1 1 0 1 1 1 0 AAA ATPase domain SRP54 PF00448.22 KFM24295.1 - 0.052 13.2 0.6 0.14 11.7 0.6 1.8 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Ribonuclease_3 PF00636.26 KFM24296.1 - 6.7e-31 107.0 0.0 1.8e-15 57.5 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KFM24296.1 - 1.4e-25 89.9 0.0 2.3e-12 47.2 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.14 KFM24296.1 - 1.8e-15 56.8 0.0 4.6e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.31 KFM24296.1 - 1.1e-14 54.7 0.1 2.8e-14 53.4 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFM24296.1 - 2.3e-12 47.0 0.0 4.5e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KFM24296.1 - 6.3e-11 42.6 0.0 1.2e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PAZ PF02170.22 KFM24296.1 - 0.00091 19.0 0.0 0.0022 17.8 0.0 1.6 1 0 0 1 1 1 1 PAZ domain SWI2_SNF2 PF18766.1 KFM24296.1 - 0.13 11.9 0.0 1.1 8.9 0.0 2.4 2 1 0 2 2 2 0 SWI2/SNF2 ATPase Trypsin_2 PF13365.6 KFM24298.1 - 1.3e-05 26.2 2.3 0.00035 21.5 0.0 3.0 2 1 0 2 2 2 1 Trypsin-like peptidase domain Porin_3 PF01459.22 KFM24299.1 - 0.022 14.2 0.0 0.034 13.6 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic porin Metalloenzyme PF01676.18 KFM24301.1 - 2e-91 305.8 0.0 2.4e-91 305.5 0.0 1.1 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.13 KFM24301.1 - 1.1e-54 185.2 0.0 1.5e-54 184.7 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) PGM_PMM_II PF02879.16 KFM24301.1 - 0.0043 17.6 0.3 4.7 7.9 0.0 3.1 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Exo_endo_phos PF03372.23 KFM24303.1 - 3e-15 56.4 0.0 5.8e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 KFM24303.1 - 1.2e-10 41.3 2.0 1.2e-10 41.3 2.0 2.1 2 0 0 2 2 2 1 GRF zinc finger Ank_2 PF12796.7 KFM24304.1 - 9.2e-35 119.1 2.1 3.8e-15 56.2 0.0 4.2 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM24304.1 - 1.2e-28 99.1 5.3 8.6e-09 35.8 0.0 5.5 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFM24304.1 - 8.3e-25 86.5 15.5 1.9e-09 37.6 0.0 5.9 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM24304.1 - 6.4e-22 75.3 7.0 0.00031 21.0 0.0 7.3 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 KFM24304.1 - 2.7e-20 71.8 17.0 7.7e-05 23.0 0.5 6.8 6 0 0 6 6 6 5 Ankyrin repeat NUDIX PF00293.28 KFM24305.1 - 0.02 14.9 0.8 0.3 11.1 0.8 2.2 1 1 0 1 1 1 0 NUDIX domain CoA_transf_3 PF02515.17 KFM24307.1 - 7.4e-81 272.1 0.0 2e-80 270.7 0.0 1.5 1 1 0 1 1 1 1 CoA-transferase family III Glyco_hydro_99 PF16317.5 KFM24308.1 - 0.067 12.3 0.6 0.079 12.1 0.6 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 99 ParBc PF02195.18 KFM24310.1 - 2.6e-16 59.7 0.1 3.4e-16 59.3 0.1 1.1 1 0 0 1 1 1 1 ParB-like nuclease domain ABM PF03992.16 KFM24311.1 - 0.036 14.2 0.0 0.064 13.4 0.0 1.4 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase zf-U1 PF06220.12 KFM24312.1 - 8.1e-12 44.7 0.2 1.7e-11 43.6 0.2 1.6 1 0 0 1 1 1 1 U1 zinc finger OCRE PF17780.1 KFM24312.1 - 0.013 15.5 2.7 0.021 14.9 2.7 1.3 1 0 0 1 1 1 0 OCRE domain ADH_zinc_N PF00107.26 KFM24314.1 - 1.4e-18 67.1 1.3 2.2e-18 66.5 1.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFM24314.1 - 1.5e-08 35.7 0.1 3.1e-08 34.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFM24314.1 - 2.1e-06 27.6 0.0 1.1e-05 25.2 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KFM24314.1 - 5.9e-05 22.9 0.0 0.00013 21.8 0.0 1.6 1 1 0 1 1 1 1 N-terminal domain of oxidoreductase RMI1_C PF16099.5 KFM24315.1 - 0.00044 20.1 0.0 0.00051 19.9 0.0 1.1 1 0 0 1 1 1 1 Recq-mediated genome instability protein 1, C-terminal OB-fold GTP_EFTU PF00009.27 KFM24316.1 - 2.2e-31 109.0 0.0 1.1e-30 106.7 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KFM24316.1 - 5.9e-21 74.6 0.1 1.4e-20 73.3 0.1 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D4 PF14578.6 KFM24316.1 - 3.3e-14 52.5 0.0 9.2e-14 51.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 tRNA_bind PF01588.20 KFM24316.1 - 1.1e-13 51.1 0.3 4.2e-13 49.2 0.3 2.0 1 0 0 1 1 1 1 Putative tRNA binding domain GTP_EFTU_D2 PF03144.25 KFM24316.1 - 2.6e-12 47.0 2.5 7.8e-09 35.8 0.3 3.3 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFM24316.1 - 8e-06 25.9 0.2 0.00022 21.3 0.0 3.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase TniB PF05621.11 KFM24316.1 - 0.036 13.5 0.0 0.1 12.0 0.0 1.7 1 0 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.6 KFM24316.1 - 0.28 11.6 0.0 0.28 11.6 0.0 3.1 2 0 0 2 2 2 0 AAA ATPase domain TPT PF03151.16 KFM24317.1 - 8.3e-24 84.4 19.4 1e-23 84.1 19.4 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KFM24317.1 - 2.4e-08 33.6 18.1 3e-08 33.2 18.1 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KFM24317.1 - 1.8 8.7 35.9 0.62 10.2 15.3 2.3 2 0 0 2 2 2 0 EamA-like transporter family Ribosomal_L13 PF00572.18 KFM24318.1 - 4.1e-11 43.2 0.1 5.1e-09 36.4 0.0 2.5 1 1 0 1 1 1 1 Ribosomal protein L13 Band_7 PF01145.25 KFM24319.1 - 8.4e-25 87.8 0.7 1.5e-24 87.0 0.7 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family DNA_ligase_A_M PF01068.21 KFM24321.1 - 7.6e-43 146.5 0.0 1.1e-42 146.0 0.0 1.2 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KFM24321.1 - 1.4e-39 136.2 0.0 2.6e-39 135.3 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KFM24321.1 - 3.6e-23 82.0 0.0 9e-23 80.8 0.0 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region Peptidase_M50 PF02163.22 KFM24322.1 - 1.9e-62 210.8 0.0 2.2e-62 210.6 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M50 PDZ_6 PF17820.1 KFM24322.1 - 3.2e-06 26.9 0.6 7.5e-06 25.7 0.6 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFM24322.1 - 0.00027 21.2 0.1 0.0025 18.1 0.0 2.4 3 0 0 3 3 3 1 PDZ domain PDZ_2 PF13180.6 KFM24322.1 - 0.00057 20.2 0.0 0.0011 19.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain AdoHcyase PF05221.17 KFM24323.1 - 2.2e-141 470.3 0.0 2.5e-141 470.1 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 KFM24323.1 - 2e-81 271.8 0.9 2.8e-81 271.3 0.9 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KFM24323.1 - 2.3e-09 36.9 0.2 3.9e-09 36.1 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KFM24323.1 - 0.00068 19.2 0.2 0.0013 18.4 0.2 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain XdhC_C PF13478.6 KFM24323.1 - 0.002 18.6 0.1 0.021 15.3 0.0 2.2 2 0 0 2 2 2 1 XdhC Rossmann domain Shikimate_DH PF01488.20 KFM24323.1 - 0.0021 18.1 0.2 0.0046 17.0 0.2 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KFM24323.1 - 0.0024 18.4 0.3 0.007 16.9 0.3 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 KFM24323.1 - 0.015 15.7 0.1 0.033 14.6 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.19 KFM24323.1 - 0.017 14.4 0.5 0.063 12.6 0.5 1.8 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TrkA_N PF02254.18 KFM24323.1 - 0.028 14.7 0.4 0.15 12.3 0.4 2.1 1 1 0 1 1 1 0 TrkA-N domain Urocanase PF01175.18 KFM24323.1 - 0.17 11.5 0.2 0.29 10.8 0.2 1.3 1 0 0 1 1 1 0 Urocanase Rossmann-like domain TMEM107 PF14995.6 KFM24323.1 - 0.89 10.0 5.0 3.6 8.0 0.1 2.4 2 0 0 2 2 2 0 Transmembrane protein ACPS PF01648.20 KFM24325.1 - 2.2e-11 43.9 0.1 4.1e-11 43.0 0.0 1.4 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily cNMP_binding PF00027.29 KFM24326.1 - 2.9e-34 117.0 0.0 1e-14 54.3 0.0 3.8 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Patatin PF01734.22 KFM24326.1 - 3.4e-18 66.6 3.3 4.5e-17 62.9 3.3 2.5 1 1 0 1 1 1 1 Patatin-like phospholipase DEAD PF00270.29 KFM24327.1 - 5.1e-44 150.1 0.0 8.5e-44 149.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM24327.1 - 4.4e-19 68.9 0.0 2.6e-18 66.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KFM24327.1 - 1.8e-13 50.5 0.1 3.6e-13 49.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KFM24327.1 - 3.6e-06 27.1 0.0 8.3e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KFM24327.1 - 0.46 9.7 0.0 0.46 9.7 0.0 1.8 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase LRR_4 PF12799.7 KFM24328.1 - 4.3e-07 30.1 0.0 0.67 10.5 0.1 5.6 6 2 1 7 7 7 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFM24328.1 - 0.00028 20.6 5.3 2.2 8.1 0.0 5.4 3 2 1 4 4 4 3 Leucine rich repeat F-box-like PF12937.7 KFM24328.1 - 0.057 13.3 0.4 0.21 11.5 0.4 2.0 1 0 0 1 1 1 0 F-box-like F-box_5 PF18511.1 KFM24328.1 - 0.058 13.0 1.0 0.12 12.0 1.0 1.4 1 0 0 1 1 1 0 F-box HSP70 PF00012.20 KFM24329.1 - 7.6e-254 843.4 3.1 8.6e-254 843.2 3.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFM24329.1 - 1.1e-16 60.6 0.4 1.5e-14 53.6 0.4 2.5 1 1 0 1 1 1 1 MreB/Mbl protein FtsA PF14450.6 KFM24329.1 - 0.002 18.5 0.4 0.4 11.1 0.0 3.2 3 1 0 3 3 3 1 Cell division protein FtsA StbA PF06406.11 KFM24329.1 - 0.005 16.1 0.1 0.022 14.0 0.0 2.0 3 0 0 3 3 3 1 StbA protein Hydantoinase_A PF01968.18 KFM24329.1 - 0.0054 16.0 1.3 1.2 8.4 0.1 3.1 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase DP PF08781.10 KFM24329.1 - 0.16 11.8 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 Transcription factor DP Archease PF01951.16 KFM24332.1 - 4.1e-25 88.6 0.1 4.4e-25 88.5 0.1 1.0 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) S-AdoMet_synt_C PF02773.16 KFM24334.1 - 2.2e-59 199.4 0.0 4e-59 198.5 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 KFM24334.1 - 1.2e-46 157.8 0.0 3.3e-46 156.4 0.0 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 KFM24334.1 - 3e-43 146.5 0.4 6.3e-43 145.5 0.4 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Cation_ATPase_C PF00689.21 KFM24335.1 - 2.3e-48 164.3 1.4 4.2e-48 163.5 1.4 1.5 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KFM24335.1 - 9.4e-47 158.9 2.2 2.2e-46 157.7 0.2 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 KFM24335.1 - 4.4e-17 61.5 0.2 1.3e-16 60.1 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KFM24335.1 - 3.7e-15 55.8 0.0 7.2e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFM24335.1 - 1.8e-14 54.5 14.3 5.7e-13 49.6 14.3 3.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFM24335.1 - 2.8e-05 24.6 0.2 9.7e-05 22.9 0.2 2.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KFM24335.1 - 0.00014 21.7 1.2 0.00014 21.7 1.2 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2545 PF10810.8 KFM24335.1 - 0.0086 16.2 0.9 0.034 14.3 0.9 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2545) Polysacc_deac_2 PF04748.13 KFM24335.1 - 0.095 11.9 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase MoeA_N PF03453.17 KFM24335.1 - 0.19 11.5 3.2 0.096 12.4 0.2 2.0 2 0 0 2 2 2 0 MoeA N-terminal region (domain I and II) LSM PF01423.22 KFM24337.1 - 9e-15 54.1 0.0 1.3e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KFM24337.1 - 0.0068 16.5 0.0 0.0099 16.0 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain AIG1 PF04548.16 KFM24338.1 - 9.1e-25 87.2 0.0 1.3e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 KFM24338.1 - 3.9e-09 36.6 0.0 6.7e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFM24338.1 - 0.0019 18.2 0.1 0.0054 16.7 0.1 1.7 1 1 1 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KFM24338.1 - 0.017 15.5 1.8 0.022 15.1 0.3 2.0 2 1 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 KFM24338.1 - 0.02 15.3 0.0 0.038 14.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.18 KFM24338.1 - 0.026 13.8 0.0 0.044 13.1 0.0 1.4 1 1 0 1 1 1 0 Septin DUF815 PF05673.13 KFM24338.1 - 0.058 12.5 0.2 0.29 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Dynamin_N PF00350.23 KFM24338.1 - 0.21 11.7 0.7 0.85 9.7 0.2 2.0 1 1 1 2 2 2 0 Dynamin family Ank_4 PF13637.6 KFM24339.1 - 6.2e-18 64.9 0.1 8.7e-10 38.9 0.0 2.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFM24339.1 - 1.7e-15 56.9 0.5 8e-11 42.0 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM24339.1 - 4.3e-12 46.5 0.0 7.6e-05 23.2 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFM24339.1 - 7.6e-12 44.3 0.1 0.00018 21.7 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KFM24339.1 - 5.9e-10 39.1 0.6 0.00036 20.8 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat STI1 PF17830.1 KFM24339.1 - 1.4e-05 24.9 8.0 0.0049 16.8 0.0 3.2 2 1 0 2 2 2 2 STI1 domain Fer2 PF00111.27 KFM24340.1 - 1.2e-14 54.0 0.3 2.3e-14 53.1 0.3 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF4512 PF14975.6 KFM24340.1 - 0.069 13.9 0.2 0.5 11.2 0.0 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4512) HNH_5 PF14279.6 KFM24341.1 - 3.6e-16 58.7 1.0 5.6e-16 58.1 1.0 1.3 1 0 0 1 1 1 1 HNH endonuclease HNH PF01844.23 KFM24341.1 - 1.5e-12 47.4 0.6 2.4e-12 46.8 0.6 1.3 1 0 0 1 1 1 1 HNH endonuclease HNH_4 PF13395.6 KFM24341.1 - 5.1e-06 26.3 0.0 9.3e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease Endonuclease_7 PF02945.15 KFM24341.1 - 0.12 12.3 2.5 0.32 11.0 2.5 1.7 1 1 0 1 1 1 0 Recombination endonuclease VII AMPK1_CBM PF16561.5 KFM24342.1 - 2.4e-16 59.7 0.0 3.5e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CDC24_OB3 PF17244.2 KFM24343.1 - 0.02 14.6 0.0 0.02 14.6 0.0 1.1 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 3 RINGv PF12906.7 KFM24343.1 - 0.034 14.3 2.4 0.049 13.8 2.4 1.3 1 0 0 1 1 1 0 RING-variant domain FHA PF00498.26 KFM24344.1 - 2.9e-12 46.8 0.0 4.6e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 FHA domain PHD PF00628.29 KFM24344.1 - 2.9e-10 39.9 6.2 4.5e-10 39.3 6.2 1.3 1 0 0 1 1 1 1 PHD-finger Yop-YscD_cpl PF16697.5 KFM24344.1 - 1.7e-09 37.9 0.0 4.7e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain C1_1 PF00130.22 KFM24344.1 - 0.034 14.0 2.1 0.067 13.1 2.1 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 KFM24344.1 - 0.051 13.1 2.3 0.086 12.4 2.3 1.4 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.6 KFM24344.1 - 0.1 12.6 2.2 0.19 11.7 2.2 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 C1_2 PF03107.16 KFM24344.1 - 0.35 11.2 3.6 0.64 10.4 3.6 1.4 1 0 0 1 1 1 0 C1 domain 4HBT PF03061.22 KFM24345.1 - 1.3e-27 95.9 5.8 2.6e-14 53.3 0.3 2.7 3 0 0 3 3 3 2 Thioesterase superfamily ACPS PF01648.20 KFM24347.1 - 3.7e-12 46.4 0.0 4.8e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily PRA1 PF03208.19 KFM24348.1 - 6.8e-35 119.8 1.7 8.3e-35 119.5 1.7 1.1 1 0 0 1 1 1 1 PRA1 family protein TraL PF07178.11 KFM24348.1 - 0.034 14.6 3.8 2.9 8.4 0.1 2.2 2 0 0 2 2 2 0 TraL protein Man-6-P_recep PF02157.15 KFM24348.1 - 0.1 11.7 0.1 0.13 11.3 0.1 1.1 1 0 0 1 1 1 0 Mannose-6-phosphate receptor DUF3341 PF11821.8 KFM24348.1 - 0.18 11.4 3.8 0.47 10.1 3.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3341) PG_binding_1 PF01471.18 KFM24350.1 - 9.2e-17 61.0 0.0 3e-08 33.8 0.0 2.3 2 0 0 2 2 2 2 Putative peptidoglycan binding domain Ufm1 PF03671.14 KFM24351.1 - 2e-40 136.7 0.0 4.6e-40 135.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein SBP_bac_11 PF13531.6 KFM24351.1 - 2e-33 116.1 0.1 3.3e-33 115.4 0.1 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 KFM24351.1 - 1.9e-06 28.1 0.1 1.4e-05 25.2 0.1 2.1 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein PBP_like PF12727.7 KFM24351.1 - 0.0084 15.2 0.1 0.023 13.8 0.0 1.6 1 1 0 1 1 1 1 PBP superfamily domain tRNA-synt_2 PF00152.20 KFM24352.1 - 6.1e-62 209.5 0.0 4.8e-58 196.7 0.0 3.0 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KFM24352.1 - 4.3e-16 58.7 0.1 7.6e-16 57.9 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KFM24352.1 - 0.00017 21.2 0.1 0.71 9.3 0.0 2.5 2 1 0 3 3 3 2 tRNA synthetases class II core domain (F) adh_short PF00106.25 KFM24353.1 - 1.7e-33 115.7 0.7 2.4e-33 115.2 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM24353.1 - 8.4e-24 84.4 0.5 1.1e-23 84.0 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM24353.1 - 3.7e-07 30.2 0.6 5e-07 29.8 0.6 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFM24353.1 - 0.0031 17.0 0.0 0.0042 16.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KFM24353.1 - 0.049 13.9 0.1 0.074 13.3 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 KFM24353.1 - 0.051 14.2 0.1 0.11 13.1 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent UBA PF00627.31 KFM24354.1 - 0.035 14.0 0.1 0.1 12.5 0.0 1.8 2 0 0 2 2 2 0 UBA/TS-N domain Late_protein_L2 PF00513.18 KFM24354.1 - 0.14 11.1 0.5 0.18 10.8 0.5 1.1 1 0 0 1 1 1 0 Late Protein L2 Usp PF00582.26 KFM24356.1 - 1.4e-08 35.4 0.0 4.3e-06 27.3 0.0 3.1 2 2 0 2 2 2 2 Universal stress protein family PKcGMP_CC PF16808.5 KFM24356.1 - 0.018 14.9 1.5 0.037 13.9 1.5 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SlyX PF04102.12 KFM24356.1 - 4.1 8.1 7.1 14 6.4 7.3 1.9 2 0 0 2 2 2 0 SlyX Methyltransf_25 PF13649.6 KFM24357.1 - 1e-15 58.2 0.0 2.2e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFM24357.1 - 1e-14 54.9 0.0 2e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM24357.1 - 2.9e-14 53.2 0.0 4.6e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM24357.1 - 1.3e-08 35.5 0.0 5.6e-08 33.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFM24357.1 - 8.2e-07 28.6 0.0 9.5e-06 25.1 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KFM24357.1 - 5.7e-05 23.0 0.0 0.0004 20.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.12 KFM24357.1 - 0.00068 19.5 0.0 0.0034 17.2 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF938) Actin PF00022.19 KFM24358.1 - 3.8e-81 272.8 0.0 1.6e-36 125.8 0.0 3.0 2 1 1 3 3 3 3 Actin MreB_Mbl PF06723.13 KFM24358.1 - 0.0012 17.7 0.0 0.6 8.9 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein Prenyltransf PF01255.19 KFM24359.1 - 2.5e-60 203.8 0.0 3.6e-60 203.3 0.0 1.2 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Profilin PF00235.19 KFM24361.1 - 1.6e-05 25.2 0.0 2.1e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Profilin VHL PF01847.16 KFM24362.1 - 3.5e-11 42.9 0.0 6.6e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 VHL beta domain Glyco_hydro_1 PF00232.18 KFM24363.1 - 4.5e-65 219.8 0.7 3.3e-64 217.0 0.7 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 TPM_phosphatase PF04536.14 KFM24363.1 - 8.5e-14 51.8 0.0 1.6e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 TPM domain zf-RING_2 PF13639.6 KFM24363.1 - 2.1e-10 40.8 6.2 6.7e-09 35.9 3.5 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 KFM24363.1 - 1.1e-09 38.0 3.7 6.6e-09 35.5 1.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFM24363.1 - 1.9e-08 34.0 9.0 1e-07 31.6 5.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM24363.1 - 4.4e-08 32.9 5.5 1.7e-07 31.0 3.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFM24363.1 - 4e-07 30.2 1.4 4e-07 30.2 1.4 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger domain Cellulase PF00150.18 KFM24363.1 - 1.2e-06 28.1 0.0 0.00084 18.9 0.0 3.0 4 0 0 4 4 4 1 Cellulase (glycosyl hydrolase family 5) zf-RING_5 PF14634.6 KFM24363.1 - 1.3e-06 28.2 1.9 1.3e-06 28.2 1.9 2.2 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFM24363.1 - 3.3e-06 26.8 7.3 4.8e-06 26.3 2.9 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KFM24363.1 - 4.4e-06 26.6 15.0 2.1e-05 24.5 4.0 3.3 2 1 1 3 3 3 2 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KFM24363.1 - 0.00012 22.2 3.4 0.00012 22.2 3.4 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING MOLO1 PF17175.4 KFM24363.1 - 0.00036 20.7 0.0 0.00066 19.8 0.0 1.4 1 0 0 1 1 1 1 Modulator of levamisole receptor-1 zf-ANAPC11 PF12861.7 KFM24363.1 - 0.0004 20.4 0.3 0.0013 18.7 0.3 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Glyco_hydro_10 PF00331.20 KFM24363.1 - 0.0028 16.9 0.0 0.0054 15.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 zf-RING_4 PF14570.6 KFM24363.1 - 0.0088 15.8 1.2 0.0088 15.8 1.2 2.5 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain Glyco_hydro_cc PF11790.8 KFM24363.1 - 0.056 13.0 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core DUF1272 PF06906.11 KFM24363.1 - 0.19 11.8 2.3 0.49 10.5 2.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_10 PF16685.5 KFM24363.1 - 0.35 11.0 1.8 1 9.5 1.8 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 KFM24363.1 - 1.2 9.0 3.2 13 5.7 0.1 3.1 3 0 0 3 3 3 0 RING-like zinc finger Mito_carr PF00153.27 KFM24364.1 - 1e-40 137.5 4.6 9.1e-18 64.0 0.3 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein GCFC PF07842.12 KFM24365.1 - 1e-07 31.9 0.0 4.1e-07 29.9 0.0 1.9 1 1 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein Pkinase PF00069.25 KFM24366.1 - 3.5e-31 108.5 0.0 4.8e-30 104.8 0.0 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM24366.1 - 2.1e-11 43.6 0.0 6.7e-10 38.7 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM24366.1 - 0.0027 17.1 0.0 0.0038 16.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFM24366.1 - 0.0089 15.4 0.0 0.051 12.9 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFM24366.1 - 0.013 15.5 0.9 0.079 12.9 0.1 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family Aldo_ket_red PF00248.21 KFM24368.1 - 3.3e-36 125.0 0.0 1.2e-34 119.9 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family ShK PF01549.24 KFM24368.1 - 0.26 11.8 1.7 0.52 10.9 1.7 1.5 1 0 0 1 1 1 0 ShK domain-like Ribosomal_L31 PF01197.18 KFM24369.1 - 7e-07 29.4 0.0 8.6e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L31 HTH_33 PF13592.6 KFM24369.1 - 0.079 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn helix CSD PF00313.22 KFM24370.1 - 8.9e-26 89.5 0.2 1.1e-25 89.2 0.2 1.1 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 KFM24370.1 - 0.00021 20.9 0.1 0.00045 19.9 0.1 1.5 1 0 0 1 1 1 1 Ribonuclease B OB domain Aminotran_1_2 PF00155.21 KFM24371.1 - 2.9e-46 158.3 0.0 1.2e-39 136.5 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class I and II ALMT PF11744.8 KFM24372.1 - 9e-12 44.6 1.3 1.6e-11 43.7 1.3 1.3 1 0 0 1 1 1 1 Aluminium activated malate transporter FUSC_2 PF13515.6 KFM24372.1 - 1.7e-09 37.8 5.8 1.7e-09 37.8 5.8 2.1 1 1 0 1 1 1 1 Fusaric acid resistance protein-like FUSC PF04632.12 KFM24372.1 - 6.7e-09 34.9 25.5 2.2e-08 33.1 25.5 1.9 1 1 0 1 1 1 1 Fusaric acid resistance protein family ArAE_2 PF10334.9 KFM24372.1 - 0.011 15.6 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Aromatic acid exporter family member 2 RRM_1 PF00076.22 KFM24373.1 - 8.9e-14 51.1 0.0 1.6e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4140 PF13600.6 KFM24373.1 - 0.21 12.1 0.7 0.42 11.1 0.7 1.5 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) AAA PF00004.29 KFM24375.1 - 1.6e-31 109.5 0.0 3e-31 108.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) zf-HC5HC2H PF13771.6 KFM24375.1 - 1.6e-07 31.4 9.5 3.4e-07 30.4 9.5 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain TPM_phosphatase PF04536.14 KFM24375.1 - 5.7e-06 26.5 0.0 9e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 TPM domain AAA_lid_3 PF17862.1 KFM24375.1 - 7.7e-05 22.4 2.9 0.00027 20.7 2.9 1.9 1 0 0 1 1 1 1 AAA+ lid domain zf-HC5HC2H_2 PF13832.6 KFM24375.1 - 0.0006 19.9 8.7 0.0014 18.8 8.7 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain Far-17a_AIG1 PF04750.14 KFM24376.1 - 1.7e-18 66.7 2.5 2.1e-18 66.4 2.5 1.1 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein SBP PF03110.14 KFM24377.1 - 3e-30 104.3 4.1 4.5e-30 103.8 4.1 1.3 1 0 0 1 1 1 1 SBP domain ABC_tran PF00005.27 KFM24379.1 - 4.9e-24 85.4 0.0 7.6e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KFM24379.1 - 5.5e-08 33.0 0.2 0.00057 19.8 0.1 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KFM24379.1 - 0.00054 20.4 2.6 0.00094 19.6 0.8 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 KFM24379.1 - 0.0011 18.7 2.5 0.0021 17.8 0.3 2.3 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 KFM24379.1 - 0.0012 18.8 0.1 0.0028 17.6 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 KFM24379.1 - 0.0016 17.9 0.0 0.062 12.7 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 KFM24379.1 - 0.0019 17.8 0.7 0.0019 17.8 0.7 2.1 2 2 0 2 2 2 1 AAA domain CbiA PF01656.23 KFM24379.1 - 0.0067 16.5 0.0 1 9.4 0.0 2.3 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_29 PF13555.6 KFM24379.1 - 0.024 14.4 0.2 0.048 13.4 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KFM24379.1 - 0.027 15.0 0.0 0.061 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KFM24379.1 - 0.028 14.7 1.4 0.38 11.0 0.1 2.8 3 1 0 3 3 3 0 AAA domain cobW PF02492.19 KFM24379.1 - 0.067 12.8 0.7 0.11 12.0 0.7 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KFM24379.1 - 0.11 12.6 1.2 0.5 10.5 1.2 2.3 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 KFM24379.1 - 0.13 12.2 0.1 0.23 11.4 0.1 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain NACHT PF05729.12 KFM24379.1 - 0.21 11.5 0.1 0.21 11.5 0.1 2.2 2 1 0 2 2 2 0 NACHT domain IstB_IS21 PF01695.17 KFM24379.1 - 0.22 11.2 0.4 22 4.7 0.1 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_5 PF07728.14 KFM24379.1 - 0.28 11.2 0.9 4.7 7.2 0.3 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KFM24379.1 - 0.31 11.3 1.3 0.65 10.2 1.3 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KFM24379.1 - 0.35 11.3 1.3 0.86 10.0 0.6 2.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UAA PF08449.11 KFM24382.1 - 3.2e-52 177.6 1.7 3.9e-52 177.3 1.7 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KFM24382.1 - 0.00015 21.9 19.5 0.017 15.3 11.3 2.3 2 0 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 KFM24382.1 - 0.39 9.6 1.5 3.7 6.4 0.5 2.1 2 0 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like Mito_carr PF00153.27 KFM24383.1 - 2.6e-63 210.0 4.0 2.9e-22 78.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.32 KFM24384.1 - 5.7e-50 166.2 20.2 3.5e-07 30.8 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM24384.1 - 1.2e-07 32.0 0.8 0.49 10.7 0.0 4.4 1 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KFM24384.1 - 0.0028 16.3 0.2 0.38 9.2 0.2 2.3 2 0 0 2 2 2 2 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 KFM24384.1 - 0.016 14.2 0.0 9.2 5.1 0.0 3.5 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KFM24384.1 - 0.049 12.3 8.3 2.2 6.8 0.1 4.4 2 2 3 5 5 5 0 Nucleoporin Nup120/160 WD40_like PF17005.5 KFM24384.1 - 0.27 10.5 0.0 8.6 5.6 0.0 2.2 2 1 0 2 2 2 0 WD40-like domain zf-trcl PF13451.6 KFM24385.1 - 0.018 14.9 0.2 0.025 14.5 0.2 1.2 1 0 0 1 1 1 0 Probable zinc-ribbon domain Phage_holin_3_6 PF07332.11 KFM24385.1 - 0.55 10.3 8.0 0.83 9.7 8.0 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Rieske PF00355.26 KFM24386.1 - 6.9e-19 67.6 0.0 1.3e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain PaO PF08417.12 KFM24386.1 - 8.9e-16 57.8 0.0 1.6e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Pheophorbide a oxygenase NDUF_B12 PF08122.12 KFM24387.1 - 1.4e-09 37.9 0.2 1.7e-09 37.6 0.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family RIC3 PF15361.6 KFM24387.1 - 0.087 13.2 0.0 0.087 13.2 0.0 1.1 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Proteasome PF00227.26 KFM24388.1 - 5.4e-32 110.8 0.0 1.5e-31 109.4 0.0 1.7 1 1 0 1 1 1 1 Proteasome subunit NUFIP1 PF10453.9 KFM24389.1 - 1.6e-08 34.2 8.0 3.8e-08 33.0 8.0 1.6 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) YlqD PF11068.8 KFM24390.1 - 0.14 12.5 15.5 0.056 13.8 7.7 2.2 1 1 1 2 2 2 0 YlqD protein Helicase_PWI PF18149.1 KFM24390.1 - 0.28 11.4 4.8 0.14 12.3 0.9 2.2 2 0 0 2 2 2 0 N-terminal helicase PWI domain Exonuc_VII_L PF02601.15 KFM24390.1 - 0.65 9.5 10.1 0.85 9.1 10.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Tho2 PF11262.8 KFM24390.1 - 8.3 5.5 7.1 5.5 6.1 5.5 1.4 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 V_ATPase_I PF01496.19 KFM24390.1 - 8.9 4.1 5.2 10 3.9 5.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Kinesin PF00225.23 KFM24391.1 - 1.3e-86 290.6 0.4 2.2e-84 283.2 0.4 2.2 1 1 0 1 1 1 1 Kinesin motor domain Peptidase_M24 PF00557.24 KFM24391.1 - 3.1e-53 180.6 0.0 7.8e-53 179.3 0.0 1.8 1 0 0 1 1 1 1 Metallopeptidase family M24 Microtub_bd PF16796.5 KFM24391.1 - 6.9e-38 129.9 0.0 1.5e-37 128.8 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding AMP_N PF05195.16 KFM24391.1 - 1.9e-26 92.2 0.0 8.5e-26 90.1 0.0 2.0 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain FERM_M PF00373.18 KFM24391.1 - 5.5e-12 46.1 0.0 1.9e-11 44.4 0.0 2.1 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.10 KFM24391.1 - 2.6e-09 36.9 0.0 1.6e-08 34.4 0.0 2.2 2 0 0 2 2 2 1 FERM N-terminal domain MyTH4 PF00784.17 KFM24391.1 - 0.0018 18.8 0.0 0.004 17.6 0.0 1.7 1 0 0 1 1 1 1 MyTH4 domain FERM_f0 PF16511.5 KFM24391.1 - 0.0024 18.1 0.1 4.3 7.7 0.1 2.5 2 0 0 2 2 2 2 N-terminal or F0 domain of Talin-head FERM Golgin_A5 PF09787.9 KFM24391.1 - 1.7 8.1 11.0 0.96 8.9 7.6 2.0 2 0 0 2 2 2 0 Golgin subfamily A member 5 FAM184 PF15665.5 KFM24391.1 - 1.9 8.2 9.5 5.7 6.7 9.5 1.8 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Spc7 PF08317.11 KFM24391.1 - 2.8 6.7 9.7 6 5.7 9.7 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein CTP_transf_like PF01467.26 KFM24393.1 - 7.3e-05 23.0 0.0 0.00029 21.0 0.0 2.0 1 1 0 1 1 1 1 Cytidylyltransferase-like CinA PF02464.17 KFM24393.1 - 0.093 12.3 0.3 0.15 11.6 0.3 1.3 1 0 0 1 1 1 0 Competence-damaged protein Amidinotransf PF02274.17 KFM24395.1 - 6.8e-09 35.3 0.0 0.0003 20.0 0.0 2.1 1 1 1 2 2 2 2 Amidinotransferase Gcd10p PF04189.13 KFM24395.1 - 0.18 10.9 0.0 0.25 10.4 0.0 1.1 1 0 0 1 1 1 0 Gcd10p family LPMO_10 PF03067.15 KFM24396.1 - 7.7e-21 75.6 1.2 1e-20 75.2 1.2 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading CBM_14 PF01607.24 KFM24396.1 - 5.7e-12 45.6 2.6 2e-11 43.8 2.6 2.0 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain DUF2001 PF09393.10 KFM24396.1 - 0.21 11.6 0.0 0.32 11.0 0.0 1.1 1 0 0 1 1 1 0 Phage tail tube protein LPMO_10 PF03067.15 KFM24397.1 - 1.2e-19 71.8 0.2 1.5e-19 71.5 0.2 1.1 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading DUF1964 PF09244.10 KFM24397.1 - 0.0016 18.8 0.1 0.0036 17.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1964) He_PIG PF05345.12 KFM24397.1 - 0.043 14.0 0.2 1 9.6 0.2 2.5 2 0 0 2 2 2 0 Putative Ig domain Egh16-like PF11327.8 KFM24397.1 - 0.076 13.4 0.1 0.11 12.9 0.1 1.3 1 0 0 1 1 1 0 Egh16-like virulence factor NUDIX PF00293.28 KFM24398.1 - 6.3e-05 23.0 0.1 9.8e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain Ish1 PF10281.9 KFM24398.1 - 0.034 14.4 0.0 0.054 13.8 0.0 1.3 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein NMT PF01233.19 KFM24399.1 - 1.9e-74 248.8 0.0 4.1e-74 247.8 0.0 1.6 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.15 KFM24399.1 - 2e-68 230.0 0.0 2.9e-68 229.5 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_1 PF00583.25 KFM24399.1 - 0.00024 21.3 0.0 0.00041 20.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KFM24399.1 - 0.018 15.2 0.0 0.056 13.5 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Pkinase PF00069.25 KFM24400.1 - 1.7e-53 181.7 0.0 2.3e-53 181.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM24400.1 - 1e-35 123.3 0.0 1.4e-35 122.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFM24400.1 - 0.0039 17.1 2.8 0.01 15.8 0.1 2.7 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFM24400.1 - 0.0075 15.1 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFM24400.1 - 0.048 13.0 0.0 0.12 11.7 0.0 1.5 1 1 0 1 1 1 0 Kinase-like bZIP_2 PF07716.15 KFM24402.1 - 9.2e-06 25.6 8.0 2.1e-05 24.5 8.0 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KFM24402.1 - 3.6e-05 23.8 6.3 9.3e-05 22.5 6.3 1.6 1 0 0 1 1 1 1 bZIP transcription factor LTXXQ PF07813.12 KFM24402.1 - 0.0074 17.0 8.2 0.95 10.2 0.1 2.6 2 0 0 2 2 2 2 LTXXQ motif family protein Tmemb_cc2 PF10267.9 KFM24402.1 - 0.02 14.0 0.5 0.032 13.4 0.5 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein CENP-F_leu_zip PF10473.9 KFM24402.1 - 0.024 14.7 3.9 0.052 13.6 3.9 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PRKG1_interact PF15898.5 KFM24402.1 - 0.54 11.2 5.9 0.16 12.9 2.6 1.8 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain NRBF2 PF08961.10 KFM24402.1 - 1.4 8.5 4.8 2.1 7.9 4.2 1.6 1 1 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator TPT PF03151.16 KFM24403.1 - 1.1e-14 54.5 10.9 1.4e-14 54.2 10.9 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KFM24403.1 - 1e-05 24.9 9.1 1.3e-05 24.6 9.1 1.2 1 0 0 1 1 1 1 UAA transporter family GDPD PF03009.17 KFM24405.1 - 2.6e-36 125.7 0.0 8.3e-22 78.1 0.0 2.2 1 1 1 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family DUF3754 PF12576.8 KFM24405.1 - 1.7e-11 44.2 0.1 3.2e-11 43.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3754) Ribonuc_red_sm PF00268.21 KFM24406.1 - 1.7e-107 359.1 0.0 2e-107 358.8 0.0 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DNA_mis_repair PF01119.19 KFM24407.1 - 3.8e-17 62.1 0.0 6.4e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.11 KFM24407.1 - 3.7e-15 56.0 0.1 9.2e-15 54.7 0.1 1.7 2 0 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.6 KFM24407.1 - 1.6e-13 50.7 0.0 3.5e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KFM24407.1 - 2.1e-06 28.2 0.0 4.5e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase End3 PF12761.7 KFM24407.1 - 0.064 13.4 0.0 0.23 11.6 0.0 1.8 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 UvdE PF03851.14 KFM24408.1 - 1.9e-64 217.6 0.0 2.6e-64 217.1 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE AP_endonuc_2 PF01261.24 KFM24408.1 - 0.00051 19.5 0.0 0.0015 18.0 0.0 1.8 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel Dynamin_N PF00350.23 KFM24409.1 - 1.8e-30 106.2 0.0 2.6e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KFM24409.1 - 4.8e-05 23.4 0.0 8.4e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Herpes_capsid PF06112.11 KFM24410.1 - 1.2 9.2 7.9 1.4 9.0 7.9 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DNA_ligase_A_M PF01068.21 KFM24411.1 - 9.9e-31 107.0 0.0 2e-30 106.0 0.0 1.5 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.15 KFM24411.1 - 6.1e-13 49.2 0.0 1.4e-12 48.1 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KFM24411.1 - 4.3e-08 33.6 0.0 8.5e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 RNA ligase DNA_ligase_A_N PF04675.14 KFM24411.1 - 1.5e-05 25.4 0.0 2.8e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus BRCT_2 PF16589.5 KFM24411.1 - 0.0016 18.8 0.0 0.0029 18.0 0.0 1.3 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KFM24411.1 - 0.0055 17.1 0.0 0.019 15.3 0.0 1.9 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Peptidase_S15 PF02129.18 KFM24411.1 - 0.095 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Glyco_transf_15 PF01793.16 KFM24412.1 - 1.9e-79 267.3 0.0 2.3e-79 267.0 0.0 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase GAF_2 PF13185.6 KFM24413.1 - 0.0028 17.9 0.1 0.01 16.1 0.1 1.9 1 1 0 1 1 1 1 GAF domain Vps35 PF03635.17 KFM24414.1 - 5.3e-210 699.7 0.0 7.1e-164 547.2 0.0 2.0 1 1 1 2 2 2 2 Vacuolar protein sorting-associated protein 35 TFIID_20kDa PF03847.13 KFM24415.1 - 1.9e-05 25.0 0.0 2.9e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Ion_trans PF00520.31 KFM24416.1 - 2.2e-06 27.1 37.9 0.0012 18.1 13.1 3.2 2 2 1 3 3 3 2 Ion transport protein DUF2755 PF10954.8 KFM24416.1 - 8.4e-06 25.6 1.9 0.046 13.6 0.1 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF2755) DUF4212 PF13937.6 KFM24416.1 - 0.0012 19.2 4.3 1.5 9.3 0.3 3.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4212) DUF2919 PF11143.8 KFM24416.1 - 0.014 15.7 26.5 0.13 12.6 9.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2919) DUF4306 PF14154.6 KFM24416.1 - 0.047 13.9 7.9 0.85 9.8 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4306) FliP PF00813.20 KFM24416.1 - 0.41 10.5 4.9 1.7 8.5 0.1 3.0 3 0 0 3 3 3 0 FliP family DUF1129 PF06570.11 KFM24416.1 - 8.4 5.8 10.5 8.5 5.8 0.3 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1129) Peptidase_C14 PF00656.22 KFM24418.1 - 5.5e-47 160.8 0.0 8.5e-47 160.2 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Ion_trans PF00520.31 KFM24418.1 - 3.4e-11 42.9 5.5 5.5e-11 42.2 5.4 1.4 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KFM24418.1 - 2e-06 26.7 1.9 8.6e-05 21.4 2.3 2.1 1 1 1 2 2 2 2 Polycystin cation channel NIF PF03031.18 KFM24419.1 - 1.4e-07 31.4 0.0 3.5e-07 30.1 0.0 1.7 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase DUF3662 PF12401.8 KFM24419.1 - 0.02 15.3 0.0 0.036 14.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2662) DUF2608 PF11019.8 KFM24419.1 - 0.2 11.1 0.0 0.31 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) Atg14 PF10186.9 KFM24420.1 - 0.044 12.9 0.0 0.062 12.4 0.0 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PNP_UDP_1 PF01048.20 KFM24423.1 - 3.2e-23 82.2 2.7 7e-23 81.1 2.7 1.5 1 1 0 1 1 1 1 Phosphorylase superfamily Brix PF04427.18 KFM24424.1 - 4.4e-30 105.2 0.8 6.4e-30 104.7 0.8 1.2 1 0 0 1 1 1 1 Brix domain Suf PF05843.14 KFM24424.1 - 0.013 15.5 0.4 0.02 14.9 0.4 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) VWA_2 PF13519.6 KFM24425.1 - 1.2e-09 38.7 0.0 3.8e-09 37.1 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KFM24425.1 - 7e-07 28.9 0.0 1.6e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein VWA_3 PF13768.6 KFM24425.1 - 0.025 14.5 0.0 0.059 13.3 0.0 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain Hydrolase_6 PF13344.6 KFM24426.1 - 4.9e-28 97.2 0.0 8.2e-28 96.5 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFM24426.1 - 3.7e-20 71.8 0.1 6.8e-20 70.9 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KFM24426.1 - 3.3e-07 30.8 0.0 0.0021 18.4 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KFM24426.1 - 4.1e-06 27.0 0.0 0.0038 17.3 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 KFM24426.1 - 0.0093 15.6 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase LSM PF01423.22 KFM24427.1 - 7.9e-22 76.7 0.2 9.7e-22 76.4 0.2 1.1 1 0 0 1 1 1 1 LSM domain vATP-synt_AC39 PF01992.16 KFM24428.1 - 4.9e-47 161.1 0.0 6e-47 160.8 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit vATP-synt_AC39 PF01992.16 KFM24429.1 - 1.5e-50 172.6 0.1 1.6e-50 172.5 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit AAA_25 PF13481.6 KFM24429.1 - 0.16 11.5 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain Copper-bind PF00127.20 KFM24430.1 - 6e-32 110.0 0.1 7.8e-32 109.7 0.1 1.2 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 KFM24430.1 - 1e-06 28.8 0.0 1.5e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Cupredoxin-like domain CorA PF01544.18 KFM24431.1 - 1.7e-07 30.9 4.2 0.00089 18.7 0.1 2.1 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Snapin_Pallidin PF14712.6 KFM24431.1 - 0.0022 18.4 0.9 0.011 16.1 0.1 2.2 2 0 0 2 2 2 1 Snapin/Pallidin DUF4692 PF15763.5 KFM24431.1 - 0.0045 17.5 0.1 0.0077 16.7 0.1 1.3 1 0 0 1 1 1 1 Regulator of human erythroid cell expansion (RHEX) AF-4 PF05110.13 KFM24431.1 - 0.053 11.6 1.5 0.063 11.4 1.5 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein IMUP PF15761.5 KFM24431.1 - 0.065 13.9 6.1 0.12 13.1 6.1 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein Baculo_PEP_C PF04513.12 KFM24431.1 - 0.3 11.1 3.1 1.6 8.8 0.2 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SR-25 PF10500.9 KFM24431.1 - 0.9 9.1 7.3 1.7 8.2 7.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Nup54 PF13874.6 KFM24431.1 - 8.7 6.5 6.5 27 4.8 0.8 2.7 1 1 0 2 2 2 0 Nucleoporin complex subunit 54 LRR_8 PF13855.6 KFM24432.1 - 1.1e-23 82.8 13.4 2.7e-07 30.3 0.1 5.8 3 2 2 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 KFM24432.1 - 2.1e-23 82.0 11.0 1.4e-05 25.3 0.9 7.2 2 1 7 10 10 10 9 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFM24432.1 - 1.5e-12 46.5 10.3 2.2 8.5 0.2 9.9 11 0 0 11 11 11 4 Leucine Rich repeat LRR_1 PF00560.33 KFM24432.1 - 7.9e-11 41.0 15.5 1 10.1 0.1 9.4 10 1 0 10 10 10 5 Leucine Rich Repeat AAA_25 PF13481.6 KFM24434.1 - 6e-16 58.6 0.0 1.2e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KFM24434.1 - 4.1e-14 52.5 0.5 1.6e-06 27.6 0.3 2.2 2 0 0 2 2 2 2 KaiC ChlI PF13541.6 KFM24434.1 - 1.7e-07 31.1 0.0 3.8e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase DnaB_C PF03796.15 KFM24434.1 - 2.5e-06 27.0 0.0 3.6e-05 23.2 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 KFM24434.1 - 9.5e-05 22.7 0.0 0.00025 21.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Rad51 PF08423.11 KFM24434.1 - 0.00047 19.5 0.1 0.00097 18.5 0.1 1.4 1 1 0 1 1 1 1 Rad51 AAA PF00004.29 KFM24434.1 - 0.00096 19.6 0.0 0.0018 18.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFM24434.1 - 0.0016 18.9 1.1 0.0039 17.6 0.9 1.9 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KFM24434.1 - 0.0017 18.3 0.0 0.0031 17.5 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Lon_C PF05362.13 KFM24434.1 - 0.0025 17.4 0.1 0.0048 16.5 0.1 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA_5 PF07728.14 KFM24434.1 - 0.004 17.2 0.0 0.0079 16.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 KFM24434.1 - 0.021 14.7 0.2 0.04 13.8 0.2 1.4 1 0 0 1 1 1 0 NTPase AAA_30 PF13604.6 KFM24434.1 - 0.049 13.4 0.3 0.091 12.5 0.3 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KFM24434.1 - 0.061 13.7 0.1 0.12 12.7 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KFM24434.1 - 0.11 12.3 0.2 0.33 10.7 0.2 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KFM24434.1 - 0.11 13.0 0.1 0.2 12.1 0.1 1.4 1 0 0 1 1 1 0 ABC transporter DAP3 PF10236.9 KFM24434.1 - 0.13 11.4 0.2 0.2 10.8 0.2 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_24 PF13479.6 KFM24434.1 - 0.16 11.7 0.0 0.85 9.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 KFM24434.1 - 0.17 12.0 0.3 0.37 10.9 0.3 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2075 PF09848.9 KFM24434.1 - 0.17 11.1 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Cpn10 PF00166.21 KFM24435.1 - 2.8e-44 149.1 0.1 1.1e-26 92.7 0.0 2.2 2 0 0 2 2 2 2 Chaperonin 10 Kd subunit LRR_4 PF12799.7 KFM24435.1 - 0.033 14.6 4.3 78 3.9 0.0 5.8 6 1 1 7 7 7 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFM24435.1 - 5.4 6.9 8.1 21 5.0 0.1 3.9 5 0 0 5 5 5 0 Leucine rich repeat PHD PF00628.29 KFM24436.1 - 2.4e-06 27.3 8.7 2.4e-06 27.3 8.7 2.9 3 0 0 3 3 3 1 PHD-finger zf-CW PF07496.15 KFM24436.1 - 2.6e-06 27.4 0.9 2.6e-06 27.4 0.9 4.2 5 1 0 5 5 5 1 CW-type Zinc Finger PWWP PF00855.17 KFM24436.1 - 0.0006 20.2 0.0 0.0013 19.1 0.0 1.6 1 0 0 1 1 1 1 PWWP domain zf-C3HC4_3 PF13920.6 KFM24436.1 - 4.3 7.3 12.1 4.3 7.3 7.2 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H PF13771.6 KFM24436.1 - 8.2 6.8 12.7 0.077 13.3 4.3 2.1 3 0 0 3 3 3 0 PHD-like zinc-binding domain tRNA_synthFbeta PF17759.1 KFM24437.1 - 6e-45 153.3 0.0 8.6e-45 152.8 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 KFM24437.1 - 1.8e-34 117.8 0.1 4.6e-34 116.5 0.1 1.7 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 KFM24437.1 - 4.3e-16 59.1 0.0 7e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 KFM24437.1 - 1.7e-15 57.1 0.0 6.3e-13 48.8 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetase B5 domain PAP2 PF01569.21 KFM24438.1 - 3.5e-18 65.7 0.1 3.5e-18 65.7 0.1 2.4 2 1 0 2 2 2 1 PAP2 superfamily PNTB_4TM PF12769.7 KFM24438.1 - 0.056 13.9 0.3 0.056 13.9 0.3 2.0 2 0 0 2 2 2 0 4TM region of pyridine nucleotide transhydrogenase, mitoch His_Phos_1 PF00300.22 KFM24440.1 - 1.5e-17 63.9 0.7 8.3e-17 61.5 0.1 2.2 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) SQHop_cyclase_C PF13243.6 KFM24441.1 - 1.9e-52 178.4 0.3 1.3e-47 162.5 0.9 2.8 2 1 1 3 3 3 3 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KFM24441.1 - 1.2e-44 152.6 0.1 1.3e-36 126.2 0.0 3.6 3 1 0 3 3 3 3 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 KFM24441.1 - 2.9e-39 132.5 8.3 7.2e-11 41.6 0.1 5.7 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.10 KFM24441.1 - 0.0091 15.4 0.0 8.1 5.7 0.0 3.6 3 1 1 4 4 4 1 Pectic acid lyase DUF4087 PF13316.6 KFM24441.1 - 0.037 14.5 0.1 0.14 12.7 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4087) Mago-bind PF09282.10 KFM24441.1 - 0.53 10.2 2.4 0.3 11.0 0.1 1.8 2 0 0 2 2 2 0 Mago binding Tab2_like PF06485.11 KFM24442.1 - 5.6e-71 239.2 0.0 6.3e-71 239.0 0.0 1.0 1 0 0 1 1 1 1 RNA-binding protein Tab2/Atab2 5_nucleotid PF05761.14 KFM24443.1 - 4.2e-140 467.7 0.0 6.6e-139 463.7 0.0 2.0 1 1 0 1 1 1 1 5' nucleotidase family TPR_1 PF00515.28 KFM24445.1 - 3e-14 52.1 0.1 0.00021 21.0 0.3 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat RPAP3_C PF13877.6 KFM24445.1 - 1.6e-12 47.8 0.0 3.1e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_2 PF07719.17 KFM24445.1 - 1.6e-11 43.3 3.4 0.001 19.0 0.0 3.8 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 KFM24445.1 - 8.3e-07 29.1 1.8 8.3e-07 29.1 1.8 3.7 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFM24445.1 - 9.4e-06 25.4 1.6 0.28 11.5 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFM24445.1 - 2.2e-05 25.0 10.0 0.00034 21.2 1.3 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFM24445.1 - 4.3e-05 23.1 0.0 0.00014 21.4 0.0 1.9 2 0 0 2 2 2 1 TPR repeat TPR_7 PF13176.6 KFM24445.1 - 6.2e-05 22.7 1.1 2.2 8.5 0.1 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFM24445.1 - 0.0018 19.0 9.9 0.98 10.4 1.8 4.7 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFM24445.1 - 0.0026 18.0 0.0 1.7 9.2 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFM24445.1 - 0.0035 17.6 8.8 0.0044 17.3 1.6 2.7 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFM24445.1 - 0.27 11.8 4.0 0.83 10.2 0.2 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFM24445.1 - 0.61 10.0 4.3 1.6 8.7 0.4 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat tRNA-synt_1b PF00579.25 KFM24446.1 - 2.3e-71 240.5 0.0 2.9e-71 240.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 KFM24446.1 - 2.5e-07 30.3 0.4 4.5e-07 29.5 0.4 1.5 1 0 0 1 1 1 1 S4 domain ATE_C PF04377.15 KFM24446.1 - 0.28 11.8 0.0 0.5 11.0 0.0 1.3 1 0 0 1 1 1 0 Arginine-tRNA-protein transferase, C terminus EccE PF11203.8 KFM24446.1 - 2.7 8.4 5.3 1.5 9.2 0.2 2.9 3 1 0 3 3 3 0 Putative type VII ESX secretion system translocon, EccE Peptidase_M1 PF01433.20 KFM24447.1 - 1.5e-46 158.7 0.0 3.1e-46 157.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 KFM24447.1 - 3.9e-36 123.6 0.1 7.1e-36 122.7 0.1 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 KFM24447.1 - 9.7e-21 74.8 0.0 3e-18 66.7 0.0 2.2 1 1 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_MA_2 PF13485.6 KFM24447.1 - 0.077 12.7 0.1 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 Peptidase MA superfamily Peptidase_M48 PF01435.18 KFM24447.1 - 0.098 12.4 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M48 dCMP_cyt_deam_1 PF00383.23 KFM24448.1 - 2.4e-25 88.3 0.0 3.4e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KFM24448.1 - 5.9e-11 42.3 0.0 8.5e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 KFM24448.1 - 0.068 13.2 1.3 0.2 11.7 0.1 2.2 2 1 1 3 3 3 0 Bd3614-like deaminase APOBEC3 PF18771.1 KFM24448.1 - 0.17 12.0 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 APOBEC3 RRM_1 PF00076.22 KFM24449.1 - 1.6e-07 31.0 0.0 3.4e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DHBP_synthase PF00926.19 KFM24449.1 - 0.12 11.8 0.1 0.2 11.1 0.1 1.3 1 0 0 1 1 1 0 3,4-dihydroxy-2-butanone 4-phosphate synthase PNTB PF02233.16 KFM24450.1 - 0.11 11.4 1.4 0.17 10.8 1.4 1.3 1 0 0 1 1 1 0 NAD(P) transhydrogenase beta subunit COX8 PF02285.15 KFM24450.1 - 0.12 12.2 0.9 0.63 10.0 0.2 2.4 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIII DUF4093 PF13331.6 KFM24451.1 - 0.18 12.2 0.0 0.43 11.0 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4093) HMMR_N PF15905.5 KFM24452.1 - 0.0011 18.5 1.3 0.0011 18.5 1.3 3.4 3 0 0 3 3 3 2 Hyaluronan mediated motility receptor N-terminal DUF641 PF04859.12 KFM24452.1 - 1.2 9.5 0.0 1.2 9.5 0.0 4.4 3 2 0 3 3 3 0 Plant protein of unknown function (DUF641) Ribosomal_L14 PF00238.19 KFM24455.1 - 1.7e-43 147.6 1.6 1.9e-43 147.4 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Ufd2P_core PF10408.9 KFM24456.1 - 1.6e-135 453.2 0.0 1.9e-135 452.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 KFM24456.1 - 9.3e-22 77.0 0.3 2.3e-21 75.7 0.3 1.7 1 0 0 1 1 1 1 U-box domain AAA PF00004.29 KFM24457.1 - 9.2e-09 35.8 0.0 0.00073 20.0 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFM24457.1 - 5.6e-07 29.9 0.0 2.2e-06 28.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFM24457.1 - 3.5e-06 27.5 1.1 1.5e-05 25.5 0.2 2.6 2 1 0 2 2 2 1 AAA ATPase domain Cdc6_C PF09079.11 KFM24457.1 - 1.2e-05 25.2 0.0 2.3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_11 PF13086.6 KFM24457.1 - 0.019 14.8 0.0 0.03 14.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KFM24457.1 - 0.084 13.3 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 RNA helicase SAM_decarbox PF01536.16 KFM24458.1 - 1.6e-88 297.1 0.0 2.1e-88 296.7 0.0 1.1 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase Orn_Arg_deC_N PF02784.16 KFM24458.1 - 4.6e-28 98.2 0.0 7.2e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KFM24458.1 - 1.3e-09 38.2 0.0 2.4e-09 37.3 0.0 1.6 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain NAD_binding_10 PF13460.6 KFM24459.1 - 1.5e-18 67.4 0.2 2e-18 67.0 0.2 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Chloroa_b-bind PF00504.21 KFM24459.1 - 8.1e-07 29.7 6.2 0.0052 17.3 0.1 3.5 2 2 2 4 4 4 2 Chlorophyll A-B binding protein Semialdhyde_dh PF01118.24 KFM24459.1 - 5.5e-06 26.8 0.1 8.4e-06 26.2 0.1 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 KFM24459.1 - 4.7e-05 23.0 0.0 6.1e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KFM24459.1 - 7.2e-05 22.4 2.2 0.00022 20.9 2.2 1.7 1 1 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 KFM24459.1 - 0.012 15.8 0.0 0.02 15.2 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 KFM24459.1 - 0.091 11.9 0.0 3.3 6.8 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein HAD_2 PF13419.6 KFM24460.1 - 1.5e-15 57.7 0.0 2.2e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase zf-DNL PF05180.12 KFM24460.1 - 2.3e-13 49.8 0.0 4.6e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 DNL zinc finger Hydrolase PF00702.26 KFM24460.1 - 9.9e-09 35.8 0.0 1.6e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFM24460.1 - 0.034 14.5 0.0 0.055 13.9 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFM24460.1 - 0.038 14.1 0.0 0.096 12.8 0.0 1.7 1 0 0 1 1 1 0 HAD-hyrolase-like Ribosomal_L37ae PF01780.19 KFM24460.1 - 0.038 14.1 1.0 0.076 13.1 1.0 1.4 1 0 0 1 1 1 0 Ribosomal L37ae protein family MEDS PF14417.6 KFM24460.1 - 0.17 11.7 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain Oxysterol_BP PF01237.18 KFM24462.1 - 4.3e-58 196.9 0.0 4e-56 190.5 0.0 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein Zip PF02535.22 KFM24462.1 - 0.22 10.7 0.0 0.33 10.1 0.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter HAD_2 PF13419.6 KFM24463.1 - 2e-14 54.1 0.0 2.3e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFM24463.1 - 5e-10 39.3 0.0 1.4e-09 37.9 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 KFM24463.1 - 2e-09 38.1 0.0 3.4e-09 37.3 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PALP PF00291.25 KFM24464.1 - 2.1e-71 240.7 0.8 2.5e-71 240.5 0.8 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Sec1 PF00995.23 KFM24466.1 - 5.8e-96 323.0 0.0 2e-47 162.7 0.0 2.0 1 1 1 2 2 2 2 Sec1 family Mito_carr PF00153.27 KFM24466.1 - 7.9e-51 170.0 0.8 1.3e-21 76.3 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-NOSIP PF15906.5 KFM24467.1 - 4.8e-15 55.5 0.0 8.8e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Rtf2 PF04641.12 KFM24467.1 - 0.00086 18.8 0.1 1.4 8.2 0.0 2.7 2 1 1 3 3 3 3 Rtf2 RING-finger U-box PF04564.15 KFM24467.1 - 0.023 14.8 0.0 0.1 12.8 0.0 2.0 2 0 0 2 2 2 0 U-box domain RINGv PF12906.7 KFM24468.1 - 0.034 14.3 0.6 0.06 13.5 0.6 1.4 1 0 0 1 1 1 0 RING-variant domain DPBB_1 PF03330.18 KFM24470.1 - 9.7e-09 35.4 0.4 1.6e-06 28.3 0.4 2.3 2 0 0 2 2 2 2 Lytic transglycolase PP2C PF00481.21 KFM24471.1 - 3.2e-34 118.7 0.0 5.2e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KFM24471.1 - 0.0068 16.1 3.4 0.0068 16.1 3.4 2.3 2 1 0 2 2 2 1 Protein phosphatase 2C HMG_box PF00505.19 KFM24472.1 - 0.035 14.5 0.1 0.066 13.6 0.1 1.3 1 0 0 1 1 1 0 HMG (high mobility group) box Ehrlichia_rpt PF09528.10 KFM24472.1 - 0.15 11.5 0.1 0.53 9.8 0.0 1.9 2 0 0 2 2 2 0 Ehrlichia tandem repeat (Ehrlichia_rpt) Cys_Met_Meta_PP PF01053.20 KFM24473.1 - 1.1e-120 402.7 0.0 1.3e-120 402.5 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KFM24473.1 - 0.0061 15.9 0.4 5 6.3 0.0 2.8 3 0 0 3 3 3 2 DegT/DnrJ/EryC1/StrS aminotransferase family Ribosomal_L37 PF08561.10 KFM24475.1 - 3e-11 43.9 2.3 2.3e-08 34.6 0.3 2.1 1 1 1 2 2 2 2 Mitochondrial ribosomal protein L37 Med12 PF09497.10 KFM24475.1 - 0.0072 16.6 0.1 0.018 15.4 0.1 1.6 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Myb_DNA-binding PF00249.31 KFM24476.1 - 0.012 15.8 0.0 0.02 15.1 0.0 1.3 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFM24476.1 - 0.051 13.8 0.0 0.077 13.3 0.0 1.3 1 0 0 1 1 1 0 Myb-like DNA-binding domain MOZ_SAS PF01853.18 KFM24477.1 - 9.3e-82 273.0 0.0 1.3e-81 272.5 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KFM24477.1 - 1e-17 63.4 2.9 2.4e-17 62.3 2.9 1.7 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 KFM24477.1 - 1.3e-07 31.3 0.9 3.3e-07 30.1 0.9 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 KFM24477.1 - 0.01 16.3 0.0 0.023 15.1 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Chloroa_b-bind PF00504.21 KFM24480.1 - 1.3e-48 165.6 0.3 1.8e-48 165.1 0.0 1.3 2 0 0 2 2 2 1 Chlorophyll A-B binding protein DEAD_2 PF06733.15 KFM24481.1 - 1.7e-47 161.3 0.0 3.2e-47 160.4 0.0 1.5 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.6 KFM24481.1 - 5.7e-41 140.5 0.0 1e-40 139.7 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain HBB PF06777.11 KFM24481.1 - 2.1e-35 122.1 0.0 3.3e-31 108.5 0.0 2.4 2 0 0 2 2 2 2 Helical and beta-bridge domain ResIII PF04851.15 KFM24481.1 - 3.8e-07 30.3 0.1 2.6e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFM24481.1 - 0.00052 19.8 0.2 0.035 13.9 0.0 2.9 3 0 0 3 3 3 1 DEAD/DEAH box helicase SNF2_N PF00176.23 KFM24481.1 - 0.0021 16.9 0.1 0.68 8.6 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain AAA_11 PF13086.6 KFM24481.1 - 0.17 11.7 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain MutS_V PF00488.21 KFM24482.1 - 8.5e-10 39.0 2.2 4.7e-05 23.5 0.1 2.3 1 1 1 2 2 2 2 MutS domain V APG6_N PF17675.1 KFM24482.1 - 0.57 10.7 8.7 0.092 13.3 4.4 1.9 2 0 0 2 2 2 0 Apg6 coiled-coil region Hexokinase_1 PF00349.21 KFM24483.1 - 3.9e-52 177.0 0.0 5e-52 176.7 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 KFM24483.1 - 2.8e-39 135.0 0.0 5.5e-28 98.0 0.0 2.2 1 1 1 2 2 2 2 Hexokinase Med12 PF09497.10 KFM24486.1 - 6.8e-11 42.3 0.0 3e-10 40.2 0.0 2.1 2 0 0 2 2 2 1 Transcription mediator complex subunit Med12 AAA_25 PF13481.6 KFM24486.1 - 0.068 12.7 2.0 0.39 10.3 0.9 2.5 1 1 1 2 2 2 0 AAA domain DUF601 PF04642.12 KFM24487.1 - 0.3 10.5 5.1 0.98 8.9 5.1 1.8 1 0 0 1 1 1 0 Protein of unknown function, DUF601 Jnk-SapK_ap_N PF09744.9 KFM24487.1 - 5.1 7.3 6.8 8.6 6.6 6.8 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Oxysterol_BP PF01237.18 KFM24489.1 - 1.5e-38 132.7 0.0 1.2e-31 109.9 0.0 2.0 2 0 0 2 2 2 2 Oxysterol-binding protein Pyr_redox_2 PF07992.14 KFM24490.1 - 3.6e-36 124.9 0.8 4.6e-29 101.6 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFM24490.1 - 1.7e-09 38.1 0.3 3.5e-07 30.7 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFM24490.1 - 0.0047 16.9 0.6 8.1 6.4 0.0 3.2 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KFM24490.1 - 0.018 15.3 1.6 5.4 7.3 0.0 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 KFM24490.1 - 0.33 10.2 2.5 13 5.0 1.1 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain MAD PF05557.13 KFM24491.1 - 0.0042 15.5 7.9 0.081 11.3 5.3 2.0 1 1 1 2 2 2 2 Mitotic checkpoint protein E2R135 PF11570.8 KFM24491.1 - 0.068 13.5 0.1 0.068 13.5 0.1 2.1 2 1 0 2 2 2 0 Coiled-coil receptor-binding R-domain of colicin E2 Fez1 PF06818.15 KFM24491.1 - 0.35 11.3 10.8 0.11 12.9 5.8 2.0 1 1 1 2 2 2 0 Fez1 DUF4201 PF13870.6 KFM24491.1 - 1.4 8.6 5.4 0.89 9.3 0.4 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) SlyX PF04102.12 KFM24491.1 - 3.4 8.4 7.1 3.9 8.2 0.1 3.6 4 0 0 4 4 4 0 SlyX Atg14 PF10186.9 KFM24491.1 - 4 6.4 10.0 10 5.1 10.1 1.7 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Helicase_C PF00271.31 KFM24492.1 - 3.1e-18 66.1 0.0 2.8e-15 56.6 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 KFM24492.1 - 3.5e-17 62.7 0.0 1.8e-16 60.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 KFM24492.1 - 7.5e-06 26.6 0.0 1.6e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 RecQ zinc-binding Med26 PF08711.11 KFM24492.1 - 0.00094 19.2 0.0 0.0024 17.8 0.0 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain ABC_tran_CTD PF16326.5 KFM24493.1 - 0.061 13.6 1.1 0.15 12.3 1.1 1.6 1 0 0 1 1 1 0 ABC transporter C-terminal domain ABC_tran PF00005.27 KFM24494.1 - 1.1e-16 61.6 0.0 1.7e-16 61.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 KFM24494.1 - 1.8e-12 47.1 17.1 3.5e-12 46.2 17.1 1.4 1 0 0 1 1 1 1 ABC-2 type transporter RsgA_GTPase PF03193.16 KFM24494.1 - 0.005 16.7 0.3 0.02 14.8 0.2 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 KFM24494.1 - 0.0091 15.8 0.0 2.7 7.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system EF-hand_7 PF13499.6 KFM24494.1 - 0.019 15.4 0.0 0.039 14.4 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair ABC2_membrane_3 PF12698.7 KFM24494.1 - 0.022 13.9 15.3 0.037 13.1 15.3 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein AAA_30 PF13604.6 KFM24494.1 - 0.13 12.0 0.4 0.27 10.9 0.4 1.5 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KFM24494.1 - 0.15 11.8 0.4 0.36 10.6 0.4 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 KFM24494.1 - 0.18 11.4 0.1 0.33 10.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain Misat_Tub_SegII PF10644.9 KFM24495.1 - 1.9e-07 31.4 0.3 3.4e-07 30.6 0.3 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KFM24495.1 - 0.001 18.8 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin domain DAGK_cat PF00781.24 KFM24496.1 - 2.6e-19 69.1 0.0 3.7e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain BHD_3 PF10405.9 KFM24497.1 - 5.4e-15 55.5 0.0 9.4e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.15 KFM24497.1 - 2e-09 37.3 0.0 4.4e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_1 PF10403.9 KFM24497.1 - 1.3e-07 31.3 0.1 2.2e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 Transglut_core PF01841.19 KFM24497.1 - 0.00025 21.5 5.7 0.0011 19.4 1.0 3.3 3 0 0 3 3 3 1 Transglutaminase-like superfamily GNT-I PF03071.15 KFM24498.1 - 2.3e-55 188.1 0.0 3.1e-55 187.7 0.0 1.1 1 0 0 1 1 1 1 GNT-I family Glyco_transf_18 PF15024.6 KFM24498.1 - 0.0016 17.1 2.9 0.0021 16.7 2.9 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 18 Glyco_tranf_2_3 PF13641.6 KFM24498.1 - 0.032 14.1 0.0 0.066 13.1 0.0 1.5 1 1 0 1 1 1 0 Glycosyltransferase like family 2 MGAT2 PF05060.14 KFM24498.1 - 0.035 13.2 0.0 0.45 9.5 0.0 2.1 2 0 0 2 2 2 0 N-acetylglucosaminyltransferase II (MGAT2) Glycos_transf_2 PF00535.26 KFM24498.1 - 0.039 13.7 0.0 0.1 12.4 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase family 2 Fasciclin PF02469.22 KFM24499.1 - 4.6e-11 43.0 0.0 6.4e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain Pkinase PF00069.25 KFM24500.1 - 8e-20 71.3 0.0 1.2e-17 64.2 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFM24500.1 - 9.5e-11 41.5 0.0 2.4e-09 36.9 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KFM24501.1 - 3e-82 275.9 0.0 4.3e-61 206.6 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFM24501.1 - 1e-36 126.6 0.3 2.1e-23 82.9 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase_C PF00433.24 KFM24501.1 - 4.4e-09 36.9 0.2 0.007 17.0 0.0 2.9 2 0 0 2 2 2 2 Protein kinase C terminal domain Pheromone PF08015.11 KFM24501.1 - 0.011 16.7 1.3 17 6.5 0.0 3.7 4 0 0 4 4 4 0 Fungal mating-type pheromone Kdo PF06293.14 KFM24501.1 - 0.013 14.8 0.1 0.032 13.6 0.1 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFM24501.1 - 0.014 15.4 8.9 0.073 13.0 0.1 3.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KFM24501.1 - 0.017 14.5 1.3 0.042 13.2 0.0 2.2 3 0 0 3 3 3 0 Kinase-like Seadorna_VP7 PF07387.11 KFM24501.1 - 0.068 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PFO_beta_C PF12367.8 KFM24501.1 - 0.099 12.8 0.1 0.23 11.6 0.1 1.5 1 0 0 1 1 1 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal adh_short_C2 PF13561.6 KFM24502.1 - 7.6e-62 208.9 0.9 9.3e-62 208.6 0.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFM24502.1 - 1.1e-48 165.3 0.1 1.4e-48 164.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFM24502.1 - 3.3e-08 33.7 0.1 4.9e-08 33.1 0.1 1.3 1 0 0 1 1 1 1 KR domain ELFV_dehydrog PF00208.21 KFM24503.1 - 2.4e-75 253.4 0.5 3.2e-75 253.0 0.5 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 KFM24503.1 - 2.7e-50 169.6 0.0 4.6e-50 168.8 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.6 KFM24503.1 - 0.0011 19.4 0.0 0.002 18.5 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding C2 PF00168.30 KFM24505.1 - 1.4e-09 38.1 0.0 1.8e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 C2 domain EstA_Ig_like PF18435.1 KFM24505.1 - 0.038 14.2 0.0 0.057 13.6 0.0 1.2 1 0 0 1 1 1 0 Esterase Ig-like N-terminal domain CBFD_NFYB_HMF PF00808.23 KFM24506.1 - 1.8e-19 69.8 2.5 3.2e-19 69.0 1.7 1.9 2 1 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFM24506.1 - 4.5e-14 52.9 1.1 9e-14 52.0 1.1 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 KFM24506.1 - 0.13 12.5 0.4 0.23 11.7 0.0 1.6 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) ALG11_N PF15924.5 KFM24507.1 - 2.1e-51 175.0 0.0 2.9e-51 174.5 0.0 1.1 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 KFM24507.1 - 5.5e-19 68.3 0.0 8.8e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KFM24507.1 - 1.9e-10 41.3 0.1 5.4e-10 39.8 0.1 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KFM24507.1 - 0.034 14.5 0.3 0.073 13.5 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferases group 1 Rho_N PF07498.12 KFM24507.1 - 0.16 12.0 0.2 0.36 10.8 0.2 1.6 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain DnaJ PF00226.31 KFM24508.1 - 1.6e-16 60.2 0.0 2.7e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain zf-B_box PF00643.24 KFM24508.1 - 2.5e-05 24.3 4.3 4.9e-05 23.4 4.3 1.3 1 0 0 1 1 1 1 B-box zinc finger CS PF04969.16 KFM24508.1 - 0.017 16.1 0.0 8.7 7.4 0.0 2.5 2 0 0 2 2 2 0 CS domain Siva PF05458.12 KFM24508.1 - 0.18 11.5 2.8 0.34 10.6 2.8 1.4 1 0 0 1 1 1 0 Cd27 binding protein (Siva) zf-HIT PF04438.16 KFM24508.1 - 1.8 8.5 6.3 3.8 7.5 6.3 1.5 1 0 0 1 1 1 0 HIT zinc finger Glyco_transf_49 PF13896.6 KFM24511.1 - 2.2e-28 99.6 0.0 7.2e-24 84.7 0.0 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glycos_transf_2 PF00535.26 KFM24511.1 - 0.1 12.4 0.1 0.34 10.7 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 2 Gas_vesicle_C PF01304.17 KFM24511.1 - 6.5 6.8 5.1 1.4 8.9 1.6 1.7 2 0 0 2 2 2 0 Gas vesicles protein GVPc repeated domain LRR_4 PF12799.7 KFM24512.1 - 6.9e-07 29.5 2.9 0.00093 19.6 0.5 2.3 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFM24512.1 - 2.2e-05 24.2 0.4 3.4e-05 23.5 0.4 1.3 1 0 0 1 1 1 1 Leucine rich repeat LRR_9 PF14580.6 KFM24512.1 - 0.0019 17.7 0.0 0.0035 16.8 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat HsbA PF12296.8 KFM24512.1 - 0.036 14.5 0.1 0.13 12.7 0.1 1.9 1 0 0 1 1 1 0 Hydrophobic surface binding protein A FA_desaturase PF00487.24 KFM24513.1 - 1.2e-18 67.9 29.7 1.2e-18 67.9 29.7 1.7 1 1 1 2 2 2 1 Fatty acid desaturase EF-hand_6 PF13405.6 KFM24513.1 - 3.3e-14 51.5 0.0 0.0053 16.6 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 KFM24513.1 - 4.7e-14 52.6 0.0 1e-06 29.1 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KFM24513.1 - 4.8e-14 50.8 0.0 0.00059 19.2 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KFM24513.1 - 1e-08 34.9 0.0 0.0034 17.2 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KFM24513.1 - 6.3e-05 22.3 0.4 0.61 9.7 0.0 3.4 3 0 0 3 3 3 2 EF hand Semialdhyde_dhC PF02774.18 KFM24514.1 - 1.3e-45 155.7 0.0 2e-45 155.1 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 KFM24514.1 - 1.9e-30 105.8 0.1 5.2e-30 104.4 0.1 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 KFM24514.1 - 0.0072 15.9 0.1 0.018 14.6 0.1 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain START PF01852.19 KFM24515.1 - 1e-05 25.1 0.1 1.6e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 START domain DAGK_cat PF00781.24 KFM24516.1 - 1.1e-53 180.2 2.9 4.3e-29 100.7 0.3 2.3 2 0 0 2 2 2 2 Diacylglycerol kinase catalytic domain PFK PF00365.20 KFM24516.1 - 4.5e-06 26.2 0.0 0.082 12.2 0.0 2.2 2 0 0 2 2 2 2 Phosphofructokinase NAD_kinase PF01513.21 KFM24516.1 - 7.8e-06 25.3 0.7 0.1 11.8 0.1 2.3 2 0 0 2 2 2 2 ATP-NAD kinase DUF1480 PF07351.13 KFM24516.1 - 0.073 13.4 0.0 19 5.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1480) Ret2_MD PF18528.1 KFM24516.1 - 0.17 12.3 0.0 3.4 8.1 0.0 2.4 2 0 0 2 2 2 0 RNA editing 3' terminal uridylyl transferase 2 middle domain RCC1 PF00415.18 KFM24517.1 - 2.3e-37 127.4 25.8 5.8e-10 39.6 0.5 6.8 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFM24517.1 - 2.7e-25 87.6 24.4 1.4e-08 34.3 1.5 5.4 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat Elongin_A PF06881.11 KFM24517.1 - 0.0029 18.1 0.0 0.0045 17.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A DNA_pol_B_thumb PF14791.6 KFM24518.1 - 9.3e-17 61.0 0.0 1.6e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.6 KFM24519.1 - 1.7e-06 28.3 0.1 1.7e-05 25.1 0.1 2.0 1 1 0 1 1 1 1 Helix-hairpin-helix domain DUF4025 PF13217.6 KFM24519.1 - 0.091 12.6 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4025) HPP PF04982.13 KFM24520.1 - 3.4e-36 124.1 10.4 3.4e-36 124.1 10.4 3.0 3 1 0 3 3 3 1 HPP family TcdB_toxin_midN PF12256.8 KFM24520.1 - 0.14 11.5 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/N-terminal region DUF1230 PF06799.11 KFM24521.1 - 1.3e-50 171.2 0.1 1.6e-50 171.0 0.1 1.1 1 0 0 1 1 1 1 Conserved in the green lineage and diatoms 27 DUF3325 PF11804.8 KFM24521.1 - 2.6 8.2 10.1 1 9.6 2.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) NACHT_sigma PF17106.5 KFM24522.1 - 0.03 14.4 0.0 14 5.9 0.0 2.6 2 0 0 2 2 2 0 Sigma domain on NACHT-NTPases DUF364 PF04016.12 KFM24522.1 - 0.069 12.7 0.1 15 5.1 0.0 2.3 2 0 0 2 2 2 0 Putative heavy-metal chelation DUF4851 PF16143.5 KFM24522.1 - 0.14 11.6 5.4 0.33 10.4 0.3 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4851) Citrate_synt PF00285.21 KFM24523.1 - 2.1e-24 86.3 0.0 1.4e-21 77.0 0.0 2.2 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 KFM24523.1 - 2.5e-10 40.4 0.3 4.2e-10 39.7 0.3 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KFM24523.1 - 3.7e-05 23.5 0.4 0.00025 20.9 0.2 2.2 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding PF02629.19 KFM24523.1 - 0.027 15.1 0.0 0.062 14.0 0.0 1.6 1 0 0 1 1 1 0 CoA binding domain DSPc PF00782.20 KFM24525.1 - 4.9e-28 97.6 0.0 6.6e-28 97.2 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KFM24525.1 - 0.0029 17.9 0.0 0.0068 16.7 0.0 1.7 2 0 0 2 2 2 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 KFM24525.1 - 0.08 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF442 PF04273.13 KFM24525.1 - 0.11 12.6 0.0 0.64 10.1 0.0 2.1 2 0 0 2 2 2 0 Putative phosphatase (DUF442) DUF2334 PF10096.9 KFM24525.1 - 0.22 11.2 0.0 0.31 10.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) FKBP_C PF00254.28 KFM24526.1 - 7.3e-16 58.3 0.0 1.1e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase MaoC_dehydratas PF01575.19 KFM24527.1 - 2.4e-09 36.8 0.0 3.3e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KFM24527.1 - 0.00019 21.6 0.0 0.00055 20.1 0.0 1.8 2 1 0 2 2 2 1 N-terminal half of MaoC dehydratase 4HBT PF03061.22 KFM24527.1 - 0.021 15.2 0.0 0.044 14.1 0.0 1.5 1 0 0 1 1 1 0 Thioesterase superfamily RAP PF08373.10 KFM24528.1 - 2e-11 43.8 0.0 4.6e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 RAP domain MTES_1575 PF18741.1 KFM24528.1 - 0.0021 18.2 0.0 0.0049 17.0 0.0 1.6 1 0 0 1 1 1 1 REase_MTES_1575 Spt5_N PF11942.8 KFM24528.1 - 0.0084 17.1 4.4 0.025 15.5 2.6 2.3 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal SDA1 PF05285.12 KFM24528.1 - 0.053 13.0 2.8 0.079 12.4 2.8 1.1 1 0 0 1 1 1 0 SDA1 Myc_N PF01056.18 KFM24528.1 - 0.26 11.1 2.4 0.44 10.4 2.4 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Radial_spoke PF04712.12 KFM24528.1 - 0.34 9.8 2.4 0.51 9.2 2.4 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Abhydrolase_6 PF12697.7 KFM24530.1 - 0.00081 20.1 2.8 0.00099 19.8 2.8 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 KFM24530.1 - 0.016 14.8 0.0 0.022 14.4 0.0 1.3 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 KFM24530.1 - 0.09 12.0 0.0 0.47 9.7 0.0 1.9 1 1 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFM24530.1 - 0.09 12.4 0.1 0.2 11.3 0.1 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold WD40 PF00400.32 KFM24531.1 - 1.1e-12 48.2 6.3 0.0063 17.3 0.0 5.1 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM24531.1 - 9.3e-06 25.9 0.0 0.011 16.0 0.0 4.0 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFM24531.1 - 0.18 10.7 0.0 2.4 7.0 0.0 2.1 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Kinesin PF00225.23 KFM24532.1 - 1.1e-102 343.5 0.0 1.6e-102 342.9 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFM24532.1 - 6.2e-24 84.6 0.0 9.8e-24 84.0 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding DUF641 PF04859.12 KFM24532.1 - 0.03 14.7 6.1 1.9 8.8 0.8 2.8 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Sox_N PF12444.8 KFM24532.1 - 0.32 12.2 4.0 0.32 12.2 0.1 3.0 3 0 0 3 3 3 0 Sox developmental protein N terminal Tup_N PF08581.10 KFM24532.1 - 0.84 10.0 4.8 1.9 8.9 0.9 3.1 3 0 0 3 3 3 0 Tup N-terminal YkpC PF17447.2 KFM24533.1 - 2.6 9.0 5.8 6.1 7.9 2.2 2.6 2 0 0 2 2 2 0 Uncharacterized YkpC-like AMP-binding PF00501.28 KFM24534.1 - 3.8e-38 131.2 0.0 4.7e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFM24534.1 - 3.1e-11 44.1 1.1 4.7e-11 43.5 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Tctex-1 PF03645.13 KFM24535.1 - 6.8e-16 58.4 0.1 9.9e-16 57.9 0.1 1.2 1 0 0 1 1 1 1 Tctex-1 family HARE-HTH PF05066.13 KFM24535.1 - 3.6e-14 52.9 0.0 9.4e-14 51.6 0.0 1.7 2 0 0 2 2 2 1 HB1, ASXL, restriction endonuclease HTH domain TPR_12 PF13424.6 KFM24535.1 - 0.05 13.9 1.5 0.19 12.0 1.5 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat DNA_methylase PF00145.17 KFM24536.1 - 1.3e-31 110.2 0.0 3.4e-23 82.5 0.0 2.1 2 0 0 2 2 2 2 C-5 cytosine-specific DNA methylase Cyto_heme_lyase PF01265.17 KFM24538.1 - 1.2e-58 199.0 4.3 1.2e-57 195.8 4.3 1.9 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase CAF1C_H4-bd PF12265.8 KFM24539.1 - 7.2e-28 96.7 1.0 2e-27 95.2 0.3 2.2 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KFM24539.1 - 5.6e-26 90.3 6.2 8.6e-07 29.6 0.0 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.11 KFM24539.1 - 4.2e-05 23.5 0.1 0.003 17.5 0.0 3.2 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 KFM24539.1 - 0.00056 20.2 0.5 0.016 15.5 0.0 3.2 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Chloroa_b-bind PF00504.21 KFM24540.1 - 1.9e-17 64.3 0.0 2.9e-17 63.7 0.0 1.4 1 1 0 1 1 1 1 Chlorophyll A-B binding protein Chloroa_b-bind PF00504.21 KFM24541.1 - 4.9e-45 153.9 0.0 7.6e-45 153.3 0.0 1.3 1 0 0 1 1 1 1 Chlorophyll A-B binding protein WD40 PF00400.32 KFM24542.1 - 5.9e-17 61.7 6.4 0.00061 20.6 0.0 6.1 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM24542.1 - 2e-06 28.0 0.0 2.6 8.4 0.0 4.3 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFM24542.1 - 0.00081 18.8 0.0 0.0016 17.8 0.0 1.3 1 1 0 1 1 1 1 WD40-like domain Nup160 PF11715.8 KFM24542.1 - 0.0023 16.7 0.3 0.13 10.9 0.1 2.8 1 1 1 2 2 2 2 Nucleoporin Nup120/160 AI-2E_transport PF01594.16 KFM24544.1 - 0.026 13.7 22.5 0.13 11.4 17.3 3.0 2 1 0 2 2 2 0 AI-2E family transporter TMEM135_C_rich PF15982.5 KFM24545.1 - 3.3e-10 40.7 0.1 2.9e-08 34.4 0.0 2.9 3 0 0 3 3 3 1 N-terminal cysteine-rich region of Transmembrane protein 135 Tim17 PF02466.19 KFM24545.1 - 0.028 14.8 3.1 0.15 12.5 2.7 2.3 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Mpv17_PMP22 PF04117.12 KFM24546.1 - 1.2e-21 76.7 0.6 1.2e-21 76.7 0.6 1.6 2 0 0 2 2 2 1 Mpv17 / PMP22 family DNA_pol3_delta2 PF13177.6 KFM24547.1 - 3.5e-12 46.4 0.1 1.2e-11 44.7 0.1 1.8 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 KFM24547.1 - 3.2e-06 27.6 0.0 8e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 KFM24547.1 - 0.00012 22.4 0.1 0.00031 21.1 0.1 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain RuvB_N PF05496.12 KFM24547.1 - 0.00023 20.9 0.0 0.021 14.6 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KFM24547.1 - 0.00054 20.4 1.5 0.088 13.2 1.5 2.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFM24547.1 - 0.0011 19.2 0.0 0.0061 16.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 KFM24547.1 - 0.0069 16.5 0.0 0.032 14.4 0.0 2.1 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF815 PF05673.13 KFM24547.1 - 0.0081 15.3 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 KFM24547.1 - 0.073 12.4 0.0 3.5 7.0 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 KFM24547.1 - 0.073 12.8 0.1 0.45 10.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain CHB_HEX PF03173.13 KFM24547.1 - 0.074 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative carbohydrate binding domain AAA_5 PF07728.14 KFM24547.1 - 0.11 12.4 0.3 0.63 10.0 0.3 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 KFM24547.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.9 1 1 0 1 1 1 0 Rad17 P-loop domain ABC_tran PF00005.27 KFM24547.1 - 0.14 12.7 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 KFM24547.1 - 0.18 11.7 0.0 4.9 7.0 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Cyclin_C PF02984.19 KFM24548.1 - 8.2e-13 48.5 0.3 1.6e-12 47.6 0.3 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain Cyclin_N PF00134.23 KFM24548.1 - 1.5e-07 31.2 3.1 1.1e-06 28.4 0.9 2.5 2 1 0 2 2 2 1 Cyclin, N-terminal domain DUF3871 PF12987.7 KFM24548.1 - 0.19 10.5 0.0 0.25 10.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3871) Efg1 PF10153.9 KFM24549.1 - 2.1e-28 99.0 7.1 3.5e-28 98.2 7.1 1.4 1 0 0 1 1 1 1 rRNA-processing protein Efg1 Oxidored_nitro PF00148.19 KFM24549.1 - 0.022 13.5 0.5 0.094 11.4 0.5 1.8 1 1 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase ABC_tran_CTD PF16326.5 KFM24549.1 - 0.93 9.8 11.0 0.13 12.6 1.2 3.2 3 0 0 3 3 3 0 ABC transporter C-terminal domain DUF3769 PF12600.8 KFM24550.1 - 9e-07 28.1 0.0 0.01 14.8 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF3769) Esterase PF00756.20 KFM24551.1 - 1.1e-53 182.5 0.1 1.1e-52 179.3 0.1 1.9 1 1 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 KFM24551.1 - 7.4e-05 22.5 0.0 7.8e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFM24551.1 - 9.1e-05 21.8 0.4 0.00027 20.3 0.3 1.8 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KFM24551.1 - 0.0021 17.6 0.1 0.0031 17.0 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 KFM24551.1 - 0.0021 17.6 0.3 0.006 16.1 0.0 1.7 2 0 0 2 2 2 1 Esterase PHB depolymerase Abhydrolase_6 PF12697.7 KFM24551.1 - 0.0068 17.0 0.3 0.015 15.9 0.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 KFM24551.1 - 0.14 11.0 0.0 0.3 10.0 0.0 1.5 2 0 0 2 2 2 0 Chlorophyllase enzyme MCM PF00493.23 KFM24552.1 - 3.4e-97 324.0 0.0 5.1e-97 323.4 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KFM24552.1 - 3.2e-25 88.4 0.0 5.8e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_N PF14551.6 KFM24552.1 - 1.4e-16 60.9 0.0 2.8e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 MCM N-terminal domain MCM_lid PF17855.1 KFM24552.1 - 4.4e-12 46.3 0.3 4.4e-12 46.3 0.3 2.4 3 0 0 3 3 3 1 MCM AAA-lid domain AAA_5 PF07728.14 KFM24552.1 - 9.8e-06 25.6 0.0 2.7e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KFM24552.1 - 1.1e-05 24.9 0.0 7.4e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KFM24552.1 - 0.036 13.9 0.0 0.097 12.5 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PIG-S PF10510.9 KFM24552.1 - 0.048 12.5 0.2 0.1 11.4 0.1 1.6 2 0 0 2 2 2 0 Phosphatidylinositol-glycan biosynthesis class S protein Putative_PNPOx PF01243.20 KFM24554.1 - 4.4e-07 30.0 0.1 7.8e-07 29.2 0.1 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_oxidase_2 PF13883.6 KFM24554.1 - 4.6e-07 29.9 0.0 1.5e-06 28.3 0.0 1.9 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF2470 PF10615.9 KFM24554.1 - 2.7e-06 27.9 0.0 5.3e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) TruB_N PF01509.18 KFM24555.1 - 1.2e-43 149.1 0.0 1.4e-43 148.8 0.0 1.1 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KFM24555.1 - 2.9e-07 30.5 0.1 7.8e-07 29.2 0.1 1.7 2 0 0 2 2 2 1 tRNA pseudouridylate synthase B C-terminal domain Semialdhyde_dh PF01118.24 KFM24555.1 - 0.013 15.9 0.0 0.022 15.2 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain PKS_DE PF18369.1 KFM24556.1 - 2.4 8.8 5.4 1.6 9.3 0.3 2.3 2 0 0 2 2 2 0 Polyketide synthase dimerisation element domain RsfS PF02410.15 KFM24557.1 - 1.1e-16 61.1 0.5 4.3e-15 56.0 0.5 2.3 1 1 0 1 1 1 1 Ribosomal silencing factor during starvation SAP PF02037.27 KFM24557.1 - 0.0031 17.2 0.0 0.016 15.0 0.0 2.0 2 0 0 2 2 2 1 SAP domain eIF_4EBP PF05456.11 KFM24557.1 - 0.13 12.2 0.2 0.2 11.6 0.2 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Adaptin_N PF01602.20 KFM24559.1 - 3.9e-94 316.1 0.6 5.2e-47 160.6 0.0 2.0 1 1 1 2 2 2 2 Adaptin N terminal region Coatomer_g_Cpla PF16381.5 KFM24559.1 - 2.2e-23 82.5 0.0 5.4e-23 81.3 0.0 1.6 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform COP-gamma_platf PF08752.10 KFM24559.1 - 1.2e-14 54.7 7.9 7.1e-10 39.2 0.9 2.6 1 1 1 2 2 2 2 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.6 KFM24559.1 - 1.5e-05 25.3 16.4 0.5 10.8 0.4 6.2 5 2 2 7 7 7 3 HEAT repeats Cnd1 PF12717.7 KFM24559.1 - 2e-05 24.7 5.0 0.0096 16.0 0.2 2.9 2 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 DeoC PF01791.9 KFM24559.1 - 0.014 15.1 0.2 0.051 13.2 0.1 1.9 2 0 0 2 2 2 0 DeoC/LacD family aldolase Arm PF00514.23 KFM24559.1 - 0.16 12.1 1.5 3.7 7.7 0.2 3.8 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KFM24559.1 - 2.6 8.5 11.7 82 3.9 0.1 6.0 7 1 0 7 7 7 0 HEAT repeat Formyl_trans_N PF00551.19 KFM24560.1 - 1.7e-34 119.2 0.0 2.3e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 KFM24560.1 - 2e-13 50.4 0.0 3e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Nodulin-like PF06813.13 KFM24561.1 - 3e-45 154.7 10.9 1.2e-44 152.7 6.6 2.2 1 1 1 2 2 2 2 Nodulin-like MFS_1 PF07690.16 KFM24561.1 - 4.8e-15 55.3 54.3 3.1e-14 52.7 30.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Chloroa_b-bind PF00504.21 KFM24562.1 - 0.0004 20.9 0.0 0.00041 20.9 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Vps53_N PF04100.12 KFM24563.1 - 2e-63 214.7 0.0 1.6e-41 142.6 0.0 2.1 1 1 1 2 2 2 2 Vps53-like, N-terminal Vps54_N PF10475.9 KFM24563.1 - 8.9e-05 21.9 0.0 0.00014 21.3 0.0 1.1 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Spectrin PF00435.21 KFM24563.1 - 0.03 14.8 0.0 2 8.9 0.0 2.8 1 1 0 2 2 2 0 Spectrin repeat COG7 PF10191.9 KFM24563.1 - 0.04 12.2 0.0 0.048 11.9 0.0 1.1 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) DUF5082 PF16888.5 KFM24563.1 - 0.094 13.0 0.0 0.7 10.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) ARID PF01388.21 KFM24564.1 - 4.8e-13 49.6 0.0 8.6e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Glyco_transf_22 PF03901.17 KFM24565.1 - 2e-49 169.0 5.7 2.6e-49 168.6 5.7 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Pkinase PF00069.25 KFM24566.1 - 1.9e-43 148.7 0.0 2.8e-43 148.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM24566.1 - 4.4e-14 52.4 0.0 6.8e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM24566.1 - 7.4e-05 22.2 0.0 0.00013 21.4 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KFM24566.1 - 0.008 16.1 2.5 0.23 11.4 1.8 2.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFM24566.1 - 0.018 13.8 0.0 0.024 13.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pox_ser-thr_kin PF05445.11 KFM24566.1 - 0.02 13.9 0.0 0.029 13.3 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Ribosomal_L21e PF01157.18 KFM24567.1 - 3.9e-44 148.6 4.7 5.1e-44 148.2 4.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e Aconitase_C PF00694.19 KFM24568.1 - 7.9e-17 61.8 0.0 1.3e-16 61.1 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase_C PF00694.19 KFM24569.1 - 1.4e-15 57.8 0.0 2.3e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain RRM_1 PF00076.22 KFM24570.1 - 4.8e-20 71.2 0.1 8.2e-20 70.4 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF3g PF12353.8 KFM24570.1 - 9.1e-12 45.5 3.5 1.5e-11 44.7 3.5 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_occluded PF16842.5 KFM24570.1 - 0.087 12.7 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif SNF2_N PF00176.23 KFM24571.1 - 1.9e-47 161.7 0.0 1e-46 159.3 0.0 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFM24571.1 - 2.3e-17 63.3 0.0 3.9e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM24571.1 - 0.014 15.4 0.0 0.99 9.4 0.0 2.9 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_34 PF13872.6 KFM24571.1 - 0.043 12.7 0.1 0.31 9.9 0.1 2.1 1 1 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 HDA2-3 PF11496.8 KFM24571.1 - 0.15 11.2 0.0 0.42 9.7 0.0 1.7 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 Sec8_exocyst PF04048.14 KFM24572.1 - 1.3e-14 54.3 0.1 1.8e-14 53.8 0.1 1.2 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 KFM24572.1 - 0.00042 19.7 0.0 0.00051 19.4 0.0 1.1 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF4071 PF13281.6 KFM24572.1 - 0.023 13.7 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) SprT-like PF10263.9 KFM24573.1 - 7.6e-15 54.8 0.0 6.4e-14 51.8 0.0 2.0 2 0 0 2 2 2 1 SprT-like family Ribosomal_S27 PF01599.19 KFM24573.1 - 0.019 15.1 1.6 0.057 13.6 1.6 1.8 1 0 0 1 1 1 0 Ribosomal protein S27a WLM PF08325.10 KFM24573.1 - 0.15 12.1 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 WLM domain Synaptobrevin PF00957.21 KFM24574.1 - 4.9e-26 90.3 0.0 6.5e-26 90.0 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KFM24574.1 - 2.2e-19 69.3 0.0 3.3e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain RINGv PF12906.7 KFM24575.1 - 2.1e-07 31.0 9.9 3.1e-07 30.4 9.9 1.3 1 0 0 1 1 1 1 RING-variant domain TMEM208_SND2 PF05620.11 KFM24575.1 - 0.054 13.3 0.1 0.069 12.9 0.1 1.1 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 zf-RING_2 PF13639.6 KFM24575.1 - 0.11 12.9 8.5 0.14 12.5 7.5 1.7 2 0 0 2 2 2 0 Ring finger domain TGT PF01702.18 KFM24575.1 - 0.33 10.1 1.6 0.56 9.3 0.5 1.7 2 0 0 2 2 2 0 Queuine tRNA-ribosyltransferase Glyco_transf_41 PF13844.6 KFM24576.1 - 1.1e-84 284.5 1.0 8.7e-59 199.2 0.0 2.3 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_11 PF13414.6 KFM24576.1 - 2.8e-22 78.1 11.7 4.7e-08 32.6 0.7 5.6 4 1 1 5 5 5 5 TPR repeat TPR_1 PF00515.28 KFM24576.1 - 5.1e-22 76.7 12.3 2.8e-07 30.1 1.7 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 KFM24576.1 - 1.1e-15 56.4 3.7 7.4e-05 22.7 0.3 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFM24576.1 - 1.5e-14 52.8 16.2 2.5e-05 24.0 2.7 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 KFM24576.1 - 8.6e-12 45.2 19.8 2.1e-06 27.9 2.1 5.4 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFM24576.1 - 5.1e-11 41.8 10.0 0.004 17.1 0.2 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFM24576.1 - 2.2e-10 40.4 25.5 0.00052 20.6 2.3 6.5 4 2 2 6 6 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 KFM24576.1 - 3e-09 37.4 17.6 0.00038 21.0 3.2 4.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFM24576.1 - 1.4e-07 31.4 13.8 0.0026 18.0 0.9 7.3 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFM24576.1 - 3.4e-07 29.9 30.7 0.014 15.2 0.6 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_15 PF13429.6 KFM24576.1 - 2.9e-05 23.4 6.8 0.0032 16.7 0.9 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFM24576.1 - 0.0012 19.3 14.9 0.021 15.3 1.0 4.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFM24576.1 - 0.0013 19.2 12.2 2.3 9.0 0.2 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFM24576.1 - 0.0029 17.6 1.1 0.085 12.9 0.1 2.9 3 0 0 3 3 2 1 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.17 KFM24576.1 - 0.01 16.3 23.9 0.49 10.8 8.1 3.9 3 1 1 4 4 3 0 Bacterial transcriptional activator domain TPR_5 PF12688.7 KFM24576.1 - 0.085 13.1 9.7 0.042 14.1 1.2 3.2 2 2 1 3 3 3 0 Tetratrico peptide repeat TPR_9 PF13371.6 KFM24576.1 - 1.1 9.5 16.3 2 8.6 2.0 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 KFM24576.1 - 3.6 7.7 8.7 31 4.7 2.4 4.1 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain SnoaL PF07366.12 KFM24577.1 - 2.4e-07 30.6 0.0 3.6e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KFM24577.1 - 0.00037 21.1 0.0 0.00084 19.9 0.0 1.5 2 0 0 2 2 2 1 SnoaL-like domain Ribosomal_L44 PF00935.19 KFM24578.1 - 7.2e-36 122.5 13.3 1.3e-35 121.7 13.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L44 CD45 PF12567.8 KFM24578.1 - 0.0032 17.4 1.9 1.6 8.7 0.1 2.2 2 0 0 2 2 2 2 Leukocyte receptor CD45 Piwi PF02171.17 KFM24579.1 - 8.6e-68 228.8 0.0 1e-36 126.7 0.0 2.1 1 1 1 2 2 2 2 Piwi domain ArgoL1 PF08699.10 KFM24579.1 - 7.5e-15 54.3 0.0 1.9e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 KFM24579.1 - 2.7e-10 40.2 0.0 4.9e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 KFM24579.1 - 3.9e-09 36.7 0.0 1.1e-08 35.3 0.0 1.8 2 0 0 2 2 2 1 Argonaute linker 2 domain ArgoN PF16486.5 KFM24579.1 - 7.8e-08 33.0 0.0 1.5e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoMid PF16487.5 KFM24579.1 - 2.3e-07 31.0 0.0 7.2e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 Mid domain of argonaute Arm PF00514.23 KFM24580.1 - 1.2e-33 114.1 13.0 4e-07 29.8 0.0 8.0 9 0 0 9 9 9 6 Armadillo/beta-catenin-like repeat BTB PF00651.31 KFM24580.1 - 7.9e-22 77.6 0.0 3.9e-21 75.4 0.0 2.0 1 1 1 2 2 2 1 BTB/POZ domain HEAT PF02985.22 KFM24580.1 - 5.1e-11 41.8 5.4 0.02 15.1 0.1 6.8 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.6 KFM24580.1 - 4.7e-09 36.5 16.1 2.8e-05 24.4 0.2 5.9 5 2 4 9 9 9 5 HEAT repeats HEAT_EZ PF13513.6 KFM24580.1 - 0.00077 19.9 10.6 0.052 14.1 0.5 5.2 3 1 2 5 5 5 3 HEAT-like repeat Atx10homo_assoc PF09759.9 KFM24580.1 - 0.0067 16.4 0.0 4.7 7.3 0.0 3.2 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain Arm_2 PF04826.13 KFM24580.1 - 0.063 12.7 0.0 0.57 9.6 0.0 2.2 1 1 1 2 2 2 0 Armadillo-like Adaptin_N PF01602.20 KFM24580.1 - 0.12 10.9 0.0 0.53 8.8 0.0 2.1 1 1 1 2 2 2 0 Adaptin N terminal region Cnd1 PF12717.7 KFM24580.1 - 0.15 12.1 0.0 1.3 9.1 0.0 2.4 1 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.8 KFM24580.1 - 0.16 12.1 0.0 7.9 6.6 0.0 2.4 2 0 0 2 2 2 0 V-ATPase subunit H DUF5578 PF17741.1 KFM24580.1 - 0.16 11.4 0.1 0.58 9.5 0.1 1.9 1 1 0 1 1 1 0 Family of unknown function (DUF5578) V-ATPase_H_N PF03224.14 KFM24580.1 - 0.16 11.2 0.0 0.99 8.6 0.0 2.2 1 1 1 2 2 2 0 V-ATPase subunit H HEAT_PBS PF03130.16 KFM24580.1 - 2.4 9.1 16.9 67 4.6 0.1 7.5 8 0 0 8 8 6 0 PBS lyase HEAT-like repeat Glyco_hydro_9 PF00759.19 KFM24581.1 - 9.6e-107 357.9 12.9 1.3e-106 357.6 12.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 DPBB_1 PF03330.18 KFM24581.1 - 2e-05 24.8 0.2 5.2e-05 23.4 0.2 1.7 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KFM24581.1 - 0.0031 17.4 0.6 0.0084 16.0 0.6 1.8 1 0 0 1 1 1 1 Barwin family WD40 PF00400.32 KFM24582.1 - 0.066 14.1 0.3 0.65 11.0 0.5 2.6 2 0 0 2 2 2 0 WD domain, G-beta repeat Condensin2nSMC PF12422.8 KFM24583.1 - 1.2e-34 119.6 0.0 2.4e-34 118.7 0.0 1.5 1 0 0 1 1 1 1 Condensin II non structural maintenance of chromosomes subunit HEAT PF02985.22 KFM24583.1 - 7.5e-06 25.8 14.7 0.14 12.4 0.3 5.6 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.6 KFM24583.1 - 0.00019 21.8 22.3 0.0021 18.4 7.9 4.4 2 1 1 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 KFM24583.1 - 2.1 9.0 30.3 0.45 11.1 3.2 6.6 5 0 0 5 5 5 0 HEAT-like repeat CSS-motif PF12792.7 KFM24584.1 - 0.028 13.9 0.1 0.03 13.8 0.1 1.1 1 0 0 1 1 1 0 CSS motif domain associated with EAL ABC1 PF03109.16 KFM24585.1 - 3.5e-29 101.4 0.0 5.6e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 ABC1 family LRR_8 PF13855.6 KFM24586.1 - 4.2e-22 77.7 2.4 1.3e-10 40.9 0.0 3.5 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFM24586.1 - 4.4e-16 58.7 4.4 7.1e-05 23.1 0.1 4.7 1 1 4 6 6 6 6 Leucine Rich repeats (2 copies) Pkinase_Tyr PF07714.17 KFM24586.1 - 5.8e-14 52.0 0.0 2.3e-11 43.5 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KFM24586.1 - 2.8e-11 43.3 0.0 2.4e-10 40.2 0.0 1.9 1 1 1 2 2 2 1 Protein kinase domain LRR_1 PF00560.33 KFM24586.1 - 0.00012 22.2 7.9 13 6.8 0.1 6.6 7 1 0 7 7 7 1 Leucine Rich Repeat Kdo PF06293.14 KFM24586.1 - 0.00019 20.8 0.0 0.0003 20.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_9 PF14580.6 KFM24586.1 - 0.0022 17.5 0.4 2.6 7.5 0.1 3.4 1 1 2 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 KFM24586.1 - 0.099 12.8 4.5 23 5.4 0.0 4.8 5 0 0 5 5 5 0 Leucine Rich repeat GST_N_2 PF13409.6 KFM24587.1 - 4.8e-14 52.4 0.0 1.4e-10 41.3 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFM24587.1 - 1.6e-12 47.2 1.3 4e-12 46.0 1.3 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KFM24587.1 - 0.00012 22.4 0.0 0.67 10.4 0.0 3.1 2 1 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFM24587.1 - 0.00085 19.5 0.0 0.0029 17.8 0.0 1.7 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFM24587.1 - 0.034 14.3 0.0 0.058 13.6 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KFM24587.1 - 0.035 14.4 0.0 2.2 8.7 0.0 2.4 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Acetyltransf_7 PF13508.7 KFM24588.1 - 0.0019 18.6 0.0 0.004 17.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFM24588.1 - 0.0032 17.7 0.0 0.0063 16.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family GNAT_acetyltran PF12746.7 KFM24588.1 - 0.012 15.2 0.0 0.017 14.7 0.0 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase FR47 PF08445.10 KFM24588.1 - 0.038 14.0 0.0 0.083 12.9 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Arf PF00025.21 KFM24591.1 - 1e-62 210.7 0.0 1.6e-62 210.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Uricase PF01014.18 KFM24591.1 - 1.1e-48 164.8 0.2 1e-27 97.0 0.4 2.3 2 0 0 2 2 2 2 Uricase G-alpha PF00503.20 KFM24591.1 - 9.4e-11 41.5 0.1 1.8e-07 30.6 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KFM24591.1 - 2.3e-09 37.5 0.0 5.4e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KFM24591.1 - 1.6e-08 34.2 0.0 2.6e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KFM24591.1 - 5.1e-08 32.7 0.0 8.3e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KFM24591.1 - 1.1e-06 28.7 0.0 1.9e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFM24591.1 - 0.00016 21.1 0.0 0.00023 20.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 KFM24591.1 - 0.0078 16.0 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation CENP-M PF11111.8 KFM24591.1 - 0.015 14.5 0.0 0.053 12.7 0.0 1.8 2 0 0 2 2 2 0 Centromere protein M (CENP-M) UPF0029 PF01205.19 KFM24593.1 - 1.8e-22 79.6 0.0 2.7e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 KFM24593.1 - 5.1e-07 30.0 0.0 1e-06 29.0 0.0 1.4 1 1 0 1 1 1 1 RWD domain Cys_Met_Meta_PP PF01053.20 KFM24595.1 - 4.5e-131 436.9 0.0 5.1e-131 436.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KFM24595.1 - 7.7e-05 21.8 0.0 0.00014 21.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V GDC-P PF02347.16 KFM24595.1 - 0.15 10.9 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein RINT1_TIP1 PF04437.13 KFM24596.1 - 2e-13 50.1 0.0 4.7e-11 42.3 0.0 2.8 2 1 0 2 2 2 2 RINT-1 / TIP-1 family HBM PF16591.5 KFM24597.1 - 0.023 14.1 0.1 0.028 13.9 0.1 1.1 1 0 0 1 1 1 0 Helical bimodular sensor domain TH1 PF04858.13 KFM24598.1 - 2e-61 208.3 0.0 7.9e-34 117.2 0.0 3.0 2 1 1 3 3 3 3 TH1 protein AMP-binding PF00501.28 KFM24599.1 - 7.1e-99 331.3 0.0 1.4e-98 330.3 0.0 1.4 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFM24599.1 - 3.2e-06 28.0 1.2 2e-05 25.5 0.2 2.6 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Brix PF04427.18 KFM24600.1 - 1.1e-33 117.0 0.0 1.4e-33 116.7 0.0 1.1 1 0 0 1 1 1 1 Brix domain Steroid_dh PF02544.16 KFM24602.1 - 4.8e-52 175.9 0.1 7.5e-52 175.3 0.1 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KFM24602.1 - 0.00022 20.8 1.2 0.00031 20.4 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) Ribosomal_S27 PF01599.19 KFM24603.1 - 3e-25 88.1 1.7 5.6e-25 87.2 1.7 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a ubiquitin PF00240.23 KFM24603.1 - 5.2e-14 51.8 0.0 1.1e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S2 PF00318.20 KFM24603.1 - 0.0043 16.3 0.0 0.0053 16.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S2 Rad60-SLD PF11976.8 KFM24603.1 - 0.031 14.1 0.0 0.079 12.8 0.0 1.7 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like zf-C2H2_3 PF13878.6 KFM24603.1 - 0.032 14.0 1.2 0.88 9.4 0.2 2.4 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO Nudix_N_2 PF14803.6 KFM24603.1 - 0.2 11.6 3.2 0.87 9.6 0.3 2.4 2 0 0 2 2 2 0 Nudix N-terminal SAP PF02037.27 KFM24604.1 - 3.8e-13 48.8 1.2 3.8e-13 48.8 1.2 1.6 2 0 0 2 2 2 1 SAP domain RSB_motif PF16294.5 KFM24604.1 - 2.6e-11 43.7 2.5 1.9e-10 40.9 0.0 2.6 2 0 0 2 2 2 1 RNSP1-SAP18 binding (RSB) motif HeH PF12949.7 KFM24604.1 - 0.2 11.4 1.0 0.43 10.3 1.0 1.5 1 1 0 1 1 1 0 HeH/LEM domain Pinin_SDK_memA PF04696.13 KFM24604.1 - 0.76 9.8 2.8 4.9 7.2 0.0 2.3 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region Pes-10 PF07149.11 KFM24604.1 - 4.3 6.3 4.4 6.1 5.8 4.4 1.1 1 0 0 1 1 1 0 Pes-10 Myb_DNA-binding PF00249.31 KFM24606.1 - 6.5e-10 39.0 0.0 1.1e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain RNase_PH PF01138.21 KFM24608.1 - 3.7e-09 37.2 0.0 7.7e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KFM24608.1 - 3.5e-07 30.2 0.0 7.4e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Rad51 PF08423.11 KFM24610.1 - 1.9e-45 155.1 0.0 8.8e-45 152.9 0.0 1.8 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KFM24610.1 - 1.8e-12 47.2 3.1 3.7e-12 46.2 3.1 1.4 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KFM24610.1 - 3.1e-06 26.7 0.2 6.6e-06 25.6 0.2 1.6 1 1 0 1 1 1 1 KaiC RecA PF00154.21 KFM24610.1 - 0.072 12.5 1.4 0.29 10.5 0.1 2.0 2 0 0 2 2 2 0 recA bacterial DNA recombination protein Herpes_UL35 PF04496.12 KFM24610.1 - 2.1 8.7 5.3 0.6 10.4 0.7 2.2 2 0 0 2 2 2 0 Herpesvirus UL35 family PseudoU_synth_2 PF00849.22 KFM24611.1 - 4.4e-19 69.1 0.0 7.9e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase GRIM-19 PF06212.12 KFM24612.1 - 8e-33 113.2 0.2 9.5e-33 113.0 0.2 1.0 1 0 0 1 1 1 1 GRIM-19 protein p450 PF00067.22 KFM24613.1 - 6.1e-85 285.7 0.0 7.7e-85 285.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_16 PF10294.9 KFM24614.1 - 8e-18 64.8 0.0 1.3e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 KFM24614.1 - 1.9e-07 30.8 0.1 3.3e-07 30.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KFM24614.1 - 5.6e-07 29.3 0.2 1.2e-06 28.2 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KFM24614.1 - 5.6e-06 27.0 0.1 1.8e-05 25.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFM24614.1 - 0.0023 18.5 0.4 0.0066 17.1 0.1 1.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM24614.1 - 0.004 17.0 0.0 0.0076 16.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM24614.1 - 0.0072 17.1 0.0 0.015 16.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KFM24614.1 - 0.018 14.7 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_23 PF13489.6 KFM24614.1 - 0.047 13.5 0.0 0.091 12.6 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 KFM24614.1 - 0.3 10.0 0.0 0.44 9.5 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase PseudoU_synth_1 PF01416.20 KFM24615.1 - 1.1e-16 61.3 0.0 5.2e-13 49.4 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase UQ_con PF00179.26 KFM24616.1 - 6.9e-16 58.2 0.0 1e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PGAP1 PF07819.13 KFM24617.1 - 2.7e-06 27.3 0.1 3.6e-06 26.9 0.1 1.1 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 KFM24617.1 - 8.5e-06 25.4 0.1 1.2e-05 25.0 0.1 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 KFM24617.1 - 3.1e-05 23.9 0.0 4.2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 KFM24617.1 - 0.00048 20.8 3.8 0.00053 20.7 3.6 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.15 KFM24617.1 - 0.005 16.1 0.0 0.0065 15.7 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_3 PF07859.13 KFM24617.1 - 0.018 14.9 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_8 PF06259.12 KFM24617.1 - 0.12 12.0 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Hydrolase_4 PF12146.8 KFM24617.1 - 0.12 11.6 0.1 0.18 11.1 0.1 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF915 PF06028.11 KFM24617.1 - 0.32 10.3 0.0 0.41 9.9 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Syntaxin-6_N PF09177.11 KFM24618.1 - 5.7e-15 55.7 2.4 1.1e-14 54.7 0.5 2.1 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 KFM24618.1 - 3e-08 33.5 0.9 5.7e-08 32.6 0.1 1.9 2 0 0 2 2 2 1 SNARE domain NPV_P10 PF05531.12 KFM24618.1 - 0.08 13.4 0.2 8 7.0 0.0 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein SesA PF17107.5 KFM24618.1 - 0.1 12.8 0.4 0.78 9.9 0.1 2.2 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases UPF0242 PF06785.11 KFM24618.1 - 0.11 12.6 0.4 2.9 8.0 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus UPF0449 PF15136.6 KFM24618.1 - 0.37 11.3 2.1 0.83 10.2 0.1 2.2 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 DUF4164 PF13747.6 KFM24618.1 - 0.47 10.8 8.5 1.9 8.8 0.8 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) DUF3040 PF11239.8 KFM24618.1 - 1.4 9.2 6.2 0.57 10.5 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Activator-TraM PF11657.8 KFM24618.1 - 1.5 8.7 6.5 1.8 8.4 0.0 3.2 2 1 1 3 3 3 0 Transcriptional activator TraM Ank_2 PF12796.7 KFM24619.1 - 4.9e-19 68.7 2.4 4.7e-12 46.3 0.5 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM24619.1 - 4.9e-18 65.2 4.2 2e-11 44.2 0.1 3.6 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM24619.1 - 1.4e-16 58.9 8.9 0.00029 21.0 0.0 5.5 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 KFM24619.1 - 9e-16 57.5 14.4 3.7e-05 24.0 0.0 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 KFM24619.1 - 2.8e-13 49.8 8.1 2.1e-08 34.3 0.6 4.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) DUF1843 PF08898.10 KFM24619.1 - 0.03 14.8 3.0 15 6.2 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) SRP-alpha_N PF04086.13 KFM24619.1 - 3 7.7 6.2 4.2 7.2 6.2 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Trypsin_2 PF13365.6 KFM24620.1 - 9.5e-25 88.2 3.8 2.8e-21 77.0 1.2 2.6 2 0 0 2 2 2 2 Trypsin-like peptidase domain Trypsin PF00089.26 KFM24620.1 - 2.9e-09 37.1 0.0 4.4e-08 33.2 0.0 2.1 1 1 1 2 2 2 1 Trypsin PDZ_6 PF17820.1 KFM24620.1 - 6.7e-06 25.9 0.3 1.9e-05 24.4 0.3 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFM24620.1 - 0.0035 17.6 0.0 0.0074 16.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Peptidase_S29 PF02907.15 KFM24620.1 - 0.097 12.4 1.3 0.54 10.0 0.0 2.4 2 1 0 2 2 2 0 Hepatitis C virus NS3 protease Peptidase_S46 PF10459.9 KFM24620.1 - 0.19 10.3 0.5 0.27 9.8 0.1 1.4 2 0 0 2 2 2 0 Peptidase S46 RRF PF01765.19 KFM24622.1 - 7.7e-57 191.8 2.4 8.1e-57 191.7 0.4 1.8 1 1 1 2 2 2 1 Ribosome recycling factor CCDC-167 PF15188.6 KFM24622.1 - 1.8 8.9 9.4 2.3 8.6 3.4 2.8 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 HI0933_like PF03486.14 KFM24623.1 - 7.3e-43 146.8 0.0 6.2e-22 77.9 0.0 3.1 2 1 1 3 3 3 3 HI0933-like protein FAD_binding_2 PF00890.24 KFM24623.1 - 9.1e-10 38.2 2.4 2.7e-09 36.6 2.0 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KFM24623.1 - 3.2e-09 36.9 0.2 9.6e-09 35.4 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFM24623.1 - 5.8e-07 29.0 0.1 9.5e-07 28.3 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFM24623.1 - 1e-06 28.6 3.3 1.7e-06 27.9 3.3 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KFM24623.1 - 2.6e-06 26.9 0.1 4.5e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KFM24623.1 - 2.9e-05 23.3 2.0 4.5e-05 22.7 2.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 KFM24623.1 - 0.00018 22.0 0.8 0.00096 19.7 0.3 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFM24623.1 - 0.00029 20.2 0.3 0.0007 18.9 0.3 1.6 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 KFM24623.1 - 0.00061 19.2 2.6 0.00061 19.2 2.6 2.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KFM24623.1 - 0.00063 20.1 0.1 0.0014 19.0 0.1 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding 3HCDH_N PF02737.18 KFM24623.1 - 0.00063 19.7 0.8 0.0011 18.9 0.8 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 KFM24623.1 - 0.0011 18.2 0.1 0.0018 17.6 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KFM24623.1 - 0.0033 16.7 0.3 0.0053 16.1 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KFM24623.1 - 0.0072 15.7 0.2 0.013 14.9 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 KFM24623.1 - 0.034 13.8 0.2 0.076 12.7 0.2 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 KFM24623.1 - 0.047 13.9 0.3 0.14 12.3 0.0 2.0 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 KFM24623.1 - 0.086 12.9 0.1 0.15 12.1 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FMO-like PF00743.19 KFM24623.1 - 0.1 11.0 0.2 0.2 10.0 0.0 1.5 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like Guanylate_kin PF00625.21 KFM24624.1 - 8.3e-21 74.5 0.1 2.5e-16 59.9 0.0 2.2 1 1 1 2 2 2 2 Guanylate kinase AAA_16 PF13191.6 KFM24624.1 - 0.00022 21.6 0.0 0.0016 18.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain S1 PF00575.23 KFM24625.1 - 2.8e-15 56.4 3.2 6e-10 39.3 0.4 2.2 2 0 0 2 2 2 2 S1 RNA binding domain PUA PF01472.20 KFM24625.1 - 0.0029 17.5 0.3 0.016 15.2 0.0 2.2 2 1 1 3 3 3 1 PUA domain Pkinase PF00069.25 KFM24626.1 - 1.4e-72 244.2 0.0 1.7e-72 244.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM24626.1 - 9.8e-32 110.2 0.0 1.3e-31 109.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM24626.1 - 4.7e-05 22.8 0.0 0.0011 18.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like IPTL-CTERM PF18203.1 KFM24626.1 - 0.018 14.9 0.5 1 9.4 0.0 2.7 2 0 0 2 2 2 0 IPTL-CTERM motif APH PF01636.23 KFM24626.1 - 0.045 13.7 0.2 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFM24626.1 - 0.23 10.4 0.0 0.68 8.8 0.0 1.6 2 0 0 2 2 2 0 Haspin like kinase domain HEAT PF02985.22 KFM24627.1 - 1.2e-34 115.4 37.0 1.2e-05 25.1 0.1 12.9 14 0 0 14 14 14 9 HEAT repeat HEAT_2 PF13646.6 KFM24627.1 - 5.1e-26 90.9 29.2 3.6e-07 30.5 0.5 6.8 2 2 1 5 5 5 5 HEAT repeats Vac14_Fab1_bd PF12755.7 KFM24627.1 - 7.5e-09 36.1 0.0 0.48 11.1 0.0 6.2 4 3 3 8 8 8 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 KFM24627.1 - 1e-08 34.2 0.7 0.0021 16.7 0.2 4.4 1 1 2 3 3 3 2 Adaptin N terminal region HEAT_EZ PF13513.6 KFM24627.1 - 4.9e-08 33.3 30.5 0.0014 19.1 0.1 8.5 6 3 3 9 9 9 3 HEAT-like repeat Cnd1 PF12717.7 KFM24627.1 - 9.7e-08 32.2 0.4 0.16 12.0 0.4 4.6 3 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 DNA_alkylation PF08713.11 KFM24627.1 - 0.00031 20.5 0.3 0.097 12.4 0.3 3.1 2 1 0 2 2 2 1 DNA alkylation repair enzyme CitMHS PF03600.16 KFM24627.1 - 0.032 13.4 0.0 2.4 7.3 0.0 2.3 2 0 0 2 2 2 0 Citrate transporter HEAT_PBS PF03130.16 KFM24627.1 - 8.6 7.4 15.8 1.6 9.6 0.1 6.5 7 0 0 7 7 7 0 PBS lyase HEAT-like repeat Thioredoxin PF00085.20 KFM24628.1 - 7.2e-28 96.6 0.1 8.7e-28 96.3 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KFM24628.1 - 4.3e-07 30.4 0.1 3.7e-06 27.3 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KFM24628.1 - 2.5e-06 27.7 0.5 2.2e-05 24.7 0.1 2.4 3 1 1 4 4 4 1 Thioredoxin-like Redoxin PF08534.10 KFM24628.1 - 5.6e-06 26.1 0.2 0.00013 21.7 0.1 2.2 1 1 1 2 2 2 1 Redoxin Thioredoxin_7 PF13899.6 KFM24628.1 - 9.9e-06 25.7 0.2 2.5e-05 24.4 0.2 1.7 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 KFM24628.1 - 1.6e-05 24.8 0.1 2.7e-05 24.1 0.1 1.6 1 1 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 KFM24628.1 - 1.8e-05 24.2 0.0 1.9e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family TraF PF13728.6 KFM24628.1 - 0.0056 16.5 0.0 0.0058 16.5 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 KFM24628.1 - 0.013 15.3 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin PF00085.20 KFM24629.1 - 1.3e-16 60.5 0.0 1.5e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KFM24629.1 - 3.4e-05 24.3 0.3 0.00044 20.7 0.3 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KFM24629.1 - 0.0004 20.6 0.0 0.11 12.8 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 KFM24629.1 - 0.014 14.8 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 KFM24629.1 - 0.014 15.6 0.2 0.037 14.2 0.1 1.7 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_9 PF14595.6 KFM24629.1 - 0.044 13.6 0.0 0.048 13.4 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_4 PF13462.6 KFM24629.1 - 0.063 13.4 0.0 2.9 8.0 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin Thioredoxin_5 PF13743.6 KFM24629.1 - 0.08 12.6 0.0 7.8 6.1 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin HyaE PF07449.11 KFM24629.1 - 0.13 12.3 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin PF00085.20 KFM24630.1 - 1.7e-17 63.3 0.2 2.4e-17 62.8 0.2 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KFM24630.1 - 8.6e-06 26.0 0.1 0.002 18.4 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.6 KFM24630.1 - 0.00079 19.2 0.1 0.001 18.8 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 KFM24630.1 - 0.0011 19.1 0.4 0.0019 18.3 0.4 1.4 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 KFM24630.1 - 0.0014 18.1 0.1 0.0031 16.9 0.0 1.5 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KFM24630.1 - 0.0026 18.2 0.1 0.0076 16.7 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 KFM24630.1 - 0.057 13.3 0.1 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 AhpC/TSA family Piezo_RRas_bdg PF12166.8 KFM24630.1 - 0.13 11.5 0.1 0.15 11.3 0.1 1.2 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain Abhydrolase_1 PF00561.20 KFM24631.1 - 2e-05 24.4 0.0 2.3e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 KFM24631.1 - 0.0043 16.8 0.0 0.0054 16.5 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 KFM24631.1 - 0.024 14.5 0.0 0.025 14.4 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Hydrolase_4 PF12146.8 KFM24631.1 - 0.03 13.6 0.0 0.033 13.4 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PPR_2 PF13041.6 KFM24632.1 - 7.6e-40 134.9 0.0 4.9e-07 29.8 0.0 10.1 7 2 4 11 11 11 9 PPR repeat family PPR PF01535.20 KFM24632.1 - 1.3e-35 119.2 3.0 1.7e-05 24.7 0.0 11.2 11 0 0 11 11 11 6 PPR repeat PPR_3 PF13812.6 KFM24632.1 - 1.6e-20 72.9 0.0 0.00064 19.8 0.0 8.5 7 2 4 11 11 11 5 Pentatricopeptide repeat domain PPR_1 PF12854.7 KFM24632.1 - 1.5e-19 69.4 0.0 2.9e-05 23.6 0.0 7.8 8 0 0 8 8 8 4 PPR repeat PPR_long PF17177.4 KFM24632.1 - 2.8e-10 39.9 0.0 0.0095 15.3 0.0 5.1 4 1 1 5 5 5 3 Pentacotripeptide-repeat region of PRORP TPR_7 PF13176.6 KFM24632.1 - 0.0006 19.7 1.6 21 5.4 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat AMMECR1 PF01871.17 KFM24632.1 - 0.068 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 AMMECR1 TPR_14 PF13428.6 KFM24632.1 - 2.4 9.2 21.2 52 5.0 0.0 8.5 4 3 6 10 10 10 0 Tetratricopeptide repeat Proteasome PF00227.26 KFM24633.1 - 1.8e-35 122.1 0.0 2.2e-35 121.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit CBS PF00571.28 KFM24633.1 - 0.11 13.0 0.2 0.97 9.9 0.0 2.2 2 0 0 2 2 2 0 CBS domain R3H-assoc PF13902.6 KFM24634.1 - 8.5e-07 29.4 0.0 1.4e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.22 KFM24634.1 - 6.7e-05 22.8 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 R3H domain DUF3236 PF11576.8 KFM24634.1 - 0.26 11.0 0.0 0.44 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3236) Pkinase PF00069.25 KFM24635.1 - 1e-41 143.1 0.0 1.6e-34 119.5 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFM24635.1 - 1.3e-15 57.4 0.0 2e-09 37.1 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase Bud13 PF09736.9 KFM24635.1 - 4.1e-13 50.0 2.9 4.1e-13 50.0 2.9 2.2 2 0 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex Kinase-like PF14531.6 KFM24635.1 - 0.00031 20.2 0.0 0.00059 19.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RWD PF05773.22 KFM24635.1 - 0.048 13.9 0.0 0.075 13.3 0.0 1.3 1 0 0 1 1 1 0 RWD domain Kdo PF06293.14 KFM24635.1 - 0.061 12.7 0.1 0.28 10.5 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KFM24637.1 - 3.9e-36 124.8 0.0 1.3e-35 123.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM24637.1 - 7.1e-36 123.8 0.0 4e-35 121.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Peptidase_S8 PF00082.22 KFM24637.1 - 5e-08 32.6 0.3 2.5e-07 30.2 0.3 2.0 1 1 0 1 1 1 1 Subtilase family Kinase-like PF14531.6 KFM24637.1 - 0.047 13.0 0.0 0.076 12.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.25 KFM24640.1 - 2.8e-50 171.2 0.0 8.2e-50 169.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM24640.1 - 1.3e-45 155.7 0.0 6.2e-45 153.5 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Peptidase_S8 PF00082.22 KFM24640.1 - 7.5e-05 22.1 1.1 0.00042 19.7 1.1 2.1 1 1 0 1 1 1 1 Subtilase family Pkinase_fungal PF17667.1 KFM24640.1 - 0.0093 14.8 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFM24640.1 - 0.16 11.3 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like AIRC PF00731.20 KFM24641.1 - 2.4e-51 173.2 3.2 2.4e-51 173.2 3.2 2.1 2 0 0 2 2 2 1 AIR carboxylase ATP-grasp PF02222.22 KFM24641.1 - 1.3e-46 158.4 0.0 2.1e-46 157.6 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 KFM24641.1 - 2.4e-17 62.4 0.0 4.8e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 KFM24641.1 - 0.0027 17.2 0.8 0.0074 15.8 0.1 2.1 2 1 1 3 3 3 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ArgJ PF01960.18 KFM24643.1 - 3.4e-117 391.4 3.4 8.9e-106 353.8 1.5 2.1 1 1 1 2 2 2 2 ArgJ family Biopterin_H PF00351.21 KFM24644.1 - 9e-102 340.5 0.0 1.2e-101 340.1 0.0 1.0 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase HhH-GPD PF00730.25 KFM24644.1 - 0.096 13.2 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein C2 PF00168.30 KFM24646.1 - 1.3e-13 51.1 0.0 2.5e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 C2 domain DUF751 PF05421.11 KFM24647.1 - 7e-17 61.9 5.5 1.2e-16 61.1 5.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF751) Elong-fact-P_C PF09285.11 KFM24648.1 - 1.1e-20 73.1 0.7 2.5e-20 71.9 0.7 1.6 1 0 0 1 1 1 1 Elongation factor P, C-terminal EFP PF01132.20 KFM24648.1 - 1.4e-14 53.9 0.0 2.2e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain EFP_N PF08207.12 KFM24648.1 - 6e-11 42.2 0.0 9.6e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Peroxin-3 PF04882.12 KFM24650.1 - 7.1e-12 45.1 1.0 2.2e-10 40.2 0.1 2.8 1 1 1 3 3 3 1 Peroxin-3 DUF2997 PF11211.8 KFM24650.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2997) Ammonium_transp PF00909.21 KFM24651.1 - 1.7e-107 359.5 33.1 2.1e-107 359.3 33.1 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family DUF5479 PF17575.2 KFM24651.1 - 0.041 14.4 0.0 0.45 11.1 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5479) 14-3-3 PF00244.20 KFM24653.1 - 1.3e-28 100.1 5.1 1.4e-28 99.9 5.1 1.0 1 0 0 1 1 1 1 14-3-3 protein DASH_Dad4 PF08650.10 KFM24653.1 - 0.015 15.2 1.2 0.04 13.9 0.1 1.9 2 0 0 2 2 2 0 DASH complex subunit Dad4 NDUF_B6 PF09782.9 KFM24653.1 - 0.073 13.2 0.2 0.08 13.1 0.2 1.2 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit UQ_con PF00179.26 KFM24655.1 - 3.5e-47 159.6 0.0 4e-47 159.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KFM24655.1 - 0.005 16.7 0.1 0.0097 15.8 0.1 1.5 1 1 0 1 1 1 1 UEV domain Prok-E2_B PF14461.6 KFM24655.1 - 0.019 14.7 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 KFM24655.1 - 0.17 12.2 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 RWD domain AA_permease_2 PF13520.6 KFM24657.1 - 6.4e-36 124.1 35.0 6.4e-36 124.1 35.0 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFM24657.1 - 1.6e-21 76.5 31.2 1.6e-21 76.5 31.2 1.8 2 0 0 2 2 2 1 Amino acid permease Tom7 PF08038.12 KFM24657.1 - 0.056 13.1 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 TOM7 family VEGFR-2_TMD PF17988.1 KFM24657.1 - 4.2 6.9 5.4 13 5.3 1.9 2.8 2 0 0 2 2 2 0 VEGFR-2 Transmembrane domain AA_permease_2 PF13520.6 KFM24658.1 - 7.5e-32 110.7 27.6 7.5e-32 110.7 27.6 1.7 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.21 KFM24658.1 - 1.3e-15 57.0 29.6 3.3e-15 55.6 29.7 1.7 1 1 0 1 1 1 1 Amino acid permease PSII_Ycf12 PF05969.11 KFM24658.1 - 3 7.9 7.5 0.37 10.8 1.0 2.9 3 0 0 3 3 3 0 Photosystem II complex subunit Ycf12 Smr PF01713.21 KFM24659.1 - 0.00029 21.2 0.3 0.0054 17.0 0.1 2.7 1 1 1 2 2 2 1 Smr domain PPR_2 PF13041.6 KFM24659.1 - 0.0006 20.0 0.0 3.9 7.8 0.0 3.5 3 1 0 3 3 3 2 PPR repeat family PPR PF01535.20 KFM24659.1 - 0.023 14.9 0.1 22 5.6 0.0 4.5 6 0 0 6 6 6 0 PPR repeat DUF3291 PF11695.8 KFM24659.1 - 0.19 11.4 0.0 0.6 9.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3291) SHS2_Rpb7-N PF03876.17 KFM24660.1 - 6.1e-16 58.5 0.0 9.6e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 KFM24660.1 - 1.8e-09 37.8 0.0 3e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain Tugs PF17840.1 KFM24660.1 - 0.033 14.4 0.0 0.061 13.5 0.0 1.4 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain FAE1_CUT1_RppA PF08392.12 KFM24661.1 - 1.4e-134 447.9 0.0 2e-134 447.5 0.0 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein LsmAD PF06741.13 KFM24661.1 - 2.2e-16 60.1 0.0 4.3e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 LsmAD domain ACP_syn_III_C PF08541.10 KFM24661.1 - 1e-11 44.8 0.0 4.3e-11 42.8 0.0 2.0 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Chal_sti_synt_C PF02797.15 KFM24661.1 - 7.6e-11 42.2 0.0 1.4e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain SM-ATX PF14438.6 KFM24661.1 - 1.5e-09 37.9 0.0 2.7e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain Chal_sti_synt_N PF00195.19 KFM24661.1 - 0.0065 15.9 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain ACP_syn_III PF08545.10 KFM24661.1 - 0.011 15.6 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Abhydrolase_1 PF00561.20 KFM24662.1 - 2.6e-12 46.9 0.0 9e-09 35.3 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFM24662.1 - 3.5e-07 29.8 0.0 0.015 14.6 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFM24662.1 - 8.1e-06 26.6 42.9 8.1e-06 26.6 42.9 3.2 2 2 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 KFM24662.1 - 0.051 13.7 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Sedlin_N PF04628.13 KFM24663.1 - 1e-38 132.4 0.2 1.1e-38 132.3 0.2 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 KFM24663.1 - 7.5e-09 35.6 0.1 8.7e-09 35.4 0.1 1.2 1 1 0 1 1 1 1 Sybindin-like family EMP70 PF02990.16 KFM24664.1 - 8.5e-201 668.1 0.0 8.5e-201 668.1 0.0 1.3 2 0 0 2 2 2 1 Endomembrane protein 70 RNase_PH PF01138.21 KFM24665.1 - 9.3e-19 68.2 0.0 2.4e-09 37.8 0.0 2.4 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 KH_1 PF00013.29 KFM24665.1 - 6.7e-10 38.7 0.0 1.2e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 KH domain S1 PF00575.23 KFM24665.1 - 1.3e-08 35.0 0.0 2.4e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain KH_2 PF07650.17 KFM24665.1 - 0.018 14.8 0.0 0.041 13.7 0.0 1.5 1 0 0 1 1 1 0 KH domain RNase_PH_C PF03725.15 KFM24665.1 - 0.035 14.1 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 3' exoribonuclease family, domain 2 ST7 PF04184.12 KFM24665.1 - 0.27 9.7 0.0 0.42 9.0 0.0 1.2 1 0 0 1 1 1 0 ST7 protein dsDNA_bind PF01984.20 KFM24666.1 - 9.2e-31 106.4 19.1 1.1e-30 106.2 19.1 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Cupin_2 PF07883.11 KFM24667.1 - 6.8e-15 54.5 0.1 2.9e-06 26.9 0.0 2.2 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 KFM24667.1 - 1.8e-07 31.1 0.2 0.0003 20.7 0.1 2.2 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_6 PF12852.7 KFM24667.1 - 0.00076 19.2 0.0 0.0015 18.3 0.0 1.4 1 1 0 1 1 1 1 Cupin Cupin_3 PF05899.12 KFM24667.1 - 0.00096 18.8 0.0 0.012 15.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF861) Herpes_UL52 PF03121.15 KFM24669.1 - 4e-08 33.1 0.3 9.3e-08 31.9 0.3 1.6 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase B-block_TFIIIC PF04182.12 KFM24670.1 - 1.6e-12 47.4 0.0 1.5e-11 44.2 0.0 2.3 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC HTH_27 PF13463.6 KFM24670.1 - 6.3e-05 23.4 0.4 0.24 11.9 0.0 3.5 3 0 0 3 3 3 2 Winged helix DNA-binding domain HTH_20 PF12840.7 KFM24670.1 - 0.00089 19.3 8.0 0.05 13.7 0.8 4.5 4 0 0 4 4 4 1 Helix-turn-helix domain AF-4 PF05110.13 KFM24670.1 - 0.0056 14.8 3.7 0.0078 14.4 3.7 1.2 1 0 0 1 1 1 1 AF-4 proto-oncoprotein YdaS_antitoxin PF15943.5 KFM24670.1 - 0.0066 16.3 0.0 0.25 11.2 0.0 2.6 2 0 0 2 2 2 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT MarR_2 PF12802.7 KFM24670.1 - 0.019 14.8 9.5 0.16 11.8 0.1 4.6 4 0 0 4 4 4 0 MarR family MarR PF01047.22 KFM24670.1 - 0.025 14.5 0.1 0.18 11.7 0.0 2.5 2 0 0 2 2 2 0 MarR family SIS PF01380.22 KFM24672.1 - 1.4e-15 57.3 0.0 2.1e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 SIS domain CBS PF00571.28 KFM24672.1 - 4.5e-15 55.8 1.4 3.6e-07 30.5 0.1 3.3 3 0 0 3 3 3 2 CBS domain SIS_2 PF13580.6 KFM24672.1 - 5e-06 26.6 0.0 0.0036 17.3 0.0 2.4 1 1 1 2 2 2 2 SIS domain DEAD PF00270.29 KFM24672.1 - 0.013 15.3 0.1 0.025 14.3 0.1 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase DUF2529 PF10740.9 KFM24672.1 - 0.045 13.4 0.0 0.086 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2529) CIDE-N PF02017.15 KFM24672.1 - 0.099 12.7 0.0 13 5.9 0.0 2.5 2 0 0 2 2 2 0 CIDE-N domain AAA_34 PF13872.6 KFM24672.1 - 0.1 11.4 0.0 0.57 9.0 0.0 1.9 2 0 0 2 2 2 0 P-loop containing NTP hydrolase pore-1 Ribosomal_L22 PF00237.19 KFM24673.1 - 3.4e-20 72.2 0.4 5.9e-20 71.4 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DEAD PF00270.29 KFM24674.1 - 4.6e-25 88.4 0.0 1.4e-24 86.8 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM24674.1 - 2.2e-21 76.3 0.0 5.5e-21 75.0 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM24674.1 - 4.1e-05 23.7 0.0 6.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Thioredoxin PF00085.20 KFM24676.1 - 7.5e-24 83.7 0.1 8.5e-24 83.5 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KFM24676.1 - 1.4e-07 31.9 0.1 5.6e-07 30.0 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KFM24676.1 - 0.00027 21.2 0.0 0.009 16.3 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 KFM24676.1 - 0.0006 19.7 0.1 0.00075 19.4 0.1 1.4 1 1 0 1 1 1 1 AhpC/TSA family Phosducin PF02114.16 KFM24676.1 - 0.003 16.5 0.0 0.0036 16.3 0.0 1.0 1 0 0 1 1 1 1 Phosducin Thioredoxin_7 PF13899.6 KFM24676.1 - 0.0053 16.9 0.0 0.0073 16.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 KFM24676.1 - 0.058 13.2 0.0 0.064 13.0 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin HyaE PF07449.11 KFM24676.1 - 0.064 13.2 0.0 0.11 12.5 0.0 1.5 1 1 0 1 1 1 0 Hydrogenase-1 expression protein HyaE IU_nuc_hydro PF01156.19 KFM24677.1 - 1.5e-64 218.4 0.1 3.6e-63 213.9 0.1 2.0 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Aldo_ket_red PF00248.21 KFM24679.1 - 1.2e-48 165.8 0.0 1.6e-48 165.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family ABC_membrane PF00664.23 KFM24680.1 - 1e-21 77.8 0.7 1.4e-21 77.4 0.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KFM24680.1 - 1.3e-18 67.9 0.0 4.1e-18 66.2 0.0 1.8 2 0 0 2 2 1 1 ABC transporter AAA_16 PF13191.6 KFM24680.1 - 0.00014 22.3 0.1 0.00043 20.7 0.0 1.9 2 0 0 2 2 1 1 AAA ATPase domain AAA_21 PF13304.6 KFM24680.1 - 0.00021 21.2 0.0 0.00031 20.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFM24680.1 - 0.00055 19.6 0.1 0.0014 18.3 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KFM24680.1 - 0.0009 19.5 0.0 0.0021 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFM24680.1 - 0.00095 19.7 0.0 0.0058 17.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain Rad17 PF03215.15 KFM24680.1 - 0.0059 16.5 0.0 0.0091 15.9 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain CENP-L PF13092.6 KFM24680.1 - 0.011 16.0 0.0 0.028 14.7 0.0 1.7 1 0 0 1 1 1 0 Kinetochore complex Sim4 subunit Fta1 AAA_30 PF13604.6 KFM24680.1 - 0.012 15.4 0.0 0.026 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KFM24680.1 - 0.024 13.9 0.0 0.049 12.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.14 KFM24680.1 - 0.024 14.6 0.0 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 KFM24680.1 - 0.025 15.1 0.0 0.052 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 KFM24680.1 - 0.026 14.3 0.1 0.073 12.8 0.1 1.8 1 0 0 1 1 1 0 Cytidylate kinase T2SSE PF00437.20 KFM24680.1 - 0.029 13.4 0.0 0.043 12.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein PRK PF00485.18 KFM24680.1 - 0.031 14.0 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Get5_C PF18514.1 KFM24680.1 - 0.044 13.5 0.1 0.12 12.1 0.1 1.7 1 0 0 1 1 1 0 Get5 C-terminal domain ATPase_2 PF01637.18 KFM24680.1 - 0.049 13.5 0.0 0.099 12.5 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 KFM24680.1 - 0.05 13.7 0.2 0.19 11.8 0.0 2.1 2 0 0 2 2 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 KFM24680.1 - 0.053 13.7 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KFM24680.1 - 0.054 13.4 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase NTPase_1 PF03266.15 KFM24680.1 - 0.061 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 NTPase DUF87 PF01935.17 KFM24680.1 - 0.073 13.2 0.2 0.13 12.4 0.2 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_15 PF13175.6 KFM24680.1 - 0.085 12.6 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 KFM24680.1 - 0.1 13.0 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase APS_kinase PF01583.20 KFM24680.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase cobW PF02492.19 KFM24680.1 - 0.14 11.7 0.0 0.35 10.4 0.0 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 KFM24680.1 - 0.16 11.9 0.0 3.4 7.6 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.6 KFM24680.1 - 0.16 11.6 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain T4SS_TraI PF16932.5 KFM24680.1 - 0.17 11.0 1.5 0.4 9.8 1.5 1.6 1 0 0 1 1 1 0 Type IV secretory system, conjugal DNA-protein transfer Vps16_N PF04841.13 KFM24681.1 - 1.5e-36 126.1 0.0 8.4e-22 77.5 0.0 3.0 2 1 1 3 3 3 3 Vps16, N-terminal region Vps16_C PF04840.12 KFM24681.1 - 2.3e-21 76.2 0.0 8.6e-21 74.3 0.0 1.7 1 1 0 1 1 1 1 Vps16, C-terminal region Ribosomal_S9 PF00380.19 KFM24682.1 - 2.5e-47 160.4 0.1 4.4e-47 159.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Mad3_BUB1_I PF08311.12 KFM24682.1 - 6.6e-39 132.7 0.0 1.1e-38 132.1 0.0 1.3 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 PGI PF00342.19 KFM24683.1 - 1.2e-199 664.0 0.0 1.4e-199 663.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase DUF4105 PF13387.6 KFM24683.1 - 0.043 13.4 0.0 0.075 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) P_proprotein PF01483.20 KFM24684.1 - 0.00065 19.7 0.3 0.18 11.9 0.1 2.4 2 0 0 2 2 2 2 Proprotein convertase P-domain AflR PF08493.10 KFM24684.1 - 0.0084 15.6 2.4 0.02 14.4 2.4 1.6 1 0 0 1 1 1 1 Aflatoxin regulatory protein TPPII_N PF12583.8 KFM24684.1 - 0.88 10.1 7.7 2.2 8.9 5.8 2.4 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal SRP54 PF00448.22 KFM24685.1 - 6.2e-78 260.9 0.9 1e-77 260.2 0.9 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 KFM24685.1 - 5.1e-28 97.6 3.2 5.1e-28 97.6 3.2 3.0 4 0 0 4 4 2 1 Signal peptide binding domain SRP54_N PF02881.19 KFM24685.1 - 3.3e-19 68.9 1.1 3.3e-19 68.9 1.1 2.0 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain cobW PF02492.19 KFM24685.1 - 5.1e-06 26.2 0.1 2.3e-05 24.1 0.0 2.0 2 1 0 2 2 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 KFM24685.1 - 8.3e-06 26.3 0.0 2e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 KFM24685.1 - 1.6e-05 24.8 0.2 3.8e-05 23.5 0.2 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFM24685.1 - 2.2e-05 24.6 0.1 0.00011 22.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KFM24685.1 - 0.00011 22.7 0.0 0.00044 20.7 0.0 2.1 1 0 0 1 1 1 1 AAA domain CLP1_P PF16575.5 KFM24685.1 - 0.0015 18.3 0.0 0.17 11.6 0.0 2.5 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_22 PF13401.6 KFM24685.1 - 0.0017 18.7 0.1 0.011 16.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KFM24685.1 - 0.0023 18.0 0.3 0.022 14.9 0.3 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Zeta_toxin PF06414.12 KFM24685.1 - 0.0055 16.0 0.1 0.014 14.7 0.1 1.7 1 0 0 1 1 1 1 Zeta toxin DUF2209 PF09974.9 KFM24685.1 - 0.0099 16.2 0.2 0.021 15.1 0.2 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2209) SRPRB PF09439.10 KFM24685.1 - 0.016 14.6 0.4 2.5 7.5 0.0 2.5 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit AAA_19 PF13245.6 KFM24685.1 - 0.034 14.5 0.0 0.076 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 KFM24685.1 - 0.036 13.0 0.0 0.077 12.0 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA PF00004.29 KFM24685.1 - 0.04 14.3 0.1 0.46 10.9 0.1 2.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 KFM24685.1 - 0.046 13.7 2.0 0.26 11.3 2.0 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit CbiA PF01656.23 KFM24685.1 - 0.051 13.6 0.0 0.11 12.5 0.0 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATP_bind_1 PF03029.17 KFM24685.1 - 0.059 13.1 0.1 0.18 11.6 0.1 1.9 2 0 0 2 2 1 0 Conserved hypothetical ATP binding protein APS_kinase PF01583.20 KFM24685.1 - 0.064 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase 6PF2K PF01591.18 KFM24685.1 - 0.097 12.0 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 6-phosphofructo-2-kinase DUF373 PF04123.13 KFM24685.1 - 0.16 11.4 0.3 0.27 10.7 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) YlbD_coat PF14071.6 KFM24685.1 - 0.97 9.7 3.6 14 5.9 0.6 3.0 2 1 0 2 2 2 0 Putative coat protein Mito_carr PF00153.27 KFM24686.1 - 5.4e-47 157.7 1.0 1.7e-17 63.1 0.1 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein DUF3007 PF11460.8 KFM24688.1 - 4e-32 110.3 0.3 5.7e-32 109.8 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3007) DUF973 PF06157.11 KFM24688.1 - 0.081 12.0 0.3 0.099 11.7 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF973) Pyr_redox_2 PF07992.14 KFM24688.1 - 0.087 12.0 0.0 0.087 12.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CRISPR_Cas2 PF09827.9 KFM24688.1 - 0.17 12.1 0.2 4.9 7.4 0.0 2.2 2 0 0 2 2 2 0 CRISPR associated protein Cas2 JAB PF01398.21 KFM24689.1 - 2.2e-32 111.5 0.0 4e-32 110.7 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KFM24689.1 - 1.8e-09 38.0 0.4 3.3e-09 37.1 0.4 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 KFM24689.1 - 1.1e-05 25.1 0.0 1.9e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain FtsL PF04999.13 KFM24689.1 - 0.014 15.4 1.1 0.027 14.5 0.8 1.6 1 1 0 1 1 1 0 Cell division protein FtsL PseudoU_synth_2 PF00849.22 KFM24690.1 - 1.4e-17 64.3 0.0 4.2e-17 62.7 0.0 1.7 1 1 0 1 1 1 1 RNA pseudouridylate synthase ProRS-C_1 PF09180.11 KFM24691.1 - 5.6e-26 90.5 0.2 1.2e-25 89.5 0.2 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 KFM24691.1 - 2.3e-19 70.1 0.0 3.7e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KFM24691.1 - 1.1e-17 63.9 0.0 1.9e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain SNAPc19 PF15497.6 KFM24693.1 - 0.00011 22.6 1.4 0.00013 22.3 1.4 1.1 1 0 0 1 1 1 1 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Spc24 PF08286.11 KFM24693.1 - 0.13 12.5 1.8 0.16 12.2 1.3 1.4 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Abhydrolase_6 PF12697.7 KFM24694.1 - 1.6e-19 71.4 7.7 1.6e-19 71.4 7.7 2.9 2 2 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFM24694.1 - 2.6e-15 56.3 0.1 1.8e-14 53.6 0.1 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFM24694.1 - 1.7e-13 50.9 0.3 4e-13 49.6 0.3 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold DNA_photolyase PF00875.18 KFM24694.1 - 1.1e-12 48.3 0.0 2.2e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 DNA photolyase DUF1576 PF07613.11 KFM24694.1 - 0.036 13.6 0.3 0.084 12.4 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1576) Ndr PF03096.14 KFM24694.1 - 0.063 12.0 0.0 0.093 11.4 0.0 1.2 1 0 0 1 1 1 0 Ndr family HEAT PF02985.22 KFM24695.1 - 0.00029 20.8 0.0 6 7.4 0.0 5.5 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.7 KFM24695.1 - 0.00077 19.5 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Pkinase PF00069.25 KFM24695.1 - 0.001 18.5 0.0 0.0026 17.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain ANAPC4_WD40 PF12894.7 KFM24698.1 - 1.5e-12 47.6 0.0 0.0033 17.7 0.0 6.9 4 2 4 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFM24698.1 - 7.4e-09 36.1 5.5 0.55 11.2 0.0 8.2 10 0 0 10 10 10 3 WD domain, G-beta repeat PQQ_2 PF13360.6 KFM24698.1 - 0.061 12.9 5.1 0.69 9.4 2.1 3.3 2 2 2 4 4 4 0 PQQ-like domain Ldh_1_C PF02866.18 KFM24699.1 - 2.5e-46 157.7 0.0 3.9e-46 157.0 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KFM24699.1 - 6.4e-34 117.1 0.2 9.2e-34 116.5 0.2 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KFM24699.1 - 0.00052 19.1 0.0 0.00073 18.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 KFM24699.1 - 0.02 15.0 0.0 0.047 13.8 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 KFM24699.1 - 0.024 15.1 0.1 0.053 14.0 0.1 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 KFM24699.1 - 0.029 13.7 1.4 0.47 9.8 1.4 2.5 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Na_sulph_symp PF00939.19 KFM24700.1 - 1.2e-130 436.8 31.3 1.3e-130 436.6 31.3 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 KFM24700.1 - 4e-13 49.2 38.2 8.2e-13 48.2 38.0 1.6 1 1 0 1 1 1 1 Citrate transporter DuoxA PF10204.9 KFM24700.1 - 0.0099 14.9 1.5 0.0099 14.9 1.5 2.5 2 0 0 2 2 2 1 Dual oxidase maturation factor Solute_trans_a PF03619.16 KFM24701.1 - 1.1e-83 280.9 14.5 1.3e-83 280.6 14.5 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Ribosomal_L1 PF00687.21 KFM24703.1 - 1.9e-49 168.2 0.0 2.4e-49 167.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF383 PF04063.14 KFM24704.1 - 1.3e-20 73.8 0.0 9e-20 71.1 0.0 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF383) HEAT_2 PF13646.6 KFM24704.1 - 0.7 10.3 4.7 2 8.9 1.0 3.2 2 1 0 2 2 2 0 HEAT repeats HEAT_EZ PF13513.6 KFM24704.1 - 5.1 7.7 9.0 8.8 7.0 0.0 4.3 3 2 3 6 6 6 0 HEAT-like repeat GLTSCR1 PF15249.6 KFM24705.1 - 4.2e-11 43.2 0.0 6.4e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Conserved region of unknown function on GLTSCR protein Myb_DNA-bind_6 PF13921.6 KFM24706.1 - 1.8e-06 28.1 0.2 3.7e-06 27.1 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KFM24706.1 - 0.00015 21.9 0.2 0.0003 20.9 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 KFM24706.1 - 0.0025 17.8 0.2 0.094 12.8 0.1 2.6 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 KFM24706.1 - 0.15 12.3 0.1 0.28 11.4 0.1 1.4 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Phe_tRNA-synt_N PF02912.18 KFM24706.1 - 0.25 11.3 1.4 0.31 11.0 0.1 1.9 2 0 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain DUF3591 PF12157.8 KFM24708.1 - 3.8e-63 213.7 0.0 4.1e-49 167.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3591) Bromodomain PF00439.25 KFM24708.1 - 1.2e-09 38.1 0.0 2.1e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Bromodomain TBP-binding PF09247.11 KFM24708.1 - 2.6e-07 30.8 1.6 4.8e-07 29.9 1.6 1.4 1 0 0 1 1 1 1 TATA box-binding protein binding zf-CW PF07496.15 KFM24708.1 - 0.002 18.1 3.5 0.0034 17.4 3.5 1.4 1 0 0 1 1 1 1 CW-type Zinc Finger Cpn60_TCP1 PF00118.24 KFM24709.1 - 2.2e-14 53.0 0.0 2.4e-14 52.8 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cpn60_TCP1 PF00118.24 KFM24710.1 - 6.5e-99 331.8 14.2 1.3e-98 330.8 14.2 1.5 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF4355 PF14265.6 KFM24710.1 - 0.69 10.2 4.2 1.4 9.2 4.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) LPMO_10 PF03067.15 KFM24713.1 - 9.7e-17 62.3 0.1 1.3e-16 61.9 0.1 1.3 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading CBM_14 PF01607.24 KFM24713.1 - 1.9e-11 44.0 2.7 1.9e-11 44.0 2.7 2.7 2 1 0 2 2 2 1 Chitin binding Peritrophin-A domain HSP20 PF00011.21 KFM24713.1 - 0.035 14.2 0.0 0.051 13.7 0.0 1.2 1 0 0 1 1 1 0 Hsp20/alpha crystallin family He_PIG PF05345.12 KFM24713.1 - 0.057 13.6 3.6 0.72 10.1 1.8 2.6 2 0 0 2 2 2 0 Putative Ig domain Mnd1 PF03962.15 KFM24714.1 - 6.7e-26 90.4 0.2 1.3e-25 89.5 0.2 1.5 1 0 0 1 1 1 1 Mnd1 HTH domain LZ3wCH PF18517.1 KFM24714.1 - 6.3e-07 29.4 0.1 1.2e-06 28.5 0.1 1.4 1 0 0 1 1 1 1 Leucine zipper with capping helix domain GAS PF13851.6 KFM24714.1 - 0.059 12.7 3.1 0.086 12.2 3.1 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Seryl_tRNA_N PF02403.22 KFM24714.1 - 0.077 13.2 1.8 0.16 12.2 1.8 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain OmpH PF03938.14 KFM24714.1 - 0.086 13.2 2.9 0.15 12.4 2.9 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF373 PF04123.13 KFM24714.1 - 6.1 6.2 9.9 6.1 6.2 9.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF373) Lectin_N PF03954.14 KFM24714.1 - 6.5 6.5 7.0 0.9 9.3 1.1 2.3 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain ABC_tran_CTD PF16326.5 KFM24714.1 - 8.5 6.7 8.4 37 4.6 7.6 2.1 1 1 0 1 1 1 0 ABC transporter C-terminal domain DUF2009 PF09418.10 KFM24716.1 - 1e-204 680.8 0.0 1.3e-204 680.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) Hist_deacetyl PF00850.19 KFM24717.1 - 2.1e-77 260.6 0.0 2.6e-77 260.3 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain SURF1 PF02104.15 KFM24718.1 - 1.3e-36 126.5 0.1 1.5e-36 126.2 0.1 1.1 1 0 0 1 1 1 1 SURF1 family Tim17 PF02466.19 KFM24719.1 - 3.4e-16 59.6 5.0 4.9e-16 59.1 5.0 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Bacteriocin_IIc PF10439.9 KFM24719.1 - 0.02 15.0 15.0 0.27 11.4 2.7 2.8 3 0 0 3 3 3 0 Bacteriocin class II with double-glycine leader peptide Romo1 PF10247.9 KFM24719.1 - 0.97 9.9 13.2 0.14 12.6 0.9 3.2 1 1 2 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 Gly-zipper_Omp PF13488.6 KFM24719.1 - 2 8.5 17.2 0.4 10.7 1.8 2.6 2 0 0 2 2 2 0 Glycine zipper DUF5129 PF17173.4 KFM24720.1 - 0.024 13.8 0.8 0.03 13.4 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5129) CorA PF01544.18 KFM24720.1 - 0.12 11.6 0.9 0.23 10.7 0.9 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein PPR_2 PF13041.6 KFM24721.1 - 1.1e-11 44.7 0.0 1e-07 32.0 0.0 4.0 3 0 0 3 3 3 1 PPR repeat family PPR_3 PF13812.6 KFM24721.1 - 5.9e-10 39.1 0.0 2.3e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 Pentatricopeptide repeat domain PPR PF01535.20 KFM24721.1 - 1e-08 34.8 0.0 0.029 14.6 0.0 5.9 6 0 0 6 6 6 2 PPR repeat PPR_1 PF12854.7 KFM24721.1 - 2.7e-07 30.1 0.4 0.5 10.1 0.0 4.8 5 0 0 5 5 5 3 PPR repeat PPR_long PF17177.4 KFM24721.1 - 0.017 14.5 0.0 0.048 13.0 0.0 1.8 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP Cupin_4 PF08007.12 KFM24722.1 - 1.7e-38 132.9 0.0 2.6e-38 132.3 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 KFM24722.1 - 0.00053 19.8 0.0 0.1 12.3 0.0 2.2 1 1 0 1 1 1 1 Cupin-like domain AraC_binding PF02311.19 KFM24722.1 - 0.0064 16.4 0.0 0.039 13.9 0.0 2.4 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_2 PF07883.11 KFM24722.1 - 0.04 13.6 0.0 0.74 9.6 0.0 2.4 2 0 0 2 2 2 0 Cupin domain DUF4423 PF14394.6 KFM24722.1 - 0.27 10.9 0.0 0.45 10.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) WD40 PF00400.32 KFM24723.1 - 5.8e-09 36.4 2.6 1.4e-05 25.7 0.2 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM24723.1 - 1.9e-07 31.3 0.1 0.00059 20.1 0.0 3.9 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KFM24723.1 - 5.3e-06 26.2 0.0 1.3e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 PQQ-like domain PQQ_3 PF13570.6 KFM24723.1 - 1.5 9.4 11.3 3.6 8.2 0.7 4.4 4 1 0 4 4 4 0 PQQ-like domain SAP PF02037.27 KFM24724.1 - 1e-05 25.2 1.8 1e-05 25.2 1.8 1.8 2 0 0 2 2 2 1 SAP domain DUF1749 PF08538.10 KFM24725.1 - 3.3e-49 167.6 0.0 4.1e-49 167.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 KFM24725.1 - 0.00011 22.9 4.2 0.00014 22.6 4.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFM24725.1 - 0.0013 18.1 0.0 0.043 13.1 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF1057 PF06342.12 KFM24725.1 - 0.23 10.5 0.0 0.32 10.0 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Suf PF05843.14 KFM24726.1 - 3.5e-08 33.8 5.1 0.00054 20.0 0.1 3.8 2 1 2 4 4 4 2 Suppressor of forked protein (Suf) TPR_19 PF14559.6 KFM24726.1 - 2e-07 31.4 0.3 0.0041 17.6 0.0 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFM24726.1 - 9.8e-06 26.0 5.2 1.1 10.2 0.2 4.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFM24726.1 - 0.0002 21.8 2.2 0.76 10.5 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat PknG_TPR PF16918.5 KFM24726.1 - 0.00043 19.1 0.1 0.00077 18.3 0.1 1.4 1 0 0 1 1 1 1 Protein kinase G tetratricopeptide repeat TPR_8 PF13181.6 KFM24726.1 - 0.017 15.3 0.0 10 6.6 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFM24726.1 - 0.029 15.0 4.7 0.97 10.1 0.0 3.8 4 1 0 4 4 4 0 Tetratricopeptide repeat PSI_PsaF PF02507.15 KFM24727.1 - 1e-67 227.3 0.0 1.4e-67 226.8 0.0 1.2 1 0 0 1 1 1 1 Photosystem I reaction centre subunit III Unstab_antitox PF09720.10 KFM24727.1 - 0.14 12.2 0.2 2.9 8.0 0.0 2.7 2 1 1 3 3 3 0 Putative addiction module component AAA PF00004.29 KFM24729.1 - 1.1e-09 38.9 0.0 1.9e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KFM24729.1 - 0.00024 20.9 0.0 0.00052 19.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 KFM24729.1 - 0.0012 18.4 0.4 0.011 15.3 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 KFM24729.1 - 0.0018 18.6 0.0 0.013 15.9 0.0 2.3 2 0 0 2 2 2 1 AAA C-terminal domain AAA_18 PF13238.6 KFM24729.1 - 0.0056 17.2 0.0 0.11 13.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KFM24729.1 - 0.0071 16.1 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 KFM24729.1 - 0.0078 16.1 0.3 0.091 12.7 0.0 2.5 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_30 PF13604.6 KFM24729.1 - 0.011 15.4 0.1 0.034 13.9 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFM24729.1 - 0.013 15.9 0.5 0.073 13.4 0.1 2.5 2 1 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.14 KFM24729.1 - 0.016 15.2 0.0 0.043 13.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KFM24729.1 - 0.018 15.3 0.0 0.69 10.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KFM24729.1 - 0.051 13.6 0.0 0.088 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KFM24729.1 - 0.072 12.4 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NTPase_1 PF03266.15 KFM24729.1 - 0.29 11.0 0.0 1 9.2 0.0 1.8 2 0 0 2 2 2 0 NTPase Adap_comp_sub PF00928.21 KFM24730.1 - 1e-47 162.8 0.0 1.3e-47 162.4 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family muHD PF10291.9 KFM24730.1 - 0.00054 19.5 0.0 0.0093 15.4 0.0 2.4 3 0 0 3 3 3 1 Muniscin C-terminal mu homology domain DUF5462 PF17547.2 KFM24730.1 - 0.16 11.3 0.0 5.3 6.4 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5462) MOZ_SAS PF01853.18 KFM24731.1 - 4.6e-81 270.7 0.0 6.7e-81 270.2 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KFM24731.1 - 1.3e-21 75.9 1.3 1.3e-21 75.9 1.3 2.0 2 0 0 2 2 2 1 MYST family zinc finger domain Tudor-knot PF11717.8 KFM24731.1 - 1.3e-17 63.5 0.0 2.7e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 KFM24731.1 - 0.00041 20.7 0.0 0.00093 19.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Agenet PF05641.12 KFM24731.1 - 0.0009 19.7 0.2 0.0035 17.8 0.0 2.0 2 0 0 2 2 2 1 Agenet domain Chromo PF00385.24 KFM24731.1 - 0.0053 16.6 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain HTH_IclR PF09339.10 KFM24731.1 - 0.032 14.0 0.1 0.081 12.7 0.1 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain Cullin PF00888.22 KFM24731.1 - 0.11 11.1 0.0 0.17 10.4 0.0 1.3 1 0 0 1 1 1 0 Cullin family UAA PF08449.11 KFM24732.1 - 1.2e-57 195.4 3.2 1.3e-57 195.3 3.2 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KFM24732.1 - 1.5e-08 34.9 7.6 9.9e-07 29.0 2.7 2.3 2 0 0 2 2 2 2 EamA-like transporter family eIF-4B PF06273.11 KFM24733.1 - 0.0014 17.8 0.8 0.0014 17.8 0.8 2.3 1 1 1 2 2 2 1 Plant specific eukaryotic initiation factor 4B Serinc PF03348.15 KFM24734.1 - 1.4e-95 320.8 7.9 1.7e-95 320.5 7.9 1.1 1 0 0 1 1 1 1 Serine incorporator (Serinc) Chloroa_b-bind PF00504.21 KFM24735.1 - 4.7e-41 141.0 0.0 7.6e-41 140.3 0.0 1.3 1 0 0 1 1 1 1 Chlorophyll A-B binding protein RRM_1 PF00076.22 KFM24736.1 - 4.6e-41 138.5 0.1 5.9e-14 51.6 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFM24736.1 - 4.1e-13 49.3 0.1 1.6e-05 25.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif Nup35_RRM_2 PF14605.6 KFM24736.1 - 3.3e-08 33.4 0.1 0.019 15.0 0.0 3.3 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 KFM24736.1 - 0.011 16.0 0.1 10 6.3 0.0 2.8 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Ribosomal_L12 PF00542.19 KFM24737.1 - 8.8e-26 90.1 12.8 4.8e-25 87.7 11.3 2.1 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 KFM24737.1 - 1.1e-09 37.8 0.4 1.1e-09 37.8 0.4 3.4 4 0 0 4 4 4 1 Ribosomal protein L7/L12 dimerisation domain DEC-1_N PF04625.13 KFM24737.1 - 1.2 8.1 7.4 0.074 12.1 2.2 1.6 1 1 1 2 2 2 0 DEC-1 protein, N-terminal region FHA PF00498.26 KFM24738.1 - 8.5e-17 61.3 0.0 1.2e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KFM24738.1 - 4.2e-13 49.4 0.0 5.6e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain PRODH PF18327.1 KFM24738.1 - 0.019 15.2 2.1 0.034 14.4 2.1 1.4 1 0 0 1 1 1 0 Proline utilization A proline dehydrogenase N-terminal domain FHA_2 PF17913.1 KFM24738.1 - 0.029 14.6 0.0 0.038 14.2 0.0 1.2 1 0 0 1 1 1 0 FHA domain Haspin_kinase PF12330.8 KFM24739.1 - 4.2e-45 154.3 0.0 5.8e-45 153.8 0.0 1.0 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KFM24739.1 - 0.04 13.8 0.1 0.04 13.8 0.1 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 KFM24739.1 - 0.21 10.9 0.0 15 4.9 0.1 2.1 2 0 0 2 2 2 0 Protein kinase domain UEV PF05743.13 KFM24740.1 - 1.5e-17 63.5 0.2 2.4e-17 62.9 0.2 1.3 1 0 0 1 1 1 1 UEV domain Ribosomal_L7Ae PF01248.26 KFM24740.1 - 9.9e-15 54.1 0.0 1.5e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Vps23_core PF09454.10 KFM24740.1 - 7.7e-07 29.0 0.0 3.8e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 Vps23 core domain Ribosomal_S25 PF03297.15 KFM24741.1 - 1.5e-43 147.1 7.2 1.7e-43 146.9 7.2 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.6 KFM24741.1 - 0.019 14.5 0.2 0.03 13.9 0.2 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 KFM24741.1 - 0.079 12.9 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 MarR family RWP-RK PF02042.15 KFM24743.1 - 2.1e-21 75.6 0.1 3.1e-21 75.1 0.1 1.3 1 0 0 1 1 1 1 RWP-RK domain XhlA PF10779.9 KFM24743.1 - 0.032 14.4 0.1 0.055 13.7 0.1 1.3 1 0 0 1 1 1 0 Haemolysin XhlA Myosin_tail_1 PF01576.19 KFM24743.1 - 0.074 10.9 0.1 0.093 10.5 0.1 1.0 1 0 0 1 1 1 0 Myosin tail ERM PF00769.19 KFM24743.1 - 0.11 12.3 1.1 0.15 11.9 1.1 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF444 PF04285.12 KFM24743.1 - 0.13 11.3 0.1 0.15 11.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF444) MerR-DNA-bind PF09278.11 KFM24743.1 - 1.6 9.4 4.9 7.7 7.1 0.9 2.4 1 1 1 2 2 2 0 MerR, DNA binding LisH PF08513.11 KFM24744.1 - 0.0061 16.5 0.0 0.021 14.8 0.0 2.0 2 0 0 2 2 2 1 LisH ATG16 PF08614.11 KFM24744.1 - 0.0073 16.6 0.5 0.016 15.4 0.5 1.5 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DHR10 PF18595.1 KFM24744.1 - 0.082 13.0 4.1 0.18 11.8 4.1 1.5 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain CCDC144C PF14915.6 KFM24744.1 - 0.31 10.1 0.8 0.47 9.5 0.8 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region HEAT PF02985.22 KFM24744.1 - 6.3 7.4 21.5 0.71 10.3 0.8 6.4 4 1 1 5 5 5 0 HEAT repeat Ribosomal_S3_C PF00189.20 KFM24745.1 - 1.6e-24 86.2 3.3 5.4e-24 84.5 0.6 2.6 2 1 1 3 3 3 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 KFM24745.1 - 1e-10 41.3 0.3 1.7e-10 40.5 0.3 1.4 1 0 0 1 1 1 1 KH domain RRM_1 PF00076.22 KFM24747.1 - 5.9e-24 83.7 0.1 2.8e-12 46.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFM24747.1 - 3.3e-12 46.1 0.0 6.8e-05 22.5 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFM24747.1 - 0.01 15.7 0.0 0.54 10.1 0.0 2.2 2 0 0 2 2 2 0 Occluded RNA-recognition motif Gas_vesicle PF00741.18 KFM24747.1 - 0.19 11.9 0.2 0.34 11.1 0.2 1.3 1 0 0 1 1 1 0 Gas vesicle protein PX PF00787.24 KFM24748.1 - 1.4e-10 41.1 0.0 2.3e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 PX domain Fez1 PF06818.15 KFM24748.1 - 0.088 13.3 9.5 0.41 11.1 2.1 2.5 1 1 1 2 2 2 0 Fez1 CENP-F_leu_zip PF10473.9 KFM24748.1 - 1.4 8.9 9.7 0.57 10.2 1.9 2.9 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MIP-T3_C PF17749.1 KFM24748.1 - 2.7 8.0 8.8 1.9 8.5 2.2 2.6 1 1 1 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region Spc7 PF08317.11 KFM24748.1 - 8 5.2 11.4 21 3.9 11.3 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF373 PF04123.13 KFM24749.1 - 0.55 9.6 8.2 0.68 9.3 8.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF996 PF06195.13 KFM24749.1 - 1.9 8.8 11.3 3.2 8.0 11.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF996) Ac76 PF05814.11 KFM24749.1 - 7 6.7 7.6 0.57 10.2 1.5 2.2 1 1 1 2 2 2 0 Orf76 (Ac76) SMN PF06003.12 KFM24751.1 - 7e-05 22.2 3.4 0.0081 15.4 4.8 2.9 2 1 0 2 2 2 1 Survival motor neuron protein (SMN) DUF4537 PF15057.6 KFM24751.1 - 0.0059 16.6 0.7 0.0099 15.9 0.7 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4537) TAF4 PF05236.14 KFM24751.1 - 0.032 14.0 1.0 0.038 13.7 1.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Agenet PF05641.12 KFM24751.1 - 0.079 13.4 0.1 0.2 12.1 0.1 1.7 1 0 0 1 1 1 0 Agenet domain Sugar_tr PF00083.24 KFM24751.1 - 6.1 5.6 6.2 0.33 9.8 1.0 1.5 2 0 0 2 2 2 0 Sugar (and other) transporter Adaptin_N PF01602.20 KFM24752.1 - 2.5e-144 481.7 0.0 3.1e-144 481.4 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KFM24752.1 - 4.7e-64 215.3 0.1 8.6e-63 211.2 0.0 2.3 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KFM24752.1 - 6.4e-16 58.5 18.3 1.2e-05 25.6 0.0 6.4 4 1 2 6 6 6 4 HEAT repeats B2-adapt-app_C PF09066.10 KFM24752.1 - 4.5e-11 42.8 0.0 8.9e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT PF02985.22 KFM24752.1 - 7.8e-09 35.1 6.8 0.0016 18.5 0.1 5.2 6 0 0 6 6 5 3 HEAT repeat Cnd3 PF12719.7 KFM24752.1 - 1.3e-07 31.1 0.0 4.4e-06 26.1 0.0 2.5 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain Arm PF00514.23 KFM24752.1 - 0.0012 18.8 2.7 15 5.8 0.0 5.4 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 KFM24752.1 - 0.0057 16.8 0.1 1.3 9.3 0.0 4.0 2 2 1 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF4232 PF14016.6 KFM24752.1 - 0.017 15.3 0.8 0.046 13.9 0.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4232) HEAT_EZ PF13513.6 KFM24752.1 - 0.041 14.4 1.6 15 6.2 0.0 4.9 5 0 0 5 5 5 0 HEAT-like repeat UNC45-central PF11701.8 KFM24752.1 - 0.14 12.2 0.1 1.8 8.5 0.0 2.8 3 0 0 3 3 3 0 Myosin-binding striated muscle assembly central CLASP_N PF12348.8 KFM24752.1 - 0.21 11.1 0.0 4.4 6.8 0.0 2.7 2 1 1 3 3 3 0 CLASP N terminal IBN_N PF03810.19 KFM24753.1 - 0.031 14.2 0.0 0.097 12.6 0.0 1.9 1 0 0 1 1 1 0 Importin-beta N-terminal domain TPR_1 PF00515.28 KFM24755.1 - 1.5e-15 56.3 11.8 0.016 15.0 0.0 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat DnaJ PF00226.31 KFM24755.1 - 4.7e-13 49.1 0.1 1.2e-07 31.8 0.0 2.9 3 0 0 3 3 3 2 DnaJ domain TPR_2 PF07719.17 KFM24755.1 - 8e-11 41.2 24.0 0.027 14.5 0.2 7.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 KFM24755.1 - 2.5e-06 27.1 6.9 5.4 7.3 0.2 5.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFM24755.1 - 0.004 17.4 28.2 0.24 11.7 1.4 5.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFM24755.1 - 0.0064 17.1 16.9 0.0064 17.1 16.9 7.2 5 3 2 8 8 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFM24755.1 - 0.0085 16.6 24.9 0.035 14.6 0.0 6.0 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFM24755.1 - 0.018 15.4 0.8 33 5.2 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFM24755.1 - 0.032 14.1 0.8 0.032 14.1 0.8 5.9 6 1 1 7 7 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFM24755.1 - 0.18 12.7 0.1 0.18 12.7 0.1 8.0 7 2 2 9 9 7 0 Tetratricopeptide repeat DUF1896 PF08989.10 KFM24755.1 - 0.92 9.6 3.0 27 4.8 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1896) TPR_8 PF13181.6 KFM24755.1 - 1.1 9.7 4.3 39 4.8 0.1 4.7 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFM24755.1 - 2.3 9.1 14.4 9.9 7.1 0.0 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_21 PF09976.9 KFM24755.1 - 3.6 7.2 10.7 0.56 9.9 0.2 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat-like domain MFS_1 PF07690.16 KFM24756.1 - 5.6e-14 51.8 27.0 4.5e-09 35.7 14.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily ALG3 PF05208.13 KFM24757.1 - 6.7e-130 433.7 8.0 8.4e-130 433.3 8.0 1.1 1 0 0 1 1 1 1 ALG3 protein DXP_synthase_N PF13292.6 KFM24758.1 - 2.7e-112 374.4 0.7 1.9e-111 371.7 0.3 2.0 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.24 KFM24758.1 - 1.2e-42 145.6 0.3 2.6e-42 144.5 0.3 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KFM24758.1 - 2.7e-32 111.2 0.0 5.6e-32 110.2 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transketolase_N PF00456.21 KFM24758.1 - 2.7e-06 26.6 1.1 0.00027 20.0 1.1 2.9 2 1 0 3 3 3 1 Transketolase, thiamine diphosphate binding domain E1_dh PF00676.20 KFM24758.1 - 9.6e-06 24.7 0.2 1.7e-05 23.9 0.2 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KFM24758.1 - 2.1e-05 24.4 4.4 2.7e-05 24.0 0.9 2.7 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PFOR_II PF17147.4 KFM24758.1 - 0.11 12.8 0.0 0.32 11.3 0.0 1.8 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II UTP15_C PF09384.10 KFM24759.1 - 1.3e-30 106.0 0.0 1.9e-30 105.5 0.0 1.2 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 KFM24759.1 - 3.1e-20 72.1 10.7 0.0034 18.2 0.1 6.5 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM24759.1 - 2e-09 37.6 0.0 6.9e-05 23.1 0.0 4.1 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain FA_desaturase PF00487.24 KFM24760.1 - 1.9e-33 116.4 34.5 2.9e-33 115.8 34.5 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Aldose_epim PF01263.20 KFM24761.1 - 8.1e-44 150.1 0.0 9.1e-44 150.0 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase COX7C PF02935.16 KFM24762.1 - 1.6e-09 37.9 0.0 2.5e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc DNA_RNApol_7kD PF03604.13 KFM24763.1 - 0.0072 16.0 0.1 0.0072 16.0 0.1 1.8 2 0 0 2 2 2 1 DNA directed RNA polymerase, 7 kDa subunit Yippee-Mis18 PF03226.14 KFM24763.1 - 0.083 13.1 0.2 0.47 10.7 0.0 2.0 1 1 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly GFO_IDH_MocA PF01408.22 KFM24764.1 - 1.9e-08 35.2 0.0 3e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold SUKH-4 PF14435.6 KFM24764.1 - 0.018 15.1 0.4 0.024 14.7 0.4 1.4 1 1 0 1 1 1 0 SUKH-4 immunity protein Pentapeptide_2 PF01469.18 KFM24765.1 - 1.5e-09 37.6 15.0 1.5e-09 37.6 15.0 2.4 1 1 1 2 2 2 2 Pentapeptide repeats (8 copies) YecR PF13992.6 KFM24765.1 - 0.007 16.6 0.6 0.014 15.7 0.6 1.6 1 1 0 1 1 1 1 YecR-like lipoprotein PAXNEB PF05625.11 KFM24766.1 - 3.1e-12 46.3 0.0 9.3e-07 28.3 0.0 2.0 2 0 0 2 2 2 2 PAXNEB protein MFS_1 PF07690.16 KFM24767.1 - 6.7e-25 87.8 39.7 6.7e-25 87.8 39.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KFM24767.1 - 7.3e-17 60.8 19.2 1.9e-07 29.8 0.3 4.3 2 2 2 4 4 4 4 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 KFM24767.1 - 1.2e-06 27.7 20.6 2.5e-06 26.6 5.9 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 KFM24767.1 - 1.3e-05 24.6 11.3 1.3e-05 24.6 11.3 2.5 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB PseudoU_synth_2 PF00849.22 KFM24768.1 - 2.1e-16 60.4 0.0 9.2e-16 58.3 0.0 1.8 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 KFM24768.1 - 6.5e-06 25.8 0.0 1.2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 S4 domain CLP1_P PF16575.5 KFM24769.1 - 3.6e-63 212.8 0.0 4.9e-63 212.3 0.0 1.2 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 KFM24769.1 - 1.5e-25 89.9 0.0 2.6e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 ABC_tran PF00005.27 KFM24769.1 - 0.0033 17.9 0.0 0.0073 16.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 KFM24769.1 - 0.016 14.9 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFM24769.1 - 0.016 15.1 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 KFM24769.1 - 0.02 14.9 0.0 0.1 12.7 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_23 PF13476.6 KFM24769.1 - 0.046 14.2 0.1 0.078 13.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 KFM24769.1 - 0.056 13.2 0.0 0.089 12.6 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 KFM24769.1 - 0.1 12.1 0.0 0.47 10.0 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_21 PF13304.6 KFM24769.1 - 0.16 11.8 0.0 0.21 11.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Glyco_hydro_16 PF00722.21 KFM24770.1 - 9.9e-22 77.3 1.0 3.2e-21 75.6 1.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 KFM24770.1 - 2.1e-13 49.6 3.9 4.6e-06 25.3 0.0 2.1 1 1 1 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Glutenin_hmw PF03157.13 KFM24770.1 - 0.069 11.6 3.0 0.089 11.2 3.0 1.1 1 0 0 1 1 1 0 High molecular weight glutenin subunit CRAL_TRIO PF00650.20 KFM24771.1 - 7.5e-06 25.7 0.0 0.00013 21.8 0.0 2.3 2 1 1 3 3 3 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFM24771.1 - 8.8e-06 25.8 0.2 2.8e-05 24.2 0.1 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain bZIP_1 PF00170.21 KFM24772.1 - 3.2e-08 33.5 10.9 5.8e-08 32.7 10.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFM24772.1 - 3.9e-05 23.6 12.4 3.9e-05 23.6 12.4 1.8 2 0 0 2 2 2 1 Basic region leucine zipper YabA PF06156.13 KFM24772.1 - 0.0023 18.5 0.5 0.004 17.8 0.2 1.6 2 0 0 2 2 2 1 Initiation control protein YabA DUF5094 PF17015.5 KFM24772.1 - 0.029 14.5 0.1 0.039 14.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) CDC37_N PF03234.14 KFM24772.1 - 0.11 13.4 1.0 0.22 12.4 1.0 1.5 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding SelR PF01641.18 KFM24774.1 - 6e-39 132.9 0.0 8.9e-39 132.3 0.0 1.2 1 0 0 1 1 1 1 SelR domain NTP_transferase PF00483.23 KFM24775.1 - 7.1e-64 215.8 0.0 9.3e-64 215.4 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase polyprenyl_synt PF00348.17 KFM24775.1 - 9.6e-08 31.4 0.0 2.1e-07 30.3 0.0 1.6 2 0 0 2 2 2 1 Polyprenyl synthetase NTP_transf_3 PF12804.7 KFM24775.1 - 3.9e-05 24.1 0.0 6.8e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 KFM24775.1 - 0.06 12.3 0.0 0.31 9.9 0.0 2.0 2 0 0 2 2 2 0 L-fucokinase ATP-synt_DE_N PF02823.16 KFM24776.1 - 1.9e-14 53.3 0.0 2.9e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Get5_bdg PF16843.5 KFM24776.1 - 0.00084 18.8 0.3 0.0015 18.0 0.3 1.4 1 0 0 1 1 1 1 Binding domain to Get4 on Get5, Golgi to ER traffic protein Sel1 PF08238.12 KFM24777.1 - 1.7e-19 69.8 42.0 4.2e-06 27.2 2.2 8.3 9 0 0 9 9 9 6 Sel1 repeat Galactosyl_T PF01762.21 KFM24778.1 - 7.6e-40 136.8 0.0 9.7e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 KFM24778.1 - 0.0002 20.9 0.1 0.00038 20.0 0.1 1.5 1 1 0 1 1 1 1 Fringe-like Pkinase PF00069.25 KFM24779.1 - 3.4e-32 111.9 0.0 3e-19 69.4 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFM24779.1 - 2.2e-19 69.7 0.0 9.2e-09 35.0 0.1 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KFM24779.1 - 0.036 13.4 0.0 0.054 12.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like TraB PF01963.17 KFM24781.1 - 4.9e-15 56.1 0.0 7.3e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 TraB family ODC_AZ PF02100.17 KFM24781.1 - 0.14 12.2 0.4 1.1 9.2 0.0 2.3 3 0 0 3 3 3 0 Ornithine decarboxylase antizyme TPR_19 PF14559.6 KFM24782.1 - 9.9e-10 38.8 13.8 0.0044 17.5 0.2 5.9 3 1 3 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM24782.1 - 1.1e-07 32.0 4.1 0.0032 17.7 0.0 4.3 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KFM24782.1 - 4.8e-06 26.4 0.1 0.91 9.9 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFM24782.1 - 8e-06 26.1 35.1 0.14 12.4 5.8 7.4 7 2 0 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 KFM24782.1 - 1.6e-05 25.2 19.5 0.0051 17.4 0.0 7.8 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFM24782.1 - 5.7e-05 22.9 8.5 3.9 7.7 0.0 6.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFM24782.1 - 8e-05 22.5 15.8 3.8 7.9 0.1 7.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFM24782.1 - 0.00093 19.8 39.7 0.17 12.6 0.1 6.7 4 2 3 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFM24782.1 - 0.0022 17.7 3.7 4.7 7.2 0.1 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFM24782.1 - 0.037 14.2 18.6 0.27 11.4 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat SLT_L PF14718.6 KFM24782.1 - 0.096 12.8 0.8 9 6.5 0.0 3.4 3 0 0 3 3 3 0 Soluble lytic murein transglycosylase L domain TPR_20 PF14561.6 KFM24782.1 - 1.7 9.0 12.4 2 8.8 0.1 4.0 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFM24782.1 - 4.3 8.4 0.0 4.3 8.4 0.0 8.2 7 3 3 10 10 9 0 Tetratricopeptide repeat RHH_8 PF17723.1 KFM24783.1 - 0.14 12.3 0.1 0.29 11.3 0.1 1.5 1 0 0 1 1 1 0 Ribbon-Helix-Helix transcriptional regulator family AAA_5 PF07728.14 KFM24785.1 - 6.4e-125 411.7 0.0 3.2e-24 85.5 0.0 8.3 8 0 0 8 8 8 8 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 KFM24785.1 - 2.9e-40 136.7 0.0 2.4e-13 50.2 0.0 5.2 5 0 0 5 5 4 4 Midasin AAA lid domain AAA_3 PF07726.11 KFM24785.1 - 2.1e-33 115.0 0.0 8e-11 41.9 0.0 7.2 7 0 0 7 7 7 4 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFM24785.1 - 4.4e-29 102.1 16.1 2.9e-05 24.5 0.7 7.7 6 1 0 6 6 6 6 AAA ATPase domain AAA PF00004.29 KFM24785.1 - 1.4e-27 96.7 0.0 4.7e-05 23.8 0.0 6.5 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KFM24785.1 - 1.2e-25 90.1 0.0 1.4e-05 24.7 0.0 6.4 6 0 0 6 6 6 5 P-loop containing dynein motor region AAA_22 PF13401.6 KFM24785.1 - 1.6e-22 80.2 3.0 0.0012 19.1 0.0 7.1 6 1 0 6 6 6 5 AAA domain AAA_6 PF12774.7 KFM24785.1 - 5.2e-21 75.0 0.2 0.016 14.2 0.0 7.7 7 2 0 7 7 7 5 Hydrolytic ATP binding site of dynein motor region Dynein_heavy PF03028.15 KFM24785.1 - 1.4e-20 73.5 0.0 0.0052 16.9 0.0 7.0 7 0 0 7 7 6 4 Dynein heavy chain region D6 P-loop domain AAA_lid_5 PF17865.1 KFM24785.1 - 4e-20 71.9 0.0 1.6e-19 69.9 0.0 2.1 2 0 0 2 2 1 1 Midasin AAA lid domain AAA_18 PF13238.6 KFM24785.1 - 3.4e-19 69.7 0.6 0.01 16.4 0.0 6.5 6 0 0 6 6 6 4 AAA domain AAA_30 PF13604.6 KFM24785.1 - 1.3e-17 64.2 9.4 0.0058 16.4 0.0 7.0 7 0 0 7 7 6 5 AAA domain AAA_33 PF13671.6 KFM24785.1 - 6.7e-17 62.0 3.2 0.0058 16.8 0.0 6.8 6 0 0 6 6 6 3 AAA domain ABC_tran PF00005.27 KFM24785.1 - 1.5e-16 61.1 0.8 0.0048 17.4 0.0 6.3 6 0 0 6 6 6 3 ABC transporter TsaE PF02367.17 KFM24785.1 - 3e-15 56.3 9.2 0.018 15.1 0.2 6.4 6 0 0 6 6 6 3 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 KFM24785.1 - 6.8e-14 51.9 0.2 0.11 12.2 0.1 7.0 7 0 0 7 7 7 3 Sigma-54 interaction domain AAA_29 PF13555.6 KFM24785.1 - 9.2e-14 50.9 0.8 0.26 11.1 0.0 6.5 6 0 0 6 6 6 2 P-loop containing region of AAA domain Mg_chelatase PF01078.21 KFM24785.1 - 3e-13 49.6 13.1 0.0067 15.8 0.1 9.3 10 0 0 10 10 9 2 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 KFM24785.1 - 1.7e-12 47.6 0.1 0.26 11.2 0.0 6.1 6 0 0 6 6 6 3 RsgA GTPase NACHT PF05729.12 KFM24785.1 - 2.8e-12 46.8 9.6 0.043 13.7 0.1 6.4 6 0 0 6 6 6 4 NACHT domain AAA_14 PF13173.6 KFM24785.1 - 1.8e-11 44.2 0.0 0.17 11.9 0.0 6.3 7 0 0 7 7 6 2 AAA domain AAA_25 PF13481.6 KFM24785.1 - 2.6e-11 43.5 11.5 0.28 10.7 0.0 6.6 6 0 0 6 6 6 3 AAA domain RNA_helicase PF00910.22 KFM24785.1 - 3.8e-11 43.3 0.2 0.99 9.8 0.0 6.2 6 0 0 6 6 6 2 RNA helicase T2SSE PF00437.20 KFM24785.1 - 3.8e-11 42.6 1.4 0.017 14.2 0.0 6.2 6 0 0 6 6 6 1 Type II/IV secretion system protein Zeta_toxin PF06414.12 KFM24785.1 - 4.1e-11 42.5 6.1 0.014 14.7 0.0 6.1 6 0 0 6 6 6 2 Zeta toxin Sigma54_activ_2 PF14532.6 KFM24785.1 - 8.6e-11 42.1 0.1 0.0065 16.6 0.0 5.8 6 0 0 6 6 5 2 Sigma-54 interaction domain AAA_28 PF13521.6 KFM24785.1 - 1.2e-10 41.9 13.2 0.49 10.6 0.1 6.6 6 0 0 6 6 6 3 AAA domain AAA_24 PF13479.6 KFM24785.1 - 6e-10 39.2 0.1 3 7.5 0.0 5.6 6 0 0 6 6 5 0 AAA domain IstB_IS21 PF01695.17 KFM24785.1 - 7.2e-10 38.9 1.7 0.085 12.6 0.0 6.2 6 0 0 6 6 6 1 IstB-like ATP binding protein RuvB_N PF05496.12 KFM24785.1 - 1.8e-09 37.5 5.4 0.68 9.7 0.1 7.2 7 0 0 7 7 7 1 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 KFM24785.1 - 2.3e-09 37.7 8.6 0.43 10.9 0.2 6.4 6 0 0 6 6 5 1 AAA domain DUF815 PF05673.13 KFM24785.1 - 2.5e-08 33.4 2.5 0.2 10.8 0.0 5.7 6 0 0 6 6 6 2 Protein of unknown function (DUF815) PduV-EutP PF10662.9 KFM24785.1 - 3.7e-07 30.0 5.1 0.26 11.1 0.1 5.9 6 0 0 6 6 6 2 Ethanolamine utilisation - propanediol utilisation MCM PF00493.23 KFM24785.1 - 5.7e-07 28.9 0.0 0.72 8.9 0.0 4.9 5 0 0 5 5 5 2 MCM P-loop domain Rad17 PF03215.15 KFM24785.1 - 6.4e-07 29.5 0.4 11 5.9 0.0 5.6 6 0 0 6 6 6 0 Rad17 P-loop domain AAA_23 PF13476.6 KFM24785.1 - 1.7e-06 28.7 0.7 7.4 7.0 0.0 5.8 6 0 0 6 6 6 0 AAA domain Viral_helicase1 PF01443.18 KFM24785.1 - 2.3e-06 27.5 0.0 4.2 7.0 0.0 5.2 6 0 0 6 6 5 0 Viral (Superfamily 1) RNA helicase MMR_HSR1 PF01926.23 KFM24785.1 - 2.6e-06 27.5 2.1 13 5.9 0.0 5.6 6 0 0 6 6 5 0 50S ribosome-binding GTPase AAA_8 PF12780.7 KFM24785.1 - 2.7e-06 26.9 0.7 0.47 9.7 0.0 5.3 6 0 0 6 6 5 1 P-loop containing dynein motor region D4 cobW PF02492.19 KFM24785.1 - 2.7e-06 27.1 11.7 0.83 9.2 0.1 5.4 6 0 0 6 6 5 2 CobW/HypB/UreG, nucleotide-binding domain AAA_11 PF13086.6 KFM24785.1 - 2.8e-06 27.3 0.0 5.8 6.6 0.0 5.8 6 0 0 6 6 6 0 AAA domain AAA_2 PF07724.14 KFM24785.1 - 7e-06 26.3 0.0 4.7 7.3 0.0 5.6 6 0 0 6 6 5 0 AAA domain (Cdc48 subfamily) Roc PF08477.13 KFM24785.1 - 7.9e-06 26.1 5.6 0.72 10.1 0.0 5.9 6 0 0 6 6 6 1 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 KFM24785.1 - 8.9e-06 25.5 8.2 1.6 8.3 0.2 5.5 6 0 0 6 6 5 1 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.17 KFM24785.1 - 1e-05 25.5 5.8 4.5 7.0 0.0 5.7 6 0 0 6 6 6 0 Conserved hypothetical ATP binding protein dNK PF01712.19 KFM24785.1 - 1.2e-05 25.3 1.2 14 5.4 0.0 5.1 5 0 0 5 5 5 0 Deoxynucleoside kinase TniB PF05621.11 KFM24785.1 - 6.3e-05 22.5 0.0 4.1 6.8 0.0 5.2 6 0 0 6 6 6 0 Bacterial TniB protein CPT PF07931.12 KFM24785.1 - 0.00013 21.8 3.9 9 6.1 0.0 5.6 4 1 0 4 4 4 0 Chloramphenicol phosphotransferase-like protein CbiA PF01656.23 KFM24785.1 - 0.00031 20.8 0.0 3.4 7.7 0.0 4.1 4 1 0 4 4 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATPase_2 PF01637.18 KFM24785.1 - 0.00037 20.5 0.0 9.7 6.0 0.0 4.5 4 0 0 4 4 4 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 KFM24785.1 - 0.00038 20.4 8.2 9.2 6.1 0.0 5.6 6 0 0 6 6 5 0 NTPase ATPase PF06745.13 KFM24785.1 - 0.0011 18.3 3.0 3.4 6.9 0.0 4.3 5 0 0 5 5 4 0 KaiC AAA_21 PF13304.6 KFM24785.1 - 0.0013 18.6 1.0 6.4 6.5 0.0 4.6 5 0 0 5 5 4 0 AAA domain, putative AbiEii toxin, Type IV TA system DAP3 PF10236.9 KFM24785.1 - 0.0014 17.8 2.0 3.3 6.8 0.0 3.5 4 0 0 4 4 3 0 Mitochondrial ribosomal death-associated protein 3 ResIII PF04851.15 KFM24785.1 - 0.0036 17.3 1.6 7.3 6.6 0.1 4.1 5 0 0 5 5 3 0 Type III restriction enzyme, res subunit AAA_17 PF13207.6 KFM24785.1 - 0.0044 17.4 4.6 5.8 7.3 0.0 5.0 5 0 0 5 5 5 0 AAA domain SRPRB PF09439.10 KFM24785.1 - 0.0078 15.7 4.7 11 5.4 0.1 5.2 6 0 0 6 6 5 0 Signal recognition particle receptor beta subunit FtsK_SpoIIIE PF01580.18 KFM24785.1 - 0.011 15.1 1.6 8.5 5.6 0.0 4.4 5 0 0 5 5 5 0 FtsK/SpoIIIE family NB-ARC PF00931.22 KFM24785.1 - 0.013 14.7 4.1 8.5 5.5 0.1 4.6 5 0 0 5 5 5 0 NB-ARC domain DUF927 PF06048.11 KFM24785.1 - 0.015 14.9 0.0 3.7 7.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF927) Ploopntkinase3 PF18751.1 KFM24785.1 - 0.02 14.8 2.4 22 4.9 0.0 4.4 5 0 0 5 5 4 0 P-loop Nucleotide Kinase3 TIP49 PF06068.13 KFM24785.1 - 0.034 13.4 8.5 0.31 10.2 0.0 4.6 5 0 0 5 5 5 0 TIP49 P-loop domain Gliadin PF13016.6 KFM24785.1 - 0.076 13.4 0.3 0.66 10.4 0.5 2.2 2 0 0 2 2 2 0 Cys-rich Gliadin N-terminal Bac_DnaA PF00308.18 KFM24785.1 - 0.15 11.9 0.2 3.8 7.3 0.0 3.0 4 0 0 4 4 2 0 Bacterial dnaA protein KAP_NTPase PF07693.14 KFM24785.1 - 0.15 11.2 0.0 17 4.5 0.0 2.7 3 0 0 3 3 2 0 KAP family P-loop domain MeaB PF03308.16 KFM24785.1 - 0.19 10.6 3.6 26 3.7 0.2 3.5 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB IPT PF01745.16 KFM24785.1 - 0.2 11.1 4.3 3.3 7.0 0.0 3.6 5 0 0 5 5 3 0 Isopentenyl transferase PhoH PF02562.16 KFM24785.1 - 0.22 10.9 8.0 19 4.6 0.2 4.5 5 0 0 5 5 4 0 PhoH-like protein G-alpha PF00503.20 KFM24785.1 - 0.44 9.7 1.2 19 4.3 0.0 2.9 4 0 0 4 4 2 0 G-protein alpha subunit FeoB_N PF02421.18 KFM24785.1 - 0.44 10.1 1.2 69 2.9 0.0 3.7 4 0 0 4 4 3 0 Ferrous iron transport protein B Septin PF00735.18 KFM24785.1 - 0.49 9.6 5.2 3.5 6.8 0.0 3.1 5 0 0 5 5 2 0 Septin Adeno_IVa2 PF02456.15 KFM24785.1 - 0.51 9.1 0.8 19 3.9 0.0 3.0 3 0 0 3 3 3 0 Adenovirus IVa2 protein Cytidylate_kin PF02224.18 KFM24785.1 - 0.62 9.7 8.0 44 3.7 0.0 4.8 6 0 0 6 6 4 0 Cytidylate kinase TrwB_AAD_bind PF10412.9 KFM24785.1 - 0.69 8.7 4.4 21 3.9 0.2 4.1 5 0 0 5 5 4 0 Type IV secretion-system coupling protein DNA-binding domain Ras PF00071.22 KFM24785.1 - 1.3 8.6 2.3 28 4.3 0.0 3.4 4 0 0 4 4 3 0 Ras family DUF2075 PF09848.9 KFM24785.1 - 8.1 5.6 6.5 1.6e+02 1.3 0.1 4.2 5 0 0 5 5 5 0 Uncharacterized conserved protein (DUF2075) MobB PF03205.14 KFM24785.1 - 9.3 6.2 7.6 9.3 6.1 0.1 4.1 6 0 0 6 6 3 0 Molybdopterin guanine dinucleotide synthesis protein B NatB_MDM20 PF09797.9 KFM24786.1 - 5.2e-15 55.3 0.0 5.6e-14 51.9 0.0 2.0 1 1 1 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit USP7_C2 PF14533.6 KFM24786.1 - 1.5e-09 37.9 0.0 2.3e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal TPR_19 PF14559.6 KFM24786.1 - 0.54 10.8 18.8 0.099 13.2 0.8 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF2514 PF10721.9 KFM24787.1 - 0.5 10.4 8.4 0.07 13.2 2.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) DAO PF01266.24 KFM24788.1 - 1.1e-18 68.0 0.0 1.3e-18 67.8 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase 5-FTHF_cyc-lig PF01812.20 KFM24790.1 - 5.6e-32 111.1 0.1 1.6e-31 109.6 0.1 1.6 1 1 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family DUF3248 PF11609.8 KFM24790.1 - 0.015 15.2 0.1 0.053 13.5 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3248) Me-amine-dh_L PF02975.14 KFM24792.1 - 0.063 13.8 0.1 0.13 12.8 0.1 1.5 1 0 0 1 1 1 0 Methylamine dehydrogenase, L chain DUF2116 PF09889.9 KFM24792.1 - 1 9.4 2.9 0.6 10.1 0.6 1.8 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Peptidase_M76 PF09768.9 KFM24793.1 - 1.6e-41 142.0 3.2 1.6e-41 142.0 3.2 1.6 2 0 0 2 2 2 1 Peptidase M76 family ArfGap PF01412.18 KFM24793.1 - 1.9e-32 111.8 0.1 1.9e-32 111.8 0.1 1.6 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf MORN PF02493.20 KFM24793.1 - 2.2e-14 52.4 7.4 6.1e-05 22.7 0.4 4.3 4 0 0 4 4 4 3 MORN repeat BSP PF04450.12 KFM24793.1 - 0.2 11.4 0.1 0.32 10.7 0.1 1.2 1 0 0 1 1 1 0 Peptidase of plants and bacteria Galactosyl_T PF01762.21 KFM24794.1 - 4.6e-09 36.4 0.0 8.2e-09 35.6 0.0 1.4 1 1 0 1 1 1 1 Galactosyltransferase PD40 PF07676.12 KFM24794.1 - 6.5e-05 22.7 0.2 0.00014 21.7 0.2 1.6 1 0 0 1 1 1 1 WD40-like Beta Propeller Repeat eIF-3c_N PF05470.12 KFM24795.1 - 5.1e-138 461.0 3.6 6.7e-82 275.7 0.0 3.9 1 1 3 4 4 4 3 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 KFM24795.1 - 3.2e-12 46.9 0.0 1.2e-11 45.1 0.0 2.0 2 0 0 2 2 2 1 PCI domain CDC45 PF02724.14 KFM24795.1 - 0.17 10.1 5.9 0.25 9.6 5.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Tmemb_cc2 PF10267.9 KFM24795.1 - 0.82 8.7 4.7 1.3 8.1 4.7 1.4 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Apt1 PF10351.9 KFM24795.1 - 1.2 8.0 9.0 1.6 7.5 9.0 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Hid1 PF12722.7 KFM24795.1 - 2.7 6.0 4.4 3.8 5.5 4.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Macoilin PF09726.9 KFM24795.1 - 2.8 6.4 7.2 4.1 5.8 7.2 1.1 1 0 0 1 1 1 0 Macoilin family DNA_pol_phi PF04931.13 KFM24795.1 - 6.6 4.7 9.6 10 4.1 9.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi WD40 PF00400.32 KFM24796.1 - 1e-08 35.7 9.1 6.7e-05 23.6 0.4 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat F-box-like PF12937.7 KFM24796.1 - 7.7e-08 32.1 4.6 7.7e-08 32.1 4.6 2.1 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KFM24796.1 - 3.4e-06 26.8 1.8 9e-06 25.4 1.8 1.6 1 0 0 1 1 1 1 F-box domain F-box_5 PF18511.1 KFM24796.1 - 0.039 13.5 0.5 0.21 11.2 0.3 2.1 2 0 0 2 2 2 0 F-box PQQ_3 PF13570.6 KFM24796.1 - 0.043 14.3 12.7 0.099 13.2 0.0 5.5 7 0 0 7 7 7 0 PQQ-like domain PQQ PF01011.21 KFM24796.1 - 1.7 8.7 3.8 24 5.1 0.1 3.7 4 0 0 4 4 4 0 PQQ enzyme repeat Ion_trans PF00520.31 KFM24797.1 - 6.1e-13 48.6 18.5 8.9e-13 48.0 18.5 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KFM24797.1 - 6.5e-09 35.6 14.7 2.1e-08 34.0 14.1 2.2 1 1 1 2 2 2 1 Ion channel UPF0182 PF03699.13 KFM24797.1 - 3.7 5.6 7.3 5.5 5.0 7.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) HGTP_anticodon PF03129.20 KFM24798.1 - 6.6e-14 51.8 0.0 1.2e-13 51.0 0.0 1.4 1 1 0 1 1 1 1 Anticodon binding domain SecY PF00344.20 KFM24799.1 - 1.6e-12 47.3 0.0 2.7e-11 43.3 0.0 2.0 1 1 0 1 1 1 1 SecY translocase SecY PF00344.20 KFM24801.1 - 0.0061 15.8 0.2 0.0079 15.5 0.2 1.1 1 0 0 1 1 1 1 SecY translocase SPT2 PF08243.11 KFM24802.1 - 0.0058 17.1 1.1 0.0067 16.9 1.1 1.1 1 0 0 1 1 1 1 SPT2 chromatin protein bZIP_1 PF00170.21 KFM24802.1 - 0.015 15.4 7.4 0.025 14.7 7.4 1.3 1 0 0 1 1 1 0 bZIP transcription factor SRP-alpha_N PF04086.13 KFM24802.1 - 0.18 11.7 2.0 0.2 11.6 2.0 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal bZIP_2 PF07716.15 KFM24802.1 - 0.37 10.9 11.2 0.54 10.4 11.2 1.3 1 0 0 1 1 1 0 Basic region leucine zipper H2TH PF06831.14 KFM24803.1 - 1.8e-24 85.5 0.0 3.3e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Fapy_DNA_glyco PF01149.24 KFM24803.1 - 2e-07 31.6 0.0 3.4e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain SAP PF02037.27 KFM24803.1 - 1.9e-06 27.5 0.0 3.5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 SAP domain FbpA PF05833.11 KFM24803.1 - 0.0098 14.7 0.0 0.013 14.3 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) La PF05383.17 KFM24804.1 - 1.4e-22 79.5 0.0 2.2e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 KFM24804.1 - 0.086 12.7 0.0 0.42 10.5 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MMtag PF10159.9 KFM24805.1 - 4.6e-28 97.3 5.1 4.6e-28 97.3 5.1 1.5 2 0 0 2 2 2 1 Multiple myeloma tumor-associated DNA_pol_B_thumb PF14791.6 KFM24805.1 - 0.065 13.4 0.9 0.26 11.5 0.6 2.2 2 1 0 2 2 2 0 DNA polymerase beta thumb Hydrolase_4 PF12146.8 KFM24806.1 - 9e-13 48.0 0.0 4.9e-12 45.6 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFM24806.1 - 1.5e-09 37.9 0.2 1.5e-08 34.6 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFM24806.1 - 4e-08 34.1 16.9 4e-08 34.1 16.9 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.20 KFM24806.1 - 0.00035 20.8 0.1 0.00057 20.1 0.1 1.3 1 0 0 1 1 1 1 Thioesterase domain BAAT_C PF08840.11 KFM24806.1 - 0.012 15.6 0.1 0.052 13.5 0.1 1.9 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal GNT-I PF03071.15 KFM24807.1 - 4.9e-106 355.1 0.0 6.6e-106 354.7 0.0 1.0 1 0 0 1 1 1 1 GNT-I family Glycos_transf_2 PF00535.26 KFM24807.1 - 0.00097 19.0 0.1 0.0029 17.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KFM24807.1 - 0.0016 18.4 0.0 0.0044 16.9 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Acetyltransf_1 PF00583.25 KFM24809.1 - 1.3e-13 51.2 0.0 1.8e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFM24809.1 - 1.2e-10 41.4 0.0 1.8e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFM24809.1 - 1.7e-08 34.8 0.0 4.3e-08 33.5 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KFM24809.1 - 2.8e-05 24.2 0.0 4.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFM24809.1 - 0.00073 19.5 0.0 0.0037 17.2 0.0 2.1 2 0 0 2 2 2 1 FR47-like protein Choline_kinase PF01633.20 KFM24810.1 - 6.3e-43 146.8 0.0 9.2e-43 146.3 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KFM24810.1 - 1.1e-13 51.7 1.5 5.4e-13 49.4 1.5 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Rep_fac-A_C PF08646.10 KFM24811.1 - 4.6e-34 117.3 0.0 7.8e-34 116.5 0.0 1.4 1 0 0 1 1 1 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 KFM24811.1 - 7.4e-24 83.5 0.3 1.3e-19 69.9 0.0 3.4 3 1 0 3 3 3 2 Replication protein A OB domain tRNA_anti-codon PF01336.25 KFM24811.1 - 1.4e-05 24.9 0.4 0.0012 18.8 0.0 3.2 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain Rep-A_N PF04057.12 KFM24811.1 - 3.6e-05 23.7 0.0 0.0001 22.3 0.0 1.8 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain TIG_plexin PF17960.1 KFM24811.1 - 0.04 13.9 0.0 0.095 12.7 0.0 1.6 1 0 0 1 1 1 0 TIG domain DUF223 PF02721.14 KFM24811.1 - 0.2 11.9 0.0 0.41 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF223 Nucleotid_trans PF03407.16 KFM24812.1 - 2.8e-44 151.6 0.0 3.6e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase RBD PF02196.15 KFM24813.1 - 0.058 13.5 0.2 12 6.0 0.1 2.4 2 0 0 2 2 2 0 Raf-like Ras-binding domain DUF1850 PF08905.11 KFM24813.1 - 0.13 12.6 0.0 4.6 7.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1850) DUF3851 PF12962.7 KFM24813.1 - 1.1 9.5 5.6 5.3 7.4 0.6 2.6 2 2 0 2 2 2 0 Protein of unknown function (DUF3851) Nucleotid_trans PF03407.16 KFM24814.1 - 3e-38 131.9 0.0 3.7e-38 131.6 0.0 1.1 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Sir1 PF11603.8 KFM24814.1 - 0.12 12.9 0.1 0.22 12.0 0.1 1.3 1 0 0 1 1 1 0 Regulatory protein Sir1 Nucleotid_trans PF03407.16 KFM24815.1 - 2.2e-38 132.4 0.0 3.1e-38 131.9 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Nucleotid_trans PF03407.16 KFM24816.1 - 2.8e-33 115.7 0.0 4.2e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase RRM_1 PF00076.22 KFM24817.1 - 9.1e-40 134.3 0.0 8e-17 60.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFM24817.1 - 5.7e-07 29.6 0.7 0.043 13.9 0.1 3.5 2 1 1 3 3 3 3 RNA recognition motif MFS_1 PF07690.16 KFM24818.1 - 6.2e-34 117.5 24.1 9.6e-34 116.8 24.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM24818.1 - 9.8e-08 31.3 22.3 3.1e-07 29.6 7.7 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 KFM24818.1 - 0.028 13.3 13.0 0.2 10.5 0.1 3.0 2 1 1 3 3 3 0 MFS_1 like family DUF3483 PF11982.8 KFM24818.1 - 0.06 13.0 3.2 0.11 12.1 3.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3483) OATP PF03137.20 KFM24818.1 - 0.27 9.5 2.9 4.2 5.5 0.0 2.8 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Tcp11 PF05794.13 KFM24820.1 - 0.00015 21.0 0.0 0.019 14.1 0.0 2.0 1 1 1 2 2 2 2 T-complex protein 11 RIO1 PF01163.22 KFM24821.1 - 2e-50 171.0 0.0 2.6e-50 170.6 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 KFM24821.1 - 1.9e-14 53.6 0.4 5.3e-14 52.2 0.3 1.8 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.23 KFM24821.1 - 6.8e-11 42.6 1.6 1.9e-05 24.7 0.3 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KFM24821.1 - 6e-09 35.6 2.6 1.3e-07 31.2 0.3 2.7 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KFM24821.1 - 3e-05 23.5 0.4 0.00027 20.4 0.4 2.0 1 1 0 1 1 1 1 Protein kinase domain PIP49_C PF12260.8 KFM24821.1 - 0.0026 17.4 0.1 0.0041 16.8 0.1 1.3 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Choline_kinase PF01633.20 KFM24821.1 - 0.0027 17.3 0.1 0.0043 16.7 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.6 KFM24821.1 - 0.0035 16.7 0.0 0.0099 15.2 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pkinase_Tyr PF07714.17 KFM24821.1 - 0.024 13.9 0.0 0.037 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase WD40 PF00400.32 KFM24822.1 - 1.5e-58 193.3 28.3 9.5e-09 35.8 0.4 9.1 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM24822.1 - 1.2e-23 83.2 2.3 0.00051 20.3 0.1 5.5 3 2 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 KFM24822.1 - 1e-12 48.4 0.1 2e-12 47.5 0.1 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain Ge1_WD40 PF16529.5 KFM24822.1 - 2.6e-09 36.5 0.3 0.095 11.6 0.0 4.2 3 1 0 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KFM24822.1 - 1.2e-07 31.8 0.0 0.054 13.4 0.0 3.9 2 2 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KFM24822.1 - 0.0018 16.9 0.1 0.043 12.4 0.0 2.6 3 0 0 3 3 3 1 Cytochrome D1 heme domain WD40_like PF17005.5 KFM24822.1 - 0.03 13.7 0.0 32 3.7 0.0 3.3 4 0 0 4 4 4 0 WD40-like domain Nup160 PF11715.8 KFM24822.1 - 0.031 12.9 1.8 14 4.2 0.0 3.7 3 1 0 4 4 4 0 Nucleoporin Nup120/160 PD40 PF07676.12 KFM24822.1 - 0.048 13.6 0.7 29 4.8 0.1 4.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat FAD_binding_9 PF08021.11 KFM24822.1 - 0.093 12.9 0.0 0.35 11.1 0.0 1.9 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain Frtz PF11768.8 KFM24822.1 - 0.11 10.8 0.0 5.5 5.2 0.0 2.5 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Proteasome_A_N PF10584.9 KFM24822.1 - 0.5 10.1 3.2 5.8 6.7 0.0 3.6 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Glycos_transf_2 PF00535.26 KFM24823.1 - 4.5e-22 78.6 0.0 1.1e-21 77.4 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KFM24823.1 - 1.6e-07 31.5 0.0 2.2e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KFM24823.1 - 0.15 11.5 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 DCP1 PF06058.13 KFM24824.1 - 4.3e-35 120.2 0.0 5.7e-35 119.8 0.0 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family EVE PF01878.18 KFM24825.1 - 5.8e-29 101.0 0.0 3.6e-19 69.2 0.0 2.0 1 1 1 2 2 2 2 EVE domain Acylphosphatase PF00708.18 KFM24826.1 - 7.7e-21 74.3 0.1 8.1e-21 74.2 0.1 1.0 1 0 0 1 1 1 1 Acylphosphatase SNF2_N PF00176.23 KFM24827.1 - 2.6e-53 181.0 0.0 1e-24 86.9 0.0 3.6 3 1 0 3 3 3 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KFM24827.1 - 2.9e-12 46.9 0.0 6.1e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_4 PF15227.6 KFM24827.1 - 7.4e-10 38.8 7.1 2.4e-09 37.2 7.1 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KFM24827.1 - 2.3e-09 37.1 4.0 7.3e-09 35.5 4.0 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFM24827.1 - 2.2e-08 33.8 6.9 2.2e-08 33.8 6.9 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM24827.1 - 3.7e-07 30.0 6.8 3.7e-07 30.0 6.8 2.9 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFM24827.1 - 1.3e-06 28.2 4.8 1.3e-06 28.2 4.8 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM24827.1 - 4.4e-06 26.9 6.5 4.4e-06 26.9 6.5 3.0 3 1 0 3 3 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFM24827.1 - 5.8e-06 26.0 7.2 5.8e-06 26.0 7.2 2.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFM24827.1 - 0.00041 20.1 6.9 0.00041 20.1 6.9 2.1 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-C2HC_2 PF13913.6 KFM24827.1 - 0.0017 18.2 0.8 0.0062 16.4 0.1 2.4 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-rbx1 PF12678.7 KFM24827.1 - 0.0024 18.1 5.7 0.0089 16.3 5.7 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 KFM24827.1 - 0.0094 15.8 4.6 0.021 14.7 4.6 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein DUF3587 PF12132.8 KFM24827.1 - 2.9 7.3 5.9 6.3 6.2 5.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3587) zf-TFIIIC PF12660.7 KFM24827.1 - 5.2 7.1 6.2 3.5 7.6 1.6 2.6 3 0 0 3 3 2 0 Putative zinc-finger of transcription factor IIIC complex Thi4 PF01946.17 KFM24829.1 - 2.4e-141 468.8 2.1 4.8e-82 274.7 0.2 3.0 1 1 2 3 3 3 3 Thi4 family FAD_binding_2 PF00890.24 KFM24829.1 - 8.9e-07 28.3 0.2 0.00072 18.7 0.0 3.1 3 0 0 3 3 3 1 FAD binding domain DAO PF01266.24 KFM24829.1 - 1.3e-05 25.0 0.1 5.6e-05 22.9 0.0 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFM24829.1 - 0.00012 22.2 0.1 0.0008 19.6 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFM24829.1 - 0.00077 18.8 0.0 0.0015 17.8 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Antig_Caf1 PF09255.10 KFM24829.1 - 0.0018 18.4 0.0 2.9 8.0 0.0 2.3 2 0 0 2 2 2 2 Caf1 Capsule antigen FAD_binding_3 PF01494.19 KFM24829.1 - 0.0077 15.5 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KFM24829.1 - 0.02 13.9 0.0 0.043 12.9 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein B12D PF06522.11 KFM24829.1 - 0.02 14.6 0.0 0.047 13.5 0.0 1.6 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit HI0933_like PF03486.14 KFM24829.1 - 0.041 12.6 0.0 0.062 12.0 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 KFM24829.1 - 0.075 12.3 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KFM24829.1 - 0.089 11.9 0.0 0.21 10.6 0.0 1.6 1 0 0 1 1 1 0 Glucose inhibited division protein A DuffyBP_N PF12377.8 KFM24829.1 - 0.16 12.3 0.3 46 4.5 0.0 3.1 4 0 0 4 4 2 0 Duffy binding protein N terminal CDC45 PF02724.14 KFM24829.1 - 0.17 10.2 0.0 7.7 4.7 0.0 2.0 2 0 0 2 2 2 0 CDC45-like protein UQ_con PF00179.26 KFM24830.1 - 1.5e-39 134.9 0.0 1.8e-39 134.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFM24830.1 - 0.00089 19.0 0.0 0.0011 18.7 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KFM24830.1 - 0.0037 17.5 0.0 0.0045 17.3 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 KFM24830.1 - 0.0069 16.2 0.0 0.0095 15.8 0.0 1.1 1 0 0 1 1 1 1 UEV domain Prok-E2_A PF14457.6 KFM24830.1 - 0.14 11.8 0.1 0.17 11.5 0.1 1.1 1 0 0 1 1 1 0 Prokaryotic E2 family A ADK PF00406.22 KFM24831.1 - 1.6e-46 158.1 0.0 2e-46 157.8 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KFM24831.1 - 2e-23 83.3 0.0 3.9e-23 82.4 0.0 1.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KFM24831.1 - 0.00022 21.8 0.0 0.00034 21.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFM24831.1 - 0.0011 19.1 0.0 0.021 15.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KFM24831.1 - 0.013 15.2 0.0 7.3 6.2 0.0 2.9 2 1 1 3 3 3 0 Thymidylate kinase Hydin_ADK PF17213.3 KFM24831.1 - 0.15 12.3 0.1 0.23 11.7 0.1 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain ADK_lid PF05191.14 KFM24831.1 - 0.16 12.0 0.1 1.7 8.7 0.1 2.3 1 1 0 1 1 1 0 Adenylate kinase, active site lid Pentapeptide_2 PF01469.18 KFM24832.1 - 0.00051 19.9 31.4 0.00094 19.0 31.4 1.4 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_2 PF01469.18 KFM24833.1 - 0.00011 22.0 27.3 0.00011 22.0 27.3 2.0 1 1 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_2 PF01469.18 KFM24834.1 - 9.7e-06 25.4 26.9 9e-05 22.3 26.9 2.0 1 1 0 1 1 1 1 Pentapeptide repeats (8 copies) Galactosyl_T PF01762.21 KFM24835.1 - 1.2e-19 70.9 0.0 2.8e-19 69.7 0.0 1.6 1 1 0 1 1 1 1 Galactosyltransferase DUF2423 PF10338.9 KFM24837.1 - 8.9e-05 22.6 0.4 8.9e-05 22.6 0.4 3.8 2 1 1 4 4 4 1 Protein of unknown function (DUF2423) DUF5033 PF16436.5 KFM24837.1 - 0.1 12.5 0.3 0.14 12.1 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5033) DUF2390 PF09523.10 KFM24837.1 - 0.53 10.6 3.5 8.4 6.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2390) IF3_N PF05198.16 KFM24839.1 - 2.1e-18 66.4 0.3 4.8e-18 65.2 0.3 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain IF3_C PF00707.22 KFM24839.1 - 3.3e-07 30.2 0.0 6.1e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain 2_5_RNA_ligase2 PF13563.6 KFM24839.1 - 0.0049 16.8 1.3 0.022 14.6 1.3 2.2 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily Ribosomal_L12_N PF16320.5 KFM24839.1 - 0.044 13.5 0.2 0.18 11.5 0.2 2.1 1 0 0 1 1 1 0 Ribosomal protein L7/L12 dimerisation domain CHCH PF06747.13 KFM24839.1 - 0.39 10.9 1.7 0.7 10.1 1.7 1.4 1 0 0 1 1 1 0 CHCH domain LigT_PEase PF02834.16 KFM24839.1 - 0.81 9.9 6.0 15 5.8 0.1 3.6 4 0 0 4 4 4 0 LigT like Phosphoesterase MPC PF03650.13 KFM24840.1 - 2.1e-14 53.6 0.3 2.3e-14 53.5 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers E1-E2_ATPase PF00122.20 KFM24841.1 - 7.7e-33 113.5 0.0 3.5e-32 111.4 0.0 2.1 1 1 1 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KFM24841.1 - 5.9e-31 107.6 0.8 5.9e-31 107.6 0.8 1.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KFM24841.1 - 1.1e-16 61.8 0.6 3.7e-11 43.7 0.4 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFM24841.1 - 2.7e-13 49.8 0.0 5.7e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KFM24841.1 - 1.6e-10 40.5 0.2 1.6e-09 37.3 0.0 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KFM24841.1 - 1.8e-06 27.9 0.5 3.8e-06 26.8 0.5 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase CclA_1 PF16942.5 KFM24841.1 - 0.016 15.5 2.1 3 8.2 0.0 3.1 2 0 0 2 2 2 0 Putative cyclic bacteriocin Glu_synthase PF01645.17 KFM24841.1 - 1.5 7.9 6.8 0.47 9.5 1.9 2.3 2 0 0 2 2 2 0 Conserved region in glutamate synthase 2-oxoacid_dh PF00198.23 KFM24842.1 - 1.3e-71 240.8 0.0 2.3e-71 240.0 0.0 1.4 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KFM24842.1 - 1e-17 63.7 0.1 1.8e-17 62.9 0.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KFM24842.1 - 1.2e-14 54.3 1.6 1.9e-14 53.7 0.1 2.3 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 KFM24842.1 - 8.9e-05 22.2 0.0 0.0055 16.5 0.0 2.8 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 KFM24842.1 - 0.018 15.8 0.1 0.3 11.8 0.0 2.8 2 1 1 3 3 3 0 HlyD family secretion protein HlyD_D23 PF16576.5 KFM24842.1 - 0.06 12.6 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Sybindin PF04099.12 KFM24843.1 - 3.7e-33 114.4 0.0 4.2e-33 114.3 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Cupin_8 PF13621.6 KFM24844.1 - 2.6e-38 132.2 0.0 4.4e-38 131.4 0.0 1.3 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KFM24844.1 - 7.7e-10 38.7 0.0 1.2e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 KFM24844.1 - 0.0014 19.1 0.0 0.0042 17.5 0.0 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 KFM24844.1 - 0.14 11.9 0.0 0.36 10.6 0.0 1.7 1 0 0 1 1 1 0 Cupin domain SH3BGR PF04908.15 KFM24845.1 - 1.1e-06 28.8 0.0 1.1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 KFM24845.1 - 2.6e-06 27.6 0.0 4.1e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 KFM24845.1 - 0.072 13.5 0.0 0.11 13.0 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Pkinase PF00069.25 KFM24846.1 - 1.9e-64 217.5 0.0 1.2e-58 198.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Acyl-CoA_dh_1 PF00441.24 KFM24846.1 - 1.3e-25 90.3 0.5 1.3e-25 90.3 0.5 2.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Pkinase_Tyr PF07714.17 KFM24846.1 - 1.5e-22 80.1 0.0 4.7e-22 78.5 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase AidB_N PF18158.1 KFM24846.1 - 4.3e-22 78.7 0.0 1e-21 77.5 0.0 1.7 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_M PF02770.19 KFM24846.1 - 2.2e-12 47.0 0.0 4.1e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain LRR_8 PF13855.6 KFM24846.1 - 5.8e-11 42.0 10.4 9.8e-07 28.4 2.5 4.3 3 2 1 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 KFM24846.1 - 6.1e-11 42.4 1.6 0.00062 20.1 0.3 4.7 2 2 2 4 4 4 2 Leucine Rich repeats (2 copies) Acyl-CoA_dh_2 PF08028.11 KFM24846.1 - 2.8e-05 24.4 0.2 2.8e-05 24.4 0.2 3.2 4 0 0 4 4 3 1 Acyl-CoA dehydrogenase, C-terminal domain LRR_9 PF14580.6 KFM24846.1 - 0.12 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeat LRR_6 PF13516.6 KFM24846.1 - 0.12 12.5 3.6 48 4.4 0.2 5.1 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 KFM24846.1 - 0.29 11.8 8.1 1.5e+02 3.6 0.2 6.3 6 0 0 6 6 6 0 Leucine Rich Repeat Response_reg PF00072.24 KFM24848.1 - 6.7e-21 74.6 0.1 1.1e-20 73.8 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Myb_DNA-binding PF00249.31 KFM24848.1 - 0.0019 18.3 0.0 0.0032 17.6 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain KH_1 PF00013.29 KFM24850.1 - 4.2e-47 157.8 14.0 1.6e-15 56.7 0.6 3.3 3 0 0 3 3 3 3 KH domain MOEP19 PF16005.5 KFM24850.1 - 9.5e-13 48.0 0.0 0.0037 17.2 0.0 3.2 3 0 0 3 3 3 3 KH-like RNA-binding domain KH_4 PF13083.6 KFM24850.1 - 9.8e-12 44.6 5.1 0.0011 18.8 0.1 3.6 3 0 0 3 3 3 3 KH domain WW PF00397.26 KFM24850.1 - 9.7e-11 41.6 1.2 1.8e-10 40.7 1.2 1.4 1 0 0 1 1 1 1 WW domain KH_2 PF07650.17 KFM24850.1 - 4.3e-10 39.3 2.8 0.0036 17.1 0.8 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 KFM24850.1 - 0.0041 17.2 4.2 11 6.2 0.2 3.5 3 0 0 3 3 3 2 NusA-like KH domain DUF2786 PF10979.8 KFM24850.1 - 0.14 12.1 3.1 1.3 9.0 2.6 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2786) Peptidase_S41 PF03572.18 KFM24851.1 - 7.1e-43 146.1 0.0 1.2e-42 145.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S41 PDZ_6 PF17820.1 KFM24851.1 - 3.8e-13 49.1 1.0 1.4e-12 47.2 1.0 2.1 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFM24851.1 - 2.8e-06 27.6 0.0 5.4e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFM24851.1 - 2.2e-05 24.7 0.0 4.9e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Urb2 PF10441.9 KFM24851.1 - 8.9e-05 22.5 0.3 0.0012 18.9 0.0 3.0 2 2 0 2 2 2 1 Urb2/Npa2 family YbjQ_1 PF01906.17 KFM24853.1 - 0.026 15.2 0.1 0.057 14.1 0.1 1.5 1 0 0 1 1 1 0 Putative heavy-metal-binding DUF5360 PF17314.2 KFM24853.1 - 0.11 12.5 0.8 0.27 11.3 0.8 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5360) PQ-loop PF04193.14 KFM24854.1 - 3.3e-18 65.2 3.9 1.5e-09 37.5 0.0 2.9 4 0 0 4 4 4 2 PQ loop repeat MtN3_slv PF03083.16 KFM24854.1 - 0.049 13.7 1.2 0.11 12.5 0.0 2.1 3 0 0 3 3 3 0 Sugar efflux transporter for intercellular exchange ABC1 PF03109.16 KFM24855.1 - 3.4e-27 95.0 0.0 6.3e-27 94.1 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Indigoidine_A PF04227.12 KFM24856.1 - 2.5e-76 256.9 6.8 7.9e-55 186.3 0.0 2.0 1 1 1 2 2 2 2 Indigoidine synthase A like protein TBCC PF07986.12 KFM24857.1 - 3.5e-07 30.0 0.0 5.5e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 KFM24857.1 - 1.5e-06 28.6 1.9 0.0036 17.7 0.0 2.2 1 1 1 2 2 2 2 Tubulin-specific chaperone C N-terminal domain Ocular_alb PF02101.15 KFM24858.1 - 0.09 11.7 0.4 0.1 11.5 0.4 1.0 1 0 0 1 1 1 0 Ocular albinism type 1 protein SOCS PF12610.8 KFM24858.1 - 0.093 13.1 2.6 0.16 12.4 2.6 1.4 1 0 0 1 1 1 0 Suppressor of cytokine signalling GCIP PF13324.6 KFM24859.1 - 1.1e-19 71.1 0.0 1.6e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting GCIP PF13324.6 KFM24860.1 - 1.2e-12 48.1 0.0 1.7e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting DNA_pol_delta_4 PF04081.13 KFM24861.1 - 5.1e-22 78.6 0.0 5.8e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 DNA_pol_delta_4 PF04081.13 KFM24862.1 - 5.1e-22 78.6 0.0 5.8e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 TSP_1 PF00090.19 KFM24864.1 - 0.0074 16.5 6.0 0.0074 16.5 6.0 3.6 3 0 0 3 3 3 2 Thrombospondin type 1 domain Met_10 PF02475.16 KFM24864.1 - 0.069 12.9 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Mak10 PF04112.13 KFM24866.1 - 3.5e-23 81.9 0.7 1.9e-15 56.7 0.0 2.5 2 1 1 3 3 3 2 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Nucleoporin_FG2 PF15967.5 KFM24867.1 - 0.87 8.0 27.7 1 7.8 27.7 1.0 1 0 0 1 1 1 0 Nucleoporin FG repeated region DUF773 PF05600.12 KFM24868.1 - 1.5e-59 202.1 0.0 3.1e-52 178.0 0.0 2.0 1 1 0 2 2 2 2 CDK5 regulatory subunit-associated protein 3 HEAT_2 PF13646.6 KFM24869.1 - 1.7e-25 89.2 15.0 1.8e-12 47.5 0.1 3.1 2 1 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.16 KFM24869.1 - 4.8e-21 73.2 14.2 0.00013 22.3 0.0 5.4 5 0 0 5 5 5 5 PBS lyase HEAT-like repeat HEAT PF02985.22 KFM24869.1 - 8.7e-06 25.6 7.9 0.29 11.5 0.2 5.9 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 KFM24869.1 - 0.0024 18.4 9.7 6.4 7.4 0.0 4.9 5 1 0 5 5 5 3 HEAT-like repeat Exostosin PF03016.15 KFM24871.1 - 1e-43 149.7 0.4 1.8e-43 148.9 0.0 1.5 2 0 0 2 2 2 1 Exostosin family EGF_2 PF07974.13 KFM24871.1 - 2.7e-06 27.6 53.8 0.00074 19.8 8.9 4.4 4 0 0 4 4 4 3 EGF-like domain EGF PF00008.27 KFM24871.1 - 0.0026 18.0 5.3 0.0026 18.0 5.3 4.5 4 0 0 4 4 4 2 EGF-like domain hEGF PF12661.7 KFM24871.1 - 0.01 16.5 6.3 0.01 16.5 6.3 4.2 4 0 0 4 4 4 0 Human growth factor-like EGF GST_N_3 PF13417.6 KFM24872.1 - 1.6e-12 47.6 0.1 6e-12 45.8 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KFM24872.1 - 1.5e-07 31.6 0.0 3.6e-07 30.4 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFM24872.1 - 1.2e-06 28.4 0.2 3.6e-06 26.9 0.2 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KFM24872.1 - 6e-06 26.5 0.0 1.1e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 KFM24872.1 - 9.6e-05 22.9 0.0 0.00019 22.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFM24872.1 - 0.00079 19.6 0.0 0.0015 18.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KFM24872.1 - 0.16 12.7 0.0 0.35 11.6 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain LRR_4 PF12799.7 KFM24873.1 - 1.3e-19 69.9 14.8 5.3e-07 29.8 0.7 3.7 1 1 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFM24873.1 - 1.2e-17 63.9 0.1 5.8e-07 29.2 0.0 2.6 1 1 3 4 4 4 3 Leucine-rich repeat LRR_8 PF13855.6 KFM24873.1 - 2e-12 46.7 16.4 7.6e-07 28.8 4.7 4.3 2 1 2 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 KFM24873.1 - 0.00032 20.9 14.6 11 7.0 0.3 6.4 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_6 PF13516.6 KFM24873.1 - 0.0072 16.3 17.8 0.24 11.6 0.2 6.1 7 0 0 7 7 7 2 Leucine Rich repeat Skp1_POZ PF03931.15 KFM24874.1 - 7.7e-11 42.0 0.0 1.2e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.31 KFM24874.1 - 0.0014 18.8 0.1 0.0029 17.8 0.1 1.5 1 1 0 1 1 1 1 BTB/POZ domain Mito_carr PF00153.27 KFM24875.1 - 2.7e-43 145.8 3.7 2.7e-17 62.5 0.1 4.0 3 1 1 4 4 4 4 Mitochondrial carrier protein zf-HIT PF04438.16 KFM24876.1 - 1.6e-09 37.4 10.7 2.4e-09 36.9 10.7 1.3 1 0 0 1 1 1 1 HIT zinc finger PolC_DP2 PF03833.13 KFM24876.1 - 0.45 8.3 2.3 0.5 8.2 2.3 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-MYND PF01753.18 KFM24876.1 - 1.2 9.3 13.3 1.9 8.6 13.3 1.3 1 0 0 1 1 1 0 MYND finger PI3_PI4_kinase PF00454.27 KFM24877.1 - 0.0018 18.1 0.2 0.0063 16.4 0.2 1.7 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase APH PF01636.23 KFM24877.1 - 0.078 12.9 5.5 0.28 11.1 5.5 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF724 PF05266.14 KFM24878.1 - 1.2 8.9 0.0 1.2 8.9 0.0 4.4 5 1 1 6 6 6 0 Protein of unknown function (DUF724) LRR_6 PF13516.6 KFM24879.1 - 3.3e-09 36.1 4.4 0.016 15.2 0.1 5.7 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.7 KFM24879.1 - 0.0052 17.2 0.0 6.2 7.4 0.0 4.2 3 1 1 4 4 4 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM24879.1 - 0.13 12.9 0.6 3.2e+02 2.6 0.0 4.7 4 2 0 4 4 4 0 Leucine Rich Repeat Thioredoxin PF00085.20 KFM24880.1 - 3.2e-39 133.0 0.1 6e-18 64.7 0.1 3.5 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.6 KFM24880.1 - 4.1e-05 23.6 0.0 0.052 13.4 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 KFM24880.1 - 0.00023 21.6 0.0 1.2 9.6 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KFM24880.1 - 0.00038 20.6 0.0 0.0079 16.4 0.0 2.9 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_3 PF13192.6 KFM24880.1 - 0.098 12.7 0.1 0.4 10.8 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin domain Macoilin PF09726.9 KFM24880.1 - 0.15 10.6 5.8 0.23 10.0 5.8 1.1 1 0 0 1 1 1 0 Macoilin family Caa3_CtaG PF09678.10 KFM24882.1 - 0.095 12.1 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) TspO_MBR PF03073.15 KFM24883.1 - 1.5e-50 170.8 14.0 1.7e-50 170.6 14.0 1.0 1 0 0 1 1 1 1 TspO/MBR family TspO_MBR PF03073.15 KFM24884.1 - 5.7e-40 136.5 12.4 7.6e-40 136.1 12.4 1.1 1 0 0 1 1 1 1 TspO/MBR family SKG6 PF08693.10 KFM24884.1 - 0.21 11.0 0.2 0.21 11.0 0.2 1.6 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Histone_H2A_C PF16211.5 KFM24885.1 - 1.1e-19 69.9 1.3 1.9e-19 69.1 1.3 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KFM24885.1 - 4.7e-15 56.1 0.0 5.8e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFM24885.1 - 1.6e-05 25.1 0.0 2.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFM24886.1 - 7e-17 62.0 0.2 8.9e-17 61.7 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFM24886.1 - 0.0068 16.7 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RP-C PF03428.13 KFM24886.1 - 0.11 12.1 0.2 2.1 7.9 0.0 2.0 1 1 1 2 2 2 0 Replication protein C N-terminal domain Histone PF00125.24 KFM24887.1 - 7.6e-53 178.4 2.5 8.5e-53 178.2 2.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 KFM24887.1 - 0.0001 22.9 1.4 0.00013 22.6 1.4 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 KFM24887.1 - 0.00018 21.8 0.0 0.00027 21.2 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KFM24887.1 - 0.00026 21.0 0.7 0.00035 20.6 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KFM24887.1 - 0.0015 18.8 0.1 0.0029 17.9 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KFM24887.1 - 0.0096 16.0 0.2 0.018 15.1 0.0 1.5 2 0 0 2 2 2 1 Transcription initiation factor IID, 31kD subunit PRAI PF00697.22 KFM24887.1 - 0.17 11.6 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase CENP-T_C PF15511.6 KFM24888.1 - 2e-08 34.3 0.1 2.5e-08 34.0 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KFM24888.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KFM24888.1 - 0.00022 21.3 0.1 0.00031 20.8 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.13 KFM24888.1 - 0.0011 18.9 0.1 0.0017 18.4 0.1 1.2 1 0 0 1 1 1 1 Bromodomain associated CBFD_NFYB_HMF PF00808.23 KFM24888.1 - 0.0013 19.0 0.0 0.0022 18.3 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFM24888.1 - 0.0015 18.9 0.1 0.0017 18.8 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KFM24888.1 - 0.033 14.3 0.0 0.037 14.1 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Peptidase_M14 PF00246.24 KFM24889.1 - 9.8e-16 58.4 0.0 1.6e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase BRAP2 PF07576.12 KFM24890.1 - 1.5e-19 70.0 0.0 2.6e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 KFM24890.1 - 2e-18 66.5 6.0 2e-18 66.5 6.0 2.2 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 KFM24890.1 - 1.5e-09 38.0 6.9 1.5e-09 38.0 6.9 2.5 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFM24890.1 - 1e-07 31.6 4.7 1e-07 31.6 4.7 2.5 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFM24890.1 - 7.6e-06 26.1 4.4 7.6e-06 26.1 4.4 2.0 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KFM24890.1 - 1.3e-05 25.1 4.5 1.3e-05 25.1 4.5 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KFM24890.1 - 1.7e-05 24.6 7.2 1.7e-05 24.6 7.2 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFM24890.1 - 1.8e-05 24.4 1.3 1.8e-05 24.4 1.3 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KFM24890.1 - 0.00031 20.7 3.1 0.00031 20.7 3.1 2.8 1 1 1 2 2 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 KFM24890.1 - 0.0032 17.2 2.1 0.0032 17.2 2.1 2.3 1 1 1 2 2 1 1 RING/Ubox like zinc-binding domain Alanine_zipper PF11839.8 KFM24890.1 - 0.14 12.5 22.7 0.27 11.6 22.7 1.4 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein zf-ANAPC11 PF12861.7 KFM24890.1 - 0.17 12.0 8.2 0.043 13.9 4.9 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger TMCO5 PF14992.6 KFM24890.1 - 0.49 9.9 2.3 0.69 9.4 2.3 1.1 1 0 0 1 1 1 0 TMCO5 family LCD1 PF09798.9 KFM24890.1 - 1 7.8 1.8 1.5 7.3 1.8 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF2058 PF09831.9 KFM24890.1 - 4.1 7.5 9.2 5.9 7.0 9.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Prok-RING_4 PF14447.6 KFM24890.1 - 8.6 6.3 24.0 0.11 12.4 5.2 3.5 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 Pyr_redox_2 PF07992.14 KFM24893.1 - 6e-59 199.7 0.4 8e-59 199.3 0.4 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KFM24893.1 - 3.3e-33 114.2 0.2 6.3e-33 113.3 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KFM24893.1 - 1.7e-17 63.7 0.0 8.7e-17 61.5 0.0 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFM24893.1 - 4.8e-11 42.5 0.0 7.4e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFM24893.1 - 9.1e-05 21.7 0.1 0.0019 17.4 0.0 2.1 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) malic PF00390.19 KFM24893.1 - 0.1 12.4 0.1 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 Malic enzyme, N-terminal domain RNA_pol_A_bac PF01000.26 KFM24894.1 - 4.4e-26 91.4 0.0 1.6e-25 89.6 0.0 1.9 3 0 0 3 3 3 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KFM24894.1 - 1.3e-18 66.1 0.0 1.9e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF22 PF01629.16 KFM24894.1 - 0.13 11.9 0.1 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF22 DUF4187 PF13821.6 KFM24895.1 - 2.7e-18 65.5 0.3 5e-18 64.6 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 KFM24895.1 - 5e-10 39.1 0.3 8.1e-10 38.4 0.3 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KFM24895.1 - 0.00036 20.6 0.2 0.00062 19.8 0.2 1.4 1 0 0 1 1 1 1 G-patch domain Dicer_dimer PF03368.14 KFM24895.1 - 0.1 12.8 0.1 0.14 12.3 0.1 1.2 1 0 0 1 1 1 0 Dicer dimerisation domain SNARE_assoc PF09335.11 KFM24896.1 - 8.1e-15 55.4 2.8 1.3e-14 54.7 2.8 1.4 1 0 0 1 1 1 1 SNARE associated Golgi protein Pribosyltran PF00156.27 KFM24897.1 - 9.9e-18 64.2 0.0 1.6e-07 30.9 0.0 2.3 2 0 0 2 2 2 2 Phosphoribosyl transferase domain Pribosyltran_N PF13793.6 KFM24897.1 - 1e-13 51.2 0.0 2.7e-05 24.1 0.0 3.7 4 0 0 4 4 4 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KFM24897.1 - 7.6e-11 42.4 0.0 0.00048 20.2 0.0 2.2 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain UPRTase PF14681.6 KFM24897.1 - 0.039 13.4 0.0 4.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Uracil phosphoribosyltransferase Tet_res_leader PF08050.12 KFM24897.1 - 0.069 13.0 0.4 5.5 6.9 0.1 2.5 2 0 0 2 2 2 0 Tetracycline resistance leader peptide CRAL_TRIO PF00650.20 KFM24897.1 - 0.22 11.2 0.0 0.48 10.1 0.0 1.5 1 0 0 1 1 1 0 CRAL/TRIO domain Ceramidase PF05875.12 KFM24898.1 - 8.9e-05 22.0 0.6 0.041 13.3 0.1 2.3 2 0 0 2 2 2 2 Ceramidase DUF3522 PF12036.8 KFM24898.1 - 0.06 13.6 2.5 2.1 8.6 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3522) HlyIII PF03006.20 KFM24898.1 - 0.34 10.6 3.9 0.88 9.2 0.1 2.1 1 1 1 2 2 2 0 Haemolysin-III related Aa_trans PF01490.18 KFM24899.1 - 6.8e-73 245.7 7.8 7.6e-73 245.5 7.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KFM24899.1 - 0.0051 15.9 6.1 0.0051 15.9 6.1 2.2 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Ribosomal_S6 PF01250.17 KFM24900.1 - 1.7e-19 69.9 0.0 2.1e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 Fasciclin PF02469.22 KFM24901.1 - 1.7e-16 60.6 0.0 5.6e-16 58.9 0.0 1.7 1 1 0 1 1 1 1 Fasciclin domain DUF1995 PF09353.10 KFM24902.1 - 3.7e-34 118.5 0.0 4.4e-34 118.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) DHquinase_I PF01487.15 KFM24903.1 - 6.7e-42 144.3 0.0 1.3e-41 143.3 0.0 1.5 2 0 0 2 2 2 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.11 KFM24903.1 - 1.1e-22 80.1 0.0 2.2e-22 79.1 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 KFM24903.1 - 7.8e-08 32.0 0.4 2e-07 30.6 0.4 1.7 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KFM24903.1 - 1.2e-06 28.7 0.1 2.2e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KFM24903.1 - 0.00014 22.3 1.1 0.00033 21.2 1.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 KFM24903.1 - 0.00029 21.1 0.3 0.0013 19.0 0.5 2.1 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 KFM24903.1 - 0.00061 19.2 0.1 0.0012 18.3 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PALP PF00291.25 KFM24903.1 - 0.0034 16.8 1.6 0.0065 15.9 1.6 1.5 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme adh_short PF00106.25 KFM24903.1 - 0.0043 16.5 1.3 0.0073 15.8 1.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Pyr_redox_2 PF07992.14 KFM24903.1 - 0.017 14.3 1.5 0.034 13.4 1.5 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 KFM24903.1 - 0.03 13.7 0.6 0.53 9.6 1.5 2.1 1 1 1 2 2 2 0 ThiF family GIDA PF01134.22 KFM24903.1 - 0.034 13.2 2.9 0.049 12.7 2.9 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_2 PF03446.15 KFM24903.1 - 0.065 13.4 0.2 0.12 12.5 0.2 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KFM24903.1 - 0.11 12.1 0.1 0.11 12.1 0.1 1.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 KFM24903.1 - 0.11 11.7 2.6 0.24 10.6 2.6 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KFM24903.1 - 0.12 12.2 1.4 0.2 11.5 1.4 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Smr PF01713.21 KFM24906.1 - 1.4e-09 38.1 1.0 4.7e-08 33.3 0.9 2.4 2 1 0 2 2 2 1 Smr domain DUF1771 PF08590.10 KFM24906.1 - 4.4e-09 36.6 6.2 9.6e-09 35.5 6.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Lycopene_cycl PF05834.12 KFM24907.1 - 1e-117 393.5 0.0 1.2e-117 393.2 0.0 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KFM24907.1 - 1.1e-07 31.4 0.0 4.9e-05 22.7 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFM24907.1 - 1.8e-06 27.8 0.1 0.00046 19.9 0.1 2.4 1 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KFM24907.1 - 7.4e-06 25.4 0.3 0.0007 18.9 0.0 2.2 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 KFM24907.1 - 1.2e-05 25.4 0.2 0.0087 16.1 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KFM24907.1 - 1.7e-05 25.0 0.1 8.7e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KFM24907.1 - 3.2e-05 23.2 0.4 6.7e-05 22.1 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 KFM24907.1 - 4.2e-05 22.6 0.1 0.023 13.5 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase HI0933_like PF03486.14 KFM24907.1 - 0.00027 19.7 0.4 0.00043 19.1 0.1 1.4 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 KFM24907.1 - 0.00036 20.0 0.0 0.00062 19.2 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KFM24907.1 - 0.00063 19.1 0.6 0.0011 18.3 0.2 1.5 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 KFM24907.1 - 0.0012 18.0 0.0 0.0017 17.5 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KFM24907.1 - 0.0025 17.1 0.0 0.0039 16.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KFM24907.1 - 0.013 14.8 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.6 KFM24907.1 - 0.014 15.9 0.0 0.028 14.9 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain K_oxygenase PF13434.6 KFM24907.1 - 0.019 14.1 0.0 0.03 13.5 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.18 KFM24907.1 - 0.038 13.9 0.0 0.061 13.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KFM24907.1 - 0.077 12.3 0.3 0.13 11.5 0.3 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 KFM24907.1 - 0.094 13.2 0.0 0.17 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.18 KFM24907.1 - 0.12 12.6 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 KFM24907.1 - 0.21 11.1 0.1 0.32 10.6 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TetR_C_33 PF13305.6 KFM24908.1 - 0.41 11.4 4.8 0.19 12.5 1.6 2.1 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Chorismate_bind PF00425.18 KFM24909.1 - 4.2e-84 282.1 0.0 6e-84 281.6 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 KFM24909.1 - 3.3e-38 131.4 0.0 4.5e-38 130.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 KFM24909.1 - 6.3e-10 39.4 0.0 1.7e-09 38.1 0.0 1.7 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 KFM24909.1 - 3e-07 30.4 0.4 6e-07 29.4 0.4 1.4 1 1 0 1 1 1 1 Peptidase C26 GATase_3 PF07685.14 KFM24910.1 - 7.8e-25 87.6 0.0 1.2e-24 87.0 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain CbiA PF01656.23 KFM24910.1 - 2.5e-17 63.1 0.0 1.6e-16 60.5 0.0 2.0 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.6 KFM24910.1 - 4.4e-15 56.0 0.3 8.8e-07 28.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain Peripla_BP_2 PF01497.18 KFM24910.1 - 0.0001 21.9 0.2 0.008 15.8 0.2 2.7 1 1 0 1 1 1 1 Periplasmic binding protein LpxK PF02606.14 KFM24910.1 - 0.072 12.2 0.5 0.11 11.6 0.5 1.2 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase CTP_synth_N PF06418.14 KFM24910.1 - 0.092 12.0 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 CTP synthase N-terminus MobB PF03205.14 KFM24910.1 - 0.098 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B CBP_BcsQ PF06564.12 KFM24910.1 - 0.1 12.1 0.0 0.32 10.4 0.1 1.7 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ DUF1611 PF07755.11 KFM24910.1 - 0.15 11.3 5.1 0.029 13.7 0.7 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1611_C) P-loop domain ParA PF10609.9 KFM24910.1 - 0.51 9.8 2.1 0.8 9.1 2.1 1.2 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Frataxin_Cyay PF01491.16 KFM24911.1 - 9.4e-30 102.9 0.0 1e-29 102.8 0.0 1.0 1 0 0 1 1 1 1 Frataxin-like domain Pex2_Pex12 PF04757.14 KFM24912.1 - 7.2e-31 107.5 0.1 9.2e-31 107.2 0.1 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 KFM24912.1 - 0.14 12.1 6.9 0.27 11.1 6.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM24912.1 - 0.17 11.8 6.9 0.28 11.1 6.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2180 PF09947.9 KFM24912.1 - 0.24 11.4 5.0 0.47 10.5 5.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2180) Prok-RING_4 PF14447.6 KFM24912.1 - 0.57 10.1 9.2 0.94 9.4 9.2 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KFM24912.1 - 0.62 10.1 8.3 1.3 9.0 8.3 1.6 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 KFM24912.1 - 1.5 9.2 7.6 2.1 8.7 7.1 1.5 1 1 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 KFM24912.1 - 2.2 8.4 7.3 4.2 7.5 7.3 1.4 1 0 0 1 1 1 0 RING-type zinc-finger VWA_2 PF13519.6 KFM24913.1 - 1.4e-14 54.6 0.0 4.1e-14 53.1 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain AAA_lid_2 PF17863.1 KFM24913.1 - 7.4e-14 51.3 1.3 2.5e-13 49.6 1.3 2.0 1 0 0 1 1 1 1 AAA lid domain VWA PF00092.28 KFM24913.1 - 1.3e-08 35.3 0.0 2.2e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Mg_chelatase PF01078.21 KFM24913.1 - 0.012 14.9 1.4 0.028 13.8 1.3 1.7 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI VWA_3 PF13768.6 KFM24913.1 - 0.023 14.6 0.0 0.15 12.0 0.0 2.2 2 0 0 2 2 2 0 von Willebrand factor type A domain Mg_chelatase_C PF13335.6 KFM24913.1 - 0.026 15.1 2.4 0.09 13.4 2.4 1.9 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI C-terminal VWA_CoxE PF05762.14 KFM24913.1 - 0.049 13.0 0.7 0.65 9.4 0.0 2.7 3 0 0 3 3 3 0 VWA domain containing CoxE-like protein AAA_lid_8 PF17868.1 KFM24913.1 - 0.079 12.9 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 AAA lid domain Peptidase_M41 PF01434.18 KFM24914.1 - 9e-57 192.0 1.0 2.8e-56 190.4 1.0 1.7 1 1 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KFM24914.1 - 3.8e-42 143.8 0.0 9.6e-42 142.5 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFM24914.1 - 9e-12 44.6 0.2 2.4e-11 43.2 0.2 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KFM24914.1 - 1.8e-06 28.0 0.0 6.4e-06 26.2 0.0 2.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFM24914.1 - 8.3e-06 26.3 0.0 0.0033 17.8 0.3 2.9 1 1 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 KFM24914.1 - 0.0014 17.9 0.0 0.0024 17.2 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 KFM24914.1 - 0.0026 17.5 0.0 0.0063 16.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KFM24914.1 - 0.0027 18.0 0.0 0.06 13.6 0.1 2.4 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KFM24914.1 - 0.017 14.9 0.1 0.041 13.6 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 KFM24914.1 - 0.021 15.1 0.0 0.044 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KFM24914.1 - 0.028 13.8 0.2 0.069 12.5 0.2 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KFM24914.1 - 0.029 14.9 0.0 0.052 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KFM24914.1 - 0.043 14.0 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KFM24914.1 - 0.062 13.3 0.1 0.17 11.9 0.1 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_2 PF07724.14 KFM24914.1 - 0.068 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 KFM24914.1 - 0.088 12.3 0.1 0.5 9.8 0.1 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 KFM24914.1 - 0.15 11.4 0.0 0.42 9.9 0.1 1.7 2 0 0 2 2 2 0 KaiC GCP_C_terminal PF04130.13 KFM24916.1 - 3.1e-51 174.7 0.0 4.7e-51 174.1 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KFM24916.1 - 1.9e-48 165.7 0.0 3.7e-48 164.7 0.0 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal TIP41 PF04176.13 KFM24917.1 - 6.5e-49 165.7 0.0 9.2e-49 165.2 0.0 1.2 1 0 0 1 1 1 1 TIP41-like family Tudor_4 PF18358.1 KFM24917.1 - 0.13 11.9 0.1 0.36 10.5 0.0 1.7 2 0 0 2 2 2 0 Histone methyltransferase Tudor domain Y_phosphatase3 PF13350.6 KFM24918.1 - 4.3e-27 95.6 0.1 5.7e-27 95.2 0.1 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KFM24918.1 - 3e-05 23.7 0.0 6e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KFM24918.1 - 8.7e-05 22.2 0.0 0.00014 21.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Myotub-related PF06602.14 KFM24918.1 - 0.0058 15.6 0.0 0.0087 15.0 0.0 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.20 KFM24918.1 - 0.031 14.1 0.0 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Peptidase_C78 PF07910.13 KFM24919.1 - 1.2e-43 149.0 0.0 1.6e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C54 PF03416.19 KFM24919.1 - 0.061 12.7 0.0 0.16 11.4 0.0 1.6 2 0 0 2 2 2 0 Peptidase family C54 CKS PF01111.19 KFM24920.1 - 1.3e-29 102.2 0.1 1.6e-29 102.0 0.1 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit NPL4 PF05021.15 KFM24921.1 - 7.6e-20 71.5 0.0 3.7e-09 36.4 0.0 3.2 2 1 1 3 3 3 3 NPL4 family UN_NPL4 PF11543.8 KFM24921.1 - 2.1e-09 37.8 0.0 1.1e-08 35.5 0.0 2.3 2 1 0 2 2 2 1 Nuclear pore localisation protein NPL4 ParcG PF10274.9 KFM24922.1 - 2.4e-39 135.3 0.0 1.2e-32 113.5 0.0 2.0 2 0 0 2 2 2 2 Parkin co-regulated protein Pkinase PF00069.25 KFM24923.1 - 2.5e-47 161.5 0.0 6e-47 160.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM24923.1 - 8.2e-31 107.2 0.0 2.9e-30 105.4 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM24923.1 - 4e-05 23.1 0.0 8.4e-05 22.0 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFM24923.1 - 0.00044 19.7 0.2 0.00085 18.7 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KFM24923.1 - 0.0029 17.3 0.2 2.3 7.8 0.0 2.1 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KFM24923.1 - 0.0047 16.9 0.7 0.38 10.6 0.2 2.5 1 1 0 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KFM24923.1 - 0.15 11.6 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pkinase_fungal PF17667.1 KFM24923.1 - 0.2 10.4 0.0 0.29 9.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KFM24923.1 - 0.21 10.5 0.1 0.29 10.1 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 KFM24924.1 - 2e-46 158.5 0.0 8.2e-46 156.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain EF-hand_1 PF00036.32 KFM24924.1 - 9.7e-23 78.0 0.1 1.3e-05 24.4 0.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KFM24924.1 - 1.6e-20 73.4 0.8 2.3e-09 37.5 0.3 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KFM24924.1 - 1.4e-18 65.5 2.5 0.0003 20.2 0.0 4.7 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KFM24924.1 - 1.1e-17 63.6 0.6 0.00013 21.8 0.0 4.9 4 1 1 5 5 5 4 EF-hand domain pair EF-hand_6 PF13405.6 KFM24924.1 - 2e-17 61.5 0.7 0.00032 20.4 0.1 4.8 4 0 0 4 4 4 4 EF-hand domain Pkinase_Tyr PF07714.17 KFM24924.1 - 1.4e-15 57.3 0.0 2.9e-15 56.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase SPARC_Ca_bdg PF10591.9 KFM24924.1 - 0.00032 21.0 0.0 0.31 11.4 0.0 2.7 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KFM24924.1 - 0.027 14.8 0.0 0.75 10.2 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain GNAT_acetyltr_2 PF13718.6 KFM24925.1 - 1.8e-87 292.5 0.0 2.9e-87 291.8 0.0 1.3 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 KFM24925.1 - 3.6e-55 187.2 0.0 5.4e-55 186.6 0.0 1.3 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 KFM24925.1 - 5.2e-55 186.0 0.0 1.9e-54 184.2 0.0 2.0 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 KFM24925.1 - 1.5e-32 111.4 0.0 3.1e-32 110.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_22 PF13401.6 KFM24925.1 - 0.0096 16.2 0.0 1.7 8.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain SET PF00856.28 KFM24926.1 - 1.7e-12 48.1 0.0 2.8e-12 47.3 0.0 1.4 1 1 0 1 1 1 1 SET domain SAF PF08666.12 KFM24926.1 - 0.012 16.2 0.7 0.92 10.2 0.0 2.8 3 0 0 3 3 3 0 SAF domain DUF1454 PF07305.12 KFM24926.1 - 0.2 11.1 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1454) FKBP_C PF00254.28 KFM24927.1 - 1.6e-60 201.4 0.1 2.3e-33 114.4 0.0 3.4 3 0 0 3 3 3 3 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_2 PF07719.17 KFM24927.1 - 2.9e-09 36.3 0.5 0.06 13.5 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFM24927.1 - 2.3e-08 33.5 0.1 0.012 15.4 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat FKBP_N_2 PF18023.1 KFM24927.1 - 0.00031 20.8 0.0 2.4 8.3 0.0 3.6 3 2 0 3 3 3 2 BDBT FKBP like N-terminal TPR_16 PF13432.6 KFM24927.1 - 0.00038 21.0 9.9 0.0078 16.8 0.1 3.1 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFM24927.1 - 0.015 15.0 0.8 0.15 11.8 0.1 2.8 3 0 0 3 3 3 0 TPR repeat Fis1_TPR_C PF14853.6 KFM24927.1 - 0.025 14.7 0.0 4 7.6 0.0 2.5 1 1 1 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.6 KFM24927.1 - 0.026 15.0 0.1 0.17 12.4 0.0 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFM24927.1 - 0.06 14.2 1.6 35 5.6 0.4 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFM24927.1 - 0.072 13.3 0.0 0.93 9.9 0.0 2.6 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFM24927.1 - 0.13 12.5 0.7 9.2 6.6 0.2 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat CoA_trans PF01144.23 KFM24928.1 - 2.9e-30 105.3 0.1 9.1e-30 103.7 0.0 1.9 2 0 0 2 2 2 1 Coenzyme A transferase Mal_decarbox_Al PF16957.5 KFM24928.1 - 0.0091 14.4 0.0 0.014 13.7 0.0 1.2 1 0 0 1 1 1 1 Malonate decarboxylase, alpha subunit, transporter MORN PF02493.20 KFM24929.1 - 2e-57 187.8 72.7 5.7e-07 29.0 0.1 13.8 14 0 0 14 14 14 13 MORN repeat Filamin PF00630.19 KFM24929.1 - 8.2e-29 100.5 0.0 7.1e-18 65.3 0.0 3.0 3 0 0 3 3 3 2 Filamin/ABP280 repeat Invasin_D3 PF09134.10 KFM24929.1 - 0.011 16.0 0.0 0.059 13.7 0.2 2.0 2 0 0 2 2 2 0 Invasin, domain 3 Bmp PF02608.14 KFM24929.1 - 0.077 12.0 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 ABC transporter substrate-binding protein PnrA-like PLAC8 PF04749.17 KFM24930.1 - 2e-08 35.1 9.4 4.1e-08 34.1 9.4 1.6 1 1 0 1 1 1 1 PLAC8 family RNase_J_C PF17770.1 KFM24930.1 - 0.015 16.3 0.0 0.028 15.4 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease J C-terminal domain AAA_12 PF13087.6 KFM24931.1 - 1e-56 191.7 0.0 1.7e-56 191.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFM24931.1 - 2.2e-55 188.3 0.0 2.9e-55 187.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFM24931.1 - 6e-09 35.9 1.2 0.0019 18.0 0.1 3.0 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 KFM24931.1 - 3.8e-06 27.3 0.1 0.039 14.3 0.1 3.0 2 1 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 KFM24931.1 - 2.2e-05 24.3 0.0 0.064 13.0 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 KFM24931.1 - 0.00078 19.2 0.0 0.0022 17.8 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA PF00004.29 KFM24931.1 - 0.0026 18.2 0.2 0.047 14.1 0.1 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFM24931.1 - 0.07 13.4 0.0 0.21 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 KFM24931.1 - 0.11 12.0 0.0 11 5.4 0.0 3.0 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 KFM24931.1 - 0.16 12.3 5.8 0.83 10.0 2.5 3.6 3 1 0 3 3 3 0 AAA ATPase domain TPR_11 PF13414.6 KFM24932.1 - 0.0052 16.4 4.3 2.2 8.0 0.1 4.3 4 0 0 4 4 4 1 TPR repeat TPR_17 PF13431.6 KFM24932.1 - 0.012 16.0 0.0 20 5.8 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TOM20_plant PF06552.12 KFM24932.1 - 0.013 15.3 0.0 0.041 13.6 0.0 1.8 2 0 0 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_19 PF14559.6 KFM24932.1 - 0.17 12.4 0.2 0.17 12.4 0.2 5.9 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFM24932.1 - 0.44 10.8 10.2 2 8.7 0.2 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF2854 PF11016.8 KFM24933.1 - 8.7e-43 145.7 0.0 1.3e-42 145.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2854) WD40 PF00400.32 KFM24935.1 - 6.4e-11 42.6 2.7 0.022 15.6 0.0 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat Pkinase PF00069.25 KFM24937.1 - 6.4e-68 229.0 0.0 9.2e-68 228.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM24937.1 - 1.3e-26 93.4 0.0 1.8e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 KFM24937.1 - 4.9e-24 82.0 4.1 5.1e-06 25.7 0.1 4.7 3 1 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KFM24937.1 - 1.8e-23 82.8 3.9 3.6e-10 40.2 0.4 3.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KFM24937.1 - 5.6e-19 66.4 4.9 3.4e-05 23.4 0.1 5.0 3 1 1 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 KFM24937.1 - 6.9e-19 66.4 4.6 3.1e-05 23.3 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KFM24937.1 - 8.9e-15 54.3 2.0 0.0015 18.3 0.0 4.6 3 1 1 4 4 4 3 EF-hand domain pair Kinase-like PF14531.6 KFM24937.1 - 4.4e-08 32.8 0.0 4.6e-07 29.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KFM24937.1 - 0.0012 17.8 0.0 0.0023 16.8 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase EF-hand_4 PF12763.7 KFM24937.1 - 0.013 15.4 0.4 3.3 7.7 0.1 3.1 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand Kdo PF06293.14 KFM24937.1 - 0.018 14.4 0.0 0.046 13.1 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SPARC_Ca_bdg PF10591.9 KFM24937.1 - 0.047 14.0 0.1 6.3 7.2 0.1 2.4 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region APH PF01636.23 KFM24937.1 - 0.048 13.6 0.0 0.26 11.2 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Dockerin_1 PF00404.18 KFM24937.1 - 0.46 10.7 2.6 61 3.9 0.8 3.7 2 1 1 3 3 3 0 Dockerin type I domain PAP2 PF01569.21 KFM24938.1 - 5e-17 61.9 6.3 5e-17 61.9 6.3 1.7 1 1 1 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 KFM24938.1 - 2.1e-05 24.3 14.3 0.00011 21.9 14.4 2.0 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 KFM24938.1 - 0.00082 19.9 0.9 0.002 18.6 0.2 1.9 2 0 0 2 2 2 1 PAP2 superfamily C-terminal CTP_transf_like PF01467.26 KFM24939.1 - 5e-32 111.1 0.1 1e-31 110.0 0.0 1.6 2 0 0 2 2 2 1 Cytidylyltransferase-like DUF5639 PF18690.1 KFM24939.1 - 0.01 16.0 0.1 0.035 14.3 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5639) Metalloenzyme PF01676.18 KFM24940.1 - 3.8e-78 262.3 0.0 4.3e-78 262.1 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.13 KFM24940.1 - 8.3e-57 192.1 0.0 1.1e-56 191.7 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.22 KFM24940.1 - 0.00099 18.8 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Glyco_transf_64 PF09258.10 KFM24944.1 - 3.7e-43 147.6 0.0 5.3e-43 147.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Calmodulin_bind PF07887.11 KFM24945.1 - 2.8e-10 40.0 0.0 1.6e-09 37.5 0.0 1.9 1 1 0 1 1 1 1 Calmodulin binding protein-like FA_hydroxylase PF04116.13 KFM24946.1 - 1.3e-12 48.2 0.6 2.2e-12 47.5 0.6 1.3 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily GHMP_kinases_C PF08544.13 KFM24946.1 - 0.072 13.5 0.2 0.17 12.3 0.2 1.6 1 0 0 1 1 1 0 GHMP kinases C terminal Ribophorin_II PF05817.14 KFM24948.1 - 2.4e-27 95.8 0.0 3e-27 95.5 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Aminotran_4 PF01063.19 KFM24949.1 - 9.1e-29 100.9 0.0 1.3e-28 100.4 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV Myb_DNA-binding PF00249.31 KFM24951.1 - 6.4e-07 29.5 0.2 1.2e-06 28.6 0.2 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFM24951.1 - 7e-05 23.0 0.0 0.00012 22.3 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF3584 PF12128.8 KFM24952.1 - 0.00032 18.4 7.9 0.00043 18.0 7.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.12 KFM24952.1 - 0.00099 19.2 2.6 0.37 10.8 0.2 3.5 1 1 2 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus SF-assemblin PF06705.11 KFM24952.1 - 0.004 16.6 0.1 0.53 9.6 0.2 2.8 1 1 2 3 3 3 1 SF-assemblin/beta giardin EzrA PF06160.12 KFM24952.1 - 0.055 11.6 0.5 0.087 11.0 0.5 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA HAMP PF00672.25 KFM24952.1 - 0.082 13.3 0.7 0.082 13.3 0.7 4.0 3 2 1 4 4 4 0 HAMP domain DUF5344 PF17279.2 KFM24952.1 - 0.19 12.3 1.3 1.6 9.4 0.9 2.6 2 1 1 3 3 3 0 Family of unknown function (DUF5344) BLOC1_2 PF10046.9 KFM24952.1 - 0.24 11.7 2.8 26 5.2 0.1 3.9 3 3 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GrpE PF01025.19 KFM24952.1 - 0.34 10.6 6.4 1.8 8.2 1.0 2.6 1 1 1 2 2 2 0 GrpE DUF4618 PF15397.6 KFM24952.1 - 0.35 10.2 7.4 8.3 5.8 0.0 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) Apolipoprotein PF01442.18 KFM24952.1 - 0.37 10.6 37.0 0.46 10.3 25.8 2.6 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain Collagen_mid PF15984.5 KFM24952.1 - 0.46 10.2 5.4 0.51 10.1 1.7 2.5 2 1 1 3 3 3 0 Bacterial collagen, middle region CCDC-167 PF15188.6 KFM24952.1 - 0.47 10.8 6.9 25 5.3 4.0 3.5 3 1 0 4 4 4 0 Coiled-coil domain-containing protein 167 Spc7 PF08317.11 KFM24952.1 - 0.47 9.3 7.7 3.6 6.4 7.4 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Corona_S2 PF01601.16 KFM24952.1 - 0.47 8.9 0.5 0.75 8.2 0.5 1.4 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Trimer_CC PF08954.11 KFM24952.1 - 0.55 9.8 9.1 1 9.0 0.0 4.2 4 1 0 4 4 4 0 Trimerisation motif SLX9 PF15341.6 KFM24952.1 - 0.7 10.3 4.2 7.3 7.0 1.0 2.3 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 CLZ PF16526.5 KFM24952.1 - 1.2 9.5 13.1 59 4.1 0.0 4.1 3 1 1 4 4 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SlyX PF04102.12 KFM24952.1 - 3.5 8.3 20.1 40 4.9 1.0 5.9 3 1 2 5 5 5 0 SlyX Exonuc_VII_L PF02601.15 KFM24952.1 - 3.7 7.0 11.5 11 5.5 11.5 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit FlxA PF14282.6 KFM24952.1 - 5.3 7.1 10.7 1.7 8.6 0.6 2.7 1 1 2 3 3 3 0 FlxA-like protein zf-CCCH PF00642.24 KFM24953.1 - 8e-11 41.6 1.4 1.5e-10 40.7 1.4 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KFM24953.1 - 4.4e-08 32.7 4.2 6.5e-08 32.2 4.2 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KFM24953.1 - 3.9e-06 26.7 4.9 6.9e-06 25.9 4.9 1.5 1 0 0 1 1 1 1 Zinc finger domain WW PF00397.26 KFM24953.1 - 6.8e-05 22.9 2.4 6.8e-05 22.9 2.4 2.0 2 0 0 2 2 2 1 WW domain Torus PF16131.5 KFM24953.1 - 0.0068 17.1 0.3 0.01 16.5 0.3 1.3 1 0 0 1 1 1 1 Torus domain zf-CCCH_3 PF15663.5 KFM24953.1 - 0.04 14.1 0.3 0.064 13.5 0.3 1.3 1 0 0 1 1 1 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 KFM24953.1 - 0.056 13.9 1.1 0.11 13.1 1.1 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger oligo_HPY PF08352.12 KFM24953.1 - 0.12 12.9 0.3 0.2 12.2 0.3 1.4 1 0 0 1 1 1 0 Oligopeptide/dipeptide transporter, C-terminal region PP2C PF00481.21 KFM24954.1 - 1.6e-13 50.9 0.0 5.8e-06 26.1 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 KFM24954.1 - 2.9e-13 50.2 0.1 5.3e-13 49.3 0.1 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KFM24954.1 - 9.9e-07 28.6 2.7 4.2e-06 26.6 2.7 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C SH2_2 PF14633.6 KFM24955.1 - 1.9e-35 122.3 0.0 3.3e-19 69.2 0.0 2.2 2 0 0 2 2 2 2 SH2 domain SPT6_acidic PF14632.6 KFM24955.1 - 1.4e-10 41.6 10.1 1.4e-10 41.6 10.1 3.0 2 1 2 4 4 4 1 Acidic N-terminal SPT6 DUF667 PF05018.13 KFM24956.1 - 6.7e-68 228.1 0.1 7.7e-68 227.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) Pentapeptide_2 PF01469.18 KFM24958.1 - 0.0011 18.8 11.5 0.0011 18.8 11.5 1.9 2 0 0 2 2 2 1 Pentapeptide repeats (8 copies) OrfB_Zn_ribbon PF07282.11 KFM24959.1 - 0.0097 15.8 4.3 0.03 14.2 4.3 1.8 1 1 0 1 1 1 1 Putative transposase DNA-binding domain La PF05383.17 KFM24960.1 - 8.9e-20 70.5 0.0 1.7e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 KFM24960.1 - 5e-08 32.6 0.3 7.9e-07 28.8 0.0 2.5 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFM24960.1 - 0.00035 20.6 0.0 0.0033 17.4 0.0 2.3 2 0 0 2 2 2 1 RNA binding motif RSN1_7TM PF02714.15 KFM24963.1 - 1.8e-42 145.6 11.5 1.8e-42 145.6 11.5 1.6 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KFM24963.1 - 2.7e-25 89.0 3.2 1.6e-24 86.5 3.2 2.3 1 1 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KFM24963.1 - 1.7e-07 31.7 0.0 5.4e-07 30.0 0.0 1.8 2 0 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter HLH PF00010.26 KFM24963.1 - 0.24 11.4 0.6 0.66 10.0 0.6 1.7 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain AAA PF00004.29 KFM24966.1 - 4.5e-42 143.6 0.0 7.9e-42 142.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFM24966.1 - 1e-12 47.6 0.3 2e-12 46.7 0.3 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KFM24966.1 - 7.1e-07 29.1 0.5 1.6e-06 27.9 0.5 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 KFM24966.1 - 6.6e-06 26.3 0.0 4.7e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KFM24966.1 - 8.1e-06 25.9 0.0 3.8e-05 23.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFM24966.1 - 1.9e-05 25.1 0.1 0.00056 20.3 0.0 2.7 2 1 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 KFM24966.1 - 0.0005 19.8 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KFM24966.1 - 0.00064 20.0 1.0 0.021 15.1 0.0 2.6 2 1 1 3 3 2 1 AAA domain Mg_chelatase PF01078.21 KFM24966.1 - 0.0027 17.1 0.1 0.03 13.7 0.1 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KFM24966.1 - 0.003 17.7 0.0 0.0068 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KFM24966.1 - 0.0034 17.1 0.0 0.0078 16.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 KFM24966.1 - 0.0076 15.5 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain HR1 PF02185.16 KFM24966.1 - 0.012 15.7 1.6 0.032 14.3 1.6 1.8 1 0 0 1 1 1 0 Hr1 repeat DUF815 PF05673.13 KFM24966.1 - 0.012 14.8 0.0 0.024 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_3 PF07726.11 KFM24966.1 - 0.013 15.4 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KFM24966.1 - 0.014 15.9 0.0 0.04 14.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KFM24966.1 - 0.016 15.6 0.1 0.61 10.4 0.1 2.8 3 0 0 3 3 3 0 AAA domain PhoH PF02562.16 KFM24966.1 - 0.019 14.5 0.0 0.16 11.4 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein DUF2072 PF09845.9 KFM24966.1 - 0.019 15.2 0.3 0.043 14.1 0.3 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein AAA_11 PF13086.6 KFM24966.1 - 0.022 14.5 0.8 0.17 11.7 0.1 2.5 2 1 0 3 3 3 0 AAA domain AAA_28 PF13521.6 KFM24966.1 - 0.025 14.9 0.0 0.055 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Prot_ATP_OB_N PF17758.1 KFM24966.1 - 0.032 13.9 0.0 0.11 12.1 0.0 2.0 2 0 0 2 2 1 0 Proteasomal ATPase OB N-terminal domain ERM PF00769.19 KFM24966.1 - 0.032 14.1 0.5 0.062 13.1 0.5 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family ATPase PF06745.13 KFM24966.1 - 0.036 13.4 0.0 0.083 12.2 0.0 1.6 1 0 0 1 1 1 0 KaiC Sigma54_activat PF00158.26 KFM24966.1 - 0.04 13.6 0.2 0.17 11.6 0.0 2.1 2 1 0 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 KFM24966.1 - 0.053 12.6 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_24 PF13479.6 KFM24966.1 - 0.057 13.1 0.0 0.15 11.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 KFM24966.1 - 0.059 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KFM24966.1 - 0.077 12.5 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF1090 PF06476.12 KFM24966.1 - 0.078 13.1 4.0 0.61 10.2 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) MscS_porin PF12795.7 KFM24966.1 - 0.099 12.2 3.4 0.17 11.4 3.4 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain AAA_17 PF13207.6 KFM24966.1 - 0.1 13.0 0.2 0.3 11.5 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 KFM24966.1 - 0.1 12.1 0.0 0.36 10.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 KFM24966.1 - 0.11 12.4 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 KFM24966.1 - 0.14 12.6 0.0 0.31 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TolA_bind_tri PF16331.5 KFM24966.1 - 0.75 9.9 8.8 0.45 10.6 5.4 2.2 2 0 0 2 2 2 0 TolA binding protein trimerisation DivIC PF04977.15 KFM24966.1 - 7.6 6.4 6.3 3 7.7 3.5 1.7 2 0 0 2 2 1 0 Septum formation initiator Chloroa_b-bind PF00504.21 KFM24968.1 - 6.1e-36 124.4 0.1 7.7e-36 124.1 0.1 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein CobD_Cbib PF03186.13 KFM24968.1 - 0.047 12.9 0.0 0.068 12.4 0.0 1.2 1 0 0 1 1 1 0 CobD/Cbib protein Abhydrolase_1 PF00561.20 KFM24970.1 - 2e-16 60.4 0.0 5.7e-16 58.9 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFM24970.1 - 1.7e-08 35.4 6.0 2.3e-08 34.9 6.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFM24970.1 - 1e-07 31.5 0.2 5.1e-07 29.2 0.2 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KFM24970.1 - 0.011 15.2 0.0 0.33 10.4 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Sdh_cyt PF01127.22 KFM24970.1 - 0.021 14.8 0.0 0.19 11.8 0.0 2.2 2 0 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Ndr PF03096.14 KFM24970.1 - 0.24 10.0 0.0 0.36 9.5 0.0 1.2 1 0 0 1 1 1 0 Ndr family ECH_1 PF00378.20 KFM24971.1 - 1.1e-63 214.9 0.0 5.6e-51 173.3 0.0 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFM24971.1 - 5.7e-11 42.5 0.0 9.4e-05 22.1 0.0 2.4 2 1 1 3 3 3 2 Enoyl-CoA hydratase/isomerase SDH_sah PF01972.16 KFM24971.1 - 4.9e-05 22.5 0.0 6.8e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Serine dehydrogenase proteinase Ceramidase_alk PF04734.13 KFM24972.1 - 1.7e-204 680.2 0.0 2.1e-204 679.9 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 KFM24972.1 - 1.9e-49 167.7 0.1 3e-49 167.1 0.1 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal PMI_typeI PF01238.21 KFM24973.1 - 2.9e-73 247.2 0.0 1.1e-45 156.4 0.0 2.2 1 1 1 2 2 2 2 Phosphomannose isomerase type I DUF1850 PF08905.11 KFM24973.1 - 0.0072 16.6 0.0 0.3 11.4 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1850) Cupin_2 PF07883.11 KFM24973.1 - 0.15 11.8 0.0 0.48 10.2 0.0 1.8 2 0 0 2 2 2 0 Cupin domain SH3_16 PF18348.1 KFM24974.1 - 0.055 13.3 0.4 0.23 11.3 0.0 2.2 2 0 0 2 2 2 0 Bacterial dipeptidyl-peptidase Sh3 domain AAA_33 PF13671.6 KFM24977.1 - 6.1e-05 23.2 0.0 0.0001 22.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFM24977.1 - 0.00088 19.7 0.1 0.0021 18.5 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 KFM24977.1 - 0.044 13.5 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KFM24977.1 - 0.053 14.1 0.0 0.087 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KFM24977.1 - 0.087 12.1 0.0 0.34 10.2 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin RcbX PF02341.15 KFM24978.1 - 0.0027 17.9 0.1 0.0035 17.6 0.1 1.2 1 0 0 1 1 1 1 RbcX protein tRNA-synt_1e PF01406.19 KFM24979.1 - 8.6e-119 396.4 0.0 1.1e-117 392.7 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KFM24979.1 - 2.8e-06 26.3 0.2 0.0035 16.1 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KFM24979.1 - 0.043 12.0 0.0 0.15 10.3 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 KFM24979.1 - 0.049 12.5 0.1 7.5 5.4 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (K) IGF2_C PF08365.11 KFM24979.1 - 3.1 7.9 10.2 8.1 6.5 4.3 3.6 3 0 0 3 3 3 0 Insulin-like growth factor II E-peptide KH_1 PF00013.29 KFM24980.1 - 2.6e-18 65.6 0.0 5.5e-05 22.9 0.0 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KFM24980.1 - 4.4e-08 32.8 0.0 0.03 14.1 0.0 3.1 2 1 1 3 3 3 3 KH domain KH_4 PF13083.6 KFM24980.1 - 0.00024 20.9 0.0 3.4 7.6 0.0 3.4 3 0 0 3 3 3 2 KH domain KH_5 PF13184.6 KFM24980.1 - 0.0058 16.7 0.9 2.7 8.1 0.0 3.1 4 0 0 4 4 4 2 NusA-like KH domain DUF5437 PF17505.2 KFM24980.1 - 0.24 11.5 1.5 0.62 10.1 1.5 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5437) DUF1174 PF06671.11 KFM24981.1 - 7.5 6.4 6.6 12 5.7 0.4 2.3 2 0 0 2 2 2 0 Repeat of unknown function (DUF1174) UQ_con PF00179.26 KFM24983.1 - 5.3e-19 68.3 0.0 3.4e-17 62.4 0.0 2.0 1 1 1 2 2 2 2 Ubiquitin-conjugating enzyme RWD PF05773.22 KFM24983.1 - 0.11 12.8 0.0 0.13 12.6 0.0 1.4 1 1 0 1 1 1 0 RWD domain PAN_4 PF14295.6 KFM24984.1 - 0.0019 18.1 4.1 0.36 10.8 1.8 2.5 2 0 0 2 2 2 2 PAN domain Bromodomain PF00439.25 KFM24985.1 - 2.4e-20 72.4 0.0 3.3e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 KFM24985.1 - 2.7e-05 24.3 0.0 3.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation RRN3 PF05327.11 KFM24986.1 - 6.7e-51 173.5 0.0 3e-38 131.7 0.0 4.0 3 1 1 4 4 4 3 RNA polymerase I specific transcription initiation factor RRN3 AF-4 PF05110.13 KFM24986.1 - 0.64 8.0 14.4 0.84 7.6 14.4 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DNA_pol_phi PF04931.13 KFM24986.1 - 4.9 5.1 7.0 7.4 4.5 7.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi Peptidase_M20 PF01546.28 KFM24987.1 - 7.1e-32 110.8 0.0 2.3e-31 109.1 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KFM24987.1 - 7.7e-09 35.4 0.0 2.2e-08 34.0 0.0 1.7 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KFM24987.1 - 0.017 14.9 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 Pkinase PF00069.25 KFM24988.1 - 1.2e-06 28.1 0.0 0.00097 18.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain PSRP-3_Ycf65 PF04839.13 KFM24989.1 - 5.9e-20 71.2 1.8 9.5e-20 70.5 1.8 1.3 1 0 0 1 1 1 1 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) UPF0016 PF01169.19 KFM24990.1 - 1.9e-25 89.0 10.9 1.6e-16 60.4 6.8 2.5 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 UPF0016 PF01169.19 KFM24991.1 - 5.7e-08 33.0 5.7 7.3e-08 32.6 5.7 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0016 KN17_SH3 PF18131.1 KFM24992.1 - 0.0091 16.1 1.1 0.019 15.1 0.3 1.9 2 0 0 2 2 2 1 KN17 SH3-like C-terminal domain PP2C PF00481.21 KFM24993.1 - 8.6e-25 87.8 0.2 1.3e-19 70.9 0.1 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C IMS PF00817.20 KFM24994.1 - 8.4e-27 94.0 0.0 7.7e-24 84.4 0.0 2.6 1 1 0 1 1 1 1 impB/mucB/samB family C2 PF00168.30 KFM24994.1 - 2.1e-20 72.9 0.0 5.9e-19 68.3 0.0 2.7 3 0 0 3 3 3 1 C2 domain IMS_C PF11799.8 KFM24994.1 - 2.8e-12 47.4 0.6 6.5e-12 46.2 0.1 1.8 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KFM24994.1 - 6.5e-06 26.2 0.0 2.4e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 IMS family HHH motif zf-RanBP PF00641.18 KFM24994.1 - 0.019 14.3 0.3 0.04 13.2 0.3 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others GSG-1 PF07803.11 KFM24994.1 - 0.11 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 GSG1-like protein SMP_LBD PF17047.5 KFM24994.1 - 0.15 11.5 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Synaptotagmin-like mitochondrial-lipid-binding domain Pmp3 PF01679.17 KFM24995.1 - 6.5e-23 80.7 6.0 7.2e-23 80.5 6.0 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator SBP PF03110.14 KFM24996.1 - 2e-20 72.9 1.9 3.1e-20 72.2 1.9 1.3 1 0 0 1 1 1 1 SBP domain AP2 PF00847.20 KFM24998.1 - 2.6e-12 46.8 3.0 2.6e-12 46.8 3.0 2.5 3 0 0 3 3 3 1 AP2 domain TFIIA PF03153.13 KFM24998.1 - 5.9 6.8 8.8 8.4 6.3 8.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LRR_6 PF13516.6 KFM24999.1 - 1.5e-06 27.8 2.6 0.0058 16.6 0.1 6.4 8 0 0 8 8 8 1 Leucine Rich repeat LRR_4 PF12799.7 KFM24999.1 - 5.9e-06 26.5 0.1 3.1 8.3 0.0 4.7 3 1 2 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM24999.1 - 0.0096 16.3 6.7 13 6.8 0.2 5.7 4 2 0 4 4 4 1 Leucine Rich Repeat LRR_8 PF13855.6 KFM24999.1 - 0.22 11.3 3.1 45 3.9 0.0 4.3 4 1 1 5 5 5 0 Leucine rich repeat Nuc_sug_transp PF04142.15 KFM25000.1 - 5.5e-09 35.6 6.3 2e-08 33.8 1.2 2.1 2 0 0 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.20 KFM25000.1 - 8e-08 32.5 1.8 8e-08 32.5 1.8 3.3 3 1 0 3 3 3 1 EamA-like transporter family CRT-like PF08627.10 KFM25000.1 - 6.1e-06 25.4 5.2 2.8e-05 23.2 3.2 2.2 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like PUNUT PF16913.5 KFM25000.1 - 3.1e-05 23.3 1.8 7.4e-05 22.1 1.8 1.6 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport SLC35F PF06027.12 KFM25000.1 - 0.001 18.6 5.0 0.001 18.6 5.0 1.8 2 0 0 2 2 2 1 Solute carrier family 35 MadM PF03818.13 KFM25001.1 - 0.026 14.4 3.3 1.6 8.6 0.2 2.6 2 0 0 2 2 2 0 Malonate/sodium symporter MadM subunit Shisa PF13908.6 KFM25001.1 - 1.6 9.0 11.9 0.067 13.4 6.0 1.8 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator NnrU PF07298.11 KFM25002.1 - 3e-43 147.8 12.9 4.4e-43 147.2 12.9 1.2 1 0 0 1 1 1 1 NnrU protein PEMT PF04191.13 KFM25002.1 - 0.023 15.1 0.1 0.023 15.1 0.1 2.3 4 0 0 4 4 4 0 Phospholipid methyltransferase LacAB_rpiB PF02502.18 KFM25003.1 - 4.4e-17 62.4 0.2 2e-16 60.2 0.2 1.8 1 1 0 1 1 1 1 Ribose/Galactose Isomerase HTH_29 PF13551.6 KFM25003.1 - 0.021 14.8 0.0 0.05 13.6 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix HTH_28 PF13518.6 KFM25003.1 - 0.13 12.4 0.1 0.31 11.2 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain Alg6_Alg8 PF03155.15 KFM25006.1 - 2.6e-153 511.5 20.3 3.1e-153 511.2 20.3 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family TetR_C_26 PF17934.1 KFM25006.1 - 0.32 11.3 0.7 0.59 10.5 0.7 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain OCRE PF17780.1 KFM25007.1 - 2.9e-13 49.6 1.8 5.8e-13 48.6 1.8 1.6 1 0 0 1 1 1 1 OCRE domain EFTUD2 PF16004.5 KFM25007.1 - 0.018 15.6 0.5 0.018 15.6 0.5 3.2 3 1 0 3 3 3 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus DAGK_acc PF00609.19 KFM25008.1 - 1.2e-35 123.2 0.0 3.6e-24 85.9 0.0 2.3 1 1 1 2 2 2 2 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 KFM25008.1 - 1.8e-18 66.4 0.1 3.4e-18 65.5 0.1 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Lactamase_B PF00753.27 KFM25008.1 - 1.4e-05 25.2 2.6 1.4e-05 25.2 2.6 2.1 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily C1_1 PF00130.22 KFM25008.1 - 1.9e-05 24.5 10.5 0.00028 20.7 1.9 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Lactamase_B_5 PF14597.6 KFM25008.1 - 0.00059 19.4 0.0 0.0013 18.3 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Fer4_13 PF13370.6 KFM25008.1 - 0.0011 19.5 0.1 0.0011 19.5 0.1 2.5 2 0 0 2 2 2 1 4Fe-4S single cluster domain of Ferredoxin I zf-RING_9 PF13901.6 KFM25008.1 - 2.5 8.0 9.5 1.6 8.7 2.4 2.2 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon zf-C3HC4_3 PF13920.6 KFM25009.1 - 1.3e-09 37.7 5.7 2.1e-09 37.1 5.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM25009.1 - 1.8e-08 34.1 8.7 2.7e-08 33.5 8.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFM25009.1 - 6.6e-08 32.5 7.8 2.8e-07 30.4 8.3 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFM25009.1 - 1.7e-07 31.4 10.8 2.6e-07 30.9 10.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFM25009.1 - 1.9e-07 30.8 9.3 3e-07 30.2 9.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM25009.1 - 2.9e-06 27.1 8.2 4.4e-06 26.5 8.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFM25009.1 - 8.1e-06 25.6 6.5 1.3e-05 24.9 6.5 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KFM25009.1 - 2.5e-05 24.3 9.8 4.1e-05 23.6 9.8 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 KFM25009.1 - 0.001 19.1 2.1 0.0017 18.4 2.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_IE-1 PF05290.11 KFM25009.1 - 0.0011 18.9 3.9 0.0017 18.3 3.9 1.2 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-rbx1 PF12678.7 KFM25009.1 - 0.0029 17.8 8.0 0.0055 17.0 8.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain U-box PF04564.15 KFM25009.1 - 0.011 15.9 0.0 0.048 13.8 0.0 2.0 2 0 0 2 2 2 0 U-box domain Rtf2 PF04641.12 KFM25009.1 - 0.046 13.1 0.1 0.23 10.8 0.0 1.8 1 1 1 2 2 2 0 Rtf2 RING-finger zf-LITAF-like PF10601.9 KFM25009.1 - 9.1 6.6 12.5 2.7 8.3 7.9 2.2 2 1 0 2 2 2 0 LITAF-like zinc ribbon domain HORMA PF02301.18 KFM25010.1 - 0.0013 18.3 0.0 0.0025 17.4 0.0 1.4 1 1 0 1 1 1 1 HORMA domain Hydrolase_4 PF12146.8 KFM25011.1 - 1.1e-07 31.4 0.1 0.0095 15.2 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFM25011.1 - 0.0005 19.8 0.0 0.045 13.4 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.13 KFM25011.1 - 0.026 14.2 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_4 PF08386.10 KFM25011.1 - 0.047 13.8 0.0 0.078 13.1 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein Peptidase_S9 PF00326.21 KFM25011.1 - 0.19 11.2 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Mcm10 PF09332.11 KFM25012.1 - 2.5e-19 69.9 0.1 3.7e-19 69.4 0.1 1.2 1 0 0 1 1 1 1 Mcm10 replication factor RNA_POL_M_15KD PF02150.16 KFM25012.1 - 0.34 10.8 0.1 0.34 10.8 0.1 2.0 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit HypA PF01155.19 KFM25012.1 - 1.9 8.5 6.6 15 5.6 0.2 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF4379 PF14311.6 KFM25012.1 - 4.7 7.7 10.2 6.7 7.2 6.9 2.5 1 1 1 2 2 2 0 Probable Zinc-ribbon domain SHMT PF00464.19 KFM25013.1 - 8.8e-184 610.7 0.0 1e-183 610.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DegT_DnrJ_EryC1 PF01041.17 KFM25013.1 - 0.12 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KFM25013.1 - 0.14 10.7 0.0 0.21 10.1 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme RTC PF01137.21 KFM25014.1 - 1.9e-50 171.1 0.0 2.2e-50 170.9 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 KFM25014.1 - 1.4e-32 112.3 0.7 2.4e-32 111.5 0.7 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain NUDIX PF00293.28 KFM25015.1 - 1.2e-14 54.5 0.0 2.6e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KFM25015.1 - 3.8e-06 26.9 0.1 7.5e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 NUDIX domain HUN PF08729.10 KFM25015.1 - 0.95 9.5 2.8 0.43 10.6 0.1 1.7 2 0 0 2 2 2 0 HPC2 and ubinuclein domain DEAD PF00270.29 KFM25016.1 - 0.00012 21.9 0.0 0.0002 21.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KFM25016.1 - 0.00023 21.2 0.0 0.00032 20.7 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Knl1_RWD_C PF18210.1 KFM25016.1 - 0.19 12.2 0.0 0.35 11.4 0.0 1.3 1 0 0 1 1 1 0 Knl1 RWD C-terminal domain AAA_23 PF13476.6 KFM25017.1 - 6.8e-29 101.8 0.0 6.8e-29 101.8 0.0 4.0 2 2 1 3 3 2 1 AAA domain SMC_N PF02463.19 KFM25017.1 - 2.8e-13 49.8 0.0 3.3e-12 46.3 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFM25017.1 - 2.1e-11 44.2 0.0 4.7e-05 23.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KFM25017.1 - 1.7e-08 34.6 0.1 0.0041 16.9 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain SbcCD_C PF13558.6 KFM25017.1 - 2e-05 24.7 0.0 0.00019 21.6 0.0 2.8 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 KFM25017.1 - 4.8e-05 23.9 4.0 0.03 14.8 0.0 4.0 3 1 0 3 3 3 2 ABC transporter AAA_29 PF13555.6 KFM25017.1 - 0.0083 15.8 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.6 KFM25017.1 - 0.024 13.3 39.8 0.58 8.7 0.0 6.1 3 1 2 6 6 6 0 AAA domain Rad50_zn_hook PF04423.14 KFM25017.1 - 0.046 13.6 0.7 6.6 6.7 0.0 3.7 2 0 0 2 2 2 0 Rad50 zinc hook motif AAA_22 PF13401.6 KFM25017.1 - 0.074 13.3 2.4 0.33 11.2 0.0 3.5 3 0 0 3 3 3 0 AAA domain FlaC_arch PF05377.11 KFM25017.1 - 0.17 12.3 12.8 20 5.6 0.8 6.9 6 0 0 6 6 6 0 Flagella accessory protein C (FlaC) TSC22 PF01166.18 KFM25017.1 - 0.59 10.5 17.2 17 5.8 0.2 6.1 4 1 2 6 6 6 0 TSC-22/dip/bun family 4HB_MCP_1 PF12729.7 KFM25017.1 - 0.93 9.0 9.1 2.5 7.6 0.4 3.6 3 0 0 3 3 3 0 Four helix bundle sensory module for signal transduction DUF5082 PF16888.5 KFM25017.1 - 1.4 9.2 0.0 1.4 9.2 0.0 6.2 5 2 2 7 7 7 0 Domain of unknown function (DUF5082) DUF1664 PF07889.12 KFM25017.1 - 2.5 8.1 20.4 9.8 6.2 0.4 6.5 5 2 2 7 7 7 0 Protein of unknown function (DUF1664) DUF4298 PF14131.6 KFM25017.1 - 2.6 8.0 4.9 1.2 9.1 0.4 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) YabA PF06156.13 KFM25017.1 - 5.1 7.8 32.4 6.6 7.4 2.5 7.8 6 1 2 8 8 8 0 Initiation control protein YabA FapA PF03961.13 KFM25017.1 - 5.1 5.6 21.1 0.16 10.5 3.0 4.0 2 2 3 5 5 5 0 Flagellar Assembly Protein A DUF3349 PF11829.8 KFM25017.1 - 5.5 7.8 8.4 1.9 9.3 0.0 4.3 4 1 1 5 5 3 0 Protein of unknown function (DUF3349) DUF948 PF06103.11 KFM25017.1 - 8.8 6.7 11.8 11 6.4 0.4 5.6 7 0 0 7 7 5 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 KFM25017.1 - 8.9 6.4 24.5 6.8 6.7 0.5 6.5 6 1 0 7 7 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pkinase_Tyr PF07714.17 KFM25018.1 - 3.9e-52 177.1 0.7 6e-44 150.3 0.1 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KFM25018.1 - 3.4e-41 141.4 0.1 5.5e-40 137.4 0.0 2.0 1 1 1 2 2 2 1 Protein kinase domain Kinase-like PF14531.6 KFM25018.1 - 0.00025 20.5 0.0 0.00038 19.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFM25018.1 - 0.0039 17.1 0.1 0.026 14.5 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFM25018.1 - 0.004 16.2 0.0 0.0059 15.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain DFRP_C PF16543.5 KFM25019.1 - 3.6e-05 24.2 0.0 4.3e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 Prenylcys_lyase PF07156.14 KFM25020.1 - 7.8e-54 183.2 0.0 4.1e-31 108.4 0.0 2.1 1 1 1 2 2 2 2 Prenylcysteine lyase Ank_5 PF13857.6 KFM25021.1 - 4.5e-26 90.6 3.0 8.6e-11 41.9 0.1 4.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM25021.1 - 3.7e-23 81.9 0.1 1.3e-08 35.3 0.2 3.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM25021.1 - 1e-16 61.1 5.3 5.6e-09 36.4 0.1 6.6 3 2 4 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM25021.1 - 1.1e-14 53.1 4.7 0.00027 21.1 0.0 6.4 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 KFM25021.1 - 2e-14 53.3 6.0 4.8e-05 23.6 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat TPR_2 PF07719.17 KFM25022.1 - 7.2e-08 32.0 6.4 0.00019 21.3 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat Methyltransf_25 PF13649.6 KFM25022.1 - 1.6e-07 31.9 0.1 8.6e-07 29.6 0.1 2.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KFM25022.1 - 5.7e-06 25.9 0.0 1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TPR_1 PF00515.28 KFM25022.1 - 9e-06 25.3 3.1 0.012 15.4 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFM25022.1 - 4.4e-05 23.1 1.7 0.00049 19.7 0.5 2.8 2 1 1 3 3 3 1 TPR repeat MTS PF05175.14 KFM25022.1 - 0.0001 21.9 1.6 0.0051 16.4 0.1 2.6 3 0 0 3 3 2 1 Methyltransferase small domain Methyltransf_16 PF10294.9 KFM25022.1 - 0.0033 17.2 0.0 1.5 8.5 0.0 2.3 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 KFM25022.1 - 0.0038 17.1 0.0 0.0079 16.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain TPR_9 PF13371.6 KFM25022.1 - 0.0053 16.9 6.7 0.0087 16.2 5.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat Methyltransf_11 PF08241.12 KFM25022.1 - 0.0073 16.9 0.1 0.026 15.2 0.1 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM25022.1 - 0.011 15.6 0.0 0.028 14.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 KFM25022.1 - 0.042 13.6 0.0 0.071 12.8 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_32 PF13679.6 KFM25022.1 - 0.042 13.8 0.0 0.079 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TPR_17 PF13431.6 KFM25022.1 - 0.052 13.9 1.3 1.9 9.1 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Cons_hypoth95 PF03602.15 KFM25022.1 - 0.069 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_12 PF08242.12 KFM25022.1 - 0.069 13.9 0.0 0.21 12.3 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 KFM25022.1 - 0.14 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase RrnaAD PF00398.20 KFM25022.1 - 0.29 10.2 0.0 0.51 9.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase TPR_19 PF14559.6 KFM25022.1 - 0.91 10.1 7.3 8.9 6.9 1.2 2.8 1 1 2 3 3 3 0 Tetratricopeptide repeat Abhydrolase_1 PF00561.20 KFM25023.1 - 7.3e-17 61.9 0.0 2.6e-12 47.0 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFM25023.1 - 9.4e-17 62.4 0.3 1.5e-16 61.7 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFM25023.1 - 1.6e-10 40.7 0.0 4.4e-10 39.2 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KFM25023.1 - 0.0027 17.8 0.0 0.005 16.9 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Esterase PF00756.20 KFM25023.1 - 0.11 12.1 0.1 0.3 10.7 0.1 1.7 2 0 0 2 2 2 0 Putative esterase Abhydrolase_1 PF00561.20 KFM25024.1 - 2.2e-14 53.7 0.0 2.7e-13 50.1 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFM25024.1 - 1.1e-12 49.1 0.1 1.5e-12 48.6 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFM25024.1 - 4e-11 42.6 0.0 1.1e-10 41.2 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF4033 PF13225.6 KFM25025.1 - 1.6e-23 82.5 0.5 2.5e-23 81.9 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4033) TMEM239 PF15841.5 KFM25026.1 - 0.54 10.1 4.4 2.1 8.2 2.9 2.0 1 1 1 2 2 2 0 Transmembrane protein 239 family DUF3685 PF12452.8 KFM25027.1 - 3.8e-09 36.5 0.0 5.7e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3685) DUF3035 PF11233.8 KFM25027.1 - 0.021 15.1 0.5 0.038 14.3 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3035) His_Phos_1 PF00300.22 KFM25028.1 - 9.4e-26 90.7 0.0 1.5e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) MULE PF10551.9 KFM25030.1 - 0.0014 19.0 0.0 0.0024 18.2 0.0 1.3 1 0 0 1 1 1 1 MULE transposase domain Creatinase_N_2 PF16189.5 KFM25031.1 - 5.4e-29 101.4 0.0 1.4e-28 100.0 0.0 1.7 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Creatinase_N PF01321.18 KFM25031.1 - 8.3e-21 75.0 0.1 1.7e-14 54.6 0.0 2.2 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 KFM25031.1 - 7.4e-12 45.2 1.0 1.3e-11 44.4 0.2 1.8 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 Nramp PF01566.18 KFM25032.1 - 1e-85 287.9 10.7 1e-85 287.9 10.7 1.4 1 1 0 1 1 1 1 Natural resistance-associated macrophage protein Tyr_Deacylase PF02580.16 KFM25033.1 - 1.5e-45 155.3 0.0 2.9e-45 154.3 0.0 1.5 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase zf-CCCH PF00642.24 KFM25033.1 - 0.00058 19.7 0.3 0.00058 19.7 0.3 3.5 4 0 0 4 4 4 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFM25033.1 - 0.0011 19.0 1.0 0.0011 19.0 1.0 3.6 4 0 0 4 4 4 1 Zinc finger domain zf-CCCH_4 PF18044.1 KFM25033.1 - 0.0029 17.3 1.3 0.0029 17.3 1.3 2.5 3 0 0 3 3 3 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KFM25033.1 - 0.081 13.4 16.8 1.1 9.8 1.0 3.6 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger Potassium_chann PF11404.8 KFM25033.1 - 0.57 10.0 0.1 0.57 10.0 0.1 2.0 2 0 0 2 2 2 0 Potassium voltage-gated channel MFS_1 PF07690.16 KFM25034.1 - 4.1e-24 85.2 23.7 4.1e-24 85.2 23.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Tub PF01167.18 KFM25035.1 - 8.5e-35 120.6 0.0 1.6e-33 116.5 0.0 2.1 1 1 0 1 1 1 1 Tub family DUF3527 PF12043.8 KFM25035.1 - 0.15 11.6 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) Arm PF00514.23 KFM25036.1 - 3.4e-18 65.0 48.5 4.3e-06 26.6 0.2 9.0 8 2 1 9 9 9 5 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KFM25036.1 - 6.8e-06 26.5 4.6 5.9e-05 23.5 0.7 9.8 7 3 6 13 13 13 6 HEAT-like repeat HEAT PF02985.22 KFM25036.1 - 0.035 14.3 32.3 0.68 10.4 0.1 8.7 6 1 1 7 7 7 0 HEAT repeat FHA PF00498.26 KFM25037.1 - 9.9e-14 51.5 0.0 1.8e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KFM25037.1 - 3.1e-05 24.2 0.0 0.0001 22.6 0.0 1.9 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Aida_N PF08910.10 KFM25037.1 - 0.00096 19.5 1.8 0.002 18.5 0.9 2.0 1 1 1 2 2 2 1 Aida N-terminus DUF3450 PF11932.8 KFM25037.1 - 0.0075 15.6 3.8 0.0075 15.6 3.8 2.8 3 1 0 3 3 3 1 Protein of unknown function (DUF3450) VGPC1_C PF16799.5 KFM25037.1 - 0.1 12.6 1.6 0.28 11.2 1.6 1.7 1 0 0 1 1 1 0 C-terminal membrane-localisation domain of ion-channel, VCN1 DUF2277 PF10041.9 KFM25037.1 - 1 9.8 6.1 4.9 7.5 0.3 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2277) SANT_DAMP1_like PF16282.5 KFM25038.1 - 7.9e-29 99.7 1.5 1.2e-28 99.1 1.5 1.3 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Myb_DNA-binding PF00249.31 KFM25038.1 - 0.0008 19.5 0.1 0.0026 17.9 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFM25038.1 - 0.0093 16.2 0.0 0.03 14.6 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain DMAP1 PF05499.12 KFM25038.1 - 0.091 12.6 1.8 0.34 10.8 0.0 2.3 2 0 0 2 2 2 0 DNA methyltransferase 1-associated protein 1 (DMAP1) Aldo_ket_red PF00248.21 KFM25039.1 - 7e-69 232.3 0.0 8.7e-69 231.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GIIM PF08388.11 KFM25039.1 - 0.075 13.1 0.0 0.34 11.0 0.0 2.1 2 0 0 2 2 2 0 Group II intron, maturase-specific domain Acetyltransf_1 PF00583.25 KFM25040.1 - 1e-11 45.1 0.0 1.3e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFM25040.1 - 3.8e-07 30.1 0.0 5.5e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFM25040.1 - 1.5e-05 25.3 0.0 2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KFM25040.1 - 0.00079 19.5 0.0 0.0012 18.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFM25040.1 - 0.013 15.4 0.0 0.02 14.9 0.0 1.2 1 0 0 1 1 1 0 FR47-like protein PanZ PF12568.8 KFM25040.1 - 0.027 14.2 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ E1-E2_ATPase PF00122.20 KFM25042.1 - 1.3e-45 155.2 0.2 3.2e-45 153.9 0.2 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KFM25042.1 - 1.5e-33 116.9 1.8 3.5e-33 115.7 1.8 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KFM25042.1 - 1.2e-24 86.5 0.0 1.8e-11 44.3 0.0 3.0 3 0 0 3 3 3 2 Heavy-metal-associated domain HAD PF12710.7 KFM25042.1 - 8.4e-07 29.6 2.8 3.9e-06 27.4 3.1 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KFM25042.1 - 0.001 18.9 2.4 0.0018 18.1 1.8 1.6 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase NifU PF01106.17 KFM25042.1 - 0.35 11.0 1.1 1.7 8.9 0.1 2.2 2 0 0 2 2 2 0 NifU-like domain Fer2_BFD PF04324.15 KFM25042.1 - 0.8 10.1 2.7 8.1 6.9 0.1 2.7 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain DUF2752 PF10825.8 KFM25042.1 - 3.1 7.9 10.0 3.7 7.7 1.7 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2752) Pkinase PF00069.25 KFM25044.1 - 1.4e-37 129.5 0.0 2.1e-37 129.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM25044.1 - 9.6e-32 110.3 0.0 1.5e-31 109.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM25044.1 - 8.7e-05 22.0 0.0 0.00016 21.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFM25044.1 - 0.0011 18.4 0.0 0.0033 16.8 0.0 1.8 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Oxidored_FMN PF00724.20 KFM25045.1 - 9.5e-79 265.1 0.0 1.1e-78 264.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Caf4 PF11615.8 KFM25045.1 - 0.11 12.5 0.1 0.3 11.1 0.1 1.7 2 0 0 2 2 2 0 CCR4-associated factor 4 Acetyltransf_10 PF13673.7 KFM25046.1 - 0.15 12.0 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_L11_N PF03946.14 KFM25046.1 - 0.9 9.4 6.5 0.41 10.5 0.6 3.1 3 0 0 3 3 3 0 Ribosomal protein L11, N-terminal domain VDE PF07137.11 KFM25047.1 - 9.7e-90 300.3 0.0 1.2e-89 300.0 0.0 1.1 1 0 0 1 1 1 1 VDE lipocalin domain Lipocalin PF00061.23 KFM25047.1 - 0.0045 17.2 0.0 0.0088 16.2 0.0 1.5 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family DUF4247 PF14042.6 KFM25047.1 - 0.047 14.4 0.5 0.26 12.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4247) DUF4885 PF16226.5 KFM25047.1 - 0.16 11.0 0.1 0.22 10.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4885) GSHPx PF00255.19 KFM25048.1 - 1.6e-37 127.4 0.0 2.1e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 KFM25048.1 - 4.2e-06 26.7 0.0 7.2e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KFM25048.1 - 0.0086 15.8 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Redoxin MFS_1 PF07690.16 KFM25049.1 - 7.2e-19 67.9 38.3 7.2e-19 67.9 38.3 1.9 2 1 1 3 3 3 2 Major Facilitator Superfamily RIP PF00161.19 KFM25049.1 - 0.0056 16.3 0.2 0.01 15.5 0.2 1.3 1 0 0 1 1 1 1 Ribosome inactivating protein UNC-93 PF05978.16 KFM25049.1 - 0.012 15.3 9.8 0.15 11.8 0.9 2.9 2 1 0 2 2 2 0 Ion channel regulatory protein UNC-93 DUF321 PF03778.13 KFM25049.1 - 0.08 12.6 1.8 1.5 8.6 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF321) Pterin_4a PF01329.19 KFM25051.1 - 1.4e-23 82.8 0.1 1.6e-23 82.7 0.1 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase TFIIS_M PF07500.14 KFM25052.1 - 0.041 14.4 0.0 0.07 13.6 0.0 1.3 1 0 0 1 1 1 0 Transcription factor S-II (TFIIS), central domain DUF3522 PF12036.8 KFM25054.1 - 0.01 16.1 0.7 0.024 14.9 0.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3522) TPR_12 PF13424.6 KFM25055.1 - 6.2e-06 26.4 20.7 0.0096 16.2 5.6 4.2 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFM25055.1 - 2.6e-05 24.0 16.2 0.41 10.9 0.1 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 KFM25055.1 - 0.0014 18.5 22.2 0.058 13.3 0.2 5.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFM25055.1 - 0.0027 17.5 11.2 0.042 13.7 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFM25055.1 - 0.023 14.9 2.6 22 5.6 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFM25055.1 - 0.95 9.6 9.4 0.47 10.6 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat SNAP PF14938.6 KFM25055.1 - 4.1 6.8 7.5 4.2 6.7 0.4 2.5 2 1 1 3 3 3 0 Soluble NSF attachment protein, SNAP Peptidase_C12 PF01088.21 KFM25057.1 - 1.1e-56 191.9 0.0 1.3e-56 191.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DEAD PF00270.29 KFM25058.1 - 1.3e-12 47.8 0.0 2e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase F-box PF00646.33 KFM25058.1 - 0.0013 18.6 1.0 0.0034 17.2 1.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KFM25058.1 - 0.0088 15.9 0.4 0.031 14.2 0.4 2.0 1 0 0 1 1 1 1 F-box-like ResIII PF04851.15 KFM25058.1 - 0.19 11.7 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit EAF PF09816.9 KFM25059.1 - 3e-11 43.6 0.0 4.5e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor SNAP PF14938.6 KFM25060.1 - 5.5e-13 49.0 13.5 1.4e-12 47.6 5.8 2.2 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_2 PF07719.17 KFM25060.1 - 0.026 14.6 0.4 0.026 14.6 0.4 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFM25060.1 - 0.26 11.6 15.3 0.83 10.0 0.4 4.1 2 1 0 3 3 3 0 Tetratricopeptide repeat NSF PF02071.20 KFM25060.1 - 0.51 11.3 8.2 1.1 10.3 0.9 4.7 4 0 0 4 4 4 0 Aromatic-di-Alanine (AdAR) repeat TPR_6 PF13174.6 KFM25060.1 - 0.73 10.6 7.4 0.28 11.9 0.5 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Glyco_hydro_9 PF00759.19 KFM25061.1 - 3.9e-95 319.7 5.8 3.9e-95 319.7 5.8 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 9 SNF2_N PF00176.23 KFM25061.1 - 2.8e-42 144.7 0.6 3e-31 108.4 0.0 2.4 1 1 1 2 2 2 2 SNF2 family N-terminal domain DUF2040 PF09745.9 KFM25061.1 - 3.1e-31 108.0 18.7 3.1e-31 108.0 18.7 2.1 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 55 (DUF2040) Helicase_C PF00271.31 KFM25061.1 - 1.3e-18 67.4 0.0 2.5e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 KFM25061.1 - 5.5e-07 29.4 0.0 0.0088 15.9 0.0 2.6 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 KFM25061.1 - 2.5e-05 24.3 0.0 0.014 15.4 0.0 2.9 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 KFM25061.1 - 0.00018 21.3 0.0 0.00035 20.3 0.0 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase Ribosomal_S6 PF01250.17 KFM25063.1 - 2.4e-12 47.0 0.0 2.7e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 HECT PF00632.25 KFM25064.1 - 1.6e-75 254.4 0.0 2.2e-75 254.0 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Peptidase_M32 PF02074.15 KFM25065.1 - 2e-171 571.1 0.0 2.3e-171 570.9 0.0 1.0 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase adh_short PF00106.25 KFM25066.1 - 5.3e-40 137.0 0.1 7.7e-40 136.4 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM25066.1 - 1.2e-25 90.5 0.4 1.8e-25 89.9 0.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM25066.1 - 6.4e-15 55.5 0.7 9.3e-15 55.0 0.7 1.2 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 KFM25066.1 - 0.068 13.2 0.2 0.3 11.1 0.1 2.1 1 1 1 2 2 2 0 Zinc-binding dehydrogenase THF_DHG_CYH_C PF02882.19 KFM25066.1 - 0.083 12.2 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Amino_oxidase PF01593.24 KFM25067.1 - 4e-92 309.9 2.6 2.2e-91 307.4 2.6 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFM25067.1 - 1.3e-15 57.3 1.0 6.3e-15 55.2 1.0 2.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DEK_C PF08766.11 KFM25067.1 - 9.7e-13 47.8 0.0 2.7e-12 46.4 0.0 1.8 1 0 0 1 1 1 1 DEK C terminal domain SWIRM PF04433.17 KFM25067.1 - 4.1e-08 33.5 0.0 4.3e-07 30.2 0.0 2.6 4 0 0 4 4 2 1 SWIRM domain FAD_binding_3 PF01494.19 KFM25067.1 - 1.3e-07 31.2 0.7 2.5e-07 30.3 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KFM25067.1 - 2.9e-07 29.9 0.5 8.3e-07 28.4 0.5 1.8 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KFM25067.1 - 3.3e-07 29.8 3.1 3.6e-06 26.4 0.9 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFM25067.1 - 3.6e-07 29.2 1.2 1.1e-06 27.7 0.3 2.2 3 0 0 3 3 3 1 HI0933-like protein FAD_oxidored PF12831.7 KFM25067.1 - 3.8e-06 26.5 0.6 8.8e-06 25.3 0.6 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KFM25067.1 - 5.4e-06 25.9 0.1 3.7e-05 23.1 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFM25067.1 - 8.6e-06 25.2 0.4 1.6e-05 24.3 0.4 1.3 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 KFM25067.1 - 2.3e-05 23.8 0.4 4.1e-05 23.0 0.4 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KFM25067.1 - 0.00014 22.4 0.7 0.00056 20.4 0.7 2.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KFM25067.1 - 0.0003 20.0 0.2 0.0003 20.0 0.2 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.22 KFM25067.1 - 0.00032 19.9 0.4 0.00053 19.2 0.4 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Shikimate_DH PF01488.20 KFM25067.1 - 0.0016 18.5 0.2 0.003 17.6 0.2 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 KFM25067.1 - 0.002 17.8 12.0 0.002 17.8 12.0 3.4 1 1 1 2 2 2 1 FAD dependent oxidoreductase Glu_dehyd_C PF16912.5 KFM25067.1 - 0.0048 16.4 0.1 0.009 15.5 0.1 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus NAD_binding_9 PF13454.6 KFM25067.1 - 0.013 15.5 4.6 0.071 13.1 0.5 3.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KFM25067.1 - 0.034 13.0 0.4 0.061 12.2 0.4 1.4 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_7 PF13241.6 KFM25067.1 - 0.22 12.0 1.3 0.45 11.0 0.3 2.0 2 0 0 2 2 1 0 Putative NAD(P)-binding YjeF_N PF03853.15 KFM25067.1 - 0.44 10.4 4.2 0.33 10.8 0.9 2.3 2 0 0 2 2 2 0 YjeF-related protein N-terminus NTF2 PF02136.20 KFM25068.1 - 4.1e-36 124.2 0.2 4.6e-36 124.0 0.2 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RNB PF00773.19 KFM25070.1 - 2.6e-73 247.2 0.0 9.7e-66 222.3 0.0 2.2 1 1 1 2 2 2 2 RNB domain OB_Dis3 PF17849.1 KFM25070.1 - 2.7e-19 68.9 0.0 5.7e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 KFM25070.1 - 3.6e-19 69.4 0.0 8.6e-19 68.1 0.0 1.7 1 0 0 1 1 1 1 PIN domain Rrp44_CSD1 PF17216.3 KFM25070.1 - 2e-11 43.8 0.0 4.1e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 KFM25070.1 - 1.6e-09 37.6 0.0 3.2e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 S1 domain CSD2 PF17876.1 KFM25070.1 - 5.7e-05 23.2 0.0 0.011 15.9 0.0 2.9 3 0 0 3 3 3 1 Cold shock domain Med14 PF08638.11 KFM25071.1 - 1.3e-29 103.0 0.0 2e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 Mediator complex subunit MED14 Ribosomal_S15 PF00312.22 KFM25073.1 - 1.4e-30 105.3 0.5 2.2e-30 104.7 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 Acetyltransf_1 PF00583.25 KFM25073.1 - 3.9e-07 30.3 0.0 1.1e-05 25.6 0.0 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFM25073.1 - 4.9e-07 30.1 0.0 8.9e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFM25073.1 - 0.0024 17.8 0.1 0.045 13.7 0.1 2.6 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KFM25073.1 - 0.0055 16.6 0.0 0.12 12.4 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Paramyxo_PNT PF14320.6 KFM25073.1 - 0.045 12.9 0.1 0.066 12.4 0.1 1.2 1 0 0 1 1 1 0 Phosphoprotein P region PNT disordered MCM PF00493.23 KFM25074.1 - 2.3e-91 304.9 0.0 6.3e-91 303.4 0.0 1.7 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KFM25074.1 - 1.4e-30 105.8 0.0 2.5e-30 104.9 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KFM25074.1 - 7.8e-22 77.5 0.2 1.6e-21 76.5 0.2 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KFM25074.1 - 7.1e-13 49.0 0.0 2e-12 47.6 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KFM25074.1 - 1.3e-08 34.5 0.1 1.6e-06 27.7 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KFM25074.1 - 5.3e-05 23.2 0.0 0.00015 21.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KFM25074.1 - 9e-05 22.3 0.0 0.00047 20.0 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF4148 PF13663.6 KFM25074.1 - 0.00045 20.3 1.8 0.00045 20.3 1.8 2.3 2 0 0 2 2 1 1 Domain of unknown function (DUF4148) Sigma54_activat PF00158.26 KFM25074.1 - 0.0023 17.7 0.1 0.016 14.9 0.1 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.29 KFM25074.1 - 0.0049 17.3 0.0 0.011 16.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFM25074.1 - 0.12 12.8 1.7 0.32 11.4 0.2 2.6 2 1 0 2 2 2 0 AAA ATPase domain AAA_lid_2 PF17863.1 KFM25074.1 - 0.16 11.8 3.5 0.76 9.7 0.1 3.3 3 0 0 3 3 3 0 AAA lid domain adh_short_C2 PF13561.6 KFM25076.1 - 1.6e-45 155.5 6.8 2.7e-43 148.2 6.8 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFM25076.1 - 4e-41 140.6 1.9 5.4e-41 140.2 1.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFM25076.1 - 6.3e-07 29.5 2.7 2e-06 27.8 2.7 1.9 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KFM25076.1 - 0.074 12.9 0.9 0.11 12.3 0.9 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AP-5_subunit_s1 PF15001.6 KFM25077.1 - 9.9 6.1 7.7 6.1 6.8 0.6 2.2 2 0 0 2 2 2 0 AP-5 complex subunit sigma-1 adh_short_C2 PF13561.6 KFM25078.1 - 1.9e-57 194.5 8.3 2.5e-57 194.1 8.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFM25078.1 - 2.4e-53 180.5 8.0 3e-53 180.2 8.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFM25078.1 - 3.1e-15 56.6 4.9 4.5e-15 56.0 4.9 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFM25078.1 - 0.0068 15.9 1.1 0.016 14.7 1.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NMN_transporter PF04973.12 KFM25078.1 - 0.11 12.5 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Nicotinamide mononucleotide transporter NTP_transf_2 PF01909.23 KFM25079.1 - 2.6e-06 27.6 0.0 9e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 Nucleotidyltransferase domain Polbeta PF18765.1 KFM25079.1 - 0.2 11.8 0.0 0.37 10.9 0.0 1.4 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase PAP_assoc PF03828.19 KFM25080.1 - 3.7e-07 30.3 0.0 6.8e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KFM25080.1 - 1.7e-05 25.0 0.0 3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyltransferase domain NIF PF03031.18 KFM25080.1 - 0.00024 20.9 0.0 0.00041 20.2 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Polbeta PF18765.1 KFM25080.1 - 0.24 11.5 0.0 0.46 10.6 0.0 1.4 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase NIF PF03031.18 KFM25081.1 - 4.8e-09 36.2 0.0 0.0017 18.2 0.0 2.1 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase eIF2A PF08662.11 KFM25082.1 - 1.3e-61 207.8 0.0 5e-59 199.4 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 KFM25082.1 - 0.00017 22.3 0.2 9.6 7.3 0.0 4.9 4 1 1 5 5 5 2 WD domain, G-beta repeat PD40 PF07676.12 KFM25082.1 - 0.017 15.1 1.7 5.9 7.0 0.0 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 KFM25082.1 - 0.2 11.4 3.3 12 5.7 0.2 3.3 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature 6PF2K PF01591.18 KFM25083.1 - 9.7e-66 221.3 0.0 1.6e-65 220.5 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KFM25083.1 - 7.1e-33 113.9 0.0 8.3e-32 110.5 0.0 2.1 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) G8 PF10162.9 KFM25083.1 - 6.3e-13 48.9 0.1 1.4e-12 47.7 0.1 1.6 1 0 0 1 1 1 1 G8 domain Beta_helix PF13229.6 KFM25083.1 - 0.017 15.0 8.7 0.1 12.5 5.4 3.2 2 1 1 3 3 3 0 Right handed beta helix region AAA_33 PF13671.6 KFM25083.1 - 0.017 15.3 0.0 0.034 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain HTH_38 PF13936.6 KFM25083.1 - 0.036 13.8 0.0 0.079 12.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain NosD PF05048.13 KFM25083.1 - 0.065 12.5 0.6 0.22 10.7 0.6 1.7 1 1 0 1 1 1 0 Periplasmic copper-binding protein (NosD) S1 PF00575.23 KFM25084.1 - 4.3e-14 52.6 0.3 8.5e-09 35.6 0.1 2.8 2 1 0 2 2 2 2 S1 RNA binding domain DUF2103 PF09876.9 KFM25084.1 - 9.9e-06 25.5 0.1 8.2e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 Predicted metal-binding protein (DUF2103) Transket_pyr PF02779.24 KFM25085.1 - 5.5e-45 153.2 0.0 2.2e-44 151.2 0.0 2.0 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KFM25085.1 - 8.6e-37 125.8 0.1 1.4e-36 125.1 0.1 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 KFM25085.1 - 0.0031 17.8 0.0 0.0074 16.6 0.0 1.7 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II DUF900 PF05990.12 KFM25085.1 - 0.14 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) CAAD PF14159.6 KFM25086.1 - 3.8e-18 65.1 0.0 5.5e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase PseudoU_synth_2 PF00849.22 KFM25087.1 - 4.6e-15 56.1 0.0 8.3e-15 55.2 0.0 1.4 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 KFM25087.1 - 2.2e-09 36.9 0.1 5.7e-09 35.5 0.1 1.8 1 0 0 1 1 1 1 S4 domain Flavoprotein PF02441.19 KFM25088.1 - 1.9e-44 151.2 0.0 2.3e-44 150.9 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein Cmc1 PF08583.10 KFM25089.1 - 1.9e-17 63.0 3.6 2.2e-17 62.8 3.6 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.13 KFM25089.1 - 0.32 11.4 4.6 1.8 8.9 0.7 2.2 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) GCK PF07802.11 KFM25089.1 - 0.49 10.9 3.3 3 8.3 0.7 2.0 1 1 1 2 2 2 0 GCK domain Radical_SAM PF04055.21 KFM25090.1 - 3.4e-21 76.3 0.0 7.1e-12 46.0 0.0 3.3 2 1 0 2 2 2 2 Radical SAM superfamily RCC1 PF00415.18 KFM25091.1 - 1.2e-92 304.4 33.4 1.1e-15 58.0 0.6 8.1 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFM25091.1 - 4.2e-48 160.2 43.8 1e-08 34.8 0.7 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat NHL PF01436.21 KFM25091.1 - 0.56 10.4 1.9 99 3.3 0.0 4.2 5 0 0 5 5 5 0 NHL repeat RNA_pol_Rpb5_C PF01191.19 KFM25092.1 - 1.4e-33 114.6 0.8 2.1e-33 114.0 0.1 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 KFM25092.1 - 2.9e-24 85.5 0.1 6.2e-24 84.4 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 KFM25092.1 - 0.001 19.1 0.0 0.0018 18.3 0.0 1.6 2 0 0 2 2 2 1 Restriction endonuclease NRDE-2 PF08424.10 KFM25094.1 - 1.6e-08 34.0 4.8 0.00025 20.3 0.1 5.0 3 2 2 5 5 5 2 NRDE-2, necessary for RNA interference Suf PF05843.14 KFM25094.1 - 5.9e-07 29.8 0.4 0.079 12.9 0.0 4.4 4 0 0 4 4 4 2 Suppressor of forked protein (Suf) Mad3_BUB1_I PF08311.12 KFM25094.1 - 2.5e-06 27.5 8.3 8.5 6.4 0.1 6.4 6 0 0 6 6 6 3 Mad3/BUB1 homology region 1 TPR_8 PF13181.6 KFM25094.1 - 5.7e-06 26.1 13.8 2.5 8.5 0.1 8.1 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_15 PF13429.6 KFM25094.1 - 0.00011 21.5 16.5 0.038 13.2 0.4 5.8 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFM25094.1 - 0.00019 22.0 51.7 0.96 10.4 0.0 12.0 11 2 2 13 13 11 2 Tetratricopeptide repeat RPN7 PF10602.9 KFM25094.1 - 0.00064 19.5 0.1 0.64 9.7 0.0 3.1 3 0 0 3 3 3 1 26S proteasome subunit RPN7 TPR_2 PF07719.17 KFM25094.1 - 0.00068 19.6 20.3 0.85 9.9 0.1 8.1 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFM25094.1 - 0.0027 18.0 9.3 15 5.9 0.0 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFM25094.1 - 0.018 15.4 2.9 38 5.0 0.1 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat CKAP2_C PF15297.6 KFM25094.1 - 0.02 14.0 0.0 1.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Cytoskeleton-associated protein 2 C-terminus Glyoxalase_6 PF18029.1 KFM25094.1 - 0.073 13.9 6.1 0.16 12.8 3.5 2.9 2 0 0 2 2 2 0 Glyoxalase-like domain PPR PF01535.20 KFM25094.1 - 0.074 13.3 1.1 1.3 9.5 0.0 3.5 3 0 0 3 3 2 0 PPR repeat SNAP PF14938.6 KFM25094.1 - 0.87 9.0 6.9 2.7 7.3 0.9 3.0 3 0 0 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_7 PF13176.6 KFM25094.1 - 0.94 9.7 0.0 0.94 9.7 0.0 6.3 7 0 0 7 7 6 0 Tetratricopeptide repeat Adap_comp_sub PF00928.21 KFM25095.1 - 1.8e-78 263.6 0.0 2.8e-78 262.9 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KFM25095.1 - 9.1e-10 38.6 0.1 1.6e-09 37.8 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Mon1 PF03164.14 KFM25095.1 - 0.043 12.9 0.0 0.062 12.4 0.0 1.1 1 0 0 1 1 1 0 Trafficking protein Mon1 SPT16 PF08644.11 KFM25096.1 - 9.3e-42 142.8 0.3 3.1e-41 141.1 0.0 2.1 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 KFM25096.1 - 1.3e-38 132.4 0.0 4.1e-38 130.7 0.0 1.9 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 KFM25096.1 - 3e-24 85.9 0.3 5.2e-24 85.1 0.3 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 KFM25096.1 - 3.6e-14 52.9 0.4 9e-14 51.7 0.0 1.9 2 0 0 2 2 2 1 Histone chaperone Rttp106-like FtsL PF04999.13 KFM25098.1 - 0.059 13.4 0.3 0.097 12.7 0.3 1.3 1 0 0 1 1 1 0 Cell division protein FtsL AD PF09793.9 KFM25099.1 - 8.6e-15 54.6 0.0 1.4e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain RRM_1 PF00076.22 KFM25100.1 - 7.2e-10 38.5 0.0 1.2e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) VIR_N PF15912.5 KFM25100.1 - 0.1 12.2 2.0 0.15 11.6 2.0 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal PWI PF01480.17 KFM25101.1 - 1.2e-10 41.5 0.2 2.3e-10 40.6 0.2 1.4 1 0 0 1 1 1 1 PWI domain BBIP10 PF14777.6 KFM25101.1 - 0.064 12.8 0.8 0.17 11.5 0.8 1.8 1 1 0 1 1 1 0 Cilia BBSome complex subunit 10 Rtf2 PF04641.12 KFM25101.1 - 0.17 11.2 0.3 0.21 10.9 0.3 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger SAP PF02037.27 KFM25103.1 - 2.8e-07 30.1 1.5 7.5e-07 28.8 1.5 1.8 1 0 0 1 1 1 1 SAP domain PPR PF01535.20 KFM25103.1 - 0.00021 21.3 0.7 0.023 14.9 0.0 3.6 3 0 0 3 3 3 1 PPR repeat PPR_2 PF13041.6 KFM25103.1 - 0.00097 19.3 0.0 0.011 15.9 0.0 2.8 2 2 2 4 4 4 1 PPR repeat family PPR_3 PF13812.6 KFM25103.1 - 0.013 15.6 0.0 0.42 10.7 0.0 3.1 1 1 2 3 3 3 0 Pentatricopeptide repeat domain PPR_long PF17177.4 KFM25103.1 - 0.026 13.9 0.1 0.49 9.7 0.0 2.4 2 0 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP Rib_hydrolayse PF02267.17 KFM25103.1 - 0.046 13.1 0.0 0.081 12.3 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosyl cyclase MA3 PF02847.17 KFM25103.1 - 0.12 12.4 0.7 1.1 9.3 0.1 2.5 1 1 1 2 2 2 0 MA3 domain FAT PF02259.23 KFM25104.1 - 5.3e-78 262.7 0.6 5.3e-78 262.7 0.6 1.8 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 KFM25104.1 - 1.5e-74 251.0 0.0 2.4e-74 250.3 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FRB_dom PF08771.11 KFM25104.1 - 9.4e-42 141.5 3.3 4.9e-41 139.1 1.6 2.8 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain DUF3385 PF11865.8 KFM25104.1 - 1.6e-39 135.4 0.0 6.4e-36 123.7 0.0 3.6 3 1 0 3 3 3 2 Domain of unknown function (DUF3385) FATC PF02260.20 KFM25104.1 - 1.3e-15 56.9 0.9 4.2e-15 55.2 0.9 1.9 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 KFM25104.1 - 5.4e-06 26.2 19.3 1.3 9.4 0.0 10.2 9 0 0 9 9 9 1 HEAT repeat Adaptin_N PF01602.20 KFM25104.1 - 0.0013 17.4 0.0 2.9 6.3 0.0 4.5 4 2 1 5 5 5 1 Adaptin N terminal region TPR_7 PF13176.6 KFM25104.1 - 0.0026 17.7 2.1 0.4 10.8 0.0 4.8 3 0 0 3 3 3 1 Tetratricopeptide repeat HEAT_2 PF13646.6 KFM25104.1 - 0.05 14.0 30.2 0.67 10.4 0.8 9.4 9 1 0 9 9 9 0 HEAT repeats TPR_19 PF14559.6 KFM25104.1 - 0.063 13.8 4.9 8.6 6.9 0.3 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Sec7_N PF12783.7 KFM25104.1 - 0.14 12.1 0.0 4.5 7.2 0.0 3.6 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Cohesin_HEAT PF12765.7 KFM25104.1 - 0.36 11.2 2.1 21 5.5 1.4 3.4 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion TPR_14 PF13428.6 KFM25104.1 - 1.7 9.7 19.7 4.2 8.5 0.0 7.2 7 1 0 7 7 5 0 Tetratricopeptide repeat Tfb2 PF03849.14 KFM25105.1 - 3.9e-70 236.6 0.0 1.1e-53 182.5 0.0 2.5 2 1 1 3 3 3 2 Transcription factor Tfb2 Tfb2_C PF18307.1 KFM25105.1 - 8.5e-13 48.5 0.5 2e-12 47.4 0.5 1.6 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 KFM25105.1 - 0.0022 18.1 0.0 0.0063 16.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Auxin_inducible PF02519.14 KFM25105.1 - 0.038 14.2 0.1 0.08 13.1 0.1 1.5 1 0 0 1 1 1 0 Auxin responsive protein KH_8 PF17903.1 KFM25106.1 - 1.3e-31 108.5 0.0 2.4e-31 107.6 0.0 1.5 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KFM25106.1 - 0.002 17.9 0.0 0.0042 16.9 0.0 1.5 1 0 0 1 1 1 1 KH domain ADK PF00406.22 KFM25107.1 - 8.8e-39 133.0 0.0 1.1e-38 132.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KFM25107.1 - 6.1e-18 65.6 0.3 9.9e-18 64.9 0.0 1.5 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 KFM25107.1 - 0.00087 19.2 1.0 0.002 18.1 0.4 2.0 2 1 0 2 2 2 1 Adenylate kinase, active site lid AAA_33 PF13671.6 KFM25107.1 - 0.0013 19.0 0.0 0.0022 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFM25107.1 - 0.016 15.8 0.0 0.024 15.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Glycos_transf_1 PF00534.20 KFM25108.1 - 1.4e-19 70.3 0.0 2.6e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KFM25108.1 - 3e-10 40.6 0.0 7.4e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Sucrose_synth PF00862.19 KFM25108.1 - 5e-08 31.7 0.0 1.4e-07 30.2 0.0 1.6 1 1 0 1 1 1 1 Sucrose synthase S6PP PF05116.13 KFM25108.1 - 1.3e-05 24.9 0.1 0.024 14.2 0.0 3.3 3 0 0 3 3 3 2 Sucrose-6F-phosphate phosphohydrolase Glyco_trans_1_2 PF13524.6 KFM25108.1 - 3.3e-05 24.2 0.0 9.5e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KFM25108.1 - 0.0051 16.8 1.5 0.014 15.4 0.2 2.4 2 0 0 2 2 2 1 Glycosyltransferase Family 4 DUF1752 PF08550.10 KFM25108.1 - 0.074 12.9 0.2 0.17 11.8 0.2 1.6 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1752) Mito_carr PF00153.27 KFM25109.1 - 1.7e-24 85.5 5.2 9.4e-16 57.5 0.1 4.3 3 2 1 4 4 4 4 Mitochondrial carrier protein LIDHydrolase PF10230.9 KFM25110.1 - 2.5e-17 63.3 0.0 8.4e-10 38.6 0.0 2.0 1 1 1 2 2 2 2 Lipid-droplet associated hydrolase fn3 PF00041.21 KFM25111.1 - 4.5e-79 260.9 0.0 1.3e-09 38.2 0.0 10.6 9 4 0 9 9 9 9 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFM25111.1 - 2.6e-14 53.5 0.0 2.5 8.7 0.0 8.3 9 1 0 9 9 9 5 Purple acid Phosphatase, N-terminal domain PhoD_N PF16655.5 KFM25111.1 - 0.075 13.6 0.0 46 4.7 0.0 3.6 3 0 0 3 3 3 0 PhoD-like phosphatase, N-terminal domain DUF2237 PF09996.9 KFM25111.1 - 0.1 12.6 0.0 0.45 10.5 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2237) GatB_N PF02934.15 KFM25112.1 - 4.4e-109 364.1 0.0 5.5e-109 363.8 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 KFM25112.1 - 3.1e-39 134.2 0.0 1.2e-38 132.3 0.0 1.9 1 1 0 1 1 1 1 GatB domain TRAPPC-Trs85 PF12739.7 KFM25113.1 - 3.6e-41 141.5 3.5 1.2e-19 70.5 0.0 4.1 1 1 3 4 4 4 4 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TPR_4 PF07721.14 KFM25113.1 - 5.2 8.0 20.3 0.86 10.4 0.5 5.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Gpr1_Fun34_YaaH PF01184.19 KFM25115.1 - 8.2e-17 61.5 16.6 1.3e-16 60.8 16.6 1.3 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family SNF2_N PF00176.23 KFM25116.1 - 1.1e-61 208.5 0.0 1.6e-61 208.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFM25116.1 - 3.9e-20 72.2 0.0 9.4e-20 71.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM25116.1 - 0.00027 21.0 0.0 0.00065 19.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KFM25116.1 - 0.0022 17.2 0.0 0.007 15.6 0.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 GILT PF03227.16 KFM25117.1 - 7.3e-19 68.0 0.0 9.8e-19 67.6 0.0 1.1 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Thioredoxin_4 PF13462.6 KFM25117.1 - 0.022 14.9 0.1 0.026 14.7 0.1 1.3 1 1 0 1 1 1 0 Thioredoxin UbiA PF01040.18 KFM25118.1 - 4.9e-33 114.5 29.6 6.6e-33 114.1 29.6 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF832 PF05734.11 KFM25119.1 - 0.18 11.3 2.6 0.15 11.5 2.6 1.1 1 0 0 1 1 1 0 Herpesvirus protein of unknown function (DUF832) Peptidase_S8 PF00082.22 KFM25120.1 - 1.3e-33 116.6 8.4 2e-33 116.0 8.4 1.2 1 0 0 1 1 1 1 Subtilase family F5_F8_type_C PF00754.25 KFM25120.1 - 6.7e-09 35.9 0.0 1.5e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 F5/8 type C domain Peptidase_S8_N PF16361.5 KFM25120.1 - 0.15 12.6 0.3 0.66 10.5 0.2 2.1 1 1 1 2 2 2 0 N-terminal of Subtilase family PPTA PF01239.22 KFM25121.1 - 3.7e-39 131.3 12.4 4.1e-10 39.0 0.6 5.9 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat Phenyl_P_gamma PF09662.10 KFM25121.1 - 0.14 12.3 0.0 12 6.1 0.0 2.3 2 0 0 2 2 2 0 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) Actin PF00022.19 KFM25122.1 - 1.8e-122 408.9 0.0 2e-122 408.7 0.0 1.0 1 0 0 1 1 1 1 Actin Ribosomal_L7Ae PF01248.26 KFM25123.1 - 1.4e-25 88.8 0.2 1.7e-25 88.6 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 KFM25123.1 - 6.5e-05 22.7 0.1 8.4e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain Linker_histone PF00538.19 KFM25123.1 - 0.0086 16.4 0.8 0.28 11.6 0.0 2.1 2 0 0 2 2 2 1 linker histone H1 and H5 family YadA_stalk PF05662.14 KFM25123.1 - 0.44 11.0 4.6 1.5 9.2 0.4 2.5 2 0 0 2 2 2 0 Coiled stalk of trimeric autotransporter adhesin adh_short PF00106.25 KFM25124.1 - 1.5e-21 76.8 0.0 2.6e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM25124.1 - 3.1e-16 59.7 0.0 3.9e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM25124.1 - 7.9e-07 29.2 0.1 1.3e-06 28.5 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KFM25124.1 - 1.8e-05 24.7 0.1 2.8e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Proteasome PF00227.26 KFM25126.1 - 1.7e-41 141.8 0.3 2.1e-41 141.5 0.3 1.0 1 0 0 1 1 1 1 Proteasome subunit zf-C2H2_jaz PF12171.8 KFM25127.1 - 6e-08 32.8 3.5 6.1e-06 26.4 0.3 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KFM25127.1 - 3.1e-05 24.2 4.3 0.023 15.2 0.6 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.7 KFM25127.1 - 0.00021 21.5 1.4 0.031 14.7 0.1 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KFM25127.1 - 0.0011 19.6 10.7 0.036 14.9 0.3 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger DUF1391 PF07151.12 KFM25127.1 - 0.084 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1391) PyrI_C PF02748.15 KFM25127.1 - 0.11 12.5 0.4 0.11 12.5 0.4 2.2 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_6 PF13912.6 KFM25127.1 - 0.13 12.3 0.8 0.13 12.3 0.8 2.7 2 1 1 3 3 3 0 C2H2-type zinc finger DUF2310 PF10071.9 KFM25127.1 - 0.45 9.7 2.7 0.59 9.4 2.7 1.2 1 0 0 1 1 1 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) HypA PF01155.19 KFM25127.1 - 0.77 9.8 6.3 0.095 12.7 1.4 1.8 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA eIF-3_zeta PF05091.12 KFM25129.1 - 5.8e-115 385.2 0.0 1.5e-67 228.8 0.0 3.8 1 1 3 4 4 4 4 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) AMP-binding PF00501.28 KFM25130.1 - 3.6e-89 299.3 0.8 6.2e-88 295.2 0.8 2.0 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFM25130.1 - 0.00012 23.0 1.0 0.00056 20.8 0.0 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 KFM25131.1 - 1.6e-101 339.9 0.0 2.9e-101 339.1 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFM25131.1 - 2.4e-06 28.4 0.1 2.4e-06 28.4 0.1 2.4 2 1 1 3 3 3 1 AMP-binding enzyme C-terminal domain His_Phos_1 PF00300.22 KFM25132.1 - 2.1e-42 145.0 2.0 6.5e-41 140.2 1.0 2.4 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) P-II PF00543.22 KFM25135.1 - 1.3e-22 80.3 2.9 1.5e-22 80.1 2.9 1.1 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II ThiF PF00899.21 KFM25136.1 - 4.7e-101 337.2 0.0 1.3e-69 234.3 0.0 2.4 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 KFM25136.1 - 2.8e-74 250.2 0.6 4.3e-74 249.6 0.6 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 KFM25136.1 - 1e-25 90.2 0.0 2.1e-25 89.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 KFM25136.1 - 1.5e-21 76.3 0.1 4.3e-21 74.9 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle E1_FCCH PF16190.5 KFM25136.1 - 7.5e-19 67.7 0.0 1.4e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain UPF0020 PF01170.18 KFM25137.1 - 1.4e-13 51.0 0.0 3.8e-12 46.3 0.0 2.4 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 KFM25137.1 - 3.8e-05 23.5 0.0 0.00098 18.9 0.0 2.1 2 0 0 2 2 2 1 DNA methylase Cons_hypoth95 PF03602.15 KFM25137.1 - 0.0017 18.0 0.0 0.0066 16.1 0.0 1.8 1 1 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 KFM25137.1 - 0.011 16.3 0.0 0.33 11.6 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain MethyltransfD12 PF02086.15 KFM25137.1 - 0.025 14.3 0.1 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase N6_Mtase PF02384.16 KFM25137.1 - 0.29 10.3 0.0 2 7.6 0.0 1.9 2 0 0 2 2 2 0 N-6 DNA Methylase Pro_CA PF00484.19 KFM25138.1 - 3.6e-49 167.0 0.2 4.8e-49 166.6 0.2 1.2 1 0 0 1 1 1 1 Carbonic anhydrase TRAM_LAG1_CLN8 PF03798.16 KFM25138.1 - 9.2e-10 38.6 8.8 1.8e-09 37.6 8.8 1.4 1 0 0 1 1 1 1 TLC domain DNA_mis_repair PF01119.19 KFM25139.1 - 2.1e-25 88.7 0.0 3.7e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain Mlh1_C PF16413.5 KFM25139.1 - 4.6e-24 85.2 0.1 3.9e-11 42.8 0.0 2.2 1 1 1 2 2 2 2 DNA mismatch repair protein Mlh1 C-terminus HATPase_c_3 PF13589.6 KFM25139.1 - 1e-07 31.9 0.1 2.8e-07 30.5 0.1 1.7 1 1 1 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KFM25139.1 - 0.018 15.5 0.0 0.04 14.4 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PCI PF01399.27 KFM25140.1 - 2.6e-12 47.2 0.4 5.8e-12 46.1 0.1 1.8 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.17 KFM25140.1 - 0.6 10.4 3.0 3.6 7.9 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Nramp PF01566.18 KFM25141.1 - 5.6e-99 331.5 26.0 5.6e-99 331.5 26.0 1.7 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein MBOAT PF03062.19 KFM25141.1 - 1.6e-16 60.6 13.1 2.1e-09 37.2 0.2 3.3 4 0 0 4 4 4 2 MBOAT, membrane-bound O-acyltransferase family Nramp PF01566.18 KFM25142.1 - 5.1e-94 315.2 28.2 8.3e-94 314.5 28.2 1.3 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Pex19 PF04614.12 KFM25142.1 - 1.8e-31 109.8 0.0 2.4e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 Pex19 protein family DED PF01335.21 KFM25142.1 - 0.12 12.7 0.2 0.34 11.2 0.2 1.7 2 0 0 2 2 2 0 Death effector domain TCR PF03638.15 KFM25143.1 - 1.3e-22 79.8 42.9 6.5e-12 45.6 20.0 2.2 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain adh_short PF00106.25 KFM25144.1 - 6.7e-19 68.1 0.0 1.7e-17 63.5 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM25144.1 - 4.1e-09 36.4 0.0 9e-09 35.2 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM25144.1 - 2.7e-06 27.4 0.0 4.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KFM25144.1 - 0.082 12.8 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Imm31 PF15591.6 KFM25144.1 - 0.13 12.1 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 31 UPRTase PF14681.6 KFM25145.1 - 4.6e-19 68.7 0.0 4.9e-19 68.6 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase UPRTase PF14681.6 KFM25146.1 - 1.7e-33 115.9 0.0 2e-33 115.6 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase p450 PF00067.22 KFM25148.1 - 4.5e-15 55.3 0.1 2.1e-12 46.6 0.0 3.1 1 1 1 2 2 2 1 Cytochrome P450 ETC_C1_NDUFA5 PF04716.14 KFM25148.1 - 0.016 15.0 0.0 9.5 6.1 0.0 2.4 2 0 0 2 2 2 0 ETC complex I subunit conserved region DNA_ligase_IV PF11411.8 KFM25148.1 - 0.023 14.8 2.2 6.2 7.0 0.2 2.5 2 0 0 2 2 2 0 DNA ligase IV LysR_substrate PF03466.20 KFM25148.1 - 0.071 12.5 6.2 3.4 7.0 0.6 3.5 3 1 0 3 3 3 0 LysR substrate binding domain FA_FANCE PF11510.8 KFM25148.1 - 0.074 12.4 0.1 14 5.0 0.0 2.2 2 0 0 2 2 2 0 Fanconi Anaemia group E protein FANCE DUF5389 PF17364.2 KFM25148.1 - 0.12 12.4 2.1 72 3.5 0.1 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5389) Methyltransf_PK PF05891.12 KFM25149.1 - 4.8e-52 176.6 0.0 1.1e-50 172.2 0.0 2.1 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 KFM25149.1 - 2.5e-09 37.7 0.0 5e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFM25149.1 - 2.4e-06 28.1 0.0 4.4e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM25149.1 - 0.00064 19.6 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM25149.1 - 0.00066 20.4 0.0 0.0017 19.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain bZIP_Maf PF03131.17 KFM25149.1 - 0.079 13.5 2.6 0.18 12.3 2.6 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_1 PF00170.21 KFM25149.1 - 0.11 12.6 7.3 0.19 11.9 7.3 1.3 1 0 0 1 1 1 0 bZIP transcription factor Methyltransf_2 PF00891.18 KFM25149.1 - 0.13 11.5 0.0 0.26 10.6 0.0 1.4 1 1 0 1 1 1 0 O-methyltransferase domain SNARE_assoc PF09335.11 KFM25150.1 - 8.2e-26 90.9 6.0 1.7e-25 89.8 6.0 1.6 1 0 0 1 1 1 1 SNARE associated Golgi protein Aa_trans PF01490.18 KFM25150.1 - 0.0033 16.2 0.0 0.0057 15.4 0.0 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Glyco_transf_92 PF01697.27 KFM25151.1 - 1.2e-07 31.7 0.0 2e-07 30.9 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 KFM25151.1 - 3.2e-06 27.5 0.0 6.4e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 DHDPS PF00701.22 KFM25154.1 - 8.2e-82 274.2 0.0 9.3e-82 274.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Ribonuc_red_sm PF00268.21 KFM25157.1 - 1.9e-117 391.7 0.1 2.2e-117 391.5 0.1 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Ran-binding PF05508.11 KFM25159.1 - 4.7e-17 62.0 0.0 2.2e-09 36.7 0.4 2.1 1 1 1 2 2 2 2 RanGTP-binding protein Abhydrolase_1 PF00561.20 KFM25160.1 - 9.9e-07 28.6 0.4 6e-06 26.1 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Thioesterase PF00975.20 KFM25160.1 - 0.045 13.9 0.2 0.27 11.3 0.1 2.2 2 0 0 2 2 2 0 Thioesterase domain Dak2 PF02734.17 KFM25161.1 - 2.3e-09 37.4 0.3 3.3e-06 27.1 0.0 2.0 1 1 1 2 2 2 2 DAK2 domain Dak1 PF02733.17 KFM25162.1 - 7.3e-79 264.9 7.1 1.2e-59 201.7 7.1 2.0 1 1 1 2 2 2 2 Dak1 domain HMG_box PF00505.19 KFM25163.1 - 1.1e-06 29.0 0.1 1.5e-06 28.5 0.1 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFM25163.1 - 0.00059 20.4 0.1 0.00078 20.0 0.1 1.2 1 0 0 1 1 1 1 HMG-box domain EntA_Immun PF08951.10 KFM25164.1 - 0.0044 17.3 0.7 0.007 16.7 0.7 1.2 1 0 0 1 1 1 1 Enterocin A Immunity DUF2390 PF09523.10 KFM25164.1 - 0.015 15.6 1.6 0.018 15.4 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2390) Spc7 PF08317.11 KFM25164.1 - 0.029 13.3 1.0 0.038 12.9 1.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein LMP PF04778.12 KFM25164.1 - 0.037 13.9 0.1 0.051 13.5 0.1 1.1 1 0 0 1 1 1 0 LMP repeated region APG17 PF04108.12 KFM25164.1 - 0.067 12.3 0.4 0.09 11.9 0.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 S_4TM PF18159.1 KFM25164.1 - 1.3 8.2 4.1 0.56 9.5 1.3 1.7 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain NAD_binding_10 PF13460.6 KFM25165.1 - 0.0033 17.3 0.6 0.04 13.8 0.1 2.1 1 1 2 3 3 3 1 NAD(P)H-binding DEAD PF00270.29 KFM25167.1 - 6.3e-40 136.8 0.0 1.1e-39 136.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM25167.1 - 4.1e-23 81.8 0.0 1e-22 80.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KFM25167.1 - 7.9e-18 64.4 0.0 1.9e-17 63.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) AAA_22 PF13401.6 KFM25167.1 - 0.001 19.3 1.7 0.31 11.3 0.3 3.2 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 KFM25167.1 - 0.034 14.1 0.0 0.066 13.2 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Chloroa_b-bind PF00504.21 KFM25168.1 - 2e-47 161.7 0.0 2.5e-47 161.4 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Complex1_LYR_2 PF13233.6 KFM25169.1 - 1.2e-13 51.6 0.3 1.8e-13 51.0 0.3 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KFM25169.1 - 3.3e-08 33.4 0.2 4.9e-08 32.9 0.2 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Tom22 PF04281.13 KFM25169.1 - 5.8e-06 26.1 0.1 9.9e-06 25.4 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Complex1_LYR_1 PF13232.6 KFM25169.1 - 0.056 14.0 0.2 0.093 13.3 0.2 1.3 1 0 0 1 1 1 0 Complex1_LYR-like DUF3253 PF11625.8 KFM25169.1 - 0.21 11.8 1.2 0.53 10.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3253) Branch PF02485.21 KFM25174.1 - 5.4e-39 134.2 0.0 7.3e-39 133.7 0.0 1.1 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Peptidase_S24 PF00717.23 KFM25175.1 - 3.7e-07 30.0 0.1 6.8e-07 29.2 0.1 1.4 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 KFM25175.1 - 8.4e-06 25.6 0.1 0.00021 21.1 0.1 2.4 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 GidB PF02527.15 KFM25176.1 - 5.9e-26 90.9 0.0 2.2e-20 72.8 0.0 2.1 1 1 1 2 2 2 2 rRNA small subunit methyltransferase G zf-Tim10_DDP PF02953.15 KFM25177.1 - 1.5e-14 53.4 3.8 1.6e-14 53.3 3.8 1.0 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Pkinase_Tyr PF07714.17 KFM25179.1 - 2e-40 138.7 0.0 2.3e-35 122.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KFM25179.1 - 3.4e-31 108.6 0.0 1.1e-30 106.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 KFM25179.1 - 0.0018 18.3 1.6 0.0047 16.9 0.1 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFM25179.1 - 0.016 14.2 0.1 0.028 13.4 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain URO-D PF01208.17 KFM25180.1 - 1.9e-107 359.4 0.0 2.2e-107 359.2 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) NAD_binding_10 PF13460.6 KFM25181.1 - 1e-40 139.6 0.1 1.4e-40 139.1 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KFM25181.1 - 2.3e-15 56.8 0.0 2.9e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KFM25181.1 - 2.8e-11 43.4 0.1 6.2e-11 42.2 0.1 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFM25181.1 - 4.9e-10 38.9 0.1 6.8e-10 38.4 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 KFM25181.1 - 1.3e-05 25.4 0.6 2.3e-05 24.6 0.1 1.6 2 0 0 2 2 2 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 KFM25181.1 - 2.7e-05 24.4 0.3 6e-05 23.3 0.3 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain RmlD_sub_bind PF04321.17 KFM25181.1 - 5.9e-05 22.3 0.6 0.0078 15.3 0.6 2.6 2 1 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KFM25181.1 - 6.6e-05 22.2 0.2 0.00012 21.3 0.2 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KFM25181.1 - 0.00011 21.7 2.3 0.00016 21.2 0.7 1.9 2 0 0 2 2 2 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 KFM25181.1 - 0.00067 19.1 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 KFM25181.1 - 0.0059 16.7 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase adh_short_C2 PF13561.6 KFM25181.1 - 0.016 14.7 1.0 0.062 12.8 0.4 2.0 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase ApbA PF02558.16 KFM25181.1 - 0.017 14.8 0.2 0.029 14.0 0.2 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HIM1 PF08732.10 KFM25181.1 - 0.02 14.4 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 HIM1 Ldh_1_N PF00056.23 KFM25181.1 - 0.03 14.4 0.5 0.075 13.1 0.5 1.7 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain DapB_N PF01113.20 KFM25181.1 - 0.035 14.2 0.1 0.064 13.4 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus KR PF08659.10 KFM25181.1 - 0.036 14.0 1.5 0.47 10.4 0.8 2.4 3 0 0 3 3 3 0 KR domain NAD_binding_7 PF13241.6 KFM25181.1 - 0.14 12.6 0.1 0.39 11.2 0.1 1.6 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_synthase PF02540.17 KFM25181.1 - 0.43 9.6 2.7 1.2 8.2 0.5 2.0 2 0 0 2 2 2 0 NAD synthase Methyltransf_11 PF08241.12 KFM25182.1 - 4.1e-18 65.8 0.0 7.3e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM25182.1 - 1.3e-15 57.8 0.0 2.2e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KFM25182.1 - 1.5e-13 50.7 0.0 2.3e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 KFM25182.1 - 1.2e-10 41.4 0.0 1.7e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM25182.1 - 2.2e-10 40.6 0.0 3e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM25182.1 - 6.9e-09 36.4 0.0 1.1e-08 35.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KFM25182.1 - 1.9e-05 24.1 0.0 2.7e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Ubie_methyltran PF01209.18 KFM25182.1 - 6.5e-05 22.4 0.0 0.00012 21.5 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 KFM25182.1 - 0.0035 16.0 0.0 0.0044 15.6 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.14 KFM25182.1 - 0.027 14.0 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain GMC_oxred_N PF00732.19 KFM25183.1 - 9.5e-44 149.9 1.9 1.8e-43 149.0 1.9 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFM25183.1 - 3.1e-23 82.9 0.5 2.5e-22 80.0 0.5 2.2 1 1 0 1 1 1 1 GMC oxidoreductase Putative_PNPOx PF01243.20 KFM25183.1 - 0.018 15.2 0.0 0.063 13.5 0.0 1.9 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase Mannosyl_trans PF05007.13 KFM25185.1 - 3.8e-63 213.8 4.1 5.5e-63 213.2 4.1 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) GT87 PF09594.10 KFM25185.1 - 3.1e-12 46.7 27.8 3.1e-12 46.7 27.8 2.8 2 1 2 4 4 4 1 Glycosyltransferase family 87 PIG-U PF06728.13 KFM25185.1 - 1.6e-10 40.6 0.1 1.6e-10 40.6 0.1 2.0 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U Pkinase PF00069.25 KFM25186.1 - 3.5e-66 223.3 0.0 4.3e-66 223.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM25186.1 - 1e-28 100.4 0.0 1.3e-28 100.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFM25186.1 - 0.001 18.1 0.0 0.002 17.1 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFM25186.1 - 0.0013 18.1 0.0 0.014 14.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KFM25186.1 - 0.0027 17.7 0.7 0.0093 15.9 0.4 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KFM25186.1 - 0.049 13.0 0.0 0.078 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KFM25186.1 - 0.091 11.8 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 TRAM_LAG1_CLN8 PF03798.16 KFM25187.1 - 6.7e-07 29.2 15.8 1e-06 28.6 15.5 1.4 1 1 0 1 1 1 1 TLC domain Peripla_BP_2 PF01497.18 KFM25188.1 - 1.8e-09 37.5 0.0 3e-08 33.5 0.0 2.1 2 0 0 2 2 2 2 Periplasmic binding protein Mon2_C PF16206.5 KFM25189.1 - 8e-32 110.3 0.0 1.4e-28 99.5 0.0 2.4 2 0 0 2 2 2 2 C-terminal region of Mon2 protein DCB PF16213.5 KFM25189.1 - 3.2e-26 92.1 0.2 7.6e-26 90.8 0.2 1.6 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 DUF1981 PF09324.10 KFM25189.1 - 7e-06 25.8 0.0 0.00013 21.8 0.0 3.1 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) Sec7_N PF12783.7 KFM25189.1 - 0.00013 21.9 0.0 0.00049 20.0 0.0 2.0 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Bac_surface_Ag PF01103.23 KFM25192.1 - 2.8e-12 46.8 0.0 3.8e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Surface antigen Glu-tRNAGln PF02686.15 KFM25194.1 - 4.1e-13 49.4 0.1 5.5e-13 49.0 0.1 1.2 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit DUF4101 PF13355.6 KFM25195.1 - 1.7e-14 54.2 1.6 2.2e-12 47.4 0.1 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF4101) PsbP PF01789.16 KFM25196.1 - 4e-05 23.8 1.4 0.24 11.5 0.3 2.2 1 1 1 2 2 2 2 PsbP ALO PF04030.14 KFM25197.1 - 1.1e-06 28.6 0.0 1.9e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 KFM25197.1 - 0.0054 16.5 0.4 0.015 15.0 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain Pro_isomerase PF00160.21 KFM25198.1 - 7.5e-50 169.3 0.0 9.2e-50 169.0 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TIP120 PF08623.10 KFM25199.1 - 8.5e-43 146.0 0.0 7.1e-42 143.0 0.0 2.6 2 1 1 3 3 3 1 TATA-binding protein interacting (TIP20) Cnd1 PF12717.7 KFM25199.1 - 8.6e-08 32.4 1.4 0.3 11.1 0.0 6.0 6 1 0 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Laminin_G_3 PF13385.6 KFM25199.1 - 0.00013 22.1 0.0 0.00027 21.1 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Adaptin_N PF01602.20 KFM25199.1 - 0.0004 19.1 1.4 0.12 10.9 0.2 4.1 4 1 1 5 5 5 1 Adaptin N terminal region fn2 PF00040.19 KFM25199.1 - 0.0015 18.8 0.3 1.1 9.6 0.0 2.8 2 0 0 2 2 2 2 Fibronectin type II domain Vac14_Fab1_bd PF12755.7 KFM25199.1 - 0.008 16.7 0.0 0.11 13.0 0.0 3.1 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region TFCD_C PF12612.8 KFM25199.1 - 0.016 15.0 1.6 40 4.0 0.0 4.7 5 0 0 5 5 5 0 Tubulin folding cofactor D C terminal BID PF06393.11 KFM25199.1 - 0.037 13.6 0.1 0.14 11.7 0.1 2.0 1 0 0 1 1 1 0 BH3 interacting domain (BID) Cohesin_HEAT PF12765.7 KFM25199.1 - 0.076 13.3 0.8 31 5.0 0.0 3.7 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 KFM25199.1 - 8.6 6.9 41.1 1.2 9.6 0.0 10.1 10 0 0 10 10 10 0 HEAT repeat Aldedh PF00171.22 KFM25200.1 - 2.8e-150 500.8 0.0 2.4e-96 323.1 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family Ank_4 PF13637.6 KFM25201.1 - 7e-23 80.7 0.1 1e-12 48.3 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM25201.1 - 5e-22 78.3 2.6 1.8e-15 57.2 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFM25201.1 - 8.7e-16 57.8 0.1 3.8e-09 36.6 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KFM25201.1 - 2.4e-13 49.9 0.2 1.1e-05 25.6 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat STI1 PF17830.1 KFM25201.1 - 3.2e-13 49.4 16.8 2.3e-06 27.4 0.0 5.8 4 2 0 5 5 5 3 STI1 domain Ank_3 PF13606.6 KFM25201.1 - 2e-12 46.1 0.1 5.1e-05 23.4 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat GerD PF17898.1 KFM25201.1 - 8.8e-05 22.4 9.5 0.054 13.5 0.5 3.2 2 1 1 3 3 3 2 Spore germination GerD central core domain Nif11 PF07862.11 KFM25201.1 - 0.018 15.3 0.7 0.56 10.5 0.0 3.2 3 1 0 3 3 3 0 Nif11 domain XPC-binding PF09280.11 KFM25201.1 - 0.12 12.2 0.3 0.12 12.2 0.3 3.0 4 0 0 4 4 4 0 XPC-binding domain AAA_5 PF07728.14 KFM25202.1 - 4.7e-24 84.9 0.0 8.4e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_8 PF17868.1 KFM25202.1 - 7.3e-19 67.4 0.0 1.5e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 AAA lid domain AAA_3 PF07726.11 KFM25202.1 - 6.4e-05 22.8 0.0 0.00013 21.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KFM25202.1 - 0.00045 19.7 0.0 0.0018 17.7 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA PF00004.29 KFM25202.1 - 0.0053 17.2 0.0 0.017 15.5 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFM25202.1 - 0.096 13.1 4.7 0.086 13.2 1.9 2.5 2 1 0 2 2 2 0 AAA ATPase domain TFIIIC_delta PF12657.7 KFM25203.1 - 4.5e-10 39.8 0.1 9.2e-10 38.7 0.1 1.4 1 1 0 1 1 1 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 KFM25203.1 - 0.14 12.1 0.4 0.27 11.2 0.4 1.3 1 0 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex Histone PF00125.24 KFM25204.1 - 1e-16 61.5 0.3 1.3e-16 61.1 0.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFM25204.1 - 0.0041 17.4 0.1 0.0092 16.2 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone_H2A_C PF16211.5 KFM25205.1 - 1.1e-19 69.9 1.3 1.9e-19 69.1 1.3 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KFM25205.1 - 5e-15 56.0 0.0 6e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFM25205.1 - 1.6e-05 25.1 0.0 2.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KFM25206.1 - 2e-18 66.6 0.0 2.3e-18 66.4 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit DUF3437 PF11919.8 KFM25207.1 - 2.5e-19 69.0 2.8 4.8e-19 68.1 0.0 3.1 4 0 0 4 4 4 1 Domain of unknown function (DUF3437) BLM10_mid PF16507.5 KFM25207.1 - 6.5e-18 64.7 0.0 8.5e-07 28.0 0.0 3.2 3 0 0 3 3 3 3 Proteasome-substrate-size regulator, mid region HEAT PF02985.22 KFM25207.1 - 0.13 12.6 2.3 1.8 9.0 0.1 3.8 3 0 0 3 3 3 0 HEAT repeat Linker_histone PF00538.19 KFM25208.1 - 8.7e-11 42.0 0.0 8.7e-11 42.0 0.0 4.1 3 1 1 4 4 4 2 linker histone H1 and H5 family Apolipoprotein PF01442.18 KFM25208.1 - 4e-06 26.8 12.9 0.00025 21.0 11.7 2.1 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 KFM25208.1 - 4.5e-05 23.6 28.0 0.0065 16.6 11.5 2.6 1 1 1 2 2 2 2 Apolipophorin-III precursor (apoLp-III) HTH_Crp_2 PF13545.6 KFM25208.1 - 0.092 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Phasin PF05597.11 KFM25208.1 - 0.13 12.3 20.1 3.7 7.6 4.3 4.1 1 1 3 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) HD_4 PF13328.6 KFM25209.1 - 2.4e-61 206.0 10.7 1e-28 100.1 4.6 3.7 2 2 1 3 3 3 3 HD domain RelA_SpoT PF04607.17 KFM25209.1 - 4.3e-34 117.3 0.0 1.2e-14 54.6 0.0 3.3 3 0 0 3 3 3 3 Region found in RelA / SpoT proteins TGS PF02824.21 KFM25209.1 - 1e-23 83.2 0.0 9.5e-20 70.4 0.0 2.6 2 0 0 2 2 2 2 TGS domain HD PF01966.22 KFM25209.1 - 6.7e-08 32.8 5.4 0.0012 19.0 1.2 4.0 2 2 0 2 2 2 2 HD domain ACT PF01842.25 KFM25209.1 - 7.5e-06 25.6 0.0 2.9e-05 23.7 0.0 2.0 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 KFM25209.1 - 0.00027 21.5 0.0 0.00076 20.0 0.0 1.7 1 0 0 1 1 1 1 ACT domain Bclt PF15318.6 KFM25209.1 - 0.056 13.3 0.5 11 5.8 0.1 2.8 2 0 0 2 2 2 0 Putative Bcl-2 like protein of testis Oxysterol_BP PF01237.18 KFM25210.1 - 5.1e-07 28.9 0.0 1.8e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 Oxysterol-binding protein CNF1 PF05785.12 KFM25211.1 - 0.07 12.4 0.1 0.085 12.1 0.1 1.1 1 0 0 1 1 1 0 Rho-activating domain of cytotoxic necrotizing factor Thioesterase PF00975.20 KFM25212.1 - 4.8e-24 85.8 0.0 5.8e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 KFM25212.1 - 1.6e-12 48.5 8.1 2.1e-12 48.1 8.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KFM25212.1 - 0.0076 16.1 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFM25212.1 - 0.01 15.1 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFM25212.1 - 0.042 13.5 0.0 2.9 7.4 0.0 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold LIDHydrolase PF10230.9 KFM25212.1 - 0.048 13.2 0.0 0.063 12.8 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Gly_transf_sug PF04488.15 KFM25216.1 - 1.8e-08 34.9 0.0 2.9e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif MTS PF05175.14 KFM25216.1 - 0.0036 16.9 0.0 0.0077 15.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 KFM25216.1 - 0.0043 16.8 0.0 0.0064 16.3 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_23 PF13489.6 KFM25216.1 - 0.0064 16.3 0.0 0.017 14.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM25216.1 - 0.012 16.3 0.0 0.062 14.0 0.0 2.2 3 0 0 3 3 3 0 Methyltransferase domain Cons_hypoth95 PF03602.15 KFM25216.1 - 0.033 13.8 0.0 0.052 13.2 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_32 PF13679.6 KFM25216.1 - 0.083 12.9 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KFM25216.1 - 0.12 13.0 0.0 0.34 11.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain KfrA_N PF11740.8 KFM25216.1 - 0.13 13.0 0.2 0.13 13.0 0.2 2.6 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term PrmA PF06325.13 KFM25216.1 - 0.21 10.9 0.0 0.32 10.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) ABC2_membrane PF01061.24 KFM25217.1 - 1.5e-29 103.0 20.6 1.5e-29 103.0 20.6 1.5 2 0 0 2 2 1 1 ABC-2 type transporter ABC_tran PF00005.27 KFM25217.1 - 2.2e-24 86.5 0.0 3.3e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KFM25217.1 - 5.6e-07 29.7 0.0 0.012 15.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 KFM25217.1 - 0.00045 19.4 18.1 0.00068 18.8 18.1 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_29 PF13555.6 KFM25217.1 - 0.00055 19.6 0.1 0.0015 18.2 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFM25217.1 - 0.0013 18.6 0.3 0.0025 17.7 0.3 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_18 PF13238.6 KFM25217.1 - 0.0059 17.2 0.0 0.0098 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFM25217.1 - 0.0067 16.8 0.1 0.013 15.8 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 KFM25217.1 - 0.022 14.4 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KFM25217.1 - 0.047 14.0 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KFM25217.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KFM25217.1 - 0.17 12.4 0.0 0.28 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KFM25217.1 - 0.17 12.1 0.1 0.32 11.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KFM25217.1 - 0.18 11.6 0.1 0.31 10.8 0.1 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF2427 PF10348.9 KFM25217.1 - 0.36 10.6 7.9 8.2 6.3 0.1 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF2427) UPF0016 PF01169.19 KFM25220.1 - 4.6e-44 148.6 16.9 3.1e-22 78.7 3.9 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Mntp PF02659.15 KFM25220.1 - 0.026 14.3 9.6 1.1 9.1 6.9 2.7 1 1 1 2 2 2 0 Putative manganese efflux pump Fungal_trans_2 PF11951.8 KFM25222.1 - 0.21 10.4 0.0 0.3 9.8 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Carboxyl_trans PF01039.22 KFM25223.1 - 5.6e-147 490.3 0.0 7e-147 490.0 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 KFM25223.1 - 3.8e-05 23.3 1.2 0.13 11.8 0.1 2.2 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) LRR_6 PF13516.6 KFM25224.1 - 9.5e-05 22.2 0.7 0.011 15.8 0.6 2.8 2 0 0 2 2 2 2 Leucine Rich repeat SLAC1 PF03595.17 KFM25226.1 - 1.6e-39 136.1 53.4 1.8e-39 135.9 53.4 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel MttA_Hcf106 PF02416.16 KFM25227.1 - 3.5e-08 32.6 0.9 5.5e-08 32.0 0.9 1.3 1 0 0 1 1 1 1 mttA/Hcf106 family Thioredoxin PF00085.20 KFM25228.1 - 2.5e-11 43.5 0.0 3.2e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Aa_trans PF01490.18 KFM25230.1 - 6.5e-41 140.4 6.6 8.3e-41 140.0 6.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 KFM25231.1 - 8.4e-29 100.5 18.3 9.8e-29 100.3 18.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KFM25231.1 - 2e-06 27.1 12.0 2e-06 27.1 10.7 1.6 1 1 1 2 2 2 1 Tryptophan/tyrosine permease family DUF2499 PF10693.9 KFM25232.1 - 1.3e-25 89.4 1.6 1.5e-25 89.3 1.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2499) Cpn10 PF00166.21 KFM25233.1 - 1.3e-17 63.6 0.0 1.5e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit E1_FCCH PF16190.5 KFM25233.1 - 0.16 12.2 0.0 0.27 11.5 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-activating enzyme E1 FCCH domain GTP_EFTU PF00009.27 KFM25235.1 - 5.2e-24 84.9 0.0 8.3e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KFM25235.1 - 3.9e-18 65.5 0.0 8.8e-18 64.4 0.0 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 DUF4224 PF13986.6 KFM25235.1 - 0.00059 19.7 2.5 4.6 7.2 0.0 3.6 3 0 0 3 3 3 2 Domain of unknown function (DUF4224) GTP_EFTU_D2 PF03144.25 KFM25235.1 - 0.012 15.9 0.4 1.9 8.9 0.1 2.7 2 0 0 2 2 2 0 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFM25235.1 - 0.013 15.5 0.0 0.032 14.3 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Hydrolase PF00702.26 KFM25235.1 - 0.016 15.5 0.3 0.037 14.3 0.3 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase RsgA_GTPase PF03193.16 KFM25235.1 - 0.16 11.9 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase Prefoldin PF02996.17 KFM25236.1 - 1.4e-17 63.7 0.1 1.7e-17 63.4 0.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF3209 PF11483.8 KFM25236.1 - 0.2 12.2 0.3 1.2 9.6 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3209) DBR1 PF05011.13 KFM25237.1 - 2.8e-27 95.8 0.0 4.6e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 KFM25237.1 - 1.7e-08 35.2 0.1 2.3e-08 34.8 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFM25237.1 - 0.048 13.8 0.0 0.094 12.9 0.0 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Aminotran_1_2 PF00155.21 KFM25238.1 - 3.3e-35 121.9 0.0 4.1e-35 121.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KFM25238.1 - 0.16 11.2 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Aa_trans PF01490.18 KFM25239.1 - 1.5e-79 267.6 33.5 1.7e-79 267.5 33.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KFM25239.1 - 3.3e-06 26.4 13.0 3.3e-06 26.4 13.0 2.9 1 1 2 3 3 3 1 Tryptophan/tyrosine permease family Pkinase_Tyr PF07714.17 KFM25241.1 - 4.7e-39 134.2 0.0 4.1e-32 111.5 0.0 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KFM25241.1 - 2.5e-37 128.7 0.0 7.7e-29 100.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 KFM25241.1 - 0.014 14.7 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFM25241.1 - 0.037 13.6 0.0 0.07 12.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Sugar_tr PF00083.24 KFM25244.1 - 7.4e-30 104.2 16.0 8.4e-17 61.2 3.3 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter DMT_YdcZ PF04657.13 KFM25244.1 - 0.33 11.2 13.4 2.8 8.2 0.7 3.9 3 1 0 3 3 3 0 Putative inner membrane exporter, YdcZ Glyco_hydro_18 PF00704.28 KFM25245.1 - 2.2e-09 37.5 0.0 2.6e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Sugar_tr PF00083.24 KFM25246.1 - 1.2e-30 106.8 14.1 1.6e-15 56.9 4.2 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KFM25246.1 - 3.2e-17 62.5 25.4 3.2e-17 62.5 25.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5336 PF17270.2 KFM25246.1 - 0.29 10.8 2.2 0.6 9.7 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5336) MCM_OB PF17207.3 KFM25247.1 - 4.5e-10 39.5 0.1 7.8e-10 38.7 0.1 1.3 1 0 0 1 1 1 1 MCM OB domain Peptidase_S9_N PF02897.15 KFM25248.1 - 9.5e-80 268.4 0.0 1.1e-65 222.1 0.0 2.1 1 1 1 2 2 2 2 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 KFM25248.1 - 1.2e-62 211.1 0.0 1.8e-62 210.6 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Pkinase_Tyr PF07714.17 KFM25249.1 - 1.5e-24 86.7 0.0 3.1e-24 85.7 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KFM25249.1 - 8.1e-20 71.3 0.0 1.3e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RRM_1 PF00076.22 KFM25249.1 - 2.1e-07 30.7 0.0 3.5e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GAF PF01590.26 KFM25249.1 - 1.1e-06 29.3 0.0 3.2e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 GAF domain DUF966 PF06136.13 KFM25253.1 - 0.013 15.3 1.0 0.014 15.1 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Flu_B_NS1 PF02942.14 KFM25253.1 - 0.36 9.9 0.9 0.55 9.3 0.9 1.2 1 0 0 1 1 1 0 Influenza B non-structural protein (NS1) RR_TM4-6 PF06459.12 KFM25253.1 - 1 9.1 4.8 1.3 8.8 4.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CENP-H PF05837.12 KFM25253.1 - 3.5 8.1 10.9 5.3 7.5 10.9 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) eIF3_subunit PF08597.10 KFM25253.1 - 3.9 7.3 12.2 4.7 7.0 12.2 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF3138 PF11336.8 KFM25253.1 - 8.5 4.9 8.2 11 4.5 8.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF4554 PF15091.6 KFM25253.1 - 9.8 4.9 9.6 13 4.5 9.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Transposase_31 PF04754.12 KFM25254.1 - 0.099 12.2 0.0 0.11 12.1 0.0 1.0 1 0 0 1 1 1 0 Putative transposase, YhgA-like DUF155 PF02582.14 KFM25255.1 - 1.4e-20 74.1 0.2 1.2e-19 71.0 0.2 2.1 1 1 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 ABA_GPCR PF12430.8 KFM25257.1 - 9.4e-21 74.4 0.0 1.4e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 KFM25257.1 - 7.6e-16 58.0 0.0 1.8e-15 56.7 0.0 1.7 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal LMBR1 PF04791.16 KFM25257.1 - 0.044 12.7 0.0 0.056 12.3 0.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Palm_thioest PF02089.15 KFM25258.1 - 5.4e-73 245.8 0.0 6.3e-73 245.6 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 KFM25258.1 - 0.00057 19.4 0.0 0.00067 19.2 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_2 PF01674.18 KFM25258.1 - 0.22 11.0 0.0 1.1 8.8 0.0 2.0 2 0 0 2 2 2 0 Lipase (class 2) Abhydrolase_6 PF12697.7 KFM25258.1 - 0.34 11.5 4.9 0.52 10.9 4.9 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Methyltransf_25 PF13649.6 KFM25259.1 - 1.1e-08 35.6 0.0 2.6e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KFM25259.1 - 9.1e-07 28.5 0.0 1.2e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KFM25259.1 - 2.9e-06 27.0 0.0 6.4e-06 25.8 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_11 PF08241.12 KFM25259.1 - 4e-06 27.4 0.0 9.2e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM25259.1 - 0.0002 22.0 0.0 0.00038 21.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM25259.1 - 0.00021 21.2 0.0 0.00068 19.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 KFM25259.1 - 0.0004 20.3 0.0 0.0006 19.7 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_31 PF13847.6 KFM25259.1 - 0.00043 20.1 0.0 0.00071 19.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 KFM25259.1 - 0.001 18.9 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein CMAS PF02353.20 KFM25259.1 - 0.0019 17.6 0.0 0.003 16.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_24 PF13578.6 KFM25259.1 - 0.0082 17.2 0.0 0.02 15.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KFM25259.1 - 0.0092 15.6 0.1 0.015 15.0 0.1 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_9 PF08003.11 KFM25259.1 - 0.023 13.6 0.0 0.032 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) TehB PF03848.14 KFM25259.1 - 0.064 12.6 0.0 0.097 12.1 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB YL1 PF05764.13 KFM25260.1 - 4.6e-14 53.1 21.6 3.2e-08 34.0 2.1 2.1 1 1 1 2 2 2 2 YL1 nuclear protein YL1_C PF08265.11 KFM25260.1 - 2.2e-10 40.1 0.0 3.5e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Flu_M1_C PF08289.11 KFM25260.1 - 0.054 13.7 0.2 0.094 12.9 0.2 1.4 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain PI3_PI4_kinase PF00454.27 KFM25262.1 - 3.8e-35 121.9 0.0 6.1e-35 121.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 KFM25262.1 - 4.9e-12 45.4 2.5 6.8e-12 45.0 0.5 2.3 2 0 0 2 2 2 1 FATC domain FAT PF02259.23 KFM25262.1 - 9.4e-09 34.9 0.0 0.00013 21.3 0.0 2.3 1 1 1 2 2 2 2 FAT domain TPR_14 PF13428.6 KFM25262.1 - 2.1 9.4 0.0 2.1 9.4 0.0 8.8 7 1 0 7 7 7 0 Tetratricopeptide repeat DUF3223 PF11523.8 KFM25263.1 - 4.9e-17 62.5 0.0 9.2e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3223) WD40 PF00400.32 KFM25263.1 - 5.3e-06 27.1 0.1 0.15 13.0 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM25263.1 - 0.0016 18.7 0.0 0.0067 16.7 0.0 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain GTP_EFTU PF00009.27 KFM25265.1 - 4.1e-61 205.9 0.0 6e-61 205.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KFM25265.1 - 2.9e-30 104.6 0.0 7e-30 103.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 KFM25265.1 - 1.9e-21 75.9 0.0 4.3e-21 74.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 KFM25265.1 - 7.7e-15 54.8 0.0 2e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KFM25265.1 - 1.6e-12 47.6 0.0 4.4e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 SHS2_Rpb7-N PF03876.17 KFM25265.1 - 0.00038 20.8 0.1 0.0066 16.8 0.0 2.9 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RPA43_OB PF17875.1 KFM25265.1 - 0.0019 18.8 1.1 0.0099 16.5 0.0 2.4 2 1 1 3 3 3 1 RPA43 OB domain in RNA Pol I MMR_HSR1 PF01926.23 KFM25265.1 - 0.016 15.3 0.1 0.046 13.8 0.1 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AP2 PF00847.20 KFM25266.1 - 0.00056 20.1 0.2 0.001 19.2 0.2 1.5 1 0 0 1 1 1 1 AP2 domain Clat_adaptor_s PF01217.20 KFM25267.1 - 2.8e-52 176.4 0.5 3e-52 176.4 0.5 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain stn_TNFRSF12A PF12191.8 KFM25268.1 - 0.00035 20.8 0.1 0.00072 19.8 0.1 1.5 1 0 0 1 1 1 1 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain 2Fe-2S_Ferredox PF11591.8 KFM25268.1 - 0.048 13.5 0.5 0.11 12.4 0.5 1.6 1 0 0 1 1 1 0 Ferredoxin chloroplastic transit peptide Ribo_biogen_C PF04034.13 KFM25270.1 - 3.2e-44 149.7 0.0 4e-44 149.4 0.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 KFM25270.1 - 1e-08 34.8 0.0 2.2e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Aa_trans PF01490.18 KFM25271.1 - 2.4e-52 178.1 31.4 8.1e-31 107.1 13.7 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Aa_trans PF01490.18 KFM25272.1 - 8e-73 245.5 23.0 9.4e-73 245.2 23.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 KFM25273.1 - 5.1e-34 117.7 0.0 8e-33 113.7 0.0 2.2 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Pentapeptide_2 PF01469.18 KFM25274.1 - 6e-08 32.5 17.7 1.1e-07 31.6 17.7 1.3 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Mito_fiss_reg PF05308.11 KFM25274.1 - 6 6.9 13.6 12 5.9 13.6 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator Pyridoxal_deC PF00282.19 KFM25275.1 - 4.6e-15 55.2 0.0 2.2e-14 53.0 0.0 2.0 2 1 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KFM25275.1 - 0.00012 21.2 0.0 0.00026 20.1 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V DUF3455 PF11937.8 KFM25276.1 - 3.3e-05 24.3 0.0 7.2e-05 23.2 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3455) PsbP PF01789.16 KFM25277.1 - 1.1e-43 149.0 0.3 1.4e-43 148.8 0.3 1.0 1 0 0 1 1 1 1 PsbP Pkinase PF00069.25 KFM25278.1 - 1.6e-69 234.2 0.0 1.9e-69 233.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM25278.1 - 6.3e-30 104.3 0.0 1.5e-29 103.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM25278.1 - 0.0037 16.6 0.0 0.011 15.1 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 KFM25278.1 - 0.026 13.9 0.1 0.051 12.9 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFM25278.1 - 0.039 13.9 1.9 0.1 12.5 0.0 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 KFM25278.1 - 0.16 11.6 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 LRR_6 PF13516.6 KFM25279.1 - 0.023 14.7 0.2 2.1 8.6 0.2 4.0 5 0 0 5 5 5 0 Leucine Rich repeat UCH PF00443.29 KFM25280.1 - 4.3e-17 62.4 0.0 6e-12 45.6 0.0 2.0 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFM25280.1 - 0.3 10.6 0.0 23 4.5 0.1 2.2 2 1 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase DEAD PF00270.29 KFM25282.1 - 2.1e-39 135.1 0.0 4.4e-39 134.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM25282.1 - 4.2e-30 104.3 0.0 8.8e-29 100.1 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM25282.1 - 1.8e-06 28.0 0.0 3.4e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KFM25282.1 - 0.0066 15.8 0.3 0.38 10.1 0.0 2.3 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.6 KFM25282.1 - 0.021 15.2 0.1 0.2 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KFM25282.1 - 0.049 13.9 0.1 0.18 12.1 0.1 2.0 1 1 0 1 1 1 0 AAA domain tRNA-synt_1b PF00579.25 KFM25282.1 - 0.086 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) AAA_30 PF13604.6 KFM25282.1 - 0.14 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Branch PF02485.21 KFM25283.1 - 7.7e-39 133.7 0.0 2e-38 132.3 0.0 1.7 1 1 0 1 1 1 1 Core-2/I-Branching enzyme TFIID-18kDa PF02269.16 KFM25283.1 - 6.9e-20 70.9 0.0 1.6e-19 69.7 0.0 1.6 1 1 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit DUF4559 PF15112.6 KFM25283.1 - 0.19 11.4 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) GED PF02212.18 KFM25284.1 - 4.3e-10 39.6 0.1 9.5e-10 38.5 0.1 1.5 2 0 0 2 2 2 1 Dynamin GTPase effector domain Dynamin_M PF01031.20 KFM25284.1 - 8e-07 28.6 0.0 1.1e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Dynamin central region PH PF00169.29 KFM25284.1 - 2.5e-06 28.0 0.0 4e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 PH domain Aph-1 PF06105.12 KFM25285.1 - 1.7e-09 37.4 11.3 2e-09 37.2 11.3 1.0 1 0 0 1 1 1 1 Aph-1 protein Peptidase_M48_N PF16491.5 KFM25286.1 - 2.2e-47 161.3 0.0 3.3e-47 160.7 0.0 1.3 1 0 0 1 1 1 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 KFM25286.1 - 4.3e-41 140.8 0.0 7.2e-41 140.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M78 PF06114.13 KFM25286.1 - 0.15 12.0 0.2 4.2 7.3 0.1 3.1 4 0 0 4 4 4 0 IrrE N-terminal-like domain Brix PF04427.18 KFM25287.1 - 5.1e-30 105.0 0.0 6.9e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 Brix domain VEFS-Box PF09733.9 KFM25288.1 - 5.1e-17 62.0 1.3 9.4e-17 61.1 1.3 1.3 1 0 0 1 1 1 1 VEFS-Box of polycomb protein DUF4720 PF15846.5 KFM25288.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4720) Glyco_hydro_31 PF01055.26 KFM25289.1 - 2.5e-137 458.7 0.1 3.3e-137 458.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KFM25289.1 - 3.5e-19 69.1 0.0 5.7e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Trefoil PF00088.18 KFM25289.1 - 1.8e-10 40.6 8.8 1.8e-10 40.6 8.8 2.1 2 0 0 2 2 2 1 Trefoil (P-type) domain Gal_mutarotas_2 PF13802.6 KFM25289.1 - 0.00012 22.3 0.0 0.00038 20.7 0.0 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like Aldedh PF00171.22 KFM25291.1 - 4.9e-120 401.2 3.3 3.2e-90 302.9 2.6 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family LuxC PF05893.14 KFM25291.1 - 0.012 14.7 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) PrpR_N PF06506.11 KFM25291.1 - 0.016 14.8 0.1 0.047 13.3 0.0 1.8 2 0 0 2 2 2 0 Propionate catabolism activator ENTH PF01417.20 KFM25292.1 - 1.5e-35 122.0 0.0 2.1e-35 121.5 0.0 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KFM25292.1 - 0.0026 16.8 0.0 0.0033 16.4 0.0 1.1 1 0 0 1 1 1 1 ANTH domain VHS PF00790.19 KFM25292.1 - 0.079 12.8 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 VHS domain WD40 PF00400.32 KFM25293.1 - 1.1 10.2 6.5 1.2 10.2 0.7 3.7 4 0 0 4 4 4 0 WD domain, G-beta repeat Neurochondrin PF05536.11 KFM25295.1 - 6.1e-33 114.1 0.0 7.1e-25 87.4 0.0 2.2 2 0 0 2 2 2 2 Neurochondrin Myb_DNA-binding PF00249.31 KFM25296.1 - 4.2e-24 84.5 1.5 4e-13 49.3 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFM25296.1 - 2.5e-17 62.9 1.0 2.5e-10 40.5 0.1 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain ATP-synt_F PF01990.17 KFM25297.1 - 1.6e-28 98.9 0.0 1.8e-28 98.7 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit UDPGP PF01704.18 KFM25298.1 - 6.6e-07 28.3 0.0 6.9e-06 25.0 0.0 2.0 1 1 1 2 2 2 2 UTP--glucose-1-phosphate uridylyltransferase FBPase PF00316.20 KFM25299.1 - 9.8e-57 191.5 0.4 1.3e-56 191.0 0.4 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain BK_channel_a PF03493.18 KFM25300.1 - 3.1e-16 59.3 0.0 6.7e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 KFM25300.1 - 1.2e-11 44.4 5.5 3.8e-11 42.8 5.5 1.8 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 KFM25300.1 - 4.6e-11 42.4 11.6 8.5e-11 41.6 11.6 1.3 1 0 0 1 1 1 1 Ion transport protein TrkA_N PF02254.18 KFM25300.1 - 0.0025 18.0 0.1 1.3 9.3 0.0 3.3 2 1 1 3 3 3 1 TrkA-N domain ATP_bind_1 PF03029.17 KFM25301.1 - 1.8e-71 240.7 0.0 2.1e-71 240.5 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CbiA PF01656.23 KFM25301.1 - 2.3e-06 27.7 0.0 3.1e-06 27.3 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 KFM25301.1 - 9.3e-06 24.8 0.0 1.5e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CLP1_P PF16575.5 KFM25301.1 - 1.7e-05 24.7 0.0 3.3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_33 PF13671.6 KFM25301.1 - 5.2e-05 23.4 0.0 7.4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFM25301.1 - 0.00012 22.6 0.0 0.00029 21.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_31 PF13614.6 KFM25301.1 - 0.00014 21.8 0.0 0.011 15.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFM25301.1 - 0.00022 21.0 0.0 0.00036 20.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 KFM25301.1 - 0.00047 19.7 0.0 0.00063 19.3 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 SRP54 PF00448.22 KFM25301.1 - 0.0006 19.5 0.0 0.00091 18.9 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain ArsA_ATPase PF02374.15 KFM25301.1 - 0.00075 18.8 0.0 0.0011 18.2 0.0 1.2 1 0 0 1 1 1 1 Anion-transporting ATPase MipZ PF09140.11 KFM25301.1 - 0.00078 18.8 0.0 0.0015 17.9 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ AAA_17 PF13207.6 KFM25301.1 - 0.0015 19.0 0.0 0.0033 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFM25301.1 - 0.0026 18.2 0.0 0.0045 17.4 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFM25301.1 - 0.0037 17.5 0.0 0.0062 16.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KFM25301.1 - 0.0048 17.3 0.0 0.0075 16.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KFM25301.1 - 0.0054 17.1 0.0 0.0092 16.4 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_25 PF13481.6 KFM25301.1 - 0.0058 16.2 0.0 0.016 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KFM25301.1 - 0.0088 16.1 0.0 0.033 14.3 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 KFM25301.1 - 0.014 15.6 0.0 0.023 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KFM25301.1 - 0.017 14.9 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_5 PF07728.14 KFM25301.1 - 0.023 14.7 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 KFM25301.1 - 0.027 14.4 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 NTPase ParA PF10609.9 KFM25301.1 - 0.04 13.4 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 KFM25301.1 - 0.043 13.3 0.0 0.88 9.0 0.0 2.4 3 0 0 3 3 2 0 Cellulose biosynthesis protein BcsQ Sigma54_activ_2 PF14532.6 KFM25301.1 - 0.046 13.8 0.2 1.5 8.9 0.1 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 KFM25301.1 - 0.051 12.9 0.0 0.086 12.1 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Fer4_NifH PF00142.18 KFM25301.1 - 0.053 13.0 0.0 0.077 12.4 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ABC_tran PF00005.27 KFM25301.1 - 0.065 13.8 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Thymidylate_kin PF02223.17 KFM25301.1 - 0.075 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase AAA_14 PF13173.6 KFM25301.1 - 0.094 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KFM25301.1 - 0.12 12.1 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase cobW PF02492.19 KFM25301.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.6 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain APS_kinase PF01583.20 KFM25301.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase NACHT PF05729.12 KFM25301.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Glyco_trans_4_4 PF13579.6 KFM25301.1 - 0.14 12.6 0.7 0.2 12.1 0.7 1.5 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain AAA_29 PF13555.6 KFM25301.1 - 0.17 11.7 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KFM25301.1 - 0.2 11.2 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region ADK PF00406.22 KFM25301.1 - 0.2 11.7 0.0 0.45 10.6 0.0 1.6 1 0 0 1 1 1 0 Adenylate kinase Cytidylate_kin PF02224.18 KFM25301.1 - 0.22 11.2 0.0 0.37 10.5 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase Aldo_ket_red PF00248.21 KFM25302.1 - 6.6e-50 170.0 0.0 1.1e-47 162.6 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Pullulanase_Ins PF18494.1 KFM25302.1 - 0.016 15.7 0.0 0.031 14.8 0.0 1.4 1 0 0 1 1 1 0 Pullulanase Ins domain NUDIX PF00293.28 KFM25303.1 - 1.3e-11 44.7 0.0 2.3e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 KFM25303.1 - 1.7e-08 35.0 0.6 3.5e-08 34.0 0.6 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 KFM25303.1 - 1.6e-06 27.7 5.7 3e-06 26.8 5.7 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain DNA_ligase_ZBD PF03119.16 KFM25303.1 - 0.058 13.4 1.4 0.15 12.1 1.4 1.7 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain zf-ribbon_3 PF13248.6 KFM25303.1 - 0.18 11.3 0.1 0.31 10.5 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Thioredoxin PF00085.20 KFM25304.1 - 2.3e-14 53.2 0.0 2.8e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 KFM25304.1 - 0.002 18.1 0.0 0.0024 17.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_3 PF13192.6 KFM25304.1 - 0.0057 16.7 0.0 0.0075 16.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_2 PF13098.6 KFM25304.1 - 0.0071 16.8 0.1 0.049 14.1 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KFM25304.1 - 0.0077 16.4 0.2 0.015 15.5 0.2 1.5 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 KFM25304.1 - 0.0098 15.7 0.0 0.012 15.4 0.0 1.2 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_4 PF13462.6 KFM25304.1 - 0.04 14.1 0.2 4.4 7.4 0.1 2.1 1 1 1 2 2 2 0 Thioredoxin Thioredoxin_8 PF13905.6 KFM25304.1 - 0.047 14.0 0.1 0.095 13.0 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like TraF PF13728.6 KFM25304.1 - 0.066 13.0 0.1 0.78 9.5 0.1 2.0 1 1 0 1 1 1 0 F plasmid transfer operon protein Gaa1 PF04114.14 KFM25305.1 - 1.2e-10 41.1 0.0 2.7e-10 39.9 0.0 1.4 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component zf-CSL PF05207.13 KFM25306.1 - 2.4e-20 72.0 1.6 2.9e-20 71.7 1.6 1.1 1 0 0 1 1 1 1 CSL zinc finger zf-RING_7 PF02591.15 KFM25306.1 - 0.046 13.9 0.1 0.11 12.8 0.1 1.6 1 0 0 1 1 1 0 C4-type zinc ribbon domain Metallophos_C PF14008.6 KFM25307.1 - 1.2e-12 48.5 0.3 3.8e-12 46.9 0.1 2.0 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.28 KFM25307.1 - 4.3e-09 37.2 0.2 2e-08 35.0 0.2 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase UQ_con PF00179.26 KFM25308.1 - 2.8e-40 137.2 0.0 4e-40 136.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Methyltransf_28 PF02636.17 KFM25308.1 - 5.3e-35 121.3 0.0 1.6e-16 60.7 0.0 3.2 1 1 2 3 3 3 3 Putative S-adenosyl-L-methionine-dependent methyltransferase UBA PF00627.31 KFM25308.1 - 3.1e-07 30.2 1.0 3.1e-07 30.2 1.0 1.8 2 0 0 2 2 2 1 UBA/TS-N domain Prok-E2_B PF14461.6 KFM25308.1 - 0.00078 19.2 0.0 0.0013 18.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B LETM1 PF07766.13 KFM25310.1 - 9.7e-99 330.0 0.1 1.7e-98 329.2 0.1 1.4 1 0 0 1 1 1 1 LETM1-like protein EF-hand_8 PF13833.6 KFM25310.1 - 2.1e-05 24.3 0.0 0.00011 22.0 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 KFM25310.1 - 7.9e-05 22.0 0.2 0.00032 20.1 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.32 KFM25310.1 - 0.0004 19.7 0.1 0.0082 15.6 0.0 3.1 4 0 0 4 4 4 1 EF hand EF-hand_6 PF13405.6 KFM25310.1 - 0.0021 17.8 0.2 0.045 13.7 0.0 3.1 4 0 0 4 4 4 1 EF-hand domain EF-hand_7 PF13499.6 KFM25310.1 - 0.0068 16.8 0.3 0.052 14.0 0.3 2.6 1 1 0 1 1 1 1 EF-hand domain pair Htr2 PF17909.1 KFM25310.1 - 2.7 8.3 8.3 7.6 6.9 8.3 1.7 1 0 0 1 1 1 0 Htr2 transmembrane domain FmiP_Thoc5 PF09766.9 KFM25311.1 - 1.8e-36 126.2 0.3 5.1e-34 118.1 0.0 2.5 2 1 1 3 3 3 2 Fms-interacting protein/Thoc5 TPR_MLP1_2 PF07926.12 KFM25311.1 - 0.47 10.5 7.8 2.2 8.4 0.2 2.6 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein AhpC-TSA PF00578.21 KFM25312.1 - 1e-12 48.0 0.0 1.4e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KFM25312.1 - 3.5e-08 33.3 0.0 5e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin SURF6 PF04935.12 KFM25313.1 - 1.7e-22 80.2 54.8 1.7e-21 76.9 48.5 3.1 2 1 0 2 2 2 2 Surfeit locus protein 6 RRP14 PF15459.6 KFM25313.1 - 1.1e-14 54.7 1.0 1.1e-14 54.7 1.0 5.3 3 2 0 3 3 3 1 60S ribosome biogenesis protein Rrp14 MMR_HSR1 PF01926.23 KFM25314.1 - 1.3e-21 76.8 0.0 1.9e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFM25314.1 - 3.9e-09 36.2 0.0 5.1e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KFM25314.1 - 1.2e-07 31.8 0.0 0.00013 21.9 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 KFM25314.1 - 6.2e-05 22.5 0.0 9.8e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 KFM25314.1 - 0.00013 22.0 0.1 0.014 15.5 0.3 2.2 1 1 1 2 2 2 1 Dynamin family GTP_EFTU PF00009.27 KFM25314.1 - 0.0038 16.8 0.0 1.5 8.4 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Roc PF08477.13 KFM25314.1 - 0.019 15.2 0.5 0.15 12.2 0.2 2.4 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFM25314.1 - 0.11 12.1 0.0 0.52 9.9 0.0 1.9 2 0 0 2 2 2 0 Ras family COPI_C PF06957.11 KFM25315.1 - 8.1e-110 367.3 0.2 1.4e-98 330.4 0.0 2.2 1 1 1 2 2 2 2 Coatomer (COPI) alpha subunit C-terminus Coatomer_WDAD PF04053.14 KFM25315.1 - 6.1e-98 328.8 0.0 1e-97 328.0 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 KFM25315.1 - 1.5e-41 139.6 18.6 5.9e-08 33.2 0.1 8.4 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM25315.1 - 1.7e-08 34.7 0.4 0.015 15.6 0.0 5.3 4 1 3 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFM25315.1 - 0.023 13.3 11.4 1.5 7.4 0.1 4.0 2 1 2 4 4 4 0 Nucleoporin Nup120/160 Fis1_TPR_C PF14853.6 KFM25315.1 - 0.033 14.3 0.0 0.31 11.1 0.1 2.3 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.17 KFM25315.1 - 0.27 11.5 7.5 2.1 8.7 0.3 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Asp_protease PF09668.10 KFM25316.1 - 3.5e-49 165.7 0.1 5.1e-49 165.2 0.1 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KFM25316.1 - 1.1e-15 57.9 0.2 2.4e-15 56.9 0.1 1.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease ubiquitin PF00240.23 KFM25316.1 - 8e-08 31.9 0.0 1.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Asp_protease_2 PF13650.6 KFM25316.1 - 1.3e-06 29.0 0.3 4.7e-06 27.2 0.1 1.9 2 0 0 2 2 2 1 Aspartyl protease YukD PF08817.10 KFM25316.1 - 0.0022 18.6 0.5 0.027 15.2 0.2 2.7 2 1 1 3 3 3 1 WXG100 protein secretion system (Wss), protein YukD Rad60-SLD PF11976.8 KFM25316.1 - 0.046 13.5 0.0 0.068 13.0 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF3611 PF12263.8 KFM25317.1 - 4.2e-36 124.5 5.8 5.2e-36 124.2 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3611) 7tm_7 PF08395.12 KFM25317.1 - 0.025 13.8 2.6 0.028 13.7 2.6 1.1 1 0 0 1 1 1 0 7tm Chemosensory receptor SUR7 PF06687.12 KFM25317.1 - 2.1 7.9 7.4 5.9 6.5 7.4 1.7 1 1 0 1 1 1 0 SUR7/PalI family Lipase_3 PF01764.25 KFM25319.1 - 1.9e-10 40.8 0.0 7.6e-10 38.8 0.0 1.9 1 1 0 1 1 1 1 Lipase (class 3) Transket_pyr PF02779.24 KFM25320.1 - 3e-45 154.1 0.0 4e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KFM25320.1 - 3.1e-33 114.3 0.0 5.9e-33 113.4 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DUF498 PF04430.14 KFM25320.1 - 0.18 11.9 0.0 0.47 10.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF498/DUF598) FMN_red PF03358.15 KFM25320.1 - 0.2 11.4 0.5 1.8 8.3 0.1 2.1 2 0 0 2 2 2 0 NADPH-dependent FMN reductase TRAPPC10 PF12584.8 KFM25321.1 - 0.00073 19.3 0.0 0.0052 16.5 0.0 2.4 3 0 0 3 3 3 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.8 KFM25321.1 - 0.0064 16.1 0.0 0.0064 16.1 0.0 1.8 3 0 0 3 3 3 1 Foie gras liver health family 1 TPR_2 PF07719.17 KFM25321.1 - 0.025 14.7 0.0 4 7.8 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Gryzun-like PF12742.7 KFM25321.1 - 0.044 13.8 0.0 0.081 12.9 0.0 1.4 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking Acetyltransf_7 PF13508.7 KFM25321.1 - 0.062 13.7 0.1 0.15 12.5 0.1 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Aldedh PF00171.22 KFM25322.1 - 4.5e-164 546.3 4.2 5e-163 542.9 4.2 1.9 1 1 0 1 1 1 1 Aldehyde dehydrogenase family Fasciclin PF02469.22 KFM25323.1 - 1.4e-12 47.9 0.0 2e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain OTT_1508_deam PF14441.6 KFM25323.1 - 0.039 13.9 0.7 0.07 13.2 0.7 1.4 1 0 0 1 1 1 0 OTT_1508-like deaminase UQ_con PF00179.26 KFM25326.1 - 1.3e-44 151.3 0.0 1.4e-44 151.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PMM PF03332.13 KFM25327.1 - 1.8e-103 345.0 0.1 2.1e-103 344.9 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 KFM25327.1 - 0.0038 17.0 0.1 0.15 11.8 0.0 2.7 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFM25327.1 - 0.066 13.6 0.0 0.14 12.6 0.0 1.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase S6PP PF05116.13 KFM25327.1 - 0.072 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase Thioredoxin PF00085.20 KFM25328.1 - 1.1e-26 92.8 0.0 3.9e-23 81.4 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin DnaJ PF00226.31 KFM25328.1 - 1.1e-25 89.5 2.0 1.6e-25 89.0 2.0 1.3 1 0 0 1 1 1 1 DnaJ domain Armet PF10208.9 KFM25328.1 - 8e-08 32.3 0.0 1.3e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Degradation arginine-rich protein for mis-folding Thioredoxin_2 PF13098.6 KFM25328.1 - 0.00061 20.2 0.0 1.6 9.2 0.0 3.6 2 1 0 2 2 2 1 Thioredoxin-like domain Calsequestrin PF01216.17 KFM25328.1 - 0.034 13.2 0.0 0.059 12.4 0.0 1.3 1 0 0 1 1 1 0 Calsequestrin HeH PF12949.7 KFM25328.1 - 0.059 13.1 0.0 0.16 11.7 0.0 1.7 2 0 0 2 2 2 0 HeH/LEM domain SAP PF02037.27 KFM25328.1 - 0.068 12.9 0.3 0.14 12.0 0.3 1.5 1 0 0 1 1 1 0 SAP domain Thioredoxin_9 PF14595.6 KFM25328.1 - 0.076 12.8 0.1 5.1 6.9 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin HyaE PF07449.11 KFM25328.1 - 0.2 11.6 0.0 33 4.5 0.0 2.8 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE GTP_EFTU PF00009.27 KFM25329.1 - 1.5e-58 197.6 0.0 2.2e-58 197.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KFM25329.1 - 8.6e-39 132.1 0.0 1.5e-38 131.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 KFM25329.1 - 4.6e-31 106.7 0.0 1e-30 105.7 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KFM25329.1 - 2.3e-28 98.1 0.1 5.3e-28 96.9 0.1 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KFM25329.1 - 9.2e-17 61.2 0.1 4.2e-16 59.1 0.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KFM25329.1 - 2.2e-06 27.5 0.0 4.5e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 KFM25329.1 - 0.0023 18.0 0.0 0.0047 17.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF442 PF04273.13 KFM25329.1 - 0.017 15.2 0.0 30 4.8 0.0 4.0 3 1 0 3 3 3 0 Putative phosphatase (DUF442) His_Phos_1 PF00300.22 KFM25330.1 - 3.2e-09 36.8 0.0 0.0022 17.7 0.0 2.7 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) Usp PF00582.26 KFM25331.1 - 4.4e-17 62.9 0.4 5.5e-17 62.6 0.4 1.1 1 0 0 1 1 1 1 Universal stress protein family PfkB PF00294.24 KFM25332.1 - 2.2e-34 119.2 1.8 3.3e-34 118.6 1.8 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Lysine_decarbox PF03641.14 KFM25332.1 - 4.1e-23 81.9 0.0 6.8e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 KFM25332.1 - 2e-05 24.2 1.1 4.9e-05 23.0 1.1 1.6 1 1 0 1 1 1 1 SLOG cluster4 family Ponericin PF07442.11 KFM25332.1 - 5.7 7.1 10.4 31 4.7 0.1 3.7 3 0 0 3 3 3 0 Ponericin RCC1 PF00415.18 KFM25333.1 - 2.4e-37 127.3 14.8 2.5e-10 40.8 0.0 6.5 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFM25333.1 - 2.2e-31 107.0 36.1 4e-09 36.0 2.1 7.2 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat JAB PF01398.21 KFM25334.1 - 3.5e-32 110.9 0.0 1.4e-31 109.0 0.0 2.0 3 0 0 3 3 3 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KFM25334.1 - 5.6e-28 97.6 0.0 9.2e-28 96.9 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Mt_ATP_synt PF15704.5 KFM25335.1 - 1e-08 35.3 0.1 1.5e-08 34.8 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase subunit DUF3861 PF12977.7 KFM25335.1 - 0.19 11.9 0.2 0.39 10.9 0.2 1.5 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3861) RRM_1 PF00076.22 KFM25336.1 - 1.2e-15 57.0 0.0 2e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) p450 PF00067.22 KFM25337.1 - 5.3e-73 246.3 0.0 6.3e-73 246.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HisKA_3 PF07730.13 KFM25338.1 - 1.8 9.1 3.4 16 6.1 0.0 4.0 4 0 0 4 4 4 0 Histidine kinase DJ-1_PfpI PF01965.24 KFM25339.1 - 3.5e-40 137.5 0.1 4.2e-40 137.3 0.1 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Spc7 PF08317.11 KFM25340.1 - 0.0019 17.1 10.9 0.0019 17.1 10.9 5.6 2 1 4 6 6 6 3 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 KFM25340.1 - 0.0026 17.8 17.0 0.0026 17.8 17.0 6.7 3 2 3 7 7 7 1 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 KFM25340.1 - 0.0052 17.3 62.0 0.86 10.0 14.6 5.2 3 1 2 5 5 5 4 Fez1 DUF2009 PF09418.10 KFM25340.1 - 0.38 9.8 2.5 0.72 8.9 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) RasGAP_C PF03836.15 KFM25340.1 - 0.83 9.8 12.4 0.98 9.6 6.1 3.2 1 1 1 2 2 2 0 RasGAP C-terminus TraG_N PF07916.11 KFM25340.1 - 2.7 6.8 8.5 5.2 5.8 8.5 1.6 1 0 0 1 1 1 0 TraG-like protein, N-terminal region PKcGMP_CC PF16808.5 KFM25340.1 - 3.7 7.5 10.2 12 5.8 0.6 4.5 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ATPase PF06745.13 KFM25340.1 - 9 5.6 5.8 3.6 6.9 0.2 2.8 2 1 1 3 3 3 0 KaiC Tetraspanin PF00335.20 KFM25341.1 - 0.00025 20.8 11.1 0.00056 19.7 8.1 2.1 1 1 0 2 2 2 1 Tetraspanin family Ferric_reduct PF01794.19 KFM25341.1 - 0.027 14.6 1.2 0.052 13.7 0.1 1.8 1 1 1 2 2 2 0 Ferric reductase like transmembrane component CD20 PF04103.15 KFM25341.1 - 0.27 11.3 12.4 0.78 9.8 12.5 1.7 1 1 0 1 1 1 0 CD20-like family PepSY_TM PF03929.16 KFM25341.1 - 0.87 9.2 6.1 2 8.0 0.2 2.4 2 0 0 2 2 2 0 PepSY-associated TM region DUF4381 PF14316.6 KFM25341.1 - 3 8.1 6.5 0.15 12.3 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Pro_isomerase PF00160.21 KFM25342.1 - 3.4e-44 150.9 0.0 8.7e-44 149.6 0.0 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SYF2 PF08231.12 KFM25342.1 - 1.4e-34 119.8 0.5 1.4e-34 119.8 0.5 2.0 1 1 1 2 2 2 1 SYF2 splicing factor LSM PF01423.22 KFM25343.1 - 1e-14 54.0 0.1 1.2e-14 53.7 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KFM25343.1 - 0.00049 20.2 0.0 0.00055 20.0 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 KFM25343.1 - 0.088 12.9 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain ETF_QO PF05187.13 KFM25343.1 - 0.17 12.0 0.0 0.19 11.9 0.0 1.1 1 0 0 1 1 1 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Metallophos PF00149.28 KFM25345.1 - 1.1e-17 65.2 0.1 1.6e-17 64.7 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 KFM25345.1 - 3.9e-17 62.9 0.1 9.4e-17 61.6 0.1 1.7 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 KFM25345.1 - 6.4e-11 42.7 0.0 2e-10 41.1 0.0 1.9 1 1 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain RbpA PF13397.6 KFM25346.1 - 0.0058 17.2 0.1 0.011 16.3 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase-binding protein Cyt_bd_oxida_II PF02322.15 KFM25346.1 - 0.087 12.2 0.3 9.8 5.4 0.1 2.1 2 0 0 2 2 2 0 Cytochrome bd terminal oxidase subunit II RNB PF00773.19 KFM25348.1 - 2.2e-43 148.9 0.0 1.5e-42 146.1 0.0 1.9 1 1 0 1 1 1 1 RNB domain Ribosomal_L38e PF01781.18 KFM25349.1 - 4.4e-35 119.6 0.5 4.7e-35 119.5 0.5 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family Thioredoxin PF00085.20 KFM25350.1 - 2.3e-07 30.7 0.0 2.6e-07 30.6 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin zf-AN1 PF01428.16 KFM25351.1 - 2.5e-22 78.8 21.4 2.6e-13 49.9 9.6 3.5 4 0 0 4 4 4 2 AN1-like Zinc finger zf-C5HC2 PF02928.16 KFM25351.1 - 0.0022 18.3 17.2 0.023 15.1 2.6 2.7 2 1 0 2 2 2 2 C5HC2 zinc finger zf-C2H2_4 PF13894.6 KFM25351.1 - 0.0056 17.4 26.8 0.49 11.4 0.1 6.3 7 0 0 7 7 7 3 C2H2-type zinc finger Transp_Tc5_C PF04236.15 KFM25351.1 - 0.11 12.8 17.9 0.4 11.1 6.4 2.6 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain zf-C2H2 PF00096.26 KFM25351.1 - 0.24 11.9 19.1 6 7.5 0.0 5.4 5 0 0 5 5 5 0 Zinc finger, C2H2 type FYVE PF01363.21 KFM25351.1 - 3.9 7.7 21.6 1.1 9.4 4.1 3.5 3 1 0 3 3 3 0 FYVE zinc finger zf-C2H2_9 PF16293.5 KFM25351.1 - 8.1 6.4 9.9 5.7 6.9 0.1 3.5 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) FAA_hydrolase PF01557.18 KFM25352.1 - 5.3e-59 199.5 0.0 6.5e-59 199.2 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 KFM25352.1 - 8.1e-08 32.4 0.0 1.7e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal zf-C2HC PF01530.18 KFM25352.1 - 0.32 11.2 0.2 0.32 11.2 0.2 2.0 2 0 0 2 2 2 0 Zinc finger, C2HC type S6PP PF05116.13 KFM25353.1 - 1.7e-35 122.7 0.0 2.7e-24 86.0 0.0 2.2 1 1 1 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase GrpE PF01025.19 KFM25353.1 - 1.9e-26 92.7 0.1 2.8e-26 92.1 0.1 1.2 1 0 0 1 1 1 1 GrpE Hydrolase_3 PF08282.12 KFM25353.1 - 1.7e-13 50.9 0.0 4.2e-10 39.8 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFM25353.1 - 0.13 12.7 4.9 7.1 7.0 4.9 2.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase MMS1_N PF10433.9 KFM25355.1 - 4.2e-134 447.8 0.0 5.8e-134 447.4 0.0 1.1 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KFM25355.1 - 2.5e-86 289.9 0.0 2.2e-85 286.8 0.0 2.1 2 1 1 3 3 3 1 CPSF A subunit region PQQ_3 PF13570.6 KFM25355.1 - 0.14 12.7 0.1 4 8.1 0.0 3.4 3 0 0 3 3 3 0 PQQ-like domain HAD_2 PF13419.6 KFM25356.1 - 6.2e-23 81.8 0.0 1e-22 81.1 0.0 1.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFM25356.1 - 7.5e-18 65.6 0.2 1.9e-17 64.3 0.2 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFM25356.1 - 1.1e-08 35.1 0.0 2.1e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KFM25356.1 - 0.00042 20.8 0.0 0.0018 18.7 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KFM25356.1 - 0.0037 17.3 0.1 6.9 6.8 0.0 3.0 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase DUF1542 PF07564.11 KFM25356.1 - 0.15 12.2 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) Coq4 PF05019.13 KFM25358.1 - 6.7e-81 270.8 0.0 9e-81 270.4 0.0 1.2 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Pkinase_Tyr PF07714.17 KFM25358.1 - 4.3e-47 160.6 0.0 6.1e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM25358.1 - 1.2e-42 146.1 0.0 2e-42 145.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KFM25358.1 - 0.028 14.3 0.0 0.028 14.3 0.0 3.2 5 0 0 5 5 5 0 Phosphotransferase enzyme family DUF4164 PF13747.6 KFM25361.1 - 0.0044 17.3 3.8 0.0044 17.3 3.8 2.7 3 1 0 3 3 3 1 Domain of unknown function (DUF4164) UPF0242 PF06785.11 KFM25361.1 - 0.17 12.0 0.8 0.3 11.2 0.4 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SlyX PF04102.12 KFM25361.1 - 2.7 8.7 9.4 0.3 11.7 1.4 3.0 3 0 0 3 3 3 0 SlyX Amidohydro_1 PF01979.20 KFM25362.1 - 5.1e-60 203.6 0.0 6.2e-60 203.3 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFM25362.1 - 6.9e-13 48.9 0.2 1.7e-09 37.7 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 KFM25362.1 - 0.032 13.5 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 Adenosine/AMP deaminase Exostosin PF03016.15 KFM25363.1 - 5.1e-23 81.7 0.1 7.5e-23 81.2 0.1 1.2 1 0 0 1 1 1 1 Exostosin family Exostosin PF03016.15 KFM25364.1 - 1.9e-19 70.0 0.0 3.2e-18 66.0 0.0 2.1 1 1 1 2 2 2 2 Exostosin family Xan_ur_permease PF00860.20 KFM25366.1 - 3.5e-49 167.5 37.0 5.5e-37 127.4 19.7 2.1 1 1 1 2 2 2 2 Permease family Exostosin PF03016.15 KFM25367.1 - 4.6e-24 85.2 0.1 6.2e-24 84.7 0.1 1.1 1 0 0 1 1 1 1 Exostosin family DUF3181 PF11378.8 KFM25367.1 - 0.026 14.8 0.0 0.051 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3181) Glyco_tranf_2_4 PF13704.6 KFM25368.1 - 1.4e-06 28.7 0.2 3.8e-06 27.3 0.2 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 KFM25368.1 - 9.5e-05 22.2 1.2 0.0016 18.1 0.3 2.6 2 1 0 2 2 2 1 Glycosyltransferase family 92 Mo25 PF08569.11 KFM25370.1 - 3.1e-116 388.3 11.2 3.7e-116 388.1 11.2 1.0 1 0 0 1 1 1 1 Mo25-like VSG_B PF13206.6 KFM25370.1 - 0.24 10.6 0.1 0.37 10.0 0.1 1.2 1 0 0 1 1 1 0 Trypanosomal VSG domain Acyl-CoA_dh_1 PF00441.24 KFM25371.1 - 1.2e-47 161.8 5.8 1.9e-47 161.3 5.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KFM25371.1 - 1.7e-28 99.5 0.0 3.7e-28 98.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KFM25371.1 - 5.7e-26 90.6 0.0 1.2e-25 89.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFM25371.1 - 9.7e-21 74.4 6.0 1.6e-20 73.8 6.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain PC-Esterase PF13839.6 KFM25373.1 - 0.00082 19.2 0.0 0.0028 17.4 0.0 1.8 1 1 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p UvrB PF12344.8 KFM25373.1 - 0.22 11.4 0.0 0.47 10.3 0.0 1.6 1 0 0 1 1 1 0 Ultra-violet resistance protein B zf-TAZ PF02135.16 KFM25375.1 - 5.2e-13 49.3 13.5 5.2e-13 49.3 13.5 3.2 3 1 0 3 3 3 1 TAZ zinc finger ZZ PF00569.17 KFM25375.1 - 1.2e-06 28.2 14.1 1.4e-06 28.0 11.1 2.6 2 0 0 2 2 2 1 Zinc finger, ZZ type Methyltransf_3 PF01596.17 KFM25377.1 - 2.1e-53 180.7 0.0 2.3e-53 180.5 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KFM25377.1 - 3.2e-15 57.1 0.3 5.7e-15 56.2 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM25377.1 - 0.0068 17.1 0.0 0.012 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM25377.1 - 0.12 12.2 0.0 0.2 11.4 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain V-ATPase_C PF03223.15 KFM25378.1 - 0.067 12.6 0.1 0.098 12.0 0.1 1.1 1 0 0 1 1 1 0 V-ATPase subunit C B3 PF02362.21 KFM25380.1 - 0.0065 16.3 0.0 0.0099 15.7 0.0 1.2 1 0 0 1 1 1 1 B3 DNA binding domain Mito_carr PF00153.27 KFM25381.1 - 3.4e-51 171.1 7.7 2.2e-18 66.0 0.2 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.32 KFM25384.1 - 5.1e-17 61.9 2.7 0.0013 19.6 0.0 7.2 6 1 1 7 7 7 5 WD domain, G-beta repeat PD40 PF07676.12 KFM25384.1 - 0.027 14.4 0.0 1.3e+02 2.6 0.0 4.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat RRM_1 PF00076.22 KFM25385.1 - 6.2e-37 125.3 0.0 2.4e-17 62.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SF1-HH PF16275.5 KFM25385.1 - 3.8e-26 91.6 2.5 2e-25 89.3 2.5 2.2 1 1 0 1 1 1 1 Splicing factor 1 helix-hairpin domain DAGK_cat PF00781.24 KFM25385.1 - 8.6e-21 73.9 0.0 1.5e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain KH_1 PF00013.29 KFM25385.1 - 7.6e-09 35.3 0.2 1.9e-08 34.0 0.2 1.7 1 0 0 1 1 1 1 KH domain RRM_7 PF16367.5 KFM25385.1 - 4.3e-05 23.5 0.0 0.025 14.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif zf-CCHC PF00098.23 KFM25385.1 - 0.036 14.2 3.2 0.077 13.1 3.2 1.6 1 0 0 1 1 1 0 Zinc knuckle Chloroa_b-bind PF00504.21 KFM25386.1 - 0.0018 18.8 0.0 0.0033 18.0 0.0 1.5 1 0 0 1 1 1 1 Chlorophyll A-B binding protein BCAS3 PF12490.8 KFM25386.1 - 0.087 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 ketoacyl-synt PF00109.26 KFM25387.1 - 6.5e-57 193.0 1.2 8.6e-57 192.6 0.3 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KFM25387.1 - 7.4e-32 109.8 0.4 7.4e-32 109.8 0.4 1.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 KFM25387.1 - 0.00015 21.2 0.5 0.00046 19.6 0.2 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 KFM25387.1 - 0.0046 16.8 1.8 0.51 10.2 0.5 2.9 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III TerB PF05099.13 KFM25387.1 - 0.0079 16.2 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TerB tRNA-synt_2b PF00587.25 KFM25388.1 - 1.1e-40 139.5 0.0 1.9e-40 138.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) TruB_C_2 PF16198.5 KFM25388.1 - 4.2e-23 81.3 0.9 3.9e-22 78.2 1.2 2.4 2 0 0 2 2 2 1 tRNA pseudouridylate synthase B C-terminal domain TruB_N PF01509.18 KFM25388.1 - 1.1e-20 74.6 0.2 1.4e-18 67.6 0.2 3.1 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 KFM25388.1 - 3.9e-20 71.6 1.5 9.1e-20 70.4 1.5 1.7 1 0 0 1 1 1 1 PUA domain DKCLD PF08068.12 KFM25388.1 - 1.6e-15 56.9 3.8 7.2e-12 45.2 0.8 3.5 2 1 1 3 3 3 2 DKCLD (NUC011) domain HGTP_anticodon PF03129.20 KFM25388.1 - 4.4e-12 46.0 0.0 9.4e-12 44.9 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 KFM25388.1 - 6.1e-12 45.5 0.0 1.3e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain UPF0113 PF03657.13 KFM25388.1 - 0.14 12.4 0.0 0.43 10.9 0.0 1.8 2 0 0 2 2 2 0 UPF0113 PUA domain Methyltransf_25 PF13649.6 KFM25389.1 - 7.1e-12 45.9 0.1 2.5e-11 44.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 KFM25389.1 - 1.7e-10 40.8 0.1 2.8e-10 40.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 KFM25389.1 - 3.7e-10 39.8 0.0 8.9e-10 38.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFM25389.1 - 8.5e-10 39.2 0.1 3e-09 37.4 0.0 2.0 2 1 1 3 3 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM25389.1 - 7.3e-08 32.4 0.0 2.8e-07 30.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KFM25389.1 - 2.7e-06 26.5 0.1 4.1e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 KFM25389.1 - 2.3e-05 24.0 0.1 3.7e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KFM25389.1 - 3.7e-05 24.4 0.0 8.1e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KFM25389.1 - 0.0001 21.7 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 KFM25389.1 - 0.00084 19.3 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KFM25389.1 - 0.0039 18.2 0.1 0.017 16.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 KFM25389.1 - 0.0052 16.8 0.0 0.0098 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KFM25389.1 - 0.0079 16.3 0.0 0.035 14.2 0.0 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 KFM25389.1 - 0.023 14.0 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain DOT1 PF08123.13 KFM25389.1 - 0.025 14.1 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Cons_hypoth95 PF03602.15 KFM25389.1 - 0.045 13.4 0.2 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical protein 95 PRMT5_C PF17286.2 KFM25389.1 - 0.071 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 PRMT5 oligomerisation domain TehB PF03848.14 KFM25389.1 - 0.078 12.4 0.5 0.2 11.1 0.1 1.9 2 1 0 2 2 2 0 Tellurite resistance protein TehB PRMT5 PF05185.16 KFM25389.1 - 0.081 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase PCMT PF01135.19 KFM25389.1 - 0.095 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 KFM25389.1 - 0.097 11.7 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.9 KFM25389.1 - 0.11 12.2 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Met_10 PF02475.16 KFM25389.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein LON_substr_bdg PF02190.16 KFM25390.1 - 5.1e-11 42.8 0.0 7.9e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 KFM25390.1 - 1e-10 41.2 14.7 2.6e-10 40.0 14.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFM25390.1 - 4.8e-09 35.9 9.8 1.1e-08 34.8 9.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM25390.1 - 1.7e-07 31.5 13.7 4.3e-07 30.2 13.7 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KFM25390.1 - 1.7e-06 27.8 13.2 3.7e-06 26.7 13.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFM25390.1 - 2.2e-06 27.6 13.9 5.6e-06 26.3 13.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFM25390.1 - 5.1e-06 26.3 12.1 1.3e-05 25.0 12.1 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFM25390.1 - 7.1e-06 26.1 14.0 1.6e-05 25.0 14.0 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KFM25390.1 - 0.0012 18.6 4.7 0.0028 17.5 4.7 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 KFM25390.1 - 0.0037 17.1 13.4 0.023 14.6 13.6 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 U-box PF04564.15 KFM25390.1 - 0.0071 16.5 0.1 0.015 15.4 0.1 1.5 1 0 0 1 1 1 1 U-box domain zf-RING_10 PF16685.5 KFM25390.1 - 0.015 15.4 8.9 0.039 14.1 8.9 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 Rad50_zn_hook PF04423.14 KFM25390.1 - 0.047 13.5 1.6 0.27 11.1 0.1 2.7 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_4 PF14570.6 KFM25390.1 - 0.085 12.7 11.5 0.29 10.9 11.6 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 KFM25390.1 - 0.61 9.9 8.0 1.2 9.0 8.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FYVE PF01363.21 KFM25390.1 - 1.8 8.7 10.6 0.66 10.2 0.1 2.8 2 1 0 2 2 2 0 FYVE zinc finger Nkap_C PF06047.11 KFM25391.1 - 5.7e-41 138.8 2.0 6.4e-41 138.6 2.0 1.0 1 0 0 1 1 1 1 NF-kappa-B-activating protein C-terminal domain DUF2989 PF11207.8 KFM25391.1 - 0.048 13.4 0.0 0.048 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2989) AMP-binding PF00501.28 KFM25392.1 - 6.4e-93 311.6 0.1 8.1e-93 311.3 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFM25392.1 - 9.6e-22 77.8 0.3 2.3e-21 76.6 0.3 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KFM25392.1 - 3.6e-21 74.8 1.6 9.6e-21 73.5 1.6 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus DUF525 PF04379.14 KFM25393.1 - 3.9e-14 52.6 0.0 7e-14 51.8 0.0 1.4 1 1 0 1 1 1 1 ApaG domain SMI1_KNR4 PF09346.10 KFM25393.1 - 2.7e-05 24.6 0.0 4.1e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) RRM_1 PF00076.22 KFM25394.1 - 5.7e-21 74.1 0.0 6.4e-21 74.0 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFM25394.1 - 0.041 13.9 0.0 0.048 13.7 0.0 1.1 1 0 0 1 1 1 0 RNA binding motif RRM_1 PF00076.22 KFM25395.1 - 2.2e-20 72.2 0.0 2.8e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFM25395.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KFM25395.1 - 0.14 12.2 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 RNA binding motif V-ATPase_H_N PF03224.14 KFM25396.1 - 2.7e-54 184.6 0.0 8.4e-54 183.0 0.0 1.6 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 KFM25396.1 - 1.5e-34 118.6 0.0 6.2e-34 116.6 0.0 1.9 2 0 0 2 2 2 1 V-ATPase subunit H TetR_C_36 PF18598.1 KFM25396.1 - 0.021 14.8 1.4 1.5 8.8 0.0 3.2 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain aGPT-Pplase1 PF18723.1 KFM25396.1 - 0.075 12.5 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 1 Arm_2 PF04826.13 KFM25396.1 - 0.22 11.0 0.0 0.4 10.1 0.0 1.3 1 0 0 1 1 1 0 Armadillo-like Arm PF00514.23 KFM25396.1 - 1 9.5 8.7 5 7.3 0.0 4.0 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat ketoacyl-synt PF00109.26 KFM25397.1 - 6.6e-52 176.6 1.9 1.2e-51 175.7 1.9 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KFM25397.1 - 3.6e-32 110.8 0.5 7.1e-32 109.9 0.5 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 KFM25397.1 - 9.3e-05 21.9 0.4 0.00016 21.1 0.4 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Cuticle_1 PF08140.11 KFM25397.1 - 0.01 15.9 0.0 0.065 13.3 0.0 2.3 2 0 0 2 2 2 1 Crustacean cuticle protein repeat KAsynt_C_assoc PF16197.5 KFM25397.1 - 0.085 13.3 0.1 0.16 12.4 0.1 1.5 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension SAP30_Sin3_bdg PF13867.6 KFM25398.1 - 2.2e-13 50.3 0.0 3.9e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 DUF974 PF06159.13 KFM25399.1 - 5.5e-27 95.1 0.0 8.6e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF974) TPR_14 PF13428.6 KFM25399.1 - 3.2e-18 64.8 27.2 0.00023 21.7 2.1 8.6 4 2 4 8 8 8 6 Tetratricopeptide repeat TPR_19 PF14559.6 KFM25399.1 - 7e-13 48.9 9.7 0.021 15.3 1.5 5.3 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 KFM25399.1 - 2.2e-11 44.2 26.3 0.0015 19.2 1.8 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 KFM25399.1 - 9.1e-11 41.0 17.5 0.072 13.2 0.0 8.5 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFM25399.1 - 1.8e-05 24.8 1.2 2.5 8.7 0.0 6.2 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFM25399.1 - 6e-05 22.9 0.1 9.7 6.7 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFM25399.1 - 6.9e-05 23.1 12.3 4.4 7.7 0.6 6.3 3 2 3 6 6 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFM25399.1 - 0.00013 21.6 0.1 11 6.0 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_15 PF13429.6 KFM25399.1 - 0.00086 18.6 16.1 0.005 16.1 10.1 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KFM25399.1 - 0.0035 17.3 5.4 1.5 8.9 0.4 5.4 6 2 1 7 7 7 1 Mad3/BUB1 homology region 1 FAT PF02259.23 KFM25399.1 - 0.0059 15.9 1.6 0.046 12.9 0.6 2.3 2 1 0 2 2 2 1 FAT domain TPR_11 PF13414.6 KFM25399.1 - 0.0066 16.1 0.0 27 4.6 0.0 4.6 4 1 0 4 4 4 0 TPR repeat TPR_10 PF13374.6 KFM25399.1 - 0.02 14.8 3.1 32 4.6 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Suf PF05843.14 KFM25399.1 - 0.15 12.0 0.0 29 4.5 0.0 3.0 2 2 1 3 3 3 0 Suppressor of forked protein (Suf) TPR_6 PF13174.6 KFM25399.1 - 0.27 12.0 8.1 1e+02 3.8 0.2 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 KFM25399.1 - 8.1 7.4 17.5 25 5.9 2.3 6.4 5 1 0 5 5 5 0 Tetratricopeptide repeat Epimerase PF01370.21 KFM25400.1 - 2.9e-20 72.8 0.0 9e-20 71.2 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFM25400.1 - 5.6e-15 55.7 0.0 1e-14 54.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KFM25400.1 - 9.9e-14 51.5 0.0 2.5e-06 27.1 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KFM25400.1 - 7.6e-06 25.7 0.0 2.4e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 KFM25400.1 - 1.1e-05 24.8 0.0 2.3e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KFM25400.1 - 0.00054 19.1 0.0 0.03 13.3 0.0 2.2 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KFM25400.1 - 0.00059 19.3 0.0 0.001 18.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Glyco_trans_4_4 PF13579.6 KFM25400.1 - 0.00071 20.1 0.3 0.0018 18.7 0.1 1.8 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain KR PF08659.10 KFM25400.1 - 0.0034 17.3 0.0 0.005 16.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Glyco_transf_4 PF13439.6 KFM25400.1 - 0.015 15.3 0.0 0.034 14.2 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 ApbA PF02558.16 KFM25400.1 - 0.069 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MIOX PF05153.15 KFM25401.1 - 2.2e-37 129.0 0.0 3.6e-37 128.3 0.0 1.2 1 0 0 1 1 1 1 Myo-inositol oxygenase zf-RING_2 PF13639.6 KFM25401.1 - 4.4e-11 42.9 8.6 4.4e-11 42.9 8.6 2.0 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KFM25401.1 - 4.5e-08 33.3 5.8 1.3e-07 31.8 5.8 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KFM25401.1 - 1.2e-07 31.6 8.2 4e-07 29.9 8.2 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFM25401.1 - 1.4e-06 28.1 9.9 2.8e-06 27.0 9.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM25401.1 - 1.8e-06 27.7 8.6 3.4e-06 26.8 8.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFM25401.1 - 2.3e-06 27.2 4.5 5.1e-06 26.1 4.5 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 KFM25401.1 - 5.3e-05 23.1 7.5 0.00011 22.1 7.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KFM25401.1 - 9.8e-05 22.3 2.6 0.00028 20.9 2.6 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KFM25401.1 - 0.00024 20.9 5.6 0.00052 19.8 5.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 KFM25401.1 - 0.021 14.6 3.8 0.048 13.5 3.8 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Rad50_zn_hook PF04423.14 KFM25401.1 - 0.095 12.6 0.3 0.87 9.5 0.1 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif Prok-RING_1 PF14446.6 KFM25401.1 - 0.24 11.4 7.6 0.098 12.6 3.7 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Prok-RING_4 PF14447.6 KFM25401.1 - 0.3 11.0 5.4 6.1 6.8 3.1 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KFM25401.1 - 0.36 11.0 9.0 0.83 9.9 9.0 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 KFM25401.1 - 0.39 10.4 7.2 0.69 9.6 5.6 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Sfi1 PF08457.10 KFM25404.1 - 0.0011 17.6 37.2 0.0018 16.9 7.6 3.2 2 1 1 3 3 3 3 Sfi1 spindle body protein NDUFB10 PF10249.9 KFM25405.1 - 0.0089 16.5 0.4 0.011 16.3 0.4 1.3 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 IL10 PF00726.17 KFM25405.1 - 0.094 12.2 0.1 0.11 12.0 0.1 1.1 1 0 0 1 1 1 0 Interleukin 10 Pterin_4a PF01329.19 KFM25406.1 - 2.3e-27 95.0 0.0 3e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Ribosomal_L34 PF00468.17 KFM25408.1 - 1.9e-16 59.7 8.0 3.3e-16 59.0 8.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 Lon_C PF05362.13 KFM25409.1 - 6.9e-45 153.1 0.1 1.2e-44 152.4 0.1 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 KFM25409.1 - 2.8e-21 76.3 0.0 5.3e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFM25409.1 - 1.9e-09 37.7 0.0 3.5e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 KFM25409.1 - 2.6e-07 30.5 0.0 4.5e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.14 KFM25409.1 - 0.00026 21.1 0.0 0.00045 20.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KFM25409.1 - 0.00051 20.3 0.1 0.034 14.4 0.1 2.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KFM25409.1 - 0.00096 18.9 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 KFM25409.1 - 0.0017 18.8 2.1 0.0086 16.5 0.6 2.7 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KFM25409.1 - 0.002 17.9 0.0 0.013 15.2 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 KFM25409.1 - 0.0048 16.5 0.1 0.024 14.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KFM25409.1 - 0.0055 16.6 0.0 0.063 13.2 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA_PrkA PF08298.11 KFM25409.1 - 0.0067 15.4 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 PrkA AAA domain NTPase_1 PF03266.15 KFM25409.1 - 0.018 15.0 0.0 0.47 10.3 0.0 2.5 2 1 1 3 3 3 0 NTPase AAA_24 PF13479.6 KFM25409.1 - 0.052 13.3 0.0 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KFM25409.1 - 0.09 12.9 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 KFM25409.1 - 0.091 12.6 0.0 0.25 11.2 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KFM25409.1 - 0.2 12.1 0.0 0.82 10.1 0.0 2.0 2 0 0 2 2 2 0 RNA helicase WD40 PF00400.32 KFM25410.1 - 3.2e-10 40.4 0.3 0.47 11.4 0.0 5.7 5 0 0 5 5 5 3 WD domain, G-beta repeat zf-CCHC_4 PF14392.6 KFM25410.1 - 2.7 7.8 4.0 5.9 6.7 4.0 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 KFM25410.1 - 3.9 7.4 7.0 5.3 7.0 0.5 2.6 2 0 0 2 2 2 0 Zinc knuckle HUN PF08729.10 KFM25411.1 - 4.4e-09 36.2 4.0 9.9e-09 35.1 3.5 1.8 2 0 0 2 2 2 1 HPC2 and ubinuclein domain ResB PF05140.14 KFM25413.1 - 1e-80 271.9 4.1 1.4e-26 93.3 4.2 4.8 2 1 1 3 3 3 3 ResB-like family AAA_5 PF07728.14 KFM25413.1 - 0.03 14.3 0.0 12 5.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Kinesin PF00225.23 KFM25415.1 - 5.9e-68 229.2 0.0 1.7e-61 208.0 0.0 2.3 1 1 1 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 KFM25415.1 - 2.5e-23 82.7 0.0 1.5e-18 67.1 0.0 2.5 1 1 1 2 2 2 2 Microtubule binding DivIC PF04977.15 KFM25415.1 - 0.011 15.5 2.5 0.011 15.5 2.5 4.2 4 1 0 4 4 4 0 Septum formation initiator ING PF12998.7 KFM25415.1 - 1 10.0 3.0 4.8 7.8 0.2 2.9 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding CLZ PF16526.5 KFM25415.1 - 2.2 8.7 23.0 1.3 9.4 0.3 5.7 4 1 1 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels PADR1 PF08063.12 KFM25416.1 - 0.084 12.7 0.1 0.12 12.2 0.1 1.2 1 0 0 1 1 1 0 PADR1 (NUC008) domain RRM_1 PF00076.22 KFM25417.1 - 1.1e-16 60.4 0.0 1.4e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFM25417.1 - 0.062 13.3 0.1 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_8 PF11835.8 KFM25417.1 - 0.098 12.9 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 RRM-like domain Abhydrolase_6 PF12697.7 KFM25418.1 - 8e-11 43.0 1.3 8e-11 43.0 1.3 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFM25418.1 - 7.3e-05 22.1 0.0 0.00021 20.6 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFM25418.1 - 0.00019 21.2 0.6 0.00079 19.1 0.0 2.3 4 0 0 4 4 4 1 alpha/beta hydrolase fold AAA_12 PF13087.6 KFM25419.1 - 4.7e-25 88.4 0.0 6.5e-25 87.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFM25419.1 - 2.8e-16 60.1 0.0 4.1e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFM25419.1 - 2.5e-08 33.9 1.5 2.5e-08 33.9 1.5 2.0 1 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KFM25419.1 - 4e-07 30.5 0.1 7.7e-07 29.5 0.1 1.5 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KFM25419.1 - 6.8e-07 29.0 0.2 1.6e-06 27.8 0.2 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 KFM25419.1 - 0.00019 21.2 0.1 0.0019 18.0 0.0 2.1 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 KFM25419.1 - 0.033 13.7 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA PF00004.29 KFM25419.1 - 0.24 11.8 0.6 1.1 9.6 0.1 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CLASP_N PF12348.8 KFM25420.1 - 2.3e-10 40.4 0.0 1.8e-08 34.2 0.0 2.9 2 1 0 3 3 3 1 CLASP N terminal HEAT PF02985.22 KFM25420.1 - 3.2e-06 26.9 13.6 7.1 7.2 0.1 7.7 9 0 0 9 9 9 4 HEAT repeat HEAT_2 PF13646.6 KFM25420.1 - 6.2e-05 23.3 18.7 0.014 15.8 1.2 5.3 2 2 3 5 5 5 3 HEAT repeats CLASP_N PF12348.8 KFM25421.1 - 0.00065 19.3 0.0 0.017 14.7 0.0 2.6 2 0 0 2 2 2 1 CLASP N terminal Fis1_TPR_C PF14853.6 KFM25423.1 - 2e-14 53.4 0.1 3.6e-14 52.5 0.1 1.5 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 KFM25423.1 - 1.4e-05 24.6 0.0 3.5e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 Fis1 N-terminal tetratricopeptide repeat TPR_16 PF13432.6 KFM25423.1 - 0.0083 16.8 3.0 2 9.1 0.3 2.4 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFM25423.1 - 0.009 16.5 1.9 0.018 15.6 0.5 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFM25423.1 - 0.016 16.0 2.3 2.9 9.0 0.4 2.8 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFM25423.1 - 0.022 15.3 0.2 1 10.1 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat BPL_LplA_LipB PF03099.19 KFM25424.1 - 1.6e-18 66.9 0.0 2.2e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 KFM25424.1 - 6.2e-07 29.2 0.0 1.1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain Alba PF01918.21 KFM25425.1 - 5.9e-13 48.4 0.1 9.9e-13 47.7 0.1 1.3 1 0 0 1 1 1 1 Alba Rpp20 PF12328.8 KFM25425.1 - 2.2e-05 24.4 0.1 3.4e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Cpn60_TCP1 PF00118.24 KFM25426.1 - 1.6e-149 498.7 0.4 2.9e-149 497.8 0.4 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1681 PF07933.14 KFM25427.1 - 2.8e-44 150.4 0.0 3.6e-44 150.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) BHD_3 PF10405.9 KFM25427.1 - 0.15 12.4 0.0 0.26 11.7 0.0 1.3 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 3 DJ-1_PfpI PF01965.24 KFM25428.1 - 1.3e-06 28.3 0.0 2.7e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KFM25428.1 - 0.1 12.3 0.1 0.35 10.5 0.0 1.9 2 0 0 2 2 2 0 ThiJ/PfpI family-like Rad17 PF03215.15 KFM25429.1 - 7.6e-06 26.0 0.0 1.5e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 KFM25429.1 - 2.9e-05 24.5 0.0 5.5e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KFM25429.1 - 0.0015 18.8 0.0 0.0039 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFM25429.1 - 0.002 18.3 0.0 0.0049 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFM25429.1 - 0.0023 18.3 0.0 0.0098 16.3 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.6 KFM25429.1 - 0.0035 17.8 0.0 0.0071 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFM25429.1 - 0.0055 17.3 0.0 0.0094 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KFM25429.1 - 0.01 15.6 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 KFM25429.1 - 0.035 14.6 0.0 0.067 13.7 0.0 1.3 1 0 0 1 1 1 0 ABC transporter RuvB_N PF05496.12 KFM25429.1 - 0.04 13.7 0.0 0.082 12.6 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KFM25429.1 - 0.074 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KFM25429.1 - 0.08 13.3 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 RNA helicase Cytidylate_kin PF02224.18 KFM25429.1 - 0.089 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase AAA_22 PF13401.6 KFM25429.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain dNK PF01712.19 KFM25429.1 - 0.16 11.8 0.0 0.25 11.2 0.0 1.1 1 0 0 1 1 1 0 Deoxynucleoside kinase WD40 PF00400.32 KFM25430.1 - 2.1e-21 75.8 5.7 2.3e-06 28.2 0.0 5.8 6 0 0 6 6 5 3 WD domain, G-beta repeat zf-RING_2 PF13639.6 KFM25430.1 - 8e-14 51.7 3.6 1.5e-13 50.9 3.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFM25430.1 - 1.8e-10 40.5 2.7 3.1e-10 39.7 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFM25430.1 - 4.3e-10 39.7 1.9 9.4e-10 38.6 1.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KFM25430.1 - 2.9e-09 36.5 0.8 2.9e-09 36.5 0.8 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 KFM25430.1 - 3.8e-07 29.9 1.3 6.8e-07 29.1 1.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM25430.1 - 2.2e-06 27.5 2.2 5.2e-06 26.3 2.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFM25430.1 - 1.9e-05 24.6 4.5 4.6e-05 23.4 4.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFM25430.1 - 2.1e-05 24.3 1.9 3.9e-05 23.4 1.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFM25430.1 - 3.3e-05 23.6 2.6 6.2e-05 22.8 2.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 ANAPC4_WD40 PF12894.7 KFM25430.1 - 0.00071 19.8 0.0 2.5 8.4 0.0 3.0 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain zf-ANAPC11 PF12861.7 KFM25430.1 - 0.00073 19.5 0.8 0.0016 18.5 0.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KFM25430.1 - 0.014 15.0 1.8 0.032 13.8 1.8 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 KFM25430.1 - 0.021 14.9 1.0 0.19 11.9 2.1 2.1 2 1 0 2 2 1 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 KFM25430.1 - 0.043 14.1 2.5 0.082 13.2 2.5 1.5 1 0 0 1 1 1 0 RING-like domain Rad50_zn_hook PF04423.14 KFM25430.1 - 0.095 12.6 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-RING_4 PF14570.6 KFM25430.1 - 0.42 10.5 2.6 0.78 9.6 2.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 KFM25430.1 - 1 9.6 3.3 5 7.4 3.3 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain Acetyltransf_1 PF00583.25 KFM25432.1 - 8e-15 55.1 0.1 1.1e-14 54.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFM25432.1 - 6.4e-10 39.3 0.1 1e-09 38.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFM25432.1 - 7e-10 38.9 0.0 1.1e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFM25432.1 - 3.2e-07 30.2 0.1 4.7e-07 29.7 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 KFM25432.1 - 5e-05 23.0 0.0 0.0001 22.0 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KFM25432.1 - 0.003 18.2 0.0 0.0047 17.6 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KFM25432.1 - 0.18 11.9 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain LBR_tudor PF09465.10 KFM25433.1 - 4.6e-06 26.3 0.0 8.4e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain MRI PF15325.6 KFM25433.1 - 0.16 13.1 0.5 0.35 12.0 0.5 1.5 1 0 0 1 1 1 0 Modulator of retrovirus infection UDPGP PF01704.18 KFM25434.1 - 9.2e-25 87.1 0.0 1.9e-24 86.1 0.0 1.4 2 0 0 2 2 2 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 KFM25434.1 - 0.3 11.4 9.5 1.2 9.5 8.1 2.5 2 1 0 2 2 2 0 MobA-like NTP transferase domain GrpE PF01025.19 KFM25435.1 - 2.7e-38 131.3 0.0 3e-38 131.1 0.0 1.1 1 0 0 1 1 1 1 GrpE EccE PF11203.8 KFM25435.1 - 0.022 15.1 0.1 0.022 15.1 0.1 2.6 1 1 2 3 3 3 0 Putative type VII ESX secretion system translocon, EccE Vir_act_alpha_C PF10400.9 KFM25435.1 - 0.055 14.1 0.1 0.19 12.4 0.2 2.0 2 1 0 2 2 2 0 Virulence activator alpha C-term DUF3235 PF11574.8 KFM25435.1 - 0.1 13.5 0.5 0.1 13.5 0.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3235) Opacity PF02462.15 KFM25435.1 - 0.18 11.9 0.1 0.25 11.4 0.1 1.3 1 0 0 1 1 1 0 Opacity family porin protein Q_salvage PF10343.9 KFM25436.1 - 9.6e-75 251.8 0.0 1.4e-74 251.2 0.0 1.2 1 1 0 1 1 1 1 Potential Queuosine, Q, salvage protein family Methyltransf_11 PF08241.12 KFM25437.1 - 2.2e-10 41.0 0.0 3.7e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM25437.1 - 1.4e-05 25.7 0.0 5.2e-05 23.9 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM25437.1 - 0.00035 21.3 0.0 0.00082 20.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM25437.1 - 0.00042 20.1 0.0 0.00054 19.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.18 KFM25437.1 - 0.001 18.9 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 DNA methylase MetW PF07021.12 KFM25437.1 - 0.0049 16.5 0.0 0.0058 16.2 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_23 PF13489.6 KFM25437.1 - 0.007 16.2 0.0 0.0091 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFM25437.1 - 0.042 13.2 0.0 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 KFM25437.1 - 0.13 12.1 0.0 0.17 11.7 0.0 1.4 1 1 0 1 1 1 0 Hypothetical methyltransferase Bin3 PF06859.12 KFM25437.1 - 0.16 12.6 0.0 1.4 9.6 0.0 2.0 2 0 0 2 2 2 0 Bicoid-interacting protein 3 (Bin3) Ras PF00071.22 KFM25438.1 - 6.2e-50 169.0 0.0 8e-50 168.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM25438.1 - 6.3e-30 103.9 0.0 1e-29 103.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM25438.1 - 1.6e-10 40.8 0.0 2.3e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.22 KFM25438.1 - 2.3e-05 24.7 0.1 0.00014 22.2 0.1 2.1 1 1 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.23 KFM25438.1 - 0.0009 19.3 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATPase PF06745.13 KFM25438.1 - 0.025 13.9 0.1 0.037 13.4 0.1 1.2 1 0 0 1 1 1 0 KaiC Pox_A32 PF04665.12 KFM25438.1 - 0.025 14.0 0.0 0.048 13.1 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein G-alpha PF00503.20 KFM25438.1 - 0.046 12.9 1.0 2.2 7.4 0.1 2.5 2 1 1 3 3 3 0 G-protein alpha subunit AAA_7 PF12775.7 KFM25438.1 - 0.052 13.1 0.1 0.098 12.2 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KFM25438.1 - 0.059 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KFM25438.1 - 0.066 13.1 0.1 8.3 6.3 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase TsaE PF02367.17 KFM25438.1 - 0.083 12.9 0.0 0.25 11.3 0.1 1.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KFM25438.1 - 0.12 12.5 0.1 0.24 11.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain ArgoMid PF16487.5 KFM25438.1 - 0.14 12.4 0.1 0.35 11.1 0.0 1.8 2 0 0 2 2 2 0 Mid domain of argonaute Gtr1_RagA PF04670.12 KFM25438.1 - 0.14 11.4 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region CNOT1_TTP_bind PF16417.5 KFM25439.1 - 3e-30 104.8 0.0 4.8e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_CAF1_bind PF16415.5 KFM25439.1 - 1.2e-27 96.8 0.0 1.7e-27 96.2 0.0 1.2 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain Not1 PF04054.15 KFM25439.1 - 9.4e-09 34.6 0.0 1.5e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 SPT_ssu-like PF11779.8 KFM25440.1 - 8.6e-06 25.3 2.1 1.3e-05 24.7 2.1 1.3 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like TPM_phosphatase PF04536.14 KFM25441.1 - 1.2e-12 48.1 0.0 1.5e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 TPM domain ImcF-related_N PF14331.6 KFM25441.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.5 2 0 0 2 2 2 0 ImcF-related N-terminal domain Lactamase_B_2 PF12706.7 KFM25442.1 - 2.8e-15 56.4 0.8 1.1e-12 47.9 1.3 3.2 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 KFM25442.1 - 7.7e-13 47.9 0.0 1.9e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.27 KFM25442.1 - 6.1e-05 23.1 0.9 0.00018 21.6 0.2 2.0 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily DUF3082 PF11282.8 KFM25443.1 - 1.4e-12 47.6 5.1 2.6e-12 46.8 5.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3082) DEAD PF00270.29 KFM25444.1 - 1e-26 93.8 0.0 1.5e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM25444.1 - 2.7e-18 66.3 0.0 1.2e-17 64.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM25444.1 - 0.0061 16.6 0.0 0.0081 16.2 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KFM25444.1 - 0.017 14.5 0.0 0.057 12.8 0.0 1.7 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit SNF2_N PF00176.23 KFM25444.1 - 0.051 12.3 0.0 0.079 11.7 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain FANC_SAP PF18081.1 KFM25444.1 - 0.17 12.0 1.2 34 4.7 0.0 3.4 3 0 0 3 3 3 0 Fanconi anemia-associated nuclease SAP domain DUF202 PF02656.15 KFM25445.1 - 1.3e-12 47.9 0.3 1.3e-12 47.9 0.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) MFS_2 PF13347.6 KFM25445.1 - 0.0073 14.9 0.4 0.0073 14.9 0.4 1.4 2 0 0 2 2 2 1 MFS/sugar transport protein Polysacc_synt_C PF14667.6 KFM25445.1 - 0.0076 16.3 0.4 0.035 14.2 0.1 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis C-terminal domain UbiA PF01040.18 KFM25445.1 - 0.028 13.7 0.4 0.066 12.5 0.4 1.7 1 1 0 1 1 1 0 UbiA prenyltransferase family DUF5453 PF17534.2 KFM25445.1 - 0.17 11.9 1.7 0.26 11.2 1.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5453) POT1 PF02765.17 KFM25446.1 - 1.4e-10 41.2 0.0 2.4e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 POT1PC PF16686.5 KFM25446.1 - 1.6e-06 28.1 0.0 9.7e-06 25.5 0.0 2.0 2 0 0 2 2 2 1 ssDNA-binding domain of telomere protection protein Glyoxalase_4 PF13669.6 KFM25447.1 - 7.4e-18 64.8 0.0 8.8e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KFM25447.1 - 5.5e-05 23.4 0.0 6.2e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 KFM25447.1 - 0.00053 20.2 0.0 0.00058 20.0 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KFM25447.1 - 0.014 16.2 0.1 0.023 15.5 0.1 1.3 1 1 0 1 1 1 0 Glyoxalase-like domain DUF1338 PF07063.13 KFM25447.1 - 0.14 11.3 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1338) Aldo_ket_red PF00248.21 KFM25448.1 - 3.6e-73 246.3 0.0 4.2e-73 246.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KFM25449.1 - 3.9e-70 236.4 0.0 4.4e-70 236.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family YdiH PF15930.5 KFM25449.1 - 0.019 15.1 0.1 0.055 13.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function Pkinase PF00069.25 KFM25450.1 - 5.3e-39 134.2 0.0 6.9e-39 133.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM25450.1 - 1.6e-38 132.5 0.0 2.2e-38 132.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase GAF_3 PF13492.6 KFM25450.1 - 0.0017 18.7 0.0 0.0048 17.2 0.0 1.8 1 0 0 1 1 1 1 GAF domain Kdo PF06293.14 KFM25450.1 - 0.092 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.16 KFM25450.1 - 0.1 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 ABC1 family Acetyltransf_6 PF13480.7 KFM25450.1 - 0.3 11.3 4.0 9.4 6.4 0.1 3.3 2 1 1 3 3 3 0 Acetyltransferase (GNAT) domain Sugar_tr PF00083.24 KFM25451.1 - 2.4e-116 389.3 30.9 2.8e-116 389.1 30.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFM25451.1 - 4.3e-22 78.5 27.8 4.3e-22 78.5 27.8 2.7 1 1 2 3 3 3 2 Major Facilitator Superfamily Rpn3_C PF08375.11 KFM25452.1 - 1.7e-18 66.8 0.0 3.6e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 KFM25452.1 - 3.2e-11 43.7 0.0 1.1e-10 42.0 0.0 2.0 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.17 KFM25452.1 - 0.00017 21.4 0.4 0.00017 21.4 0.4 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFM25452.1 - 0.0017 18.9 4.4 0.028 15.1 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFM25452.1 - 0.0033 17.2 0.2 0.01 15.6 0.2 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat PreAtp-grasp PF18604.1 KFM25452.1 - 0.059 13.0 0.9 0.24 11.0 0.5 2.2 2 0 0 2 2 2 0 Pre ATP-grasp domain Pyr_redox PF00070.27 KFM25452.1 - 0.11 13.0 0.7 0.22 12.1 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KFM25453.1 - 1.7e-74 251.8 0.0 2e-74 251.5 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFM25453.1 - 3.7e-14 52.7 0.1 7.4e-14 51.7 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFM25453.1 - 1.6e-05 24.7 0.0 0.038 13.6 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase MCRA PF06100.11 KFM25453.1 - 4.5e-05 22.5 0.0 0.0019 17.1 0.0 2.1 2 0 0 2 2 2 1 MCRA family Pyr_redox_2 PF07992.14 KFM25453.1 - 6.2e-05 22.4 0.1 0.02 14.1 0.2 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFM25453.1 - 0.00013 22.5 0.0 0.52 10.9 0.2 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KFM25453.1 - 0.0028 17.1 0.0 0.0045 16.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KFM25453.1 - 0.0058 15.9 0.2 0.025 13.8 0.4 1.9 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 KFM25453.1 - 0.0082 15.3 1.4 0.022 13.9 1.5 1.6 2 0 0 2 2 2 1 FAD binding domain DUF2862 PF11061.8 KFM25453.1 - 0.056 13.3 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2862) FMO-like PF00743.19 KFM25453.1 - 0.058 11.8 0.0 0.083 11.3 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Thi4 PF01946.17 KFM25453.1 - 0.097 11.9 0.2 0.19 10.9 0.2 1.4 1 0 0 1 1 1 0 Thi4 family TetR_C_16 PF17920.1 KFM25453.1 - 0.11 12.7 0.2 0.37 11.0 0.0 1.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain HI0933_like PF03486.14 KFM25453.1 - 0.15 10.7 0.1 0.57 8.8 0.8 1.6 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.14 KFM25453.1 - 0.2 10.5 0.2 12 4.6 0.0 2.3 2 0 0 2 2 2 0 Tryptophan halogenase Sgf11 PF08209.11 KFM25454.1 - 2.6e-16 58.9 0.7 4e-16 58.3 0.7 1.2 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.6 KFM25454.1 - 0.0017 18.2 1.2 0.0031 17.4 1.2 1.4 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-C3HC PF07967.13 KFM25455.1 - 1.6e-10 41.2 0.0 3.8e-09 36.7 0.0 2.6 3 0 0 3 3 3 1 C3HC zinc finger-like Rsm1 PF08600.10 KFM25455.1 - 6e-05 23.1 0.4 2.2 8.5 0.1 3.3 3 0 0 3 3 3 2 Rsm1-like SH3_16 PF18348.1 KFM25455.1 - 4.9 7.0 6.6 0.34 10.7 0.6 2.1 2 0 0 2 2 2 0 Bacterial dipeptidyl-peptidase Sh3 domain Ribosomal_S13 PF00416.22 KFM25456.1 - 6.6e-52 175.3 0.7 7.6e-52 175.1 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 PP28 PF10252.9 KFM25456.1 - 0.1 13.1 0.9 0.22 12.0 0.4 1.7 2 0 0 2 2 2 0 Casein kinase substrate phosphoprotein PP28 FbpA PF05833.11 KFM25456.1 - 0.12 11.1 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DUF374 PF04028.13 KFM25457.1 - 0.093 12.3 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF374) EMC3_TMCO1 PF01956.16 KFM25458.1 - 8.8e-17 61.4 0.0 1.1e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like zf-C3HC4_3 PF13920.6 KFM25459.1 - 3.5e-09 36.4 6.8 7.6e-09 35.3 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM25459.1 - 2.9e-05 24.3 8.2 5.7e-05 23.4 8.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KFM25459.1 - 0.0002 21.1 7.4 0.00036 20.3 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFM25459.1 - 0.00083 19.2 9.9 0.0013 18.5 8.7 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KFM25459.1 - 0.004 17.0 8.5 0.008 16.0 8.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.11 KFM25459.1 - 0.015 15.2 2.3 0.026 14.5 1.0 1.9 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4_4 PF15227.6 KFM25459.1 - 0.018 15.2 7.4 0.043 14.0 7.4 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 KFM25459.1 - 0.078 13.1 3.4 0.21 11.7 3.4 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_UBOX PF13445.6 KFM25459.1 - 0.1 12.6 3.4 0.1 12.7 1.2 2.1 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_4 PF14570.6 KFM25459.1 - 0.5 10.2 6.7 1.1 9.1 6.7 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain CENP-F_leu_zip PF10473.9 KFM25461.1 - 0.01 15.8 5.0 0.01 15.8 5.0 3.3 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ALIX_LYPXL_bnd PF13949.6 KFM25461.1 - 0.013 14.8 18.1 0.023 14.0 18.1 1.4 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV CtIP_N PF10482.9 KFM25461.1 - 0.071 13.2 7.6 0.078 13.0 0.4 2.8 2 1 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain Csm1_N PF18504.1 KFM25461.1 - 0.13 12.6 16.8 1.1 9.7 1.2 4.9 4 1 1 5 5 5 0 Csm1 N-terminal domain Snapin_Pallidin PF14712.6 KFM25461.1 - 0.27 11.7 10.6 0.1 13.0 2.4 3.4 3 0 0 3 3 3 0 Snapin/Pallidin DUF724 PF05266.14 KFM25461.1 - 3.3 7.5 14.7 3.3 7.5 1.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Fez1 PF06818.15 KFM25461.1 - 5.2 7.5 24.8 0.49 10.8 9.1 2.7 2 1 1 3 3 3 0 Fez1 AAA_13 PF13166.6 KFM25461.1 - 5.9 5.4 14.8 64 2.0 13.9 2.1 1 1 0 1 1 1 0 AAA domain Tup_N PF08581.10 KFM25461.1 - 9.1 6.7 9.8 1.5 9.2 4.5 2.5 3 1 0 3 3 3 0 Tup N-terminal Form_Nir_trans PF01226.17 KFM25462.1 - 2.5e-61 207.0 20.2 4.7e-61 206.1 20.2 1.5 1 0 0 1 1 1 1 Formate/nitrite transporter TFCD_C PF12612.8 KFM25462.1 - 5.1e-10 39.5 0.1 1.4e-09 38.0 0.1 1.7 1 0 0 1 1 1 1 Tubulin folding cofactor D C terminal CBM_48 PF02922.18 KFM25462.1 - 9.7e-07 29.1 0.0 1.8e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) SlyX PF04102.12 KFM25462.1 - 0.23 12.1 0.3 2.3 8.9 0.3 2.3 2 0 0 2 2 2 0 SlyX WD40 PF00400.32 KFM25463.1 - 3e-50 167.1 17.3 3.7e-09 37.0 0.4 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM25463.1 - 3.3e-13 49.7 0.0 0.001 19.3 0.0 4.2 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFM25463.1 - 5.1e-08 32.0 0.2 0.14 10.8 0.0 4.1 1 1 2 4 4 4 3 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 KFM25463.1 - 3.5e-05 22.9 3.6 0.13 11.2 0.0 3.7 1 1 3 4 4 4 2 Partner and localizer of BRCA2 WD40 domain Nucleoporin_N PF08801.11 KFM25463.1 - 0.0063 15.3 0.0 0.054 12.2 0.0 2.2 3 0 0 3 3 3 1 Nup133 N terminal like WD40_like PF17005.5 KFM25463.1 - 0.027 13.8 0.0 0.06 12.7 0.0 1.6 1 1 0 1 1 1 0 WD40-like domain eIF2A PF08662.11 KFM25463.1 - 0.031 14.1 0.0 3.2 7.6 0.0 2.8 2 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFM25463.1 - 0.036 13.0 1.8 0.34 9.8 0.3 2.8 1 1 2 4 4 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF5046 PF16465.5 KFM25463.1 - 0.12 11.8 0.0 5.4 6.4 0.0 2.6 1 1 1 3 3 3 0 Domain of unknown function (DUF5046) WD40 PF00400.32 KFM25464.1 - 2.3e-27 94.7 6.0 0.00015 22.5 0.1 6.3 5 1 1 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM25464.1 - 2.8e-07 30.7 0.0 1.9 8.8 0.0 5.8 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFM25464.1 - 0.014 14.4 0.0 5.4 5.9 0.0 2.8 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Fer4 PF00037.27 KFM25465.1 - 1.7e-14 53.0 16.4 1.6e-08 34.0 4.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KFM25465.1 - 3e-13 50.2 10.5 4.8e-13 49.5 10.5 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KFM25465.1 - 1.1e-10 42.3 5.9 5.6e-05 24.0 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 KFM25465.1 - 2.8e-10 40.2 3.4 9.6e-05 22.4 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 KFM25465.1 - 6.2e-09 35.8 21.1 1.9e-06 27.9 12.4 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KFM25465.1 - 1.8e-08 34.4 10.5 3e-08 33.7 10.5 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KFM25465.1 - 3.3e-07 30.1 17.8 0.00037 20.4 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 KFM25465.1 - 8.1e-07 29.4 8.4 0.00054 20.4 0.6 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 KFM25465.1 - 1.1e-06 28.3 12.5 0.0025 17.8 2.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 KFM25465.1 - 4.7e-06 26.7 10.8 0.00027 21.2 1.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 KFM25465.1 - 0.00041 20.8 11.5 0.041 14.4 12.7 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.6 KFM25465.1 - 0.01 16.3 14.6 0.61 10.7 2.6 2.6 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 KFM25465.1 - 0.02 15.1 8.4 0.81 9.9 1.3 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 KFM25465.1 - 0.022 15.0 5.8 0.66 10.3 0.3 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain ETF_QO PF05187.13 KFM25465.1 - 0.062 13.4 5.7 0.23 11.6 0.6 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S EPF PF17181.4 KFM25465.1 - 0.15 12.1 3.3 0.46 10.5 0.5 2.3 2 0 0 2 2 2 0 Epidermal patterning factor proteins Fer4_3 PF12798.7 KFM25465.1 - 0.17 12.9 16.3 0.32 12.0 4.1 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 KFM25465.1 - 0.36 11.7 11.7 3.3 8.6 2.1 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain mTERF PF02536.14 KFM25466.1 - 2e-28 99.3 0.0 2.4e-15 56.3 0.0 2.7 2 1 1 3 3 3 2 mTERF HTH_31 PF13560.6 KFM25466.1 - 0.056 13.8 0.3 0.41 11.0 0.1 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain DUF3606 PF12244.8 KFM25466.1 - 0.082 12.9 0.0 0.24 11.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) Amino_oxidase PF01593.24 KFM25467.1 - 5.6e-53 180.8 9.8 2.1e-52 178.9 9.8 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFM25467.1 - 5.2e-13 49.0 1.0 5.2e-13 49.0 1.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KFM25467.1 - 3.7e-05 23.0 3.0 3.7e-05 23.0 3.0 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KFM25467.1 - 7.2e-05 22.2 0.6 0.00041 19.7 0.4 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFM25467.1 - 0.00025 20.4 1.2 0.00043 19.6 1.2 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KFM25467.1 - 0.00046 19.9 1.6 0.00046 19.9 1.6 2.9 3 1 1 4 4 4 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KFM25467.1 - 0.0011 18.3 0.5 0.0016 17.8 0.5 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KFM25467.1 - 0.0012 18.3 4.3 0.0014 18.1 2.5 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KFM25467.1 - 0.029 14.9 0.4 0.073 13.6 0.4 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFM25467.1 - 0.033 13.4 0.6 0.056 12.7 0.6 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 KFM25467.1 - 0.052 12.2 1.0 0.082 11.6 1.0 1.3 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 KFM25467.1 - 0.055 12.6 1.4 0.082 12.0 1.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KFM25467.1 - 0.11 11.5 2.3 0.13 11.3 0.4 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 KFM25467.1 - 0.14 11.4 0.8 0.3 10.3 0.8 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 KFM25467.1 - 0.77 9.7 3.9 5.3 7.0 0.4 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pkinase_Tyr PF07714.17 KFM25468.1 - 1.9e-48 165.0 0.0 4.7e-48 163.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM25468.1 - 4.1e-44 150.9 0.0 6.1e-44 150.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain GRA6 PF05084.13 KFM25468.1 - 0.028 14.4 0.9 0.049 13.6 0.9 1.3 1 0 0 1 1 1 0 Granule antigen protein (GRA6) DUF4690 PF15756.5 KFM25468.1 - 0.087 13.4 0.5 0.2 12.3 0.5 1.6 1 0 0 1 1 1 0 Small Novel Rich in Cartilage APH PF01636.23 KFM25468.1 - 0.099 12.5 0.4 0.23 11.4 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KFM25469.1 - 5.1e-34 117.7 0.0 3.8e-26 91.9 0.0 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KFM25469.1 - 8.1e-31 107.3 0.0 1.2e-26 93.7 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain APH PF01636.23 KFM25469.1 - 0.0048 16.8 0.1 0.04 13.8 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KFM25471.1 - 4.1e-51 173.7 0.0 1.8e-29 102.8 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KFM25471.1 - 5.9e-51 173.4 0.0 1.9e-29 102.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 KFM25471.1 - 1.2e-05 25.4 0.1 0.15 12.0 0.0 2.5 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KFM25471.1 - 0.00083 18.8 0.0 0.57 9.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.22 KFM25471.1 - 0.027 14.1 0.0 3.5 7.2 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Pkinase_fungal PF17667.1 KFM25471.1 - 0.27 9.9 0.2 12 4.5 0.1 2.1 2 0 0 2 2 2 0 Fungal protein kinase HMGL-like PF00682.19 KFM25472.1 - 2.2e-53 181.5 0.1 2.5e-53 181.3 0.1 1.0 1 0 0 1 1 1 1 HMGL-like HisKA_3 PF07730.13 KFM25472.1 - 0.072 13.6 1.3 0.15 12.6 0.2 2.1 2 0 0 2 2 2 0 Histidine kinase DER1 PF04511.15 KFM25473.1 - 9.1e-58 195.3 8.3 1e-57 195.2 8.3 1.0 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.22 KFM25473.1 - 0.29 11.1 8.5 0.44 10.5 8.5 1.2 1 0 0 1 1 1 0 Rhomboid family Tmemb_14 PF03647.13 KFM25474.1 - 2.6e-21 76.1 9.5 3.2e-21 75.9 9.5 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Lipase_3 PF01764.25 KFM25475.1 - 5.8e-26 91.1 0.0 9.9e-26 90.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KFM25475.1 - 0.0019 18.9 1.8 0.005 17.5 1.8 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.8 KFM25475.1 - 0.19 11.2 0.0 17 4.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) DUF347 PF03988.12 KFM25475.1 - 8.1 6.7 7.0 4.6 7.5 0.4 3.1 3 0 0 3 3 3 0 Repeat of Unknown Function (DUF347) Lipase_3 PF01764.25 KFM25476.1 - 1.3e-29 102.9 0.0 2.1e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KFM25476.1 - 0.017 15.8 0.0 0.038 14.6 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.8 KFM25476.1 - 0.026 14.1 0.1 0.82 9.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 KFM25476.1 - 0.1 11.8 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Lipase_3 PF01764.25 KFM25477.1 - 6e-24 84.5 0.0 1.7e-23 83.1 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KFM25477.1 - 0.0064 17.1 4.2 0.0064 17.1 4.2 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFM25477.1 - 0.035 13.4 0.2 0.48 9.6 0.0 2.4 2 1 1 3 3 3 0 Serine aminopeptidase, S33 Suf PF05843.14 KFM25478.1 - 3.7e-31 109.2 0.0 2.3e-28 100.0 0.0 3.8 2 2 1 4 4 4 1 Suppressor of forked protein (Suf) CD36 PF01130.21 KFM25479.1 - 5.5e-61 206.5 0.0 8.4e-61 205.9 0.0 1.2 1 0 0 1 1 1 1 CD36 family FAD_binding_4 PF01565.23 KFM25481.1 - 1.4e-10 41.1 0.4 3e-09 36.7 0.2 2.3 2 0 0 2 2 2 1 FAD binding domain ALO PF04030.14 KFM25481.1 - 2.3e-08 34.2 0.0 4.1e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase KH_1 PF00013.29 KFM25482.1 - 2.6e-06 27.2 0.1 5e-06 26.3 0.1 1.5 1 0 0 1 1 1 1 KH domain TPR_2 PF07719.17 KFM25482.1 - 1.4e-05 24.8 1.0 0.22 11.7 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFM25482.1 - 0.0014 18.8 3.8 0.03 14.4 0.6 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFM25482.1 - 0.0067 16.2 0.2 0.66 9.9 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFM25482.1 - 0.031 15.1 7.0 4.3 8.4 0.3 4.0 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFM25482.1 - 0.06 13.0 0.0 3.9 7.2 0.0 3.1 4 0 0 4 4 4 0 TPR repeat TPR_16 PF13432.6 KFM25482.1 - 0.22 12.2 5.5 4.1 8.1 0.4 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat Thg1 PF04446.12 KFM25483.1 - 8.2e-48 161.6 0.0 1.2e-47 161.1 0.0 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 KFM25483.1 - 3.3e-40 137.0 0.1 5.8e-40 136.3 0.1 1.4 1 1 0 1 1 1 1 Thg1 C terminal domain Robl_LC7 PF03259.17 KFM25485.1 - 5e-24 83.9 0.2 5.8e-24 83.7 0.2 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 KFM25485.1 - 0.0079 16.1 0.0 0.009 15.9 0.0 1.1 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 MAPKK1_Int PF08923.10 KFM25485.1 - 0.17 11.7 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Mitogen-activated protein kinase kinase 1 interacting Ank_2 PF12796.7 KFM25488.1 - 1.9e-28 98.9 0.6 1.1e-09 38.7 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM25488.1 - 2.2e-27 95.1 4.0 6.1e-06 26.7 0.1 4.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) DHHC PF01529.20 KFM25488.1 - 3.6e-27 95.1 0.1 5.7e-27 94.5 0.1 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase Ank PF00023.30 KFM25488.1 - 9.1e-23 79.7 11.9 6e-05 23.3 0.1 6.6 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 KFM25488.1 - 3.2e-22 76.2 3.5 0.0024 18.2 0.0 6.5 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 KFM25488.1 - 6.3e-20 71.0 10.2 1.2e-05 25.5 0.1 5.3 1 1 5 6 6 6 5 Ankyrin repeats (many copies) COX6B PF02297.17 KFM25489.1 - 1.4e-15 57.3 0.7 1.8e-15 56.9 0.7 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Mem_trans PF03547.18 KFM25489.1 - 0.068 11.6 0.0 0.078 11.4 0.0 1.0 1 0 0 1 1 1 0 Membrane transport protein Pet191_N PF10203.9 KFM25489.1 - 0.17 12.2 2.4 3.2 8.1 2.5 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 tRNA-synt_1 PF00133.22 KFM25490.1 - 1.7e-215 716.9 0.0 2.6e-215 716.2 0.0 1.3 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KFM25490.1 - 9e-20 71.2 0.0 1.7e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KFM25490.1 - 3.4e-13 49.1 0.0 0.00088 18.1 0.0 3.3 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KFM25490.1 - 0.00058 19.3 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DUF1242 PF06842.12 KFM25491.1 - 6.1e-11 41.9 2.2 1.2e-10 41.0 2.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) DNA_methylase PF00145.17 KFM25492.1 - 1.2e-45 156.4 0.0 9e-39 133.7 0.0 2.3 2 1 0 2 2 2 2 C-5 cytosine-specific DNA methylase DNMT1-RFD PF12047.8 KFM25492.1 - 3.4e-35 121.2 0.0 1.2e-21 77.3 0.0 2.8 2 1 0 2 2 2 2 Cytosine specific DNA methyltransferase replication foci domain BAH PF01426.18 KFM25492.1 - 7.8e-09 35.4 0.0 0.0012 18.7 0.0 2.3 2 0 0 2 2 2 2 BAH domain Cupin_8 PF13621.6 KFM25493.1 - 2.2e-25 89.8 0.0 1.1e-23 84.3 0.0 2.2 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 KFM25493.1 - 1.4e-10 41.6 0.0 5.6e-10 39.6 0.0 2.0 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 KFM25493.1 - 7.3e-05 22.4 0.0 0.00012 21.7 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein F-box-like PF12937.7 KFM25493.1 - 0.0059 16.5 0.2 0.013 15.4 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFM25493.1 - 0.038 13.9 0.1 0.24 11.3 0.0 2.1 2 0 0 2 2 2 0 F-box domain HMA PF00403.26 KFM25494.1 - 2.6e-17 63.0 0.9 2.8e-17 62.9 0.9 1.0 1 0 0 1 1 1 1 Heavy-metal-associated domain DUF599 PF04654.12 KFM25495.1 - 1.7e-25 89.7 4.6 2.1e-25 89.4 4.6 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF599 YtpI PF14007.6 KFM25495.1 - 1.5 9.1 4.8 4.1 7.6 0.1 2.9 1 1 2 3 3 3 0 YtpI-like protein TPR_12 PF13424.6 KFM25496.1 - 2.1e-23 82.4 38.6 5.9e-13 48.9 2.6 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 KFM25496.1 - 2.4e-15 55.8 33.7 5.9e-06 26.0 0.2 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KFM25496.1 - 7.6e-08 32.1 9.9 7.6e-08 32.1 9.9 2.9 2 2 0 2 2 2 1 MalT-like TPR region TPR_1 PF00515.28 KFM25496.1 - 3.7e-07 29.7 1.7 1 9.3 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFM25496.1 - 1.8e-06 27.6 6.3 0.55 10.4 0.1 4.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFM25496.1 - 4.9e-05 23.2 0.3 0.64 10.4 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFM25496.1 - 0.00032 20.6 24.1 0.067 13.3 0.6 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_4 PF07721.14 KFM25496.1 - 0.028 15.0 1.3 0.028 15.0 1.3 10.7 10 1 1 11 11 11 0 Tetratricopeptide repeat FAD-oxidase_C PF02913.19 KFM25496.1 - 0.14 11.7 5.3 0.3 10.7 2.5 2.7 2 1 1 3 3 3 0 FAD linked oxidases, C-terminal domain TPR_14 PF13428.6 KFM25496.1 - 0.56 11.2 0.2 0.56 11.2 0.2 8.0 7 3 0 7 7 7 0 Tetratricopeptide repeat PALP PF00291.25 KFM25497.1 - 2.6e-53 181.3 7.9 3.4e-53 181.0 7.9 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme 2-Hacid_dh_C PF02826.19 KFM25498.1 - 1.8e-44 151.3 0.0 2.2e-44 151.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KFM25498.1 - 1.9e-07 31.4 0.0 3.3e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 KFM25498.1 - 0.00076 19.1 0.1 0.0012 18.5 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KFM25498.1 - 0.00093 19.1 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KFM25498.1 - 0.0093 16.5 0.0 0.025 15.1 0.1 1.8 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 KFM25498.1 - 0.012 15.6 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Rad50_zn_hook PF04423.14 KFM25500.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Rad50 zinc hook motif TPR_16 PF13432.6 KFM25500.1 - 0.48 11.1 7.9 0.11 13.1 3.7 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Filament PF00038.21 KFM25501.1 - 0.036 13.7 0.4 0.07 12.7 0.4 1.4 1 0 0 1 1 1 0 Intermediate filament protein IDEAL PF08858.10 KFM25501.1 - 0.17 11.7 1.0 0.29 10.9 0.1 1.8 2 0 0 2 2 2 0 IDEAL domain Lebercilin PF15619.6 KFM25501.1 - 0.22 11.2 0.2 0.36 10.4 0.2 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease RIO1 PF01163.22 KFM25502.1 - 2.6e-69 232.6 0.0 2.6e-69 232.6 0.0 1.5 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 KFM25502.1 - 0.00015 21.2 0.1 0.41 10.0 0.0 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFM25502.1 - 0.00041 20.4 1.0 0.012 15.5 0.9 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFM25502.1 - 0.064 12.0 0.5 0.18 10.5 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase Choline_kinase PF01633.20 KFM25502.1 - 0.095 12.3 0.0 0.41 10.2 0.0 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase Pkinase PF00069.25 KFM25502.1 - 0.12 11.7 0.0 0.12 11.7 0.0 2.1 2 1 0 2 2 2 0 Protein kinase domain eRF1_2 PF03464.15 KFM25503.1 - 2.1e-44 151.0 0.0 3.6e-44 150.3 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KFM25503.1 - 2.6e-36 124.5 0.1 5e-36 123.6 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 KFM25503.1 - 7.8e-19 67.9 0.0 1.4e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 KFM25503.1 - 3.4e-08 33.8 0.1 5.6e-08 33.1 0.1 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 KFM25503.1 - 1.1e-06 29.0 0.0 1.7e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 DUF872 PF05915.12 KFM25504.1 - 0.19 11.9 0.7 0.44 10.7 0.4 1.7 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) SBP PF03110.14 KFM25505.1 - 6.2e-24 84.1 10.9 6.5e-24 84.0 7.1 2.5 2 0 0 2 2 2 1 SBP domain Coatomer_E PF04733.14 KFM25506.1 - 3.6e-72 243.2 0.0 1.4e-45 156.0 0.0 2.0 1 1 1 2 2 2 2 Coatomer epsilon subunit TPR_19 PF14559.6 KFM25506.1 - 8.1e-07 29.5 10.4 1.9e-05 25.1 0.4 3.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFM25506.1 - 1.9e-05 25.1 16.2 0.002 18.8 0.3 4.4 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFM25506.1 - 7.7e-05 22.8 0.1 0.00076 19.7 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFM25506.1 - 0.00016 21.3 0.2 0.0013 18.3 0.0 2.6 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.17 KFM25506.1 - 0.00032 20.6 6.1 0.0042 17.1 0.1 4.4 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFM25506.1 - 0.00052 20.6 0.1 0.00052 20.6 0.1 4.2 2 1 3 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFM25506.1 - 0.0031 17.3 0.2 0.65 9.9 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFM25506.1 - 0.012 15.9 2.8 0.057 13.7 0.1 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFM25506.1 - 0.13 12.3 5.4 0.73 10.0 0.0 4.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 KFM25506.1 - 0.4 10.8 0.1 0.4 10.8 0.1 4.3 5 1 1 6 6 6 0 Tetratricopeptide repeat 3Beta_HSD PF01073.19 KFM25507.1 - 1.7e-54 184.7 0.0 2.2e-54 184.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KFM25507.1 - 1.4e-32 113.1 0.0 1.7e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KFM25507.1 - 6.3e-18 64.9 0.1 8.1e-18 64.5 0.1 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KFM25507.1 - 1.2e-16 61.1 0.2 1.7e-16 60.7 0.2 1.1 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KFM25507.1 - 1.6e-14 54.1 0.3 1.8e-10 40.7 0.3 2.9 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KFM25507.1 - 1.3e-13 50.7 0.1 7.6e-09 35.1 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 KFM25507.1 - 3e-07 29.9 0.7 0.00044 19.5 0.4 2.1 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein KR PF08659.10 KFM25507.1 - 0.0011 18.9 0.1 0.2 11.5 0.0 2.2 2 0 0 2 2 2 1 KR domain Pet100 PF09803.9 KFM25507.1 - 0.0054 17.2 0.1 0.011 16.2 0.1 1.5 1 0 0 1 1 1 1 Pet100 NmrA PF05368.13 KFM25507.1 - 0.025 14.2 0.6 0.1 12.2 0.6 1.8 1 1 0 1 1 1 0 NmrA-like family DUF669 PF05037.13 KFM25507.1 - 0.031 14.4 0.0 0.044 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF669) DUF212 PF02681.14 KFM25509.1 - 5.6e-45 152.6 0.5 6.3e-45 152.4 0.5 1.0 1 0 0 1 1 1 1 Divergent PAP2 family PAP2 PF01569.21 KFM25509.1 - 2.7 7.7 10.0 5.8 6.7 3.4 2.3 2 1 0 2 2 2 0 PAP2 superfamily AAA_34 PF13872.6 KFM25511.1 - 9.7e-124 412.2 0.0 1.8e-123 411.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Helicase_C_4 PF13871.6 KFM25511.1 - 9.4e-96 320.6 0.0 1.6e-95 319.9 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain on Strawberry notch homologue ResIII PF04851.15 KFM25511.1 - 0.032 14.2 0.0 0.068 13.2 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Hydrolase_4 PF12146.8 KFM25512.1 - 1.1e-11 44.4 0.2 6.3e-08 32.2 0.1 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFM25512.1 - 1.2e-07 31.6 0.0 5.8e-05 22.9 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFM25512.1 - 2.1e-06 27.4 0.0 5e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KFM25512.1 - 2.2e-05 25.2 9.4 2.2e-05 25.2 9.4 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family AXE1 PF05448.12 KFM25512.1 - 0.00018 20.3 0.1 0.0024 16.6 0.2 2.4 3 0 0 3 3 3 1 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 KFM25512.1 - 0.00049 20.0 0.2 0.0008 19.3 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.11 KFM25512.1 - 0.0022 18.0 0.0 1.7 8.5 0.0 2.5 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 KFM25512.1 - 0.008 16.0 0.0 0.022 14.6 0.0 1.7 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Esterase PF00756.20 KFM25512.1 - 0.02 14.6 0.0 0.036 13.7 0.0 1.5 1 1 0 1 1 1 0 Putative esterase DLH PF01738.18 KFM25512.1 - 0.031 13.8 0.0 0.82 9.2 0.0 2.7 2 1 0 2 2 2 0 Dienelactone hydrolase family CLP1_P PF16575.5 KFM25513.1 - 7.6e-25 87.8 0.0 1.2e-24 87.1 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop His_biosynth PF00977.21 KFM25514.1 - 1.9e-26 93.0 0.1 2.4e-26 92.6 0.1 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Tubulin_C PF03953.17 KFM25515.1 - 4.2e-51 172.4 0.1 6.6e-51 171.7 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 KFM25515.1 - 4.3e-44 151.1 0.1 1.3e-22 81.0 0.0 2.3 1 1 1 2 2 2 2 Tubulin/FtsZ family, GTPase domain RabGAP-TBC PF00566.18 KFM25516.1 - 1.5e-38 132.7 0.0 1.9e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain TANGO2 PF05742.12 KFM25517.1 - 4.4e-46 158.0 0.0 5e-46 157.8 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 MatE PF01554.18 KFM25518.1 - 1.7e-40 138.4 29.5 1.6e-23 83.1 15.1 3.1 2 1 1 3 3 3 3 MatE Polysacc_synt_C PF14667.6 KFM25518.1 - 9.7e-08 32.2 2.7 9.7e-08 32.2 2.7 4.3 1 1 4 5 5 5 2 Polysaccharide biosynthesis C-terminal domain WD40 PF00400.32 KFM25519.1 - 5.5e-13 49.2 2.5 4e-05 24.3 0.0 5.0 3 1 1 4 4 4 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KFM25519.1 - 0.0054 15.7 0.1 0.17 10.8 0.0 2.4 2 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 KFM25519.1 - 0.012 15.9 0.0 2.3 8.6 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KFM25519.1 - 0.028 14.4 0.9 1.4 8.9 0.0 3.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DUF5018 PF16410.5 KFM25519.1 - 0.067 11.9 0.0 0.098 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5018) SYS1 PF09801.9 KFM25520.1 - 3.8e-34 117.9 12.0 6.3e-19 68.5 1.4 2.0 2 0 0 2 2 2 2 Integral membrane protein S linking to the trans Golgi network Gp_dh_C PF02800.20 KFM25521.1 - 4e-63 211.7 0.0 6.8e-63 211.0 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain tRNA-synt_1 PF00133.22 KFM25521.1 - 1.1e-49 169.2 0.0 1.2e-36 126.1 0.0 4.6 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 KFM25521.1 - 3.9e-47 160.2 0.0 5.8e-47 159.6 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 Gp_dh_N PF00044.24 KFM25521.1 - 4.3e-35 120.1 0.0 8e-35 119.2 0.0 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain tRNA-synt_1g PF09334.11 KFM25521.1 - 5.5e-22 78.1 0.0 2.9e-16 59.2 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KFM25521.1 - 4.8e-15 55.8 0.1 3.7e-14 53.0 0.1 2.1 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KFM25521.1 - 0.063 12.6 0.0 4.4 6.6 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain 2-Hacid_dh_C PF02826.19 KFM25521.1 - 0.14 11.5 0.0 0.3 10.4 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain tRNA-synt_1f PF01921.18 KFM25521.1 - 0.16 10.9 0.0 0.31 9.9 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (K) ESCRT-II PF05871.12 KFM25522.1 - 1.1e-41 142.4 0.0 1.3e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit UCH_1 PF13423.6 KFM25523.1 - 1.7e-34 119.8 0.0 1.2e-24 87.5 0.0 2.1 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 KFM25523.1 - 1.7e-18 67.7 0.0 2.5e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 Exonuclease BRCT PF00533.26 KFM25523.1 - 4.1e-09 36.7 0.0 0.00077 19.8 0.0 2.5 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain UCH PF00443.29 KFM25523.1 - 2.2e-06 27.4 0.0 0.048 13.1 0.0 2.2 1 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase RTT107_BRCT_5 PF16770.5 KFM25523.1 - 3.9e-06 26.7 0.0 1.4e-05 24.8 0.0 1.8 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 KFM25523.1 - 0.0011 18.9 0.0 0.0038 17.1 0.0 1.9 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 KFM25523.1 - 0.012 16.0 0.0 4.6 7.7 0.0 2.4 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain FAD_binding_3 PF01494.19 KFM25524.1 - 1.9e-12 47.1 1.2 6.7e-06 25.6 0.1 2.6 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KFM25524.1 - 3.4e-06 26.5 0.0 8.3e-06 25.2 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFM25524.1 - 2.4e-05 24.1 0.9 0.0028 17.3 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.22 KFM25524.1 - 0.00011 21.4 0.8 0.00017 20.8 0.8 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 KFM25524.1 - 0.00066 18.5 0.4 0.0011 17.8 0.4 1.3 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.12 KFM25524.1 - 0.0019 17.3 1.4 1.2 8.1 0.1 2.4 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 KFM25524.1 - 0.0031 17.7 0.1 0.01 16.1 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KFM25524.1 - 0.021 14.2 0.8 0.036 13.4 0.8 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KFM25524.1 - 0.025 15.1 0.1 0.054 14.1 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KFM25524.1 - 0.072 13.0 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 KFM25524.1 - 0.079 12.9 1.7 3.9 7.4 0.2 3.4 4 0 0 4 4 4 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KFM25524.1 - 0.083 11.7 1.3 2.2 7.0 0.2 2.5 2 1 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.17 KFM25524.1 - 0.11 11.7 0.1 0.22 10.7 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 KFM25524.1 - 0.16 11.2 0.3 0.29 10.3 0.3 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ORMDL PF04061.14 KFM25525.1 - 9.5e-49 164.7 1.0 1.1e-48 164.5 1.0 1.0 1 0 0 1 1 1 1 ORMDL family DUF4083 PF13314.6 KFM25525.1 - 4.6 7.3 6.2 5.8 7.0 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) AAA PF00004.29 KFM25526.1 - 1.5e-29 103.1 0.0 1.9e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFM25526.1 - 4e-07 30.4 0.1 4.1e-06 27.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFM25526.1 - 7.1e-07 29.8 0.0 1.3e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 KFM25526.1 - 8.3e-06 25.5 0.1 0.031 13.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KFM25526.1 - 1.6e-05 25.5 0.0 2.2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFM25526.1 - 0.00024 21.3 0.0 0.00037 20.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 KFM25526.1 - 0.00032 20.7 0.1 0.00089 19.2 0.1 1.7 1 1 0 1 1 1 1 NACHT domain AAA_28 PF13521.6 KFM25526.1 - 0.00061 20.1 0.0 0.001 19.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KFM25526.1 - 0.00085 19.4 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 KFM25526.1 - 0.00087 19.1 0.0 0.0014 18.4 0.0 1.5 1 1 0 1 1 1 1 Cytidylate kinase RuvB_N PF05496.12 KFM25526.1 - 0.0012 18.7 0.0 0.0027 17.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Viral_helicase1 PF01443.18 KFM25526.1 - 0.0015 18.3 0.0 0.0023 17.7 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 KFM25526.1 - 0.0019 18.6 0.0 0.0035 17.7 0.0 1.4 1 0 0 1 1 1 1 RNA helicase TsaE PF02367.17 KFM25526.1 - 0.0023 17.9 0.0 0.0039 17.2 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 KFM25526.1 - 0.0027 17.7 0.3 0.0062 16.5 0.3 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KFM25526.1 - 0.0039 16.9 0.0 0.0081 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFM25526.1 - 0.0051 16.6 0.0 0.0067 16.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KFM25526.1 - 0.0055 16.5 0.0 0.019 14.7 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KFM25526.1 - 0.0056 16.1 0.0 0.012 15.0 0.0 1.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KFM25526.1 - 0.0073 15.8 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF815 PF05673.13 KFM25526.1 - 0.0076 15.4 0.1 0.035 13.3 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF815) TIP49 PF06068.13 KFM25526.1 - 0.0084 15.4 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain Rad17 PF03215.15 KFM25526.1 - 0.0093 15.9 0.4 0.028 14.4 0.4 1.9 1 1 0 1 1 1 1 Rad17 P-loop domain ATPase PF06745.13 KFM25526.1 - 0.014 14.7 0.1 0.36 10.1 0.0 2.1 1 1 1 2 2 2 0 KaiC AAA_2 PF07724.14 KFM25526.1 - 0.018 15.2 0.0 0.027 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) ABC_tran PF00005.27 KFM25526.1 - 0.02 15.4 0.0 0.026 15.0 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_17 PF13207.6 KFM25526.1 - 0.02 15.3 0.0 0.041 14.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 KFM25526.1 - 0.023 14.0 0.0 2.6 7.2 0.0 2.1 1 1 1 2 2 2 0 KAP family P-loop domain AAA_24 PF13479.6 KFM25526.1 - 0.027 14.2 0.1 0.05 13.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KFM25526.1 - 0.034 14.5 0.0 0.11 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 KFM25526.1 - 0.046 13.6 0.0 0.097 12.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 KFM25526.1 - 0.069 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATPase_2 PF01637.18 KFM25526.1 - 0.087 12.7 0.1 3 7.7 0.0 2.1 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea PhoH PF02562.16 KFM25526.1 - 0.094 12.2 0.0 0.21 11.0 0.0 1.4 1 1 0 1 1 1 0 PhoH-like protein AAA_6 PF12774.7 KFM25526.1 - 0.13 11.3 0.0 0.37 9.7 0.0 1.7 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region CPT PF07931.12 KFM25526.1 - 0.13 12.0 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein NTPase_1 PF03266.15 KFM25526.1 - 0.16 11.8 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_13 PF13166.6 KFM25526.1 - 0.25 10.0 0.0 0.32 9.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KFM25526.1 - 0.28 10.4 0.0 0.39 9.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TPR_12 PF13424.6 KFM25528.1 - 5.9e-05 23.3 27.3 0.044 14.1 0.8 4.9 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFM25528.1 - 0.0047 17.0 7.4 14 6.2 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFM25528.1 - 0.49 10.6 17.9 0.061 13.4 1.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFM25528.1 - 5.7 7.0 22.3 3.9 7.5 0.1 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat APG6_N PF17675.1 KFM25529.1 - 0.45 11.0 19.5 0.035 14.6 10.3 3.3 2 2 0 2 2 2 0 Apg6 coiled-coil region DUF707 PF05212.12 KFM25530.1 - 9.7e-07 28.3 0.0 5.8e-05 22.5 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF707) Nucleotid_trans PF03407.16 KFM25531.1 - 5.1e-11 42.9 0.0 2.1e-09 37.6 0.0 2.7 1 1 1 2 2 2 2 Nucleotide-diphospho-sugar transferase RCC1 PF00415.18 KFM25532.1 - 6.7e-49 164.3 20.2 7.1e-16 58.6 1.9 7.3 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFM25532.1 - 2.4e-16 59.0 28.8 6.5e-05 22.6 0.1 6.8 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat DUF4213 PF13938.6 KFM25532.1 - 0.086 13.1 0.5 23 5.3 0.1 2.9 2 1 0 2 2 2 0 Putative heavy-metal chelation Topoisom_bac PF01131.20 KFM25533.1 - 3.7e-100 335.8 0.0 6.1e-100 335.1 0.0 1.3 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 KFM25533.1 - 3.5e-11 43.2 0.0 9.3e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.6 KFM25533.1 - 0.16 12.5 0.0 0.82 10.2 0.0 2.1 3 0 0 3 3 3 0 Toprim domain Cytadhesin_P30 PF07271.11 KFM25533.1 - 1.2 8.6 7.8 1.5 8.3 5.3 2.0 2 0 0 2 2 2 0 Cytadhesin P30/P32 Mito_carr PF00153.27 KFM25534.1 - 1.4e-56 188.4 1.9 8.5e-23 80.1 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Med25_SD1 PF11235.8 KFM25534.1 - 0.0051 17.2 0.0 0.01 16.2 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit 25 synapsin 1 Serine_protease PF18405.1 KFM25534.1 - 0.2 10.8 0.7 9.3 5.3 0.0 2.4 2 1 0 2 2 2 0 Gammaproteobacterial serine protease PP2C PF00481.21 KFM25536.1 - 2.9e-28 99.2 0.0 6e-28 98.2 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KFM25536.1 - 6.5e-09 35.7 0.1 1.4e-08 34.7 0.1 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C SnoaL_2 PF12680.7 KFM25537.1 - 1.1e-07 32.5 0.4 1.4e-07 32.1 0.4 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 KFM25537.1 - 0.00031 20.5 0.1 0.0013 18.5 0.1 1.9 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase LEA_6 PF10714.9 KFM25537.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.6 1 1 0 1 1 1 0 Late embryogenesis abundant protein 18 SnoaL PF07366.12 KFM25538.1 - 9.2e-13 48.1 0.1 1.3e-12 47.6 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KFM25538.1 - 1.6e-08 35.1 0.0 2.5e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain Spectrin_like PF18373.1 KFM25538.1 - 0.13 12.3 0.1 0.69 10.0 0.0 2.0 2 0 0 2 2 2 0 Spectrin like domain HA2 PF04408.23 KFM25539.1 - 6.2e-17 61.9 0.8 3.1e-16 59.6 0.0 2.7 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KFM25539.1 - 9.2e-14 51.7 0.1 8e-13 48.7 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain R3H PF01424.22 KFM25539.1 - 6.1e-13 48.5 0.1 3.3e-12 46.2 0.0 2.3 2 0 0 2 2 2 1 R3H domain OB_NTP_bind PF07717.16 KFM25539.1 - 3.8e-10 40.0 0.0 7.9e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KFM25539.1 - 2.4e-09 37.2 0.0 1.3e-08 34.9 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Ank_4 PF13637.6 KFM25539.1 - 2.3e-05 24.8 1.2 0.00027 21.4 0.1 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM25539.1 - 3.3e-05 24.4 0.1 0.00017 22.1 0.1 2.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFM25539.1 - 0.00019 21.7 0.1 0.00075 19.7 0.1 2.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KFM25539.1 - 0.0011 19.4 2.8 0.0018 18.6 0.1 3.0 3 0 0 3 3 2 1 Ankyrin repeat ATPase PF06745.13 KFM25539.1 - 0.0026 17.2 0.5 0.013 14.8 0.0 2.3 2 0 0 2 2 2 1 KaiC Ank_3 PF13606.6 KFM25539.1 - 0.0029 18.0 0.0 0.017 15.6 0.0 2.5 1 0 0 1 1 1 1 Ankyrin repeat AAA_16 PF13191.6 KFM25539.1 - 0.011 16.1 0.1 0.011 16.1 0.1 5.3 3 1 0 4 4 3 0 AAA ATPase domain Rh5 PF18515.1 KFM25539.1 - 0.016 14.5 0.3 0.027 13.8 0.3 1.2 1 0 0 1 1 1 0 Rh5 coiled-coil domain AAA_22 PF13401.6 KFM25539.1 - 0.18 12.0 0.0 0.18 12.0 0.0 4.8 5 1 0 5 5 5 0 AAA domain Thioredoxin PF00085.20 KFM25540.1 - 5.2e-11 42.5 0.0 5.4e-11 42.4 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KFM25540.1 - 6.4e-05 23.4 0.0 6.7e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain HyaE PF07449.11 KFM25540.1 - 0.0053 16.7 0.0 0.0062 16.5 0.0 1.2 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE OST3_OST6 PF04756.13 KFM25540.1 - 0.0077 15.6 0.0 0.0077 15.6 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family KaiB PF07689.12 KFM25540.1 - 0.018 14.8 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 KaiB domain Sep15_SelM PF08806.11 KFM25540.1 - 0.022 14.9 0.0 0.026 14.7 0.0 1.1 1 0 0 1 1 1 0 Sep15/SelM redox domain Thioredoxin_8 PF13905.6 KFM25540.1 - 0.069 13.5 0.0 0.077 13.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_6 PF13848.6 KFM25540.1 - 0.11 12.4 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain Whi5 PF08528.11 KFM25540.1 - 1.4 8.6 3.6 3.3 7.4 3.6 1.7 1 0 0 1 1 1 0 Whi5 like Cation_efflux PF01545.21 KFM25541.1 - 4.9e-43 147.2 2.6 6.1e-43 146.9 2.6 1.1 1 0 0 1 1 1 1 Cation efflux family SUR7 PF06687.12 KFM25541.1 - 0.0021 17.7 0.9 8.9 5.9 4.7 2.3 2 0 0 2 2 2 2 SUR7/PalI family DEAD PF00270.29 KFM25542.1 - 2e-19 70.0 0.0 8.2e-19 68.0 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM25542.1 - 1.2e-17 64.2 0.0 2.1e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM25542.1 - 0.016 15.2 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Phage-MuB_C PF09077.11 KFM25542.1 - 0.038 13.9 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Mu B transposition protein, C terminal DNA_meth_N PF18284.1 KFM25542.1 - 0.085 12.8 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 DNA methylase N-terminal domain AAA_22 PF13401.6 KFM25542.1 - 0.093 13.0 0.0 2.9 8.2 0.0 2.9 2 1 0 2 2 2 0 AAA domain PPR_2 PF13041.6 KFM25543.1 - 3e-78 257.8 1.9 3.7e-15 55.8 0.0 8.9 2 1 7 9 9 9 8 PPR repeat family PPR PF01535.20 KFM25543.1 - 8.8e-56 182.3 6.7 3.3e-08 33.2 0.0 9.2 9 0 0 9 9 9 8 PPR repeat PPR_1 PF12854.7 KFM25543.1 - 3.4e-55 183.4 0.6 8.2e-10 38.2 0.0 9.4 9 0 0 9 9 9 8 PPR repeat PPR_3 PF13812.6 KFM25543.1 - 6.4e-49 163.9 0.0 4.9e-15 55.4 0.0 5.6 5 1 1 6 6 6 5 Pentatricopeptide repeat domain PPR_long PF17177.4 KFM25543.1 - 6e-26 91.1 0.0 2.8e-14 53.0 0.0 2.4 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP TFIIB_C_1 PF18542.1 KFM25543.1 - 0.0023 17.9 0.1 0.0072 16.3 0.1 1.8 1 0 0 1 1 1 1 Transcription factor IIB C-terminal module 1 TPR_7 PF13176.6 KFM25543.1 - 0.0034 17.3 11.9 5.5 7.2 0.1 7.3 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFM25543.1 - 0.016 15.4 12.6 1 9.7 0.2 6.5 3 1 3 6 6 6 0 Tetratricopeptide repeat MRP-S27 PF10037.9 KFM25543.1 - 0.035 13.0 0.0 0.063 12.1 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 Clathrin PF00637.20 KFM25543.1 - 0.17 11.8 0.0 1.1 9.2 0.0 2.2 2 0 0 2 2 2 0 Region in Clathrin and VPS Cyclin_C PF02984.19 KFM25543.1 - 0.2 11.7 0.0 0.2 11.7 0.0 2.7 3 1 1 4 4 3 0 Cyclin, C-terminal domain HrpB1_HrpK PF09613.10 KFM25543.1 - 4 7.1 9.9 10 5.8 0.0 4.7 3 2 1 5 5 5 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_14 PF13428.6 KFM25543.1 - 9.3 7.4 33.1 13 7.0 0.0 9.6 7 3 4 11 11 8 0 Tetratricopeptide repeat Galactosyl_T PF01762.21 KFM25545.1 - 3e-38 131.6 0.0 3.8e-38 131.3 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 KFM25545.1 - 0.008 15.6 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Fringe-like Glyco_hydro_31 PF01055.26 KFM25547.1 - 1.3e-176 588.2 0.7 2.8e-105 353.1 0.1 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KFM25547.1 - 1.6e-22 79.6 0.5 5.5e-19 68.2 0.1 3.8 3 0 0 3 3 3 1 Galactose mutarotase-like DUF5110 PF17137.4 KFM25547.1 - 1.6e-05 25.0 0.0 3.8e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) Clr2_transil PF16761.5 KFM25547.1 - 0.062 14.1 0.0 32 5.5 0.0 3.0 2 1 0 2 2 2 0 Transcription-silencing protein, cryptic loci regulator Clr2 PEHE PF15275.6 KFM25547.1 - 0.16 12.6 1.2 8.2 7.1 0.1 2.4 2 0 0 2 2 2 0 PEHE domain Hist_deacetyl PF00850.19 KFM25549.1 - 5e-46 157.6 0.0 5.9e-46 157.3 0.0 1.0 1 0 0 1 1 1 1 Histone deacetylase domain B12-binding PF02310.19 KFM25549.1 - 0.12 12.4 0.4 1.1 9.3 0.0 2.3 1 1 1 2 2 2 0 B12 binding domain HA2 PF04408.23 KFM25550.1 - 1.7e-13 50.8 0.9 1.7e-13 50.8 0.9 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KFM25550.1 - 3.7e-11 43.2 0.0 8.1e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KFM25550.1 - 6.9e-09 36.0 0.0 3.1e-08 33.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KFM25550.1 - 0.008 16.5 0.0 0.027 14.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 KFM25550.1 - 0.012 15.4 0.0 0.044 13.6 0.0 1.8 1 1 0 1 1 1 0 DEAD/DEAH box helicase Ribosomal_L12_N PF16320.5 KFM25550.1 - 0.023 14.4 2.0 2.5 7.9 0.9 3.3 2 0 0 2 2 2 0 Ribosomal protein L7/L12 dimerisation domain AAA_25 PF13481.6 KFM25550.1 - 0.029 14.0 0.0 0.083 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KFM25550.1 - 0.067 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 KaiC TsaE PF02367.17 KFM25550.1 - 0.17 11.9 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 KFM25550.1 - 0.21 12.1 0.9 2 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain DnaJ PF00226.31 KFM25551.1 - 1.1e-17 63.8 0.1 3.1e-17 62.4 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain KH_1 PF00013.29 KFM25551.1 - 2.8e-07 30.2 0.1 2.3e-06 27.4 0.1 2.2 1 1 0 1 1 1 1 KH domain DUF1824 PF08854.10 KFM25551.1 - 0.09 12.7 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1824) VIT1 PF01988.19 KFM25551.1 - 3.9 7.3 4.7 1.1 9.0 0.3 2.0 2 0 0 2 2 2 0 VIT family Pentapeptide_2 PF01469.18 KFM25552.1 - 3.1e-08 33.3 38.3 1.8e-05 24.5 15.0 2.1 1 1 1 2 2 2 2 Pentapeptide repeats (8 copies) ORC2 PF04084.14 KFM25553.1 - 4.8e-71 239.4 0.0 5.5e-71 239.2 0.0 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 2 Cu_amine_oxid PF01179.20 KFM25554.1 - 3.8e-87 292.9 0.0 1.2e-73 248.4 0.0 2.1 1 1 1 2 2 2 2 Copper amine oxidase, enzyme domain LRR_4 PF12799.7 KFM25554.1 - 3.4e-05 24.1 7.4 0.028 14.8 0.0 6.2 6 2 2 8 8 8 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFM25554.1 - 0.0049 16.4 0.0 5.7 6.4 0.0 3.3 2 1 1 3 3 3 3 Leucine-rich repeat Cu_amine_oxidN2 PF02727.16 KFM25554.1 - 0.043 14.1 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain LRR_8 PF13855.6 KFM25554.1 - 0.18 11.6 13.6 0.99 9.2 0.1 5.4 5 2 1 6 6 6 0 Leucine rich repeat F-box PF00646.33 KFM25554.1 - 0.19 11.6 2.1 0.28 11.1 0.2 2.4 2 0 0 2 2 2 0 F-box domain Imm32 PF15566.6 KFM25555.1 - 0.048 13.5 0.1 0.08 12.8 0.1 1.3 1 0 0 1 1 1 0 Immunity protein 32 Hamartin PF04388.12 KFM25555.1 - 2.5 6.7 4.8 3 6.4 4.8 1.1 1 0 0 1 1 1 0 Hamartin protein Syntaxin-18_N PF10496.9 KFM25556.1 - 9.4e-13 48.2 0.0 1.9e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 SNARE-complex protein Syntaxin-18 N-terminus ATG16 PF08614.11 KFM25556.1 - 0.31 11.3 9.6 0.7 10.1 0.5 3.1 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) FAD_binding_3 PF01494.19 KFM25557.1 - 6.5e-14 51.9 0.4 1.8e-13 50.5 0.4 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KFM25557.1 - 5.1e-11 42.8 2.4 0.00012 21.8 0.5 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KFM25557.1 - 3.8e-08 32.6 0.8 0.005 15.7 0.1 2.9 3 0 0 3 3 3 2 Tryptophan halogenase NAD_binding_8 PF13450.6 KFM25557.1 - 6.7e-06 26.2 0.1 1.9e-05 24.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KFM25557.1 - 6.3e-05 22.3 0.1 0.00013 21.3 0.1 1.5 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 KFM25557.1 - 6.4e-05 22.2 0.1 9.5e-05 21.6 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KFM25557.1 - 9.8e-05 21.7 0.2 0.0002 20.7 0.2 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFM25557.1 - 0.00016 20.5 0.0 0.00027 19.8 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 KFM25557.1 - 0.00068 18.8 0.0 0.00068 18.8 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 KFM25557.1 - 0.002 17.6 0.1 0.0034 16.8 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.16 KFM25557.1 - 0.028 14.1 0.1 0.049 13.3 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DSPc PF00782.20 KFM25559.1 - 2.5e-07 30.6 0.0 3.9e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain SNARE PF05739.19 KFM25560.1 - 3.9e-12 46.0 0.4 7.5e-12 45.1 0.4 1.5 1 0 0 1 1 1 1 SNARE domain DUF5345 PF17280.2 KFM25560.1 - 0.011 15.7 0.9 0.049 13.6 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5345) Syntaxin PF00804.25 KFM25560.1 - 0.021 14.5 5.8 0.036 13.7 0.6 2.5 2 1 1 3 3 3 0 Syntaxin HrpB2 PF09487.10 KFM25560.1 - 0.063 13.7 1.0 0.12 12.8 0.9 1.6 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB2) AAA_25 PF13481.6 KFM25560.1 - 0.09 12.3 0.4 0.14 11.7 0.4 1.3 1 0 0 1 1 1 0 AAA domain DUF591 PF04569.14 KFM25560.1 - 0.11 12.6 0.0 0.4 10.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function Orf78 PF06024.12 KFM25560.1 - 0.2 12.0 0.6 0.35 11.2 0.6 1.5 1 0 0 1 1 1 0 Orf78 (ac78) DUF2203 PF09969.9 KFM25560.1 - 0.41 11.4 2.1 0.55 11.0 0.5 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) PP2C PF00481.21 KFM25561.1 - 7.4e-21 74.9 0.0 1.7e-20 73.7 0.0 1.5 2 0 0 2 2 2 1 Protein phosphatase 2C Pkinase PF00069.25 KFM25562.1 - 2.3e-23 82.9 0.0 1.2e-16 60.9 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFM25562.1 - 6.2e-10 38.8 0.0 9.7e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFM25562.1 - 0.00022 21.2 0.1 0.00022 21.2 0.1 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 KFM25562.1 - 0.13 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Mpv17_PMP22 PF04117.12 KFM25564.1 - 7.8e-16 58.1 7.0 1.5e-15 57.2 5.1 2.3 2 0 0 2 2 2 1 Mpv17 / PMP22 family ABC_tran PF00005.27 KFM25565.1 - 1.3e-16 61.4 0.0 4.4e-16 59.7 0.0 1.8 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KFM25565.1 - 2.3e-11 44.1 0.4 2.4e-05 24.3 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KFM25565.1 - 0.0012 19.3 0.1 0.0021 18.5 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KFM25565.1 - 0.0019 17.9 0.0 0.0039 16.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 KFM25565.1 - 0.0019 17.8 0.1 0.0051 16.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KFM25565.1 - 0.0024 17.3 0.0 0.98 8.8 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KFM25565.1 - 0.0033 18.0 0.0 0.0063 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KFM25565.1 - 0.0085 16.0 0.0 0.019 14.9 0.0 1.5 2 0 0 2 2 2 1 RsgA GTPase NACHT PF05729.12 KFM25565.1 - 0.037 14.0 0.2 0.21 11.5 0.1 2.0 2 0 0 2 2 2 0 NACHT domain DUF3584 PF12128.8 KFM25565.1 - 0.041 11.4 0.3 0.055 11.0 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_28 PF13521.6 KFM25565.1 - 0.042 14.1 0.1 0.084 13.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KFM25565.1 - 0.046 14.0 0.3 0.14 12.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain DLIC PF05783.11 KFM25565.1 - 0.077 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_30 PF13604.6 KFM25565.1 - 0.077 12.7 0.8 0.18 11.5 0.8 1.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KFM25565.1 - 0.079 13.4 0.2 0.32 11.4 0.2 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KFM25565.1 - 0.084 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Arf PF00025.21 KFM25565.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family PduV-EutP PF10662.9 KFM25565.1 - 0.14 11.9 0.1 0.24 11.1 0.1 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.6 KFM25565.1 - 0.15 12.3 0.0 0.27 11.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 KFM25565.1 - 0.16 10.6 0.0 0.21 10.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KFM25565.1 - 0.16 12.0 0.3 0.51 10.3 0.3 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) cobW PF02492.19 KFM25565.1 - 0.16 11.5 0.1 0.25 10.9 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.22 KFM25565.1 - 0.18 11.4 0.4 0.29 10.7 0.4 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 KFM25565.1 - 0.2 10.9 0.1 0.32 10.2 0.1 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_15 PF13175.6 KFM25565.1 - 0.35 10.5 0.0 0.51 10.0 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain HA2 PF04408.23 KFM25566.1 - 2.7e-22 79.1 0.3 1.6e-21 76.6 0.0 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KFM25566.1 - 2.6e-13 50.3 0.0 8.6e-13 48.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KFM25566.1 - 1.7e-08 34.7 0.0 4.2e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KFM25566.1 - 7.2e-07 29.1 0.1 1.4e-06 28.2 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KFM25566.1 - 1.3e-05 25.5 0.0 3.7e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFM25566.1 - 0.0001 22.1 0.1 0.00025 20.8 0.1 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KFM25566.1 - 0.0073 15.6 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 KFM25566.1 - 0.0083 16.5 0.1 0.019 15.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KFM25566.1 - 0.0091 15.1 0.0 0.024 13.7 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_33 PF13671.6 KFM25566.1 - 0.011 15.9 2.6 0.052 13.7 0.1 2.7 2 1 0 2 2 2 0 AAA domain PhoH PF02562.16 KFM25566.1 - 0.019 14.4 0.0 0.049 13.1 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_7 PF12775.7 KFM25566.1 - 0.022 14.3 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KFM25566.1 - 0.027 14.2 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KFM25566.1 - 0.047 13.0 0.0 0.096 12.0 0.0 1.4 1 0 0 1 1 1 0 KaiC SRP54 PF00448.22 KFM25566.1 - 0.067 12.8 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.14 KFM25566.1 - 0.08 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_14 PF13173.6 KFM25566.1 - 0.095 12.7 0.1 0.57 10.2 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KFM25566.1 - 0.13 12.7 0.0 1.5 9.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KFM25566.1 - 0.14 12.7 0.0 0.39 11.2 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Myosin_head PF00063.21 KFM25566.1 - 0.16 10.1 0.0 0.26 9.4 0.0 1.2 1 0 0 1 1 1 0 Myosin head (motor domain) cobW PF02492.19 KFM25566.1 - 0.55 9.8 2.4 2.3 7.8 0.1 2.7 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain TPT PF03151.16 KFM25567.1 - 1.1e-12 48.0 10.4 1.2e-12 47.8 10.4 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family HAD_2 PF13419.6 KFM25568.1 - 1.4e-05 25.3 0.0 1.7e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 KFM25568.1 - 0.0056 17.1 1.1 0.0097 16.3 1.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Isochorismatase PF00857.20 KFM25569.1 - 8.7e-34 117.2 0.3 1e-33 117.0 0.3 1.1 1 0 0 1 1 1 1 Isochorismatase family Glyco_trans_4_2 PF13477.6 KFM25569.1 - 0.0063 16.5 0.0 0.0089 16.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like DUF434 PF04256.12 KFM25569.1 - 0.042 13.5 0.1 0.092 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF434) Cep57_CLD_2 PF14197.6 KFM25569.1 - 0.19 11.8 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Glyco_transf_64 PF09258.10 KFM25570.1 - 4.6e-47 160.4 0.0 6.3e-47 159.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain BNR_2 PF13088.6 KFM25570.1 - 0.0052 16.1 0.0 0.011 15.1 0.0 1.4 1 1 0 1 1 1 1 BNR repeat-like domain Diphthamide_syn PF01866.17 KFM25571.1 - 1.2e-45 156.3 0.0 2.1e-44 152.2 0.0 2.2 1 1 0 1 1 1 1 Putative diphthamide synthesis protein S4 PF01479.25 KFM25571.1 - 6.8e-10 38.5 0.0 1.3e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 KFM25571.1 - 7.4e-09 36.4 0.9 1.7e-08 35.2 0.9 1.6 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain DUF525 PF04379.14 KFM25572.1 - 4.8e-19 68.4 0.0 6e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 ApaG domain CM_2 PF01817.21 KFM25573.1 - 0.00014 22.2 0.1 0.27 11.6 0.0 2.7 2 1 0 2 2 2 2 Chorismate mutase type II RNA_pol PF00940.19 KFM25575.1 - 1e-149 498.9 0.0 3.1e-137 457.8 0.0 2.7 1 1 1 2 2 2 2 DNA-dependent RNA polymerase RPOL_N PF14700.6 KFM25575.1 - 2.1e-59 201.6 0.0 2.7e-59 201.2 0.0 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal ThiF PF00899.21 KFM25577.1 - 4e-41 141.0 0.2 1.3e-40 139.3 0.0 1.8 2 0 0 2 2 2 1 ThiF family ATG7_N PF16420.5 KFM25577.1 - 1.1e-38 133.5 0.0 9.2e-23 81.3 0.0 2.2 1 1 1 2 2 2 2 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus Shikimate_DH PF01488.20 KFM25577.1 - 0.024 14.7 0.0 0.19 11.8 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 KFM25577.1 - 0.075 12.4 0.0 1.8 7.9 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Peptidase_C15 PF01470.17 KFM25579.1 - 9.9e-18 65.0 0.0 1.2e-17 64.8 0.0 1.1 1 0 0 1 1 1 1 Pyroglutamyl peptidase NinD PF17466.2 KFM25579.1 - 0.14 12.2 0.1 1.4 9.0 0.1 2.5 1 1 0 1 1 1 0 Family of unknown function RWD PF05773.22 KFM25580.1 - 3.8e-19 69.1 0.0 7.8e-10 39.1 0.0 2.2 2 0 0 2 2 2 2 RWD domain IBR PF01485.21 KFM25580.1 - 4.8e-09 36.3 29.3 0.00013 22.1 9.9 3.3 2 1 1 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_5 PF14634.6 KFM25580.1 - 2.7e-06 27.2 2.7 2.7e-06 27.2 2.7 3.6 2 1 1 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFM25580.1 - 3.9e-05 23.6 5.8 3.9e-05 23.6 5.8 2.7 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFM25580.1 - 9.2e-05 22.2 3.1 9.2e-05 22.2 3.1 3.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM25580.1 - 0.00035 20.9 5.2 0.00035 20.9 5.2 3.4 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFM25580.1 - 0.00038 20.2 5.5 0.00038 20.2 5.5 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFM25580.1 - 0.024 14.4 2.4 0.066 13.0 2.4 1.8 1 0 0 1 1 1 0 RING-like zinc finger DPM2 PF07297.12 KFM25581.1 - 1.1e-16 60.9 1.8 1.2e-16 60.7 1.8 1.1 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 KFM25581.1 - 0.02 14.8 5.4 0.023 14.6 5.4 1.1 1 0 0 1 1 1 0 PIG-P DUF3523 PF12037.8 KFM25584.1 - 2.6e-81 272.9 28.1 3.6e-81 272.4 28.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) AAA PF00004.29 KFM25584.1 - 1.9e-24 86.6 0.1 6.1e-24 84.9 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KFM25584.1 - 0.00013 21.8 0.0 0.00035 20.4 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 KFM25584.1 - 0.0016 17.9 0.0 0.0041 16.5 0.0 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KFM25584.1 - 0.0028 18.1 0.0 0.0028 18.1 0.0 3.8 2 2 2 4 4 2 1 AAA ATPase domain ResIII PF04851.15 KFM25584.1 - 0.0045 17.0 7.1 0.51 10.3 6.8 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_5 PF07728.14 KFM25584.1 - 0.0093 16.0 0.1 0.11 12.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KFM25584.1 - 0.019 15.1 0.0 0.019 15.1 0.0 3.1 3 1 0 3 3 1 0 AAA domain AAA_22 PF13401.6 KFM25584.1 - 0.024 14.9 0.0 0.024 14.9 0.0 3.6 3 1 0 3 3 2 0 AAA domain AAA_24 PF13479.6 KFM25584.1 - 0.032 13.9 0.6 0.12 12.0 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_3 PF07726.11 KFM25584.1 - 0.033 14.0 0.0 0.074 12.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 KFM25584.1 - 0.038 14.4 0.1 0.038 14.4 0.1 2.9 2 1 1 3 3 1 0 AAA domain RNA_helicase PF00910.22 KFM25584.1 - 0.099 13.0 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 KFM25584.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 KFM25584.1 - 0.2 12.2 2.3 0.24 11.9 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_lid_3 PF17862.1 KFM25584.1 - 0.4 10.5 2.8 0.37 10.6 0.3 2.4 2 0 0 2 2 2 0 AAA+ lid domain PH_6 PF15406.6 KFM25584.1 - 0.59 10.4 3.8 0.71 10.2 0.0 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain OmpH PF03938.14 KFM25584.1 - 1.8 8.9 45.6 1.6 9.0 28.1 2.4 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) AAA_11 PF13086.6 KFM25584.1 - 2 8.1 0.0 2 8.1 0.0 3.7 3 1 1 4 4 4 0 AAA domain TFIIA PF03153.13 KFM25584.1 - 6.1 6.7 18.0 8.5 6.3 18.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FHA PF00498.26 KFM25585.1 - 3.9e-06 27.1 0.0 8.7e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 FHA domain Rhodanese PF00581.20 KFM25585.1 - 0.016 15.7 0.0 0.028 14.9 0.0 1.4 1 0 0 1 1 1 0 Rhodanese-like domain ARID PF01388.21 KFM25586.1 - 8.9e-12 45.5 0.0 1.4e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.29 KFM25586.1 - 2.8e-06 27.1 5.9 4.7e-06 26.4 5.9 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KFM25586.1 - 0.21 11.8 2.4 0.34 11.2 2.4 1.3 1 0 0 1 1 1 0 PHD-like zinc-binding domain C1_2 PF03107.16 KFM25586.1 - 0.31 11.4 5.2 0.1 13.0 2.3 1.7 2 0 0 2 2 2 0 C1 domain Nop14 PF04147.12 KFM25586.1 - 3.9 5.6 7.9 5.3 5.1 7.9 1.1 1 0 0 1 1 1 0 Nop14-like family Histone PF00125.24 KFM25587.1 - 7e-17 62.0 0.2 8.9e-17 61.7 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFM25587.1 - 0.0068 16.7 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RP-C PF03428.13 KFM25587.1 - 0.11 12.1 0.2 2.1 7.9 0.0 2.0 1 1 1 2 2 2 0 Replication protein C N-terminal domain Histone_H2A_C PF16211.5 KFM25588.1 - 1.1e-19 69.9 1.3 1.9e-19 69.1 1.3 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KFM25588.1 - 4.7e-15 56.1 0.0 5.8e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFM25588.1 - 1.6e-05 25.1 0.0 2.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SecA_SW PF07516.13 KFM25589.1 - 3.2e-05 24.1 0.1 0.0016 18.6 0.0 2.0 2 0 0 2 2 2 2 SecA Wing and Scaffold domain Histone_H2A_C PF16211.5 KFM25590.1 - 6.2e-20 70.6 1.3 9e-20 70.1 1.3 1.3 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KFM25590.1 - 1.9e-11 44.4 0.0 2.2e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFM25590.1 - 0.032 14.5 0.0 0.041 14.2 0.0 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ACT_4 PF13291.6 KFM25590.1 - 0.12 13.0 0.0 0.15 12.7 0.0 1.3 1 1 0 1 1 1 0 ACT domain SecA_DEAD PF07517.14 KFM25591.1 - 3.8e-94 315.2 0.0 5.3e-94 314.7 0.0 1.2 1 0 0 1 1 1 1 SecA DEAD-like domain SecA_PP_bind PF01043.20 KFM25591.1 - 2.6e-18 66.7 0.0 6.1e-18 65.5 0.0 1.7 1 0 0 1 1 1 1 SecA preprotein cross-linking domain SecA_SW PF07516.13 KFM25591.1 - 1.4e-15 57.9 0.0 6.5e-15 55.7 0.0 1.9 1 1 0 1 1 1 1 SecA Wing and Scaffold domain DEAD PF00270.29 KFM25591.1 - 0.15 11.8 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase TAL_effector PF03377.13 KFM25591.1 - 0.98 9.8 4.5 1.2 9.5 0.1 3.4 3 0 0 3 3 3 0 TAL effector repeat Metallophos PF00149.28 KFM25592.1 - 3.5e-10 40.7 0.0 6.6e-10 39.8 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFM25592.1 - 1.9e-09 37.9 0.9 5.4e-08 33.2 0.9 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ABC_tran PF00005.27 KFM25593.1 - 2.6e-15 57.1 0.0 1.3e-14 54.9 0.0 2.0 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KFM25593.1 - 7.3e-08 32.6 0.1 0.0059 16.5 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KFM25593.1 - 0.0024 17.5 0.1 0.0053 16.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KFM25593.1 - 0.004 17.7 0.0 0.0065 17.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KFM25593.1 - 0.0096 15.7 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.6 KFM25593.1 - 0.026 14.7 0.1 0.045 13.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.8 KFM25593.1 - 0.031 11.8 0.1 0.042 11.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PduV-EutP PF10662.9 KFM25593.1 - 0.043 13.6 0.0 0.068 12.9 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FtsK_SpoIIIE PF01580.18 KFM25593.1 - 0.067 12.5 0.1 0.24 10.7 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_15 PF13175.6 KFM25593.1 - 0.073 12.8 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Arf PF00025.21 KFM25593.1 - 0.088 12.3 0.0 0.22 11.0 0.0 1.6 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_28 PF13521.6 KFM25593.1 - 0.093 13.0 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KFM25593.1 - 0.096 12.6 0.2 0.21 11.5 0.2 1.5 1 0 0 1 1 1 0 NACHT domain RsgA_GTPase PF03193.16 KFM25593.1 - 0.11 12.4 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 KFM25593.1 - 0.16 12.5 0.1 0.33 11.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KFM25593.1 - 0.16 12.2 0.0 0.48 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 KFM25593.1 - 0.17 11.5 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 KFM25593.1 - 0.24 10.6 0.1 0.37 10.0 0.1 1.2 1 0 0 1 1 1 0 Zeta toxin Rad17 PF03215.15 KFM25593.1 - 0.26 11.2 0.2 0.48 10.3 0.1 1.4 2 0 0 2 2 1 0 Rad17 P-loop domain AAA_13 PF13166.6 KFM25593.1 - 0.29 9.7 0.0 0.39 9.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain Nfu_N PF08712.11 KFM25594.1 - 3.8e-30 103.8 0.0 6.8e-30 103.0 0.0 1.4 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 KFM25594.1 - 6.2e-27 93.5 0.0 1e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 NifU-like domain DUF1970 PF09301.10 KFM25594.1 - 0.041 14.1 0.0 0.75 10.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1970) DUF2301 PF10063.9 KFM25595.1 - 2.2e-45 154.4 0.7 2.2e-45 154.4 0.7 1.4 2 0 0 2 2 2 1 Uncharacterized integral membrane protein (DUF2301) Herpes_ICP4_C PF03585.14 KFM25595.1 - 0.083 11.6 1.3 0.15 10.7 1.3 1.4 1 0 0 1 1 1 0 Herpesvirus ICP4-like protein C-terminal region Pro_isomerase PF00160.21 KFM25596.1 - 1e-43 149.4 0.0 1.1e-43 149.2 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thymidylat_synt PF00303.19 KFM25597.1 - 9.9e-93 310.1 0.0 1.7e-45 155.3 0.0 2.1 1 1 1 2 2 2 2 Thymidylate synthase DHFR_1 PF00186.19 KFM25597.1 - 1.3e-22 80.3 0.0 2.9e-22 79.1 0.0 1.6 1 1 0 1 1 1 1 Dihydrofolate reductase fn3 PF00041.21 KFM25598.1 - 0.0012 19.2 0.2 0.0026 18.1 0.2 1.6 1 1 0 1 1 1 1 Fibronectin type III domain Big_5 PF13205.6 KFM25598.1 - 0.0042 17.8 2.1 0.0058 17.3 0.9 1.9 2 0 0 2 2 2 1 Bacterial Ig-like domain Herpes_BLLF1 PF05109.13 KFM25599.1 - 4.7 5.1 19.6 4.8 5.0 19.6 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Hydrolase_2 PF07486.12 KFM25600.1 - 0.55 11.1 5.4 0.97 10.3 5.4 1.3 1 0 0 1 1 1 0 Cell Wall Hydrolase Ribosomal_S9 PF00380.19 KFM25600.1 - 0.59 10.7 5.1 0.62 10.6 4.3 1.6 1 1 0 1 1 1 0 Ribosomal protein S9/S16 GTP_cyclohydro2 PF00925.20 KFM25601.1 - 8e-55 184.9 0.0 1.1e-54 184.4 0.0 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase II NYN_YacP PF05991.11 KFM25602.1 - 1.9e-11 44.2 0.0 2.8e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 YacP-like NYN domain Spore_III_AE PF09546.10 KFM25603.1 - 0.033 13.4 0.0 0.052 12.8 0.0 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AE (spore_III_AE) PEX11 PF05648.14 KFM25604.1 - 9.3e-36 123.4 0.9 1.1e-35 123.1 0.9 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) HSP90 PF00183.18 KFM25605.1 - 1.1e-83 281.9 0.2 2.9e-54 184.8 0.0 2.2 1 1 1 2 2 2 2 Hsp90 protein HATPase_c PF02518.26 KFM25605.1 - 5.8e-15 55.8 0.1 1.1e-14 54.8 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KFM25605.1 - 4e-11 42.9 0.0 7.1e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase S1 PF00575.23 KFM25609.1 - 2.1e-38 130.5 2.8 1.9e-19 69.8 0.0 3.2 3 0 0 3 3 3 3 S1 RNA binding domain PCB_OB PF17092.5 KFM25609.1 - 0.0076 17.0 0.2 5.6 7.8 0.0 3.4 2 1 1 3 3 3 1 Penicillin-binding protein OB-like domain DUF2110 PF09883.9 KFM25609.1 - 0.028 14.0 0.1 0.69 9.5 0.0 2.6 2 1 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2110) S1_2 PF13509.6 KFM25609.1 - 0.099 12.7 0.0 13 5.9 0.0 2.8 2 0 0 2 2 2 0 S1 domain TFIIS_M PF07500.14 KFM25610.1 - 1.3e-26 93.2 0.1 2.7e-26 92.2 0.0 1.6 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 KFM25610.1 - 1.3e-19 69.8 7.4 2.4e-19 68.9 7.4 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 KFM25610.1 - 0.00011 22.1 0.0 0.00028 20.8 0.0 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain HEAT_2 PF13646.6 KFM25610.1 - 0.025 15.0 1.3 0.077 13.4 0.9 2.0 2 0 0 2 2 2 0 HEAT repeats zf-DNL PF05180.12 KFM25610.1 - 0.23 11.4 1.7 0.43 10.5 1.7 1.4 1 0 0 1 1 1 0 DNL zinc finger Elf1 PF05129.13 KFM25610.1 - 0.37 10.9 4.9 0.3 11.2 3.2 1.7 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Exo_endo_phos PF03372.23 KFM25611.1 - 2.9e-25 89.2 0.0 4.7e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-C6H2 PF15801.5 KFM25611.1 - 6.1e-07 29.6 4.7 1.2e-06 28.8 4.7 1.5 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KFM25611.1 - 0.02 15.0 7.5 0.037 14.1 7.5 1.4 1 0 0 1 1 1 0 MYND finger zf-MYND PF01753.18 KFM25612.1 - 5.1e-05 23.3 4.5 5.1e-05 23.3 4.5 2.2 3 0 0 3 3 3 1 MYND finger DUF2256 PF10013.9 KFM25612.1 - 2.6 8.2 7.4 50 4.1 7.4 2.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) LRR_6 PF13516.6 KFM25613.1 - 4.3e-22 76.2 23.9 0.32 11.1 0.0 15.2 16 0 0 16 16 16 6 Leucine Rich repeat LRR_4 PF12799.7 KFM25613.1 - 1.9e-19 69.4 8.1 0.35 11.4 0.0 12.1 8 5 7 16 16 16 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFM25613.1 - 2.5e-18 65.6 8.4 0.077 12.8 0.0 9.7 9 1 1 10 10 10 6 Leucine rich repeat LRR_1 PF00560.33 KFM25613.1 - 1.8e-07 30.7 13.9 5.7 7.9 0.1 11.6 14 1 0 14 14 14 2 Leucine Rich Repeat F-box-like PF12937.7 KFM25613.1 - 0.004 17.0 0.4 0.012 15.5 0.4 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFM25613.1 - 0.019 14.8 1.2 0.047 13.6 0.2 2.3 2 0 0 2 2 2 0 F-box domain LRR_9 PF14580.6 KFM25613.1 - 0.082 12.4 0.3 34 3.9 0.1 3.9 4 1 1 5 5 5 0 Leucine-rich repeat LRR_2 PF07723.13 KFM25613.1 - 0.74 10.6 8.0 1.6e+02 3.2 0.0 6.3 6 0 0 6 6 6 0 Leucine Rich Repeat FKBP_C PF00254.28 KFM25614.1 - 2.6e-37 127.0 0.0 3.2e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Kinesin PF00225.23 KFM25615.1 - 6.5e-102 340.9 0.0 8.4e-102 340.5 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFM25615.1 - 1.7e-29 102.7 0.0 2.8e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding CH PF00307.31 KFM25615.1 - 1.8e-09 37.7 0.0 3.4e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFM25615.1 - 0.045 13.6 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 CAMSAP CH domain Utp14 PF04615.13 KFM25617.1 - 7.8e-153 510.8 35.2 7.8e-153 510.8 35.2 1.9 1 1 1 2 2 2 1 Utp14 protein ECH_1 PF00378.20 KFM25618.1 - 4.3e-77 258.8 0.2 4.9e-77 258.6 0.2 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFM25618.1 - 1.2e-38 133.4 0.7 2.2e-38 132.6 0.7 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KFM25618.1 - 0.035 14.0 0.1 0.24 11.4 0.0 2.1 2 0 0 2 2 2 0 Peptidase family S49 BPL_LplA_LipB PF03099.19 KFM25619.1 - 1.3e-11 44.5 0.0 2.1e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF2254 PF10011.9 KFM25619.1 - 0.21 10.4 0.0 0.34 9.7 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) DEAD PF00270.29 KFM25620.1 - 9.9e-38 129.6 0.0 1.5e-37 129.1 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM25620.1 - 4.8e-25 88.1 0.0 8.6e-25 87.2 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM25620.1 - 0.0011 19.0 0.0 0.0016 18.5 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KFM25620.1 - 0.0025 17.0 0.0 0.0038 16.5 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase HAD PF12710.7 KFM25620.1 - 0.031 14.7 0.2 0.37 11.2 0.1 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase FBPase PF00316.20 KFM25621.1 - 5.4e-34 117.3 0.0 1.6e-33 115.8 0.1 1.6 2 0 0 2 2 2 1 Fructose-1-6-bisphosphatase, N-terminal domain DUF2415 PF10313.9 KFM25621.1 - 2.1e-11 43.5 0.1 6.2e-11 42.0 0.1 1.8 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) ANAPC4_WD40 PF12894.7 KFM25621.1 - 2.1e-05 24.7 0.0 0.18 12.1 0.0 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFM25621.1 - 6.3e-05 23.7 4.8 0.069 14.1 0.8 3.6 4 0 0 4 4 4 2 WD domain, G-beta repeat WD40 PF00400.32 KFM25623.1 - 0.00016 22.4 4.3 0.33 11.9 0.1 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat PQQ_2 PF13360.6 KFM25623.1 - 0.0032 17.1 0.1 1.2 8.7 0.0 2.5 2 1 0 2 2 2 2 PQQ-like domain PQQ_3 PF13570.6 KFM25623.1 - 0.047 14.2 0.1 2.3 8.8 0.1 2.8 2 0 0 2 2 2 0 PQQ-like domain DUF359 PF04019.12 KFM25623.1 - 0.083 12.5 0.1 15 5.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF359) E1_DerP2_DerF2 PF02221.15 KFM25624.1 - 3.1e-16 60.0 0.0 3.6e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 KFM25624.1 - 0.013 15.9 0.0 0.017 15.5 0.0 1.3 1 0 0 1 1 1 0 ML-like domain EamA PF00892.20 KFM25625.1 - 5e-14 52.6 13.8 4.5e-09 36.6 4.1 2.1 2 0 0 2 2 2 2 EamA-like transporter family Gly_transf_sug PF04488.15 KFM25626.1 - 2.3e-08 34.5 0.0 4.4e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif MTS PF05175.14 KFM25626.1 - 0.0022 17.6 0.1 0.0045 16.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 KFM25626.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Mannosyl_trans2 PF04188.13 KFM25627.1 - 7.4e-72 243.0 12.6 1.1e-71 242.5 12.6 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) Lactamase_B_2 PF12706.7 KFM25629.1 - 2.4e-09 37.0 0.1 3.4e-09 36.5 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF4597 PF15366.6 KFM25630.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4597) TCR PF03638.15 KFM25631.1 - 1.1e-22 80.1 65.7 2.6e-12 46.8 29.9 2.1 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain TFIIA PF03153.13 KFM25631.1 - 5.3 6.9 8.0 8.1 6.3 8.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cpn60_TCP1 PF00118.24 KFM25632.1 - 1.2e-150 502.4 2.0 4.4e-150 500.6 2.0 1.7 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family MFS_1 PF07690.16 KFM25633.1 - 1.5e-32 112.9 40.9 1.5e-32 112.9 40.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM25633.1 - 0.00017 20.6 10.7 0.00017 20.6 10.7 2.2 2 1 1 3 3 3 1 Sugar (and other) transporter GYF_2 PF14237.6 KFM25636.1 - 0.00076 19.2 1.3 1.6 8.6 0.0 3.4 3 1 1 4 4 4 2 GYF domain 2 Troponin-I_N PF11636.8 KFM25636.1 - 0.16 11.9 0.1 0.16 11.9 0.1 3.5 3 1 0 3 3 3 0 Troponin I residues 1-32 Herpes_DNAp_acc PF04929.12 KFM25636.1 - 0.22 10.5 2.3 0.39 9.6 2.3 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Med7 PF05983.11 KFM25637.1 - 4e-28 98.8 0.4 4.6e-27 95.4 0.4 1.9 1 1 0 1 1 1 1 MED7 protein DSHCT PF08148.12 KFM25638.1 - 3.7e-42 143.8 0.8 8.1e-42 142.7 0.8 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 KFM25638.1 - 2.2e-21 77.0 0.0 3.3e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 KFM25638.1 - 1.4e-14 54.3 0.0 5.2e-14 52.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ADH_zinc_N PF00107.26 KFM25638.1 - 4.8e-10 39.5 0.0 1.2e-09 38.2 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PHD PF00628.29 KFM25638.1 - 2.1e-09 37.1 8.4 2.1e-09 37.1 8.4 2.1 2 0 0 2 2 2 1 PHD-finger ADH_N PF08240.12 KFM25638.1 - 7.4e-09 35.5 0.0 2e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KFM25638.1 - 8.7e-09 36.5 0.1 6.8e-08 33.6 0.0 2.8 2 1 0 2 2 2 1 Zinc-binding dehydrogenase Helicase_C PF00271.31 KFM25638.1 - 0.0008 19.7 0.0 0.0016 18.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-ribbon_3 PF13248.6 KFM25638.1 - 0.028 13.8 1.4 0.22 11.0 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-RING_2 PF13639.6 KFM25638.1 - 1.4 9.3 11.2 6.2 7.2 6.9 2.7 2 0 0 2 2 2 0 Ring finger domain p450 PF00067.22 KFM25640.1 - 1.5e-60 205.3 0.0 2.6e-60 204.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 KFM25640.1 - 2e-50 171.6 0.0 2.9e-50 171.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM25640.1 - 1.1e-32 113.4 0.0 1.8e-32 112.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFM25640.1 - 0.0013 17.6 0.0 0.002 17.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Fra10Ac1 PF09725.9 KFM25641.1 - 2.6e-41 140.6 0.0 3.3e-41 140.3 0.0 1.1 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 LSM PF01423.22 KFM25642.1 - 3e-20 71.7 0.1 4e-20 71.3 0.1 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KFM25642.1 - 0.034 13.8 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 Hfq protein Curto_V2 PF07325.11 KFM25642.1 - 0.12 12.3 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Curtovirus V2 protein HEAT PF02985.22 KFM25643.1 - 3.8e-31 104.5 65.9 0.0021 18.2 0.0 22.8 26 0 0 26 26 20 9 HEAT repeat HEAT_2 PF13646.6 KFM25643.1 - 6.1e-21 74.6 120.2 0.00083 19.7 2.5 19.6 14 4 3 18 18 17 9 HEAT repeats HEAT_EZ PF13513.6 KFM25643.1 - 3.5e-20 72.1 168.8 4e-07 30.4 0.2 27.1 22 8 7 29 29 27 12 HEAT-like repeat CLASP_N PF12348.8 KFM25643.1 - 1.7e-13 50.7 0.0 0.0009 18.9 0.0 5.0 5 1 2 7 7 7 4 CLASP N terminal MMS19_C PF12460.8 KFM25643.1 - 9.9e-12 44.7 8.4 0.00053 19.2 0.0 7.5 6 1 1 7 7 7 3 RNAPII transcription regulator C-terminal ParcG PF10274.9 KFM25643.1 - 1.2e-10 41.8 0.0 0.73 9.9 0.0 6.9 7 1 1 8 8 8 3 Parkin co-regulated protein Cnd1 PF12717.7 KFM25643.1 - 5.6e-09 36.2 0.0 0.085 12.9 0.0 5.7 4 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 UME PF08064.13 KFM25643.1 - 4.3e-06 26.6 0.0 5.3 7.0 0.0 6.8 5 1 1 6 6 6 1 UME (NUC010) domain Vac14_Fab1_bd PF12755.7 KFM25643.1 - 4.6e-06 27.2 0.0 0.19 12.3 0.0 5.4 5 0 0 5 5 4 1 Vacuolar 14 Fab1-binding region Cohesin_HEAT PF12765.7 KFM25643.1 - 0.00021 21.5 6.8 1.4 9.2 0.0 6.7 7 0 0 7 7 7 1 HEAT repeat associated with sister chromatid cohesion IFRD PF05004.13 KFM25643.1 - 0.00039 19.6 4.4 49 2.9 0.0 7.4 8 1 1 9 9 9 0 Interferon-related developmental regulator (IFRD) NUC173 PF08161.12 KFM25643.1 - 0.0032 17.1 0.0 3.7 7.1 0.0 3.5 4 0 0 4 4 4 2 NUC173 domain Dopey_N PF04118.14 KFM25643.1 - 0.0088 15.2 0.0 21 4.1 0.0 4.2 4 1 0 4 4 4 0 Dopey, N-terminal DUF3437 PF11919.8 KFM25643.1 - 0.041 13.8 3.6 13 5.8 0.0 5.4 6 1 1 7 7 6 0 Domain of unknown function (DUF3437) TIP120 PF08623.10 KFM25643.1 - 0.041 13.6 0.0 2 8.2 0.0 3.5 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) Arm PF00514.23 KFM25643.1 - 0.15 12.1 0.0 0.15 12.1 0.0 9.7 11 1 1 12 12 10 0 Armadillo/beta-catenin-like repeat DUF167 PF02594.16 KFM25645.1 - 8.2e-06 25.8 0.0 1.3e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 Histone_H2A_C PF16211.5 KFM25646.1 - 7.9e-19 67.1 1.1 1.4e-18 66.3 1.1 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KFM25646.1 - 5e-15 56.0 0.0 6.9e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFM25646.1 - 1.8e-05 24.9 0.0 2.7e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Mito_carr PF00153.27 KFM25648.1 - 4.6e-44 148.3 1.7 1.3e-21 76.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Apt1 PF10351.9 KFM25649.1 - 3.6e-28 98.7 0.0 4.9e-26 91.6 0.0 2.8 3 1 0 3 3 3 2 Golgi-body localisation protein domain DcpS_C PF11969.8 KFM25649.1 - 1.5e-23 83.5 0.0 3e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 KFM25649.1 - 7.6e-13 49.0 0.0 1.5e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 HIT domain AAA_33 PF13671.6 KFM25649.1 - 1.3e-08 35.1 0.1 5.6e-08 33.1 0.1 2.0 1 0 0 1 1 1 1 AAA domain Fmp27_GFWDK PF10347.9 KFM25649.1 - 6.7e-07 29.5 0.0 1.3e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Rieske PF00355.26 KFM25651.1 - 1.8e-16 59.9 0.1 2.9e-16 59.2 0.1 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain ubiquitin PF00240.23 KFM25652.1 - 4.4e-15 55.2 0.0 3.2e-10 39.6 0.0 2.8 2 1 1 3 3 3 2 Ubiquitin family Rad60-SLD PF11976.8 KFM25652.1 - 2.9e-05 23.8 0.0 0.0013 18.5 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like TUG-UBL1 PF11470.8 KFM25652.1 - 6e-05 23.2 0.0 0.00017 21.7 0.0 1.7 2 0 0 2 2 2 1 TUG ubiquitin-like domain DUF2407 PF10302.9 KFM25652.1 - 0.05 14.2 0.0 1.8 9.2 0.0 2.7 2 1 0 2 2 2 0 DUF2407 ubiquitin-like domain YukD PF08817.10 KFM25652.1 - 0.082 13.6 0.4 1.2 9.9 0.0 2.6 3 0 0 3 3 3 0 WXG100 protein secretion system (Wss), protein YukD RBD PF02196.15 KFM25652.1 - 0.1 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Raf-like Ras-binding domain XisH PF08814.10 KFM25652.1 - 0.22 11.7 0.0 0.35 11.0 0.0 1.3 1 0 0 1 1 1 0 XisH protein Tcf25 PF04910.14 KFM25653.1 - 1.1e-53 182.5 0.0 1.6e-53 182.1 0.0 1.1 1 0 0 1 1 1 1 Transcriptional repressor TCF25 MarR_2 PF12802.7 KFM25653.1 - 0.045 13.6 0.6 0.6 10.0 0.1 3.1 3 0 0 3 3 3 0 MarR family F-box-like PF12937.7 KFM25655.1 - 8.5e-09 35.2 0.2 2.5e-08 33.7 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFM25655.1 - 2.9e-05 23.8 0.1 6.2e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 F-box domain DUF3522 PF12036.8 KFM25656.1 - 0.011 16.0 4.3 0.75 10.0 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3522) Stk19 PF10494.9 KFM25657.1 - 5.2e-22 78.7 0.0 7.8e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 IMS_C PF11799.8 KFM25658.1 - 0.00036 21.2 0.0 0.0005 20.7 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS PF00817.20 KFM25659.1 - 1.1e-32 113.0 0.0 1.5e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 impB/mucB/samB family L51_S25_CI-B8 PF05047.16 KFM25659.1 - 3.1e-08 33.4 0.0 5e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Rhodanese PF00581.20 KFM25660.1 - 1.4e-08 35.2 0.0 1.4e-07 31.9 0.0 2.2 1 1 0 1 1 1 1 Rhodanese-like domain Pyr_redox_3 PF13738.6 KFM25660.1 - 0.17 11.1 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Usp PF00582.26 KFM25661.1 - 4.8e-20 72.5 0.3 1.7e-17 64.3 0.3 2.0 1 1 0 1 1 1 1 Universal stress protein family NT5C PF06941.12 KFM25662.1 - 6.5e-08 32.6 0.1 1.3e-07 31.7 0.0 1.6 2 0 0 2 2 2 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) NIF PF03031.18 KFM25662.1 - 0.00016 21.4 0.0 0.00026 20.8 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.6 KFM25662.1 - 0.042 13.9 0.0 0.06 13.4 0.0 1.2 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase TMP-TENI PF02581.17 KFM25662.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Thiamine monophosphate synthase Agenet PF05641.12 KFM25663.1 - 0.028 14.9 0.0 0.081 13.4 0.0 1.7 1 0 0 1 1 1 0 Agenet domain DUF938 PF06080.12 KFM25664.1 - 7.8e-38 130.3 0.0 8.4e-38 130.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Malic_M PF03949.15 KFM25665.1 - 4.2e-86 288.4 0.1 6.1e-86 287.9 0.1 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KFM25665.1 - 2.3e-68 229.6 0.0 3.7e-68 228.9 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain HA2 PF04408.23 KFM25665.1 - 2.9e-19 69.3 0.0 6.5e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KFM25665.1 - 1.1e-13 51.5 0.0 2.1e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KFM25665.1 - 4.1e-10 39.9 0.0 1.7e-09 37.9 0.0 2.1 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Acyltransferase PF01553.21 KFM25666.1 - 3.8e-14 52.4 0.0 5.9e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Dicistro_VP4 PF11492.8 KFM25666.1 - 0.047 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Cricket paralysis virus, VP4 Ctr PF04145.15 KFM25666.1 - 0.13 12.8 0.0 0.28 11.8 0.0 1.6 1 0 0 1 1 1 0 Ctr copper transporter family Rhodanese PF00581.20 KFM25667.1 - 9.3e-08 32.6 0.1 4.5e-05 23.9 0.0 2.0 1 1 1 2 2 2 2 Rhodanese-like domain HRI1 PF16815.5 KFM25667.1 - 0.065 12.9 0.0 0.067 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein HRI1 DUF676 PF05057.14 KFM25668.1 - 0.071 12.6 0.2 0.28 10.7 0.0 1.8 2 0 0 2 2 2 0 Putative serine esterase (DUF676) FA PF08736.11 KFM25668.1 - 0.2 11.7 0.0 0.36 11.0 0.0 1.3 1 0 0 1 1 1 0 FERM adjacent (FA) Sugar_tr PF00083.24 KFM25669.1 - 3.7e-112 375.5 32.6 4.5e-112 375.2 32.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFM25669.1 - 1.1e-21 77.2 36.0 1.1e-21 77.2 36.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily CLLAC PF15675.5 KFM25669.1 - 4.3 7.0 9.1 18 5.0 2.6 3.1 2 0 0 2 2 2 0 CLLAC-motif containing domain Orn_Arg_deC_N PF02784.16 KFM25670.1 - 1.6e-32 112.8 0.0 9.1e-32 110.4 0.0 1.9 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Arg_decarb_HB PF17810.1 KFM25670.1 - 1.6e-12 47.5 0.0 3.6e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Arginine decarboxylase helical bundle domain TIM PF00121.18 KFM25671.1 - 2.7e-81 272.6 0.0 3.2e-81 272.3 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase ETC_C1_NDUFA5 PF04716.14 KFM25672.1 - 6.5e-18 64.3 0.5 1.3e-17 63.3 0.5 1.5 1 0 0 1 1 1 1 ETC complex I subunit conserved region ATPase_gene1 PF09527.10 KFM25672.1 - 8 6.7 9.0 0.21 11.8 0.8 2.5 3 0 0 3 3 3 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter DUF1995 PF09353.10 KFM25674.1 - 5.3e-16 59.2 0.0 8e-16 58.7 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1995) GHMP_kinases_C PF08544.13 KFM25674.1 - 0.037 14.4 0.1 0.16 12.4 0.0 2.0 2 0 0 2 2 2 0 GHMP kinases C terminal MlaE PF02405.16 KFM25675.1 - 4.3e-72 242.2 15.5 5.7e-72 241.8 15.5 1.1 1 0 0 1 1 1 1 Permease MlaE GTP-bdg_N PF13167.6 KFM25676.1 - 1.5e-27 96.1 0.0 3.3e-27 95.0 0.0 1.6 1 0 0 1 1 1 1 GTP-binding GTPase N-terminal GTP-bdg_M PF16360.5 KFM25676.1 - 5.5e-26 91.0 8.1 1e-25 90.1 8.1 1.5 1 0 0 1 1 1 1 GTP-binding GTPase Middle Region MMR_HSR1 PF01926.23 KFM25676.1 - 5.3e-21 74.8 0.1 9.2e-21 74.1 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KFM25676.1 - 1.7e-05 24.9 0.1 0.0011 19.0 0.0 2.2 1 1 1 2 2 2 1 Dynamin family AAA_16 PF13191.6 KFM25676.1 - 0.00076 19.9 0.4 0.0021 18.5 0.1 1.9 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KFM25676.1 - 0.0019 18.1 0.0 0.0043 17.0 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 KFM25676.1 - 0.0042 16.6 0.1 0.0096 15.5 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KFM25676.1 - 0.021 14.4 0.0 4.2 6.9 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 KFM25676.1 - 0.03 14.8 0.0 0.065 13.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter cobW PF02492.19 KFM25676.1 - 0.11 12.1 1.9 1.9 8.0 0.4 2.4 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain HD_5 PF13487.6 KFM25676.1 - 0.13 12.6 0.0 0.34 11.2 0.0 1.8 1 0 0 1 1 1 0 HD domain SRPRB PF09439.10 KFM25676.1 - 0.17 11.3 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit WD40 PF00400.32 KFM25677.1 - 9.1e-30 102.3 15.5 3.3e-05 24.5 0.1 6.7 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM25677.1 - 5e-14 52.4 0.7 0.0091 16.3 0.0 5.2 1 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFM25677.1 - 0.00016 20.7 2.2 11 4.9 0.0 4.7 2 1 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 KFM25677.1 - 0.081 11.2 0.0 0.22 9.8 0.0 1.8 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz zf-ANAPC11 PF12861.7 KFM25678.1 - 2.7e-33 113.9 7.7 3.1e-33 113.7 7.7 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KFM25678.1 - 7.4e-21 74.2 5.6 1.2e-20 73.5 5.6 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KFM25678.1 - 8.5e-09 35.6 9.4 2e-08 34.4 8.5 1.9 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFM25678.1 - 7.7e-08 32.2 1.5 1.2e-07 31.5 1.5 1.3 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFM25678.1 - 7.1e-07 29.0 1.7 7.1e-07 29.0 1.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFM25678.1 - 7.9e-07 29.0 2.3 1.7e-06 27.9 0.6 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFM25678.1 - 9.1e-06 25.4 1.8 0.00025 20.8 0.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM25678.1 - 1.7e-05 24.6 5.0 3.9e-05 23.4 5.0 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KFM25678.1 - 3.9e-05 23.4 0.8 0.0012 18.6 0.6 2.1 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KFM25678.1 - 0.0003 20.6 1.1 0.0003 20.6 1.1 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 RINGv PF12906.7 KFM25678.1 - 0.00058 19.9 3.3 0.00058 19.9 3.3 2.1 2 0 0 2 2 2 1 RING-variant domain zf-RING-like PF08746.11 KFM25678.1 - 0.0013 19.0 3.1 0.003 17.8 3.1 1.6 1 0 0 1 1 1 1 RING-like domain zf-Nse PF11789.8 KFM25678.1 - 0.0017 18.1 1.5 0.003 17.3 1.5 1.6 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 KFM25678.1 - 0.0019 18.3 1.4 0.0019 18.3 1.4 1.7 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 KFM25678.1 - 0.0032 17.0 2.7 0.0032 17.0 2.7 2.5 2 1 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 KFM25678.1 - 0.0053 16.5 7.3 0.015 15.1 4.3 2.7 2 1 0 2 2 2 1 RING-like zinc finger DUF5318 PF17249.2 KFM25678.1 - 0.027 14.3 0.5 0.16 11.8 0.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5318) zf-P11 PF03854.14 KFM25678.1 - 0.053 13.2 4.0 1 9.1 0.9 2.2 2 0 0 2 2 2 0 P-11 zinc finger FANCL_C PF11793.8 KFM25678.1 - 0.35 11.1 8.9 2.4 8.4 8.9 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 KFM25678.1 - 0.52 10.2 6.9 1.8 8.5 7.0 2.0 1 1 0 1 1 1 0 PHD-finger zf-C3H2C3 PF17122.5 KFM25678.1 - 7.1 6.8 8.7 3.7 7.6 4.1 2.6 2 1 0 2 2 2 0 Zinc-finger Heme_oxygenase PF01126.20 KFM25680.1 - 5.4e-10 39.4 0.0 6.9e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Heme oxygenase NUDIX PF00293.28 KFM25682.1 - 4.7e-20 72.0 0.1 8.5e-20 71.1 0.1 1.4 1 1 0 1 1 1 1 NUDIX domain Myosin_head PF00063.21 KFM25684.1 - 3e-209 696.6 0.0 4.1e-184 613.6 0.0 2.1 1 1 1 2 2 2 2 Myosin head (motor domain) DIL PF01843.19 KFM25684.1 - 1.4e-05 25.3 0.0 3.6e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 DIL domain AAA_22 PF13401.6 KFM25684.1 - 0.0081 16.4 0.0 0.062 13.6 0.0 2.6 1 0 0 1 1 1 1 AAA domain Hpr_kinase_C PF07475.12 KFM25684.1 - 0.021 14.4 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Zeta_toxin PF06414.12 KFM25684.1 - 0.038 13.3 0.1 0.11 11.7 0.1 1.8 1 0 0 1 1 1 0 Zeta toxin Sigma54_activat PF00158.26 KFM25684.1 - 0.059 13.1 0.1 0.14 11.8 0.1 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.6 KFM25684.1 - 0.071 13.5 0.0 0.071 13.5 0.0 4.7 5 1 0 5 5 5 0 AAA ATPase domain Peptidase_S46 PF10459.9 KFM25684.1 - 0.72 8.4 3.9 1.1 7.8 3.9 1.1 1 0 0 1 1 1 0 Peptidase S46 ATG16 PF08614.11 KFM25684.1 - 2.4 8.3 15.9 4.3 7.5 15.9 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 KFM25684.1 - 7.8 5.3 9.6 13 4.6 9.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Peptidase_M20 PF01546.28 KFM25685.1 - 2.5e-19 69.8 0.0 7.8e-15 55.1 0.0 3.1 2 1 0 2 2 2 2 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 KFM25685.1 - 0.091 12.4 0.1 0.33 10.6 0.1 1.8 1 1 0 1 1 1 0 Peptidase family M28 ATE_C PF04377.15 KFM25686.1 - 8.4e-31 107.4 1.4 8.3e-30 104.2 1.4 2.3 1 1 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 KFM25686.1 - 4.9e-24 84.5 1.6 1e-23 83.5 1.6 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus CBS PF00571.28 KFM25687.1 - 5.8e-24 84.3 2.1 2.6e-07 31.0 0.0 4.9 5 0 0 5 5 5 4 CBS domain SnoaL_3 PF13474.6 KFM25688.1 - 9.7e-23 80.7 0.1 1.3e-22 80.3 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain UVR PF02151.19 KFM25688.1 - 1.9e-06 27.4 1.5 3.1e-06 26.7 1.5 1.3 1 0 0 1 1 1 1 UvrB/uvrC motif DUF4440 PF14534.6 KFM25688.1 - 0.00019 21.8 0.9 0.00044 20.6 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 KFM25688.1 - 0.00037 21.1 0.1 0.00065 20.3 0.1 1.4 1 0 0 1 1 1 1 SnoaL-like domain LEH PF07858.12 KFM25688.1 - 0.14 12.3 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Limonene-1,2-epoxide hydrolase catalytic domain CaMKII_AD PF08332.10 KFM25688.1 - 0.18 12.0 0.1 0.29 11.3 0.1 1.4 1 0 0 1 1 1 0 Calcium/calmodulin dependent protein kinase II association domain Tetraspanin PF00335.20 KFM25689.1 - 0.00066 19.5 0.3 0.001 18.9 0.1 1.4 1 1 0 1 1 1 1 Tetraspanin family WD40 PF00400.32 KFM25690.1 - 4.7e-19 68.4 11.9 8e-07 29.7 0.2 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM25690.1 - 2.2e-06 27.8 0.0 0.37 11.1 0.0 5.0 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFM25690.1 - 0.25 10.2 0.1 1e+02 1.7 0.0 3.7 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein MFS_5 PF05631.14 KFM25691.1 - 3.8e-142 473.4 13.8 5.1e-142 473.0 13.8 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 KFM25691.1 - 1.2e-22 80.4 28.1 1.2e-22 80.4 28.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM25691.1 - 4.2e-07 29.2 2.4 4.2e-07 29.2 2.4 3.6 1 1 3 4 4 4 2 Sugar (and other) transporter IPPT PF01715.17 KFM25692.1 - 1.1e-37 130.1 0.0 2e-22 80.2 0.0 2.1 1 1 1 2 2 2 2 IPP transferase IPT PF01745.16 KFM25692.1 - 1.8e-08 34.0 0.0 2.9e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Isopentenyl transferase AAA_33 PF13671.6 KFM25692.1 - 0.0005 20.2 0.0 0.0012 19.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFM25692.1 - 0.0076 16.6 0.1 0.017 15.5 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 KFM25692.1 - 0.049 14.2 0.0 0.13 12.8 0.0 1.9 2 1 0 3 3 3 0 AAA domain Hydin_ADK PF17213.3 KFM25692.1 - 0.091 13.0 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Zeta_toxin PF06414.12 KFM25692.1 - 0.18 11.1 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin CoA_binding PF02629.19 KFM25693.1 - 7.9e-31 106.6 0.7 7.9e-31 106.6 0.7 1.9 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 KFM25693.1 - 4.5e-22 78.5 0.4 8.2e-22 77.7 0.4 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KFM25693.1 - 7.9e-11 41.9 0.1 1.6e-10 40.9 0.1 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KFM25693.1 - 0.0011 19.4 0.0 0.0032 17.9 0.0 1.7 2 0 0 2 2 2 1 CoA binding domain Voldacs PF03517.13 KFM25694.1 - 3.3e-16 59.7 0.1 6.4e-16 58.7 0.0 1.5 2 0 0 2 2 2 1 Regulator of volume decrease after cellular swelling PH_TFIIH PF08567.11 KFM25694.1 - 0.034 14.5 0.0 0.052 13.9 0.0 1.2 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain Pentapeptide_2 PF01469.18 KFM25696.1 - 7e-11 41.8 31.5 8.4e-06 25.6 16.4 2.4 2 0 0 2 2 2 2 Pentapeptide repeats (8 copies) SET PF00856.28 KFM25697.1 - 9.4e-10 39.1 0.0 1.2e-09 38.8 0.0 1.2 1 0 0 1 1 1 1 SET domain Lipase_GDSL_2 PF13472.6 KFM25698.1 - 1.8e-15 57.8 0.1 4.1e-15 56.6 0.0 1.5 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFM25698.1 - 8.2e-10 39.0 0.0 1.1e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TMF_DNA_bd PF12329.8 KFM25700.1 - 9.1e-17 60.8 8.5 9.1e-17 60.8 8.5 4.9 4 0 0 4 4 4 2 TATA element modulatory factor 1 DNA binding TMF_TATA_bd PF12325.8 KFM25700.1 - 1.9e-05 24.9 1.9 1.9e-05 24.9 1.9 5.0 1 1 3 4 4 4 2 TATA element modulatory factor 1 TATA binding PKcGMP_CC PF16808.5 KFM25700.1 - 0.042 13.7 5.6 3.6 7.5 0.5 3.6 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Pkinase_Tyr PF07714.17 KFM25701.1 - 1.4e-38 132.6 0.0 7.2e-38 130.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM25701.1 - 5.8e-36 124.2 0.0 2e-35 122.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain VSP PF03302.13 KFM25701.1 - 0.0021 17.0 0.1 0.003 16.5 0.1 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF4690 PF15756.5 KFM25701.1 - 0.1 13.2 0.7 0.21 12.2 0.7 1.4 1 0 0 1 1 1 0 Small Novel Rich in Cartilage APH PF01636.23 KFM25701.1 - 0.18 11.7 0.2 1.4 8.7 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Podoplanin PF05808.11 KFM25701.1 - 0.43 10.7 3.4 0.8 9.8 3.4 1.3 1 0 0 1 1 1 0 Podoplanin GDC-P PF02347.16 KFM25702.1 - 1.4e-177 590.9 0.0 1.9e-167 557.5 0.0 2.8 3 0 0 3 3 3 2 Glycine cleavage system P-protein FKBP_C PF00254.28 KFM25702.1 - 7.5e-10 39.0 0.0 1.4e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Beta_elim_lyase PF01212.21 KFM25702.1 - 1.9e-05 24.1 0.4 4.5e-05 22.9 0.4 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KFM25702.1 - 6.2e-05 22.1 0.3 0.00053 19.0 0.1 2.5 3 0 0 3 3 3 1 Aminotransferase class-V OAR PF03826.17 KFM25702.1 - 0.024 14.5 1.9 0.067 13.0 1.9 1.8 1 0 0 1 1 1 0 OAR domain CotH PF08757.11 KFM25703.1 - 1.9e-34 119.7 0.0 2.5e-34 119.2 0.0 1.2 1 0 0 1 1 1 1 CotH kinase protein CotH PF08757.11 KFM25704.1 - 1.4e-37 130.0 0.2 2.3e-37 129.2 0.2 1.3 1 1 0 1 1 1 1 CotH kinase protein DrrA_P4M PF14860.6 KFM25705.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 DrrA phosphatidylinositol 4-phosphate binding domain rRNA_methylase PF06962.12 KFM25707.1 - 1.3e-29 102.9 0.0 2.1e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 Putative rRNA methylase AMPK1_CBM PF16561.5 KFM25707.1 - 8.8e-11 41.9 0.0 1.6e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Methyltransf_25 PF13649.6 KFM25707.1 - 1.6e-09 38.3 0.0 5.1e-09 36.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM25707.1 - 7.5e-08 32.3 0.0 1.1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFM25707.1 - 2.7e-07 30.2 0.0 5e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KFM25707.1 - 0.00039 21.0 0.0 0.0018 18.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KFM25707.1 - 0.0035 17.1 0.0 0.0056 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 KFM25707.1 - 0.0044 16.9 0.0 0.019 14.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM25707.1 - 0.032 15.0 0.1 0.14 12.9 0.0 2.1 3 0 0 3 3 2 0 Methyltransferase domain Methyltransf_5 PF01795.19 KFM25707.1 - 0.041 13.4 0.0 0.56 9.6 0.0 2.2 2 0 0 2 2 2 0 MraW methylase family DSPc PF00782.20 KFM25707.1 - 0.15 11.9 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Ubiq_cyt_C_chap PF03981.12 KFM25708.1 - 1.4e-24 86.7 0.7 3.2e-24 85.6 0.7 1.5 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone NCE101 PF11654.8 KFM25708.1 - 0.16 11.7 0.1 22 4.9 0.0 2.7 2 0 0 2 2 2 0 Non-classical export protein 1 DUF4381 PF14316.6 KFM25708.1 - 8.7 6.6 9.1 6.9 6.9 0.2 3.1 3 2 0 3 3 3 0 Domain of unknown function (DUF4381) G-patch PF01585.23 KFM25709.1 - 9.3e-11 41.5 7.2 9.3e-11 41.5 7.2 1.9 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 KFM25709.1 - 5.6e-05 23.2 2.8 5.6e-05 23.2 2.8 2.0 2 0 0 2 2 2 1 G-patch domain CAF1A PF12253.8 KFM25710.1 - 2.5e-11 43.6 0.1 2.5e-11 43.6 0.1 2.1 2 0 0 2 2 2 1 Chromatin assembly factor 1 subunit A AAA_11 PF13086.6 KFM25710.1 - 0.19 11.5 8.4 0.3 10.8 8.4 1.2 1 0 0 1 1 1 0 AAA domain DUF572 PF04502.13 KFM25710.1 - 0.37 10.4 9.7 0.6 9.7 9.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF737 PF05300.11 KFM25710.1 - 1.2 9.5 19.0 2.6 8.3 19.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF737) Rrn6 PF10214.9 KFM25710.1 - 8.3 4.8 6.0 11 4.3 6.0 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor CUE PF02845.16 KFM25711.1 - 9.2e-06 25.3 0.0 2.2e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 CUE domain DSHCT PF08148.12 KFM25713.1 - 1.2e-24 86.8 0.5 3.7e-24 85.2 0.1 1.9 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 KFM25713.1 - 8e-15 55.0 0.0 1.4e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KFM25713.1 - 3e-10 40.4 0.0 4.3e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 KFM25713.1 - 0.00026 20.8 0.0 0.0016 18.2 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein Helicase_C PF00271.31 KFM25713.1 - 0.00047 20.5 0.0 0.0011 19.2 0.0 1.6 2 0 0 2 2 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 KFM25713.1 - 0.0013 19.1 0.1 0.0042 17.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFM25713.1 - 0.006 17.0 0.0 0.006 17.0 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KFM25713.1 - 0.023 14.9 0.0 0.089 13.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 KFM25713.1 - 0.057 12.5 0.0 0.095 11.7 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 KFM25713.1 - 0.072 12.8 0.1 0.072 12.8 0.1 2.7 3 1 0 3 3 3 0 AAA domain PhoH PF02562.16 KFM25713.1 - 0.13 11.7 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein ATPase_2 PF01637.18 KFM25713.1 - 0.19 11.6 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Pet191_N PF10203.9 KFM25714.1 - 8.7e-17 61.2 3.6 1e-16 60.9 3.6 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 HgmA PF04209.13 KFM25715.1 - 1.7e-148 494.8 0.1 2e-148 494.7 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Cellulase PF00150.18 KFM25716.1 - 4.4e-13 49.3 0.7 8.8e-13 48.3 0.7 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 KFM25716.1 - 0.0007 18.8 0.1 0.0019 17.4 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Asp1 PF16993.5 KFM25716.1 - 0.009 15.3 0.0 0.011 15.0 0.0 1.1 1 0 0 1 1 1 1 Accessory Sec system protein Asp1 BCNT PF07572.12 KFM25716.1 - 0.07 13.2 2.9 0.51 10.4 0.4 2.6 1 1 1 2 2 2 0 Bucentaur or craniofacial development Cellsynth_D PF03500.13 KFM25717.1 - 0.14 12.0 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Cellulose synthase subunit D Eapp_C PF10238.9 KFM25719.1 - 3.7e-32 111.5 3.2 3.4e-31 108.3 3.2 2.1 1 1 0 1 1 1 1 E2F-associated phosphoprotein CpXC PF14353.6 KFM25719.1 - 0.019 15.0 0.9 1.3 9.1 0.0 2.2 2 0 0 2 2 2 0 CpXC protein IBR PF01485.21 KFM25719.1 - 0.043 14.0 7.8 0.19 12.0 5.5 2.3 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain zf-CSL PF05207.13 KFM25719.1 - 6 6.7 8.4 0.88 9.3 0.2 2.7 2 1 1 3 3 3 0 CSL zinc finger Rhodanese PF00581.20 KFM25721.1 - 7.1e-06 26.5 0.3 1.8e-05 25.2 0.0 1.9 2 1 0 2 2 2 1 Rhodanese-like domain DUF5610 PF18433.1 KFM25721.1 - 0.032 14.7 0.0 0.073 13.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5610) Antimicrobial_2 PF08023.12 KFM25721.1 - 0.089 13.3 0.2 0.36 11.4 0.2 2.1 1 0 0 1 1 1 0 Frog antimicrobial peptide DUF1517 PF07466.11 KFM25723.1 - 7.9e-62 208.7 0.0 9.7e-62 208.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1517) TrmO PF01980.16 KFM25724.1 - 1e-34 119.3 0.0 1.5e-34 118.8 0.0 1.1 1 0 0 1 1 1 1 tRNA-methyltransferase O DUF1802 PF08819.11 KFM25725.1 - 3.1e-32 111.8 0.0 3.9e-32 111.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1802) Glyco_trans_4_4 PF13579.6 KFM25726.1 - 5.2e-07 30.2 5.0 5.9e-07 30.1 5.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 KFM25726.1 - 0.0014 18.6 0.5 0.0017 18.4 0.5 1.1 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KFM25727.1 - 3.3e-08 34.0 0.0 4.6e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KFM25727.1 - 2.5e-06 27.1 0.0 3.3e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KFM25727.1 - 0.014 15.8 0.0 0.03 14.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 ECH_1 PF00378.20 KFM25728.1 - 6.1e-43 146.9 0.0 7.9e-43 146.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFM25728.1 - 6.6e-26 91.6 0.0 7.8e-26 91.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase PPR_2 PF13041.6 KFM25729.1 - 8e-18 64.4 0.0 1.1e-07 31.9 0.0 5.1 5 0 0 5 5 5 2 PPR repeat family PPR_3 PF13812.6 KFM25729.1 - 3e-14 52.8 0.0 0.00094 19.2 0.0 5.8 4 2 1 5 5 5 3 Pentatricopeptide repeat domain PPR PF01535.20 KFM25729.1 - 2.2e-10 40.1 0.0 0.091 13.0 0.0 6.8 7 0 0 7 7 7 2 PPR repeat PPR_long PF17177.4 KFM25729.1 - 9.2e-10 38.2 5.7 0.013 14.8 0.1 4.6 2 2 2 4 4 4 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 KFM25729.1 - 2.1e-08 33.7 0.0 0.17 11.6 0.0 5.5 6 0 0 6 6 6 3 PPR repeat NRDE-2 PF08424.10 KFM25731.1 - 9.8e-45 153.1 0.1 1.4e-44 152.6 0.1 1.1 1 0 0 1 1 1 1 NRDE-2, necessary for RNA interference Ribosomal_S17e PF00833.18 KFM25732.1 - 1.2e-61 206.0 0.5 1.4e-61 205.8 0.5 1.0 1 0 0 1 1 1 1 Ribosomal S17 DUF2849 PF11011.8 KFM25733.1 - 8.2 7.2 6.3 21 5.9 0.0 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2849) E1-E2_ATPase PF00122.20 KFM25734.1 - 3.5e-22 78.8 0.3 2.9e-21 75.8 0.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KFM25734.1 - 4.2e-16 59.9 2.5 1.2e-09 38.8 0.2 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFM25734.1 - 1e-05 25.5 0.0 2.4e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) ANAPC1 PF12859.7 KFM25735.1 - 0.00032 21.3 0.0 0.00044 20.8 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 ACBP PF00887.19 KFM25736.1 - 2e-24 85.6 0.3 2.4e-24 85.3 0.3 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein PC_rep PF01851.22 KFM25737.1 - 2.8e-06 27.5 27.2 0.043 14.3 1.5 6.8 6 0 0 6 6 6 4 Proteasome/cyclosome repeat ArfGap PF01412.18 KFM25738.1 - 0.00057 19.9 0.0 0.00095 19.2 0.0 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf WD40 PF00400.32 KFM25739.1 - 1.5e-13 51.0 0.1 0.9 10.5 0.0 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM25739.1 - 7.2e-11 42.2 0.0 0.0054 17.0 0.0 5.3 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFM25739.1 - 0.0015 17.6 0.1 13 4.7 0.0 4.4 4 1 1 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KFM25739.1 - 0.02 13.4 0.0 0.064 11.8 0.0 1.8 2 0 0 2 2 2 0 Cytochrome D1 heme domain PD40 PF07676.12 KFM25739.1 - 0.06 13.3 0.5 0.76 9.8 0.0 2.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat PALB2_WD40 PF16756.5 KFM25739.1 - 0.068 12.1 0.0 0.099 11.5 0.0 1.2 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain Glyco_hydro_38N PF01074.22 KFM25740.1 - 5.5e-74 249.1 1.1 8.2e-74 248.6 1.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KFM25740.1 - 5.6e-35 121.4 0.0 1.3e-34 120.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KFM25740.1 - 1e-20 73.7 0.1 2.5e-20 72.4 0.1 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain Enkurin PF13864.6 KFM25741.1 - 7.4e-15 55.2 0.5 8.9e-15 54.9 0.5 1.1 1 0 0 1 1 1 1 Calmodulin-binding Aminotran_1_2 PF00155.21 KFM25742.1 - 5.8e-40 137.6 0.0 8.5e-40 137.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 KFM25742.1 - 1e-06 27.9 0.0 0.00012 21.1 0.0 2.2 1 1 0 1 1 1 1 Allinase TAF4 PF05236.14 KFM25743.1 - 7.1e-16 58.8 9.3 2.8e-14 53.6 9.3 2.2 1 1 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family Rab5-bind PF09311.11 KFM25744.1 - 0.014 14.8 6.4 0.017 14.5 6.4 1.1 1 0 0 1 1 1 0 Rabaptin-like protein BLOC1_2 PF10046.9 KFM25744.1 - 0.043 14.1 3.1 0.073 13.4 2.9 1.5 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF5610 PF18433.1 KFM25744.1 - 0.053 14.0 1.6 0.088 13.3 1.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5610) Spc7 PF08317.11 KFM25744.1 - 0.084 11.7 6.8 0.11 11.4 6.8 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein V-ATPase_G PF03179.15 KFM25744.1 - 0.51 10.9 10.7 0.095 13.2 6.8 1.7 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit UPF0242 PF06785.11 KFM25744.1 - 0.67 10.0 6.0 0.78 9.8 6.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PspB PF06667.12 KFM25744.1 - 1.3 9.1 5.5 3.5 7.7 5.4 1.9 1 1 0 1 1 1 0 Phage shock protein B Nipped-B_C PF12830.7 KFM25747.1 - 8.9e-08 32.3 0.0 1.7e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Sister chromatid cohesion C-terminus Peptidase_C12 PF01088.21 KFM25749.1 - 1.4e-66 224.3 0.0 1.8e-66 223.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KFM25749.1 - 5.1e-11 42.3 0.0 9e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Pkinase PF00069.25 KFM25750.1 - 2.8e-37 128.5 0.0 1.7e-20 73.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFM25750.1 - 0.00032 20.1 0.0 0.02 14.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Ribosomal_L7Ae PF01248.26 KFM25751.1 - 1.9e-25 88.4 0.7 2.3e-25 88.2 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family T2SSM PF04612.12 KFM25751.1 - 0.04 14.0 0.1 0.052 13.6 0.1 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M CN_hydrolase PF00795.22 KFM25752.1 - 7e-51 173.1 0.0 3.4e-42 144.6 0.0 2.0 1 1 1 2 2 2 2 Carbon-nitrogen hydrolase WD40 PF00400.32 KFM25753.1 - 5e-05 24.0 0.0 0.002 18.9 0.0 3.3 3 0 0 3 3 3 1 WD domain, G-beta repeat Sas10 PF09368.10 KFM25754.1 - 2.2e-23 82.5 2.3 2.2e-23 82.5 2.3 2.0 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 KFM25754.1 - 2.3e-17 63.4 0.0 5.7e-17 62.1 0.0 1.7 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Pkinase PF00069.25 KFM25755.1 - 7.1e-71 238.6 0.0 9.1e-71 238.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM25755.1 - 2.6e-34 118.7 0.0 3.3e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM25755.1 - 6.9e-09 35.4 0.2 8.2e-07 28.6 0.0 2.7 2 1 0 2 2 2 1 Kinase-like Pkinase_C PF00433.24 KFM25755.1 - 2.4e-05 24.9 0.1 5.9e-05 23.7 0.1 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Pkinase_fungal PF17667.1 KFM25755.1 - 3.7e-05 22.7 0.0 6.3e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KFM25755.1 - 0.00025 20.1 0.0 0.00045 19.3 0.0 1.3 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KFM25755.1 - 0.00064 19.7 0.0 0.0023 17.9 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KFM25755.1 - 0.0015 18.0 0.0 0.0024 17.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KFM25755.1 - 0.058 13.0 0.0 4.2 6.9 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KFM25755.1 - 0.13 11.8 0.2 0.4 10.3 0.0 1.7 2 0 0 2 2 2 0 RIO1 family Pox_ser-thr_kin PF05445.11 KFM25755.1 - 0.26 10.2 0.0 0.42 9.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PRP4 PF08799.11 KFM25756.1 - 3.9e-11 42.3 1.6 3.9e-11 42.3 1.6 3.1 4 0 0 4 4 4 1 pre-mRNA processing factor 4 (PRP4) like Prp18 PF02840.15 KFM25756.1 - 3.4e-08 33.7 0.0 7.5e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Prp18 domain Gag_p30 PF02093.16 KFM25756.1 - 0.049 13.1 0.0 0.33 10.5 0.0 2.0 2 0 0 2 2 2 0 Gag P30 core shell protein Tmemb_161AB PF10268.9 KFM25757.1 - 0.51 8.9 2.7 0.7 8.5 0.1 2.2 2 1 0 2 2 2 0 Predicted transmembrane protein 161AB Peptidase_S26 PF10502.9 KFM25758.1 - 3.2e-16 59.4 0.0 5.6e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 KFM25758.1 - 1e-11 44.6 0.0 2e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Acyl-CoA_dh_M PF02770.19 KFM25759.1 - 3e-19 69.0 0.2 7.2e-19 67.8 0.1 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain ACOX PF01756.19 KFM25759.1 - 3.8e-08 33.1 0.0 5.9e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_1 PF00441.24 KFM25759.1 - 0.0039 17.4 0.0 0.012 15.8 0.0 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DnaJ PF00226.31 KFM25760.1 - 4.5e-20 71.5 0.1 8e-20 70.7 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain RRM_1 PF00076.22 KFM25760.1 - 9.8e-05 22.1 0.0 0.00029 20.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) APG6_N PF17675.1 KFM25760.1 - 0.0016 19.0 5.4 0.0016 19.0 5.4 2.4 2 0 0 2 2 2 1 Apg6 coiled-coil region Z1 PF10593.9 KFM25760.1 - 0.012 15.1 0.1 0.02 14.4 0.1 1.4 1 0 0 1 1 1 0 Z1 domain PPDK_N PF01326.19 KFM25761.1 - 4.2e-18 65.7 0.0 8.4e-15 54.8 0.0 4.2 1 1 0 2 2 2 2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain CBM53 PF16760.5 KFM25761.1 - 0.042 14.4 0.0 0.18 12.4 0.0 2.1 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) Glyco_tran_28_C PF04101.16 KFM25762.1 - 2.5e-14 53.6 0.0 3.1e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glycos_transf_1 PF00534.20 KFM25762.1 - 1.2e-07 31.4 0.0 1.6e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KFM25762.1 - 5.1e-07 30.2 0.1 6.2e-07 29.9 0.1 1.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 MoCF_biosynth PF00994.24 KFM25762.1 - 0.13 11.9 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Probable molybdopterin binding domain MGDG_synth PF06925.11 KFM25763.1 - 2.1e-11 44.2 0.2 6.8e-10 39.3 0.1 2.0 1 1 1 2 2 2 2 Monogalactosyldiacylglycerol (MGDG) synthase Hexapep_loop PF18776.1 KFM25763.1 - 0.17 11.5 0.4 0.26 10.9 0.4 1.3 1 0 0 1 1 1 0 Hexapeptide repeat including loop Mut7-C PF01927.16 KFM25764.1 - 2.2e-21 76.5 0.0 2.5e-21 76.3 0.0 1.0 1 0 0 1 1 1 1 Mut7-C RNAse domain zinc_ribbon_5 PF13719.6 KFM25764.1 - 0.0098 15.6 1.8 1.2 8.9 0.3 2.5 2 0 0 2 2 2 2 zinc-ribbon domain zf-TFIIB PF13453.6 KFM25764.1 - 0.06 12.7 0.1 3 7.3 0.0 2.3 2 0 0 2 2 2 0 Transcription factor zinc-finger IF-2B PF01008.17 KFM25765.1 - 4.5e-58 196.7 0.0 6e-58 196.3 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Fe-S_biosyn PF01521.20 KFM25766.1 - 4.7e-18 65.4 0.0 5.7e-18 65.1 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis WD40 PF00400.32 KFM25767.1 - 1.1e-16 60.9 7.5 0.0059 17.4 0.2 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM25767.1 - 2.4e-08 34.2 0.4 0.73 10.2 0.1 5.1 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFM25767.1 - 0.00012 22.0 0.0 0.29 11.0 0.0 4.1 2 2 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A ELYS-bb PF16687.5 KFM25767.1 - 0.046 12.3 0.0 0.34 9.5 0.0 2.1 1 1 1 2 2 2 0 beta-propeller of ELYS nucleoporin Pyr_redox_2 PF07992.14 KFM25768.1 - 3.3e-69 233.4 8.1 4.4e-69 232.9 8.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KFM25768.1 - 8.1e-42 141.9 0.1 2.2e-41 140.5 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KFM25768.1 - 2.9e-22 79.0 9.7 1.4e-19 70.4 0.6 3.2 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KFM25768.1 - 5.1e-12 45.9 10.5 1.6e-10 40.9 2.2 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KFM25768.1 - 9.8e-11 41.5 4.0 2.2e-07 30.5 0.0 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFM25768.1 - 4.4e-08 32.7 1.7 0.0066 15.6 0.1 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 KFM25768.1 - 3.5e-07 29.6 16.3 1.2e-06 27.9 6.7 3.1 2 2 1 3 3 3 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KFM25768.1 - 3.6e-06 27.1 6.1 0.0004 20.5 1.1 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KFM25768.1 - 6.3e-06 25.5 3.6 6.3e-06 25.5 3.6 3.7 4 1 1 5 5 5 1 FAD binding domain AlaDh_PNT_C PF01262.21 KFM25768.1 - 1.1e-05 24.8 5.0 0.011 15.0 0.1 2.8 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KFM25768.1 - 1.7e-05 23.7 16.1 0.0012 17.6 1.8 4.0 3 1 1 4 4 4 2 HI0933-like protein FAD_binding_3 PF01494.19 KFM25768.1 - 6.9e-05 22.3 15.1 0.081 12.1 0.0 3.5 3 1 0 4 4 4 3 FAD binding domain Thi4 PF01946.17 KFM25768.1 - 0.0033 16.7 0.9 0.0033 16.7 0.9 2.8 2 1 1 3 3 3 1 Thi4 family 3HCDH_N PF02737.18 KFM25768.1 - 0.0095 15.8 0.1 0.0095 15.8 0.1 3.2 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KFM25768.1 - 0.033 14.6 4.5 1.1 9.7 0.5 3.2 3 1 0 3 3 3 0 Putative NAD(P)-binding TTRAP PF14203.6 KFM25768.1 - 0.048 13.6 0.0 3.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Putative tranposon-transfer assisting protein Lycopene_cycl PF05834.12 KFM25768.1 - 0.048 12.7 4.6 0.14 11.1 0.1 2.7 3 0 0 3 3 3 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.14 KFM25768.1 - 0.096 12.3 0.1 0.096 12.3 0.1 3.0 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.24 KFM25768.1 - 2.5 7.6 21.0 5.2 6.6 2.2 3.8 3 1 0 4 4 4 0 FAD dependent oxidoreductase Helicase_C PF00271.31 KFM25769.1 - 4.5e-10 39.9 0.0 1e-09 38.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KFM25769.1 - 2.6e-08 33.0 0.0 3.8e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Phage_holin_8 PF16931.5 KFM25769.1 - 0.031 14.2 1.2 0.059 13.3 1.2 1.4 1 0 0 1 1 1 0 Putative phage holin IFP_35_N PF07334.13 KFM25770.1 - 0.078 13.1 0.2 2.3 8.3 0.1 2.9 3 0 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus MHC_I PF00129.18 KFM25770.1 - 9.8 5.7 7.8 0.23 11.0 1.2 1.6 2 0 0 2 2 2 0 Class I Histocompatibility antigen, domains alpha 1 and 2 WD40 PF00400.32 KFM25771.1 - 5.3e-21 74.5 1.9 1.5e-05 25.6 0.0 5.8 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM25771.1 - 6.7e-15 55.2 0.0 0.0096 16.2 0.0 5.1 3 2 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 KFM25771.1 - 0.00044 18.7 0.0 0.14 10.5 0.0 2.6 3 0 0 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz Nup160 PF11715.8 KFM25771.1 - 0.058 12.0 0.0 0.74 8.4 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 DUF866 PF05907.13 KFM25772.1 - 2.2e-36 125.1 0.0 2.4e-36 125.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Cullin PF00888.22 KFM25773.1 - 4e-173 577.4 0.0 4.9e-173 577.1 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KFM25773.1 - 2e-21 75.8 2.3 4.1e-21 74.8 2.3 1.6 1 0 0 1 1 1 1 Cullin protein neddylation domain HSP70 PF00012.20 KFM25774.1 - 1.4e-181 604.8 1.9 1.1e-144 482.9 1.3 2.1 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 KFM25774.1 - 2.2e-12 46.5 0.0 3.5e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein Exo_endo_phos PF03372.23 KFM25774.1 - 5.2e-09 36.0 0.0 1.4e-08 34.6 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF756 PF05506.12 KFM25774.1 - 0.036 15.0 0.0 0.1 13.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF756) DUF1464 PF07318.12 KFM25774.1 - 0.045 12.9 0.0 0.084 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1464) Metallophos PF00149.28 KFM25775.1 - 1e-35 124.1 0.1 1.3e-35 123.7 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KFM25775.1 - 0.012 16.0 0.0 0.026 15.0 0.0 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain DUF2321 PF10083.9 KFM25775.1 - 0.063 12.9 0.8 4 7.0 0.2 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Metallophos_2 PF12850.7 KFM25775.1 - 0.081 13.1 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Mg_trans_NIPA PF05653.14 KFM25777.1 - 0.082 12.0 1.9 0.11 11.5 1.9 1.2 1 0 0 1 1 1 0 Magnesium transporter NIPA CBFD_NFYB_HMF PF00808.23 KFM25778.1 - 6.3e-09 36.0 0.0 9.4e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFM25778.1 - 0.00021 21.7 0.0 0.0003 21.1 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 GPI2 PF06432.11 KFM25779.1 - 2.8e-24 86.0 10.8 1.6e-14 54.0 4.6 2.2 1 1 2 3 3 3 2 Phosphatidylinositol N-acetylglucosaminyltransferase TFIIB PF00382.19 KFM25779.1 - 0.34 11.0 0.3 0.34 11.0 0.3 1.6 2 0 0 2 2 2 0 Transcription factor TFIIB repeat CreD PF06123.12 KFM25779.1 - 0.66 8.7 2.5 0.85 8.3 2.5 1.1 1 0 0 1 1 1 0 Inner membrane protein CreD DoxX_2 PF13564.6 KFM25779.1 - 7.9 6.7 12.7 26 5.0 3.1 2.1 1 1 1 2 2 2 0 DoxX-like family Borealin PF10512.9 KFM25780.1 - 2 8.4 4.2 2.3 8.2 4.2 1.1 1 0 0 1 1 1 0 Cell division cycle-associated protein 8 MutS_V PF00488.21 KFM25781.1 - 7.8e-76 254.3 0.1 1.4e-75 253.5 0.1 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KFM25781.1 - 2.1e-30 106.4 5.0 5e-30 105.1 5.0 1.7 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 KFM25781.1 - 8.1e-10 38.9 1.0 1.8e-09 37.8 1.0 1.6 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 KFM25781.1 - 0.00026 21.3 0.1 0.001 19.4 0.0 2.0 2 0 0 2 2 2 1 MutS domain II Atg14 PF10186.9 KFM25781.1 - 0.066 12.3 0.8 0.11 11.6 0.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Pkinase_Tyr PF07714.17 KFM25782.1 - 2.1e-41 141.9 0.0 2.9e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM25782.1 - 1.5e-34 119.6 0.0 2.3e-34 119.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KFM25782.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFM25782.1 - 0.017 13.9 0.0 0.024 13.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KFM25782.1 - 0.021 14.8 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1679 PF07914.11 KFM25782.1 - 0.043 12.7 0.0 0.064 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Kinase-like PF14531.6 KFM25782.1 - 0.1 11.9 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like MutS_V PF00488.21 KFM25783.1 - 2.7e-40 138.4 0.0 4.6e-40 137.7 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.20 KFM25783.1 - 6.5e-13 48.9 0.0 1.2e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 MutS domain I GIY-YIG PF01541.24 KFM25783.1 - 4.2e-05 23.7 0.0 8.3e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain AAA_29 PF13555.6 KFM25783.1 - 0.22 11.3 0.2 0.64 9.8 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain 3HCDH_N PF02737.18 KFM25784.1 - 3e-56 190.1 0.0 4.6e-56 189.6 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 KFM25784.1 - 1.3e-42 145.9 0.0 2.3e-42 145.1 0.0 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 KFM25784.1 - 1.1e-31 109.2 0.2 1.2e-23 83.6 0.0 2.6 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 KFM25784.1 - 2.8e-26 92.8 0.0 5.3e-26 91.9 0.0 1.5 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Pyr_redox_2 PF07992.14 KFM25784.1 - 0.047 12.9 0.2 0.1 11.8 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase LpxC PF03331.13 KFM25785.1 - 3.4e-50 171.0 0.0 1.7e-40 139.2 0.0 2.1 2 0 0 2 2 2 2 UDP-3-O-acyl N-acetylglycosamine deacetylase Ank_4 PF13637.6 KFM25786.1 - 1.7e-10 41.2 0.4 7.2e-05 23.3 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM25786.1 - 3.6e-08 33.9 0.0 5e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KFM25786.1 - 1.4e-06 28.5 0.0 0.00044 20.6 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 KFM25786.1 - 4.3e-05 23.6 0.1 0.012 16.1 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 KFM25786.1 - 0.0017 18.6 0.1 0.003 17.9 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Metallophos PF00149.28 KFM25788.1 - 4.6e-33 115.5 0.0 5.4e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KFM25788.1 - 1.7e-09 38.0 7.9 2e-09 37.8 1.0 2.5 1 1 1 2 2 2 2 Serine-threonine protein phosphatase N-terminal domain TAF PF02969.17 KFM25789.1 - 1.2e-18 67.0 0.0 2.2e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) TAF6_C PF07571.13 KFM25789.1 - 7.9e-17 61.4 0.0 1.5e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain Histone PF00125.24 KFM25789.1 - 0.011 16.1 0.2 0.019 15.3 0.2 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 HEAT PF02985.22 KFM25789.1 - 0.011 15.9 0.5 1.7 9.1 0.1 3.1 2 0 0 2 2 2 0 HEAT repeat CENP-S PF15630.6 KFM25789.1 - 0.054 13.9 0.1 0.11 12.9 0.1 1.4 1 0 0 1 1 1 0 CENP-S protein TFIID-31kDa PF02291.15 KFM25789.1 - 0.077 13.1 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit SLATT_3 PF18184.1 KFM25789.1 - 0.1 12.7 0.2 0.1 12.7 0.2 1.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 3 HEAT_2 PF13646.6 KFM25789.1 - 0.58 10.6 11.5 0.25 11.7 6.9 3.0 2 1 0 2 2 2 0 HEAT repeats 4HBT PF03061.22 KFM25790.1 - 1.1e-07 32.1 0.0 1.9e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Abhydrolase_1 PF00561.20 KFM25791.1 - 1.8e-25 90.1 0.2 1e-24 87.6 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFM25791.1 - 7.8e-18 65.9 0.3 9e-18 65.7 0.3 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFM25791.1 - 3.1e-11 43.0 0.0 2.6e-10 40.0 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 KFM25791.1 - 0.0014 18.2 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KFM25791.1 - 0.021 14.6 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein VHS PF00790.19 KFM25792.1 - 1.9e-22 79.7 0.0 2.7e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 VHS domain Spc7 PF08317.11 KFM25793.1 - 0.0013 17.7 4.1 0.0016 17.4 4.1 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein CCDC144C PF14915.6 KFM25793.1 - 0.0042 16.3 4.9 0.0052 15.9 4.9 1.1 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region CENP-H PF05837.12 KFM25793.1 - 0.0058 17.0 5.7 0.0068 16.8 4.7 1.6 1 1 0 1 1 1 1 Centromere protein H (CENP-H) Flagellin_C PF00700.21 KFM25793.1 - 0.006 16.9 1.6 1.4 9.4 0.0 3.1 2 1 1 3 3 3 1 Bacterial flagellin C-terminal helical region Tropomyosin PF00261.20 KFM25793.1 - 0.0073 15.7 8.1 0.048 13.0 6.7 1.9 1 1 0 1 1 1 1 Tropomyosin UPF0242 PF06785.11 KFM25793.1 - 0.011 15.8 1.4 0.013 15.6 1.4 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF3618 PF12277.8 KFM25793.1 - 0.02 15.1 10.3 0.98 9.7 0.1 4.3 4 1 0 4 4 3 0 Protein of unknown function (DUF3618) DUF4349 PF14257.6 KFM25793.1 - 0.021 14.3 10.1 0.023 14.1 7.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) V-SNARE_C PF12352.8 KFM25793.1 - 0.031 14.6 3.0 1 9.7 0.1 2.9 2 1 1 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus MscS_porin PF12795.7 KFM25793.1 - 0.039 13.5 7.4 0.097 12.2 2.0 2.1 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain MPS2 PF17060.5 KFM25793.1 - 0.047 13.0 1.8 0.061 12.6 1.8 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 DUF745 PF05335.13 KFM25793.1 - 0.048 13.4 2.2 0.063 13.0 1.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF745) JIP_LZII PF16471.5 KFM25793.1 - 0.057 13.6 5.2 0.17 12.1 3.1 2.2 1 1 2 3 3 3 0 JNK-interacting protein leucine zipper II VGPC1_C PF16799.5 KFM25793.1 - 0.061 13.3 1.0 0.22 11.5 0.2 2.0 2 0 0 2 2 2 0 C-terminal membrane-localisation domain of ion-channel, VCN1 Golgin_A5 PF09787.9 KFM25793.1 - 0.069 12.6 4.8 0.12 11.8 4.8 1.3 1 1 0 1 1 1 0 Golgin subfamily A member 5 Atg14 PF10186.9 KFM25793.1 - 0.07 12.2 6.6 0.084 11.9 6.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Bcr-Abl_Oligo PF09036.10 KFM25793.1 - 0.076 13.0 3.9 0.6 10.2 0.0 3.0 1 1 3 4 4 4 0 Bcr-Abl oncoprotein oligomerisation domain Fez1 PF06818.15 KFM25793.1 - 0.11 13.0 5.5 0.19 12.2 5.5 1.5 1 1 0 1 1 1 0 Fez1 TMF_TATA_bd PF12325.8 KFM25793.1 - 0.11 12.7 7.7 4 7.7 3.4 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding COG2 PF06148.11 KFM25793.1 - 0.12 12.4 2.4 1.3 9.1 0.7 2.1 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 OEP PF02321.18 KFM25793.1 - 0.23 11.3 3.8 0.23 11.2 2.3 1.7 2 0 0 2 2 2 0 Outer membrane efflux protein TPR_MLP1_2 PF07926.12 KFM25793.1 - 0.33 11.0 7.6 3.7 7.6 7.2 2.1 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein CALCOCO1 PF07888.11 KFM25793.1 - 0.36 9.7 12.0 0.43 9.4 12.0 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Exonuc_VII_L PF02601.15 KFM25793.1 - 0.37 10.3 4.1 0.47 10.0 4.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Syntaxin-6_N PF09177.11 KFM25793.1 - 0.41 11.2 4.9 1.8 9.1 4.8 1.9 1 1 1 2 2 2 0 Syntaxin 6, N-terminal FUSC PF04632.12 KFM25793.1 - 4.2 5.8 7.3 5.1 5.5 7.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family MerR-DNA-bind PF09278.11 KFM25793.1 - 6.6 7.4 9.8 6.2 7.4 3.1 2.9 3 1 0 3 3 3 0 MerR, DNA binding Malic_M PF03949.15 KFM25795.1 - 1.2e-87 293.4 0.0 1.7e-87 292.9 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KFM25795.1 - 1.6e-65 220.4 0.0 7.9e-65 218.1 0.0 1.9 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain Dcc1 PF09724.9 KFM25796.1 - 7.8e-60 202.9 0.0 8.6e-60 202.8 0.0 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 HTH_53 PF18606.1 KFM25796.1 - 0.028 14.1 2.0 0.1 12.2 0.6 2.5 3 0 0 3 3 3 0 Zap helix turn helix N-terminal domain PS-DH PF14765.6 KFM25796.1 - 0.029 13.6 0.2 0.044 13.0 0.2 1.2 1 0 0 1 1 1 0 Polyketide synthase dehydratase Glyco_transf_92 PF01697.27 KFM25797.1 - 1.9e-10 40.9 0.0 3.7e-10 39.9 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 KFM25797.1 - 1.3e-09 38.4 0.0 3.2e-09 37.2 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 PSP PF04046.16 KFM25798.1 - 3.2e-13 49.3 1.6 1e-12 47.7 1.6 1.9 1 0 0 1 1 1 1 PSP ICMT PF04140.14 KFM25799.1 - 1.8e-24 86.0 0.4 3.2e-24 85.2 0.4 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KFM25799.1 - 3.1e-08 34.0 0.8 3.1e-08 34.0 0.8 1.5 2 0 0 2 2 2 1 Phospholipid methyltransferase NnrU PF07298.11 KFM25799.1 - 0.011 15.3 1.6 0.031 13.8 1.7 1.8 1 1 0 1 1 1 0 NnrU protein DUF1295 PF06966.12 KFM25799.1 - 0.013 15.1 0.3 0.014 15.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) Jas PF16135.5 KFM25801.1 - 9.7e-22 76.9 0.8 6.1e-13 48.8 0.0 2.7 2 0 0 2 2 2 2 TPL-binding domain in jasmonate signalling PHD PF00628.29 KFM25801.1 - 7.2e-07 29.0 18.6 0.00011 22.0 8.3 3.3 4 0 0 4 4 4 2 PHD-finger BON PF04972.17 KFM25801.1 - 0.002 18.4 1.5 0.41 11.0 0.0 4.0 3 0 0 3 3 3 1 BON domain zf-HC5HC2H_2 PF13832.6 KFM25801.1 - 0.0052 16.9 6.2 0.22 11.7 0.2 2.7 2 0 0 2 2 2 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KFM25801.1 - 0.12 12.6 13.8 0.19 12.0 0.1 2.8 3 0 0 3 3 3 0 PHD-like zinc-binding domain PHD_2 PF13831.6 KFM25801.1 - 2.9 7.5 18.5 0.017 14.7 3.6 3.1 3 0 0 3 3 3 0 PHD-finger Alfin PF12165.8 KFM25802.1 - 3.3e-58 194.9 0.0 4.4e-58 194.5 0.0 1.2 1 0 0 1 1 1 1 Alfin PHD PF00628.29 KFM25802.1 - 1.7e-08 34.2 6.2 2.9e-08 33.5 6.2 1.4 1 0 0 1 1 1 1 PHD-finger zf-C2HC_2 PF13913.6 KFM25802.1 - 0.018 14.9 1.0 0.018 14.9 1.0 3.0 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-RING_2 PF13639.6 KFM25802.1 - 0.033 14.5 4.8 0.066 13.6 4.8 1.5 1 0 0 1 1 1 0 Ring finger domain Prok-RING_1 PF14446.6 KFM25802.1 - 0.054 13.4 1.0 0.054 13.4 1.0 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DZR PF12773.7 KFM25802.1 - 0.083 12.9 4.2 0.25 11.4 4.3 1.8 1 1 0 1 1 1 0 Double zinc ribbon Rad50_zn_hook PF04423.14 KFM25802.1 - 0.33 10.8 2.3 2.5 8.0 0.5 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif Prok-RING_4 PF14447.6 KFM25802.1 - 1 9.3 4.0 36 4.3 1.9 2.7 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C2H2_4 PF13894.6 KFM25802.1 - 2.3 9.3 11.0 33 5.7 0.2 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-RING_7 PF02591.15 KFM25802.1 - 3 8.1 8.0 6.3 7.1 0.2 3.0 3 0 0 3 3 2 0 C4-type zinc ribbon domain zf-H2C2_2 PF13465.6 KFM25802.1 - 4.1 8.0 10.2 15 6.2 0.5 3.3 3 0 0 3 3 3 0 Zinc-finger double domain zf-ribbon_3 PF13248.6 KFM25802.1 - 4.3 6.9 10.4 0.59 9.6 3.7 2.6 2 1 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 KFM25802.1 - 7.4 6.8 8.0 7.3e+02 0.4 8.0 2.4 1 1 0 1 1 1 0 Zinc ribbon domain SMC_N PF02463.19 KFM25803.1 - 3.6e-20 72.4 0.0 5.2e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KFM25803.1 - 2e-15 57.9 2.6 3e-14 54.0 0.0 3.4 2 2 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KFM25803.1 - 0.0021 17.9 1.4 0.45 10.3 0.4 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFM25803.1 - 0.01 15.6 0.0 0.026 14.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_13 PF13166.6 KFM25803.1 - 0.062 12.0 15.9 2.7 6.5 4.7 3.9 3 1 1 4 4 4 0 AAA domain ABC_tran PF00005.27 KFM25803.1 - 0.25 11.9 3.0 0.51 10.8 0.0 3.0 3 0 0 3 3 3 0 ABC transporter DUF1178 PF06676.11 KFM25803.1 - 0.67 10.3 3.3 0.42 11.0 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) IFT57 PF10498.9 KFM25803.1 - 2.8 6.8 7.3 3 6.7 0.3 2.7 2 1 0 2 2 2 0 Intra-flagellar transport protein 57 DUF1664 PF07889.12 KFM25803.1 - 2.8 8.0 5.8 9.3 6.3 0.1 4.0 5 0 0 5 5 5 0 Protein of unknown function (DUF1664) TIC20 PF16166.5 KFM25804.1 - 2.1e-30 105.9 3.0 2.5e-30 105.6 3.0 1.0 1 0 0 1 1 1 1 Chloroplast import apparatus Tic20-like Pro_isomerase PF00160.21 KFM25806.1 - 4.2e-41 140.9 0.1 1.5e-40 139.0 0.1 1.7 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3730 PF12530.8 KFM25810.1 - 1.3e-18 67.4 0.3 3.2e-18 66.2 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3730) Arm PF00514.23 KFM25810.1 - 0.085 12.9 0.3 0.085 12.9 0.3 4.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Nrap_D5 PF17406.2 KFM25811.1 - 0.039 13.7 0.1 0.067 12.9 0.1 1.4 1 0 0 1 1 1 0 Nrap protein PAP/OAS1-like domain 5 YchF-GTPase_C PF06071.13 KFM25812.1 - 4.9e-40 135.6 0.2 1.9e-39 133.7 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KFM25812.1 - 4.2e-23 81.6 0.0 8.7e-23 80.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFM25812.1 - 1.2e-07 31.4 0.0 3.1e-07 30.1 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KFM25812.1 - 0.0066 16.4 0.2 1 9.2 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1_C PF08438.10 KFM25812.1 - 0.053 14.1 0.1 0.94 10.1 0.0 2.3 2 0 0 2 2 2 0 GTPase of unknown function C-terminal ABC_tran PF00005.27 KFM25812.1 - 0.062 13.8 0.0 0.15 12.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter APG6_N PF17675.1 KFM25812.1 - 0.1 13.1 0.1 0.3 11.6 0.0 1.7 2 0 0 2 2 2 0 Apg6 coiled-coil region Na_Ca_ex PF01699.24 KFM25814.1 - 3.1e-37 127.9 43.1 9.1e-20 71.1 20.9 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein COPIIcoated_ERV PF07970.12 KFM25815.1 - 1.6e-75 253.8 0.0 2.2e-75 253.3 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KFM25815.1 - 1e-27 96.3 0.0 2.1e-27 95.3 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) UQ_con PF00179.26 KFM25817.1 - 3.6e-54 182.2 0.0 4.1e-54 182.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFM25817.1 - 0.00041 20.6 0.0 0.00057 20.2 0.0 1.4 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 KFM25817.1 - 0.0013 18.4 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KFM25817.1 - 0.02 14.7 0.1 0.032 14.1 0.1 1.3 1 0 0 1 1 1 0 UEV domain Cas9-BH PF16593.5 KFM25818.1 - 0.073 12.8 0.0 0.073 12.8 0.0 1.9 2 0 0 2 2 2 0 Bridge helix of CRISPR-associated endonuclease Cas9 Hist_deacetyl PF00850.19 KFM25821.1 - 1.2e-25 90.6 0.0 1.5e-24 87.1 0.0 2.2 1 1 1 2 2 2 1 Histone deacetylase domain Ank PF00023.30 KFM25821.1 - 3.3e-10 39.9 0.1 0.0017 18.7 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KFM25821.1 - 7.2e-10 39.3 0.1 0.0012 19.3 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFM25821.1 - 2.4e-07 30.9 3.3 0.027 14.8 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFM25821.1 - 3.5e-07 30.7 2.5 0.021 15.4 0.8 3.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM25821.1 - 4.8e-07 29.6 0.2 0.081 13.5 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ribosomal_S30AE PF02482.19 KFM25822.1 - 3.3e-21 75.9 2.8 6.7e-21 74.9 2.8 1.5 1 0 0 1 1 1 1 Sigma 54 modulation protein / S30EA ribosomal protein Ribosom_S30AE_C PF16321.5 KFM25822.1 - 3.4e-13 49.1 4.5 1.1e-07 31.4 0.3 2.6 3 0 0 3 3 3 2 Sigma 54 modulation/S30EA ribosomal protein C terminus Yip1 PF04893.17 KFM25822.1 - 7.2e-11 42.1 18.9 1.1e-10 41.5 18.9 1.2 1 0 0 1 1 1 1 Yip1 domain FAM92 PF06730.11 KFM25822.1 - 0.4 10.1 1.3 0.62 9.4 0.5 1.7 2 0 0 2 2 2 0 FAM92 protein Autophagy_act_C PF03987.15 KFM25823.1 - 7.9e-15 55.2 0.2 1.4e-14 54.4 0.2 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain DUF3119 PF11317.8 KFM25824.1 - 1.1e-39 135.6 0.1 1.5e-39 135.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3119) DUF2298 PF10060.9 KFM25824.1 - 0.062 12.0 0.0 0.07 11.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized membrane protein (DUF2298) PFU PF09070.11 KFM25825.1 - 0.1 12.8 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 PFU (PLAA family ubiquitin binding) DUF218 PF02698.17 KFM25827.1 - 1e-09 38.5 0.0 1.2e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 DUF218 domain DUF659 PF04937.15 KFM25829.1 - 1e-16 61.1 0.7 1.4e-15 57.4 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF 659) Big_9 PF17963.1 KFM25830.1 - 0.18 12.5 4.4 0.49 11.2 4.4 1.8 1 1 0 1 1 1 0 Bacterial Ig domain Period_C PF12114.8 KFM25830.1 - 5 6.7 10.2 6.5 6.3 10.2 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region DUF1802 PF08819.11 KFM25831.1 - 2.9e-25 89.1 0.0 3.5e-25 88.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1802) TIP49 PF06068.13 KFM25832.1 - 3.6e-156 519.8 0.7 4.8e-156 519.4 0.7 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KFM25832.1 - 1.5e-21 76.3 0.4 4.1e-21 74.9 0.4 1.8 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 KFM25832.1 - 1.8e-09 38.1 2.5 6e-07 29.9 0.2 3.1 2 1 1 3 3 3 1 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.15 KFM25832.1 - 2.6e-06 26.9 1.1 4.5e-06 26.2 1.1 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain RuvB_N PF05496.12 KFM25832.1 - 3.4e-06 26.9 0.7 0.0043 16.8 0.1 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KFM25832.1 - 6.4e-06 26.2 0.1 0.0024 17.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFM25832.1 - 2.4e-05 24.8 0.2 0.00019 21.8 0.2 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 KFM25832.1 - 6.2e-05 23.4 1.9 0.00068 20.0 1.9 2.3 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KFM25832.1 - 6.8e-05 22.4 1.1 0.0022 17.4 0.4 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KFM25832.1 - 7.1e-05 23.1 0.2 0.3 11.4 0.0 2.6 2 1 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 KFM25832.1 - 0.00024 20.9 0.1 0.24 11.1 0.1 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain ATPase PF06745.13 KFM25832.1 - 0.00032 20.1 1.6 0.00058 19.3 1.6 1.3 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.6 KFM25832.1 - 0.0004 20.0 0.1 0.0011 18.6 0.1 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KFM25832.1 - 0.0018 17.6 0.2 0.0041 16.4 0.2 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_7 PF12775.7 KFM25832.1 - 0.0029 17.1 0.1 0.013 15.0 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_17 PF13207.6 KFM25832.1 - 0.02 15.3 1.0 0.058 13.8 1.0 1.9 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KFM25832.1 - 0.037 13.9 0.0 0.071 13.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain TsaE PF02367.17 KFM25832.1 - 0.038 14.0 0.1 0.096 12.7 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2075 PF09848.9 KFM25832.1 - 0.039 13.2 0.0 0.061 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.14 KFM25832.1 - 0.042 13.0 0.7 1.5 8.0 0.1 2.1 2 0 0 2 2 2 0 PIF1-like helicase ResIII PF04851.15 KFM25832.1 - 0.044 13.8 0.3 1.1 9.2 0.2 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_33 PF13671.6 KFM25832.1 - 0.1 12.7 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 KFM25832.1 - 0.11 12.6 2.9 0.28 11.3 0.6 2.5 1 1 2 3 3 3 0 AAA domain (Cdc48 subfamily) YtkA PF13115.6 KFM25832.1 - 0.13 12.9 0.1 0.27 11.9 0.1 1.5 1 0 0 1 1 1 0 YtkA-like HMG_box PF00505.19 KFM25834.1 - 3.5e-17 62.6 5.0 1.8e-16 60.3 5.0 2.1 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFM25834.1 - 3.9e-09 37.0 2.3 1.4e-08 35.2 2.3 1.9 1 1 0 1 1 1 1 HMG-box domain DUF2582 PF10771.9 KFM25834.1 - 0.0047 17.0 0.1 0.0069 16.5 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix domain (DUF2582) COPIIcoated_ERV PF07970.12 KFM25835.1 - 1.9e-37 129.3 0.0 3e-37 128.6 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KFM25835.1 - 2.1e-21 76.0 0.0 3.4e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DapB_C PF05173.14 KFM25836.1 - 1.6e-18 66.9 0.2 3.1e-18 66.0 0.1 1.5 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, C-terminus DapB_N PF01113.20 KFM25836.1 - 3.5e-10 40.1 0.0 6.5e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Nitro_FeMo-Co PF02579.17 KFM25836.1 - 0.05 13.9 0.1 3.3 8.1 0.0 2.7 3 0 0 3 3 3 0 Dinitrogenase iron-molybdenum cofactor Skp1 PF01466.19 KFM25837.1 - 1.8e-28 98.4 0.2 4.2e-28 97.2 0.2 1.7 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KFM25837.1 - 2.7e-23 81.9 0.1 2.4e-22 78.9 0.0 2.3 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Gar1 PF04410.14 KFM25837.1 - 3.3e-18 65.9 0.0 9.3e-18 64.5 0.0 1.6 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region DNA_gyraseB PF00204.25 KFM25838.1 - 1.5e-52 177.6 0.0 2.1e-52 177.1 0.0 1.2 1 0 0 1 1 1 1 DNA gyrase B DNA_gyraseB_C PF00986.21 KFM25838.1 - 5.3e-25 87.4 0.2 1.1e-24 86.3 0.0 1.7 2 0 0 2 2 2 1 DNA gyrase B subunit, carboxyl terminus HATPase_c PF02518.26 KFM25838.1 - 4.6e-18 65.8 0.0 9.7e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KFM25838.1 - 2.9e-15 56.4 0.0 6.9e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 Toprim domain IPP-2 PF04979.14 KFM25839.1 - 5.6e-16 59.5 0.3 1e-15 58.6 0.3 1.4 1 1 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) Arm PF00514.23 KFM25840.1 - 1.1e-08 34.9 26.1 0.00065 19.6 0.1 6.4 7 0 0 7 7 7 3 Armadillo/beta-catenin-like repeat DUF2267 PF10025.9 KFM25840.1 - 3.7 7.9 5.6 4.7 7.5 2.1 2.8 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2267) ABC_membrane_2 PF06472.15 KFM25841.1 - 5.5e-56 189.9 0.6 7.6e-56 189.5 0.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 SbmA_BacA PF05992.12 KFM25841.1 - 1.6e-17 64.0 0.6 1.1e-16 61.2 0.6 2.1 1 1 0 1 1 1 1 SbmA/BacA-like family ABC_tran PF00005.27 KFM25841.1 - 9.5e-16 58.6 0.0 2e-15 57.5 0.0 1.5 1 1 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KFM25841.1 - 5.3e-11 42.7 1.8 7.2e-11 42.2 1.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_30 PF13604.6 KFM25841.1 - 4.5e-06 26.5 0.5 0.0048 16.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KFM25841.1 - 0.00013 22.4 2.9 0.00078 19.9 1.4 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KFM25841.1 - 0.00085 19.2 0.1 0.037 13.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFM25841.1 - 0.00092 18.7 0.0 0.36 10.2 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KFM25841.1 - 0.0035 17.1 0.1 0.0096 15.6 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.12 KFM25841.1 - 0.0052 16.7 0.0 0.0093 15.9 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KFM25841.1 - 0.012 15.9 0.8 0.036 14.4 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KFM25841.1 - 0.016 15.7 0.0 0.058 13.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KFM25841.1 - 0.017 14.9 0.2 0.47 10.2 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA PF00004.29 KFM25841.1 - 0.028 14.9 0.2 0.085 13.3 0.1 1.9 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KFM25841.1 - 0.029 13.5 0.2 0.057 12.5 0.2 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein RsgA_GTPase PF03193.16 KFM25841.1 - 0.03 14.2 0.1 0.056 13.3 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_7 PF12775.7 KFM25841.1 - 0.076 12.5 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 KFM25841.1 - 0.17 11.9 0.0 2.2 8.3 0.0 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Metallophos PF00149.28 KFM25842.1 - 9.5e-14 52.4 0.2 1.3e-13 52.0 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFM25842.1 - 4.3e-06 27.0 0.2 8.5e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain TPR_16 PF13432.6 KFM25842.1 - 0.043 14.5 1.0 0.3 11.8 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat NUDIX_4 PF14815.6 KFM25844.1 - 0.013 15.5 0.1 0.036 14.1 0.0 1.8 2 1 0 2 2 2 0 NUDIX domain NUDIX PF00293.28 KFM25844.1 - 0.56 10.3 5.7 0.9 9.6 0.3 2.7 3 1 1 4 4 4 0 NUDIX domain WD40 PF00400.32 KFM25845.1 - 5.6e-16 58.6 16.0 0.0049 17.7 0.1 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM25845.1 - 1.8e-10 40.9 0.8 0.056 13.8 0.0 4.5 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain PPDFL PF15060.6 KFM25845.1 - 0.03 14.8 0.0 0.066 13.7 0.0 1.5 1 0 0 1 1 1 0 Differentiation and proliferation regulator Ge1_WD40 PF16529.5 KFM25845.1 - 0.14 11.1 1.3 7.2 5.5 0.1 3.3 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF2807 PF10988.8 KFM25846.1 - 2.6e-13 50.1 0.4 2.6e-13 50.1 0.4 2.0 2 0 0 2 2 2 1 Putative auto-transporter adhesin, head GIN domain p25-alpha PF05517.12 KFM25846.1 - 1.2e-12 48.2 0.0 1.9e-11 44.4 0.0 2.4 2 1 0 2 2 2 1 p25-alpha EF-hand_7 PF13499.6 KFM25846.1 - 3.6e-08 33.7 1.0 4.2e-07 30.3 2.6 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KFM25846.1 - 0.00044 19.6 0.6 0.18 11.4 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KFM25846.1 - 0.0028 17.4 1.8 1.9 8.7 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain LGFP PF08310.11 KFM25846.1 - 0.042 14.4 0.7 0.15 12.6 0.7 2.0 1 0 0 1 1 1 0 LGFP repeat DAO PF01266.24 KFM25847.1 - 6.1e-52 177.3 3.0 8.9e-52 176.8 3.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 KFM25847.1 - 7.1e-37 126.1 0.0 1.2e-36 125.3 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 KFM25847.1 - 1.4e-11 44.1 3.3 1.4e-11 44.1 3.3 2.1 2 1 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 KFM25847.1 - 8.4e-09 35.3 0.3 6.7e-06 25.7 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KFM25847.1 - 1.5e-05 24.4 0.0 0.15 11.3 0.0 2.6 3 0 0 3 3 3 2 FAD binding domain GIDA PF01134.22 KFM25847.1 - 0.0006 19.0 0.6 0.04 13.0 0.2 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KFM25847.1 - 0.00067 19.0 0.0 0.0014 17.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFM25847.1 - 0.014 14.1 0.3 0.024 13.3 0.3 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 KFM25847.1 - 0.038 13.2 0.1 0.16 11.2 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFM25847.1 - 0.1 13.2 0.2 2.6 8.7 0.1 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFM25847.1 - 6.1 7.2 7.8 0.15 12.3 0.4 2.3 3 0 0 3 3 2 0 NAD(P)-binding Rossmann-like domain Cytochrom_C1 PF02167.15 KFM25848.1 - 2.2e-98 328.3 0.0 2.6e-98 328.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 KFM25848.1 - 0.00023 21.4 0.0 0.00062 20.0 0.0 1.8 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 KFM25848.1 - 0.00043 21.4 1.0 0.0077 17.3 0.1 2.8 3 1 0 3 3 3 1 Cytochrome c CytB6-F_Fe-S PF08802.10 KFM25848.1 - 0.08 13.0 2.6 0.67 10.0 0.0 2.6 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit Complex1_51K PF01512.17 KFM25849.1 - 5.5e-44 149.7 0.0 1.3e-43 148.5 0.0 1.6 2 0 0 2 2 2 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 KFM25849.1 - 4.1e-29 100.5 0.0 8.4e-29 99.5 0.0 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 KFM25849.1 - 2.7e-07 30.3 0.0 7.2e-07 29.0 0.0 1.8 1 0 0 1 1 1 1 SLBB domain PP2C PF00481.21 KFM25850.1 - 7.7e-43 147.0 0.0 1.2e-42 146.3 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 KFM25850.1 - 1.5e-11 43.8 10.2 4.9e-08 32.6 3.4 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRRNT_2 PF08263.12 KFM25850.1 - 9.9e-08 32.2 1.6 2.4e-07 30.9 1.6 1.7 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_4 PF12799.7 KFM25850.1 - 2.6e-07 30.9 13.8 0.00038 20.8 0.3 2.9 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM25850.1 - 0.00096 19.4 5.3 4.7 8.1 0.0 4.9 5 0 0 5 5 5 1 Leucine Rich Repeat PP2C_2 PF13672.6 KFM25850.1 - 0.048 13.3 3.8 0.097 12.3 3.8 1.4 1 0 0 1 1 1 0 Protein phosphatase 2C CD34_antigen PF06365.12 KFM25850.1 - 0.06 12.9 0.0 0.099 12.2 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family Amnionless PF14828.6 KFM25850.1 - 0.088 11.6 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 Amnionless Beta-APP PF03494.13 KFM25850.1 - 0.28 11.1 1.7 0.66 9.9 1.7 1.6 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) LRR_6 PF13516.6 KFM25850.1 - 0.34 11.1 14.9 29 5.0 0.1 5.8 5 0 0 5 5 5 0 Leucine Rich repeat His_Phos_1 PF00300.22 KFM25852.1 - 6.2e-35 120.6 0.9 8.6e-35 120.2 0.9 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PTR2 PF00854.21 KFM25853.1 - 8.8e-107 357.3 5.1 8.8e-107 357.3 5.1 1.8 2 0 0 2 2 2 1 POT family MFS_1 PF07690.16 KFM25853.1 - 2e-05 23.7 30.9 2e-05 23.7 30.9 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily C2 PF00168.30 KFM25855.1 - 1.1e-13 51.3 0.0 1.7e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 C2 domain MMM1 PF10296.9 KFM25855.1 - 0.0029 16.7 0.0 0.0046 16.0 0.0 1.2 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 BRI3BP PF14965.6 KFM25855.1 - 0.25 10.8 2.5 0.64 9.5 2.5 1.6 1 0 0 1 1 1 0 Negative regulator of p53/TP53 SMP_LBD PF17047.5 KFM25855.1 - 0.26 10.7 0.5 15 5.0 0.1 2.2 2 0 0 2 2 2 0 Synaptotagmin-like mitochondrial-lipid-binding domain S6PP PF05116.13 KFM25856.1 - 3.1e-69 233.2 0.0 3.8e-69 232.9 0.0 1.1 1 0 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.12 KFM25856.1 - 3.4e-14 53.2 0.0 5.2e-11 42.8 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.16 KFM25856.1 - 0.042 13.0 0.0 0.086 12.0 0.0 1.5 1 0 0 1 1 1 0 Trehalose-phosphatase Golgin_A5 PF09787.9 KFM25857.1 - 0.15 11.5 14.9 0.14 11.6 1.3 2.3 2 0 0 2 2 2 0 Golgin subfamily A member 5 ADIP PF11559.8 KFM25857.1 - 0.34 11.0 2.0 3.9 7.6 0.0 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4407 PF14362.6 KFM25857.1 - 0.35 10.2 16.2 0.78 9.0 16.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 KFM25857.1 - 0.58 9.0 5.2 1 8.2 5.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein GOLGA2L5 PF15070.6 KFM25857.1 - 4.5 5.8 9.3 6.6 5.3 9.3 1.2 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 TMF_TATA_bd PF12325.8 KFM25857.1 - 6.2 7.1 8.6 0.42 10.8 1.5 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding polyprenyl_synt PF00348.17 KFM25858.1 - 7.2e-57 192.4 0.0 9.7e-57 191.9 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Pentapeptide_2 PF01469.18 KFM25858.1 - 5.9e-08 32.5 17.9 1.1e-07 31.5 17.9 1.4 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) DIE2_ALG10 PF04922.12 KFM25859.1 - 8e-100 334.9 0.1 1.3e-99 334.2 0.1 1.3 1 1 0 1 1 1 1 DIE2/ALG10 family Gaa1 PF04114.14 KFM25859.1 - 0.24 10.3 4.6 0.41 9.6 4.6 1.3 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component Sedlin_N PF04628.13 KFM25860.1 - 9.4e-12 45.2 0.0 1.1e-11 45.0 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 KFM25860.1 - 0.0054 16.7 0.0 0.0061 16.5 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family CTP_transf_like PF01467.26 KFM25861.1 - 4.5e-35 120.9 0.0 1.5e-18 67.3 0.0 2.8 2 1 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 KFM25861.1 - 0.00025 21.0 0.0 1.6 8.6 0.1 3.2 3 0 0 3 3 3 2 FAD synthetase ACCA PF03255.14 KFM25862.1 - 3.4e-58 195.6 0.1 9.3e-58 194.2 0.1 1.8 2 0 0 2 2 2 1 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DEAD PF00270.29 KFM25862.1 - 6.7e-47 159.5 0.0 1.1e-46 158.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM25862.1 - 4.9e-33 113.8 0.0 1.4e-31 109.1 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Carboxyl_trans PF01039.22 KFM25862.1 - 6e-12 45.0 0.1 1e-11 44.2 0.1 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 KFM25862.1 - 0.019 14.4 0.1 0.048 13.1 0.0 1.6 2 0 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) Med9 PF07544.13 KFM25862.1 - 0.1 12.7 0.5 0.25 11.4 0.5 1.6 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 ERCC3_RAD25_C PF16203.5 KFM25862.1 - 0.1 11.8 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase CBM53 PF16760.5 KFM25863.1 - 3.2e-38 130.2 0.0 1.7e-11 44.6 0.0 3.6 3 0 0 3 3 3 3 Starch/carbohydrate-binding module (family 53) Glyco_transf_5 PF08323.11 KFM25863.1 - 9.4e-36 123.7 5.6 3.8e-34 118.5 3.0 2.8 2 1 0 2 2 2 1 Starch synthase catalytic domain Glyco_transf_4 PF13439.6 KFM25863.1 - 2.3e-10 40.8 1.4 1.1e-09 38.6 1.4 2.2 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 KFM25863.1 - 6.4e-08 32.3 0.0 3.4e-07 30.0 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KFM25863.1 - 6.9e-06 26.5 0.0 2.3e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KFM25863.1 - 0.0014 19.0 6.6 0.0014 19.0 6.6 5.3 4 2 1 5 5 5 1 Glycosyl transferase 4-like domain MMR_HSR1 PF01926.23 KFM25865.1 - 1.4e-21 76.7 0.0 1.8e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP1_OBG PF01018.22 KFM25865.1 - 1.3e-11 44.3 3.5 1.4e-09 37.7 2.8 2.9 2 1 0 2 2 2 1 GTP1/OBG FeoB_N PF02421.18 KFM25865.1 - 3.2e-09 36.5 0.0 2.5e-08 33.6 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KFM25865.1 - 0.0073 16.4 0.0 1.3 9.0 0.0 2.1 2 0 0 2 2 2 2 Dynamin family MeaB PF03308.16 KFM25865.1 - 0.14 11.2 0.0 1.2 8.1 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 KFM25865.1 - 0.22 12.1 0.0 0.33 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Methyltransf_28 PF02636.17 KFM25866.1 - 4.2e-24 85.6 0.0 2e-13 50.6 0.0 2.1 1 1 1 2 2 2 2 Putative S-adenosyl-L-methionine-dependent methyltransferase LSM PF01423.22 KFM25867.1 - 5.7e-16 58.0 0.2 6.7e-16 57.7 0.2 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KFM25867.1 - 0.0019 17.8 0.0 0.0029 17.2 0.0 1.3 1 0 0 1 1 1 1 Hfq protein RNase_T PF00929.24 KFM25868.1 - 3.7e-11 43.9 0.0 4.9e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Exonuclease COPI_assoc PF08507.10 KFM25869.1 - 0.0099 15.9 2.2 0.015 15.4 2.2 1.4 1 1 0 1 1 1 1 COPI associated protein IKI3 PF04762.12 KFM25870.1 - 2.2e-98 330.5 0.0 1.9e-59 201.7 0.0 3.1 2 1 1 3 3 3 3 IKI3 family ANAPC4_WD40 PF12894.7 KFM25870.1 - 5.8e-05 23.3 0.0 2.6 8.4 0.0 4.3 2 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain CPDase PF07823.11 KFM25871.1 - 4.5e-18 65.7 0.0 1.6e-17 63.9 0.0 1.9 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 KFM25871.1 - 3.1e-07 30.4 0.0 3.6e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 KFM25871.1 - 0.00066 19.8 0.0 0.041 14.1 0.0 2.3 2 0 0 2 2 2 1 LigT like Phosphoesterase DsbD PF02683.15 KFM25872.1 - 9.9e-40 136.7 15.0 1.3e-39 136.3 15.0 1.1 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region TraT PF05818.12 KFM25872.1 - 2.4 7.8 6.2 5.2 6.7 6.2 1.5 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein E1-E2_ATPase PF00122.20 KFM25872.1 - 2.7 7.5 6.1 3.2 7.2 1.7 2.3 2 0 0 2 2 2 0 E1-E2 ATPase B3 PF02362.21 KFM25874.1 - 3.1e-11 43.0 0.0 4.6e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 B3 DNA binding domain DUF4813 PF16072.5 KFM25874.1 - 0.0078 15.9 7.0 0.012 15.3 7.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4813) PRIMA1 PF16101.5 KFM25874.1 - 0.87 9.6 7.0 1.8 8.6 7.0 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 KFM25874.1 - 3.7 6.9 9.4 0.19 11.2 3.5 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal AMP-binding PF00501.28 KFM25875.1 - 1.6e-86 290.6 0.0 2e-86 290.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFM25875.1 - 1e-20 74.5 0.3 1.9e-20 73.6 0.3 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF2781 PF10914.8 KFM25876.1 - 4.3e-33 114.8 13.0 5e-33 114.6 13.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) eIF2A PF08662.11 KFM25877.1 - 7.7e-45 153.2 0.0 5.8e-43 147.0 0.0 3.1 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 KFM25877.1 - 3.8e-09 36.7 0.2 0.66 10.3 0.0 5.3 2 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain RRM_1 PF00076.22 KFM25877.1 - 3.8e-06 26.6 0.0 8.7e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IKI3 PF04762.12 KFM25877.1 - 0.0068 14.5 0.3 0.055 11.5 0.3 2.2 1 1 0 1 1 1 1 IKI3 family WD40 PF00400.32 KFM25877.1 - 0.023 15.5 0.3 68 4.6 0.0 4.7 5 0 0 5 5 5 0 WD domain, G-beta repeat SMC_N PF02463.19 KFM25878.1 - 4.7e-22 78.5 0.0 6.9e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KFM25878.1 - 4.2e-12 47.0 0.1 4.2e-12 47.0 0.1 3.3 3 1 0 3 3 3 1 AAA domain AAA_15 PF13175.6 KFM25878.1 - 1.3e-06 28.4 0.0 2e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KFM25878.1 - 0.00019 21.1 0.0 0.00039 20.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KFM25878.1 - 0.00025 20.9 0.0 0.044 13.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system MukB PF04310.12 KFM25878.1 - 0.0012 18.7 0.1 0.0089 15.9 0.1 2.4 1 1 0 1 1 1 1 MukB N-terminal SMC_hinge PF06470.13 KFM25878.1 - 0.018 15.3 0.0 0.058 13.7 0.0 1.9 1 0 0 1 1 1 0 SMC proteins Flexible Hinge Domain Cep57_MT_bd PF06657.13 KFM25878.1 - 0.029 14.8 1.3 0.26 11.8 0.1 3.0 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 ABC_tran PF00005.27 KFM25878.1 - 0.54 10.8 2.7 6.4 7.3 0.0 3.6 3 1 0 3 3 3 0 ABC transporter AAA_27 PF13514.6 KFM25878.1 - 0.65 9.6 0.0 0.65 9.6 0.0 4.5 4 0 0 4 4 4 0 AAA domain FlaC_arch PF05377.11 KFM25878.1 - 1.5 9.3 3.3 61 4.1 0.2 3.6 4 0 0 4 4 3 0 Flagella accessory protein C (FlaC) DUF1043 PF06295.12 KFM25878.1 - 4 7.4 7.1 5.2 7.1 5.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Spc7 PF08317.11 KFM25878.1 - 6.6 5.5 34.0 0.67 8.8 10.2 3.7 2 1 1 3 3 3 0 Spc7 kinetochore protein Pkinase PF00069.25 KFM25880.1 - 5.9e-46 157.0 0.0 9.3e-46 156.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM25880.1 - 1.4e-34 119.6 0.0 1.9e-34 119.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFM25880.1 - 0.0058 15.4 0.0 0.0082 15.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFM25880.1 - 0.0088 15.4 0.0 0.026 13.8 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFM25880.1 - 0.19 11.0 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family bZIP_1 PF00170.21 KFM25881.1 - 0.018 15.2 4.7 0.018 15.2 4.7 1.8 2 0 0 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.15 KFM25881.1 - 0.57 10.3 12.5 0.063 13.4 8.1 1.7 2 0 0 2 2 2 0 Basic region leucine zipper Rtt106 PF08512.12 KFM25882.1 - 6.9e-18 64.9 0.0 1.4e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 Histone chaperone Rttp106-like PQQ_3 PF13570.6 KFM25883.1 - 0.11 13.0 0.9 1.6 9.3 0.3 2.9 2 0 0 2 2 2 0 PQQ-like domain Ras PF00071.22 KFM25884.1 - 5.9e-49 165.8 0.1 7.2e-49 165.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM25884.1 - 2e-34 118.4 0.0 3e-34 117.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM25884.1 - 1e-16 60.9 0.0 1.2e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFM25884.1 - 1.3e-07 31.2 0.0 1.7e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KFM25884.1 - 1.3e-05 24.7 0.0 1.9e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit cobW PF02492.19 KFM25884.1 - 0.00035 20.2 0.2 0.31 10.6 0.0 2.2 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 KFM25884.1 - 0.00039 20.0 0.0 0.005 16.4 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFM25884.1 - 0.00047 20.2 0.0 0.00071 19.6 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase TsaE PF02367.17 KFM25884.1 - 0.0012 18.8 0.0 0.0025 17.8 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP_bind_1 PF03029.17 KFM25884.1 - 0.0017 18.2 0.1 0.52 10.0 0.0 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 KFM25884.1 - 0.007 16.8 0.1 0.0076 16.6 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KFM25884.1 - 0.0084 16.0 0.3 0.75 9.7 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_5 PF07728.14 KFM25884.1 - 0.0087 16.1 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 KFM25884.1 - 0.012 15.6 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain PduV-EutP PF10662.9 KFM25884.1 - 0.018 14.8 0.1 0.052 13.3 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 KFM25884.1 - 0.02 14.8 0.1 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 NTPase ABC_tran PF00005.27 KFM25884.1 - 0.026 15.1 0.0 0.031 14.8 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KFM25884.1 - 0.029 14.6 0.1 0.067 13.5 0.1 1.5 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 KFM25884.1 - 0.03 13.5 0.4 0.16 11.1 0.2 1.7 1 1 1 2 2 2 0 G-protein alpha subunit TniB PF05621.11 KFM25884.1 - 0.032 13.6 0.0 0.056 12.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_7 PF12775.7 KFM25884.1 - 0.074 12.6 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region MobB PF03205.14 KFM25884.1 - 0.08 12.8 0.0 0.15 11.9 0.0 1.5 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.6 KFM25884.1 - 0.12 12.5 0.1 0.3 11.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain Cu-oxidase_3 PF07732.15 KFM25885.1 - 5.3e-24 84.5 0.6 4.4e-10 39.6 0.0 4.9 4 0 0 4 4 4 4 Multicopper oxidase Cu-oxidase_2 PF07731.14 KFM25885.1 - 8.9e-18 64.4 11.0 3.5e-10 39.8 4.6 5.6 4 1 0 4 4 4 4 Multicopper oxidase Aa_trans PF01490.18 KFM25886.1 - 3.9e-51 174.0 16.8 4.8e-51 173.8 16.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3098 PF11297.8 KFM25886.1 - 8.2 6.1 6.3 1.3 8.7 0.1 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF3098) SecE PF00584.20 KFM25887.1 - 2.1e-11 43.6 0.1 2.3e-11 43.4 0.1 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex NHR2 PF08788.11 KFM25887.1 - 0.044 13.5 0.1 0.057 13.2 0.1 1.1 1 0 0 1 1 1 0 NHR2 domain like CPBP PF02517.16 KFM25888.1 - 1.1e-15 57.7 1.2 2.2e-15 56.8 1.2 1.6 1 1 0 1 1 1 1 CPBP intramembrane metalloprotease K1 PF02960.14 KFM25889.1 - 0.073 13.2 0.1 0.088 12.9 0.1 1.1 1 0 0 1 1 1 0 K1 glycoprotein Ribosomal_L17 PF01196.19 KFM25890.1 - 1.1e-31 109.6 0.0 1.4e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L17 Sld7_C PF18596.1 KFM25890.1 - 0.074 13.2 0.3 0.58 10.3 0.2 2.1 1 1 1 2 2 2 0 Sld7 C-terminal domain Cyclin_N PF00134.23 KFM25891.1 - 1.4e-09 37.7 0.0 7.5e-09 35.4 0.0 2.1 2 1 0 2 2 2 1 Cyclin, N-terminal domain Chon_Sulph_att PF06566.11 KFM25891.1 - 0.018 15.0 5.4 0.029 14.2 5.4 1.3 1 0 0 1 1 1 0 Chondroitin sulphate attachment domain tRNA_int_endo PF01974.17 KFM25893.1 - 8.7e-18 64.2 0.0 1.4e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain RRM_1 PF00076.22 KFM25894.1 - 2.1e-28 97.9 0.0 2.2e-13 49.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFM25894.1 - 2.5e-06 27.1 0.0 0.069 12.8 0.0 2.1 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KFM25894.1 - 0.0017 18.4 0.3 0.088 12.9 0.0 2.2 2 0 0 2 2 2 1 Limkain b1 Nup35_RRM_2 PF14605.6 KFM25894.1 - 0.002 18.1 0.0 0.51 10.4 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.11 KFM25894.1 - 0.011 15.7 0.0 0.16 12.0 0.0 2.1 2 0 0 2 2 2 0 RNA binding domain DbpA PF03880.15 KFM25894.1 - 0.064 13.2 0.0 0.17 11.9 0.0 1.7 2 0 0 2 2 2 0 DbpA RNA binding domain SET_assoc PF11767.8 KFM25894.1 - 0.066 12.9 0.7 2.3 8.0 0.1 2.3 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated HA2 PF04408.23 KFM25895.1 - 3.3e-15 56.3 0.0 5.6e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KFM25895.1 - 2.1e-12 47.2 0.0 3.2e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KFM25895.1 - 7e-06 25.9 0.0 1.2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KFM25895.1 - 7.5e-06 26.3 0.2 3.1e-05 24.2 0.1 2.0 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 KFM25895.1 - 0.011 14.8 0.2 0.022 13.8 0.1 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_16 PF13191.6 KFM25895.1 - 0.031 14.7 0.0 0.075 13.4 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 KFM25895.1 - 0.035 14.4 0.0 0.064 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KFM25895.1 - 0.069 12.9 0.1 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KFM25895.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AOX PF01786.17 KFM25896.1 - 1.5e-91 305.8 0.1 1.7e-91 305.6 0.1 1.1 1 0 0 1 1 1 1 Alternative oxidase TK PF00265.18 KFM25898.1 - 4.5e-43 147.2 0.0 5.2e-43 147.0 0.0 1.0 1 0 0 1 1 1 1 Thymidine kinase tRNA_bind PF01588.20 KFM25899.1 - 1.8e-31 108.1 0.2 3e-31 107.4 0.2 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C PF00043.25 KFM25899.1 - 1.4e-05 25.2 0.7 3.7e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFM25899.1 - 2.5e-05 24.2 0.2 5e-05 23.2 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFM25899.1 - 0.00044 20.4 0.0 0.001 19.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KFM25899.1 - 0.087 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain zf-Tim10_DDP PF02953.15 KFM25900.1 - 1.8e-26 91.5 1.7 2.2e-26 91.3 1.7 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Ank_2 PF12796.7 KFM25901.1 - 2.5e-17 63.2 0.1 2.7e-09 37.5 0.0 3.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFM25901.1 - 5e-17 61.7 5.6 1.4e-06 28.5 0.7 5.1 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM25901.1 - 1.9e-16 58.5 5.9 0.012 16.1 0.1 6.5 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 KFM25901.1 - 2.5e-16 59.8 0.3 1.1e-06 29.1 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KFM25901.1 - 3.9e-15 55.5 8.2 0.00058 20.2 0.1 4.9 4 0 0 4 4 4 3 Ankyrin repeat zf-C3HC4_3 PF13920.6 KFM25901.1 - 1.8e-09 37.3 4.5 1.8e-09 37.3 4.5 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM25901.1 - 3.7e-05 24.0 6.8 3.7e-05 24.0 6.8 2.2 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 KFM25901.1 - 6e-05 22.8 5.6 6e-05 22.8 5.6 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFM25901.1 - 9.6e-05 22.2 6.1 9.6e-05 22.2 6.1 2.3 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KFM25901.1 - 0.02 14.9 7.6 0.02 14.9 7.6 2.4 3 1 0 3 3 3 0 zinc-RING finger domain Dak2 PF02734.17 KFM25901.1 - 0.11 12.4 1.4 0.35 10.7 0.1 2.3 2 1 0 2 2 2 0 DAK2 domain Baculo_IE-1 PF05290.11 KFM25901.1 - 1.9 8.4 4.2 0.49 10.3 0.9 1.6 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-RING_10 PF16685.5 KFM25901.1 - 3.5 7.8 6.1 4.6 7.5 3.8 2.3 3 0 0 3 3 3 0 zinc RING finger of MSL2 AMP-binding PF00501.28 KFM25904.1 - 3.3e-90 302.7 0.0 4.8e-90 302.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme TPP_enzyme_N PF02776.18 KFM25904.1 - 8.7e-34 116.6 0.6 4.4e-33 114.3 0.2 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain AMP-binding_C PF13193.6 KFM25904.1 - 1.6e-16 61.1 2.6 1.9e-16 60.8 0.3 2.5 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain TPP_enzyme_C PF02775.21 KFM25904.1 - 3.6e-16 59.3 0.6 3e-11 43.3 0.1 3.1 1 1 1 2 2 2 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KFM25904.1 - 1.1e-15 57.5 0.0 1.7e-14 53.7 0.0 2.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain GH3 PF03321.13 KFM25904.1 - 0.025 13.5 0.0 0.086 11.7 0.0 1.7 2 0 0 2 2 2 0 GH3 auxin-responsive promoter Zip PF02535.22 KFM25905.1 - 1.2e-54 185.7 14.1 6.5e-54 183.4 14.1 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter DUF3754 PF12576.8 KFM25905.1 - 3.9 7.4 6.0 16 5.5 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3754) Fuseless PF15993.5 KFM25906.1 - 9.9e-06 24.9 0.4 1e-05 24.9 0.4 1.2 1 0 0 1 1 1 1 Fuseless SAP30_Sin3_bdg PF13867.6 KFM25908.1 - 2e-12 47.2 0.1 3.5e-12 46.5 0.0 1.4 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 H_PPase PF03030.16 KFM25909.1 - 3.1e-251 835.6 29.3 4e-251 835.3 29.3 1.1 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase Peptidase_M1 PF01433.20 KFM25909.1 - 2e-36 125.6 0.0 3.3e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KFM25909.1 - 2.6e-15 57.1 0.0 4.7e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Rxt3 PF08642.10 KFM25911.1 - 1.7e-13 51.5 0.6 4.2e-13 50.2 0.3 1.7 1 1 0 1 1 1 1 Histone deacetylation protein Rxt3 Ig_5 PF16681.5 KFM25911.1 - 0.065 13.6 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain LCCL PF03815.19 KFM25911.1 - 0.21 11.7 0.0 0.4 10.8 0.0 1.4 1 0 0 1 1 1 0 LCCL domain ThylakoidFormat PF11264.8 KFM25912.1 - 3.4e-59 200.1 0.0 4.2e-59 199.9 0.0 1.1 1 0 0 1 1 1 1 Thylakoid formation protein PK PF00224.21 KFM25913.1 - 6.9e-65 219.2 0.0 1.1e-64 218.5 0.0 1.3 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KFM25913.1 - 2.5e-19 69.7 0.4 8.3e-19 67.9 0.4 1.9 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain Proteasome PF00227.26 KFM25914.1 - 2.1e-47 161.1 0.1 2.5e-47 160.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF3466 PF11949.8 KFM25914.1 - 0.1 11.2 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3466) Clat_adaptor_s PF01217.20 KFM25915.1 - 5e-18 65.4 1.8 5.7e-18 65.2 1.8 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain AP-5_subunit_s1 PF15001.6 KFM25915.1 - 0.13 12.3 0.5 0.2 11.6 0.3 1.3 1 1 0 1 1 1 0 AP-5 complex subunit sigma-1 NAD_kinase PF01513.21 KFM25916.1 - 2.3e-55 187.8 0.1 1.3e-42 146.1 0.0 2.0 2 0 0 2 2 2 2 ATP-NAD kinase DUF2838 PF10998.8 KFM25918.1 - 1e-14 54.7 0.6 2.8e-14 53.3 0.6 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2838) Gpi16 PF04113.14 KFM25919.1 - 1.3e-29 103.2 0.0 5.4e-20 71.4 0.0 2.0 2 0 0 2 2 2 2 Gpi16 subunit, GPI transamidase component AAA_16 PF13191.6 KFM25920.1 - 7.3e-07 29.7 0.0 4.3e-06 27.2 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KFM25920.1 - 5.5e-06 26.8 0.0 1e-05 26.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KFM25920.1 - 5.5e-05 23.0 0.1 0.00031 20.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 KFM25920.1 - 9.7e-05 22.3 0.1 0.14 12.0 0.0 2.7 3 0 0 3 3 2 2 NTPase AAA_22 PF13401.6 KFM25920.1 - 0.0002 21.6 0.0 0.0022 18.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KFM25920.1 - 0.0018 18.8 0.0 0.0045 17.5 0.0 1.8 2 0 0 2 2 1 1 AAA domain CbiA PF01656.23 KFM25920.1 - 0.002 18.2 0.0 0.0039 17.3 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Viral_helicase1 PF01443.18 KFM25920.1 - 0.0026 17.5 0.0 0.0055 16.5 0.0 1.5 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.14 KFM25920.1 - 0.0026 17.7 0.0 0.014 15.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KFM25920.1 - 0.0033 17.0 0.0 0.0054 16.3 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_33 PF13671.6 KFM25920.1 - 0.0062 16.7 0.1 0.03 14.5 0.0 2.2 3 0 0 3 3 2 1 AAA domain SRP54 PF00448.22 KFM25920.1 - 0.012 15.2 0.0 0.034 13.8 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_25 PF13481.6 KFM25920.1 - 0.013 15.1 0.0 0.44 10.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 KFM25920.1 - 0.014 14.8 0.0 0.27 10.6 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein AAA_24 PF13479.6 KFM25920.1 - 0.015 15.0 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 KFM25920.1 - 0.016 15.4 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain Zeta_toxin PF06414.12 KFM25920.1 - 0.016 14.5 0.0 0.041 13.2 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin TrwB_AAD_bind PF10412.9 KFM25920.1 - 0.019 13.9 0.1 0.055 12.4 0.0 1.6 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain KTI12 PF08433.10 KFM25920.1 - 0.019 14.4 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_19 PF13245.6 KFM25920.1 - 0.021 15.2 0.0 0.11 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KFM25920.1 - 0.023 14.6 0.0 0.061 13.2 0.0 1.7 1 1 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 KFM25920.1 - 0.028 14.8 0.0 0.065 13.6 0.0 1.6 2 0 0 2 2 1 0 RNA helicase Rad17 PF03215.15 KFM25920.1 - 0.033 14.1 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 KFM25920.1 - 0.037 14.1 0.0 0.097 12.8 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_31 PF13614.6 KFM25920.1 - 0.038 13.9 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KFM25920.1 - 0.046 13.5 0.2 0.5 10.1 0.0 2.0 1 1 1 2 2 2 0 AAA domain ATPase_2 PF01637.18 KFM25920.1 - 0.052 13.5 0.0 0.098 12.6 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_3 PF07726.11 KFM25920.1 - 0.076 12.9 0.0 0.21 11.4 0.0 1.8 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 KFM25920.1 - 0.076 13.1 0.0 0.21 11.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) RsgA_GTPase PF03193.16 KFM25920.1 - 0.081 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase Mg_chelatase PF01078.21 KFM25920.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KFM25920.1 - 0.12 12.6 0.0 0.47 10.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 KFM25920.1 - 0.13 11.8 0.1 0.37 10.4 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain CBP_BcsQ PF06564.12 KFM25920.1 - 0.19 11.2 0.2 0.57 9.6 0.0 1.7 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ HR_lesion PF05514.11 KFM25922.1 - 2.1e-25 89.5 4.0 2.3e-25 89.4 4.0 1.0 1 0 0 1 1 1 1 HR-like lesion-inducing DoxX PF07681.12 KFM25922.1 - 2.1e-07 31.4 4.3 2.1e-07 31.4 4.3 2.1 2 1 0 2 2 2 1 DoxX SURF4 PF02077.15 KFM25922.1 - 0.00025 20.8 5.8 0.0018 17.9 1.7 2.3 2 0 0 2 2 2 2 SURF4 family CLASP_N PF12348.8 KFM25923.1 - 1.5e-13 50.9 0.3 3.9e-11 42.9 0.2 2.2 2 0 0 2 2 2 2 CLASP N terminal GATA PF00320.27 KFM25924.1 - 1e-10 41.0 2.7 2.2e-10 39.9 2.7 1.6 1 0 0 1 1 1 1 GATA zinc finger Mon1 PF03164.14 KFM25925.1 - 7.6e-32 110.9 0.0 3.7e-23 82.3 0.0 3.0 1 1 1 3 3 3 3 Trafficking protein Mon1 CBS PF00571.28 KFM25926.1 - 2.7e-16 59.7 0.2 3.3e-16 59.5 0.2 1.1 1 0 0 1 1 1 1 CBS domain BolA PF01722.18 KFM25927.1 - 1.1e-16 60.9 0.0 1.3e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein Cohesin_HEAT PF12765.7 KFM25927.1 - 0.1 12.9 0.1 0.17 12.2 0.1 1.3 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion DUF1995 PF09353.10 KFM25928.1 - 2.7e-19 70.0 0.0 3.5e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) zf-CCHC_4 PF14392.6 KFM25928.1 - 0.0014 18.3 5.1 0.14 11.9 0.2 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-C2H2_10 PF16588.5 KFM25928.1 - 0.47 10.2 0.1 0.47 10.2 0.1 2.4 2 0 0 2 2 2 0 C2H2 zinc-finger zf-CCHC_2 PF13696.6 KFM25928.1 - 1.4 8.8 12.8 4.2 7.3 4.9 2.5 2 0 0 2 2 2 0 Zinc knuckle Mem_trans PF03547.18 KFM25929.1 - 4.7e-05 22.0 15.2 0.087 11.2 0.3 3.2 3 0 0 3 3 3 3 Membrane transport protein Brix PF04427.18 KFM25930.1 - 8.1e-43 146.8 0.0 1.1e-42 146.3 0.0 1.1 1 0 0 1 1 1 1 Brix domain Herpes_UL36 PF03586.13 KFM25930.1 - 0.029 13.7 0.0 0.054 12.8 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL36 tegument protein S10_plectin PF03501.15 KFM25931.1 - 7.2e-40 135.0 0.1 8.6e-40 134.7 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain FYRC PF05965.14 KFM25932.1 - 3e-19 68.9 0.0 6.6e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.14 KFM25932.1 - 1.7e-05 24.5 0.0 3.1e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 F/Y-rich N-terminus U-box PF04564.15 KFM25932.1 - 2e-05 24.7 0.0 4e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 U-box domain GlutR_dimer PF00745.20 KFM25932.1 - 0.14 12.6 0.7 0.29 11.6 0.7 1.5 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain GDA1_CD39 PF01150.17 KFM25933.1 - 1.4e-49 168.9 0.0 1.9e-49 168.5 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DnaJ PF00226.31 KFM25934.1 - 0.035 14.2 0.0 0.063 13.4 0.0 1.5 1 1 0 1 1 1 0 DnaJ domain SapB_1 PF05184.15 KFM25935.1 - 2.8e-15 56.0 2.1 4.1e-07 29.9 0.9 3.8 3 0 0 3 3 3 3 Saposin-like type B, region 1 SapB_2 PF03489.17 KFM25935.1 - 1.1e-14 54.2 8.8 2.9e-09 36.9 0.7 3.8 3 0 0 3 3 3 3 Saposin-like type B, region 2 TetR_C_15 PF17918.1 KFM25935.1 - 0.099 13.4 1.0 12 6.7 0.0 3.0 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Phospholip_B PF04916.13 KFM25936.1 - 1.7e-84 284.3 0.0 1e-62 212.4 0.0 3.0 1 1 2 3 3 3 3 Phospholipase B SBP PF03110.14 KFM25938.1 - 1.4e-22 79.7 5.4 2.2e-22 79.1 5.4 1.2 1 0 0 1 1 1 1 SBP domain Aldedh PF00171.22 KFM25939.1 - 1.9e-37 128.9 0.0 2.5e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family UPF0561 PF10573.9 KFM25940.1 - 0.0019 18.3 2.9 0.0019 18.3 2.9 2.8 1 1 1 2 2 2 1 Uncharacterised protein family UPF0561 DAP_epimerase PF01678.19 KFM25941.1 - 2.3e-59 198.9 0.0 2.6e-32 111.6 0.0 2.1 2 0 0 2 2 2 2 Diaminopimelate epimerase GSDH PF07995.11 KFM25942.1 - 1.6e-09 37.5 0.2 1.1e-07 31.5 0.0 3.4 3 1 0 3 3 3 1 Glucose / Sorbosone dehydrogenase SGL PF08450.12 KFM25942.1 - 0.029 14.0 0.1 0.67 9.5 0.1 2.2 1 1 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region Ephrin_rec_like PF07699.13 KFM25942.1 - 0.14 12.0 0.3 0.29 10.9 0.3 1.5 1 0 0 1 1 1 0 Putative ephrin-receptor like GCS2 PF04107.13 KFM25943.1 - 1.6e-79 267.3 0.0 2.9e-79 266.5 0.0 1.3 1 0 0 1 1 1 1 Glutamate-cysteine ligase family 2(GCS2) Helicase_C PF00271.31 KFM25943.1 - 1.5e-28 99.3 0.0 4.1e-28 98.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFM25943.1 - 4.2e-17 62.5 0.0 2.8e-08 33.7 0.0 2.5 1 1 1 2 2 2 2 DEAD/DEAH box helicase GUCT PF08152.12 KFM25943.1 - 1.5e-08 34.8 0.0 3.5e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 GUCT (NUC152) domain ERCC3_RAD25_C PF16203.5 KFM25943.1 - 0.05 12.8 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Acid_PPase PF12689.7 KFM25945.1 - 1.2e-27 96.9 0.0 1.9e-15 57.1 0.0 2.0 1 1 1 2 2 2 2 Acid Phosphatase PsaN PF05479.11 KFM25946.1 - 1.9e-33 115.5 0.3 2e-33 115.4 0.3 1.0 1 0 0 1 1 1 1 Photosystem I reaction centre subunit N (PSAN or PSI-N) NAD_binding_10 PF13460.6 KFM25948.1 - 4.6e-25 88.6 0.1 7.1e-25 88.0 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KFM25948.1 - 3.8e-18 65.9 0.0 5e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KFM25948.1 - 1.9e-11 43.9 0.1 3.9e-11 42.9 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KFM25948.1 - 2.2e-05 24.4 0.1 3.4e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KFM25948.1 - 4.9e-05 22.9 0.0 6.9e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KFM25948.1 - 0.00016 20.9 0.2 0.00094 18.4 0.1 2.1 2 1 0 2 2 2 1 RmlD substrate binding domain adh_short PF00106.25 KFM25948.1 - 0.00027 20.5 0.1 0.00041 19.9 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.19 KFM25948.1 - 0.00044 19.3 0.0 0.00058 18.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short_C2 PF13561.6 KFM25948.1 - 0.0033 17.0 0.3 0.0052 16.4 0.3 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Semialdhyde_dh PF01118.24 KFM25948.1 - 0.0091 16.4 0.0 0.016 15.6 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 KFM25948.1 - 0.095 11.8 0.1 0.17 11.0 0.1 1.4 1 0 0 1 1 1 0 Male sterility protein Aa_trans PF01490.18 KFM25949.1 - 6.8e-47 160.1 4.5 8.9e-47 159.7 4.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KFM25949.1 - 0.0019 17.4 11.2 0.0019 17.4 11.2 1.4 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family HMG_box_2 PF09011.10 KFM25950.1 - 0.011 16.3 1.3 0.026 15.1 1.3 1.7 1 0 0 1 1 1 0 HMG-box domain HMG_box PF00505.19 KFM25950.1 - 0.065 13.7 2.2 0.19 12.2 2.2 1.9 1 1 0 1 1 1 0 HMG (high mobility group) box MRI PF15325.6 KFM25950.1 - 2.5 9.2 5.2 6 8.0 5.2 1.7 1 0 0 1 1 1 0 Modulator of retrovirus infection RNA_pol_L_2 PF13656.6 KFM25951.1 - 4.7e-09 35.9 0.0 7.4e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KFM25951.1 - 0.042 13.3 0.0 0.15 11.5 0.0 1.8 2 0 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain MBOAT PF03062.19 KFM25953.1 - 2.9e-34 118.9 8.0 3e-33 115.6 8.0 2.0 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family ABC2_membrane PF01061.24 KFM25954.1 - 3.9e-65 219.2 51.2 5e-45 153.5 24.2 3.1 4 0 0 4 4 2 2 ABC-2 type transporter ABC_tran PF00005.27 KFM25954.1 - 6.2e-33 114.2 0.0 5.8e-20 72.2 0.0 3.8 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 KFM25954.1 - 2.2e-08 34.3 0.0 0.039 13.8 0.0 3.9 5 0 0 5 5 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFM25954.1 - 9.5e-08 31.7 0.6 0.018 14.8 0.0 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KFM25954.1 - 1.3e-06 28.9 0.3 0.028 14.8 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain ABC2_membrane_3 PF12698.7 KFM25954.1 - 2.1e-06 27.1 47.5 0.00016 21.0 13.9 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein SMC_N PF02463.19 KFM25954.1 - 2.5e-06 27.1 0.4 0.43 10.0 0.0 3.9 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 KFM25954.1 - 1.6e-05 25.1 0.0 0.098 12.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KFM25954.1 - 4.3e-05 23.8 0.7 0.023 15.0 0.0 3.0 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KFM25954.1 - 8e-05 22.6 0.2 0.094 12.6 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 KFM25954.1 - 0.00014 21.7 0.3 0.31 10.7 0.1 2.9 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.6 KFM25954.1 - 0.00029 20.5 6.1 0.0051 16.4 0.0 3.3 3 1 0 3 3 3 1 AAA domain AAA PF00004.29 KFM25954.1 - 0.00073 20.0 0.2 0.58 10.6 0.0 3.5 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KFM25954.1 - 0.002 18.7 0.0 0.9 10.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KFM25954.1 - 0.002 18.7 0.0 0.21 12.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KFM25954.1 - 0.0048 16.8 1.8 1.4 8.8 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.6 KFM25954.1 - 0.0065 16.8 0.4 4.7 7.5 0.4 2.9 4 0 0 4 4 2 1 AAA domain cobW PF02492.19 KFM25954.1 - 0.0085 15.7 0.3 2.8 7.5 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 KFM25954.1 - 0.013 15.5 0.2 7.4 6.7 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.6 KFM25954.1 - 0.029 14.6 0.5 10 6.3 0.3 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KFM25954.1 - 0.058 13.8 0.1 16 6.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase TsaE PF02367.17 KFM25954.1 - 0.069 13.2 0.7 4.2 7.4 0.2 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KFM25954.1 - 0.081 12.6 0.2 10 5.8 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KFM25954.1 - 0.1 12.6 1.6 0.31 11.0 0.1 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 KFM25954.1 - 0.1 12.5 0.1 15 5.5 0.0 2.6 2 1 0 2 2 2 0 Rad17 P-loop domain AAA_7 PF12775.7 KFM25954.1 - 0.2 11.1 0.1 3.6 7.0 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Pox_A32 PF04665.12 KFM25954.1 - 0.21 11.0 0.2 5.8 6.3 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein PDR_assoc PF08370.11 KFM25954.1 - 3.6 7.4 8.1 1.1 9.1 0.2 2.7 2 0 0 2 2 2 0 Plant PDR ABC transporter associated ABC2_membrane PF01061.24 KFM25955.1 - 1.3e-68 230.6 54.3 7e-40 136.7 27.6 3.7 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.27 KFM25955.1 - 4.7e-37 127.5 0.1 3.4e-20 73.0 0.0 3.4 3 0 0 3 3 3 3 ABC transporter AAA_21 PF13304.6 KFM25955.1 - 1e-08 35.4 0.0 0.055 13.3 0.0 4.0 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFM25955.1 - 1.8e-07 30.8 0.8 0.013 15.3 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KFM25955.1 - 1.8e-07 31.7 0.4 0.00036 21.0 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 KFM25955.1 - 7.2e-06 26.2 0.1 0.031 14.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.7 KFM25955.1 - 3.1e-05 23.3 22.1 3.1e-05 23.3 22.1 2.6 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_25 PF13481.6 KFM25955.1 - 0.00011 21.9 0.1 0.016 14.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFM25955.1 - 0.00011 22.0 1.0 0.39 10.4 0.2 2.7 2 0 0 2 2 2 2 AAA domain PDR_CDR PF06422.12 KFM25955.1 - 0.00013 21.8 0.9 0.065 13.1 0.6 3.4 3 0 0 3 3 3 1 CDR ABC transporter PDR_assoc PF08370.11 KFM25955.1 - 0.00017 21.2 7.6 0.00018 21.2 0.2 2.8 2 0 0 2 2 2 1 Plant PDR ABC transporter associated SMC_N PF02463.19 KFM25955.1 - 0.00018 21.0 0.9 4.4 6.7 0.0 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KFM25955.1 - 0.00026 20.9 1.0 0.098 12.6 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 KFM25955.1 - 0.0006 20.4 0.1 0.93 9.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KFM25955.1 - 0.00069 19.9 0.8 0.3 11.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KFM25955.1 - 0.00098 19.5 0.8 0.78 10.2 0.0 3.6 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KFM25955.1 - 0.013 15.9 0.1 3.4 8.1 0.0 3.0 3 0 0 3 3 2 0 RNA helicase AAA_18 PF13238.6 KFM25955.1 - 0.016 15.7 0.1 1.3 9.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KFM25955.1 - 0.021 14.9 0.4 7.4 6.7 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.6 KFM25955.1 - 0.027 14.7 0.6 10 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KFM25955.1 - 0.045 14.1 5.1 4.9 7.5 0.4 3.5 5 0 0 5 5 2 0 AAA domain Rad17 PF03215.15 KFM25955.1 - 0.056 13.4 0.1 3.9 7.3 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain NACHT PF05729.12 KFM25955.1 - 0.059 13.3 6.1 1.5 8.7 0.1 3.0 3 0 0 3 3 2 0 NACHT domain cobW PF02492.19 KFM25955.1 - 0.095 12.3 1.3 3.7 7.1 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 KFM25955.1 - 0.096 12.0 0.2 15 4.8 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin TsaE PF02367.17 KFM25955.1 - 0.11 12.4 0.7 4.7 7.2 0.1 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KFM25955.1 - 0.12 12.1 0.7 11 5.7 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KFM25955.1 - 0.13 11.7 0.2 2.4 7.6 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region NTPase_1 PF03266.15 KFM25955.1 - 0.15 12.0 2.0 20 5.0 0.0 3.2 3 0 0 3 3 3 0 NTPase Ploopntkinase3 PF18751.1 KFM25955.1 - 0.3 11.0 1.0 32 4.4 0.0 2.9 3 0 0 3 3 3 0 P-loop Nucleotide Kinase3 AAA_5 PF07728.14 KFM25955.1 - 0.33 10.9 2.1 0.77 9.8 0.1 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KFM25955.1 - 0.65 9.3 4.7 1.6 8.1 0.2 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI SGT1 PF07093.11 KFM25956.1 - 0.049 12.1 0.0 0.053 12.0 0.0 1.1 1 0 0 1 1 1 0 SGT1 protein SGT1 PF07093.11 KFM25957.1 - 2.8e-65 220.9 0.0 1.7e-35 122.5 0.0 3.0 2 1 1 3 3 3 3 SGT1 protein Glyco_tran_28_C PF04101.16 KFM25959.1 - 8.2e-23 81.2 0.0 1e-22 80.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.18 KFM25959.1 - 3.1e-05 23.0 0.1 4.5e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_1_4 PF13692.6 KFM25959.1 - 0.1 13.1 1.5 0.15 12.4 1.5 1.7 1 1 0 1 1 1 0 Glycosyl transferases group 1 EXOSC1 PF10447.9 KFM25960.1 - 3.5e-13 50.1 0.1 1.9e-07 31.7 0.0 2.2 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 KFM25960.1 - 1.1e-11 44.3 1.3 5.6e-11 42.1 0.4 2.3 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region TRAM PF01938.20 KFM25960.1 - 0.1 12.6 0.0 0.3 11.1 0.0 1.8 2 0 0 2 2 2 0 TRAM domain Ribosomal_L1 PF00687.21 KFM25961.1 - 7.3e-45 153.2 2.4 8.7e-45 153.0 2.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Mod_r PF07200.13 KFM25961.1 - 0.034 14.2 0.3 0.049 13.7 0.3 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein YtxH PF12732.7 KFM25961.1 - 0.06 13.9 0.8 1.1 9.9 0.8 2.4 1 1 0 1 1 1 0 YtxH-like protein Spore_YunB PF09560.10 KFM25961.1 - 0.085 12.9 0.2 0.16 12.0 0.2 1.5 1 0 0 1 1 1 0 Sporulation protein YunB (Spo_YunB) TPR_12 PF13424.6 KFM25962.1 - 2.1e-08 34.3 4.8 6.1e-06 26.4 0.7 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFM25962.1 - 5.7e-06 25.9 1.7 0.0077 16.0 0.6 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFM25962.1 - 1.2e-05 25.1 0.4 0.00088 19.3 0.4 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFM25962.1 - 3.1e-05 23.7 0.4 0.012 15.6 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat SNAP PF14938.6 KFM25962.1 - 0.0033 16.9 0.8 0.014 14.9 0.1 1.9 2 0 0 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_2 PF07719.17 KFM25962.1 - 0.0044 17.0 9.9 0.077 13.1 0.3 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFM25962.1 - 0.013 15.9 2.2 0.11 13.0 0.0 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFM25962.1 - 0.014 16.2 5.8 1.5 9.9 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFM25962.1 - 0.53 10.2 7.3 6.7 6.7 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat HAD_2 PF13419.6 KFM25963.1 - 6.4e-08 32.9 0.0 6.2e-07 29.7 0.0 2.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFM25963.1 - 0.00011 22.2 0.0 0.00027 21.0 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KFM25963.1 - 0.00014 22.2 0.0 0.0028 18.0 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 KFM25963.1 - 0.1 12.4 0.0 0.82 9.5 0.0 2.1 2 0 0 2 2 2 0 Acid Phosphatase DUF4743 PF15916.5 KFM25964.1 - 0.17 11.9 0.1 0.31 11.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4743) FliT PF05400.13 KFM25966.1 - 0.1 13.4 6.3 0.22 12.4 6.3 1.5 1 0 0 1 1 1 0 Flagellar protein FliT VWA_CoxE PF05762.14 KFM25968.1 - 0.036 13.5 0.0 0.063 12.7 0.0 1.4 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein OTU PF02338.19 KFM25969.1 - 3.2e-17 63.2 0.0 4.3e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KFM25969.1 - 0.00051 19.6 0.0 0.7 9.3 0.0 2.2 2 0 0 2 2 2 2 Peptidase C65 Otubain Peptidase_C1 PF00112.23 KFM25970.1 - 7.6e-59 199.4 0.3 1.2e-58 198.8 0.3 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 KFM25970.1 - 8e-10 39.0 0.4 1.6e-09 38.1 0.4 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 KFM25970.1 - 0.002 17.0 0.2 1 8.0 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Methyltr_RsmB-F PF01189.17 KFM25971.1 - 2.8e-71 239.3 0.0 3.9e-71 238.8 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 KFM25971.1 - 7.1e-11 42.5 0.0 2e-10 41.0 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 KFM25971.1 - 0.00011 22.4 0.0 0.00019 21.6 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Met_10 PF02475.16 KFM25971.1 - 0.00052 19.8 0.0 0.00086 19.1 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Ubie_methyltran PF01209.18 KFM25971.1 - 0.027 13.8 0.0 0.046 13.1 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KFM25971.1 - 0.045 13.6 0.0 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_L34e PF01199.18 KFM25972.1 - 3.2e-39 133.1 1.4 5.6e-39 132.4 1.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L34e CRAL_TRIO_2 PF13716.6 KFM25973.1 - 1.9e-13 50.8 0.0 2.6e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 KFM25973.1 - 0.0045 16.7 0.0 2.8 7.6 0.0 2.1 2 0 0 2 2 2 2 CRAL/TRIO domain Transglut_core PF01841.19 KFM25974.1 - 1.3e-11 44.9 0.9 3.5e-11 43.5 0.9 1.8 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.15 KFM25974.1 - 1.4e-09 37.8 0.1 2.5e-09 36.9 0.1 1.3 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Zn_Tnp_IS1595 PF12760.7 KFM25974.1 - 0.0017 18.3 0.2 0.0048 16.9 0.2 1.8 1 0 0 1 1 1 1 Transposase zinc-ribbon domain UreF PF01730.16 KFM25974.1 - 0.11 13.1 3.7 0.32 11.6 0.1 2.4 2 0 0 2 2 2 0 UreF PAW PF04721.17 KFM25974.1 - 1.9 8.2 4.1 1.1 9.0 1.4 1.8 2 0 0 2 2 2 0 PNGase C-terminal domain, mannose-binding module PAW bVLRF1 PF18826.1 KFM25976.1 - 8.2e-45 152.3 0.0 1.4e-44 151.6 0.0 1.3 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor DDRGK PF09756.9 KFM25977.1 - 5.2e-42 143.6 6.2 5.9e-42 143.4 6.2 1.0 1 0 0 1 1 1 1 DDRGK domain LCD1 PF09798.9 KFM25977.1 - 0.0068 15.0 0.0 0.0091 14.6 0.0 1.1 1 0 0 1 1 1 1 DNA damage checkpoint protein FeoC PF09012.10 KFM25977.1 - 0.018 15.1 0.1 1.7 8.8 0.0 2.5 2 0 0 2 2 2 0 FeoC like transcriptional regulator EcoR124_C PF12008.8 KFM25977.1 - 0.043 13.5 2.2 0.053 13.2 2.2 1.1 1 0 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal HTH_DeoR PF08220.12 KFM25977.1 - 0.048 13.4 0.3 0.48 10.2 0.1 2.2 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain BPL_C PF02237.17 KFM25977.1 - 0.093 12.6 0.1 1.1 9.2 0.0 2.3 1 1 1 2 2 2 0 Biotin protein ligase C terminal domain Borrelia_P83 PF05262.11 KFM25977.1 - 0.093 11.2 4.1 0.12 10.9 4.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Dus PF01207.17 KFM25978.1 - 1.1e-59 202.1 0.1 1.8e-59 201.4 0.1 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) MIF4G PF02854.19 KFM25979.1 - 4.6e-36 124.5 0.0 5.8e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 MIF4G domain DUF543 PF04418.12 KFM25979.1 - 3.5e-15 55.8 0.7 1e-13 51.1 0.6 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF543) SOAR PF16533.5 KFM25979.1 - 0.0086 16.0 0.1 0.017 15.1 0.1 1.4 1 0 0 1 1 1 1 STIM1 Orai1-activating region GHMP_kinases_C PF08544.13 KFM25979.1 - 0.022 15.1 4.5 0.1 13.0 0.1 3.9 4 0 0 4 4 4 0 GHMP kinases C terminal eIF_4G1 PF12152.8 KFM25979.1 - 0.15 12.3 0.0 0.37 11.0 0.0 1.7 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4G1 DUF737 PF05300.11 KFM25980.1 - 0.016 15.6 3.0 0.021 15.2 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF737) FAM76 PF16046.5 KFM25980.1 - 0.042 13.2 0.2 0.048 13.0 0.2 1.1 1 0 0 1 1 1 0 FAM76 protein Fez1 PF06818.15 KFM25980.1 - 0.17 12.3 6.8 0.24 11.8 6.8 1.1 1 0 0 1 1 1 0 Fez1 CDO_I PF05995.12 KFM25981.1 - 1.3e-25 89.6 0.0 4.8e-25 87.8 0.0 1.7 1 1 0 1 1 1 1 Cysteine dioxygenase type I DUF5617 PF18493.1 KFM25981.1 - 0.0086 16.2 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5617) Cupin_2 PF07883.11 KFM25981.1 - 0.082 12.6 0.3 1.1 9.1 0.1 2.3 2 0 0 2 2 2 0 Cupin domain Ribosomal_L18p PF00861.22 KFM25982.1 - 2.8e-27 95.4 0.0 3.3e-27 95.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast DUF4922 PF16269.5 KFM25983.1 - 0.023 14.5 0.0 0.098 12.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4922) WD40 PF00400.32 KFM25984.1 - 4.1e-40 135.0 12.1 5.9e-08 33.3 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM25984.1 - 4.6e-17 62.1 0.0 1.4e-08 34.9 0.0 5.4 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFM25984.1 - 0.00011 21.1 0.0 0.27 9.8 0.0 2.7 3 0 0 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.11 KFM25984.1 - 0.00011 22.2 0.0 0.0028 17.6 0.0 2.7 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFM25984.1 - 0.0012 17.9 7.0 0.6 9.0 0.1 4.6 4 2 1 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Kelch_6 PF13964.6 KFM25984.1 - 0.013 15.8 0.0 3.7 8.0 0.0 3.5 4 0 0 4 4 4 0 Kelch motif T2SS-T3SS_pil_N PF13629.6 KFM25984.1 - 0.097 12.4 0.1 1.7 8.4 0.0 2.8 2 0 0 2 2 2 0 Pilus formation protein N terminal region PQQ_3 PF13570.6 KFM25984.1 - 0.33 11.5 16.5 1.1 9.9 0.1 5.3 5 1 1 6 6 6 0 PQQ-like domain PALB2_WD40 PF16756.5 KFM25984.1 - 0.48 9.3 3.0 7.3 5.4 0.6 2.4 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain DUF846 PF05832.12 KFM25985.1 - 0.23 11.5 2.5 0.36 10.9 2.5 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF846) PPR_2 PF13041.6 KFM25986.1 - 4.5e-21 74.8 0.0 3.9e-05 23.8 0.0 7.5 5 2 3 8 8 8 7 PPR repeat family PPR PF01535.20 KFM25986.1 - 2.5e-18 65.0 0.6 0.00087 19.4 0.0 9.1 10 0 0 10 10 10 3 PPR repeat PPR_1 PF12854.7 KFM25986.1 - 3.8e-17 61.7 0.0 8.8e-05 22.1 0.0 6.3 6 0 0 6 6 6 3 PPR repeat PPR_3 PF13812.6 KFM25986.1 - 6.3e-14 51.8 0.0 0.0058 16.7 0.0 6.3 4 2 2 7 7 7 4 Pentatricopeptide repeat domain PPR_long PF17177.4 KFM25986.1 - 3.1e-05 23.4 0.0 0.58 9.5 0.0 3.2 2 2 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 KFM25986.1 - 0.031 15.1 38.4 1.2 10.2 1.3 9.0 5 2 5 10 10 10 0 Tetratricopeptide repeat B12-binding_2 PF02607.17 KFM25986.1 - 0.069 13.6 0.0 9.2 6.8 0.0 3.4 3 0 0 3 3 3 0 B12 binding domain TPR_10 PF13374.6 KFM25986.1 - 0.57 10.1 5.9 11 6.0 0.2 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4093 PF13331.6 KFM25987.1 - 2e-09 37.7 0.0 2.6e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4093) UBA_3 PF09288.10 KFM25987.1 - 0.089 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain FeoA PF04023.14 KFM25987.1 - 0.13 12.6 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 FeoA domain WD40 PF00400.32 KFM25988.1 - 0.00053 20.7 2.7 0.21 12.5 0.0 5.0 6 0 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM25988.1 - 0.00056 20.2 0.0 0.39 11.0 0.0 3.7 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Hexapep PF00132.24 KFM25989.1 - 1.4e-12 46.8 5.1 0.0005 19.7 0.2 4.3 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KFM25989.1 - 6.4e-08 32.2 6.7 1.4e-05 24.7 0.1 4.1 2 2 2 4 4 4 3 Hexapeptide repeat of succinyl-transferase Pkinase PF00069.25 KFM25991.1 - 2.6e-36 125.3 0.0 3.6e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM25991.1 - 6.9e-18 64.9 0.0 9.4e-18 64.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 KFM25991.1 - 0.1 12.2 0.0 4 7.0 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 BssC_TutF PF08201.11 KFM25991.1 - 0.14 12.2 0.1 0.32 11.0 0.1 1.6 1 0 0 1 1 1 0 BssC/TutF protein Asparaginase PF00710.20 KFM25994.1 - 5.3e-56 189.2 0.0 7.7e-56 188.7 0.0 1.1 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KFM25994.1 - 1.1e-18 67.6 0.0 2.1e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain EBP PF05241.12 KFM25996.1 - 6.5e-42 143.0 8.5 8.6e-42 142.6 8.5 1.2 1 0 0 1 1 1 1 Emopamil binding protein DUF2781 PF10914.8 KFM25996.1 - 0.0013 19.1 7.7 0.0019 18.6 7.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) DUF1129 PF06570.11 KFM25996.1 - 0.11 12.0 0.4 0.19 11.2 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) MHYT PF03707.16 KFM25996.1 - 0.12 12.6 3.0 0.35 11.1 3.0 1.8 1 0 0 1 1 1 0 Bacterial signalling protein N terminal repeat MRG PF05712.13 KFM25997.1 - 1.7e-32 112.3 0.2 5.9e-32 110.6 0.2 1.7 1 1 0 1 1 1 1 MRG Tudor-knot PF11717.8 KFM25997.1 - 0.002 18.0 1.1 0.0029 17.5 0.3 1.7 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 KFM25997.1 - 0.1 12.5 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Biotin_lipoyl PF00364.22 KFM25998.1 - 6.4e-18 64.4 2.4 1.2e-17 63.5 2.4 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KFM25998.1 - 3e-07 30.1 0.1 0.00067 19.4 0.0 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like GCV_H PF01597.19 KFM25998.1 - 3.8e-05 23.6 0.5 5.6e-05 23.0 0.5 1.3 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 KFM25998.1 - 0.00012 21.9 0.2 0.00024 21.0 0.2 1.4 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain HlyD_D23 PF16576.5 KFM25998.1 - 0.00053 19.3 0.3 0.11 11.7 0.1 2.2 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion SporV_AA PF12164.8 KFM25998.1 - 0.018 15.4 1.6 0.027 14.8 1.6 1.2 1 0 0 1 1 1 0 Stage V sporulation protein AA HlyD_3 PF13437.6 KFM25998.1 - 0.023 15.4 0.2 0.35 11.6 0.1 2.3 2 0 0 2 2 2 0 HlyD family secretion protein DUF2046 PF09755.9 KFM25998.1 - 0.028 13.6 0.0 0.036 13.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) FAST_1 PF06743.15 KFM25999.1 - 9.8e-07 28.6 3.5 0.0003 20.7 0.0 4.8 3 1 3 6 6 6 2 FAST kinase-like protein, subdomain 1 MTES_1575 PF18741.1 KFM25999.1 - 6.1e-05 23.1 0.0 0.00012 22.1 0.0 1.5 1 0 0 1 1 1 1 REase_MTES_1575 RAP PF08373.10 KFM25999.1 - 0.00046 20.2 0.0 0.0012 18.9 0.0 1.7 1 0 0 1 1 1 1 RAP domain Topo_C_assoc PF14370.6 KFM25999.1 - 0.091 12.7 0.0 0.24 11.3 0.0 1.7 2 0 0 2 2 2 0 C-terminal topoisomerase domain DUF1601 PF07671.11 KFM25999.1 - 3.3 7.7 14.2 5.4 7.0 0.0 4.6 5 1 0 5 5 5 0 Protein of unknown function (DUF1601) Methyltransf_25 PF13649.6 KFM26000.1 - 6.8e-11 42.7 0.0 1.6e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KFM26000.1 - 6.6e-10 38.9 0.0 9.5e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KFM26000.1 - 1e-08 35.7 0.1 3.1e-08 34.2 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM26000.1 - 2.2e-08 34.1 0.0 3.5e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFM26000.1 - 1.7e-05 24.4 0.0 3.4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 KFM26000.1 - 7.5e-05 22.6 0.0 0.00017 21.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 KFM26000.1 - 0.00013 21.9 0.0 0.00022 21.2 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase CMAS PF02353.20 KFM26000.1 - 0.00021 20.7 0.3 0.00097 18.5 0.1 1.8 1 1 1 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 KFM26000.1 - 0.00033 20.6 0.0 0.00058 19.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KFM26000.1 - 0.00057 18.9 0.0 0.00092 18.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) TRF PF08558.10 KFM26000.1 - 0.0069 16.0 0.0 3.2 7.3 0.0 2.2 1 1 1 2 2 2 2 Telomere repeat binding factor (TRF) Methyltransf_24 PF13578.6 KFM26000.1 - 0.02 15.9 0.0 0.059 14.4 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 KFM26000.1 - 0.022 14.5 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein TehB PF03848.14 KFM26000.1 - 0.03 13.7 0.0 0.045 13.2 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB GidB PF02527.15 KFM26000.1 - 0.041 13.2 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Cons_hypoth95 PF03602.15 KFM26000.1 - 0.06 13.0 0.0 0.098 12.3 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PCMT PF01135.19 KFM26000.1 - 0.063 13.0 0.1 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 KFM26000.1 - 0.073 13.8 0.0 0.2 12.4 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 KFM26000.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_32 PF13679.6 KFM26000.1 - 0.17 11.9 0.0 0.26 11.2 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain SNARE PF05739.19 KFM26001.1 - 2.3e-07 30.7 1.9 4e-07 29.9 1.9 1.4 1 0 0 1 1 1 1 SNARE domain Tropomyosin PF00261.20 KFM26001.1 - 0.04 13.3 2.9 0.094 12.1 2.9 1.6 1 0 0 1 1 1 0 Tropomyosin DUF1542 PF07564.11 KFM26001.1 - 0.091 12.9 0.3 0.22 11.7 0.0 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) Fusion_gly PF00523.18 KFM26001.1 - 0.21 9.8 0.2 0.29 9.4 0.2 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 DUF3040 PF11239.8 KFM26001.1 - 0.4 11.0 3.6 0.53 10.6 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Tropomyosin_1 PF12718.7 KFM26001.1 - 0.75 9.9 7.5 0.099 12.8 1.4 2.4 3 0 0 3 3 3 0 Tropomyosin like UPF0258 PF06789.12 KFM26001.1 - 0.91 9.7 2.1 1.6 8.8 2.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) CS PF04969.16 KFM26002.1 - 5.9e-13 49.6 0.0 8.7e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 CS domain SecY PF00344.20 KFM26004.1 - 3.4e-79 266.3 3.4 4.2e-79 266.0 3.4 1.1 1 0 0 1 1 1 1 SecY translocase SNF2_N PF00176.23 KFM26005.1 - 5.4e-25 87.8 0.0 6.9e-25 87.5 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 KFM26005.1 - 0.028 14.4 0.0 0.056 13.5 0.0 1.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit N-glycanase_C PF09113.10 KFM26005.1 - 0.23 11.2 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 Peptide-N-glycosidase F, C terminal Helicase_C PF00271.31 KFM26006.1 - 4.9e-17 62.3 0.0 8.5e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KFM26006.1 - 5.1e-17 61.6 0.0 6.7e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HDA2-3 PF11496.8 KFM26006.1 - 0.002 17.4 0.0 0.59 9.2 0.0 2.3 2 0 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 KFM26006.1 - 0.071 12.3 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Aldedh PF00171.22 KFM26007.1 - 4.4e-178 592.5 0.0 4.9e-178 592.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1350 PF07082.11 KFM26007.1 - 0.00074 18.9 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1350) Aconitase PF00330.20 KFM26008.1 - 5e-83 279.6 0.7 2.4e-57 195.0 0.0 2.1 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) SIR2 PF02146.17 KFM26008.1 - 4.6e-27 95.1 0.0 4.5e-19 69.1 0.0 2.6 1 1 1 2 2 2 2 Sir2 family WD40 PF00400.32 KFM26009.1 - 1.3e-21 76.5 0.1 1.4e-05 25.7 0.0 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat DEAD PF00270.29 KFM26009.1 - 8.9e-11 41.9 0.0 1.5e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ANAPC4_WD40 PF12894.7 KFM26009.1 - 0.0064 16.8 0.0 2.2 8.6 0.0 2.9 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFM26009.1 - 0.016 14.6 0.0 2.6 7.3 0.0 2.2 1 1 1 2 2 2 0 WD40-like domain Ge1_WD40 PF16529.5 KFM26009.1 - 0.028 13.4 0.1 2.2 7.2 0.0 2.6 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ResIII PF04851.15 KFM26009.1 - 0.042 13.9 0.0 0.062 13.3 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NAD_Gly3P_dh_N PF01210.23 KFM26010.1 - 2.1e-47 161.0 0.1 3.2e-47 160.4 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 KFM26010.1 - 2e-46 157.8 0.6 3.8e-46 156.9 0.6 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus ApbA PF02558.16 KFM26010.1 - 8.5e-06 25.5 0.0 1.5e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 KFM26010.1 - 8.7e-06 26.0 0.1 2.4e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KFM26010.1 - 1.1e-05 25.9 0.0 5.3e-05 23.7 0.0 2.3 2 0 0 2 2 1 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.14 KFM26010.1 - 0.00019 21.1 0.0 0.00047 19.8 0.0 1.8 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 KFM26010.1 - 0.00043 19.6 0.1 0.0019 17.6 0.0 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KFM26010.1 - 0.0011 18.9 1.1 0.0019 18.1 0.3 1.9 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KFM26010.1 - 0.0048 17.4 0.4 0.16 12.5 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFM26010.1 - 0.0064 15.8 0.6 0.02 14.2 0.0 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KFM26010.1 - 0.016 14.3 0.4 0.025 13.7 0.4 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Rossmann-like PF10727.9 KFM26010.1 - 0.036 13.9 0.1 0.19 11.6 0.1 2.2 1 1 0 1 1 1 0 Rossmann-like domain FAD_oxidored PF12831.7 KFM26010.1 - 0.11 11.8 0.2 0.16 11.3 0.2 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase RNase_T PF00929.24 KFM26011.1 - 3.3e-09 37.5 0.0 4.3e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Exonuclease Glyco_hydro_39 PF01229.17 KFM26011.1 - 0.034 12.7 0.0 0.04 12.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 39 mCpol PF18182.1 KFM26012.1 - 0.08 13.3 0.0 0.16 12.3 0.0 1.6 1 1 0 1 1 1 0 minimal CRISPR polymerase domain BUD22 PF09073.10 KFM26013.1 - 1.5e-12 47.6 38.9 7.9e-06 25.5 8.0 4.0 2 1 1 3 3 3 2 BUD22 30K_MP_C_Ter PF11330.8 KFM26013.1 - 0.015 14.6 0.1 0.024 14.0 0.1 1.2 1 0 0 1 1 1 0 C-Terminal of 30K viral movement proteins ABC_membrane_2 PF06472.15 KFM26014.1 - 2.1e-114 381.5 0.0 3.6e-58 197.1 0.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KFM26014.1 - 1.3e-30 106.7 0.0 1e-14 55.2 0.0 3.4 2 1 1 3 3 3 3 ABC transporter AAA_21 PF13304.6 KFM26014.1 - 5.9e-09 36.2 0.1 0.0015 18.4 0.0 2.8 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KFM26014.1 - 3.3e-06 27.6 3.9 0.06 13.7 0.0 3.9 4 0 0 4 4 4 2 AAA ATPase domain AAA_29 PF13555.6 KFM26014.1 - 3.5e-06 26.7 0.0 0.019 14.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KFM26014.1 - 1.5e-05 25.6 0.0 0.24 11.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KFM26014.1 - 0.00036 20.1 0.0 0.4 10.2 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_22 PF13401.6 KFM26014.1 - 0.0035 17.6 0.0 2.1 8.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KFM26014.1 - 0.0044 16.5 0.0 3.5 7.0 0.0 3.3 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain Mg_chelatase PF01078.21 KFM26014.1 - 0.0068 15.8 0.2 0.65 9.3 0.2 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_27 PF13514.6 KFM26014.1 - 0.018 14.6 0.0 3.6 7.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KFM26014.1 - 0.04 14.5 0.0 2.5 8.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KFM26014.1 - 0.047 14.1 0.3 2.1 8.8 0.1 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KFM26014.1 - 0.051 13.5 0.1 2.4 8.0 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 KFM26014.1 - 0.054 13.4 0.0 13 5.6 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 KFM26014.1 - 0.11 12.2 0.0 15 5.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain TraG-D_C PF12696.7 KFM26014.1 - 0.11 12.5 0.0 0.59 10.1 0.0 2.0 2 0 0 2 2 2 0 TraM recognition site of TraD and TraG IstB_IS21 PF01695.17 KFM26014.1 - 0.13 12.0 0.0 22 4.7 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_25 PF13481.6 KFM26014.1 - 0.13 11.8 0.6 39 3.7 0.0 3.4 3 0 0 3 3 3 0 AAA domain Sigma54_activ_2 PF14532.6 KFM26014.1 - 0.15 12.2 0.0 11 6.1 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain NACHT PF05729.12 KFM26014.1 - 0.16 11.9 0.0 4.7 7.1 0.0 2.5 2 0 0 2 2 2 0 NACHT domain Rad17 PF03215.15 KFM26014.1 - 0.22 11.4 0.0 9.9 6.0 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain Terminase_GpA PF05876.12 KFM26015.1 - 5.3e-06 25.3 0.1 0.057 12.0 0.0 2.1 2 0 0 2 2 2 2 Phage terminase large subunit (GpA) TerY_C PF15616.6 KFM26015.1 - 0.00015 21.9 4.9 0.13 12.3 0.7 2.3 2 0 0 2 2 2 2 TerY-C metal binding domain Zn-ribbon_8 PF09723.10 KFM26015.1 - 0.001 19.2 1.2 15 5.8 0.0 4.3 4 0 0 4 4 4 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 KFM26015.1 - 0.0032 16.9 10.4 3.4 7.3 0.3 4.3 4 0 0 4 4 4 2 TFIIB zinc-binding DUF3920 PF13058.6 KFM26015.1 - 0.0079 16.4 0.1 4.6 7.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3920) PUA_3 PF17785.1 KFM26015.1 - 0.011 15.5 0.0 12 5.8 0.0 3.1 4 0 0 4 4 4 0 PUA-like domain zinc_ribbon_12 PF11331.8 KFM26015.1 - 0.029 14.2 0.1 13 5.7 0.0 2.7 2 0 0 2 2 2 0 Probable zinc-ribbon domain zf-FPG_IleRS PF06827.14 KFM26015.1 - 0.054 13.4 4.1 5.1 7.1 0.3 2.7 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zf_Rg PF17915.1 KFM26015.1 - 0.069 12.6 0.5 17 4.9 0.1 2.6 2 0 0 2 2 2 0 Reverse gyrase zinc finger DUF4731 PF15875.5 KFM26015.1 - 0.07 13.3 0.0 16 5.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4731) DUF2752 PF10825.8 KFM26015.1 - 0.079 13.0 4.6 6.1 7.0 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2752) DUF1235 PF06822.12 KFM26015.1 - 0.084 12.2 0.0 13 5.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1235) SHOCT PF09851.9 KFM26015.1 - 0.11 12.3 8.8 58 3.6 0.0 4.4 4 0 0 4 4 4 0 Short C-terminal domain Ribosomal_S27e PF01667.17 KFM26015.1 - 0.12 12.1 11.8 1.4 8.7 0.8 4.2 4 0 0 4 4 4 0 Ribosomal protein S27 DpnI PF06044.12 KFM26015.1 - 0.14 11.8 3.8 6.9 6.3 0.1 2.2 2 0 0 2 2 2 0 Dam-replacing family zf-C2H2_11 PF16622.5 KFM26015.1 - 0.15 11.9 1.5 20 5.0 0.1 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type Lar_restr_allev PF14354.6 KFM26015.1 - 0.22 11.9 7.2 4.9 7.6 0.5 2.7 2 0 0 2 2 2 0 Restriction alleviation protein Lar FemAB_like PF04339.12 KFM26015.1 - 0.23 10.6 0.0 21 4.1 0.0 2.1 2 0 0 2 2 2 0 Peptidogalycan biosysnthesis/recognition DZR PF12773.7 KFM26015.1 - 0.31 11.1 8.6 5.2 7.2 0.7 3.0 2 1 0 2 2 2 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.7 KFM26015.1 - 0.39 10.7 8.8 6.3 6.9 1.2 3.0 2 2 0 2 2 2 0 Transposase zinc-ribbon domain zf-ISL3 PF14690.6 KFM26015.1 - 0.45 11.2 7.4 12 6.6 0.1 3.6 4 0 0 4 4 4 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 TFIIS_C PF01096.18 KFM26015.1 - 0.82 9.6 12.0 7 6.6 0.1 4.2 4 0 0 4 4 4 0 Transcription factor S-II (TFIIS) OrfB_Zn_ribbon PF07282.11 KFM26015.1 - 0.83 9.6 6.1 12 5.9 0.5 2.6 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-tcix PF14952.6 KFM26015.1 - 2 8.1 5.7 22 4.8 0.5 2.7 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding zf-ribbon_3 PF13248.6 KFM26015.1 - 3.1 7.3 10.6 7.5 6.1 0.3 3.7 4 0 0 4 4 4 0 zinc-ribbon domain Elf1 PF05129.13 KFM26015.1 - 5 7.2 10.1 13 5.9 2.0 2.9 2 2 0 2 2 2 0 Transcription elongation factor Elf1 like zinc_ribbon_15 PF17032.5 KFM26015.1 - 9.7 7.0 10.2 39 5.1 1.0 3.3 2 2 1 3 3 3 0 zinc-ribbon family E1-E2_ATPase PF00122.20 KFM26016.1 - 3.7e-26 91.8 0.1 7.6e-26 90.7 0.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase HMA PF00403.26 KFM26016.1 - 9.7e-09 35.6 0.0 2.2e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase PF00702.26 KFM26016.1 - 5.6e-05 23.5 0.1 0.00011 22.5 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMP1 PF05348.11 KFM26017.1 - 2.2e-20 73.0 0.0 2.5e-20 72.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 ubiquitin PF00240.23 KFM26019.1 - 1.8e-14 53.3 0.0 2.7e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 KFM26019.1 - 4.5e-10 39.2 0.2 4.5e-10 39.2 0.2 2.4 3 0 0 3 3 3 1 UBA/TS-N domain STI1 PF17830.1 KFM26019.1 - 4.4e-09 36.1 31.1 3.8e-05 23.5 1.9 5.0 2 2 1 4 4 4 3 STI1 domain Rad60-SLD PF11976.8 KFM26019.1 - 7.6e-07 28.9 0.0 1.3e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KFM26019.1 - 0.0028 18.2 0.0 0.0056 17.2 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KFM26019.1 - 0.0053 16.9 0.0 0.014 15.5 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 KFM26019.1 - 0.057 13.5 0.0 12 6.1 0.0 2.3 1 1 1 2 2 2 0 Ubiquitin-like domain HOIP-UBA PF16678.5 KFM26019.1 - 0.063 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 HOIP UBA domain pair CUE PF02845.16 KFM26019.1 - 0.27 11.0 1.1 18 5.2 0.0 3.3 3 0 0 3 3 3 0 CUE domain GerD PF17898.1 KFM26019.1 - 0.42 10.6 9.6 2.9 7.9 1.8 3.1 2 2 1 3 3 3 0 Spore germination GerD central core domain LPD22 PF18834.1 KFM26019.1 - 0.46 10.7 10.5 13 6.1 0.6 3.8 2 2 2 4 4 4 0 Large polyvalent protein associated domain 22 Ribosomal_L24e PF01246.20 KFM26020.1 - 4.4e-27 94.1 0.2 4.4e-27 94.1 0.2 2.1 2 1 0 2 2 2 1 Ribosomal protein L24e M-inducer_phosp PF06617.13 KFM26020.1 - 0.3 10.3 8.5 0.17 11.1 5.9 1.8 1 1 1 2 2 2 0 M-phase inducer phosphatase Spore_coat_CotO PF14153.6 KFM26020.1 - 1.6 8.6 9.5 2.1 8.3 9.5 1.1 1 0 0 1 1 1 0 Spore coat protein CotO ketoacyl-synt PF00109.26 KFM26022.1 - 2.4e-51 174.7 1.4 4.4e-51 173.9 1.4 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KFM26022.1 - 2.3e-34 117.9 0.2 4.8e-34 116.9 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 KFM26022.1 - 0.028 13.8 0.5 0.06 12.7 0.5 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain ACP_syn_III PF08545.10 KFM26022.1 - 0.24 11.3 1.8 13 5.8 0.0 2.7 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III WD40 PF00400.32 KFM26023.1 - 1.8e-05 25.4 1.4 2 9.4 0.0 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat DSS1_SEM1 PF05160.13 KFM26024.1 - 0.027 14.5 0.1 0.027 14.5 0.1 2.0 2 0 0 2 2 2 0 DSS1/SEM1 family DUF4847 PF16139.5 KFM26024.1 - 0.032 14.1 0.0 0.04 13.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4847) mTERF PF02536.14 KFM26025.1 - 2.5e-13 49.6 0.0 7.1e-09 35.0 0.0 2.1 1 1 1 2 2 2 2 mTERF AAA_11 PF13086.6 KFM26026.1 - 6.6e-53 180.2 0.0 5.8e-52 177.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.6 KFM26026.1 - 2.6e-49 167.5 0.0 4.4e-49 166.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFM26026.1 - 7.6e-07 29.0 7.8 0.0037 17.0 0.4 3.2 4 0 0 4 4 4 2 AAA domain Viral_helicase1 PF01443.18 KFM26026.1 - 3.3e-06 27.0 0.1 0.025 14.3 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 KFM26026.1 - 9.8e-06 26.0 0.6 0.00033 21.0 0.6 2.7 1 1 0 1 1 1 1 AAA domain MCPsignal PF00015.21 KFM26026.1 - 0.0002 21.2 2.6 0.00036 20.4 2.6 1.3 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain UvrD_C_2 PF13538.6 KFM26026.1 - 0.00065 19.5 0.4 0.0017 18.1 0.4 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 KFM26026.1 - 0.0013 18.3 0.0 0.005 16.4 0.0 1.8 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain WEMBL PF05701.11 KFM26026.1 - 0.017 13.8 8.4 0.025 13.3 8.4 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light AAA_25 PF13481.6 KFM26026.1 - 0.025 14.2 0.2 0.079 12.5 0.2 1.9 1 0 0 1 1 1 0 AAA domain Cluap1 PF10234.9 KFM26026.1 - 0.028 13.8 5.4 0.042 13.2 5.4 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 GCIP PF13324.6 KFM26026.1 - 0.032 13.8 0.2 0.05 13.2 0.2 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting AAA_24 PF13479.6 KFM26026.1 - 0.059 13.1 0.1 0.35 10.6 0.1 2.0 1 1 0 1 1 1 0 AAA domain Golgin_A5 PF09787.9 KFM26026.1 - 0.23 10.9 9.3 0.36 10.3 9.3 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF4407 PF14362.6 KFM26026.1 - 0.23 10.8 5.7 0.38 10.1 5.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA PF00004.29 KFM26026.1 - 0.33 11.4 1.7 0.63 10.5 0.6 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Spc7 PF08317.11 KFM26026.1 - 1 8.2 12.9 1.5 7.6 12.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein TilS PF09179.11 KFM26026.1 - 1.2 9.6 0.0 1.2 9.6 0.0 3.7 4 0 0 4 4 3 0 TilS substrate binding domain V_ATPase_I PF01496.19 KFM26026.1 - 2.1 6.2 5.6 2.9 5.7 5.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-F_leu_zip PF10473.9 KFM26026.1 - 2.3 8.3 14.3 4.5 7.3 14.3 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_16 PF13191.6 KFM26026.1 - 2.3 8.6 9.4 0.14 12.6 1.4 2.7 1 1 1 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 KFM26026.1 - 3.6 8.0 8.4 32 4.9 8.4 2.1 1 1 0 1 1 1 0 AAA domain FUSC PF04632.12 KFM26028.1 - 0.88 8.0 8.0 5.4 5.4 0.2 2.3 2 0 0 2 2 2 0 Fusaric acid resistance protein family Arginosuc_synth PF00764.19 KFM26030.1 - 6.7e-156 519.4 0.0 7.9e-156 519.2 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 KFM26030.1 - 0.00048 19.7 0.0 0.00076 19.0 0.0 1.2 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 KFM26030.1 - 0.0031 17.2 0.0 0.0047 16.6 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase MA3 PF02847.17 KFM26033.1 - 6.1e-25 87.4 0.6 1.4e-24 86.2 0.6 1.7 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 KFM26033.1 - 3.8e-14 52.8 0.1 1.6e-13 50.8 0.0 2.0 3 0 0 3 3 3 1 MIF4G domain Herpes_U30 PF04523.13 KFM26033.1 - 0.093 10.6 0.1 0.13 10.1 0.1 1.1 1 0 0 1 1 1 0 Herpes virus tegument protein U30 Herpes_capsid PF06112.11 KFM26033.1 - 0.15 12.2 31.7 0.33 11.0 31.7 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein SPX PF03105.19 KFM26033.1 - 0.23 11.3 14.2 0.052 13.5 10.7 1.7 2 0 0 2 2 2 0 SPX domain FAM199X PF15814.5 KFM26033.1 - 0.29 10.2 17.0 0.44 9.5 17.0 1.2 1 0 0 1 1 1 0 Protein family FAM199X SUZ PF12752.7 KFM26033.1 - 2 9.2 0.0 2 9.2 0.0 4.1 3 1 0 3 3 3 0 SUZ domain Sec3_C PF09763.9 KFM26033.1 - 3.2 6.0 4.6 5.9 5.1 4.4 1.6 1 1 0 1 1 1 0 Exocyst complex component Sec3 SSP160 PF06933.11 KFM26033.1 - 3.3 5.8 27.8 5.4 5.1 27.3 1.5 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 FAM176 PF14851.6 KFM26033.1 - 3.8 7.2 8.9 2.2 7.9 1.0 3.0 3 0 0 3 3 3 0 FAM176 family Hexapep PF00132.24 KFM26034.1 - 1.3e-13 50.0 12.6 1.7e-05 24.4 0.3 4.1 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KFM26034.1 - 0.00034 20.3 11.1 0.00078 19.1 1.3 4.0 3 1 1 4 4 4 1 Hexapeptide repeat of succinyl-transferase Nucleoporin_FG2 PF15967.5 KFM26034.1 - 0.017 13.7 1.4 0.03 12.9 1.4 1.3 1 0 0 1 1 1 0 Nucleoporin FG repeated region Adap_comp_sub PF00928.21 KFM26035.1 - 5.8e-78 261.9 0.0 7e-78 261.6 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KFM26035.1 - 1.2e-05 25.3 0.0 2.4e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 KFM26035.1 - 0.0023 17.4 0.2 0.0042 16.6 0.2 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain PRP3 PF08572.10 KFM26036.1 - 1.8e-55 188.1 15.6 3.3e-53 180.7 4.5 3.1 2 1 1 3 3 3 2 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 KFM26036.1 - 2.4e-19 69.9 0.2 1.4e-11 44.6 0.0 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF1115) Pirin PF02678.16 KFM26037.1 - 5e-35 119.7 0.3 1e-34 118.7 0.2 1.6 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.13 KFM26037.1 - 1.6e-27 95.9 0.0 3.1e-27 95.0 0.0 1.5 1 0 0 1 1 1 1 Pirin C-terminal cupin domain GTP_EFTU PF00009.27 KFM26039.1 - 6e-54 182.6 0.0 8.2e-54 182.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KFM26039.1 - 2.7e-10 40.2 0.0 5e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 KFM26039.1 - 1.4e-08 34.7 0.0 2.9e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KFM26039.1 - 0.0006 20.2 0.0 0.0033 17.8 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFM26039.1 - 0.073 13.2 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase EFG_IV PF03764.18 KFM26039.1 - 0.11 12.3 0.0 0.36 10.6 0.0 1.8 1 0 0 1 1 1 0 Elongation factor G, domain IV WD40 PF00400.32 KFM26040.1 - 3.1e-07 31.0 0.6 0.026 15.4 0.1 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM26040.1 - 2.4e-05 24.5 0.0 0.011 16.0 0.0 4.0 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain SVIP PF15811.5 KFM26040.1 - 0.23 11.9 4.4 0.56 10.7 4.4 1.6 1 0 0 1 1 1 0 Small VCP/p97-interacting protein TMEM65 PF10507.9 KFM26041.1 - 1.1e-36 125.1 1.0 1.6e-36 124.6 1.0 1.3 1 0 0 1 1 1 1 Transmembrane protein 65 UPF0184 PF03670.13 KFM26042.1 - 0.0011 19.3 0.2 0.0023 18.3 0.2 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0184) CLZ PF16526.5 KFM26042.1 - 0.069 13.5 1.8 4.2 7.8 0.4 2.1 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FUSC PF04632.12 KFM26042.1 - 0.098 11.2 0.3 0.12 10.9 0.3 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tho1_MOS11_C PF18592.1 KFM26043.1 - 1.8e-11 43.7 10.5 6.5e-05 22.7 2.4 4.3 2 1 2 4 4 4 4 Tho1/MOS11 C-terminal domain SAP PF02037.27 KFM26043.1 - 1.6e-10 40.4 1.2 1.6e-10 40.4 1.2 3.0 3 0 0 3 3 3 1 SAP domain DNA_pol_delta_4 PF04081.13 KFM26043.1 - 0.099 13.0 0.4 0.099 13.0 0.4 2.4 2 1 0 3 3 3 0 DNA polymerase delta, subunit 4 TMEM252 PF15664.5 KFM26043.1 - 0.85 9.3 4.6 0.24 11.1 0.2 2.1 1 1 0 2 2 2 0 Transmembrane protein 252 family EAP30 PF04157.16 KFM26044.1 - 8.5e-38 130.0 0.0 1.1e-37 129.6 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family UBA PF00627.31 KFM26044.1 - 1.6e-05 24.7 0.1 4e-05 23.4 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain PfkB PF00294.24 KFM26047.1 - 3.9e-22 78.9 5.4 8.8e-13 48.2 6.5 2.4 2 1 0 2 2 2 2 pfkB family carbohydrate kinase DUF2838 PF10998.8 KFM26048.1 - 3.3e-33 114.2 3.7 3.3e-33 114.2 3.7 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) ABC1 PF03109.16 KFM26049.1 - 5.3e-26 91.1 0.0 3.3e-14 53.1 0.0 2.3 2 0 0 2 2 2 2 ABC1 family APH PF01636.23 KFM26049.1 - 0.35 10.8 9.8 0.44 10.4 6.7 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family PP2C PF00481.21 KFM26050.1 - 9.8e-27 94.2 0.0 5.1e-26 91.9 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KFM26050.1 - 0.00095 19.1 0.4 0.0037 17.2 0.1 2.3 2 1 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KFM26050.1 - 0.0033 17.1 0.2 0.0033 17.1 0.2 2.1 2 1 0 2 2 2 1 Protein phosphatase 2C BBP1_C PF15272.6 KFM26051.1 - 0.037 13.9 2.0 0.053 13.3 2.0 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Tup_N PF08581.10 KFM26051.1 - 0.13 12.6 9.4 0.33 11.3 2.8 2.3 1 1 0 2 2 2 0 Tup N-terminal PDDEXK_6 PF04720.12 KFM26051.1 - 0.55 10.1 7.2 0.83 9.6 6.9 1.4 1 1 0 1 1 1 0 PDDEXK-like family of unknown function UPF0231 PF06062.11 KFM26051.1 - 0.82 10.0 5.9 18 5.6 0.0 2.3 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0231) Filament PF00038.21 KFM26051.1 - 4.7 6.7 16.2 17 4.9 15.3 1.8 1 1 1 2 2 2 0 Intermediate filament protein DUF4407 PF14362.6 KFM26051.1 - 4.8 6.5 9.5 5.5 6.2 9.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pre-PUA PF17832.1 KFM26052.1 - 1.7e-14 54.3 0.1 1.3e-13 51.4 0.0 2.3 2 0 0 2 2 2 1 Pre-PUA-like domain SUI1 PF01253.22 KFM26052.1 - 9.9e-14 51.6 0.0 2.5e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 Toluene_X PF03349.16 KFM26052.1 - 0.098 11.2 0.2 0.15 10.6 0.2 1.2 1 0 0 1 1 1 0 Outer membrane protein transport protein (OMPP1/FadL/TodX) Sec63 PF02889.16 KFM26053.1 - 2.3e-98 328.5 0.0 1.1e-76 257.4 0.0 2.7 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KFM26053.1 - 4.1e-46 157.0 0.4 4.5e-28 98.2 0.4 2.8 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 KFM26053.1 - 3.3e-24 85.8 0.0 4.4e-11 43.1 0.0 2.3 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KFM26053.1 - 1.7e-09 38.1 0.1 0.0018 18.5 0.0 3.0 2 0 0 2 2 2 2 AAA domain Helicase_C PF00271.31 KFM26053.1 - 5.4e-07 29.9 0.0 0.00021 21.6 0.0 3.3 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 KFM26053.1 - 4.4e-05 23.9 1.0 0.49 10.7 0.4 2.9 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 KFM26053.1 - 4.6e-05 22.6 0.0 0.11 11.5 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein PhoH PF02562.16 KFM26053.1 - 0.00061 19.3 0.2 0.57 9.6 0.0 2.8 3 0 0 3 3 3 2 PhoH-like protein UvrD-helicase PF00580.21 KFM26053.1 - 0.0027 17.3 0.3 2.2 7.7 0.1 2.3 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 KFM26053.1 - 0.0043 16.3 0.0 3.2 6.9 0.0 2.9 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.17 KFM26053.1 - 0.0094 15.7 0.6 1.1 8.9 0.0 3.4 5 0 0 5 5 5 1 IstB-like ATP binding protein AAA_7 PF12775.7 KFM26053.1 - 0.045 13.2 0.0 8.5 5.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_11 PF13086.6 KFM26053.1 - 0.094 12.5 0.0 7.2 6.3 0.0 2.8 2 1 1 3 3 3 0 AAA domain EccE PF11203.8 KFM26053.1 - 6.4 7.2 6.4 33 4.9 0.2 3.9 4 0 0 4 4 4 0 Putative type VII ESX secretion system translocon, EccE adh_short PF00106.25 KFM26054.1 - 8.9e-28 97.1 0.0 1.3e-27 96.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM26054.1 - 5.9e-18 65.3 0.0 7.8e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM26054.1 - 5.2e-08 33.0 0.0 8.1e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KFM26054.1 - 0.013 15.4 0.0 0.021 14.7 0.0 1.4 1 1 0 1 1 1 0 NAD(P)H-binding Epimerase PF01370.21 KFM26054.1 - 0.017 14.6 0.0 0.034 13.6 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KFM26054.1 - 0.086 12.2 0.0 0.19 11.1 0.0 1.5 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.18 KFM26054.1 - 0.089 12.7 0.0 0.71 9.7 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.8 KFM26054.1 - 0.13 12.0 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Radical_SAM PF04055.21 KFM26055.1 - 5e-19 69.3 0.0 7.8e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Pkinase PF00069.25 KFM26057.1 - 7.7e-19 68.1 0.0 8.2e-19 68.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM26057.1 - 2.2e-08 33.7 0.0 2.4e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM26057.1 - 1.4e-05 24.6 0.0 1.4e-05 24.5 0.0 1.0 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFM26057.1 - 0.00013 20.9 0.1 0.00014 20.8 0.1 1.0 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFM26057.1 - 0.00085 19.3 0.0 0.001 19.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KFM26057.1 - 0.0023 17.0 0.0 0.0027 16.8 0.0 1.1 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 KFM26057.1 - 0.039 13.3 0.0 0.044 13.1 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KFM26057.1 - 0.19 11.3 0.0 0.22 11.1 0.0 1.1 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Glutaredoxin PF00462.24 KFM26058.1 - 5.4e-12 45.7 2.1 9.3e-12 45.0 2.1 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 KFM26058.1 - 8.6e-12 45.3 0.0 1.9e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 KFM26058.1 - 1.6e-07 32.0 0.0 6.7e-07 30.0 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_N_2 PF13409.6 KFM26058.1 - 1.5e-05 25.2 0.0 2.4e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KFM26058.1 - 0.0024 18.2 0.0 0.0041 17.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFM26058.1 - 0.026 14.6 0.0 0.045 13.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF836 PF05768.14 KFM26058.1 - 0.13 12.7 0.5 0.31 11.5 0.1 1.7 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) Pkinase PF00069.25 KFM26059.1 - 3.2e-61 207.0 0.0 4e-61 206.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM26059.1 - 2e-28 99.4 0.0 2.7e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.29 KFM26059.1 - 9.1e-07 28.9 0.0 2.3e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Kinase-like PF14531.6 KFM26059.1 - 0.00026 20.4 0.0 0.00075 18.9 0.0 1.6 1 1 0 1 1 1 1 Kinase-like FTA2 PF13095.6 KFM26059.1 - 0.027 14.1 0.0 0.55 9.8 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 WD40 PF00400.32 KFM26060.1 - 1.5e-26 92.1 4.0 1.4e-06 28.9 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat Sof1 PF04158.14 KFM26060.1 - 5.6e-24 84.2 5.7 9.7e-24 83.5 5.7 1.4 1 0 0 1 1 1 1 Sof1-like domain ANAPC4_WD40 PF12894.7 KFM26060.1 - 2e-05 24.8 0.0 8.8 6.7 0.0 4.6 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Amino_oxidase PF01593.24 KFM26062.1 - 1.3e-74 252.2 0.6 1.6e-74 251.9 0.6 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFM26062.1 - 1.6e-12 47.4 3.2 2e-11 43.9 2.0 3.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain SWIRM PF04433.17 KFM26062.1 - 2.3e-08 34.3 0.0 4e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 SWIRM domain Pyr_redox_2 PF07992.14 KFM26062.1 - 6.1e-06 25.7 1.9 9.3e-06 25.1 1.9 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFM26062.1 - 6e-05 21.9 0.3 8.9e-05 21.4 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 KFM26062.1 - 0.00018 21.2 6.3 0.0015 18.2 6.3 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFM26062.1 - 0.00025 20.3 2.7 0.00025 20.3 2.7 2.3 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KFM26062.1 - 0.00034 19.9 0.1 0.00058 19.2 0.1 1.2 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 KFM26062.1 - 0.00046 19.5 0.4 0.001 18.4 0.4 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 KFM26062.1 - 0.0014 18.0 0.8 0.0025 17.1 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KFM26062.1 - 0.0022 17.4 1.1 0.0039 16.6 1.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KFM26062.1 - 0.005 17.4 0.3 0.011 16.3 0.3 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFM26062.1 - 0.0052 16.1 0.2 0.012 14.9 0.1 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KFM26062.1 - 0.012 14.7 2.0 0.018 14.1 2.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KFM26062.1 - 0.023 13.7 0.2 0.052 12.6 0.2 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein Glu_dehyd_C PF16912.5 KFM26062.1 - 0.15 11.5 0.1 0.27 10.7 0.1 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus AF-4 PF05110.13 KFM26062.1 - 5.9 4.8 19.1 9 4.2 19.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SAND PF01342.21 KFM26063.1 - 2.3e-05 24.0 0.0 5.6e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 SAND domain DER1 PF04511.15 KFM26064.1 - 1.8e-29 103.1 0.6 2.1e-29 102.8 0.6 1.0 1 0 0 1 1 1 1 Der1-like family Glutaredoxin PF00462.24 KFM26065.1 - 3.9e-13 49.4 0.0 6.3e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin DUF410 PF04190.13 KFM26066.1 - 4.5e-09 36.5 0.0 2.7e-08 33.9 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF410) CorA PF01544.18 KFM26067.1 - 0.0007 19.0 0.2 0.0017 17.7 0.2 1.6 1 1 1 2 2 2 2 CorA-like Mg2+ transporter protein ECH_1 PF00378.20 KFM26068.1 - 6.2e-41 140.4 0.0 9.7e-41 139.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFM26068.1 - 1.4e-22 80.6 0.2 9.9e-22 77.9 0.2 1.8 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase Methyltransf_16 PF10294.9 KFM26070.1 - 5.5e-26 91.4 0.0 8.9e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase TPR_16 PF13432.6 KFM26070.1 - 1.1e-05 26.0 7.5 6.2e-05 23.6 1.6 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFM26070.1 - 1.8e-05 25.1 4.6 0.068 13.7 0.3 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFM26070.1 - 4.7e-05 23.9 13.1 0.00063 20.3 0.1 5.0 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFM26070.1 - 0.0002 21.2 0.4 0.93 9.8 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFM26070.1 - 0.0049 17.0 1.1 0.0049 17.0 1.1 3.8 3 2 1 4 4 4 1 Tetratricopeptide repeat Methyltransf_25 PF13649.6 KFM26070.1 - 0.031 15.0 0.2 0.12 13.1 0.1 2.1 2 0 0 2 2 2 0 Methyltransferase domain TPR_12 PF13424.6 KFM26070.1 - 0.034 14.4 3.4 1.4 9.3 0.3 3.2 1 1 1 2 2 2 0 Tetratricopeptide repeat MTS PF05175.14 KFM26070.1 - 0.039 13.5 0.5 0.098 12.2 0.1 1.7 2 0 0 2 2 2 0 Methyltransferase small domain TPR_17 PF13431.6 KFM26070.1 - 0.047 14.1 0.1 13 6.4 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat LigT_PEase PF02834.16 KFM26070.1 - 0.053 13.7 0.0 8 6.7 0.0 2.6 2 0 0 2 2 2 0 LigT like Phosphoesterase N_formyltrans_C PF18216.1 KFM26070.1 - 0.12 12.1 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 N-formyltransferase dimerization C-terminal domain PsaL PF02605.15 KFM26072.1 - 1e-53 181.0 0.2 1.2e-53 180.8 0.2 1.1 1 0 0 1 1 1 1 Photosystem I reaction centre subunit XI DSPc PF00782.20 KFM26073.1 - 3.2e-10 39.9 0.0 9.4e-10 38.4 0.0 1.7 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KFM26073.1 - 0.081 13.2 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 Rit1 DUSP-like domain TPR_6 PF13174.6 KFM26075.1 - 0.00033 21.1 0.8 1.6 9.6 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFM26075.1 - 0.00047 20.1 1.0 0.017 15.2 0.2 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFM26075.1 - 0.0019 18.8 1.2 0.0031 18.1 0.1 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFM26075.1 - 0.0034 18.1 2.3 1.3 10.0 0.1 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFM26075.1 - 0.032 14.1 0.4 0.3 11.0 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Acetyltransf_1 PF00583.25 KFM26076.1 - 5.4e-10 39.5 0.0 6.3e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFM26076.1 - 1e-08 35.2 0.1 1.3e-08 34.8 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFM26076.1 - 7.5e-08 32.7 0.0 1e-07 32.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFM26076.1 - 1e-06 28.6 0.1 1.5e-06 28.0 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 KFM26076.1 - 0.00023 21.3 0.0 0.00029 21.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KFM26076.1 - 0.027 14.5 0.0 0.034 14.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 KFM26076.1 - 0.052 13.3 0.0 0.072 12.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_CG PF14542.6 KFM26076.1 - 0.093 12.9 0.1 0.17 12.1 0.1 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase E3_binding PF02817.17 KFM26076.1 - 0.11 12.9 0.1 0.25 11.7 0.1 1.6 1 0 0 1 1 1 0 e3 binding domain UFC1 PF08694.11 KFM26079.1 - 2.3e-82 274.2 0.4 2.6e-82 274.0 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 UQ_con PF00179.26 KFM26079.1 - 0.00023 20.8 0.3 0.0009 18.9 0.3 1.9 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFM26079.1 - 0.0041 17.4 0.4 0.0068 16.7 0.4 1.5 1 1 0 1 1 1 1 RWD domain CDT1 PF08839.11 KFM26080.1 - 6.1e-07 29.9 0.0 8.4e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 DNA replication factor CDT1 like PTS_2-RNA PF01885.16 KFM26080.1 - 0.062 13.4 0.0 0.074 13.1 0.0 1.1 1 0 0 1 1 1 0 RNA 2'-phosphotransferase, Tpt1 / KptA family UCR_14kD PF02271.16 KFM26082.1 - 3.5e-27 94.3 0.6 4.1e-27 94.1 0.6 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit UPRTase PF14681.6 KFM26083.1 - 1.8e-67 226.8 0.0 3.1e-67 226.0 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRK PF00485.18 KFM26083.1 - 5.4e-40 137.2 0.2 8.3e-40 136.6 0.2 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 KFM26083.1 - 0.0002 21.9 0.0 0.00036 21.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 KFM26083.1 - 0.013 15.3 0.3 0.57 9.9 0.0 2.2 1 1 1 2 2 2 0 Cytidylate kinase AAA_33 PF13671.6 KFM26083.1 - 0.022 14.9 0.1 0.073 13.2 0.0 2.0 2 1 0 2 2 2 0 AAA domain Pribosyltran PF00156.27 KFM26083.1 - 0.029 13.9 0.0 0.056 13.0 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosyl transferase domain AAA_17 PF13207.6 KFM26083.1 - 0.062 13.7 0.5 0.23 11.9 0.5 2.0 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KFM26083.1 - 0.081 12.2 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF1635 PF07795.11 KFM26084.1 - 0.11 12.3 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) UPRTase PF14681.6 KFM26085.1 - 2e-67 226.6 0.0 3.3e-67 226.0 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRK PF00485.18 KFM26085.1 - 2.2e-30 105.9 0.1 5.8e-30 104.5 0.1 1.6 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Pribosyltran PF00156.27 KFM26085.1 - 0.00013 21.6 0.0 0.00029 20.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain TLC PF03219.14 KFM26086.1 - 5.4e-123 411.3 3.8 6.6e-123 411.0 3.8 1.0 1 0 0 1 1 1 1 TLC ATP/ADP transporter LON_substr_bdg PF02190.16 KFM26087.1 - 2.5e-19 70.0 0.0 3.9e-19 69.4 0.0 1.3 1 1 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AMPK1_CBM PF16561.5 KFM26088.1 - 4.5e-29 100.5 0.4 6.7e-29 99.9 0.4 1.2 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 KFM26088.1 - 5e-20 71.6 2.1 1.2e-19 70.4 2.1 1.6 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain Band_7 PF01145.25 KFM26089.1 - 5e-21 75.5 3.9 9.7e-21 74.6 3.9 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 KFM26089.1 - 4.3e-06 26.0 4.0 5.7e-06 25.6 4.0 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial DUF1191 PF06697.12 KFM26089.1 - 0.00067 19.5 0.0 0.00098 18.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Peptidase_S8 PF00082.22 KFM26091.1 - 6.2e-36 124.2 13.2 9e-36 123.7 13.2 1.2 1 0 0 1 1 1 1 Subtilase family ThiF PF00899.21 KFM26093.1 - 3.4e-23 82.3 0.0 9.3e-23 80.8 0.0 1.6 1 1 0 1 1 1 1 ThiF family DUF21 PF01595.20 KFM26096.1 - 7.4e-39 133.2 1.2 7.4e-39 133.2 1.2 2.0 2 1 1 3 3 3 1 Cyclin M transmembrane N-terminal domain SNARE_assoc PF09335.11 KFM26096.1 - 1.7e-17 64.0 7.0 1.7e-17 64.0 7.0 2.6 3 0 0 3 3 3 1 SNARE associated Golgi protein CBS PF00571.28 KFM26096.1 - 0.073 13.5 0.1 8.9 6.9 0.0 2.6 2 0 0 2 2 2 0 CBS domain LexA_DNA_bind PF01726.16 KFM26097.1 - 0.033 14.0 0.0 0.055 13.3 0.0 1.3 1 0 0 1 1 1 0 LexA DNA binding domain SNF2_N PF00176.23 KFM26098.1 - 9.9e-60 202.1 0.0 1.5e-59 201.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFM26098.1 - 1.2e-15 57.8 0.0 3e-15 56.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM26098.1 - 4.5e-07 30.0 0.0 8.1e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFM26098.1 - 0.00016 21.5 0.0 0.00032 20.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 KFM26098.1 - 0.14 11.3 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 KFM26098.1 - 0.2 11.3 0.0 0.37 10.4 0.0 1.4 1 1 0 1 1 1 0 SWI2/SNF2 ATPase SurE PF01975.17 KFM26099.1 - 1.8e-49 168.2 0.0 2.4e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE ADK PF00406.22 KFM26100.1 - 0.0033 17.5 0.2 1 9.5 0.1 2.4 1 1 1 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 KFM26100.1 - 0.21 12.0 0.3 12 6.3 0.1 2.4 1 1 1 2 2 2 0 AAA domain OB_NTP_bind PF07717.16 KFM26101.1 - 4.5e-10 39.8 0.0 8.8e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KFM26101.1 - 7.6e-09 35.9 0.0 1.5e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFM26101.1 - 6e-05 22.9 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase PRP4 PF08799.11 KFM26101.1 - 0.078 12.6 0.0 0.28 10.8 0.0 2.0 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like DUF2917 PF11142.8 KFM26101.1 - 0.14 11.6 2.2 9.7 5.7 0.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2917) APG5 PF04106.12 KFM26102.1 - 4.1e-13 49.5 0.0 5.3e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 cobW PF02492.19 KFM26103.1 - 2.8e-50 170.3 0.1 3.6e-50 170.0 0.1 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KFM26103.1 - 8.1e-19 67.4 0.2 1.4e-18 66.6 0.2 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 KFM26103.1 - 2.7e-05 24.1 0.0 0.022 14.7 0.0 2.5 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KFM26103.1 - 9.1e-05 22.5 0.0 0.00022 21.3 0.0 1.7 2 0 0 2 2 1 1 50S ribosome-binding GTPase MeaB PF03308.16 KFM26103.1 - 0.0015 17.6 0.1 0.28 10.1 0.0 3.1 4 0 0 4 4 4 1 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 KFM26103.1 - 0.0029 17.2 0.1 0.037 13.6 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 KFM26103.1 - 0.0042 16.8 0.2 0.012 15.3 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KFM26103.1 - 0.006 16.8 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 KFM26103.1 - 0.012 16.1 0.0 0.02 15.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFM26103.1 - 0.013 15.9 0.1 0.032 14.6 0.1 1.9 2 1 0 2 2 1 0 AAA ATPase domain FeoB_N PF02421.18 KFM26103.1 - 0.02 14.5 0.3 0.43 10.1 0.0 2.3 2 1 0 2 2 2 0 Ferrous iron transport protein B ABC_tran PF00005.27 KFM26103.1 - 0.075 13.5 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Viral_helicase1 PF01443.18 KFM26103.1 - 0.076 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 KFM26103.1 - 0.17 12.4 0.0 1.3 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KFM26103.1 - 0.19 11.6 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 NTPase ATPase_2 PF01637.18 KFM26103.1 - 0.25 11.2 0.0 0.35 10.7 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Bystin PF05291.11 KFM26104.1 - 2.3e-126 421.0 0.0 2.9e-126 420.7 0.0 1.1 1 0 0 1 1 1 1 Bystin TetR_C_15 PF17918.1 KFM26104.1 - 5.2 7.9 7.4 0.56 11.0 1.4 2.5 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain SKIP_SNW PF02731.15 KFM26106.1 - 6.9e-59 198.1 0.0 6.9e-59 198.1 0.0 2.2 2 0 0 2 2 2 1 SKIP/SNW domain Inositol_P PF00459.25 KFM26107.1 - 1.1e-48 166.2 0.1 1.4e-48 165.8 0.1 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family Yip1 PF04893.17 KFM26108.1 - 2.4e-08 33.9 15.0 3.7e-08 33.3 15.0 1.4 1 0 0 1 1 1 1 Yip1 domain YIF1 PF03878.15 KFM26108.1 - 2.5 7.6 10.8 11 5.5 4.7 2.4 2 1 0 2 2 2 0 YIF1 Peptidase_M16 PF00675.20 KFM26109.1 - 3.5e-33 114.7 0.0 6.9e-33 113.7 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KFM26109.1 - 1.7e-20 73.8 0.0 7.4e-19 68.5 0.0 2.3 1 1 1 2 2 2 1 Peptidase M16 inactive domain DUF2076 PF09849.9 KFM26109.1 - 0.13 12.3 0.1 0.24 11.4 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Extensin_2 PF04554.13 KFM26110.1 - 0.061 13.4 13.4 0.075 13.1 13.4 1.2 1 0 0 1 1 1 0 Extensin-like region PH PF00169.29 KFM26111.1 - 3.6e-09 37.1 0.0 5.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFM26111.1 - 0.00016 22.0 0.1 0.077 13.4 0.0 2.1 1 1 1 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 KFM26111.1 - 0.0002 21.7 0.0 0.0003 21.2 0.0 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH_2 PF08458.10 KFM26111.1 - 0.013 15.8 0.0 0.015 15.6 0.0 1.1 1 0 0 1 1 1 0 Plant pleckstrin homology-like region PH_13 PF16652.5 KFM26111.1 - 0.052 13.4 0.0 0.057 13.2 0.0 1.1 1 0 0 1 1 1 0 Pleckstrin homology domain ketoacyl-synt PF00109.26 KFM26112.1 - 6.5e-62 209.4 13.9 1.8e-29 103.1 6.1 3.6 2 1 1 3 3 3 3 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KFM26112.1 - 4e-57 193.0 23.7 8.4e-25 87.7 1.3 5.0 4 1 0 4 4 4 3 KR domain PP-binding PF00550.25 KFM26112.1 - 1.8e-43 146.7 2.5 1.5e-12 47.7 0.0 4.5 4 0 0 4 4 4 4 Phosphopantetheine attachment site Ketoacyl-synt_C PF02801.22 KFM26112.1 - 4.2e-34 117.1 6.1 5e-17 62.0 0.4 3.3 2 0 0 2 2 2 2 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 KFM26112.1 - 3.8e-14 53.9 0.0 1.3e-13 52.2 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KFM26112.1 - 5.5e-06 26.4 0.2 2e-05 24.6 0.2 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 KFM26112.1 - 0.00016 22.1 0.2 0.045 14.2 0.0 3.0 3 0 0 3 3 3 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KFM26112.1 - 0.014 14.9 14.1 3.8 6.9 0.4 5.1 5 0 0 5 5 5 0 short chain dehydrogenase ketoacyl-synt PF00109.26 KFM26115.1 - 4e-74 249.4 12.0 2.1e-42 145.5 1.3 3.6 2 1 1 3 3 3 3 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KFM26115.1 - 4.8e-44 149.2 10.8 2.8e-24 85.4 1.7 2.7 2 0 0 2 2 2 2 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 KFM26115.1 - 2.5e-38 131.8 4.0 2.4e-24 86.2 0.1 2.5 2 0 0 2 2 2 2 KR domain PP-binding PF00550.25 KFM26115.1 - 1.4e-37 127.8 2.4 6.3e-14 52.1 0.0 3.5 3 0 0 3 3 3 3 Phosphopantetheine attachment site Thiolase_N PF00108.23 KFM26115.1 - 0.0017 17.7 0.6 0.0017 17.7 0.6 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain PS-DH PF14765.6 KFM26115.1 - 0.004 16.4 1.7 0.026 13.7 0.2 2.3 2 0 0 2 2 2 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 KFM26115.1 - 0.0096 16.4 0.1 0.025 15.1 0.1 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Ketoacyl-synt_C PF02801.22 KFM26116.1 - 1.3e-43 147.7 0.9 6.4e-26 90.7 0.0 2.8 2 0 0 2 2 2 2 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 KFM26116.1 - 1.5e-18 67.3 3.5 2.8e-09 36.9 0.1 3.5 2 1 2 4 4 4 2 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KFM26116.1 - 3.2e-18 66.3 3.5 8.5e-18 64.9 3.5 1.7 1 1 0 1 1 1 1 KR domain PP-binding PF00550.25 KFM26116.1 - 1e-11 45.0 0.0 2.2e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site PS-DH PF14765.6 KFM26116.1 - 0.00055 19.3 0.1 0.00098 18.4 0.1 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase TPR_12 PF13424.6 KFM26116.1 - 0.51 10.7 2.8 1.6 9.0 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_hydro_47 PF01532.20 KFM26117.1 - 3.7e-108 362.4 0.0 2.8e-59 201.2 0.0 3.0 2 1 0 2 2 2 2 Glycosyl hydrolase family 47 Cpn60_TCP1 PF00118.24 KFM26118.1 - 5.6e-147 490.3 7.2 6.5e-147 490.1 7.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DnaJ PF00226.31 KFM26119.1 - 5.9e-24 84.0 1.9 1.2e-23 83.0 1.9 1.5 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.11 KFM26119.1 - 6.6e-16 58.5 4.3 1.4e-15 57.4 4.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) 2CSK_N PF08521.10 KFM26119.1 - 0.053 13.6 0.0 0.098 12.8 0.0 1.4 1 0 0 1 1 1 0 Two-component sensor kinase N-terminal TPR_14 PF13428.6 KFM26119.1 - 0.091 13.6 1.2 1.6 9.7 0.0 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFM26119.1 - 0.14 12.3 0.1 0.14 12.3 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.25 KFM26120.1 - 1.7e-43 148.9 0.0 2.2e-43 148.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM26120.1 - 4.5e-21 75.3 0.0 5.5e-21 75.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Peptidase_M16_M PF16187.5 KFM26121.1 - 5.8e-73 245.6 0.0 7.6e-73 245.2 0.0 1.2 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 KFM26121.1 - 2.6e-20 72.9 0.0 2.6e-15 56.7 0.0 2.5 1 1 1 2 2 2 2 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KFM26121.1 - 1.7e-18 67.3 0.0 7.6e-13 48.9 0.0 2.5 2 0 0 2 2 2 2 Peptidase M16 inactive domain DNA_circ_N PF07157.12 KFM26121.1 - 0.08 13.3 0.2 30 5.1 0.0 3.6 4 0 0 4 4 4 0 DNA circularisation protein N-terminus WCCH PF03716.14 KFM26123.1 - 0.013 15.2 0.1 8.7 6.1 0.0 2.8 2 0 0 2 2 2 0 WCCH motif DUF4346 PF14251.6 KFM26123.1 - 0.11 12.5 0.1 17 5.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4346) NUDIX_2 PF13869.6 KFM26124.1 - 1.4e-50 171.5 0.1 5.5e-48 163.1 0.1 2.3 1 1 0 1 1 1 1 Nucleotide hydrolase Beta_helix PF13229.6 KFM26125.1 - 8.5e-08 32.2 0.0 1.4e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 KFM26125.1 - 2.1e-06 27.2 0.0 3.1e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) TPR_1 PF00515.28 KFM26125.1 - 0.0018 18.0 0.5 0.0018 18.0 0.5 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFM26125.1 - 0.0045 17.0 18.2 0.011 15.8 1.3 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFM26125.1 - 0.35 11.0 8.3 4.8 7.4 0.4 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFM26125.1 - 0.98 10.2 9.0 6.5 7.6 3.3 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 KFM26125.1 - 1.5 9.0 14.5 0.096 12.8 8.6 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFM26125.1 - 1.7 9.0 15.7 0.56 10.5 7.9 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFM26125.1 - 7.8 7.6 28.7 0.68 10.9 5.5 4.1 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFM26125.1 - 9.8 6.8 11.9 3 8.4 3.2 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat COG7 PF10191.9 KFM26126.1 - 9.7e-51 172.9 0.0 1.1e-15 57.0 0.0 4.6 1 1 3 4 4 4 4 Golgi complex component 7 (COG7) COG2 PF06148.11 KFM26126.1 - 0.00059 19.9 0.3 0.0035 17.4 0.3 2.4 1 1 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF4081 PF13312.6 KFM26126.1 - 0.026 14.7 1.7 6.2 7.1 0.3 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4081) DASH_Dad3 PF08656.10 KFM26126.1 - 0.045 13.8 0.7 25 5.0 0.0 3.4 2 1 1 3 3 3 0 DASH complex subunit Dad3 T3SS_basalb_I PF17001.5 KFM26126.1 - 0.075 13.6 0.3 15 6.2 0.1 3.0 2 2 0 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI HSBP1 PF06825.12 KFM26126.1 - 0.1 12.5 0.1 0.98 9.3 0.0 2.6 3 0 0 3 3 3 0 Heat shock factor binding protein 1 GTP_EFTU PF00009.27 KFM26128.1 - 1.2e-44 152.1 0.1 2e-44 151.5 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KFM26128.1 - 1.6e-13 50.9 0.3 5.1e-12 46.0 0.2 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 KFM26128.1 - 3.9e-13 49.7 0.0 3e-12 46.8 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KFM26128.1 - 1.8e-05 24.8 0.0 0.0062 16.6 0.0 3.1 3 1 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 KFM26128.1 - 0.0066 16.3 0.2 0.025 14.5 0.2 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Snf7 PF03357.21 KFM26129.1 - 1e-37 129.4 14.8 1.7e-20 73.3 1.8 2.0 2 0 0 2 2 2 2 Snf7 Prefoldin_2 PF01920.20 KFM26129.1 - 0.007 16.3 7.0 1.2 9.1 0.0 3.2 3 0 0 3 3 3 2 Prefoldin subunit Atg14 PF10186.9 KFM26129.1 - 0.037 13.1 6.5 0.032 13.3 5.1 1.5 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 WXG100 PF06013.12 KFM26129.1 - 0.11 12.8 5.0 7.6 6.9 5.1 3.1 2 1 0 2 2 2 0 Proteins of 100 residues with WXG Myotub-related PF06602.14 KFM26129.1 - 0.15 10.9 1.2 0.27 10.1 1.1 1.4 1 1 0 1 1 1 0 Myotubularin-like phosphatase domain Phage_lysozyme PF00959.19 KFM26129.1 - 0.22 12.0 1.4 0.45 11.0 1.2 1.6 1 1 0 1 1 1 0 Phage lysozyme OmpH PF03938.14 KFM26129.1 - 0.23 11.8 10.3 0.11 12.9 4.6 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Prefoldin PF02996.17 KFM26129.1 - 0.53 10.2 7.1 4.5 7.2 0.1 3.4 3 1 0 3 3 3 0 Prefoldin subunit AP1AR PF15745.5 KFM26129.1 - 1.4 8.5 8.7 0.045 13.4 2.2 1.7 2 1 0 2 2 2 0 AP-1 complex-associated regulatory protein BORCS8 PF10167.9 KFM26129.1 - 2.1 8.3 8.6 0.57 10.1 1.1 2.8 2 1 1 3 3 3 0 BLOC-1-related complex sub-unit 8 NUDIX PF00293.28 KFM26130.1 - 1.4e-14 54.2 0.0 2.6e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain MFS_1 PF07690.16 KFM26132.1 - 4.4e-42 144.3 61.0 6e-41 140.5 56.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM26132.1 - 0.0002 20.3 7.4 0.0002 20.3 7.4 2.0 1 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KFM26132.1 - 1.1 7.5 4.2 6.3 5.0 0.3 2.7 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family PTPLA PF04387.14 KFM26133.1 - 1.5e-46 158.1 4.8 2.3e-46 157.6 4.8 1.2 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Rubis-subs-bind PF09273.11 KFM26134.1 - 1.1e-09 39.1 0.0 1.8e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 KFM26134.1 - 3.4e-07 30.8 0.0 5e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 SET domain SRAP PF02586.14 KFM26135.1 - 4.1e-62 209.6 0.0 5.3e-62 209.2 0.0 1.1 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) cobW PF02492.19 KFM26136.1 - 4.1e-56 189.4 1.9 5.6e-56 188.9 1.9 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KFM26136.1 - 3.5e-20 71.7 0.0 5.9e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 KFM26136.1 - 0.0023 17.9 1.3 0.44 10.4 0.1 2.5 2 1 0 2 2 2 1 RsgA GTPase Viral_helicase1 PF01443.18 KFM26136.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 KFM26136.1 - 0.011 15.7 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KFM26136.1 - 0.011 15.7 0.1 0.029 14.4 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KFM26136.1 - 0.012 16.0 0.0 0.028 14.8 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 KFM26136.1 - 0.018 14.1 0.2 0.029 13.4 0.2 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 KFM26136.1 - 0.026 15.0 0.2 0.051 14.1 0.2 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KFM26136.1 - 0.027 14.2 0.1 0.06 13.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KFM26136.1 - 0.028 14.7 0.1 0.068 13.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KFM26136.1 - 0.04 14.0 0.2 0.22 11.6 0.2 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.6 KFM26136.1 - 0.059 13.9 0.0 0.18 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KFM26136.1 - 0.077 12.7 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFM26136.1 - 0.1 13.1 0.0 0.16 12.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Thioredoxin_12 PF18400.1 KFM26136.1 - 0.15 11.9 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain MobB PF03205.14 KFM26136.1 - 0.17 11.8 0.5 0.36 10.7 0.1 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 KFM26136.1 - 0.34 10.8 4.4 0.64 9.9 0.4 2.7 2 1 1 3 3 3 0 NTPase Vac14_Fig4_bd PF11916.8 KFM26137.1 - 3.1e-33 114.9 0.9 4.8e-33 114.3 0.9 1.2 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 KFM26137.1 - 1.2e-28 99.6 0.0 2.9e-28 98.3 0.0 1.7 1 0 0 1 1 1 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KFM26137.1 - 2.9e-07 30.8 17.8 0.0023 18.4 0.2 6.6 5 1 0 5 5 5 2 HEAT-like repeat HEAT PF02985.22 KFM26137.1 - 4.5e-06 26.5 22.7 0.00073 19.6 0.0 8.1 9 0 0 9 9 9 2 HEAT repeat HEAT_2 PF13646.6 KFM26137.1 - 0.00021 21.6 21.3 0.054 13.9 0.1 6.1 5 2 1 6 6 6 2 HEAT repeats MMS19_C PF12460.8 KFM26137.1 - 0.0023 17.1 0.0 0.34 10.0 0.0 3.2 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal XPC-binding PF09280.11 KFM26137.1 - 0.007 16.1 3.1 1.2 9.0 0.3 4.1 4 0 0 4 4 4 1 XPC-binding domain Cnd1 PF12717.7 KFM26137.1 - 0.026 14.5 0.0 4.1 7.4 0.0 3.3 3 1 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Tti2 PF10521.9 KFM26137.1 - 0.12 11.9 0.0 0.86 9.1 0.0 2.2 2 0 0 2 2 2 0 Tti2 family Adaptin_N PF01602.20 KFM26137.1 - 0.13 10.8 0.0 0.31 9.6 0.0 1.5 2 0 0 2 2 2 0 Adaptin N terminal region Sortilin-Vps10 PF15902.5 KFM26139.1 - 2.3e-57 194.8 0.0 3.3e-57 194.3 0.0 1.1 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, BNR PF02012.20 KFM26139.1 - 5.6e-07 28.6 12.5 1.7 9.0 0.0 5.9 5 0 0 5 5 5 4 BNR/Asp-box repeat Ribosomal_TL5_C PF14693.6 KFM26140.1 - 1.4e-22 79.9 0.2 6e-21 74.6 0.1 2.4 2 0 0 2 2 2 2 Ribosomal protein TL5, C-terminal domain Cupin_8 PF13621.6 KFM26141.1 - 8e-49 166.6 0.0 6.6e-34 117.8 0.0 2.0 1 1 1 2 2 2 2 Cupin-like domain JmjC PF02373.22 KFM26141.1 - 7.9e-05 23.1 0.0 0.026 14.9 0.0 2.2 1 1 1 2 2 2 2 JmjC domain, hydroxylase Cupin_2 PF07883.11 KFM26141.1 - 0.00038 20.1 0.1 0.0012 18.6 0.1 1.8 1 1 0 1 1 1 1 Cupin domain Cupin_4 PF08007.12 KFM26141.1 - 0.14 11.6 0.1 0.24 10.8 0.1 1.5 1 1 0 1 1 1 0 Cupin superfamily protein Cupin_1 PF00190.22 KFM26141.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 Cupin CTD_bind PF04818.13 KFM26142.1 - 8.3e-10 39.4 0.0 1.5e-09 38.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Rhomboid PF01694.22 KFM26142.1 - 0.0049 16.9 7.1 0.011 15.7 7.1 1.6 1 0 0 1 1 1 1 Rhomboid family Surp PF01805.20 KFM26142.1 - 0.011 15.8 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Surp module DUF1751 PF08551.10 KFM26142.1 - 0.2 12.2 0.2 0.2 12.2 0.2 1.8 2 0 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) NADH5_C PF06455.11 KFM26142.1 - 9.4 5.8 5.4 83 2.7 0.1 3.0 3 0 0 3 3 3 0 NADH dehydrogenase subunit 5 C-terminus BSD PF03909.17 KFM26143.1 - 2.8e-16 59.3 0.9 4.3e-10 39.4 0.5 2.4 2 0 0 2 2 2 2 BSD domain SseB_C PF14581.6 KFM26143.1 - 0.079 13.1 0.0 2.1 8.5 0.0 2.3 2 0 0 2 2 2 0 SseB protein C-terminal domain Rubis-subs-bind PF09273.11 KFM26144.1 - 4.9e-11 43.4 1.5 5.2e-08 33.7 0.6 2.4 2 0 0 2 2 2 2 Rubisco LSMT substrate-binding SET PF00856.28 KFM26144.1 - 0.034 14.6 0.0 4.2 7.7 0.0 2.3 1 1 0 2 2 2 0 SET domain PNKP-ligase_C PF16536.5 KFM26144.1 - 0.087 13.1 0.2 0.18 12.1 0.2 1.5 1 0 0 1 1 1 0 PNKP adenylyltransferase domain, C-terminal region Tetraspanin PF00335.20 KFM26145.1 - 0.96 9.1 4.8 1.9 8.1 1.4 2.1 1 1 1 2 2 2 0 Tetraspanin family DUF1294 PF06961.13 KFM26145.1 - 4.2 7.7 5.3 0.67 10.2 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1294) SRP40_C PF05022.12 KFM26149.1 - 6.4e-25 87.8 4.0 8.4e-25 87.4 4.0 1.2 1 0 0 1 1 1 1 SRP40, C-terminal domain DUF3752 PF12572.8 KFM26150.1 - 1.3e-13 51.7 0.1 1.3e-13 51.7 0.1 3.1 3 1 0 3 3 3 1 Protein of unknown function (DUF3752) DnaJ PF00226.31 KFM26150.1 - 1.1e-12 47.9 0.0 2.1e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain AP3D1 PF06375.11 KFM26150.1 - 8.7 6.6 14.6 6.3 7.0 9.7 2.4 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 TPH PF13868.6 KFM26152.1 - 2.3e-08 33.0 80.8 2e-06 26.6 49.3 2.0 1 1 1 2 2 2 2 Trichohyalin-plectin-homology domain Peptidase_S64 PF08192.11 KFM26152.1 - 8.7 4.7 7.3 11 4.3 7.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 PI3_PI4_kinase PF00454.27 KFM26153.1 - 3.5e-45 154.8 0.0 2.1e-30 106.4 0.0 2.2 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KFM26153.1 - 3.4e-39 134.2 0.0 6.3e-39 133.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 KFM26153.1 - 7e-19 68.1 0.0 1.1e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Ank_2 PF12796.7 KFM26154.1 - 0.00013 22.4 0.0 0.00016 22.1 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM26154.1 - 0.00019 21.9 0.0 0.00025 21.5 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFM26154.1 - 0.015 15.6 0.0 0.021 15.1 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM26154.1 - 0.043 14.4 0.0 9.6 7.2 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat HSP70 PF00012.20 KFM26155.1 - 9.2e-73 245.4 0.0 2.8e-72 243.8 0.0 1.7 1 1 0 1 1 1 1 Hsp70 protein CysA_C_terminal PF17850.1 KFM26155.1 - 0.04 14.5 0.2 0.27 11.8 0.2 2.6 1 0 0 1 1 1 0 CysA C-terminal regulatory domain DHHA1 PF02272.19 KFM26156.1 - 4.4e-05 23.9 3.2 7.3e-05 23.2 3.2 1.3 1 0 0 1 1 1 1 DHHA1 domain DHH PF01368.20 KFM26156.1 - 0.004 17.4 0.0 0.007 16.6 0.0 1.4 1 0 0 1 1 1 1 DHH family FAD_binding_1 PF00667.20 KFM26157.1 - 1.7e-56 191.3 0.0 2.4e-56 190.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KFM26157.1 - 5.9e-20 71.9 0.1 1e-19 71.2 0.1 1.3 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KFM26157.1 - 2.3e-15 57.1 0.0 4.8e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain acVLRF1 PF18859.1 KFM26157.1 - 3.5 7.9 6.1 2.6 8.3 0.1 2.7 2 1 0 2 2 2 0 Actinobacteria/chloroflexi VLRF1 release factor Ofd1_CTDD PF10637.9 KFM26158.1 - 1.5e-61 208.0 0.0 7.2e-58 195.9 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 KFM26158.1 - 2.4e-23 82.6 0.0 4.7e-23 81.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KFM26158.1 - 3.7e-12 47.0 0.0 8.3e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HMG_box PF00505.19 KFM26159.1 - 4.5e-26 91.1 1.8 8.9e-26 90.1 1.8 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box Rtt106 PF08512.12 KFM26159.1 - 2.5e-20 72.6 0.0 4.8e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 Histone chaperone Rttp106-like HMG_box_2 PF09011.10 KFM26159.1 - 1.3e-17 64.1 3.5 3.2e-17 62.9 3.5 1.7 1 0 0 1 1 1 1 HMG-box domain POB3_N PF17292.2 KFM26159.1 - 1.7e-16 60.4 0.0 3e-14 53.2 0.0 2.8 3 0 0 3 3 3 1 POB3-like N-terminal PH domain SSrecog PF03531.14 KFM26159.1 - 2.4e-15 56.2 0.0 9.1e-15 54.3 0.0 2.0 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) CNDH2_C PF16858.5 KFM26159.1 - 0.1 12.4 11.3 0.14 12.0 11.3 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term PH_TFIIH PF08567.11 KFM26159.1 - 0.11 12.9 0.0 0.5 10.7 0.0 2.1 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain Sld5 PF05916.11 KFM26162.1 - 1.4e-07 31.9 0.0 2.8e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 GINS complex protein UvrD_C_2 PF13538.6 KFM26163.1 - 2e-17 62.8 0.2 4.7e-17 61.6 0.2 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 KFM26163.1 - 3.6e-17 62.7 0.1 1.5e-16 60.7 0.1 2.1 1 0 0 1 1 1 1 AAA domain SH3_13 PF18335.1 KFM26163.1 - 9.7e-15 54.2 0.0 1.5e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent RecD-like DNA helicase SH3 domain AAA_19 PF13245.6 KFM26163.1 - 4.2e-10 40.1 0.0 9.3e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain HHH_4 PF14490.6 KFM26163.1 - 8.6e-09 35.3 0.0 2.5e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix containing domain Viral_helicase1 PF01443.18 KFM26163.1 - 1.1e-07 31.9 0.0 0.00015 21.6 0.0 2.2 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase HHH_5 PF14520.6 KFM26163.1 - 1.6e-07 31.8 0.2 8.6e-07 29.5 0.1 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix domain UvrD_C PF13361.6 KFM26163.1 - 0.0015 18.0 0.1 0.0025 17.2 0.1 1.3 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain HHH PF00633.23 KFM26163.1 - 0.0033 17.2 1.2 2.8 8.0 0.1 2.7 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_2 PF12826.7 KFM26163.1 - 0.033 14.3 0.0 0.091 12.9 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif AAA_11 PF13086.6 KFM26163.1 - 0.054 13.3 1.0 0.085 12.6 1.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_12 PF13087.6 KFM26163.1 - 0.097 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain TP6A_N PF04406.14 KFM26164.1 - 3.8e-11 42.8 0.0 7.5e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF2399 PF09664.10 KFM26164.1 - 0.036 14.0 0.0 0.071 13.0 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function C-terminus (DUF2399) MAPEG PF01124.18 KFM26165.1 - 8.2e-20 71.0 1.0 1e-19 70.7 1.0 1.1 1 0 0 1 1 1 1 MAPEG family TMEM144 PF07857.12 KFM26166.1 - 9.1e-06 24.9 5.3 1.3e-05 24.4 5.3 1.2 1 0 0 1 1 1 1 Transmembrane family, TMEM144 of transporters WD40 PF00400.32 KFM26169.1 - 2.9e-19 69.0 0.4 2.3e-06 28.2 0.0 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 KFM26169.1 - 7.2e-08 32.6 0.1 5.7e-07 29.7 0.0 2.3 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 KFM26169.1 - 8.1e-05 22.8 0.0 0.15 12.4 0.0 2.5 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFM26169.1 - 0.0016 18.3 0.0 0.0028 17.5 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A PIN_4 PF13638.6 KFM26171.1 - 2.1e-14 53.9 0.0 4.3e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 PIN domain GYF PF02213.16 KFM26171.1 - 0.00017 21.2 0.1 0.00025 20.7 0.1 1.3 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 KFM26171.1 - 0.049 13.4 0.2 0.14 12.0 0.2 1.8 1 0 0 1 1 1 0 GYF domain 2 PIN_9 PF18477.1 KFM26171.1 - 0.18 12.1 0.1 0.43 10.9 0.1 1.7 1 0 0 1 1 1 0 PIN like domain WD40 PF00400.32 KFM26172.1 - 2.2e-52 173.9 20.2 3.1e-07 31.0 0.0 11.0 11 0 0 11 11 11 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM26172.1 - 4.7e-14 52.4 0.3 0.21 11.9 0.0 6.8 2 2 5 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 KFM26172.1 - 4.4e-11 43.0 0.0 6.9e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 KFM26172.1 - 1.3e-07 30.9 2.2 1.2 8.0 0.0 6.4 3 2 3 7 7 7 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KFM26172.1 - 0.00064 18.5 0.2 4.1 5.9 0.0 4.6 4 1 1 5 5 5 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KFM26172.1 - 0.004 16.0 0.0 0.27 9.9 0.0 3.6 3 1 2 5 5 5 1 Nup133 N terminal like WD40_like PF17005.5 KFM26172.1 - 0.015 14.6 0.0 0.35 10.2 0.0 2.7 3 1 1 4 4 4 0 WD40-like domain PALB2_WD40 PF16756.5 KFM26172.1 - 0.14 11.1 10.3 1.8 7.4 0.2 4.3 5 1 1 6 6 6 0 Partner and localizer of BRCA2 WD40 domain PLAT PF01477.23 KFM26173.1 - 3.2e-45 153.5 0.0 3.8e-13 50.0 0.0 8.2 8 1 1 9 9 9 6 PLAT/LH2 domain PPR_3 PF13812.6 KFM26173.1 - 1.7e-08 34.4 0.0 0.00094 19.2 0.0 2.3 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR_2 PF13041.6 KFM26173.1 - 7.9e-08 32.4 0.0 0.00053 20.1 0.0 3.0 2 2 1 3 3 3 3 PPR repeat family ATS3 PF06232.11 KFM26173.1 - 3.9e-05 23.5 0.0 0.015 15.2 0.0 3.5 4 0 0 4 4 4 1 Embryo-specific protein 3, (ATS3) PPR PF01535.20 KFM26173.1 - 0.00013 22.0 0.0 0.48 10.8 0.0 4.0 4 0 0 4 4 4 1 PPR repeat Phage_r1t_holin PF16945.5 KFM26173.1 - 0.13 12.5 0.4 0.83 9.9 0.4 2.4 1 0 0 1 1 1 0 Putative lactococcus lactis phage r1t holin PPR_1 PF12854.7 KFM26173.1 - 0.13 12.0 0.0 46 3.8 0.0 3.6 4 0 0 4 4 4 0 PPR repeat DUF1279 PF06916.13 KFM26174.1 - 1.9e-11 44.3 0.0 3.7e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Ran_BP1 PF00638.18 KFM26174.1 - 1.8e-05 25.0 0.0 3.7e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 RanBP1 domain adh_short PF00106.25 KFM26175.1 - 1.1e-40 139.2 0.1 1.6e-40 138.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM26175.1 - 1.6e-30 106.4 0.3 2e-30 106.1 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM26175.1 - 7.6e-06 26.0 0.0 1.2e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF5612 PF18462.1 KFM26175.1 - 0.1 12.4 0.4 0.21 11.4 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5612) MRP-L28 PF09812.9 KFM26176.1 - 0.0002 21.6 0.4 0.00025 21.2 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 N_NLPC_P60 PF12912.7 KFM26176.1 - 0.11 12.9 0.3 3 8.2 0.0 2.5 1 1 2 3 3 3 0 NLPC_P60 stabilising domain, N term PGM_PMM_I PF02878.16 KFM26177.1 - 8.4e-32 109.8 0.0 1.3e-31 109.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KFM26177.1 - 1.4e-28 99.4 0.0 2.7e-28 98.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KFM26177.1 - 9.9e-14 51.8 0.0 2.2e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KFM26177.1 - 7e-06 26.1 0.0 1.9e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain UL11 PF11094.8 KFM26178.1 - 0.091 12.7 0.5 0.23 11.4 0.5 1.6 1 0 0 1 1 1 0 Membrane-associated tegument protein FeThRed_B PF02943.15 KFM26179.1 - 8.9e-43 144.6 2.4 1.2e-42 144.2 2.4 1.2 1 0 0 1 1 1 1 Ferredoxin thioredoxin reductase catalytic beta chain RRM_1 PF00076.22 KFM26180.1 - 1.2e-25 89.2 0.0 1.8e-11 43.7 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KFM26180.1 - 6.7e-05 23.2 2.0 2.4 8.4 0.1 3.9 2 2 2 4 4 4 2 Cytosolic domain of 10TM putative phosphate transporter Nup35_RRM_2 PF14605.6 KFM26180.1 - 0.00014 21.8 0.0 0.046 13.7 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KFM26180.1 - 0.0045 16.8 0.0 0.76 9.7 0.0 2.3 2 0 0 2 2 2 2 Occluded RNA-recognition motif Nup35_RRM PF05172.13 KFM26180.1 - 0.019 14.9 0.0 8.5 6.4 0.0 2.5 2 1 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Aminotran_4 PF01063.19 KFM26181.1 - 3e-13 50.2 0.0 1.5e-11 44.6 0.0 2.1 2 0 0 2 2 2 2 Amino-transferase class IV DUF5558 PF17713.1 KFM26181.1 - 0.21 12.0 1.7 0.6 10.5 1.7 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5558) ATP12 PF07542.11 KFM26182.1 - 1e-37 129.1 0.0 1.4e-37 128.6 0.0 1.2 1 0 0 1 1 1 1 ATP12 chaperone protein Thioredoxin PF00085.20 KFM26183.1 - 8.5e-14 51.4 0.0 1.1e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KFM26183.1 - 5.2e-06 26.9 0.0 1.2e-05 25.7 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KFM26183.1 - 5.2e-06 26.7 0.0 1.1e-05 25.6 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.6 KFM26183.1 - 5.9e-06 26.4 0.1 1.7e-05 24.9 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 KFM26183.1 - 0.0011 18.9 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KFM26183.1 - 0.016 14.9 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Redoxin G-patch PF01585.23 KFM26184.1 - 5.6e-14 51.8 2.2 1.1e-13 50.9 2.2 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KFM26184.1 - 0.00027 20.9 0.6 0.00064 19.8 0.6 1.6 1 0 0 1 1 1 1 G-patch domain CAP_N PF01213.19 KFM26184.1 - 0.0012 18.4 1.4 0.0012 18.4 1.4 2.5 3 0 0 3 3 3 1 Adenylate cyclase associated (CAP) N terminal PPDFL PF15060.6 KFM26184.1 - 0.0062 17.0 0.0 0.018 15.5 0.0 1.8 1 0 0 1 1 1 1 Differentiation and proliferation regulator OGG_N PF07934.12 KFM26186.1 - 1.1e-28 99.7 0.0 1.5e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 KFM26186.1 - 2.8e-10 40.6 0.0 5.7e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KFM26186.1 - 0.0023 17.7 0.0 0.015 15.2 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif Transposase_20 PF02371.16 KFM26186.1 - 0.11 12.8 0.1 29 5.1 0.0 2.7 2 0 0 2 2 2 0 Transposase IS116/IS110/IS902 family EMC1_C PF07774.13 KFM26187.1 - 5.5e-48 163.5 0.0 7.3e-48 163.1 0.0 1.2 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 KFM26187.1 - 6e-09 35.8 10.5 3.2e-06 26.9 2.7 3.9 3 1 0 3 3 3 3 PQQ-like domain Cnd3 PF12719.7 KFM26188.1 - 4.5e-14 52.3 0.0 4.1e-13 49.2 0.0 2.5 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 KFM26188.1 - 0.00011 22.5 29.7 0.00053 20.3 10.1 6.8 5 2 2 7 7 7 2 HEAT repeats Birna_VP4 PF01768.16 KFM26188.1 - 0.33 10.7 1.8 0.74 9.6 1.8 1.5 1 0 0 1 1 1 0 Birnavirus VP4 protein Dor1 PF04124.12 KFM26189.1 - 4.4e-07 28.9 0.0 5.4e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Dor1-like family Dor1 PF04124.12 KFM26190.1 - 1.3e-31 109.6 0.0 9.4e-26 90.3 0.0 2.1 1 1 1 2 2 2 2 Dor1-like family Fe-ADH PF00465.19 KFM26190.1 - 0.049 12.4 3.4 0.045 12.6 1.5 1.7 2 0 0 2 2 2 0 Iron-containing alcohol dehydrogenase ABC_membrane PF00664.23 KFM26191.1 - 2.4e-54 184.8 6.2 4.4e-54 184.0 6.2 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KFM26191.1 - 2.4e-27 96.1 0.0 4.3e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KFM26191.1 - 1.8e-07 30.9 0.5 1.7e-05 24.4 0.0 2.1 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KFM26191.1 - 4.7e-05 23.8 1.7 4.7e-05 23.8 1.7 2.5 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KFM26191.1 - 0.0069 16.7 0.9 0.17 12.1 0.2 2.9 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFM26191.1 - 0.017 14.9 4.2 0.039 13.7 1.5 2.8 2 1 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 KFM26191.1 - 0.058 12.2 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA PF00004.29 KFM26191.1 - 0.081 13.3 0.1 21 5.5 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_PrkA PF08298.11 KFM26191.1 - 0.091 11.7 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain DUF5566 PF17721.1 KFM26191.1 - 0.13 12.5 0.7 0.23 11.7 0.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5566) Bunya_G2 PF03563.13 KFM26191.1 - 0.17 11.1 0.1 0.36 10.0 0.1 1.4 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 SbcCD_C PF13558.6 KFM26191.1 - 2.6 8.4 6.3 1.1 9.5 0.8 3.1 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RCC1 PF00415.18 KFM26192.1 - 1.3e-49 166.6 45.5 2.4e-13 50.5 1.0 8.9 7 2 1 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFM26192.1 - 1.1e-31 108.0 49.7 1.4e-09 37.5 1.1 7.5 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat Acetyltransf_1 PF00583.25 KFM26194.1 - 1e-09 38.7 0.0 2e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family TPR_1 PF00515.28 KFM26194.1 - 1e-08 34.6 9.0 0.0019 17.9 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFM26194.1 - 4.2e-08 32.7 13.5 0.00072 19.5 0.0 4.4 4 0 0 4 4 3 3 Tetratricopeptide repeat Acetyltransf_10 PF13673.7 KFM26194.1 - 7e-06 26.0 0.0 1.7e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFM26194.1 - 1.1e-05 25.8 0.0 2.6e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain TPR_11 PF13414.6 KFM26194.1 - 6.9e-05 22.5 4.8 0.12 12.1 1.6 2.6 2 0 0 2 2 2 2 TPR repeat FR47 PF08445.10 KFM26194.1 - 0.00065 19.6 0.0 0.0016 18.4 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein TPR_16 PF13432.6 KFM26194.1 - 0.0011 19.6 10.5 0.0011 19.6 10.5 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFM26194.1 - 0.0021 18.2 4.6 4.4 7.8 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFM26194.1 - 0.0033 17.3 6.9 0.19 11.8 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFM26194.1 - 0.0063 16.3 0.2 0.0063 16.3 0.2 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFM26194.1 - 0.017 15.4 15.7 0.083 13.2 0.1 4.2 3 1 0 4 4 3 0 Tetratricopeptide repeat PanZ PF12568.8 KFM26194.1 - 0.036 13.8 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ TPR_14 PF13428.6 KFM26194.1 - 0.077 13.9 1.0 0.077 13.9 1.0 5.9 5 1 1 6 6 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFM26194.1 - 0.11 12.6 0.0 0.32 11.1 0.0 1.8 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat Acetyltransf_9 PF13527.7 KFM26194.1 - 0.64 10.1 3.7 0.58 10.2 0.1 2.5 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain TPR_9 PF13371.6 KFM26194.1 - 0.99 9.6 21.3 0.087 13.0 8.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat NDUFB11 PF17250.2 KFM26195.1 - 6e-12 46.0 0.2 6.9e-12 45.8 0.2 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase 11 kDa subunit zf-ZPR1 PF03367.13 KFM26197.1 - 1.8e-19 70.2 0.0 2.5e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 ZPR1 zinc-finger domain DnaJ_CXXCXGXG PF00684.19 KFM26198.1 - 0.00017 21.9 8.2 0.033 14.5 2.5 2.7 2 1 1 3 3 3 3 DnaJ central domain Lar_restr_allev PF14354.6 KFM26198.1 - 0.034 14.5 5.3 0.61 10.5 0.1 3.1 2 2 1 3 3 3 0 Restriction alleviation protein Lar DUF1356 PF07092.12 KFM26198.1 - 0.049 12.9 0.1 3.8 6.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1356) Anti-TRAP PF15777.5 KFM26198.1 - 0.1 12.6 7.4 7.3 6.6 0.0 3.0 2 1 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Cytochrome_CBB3 PF13442.6 KFM26198.1 - 0.77 10.1 0.0 0.77 10.1 0.0 2.6 2 1 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III XRN_N PF03159.18 KFM26200.1 - 3.1e-93 311.7 0.0 4e-93 311.3 0.0 1.2 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 KFM26200.1 - 5.8e-91 305.7 0.8 1.7e-90 304.1 0.0 2.0 2 1 0 2 2 2 1 Xrn1 helical domain XRN1_D1 PF18332.1 KFM26200.1 - 3.5e-26 92.1 0.0 1.7e-25 89.9 0.0 1.9 1 1 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain SH3_12 PF18129.1 KFM26200.1 - 1.3e-09 38.0 0.1 2.8e-09 36.9 0.1 1.5 1 0 0 1 1 1 1 Xrn1 SH3-like domain XRN1_D2_D3 PF18334.1 KFM26200.1 - 0.11 12.7 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Exoribonuclease Xrn1 D2/D3 domain Glutaredoxin PF00462.24 KFM26201.1 - 1.1e-16 60.7 0.0 2e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 KFM26201.1 - 0.00084 19.7 0.0 0.001 19.4 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 KFM26201.1 - 0.0031 17.9 0.0 0.0053 17.2 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 KFM26201.1 - 0.005 16.9 0.0 0.014 15.5 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin domain GST_N_2 PF13409.6 KFM26201.1 - 0.021 15.1 0.0 0.031 14.6 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin PF00085.20 KFM26201.1 - 0.023 14.7 0.0 0.03 14.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin GST_N_3 PF13417.6 KFM26201.1 - 0.043 14.2 0.0 0.058 13.8 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DSBA PF01323.20 KFM26201.1 - 0.078 12.7 1.4 0.53 10.0 0.1 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_9 PF14595.6 KFM26201.1 - 0.14 12.0 0.0 0.19 11.5 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin ArfGap PF01412.18 KFM26202.1 - 3.1e-24 85.3 0.1 5.1e-23 81.4 0.1 2.1 1 1 0 1 1 1 1 Putative GTPase activating protein for Arf adh_short_C2 PF13561.6 KFM26203.1 - 1.2e-66 224.6 7.8 1.6e-66 224.2 7.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFM26203.1 - 7.7e-57 191.9 5.2 9e-57 191.7 5.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFM26203.1 - 3.2e-14 53.2 3.2 6.5e-14 52.2 3.2 1.4 1 0 0 1 1 1 1 KR domain Methyltransf_25 PF13649.6 KFM26203.1 - 0.02 15.6 0.3 0.054 14.2 0.3 1.8 1 1 0 1 1 1 0 Methyltransferase domain ADH_zinc_N PF00107.26 KFM26203.1 - 0.022 14.7 3.1 0.04 13.9 3.1 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Peptidase_C48 PF02902.19 KFM26204.1 - 1.8e-31 109.7 0.1 3.2e-31 108.8 0.1 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Glyco_hydro_4C PF11975.8 KFM26204.1 - 0.21 11.6 0.1 0.39 10.8 0.1 1.4 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain ER-remodelling PF14755.6 KFM26204.1 - 2.1 8.6 12.0 0.27 11.5 7.4 1.8 2 0 0 2 2 2 0 Intracellular membrane remodeller DUF3789 PF12664.7 KFM26205.1 - 0.078 12.7 3.7 0.15 11.8 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) AAA PF00004.29 KFM26207.1 - 3.9e-22 79.1 1.0 2.7e-16 60.2 0.0 2.4 1 1 1 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFM26207.1 - 0.00095 19.6 0.9 0.0028 18.0 0.4 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_lid_3 PF17862.1 KFM26207.1 - 0.002 17.9 0.0 0.0063 16.3 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KFM26207.1 - 0.0029 17.9 0.6 0.1 12.9 0.1 2.7 1 1 2 3 3 3 1 AAA domain AAA_5 PF07728.14 KFM26207.1 - 0.0031 17.5 2.6 0.13 12.2 0.3 2.8 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KFM26207.1 - 0.0073 15.7 0.0 0.017 14.5 0.0 1.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KFM26207.1 - 0.02 15.4 0.0 0.051 14.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KFM26207.1 - 0.024 14.3 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 KFM26207.1 - 0.042 13.5 0.6 0.14 11.9 0.0 2.2 3 0 0 3 3 3 0 AAA domain RuvB_N PF05496.12 KFM26207.1 - 0.061 13.1 0.5 1 9.1 0.1 2.3 1 1 1 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Vps4_C PF09336.10 KFM26207.1 - 0.12 12.4 0.0 0.74 9.9 0.0 2.4 4 0 0 4 4 4 0 Vps4 C terminal oligomerisation domain S4 PF01479.25 KFM26208.1 - 4.9e-12 45.4 1.3 4.9e-12 45.4 1.3 2.0 2 0 0 2 2 2 1 S4 domain VMA21 PF09446.10 KFM26209.1 - 2.6e-12 46.6 1.2 3.2e-12 46.4 1.2 1.1 1 0 0 1 1 1 1 VMA21-like domain DUF5345 PF17280.2 KFM26209.1 - 0.12 12.3 0.2 0.16 11.9 0.2 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5345) Snf7 PF03357.21 KFM26210.1 - 3.9e-39 134.0 16.7 4.6e-39 133.8 16.7 1.0 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.14 KFM26210.1 - 0.048 13.6 3.8 0.07 13.1 3.8 1.3 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway GAS PF13851.6 KFM26210.1 - 0.77 9.1 12.4 0.41 10.0 8.9 1.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Spc24 PF08286.11 KFM26210.1 - 1.3 9.3 8.3 8.2 6.7 0.6 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Seryl_tRNA_N PF02403.22 KFM26210.1 - 2.6 8.3 11.2 13 6.1 6.4 2.7 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain GST_N_3 PF13417.6 KFM26211.1 - 1.1e-30 105.9 0.0 3.9e-16 59.2 0.0 2.2 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KFM26211.1 - 1.2e-11 44.7 0.0 0.00011 22.4 0.0 2.3 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KFM26211.1 - 1.9e-09 37.7 0.0 0.0022 18.3 0.0 2.3 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 KFM26211.1 - 1e-07 32.0 0.2 1.9e-05 24.8 0.2 2.4 2 0 0 2 2 2 2 Glutaredoxin DRIM PF07539.12 KFM26212.1 - 1.7e-43 148.9 0.0 7.2e-24 84.0 0.0 4.8 3 1 1 4 4 4 3 Down-regulated in metastasis Cnd1 PF12717.7 KFM26212.1 - 0.014 15.4 1.0 0.56 10.2 0.1 3.0 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 NUC173 PF08161.12 KFM26212.1 - 0.18 11.4 0.2 17 5.0 0.0 3.4 3 0 0 3 3 3 0 NUC173 domain Adaptin_N PF01602.20 KFM26212.1 - 1.3 7.5 3.1 11 4.4 0.3 3.1 3 0 0 3 3 3 0 Adaptin N terminal region ABC_tran PF00005.27 KFM26214.1 - 8.7e-34 117.0 0.0 1.2e-33 116.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KFM26214.1 - 9.4e-10 38.8 0.0 0.00055 19.8 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system TOBE_2 PF08402.10 KFM26214.1 - 0.00017 21.7 0.0 0.00058 20.0 0.0 1.9 2 0 0 2 2 2 1 TOBE domain AAA_29 PF13555.6 KFM26214.1 - 0.00033 20.3 0.0 0.00067 19.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 KFM26214.1 - 0.0012 18.3 0.0 0.81 9.1 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KFM26214.1 - 0.0014 19.1 0.4 0.0026 18.2 0.4 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 KFM26214.1 - 0.0017 18.9 0.0 0.0025 18.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KFM26214.1 - 0.0054 17.0 0.1 0.031 14.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KFM26214.1 - 0.0072 16.2 0.0 0.019 14.9 0.0 1.6 2 0 0 2 2 2 1 RsgA GTPase ABC_ATPase PF09818.9 KFM26214.1 - 0.013 14.3 0.3 0.56 8.9 0.0 2.5 2 1 0 2 2 2 0 Predicted ATPase of the ABC class AAA_28 PF13521.6 KFM26214.1 - 0.024 14.9 0.3 0.31 11.3 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KFM26214.1 - 0.027 14.0 0.1 0.59 9.7 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KFM26214.1 - 0.038 14.1 0.2 0.2 11.8 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 KFM26214.1 - 0.041 13.6 0.0 0.08 12.6 0.0 1.4 2 0 0 2 2 2 0 AAA ATPase domain SbcCD_C PF13558.6 KFM26214.1 - 0.052 13.8 0.1 0.28 11.4 0.1 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 KFM26214.1 - 0.052 13.5 0.1 0.11 12.4 0.1 1.7 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 KFM26214.1 - 0.077 12.7 0.9 0.19 11.4 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KFM26214.1 - 0.1 13.0 0.0 0.21 12.0 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 KFM26214.1 - 0.13 11.8 0.4 0.27 10.8 0.4 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 KFM26214.1 - 0.15 12.6 0.0 0.4 11.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_5 PF07728.14 KFM26214.1 - 0.2 11.6 0.3 0.63 10.0 0.3 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 KFM26214.1 - 0.24 10.5 0.0 1.6 7.9 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain TFIIA_gamma_C PF02751.14 KFM26215.1 - 7.4e-12 45.2 0.0 1.1e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 KFM26215.1 - 1.5e-11 44.2 0.2 2.2e-11 43.6 0.2 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain MFS_1_like PF12832.7 KFM26216.1 - 2.9e-36 125.1 7.5 3.4e-36 124.9 7.5 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KFM26216.1 - 1.2e-12 47.5 48.5 2.9e-10 39.6 29.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 KFM26216.1 - 2e-10 40.3 2.8 2.6e-10 39.9 2.8 1.1 1 0 0 1 1 1 1 Nucleoside H+ symporter MFS_1_like PF12832.7 KFM26217.1 - 0.0058 15.5 1.0 0.01 14.7 1.0 1.3 1 1 0 1 1 1 1 MFS_1 like family Calponin PF00402.18 KFM26217.1 - 0.12 12.0 0.2 0.31 10.7 0.2 1.7 1 0 0 1 1 1 0 Calponin family repeat Usp PF00582.26 KFM26218.1 - 0.0057 17.2 0.0 0.013 16.0 0.0 1.7 1 1 0 1 1 1 1 Universal stress protein family Ribosomal_L6e PF01159.19 KFM26220.1 - 2.4e-33 115.0 0.1 4.1e-33 114.2 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L6e Glyco_hydro_77 PF02446.17 KFM26221.1 - 1.6e-142 475.7 0.0 2e-142 475.4 0.0 1.0 1 0 0 1 1 1 1 4-alpha-glucanotransferase Filamin PF00630.19 KFM26222.1 - 1.3e-14 54.9 0.0 2.3e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Filamin/ABP280 repeat Invasin_D3 PF09134.10 KFM26222.1 - 7.1e-06 26.3 0.0 2.2e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Invasin, domain 3 YtkA PF13115.6 KFM26222.1 - 0.0032 18.0 0.0 0.0073 16.9 0.0 1.6 1 0 0 1 1 1 1 YtkA-like Ribosomal_L35Ae PF01247.18 KFM26223.1 - 1.9e-44 149.7 0.7 2.1e-44 149.6 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 KFM26223.1 - 0.011 16.0 0.0 0.8 10.0 0.0 2.1 2 0 0 2 2 2 0 RimM N-terminal domain Ins134_P3_kin PF05770.11 KFM26224.1 - 8.9e-32 110.2 0.0 2.7e-16 59.7 0.0 2.2 2 0 0 2 2 2 2 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain Ins134_P3_kin_N PF17927.1 KFM26224.1 - 2.4e-16 59.9 0.0 4.4e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain zf-RING_2 PF13639.6 KFM26226.1 - 5.9e-05 23.3 3.9 5.9e-05 23.3 3.9 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KFM26226.1 - 0.00043 20.2 2.1 0.0011 18.9 2.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 KFM26226.1 - 0.016 15.0 7.3 0.034 13.9 7.3 1.6 1 0 0 1 1 1 0 RING-like zinc finger FHA PF00498.26 KFM26227.1 - 4.4e-09 36.6 0.0 7.9e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 FHA domain ASF1_hist_chap PF04729.13 KFM26228.1 - 1.6e-70 236.0 0.1 1.9e-70 235.8 0.1 1.0 1 0 0 1 1 1 1 ASF1 like histone chaperone Mito_carr PF00153.27 KFM26229.1 - 1.6e-76 252.3 4.0 3.9e-25 87.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein XPG_I PF00867.18 KFM26231.1 - 2.1e-14 53.6 0.0 4.2e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KFM26231.1 - 4.6e-06 27.0 0.0 1.2e-05 25.7 0.0 1.7 1 1 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 KFM26231.1 - 0.015 14.8 3.5 0.046 13.2 0.0 2.2 2 0 0 2 2 2 0 XPG domain containing Cpn10 PF00166.21 KFM26232.1 - 1.3e-28 98.9 0.0 1.4e-28 98.7 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit CTP_transf_1 PF01148.20 KFM26233.1 - 8.1e-71 238.9 17.3 1e-70 238.5 17.3 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Glyoxalase PF00903.25 KFM26234.1 - 3.6e-32 111.2 0.1 2.6e-17 63.2 0.0 2.1 1 1 1 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KFM26234.1 - 2.3e-11 43.9 0.0 0.00011 22.4 0.0 2.2 1 1 1 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KFM26234.1 - 0.00028 21.0 0.0 3.7 7.6 0.0 3.5 1 1 1 2 2 2 2 Glyoxalase-like domain CppA_N PF14506.6 KFM26234.1 - 0.024 14.7 0.0 6.6 6.8 0.0 2.4 2 0 0 2 2 2 0 CppA N-terminal TxDE PF18711.1 KFM26234.1 - 0.025 14.7 0.0 3.6 7.8 0.0 3.1 3 0 0 3 3 3 0 Toxoflavin-degrading enzyme Clavanin PF05452.11 KFM26234.1 - 0.3 11.3 1.7 14 6.0 0.2 2.4 2 0 0 2 2 2 0 Clavanin Mlo PF03094.15 KFM26236.1 - 3.2e-49 167.6 13.2 8.1e-28 97.0 7.7 3.1 2 1 0 2 2 2 2 Mlo family EF-hand_1 PF00036.32 KFM26238.1 - 1.3e-29 99.5 6.0 5.1e-07 28.8 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KFM26238.1 - 2.7e-26 91.8 0.3 1.1e-11 45.0 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFM26238.1 - 5.6e-26 88.2 7.1 5.4e-08 32.1 0.1 4.6 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 KFM26238.1 - 1.3e-20 71.9 7.9 0.00025 20.4 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KFM26238.1 - 7.3e-20 70.6 1.7 3.1e-09 36.6 0.1 3.2 2 1 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFM26238.1 - 8.9e-05 22.8 0.0 0.26 11.6 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KFM26238.1 - 9.2e-05 22.7 0.0 0.28 11.6 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain Toprim_2 PF13155.6 KFM26238.1 - 0.001 19.5 0.2 0.17 12.3 0.0 2.4 1 1 1 2 2 2 1 Toprim-like Toprim_4 PF13662.6 KFM26238.1 - 0.018 15.5 0.3 0.42 11.1 0.1 2.4 2 1 0 2 2 2 0 Toprim domain Rota_NSP3 PF01665.16 KFM26238.1 - 0.1 11.7 0.0 0.53 9.3 0.0 1.8 2 0 0 2 2 2 0 Rotavirus non-structural protein NSP3 Pyrophosphatase PF00719.19 KFM26242.1 - 4e-55 186.0 0.2 5.6e-55 185.5 0.2 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase EPL1 PF10513.9 KFM26242.1 - 7.9e-11 42.6 0.0 1.9e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 Enhancer of polycomb-like CLP_protease PF00574.23 KFM26243.1 - 4.1e-79 264.7 0.1 5.1e-79 264.4 0.1 1.1 1 0 0 1 1 1 1 Clp protease MEKHLA PF08670.11 KFM26244.1 - 7.3e-39 132.9 0.0 8.1e-39 132.8 0.0 1.0 1 0 0 1 1 1 1 MEKHLA domain Zip PF02535.22 KFM26245.1 - 1.8e-39 135.9 0.1 2.4e-39 135.5 0.1 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter SHMT PF00464.19 KFM26246.1 - 1.2e-197 656.4 0.0 1.5e-197 656.0 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 KFM26246.1 - 0.097 11.9 0.0 0.19 11.0 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase Macro PF01661.21 KFM26246.1 - 0.14 12.2 0.1 30 4.7 0.0 3.7 4 0 0 4 4 4 0 Macro domain Gp_dh_C PF02800.20 KFM26247.1 - 8.4e-66 220.4 0.3 1.3e-65 219.9 0.3 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KFM26247.1 - 7.8e-32 109.6 0.0 1.6e-31 108.6 0.0 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KFM26247.1 - 0.12 11.8 0.1 0.21 10.9 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ribosomal_L5e PF17144.4 KFM26248.1 - 4.3e-81 270.7 0.1 4.3e-81 270.7 0.1 1.6 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 KFM26248.1 - 3.6e-32 111.2 4.6 3.6e-32 111.2 4.6 1.7 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region DUF2423 PF10338.9 KFM26248.1 - 0.73 10.1 5.0 1.6 9.0 5.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2423) HNOB PF07700.15 KFM26250.1 - 0.14 12.1 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 Haem-NO-binding DTW PF03942.15 KFM26252.1 - 6e-25 88.1 0.0 7.4e-25 87.8 0.0 1.0 1 0 0 1 1 1 1 DTW domain YdaS_antitoxin PF15943.5 KFM26253.1 - 0.012 15.5 0.0 0.06 13.2 0.0 2.0 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Cation_efflux PF01545.21 KFM26254.1 - 3.7e-33 114.9 4.9 5.2e-33 114.5 4.9 1.2 1 0 0 1 1 1 1 Cation efflux family NUC173 PF08161.12 KFM26255.1 - 8.1e-22 77.9 0.0 3.1e-21 76.0 0.0 2.0 3 0 0 3 3 3 1 NUC173 domain HEAT PF02985.22 KFM26255.1 - 0.066 13.5 5.3 1.4 9.3 0.0 4.5 5 0 0 5 5 5 0 HEAT repeat mTERF PF02536.14 KFM26256.1 - 0.00068 18.7 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 mTERF RuvA_C PF07499.13 KFM26256.1 - 0.094 13.2 0.2 0.24 11.9 0.0 1.7 2 0 0 2 2 2 0 RuvA, C-terminal domain Tox-HNH-HHH PF15637.6 KFM26256.1 - 0.12 12.5 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif TAFII55_N PF04658.13 KFM26257.1 - 4.6e-21 75.2 0.0 2.9e-19 69.3 0.0 2.0 1 1 0 1 1 1 1 TAFII55 protein conserved region S1 PF00575.23 KFM26258.1 - 0.00084 19.6 0.0 0.12 12.7 0.0 2.2 2 0 0 2 2 2 2 S1 RNA binding domain RRM_DME PF15628.6 KFM26259.1 - 7.5e-25 87.1 0.0 5.6e-24 84.3 0.0 2.1 2 0 0 2 2 2 1 RRM in Demeter DnaJ PF00226.31 KFM26259.1 - 3.4e-06 27.1 0.0 7.4e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain HhH-GPD PF00730.25 KFM26259.1 - 0.00024 21.5 0.0 0.00063 20.2 0.0 1.7 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Barttin PF15462.6 KFM26259.1 - 0.13 12.0 0.1 5.2 6.8 0.0 2.5 2 1 0 2 2 2 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) FAD-oxidase_C PF02913.19 KFM26260.1 - 2.7e-47 161.5 0.1 4.3e-47 160.9 0.1 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KFM26260.1 - 4.2e-27 94.6 0.0 9.1e-27 93.5 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Fer4_8 PF13183.6 KFM26260.1 - 4.9e-09 36.5 2.5 1.5e-08 34.9 2.5 1.9 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 KFM26260.1 - 6.5e-08 33.0 2.2 2.1e-07 31.4 2.2 2.0 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 KFM26260.1 - 9.9e-07 29.2 3.3 2.3e-06 28.0 3.3 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KFM26260.1 - 0.00067 20.5 3.4 0.0017 19.3 3.4 1.7 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 KFM26260.1 - 0.00093 19.3 4.6 0.52 10.5 0.5 2.7 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 KFM26260.1 - 0.016 15.3 3.0 2 8.6 0.4 3.0 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 KFM26260.1 - 0.099 12.8 7.0 0.53 10.5 1.4 2.5 1 1 2 3 3 3 0 4Fe-4S dicluster domain DUF3783 PF12646.7 KFM26260.1 - 0.15 12.0 0.0 16 5.6 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3783) Fer4 PF00037.27 KFM26260.1 - 0.16 11.9 14.3 0.056 13.3 1.9 3.0 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_22 PF17179.4 KFM26260.1 - 1.2 10.1 4.3 26 5.8 0.1 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_20 PF14691.6 KFM26260.1 - 1.7 8.4 5.8 0.24 11.2 0.1 2.2 2 0 0 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_2 PF12797.7 KFM26260.1 - 4.2 7.7 12.0 0.057 13.5 3.5 2.5 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_4 PF12800.7 KFM26260.1 - 6.1 7.6 10.8 0.16 12.6 2.6 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Aminotran_5 PF00266.19 KFM26261.1 - 7.4e-31 107.4 0.0 9.3e-31 107.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V PAS_9 PF13426.7 KFM26262.1 - 3.1e-28 98.1 0.0 7.2e-13 48.7 0.0 2.1 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 KFM26262.1 - 2.6e-10 40.5 0.5 1.2e-07 31.9 0.3 2.3 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 KFM26262.1 - 2.4e-07 31.0 0.0 0.024 14.9 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 KFM26262.1 - 2.9e-07 30.5 0.0 0.00033 20.6 0.0 2.4 2 0 0 2 2 2 2 PAS fold EGF_MSP1_1 PF12946.7 KFM26262.1 - 0.49 10.5 3.0 3.8 7.6 0.0 2.7 3 0 0 3 3 3 0 MSP1 EGF domain 1 2-Hacid_dh_C PF02826.19 KFM26263.1 - 6.6e-46 155.9 0.0 4.3e-45 153.3 0.0 1.9 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFM26263.1 - 2.6e-15 56.3 0.0 3.3e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 KFM26263.1 - 0.12 13.0 0.0 0.26 11.9 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Aldedh PF00171.22 KFM26264.1 - 3e-13 49.1 0.3 9.1e-12 44.2 0.1 2.1 2 0 0 2 2 2 2 Aldehyde dehydrogenase family F1F0-ATPsyn_F PF10791.9 KFM26265.1 - 0.0089 16.5 0.1 0.0097 16.4 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.9 KFM26265.1 - 0.019 15.3 0.0 0.024 15.0 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f eIF3_N PF09440.10 KFM26266.1 - 5.7e-45 153.0 2.6 8.3e-45 152.5 1.2 2.0 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 KFM26266.1 - 1.5e-16 60.8 1.1 1.3e-15 57.8 0.0 2.5 2 1 0 2 2 2 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 KFM26266.1 - 0.0029 17.6 2.3 0.064 13.2 0.1 3.0 3 0 0 3 3 3 1 CSN8/PSMD8/EIF3K family RPN7 PF10602.9 KFM26266.1 - 0.046 13.4 0.0 0.14 11.8 0.0 1.9 2 0 0 2 2 2 0 26S proteasome subunit RPN7 DUF1682 PF07946.14 KFM26266.1 - 0.16 11.1 1.7 0.82 8.8 0.0 2.7 3 1 1 4 4 4 0 Protein of unknown function (DUF1682) TPR_20 PF14561.6 KFM26266.1 - 3.2 8.2 7.8 10 6.5 0.0 3.7 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF4079 PF13301.6 KFM26267.1 - 2e-42 144.7 0.0 3e-42 144.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4079) WSD PF15613.6 KFM26268.1 - 5.3e-11 42.9 0.1 3e-10 40.4 0.0 2.3 2 0 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif PHD PF00628.29 KFM26268.1 - 2.7e-05 24.0 1.1 4.8e-05 23.2 1.1 1.4 1 0 0 1 1 1 1 PHD-finger DDT PF02791.17 KFM26268.1 - 0.16 12.3 0.6 0.38 11.1 0.6 1.6 1 0 0 1 1 1 0 DDT domain Glyco_transf_24 PF18404.1 KFM26270.1 - 2.7e-139 463.1 2.4 4.1e-139 462.5 2.4 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 KFM26270.1 - 3.4e-29 102.6 0.0 6.4e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 KFM26270.1 - 3.8e-26 92.1 0.0 6.3e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 KFM26270.1 - 7e-21 74.4 0.0 1.4e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_13 PF18401.1 KFM26270.1 - 8.2e-17 61.4 0.3 5.7e-15 55.4 0.1 2.4 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 KFM26270.1 - 1.1e-16 61.4 0.0 2.1e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 KFM26270.1 - 0.00023 20.8 0.1 0.00036 20.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 eIF-5_eIF-2B PF01873.17 KFM26271.1 - 2.5e-38 130.5 0.0 4.1e-38 129.9 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 DTHCT PF08070.11 KFM26271.1 - 0.17 12.6 7.2 0.33 11.7 7.2 1.4 1 0 0 1 1 1 0 DTHCT (NUC029) region SPT6_acidic PF14632.6 KFM26271.1 - 0.17 12.5 11.9 0.43 11.2 11.9 1.7 1 1 0 1 1 1 0 Acidic N-terminal SPT6 CemA PF03040.14 KFM26272.1 - 1.5e-60 205.0 0.0 1.9e-60 204.7 0.0 1.1 1 0 0 1 1 1 1 CemA family DUF1997 PF09366.10 KFM26273.1 - 7.7e-32 110.6 0.0 9e-32 110.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1997) Glyco_transf_90 PF05686.12 KFM26274.1 - 2.6e-35 122.1 0.0 7.5e-15 54.7 0.0 3.9 3 1 0 3 3 3 3 Glycosyl transferase family 90 tRNA-synt_2 PF00152.20 KFM26276.1 - 4.4e-78 262.5 0.0 5.3e-78 262.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KFM26276.1 - 9.5e-12 44.7 0.0 3e-11 43.2 0.0 1.8 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KFM26276.1 - 2.7e-07 30.3 0.0 0.017 14.6 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) MatE PF01554.18 KFM26277.1 - 1.9e-35 121.9 24.6 2.4e-20 72.8 6.7 3.1 2 1 0 2 2 2 2 MatE MurJ PF03023.14 KFM26277.1 - 5.3e-09 35.2 4.7 5.3e-09 35.2 4.7 2.3 2 1 0 2 2 2 1 Lipid II flippase MurJ Polysacc_synt_C PF14667.6 KFM26277.1 - 5.2e-08 33.1 4.7 5.2e-08 33.1 4.7 3.8 3 1 1 4 4 4 1 Polysaccharide biosynthesis C-terminal domain DUF789 PF05623.12 KFM26278.1 - 8.2e-17 61.8 1.7 1e-15 58.2 0.6 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF789) Vac_ImportDeg PF09783.9 KFM26279.1 - 2e-43 148.0 0.0 2.4e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein FSH1 PF03959.13 KFM26280.1 - 1.1e-41 142.9 0.0 1.7e-41 142.2 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KFM26280.1 - 3.7e-07 30.2 0.0 7.8e-07 29.1 0.0 1.5 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase TFIID_30kDa PF03540.13 KFM26282.1 - 6e-16 58.1 0.0 1.4e-15 57.0 0.0 1.6 2 0 0 2 2 2 1 Transcription initiation factor TFIID 23-30kDa subunit Fe_hyd_lg_C PF02906.14 KFM26282.1 - 0.13 11.9 0.0 0.24 11.0 0.0 1.5 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain adh_short PF00106.25 KFM26283.1 - 3.4e-43 147.4 0.0 4.2e-43 147.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM26283.1 - 7.9e-27 94.3 0.1 9.9e-27 94.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM26283.1 - 2.5e-14 53.6 0.1 3.8e-14 53.0 0.1 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KFM26283.1 - 0.055 12.8 0.0 0.11 11.8 0.0 1.5 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 KFM26283.1 - 0.16 11.8 0.2 0.23 11.3 0.2 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pro_isomerase PF00160.21 KFM26284.1 - 0.0016 18.7 0.0 0.014 15.7 0.0 2.0 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Lactamase_B_2 PF12706.7 KFM26285.1 - 6.6e-13 48.6 0.4 3.3e-11 43.1 0.0 2.9 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KFM26285.1 - 3e-05 24.1 0.2 8.1e-05 22.7 0.1 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily R3H PF01424.22 KFM26286.1 - 1.5e-09 37.7 0.0 2.8e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 R3H domain Sybindin PF04099.12 KFM26287.1 - 1e-23 83.8 0.0 1.1e-23 83.7 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 KFM26287.1 - 1.5e-06 28.4 0.0 1.7e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region PfkB PF00294.24 KFM26288.1 - 1.2e-27 97.1 4.3 4.9e-14 52.3 3.8 2.1 1 1 1 2 2 2 2 pfkB family carbohydrate kinase ABC_tran PF00005.27 KFM26289.1 - 2.3e-24 86.5 0.0 3.6e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KFM26289.1 - 6.1e-05 23.0 0.0 0.0001 22.2 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 KFM26289.1 - 0.00023 21.1 0.0 0.78 9.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KFM26289.1 - 0.0018 17.9 0.2 0.011 15.3 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFM26289.1 - 0.0035 17.7 0.3 0.0076 16.6 0.3 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 KFM26289.1 - 0.011 16.3 0.0 0.017 15.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KFM26289.1 - 0.027 14.8 0.0 0.052 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KFM26289.1 - 0.031 14.0 0.1 0.061 13.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KFM26289.1 - 0.034 13.9 0.1 0.085 12.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.19 KFM26289.1 - 0.052 13.1 0.1 0.082 12.5 0.1 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KFM26289.1 - 0.08 12.9 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.23 KFM26289.1 - 0.091 12.8 0.2 0.17 12.0 0.2 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.6 KFM26289.1 - 0.12 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain BCLP PF12304.8 KFM26289.1 - 0.55 9.7 6.8 0.23 11.0 1.4 2.1 1 1 1 2 2 2 0 Beta-casein like protein NUDIX PF00293.28 KFM26291.1 - 4.8e-16 59.0 0.2 5.7e-16 58.7 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX PF00293.28 KFM26292.1 - 1.5e-19 70.3 0.5 2e-19 69.9 0.5 1.1 1 0 0 1 1 1 1 NUDIX domain DUF5010 PF16402.5 KFM26292.1 - 0.28 10.0 0.0 0.35 9.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5010) DUF563 PF04577.14 KFM26293.1 - 1.4e-15 58.0 0.0 1.7e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF563) HMA PF00403.26 KFM26295.1 - 2.1e-09 37.7 1.5 2.6e-09 37.4 1.5 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain ADK_lid PF05191.14 KFM26295.1 - 0.057 13.4 0.5 0.12 12.4 0.5 1.5 1 1 0 1 1 1 0 Adenylate kinase, active site lid DUF962 PF06127.11 KFM26296.1 - 1.3e-21 76.5 0.3 2.4e-21 75.6 0.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF962) ERM PF00769.19 KFM26298.1 - 0.01 15.7 5.6 0.017 14.9 5.6 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF3584 PF12128.8 KFM26298.1 - 0.026 12.1 2.4 0.033 11.7 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TelA PF05816.11 KFM26298.1 - 0.042 12.9 0.6 0.055 12.5 0.6 1.1 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) Seryl_tRNA_N PF02403.22 KFM26298.1 - 0.33 11.2 5.7 0.11 12.8 2.8 1.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.6 KFM26298.1 - 2.7 7.3 11.6 5.5 6.2 11.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2968 PF11180.8 KFM26298.1 - 3.7 7.1 10.4 0.22 11.2 4.3 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2968) Spc7 PF08317.11 KFM26298.1 - 4.7 6.0 5.6 1.2 7.9 2.3 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein DivIC PF04977.15 KFM26298.1 - 6.5 6.6 9.0 0.71 9.7 0.1 2.7 2 1 1 3 3 3 0 Septum formation initiator PALP PF00291.25 KFM26300.1 - 2.6e-78 263.4 10.6 3.1e-78 263.1 10.6 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 KFM26300.1 - 4.8e-28 96.8 0.0 6.6e-15 54.7 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase K_trans PF02705.16 KFM26301.1 - 2.1e-159 531.5 14.1 3.2e-159 530.9 14.1 1.2 1 0 0 1 1 1 1 K+ potassium transporter MWFE PF15879.5 KFM26301.1 - 0.54 10.5 2.6 31 4.8 0.3 3.4 4 0 0 4 4 4 0 NADH-ubiquinone oxidoreductase MWFE subunit Ank_5 PF13857.6 KFM26302.1 - 1.2e-13 51.0 0.1 1.9e-07 31.2 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Chromo PF00385.24 KFM26302.1 - 6.9e-13 48.3 1.2 9.2e-06 25.5 0.2 3.4 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Ank PF00023.30 KFM26302.1 - 1e-10 41.6 0.3 0.00048 20.4 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KFM26302.1 - 1.9e-09 38.0 0.1 9.2e-09 35.8 0.1 2.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM26302.1 - 5.6e-09 36.4 0.0 1.9e-08 34.7 0.0 1.9 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM26302.1 - 8.4e-08 31.9 0.0 0.0024 18.2 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat DUF1918 PF08940.11 KFM26302.1 - 0.00015 21.3 0.9 0.12 12.0 0.0 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF1918) Tudor_3 PF18115.1 KFM26302.1 - 0.0053 16.6 0.0 13 5.8 0.0 3.3 3 0 0 3 3 3 1 DNA repair protein Crb2 Tudor domain PWWP PF00855.17 KFM26302.1 - 0.027 14.9 0.0 21 5.6 0.0 3.0 2 1 1 3 3 3 0 PWWP domain DUF3564 PF12087.8 KFM26302.1 - 0.38 10.7 2.5 12 5.9 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3564) SE PF08491.10 KFM26303.1 - 3.6e-102 341.1 0.0 4.9e-102 340.7 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 KFM26303.1 - 1.6e-10 40.8 0.2 1.4e-09 37.6 0.2 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KFM26303.1 - 3.3e-09 36.8 2.0 0.00092 18.9 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFM26303.1 - 0.016 14.3 3.2 0.017 14.2 1.5 1.8 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 KFM26303.1 - 0.022 13.5 0.0 0.031 13.0 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_8 PF13450.6 KFM26303.1 - 0.027 14.7 0.6 0.027 14.7 0.6 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFM26303.1 - 0.032 13.4 0.2 0.051 12.8 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KFM26303.1 - 0.1 11.6 0.0 0.23 10.5 0.1 1.4 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KFM26303.1 - 0.12 11.3 3.1 0.055 12.5 0.5 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein Complex1_LYR PF05347.15 KFM26305.1 - 0.0033 17.4 0.0 0.0048 16.9 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) ABC_membrane PF00664.23 KFM26306.1 - 6.5e-35 121.1 7.8 1.3e-34 120.1 7.8 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KFM26306.1 - 2.8e-33 115.3 0.0 4.3e-33 114.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KFM26306.1 - 1.7e-06 27.7 0.2 0.00029 20.3 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KFM26306.1 - 2.4e-05 24.8 0.1 5.9e-05 23.5 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KFM26306.1 - 0.0053 16.5 0.1 0.017 14.8 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KFM26306.1 - 0.013 15.3 0.2 0.052 13.3 0.1 1.9 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KFM26306.1 - 0.025 14.9 0.2 0.13 12.5 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KFM26306.1 - 0.031 13.9 0.5 0.14 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KFM26306.1 - 0.051 13.7 0.0 0.17 12.0 0.0 2.0 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF87 PF01935.17 KFM26306.1 - 0.094 12.8 0.1 0.17 11.9 0.1 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain RsgA_GTPase PF03193.16 KFM26306.1 - 0.097 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_7 PF12775.7 KFM26306.1 - 0.098 12.2 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_15 PF13175.6 KFM26306.1 - 0.1 12.3 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 KFM26306.1 - 0.12 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 KFM26306.1 - 0.12 12.9 0.0 0.2 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KFM26306.1 - 0.13 11.6 0.1 0.25 10.6 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family MoeA_C PF03454.15 KFM26306.1 - 0.15 12.2 0.8 0.72 10.1 0.1 2.6 4 0 0 4 4 3 0 MoeA C-terminal region (domain IV) ADH_N PF08240.12 KFM26307.1 - 3.7e-26 91.2 0.4 6e-26 90.5 0.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFM26307.1 - 1e-15 57.9 1.3 2.2e-15 56.8 1.3 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KFM26307.1 - 1.9e-06 27.5 1.0 4.8e-06 26.2 1.1 1.5 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KFM26307.1 - 0.00033 21.7 0.0 0.0011 20.1 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase zf-CCCH PF00642.24 KFM26308.1 - 1.8e-07 30.9 2.2 1.8e-07 30.9 2.2 3.4 4 0 0 4 4 4 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFM26308.1 - 1.3e-05 25.1 2.7 1.3e-05 25.1 2.7 3.6 4 0 0 4 4 4 1 Zinc finger domain zf-CCCH_4 PF18044.1 KFM26308.1 - 2e-05 24.2 2.1 2e-05 24.2 2.1 3.6 4 0 0 4 4 4 1 CCCH-type zinc finger Ank PF00023.30 KFM26308.1 - 0.0008 19.7 2.9 0.0057 17.1 0.5 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 KFM26308.1 - 0.012 16.2 0.0 0.019 15.5 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) zf-CCCH_2 PF14608.6 KFM26308.1 - 0.1 13.1 14.6 3.3 8.3 2.5 3.9 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger Ank_5 PF13857.6 KFM26308.1 - 0.22 11.9 0.6 7.3 7.0 0.1 2.6 2 1 1 3 3 3 0 Ankyrin repeats (many copies) SQAPI PF16845.5 KFM26309.1 - 5.5e-08 33.0 0.1 6.1e-06 26.5 0.1 2.1 2 0 0 2 2 2 2 Aspartic acid proteinase inhibitor Cystatin PF00031.21 KFM26309.1 - 0.0087 16.3 0.0 0.4 11.0 0.0 2.3 2 1 0 2 2 2 1 Cystatin domain Myb_DNA-binding PF00249.31 KFM26310.1 - 1.5e-36 124.4 15.6 9e-15 54.6 1.0 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFM26310.1 - 2e-36 124.0 8.9 1.4e-15 57.3 0.2 3.2 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KFM26310.1 - 0.00062 19.6 0.1 0.8 9.6 0.0 2.3 1 1 1 2 2 2 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 KFM26310.1 - 0.024 14.8 0.3 0.94 9.7 0.1 2.3 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 DUF664 PF04978.12 KFM26310.1 - 0.066 13.6 1.0 0.41 11.1 0.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF664) Histone PF00125.24 KFM26312.1 - 7.6e-53 178.4 2.5 8.5e-53 178.2 2.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 KFM26312.1 - 0.0001 22.9 1.4 0.00013 22.6 1.4 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 KFM26312.1 - 0.00018 21.8 0.0 0.00027 21.2 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KFM26312.1 - 0.00026 21.0 0.7 0.00035 20.6 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KFM26312.1 - 0.0015 18.8 0.1 0.0029 17.9 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KFM26312.1 - 0.0096 16.0 0.2 0.018 15.1 0.0 1.5 2 0 0 2 2 2 1 Transcription initiation factor IID, 31kD subunit PRAI PF00697.22 KFM26312.1 - 0.17 11.6 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase CENP-T_C PF15511.6 KFM26314.1 - 2e-08 34.3 0.1 2.5e-08 34.0 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KFM26314.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KFM26314.1 - 0.00022 21.3 0.1 0.00031 20.8 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.13 KFM26314.1 - 0.0011 18.9 0.1 0.0017 18.4 0.1 1.2 1 0 0 1 1 1 1 Bromodomain associated CBFD_NFYB_HMF PF00808.23 KFM26314.1 - 0.0013 19.0 0.0 0.0022 18.3 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFM26314.1 - 0.0015 18.9 0.1 0.0017 18.8 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KFM26314.1 - 0.033 14.3 0.0 0.037 14.1 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Myb_DNA-binding PF00249.31 KFM26315.1 - 5.5e-28 96.9 5.3 2.6e-13 49.9 1.4 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFM26315.1 - 5e-22 77.9 3.2 1.5e-14 54.0 1.5 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 KFM26315.1 - 0.0015 18.6 2.4 0.071 13.2 0.2 2.3 2 0 0 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain MADF_DNA_bdg PF10545.9 KFM26315.1 - 0.0018 18.5 4.1 0.36 11.2 1.1 2.3 1 1 1 2 2 2 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_7 PF15963.5 KFM26315.1 - 0.0029 17.5 0.0 0.0089 15.9 0.0 1.7 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 KFM26315.1 - 0.0096 16.3 2.8 2.2 8.7 2.1 2.6 1 1 1 2 2 2 2 Myb/SANT-like DNA-binding domain SLIDE PF09111.10 KFM26315.1 - 0.045 13.8 0.0 4.3 7.4 0.0 2.4 1 1 1 2 2 2 0 SLIDE UBA_4 PF14555.6 KFM26316.1 - 3.4e-14 52.4 0.3 6.9e-14 51.4 0.3 1.6 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_7 PF13899.6 KFM26316.1 - 2.3e-10 40.5 0.0 5.6e-10 39.3 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin-like UBX PF00789.20 KFM26316.1 - 3.4e-06 27.2 0.0 6.2e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 UBX domain UIM PF02809.20 KFM26316.1 - 0.021 14.7 1.0 0.021 14.7 1.0 2.6 2 0 0 2 2 2 0 Ubiquitin interaction motif CUE PF02845.16 KFM26316.1 - 0.11 12.3 0.0 0.29 10.9 0.0 1.7 1 0 0 1 1 1 0 CUE domain Linker_histone PF00538.19 KFM26317.1 - 8.2e-16 58.1 0.1 8.2e-16 58.1 0.1 1.6 2 0 0 2 2 2 1 linker histone H1 and H5 family Ribosomal_60s PF00428.19 KFM26317.1 - 2.1 9.0 9.6 3.1 8.5 9.6 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein CPSase_L_D2 PF02786.17 KFM26318.1 - 3.7e-75 252.0 0.1 5.8e-75 251.4 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KFM26318.1 - 3.3e-41 140.3 0.0 6.3e-41 139.4 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KFM26318.1 - 8.3e-31 106.3 0.0 2.3e-30 104.9 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KFM26318.1 - 8e-14 51.2 0.1 1.9e-13 50.0 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KFM26318.1 - 3.8e-10 39.6 0.0 8.3e-10 38.5 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KFM26318.1 - 5.1e-07 29.4 0.0 8.5e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KFM26318.1 - 0.0004 20.2 0.0 0.00063 19.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RnfC_N PF13375.6 KFM26318.1 - 0.0029 17.5 0.0 0.0079 16.1 0.0 1.7 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain ATP-grasp_5 PF13549.6 KFM26318.1 - 0.011 15.2 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain LAL_C2 PF18603.1 KFM26318.1 - 0.036 14.2 0.3 0.79 9.9 0.0 3.2 3 0 0 3 3 3 0 L-amino acid ligase C-terminal domain 2 GCV_H PF01597.19 KFM26318.1 - 0.048 13.5 0.0 0.13 12.1 0.0 1.7 1 1 1 2 2 2 0 Glycine cleavage H-protein ATP-grasp_3 PF02655.14 KFM26318.1 - 0.049 13.7 0.0 0.076 13.1 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain ECH_1 PF00378.20 KFM26319.1 - 1e-63 215.0 0.0 1.2e-63 214.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFM26319.1 - 1.1e-38 133.6 0.0 2.4e-37 129.2 0.0 1.9 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Abhydrolase_1 PF00561.20 KFM26320.1 - 8.2e-23 81.4 0.2 1.9e-18 67.0 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFM26320.1 - 6.7e-16 58.3 0.1 4e-13 49.2 0.1 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFM26320.1 - 8.6e-14 52.7 13.8 1.9e-13 51.5 13.8 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 KFM26320.1 - 7.5e-06 25.8 0.1 2.5e-05 24.1 0.1 1.8 2 0 0 2 2 2 1 Putative esterase Abhydrolase_3 PF07859.13 KFM26320.1 - 0.0012 18.8 0.1 0.003 17.5 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold LIDHydrolase PF10230.9 KFM26320.1 - 0.008 15.8 0.0 0.023 14.2 0.0 1.6 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase Ndr PF03096.14 KFM26320.1 - 0.0085 14.8 0.0 0.012 14.3 0.0 1.2 1 0 0 1 1 1 1 Ndr family Ser_hydrolase PF06821.13 KFM26320.1 - 0.019 14.8 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase Peptidase_S9 PF00326.21 KFM26320.1 - 0.019 14.4 0.0 0.14 11.6 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family Thioesterase PF00975.20 KFM26320.1 - 0.11 12.5 0.4 0.37 10.9 0.4 1.7 2 0 0 2 2 2 0 Thioesterase domain PGAP1 PF07819.13 KFM26320.1 - 0.17 11.6 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Galactosyl_T PF01762.21 KFM26321.1 - 2.4e-18 66.7 0.0 4.1e-16 59.4 0.0 2.1 2 0 0 2 2 2 2 Galactosyltransferase DUF737 PF05300.11 KFM26322.1 - 0.0026 18.1 0.2 0.0031 17.9 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF737) SusD_RagB PF07980.11 KFM26322.1 - 0.11 12.0 0.3 0.14 11.8 0.3 1.2 1 0 0 1 1 1 0 SusD family YabA PF06156.13 KFM26322.1 - 0.14 12.8 7.8 0.22 12.2 5.1 2.1 1 1 1 2 2 2 0 Initiation control protein YabA PRKG1_interact PF15898.5 KFM26322.1 - 0.72 10.8 10.3 1.6 9.6 10.3 1.6 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain CRISPR_Cas2 PF09827.9 KFM26322.1 - 1.5 9.1 3.9 7 6.9 0.1 2.3 1 1 1 2 2 2 0 CRISPR associated protein Cas2 RapA_C PF12137.8 KFM26322.1 - 1.7 7.5 8.8 1.8 7.5 3.2 1.8 1 1 1 2 2 2 0 RNA polymerase recycling family C-terminal ZapB PF06005.12 KFM26322.1 - 2 8.9 11.2 1.1 9.7 7.9 2.0 1 1 1 2 2 2 0 Cell division protein ZapB DivIC PF04977.15 KFM26322.1 - 6.9 6.5 8.1 5.4 6.9 5.2 2.2 1 1 2 3 3 3 0 Septum formation initiator Proteasome PF00227.26 KFM26323.1 - 4e-40 137.3 0.0 5.6e-40 136.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit MoCF_biosynth PF00994.24 KFM26323.1 - 1.2e-29 102.9 0.0 2.1e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain DUF4381 PF14316.6 KFM26324.1 - 0.00071 19.8 1.3 0.00071 19.8 1.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4381) LRR_8 PF13855.6 KFM26324.1 - 0.0013 18.5 0.0 0.0032 17.2 0.0 1.6 1 0 0 1 1 1 1 Leucine rich repeat Kinase-like PF14531.6 KFM26324.1 - 0.0042 16.5 0.0 0.0069 15.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 KFM26324.1 - 0.016 14.6 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain LRRNT_2 PF08263.12 KFM26324.1 - 0.026 14.8 1.2 0.056 13.8 1.2 1.6 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 KFM26324.1 - 0.058 13.5 0.1 1.7 8.9 0.0 3.0 3 0 0 3 3 3 0 Leucine Rich repeat LapA_dom PF06305.11 KFM26324.1 - 0.18 11.6 2.5 0.43 10.4 2.5 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain CcmD PF04995.14 KFM26324.1 - 0.32 11.1 7.2 0.91 9.7 7.2 1.8 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Patatin PF01734.22 KFM26326.1 - 0.00011 22.4 2.4 0.0013 19.0 2.4 2.2 1 1 0 1 1 1 1 Patatin-like phospholipase Ribosomal_L6 PF00347.23 KFM26327.1 - 9.4e-26 90.3 2.0 9.7e-13 48.6 0.4 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 MS_channel PF00924.18 KFM26328.1 - 1.1e-11 44.6 0.0 2.1e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 KFM26328.1 - 0.052 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 KFM26328.1 - 0.15 12.0 0.0 0.44 10.6 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain ThiS PF02597.20 KFM26329.1 - 3.6e-16 59.6 0.0 4e-16 59.4 0.0 1.0 1 0 0 1 1 1 1 ThiS family Lambda_tail_I PF06805.12 KFM26329.1 - 0.0097 16.2 0.0 0.012 15.9 0.0 1.2 1 0 0 1 1 1 1 Bacteriophage lambda tail assembly protein I Glyoxalase PF00903.25 KFM26330.1 - 4e-06 27.1 0.0 8.8e-06 25.9 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 KFM26330.1 - 0.0012 18.8 0.0 0.002 18.0 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain Cons_hypoth95 PF03602.15 KFM26331.1 - 3.1e-30 105.2 0.0 3.4e-30 105.0 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MethyltransfD12 PF02086.15 KFM26331.1 - 0.033 13.9 0.1 0.06 13.0 0.0 1.4 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase Phage_lysis PF03245.13 KFM26332.1 - 0.019 15.1 1.7 0.022 14.9 1.7 1.1 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein SOUL PF04832.12 KFM26333.1 - 9.4e-31 107.2 0.0 1.1e-30 107.0 0.0 1.1 1 0 0 1 1 1 1 SOUL heme-binding protein Metallophos PF00149.28 KFM26334.1 - 7.1e-11 43.0 0.0 2.4e-10 41.3 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Sugar_tr PF00083.24 KFM26335.1 - 2.2e-35 122.4 18.9 8.6e-28 97.4 10.3 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KFM26335.1 - 9.7e-27 93.8 52.2 6.9e-16 58.1 31.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 KFM26335.1 - 0.0078 15.2 0.1 0.013 14.4 0.1 1.3 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM Rapsyn_N PF10579.9 KFM26336.1 - 0.04 14.0 0.0 0.073 13.2 0.0 1.4 1 0 0 1 1 1 0 Rapsyn N-terminal myristoylation and linker region Glyco_hydro_63 PF03200.16 KFM26337.1 - 2.1e-142 475.4 0.0 2.8e-142 475.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 KFM26337.1 - 5.1e-41 141.2 0.0 8.4e-41 140.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain Lyase_1 PF00206.20 KFM26337.1 - 6e-36 124.4 0.0 8.6e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 Lyase Thymidylate_kin PF02223.17 KFM26338.1 - 1.4e-28 99.8 0.0 1.6e-28 99.6 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase ASL_C PF08328.11 KFM26339.1 - 5.3e-45 152.2 0.0 7e-45 151.8 0.0 1.2 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminal Lyase_1 PF00206.20 KFM26339.1 - 3.9e-14 52.8 0.0 6e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Lyase Glyco_transf_21 PF13506.6 KFM26339.1 - 0.077 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 21 RRM_1 PF00076.22 KFM26340.1 - 6.8e-12 45.0 0.0 1.2e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFM26340.1 - 0.0015 18.6 0.0 0.0024 17.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif Nup35_RRM_2 PF14605.6 KFM26340.1 - 0.017 15.1 0.0 0.032 14.2 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Aldedh PF00171.22 KFM26341.1 - 0.038 12.5 0.1 0.061 11.8 0.1 1.3 1 0 0 1 1 1 0 Aldehyde dehydrogenase family Aldedh PF00171.22 KFM26342.1 - 3.4e-06 25.9 0.3 0.00072 18.2 0.1 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family ChaC PF04752.12 KFM26343.1 - 3.2e-49 167.4 0.0 3.8e-49 167.2 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein OKR_DC_1 PF01276.20 KFM26345.1 - 1.9e-13 50.0 0.0 7.3e-12 44.7 0.0 2.5 1 1 2 3 3 3 1 Orn/Lys/Arg decarboxylase, major domain OKR_DC_1_C PF03711.15 KFM26345.1 - 2.7e-05 24.5 0.3 4.6e-05 23.7 0.3 1.3 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, C-terminal domain Cys_Met_Meta_PP PF01053.20 KFM26345.1 - 0.00041 19.0 0.0 0.0005 18.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KFM26345.1 - 0.031 13.4 0.0 0.046 12.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II SHMT PF00464.19 KFM26345.1 - 0.034 12.7 0.2 0.045 12.4 0.2 1.1 1 0 0 1 1 1 0 Serine hydroxymethyltransferase Aminotran_5 PF00266.19 KFM26345.1 - 0.041 12.8 0.1 0.056 12.4 0.1 1.1 1 0 0 1 1 1 0 Aminotransferase class-V Beta_elim_lyase PF01212.21 KFM26345.1 - 0.077 12.3 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase UQ_con PF00179.26 KFM26346.1 - 2.8e-23 82.1 0.0 3.4e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme CLP_protease PF00574.23 KFM26347.1 - 4.5e-76 254.8 0.1 5.4e-76 254.5 0.1 1.0 1 0 0 1 1 1 1 Clp protease Fibrillarin PF01269.17 KFM26348.1 - 2.3e-69 233.0 0.0 1.7e-41 141.9 0.0 2.0 1 1 1 2 2 2 2 Fibrillarin PCMT PF01135.19 KFM26348.1 - 0.051 13.3 0.0 0.099 12.4 0.0 1.5 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Bax1-I PF01027.20 KFM26349.1 - 4e-42 144.4 25.3 4.6e-42 144.2 25.3 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 PAP_central PF04928.17 KFM26349.1 - 0.19 10.7 0.4 0.29 10.1 0.4 1.2 1 0 0 1 1 1 0 Poly(A) polymerase central domain CPP1-like PF11833.8 KFM26349.1 - 8.6 6.0 10.3 17 5.0 10.3 1.4 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like HMG_box PF00505.19 KFM26350.1 - 2.2e-10 40.8 0.0 4e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFM26350.1 - 2e-05 25.1 0.0 4.4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.12 KFM26350.1 - 2.5e-05 24.1 0.0 4.6e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 CHDNT (NUC034) domain Rotamase PF00639.21 KFM26352.1 - 4.3e-22 78.9 0.0 4.9e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 KFM26352.1 - 5.4e-20 72.1 0.0 5.9e-20 72.0 0.0 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 KFM26352.1 - 6.2e-05 23.8 0.0 7.6e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain PLATZ PF04640.14 KFM26353.1 - 2.3e-17 63.4 2.6 3.5e-17 62.8 2.6 1.3 1 0 0 1 1 1 1 PLATZ transcription factor AAA_2 PF07724.14 KFM26355.1 - 1.8e-43 148.6 0.1 1.8e-35 122.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 KFM26355.1 - 3.4e-14 53.4 0.2 1.9e-06 28.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KFM26355.1 - 1.9e-09 37.5 3.8 1.3e-08 34.8 0.2 3.0 3 0 0 3 3 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KFM26355.1 - 1.7e-07 31.3 0.1 2.8e-05 24.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KFM26355.1 - 2.6e-06 27.3 0.5 0.00016 21.4 0.0 2.5 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KFM26355.1 - 9.5e-06 26.1 1.0 0.00017 22.0 0.1 2.7 2 2 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KFM26355.1 - 4.1e-05 23.8 0.1 0.00013 22.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain MCM PF00493.23 KFM26355.1 - 6.3e-05 22.2 0.2 0.0074 15.4 0.0 2.5 2 1 0 2 2 2 1 MCM P-loop domain AAA_28 PF13521.6 KFM26355.1 - 7.5e-05 23.0 0.2 0.00027 21.2 0.0 2.0 3 0 0 3 3 1 1 AAA domain AAA_22 PF13401.6 KFM26355.1 - 7.7e-05 23.0 0.0 0.00088 19.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KFM26355.1 - 0.00021 20.6 0.0 0.00044 19.6 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.21 KFM26355.1 - 0.00034 20.1 0.0 0.0023 17.4 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KFM26355.1 - 0.002 17.9 0.0 0.053 13.2 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.6 KFM26355.1 - 0.0026 18.3 0.0 0.0055 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 KFM26355.1 - 0.018 14.2 0.0 0.04 13.1 0.0 1.6 1 0 0 1 1 1 0 TIP49 P-loop domain ABC_tran PF00005.27 KFM26355.1 - 0.019 15.5 0.0 0.039 14.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 KFM26355.1 - 0.028 14.4 0.0 6.2 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KFM26355.1 - 0.033 13.9 0.0 0.069 12.9 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 KFM26355.1 - 0.04 13.3 0.1 0.13 11.6 0.0 2.0 2 0 0 2 2 1 0 Bacterial TniB protein AAA_7 PF12775.7 KFM26355.1 - 0.054 13.0 0.0 0.16 11.5 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 KFM26355.1 - 0.058 13.0 0.9 3 7.4 0.1 2.8 3 0 0 3 3 3 0 AAA domain SKI PF01202.22 KFM26355.1 - 0.06 13.5 0.1 1.3 9.1 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase Rad17 PF03215.15 KFM26355.1 - 0.069 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain NACHT PF05729.12 KFM26355.1 - 0.082 12.8 0.0 1.3 8.9 0.0 2.5 2 1 0 2 2 2 0 NACHT domain ATP-synt_ab PF00006.25 KFM26355.1 - 0.084 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF826 PF05696.11 KFM26355.1 - 0.09 12.9 0.1 0.45 10.6 0.1 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF826) IstB_IS21 PF01695.17 KFM26355.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein TsaE PF02367.17 KFM26355.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KFM26355.1 - 0.19 11.4 1.0 0.93 9.2 0.2 2.3 2 1 0 2 2 2 0 AAA domain RsfS PF02410.15 KFM26356.1 - 2.4e-13 50.3 0.0 3.3e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation Methyltransf_11 PF08241.12 KFM26357.1 - 5e-07 30.3 0.0 1.1e-06 29.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM26357.1 - 1.2e-06 29.1 0.1 3.4e-06 27.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain GTPase_binding PF09027.10 KFM26357.1 - 0.025 14.6 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 GTPase binding Methyltransf_31 PF13847.6 KFM26357.1 - 0.044 13.6 0.1 0.073 12.9 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain NIF PF03031.18 KFM26358.1 - 6.5e-48 162.4 0.0 8.4e-48 162.1 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase WD40 PF00400.32 KFM26359.1 - 1.3e-43 146.1 14.2 7.2e-06 26.7 0.0 11.3 12 0 0 12 12 12 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM26359.1 - 9e-27 93.2 0.0 0.02 15.2 0.0 9.5 4 2 6 10 10 10 7 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 KFM26359.1 - 1.9e-17 63.5 0.0 3.3e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 KFM26359.1 - 6.8e-08 31.8 0.0 0.023 13.7 0.0 5.2 3 2 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KFM26359.1 - 0.00016 21.6 0.0 0.0039 17.1 0.0 3.1 4 1 1 5 5 5 1 Eukaryotic translation initiation factor eIF2A DUF1513 PF07433.11 KFM26359.1 - 0.046 12.8 0.6 1.1 8.2 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1513) Nup160 PF11715.8 KFM26359.1 - 0.19 10.3 0.1 0.92 8.1 0.0 2.2 1 1 0 2 2 2 0 Nucleoporin Nup120/160 BNR_4 PF15892.5 KFM26359.1 - 0.21 10.9 0.0 0.42 9.9 0.0 1.4 1 0 0 1 1 1 0 BNR repeat-containing family member Proteasome_A_N PF10584.9 KFM26359.1 - 2.5 7.9 6.4 99 2.8 0.1 4.8 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature TPT PF03151.16 KFM26360.1 - 3.5e-16 59.4 1.1 4.4e-16 59.1 1.1 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family Dynamin_N PF00350.23 KFM26362.1 - 9.1e-49 165.7 0.0 1.6e-48 164.9 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KFM26362.1 - 2.5e-48 164.7 0.0 5e-48 163.8 0.0 1.4 2 0 0 2 2 2 1 Dynamin central region GED PF02212.18 KFM26362.1 - 3.2e-16 59.2 1.5 7.3e-16 58.1 1.5 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain Redoxin PF08534.10 KFM26362.1 - 2.9e-07 30.3 0.0 5.1e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Redoxin MMR_HSR1 PF01926.23 KFM26362.1 - 3.8e-05 23.8 0.0 0.00012 22.2 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 KFM26362.1 - 0.0047 17.2 0.2 0.018 15.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain Transcrip_act PF04949.13 KFM26362.1 - 0.055 13.3 1.3 40 4.1 0.0 3.3 2 1 0 2 2 2 0 Transcriptional activator Roc PF08477.13 KFM26362.1 - 0.13 12.4 0.1 1.6 8.9 0.0 2.5 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase DNAPolymera_Pol PF11590.8 KFM26362.1 - 1.9 8.4 6.4 4.3 7.3 0.3 3.1 3 0 0 3 3 3 0 DNA polymerase catalytic subunit Pol PH PF00169.29 KFM26363.1 - 2e-06 28.2 0.0 3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 PH domain SNCAIP_SNCA_bd PF16700.5 KFM26363.1 - 0.057 13.1 1.6 0.5 10.1 0.5 2.3 2 0 0 2 2 2 0 Synphilin-1 alpha-Synuclein-binding domain Dynamin_M PF01031.20 KFM26363.1 - 0.24 10.6 0.0 0.37 10.0 0.0 1.2 1 0 0 1 1 1 0 Dynamin central region MafB19-deam PF14437.6 KFM26364.1 - 1.1e-23 83.5 0.0 1.7e-23 82.9 0.0 1.3 1 1 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 KFM26364.1 - 3.6e-20 71.7 0.2 5.1e-20 71.2 0.2 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.6 KFM26364.1 - 0.0015 18.6 4.4 0.013 15.5 4.4 2.0 1 1 0 1 1 1 1 Bd3614-like deaminase SNAD4 PF18750.1 KFM26364.1 - 0.0056 16.8 0.0 0.011 15.8 0.0 1.5 2 0 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 KFM26364.1 - 0.086 12.9 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 APOBEC2 Inv-AAD PF18785.1 KFM26364.1 - 0.17 11.7 0.3 0.7 9.8 0.3 1.8 1 1 0 1 1 1 0 Invertebrate-AID/APOBEC-deaminase NAD1 PF18778.1 KFM26364.1 - 0.26 11.4 0.0 0.4 10.8 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 DENN PF02141.21 KFM26365.1 - 1.1e-31 110.2 0.0 1.6e-27 96.6 0.1 2.3 2 0 0 2 2 2 2 DENN (AEX-3) domain uDENN PF03456.18 KFM26365.1 - 8.5e-08 32.8 0.8 2.2e-07 31.5 0.0 2.1 3 0 0 3 3 3 1 uDENN domain dDENN PF03455.19 KFM26365.1 - 9.2e-07 28.8 0.2 2.9e-06 27.1 0.1 2.0 2 0 0 2 2 2 1 dDENN domain SPA PF08616.10 KFM26365.1 - 0.071 13.1 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Stabilization of polarity axis DUF393 PF04134.12 KFM26366.1 - 1.5e-15 58.5 0.1 1.7e-15 58.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF393 Prefoldin_2 PF01920.20 KFM26367.1 - 0.00015 21.7 17.2 0.051 13.5 0.0 5.7 4 2 1 6 6 6 2 Prefoldin subunit Leu_zip PF15294.6 KFM26367.1 - 0.00075 19.1 24.7 0.055 13.0 7.0 3.3 1 1 0 3 3 3 2 Leucine zipper DUF1664 PF07889.12 KFM26367.1 - 0.39 10.8 10.3 0.35 10.9 0.8 3.8 3 2 0 3 3 3 0 Protein of unknown function (DUF1664) HIP1_clath_bdg PF16515.5 KFM26367.1 - 0.58 10.8 45.5 0.082 13.5 7.1 5.4 1 1 3 5 5 5 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Baculo_PEP_C PF04513.12 KFM26367.1 - 1 9.4 11.2 0.46 10.5 0.5 3.7 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus GAS PF13851.6 KFM26367.1 - 1 8.6 34.2 1.6 8.0 7.0 3.7 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding HMMR_N PF15905.5 KFM26367.1 - 1.4 8.4 24.7 0.31 10.5 3.1 3.3 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor N-terminal Filament PF00038.21 KFM26367.1 - 2.3 7.7 50.4 0.98 8.9 22.3 4.3 1 1 3 4 4 4 0 Intermediate filament protein YabA PF06156.13 KFM26367.1 - 2.3 8.9 13.2 60 4.3 1.3 5.2 2 1 2 5 5 5 0 Initiation control protein YabA GIT_CC PF16559.5 KFM26367.1 - 2.3 8.1 6.5 4.2 7.3 0.3 3.3 3 1 1 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor Snapin_Pallidin PF14712.6 KFM26367.1 - 2.9 8.4 10.9 2.2 8.8 0.4 3.7 4 0 0 4 4 3 0 Snapin/Pallidin LSM PF01423.22 KFM26368.1 - 9.1e-15 54.1 0.1 1.3e-14 53.6 0.1 1.2 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.7 KFM26368.1 - 0.015 15.3 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 Scd6-like Sm domain SM-ATX PF14438.6 KFM26368.1 - 0.11 12.7 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain CK_II_beta PF01214.18 KFM26370.1 - 2.8e-74 248.9 0.0 3.3e-74 248.6 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Kinocilin PF15033.6 KFM26370.1 - 0.018 14.7 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Kinocilin protein Nucleoporin2 PF04096.14 KFM26371.1 - 4.6e-35 120.9 0.0 6.6e-35 120.4 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin autopeptidase FBPase PF00316.20 KFM26372.1 - 6.5e-31 107.3 0.0 9e-31 106.8 0.0 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain SPC25 PF06703.11 KFM26373.1 - 3.8e-24 85.3 0.0 4.4e-24 85.1 0.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF4118 PF13493.6 KFM26373.1 - 0.44 10.3 4.9 0.8 9.5 4.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4118) Kazal_1 PF00050.21 KFM26374.1 - 1.9e-27 95.0 28.4 1.7e-07 31.2 1.9 4.4 1 1 3 4 4 4 4 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 KFM26374.1 - 7.9e-13 48.3 46.6 0.00046 20.2 4.7 5.5 3 2 2 5 5 5 4 Kazal-type serine protease inhibitor domain Mu-like_Com PF10122.9 KFM26374.1 - 0.0079 15.6 7.9 3.9 7.0 0.0 3.8 2 1 1 3 3 3 3 Mu-like prophage protein Com Ntox44 PF15607.6 KFM26374.1 - 0.027 14.8 1.9 18 5.7 0.0 3.1 3 0 0 3 3 3 0 Bacterial toxin 44 UPF0086 PF01868.16 KFM26375.1 - 2.2e-08 33.9 0.0 2.9e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function UPF0086 GATA PF00320.27 KFM26376.1 - 0.041 13.5 0.1 0.079 12.6 0.1 1.4 1 0 0 1 1 1 0 GATA zinc finger Citrate_bind PF16114.5 KFM26377.1 - 2.9e-74 248.4 0.0 3.7e-74 248.0 0.0 1.1 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 KFM26377.1 - 3.5e-05 23.5 0.0 0.28 10.7 0.0 2.4 1 1 1 2 2 2 2 ATP-grasp domain RETICULATA-like PF11891.8 KFM26378.1 - 2.9e-05 24.0 0.1 4.3e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 Protein RETICULATA-related SLAIN PF15301.6 KFM26378.1 - 0.14 11.4 1.7 0.16 11.2 1.7 1.0 1 0 0 1 1 1 0 SLAIN motif-containing family Glyco_transf_92 PF01697.27 KFM26379.1 - 1.6e-08 34.5 0.0 2.6e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 KFM26379.1 - 1.9e-07 31.5 0.1 4.7e-07 30.2 0.1 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 2 DCP2 PF05026.13 KFM26381.1 - 3.6e-26 91.3 0.0 5.6e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 KFM26381.1 - 6.7e-15 55.3 0.0 1.3e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DUF3228 PF11539.8 KFM26382.1 - 6.9e-78 260.6 0.0 7.8e-78 260.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3228) Mur_ligase_M PF08245.12 KFM26385.1 - 4e-21 75.9 0.0 6e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase PF01225.25 KFM26385.1 - 4.4e-06 26.9 1.1 1e-05 25.8 0.1 2.1 2 0 0 2 2 2 1 Mur ligase family, catalytic domain NCBP3 PF10309.9 KFM26386.1 - 1.6e-16 59.9 0.0 3.4e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 Tho1_MOS11_C PF18592.1 KFM26386.1 - 0.0001 22.0 4.5 0.41 10.5 0.2 3.5 3 0 0 3 3 3 2 Tho1/MOS11 C-terminal domain RNA_bind PF08675.11 KFM26386.1 - 0.00077 19.4 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 RNA binding domain Nup35_RRM_2 PF14605.6 KFM26386.1 - 0.0029 17.6 0.0 0.0047 16.9 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif PXA PF02194.15 KFM26387.1 - 4.8e-23 82.1 0.0 7.8e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 KFM26387.1 - 1e-18 67.9 0.0 2.1e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 Sorting nexin C terminal tRNA-synt_2b PF00587.25 KFM26388.1 - 4.5e-27 95.2 0.0 1.1e-26 93.9 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KFM26388.1 - 1.1e-14 54.5 0.0 1.8e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain MSP1b PF03429.13 KFM26388.1 - 0.34 9.0 1.6 0.48 8.5 1.6 1.1 1 0 0 1 1 1 0 Major surface protein 1B Aminotran_1_2 PF00155.21 KFM26389.1 - 8.3e-69 232.5 0.0 8.5e-39 133.7 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class I and II Aminotran_MocR PF12897.7 KFM26389.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase PsbX PF06596.11 KFM26390.1 - 1.7e-13 50.3 0.5 3.2e-13 49.4 0.5 1.5 1 0 0 1 1 1 1 Photosystem II reaction centre X protein (PsbX) Carboxyl_trans PF01039.22 KFM26391.1 - 3.1e-126 421.9 0.0 2.1e-71 241.1 0.2 2.2 1 1 1 2 2 2 2 Carboxyl transferase domain CPSase_L_D2 PF02786.17 KFM26391.1 - 4.6e-43 147.2 0.0 7.6e-43 146.5 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 KFM26391.1 - 2.3e-22 79.2 0.0 7.1e-22 77.6 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 KFM26391.1 - 4.4e-14 53.0 0.0 9.8e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain ATP-grasp PF02222.22 KFM26391.1 - 4.2e-06 26.5 0.0 1e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KFM26391.1 - 0.0002 21.4 0.0 0.00036 20.6 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain LAL_C2 PF18603.1 KFM26391.1 - 0.002 18.3 3.3 0.031 14.4 0.0 4.0 4 0 0 4 4 4 1 L-amino acid ligase C-terminal domain 2 dCMP_cyt_deam_2 PF08211.12 KFM26392.1 - 2.5e-34 118.4 0.1 5.9e-33 113.9 0.0 2.2 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_1 PF00383.23 KFM26392.1 - 1.9e-11 43.7 0.1 4.1e-11 42.7 0.1 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region OTT_1508_deam PF14441.6 KFM26392.1 - 0.00012 22.0 0.0 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 OTT_1508-like deaminase Ins_P5_2-kin PF06090.12 KFM26393.1 - 5.3e-56 190.4 0.0 8.4e-56 189.8 0.0 1.3 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase ADH_N PF08240.12 KFM26394.1 - 3.8e-19 68.6 0.2 8.6e-19 67.4 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFM26394.1 - 6.4e-11 42.4 0.1 9e-06 25.7 0.0 2.3 2 0 0 2 2 2 2 Zinc-binding dehydrogenase HI0933_like PF03486.14 KFM26394.1 - 0.087 11.5 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Glu_dehyd_C PF16912.5 KFM26394.1 - 0.13 11.7 0.1 1.9 7.9 0.0 2.5 1 1 1 2 2 2 0 Glucose dehydrogenase C-terminus ELFV_dehydrog PF00208.21 KFM26394.1 - 0.15 11.8 0.1 0.23 11.1 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Sec3_C PF09763.9 KFM26395.1 - 1.5e-24 86.5 0.0 2.9e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 Exocyst complex component Sec3 Vps52 PF04129.12 KFM26395.1 - 0.14 10.9 0.1 0.18 10.5 0.1 1.1 1 0 0 1 1 1 0 Vps52 / Sac2 family DUF707 PF05212.12 KFM26396.1 - 0.00023 20.5 0.0 0.013 14.8 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF707) Glyco_transf_64 PF09258.10 KFM26396.1 - 0.0037 16.6 0.0 0.0058 16.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Tmemb_55A PF09788.9 KFM26396.1 - 0.081 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 55A DUF707 PF05212.12 KFM26397.1 - 0.0019 17.5 0.0 0.0021 17.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF707) CdiI_N PF18228.1 KFM26397.1 - 0.043 13.7 0.0 0.067 13.0 0.0 1.3 1 0 0 1 1 1 0 CdiI N-terminal domain DUF707 PF05212.12 KFM26398.1 - 0.056 12.7 0.1 0.17 11.1 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF707) Retro_M PF02813.14 KFM26398.1 - 0.099 13.0 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Retroviral M domain Peptidase_S10 PF00450.22 KFM26399.1 - 5.6e-118 395.0 0.0 6.4e-118 394.8 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Nudix_N_2 PF14803.6 KFM26400.1 - 4.7e-12 45.6 1.3 8e-12 44.9 1.3 1.4 1 0 0 1 1 1 1 Nudix N-terminal NUDIX PF00293.28 KFM26400.1 - 1e-11 45.0 0.1 1.6e-11 44.4 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.11 KFM26400.1 - 0.22 11.2 6.5 3 7.6 6.5 2.2 1 1 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain DEAD PF00270.29 KFM26401.1 - 2.1e-49 167.7 0.0 7.8e-49 165.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM26401.1 - 3.6e-09 36.9 0.0 7.6e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM26401.1 - 0.00019 21.5 0.0 0.00042 20.3 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Cwf_Cwc_15 PF04889.12 KFM26401.1 - 3 7.5 6.5 8 6.1 0.5 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DEAD PF00270.29 KFM26402.1 - 1.6e-30 106.2 0.0 6.1e-30 104.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM26402.1 - 1.7e-27 96.0 0.0 3.4e-27 95.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CdAMP_rec PF06153.11 KFM26402.1 - 0.11 12.7 0.0 0.34 11.1 0.0 1.8 2 0 0 2 2 2 0 Cyclic-di-AMP receptor GHMP_kinases_C PF08544.13 KFM26402.1 - 0.19 12.1 1.9 0.96 9.9 0.6 2.7 2 1 1 3 3 3 0 GHMP kinases C terminal bZIP_1 PF00170.21 KFM26403.1 - 9.1e-10 38.5 11.9 1.7e-09 37.6 11.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFM26403.1 - 4.5e-08 33.0 11.7 8.5e-08 32.2 11.7 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFM26403.1 - 0.002 18.6 3.9 0.002 18.6 3.9 1.8 3 0 0 3 3 3 1 bZIP Maf transcription factor SpoIIE PF07228.12 KFM26404.1 - 1.2e-10 41.7 0.1 2.4e-10 40.6 0.1 1.6 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 KFM26404.1 - 0.048 13.3 0.0 0.13 11.9 0.0 1.6 2 0 0 2 2 2 0 Protein phosphatase 2C CLZ PF16526.5 KFM26404.1 - 0.21 12.0 0.0 0.43 11.0 0.0 1.5 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Mitoc_mL59 PF18126.1 KFM26405.1 - 0.076 13.3 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein mL59 acVLRF1 PF18859.1 KFM26406.1 - 0.016 15.5 0.1 0.017 15.4 0.1 1.1 1 0 0 1 1 1 0 Actinobacteria/chloroflexi VLRF1 release factor Kelch_3 PF13415.6 KFM26407.1 - 0.79 10.1 6.1 0.98 9.8 0.4 2.7 3 0 0 3 3 3 0 Galactose oxidase, central domain WD40 PF00400.32 KFM26408.1 - 2.8e-10 40.6 6.5 0.0048 17.7 0.2 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM26408.1 - 8.7e-06 26.0 0.2 0.028 14.7 0.1 3.0 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFM26408.1 - 0.0036 16.0 0.1 0.04 12.6 0.1 2.1 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Myb_DNA-binding PF00249.31 KFM26409.1 - 1.4e-06 28.4 0.0 2e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Ribosomal_S20p PF01649.18 KFM26410.1 - 1.4e-20 73.7 8.9 2.2e-20 73.1 8.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S20 DUF3584 PF12128.8 KFM26410.1 - 0.035 11.6 1.7 0.041 11.4 1.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PTA_PTB PF01515.19 KFM26411.1 - 6.9e-98 327.9 3.1 1e-97 327.3 3.1 1.2 1 0 0 1 1 1 1 Phosphate acetyl/butaryl transferase DRTGG PF07085.12 KFM26411.1 - 1e-06 28.5 0.0 2.8e-06 27.0 0.0 1.9 1 0 0 1 1 1 1 DRTGG domain TraI PF07057.11 KFM26411.1 - 0.19 11.8 1.3 0.3 11.2 0.1 2.0 2 0 0 2 2 2 0 DNA helicase TraI Acetate_kinase PF00871.17 KFM26412.1 - 4.8e-131 437.1 0.0 5.5e-131 436.9 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family Bep_C_terminal PF17841.1 KFM26413.1 - 0.024 14.9 0.1 0.03 14.5 0.1 1.3 1 0 0 1 1 1 0 BID domain of Bartonella effector protein (Bep) Vps23_core PF09454.10 KFM26413.1 - 0.081 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Vps23 core domain DUF760 PF05542.11 KFM26414.1 - 3e-18 66.0 0.1 6.1e-18 65.0 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF760) WD40 PF00400.32 KFM26414.1 - 9.7e-08 32.6 2.1 0.83 10.6 0.1 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat PRA-PH PF01503.17 KFM26414.1 - 0.019 15.4 0.0 0.054 13.9 0.0 1.8 1 0 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase COX_ARM PF06481.14 KFM26414.1 - 0.11 12.4 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 COX Aromatic Rich Motif PTH2 PF01981.16 KFM26416.1 - 2.9e-42 143.7 0.2 3.5e-42 143.4 0.2 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DHHC PF01529.20 KFM26417.1 - 3.2e-23 82.3 0.6 4.4e-23 81.9 0.6 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase BRO1 PF03097.18 KFM26418.1 - 3e-96 322.6 1.9 3e-96 322.6 1.9 1.8 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KFM26418.1 - 1.4e-59 201.8 1.8 1.4e-59 201.8 1.8 2.2 3 0 0 3 3 3 1 ALIX V-shaped domain binding to HIV Surfac_D-trimer PF09006.11 KFM26418.1 - 0.086 12.7 0.4 0.39 10.6 0.1 2.3 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation DUF2383 PF09537.10 KFM26418.1 - 5.8 7.3 8.1 1.4 9.3 0.2 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF2383) CREPT PF16566.5 KFM26418.1 - 8 6.6 8.7 2 8.6 0.0 3.6 4 0 0 4 4 4 0 Cell-cycle alteration and expression-elevated protein in tumour OTCace PF00185.24 KFM26419.1 - 3.5e-56 189.6 0.1 2e-55 187.2 0.1 1.9 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 KFM26419.1 - 1.6e-44 151.5 0.0 2.2e-44 151.1 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain cEGF PF12662.7 KFM26419.1 - 0.009 15.9 0.9 0.041 13.8 0.3 2.2 2 0 0 2 2 2 1 Complement Clr-like EGF-like Glyco_hydro_101 PF12905.7 KFM26419.1 - 0.028 13.8 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 Endo-alpha-N-acetylgalactosaminidase TPP_enzyme_N PF02776.18 KFM26420.1 - 9.2e-33 113.3 1.1 9.2e-33 113.3 1.1 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KFM26420.1 - 1.4e-23 83.3 0.4 1.4e-22 80.2 0.0 2.7 2 1 1 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain G_glu_transpept PF01019.21 KFM26421.1 - 5.3e-57 193.7 0.1 3.9e-46 157.9 0.0 2.1 1 1 1 2 2 2 2 Gamma-glutamyltranspeptidase DUF3357 PF11837.8 KFM26421.1 - 0.11 12.9 0.1 0.24 11.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) G_glu_transpept PF01019.21 KFM26422.1 - 1.3e-62 212.2 0.0 1.6e-62 212.0 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase RHD3 PF05879.12 KFM26423.1 - 1.1e-112 377.6 0.0 1.2e-112 377.4 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.23 KFM26423.1 - 2.6e-05 24.3 0.0 3.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KFM26423.1 - 4.4e-05 23.6 0.1 7.1e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Dynamin family GBP PF02263.19 KFM26423.1 - 0.00011 21.6 0.0 0.00016 21.0 0.0 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain ABC_tran PF00005.27 KFM26423.1 - 0.001 19.6 0.0 0.0038 17.7 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 KFM26423.1 - 0.0068 16.1 0.1 0.015 15.0 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Septin PF00735.18 KFM26423.1 - 0.012 14.9 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_16 PF13191.6 KFM26423.1 - 0.012 16.0 0.1 0.03 14.7 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.6 KFM26423.1 - 0.013 15.8 0.0 0.024 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KFM26423.1 - 0.018 14.9 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 KFM26423.1 - 0.023 15.2 0.0 0.037 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 KFM26423.1 - 0.025 14.4 0.0 0.046 13.5 0.0 1.5 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.9 KFM26423.1 - 0.04 12.7 0.0 0.06 12.1 0.0 1.1 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_14 PF13173.6 KFM26423.1 - 0.081 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain VirE PF05272.11 KFM26423.1 - 0.2 11.3 0.0 0.38 10.4 0.0 1.4 1 0 0 1 1 1 0 Virulence-associated protein E Nop PF01798.18 KFM26424.1 - 3.3e-77 259.0 3.0 3.4e-77 259.0 0.2 2.3 2 1 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KFM26424.1 - 6.3e-20 71.3 4.8 1.8e-19 69.9 4.8 1.9 1 0 0 1 1 1 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.11 KFM26424.1 - 0.061 13.4 9.8 0.11 12.5 9.8 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 ubiquitin PF00240.23 KFM26425.1 - 2.7e-34 116.7 0.5 3.5e-34 116.4 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 KFM26425.1 - 9.3e-32 108.7 9.4 1.4e-31 108.1 9.4 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 KFM26425.1 - 1.9e-16 59.6 0.8 2.9e-16 59.1 0.8 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KFM26425.1 - 2.6e-05 24.6 0.1 9.8e-05 22.7 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KFM26425.1 - 0.0028 17.6 0.0 0.0039 17.1 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 KFM26425.1 - 0.0031 17.8 0.1 0.0051 17.1 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KFM26425.1 - 0.0044 17.1 0.1 0.0086 16.2 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 KFM26425.1 - 0.006 16.6 1.2 1.7 8.7 0.2 2.2 2 0 0 2 2 2 2 Ubiquitin-like domain DUF2407 PF10302.9 KFM26425.1 - 0.031 14.8 0.1 0.034 14.7 0.1 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain PP2C PF00481.21 KFM26426.1 - 5.3e-57 193.4 0.0 9.3e-57 192.6 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KFM26426.1 - 0.00022 21.2 0.3 0.027 14.4 0.0 2.1 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Ni_hydr_CYTB PF01292.20 KFM26427.1 - 0.0034 17.0 6.1 0.053 13.1 0.1 3.1 3 0 0 3 3 3 1 Prokaryotic cytochrome b561 Glycophorin_A PF01102.18 KFM26427.1 - 0.0074 16.5 0.0 0.086 13.1 0.0 2.5 2 0 0 2 2 2 1 Glycophorin A EphA2_TM PF14575.6 KFM26427.1 - 0.017 16.0 0.5 35 5.4 0.0 3.7 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3B PF03376.14 KFM26427.1 - 0.055 13.7 0.4 0.32 11.2 0.0 2.4 2 0 0 2 2 2 0 Adenovirus E3B protein Laminin_II PF06009.12 KFM26427.1 - 0.071 13.1 0.3 10 6.1 0.0 2.2 2 0 0 2 2 2 0 Laminin Domain II DUF4748 PF15932.5 KFM26427.1 - 0.073 12.8 0.6 0.073 12.8 0.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4748) Tweety PF04906.13 KFM26427.1 - 0.22 10.2 0.0 0.22 10.2 0.0 3.0 2 1 0 3 3 3 0 Tweety Syndecan PF01034.20 KFM26427.1 - 1.2 9.1 0.0 1.2 9.1 0.0 3.1 3 0 0 3 3 3 0 Syndecan domain DUF5305 PF17231.2 KFM26427.1 - 2.1 7.7 5.0 22 4.4 0.2 4.0 4 1 1 5 5 5 0 Family of unknown function (DUF5305) DUF883 PF05957.13 KFM26427.1 - 2.2 8.9 6.1 6.1 7.5 0.0 3.2 4 1 0 4 4 3 0 Bacterial protein of unknown function (DUF883) SUR7 PF06687.12 KFM26427.1 - 2.9 7.5 14.0 1 9.0 0.6 3.2 3 1 0 3 3 3 0 SUR7/PalI family DUF4131 PF13567.6 KFM26427.1 - 3.7 7.2 15.6 4.7 6.8 0.1 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) RRM_1 PF00076.22 KFM26428.1 - 1.9e-40 136.5 0.0 3.5e-16 58.8 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFM26428.1 - 1.5e-07 31.0 0.0 0.095 12.3 0.0 3.1 1 1 2 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KFM26428.1 - 0.0016 18.5 0.1 6 7.0 0.0 3.4 3 1 0 3 3 3 1 Limkain b1 RRM_8 PF11835.8 KFM26428.1 - 0.0024 18.1 0.1 1.6 9.0 0.0 3.0 3 0 0 3 3 3 1 RRM-like domain RRM_3 PF08777.11 KFM26428.1 - 0.012 15.6 0.0 0.36 10.9 0.0 2.6 3 0 0 3 3 3 0 RNA binding motif RRM_7 PF16367.5 KFM26428.1 - 0.016 15.3 0.0 0.19 11.9 0.0 2.5 2 1 0 2 2 2 0 RNA recognition motif RNA_bind PF08675.11 KFM26428.1 - 0.022 14.8 0.0 3.7 7.6 0.0 2.9 2 1 0 2 2 2 0 RNA binding domain PHM7_cyt PF14703.6 KFM26428.1 - 0.1 12.8 0.0 0.35 11.1 0.0 1.9 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Form-deh_trans PF09163.11 KFM26429.1 - 0.2 11.4 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Formate dehydrogenase N, transmembrane Apolipoprotein PF01442.18 KFM26430.1 - 7.5e-08 32.5 8.7 3.5e-06 27.0 5.6 2.7 1 1 1 2 2 2 1 Apolipoprotein A1/A4/E domain Tape_meas_lam_C PF09718.10 KFM26430.1 - 1.5e-05 25.0 1.7 9.4 6.5 0.0 5.3 4 1 1 5 5 5 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) ApoLp-III PF07464.11 KFM26430.1 - 2.6e-05 24.3 6.2 0.59 10.2 0.1 3.2 2 1 1 3 3 3 2 Apolipophorin-III precursor (apoLp-III) DUF883 PF05957.13 KFM26430.1 - 8.2e-05 23.1 7.9 0.35 11.5 0.3 3.9 1 1 3 4 4 4 2 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 KFM26430.1 - 0.00012 22.5 20.3 1.1 9.9 7.0 4.2 1 1 1 2 2 2 2 YtxH-like protein MAP65_ASE1 PF03999.12 KFM26430.1 - 0.00018 20.4 1.7 0.2 10.3 0.2 2.9 1 1 1 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) QIL1 PF15884.5 KFM26430.1 - 0.0011 19.5 0.9 26 5.5 0.0 4.2 3 2 1 4 4 4 0 MICOS complex subunit MIC13, QIL1 FAM25 PF15825.5 KFM26430.1 - 0.0046 17.3 6.4 0.61 10.5 0.1 4.0 4 0 0 4 4 4 1 FAM25 family DUF2670 PF10875.8 KFM26430.1 - 0.0077 16.3 2.0 0.33 11.1 0.1 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF2670) T7SS_ESX_EspC PF10824.8 KFM26430.1 - 0.0099 16.3 0.8 0.43 11.1 0.1 2.9 3 0 0 3 3 3 1 Excreted virulence factor EspC, type VII ESX diderm Ribosomal_S3Ae PF01015.18 KFM26430.1 - 0.011 15.3 6.4 4.4 6.8 0.1 3.1 2 1 0 3 3 3 0 Ribosomal S3Ae family EspB PF05802.11 KFM26430.1 - 0.015 15.3 4.9 0.25 11.3 0.1 2.6 2 1 0 2 2 2 0 Enterobacterial EspB protein FinO_N PF12602.8 KFM26430.1 - 0.017 15.4 0.1 31 5.0 0.0 3.4 3 0 0 3 3 3 0 Fertility inhibition protein N terminal Bet_v_1 PF00407.19 KFM26430.1 - 0.023 14.6 1.6 0.073 13.0 0.5 1.9 1 1 1 2 2 2 0 Pathogenesis-related protein Bet v I family Phasin_2 PF09361.10 KFM26430.1 - 0.029 14.6 3.9 1.3 9.3 0.2 3.5 3 1 1 4 4 4 0 Phasin protein DUF4404 PF14357.6 KFM26430.1 - 0.069 13.8 8.9 0.74 10.5 0.2 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) Methyltrn_RNA_4 PF09936.9 KFM26430.1 - 0.082 12.8 1.6 0.7 9.7 0.1 2.4 1 1 2 3 3 3 0 SAM-dependent RNA methyltransferase ApoO PF09769.9 KFM26430.1 - 0.11 12.5 0.2 26 4.8 0.1 2.9 2 1 0 2 2 2 0 Apolipoprotein O STELLO PF03385.17 KFM26430.1 - 0.13 11.0 0.1 0.2 10.5 0.1 1.3 1 0 0 1 1 1 0 STELLO glycosyltransferases YbaB_DNA_bd PF02575.16 KFM26430.1 - 0.14 12.4 8.4 23 5.3 0.1 4.4 2 1 3 5 5 5 0 YbaB/EbfC DNA-binding family Alanine_zipper PF11839.8 KFM26430.1 - 0.22 11.9 9.9 2.6 8.5 0.2 4.2 5 0 0 5 5 4 0 Alanine-zipper, major outer membrane lipoprotein ISG65-75 PF11727.8 KFM26430.1 - 0.3 10.3 13.3 0.23 10.7 6.7 2.3 1 1 2 3 3 3 0 Invariant surface glycoprotein Grg1 PF11034.8 KFM26430.1 - 0.36 11.1 8.0 0.5 10.6 0.8 3.7 3 2 1 4 4 4 0 Glucose-repressible protein Grg1 ORF11CD3 PF10549.9 KFM26430.1 - 0.37 11.0 6.3 83 3.4 0.1 4.3 3 1 1 4 4 4 0 ORF11CD3 domain DUF1451 PF07295.11 KFM26430.1 - 0.43 10.6 8.9 0.99 9.4 0.3 3.2 2 1 1 3 3 3 0 Zinc-ribbon containing domain SIMPL PF04402.14 KFM26430.1 - 0.45 11.0 16.4 17 5.8 3.4 4.0 1 1 3 4 4 4 0 Protein of unknown function (DUF541) Dodecin PF07311.12 KFM26430.1 - 0.48 10.7 13.2 12 6.3 0.1 4.7 4 1 1 5 5 5 0 Dodecin PIN_8 PF18476.1 KFM26430.1 - 0.49 10.2 9.4 1.4 8.7 1.5 2.2 1 1 1 2 2 2 0 PIN like domain DUF2959 PF11172.8 KFM26430.1 - 0.81 9.8 9.2 11 6.1 0.4 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2959) eIF3_N PF09440.10 KFM26430.1 - 1.9 8.9 4.3 3.1 8.2 0.3 2.6 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain HicB_lk_antitox PF15919.5 KFM26430.1 - 4 7.6 5.1 8.7 6.5 0.1 3.2 3 1 1 4 4 4 0 HicB_like antitoxin of bacterial toxin-antitoxin system Calpain_u2 PF16648.5 KFM26430.1 - 6 7.4 10.0 11 6.6 0.2 3.1 3 0 0 3 3 3 0 Unstructured region on Calpain-3 Vps51 PF08700.11 KFM26431.1 - 1e-14 54.4 0.0 2e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.12 KFM26431.1 - 8.9e-08 31.2 0.1 1.4e-07 30.6 0.1 1.2 1 0 0 1 1 1 1 Dor1-like family Sec5 PF15469.6 KFM26431.1 - 1.1e-05 25.3 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec5 COG2 PF06148.11 KFM26431.1 - 0.00014 22.0 0.1 0.00041 20.4 0.3 1.7 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 CENP-F_leu_zip PF10473.9 KFM26431.1 - 0.0093 16.0 0.1 0.019 15.0 0.1 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 COG5 PF10392.9 KFM26431.1 - 0.075 13.2 0.5 0.15 12.3 0.5 1.5 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Zw10 PF06248.13 KFM26431.1 - 0.17 10.4 0.0 0.25 9.8 0.0 1.2 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 UPF0242 PF06785.11 KFM26431.1 - 0.21 11.6 0.0 0.33 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus cobW PF02492.19 KFM26432.1 - 4.8e-57 192.4 0.8 5.9e-57 192.1 0.8 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KFM26432.1 - 2.5e-16 59.4 0.1 8.7e-16 57.6 0.0 1.9 2 0 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 KFM26432.1 - 7.9e-06 25.9 0.0 0.039 13.8 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase MobB PF03205.14 KFM26432.1 - 5e-05 23.2 0.0 0.00012 22.0 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.6 KFM26432.1 - 0.004 17.4 0.1 0.009 16.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 KFM26432.1 - 0.013 15.0 0.4 2.8 7.4 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_23 PF13476.6 KFM26432.1 - 0.015 15.8 1.4 0.029 14.9 1.5 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFM26432.1 - 0.016 15.6 0.0 0.042 14.2 0.0 1.7 2 0 0 2 2 1 0 AAA ATPase domain AAA_29 PF13555.6 KFM26432.1 - 0.022 14.5 0.0 0.054 13.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 KFM26432.1 - 0.022 15.0 0.0 0.057 13.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KFM26432.1 - 0.024 13.7 0.0 0.05 12.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.6 KFM26432.1 - 0.026 15.1 0.1 0.088 13.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KFM26432.1 - 0.027 14.5 0.0 0.048 13.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KFM26432.1 - 0.039 13.7 0.0 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 KFM26432.1 - 0.043 13.9 0.0 0.058 13.5 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 KFM26432.1 - 0.047 13.9 0.1 0.084 13.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KFM26432.1 - 0.059 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 KFM26432.1 - 0.073 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase MeaB PF03308.16 KFM26432.1 - 0.079 11.9 0.2 1.5 7.7 0.0 2.6 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF2075 PF09848.9 KFM26432.1 - 0.083 12.1 0.0 0.19 11.0 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 KFM26432.1 - 0.11 13.0 0.2 0.21 12.1 0.2 1.7 1 1 0 1 1 1 0 ABC transporter TsaE PF02367.17 KFM26432.1 - 0.13 12.3 0.0 0.33 11.0 0.0 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KFM26432.1 - 0.15 12.0 0.1 0.41 10.6 0.1 1.7 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.23 KFM26432.1 - 0.16 12.0 0.3 0.84 9.7 0.3 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase PQ-loop PF04193.14 KFM26433.1 - 1.9e-35 120.4 10.6 1.7e-19 69.4 5.7 2.5 2 0 0 2 2 2 2 PQ loop repeat KleE PF17394.2 KFM26433.1 - 0.18 12.1 0.1 0.18 12.1 0.1 2.7 3 0 0 3 3 3 0 Uncharacterized KleE stable inheritance protein DNA_pol_A_exo1 PF01612.20 KFM26434.1 - 2.4e-17 63.2 0.0 3.3e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease Aa_trans PF01490.18 KFM26435.1 - 2.8e-24 85.6 27.0 3.7e-24 85.2 27.0 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MMR_HSR1 PF01926.23 KFM26436.1 - 2.1e-19 69.7 0.1 1.1e-15 57.7 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase GN3L_Grn1 PF08701.11 KFM26436.1 - 2.7e-18 65.8 19.4 2.7e-18 65.8 19.4 2.2 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase FeoB_N PF02421.18 KFM26436.1 - 3e-13 49.6 0.0 1.6e-08 34.3 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KFM26436.1 - 4.7e-07 29.9 1.8 0.003 17.5 0.6 2.6 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KFM26436.1 - 0.00024 20.7 0.1 0.0042 16.6 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KFM26436.1 - 0.0027 17.8 5.6 0.0029 17.7 1.3 3.0 2 2 0 2 2 2 1 Dynamin family AIG1 PF04548.16 KFM26436.1 - 0.017 14.4 0.0 0.058 12.7 0.0 1.9 2 0 0 2 2 2 0 AIG1 family MeaB PF03308.16 KFM26436.1 - 0.065 12.2 0.1 0.065 12.2 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 KFM26436.1 - 0.065 13.8 1.4 0.57 10.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Arf PF00025.21 KFM26436.1 - 0.087 12.3 0.2 0.9 9.0 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_16 PF13191.6 KFM26436.1 - 0.097 13.1 5.8 0.56 10.6 0.0 2.8 2 1 0 2 2 2 0 AAA ATPase domain DDE_Tnp_ISL3 PF01610.17 KFM26436.1 - 2 8.1 8.0 3.7 7.2 8.0 1.4 1 0 0 1 1 1 0 Transposase GH-E PF14410.6 KFM26436.1 - 2.6 8.5 6.2 1.2 9.6 0.0 2.9 3 0 0 3 3 3 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues EMP24_GP25L PF01105.24 KFM26437.1 - 7e-41 140.2 0.0 8.4e-41 139.9 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD ATP-synt_D PF01813.17 KFM26439.1 - 3.2e-71 239.2 1.4 4.2e-71 238.8 1.4 1.2 1 0 0 1 1 1 1 ATP synthase subunit D Prefoldin PF02996.17 KFM26439.1 - 0.25 11.3 7.3 0.22 11.5 0.3 2.8 3 0 0 3 3 3 0 Prefoldin subunit Pkinase PF00069.25 KFM26440.1 - 2.2e-62 210.8 0.0 2.9e-62 210.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM26440.1 - 2.9e-29 102.1 0.0 4.9e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFM26440.1 - 0.0001 21.7 0.1 0.00017 21.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFM26440.1 - 0.0019 17.2 1.0 0.004 16.1 0.2 1.9 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 KFM26440.1 - 0.0066 15.8 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 KFM26440.1 - 0.074 12.7 0.2 0.19 11.3 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 UCH PF00443.29 KFM26442.1 - 1.4e-34 119.8 0.0 1.7e-34 119.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFM26442.1 - 0.0045 16.6 0.0 0.017 14.8 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase AAA PF00004.29 KFM26443.1 - 7.3e-24 84.7 0.0 3.6e-11 43.6 0.0 3.3 2 1 1 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFM26443.1 - 1e-05 25.2 3.8 1.3e-05 24.9 0.0 3.0 4 0 0 4 4 4 1 AAA+ lid domain gag-asp_proteas PF13975.6 KFM26443.1 - 0.055 14.0 0.0 0.15 12.6 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease SIMPL PF04402.14 KFM26444.1 - 5.4e-42 144.5 11.6 6.1e-42 144.3 11.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) DFP PF04127.15 KFM26445.1 - 0.0025 17.7 2.9 0.0048 16.7 2.9 1.6 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein MTBP_N PF14918.6 KFM26445.1 - 0.054 13.0 3.0 0.084 12.3 3.0 1.3 1 0 0 1 1 1 0 MDM2-binding DUF1664 PF07889.12 KFM26445.1 - 0.11 12.6 4.0 0.13 12.3 1.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin PF00804.25 KFM26445.1 - 0.17 11.5 10.6 0.069 12.8 6.3 2.1 2 0 0 2 2 2 0 Syntaxin eIF3_N PF09440.10 KFM26445.1 - 0.71 10.3 3.8 0.58 10.6 1.7 1.9 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain Spc7 PF08317.11 KFM26445.1 - 1.2 8.0 12.3 2.6 6.8 12.3 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein TraG_N PF07916.11 KFM26446.1 - 1.7 7.4 11.1 2.6 6.8 11.1 1.4 1 0 0 1 1 1 0 TraG-like protein, N-terminal region TMF_TATA_bd PF12325.8 KFM26446.1 - 7.1 6.9 8.0 14 6.0 0.9 2.7 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding ABC_tran PF00005.27 KFM26447.1 - 5.8e-34 117.6 0.0 1.1e-33 116.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KFM26447.1 - 2.4e-28 99.6 3.0 3.1e-28 99.2 3.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_16 PF13191.6 KFM26447.1 - 2.9e-05 24.5 0.4 7e-05 23.3 0.4 1.7 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 KFM26447.1 - 0.0001 21.8 0.1 0.0042 16.5 0.1 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KFM26447.1 - 0.0032 17.8 0.0 0.028 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KFM26447.1 - 0.0034 17.1 0.2 0.0089 15.8 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 KFM26447.1 - 0.0046 16.7 0.1 0.016 14.9 0.1 1.9 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KFM26447.1 - 0.005 16.1 0.1 0.015 14.6 0.1 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_21 PF13304.6 KFM26447.1 - 0.0059 16.5 0.1 0.021 14.6 0.1 1.8 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF815 PF05673.13 KFM26447.1 - 0.007 15.5 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 KFM26447.1 - 0.024 14.6 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 KFM26447.1 - 0.037 14.2 0.3 0.098 12.8 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.6 KFM26447.1 - 0.038 13.7 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain PsaM PF07465.13 KFM26447.1 - 0.041 13.6 0.2 0.21 11.3 0.2 2.3 1 0 0 1 1 1 0 Photosystem I protein M (PsaM) AAA_18 PF13238.6 KFM26447.1 - 0.047 14.2 0.0 0.092 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KFM26447.1 - 0.071 13.2 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_15 PF13175.6 KFM26447.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 KFM26447.1 - 0.12 12.0 0.1 0.34 10.5 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KFM26447.1 - 0.12 12.3 0.2 0.89 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) G-alpha PF00503.20 KFM26447.1 - 0.15 11.2 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit DUF87 PF01935.17 KFM26447.1 - 0.18 11.8 0.2 0.34 11.0 0.2 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_28 PF13521.6 KFM26447.1 - 1.3 9.2 4.8 0.54 10.5 0.2 2.5 2 1 2 4 4 3 0 AAA domain Rieske PF00355.26 KFM26448.1 - 3.4e-18 65.4 0.0 7.6e-18 64.2 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 KFM26448.1 - 8e-06 25.7 0.0 1.4e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain LRR_4 PF12799.7 KFM26449.1 - 1.2e-38 130.4 12.5 6.3e-08 32.8 0.2 6.3 6 0 0 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFM26449.1 - 1.1e-20 73.1 25.3 8e-07 28.7 3.9 6.0 5 1 2 7 7 7 5 Leucine rich repeat LRR_9 PF14580.6 KFM26449.1 - 3.8e-18 65.6 0.6 3.1e-08 33.3 0.0 3.9 2 1 2 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.6 KFM26449.1 - 7.4e-05 22.5 13.8 3.7 7.8 0.0 6.8 6 1 1 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.33 KFM26449.1 - 0.00023 21.3 24.0 3.5 8.5 0.2 8.3 8 1 0 8 8 8 3 Leucine Rich Repeat Trs65 PF12735.7 KFM26449.1 - 0.096 12.1 0.0 0.27 10.6 0.0 1.6 2 0 0 2 2 2 0 TRAPP trafficking subunit Trs65 DUF4911 PF16256.5 KFM26449.1 - 0.1 12.6 0.2 0.8 9.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4911) FAD_binding_3 PF01494.19 KFM26450.1 - 1.7e-18 67.0 0.5 1.8e-08 34.0 0.3 2.3 2 1 0 2 2 2 2 FAD binding domain FHA PF00498.26 KFM26450.1 - 4.1e-10 39.8 0.0 7.6e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KFM26450.1 - 6.7e-05 23.1 0.0 0.00015 22.1 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Lycopene_cycl PF05834.12 KFM26450.1 - 0.00012 21.3 0.1 0.013 14.6 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KFM26450.1 - 0.0005 20.3 2.5 0.0018 18.5 1.4 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFM26450.1 - 0.0012 18.5 6.5 0.077 12.6 3.9 2.5 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFM26450.1 - 0.0017 17.6 0.9 0.05 12.8 0.3 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFM26450.1 - 0.011 14.8 2.7 0.031 13.4 2.7 1.7 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KFM26450.1 - 0.028 13.7 0.1 0.056 12.7 0.1 1.4 1 0 0 1 1 1 0 Thi4 family SE PF08491.10 KFM26450.1 - 0.12 11.4 0.0 5.1 6.1 0.0 2.3 2 0 0 2 2 2 0 Squalene epoxidase Trp_halogenase PF04820.14 KFM26450.1 - 0.19 10.6 1.1 5.9 5.6 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase DUF1338 PF07063.13 KFM26451.1 - 8.4e-64 215.8 0.0 9.8e-63 212.3 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1338) TPT PF03151.16 KFM26452.1 - 2.9e-22 79.4 11.8 3.5e-22 79.1 11.8 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KFM26452.1 - 0.0025 18.0 9.1 0.0025 18.0 9.1 2.3 2 0 0 2 2 2 1 EamA-like transporter family Ycf4 PF02392.16 KFM26452.1 - 0.79 9.3 4.8 0.14 11.7 0.8 1.7 2 0 0 2 2 2 0 Ycf4 DEAD PF00270.29 KFM26454.1 - 7.7e-15 55.1 0.0 8.3e-15 55.0 0.0 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KFM26454.1 - 0.00031 20.8 0.0 0.00037 20.5 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HHH_5 PF14520.6 KFM26455.1 - 0.00046 20.7 0.0 0.0011 19.5 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain GcnA_N PF18229.1 KFM26455.1 - 0.062 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 N-acetyl-beta-D-glucosaminidase N-terminal domain AhpC-TSA PF00578.21 KFM26456.1 - 5.4e-40 136.2 0.0 8e-40 135.6 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KFM26456.1 - 3.4e-18 65.8 0.0 4e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KFM26456.1 - 2.2e-15 56.2 0.0 4.3e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 KFM26456.1 - 0.027 14.4 0.0 0.087 12.7 0.0 1.7 2 0 0 2 2 2 0 SCO1/SenC tRNA_edit PF04073.15 KFM26457.1 - 6.1e-16 58.6 0.0 6.6e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain 60KD_IMP PF02096.20 KFM26458.1 - 3e-53 180.1 0.0 4e-53 179.7 0.0 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein SAA PF00277.18 KFM26458.1 - 0.18 12.3 1.8 0.32 11.5 1.4 1.6 1 1 0 1 1 1 0 Serum amyloid A protein Peptidase_S9 PF00326.21 KFM26459.1 - 1.2e-09 37.9 0.0 0.00023 20.7 0.0 3.0 3 0 0 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KFM26459.1 - 1.5e-08 34.6 0.0 4.6e-08 33.0 0.0 1.7 1 1 1 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 KFM26459.1 - 4.3e-07 29.7 0.1 9.3e-07 28.6 0.1 1.6 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 KFM26459.1 - 8.2e-07 29.8 11.8 1.5e-06 29.0 11.8 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFM26459.1 - 7.8e-05 22.1 0.4 0.00045 19.6 0.2 2.2 1 1 0 2 2 2 1 Serine aminopeptidase, S33 AXE1 PF05448.12 KFM26459.1 - 0.00036 19.3 0.0 0.00057 18.6 0.0 1.3 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 KFM26459.1 - 0.00061 19.5 0.6 0.0041 16.8 0.6 2.0 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.13 KFM26459.1 - 0.0012 18.7 0.6 0.002 18.0 0.6 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2048 PF09752.9 KFM26459.1 - 0.016 14.3 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 PhoPQ_related PF10142.9 KFM26459.1 - 0.13 10.9 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Pepdidase_M14_N PF18027.1 KFM26462.1 - 3.3e-34 117.5 0.0 5e-34 116.9 0.0 1.3 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain Peptidase_M14 PF00246.24 KFM26462.1 - 1.2e-21 77.8 0.0 3.9e-21 76.1 0.0 1.8 1 1 0 1 1 1 1 Zinc carboxypeptidase ANAPC3 PF12895.7 KFM26463.1 - 4.6e-18 65.2 2.0 1.1e-15 57.6 0.5 3.1 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 KFM26463.1 - 1.1e-12 47.2 0.0 0.1 12.4 0.0 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 KFM26463.1 - 1.7e-12 46.4 21.3 0.048 13.8 0.0 9.1 12 0 0 12 12 11 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFM26463.1 - 3.3e-09 36.8 41.8 0.097 13.5 0.4 10.1 7 2 5 12 12 11 4 Tetratricopeptide repeat TPR_19 PF14559.6 KFM26463.1 - 3.9e-06 27.3 15.3 0.0036 17.8 0.0 6.0 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFM26463.1 - 2.1e-05 24.3 0.0 13 6.3 0.0 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFM26463.1 - 5.2e-05 23.3 2.0 7.9 7.1 0.0 6.3 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFM26463.1 - 8.8e-05 23.1 39.5 0.0021 18.7 0.0 7.5 6 2 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFM26463.1 - 0.0016 18.3 7.3 1.5 9.1 0.0 4.6 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFM26463.1 - 0.0018 17.9 1.0 16 5.2 0.0 5.6 3 2 3 6 6 6 0 TPR repeat TPR_12 PF13424.6 KFM26463.1 - 0.0049 17.1 0.3 0.0049 17.1 0.3 6.4 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_15 PF13429.6 KFM26463.1 - 0.012 14.8 5.0 0.22 10.7 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat YAcAr PF10686.9 KFM26463.1 - 0.012 15.5 6.3 0.013 15.4 1.2 2.9 3 0 0 3 3 3 0 YspA, cpYpsA-related SLOG family TPR_6 PF13174.6 KFM26463.1 - 0.034 14.8 8.8 46 4.9 0.0 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF4810 PF16068.5 KFM26463.1 - 0.055 14.0 0.1 4.8 7.8 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4810) RSN1_7TM PF02714.15 KFM26464.1 - 0.0077 15.6 0.0 0.027 13.8 0.0 1.8 1 1 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate Peptidase_S8 PF00082.22 KFM26465.1 - 1.5e-75 254.3 0.2 2.3e-75 253.6 0.2 1.3 1 0 0 1 1 1 1 Subtilase family TPPII PF12580.8 KFM26465.1 - 9.8e-51 171.9 0.0 1.5e-50 171.3 0.0 1.3 1 0 0 1 1 1 1 Tripeptidyl peptidase II PALP PF00291.25 KFM26466.1 - 1.6e-70 237.8 4.4 2.9e-70 237.0 4.4 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 KFM26466.1 - 1.1e-19 70.0 0.0 1.4e-08 34.4 0.0 2.4 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase POTRA_3 PF17287.2 KFM26466.1 - 0.025 14.1 0.0 0.056 12.9 0.0 1.5 1 0 0 1 1 1 0 POTRA domain V-ATPase_C PF03223.15 KFM26467.1 - 1.5e-104 350.4 0.0 1.8e-104 350.1 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C DUF768 PF05589.11 KFM26467.1 - 0.074 13.1 0.2 0.45 10.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF768) PITH PF06201.13 KFM26470.1 - 8.6e-30 104.0 0.0 1e-29 103.7 0.0 1.1 1 0 0 1 1 1 1 PITH domain MOSC_N PF03476.16 KFM26471.1 - 4.3e-33 113.7 0.0 1.2e-32 112.3 0.0 1.8 2 0 0 2 2 2 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 KFM26471.1 - 5e-25 88.0 0.0 8.2e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 MOSC domain Rtf2 PF04641.12 KFM26472.1 - 2.2e-31 109.2 0.0 2.9e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 KFM26472.1 - 0.00011 22.0 0.0 0.0052 16.6 0.0 2.3 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 KFM26472.1 - 0.071 13.1 1.1 0.43 10.7 0.9 2.3 1 1 1 2 2 2 0 RING-type zinc-finger zf-NOSIP PF15906.5 KFM26472.1 - 0.079 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein PFK PF00365.20 KFM26473.1 - 2.1e-58 197.9 0.5 3.1e-58 197.4 0.5 1.2 1 0 0 1 1 1 1 Phosphofructokinase mit_SMPDase PF14724.6 KFM26476.1 - 0.00015 19.9 0.0 0.012 13.6 0.0 2.4 2 0 0 2 2 2 2 Mitochondrial-associated sphingomyelin phosphodiesterase ANAPC4_WD40 PF12894.7 KFM26477.1 - 8.7e-12 45.2 0.2 3.3e-05 24.1 0.0 4.8 2 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFM26477.1 - 8.3e-06 26.5 11.7 0.33 11.9 0.0 5.9 5 1 1 6 6 6 2 WD domain, G-beta repeat DUF2844 PF11005.8 KFM26478.1 - 0.00023 21.2 0.0 0.00059 19.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2844) CTD_bind PF04818.13 KFM26478.1 - 0.00073 20.3 0.0 0.0017 19.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. MFS_1 PF07690.16 KFM26479.1 - 5.6e-25 88.0 30.6 5.6e-25 88.0 30.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_S41 PF03572.18 KFM26480.1 - 4.2e-38 130.5 0.0 7.3e-38 129.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S41 Myb_DNA-binding PF00249.31 KFM26480.1 - 1.3e-12 47.7 0.2 2.3e-12 46.9 0.2 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain PDZ_6 PF17820.1 KFM26480.1 - 2.7e-07 30.3 0.1 7.9e-07 28.8 0.1 1.8 1 0 0 1 1 1 1 PDZ domain Myb_DNA-bind_6 PF13921.6 KFM26480.1 - 0.0034 17.6 0.1 0.007 16.6 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain PDZ_2 PF13180.6 KFM26480.1 - 0.028 14.7 0.0 0.088 13.1 0.0 1.9 1 0 0 1 1 1 0 PDZ domain Acyltransferase PF01553.21 KFM26481.1 - 2.1e-15 56.6 0.0 3.3e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase YCII PF03795.14 KFM26483.1 - 7.3e-09 35.9 0.0 9.8e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 YCII-related domain PS_Dcarbxylase PF02666.15 KFM26483.1 - 0.055 13.0 0.0 0.069 12.7 0.0 1.1 1 0 0 1 1 1 0 Phosphatidylserine decarboxylase NCBP3 PF10309.9 KFM26484.1 - 0.00049 19.9 0.0 0.00073 19.3 0.0 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 TRAPPC9-Trs120 PF08626.11 KFM26485.1 - 5.2e-23 80.5 0.0 1.1e-12 46.3 0.0 2.9 2 1 0 3 3 3 3 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Endonuc-BsobI PF09194.10 KFM26485.1 - 0.21 10.8 0.0 0.3 10.2 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease BsobI Cyclin_N PF00134.23 KFM26487.1 - 1.1e-13 51.1 0.0 4.4e-13 49.1 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain DUF1336 PF07059.12 KFM26488.1 - 6.5e-50 170.3 0.0 8.1e-50 170.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) Methyltransf_4 PF02390.17 KFM26489.1 - 1.3e-27 96.4 0.0 4.2e-27 94.7 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_25 PF13649.6 KFM26489.1 - 0.00059 20.5 0.0 0.001 19.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM26489.1 - 0.0062 16.4 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF3360 PF11840.8 KFM26489.1 - 0.025 13.3 0.1 0.033 12.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3360) Methyltransf_32 PF13679.6 KFM26489.1 - 0.26 11.3 0.0 0.34 10.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Q_salvage PF10343.9 KFM26491.1 - 0.01 15.5 0.0 0.012 15.2 0.0 1.3 1 1 0 1 1 1 0 Potential Queuosine, Q, salvage protein family Ipi1_N PF12333.8 KFM26492.1 - 4.3e-10 40.1 0.0 9.2e-08 32.6 0.0 3.4 3 0 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation Cohesin_HEAT PF12765.7 KFM26492.1 - 0.022 15.0 0.1 0.051 13.9 0.1 1.7 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion ADH_zinc_N PF00107.26 KFM26494.1 - 1.2e-24 86.8 1.1 2.3e-24 85.8 1.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFM26494.1 - 1.3e-19 71.6 0.0 2.7e-19 70.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFM26494.1 - 2e-11 43.7 0.0 3.3e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KFM26494.1 - 0.012 15.0 0.6 0.012 15.0 0.6 1.6 2 0 0 2 2 2 0 short chain dehydrogenase TrkA_N PF02254.18 KFM26494.1 - 0.048 13.9 0.0 0.086 13.1 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.21 KFM26494.1 - 0.13 11.6 2.7 0.21 10.8 2.7 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ACP_syn_III_C PF08541.10 KFM26494.1 - 0.89 9.8 3.1 0.64 10.2 0.5 2.0 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal XPG_I PF00867.18 KFM26495.1 - 1.8e-20 73.1 0.0 2.7e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 KFM26495.1 - 0.0003 20.4 0.1 0.00044 19.8 0.1 1.1 1 0 0 1 1 1 1 XPG domain containing XPG_N PF00752.17 KFM26495.1 - 0.012 16.1 0.0 0.019 15.4 0.0 1.3 1 0 0 1 1 1 0 XPG N-terminal domain TPR_14 PF13428.6 KFM26495.1 - 0.012 16.4 4.6 0.043 14.6 4.6 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFM26495.1 - 0.013 15.5 0.7 0.034 14.3 0.7 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_9 PF13371.6 KFM26495.1 - 0.3 11.2 4.3 1.3 9.2 4.3 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Rab5ip PF07019.12 KFM26496.1 - 0.00026 21.5 0.3 0.00028 21.4 0.3 1.2 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Lipase_3 PF01764.25 KFM26497.1 - 1.1e-22 80.5 0.0 4.7e-22 78.4 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) DUF4235 PF14019.6 KFM26497.1 - 1.2 9.2 14.2 0.52 10.4 3.4 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4235) AA_kinase PF00696.28 KFM26498.1 - 1.1e-44 152.9 0.0 1.6e-44 152.3 0.0 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.25 KFM26498.1 - 3.4e-08 33.1 1.7 0.0014 18.4 0.1 3.1 3 0 0 3 3 3 2 ACT domain ACT_7 PF13840.6 KFM26498.1 - 1.1e-05 25.1 0.5 0.0079 16.0 0.0 2.5 2 0 0 2 2 2 2 ACT domain ACT_5 PF13710.6 KFM26498.1 - 0.0016 18.3 0.6 0.27 11.1 0.1 3.0 3 0 0 3 3 3 1 ACT domain DUF563 PF04577.14 KFM26499.1 - 2.4e-17 63.8 0.0 5e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Dus PF01207.17 KFM26501.1 - 2.7e-55 187.6 0.0 3.6e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) LSM PF01423.22 KFM26503.1 - 3.9e-05 23.3 0.0 4.6e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 LSM domain Ribosomal_S24e PF01282.19 KFM26504.1 - 5.2e-36 122.4 0.4 1.2e-35 121.2 0.0 1.7 1 1 1 2 2 2 1 Ribosomal protein S24e ETF_QO PF05187.13 KFM26505.1 - 7.9e-46 154.5 0.0 1.4e-45 153.7 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S NAD_binding_8 PF13450.6 KFM26505.1 - 6.2e-07 29.5 0.0 6.2e-07 29.5 0.0 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFM26505.1 - 1.5e-06 28.0 0.7 0.0001 22.0 0.1 2.5 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFM26505.1 - 1.9e-06 27.3 0.2 0.00026 20.2 0.4 2.2 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KFM26505.1 - 2.2e-05 23.8 0.6 5.1e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 KFM26505.1 - 4.6e-05 22.8 0.0 6.3e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFM26505.1 - 0.00013 20.9 0.1 0.00018 20.3 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.6 KFM26505.1 - 0.00022 21.2 0.0 0.00057 19.9 0.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KFM26505.1 - 0.00022 20.6 0.0 0.00031 20.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KFM26505.1 - 0.00035 19.9 0.3 0.00049 19.4 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KFM26505.1 - 0.00036 19.7 0.2 0.00065 18.9 0.0 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein Fer4_7 PF12838.7 KFM26505.1 - 0.0016 19.0 0.7 0.0053 17.3 0.7 1.9 1 0 0 1 1 1 1 4Fe-4S dicluster domain K_oxygenase PF13434.6 KFM26505.1 - 0.026 13.7 0.0 0.037 13.2 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 KFM26505.1 - 0.034 13.5 0.1 0.13 11.6 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 KFM26505.1 - 0.15 11.1 0.1 0.24 10.4 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Rft-1 PF04506.13 KFM26506.1 - 1.7e-79 267.9 0.0 3.3e-79 267.0 0.0 1.5 1 1 0 1 1 1 1 Rft protein LRR_9 PF14580.6 KFM26507.1 - 6.8e-63 211.3 0.5 9.2e-63 210.9 0.5 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 KFM26507.1 - 6.3e-10 38.7 23.2 1.5e-05 24.7 4.0 3.7 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KFM26507.1 - 5e-09 36.3 12.5 0.00038 20.8 3.7 3.7 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) Nbl1_Borealin_N PF10444.9 KFM26508.1 - 1.9e-06 27.4 0.4 5.7e-06 25.9 0.4 1.9 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal DUF572 PF04502.13 KFM26509.1 - 1.1e-53 183.0 0.0 1.5e-53 182.6 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) FH2 PF02181.23 KFM26509.1 - 8.1e-37 127.2 0.0 6.1e-36 124.3 0.0 1.9 1 1 0 1 1 1 1 Formin Homology 2 Domain Drf_GBD PF06371.13 KFM26509.1 - 0.0006 19.4 0.0 0.00088 18.9 0.0 1.2 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Sporozoite_P67 PF05642.11 KFM26509.1 - 4 5.4 4.7 7 4.6 4.7 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF3506 PF12014.8 KFM26510.1 - 4.1e-08 33.3 0.0 2.6e-07 30.8 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3506) F-box PF00646.33 KFM26510.1 - 0.00061 19.6 0.0 0.0026 17.6 0.0 2.1 2 0 0 2 2 2 1 F-box domain AhpC-TSA_2 PF13911.6 KFM26511.1 - 4.7e-11 42.8 0.0 6.1e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Ribosomal_S9 PF00380.19 KFM26512.1 - 1.6e-32 112.6 0.2 1.8e-32 112.4 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 CHCH PF06747.13 KFM26513.1 - 7.4e-08 32.3 5.4 8.4e-06 25.8 1.0 2.3 2 0 0 2 2 2 2 CHCH domain CX9C PF16860.5 KFM26513.1 - 0.0003 20.7 6.3 0.027 14.5 1.1 2.1 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 KFM26513.1 - 0.025 14.9 5.7 0.29 11.5 0.2 2.7 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 NDUF_B7 PF05676.13 KFM26513.1 - 0.23 11.2 4.6 5.9 6.7 1.1 2.3 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) G6PD_C PF02781.16 KFM26514.1 - 5.5e-113 377.0 0.0 6.9e-113 376.6 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KFM26514.1 - 2.2e-56 191.3 0.0 3.2e-56 190.7 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Pilt PF15453.6 KFM26514.1 - 0.056 12.8 0.1 0.091 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions Zip PF02535.22 KFM26515.1 - 2.6e-30 105.8 12.0 9.4e-30 104.0 12.0 1.7 1 1 0 1 1 1 1 ZIP Zinc transporter DUF4381 PF14316.6 KFM26515.1 - 1.7 8.8 11.0 0.08 13.2 1.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) FF PF01846.19 KFM26516.1 - 1.9e-18 66.3 1.8 4.1e-06 26.9 0.0 5.2 4 1 1 5 5 5 4 FF domain WW PF00397.26 KFM26516.1 - 2e-05 24.6 5.8 4.3e-05 23.5 5.8 1.6 1 0 0 1 1 1 1 WW domain RhoGAP-FF1 PF16512.5 KFM26516.1 - 0.0015 19.2 0.0 0.019 15.6 0.0 2.6 3 0 0 3 3 3 1 p190-A and -B Rho GAPs FF domain DUF3584 PF12128.8 KFM26516.1 - 2.1 5.8 8.2 2.8 5.4 8.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) NAC PF01849.18 KFM26517.1 - 2e-22 78.9 2.7 9.7e-22 76.7 1.5 2.2 2 0 0 2 2 2 1 NAC domain UBA PF00627.31 KFM26517.1 - 0.015 15.2 0.1 0.037 13.9 0.1 1.7 1 0 0 1 1 1 0 UBA/TS-N domain YL1 PF05764.13 KFM26517.1 - 0.27 11.3 10.6 0.43 10.7 10.6 1.4 1 1 0 1 1 1 0 YL1 nuclear protein Sporozoite_P67 PF05642.11 KFM26517.1 - 1.6 6.7 10.7 1.8 6.6 4.8 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Glyco_transf_49 PF13896.6 KFM26519.1 - 4.4e-44 151.2 0.0 3.1e-43 148.4 0.0 1.9 1 1 0 1 1 1 1 Glycosyl-transferase for dystroglycan Glycos_transf_2 PF00535.26 KFM26519.1 - 0.0025 17.6 0.0 0.0048 16.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 KFM26519.1 - 0.057 12.9 0.0 0.094 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 SMC_N PF02463.19 KFM26520.1 - 5.8e-78 261.3 0.0 7e-78 261.0 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFM26520.1 - 3.2e-11 43.6 0.0 4.4e-05 23.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_hinge PF06470.13 KFM26520.1 - 1.2e-10 41.8 0.1 5.1e-08 33.2 0.0 2.9 1 1 1 2 2 2 2 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 KFM26520.1 - 4.4e-09 37.1 7.3 4.4e-09 37.1 7.3 3.2 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KFM26520.1 - 9.9e-06 25.5 0.1 9.9e-06 25.5 0.1 1.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KFM26520.1 - 1e-05 25.1 0.0 2e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 KFM26520.1 - 0.0045 17.5 0.5 0.39 11.2 0.0 3.3 3 0 0 3 3 3 1 ABC transporter Snapin_Pallidin PF14712.6 KFM26520.1 - 1.2 9.6 11.2 26 5.3 0.1 4.7 3 1 3 6 6 6 0 Snapin/Pallidin Pkinase PF00069.25 KFM26521.1 - 9.2e-17 61.3 0.0 2.9e-16 59.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 KFM26521.1 - 3.9e-07 30.7 15.9 0.0074 17.1 0.2 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat Pkinase_Tyr PF07714.17 KFM26521.1 - 7.8e-05 22.1 0.0 0.00015 21.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM26521.1 - 0.0076 15.6 0.0 0.016 14.6 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KFM26521.1 - 0.0094 15.9 4.7 0.026 14.5 0.0 3.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family DNA_processg_A PF02481.15 KFM26521.1 - 0.12 11.6 0.0 0.25 10.5 0.0 1.5 1 0 0 1 1 1 0 DNA recombination-mediator protein A Arf PF00025.21 KFM26524.1 - 3.3e-44 150.4 0.1 8.2e-41 139.4 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 KFM26524.1 - 1.5e-10 41.3 0.1 2.7e-10 40.5 0.1 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KFM26524.1 - 4.9e-07 29.3 0.0 6.6e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KFM26524.1 - 2.1e-06 27.5 0.0 3.1e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KFM26524.1 - 6.2e-06 26.3 0.1 9.4e-06 25.7 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Peptidase_M16 PF00675.20 KFM26524.1 - 6.3e-06 26.2 0.0 1.1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) G-alpha PF00503.20 KFM26524.1 - 2.7e-05 23.5 0.0 0.0025 17.0 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KFM26524.1 - 0.00035 20.0 0.0 0.00051 19.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 KFM26524.1 - 0.074 12.6 0.6 0.27 10.8 0.6 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B CBFD_NFYB_HMF PF00808.23 KFM26525.1 - 2.7e-13 50.0 0.5 5e-13 49.1 0.5 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SAGA-Tad1 PF12767.7 KFM26525.1 - 0.019 14.7 0.0 0.29 10.8 0.0 2.0 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit Histone PF00125.24 KFM26525.1 - 0.4 11.1 1.6 0.66 10.3 0.0 1.9 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Med3 PF11593.8 KFM26525.1 - 0.87 8.7 3.5 1.3 8.1 3.5 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Cytochrom_B561 PF03188.16 KFM26526.1 - 1.8e-34 118.8 1.1 2.7e-34 118.3 1.1 1.2 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 KFM26526.1 - 0.017 14.9 0.4 0.017 14.9 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) DUF4079 PF13301.6 KFM26526.1 - 0.36 11.0 9.0 3.7 7.7 7.9 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) Proteasome PF00227.26 KFM26528.1 - 1.3e-58 197.6 0.3 1.7e-58 197.2 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KFM26528.1 - 3.8e-14 52.1 0.1 6.9e-14 51.2 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Ribosomal_60s PF00428.19 KFM26528.1 - 0.01 16.4 7.5 0.031 14.8 7.5 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein NIF PF03031.18 KFM26529.1 - 1.1e-23 83.7 0.0 1.5e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT_2 PF16589.5 KFM26529.1 - 0.02 15.3 0.0 0.042 14.3 0.0 1.4 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KFM26529.1 - 0.042 14.1 0.0 0.08 13.2 0.0 1.4 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain PTCB-BRCT PF12738.7 KFM26529.1 - 0.054 13.4 0.0 0.092 12.7 0.0 1.4 1 0 0 1 1 1 0 twin BRCT domain Patatin PF01734.22 KFM26530.1 - 1.4e-27 97.2 0.4 6e-18 65.8 0.6 2.5 2 0 0 2 2 2 2 Patatin-like phospholipase fn3 PF00041.21 KFM26530.1 - 0.003 17.9 0.1 3.6 8.0 0.0 2.4 2 0 0 2 2 2 2 Fibronectin type III domain Patatin PF01734.22 KFM26531.1 - 1.2e-10 42.0 0.0 3.1e-10 40.6 0.0 1.7 1 1 0 1 1 1 1 Patatin-like phospholipase Patatin PF01734.22 KFM26532.1 - 3e-14 53.7 1.3 4.6e-13 49.8 1.3 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase Peptidase_S49 PF01343.18 KFM26533.1 - 4.2e-62 208.7 0.0 3.5e-37 127.7 0.0 2.4 2 0 0 2 2 2 2 Peptidase family S49 SDH_sah PF01972.16 KFM26533.1 - 0.00061 18.9 0.2 0.00091 18.3 0.2 1.2 1 0 0 1 1 1 1 Serine dehydrogenase proteinase CLP_protease PF00574.23 KFM26533.1 - 0.00071 19.5 0.1 0.0033 17.3 0.1 2.0 2 0 0 2 2 2 1 Clp protease ECH_1 PF00378.20 KFM26533.1 - 0.25 10.6 1.0 1.9 7.7 0.2 2.6 2 1 1 3 3 3 0 Enoyl-CoA hydratase/isomerase Pex14_N PF04695.13 KFM26535.1 - 0.064 13.9 0.2 0.37 11.5 0.1 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DASH_Spc34 PF08657.10 KFM26535.1 - 0.12 12.1 0.3 0.23 11.2 0.3 1.3 1 0 0 1 1 1 0 DASH complex subunit Spc34 NAD_binding_2 PF03446.15 KFM26536.1 - 8.7e-14 52.0 0.0 1.3e-13 51.5 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KFM26536.1 - 4e-11 43.2 0.0 7.1e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Kinesin PF00225.23 KFM26537.1 - 5.4e-64 216.2 0.0 7.9e-50 169.7 0.0 2.2 1 1 1 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 KFM26537.1 - 3.9e-06 26.9 0.0 7.2e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding Atg14 PF10186.9 KFM26537.1 - 0.0032 16.6 4.2 0.0058 15.8 4.2 1.3 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_13 PF13166.6 KFM26537.1 - 0.073 11.7 5.6 0.1 11.2 5.6 1.2 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.11 KFM26537.1 - 0.076 11.9 15.8 0.16 10.8 15.8 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein Fez1 PF06818.15 KFM26537.1 - 0.15 12.5 25.3 0.29 11.6 20.2 2.9 2 1 0 2 2 2 0 Fez1 DUF1993 PF09351.10 KFM26537.1 - 0.24 11.5 4.4 10 6.2 0.1 3.3 1 1 1 3 3 3 0 Domain of unknown function (DUF1993) IFT57 PF10498.9 KFM26537.1 - 0.64 8.9 4.9 1 8.2 4.9 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Exonuc_VII_L PF02601.15 KFM26537.1 - 2.1 7.8 9.8 5 6.6 9.8 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit Histone PF00125.24 KFM26538.1 - 1.3e-29 103.2 0.1 1.5e-29 103.0 0.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KFM26538.1 - 1.2e-05 25.4 0.0 1.3e-05 25.3 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KFM26538.1 - 3.5e-05 24.0 0.0 4.7e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 KFM26538.1 - 0.00028 21.2 0.0 0.00033 21.0 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CIA30 PF08547.12 KFM26539.1 - 1.4e-38 132.4 0.0 2.1e-38 131.9 0.0 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) AAA_25 PF13481.6 KFM26540.1 - 0.068 12.7 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KFM26540.1 - 0.15 12.3 0.0 1.1 9.6 0.0 2.4 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KFM26540.1 - 0.17 12.4 0.0 0.36 11.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DEAD PF00270.29 KFM26541.1 - 7e-45 152.9 0.0 1.2e-44 152.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM26541.1 - 7.3e-27 93.9 0.0 4.1e-26 91.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Oxidored_q6 PF01058.22 KFM26541.1 - 8.2e-21 74.2 0.1 1.6e-20 73.2 0.1 1.5 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit GUCT PF08152.12 KFM26541.1 - 9.4e-21 73.9 0.0 2.3e-20 72.7 0.0 1.7 1 0 0 1 1 1 1 GUCT (NUC152) domain ResIII PF04851.15 KFM26541.1 - 0.0031 17.5 0.0 0.0052 16.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KFM26541.1 - 0.048 13.0 1.8 0.095 12.0 0.0 2.2 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit PTR2 PF00854.21 KFM26542.1 - 2.2e-97 326.4 7.9 3.3e-97 325.8 7.9 1.2 1 0 0 1 1 1 1 POT family DUF1011 PF06237.12 KFM26542.1 - 6.4 7.2 10.2 8.4 6.8 0.2 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1011) Phostensin_N PF13916.6 KFM26543.1 - 0.036 14.4 0.9 0.059 13.7 0.9 1.3 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal Radical_SAM PF04055.21 KFM26545.1 - 4.8e-26 92.1 0.0 7.2e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.20 KFM26545.1 - 6.1e-20 71.1 0.0 1.1e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 KFM26545.1 - 9.7e-12 44.7 0.0 1.9e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 TRAM domain TRAM_2 PF18693.1 KFM26545.1 - 0.0046 17.1 0.0 0.019 15.1 0.0 2.0 1 1 0 1 1 1 1 TRAM domain Lipase_GDSL_2 PF13472.6 KFM26545.1 - 0.035 14.5 0.1 0.15 12.4 0.1 2.2 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family E1-E2_ATPase PF00122.20 KFM26547.1 - 1.2e-36 125.9 0.9 1.2e-36 125.9 0.9 2.9 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KFM26547.1 - 1.1e-18 68.3 2.6 2.7e-18 67.1 2.6 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 KFM26547.1 - 1.8e-17 63.7 0.2 1.8e-17 63.7 0.2 3.2 4 1 0 4 4 4 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KFM26547.1 - 1.3e-14 54.0 0.0 2.5e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KFM26547.1 - 1.2e-08 34.5 0.0 2.8e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KFM26547.1 - 1.5e-05 24.9 0.6 7.5e-05 22.6 0.6 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Deltameth_res PF16020.5 KFM26547.1 - 2.1 8.3 4.1 2.8 7.9 1.1 2.7 2 0 0 2 2 2 0 Deltamethrin resistance Cation_ATPase_C PF00689.21 KFM26548.1 - 8.3e-44 149.5 1.9 8.3e-44 149.5 1.9 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KFM26548.1 - 6.3e-38 130.1 0.3 6.3e-38 130.1 0.3 3.1 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 KFM26548.1 - 5.5e-19 69.3 0.0 9.9e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KFM26548.1 - 8.2e-09 35.0 0.0 3.2e-08 33.1 0.0 2.1 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KFM26548.1 - 3.3e-05 23.9 0.0 6.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KFM26548.1 - 4e-05 23.5 0.1 0.00023 21.0 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase FHA PF00498.26 KFM26549.1 - 1.7e-17 63.5 0.0 2.6e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KFM26549.1 - 1.7e-11 44.3 0.0 2.2e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Det1 PF09737.9 KFM26550.1 - 2.3e-09 36.8 0.0 9.8e-09 34.8 0.0 1.8 2 0 0 2 2 2 1 De-etiolated protein 1 Det1 TPD PF14811.6 KFM26552.1 - 2.9e-44 150.2 0.0 3.6e-44 149.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function TPD sequence-motif 2-Hacid_dh_C PF02826.19 KFM26553.1 - 7.7e-38 129.6 0.0 1.1e-37 129.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFM26553.1 - 2e-21 76.1 0.0 2.4e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 KFM26553.1 - 0.012 16.1 0.0 0.077 13.6 0.0 2.3 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 KFM26553.1 - 0.028 14.8 0.0 0.049 14.1 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding XdhC_C PF13478.6 KFM26553.1 - 0.032 14.7 0.1 0.18 12.3 0.0 2.2 2 0 0 2 2 2 0 XdhC Rossmann domain Pyr_redox PF00070.27 KFM26553.1 - 0.055 14.0 0.0 0.14 12.7 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KFM26553.1 - 0.074 13.1 0.0 0.46 10.6 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DEAD PF00270.29 KFM26554.1 - 5.3e-52 176.1 0.0 8.4e-52 175.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM26554.1 - 9.8e-28 96.7 0.0 4.3e-27 94.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM26554.1 - 1.8e-05 24.8 0.0 2.8e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KFM26554.1 - 0.053 12.9 0.1 0.13 11.6 0.0 1.6 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Hydrolase PF00702.26 KFM26555.1 - 2.8e-12 47.4 0.0 4.1e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFM26555.1 - 4.4e-12 46.8 0.0 6.4e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFM26555.1 - 0.0054 16.8 0.6 0.012 15.6 0.4 1.8 1 1 1 2 2 2 1 HAD-hyrolase-like Hydrolase_3 PF08282.12 KFM26555.1 - 0.0057 16.4 0.0 0.039 13.7 0.0 1.9 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KFM26555.1 - 0.079 13.0 0.0 7.8 6.5 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Adaptin_N PF01602.20 KFM26556.1 - 1e-80 271.8 0.0 1.4e-80 271.4 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KFM26556.1 - 1.2e-33 116.4 0.1 6.5e-30 104.3 0.0 3.1 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KFM26556.1 - 1.4e-05 25.3 17.6 0.034 14.5 0.2 5.2 3 3 2 6 6 6 4 HEAT repeats HEAT PF02985.22 KFM26556.1 - 0.0017 18.4 13.1 8.2 7.0 0.1 6.6 7 0 0 7 7 7 2 HEAT repeat DUF3602 PF12223.8 KFM26557.1 - 0.11 13.1 1.8 0.17 12.5 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3602) GAS PF13851.6 KFM26558.1 - 2.3 7.6 10.8 1 8.7 5.1 2.3 2 2 0 2 2 2 0 Growth-arrest specific micro-tubule binding HrpA_pilin PF09589.10 KFM26558.1 - 2.4 8.9 10.4 9.2 7.1 0.4 3.0 2 1 0 2 2 2 0 HrpA pilus formation protein Spc7 PF08317.11 KFM26558.1 - 3.6 6.4 12.8 0.33 9.8 3.5 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein Nop53 PF07767.11 KFM26559.1 - 6.6e-54 183.8 12.1 8.3e-54 183.5 12.1 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) ANAPC4_WD40 PF12894.7 KFM26560.1 - 9.6e-05 22.6 0.0 7.2 7.0 0.0 4.9 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFM26560.1 - 0.026 15.4 0.1 7.2 7.7 0.0 4.0 5 1 0 5 5 5 0 WD domain, G-beta repeat FliO PF04347.13 KFM26560.1 - 0.11 12.8 0.0 0.78 10.1 0.0 2.3 2 0 0 2 2 2 0 Flagellar biosynthesis protein, FliO DAO PF01266.24 KFM26561.1 - 8e-22 78.3 3.7 4.7e-20 72.5 0.0 2.0 1 1 1 2 2 2 2 FAD dependent oxidoreductase ThiF PF00899.21 KFM26561.1 - 0.027 13.8 0.1 0.058 12.7 0.1 1.4 1 0 0 1 1 1 0 ThiF family HI0933_like PF03486.14 KFM26561.1 - 0.092 11.4 0.2 0.35 9.5 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein DapB_N PF01113.20 KFM26561.1 - 0.2 11.8 0.4 0.33 11.1 0.4 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DAO PF01266.24 KFM26562.1 - 1.7e-43 149.6 1.0 1.9e-43 149.4 1.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFM26562.1 - 0.0027 17.0 0.1 0.044 13.0 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KFM26562.1 - 0.06 13.2 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 KFM26562.1 - 0.096 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Thi4 PF01946.17 KFM26562.1 - 0.15 11.3 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 KFM26562.1 - 0.24 10.1 0.0 8.2 5.0 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein MFS_1 PF07690.16 KFM26563.1 - 5.2e-31 107.8 50.2 3e-23 82.3 25.7 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily CBM_20 PF00686.19 KFM26564.1 - 1.2e-17 63.6 0.1 2e-17 62.8 0.1 1.4 1 0 0 1 1 1 1 Starch binding domain XRN_M PF17846.1 KFM26564.1 - 0.17 10.8 0.3 0.22 10.4 0.3 1.1 1 0 0 1 1 1 0 Xrn1 helical domain BPD_transp_1 PF00528.22 KFM26565.1 - 1.9e-18 66.8 10.5 1.9e-18 66.8 10.5 1.9 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component PET117 PF15786.5 KFM26565.1 - 0.4 11.0 2.5 0.43 10.9 0.0 2.1 2 0 0 2 2 2 0 PET assembly of cytochrome c oxidase, mitochondrial Peptidase_U4 PF03419.13 KFM26565.1 - 0.89 8.8 12.3 0.29 10.4 8.0 2.1 2 1 0 2 2 2 0 Sporulation factor SpoIIGA Diphthamide_syn PF01866.17 KFM26566.1 - 7.9e-107 357.2 0.0 9.9e-107 356.9 0.0 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein DUF1236 PF06823.12 KFM26566.1 - 0.083 12.8 0.5 0.21 11.5 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1236) Pyr_redox_2 PF07992.14 KFM26567.1 - 1.2e-09 37.9 0.5 6.9e-05 22.2 0.2 2.9 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KFM26567.1 - 3.6e-09 36.5 0.1 2e-06 27.4 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFM26567.1 - 4.7e-09 36.4 0.1 3.3e-08 33.6 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KFM26567.1 - 5.3e-08 33.3 0.0 0.0045 17.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KFM26567.1 - 1.2e-06 28.0 0.1 0.016 14.5 0.0 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 KFM26567.1 - 3.4e-06 26.5 0.0 0.00037 19.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFM26567.1 - 2e-05 23.8 0.0 0.00018 20.7 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain FMO-like PF00743.19 KFM26567.1 - 3.2e-05 22.6 0.2 0.002 16.6 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Thi4 PF01946.17 KFM26567.1 - 6.3e-05 22.3 0.1 0.0038 16.5 0.0 2.2 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KFM26567.1 - 0.00014 21.6 0.0 0.00033 20.3 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KFM26567.1 - 0.00057 18.7 0.6 0.001 17.9 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 KFM26567.1 - 0.0028 16.8 0.1 0.18 10.9 0.1 2.7 3 1 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_7 PF13241.6 KFM26567.1 - 0.0042 17.5 0.1 0.3 11.5 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 KFM26567.1 - 0.008 15.5 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.20 KFM26567.1 - 0.012 15.6 0.0 0.058 13.5 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Amino_oxidase PF01593.24 KFM26567.1 - 0.02 14.2 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase K_oxygenase PF13434.6 KFM26567.1 - 0.036 13.2 0.5 1 8.5 0.3 2.3 1 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 KFM26567.1 - 0.05 12.7 0.0 0.11 11.5 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein ELFV_dehydrog PF00208.21 KFM26567.1 - 0.077 12.7 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase CoA_binding_2 PF13380.6 KFM26568.1 - 0.18 12.3 3.1 5.8 7.4 0.8 2.7 3 0 0 3 3 3 0 CoA binding domain DUF1631 PF07793.11 KFM26569.1 - 1.5 7.1 6.3 3.2 6.1 6.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Zn_peptidase PF04228.13 KFM26570.1 - 0.12 11.8 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase PMSR PF01625.21 KFM26571.1 - 1.9e-50 171.0 1.4 2.2e-50 170.8 1.4 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase LRR_6 PF13516.6 KFM26572.1 - 2.6e-28 95.6 10.4 0.018 15.1 0.0 14.1 14 0 0 14 14 14 8 Leucine Rich repeat LRR_4 PF12799.7 KFM26572.1 - 7.7e-23 80.2 0.0 0.0016 18.8 0.1 9.7 5 3 6 11 11 11 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFM26572.1 - 2e-21 75.5 1.8 0.0012 18.5 0.2 7.6 3 2 7 10 10 10 9 Leucine rich repeat LRR_1 PF00560.33 KFM26572.1 - 0.00019 21.5 8.6 8.8 7.3 0.0 8.3 10 0 0 10 10 10 1 Leucine Rich Repeat LRR_9 PF14580.6 KFM26572.1 - 0.00047 19.7 0.0 3.5 7.1 0.0 4.3 2 1 2 5 5 5 1 Leucine-rich repeat ABC_tran PF00005.27 KFM26573.1 - 1.3e-32 113.2 0.0 2.1e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KFM26573.1 - 4.1e-24 85.7 3.6 2.6e-13 50.3 0.5 2.1 1 1 1 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KFM26573.1 - 1.7e-05 24.4 0.0 0.0003 20.3 0.0 1.8 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KFM26573.1 - 2.9e-05 24.5 2.9 3.7e-05 24.2 1.1 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 KFM26573.1 - 0.00016 21.4 0.3 0.44 10.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KFM26573.1 - 0.00019 21.7 0.1 0.0012 19.1 0.1 2.2 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.20 KFM26573.1 - 0.00061 19.7 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 KFM26573.1 - 0.002 18.3 0.2 0.028 14.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KFM26573.1 - 0.0021 17.9 0.2 1.4 8.6 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.9 KFM26573.1 - 0.0068 15.2 0.2 0.033 13.0 0.0 2.0 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_30 PF13604.6 KFM26573.1 - 0.0081 15.9 1.2 0.087 12.5 1.0 2.4 1 1 0 1 1 1 1 AAA domain MobB PF03205.14 KFM26573.1 - 0.0094 15.9 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B RsgA_GTPase PF03193.16 KFM26573.1 - 0.02 14.8 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 KFM26573.1 - 0.029 14.1 0.2 0.098 12.4 0.1 1.9 2 0 0 2 2 1 0 P-loop containing region of AAA domain SRP54 PF00448.22 KFM26573.1 - 0.045 13.4 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA PF00004.29 KFM26573.1 - 0.07 13.6 0.1 1.1 9.7 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DLIC PF05783.11 KFM26573.1 - 0.085 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) PEPCK_ATP PF01293.20 KFM26573.1 - 0.1 11.2 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase Zeta_toxin PF06414.12 KFM26573.1 - 0.12 11.7 0.9 0.43 9.8 0.0 2.2 3 0 0 3 3 3 0 Zeta toxin DUF87 PF01935.17 KFM26573.1 - 0.24 11.5 0.1 0.43 10.6 0.1 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain Clat_adaptor_s PF01217.20 KFM26574.1 - 8.4e-56 187.8 1.5 1e-55 187.6 1.5 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain MA3 PF02847.17 KFM26575.1 - 6.9e-75 248.3 0.0 2.6e-17 62.8 0.0 4.6 5 0 0 5 5 5 4 MA3 domain Acetyltransf_6 PF13480.7 KFM26575.1 - 5.8 7.1 10.4 0.85 9.8 1.4 3.8 4 1 0 4 4 4 0 Acetyltransferase (GNAT) domain TIP49 PF06068.13 KFM26577.1 - 3.1e-165 549.6 0.0 3.7e-165 549.3 0.0 1.0 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KFM26577.1 - 4.9e-16 58.6 0.0 1.3e-15 57.3 0.0 1.8 1 0 0 1 1 1 1 TIP49 AAA-lid domain RuvB_N PF05496.12 KFM26577.1 - 2.8e-11 43.4 0.1 3.6e-08 33.3 0.0 2.3 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 KFM26577.1 - 2.8e-10 40.7 0.1 2.2e-06 28.2 0.1 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFM26577.1 - 6.7e-07 29.7 0.3 0.041 14.2 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KFM26577.1 - 0.00015 22.2 3.5 0.00041 20.8 0.2 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.6 KFM26577.1 - 0.00029 21.1 0.1 0.00068 19.9 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFM26577.1 - 0.00032 21.0 2.6 0.0041 17.5 2.6 2.3 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KFM26577.1 - 0.00074 19.5 0.2 0.036 14.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KFM26577.1 - 0.00084 19.0 0.0 0.002 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 KFM26577.1 - 0.0021 17.8 0.1 1 9.0 0.1 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 KFM26577.1 - 0.0064 15.9 0.3 0.18 11.2 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF2075 PF09848.9 KFM26577.1 - 0.0078 15.5 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) TsaE PF02367.17 KFM26577.1 - 0.011 15.8 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KFM26577.1 - 0.014 15.3 0.1 0.026 14.5 0.1 1.4 1 0 0 1 1 1 0 NACHT domain DnaB_C PF03796.15 KFM26577.1 - 0.014 14.7 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_33 PF13671.6 KFM26577.1 - 0.023 14.9 0.1 0.11 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 KFM26577.1 - 0.023 14.7 0.1 0.6 10.1 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KFM26577.1 - 0.026 14.2 0.5 1.2 8.8 0.2 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KFM26577.1 - 0.073 13.6 0.1 0.25 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain GvpD PF07088.11 KFM26577.1 - 0.086 11.4 0.3 0.42 9.2 0.1 1.9 2 0 0 2 2 2 0 GvpD gas vesicle protein IstB_IS21 PF01695.17 KFM26577.1 - 0.089 12.5 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 KFM26577.1 - 0.095 12.7 0.0 9.6 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KFM26577.1 - 0.16 11.5 0.2 0.51 9.8 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region PCI PF01399.27 KFM26578.1 - 1.2e-09 38.7 0.0 2.2e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 PCI domain eIF3m_C_helix PF18005.1 KFM26578.1 - 0.08 12.7 2.6 0.081 12.6 0.5 2.1 2 0 0 2 2 2 0 eIF3 subunit M, C-terminal helix Paramyxo_NS_C PF02725.14 KFM26578.1 - 0.1 12.7 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Non-structural protein C TipAS PF07739.13 KFM26579.1 - 0.096 13.2 0.1 0.16 12.5 0.1 1.4 1 1 0 1 1 1 0 TipAS antibiotic-recognition domain LXG PF04740.12 KFM26579.1 - 0.11 12.2 0.1 0.15 11.8 0.1 1.1 1 0 0 1 1 1 0 LXG domain of WXG superfamily Matrilin_ccoil PF10393.9 KFM26580.1 - 0.036 13.9 0.7 0.11 12.4 0.0 2.2 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin ZapD PF07072.11 KFM26580.1 - 0.14 11.9 0.2 0.14 11.9 0.2 2.6 2 1 0 2 2 2 0 Cell division protein Prefoldin_2 PF01920.20 KFM26580.1 - 0.47 10.4 3.1 1.6 8.7 0.0 2.6 2 1 0 2 2 2 0 Prefoldin subunit DUF3209 PF11483.8 KFM26580.1 - 2 8.9 11.1 1.5 9.3 3.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3209) EF-hand_1 PF00036.32 KFM26582.1 - 7.2e-10 37.7 0.6 0.0078 15.7 0.0 4.2 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 KFM26582.1 - 1.6e-09 38.1 0.1 0.00017 21.9 0.0 3.2 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KFM26582.1 - 4.1e-08 32.5 0.2 0.0094 15.8 0.0 4.4 5 0 0 5 5 5 2 EF-hand domain EF-hand_5 PF13202.6 KFM26582.1 - 1.4e-07 30.6 3.7 0.0032 16.9 0.0 3.2 4 0 0 4 4 4 2 EF hand tRNA-synt_2 PF00152.20 KFM26583.1 - 4.9e-103 344.5 0.0 5.8e-103 344.3 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KFM26583.1 - 1.9e-12 47.0 0.0 3.3e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain GAD PF02938.14 KFM26583.1 - 1.6e-10 41.1 0.0 2.6e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 GAD domain tRNA-synt_2d PF01409.20 KFM26583.1 - 0.00085 18.9 0.0 1.3 8.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) TPR_10 PF13374.6 KFM26584.1 - 3.7e-12 45.7 5.3 0.00015 21.5 0.3 4.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFM26584.1 - 4.2e-11 43.0 9.0 2e-09 37.6 0.1 4.3 3 1 2 5 5 5 3 Tetratricopeptide repeat UVR PF02151.19 KFM26584.1 - 6.8e-06 25.7 14.0 0.0072 16.0 3.2 2.5 2 0 0 2 2 2 2 UvrB/uvrC motif HisG_C PF08029.11 KFM26586.1 - 3.1e-15 56.1 0.0 6e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain HisG PF01634.18 KFM26586.1 - 1.6e-14 54.2 0.0 2.8e-09 37.2 0.0 2.2 2 0 0 2 2 2 2 ATP phosphoribosyltransferase DNA_pol_A_exo1 PF01612.20 KFM26587.1 - 4.2e-41 140.6 0.0 6e-41 140.1 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease Aminotran_1_2 PF00155.21 KFM26587.1 - 4.2e-16 59.1 0.0 2.3e-15 56.7 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class I and II HRDC PF00570.23 KFM26587.1 - 1.1e-10 41.3 0.1 1.1e-10 41.3 0.1 2.4 2 0 0 2 2 2 1 HRDC domain Ysc84 PF04366.12 KFM26588.1 - 3.7e-09 36.4 0.0 6.7e-09 35.6 0.0 1.6 1 1 0 1 1 1 1 Las17-binding protein actin regulator Macro PF01661.21 KFM26589.1 - 1.6e-39 134.6 0.0 2e-39 134.3 0.0 1.1 1 0 0 1 1 1 1 Macro domain Ysc84 PF04366.12 KFM26590.1 - 1.2e-15 57.4 0.1 1.6e-15 57.0 0.1 1.2 1 0 0 1 1 1 1 Las17-binding protein actin regulator DUF4231 PF14015.6 KFM26591.1 - 0.045 14.2 0.8 2.3 8.7 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Aa_trans PF01490.18 KFM26592.1 - 1.5e-68 231.4 15.2 1.8e-68 231.1 15.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Paramecium_SA PF01508.16 KFM26592.1 - 0.13 12.7 0.7 0.21 12.0 0.7 1.2 1 0 0 1 1 1 0 Paramecium surface antigen domain FAD_binding_7 PF03441.14 KFM26594.1 - 1.6e-60 204.1 0.2 2.4e-60 203.5 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KFM26594.1 - 1.6e-39 135.6 0.2 2.7e-39 134.8 0.2 1.4 1 0 0 1 1 1 1 DNA photolyase Prefoldin_2 PF01920.20 KFM26595.1 - 5.9e-21 74.4 2.6 6.6e-21 74.3 2.6 1.0 1 0 0 1 1 1 1 Prefoldin subunit Med9 PF07544.13 KFM26595.1 - 0.042 13.9 1.4 0.2 11.8 0.1 2.1 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 FAM76 PF16046.5 KFM26595.1 - 0.043 13.2 1.6 0.056 12.8 1.6 1.1 1 0 0 1 1 1 0 FAM76 protein NPV_P10 PF05531.12 KFM26595.1 - 0.043 14.3 0.9 0.064 13.7 0.3 1.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein YabA PF06156.13 KFM26595.1 - 0.043 14.4 4.7 0.29 11.8 3.9 2.0 1 1 1 2 2 2 0 Initiation control protein YabA LPP PF04728.13 KFM26595.1 - 0.1 13.0 3.1 0.15 12.5 0.2 2.3 2 1 1 3 3 3 0 Lipoprotein leucine-zipper PCRF PF03462.18 KFM26595.1 - 0.22 11.4 4.6 0.41 10.5 4.6 1.5 1 1 0 1 1 1 0 PCRF domain DASH_Dad4 PF08650.10 KFM26595.1 - 0.33 10.9 3.0 0.24 11.4 1.0 1.8 2 1 0 2 2 2 0 DASH complex subunit Dad4 PEARLI-4 PF05278.12 KFM26595.1 - 0.39 10.3 5.0 4.8 6.7 5.0 1.9 1 1 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Spc24 PF08286.11 KFM26595.1 - 0.73 10.1 8.1 44 4.4 8.1 2.1 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Aminotran_1_2 PF00155.21 KFM26596.1 - 1.2e-29 103.6 0.0 1.8e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 KFM26596.1 - 2.8e-05 23.2 0.0 4.1e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Allinase Cys_Met_Meta_PP PF01053.20 KFM26596.1 - 0.091 11.3 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme WD40 PF00400.32 KFM26597.1 - 2e-24 85.4 7.6 6.4e-09 36.3 0.0 9.4 9 0 0 9 9 9 5 WD domain, G-beta repeat Utp21 PF04192.12 KFM26597.1 - 3e-20 72.7 0.0 2.4e-13 50.1 0.0 2.2 2 0 0 2 2 2 2 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 KFM26597.1 - 1.1e-10 41.7 0.0 0.26 11.6 0.0 7.3 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 KFM26597.1 - 0.0082 15.9 0.0 4.1 7.1 0.0 4.3 5 1 1 6 6 6 1 TUP1-like enhancer of split Cytochrom_D1 PF02239.16 KFM26597.1 - 0.14 10.7 0.0 0.51 8.8 0.0 2.0 2 0 0 2 2 2 0 Cytochrome D1 heme domain Nup160 PF11715.8 KFM26597.1 - 0.16 10.6 0.5 9.2 4.8 0.0 2.6 2 1 1 3 3 3 0 Nucleoporin Nup120/160 zf-CCCH PF00642.24 KFM26598.1 - 0.00041 20.2 0.4 0.00063 19.6 0.4 1.2 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFM26598.1 - 0.0013 18.7 0.3 0.0019 18.2 0.3 1.2 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KFM26599.1 - 1.2e-05 25.1 9.7 8.8e-05 22.3 5.7 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KFM26599.1 - 1.5 8.7 12.6 1.2 9.0 6.2 2.5 3 0 0 3 3 3 0 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KFM26599.1 - 3.9 8.1 14.0 17 6.0 0.4 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger SET PF00856.28 KFM26600.1 - 1.5e-13 51.5 0.0 7e-13 49.3 0.0 1.8 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.16 KFM26600.1 - 3.6e-09 37.2 0.3 3.6e-09 37.2 0.3 2.1 4 0 0 4 4 4 1 Pre-SET motif ABC2_membrane PF01061.24 KFM26601.1 - 8e-81 270.5 63.4 1.8e-48 164.8 31.8 2.9 4 0 0 4 4 2 2 ABC-2 type transporter ABC_tran PF00005.27 KFM26601.1 - 7.2e-38 130.2 0.0 7.5e-20 71.8 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KFM26601.1 - 1.8e-09 37.8 0.0 0.061 13.1 0.0 3.3 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KFM26601.1 - 3.5e-08 33.3 0.4 0.0042 16.7 0.1 2.6 2 0 0 2 2 2 2 AAA domain PDR_assoc PF08370.11 KFM26601.1 - 1.1e-07 31.5 0.3 1.1e-07 31.5 0.3 3.3 3 0 0 3 3 2 1 Plant PDR ABC transporter associated AAA_16 PF13191.6 KFM26601.1 - 1.8e-07 31.7 0.1 0.0038 17.6 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KFM26601.1 - 1.5e-06 27.8 1.2 0.031 14.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFM26601.1 - 4.4e-06 26.7 0.1 0.016 15.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA PF00004.29 KFM26601.1 - 1.3e-05 25.7 0.2 0.0051 17.2 0.0 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KFM26601.1 - 2e-05 24.8 0.1 0.13 12.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KFM26601.1 - 4e-05 24.2 0.0 0.14 12.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.6 KFM26601.1 - 4.1e-05 23.9 0.1 0.13 12.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KFM26601.1 - 4.6e-05 23.2 1.9 0.2 11.3 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.6 KFM26601.1 - 7.3e-05 23.1 2.4 0.28 11.4 0.1 2.7 2 0 0 2 2 2 2 AAA domain ABC_trans_N PF14510.6 KFM26601.1 - 0.00027 21.5 0.0 0.00053 20.5 0.0 1.5 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_23 PF13476.6 KFM26601.1 - 0.00027 21.5 0.9 0.78 10.2 0.1 2.3 2 0 0 2 2 2 2 AAA domain cobW PF02492.19 KFM26601.1 - 0.00028 20.5 3.1 0.086 12.4 0.2 2.7 3 0 0 3 3 3 2 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KFM26601.1 - 0.0013 18.7 1.4 0.23 11.4 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.6 KFM26601.1 - 0.0016 18.2 0.2 0.31 10.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 KFM26601.1 - 0.0026 17.7 0.0 0.19 11.6 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain PduV-EutP PF10662.9 KFM26601.1 - 0.003 17.3 0.9 2.7 7.8 0.1 2.5 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation SMC_N PF02463.19 KFM26601.1 - 0.0062 16.0 0.0 31 3.9 0.0 3.8 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KFM26601.1 - 0.0065 16.6 0.3 3.3 7.8 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase NTPase_1 PF03266.15 KFM26601.1 - 0.012 15.5 1.6 5.8 6.8 0.1 3.2 3 0 0 3 3 3 0 NTPase RNA_helicase PF00910.22 KFM26601.1 - 0.014 15.8 0.1 4.8 7.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_19 PF13245.6 KFM26601.1 - 0.028 14.8 1.0 0.25 11.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KFM26601.1 - 0.03 14.3 2.5 0.35 10.9 0.1 2.7 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 KFM26601.1 - 0.033 13.5 0.2 8.7 5.6 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin SRP54 PF00448.22 KFM26601.1 - 0.042 13.5 0.6 5.3 6.6 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain RuvB_N PF05496.12 KFM26601.1 - 0.051 13.3 0.8 5 6.8 0.2 2.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 KFM26601.1 - 0.053 13.5 0.9 13 5.8 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KFM26601.1 - 0.058 13.4 0.1 2.8 8.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 KFM26601.1 - 0.073 12.3 0.0 5.9 6.1 0.0 2.6 3 0 0 3 3 3 0 Septin AAA_17 PF13207.6 KFM26601.1 - 0.088 13.2 2.6 1.1 9.7 0.1 2.7 3 0 0 3 3 2 0 AAA domain Roc PF08477.13 KFM26601.1 - 0.1 12.8 0.3 16 5.7 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 KFM26601.1 - 0.12 11.9 0.2 8.7 5.9 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B PDR_CDR PF06422.12 KFM26601.1 - 0.12 12.3 0.1 0.12 12.3 0.1 3.7 4 0 0 4 4 2 0 CDR ABC transporter MobB PF03205.14 KFM26601.1 - 0.17 11.8 0.6 20 5.1 0.1 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Mg_chelatase PF01078.21 KFM26601.1 - 0.51 9.7 1.7 2.2 7.6 0.2 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DIOX_N PF14226.6 KFM26602.1 - 0.015 16.1 0.0 0.023 15.5 0.0 1.3 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KFM26602.1 - 0.13 12.7 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Aminotran_1_2 PF00155.21 KFM26604.1 - 7.8e-67 226.0 0.0 9e-67 225.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KFM26604.1 - 0.0021 17.4 0.1 0.0021 17.4 0.1 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KFM26604.1 - 0.063 12.2 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Leo1 PF04004.13 KFM26606.1 - 2.3e-39 134.9 0.0 3.2e-39 134.4 0.0 1.2 1 0 0 1 1 1 1 Leo1-like protein PET117 PF15786.5 KFM26606.1 - 0.017 15.4 0.2 0.033 14.4 0.2 1.4 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial zf-CHCC PF10276.9 KFM26607.1 - 0.0017 18.4 0.1 0.0047 17.0 0.1 1.7 2 0 0 2 2 2 1 Zinc-finger domain PCI PF01399.27 KFM26608.1 - 0.0024 18.3 0.0 0.0074 16.8 0.0 1.9 2 0 0 2 2 2 1 PCI domain PUMA PF15826.5 KFM26609.1 - 0.0055 16.9 3.9 0.006 16.8 3.9 1.0 1 0 0 1 1 1 1 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis Rhomboid PF01694.22 KFM26610.1 - 3.2e-27 95.4 13.2 4.5e-27 94.9 13.2 1.2 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 KFM26610.1 - 0.091 13.3 0.8 0.22 12.1 0.2 2.1 1 1 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) Gly_transf_sug PF04488.15 KFM26611.1 - 4.4e-09 36.9 0.0 8.3e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 KFM26611.1 - 0.27 10.5 0.0 0.73 9.1 0.1 1.5 1 1 1 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Mg_trans_NIPA PF05653.14 KFM26614.1 - 3.5e-18 65.7 12.8 4.7e-18 65.3 12.8 1.2 1 0 0 1 1 1 1 Magnesium transporter NIPA MSP1_C PF07462.11 KFM26615.1 - 3.7 6.2 3.2 5.1 5.7 3.2 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus LZ_Tnp_IS66 PF13007.7 KFM26616.1 - 0.99 10.2 7.3 0.44 11.4 0.2 2.4 2 1 0 2 2 2 0 Transposase C of IS166 homeodomain WD40 PF00400.32 KFM26617.1 - 4.3e-36 122.3 18.5 5e-05 24.0 0.1 11.1 11 0 0 11 11 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM26617.1 - 5.5e-15 55.4 0.2 0.00065 20.0 0.0 5.7 6 1 1 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFM26617.1 - 0.17 10.5 0.9 0.41 9.2 0.0 2.0 4 0 0 4 4 4 0 Nucleoporin Nup120/160 RRM_1 PF00076.22 KFM26618.1 - 1.7e-16 59.8 0.0 1.5e-09 37.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFM26618.1 - 0.23 11.6 0.0 0.88 9.7 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif PHM7_cyt PF14703.6 KFM26618.1 - 0.26 11.5 0.4 18 5.5 0.0 2.8 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter WW PF00397.26 KFM26619.1 - 2.7e-10 40.1 1.8 4.1e-10 39.6 1.8 1.3 1 0 0 1 1 1 1 WW domain EspB PF05802.11 KFM26619.1 - 0.045 13.7 0.0 0.045 13.7 0.0 1.1 1 0 0 1 1 1 0 Enterobacterial EspB protein CDC73_C PF05179.14 KFM26620.1 - 1.8e-38 131.7 0.0 2.4e-38 131.3 0.0 1.2 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N PF16050.5 KFM26620.1 - 2.1e-19 70.0 0.0 5.4e-15 55.5 0.0 2.2 2 0 0 2 2 2 2 Paf1 complex subunit CDC73 N-terminal DUF1138 PF06592.13 KFM26621.1 - 5e-06 26.5 0.1 8.4e-06 25.8 0.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1138) NAD_binding_5 PF07994.12 KFM26622.1 - 1.2e-116 389.6 0.0 1.3e-116 389.5 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 KFM26622.1 - 7.5e-46 154.9 0.0 1.1e-45 154.3 0.0 1.3 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase TrmE_N PF10396.9 KFM26622.1 - 0.17 12.3 0.0 1.9 8.9 0.0 2.1 2 0 0 2 2 2 0 GTP-binding protein TrmE N-terminus NAD_binding_5 PF07994.12 KFM26623.1 - 2.8e-07 30.2 3.7 2.8e-07 30.2 3.7 1.4 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase Asp-B-Hydro_N PF05279.11 KFM26624.1 - 0.18 11.9 24.5 0.23 11.5 24.5 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region LMBR1 PF04791.16 KFM26624.1 - 0.52 9.2 1.1 0.66 8.8 1.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein TFIIA PF03153.13 KFM26624.1 - 0.54 10.2 9.1 0.64 9.9 9.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SWI-SNF_Ssr4 PF08549.10 KFM26624.1 - 2.6 6.6 15.7 4.2 5.9 15.7 1.3 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Hamartin PF04388.12 KFM26624.1 - 3.3 6.2 7.7 4.3 5.9 7.7 1.1 1 0 0 1 1 1 0 Hamartin protein V_ATPase_I PF01496.19 KFM26624.1 - 3.6 5.4 8.9 4.8 5.0 8.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family BAF1_ABF1 PF04684.13 KFM26624.1 - 8.7 5.3 11.3 11 4.9 11.3 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Pan3_PK PF18101.1 KFM26625.1 - 3.9e-32 111.1 0.0 5.5e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 Pan3 Pseudokinase domain DSPn PF14671.6 KFM26627.1 - 1.8e-23 83.5 0.0 1.7e-21 77.1 0.0 2.1 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 KFM26627.1 - 1.3e-12 47.7 0.0 1.9e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFM26627.1 - 1.5e-05 25.1 0.0 2.3e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 KFM26627.1 - 0.00046 19.8 0.0 0.00068 19.3 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFM26627.1 - 0.014 15.4 0.4 0.022 14.7 0.4 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Amidase PF01425.21 KFM26628.1 - 3e-81 273.7 0.6 2.4e-70 237.8 1.4 2.2 2 0 0 2 2 2 2 Amidase RRM_1 PF00076.22 KFM26628.1 - 6.7e-11 41.8 0.0 1.3e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 KFM26628.1 - 6.8e-08 33.2 0.0 1.3e-07 32.3 0.0 1.4 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 KFM26628.1 - 2.3e-06 27.4 2.7 6.6e-06 26.0 2.7 1.8 1 0 0 1 1 1 1 Zinc finger domain RRM_3 PF08777.11 KFM26628.1 - 0.006 16.6 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 RNA binding motif zf-CCCH_4 PF18044.1 KFM26628.1 - 0.0077 16.0 1.9 0.016 15.0 1.9 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_3 PF15663.5 KFM26628.1 - 0.039 14.2 0.1 0.039 14.2 0.1 1.7 2 0 0 2 2 2 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 KFM26628.1 - 0.09 13.3 4.9 0.053 14.0 1.7 2.3 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH PF00642.24 KFM26628.1 - 0.22 11.5 6.1 0.031 14.2 1.3 2.1 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Aminotran_3 PF00202.21 KFM26629.1 - 7.5e-62 209.3 0.2 1.3e-61 208.5 0.2 1.2 1 1 0 1 1 1 1 Aminotransferase class-III JmjC PF02373.22 KFM26630.1 - 2e-34 118.4 0.0 2.6e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 JmjC domain, hydroxylase Bin3 PF06859.12 KFM26631.1 - 8.5e-17 61.8 0.0 2.2e-14 54.0 0.0 2.2 1 1 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_23 PF13489.6 KFM26631.1 - 5.9e-06 26.2 0.0 8.9e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM26631.1 - 6.1e-06 26.9 0.2 0.00067 20.3 0.1 2.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFM26631.1 - 1.5e-05 25.5 0.3 0.00037 21.1 0.3 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM26631.1 - 1.7e-05 25.5 0.0 3.9e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM26631.1 - 1.9e-05 24.5 0.0 0.00013 21.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 KFM26631.1 - 0.00039 20.4 0.0 0.00053 19.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KFM26631.1 - 0.011 15.2 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 KFM26631.1 - 0.028 13.9 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.14 KFM26631.1 - 0.13 11.8 0.1 0.24 10.9 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain HIT PF01230.23 KFM26632.1 - 4.7e-23 81.8 0.1 7.9e-23 81.0 0.1 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KFM26632.1 - 0.0026 18.2 0.0 0.004 17.6 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Methyltransf_25 PF13649.6 KFM26634.1 - 4.6e-05 24.1 0.1 0.00027 21.6 0.0 2.2 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM26634.1 - 0.00014 22.5 0.0 0.00034 21.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM26634.1 - 0.01 15.7 0.0 0.025 14.4 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KFM26634.1 - 0.014 16.0 0.0 0.11 13.2 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 KFM26634.1 - 0.085 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain zf-C3HC4_2 PF13923.6 KFM26635.1 - 4.1e-09 36.1 8.3 4.1e-09 36.1 8.3 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM26635.1 - 1.4e-07 31.3 16.9 1.6e-06 27.8 7.4 3.1 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM26635.1 - 1.8e-06 28.1 7.2 1.8e-06 28.1 7.2 3.5 3 1 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 KFM26635.1 - 2.3e-06 27.5 4.1 2.3e-06 27.5 4.1 3.5 2 2 1 3 3 3 2 RING-type zinc-finger ZZ PF00569.17 KFM26635.1 - 2.3e-06 27.3 4.6 6.8e-06 25.8 4.6 1.8 1 0 0 1 1 1 1 Zinc finger, ZZ type zf-C3HC4_4 PF15227.6 KFM26635.1 - 8.9e-06 25.8 10.9 8.9e-06 25.8 10.9 3.1 3 1 0 3 3 3 2 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KFM26635.1 - 2.7e-05 23.9 5.4 2.7e-05 23.9 5.4 3.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM26635.1 - 0.0021 18.0 7.8 0.0021 18.0 7.8 3.9 4 1 0 4 4 4 2 zinc-RING finger domain zf-Nse PF11789.8 KFM26635.1 - 0.0072 16.1 3.9 0.0072 16.1 3.9 2.2 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit DUF1180 PF06679.12 KFM26635.1 - 4 7.8 8.9 1.1 9.7 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Redoxin PF08534.10 KFM26636.1 - 6.5e-33 113.5 0.0 7.4e-33 113.3 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KFM26636.1 - 1.3e-09 38.0 0.0 1.5e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Snf7 PF03357.21 KFM26637.1 - 5.7e-21 74.9 4.3 7.2e-21 74.5 4.3 1.2 1 0 0 1 1 1 1 Snf7 Sigma70_r4 PF04545.16 KFM26637.1 - 0.035 13.6 0.1 0.095 12.2 0.1 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 DUF3138 PF11336.8 KFM26637.1 - 0.55 8.8 17.7 0.079 11.6 13.8 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) CENP-Q PF13094.6 KFM26637.1 - 7.2 6.8 9.2 3 8.0 0.3 2.8 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit MoaC PF01967.21 KFM26638.1 - 1.9e-46 157.5 0.6 2.1e-46 157.4 0.6 1.0 1 0 0 1 1 1 1 MoaC family PDDEXK_6 PF04720.12 KFM26639.1 - 3.4e-16 59.9 0.0 4.3e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 PDDEXK-like family of unknown function DAO PF01266.24 KFM26640.1 - 1.3e-62 212.5 4.8 1.4e-62 212.3 4.8 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFM26640.1 - 4.6e-07 30.0 0.3 1.2e-06 28.7 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 KFM26640.1 - 0.00014 21.2 0.1 0.00022 20.6 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 KFM26640.1 - 0.00027 20.3 0.0 0.00057 19.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KFM26640.1 - 0.0005 19.2 1.2 0.0062 15.6 0.7 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 KFM26640.1 - 0.00077 18.8 1.2 0.004 16.5 0.8 2.0 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KFM26640.1 - 0.0011 18.3 0.2 0.0021 17.4 0.2 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KFM26640.1 - 0.0011 18.2 5.4 0.0028 16.8 5.4 1.7 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KFM26640.1 - 0.0013 17.5 1.1 0.0024 16.7 1.1 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KFM26640.1 - 0.032 14.8 1.2 0.15 12.6 0.5 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KFM26640.1 - 0.035 14.4 0.1 0.063 13.5 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 KFM26640.1 - 0.035 14.0 1.1 0.06 13.2 0.5 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 KFM26640.1 - 0.037 13.3 0.9 0.054 12.7 0.9 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KFM26640.1 - 0.047 13.0 0.1 0.064 12.5 0.1 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase ApbA PF02558.16 KFM26640.1 - 0.055 13.1 0.2 0.094 12.4 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.7 KFM26640.1 - 0.057 12.8 0.6 0.085 12.2 0.6 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_2 PF03446.15 KFM26640.1 - 0.082 13.1 0.2 0.94 9.6 0.0 2.1 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.14 KFM26640.1 - 0.18 11.4 0.4 0.32 10.6 0.4 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Rhomboid PF01694.22 KFM26641.1 - 4.8e-36 124.0 8.8 6e-36 123.7 8.8 1.1 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 KFM26641.1 - 0.044 14.4 0.0 0.086 13.4 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) PGI PF00342.19 KFM26642.1 - 2.5e-154 514.5 0.0 3e-154 514.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase ERGIC_N PF13850.6 KFM26643.1 - 3e-24 85.2 0.0 5.8e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) COPIIcoated_ERV PF07970.12 KFM26643.1 - 4.2e-22 79.1 0.0 7.2e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter Thioredoxin PF00085.20 KFM26643.1 - 3.3e-19 68.8 0.0 6.3e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 KFM26643.1 - 3.6e-05 23.3 0.0 8.4e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family LytR_C PF13399.6 KFM26643.1 - 0.0039 18.2 0.0 0.011 16.6 0.0 1.8 1 0 0 1 1 1 1 LytR cell envelope-related transcriptional attenuator Thioredoxin_2 PF13098.6 KFM26643.1 - 0.092 13.2 0.1 0.19 12.2 0.1 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain TFX_C PF14601.6 KFM26643.1 - 0.096 12.7 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 DNA_binding protein, TFX, C-term RRM_1 PF00076.22 KFM26644.1 - 1.2e-14 53.9 0.0 2.4e-07 30.4 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GYF_2 PF14237.6 KFM26644.1 - 6.8e-14 51.4 0.5 1.7e-13 50.2 0.5 1.7 1 0 0 1 1 1 1 GYF domain 2 GYF PF02213.16 KFM26644.1 - 1.7e-07 30.8 0.5 3.6e-07 29.7 0.5 1.6 1 0 0 1 1 1 1 GYF domain RRM_7 PF16367.5 KFM26644.1 - 0.0049 17.0 0.0 0.0094 16.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif RRM_1 PF00076.22 KFM26645.1 - 4.8e-23 80.8 0.0 1.6e-10 40.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFM26645.1 - 2.4e-09 36.8 0.0 1.1e-05 25.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFM26645.1 - 1.1e-06 28.4 0.0 0.00048 19.9 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif Abhydrolase_8 PF06259.12 KFM26645.1 - 0.0089 15.7 0.1 0.021 14.5 0.1 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase Nup35_RRM_2 PF14605.6 KFM26645.1 - 0.036 14.1 0.0 0.36 10.9 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif CinA PF02464.17 KFM26645.1 - 0.088 12.4 0.1 0.2 11.2 0.1 1.6 1 0 0 1 1 1 0 Competence-damaged protein CoaE PF01121.20 KFM26647.1 - 2.2e-27 95.9 0.1 1.5e-14 54.1 0.0 2.1 1 1 1 2 2 2 2 Dephospho-CoA kinase DUF2474 PF10617.9 KFM26647.1 - 0.022 14.6 1.1 0.064 13.1 1.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2474) AAA_33 PF13671.6 KFM26647.1 - 0.032 14.4 0.0 0.037 14.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KFM26647.1 - 0.068 13.4 0.0 0.1 12.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain CbiX PF01903.17 KFM26647.1 - 0.12 12.7 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 CbiX AAA_18 PF13238.6 KFM26647.1 - 0.12 12.9 0.0 0.15 12.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain SMI1_KNR4 PF09346.10 KFM26648.1 - 0.075 13.4 0.0 0.12 12.7 0.0 1.4 1 1 0 1 1 1 0 SMI1 / KNR4 family (SUKH-1) RNA_pol_Rpb1_1 PF04997.12 KFM26649.1 - 1.6e-84 283.9 0.0 2.2e-84 283.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KFM26649.1 - 9.9e-84 280.9 0.3 1.5e-83 280.3 0.0 1.4 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KFM26649.1 - 6.7e-72 241.1 0.0 1.1e-71 240.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KFM26649.1 - 8.5e-32 110.3 0.0 1.4e-31 109.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KFM26649.1 - 1.2e-28 99.2 0.0 2.3e-28 98.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DZR PF12773.7 KFM26649.1 - 9.2 6.4 7.5 22 5.2 2.9 2.8 2 1 1 3 3 3 0 Double zinc ribbon Gcn1_N PF12074.8 KFM26650.1 - 0.013 14.9 1.0 2.8 7.1 0.2 2.9 2 1 1 3 3 3 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal DUF1990 PF09348.10 KFM26651.1 - 7.9e-38 129.9 0.1 9.3e-38 129.7 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1990) MRP-S28 PF10213.9 KFM26652.1 - 7.4e-11 42.6 0.0 1.4e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein HTH_53 PF18606.1 KFM26652.1 - 0.0022 17.6 0.1 0.019 14.6 0.0 2.5 2 1 1 3 3 3 1 Zap helix turn helix N-terminal domain Ldh_1_C PF02866.18 KFM26655.1 - 4.4e-42 143.8 0.0 8.1e-42 143.0 0.0 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KFM26655.1 - 4.1e-40 137.1 0.5 1.1e-39 135.8 0.5 1.7 1 1 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 KFM26655.1 - 0.0053 17.2 0.6 0.089 13.2 0.0 2.3 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KFM26655.1 - 0.043 12.8 0.0 0.14 11.1 0.0 1.7 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Rad21_Rec8_N PF04825.13 KFM26656.1 - 1.4e-10 41.4 0.0 2.1e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein ADH_N PF08240.12 KFM26657.1 - 1.4e-23 82.8 3.2 1.4e-23 82.8 3.2 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFM26657.1 - 1.1e-20 73.9 0.0 2.1e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFM26657.1 - 0.00048 21.2 0.0 0.0009 20.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 KFM26657.1 - 0.00052 20.2 0.0 0.00094 19.4 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.21 KFM26657.1 - 0.0023 17.3 0.8 0.0044 16.3 0.5 1.7 1 1 1 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain PALP PF00291.25 KFM26657.1 - 0.0068 15.9 0.2 0.011 15.2 0.2 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme 2-Hacid_dh_C PF02826.19 KFM26657.1 - 0.01 15.2 0.1 0.018 14.4 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KFM26657.1 - 0.014 16.0 0.0 0.036 14.6 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 KFM26657.1 - 0.047 13.9 0.1 0.098 12.9 0.1 1.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 KFM26657.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Met_10 PF02475.16 KFM26657.1 - 0.13 12.0 0.0 0.43 10.3 0.0 1.7 2 0 0 2 2 2 0 Met-10+ like-protein Flg_hook PF02120.16 KFM26657.1 - 0.19 11.6 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK GATase_2 PF00310.21 KFM26658.1 - 1.5e-177 590.6 0.0 1.9e-177 590.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 KFM26658.1 - 3.5e-153 510.1 1.6 2.7e-151 503.9 0.2 2.2 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 KFM26658.1 - 4.6e-106 354.4 0.0 3e-105 351.7 0.0 2.0 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 KFM26658.1 - 1.3e-77 259.7 2.2 3.1e-77 258.5 2.2 1.7 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 KFM26658.1 - 3.3e-27 95.5 0.4 1.1e-26 93.8 0.4 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 KFM26658.1 - 2.6e-20 72.3 0.0 5.5e-20 71.2 0.0 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 KFM26658.1 - 1.9e-09 37.6 0.1 9.5e-09 35.4 0.1 2.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KFM26658.1 - 2.8e-06 27.8 0.6 0.0014 19.2 0.1 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KFM26658.1 - 2.8e-06 26.9 0.8 6e-06 25.9 0.8 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KFM26658.1 - 3.4e-06 26.6 0.0 6.2e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KFM26658.1 - 3.8e-06 26.4 0.9 0.028 13.7 0.1 3.7 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFM26658.1 - 3.3e-05 23.6 2.0 0.0027 17.4 0.5 2.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KFM26658.1 - 3.7e-05 22.6 0.3 3.7e-05 22.6 0.3 1.6 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 KFM26658.1 - 3.8e-05 22.9 0.2 3.8e-05 22.9 0.2 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KFM26658.1 - 0.00044 19.5 2.6 0.0018 17.4 0.2 2.9 3 0 0 3 3 3 1 FAD binding domain NAD_binding_7 PF13241.6 KFM26658.1 - 0.00098 19.5 0.1 0.82 10.1 0.1 2.6 2 0 0 2 2 2 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 KFM26658.1 - 0.0015 17.9 1.0 0.31 10.3 0.1 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 KFM26658.1 - 0.0023 17.2 0.1 0.0045 16.3 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain FMO-like PF00743.19 KFM26658.1 - 0.034 12.6 0.0 0.59 8.5 0.0 2.4 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like Thi4 PF01946.17 KFM26658.1 - 0.042 13.1 0.1 0.14 11.4 0.1 1.9 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 KFM26658.1 - 0.13 11.3 0.1 0.33 9.9 0.1 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein AdoHcyase_NAD PF00670.21 KFM26658.1 - 0.2 11.7 1.7 1.6 8.7 0.1 2.6 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KFM26658.1 - 0.22 10.9 0.3 3.3 7.0 0.1 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FMN_dh PF01070.18 KFM26658.1 - 2.6 7.0 9.2 0.72 8.8 0.9 3.0 3 0 0 3 3 3 0 FMN-dependent dehydrogenase Macoilin PF09726.9 KFM26659.1 - 1.1 7.8 5.9 1.3 7.5 5.9 1.0 1 0 0 1 1 1 0 Macoilin family BACK PF07707.15 KFM26661.1 - 8.2e-05 22.6 0.0 0.00015 21.8 0.0 1.3 1 0 0 1 1 1 1 BTB And C-terminal Kelch F5_F8_type_C PF00754.25 KFM26661.1 - 0.00055 20.0 0.0 0.0028 17.8 0.0 2.1 1 1 1 2 2 2 1 F5/8 type C domain Methyltransf_FA PF12248.8 KFM26661.1 - 0.00066 20.0 0.0 0.0011 19.2 0.0 1.4 1 0 0 1 1 1 1 Farnesoic acid 0-methyl transferase DAD PF02109.16 KFM26662.1 - 8.6e-33 112.9 1.3 1e-32 112.7 1.3 1.0 1 0 0 1 1 1 1 DAD family DNA_primase_S PF01896.19 KFM26664.1 - 6.3e-50 169.7 0.0 8.4e-50 169.3 0.0 1.2 1 0 0 1 1 1 1 DNA primase small subunit NTP_transferase PF00483.23 KFM26665.1 - 7.6e-53 179.6 0.0 1.1e-52 179.1 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KFM26665.1 - 6.4e-12 46.1 0.0 8.7e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 KFM26665.1 - 5.5e-09 35.4 14.6 2.7e-07 30.0 2.1 3.9 2 1 3 5 5 5 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KFM26665.1 - 0.00011 21.9 6.1 0.00029 20.5 3.2 3.1 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.19 KFM26665.1 - 0.0045 16.9 0.0 0.0067 16.4 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase DUF4954 PF16314.5 KFM26665.1 - 0.053 11.7 0.6 0.087 10.9 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) IspD PF01128.19 KFM26665.1 - 0.16 11.7 0.0 0.43 10.3 0.0 1.7 2 0 0 2 2 2 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase PROCN PF08083.11 KFM26666.1 - 8.1e-220 729.6 14.3 7.2e-118 393.8 1.9 3.2 3 0 0 3 3 3 3 PROCN (NUC071) domain PRP8_domainIV PF12134.8 KFM26666.1 - 1e-126 421.2 0.3 1.5e-126 420.6 0.3 1.3 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 KFM26666.1 - 1.2e-88 295.1 1.7 3.2e-88 293.7 1.7 1.8 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 KFM26666.1 - 5e-86 286.3 4.3 5.8e-86 286.1 3.0 1.8 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 KFM26666.1 - 1.2e-72 242.2 0.0 2.3e-72 241.4 0.0 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 KFM26666.1 - 3.8e-50 168.9 0.0 7.7e-50 167.9 0.0 1.5 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.9 KFM26666.1 - 1.8e-46 156.4 0.3 4.2e-46 155.2 0.3 1.7 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 Hom_end_hint PF05203.16 KFM26666.1 - 2.1e-12 47.5 0.0 1e-11 45.3 0.0 2.1 2 0 0 2 2 2 1 Hom_end-associated Hint JAB PF01398.21 KFM26666.1 - 1.7e-06 28.0 0.0 4.1e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Hint PF01079.20 KFM26666.1 - 0.019 14.5 0.0 0.05 13.1 0.0 1.7 1 0 0 1 1 1 0 Hint module NTP_transf_2 PF01909.23 KFM26667.1 - 0.00068 19.9 0.0 0.0011 19.3 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KFM26667.1 - 0.23 11.6 0.0 0.4 10.8 0.0 1.3 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase WD40 PF00400.32 KFM26668.1 - 2.9e-43 145.0 36.8 7.9e-06 26.5 0.2 14.1 14 0 0 14 14 14 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM26668.1 - 5.6e-17 61.8 1.2 0.0083 16.4 0.0 8.2 3 2 5 9 9 9 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFM26668.1 - 1.2e-06 27.8 0.2 0.6 9.0 0.0 4.4 4 1 1 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein APAF1_C PF17908.1 KFM26668.1 - 2.3e-06 27.7 0.0 3.5e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 APAF-1 helical domain Nup160 PF11715.8 KFM26668.1 - 6.9e-05 21.7 5.8 0.46 9.1 0.0 5.9 5 1 1 6 6 6 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KFM26668.1 - 0.00035 19.4 0.0 15 4.1 0.0 5.3 4 1 1 6 6 6 2 Nup133 N terminal like Cytochrom_D1 PF02239.16 KFM26668.1 - 0.022 13.3 0.3 3.4 6.1 0.1 2.6 3 0 0 3 3 3 0 Cytochrome D1 heme domain PQQ_3 PF13570.6 KFM26668.1 - 0.24 11.9 0.1 0.24 11.9 0.1 9.8 9 1 1 10 10 10 0 PQQ-like domain zf-rbx1 PF12678.7 KFM26669.1 - 3.1e-22 78.6 2.8 5.6e-22 77.8 2.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KFM26669.1 - 9.5e-15 54.4 5.6 1.4e-14 53.9 5.6 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 KFM26669.1 - 4.3e-10 39.3 3.7 2.1e-08 33.8 1.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM26669.1 - 5.7e-10 39.4 8.2 3.6e-09 36.8 7.2 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KFM26669.1 - 2.7e-08 33.5 0.3 7.3e-08 32.2 0.3 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFM26669.1 - 1.9e-07 31.0 0.3 4.5e-07 29.8 0.1 1.8 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KFM26669.1 - 1.9e-06 27.6 4.1 4e-06 26.6 0.8 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KFM26669.1 - 4.8e-06 26.4 2.1 1.3e-05 25.0 2.1 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFM26669.1 - 2.7e-05 23.9 3.1 0.00025 20.8 0.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFM26669.1 - 0.0003 20.4 5.6 0.00057 19.6 0.3 2.8 2 1 1 3 3 3 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 KFM26669.1 - 0.00076 19.1 3.4 0.00076 19.1 3.4 2.2 2 1 1 3 3 3 1 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 KFM26669.1 - 0.0022 18.1 5.3 0.0034 17.5 1.1 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 KFM26669.1 - 0.0051 16.6 0.1 0.01 15.6 0.1 1.5 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.11 KFM26669.1 - 0.011 16.0 1.5 0.011 16.0 1.5 1.8 2 0 0 2 2 2 0 RING-like domain zinc_ribbon_16 PF17034.5 KFM26669.1 - 0.032 14.4 4.2 0.14 12.3 4.2 1.9 1 1 0 1 1 1 0 Zinc-ribbon like family Rtf2 PF04641.12 KFM26669.1 - 0.044 13.1 0.0 0.044 13.1 0.0 2.0 2 1 0 2 2 2 0 Rtf2 RING-finger DUF2318 PF10080.9 KFM26669.1 - 0.044 13.9 0.5 6.9 6.8 0.1 2.4 2 1 0 2 2 2 0 Predicted membrane protein (DUF2318) RINGv PF12906.7 KFM26669.1 - 0.045 13.9 2.1 0.045 13.9 2.1 2.3 2 0 0 2 2 2 0 RING-variant domain zf-RING_10 PF16685.5 KFM26669.1 - 0.054 13.6 0.5 0.88 9.8 0.1 2.2 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-C3H2C3 PF17122.5 KFM26669.1 - 0.076 13.1 2.3 0.076 13.1 2.3 2.2 2 1 0 2 2 2 0 Zinc-finger TerY_C PF15616.6 KFM26669.1 - 0.16 12.0 1.6 0.17 12.0 0.2 1.6 1 1 0 1 1 1 0 TerY-C metal binding domain Baculo_RING PF05883.11 KFM26669.1 - 0.18 11.8 0.4 17 5.4 0.1 2.1 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain DiS_P_DiS PF06750.13 KFM26669.1 - 0.23 11.6 2.3 12 6.1 0.2 2.1 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain FANCL_C PF11793.8 KFM26669.1 - 0.38 11.0 7.3 3.2 8.0 7.3 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain HAD_2 PF13419.6 KFM26670.1 - 7.1e-15 55.5 0.0 9.4e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFM26670.1 - 0.00043 20.6 0.0 0.00087 19.6 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase O-FucT PF10250.9 KFM26671.1 - 4e-11 43.2 0.0 1.5e-08 34.7 0.0 2.7 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase EMP24_GP25L PF01105.24 KFM26672.1 - 7.3e-18 65.1 0.0 1.1e-17 64.5 0.0 1.3 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Noelin-1 PF12308.8 KFM26672.1 - 0.16 11.9 0.2 0.28 11.2 0.2 1.3 1 0 0 1 1 1 0 Neurogenesis glycoprotein TPR_19 PF14559.6 KFM26675.1 - 3.8e-17 62.6 37.5 1.7e-08 34.8 0.6 7.8 6 2 2 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 KFM26675.1 - 2.1e-13 50.7 23.6 3.3e-09 37.3 4.5 8.7 5 3 5 10 10 9 6 Tetratricopeptide repeat TPR_2 PF07719.17 KFM26675.1 - 1.7e-12 46.4 31.9 0.00071 19.5 0.1 10.0 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFM26675.1 - 2.7e-12 46.2 9.2 0.0038 16.9 0.0 7.0 6 1 1 7 7 7 3 TPR repeat TPR_1 PF00515.28 KFM26675.1 - 3.4e-11 42.5 7.4 6.5e-05 22.6 0.0 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFM26675.1 - 2.3e-10 40.6 36.5 0.0011 19.3 0.5 7.3 7 1 0 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 KFM26675.1 - 4.9e-10 39.1 11.7 0.0043 17.3 0.0 8.5 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFM26675.1 - 7.2e-08 32.6 60.2 0.0029 18.3 0.6 11.9 8 2 5 13 13 12 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM26675.1 - 2.2e-06 27.8 2.0 0.014 15.6 0.1 3.5 2 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KFM26675.1 - 6.9e-05 22.8 4.8 0.58 10.5 0.0 6.0 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFM26675.1 - 0.0022 17.9 17.5 1.3 9.2 0.1 7.4 8 0 0 8 8 8 2 Tetratricopeptide repeat MIT PF04212.18 KFM26675.1 - 0.014 15.4 3.6 0.56 10.3 0.2 4.5 4 1 1 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 KFM26675.1 - 0.37 11.5 0.0 0.37 11.5 0.0 6.6 8 0 0 8 8 6 0 Tetratricopeptide repeat GTP_EFTU PF00009.27 KFM26676.1 - 2.6e-52 177.2 0.0 4.1e-52 176.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KFM26676.1 - 8.5e-17 61.0 0.0 1.9e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KFM26676.1 - 2.8e-09 37.2 0.0 8.1e-09 35.8 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFM26676.1 - 9.8e-08 32.1 0.5 1.9e-07 31.2 0.5 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 KFM26676.1 - 0.00096 18.5 0.1 0.0017 17.7 0.1 1.3 1 0 0 1 1 1 1 Septin PduV-EutP PF10662.9 KFM26676.1 - 0.0048 16.7 0.0 1.9 8.2 0.0 2.6 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation EFG_II PF14492.6 KFM26676.1 - 0.0063 16.6 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II Roc PF08477.13 KFM26676.1 - 0.0093 16.2 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 KFM26676.1 - 0.045 13.3 0.4 0.8 9.2 0.7 2.9 2 1 0 2 2 2 0 Ferrous iron transport protein B SRPRB PF09439.10 KFM26676.1 - 0.11 11.9 0.0 0.57 9.6 0.0 2.1 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Arf PF00025.21 KFM26676.1 - 0.12 11.8 0.0 0.41 10.1 0.0 1.9 1 1 0 1 1 1 0 ADP-ribosylation factor family Dynamin_N PF00350.23 KFM26676.1 - 0.14 12.2 0.0 4.2 7.4 0.1 2.1 1 1 1 2 2 2 0 Dynamin family Met_10 PF02475.16 KFM26677.1 - 1.3e-63 214.4 0.0 1.5e-63 214.1 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Mg-por_mtran_C PF07109.11 KFM26677.1 - 0.032 14.6 0.0 0.09 13.1 0.0 1.8 2 0 0 2 2 2 0 Magnesium-protoporphyrin IX methyltransferase C-terminus Cons_hypoth95 PF03602.15 KFM26677.1 - 0.17 11.5 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Pep3_Vps18 PF05131.14 KFM26678.1 - 1.9e-16 60.3 0.0 3.6e-16 59.3 0.0 1.5 1 1 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 KFM26678.1 - 0.0091 15.9 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Region in Clathrin and VPS Aldose_epim PF01263.20 KFM26679.1 - 8.1e-33 114.0 0.0 1e-32 113.6 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase RETICULATA-like PF11891.8 KFM26681.1 - 2e-56 190.6 0.0 2.6e-56 190.3 0.0 1.1 1 0 0 1 1 1 1 Protein RETICULATA-related S4 PF01479.25 KFM26682.1 - 0.0032 17.2 0.0 1.6 8.5 0.0 2.5 2 0 0 2 2 2 2 S4 domain SH2 PF00017.24 KFM26682.1 - 0.024 14.8 0.0 0.062 13.4 0.0 1.7 1 0 0 1 1 1 0 SH2 domain LUC7 PF03194.15 KFM26683.1 - 1.1e-54 185.8 8.7 1.4e-54 185.5 8.7 1.1 1 0 0 1 1 1 1 LUC7 N_terminus Spectrin PF00435.21 KFM26683.1 - 0.028 14.9 5.1 2.1 8.8 2.7 2.5 2 0 0 2 2 2 0 Spectrin repeat FapA PF03961.13 KFM26683.1 - 0.041 12.5 0.6 0.056 12.0 0.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A zf-HIT PF04438.16 KFM26684.1 - 9.1e-08 31.8 11.7 1.4e-07 31.3 11.7 1.3 1 0 0 1 1 1 1 HIT zinc finger C5HCH PF17982.1 KFM26684.1 - 0.87 9.8 8.7 1.6 9.0 8.7 1.4 1 0 0 1 1 1 0 NSD Cys-His rich domain Hydrolase_like PF13242.6 KFM26685.1 - 2.2e-16 59.7 0.1 4.6e-16 58.6 0.1 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 KFM26685.1 - 8.4e-11 41.9 0.0 1.4e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase bZIP_1 PF00170.21 KFM26686.1 - 5.1e-11 42.5 3.4 7.5e-11 42.0 3.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFM26686.1 - 9.6e-05 22.4 3.9 0.00042 20.3 3.9 1.9 1 1 0 1 1 1 1 Basic region leucine zipper CENP-F_leu_zip PF10473.9 KFM26686.1 - 0.018 15.1 0.5 0.029 14.4 0.5 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_Maf PF03131.17 KFM26686.1 - 0.086 13.4 3.6 0.15 12.6 3.6 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor Autophagy_N PF03986.13 KFM26687.1 - 4.8e-41 139.9 0.0 6.4e-41 139.5 0.0 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 KFM26687.1 - 2.2e-18 66.6 0.1 2.2e-18 66.6 0.1 1.7 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 KFM26687.1 - 2.3e-14 52.6 1.6 4.7e-14 51.6 1.6 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal p450 PF00067.22 KFM26688.1 - 8.7e-33 113.8 0.0 1.2e-32 113.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFM26689.1 - 2.6e-23 82.5 0.0 2e-14 53.2 0.1 2.0 1 1 1 2 2 2 2 Cytochrome P450 Nnf1 PF03980.14 KFM26689.1 - 0.093 13.1 0.1 0.16 12.3 0.1 1.4 1 0 0 1 1 1 0 Nnf1 Rhodanese PF00581.20 KFM26690.1 - 1e-11 45.3 0.0 4.1e-11 43.3 0.0 1.9 1 1 0 1 1 1 1 Rhodanese-like domain RRM_1 PF00076.22 KFM26692.1 - 1.1e-05 25.2 0.0 0.00015 21.5 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ArfGap PF01412.18 KFM26693.1 - 3.3e-35 120.7 0.0 4.7e-35 120.2 0.0 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf ENTH PF01417.20 KFM26693.1 - 2.1e-29 102.1 0.0 2.8e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 ENTH domain Ins134_P3_kin PF05770.11 KFM26694.1 - 0.00016 21.3 0.2 0.31 10.5 0.0 2.2 1 1 1 2 2 2 2 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain Ins134_P3_kin_N PF17927.1 KFM26694.1 - 0.0041 17.5 0.0 0.0065 16.9 0.0 1.3 1 0 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain DUF697 PF05128.12 KFM26695.1 - 0.1 12.3 0.8 2.7 7.7 0.3 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF697) HSP20 PF00011.21 KFM26696.1 - 1.1e-22 80.1 1.1 1.3e-22 79.9 1.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KFM26696.1 - 2e-10 40.1 0.0 3e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA FKBP26_C PF18046.1 KFM26696.1 - 0.00028 20.9 0.3 0.037 14.1 0.2 2.2 2 0 0 2 2 2 2 FKBP26_C-terminal GvpH PF05455.11 KFM26696.1 - 0.038 14.1 0.1 0.051 13.6 0.1 1.2 1 0 0 1 1 1 0 GvpH DNA_pol3_beta_3 PF02768.15 KFM26696.1 - 0.077 12.8 0.0 0.3 10.9 0.0 1.8 2 0 0 2 2 2 0 DNA polymerase III beta subunit, C-terminal domain Ammonium_transp PF00909.21 KFM26697.1 - 9e-83 278.2 17.7 7.1e-55 186.3 7.9 2.0 1 1 1 2 2 2 2 Ammonium Transporter Family PhosphMutase PF10143.9 KFM26698.1 - 3.6e-42 144.1 0.0 9.7e-42 142.7 0.0 1.7 1 1 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Metalloenzyme PF01676.18 KFM26698.1 - 1e-23 84.0 0.0 1.7e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Phos_pyr_kin PF08543.12 KFM26698.1 - 6.7e-13 48.6 0.0 1.1e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 KFM26698.1 - 1e-05 25.0 0.1 2.4e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 pfkB family carbohydrate kinase Phosphodiest PF01663.22 KFM26698.1 - 0.00023 20.8 0.0 0.0022 17.6 0.0 2.0 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase LPP PF04728.13 KFM26700.1 - 0.036 14.4 1.6 0.32 11.4 0.4 2.3 2 0 0 2 2 2 0 Lipoprotein leucine-zipper PaREP1 PF05942.11 KFM26700.1 - 0.067 13.1 2.7 0.098 12.6 2.7 1.2 1 0 0 1 1 1 0 Archaeal PaREP1/PaREP8 family BBL5 PF07289.11 KFM26700.1 - 0.067 12.2 0.5 0.072 12.1 0.5 1.1 1 0 0 1 1 1 0 Bardet-Biedl syndrome 5 protein Bystin PF05291.11 KFM26700.1 - 0.072 12.4 0.3 0.083 12.2 0.3 1.1 1 0 0 1 1 1 0 Bystin Spore_III_AB PF09548.10 KFM26700.1 - 0.11 12.7 1.5 0.13 12.4 1.5 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Occludin_ELL PF07303.13 KFM26701.1 - 0.026 15.2 1.3 0.07 13.9 1.3 1.7 1 1 0 1 1 1 0 Occludin homology domain PI3K_P85_iSH2 PF16454.5 KFM26701.1 - 0.041 13.5 0.9 0.063 12.9 0.9 1.2 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain LSM PF01423.22 KFM26702.1 - 3e-21 74.9 0.0 3.6e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KFM26702.1 - 0.11 12.1 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Hfq protein SM-ATX PF14438.6 KFM26702.1 - 0.13 12.4 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain CIA30 PF08547.12 KFM26703.1 - 8.3e-42 142.9 0.0 9.7e-42 142.7 0.0 1.0 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Tli4_C PF18426.1 KFM26703.1 - 0.042 14.1 0.0 0.057 13.7 0.0 1.2 1 0 0 1 1 1 0 Tle cognate immunity protein 4 C-terminal domain Chorein_N PF12624.7 KFM26704.1 - 1.7e-21 76.5 0.0 2.8e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 VPS13 PF16908.5 KFM26704.1 - 2.6e-11 43.8 0.0 4.1e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal Cys_Met_Meta_PP PF01053.20 KFM26705.1 - 1.8e-50 171.6 0.0 2.8e-50 170.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme VPS13_C PF16909.5 KFM26705.1 - 3e-26 92.3 0.0 5.7e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 KFM26705.1 - 1.8e-23 83.3 0.0 2.4e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 SHR-binding domain of vacuolar-sorting associated protein 13 Aminotran_5 PF00266.19 KFM26705.1 - 4.6e-05 22.5 0.0 7e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KFM26705.1 - 8e-05 22.0 0.0 0.00013 21.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.11 KFM26705.1 - 0.22 10.0 0.0 0.34 9.4 0.0 1.1 1 0 0 1 1 1 0 Methionine gamma-lyase EF-1_beta_acid PF10587.9 KFM26705.1 - 0.66 10.5 2.4 2.2 8.8 2.4 1.9 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Ribosomal_S6e PF01092.19 KFM26706.1 - 1.8e-54 183.0 0.0 3.9e-54 181.9 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S6e JmjC PF02373.22 KFM26708.1 - 8.2e-41 139.0 0.0 1.2e-40 138.5 0.0 1.3 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-C5HC2 PF02928.16 KFM26708.1 - 7.6e-06 26.2 1.3 1.5e-05 25.2 1.3 1.6 1 0 0 1 1 1 1 C5HC2 zinc finger JmjN PF02375.17 KFM26708.1 - 0.0012 18.8 0.0 0.0024 17.8 0.0 1.5 1 0 0 1 1 1 1 jmjN domain ATP-synt_ab PF00006.25 KFM26709.1 - 0.0028 17.3 0.3 0.6 9.7 0.1 2.9 2 1 1 3 3 3 2 ATP synthase alpha/beta family, nucleotide-binding domain RRM_1 PF00076.22 KFM26710.1 - 1.6e-51 172.0 0.0 3.7e-17 61.9 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFM26710.1 - 6.4e-11 42.2 0.0 0.0095 16.0 0.0 3.2 3 0 0 3 3 3 3 RNA binding motif RRM_5 PF13893.6 KFM26710.1 - 2.7e-05 23.7 0.0 0.0097 15.5 0.0 2.3 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFM26710.1 - 0.00035 20.4 0.0 0.015 15.1 0.0 2.5 2 0 0 2 2 2 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KFM26710.1 - 0.0047 16.9 0.0 1.3 9.1 0.0 3.3 3 1 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 KFM26710.1 - 0.007 16.4 0.6 16 5.7 0.1 3.5 3 1 0 3 3 3 2 Limkain b1 Cas9_Topo PF17894.1 KFM26710.1 - 0.018 15.1 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 Topo homolgy domain in CRISPR-associated endonuclease Cas9 DbpA PF03880.15 KFM26710.1 - 0.034 14.1 0.0 21 5.2 0.0 3.1 3 0 0 3 3 3 0 DbpA RNA binding domain RRM_7 PF16367.5 KFM26710.1 - 0.036 14.2 0.1 1.9 8.6 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif Dynamin_N PF00350.23 KFM26711.1 - 7e-23 81.5 0.0 4.8e-10 39.7 0.0 2.4 1 1 1 2 2 2 2 Dynamin family MMR_HSR1 PF01926.23 KFM26711.1 - 2.5e-13 50.1 0.0 5.4e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase TMP-TENI PF02581.17 KFM26711.1 - 6.3e-13 48.5 0.2 1.4e-12 47.3 0.2 1.5 1 0 0 1 1 1 1 Thiamine monophosphate synthase RsgA_GTPase PF03193.16 KFM26711.1 - 1.9e-05 24.6 0.0 0.019 14.9 0.0 2.6 3 0 0 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 KFM26711.1 - 6e-05 22.7 0.0 0.0004 20.0 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 KFM26711.1 - 0.00013 21.4 0.1 0.0022 17.4 0.1 2.4 1 1 0 1 1 1 1 AIG1 family FeoB_N PF02421.18 KFM26711.1 - 0.0027 17.3 0.1 1 8.9 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B PduV-EutP PF10662.9 KFM26711.1 - 0.072 12.8 0.0 1.2 8.8 0.0 2.6 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DGCR6 PF07324.11 KFM26711.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 DiGeorge syndrome critical region 6 (DGCR6) protein Septin PF00735.18 KFM26711.1 - 0.16 11.2 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Septin CAAD PF14159.6 KFM26712.1 - 1.5e-30 104.9 0.0 1.8e-30 104.6 0.0 1.1 1 0 0 1 1 1 1 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase PLAC8 PF04749.17 KFM26714.1 - 1.8e-18 67.4 19.6 2.6e-18 66.8 19.6 1.3 1 0 0 1 1 1 1 PLAC8 family DUF3682 PF12446.8 KFM26714.1 - 0.0038 17.7 7.4 0.0084 16.6 7.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3682) U-box PF04564.15 KFM26715.1 - 3e-13 49.7 0.0 6.4e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 KFM26715.1 - 1.8e-06 27.7 0.0 3.6e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 KFM26715.1 - 0.0094 16.0 0.0 0.024 14.6 0.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger ATP-synt_10 PF05176.14 KFM26716.1 - 9.3e-07 28.3 0.0 9.9e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 ATP10 protein TetR_C_31 PF17940.1 KFM26718.1 - 0.023 14.9 0.4 0.026 14.7 0.4 1.1 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain PolyA_pol_RNAbd PF12627.7 KFM26719.1 - 0.12 12.2 0.4 0.27 11.0 0.1 1.8 2 0 0 2 2 2 0 Probable RNA and SrmB- binding site of polymerase A UCH PF00443.29 KFM26720.1 - 2.9e-47 161.3 0.0 3.8e-47 160.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFM26720.1 - 6.5e-14 52.3 0.0 1.3e-13 51.3 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 KFM26720.1 - 0.00023 20.9 0.0 0.00054 19.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Peptidase_C98 PF15499.6 KFM26720.1 - 0.024 14.1 0.0 0.16 11.4 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase PolyA_pol PF01743.20 KFM26721.1 - 4.5e-30 104.7 0.0 6.1e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 Poly A polymerase head domain ADH_zinc_N_2 PF13602.6 KFM26721.1 - 0.14 13.2 0.0 0.34 12.0 0.0 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase DHHC PF01529.20 KFM26722.1 - 1.4e-24 86.7 0.4 1.4e-24 86.7 0.4 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase OrfB_Zn_ribbon PF07282.11 KFM26723.1 - 0.0027 17.6 2.3 2.1 8.4 0.1 2.7 2 0 0 2 2 2 2 Putative transposase DNA-binding domain OTT_1508_deam PF14441.6 KFM26723.1 - 0.17 11.9 15.1 0.36 10.9 0.8 3.0 3 0 0 3 3 3 0 OTT_1508-like deaminase Cytochrome_C554 PF13435.6 KFM26723.1 - 0.32 11.9 6.9 9.2 7.3 0.7 2.5 2 0 0 2 2 2 0 Cytochrome c554 and c-prime HTS PF04204.16 KFM26723.1 - 0.41 9.5 1.7 6.5 5.6 0.1 2.2 2 0 0 2 2 2 0 Homoserine O-succinyltransferase PSI_PsaH PF03244.14 KFM26724.1 - 2.5e-30 104.8 0.0 4.1e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 Photosystem I reaction centre subunit VI Suc_Fer-like PF06999.12 KFM26724.1 - 7.6e-30 104.2 0.0 1.1e-29 103.7 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like PALP PF00291.25 KFM26725.1 - 8.6e-28 97.6 0.6 1.6e-27 96.7 0.6 1.4 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme FAM176 PF14851.6 KFM26726.1 - 0.0037 16.9 0.7 1.9 8.1 0.0 2.4 2 0 0 2 2 2 2 FAM176 family RELT PF12606.8 KFM26726.1 - 0.018 14.0 0.1 0.051 12.6 0.1 1.7 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 DUF2508 PF10704.9 KFM26726.1 - 0.056 13.6 0.1 1.4 9.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) RuvC PF02075.17 KFM26726.1 - 0.12 12.3 0.2 13 5.6 0.0 2.4 3 0 0 3 3 3 0 Crossover junction endodeoxyribonuclease RuvC RELT PF12606.8 KFM26727.1 - 0.097 11.7 0.0 0.34 9.9 0.0 1.9 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 Metallophos PF00149.28 KFM26728.1 - 5.6e-17 62.9 3.7 6.2e-09 36.6 1.2 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 KFM26728.1 - 5.4e-08 33.6 0.1 1.4e-07 32.2 0.1 1.8 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.7 KFM26728.1 - 2.4e-05 24.6 0.5 0.17 12.1 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Pur_ac_phosph_N PF16656.5 KFM26728.1 - 0.01 16.4 0.0 0.023 15.3 0.0 1.6 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain PTH2 PF01981.16 KFM26729.1 - 7e-20 71.5 0.2 8e-20 71.3 0.2 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Ribonucleas_3_3 PF14622.6 KFM26729.1 - 0.13 12.5 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease-III-like Ribosomal_L28 PF00830.19 KFM26730.1 - 1.3e-20 73.3 0.1 2.2e-20 72.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal L28 family Glyco_hydro_85 PF03644.13 KFM26730.1 - 0.076 12.4 0.0 0.082 12.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 UDPGP PF01704.18 KFM26731.1 - 2.4e-83 280.1 0.0 3.1e-83 279.7 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Trypsin_2 PF13365.6 KFM26732.1 - 9.8e-34 117.4 3.1 1.7e-33 116.6 3.1 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 KFM26732.1 - 5.5e-15 55.5 0.1 1.3e-14 54.3 0.1 1.7 1 0 0 1 1 1 1 PDZ domain Trypsin PF00089.26 KFM26732.1 - 1.1e-14 54.8 0.2 2.1e-14 53.9 0.2 1.4 1 1 0 1 1 1 1 Trypsin PDZ_6 PF17820.1 KFM26732.1 - 1e-05 25.3 1.7 0.024 14.5 0.1 3.5 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 KFM26732.1 - 0.035 14.4 0.4 0.73 10.2 0.3 2.8 2 1 0 2 2 2 0 PDZ domain Peptidase_S29 PF02907.15 KFM26732.1 - 0.089 12.5 0.2 0.26 11.0 0.1 1.8 2 0 0 2 2 2 0 Hepatitis C virus NS3 protease Peptidase_S46 PF10459.9 KFM26732.1 - 0.11 11.1 1.6 0.18 10.4 0.5 1.7 2 0 0 2 2 2 0 Peptidase S46 Myb_DNA-binding PF00249.31 KFM26733.1 - 1.1e-32 112.0 9.7 2.7e-15 56.3 1.0 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFM26733.1 - 8e-29 99.7 8.7 5.6e-17 61.7 0.2 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 KFM26733.1 - 0.063 13.3 0.0 0.74 9.9 0.0 2.1 1 1 1 2 2 2 0 SLIDE TPR_12 PF13424.6 KFM26734.1 - 1e-06 28.9 0.9 1e-06 28.9 0.9 2.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFM26734.1 - 0.13 12.4 1.8 0.23 11.7 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Abhydrolase_3 PF07859.13 KFM26735.1 - 7.2e-14 52.2 0.1 1.6e-13 51.0 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFM26735.1 - 3.2e-10 39.9 0.2 3.8e-07 29.8 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KFM26735.1 - 2.6e-07 30.2 0.3 0.017 14.4 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 COesterase PF00135.28 KFM26735.1 - 9.9e-07 28.0 0.4 1.4e-06 27.5 0.4 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_1 PF00561.20 KFM26735.1 - 2.5e-05 24.1 0.1 0.0037 16.9 0.2 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 KFM26735.1 - 0.0089 15.6 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 KFM26735.1 - 0.067 13.0 0.0 0.15 11.8 0.0 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase TPR_19 PF14559.6 KFM26740.1 - 3.5e-13 49.9 17.6 3.4e-06 27.5 4.5 4.0 1 1 2 4 4 4 4 Tetratricopeptide repeat FHA PF00498.26 KFM26740.1 - 4e-12 46.3 0.0 7.2e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 FHA domain TPR_14 PF13428.6 KFM26740.1 - 6.3e-09 35.9 37.0 0.079 13.8 0.1 8.0 3 2 5 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.17 KFM26740.1 - 1.8e-07 30.7 16.9 0.65 10.3 0.7 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat Yop-YscD_cpl PF16697.5 KFM26740.1 - 1.5e-06 28.4 0.0 4.7e-06 26.8 0.0 1.8 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain TPR_17 PF13431.6 KFM26740.1 - 2.9e-06 27.2 2.9 0.51 10.8 0.8 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFM26740.1 - 1.5e-05 24.8 0.6 27 5.3 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_15 PF13429.6 KFM26740.1 - 0.0012 18.1 9.0 1.4 8.1 0.3 3.3 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFM26740.1 - 0.0016 18.7 0.2 0.0016 18.7 0.2 5.3 3 2 3 6 6 6 3 Tetratricopeptide repeat Coatomer_E PF04733.14 KFM26740.1 - 0.0021 17.5 0.4 0.039 13.3 0.1 2.2 1 1 1 2 2 2 1 Coatomer epsilon subunit TPR_1 PF00515.28 KFM26740.1 - 0.0025 17.6 2.2 1.9 8.4 0.0 4.5 6 0 0 6 6 6 1 Tetratricopeptide repeat STAS_2 PF13466.6 KFM26740.1 - 0.041 14.2 4.4 0.066 13.6 1.9 2.8 2 1 0 2 2 2 0 STAS domain Exonuc_VII_S PF02609.16 KFM26740.1 - 0.086 12.9 0.1 17 5.6 0.1 2.8 2 0 0 2 2 2 0 Exonuclease VII small subunit Fis1_TPR_C PF14853.6 KFM26740.1 - 0.11 12.6 1.3 38 4.5 0.0 4.2 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KFM26740.1 - 0.16 12.4 2.0 4.5 7.7 0.5 2.6 2 1 0 2 2 2 0 Alkyl sulfatase dimerisation TPR_16 PF13432.6 KFM26740.1 - 0.54 11.0 0.0 0.54 11.0 0.0 6.4 5 2 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFM26740.1 - 1.2 9.3 4.5 8.5 6.7 0.0 4.4 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 KFM26740.1 - 8.2 6.7 22.9 1.1 9.5 0.6 3.9 3 1 1 4 4 3 0 Tetratricopeptide repeat NEMP PF10225.9 KFM26741.1 - 1.1e-17 64.6 2.7 1.4e-17 64.2 2.7 1.0 1 0 0 1 1 1 1 NEMP family DNase-RNase PF02577.14 KFM26742.1 - 4.1e-09 36.2 0.0 6.2e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Bifunctional nuclease UVR PF02151.19 KFM26742.1 - 0.00033 20.3 1.1 0.00033 20.3 1.1 2.6 3 0 0 3 3 3 2 UvrB/uvrC motif Malate_synthase PF01274.22 KFM26743.1 - 3.1e-209 695.6 0.0 3.5e-209 695.4 0.0 1.0 1 0 0 1 1 1 1 Malate synthase OrfB_Zn_ribbon PF07282.11 KFM26744.1 - 4.1e-05 23.4 5.8 0.00014 21.7 5.8 1.8 1 1 0 1 1 1 1 Putative transposase DNA-binding domain zf-CCCH_3 PF15663.5 KFM26744.1 - 0.056 13.7 0.7 0.084 13.1 0.7 1.3 1 0 0 1 1 1 0 Zinc-finger containing family DUF2152 PF10222.9 KFM26744.1 - 0.087 11.1 0.1 0.11 10.8 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2152) BRF1 PF07741.13 KFM26747.1 - 1.8e-24 86.0 1.0 5.7e-24 84.4 1.0 2.0 1 0 0 1 1 1 1 Brf1-like TBP-binding domain TFIIB PF00382.19 KFM26747.1 - 9.3e-24 83.3 0.1 1.6e-11 44.1 0.0 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat DUF3274 PF11678.8 KFM26747.1 - 0.018 14.3 0.4 0.039 13.2 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3274) TF_Zn_Ribbon PF08271.12 KFM26747.1 - 0.082 12.4 1.9 0.16 11.5 1.9 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding ADD_DNMT3 PF17980.1 KFM26747.1 - 0.19 11.8 1.0 0.45 10.5 1.0 1.6 1 0 0 1 1 1 0 Cysteine rich ADD domain in DNMT3 zinc_ribbon_9 PF14369.6 KFM26747.1 - 0.65 10.3 4.0 1.8 8.9 4.0 1.8 1 0 0 1 1 1 0 zinc-ribbon UQ_con PF00179.26 KFM26748.1 - 3.9e-16 59.0 0.0 4.3e-16 58.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KFM26748.1 - 0.0021 17.9 0.0 0.0025 17.7 0.0 1.1 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 KFM26748.1 - 0.055 13.8 0.0 0.055 13.8 0.0 1.2 1 0 0 1 1 1 0 RWD domain Methyltransf_11 PF08241.12 KFM26749.1 - 4.1e-18 65.8 0.0 9.1e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Sterol_MT_C PF08498.10 KFM26749.1 - 5.3e-16 58.7 0.1 1.2e-15 57.6 0.1 1.6 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_25 PF13649.6 KFM26749.1 - 1.8e-15 57.4 0.0 3.6e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM26749.1 - 4.2e-14 52.6 0.0 6.5e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KFM26749.1 - 1.7e-12 47.3 0.0 2.3e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 KFM26749.1 - 2.6e-10 40.9 0.0 4.6e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM26749.1 - 2.6e-09 37.1 0.0 3.8e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFM26749.1 - 6e-07 29.0 0.0 1.1e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.10 KFM26749.1 - 0.018 14.6 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase STT3 PF02516.14 KFM26750.1 - 2.1e-94 317.2 39.1 1.8e-93 314.1 39.1 2.0 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit CbtB PF09489.10 KFM26750.1 - 1.3 9.2 10.2 4.3 7.5 0.2 3.9 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtB) Citrate_synt PF00285.21 KFM26751.1 - 1.4e-128 429.0 0.0 1.7e-128 428.7 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Pkinase_Tyr PF07714.17 KFM26752.1 - 9.7e-36 123.4 0.0 1.2e-35 123.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM26752.1 - 3.2e-33 115.2 0.0 4.1e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 KFM26753.1 - 5.9e-32 109.2 8.5 8.9e-08 32.7 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM26753.1 - 9.6e-12 45.0 0.0 0.052 13.8 0.0 5.3 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFM26753.1 - 7.4e-05 21.9 0.0 4.8 6.0 0.0 3.7 3 1 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein HAD_2 PF13419.6 KFM26754.1 - 3.5e-06 27.2 0.0 6.4e-06 26.4 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFM26754.1 - 4.6e-05 23.8 0.0 4.8e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFM26754.1 - 0.00033 20.6 0.0 0.00053 20.0 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Flg_hook PF02120.16 KFM26754.1 - 0.16 11.9 0.3 4.7 7.2 0.0 2.3 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK tRNA_int_endo PF01974.17 KFM26756.1 - 6.2e-23 80.7 0.0 1.1e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain IBN_N PF03810.19 KFM26756.1 - 2.1e-07 30.7 0.0 7.6e-07 29.0 0.0 1.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain Importin_rep PF18773.1 KFM26756.1 - 0.059 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Importin 13 repeat YhhN PF07947.14 KFM26757.1 - 1.6e-34 119.1 18.7 1.6e-34 119.1 18.7 1.4 1 1 0 1 1 1 1 YhhN family Reticulon PF02453.17 KFM26758.1 - 2e-34 118.8 2.1 2.4e-34 118.6 2.1 1.1 1 0 0 1 1 1 1 Reticulon PRT_C PF08372.10 KFM26758.1 - 0.013 15.2 3.3 0.16 11.7 0.2 2.2 1 1 1 2 2 2 0 Plant phosphoribosyltransferase C-terminal PSI_PSAK PF01241.18 KFM26758.1 - 0.11 12.6 0.4 0.33 11.0 0.2 2.1 2 1 0 2 2 2 0 Photosystem I psaG / psaK TPR_2 PF07719.17 KFM26759.1 - 3.1e-13 48.7 9.6 6.8e-05 22.7 0.9 4.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFM26759.1 - 2.2e-11 43.0 4.0 5.7e-06 25.9 0.3 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFM26759.1 - 3.6e-08 33.0 1.9 0.12 12.1 0.1 4.0 2 1 2 4 4 4 3 TPR repeat TPR_14 PF13428.6 KFM26759.1 - 5e-08 33.1 12.3 0.0056 17.4 3.0 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFM26759.1 - 3.1e-05 23.7 1.2 0.022 14.8 0.9 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFM26759.1 - 0.00031 21.2 7.2 0.013 16.0 0.3 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFM26759.1 - 0.00034 20.8 0.4 8.1 7.1 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFM26759.1 - 0.0027 17.7 0.9 0.0071 16.4 0.3 2.0 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 KFM26759.1 - 0.0047 17.0 7.7 0.16 12.1 3.6 3.1 2 2 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFM26759.1 - 0.0073 16.4 3.1 1.1 9.6 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFM26759.1 - 0.01 16.1 8.6 0.2 12.0 4.2 3.6 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFM26759.1 - 0.056 14.1 0.8 0.056 14.1 0.8 4.4 2 2 3 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFM26759.1 - 0.14 12.1 14.2 1.3 9.0 1.8 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFM26759.1 - 0.62 10.8 5.1 8.1 7.3 0.2 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat BTAD PF03704.17 KFM26759.1 - 1 9.8 13.8 1.4 9.3 7.5 3.1 1 1 1 2 2 2 0 Bacterial transcriptional activator domain Glyco_trans_1_4 PF13692.6 KFM26760.1 - 5.4e-09 36.6 0.0 1.1e-08 35.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KFM26760.1 - 0.00029 21.1 0.0 0.00076 19.8 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KFM26760.1 - 0.0024 17.4 0.0 0.0052 16.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 HSP70 PF00012.20 KFM26761.1 - 1.1e-121 407.0 0.0 1.2e-75 254.9 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 KFM26761.1 - 8.8e-06 24.8 0.0 6.6e-05 21.9 0.0 2.1 1 1 0 2 2 2 1 MreB/Mbl protein PH PF00169.29 KFM26762.1 - 7e-12 45.8 0.0 1.5e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 PH domain WW PF00397.26 KFM26762.1 - 4.3e-08 33.1 3.3 4.3e-08 33.1 3.3 2.0 2 0 0 2 2 2 1 WW domain PH_11 PF15413.6 KFM26762.1 - 0.1 13.0 0.5 0.23 11.9 0.5 1.6 1 1 0 1 1 1 0 Pleckstrin homology domain Deltameth_res PF16020.5 KFM26762.1 - 0.29 11.0 0.1 0.29 11.0 0.1 2.0 2 0 0 2 2 2 0 Deltamethrin resistance EMP70 PF02990.16 KFM26763.1 - 4.9e-171 569.9 9.8 5.9e-171 569.7 9.8 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 Viral_NABP PF05515.11 KFM26764.1 - 0.032 14.1 0.1 0.04 13.8 0.1 1.2 1 0 0 1 1 1 0 Viral nucleic acid binding Band_7 PF01145.25 KFM26765.1 - 2.6e-30 105.7 3.2 2.7e-30 105.7 1.8 1.7 1 1 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 KFM26765.1 - 3.3e-26 91.1 0.3 6.6e-26 90.2 0.3 1.5 1 0 0 1 1 1 1 C-terminal region of band_7 Cys_rich_CPCC PF14206.6 KFM26765.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Cysteine-rich CPCC Methyltransf_11 PF08241.12 KFM26766.1 - 8.6e-18 64.8 0.1 1.3e-16 61.1 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM26766.1 - 4.2e-15 56.0 0.0 5.7e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM26766.1 - 2e-14 54.1 0.1 5.7e-07 30.1 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 KFM26766.1 - 2.1e-11 43.9 0.0 3.9e-06 26.7 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KFM26766.1 - 5.4e-11 43.1 0.0 2.4e-08 34.6 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KFM26766.1 - 4.3e-08 32.8 0.0 5.8e-07 29.1 0.0 2.4 1 1 0 2 2 2 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 KFM26766.1 - 1.5e-06 27.7 0.0 0.00018 20.9 0.0 2.3 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 KFM26766.1 - 0.00017 20.3 0.0 0.0027 16.3 0.0 2.0 1 1 1 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_8 PF05148.15 KFM26766.1 - 0.00034 20.5 0.0 0.00048 20.0 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_4 PF02390.17 KFM26766.1 - 0.00047 19.7 0.1 0.14 11.6 0.0 3.1 2 1 0 3 3 3 1 Putative methyltransferase Methyltransf_2 PF00891.18 KFM26766.1 - 0.0096 15.2 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_PK PF05891.12 KFM26766.1 - 0.02 14.4 0.1 3.7 7.0 0.0 2.1 1 1 1 2 2 2 0 AdoMet dependent proline di-methyltransferase TehB PF03848.14 KFM26766.1 - 0.036 13.5 0.0 1.6 8.1 0.0 2.2 2 0 0 2 2 2 0 Tellurite resistance protein TehB MTS PF05175.14 KFM26766.1 - 0.038 13.5 0.1 0.15 11.6 0.0 1.8 1 1 1 2 2 2 0 Methyltransferase small domain FtsJ PF01728.19 KFM26766.1 - 0.039 14.1 0.0 1.2 9.3 0.0 2.1 2 0 0 2 2 2 0 FtsJ-like methyltransferase PCMT PF01135.19 KFM26766.1 - 0.05 13.4 0.0 0.26 11.0 0.0 1.9 1 1 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.13 KFM26766.1 - 0.21 11.1 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 GFO_IDH_MocA PF01408.22 KFM26767.1 - 1.7e-14 54.6 0.0 3.3e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 KFM26767.1 - 0.0014 19.2 0.1 0.0031 18.0 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent MS_channel PF00924.18 KFM26768.1 - 6.2e-15 55.3 0.0 1.1e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel FTR1 PF03239.14 KFM26769.1 - 1.7e-38 132.5 21.2 2.5e-38 132.0 21.2 1.2 1 0 0 1 1 1 1 Iron permease FTR1 family PDR_assoc PF08370.11 KFM26769.1 - 4 7.3 9.9 0.35 10.7 0.4 3.5 4 0 0 4 4 4 0 Plant PDR ABC transporter associated SATase_N PF06426.14 KFM26770.1 - 9.3e-38 128.8 1.4 1.6e-37 128.1 1.4 1.4 1 0 0 1 1 1 1 Serine acetyltransferase, N-terminal Hexapep PF00132.24 KFM26770.1 - 5.1e-13 48.2 7.3 1.4e-07 31.0 0.1 2.4 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KFM26770.1 - 2.6e-06 27.1 11.6 5.9e-05 22.7 0.5 2.7 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase EF-hand_6 PF13405.6 KFM26771.1 - 1.7e-06 27.5 0.1 0.11 12.5 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KFM26771.1 - 2.2e-06 26.8 0.3 0.0011 18.4 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 KFM26771.1 - 3.9e-06 26.1 0.4 0.00061 19.2 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KFM26771.1 - 9.4e-06 25.4 0.5 0.00011 22.0 0.1 2.7 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.6 KFM26771.1 - 2.3e-05 24.7 0.0 5.8e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair Pkinase PF00069.25 KFM26771.1 - 0.001 18.5 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SRP54 PF00448.22 KFM26772.1 - 2.1e-66 223.3 0.0 4.2e-66 222.3 0.0 1.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 KFM26772.1 - 3.6e-10 39.9 0.0 6.9e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_16 PF13191.6 KFM26772.1 - 0.00012 22.5 2.0 0.00016 22.1 0.3 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 KFM26772.1 - 0.00015 21.6 0.5 0.00031 20.5 0.5 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KFM26772.1 - 0.0031 16.8 0.1 0.0057 15.9 0.1 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 KFM26772.1 - 0.0054 17.0 0.0 0.014 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KFM26772.1 - 0.0076 16.5 0.3 0.016 15.4 0.1 1.8 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 KFM26772.1 - 0.02 13.9 0.4 0.035 13.1 0.4 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 KFM26772.1 - 0.036 14.1 0.0 0.092 12.8 0.0 1.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.14 KFM26772.1 - 0.11 12.4 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Thymidylate_kin PF02223.17 KFM26772.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase AAA_17 PF13207.6 KFM26772.1 - 0.14 12.6 0.0 0.32 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.6 KFM26772.1 - 0.14 12.1 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF853 PF05872.12 KFM26772.1 - 0.21 10.1 0.9 0.28 9.7 0.2 1.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) AAA_23 PF13476.6 KFM26772.1 - 0.45 11.0 1.1 0.79 10.2 1.1 1.3 1 0 0 1 1 1 0 AAA domain TPR_20 PF14561.6 KFM26773.1 - 3e-18 65.9 1.1 3e-18 65.9 1.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat DEAD PF00270.29 KFM26774.1 - 1.4e-15 57.5 0.0 2.1e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 KFM26774.1 - 2.4e-15 57.0 5.8 2.4e-15 57.0 5.8 2.2 2 0 0 2 2 2 1 RecQ zinc-binding Helicase_C PF00271.31 KFM26774.1 - 5.2e-14 52.5 0.0 1e-13 51.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM26774.1 - 0.14 12.2 0.0 0.34 10.9 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit RNase_H2-Ydr279 PF09468.10 KFM26774.1 - 0.18 12.0 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain BET PF17035.5 KFM26775.1 - 1.9e-10 40.8 0.0 3.2e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Bromodomain PF00439.25 KFM26775.1 - 5.4e-06 26.4 0.0 8.7e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Bromodomain G-patch PF01585.23 KFM26776.1 - 1.3e-07 31.4 1.7 1.3e-07 31.4 1.7 2.2 2 0 0 2 2 2 1 G-patch domain SAP PF02037.27 KFM26776.1 - 4.4e-06 26.3 1.3 1.1e-05 25.1 1.3 1.7 1 0 0 1 1 1 1 SAP domain G-patch_2 PF12656.7 KFM26776.1 - 0.97 9.6 3.9 1.3 9.2 1.3 2.4 2 0 0 2 2 2 0 G-patch domain DPM3 PF08285.11 KFM26777.1 - 1.6e-16 60.3 0.5 1.8e-16 60.1 0.5 1.1 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Thioredoxin PF00085.20 KFM26778.1 - 1.7e-19 69.7 0.0 2.8e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin PUB PF09409.10 KFM26778.1 - 8.8e-16 57.6 0.0 1.3e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 PUB domain Thioredoxin_7 PF13899.6 KFM26778.1 - 1.5e-06 28.3 0.0 3.3e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KFM26778.1 - 3.3e-05 24.3 0.0 8e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 KFM26778.1 - 0.0011 18.9 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 KFM26778.1 - 0.002 18.4 0.0 0.0068 16.7 0.0 1.7 1 1 1 2 2 2 1 Thioredoxin-like TetR_C_22 PF17928.1 KFM26778.1 - 0.013 15.8 1.5 0.48 10.8 0.4 2.7 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Redoxin PF08534.10 KFM26778.1 - 0.073 12.8 0.0 0.16 11.7 0.0 1.7 1 1 0 1 1 1 0 Redoxin Thioredoxin_9 PF14595.6 KFM26778.1 - 0.15 11.8 0.1 0.37 10.6 0.0 1.6 2 0 0 2 2 2 0 Thioredoxin Ribosomal_L36 PF00444.18 KFM26779.1 - 2.5e-17 62.8 11.9 3.2e-17 62.4 11.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L36 Pyr_redox_2 PF07992.14 KFM26780.1 - 1.2e-29 103.5 0.1 2.2e-15 56.7 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFM26780.1 - 4.8e-08 33.5 0.6 0.0007 20.1 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFM26780.1 - 2.2e-05 24.5 0.8 0.027 14.5 0.0 3.0 3 0 0 3 3 3 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 KFM26780.1 - 0.057 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 KFM26780.1 - 0.13 10.9 0.1 12 4.4 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein DSPc PF00782.20 KFM26781.1 - 2.5e-21 75.9 0.0 2.8e-20 72.5 0.0 2.1 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Act-Frag_cataly PF09192.10 KFM26781.1 - 1e-05 25.1 0.0 1.5e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Actin-fragmin kinase, catalytic Y_phosphatase PF00102.27 KFM26781.1 - 0.11 12.1 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase LZ_Tnp_IS481 PF13011.6 KFM26781.1 - 1.3 9.6 4.5 5.1 7.7 0.5 3.0 2 0 0 2 2 2 0 leucine-zipper of insertion element IS481 Dymeclin PF09742.9 KFM26782.1 - 3e-78 263.8 0.0 3.9e-78 263.4 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.7 KFM26782.1 - 6.6e-05 21.3 0.0 0.57 8.2 0.0 3.7 3 1 1 4 4 4 2 High-temperature-induced dauer-formation protein FliH PF02108.16 KFM26782.1 - 0.062 13.4 0.1 0.46 10.5 0.0 2.1 2 0 0 2 2 2 0 Flagellar assembly protein FliH PseudoU_synth_1 PF01416.20 KFM26783.1 - 5.7e-27 94.3 0.0 1.6e-23 83.2 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase bZIP_1 PF00170.21 KFM26785.1 - 1.6e-15 56.9 12.4 2.6e-15 56.2 12.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFM26785.1 - 5.6e-07 29.5 12.4 1.1e-06 28.5 12.4 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFM26785.1 - 0.0092 16.5 6.4 0.021 15.4 6.4 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor MAD PF05557.13 KFM26785.1 - 0.02 13.3 2.4 0.029 12.8 2.4 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein JIP_LZII PF16471.5 KFM26785.1 - 0.092 12.9 0.1 0.27 11.4 0.1 1.7 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II Shugoshin_N PF07558.11 KFM26785.1 - 0.11 12.3 2.1 0.22 11.4 2.1 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region APG6_N PF17675.1 KFM26785.1 - 6.2 7.4 10.3 2.8 8.5 6.8 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region LSM PF01423.22 KFM26786.1 - 3.2e-20 71.6 0.1 4e-20 71.3 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KFM26786.1 - 0.0068 16.5 0.0 0.0085 16.2 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF3248 PF11609.8 KFM26787.1 - 0.1 12.5 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3248) TFIID_NTD2 PF04494.15 KFM26789.1 - 4.3e-25 88.4 0.0 6.8e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain WD40 PF00400.32 KFM26789.1 - 8.3e-13 48.6 7.3 8.5e-07 29.6 0.1 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat LisH_TPL PF17814.1 KFM26789.1 - 0.21 11.3 1.4 0.23 11.1 0.0 1.8 2 0 0 2 2 2 0 LisH-like dimerisation domain TPT PF03151.16 KFM26790.1 - 8.2e-12 45.1 9.2 1e-11 44.7 9.2 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family PUNUT PF16913.5 KFM26790.1 - 0.26 10.5 9.4 0.027 13.7 2.5 2.2 2 0 0 2 2 2 0 Purine nucleobase transmembrane transport Chorein_N PF12624.7 KFM26791.1 - 2.3e-08 34.1 0.0 4.2e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 SNF2_N PF00176.23 KFM26793.1 - 6.4e-63 212.6 0.0 1.8e-62 211.1 0.0 1.7 1 1 1 2 2 2 1 SNF2 family N-terminal domain CDP-OH_P_transf PF01066.21 KFM26793.1 - 3.6e-16 59.7 0.1 8.1e-16 58.6 0.1 1.7 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase DFRP_C PF16543.5 KFM26793.1 - 1.8e-13 50.8 2.0 1.8e-13 50.8 2.0 2.4 3 0 0 3 3 2 1 DRG Family Regulatory Proteins, Tma46 Helicase_C PF00271.31 KFM26793.1 - 1.5e-10 41.4 0.0 4.3e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Torus PF16131.5 KFM26793.1 - 4.4e-07 30.6 1.0 0.0052 17.5 0.2 3.0 2 0 0 2 2 2 2 Torus domain zf-RING_UBOX PF13445.6 KFM26793.1 - 4.6e-06 26.5 7.6 1.4e-05 25.1 7.6 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KFM26793.1 - 3.4e-05 23.9 9.7 3.4e-05 23.9 9.7 2.0 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-CCCH PF00642.24 KFM26793.1 - 0.00023 21.0 9.9 0.0016 18.3 4.3 2.6 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4 PF00097.25 KFM26793.1 - 0.00023 21.0 11.3 0.0005 19.9 11.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM26793.1 - 0.0041 17.4 11.7 0.015 15.6 11.7 2.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFM26793.1 - 0.0047 16.7 13.4 0.024 14.5 13.4 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM26793.1 - 0.005 16.8 11.4 0.012 15.6 11.4 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.6 KFM26793.1 - 0.0098 15.7 3.3 0.029 14.2 3.3 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein RSB_motif PF16294.5 KFM26793.1 - 0.012 15.8 3.8 0.012 15.8 3.8 2.1 2 0 0 2 2 2 0 RNSP1-SAP18 binding (RSB) motif zf-ribbon_3 PF13248.6 KFM26793.1 - 0.03 13.7 0.9 0.18 11.3 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-CCCH_3 PF15663.5 KFM26793.1 - 0.08 13.2 0.5 3.2 8.0 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger containing family Prok-RING_4 PF14447.6 KFM26793.1 - 0.99 9.3 9.4 2.5 8.0 9.4 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-CCCH_4 PF18044.1 KFM26793.1 - 1.9 8.4 17.7 0.39 10.6 5.6 3.2 2 1 0 2 2 2 0 CCCH-type zinc finger zf-C3HC4_3 PF13920.6 KFM26793.1 - 3 7.8 17.9 0.027 14.3 9.1 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PfkB PF00294.24 KFM26794.1 - 2.3e-58 197.9 0.0 2.7e-58 197.6 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Reticulon PF02453.17 KFM26795.1 - 2.3e-10 40.7 0.6 6.5e-10 39.2 0.4 1.8 2 0 0 2 2 2 1 Reticulon Cwf_Cwc_15 PF04889.12 KFM26796.1 - 8.2e-71 238.6 17.9 9.4e-71 238.4 17.9 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein PP28 PF10252.9 KFM26796.1 - 2.2 8.8 18.3 2 8.9 5.0 2.4 2 0 0 2 2 2 0 Casein kinase substrate phosphoprotein PP28 Cytidylate_kin PF02224.18 KFM26797.1 - 0.25 11.0 0.0 0.31 10.7 0.0 1.1 1 0 0 1 1 1 0 Cytidylate kinase BACK PF07707.15 KFM26798.1 - 3.5e-14 52.7 0.0 7.1e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch DUF4460 PF14687.6 KFM26799.1 - 2.7e-13 49.9 0.0 1e-12 48.1 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4460) DUF4461 PF14688.6 KFM26799.1 - 3e-06 27.2 0.1 0.00016 21.6 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4461) Kinesin PF00225.23 KFM26800.1 - 4.2e-101 338.2 0.0 5.8e-101 337.7 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFM26800.1 - 9.2e-23 80.8 0.0 2.9e-22 79.2 0.0 1.8 2 0 0 2 2 2 1 Microtubule binding K-box PF01486.17 KFM26800.1 - 1.8e-05 24.8 0.5 1.8e-05 24.8 0.5 3.2 2 2 2 4 4 4 1 K-box region HrpB7 PF09486.10 KFM26800.1 - 0.0018 18.7 16.8 0.0081 16.6 7.2 3.0 2 1 0 2 2 2 2 Bacterial type III secretion protein (HrpB7) DUF1192 PF06698.11 KFM26800.1 - 0.017 15.1 1.1 0.052 13.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) HAP1_N PF04849.13 KFM26800.1 - 0.019 14.2 9.2 0.33 10.1 0.7 2.4 2 0 0 2 2 2 0 HAP1 N-terminal conserved region YabA PF06156.13 KFM26800.1 - 0.2 12.3 3.8 0.24 12.0 0.1 2.8 2 1 0 2 2 2 0 Initiation control protein YabA Fungal_TACC PF12709.7 KFM26800.1 - 0.3 11.6 2.4 17 5.9 0.0 3.0 3 0 0 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins ATG16 PF08614.11 KFM26800.1 - 0.63 10.2 13.5 0.13 12.4 0.8 2.9 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) CCDC144C PF14915.6 KFM26800.1 - 0.8 8.8 9.8 0.68 9.0 0.1 3.2 2 1 1 3 3 3 0 CCDC144C protein coiled-coil region Cep57_CLD_2 PF14197.6 KFM26800.1 - 2.1 8.5 15.4 4.9 7.3 2.4 2.9 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 CENP-H PF05837.12 KFM26800.1 - 3.3 8.2 10.7 0.31 11.5 0.5 2.9 2 1 1 3 3 3 0 Centromere protein H (CENP-H) UPF0242 PF06785.11 KFM26800.1 - 4 7.5 8.6 9.2 6.3 0.2 2.6 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus ZapB PF06005.12 KFM26800.1 - 8 7.0 10.3 0.67 10.4 0.8 3.3 2 2 1 3 3 3 0 Cell division protein ZapB Fez1 PF06818.15 KFM26800.1 - 8 6.9 10.6 20 5.6 0.9 2.3 2 0 0 2 2 2 0 Fez1 FGGY_N PF00370.21 KFM26801.1 - 2.8e-48 164.6 0.0 4.3e-43 147.6 0.0 2.2 1 1 1 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KFM26801.1 - 3.1e-26 92.3 0.2 6.7e-26 91.2 0.0 1.7 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 KFM26801.1 - 0.0022 17.5 0.0 0.0049 16.4 0.0 1.5 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family DUF1118 PF06549.12 KFM26802.1 - 6.2e-34 116.8 2.5 8e-34 116.4 2.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1118) MttA_Hcf106 PF02416.16 KFM26803.1 - 1e-05 24.8 0.0 2.7e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 mttA/Hcf106 family Aha1_N PF09229.11 KFM26804.1 - 1.3e-09 38.3 0.0 1.7e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal DRMBL PF07522.14 KFM26805.1 - 4.1e-23 81.7 0.0 5.8e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 KFM26805.1 - 7.5e-05 22.3 0.9 0.00019 21.0 0.2 2.0 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Annexin_like PF18411.1 KFM26805.1 - 0.21 11.9 0.0 6.4 7.1 0.0 2.2 2 0 0 2 2 2 0 Annexin-like domain Lactamase_B PF00753.27 KFM26805.1 - 0.27 11.2 3.3 0.49 10.4 3.3 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily RNase_HII PF01351.18 KFM26806.1 - 4.4e-31 108.3 0.0 1.3e-23 83.9 0.0 2.0 2 0 0 2 2 2 2 Ribonuclease HII Pyrid_oxidase_2 PF13883.6 KFM26807.1 - 1.6e-17 64.0 0.1 6.3e-17 62.1 0.1 1.9 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 KFM26807.1 - 8.7e-07 29.1 0.0 1.7e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Forkhead PF00250.18 KFM26808.1 - 0.00021 21.5 0.0 0.00037 20.7 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain Vg_Tdu PF07545.14 KFM26809.1 - 0.22 11.3 0.1 0.51 10.2 0.1 1.6 1 0 0 1 1 1 0 Vestigial/Tondu family DnaJ PF00226.31 KFM26810.1 - 1e-23 83.2 0.8 2.9e-23 81.8 0.8 1.8 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.8 KFM26810.1 - 1.8e-10 40.8 6.4 5e-10 39.4 6.4 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFM26810.1 - 3.4e-05 24.1 4.5 7e-05 23.1 4.5 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KFM26810.1 - 0.0025 18.1 1.7 0.0025 18.1 1.7 1.9 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KFM26810.1 - 0.073 13.9 1.5 0.18 12.7 1.5 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 KFM26810.1 - 0.21 11.3 2.7 0.14 11.8 0.6 1.8 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2 PF00096.26 KFM26810.1 - 0.24 11.9 3.3 0.56 10.8 3.3 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type ABC_tran PF00005.27 KFM26810.1 - 0.31 11.6 1.5 0.6 10.6 1.5 1.6 1 1 0 1 1 1 0 ABC transporter CpXC PF14353.6 KFM26810.1 - 0.57 10.2 3.0 0.7 10.0 0.4 2.2 1 1 1 2 2 2 0 CpXC protein DBINO PF13892.6 KFM26810.1 - 2.6 8.4 17.0 0.33 11.3 12.1 1.9 2 0 0 2 2 2 0 DNA-binding domain SPOUT_MTase PF02590.17 KFM26810.1 - 8.6 6.3 7.8 24 4.9 0.3 2.3 1 1 1 2 2 2 0 Predicted SPOUT methyltransferase PRK PF00485.18 KFM26811.1 - 1.6e-73 246.7 0.0 4e-73 245.4 0.0 1.6 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.6 KFM26811.1 - 0.16 12.2 0.2 3.3 8.0 0.1 2.8 2 1 0 2 2 2 0 AAA domain 3HCDH_N PF02737.18 KFM26812.1 - 1.9e-61 207.1 0.1 2.9e-61 206.5 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KFM26812.1 - 7e-31 106.7 0.0 2.5e-30 104.9 0.0 2.0 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KFM26812.1 - 7.7e-05 22.9 0.3 0.00018 21.7 0.3 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.14 KFM26812.1 - 0.0026 17.3 0.1 0.0042 16.7 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 KFM26812.1 - 0.0091 16.6 0.1 0.019 15.5 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_2 PF07992.14 KFM26812.1 - 0.024 13.9 0.2 0.036 13.3 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase XdhC_C PF13478.6 KFM26812.1 - 0.043 14.3 0.2 0.099 13.1 0.2 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain 2-Hacid_dh_C PF02826.19 KFM26812.1 - 0.056 12.8 0.3 0.13 11.6 0.2 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 KFM26812.1 - 0.088 13.1 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_Gly3P_dh_N PF01210.23 KFM26812.1 - 0.097 12.7 0.6 0.2 11.6 0.6 1.6 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Spindle_Spc25 PF08234.12 KFM26813.1 - 6e-15 55.2 0.0 9.3e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 Pkinase_Tyr PF07714.17 KFM26814.1 - 7.7e-50 169.6 0.0 1.1e-48 165.7 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM26814.1 - 2.1e-39 135.5 0.0 8.5e-39 133.5 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 KFM26814.1 - 0.0026 17.5 1.1 0.21 11.4 0.1 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KFM26814.1 - 0.0092 16.4 0.7 0.12 12.8 0.1 2.6 1 1 0 2 2 2 1 Leucine Rich repeats (2 copies) APH PF01636.23 KFM26814.1 - 0.025 14.5 0.1 0.048 13.6 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KFM26814.1 - 0.054 12.8 0.0 0.085 12.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 KFM26814.1 - 0.084 11.8 0.0 0.33 9.9 0.0 1.7 2 0 0 2 2 2 0 Haspin like kinase domain Glycos_transf_1 PF00534.20 KFM26815.1 - 0.0063 16.1 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KFM26815.1 - 0.093 12.7 1.0 0.77 9.7 0.1 2.6 3 0 0 3 3 3 0 Glycosyltransferase Family 4 Cupin_8 PF13621.6 KFM26816.1 - 1.1e-21 77.7 0.0 2.3e-21 76.7 0.0 1.5 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 KFM26816.1 - 1.2e-15 58.0 0.1 2.1e-15 57.2 0.1 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 KFM26816.1 - 0.048 13.4 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 Cupin domain Cupin_4 PF08007.12 KFM26816.1 - 0.051 13.0 0.3 0.083 12.3 0.3 1.3 1 0 0 1 1 1 0 Cupin superfamily protein Sigma70_r2 PF04542.14 KFM26817.1 - 3.7e-15 55.4 0.4 1.5e-14 53.5 0.1 2.1 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 KFM26817.1 - 1.5e-10 40.4 2.7 2.2e-09 36.7 2.2 2.5 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r3 PF04539.16 KFM26817.1 - 5.1e-07 29.7 4.2 6.8e-06 26.1 0.1 2.8 2 0 0 2 2 2 1 Sigma-70 region 3 Prefoldin_2 PF01920.20 KFM26818.1 - 2.8e-15 56.2 0.0 3.7e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 KFM26818.1 - 0.00088 19.2 2.8 0.0097 15.8 2.8 2.0 1 1 0 1 1 1 1 Prefoldin subunit TMF_TATA_bd PF12325.8 KFM26818.1 - 0.0041 17.3 1.5 0.04 14.1 0.1 2.0 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding IES5 PF17335.2 KFM26818.1 - 0.041 14.1 0.9 0.13 12.6 0.2 1.9 2 0 0 2 2 2 0 Ino80 complex subunit 5 TPR_MLP1_2 PF07926.12 KFM26818.1 - 0.042 13.9 3.5 0.54 10.3 1.1 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF5082 PF16888.5 KFM26818.1 - 0.091 13.0 4.1 1.5 9.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) HALZ PF02183.18 KFM26818.1 - 0.13 12.5 2.4 0.26 11.6 0.2 2.3 2 1 0 2 2 2 0 Homeobox associated leucine zipper PK PF00224.21 KFM26819.1 - 8.5e-151 501.7 0.1 1.1e-150 501.4 0.1 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KFM26819.1 - 8.2e-23 80.9 0.3 2.2e-22 79.5 0.3 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain Zip PF02535.22 KFM26820.1 - 5.5e-13 48.8 13.9 2.4e-10 40.1 4.3 2.2 1 1 1 2 2 2 2 ZIP Zinc transporter Ribosomal_S2 PF00318.20 KFM26821.1 - 4.1e-25 88.3 0.2 2.1e-15 56.5 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 KFM26821.1 - 0.052 14.9 7.9 0.11 13.8 7.9 1.5 1 0 0 1 1 1 0 40S ribosomal protein SA C-terminus Alfin PF12165.8 KFM26822.1 - 2.1e-59 198.7 0.0 3.6e-59 198.0 0.0 1.4 2 0 0 2 2 2 1 Alfin LBR_tudor PF09465.10 KFM26822.1 - 0.14 11.9 0.2 0.41 10.5 0.2 1.7 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain Peptidase_S9 PF00326.21 KFM26825.1 - 1.4e-09 37.7 0.0 4.6e-06 26.3 0.0 2.5 2 0 0 2 2 2 2 Prolyl oligopeptidase family PD40 PF07676.12 KFM26825.1 - 1.3e-08 34.6 3.4 0.0037 17.1 0.0 3.5 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat DLH PF01738.18 KFM26825.1 - 0.21 11.1 0.0 0.35 10.4 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family OTU PF02338.19 KFM26826.1 - 9.4e-10 39.1 0.0 1.4e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease GATA PF00320.27 KFM26827.1 - 8.6e-06 25.3 1.9 2e-05 24.1 1.9 1.7 1 0 0 1 1 1 1 GATA zinc finger Asn_synthase PF00733.21 KFM26828.1 - 1.2e-22 81.0 1.5 2.9e-09 37.1 0.0 3.1 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 KFM26828.1 - 0.00055 19.9 0.0 0.0021 18.0 0.0 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KFM26828.1 - 0.035 14.3 0.0 0.24 11.6 0.0 2.2 2 0 0 2 2 2 0 Glutamine amidotransferase domain NAD_synthase PF02540.17 KFM26828.1 - 0.17 11.0 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 NAD synthase QueC PF06508.13 KFM26828.1 - 0.27 10.7 0.0 0.4 10.2 0.0 1.2 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC TPR_11 PF13414.6 KFM26830.1 - 4.7e-05 23.0 1.1 4.7e-05 23.0 1.1 3.4 3 1 0 3 3 3 1 TPR repeat HECT PF00632.25 KFM26832.1 - 4.1e-27 95.5 0.0 2.5e-16 60.0 0.0 2.5 1 1 1 2 2 2 2 HECT-domain (ubiquitin-transferase) IFRD PF05004.13 KFM26832.1 - 0.06 12.4 2.6 11 5.0 0.3 3.0 3 0 0 3 3 3 0 Interferon-related developmental regulator (IFRD) Arm PF00514.23 KFM26832.1 - 0.22 11.6 16.4 8.7 6.5 0.2 6.3 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KFM26832.1 - 2.4 8.7 5.4 24 5.5 0.1 4.1 3 0 0 3 3 3 0 HEAT repeat zf-HC2 PF13490.6 KFM26833.1 - 0.033 14.5 1.1 0.033 14.5 1.1 3.4 3 0 0 3 3 3 0 Putative zinc-finger DUF1732 PF08340.11 KFM26833.1 - 0.27 11.2 1.9 0.55 10.3 0.3 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF1732) DUF308 PF03729.13 KFM26833.1 - 2.2 8.7 11.1 2.5 8.5 8.6 2.1 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) PEP-utilisers_N PF05524.13 KFM26833.1 - 7.7 6.7 13.1 0.39 10.9 2.8 2.8 2 1 1 3 3 3 0 PEP-utilising enzyme, N-terminal tRNA_Me_trans PF03054.16 KFM26836.1 - 7e-65 219.1 0.0 4.5e-54 183.6 0.0 3.0 2 1 1 3 3 3 3 tRNA methyl transferase NAD_synthase PF02540.17 KFM26836.1 - 0.00046 19.4 0.0 0.00076 18.7 0.0 1.3 1 0 0 1 1 1 1 NAD synthase ThiI PF02568.14 KFM26836.1 - 0.0033 17.0 0.0 0.0048 16.5 0.0 1.2 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Asn_synthase PF00733.21 KFM26836.1 - 0.01 15.5 0.0 0.015 15.0 0.0 1.1 1 0 0 1 1 1 0 Asparagine synthase PNP_UDP_1 PF01048.20 KFM26836.1 - 0.087 12.1 0.1 0.16 11.2 0.1 1.4 1 0 0 1 1 1 0 Phosphorylase superfamily Pkr1 PF08636.10 KFM26837.1 - 2.9e-06 27.3 2.0 4.1e-06 26.8 2.0 1.2 1 0 0 1 1 1 1 ER protein Pkr1 DUF4149 PF13664.6 KFM26837.1 - 0.016 15.5 1.6 0.027 14.8 1.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4149) DUF4131 PF13567.6 KFM26837.1 - 0.038 13.6 0.5 0.039 13.6 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) TMEM219 PF14940.6 KFM26837.1 - 0.2 11.2 0.2 0.25 10.9 0.2 1.3 1 0 0 1 1 1 0 Transmembrane 219 AI-2E_transport PF01594.16 KFM26838.1 - 5.6e-33 114.5 26.2 8e-33 114.0 26.2 1.2 1 0 0 1 1 1 1 AI-2E family transporter Lipase_3 PF01764.25 KFM26839.1 - 1.7e-19 70.1 0.0 2.7e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KFM26839.1 - 0.015 15.9 0.5 0.015 15.9 0.5 2.4 1 1 1 2 2 2 0 Alpha/beta hydrolase family Thioesterase PF00975.20 KFM26839.1 - 0.065 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_1 PF00561.20 KFM26839.1 - 0.18 11.4 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Chloroa_b-bind PF00504.21 KFM26840.1 - 1.6e-36 126.2 0.2 2.3e-36 125.8 0.2 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein PPR PF01535.20 KFM26841.1 - 0.0067 16.6 0.0 1.2 9.5 0.0 3.9 3 0 0 3 3 3 1 PPR repeat Peptidase_S32 PF05579.13 KFM26841.1 - 0.091 11.9 0.2 0.17 11.1 0.2 1.3 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 TPR_4 PF07721.14 KFM26841.1 - 0.13 13.0 0.6 0.13 13.0 0.6 7.0 6 0 0 6 6 6 0 Tetratricopeptide repeat PPR_2 PF13041.6 KFM26841.1 - 0.14 12.4 0.0 20 5.5 0.0 2.8 3 0 0 3 3 3 0 PPR repeat family Peptidase_S24 PF00717.23 KFM26842.1 - 5.7e-10 39.0 0.1 8.8e-10 38.4 0.1 1.3 1 0 0 1 1 1 1 Peptidase S24-like XRN_N PF03159.18 KFM26843.1 - 6.6e-32 110.9 0.0 1.5e-31 109.6 0.0 1.6 1 1 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Kinesin PF00225.23 KFM26844.1 - 2e-101 339.3 0.0 2.4e-101 339.0 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFM26844.1 - 1.8e-19 70.1 0.0 3.1e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding TMF_DNA_bd PF12329.8 KFM26844.1 - 0.085 12.9 4.8 13 5.9 0.4 3.3 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding ZapB PF06005.12 KFM26844.1 - 0.19 12.2 7.5 12 6.4 0.1 3.4 3 0 0 3 3 3 0 Cell division protein ZapB Wtap PF17098.5 KFM26844.1 - 0.56 10.1 8.9 0.84 9.6 4.1 3.0 2 1 0 2 2 2 0 WTAP/Mum2p family Herpes_UL25 PF01499.16 KFM26844.1 - 1.5 7.2 6.0 0.65 8.5 3.6 1.5 2 0 0 2 2 2 0 Herpesvirus UL25 family MAD PF05557.13 KFM26844.1 - 1.7 6.9 7.2 0.19 10.1 2.8 1.5 2 0 0 2 2 2 0 Mitotic checkpoint protein DUF2514 PF10721.9 KFM26844.1 - 2.6 8.1 21.6 1.5 8.8 1.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2514) TPR_MLP1_2 PF07926.12 KFM26844.1 - 5.1 7.2 12.2 2.2 8.4 4.7 2.8 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein peroxidase PF00141.23 KFM26845.1 - 1.4e-48 165.6 0.0 2.1e-48 165.0 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Hydrolase_4 PF12146.8 KFM26846.1 - 2.8e-09 36.6 1.2 1.1e-07 31.4 0.9 2.1 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFM26846.1 - 2.9e-09 37.9 3.1 3.7e-09 37.5 3.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFM26846.1 - 1.2e-08 34.9 0.1 0.001 18.8 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFM26846.1 - 0.0015 18.1 1.1 0.78 9.2 0.3 2.7 2 1 1 3 3 3 2 Prolyl oligopeptidase family DUF2974 PF11187.8 KFM26846.1 - 0.028 14.0 0.3 6 6.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) DUF3530 PF12048.8 KFM26846.1 - 0.054 12.9 0.0 0.059 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Acyl_transf_2 PF02273.15 KFM26846.1 - 0.058 12.6 0.1 0.079 12.2 0.1 1.1 1 0 0 1 1 1 0 Acyl transferase Abhydrolase_2 PF02230.16 KFM26846.1 - 0.11 12.2 0.1 12 5.6 0.0 2.4 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase DUF915 PF06028.11 KFM26846.1 - 0.26 10.6 0.0 2 7.7 0.0 2.2 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) ATP-synt_C PF00137.21 KFM26849.1 - 9.4e-36 122.0 39.4 1.3e-20 73.5 16.3 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Glycophorin_A PF01102.18 KFM26849.1 - 3 8.1 5.2 0.52 10.6 1.0 1.7 2 0 0 2 2 2 0 Glycophorin A PIRT PF15099.6 KFM26849.1 - 4.6 6.8 4.7 1.6 8.3 1.2 1.8 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Pro_dh PF01619.18 KFM26850.1 - 1.4e-66 225.1 0.0 2.1e-65 221.2 0.0 2.5 2 1 0 2 2 2 1 Proline dehydrogenase EF-hand_5 PF13202.6 KFM26850.1 - 1.8e-09 36.7 1.5 6e-06 25.5 0.2 2.6 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.32 KFM26850.1 - 1.7e-07 30.2 1.3 3e-05 23.3 0.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KFM26850.1 - 3.1e-07 29.8 2.9 6.1e-05 22.6 0.7 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KFM26850.1 - 9e-07 29.3 1.2 2.5e-06 27.9 1.2 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 KFM26850.1 - 0.0029 17.4 0.0 0.0077 16.1 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFM26850.1 - 0.13 12.5 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region ATP-synt PF00231.19 KFM26852.1 - 4e-85 285.9 0.1 4.6e-85 285.7 0.1 1.0 1 0 0 1 1 1 1 ATP synthase Pex2_Pex12 PF04757.14 KFM26853.1 - 2.2e-26 92.9 0.1 3e-26 92.4 0.1 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 KFM26853.1 - 3.5e-06 26.8 0.6 5.1e-06 26.3 0.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFM26853.1 - 3.8e-05 23.4 1.5 5.8e-05 22.9 1.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM26853.1 - 0.00081 19.2 1.0 0.0012 18.6 1.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFM26853.1 - 0.013 15.5 0.7 0.03 14.4 0.7 1.6 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 KFM26853.1 - 0.027 14.8 1.6 0.057 13.7 1.6 1.5 1 1 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.6 KFM26853.1 - 0.044 13.6 2.0 1.5 8.7 0.2 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KFM26853.1 - 0.1 12.7 1.9 0.18 12.0 1.9 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DZR PF12773.7 KFM26853.1 - 0.13 12.3 0.7 0.27 11.3 0.7 1.5 1 0 0 1 1 1 0 Double zinc ribbon Paired_CXXCH_1 PF09699.10 KFM26853.1 - 0.15 11.8 0.6 0.33 10.8 0.0 1.8 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) Prok-RING_4 PF14447.6 KFM26853.1 - 0.21 11.5 1.8 0.83 9.6 2.1 1.7 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 DnaJ PF00226.31 KFM26854.1 - 7.8e-17 61.2 0.0 1.2e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Sugar_tr PF00083.24 KFM26855.1 - 2.2e-112 376.2 27.9 2.6e-112 376.0 27.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFM26855.1 - 7.1e-23 81.1 22.5 7.1e-23 81.1 22.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 KFM26855.1 - 0.011 15.4 5.3 0.011 15.4 5.3 2.9 3 1 0 3 3 3 0 Ion channel regulatory protein UNC-93 DSS1_SEM1 PF05160.13 KFM26856.1 - 2.4e-15 56.3 15.2 3.5e-15 55.8 15.2 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family Ephrin_rec_like PF07699.13 KFM26856.1 - 1.1e-07 31.4 20.5 5.3e-05 22.9 10.1 3.0 1 1 1 2 2 2 2 Putative ephrin-receptor like VSP PF03302.13 KFM26856.1 - 0.0074 15.2 11.5 0.013 14.4 11.5 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein TNFR_c6 PF00020.18 KFM26856.1 - 0.39 11.1 17.0 0.64 10.5 0.2 4.6 3 2 2 5 5 5 0 TNFR/NGFR cysteine-rich region DUF2947 PF11163.8 KFM26856.1 - 0.42 10.4 3.0 0.64 9.8 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2947) Pkinase PF00069.25 KFM26857.1 - 3.2e-45 154.6 0.0 7.5e-45 153.4 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM26857.1 - 6.7e-19 68.2 0.0 8.6e-19 67.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM26857.1 - 8.6e-05 22.0 0.2 0.23 10.7 0.0 2.1 1 1 0 2 2 2 2 Kinase-like APH PF01636.23 KFM26857.1 - 0.0028 17.6 0.0 0.16 11.8 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFM26857.1 - 0.012 15.2 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 KFM26857.1 - 0.061 12.7 0.0 0.095 12.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KFM26857.1 - 0.073 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 SHNi-TPR PF10516.9 KFM26858.1 - 1.6e-07 30.6 0.6 4.6e-07 29.2 0.6 1.8 1 0 0 1 1 1 1 SHNi-TPR TPR_2 PF07719.17 KFM26858.1 - 0.0017 18.3 6.5 0.79 10.0 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat Lzipper-MIP1 PF14389.6 KFM26858.1 - 0.031 14.6 0.0 0.061 13.6 0.0 1.5 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Med21 PF11221.8 KFM26858.1 - 0.046 14.0 1.3 0.11 12.8 1.3 1.8 1 0 0 1 1 1 0 Subunit 21 of Mediator complex SlyX PF04102.12 KFM26858.1 - 0.093 13.4 0.9 1.3 9.7 0.0 2.8 2 1 0 2 2 2 0 SlyX TPR_1 PF00515.28 KFM26858.1 - 0.33 10.9 1.4 9.9 6.2 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFM26858.1 - 0.6 10.4 11.0 0.27 11.5 2.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA PF00004.29 KFM26859.1 - 7.1e-33 113.9 0.0 7.6e-31 107.3 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFM26859.1 - 1.7e-10 40.5 0.2 4.3e-10 39.2 0.2 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KFM26859.1 - 6.4e-06 26.6 0.4 0.0042 17.5 0.2 2.6 1 1 1 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 KFM26859.1 - 0.00015 21.8 0.0 0.0005 20.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KFM26859.1 - 0.00018 21.3 0.0 0.00057 19.7 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KFM26859.1 - 0.0002 20.7 0.1 0.00046 19.5 0.0 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 KFM26859.1 - 0.00025 21.2 0.0 0.00046 20.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KFM26859.1 - 0.00039 20.7 0.2 0.0074 16.6 0.1 2.6 1 1 2 3 3 3 1 AAA domain FtsH_ext PF06480.15 KFM26859.1 - 0.00099 19.4 0.0 0.0015 18.8 0.0 1.4 1 0 0 1 1 1 1 FtsH Extracellular IstB_IS21 PF01695.17 KFM26859.1 - 0.0013 18.5 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KFM26859.1 - 0.0042 16.5 0.5 0.015 14.7 0.1 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KFM26859.1 - 0.0058 16.2 0.0 0.059 12.9 0.0 2.1 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_2 PF07724.14 KFM26859.1 - 0.016 15.3 0.0 0.032 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 KFM26859.1 - 0.018 15.6 0.0 0.048 14.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KFM26859.1 - 0.028 14.7 0.0 0.048 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KFM26859.1 - 0.032 14.2 0.0 0.056 13.5 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 KFM26859.1 - 0.068 12.9 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain CcdB PF01845.17 KFM26859.1 - 0.1 12.8 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 CcdB protein PhoH PF02562.16 KFM26859.1 - 0.2 11.1 0.2 0.34 10.3 0.2 1.3 1 0 0 1 1 1 0 PhoH-like protein FHA PF00498.26 KFM26860.1 - 1.6e-07 31.6 0.0 2.3e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KFM26860.1 - 0.081 13.3 0.0 0.17 12.2 0.0 1.6 1 1 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain PS-DH PF14765.6 KFM26861.1 - 2.3e-05 23.8 0.1 3.1e-05 23.4 0.1 1.3 1 1 0 1 1 1 1 Polyketide synthase dehydratase SMK-1 PF04802.15 KFM26862.1 - 5.1e-49 166.7 0.0 7.7e-49 166.1 0.0 1.3 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 ParE_toxin PF05016.15 KFM26862.1 - 0.068 13.8 0.1 0.25 12.0 0.1 2.0 1 0 0 1 1 1 0 ParE toxin of type II toxin-antitoxin system, parDE 60KD_IMP PF02096.20 KFM26863.1 - 3e-37 128.1 0.0 3.8e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein OSTbeta PF15048.6 KFM26863.1 - 0.036 14.2 0.0 0.058 13.5 0.0 1.3 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein PIEZO PF15917.5 KFM26863.1 - 0.045 13.2 0.1 0.061 12.8 0.1 1.1 1 0 0 1 1 1 0 Piezo 60KD_IMP PF02096.20 KFM26864.1 - 0.00038 20.4 0.1 0.00051 20.0 0.1 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein Lipase_3 PF01764.25 KFM26865.1 - 3.2e-20 72.5 0.0 5.2e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.16 KFM26865.1 - 0.0033 17.4 1.4 0.006 16.6 0.0 2.2 2 1 0 2 2 2 1 Lipase 3 N-terminal region Abhydrolase_3 PF07859.13 KFM26865.1 - 0.033 14.1 0.5 0.065 13.1 0.5 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Acatn PF13000.7 KFM26866.1 - 1.6e-121 406.5 0.0 8.9e-90 301.7 0.0 3.0 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 Ribosomal_L21p PF00829.21 KFM26867.1 - 2.4e-28 98.3 0.1 2.8e-28 98.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Ferritin_2 PF13668.6 KFM26868.1 - 6.9e-14 52.2 0.0 1.1e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain SNF2_N PF00176.23 KFM26869.1 - 6.9e-70 235.5 1.3 1.3e-69 234.6 1.3 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFM26869.1 - 2.8e-18 66.3 0.0 6.2e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM26869.1 - 1.8e-07 31.3 0.0 5.2e-07 29.8 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFM26869.1 - 2.9e-05 23.9 0.0 6.2e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DBINO PF13892.6 KFM26869.1 - 0.05 14.0 8.4 0.032 14.6 3.6 2.6 2 0 0 2 2 2 0 DNA-binding domain DUF4149 PF13664.6 KFM26873.1 - 1e-21 77.2 2.9 1e-21 77.2 2.9 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4149) DUF1772 PF08592.11 KFM26873.1 - 0.011 16.0 2.6 0.011 16.0 2.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) DUF2749 PF10907.8 KFM26873.1 - 0.27 11.5 0.0 0.27 11.5 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2749) NifU PF01106.17 KFM26875.1 - 1e-23 83.3 0.5 3.6e-20 71.9 0.1 2.8 2 1 0 2 2 2 2 NifU-like domain SPATA3 PF15662.5 KFM26875.1 - 0.013 16.1 1.9 0.022 15.4 1.9 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family DEAD PF00270.29 KFM26876.1 - 1.7e-35 122.4 0.0 3.9e-35 121.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM26876.1 - 3.9e-17 62.6 0.1 3.6e-15 56.3 0.1 2.9 2 2 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM26876.1 - 3.1e-06 27.3 0.0 5.9e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KFM26876.1 - 0.012 15.0 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit MAM33 PF02330.16 KFM26877.1 - 9.8e-35 120.4 0.1 1.2e-34 120.1 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein Proteasome PF00227.26 KFM26878.1 - 4.8e-30 104.5 0.0 5.6e-30 104.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Caudo_bapla16 PF16792.5 KFM26878.1 - 0.21 10.5 0.0 0.26 10.2 0.0 1.1 1 0 0 1 1 1 0 Phage tail base-plate attachment protein of Caudovirales ORF16 Peptidase_A22B PF04258.13 KFM26880.1 - 1.1e-77 261.4 7.0 2.8e-77 260.0 7.0 1.6 1 1 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 KFM26880.1 - 2.1e-06 27.4 7.2 5.1e-06 26.2 7.2 1.6 1 1 0 1 1 1 1 Signal-peptide peptidase, presenilin aspartyl protease Presenilin PF01080.17 KFM26880.1 - 0.0072 15.1 1.7 0.012 14.5 0.8 1.7 2 0 0 2 2 2 1 Presenilin tRNA-synt_1d PF00750.19 KFM26881.1 - 6.5e-119 396.9 0.0 8.9e-119 396.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KFM26881.1 - 3e-29 101.6 0.2 5.8e-29 100.7 0.2 1.5 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 KFM26881.1 - 3.9e-21 75.4 0.0 1.2e-20 73.9 0.0 1.8 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.19 KFM26881.1 - 0.0066 15.8 0.0 0.013 14.8 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KFM26881.1 - 0.047 12.4 0.0 0.066 12.0 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KFM26881.1 - 0.049 11.9 0.0 0.092 11.0 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) WD40 PF00400.32 KFM26882.1 - 1.8e-05 25.4 2.9 0.094 13.6 0.2 4.4 3 1 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM26882.1 - 4.8e-05 23.6 0.0 7.8 6.9 0.0 4.2 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain DUF2415 PF10313.9 KFM26882.1 - 0.011 15.6 0.1 0.044 13.7 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) SAP18 PF06487.12 KFM26883.1 - 1.8e-36 125.4 0.0 2.8e-36 124.8 0.0 1.3 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Arena_nucleocap PF00843.17 KFM26883.1 - 0.19 10.6 0.1 0.23 10.4 0.1 1.1 1 0 0 1 1 1 0 Arenavirus nucleocapsid N-terminal domain DNA_primase_lrg PF04104.14 KFM26884.1 - 7.4e-74 248.5 0.0 9.3e-74 248.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit CH_2 PF06294.11 KFM26885.1 - 4e-29 100.6 0.0 4.4e-29 100.4 0.0 1.0 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 KFM26885.1 - 1.3e-16 60.2 0.0 1.5e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 CAMSAP CH domain CH PF00307.31 KFM26885.1 - 0.044 14.0 0.0 0.047 13.9 0.0 1.2 1 0 0 1 1 1 0 Calponin homology (CH) domain AtpR PF12966.7 KFM26886.1 - 2.8e-05 24.5 1.8 2.8e-05 24.5 1.8 1.6 2 0 0 2 2 2 1 N-ATPase, AtpR subunit ATP-synt_I PF03899.15 KFM26886.1 - 0.55 10.6 5.9 1.7 9.1 5.9 1.8 1 1 0 1 1 1 0 ATP synthase I chain Arf PF00025.21 KFM26888.1 - 5.9e-33 113.8 0.3 3.4e-21 75.5 0.0 2.0 1 1 1 2 2 2 2 ADP-ribosylation factor family SRPRB PF09439.10 KFM26888.1 - 0.055 12.9 0.3 0.98 8.8 0.1 2.0 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit SKG6 PF08693.10 KFM26889.1 - 0.0089 15.4 5.3 0.018 14.5 5.3 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Pkinase PF00069.25 KFM26890.1 - 5e-56 190.0 0.0 1.6e-55 188.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM26890.1 - 1.2e-33 116.5 0.0 1.7e-33 116.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFM26890.1 - 5.1e-05 22.2 0.0 7.3e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFM26890.1 - 0.012 15.0 0.1 0.035 13.4 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 KFM26890.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3395 PF11875.8 KFM26891.1 - 5.1e-31 107.7 0.0 2.4e-30 105.5 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 KFM26891.1 - 1.9e-20 72.8 0.1 3.5e-20 71.9 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain Rhodanese PF00581.20 KFM26893.1 - 6.9e-09 36.2 0.0 8.6e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain UPF0160 PF03690.13 KFM26894.1 - 1.5e-132 442.1 0.0 1.7e-132 441.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) ATP-synt_ab PF00006.25 KFM26897.1 - 9.3e-105 349.0 0.0 1.3e-104 348.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 KFM26897.1 - 5.7e-46 155.3 0.0 9.8e-46 154.6 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 KFM26897.1 - 6e-15 55.5 2.0 5e-14 52.6 1.4 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain Myosin_N PF02736.19 KFM26897.1 - 0.12 12.2 0.6 0.55 10.1 0.2 2.2 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain Histone PF00125.24 KFM26898.1 - 4.7e-19 69.0 0.7 5.9e-19 68.7 0.7 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFM26898.1 - 0.00082 19.6 0.0 0.0024 18.1 0.0 1.8 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YscO-like PF16789.5 KFM26898.1 - 0.011 15.8 0.2 0.013 15.5 0.2 1.1 1 0 0 1 1 1 0 YscO-like protein TFIID_20kDa PF03847.13 KFM26898.1 - 0.046 14.2 0.0 0.084 13.4 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A RP-C PF03428.13 KFM26898.1 - 0.062 13.0 0.1 0.24 11.1 0.0 1.8 1 1 1 2 2 2 0 Replication protein C N-terminal domain DIM1 PF02966.16 KFM26899.1 - 3.3e-44 149.9 0.1 4.1e-44 149.6 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 DUF382 PF04037.13 KFM26900.1 - 3.1e-58 195.4 0.2 3.1e-58 195.4 0.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.16 KFM26900.1 - 2.5e-19 68.8 5.0 5e-19 67.9 5.0 1.5 1 0 0 1 1 1 1 PSP HEAT PF02985.22 KFM26901.1 - 2.8e-09 36.4 21.7 0.57 10.6 0.2 9.9 9 0 0 9 9 9 5 HEAT repeat HEAT_EZ PF13513.6 KFM26901.1 - 1.1e-08 35.4 0.9 1.1e-08 35.4 0.9 10.9 8 2 1 10 10 10 3 HEAT-like repeat HEAT_2 PF13646.6 KFM26901.1 - 5.8e-07 29.8 20.3 0.012 15.9 0.5 7.4 5 2 3 8 8 8 4 HEAT repeats IBN_N PF03810.19 KFM26901.1 - 0.0011 18.9 0.0 0.004 17.0 0.0 2.0 1 1 1 2 2 2 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 KFM26901.1 - 0.18 12.4 0.0 10 6.8 0.0 3.1 3 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region DUF3730 PF12530.8 KFM26901.1 - 0.35 10.4 1.5 1.3 8.5 0.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3730) Mpv17_PMP22 PF04117.12 KFM26902.1 - 6.3e-16 58.4 1.6 1.8e-15 56.9 0.1 2.1 2 0 0 2 2 2 1 Mpv17 / PMP22 family TerC PF03741.16 KFM26903.1 - 3.2e-43 147.5 11.3 5e-43 146.9 11.3 1.3 1 0 0 1 1 1 1 Integral membrane protein TerC family MIF4G PF02854.19 KFM26904.1 - 9.7e-56 188.7 0.0 1.3e-32 113.2 0.0 2.2 1 1 1 2 2 2 2 MIF4G domain FANCI_S2 PF14676.6 KFM26904.1 - 0.00012 22.5 2.4 0.57 10.5 0.2 3.1 3 0 0 3 3 3 2 FANCI solenoid 2 DUF4333 PF14230.6 KFM26904.1 - 0.0012 19.0 0.1 3.2 8.0 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4333) U3snoRNP10 PF12397.8 KFM26904.1 - 0.0033 17.7 0.0 5.6 7.3 0.0 2.9 3 1 0 3 3 3 2 U3 small nucleolar RNA-associated protein 10 SMC_Nse1 PF07574.13 KFM26904.1 - 0.0037 17.2 1.9 5 7.0 0.0 3.3 3 1 0 3 3 3 2 Nse1 non-SMC component of SMC5-6 complex CNOT1_CAF1_bind PF16415.5 KFM26904.1 - 0.032 13.6 0.0 0.063 12.7 0.0 1.4 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 CAF1-binding domain hDGE_amylase PF14701.6 KFM26904.1 - 0.048 12.8 4.0 3.3 6.7 0.0 2.9 1 1 3 4 4 4 0 Glycogen debranching enzyme, glucanotransferase domain PRCC PF10253.9 KFM26904.1 - 0.086 13.6 11.2 0.17 12.6 11.2 1.4 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting PABP PF00658.18 KFM26904.1 - 0.09 13.0 0.0 30 4.9 0.0 2.8 2 0 0 2 2 2 0 Poly-adenylate binding protein, unique domain Transposase_22 PF02994.14 KFM26904.1 - 0.15 12.3 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 L1 transposable element RBD-like domain DUF445 PF04286.12 KFM26904.1 - 0.32 10.8 8.0 0.12 12.1 4.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF445) CRR7 PF12095.8 KFM26904.1 - 0.49 10.9 5.3 18 5.8 0.1 3.4 4 0 0 4 4 3 0 Protein CHLORORESPIRATORY REDUCTION 7 DUF4307 PF14155.6 KFM26906.1 - 0.054 13.3 0.1 0.068 13.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) Na_H_Exchanger PF00999.21 KFM26907.1 - 1e-19 70.6 27.4 1e-19 70.6 27.4 1.7 2 0 0 2 2 2 1 Sodium/hydrogen exchanger family DUF2157 PF09925.9 KFM26907.1 - 0.016 15.0 1.3 0.016 15.0 1.3 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2157) XPG_I PF00867.18 KFM26908.1 - 8.3e-29 99.8 0.1 1.9e-28 98.6 0.1 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KFM26908.1 - 3.9e-21 75.4 0.1 9.7e-21 74.2 0.0 1.7 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.20 KFM26908.1 - 0.0048 17.5 0.0 0.011 16.3 0.0 1.6 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold DUF863 PF05904.11 KFM26908.1 - 0.054 11.9 0.0 0.077 11.4 0.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF863) Polysacc_deac_1 PF01522.21 KFM26909.1 - 0.015 15.2 0.1 0.046 13.6 0.1 1.9 1 1 0 1 1 1 0 Polysaccharide deacetylase Ribosomal_S17_N PF16205.5 KFM26910.1 - 1.7e-29 101.9 0.8 3.2e-29 101.1 0.8 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 KFM26910.1 - 1.9e-24 85.6 0.2 2.7e-24 85.1 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 IQ PF00612.27 KFM26911.1 - 3.1e-20 70.0 133.5 0.004 16.8 1.2 17.3 17 0 0 17 17 17 13 IQ calmodulin-binding motif CH PF00307.31 KFM26911.1 - 0.0047 17.1 0.0 9 6.5 0.0 3.6 3 1 0 3 3 3 1 Calponin homology (CH) domain PXA PF02194.15 KFM26911.1 - 2.7 7.9 4.5 0.64 10.0 0.3 2.1 2 0 0 2 2 2 0 PXA domain TRAM_LAG1_CLN8 PF03798.16 KFM26912.1 - 4e-25 88.7 12.6 4.9e-25 88.4 12.6 1.0 1 0 0 1 1 1 1 TLC domain DUF3783 PF12646.7 KFM26914.1 - 0.00014 21.8 0.0 0.00026 20.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3783) 2OG-FeII_Oxy_2 PF13532.6 KFM26915.1 - 3.2e-30 105.8 0.0 3.4e-30 105.7 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KFM26915.1 - 0.03 14.8 0.0 0.076 13.5 0.0 1.7 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily RRM_1 PF00076.22 KFM26916.1 - 5.3e-16 58.2 0.0 6.7e-16 57.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFM26916.1 - 2e-07 30.7 0.0 2.6e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFM26916.1 - 0.00011 22.2 0.0 0.00015 21.7 0.0 1.2 1 0 0 1 1 1 1 RNA binding motif AMPK1_CBM PF16561.5 KFM26917.1 - 1.1e-28 99.2 0.0 1.8e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBS PF00571.28 KFM26917.1 - 1.6e-18 66.9 1.0 6.1e-07 29.8 0.3 4.5 4 0 0 4 4 4 4 CBS domain CBM_48 PF02922.18 KFM26917.1 - 0.00014 22.1 0.0 0.00031 21.0 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Pkinase PF00069.25 KFM26918.1 - 7.8e-11 41.8 0.0 1.2e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM26918.1 - 4.9e-05 22.7 0.0 0.00017 21.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM26919.1 - 5.6e-55 186.6 0.0 7.8e-55 186.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM26919.1 - 6.6e-22 78.0 0.0 9.5e-22 77.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_8 PF13833.6 KFM26919.1 - 3.7e-09 36.3 0.0 2.7e-06 27.1 0.0 3.2 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 KFM26919.1 - 1e-06 28.1 0.0 0.0037 17.1 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KFM26919.1 - 1.4e-06 28.7 0.0 0.041 14.3 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KFM26919.1 - 1.6e-06 27.2 0.0 0.02 14.4 0.0 2.8 2 0 0 2 2 2 2 EF hand Pkinase_fungal PF17667.1 KFM26919.1 - 0.00028 19.8 0.0 0.00065 18.6 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase EF-hand_5 PF13202.6 KFM26919.1 - 0.002 17.5 0.5 1 8.9 0.5 2.6 2 0 0 2 2 2 2 EF hand APH PF01636.23 KFM26919.1 - 0.014 15.4 0.9 0.22 11.4 0.0 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family Trehalose_PPase PF02358.16 KFM26920.1 - 1.2e-57 194.7 0.0 1.5e-57 194.4 0.0 1.1 1 0 0 1 1 1 1 Trehalose-phosphatase HAD PF12710.7 KFM26920.1 - 0.052 13.9 0.0 0.23 11.8 0.0 2.0 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KFM26920.1 - 0.069 12.9 0.0 2.5 7.8 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase BNR_2 PF13088.6 KFM26921.1 - 0.0024 17.3 1.3 0.09 12.1 0.1 2.8 3 1 0 3 3 3 2 BNR repeat-like domain Prominin PF05478.11 KFM26921.1 - 3.2 5.6 4.2 6.7 4.5 0.1 2.0 2 0 0 2 2 2 0 Prominin DEAD PF00270.29 KFM26922.1 - 2.7e-48 164.0 0.0 5.8e-48 163.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM26922.1 - 7e-33 113.3 0.0 5.8e-31 107.1 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KFM26922.1 - 2.5e-05 23.6 0.0 4.1e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KFM26922.1 - 0.0021 18.1 0.0 0.0068 16.4 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 KFM26922.1 - 0.032 13.0 0.0 0.095 11.5 0.0 1.7 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 CMS1 PF14617.6 KFM26922.1 - 0.055 12.8 0.0 0.055 12.8 0.0 1.6 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit NAD_kinase PF01513.21 KFM26923.1 - 1.3e-50 172.2 0.0 6.7e-50 169.9 0.0 1.8 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KFM26923.1 - 0.011 15.4 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain TPALS PF18178.1 KFM26923.1 - 0.14 11.5 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 TIR- and PNP-associating SLOG family E1_dh PF00676.20 KFM26924.1 - 1.9e-76 256.9 0.0 2.4e-76 256.6 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KFM26924.1 - 1.2e-06 28.4 0.1 2.2e-06 27.5 0.1 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 KFM26924.1 - 0.01 15.1 0.1 0.021 14.1 0.0 1.5 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase FeS_assembly_P PF01883.19 KFM26925.1 - 2.2e-12 47.0 0.3 5.6e-12 45.6 0.0 1.8 2 1 0 2 2 2 1 Iron-sulfur cluster assembly protein Big_8 PF17961.1 KFM26925.1 - 0.19 11.9 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial Ig domain Peptidase_S9 PF00326.21 KFM26926.1 - 0.0018 17.8 0.0 0.2 11.1 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KFM26926.1 - 0.0029 17.3 0.0 0.0044 16.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFM26926.1 - 0.0072 17.0 15.7 0.03 14.9 8.4 2.6 2 2 0 2 2 2 2 Alpha/beta hydrolase family MRP-L47 PF06984.13 KFM26928.1 - 1.5e-23 82.7 1.2 1.7e-23 82.5 1.2 1.1 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.23 KFM26928.1 - 0.00018 21.4 0.9 0.00025 21.0 0.9 1.2 1 0 0 1 1 1 1 Ribosomal L29 protein Chorismate_bind PF00425.18 KFM26929.1 - 3.9e-76 256.0 0.0 3.4e-75 252.9 0.0 2.4 2 1 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 KFM26929.1 - 3.6e-28 98.6 0.0 5.8e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Ebp2 PF05890.12 KFM26930.1 - 2.2e-64 217.6 18.7 2.5e-64 217.4 18.7 1.0 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 IMD PF08397.11 KFM26930.1 - 0.0035 16.8 7.9 0.0048 16.3 7.9 1.3 1 0 0 1 1 1 1 IRSp53/MIM homology domain PDZ_3 PF17815.1 KFM26933.1 - 1.2e-43 148.4 0.0 1.7e-43 147.9 0.0 1.2 1 0 0 1 1 1 1 PDZ domain Trypsin_2 PF13365.6 KFM26933.1 - 2.1e-22 80.7 2.2 6.9e-22 79.0 2.7 1.6 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.26 KFM26933.1 - 3.2e-16 59.8 0.0 5.4e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 KFM26933.1 - 4.8e-07 30.0 0.1 3.8e-06 27.1 0.0 2.4 3 0 0 3 3 3 1 PDZ domain PDZ_6 PF17820.1 KFM26933.1 - 0.00027 20.7 0.1 0.47 10.3 0.0 2.9 2 0 0 2 2 2 2 PDZ domain Peptidase_S46 PF10459.9 KFM26933.1 - 0.037 12.7 1.4 0.067 11.8 0.1 1.9 2 0 0 2 2 2 0 Peptidase S46 Peptidase_S39 PF02122.15 KFM26933.1 - 0.088 12.3 0.0 1 8.8 0.0 2.1 2 0 0 2 2 2 0 Peptidase S39 TPR_16 PF13432.6 KFM26934.1 - 4.6e-05 24.0 6.0 0.003 18.2 0.9 4.5 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFM26934.1 - 0.00079 19.9 10.3 0.01 16.3 2.4 5.2 5 1 2 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 KFM26934.1 - 0.0034 17.5 15.5 0.0064 16.6 1.7 4.0 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFM26934.1 - 0.019 15.0 10.2 0.25 11.6 0.4 4.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFM26934.1 - 0.029 14.6 1.0 4.6 7.7 0.3 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFM26934.1 - 0.63 10.0 4.4 6.7 6.7 0.4 3.8 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFM26934.1 - 0.98 10.4 21.9 0.6 11.1 0.9 5.7 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFM26934.1 - 2.2 8.1 7.3 4.2 7.1 0.1 3.8 4 1 0 4 4 4 0 TPR repeat vATP-synt_E PF01991.18 KFM26935.1 - 1.8e-62 210.3 6.8 2e-62 210.1 6.8 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit TcdA_TcdB_pore PF12920.7 KFM26935.1 - 0.021 13.1 0.8 0.025 12.9 0.8 1.1 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain tRNA-synt_2 PF00152.20 KFM26935.1 - 1.4 8.0 4.9 2.1 7.3 4.9 1.3 1 1 0 1 1 1 0 tRNA synthetases class II (D, K and N) Phlebovirus_NSM PF07246.11 KFM26935.1 - 1.5 8.2 6.4 2.1 7.7 6.4 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF45 PF01863.17 KFM26935.1 - 2.2 8.3 8.0 1.3 9.1 2.7 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF45 DUF848 PF05852.11 KFM26935.1 - 3.2 7.8 11.7 6.8 6.8 4.0 2.3 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Myb_DNA-binding PF00249.31 KFM26936.1 - 6.6e-06 26.2 0.0 1.3e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain SlyX PF04102.12 KFM26936.1 - 0.017 15.7 10.8 0.67 10.6 0.0 3.7 3 0 0 3 3 3 0 SlyX Cluap1 PF10234.9 KFM26936.1 - 0.018 14.4 0.2 6.7 6.0 0.0 2.3 2 0 0 2 2 2 0 Clusterin-associated protein-1 IFT20 PF14931.6 KFM26936.1 - 0.099 12.8 1.2 20 5.4 0.1 2.6 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 DUF3837 PF12939.7 KFM26936.1 - 0.16 12.4 0.0 43 4.6 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3837) DivIC PF04977.15 KFM26936.1 - 0.35 10.7 14.3 0.78 9.6 0.2 3.3 3 0 0 3 3 3 0 Septum formation initiator Spc42p PF11544.8 KFM26936.1 - 0.78 9.8 6.1 9.4 6.3 0.0 2.7 3 0 0 3 3 3 0 Spindle pole body component Spc42p T2SSM PF04612.12 KFM26936.1 - 1.4 8.9 0.0 1.4 8.9 0.0 4.4 4 0 0 4 4 4 0 Type II secretion system (T2SS), protein M bZIP_1 PF00170.21 KFM26936.1 - 2 8.5 4.2 36 4.5 0.3 2.5 2 0 0 2 2 2 0 bZIP transcription factor TPR_14 PF13428.6 KFM26937.1 - 2.7e-22 77.5 67.4 8e-06 26.3 4.6 11.7 5 3 6 11 11 11 9 Tetratricopeptide repeat TPR_19 PF14559.6 KFM26937.1 - 3e-14 53.2 32.4 7.8e-07 29.5 5.9 7.3 5 3 1 6 6 6 3 Tetratricopeptide repeat PRP1_N PF06424.12 KFM26937.1 - 3.1e-14 53.6 0.4 2.1e-12 47.7 0.4 2.3 1 1 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_2 PF07719.17 KFM26937.1 - 1e-05 25.3 25.0 0.79 10.0 0.0 8.1 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFM26937.1 - 1.4e-05 25.0 0.4 1.9 8.9 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFM26937.1 - 8.9e-05 22.6 4.9 1.2e+02 3.4 0.0 8.6 9 3 1 10 10 9 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFM26937.1 - 0.00015 22.4 67.0 0.011 16.3 3.2 8.2 5 3 6 11 11 10 6 Tetratricopeptide repeat Suf PF05843.14 KFM26937.1 - 0.0011 19.0 0.0 0.31 11.0 0.0 2.9 3 0 0 3 3 3 1 Suppressor of forked protein (Suf) NARP1 PF12569.8 KFM26937.1 - 0.0039 16.2 0.9 1 8.2 0.0 3.1 2 1 0 3 3 3 1 NMDA receptor-regulated protein 1 DUF3808 PF10300.9 KFM26937.1 - 0.35 9.6 0.5 2.8 6.6 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3808) TPR_1 PF00515.28 KFM26937.1 - 0.89 9.5 2.8 9.9 6.2 0.0 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat HAT PF02184.16 KFM26937.1 - 2.2 8.3 5.2 7.6 6.6 0.1 3.9 4 0 0 4 4 4 0 HAT (Half-A-TPR) repeat MFS_1 PF07690.16 KFM26938.1 - 1.8e-25 89.6 23.3 2.6e-21 76.0 6.9 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily Nop52 PF05997.12 KFM26939.1 - 2.7e-55 187.5 0.1 3.4e-55 187.2 0.1 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 DUF908 PF06012.12 KFM26939.1 - 0.24 10.7 1.6 0.84 9.0 0.0 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) zf-C3HC4_3 PF13920.6 KFM26940.1 - 9.2e-10 38.2 5.4 1.4e-09 37.6 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM26940.1 - 2e-09 37.6 11.0 3.2e-09 37.0 11.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KFM26940.1 - 3.3e-08 33.3 9.7 5.1e-08 32.6 9.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFM26940.1 - 7.7e-08 32.2 9.3 1.3e-07 31.5 9.3 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KFM26940.1 - 1.9e-07 31.2 5.9 3.4e-07 30.4 5.9 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KFM26940.1 - 4e-07 29.9 8.7 2.9e-06 27.1 8.7 2.1 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFM26940.1 - 1.4e-06 28.0 10.8 2.5e-06 27.2 10.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFM26940.1 - 1.2e-05 25.1 10.3 8.1e-05 22.4 10.9 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KFM26940.1 - 0.00018 21.6 12.4 0.00083 19.5 11.8 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 KFM26940.1 - 0.00051 20.0 2.6 0.0009 19.3 2.6 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FdhE PF04216.12 KFM26940.1 - 0.008 16.1 5.3 0.011 15.6 5.3 1.3 1 0 0 1 1 1 1 Protein involved in formate dehydrogenase formation Rad50_zn_hook PF04423.14 KFM26940.1 - 0.016 15.1 0.5 0.37 10.7 0.0 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_6 PF14835.6 KFM26940.1 - 0.058 13.3 6.7 0.66 9.9 6.0 2.2 1 1 1 2 2 2 0 zf-RING of BARD1-type protein DUF2165 PF09933.9 KFM26940.1 - 0.1 12.6 6.7 0.15 12.0 6.4 1.4 1 1 0 1 1 1 0 Predicted small integral membrane protein (DUF2165) Zn_ribbon_17 PF17120.5 KFM26940.1 - 0.14 11.8 6.6 0.29 10.8 6.6 1.6 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type GAGA PF09237.11 KFM26940.1 - 0.26 11.1 1.2 19 5.2 0.1 2.3 2 0 0 2 2 2 0 GAGA factor zinc-ribbons_6 PF07191.12 KFM26940.1 - 0.28 11.2 6.5 0.48 10.4 6.5 1.4 1 0 0 1 1 1 0 zinc-ribbons zf-RING_10 PF16685.5 KFM26940.1 - 0.41 10.8 7.2 0.33 11.1 5.4 1.8 2 0 0 2 2 2 0 zinc RING finger of MSL2 DZR PF12773.7 KFM26940.1 - 0.68 10.0 7.2 1.2 9.2 6.6 1.6 1 1 1 2 2 2 0 Double zinc ribbon zf-RING_4 PF14570.6 KFM26940.1 - 0.82 9.5 9.7 3.7 7.4 4.7 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Ribosomal_S17 PF00366.20 KFM26941.1 - 6e-24 83.9 1.7 7.7e-24 83.6 1.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 DUF5027 PF16430.5 KFM26941.1 - 0.043 13.6 0.0 0.049 13.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5027) EamA PF00892.20 KFM26942.1 - 1.7e-08 34.8 20.9 4e-08 33.5 0.8 2.8 3 1 0 3 3 3 2 EamA-like transporter family SLC35F PF06027.12 KFM26942.1 - 1.3e-05 24.9 1.3 3.1e-05 23.6 0.0 2.0 3 0 0 3 3 3 1 Solute carrier family 35 CRT-like PF08627.10 KFM26942.1 - 0.00011 21.3 0.1 0.003 16.6 0.0 2.1 1 1 1 2 2 2 1 CRT-like, chloroquine-resistance transporter-like Bax1-I PF01027.20 KFM26942.1 - 0.0018 18.2 12.0 0.022 14.6 2.0 2.5 1 1 1 2 2 2 2 Inhibitor of apoptosis-promoting Bax1 TMEM234 PF10639.9 KFM26942.1 - 0.0093 16.0 0.0 0.046 13.7 0.0 2.0 2 0 0 2 2 2 1 Putative transmembrane family 234 Nuc_sug_transp PF04142.15 KFM26942.1 - 0.042 13.0 0.3 0.086 12.0 0.3 1.5 1 0 0 1 1 1 0 Nucleotide-sugar transporter zf-RING_2 PF13639.6 KFM26943.1 - 3e-07 30.7 1.9 3e-07 30.7 1.9 2.0 3 0 0 3 3 2 1 Ring finger domain PHD PF00628.29 KFM26943.1 - 0.0003 20.6 2.4 0.00051 19.9 2.4 1.4 1 0 0 1 1 1 1 PHD-finger zf-RING_UBOX PF13445.6 KFM26943.1 - 0.0016 18.4 0.0 0.0042 17.1 0.0 1.8 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_1 PF14446.6 KFM26943.1 - 0.0021 17.9 2.4 0.0071 16.2 0.8 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 C1_1 PF00130.22 KFM26943.1 - 0.0078 16.1 3.9 0.0093 15.8 1.0 2.2 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-UDP PF14569.6 KFM26943.1 - 0.019 15.1 0.9 0.036 14.2 0.9 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_4 PF14570.6 KFM26943.1 - 0.025 14.4 2.3 0.048 13.5 2.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 KFM26943.1 - 0.026 14.6 2.8 0.064 13.4 2.8 1.7 1 1 0 1 1 1 0 RING-variant domain PHD_4 PF16866.5 KFM26943.1 - 0.028 14.5 3.7 0.11 12.6 3.8 2.0 1 1 0 1 1 1 0 PHD-finger zf-ANAPC11 PF12861.7 KFM26943.1 - 0.028 14.5 4.3 0.16 12.1 4.3 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger SWIM PF04434.17 KFM26943.1 - 0.052 13.2 0.0 0.13 11.9 0.0 1.8 1 0 0 1 1 1 0 SWIM zinc finger zf-rbx1 PF12678.7 KFM26943.1 - 0.064 13.5 7.3 0.3 11.4 7.3 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain FANCL_C PF11793.8 KFM26943.1 - 0.082 13.1 5.7 0.31 11.2 5.7 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 KFM26943.1 - 0.17 12.1 5.1 0.35 11.1 0.5 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF1360 PF07098.11 KFM26943.1 - 0.18 11.8 1.3 0.44 10.5 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1360) zf-C3HC4 PF00097.25 KFM26943.1 - 0.57 10.1 5.2 0.22 11.4 1.6 2.2 2 1 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFM26943.1 - 0.61 10.0 6.4 6.1 6.8 6.4 2.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zf_RING PF16744.5 KFM26943.1 - 0.78 9.9 3.7 2.7 8.1 3.7 1.9 1 1 0 1 1 1 0 KIAA1045 RING finger zf-TFIIB PF13453.6 KFM26943.1 - 2.1 7.8 7.6 0.68 9.3 3.7 2.1 2 0 0 2 2 2 0 Transcription factor zinc-finger Zn_ribbon_17 PF17120.5 KFM26943.1 - 2.3 7.9 7.5 1.6 8.4 5.0 2.1 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type PUF PF00806.19 KFM26944.1 - 4.2e-06 26.2 0.0 0.99 9.2 0.0 4.8 5 0 0 5 5 5 2 Pumilio-family RNA binding repeat DAGK_cat PF00781.24 KFM26944.1 - 0.068 12.8 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain ORC5_C PF14630.6 KFM26945.1 - 2.2e-43 148.8 0.0 2.7e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 KFM26945.1 - 2.4e-12 47.6 2.0 3.9e-12 46.9 0.2 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KFM26945.1 - 6.8e-05 23.2 0.0 0.00012 22.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KFM26945.1 - 0.00095 19.6 0.0 0.0017 18.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KFM26945.1 - 0.13 11.7 0.1 0.23 10.8 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KFM26945.1 - 0.15 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_11 PF13086.6 KFM26945.1 - 0.19 11.5 0.0 0.29 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 KFM26945.1 - 0.28 10.3 0.0 0.4 9.8 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain ABC_membrane PF00664.23 KFM26946.1 - 1.7e-58 198.4 27.8 3.4e-31 108.9 11.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFM26946.1 - 1.8e-53 180.7 0.0 2.7e-29 102.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KFM26946.1 - 1.1e-07 31.5 2.6 0.89 8.9 0.3 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KFM26946.1 - 2.4e-06 27.6 0.4 0.095 12.8 0.1 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFM26946.1 - 1.7e-05 24.8 0.5 0.0039 17.1 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KFM26946.1 - 3.7e-05 24.2 0.4 0.093 13.1 0.1 3.2 2 1 1 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 KFM26946.1 - 0.00017 21.3 0.2 0.31 10.8 0.0 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_7 PF12775.7 KFM26946.1 - 0.00058 19.4 0.1 0.19 11.2 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_22 PF13401.6 KFM26946.1 - 0.00092 19.5 0.8 4.1 7.7 0.0 3.7 4 0 0 4 4 4 1 AAA domain DUF815 PF05673.13 KFM26946.1 - 0.0015 17.7 0.1 0.17 11.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) DUF87 PF01935.17 KFM26946.1 - 0.015 15.4 0.3 0.36 10.9 0.1 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain NACHT PF05729.12 KFM26946.1 - 0.05 13.5 0.6 4 7.3 0.1 2.9 3 0 0 3 3 3 0 NACHT domain AAA PF00004.29 KFM26946.1 - 0.11 12.9 0.2 7.7 6.9 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.23 KFM26946.1 - 0.12 12.5 2.5 4.4 7.3 0.0 2.5 2 0 0 2 2 2 0 Dynamin family Roc PF08477.13 KFM26946.1 - 0.16 12.2 5.5 4.5 7.5 0.1 3.4 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 KFM26946.1 - 0.18 10.9 0.5 15 4.7 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain Mg_trans_NIPA PF05653.14 KFM26947.1 - 2.2e-90 302.7 11.0 2.8e-90 302.4 11.0 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KFM26947.1 - 9.3e-06 25.9 6.4 9.3e-06 25.9 6.4 2.8 2 1 1 3 3 3 1 EamA-like transporter family OrfB_Zn_ribbon PF07282.11 KFM26947.1 - 0.0049 16.7 6.7 0.018 15.0 6.7 1.9 1 1 0 1 1 1 1 Putative transposase DNA-binding domain F-box-like PF12937.7 KFM26948.1 - 0.016 15.1 0.0 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 KFM26948.1 - 0.095 12.6 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 F-box domain SNARE PF05739.19 KFM26948.1 - 0.3 11.1 0.1 0.3 11.1 0.1 1.5 2 0 0 2 2 2 0 SNARE domain DUF4381 PF14316.6 KFM26949.1 - 0.83 9.9 5.9 0.48 10.7 3.4 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4381) RtcB PF01139.17 KFM26950.1 - 4.5e-151 503.7 0.1 5.2e-151 503.5 0.1 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB NPL PF17800.1 KFM26952.1 - 1.7e-09 38.2 0.1 2.6e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 Nucleoplasmin-like domain Clat_adaptor_s PF01217.20 KFM26953.1 - 4.7e-43 146.5 2.4 5.3e-43 146.4 2.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DNA_pol_viral_C PF00336.18 KFM26953.1 - 0.038 13.4 0.0 0.06 12.7 0.0 1.3 1 1 0 1 1 1 0 DNA polymerase (viral) C-terminal domain 2_5_RNA_ligase2 PF13563.6 KFM26954.1 - 2.3e-10 40.6 0.1 2.8e-10 40.3 0.1 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily HD_3 PF13023.6 KFM26955.1 - 7e-41 139.9 0.0 8.1e-41 139.7 0.0 1.0 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 KFM26955.1 - 1.4e-10 41.2 0.0 2.1e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 KFM26955.1 - 0.0043 17.3 0.0 0.0073 16.5 0.0 1.4 1 0 0 1 1 1 1 HD domain Translin PF01997.16 KFM26957.1 - 1.4e-30 106.9 1.4 1.4e-29 103.6 1.4 2.0 1 1 0 1 1 1 1 Translin family T3SS_needle_E PF08988.10 KFM26957.1 - 0.052 13.7 7.1 0.066 13.4 4.6 2.2 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle HemY_N PF07219.13 KFM26957.1 - 0.31 11.3 2.1 0.64 10.2 1.5 1.8 2 0 0 2 2 2 0 HemY protein N-terminus Ribosomal_L13 PF00572.18 KFM26958.1 - 4.5e-50 169.1 0.0 5.7e-50 168.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 DUF3659 PF12396.8 KFM26958.1 - 0.1 12.6 0.1 0.24 11.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) eIF-6 PF01912.18 KFM26959.1 - 7.6e-77 257.2 0.9 1.1e-76 256.6 0.5 1.4 2 0 0 2 2 2 1 eIF-6 family SNARE PF05739.19 KFM26960.1 - 8.7e-13 48.1 0.4 6.2e-12 45.3 0.1 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 KFM26960.1 - 2e-07 30.9 0.2 0.004 16.9 0.0 2.3 2 0 0 2 2 2 2 Syntaxin Syntaxin-5_N PF11416.8 KFM26960.1 - 2.1e-05 23.6 0.2 0.00016 20.8 0.1 2.4 2 0 0 2 2 2 1 Syntaxin-5 N-terminal, Sly1p-binding domain VQ PF05678.14 KFM26960.1 - 0.0075 15.7 0.2 0.019 14.5 0.2 1.7 1 0 0 1 1 1 1 VQ motif Syntaxin-18_N PF10496.9 KFM26960.1 - 0.11 12.8 0.1 0.46 10.8 0.0 2.0 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus Rcd1 PF04078.13 KFM26961.1 - 1.1e-122 408.4 0.0 1.2e-122 408.2 0.0 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Acyl_transf_1 PF00698.21 KFM26962.1 - 4.6e-26 92.1 1.3 6.4e-26 91.6 1.3 1.1 1 0 0 1 1 1 1 Acyl transferase domain DUF924 PF06041.11 KFM26963.1 - 2.5e-46 158.1 0.0 2.8e-46 157.9 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) eIF3m_C_helix PF18005.1 KFM26963.1 - 0.48 10.2 2.7 0.34 10.7 0.8 1.8 2 0 0 2 2 2 0 eIF3 subunit M, C-terminal helix AA_permease_2 PF13520.6 KFM26964.1 - 2.9e-60 204.3 48.5 4e-60 203.8 48.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFM26964.1 - 5.1e-14 51.7 38.8 7.3e-14 51.2 38.8 1.1 1 0 0 1 1 1 1 Amino acid permease THUMP PF02926.17 KFM26964.1 - 3.6e-08 33.6 0.0 6.3e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 THUMP domain DUF3381 PF11861.8 KFM26964.1 - 0.052 13.3 1.7 0.083 12.7 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) HlyE PF06109.13 KFM26964.1 - 4.7 6.4 4.1 0.74 9.1 0.1 1.7 2 0 0 2 2 2 0 Haemolysin E (HlyE) Tim17 PF02466.19 KFM26965.1 - 1.8e-29 102.3 9.0 2.4e-29 101.9 9.0 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Bacteriocin_IIc PF10439.9 KFM26965.1 - 0.0019 18.3 0.2 0.0019 18.3 0.2 2.4 3 0 0 3 3 3 1 Bacteriocin class II with double-glycine leader peptide Romo1 PF10247.9 KFM26965.1 - 0.035 14.5 2.4 0.035 14.5 2.4 2.7 2 1 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 ATP_bind_3 PF01171.20 KFM26966.1 - 1e-37 129.7 0.0 1.3e-35 122.8 0.0 2.2 1 1 0 1 1 1 1 PP-loop family RsdA_SigD_bd PF16751.5 KFM26966.1 - 0.1 12.9 0.0 0.1 12.9 0.0 2.5 3 1 0 3 3 3 0 Anti-sigma-D factor RsdA to sigma factor binding region EF-hand_1 PF00036.32 KFM26967.1 - 1.5e-13 49.2 7.7 5.2e-06 25.6 0.7 3.9 3 1 1 4 4 4 2 EF hand EF-hand_7 PF13499.6 KFM26967.1 - 3e-12 46.8 1.9 9.6e-06 26.0 0.0 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFM26967.1 - 1.8e-11 43.0 5.3 3.4e-05 23.4 0.3 3.8 4 1 1 5 5 5 2 EF-hand domain EF-hand_5 PF13202.6 KFM26967.1 - 7.4e-09 34.7 7.7 0.00022 20.6 0.2 3.3 3 1 1 4 4 4 2 EF hand EF-hand_8 PF13833.6 KFM26967.1 - 0.00012 21.9 5.3 0.13 12.1 2.9 3.0 2 1 0 2 2 2 2 EF-hand domain pair Dockerin_1 PF00404.18 KFM26967.1 - 0.056 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Dockerin type I domain DUF1251 PF06856.11 KFM26967.1 - 0.081 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1251) Glyco_tranf_2_4 PF13704.6 KFM26968.1 - 2.6e-07 31.0 0.2 3.4e-06 27.5 0.1 2.7 2 1 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 KFM26968.1 - 0.075 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 92 Sulfotransfer_3 PF13469.6 KFM26970.1 - 9.8e-17 62.1 0.1 1.5e-08 35.3 0.0 3.0 2 1 0 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 KFM26970.1 - 1.6e-11 44.2 0.0 2.4e-08 33.8 0.0 2.2 2 0 0 2 2 2 2 Sulfotransferase domain WD40 PF00400.32 KFM26971.1 - 1e-12 48.3 16.7 0.0028 18.4 0.1 6.8 7 1 0 7 7 6 4 WD domain, G-beta repeat U-box PF04564.15 KFM26971.1 - 2.7e-09 37.1 0.0 5.1e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 U-box domain ANAPC4_WD40 PF12894.7 KFM26971.1 - 1.6e-08 34.7 0.0 0.058 13.7 0.0 4.4 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_UBOX PF13445.6 KFM26971.1 - 3.2e-08 33.4 13.5 7.3e-08 32.3 13.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFM26971.1 - 6.2e-08 32.4 15.0 1.3e-07 31.4 15.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFM26971.1 - 2e-07 30.7 18.8 3.5e-07 29.9 18.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM26971.1 - 1.3e-06 28.1 18.4 2.5e-06 27.2 18.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM26971.1 - 2.3e-06 27.5 17.7 4.6e-06 26.5 17.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFM26971.1 - 3e-06 27.3 13.5 2.4e-05 24.4 13.8 2.2 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KFM26971.1 - 4.5e-06 26.9 19.7 4.5e-06 26.9 19.7 1.8 2 0 0 2 2 1 1 Ring finger domain Prok-RING_4 PF14447.6 KFM26971.1 - 0.00061 19.6 15.7 0.0017 18.2 15.8 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KFM26971.1 - 0.061 13.6 16.3 0.22 11.8 16.3 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_6 PF14835.6 KFM26971.1 - 0.26 11.2 9.7 1.1 9.2 9.7 2.0 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 KFM26971.1 - 0.51 10.2 16.3 2 8.2 11.5 2.4 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 KFM26971.1 - 1.6 9.0 16.2 0.64 10.2 13.2 1.9 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-Nse PF11789.8 KFM26971.1 - 1.9 8.4 10.8 3.8 7.4 10.8 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit CKS PF01111.19 KFM26972.1 - 7.5e-34 115.8 2.1 8.4e-34 115.7 2.1 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit DEAD PF00270.29 KFM26973.1 - 2.1e-43 148.1 0.0 4e-43 147.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM26973.1 - 3.9e-30 104.5 0.0 9.5e-30 103.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM26973.1 - 0.0011 19.0 0.0 0.0063 16.5 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-CCHC PF00098.23 KFM26973.1 - 0.0021 18.1 1.8 0.0039 17.2 1.8 1.5 1 0 0 1 1 1 1 Zinc knuckle SBF_like PF13593.6 KFM26973.1 - 0.23 10.7 0.0 0.33 10.2 0.0 1.1 1 0 0 1 1 1 0 SBF-like CPA transporter family (DUF4137) BING4CT PF08149.11 KFM26974.1 - 1.6e-29 101.5 0.0 1.7e-28 98.2 0.0 2.7 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.32 KFM26974.1 - 0.0013 19.5 4.9 1.6 9.7 0.0 4.2 5 0 0 5 5 5 2 WD domain, G-beta repeat TLD PF07534.16 KFM26975.1 - 2.8e-30 105.3 0.0 3.5e-30 105.0 0.0 1.1 1 0 0 1 1 1 1 TLD REV PF00424.18 KFM26975.1 - 0.08 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) NAP PF00956.18 KFM26976.1 - 3.3e-45 154.4 11.4 7.5e-35 120.4 2.6 2.6 2 1 1 3 3 2 2 Nucleosome assembly protein (NAP) ACP_syn_III_C PF08541.10 KFM26976.1 - 1.6e-36 124.4 0.5 4.8e-36 122.8 0.3 2.0 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 KFM26976.1 - 6e-31 106.1 0.5 6e-31 106.1 0.5 1.8 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 KFM26976.1 - 2.1e-05 24.0 0.1 5.5e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain ING PF12998.7 KFM26976.1 - 0.0057 17.2 0.0 0.015 15.9 0.0 1.6 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding Phage_Mu_Gam PF07352.12 KFM26976.1 - 0.012 15.5 0.5 0.028 14.3 0.5 1.5 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein Chal_sti_synt_C PF02797.15 KFM26976.1 - 0.039 13.9 0.0 0.07 13.1 0.0 1.4 1 0 0 1 1 1 0 Chalcone and stilbene synthases, C-terminal domain SDA1 PF05285.12 KFM26976.1 - 0.098 12.1 10.5 0.15 11.4 10.5 1.3 1 0 0 1 1 1 0 SDA1 TFIIF_alpha PF05793.12 KFM26976.1 - 0.12 11.0 11.8 0.19 10.3 11.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CobT PF06213.12 KFM26976.1 - 0.2 11.0 17.8 0.36 10.2 17.8 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Cwf_Cwc_15 PF04889.12 KFM26976.1 - 0.7 9.6 11.2 1.4 8.6 11.2 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nucleo_P87 PF07267.11 KFM26976.1 - 0.76 8.6 3.3 1.1 8.0 3.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 YL1 PF05764.13 KFM26976.1 - 0.86 9.7 14.6 1.6 8.8 14.6 1.4 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 KFM26976.1 - 4.8 5.3 11.5 7.1 4.8 11.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Flagellin_N PF00669.20 KFM26977.1 - 0.11 12.5 1.1 0.24 11.5 0.2 1.7 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region EF-1_beta_acid PF10587.9 KFM26977.1 - 1.6 9.2 5.5 3.5 8.2 5.5 1.5 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region WD40 PF00400.32 KFM26979.1 - 0.0027 18.5 0.5 2.2 9.3 0.1 3.9 4 0 0 4 4 4 1 WD domain, G-beta repeat Ank_2 PF12796.7 KFM26980.1 - 1.5e-13 51.1 0.6 1.8e-05 25.2 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFM26980.1 - 2.1e-09 36.8 8.6 0.24 12.1 0.4 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 KFM26980.1 - 3.6e-06 27.4 6.4 0.21 12.2 0.0 4.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFM26980.1 - 5.6e-06 26.5 8.7 0.074 13.4 0.0 5.1 5 0 0 5 5 5 1 Ankyrin repeats (many copies) zf-C3HC4 PF00097.25 KFM26980.1 - 2.8e-05 23.9 0.3 2.8e-05 23.9 0.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM26980.1 - 9.2e-05 22.7 1.2 9.2e-05 22.7 1.2 2.5 2 0 0 2 2 2 1 Ring finger domain Ank PF00023.30 KFM26980.1 - 0.00022 21.5 18.1 1.1 9.8 0.0 5.4 5 0 0 5 5 5 2 Ankyrin repeat zf-RING_UBOX PF13445.6 KFM26980.1 - 0.00054 19.9 0.4 0.00054 19.9 0.4 2.5 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFM26980.1 - 0.0011 18.9 1.2 0.0011 18.9 1.2 2.7 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFM26980.1 - 0.0037 17.4 1.2 0.0037 17.4 1.2 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KFM26980.1 - 0.009 15.9 0.8 0.009 15.9 0.8 2.4 2 1 0 2 2 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KFM26980.1 - 0.017 14.9 2.9 0.017 14.9 2.9 2.9 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KFM26980.1 - 0.046 13.5 1.6 0.046 13.5 1.6 1.9 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain Prim_Zn_Ribbon PF08273.12 KFM26980.1 - 0.3 11.4 0.2 0.3 11.4 0.2 2.5 3 0 0 3 3 2 0 Zinc-binding domain of primase-helicase Glyco_transf_21 PF13506.6 KFM26982.1 - 8.1e-15 54.7 0.0 2e-14 53.4 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KFM26982.1 - 2.7e-06 27.3 0.0 5.3e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KFM26982.1 - 0.0017 18.3 0.0 0.0025 17.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF1997 PF09366.10 KFM26983.1 - 2.8e-10 40.5 0.0 5.4e-10 39.6 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1997) DSPc PF00782.20 KFM26985.1 - 1.4e-20 73.5 0.0 2.1e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Gelsolin PF00626.22 KFM26985.1 - 0.00014 21.7 0.0 0.00026 20.8 0.0 1.4 1 0 0 1 1 1 1 Gelsolin repeat OrfB_Zn_ribbon PF07282.11 KFM26985.1 - 0.012 15.5 6.4 0.47 10.4 1.3 2.6 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Y_phosphatase PF00102.27 KFM26985.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Metallophos_C PF14008.6 KFM26986.1 - 0.0041 17.9 0.0 0.018 15.9 0.0 2.0 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 KFM26987.1 - 1.9e-19 70.0 0.0 5.2e-19 68.6 0.0 1.8 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 KFM26987.1 - 7e-11 43.0 0.3 1.4e-10 42.1 0.3 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase fn3_PAP PF17808.1 KFM26987.1 - 2e-08 34.4 0.1 6e-08 32.8 0.0 1.9 2 0 0 2 2 2 1 Fn3-like domain from Purple Acid Phosphatase VTC PF09359.10 KFM26988.1 - 2.1e-38 132.3 0.0 9.3e-19 67.9 0.0 2.2 1 1 1 2 2 2 2 VTC domain SPX PF03105.19 KFM26988.1 - 1.2e-19 71.5 11.1 3e-07 30.7 2.1 3.2 2 1 1 3 3 3 3 SPX domain DUF202 PF02656.15 KFM26988.1 - 3.6e-09 36.9 2.9 1.2e-08 35.2 2.9 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF202) CCDC154 PF15450.6 KFM26988.1 - 0.0097 14.5 0.2 0.014 14.0 0.2 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 154 K_channel_TID PF07941.11 KFM26988.1 - 1.8 9.1 3.8 0.78 10.2 0.7 1.9 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain DUF202 PF02656.15 KFM26990.1 - 1.6e-11 44.5 6.0 4.5e-11 43.0 3.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF4811 PF16069.5 KFM26990.1 - 0.066 13.1 0.5 0.066 13.1 0.5 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4811) Shugoshin_N PF07558.11 KFM26991.1 - 0.89 9.5 2.7 31 4.6 0.1 3.7 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region PI3K_P85_iSH2 PF16454.5 KFM26991.1 - 3.9 7.0 14.3 0.073 12.7 4.2 2.5 2 1 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Syntaxin-6_N PF09177.11 KFM26991.1 - 5.7 7.6 7.5 9 6.9 3.4 3.2 2 1 0 2 2 2 0 Syntaxin 6, N-terminal AMP-binding PF00501.28 KFM26994.1 - 1.1e-80 271.3 0.2 1.3e-80 271.1 0.2 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFM26994.1 - 2.5e-15 57.2 0.0 4.6e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Kinesin PF00225.23 KFM26995.1 - 4.9e-70 236.1 0.0 6e-45 153.6 0.0 2.2 1 1 1 2 2 2 2 Kinesin motor domain MoeA_N PF03453.17 KFM26995.1 - 1.3e-36 125.8 0.7 1.3e-36 125.8 0.7 2.3 2 0 0 2 2 2 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 KFM26995.1 - 7.9e-24 84.0 0.0 1.7e-23 82.9 0.0 1.6 1 0 0 1 1 1 1 Probable molybdopterin binding domain Microtub_bd PF16796.5 KFM26995.1 - 3.5e-23 82.2 0.0 9.1e-22 77.6 0.0 2.2 1 1 0 1 1 1 1 Microtubule binding MoeA_C PF03454.15 KFM26995.1 - 1.8e-10 40.8 0.0 7.3e-10 38.9 0.0 2.1 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) CC2-LZ PF16516.5 KFM26995.1 - 0.0084 16.4 2.3 0.0084 16.4 2.3 2.7 3 0 0 3 3 3 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator TrmO_C PF18389.1 KFM26995.1 - 0.032 14.4 0.1 0.46 10.6 0.0 2.6 2 0 0 2 2 2 0 TrmO C-terminal domain PRKG1_interact PF15898.5 KFM26995.1 - 8.3 7.4 7.4 43 5.1 2.3 3.1 2 1 1 4 4 4 0 cGMP-dependent protein kinase interacting domain zinc_ribbon_6 PF14599.6 KFM26997.1 - 3.6e-25 87.7 0.1 3.6e-25 87.7 0.1 1.4 2 0 0 2 2 2 1 Zinc-ribbon HypA PF01155.19 KFM26997.1 - 0.00063 19.7 2.1 0.00074 19.5 0.1 1.8 1 1 1 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 KFM26997.1 - 0.0014 18.6 5.5 0.042 13.9 5.5 2.1 1 1 0 1 1 1 1 Double zinc ribbon zinc_ribbon_10 PF10058.9 KFM26997.1 - 0.0036 17.0 3.7 0.055 13.2 0.3 2.3 2 0 0 2 2 2 1 Predicted integral membrane zinc-ribbon metal-binding protein CpXC PF14353.6 KFM26997.1 - 0.0039 17.2 0.4 0.0066 16.5 0.4 1.4 1 1 0 1 1 1 1 CpXC protein Ribosomal_L37e PF01907.19 KFM26997.1 - 0.013 15.7 3.1 0.024 14.8 3.1 1.5 1 0 0 1 1 1 0 Ribosomal protein L37e zf-RING_2 PF13639.6 KFM26997.1 - 0.029 14.7 1.0 0.029 14.7 1.0 2.3 2 1 0 2 2 2 0 Ring finger domain GATA PF00320.27 KFM26997.1 - 0.29 10.8 3.8 0.39 10.4 0.2 2.6 2 0 0 2 2 2 0 GATA zinc finger Zn-ribbon_8 PF09723.10 KFM26997.1 - 0.31 11.2 6.0 0.89 9.7 1.8 2.4 2 1 0 2 2 2 0 Zinc ribbon domain zf-C2H2 PF00096.26 KFM26997.1 - 1.8 9.2 7.0 5 7.8 0.1 2.7 2 1 0 2 2 2 0 Zinc finger, C2H2 type Rubredoxin_2 PF18073.1 KFM26997.1 - 4.2 7.2 9.9 2.8 7.7 3.4 3.0 2 1 0 2 2 2 0 Rubredoxin metal binding domain Zn_ribbon_SprT PF17283.2 KFM26997.1 - 7.5 6.5 12.4 4.8 7.2 1.6 2.6 2 1 0 2 2 2 0 SprT-like zinc ribbon domain Hemerythrin PF01814.23 KFM26998.1 - 5.9e-23 81.9 24.9 7.5e-11 42.8 3.7 4.7 3 1 1 4 4 4 4 Hemerythrin HHE cation binding domain zf-CHY PF05495.12 KFM26998.1 - 6.7e-18 65.0 21.9 6.7e-18 65.0 21.9 3.3 3 0 0 3 3 3 1 CHY zinc finger ABC_tran_CTD PF16326.5 KFM26998.1 - 0.042 14.1 0.8 0.15 12.3 0.8 1.9 1 0 0 1 1 1 0 ABC transporter C-terminal domain LTXXQ PF07813.12 KFM27000.1 - 0.0077 16.9 16.8 0.016 15.9 0.6 5.2 4 1 0 4 4 4 1 LTXXQ motif family protein tRNA-synt_1b PF00579.25 KFM27001.1 - 0.00021 20.7 0.0 0.0068 15.8 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) DUF5569 PF17729.1 KFM27001.1 - 0.17 11.7 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5569) BAT2_N PF07001.11 KFM27002.1 - 1.5e-07 32.1 6.8 1.5e-07 32.1 6.8 1.9 1 1 1 2 2 2 1 BAT2 N-terminus WD40 PF00400.32 KFM27003.1 - 1.6e-38 130.0 11.2 3.4e-09 37.2 0.1 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM27003.1 - 1.6e-09 37.9 0.3 0.0045 17.3 0.0 5.3 1 1 6 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFM27003.1 - 2.3e-06 26.8 0.1 0.25 10.2 0.0 4.1 2 2 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KFM27003.1 - 0.00059 18.7 0.0 0.47 9.1 0.0 3.0 1 1 1 3 3 3 2 Nup133 N terminal like Nup160 PF11715.8 KFM27003.1 - 0.0028 16.4 4.7 4 6.0 0.2 4.2 2 2 2 5 5 5 2 Nucleoporin Nup120/160 Hira PF07569.11 KFM27003.1 - 0.089 12.5 0.1 6.3 6.4 0.0 2.9 1 1 0 2 2 2 0 TUP1-like enhancer of split DUF2478 PF10649.9 KFM27003.1 - 0.11 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2478) Frtz PF11768.8 KFM27003.1 - 0.22 9.8 0.0 0.37 9.1 0.0 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Ehrlichia_rpt PF09528.10 KFM27004.1 - 0.063 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Ehrlichia tandem repeat (Ehrlichia_rpt) C2 PF00168.30 KFM27005.1 - 1.8e-21 76.3 0.5 9.5e-16 58.0 0.1 2.4 2 0 0 2 2 2 2 C2 domain SMP_LBD PF17047.5 KFM27005.1 - 1.4e-06 27.9 0.0 2.5e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain DivIC PF04977.15 KFM27005.1 - 0.053 13.3 17.2 0.41 10.5 1.9 3.7 3 0 0 3 3 3 0 Septum formation initiator Herpes_BLRF2 PF05812.12 KFM27005.1 - 0.14 12.3 5.5 0.81 9.8 0.1 3.5 2 1 1 3 3 3 0 Herpesvirus BLRF2 protein TSC22 PF01166.18 KFM27005.1 - 0.23 11.8 3.4 20 5.6 0.1 3.5 3 0 0 3 3 3 0 TSC-22/dip/bun family Fib_alpha PF08702.10 KFM27005.1 - 0.29 11.3 0.6 5.8 7.1 2.4 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family GAS PF13851.6 KFM27005.1 - 2.2 7.6 17.2 0.86 8.9 4.6 2.6 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding DUF4618 PF15397.6 KFM27005.1 - 2.5 7.5 8.4 4.5 6.6 8.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) CENP-F_leu_zip PF10473.9 KFM27005.1 - 7 6.7 19.2 80 3.3 7.9 3.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UPF0047 PF01894.17 KFM27008.1 - 2.1e-39 134.2 0.0 2.5e-39 134.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Pyr_redox_2 PF07992.14 KFM27010.1 - 2.9e-47 161.3 0.7 3.5e-47 161.1 0.7 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFM27010.1 - 1.4e-14 54.4 1.0 1.4e-13 51.2 0.4 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFM27010.1 - 6.9e-05 22.2 0.0 0.0001 21.7 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFM27010.1 - 0.00036 20.2 2.5 0.45 10.0 0.0 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KFM27010.1 - 0.0062 15.4 0.4 0.08 11.8 0.0 2.2 2 0 0 2 2 2 1 Tryptophan halogenase Reductase_C PF14759.6 KFM27010.1 - 0.015 15.9 0.0 0.035 14.7 0.0 1.6 1 0 0 1 1 1 0 Reductase C-terminal NAD_binding_7 PF13241.6 KFM27010.1 - 0.098 13.1 0.0 0.26 11.8 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 KFM27010.1 - 0.13 11.8 0.3 0.19 11.3 0.3 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_9 PF13454.6 KFM27010.1 - 0.2 11.6 3.5 2.2 8.2 0.0 3.1 2 1 1 3 3 3 0 FAD-NAD(P)-binding GIDA PF01134.22 KFM27010.1 - 0.99 8.4 4.7 12 4.8 0.6 2.8 2 1 1 3 3 3 0 Glucose inhibited division protein A Chloroa_b-bind PF00504.21 KFM27011.1 - 3.5e-44 151.2 0.0 4.4e-44 150.8 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Polyketide_cyc PF03364.20 KFM27012.1 - 2.9e-23 82.5 0.6 3.1e-13 50.1 0.1 2.4 2 0 0 2 2 2 2 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 KFM27012.1 - 3.7e-09 37.0 6.6 0.00037 20.8 0.2 2.7 2 0 0 2 2 2 2 Polyketide cyclase / dehydrase and lipid transport LSM PF01423.22 KFM27013.1 - 4.5e-09 35.9 0.0 7e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 LSM domain NAD_binding_2 PF03446.15 KFM27013.1 - 0.11 12.6 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase PRA-CH PF01502.18 KFM27014.1 - 2.6e-22 78.4 0.0 5.2e-22 77.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase zf-CCHC PF00098.23 KFM27014.1 - 4.8e-16 58.0 32.0 6.7e-08 32.3 3.0 4.9 4 0 0 4 4 4 4 Zinc knuckle PRA-PH PF01503.17 KFM27014.1 - 1.5e-10 41.4 0.1 2.6e-10 40.6 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase zf-CCHC_3 PF13917.6 KFM27014.1 - 4.2e-05 23.4 17.8 0.022 14.7 0.8 4.8 4 1 1 5 5 5 3 Zinc knuckle zf-CCHC_4 PF14392.6 KFM27014.1 - 0.00036 20.2 24.7 0.16 11.7 0.4 4.4 4 0 0 4 4 4 4 Zinc knuckle MazG PF03819.17 KFM27014.1 - 0.0059 16.8 0.1 0.0099 16.0 0.1 1.3 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain NOG1_N PF17835.1 KFM27015.1 - 5.3e-29 101.3 0.2 5.9e-29 101.1 0.2 1.0 1 0 0 1 1 1 1 NOG1 N-terminal helical domain NOG1 PF06858.14 KFM27016.1 - 2e-19 69.1 0.0 4.1e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 KFM27016.1 - 8.7e-16 58.0 0.0 1.4e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFM27016.1 - 4.8e-09 35.9 0.0 7.9e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 KFM27016.1 - 0.02 15.3 0.1 0.18 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 KFM27016.1 - 0.037 13.9 1.4 0.17 11.8 0.6 2.4 2 2 0 2 2 2 0 RsgA GTPase MeaB PF03308.16 KFM27016.1 - 0.14 11.2 0.0 7.7 5.4 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 KFM27016.1 - 0.14 12.7 0.0 0.22 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KFM27016.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.5 1 1 0 1 1 1 0 NACHT domain AAA_15 PF13175.6 KFM27016.1 - 0.31 10.7 0.0 0.44 10.2 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Mog1 PF04603.12 KFM27018.1 - 1.6e-29 103.0 0.0 2.1e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Beta-lactamase PF00144.24 KFM27019.1 - 8.8e-20 71.2 7.4 1e-18 67.7 7.4 2.2 1 1 0 1 1 1 1 Beta-lactamase Methyltransf_11 PF08241.12 KFM27020.1 - 8.8e-37 125.7 0.4 1.3e-17 64.2 0.0 3.3 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_25 PF13649.6 KFM27020.1 - 3.3e-34 117.5 0.6 2.1e-16 60.4 0.0 3.3 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.6 KFM27020.1 - 9.5e-26 90.4 0.0 4.4e-14 52.6 0.0 3.2 2 2 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 KFM27020.1 - 3e-24 85.7 0.0 2.2e-15 56.9 0.0 2.6 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KFM27020.1 - 4.7e-22 78.6 0.1 2.4e-12 47.5 0.0 3.3 3 0 0 3 3 3 2 Methyltransferase domain Ubie_methyltran PF01209.18 KFM27020.1 - 7.6e-13 48.3 0.0 1.9e-05 24.1 0.0 2.4 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KFM27020.1 - 4.4e-10 39.3 0.0 2.2e-08 33.7 0.0 3.2 3 1 0 3 3 3 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 KFM27020.1 - 4.8e-08 32.5 0.0 9e-05 21.9 0.0 3.0 2 1 0 2 2 2 2 O-methyltransferase domain NodS PF05401.11 KFM27020.1 - 1.6e-06 27.9 0.0 0.00071 19.2 0.0 3.1 3 1 0 3 3 3 1 Nodulation protein S (NodS) PCMT PF01135.19 KFM27020.1 - 2.3e-06 27.5 0.0 0.0012 18.6 0.0 2.2 2 0 0 2 2 2 2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.14 KFM27020.1 - 3.1e-06 26.7 0.0 0.0016 17.9 0.0 2.4 2 0 0 2 2 2 2 Tellurite resistance protein TehB CheR PF01739.18 KFM27020.1 - 4.1e-06 26.4 0.0 1.2 8.6 0.0 4.1 4 0 0 4 4 4 1 CheR methyltransferase, SAM binding domain Methyltransf_32 PF13679.6 KFM27020.1 - 6e-06 26.3 0.0 0.0028 17.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_PK PF05891.12 KFM27020.1 - 1.5e-05 24.6 0.0 0.00014 21.5 0.0 2.2 2 1 0 2 2 2 1 AdoMet dependent proline di-methyltransferase RrnaAD PF00398.20 KFM27020.1 - 0.00016 20.9 0.0 0.0037 16.4 0.0 2.1 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase TPMT PF05724.11 KFM27020.1 - 0.00091 18.9 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) MTS PF05175.14 KFM27020.1 - 0.0011 18.6 0.2 0.017 14.7 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KFM27020.1 - 0.0024 17.4 0.0 3.3 7.1 0.0 2.7 3 0 0 3 3 3 2 Putative methyltransferase MetW PF07021.12 KFM27020.1 - 0.003 17.2 0.0 0.014 15.0 0.0 1.9 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW FtsJ PF01728.19 KFM27020.1 - 0.0036 17.4 0.0 3.2 7.8 0.0 2.5 2 0 0 2 2 2 2 FtsJ-like methyltransferase Met_10 PF02475.16 KFM27020.1 - 0.017 14.9 0.0 0.18 11.5 0.0 2.1 2 0 0 2 2 2 0 Met-10+ like-protein Methyltransf_15 PF09445.10 KFM27020.1 - 0.033 13.8 0.1 0.079 12.5 0.0 1.6 2 0 0 2 2 1 0 RNA cap guanine-N2 methyltransferase DOT1 PF08123.13 KFM27020.1 - 0.035 13.6 0.1 0.15 11.6 0.0 1.9 2 0 0 2 2 2 0 Histone methylation protein DOT1 N2227 PF07942.12 KFM27020.1 - 0.059 12.5 0.2 0.12 11.5 0.0 1.5 2 0 0 2 2 2 0 N2227-like protein PMT2_N PF17987.1 KFM27020.1 - 0.096 12.9 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Phosphoethanolamine N-methyltransferase 2 N-terminal Methyltransf_9 PF08003.11 KFM27020.1 - 0.1 11.5 0.0 0.55 9.1 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1698) DUF938 PF06080.12 KFM27020.1 - 0.21 11.3 0.0 0.5 10.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Acyltransferase PF01553.21 KFM27021.1 - 6.1e-14 51.8 0.0 1.3e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase AAA_6 PF12774.7 KFM27022.1 - 1.5e-140 467.8 0.0 3.4e-140 466.7 0.0 1.6 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA_8 PF12780.7 KFM27022.1 - 2e-77 260.1 0.0 6.1e-76 255.2 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KFM27022.1 - 1.5e-72 243.3 0.1 1.9e-71 239.7 0.1 2.7 2 0 0 2 2 2 1 ATP-binding dynein motor region DHC_N1 PF08385.12 KFM27022.1 - 7.5e-69 232.8 2.5 1.8e-48 165.6 0.0 4.6 3 1 1 4 4 4 2 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 KFM27022.1 - 3.7e-68 230.5 1.8 3.7e-68 230.5 1.8 3.8 3 2 1 4 4 3 1 Dynein heavy chain, N-terminal region 2 AAA_7 PF12775.7 KFM27022.1 - 2.3e-58 196.7 0.0 7.8e-52 175.4 0.0 3.6 3 0 0 3 3 3 3 P-loop containing dynein motor region Dynein_C PF18199.1 KFM27022.1 - 9.7e-53 179.4 0.0 5.2e-52 177.0 0.0 2.4 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 KFM27022.1 - 4.9e-42 143.5 0.0 1e-41 142.5 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 KFM27022.1 - 1.4e-41 142.7 8.8 1.4e-41 142.7 8.8 1.8 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 KFM27022.1 - 2.4e-37 127.6 0.5 1.7e-33 115.3 0.0 4.9 4 0 0 4 4 3 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 KFM27022.1 - 7.2e-26 90.8 0.0 3e-11 43.5 0.0 5.4 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 KFM27022.1 - 8.5e-25 87.3 0.0 1.1e-23 83.8 0.0 3.0 4 0 0 4 4 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 KFM27022.1 - 3e-14 53.5 3.1 0.01 16.1 0.1 5.8 5 0 0 5 5 4 4 AAA domain AAA PF00004.29 KFM27022.1 - 1.2e-12 48.4 0.1 0.008 16.6 0.0 5.3 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KFM27022.1 - 9.4e-08 32.7 0.3 1 9.9 0.0 4.9 4 0 0 4 4 4 2 AAA domain AAA_lid_1 PF17857.1 KFM27022.1 - 5e-07 29.9 0.0 1.5e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KFM27022.1 - 2.2e-06 28.2 24.8 0.0041 17.5 0.1 7.5 8 0 0 8 8 4 3 AAA ATPase domain AAA_28 PF13521.6 KFM27022.1 - 2.8e-06 27.7 0.9 0.46 10.7 0.0 4.9 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 KFM27022.1 - 4.5e-06 26.9 11.7 0.065 13.4 0.0 5.6 6 0 0 6 6 5 2 AAA domain AAA_24 PF13479.6 KFM27022.1 - 5.2e-05 23.0 0.7 0.73 9.5 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 KFM27022.1 - 6.6e-05 23.3 3.0 0.7 10.2 0.1 4.2 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 KFM27022.1 - 0.00021 21.6 0.7 11 6.5 0.0 3.7 3 0 0 3 3 3 0 RNA helicase AAA_29 PF13555.6 KFM27022.1 - 0.00049 19.8 2.5 0.62 9.9 0.0 4.1 4 0 0 4 4 4 1 P-loop containing region of AAA domain IstB_IS21 PF01695.17 KFM27022.1 - 0.00063 19.5 0.2 0.82 9.4 0.0 3.7 3 0 0 3 3 3 1 IstB-like ATP binding protein ERM PF00769.19 KFM27022.1 - 0.00069 19.5 8.5 0.00069 19.5 8.5 4.3 4 0 0 4 4 4 1 Ezrin/radixin/moesin family NACHT PF05729.12 KFM27022.1 - 0.00093 19.1 2.8 0.22 11.4 0.0 4.0 3 0 0 3 3 2 1 NACHT domain AAA_30 PF13604.6 KFM27022.1 - 0.0021 17.8 0.1 0.0021 17.8 0.1 6.1 7 0 0 7 7 5 2 AAA domain ATPase PF06745.13 KFM27022.1 - 0.0067 15.8 0.3 0.027 13.8 0.0 2.2 2 0 0 2 2 1 1 KaiC AAA_25 PF13481.6 KFM27022.1 - 0.0079 15.8 8.6 0.34 10.5 0.1 4.9 4 0 0 4 4 4 1 AAA domain Roc PF08477.13 KFM27022.1 - 0.022 15.0 1.6 4.3 7.6 0.0 3.1 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 KFM27022.1 - 0.022 14.2 0.0 8 5.8 0.0 2.8 2 0 0 2 2 2 0 Bacterial TniB protein RsgA_GTPase PF03193.16 KFM27022.1 - 0.023 14.6 3.7 2.7 7.9 0.1 4.0 4 0 0 4 4 4 0 RsgA GTPase AAA_14 PF13173.6 KFM27022.1 - 0.027 14.5 0.0 1.5 8.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain Ploopntkinase3 PF18751.1 KFM27022.1 - 0.068 13.1 0.3 14 5.6 0.1 3.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 MMR_HSR1 PF01926.23 KFM27022.1 - 0.12 12.5 3.4 1.3 9.1 0.0 3.3 3 0 0 3 3 2 0 50S ribosome-binding GTPase SRP54 PF00448.22 KFM27022.1 - 0.16 11.6 8.4 0.96 9.0 0.0 4.2 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain Mg_chelatase PF01078.21 KFM27022.1 - 0.23 10.8 7.4 5.3 6.4 0.1 3.9 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KFM27022.1 - 0.23 11.1 6.0 8.6 6.0 0.1 4.0 5 0 0 5 5 4 0 Sigma-54 interaction domain PduV-EutP PF10662.9 KFM27022.1 - 0.27 11.0 1.3 18 5.0 0.0 3.3 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF4349 PF14257.6 KFM27022.1 - 0.5 9.8 22.1 0.21 11.0 1.3 3.3 3 0 0 3 3 2 0 Domain of unknown function (DUF4349) ATP_bind_1 PF03029.17 KFM27022.1 - 0.53 10.0 13.1 4.3 7.0 0.0 4.2 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein DUF2075 PF09848.9 KFM27022.1 - 0.59 9.3 4.1 11 5.1 0.0 2.9 3 0 0 3 3 2 0 Uncharacterized conserved protein (DUF2075) Spc7 PF08317.11 KFM27022.1 - 1.2 7.9 31.1 0.0022 16.9 3.6 4.5 4 0 0 4 4 4 0 Spc7 kinetochore protein ABC_tran PF00005.27 KFM27022.1 - 1.5 9.3 13.8 1.2 9.6 0.1 4.9 6 0 0 6 6 3 0 ABC transporter DUF815 PF05673.13 KFM27022.1 - 2.2 7.4 7.5 0.36 10.0 0.1 3.2 4 0 0 4 4 3 0 Protein of unknown function (DUF815) Parvo_NS1 PF01057.17 KFM27022.1 - 2.5 7.1 5.5 1.1 8.3 0.1 2.8 4 0 0 4 4 2 0 Parvovirus non-structural protein NS1 cobW PF02492.19 KFM27022.1 - 2.8 7.5 6.2 9.3 5.8 0.1 3.2 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Mei5 PF10376.9 KFM27022.1 - 3.5 7.5 8.2 0.16 11.8 1.1 2.2 2 0 0 2 2 2 0 Double-strand recombination repair protein TsaE PF02367.17 KFM27022.1 - 4.5 7.3 9.5 18 5.4 0.1 3.7 4 0 0 4 4 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF4082 PF13313.6 KFM27023.1 - 0.12 12.4 0.1 0.24 11.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4082) Thioredoxin PF00085.20 KFM27024.1 - 4.5e-19 68.3 0.2 9.8e-17 60.8 0.2 2.1 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KFM27024.1 - 0.0067 16.7 0.0 0.0094 16.3 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KFM27024.1 - 0.016 15.7 0.1 0.024 15.1 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin-like domain AhpC-TSA PF00578.21 KFM27024.1 - 0.026 14.4 0.0 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family Redoxin PF08534.10 KFM27024.1 - 0.034 13.9 0.0 0.036 13.8 0.0 1.2 1 0 0 1 1 1 0 Redoxin Thioredoxin_7 PF13899.6 KFM27024.1 - 0.036 14.2 0.0 0.084 13.1 0.0 1.6 2 0 0 2 2 2 0 Thioredoxin-like TPR_1 PF00515.28 KFM27026.1 - 1.9e-46 154.1 21.7 4.3e-07 29.5 0.0 11.2 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_11 PF13414.6 KFM27026.1 - 5e-40 134.9 26.2 1.6e-06 27.6 0.0 9.9 5 2 5 10 10 10 9 TPR repeat TPR_2 PF07719.17 KFM27026.1 - 1.7e-39 130.7 26.1 3.9e-06 26.6 0.0 11.1 11 0 0 11 11 11 8 Tetratricopeptide repeat Glyco_transf_41 PF13844.6 KFM27026.1 - 4.1e-37 127.7 0.0 1.2e-17 63.5 0.0 3.1 2 1 1 3 3 3 3 Glycosyl transferase family 41 TPR_8 PF13181.6 KFM27026.1 - 3.8e-36 120.3 10.0 3.1e-05 23.9 0.0 10.5 11 0 0 11 11 10 7 Tetratricopeptide repeat TPR_17 PF13431.6 KFM27026.1 - 3.4e-30 102.2 20.7 0.00015 21.9 0.2 11.0 10 1 1 11 11 11 6 Tetratricopeptide repeat TPR_16 PF13432.6 KFM27026.1 - 8.5e-29 99.9 35.5 8.8e-06 26.3 0.2 7.8 4 2 4 8 8 8 8 Tetratricopeptide repeat TPR_12 PF13424.6 KFM27026.1 - 3.8e-26 91.2 32.9 1.9e-07 31.3 0.0 7.9 4 3 1 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 KFM27026.1 - 8.4e-23 79.1 34.4 0.0008 20.0 0.5 10.6 3 3 7 10 10 10 7 Tetratricopeptide repeat TPR_7 PF13176.6 KFM27026.1 - 1.2e-20 71.9 23.6 0.00013 21.7 0.0 9.5 11 0 0 11 11 9 5 Tetratricopeptide repeat TPR_19 PF14559.6 KFM27026.1 - 7.7e-18 64.8 30.7 1.7e-05 25.2 0.0 8.4 4 3 4 9 9 9 5 Tetratricopeptide repeat TPR_6 PF13174.6 KFM27026.1 - 7.6e-15 54.5 7.9 1.5 9.6 0.0 8.8 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_10 PF13374.6 KFM27026.1 - 4.5e-09 35.9 50.0 0.00071 19.4 0.6 10.3 12 1 0 12 12 10 4 Tetratricopeptide repeat TPR_4 PF07721.14 KFM27026.1 - 6.3e-07 29.4 27.4 0.078 13.6 3.9 8.5 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFM27026.1 - 6.3e-07 29.4 29.4 0.00021 21.4 0.4 6.7 4 1 1 6 6 6 3 Tetratricopeptide repeat EST1_DNA_bind PF10373.9 KFM27026.1 - 8.8e-06 25.4 3.1 0.00014 21.5 0.2 2.7 2 1 1 3 3 3 1 Est1 DNA/RNA binding domain TPR_MalT PF17874.1 KFM27026.1 - 0.00019 20.9 16.5 0.032 13.6 0.1 4.3 2 1 2 4 4 4 3 MalT-like TPR region TPR_15 PF13429.6 KFM27026.1 - 0.0002 20.7 13.8 2.2 7.4 1.6 6.5 2 2 4 6 6 6 1 Tetratricopeptide repeat TPR_20 PF14561.6 KFM27026.1 - 0.00065 20.0 12.5 0.16 12.3 0.1 5.4 5 1 0 5 5 5 2 Tetratricopeptide repeat Coatomer_E PF04733.14 KFM27026.1 - 0.0014 18.1 0.3 0.03 13.7 0.0 2.7 1 1 3 4 4 4 2 Coatomer epsilon subunit NARP1 PF12569.8 KFM27026.1 - 0.016 14.2 0.0 15 4.4 0.0 3.3 3 0 0 3 3 3 0 NMDA receptor-regulated protein 1 TPR_21 PF09976.9 KFM27026.1 - 0.019 14.7 6.2 53 3.5 0.1 5.6 5 1 1 6 6 6 0 Tetratricopeptide repeat-like domain DUF1824 PF08854.10 KFM27026.1 - 0.11 12.4 1.3 1.6 8.7 0.0 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF1824) Wzy_C_2 PF11846.8 KFM27026.1 - 0.2 11.6 5.3 0.53 10.2 0.1 3.1 1 1 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal FAT PF02259.23 KFM27026.1 - 0.27 10.4 0.0 20 4.3 0.0 2.5 2 1 0 2 2 2 0 FAT domain ANAPC3 PF12895.7 KFM27026.1 - 0.33 11.2 17.1 1.9 8.8 0.1 5.2 3 3 3 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 KFM27026.1 - 1.6 9.2 26.0 1.1 9.6 0.4 5.0 2 2 2 5 5 5 0 Bacterial transcriptional activator domain TPR_5 PF12688.7 KFM27026.1 - 5.5 7.3 13.4 6.6 7.0 0.0 4.8 3 1 1 5 5 5 0 Tetratrico peptide repeat AATF-Che1 PF13339.6 KFM27027.1 - 9.3e-20 71.7 1.0 1.4e-19 71.1 0.2 1.7 2 0 0 2 2 2 1 Apoptosis antagonizing transcription factor TRAUB PF08164.12 KFM27027.1 - 4.1e-18 65.7 0.2 1.1e-17 64.3 0.2 1.8 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal DUF1771 PF08590.10 KFM27027.1 - 0.054 13.9 1.0 0.16 12.3 1.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) Importin_rep_4 PF18808.1 KFM27028.1 - 1.6e-19 70.0 2.2 2.7e-14 53.2 0.0 5.2 6 0 0 6 6 4 2 Importin repeat HEAT_EZ PF13513.6 KFM27028.1 - 3.7e-15 56.0 55.7 1.5e-05 25.4 0.8 15.1 12 4 6 18 18 16 4 HEAT-like repeat HEAT PF02985.22 KFM27028.1 - 2.3e-14 52.2 36.5 0.0044 17.1 0.2 13.0 14 0 0 14 14 14 4 HEAT repeat HEAT_2 PF13646.6 KFM27028.1 - 3.6e-14 52.9 26.5 4.3e-07 30.2 0.4 10.7 6 2 5 11 11 11 3 HEAT repeats DUF3385 PF11865.8 KFM27028.1 - 3.9e-09 36.6 0.0 0.2 11.6 0.0 4.6 5 0 0 5 5 5 3 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.7 KFM27028.1 - 5.9e-08 33.2 0.0 0.19 12.4 0.0 5.3 6 1 1 7 7 4 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 KFM27028.1 - 1.3e-06 27.8 1.6 0.053 12.6 0.1 4.8 5 1 1 6 6 6 2 RNAPII transcription regulator C-terminal RIX1 PF08167.12 KFM27028.1 - 5.2e-05 23.1 0.3 3.1 7.5 0.0 3.8 2 1 1 3 3 3 2 rRNA processing/ribosome biogenesis IFRD PF05004.13 KFM27028.1 - 8.6e-05 21.8 4.6 0.46 9.5 0.2 3.6 2 1 1 3 3 3 3 Interferon-related developmental regulator (IFRD) Adaptin_N PF01602.20 KFM27028.1 - 0.00028 19.6 0.1 0.022 13.3 0.0 3.4 1 1 2 3 3 3 1 Adaptin N terminal region ParcG PF10274.9 KFM27028.1 - 0.00044 20.4 0.1 5.6 7.0 0.1 4.5 5 1 1 6 6 6 1 Parkin co-regulated protein Cnd1 PF12717.7 KFM27028.1 - 0.00051 20.1 0.2 0.11 12.5 0.0 3.8 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 KFM27028.1 - 0.0025 17.8 9.5 1.1 9.4 0.0 5.6 5 0 0 5 5 4 2 Armadillo/beta-catenin-like repeat Tti2 PF10521.9 KFM27028.1 - 0.0058 16.2 0.0 4.7 6.7 0.0 4.3 3 1 0 3 3 3 1 Tti2 family Importin_rep_6 PF18829.1 KFM27028.1 - 0.0087 16.2 0.0 2.6 8.2 0.0 4.0 4 0 0 4 4 3 1 Importin repeat 6 V-ATPase_H_C PF11698.8 KFM27028.1 - 0.031 14.4 0.0 0.91 9.7 0.0 2.9 2 0 0 2 2 2 0 V-ATPase subunit H DUF4042 PF13251.6 KFM27028.1 - 0.049 13.3 0.8 1.5 8.5 0.0 3.3 3 0 0 3 3 2 0 Domain of unknown function (DUF4042) DRIM PF07539.12 KFM27028.1 - 0.083 11.2 1.4 2.5 6.3 1.2 3.2 2 1 0 2 2 2 0 Down-regulated in metastasis DUF577 PF04510.12 KFM27028.1 - 0.11 12.4 0.0 0.35 10.8 0.0 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF577) MMS19_N PF14500.6 KFM27028.1 - 0.15 11.6 2.7 1.3 8.6 0.2 3.5 4 1 1 5 5 5 0 Dos2-interacting transcription regulator of RNA-Pol-II TipAS PF07739.13 KFM27028.1 - 0.94 10.0 9.8 17 6.0 0.1 5.5 7 0 0 7 7 6 0 TipAS antibiotic-recognition domain DUF5334 PF17268.2 KFM27028.1 - 3.2 8.1 4.4 20 5.6 0.3 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5334) Pkinase PF00069.25 KFM27029.1 - 5.9e-55 186.5 0.0 3.2e-40 138.2 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFM27029.1 - 1.6e-39 135.8 0.0 1.7e-27 96.4 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KFM27029.1 - 0.0055 16.1 0.0 0.016 14.6 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Arm PF00514.23 KFM27030.1 - 0.05 13.7 2.3 14 5.9 0.2 4.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat UCH PF00443.29 KFM27031.1 - 6.9e-27 94.6 0.0 1e-26 94.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFM27031.1 - 2.7e-10 40.3 0.0 5.2e-10 39.4 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 KFM27031.1 - 0.02 14.4 0.2 0.96 8.9 0.1 2.7 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase CDC45 PF02724.14 KFM27032.1 - 2.6e-112 376.2 2.4 2.6e-111 373.0 2.4 2.2 1 1 0 1 1 1 1 CDC45-like protein Brix PF04427.18 KFM27033.1 - 8.6e-37 127.1 0.2 1.1e-36 126.8 0.2 1.1 1 0 0 1 1 1 1 Brix domain Ribosomal_L29 PF00831.23 KFM27034.1 - 1.2e-13 50.7 1.0 1.7e-13 50.3 1.0 1.2 1 0 0 1 1 1 1 Ribosomal L29 protein PLRV_ORF5 PF01690.17 KFM27034.1 - 0.0097 14.7 0.1 0.0097 14.7 0.1 1.0 1 0 0 1 1 1 1 Potato leaf roll virus readthrough protein DUF1192 PF06698.11 KFM27034.1 - 0.025 14.6 4.1 0.95 9.6 0.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) WHEP-TRS PF00458.20 KFM27034.1 - 0.21 11.8 3.9 7.3 6.8 0.6 2.6 1 1 1 2 2 2 0 WHEP-TRS domain Peptidase_M41 PF01434.18 KFM27035.1 - 1.7e-32 112.8 0.0 2.5e-32 112.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KFM27035.1 - 6.1e-18 65.5 0.0 1.2e-17 64.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFM27035.1 - 2.6e-09 36.7 0.1 7.2e-09 35.3 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain E1_dh PF00676.20 KFM27036.1 - 1.4e-109 365.7 0.3 1.8e-109 365.3 0.3 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KFM27036.1 - 0.00041 20.2 2.9 0.00044 20.1 0.8 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 KFM27036.1 - 0.0013 18.1 0.1 0.0022 17.2 0.1 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase BMC PF00936.19 KFM27036.1 - 0.097 12.7 2.2 5.2 7.1 0.0 3.0 3 0 0 3 3 3 0 BMC domain Thioredoxin PF00085.20 KFM27037.1 - 8.2e-31 106.1 0.0 1.2e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KFM27037.1 - 2.3e-08 34.4 0.1 8e-07 29.5 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KFM27037.1 - 2e-06 28.0 0.0 0.0002 21.6 0.0 2.3 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.6 KFM27037.1 - 3.2e-06 26.9 0.0 4.5e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 KFM27037.1 - 0.0013 18.6 0.0 0.0019 18.1 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Redoxin PF08534.10 KFM27037.1 - 0.008 15.9 0.0 0.064 13.0 0.0 1.9 1 1 1 2 2 2 1 Redoxin AhpC-TSA PF00578.21 KFM27037.1 - 0.0087 16.0 0.0 0.21 11.5 0.0 2.0 1 1 1 2 2 2 1 AhpC/TSA family HyaE PF07449.11 KFM27037.1 - 0.011 15.6 0.0 0.027 14.4 0.0 1.7 1 1 1 2 2 2 0 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.6 KFM27037.1 - 0.013 15.7 0.0 0.036 14.3 0.0 1.8 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_3 PF13192.6 KFM27037.1 - 0.029 14.4 0.0 0.049 13.7 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin domain OST3_OST6 PF04756.13 KFM27037.1 - 0.18 11.1 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family VCBS PF13517.6 KFM27038.1 - 4.8e-07 30.3 3.5 0.017 15.7 0.0 4.2 3 0 0 3 3 3 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 KFM27038.1 - 4.9e-07 29.8 10.1 0.00055 20.0 0.1 3.7 3 0 0 3 3 3 2 FG-GAP repeat PQQ_2 PF13360.6 KFM27038.1 - 0.085 12.4 0.0 1.9 8.0 0.0 2.4 3 0 0 3 3 3 0 PQQ-like domain EF-hand_5 PF13202.6 KFM27038.1 - 3.5 7.3 5.4 9.4 5.9 0.2 2.8 3 0 0 3 3 3 0 EF hand HlyIII PF03006.20 KFM27039.1 - 1.5e-06 28.1 12.0 1.1e-05 25.3 12.0 1.9 1 1 0 1 1 1 1 Haemolysin-III related DUF308 PF03729.13 KFM27039.1 - 0.78 10.1 9.3 0.51 10.7 3.4 2.7 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) TMEM208_SND2 PF05620.11 KFM27039.1 - 0.9 9.3 2.3 0.98 9.2 0.7 1.8 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 FAE1_CUT1_RppA PF08392.12 KFM27040.1 - 4.9e-117 390.4 0.0 6e-117 390.1 0.0 1.1 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.10 KFM27040.1 - 6.1e-09 35.9 0.0 2.1e-08 34.2 0.0 1.9 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Chal_sti_synt_C PF02797.15 KFM27040.1 - 9.7e-06 25.6 0.0 1.6e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain ACP_syn_III PF08545.10 KFM27040.1 - 8.2e-05 22.4 0.0 0.00017 21.4 0.0 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Chal_sti_synt_N PF00195.19 KFM27040.1 - 0.00014 21.4 0.2 0.00024 20.6 0.2 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Tfb4 PF03850.14 KFM27041.1 - 4.8e-48 164.0 0.0 2.5e-46 158.4 0.0 2.2 1 1 0 1 1 1 1 Transcription factor Tfb4 RED_N PF07808.13 KFM27041.1 - 9.3e-40 136.7 0.2 4.2e-39 134.5 0.0 2.0 2 1 0 2 2 2 1 RED-like protein N-terminal region RED_C PF07807.11 KFM27041.1 - 6.5e-08 33.0 1.1 1.7e-07 31.7 1.1 1.7 1 0 0 1 1 1 1 RED-like protein C-terminal region Glyco_transf_8 PF01501.20 KFM27042.1 - 7e-05 22.5 0.0 0.049 13.2 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 8 Nucleotid_trans PF03407.16 KFM27042.1 - 0.011 15.8 0.0 0.015 15.3 0.0 1.2 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase TPR_2 PF07719.17 KFM27044.1 - 1.4e-13 49.8 2.3 5e-06 26.2 0.4 3.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFM27044.1 - 1.8e-12 46.8 3.4 1.9e-10 40.3 0.1 2.4 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.28 KFM27044.1 - 1.7e-09 37.1 0.4 0.00011 21.9 0.0 2.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFM27044.1 - 1.4e-08 34.5 1.5 1.6e-06 28.1 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFM27044.1 - 1.2e-07 32.2 7.9 1.2e-07 32.2 7.9 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFM27044.1 - 1.1e-06 29.0 6.7 2.1e-06 28.2 6.7 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFM27044.1 - 6e-06 26.7 13.2 0.0014 19.3 5.6 3.2 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFM27044.1 - 2.5e-05 24.0 0.2 0.084 12.9 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFM27044.1 - 4e-05 23.7 6.2 8e-05 22.7 6.2 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFM27044.1 - 0.00043 20.3 0.0 0.38 11.1 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFM27044.1 - 0.0012 19.1 8.2 0.42 10.9 0.0 2.6 2 1 1 3 3 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM27044.1 - 0.096 12.9 0.5 0.23 11.7 0.2 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 KFM27044.1 - 0.1 12.7 0.4 0.34 11.0 0.2 1.8 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.6 KFM27044.1 - 0.3 11.4 5.2 0.25 11.7 2.7 2.2 2 1 0 2 2 2 0 Tetratricopeptide repeat MMR_HSR1 PF01926.23 KFM27046.1 - 3.7e-05 23.8 0.0 0.00014 21.9 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFM27046.1 - 0.035 14.0 0.0 0.15 11.9 0.0 1.8 1 1 0 1 1 1 0 RsgA GTPase TruB_C PF09142.11 KFM27046.1 - 0.5 10.2 7.0 1.4 8.7 0.3 3.5 3 0 0 3 3 3 0 tRNA Pseudouridine synthase II, C terminal STIMATE PF12400.8 KFM27047.1 - 8.5e-10 39.2 0.0 1.3e-09 38.7 0.0 1.3 1 0 0 1 1 1 1 STIMATE family Peptidase_M50 PF02163.22 KFM27050.1 - 0.00012 21.4 0.3 0.012 14.9 0.2 2.4 2 0 0 2 2 2 2 Peptidase family M50 DUF4042 PF13251.6 KFM27052.1 - 4.4e-25 88.5 0.3 7.3e-11 42.1 0.0 3.7 3 0 0 3 3 3 2 Domain of unknown function (DUF4042) HEAT PF02985.22 KFM27052.1 - 8.7e-06 25.6 29.2 0.015 15.5 0.2 7.4 7 1 0 7 7 7 5 HEAT repeat HEAT_EZ PF13513.6 KFM27052.1 - 0.01 16.4 0.2 0.01 16.4 0.2 8.5 6 3 3 9 9 9 3 HEAT-like repeat Ribosomal_S28e PF01200.18 KFM27054.1 - 1.1e-31 108.6 2.3 1.2e-31 108.5 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Glycos_transf_3 PF00591.21 KFM27055.1 - 9.3e-91 303.9 1.5 1.2e-90 303.5 1.5 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 KFM27055.1 - 4.9e-11 42.3 1.6 8.5e-11 41.5 1.6 1.4 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain CRAL_TRIO PF00650.20 KFM27056.1 - 2.2e-20 73.0 0.0 3e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain RWP-RK PF02042.15 KFM27056.1 - 6.9e-12 45.1 0.1 1.4e-11 44.1 0.1 1.5 1 0 0 1 1 1 1 RWP-RK domain Ribosomal_L31e PF01198.19 KFM27057.1 - 9.6e-39 131.5 2.0 1.1e-38 131.3 2.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e Ribosomal_L27e PF01777.18 KFM27058.1 - 1.3e-31 108.8 5.8 1.8e-31 108.3 5.8 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 KFM27058.1 - 0.00012 21.9 0.2 0.00024 21.0 0.2 1.4 1 0 0 1 1 1 1 KOW motif DUF2891 PF11199.8 KFM27058.1 - 0.0013 17.7 0.0 0.0015 17.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2891) Alpha-amyl_C PF09071.10 KFM27058.1 - 0.074 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Alpha-amylase, C terminal CTP_transf_1 PF01148.20 KFM27059.1 - 1.9e-54 185.2 6.4 2.1e-54 185.1 6.4 1.0 1 0 0 1 1 1 1 Cytidylyltransferase family AIRS_C PF02769.22 KFM27060.1 - 7.3e-28 97.7 0.1 1e-27 97.2 0.1 1.2 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 KFM27060.1 - 6.2e-15 55.6 0.2 9.8e-15 55.0 0.2 1.4 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain CNDH2_C PF16858.5 KFM27061.1 - 1.1e-56 192.9 0.0 2.4e-31 109.7 0.0 2.6 2 1 1 3 3 3 2 Condensin II complex subunit CAP-H2 or CNDH2, C-term CNDH2_N PF06278.11 KFM27061.1 - 1.1e-39 135.1 0.3 1.8e-39 134.4 0.3 1.4 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Cnd2 PF05786.14 KFM27061.1 - 0.00086 18.1 0.4 0.00086 18.1 0.4 3.5 4 0 0 4 4 4 2 Condensin complex subunit 2 eIF3m_C_helix PF18005.1 KFM27061.1 - 0.026 14.2 0.0 10 5.9 0.0 2.4 2 0 0 2 2 2 0 eIF3 subunit M, C-terminal helix Myosin_head PF00063.21 KFM27062.1 - 7.6e-292 969.6 0.0 2.5e-123 412.7 0.0 3.2 1 1 1 3 3 3 3 Myosin head (motor domain) DIL PF01843.19 KFM27062.1 - 7.8e-24 83.9 0.2 2.7e-23 82.2 0.2 2.0 1 0 0 1 1 1 1 DIL domain IQ PF00612.27 KFM27062.1 - 1e-13 49.8 53.7 0.00025 20.5 2.3 7.0 6 0 0 6 6 6 5 IQ calmodulin-binding motif Myosin_N PF02736.19 KFM27062.1 - 3.3e-08 33.2 2.1 5.5e-08 32.5 2.1 1.4 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Hpr_kinase_C PF07475.12 KFM27062.1 - 0.0024 17.4 0.2 18 4.8 0.0 3.3 3 0 0 3 3 3 2 HPr Serine kinase C-terminal domain AAA_16 PF13191.6 KFM27062.1 - 0.024 15.0 0.0 0.024 15.0 0.0 3.7 2 1 1 3 3 3 0 AAA ATPase domain Zeta_toxin PF06414.12 KFM27062.1 - 0.025 13.9 0.0 0.11 11.7 0.0 2.1 1 0 0 1 1 1 0 Zeta toxin Flp1_like PF16982.5 KFM27062.1 - 0.15 11.5 1.0 0.58 9.6 0.2 2.3 3 0 0 3 3 3 0 Putative Flagellin, Flp1-like, domain SNAPc_SNAP43 PF09808.9 KFM27062.1 - 0.74 9.7 5.4 12 5.8 0.5 2.4 2 0 0 2 2 2 0 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 AUX_IAA PF02309.16 KFM27063.1 - 0.04 13.8 0.1 0.051 13.4 0.1 1.1 1 0 0 1 1 1 0 AUX/IAA family SNARE_assoc PF09335.11 KFM27064.1 - 1.6e-28 99.6 7.1 1.6e-28 99.6 7.1 2.7 3 0 0 3 3 3 1 SNARE associated Golgi protein DUF2165 PF09933.9 KFM27064.1 - 0.048 13.7 0.7 0.048 13.7 0.7 2.2 2 0 0 2 2 2 0 Predicted small integral membrane protein (DUF2165) Mtc PF03820.17 KFM27064.1 - 0.19 10.8 0.0 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 Tricarboxylate carrier Metallophos PF00149.28 KFM27065.1 - 0.0004 20.9 0.0 0.00056 20.5 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pkinase PF00069.25 KFM27066.1 - 7.8e-68 228.7 0.0 9.6e-68 228.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM27066.1 - 1.8e-29 102.8 0.0 2.6e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 KFM27066.1 - 0.16 11.5 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase PNTB PF02233.16 KFM27067.1 - 1.6e-155 518.6 15.0 2.6e-155 517.9 15.0 1.3 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 KFM27067.1 - 1e-67 227.6 2.7 2.5e-67 226.3 2.7 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 KFM27067.1 - 5.8e-45 152.9 0.2 2.8e-44 150.7 0.0 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain AAA PF00004.29 KFM27067.1 - 5.4e-35 120.7 0.0 1.8e-34 119.0 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KFM27067.1 - 1.5e-07 31.3 0.0 6.8e-06 25.9 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_3 PF17862.1 KFM27067.1 - 1e-06 28.4 0.0 3e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KFM27067.1 - 1.3e-06 28.5 0.0 5.1e-06 26.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KFM27067.1 - 9e-05 22.3 0.0 0.00032 20.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KFM27067.1 - 0.00011 22.5 0.1 0.0061 16.8 0.1 2.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFM27067.1 - 0.00013 22.4 0.4 0.0015 18.9 0.4 2.7 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 KFM27067.1 - 0.00013 21.8 0.0 0.00027 20.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 KFM27067.1 - 0.00076 19.0 0.0 0.0018 17.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 KFM27067.1 - 0.00077 18.8 0.1 0.0067 15.7 0.0 2.1 1 1 1 2 2 2 1 TIP49 P-loop domain AAA_18 PF13238.6 KFM27067.1 - 0.0011 19.6 0.0 0.0022 18.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFM27067.1 - 0.0018 18.4 0.0 0.0052 17.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KFM27067.1 - 0.0025 17.2 0.1 0.0059 16.0 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KFM27067.1 - 0.0035 17.4 0.0 0.0065 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain ADH_zinc_N PF00107.26 KFM27067.1 - 0.0039 17.2 0.4 0.036 14.0 0.4 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AAA_25 PF13481.6 KFM27067.1 - 0.004 16.7 0.0 0.017 14.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KFM27067.1 - 0.0042 17.0 0.0 0.1 12.5 0.0 2.4 1 1 1 2 2 2 1 NACHT domain TPP_enzyme_M PF00205.22 KFM27067.1 - 0.0076 16.0 0.2 0.052 13.3 0.2 2.6 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain AAA_2 PF07724.14 KFM27067.1 - 0.015 15.4 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Pyr_redox_2 PF07992.14 KFM27067.1 - 0.023 14.0 0.7 0.052 12.8 0.7 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TniB PF05621.11 KFM27067.1 - 0.024 14.1 0.0 4.9 6.5 0.0 2.4 1 1 1 2 2 2 0 Bacterial TniB protein RNA_helicase PF00910.22 KFM27067.1 - 0.028 14.8 0.0 0.068 13.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.17 KFM27067.1 - 0.032 13.3 0.0 0.056 12.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 KFM27067.1 - 0.054 13.7 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KFM27067.1 - 0.06 12.7 0.0 0.38 10.0 0.0 2.2 1 1 1 2 2 2 0 KaiC Pyr_redox PF00070.27 KFM27067.1 - 0.066 13.8 0.4 0.43 11.2 0.8 2.3 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase PhoH PF02562.16 KFM27067.1 - 0.082 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein DUF815 PF05673.13 KFM27067.1 - 0.11 11.6 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_11 PF13086.6 KFM27067.1 - 0.12 12.1 0.0 0.61 9.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 KFM27067.1 - 0.13 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain 2-Hacid_dh_C PF02826.19 KFM27067.1 - 0.14 11.5 2.3 3.8 6.8 0.3 3.1 1 1 2 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TsaE PF02367.17 KFM27067.1 - 0.15 12.1 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NAD_binding_8 PF13450.6 KFM27067.1 - 0.16 12.2 1.8 0.44 10.8 1.0 2.2 2 0 0 2 2 1 0 NAD(P)-binding Rossmann-like domain Ras PF00071.22 KFM27068.1 - 1.2e-56 190.8 0.0 1.6e-56 190.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM27068.1 - 2.2e-29 102.1 0.1 3.2e-29 101.6 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase LRR_8 PF13855.6 KFM27068.1 - 1.6e-14 53.4 0.4 3.8e-05 23.4 0.0 5.1 5 0 0 5 5 5 3 Leucine rich repeat Arf PF00025.21 KFM27068.1 - 2.9e-11 43.1 0.0 4.9e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family LRR_4 PF12799.7 KFM27068.1 - 2e-08 34.4 0.3 0.32 11.5 0.0 6.5 5 2 2 7 7 7 2 Leucine Rich repeats (2 copies) F-box PF00646.33 KFM27068.1 - 9e-06 25.4 0.5 3.2e-05 23.7 0.1 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KFM27068.1 - 3e-05 23.8 0.2 8.3e-05 22.4 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box_5 PF18511.1 KFM27068.1 - 0.0029 17.1 0.0 0.0066 16.0 0.0 1.6 1 0 0 1 1 1 1 F-box GTP_EFTU PF00009.27 KFM27068.1 - 0.25 10.8 0.0 0.47 10.0 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Myb_DNA-binding PF00249.31 KFM27069.1 - 6.3e-09 35.9 0.0 0.00012 22.2 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFM27069.1 - 4.9e-06 26.7 0.0 0.00021 21.5 0.0 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Sulfate_transp PF00916.20 KFM27070.1 - 3.5e-24 85.3 22.6 5.3e-24 84.7 22.6 1.2 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 KFM27070.1 - 3e-11 43.2 0.0 9.1e-11 41.7 0.0 1.9 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 KFM27070.1 - 7e-07 28.9 0.0 1.4e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KFM27070.1 - 0.0055 17.0 0.8 0.031 14.6 0.8 2.4 1 0 0 1 1 1 1 STAS domain FKBP_C PF00254.28 KFM27071.1 - 8e-17 61.3 0.0 1.2e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase HMG_CoA_synt_C PF08540.10 KFM27072.1 - 1.1e-65 222.0 0.0 2.6e-65 220.8 0.0 1.5 2 0 0 2 2 2 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KFM27072.1 - 9.4e-55 185.2 0.0 1.5e-54 184.5 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III_C PF08541.10 KFM27072.1 - 0.007 16.5 0.2 0.039 14.1 0.1 2.1 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Thiolase_N PF00108.23 KFM27072.1 - 0.17 11.2 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Thiolase, N-terminal domain Packaging_FI PF14000.6 KFM27073.1 - 0.0083 16.6 0.3 1.1 9.8 0.0 2.6 2 1 1 3 3 3 2 DNA packaging protein FI HEAT_UF PF18817.1 KFM27073.1 - 0.1 12.8 0.1 0.45 10.8 0.0 2.0 2 0 0 2 2 2 0 Repeat of uncharacterized protein PH0542 Peptidase_C27 PF05407.12 KFM27074.1 - 0.22 11.6 4.7 0.22 11.6 1.2 2.0 1 1 0 2 2 2 0 Rubella virus endopeptidase JAB PF01398.21 KFM27075.1 - 2.4e-30 105.0 0.2 4.2e-30 104.1 0.0 1.5 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 KFM27075.1 - 1.6e-05 24.7 0.0 3.2e-05 23.7 0.0 1.5 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 KFM27075.1 - 0.0015 18.6 0.0 0.0045 17.1 0.0 1.9 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0172) eIF_4G1 PF12152.8 KFM27075.1 - 0.16 12.2 0.0 3 8.1 0.0 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4G1 LSM14 PF12701.7 KFM27076.1 - 1.3e-21 76.4 0.0 2.4e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 KFM27076.1 - 8.2e-08 33.1 1.0 0.0093 16.8 0.7 2.2 1 1 1 2 2 2 2 FDF domain DUF4126 PF13548.6 KFM27076.1 - 0.09 12.5 0.2 0.15 11.7 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4126) EccE PF11203.8 KFM27076.1 - 0.17 12.2 0.7 0.42 11.0 0.6 1.7 1 1 0 1 1 1 0 Putative type VII ESX secretion system translocon, EccE Phospholip_B PF04916.13 KFM27077.1 - 5e-138 461.0 0.0 7.5e-138 460.4 0.0 1.2 1 0 0 1 1 1 1 Phospholipase B Ribosomal_S7e PF01251.18 KFM27077.1 - 2.7e-75 252.2 0.0 3.8e-75 251.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S7e Pro_isomerase PF00160.21 KFM27078.1 - 4.4e-48 163.5 0.0 1.8e-47 161.6 0.0 2.0 3 0 0 3 3 3 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribonuclease_T2 PF00445.18 KFM27078.1 - 5.7e-36 124.5 1.9 9.7e-36 123.7 1.9 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family Rtf2 PF04641.12 KFM27078.1 - 1.9e-06 27.5 0.1 8.6e-06 25.3 0.0 1.9 2 0 0 2 2 2 1 Rtf2 RING-finger zf-NOSIP PF15906.5 KFM27078.1 - 0.0039 17.3 0.1 0.013 15.6 0.1 1.8 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein OHCU_decarbox PF09349.10 KFM27080.1 - 9.2e-23 81.4 0.0 1.5e-22 80.7 0.0 1.3 1 0 0 1 1 1 1 OHCU decarboxylase Ribonuclease_T2 PF00445.18 KFM27080.1 - 1.7e-13 51.2 0.1 3.2e-13 50.3 0.1 1.4 1 0 0 1 1 1 1 Ribonuclease T2 family WD40 PF00400.32 KFM27081.1 - 1.6e-20 73.0 16.2 7.8e-05 23.4 0.0 6.7 6 1 1 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM27081.1 - 2.4e-15 56.6 0.9 0.00011 22.4 0.1 4.4 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFM27081.1 - 0.00012 22.0 0.0 0.04 13.8 0.0 3.4 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFM27081.1 - 0.0016 17.5 0.2 0.13 11.2 0.1 2.9 1 1 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 KFM27081.1 - 0.035 13.0 4.3 2.7 6.8 0.0 2.4 2 1 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Transthyretin PF00576.21 KFM27082.1 - 4.6e-21 75.6 0.0 8.2e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 HIUase/Transthyretin family PC4 PF02229.16 KFM27083.1 - 1.4e-34 117.5 0.0 5.7e-18 64.3 0.0 3.1 3 0 0 3 3 3 3 Transcriptional Coactivator p15 (PC4) DUF3156 PF11354.8 KFM27083.1 - 0.061 13.2 0.1 1.8 8.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3156) Fapy_DNA_glyco PF01149.24 KFM27084.1 - 1.9e-30 105.9 0.1 5.2e-30 104.4 0.0 1.8 2 1 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 KFM27084.1 - 6.8e-22 77.3 0.0 1.2e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 KFM27084.1 - 0.00095 18.0 0.0 0.0018 17.1 0.0 1.4 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) Ribosomal_S13 PF00416.22 KFM27084.1 - 0.014 15.8 0.1 0.033 14.6 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein S13/S18 Holin_SPP1 PF04688.13 KFM27086.1 - 0.097 12.9 0.6 0.18 12.0 0.6 1.4 1 0 0 1 1 1 0 SPP1 phage holin Met_synt_B12 PF02965.17 KFM27087.1 - 4.1e-119 397.1 0.0 6.2e-119 396.5 0.0 1.3 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain Pterin_bind PF00809.22 KFM27087.1 - 9.5e-47 159.7 0.5 3.3e-46 158.0 0.3 2.0 2 0 0 2 2 2 1 Pterin binding enzyme B12-binding_2 PF02607.17 KFM27087.1 - 1.5e-23 83.0 0.2 9.6e-23 80.4 0.0 2.5 3 0 0 3 3 3 1 B12 binding domain B12-binding PF02310.19 KFM27087.1 - 1.4e-19 70.3 1.7 3.5e-19 69.0 0.3 2.3 2 0 0 2 2 2 1 B12 binding domain MtrH PF02007.18 KFM27087.1 - 0.0021 17.2 0.0 0.0041 16.3 0.0 1.4 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase MtrH subunit Fez1 PF06818.15 KFM27088.1 - 0.35 11.3 28.9 1.3 9.4 17.4 2.4 1 1 1 2 2 2 0 Fez1 YabA PF06156.13 KFM27088.1 - 0.4 11.3 9.4 0.22 12.2 1.7 3.2 2 1 1 3 3 3 0 Initiation control protein YabA Cnn_1N PF07989.11 KFM27088.1 - 8.8 6.6 12.1 0.91 9.7 2.0 3.2 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 DUF16 PF01519.16 KFM27089.1 - 0.057 13.9 0.7 0.095 13.2 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 Nsp1_C PF05064.13 KFM27089.1 - 0.63 9.9 4.3 0.76 9.6 2.7 1.8 1 1 0 1 1 1 0 Nsp1-like C-terminal region ABC_membrane PF00664.23 KFM27090.1 - 5.9e-115 383.6 25.5 1.1e-57 195.8 9.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFM27090.1 - 5.7e-68 227.7 0.0 8.2e-33 113.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KFM27090.1 - 3.8e-13 49.4 0.0 0.00017 21.1 0.0 4.1 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KFM27090.1 - 5.2e-08 32.5 0.3 0.0092 15.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KFM27090.1 - 1.1e-07 32.2 0.8 0.03 14.6 0.1 3.6 2 2 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KFM27090.1 - 1.6e-07 30.9 0.6 0.025 13.9 0.0 3.3 4 0 0 4 4 4 2 Zeta toxin AAA_16 PF13191.6 KFM27090.1 - 8.2e-07 29.6 6.0 0.012 16.0 0.4 2.8 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 KFM27090.1 - 6.8e-06 25.1 0.7 0.012 14.5 0.1 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_30 PF13604.6 KFM27090.1 - 1.4e-05 24.9 6.8 0.0055 16.4 0.1 3.0 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KFM27090.1 - 0.00011 22.2 0.8 0.26 11.2 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase APS_kinase PF01583.20 KFM27090.1 - 0.00011 22.1 0.3 0.26 11.2 0.1 2.5 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA PF00004.29 KFM27090.1 - 0.00024 21.5 0.1 2.3 8.7 0.0 3.6 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFM27090.1 - 0.00048 20.1 0.2 2.2 8.2 0.0 3.2 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) DUF87 PF01935.17 KFM27090.1 - 0.0009 19.4 0.8 0.53 10.3 0.1 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_15 PF13175.6 KFM27090.1 - 0.0027 17.5 0.0 0.67 9.6 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain G-alpha PF00503.20 KFM27090.1 - 0.0029 16.8 0.0 0.69 9.0 0.0 2.1 2 0 0 2 2 2 1 G-protein alpha subunit AAA_33 PF13671.6 KFM27090.1 - 0.0031 17.7 0.0 3.4 7.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KFM27090.1 - 0.0041 16.9 0.0 1.6 8.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KFM27090.1 - 0.0042 16.9 0.0 3.2 7.5 0.0 3.4 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 KFM27090.1 - 0.012 15.1 0.0 3.8 7.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 KFM27090.1 - 0.013 15.1 6.3 1.4 8.4 0.0 3.6 3 1 0 3 3 3 0 AAA domain NACHT PF05729.12 KFM27090.1 - 0.014 15.3 0.2 6.1 6.7 0.1 2.6 2 0 0 2 2 2 0 NACHT domain DUF815 PF05673.13 KFM27090.1 - 0.033 13.4 0.0 6.2 5.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_23 PF13476.6 KFM27090.1 - 0.038 14.5 0.0 12 6.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 KFM27090.1 - 0.04 13.7 0.1 8.9 6.0 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Ploopntkinase3 PF18751.1 KFM27090.1 - 0.04 13.8 1.1 8.6 6.2 0.0 3.0 3 0 0 3 3 3 0 P-loop Nucleotide Kinase3 SbcCD_C PF13558.6 KFM27090.1 - 0.051 13.8 6.7 3.5 7.9 0.4 4.1 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit Synapsin_N PF10581.9 KFM27090.1 - 0.055 13.4 0.3 6.2 6.9 0.0 2.9 3 0 0 3 3 2 0 Synapsin N-terminal AAA_18 PF13238.6 KFM27090.1 - 0.074 13.6 0.0 12 6.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KFM27090.1 - 0.099 12.7 1.6 6 7.0 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase KAP_NTPase PF07693.14 KFM27090.1 - 0.099 11.9 0.0 1.6 7.9 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain DLIC PF05783.11 KFM27090.1 - 0.29 9.9 2.4 17 4.1 0.0 2.9 3 0 0 3 3 3 0 Dynein light intermediate chain (DLIC) NTPase_1 PF03266.15 KFM27090.1 - 0.34 10.8 0.8 45 3.9 0.0 3.3 3 1 1 4 4 3 0 NTPase TruB_C PF09142.11 KFM27090.1 - 9.4 6.1 11.8 0.23 11.2 0.2 3.5 3 0 0 3 3 2 0 tRNA Pseudouridine synthase II, C terminal RabGAP-TBC PF00566.18 KFM27092.1 - 4.8e-21 75.4 0.0 1.2e-20 74.1 0.0 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain SNN_transmemb PF09049.10 KFM27092.1 - 1.9 8.5 4.8 4.1 7.4 4.8 1.5 1 0 0 1 1 1 0 Stannin transmembrane Psb28 PF03912.14 KFM27094.1 - 4.9e-41 139.3 0.0 5.4e-41 139.2 0.0 1.0 1 0 0 1 1 1 1 Psb28 protein AAA_12 PF13087.6 KFM27096.1 - 2.8e-39 134.8 0.0 4.2e-39 134.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFM27096.1 - 2.2e-22 80.1 0.1 2.9e-12 46.9 0.1 2.2 1 1 1 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 KFM27096.1 - 3.5e-10 40.0 0.1 0.0004 20.2 0.0 3.1 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 KFM27096.1 - 8.8e-05 22.9 0.0 0.00024 21.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFM27096.1 - 0.00018 21.3 0.0 0.00043 20.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFM27096.1 - 0.00067 20.1 0.1 0.0016 18.9 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain UvrD_C_2 PF13538.6 KFM27096.1 - 0.00085 19.1 0.0 0.0021 17.9 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 KFM27096.1 - 0.0064 16.8 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KFM27096.1 - 0.011 15.4 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 KFM27096.1 - 0.057 12.5 0.0 0.097 11.7 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.19 KFM27096.1 - 0.22 11.1 0.0 0.35 10.4 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF2807 PF10988.8 KFM27097.1 - 4.5e-09 36.4 7.7 6.9e-09 35.8 7.7 1.3 1 0 0 1 1 1 1 Putative auto-transporter adhesin, head GIN domain Fasciclin PF02469.22 KFM27098.1 - 8.3e-12 45.4 0.0 1.5e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 Fasciclin domain Pollen_allerg_1 PF01357.21 KFM27098.1 - 3.4e-11 43.0 0.0 1e-10 41.5 0.0 1.8 2 0 0 2 2 2 1 Pollen allergen Bap31 PF05529.12 KFM27099.1 - 2.3e-05 24.3 0.0 3.1e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Nse4_C PF08743.10 KFM27100.1 - 1.1e-18 67.3 0.0 2.8e-18 66.0 0.0 1.7 1 0 0 1 1 1 1 Nse4 C-terminal PEX11 PF05648.14 KFM27101.1 - 8.5e-36 123.5 0.0 1e-35 123.2 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Ank_2 PF12796.7 KFM27102.1 - 8.8e-23 80.7 0.3 2e-12 47.5 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFM27102.1 - 1.1e-22 79.8 5.2 1e-09 38.4 0.0 3.9 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KFM27102.1 - 1.2e-19 69.7 4.4 4e-06 27.0 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 KFM27102.1 - 1.2e-18 67.2 0.8 4.2e-11 43.1 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM27102.1 - 3e-12 45.6 0.1 0.0005 20.3 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat DUF2185 PF09951.9 KFM27102.1 - 0.009 15.8 0.2 0.015 15.1 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2185) SnoaL_2 PF12680.7 KFM27102.1 - 0.074 13.7 0.1 0.12 13.0 0.1 1.4 1 0 0 1 1 1 0 SnoaL-like domain DUF4440 PF14534.6 KFM27102.1 - 0.088 13.2 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) MFS_1 PF07690.16 KFM27104.1 - 0.00056 18.9 9.7 0.00056 18.9 9.7 2.9 1 1 3 4 4 4 3 Major Facilitator Superfamily DAO PF01266.24 KFM27105.1 - 2.8e-29 102.8 1.5 3.5e-27 95.9 1.5 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFM27105.1 - 0.00036 19.7 0.1 0.00049 19.3 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KFM27105.1 - 0.01 15.1 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ABC_tran PF00005.27 KFM27106.1 - 4.3e-23 82.3 0.0 5.8e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KFM27106.1 - 2.1e-05 24.5 0.0 0.14 12.0 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KFM27106.1 - 2.4e-05 24.8 0.4 6.1e-05 23.5 0.4 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFM27106.1 - 0.0027 18.0 0.0 0.0081 16.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KFM27106.1 - 0.0054 16.6 0.0 0.0089 15.9 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 KFM27106.1 - 0.0073 15.8 0.0 0.082 12.3 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 KFM27106.1 - 0.04 14.1 0.3 0.97 9.7 0.3 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KFM27106.1 - 0.077 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 KFM27106.1 - 0.14 11.8 0.0 5.7 6.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KFM27106.1 - 0.16 11.9 0.0 0.49 10.3 0.0 1.7 2 0 0 2 2 2 0 NACHT domain UPF0014 PF03649.13 KFM27107.1 - 5.9e-76 255.0 15.5 7e-76 254.8 15.5 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) LapA_dom PF06305.11 KFM27107.1 - 2.7 7.9 7.4 0.77 9.6 0.3 3.2 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain ABC2_membrane PF01061.24 KFM27108.1 - 9e-35 120.0 20.7 2e-34 118.8 20.7 1.6 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KFM27108.1 - 2.2e-22 80.0 0.0 3.2e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 KFM27108.1 - 6.8e-07 28.7 20.5 1.3e-06 27.8 20.5 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_16 PF13191.6 KFM27108.1 - 0.0041 17.5 0.1 0.0089 16.4 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain PDR_CDR PF06422.12 KFM27108.1 - 0.056 13.4 2.2 0.079 12.9 0.0 2.4 2 1 0 2 2 2 0 CDR ABC transporter AAA_21 PF13304.6 KFM27108.1 - 0.15 11.8 2.9 8.3 6.1 0.2 2.2 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KFM27108.1 - 0.15 11.6 1.8 1.3 8.6 0.7 2.4 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KFM27108.1 - 0.34 10.8 0.6 0.59 10.0 0.6 1.3 1 0 0 1 1 1 0 RsgA GTPase MtrG PF04210.13 KFM27108.1 - 5.3 7.0 6.4 1.8 8.5 0.4 2.3 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G BAH PF01426.18 KFM27111.1 - 2.5e-10 40.3 0.0 3.1e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 BAH domain PHD PF00628.29 KFM27111.1 - 1.2e-06 28.3 2.9 1.9e-06 27.7 2.9 1.3 1 0 0 1 1 1 1 PHD-finger PHD_4 PF16866.5 KFM27111.1 - 0.45 10.6 4.6 1.2 9.3 4.6 1.7 1 1 0 1 1 1 0 PHD-finger Pkinase PF00069.25 KFM27112.1 - 3.7e-48 164.2 0.0 5e-48 163.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM27112.1 - 5.3e-15 55.4 0.0 9.4e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFM27112.1 - 0.01 15.2 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFM27112.1 - 0.018 14.9 0.2 0.38 10.6 0.0 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family ILVD_EDD PF00920.21 KFM27113.1 - 1.5e-144 482.5 1.3 1.9e-144 482.1 1.3 1.1 1 0 0 1 1 1 1 Dehydratase family ILVD_EDD PF00920.21 KFM27114.1 - 2.1e-57 194.9 0.1 2.3e-57 194.8 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family SBP PF03110.14 KFM27115.1 - 2.6e-07 30.9 1.4 4.6e-07 30.0 1.4 1.3 1 0 0 1 1 1 1 SBP domain Helicase_C_2 PF13307.6 KFM27116.1 - 5.5e-45 153.6 0.0 1.3e-44 152.3 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 KFM27116.1 - 8.3e-45 152.5 0.0 1.2e-44 152.0 0.0 1.3 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 KFM27116.1 - 8.3e-06 25.9 0.0 0.0095 15.9 0.1 2.3 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 KFM27116.1 - 1.7e-05 24.7 0.0 0.0031 17.3 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.23 KFM27116.1 - 0.0072 15.1 0.0 0.026 13.2 0.0 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain Prok-RING_4 PF14447.6 KFM27116.1 - 0.014 15.2 1.7 0.038 13.9 1.7 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Tox-SHH PF15652.6 KFM27116.1 - 0.052 14.5 0.1 0.12 13.4 0.1 1.5 1 0 0 1 1 1 0 HNH/Endo VII superfamily toxin with a SHH signature CCM2_C PF16545.5 KFM27116.1 - 0.058 13.9 0.0 0.15 12.6 0.0 1.6 1 0 0 1 1 1 0 Cerebral cavernous malformation protein, harmonin-homology zf-RING_4 PF14570.6 KFM27116.1 - 0.082 12.7 3.3 0.21 11.4 3.3 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 KFM27116.1 - 0.094 12.7 2.8 0.22 11.5 2.8 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFM27116.1 - 0.28 11.0 3.0 0.75 9.7 3.0 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFM27116.1 - 1 9.3 6.1 0.16 11.9 1.9 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) GATA PF00320.27 KFM27117.1 - 2e-10 40.1 0.5 5e-10 38.8 0.5 1.7 1 0 0 1 1 1 1 GATA zinc finger PK PF00224.21 KFM27118.1 - 1.7e-93 313.3 0.9 2.2e-93 312.9 0.9 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KFM27118.1 - 2.2e-23 82.7 0.0 1.4e-22 80.1 0.0 2.2 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KFM27118.1 - 3.4e-06 26.4 0.9 9.7e-06 24.9 0.6 1.8 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 KFM27118.1 - 0.25 10.3 4.0 0.066 12.2 0.3 1.8 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain 2-oxoacid_dh PF00198.23 KFM27119.1 - 1.1e-77 260.7 0.1 1.4e-77 260.3 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KFM27119.1 - 1.1e-14 54.0 0.9 2.4e-14 52.9 0.9 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KFM27119.1 - 3.8e-07 29.8 2.8 0.0022 17.8 0.1 3.0 2 1 1 3 3 3 2 Biotin-lipoyl like HlyD_D23 PF16576.5 KFM27119.1 - 0.043 13.0 0.2 0.34 10.1 0.1 2.0 1 1 2 3 3 3 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion AAA PF00004.29 KFM27120.1 - 5.3e-53 179.0 0.0 4e-38 130.8 0.0 2.8 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFM27120.1 - 1.3e-11 45.2 0.0 0.00039 20.8 0.0 3.4 2 1 1 3 3 3 2 AAA ATPase domain AAA_lid_3 PF17862.1 KFM27120.1 - 3.3e-11 42.8 0.2 1e-10 41.2 0.2 1.9 1 1 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KFM27120.1 - 1.9e-09 37.9 2.1 0.00011 22.5 0.1 4.1 2 2 0 2 2 2 2 AAA domain AAA_24 PF13479.6 KFM27120.1 - 4.7e-08 33.0 0.0 0.00056 19.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KFM27120.1 - 6.9e-07 29.2 0.0 0.016 14.9 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_5 PF07728.14 KFM27120.1 - 8.9e-07 29.0 0.4 0.0024 17.9 0.2 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KFM27120.1 - 1.6e-06 28.4 0.0 3.8e-05 23.9 0.0 2.6 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 KFM27120.1 - 3.7e-06 27.5 0.0 0.015 15.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KFM27120.1 - 5.5e-06 26.1 0.5 0.12 11.9 0.0 3.0 2 1 1 3 3 3 2 AAA domain ATPase PF06745.13 KFM27120.1 - 8.8e-06 25.2 0.3 0.0029 17.0 0.0 2.6 2 1 0 2 2 2 1 KaiC AAA_7 PF12775.7 KFM27120.1 - 1.6e-05 24.5 0.0 0.0083 15.7 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region TIP49 PF06068.13 KFM27120.1 - 3e-05 23.4 0.0 0.13 11.5 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain RNA_helicase PF00910.22 KFM27120.1 - 3.4e-05 24.2 0.0 0.038 14.4 0.0 2.5 2 0 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.21 KFM27120.1 - 4.5e-05 22.9 0.2 0.005 16.3 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 KFM27120.1 - 6.5e-05 22.7 0.1 0.21 11.3 0.0 3.2 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 KFM27120.1 - 7.2e-05 22.6 0.1 0.23 11.1 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain TniB PF05621.11 KFM27120.1 - 7.2e-05 22.3 0.0 0.36 10.2 0.0 3.8 3 1 0 4 4 4 1 Bacterial TniB protein CDC48_2 PF02933.17 KFM27120.1 - 8.5e-05 22.3 1.1 0.00027 20.6 0.1 2.2 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 PhoH PF02562.16 KFM27120.1 - 0.00012 21.6 0.1 0.6 9.5 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_33 PF13671.6 KFM27120.1 - 0.00014 22.0 0.0 0.11 12.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 KFM27120.1 - 0.00021 21.3 0.0 0.77 9.8 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KFM27120.1 - 0.00039 20.7 0.0 0.21 11.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KFM27120.1 - 0.00042 20.3 3.8 4.9 7.0 0.1 3.7 4 0 0 4 4 4 0 NACHT domain AAA_14 PF13173.6 KFM27120.1 - 0.00043 20.3 0.0 0.08 13.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.17 KFM27120.1 - 0.00053 19.2 0.0 0.52 9.4 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 DUF2075 PF09848.9 KFM27120.1 - 0.0012 18.2 0.1 0.19 11.0 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KFM27120.1 - 0.0014 18.7 0.0 0.29 11.1 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit IPT PF01745.16 KFM27120.1 - 0.0017 17.8 0.2 0.013 14.9 0.1 2.2 2 0 0 2 2 2 1 Isopentenyl transferase ATPase_2 PF01637.18 KFM27120.1 - 0.002 18.1 0.1 18 5.1 0.1 3.8 2 2 1 4 4 4 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 KFM27120.1 - 0.0046 17.5 0.4 0.65 10.5 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AAA_3 PF07726.11 KFM27120.1 - 0.0077 16.1 0.0 0.33 10.8 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KFM27120.1 - 0.022 14.6 0.0 0.36 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KFM27120.1 - 0.03 13.5 0.0 0.94 8.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_29 PF13555.6 KFM27120.1 - 0.032 14.0 0.2 5.1 6.9 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_19 PF13245.6 KFM27120.1 - 0.043 14.1 0.5 2.6 8.4 0.1 2.8 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.6 KFM27120.1 - 0.055 13.2 0.0 1.5 8.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain Vps4_C PF09336.10 KFM27120.1 - 0.063 13.3 0.0 0.22 11.5 0.0 1.9 2 0 0 2 2 1 0 Vps4 C terminal oligomerisation domain AAA_23 PF13476.6 KFM27120.1 - 0.092 13.2 0.2 2.4 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 KFM27120.1 - 0.13 12.4 0.0 16 5.6 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain NB-ARC PF00931.22 KFM27120.1 - 0.64 9.1 1.6 10 5.2 0.2 2.7 2 1 0 3 3 3 0 NB-ARC domain DEAD PF00270.29 KFM27121.1 - 1.3e-42 145.5 0.0 2.2e-42 144.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM27121.1 - 5.7e-29 100.7 0.0 1.2e-28 99.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM27121.1 - 1e-05 25.6 0.0 1.5e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Pkinase PF00069.25 KFM27122.1 - 5.9e-16 58.6 0.0 5.6e-14 52.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 KFM27122.1 - 2.9e-08 32.9 0.0 4e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KFM27122.1 - 0.00064 19.1 0.0 0.004 16.5 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KFM27122.1 - 0.00065 19.7 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KFM27122.1 - 0.01 15.2 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PilX PF13681.6 KFM27122.1 - 0.016 15.6 0.0 22 5.5 0.0 3.4 3 0 0 3 3 3 0 Type IV pilus assembly protein PilX C-term Kinase-like PF14531.6 KFM27122.1 - 0.083 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Thioredoxin PF00085.20 KFM27123.1 - 1.2e-12 47.7 0.0 1.6e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 KFM27123.1 - 0.0029 17.5 0.0 0.0037 17.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KFM27123.1 - 0.021 15.1 0.0 0.033 14.5 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_2 PF13098.6 KFM27123.1 - 0.15 12.5 0.0 0.64 10.5 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin-like domain Peptidase_M9 PF01752.17 KFM27123.1 - 0.22 10.7 0.0 1.2 8.3 0.0 1.8 1 1 1 2 2 2 0 Collagenase IF-2B PF01008.17 KFM27124.1 - 9.3e-65 218.6 0.1 2.1e-63 214.2 0.0 2.0 1 1 1 2 2 2 1 Initiation factor 2 subunit family APH PF01636.23 KFM27124.1 - 6e-11 42.7 1.6 1.6e-10 41.3 1.6 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family OrfB_Zn_ribbon PF07282.11 KFM27124.1 - 0.0022 17.9 6.5 0.0099 15.8 6.5 1.9 1 1 0 1 1 1 1 Putative transposase DNA-binding domain Raffinose_syn PF05691.12 KFM27125.1 - 3.2e-150 501.4 0.0 3.9e-150 501.1 0.0 1.0 1 0 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 DUF3128 PF11326.8 KFM27126.1 - 1.1e-08 35.3 0.7 1.9e-08 34.6 0.7 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3128) UPF0203 PF05254.12 KFM27126.1 - 0.048 13.9 0.3 0.068 13.4 0.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0203) Amidohydro_3 PF07969.11 KFM27127.1 - 5.4e-33 115.2 6.6 5.7e-26 92.0 0.1 2.4 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 KFM27127.1 - 9.1e-08 31.8 0.0 2.2e-07 30.5 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase family Methyltransf_31 PF13847.6 KFM27128.1 - 6.3e-09 35.8 0.0 1.8e-08 34.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM27128.1 - 5.5e-08 33.4 0.0 1.6e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFM27128.1 - 1.8e-07 30.8 0.0 5.3e-07 29.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 KFM27128.1 - 1.8e-06 27.6 0.0 2.7e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KFM27128.1 - 6.3e-06 26.8 0.0 1.9e-05 25.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.18 KFM27128.1 - 0.00011 22.0 0.0 0.00017 21.3 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.15 KFM27128.1 - 0.00082 19.1 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 GCD14 PF08704.10 KFM27128.1 - 0.003 17.3 0.4 0.012 15.3 0.0 1.9 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_32 PF13679.6 KFM27128.1 - 0.0038 17.2 0.0 0.0059 16.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM27128.1 - 0.0063 17.2 0.0 0.1 13.4 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain PCMT PF01135.19 KFM27128.1 - 0.0069 16.2 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 KFM27128.1 - 0.014 15.2 0.0 0.046 13.5 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.10 KFM27128.1 - 0.015 14.9 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase CCDC85 PF10226.9 KFM27128.1 - 0.033 13.8 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 CCDC85 family FMN_dh PF01070.18 KFM27128.1 - 0.053 12.5 0.0 0.084 11.9 0.0 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Methyltransf_18 PF12847.7 KFM27128.1 - 0.072 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 KFM27128.1 - 0.098 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family BRK PF07533.16 KFM27128.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 BRK domain DNA_topoisoIV PF00521.20 KFM27129.1 - 1.5e-132 442.5 0.0 2.4e-132 441.9 0.0 1.3 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KFM27129.1 - 4.5e-50 169.2 0.3 1e-49 168.1 0.3 1.6 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 KFM27129.1 - 3.2e-20 72.3 0.0 8e-20 71.0 0.0 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 KFM27129.1 - 3.6e-11 43.5 0.0 9.1e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KFM27129.1 - 2.5e-08 34.0 0.0 3.6e-07 30.4 0.0 2.9 4 0 0 4 4 4 1 Toprim domain Chorismate_bind PF00425.18 KFM27130.1 - 3e-54 184.3 0.0 4.5e-54 183.7 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme TPP_enzyme_N PF02776.18 KFM27130.1 - 1.1e-29 103.3 0.1 2.5e-29 102.1 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M_2 PF16582.5 KFM27130.1 - 2.1e-18 66.8 0.0 5.6e-18 65.4 0.0 1.7 1 1 0 1 1 1 1 Middle domain of thiamine pyrophosphate MR_MLE_C PF13378.6 KFM27131.1 - 2.7e-22 79.4 0.9 2.7e-22 79.4 0.9 2.5 3 0 0 3 3 3 1 Enolase C-terminal domain-like Abhydrolase_6 PF12697.7 KFM27131.1 - 1e-18 68.7 14.4 1e-18 68.7 14.4 3.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFM27131.1 - 6.6e-14 52.2 0.1 1.7e-13 50.8 0.1 1.8 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFM27131.1 - 3.8e-10 39.4 0.1 1.5e-09 37.5 0.1 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 KFM27131.1 - 3.6e-05 23.6 0.1 7.6e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.20 KFM27131.1 - 0.00014 22.0 0.6 0.00038 20.6 0.2 1.9 2 0 0 2 2 2 1 Thioesterase domain Ndr PF03096.14 KFM27131.1 - 0.013 14.2 0.0 0.023 13.4 0.0 1.3 1 0 0 1 1 1 0 Ndr family DUF726 PF05277.12 KFM27131.1 - 0.052 12.5 0.0 0.091 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF726) BAAT_C PF08840.11 KFM27131.1 - 0.079 12.9 0.0 0.16 11.9 0.0 1.5 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Patatin PF01734.22 KFM27133.1 - 5.4e-06 26.7 1.3 0.00011 22.5 1.3 2.2 1 1 0 1 1 1 1 Patatin-like phospholipase E1-E2_ATPase PF00122.20 KFM27136.1 - 4.2e-30 104.6 8.2 6.7e-25 87.7 0.2 2.3 1 1 1 2 2 2 2 E1-E2 ATPase Hydrolase PF00702.26 KFM27136.1 - 4.2e-21 76.2 3.7 8.4e-21 75.2 3.7 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KFM27136.1 - 5.5e-08 33.1 0.0 1.1e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KFM27136.1 - 0.005 16.6 0.6 0.0077 16.0 0.6 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Metallophos_C PF14008.6 KFM27137.1 - 1.2e-11 45.3 0.2 1e-08 35.9 0.0 2.8 2 0 0 2 2 2 2 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.28 KFM27137.1 - 6.9e-07 30.0 1.1 0.00031 21.3 1.1 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFM27137.1 - 0.069 13.3 0.0 0.17 12.1 0.0 1.6 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Crystallin PF00525.18 KFM27137.1 - 0.075 13.2 1.2 2.2 8.5 0.6 2.5 2 0 0 2 2 2 0 Alpha crystallin A chain, N terminal Metallophos PF00149.28 KFM27138.1 - 1.1e-20 75.0 1.3 1.6e-20 74.5 0.5 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 KFM27138.1 - 1.4e-18 67.2 5.6 2.3e-18 66.5 4.1 2.1 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 KFM27138.1 - 3.3e-14 53.5 0.4 3e-12 47.2 0.4 3.1 1 1 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C fn3 PF00041.21 KFM27138.1 - 0.016 15.6 0.8 1.5 9.2 0.1 2.9 3 0 0 3 3 3 0 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFM27139.1 - 2e-18 66.8 4.5 9.3e-18 64.6 3.5 2.3 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 KFM27139.1 - 6.2e-14 53.0 0.5 1.2e-12 48.8 0.5 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 KFM27139.1 - 2.8e-13 50.5 0.3 1.8e-11 44.7 0.3 2.8 1 1 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PAC2 PF09754.9 KFM27140.1 - 2.5e-20 73.4 0.0 3.6e-20 72.9 0.0 1.3 1 1 0 1 1 1 1 PAC2 family PI3K_P85_iSH2 PF16454.5 KFM27141.1 - 0.032 13.9 0.4 0.077 12.6 0.4 1.6 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain SYCE1 PF15233.6 KFM27141.1 - 0.51 10.4 15.5 0.031 14.3 7.8 2.3 1 1 2 3 3 3 0 Synaptonemal complex central element protein 1 CENP-F_leu_zip PF10473.9 KFM27141.1 - 4.5 7.3 23.3 5.6 7.0 0.6 4.1 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 KFM27141.1 - 8.6 5.7 22.4 1.2 8.5 11.2 3.0 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding TFIIA PF03153.13 KFM27141.1 - 9.6 6.1 7.2 13 5.6 7.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GAS PF13851.6 KFM27143.1 - 0.0023 17.3 9.3 0.027 13.8 1.1 2.9 1 1 2 3 3 3 3 Growth-arrest specific micro-tubule binding Filament PF00038.21 KFM27143.1 - 0.17 11.4 11.3 1.1 8.7 3.3 2.2 1 1 1 2 2 2 0 Intermediate filament protein Acetyltransf_1 PF00583.25 KFM27145.1 - 1.3e-10 41.5 0.0 1.7e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFM27145.1 - 3.4e-09 36.7 0.0 5.7e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFM27145.1 - 2.8e-08 34.1 0.0 4e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFM27145.1 - 1.7e-05 24.7 0.0 2.8e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KFM27145.1 - 0.19 11.8 0.0 0.32 11.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Helicase_C PF00271.31 KFM27146.1 - 2.3e-26 92.3 0.0 4.1e-26 91.5 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFM27146.1 - 2.8e-11 43.5 0.1 3.1e-09 36.8 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase 6PGD PF00393.19 KFM27147.1 - 4.1e-110 367.7 0.0 2.5e-109 365.1 0.0 1.9 1 1 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KFM27147.1 - 1.7e-48 164.7 0.0 3.6e-48 163.7 0.1 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KFM27147.1 - 0.014 15.3 0.1 0.023 14.6 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KFM27147.1 - 0.018 15.6 0.1 0.045 14.3 0.1 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KFM27147.1 - 0.019 14.3 0.1 0.036 13.4 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KFM27147.1 - 0.085 12.4 0.2 2.8 7.5 0.2 2.4 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ARID PF01388.21 KFM27148.1 - 1e-12 48.5 0.0 1.6e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain LINES_C PF14695.6 KFM27148.1 - 0.0084 15.5 0.2 0.016 14.7 0.2 1.3 1 0 0 1 1 1 1 Lines C-terminus Ank_2 PF12796.7 KFM27149.1 - 7.2e-32 109.8 0.0 1.1e-11 45.2 0.1 3.7 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFM27149.1 - 8.9e-29 99.2 0.5 7.1e-11 42.1 0.0 5.1 1 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KFM27149.1 - 1.3e-28 98.2 6.2 1e-07 32.1 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 KFM27149.1 - 1.5e-27 92.6 0.0 2.2e-05 24.5 0.0 6.4 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.6 KFM27149.1 - 1.4e-26 92.5 0.3 2.1e-09 37.7 0.0 4.4 2 2 3 5 5 5 3 Ankyrin repeats (many copies) Dynamin_N PF00350.23 KFM27150.1 - 3.7e-27 95.4 0.0 6.6e-27 94.6 0.0 1.4 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KFM27150.1 - 0.00013 22.0 0.0 0.00029 20.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase LD_cluster2 PF18163.1 KFM27150.1 - 0.019 14.5 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 SLOG cluster2 AAA_16 PF13191.6 KFM27150.1 - 0.29 11.5 5.4 0.65 10.4 0.0 3.3 3 2 0 3 3 3 0 AAA ATPase domain eIF-1a PF01176.19 KFM27151.1 - 9.4e-07 28.6 0.0 1.8e-06 27.6 0.0 1.5 1 1 1 2 2 2 1 Translation initiation factor 1A / IF-1 FMN_dh PF01070.18 KFM27152.1 - 1.2e-111 373.1 0.1 2.2e-111 372.3 0.1 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase PsbP PF01789.16 KFM27152.1 - 5.1e-16 59.2 0.0 8.2e-15 55.3 0.0 2.1 1 1 0 1 1 1 1 PsbP DMRL_synthase PF00885.19 KFM27154.1 - 4.5e-53 178.9 1.1 5.2e-53 178.7 1.1 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase YccF PF03733.13 KFM27155.1 - 1.4e-21 76.9 24.2 3e-15 56.6 5.8 2.1 2 0 0 2 2 2 2 Inner membrane component domain Senescence_reg PF04520.13 KFM27156.1 - 0.034 15.0 1.4 0.14 13.0 1.4 2.2 1 1 0 1 1 1 0 Senescence regulator DUF1118 PF06549.12 KFM27157.1 - 0.05 13.9 1.4 0.091 13.1 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1118) 60KD_IMP PF02096.20 KFM27158.1 - 1.7e-19 70.3 0.1 2.3e-19 69.9 0.1 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein Ribosomal_L14 PF00238.19 KFM27160.1 - 5.1e-34 117.0 0.0 6.1e-34 116.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Peptidase_M41 PF01434.18 KFM27161.1 - 3.2e-63 213.0 0.1 6.9e-63 212.0 0.1 1.6 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KFM27161.1 - 6e-24 84.9 0.0 1.4e-23 83.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sec20 PF03908.13 KFM27161.1 - 6.8e-15 54.8 0.0 1.4e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Sec20 AAA_lid_3 PF17862.1 KFM27161.1 - 5.5e-12 45.3 0.1 1.6e-11 43.8 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 KFM27161.1 - 1.7e-06 28.3 0.0 5e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 FtsH Extracellular V-SNARE_C PF12352.8 KFM27161.1 - 0.0026 18.0 1.2 0.0087 16.3 0.5 2.2 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus RPA_C PF08784.11 KFM27162.1 - 1.4e-07 32.1 0.5 2.7e-07 31.2 0.2 1.7 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 KFM27162.1 - 3.1e-05 23.8 0.0 6.6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 KFM27162.1 - 0.0056 16.5 0.0 0.0089 15.8 0.0 1.3 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 CDC24_OB3 PF17244.2 KFM27162.1 - 0.047 13.4 0.1 0.069 12.9 0.1 1.2 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 3 WBS_methylT PF12589.8 KFM27163.1 - 3.6e-15 56.5 4.5 6.3e-15 55.7 4.5 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 KFM27163.1 - 1.3e-12 48.2 0.0 2.1e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM27163.1 - 4.1e-10 40.2 0.0 9e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM27163.1 - 5.1e-07 29.7 0.0 1.4e-06 28.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM27163.1 - 6.4e-06 26.8 0.0 1.8e-05 25.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM27163.1 - 0.0044 16.8 0.0 0.0064 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Snf7 PF03357.21 KFM27164.1 - 2e-34 118.7 22.3 2.9e-34 118.2 22.3 1.3 1 1 0 1 1 1 1 Snf7 Sas10 PF09368.10 KFM27164.1 - 0.0067 16.9 1.7 0.011 16.2 1.7 1.4 1 0 0 1 1 1 1 Sas10 C-terminal domain SYF2 PF08231.12 KFM27164.1 - 0.059 13.8 4.1 0.085 13.3 4.1 1.2 1 0 0 1 1 1 0 SYF2 splicing factor AvrPphF-ORF-2 PF09143.10 KFM27164.1 - 0.075 13.0 0.4 0.14 12.1 0.4 1.7 1 1 0 1 1 1 0 AvrPphF-ORF-2 Erf4 PF10256.9 KFM27164.1 - 0.077 13.1 0.1 0.15 12.2 0.1 1.3 1 1 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family DUF4239 PF14023.6 KFM27164.1 - 0.97 9.1 3.4 1.7 8.4 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) V_ATPase_I PF01496.19 KFM27164.1 - 1.2 7.0 6.0 1.5 6.7 6.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_23 PF13476.6 KFM27164.1 - 2.6 8.5 10.7 4 7.9 10.7 1.4 1 1 0 1 1 1 0 AAA domain RabGAP-TBC PF00566.18 KFM27166.1 - 7.3e-50 169.6 0.0 1e-49 169.1 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GCN5L1 PF06320.13 KFM27166.1 - 0.13 12.4 5.4 0.14 12.3 2.9 2.3 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) ExsD PF16806.5 KFM27166.1 - 0.21 11.5 2.0 0.43 10.4 2.0 1.4 1 0 0 1 1 1 0 Antiactivator protein ExsD Spc7 PF08317.11 KFM27166.1 - 2.2 7.1 8.1 0.96 8.3 1.2 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein BAR PF03114.18 KFM27167.1 - 1.1e-05 25.2 0.4 4.2e-05 23.3 0.4 1.8 1 1 0 1 1 1 1 BAR domain P2_Phage_GpR PF06891.11 KFM27167.1 - 0.052 13.6 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 P2 phage tail completion protein R (GpR) APG6_N PF17675.1 KFM27167.1 - 0.086 13.4 1.3 0.16 12.5 1.3 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region Zw10 PF06248.13 KFM27167.1 - 0.11 11.0 0.2 0.15 10.6 0.2 1.2 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 FAM76 PF16046.5 KFM27167.1 - 0.26 10.6 0.2 0.32 10.3 0.2 1.1 1 0 0 1 1 1 0 FAM76 protein COG2 PF06148.11 KFM27167.1 - 0.5 10.5 5.9 0.39 10.8 1.5 2.4 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Peptidase_M16_C PF05193.21 KFM27169.1 - 2.5e-37 128.7 0.0 6.6e-21 75.1 0.0 2.9 2 1 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KFM27169.1 - 3.7e-22 78.9 0.1 7.7e-22 77.9 0.1 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) GBP_repeat PF02526.14 KFM27169.1 - 0.11 12.2 0.5 0.23 11.2 0.5 1.5 1 0 0 1 1 1 0 Glycophorin-binding protein ATP-synt_Z PF16594.5 KFM27169.1 - 0.12 11.8 0.1 0.29 10.7 0.1 1.5 1 0 0 1 1 1 0 Putative AtpZ or ATP-synthase-associated CPSase_L_D2 PF02786.17 KFM27170.1 - 6.2e-81 270.9 0.0 1.3e-80 269.9 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KFM27170.1 - 5.7e-46 155.6 0.1 1.2e-45 154.5 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KFM27170.1 - 2.5e-39 133.7 0.0 5.4e-39 132.6 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp PF02222.22 KFM27170.1 - 7.1e-07 29.0 0.0 2.4e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KFM27170.1 - 0.00022 20.8 0.0 0.00052 19.6 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus RimK PF08443.11 KFM27170.1 - 0.0031 17.1 0.0 0.01 15.5 0.0 1.8 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATPgrasp_Ter PF15632.6 KFM27170.1 - 0.0099 15.6 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_5 PF13549.6 KFM27170.1 - 0.013 15.0 0.1 0.044 13.2 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain ATP-grasp_3 PF02655.14 KFM27170.1 - 0.037 14.1 0.0 0.096 12.7 0.0 1.7 1 1 0 1 1 1 0 ATP-grasp domain Peripla_BP_3 PF13377.6 KFM27170.1 - 0.04 14.3 0.2 0.29 11.4 0.1 2.2 2 0 0 2 2 2 0 Periplasmic binding protein-like domain Pkinase PF00069.25 KFM27172.1 - 1e-59 202.1 0.0 1.3e-59 201.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM27172.1 - 4.7e-23 81.8 0.0 6.5e-23 81.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM27172.1 - 0.026 13.8 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 KFM27172.1 - 0.051 12.9 0.1 0.16 11.3 0.1 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L10 PF00466.20 KFM27173.1 - 2.7e-05 24.2 0.0 6.1e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_L37ae PF01780.19 KFM27174.1 - 5.6e-41 138.5 6.9 6.3e-41 138.4 6.9 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family NOB1_Zn_bind PF08772.11 KFM27174.1 - 0.009 16.2 3.7 0.017 15.3 1.1 2.2 1 1 1 2 2 2 1 Nin one binding (NOB1) Zn-ribbon like Zn_Tnp_IS1595 PF12760.7 KFM27174.1 - 0.015 15.2 2.7 0.025 14.6 2.7 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-RING_13 PF17977.1 KFM27174.1 - 0.016 15.3 0.4 0.022 14.9 0.4 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-FPG_IleRS PF06827.14 KFM27174.1 - 0.028 14.3 0.1 0.076 12.9 0.1 1.8 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS C1_1 PF00130.22 KFM27174.1 - 0.034 14.0 3.0 0.047 13.6 3.0 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) MRNIP PF15749.5 KFM27174.1 - 0.055 14.2 5.4 0.28 11.9 2.4 2.1 1 1 1 2 2 2 0 MRN-interacting protein Glyco_transf_4 PF13439.6 KFM27175.1 - 4.9e-17 62.4 0.9 9.2e-17 61.6 0.9 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KFM27175.1 - 1.2e-12 48.6 6.3 1.2e-12 48.6 6.3 2.7 1 1 1 2 2 2 1 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.20 KFM27175.1 - 3e-12 46.4 0.0 4.6e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 KFM27175.1 - 0.019 15.0 0.0 0.034 14.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like DDA1 PF10172.9 KFM27176.1 - 4.9e-13 49.1 0.0 1.3e-11 44.6 0.0 2.2 2 0 0 2 2 2 1 Det1 complexing ubiquitin ligase SAP PF02037.27 KFM27176.1 - 7e-07 28.8 0.1 1.2e-06 28.1 0.1 1.4 1 0 0 1 1 1 1 SAP domain Rho_N PF07498.12 KFM27176.1 - 0.076 13.0 0.1 0.16 12.0 0.1 1.6 1 1 0 1 1 1 0 Rho termination factor, N-terminal domain DUF1265 PF06887.14 KFM27177.1 - 0.21 11.6 0.5 0.47 10.5 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1265) HSP70 PF00012.20 KFM27178.1 - 4.6e-24 84.6 0.0 3.1e-13 48.8 0.0 2.2 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 KFM27178.1 - 0.035 12.9 0.0 0.072 11.9 0.0 1.5 2 0 0 2 2 2 0 MreB/Mbl protein Ntox3 PF15536.6 KFM27178.1 - 0.092 12.8 0.5 2.5 8.1 0.1 2.2 1 1 1 2 2 2 0 Bacterial toxin 3 AhpC-TSA PF00578.21 KFM27179.1 - 2.4e-25 88.9 0.0 3.2e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KFM27179.1 - 2.8e-20 72.5 0.0 4.1e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 KFM27179.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme MCM PF00493.23 KFM27180.1 - 2e-95 318.1 0.1 4.1e-95 317.1 0.0 1.5 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KFM27180.1 - 6.9e-31 106.7 1.0 1.2e-30 105.9 1.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KFM27180.1 - 1.4e-23 83.1 0.1 3.7e-23 81.8 0.1 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KFM27180.1 - 1.4e-10 41.6 0.0 3.2e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KFM27180.1 - 5.5e-08 32.4 0.0 2.2e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KFM27180.1 - 0.00033 20.7 0.0 0.00073 19.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KFM27180.1 - 0.0083 16.0 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KFM27180.1 - 0.076 12.7 0.0 0.17 11.6 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain DS PF01916.17 KFM27181.1 - 4.2e-125 416.8 0.0 4.8e-125 416.6 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase DUF846 PF05832.12 KFM27182.1 - 6.4e-50 168.8 6.8 9.1e-50 168.3 6.8 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Pox_MCEL PF03291.16 KFM27182.1 - 9.2e-13 48.0 0.2 3.9e-12 45.9 0.2 1.9 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_12 PF08242.12 KFM27182.1 - 0.00014 22.5 0.0 0.00023 21.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM27182.1 - 0.0035 18.0 0.0 0.0087 16.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFM27182.1 - 0.0054 17.4 0.0 0.0093 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF3023 PF11224.8 KFM27182.1 - 0.026 14.3 0.0 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3023) Methyltransf_23 PF13489.6 KFM27182.1 - 0.035 13.9 0.0 0.057 13.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KFM27182.1 - 0.18 11.6 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain GARS_A PF01071.19 KFM27183.1 - 1.1e-85 286.3 0.0 6.7e-75 251.1 0.0 2.1 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 KFM27183.1 - 1.2e-32 112.6 0.1 2.2e-32 111.7 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 KFM27183.1 - 2.3e-30 104.7 0.8 5.5e-29 100.3 0.1 2.5 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain ATP-grasp PF02222.22 KFM27183.1 - 1.1e-05 25.1 0.0 2.1e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 KFM27183.1 - 0.00042 19.9 0.4 0.00076 19.0 0.4 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.11 KFM27183.1 - 0.00088 18.9 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.6 KFM27183.1 - 0.0015 18.1 0.0 0.0028 17.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KFM27183.1 - 0.017 14.7 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus ATP-grasp_2 PF08442.10 KFM27183.1 - 0.022 14.3 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_3 PF02655.14 KFM27183.1 - 0.067 13.2 0.0 0.19 11.8 0.0 1.8 2 0 0 2 2 2 0 ATP-grasp domain TPR_2 PF07719.17 KFM27185.1 - 4.3e-09 35.8 5.0 0.00068 19.6 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFM27185.1 - 2e-05 24.2 0.8 0.68 9.7 0.0 3.3 3 0 0 3 3 3 2 TPR repeat TPR_8 PF13181.6 KFM27185.1 - 0.00016 21.6 0.2 0.36 11.1 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFM27185.1 - 0.00018 21.2 1.9 0.06 13.2 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFM27185.1 - 0.029 14.9 2.2 0.029 14.9 2.2 3.4 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFM27185.1 - 0.049 13.7 6.4 6.8 7.0 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFM27185.1 - 0.085 13.7 0.8 0.085 13.7 0.8 5.8 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 KFM27185.1 - 0.11 12.7 16.6 0.49 10.6 7.3 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFM27185.1 - 2.7 8.8 0.0 2.7 8.8 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFM27185.1 - 3.2 8.5 32.5 1.1 10.0 8.3 4.4 3 2 1 4 4 4 0 Tetratricopeptide repeat RRM_1 PF00076.22 KFM27186.1 - 5e-25 87.1 0.0 2.5e-12 46.4 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cu2_monoox_C PF03712.15 KFM27186.1 - 4.3e-21 75.0 0.0 1.2e-20 73.6 0.0 1.6 2 0 0 2 2 2 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 KFM27186.1 - 5.1e-21 75.3 0.1 1.1e-20 74.2 0.1 1.4 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain NHL PF01436.21 KFM27186.1 - 3e-11 42.8 1.7 0.00024 21.0 0.2 4.0 3 0 0 3 3 3 3 NHL repeat zf-CHY PF05495.12 KFM27186.1 - 1.6e-09 38.1 11.6 1.6e-09 38.1 11.6 2.9 3 0 0 3 3 3 1 CHY zinc finger RRM_7 PF16367.5 KFM27186.1 - 0.00034 20.7 0.0 0.0012 18.9 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif RecO_N PF11967.8 KFM27187.1 - 0.096 12.7 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 Recombination protein O N terminal NadA PF02445.16 KFM27188.1 - 2.1e-32 112.5 0.6 1.6e-30 106.3 0.2 2.1 2 0 0 2 2 2 2 Quinolinate synthetase A protein SufE PF02657.15 KFM27188.1 - 2.3e-23 82.4 0.0 4.5e-23 81.4 0.0 1.5 1 0 0 1 1 1 1 Fe-S metabolism associated domain ALAD PF00490.21 KFM27188.1 - 0.05 12.8 1.8 0.096 11.8 0.7 1.8 2 0 0 2 2 2 0 Delta-aminolevulinic acid dehydratase DUF5593 PF18007.1 KFM27188.1 - 0.095 13.4 0.3 0.41 11.4 0.2 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF5593) Ribosomal_S5 PF00333.20 KFM27189.1 - 8.5e-31 105.7 2.3 1.3e-30 105.1 2.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 KFM27189.1 - 9.4e-25 85.9 0.2 1.6e-24 85.1 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain polyprenyl_synt PF00348.17 KFM27190.1 - 9.7e-65 218.2 0.0 1.1e-64 217.9 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase BPL_N PF09825.9 KFM27191.1 - 1.9e-71 241.1 0.0 2.4e-71 240.8 0.0 1.0 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal SNO PF01174.19 KFM27191.1 - 0.0049 16.7 0.0 0.009 15.9 0.0 1.3 1 0 0 1 1 1 1 SNO glutamine amidotransferase family PhzC-PhzF PF02567.16 KFM27192.1 - 1e-56 192.5 0.0 1.2e-56 192.3 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Peptidase_M24 PF00557.24 KFM27193.1 - 1.2e-54 185.2 0.3 1.4e-54 185.0 0.3 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 DnaJ PF00226.31 KFM27194.1 - 5.6e-17 61.6 0.0 8.2e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Antimicrobial_1 PF08018.11 KFM27195.1 - 4.6 7.5 4.7 0.98 9.6 0.3 2.0 2 0 0 2 2 2 0 Frog antimicrobial peptide RIB43A PF05914.12 KFM27196.1 - 0.015 14.1 18.7 0.0069 15.2 15.8 1.6 1 1 1 2 2 2 0 RIB43A E3_UFM1_ligase PF09743.9 KFM27198.1 - 1e-62 212.3 0.0 1.3e-62 211.9 0.0 1.1 1 0 0 1 1 1 1 E3 UFM1-protein ligase 1 AAA_assoc_C PF09821.9 KFM27198.1 - 0.016 15.8 0.7 0.38 11.3 0.0 3.2 3 0 0 3 3 3 0 C-terminal AAA-associated domain HTH_9 PF08221.11 KFM27198.1 - 0.18 11.9 0.0 0.39 10.9 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Nic96 PF04097.14 KFM27199.1 - 1.1e-51 176.1 0.0 6.7e-49 166.9 0.0 2.9 1 1 0 1 1 1 1 Nup93/Nic96 PTPA PF03095.15 KFM27199.1 - 0.096 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Phosphotyrosyl phosphate activator (PTPA) protein MFS_3 PF05977.13 KFM27201.1 - 1.8e-08 33.2 14.4 1.8e-08 33.2 14.4 3.0 2 1 0 2 2 2 1 Transmembrane secretion effector MFS_1 PF07690.16 KFM27201.1 - 4.8e-05 22.5 41.7 0.00014 20.9 17.8 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF4407 PF14362.6 KFM27203.1 - 0.0021 17.4 0.1 0.0026 17.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) NPV_P10 PF05531.12 KFM27203.1 - 0.047 14.2 1.1 15 6.2 0.2 2.8 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein YabA PF06156.13 KFM27203.1 - 0.064 13.9 0.0 7 7.3 0.0 2.2 2 0 0 2 2 2 0 Initiation control protein YabA DASH_Duo1 PF08651.10 KFM27203.1 - 0.064 13.0 0.0 8.2 6.3 0.0 2.3 2 0 0 2 2 2 0 DASH complex subunit Duo1 TolA_bind_tri PF16331.5 KFM27203.1 - 0.18 11.9 2.3 0.52 10.4 0.0 2.5 3 0 0 3 3 3 0 TolA binding protein trimerisation DUF4140 PF13600.6 KFM27203.1 - 0.42 11.1 6.0 3.9 8.0 0.9 2.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) TMF_TATA_bd PF12325.8 KFM27203.1 - 0.77 10.0 3.5 2.5 8.3 0.3 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding SlyX PF04102.12 KFM27203.1 - 2.1 9.0 7.5 15 6.3 1.0 2.6 2 0 0 2 2 2 0 SlyX TIMELESS PF04821.14 KFM27204.1 - 5.7e-30 104.5 0.0 8.7e-30 103.9 0.0 1.3 1 0 0 1 1 1 1 Timeless protein TIMELESS_C PF05029.13 KFM27204.1 - 3.5e-07 29.8 0.8 0.0013 17.9 0.0 3.2 4 0 0 4 4 4 2 Timeless protein C terminal region Myb_DNA-binding PF00249.31 KFM27204.1 - 0.00027 21.1 0.0 0.0048 17.0 0.0 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain ssDBP PF17878.1 KFM27204.1 - 0.099 12.9 0.1 0.22 11.8 0.1 1.5 1 0 0 1 1 1 0 Single-stranded DNA-binding protein Cofilin_ADF PF00241.20 KFM27205.1 - 2.7e-30 104.6 0.0 3.6e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Phage_XkdX PF09693.10 KFM27205.1 - 0.018 15.1 0.4 6.7 6.8 0.0 3.7 3 1 1 4 4 4 0 Phage uncharacterised protein (Phage_XkdX) TetR_C_7 PF14246.6 KFM27205.1 - 0.026 14.5 0.3 0.058 13.4 0.1 1.7 2 0 0 2 2 2 0 AefR-like transcriptional repressor, C-terminal domain Pro_isomerase PF00160.21 KFM27206.1 - 3.8e-32 111.8 0.0 5.2e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PAN_4 PF14295.6 KFM27206.1 - 2.2e-08 33.8 7.8 4e-08 33.0 7.8 1.4 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 KFM27206.1 - 0.0022 17.9 2.1 0.0037 17.2 2.1 1.4 1 0 0 1 1 1 1 PAN domain MANEC PF07502.14 KFM27206.1 - 0.033 14.4 3.7 0.063 13.6 3.7 1.3 1 0 0 1 1 1 0 MANEC domain ATP-synt_G PF04718.15 KFM27207.1 - 4.4e-13 49.9 0.1 6.4e-13 49.4 0.1 1.4 1 1 0 1 1 1 1 Mitochondrial ATP synthase g subunit UPF0240 PF06784.11 KFM27207.1 - 0.0034 17.5 0.3 0.0071 16.4 0.3 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0240) DUF2465 PF10239.9 KFM27208.1 - 2.4e-19 69.7 0.0 3.7e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2465) RL10P_insert PF17777.1 KFM27209.1 - 1.1e-15 57.4 0.0 2.1e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 KFM27209.1 - 2.1e-14 53.4 0.0 3.5e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 DUF4685 PF15737.5 KFM27211.1 - 0.1 13.1 0.3 0.29 11.6 0.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4685) DUF760 PF05542.11 KFM27212.1 - 9.1e-19 67.6 0.0 1.4e-13 51.0 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF760) Ank_2 PF12796.7 KFM27214.1 - 6.1e-41 138.9 2.9 4e-12 46.5 0.4 3.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM27214.1 - 1.3e-25 89.4 0.5 2.8e-06 27.8 0.0 4.4 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM27214.1 - 6.4e-25 84.5 1.3 0.0051 17.2 0.0 6.5 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 KFM27214.1 - 1.8e-22 79.1 7.4 3.2e-06 27.3 0.2 5.5 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KFM27214.1 - 4.5e-19 68.0 13.0 0.00026 21.3 0.1 6.2 7 0 0 7 7 7 5 Ankyrin repeat TPR_1 PF00515.28 KFM27214.1 - 2.7e-07 30.1 2.8 0.0045 16.7 0.2 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFM27214.1 - 8.3e-06 25.5 10.2 0.008 16.2 0.6 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFM27214.1 - 0.0058 17.3 6.5 0.0058 17.3 6.5 6.1 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFM27214.1 - 0.032 14.7 7.3 0.24 11.9 0.0 3.8 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFM27214.1 - 0.33 11.3 1.3 52 4.4 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DnaJ PF00226.31 KFM27215.1 - 8.2e-07 29.1 0.1 1.5e-06 28.2 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain HSCB_C PF07743.13 KFM27215.1 - 0.14 12.7 1.7 1.4 9.5 0.2 2.3 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain HA PF03457.14 KFM27216.1 - 2.5e-06 27.7 0.0 0.00027 21.2 0.0 2.5 1 1 0 1 1 1 1 Helicase associated domain NDUFA12 PF05071.16 KFM27217.1 - 3.3e-20 72.7 5.2 4.5e-20 72.3 5.2 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Pkinase PF00069.25 KFM27219.1 - 5.4e-59 199.7 0.0 3.6e-36 124.9 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFM27219.1 - 9.7e-28 97.1 0.0 4.4e-19 68.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase DUF789 PF05623.12 KFM27219.1 - 5.8e-15 55.7 0.0 8.5e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF789) Kinase-like PF14531.6 KFM27219.1 - 7.7e-09 35.3 0.0 6e-06 25.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KFM27219.1 - 1.9e-08 34.5 0.5 3e-05 24.1 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KFM27219.1 - 0.0015 18.0 0.8 0.0052 16.2 0.0 2.1 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFM27219.1 - 0.019 14.5 0.0 0.042 13.4 0.0 1.5 2 0 0 2 2 2 0 RIO1 family Pro_isomerase PF00160.21 KFM27220.1 - 2.4e-47 161.1 0.1 2.9e-47 160.9 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Chloroa_b-bind PF00504.21 KFM27222.1 - 1.2e-44 152.7 0.0 1.5e-44 152.4 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Pyr_redox_2 PF07992.14 KFM27223.1 - 4.1e-59 200.2 1.5 5.5e-59 199.8 1.5 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KFM27223.1 - 1e-30 106.2 0.4 1.8e-30 105.4 0.4 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KFM27223.1 - 2.9e-21 75.8 0.2 2.1e-19 69.9 0.0 3.4 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFM27223.1 - 3e-09 36.5 0.1 2.4e-08 33.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFM27223.1 - 5.8e-05 22.4 0.1 0.028 13.5 0.0 2.3 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KFM27223.1 - 0.0058 15.9 3.6 0.017 14.3 0.4 2.6 2 1 1 3 3 3 1 Thi4 family 2-Hacid_dh_C PF02826.19 KFM27223.1 - 0.036 13.4 0.0 0.13 11.6 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 KFM27223.1 - 0.14 11.4 0.7 0.35 10.1 0.1 1.9 2 0 0 2 2 2 0 FAD binding domain CCDC50_N PF15295.6 KFM27225.1 - 0.0015 18.7 3.6 0.0015 18.7 3.6 1.8 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 50 N-terminus Apolipoprotein PF01442.18 KFM27226.1 - 0.00012 22.0 33.8 0.02 14.8 13.5 3.1 2 1 0 2 2 2 2 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 KFM27226.1 - 0.00063 19.9 6.9 0.0053 16.9 0.6 3.5 3 1 0 4 4 4 1 Apolipophorin-III precursor (apoLp-III) DUF883 PF05957.13 KFM27226.1 - 0.31 11.7 46.0 2.6 8.7 8.5 5.9 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF883) Mitofilin PF09731.9 KFM27226.1 - 1.5 7.5 31.0 2.5 6.9 17.7 2.2 2 0 0 2 2 2 0 Mitochondrial inner membrane protein GTP_cyclohydroI PF01227.22 KFM27227.1 - 1.4e-45 155.0 0.0 1.2e-34 119.4 0.0 2.1 2 0 0 2 2 2 2 GTP cyclohydrolase I RMI2 PF16100.5 KFM27228.1 - 2.8e-14 53.1 0.0 3e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 Per1 PF04080.13 KFM27229.1 - 9.5e-23 81.3 6.4 1e-22 81.1 6.4 1.0 1 0 0 1 1 1 1 Per1-like family DUF883 PF05957.13 KFM27230.1 - 3e-05 24.5 17.7 0.097 13.3 3.8 3.2 1 1 2 3 3 3 3 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 KFM27230.1 - 6.4e-05 23.4 23.6 2.2 8.8 4.8 3.7 1 1 1 2 2 2 1 YtxH-like protein Apolipoprotein PF01442.18 KFM27230.1 - 0.0035 17.2 9.4 0.07 13.0 9.4 2.1 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 KFM27230.1 - 0.021 14.9 5.7 0.18 11.9 3.4 2.2 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) CsbD PF05532.12 KFM27230.1 - 0.069 13.1 30.2 0.23 11.4 6.6 5.2 2 1 2 4 4 4 0 CsbD-like DivIVA PF05103.13 KFM27230.1 - 0.16 12.0 14.8 0.3 11.2 0.8 3.0 2 1 1 3 3 3 0 DivIVA protein Borrelia_P83 PF05262.11 KFM27230.1 - 0.2 10.1 14.2 0.28 9.6 14.2 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein RRF PF01765.19 KFM27230.1 - 0.22 11.5 14.7 0.088 12.8 2.0 2.6 1 1 2 3 3 3 0 Ribosome recycling factor ZYG-11_interact PF05884.12 KFM27230.1 - 0.23 10.9 1.9 0.49 9.8 1.0 1.7 1 1 1 2 2 2 0 Interactor of ZYG-11 ATP-synt_B PF00430.18 KFM27230.1 - 0.82 9.8 22.6 1.5 8.9 9.6 2.9 1 1 2 3 3 3 0 ATP synthase B/B' CF(0) WXG100 PF06013.12 KFM27230.1 - 0.97 9.7 9.9 9.8 6.5 0.4 3.1 1 1 3 4 4 4 0 Proteins of 100 residues with WXG DUF2884 PF11101.8 KFM27230.1 - 1.1 8.8 6.3 2.6 7.5 0.8 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2884) Tape_meas_lam_C PF09718.10 KFM27230.1 - 1.1 9.4 8.2 7.5 6.8 0.4 3.3 1 1 3 4 4 4 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF3391 PF11871.8 KFM27230.1 - 4.6 7.8 7.6 11 6.6 5.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3391) V-ATPase_G_2 PF16999.5 KFM27230.1 - 7.9 6.9 17.3 1.4 9.4 1.9 3.1 1 1 2 3 3 3 0 Vacuolar (H+)-ATPase G subunit TT_ORF1 PF02956.14 KFM27231.1 - 6.9 5.2 14.6 6.8 5.2 14.6 1.1 1 0 0 1 1 1 0 TT viral orf 1 Apolipoprotein PF01442.18 KFM27232.1 - 1.6e-06 28.2 12.3 0.023 14.6 0.5 4.7 3 2 0 3 3 3 3 Apolipoprotein A1/A4/E domain FumaraseC_C PF10415.9 KFM27232.1 - 0.15 12.5 4.2 15 6.1 0.1 3.9 3 0 0 3 3 3 0 Fumarase C C-terminus Kelch_3 PF13415.6 KFM27234.1 - 0.1 12.9 0.2 1.5 9.2 0.0 2.4 2 0 0 2 2 2 0 Galactose oxidase, central domain Ribosomal_L28e PF01778.17 KFM27235.1 - 7.1e-22 78.3 0.5 1.1e-21 77.7 0.5 1.3 1 0 0 1 1 1 1 Ribosomal L28e protein family CTP_transf_like PF01467.26 KFM27235.1 - 2.9e-11 43.7 0.0 5e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like HSP70 PF00012.20 KFM27236.1 - 3e-265 881.1 4.0 3.7e-265 880.8 4.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFM27236.1 - 1e-12 47.6 0.1 2.7e-10 39.6 0.0 2.6 2 1 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 KFM27236.1 - 2.9e-06 27.6 1.1 0.085 13.3 0.0 3.8 3 2 0 3 3 3 2 Cell division protein FtsA DUF810 PF05664.11 KFM27238.1 - 2.2e-38 132.3 0.0 4.3e-25 88.4 0.0 2.7 2 1 1 3 3 3 2 Plant family of unknown function (DUF810) dNK PF01712.19 KFM27239.1 - 3.3e-51 174.1 0.0 2.2e-50 171.4 0.0 1.9 2 0 0 2 2 2 1 Deoxynucleoside kinase AAA_18 PF13238.6 KFM27239.1 - 0.0021 18.6 0.0 0.53 10.8 0.0 3.1 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.6 KFM27239.1 - 0.004 17.3 0.0 0.21 11.7 0.0 2.8 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KFM27239.1 - 0.0068 16.1 0.0 0.22 11.2 0.0 2.4 2 0 0 2 2 2 1 Thymidylate kinase ABC_tran PF00005.27 KFM27239.1 - 0.036 14.6 0.0 0.066 13.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_17 PF13207.6 KFM27239.1 - 0.045 14.2 0.0 0.64 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KFM27239.1 - 0.063 13.3 0.0 0.23 11.5 0.0 1.8 1 1 1 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IIGP PF05049.13 KFM27239.1 - 0.2 10.7 0.0 0.35 9.9 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) HABP4_PAI-RBP1 PF04774.15 KFM27240.1 - 0.00028 21.7 2.7 0.00028 21.7 2.7 1.5 2 0 0 2 2 2 1 Hyaluronan / mRNA binding family Stm1_N PF09598.10 KFM27240.1 - 0.0064 17.3 8.9 0.026 15.4 8.9 2.1 1 1 0 1 1 1 1 Stm1 MitMem_reg PF13012.6 KFM27241.1 - 1.8e-10 41.2 0.0 2.5e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function ATG16 PF08614.11 KFM27243.1 - 5.8e-16 59.3 25.6 7.1e-16 59.0 25.6 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 KFM27243.1 - 0.0027 17.7 18.9 0.087 12.8 8.1 2.2 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Phage_GP20 PF06810.11 KFM27243.1 - 0.0074 16.1 7.2 0.0074 16.1 7.2 2.2 1 1 1 2 2 2 1 Phage minor structural protein GP20 Surfac_D-trimer PF09006.11 KFM27243.1 - 0.014 15.3 0.1 0.05 13.5 0.1 2.1 1 1 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation DMPK_coil PF08826.10 KFM27243.1 - 0.024 14.8 2.7 0.024 14.8 2.7 3.4 2 1 0 3 3 3 0 DMPK coiled coil domain like CALCOCO1 PF07888.11 KFM27243.1 - 0.024 13.5 23.7 0.38 9.6 1.9 2.1 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4140 PF13600.6 KFM27243.1 - 0.034 14.6 5.5 0.034 14.6 5.5 3.5 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) MAD PF05557.13 KFM27243.1 - 0.043 12.2 17.6 0.059 11.7 17.6 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein AAA_13 PF13166.6 KFM27243.1 - 0.083 11.5 13.3 0.1 11.2 13.3 1.0 1 0 0 1 1 1 0 AAA domain LepB_GAP_N PF18172.1 KFM27243.1 - 0.095 12.6 2.4 0.43 10.5 1.7 1.9 1 1 1 2 2 2 0 LepB GAP domain N-terminal subdomain FlaC_arch PF05377.11 KFM27243.1 - 0.1 13.0 1.7 0.3 11.5 0.1 2.6 3 1 0 3 3 2 0 Flagella accessory protein C (FlaC) EF-hand_8 PF13833.6 KFM27243.1 - 0.16 11.9 0.0 0.43 10.5 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain pair DUF16 PF01519.16 KFM27243.1 - 0.16 12.4 5.9 0.86 10.1 5.9 2.5 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF3573 PF12097.8 KFM27243.1 - 0.18 10.6 0.3 0.25 10.1 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) YabA PF06156.13 KFM27243.1 - 0.29 11.8 7.1 1.9 9.1 1.5 3.0 1 1 1 2 2 2 0 Initiation control protein YabA bZIP_2 PF07716.15 KFM27243.1 - 0.44 10.7 14.6 4.7 7.4 0.7 3.8 3 1 1 4 4 4 0 Basic region leucine zipper V_ATPase_I PF01496.19 KFM27243.1 - 0.44 8.4 8.4 0.63 7.9 8.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF812 PF05667.11 KFM27243.1 - 0.5 9.2 17.2 0.74 8.6 17.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Syntaxin-6_N PF09177.11 KFM27243.1 - 0.55 10.8 9.5 0.37 11.4 3.6 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal BRE1 PF08647.11 KFM27243.1 - 0.55 10.3 14.9 0.1 12.7 3.6 3.0 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase Fib_alpha PF08702.10 KFM27243.1 - 0.66 10.1 4.6 0.96 9.6 3.6 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FUSC PF04632.12 KFM27243.1 - 0.71 8.3 28.1 0.022 13.3 16.4 2.0 1 1 1 2 2 2 0 Fusaric acid resistance protein family DUF1664 PF07889.12 KFM27243.1 - 1.1 9.2 7.0 0.26 11.3 3.2 1.9 2 1 0 2 2 1 0 Protein of unknown function (DUF1664) Rab_bind PF16704.5 KFM27243.1 - 1.3 9.1 6.5 0.47 10.5 1.0 2.6 2 0 0 2 2 2 0 Rab binding domain Not3 PF04065.15 KFM27243.1 - 1.5 8.2 9.4 0.91 8.9 4.7 2.0 1 1 2 3 3 3 0 Not1 N-terminal domain, CCR4-Not complex component ZapB PF06005.12 KFM27243.1 - 1.7 9.2 18.9 0.22 12.0 3.6 3.5 1 1 1 2 2 2 0 Cell division protein ZapB DivIVA PF05103.13 KFM27243.1 - 2.4 8.3 25.4 7.2 6.7 11.6 2.2 1 1 1 2 2 2 0 DivIVA protein BLOC1_2 PF10046.9 KFM27243.1 - 3.5 8.0 9.7 0.4 11.0 1.8 3.0 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG6_N PF17675.1 KFM27243.1 - 4.2 7.9 25.2 9.9e+02 0.2 25.2 2.9 1 1 0 1 1 1 0 Apg6 coiled-coil region FliD_N PF02465.18 KFM27243.1 - 4.3 8.1 9.9 0.84 10.4 0.4 2.5 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF4679 PF15728.5 KFM27243.1 - 5.3 6.0 5.3 1.3 8.0 1.9 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4679) DivIC PF04977.15 KFM27243.1 - 5.5 6.8 21.5 0.06 13.1 2.6 3.8 2 2 2 4 4 4 0 Septum formation initiator PI3K_P85_iSH2 PF16454.5 KFM27243.1 - 7.9 6.0 10.7 1.9 8.1 1.9 2.7 1 1 2 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain WD40 PF00400.32 KFM27244.1 - 5.3e-28 96.7 12.6 2.7e-05 24.9 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM27244.1 - 2.1e-09 37.6 0.8 0.63 10.4 0.0 5.7 1 1 6 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFM27244.1 - 0.012 14.3 0.1 3.1 6.3 0.0 3.4 2 1 2 4 4 4 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KFM27244.1 - 0.042 12.8 0.6 20 4.0 0.0 3.7 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 KFM27244.1 - 0.056 12.4 7.6 0.54 9.1 0.2 2.6 2 1 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain PT-TG PF14449.6 KFM27246.1 - 0.094 12.6 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 Pre-toxin TG RabGAP-TBC PF00566.18 KFM27247.1 - 3.2e-10 40.0 0.0 1.1e-09 38.3 0.0 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain EBV-NA1 PF02905.14 KFM27247.1 - 0.16 11.8 0.1 0.53 10.1 0.0 1.8 2 0 0 2 2 2 0 Epstein Barr virus nuclear antigen-1, DNA-binding domain DnaJ-X PF14308.6 KFM27248.1 - 3.7e-37 127.8 0.0 5e-37 127.4 0.0 1.1 1 0 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.31 KFM27248.1 - 3.5e-23 81.5 1.3 6.2e-23 80.7 1.3 1.4 1 0 0 1 1 1 1 DnaJ domain GIY-YIG PF01541.24 KFM27249.1 - 5.7e-13 49.0 0.0 8.7e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 GIY-YIG catalytic domain PHD PF00628.29 KFM27249.1 - 0.0015 18.3 1.7 0.0027 17.6 1.7 1.4 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 KFM27249.1 - 0.0021 17.9 1.0 0.004 17.0 1.0 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KFM27249.1 - 0.043 14.1 0.6 0.087 13.2 0.6 1.5 1 0 0 1 1 1 0 C1 domain Zf_RING PF16744.5 KFM27249.1 - 0.056 13.6 0.4 0.13 12.4 0.4 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger BCDHK_Adom3 PF10436.9 KFM27250.1 - 2.4e-55 186.8 0.1 3.2e-55 186.4 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KFM27250.1 - 4.7e-13 49.6 0.0 8.5e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KFM27250.1 - 0.016 15.0 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TENA_THI-4 PF03070.16 KFM27251.1 - 3.7e-10 40.0 0.0 5.3e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family TENA_THI-4 PF03070.16 KFM27252.1 - 3.1e-29 102.3 1.7 3.4e-29 102.2 1.7 1.0 1 0 0 1 1 1 1 TENA/THI-4/PQQC family ATP11 PF06644.11 KFM27253.1 - 3.3e-31 109.1 0.1 3.7e-31 108.9 0.1 1.0 1 0 0 1 1 1 1 ATP11 protein Kinesin PF00225.23 KFM27254.1 - 7.5e-89 297.9 0.0 1.2e-88 297.2 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFM27254.1 - 2e-13 50.5 0.0 3.5e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding Trimer_CC PF08954.11 KFM27254.1 - 3.1e-06 26.6 2.3 5.1e-05 22.8 2.3 3.3 1 0 0 1 1 1 1 Trimerisation motif Bac_DnaA PF00308.18 KFM27254.1 - 0.039 13.8 0.1 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 Bacterial dnaA protein Spc29 PF17082.5 KFM27254.1 - 0.094 12.5 2.5 0.082 12.7 0.4 2.0 2 0 0 2 2 2 0 Spindle Pole Component 29 Ribosomal_L4 PF00573.22 KFM27255.1 - 3.4e-51 173.7 0.3 4.3e-51 173.4 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Pur_ac_phosph_N PF16656.5 KFM27257.1 - 1.2e-18 67.5 0.0 3.5e-18 66.0 0.0 1.8 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 KFM27257.1 - 1.6e-15 58.2 0.0 2.9e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase fn3_PAP PF17808.1 KFM27257.1 - 6e-10 39.3 0.0 1.3e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Fn3-like domain from Purple Acid Phosphatase Metallophos_C PF14008.6 KFM27257.1 - 1.1e-09 39.0 0.0 2.2e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C AP2 PF00847.20 KFM27258.1 - 9.8e-09 35.3 0.2 1.9e-08 34.4 0.2 1.5 1 0 0 1 1 1 1 AP2 domain DUF1115 PF06544.12 KFM27259.1 - 0.00011 22.3 0.0 0.00012 22.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) Aminotran_3 PF00202.21 KFM27260.1 - 5.1e-84 282.3 0.0 6.7e-84 281.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III W2 PF02020.18 KFM27261.1 - 5.4e-21 74.5 2.5 1.7e-20 72.9 2.5 2.0 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon NTP_transferase PF00483.23 KFM27261.1 - 4.4e-10 39.6 0.0 8e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 KFM27261.1 - 2.2e-05 24.0 5.6 0.0079 15.9 0.4 3.7 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KFM27261.1 - 0.0025 17.5 2.3 0.0025 17.5 2.3 2.5 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.7 KFM27261.1 - 0.0063 16.9 0.2 0.017 15.5 0.2 1.8 1 0 0 1 1 1 1 MobA-like NTP transferase domain Aldolase PF01081.19 KFM27261.1 - 0.026 13.9 0.0 0.08 12.3 0.0 1.8 1 0 0 1 1 1 0 KDPG and KHG aldolase Fucokinase PF07959.12 KFM27261.1 - 0.1 11.5 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 L-fucokinase SPX PF03105.19 KFM27262.1 - 4e-09 36.9 5.4 0.0001 22.3 0.0 3.2 1 1 2 3 3 3 3 SPX domain CBFD_NFYB_HMF PF00808.23 KFM27262.1 - 7.3e-09 35.8 1.0 7.3e-09 35.8 1.0 2.5 2 1 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFM27262.1 - 4.4e-08 33.5 0.2 4.4e-08 33.5 0.2 2.1 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 KFM27262.1 - 0.015 15.3 0.1 0.047 13.7 0.0 1.8 2 0 0 2 2 2 0 Bromodomain associated CENP-T_C PF15511.6 KFM27262.1 - 0.031 14.4 0.2 0.089 12.9 0.0 1.8 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T histone fold LSM PF01423.22 KFM27263.1 - 1.2e-17 63.3 0.3 1.5e-17 63.1 0.3 1.1 1 0 0 1 1 1 1 LSM domain NAD_Gly3P_dh_N PF01210.23 KFM27263.1 - 0.033 14.2 0.0 0.037 14.0 0.0 1.0 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Hfq PF17209.3 KFM27263.1 - 0.041 13.5 0.1 0.059 13.0 0.1 1.4 1 1 0 1 1 1 0 Hfq protein Pep_deformylase PF01327.21 KFM27264.1 - 1.1e-47 161.6 0.0 1.3e-47 161.3 0.0 1.1 1 0 0 1 1 1 1 Polypeptide deformylase DUF4817 PF16087.5 KFM27264.1 - 0.079 12.8 0.0 0.28 11.0 0.0 1.9 3 0 0 3 3 3 0 Helix-turn-helix domain (DUF4817) RRM_1 PF00076.22 KFM27265.1 - 5.2e-10 39.0 0.0 1.2e-05 25.0 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KFM27265.1 - 0.012 15.9 0.0 0.045 14.0 0.0 1.9 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Methyltransf_16 PF10294.9 KFM27266.1 - 3.6e-18 65.9 0.0 8e-18 64.8 0.0 1.6 1 1 0 1 1 1 1 Lysine methyltransferase Med22 PF06179.12 KFM27266.1 - 0.00052 20.2 0.2 0.0013 18.9 0.2 1.6 1 1 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Methyltransf_23 PF13489.6 KFM27266.1 - 0.059 13.2 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KFM27266.1 - 0.16 11.5 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Elong-fact-P_C PF09285.11 KFM27267.1 - 0.0053 16.5 0.0 0.0069 16.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor P, C-terminal SNF2_N PF00176.23 KFM27269.1 - 2.7e-21 75.7 0.0 4.4e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFM27269.1 - 2.2e-13 50.5 0.0 3.7e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM27269.1 - 3.1e-05 24.1 0.0 0.00015 21.8 0.0 2.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFM27269.1 - 0.00039 20.2 0.0 0.00073 19.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 KFM27269.1 - 0.14 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DUF4106 PF13388.6 KFM27269.1 - 0.82 8.8 2.2 1.3 8.2 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) 2OG-FeII_Oxy_3 PF13640.6 KFM27270.1 - 7.1e-20 71.7 0.0 1e-19 71.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KFM27270.1 - 5.9e-07 29.9 0.0 9.6e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glyco_transf_25 PF01755.17 KFM27271.1 - 4.1e-10 39.9 0.0 6.7e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) PIG-U PF06728.13 KFM27272.1 - 8.8e-12 44.8 4.9 6.8e-11 41.8 5.5 2.0 2 1 0 2 2 2 1 GPI transamidase subunit PIG-U B3 PF02362.21 KFM27273.1 - 0.018 14.9 0.3 0.051 13.4 0.3 1.7 1 1 0 1 1 1 0 B3 DNA binding domain RHS PF03527.14 KFM27273.1 - 0.021 14.6 1.9 4.6 7.1 0.1 2.3 2 0 0 2 2 2 0 RHS protein DUF192 PF02643.15 KFM27273.1 - 0.069 13.3 0.0 0.097 12.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized ACR, COG1430 Cnd1 PF12717.7 KFM27274.1 - 3.8e-19 69.3 0.0 7.2e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 KFM27274.1 - 0.00039 19.7 0.1 0.00068 18.9 0.1 1.3 1 0 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain ATP_sub_h PF10775.9 KFM27274.1 - 0.038 14.0 0.0 0.17 11.9 0.0 2.1 2 0 0 2 2 2 0 ATP synthase complex subunit h HEAT PF02985.22 KFM27274.1 - 0.13 12.6 7.1 1.1 9.6 0.2 4.8 4 0 0 4 4 4 0 HEAT repeat CbbQ_C PF08406.10 KFM27274.1 - 0.17 12.2 2.5 0.44 10.8 0.6 2.8 2 0 0 2 2 2 0 CbbQ/NirQ/NorQ C-terminal Adaptin_N PF01602.20 KFM27274.1 - 0.18 10.3 0.2 0.28 9.7 0.2 1.2 1 0 0 1 1 1 0 Adaptin N terminal region Arm PF00514.23 KFM27274.1 - 1.8 8.7 4.5 4.6 7.4 0.6 3.0 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Thioesterase PF00975.20 KFM27276.1 - 4e-13 50.0 0.0 9.3e-13 48.8 0.0 1.5 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.7 KFM27276.1 - 3e-06 28.0 6.9 3e-06 28.0 6.9 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.20 KFM27276.1 - 0.02 14.5 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Putative esterase LIDHydrolase PF10230.9 KFM27276.1 - 0.16 11.5 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Tetraspanin PF00335.20 KFM27277.1 - 9e-05 22.3 20.1 0.01 15.6 18.6 2.1 2 0 0 2 2 2 2 Tetraspanin family Calc_CGRP_IAPP PF00214.19 KFM27277.1 - 0.13 12.6 0.0 0.13 12.6 0.0 1.7 3 0 0 3 3 3 0 Calcitonin / CGRP / IAPP family V4R PF02830.18 KFM27278.1 - 0.00083 19.3 0.1 0.001 19.0 0.1 1.1 1 0 0 1 1 1 1 V4R domain Pkinase PF00069.25 KFM27279.1 - 2.7e-44 151.5 0.0 5.9e-44 150.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM27279.1 - 3e-19 69.3 0.0 5.2e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFM27279.1 - 0.0034 17.3 0.0 0.0034 17.3 0.0 3.8 3 2 0 3 3 3 1 Phosphotransferase enzyme family TFIIA PF03153.13 KFM27279.1 - 0.11 12.5 12.7 0.2 11.6 12.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Kdo PF06293.14 KFM27279.1 - 0.11 11.8 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ketoacyl-synt PF00109.26 KFM27280.1 - 1.2e-199 660.6 45.4 1.5e-42 146.0 2.3 6.4 7 0 0 7 7 7 5 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KFM27280.1 - 1e-107 357.9 26.5 1.5e-25 90.2 0.2 5.6 5 0 0 5 5 5 5 KR domain Ketoacyl-synt_C PF02801.22 KFM27280.1 - 2.4e-92 305.0 17.4 3.2e-24 85.2 2.8 6.1 5 0 0 5 5 5 5 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 KFM27280.1 - 1.4e-53 179.1 23.2 5.3e-09 36.3 0.1 8.9 9 0 0 9 9 9 7 Phosphopantetheine attachment site Thioesterase PF00975.20 KFM27280.1 - 2.4e-15 57.3 0.1 5.3e-15 56.2 0.1 1.6 1 0 0 1 1 1 1 Thioesterase domain KAsynt_C_assoc PF16197.5 KFM27280.1 - 2.6e-15 56.8 0.0 0.0022 18.4 0.0 4.6 4 0 0 4 4 4 4 Ketoacyl-synthetase C-terminal extension PS-DH PF14765.6 KFM27280.1 - 1.2e-13 51.0 14.7 1.1e-05 24.8 0.0 5.3 5 0 0 5 5 5 4 Polyketide synthase dehydratase adh_short PF00106.25 KFM27280.1 - 3.8e-13 49.3 14.3 7.9e-11 41.8 0.0 4.4 5 0 0 5 5 5 2 short chain dehydrogenase AAA PF00004.29 KFM27280.1 - 1.5e-12 48.1 0.0 4.2e-11 43.4 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFM27280.1 - 2.3e-09 37.9 0.4 1.9e-08 34.9 0.0 3.0 2 0 0 2 2 2 1 AAA ATPase domain BAH PF01426.18 KFM27280.1 - 1.1e-08 34.9 0.0 1.9e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 BAH domain PHD PF00628.29 KFM27280.1 - 1.7e-08 34.2 6.3 3.7e-08 33.1 6.3 1.6 1 0 0 1 1 1 1 PHD-finger AAA_lid_10 PF17872.1 KFM27280.1 - 8.6e-06 25.8 0.1 1.8e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 AAA lid domain Thiolase_N PF00108.23 KFM27280.1 - 3.2e-05 23.4 19.4 0.014 14.7 0.3 5.4 5 0 0 5 5 5 2 Thiolase, N-terminal domain AAA_22 PF13401.6 KFM27280.1 - 3.7e-05 24.0 0.0 7.9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain ketoacyl-synt PF00109.26 KFM27281.1 - 1.4e-28 100.2 9.5 2.9e-21 76.2 9.2 2.8 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KFM27281.1 - 1.1e-25 90.6 0.6 2.4e-25 89.5 0.6 1.6 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 KFM27281.1 - 1.8e-24 86.0 0.4 6.1e-24 84.3 0.4 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 KFM27281.1 - 3e-12 46.4 0.1 5.8e-12 45.5 0.1 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.25 KFM27281.1 - 1.9e-07 30.7 0.0 3.5e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.25 KFM27281.1 - 3.4e-07 30.5 0.2 7.6e-07 29.4 0.2 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 KFM27281.1 - 0.00098 19.6 0.0 0.029 14.8 0.0 2.4 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension ketoacyl-synt PF00109.26 KFM27282.1 - 3.6e-46 157.8 0.7 6.4e-46 157.0 0.7 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KFM27282.1 - 3.8e-25 88.2 2.6 6.3e-25 87.5 2.6 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 KFM27282.1 - 0.0012 18.2 0.1 0.002 17.6 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.26 KFM27283.1 - 2e-47 161.9 1.7 5e-47 160.6 1.6 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KFM27283.1 - 2.1e-30 105.1 0.7 6.1e-30 103.7 0.7 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 KFM27283.1 - 4.3e-29 101.7 6.8 8.5e-29 100.7 6.8 1.5 1 0 0 1 1 1 1 KR domain PP-binding PF00550.25 KFM27283.1 - 2.1e-20 72.9 0.3 4.9e-12 46.0 0.2 2.5 2 0 0 2 2 2 2 Phosphopantetheine attachment site ADH_zinc_N PF00107.26 KFM27283.1 - 2.5e-06 27.5 2.6 2.5e-06 27.5 0.5 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFM27283.1 - 6.4e-05 24.0 0.4 0.0042 18.1 0.1 2.9 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ApbA PF02558.16 KFM27283.1 - 0.00091 18.9 0.3 0.0019 17.9 0.3 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA PS-DH PF14765.6 KFM27283.1 - 0.0021 17.4 4.0 0.0061 15.8 0.6 2.3 2 0 0 2 2 2 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 KFM27283.1 - 0.0073 16.8 0.0 0.021 15.3 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KFM27283.1 - 0.053 13.0 4.1 0.061 12.8 0.8 2.3 2 0 0 2 2 2 0 short chain dehydrogenase HEAT_PBS PF03130.16 KFM27283.1 - 1.9 9.4 5.6 30 5.7 0.8 3.9 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat ketoacyl-synt PF00109.26 KFM27284.1 - 2.5e-79 266.5 13.2 2.5e-40 138.6 2.7 2.6 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KFM27284.1 - 7.9e-34 116.2 9.7 3.5e-15 56.1 0.2 3.7 2 1 1 3 3 3 3 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 KFM27284.1 - 2.1e-27 96.2 2.9 3.9e-27 95.3 2.9 1.5 1 0 0 1 1 1 1 KR domain PP-binding PF00550.25 KFM27284.1 - 2.7e-11 43.7 0.0 5.9e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site PS-DH PF14765.6 KFM27284.1 - 1.2e-07 31.3 3.1 1.2e-07 31.3 3.1 2.9 2 1 0 2 2 2 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 KFM27284.1 - 0.012 16.0 0.5 0.29 11.6 0.1 2.4 2 0 0 2 2 2 0 Ketoacyl-synthetase C-terminal extension Ribosomal_L2_C PF03947.18 KFM27285.1 - 3e-47 159.9 5.3 5.4e-47 159.1 5.3 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain SBDS_C PF09377.10 KFM27285.1 - 1.5e-30 105.6 0.0 2.6e-30 104.8 0.0 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 KFM27285.1 - 7.1e-30 102.9 0.1 1.1e-29 102.4 0.1 1.3 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Ribosomal_L2 PF00181.23 KFM27285.1 - 2.1e-19 69.3 0.1 1.6e-18 66.4 0.0 2.5 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain MCD PF05292.11 KFM27286.1 - 0.14 11.7 0.1 0.17 11.4 0.1 1.0 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase C-terminal domain OrfB_Zn_ribbon PF07282.11 KFM27287.1 - 0.075 13.0 4.8 0.75 9.8 4.8 2.3 1 1 0 1 1 1 0 Putative transposase DNA-binding domain P5CR_dimer PF14748.6 KFM27288.1 - 2.7e-38 130.3 7.3 2.7e-38 130.3 7.3 2.6 2 1 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KFM27288.1 - 6.2e-16 58.8 0.2 6.2e-16 58.8 0.2 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KFM27288.1 - 3.5e-05 24.0 0.0 7.4e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 KFM27288.1 - 0.012 15.3 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 KFM27288.1 - 0.16 12.0 0.0 0.49 10.5 0.0 1.9 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AAA PF00004.29 KFM27289.1 - 3.4e-41 140.8 0.0 5.7e-41 140.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFM27289.1 - 7.8e-08 32.0 0.7 1.4e-07 31.2 0.7 1.4 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KFM27289.1 - 6.3e-07 29.3 0.0 1.5e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 KFM27289.1 - 1.8e-06 28.0 0.0 9.8e-06 25.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KFM27289.1 - 7.3e-05 23.0 0.0 0.00015 22.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KFM27289.1 - 7.7e-05 23.0 0.3 0.013 15.8 0.1 2.4 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 KFM27289.1 - 0.00021 20.6 0.0 0.00035 19.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 KFM27289.1 - 0.00054 20.4 0.2 0.0022 18.4 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 KFM27289.1 - 0.0009 19.0 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 KFM27289.1 - 0.007 16.1 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein Prot_ATP_OB_N PF17758.1 KFM27289.1 - 0.0075 15.9 0.2 0.035 13.7 0.0 2.1 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain ATPase PF06745.13 KFM27289.1 - 0.0077 15.6 0.2 0.44 9.9 0.1 2.4 1 1 1 2 2 2 1 KaiC AAA_3 PF07726.11 KFM27289.1 - 0.013 15.4 0.0 0.062 13.2 0.0 2.1 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 KFM27289.1 - 0.023 13.9 0.0 0.04 13.1 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain NB-ARC PF00931.22 KFM27289.1 - 0.025 13.8 0.2 0.52 9.4 0.1 2.2 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.22 KFM27289.1 - 0.031 14.7 0.0 0.063 13.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.26 KFM27289.1 - 0.036 13.8 0.1 0.12 12.1 0.0 1.8 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 KFM27289.1 - 0.053 13.1 0.4 0.3 10.6 0.2 2.1 1 1 1 2 2 2 0 AAA domain NACHT PF05729.12 KFM27289.1 - 0.063 13.2 0.1 0.17 11.8 0.0 1.7 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 KFM27289.1 - 0.074 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KFM27289.1 - 0.08 12.7 0.2 0.22 11.2 0.2 1.7 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 KFM27289.1 - 0.097 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Mg_chelatase PF01078.21 KFM27289.1 - 0.1 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KFM27289.1 - 0.11 12.7 0.1 0.54 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KFM27289.1 - 0.21 11.1 0.0 0.69 9.4 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region Nnf1 PF03980.14 KFM27290.1 - 3.1e-12 46.9 1.8 4.8e-12 46.2 1.8 1.3 1 0 0 1 1 1 1 Nnf1 RNA_pol_Rpb1_5 PF04998.17 KFM27291.1 - 2.6e-79 266.4 0.0 4.4e-79 265.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KFM27291.1 - 2.9e-52 177.2 0.0 4.7e-52 176.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 KFM27291.1 - 2.9e-30 105.7 0.0 8.9e-23 81.1 0.0 2.2 2 0 0 2 2 2 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 KFM27291.1 - 9.4e-29 100.4 0.0 1.8e-28 99.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KFM27291.1 - 3e-19 68.9 0.0 6.2e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 PAP_central PF04928.17 KFM27292.1 - 1.1e-85 286.6 0.0 1.6e-85 286.1 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KFM27292.1 - 2e-08 34.0 0.0 0.0023 17.6 0.0 2.4 2 0 0 2 2 2 2 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 KFM27292.1 - 5.9e-07 29.7 0.0 1.3e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 KFM27292.1 - 0.00011 22.0 0.0 0.00018 21.3 0.0 1.3 1 0 0 1 1 1 1 Nrap protein PAP/OAS-like domain CARMIL_C PF16000.5 KFM27292.1 - 0.051 13.2 0.2 0.078 12.6 0.2 1.2 1 0 0 1 1 1 0 CARMIL C-terminus Trehalase PF01204.18 KFM27293.1 - 1.2e-141 473.1 0.0 1.5e-141 472.8 0.0 1.0 1 0 0 1 1 1 1 Trehalase Glyco_hydro_63 PF03200.16 KFM27293.1 - 0.0082 14.9 0.0 0.56 8.9 0.0 2.6 3 0 0 3 3 3 2 Glycosyl hydrolase family 63 C-terminal domain GDE_C PF06202.14 KFM27293.1 - 0.087 11.7 0.1 0.15 11.0 0.1 1.5 1 1 0 1 1 1 0 Amylo-alpha-1,6-glucosidase SNase PF00565.17 KFM27295.1 - 9.1e-52 174.1 2.2 4.7e-11 43.1 0.0 6.0 5 1 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 KFM27295.1 - 5.9e-16 58.6 0.0 1.6e-15 57.2 0.0 1.6 2 0 0 2 2 2 1 Tudor domain LEA_2 PF03168.13 KFM27295.1 - 0.023 15.2 0.7 2.1 8.9 0.0 3.4 4 0 0 4 4 4 0 Late embryogenesis abundant protein Gar1 PF04410.14 KFM27297.1 - 2.9e-31 108.3 0.2 4.9e-31 107.6 0.2 1.2 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Ribosomal_L16 PF00252.18 KFM27297.1 - 1.9e-29 102.3 1.1 3.3e-29 101.6 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L16p/L10e Utp12 PF04003.12 KFM27297.1 - 0.033 14.5 0.0 0.055 13.8 0.0 1.3 1 0 0 1 1 1 0 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KFM27297.1 - 0.092 13.1 0.0 1.6 9.1 0.0 3.0 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain HLH PF00010.26 KFM27298.1 - 1.1e-10 41.3 0.1 3e-10 39.9 0.0 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain ACT PF01842.25 KFM27298.1 - 3.2e-06 26.8 0.1 2e-05 24.3 0.1 2.2 2 0 0 2 2 2 1 ACT domain ACT_4 PF13291.6 KFM27298.1 - 0.0092 16.6 0.1 0.023 15.3 0.0 1.6 2 0 0 2 2 2 1 ACT domain Arf PF00025.21 KFM27299.1 - 3.7e-64 215.4 0.0 4.1e-64 215.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KFM27299.1 - 3e-13 49.6 0.0 3.9e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KFM27299.1 - 1.4e-11 44.7 0.0 1.9e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KFM27299.1 - 5.9e-11 42.1 0.4 9.4e-06 25.0 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KFM27299.1 - 1.3e-10 41.1 0.0 1.6e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KFM27299.1 - 4e-08 33.4 0.0 5.8e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFM27299.1 - 2.1e-07 30.5 0.0 2.6e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFM27299.1 - 0.00022 20.8 0.0 0.0069 15.9 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KFM27299.1 - 0.009 15.6 0.1 0.014 14.9 0.1 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B cobW PF02492.19 KFM27299.1 - 0.0097 15.5 0.0 0.44 10.1 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 KFM27299.1 - 0.087 13.1 0.1 0.61 10.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 KFM27299.1 - 0.12 12.4 0.1 0.24 11.4 0.1 1.4 1 1 0 1 1 1 0 Dynamin family MSP PF01716.18 KFM27301.1 - 2.1e-100 334.9 0.4 2.6e-100 334.6 0.4 1.1 1 0 0 1 1 1 1 Manganese-stabilising protein / photosystem II polypeptide Pkinase PF00069.25 KFM27303.1 - 3.7e-51 174.0 0.0 1.6e-31 109.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFM27303.1 - 4.1e-16 59.0 0.0 3.3e-07 29.9 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase IIGP PF05049.13 KFM27303.1 - 0.11 11.5 0.2 0.16 11.0 0.2 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) EF-hand_13 PF17958.1 KFM27304.1 - 3e-27 94.2 0.0 6.7e-27 93.1 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KFM27304.1 - 3.2e-20 72.4 1.2 5.3e-16 58.8 1.4 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KFM27304.1 - 0.0005 19.8 0.7 3.5 7.8 0.0 3.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 KFM27304.1 - 0.018 14.5 0.1 11 5.8 0.0 3.4 3 0 0 3 3 3 0 EF hand SPARC_Ca_bdg PF10591.9 KFM27304.1 - 0.37 11.1 2.4 22 5.4 0.3 2.9 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 KFM27304.1 - 1.1 9.2 3.2 8.4 6.3 0.6 3.0 3 0 0 3 3 3 0 EF hand FTHFS PF01268.19 KFM27305.1 - 5.2e-201 668.6 0.0 5.2e-112 374.9 0.0 4.0 2 2 1 3 3 3 3 Formate--tetrahydrofolate ligase CbiA PF01656.23 KFM27305.1 - 0.066 13.3 0.0 0.37 10.8 0.1 2.0 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Rdx PF10262.9 KFM27306.1 - 0.00072 19.7 0.0 0.00085 19.5 0.0 1.1 1 0 0 1 1 1 1 Rdx family ATPgrasp_N PF18130.1 KFM27307.1 - 3.4e-25 88.4 0.1 1.1e-24 86.8 0.1 1.9 1 0 0 1 1 1 1 ATP-grasp N-terminal domain ATP-grasp_4 PF13535.6 KFM27307.1 - 3.7e-16 59.1 0.0 6.4e-15 55.1 0.0 2.6 2 1 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.6 KFM27307.1 - 8.3e-11 41.7 0.3 8.2e-10 38.5 0.3 2.3 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 KFM27307.1 - 3.9e-09 36.7 0.0 1.9e-08 34.6 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 KFM27307.1 - 1.1e-07 31.6 0.0 0.0036 16.8 0.1 2.5 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.11 KFM27307.1 - 0.0001 21.9 0.0 0.00028 20.6 0.0 1.7 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp PF02222.22 KFM27307.1 - 0.00021 20.9 0.0 0.0068 16.0 0.0 2.5 3 0 0 3 3 3 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KFM27307.1 - 0.00072 19.2 0.0 0.044 13.3 0.0 2.3 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus GARS_A PF01071.19 KFM27307.1 - 0.0031 17.3 0.2 0.088 12.6 0.2 2.7 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.6 KFM27307.1 - 0.022 14.2 0.0 0.047 13.1 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain LAL_C2 PF18603.1 KFM27307.1 - 0.026 14.7 0.1 0.07 13.3 0.1 1.8 1 0 0 1 1 1 0 L-amino acid ligase C-terminal domain 2 ATPgrasp_N PF18130.1 KFM27308.1 - 4.5e-20 72.0 0.0 2.3e-19 69.7 0.0 2.3 1 1 0 1 1 1 1 ATP-grasp N-terminal domain ATP-grasp_4 PF13535.6 KFM27308.1 - 5.3e-18 65.1 0.0 1.2e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.6 KFM27308.1 - 4.9e-10 39.3 0.0 8.5e-09 35.2 0.0 2.7 2 1 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 KFM27308.1 - 3.3e-09 37.0 0.0 1.6e-08 34.8 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 KFM27308.1 - 5.6e-07 29.3 0.0 5.4e-05 22.8 0.0 2.2 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain GARS_A PF01071.19 KFM27308.1 - 0.00011 22.1 0.0 0.055 13.2 0.0 3.0 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp PF02222.22 KFM27308.1 - 0.0005 19.7 0.0 0.0026 17.4 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KFM27308.1 - 0.00072 19.2 0.0 0.015 14.9 0.0 2.3 1 1 1 2 2 2 1 D-ala D-ala ligase C-terminus LAL_C2 PF18603.1 KFM27308.1 - 0.028 14.6 0.1 0.1 12.8 0.0 2.0 2 0 0 2 2 2 0 L-amino acid ligase C-terminal domain 2 ATPgrasp_ST PF14397.6 KFM27308.1 - 0.03 13.6 0.0 0.14 11.4 0.0 1.8 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp DnaJ PF00226.31 KFM27310.1 - 2.5e-10 40.3 0.0 4.8e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain PGBA_C PF15437.6 KFM27310.1 - 3.9 7.9 7.5 1.2 9.5 4.5 1.7 1 1 1 2 2 2 0 Plasminogen-binding protein pgbA C-terminal Snf7 PF03357.21 KFM27311.1 - 1.2e-16 60.8 14.2 1.2e-08 34.7 3.4 2.0 1 1 1 2 2 2 2 Snf7 DUF5593 PF18007.1 KFM27311.1 - 0.093 13.4 0.1 0.32 11.7 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5593) PspA_IM30 PF04012.12 KFM27311.1 - 0.75 9.3 11.3 14 5.2 11.3 2.1 1 1 0 1 1 1 0 PspA/IM30 family rRNA_proc-arch PF13234.6 KFM27312.1 - 1.5e-54 185.7 0.0 4.1e-54 184.3 0.0 1.7 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.12 KFM27312.1 - 3.1e-48 163.5 2.4 6.6e-48 162.5 2.4 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 KFM27312.1 - 1.2e-16 61.0 0.0 2.6e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM27312.1 - 2.2e-06 27.9 0.0 2.7e-05 24.5 0.0 2.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM27312.1 - 0.00013 22.0 0.0 0.00023 21.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 KFM27312.1 - 0.049 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ECR1_N PF14382.6 KFM27313.1 - 2.2e-06 27.4 0.3 7e-06 25.7 0.3 1.9 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 KFM27313.1 - 8.8e-05 22.8 0.2 0.00017 21.9 0.2 1.5 1 0 0 1 1 1 1 KH domain IRK_C PF17655.1 KFM27314.1 - 6.8e-43 146.3 0.0 6.7e-25 87.7 0.0 2.2 2 0 0 2 2 2 2 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KFM27314.1 - 7.2e-10 38.8 7.9 5.1e-09 36.1 7.9 2.0 1 1 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 KFM27314.1 - 0.045 13.7 10.5 0.085 12.8 10.5 1.4 1 0 0 1 1 1 0 Ion channel DUF3533 PF12051.8 KFM27314.1 - 0.76 8.6 7.2 1.2 8.0 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Tubulin PF00091.25 KFM27315.1 - 3.9e-24 86.0 9.5 2.5e-18 67.0 1.0 3.1 1 1 2 3 3 3 3 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.8 KFM27315.1 - 5.3e-24 84.4 0.3 1.5e-23 82.9 0.0 1.9 2 0 0 2 2 2 1 FtsZ family, C-terminal domain NAD_binding_10 PF13460.6 KFM27315.1 - 0.037 13.9 0.5 0.082 12.8 0.5 1.5 1 0 0 1 1 1 0 NAD(P)H-binding Tubulin_2 PF13809.6 KFM27315.1 - 0.19 10.9 5.6 0.11 11.7 1.5 2.3 2 0 0 2 2 2 0 Tubulin like TRM PF02005.16 KFM27316.1 - 3.6e-119 398.3 0.0 4.7e-119 397.9 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 KFM27316.1 - 0.0045 16.8 0.0 0.0066 16.2 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 KFM27316.1 - 0.071 13.8 0.0 0.15 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 KFM27316.1 - 0.094 12.4 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DUF1731 PF08338.11 KFM27317.1 - 1.3e-18 66.6 0.2 4.2e-18 64.9 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1731) Epimerase PF01370.21 KFM27317.1 - 5.4e-12 45.7 0.0 7.5e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFM27317.1 - 1.6e-05 24.9 0.0 2.5e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KFM27317.1 - 0.00015 21.4 0.0 0.00024 20.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KFM27317.1 - 0.0038 16.7 0.0 0.04 13.3 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KFM27317.1 - 0.049 12.7 0.0 0.51 9.4 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain NAD_binding_4 PF07993.12 KFM27317.1 - 0.11 11.6 0.0 3.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Male sterility protein 3HCDH_N PF02737.18 KFM27317.1 - 0.22 11.4 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Aminotran_4 PF01063.19 KFM27318.1 - 5.1e-27 95.2 0.0 1.5e-22 80.5 0.0 2.1 2 0 0 2 2 2 2 Amino-transferase class IV Hydrolase_3 PF08282.12 KFM27320.1 - 2.2e-39 135.7 0.0 1.1e-24 87.6 0.0 2.1 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase UPF0054 PF02130.17 KFM27320.1 - 6.1e-35 119.8 0.0 8.7e-35 119.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 S6PP PF05116.13 KFM27320.1 - 1.5e-12 47.6 0.1 4.7e-09 36.1 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 KFM27320.1 - 8e-10 39.4 2.2 0.018 15.4 0.0 3.2 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFM27320.1 - 5.7e-07 30.1 6.8 0.0037 17.7 0.8 3.5 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KFM27320.1 - 0.0076 16.3 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KFM27320.1 - 0.13 12.3 0.0 12 5.9 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF1681 PF07933.14 KFM27321.1 - 6.3e-27 94.1 0.1 4.1e-22 78.5 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1681) DIL PF01843.19 KFM27322.1 - 1.4e-08 35.0 0.0 2.7e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 DIL domain PI3_PI4_kinase PF00454.27 KFM27324.1 - 7.5e-22 78.3 0.0 1.5e-20 74.1 0.0 2.2 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 KFM27324.1 - 7e-08 32.1 0.2 1.6e-07 31.0 0.2 1.6 1 0 0 1 1 1 1 FATC domain TPR_1 PF00515.28 KFM27326.1 - 4.6e-06 26.2 0.9 0.00066 19.4 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat CS PF04969.16 KFM27326.1 - 0.00011 23.2 0.0 0.0002 22.3 0.0 1.3 1 0 0 1 1 1 1 CS domain TPR_2 PF07719.17 KFM27326.1 - 0.00032 20.6 13.2 0.00055 19.8 0.4 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFM27326.1 - 0.0047 17.5 3.9 0.0047 17.5 3.9 4.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFM27326.1 - 0.12 12.6 0.7 5.7 7.4 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFM27326.1 - 0.39 10.7 3.7 0.28 11.1 1.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat A_deaminase PF00962.22 KFM27327.1 - 2e-105 352.8 0.0 1.1e-104 350.3 0.0 2.0 1 1 0 1 1 1 1 Adenosine/AMP deaminase SSXRD PF09514.10 KFM27327.1 - 0.031 13.9 0.1 0.33 10.6 0.0 2.5 2 0 0 2 2 2 0 SSXRD motif Iso_dh PF00180.20 KFM27328.1 - 9.6e-76 255.2 0.0 1.1e-75 254.9 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phe_ZIP PF08916.11 KFM27328.1 - 0.057 14.1 0.3 1.4 9.7 0.1 2.4 2 0 0 2 2 2 0 Phenylalanine zipper NTP_transf_6 PF06042.11 KFM27328.1 - 0.14 12.0 0.1 0.31 10.9 0.1 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase ATG16 PF08614.11 KFM27329.1 - 0.011 16.0 0.6 0.017 15.3 0.6 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Bap31_Bap29_C PF18035.1 KFM27329.1 - 0.1 12.6 0.4 3.1 7.9 0.3 2.4 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain HOOK PF05622.12 KFM27329.1 - 0.12 10.5 0.5 0.16 10.1 0.5 1.1 1 0 0 1 1 1 0 HOOK protein Fez1 PF06818.15 KFM27329.1 - 0.18 12.3 0.0 0.26 11.7 0.0 1.2 1 0 0 1 1 1 0 Fez1 Sec62 PF03839.16 KFM27331.1 - 2.5e-18 66.4 0.1 3.2e-18 66.0 0.1 1.1 1 0 0 1 1 1 1 Translocation protein Sec62 Hexapep_2 PF14602.6 KFM27332.1 - 1e-12 47.6 0.9 1e-08 34.8 0.7 2.4 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 KFM27332.1 - 9.4e-12 44.2 3.9 1.7e-09 37.0 1.3 2.7 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 KFM27332.1 - 1.1e-08 35.1 0.2 2.4e-08 34.1 0.2 1.5 1 0 0 1 1 1 1 Maltose acetyltransferase FH2 PF02181.23 KFM27333.1 - 1.8e-77 261.0 0.0 2.3e-77 260.6 0.0 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain DALR_1 PF05746.15 KFM27333.1 - 0.2 11.9 0.4 0.48 10.6 0.4 1.6 1 0 0 1 1 1 0 DALR anticodon binding domain Peptidase_S8 PF00082.22 KFM27334.1 - 3.1e-32 112.0 0.0 5.1e-32 111.3 0.0 1.3 1 0 0 1 1 1 1 Subtilase family Sacchrp_dh_NADP PF03435.18 KFM27335.1 - 1.4e-05 25.3 0.0 2.5e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DUF155 PF02582.14 KFM27336.1 - 9.1e-33 113.8 0.0 1.2e-32 113.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 LSM PF01423.22 KFM27337.1 - 2.6e-16 59.0 0.2 3.3e-16 58.7 0.2 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KFM27337.1 - 0.043 14.0 0.1 0.064 13.4 0.1 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Alpha-L-AF_C PF06964.12 KFM27338.1 - 2e-34 119.1 0.0 3.1e-34 118.5 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain CBM_4_9 PF02018.17 KFM27338.1 - 7.9e-06 26.2 0.0 2.1e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate binding domain Myb_DNA-binding PF00249.31 KFM27339.1 - 3.3e-20 72.0 10.4 1.4e-09 37.9 1.0 5.3 3 3 1 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFM27339.1 - 8.2e-17 61.2 6.3 1.1e-11 44.8 0.1 4.0 4 1 1 5 5 5 2 Myb-like DNA-binding domain HA PF03457.14 KFM27339.1 - 0.071 13.4 0.5 3.4 8.1 0.1 2.5 1 1 1 2 2 2 0 Helicase associated domain CW_7 PF08230.11 KFM27339.1 - 0.14 11.9 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 CW_7 repeat TPR_1 PF00515.28 KFM27340.1 - 3.5e-46 153.2 23.3 6.1e-05 22.7 0.0 9.5 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.17 KFM27340.1 - 5.8e-37 122.8 28.4 0.00075 19.4 0.0 9.6 9 0 0 9 9 9 8 Tetratricopeptide repeat STI1 PF17830.1 KFM27340.1 - 1.7e-32 111.2 6.4 1.2e-16 60.4 0.2 2.5 2 0 0 2 2 2 2 STI1 domain TPR_11 PF13414.6 KFM27340.1 - 3.3e-26 90.7 15.4 2.8e-08 33.3 0.2 7.5 4 2 3 7 7 7 5 TPR repeat TPR_16 PF13432.6 KFM27340.1 - 2e-21 76.4 29.1 8.7e-06 26.3 1.1 6.9 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 KFM27340.1 - 1.2e-16 61.0 18.9 0.0002 21.8 0.2 6.7 6 1 1 7 7 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 KFM27340.1 - 7.8e-16 58.1 26.6 3.5e-08 33.6 1.9 7.5 4 3 2 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFM27340.1 - 2.8e-14 52.6 23.4 0.26 12.2 0.0 9.5 4 3 6 10 10 9 6 Tetratricopeptide repeat TPR_8 PF13181.6 KFM27340.1 - 2.1e-13 49.3 25.9 0.0033 17.5 0.3 9.1 9 1 0 9 9 9 4 Tetratricopeptide repeat TPR_7 PF13176.6 KFM27340.1 - 1.1e-10 40.8 17.7 0.42 10.8 0.1 8.9 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_17 PF13431.6 KFM27340.1 - 1.7e-10 40.5 7.0 0.11 13.0 0.0 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFM27340.1 - 3.8e-10 39.8 7.0 0.04 14.1 0.1 5.0 3 3 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 KFM27340.1 - 4.8e-09 35.8 19.7 0.015 15.2 0.0 8.1 9 0 0 9 9 8 3 Tetratricopeptide repeat DUF3856 PF12968.7 KFM27340.1 - 1.4e-06 28.4 15.5 0.033 14.3 4.0 3.7 3 0 0 3 3 3 3 Domain of Unknown Function (DUF3856) ANAPC3 PF12895.7 KFM27340.1 - 2.8e-05 24.3 14.0 0.071 13.3 0.1 4.3 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KFM27340.1 - 0.00044 20.7 17.2 14 6.6 0.2 8.6 8 0 0 8 8 8 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFM27340.1 - 0.0076 16.3 2.7 87 3.3 0.0 6.0 6 1 1 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 KFM27340.1 - 2.2 8.4 25.3 1.8 8.7 1.6 6.2 5 2 0 5 5 5 0 MIT (microtubule interacting and transport) domain PPR PF01535.20 KFM27340.1 - 2.4 8.6 9.3 3.3 8.2 0.0 5.3 7 0 0 7 7 5 0 PPR repeat W2 PF02020.18 KFM27342.1 - 2e-19 69.5 1.3 3.3e-19 68.8 0.6 1.8 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon PI3Ka PF00613.20 KFM27342.1 - 0.088 12.2 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PknG_TPR PF16918.5 KFM27343.1 - 0.1 11.3 0.1 0.13 10.9 0.1 1.1 1 0 0 1 1 1 0 Protein kinase G tetratricopeptide repeat RETICULATA-like PF11891.8 KFM27344.1 - 1.4e-57 194.4 0.0 1.8e-57 194.0 0.0 1.1 1 0 0 1 1 1 1 Protein RETICULATA-related DUF4485 PF14846.6 KFM27345.1 - 1.7e-17 63.2 0.2 2.8e-17 62.5 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4485) RRM_1 PF00076.22 KFM27346.1 - 5.1e-60 199.2 0.0 6e-18 64.4 0.0 6.5 6 1 0 6 6 6 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFM27346.1 - 5e-06 26.3 0.0 0.27 11.1 0.0 4.0 4 0 0 4 4 4 2 Occluded RNA-recognition motif RRM_5 PF13893.6 KFM27346.1 - 0.00065 19.3 0.0 2.2 7.9 0.0 3.6 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFM27346.1 - 0.0035 17.4 0.0 16 5.7 0.0 4.7 5 0 0 5 5 5 1 RNA recognition motif RRM_Rrp7 PF17799.1 KFM27346.1 - 0.043 13.6 0.0 13 5.5 0.0 2.8 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain RRM_3 PF08777.11 KFM27346.1 - 0.081 13.0 0.0 8.4 6.5 0.0 3.2 2 0 0 2 2 2 0 RNA binding motif Fcf1 PF04900.12 KFM27347.1 - 7.5e-13 48.7 3.8 1e-08 35.4 1.2 2.3 1 1 1 2 2 2 2 Fcf1 PIN_9 PF18477.1 KFM27347.1 - 0.0038 17.5 0.0 0.0059 16.9 0.0 1.3 1 0 0 1 1 1 1 PIN like domain Colicin_V PF02674.16 KFM27348.1 - 0.021 14.8 1.7 0.063 13.3 1.7 1.6 1 1 0 1 1 1 0 Colicin V production protein Hum_adeno_E3A PF05393.11 KFM27348.1 - 0.048 13.7 0.0 0.08 12.9 0.0 1.3 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein GATase_6 PF13522.6 KFM27349.1 - 4.3e-13 49.6 0.0 2.1e-12 47.4 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KFM27349.1 - 5.6e-11 42.4 0.0 1.6e-10 40.9 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 KFM27349.1 - 6.9e-11 41.9 0.0 1.3e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 KFM27349.1 - 0.11 11.4 0.0 0.23 10.3 0.0 1.5 2 0 0 2 2 2 0 Glutamine amidotransferases class-II AP2 PF00847.20 KFM27352.1 - 1.5e-15 57.2 2.4 8.5e-08 32.3 0.1 2.5 2 0 0 2 2 2 2 AP2 domain DUF4680 PF15730.5 KFM27352.1 - 0.12 12.7 0.9 0.26 11.6 0.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4680) Cdd1 PF11731.8 KFM27352.1 - 0.21 11.8 0.0 0.35 11.1 0.0 1.2 1 0 0 1 1 1 0 Pathogenicity locus Aldo_ket_red PF00248.21 KFM27353.1 - 2.2e-51 174.8 0.0 2.8e-51 174.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family mTERF PF02536.14 KFM27353.1 - 0.0009 18.3 0.0 0.0014 17.6 0.0 1.2 1 0 0 1 1 1 1 mTERF HTH_18 PF12833.7 KFM27353.1 - 0.021 15.1 0.8 0.088 13.1 0.1 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain DAO PF01266.24 KFM27355.1 - 2.4e-09 37.3 6.7 4.4e-08 33.1 6.7 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Exo_endo_phos PF03372.23 KFM27356.1 - 6e-07 29.2 0.0 1.4e-06 28.0 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DnaJ_C PF01556.18 KFM27357.1 - 7.6e-36 123.4 0.0 1.1e-35 122.9 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 KFM27357.1 - 1e-14 54.6 16.1 1.8e-14 53.8 16.1 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KFM27357.1 - 0.00047 20.1 14.0 0.0035 17.3 1.3 2.8 2 1 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein zinc-ribbons_6 PF07191.12 KFM27357.1 - 0.0069 16.3 7.2 0.023 14.7 7.2 1.8 1 1 0 1 1 1 1 zinc-ribbons HypA PF01155.19 KFM27357.1 - 0.0097 15.9 5.9 0.42 10.7 0.7 2.5 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-CHY PF05495.12 KFM27357.1 - 0.078 13.5 3.8 0.33 11.5 3.8 1.9 1 1 1 2 2 2 0 CHY zinc finger Cytochrome_C7 PF14522.6 KFM27357.1 - 0.079 13.0 6.8 0.079 13.0 1.7 2.3 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c DUF5351 PF17302.2 KFM27357.1 - 8.1 6.7 20.5 7.3 6.9 0.7 4.4 4 0 0 4 4 4 0 Family of unknown function (DUF5351) IGPD PF00475.18 KFM27359.1 - 1.8e-65 219.6 0.6 2.6e-65 219.1 0.3 1.4 2 0 0 2 2 2 1 Imidazoleglycerol-phosphate dehydratase DUF3363 PF11843.8 KFM27359.1 - 0.052 12.5 0.2 0.093 11.7 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3363) Rrp15p PF07890.12 KFM27360.1 - 7.1e-14 52.3 3.8 1.5e-13 51.2 3.8 1.5 1 1 0 1 1 1 1 Rrp15p HAP2-GCS1 PF10699.9 KFM27361.1 - 3.1e-12 46.3 0.0 5.9e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Male gamete fusion factor HMMR_C PF15908.5 KFM27361.1 - 0.028 14.7 0.3 0.028 14.7 0.3 3.0 2 1 1 3 3 3 0 Hyaluronan mediated motility receptor C-terminal GAS PF13851.6 KFM27361.1 - 6.8 6.0 33.1 0.76 9.1 1.2 4.0 2 2 3 5 5 5 0 Growth-arrest specific micro-tubule binding UPF0121 PF03661.13 KFM27362.1 - 4.4e-05 23.0 0.1 8.1e-05 22.1 0.1 1.3 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0121) RmlD_sub_bind PF04321.17 KFM27363.1 - 3.5e-39 134.6 0.0 1.6e-38 132.4 0.0 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KFM27363.1 - 1.2e-21 77.3 0.0 3.1e-21 76.0 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFM27363.1 - 4.6e-11 42.7 0.0 1.3e-10 41.2 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KFM27363.1 - 7.7e-10 38.4 0.0 2e-09 37.0 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 KFM27363.1 - 0.00014 21.1 0.0 0.038 13.1 0.1 3.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 KFM27363.1 - 0.0071 16.3 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 KFM27363.1 - 0.017 14.7 0.7 0.034 13.7 0.1 1.8 3 0 0 3 3 3 0 NmrA-like family 3Beta_HSD PF01073.19 KFM27363.1 - 0.05 12.6 0.0 0.37 9.8 0.0 2.0 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Zip PF02535.22 KFM27364.1 - 2e-20 73.3 23.4 1.5e-15 57.3 13.0 2.0 1 1 1 2 2 2 2 ZIP Zinc transporter IBR PF01485.21 KFM27365.1 - 9.8e-23 80.2 28.9 1.7e-13 50.6 2.2 3.1 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain OB_NTP_bind PF07717.16 KFM27366.1 - 3.8e-25 88.1 0.0 7e-25 87.2 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KFM27366.1 - 1.2e-24 86.7 0.0 1.2e-24 86.7 0.0 2.0 2 0 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KFM27366.1 - 3e-12 46.9 0.0 5.9e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 KFM27366.1 - 1.1e-08 35.3 0.1 2.5e-08 34.1 0.1 1.5 1 0 0 1 1 1 1 S1 RNA binding domain AAA_22 PF13401.6 KFM27366.1 - 2.1e-05 24.8 0.1 5.8e-05 23.4 0.1 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 KFM27366.1 - 0.00052 19.8 0.2 0.001 18.9 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 KFM27366.1 - 0.0011 18.7 0.5 0.0011 18.7 0.5 2.1 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 KFM27366.1 - 0.0032 17.8 0.4 0.0081 16.5 0.4 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KFM27366.1 - 0.017 14.2 0.0 0.043 12.9 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF2075 PF09848.9 KFM27366.1 - 0.018 14.3 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 KFM27366.1 - 0.11 13.0 0.3 0.53 10.8 0.3 2.1 1 1 0 1 1 1 0 ABC transporter Microtub_bd PF16796.5 KFM27366.1 - 0.17 11.9 0.0 2.7 7.9 0.0 2.4 2 0 0 2 2 2 0 Microtubule binding AAA_16 PF13191.6 KFM27366.1 - 0.26 11.7 3.0 0.45 10.9 0.0 2.9 4 0 0 4 4 4 0 AAA ATPase domain Sugar_tr PF00083.24 KFM27367.1 - 6.3e-89 298.9 11.7 7.6e-89 298.6 11.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFM27367.1 - 3.7e-21 75.4 47.7 6.5e-18 64.8 19.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TauD PF02668.16 KFM27368.1 - 2.3e-42 145.6 0.1 3.6e-42 145.0 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Carb_anhydrase PF00194.21 KFM27369.1 - 7.9e-34 117.3 0.0 1.1e-33 116.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase SLATT_3 PF18184.1 KFM27369.1 - 0.0064 16.6 0.0 0.01 16.0 0.0 1.3 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain 3 Kinesin PF00225.23 KFM27370.1 - 5e-55 186.8 0.1 6.5e-55 186.4 0.1 1.1 1 0 0 1 1 1 1 Kinesin motor domain TPR_20 PF14561.6 KFM27370.1 - 0.21 11.9 2.2 1.4 9.3 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Sulfotransfer_3 PF13469.6 KFM27371.1 - 1.2e-31 110.8 0.0 8e-31 108.1 0.0 2.3 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 KFM27371.1 - 2e-07 30.8 0.0 3e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain TPR_12 PF13424.6 KFM27371.1 - 0.0086 16.3 17.0 0.39 11.0 3.5 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.14 KFM27371.1 - 0.14 12.8 0.1 0.14 12.8 0.1 7.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFM27371.1 - 1.4 9.1 8.7 18 5.6 0.6 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat ERG4_ERG24 PF01222.17 KFM27372.1 - 9.7e-77 258.5 5.6 1.2e-76 258.2 5.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Aminotran_4 PF01063.19 KFM27373.1 - 5.8e-28 98.3 0.0 3.7e-18 66.2 0.0 2.1 1 1 1 2 2 2 2 Amino-transferase class IV SUI1 PF01253.22 KFM27374.1 - 6.7e-19 68.2 1.0 1.1e-18 67.5 0.2 1.7 2 0 0 2 2 2 1 Translation initiation factor SUI1 RMMBL PF07521.12 KFM27376.1 - 9.3e-12 44.7 0.1 1.7e-11 43.9 0.1 1.3 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain PDEase_I PF00233.19 KFM27377.1 - 2.6e-52 177.9 0.0 3.9e-52 177.4 0.0 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Lactamase_B_2 PF12706.7 KFM27377.1 - 4.1e-12 46.1 0.0 7.8e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KFM27377.1 - 2.1e-10 40.9 0.0 7.1e-10 39.2 0.0 2.0 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 KFM27377.1 - 0.0032 17.4 0.0 0.008 16.1 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain HD PF01966.22 KFM27377.1 - 0.066 13.4 0.1 0.44 10.8 0.0 2.1 2 0 0 2 2 2 0 HD domain Fe-ADH PF00465.19 KFM27378.1 - 5.1e-125 417.1 5.4 6.1e-125 416.8 5.4 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KFM27378.1 - 6.5e-20 71.9 7.0 5.4e-11 42.7 0.0 2.1 1 1 1 2 2 2 2 Iron-containing alcohol dehydrogenase Abhydrolase_1 PF00561.20 KFM27379.1 - 2e-15 57.2 0.0 3.7e-13 49.7 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 KFM27379.1 - 4.7e-15 54.9 0.0 7.7e-15 54.2 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 KFM27379.1 - 2.4e-07 30.3 0.0 0.00012 21.5 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 VirJ PF06057.11 KFM27379.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) TPT PF03151.16 KFM27381.1 - 1.6e-21 76.9 9.4 2.1e-21 76.5 9.4 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KFM27381.1 - 5.5e-05 23.4 34.7 0.0051 17.0 17.7 3.3 3 1 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.15 KFM27381.1 - 0.0002 20.7 0.4 0.00035 19.8 0.4 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter PUNUT PF16913.5 KFM27381.1 - 0.00023 20.5 8.9 0.00032 20.0 8.9 1.3 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport UAA PF08449.11 KFM27381.1 - 0.0035 16.6 9.9 0.017 14.3 9.9 1.9 1 1 0 1 1 1 1 UAA transporter family DUF2530 PF10745.9 KFM27381.1 - 0.07 13.4 0.7 0.07 13.4 0.7 3.8 2 2 2 4 4 4 0 Protein of unknown function (DUF2530) Ribosomal_L3 PF00297.22 KFM27382.1 - 1.4e-173 577.1 12.2 1.6e-173 576.9 12.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 AAA_24 PF13479.6 KFM27382.1 - 0.017 14.8 0.3 0.071 12.8 0.2 1.9 2 0 0 2 2 2 0 AAA domain V-ATPase_G PF03179.15 KFM27383.1 - 6.3e-28 97.4 14.3 6.9e-28 97.3 14.3 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit OmpH PF03938.14 KFM27383.1 - 0.052 13.9 12.1 0.059 13.7 12.1 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4192 PF13830.6 KFM27383.1 - 0.9 9.5 8.7 1 9.4 8.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) ATP-synt_B PF00430.18 KFM27383.1 - 1.1 9.3 19.4 4.5 7.4 19.4 1.7 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) RNase_J_C PF17770.1 KFM27383.1 - 1.5 10.0 6.0 8.8 7.5 0.3 2.1 2 0 0 2 2 2 0 Ribonuclease J C-terminal domain DUF883 PF05957.13 KFM27383.1 - 6.1 7.5 14.7 18 6.0 1.6 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Presenilin PF01080.17 KFM27383.1 - 6.6 5.4 6.4 7.6 5.2 6.4 1.0 1 0 0 1 1 1 0 Presenilin TMPIT PF07851.13 KFM27383.1 - 6.7 5.9 5.9 7 5.8 5.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein Ribosomal_S5 PF00333.20 KFM27385.1 - 2.9e-23 81.6 6.5 5.4e-23 80.8 6.5 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 KFM27385.1 - 1e-22 79.3 0.4 1e-22 79.3 0.4 1.7 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Peptidase_A22B PF04258.13 KFM27386.1 - 1.9e-40 139.2 1.0 6.5e-21 75.1 0.1 2.1 1 1 1 2 2 2 2 Signal peptide peptidase PA PF02225.22 KFM27386.1 - 0.00057 19.9 1.2 0.0012 18.8 0.4 2.0 2 0 0 2 2 2 1 PA domain MCM_lid PF17855.1 KFM27387.1 - 0.0008 19.8 0.0 0.0013 19.2 0.0 1.3 1 0 0 1 1 1 1 MCM AAA-lid domain Rieske PF00355.26 KFM27388.1 - 1.9e-09 37.3 1.5 2.6e-09 36.9 1.4 1.3 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 KFM27388.1 - 9e-05 22.4 0.0 0.00013 21.8 0.0 1.2 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Ferritin PF00210.24 KFM27389.1 - 1e-28 100.0 2.0 1.3e-28 99.7 2.0 1.1 1 0 0 1 1 1 1 Ferritin-like domain TFIID-18kDa PF02269.16 KFM27389.1 - 0.081 13.0 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit RRM_occluded PF16842.5 KFM27389.1 - 0.15 11.9 0.0 0.38 10.6 0.0 1.7 1 0 0 1 1 1 0 Occluded RNA-recognition motif Torsin PF06309.11 KFM27391.1 - 4.4e-08 33.3 0.0 7.8e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Torsin AAA_22 PF13401.6 KFM27391.1 - 0.002 18.4 0.0 0.018 15.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KFM27391.1 - 0.03 14.7 0.0 0.057 13.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFM27391.1 - 0.032 14.6 0.0 0.14 12.5 0.0 2.4 1 1 0 1 1 1 0 AAA ATPase domain UPF0122 PF04297.14 KFM27391.1 - 0.17 12.2 0.0 0.34 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like Adenylsucc_synt PF00709.21 KFM27392.1 - 1.2e-169 564.8 0.0 1.3e-169 564.6 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Na_Ca_ex PF01699.24 KFM27393.1 - 1e-33 116.5 34.7 2.7e-21 76.1 14.5 3.3 2 1 1 3 3 3 3 Sodium/calcium exchanger protein DnaJ_C PF01556.18 KFM27394.1 - 4.3e-36 124.2 0.0 5.6e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KFM27394.1 - 2.3e-22 78.9 0.7 3.4e-22 78.3 0.7 1.3 1 0 0 1 1 1 1 DnaJ domain FYRC PF05965.14 KFM27395.1 - 1.9e-05 24.7 0.0 0.00016 21.7 0.0 2.1 1 1 0 1 1 1 1 F/Y rich C-terminus TPR_11 PF13414.6 KFM27396.1 - 0.31 10.8 5.7 2.2 8.0 0.1 3.4 3 0 0 3 3 3 0 TPR repeat TPR_2 PF07719.17 KFM27396.1 - 5.9 7.3 9.4 4.4 7.7 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TFIIF_alpha PF05793.12 KFM27397.1 - 3.8e-15 55.5 17.5 7.7e-12 44.6 17.5 2.9 1 1 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC27 PF09507.10 KFM27397.1 - 0.17 11.2 9.7 0.26 10.7 9.7 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RNA_pol_Rpc4 PF05132.14 KFM27398.1 - 9.9e-13 48.8 5.2 3.9e-11 43.6 0.0 2.5 2 1 1 3 3 3 2 RNA polymerase III RPC4 LapA_dom PF06305.11 KFM27399.1 - 0.21 11.4 1.5 0.38 10.6 1.5 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain ANAPC4_WD40 PF12894.7 KFM27400.1 - 8.1e-08 32.5 0.1 0.039 14.2 0.0 3.9 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFM27400.1 - 2.9e-06 27.9 7.1 1.1 10.2 0.1 5.7 5 1 0 5 5 5 2 WD domain, G-beta repeat Methyltransf_1N PF02870.15 KFM27400.1 - 0.18 12.6 0.0 0.39 11.6 0.0 1.5 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain ANAPC4_WD40 PF12894.7 KFM27402.1 - 2.9e-11 43.5 0.0 0.00082 19.6 0.0 3.9 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFM27402.1 - 0.032 15.1 0.1 1.8e+02 3.3 0.0 4.5 4 0 0 4 4 4 0 WD domain, G-beta repeat RIC1 PF07064.13 KFM27403.1 - 1.8e-15 57.0 0.0 1.2e-08 34.7 0.0 2.1 1 1 1 2 2 2 2 RIC1 NTP_transferase PF00483.23 KFM27404.1 - 5.9e-45 153.8 0.0 7.4e-45 153.5 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Fucokinase PF07959.12 KFM27404.1 - 0.0048 15.9 0.1 1.8 7.4 0.1 2.4 1 1 0 2 2 2 2 L-fucokinase Hexapep PF00132.24 KFM27404.1 - 0.024 14.4 1.7 0.024 14.4 1.7 4.0 4 1 0 4 4 4 0 Bacterial transferase hexapeptide (six repeats) Ribosomal_L11_N PF03946.14 KFM27405.1 - 1.9e-21 75.6 0.1 2.8e-21 75.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 KFM27405.1 - 2e-18 66.6 0.2 4.5e-18 65.5 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain WD40 PF00400.32 KFM27407.1 - 3.4e-35 119.5 16.4 2e-09 37.9 1.1 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM27407.1 - 8.3e-32 109.4 0.0 4.6e-10 39.7 0.0 6.8 3 2 4 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFM27407.1 - 7.2e-07 29.3 0.0 0.0056 16.6 0.0 2.9 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 KFM27407.1 - 7.7e-07 28.9 0.1 1.5e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 LisH RAB3GAP2_N PF14655.6 KFM27407.1 - 0.025 13.9 0.0 0.049 12.9 0.0 1.4 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus IKI3 PF04762.12 KFM27407.1 - 0.096 10.7 0.1 1.2 7.0 0.0 2.4 2 1 1 3 3 3 0 IKI3 family Nucleoporin_N PF08801.11 KFM27407.1 - 0.18 10.5 0.0 1.5 7.4 0.0 2.0 2 0 0 2 2 2 0 Nup133 N terminal like Drf_DAD PF06345.11 KFM27408.1 - 0.063 13.3 0.6 0.36 11.0 0.6 2.5 1 0 0 1 1 1 0 DRF Autoregulatory Domain GerE PF00196.19 KFM27409.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_20 PF12840.7 KFM27409.1 - 0.26 11.4 5.9 5.4 7.1 0.3 3.6 3 0 0 3 3 3 0 Helix-turn-helix domain CLP_protease PF00574.23 KFM27410.1 - 6.5e-81 270.6 0.0 7.4e-81 270.4 0.0 1.0 1 0 0 1 1 1 1 Clp protease HVSL PF09749.9 KFM27411.1 - 4.2e-27 95.2 0.0 5.2e-27 94.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein DPBB_1 PF03330.18 KFM27411.1 - 3.7e-07 30.3 0.2 8.6e-07 29.2 0.2 1.6 1 0 0 1 1 1 1 Lytic transglycolase 2_5_RNA_ligase2 PF13563.6 KFM27411.1 - 3.5e-05 23.8 1.3 0.00012 22.0 0.9 1.9 1 1 1 2 2 2 2 2'-5' RNA ligase superfamily DUF1045 PF06299.12 KFM27411.1 - 0.03 14.3 1.1 0.48 10.4 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1045) Phage_tail_NK PF16532.5 KFM27411.1 - 0.033 13.8 0.0 0.068 12.8 0.0 1.4 1 0 0 1 1 1 0 Sf6-type phage tail needle knob or tip of some Caudovirales Flg_hook PF02120.16 KFM27411.1 - 0.07 13.0 0.0 0.25 11.2 0.0 2.0 1 1 0 1 1 1 0 Flagellar hook-length control protein FliK QWRF PF04484.12 KFM27412.1 - 4.1 7.1 8.0 7.2 6.3 8.0 1.4 1 1 0 1 1 1 0 QWRF family ubiquitin PF00240.23 KFM27414.1 - 1e-12 47.6 0.0 1.9e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KFM27414.1 - 5e-05 23.0 0.0 8.3e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KFM27414.1 - 0.0012 19.2 0.0 0.0031 17.9 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain IGPS PF00218.21 KFM27415.1 - 1.6e-74 250.3 0.0 2e-74 250.0 0.0 1.1 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase His_biosynth PF00977.21 KFM27415.1 - 0.0034 16.9 0.0 2.2 7.7 0.0 2.3 2 0 0 2 2 2 2 Histidine biosynthesis protein FMN_dh PF01070.18 KFM27415.1 - 0.029 13.4 1.5 3.3 6.7 0.2 2.2 2 0 0 2 2 2 0 FMN-dependent dehydrogenase DUF313 PF03754.13 KFM27415.1 - 0.23 11.7 0.0 0.47 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF313) Ribosomal_L22e PF01776.17 KFM27417.1 - 2e-47 160.1 3.4 2.5e-47 159.7 3.4 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family AdoMet_Synthase PF01941.19 KFM27417.1 - 0.041 12.7 0.7 0.048 12.4 0.7 1.1 1 0 0 1 1 1 0 S-adenosylmethionine synthetase (AdoMet synthetase) FadA PF09403.10 KFM27417.1 - 0.064 13.7 0.7 0.064 13.7 0.7 1.7 2 0 0 2 2 2 0 Adhesion protein FadA HK97-gp10_like PF04883.12 KFM27417.1 - 0.072 14.1 0.0 0.15 13.1 0.0 1.5 1 1 1 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component PUF PF00806.19 KFM27418.1 - 3.2e-49 161.9 0.2 1.5e-09 37.0 0.0 8.3 7 1 1 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 KFM27418.1 - 0.002 18.5 0.0 6.1 7.2 0.0 4.0 2 1 1 4 4 4 2 CPL (NUC119) domain EAP30 PF04157.16 KFM27420.1 - 8.8e-54 182.3 0.0 4.6e-53 179.9 0.0 1.8 1 1 0 1 1 1 1 EAP30/Vps36 family TPR_2 PF07719.17 KFM27421.1 - 4.2e-06 26.5 6.6 0.055 13.6 0.3 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFM27421.1 - 8.6e-06 25.4 1.8 0.12 12.2 0.2 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat Arm PF00514.23 KFM27421.1 - 0.0073 16.3 0.0 0.064 13.3 0.0 2.7 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat TPR_7 PF13176.6 KFM27421.1 - 0.008 16.1 0.5 8 6.8 0.3 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat SPO22 PF08631.10 KFM27421.1 - 0.087 12.3 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.6 KFM27421.1 - 0.78 10.1 13.7 3.4 8.0 4.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat SNF2_N PF00176.23 KFM27422.1 - 1.2e-46 159.1 0.0 2.8e-46 157.8 0.0 1.5 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFM27422.1 - 8e-07 29.4 0.0 2.1e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM27422.1 - 0.00034 20.7 0.0 0.00061 19.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KFM27422.1 - 0.0028 16.9 0.0 0.0042 16.3 0.0 1.2 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DUF2075 PF09848.9 KFM27422.1 - 0.026 13.8 0.0 0.041 13.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Pkinase PF00069.25 KFM27423.1 - 6.5e-71 238.8 0.0 8.1e-71 238.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM27423.1 - 7e-36 123.8 0.0 9.2e-36 123.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM27423.1 - 1.9e-06 27.5 0.0 8.7e-05 22.0 0.0 2.1 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 KFM27423.1 - 9.2e-06 25.2 0.0 1.5e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFM27423.1 - 0.0036 16.2 0.0 0.0056 15.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KFM27423.1 - 0.071 12.0 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Abhydrolase_6 PF12697.7 KFM27424.1 - 3.8e-26 93.1 17.1 4.6e-26 92.8 17.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFM27424.1 - 2.7e-11 43.2 0.0 3.4e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFM27424.1 - 2.8e-10 40.3 0.0 5e-10 39.5 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 KFM27424.1 - 2.1e-06 28.0 0.1 3e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.13 KFM27424.1 - 8.7e-06 25.7 0.7 1.4e-05 25.1 0.7 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 KFM27424.1 - 0.0013 18.6 0.1 0.0022 17.9 0.1 1.3 1 0 0 1 1 1 1 Lipase (class 3) Esterase PF00756.20 KFM27424.1 - 0.0015 18.3 0.1 0.0024 17.5 0.1 1.2 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.13 KFM27424.1 - 0.0022 17.8 0.0 0.0032 17.2 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF3089 PF11288.8 KFM27424.1 - 0.011 15.4 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) DUF2974 PF11187.8 KFM27424.1 - 0.057 13.0 0.0 0.079 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Chlorophyllase2 PF12740.7 KFM27424.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Syntaxin PF00804.25 KFM27425.1 - 2.8e-66 223.0 12.1 3.7e-66 222.6 12.1 1.2 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 KFM27425.1 - 7.5e-17 61.1 0.3 1.5e-16 60.1 0.3 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 KFM27425.1 - 6.3e-05 23.3 1.0 6.3e-05 23.3 1.0 1.7 2 0 0 2 2 2 1 Syntaxin-like protein OmpH PF03938.14 KFM27425.1 - 0.00087 19.6 4.3 0.00087 19.6 4.3 2.2 1 1 2 3 3 3 1 Outer membrane protein (OmpH-like) NPR1_interact PF15699.5 KFM27425.1 - 0.014 16.0 3.7 0.014 16.0 3.7 2.1 3 0 0 3 3 2 0 NPR1 interacting COG5 PF10392.9 KFM27425.1 - 0.035 14.3 2.0 0.074 13.2 0.5 2.3 2 2 1 3 3 3 0 Golgi transport complex subunit 5 YojJ PF10372.9 KFM27425.1 - 0.1 12.7 0.9 4.6 7.4 0.4 2.7 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus Equine_IAV_S2 PF06502.11 KFM27425.1 - 0.11 12.6 0.1 0.25 11.5 0.1 1.5 1 0 0 1 1 1 0 Equine infectious anaemia virus S2 protein Mto2_bdg PF12808.7 KFM27425.1 - 0.11 12.8 10.0 0.49 10.7 5.4 2.6 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region SF-assemblin PF06705.11 KFM27425.1 - 0.23 10.8 10.9 0.16 11.3 4.1 2.7 1 1 2 3 3 3 0 SF-assemblin/beta giardin FUSC PF04632.12 KFM27425.1 - 0.25 9.8 4.2 0.19 10.3 1.8 1.8 2 0 0 2 2 2 0 Fusaric acid resistance protein family DUF1664 PF07889.12 KFM27425.1 - 0.41 10.7 8.6 0.086 12.9 2.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Prominin PF05478.11 KFM27425.1 - 0.77 7.6 8.6 0.25 9.3 0.7 2.2 1 1 0 2 2 2 0 Prominin DUF737 PF05300.11 KFM27425.1 - 1.4 9.2 10.5 0.53 10.6 7.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF737) Synaptobrevin PF00957.21 KFM27425.1 - 2.1 8.2 5.2 2.5 8.0 0.2 2.8 2 1 1 3 3 3 0 Synaptobrevin Enkurin PF13864.6 KFM27425.1 - 3.3 8.2 8.3 22 5.6 0.1 3.3 2 1 1 3 3 3 0 Calmodulin-binding Spore_III_AB PF09548.10 KFM27425.1 - 3.7 7.6 8.8 3.3 7.8 0.2 2.7 1 1 1 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) SNAP PF14938.6 KFM27426.1 - 2.2e-98 329.2 9.5 2.5e-98 329.0 9.5 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_7 PF13176.6 KFM27426.1 - 8.8e-07 28.5 3.1 0.63 10.2 0.1 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFM27426.1 - 2.5e-06 27.1 8.2 0.31 11.2 0.1 4.9 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFM27426.1 - 3.4e-06 26.8 6.4 0.67 10.3 0.0 5.5 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFM27426.1 - 8.2e-05 23.0 5.7 2.5 8.9 0.2 5.6 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFM27426.1 - 0.00023 21.4 9.6 0.14 12.5 0.5 3.8 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFM27426.1 - 0.00057 19.6 5.0 0.99 9.3 1.8 4.2 4 1 0 4 4 4 1 Tetratricopeptide repeat PhageMin_Tail PF10145.9 KFM27426.1 - 0.013 15.4 0.8 0.36 10.6 0.0 2.4 2 0 0 2 2 2 0 Phage-related minor tail protein Ala_racemase_N PF01168.20 KFM27426.1 - 0.024 14.3 3.6 0.024 14.3 1.5 1.9 2 1 0 2 2 2 0 Alanine racemase, N-terminal domain Foie-gras_1 PF11817.8 KFM27426.1 - 0.026 14.1 3.0 0.19 11.3 0.3 2.2 1 1 0 2 2 2 0 Foie gras liver health family 1 TPR_14 PF13428.6 KFM27426.1 - 0.043 14.6 12.9 0.58 11.1 0.3 5.5 3 2 2 6 6 6 0 Tetratricopeptide repeat NSF PF02071.20 KFM27426.1 - 0.16 12.8 12.2 4.6 8.4 0.5 5.6 5 1 1 6 6 5 0 Aromatic-di-Alanine (AdAR) repeat ANAPC3 PF12895.7 KFM27426.1 - 0.37 11.0 4.2 2.2 8.6 0.2 3.3 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Sel1 PF08238.12 KFM27426.1 - 0.45 11.3 3.2 8.4 7.2 0.5 3.1 2 1 0 3 3 3 0 Sel1 repeat Spatacsin_C PF14649.6 KFM27426.1 - 0.82 8.7 5.6 34 3.4 5.3 2.4 1 1 0 1 1 1 0 Spatacsin C-terminus MIT PF04212.18 KFM27426.1 - 0.92 9.6 6.3 2.1 8.5 0.2 3.6 4 1 1 5 5 3 0 MIT (microtubule interacting and transport) domain TPR_16 PF13432.6 KFM27426.1 - 1.2 9.8 12.1 16 6.2 0.4 4.3 2 1 2 4 4 4 0 Tetratricopeptide repeat adh_short_C2 PF13561.6 KFM27427.1 - 1.1e-48 165.8 3.7 9.1e-47 159.6 3.7 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFM27427.1 - 2.7e-37 128.1 3.0 1.5e-30 106.1 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase Epimerase PF01370.21 KFM27427.1 - 0.008 15.7 0.2 0.021 14.3 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KFM27427.1 - 0.029 13.5 0.0 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain KR PF08659.10 KFM27427.1 - 0.081 12.8 9.3 0.13 12.1 2.2 2.7 2 1 1 3 3 3 0 KR domain Chloroa_b-bind PF00504.21 KFM27428.1 - 2e-49 168.2 0.1 2.7e-49 167.8 0.1 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Dus PF01207.17 KFM27429.1 - 1.9e-50 171.7 0.0 2.6e-50 171.3 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) PEP_mutase PF13714.6 KFM27429.1 - 0.014 14.9 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase LMBR1 PF04791.16 KFM27430.1 - 5.3e-50 170.8 0.0 6.3e-50 170.5 0.0 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein SpoVS PF04232.12 KFM27431.1 - 3.1e-35 119.8 0.2 6.6e-18 64.2 0.1 2.1 2 0 0 2 2 2 2 Stage V sporulation protein S (SpoVS) Sec7 PF01369.20 KFM27432.1 - 1.8e-44 151.6 0.0 2.9e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain DCB PF16213.5 KFM27432.1 - 4.8e-15 55.7 0.0 9.2e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 KFM27432.1 - 6.3e-14 52.2 0.0 2.1e-06 27.7 0.0 2.6 1 1 1 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal FBPase PF00316.20 KFM27434.1 - 9.3e-70 233.9 0.0 1.2e-69 233.6 0.0 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 KFM27434.1 - 0.01 15.3 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Inositol monophosphatase family zf-CCCH_2 PF14608.6 KFM27435.1 - 0.0059 17.0 3.1 0.013 16.0 3.1 1.6 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger zf-CCCH PF00642.24 KFM27435.1 - 0.012 15.5 0.9 0.026 14.4 0.9 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFM27435.1 - 0.029 14.4 5.0 0.064 13.3 5.0 1.6 1 0 0 1 1 1 0 Zinc finger domain Senescence PF06911.12 KFM27437.1 - 2e-12 47.8 8.2 3.5e-12 47.0 8.2 1.5 1 0 0 1 1 1 1 Senescence-associated protein LDB19 PF13002.7 KFM27437.1 - 0.18 11.5 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 Arrestin_N terminal like Pro_isomerase PF00160.21 KFM27438.1 - 2.9e-11 43.9 0.0 4.2e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CBS PF00571.28 KFM27439.1 - 4.1e-19 68.8 0.1 8.6e-09 35.7 0.0 4.2 4 0 0 4 4 4 3 CBS domain DNA_ligase_A_M PF01068.21 KFM27440.1 - 1.8e-41 142.1 0.0 2.9e-41 141.4 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KFM27440.1 - 8.4e-33 114.1 0.0 6.7e-32 111.2 0.0 2.1 2 0 0 2 2 2 1 DNA ligase N terminus DRMBL PF07522.14 KFM27440.1 - 1.4e-17 63.8 0.0 2.7e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase DNA_ligase_A_C PF04679.15 KFM27440.1 - 9.2e-14 51.8 0.0 3e-13 50.2 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region UBA_4 PF14555.6 KFM27440.1 - 2.6e-05 23.9 0.0 7.9e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 UBA-like domain RMMBL PF07521.12 KFM27440.1 - 0.0073 16.2 0.0 0.025 14.5 0.0 1.8 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain EF-hand_6 PF13405.6 KFM27442.1 - 0.00012 21.8 0.0 0.48 10.5 0.0 3.2 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 KFM27442.1 - 0.00013 21.2 0.1 0.073 12.7 0.0 3.2 4 0 0 4 4 4 2 EF hand EF-hand_4 PF12763.7 KFM27442.1 - 0.00014 21.7 0.0 0.072 13.0 0.0 2.2 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.6 KFM27442.1 - 0.00022 20.6 0.1 0.19 11.3 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KFM27442.1 - 0.058 13.8 0.0 2.7 8.5 0.0 2.4 3 0 0 3 3 3 0 EF-hand domain pair RPN1_RPN2_N PF17781.1 KFM27443.1 - 1.1e-58 199.1 0.0 1.4e-58 198.8 0.0 1.1 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 KFM27443.1 - 1e-28 99.1 0.1 2e-28 98.2 0.1 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 KFM27443.1 - 1.2e-16 60.2 34.1 2e-06 28.0 0.1 9.7 11 0 0 11 11 11 5 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KFM27443.1 - 0.00076 19.8 3.2 0.015 15.7 0.2 4.4 3 2 2 5 5 5 2 HEAT repeats Peptidase_S8 PF00082.22 KFM27444.1 - 5.5e-28 98.1 14.0 9.7e-28 97.3 14.0 1.3 1 0 0 1 1 1 1 Subtilase family SAC3_GANP PF03399.16 KFM27444.1 - 0.0042 16.5 0.0 0.0064 15.9 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 KFM27444.1 - 0.032 14.2 0.0 0.062 13.3 0.0 1.4 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family PMSR PF01625.21 KFM27445.1 - 6.9e-58 195.2 0.7 9.3e-58 194.8 0.7 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase PglL_A PF15864.5 KFM27445.1 - 0.29 10.9 3.7 0.55 10.0 3.7 1.4 1 0 0 1 1 1 0 Protein glycosylation ligase Abhydrolase_1 PF00561.20 KFM27447.1 - 1.8e-20 73.7 0.4 4.4e-20 72.4 0.4 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFM27447.1 - 1.2e-14 55.5 10.9 1.8e-14 54.9 10.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFM27447.1 - 2.8e-14 53.0 0.3 2.8e-14 53.0 0.3 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KFM27447.1 - 0.00045 20.4 0.3 0.0012 19.0 0.3 1.7 1 0 0 1 1 1 1 Thioesterase domain Ndr PF03096.14 KFM27447.1 - 0.0026 16.5 0.0 0.0039 15.9 0.0 1.2 1 0 0 1 1 1 1 Ndr family Esterase_phd PF10503.9 KFM27447.1 - 0.0048 16.4 2.2 2.5 7.5 0.0 2.5 1 1 0 2 2 2 2 Esterase PHB depolymerase PGAP1 PF07819.13 KFM27447.1 - 0.019 14.7 0.1 0.033 13.9 0.1 1.3 1 0 0 1 1 1 0 PGAP1-like protein FSH1 PF03959.13 KFM27447.1 - 0.11 12.1 0.1 1.8 8.2 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) RNB PF00773.19 KFM27448.1 - 2.5e-96 322.8 0.0 3.1e-96 322.5 0.0 1.1 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 KFM27448.1 - 7.6e-06 25.9 0.0 1.6e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 KFM27448.1 - 0.017 15.3 0.0 0.031 14.4 0.0 1.4 1 0 0 1 1 1 0 Cold shock domain MdcG PF10620.9 KFM27448.1 - 0.018 14.8 0.6 19 4.9 0.0 3.4 3 0 0 3 3 3 0 Phosphoribosyl-dephospho-CoA transferase MdcG Galactosyl_T PF01762.21 KFM27449.1 - 8.6e-22 77.9 0.0 1.1e-19 71.0 0.0 2.4 1 1 0 1 1 1 1 Galactosyltransferase Glyco_tranf_2_3 PF13641.6 KFM27449.1 - 0.098 12.5 0.0 11 5.8 0.0 2.1 1 1 1 2 2 2 0 Glycosyltransferase like family 2 PsbR PF04725.12 KFM27450.1 - 7.4e-38 128.8 0.9 8.9e-38 128.6 0.9 1.1 1 0 0 1 1 1 1 Photosystem II 10 kDa polypeptide PsbR Metallophos_C PF14008.6 KFM27451.1 - 0.0015 19.3 1.9 0.0019 19.0 0.1 2.1 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C GST_C PF00043.25 KFM27452.1 - 3.6e-09 36.7 0.0 6.9e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFM27452.1 - 3.5e-06 26.9 0.1 5.5e-06 26.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KFM27452.1 - 2.8e-05 24.4 0.0 0.00011 22.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFM27452.1 - 5.9e-05 23.2 0.0 9.6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KFM27452.1 - 0.00061 20.1 0.0 0.0011 19.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Tom37 PF10568.9 KFM27452.1 - 0.14 12.5 0.0 0.58 10.5 0.0 1.9 1 1 1 2 2 2 0 Outer mitochondrial membrane transport complex protein PPR_2 PF13041.6 KFM27453.1 - 8.1e-13 48.3 0.0 5e-05 23.4 0.0 2.8 3 0 0 3 3 3 2 PPR repeat family GST_N PF02798.20 KFM27453.1 - 5.7e-10 39.4 0.0 1.3e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KFM27453.1 - 6.1e-10 39.4 0.0 1.3e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain PPR PF01535.20 KFM27453.1 - 3.9e-08 33.0 0.0 0.1 12.9 0.0 5.1 5 0 0 5 5 5 2 PPR repeat PPR_long PF17177.4 KFM27453.1 - 7.2e-08 32.1 0.0 1.3e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP GST_N_2 PF13409.6 KFM27453.1 - 4.4e-06 26.9 0.0 9.1e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFM27453.1 - 4.2e-05 23.7 0.0 8.4e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Smr PF01713.21 KFM27453.1 - 0.00046 20.5 0.4 0.0016 18.8 0.1 2.1 2 0 0 2 2 2 1 Smr domain PPR_3 PF13812.6 KFM27453.1 - 0.0064 16.5 0.0 1.5 9.0 0.0 2.7 3 0 0 3 3 3 1 Pentatricopeptide repeat domain GST_C_2 PF13410.6 KFM27453.1 - 0.0083 16.1 0.5 0.059 13.4 0.1 2.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFM27453.1 - 0.013 15.7 0.0 0.031 14.5 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain UBX PF00789.20 KFM27454.1 - 1.1e-21 76.8 0.0 1.8e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 KFM27454.1 - 1.6e-09 37.4 0.0 3.4e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain CUE PF02845.16 KFM27454.1 - 0.012 15.3 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 CUE domain Prok-E2_A PF14457.6 KFM27454.1 - 0.035 13.7 0.3 0.11 12.1 0.1 1.9 2 1 1 3 3 3 0 Prokaryotic E2 family A Thioredoxin_7 PF13899.6 KFM27454.1 - 0.21 11.8 0.0 0.21 11.8 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin-like MAS20 PF02064.15 KFM27454.1 - 7.7 6.6 7.9 15 5.7 7.9 1.5 1 0 0 1 1 1 0 MAS20 protein import receptor FemAB_like PF04339.12 KFM27455.1 - 8.6e-104 347.6 0.3 4.2e-99 332.2 0.1 2.0 1 1 1 2 2 2 2 Peptidogalycan biosysnthesis/recognition Acetyltransf_6 PF13480.7 KFM27455.1 - 1.7e-13 50.9 4.0 3.7e-13 49.9 3.2 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FemAB PF02388.16 KFM27455.1 - 0.00021 20.3 0.0 0.0004 19.4 0.0 1.4 1 0 0 1 1 1 1 FemAB family NAD_binding_1 PF00175.21 KFM27456.1 - 7.4e-27 94.2 0.0 1.3e-26 93.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KFM27456.1 - 0.0086 16.4 0.0 0.016 15.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain FAD_binding_1 PF00667.20 KFM27456.1 - 0.015 14.9 0.0 0.23 11.0 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain E1_dh PF00676.20 KFM27457.1 - 9.9e-91 303.8 0.0 1.2e-90 303.6 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KFM27457.1 - 0.015 14.5 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Lipase_bact_N PF12262.8 KFM27457.1 - 0.1 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence factor lipase N-terminal ACBP PF00887.19 KFM27458.1 - 3.6e-28 97.6 2.2 3.9e-28 97.5 2.2 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein HMG_box PF00505.19 KFM27459.1 - 3.2e-12 46.7 0.1 6.5e-12 45.7 0.1 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFM27459.1 - 3.4e-09 37.2 0.7 6.7e-09 36.2 0.7 1.4 1 0 0 1 1 1 1 HMG-box domain VitD-bind_III PF09164.10 KFM27459.1 - 0.12 12.4 0.0 0.36 10.8 0.0 1.8 2 0 0 2 2 2 0 Vitamin D binding protein, domain III SET PF00856.28 KFM27460.1 - 3.9e-20 72.9 0.1 1.7e-19 70.8 0.1 1.8 1 1 0 1 1 1 1 SET domain PTR2 PF00854.21 KFM27462.1 - 1.5e-111 373.1 1.1 1.9e-111 372.7 1.1 1.1 1 0 0 1 1 1 1 POT family Nefa_Nip30_N PF10187.9 KFM27463.1 - 1.7e-13 50.8 12.4 2.8e-13 50.1 12.4 1.3 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 FUSC PF04632.12 KFM27463.1 - 1.1 7.8 6.4 1.2 7.6 6.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Spore_III_AB PF09548.10 KFM27463.1 - 1.3 9.1 3.9 1.8 8.7 3.9 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) UCR_hinge PF02320.16 KFM27464.1 - 1.1e-20 73.6 4.8 1.3e-20 73.3 4.8 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein UPF0203 PF05254.12 KFM27464.1 - 0.2 11.9 6.1 2 8.7 5.9 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) PCI PF01399.27 KFM27465.1 - 3.6e-19 69.2 0.1 1.8e-18 67.0 0.0 2.1 2 0 0 2 2 2 1 PCI domain RPN5_C PF18098.1 KFM27465.1 - 7.5e-10 38.7 0.0 1.7e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain TPR_20 PF14561.6 KFM27465.1 - 0.0095 16.3 1.1 0.035 14.4 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat RPN7 PF10602.9 KFM27465.1 - 0.11 12.2 2.8 0.12 12.1 0.2 2.2 3 0 0 3 3 3 0 26S proteasome subunit RPN7 TPR_14 PF13428.6 KFM27465.1 - 0.15 13.0 6.7 48 5.2 0.3 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Las1 PF04031.13 KFM27465.1 - 0.21 11.7 1.5 0.98 9.5 0.5 2.2 2 0 0 2 2 2 0 Las1-like VWA_2 PF13519.6 KFM27466.1 - 4.1e-05 24.2 0.0 0.00041 21.0 0.0 2.2 1 1 0 1 1 1 1 von Willebrand factor type A domain TauD PF02668.16 KFM27466.1 - 0.0015 18.3 0.0 0.0022 17.9 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family VWA_3 PF13768.6 KFM27466.1 - 0.023 14.7 0.0 0.039 13.9 0.0 1.5 1 1 0 1 1 1 0 von Willebrand factor type A domain Ku_N PF03731.15 KFM27466.1 - 0.035 13.8 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 Ku70/Ku80 N-terminal alpha/beta domain NOG1_N PF17835.1 KFM27467.1 - 7.5e-41 139.8 0.0 2.2e-30 105.7 0.0 2.5 1 1 1 2 2 2 2 NOG1 N-terminal helical domain NOG1 PF06858.14 KFM27467.1 - 1.5e-27 95.1 0.2 3e-27 94.1 0.2 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 KFM27467.1 - 2.2e-23 82.0 0.5 5e-23 80.8 0.5 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.23 KFM27467.1 - 7.5e-19 67.9 0.0 1.3e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFM27467.1 - 1.8e-08 34.1 0.0 3.1e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KFM27467.1 - 0.00029 20.9 0.0 0.93 9.5 0.0 2.4 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.16 KFM27467.1 - 0.0017 17.7 0.0 0.0038 16.6 0.0 1.6 1 0 0 1 1 1 1 AIG1 family Roc PF08477.13 KFM27467.1 - 0.0095 16.1 0.0 0.078 13.2 0.0 2.2 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KFM27467.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 KFM27467.1 - 0.32 11.4 0.0 0.32 11.4 0.0 2.5 2 2 0 2 2 2 0 AAA ATPase domain IF3_C PF00707.22 KFM27468.1 - 4.3e-31 106.7 0.1 5.7e-31 106.3 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain Mito_carr PF00153.27 KFM27469.1 - 3.7e-60 199.9 0.7 4.3e-21 74.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein FKBP_C PF00254.28 KFM27470.1 - 7.8e-36 122.3 0.0 1.3e-35 121.6 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FAST_1 PF06743.15 KFM27470.1 - 3.9e-09 36.3 0.9 0.023 14.6 0.0 4.4 4 0 0 4 4 4 3 FAST kinase-like protein, subdomain 1 RAP PF08373.10 KFM27470.1 - 1.6e-06 28.1 0.0 2.6e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 RAP domain CRM1_repeat_3 PF18787.1 KFM27470.1 - 0.004 17.2 0.1 0.76 9.9 0.3 2.6 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 GTP_EFTU PF00009.27 KFM27471.1 - 9.4e-37 126.4 0.0 1.4e-36 125.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KFM27471.1 - 5.9e-18 64.7 0.0 1.6e-17 63.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KFM27471.1 - 5.1e-05 23.6 1.4 0.00018 21.8 1.4 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFM27471.1 - 0.0018 18.3 0.0 0.0035 17.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFM27471.1 - 0.19 11.2 0.0 0.66 9.5 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AIG1 PF04548.16 KFM27471.1 - 0.21 10.9 0.0 0.42 9.9 0.0 1.4 1 0 0 1 1 1 0 AIG1 family efThoc1 PF11957.8 KFM27472.1 - 8.7e-72 242.4 0.0 4.7e-35 121.2 0.0 2.0 1 1 1 2 2 2 2 THO complex subunit 1 transcription elongation factor HHH_2 PF12826.7 KFM27472.1 - 0.15 12.2 0.0 0.39 10.9 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif BAR PF03114.18 KFM27473.1 - 7.1e-07 29.1 2.5 9.9e-07 28.6 1.4 1.7 2 0 0 2 2 2 1 BAR domain TMF_DNA_bd PF12329.8 KFM27473.1 - 2.4 8.2 5.8 35 4.5 4.1 2.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Abhydrolase_1 PF00561.20 KFM27474.1 - 2.1e-19 70.2 0.0 2.3e-19 70.0 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFM27474.1 - 1.1e-10 42.6 0.4 1.2e-10 42.3 0.4 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFM27474.1 - 5.3e-10 39.0 0.0 6.3e-10 38.7 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KFM27474.1 - 0.00022 21.0 0.0 0.00025 20.9 0.0 1.1 1 0 0 1 1 1 1 PGAP1-like protein Ser_hydrolase PF06821.13 KFM27474.1 - 0.015 15.2 0.4 0.017 15.0 0.4 1.1 1 0 0 1 1 1 0 Serine hydrolase CDC27 PF09507.10 KFM27475.1 - 4.7e-21 75.7 0.0 6.2e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 GLE1 PF07817.13 KFM27476.1 - 9.5e-47 159.3 0.1 1.7e-46 158.4 0.0 1.4 2 0 0 2 2 2 1 GLE1-like protein 4HBT PF03061.22 KFM27478.1 - 0.0057 17.0 0.0 0.011 16.0 0.0 1.5 1 1 0 1 1 1 1 Thioesterase superfamily PsbQ PF05757.11 KFM27479.1 - 1e-38 133.1 5.8 1.2e-38 132.9 5.8 1.0 1 0 0 1 1 1 1 Oxygen evolving enhancer protein 3 (PsbQ) Metal_resist PF13801.6 KFM27479.1 - 0.52 10.5 9.8 0.79 9.9 1.6 2.3 1 1 1 2 2 2 0 Heavy-metal resistance Rab5ip PF07019.12 KFM27480.1 - 4e-14 53.0 8.4 5.4e-14 52.6 8.4 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) ATG16 PF08614.11 KFM27481.1 - 0.29 11.3 102.5 0.05 13.8 15.5 5.2 1 1 2 5 5 5 0 Autophagy protein 16 (ATG16) Choline_kinase PF01633.20 KFM27481.1 - 1.6 8.2 4.5 0.95 9.0 1.2 2.4 2 1 0 2 2 2 0 Choline/ethanolamine kinase DUF1664 PF07889.12 KFM27481.1 - 1.9 8.5 20.8 0.3 11.1 1.6 4.4 3 1 3 6 6 6 0 Protein of unknown function (DUF1664) Amino_oxidase PF01593.24 KFM27482.1 - 2.1e-08 33.9 0.2 6.6e-08 32.3 0.2 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Metallophos PF00149.28 KFM27483.1 - 2.6e-12 47.7 0.1 3.9e-12 47.1 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFM27483.1 - 3.6e-10 40.3 0.0 6.9e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Adap_comp_sub PF00928.21 KFM27484.1 - 3.5e-26 92.2 0.0 4.8e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KFM27484.1 - 0.00094 19.1 0.2 0.0014 18.6 0.2 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Ribosomal_L4 PF00573.22 KFM27485.1 - 1.7e-35 122.5 1.4 1.7e-35 122.5 1.4 1.8 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 KFM27485.1 - 5.4e-28 96.9 2.3 6.1e-28 96.7 0.2 2.0 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain CAP PF00188.26 KFM27486.1 - 1.5e-08 35.5 5.3 4.6e-08 33.9 5.5 1.6 1 1 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 KFM27487.1 - 3.7e-21 76.3 2.0 4.4e-21 76.0 2.0 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family RPN13_C PF16550.5 KFM27488.1 - 7.3e-08 32.6 0.1 1.4e-07 31.7 0.0 1.5 1 1 0 1 1 1 1 UCH-binding domain HEAT_PBS PF03130.16 KFM27488.1 - 2.3 9.1 6.6 1.1 10.2 0.9 3.0 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat TP_methylase PF00590.20 KFM27489.1 - 4.3e-47 160.8 3.5 5.7e-47 160.4 3.5 1.2 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Radical_SAM PF04055.21 KFM27489.1 - 0.012 16.0 0.0 0.027 14.8 0.0 1.5 1 0 0 1 1 1 0 Radical SAM superfamily NusB PF01029.18 KFM27490.1 - 6.5e-08 32.9 0.0 2.2e-07 31.2 0.0 1.8 2 0 0 2 2 2 1 NusB family Aminotran_1_2 PF00155.21 KFM27490.1 - 0.00059 19.1 0.0 0.00075 18.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Methyltr_RsmB-F PF01189.17 KFM27491.1 - 2.6e-43 148.0 0.0 1.8e-36 125.7 0.0 2.1 1 1 1 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KFM27491.1 - 0.095 12.8 0.0 1.4 9.0 0.0 2.0 1 1 1 2 2 2 0 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 KFM27491.1 - 0.19 11.6 0.0 0.42 10.4 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Pre-PUA PF17832.1 KFM27492.1 - 1.5e-25 89.7 0.0 2.1e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 KFM27492.1 - 1.6e-15 56.8 0.0 2.7e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 PUA domain DUF1947 PF09183.10 KFM27492.1 - 0.07 13.4 0.0 1.7 9.0 0.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF1947) MRP_L53 PF10780.9 KFM27493.1 - 2.4e-07 30.8 0.0 3.6e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 DsbD_2 PF13386.6 KFM27494.1 - 0.015 15.2 14.7 0.2 11.5 14.5 2.4 1 1 1 2 2 2 0 Cytochrome C biogenesis protein transmembrane region Paf1 PF03985.13 KFM27495.1 - 1.3e-52 179.2 0.0 2e-52 178.7 0.0 1.1 1 0 0 1 1 1 1 Paf1 SVS_QK PF10578.9 KFM27495.1 - 0.062 13.9 1.0 0.16 12.6 1.0 1.6 1 0 0 1 1 1 0 Seminal vesicle protein repeat zf-C4H2 PF10146.9 KFM27496.1 - 0.034 14.4 1.3 0.19 12.0 0.2 2.3 2 0 0 2 2 2 0 Zinc finger-containing protein SlyX PF04102.12 KFM27496.1 - 0.15 12.7 0.4 0.15 12.7 0.4 5.3 5 1 1 6 6 6 0 SlyX DUF4407 PF14362.6 KFM27496.1 - 0.47 9.8 33.5 0.28 10.5 10.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 KFM27496.1 - 3.1 7.3 10.1 71 2.8 10.1 2.2 1 1 0 1 1 1 0 Exonuclease VII, large subunit Fez1 PF06818.15 KFM27496.1 - 3.2 8.2 14.9 31 5.0 0.5 2.8 1 1 1 2 2 2 0 Fez1 HIP1_clath_bdg PF16515.5 KFM27496.1 - 3.7 8.2 22.8 1 10.0 3.1 4.3 4 1 0 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TFIIS_C PF01096.18 KFM27497.1 - 1.9e-18 66.0 3.8 2.7e-18 65.5 3.8 1.2 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.7 KFM27497.1 - 0.00069 19.5 0.5 0.0011 18.8 0.5 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Baculo_LEF5_C PF11792.8 KFM27497.1 - 0.00076 19.1 0.8 0.0015 18.2 0.8 1.5 1 1 0 1 1 1 1 Baculoviridae late expression factor 5 C-terminal domain zinc_ribbon_10 PF10058.9 KFM27497.1 - 0.011 15.4 0.3 0.021 14.5 0.3 1.4 1 1 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-ribbon_3 PF13248.6 KFM27497.1 - 0.033 13.6 1.3 0.46 10.0 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Pkinase PF00069.25 KFM27498.1 - 2.3e-58 197.6 0.0 3e-58 197.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM27498.1 - 4.6e-28 98.2 0.0 6.2e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFM27498.1 - 8.1e-08 32.5 3.3 0.00074 19.5 0.2 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KFM27498.1 - 5.4e-07 29.2 0.0 7.5e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFM27498.1 - 0.0014 18.0 0.3 0.0021 17.4 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFM27498.1 - 0.031 13.2 0.0 0.043 12.8 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain TauD PF02668.16 KFM27499.1 - 4.8e-28 98.7 0.0 7.9e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KFM27499.1 - 0.022 13.9 0.0 0.034 13.3 0.0 1.2 1 0 0 1 1 1 0 CsiD MAGI_u5 PF16666.5 KFM27499.1 - 0.1 12.8 0.5 8.7 6.5 0.0 2.4 2 0 0 2 2 2 0 Unstructured region on MAGI TilS PF09179.11 KFM27499.1 - 0.8 10.2 6.1 1.8 9.1 0.4 3.7 3 0 0 3 3 3 0 TilS substrate binding domain Vps52 PF04129.12 KFM27500.1 - 1.2e-94 317.9 0.0 2.5e-92 310.3 0.0 2.1 1 1 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 KFM27500.1 - 3.6e-10 38.9 0.0 4.8e-08 31.9 0.2 2.2 2 0 0 2 2 2 2 Exocyst complex component Sec3 Cep57_MT_bd PF06657.13 KFM27500.1 - 0.033 14.6 0.1 0.13 12.7 0.0 2.1 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 FapA PF03961.13 KFM27500.1 - 0.093 11.3 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A V-SNARE PF05008.15 KFM27500.1 - 0.093 13.1 1.5 5.8 7.4 0.1 3.0 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus CENP-F_leu_zip PF10473.9 KFM27500.1 - 0.11 12.5 0.3 0.25 11.4 0.3 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sec34 PF04136.15 KFM27500.1 - 0.13 12.1 0.2 0.28 11.0 0.2 1.5 1 0 0 1 1 1 0 Sec34-like family EzrA PF06160.12 KFM27500.1 - 0.13 10.4 0.7 0.19 9.8 0.7 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Spc7 PF08317.11 KFM27500.1 - 0.22 10.3 1.3 0.41 9.5 1.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1455 PF07306.11 KFM27500.1 - 9 6.3 11.1 7.1 6.6 8.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1455) SLD5_C PF16922.5 KFM27501.1 - 9.3e-15 54.6 0.2 2.9e-14 53.0 0.0 1.9 2 0 0 2 2 2 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 KFM27501.1 - 0.00013 22.4 1.0 0.00026 21.4 0.9 1.6 1 1 0 1 1 1 1 GINS complex protein PDH PF02153.17 KFM27502.1 - 2.8e-20 72.4 0.0 3.7e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 KFM27502.1 - 4.4e-10 40.0 0.0 8.7e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KFM27502.1 - 1.4e-06 28.6 0.0 2.3e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KFM27502.1 - 3.4e-06 26.5 0.0 5.1e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 KFM27502.1 - 0.0023 17.6 0.1 0.0039 16.8 0.1 1.5 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Rossmann-like PF10727.9 KFM27502.1 - 0.02 14.7 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 Rossmann-like domain 3HCDH_N PF02737.18 KFM27502.1 - 0.04 13.8 0.3 0.12 12.3 0.1 1.9 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KFM27502.1 - 0.17 11.9 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.18 KFM27502.1 - 0.19 12.0 0.0 0.34 11.2 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain RNA_pol_Rpb8 PF03870.15 KFM27503.1 - 4.5e-49 166.2 0.0 5e-49 166.1 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 MFS_1_like PF12832.7 KFM27504.1 - 1.8e-46 158.8 0.0 1e-39 136.5 0.2 2.1 2 0 0 2 2 2 2 MFS_1 like family Nuc_H_symport PF03825.16 KFM27504.1 - 0.064 12.2 4.8 0.096 11.7 4.8 1.2 1 0 0 1 1 1 0 Nucleoside H+ symporter Gemini_mov PF01708.16 KFM27505.1 - 0.068 12.9 0.1 0.089 12.6 0.1 1.2 1 0 0 1 1 1 0 Geminivirus putative movement protein Tau95 PF09734.9 KFM27506.1 - 2.9e-19 70.3 0.0 4.4e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain DUF3104 PF11302.8 KFM27506.1 - 0.058 13.1 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) ABC1 PF03109.16 KFM27507.1 - 3.3e-35 120.8 0.0 6.5e-35 119.9 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 KFM27507.1 - 0.00034 20.6 4.0 0.00065 19.7 0.1 2.6 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 KFM27507.1 - 0.063 12.6 0.0 0.2 11.0 0.0 1.7 2 0 0 2 2 2 0 Protein kinase domain adh_short PF00106.25 KFM27508.1 - 3.6e-23 82.1 0.3 2.7e-16 59.6 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFM27508.1 - 2.8e-14 53.2 0.1 8.8e-13 48.4 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Bromodomain PF00439.25 KFM27509.1 - 3.4e-18 65.5 0.0 6.5e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 KFM27509.1 - 6.3e-14 51.9 0.0 1.4e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation ABC2_membrane PF01061.24 KFM27509.1 - 6e-10 38.9 7.9 6e-10 38.9 7.9 1.7 2 0 0 2 2 2 1 ABC-2 type transporter PDR_assoc PF08370.11 KFM27509.1 - 1.6e-07 31.0 0.0 2.7e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Plant PDR ABC transporter associated ABC2_membrane_3 PF12698.7 KFM27509.1 - 2.4 7.2 8.9 3.3 6.7 8.9 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF5325 PF17259.2 KFM27509.1 - 6 6.8 6.0 6 6.8 0.3 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5325) RANK_CRD_2 PF18278.1 KFM27511.1 - 0.035 14.2 0.1 0.067 13.3 0.1 1.4 1 0 0 1 1 1 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 Pectate_lyase_3 PF12708.7 KFM27513.1 - 0.0045 16.9 1.9 0.073 12.9 0.2 2.6 2 1 1 3 3 3 2 Pectate lyase superfamily protein NFACT-C PF11923.8 KFM27516.1 - 1.3e-26 92.5 0.0 3.7e-26 91.1 0.0 1.8 1 0 0 1 1 1 1 NFACT protein C-terminal domain NFACT-R_1 PF05670.13 KFM27516.1 - 2.9e-25 89.0 0.0 6.4e-25 87.9 0.0 1.6 1 0 0 1 1 1 1 NFACT protein RNA binding domain FbpA PF05833.11 KFM27516.1 - 3.7e-18 65.5 0.1 3e-15 55.9 0.0 2.2 1 1 1 2 2 2 2 Fibronectin-binding protein A N-terminus (FbpA) DUF1421 PF07223.11 KFM27517.1 - 1.6e-14 53.5 0.6 1.6e-14 53.5 0.6 1.8 2 0 0 2 2 2 1 UBA-like domain (DUF1421) WIYLD PF10440.9 KFM27517.1 - 0.0049 16.6 0.0 0.03 14.1 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-binding WIYLD domain CorA PF01544.18 KFM27517.1 - 0.045 13.1 0.1 0.08 12.2 0.1 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein CdvA PF18822.1 KFM27517.1 - 0.056 13.3 0.1 0.14 12.0 0.1 1.7 1 1 0 1 1 1 0 CdvA-like coiled-coil domain IFT57 PF10498.9 KFM27517.1 - 0.064 12.2 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Baculo_PEP_C PF04513.12 KFM27517.1 - 0.077 13.0 0.0 0.62 10.1 0.0 2.1 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 KFM27517.1 - 1.3 8.8 6.9 3 7.7 6.9 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain CorA PF01544.18 KFM27518.1 - 8.2e-08 31.9 0.7 3.8e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein TLE_N PF03920.15 KFM27518.1 - 0.037 14.1 0.1 0.07 13.2 0.1 1.3 1 0 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain TolA_bind_tri PF16331.5 KFM27518.1 - 0.085 12.9 1.8 3.6 7.7 0.4 2.4 2 0 0 2 2 2 0 TolA binding protein trimerisation VIT1 PF01988.19 KFM27518.1 - 0.098 12.5 0.1 0.3 10.9 0.0 1.7 2 0 0 2 2 2 0 VIT family Baculo_PEP_C PF04513.12 KFM27518.1 - 0.14 12.2 0.3 0.29 11.2 0.3 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus HalX PF08663.10 KFM27518.1 - 0.18 12.1 5.7 0.32 11.3 1.6 2.6 2 0 0 2 2 2 0 HalX domain Apolipoprotein PF01442.18 KFM27518.1 - 0.46 10.3 6.4 0.18 11.6 3.9 1.5 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain CLZ PF16526.5 KFM27518.1 - 1 9.8 5.7 0.63 10.4 0.6 2.8 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Tektin PF03148.14 KFM27518.1 - 1.6 7.4 7.8 0.11 11.3 2.2 1.7 2 0 0 2 2 2 0 Tektin family LapA_dom PF06305.11 KFM27518.1 - 3.2 7.6 8.5 1.2 9.0 0.9 2.8 2 1 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Uds1 PF15456.6 KFM27518.1 - 3.3 7.9 5.5 5.8 7.1 1.0 2.4 2 1 0 2 2 2 0 Up-regulated During Septation Nop PF01798.18 KFM27519.1 - 7.8e-51 172.8 0.0 3.3e-47 160.9 0.0 2.2 1 1 1 2 2 2 2 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 KFM27519.1 - 7.7e-39 133.3 1.9 1.4e-38 132.5 1.9 1.4 1 0 0 1 1 1 1 Prp31 C terminal domain Metal_CEHH PF14455.6 KFM27519.1 - 0.17 11.5 0.1 0.28 10.8 0.1 1.3 1 0 0 1 1 1 0 Predicted metal binding domain TPT PF03151.16 KFM27520.1 - 2.6e-48 164.9 21.2 3.2e-48 164.6 21.2 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KFM27520.1 - 1.3e-08 34.4 20.2 1.7e-08 34.0 20.2 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KFM27520.1 - 2.9e-08 34.0 30.1 0.00055 20.1 11.9 2.3 2 0 0 2 2 2 2 EamA-like transporter family UTP25 PF06862.12 KFM27521.1 - 3.8e-133 444.7 0.0 4.8e-133 444.4 0.0 1.0 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 SDA1 PF05285.12 KFM27521.1 - 3.9 6.8 18.1 6.4 6.1 18.1 1.2 1 0 0 1 1 1 0 SDA1 RIBIOP_C PF04950.12 KFM27522.1 - 3.7e-64 217.0 0.1 2.4e-63 214.3 0.0 2.0 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KFM27522.1 - 2.7e-20 72.2 0.0 6e-20 71.1 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 KFM27522.1 - 0.018 14.6 0.0 0.13 11.8 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Orthopox_F7 PF05813.12 KFM27522.1 - 0.12 12.6 0.1 0.3 11.2 0.1 1.6 1 0 0 1 1 1 0 Orthopoxvirus F7 protein Ribosomal_L18p PF00861.22 KFM27523.1 - 7.3e-18 65.0 0.2 8.6e-18 64.8 0.2 1.0 1 0 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast ING PF12998.7 KFM27524.1 - 7.8e-16 58.5 0.3 3e-15 56.7 0.3 1.7 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding BRE1 PF08647.11 KFM27524.1 - 0.0025 17.8 1.4 0.52 10.4 0.3 2.1 2 0 0 2 2 2 2 BRE1 E3 ubiquitin ligase DUF2968 PF11180.8 KFM27524.1 - 0.14 11.8 7.2 0.88 9.2 1.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) RRM_2 PF04059.12 KFM27525.1 - 6.2e-34 116.1 0.0 8.5e-34 115.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif 2 Smg4_UPF3 PF03467.15 KFM27525.1 - 0.039 14.0 0.0 0.062 13.3 0.0 1.2 1 0 0 1 1 1 0 Smg-4/UPF3 family RRM_1 PF00076.22 KFM27525.1 - 0.044 13.6 0.0 0.083 12.7 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 2Fe-2S_thioredx PF01257.19 KFM27525.1 - 0.15 11.9 0.1 0.22 11.3 0.1 1.2 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin CLPTM1 PF05602.12 KFM27526.1 - 3.3e-111 372.4 1.9 5.4e-110 368.4 1.9 2.2 1 1 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 KFM27526.1 - 4.1e-05 23.3 0.4 0.023 14.4 0.0 2.5 2 0 0 2 2 2 2 PQ loop repeat Hpre_diP_synt_I PF07456.11 KFM27526.1 - 0.58 10.2 3.1 2.1 8.4 1.0 2.2 2 0 0 2 2 2 0 Heptaprenyl diphosphate synthase component I RPAP1_N PF08621.10 KFM27527.1 - 8.5e-08 31.8 1.1 1.9e-07 30.7 1.1 1.6 1 0 0 1 1 1 1 RPAP1-like, N-terminal RPAP1_C PF08620.10 KFM27527.1 - 3.7e-07 30.2 0.0 1.5e-06 28.2 0.0 2.1 2 0 0 2 2 2 1 RPAP1-like, C-terminal Lipase_3 PF01764.25 KFM27528.1 - 3.7e-20 72.2 0.0 5.9e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 KFM27528.1 - 0.028 13.7 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 YccV-like PF08755.11 KFM27529.1 - 2.3e-26 92.2 0.0 3.2e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like UbiA PF01040.18 KFM27531.1 - 1.7e-23 83.2 15.6 2.2e-23 82.9 15.6 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF1722 PF08349.11 KFM27532.1 - 0.091 13.1 0.1 0.18 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) Ribonuc_red_lgN PF00317.21 KFM27532.1 - 0.14 12.1 0.1 0.27 11.3 0.1 1.4 1 0 0 1 1 1 0 Ribonucleotide reductase, all-alpha domain Pkinase PF00069.25 KFM27534.1 - 2.7e-09 36.8 0.0 4.5e-08 32.8 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KFM27534.1 - 0.00017 21.0 0.0 0.00024 20.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KFM27534.1 - 0.049 12.9 0.1 0.31 10.3 0.1 2.0 1 1 0 1 1 1 0 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFM27534.1 - 0.32 9.7 0.0 0.43 9.3 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pkinase_Tyr PF07714.17 KFM27536.1 - 1.4e-05 24.5 0.0 2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM27536.1 - 0.023 14.1 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain PsaD PF02531.16 KFM27539.1 - 2.9e-67 224.4 0.1 4.6e-67 223.7 0.0 1.3 2 0 0 2 2 2 1 PsaD AAA PF00004.29 KFM27540.1 - 5.2e-40 136.9 0.0 8.3e-40 136.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.18 KFM27540.1 - 1.1e-20 73.4 3.2 2.9e-20 72.1 3.2 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Vps4_C PF09336.10 KFM27540.1 - 3.6e-20 71.7 0.0 1.2e-19 70.1 0.0 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 KFM27540.1 - 2.3e-06 27.4 0.0 3.9e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KFM27540.1 - 1.6e-05 25.3 0.1 0.0021 18.5 0.0 2.9 1 1 0 2 2 2 1 AAA ATPase domain AAA_lid_3 PF17862.1 KFM27540.1 - 9.7e-05 22.1 0.0 0.00046 19.9 0.0 2.2 2 0 0 2 2 1 1 AAA+ lid domain IstB_IS21 PF01695.17 KFM27540.1 - 0.00011 22.0 0.0 0.00022 21.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 KFM27540.1 - 0.00014 22.2 0.1 0.014 15.7 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 KFM27540.1 - 0.00015 21.8 0.0 0.001 19.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 KFM27540.1 - 0.00018 20.8 0.0 0.00034 19.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.14 KFM27540.1 - 0.00081 19.5 0.0 0.0014 18.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 KFM27540.1 - 0.0014 18.7 0.0 0.0043 17.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain TIP49 PF06068.13 KFM27540.1 - 0.0018 17.5 0.0 0.0033 16.7 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain RNA_helicase PF00910.22 KFM27540.1 - 0.0021 18.4 0.0 0.02 15.2 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 KFM27540.1 - 0.0034 17.5 0.0 0.0068 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFM27540.1 - 0.004 17.7 0.0 0.0091 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KFM27540.1 - 0.0071 16.1 0.8 0.019 14.7 0.1 2.1 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KFM27540.1 - 0.037 14.4 0.0 0.11 13.0 0.0 1.8 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 KFM27540.1 - 0.041 13.3 0.0 0.095 12.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KFM27540.1 - 0.052 13.5 0.0 0.85 9.5 0.0 2.3 1 1 1 2 2 2 0 NACHT domain Parvo_NS1 PF01057.17 KFM27540.1 - 0.066 12.3 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ATPase PF06745.13 KFM27540.1 - 0.066 12.5 0.3 9.2 5.5 0.0 3.2 3 1 1 4 4 4 0 KaiC AAA_25 PF13481.6 KFM27540.1 - 0.09 12.3 0.1 0.78 9.3 0.1 2.2 1 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KFM27540.1 - 0.1 12.1 0.0 0.3 10.6 0.0 1.8 1 0 0 1 1 1 0 P-loop containing dynein motor region Torsin PF06309.11 KFM27540.1 - 0.1 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Torsin PhoH PF02562.16 KFM27540.1 - 0.12 11.8 0.1 0.24 10.8 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.26 KFM27540.1 - 0.14 11.9 0.0 0.45 10.2 0.0 1.8 1 1 1 2 2 2 0 Sigma-54 interaction domain ATPase_2 PF01637.18 KFM27540.1 - 0.15 11.9 0.0 1.7 8.5 0.0 2.4 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea CPT PF07931.12 KFM27540.1 - 0.15 11.9 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein USP8_dimer PF08969.11 KFM27540.1 - 1 9.6 3.4 2.6 8.2 1.4 2.5 3 0 0 3 3 2 0 USP8 dimerisation domain PFU PF09070.11 KFM27541.1 - 2.1e-32 111.7 0.0 4e-32 110.8 0.0 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 KFM27541.1 - 7.5e-24 83.6 21.0 0.001 19.9 0.0 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat PUL PF08324.11 KFM27541.1 - 1.4e-17 63.8 2.1 2.3e-11 43.5 0.7 2.1 1 1 1 2 2 2 2 PUL domain Ribonuc_L-PSP PF01042.21 KFM27542.1 - 2.3e-17 63.1 1.4 1e-07 32.0 0.1 2.1 1 1 1 2 2 2 2 Endoribonuclease L-PSP HEAT_EZ PF13513.6 KFM27543.1 - 6e-15 55.4 25.2 1.6e-08 34.8 0.0 8.4 8 1 1 9 9 9 4 HEAT-like repeat HEAT PF02985.22 KFM27543.1 - 9.4e-11 41.0 4.6 0.21 11.9 0.0 8.1 8 0 0 8 8 8 3 HEAT repeat IBN_N PF03810.19 KFM27543.1 - 3.3e-10 39.7 0.0 3e-09 36.6 0.0 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 KFM27543.1 - 0.00014 22.2 9.6 0.12 12.8 0.1 6.0 3 2 3 6 6 6 4 HEAT repeats Arm PF00514.23 KFM27543.1 - 0.0065 16.5 3.1 3.4 7.8 0.0 4.4 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat IFRD PF05004.13 KFM27543.1 - 0.0086 15.2 0.0 4.7 6.2 0.0 3.3 1 1 0 2 2 2 2 Interferon-related developmental regulator (IFRD) OPT PF03169.15 KFM27543.1 - 0.098 11.3 0.2 0.14 10.8 0.2 1.2 1 0 0 1 1 1 0 OPT oligopeptide transporter protein Nucleotid_trans PF03407.16 KFM27545.1 - 5.6e-06 26.5 0.0 9.1e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Mannosyl_trans3 PF11051.8 KFM27545.1 - 0.25 10.6 0.0 0.41 10.0 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative Nucleotid_trans PF03407.16 KFM27546.1 - 1.4e-10 41.5 0.0 2.7e-10 40.6 0.0 1.5 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Aa_trans PF01490.18 KFM27547.1 - 1.6e-38 132.5 18.7 2e-38 132.2 18.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein GPCR_chapero_1 PF11904.8 KFM27548.1 - 4.7e-30 105.1 0.0 6.3e-29 101.4 0.0 2.1 1 1 0 1 1 1 1 GPCR-chaperone zf-CCCH PF00642.24 KFM27548.1 - 6e-10 38.8 5.2 6e-10 38.8 5.2 1.7 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFM27548.1 - 7.7e-06 25.8 4.1 1.5e-05 24.9 4.1 1.5 1 0 0 1 1 1 1 Zinc finger domain Ank_2 PF12796.7 KFM27548.1 - 1.4e-05 25.6 0.1 2.7e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) zf-CCCH_4 PF18044.1 KFM27548.1 - 4.9e-05 23.0 4.2 9.1e-05 22.2 4.2 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger Ank_3 PF13606.6 KFM27548.1 - 0.00017 21.8 0.2 0.0096 16.4 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 KFM27548.1 - 0.00055 20.2 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFM27548.1 - 0.0014 19.2 0.1 0.0031 18.1 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KFM27548.1 - 0.0016 18.8 0.0 0.0055 17.1 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeat Torus PF16131.5 KFM27548.1 - 0.015 16.0 0.3 0.051 14.3 0.3 1.8 2 0 0 2 2 1 0 Torus domain zf-CCCH_2 PF14608.6 KFM27548.1 - 0.15 12.5 2.0 0.28 11.7 2.0 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger PilX_N PF14341.6 KFM27550.1 - 0.31 11.0 1.8 0.55 10.2 1.8 1.4 1 0 0 1 1 1 0 PilX N-terminal Ribosomal_L30 PF00327.20 KFM27551.1 - 1.7e-10 40.6 0.4 2.3e-10 40.2 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e RNA_pol_Rpb4 PF03874.16 KFM27552.1 - 3.9e-12 46.6 0.5 5.6e-12 46.1 0.5 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 DUF2388 PF09498.10 KFM27552.1 - 0.14 12.2 0.5 9 6.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2388) Peptidase_M20 PF01546.28 KFM27553.1 - 8.2e-30 104.1 0.2 1.3e-29 103.4 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Exo_endo_phos PF03372.23 KFM27553.1 - 5.5e-18 65.3 0.0 1.2e-17 64.2 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family M20_dimer PF07687.14 KFM27553.1 - 1.9e-17 63.2 0.0 4.4e-17 62.0 0.0 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain PDDEXK_6 PF04720.12 KFM27554.1 - 1.4e-17 64.4 0.0 2.3e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 PDDEXK-like family of unknown function Metallophos PF00149.28 KFM27556.1 - 5.6e-08 33.5 0.0 8.9e-08 32.9 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase UPF0565 PF10561.9 KFM27557.1 - 1e-10 41.3 0.0 1.1e-06 28.1 0.0 2.5 2 1 0 2 2 2 2 Uncharacterised protein family UPF0565 p450 PF00067.22 KFM27558.1 - 2e-46 158.7 0.0 2.8e-25 89.0 0.1 2.0 2 0 0 2 2 2 2 Cytochrome P450 TRAPP PF04051.16 KFM27559.1 - 7.7e-42 142.5 0.0 8.9e-42 142.3 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Ribosomal_L23eN PF03939.13 KFM27560.1 - 5.4e-14 52.1 10.2 5.4e-14 52.1 10.2 2.2 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 KFM27560.1 - 1.5e-12 47.7 0.4 1.5e-12 47.7 0.4 2.0 2 1 0 2 2 2 1 Ribosomal protein L23 CENP-T_C PF15511.6 KFM27561.1 - 1.6e-07 31.4 0.0 2.7e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KFM27561.1 - 0.00013 22.3 0.0 0.00028 21.2 0.0 1.5 1 0 0 1 1 1 1 CENP-S protein PI3_PI4_kinase PF00454.27 KFM27562.1 - 0.0067 16.3 0.0 0.0094 15.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase ARL17 PF15840.5 KFM27562.1 - 0.043 14.2 0.4 0.043 14.2 0.4 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor-like protein 17 CPSase_L_D2 PF02786.17 KFM27563.1 - 3.4e-103 343.7 0.1 9.5e-67 224.6 0.3 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 KFM27563.1 - 4.5e-39 133.6 0.0 8.9e-39 132.6 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain MGS PF02142.22 KFM27563.1 - 9.5e-17 61.0 0.0 2.8e-16 59.5 0.0 1.9 1 0 0 1 1 1 1 MGS-like domain ATP-grasp PF02222.22 KFM27563.1 - 2.3e-12 46.8 0.0 1.2e-09 38.0 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_4 PF13535.6 KFM27563.1 - 9.3e-10 38.3 0.0 4e-05 23.3 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KFM27563.1 - 5.7e-08 32.5 0.0 1.7e-06 27.7 0.0 2.3 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 KFM27563.1 - 5.8e-08 32.6 0.1 0.011 15.5 0.0 3.1 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 KFM27563.1 - 2e-05 24.7 0.0 0.006 16.6 0.0 2.6 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_2 PF08442.10 KFM27563.1 - 7e-05 22.5 0.0 0.076 12.6 0.0 2.9 2 1 0 2 2 2 2 ATP-grasp domain RimK PF08443.11 KFM27563.1 - 0.00032 20.3 0.0 0.45 10.1 0.0 2.7 3 0 0 3 3 3 2 RimK-like ATP-grasp domain GARS_A PF01071.19 KFM27563.1 - 0.0014 18.5 0.1 0.3 10.8 0.2 2.4 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.6 KFM27563.1 - 0.027 13.9 0.0 0.83 9.1 0.0 2.5 2 0 0 2 2 2 0 ATP-grasp domain TP_methylase PF00590.20 KFM27564.1 - 0.021 14.8 0.0 0.042 13.8 0.0 1.5 1 1 0 1 1 1 0 Tetrapyrrole (Corrin/Porphyrin) Methylases Slu7 PF11708.8 KFM27565.1 - 6.5e-81 272.0 2.6 6.5e-81 272.0 2.6 1.9 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor ANAPC4_WD40 PF12894.7 KFM27566.1 - 2.4e-14 53.4 0.1 2e-05 24.8 0.0 6.3 2 2 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFM27566.1 - 7.4e-10 39.3 12.3 0.031 15.2 0.0 8.1 7 1 1 8 8 8 2 WD domain, G-beta repeat IKI3 PF04762.12 KFM27566.1 - 1.5e-05 23.3 0.1 0.055 11.5 0.0 4.2 4 1 1 5 5 5 2 IKI3 family PD40 PF07676.12 KFM27566.1 - 0.0001 22.1 2.6 9 6.4 0.0 5.6 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KFM27566.1 - 0.00016 21.6 0.0 15 5.4 0.0 5.1 3 2 2 5 5 5 1 Eukaryotic translation initiation factor eIF2A SGL PF08450.12 KFM27566.1 - 0.089 12.4 0.0 1.2 8.7 0.0 2.6 3 1 0 4 4 4 0 SMP-30/Gluconolactonase/LRE-like region AP2 PF00847.20 KFM27567.1 - 1.1e-05 25.6 0.2 2.8e-05 24.3 0.2 1.8 1 0 0 1 1 1 1 AP2 domain Ank_4 PF13637.6 KFM27568.1 - 7.7e-13 48.7 7.4 3.8e-05 24.2 0.3 4.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM27568.1 - 8.9e-12 45.4 0.6 4.7e-05 23.9 0.2 3.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFM27568.1 - 5.5e-08 32.9 5.3 0.0007 19.8 0.2 3.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM27568.1 - 1.9e-07 30.8 8.7 0.37 11.5 0.2 5.3 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 KFM27568.1 - 4.6e-05 23.7 10.4 0.69 10.5 0.1 4.7 4 0 0 4 4 4 2 Ankyrin repeat zf-C3HC4_3 PF13920.6 KFM27569.1 - 2.3e-10 40.2 3.5 2.9e-10 39.9 3.5 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM27569.1 - 3.2e-06 26.9 5.0 4.2e-06 26.5 5.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM27569.1 - 9.6e-06 25.8 6.0 1.3e-05 25.5 6.0 1.2 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KFM27569.1 - 7.6e-05 22.5 4.8 0.00012 21.9 4.8 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KFM27569.1 - 0.00012 21.8 6.1 0.00018 21.3 6.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM27569.1 - 0.0006 19.7 4.3 0.00095 19.1 4.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFM27569.1 - 0.00066 19.7 2.8 0.0017 18.3 2.8 1.8 1 1 0 1 1 1 1 RING-type zinc-finger Baculo_IE-1 PF05290.11 KFM27569.1 - 0.021 14.8 0.3 0.028 14.4 0.3 1.1 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.6 KFM27569.1 - 0.078 12.8 2.0 0.15 11.9 2.0 1.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KFM27569.1 - 1.6 8.9 6.2 3 8.1 6.2 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING APG9 PF04109.16 KFM27570.1 - 1.8e-164 548.3 8.1 2.1e-164 548.1 8.1 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 ABM PF03992.16 KFM27570.1 - 4.5e-05 23.5 0.0 9.4e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase WD40 PF00400.32 KFM27571.1 - 5.2e-29 99.9 19.7 1.3e-06 29.0 0.2 7.5 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM27571.1 - 1.4e-06 28.5 0.6 6.1 7.2 0.0 4.4 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFM27571.1 - 0.0005 20.0 0.2 0.088 12.7 0.0 2.7 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KFM27571.1 - 0.0072 14.9 0.1 0.48 8.9 0.0 2.4 2 0 0 2 2 2 2 Cytochrome D1 heme domain TauD PF02668.16 KFM27572.1 - 7.7e-19 68.5 0.1 2.1e-18 67.1 0.1 1.6 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family AAA PF00004.29 KFM27573.1 - 7.3e-45 152.6 0.0 6.2e-40 136.7 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFM27573.1 - 1.2e-10 41.0 3.7 2.6e-10 39.9 0.2 2.7 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 KFM27573.1 - 4.7e-07 30.3 0.2 4.7e-07 30.3 0.2 3.6 3 2 0 3 3 3 1 AAA ATPase domain Bromodomain PF00439.25 KFM27573.1 - 3.7e-06 26.9 0.0 9.6e-06 25.6 0.0 1.6 2 0 0 2 2 1 1 Bromodomain AAA_2 PF07724.14 KFM27573.1 - 6.8e-06 26.3 0.0 1.2e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KFM27573.1 - 1.3e-05 25.0 0.0 4.1e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_5 PF07728.14 KFM27573.1 - 0.00013 21.9 0.0 0.00031 20.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KFM27573.1 - 0.00042 20.6 1.3 0.021 15.1 0.3 3.2 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KFM27573.1 - 0.00073 19.7 0.1 0.013 15.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KFM27573.1 - 0.0019 18.8 0.0 0.019 15.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFM27573.1 - 0.0042 16.8 1.2 0.0063 16.3 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KFM27573.1 - 0.0055 17.0 0.4 0.054 13.7 0.0 2.9 3 1 0 3 3 3 1 AAA domain ResIII PF04851.15 KFM27573.1 - 0.0075 16.3 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 KFM27573.1 - 0.011 16.1 0.0 0.039 14.4 0.0 1.9 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.21 KFM27573.1 - 0.013 14.8 0.3 0.087 12.2 0.1 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KFM27573.1 - 0.014 15.0 0.3 0.05 13.2 0.3 1.9 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KFM27573.1 - 0.027 14.4 0.0 0.084 12.8 0.0 1.9 2 0 0 2 2 1 0 NACHT domain AAA_14 PF13173.6 KFM27573.1 - 0.032 14.3 0.0 0.054 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AFG1_ATPase PF03969.16 KFM27573.1 - 0.039 12.8 0.0 0.093 11.6 0.0 1.6 2 0 0 2 2 2 0 AFG1-like ATPase AAA_11 PF13086.6 KFM27573.1 - 0.045 13.5 0.0 0.087 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KFM27573.1 - 0.05 13.3 0.1 0.17 11.6 0.0 2.0 2 1 0 2 2 1 0 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KFM27573.1 - 0.05 12.8 0.0 0.076 12.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain DUF2075 PF09848.9 KFM27573.1 - 0.098 11.9 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.6 KFM27573.1 - 0.11 12.6 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activat PF00158.26 KFM27573.1 - 0.12 12.1 0.0 0.41 10.3 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 KFM27573.1 - 0.22 10.6 0.0 3 6.9 0.0 2.2 3 0 0 3 3 2 0 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 KFM27573.1 - 0.24 10.9 0.0 0.45 10.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Pentapeptide_2 PF01469.18 KFM27574.1 - 1.5e-12 47.1 63.2 5.2e-07 29.4 28.8 2.2 2 0 0 2 2 2 2 Pentapeptide repeats (8 copies) SdrD_B PF17210.3 KFM27575.1 - 0.00023 21.3 0.0 0.0004 20.6 0.0 1.3 1 0 0 1 1 1 1 SdrD B-like domain CarboxypepD_reg PF13620.6 KFM27575.1 - 0.0047 17.2 0.1 0.024 14.9 0.0 2.2 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain Cse1 PF08506.10 KFM27576.1 - 3.5e-09 36.0 0.0 4.2e-05 22.5 0.0 2.3 2 0 0 2 2 2 2 Cse1 MFS_1 PF07690.16 KFM27577.1 - 0.00011 21.2 4.9 0.078 11.9 0.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DHHC PF01529.20 KFM27577.1 - 0.0013 18.9 0.9 0.022 14.9 0.2 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF981 PF06168.11 KFM27577.1 - 0.0029 17.6 1.2 0.28 11.1 0.4 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF981) CRCB PF02537.15 KFM27577.1 - 0.023 15.0 0.6 0.046 14.0 0.6 1.5 1 0 0 1 1 1 0 CrcB-like protein, Camphor Resistance (CrcB) Trp_oprn_chp PF09534.10 KFM27577.1 - 0.13 12.1 4.3 0.23 11.3 4.3 1.3 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) MFS_1 PF07690.16 KFM27578.1 - 4.8e-54 183.6 34.6 4.8e-54 183.6 34.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Nucleotid_trans PF03407.16 KFM27579.1 - 1.3e-30 107.0 0.0 1.8e-30 106.5 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DnaJ PF00226.31 KFM27581.1 - 4.1e-06 26.8 0.1 7.1e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain PI3K_P85_iSH2 PF16454.5 KFM27581.1 - 0.099 12.2 0.9 0.14 11.7 0.9 1.1 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain AAA_13 PF13166.6 KFM27581.1 - 0.1 11.3 1.1 0.14 10.8 1.1 1.0 1 0 0 1 1 1 0 AAA domain BRE1 PF08647.11 KFM27581.1 - 0.2 11.7 0.6 0.3 11.2 0.6 1.2 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase GAS PF13851.6 KFM27581.1 - 0.21 10.9 1.4 0.29 10.5 1.4 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 KFM27581.1 - 0.27 11.4 9.1 0.036 14.3 4.3 1.9 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Lebercilin PF15619.6 KFM27581.1 - 0.53 9.9 6.2 0.76 9.4 6.2 1.1 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF220 PF02713.14 KFM27582.1 - 0.0046 17.0 0.0 0.0078 16.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF220 Polyketide_cyc PF03364.20 KFM27582.1 - 0.0062 16.7 0.0 0.0082 16.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport PUB PF09409.10 KFM27583.1 - 4.1e-13 49.1 0.0 6.3e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 PUB domain UBX PF00789.20 KFM27583.1 - 0.00043 20.4 0.0 0.00067 19.8 0.0 1.2 1 0 0 1 1 1 1 UBX domain Xpo1 PF08389.12 KFM27585.1 - 4.1e-05 23.7 0.0 0.43 10.6 0.0 2.4 2 0 0 2 2 2 2 Exportin 1-like protein IglC PF11550.8 KFM27585.1 - 0.036 13.5 0.0 6.4 6.2 0.0 2.3 2 0 0 2 2 2 0 Intracellular growth locus C protein DUF4202 PF13875.6 KFM27585.1 - 0.13 12.2 0.2 20 5.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4202) Sec1 PF00995.23 KFM27590.1 - 1.6e-94 318.2 0.0 1.9e-94 318.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family PEP-utilisers_N PF05524.13 KFM27590.1 - 0.083 13.1 2.7 5.4 7.2 0.1 3.1 3 0 0 3 3 3 0 PEP-utilising enzyme, N-terminal YIF1 PF03878.15 KFM27592.1 - 1e-54 185.6 0.0 1.1e-54 185.5 0.0 1.0 1 0 0 1 1 1 1 YIF1 AAA_18 PF13238.6 KFM27593.1 - 6e-29 101.2 0.0 7.7e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KFM27593.1 - 3.2e-06 27.6 0.3 2.5e-05 24.7 0.2 2.2 1 1 1 2 2 2 1 AAA domain AAA PF00004.29 KFM27593.1 - 5.9e-05 23.5 0.0 9.8e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KFM27593.1 - 0.00032 20.9 0.7 0.036 14.2 0.4 2.4 1 1 1 2 2 2 1 AAA domain ADK PF00406.22 KFM27593.1 - 0.00045 20.4 0.2 0.012 15.7 0.0 2.2 2 0 0 2 2 2 1 Adenylate kinase NTPase_1 PF03266.15 KFM27593.1 - 0.0013 18.7 0.2 0.0053 16.7 0.0 2.0 2 0 0 2 2 2 1 NTPase AAA_28 PF13521.6 KFM27593.1 - 0.0018 18.6 2.9 0.0024 18.1 1.8 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFM27593.1 - 0.0039 17.6 0.0 0.0064 16.9 0.0 1.5 2 0 0 2 2 1 1 AAA ATPase domain AAA_24 PF13479.6 KFM27593.1 - 0.0087 15.8 0.0 0.029 14.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KFM27593.1 - 0.0094 16.0 0.2 0.025 14.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KFM27593.1 - 0.012 15.8 0.7 0.015 15.5 0.7 1.6 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 KFM27593.1 - 0.028 13.8 1.2 0.037 13.4 0.4 1.5 2 0 0 2 2 2 0 KaiC RuvB_N PF05496.12 KFM27593.1 - 0.03 14.1 0.1 0.059 13.1 0.0 1.6 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KFM27593.1 - 0.05 14.0 0.0 0.11 12.9 0.0 1.6 2 0 0 2 2 2 0 RNA helicase SKI PF01202.22 KFM27593.1 - 0.06 13.5 1.1 4.7 7.3 0.0 2.7 2 1 1 3 3 3 0 Shikimate kinase ResIII PF04851.15 KFM27593.1 - 0.072 13.1 0.0 0.1 12.6 0.0 1.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Zeta_toxin PF06414.12 KFM27593.1 - 0.088 12.1 0.5 0.18 11.1 0.1 1.6 2 0 0 2 2 2 0 Zeta toxin KTI12 PF08433.10 KFM27593.1 - 0.092 12.2 0.0 0.24 10.8 0.0 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 T2SSE PF00437.20 KFM27593.1 - 0.099 11.7 0.9 0.18 10.9 0.9 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 KFM27593.1 - 0.1 11.9 0.3 0.19 11.1 0.3 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 KFM27593.1 - 0.17 11.7 0.5 0.36 10.6 0.5 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mg_chelatase PF01078.21 KFM27593.1 - 0.17 11.2 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 KFM27593.1 - 0.17 12.4 0.5 0.3 11.6 0.5 1.7 1 1 0 1 1 1 0 ABC transporter AAA_19 PF13245.6 KFM27593.1 - 0.19 12.1 5.2 0.4 11.0 5.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KFM27593.1 - 0.62 9.8 4.0 0.85 9.3 2.5 1.8 1 1 1 2 2 2 0 AAA domain GcpE PF04551.14 KFM27595.1 - 7.2e-152 505.5 0.0 5e-151 502.7 0.0 2.0 1 1 0 1 1 1 1 GcpE protein PC_rep PF01851.22 KFM27595.1 - 9.2e-32 107.9 37.6 4e-06 27.0 0.2 9.4 10 0 0 10 10 10 8 Proteasome/cyclosome repeat RPN2_C PF18004.1 KFM27595.1 - 4.5e-28 98.2 2.0 1.3e-18 67.5 0.4 2.3 1 1 1 2 2 2 2 26S proteasome regulatory subunit RPN2 C-terminal domain HEAT_2 PF13646.6 KFM27595.1 - 2e-12 47.3 11.5 7.5e-10 39.1 0.1 5.6 4 1 2 6 6 6 2 HEAT repeats HEAT_EZ PF13513.6 KFM27595.1 - 2.5 8.7 9.6 5.8 7.5 0.3 5.4 3 1 1 4 4 4 0 HEAT-like repeat PsbP PF01789.16 KFM27596.1 - 2.9e-13 50.2 0.0 3.3e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 PsbP LCM PF04072.14 KFM27597.1 - 1e-26 94.0 0.0 2.4e-26 92.9 0.0 1.6 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase HLH PF00010.26 KFM27598.1 - 3.6e-09 36.5 0.5 6.1e-09 35.7 0.5 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Tom22 PF04281.13 KFM27598.1 - 0.025 14.4 0.1 0.025 14.4 0.1 1.6 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 MRI PF15325.6 KFM27598.1 - 0.57 11.3 9.7 2.5 9.2 1.3 3.1 2 1 0 2 2 2 0 Modulator of retrovirus infection S1 PF00575.23 KFM27600.1 - 0.00032 21.0 0.1 0.0057 17.0 0.0 2.5 2 1 0 2 2 2 1 S1 RNA binding domain KH_1 PF00013.29 KFM27601.1 - 5.1e-48 160.7 0.0 6.1e-10 38.8 0.0 5.1 4 1 1 5 5 5 5 KH domain KH_2 PF07650.17 KFM27601.1 - 3.9e-12 45.8 14.8 0.0012 18.6 0.4 5.2 3 2 2 5 5 5 5 KH domain KH_4 PF13083.6 KFM27601.1 - 9.5e-11 41.4 5.5 0.0046 16.8 0.0 5.1 4 1 1 5 5 5 3 KH domain KH_5 PF13184.6 KFM27601.1 - 1.8e-06 27.9 7.0 0.75 9.9 0.0 5.2 4 1 1 5 5 5 3 NusA-like KH domain DUF1418 PF07214.12 KFM27602.1 - 0.046 13.6 0.3 0.062 13.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) EMP70 PF02990.16 KFM27603.1 - 1.7e-215 716.6 40.3 1.3e-156 522.4 0.1 2.6 3 1 0 3 3 3 2 Endomembrane protein 70 Tom7 PF08038.12 KFM27603.1 - 0.057 13.1 4.0 5.9 6.6 0.3 2.8 2 0 0 2 2 2 0 TOM7 family EKLF_TAD1 PF16832.5 KFM27603.1 - 0.75 9.7 9.9 5.3 7.0 1.6 2.4 2 0 0 2 2 2 0 Erythroid krueppel-like transcription factor, transactivation 1 CLTH PF10607.9 KFM27605.1 - 1.9e-28 99.2 0.0 3.6e-28 98.3 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KFM27605.1 - 0.00062 19.6 0.0 0.0017 18.2 0.0 1.7 1 0 0 1 1 1 1 LisH zf-RING_UBOX PF13445.6 KFM27605.1 - 0.023 14.7 0.0 0.046 13.8 0.0 1.5 1 0 0 1 1 1 0 RING-type zinc-finger NikR_C PF08753.11 KFM27605.1 - 0.082 13.1 0.0 0.27 11.4 0.0 1.8 1 0 0 1 1 1 0 NikR C terminal nickel binding domain 4F5 PF04419.14 KFM27606.1 - 7.1e-07 30.0 16.8 8.4e-06 26.6 16.8 2.1 1 1 0 1 1 1 1 4F5 protein family Metallophos PF00149.28 KFM27607.1 - 3e-29 103.0 0.0 4.3e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 KFM27607.1 - 5.8e-23 81.0 0.0 1e-22 80.2 0.0 1.4 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_2 PF07719.17 KFM27607.1 - 5e-10 38.7 17.5 0.0001 22.1 1.2 3.8 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFM27607.1 - 6.5e-10 38.4 12.9 6.1e-05 22.7 0.9 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFM27607.1 - 2.9e-06 27.8 19.5 2.9e-05 24.6 7.7 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFM27607.1 - 4.7e-06 26.2 12.5 0.00093 18.8 0.7 2.8 2 1 1 3 3 3 2 TPR repeat TPR_17 PF13431.6 KFM27607.1 - 1.1e-05 25.5 4.2 0.064 13.7 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFM27607.1 - 0.0014 18.7 8.2 1.1 9.7 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFM27607.1 - 0.041 14.7 12.9 2.3 9.3 0.3 4.0 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 KFM27607.1 - 0.2 11.8 7.3 0.16 12.1 3.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFM27607.1 - 0.25 11.9 13.4 1.4 9.5 5.3 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF3856 PF12968.7 KFM27607.1 - 0.26 11.3 4.1 1.2 9.2 0.0 2.3 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) TPR_12 PF13424.6 KFM27607.1 - 0.36 11.2 10.3 5.9 7.3 2.3 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat UbiA PF01040.18 KFM27609.1 - 1e-98 329.7 37.9 6.7e-50 169.7 14.4 2.2 2 0 0 2 2 2 2 UbiA prenyltransferase family ERCC4 PF02732.15 KFM27610.1 - 1.8e-13 50.9 0.0 3.2e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 ERCC4 domain KfrA_N PF11740.8 KFM27610.1 - 0.13 12.9 5.9 0.62 10.8 1.3 3.5 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Vps39_2 PF10367.9 KFM27611.1 - 0.00037 20.9 0.0 0.00083 19.8 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Ras PF00071.22 KFM27612.1 - 7.1e-56 188.3 0.1 1.2e-55 187.6 0.1 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM27612.1 - 4.8e-32 110.7 0.0 9.1e-32 109.8 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM27612.1 - 6.4e-12 45.3 0.0 8.3e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFM27612.1 - 2.3e-07 30.9 0.0 4.6e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFM27612.1 - 1.7e-05 24.3 0.0 2.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFM27612.1 - 0.0001 21.9 0.0 0.0024 17.5 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain cobW PF02492.19 KFM27612.1 - 0.0016 18.1 0.0 0.0033 17.0 0.0 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 KFM27612.1 - 0.0022 18.0 0.0 0.0081 16.1 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KFM27612.1 - 0.0075 16.7 0.6 0.019 15.3 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain NTPase_1 PF03266.15 KFM27612.1 - 0.033 14.1 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.6 KFM27612.1 - 0.033 14.5 0.0 0.072 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 KFM27612.1 - 0.036 13.4 0.1 0.069 12.4 0.1 1.5 1 0 0 1 1 1 0 Septin MerE PF05052.12 KFM27612.1 - 0.036 14.0 0.0 0.067 13.1 0.0 1.5 1 0 0 1 1 1 0 MerE protein AAA_7 PF12775.7 KFM27612.1 - 0.037 13.5 0.0 0.06 12.9 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KFM27612.1 - 0.051 13.3 0.0 0.086 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 KFM27612.1 - 0.061 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 KFM27612.1 - 0.083 12.6 0.1 0.3 10.8 0.1 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATPase_2 PF01637.18 KFM27612.1 - 0.095 12.6 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TniB PF05621.11 KFM27612.1 - 0.15 11.4 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein MCM PF00493.23 KFM27612.1 - 0.16 11.1 0.1 0.23 10.5 0.1 1.2 1 0 0 1 1 1 0 MCM P-loop domain NB-ARC PF00931.22 KFM27612.1 - 0.16 11.1 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 KFM27612.1 - 0.16 11.8 0.1 0.35 10.8 0.1 1.5 1 0 0 1 1 1 0 NACHT domain BCAS2 PF05700.11 KFM27613.1 - 2.7e-59 200.4 6.8 3.3e-59 200.1 6.8 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Fmp27_WPPW PF10359.9 KFM27613.1 - 0.026 13.4 0.3 0.042 12.7 0.3 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain XkdW PF09636.10 KFM27613.1 - 0.14 12.3 1.8 0.27 11.4 0.3 2.1 1 1 2 3 3 3 0 XkdW protein BLOC1_2 PF10046.9 KFM27613.1 - 0.31 11.4 4.3 0.34 11.3 2.1 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CDPS PF16715.5 KFM27613.1 - 0.49 10.0 3.0 0.31 10.7 1.3 1.6 2 0 0 2 2 2 0 Cyclodipeptide synthase HALZ PF02183.18 KFM27613.1 - 0.8 10.0 4.9 3 8.2 0.3 3.2 2 1 1 3 3 3 0 Homeobox associated leucine zipper DivIC PF04977.15 KFM27613.1 - 1.6 8.6 6.8 3.5 7.5 0.1 2.9 2 1 1 3 3 3 0 Septum formation initiator APC_N_CC PF16689.5 KFM27613.1 - 2.1 8.5 5.9 0.59 10.2 1.2 2.4 2 1 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain ZapB PF06005.12 KFM27613.1 - 6.9 7.2 10.9 17 5.9 0.8 3.1 2 1 1 3 3 3 0 Cell division protein ZapB EF-hand_1 PF00036.32 KFM27614.1 - 1.5e-18 64.9 3.3 1.4e-06 27.4 0.1 3.4 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 KFM27614.1 - 1.4e-16 60.7 5.9 1e-11 45.1 0.2 3.0 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KFM27614.1 - 3.8e-15 54.5 2.8 0.0001 22.0 0.1 3.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 KFM27614.1 - 5.1e-10 38.4 7.2 0.00028 20.2 0.4 4.0 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 KFM27614.1 - 4.7e-07 29.6 9.2 2e-05 24.3 1.5 3.5 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 KFM27614.1 - 0.0065 16.4 0.3 0.49 10.4 0.1 2.3 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 KFM27614.1 - 0.019 15.2 1.1 0.91 9.8 0.7 2.6 2 1 0 2 2 2 0 Dockerin type I domain SPARC_Ca_bdg PF10591.9 KFM27614.1 - 0.035 14.4 0.7 18 5.7 0.1 3.3 1 1 2 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Tex_N PF09371.10 KFM27614.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Tex-like protein N-terminal domain EF-hand_9 PF14658.6 KFM27614.1 - 0.13 12.6 0.0 1.2 9.5 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain Mpv17_PMP22 PF04117.12 KFM27615.1 - 3.7e-14 52.7 0.1 5.8e-14 52.1 0.1 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family ubiquitin PF00240.23 KFM27616.1 - 6.1e-06 25.9 0.0 8e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Transcrip_reg PF01709.20 KFM27617.1 - 4.8e-67 225.9 0.0 5.3e-67 225.7 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator TPR_1 PF00515.28 KFM27619.1 - 0.01 15.6 3.4 7.8 6.5 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFM27619.1 - 0.93 9.8 8.9 27 5.2 1.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFM27619.1 - 4.3 7.7 15.9 7 7.0 1.0 4.2 3 1 0 3 3 3 0 Tetratricopeptide repeat CRAL_TRIO PF00650.20 KFM27620.1 - 1.9e-21 76.5 0.0 4.5e-21 75.2 0.0 1.6 1 1 1 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFM27620.1 - 0.0089 16.2 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain zf-TAZ PF02135.16 KFM27620.1 - 0.065 13.7 0.3 0.065 13.7 0.3 2.2 3 0 0 3 3 3 0 TAZ zinc finger RuBisCO_small PF00101.20 KFM27620.1 - 0.11 12.4 0.3 22 5.1 0.1 2.6 2 1 1 3 3 3 0 Ribulose bisphosphate carboxylase, small chain YjeF_N PF03853.15 KFM27622.1 - 2e-33 115.7 0.0 2.8e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus Putative_PNPOx PF01243.20 KFM27622.1 - 5.2e-20 71.4 0.0 9.4e-20 70.6 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 KFM27622.1 - 7.5e-18 64.3 2.6 1.5e-17 63.4 2.6 1.5 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.7 KFM27622.1 - 0.0049 17.5 0.0 0.0085 16.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Cpn10 PF00166.21 KFM27623.1 - 3.5e-52 174.4 2.4 6.5e-26 90.2 0.0 2.0 2 0 0 2 2 2 2 Chaperonin 10 Kd subunit Arf PF00025.21 KFM27624.1 - 4.1e-42 143.6 0.0 5.6e-27 94.3 0.0 2.4 1 1 1 2 2 2 2 ADP-ribosylation factor family SRPRB PF09439.10 KFM27624.1 - 0.00041 19.8 0.1 0.12 11.8 0.0 2.3 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KFM27624.1 - 0.006 15.8 0.3 3.1 6.9 0.0 2.6 2 1 0 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KFM27624.1 - 0.009 15.4 0.0 0.045 13.1 0.0 1.9 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Nup54 PF13874.6 KFM27624.1 - 0.025 14.7 2.5 0.045 13.8 2.5 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 GAT PF03127.14 KFM27624.1 - 0.058 13.7 0.4 0.13 12.6 0.4 1.5 1 0 0 1 1 1 0 GAT domain Roc PF08477.13 KFM27624.1 - 0.071 13.3 0.2 2.4 8.4 0.1 2.3 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase 6PF2K PF01591.18 KFM27624.1 - 0.14 11.5 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase MATH PF00917.26 KFM27625.1 - 7e-06 26.2 0.0 0.0037 17.4 0.0 3.1 3 0 0 3 3 3 2 MATH domain LRR_4 PF12799.7 KFM27626.1 - 2.6e-26 91.2 0.2 0.0009 19.6 0.0 6.3 3 1 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFM27626.1 - 6.1e-26 90.0 6.3 2.4e-07 30.4 0.0 5.4 5 1 0 5 5 5 4 Leucine rich repeat LRR_1 PF00560.33 KFM27626.1 - 4.3e-09 35.7 3.9 18 6.4 0.0 8.0 9 0 0 9 9 9 1 Leucine Rich Repeat LRR_9 PF14580.6 KFM27626.1 - 0.00048 19.7 0.1 0.19 11.2 0.0 3.0 1 1 3 4 4 4 1 Leucine-rich repeat Esterase PF00756.20 KFM27626.1 - 0.016 14.9 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Hydrolase_4 PF12146.8 KFM27626.1 - 0.071 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 LRR_6 PF13516.6 KFM27626.1 - 0.18 12.0 10.9 37 4.7 0.0 6.1 8 0 0 8 8 8 0 Leucine Rich repeat EMG1 PF03587.14 KFM27627.1 - 8.3e-69 231.1 0.0 9.5e-69 230.9 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Pribosyltran_N PF13793.6 KFM27630.1 - 8.2e-41 138.6 0.0 2.7e-40 136.9 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KFM27630.1 - 4.4e-25 88.8 0.4 1.8e-24 86.8 0.1 1.9 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KFM27630.1 - 3.9e-18 65.5 0.8 7.6e-18 64.5 0.8 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KFM27630.1 - 0.00087 18.8 0.1 0.0015 18.0 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 KFM27630.1 - 0.037 13.5 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase TPK_catalytic PF04263.16 KFM27631.1 - 3.7e-35 120.6 0.0 4.8e-35 120.2 0.0 1.1 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 KFM27631.1 - 0.00011 21.9 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain HAGH_C PF16123.5 KFM27632.1 - 1.3e-21 76.8 0.0 2.1e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 KFM27632.1 - 1.5e-19 70.8 2.4 1.3e-18 67.7 2.4 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KFM27632.1 - 0.02 14.4 0.3 0.053 13.0 0.2 1.7 1 1 1 2 2 2 0 Beta-lactamase superfamily domain Thiolase_N PF00108.23 KFM27633.1 - 2.3e-75 253.3 2.1 3.5e-75 252.7 2.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFM27633.1 - 1.6e-48 163.4 0.5 3.1e-48 162.5 0.5 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KFM27633.1 - 4.4e-05 23.2 0.8 4.4e-05 23.2 0.8 2.8 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KFM27633.1 - 0.086 12.7 4.6 0.92 9.4 0.2 3.5 3 1 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ribosomal_L9_C PF03948.14 KFM27634.1 - 1.4e-19 70.3 0.7 1.9e-19 69.9 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein L9, C-terminal domain Ribosomal_L9_N PF01281.19 KFM27634.1 - 3.3e-16 58.6 0.0 6.2e-16 57.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain HTH_33 PF13592.6 KFM27634.1 - 0.048 13.3 0.2 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn helix Peptidase_M41 PF01434.18 KFM27635.1 - 0.11 12.3 0.1 5.8 6.7 0.0 2.3 2 0 0 2 2 2 0 Peptidase family M41 MMR_HSR1_Xtn PF16897.5 KFM27636.1 - 2.6e-39 133.5 0.1 4.6e-39 132.7 0.1 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KFM27636.1 - 2e-20 73.0 0.0 3.9e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 KFM27636.1 - 2.7e-19 69.0 0.0 5e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 KFM27636.1 - 7.1e-11 41.9 0.0 1.3e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KFM27636.1 - 0.00031 20.9 0.1 0.36 10.9 0.0 2.4 1 1 1 2 2 2 2 Dynamin family AAA_28 PF13521.6 KFM27636.1 - 0.096 12.9 0.4 0.21 11.8 0.4 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KFM27636.1 - 0.15 11.9 0.0 2.5 8.0 0.0 2.5 3 0 0 3 3 3 0 RsgA GTPase 5_nucleotid_C PF02872.18 KFM27637.1 - 4e-40 137.6 0.0 6.6e-40 136.9 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KFM27637.1 - 0.02 15.4 0.1 0.049 14.1 0.1 1.7 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase Abhydrolase_6 PF12697.7 KFM27638.1 - 3.3e-14 54.0 5.9 5e-14 53.4 5.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFM27638.1 - 0.00013 21.7 0.4 0.00081 19.1 0.1 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFM27638.1 - 0.00022 20.6 0.0 0.00036 19.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KFM27638.1 - 0.03 14.4 0.0 0.058 13.5 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain AAA PF00004.29 KFM27640.1 - 5.4e-33 114.2 0.0 8.8e-33 113.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) GATA PF00320.27 KFM27640.1 - 1.7e-11 43.5 9.5 1.7e-11 43.5 9.5 2.0 2 0 0 2 2 2 1 GATA zinc finger AAA_5 PF07728.14 KFM27640.1 - 1.3e-07 31.7 0.0 3.2e-07 30.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KFM27640.1 - 5.1e-06 26.3 0.0 1.3e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KFM27640.1 - 0.00014 22.3 0.6 0.032 14.6 0.1 3.6 2 2 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KFM27640.1 - 0.0021 18.2 0.0 0.0051 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KFM27640.1 - 0.0041 17.4 0.1 0.012 15.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KFM27640.1 - 0.012 15.9 0.0 0.062 13.6 0.0 2.2 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 KFM27640.1 - 0.013 14.9 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.6 KFM27640.1 - 0.03 14.3 0.0 0.05 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KFM27640.1 - 0.037 14.6 0.0 0.081 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain OrfB_Zn_ribbon PF07282.11 KFM27640.1 - 3 7.8 10.7 0.12 12.4 0.2 2.4 2 0 0 2 2 2 0 Putative transposase DNA-binding domain ABC2_membrane PF01061.24 KFM27641.1 - 1.2e-29 103.3 24.3 1.9e-29 102.6 24.3 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ERp29 PF07749.12 KFM27641.1 - 1.6e-13 51.3 0.0 4e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain ABC_tran PF00005.27 KFM27641.1 - 3.1e-12 47.2 0.0 5.7e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KFM27641.1 - 0.00088 19.2 0.0 0.0014 18.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 KFM27641.1 - 0.11 11.6 20.9 0.17 11.0 20.9 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF5090 PF17009.5 KFM27641.1 - 1.7 8.5 7.9 3.9 7.4 7.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) WD40 PF00400.32 KFM27643.1 - 0.041 14.8 0.0 0.22 12.5 0.0 2.3 1 0 0 1 1 1 0 WD domain, G-beta repeat Methyltransf_15 PF09445.10 KFM27644.1 - 3.3e-31 108.1 0.0 4.4e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase DUF167 PF02594.16 KFM27644.1 - 2.8e-19 69.0 0.1 2.8e-19 69.0 0.1 1.7 2 0 0 2 2 2 1 Uncharacterised ACR, YggU family COG1872 Cons_hypoth95 PF03602.15 KFM27644.1 - 1.2e-06 28.3 0.0 2.1e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.16 KFM27644.1 - 2.5e-06 27.4 0.0 4.7e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein UPF0020 PF01170.18 KFM27644.1 - 0.014 15.1 0.0 0.046 13.4 0.0 1.8 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Methyltr_RsmB-F PF01189.17 KFM27644.1 - 0.053 13.2 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F MTS PF05175.14 KFM27644.1 - 0.054 13.0 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.12 KFM27644.1 - 0.06 14.0 0.0 0.14 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 KFM27644.1 - 0.21 11.5 0.0 0.34 10.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Ist1 PF03398.14 KFM27645.1 - 6.8e-44 149.7 0.2 9.5e-44 149.2 0.2 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway SLC35F PF06027.12 KFM27646.1 - 3e-08 33.5 3.2 3e-08 33.5 3.2 1.9 2 0 0 2 2 2 1 Solute carrier family 35 EamA PF00892.20 KFM27646.1 - 7.1e-08 32.7 41.7 1.7e-05 25.0 7.1 4.2 3 2 0 3 3 3 2 EamA-like transporter family UAA PF08449.11 KFM27646.1 - 0.0019 17.5 0.8 0.0019 17.5 0.8 1.7 2 1 0 2 2 2 1 UAA transporter family TPT PF03151.16 KFM27646.1 - 0.0024 17.2 1.9 0.0057 16.0 1.9 1.5 1 0 0 1 1 1 1 Triose-phosphate Transporter family PUNUT PF16913.5 KFM27646.1 - 0.045 13.0 12.1 0.008 15.4 7.7 2.0 2 1 1 3 3 3 0 Purine nucleobase transmembrane transport RCC1_2 PF13540.6 KFM27647.1 - 6.7e-16 57.6 23.5 2.8e-05 23.8 3.1 5.0 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 KFM27647.1 - 2.1e-13 50.7 15.4 1.3e-08 35.3 0.3 6.0 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat SNARE PF05739.19 KFM27648.1 - 3.3e-10 39.8 2.5 4.5e-10 39.4 0.3 2.3 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.25 KFM27648.1 - 1.7e-06 27.8 2.1 8.8e-06 25.5 2.1 2.1 1 1 0 1 1 1 1 Syntaxin MCPsignal PF00015.21 KFM27648.1 - 0.0053 16.6 1.4 0.0087 15.9 1.4 1.4 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin_2 PF14523.6 KFM27648.1 - 0.029 14.7 0.3 0.27 11.6 0.1 2.1 2 0 0 2 2 2 0 Syntaxin-like protein Synaptobrevin PF00957.21 KFM27648.1 - 0.05 13.4 0.3 1 9.2 0.0 2.2 2 0 0 2 2 2 0 Synaptobrevin RskA PF10099.9 KFM27648.1 - 4.3 7.6 8.2 0.89 9.8 4.4 1.8 2 0 0 2 2 2 0 Anti-sigma-K factor rskA RimM PF01782.18 KFM27649.1 - 2.9e-10 40.2 0.0 4.5e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 RimM N-terminal domain PRC PF05239.16 KFM27649.1 - 7.2e-08 32.4 0.0 1.1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 PRC-barrel domain RRP7 PF12923.7 KFM27650.1 - 9.9e-24 83.8 0.2 1.3e-23 83.4 0.2 1.1 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_3 PF08777.11 KFM27650.1 - 0.0049 16.9 0.0 0.027 14.5 0.0 2.0 1 1 1 2 2 2 1 RNA binding motif RRM_1 PF00076.22 KFM27650.1 - 0.021 14.7 1.1 0.024 14.4 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AlaDh_PNT_C PF01262.21 KFM27650.1 - 0.041 13.2 0.7 0.054 12.8 0.7 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain RRM_7 PF16367.5 KFM27650.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif DUF4407 PF14362.6 KFM27650.1 - 0.14 11.4 4.5 0.19 11.0 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SIMPL PF04402.14 KFM27652.1 - 6.8e-21 75.6 3.6 9.8e-21 75.1 3.6 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF541) DUF3486 PF11985.8 KFM27652.1 - 0.014 15.8 1.4 4 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3486) XhlA PF10779.9 KFM27652.1 - 0.14 12.4 0.1 0.26 11.5 0.1 1.4 1 0 0 1 1 1 0 Haemolysin XhlA Peptidase_M20 PF01546.28 KFM27653.1 - 2.5e-31 109.0 0.0 5.1e-31 108.0 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 KFM27653.1 - 9.2e-05 22.2 0.0 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 M20_dimer PF07687.14 KFM27653.1 - 0.00029 20.7 0.1 0.00058 19.7 0.1 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain F_actin_bind PF08919.10 KFM27654.1 - 0.051 13.7 0.0 0.082 13.0 0.0 1.4 1 0 0 1 1 1 0 F-actin binding MFS_1 PF07690.16 KFM27655.1 - 7.7e-13 48.1 28.8 2.1e-12 46.7 27.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily VQ PF05678.14 KFM27655.1 - 0.087 12.3 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 VQ motif Ras PF00071.22 KFM27656.1 - 9.3e-63 210.7 0.6 2e-62 209.6 0.6 1.6 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM27656.1 - 7.5e-35 119.7 0.1 2e-34 118.4 0.1 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase WD40 PF00400.32 KFM27656.1 - 2e-21 75.9 16.1 7e-06 26.7 0.7 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat Arf PF00025.21 KFM27656.1 - 5.4e-13 48.8 0.1 9.9e-13 47.9 0.1 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family ANAPC4_WD40 PF12894.7 KFM27656.1 - 2.6e-08 34.1 0.0 0.033 14.5 0.0 4.9 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain MMR_HSR1 PF01926.23 KFM27656.1 - 1.6e-06 28.2 0.1 4.9e-06 26.6 0.1 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFM27656.1 - 0.00036 20.5 0.3 0.083 12.8 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KFM27656.1 - 0.00049 19.7 0.1 0.0015 18.1 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Cytochrom_D1 PF02239.16 KFM27656.1 - 0.0045 15.6 0.4 0.072 11.6 0.1 2.4 2 0 0 2 2 2 1 Cytochrome D1 heme domain Gtr1_RagA PF04670.12 KFM27656.1 - 0.02 14.2 0.1 0.033 13.5 0.1 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 KFM27656.1 - 0.044 14.2 0.0 0.14 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 KFM27656.1 - 0.054 13.0 0.0 0.25 10.8 0.1 2.2 2 1 0 2 2 2 0 Ferrous iron transport protein B AAA_22 PF13401.6 KFM27656.1 - 0.071 13.4 0.1 0.29 11.4 0.1 2.0 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFM27656.1 - 0.13 12.8 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter PduV-EutP PF10662.9 KFM27656.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation EBV-NA3 PF05009.12 KFM27656.1 - 1.5 8.3 6.7 3 7.3 6.7 1.4 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) PQQ_3 PF13570.6 KFM27656.1 - 3.1 8.4 5.1 3.6 8.2 0.1 3.2 3 0 0 3 3 2 0 PQQ-like domain PriC PF07445.12 KFM27657.1 - 0.029 14.3 2.7 0.055 13.4 2.7 1.4 1 0 0 1 1 1 0 Primosomal replication protein priC PPR PF01535.20 KFM27657.1 - 0.038 14.2 0.3 11 6.5 0.0 2.6 2 0 0 2 2 2 0 PPR repeat TPR_19 PF14559.6 KFM27657.1 - 1.9 9.1 6.2 8.1 7.0 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat DFP PF04127.15 KFM27658.1 - 5.7e-17 62.2 0.0 2.4e-12 47.1 0.0 2.1 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein PAS_9 PF13426.7 KFM27658.1 - 0.029 14.6 0.0 0.078 13.2 0.0 1.7 1 0 0 1 1 1 0 PAS domain Spore_YhaL PF14147.6 KFM27658.1 - 0.11 12.2 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 Sporulation protein YhaL DDT PF02791.17 KFM27659.1 - 0.0049 17.2 0.1 0.0088 16.3 0.1 1.3 1 0 0 1 1 1 1 DDT domain Borrelia_P83 PF05262.11 KFM27659.1 - 0.07 11.6 7.7 0.11 11.0 7.7 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein WHIM1 PF15612.6 KFM27659.1 - 0.091 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 SET PF00856.28 KFM27660.1 - 7e-10 39.5 0.0 2.2e-09 37.9 0.0 2.0 1 1 0 1 1 1 1 SET domain Ribonuc_2-5A PF06479.12 KFM27662.1 - 0.035 14.3 0.4 0.068 13.4 0.4 1.4 1 0 0 1 1 1 0 Ribonuclease 2-5A FAS_I_H PF18314.1 KFM27662.1 - 0.061 12.9 0.2 0.12 12.0 0.2 1.4 1 0 0 1 1 1 0 Fatty acid synthase type I helical domain EcoEI_R_C PF08463.10 KFM27662.1 - 0.072 13.2 1.8 0.29 11.2 0.7 2.0 1 1 1 2 2 2 0 EcoEI R protein C-terminal Amidase PF01425.21 KFM27663.1 - 8.1e-39 133.8 0.0 7.9e-21 74.5 0.0 2.9 1 1 1 2 2 2 2 Amidase AraC_N PF06719.13 KFM27663.1 - 0.14 11.8 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 AraC-type transcriptional regulator N-terminus TAL_FSA PF00923.19 KFM27664.1 - 6.8e-91 304.6 0.0 1.9e-90 303.1 0.0 1.6 2 0 0 2 2 2 1 Transaldolase/Fructose-6-phosphate aldolase Amino_oxidase PF01593.24 KFM27665.1 - 4.6e-56 191.0 3.5 1.2e-55 189.6 3.5 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFM27665.1 - 6.7e-14 51.9 0.3 6.7e-14 51.9 0.3 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KFM27665.1 - 1.1e-07 31.3 4.5 1.7e-07 30.7 4.5 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KFM27665.1 - 1e-06 28.4 3.6 1.5e-06 27.8 3.6 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFM27665.1 - 9.3e-06 25.1 0.6 2.3e-05 23.8 0.9 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFM27665.1 - 2.3e-05 23.3 1.6 3.3e-05 22.8 1.6 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 KFM27665.1 - 4.8e-05 22.6 0.9 6.4e-05 22.2 0.9 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KFM27665.1 - 5.3e-05 22.4 2.9 5.5e-05 22.4 0.6 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 KFM27665.1 - 5.9e-05 22.5 0.6 5.9e-05 22.5 0.6 1.5 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KFM27665.1 - 9.7e-05 21.7 0.6 0.00017 20.9 0.6 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KFM27665.1 - 0.00021 21.0 8.6 0.0011 18.6 8.6 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KFM27665.1 - 0.0004 19.7 1.6 0.00073 18.9 1.6 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFM27665.1 - 0.0006 20.3 0.5 0.0018 18.8 0.5 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KFM27665.1 - 0.0087 15.4 1.3 0.017 14.4 1.3 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain XdhC_C PF13478.6 KFM27665.1 - 0.092 13.3 0.2 8.1 7.0 0.1 2.8 2 1 0 2 2 2 0 XdhC Rossmann domain PAP_assoc PF03828.19 KFM27666.1 - 2.2e-13 50.2 0.0 4.2e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KFM27666.1 - 2.9e-10 40.3 0.0 5.9e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KFM27666.1 - 0.00054 20.0 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase Prenyltrans PF00432.21 KFM27667.1 - 1.5e-41 139.8 13.5 2.9e-11 42.9 0.0 5.6 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat DUF2524 PF10732.9 KFM27667.1 - 0.21 11.9 1.6 0.37 11.1 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) EXS PF03124.14 KFM27668.1 - 3.7e-73 246.7 1.6 4.4e-73 246.5 1.6 1.0 1 0 0 1 1 1 1 EXS family Synaptobrevin PF00957.21 KFM27669.1 - 1.5e-09 37.5 0.0 2.3e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin ANAPC4_WD40 PF12894.7 KFM27669.1 - 0.00019 21.7 0.0 0.27 11.6 0.0 4.1 3 2 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFM27669.1 - 0.00089 20.0 1.3 0.27 12.2 0.0 3.8 4 0 0 4 4 4 1 WD domain, G-beta repeat Aminotran_1_2 PF00155.21 KFM27670.1 - 4.1e-65 220.3 0.0 5e-65 220.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KFM27670.1 - 4e-08 32.6 0.0 6e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KFM27670.1 - 1.2e-07 30.7 0.0 1.7e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KFM27670.1 - 1.5e-06 27.8 0.0 2.1e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_MocR PF12897.7 KFM27670.1 - 0.0046 15.8 0.0 0.0086 14.9 0.0 1.6 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Beta_elim_lyase PF01212.21 KFM27670.1 - 0.01 15.2 0.0 0.02 14.2 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase Glyco_transf_7C PF02709.14 KFM27671.1 - 4.1e-09 36.0 0.0 7.1e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.6 KFM27671.1 - 3.9e-06 26.5 0.0 6.3e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Aminotran_1_2 PF00155.21 KFM27673.1 - 1.8e-46 159.0 0.0 2.2e-46 158.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KFM27673.1 - 0.024 13.9 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Lactamase_B_2 PF12706.7 KFM27674.1 - 4.8e-34 117.7 0.1 6.6e-34 117.2 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KFM27674.1 - 3.5e-09 36.7 0.0 4.7e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Telomere_reg-2 PF10193.9 KFM27675.1 - 4.1e-05 24.0 0.0 8.8e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Telomere length regulation protein HEAT_2 PF13646.6 KFM27675.1 - 3 8.3 14.1 9.6 6.7 3.6 4.3 3 1 1 4 4 4 0 HEAT repeats TRAM_LAG1_CLN8 PF03798.16 KFM27676.1 - 1.7e-35 122.6 10.6 2e-35 122.3 10.6 1.1 1 0 0 1 1 1 1 TLC domain IPK PF03770.16 KFM27677.1 - 5.3e-33 114.5 0.0 5.8e-24 85.0 0.0 2.1 1 1 1 2 2 2 2 Inositol polyphosphate kinase Bromodomain PF00439.25 KFM27678.1 - 9.8e-20 70.4 0.1 1.7e-19 69.6 0.1 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 KFM27678.1 - 6.9e-07 29.5 0.0 1.4e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFM27678.1 - 1.7e-05 24.8 0.0 3.5e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFM27678.1 - 0.0019 18.6 0.0 0.0044 17.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain UFD1 PF03152.14 KFM27679.1 - 6.2e-77 256.9 0.0 7.4e-77 256.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 ER PF01133.17 KFM27680.1 - 6.9e-30 103.0 0.0 8.5e-30 102.7 0.0 1.1 1 0 0 1 1 1 1 Enhancer of rudimentary Robl_LC7 PF03259.17 KFM27680.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Roadblock/LC7 domain Calreticulin PF00262.18 KFM27681.1 - 7.8e-128 426.4 0.1 9.8e-128 426.1 0.1 1.1 1 0 0 1 1 1 1 Calreticulin family DUF1736 PF08409.11 KFM27683.1 - 9.4e-19 67.2 2.8 3.4e-18 65.4 2.8 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_17 PF13431.6 KFM27683.1 - 0.01 16.2 0.2 28 5.4 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFM27683.1 - 0.056 13.1 0.0 0.85 9.3 0.0 2.6 2 0 0 2 2 2 0 TPR repeat Semialdhyde_dh PF01118.24 KFM27684.1 - 2.6e-29 102.1 0.0 4.2e-29 101.4 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.18 KFM27684.1 - 1.5e-19 70.8 0.0 2.8e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain DapB_N PF01113.20 KFM27684.1 - 0.00077 19.6 0.0 0.0016 18.6 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.6 KFM27684.1 - 0.004 17.1 0.0 0.0071 16.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KFM27684.1 - 0.0054 17.0 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DXP_reductoisom PF02670.16 KFM27684.1 - 0.096 13.4 0.0 0.25 12.1 0.0 1.7 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase NmrA PF05368.13 KFM27684.1 - 0.19 11.3 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family RRM_1 PF00076.22 KFM27685.1 - 2.2e-14 53.0 0.2 3.1e-14 52.6 0.2 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFM27685.1 - 0.07 13.3 0.1 0.18 12.0 0.1 1.8 1 1 0 1 1 1 0 RNA recognition motif OTU PF02338.19 KFM27686.1 - 3.9e-22 79.1 1.5 2.9e-21 76.3 0.0 2.0 1 1 1 2 2 2 2 OTU-like cysteine protease Peptidase_C65 PF10275.9 KFM27686.1 - 2.9e-10 40.0 0.0 9.3e-08 31.8 0.0 2.1 1 1 1 2 2 2 2 Peptidase C65 Otubain SPEG_u2 PF16650.5 KFM27686.1 - 0.037 14.2 4.1 0.066 13.4 4.1 1.4 1 0 0 1 1 1 0 Unstructured region on SPEG complex protein MAGE_N PF12440.8 KFM27686.1 - 0.76 10.5 11.2 0.26 12.0 7.4 2.0 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal SPRY PF00622.28 KFM27687.1 - 5.6e-15 55.5 0.4 4.3e-09 36.5 0.1 2.1 2 0 0 2 2 2 2 SPRY domain Neuralized PF07177.12 KFM27687.1 - 0.13 12.3 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Neuralized NMU PF02070.15 KFM27687.1 - 0.77 9.7 2.1 1.4 8.9 0.0 2.3 3 0 0 3 3 3 0 Neuromedin U PRKCSH-like PF12999.7 KFM27688.1 - 3e-42 144.4 1.4 3.9e-42 144.0 0.1 1.8 2 1 0 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 KFM27688.1 - 5.9e-25 87.7 0.0 1.1e-24 86.9 0.0 1.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 KFM27688.1 - 1.3e-05 26.1 0.0 3.3e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein HOOK PF05622.12 KFM27688.1 - 0.00027 19.2 3.5 0.00034 18.9 3.5 1.0 1 0 0 1 1 1 1 HOOK protein AAA_13 PF13166.6 KFM27688.1 - 0.016 13.9 2.6 0.023 13.4 2.6 1.2 1 0 0 1 1 1 0 AAA domain MscS_porin PF12795.7 KFM27688.1 - 0.032 13.8 17.6 1.4 8.4 12.1 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Spc7 PF08317.11 KFM27688.1 - 0.089 11.7 11.1 0.093 11.6 5.1 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Ldl_recept_a PF00057.18 KFM27688.1 - 0.14 12.4 18.8 0.042 14.1 3.6 2.7 1 1 1 2 2 2 0 Low-density lipoprotein receptor domain class A HIP1_clath_bdg PF16515.5 KFM27688.1 - 0.66 10.6 11.4 9.4 6.9 4.6 2.8 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TPR_MLP1_2 PF07926.12 KFM27688.1 - 0.84 9.7 20.6 0.23 11.5 1.3 2.9 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein GAS PF13851.6 KFM27688.1 - 0.87 8.9 9.6 1.2 8.5 5.3 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 KFM27688.1 - 1.1 9.6 8.3 3.8 7.9 8.3 1.7 1 1 0 1 1 1 0 Fez1 RRF PF01765.19 KFM27688.1 - 9.9 6.1 6.8 26 4.8 1.8 2.1 2 0 0 2 2 2 0 Ribosome recycling factor MoCF_biosynth PF00994.24 KFM27689.1 - 2e-29 102.1 0.0 3.6e-29 101.3 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain PAPS_reduct PF01507.19 KFM27689.1 - 4.3e-27 95.3 0.0 1.1e-19 71.2 0.0 2.2 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family SfsA PF03749.13 KFM27690.1 - 7.7e-39 132.7 0.0 1e-38 132.4 0.0 1.1 1 0 0 1 1 1 1 Sugar fermentation stimulation protein RE domain SfsA_N PF17746.1 KFM27690.1 - 0.03 14.5 0.0 0.059 13.5 0.0 1.6 1 0 0 1 1 1 0 SfsA N-terminal OB domain ADK PF00406.22 KFM27691.1 - 2.8e-39 134.6 0.5 9.7e-37 126.4 0.5 2.1 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KFM27691.1 - 6.9e-25 88.0 0.8 1.1e-21 77.6 0.8 2.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFM27691.1 - 0.00022 21.4 0.2 0.00068 19.8 0.1 1.8 1 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KFM27691.1 - 0.00035 21.1 0.0 0.00065 20.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KFM27691.1 - 0.0067 15.7 0.1 0.011 15.1 0.1 1.5 1 0 0 1 1 1 1 Zeta toxin Ploopntkinase3 PF18751.1 KFM27691.1 - 0.034 14.1 0.1 0.051 13.5 0.1 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Mur_ligase_C PF02875.21 KFM27691.1 - 0.053 13.8 0.1 15 5.9 0.0 2.7 3 0 0 3 3 3 0 Mur ligase family, glutamate ligase domain AAA_19 PF13245.6 KFM27691.1 - 0.063 13.6 2.0 0.17 12.2 1.9 2.0 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KFM27691.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 1 0 1 1 1 0 NACHT domain Thymidylate_kin PF02223.17 KFM27691.1 - 0.13 11.9 0.6 4.5 6.9 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase Abhydrolase_1 PF00561.20 KFM27693.1 - 5.4e-10 39.4 0.0 8.9e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFM27693.1 - 0.00075 18.8 0.0 0.0012 18.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 SAC3_GANP PF03399.16 KFM27694.1 - 1.5e-05 24.5 0.0 1.9e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP family Acetyltransf_11 PF13720.6 KFM27696.1 - 0.1 13.0 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 UBA PF00627.31 KFM27698.1 - 8e-26 89.5 3.6 9.3e-15 54.2 0.4 2.6 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.11 KFM27698.1 - 2.9e-18 65.3 8.8 2.9e-18 65.3 8.8 1.8 2 0 0 2 2 2 1 XPC-binding domain DUF2999 PF11212.8 KFM27698.1 - 0.0038 17.5 0.5 2.4 8.5 0.5 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF2999) PfkB PF00294.24 KFM27699.1 - 3.7e-72 243.2 0.1 4.2e-72 243.0 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase acVLRF1 PF18859.1 KFM27699.1 - 0.13 12.5 0.3 1.9 8.8 0.0 2.2 2 0 0 2 2 2 0 Actinobacteria/chloroflexi VLRF1 release factor Peptidase_M16_C PF05193.21 KFM27699.1 - 0.18 11.8 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase M16 inactive domain Gpi1 PF05024.15 KFM27701.1 - 0.01 16.0 0.1 0.015 15.4 0.1 1.2 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) Pkinase PF00069.25 KFM27703.1 - 1.5e-66 224.5 0.0 1.8e-66 224.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM27703.1 - 3.9e-27 95.2 0.0 5.1e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFM27703.1 - 7.9e-05 22.7 0.7 0.00054 20.0 0.1 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family FTA2 PF13095.6 KFM27703.1 - 0.0014 18.3 0.0 0.0021 17.8 0.0 1.2 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KFM27703.1 - 0.0034 16.4 0.0 0.0048 15.9 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFM27703.1 - 0.0044 16.4 0.0 0.0071 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFM27703.1 - 0.009 15.4 0.0 0.036 13.4 0.0 1.8 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 KFM27703.1 - 0.072 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Ribosomal_L26 PF16906.5 KFM27704.1 - 3.5e-38 129.9 2.1 4.6e-38 129.6 2.1 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 KFM27704.1 - 2.1e-09 37.0 4.6 2.1e-09 37.0 4.6 2.0 2 0 0 2 2 2 1 KOW motif Methyltransf_11 PF08241.12 KFM27705.1 - 1.6e-17 63.9 0.0 3.2e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain ABC1 PF03109.16 KFM27705.1 - 2.1e-15 56.9 0.0 6e-15 55.5 0.0 1.8 1 1 0 1 1 1 1 ABC1 family Methyltransf_25 PF13649.6 KFM27705.1 - 4.1e-13 49.8 0.0 1e-12 48.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM27705.1 - 1.4e-08 35.4 0.0 2.8e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM27705.1 - 2e-05 24.5 0.0 3.6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM27705.1 - 2.6e-05 24.1 0.0 5.1e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFM27705.1 - 0.011 15.1 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Pkinase PF00069.25 KFM27705.1 - 0.07 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain DREV PF05219.12 KFM27705.1 - 0.094 11.8 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase NTF2 PF02136.20 KFM27709.1 - 1.6e-26 93.2 1.0 2.1e-26 92.9 1.0 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 KFM27709.1 - 8.6e-06 25.5 0.0 1.3e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Inositol_P PF00459.25 KFM27711.1 - 1.7e-50 172.1 0.0 2e-50 171.8 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Spermine_synth PF01564.17 KFM27712.1 - 1e-60 204.4 0.0 1.4e-60 203.9 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 KFM27712.1 - 2.8e-23 81.5 0.0 4.8e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 KFM27712.1 - 1.3e-05 25.8 0.0 2.4e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM27712.1 - 0.0091 15.8 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_30 PF05430.11 KFM27712.1 - 0.019 14.8 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_11 PF08241.12 KFM27712.1 - 0.021 15.4 0.0 0.058 14.0 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 KFM27712.1 - 0.06 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase TPT PF03151.16 KFM27713.1 - 2.8e-90 302.6 19.1 3.2e-90 302.4 19.1 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KFM27713.1 - 6.6e-09 36.0 28.1 1.4e-07 31.8 11.8 2.3 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KFM27713.1 - 0.039 13.2 15.5 0.025 13.8 13.7 1.5 1 1 0 1 1 1 0 UAA transporter family Orn_Arg_deC_N PF02784.16 KFM27714.1 - 1.2e-46 159.1 0.0 1.4e-46 158.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KFM27714.1 - 2.6e-23 82.1 0.0 3.1e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ala_racemase_N PF01168.20 KFM27714.1 - 2.1e-10 40.6 0.1 6.2e-10 39.1 0.1 1.7 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain E1-E2_ATPase PF00122.20 KFM27715.1 - 5e-34 117.4 0.2 7.8e-34 116.8 0.2 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KFM27715.1 - 2.6e-06 27.9 0.9 9.6e-06 26.0 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase tRNA-synt_His PF13393.6 KFM27716.1 - 3e-47 161.4 0.0 5.8e-47 160.5 0.0 1.5 2 0 0 2 2 2 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 KFM27716.1 - 0.00011 22.2 0.0 0.00022 21.3 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 KFM27716.1 - 0.00079 19.0 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs Pyrid_oxidase_2 PF13883.6 KFM27718.1 - 1e-23 84.1 0.0 1.7e-22 80.2 0.0 2.0 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Ribosomal_L20 PF00453.18 KFM27719.1 - 1.2e-39 134.7 3.1 1.3e-39 134.5 3.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L20 PSD2 PF07624.11 KFM27719.1 - 0.081 12.7 0.2 0.18 11.6 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1585) Dynamin_M PF01031.20 KFM27720.1 - 5.1e-52 176.9 0.0 2.1e-37 128.9 0.0 2.5 1 1 1 2 2 2 2 Dynamin central region Dynamin_N PF00350.23 KFM27720.1 - 9.8e-52 175.4 0.0 1.4e-51 174.9 0.0 1.2 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KFM27720.1 - 3.6e-25 87.9 0.2 6.3e-25 87.2 0.2 1.4 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KFM27720.1 - 8.9e-06 25.8 0.0 3.8e-05 23.7 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 KFM27720.1 - 0.13 12.5 0.1 0.78 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 KFM27720.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Arabino_trans_N PF17689.1 KFM27720.1 - 0.14 12.3 0.1 0.26 11.4 0.1 1.3 1 0 0 1 1 1 0 Arabinosyltransferase concanavalin like domain AAA_15 PF13175.6 KFM27720.1 - 0.15 11.7 0.0 0.24 11.1 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_16 PF13191.6 KFM27720.1 - 0.17 12.3 1.8 2.7 8.3 0.0 3.1 3 1 0 3 3 3 0 AAA ATPase domain PCO_ADO PF07847.12 KFM27721.1 - 8.7e-48 162.4 0.0 1.1e-47 162.1 0.0 1.1 1 0 0 1 1 1 1 PCO_ADO SLATT_2 PF18183.1 KFM27721.1 - 0.11 12.3 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 2 RTC_insert PF05189.13 KFM27722.1 - 1.8e-17 63.7 2.8 2.8e-17 63.1 2.8 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.21 KFM27722.1 - 4.3e-15 55.5 0.0 5.3e-15 55.2 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase Carb_kinase PF01256.17 KFM27723.1 - 1.2e-34 119.8 0.0 3.1e-34 118.5 0.0 1.5 1 1 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 KFM27723.1 - 0.16 11.3 0.0 0.39 10.0 0.0 1.6 1 1 0 1 1 1 0 Phosphomethylpyrimidine kinase DnaJ PF00226.31 KFM27724.1 - 7.2e-14 51.7 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain CPP1-like PF11833.8 KFM27724.1 - 0.25 11.0 0.1 0.38 10.4 0.1 1.3 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DnaJ PF00226.31 KFM27725.1 - 1.6e-12 47.4 0.0 3.9e-12 46.1 0.0 1.8 2 0 0 2 2 2 1 DnaJ domain Pro_isomerase PF00160.21 KFM27726.1 - 5.5e-48 163.2 0.0 9.7e-48 162.4 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 KFM27726.1 - 6.6e-12 45.8 0.0 0.0006 20.6 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM27726.1 - 0.0074 16.6 0.0 7.4 6.9 0.0 2.9 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFM27726.1 - 0.019 13.9 4.3 0.63 8.9 0.3 3.5 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ACT PF01842.25 KFM27727.1 - 6.1e-18 64.3 0.0 3.1e-05 23.6 0.0 4.4 4 0 0 4 4 4 3 ACT domain ACT_4 PF13291.6 KFM27727.1 - 2.2e-09 37.8 0.0 0.0072 16.9 0.0 4.4 4 0 0 4 4 4 2 ACT domain ACT_6 PF13740.6 KFM27727.1 - 3.8e-07 30.0 0.1 0.0034 17.3 0.0 3.5 3 0 0 3 3 3 2 ACT domain SecY PF00344.20 KFM27730.1 - 8.7e-25 87.6 2.9 1.1e-24 87.2 2.9 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 KFM27730.1 - 6.6e-16 57.9 0.1 1e-15 57.2 0.1 1.3 1 0 0 1 1 1 1 Plug domain of Sec61p Methyltransf_17 PF12692.7 KFM27730.1 - 0.18 11.8 0.0 0.27 11.2 0.0 1.1 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase MFS_1 PF07690.16 KFM27731.1 - 7.1e-15 54.8 36.6 7.1e-12 44.9 15.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily WDCP PF15390.6 KFM27733.1 - 5 5.4 5.5 7.4 4.8 5.5 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Ribosomal_L33 PF00471.20 KFM27734.1 - 1.4e-12 47.8 0.0 1.6e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L33 Pro_isomerase PF00160.21 KFM27736.1 - 2.1e-42 145.1 0.0 3.4e-42 144.4 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GCV_T PF01571.21 KFM27737.1 - 1.3e-07 31.3 0.0 7.1e-07 28.9 0.0 2.0 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain DNA_pol_lambd_f PF10391.9 KFM27738.1 - 2.3e-19 68.9 0.0 5.5e-19 67.7 0.0 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.6 KFM27738.1 - 6.2e-14 52.2 0.0 1.5e-13 50.9 0.0 1.7 1 1 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.6 KFM27738.1 - 0.00018 21.8 0.0 0.0005 20.4 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_B_thumb PF14791.6 KFM27738.1 - 0.00022 21.3 0.0 0.0011 19.1 0.0 2.1 2 0 0 2 2 2 1 DNA polymerase beta thumb PTCB-BRCT PF12738.7 KFM27738.1 - 0.0062 16.5 0.1 0.016 15.1 0.1 1.7 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 KFM27738.1 - 0.008 16.6 0.0 0.053 13.9 0.0 2.2 2 1 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KFM27738.1 - 0.026 14.9 0.0 0.069 13.5 0.0 1.8 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain NIBRIN_BRCT_II PF16508.5 KFM27738.1 - 0.14 12.4 0.0 0.41 11.0 0.0 1.7 1 0 0 1 1 1 0 Second BRCT domain on Nijmegen syndrome breakage protein LIG3_BRCT PF16759.5 KFM27738.1 - 0.18 12.1 0.5 2.1 8.7 0.5 2.3 1 1 0 1 1 1 0 DNA ligase 3 BRCT domain Sushi PF00084.20 KFM27740.1 - 0.062 13.9 0.0 2.7 8.7 0.0 2.4 2 0 0 2 2 2 0 Sushi repeat (SCR repeat) Sod_Fe_C PF02777.18 KFM27741.1 - 7.4e-41 138.5 0.1 1.6e-40 137.4 0.0 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KFM27741.1 - 2e-18 66.7 4.3 6.5e-18 65.0 4.3 1.8 1 1 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain DUF5617 PF18493.1 KFM27741.1 - 0.14 12.3 0.1 0.27 11.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5617) LRR_8 PF13855.6 KFM27742.1 - 6.2e-08 32.3 3.0 3.4e-05 23.5 0.3 4.7 7 0 0 7 7 7 2 Leucine rich repeat LRR_4 PF12799.7 KFM27742.1 - 4.7e-06 26.8 1.8 0.0038 17.6 0.1 5.4 5 1 1 6 6 6 1 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KFM27742.1 - 0.0012 18.7 0.1 0.0034 17.2 0.1 1.8 1 0 0 1 1 1 1 F-box-like zf-C2H2_9 PF16293.5 KFM27742.1 - 0.28 11.1 0.4 22 5.0 0.0 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) LRR_6 PF13516.6 KFM27742.1 - 5.3 7.4 7.4 21 5.5 1.2 4.5 5 0 0 5 5 5 0 Leucine Rich repeat Ran_BP1 PF00638.18 KFM27743.1 - 4.1e-16 59.3 0.0 2.1e-15 57.1 0.0 1.9 1 1 0 1 1 1 1 RanBP1 domain NUDIX PF00293.28 KFM27744.1 - 2.4e-11 43.8 1.0 2.4e-11 43.8 1.0 1.5 1 1 1 2 2 2 1 NUDIX domain Myb_DNA-binding PF00249.31 KFM27745.1 - 5e-06 26.6 0.0 9.5e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KFM27745.1 - 0.016 15.1 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 Myb DNA-binding like PTPA PF03095.15 KFM27746.1 - 3.5e-58 197.4 0.0 3.9e-58 197.3 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF1295 PF06966.12 KFM27747.1 - 7.7e-42 143.4 5.9 9.7e-42 143.1 5.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 KFM27747.1 - 0.015 15.7 0.4 0.072 13.5 0.0 2.3 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.17 KFM27747.1 - 0.019 13.8 1.4 0.026 13.3 0.2 1.9 2 1 0 2 2 2 0 Ergosterol biosynthesis ERG4/ERG24 family ALS_ss_C PF10369.9 KFM27748.1 - 7.5e-53 176.6 3.3 1.4e-25 89.3 0.2 3.3 3 0 0 3 3 3 2 Small subunit of acetolactate synthase ACT PF01842.25 KFM27748.1 - 7.6e-25 86.4 0.2 2.3e-13 49.6 0.0 2.8 2 0 0 2 2 2 2 ACT domain ACT_5 PF13710.6 KFM27748.1 - 1e-24 86.1 0.6 1.1e-12 47.6 0.0 3.9 4 0 0 4 4 4 2 ACT domain ACT_4 PF13291.6 KFM27748.1 - 5.2e-12 46.2 0.1 1.9e-05 25.2 0.0 2.7 2 0 0 2 2 2 2 ACT domain ACT_6 PF13740.6 KFM27748.1 - 2.3e-06 27.5 1.5 0.044 13.8 0.0 4.0 4 1 0 4 4 4 2 ACT domain NikR_C PF08753.11 KFM27748.1 - 0.0046 17.1 0.2 0.2 11.9 0.0 2.6 2 0 0 2 2 2 1 NikR C terminal nickel binding domain DUF2316 PF10078.9 KFM27748.1 - 0.027 14.7 0.0 0.12 12.6 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) HTH_34 PF13601.6 KFM27748.1 - 0.09 13.0 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain Sucrose_synth PF00862.19 KFM27749.1 - 7.4e-113 377.7 0.4 6.7e-58 196.3 0.8 2.2 1 1 1 2 2 2 2 Sucrose synthase Glycos_transf_1 PF00534.20 KFM27749.1 - 3.1e-27 95.2 0.0 5.7e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KFM27749.1 - 1.1e-08 35.6 0.0 3.7e-08 33.9 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KFM27749.1 - 5e-06 26.8 0.0 1.2e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Sucrose_synth PF00862.19 KFM27750.1 - 3.2e-131 438.3 0.0 4.3e-131 437.9 0.0 1.0 1 0 0 1 1 1 1 Sucrose synthase Peptidase_M17 PF00883.21 KFM27751.1 - 3.6e-78 263.0 3.0 6.1e-78 262.2 3.0 1.4 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 KFM27751.1 - 5.4e-18 65.1 2.2 5.4e-18 65.1 2.2 2.4 2 0 0 2 2 2 1 Cytosol aminopeptidase family, N-terminal domain PDZ_6 PF17820.1 KFM27751.1 - 0.01 15.7 0.1 0.026 14.4 0.1 1.7 1 0 0 1 1 1 0 PDZ domain Peptidase_M17 PF00883.21 KFM27752.1 - 1.9e-87 293.4 5.0 2.3e-87 293.2 5.0 1.0 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain PDZ_6 PF17820.1 KFM27752.1 - 0.0053 16.6 0.1 0.013 15.4 0.1 1.7 1 0 0 1 1 1 1 PDZ domain TPR_12 PF13424.6 KFM27753.1 - 1.3e-14 54.2 95.4 0.0064 16.8 0.6 14.8 11 4 3 14 14 14 8 Tetratricopeptide repeat TPR_2 PF07719.17 KFM27753.1 - 2.5e-13 49.0 76.4 0.00018 21.3 0.2 17.4 19 0 0 19 19 18 6 Tetratricopeptide repeat TPR_1 PF00515.28 KFM27753.1 - 1.1e-11 44.0 23.3 0.00068 19.4 0.0 12.1 13 0 0 13 13 13 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFM27753.1 - 4.4e-11 42.1 22.6 0.084 13.1 0.0 12.6 14 0 0 14 14 12 3 Tetratricopeptide repeat TPR_17 PF13431.6 KFM27753.1 - 9e-11 41.4 30.9 0.0028 17.9 0.1 11.8 12 1 0 12 12 12 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFM27753.1 - 1.3e-10 40.8 25.9 5.3e-06 26.0 0.1 9.7 9 1 1 10 10 10 4 TPR repeat TPR_19 PF14559.6 KFM27753.1 - 2.6e-09 37.5 7.4 1.4e-05 25.5 0.4 15.6 12 4 3 15 15 14 7 Tetratricopeptide repeat TPR_16 PF13432.6 KFM27753.1 - 1.4e-08 35.2 7.3 1.4e-08 35.2 7.3 19.3 15 5 6 23 23 20 8 Tetratricopeptide repeat TPR_14 PF13428.6 KFM27753.1 - 4.8e-05 23.8 22.3 0.001 19.7 1.9 24.9 17 7 9 26 26 24 11 Tetratricopeptide repeat TPR_9 PF13371.6 KFM27753.1 - 0.00089 19.4 2.4 0.00089 19.4 2.4 11.6 11 3 2 13 13 12 5 Tetratricopeptide repeat TPR_7 PF13176.6 KFM27753.1 - 0.015 15.3 26.3 24 5.3 1.1 10.6 10 0 0 10 10 10 0 Tetratricopeptide repeat DUF4810 PF16068.5 KFM27753.1 - 0.24 12.0 1.6 14 6.3 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4810) DUF3856 PF12968.7 KFM27753.1 - 5.7 7.0 21.3 0.63 10.1 1.1 4.6 5 0 0 5 5 5 0 Domain of Unknown Function (DUF3856) TPR_19 PF14559.6 KFM27755.1 - 2.9e-08 34.1 1.6 9.1e-07 29.3 0.2 5.8 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFM27755.1 - 3.9e-05 24.1 1.5 0.00015 22.3 0.5 9.4 6 4 5 11 11 11 4 Tetratricopeptide repeat TPR_17 PF13431.6 KFM27755.1 - 5.1e-05 23.4 3.4 14 6.3 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM27755.1 - 0.018 15.2 3.0 2.2 8.6 0.1 3.3 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.10 KFM27755.1 - 0.021 13.8 0.1 0.03 13.3 0.1 1.1 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_4 PF07721.14 KFM27755.1 - 0.061 14.0 1.3 0.061 14.0 1.3 6.8 7 0 0 7 7 6 0 Tetratricopeptide repeat FLYWCH_u PF16662.5 KFM27755.1 - 0.062 13.4 0.1 0.5 10.5 0.0 2.5 2 0 0 2 2 2 0 FLYWCH-type zinc finger-containing protein 1 Fis1_TPR_C PF14853.6 KFM27755.1 - 0.063 13.4 0.1 0.25 11.4 0.0 2.0 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat DUF4919 PF16266.5 KFM27755.1 - 0.11 12.4 0.0 0.43 10.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4919) TPR_1 PF00515.28 KFM27755.1 - 0.21 11.4 3.7 17 5.5 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3856 PF12968.7 KFM27755.1 - 0.23 11.5 4.8 0.8 9.8 1.4 2.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF3856) TPR_2 PF07719.17 KFM27755.1 - 1 9.6 0.0 1 9.6 0.0 6.4 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFM27755.1 - 6.8 7.1 26.3 0.53 10.6 0.1 5.8 5 1 1 6 6 6 0 Tetratricopeptide repeat TB2_DP1_HVA22 PF03134.19 KFM27756.1 - 4.4e-19 68.2 0.0 6.2e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family tRNA-synt_1b PF00579.25 KFM27757.1 - 5.9e-78 262.1 0.0 8.7e-78 261.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) HMG_box PF00505.19 KFM27757.1 - 6.2e-08 33.0 0.0 1.2e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFM27757.1 - 4e-07 30.5 0.1 8.9e-07 29.4 0.1 1.5 1 0 0 1 1 1 1 HMG-box domain CBFD_NFYB_HMF PF00808.23 KFM27757.1 - 3.4e-05 24.0 0.0 9.2e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 KFM27757.1 - 0.098 12.8 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Nuc_sug_transp PF04142.15 KFM27758.1 - 4.3e-35 121.4 10.9 2.1e-34 119.2 10.9 1.8 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 KFM27758.1 - 1.1e-05 25.6 2.0 1.1e-05 25.6 2.0 3.1 2 1 0 2 2 2 1 EamA-like transporter family TPT PF03151.16 KFM27758.1 - 0.0073 15.7 0.1 0.0073 15.7 0.1 2.2 3 0 0 3 3 3 1 Triose-phosphate Transporter family DUF4512 PF14975.6 KFM27758.1 - 0.022 15.6 0.1 0.043 14.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) DNA_RNApol_7kD PF03604.13 KFM27759.1 - 2.5e-16 59.1 7.8 3.2e-16 58.7 7.8 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit UPF0547 PF10571.9 KFM27759.1 - 0.0056 16.7 0.9 0.058 13.5 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised protein family UPF0547 Rubredoxin_2 PF18073.1 KFM27759.1 - 0.01 15.5 2.0 2.1 8.1 0.2 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain zinc_ribbon_13 PF09855.9 KFM27759.1 - 0.014 15.5 0.2 0.014 15.5 0.2 1.7 1 1 1 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) Zn_ribbon_recom PF13408.6 KFM27759.1 - 0.017 15.7 4.0 0.45 11.1 0.6 2.1 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Zn_ribbon_SprT PF17283.2 KFM27759.1 - 0.026 14.4 3.4 0.04 13.8 3.4 1.4 1 0 0 1 1 1 0 SprT-like zinc ribbon domain DZR PF12773.7 KFM27759.1 - 0.027 14.5 0.2 0.036 14.1 0.2 1.2 1 0 0 1 1 1 0 Double zinc ribbon HypA PF01155.19 KFM27759.1 - 0.031 14.3 0.2 0.036 14.1 0.2 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_2 PF13240.6 KFM27759.1 - 0.035 13.8 2.2 0.15 11.8 2.2 1.9 1 1 0 1 1 1 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 KFM27759.1 - 0.14 12.3 1.8 0.36 11.0 1.7 1.8 1 1 1 2 2 2 0 Zinc ribbon domain zf-trcl PF13451.6 KFM27759.1 - 0.69 9.9 4.0 3 7.8 0.1 2.1 1 1 1 2 2 2 0 Probable zinc-ribbon domain Thioredoxin_8 PF13905.6 KFM27760.1 - 2.2e-25 88.8 0.0 3e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 KFM27760.1 - 2.1e-08 34.0 0.0 3.1e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KFM27760.1 - 5.6e-08 32.7 0.0 8.9e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin PF00085.20 KFM27760.1 - 2.6e-06 27.3 0.0 1.2e-05 25.3 0.0 1.9 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 KFM27760.1 - 2.1e-05 24.9 0.0 0.00012 22.5 0.0 2.0 1 1 1 2 2 2 1 Thioredoxin-like domain DUF2062 PF09835.9 KFM27760.1 - 0.026 14.4 0.7 0.047 13.5 0.7 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) Glutaredoxin PF00462.24 KFM27760.1 - 0.071 13.3 0.3 0.37 11.0 0.3 2.1 1 1 0 1 1 1 0 Glutaredoxin DNA_pol_viral_C PF00336.18 KFM27760.1 - 0.087 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain DUF899 PF05988.12 KFM27760.1 - 0.11 12.0 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) TraF PF13728.6 KFM27760.1 - 0.12 12.2 0.0 0.27 11.0 0.0 1.6 1 1 0 1 1 1 0 F plasmid transfer operon protein SCO1-SenC PF02630.14 KFM27760.1 - 0.19 11.7 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 SCO1/SenC Exo_endo_phos PF03372.23 KFM27761.1 - 8.5e-06 25.5 0.0 2.3e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Myb_DNA-bind_7 PF15963.5 KFM27762.1 - 1.2e-25 89.2 0.0 2.4e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 KFM27762.1 - 2.4e-06 27.6 0.0 4.4e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF3325 PF11804.8 KFM27762.1 - 0.0018 18.4 5.5 0.21 11.8 0.5 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3325) Molybdopterin_N PF18364.1 KFM27762.1 - 0.0051 16.8 3.6 0.27 11.3 0.0 2.9 3 0 0 3 3 3 2 Molybdopterin oxidoreductase N-terminal domain Myb_DNA-bind_6 PF13921.6 KFM27762.1 - 0.013 15.8 0.0 0.026 14.8 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain P5CR_dimer PF14748.6 KFM27762.1 - 0.1 12.9 5.2 2.7 8.3 0.2 2.7 2 1 1 3 3 3 0 Pyrroline-5-carboxylate reductase dimerisation SANT_DAMP1_like PF16282.5 KFM27762.1 - 0.18 12.0 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 MA3 PF02847.17 KFM27764.1 - 1e-18 67.3 0.0 2.7e-18 66.0 0.0 1.7 1 0 0 1 1 1 1 MA3 domain CK2S PF15011.6 KFM27765.1 - 2.9e-09 37.0 0.0 3.8e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Casein Kinase 2 substrate SpoU_methylase PF00588.19 KFM27767.1 - 1.2e-26 93.6 0.0 2.2e-26 92.7 0.0 1.5 1 0 0 1 1 1 1 SpoU rRNA Methylase family SLBP_RNA_bind PF15247.6 KFM27769.1 - 2.5e-31 107.6 5.4 4.2e-31 106.9 5.4 1.4 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain UPF0004 PF00919.20 KFM27771.1 - 1.9e-28 98.4 0.0 3.2e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 KFM27771.1 - 1.4e-26 93.8 0.0 2.7e-26 92.9 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily TRAM PF01938.20 KFM27771.1 - 1e-05 25.4 0.0 2.2e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 TRAM domain MgtE PF01769.16 KFM27772.1 - 2.6e-26 92.4 6.0 2.6e-26 92.4 6.0 1.6 2 0 0 2 2 2 1 Divalent cation transporter FixH PF05751.11 KFM27772.1 - 2.5 8.1 5.4 14 5.7 0.4 2.2 2 0 0 2 2 2 0 FixH DUF2892 PF11127.8 KFM27772.1 - 5.2 7.2 13.3 7.9 6.6 6.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2892) SMC_N PF02463.19 KFM27774.1 - 1.4e-57 194.7 0.0 4.5e-57 193.0 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KFM27774.1 - 7.3e-12 45.6 0.1 3.8e-10 40.1 0.0 3.0 1 1 1 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KFM27774.1 - 7.8e-12 45.6 0.2 5.6e-08 32.9 0.0 2.7 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KFM27774.1 - 1.5e-11 45.2 10.3 1.5e-11 45.2 10.3 4.6 3 2 0 3 3 2 1 AAA domain AAA_15 PF13175.6 KFM27774.1 - 5e-09 36.3 0.0 1.5e-08 34.7 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KFM27774.1 - 1e-06 28.4 0.0 2.2e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF1848 PF08902.11 KFM27774.1 - 0.33 10.6 1.0 0.82 9.3 1.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) ABC_tran PF00005.27 KFM27774.1 - 0.37 11.3 9.1 0.37 11.3 0.0 4.4 4 2 0 4 4 4 0 ABC transporter SOGA PF11365.8 KFM27774.1 - 1.1 10.4 0.0 1.1 10.4 0.0 7.1 5 2 2 7 7 6 0 Protein SOGA SfsA PF03749.13 KFM27774.1 - 1.7 8.5 6.2 0.32 10.9 1.8 2.1 2 0 0 2 2 2 0 Sugar fermentation stimulation protein RE domain NPV_P10 PF05531.12 KFM27774.1 - 3 8.4 9.0 5.7 7.5 0.1 4.2 5 0 0 5 5 4 0 Nucleopolyhedrovirus P10 protein Aida_C2 PF14186.6 KFM27775.1 - 7e-26 90.6 0.0 1.4e-25 89.7 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal adhesion TP6A_N PF04406.14 KFM27775.1 - 6.3e-21 74.1 0.3 1.5e-20 72.9 0.1 1.8 2 0 0 2 2 2 1 Type IIB DNA topoisomerase TRM13 PF05206.14 KFM27776.1 - 3.2e-50 171.1 0.0 4e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TRM13 Methyltransf_32 PF13679.6 KFM27776.1 - 0.00017 21.6 6.6 0.0053 16.8 6.6 2.3 1 1 0 1 1 1 1 Methyltransferase domain NIR_SIR PF01077.22 KFM27778.1 - 5.2e-48 162.6 0.0 6.5e-42 142.7 0.0 2.3 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 KFM27778.1 - 2.6e-28 97.7 0.2 1.7e-14 53.4 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain MoaE PF02391.17 KFM27779.1 - 2.7e-36 124.3 0.3 3.3e-36 124.0 0.3 1.1 1 0 0 1 1 1 1 MoaE protein Aminotran_3 PF00202.21 KFM27780.1 - 9.4e-113 376.9 0.0 1.5e-112 376.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Ctr PF04145.15 KFM27780.1 - 3.8e-21 76.2 0.0 7e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 Ctr copper transporter family Aminotran_3 PF00202.21 KFM27781.1 - 2.6e-95 319.5 0.0 5.1e-93 311.9 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class-III Aminotran_1_2 PF00155.21 KFM27781.1 - 0.11 11.7 0.0 0.33 10.1 0.0 1.7 2 0 0 2 2 2 0 Aminotransferase class I and II MMADHC PF10229.9 KFM27782.1 - 3.2e-32 112.4 0.0 4e-32 112.1 0.0 1.0 1 0 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type D protein DEAD PF00270.29 KFM27783.1 - 7.5e-37 126.8 0.0 1.6e-36 125.7 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM27783.1 - 4.8e-24 84.8 0.0 8.5e-24 84.0 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SPRY PF00622.28 KFM27783.1 - 9e-20 71.0 0.0 1.6e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 SPRY domain WD40 PF00400.32 KFM27784.1 - 0.00081 20.2 1.3 0.019 15.8 0.1 3.6 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM27784.1 - 0.014 15.7 0.0 0.08 13.3 0.0 2.3 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Glyco_transf_5 PF08323.11 KFM27785.1 - 2.5e-61 207.5 0.1 3.5e-61 207.0 0.1 1.2 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KFM27785.1 - 1.7e-16 60.2 0.0 2.6e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KFM27785.1 - 1.7e-13 51.2 0.0 3.4e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KFM27785.1 - 0.00029 20.9 1.2 0.0016 18.4 0.4 2.4 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KFM27785.1 - 0.0035 17.8 11.4 0.0079 16.7 8.2 2.9 1 1 1 2 2 2 1 Glycosyl transferase 4-like domain SBF PF01758.16 KFM27786.1 - 1.5e-33 116.1 13.9 2.6e-33 115.3 13.9 1.4 1 0 0 1 1 1 1 Sodium Bile acid symporter family SBF_like PF13593.6 KFM27786.1 - 3.6e-13 49.5 21.6 4.9e-13 49.1 21.6 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Mem_trans PF03547.18 KFM27786.1 - 5.8 5.2 11.6 0.44 8.9 6.4 1.7 2 0 0 2 2 2 0 Membrane transport protein Herpes_US9 PF06072.11 KFM27786.1 - 7.6 6.5 6.7 4.7 7.1 0.6 3.0 2 1 1 3 3 3 0 Alphaherpesvirus tegument protein US9 Tim44 PF04280.15 KFM27788.1 - 2.4e-33 115.3 0.0 3.3e-33 114.9 0.0 1.2 1 0 0 1 1 1 1 Tim44-like domain MM_CoA_mutase PF01642.22 KFM27789.1 - 1e-229 763.4 0.2 1.3e-229 763.0 0.2 1.1 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.19 KFM27789.1 - 1.8e-13 50.6 2.0 4.5e-13 49.3 2.0 1.7 1 0 0 1 1 1 1 B12 binding domain DUF2163 PF09931.9 KFM27789.1 - 0.061 13.5 0.4 0.15 12.2 0.4 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2163) Bac_DNA_binding PF00216.21 KFM27790.1 - 4.8e-11 42.7 0.0 5.9e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-CCDC81_bac_2 PF18175.1 KFM27790.1 - 0.0054 16.6 0.0 0.0091 15.8 0.0 1.4 1 0 0 1 1 1 1 CCDC81-like prokaryotic HU domain 2 BST2 PF16716.5 KFM27790.1 - 0.042 14.4 0.2 0.069 13.7 0.2 1.3 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 HU-HIG PF18291.1 KFM27790.1 - 0.17 12.0 0.0 0.24 11.5 0.0 1.3 1 1 0 1 1 1 0 HU domain fused to wHTH, Ig, or Glycine-rich motif RBFA PF02033.18 KFM27791.1 - 6.6e-22 77.9 0.2 8.4e-22 77.6 0.2 1.1 1 0 0 1 1 1 1 Ribosome-binding factor A Calici_PP_N PF08405.11 KFM27791.1 - 0.012 14.4 0.0 0.015 14.1 0.0 1.1 1 0 0 1 1 1 0 Viral polyprotein N-terminal FAD-oxidase_C PF02913.19 KFM27792.1 - 1.5e-54 185.2 0.0 4.2e-54 183.8 0.0 1.6 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KFM27792.1 - 1.2e-30 106.0 4.1 2.2e-30 105.2 4.1 1.4 1 0 0 1 1 1 1 FAD binding domain UPF0086 PF01868.16 KFM27793.1 - 1.2e-07 31.5 0.0 1.8e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function UPF0086 TfuA PF07812.12 KFM27793.1 - 0.02 14.6 0.0 2.9 7.6 0.0 2.1 1 1 1 2 2 2 0 TfuA-like protein BAT PF15915.5 KFM27793.1 - 0.038 13.8 0.5 8.3 6.3 0.1 2.3 2 0 0 2 2 2 0 GAF and HTH_10 associated domain Isochorismatase PF00857.20 KFM27794.1 - 6.3e-23 81.8 4.5 1.1e-21 77.9 1.3 2.1 1 1 1 2 2 2 2 Isochorismatase family PaaX PF07848.12 KFM27794.1 - 0.024 14.8 0.1 0.058 13.6 0.1 1.6 1 0 0 1 1 1 0 PaaX-like protein HTH_41 PF14502.6 KFM27794.1 - 0.037 13.7 0.1 0.092 12.4 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain U1snRNP70_N PF12220.8 KFM27795.1 - 0.23 12.1 2.4 0.38 11.4 2.4 1.3 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Radical_SAM PF04055.21 KFM27796.1 - 1.1e-17 64.9 0.0 2.3e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 KFM27796.1 - 0.01 16.0 0.0 0.018 15.2 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S single cluster domain Fer4_12 PF13353.6 KFM27796.1 - 0.018 15.3 0.0 0.028 14.7 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S single cluster domain SE PF08491.10 KFM27796.1 - 0.043 12.9 0.0 0.069 12.2 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase ABC_tran PF00005.27 KFM27797.1 - 6.9e-24 84.9 0.0 1e-23 84.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KFM27797.1 - 0.00023 21.1 0.1 0.38 10.5 0.1 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 KFM27797.1 - 0.019 14.7 0.1 0.035 13.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KFM27797.1 - 0.04 13.7 0.1 0.073 12.8 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.6 KFM27797.1 - 0.11 12.9 0.3 0.25 11.7 0.3 1.5 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 KFM27797.1 - 0.13 11.7 0.1 0.54 9.7 0.0 1.9 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain DJ-1_PfpI PF01965.24 KFM27798.1 - 3e-47 160.5 0.0 3.5e-47 160.3 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 KFM27798.1 - 6.2e-05 22.8 0.0 0.00014 21.7 0.0 1.6 1 1 1 2 2 2 1 Glutamine amidotransferase class-I ThiJ_like PF17124.5 KFM27798.1 - 6.7e-05 22.7 0.1 0.0026 17.5 0.1 2.1 1 1 0 1 1 1 1 ThiJ/PfpI family-like GATase_5 PF13507.6 KFM27798.1 - 9.5e-05 21.6 0.0 0.00033 19.8 0.0 1.9 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 KFM27798.1 - 0.0013 18.6 0.0 0.018 14.8 0.0 2.1 1 1 0 1 1 1 1 Peptidase C26 NFACT-C PF11923.8 KFM27798.1 - 0.0018 18.2 0.0 0.0029 17.5 0.0 1.3 1 0 0 1 1 1 1 NFACT protein C-terminal domain GATase_3 PF07685.14 KFM27798.1 - 0.0049 16.5 0.0 0.0072 16.0 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Nop10p PF04135.12 KFM27799.1 - 9.4e-21 73.6 1.1 1.1e-20 73.4 1.1 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Galactosyl_T PF01762.21 KFM27800.1 - 6.2e-27 94.7 0.0 8e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase RRM_1 PF00076.22 KFM27801.1 - 1.1e-41 140.4 0.0 1.2e-16 60.2 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SOUL PF04832.12 KFM27801.1 - 3.3e-33 115.2 0.0 4.9e-33 114.7 0.0 1.3 1 0 0 1 1 1 1 SOUL heme-binding protein DUF2358 PF10184.9 KFM27801.1 - 1.4e-16 60.8 0.0 2.5e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) RRM_7 PF16367.5 KFM27801.1 - 0.0021 18.1 0.0 0.75 10.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KFM27801.1 - 0.0053 16.7 0.1 0.03 14.3 0.0 2.1 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Nuc_sug_transp PF04142.15 KFM27802.1 - 1.1e-32 113.4 8.8 1.6e-32 113.0 8.8 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 KFM27802.1 - 5.5 7.2 18.5 0.031 14.4 2.5 2.9 2 1 0 2 2 2 0 EamA-like transporter family ARS2 PF04959.13 KFM27803.1 - 1.8e-08 35.0 1.4 1.8e-08 35.0 1.4 2.8 2 1 2 4 4 4 1 Arsenite-resistance protein 2 DUF3546 PF12066.8 KFM27803.1 - 5.4e-06 26.6 0.6 1.4e-05 25.3 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) GRP PF07172.11 KFM27803.1 - 2.5 8.9 16.9 7.6 7.3 0.4 2.6 2 0 0 2 2 2 0 Glycine rich protein family CIAPIN1 PF05093.13 KFM27804.1 - 8.6e-18 64.7 12.5 1.5e-15 57.5 2.1 2.3 1 1 1 2 2 2 2 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis CASP_C PF08172.12 KFM27805.1 - 2.9e-45 154.6 2.0 2.9e-45 154.6 2.0 4.6 2 2 2 4 4 4 1 CASP C terminal BLOC1_2 PF10046.9 KFM27805.1 - 0.011 16.0 2.9 0.011 16.0 2.9 4.8 5 3 0 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Exo84_C PF16528.5 KFM27805.1 - 2.2 8.1 12.3 4.6 7.0 7.6 2.6 2 0 0 2 2 2 0 Exocyst component 84 C-terminal MPS2 PF17060.5 KFM27805.1 - 10 5.3 13.2 9.5 5.4 11.1 1.9 1 1 1 2 2 2 0 Monopolar spindle protein 2 Polyketide_cyc PF03364.20 KFM27806.1 - 2e-15 57.1 0.0 2.9e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 KFM27806.1 - 0.0035 17.6 0.0 0.018 15.3 0.0 2.0 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport COXG PF06240.13 KFM27806.1 - 0.006 16.3 0.0 0.0094 15.7 0.0 1.4 1 0 0 1 1 1 1 Carbon monoxide dehydrogenase subunit G (CoxG) CactinC_cactus PF09732.9 KFM27807.1 - 3.5e-59 198.2 8.0 4.3e-59 197.9 8.0 1.1 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.9 KFM27808.1 - 1.7e-34 119.3 0.0 1.7e-34 119.3 0.0 2.6 3 0 0 3 3 3 1 Conserved mid region of cactin TFIIE_alpha PF02002.17 KFM27809.1 - 0.00068 19.5 0.3 0.002 18.0 0.3 1.7 1 1 0 1 1 1 1 TFIIE alpha subunit HTH_5 PF01022.20 KFM27809.1 - 0.014 15.2 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Rrf2 PF02082.20 KFM27809.1 - 0.016 15.6 0.0 0.2 12.0 0.0 2.3 2 0 0 2 2 2 0 Transcriptional regulator HTH_20 PF12840.7 KFM27809.1 - 0.023 14.8 0.4 0.087 12.9 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_36 PF13730.6 KFM27809.1 - 0.034 14.1 0.0 0.069 13.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain TF_Zn_Ribbon PF08271.12 KFM27809.1 - 0.062 12.8 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding MarR_2 PF12802.7 KFM27809.1 - 0.092 12.6 1.7 0.27 11.2 0.1 2.3 2 0 0 2 2 2 0 MarR family DUF4715 PF15835.5 KFM27809.1 - 0.15 12.1 0.6 0.27 11.3 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4715) DUF2250 PF10007.9 KFM27809.1 - 0.16 12.1 0.0 1.3 9.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) IRK_C PF17655.1 KFM27810.1 - 4.2e-51 173.0 0.0 3e-32 111.6 0.0 2.2 2 0 0 2 2 2 2 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KFM27810.1 - 1.5e-13 50.7 9.1 1.5e-12 47.5 9.1 2.1 1 1 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 KFM27810.1 - 5.3e-05 23.1 8.1 0.0001 22.2 8.1 1.5 1 0 0 1 1 1 1 Ion channel DUF3327 PF11806.8 KFM27811.1 - 0.11 13.2 0.0 0.19 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3327) Mito_carr PF00153.27 KFM27812.1 - 1e-57 192.0 0.8 1.5e-22 79.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KFM27812.1 - 0.015 14.5 0.1 0.18 10.9 0.0 2.3 2 1 0 2 2 2 0 Gammaproteobacterial serine protease AAA PF00004.29 KFM27814.1 - 1.7e-12 47.9 0.0 2.8e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Myb_DNA-bind_6 PF13921.6 KFM27814.1 - 0.032 14.5 0.1 0.08 13.2 0.1 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 KFM27814.1 - 0.087 12.9 1.4 0.17 11.9 1.4 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 KFM27814.1 - 0.11 12.8 0.2 0.25 11.6 0.2 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Alba PF01918.21 KFM27815.1 - 4.7e-05 23.1 0.0 7.6e-05 22.5 0.0 1.4 1 1 1 2 2 2 1 Alba Qn_am_d_aIII PF09099.10 KFM27815.1 - 0.13 12.6 0.0 0.16 12.4 0.0 1.1 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain III BSD PF03909.17 KFM27816.1 - 4.9e-10 39.3 0.0 8.1e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 BSD domain Lipase_3 PF01764.25 KFM27819.1 - 3.5e-09 36.7 0.0 3e-07 30.4 0.0 2.2 2 0 0 2 2 2 2 Lipase (class 3) UPF0220 PF05255.11 KFM27819.1 - 0.17 11.4 0.1 0.29 10.7 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0220) Pantoate_ligase PF02569.15 KFM27820.1 - 3.1e-72 243.0 0.0 3.5e-72 242.8 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Prenyltrans PF00432.21 KFM27821.1 - 7.2e-61 201.6 21.7 8.9e-13 47.7 0.5 6.0 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 KFM27821.1 - 0.00021 20.5 0.0 0.36 9.9 0.0 3.3 2 1 1 3 3 3 2 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 KFM27821.1 - 0.0005 19.3 0.1 0.013 14.6 0.0 2.4 1 1 1 2 2 2 1 Squalene-hopene cyclase C-terminal domain Methyltrn_RNA_3 PF02598.17 KFM27822.1 - 7.2e-87 291.5 0.0 9.5e-87 291.1 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase Peptidase_M14 PF00246.24 KFM27822.1 - 3.4e-46 158.3 0.0 4.8e-46 157.9 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase CarboxypepD_reg PF13620.6 KFM27822.1 - 1.1e-05 25.6 2.2 2e-05 24.8 0.6 2.2 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain AstE_AspA PF04952.14 KFM27822.1 - 5.9e-05 22.3 0.0 0.00013 21.1 0.0 1.5 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family DUF2817 PF10994.8 KFM27822.1 - 0.00054 19.5 0.0 0.00087 18.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) CarbopepD_reg_2 PF13715.6 KFM27822.1 - 0.015 15.3 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 CarboxypepD_reg-like domain WD40 PF00400.32 KFM27823.1 - 9e-40 133.9 12.8 4.8e-07 30.4 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM27823.1 - 1.7e-10 41.0 0.0 0.0093 16.2 0.0 4.7 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFM27823.1 - 0.00028 19.7 0.5 2.7 6.5 0.0 3.7 2 1 0 3 3 3 3 Nucleoporin Nup120/160 VID27 PF08553.10 KFM27823.1 - 0.0012 18.0 0.0 0.0023 17.0 0.0 1.5 2 0 0 2 2 2 1 VID27 C-terminal WD40-like domain Ge1_WD40 PF16529.5 KFM27823.1 - 0.0013 17.8 3.9 0.76 8.7 0.0 4.7 1 1 5 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KFM27823.1 - 0.0039 16.6 0.0 3.6 6.8 0.0 2.9 2 1 0 3 3 3 2 WD40-like domain DUF5046 PF16465.5 KFM27823.1 - 0.032 13.7 0.9 2.8 7.3 0.8 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF5046) PQQ PF01011.21 KFM27823.1 - 0.11 12.5 0.0 5.7 7.1 0.0 3.0 3 0 0 3 3 3 0 PQQ enzyme repeat GDA1_CD39 PF01150.17 KFM27824.1 - 5.4e-79 265.8 0.0 9.4e-63 212.3 0.0 2.0 1 1 1 2 2 2 2 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 KFM27824.1 - 0.044 13.2 0.0 0.072 12.5 0.0 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family TPT PF03151.16 KFM27825.1 - 1e-17 64.5 13.6 1.2e-17 64.2 13.6 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KFM27825.1 - 7.3e-17 61.8 23.9 1.1e-08 35.4 11.3 2.4 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KFM27825.1 - 1.9e-06 27.3 13.3 2.3e-06 27.0 12.6 1.3 1 1 0 1 1 1 1 UAA transporter family TFIIF_beta PF02270.15 KFM27828.1 - 1.8e-18 66.4 0.7 3.6e-18 65.5 0.7 1.5 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 KFM27828.1 - 2.2e-12 47.8 0.0 7.8e-12 46.0 0.0 1.8 2 0 0 2 2 2 1 TFIIF, beta subunit N-terminus Tau95 PF09734.9 KFM27828.1 - 8.2e-07 29.9 0.5 1.6e-06 29.0 0.2 1.6 2 0 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Voltage_CLC PF00654.20 KFM27830.1 - 2.1e-51 175.3 24.0 5.3e-33 114.7 16.8 2.4 1 1 1 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 KFM27830.1 - 1.6e-10 41.2 0.0 1.9e-05 25.0 0.0 2.6 2 0 0 2 2 2 2 CBS domain DUF1656 PF07869.12 KFM27830.1 - 1.6 8.8 8.4 4.2 7.5 1.1 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1656) GFO_IDH_MocA PF01408.22 KFM27832.1 - 7.1e-16 59.1 0.6 1.2e-15 58.3 0.6 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold HMA PF00403.26 KFM27832.1 - 0.13 12.7 0.1 2.6 8.6 0.1 2.9 3 0 0 3 3 3 0 Heavy-metal-associated domain Semialdhyde_dh PF01118.24 KFM27832.1 - 0.23 11.9 1.0 0.34 11.3 0.1 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain CTP_transf_like PF01467.26 KFM27833.1 - 3.9e-05 23.9 0.0 0.00032 20.9 0.0 1.9 2 0 0 2 2 2 1 Cytidylyltransferase-like FAD_syn PF06574.12 KFM27833.1 - 0.13 12.1 0.1 0.21 11.5 0.1 1.3 1 0 0 1 1 1 0 FAD synthetase Hat1_N PF10394.9 KFM27834.1 - 4.5e-17 62.7 0.0 7.5e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 KFM27834.1 - 1.1e-06 28.9 0.0 2.4e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFM27834.1 - 0.00015 21.7 0.0 0.0003 20.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFM27834.1 - 0.0006 20.2 0.0 0.0013 19.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4726 PF15855.5 KFM27834.1 - 0.0048 17.1 0.6 0.017 15.3 0.6 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4726) Acetyltransf_CG PF14542.6 KFM27834.1 - 0.0086 16.2 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Kin17_mid PF10357.9 KFM27836.1 - 4.7e-44 149.3 0.6 9.1e-44 148.4 0.6 1.5 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein KN17_SH3 PF18131.1 KFM27836.1 - 8.3e-12 45.0 0.4 1.7e-11 44.0 0.4 1.5 1 0 0 1 1 1 1 KN17 SH3-like C-terminal domain zf-met PF12874.7 KFM27836.1 - 0.0016 18.7 3.9 0.005 17.2 3.9 1.9 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFM27836.1 - 0.0026 18.0 2.0 0.007 16.6 2.0 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFM27836.1 - 3 8.3 5.1 1.5 9.2 1.8 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) DHO_dh PF01180.21 KFM27837.1 - 7.5e-28 97.6 0.0 8.8e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Dus PF01207.17 KFM27837.1 - 0.00056 19.1 0.0 0.00082 18.6 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) GCV_T_C PF08669.11 KFM27837.1 - 0.022 14.6 0.1 0.048 13.6 0.1 1.5 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain Pkinase_Tyr PF07714.17 KFM27838.1 - 3.3e-35 121.6 0.0 6e-35 120.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM27838.1 - 1.2e-30 106.7 0.0 1.8e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KFM27838.1 - 0.00027 19.9 0.0 0.002 17.0 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KFM27838.1 - 0.033 13.6 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Galactosyl_T PF01762.21 KFM27839.1 - 9.3e-28 97.4 0.1 1.2e-27 97.0 0.1 1.1 1 0 0 1 1 1 1 Galactosyltransferase GSH_synth_ATP PF03917.17 KFM27840.1 - 1.7e-97 326.6 0.0 3.4e-80 269.6 0.0 2.0 1 1 1 2 2 2 2 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 KFM27840.1 - 4.4e-31 107.4 0.0 6.3e-31 106.9 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic glutathione synthase TPR_2 PF07719.17 KFM27841.1 - 2.5e-05 24.1 4.6 0.025 14.7 0.3 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat DnaJ PF00226.31 KFM27841.1 - 7.3e-05 22.8 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain TPR_11 PF13414.6 KFM27841.1 - 0.0058 16.3 0.2 0.47 10.2 0.0 2.7 2 0 0 2 2 2 1 TPR repeat TPR_4 PF07721.14 KFM27841.1 - 0.025 15.2 2.0 0.025 15.2 2.0 7.3 8 1 1 9 9 9 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFM27841.1 - 0.075 13.7 40.0 0.23 12.2 1.9 4.8 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFM27841.1 - 0.097 13.1 0.2 12 6.6 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFM27841.1 - 0.34 11.9 0.2 0.34 11.9 0.2 5.5 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFM27841.1 - 2.4 8.8 15.2 77 3.9 9.8 4.0 2 1 2 4 4 4 0 Tetratricopeptide repeat GST_N_3 PF13417.6 KFM27842.1 - 2.9e-11 43.6 0.0 6.3e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KFM27842.1 - 3.3e-09 36.9 0.0 5.5e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KFM27842.1 - 7.9e-08 32.5 0.0 3.3e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFM27842.1 - 1.1e-06 28.6 0.6 2.7e-06 27.3 0.6 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFM27842.1 - 4e-06 27.0 0.0 7e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFM27842.1 - 0.00013 22.1 0.0 0.00026 21.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF1707 PF08044.11 KFM27842.1 - 0.11 12.5 0.1 0.29 11.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1707) Beach PF02138.18 KFM27843.1 - 1.6e-101 339.3 0.0 2.1e-101 338.9 0.0 1.1 1 0 0 1 1 1 1 Beige/BEACH domain GST_N_3 PF13417.6 KFM27843.1 - 4.6e-08 33.4 0.1 1e-07 32.2 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KFM27843.1 - 1.4e-06 28.5 0.0 3.7e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFM27843.1 - 2.2e-06 27.6 0.5 1.1e-05 25.3 0.1 2.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KFM27843.1 - 0.00025 21.3 0.0 0.00065 20.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFM27843.1 - 0.0011 19.1 0.0 0.0026 17.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFM27843.1 - 0.0016 18.6 0.0 0.0037 17.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF2710 PF10921.8 KFM27843.1 - 0.056 13.9 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2710) PQQ_3 PF13570.6 KFM27843.1 - 6.9 7.3 14.3 39 4.9 0.0 5.2 5 0 0 5 5 5 0 PQQ-like domain V-SNARE_C PF12352.8 KFM27844.1 - 1.9e-09 37.7 1.9 0.00074 19.7 0.1 2.4 2 0 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KFM27844.1 - 0.00011 22.0 0.1 0.0019 18.1 0.0 2.3 2 0 0 2 2 2 1 Sec20 DUF5089 PF17002.5 KFM27844.1 - 0.00039 20.4 7.1 0.0012 18.7 0.8 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF5089) Laminin_II PF06009.12 KFM27844.1 - 0.017 15.2 1.7 1.1 9.2 0.2 2.3 2 0 0 2 2 2 0 Laminin Domain II Spc29 PF17082.5 KFM27844.1 - 0.059 13.2 1.2 0.94 9.3 0.1 2.1 2 0 0 2 2 2 0 Spindle Pole Component 29 SlyX PF04102.12 KFM27844.1 - 0.09 13.4 1.9 7.4 7.3 0.1 2.9 2 1 0 2 2 2 0 SlyX DUF4200 PF13863.6 KFM27844.1 - 0.17 12.3 3.2 1.4 9.4 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) KxDL PF10241.9 KFM27844.1 - 0.22 11.8 2.8 0.38 11.1 0.7 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein DUF1664 PF07889.12 KFM27844.1 - 0.49 10.4 3.5 8.1 6.5 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) HIP1_clath_bdg PF16515.5 KFM27844.1 - 8.3 7.1 9.8 1.5 9.5 0.6 2.8 3 1 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SBP PF03110.14 KFM27845.1 - 1.5e-27 95.7 8.5 2.5e-27 95.0 8.5 1.4 1 0 0 1 1 1 1 SBP domain ubiquitin PF00240.23 KFM27846.1 - 1.2e-07 31.4 0.0 1.6e-05 24.5 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD_2 PF13881.6 KFM27846.1 - 0.00023 21.3 0.0 0.00031 20.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Raptor_N PF14538.6 KFM27847.1 - 1.2e-66 223.2 0.0 1.8e-66 222.6 0.0 1.3 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 KFM27847.1 - 6.5e-06 26.8 0.2 0.013 16.3 0.0 3.3 2 0 0 2 2 2 2 WD domain, G-beta repeat HEAT PF02985.22 KFM27847.1 - 2e-05 24.5 6.4 0.0063 16.7 0.1 5.4 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.6 KFM27847.1 - 0.0021 18.4 2.8 0.16 12.4 1.0 4.0 2 1 0 2 2 2 1 HEAT repeats DUF1028 PF06267.12 KFM27847.1 - 0.043 13.6 0.8 0.082 12.7 0.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF1028) HEAT_EZ PF13513.6 KFM27847.1 - 0.71 10.4 13.9 0.053 14.0 2.4 3.9 3 1 0 3 3 3 0 HEAT-like repeat SPG48 PF14764.6 KFM27848.1 - 0.006 17.0 0.1 0.014 15.9 0.0 1.6 2 0 0 2 2 2 1 AP-5 complex subunit, vesicle trafficking TPR_14 PF13428.6 KFM27848.1 - 2 9.5 6.5 3.1 8.9 0.1 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat Ferrochelatase PF00762.19 KFM27851.1 - 8.7e-96 320.7 0.0 4.2e-95 318.5 0.0 1.8 1 1 0 1 1 1 1 Ferrochelatase Chloroa_b-bind PF00504.21 KFM27851.1 - 0.00045 20.8 0.0 0.00093 19.8 0.0 1.5 1 0 0 1 1 1 1 Chlorophyll A-B binding protein CbiX PF01903.17 KFM27851.1 - 0.05 13.9 0.1 2.8 8.3 0.0 2.6 3 0 0 3 3 3 0 CbiX SNF2_N PF00176.23 KFM27853.1 - 2.3e-39 135.1 0.0 4.6e-21 74.9 0.0 2.1 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KFM27853.1 - 3e-11 43.6 0.0 4.6e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM27853.1 - 0.0039 17.2 0.0 0.0057 16.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFM27853.1 - 0.031 14.1 0.0 0.082 12.7 0.0 1.6 2 0 0 2 2 2 0 DEAD/DEAH box helicase HDA2-3 PF11496.8 KFM27853.1 - 0.074 12.2 0.0 0.41 9.8 0.0 1.8 2 0 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 DUF2439 PF10382.9 KFM27854.1 - 1.4e-05 25.3 0.0 1.9e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) RAB3GAP2_N PF14655.6 KFM27855.1 - 9.4e-26 91.0 0.0 3.8e-17 62.7 0.0 2.1 2 0 0 2 2 2 2 Rab3 GTPase-activating protein regulatory subunit N-terminus zf-CHY PF05495.12 KFM27856.1 - 1.2e-10 41.7 8.4 1.2e-10 41.7 8.4 3.6 2 1 0 2 2 2 1 CHY zinc finger zinc_ribbon_6 PF14599.6 KFM27856.1 - 6.7e-08 32.4 0.0 6.7e-08 32.4 0.0 4.1 4 2 0 4 4 4 1 Zinc-ribbon Rad50_zn_hook PF04423.14 KFM27856.1 - 0.044 13.6 4.2 0.12 12.2 0.9 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif NuA4 PF09340.10 KFM27857.1 - 2.8e-18 65.5 0.2 4e-18 65.1 0.2 1.2 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 GAS PF13851.6 KFM27858.1 - 0.58 9.5 2.4 26 4.1 0.1 2.7 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Filament PF00038.21 KFM27858.1 - 1.1 8.7 5.7 1.1 8.8 0.1 2.6 3 0 0 3 3 3 0 Intermediate filament protein Cornichon PF03311.14 KFM27859.1 - 1.4e-28 99.7 4.2 1.8e-28 99.3 4.2 1.1 1 0 0 1 1 1 1 Cornichon protein tRNA-synt_2 PF00152.20 KFM27860.1 - 4.8e-74 249.3 0.0 1.5e-61 208.2 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KFM27860.1 - 2.3e-06 27.5 0.0 5.1e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain WHEP-TRS PF00458.20 KFM27860.1 - 8.8e-05 22.6 8.1 0.00028 21.0 8.1 1.9 1 0 0 1 1 1 1 WHEP-TRS domain tRNA-synt_2d PF01409.20 KFM27860.1 - 0.0099 15.4 0.0 0.094 12.2 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) Aldedh PF00171.22 KFM27861.1 - 5.6e-120 401.0 0.2 6.8e-120 400.7 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DnaJ PF00226.31 KFM27862.1 - 7.6e-05 22.8 0.0 0.00012 22.1 0.0 1.3 1 1 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 KFM27862.1 - 0.0035 17.4 0.0 0.004 17.1 0.0 1.1 1 0 0 1 1 1 1 Pam16 Nicastrin PF05450.15 KFM27863.1 - 1.9e-13 50.4 0.0 3.1e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Nicastrin Ncstrn_small PF18266.1 KFM27863.1 - 9.3e-10 38.8 0.0 1.4e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Nicastrin small lobe Peptidase_M28 PF04389.17 KFM27863.1 - 0.00029 20.6 0.2 0.0006 19.6 0.1 1.5 2 0 0 2 2 2 1 Peptidase family M28 DUF1279 PF06916.13 KFM27864.1 - 9.5e-22 77.4 0.1 1.4e-21 76.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) DUF5464 PF17552.2 KFM27864.1 - 0.22 11.8 0.5 0.22 11.8 0.5 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5464) HSA PF07529.13 KFM27865.1 - 4.9e-05 23.6 0.0 4.9e-05 23.6 0.0 2.4 3 0 0 3 3 3 1 HSA Myb_DNA-bind_6 PF13921.6 KFM27865.1 - 0.00027 21.1 0.0 0.00052 20.2 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KFM27865.1 - 0.0011 19.2 0.0 0.0026 17.9 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Transket_pyr PF02779.24 KFM27866.1 - 9.2e-68 227.4 0.0 1.5e-67 226.7 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 KFM27866.1 - 1.2e-65 221.4 0.0 2e-65 220.7 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 KFM27866.1 - 1.8e-47 160.8 0.0 3.3e-47 160.0 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 KFM27866.1 - 8.3e-15 54.1 1.2 1.1e-14 53.8 0.1 1.9 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus RELT PF12606.8 KFM27869.1 - 0.032 13.2 1.3 0.036 13.1 0.1 1.7 2 0 0 2 2 2 0 Tumour necrosis factor receptor superfamily member 19 DUF1418 PF07214.12 KFM27869.1 - 1.1 9.2 5.3 0.29 11.0 0.6 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1418) Pentapeptide_2 PF01469.18 KFM27870.1 - 0.0061 16.4 14.1 0.0061 16.4 14.1 2.0 1 1 1 2 2 2 2 Pentapeptide repeats (8 copies) Pentapeptide_2 PF01469.18 KFM27871.1 - 7.3e-05 22.6 37.3 0.0013 18.6 11.2 1.9 1 1 1 2 2 2 2 Pentapeptide repeats (8 copies) Mito_carr PF00153.27 KFM27872.1 - 3.4e-40 135.9 7.9 4.1e-22 77.9 0.2 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF3489 PF11994.8 KFM27872.1 - 0.13 12.3 0.0 0.39 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3489) Topoisom_I_N PF02919.15 KFM27874.1 - 2.6e-92 308.2 0.6 4.7e-92 307.3 0.6 1.4 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.20 KFM27874.1 - 2.7e-87 291.9 0.6 4.1e-87 291.3 0.6 1.3 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.6 KFM27874.1 - 4.7e-32 109.7 0.2 1e-31 108.6 0.2 1.6 1 0 0 1 1 1 1 C-terminal topoisomerase domain DUF4140 PF13600.6 KFM27874.1 - 0.046 14.2 2.4 1.3 9.5 0.1 3.5 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF4407 PF14362.6 KFM27874.1 - 2 7.7 10.0 0.053 12.9 1.8 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Ras PF00071.22 KFM27875.1 - 1.6e-57 193.6 0.2 2e-57 193.3 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM27875.1 - 1.3e-36 125.5 0.2 1.7e-36 125.0 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM27875.1 - 2.4e-14 53.2 0.1 3e-14 52.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFM27875.1 - 4.1e-05 23.6 0.1 5.8e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KFM27875.1 - 9.3e-05 21.9 0.1 0.00014 21.4 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KFM27875.1 - 0.0001 21.8 0.1 0.00013 21.4 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFM27875.1 - 0.00013 21.5 0.1 0.0005 19.7 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KFM27875.1 - 0.00031 20.3 0.1 0.0058 16.2 0.1 2.3 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KFM27875.1 - 0.00041 20.3 0.0 0.12 12.3 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Pertussis_S1 PF02917.14 KFM27875.1 - 0.026 14.3 0.0 0.036 13.8 0.0 1.2 1 0 0 1 1 1 0 Pertussis toxin, subunit 1 AAA_7 PF12775.7 KFM27875.1 - 0.038 13.5 0.0 0.061 12.8 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 KFM27875.1 - 0.075 12.4 0.0 0.26 10.7 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein TRAPP PF04051.16 KFM27876.1 - 1e-35 122.6 0.0 1.2e-35 122.4 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DAHP_snth_FXD PF18152.1 KFM27876.1 - 0.13 12.1 0.0 2.9 7.8 0.1 2.2 2 0 0 2 2 2 0 DAHP synthase ferredoxin-like domain Metallophos PF00149.28 KFM27877.1 - 7e-13 49.5 0.0 1.2e-12 48.7 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFM27877.1 - 2.8e-07 30.9 0.0 4.6e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 KFM27877.1 - 0.033 13.5 0.0 0.045 13.1 0.0 1.1 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily EamA PF00892.20 KFM27878.1 - 5.4e-24 84.9 21.0 2.7e-13 50.3 6.6 2.4 2 0 0 2 2 2 2 EamA-like transporter family Aa_trans PF01490.18 KFM27879.1 - 5.2e-33 114.3 8.5 4.9e-30 104.6 3.3 2.1 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein TetR_C_12 PF16914.5 KFM27879.1 - 0.11 12.7 0.2 0.49 10.6 0.1 2.0 2 0 0 2 2 2 0 Bacterial transcriptional repressor C-terminal Aa_trans PF01490.18 KFM27880.1 - 8.2e-83 278.4 41.2 1.9e-60 204.7 26.7 3.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KFM27880.1 - 2.3e-07 30.2 20.3 0.00014 21.1 6.6 2.6 2 0 0 2 2 2 2 Tryptophan/tyrosine permease family Aa_trans PF01490.18 KFM27881.1 - 5.8e-79 265.7 27.1 6.5e-79 265.5 27.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein VCH_CASS14 PF18315.1 KFM27881.1 - 0.0019 18.2 0.0 0.0059 16.6 0.0 1.8 2 0 0 2 2 2 1 Integron cassette protein VCH_CASS1 chain DUF2651 PF10852.8 KFM27881.1 - 0.12 13.0 0.4 0.12 13.0 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2651) RNase_PH PF01138.21 KFM27882.1 - 1.6e-37 129.0 0.6 5e-37 127.4 0.5 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KFM27882.1 - 8.5e-07 28.9 0.1 1.8e-06 27.9 0.1 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 TPR_9 PF13371.6 KFM27883.1 - 9.4e-06 25.7 2.5 9.4e-06 25.7 2.5 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFM27883.1 - 2.6e-05 24.0 6.9 7.7e-05 22.5 0.2 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFM27883.1 - 4e-05 23.3 0.1 0.00047 19.9 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFM27883.1 - 0.00014 22.4 17.0 0.0037 18.0 1.3 3.9 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFM27883.1 - 0.0016 19.1 17.7 0.13 12.9 3.1 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFM27883.1 - 0.01 16.0 0.1 1.3 9.4 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_15 PF13429.6 KFM27883.1 - 0.029 13.6 0.1 0.081 12.1 0.0 1.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFM27883.1 - 0.081 13.5 7.1 1.2 9.7 0.8 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFM27883.1 - 0.12 12.7 0.7 0.12 12.7 0.7 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat ATG16 PF08614.11 KFM27884.1 - 0.018 15.3 4.5 0.025 14.8 4.5 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Med28 PF11594.8 KFM27884.1 - 0.095 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 28 Hydantoinase_B PF02538.14 KFM27884.1 - 0.1 11.0 0.7 6.1 5.1 0.2 2.0 1 1 1 2 2 2 0 Hydantoinase B/oxoprolinase IF-2 PF11987.8 KFM27886.1 - 2.2e-20 72.8 0.0 5.8e-20 71.4 0.0 1.7 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU PF00009.27 KFM27886.1 - 1.4e-17 63.8 1.6 4.1e-14 52.6 1.9 3.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain IF2_N PF04760.15 KFM27886.1 - 9.9e-09 34.9 0.1 2.8e-08 33.5 0.0 1.9 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.23 KFM27886.1 - 5.7e-07 29.6 0.0 1.1e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 KFM27886.1 - 0.00036 20.4 0.1 0.28 11.1 0.0 2.9 3 0 0 3 3 3 2 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.25 KFM27886.1 - 0.0014 19.0 0.2 0.2 12.1 0.1 2.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Ras PF00071.22 KFM27886.1 - 0.011 15.3 0.0 0.033 13.8 0.0 1.7 2 0 0 2 2 2 0 Ras family Roc PF08477.13 KFM27886.1 - 0.018 15.3 0.0 0.032 14.4 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 KFM27886.1 - 0.064 12.8 0.0 0.96 9.0 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B SRPRB PF09439.10 KFM27886.1 - 0.071 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Spore_YtfJ PF09579.10 KFM27886.1 - 0.098 12.8 0.0 0.33 11.1 0.0 1.9 1 0 0 1 1 1 0 Sporulation protein YtfJ (Spore_YtfJ) Dynamin_N PF00350.23 KFM27886.1 - 0.22 11.6 0.1 1.6 8.8 0.0 2.4 2 1 0 2 2 2 0 Dynamin family CLP_protease PF00574.23 KFM27887.1 - 2.6e-61 206.7 0.0 3.1e-61 206.4 0.0 1.0 1 0 0 1 1 1 1 Clp protease Cullin PF00888.22 KFM27888.1 - 1.1e-142 476.8 0.0 3e-108 363.1 0.0 2.1 2 0 0 2 2 2 2 Cullin family Cullin_Nedd8 PF10557.9 KFM27888.1 - 1.8e-25 88.7 2.7 3.4e-25 87.9 2.7 1.5 1 0 0 1 1 1 1 Cullin protein neddylation domain TrmB PF01978.19 KFM27888.1 - 0.11 12.4 0.1 9.9 6.1 0.0 2.6 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB DUF3493 PF11998.8 KFM27891.1 - 1.5e-14 53.9 0.9 2.9e-14 53.0 0.9 1.5 1 0 0 1 1 1 1 Low psii accumulation1 / Rep27 TPR_16 PF13432.6 KFM27891.1 - 1.4e-06 28.9 2.4 1.4e-06 28.9 2.4 3.3 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFM27891.1 - 0.00015 22.3 6.0 0.073 13.9 0.1 3.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFM27891.1 - 0.00059 19.8 0.1 0.2 11.9 0.2 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFM27891.1 - 0.001 19.5 0.9 0.0032 17.9 0.9 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFM27891.1 - 0.0018 18.0 0.0 0.31 10.9 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFM27891.1 - 0.002 18.4 0.5 0.0085 16.4 0.5 2.1 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFM27891.1 - 0.015 15.2 0.4 0.015 15.2 0.4 3.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFM27891.1 - 0.015 15.3 0.2 0.96 9.6 0.3 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM27891.1 - 0.016 15.4 0.1 0.058 13.6 0.1 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KFM27891.1 - 0.054 13.7 0.0 1.3 9.4 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-CCCH PF00642.24 KFM27892.1 - 7.7e-12 44.8 11.4 0.00062 19.6 1.5 3.2 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KFM27892.1 - 1.8e-08 35.0 9.7 6e-07 30.1 0.3 2.7 1 1 2 3 3 3 2 Torus domain zf_CCCH_4 PF18345.1 KFM27892.1 - 1.1e-07 31.7 22.0 1.4e-05 24.9 1.3 3.6 4 0 0 4 4 4 2 Zinc finger domain zf-CCCH_3 PF15663.5 KFM27892.1 - 0.00069 19.8 8.4 0.0013 18.9 1.6 2.4 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCCH_4 PF18044.1 KFM27892.1 - 0.0035 17.1 0.3 0.0035 17.1 0.3 3.3 4 0 0 4 4 4 2 CCCH-type zinc finger zf-C3H1 PF10650.9 KFM27892.1 - 0.032 13.9 6.4 0.23 11.2 0.4 3.2 3 0 0 3 3 3 0 Putative zinc-finger domain zf-CCCH_2 PF14608.6 KFM27892.1 - 0.37 11.3 16.6 3.5 8.2 2.8 3.4 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger PAP2 PF01569.21 KFM27894.1 - 7.2e-18 64.7 5.4 7.2e-18 64.7 5.4 2.0 1 1 1 2 2 2 1 PAP2 superfamily DUF1097 PF06496.11 KFM27894.1 - 0.061 13.4 0.2 0.061 13.4 0.2 2.8 4 1 0 4 4 4 0 Protein of unknown function (DUF1097) RseC_MucC PF04246.12 KFM27894.1 - 5.1 7.1 5.8 4.9 7.1 1.1 2.5 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC LRR_8 PF13855.6 KFM27895.1 - 0.097 12.5 0.0 0.32 10.8 0.0 1.8 2 1 0 2 2 2 0 Leucine rich repeat GDP_Man_Dehyd PF16363.5 KFM27897.1 - 2.1e-66 224.6 0.0 2.4e-66 224.4 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KFM27897.1 - 2.4e-54 184.3 0.1 3e-54 184.0 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFM27897.1 - 2.3e-17 62.9 0.0 4.9e-17 61.8 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KFM27897.1 - 1.3e-16 60.6 0.0 2.1e-15 56.6 0.0 2.5 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KFM27897.1 - 1.5e-13 50.5 0.0 2.5e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KFM27897.1 - 2e-09 37.6 0.0 3.9e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KFM27897.1 - 7.9e-08 32.0 0.0 1.9e-07 30.7 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFM27897.1 - 2.8e-06 27.4 0.0 4.6e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 KFM27897.1 - 6.6e-06 25.5 0.1 2.5e-05 23.6 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 KFM27897.1 - 1.9e-05 24.3 0.0 3.5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short_C2 PF13561.6 KFM27897.1 - 0.0076 15.8 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.18 KFM27897.1 - 0.012 15.5 0.0 0.027 14.3 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KFM27897.1 - 0.044 14.3 0.1 0.16 12.6 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 KFM27897.1 - 0.065 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain FtsJ PF01728.19 KFM27898.1 - 7.9e-56 189.0 0.0 1.5e-55 188.1 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 KFM27898.1 - 5.1e-36 124.0 0.3 5.1e-36 124.0 0.3 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3381) Spb1_C PF07780.12 KFM27898.1 - 3.9e-34 118.1 1.8 3.9e-34 118.1 1.8 2.3 2 0 0 2 2 2 1 Spb1 C-terminal domain Cwf_Cwc_15 PF04889.12 KFM27898.1 - 0.012 15.3 5.6 0.012 15.3 5.6 2.8 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein PEARLI-4 PF05278.12 KFM27898.1 - 4.2 6.9 7.2 7.6 6.0 7.2 1.3 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Spb1_C PF07780.12 KFM27899.1 - 6e-38 130.6 20.0 3e-37 128.3 20.0 1.8 1 1 0 1 1 1 1 Spb1 C-terminal domain DUF4398 PF14346.6 KFM27899.1 - 0.0028 18.2 9.5 0.0028 18.2 9.5 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4398) SIMPL PF04402.14 KFM27899.1 - 4.1 7.8 8.0 6.9 7.1 8.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF541) ABC2_membrane PF01061.24 KFM27900.1 - 5.9e-31 107.5 27.9 5.9e-31 107.5 27.9 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 KFM27900.1 - 2.9e-23 82.9 0.0 5e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 KFM27900.1 - 3.1e-09 36.4 19.4 4.6e-09 35.8 19.4 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 KFM27900.1 - 8.2e-06 25.8 0.2 0.018 14.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFM27900.1 - 0.0034 16.9 0.3 0.85 9.0 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 KFM27900.1 - 0.0071 15.9 0.1 0.015 14.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KFM27900.1 - 0.018 15.0 0.2 0.11 12.4 0.1 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 KFM27900.1 - 0.043 14.2 0.0 0.08 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KFM27900.1 - 0.044 13.5 0.1 0.099 12.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF4818 PF16089.5 KFM27900.1 - 0.049 14.1 2.0 0.11 13.0 2.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4818) IstB_IS21 PF01695.17 KFM27900.1 - 0.18 11.6 0.0 0.51 10.1 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein ABC2_membrane_2 PF12679.7 KFM27900.1 - 4.7 6.4 12.8 0.28 10.4 5.4 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein PPR_2 PF13041.6 KFM27901.1 - 2.5e-23 82.0 0.0 5.1e-05 23.4 0.0 7.5 2 2 5 7 7 7 6 PPR repeat family PPR PF01535.20 KFM27901.1 - 3.7e-15 55.0 0.0 0.13 12.5 0.0 6.6 6 0 0 6 6 6 5 PPR repeat PPR_3 PF13812.6 KFM27901.1 - 9.6e-15 54.4 0.0 0.00056 19.9 0.0 4.8 3 2 1 4 4 4 3 Pentatricopeptide repeat domain PPR_long PF17177.4 KFM27901.1 - 9.6e-08 31.6 0.0 0.00076 18.9 0.0 3.0 1 1 2 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 KFM27901.1 - 2.7e-06 27.0 0.0 0.19 11.5 0.0 5.3 5 1 0 5 5 5 2 PPR repeat DUF4096 PF13340.6 KFM27901.1 - 0.12 12.6 2.2 0.58 10.4 0.4 3.0 2 1 1 3 3 3 0 Putative transposase of IS4/5 family (DUF4096) TPR_7 PF13176.6 KFM27901.1 - 0.28 11.3 2.5 3.1 8.1 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat PEMT PF04191.13 KFM27902.1 - 9e-13 48.6 2.8 9e-13 48.6 2.8 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 KFM27902.1 - 0.0051 17.2 0.5 0.011 16.1 0.5 1.7 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ApoL PF05461.11 KFM27902.1 - 0.28 10.5 0.2 0.41 9.9 0.2 1.1 1 0 0 1 1 1 0 Apolipoprotein L Sulfate_transp PF00916.20 KFM27903.1 - 1.5e-14 53.6 24.2 1.5e-14 53.6 24.2 2.0 1 1 1 2 2 2 1 Sulfate permease family STAS PF01740.21 KFM27903.1 - 6.1e-06 25.9 0.0 1.4e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 STAS domain cNMP_binding PF00027.29 KFM27903.1 - 9.3e-05 22.4 0.0 0.00044 20.3 0.0 2.1 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain Cyclin PF08613.11 KFM27904.1 - 1.4e-27 97.0 0.0 1.8e-27 96.7 0.0 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KFM27904.1 - 3.9e-08 33.1 0.0 6e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Abhydrolase_6 PF12697.7 KFM27905.1 - 1.1e-22 81.7 14.5 1.8e-22 81.0 14.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFM27905.1 - 1.6e-19 70.6 0.1 3e-11 43.4 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFM27905.1 - 5.9e-19 68.3 0.2 8e-19 67.8 0.2 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 KFM27905.1 - 0.00045 20.0 0.0 0.063 13.0 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.20 KFM27905.1 - 0.00061 20.0 0.3 0.0014 18.8 0.1 1.7 2 0 0 2 2 2 1 Thioesterase domain UPF0227 PF05728.12 KFM27905.1 - 0.0012 18.9 0.0 0.1 12.6 0.0 2.9 2 1 0 2 2 2 1 Uncharacterised protein family (UPF0227) Ndr PF03096.14 KFM27905.1 - 0.0016 17.2 0.0 0.018 13.7 0.0 2.0 2 0 0 2 2 2 1 Ndr family Abhydrolase_4 PF08386.10 KFM27905.1 - 0.013 15.6 0.0 0.03 14.4 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein DUF3530 PF12048.8 KFM27905.1 - 0.048 13.1 0.0 0.068 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) BAAT_C PF08840.11 KFM27905.1 - 0.15 12.0 0.0 0.68 9.8 0.0 1.9 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF979 PF06166.12 KFM27905.1 - 0.18 11.0 0.0 0.27 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF979) SMC_N PF02463.19 KFM27906.1 - 8.4e-46 156.2 0.0 4e-45 153.9 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KFM27906.1 - 3.7e-27 94.9 0.0 9.2e-27 93.7 0.0 1.7 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KFM27906.1 - 2.8e-09 37.2 0.0 5.5e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KFM27906.1 - 0.0018 18.0 0.0 0.0038 17.0 0.0 1.5 2 0 0 2 2 2 1 AAA ATPase domain PI3K_P85_iSH2 PF16454.5 KFM27906.1 - 4.2 7.0 14.4 0.56 9.8 1.0 3.9 4 1 1 5 5 5 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Ribosomal_L24e PF01246.20 KFM27907.1 - 2.3e-32 111.0 4.8 4.1e-32 110.2 4.8 1.4 1 0 0 1 1 1 1 Ribosomal protein L24e zf-FCS PF06467.14 KFM27907.1 - 0.093 12.7 7.7 0.17 11.9 7.3 1.7 1 1 1 2 2 2 0 MYM-type Zinc finger with FCS sequence motif COX16 PF14138.6 KFM27907.1 - 1.5 9.4 5.5 1 9.9 0.2 2.4 2 1 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 DUF4504 PF14953.6 KFM27908.1 - 6.1e-15 55.3 0.0 8.8e-10 38.4 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4504) GCN5L1 PF06320.13 KFM27908.1 - 0.0087 16.2 0.1 0.017 15.2 0.1 1.4 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) MatC_N PF07158.11 KFM27908.1 - 0.11 12.5 0.4 0.2 11.7 0.4 1.3 1 0 0 1 1 1 0 Dicarboxylate carrier protein MatC N-terminus AAA_13 PF13166.6 KFM27908.1 - 0.21 10.2 0.0 0.27 9.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain Syja_N PF02383.18 KFM27909.1 - 7.7e-59 199.6 0.0 9.6e-59 199.3 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain DUF155 PF02582.14 KFM27910.1 - 8.8e-45 152.9 0.0 1.1e-44 152.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 MDMPI_N PF11716.8 KFM27912.1 - 0.017 15.8 9.8 0.017 15.8 9.8 2.1 1 1 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain PhoD PF09423.10 KFM27913.1 - 1.1e-86 291.0 0.0 1.4e-86 290.7 0.0 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 KFM27913.1 - 9.1e-25 87.0 0.0 2e-24 86.0 0.0 1.6 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 KFM27913.1 - 0.00018 22.0 0.0 0.00043 20.8 0.0 1.6 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain V-SNARE_C PF12352.8 KFM27914.1 - 2.6e-17 62.8 11.8 8.5e-09 35.6 0.7 3.6 2 1 2 4 4 4 2 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 KFM27914.1 - 1.9e-16 60.2 3.6 2.3e-16 59.9 2.0 2.0 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.13 KFM27914.1 - 0.00066 19.5 0.0 0.0034 17.2 0.0 2.2 1 1 1 2 2 2 1 Sec20 Ribosomal_L5 PF00281.19 KFM27914.1 - 0.27 11.6 1.2 0.67 10.3 0.2 2.1 2 0 0 2 2 2 0 Ribosomal protein L5 Cupin_8 PF13621.6 KFM27915.1 - 7e-24 84.9 0.0 1e-23 84.3 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KFM27915.1 - 0.0014 18.2 0.0 0.0023 17.5 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.11 KFM27915.1 - 0.0027 17.4 0.0 0.0081 15.9 0.0 1.7 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.19 KFM27915.1 - 0.056 13.3 0.1 0.15 11.9 0.1 1.9 1 1 0 1 1 1 0 AraC-like ligand binding domain JmjC PF02373.22 KFM27915.1 - 0.11 12.9 0.0 0.18 12.3 0.0 1.3 1 0 0 1 1 1 0 JmjC domain, hydroxylase dCMP_cyt_deam_1 PF00383.23 KFM27916.1 - 0.0015 18.4 0.0 0.008 16.0 0.0 2.1 2 1 1 3 3 3 1 Cytidine and deoxycytidylate deaminase zinc-binding region KH_1 PF00013.29 KFM27917.1 - 8.6e-34 115.2 0.6 1.5e-15 56.8 0.1 2.3 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 KFM27917.1 - 7.7e-14 51.3 0.0 1.9e-05 24.4 0.0 2.5 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 KFM27917.1 - 1.2e-08 34.6 0.7 0.006 16.4 0.1 2.2 2 0 0 2 2 2 2 KH domain MOEP19 PF16005.5 KFM27917.1 - 2.2e-06 27.6 0.0 0.1 12.6 0.0 2.3 2 0 0 2 2 2 2 KH-like RNA-binding domain Myotoxins PF00819.17 KFM27917.1 - 0.033 14.4 0.4 17 5.8 0.1 2.7 2 0 0 2 2 2 0 Myotoxin, crotamine NPAT_C PF15712.5 KFM27917.1 - 0.14 10.7 0.5 0.21 10.2 0.5 1.1 1 0 0 1 1 1 0 NPAT C terminus UPF0086 PF01868.16 KFM27917.1 - 0.17 11.8 0.0 29 4.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function UPF0086 RCDG1 PF15725.5 KFM27917.1 - 3.2 8.2 12.0 5.1 7.6 0.2 3.6 3 0 0 3 3 3 0 Renal cancer differentiation gene 1 protein CP12 PF02672.15 KFM27918.1 - 1.3e-23 83.5 5.1 1.7e-23 83.1 5.1 1.1 1 0 0 1 1 1 1 CP12 domain TPR_1 PF00515.28 KFM27919.1 - 2.3e-16 58.8 11.7 1.3e-07 31.1 0.3 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFM27919.1 - 2.1e-14 52.4 18.2 1.1e-06 28.3 0.4 4.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFM27919.1 - 3.1e-13 50.1 6.5 6.4e-09 36.3 4.9 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFM27919.1 - 2.9e-12 46.7 10.9 8.7e-07 29.1 0.3 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFM27919.1 - 3.9e-10 39.2 11.7 1.5e-09 37.4 2.1 4.0 2 2 2 4 4 4 1 TPR repeat TPR_14 PF13428.6 KFM27919.1 - 1.4e-08 34.9 7.9 0.0025 18.5 0.3 4.1 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFM27919.1 - 1.7e-08 34.0 8.6 0.011 15.9 0.4 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFM27919.1 - 4.7e-08 32.5 3.2 0.00084 19.2 0.1 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFM27919.1 - 5.3e-06 26.4 6.5 1.7e-05 24.9 0.4 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFM27919.1 - 2.4e-05 24.7 5.9 0.061 14.0 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFM27919.1 - 4.1e-05 23.6 0.5 0.00011 22.3 0.5 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFM27919.1 - 6.1e-05 23.5 3.2 6.1e-05 23.5 3.2 2.1 2 1 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM27919.1 - 0.017 15.4 2.5 0.24 11.6 3.7 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 KFM27919.1 - 0.025 15.0 2.0 0.19 12.2 2.0 2.3 1 1 0 1 1 1 0 Bacterial transcriptional activator domain ChAPs PF09295.10 KFM27919.1 - 0.033 13.2 0.2 0.04 12.9 0.2 1.1 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) GARP PF16731.5 KFM27919.1 - 0.034 13.9 1.3 0.054 13.2 1.3 1.3 1 0 0 1 1 1 0 Glutamic acid/alanine-rich protein of Trypanosoma FAT PF02259.23 KFM27919.1 - 0.044 13.0 5.3 0.092 11.9 4.8 1.4 1 1 0 2 2 2 0 FAT domain Fis1_TPR_C PF14853.6 KFM27919.1 - 0.065 13.3 0.5 2.2 8.4 0.1 2.4 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Lambda_Kil PF06301.11 KFM27919.1 - 0.082 12.5 3.0 1.6 8.4 0.1 2.4 2 0 0 2 2 2 0 Bacteriophage lambda Kil protein RPN7 PF10602.9 KFM27919.1 - 0.13 12.0 1.2 6.4 6.4 0.2 2.3 1 1 1 2 2 2 0 26S proteasome subunit RPN7 MIT PF04212.18 KFM27919.1 - 1.1 9.3 6.7 13 6.0 0.6 3.2 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 KFM27919.1 - 2 8.4 10.5 3.1 7.8 0.6 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Ribosomal_L28e PF01778.17 KFM27920.1 - 5.8e-39 133.4 1.4 5.8e-39 133.4 1.4 1.9 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 KFM27920.1 - 1.2e-17 64.3 2.9 2.4e-17 63.4 2.9 1.4 1 0 0 1 1 1 1 Mak16 protein C-terminal region Not1 PF04054.15 KFM27920.1 - 0.0038 16.2 0.0 0.0053 15.7 0.0 1.2 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 MIP PF00230.20 KFM27921.1 - 1.1e-22 80.9 6.8 8.2e-11 42.0 1.5 2.2 2 0 0 2 2 2 2 Major intrinsic protein MIP PF00230.20 KFM27923.1 - 3.7e-24 85.7 7.9 7.9e-14 51.9 2.4 2.2 2 0 0 2 2 2 2 Major intrinsic protein MIP PF00230.20 KFM27924.1 - 5.2e-20 72.1 3.8 1.6e-19 70.5 3.8 1.7 1 1 0 1 1 1 1 Major intrinsic protein MtrG PF04210.13 KFM27924.1 - 8.2 6.4 5.9 16 5.4 5.9 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G MIP PF00230.20 KFM27925.1 - 1.3e-23 83.9 5.7 6.5e-14 52.2 2.4 2.2 2 0 0 2 2 2 2 Major intrinsic protein ECF_trnsprt PF12822.7 KFM27925.1 - 2 8.5 14.7 0.73 9.9 1.4 2.4 2 0 0 2 2 2 0 ECF transporter, substrate-specific component FGGY_N PF00370.21 KFM27926.1 - 1.4e-66 224.6 0.0 1.8e-66 224.2 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KFM27926.1 - 6.6e-64 215.3 3.3 1.5e-63 214.1 3.3 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain MIP PF00230.20 KFM27927.1 - 5.7e-23 81.8 6.0 8.6e-11 42.0 1.7 2.1 2 0 0 2 2 2 2 Major intrinsic protein Methyltransf_25 PF13649.6 KFM27928.1 - 8.2e-11 42.5 0.0 1.5e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFM27928.1 - 3.4e-08 34.0 0.0 5.8e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM27928.1 - 3.7e-07 30.8 0.0 5.6e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM27928.1 - 4e-07 29.9 0.0 6.5e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM27928.1 - 9.5e-06 25.5 0.0 1.4e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 KFM27928.1 - 0.00071 19.3 0.0 0.001 18.8 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Ubie_methyltran PF01209.18 KFM27928.1 - 0.00082 18.8 0.0 0.0011 18.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KFM27928.1 - 0.017 14.6 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase PCMT PF01135.19 KFM27929.1 - 2.9e-46 157.9 0.1 3.6e-46 157.6 0.1 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KFM27929.1 - 1.1e-06 28.5 0.0 2.3e-06 27.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KFM27929.1 - 0.00021 21.3 0.0 0.00032 20.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFM27929.1 - 0.0004 21.0 0.0 0.0017 19.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM27929.1 - 0.00059 20.5 0.0 0.00094 19.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM27929.1 - 0.0058 16.5 0.0 0.012 15.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFM27929.1 - 0.023 14.2 0.1 0.052 13.1 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Cupin_3 PF05899.12 KFM27929.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) PTPlike_phytase PF14566.6 KFM27931.1 - 2.1e-104 346.3 0.0 3.2e-53 180.0 0.0 3.8 3 1 0 3 3 3 3 Inositol hexakisphosphate TIM PF00121.18 KFM27931.1 - 1.1e-83 280.3 0.0 1.5e-83 279.9 0.0 1.2 1 0 0 1 1 1 1 Triosephosphate isomerase 2-Hacid_dh_C PF02826.19 KFM27932.1 - 2e-37 128.3 0.0 1.9e-20 73.0 0.0 2.2 1 1 1 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFM27932.1 - 1.1e-29 102.7 0.0 1.3e-29 102.6 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain CoA_binding_2 PF13380.6 KFM27932.1 - 0.01 16.3 0.1 0.023 15.2 0.1 1.5 1 0 0 1 1 1 0 CoA binding domain tify PF06200.14 KFM27932.1 - 0.072 12.4 0.0 0.18 11.2 0.0 1.7 1 0 0 1 1 1 0 tify domain ClpS PF02617.17 KFM27933.1 - 7.3e-19 67.3 0.2 8.3e-19 67.2 0.2 1.0 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS YbjN PF10722.9 KFM27933.1 - 0.12 12.4 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 Putative bacterial sensory transduction regulator Peptidase_M24 PF00557.24 KFM27934.1 - 1.4e-21 77.2 1.3 1.9e-21 76.8 1.3 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF768 PF05589.11 KFM27934.1 - 0.059 13.4 1.0 0.18 11.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF768) Herpes_UL56 PF04534.12 KFM27934.1 - 0.064 12.7 0.3 0.11 12.0 0.3 1.3 1 0 0 1 1 1 0 Herpesvirus UL56 protein Yos1 PF08571.10 KFM27935.1 - 6.8e-21 74.3 0.1 7.5e-21 74.2 0.1 1.0 1 0 0 1 1 1 1 Yos1-like AAA_16 PF13191.6 KFM27936.1 - 1e-10 42.2 0.8 3.4e-10 40.6 0.8 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFM27936.1 - 3.9e-08 33.6 0.0 6.7e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KFM27936.1 - 9.1e-07 29.4 0.0 1.6e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KFM27936.1 - 0.0031 17.4 0.0 0.0055 16.6 0.0 1.4 1 1 0 1 1 1 1 NACHT domain ORC4_C PF14629.6 KFM27936.1 - 0.0039 16.6 0.0 0.0063 15.9 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus TniB PF05621.11 KFM27936.1 - 0.0053 16.2 0.0 0.0079 15.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein AAA_14 PF13173.6 KFM27936.1 - 0.028 14.4 0.0 0.2 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain RabGAP-TBC PF00566.18 KFM27937.1 - 6e-36 124.1 0.0 1e-35 123.4 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3040 PF11239.8 KFM27937.1 - 0.088 13.1 1.6 2.1 8.7 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) DUF4844 PF16133.5 KFM27937.1 - 0.16 12.5 0.0 0.28 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) Exo_endo_phos PF03372.23 KFM27938.1 - 2.1e-08 34.0 1.8 5.8e-08 32.5 1.8 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SBP PF03110.14 KFM27939.1 - 1.7e-14 53.9 10.1 2.3e-14 53.5 10.1 1.2 1 0 0 1 1 1 1 SBP domain Sugar_tr PF00083.24 KFM27940.1 - 5.5e-95 318.9 11.8 6.2e-95 318.7 11.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFM27940.1 - 3.8e-25 88.5 50.4 8.9e-25 87.3 46.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CAF1 PF04857.20 KFM27941.1 - 2e-55 188.2 0.0 1.4e-40 139.4 0.0 2.0 2 0 0 2 2 2 2 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.20 KFM27941.1 - 0.057 13.1 0.0 1 9.0 0.0 2.7 4 0 0 4 4 4 0 3'-5' exonuclease RNase_T PF00929.24 KFM27941.1 - 0.21 12.1 0.2 67 4.0 0.0 3.1 3 0 0 3 3 3 0 Exonuclease ABC_tran PF00005.27 KFM27942.1 - 5.9e-26 91.6 0.0 1.9e-25 90.0 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KFM27942.1 - 1e-08 35.4 0.0 0.00033 20.6 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFM27942.1 - 1.1e-05 25.0 0.1 2.4e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 KFM27942.1 - 1.2e-05 24.9 0.0 0.087 12.3 0.0 2.1 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_27 PF13514.6 KFM27942.1 - 3.5e-05 23.5 0.0 5.2e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFM27942.1 - 7.4e-05 23.2 0.3 7.4e-05 23.2 0.3 1.5 2 0 0 2 2 1 1 AAA ATPase domain AAA PF00004.29 KFM27942.1 - 0.00015 22.2 0.0 0.0014 19.1 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KFM27942.1 - 0.00065 19.1 0.1 0.08 12.3 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 KFM27942.1 - 0.00091 19.2 0.1 0.0013 18.6 0.1 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 KFM27942.1 - 0.0041 17.7 0.0 0.006 17.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 KFM27942.1 - 0.0068 16.2 0.0 0.0091 15.7 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KFM27942.1 - 0.011 15.8 0.0 0.027 14.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KFM27942.1 - 0.011 16.0 0.0 0.019 15.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KFM27942.1 - 0.013 15.4 0.0 0.033 14.1 0.0 1.6 2 0 0 2 2 2 0 NACHT domain Rad17 PF03215.15 KFM27942.1 - 0.013 15.4 0.0 0.018 15.0 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_22 PF13401.6 KFM27942.1 - 0.019 15.2 0.0 0.067 13.5 0.0 2.1 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 KFM27942.1 - 0.02 14.1 0.1 0.033 13.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_30 PF13604.6 KFM27942.1 - 0.022 14.5 0.5 0.083 12.6 0.4 2.0 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KFM27942.1 - 0.023 14.3 1.2 0.041 13.4 0.1 2.0 3 0 0 3 3 2 0 AAA domain AAA_33 PF13671.6 KFM27942.1 - 0.041 14.0 0.1 0.047 13.8 0.1 1.4 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KFM27942.1 - 0.047 14.1 0.0 0.071 13.5 0.0 1.3 1 0 0 1 1 1 0 RNA helicase Viral_helicase1 PF01443.18 KFM27942.1 - 0.065 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase MMR_HSR1 PF01926.23 KFM27942.1 - 0.18 11.9 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Adeno_IVa2 PF02456.15 KFM27942.1 - 0.22 10.3 0.0 0.31 9.8 0.0 1.1 1 0 0 1 1 1 0 Adenovirus IVa2 protein DUF2813 PF11398.8 KFM27942.1 - 0.25 10.6 0.0 0.34 10.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) G-alpha PF00503.20 KFM27942.1 - 0.34 10.0 0.0 0.45 9.6 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit SGL PF08450.12 KFM27943.1 - 5.5e-64 216.1 0.3 6.4e-60 202.8 0.1 2.1 2 0 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region PQQ_2 PF13360.6 KFM27943.1 - 3.8e-05 23.4 0.1 0.0025 17.4 0.0 2.3 1 1 0 2 2 2 1 PQQ-like domain WW PF00397.26 KFM27943.1 - 0.00078 19.5 0.1 2.5 8.3 0.0 3.7 3 0 0 3 3 3 1 WW domain NHL PF01436.21 KFM27943.1 - 0.072 13.2 2.5 3.4 7.9 0.0 3.9 4 1 1 5 5 5 0 NHL repeat Phytochelatin PF05023.14 KFM27944.1 - 1.6e-84 282.4 0.0 2e-84 282.1 0.0 1.1 1 0 0 1 1 1 1 Phytochelatin synthase Defensin_2 PF01097.18 KFM27944.1 - 0.03 14.3 0.3 0.06 13.3 0.3 1.5 1 0 0 1 1 1 0 Arthropod defensin Peptidase_C39_2 PF13529.6 KFM27944.1 - 0.14 12.7 0.0 0.44 11.1 0.0 1.7 2 0 0 2 2 2 0 Peptidase_C39 like family DUF1356 PF07092.12 KFM27945.1 - 4e-11 42.6 0.0 5e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) LEA_2 PF03168.13 KFM27945.1 - 0.14 12.7 0.0 0.21 12.1 0.0 1.3 1 0 0 1 1 1 0 Late embryogenesis abundant protein Pentapeptide_2 PF01469.18 KFM27946.1 - 2.4e-09 36.9 97.7 5.3e-05 23.0 28.4 4.2 4 0 0 4 4 4 3 Pentapeptide repeats (8 copies) RHS PF03527.14 KFM27946.1 - 0.12 12.1 0.1 22 4.9 0.0 2.4 2 0 0 2 2 2 0 RHS protein Mito_fiss_reg PF05308.11 KFM27946.1 - 0.68 10.0 1.9 1.5 8.9 1.9 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator Avian_gp85 PF03708.14 KFM27946.1 - 1.4 8.0 7.2 0.066 12.4 1.5 1.6 2 0 0 2 2 2 0 Avian retrovirus envelope protein, gp85 Pentapeptide_2 PF01469.18 KFM27947.1 - 0.0002 21.2 29.0 0.00032 20.5 29.0 1.3 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) MT-A70 PF05063.14 KFM27948.1 - 8e-24 84.5 0.0 1.1e-23 84.0 0.0 1.2 1 0 0 1 1 1 1 MT-A70 HIT PF01230.23 KFM27949.1 - 1.2e-25 90.0 0.0 1.5e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KFM27949.1 - 9.7e-21 74.4 0.0 1.2e-20 74.1 0.0 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Aldo_ket_red PF00248.21 KFM27950.1 - 4.2e-61 206.7 0.0 4.7e-61 206.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family VID27 PF08553.10 KFM27951.1 - 1.9e-45 155.4 0.0 9.2e-45 153.2 0.0 1.8 2 0 0 2 2 2 1 VID27 C-terminal WD40-like domain WD40 PF00400.32 KFM27951.1 - 0.0037 18.1 0.1 0.96 10.4 0.0 3.0 3 0 0 3 3 3 1 WD domain, G-beta repeat UPF0004 PF00919.20 KFM27952.1 - 4e-29 100.5 0.3 7e-29 99.8 0.3 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 KFM27952.1 - 2.9e-18 66.8 0.0 7.3e-18 65.5 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily TRAM_2 PF18693.1 KFM27952.1 - 4.6e-15 55.5 0.5 2.4e-14 53.3 0.2 2.1 2 0 0 2 2 2 1 TRAM domain TRAM PF01938.20 KFM27952.1 - 0.0032 17.4 0.1 0.0099 15.9 0.0 1.8 2 0 0 2 2 2 1 TRAM domain CLP1_P PF16575.5 KFM27952.1 - 0.093 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Dev_Cell_Death PF10539.9 KFM27953.1 - 8.8e-05 22.4 0.0 0.00013 21.9 0.0 1.2 1 0 0 1 1 1 1 Development and cell death domain PEPCK_ATP PF01293.20 KFM27955.1 - 1.1e-84 284.8 0.0 1e-81 275.0 0.0 2.2 1 1 1 2 2 2 2 Phosphoenolpyruvate carboxykinase NIF PF03031.18 KFM27956.1 - 1.9e-11 44.0 0.0 6.3e-08 32.5 0.0 2.2 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase HAD PF12710.7 KFM27956.1 - 0.6 10.5 4.1 1.1 9.7 1.2 2.6 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Got1 PF04178.12 KFM27958.1 - 2e-14 54.0 12.8 2.3e-14 53.8 12.8 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF3040 PF11239.8 KFM27958.1 - 0.041 14.2 0.1 0.041 14.2 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) CPP1-like PF11833.8 KFM27958.1 - 0.23 11.1 4.6 0.26 10.9 4.6 1.2 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF373 PF04123.13 KFM27958.1 - 1.4 8.3 2.9 20 4.5 0.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF373) DUF308 PF03729.13 KFM27958.1 - 1.6 9.1 17.0 1.2 9.5 10.3 2.2 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) PLDc_2 PF13091.6 KFM27959.1 - 5.1e-08 32.9 0.0 0.011 15.6 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KFM27959.1 - 0.88 9.9 2.0 3.9 7.8 0.1 2.7 3 0 0 3 3 3 0 Phospholipase D Active site motif DnaJ PF00226.31 KFM27960.1 - 3.1e-18 65.6 1.2 7.2e-18 64.5 0.1 2.3 3 0 0 3 3 3 1 DnaJ domain Myb_DNA-binding PF00249.31 KFM27960.1 - 1.2e-07 31.7 0.1 1.1e-05 25.5 0.0 2.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFM27960.1 - 0.0072 16.5 0.3 0.054 13.7 0.0 2.6 3 0 0 3 3 3 1 Myb-like DNA-binding domain RRN9 PF10680.9 KFM27960.1 - 9.7 6.6 7.7 0.78 10.1 0.7 2.8 2 1 0 2 2 2 0 RNA polymerase I specific transcription initiation factor 2-oxoacid_dh PF00198.23 KFM27961.1 - 2.5e-54 184.2 0.0 4.9e-42 144.0 0.0 2.1 1 1 1 2 2 2 2 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KFM27961.1 - 6e-14 51.6 0.3 1.4e-13 50.5 0.3 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KFM27961.1 - 2.3e-07 31.0 0.6 6.7e-07 29.5 0.6 1.9 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 KFM27961.1 - 6.6e-06 25.8 0.4 0.00088 19.0 0.0 3.0 3 0 0 3 3 3 1 Biotin-lipoyl like TMPIT PF07851.13 KFM27962.1 - 2.9e-51 174.6 0.1 3.8e-51 174.3 0.1 1.1 1 0 0 1 1 1 1 TMPIT-like protein Oxidored_q3 PF00499.20 KFM27962.1 - 0.047 13.4 0.9 0.61 9.8 0.1 2.2 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 adh_short_C2 PF13561.6 KFM27963.1 - 1.6e-50 171.9 0.9 6.1e-46 156.9 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFM27963.1 - 3e-10 39.9 0.1 4.5e-07 29.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase VCBS PF13517.6 KFM27964.1 - 1.5e-17 63.9 17.1 4.6e-06 27.1 0.4 6.7 5 1 2 7 7 7 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 KFM27964.1 - 1.8e-10 40.7 43.8 0.0065 16.6 0.1 8.7 8 0 0 8 8 8 4 FG-GAP repeat PQQ PF01011.21 KFM27964.1 - 1.2e-05 24.9 2.9 0.36 10.8 0.0 5.4 5 0 0 5 5 5 1 PQQ enzyme repeat PQQ_2 PF13360.6 KFM27964.1 - 1.7e-05 24.5 1.7 0.0001 22.0 2.1 2.1 2 0 0 2 2 2 1 PQQ-like domain Itfg2 PF15907.5 KFM27964.1 - 0.00011 21.3 2.7 8 5.4 0.0 5.2 5 1 1 6 6 6 2 Integrin-alpha FG-GAP repeat-containing protein 2 BBS2_Mid PF14783.6 KFM27964.1 - 0.00053 20.0 4.0 1.4 9.0 0.0 5.5 4 2 1 5 5 5 1 Ciliary BBSome complex subunit 2, middle region TcdB_toxin_midN PF12256.8 KFM27964.1 - 0.011 15.1 5.6 7 6.0 0.0 4.4 4 1 0 4 4 4 0 Insecticide toxin TcdB middle/N-terminal region PliI PF16743.5 KFM27964.1 - 0.031 14.0 1.6 32 4.3 0.1 4.9 5 1 1 6 6 6 0 Periplasmic lysozyme inhibitor of I-type lysozyme PQQ_3 PF13570.6 KFM27964.1 - 0.26 11.8 19.4 3.1 8.4 0.1 6.7 6 1 1 7 7 7 0 PQQ-like domain WD40 PF00400.32 KFM27965.1 - 3.1e-08 34.1 12.4 0.13 13.2 0.1 6.2 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM27965.1 - 1.5e-05 25.2 0.0 4.2 7.7 0.0 4.2 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Lactonase PF10282.9 KFM27965.1 - 0.013 14.8 0.0 0.052 12.8 0.0 1.8 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller PD40 PF07676.12 KFM27965.1 - 0.18 11.8 1.2 23 5.1 0.1 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KFM27965.1 - 0.24 11.3 0.0 9.7 6.0 0.0 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A DnaJ PF00226.31 KFM27966.1 - 4.1e-07 30.0 0.0 8e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain DOMON PF03351.17 KFM27969.1 - 0.037 14.3 0.0 0.057 13.6 0.0 1.4 1 0 0 1 1 1 0 DOMON domain Cytochrom_B561 PF03188.16 KFM27971.1 - 3e-08 33.9 3.6 6.8e-08 32.7 3.6 1.6 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DOMON PF03351.17 KFM27971.1 - 1.9e-07 31.3 0.0 0.023 14.9 0.0 2.5 2 0 0 2 2 2 2 DOMON domain DUF2427 PF10348.9 KFM27971.1 - 0.00073 19.3 0.1 0.0019 17.9 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) DUF420 PF04238.12 KFM27971.1 - 0.019 15.2 1.0 0.085 13.1 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF420) DnaJ PF00226.31 KFM27972.1 - 1.4e-18 66.7 1.7 2.6e-18 65.9 1.7 1.5 1 0 0 1 1 1 1 DnaJ domain Lipase_3 PF01764.25 KFM27972.1 - 6.4e-17 61.7 0.1 1.4e-16 60.7 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) DnaJ_C PF01556.18 KFM27972.1 - 3.3e-11 43.5 0.0 5.5e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain T3SSipB PF16535.5 KFM27972.1 - 0.042 14.3 7.4 0.088 13.3 7.0 1.8 1 1 0 1 1 1 0 Type III cell invasion protein SipB FAST_1 PF06743.15 KFM27974.1 - 8e-30 102.6 0.4 5.2e-05 23.1 0.0 8.5 7 3 2 9 9 9 7 FAST kinase-like protein, subdomain 1 RAP PF08373.10 KFM27974.1 - 5.8e-10 39.1 0.0 2.7e-09 37.0 0.0 2.2 2 0 0 2 2 2 1 RAP domain MTES_1575 PF18741.1 KFM27974.1 - 4.9e-05 23.4 0.0 0.0003 20.9 0.0 2.4 2 0 0 2 2 2 1 REase_MTES_1575 Ras PF00071.22 KFM27975.1 - 4.9e-55 185.6 0.2 5.6e-55 185.3 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFM27975.1 - 5.9e-32 110.4 0.1 8.4e-32 109.9 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFM27975.1 - 6.4e-20 71.3 0.1 6.8e-20 71.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFM27975.1 - 5.4e-06 26.5 0.1 9e-06 25.7 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KFM27975.1 - 6.4e-06 25.7 0.0 8.9e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KFM27975.1 - 2e-05 24.1 0.0 2.6e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFM27975.1 - 0.00032 20.3 0.1 0.00079 19.0 0.1 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFM27975.1 - 0.0016 18.4 0.4 0.95 9.3 0.0 2.3 2 1 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 KFM27975.1 - 0.1 11.7 0.2 2.6 7.1 0.1 2.1 1 1 1 2 2 2 0 G-protein alpha subunit Septin PF00735.18 KFM27975.1 - 0.12 11.7 0.1 0.48 9.6 0.1 1.9 1 1 0 1 1 1 0 Septin AAA_29 PF13555.6 KFM27975.1 - 0.12 12.2 0.0 0.47 10.2 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_2 PF07724.14 KFM27978.1 - 7.3e-39 133.6 0.0 3.3e-37 128.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 KFM27978.1 - 1.5e-15 57.8 0.0 2.1e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFM27978.1 - 1.1e-06 28.6 0.0 4.1e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFM27978.1 - 4.8e-05 23.8 0.3 0.00048 20.6 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KFM27978.1 - 6.2e-05 23.3 0.1 0.00068 19.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain MCM PF00493.23 KFM27978.1 - 6.6e-05 22.1 0.0 0.00011 21.4 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain Mg_chelatase PF01078.21 KFM27978.1 - 0.00012 21.6 0.1 0.006 16.0 0.1 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 KFM27978.1 - 0.00015 21.6 0.0 0.00047 19.9 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 KFM27978.1 - 0.00028 20.6 0.0 0.0044 16.7 0.0 2.5 1 1 0 1 1 1 1 Sigma-54 interaction domain ABC_tran PF00005.27 KFM27978.1 - 0.0011 19.4 0.0 0.0018 18.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter Sigma54_activ_2 PF14532.6 KFM27978.1 - 0.0034 17.5 0.0 0.012 15.7 0.0 1.9 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.6 KFM27978.1 - 0.0038 17.3 0.0 0.0052 16.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KFM27978.1 - 0.0084 15.9 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein NACHT PF05729.12 KFM27978.1 - 0.017 15.0 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 KFM27978.1 - 0.024 14.2 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KFM27978.1 - 0.028 14.1 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KFM27978.1 - 0.031 14.5 0.0 0.061 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KFM27978.1 - 0.036 14.6 0.0 0.056 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 KFM27978.1 - 0.046 13.6 0.0 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KFM27978.1 - 0.047 14.1 0.0 0.073 13.5 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AIRS_C PF02769.22 KFM27978.1 - 0.066 13.3 0.0 0.23 11.6 0.0 1.9 1 1 0 1 1 1 0 AIR synthase related protein, C-terminal domain Rad17 PF03215.15 KFM27978.1 - 0.087 12.7 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_33 PF13671.6 KFM27978.1 - 0.095 12.9 0.1 0.21 11.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain Terminase_6 PF03237.15 KFM27978.1 - 0.13 11.9 0.3 0.96 9.1 0.0 2.0 1 1 1 2 2 2 0 Terminase-like family PhoH PF02562.16 KFM27978.1 - 0.14 11.6 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein ATPase PF06745.13 KFM27978.1 - 0.15 11.4 0.1 0.56 9.5 0.0 1.7 1 1 0 2 2 2 0 KaiC NIF PF03031.18 KFM27980.1 - 2e-52 177.1 0.0 2.5e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DNase-RNase PF02577.14 KFM27981.1 - 1.1e-13 51.0 0.0 1.7e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Bifunctional nuclease UVR PF02151.19 KFM27981.1 - 0.18 11.6 0.2 0.18 11.6 0.2 1.8 2 0 0 2 2 2 0 UvrB/uvrC motif Methyltransf_21 PF05050.12 KFM27982.1 - 6.4e-09 36.1 0.0 9.7e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain SAM_MT PF04445.13 KFM27982.1 - 0.055 12.9 0.0 0.097 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase Methyltransf_21 PF05050.12 KFM27983.1 - 2.4e-06 27.7 0.0 4.2e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain SAM_MT PF04445.13 KFM27983.1 - 0.0095 15.4 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase Smg8_Smg9 PF10220.9 KFM27985.1 - 2.6e-06 26.1 0.0 1.7e-05 23.4 0.0 1.9 2 0 0 2 2 2 2 Smg8_Smg9 MTHFR PF02219.17 KFM27986.1 - 8.7e-114 379.7 0.0 1e-113 379.5 0.0 1.0 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase SWIB PF02201.18 KFM27988.1 - 3e-51 171.2 0.0 9.8e-28 95.9 0.0 2.6 3 0 0 3 3 3 2 SWIB/MDM2 domain DEK_C PF08766.11 KFM27988.1 - 1.7e-14 53.5 1.6 3.5e-14 52.5 1.2 1.8 2 0 0 2 2 2 1 DEK C terminal domain Rrp44_CSD1 PF17216.3 KFM27988.1 - 0.16 11.7 0.1 0.26 11.0 0.1 1.3 1 0 0 1 1 1 0 Rrp44-like cold shock domain HTH_13 PF11972.8 KFM27988.1 - 0.16 12.0 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain DUF1582 PF07621.11 KFM27989.1 - 0.08 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1582) PDZ_3 PF17815.1 KFM27991.1 - 3.3e-33 114.6 0.0 1.1e-32 112.8 0.0 1.8 2 0 0 2 2 2 1 PDZ domain Trypsin_2 PF13365.6 KFM27991.1 - 3.6e-19 70.1 1.8 3.6e-19 70.1 1.8 2.0 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.26 KFM27991.1 - 5.2e-11 42.8 0.2 8.3e-11 42.1 0.2 1.2 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 KFM27991.1 - 7e-07 29.5 0.0 4.9e-06 26.8 0.0 2.4 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 KFM27991.1 - 3.1e-05 23.7 0.1 0.073 12.9 0.1 2.7 2 0 0 2 2 2 2 PDZ domain Imm1 PF14430.6 KFM27991.1 - 0.068 13.8 0.3 19 5.9 0.0 3.5 2 1 1 3 3 3 0 Immunity protein Imm1 PDZ PF00595.24 KFM27991.1 - 0.074 13.4 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 PDZ domain PRC PF05239.16 KFM27992.1 - 1.4e-08 34.7 0.0 4.6e-05 23.4 0.0 2.4 2 0 0 2 2 2 2 PRC-barrel domain Pkinase PF00069.25 KFM27992.1 - 0.00074 19.0 0.0 0.0011 18.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain CLASP_N PF12348.8 KFM27993.1 - 0.00029 20.5 0.8 0.00043 19.9 0.8 1.2 1 0 0 1 1 1 1 CLASP N terminal DUF3646 PF12362.8 KFM27993.1 - 0.56 10.6 4.0 3.7 7.9 1.7 2.6 2 0 0 2 2 2 0 DNA polymerase III gamma and tau subunits C terminal LCAT PF02450.15 KFM27994.1 - 1.1e-11 44.6 0.0 1.6e-10 40.7 0.0 2.0 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase PGAP1 PF07819.13 KFM27994.1 - 0.0046 16.7 0.0 0.094 12.4 0.0 2.1 2 0 0 2 2 2 1 PGAP1-like protein Hydrolase_4 PF12146.8 KFM27994.1 - 0.013 14.8 0.2 0.02 14.2 0.2 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF900 PF05990.12 KFM27994.1 - 0.025 14.1 0.0 0.037 13.6 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Lipase_2 PF01674.18 KFM27994.1 - 0.071 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 2) DUF502 PF04367.13 KFM27995.1 - 3.2e-30 104.1 0.3 6.7e-30 103.1 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF502) SOR_SNZ PF01680.17 KFM27996.1 - 6.8e-94 313.5 9.4 3.9e-84 281.6 5.6 2.3 2 1 1 3 3 3 2 SOR/SNZ family ThiG PF05690.14 KFM27996.1 - 8.7e-10 38.3 7.7 4.1e-07 29.6 0.5 2.3 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 KFM27996.1 - 0.00084 18.5 0.2 0.8 8.7 0.0 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.14 KFM27996.1 - 0.0014 17.9 0.8 0.13 11.5 0.0 2.5 2 1 0 2 2 2 2 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.21 KFM27996.1 - 0.018 14.2 0.2 0.43 9.7 0.0 2.5 2 1 0 2 2 2 0 Indole-3-glycerol phosphate synthase His_biosynth PF00977.21 KFM27996.1 - 0.019 14.4 1.3 0.79 9.1 0.1 2.6 2 1 0 2 2 2 0 Histidine biosynthesis protein TetR_C_27 PF17935.1 KFM27996.1 - 0.02 15.0 0.0 0.043 13.9 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain NMO PF03060.15 KFM27996.1 - 0.37 10.1 7.1 0.69 9.2 0.3 2.3 2 0 0 2 2 2 0 Nitronate monooxygenase CBS PF00571.28 KFM27997.1 - 1.2e-14 54.5 1.6 0.00098 19.5 0.0 4.4 4 0 0 4 4 4 4 CBS domain TMP-TENI PF02581.17 KFM27997.1 - 0.03 13.6 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Thiamine monophosphate synthase rRNA_processing PF08524.11 KFM27998.1 - 3e-14 53.3 4.8 3e-14 53.3 4.8 1.9 2 0 0 2 2 2 1 rRNA processing SelB-wing_1 PF09105.10 KFM27998.1 - 0.38 10.8 4.5 4.4 7.4 1.4 2.4 2 0 0 2 2 2 0 Elongation factor SelB, winged helix Ldh_1_C PF02866.18 KFM28000.1 - 3.8e-34 118.0 0.0 5.4e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KFM28000.1 - 3e-27 95.4 0.0 4.4e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain OB_NTP_bind PF07717.16 KFM28002.1 - 5.7e-22 77.9 0.2 1.5e-21 76.5 0.1 1.8 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KFM28002.1 - 4.1e-19 68.8 0.0 7.2e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KFM28002.1 - 7.1e-13 48.9 0.0 1.4e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KFM28002.1 - 1.2e-07 32.1 0.1 6.1e-07 29.8 0.1 2.1 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 KFM28002.1 - 5.6e-07 29.5 0.3 1.4e-06 28.2 0.3 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 KFM28002.1 - 7.7e-05 23.1 0.2 0.00015 22.1 0.2 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KFM28002.1 - 0.00031 20.8 0.1 1 9.3 0.0 2.3 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 KFM28002.1 - 0.00085 19.1 1.3 0.17 11.6 0.1 2.2 1 1 1 2 2 2 2 IstB-like ATP binding protein AAA_30 PF13604.6 KFM28002.1 - 0.0022 17.7 0.2 0.0037 17.0 0.2 1.3 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 KFM28002.1 - 0.0044 17.0 0.1 0.0084 16.1 0.1 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain SRP54 PF00448.22 KFM28002.1 - 0.0045 16.6 0.9 0.013 15.1 0.9 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain DUF2075 PF09848.9 KFM28002.1 - 0.011 15.0 0.0 0.015 14.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 KFM28002.1 - 0.025 14.5 0.1 0.37 10.7 0.0 2.3 2 0 0 2 2 2 0 NACHT domain T2SSE PF00437.20 KFM28002.1 - 0.027 13.5 0.0 0.062 12.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.29 KFM28002.1 - 0.032 14.7 0.3 0.28 11.6 0.3 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KFM28002.1 - 0.063 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 KFM28002.1 - 0.084 12.9 0.1 0.22 11.5 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 KFM28002.1 - 0.086 13.4 0.7 0.43 11.1 0.1 2.1 2 0 0 2 2 2 0 ABC transporter cobW PF02492.19 KFM28002.1 - 0.1 12.2 0.4 1.4 8.5 0.2 2.5 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.18 KFM28002.1 - 0.12 11.7 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.6 KFM28002.1 - 0.15 12.4 0.1 0.38 11.1 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 KFM28002.1 - 0.16 12.0 0.1 1.6 8.8 0.1 2.3 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 KFM28002.1 - 0.17 11.3 0.1 0.72 9.3 0.1 2.0 2 0 0 2 2 2 0 PhoH-like protein TrwB_AAD_bind PF10412.9 KFM28002.1 - 0.22 10.4 0.3 0.4 9.5 0.3 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ETF PF01012.21 KFM28003.1 - 1.3e-42 145.8 4.1 1.6e-42 145.5 4.1 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain RraA-like PF03737.15 KFM28004.1 - 3.5e-42 144.1 1.5 4e-42 143.9 1.5 1.0 1 0 0 1 1 1 1 Aldolase/RraA Mito_carr PF00153.27 KFM28005.1 - 3e-51 171.3 1.4 7.1e-16 57.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KFM28005.1 - 0.0016 17.7 0.1 0.13 11.3 0.0 2.3 1 1 1 2 2 2 2 Gammaproteobacterial serine protease Aminotran_5 PF00266.19 KFM28006.1 - 7.3e-42 143.6 0.0 8.6e-42 143.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V FA_hydroxylase PF04116.13 KFM28009.1 - 3e-16 60.0 8.9 3e-16 60.0 8.9 2.3 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Es2 PF09751.9 KFM28010.1 - 8e-52 177.4 0.0 2.5e-51 175.8 0.0 1.7 1 1 0 1 1 1 1 Nuclear protein Es2 DUF1318 PF07027.12 KFM28010.1 - 0.13 12.7 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1318) p450 PF00067.22 KFM28011.1 - 7e-40 137.1 0.0 1.6e-39 136.0 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 SelB-wing_2 PF09106.11 KFM28011.1 - 0.077 13.2 0.1 2.2 8.6 0.0 2.9 2 0 0 2 2 2 0 Elongation factor SelB, winged helix Glyco_hydro_9 PF00759.19 KFM28012.1 - 7e-65 220.1 20.0 8.3e-65 219.8 20.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 CytB6-F_Fe-S PF08802.10 KFM28012.1 - 0.63 10.1 4.1 0.64 10.1 0.0 2.7 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit Glu_cyclase_2 PF05096.12 KFM28013.1 - 1.9e-73 247.0 0.0 2.5e-73 246.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine cyclotransferase SdiA-regulated PF06977.11 KFM28013.1 - 0.0063 15.8 0.0 0.1 11.8 0.0 2.2 2 0 0 2 2 2 1 SdiA-regulated Spc7 PF08317.11 KFM28015.1 - 0.0055 15.6 23.2 0.012 14.6 5.0 2.9 1 1 2 3 3 3 2 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 KFM28015.1 - 0.0071 16.4 9.1 0.0071 16.4 9.1 4.6 1 1 3 5 5 5 1 TPR/MLP1/MLP2-like protein DUF4763 PF15960.5 KFM28015.1 - 0.026 13.8 11.4 0.059 12.7 1.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4763) Fez1 PF06818.15 KFM28015.1 - 0.033 14.6 19.0 0.028 14.9 2.7 2.4 2 0 0 2 2 2 0 Fez1 Sec34 PF04136.15 KFM28015.1 - 0.045 13.6 0.9 0.13 12.1 0.5 1.9 1 1 0 1 1 1 0 Sec34-like family GIT_CC PF16559.5 KFM28015.1 - 0.057 13.3 0.6 7.1 6.6 0.2 3.2 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor GAS PF13851.6 KFM28015.1 - 0.064 12.6 24.7 0.14 11.5 0.1 3.2 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 KFM28015.1 - 0.092 12.8 4.0 1.5 8.9 1.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 KFM28015.1 - 0.15 12.1 4.8 4.9 7.2 2.1 2.7 2 0 0 2 2 2 0 Laminin Domain II DUF4407 PF14362.6 KFM28015.1 - 0.27 10.5 33.5 2.2 7.6 13.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) YabA PF06156.13 KFM28015.1 - 1 10.0 10.4 2.6 8.8 0.9 3.5 1 1 3 4 4 4 0 Initiation control protein YabA Spc24 PF08286.11 KFM28015.1 - 1.9 8.8 9.7 2.1 8.6 0.3 3.4 2 2 1 3 3 3 0 Spc24 subunit of Ndc80 DUF4201 PF13870.6 KFM28015.1 - 4 7.2 16.8 0.19 11.4 4.2 2.8 2 1 0 3 3 3 0 Domain of unknown function (DUF4201) APG6_N PF17675.1 KFM28015.1 - 4.9 7.7 39.9 0.68 10.5 6.4 3.6 1 1 2 3 3 3 0 Apg6 coiled-coil region GldM_N PF12081.8 KFM28015.1 - 5.2 7.1 8.7 7.9 6.5 1.5 2.8 2 2 0 2 2 2 0 GldM N-terminal domain Rootletin PF15035.6 KFM28015.1 - 5.7 6.9 24.8 0.015 15.4 9.9 2.5 1 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion FapA PF03961.13 KFM28015.1 - 6.1 5.3 9.4 4.5 5.8 2.9 2.3 1 1 0 2 2 2 0 Flagellar Assembly Protein A TarH PF02203.15 KFM28015.1 - 6.1 6.7 18.3 0.52 10.2 1.2 3.3 1 1 0 3 3 3 0 Tar ligand binding domain homologue Snapin_Pallidin PF14712.6 KFM28015.1 - 7.3 7.1 10.3 11 6.5 0.5 3.5 2 1 1 4 4 3 0 Snapin/Pallidin AATF-Che1 PF13339.6 KFM28015.1 - 9.4 6.9 13.5 2.2 8.9 1.4 2.9 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor Cellulase PF00150.18 KFM28016.1 - 2.4e-15 56.7 6.4 4e-15 56.0 6.4 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) AP_endonuc_2 PF01261.24 KFM28016.1 - 0.01 15.3 0.0 0.37 10.2 0.0 2.2 2 0 0 2 2 2 2 Xylose isomerase-like TIM barrel MFS_1 PF07690.16 KFM28017.1 - 1.6e-36 126.0 29.4 1.6e-36 126.0 29.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1690 PF07956.11 KFM28019.1 - 0.18 12.2 12.9 1.7 9.1 0.2 3.1 2 1 0 3 3 3 0 Protein of Unknown function (DUF1690) Motile_Sperm PF00635.26 KFM28021.1 - 7.2e-27 93.4 0.5 1.1e-26 92.8 0.5 1.3 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Dynamitin PF04912.14 KFM28021.1 - 0.064 12.6 0.1 0.074 12.4 0.1 1.1 1 0 0 1 1 1 0 Dynamitin NAD_binding_1 PF00175.21 KFM28023.1 - 2e-24 86.3 0.0 3.4e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KFM28023.1 - 2.9e-17 62.8 0.0 5.4e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KFM28023.1 - 0.0014 18.8 0.0 0.12 12.5 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Amino_oxidase PF01593.24 KFM28024.1 - 1.1e-73 249.1 0.0 1.3e-73 248.9 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFM28024.1 - 6.4e-11 42.3 0.0 1.8e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KFM28024.1 - 5.9e-05 22.4 0.1 0.00011 21.5 0.1 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KFM28024.1 - 6.3e-05 22.7 1.1 0.0003 20.5 0.8 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFM28024.1 - 0.0084 15.4 0.1 0.014 14.6 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFM28024.1 - 0.015 14.4 0.1 0.21 10.6 1.4 2.0 1 1 1 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 KFM28024.1 - 0.021 14.8 0.2 0.055 13.5 0.1 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KFM28024.1 - 0.035 13.3 0.0 0.051 12.8 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 KFM28024.1 - 0.054 12.8 0.1 0.17 11.2 0.4 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KFM28024.1 - 0.066 12.1 0.0 0.091 11.6 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 KFM28024.1 - 0.15 11.3 0.2 0.28 10.4 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.21 KFM28025.1 - 8.1e-62 208.8 0.1 1.1e-61 208.3 0.1 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 KFM28025.1 - 9e-13 48.7 0.0 2.3e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Sacchrp_dh_NADP PF03435.18 KFM28025.1 - 0.016 15.5 1.2 0.079 13.2 0.9 2.3 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain FAD_binding_3 PF01494.19 KFM28025.1 - 0.016 14.4 1.5 0.025 13.8 1.5 1.2 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 KFM28025.1 - 0.022 14.3 0.9 0.038 13.6 0.9 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.16 KFM28025.1 - 0.059 13.0 0.4 0.099 12.3 0.4 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HALZ PF02183.18 KFM28025.1 - 0.13 12.5 2.0 0.29 11.4 2.0 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper DivIC PF04977.15 KFM28025.1 - 0.18 11.6 0.9 0.37 10.6 0.9 1.5 1 0 0 1 1 1 0 Septum formation initiator NUDE_C PF04880.13 KFM28025.1 - 0.2 12.1 1.5 0.66 10.4 0.3 2.0 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region Mto2_bdg PF12808.7 KFM28025.1 - 0.41 11.0 2.7 0.46 10.8 1.2 1.9 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Mitoc_mL59 PF18126.1 KFM28026.1 - 2.4e-08 34.4 6.9 6.5e-07 29.7 6.9 2.2 1 1 0 1 1 1 1 Mitochondrial ribosomal protein mL59 HD_assoc PF13286.6 KFM28026.1 - 0.078 13.5 0.3 0.54 10.8 0.1 2.1 1 1 1 2 2 2 0 Phosphohydrolase-associated domain adh_short PF00106.25 KFM28028.1 - 2e-35 122.0 0.1 5.3e-23 81.5 0.1 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFM28028.1 - 1.1e-25 90.6 0.0 1.7e-16 60.5 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM28028.1 - 4.9e-12 46.1 0.1 8.2e-12 45.4 0.1 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KFM28028.1 - 1.8e-10 41.0 0.0 9.4e-10 38.7 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KFM28028.1 - 0.00093 18.7 0.0 0.0015 18.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KFM28028.1 - 0.036 13.2 0.1 1.1 8.3 0.0 2.5 1 1 1 2 2 2 0 Male sterility protein ADH_zinc_N PF00107.26 KFM28028.1 - 0.052 13.5 0.0 0.21 11.6 0.0 1.9 2 0 0 2 2 2 0 Zinc-binding dehydrogenase TrkA_N PF02254.18 KFM28028.1 - 0.082 13.2 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain 3Beta_HSD PF01073.19 KFM28028.1 - 0.098 11.6 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KFM28028.1 - 0.098 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain DapB_N PF01113.20 KFM28028.1 - 0.12 12.5 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 KFM28029.1 - 3.1e-33 114.9 0.1 4.4e-33 114.4 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM28029.1 - 4.6e-27 95.1 0.1 5.8e-27 94.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM28029.1 - 1.6e-10 41.2 0.1 2.1e-10 40.8 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KFM28029.1 - 4.4e-09 36.5 0.1 8.4e-09 35.6 0.1 1.5 1 1 0 1 1 1 1 NAD(P)H-binding ADH_zinc_N PF00107.26 KFM28029.1 - 0.019 14.9 0.0 0.048 13.6 0.0 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 KFM28031.1 - 4.1e-05 24.2 0.0 7.8e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFM28031.1 - 0.00043 20.9 0.0 0.0013 19.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_24 PF13578.6 KFM28031.1 - 0.0074 17.3 0.0 0.04 14.9 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Ank_2 PF12796.7 KFM28031.1 - 0.014 16.0 0.0 0.024 15.2 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Pcc1 PF09341.10 KFM28032.1 - 1.4e-08 34.8 0.1 1.4e-08 34.7 0.1 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 Bestrophin PF01062.21 KFM28033.1 - 5.2e-50 170.5 1.2 6.5e-50 170.2 1.2 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel TPR_2 PF07719.17 KFM28034.1 - 3.4e-05 23.6 7.6 0.044 13.9 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFM28034.1 - 0.0012 19.5 16.1 0.0012 19.5 16.1 2.7 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFM28034.1 - 0.0026 18.4 26.0 0.0032 18.2 1.3 3.9 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFM28034.1 - 0.026 15.0 13.5 1.4 9.4 7.2 3.0 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_5 PF12688.7 KFM28034.1 - 0.091 13.0 11.0 1.6 9.0 5.8 3.0 1 1 1 2 2 2 0 Tetratrico peptide repeat TPR_12 PF13424.6 KFM28034.1 - 0.48 10.8 8.7 11 6.4 0.1 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFM28034.1 - 0.89 9.5 3.0 3.2 7.7 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Got1 PF04178.12 KFM28035.1 - 4.9e-34 117.1 13.1 6.2e-34 116.8 13.1 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family Abhydrolase_6 PF12697.7 KFM28036.1 - 9.8e-26 91.7 5.9 1.4e-25 91.2 5.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFM28036.1 - 5.1e-25 88.6 0.1 7.3e-25 88.1 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFM28036.1 - 6.8e-17 61.5 0.1 3.5e-16 59.2 0.1 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 KFM28036.1 - 0.00014 21.6 0.4 0.00043 20.0 0.1 1.9 2 0 0 2 2 2 1 Putative esterase Thioesterase PF00975.20 KFM28036.1 - 0.0013 19.0 0.1 0.0018 18.4 0.1 1.2 1 0 0 1 1 1 1 Thioesterase domain LIDHydrolase PF10230.9 KFM28036.1 - 0.0071 15.9 0.0 0.018 14.6 0.0 1.6 1 1 0 1 1 1 1 Lipid-droplet associated hydrolase Ser_hydrolase PF06821.13 KFM28036.1 - 0.014 15.3 0.1 0.19 11.6 0.0 2.6 2 1 1 3 3 3 0 Serine hydrolase DUF3141 PF11339.8 KFM28036.1 - 0.25 9.7 0.3 0.39 9.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) LRR_6 PF13516.6 KFM28037.1 - 4.3e-13 48.2 4.2 0.064 13.3 0.1 7.9 8 0 0 8 8 8 3 Leucine Rich repeat LRR_1 PF00560.33 KFM28037.1 - 1.1e-05 25.3 0.6 61 4.8 0.0 6.6 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_4 PF12799.7 KFM28037.1 - 9.1e-05 22.8 9.7 0.11 12.9 0.1 5.5 3 1 4 7 7 7 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFM28037.1 - 0.0096 15.7 14.3 0.22 11.3 2.3 5.6 2 1 3 5 5 5 3 Leucine rich repeat EamA PF00892.20 KFM28038.1 - 2.7e-21 76.2 11.7 9.2e-12 45.3 2.8 2.5 2 0 0 2 2 2 2 EamA-like transporter family OrfB_Zn_ribbon PF07282.11 KFM28038.1 - 0.0085 16.0 5.9 0.028 14.3 5.9 1.8 1 1 0 1 1 1 1 Putative transposase DNA-binding domain TMEM234 PF10639.9 KFM28038.1 - 0.011 15.7 3.3 1.9 8.5 0.3 2.4 2 0 0 2 2 2 0 Putative transmembrane family 234 PUNUT PF16913.5 KFM28038.1 - 0.11 11.6 4.1 2.8 7.1 0.3 2.1 1 1 1 2 2 2 0 Purine nucleobase transmembrane transport TPT PF03151.16 KFM28038.1 - 0.2 10.9 1.9 10 5.4 0.3 2.1 1 1 1 2 2 2 0 Triose-phosphate Transporter family CbtB PF09489.10 KFM28038.1 - 0.31 11.2 3.7 19 5.5 0.1 3.1 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) DUF3488 PF11992.8 KFM28038.1 - 0.36 9.7 8.2 1.6 7.6 1.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3488) OTT_1508_deam PF14441.6 KFM28038.1 - 0.87 9.6 4.8 0.27 11.3 0.9 2.0 2 0 0 2 2 2 0 OTT_1508-like deaminase Phageshock_PspG PF09583.10 KFM28038.1 - 1.5 9.1 13.1 7.5 6.9 2.5 2.9 2 0 0 2 2 2 0 Phage shock protein G (Phageshock_PspG) Syja_N PF02383.18 KFM28041.1 - 2.4e-33 115.8 0.0 3e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain WW PF00397.26 KFM28041.1 - 0.0064 16.5 0.3 0.0064 16.5 0.3 1.9 2 0 0 2 2 2 1 WW domain Abhydrolase_2 PF02230.16 KFM28042.1 - 8.7e-37 127.0 0.0 1.2e-36 126.6 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KFM28042.1 - 2.7e-09 36.6 0.1 1.8e-06 27.4 0.0 2.9 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFM28042.1 - 7e-07 30.1 1.3 8.8e-07 29.8 1.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KFM28042.1 - 1.8e-05 24.4 0.0 2.5e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 KFM28042.1 - 0.00013 21.6 0.0 0.00026 20.6 0.0 1.4 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KFM28042.1 - 0.00038 20.2 0.1 0.71 9.5 0.0 2.8 2 1 1 3 3 3 2 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 KFM28042.1 - 0.003 17.1 0.0 0.009 15.6 0.0 1.7 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region LIP PF03583.14 KFM28042.1 - 0.2 10.9 0.0 0.63 9.3 0.0 1.6 1 1 1 2 2 2 0 Secretory lipase ANAPC4_WD40 PF12894.7 KFM28043.1 - 0.088 13.1 0.0 1.2 9.5 0.0 2.6 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain CMS1 PF14617.6 KFM28044.1 - 1.2e-26 93.6 0.0 1.8e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 KFM28044.1 - 3e-05 23.9 0.0 3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Acetyltransf_6 PF13480.7 KFM28044.1 - 0.09 12.9 0.8 0.19 11.9 0.8 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PPR_2 PF13041.6 KFM28045.1 - 2.4e-39 133.3 0.1 3.1e-10 40.1 0.0 6.2 2 1 3 6 6 6 5 PPR repeat family PPR_3 PF13812.6 KFM28045.1 - 5.1e-30 103.4 0.0 5.2e-14 52.1 0.0 5.5 2 1 3 6 6 6 5 Pentatricopeptide repeat domain PPR PF01535.20 KFM28045.1 - 5.2e-25 85.9 4.7 7.5e-07 29.0 0.0 6.6 7 0 0 7 7 7 5 PPR repeat PPR_1 PF12854.7 KFM28045.1 - 8.1e-25 86.2 0.6 4.2e-08 32.8 0.0 6.9 7 0 0 7 7 7 4 PPR repeat PPR_long PF17177.4 KFM28045.1 - 9.6e-16 57.8 5.1 1e-11 44.7 0.3 3.1 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP Cyclin_C PF02984.19 KFM28045.1 - 3.5e-05 23.9 0.7 8.9e-05 22.6 0.7 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Glyco_trans_4_3 PF12000.8 KFM28045.1 - 0.017 14.8 0.1 3 7.5 0.0 3.4 2 1 2 4 4 4 0 Glycosyl transferase family 4 group TPR_7 PF13176.6 KFM28045.1 - 0.026 14.6 0.3 4 7.7 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat PIG-X PF08320.12 KFM28046.1 - 5.9e-13 49.2 1.6 1.8e-06 28.0 0.0 3.0 2 1 0 2 2 2 2 PIG-X / PBN1 Glucosamine_iso PF01182.20 KFM28048.1 - 3.2e-61 207.1 0.0 4.3e-61 206.6 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Clat_adaptor_s PF01217.20 KFM28048.1 - 0.0019 18.2 0.0 0.0029 17.6 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Mito_carr PF00153.27 KFM28049.1 - 6e-19 67.8 7.6 2e-10 40.4 0.4 3.7 3 0 0 3 3 3 3 Mitochondrial carrier protein tRNA-synt_1e PF01406.19 KFM28050.1 - 4.1e-122 407.3 0.0 1.6e-121 405.3 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KFM28050.1 - 5.8e-10 38.5 0.0 0.00034 19.5 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.11 KFM28050.1 - 2.5e-05 24.6 0.0 4.8e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 DALR domain tRNA-synt_1f PF01921.18 KFM28050.1 - 8.5e-05 21.6 0.0 0.00062 18.8 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (K) tRNA-synt_1 PF00133.22 KFM28050.1 - 0.00032 19.1 0.0 0.00084 17.7 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Aminotran_3 PF00202.21 KFM28051.1 - 2.6e-109 365.6 0.0 3.1e-109 365.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Pro_isomerase PF00160.21 KFM28052.1 - 3.5e-48 163.9 0.0 5.1e-48 163.3 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TRIC PF05197.13 KFM28052.1 - 5.5e-09 35.9 0.1 8e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 TRIC channel CLN3 PF02487.17 KFM28054.1 - 1.2e-74 251.8 8.7 1.2e-39 136.5 2.2 2.0 2 0 0 2 2 2 2 CLN3 protein MFS_1 PF07690.16 KFM28054.1 - 0.0025 16.8 40.1 0.0071 15.3 40.1 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Methyltransf_5 PF01795.19 KFM28055.1 - 3.2e-71 240.4 0.0 3.9e-71 240.1 0.0 1.0 1 0 0 1 1 1 1 MraW methylase family DUF1556 PF07590.11 KFM28055.1 - 0.0018 18.5 1.2 0.0079 16.5 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1556) Ribonuc_L-PSP PF01042.21 KFM28056.1 - 2.4e-20 72.8 0.0 2.4e-20 72.8 0.0 3.4 3 1 0 3 3 3 1 Endoribonuclease L-PSP Cas1_AcylT PF07779.12 KFM28058.1 - 2.9e-85 287.0 5.0 3.5e-84 283.4 5.0 1.9 1 1 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p SNARE_assoc PF09335.11 KFM28059.1 - 1e-20 74.4 10.1 1e-20 74.4 10.1 1.8 2 0 0 2 2 2 1 SNARE associated Golgi protein Patatin PF01734.22 KFM28060.1 - 1.3e-25 90.8 0.7 2.4e-25 89.9 0.3 1.7 2 0 0 2 2 2 1 Patatin-like phospholipase DUF3336 PF11815.8 KFM28060.1 - 7e-15 54.9 0.0 1.2e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Rieske PF00355.26 KFM28061.1 - 5.4e-11 42.3 0.2 7.4e-11 41.8 0.2 1.2 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain CytB6-F_Fe-S PF08802.10 KFM28061.1 - 4.6e-08 33.0 1.7 9.4e-08 32.0 1.7 1.5 1 0 0 1 1 1 1 Cytochrome B6-F complex Fe-S subunit WHAMM-JMY_N PF15920.5 KFM28061.1 - 0.026 14.4 0.6 0.047 13.5 0.6 1.4 1 0 0 1 1 1 0 N-terminal of Junction-mediating and WASP homolog-associated SKA2 PF16740.5 KFM28062.1 - 9.2e-18 64.0 0.1 1.1e-17 63.8 0.1 1.0 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 Scaffolding_pro PF11418.8 KFM28062.1 - 0.034 14.7 0.0 0.047 14.3 0.0 1.3 1 0 0 1 1 1 0 Phi29 scaffolding protein TMF_TATA_bd PF12325.8 KFM28062.1 - 0.085 13.1 0.4 0.76 10.0 0.0 2.0 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding TPR_MLP1_2 PF07926.12 KFM28062.1 - 0.16 12.0 1.7 4 7.5 1.8 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF2201 PF09967.9 KFM28062.1 - 0.17 12.0 0.0 0.3 11.3 0.0 1.4 1 1 1 2 2 2 0 VWA-like domain (DUF2201) GCP_N_terminal PF17681.1 KFM28063.1 - 7.5e-05 22.5 0.0 0.00012 21.8 0.0 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KFM28063.1 - 0.053 13.0 0.0 0.087 12.3 0.0 1.4 1 0 0 1 1 1 0 Gamma tubulin complex component C-terminal FA_desaturase_2 PF03405.14 KFM28064.1 - 1.4e-137 457.9 0.0 1.7e-137 457.7 0.0 1.0 1 0 0 1 1 1 1 Fatty acid desaturase Pyridoxal_deC PF00282.19 KFM28065.1 - 6.2e-107 357.6 0.0 7.4e-107 357.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 KFM28065.1 - 0.00016 21.1 0.0 0.00024 20.5 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KFM28065.1 - 0.0099 15.1 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KFM28065.1 - 0.015 14.2 0.0 0.023 13.7 0.0 1.5 1 1 0 1 1 1 0 Aminotransferase class-V Glyco_transf_21 PF13506.6 KFM28065.1 - 0.072 12.6 0.1 2.4 7.6 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 21 Replicase PF03090.17 KFM28065.1 - 0.089 12.6 0.0 0.44 10.4 0.0 2.0 2 0 0 2 2 2 0 Replicase family LYTB PF02401.18 KFM28066.1 - 9.2e-74 248.0 0.0 1.2e-73 247.6 0.0 1.1 1 0 0 1 1 1 1 LytB protein Cpn60_TCP1 PF00118.24 KFM28067.1 - 7.5e-89 298.6 13.5 1.3e-88 297.8 13.5 1.3 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family TRAPP PF04051.16 KFM28069.1 - 4.2e-28 97.9 0.0 8.2e-28 97.0 0.0 1.4 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component OTCace_N PF02729.21 KFM28070.1 - 5.1e-44 149.9 0.0 8.7e-44 149.1 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 KFM28070.1 - 3.2e-26 92.3 0.0 6.8e-26 91.2 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain DPBB_1 PF03330.18 KFM28071.1 - 2.5e-05 24.5 0.2 5.1e-05 23.5 0.2 1.5 1 0 0 1 1 1 1 Lytic transglycolase SufE PF02657.15 KFM28072.1 - 3.5e-35 120.5 0.0 5.5e-35 119.9 0.0 1.2 1 0 0 1 1 1 1 Fe-S metabolism associated domain BolA PF01722.18 KFM28072.1 - 4.8e-29 100.5 0.2 7.3e-29 99.9 0.2 1.3 1 0 0 1 1 1 1 BolA-like protein Pantoate_transf PF02548.15 KFM28073.1 - 1.9e-101 338.9 2.8 2.3e-101 338.6 2.8 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 KFM28073.1 - 6.4e-09 35.6 1.3 4.7e-08 32.8 1.2 2.0 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Asp_Glu_race PF01177.22 KFM28073.1 - 0.027 14.3 0.0 0.12 12.2 0.1 1.9 2 0 0 2 2 2 0 Asp/Glu/Hydantoin racemase FA_desaturase PF00487.24 KFM28074.1 - 2.2e-21 76.8 15.3 2.2e-21 76.8 15.3 1.9 1 1 1 2 2 2 2 Fatty acid desaturase Lipid_DES PF08557.10 KFM28074.1 - 5.7e-13 48.1 0.6 1.1e-12 47.2 0.0 1.8 2 0 0 2 2 2 1 Sphingolipid Delta4-desaturase (DES) DUF716 PF04819.12 KFM28075.1 - 4.2e-10 39.4 0.5 7.6e-10 38.6 0.5 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF716) GHMP_kinases_N PF00288.26 KFM28076.1 - 8.2e-11 42.0 5.2 8.2e-11 42.0 5.2 2.3 3 0 0 3 3 3 1 GHMP kinases N terminal domain Radical_SAM PF04055.21 KFM28077.1 - 8.7e-17 62.0 0.0 1.5e-16 61.2 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily LIAS_N PF16881.5 KFM28077.1 - 8.3e-07 29.4 0.0 1.2e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family PALP PF00291.25 KFM28078.1 - 6.7e-52 176.7 0.1 8.6e-52 176.4 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CD36 PF01130.21 KFM28079.1 - 2.9e-44 151.4 0.0 1.1e-21 77.0 0.0 2.1 2 0 0 2 2 2 2 CD36 family GTP_EFTU_D3 PF03143.17 KFM28080.1 - 2.5e-17 63.2 0.0 3.8e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU PF00009.27 KFM28080.1 - 8.8e-09 35.2 0.0 0.0028 17.2 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain WD40 PF00400.32 KFM28081.1 - 2.7e-26 91.3 1.1 0.00012 22.8 0.0 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM28081.1 - 5.6e-11 42.6 0.1 0.02 15.2 0.0 4.8 3 2 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFM28081.1 - 0.00069 18.7 0.3 0.7 8.8 0.0 3.6 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KFM28081.1 - 0.047 12.4 0.0 0.062 12.0 0.0 1.3 1 0 0 1 1 1 0 Nup133 N terminal like Nup160 PF11715.8 KFM28081.1 - 0.071 11.7 0.1 0.13 10.9 0.1 1.4 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Xpo1 PF08389.12 KFM28082.1 - 0.00022 21.3 0.1 0.00038 20.5 0.1 1.4 1 0 0 1 1 1 1 Exportin 1-like protein Acyl_transf_1 PF00698.21 KFM28083.1 - 1.5e-26 93.7 0.3 2.5e-26 92.9 0.3 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ank_5 PF13857.6 KFM28083.1 - 2.2e-09 37.4 0.1 0.00013 22.2 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KFM28083.1 - 1.1e-08 35.1 0.1 0.00011 22.5 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KFM28083.1 - 8.3e-08 32.6 0.0 1.3e-05 25.6 0.0 2.9 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM28083.1 - 1.5e-07 31.9 0.0 4.2e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFM28083.1 - 0.00083 19.6 0.1 0.13 12.9 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat SAT PF16073.5 KFM28083.1 - 0.0072 16.1 0.1 0.017 14.9 0.1 1.7 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Rubrerythrin PF02915.17 KFM28084.1 - 3.2e-37 128.0 0.0 3.2e-37 128.0 0.0 2.3 3 0 0 3 3 3 1 Rubrerythrin DUF1682 PF07946.14 KFM28084.1 - 3.1e-30 105.5 12.4 5e-29 101.5 0.0 2.5 2 1 1 3 3 3 1 Protein of unknown function (DUF1682) DUF4812 PF16071.5 KFM28084.1 - 0.1 12.4 0.5 0.34 10.8 0.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4812) FA_desaturase_2 PF03405.14 KFM28084.1 - 2.8 6.7 5.6 12 4.6 0.0 2.7 3 0 0 3 3 3 0 Fatty acid desaturase zf-4CXXC_R1 PF10497.9 KFM28085.1 - 1.5e-26 92.5 10.2 4e-26 91.1 10.2 1.7 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 WHIM1 PF15612.6 KFM28085.1 - 0.0013 18.3 0.0 0.0029 17.1 0.0 1.5 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 PHD_4 PF16866.5 KFM28085.1 - 0.016 15.2 4.2 0.016 15.2 4.2 1.8 2 0 0 2 2 2 0 PHD-finger Tankyrase_bdg_C PF15327.6 KFM28085.1 - 0.44 11.0 2.5 2.2 8.7 2.5 2.0 1 1 0 1 1 1 0 Tankyrase binding protein C terminal domain EF-hand_6 PF13405.6 KFM28086.1 - 1.4e-22 77.7 0.7 4.9e-05 22.9 0.0 5.2 5 0 0 5 5 5 5 EF-hand domain EF-hand_1 PF00036.32 KFM28086.1 - 5e-22 75.8 0.0 0.00077 18.8 0.0 5.3 6 0 0 6 6 6 5 EF hand EF-hand_7 PF13499.6 KFM28086.1 - 1.3e-20 73.6 0.1 7.2e-10 39.2 0.1 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 KFM28086.1 - 8.1e-14 51.2 0.1 0.00014 21.6 0.0 4.7 3 2 2 5 5 5 3 EF-hand domain pair EF-hand_5 PF13202.6 KFM28086.1 - 7.2e-13 47.4 0.2 0.00018 20.8 0.1 4.6 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KFM28086.1 - 0.00012 22.3 0.0 8.4 6.8 0.0 3.4 3 1 0 3 3 3 3 EF-hand domain EF-hand_10 PF14788.6 KFM28086.1 - 0.0035 17.2 0.3 7.5 6.5 0.0 3.2 2 1 1 3 3 3 3 EF hand SPARC_Ca_bdg PF10591.9 KFM28086.1 - 0.11 12.9 0.0 1.1 9.6 0.0 2.0 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region NOT2_3_5 PF04153.18 KFM28087.1 - 1.8e-29 102.4 0.3 2.6e-29 101.9 0.3 1.2 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family eIF3_subunit PF08597.10 KFM28088.1 - 1.4e-34 120.1 11.7 1e-33 117.2 11.7 1.9 1 1 0 1 1 1 1 Translation initiation factor eIF3 subunit ERCC4 PF02732.15 KFM28089.1 - 2.6e-16 60.2 0.0 4e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 ERCC4 domain SMC_N PF02463.19 KFM28090.1 - 1.1e-11 44.6 0.0 7.6e-11 41.9 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 KFM28090.1 - 7.4e-07 29.3 0.0 1.8e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 KFM28090.1 - 1.5e-05 25.6 0.0 2.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KFM28090.1 - 0.024 15.1 0.1 0.83 10.2 0.0 2.8 2 0 0 2 2 2 0 ABC transporter Metallophos PF00149.28 KFM28091.1 - 0.0097 16.4 0.0 0.01 16.4 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Sec1 PF00995.23 KFM28093.1 - 1.3e-56 193.1 0.0 8.1e-56 190.4 0.0 1.7 1 1 1 2 2 2 1 Sec1 family CRCB PF02537.15 KFM28094.1 - 7e-28 96.8 19.6 2.3e-14 53.4 6.4 2.3 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) CPP1-like PF11833.8 KFM28094.1 - 0.77 9.4 7.6 1.7 8.3 0.2 3.3 3 0 0 3 3 3 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Tmemb_14 PF03647.13 KFM28095.1 - 1.3e-11 45.0 5.6 1.8e-11 44.6 5.6 1.2 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF4131 PF13567.6 KFM28095.1 - 0.061 13.0 0.0 0.061 13.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) ThiF PF00899.21 KFM28097.1 - 6.5e-63 212.3 0.0 8.9e-63 211.9 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 KFM28097.1 - 1.7e-12 47.3 0.0 3e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 E2 binding domain Ecm33 PF12454.8 KFM28097.1 - 0.17 12.1 0.5 0.32 11.2 0.5 1.4 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein GATase PF00117.28 KFM28098.1 - 6.9e-45 153.2 0.0 8.4e-45 152.9 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KFM28098.1 - 5.5e-12 45.9 0.2 1e-11 45.0 0.2 1.4 1 1 0 1 1 1 1 Peptidase C26 BRE1 PF08647.11 KFM28099.1 - 0.6 10.2 8.1 1.6 8.8 1.9 3.2 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase FlxA PF14282.6 KFM28099.1 - 1.5 8.9 9.1 5.1 7.1 9.1 1.9 1 0 0 1 1 1 0 FlxA-like protein CEP63 PF17045.5 KFM28099.1 - 3.7 7.4 15.7 1.5 8.7 1.4 2.7 2 1 0 2 2 2 0 Centrosomal protein of 63 kDa TFIIA PF03153.13 KFM28099.1 - 5.3 6.9 6.8 6.6 6.6 6.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Elf1 PF05129.13 KFM28100.1 - 2.2e-29 101.3 1.8 2.5e-29 101.1 1.8 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Lar_restr_allev PF14354.6 KFM28100.1 - 0.014 15.8 2.4 0.019 15.4 2.4 1.3 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf-C2H2_4 PF13894.6 KFM28100.1 - 0.2 12.6 3.4 11 7.1 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger T4_baseplate PF12322.8 KFM28100.1 - 0.25 10.8 1.6 1.4 8.3 0.3 1.9 1 1 1 2 2 2 0 T4 bacteriophage base plate protein zinc_ribbon_4 PF13717.6 KFM28100.1 - 1.1 9.2 6.0 0.81 9.7 0.3 2.4 1 1 1 2 2 2 0 zinc-ribbon domain SH3_9 PF14604.6 KFM28101.1 - 2.7e-12 46.3 0.2 6.8e-08 32.2 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KFM28101.1 - 3.3e-12 45.8 0.0 5.8e-06 25.8 0.0 2.3 2 0 0 2 2 2 2 SH3 domain SH3_3 PF08239.11 KFM28101.1 - 0.00014 22.1 0.0 0.022 15.0 0.0 2.4 2 0 0 2 2 2 2 Bacterial SH3 domain SH3_16 PF18348.1 KFM28101.1 - 0.13 12.1 0.7 25 4.7 0.1 2.8 2 0 0 2 2 2 0 Bacterial dipeptidyl-peptidase Sh3 domain zf_CCCH_4 PF18345.1 KFM28103.1 - 9.8e-06 25.5 0.4 9.8e-06 25.5 0.4 4.2 5 0 0 5 5 5 1 Zinc finger domain zf-CCCH PF00642.24 KFM28103.1 - 3.8e-05 23.5 0.3 3.8e-05 23.5 0.3 3.7 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 KFM28103.1 - 0.001 19.4 20.0 0.0057 17.1 1.2 3.7 3 0 0 3 3 3 2 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 KFM28103.1 - 0.0064 16.3 1.2 0.0064 16.3 1.2 3.6 4 0 0 4 4 4 1 CCCH-type zinc finger Torus PF16131.5 KFM28103.1 - 0.3 11.8 2.7 0.69 10.6 1.7 2.1 2 0 0 2 2 2 0 Torus domain PP28 PF10252.9 KFM28104.1 - 0.0035 17.7 7.2 0.0085 16.5 7.2 1.7 1 1 0 1 1 1 1 Casein kinase substrate phosphoprotein PP28 OrfB_Zn_ribbon PF07282.11 KFM28104.1 - 0.0044 16.9 0.1 0.013 15.5 0.1 1.7 1 0 0 1 1 1 1 Putative transposase DNA-binding domain CDP-OH_P_transf PF01066.21 KFM28105.1 - 1.2e-15 58.0 0.5 1.2e-15 58.0 0.5 1.8 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF4231 PF14015.6 KFM28105.1 - 5.5 7.5 6.0 1.3 9.6 1.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) DUF3040 PF11239.8 KFM28106.1 - 0.03 14.6 0.1 0.03 14.6 0.1 3.3 4 1 0 4 4 4 0 Protein of unknown function (DUF3040) Sugar_tr PF00083.24 KFM28107.1 - 4.2e-81 273.1 16.3 1.1e-43 149.8 6.5 3.0 1 1 2 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.16 KFM28107.1 - 4.8e-20 71.8 39.4 7.8e-19 67.8 40.5 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KFM28107.1 - 0.00074 18.1 3.1 0.0011 17.5 3.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sde2_N_Ubi PF13019.6 KFM28108.1 - 1e-22 80.7 0.7 1.5e-22 80.1 0.7 1.3 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain Telomere_Sde2_2 PF13297.6 KFM28108.1 - 1.6e-22 78.9 2.5 1.6e-22 78.9 2.5 1.7 2 0 0 2 2 2 1 Telomere stability C-terminal DPCD PF14913.6 KFM28108.1 - 0.21 10.9 0.2 0.29 10.5 0.2 1.1 1 0 0 1 1 1 0 DPCD protein family RRM_1 PF00076.22 KFM28109.1 - 4.5e-17 61.6 0.0 7.5e-17 60.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFM28109.1 - 0.0047 16.5 0.0 0.0074 15.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 KFM28109.1 - 0.018 15.0 0.1 0.04 13.9 0.1 1.6 1 0 0 1 1 1 0 RL domain Nup35_RRM_2 PF14605.6 KFM28109.1 - 0.031 14.3 0.2 0.055 13.5 0.2 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KFM28109.1 - 0.034 14.3 0.1 0.075 13.2 0.1 1.6 1 1 0 1 1 1 0 RNA recognition motif RRM_1 PF00076.22 KFM28111.1 - 0.0064 16.3 0.0 1 9.2 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFM28111.1 - 0.071 13.2 0.0 1.3 9.2 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif RRM_9 PF18444.1 KFM28111.1 - 0.1 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif DUF98 PF01947.16 KFM28112.1 - 9.6e-48 161.9 0.0 7e-47 159.1 0.0 1.9 1 1 0 1 1 1 1 p-hydroxybenzoic acid synthase Bax1-I PF01027.20 KFM28113.1 - 7.6e-31 107.5 19.4 1e-30 107.1 19.4 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 RNase_PH PF01138.21 KFM28114.1 - 2.3e-23 83.2 0.0 6.4e-09 36.4 0.0 3.4 2 1 1 3 3 3 3 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KFM28114.1 - 1.1e-11 44.5 0.9 1.7e-11 44.0 0.1 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 PS_Dcarbxylase PF02666.15 KFM28115.1 - 6.7e-55 185.7 0.0 1e-54 185.2 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase EF-hand_1 PF00036.32 KFM28115.1 - 0.02 14.4 0.0 0.051 13.1 0.0 1.7 1 0 0 1 1 1 0 EF hand CCDC142 PF14923.6 KFM28116.1 - 0.023 13.5 0.1 0.032 13.0 0.1 1.1 1 0 0 1 1 1 0 Coiled-coil protein 142 TrbI_Ftype PF09677.10 KFM28116.1 - 0.1 12.9 3.0 2.7 8.4 0.7 2.3 1 1 1 2 2 2 0 Type-F conjugative transfer system protein (TrbI_Ftype) PIG-S PF10510.9 KFM28117.1 - 0.0031 16.4 0.5 0.0041 16.0 0.5 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Glyoxalase PF00903.25 KFM28118.1 - 2.4e-08 34.2 0.0 3.9e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KFM28118.1 - 0.0041 17.4 0.0 0.0062 16.8 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KFM28118.1 - 0.02 15.7 0.0 0.031 15.1 0.0 1.3 1 0 0 1 1 1 0 Glyoxalase-like domain RRM_1 PF00076.22 KFM28119.1 - 1.6e-09 37.4 0.0 9.3e-08 31.8 0.0 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PEMT PF04191.13 KFM28121.1 - 3.3e-12 46.7 1.3 3.3e-12 46.7 1.3 2.5 3 0 0 3 3 3 1 Phospholipid methyltransferase DUF1295 PF06966.12 KFM28121.1 - 1.7e-05 24.5 2.5 2.6e-05 23.8 2.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.17 KFM28121.1 - 4.4e-05 22.4 0.5 0.00016 20.6 0.0 1.9 2 0 0 2 2 2 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.14 KFM28121.1 - 0.0026 18.2 2.2 0.0028 18.1 0.1 2.2 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Polysacc_synt_C PF14667.6 KFM28121.1 - 5.2 7.1 13.9 6.2 6.9 9.9 2.6 1 1 1 2 2 2 0 Polysaccharide biosynthesis C-terminal domain MCD PF05292.11 KFM28122.1 - 1.8e-77 260.4 0.0 2.1e-77 260.2 0.0 1.1 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase C-terminal domain Ribosomal_L7Ae PF01248.26 KFM28124.1 - 5.1e-24 83.8 0.8 9.2e-24 83.0 0.8 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KFM28124.1 - 0.021 14.9 0.0 0.031 14.3 0.0 1.3 1 0 0 1 1 1 0 RNase P subunit Pop3 Sacchrp_dh_NADP PF03435.18 KFM28126.1 - 5e-16 59.1 0.0 9.6e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KFM28126.1 - 0.026 14.4 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Semialdhyde_dh PF01118.24 KFM28126.1 - 0.073 13.5 0.1 0.34 11.4 0.0 2.1 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 KFM28126.1 - 0.18 11.3 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFM28126.1 - 0.23 10.4 0.0 0.31 10.0 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Pkinase PF00069.25 KFM28127.1 - 1.1e-62 211.9 0.0 1.4e-62 211.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM28127.1 - 3.9e-47 160.7 0.0 5.6e-47 160.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFM28127.1 - 4.1e-08 32.4 0.0 7.6e-08 31.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFM28127.1 - 4.2e-05 23.0 0.2 0.00067 19.1 0.0 2.2 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 KFM28127.1 - 0.0055 16.3 0.0 0.035 13.7 0.0 2.0 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KFM28127.1 - 0.028 13.8 0.0 0.079 12.3 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Val_tRNA-synt_C PF10458.9 KFM28127.1 - 0.043 14.1 0.2 0.12 12.7 0.2 1.7 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm APH PF01636.23 KFM28127.1 - 0.05 13.5 0.0 0.05 13.5 0.0 3.0 3 2 0 3 3 3 0 Phosphotransferase enzyme family bZIP_1 PF00170.21 KFM28127.1 - 0.063 13.4 2.0 0.092 12.9 0.3 2.1 2 0 0 2 2 2 0 bZIP transcription factor Haspin_kinase PF12330.8 KFM28127.1 - 0.24 10.3 0.0 2.8 6.8 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain Totivirus_coat PF05518.11 KFM28127.1 - 0.32 9.0 0.0 0.32 9.0 0.0 2.6 3 0 0 3 3 3 0 Totivirus coat protein TSC22 PF01166.18 KFM28127.1 - 0.72 10.2 2.8 0.63 10.4 0.8 1.9 2 0 0 2 2 2 0 TSC-22/dip/bun family bZIP_2 PF07716.15 KFM28127.1 - 2.4 8.3 9.8 0.099 12.7 2.0 2.6 3 0 0 3 3 3 0 Basic region leucine zipper Metal_resist PF13801.6 KFM28127.1 - 4.8 7.4 22.3 0.11 12.7 6.0 3.8 3 1 2 5 5 5 0 Heavy-metal resistance NTP_transferase PF00483.23 KFM28128.1 - 1.7e-70 237.4 0.0 2.2e-70 237.0 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KFM28128.1 - 0.0024 18.3 0.0 0.0052 17.2 0.0 1.5 1 1 0 1 1 1 1 MobA-like NTP transferase domain BolA PF01722.18 KFM28129.1 - 5.4e-31 106.7 0.8 1.2e-30 105.6 0.1 2.0 2 0 0 2 2 2 1 BolA-like protein FH2 PF02181.23 KFM28129.1 - 1.6e-08 34.1 0.0 2.4e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain tRNA-synt_His PF13393.6 KFM28130.1 - 8.3e-42 143.5 0.0 1.2e-41 143.0 0.0 1.2 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.25 KFM28130.1 - 8.3e-07 29.1 0.0 1.1e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KFM28130.1 - 2.2e-05 24.5 0.0 4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Anticodon binding domain U-box PF04564.15 KFM28131.1 - 1.5e-16 60.3 0.0 2.6e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 U-box domain Rhomboid PF01694.22 KFM28131.1 - 6e-09 36.1 13.1 2.7e-08 33.9 13.1 2.1 1 1 0 1 1 1 1 Rhomboid family zf-Nse PF11789.8 KFM28131.1 - 0.0087 15.9 0.1 0.019 14.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Sugar_tr PF00083.24 KFM28133.1 - 9.1e-68 229.2 22.9 6.1e-37 127.5 3.9 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KFM28133.1 - 2e-16 59.9 43.8 6.1e-12 45.1 11.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily PaO PF08417.12 KFM28134.1 - 1e-11 44.8 0.0 2.1e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Pheophorbide a oxygenase Tim17 PF02466.19 KFM28135.1 - 3.2e-09 37.1 0.3 3.7e-09 36.9 0.3 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF3419 PF11899.8 KFM28137.1 - 1.5e-113 379.9 0.0 1.9e-113 379.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 KFM28137.1 - 6.2e-07 29.4 0.0 1.1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM28137.1 - 3.3e-06 27.7 0.1 3.4e-05 24.5 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFM28137.1 - 3.8e-06 26.4 0.0 7e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KFM28137.1 - 0.00018 21.3 0.0 0.0005 19.9 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 KFM28137.1 - 0.0015 19.3 0.0 0.0056 17.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM28137.1 - 0.012 15.4 0.0 0.032 14.0 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain MutS_V PF00488.21 KFM28138.1 - 1.8e-67 227.1 0.0 2.6e-67 226.5 0.0 1.2 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.20 KFM28138.1 - 8.5e-26 90.4 0.0 1.5e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.18 KFM28138.1 - 2.3e-17 63.9 0.0 3.8e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 MutS domain III TUDOR_5 PF18359.1 KFM28138.1 - 0.003 17.2 0.0 0.006 16.3 0.0 1.5 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 MutS_IV PF05190.18 KFM28138.1 - 0.003 17.9 0.0 0.0048 17.2 0.0 1.3 1 0 0 1 1 1 1 MutS family domain IV Agenet PF05641.12 KFM28138.1 - 0.082 13.4 1.5 0.14 12.6 0.4 1.9 2 0 0 2 2 2 0 Agenet domain AAA_23 PF13476.6 KFM28138.1 - 0.085 13.4 0.0 0.17 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain SelP_C PF04593.14 KFM28138.1 - 0.097 12.7 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Selenoprotein P, C terminal region Amidinotransf PF02274.17 KFM28138.1 - 0.2 10.7 0.0 0.33 10.0 0.0 1.2 1 0 0 1 1 1 0 Amidinotransferase CDC45 PF02724.14 KFM28138.1 - 2.3 6.4 6.0 3.4 5.8 6.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KFM28138.1 - 5.4 5.1 8.9 7.5 4.6 8.9 1.1 1 0 0 1 1 1 0 Nop14-like family Phosducin PF02114.16 KFM28139.1 - 1.2e-15 57.2 0.0 1.7e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Phosducin Ribophorin_I PF04597.14 KFM28140.1 - 1.1e-56 192.9 0.0 7e-46 157.3 0.0 2.2 1 1 1 2 2 2 2 Ribophorin I Glyco_tranf_2_3 PF13641.6 KFM28141.1 - 9.4e-21 74.8 0.0 1.4e-20 74.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KFM28141.1 - 3.8e-19 69.4 1.1 8.2e-19 68.3 1.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KFM28141.1 - 3.2e-12 46.6 0.0 5.3e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Cellulose_synt PF03552.14 KFM28141.1 - 0.04 12.4 0.9 0.058 11.9 0.9 1.1 1 0 0 1 1 1 0 Cellulose synthase DUF563 PF04577.14 KFM28142.1 - 2.1e-15 57.4 0.0 3.7e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Glucokinase PF02685.16 KFM28143.1 - 2.8e-83 279.6 0.0 4.6e-83 278.8 0.0 1.3 1 0 0 1 1 1 1 Glucokinase UvrD-helicase PF00580.21 KFM28143.1 - 2.1e-61 208.2 0.0 3.1e-61 207.6 0.0 1.1 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 KFM28143.1 - 1.2e-45 156.4 0.0 1.2e-23 84.1 0.0 2.2 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KFM28143.1 - 9.6e-34 116.8 0.6 2.4e-33 115.5 0.1 1.9 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 KFM28143.1 - 3.3e-08 33.2 0.1 1.4e-07 31.2 0.1 2.1 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_12 PF13087.6 KFM28143.1 - 0.00041 20.0 0.0 0.026 14.1 0.0 3.2 4 0 0 4 4 4 1 AAA domain Med15_fungi PF05397.12 KFM28143.1 - 0.0026 18.0 0.5 0.0053 17.0 0.5 1.4 1 0 0 1 1 1 1 Mediator complex subunit 15 Viral_helicase1 PF01443.18 KFM28143.1 - 0.0099 15.6 0.0 3.5 7.3 0.0 3.0 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 KFM28143.1 - 0.024 14.4 0.1 0.095 12.5 0.1 2.1 1 1 0 1 1 1 0 AAA domain Fer2 PF00111.27 KFM28144.1 - 8.8e-09 35.2 0.8 1.1e-08 34.9 0.8 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain MCR PF18509.1 KFM28144.1 - 0.06 12.9 0.2 0.12 12.0 0.2 1.5 1 0 0 1 1 1 0 Magnetochrome domain Pentapeptide_2 PF01469.18 KFM28145.1 - 0.018 14.9 18.6 0.018 14.9 18.6 1.6 2 0 0 2 2 2 0 Pentapeptide repeats (8 copies) TTL PF03133.15 KFM28146.1 - 1.1e-12 47.8 0.0 7.9e-11 41.6 0.0 2.4 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family p450 PF00067.22 KFM28148.1 - 2.4e-47 161.8 0.0 3.2e-47 161.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Radical_SAM PF04055.21 KFM28150.1 - 1.1e-12 48.6 0.0 3.9e-12 46.9 0.0 1.8 1 1 0 1 1 1 1 Radical SAM superfamily CDC50 PF03381.15 KFM28152.1 - 1.2e-60 205.4 0.0 5e-60 203.4 0.0 1.7 1 1 1 2 2 2 2 LEM3 (ligand-effect modulator 3) family / CDC50 family MCM PF00493.23 KFM28155.1 - 3.6e-100 333.7 0.0 5.7e-100 333.0 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 KFM28155.1 - 7e-28 96.9 2.7 1.6e-27 95.8 2.7 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 KFM28155.1 - 1.6e-27 95.8 0.6 1.9e-26 92.4 0.6 2.3 1 1 0 1 1 1 1 MCM OB domain MCM_N PF14551.6 KFM28155.1 - 8.1e-14 52.1 0.1 2.9e-13 50.3 0.1 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 KFM28155.1 - 2e-07 30.6 0.1 0.00012 21.6 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KFM28155.1 - 8.1e-07 29.1 0.0 3.3e-06 27.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KFM28155.1 - 0.0018 18.1 0.0 0.0084 16.0 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KFM28155.1 - 0.0093 15.7 0.0 2 8.1 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA PF00004.29 KFM28155.1 - 0.017 15.5 0.1 0.17 12.3 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFM28155.1 - 0.038 14.4 1.7 0.86 10.0 0.1 3.2 2 2 1 3 3 3 0 AAA ATPase domain PEP-utilizers PF00391.23 KFM28155.1 - 0.054 13.2 0.0 0.26 11.0 0.0 2.1 1 0 0 1 1 1 0 PEP-utilising enzyme, mobile domain NTPase_1 PF03266.15 KFM28155.1 - 0.11 12.4 0.1 2.9 7.8 0.1 2.3 1 1 1 2 2 2 0 NTPase DUF4778 PF16008.5 KFM28155.1 - 0.37 10.8 1.1 0.59 10.1 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4778) DEAD PF00270.29 KFM28156.1 - 3.6e-44 150.6 0.0 9.7e-44 149.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM28156.1 - 8.7e-25 87.2 0.0 2.6e-24 85.7 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KFM28156.1 - 8.3e-21 74.0 0.4 1.6e-20 73.1 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ERCC3_RAD25_C PF16203.5 KFM28156.1 - 0.00011 21.5 0.0 0.00029 20.1 0.0 1.7 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KFM28156.1 - 0.00019 21.5 0.0 0.00039 20.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Aminotran_5 PF00266.19 KFM28157.1 - 9.6e-54 182.7 0.0 1.1e-53 182.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Presenilin PF01080.17 KFM28158.1 - 5.4e-94 315.2 0.0 1.2e-93 314.0 0.0 1.5 1 1 0 1 1 1 1 Presenilin MFS_1 PF07690.16 KFM28159.1 - 2.3e-47 161.7 37.1 4.2e-45 154.2 25.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM28159.1 - 1.2e-17 64.0 2.5 1.2e-17 64.0 2.5 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 KFM28159.1 - 0.0019 17.1 2.0 0.0019 17.1 2.0 2.3 2 0 0 2 2 2 2 MFS_1 like family MFS_4 PF06779.14 KFM28159.1 - 0.0089 15.4 26.6 0.042 13.1 26.6 2.0 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 KFM28159.1 - 0.01 14.1 3.3 0.015 13.6 0.2 2.4 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family TRI12 PF06609.13 KFM28159.1 - 0.063 11.7 1.6 0.087 11.2 1.6 1.1 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Nucleoside_tran PF01733.18 KFM28159.1 - 1.3 8.3 3.4 1 8.7 1.6 1.6 2 0 0 2 2 2 0 Nucleoside transporter GST_N_2 PF13409.6 KFM28160.1 - 8.3e-16 58.0 0.0 1.9e-15 56.9 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFM28160.1 - 1.7e-11 44.0 0.1 4.1e-11 42.7 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFM28160.1 - 2.5e-10 40.4 0.1 8.3e-10 38.8 0.1 1.8 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFM28160.1 - 3.3e-05 24.0 0.2 7.6e-05 22.8 0.1 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KFM28160.1 - 0.00046 20.6 0.0 0.55 10.7 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 KFM28160.1 - 0.0062 16.3 0.1 0.012 15.4 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Lipase_GDSL_2 PF13472.6 KFM28166.1 - 1.1e-21 78.1 0.0 1.5e-21 77.6 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFM28166.1 - 3.5e-16 59.8 0.0 5.5e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase OCRE PF17780.1 KFM28167.1 - 8.1e-09 35.4 0.2 2e-07 30.9 0.0 2.2 2 0 0 2 2 2 1 OCRE domain DUF1611_N PF17396.2 KFM28167.1 - 0.019 15.2 0.1 0.061 13.6 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1611_N) Rossmann-like domain PRK PF00485.18 KFM28168.1 - 0.00012 21.9 0.0 0.00022 21.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 KFM28168.1 - 0.00034 21.1 0.0 0.00049 20.5 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.15 KFM28168.1 - 0.0094 15.9 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 1 NTPase MobB PF03205.14 KFM28168.1 - 0.0094 15.8 0.0 0.61 10.0 0.0 2.2 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 KFM28168.1 - 0.01 16.4 0.0 0.019 15.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 KFM28168.1 - 0.011 14.8 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 KFM28168.1 - 0.027 13.8 0.0 0.048 12.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 KFM28168.1 - 0.028 14.2 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 KFM28168.1 - 0.028 13.7 0.0 0.028 13.7 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain AAA_22 PF13401.6 KFM28168.1 - 0.056 13.7 0.0 0.078 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_35 PF14516.6 KFM28168.1 - 0.059 12.2 0.0 0.079 11.8 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain RNA_helicase PF00910.22 KFM28168.1 - 0.069 13.5 0.2 0.22 11.9 0.0 1.8 2 0 0 2 2 2 0 RNA helicase DUF815 PF05673.13 KFM28168.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NB-ARC PF00931.22 KFM28168.1 - 0.17 11.1 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Fe-S_biosyn PF01521.20 KFM28169.1 - 1.6e-11 44.4 0.0 1.8e-11 44.2 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Proteasome PF00227.26 KFM28171.1 - 4.3e-43 147.0 0.0 4.9e-43 146.8 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Cgr1 PF03879.14 KFM28172.1 - 0.0004 20.7 21.9 0.0004 20.7 21.9 2.0 2 0 0 2 2 2 1 Cgr1 family TSP_NTD PF17804.1 KFM28172.1 - 3.1 8.0 10.7 0.47 10.7 6.7 1.6 2 0 0 2 2 2 0 Tail specific protease N-terminal domain RNA_pol_Rbc25 PF08292.12 KFM28172.1 - 3.2 8.0 7.4 0.68 10.2 3.3 1.8 1 1 0 2 2 2 0 RNA polymerase III subunit Rpc25 YccV-like PF08755.11 KFM28174.1 - 8.3e-20 71.1 0.0 1.4e-19 70.4 0.0 1.4 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like EAP30 PF04157.16 KFM28175.1 - 0.12 11.6 0.0 0.6 9.4 0.0 2.0 2 0 0 2 2 2 0 EAP30/Vps36 family Prefoldin PF02996.17 KFM28176.1 - 1.4e-19 70.1 1.7 2.1e-19 69.6 1.7 1.3 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 KFM28176.1 - 0.054 13.5 1.5 1.4 8.9 0.0 2.4 2 1 0 2 2 2 0 Prefoldin subunit NAD_binding_1 PF00175.21 KFM28177.1 - 4.8e-09 36.8 0.0 8.3e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain GTP1_OBG PF01018.22 KFM28178.1 - 2.5e-48 163.6 6.5 4.3e-48 162.8 6.5 1.4 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 KFM28178.1 - 2.6e-23 82.3 0.0 4e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF1967 PF09269.11 KFM28178.1 - 7.3e-20 70.7 0.0 1.1e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1967) FeoB_N PF02421.18 KFM28178.1 - 2.1e-08 33.9 0.0 4.1e-08 32.9 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_30 PF13604.6 KFM28178.1 - 0.0033 17.2 1.8 0.21 11.3 0.1 2.9 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 KFM28178.1 - 0.15 12.6 0.0 0.28 11.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 KFM28178.1 - 0.18 12.1 0.0 0.38 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 KFM28178.1 - 0.21 11.1 0.0 13 5.3 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FAD_binding_3 PF01494.19 KFM28180.1 - 4.2e-05 23.0 0.4 0.00015 21.1 0.0 1.9 2 1 0 2 2 2 1 FAD binding domain SE PF08491.10 KFM28180.1 - 0.0003 19.9 0.0 0.00044 19.4 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Trp_halogenase PF04820.14 KFM28180.1 - 0.23 10.3 0.0 0.38 9.5 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Myb_DNA-binding PF00249.31 KFM28181.1 - 7.9e-28 96.4 3.8 1.3e-15 57.2 1.0 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFM28181.1 - 3.9e-20 71.9 0.5 1.4e-13 50.9 0.1 2.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KFM28181.1 - 0.00048 20.0 0.0 0.005 16.7 0.0 2.0 1 1 1 2 2 2 1 Myb DNA-binding like PRMT5 PF05185.16 KFM28183.1 - 1.8e-67 226.5 0.0 2.5e-67 226.0 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_TIM PF17285.2 KFM28183.1 - 2.3e-53 181.0 0.0 3.3e-53 180.5 0.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5_C PF17286.2 KFM28183.1 - 7.2e-50 169.3 0.1 1.3e-49 168.4 0.1 1.5 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Methyltransf_25 PF13649.6 KFM28183.1 - 1.5e-05 25.6 0.0 3.5e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFM28183.1 - 0.0017 19.0 0.0 0.0036 17.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 KFM28183.1 - 0.0088 15.8 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein RcbX PF02341.15 KFM28184.1 - 1.5e-08 34.9 0.2 5.7e-08 33.0 0.2 1.8 1 1 0 1 1 1 1 RbcX protein Profilin PF00235.19 KFM28185.1 - 4.7e-05 23.7 0.0 5.2e-05 23.5 0.0 1.0 1 0 0 1 1 1 1 Profilin Got1 PF04178.12 KFM28186.1 - 2.3e-23 82.8 17.0 1.1e-11 45.1 3.0 2.4 1 1 1 2 2 2 2 Got1/Sft2-like family DUF1673 PF07895.11 KFM28186.1 - 0.87 9.2 3.8 0.76 9.4 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) Phage_holin_3_6 PF07332.11 KFM28186.1 - 9.7 6.3 17.6 0.24 11.4 5.4 2.3 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III LRR_6 PF13516.6 KFM28187.1 - 0.00093 19.1 0.0 0.59 10.3 0.0 3.0 2 0 0 2 2 2 2 Leucine Rich repeat Ntox14 PF15522.6 KFM28187.1 - 0.073 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Novel toxin 14 Med27 PF11571.8 KFM28188.1 - 5.5e-08 33.1 0.0 1e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit 27 FAM131 PF15010.6 KFM28188.1 - 0.0007 19.6 0.0 0.0014 18.6 0.0 1.4 1 1 0 1 1 1 1 Putative cell signalling Cyt-b5 PF00173.28 KFM28189.1 - 1.2e-21 76.6 0.2 2e-21 75.9 0.2 1.4 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TPT PF03151.16 KFM28191.1 - 2.1e-112 375.2 18.5 2.5e-112 375.0 18.5 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KFM28191.1 - 2.1e-15 57.1 27.8 1.2e-10 41.7 11.4 2.4 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KFM28191.1 - 0.0028 16.9 17.0 0.0047 16.2 17.0 1.4 1 1 0 1 1 1 1 UAA transporter family DUF676 PF05057.14 KFM28191.1 - 0.41 10.1 1.9 1.2 8.6 0.1 2.1 2 0 0 2 2 2 0 Putative serine esterase (DUF676) NMD3 PF04981.13 KFM28192.1 - 9.6e-72 241.4 7.0 1.3e-71 240.9 7.0 1.2 1 0 0 1 1 1 1 NMD3 family DUF1289 PF06945.13 KFM28192.1 - 0.0089 15.8 3.8 0.12 12.2 0.2 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1289) Nif11 PF07862.11 KFM28192.1 - 0.034 14.4 0.7 0.094 13.0 0.7 1.8 1 0 0 1 1 1 0 Nif11 domain eIF-5_eIF-2B PF01873.17 KFM28192.1 - 0.95 9.4 4.4 1.2 9.1 0.1 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 TackOD1 PF18551.1 KFM28192.1 - 4.9 6.8 8.9 11 5.6 3.7 2.3 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 Ribosomal_L22 PF00237.19 KFM28194.1 - 8.8e-40 135.1 0.1 1.6e-39 134.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e U3_snoRNA_assoc PF08297.11 KFM28195.1 - 0.0078 16.9 15.4 0.012 16.3 0.1 2.5 2 1 0 2 2 2 1 U3 snoRNA associated CDC45 PF02724.14 KFM28195.1 - 0.49 8.6 10.4 0.57 8.4 10.4 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2151 PF10221.9 KFM28195.1 - 1.3 7.5 4.3 1.6 7.2 4.3 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator OST-HTH PF12872.7 KFM28196.1 - 0.088 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 OST-HTH/LOTUS domain DEC-1_N PF04625.13 KFM28196.1 - 0.8 8.7 7.6 1.2 8.1 7.6 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region AA_kinase PF00696.28 KFM28197.1 - 1e-36 126.8 0.3 1.5e-36 126.2 0.3 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 KFM28197.1 - 7.5e-19 67.5 0.1 2.1e-18 66.0 0.1 1.8 1 0 0 1 1 1 1 PUA domain TMEM40 PF15817.5 KFM28197.1 - 0.0089 15.8 0.0 0.034 13.9 0.0 1.9 2 0 0 2 2 2 1 Transmembrane protein 40 family PUA_3 PF17785.1 KFM28197.1 - 0.024 14.5 0.0 0.049 13.5 0.0 1.5 1 0 0 1 1 1 0 PUA-like domain RRM_1 PF00076.22 KFM28198.1 - 1.8e-22 78.9 0.1 5e-12 45.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 KFM28198.1 - 8.2e-20 71.7 1.1 1.8e-18 67.4 0.0 2.6 2 1 0 2 2 2 1 linker between RRM2 and RRM3 domains in RBM39 protein Ribosomal_L4 PF00573.22 KFM28200.1 - 8e-56 188.8 0.1 1.6e-55 187.8 0.1 1.5 1 1 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_S30 PF04758.14 KFM28201.1 - 5.4e-28 97.0 5.6 6.6e-28 96.7 5.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S30 SQS_PSY PF00494.19 KFM28202.1 - 2e-26 93.1 1.4 2.4e-26 92.8 1.4 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase LRR_4 PF12799.7 KFM28204.1 - 4.7e-08 33.2 0.2 3.5 8.2 0.0 6.2 6 1 1 7 7 7 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFM28204.1 - 0.0089 16.0 4.1 16 5.9 0.0 5.9 6 0 0 6 6 6 1 Leucine Rich repeat LRR_8 PF13855.6 KFM28204.1 - 0.013 15.3 13.7 1.9 8.3 0.0 6.9 7 2 0 7 7 7 0 Leucine rich repeat LRR_1 PF00560.33 KFM28204.1 - 0.16 12.6 6.1 9 7.3 0.2 5.4 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_4 PF12799.7 KFM28205.1 - 0.017 15.6 7.6 2.1 8.9 0.1 6.5 5 3 5 10 10 10 0 Leucine Rich repeats (2 copies) HrpB1_HrpK PF09613.10 KFM28205.1 - 0.036 13.7 0.3 0.26 10.9 0.0 2.3 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) LRR_8 PF13855.6 KFM28205.1 - 1 9.1 7.7 57 3.6 0.2 5.3 4 2 1 5 5 5 0 Leucine rich repeat tRNA_U5-meth_tr PF05958.11 KFM28206.1 - 1.4e-85 287.5 0.0 2.8e-44 151.5 0.0 3.0 1 1 2 3 3 3 3 tRNA (Uracil-5-)-methyltransferase Methyltransf_25 PF13649.6 KFM28206.1 - 1.4e-06 28.9 0.1 7.1e-06 26.7 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFM28206.1 - 7.6e-05 23.3 0.1 0.0008 20.0 0.1 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM28206.1 - 0.00018 21.3 0.0 0.00048 20.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KFM28206.1 - 0.0011 18.5 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 KFM28206.1 - 0.0016 18.0 0.0 0.0026 17.4 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_12 PF08242.12 KFM28206.1 - 0.0026 18.4 0.0 0.0095 16.7 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 KFM28206.1 - 0.079 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase COQ9 PF08511.11 KFM28207.1 - 1.5e-08 34.3 0.0 2.4e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 COQ9 TetR_C_23 PF17931.1 KFM28207.1 - 0.089 12.9 0.0 0.14 12.2 0.0 1.4 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain COQ9 PF08511.11 KFM28208.1 - 0.0076 16.0 0.1 0.015 15.1 0.1 1.5 1 0 0 1 1 1 1 COQ9 PAP_fibrillin PF04755.12 KFM28209.1 - 4.4e-12 46.4 0.0 7.8e-12 45.6 0.0 1.4 1 1 0 1 1 1 1 PAP_fibrillin SOUL PF04832.12 KFM28210.1 - 1.4e-37 129.5 0.1 1.8e-35 122.6 0.1 2.0 1 1 0 1 1 1 1 SOUL heme-binding protein SLIDE PF09111.10 KFM28212.1 - 7.3e-44 148.4 0.9 1.5e-43 147.4 0.5 1.7 2 0 0 2 2 2 1 SLIDE Myb_DNA-binding PF00249.31 KFM28212.1 - 2.8e-10 40.2 1.6 0.0003 20.9 0.1 3.2 3 0 0 3 3 3 2 Myb-like DNA-binding domain HAND PF09110.11 KFM28212.1 - 0.00027 21.7 0.8 0.00027 21.7 0.8 2.2 2 0 0 2 2 2 1 HAND DUF1086 PF06461.11 KFM28212.1 - 0.0011 18.8 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1086) Clathrin PF00637.20 KFM28213.1 - 4.2e-19 68.8 0.0 4.9e-19 68.6 0.0 1.0 1 0 0 1 1 1 1 Region in Clathrin and VPS SNF2_N PF00176.23 KFM28214.1 - 3.1e-75 253.1 0.1 5.3e-75 252.3 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFM28214.1 - 9.7e-20 71.0 0.0 1.4e-18 67.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM28214.1 - 3.1e-10 40.3 0.0 1.1e-09 38.5 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFM28214.1 - 5.6e-07 29.5 0.0 1.6e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase DBINO PF13892.6 KFM28214.1 - 2.5e-05 24.6 2.1 6.6e-05 23.3 2.1 1.6 1 0 0 1 1 1 1 DNA-binding domain HDA2-3 PF11496.8 KFM28214.1 - 0.00011 21.5 0.0 0.00028 20.2 0.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 KFM28214.1 - 0.00084 19.1 0.0 0.0017 18.0 0.0 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_14 PF13173.6 KFM28214.1 - 0.025 14.6 0.0 0.052 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain RabGAP-TBC PF00566.18 KFM28215.1 - 2.4e-43 148.3 0.0 3.4e-43 147.8 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ribosomal_L27 PF01016.19 KFM28216.1 - 7.1e-24 83.6 0.1 7.9e-24 83.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal L27 protein VASt PF16016.5 KFM28217.1 - 6.9e-32 111.0 3.8 1.5e-31 109.9 2.6 2.0 2 0 0 2 2 2 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 KFM28217.1 - 1.8e-16 60.0 0.6 3.3e-16 59.2 0.2 1.6 2 0 0 2 2 2 1 GRAM domain GDP_Man_Dehyd PF16363.5 KFM28219.1 - 4.1e-64 217.1 0.0 5.9e-64 216.6 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KFM28219.1 - 4.5e-55 186.7 0.2 9.8e-55 185.6 0.1 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DEAD PF00270.29 KFM28219.1 - 4.8e-46 156.7 0.0 1.4e-45 155.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM28219.1 - 2.9e-24 85.6 0.0 1.5e-23 83.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain 3Beta_HSD PF01073.19 KFM28219.1 - 1e-17 64.1 0.1 1.5e-17 63.6 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KFM28219.1 - 1.8e-17 63.5 0.1 5.4e-16 58.6 0.1 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KFM28219.1 - 4.4e-15 55.5 0.3 6.8e-14 51.7 0.3 2.2 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 KFM28219.1 - 1.3e-12 47.4 0.0 1.9e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KFM28219.1 - 0.0013 18.6 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding ResIII PF04851.15 KFM28219.1 - 0.0097 15.9 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KFM28219.1 - 0.013 15.8 0.0 10 6.4 0.0 3.5 3 0 0 3 3 3 0 AAA domain NmrA PF05368.13 KFM28219.1 - 0.052 13.1 0.0 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 NmrA-like family adh_short PF00106.25 KFM28219.1 - 0.15 11.5 1.4 15 5.0 0.2 3.3 4 0 0 4 4 4 0 short chain dehydrogenase CG-1 PF03859.16 KFM28220.1 - 8.9e-37 125.4 0.1 1.8e-36 124.4 0.1 1.5 1 0 0 1 1 1 1 CG-1 domain DUF3336 PF11815.8 KFM28220.1 - 1e-12 48.0 0.3 3.2e-12 46.3 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KFM28220.1 - 4.3e-11 43.4 2.6 2e-10 41.2 2.6 2.2 1 1 0 1 1 1 1 Patatin-like phospholipase TIG PF01833.24 KFM28220.1 - 0.00036 20.6 0.0 0.00067 19.7 0.0 1.5 1 0 0 1 1 1 1 IPT/TIG domain DUF3253 PF11625.8 KFM28220.1 - 0.39 11.0 1.8 0.86 9.9 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3253) FtsJ PF01728.19 KFM28221.1 - 2.3e-10 40.9 0.0 4.4e-10 39.9 0.0 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_24 PF13578.6 KFM28221.1 - 0.0083 17.1 0.0 0.023 15.7 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM28221.1 - 0.0084 16.0 0.0 0.038 13.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Prim-Pol PF09250.11 KFM28221.1 - 0.042 14.2 0.1 0.065 13.6 0.1 1.4 1 0 0 1 1 1 0 Bifunctional DNA primase/polymerase, N-terminal Methyltransf_25 PF13649.6 KFM28221.1 - 0.047 14.4 0.0 0.097 13.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Sel1 PF08238.12 KFM28222.1 - 1.6e-05 25.4 0.3 3.1e-05 24.5 0.3 1.5 1 0 0 1 1 1 1 Sel1 repeat TFIIS_C PF01096.18 KFM28223.1 - 4.3e-12 45.7 1.7 4.3e-12 45.7 1.7 2.3 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KFM28223.1 - 5.2e-12 45.4 5.4 6.1e-12 45.2 0.2 2.6 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 KFM28223.1 - 0.0039 17.1 4.4 0.016 15.1 0.5 2.5 2 0 0 2 2 2 1 Transposase zinc-ribbon domain Ribosomal_S27e PF01667.17 KFM28223.1 - 0.012 15.3 1.7 0.012 15.3 1.7 1.9 2 1 0 2 2 2 0 Ribosomal protein S27 PH PF00169.29 KFM28223.1 - 0.061 13.8 0.0 0.18 12.3 0.0 1.6 1 1 0 1 1 1 0 PH domain DUF2387 PF09526.10 KFM28223.1 - 0.085 13.0 4.2 0.34 11.1 0.5 2.2 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) eIF-5_eIF-2B PF01873.17 KFM28223.1 - 0.23 11.3 2.9 0.17 11.8 0.6 1.8 2 0 0 2 2 2 0 Domain found in IF2B/IF5 zinc_ribbon_4 PF13717.6 KFM28223.1 - 0.44 10.5 8.7 2.8 7.9 0.1 2.8 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_10 PF10058.9 KFM28223.1 - 0.59 9.9 5.7 3.9 7.3 1.0 2.4 2 1 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein DUF4379 PF14311.6 KFM28223.1 - 1.8 9.0 7.9 3.2 8.2 0.0 3.3 3 1 0 3 3 3 0 Probable Zinc-ribbon domain CENP-F_N PF10481.9 KFM28224.1 - 0.024 14.3 0.4 0.042 13.5 0.3 1.3 1 1 0 1 1 1 0 Cenp-F N-terminal domain DiS_P_DiS PF06750.13 KFM28225.1 - 0.013 15.6 2.1 4.2 7.6 0.0 2.5 2 1 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain Melibiase_2 PF16499.5 KFM28226.1 - 1.4e-70 237.7 0.0 2e-70 237.2 0.0 1.2 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 KFM28226.1 - 7.4e-17 61.2 0.0 1.8e-16 60.0 0.0 1.7 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KFM28226.1 - 1.2e-08 34.3 0.0 2e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Melibiase Melibiase_2_C PF17450.2 KFM28226.1 - 0.02 15.1 0.0 0.044 14.0 0.0 1.5 1 0 0 1 1 1 0 Alpha galactosidase A C-terminal beta sandwich domain zf-RanBP PF00641.18 KFM28227.1 - 1.3e-10 40.3 2.9 1.8e-10 39.9 2.9 1.1 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF35_N PF12172.8 KFM28227.1 - 0.027 14.4 1.5 0.027 14.4 1.5 1.8 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-C5HC2 PF02928.16 KFM28227.1 - 0.37 11.2 2.5 0.53 10.7 2.5 1.2 1 0 0 1 1 1 0 C5HC2 zinc finger Ribosomal_L15e PF00827.17 KFM28228.1 - 2.5e-93 311.1 3.6 3.2e-93 310.8 3.6 1.1 1 0 0 1 1 1 1 Ribosomal L15 EI24 PF07264.11 KFM28228.1 - 4e-25 89.1 12.8 6.2e-25 88.5 12.8 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) HhH-GPD PF00730.25 KFM28229.1 - 1.9e-17 63.7 0.0 2.5e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KFM28229.1 - 1.7e-07 30.7 0.1 4.4e-07 29.4 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix motif DUF2400 PF09674.10 KFM28229.1 - 0.15 12.0 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) COG5 PF10392.9 KFM28230.1 - 1e-14 54.8 0.0 2.5e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 Golgi transport complex subunit 5 COG2 PF06148.11 KFM28230.1 - 0.00013 22.1 0.0 0.00027 21.0 0.0 1.5 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Hpt PF01627.23 KFM28231.1 - 2.9e-10 40.3 1.3 4.3e-10 39.7 1.3 1.3 1 0 0 1 1 1 1 Hpt domain AAA_2 PF07724.14 KFM28232.1 - 2.5e-59 200.2 0.1 1.6e-55 187.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KFM28232.1 - 2.4e-32 111.0 8.3 3.4e-32 110.4 1.0 2.6 2 0 0 2 2 2 1 AAA lid domain AAA PF00004.29 KFM28232.1 - 9e-27 94.1 0.1 5.3e-14 52.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Clp_N PF02861.20 KFM28232.1 - 2.6e-25 88.3 0.9 2.6e-12 46.7 0.0 3.2 3 0 0 3 3 2 2 Clp amino terminal domain, pathogenicity island component ClpB_D2-small PF10431.9 KFM28232.1 - 1e-23 83.1 2.7 1.5e-23 82.6 0.5 2.6 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KFM28232.1 - 5.2e-18 65.4 0.9 3.7e-12 46.4 0.0 3.7 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFM28232.1 - 8.8e-10 39.2 11.0 0.00012 22.5 0.0 4.6 4 3 1 6 6 4 2 AAA ATPase domain Sigma54_activat PF00158.26 KFM28232.1 - 1.2e-09 38.0 0.1 5e-06 26.3 0.0 2.7 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 KFM28232.1 - 1.3e-08 35.2 4.3 0.0035 17.6 0.0 4.8 3 2 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 KFM28232.1 - 2e-07 30.9 0.0 0.017 14.8 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 KFM28232.1 - 1.3e-06 29.0 0.1 0.035 14.7 0.0 3.3 3 0 0 3 3 3 2 AAA domain RuvB_N PF05496.12 KFM28232.1 - 4.1e-06 26.6 1.4 0.17 11.6 0.0 3.9 3 1 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 KFM28232.1 - 7.9e-06 25.4 0.4 0.92 8.8 0.2 3.6 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI TniB PF05621.11 KFM28232.1 - 9.7e-06 25.1 0.0 0.01 15.2 0.0 3.9 3 1 0 3 3 3 1 Bacterial TniB protein AAA_7 PF12775.7 KFM28232.1 - 2.9e-05 23.7 0.0 0.013 15.1 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_14 PF13173.6 KFM28232.1 - 6.3e-05 23.0 0.0 0.41 10.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KFM28232.1 - 0.00011 21.6 0.0 0.034 13.4 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin ATPase_2 PF01637.18 KFM28232.1 - 0.00012 22.1 0.6 9.4 6.1 0.0 4.1 3 1 1 4 4 4 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 KFM28232.1 - 0.0002 21.5 0.0 0.45 10.7 0.0 3.1 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KFM28232.1 - 0.0002 21.7 0.5 0.48 10.8 0.0 2.9 3 0 0 3 3 2 2 RNA helicase NACHT PF05729.12 KFM28232.1 - 0.00031 20.7 0.1 0.28 11.1 0.0 3.0 2 1 0 2 2 2 1 NACHT domain FlxA PF14282.6 KFM28232.1 - 0.00035 20.5 2.4 0.00071 19.5 2.4 1.4 1 0 0 1 1 1 1 FlxA-like protein AAA_28 PF13521.6 KFM28232.1 - 0.00046 20.5 2.3 0.93 9.7 0.0 3.9 3 1 0 3 3 3 1 AAA domain Roc PF08477.13 KFM28232.1 - 0.0006 20.0 0.0 0.25 11.6 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 KFM28232.1 - 0.0007 19.4 0.0 0.65 9.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 KFM28232.1 - 0.0019 18.2 0.0 1.7 8.7 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 KFM28232.1 - 0.0037 17.2 0.0 1.1 9.1 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase AAA_3 PF07726.11 KFM28232.1 - 0.005 16.7 0.4 1.7 8.5 0.1 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 KFM28232.1 - 0.0062 16.5 0.0 1.2 9.1 0.0 3.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit ABC_tran PF00005.27 KFM28232.1 - 0.0083 16.6 0.8 0.94 10.0 0.0 3.3 3 0 0 3 3 3 1 ABC transporter TIP49 PF06068.13 KFM28232.1 - 0.009 15.2 0.4 1.6 7.8 0.1 3.0 2 1 1 3 3 3 1 TIP49 P-loop domain DNA_pol3_delta2 PF13177.6 KFM28232.1 - 0.02 14.7 0.0 0.62 9.8 0.0 2.9 2 1 0 2 2 2 0 DNA polymerase III, delta subunit AAA_25 PF13481.6 KFM28232.1 - 0.023 14.3 2.9 0.82 9.2 0.1 3.7 4 1 0 4 4 3 0 AAA domain Torsin PF06309.11 KFM28232.1 - 0.028 14.5 0.0 0.17 12.0 0.0 2.1 2 0 0 2 2 2 0 Torsin PduV-EutP PF10662.9 KFM28232.1 - 0.058 13.1 0.0 0.72 9.6 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.17 KFM28232.1 - 0.065 13.3 2.3 0.59 10.2 0.0 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_19 PF13245.6 KFM28232.1 - 0.11 12.8 0.5 2.4 8.5 0.0 3.0 2 2 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KFM28232.1 - 0.26 11.7 2.3 14 6.1 0.0 3.2 3 0 0 3 3 2 0 AAA domain AAA_23 PF13476.6 KFM28232.1 - 4.7 7.7 5.3 36 4.8 0.0 3.0 2 1 0 2 2 2 0 AAA domain CLTH PF10607.9 KFM28233.1 - 1.4e-31 109.4 1.3 1.9e-31 108.9 1.3 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KFM28233.1 - 6.8e-08 32.2 0.2 1.2e-07 31.4 0.2 1.4 1 0 0 1 1 1 1 LisH TPR_14 PF13428.6 KFM28233.1 - 0.21 12.5 3.8 1.2 10.1 0.4 3.1 3 1 1 4 4 4 0 Tetratricopeptide repeat Calmodulin_bind PF07887.11 KFM28234.1 - 7.9e-16 58.2 0.0 9e-15 54.7 0.0 2.4 1 1 0 1 1 1 1 Calmodulin binding protein-like MS_channel PF00924.18 KFM28235.1 - 6.9e-28 97.6 3.9 6.9e-28 97.6 3.9 2.3 2 1 0 2 2 2 1 Mechanosensitive ion channel TB2_DP1_HVA22 PF03134.19 KFM28236.1 - 2e-14 53.3 5.3 3.7e-14 52.4 5.3 1.5 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Peptidase_M22 PF00814.25 KFM28237.1 - 2.9e-64 217.4 5.4 9.9e-62 209.1 5.6 2.4 1 1 0 1 1 1 1 Glycoprotease family Ribosomal_S11 PF00411.19 KFM28237.1 - 0.00095 19.5 1.6 1.5 9.3 0.1 2.6 2 0 0 2 2 2 2 Ribosomal protein S11 SAND PF01342.21 KFM28238.1 - 1.9e-23 82.0 0.2 2.3e-09 36.8 0.1 3.7 4 0 0 4 4 4 3 SAND domain SET PF00856.28 KFM28238.1 - 9.4e-16 58.7 0.4 2.4e-15 57.3 0.0 2.0 2 0 0 2 2 2 1 SET domain zf-HC5HC2H PF13771.6 KFM28238.1 - 2.5e-13 50.1 0.6 2.5e-13 50.1 0.6 2.6 2 1 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KFM28238.1 - 2.8e-13 50.0 2.0 2.8e-13 50.0 2.0 1.9 2 0 0 2 2 2 1 PHD-zinc-finger like domain Zf_RING PF16744.5 KFM28238.1 - 0.063 13.4 3.0 0.22 11.6 3.0 1.9 1 0 0 1 1 1 0 KIAA1045 RING finger HMG_box PF00505.19 KFM28238.1 - 0.063 13.7 0.2 0.12 12.8 0.2 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box PHD PF00628.29 KFM28238.1 - 0.065 13.1 20.2 0.14 12.1 3.7 3.4 3 0 0 3 3 3 0 PHD-finger Jas PF16135.5 KFM28238.1 - 0.15 12.3 1.5 2.1 8.6 1.2 2.8 2 0 0 2 2 2 0 TPL-binding domain in jasmonate signalling PHD PF00628.29 KFM28239.1 - 1.1e-10 41.2 10.9 3.1e-08 33.4 1.9 2.2 2 0 0 2 2 2 2 PHD-finger zf-HC5HC2H PF13771.6 KFM28239.1 - 2.9e-07 30.6 1.4 2.9e-07 30.6 1.4 2.2 1 1 1 2 2 2 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KFM28239.1 - 1.7e-06 27.5 0.6 1.7e-06 27.5 0.6 2.7 3 0 0 3 3 3 1 PHD-finger zf-HC5HC2H_2 PF13832.6 KFM28239.1 - 2e-06 27.9 10.6 2.2e-06 27.8 5.9 2.1 1 1 1 2 2 2 1 PHD-zinc-finger like domain C1_1 PF00130.22 KFM28239.1 - 6.9e-06 25.9 5.3 4.5e-05 23.2 0.7 2.2 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KFM28239.1 - 0.0026 18.0 10.2 0.092 13.1 2.3 2.3 2 0 0 2 2 2 2 C1 domain Prok-RING_1 PF14446.6 KFM28239.1 - 0.0031 17.4 11.2 0.0082 16.1 4.4 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-RING-like PF08746.11 KFM28239.1 - 0.0039 17.5 8.0 0.36 11.2 0.4 2.3 2 0 0 2 2 2 2 RING-like domain zf-RING_2 PF13639.6 KFM28239.1 - 0.048 14.0 7.6 1.3 9.4 1.4 2.3 2 0 0 2 2 2 0 Ring finger domain zf-PHD-like PF15446.6 KFM28239.1 - 0.52 9.9 11.4 0.13 11.9 1.3 2.2 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-RRPl_C4 PF17026.5 KFM28239.1 - 0.79 9.8 2.6 1.1 9.3 2.6 1.2 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type Zn_ribbon_17 PF17120.5 KFM28239.1 - 0.97 9.1 8.6 1.2 8.8 1.2 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-UDP PF14569.6 KFM28239.1 - 4.6 7.4 8.0 0.62 10.2 1.8 2.1 2 0 0 2 2 2 0 Zinc-binding RING-finger PHD_4 PF16866.5 KFM28239.1 - 5.8 7.1 10.2 1 9.5 1.0 3.0 2 1 0 2 2 2 0 PHD-finger ER_lumen_recept PF00810.18 KFM28240.1 - 1.7e-52 178.1 11.9 2.5e-52 177.6 11.9 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KFM28240.1 - 0.0046 16.7 6.7 0.19 11.5 0.4 3.1 3 0 0 3 3 3 2 PQ loop repeat SpoIIM PF01944.17 KFM28240.1 - 0.012 15.6 0.7 0.025 14.6 0.7 1.6 1 0 0 1 1 1 0 Stage II sporulation protein M ATP_bind_3 PF01171.20 KFM28241.1 - 0.064 13.0 0.4 0.25 11.1 0.4 2.0 1 1 0 1 1 1 0 PP-loop family SAM_1 PF00536.30 KFM28242.1 - 2.7e-07 30.9 0.0 5.6e-07 29.9 0.0 1.5 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFM28242.1 - 1.7e-05 24.8 0.0 2.8e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF1127 PF06568.11 KFM28242.1 - 0.55 10.0 0.1 0.55 10.0 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1127) Pyridoxal_deC PF00282.19 KFM28243.1 - 1.3e-21 76.7 0.0 3.7e-21 75.3 0.0 1.7 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KFM28243.1 - 0.022 13.8 0.0 0.049 12.6 0.0 1.4 1 1 0 1 1 1 0 Aminotransferase class-V DUF3700 PF12481.8 KFM28244.1 - 4.7e-10 39.3 0.0 6.3e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Aluminium induced protein GATase_7 PF13537.6 KFM28244.1 - 2.6e-09 37.1 0.0 4.4e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KFM28244.1 - 1.1e-05 25.6 0.0 1.6e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase domain GCV_H PF01597.19 KFM28245.1 - 3.6e-45 152.8 0.2 4.3e-45 152.5 0.2 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 KFM28245.1 - 0.023 14.6 0.1 0.04 13.9 0.1 1.4 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.22 KFM28245.1 - 0.04 13.7 0.1 0.07 13.0 0.1 1.4 1 0 0 1 1 1 0 Biotin-requiring enzyme DUF1126 PF06565.12 KFM28246.1 - 1.4e-56 188.8 0.0 2.4e-19 69.1 0.0 3.3 3 0 0 3 3 3 3 DUF1126 PH-like domain bZIP_2 PF07716.15 KFM28247.1 - 0.3 11.2 1.5 0.43 10.7 1.5 1.2 1 0 0 1 1 1 0 Basic region leucine zipper UPF0183 PF03676.14 KFM28248.1 - 2.4e-45 155.5 0.0 4.7e-44 151.3 0.0 2.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0183) OrfB_Zn_ribbon PF07282.11 KFM28249.1 - 0.0054 16.6 6.9 0.029 14.3 6.9 2.1 1 1 0 1 1 1 1 Putative transposase DNA-binding domain OTT_1508_deam PF14441.6 KFM28249.1 - 0.048 13.7 0.9 0.1 12.7 0.9 1.4 1 0 0 1 1 1 0 OTT_1508-like deaminase ADH_N PF08240.12 KFM28250.1 - 3.2e-26 91.3 4.1 6e-26 90.5 4.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFM28250.1 - 2e-22 79.6 0.0 4.2e-22 78.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFM28250.1 - 4.2e-06 27.9 0.0 6.7e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KFM28250.1 - 9.5e-06 25.1 0.1 1.9e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KFM28250.1 - 5.4e-05 22.6 0.0 9.4e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KFM28250.1 - 0.0076 16.4 0.1 0.013 15.7 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KFM28250.1 - 0.037 13.9 0.1 0.073 13.0 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CBM_20 PF00686.19 KFM28251.1 - 7.9e-08 32.1 0.0 1.9e-07 30.9 0.0 1.6 1 1 0 1 1 1 1 Starch binding domain A_thal_3526 PF09713.10 KFM28252.1 - 1.5e-23 82.7 0.1 2.3e-23 82.2 0.1 1.3 1 0 0 1 1 1 1 Plant protein 1589 of unknown function (A_thal_3526) X PF00739.19 KFM28252.1 - 0.022 14.9 0.4 0.043 13.9 0.4 1.5 1 0 0 1 1 1 0 Trans-activation protein X NARP1 PF12569.8 KFM28253.1 - 2.7e-152 508.3 0.5 1.2e-151 506.2 0.1 1.9 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 KFM28253.1 - 9.3e-10 37.9 14.6 0.022 14.9 0.0 8.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFM28253.1 - 2.4e-09 36.7 0.1 0.011 15.8 0.0 6.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFM28253.1 - 5.7e-09 35.4 0.8 0.00098 18.8 0.1 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFM28253.1 - 5.8e-06 26.0 0.9 0.37 10.9 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFM28253.1 - 1.2e-05 24.8 5.1 0.0061 16.2 0.0 4.7 5 0 0 5 5 5 1 TPR repeat TPR_14 PF13428.6 KFM28253.1 - 0.00047 20.7 67.8 0.36 11.8 0.5 12.4 9 4 6 15 15 15 5 Tetratricopeptide repeat TPR_19 PF14559.6 KFM28253.1 - 0.017 15.6 0.1 0.07 13.6 0.1 9.1 7 2 3 10 10 10 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFM28253.1 - 0.085 13.3 8.7 23 5.7 0.1 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat CCDC53 PF10152.9 KFM28253.1 - 2.5 8.5 4.3 5.2 7.5 4.3 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Rad51 PF08423.11 KFM28254.1 - 9.8e-92 306.8 0.0 1.4e-91 306.3 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 KFM28254.1 - 6.5e-08 32.4 0.0 8.6e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 KFM28254.1 - 1.4e-06 28.0 0.0 2.2e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 KFM28254.1 - 0.031 14.9 0.2 0.072 13.7 0.1 1.7 1 1 0 1 1 1 0 Helix-hairpin-helix domain UNC-50 PF05216.13 KFM28256.1 - 4.1e-59 199.8 5.1 4.7e-59 199.6 5.1 1.0 1 0 0 1 1 1 1 UNC-50 family DUF4538 PF15061.6 KFM28256.1 - 5 6.9 4.9 1.5 8.6 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) eIF-5_eIF-2B PF01873.17 KFM28257.1 - 8.6e-38 128.8 0.1 1.4e-37 128.2 0.1 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 KFM28257.1 - 7.4e-16 58.1 0.1 2.5e-15 56.4 0.1 1.9 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Glyco_hydro_3_C PF01915.22 KFM28257.1 - 0.0013 18.7 0.3 0.0017 18.4 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain NAD_binding_9 PF13454.6 KFM28257.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Zn_Tnp_IS1595 PF12760.7 KFM28257.1 - 0.14 12.2 0.3 0.43 10.6 0.3 1.9 1 0 0 1 1 1 0 Transposase zinc-ribbon domain CCDC53 PF10152.9 KFM28257.1 - 1.8 8.9 7.3 16 5.9 7.3 2.1 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex CPSF100_C PF13299.6 KFM28257.1 - 1.9 8.6 7.0 4.7 7.4 7.0 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF2057 PF09829.9 KFM28257.1 - 2.3 8.4 7.8 1.8 8.7 5.9 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) Dsh_C PF12316.8 KFM28257.1 - 3.6 7.9 7.6 5.8 7.3 7.6 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Peptidase_S8 PF00082.22 KFM28258.1 - 4.7e-31 108.1 0.0 3.1e-30 105.5 0.0 2.3 1 1 0 1 1 1 1 Subtilase family PA PF02225.22 KFM28258.1 - 3.3e-09 36.6 0.6 3.3e-09 36.6 0.6 2.6 2 0 0 2 2 2 1 PA domain Y_Y_Y PF07495.13 KFM28258.1 - 3.1e-06 27.1 0.0 3.1 7.8 0.0 4.6 5 0 0 5 5 5 3 Y_Y_Y domain Big_3_3 PF13750.6 KFM28258.1 - 3.8e-06 26.7 0.6 6.1 6.5 0.0 5.4 6 0 0 6 6 6 3 Bacterial Ig-like domain (group 3) Big_3_2 PF12245.8 KFM28258.1 - 0.043 14.1 0.3 0.49 10.7 0.0 3.0 4 0 0 4 4 4 0 Bacterial Ig-like domain UIM PF02809.20 KFM28258.1 - 0.16 11.9 14.6 0.68 10.0 4.6 2.6 2 0 0 2 2 2 0 Ubiquitin interaction motif RAP80_UIM PF18282.1 KFM28258.1 - 0.5 10.2 7.3 2.3 8.0 0.0 2.8 3 0 0 3 3 3 0 RAP80 N-terminal ubiquitin interaction motif S1 PF00575.23 KFM28261.1 - 6.7e-52 173.7 8.4 8.7e-12 45.2 0.0 12.0 13 1 0 13 13 13 7 S1 RNA binding domain RNase_II_C_S1 PF18614.1 KFM28261.1 - 2.1e-05 24.4 18.4 0.56 10.2 0.8 8.8 7 1 1 8 8 8 2 RNase II-type exonuclease C-terminal S1 domain D-ser_dehydrat PF14031.6 KFM28261.1 - 0.095 13.4 3.8 24 5.7 0.1 4.2 4 0 0 4 4 4 0 Putative serine dehydratase domain Peptidase_M60_C PF18630.1 KFM28261.1 - 6 7.1 7.4 25 5.1 0.9 2.5 2 0 0 2 2 2 0 Peptidase M60 C-terminal domain PIP5K PF01504.18 KFM28262.1 - 1.6e-68 230.9 0.0 5.5e-68 229.2 0.0 1.8 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase MORN PF02493.20 KFM28262.1 - 4.1e-05 23.2 5.0 0.048 13.6 0.3 3.5 3 0 0 3 3 3 2 MORN repeat zf-CCCH PF00642.24 KFM28265.1 - 1.1e-13 50.7 14.6 1.8e-07 30.9 3.0 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KFM28265.1 - 1e-06 29.4 2.1 0.035 14.8 0.3 2.2 2 0 0 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 KFM28265.1 - 1.1e-05 25.4 15.3 0.005 16.9 2.3 2.5 2 0 0 2 2 2 2 Zinc finger domain RRM_1 PF00076.22 KFM28265.1 - 1.4e-05 24.8 0.3 6.1e-05 22.8 0.1 2.0 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_3 PF15663.5 KFM28265.1 - 0.00088 19.5 0.6 0.92 9.8 0.1 2.3 2 0 0 2 2 2 2 Zinc-finger containing family Nup35_RRM_2 PF14605.6 KFM28265.1 - 0.19 11.8 0.4 1 9.4 0.0 2.3 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif zf-CCCH_4 PF18044.1 KFM28265.1 - 4.8 7.1 16.9 0.19 11.5 3.5 2.6 3 0 0 3 3 3 0 CCCH-type zinc finger UCR_UQCRX_QCR9 PF05365.12 KFM28266.1 - 5.4e-15 55.1 0.3 6.3e-15 54.9 0.3 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like EB1 PF03271.17 KFM28268.1 - 4.6e-16 58.8 0.0 8.8e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif Seadorna_VP6 PF07407.11 KFM28268.1 - 0.00043 19.4 0.3 0.00043 19.4 0.3 1.5 2 0 0 2 2 2 1 Seadornavirus VP6 protein Mto2_bdg PF12808.7 KFM28268.1 - 0.029 14.7 0.8 0.052 13.9 0.8 1.5 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region bZIP_1 PF00170.21 KFM28268.1 - 0.03 14.4 0.1 0.062 13.4 0.1 1.5 1 0 0 1 1 1 0 bZIP transcription factor APG6_N PF17675.1 KFM28268.1 - 0.03 14.8 0.7 0.052 14.1 0.7 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Leu_zip PF15294.6 KFM28268.1 - 0.03 13.8 0.2 0.045 13.3 0.2 1.2 1 0 0 1 1 1 0 Leucine zipper GIT_CC PF16559.5 KFM28268.1 - 0.035 14.0 0.1 0.068 13.1 0.1 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor TSC22 PF01166.18 KFM28268.1 - 0.039 14.3 0.2 0.074 13.4 0.2 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family ZapB PF06005.12 KFM28268.1 - 0.045 14.2 0.1 0.098 13.1 0.1 1.5 1 0 0 1 1 1 0 Cell division protein ZapB CCDC106 PF15794.5 KFM28268.1 - 0.048 13.4 0.2 10 5.7 0.1 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 CENP-F_leu_zip PF10473.9 KFM28268.1 - 0.055 13.5 0.4 0.055 13.5 0.4 1.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cep57_CLD_2 PF14197.6 KFM28268.1 - 0.061 13.4 3.6 0.067 13.3 2.1 1.9 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 HALZ PF02183.18 KFM28268.1 - 0.078 13.2 1.3 0.078 13.2 1.3 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper GAS PF13851.6 KFM28268.1 - 0.081 12.3 0.5 0.14 11.5 0.5 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Mito_carr PF00153.27 KFM28269.1 - 2.7e-50 168.2 4.0 3.9e-15 55.5 0.0 4.1 2 2 2 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 KFM28269.1 - 0.00028 20.1 0.3 0.39 9.8 0.0 3.2 3 0 0 3 3 3 3 Gammaproteobacterial serine protease DUF5054 PF16477.5 KFM28270.1 - 2.1e-29 103.2 0.0 8.7e-18 65.1 0.0 2.7 2 1 0 2 2 2 2 Domain of unknown function (DUF5054) BAG6 PF12057.8 KFM28270.1 - 0.21 11.3 0.0 0.36 10.5 0.0 1.3 1 0 0 1 1 1 0 BCL2-associated athanogene 6 Ribosomal_L18A PF01775.17 KFM28272.1 - 3.7e-52 175.5 1.3 4.9e-52 175.1 1.3 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A UCH PF00443.29 KFM28273.1 - 3.7e-54 183.9 0.0 4.5e-54 183.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFM28273.1 - 6.1e-23 81.9 1.7 7.4e-21 75.1 1.7 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase HscB_4_cys PF18256.1 KFM28273.1 - 0.047 13.5 0.1 0.12 12.2 0.1 1.7 1 0 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif SBP PF03110.14 KFM28273.1 - 0.057 13.7 1.1 0.11 12.8 1.1 1.4 1 0 0 1 1 1 0 SBP domain ANAPC16 PF17256.2 KFM28273.1 - 0.15 12.5 0.2 1.9 8.9 0.2 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex, subunit 16 Peptidase_C98 PF15499.6 KFM28273.1 - 0.24 10.9 2.7 2.8 7.3 0.5 2.7 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Glutaredoxin PF00462.24 KFM28274.1 - 1.8e-16 60.1 0.0 3e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 KFM28274.1 - 0.0055 17.1 0.0 0.014 15.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GILT PF03227.16 KFM28275.1 - 1.2e-19 70.5 0.4 2e-18 66.6 0.9 2.0 2 0 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Thioredoxin_4 PF13462.6 KFM28275.1 - 0.00092 19.4 0.0 0.0013 18.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DnaJ-X PF14308.6 KFM28276.1 - 2.3e-26 92.6 0.0 1.9e-15 56.9 0.0 2.2 1 1 1 2 2 2 2 X-domain of DnaJ-containing DnaJ PF00226.31 KFM28276.1 - 3.4e-21 75.1 0.0 5.9e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain ATG_C PF09333.11 KFM28276.1 - 5.2e-07 29.9 0.4 1.4e-06 28.6 0.4 1.7 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Antimicrobial_2 PF08023.12 KFM28276.1 - 4.8 7.8 7.5 5 7.8 1.8 2.6 2 0 0 2 2 2 0 Frog antimicrobial peptide TPT PF03151.16 KFM28278.1 - 1.8e-25 89.9 23.1 2.2e-25 89.6 23.1 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KFM28278.1 - 2.6e-08 33.4 23.3 3.3e-08 33.1 23.3 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KFM28278.1 - 0.00059 20.0 15.0 0.00059 20.0 15.0 2.2 2 0 0 2 2 2 1 EamA-like transporter family Scramblase PF03803.15 KFM28279.1 - 3.4e-49 167.1 0.0 4.3e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 Scramblase Aldo_ket_red PF00248.21 KFM28280.1 - 1.7e-53 181.8 0.0 1.8e-53 181.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Abhydrolase_1 PF00561.20 KFM28281.1 - 5.7e-10 39.3 0.1 1.1e-09 38.3 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFM28281.1 - 5.6e-07 29.1 0.0 1.1e-06 28.1 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFM28281.1 - 2.7e-05 24.9 2.3 2.7e-05 24.9 2.3 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family zf-RING_2 PF13639.6 KFM28282.1 - 1.8e-06 28.2 1.2 4.3e-06 27.0 1.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KFM28282.1 - 2.1e-06 27.9 0.6 3.8e-06 27.1 0.6 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KFM28282.1 - 5e-06 26.3 0.1 8.5e-06 25.5 0.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM28282.1 - 5.5e-05 23.0 0.4 0.0001 22.1 0.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFM28282.1 - 9.3e-05 22.2 1.2 0.00018 21.3 1.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFM28282.1 - 0.00014 21.6 0.3 0.00024 20.9 0.3 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KFM28282.1 - 0.00016 21.2 0.9 0.00031 20.3 0.9 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 KFM28282.1 - 0.00022 20.9 0.0 0.00048 19.8 0.0 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 KFM28282.1 - 0.0019 18.2 0.5 0.0043 17.1 0.5 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KFM28282.1 - 0.0096 15.8 0.6 0.016 15.0 0.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFM28282.1 - 0.014 15.4 2.2 0.032 14.2 2.2 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3H2C3 PF17122.5 KFM28282.1 - 0.049 13.7 6.1 0.19 11.8 6.1 2.0 1 1 0 1 1 1 0 Zinc-finger Glyco_transf_20 PF00982.21 KFM28283.1 - 1.7e-148 495.2 0.0 2.2e-148 494.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KFM28283.1 - 1.2e-72 243.8 0.0 1.7e-72 243.3 0.0 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 KFM28283.1 - 0.022 14.5 0.0 0.28 10.9 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KFM28284.1 - 3.7e-51 174.3 0.0 4.2e-51 174.1 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 KFM28284.1 - 6e-16 58.7 0.0 1.5e-10 41.1 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 KFM28284.1 - 2e-07 31.5 1.8 0.0019 18.5 0.0 3.3 2 2 2 4 4 4 3 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFM28284.1 - 2.8e-05 24.6 2.4 0.68 10.3 0.0 3.5 1 1 3 4 4 4 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KFM28284.1 - 0.00053 20.1 0.0 0.0013 18.8 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KFM28284.1 - 0.025 14.7 0.0 6 6.9 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.16 KFM28284.1 - 0.065 12.4 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Trehalose-phosphatase Methyltransf_21 PF05050.12 KFM28285.1 - 6e-11 42.7 0.0 9.9e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain OrfB_Zn_ribbon PF07282.11 KFM28286.1 - 0.00035 20.4 6.4 0.0017 18.2 6.4 1.9 1 1 0 1 1 1 1 Putative transposase DNA-binding domain OTT_1508_deam PF14441.6 KFM28286.1 - 0.012 15.6 0.7 0.024 14.6 0.7 1.5 1 0 0 1 1 1 0 OTT_1508-like deaminase Xpo1 PF08389.12 KFM28287.1 - 0.074 13.1 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 Exportin 1-like protein CorA PF01544.18 KFM28288.1 - 0.00017 21.1 0.1 0.00026 20.4 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.12 KFM28288.1 - 0.061 13.4 0.8 0.12 12.4 0.8 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus 4HBT PF03061.22 KFM28289.1 - 0.006 16.9 0.2 0.97 9.8 0.1 2.4 2 0 0 2 2 2 2 Thioesterase superfamily PAP2 PF01569.21 KFM28290.1 - 2.5e-24 85.6 5.4 3.3e-24 85.2 2.8 2.1 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 KFM28290.1 - 0.012 15.4 0.7 0.012 15.4 0.7 3.3 3 1 1 4 4 4 0 PAP2 superfamily COX4_pro_2 PF07835.12 KFM28290.1 - 0.75 9.9 3.2 0.45 10.7 0.4 2.2 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV DUF563 PF04577.14 KFM28291.1 - 5e-39 134.6 1.4 7e-13 49.2 0.0 4.1 2 1 2 4 4 4 3 Protein of unknown function (DUF563) SBP PF03110.14 KFM28292.1 - 2.8e-25 88.4 12.5 3.9e-25 88.0 12.5 1.2 1 0 0 1 1 1 1 SBP domain Vps36-NZF-N PF16988.5 KFM28292.1 - 0.026 13.9 0.1 0.049 13.0 0.1 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain PAP_fibrillin PF04755.12 KFM28294.1 - 2.9e-18 66.5 0.0 2.4e-14 53.7 0.0 2.5 2 1 0 2 2 2 2 PAP_fibrillin Mobilization_B PF17511.2 KFM28294.1 - 0.66 10.4 7.4 1.4 9.2 7.4 1.6 1 0 0 1 1 1 0 Mobilization protein B DUF1754 PF08555.10 KFM28297.1 - 8.7e-06 26.4 10.5 1.3e-05 25.9 10.5 1.2 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) Peptidase_S8 PF00082.22 KFM28298.1 - 7.7e-12 45.1 2.1 1.1e-11 44.6 2.1 1.2 1 0 0 1 1 1 1 Subtilase family Acetyltransf_1 PF00583.25 KFM28299.1 - 8.1e-10 39.0 0.1 1.1e-09 38.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFM28299.1 - 1.2e-08 34.9 0.0 1.6e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFM28299.1 - 1.1e-06 29.0 0.0 1.4e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFM28299.1 - 2.7e-05 24.0 0.0 4.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KFM28299.1 - 0.013 15.5 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pkinase PF00069.25 KFM28300.1 - 2.2e-60 204.2 0.0 3.3e-60 203.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM28300.1 - 3.5e-22 78.9 0.0 1.5e-21 76.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFM28300.1 - 0.003 16.6 0.0 0.0046 16.0 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KFM28300.1 - 0.065 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Hydrolase_like PF13242.6 KFM28301.1 - 3e-18 65.7 0.8 5.4e-18 64.8 0.8 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 KFM28301.1 - 7.1e-16 58.2 0.0 1.5e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KFM28301.1 - 1.2e-09 38.5 0.0 4e-07 30.3 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFM28301.1 - 4.6e-08 33.6 0.8 7.1e-06 26.5 0.1 2.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase G6PD_C PF02781.16 KFM28302.1 - 5.1e-108 360.7 0.0 6.3e-108 360.4 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KFM28302.1 - 3.9e-54 184.0 0.0 5.5e-54 183.5 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Acetyltransf_10 PF13673.7 KFM28303.1 - 3.9e-08 33.3 0.2 1.2e-07 31.7 0.4 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFM28303.1 - 8.2e-06 26.2 0.1 2.4e-05 24.7 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFM28303.1 - 3.8e-05 23.9 0.2 0.00011 22.4 0.3 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KFM28303.1 - 0.0049 16.8 0.1 0.012 15.6 0.1 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KFM28303.1 - 0.059 13.5 0.4 0.2 11.8 0.2 1.9 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase E2F_TDP PF02319.20 KFM28304.1 - 2.1e-38 130.2 0.0 2.9e-18 65.7 0.0 2.2 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.19 KFM28304.1 - 0.0077 16.1 0.1 0.015 15.2 0.1 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB B-block_TFIIIC PF04182.12 KFM28304.1 - 0.14 12.4 0.0 8.5 6.6 0.0 2.3 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC MMR_HSR1_Xtn PF16897.5 KFM28305.1 - 2.5e-39 133.6 0.1 4.2e-39 132.8 0.1 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KFM28305.1 - 1.9e-21 76.3 0.0 3.9e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 KFM28305.1 - 1.1e-20 73.4 0.0 1.9e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 KFM28305.1 - 4.1e-11 42.6 0.1 1.1e-10 41.3 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KFM28305.1 - 6.4e-05 23.1 0.2 0.33 11.0 0.2 2.5 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 KFM28305.1 - 0.0034 16.4 0.9 0.0049 15.9 0.1 1.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 KFM28305.1 - 0.015 14.9 0.5 10 5.6 0.0 3.9 2 2 1 3 3 3 0 Elongation factor Tu GTP binding domain AIG1 PF04548.16 KFM28305.1 - 0.015 14.6 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 AIG1 family RsgA_GTPase PF03193.16 KFM28305.1 - 0.064 13.1 0.1 0.62 10.0 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase SF3A2 PF16835.5 KFM28306.1 - 4.6e-23 81.4 0.1 6e-23 81.0 0.1 1.2 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) NFACT-R_1 PF05670.13 KFM28307.1 - 3.2e-42 143.6 0.0 8.2e-42 142.3 0.0 1.6 2 0 0 2 2 2 1 NFACT protein RNA binding domain DUF4025 PF13217.6 KFM28307.1 - 0.096 12.6 1.8 0.19 11.6 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4025) FUSC PF04632.12 KFM28307.1 - 0.62 8.5 1.6 0.8 8.2 1.6 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Aminotran_5 PF00266.19 KFM28308.1 - 5.7e-122 407.2 0.0 1.7e-121 405.7 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KFM28308.1 - 3.9e-08 32.9 0.0 5.3e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KFM28308.1 - 1.8e-06 27.5 0.4 7.3e-06 25.5 1.3 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KFM28308.1 - 0.00013 20.6 0.0 0.0015 17.1 0.0 2.0 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme CAP_N PF01213.19 KFM28309.1 - 0.7 9.3 2.1 0.74 9.2 2.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal TPR_1 PF00515.28 KFM28310.1 - 5.9e-10 38.5 12.2 2.1e-06 27.3 0.5 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFM28310.1 - 1.6e-08 34.0 11.8 0.00065 19.6 0.2 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFM28310.1 - 5.4e-06 26.5 7.3 1.8e-05 24.8 5.2 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat FKBP_C PF00254.28 KFM28310.1 - 2.9e-05 24.3 0.0 4.5 7.7 0.0 4.1 3 1 0 3 3 3 2 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_8 PF13181.6 KFM28310.1 - 3.5e-05 23.7 7.6 0.0015 18.6 0.1 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFM28310.1 - 0.00039 20.7 9.0 0.015 15.6 6.4 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFM28310.1 - 0.00046 20.8 10.1 0.008 16.8 8.9 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFM28310.1 - 0.043 14.2 1.2 0.25 11.8 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFM28310.1 - 0.047 13.8 2.8 0.98 9.5 0.7 3.3 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.6 KFM28310.1 - 0.14 11.9 6.2 7.5 6.3 0.1 4.0 3 1 1 4 4 4 0 TPR repeat TPR_MalT PF17874.1 KFM28310.1 - 0.14 11.5 7.1 0.046 13.1 3.6 1.8 2 0 0 2 2 2 0 MalT-like TPR region TPR_10 PF13374.6 KFM28310.1 - 0.15 12.0 4.0 10 6.1 0.4 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat CusF_Ec PF11604.8 KFM28310.1 - 0.17 11.9 0.2 1.5 8.9 0.0 2.4 2 1 1 3 3 3 0 Copper binding periplasmic protein CusF TPR_7 PF13176.6 KFM28310.1 - 1.9 8.7 6.0 0.29 11.3 0.2 2.7 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFM28310.1 - 1.9 9.1 11.2 0.23 12.0 5.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFM28310.1 - 2.5 9.2 6.8 2.9 9.0 0.9 3.1 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFM28310.1 - 4.6 8.1 6.7 38 5.2 0.8 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat SOUL PF04832.12 KFM28311.1 - 3.8e-23 82.5 0.0 5e-23 82.1 0.0 1.0 1 0 0 1 1 1 1 SOUL heme-binding protein DUF4996 PF16387.5 KFM28311.1 - 0.059 13.9 0.0 0.084 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function KH_2 PF07650.17 KFM28312.1 - 1.8e-08 34.1 0.1 2.5e-08 33.6 0.1 1.2 1 0 0 1 1 1 1 KH domain MMR_HSR1 PF01926.23 KFM28313.1 - 8.9e-16 58.0 0.2 1.3e-15 57.5 0.2 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFM28313.1 - 5.9e-06 25.9 0.2 7.7e-06 25.5 0.2 1.1 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KFM28313.1 - 8.1e-06 26.0 1.5 0.00035 20.7 0.3 2.1 1 1 1 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 KFM28313.1 - 0.00015 21.7 0.1 0.00018 21.5 0.1 1.1 1 0 0 1 1 1 1 RsgA GTPase AIG1 PF04548.16 KFM28313.1 - 0.00066 19.1 0.1 0.00086 18.7 0.1 1.1 1 0 0 1 1 1 1 AIG1 family MeaB PF03308.16 KFM28313.1 - 0.013 14.5 0.1 0.015 14.3 0.1 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 KFM28313.1 - 0.029 13.9 0.1 0.051 13.1 0.0 1.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Arf PF00025.21 KFM28313.1 - 0.047 13.2 0.0 0.055 12.9 0.0 1.1 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_18 PF13238.6 KFM28313.1 - 0.091 13.3 0.1 0.11 13.0 0.1 1.2 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFM28313.1 - 0.1 13.1 0.0 0.13 12.8 0.0 1.2 1 0 0 1 1 1 0 ABC transporter RRM_1 PF00076.22 KFM28314.1 - 1.3e-34 117.8 0.0 5.5e-20 71.0 0.0 4.5 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFM28314.1 - 2.4e-08 34.0 0.1 0.00015 21.8 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 KFM28314.1 - 0.0016 18.2 0.0 2.4 8.1 0.0 3.1 2 1 1 3 3 3 2 Occluded RNA-recognition motif PHM7_cyt PF14703.6 KFM28314.1 - 0.018 15.3 0.0 0.13 12.5 0.0 2.3 3 0 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter HalX PF08663.10 KFM28314.1 - 0.19 12.1 0.3 0.4 11.0 0.3 1.4 1 0 0 1 1 1 0 HalX domain Chorein_N PF12624.7 KFM28316.1 - 1.4e-14 54.2 0.1 2.3e-14 53.5 0.1 1.3 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 IFRD PF05004.13 KFM28318.1 - 5.6e-50 170.2 0.0 3.1e-49 167.7 0.0 1.9 1 1 0 1 1 1 1 Interferon-related developmental regulator (IFRD) IFRD_C PF04836.12 KFM28318.1 - 1.2e-05 25.8 0.8 2.9e-05 24.6 0.8 1.6 1 0 0 1 1 1 1 Interferon-related protein conserved region TRAP_alpha PF03896.16 KFM28319.1 - 0.00039 19.7 0.0 0.0033 16.7 0.0 1.9 2 0 0 2 2 2 1 Translocon-associated protein (TRAP), alpha subunit ArsA_ATPase PF02374.15 KFM28320.1 - 2.1e-129 431.1 0.0 1.8e-66 224.4 0.0 2.1 2 0 0 2 2 2 2 Anion-transporting ATPase CbiA PF01656.23 KFM28320.1 - 2.3e-21 76.2 0.0 2.9e-09 37.1 0.0 2.4 2 1 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KFM28320.1 - 5.1e-15 55.8 0.1 4.5e-06 26.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain ParA PF10609.9 KFM28320.1 - 1.7e-13 50.6 8.6 2.4e-05 23.9 0.2 4.8 5 0 0 5 5 5 2 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 KFM28320.1 - 1.8e-08 34.3 0.5 0.0014 18.3 0.1 2.4 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain CBP_BcsQ PF06564.12 KFM28320.1 - 6.2e-08 32.4 0.2 0.011 15.3 0.0 2.3 2 0 0 2 2 2 2 Cellulose biosynthesis protein BcsQ AAA_16 PF13191.6 KFM28320.1 - 1e-07 32.5 1.6 6.6e-05 23.4 0.4 2.9 2 1 0 2 2 2 1 AAA ATPase domain Fer4_NifH PF00142.18 KFM28320.1 - 1.8e-07 30.9 0.1 0.018 14.5 0.0 2.5 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family IstB_IS21 PF01695.17 KFM28320.1 - 1.6e-05 24.8 0.3 0.025 14.3 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_24 PF13479.6 KFM28320.1 - 2.5e-05 24.1 0.0 0.076 12.7 0.0 2.9 2 2 0 2 2 2 2 AAA domain PhoH PF02562.16 KFM28320.1 - 3.7e-05 23.3 0.2 0.035 13.6 0.1 2.5 2 0 0 2 2 2 2 PhoH-like protein MeaB PF03308.16 KFM28320.1 - 4.3e-05 22.6 1.6 0.016 14.2 0.2 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB ResIII PF04851.15 KFM28320.1 - 0.0005 20.1 0.0 1.1 9.2 0.0 3.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_25 PF13481.6 KFM28320.1 - 0.00054 19.6 6.7 0.05 13.2 0.2 2.8 3 0 0 3 3 2 2 AAA domain NACHT PF05729.12 KFM28320.1 - 0.0007 19.6 1.0 0.076 12.9 0.0 2.7 2 0 0 2 2 2 1 NACHT domain ATP_bind_1 PF03029.17 KFM28320.1 - 0.0012 18.7 1.3 0.21 11.4 0.1 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 KFM28320.1 - 0.0012 18.6 0.1 1.4 8.7 0.0 2.5 2 0 0 2 2 2 2 mRNA cleavage and polyadenylation factor CLP1 P-loop NB-ARC PF00931.22 KFM28320.1 - 0.0018 17.5 0.4 0.082 12.1 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain DUF3763 PF12592.8 KFM28320.1 - 0.0024 17.9 0.1 0.22 11.6 0.0 2.8 3 0 0 3 3 2 1 Protein of unknown function (DUF3763) LpxK PF02606.14 KFM28320.1 - 0.0034 16.5 0.8 1.9 7.5 0.0 2.5 2 0 0 2 2 2 2 Tetraacyldisaccharide-1-P 4'-kinase ATPase PF06745.13 KFM28320.1 - 0.0037 16.7 1.7 0.16 11.3 0.1 2.7 3 0 0 3 3 2 1 KaiC RNA_helicase PF00910.22 KFM28320.1 - 0.0044 17.4 0.0 1.3 9.4 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_7 PF12775.7 KFM28320.1 - 0.0095 15.5 0.1 1.3 8.5 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 KFM28320.1 - 0.011 15.9 2.3 8.4 6.5 1.0 3.6 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KFM28320.1 - 0.012 15.5 0.3 1 9.2 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase DnaB_C PF03796.15 KFM28320.1 - 0.013 14.9 0.5 0.9 8.8 0.1 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_22 PF13401.6 KFM28320.1 - 0.013 15.8 0.2 1.9 8.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KFM28320.1 - 0.013 15.2 5.0 1.4 8.6 0.3 3.6 4 0 0 4 4 4 0 AAA domain Zeta_toxin PF06414.12 KFM28320.1 - 0.021 14.1 0.7 3.1 7.0 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.29 KFM28320.1 - 0.034 14.6 0.4 3.4 8.1 0.0 2.8 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 KFM28320.1 - 0.067 13.4 0.1 2.4 8.4 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 KFM28320.1 - 0.072 13.6 0.5 2.4 8.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KFM28320.1 - 0.073 12.2 0.0 5.2 6.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) KTI12 PF08433.10 KFM28320.1 - 0.092 12.2 0.1 2.4 7.5 0.0 2.3 2 0 0 2 2 2 0 Chromatin associated protein KTI12 TsaE PF02367.17 KFM28320.1 - 0.093 12.7 0.4 4.7 7.2 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE APS_kinase PF01583.20 KFM28320.1 - 0.18 11.7 0.3 13 5.6 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase PIF1 PF05970.14 KFM28320.1 - 0.19 10.9 0.3 9.8 5.2 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase Acyltransferase PF01553.21 KFM28321.1 - 7.2e-06 25.7 0.0 1.4e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase zf-Tim10_DDP PF02953.15 KFM28323.1 - 1.4e-18 66.3 0.2 1.6e-18 66.1 0.2 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger FGGY_C PF02782.16 KFM28324.1 - 3.9e-26 92.0 0.3 1.2e-19 70.8 0.0 2.3 1 1 1 2 2 2 2 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KFM28324.1 - 1.3e-21 77.3 0.0 1.9e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain zf-RING_9 PF13901.6 KFM28325.1 - 0.42 10.5 0.0 0.42 10.5 0.0 1.8 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon DnaJ_CXXCXGXG PF00684.19 KFM28325.1 - 3.6 8.0 15.9 20 5.7 16.1 2.0 1 1 0 1 1 1 0 DnaJ central domain zf-RING_9 PF13901.6 KFM28326.1 - 0.42 10.5 0.0 0.42 10.5 0.0 1.8 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon DnaJ_CXXCXGXG PF00684.19 KFM28326.1 - 3.6 8.0 15.9 20 5.7 16.1 2.0 1 1 0 1 1 1 0 DnaJ central domain DUF2358 PF10184.9 KFM28327.1 - 5.2e-28 97.6 0.0 8.8e-28 96.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) Surp PF01805.20 KFM28327.1 - 6.5e-17 61.3 0.0 1.2e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 Surp module RRM_1 PF00076.22 KFM28327.1 - 6.5e-11 41.9 0.0 2.8e-10 39.9 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFM28327.1 - 0.017 15.3 0.0 0.03 14.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif CTD_bind PF04818.13 KFM28327.1 - 0.039 14.8 0.0 0.12 13.2 0.0 1.9 2 0 0 2 2 2 0 RNA polymerase II-binding domain. TMEM151 PF14857.6 KFM28327.1 - 0.26 10.2 0.0 0.48 9.3 0.0 1.3 1 0 0 1 1 1 0 TMEM151 family Cullin_binding PF03556.15 KFM28328.1 - 7.5e-34 116.7 0.5 1.2e-33 116.1 0.5 1.4 1 0 0 1 1 1 1 Cullin binding COX17 PF05051.13 KFM28328.1 - 1.9e-20 72.9 4.6 5e-20 71.6 4.6 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) UBA_4 PF14555.6 KFM28328.1 - 1.5e-10 40.8 0.0 3.3e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain TPR_1 PF00515.28 KFM28329.1 - 8.1e-31 104.6 3.7 4.4e-05 23.1 0.0 7.6 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.17 KFM28329.1 - 4.6e-26 88.8 26.8 0.0013 18.7 0.0 9.5 11 0 0 11 11 10 7 Tetratricopeptide repeat ANAPC3 PF12895.7 KFM28329.1 - 9e-18 64.3 13.2 5.2e-11 42.6 0.3 4.9 3 1 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KFM28329.1 - 1e-17 62.8 0.1 0.0021 18.1 0.0 6.8 7 0 0 7 7 7 4 Tetratricopeptide repeat Cyt_b-c1_8 PF10890.8 KFM28329.1 - 4.3e-16 59.1 0.0 9.1e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b-c1 complex subunit 8 TPR_14 PF13428.6 KFM28329.1 - 7.3e-16 57.5 37.8 0.0038 17.9 1.9 9.6 3 1 7 10 10 10 6 Tetratricopeptide repeat TPR_11 PF13414.6 KFM28329.1 - 8.6e-15 54.1 0.0 0.00044 19.9 0.1 6.3 4 3 4 8 8 8 3 TPR repeat TPR_16 PF13432.6 KFM28329.1 - 9.3e-15 55.0 39.1 4.7e-06 27.2 0.1 7.2 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFM28329.1 - 3.2e-14 51.8 5.8 0.024 14.6 0.2 6.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 KFM28329.1 - 4.3e-13 49.6 22.5 0.00013 22.4 2.1 6.9 5 2 2 8 8 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 KFM28329.1 - 2.2e-10 40.7 30.9 0.023 15.0 1.6 7.9 5 1 4 9 9 8 6 Tetratricopeptide repeat TPR_17 PF13431.6 KFM28329.1 - 4.6e-10 39.2 8.3 0.031 14.6 0.0 7.3 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 KFM28329.1 - 3.7e-05 23.1 7.3 0.081 12.1 0.6 4.3 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 KFM28329.1 - 0.00037 20.6 27.6 0.004 17.3 0.6 5.6 2 1 5 7 7 7 4 Tetratricopeptide repeat TPR_20 PF14561.6 KFM28329.1 - 0.00098 19.4 1.2 0.0094 16.3 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFM28329.1 - 0.0038 17.8 14.5 10 7.0 0.0 7.1 8 0 0 8 8 6 0 Tetratricopeptide repeat UcrQ PF02939.16 KFM28329.1 - 0.039 13.9 0.0 0.081 12.9 0.0 1.5 1 0 0 1 1 1 0 UcrQ family Fis1_TPR_C PF14853.6 KFM28329.1 - 0.46 10.6 5.4 1.1e+02 3.0 0.0 4.8 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 KFM28329.1 - 1.2 9.1 21.3 2.1 8.3 1.9 6.9 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_21 PF09976.9 KFM28329.1 - 1.7 8.3 4.3 0.48 10.1 0.1 2.1 3 0 0 3 3 2 0 Tetratricopeptide repeat-like domain ThiF PF00899.21 KFM28330.1 - 8e-19 68.0 0.0 1.9e-18 66.7 0.0 1.6 1 1 0 1 1 1 1 ThiF family Cellulase PF00150.18 KFM28332.1 - 1.8e-10 40.7 1.9 4.3e-10 39.5 1.9 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PfkB PF00294.24 KFM28333.1 - 6.7e-09 35.5 1.2 1.1e-08 34.8 0.3 1.7 2 0 0 2 2 2 1 pfkB family carbohydrate kinase Engrail_1_C_sig PF10525.9 KFM28333.1 - 0.17 11.1 2.2 0.37 10.1 2.2 1.5 1 0 0 1 1 1 0 Engrailed homeobox C-terminal signature domain GST_C_6 PF17171.4 KFM28335.1 - 0.6 9.9 2.8 0.63 9.9 0.1 2.4 2 2 2 4 4 4 0 Glutathione S-transferase, C-terminal domain Apolipoprotein PF01442.18 KFM28336.1 - 4.2e-05 23.5 4.3 5.2e-05 23.2 4.3 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain YtxH PF12732.7 KFM28336.1 - 0.0001 22.7 21.2 0.0012 19.3 9.3 2.1 1 1 1 2 2 2 2 YtxH-like protein Oleosin PF01277.17 KFM28336.1 - 0.00012 21.8 5.0 0.0052 16.5 0.1 2.1 2 0 0 2 2 2 2 Oleosin ATP-synt_B PF00430.18 KFM28336.1 - 0.018 15.2 15.2 0.026 14.6 15.2 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Entericidin PF08085.11 KFM28336.1 - 0.034 14.2 3.3 5.1 7.3 0.6 2.8 2 0 0 2 2 2 0 Entericidin EcnA/B family ApoLp-III PF07464.11 KFM28336.1 - 0.036 14.2 9.2 0.055 13.6 9.2 1.4 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Mitofilin PF09731.9 KFM28336.1 - 0.039 12.8 14.8 0.038 12.9 14.8 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF883 PF05957.13 KFM28336.1 - 0.073 13.7 16.0 0.068 13.8 11.8 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF4228 PF14009.6 KFM28336.1 - 0.096 13.1 2.3 0.11 12.9 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) CheX PF13690.6 KFM28336.1 - 0.11 12.7 0.3 0.16 12.2 0.3 1.4 1 1 0 1 1 1 0 Chemotaxis phosphatase CheX CLN3 PF02487.17 KFM28336.1 - 0.14 11.2 0.5 0.17 10.9 0.5 1.0 1 0 0 1 1 1 0 CLN3 protein PIN_8 PF18476.1 KFM28336.1 - 0.23 11.3 7.1 0.26 11.1 7.1 1.1 1 0 0 1 1 1 0 PIN like domain V-ATPase_G_2 PF16999.5 KFM28336.1 - 0.49 10.8 13.1 0.72 10.3 13.1 1.4 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit RRF PF01765.19 KFM28336.1 - 0.51 10.3 12.9 0.63 10.0 12.9 1.2 1 0 0 1 1 1 0 Ribosome recycling factor DUF1542 PF07564.11 KFM28336.1 - 0.59 10.3 22.7 5.3 7.2 22.3 2.4 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1542) Phasin PF05597.11 KFM28336.1 - 0.64 10.0 11.1 2.5 8.1 4.1 2.1 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DivIVA PF05103.13 KFM28336.1 - 1.1 9.4 14.1 1.9 8.6 14.1 1.6 1 1 0 1 1 1 0 DivIVA protein Alanine_zipper PF11839.8 KFM28336.1 - 1.2 9.6 30.1 43 4.6 30.1 2.5 1 1 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein Phe_tRNA-synt_N PF02912.18 KFM28336.1 - 1.9 8.5 11.6 4.1 7.4 1.3 2.4 1 1 1 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain Chlorosome_CsmC PF11098.8 KFM28336.1 - 2.3 8.2 11.3 2.1 8.3 9.0 1.9 1 1 1 2 2 2 0 Chlorosome envelope protein C Presenilin PF01080.17 KFM28336.1 - 8.2 5.1 5.4 8.5 5.0 5.4 1.0 1 0 0 1 1 1 0 Presenilin PTS_IIA PF02255.16 KFM28336.1 - 8.7 6.5 15.1 72 3.5 11.8 2.7 1 1 1 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit eIF2_C PF09173.11 KFM28338.1 - 7.6e-37 125.4 0.4 1.9e-36 124.2 0.4 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 KFM28338.1 - 4.6e-24 85.0 0.3 4.8e-23 81.7 0.3 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KFM28338.1 - 1.4e-10 41.4 2.1 1.4e-10 41.4 0.4 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 KFM28338.1 - 0.0021 18.0 0.2 0.027 14.4 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KFM28338.1 - 0.0077 16.3 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 KFM28338.1 - 0.18 11.8 0.0 0.42 10.6 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain ubiquitin PF00240.23 KFM28339.1 - 1.3e-07 31.2 0.3 3.4e-07 29.9 0.3 1.6 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 KFM28339.1 - 2.2e-06 28.0 0.1 1.1e-05 25.8 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 KFM28339.1 - 0.032 14.1 0.2 0.15 11.9 0.2 1.8 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Transketolase_C PF02780.20 KFM28341.1 - 1.6e-43 147.5 0.1 3.4e-43 146.5 0.1 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 KFM28341.1 - 6.6e-36 123.6 0.1 1.4e-35 122.6 0.1 1.5 1 1 0 1 1 1 1 Transketolase, pyrimidine binding domain PFOR_II PF17147.4 KFM28341.1 - 0.034 14.5 0.0 0.08 13.3 0.0 1.7 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II CHZ PF09649.10 KFM28342.1 - 3.4e-07 29.6 0.3 7.1e-07 28.6 0.3 1.6 1 0 0 1 1 1 1 Histone chaperone domain CHZ BUD22 PF09073.10 KFM28342.1 - 0.061 12.7 13.0 0.063 12.6 13.0 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 KFM28342.1 - 0.12 10.6 8.1 0.12 10.5 8.1 1.0 1 0 0 1 1 1 0 Nop14-like family CPSF100_C PF13299.6 KFM28342.1 - 0.13 12.4 2.7 0.15 12.3 2.7 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CDC45 PF02724.14 KFM28342.1 - 0.43 8.8 7.4 0.47 8.7 7.4 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.12 KFM28342.1 - 0.77 8.7 3.7 0.81 8.6 3.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DNA_pol_phi PF04931.13 KFM28342.1 - 0.98 7.4 9.3 0.48 8.5 7.6 1.3 2 0 0 2 2 2 0 DNA polymerase phi NOA36 PF06524.12 KFM28342.1 - 2.1 7.6 7.4 2.5 7.3 7.4 1.1 1 0 0 1 1 1 0 NOA36 protein DUF5423 PF17461.2 KFM28342.1 - 2.2 7.1 10.3 3.1 6.6 10.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5423) Presenilin PF01080.17 KFM28342.1 - 4.8 5.9 5.2 5 5.8 5.2 1.1 1 0 0 1 1 1 0 Presenilin FbpA PF05833.11 KFM28343.1 - 3.5e-70 237.0 0.0 4.4e-70 236.7 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_2 PF18297.1 KFM28343.1 - 0.057 13.6 0.0 12 6.2 0.0 2.7 2 1 1 3 3 3 0 NFACT protein RNA binding domain NFACT-R_1 PF05670.13 KFM28343.1 - 0.13 12.9 0.0 1.3 9.7 0.0 2.2 1 1 0 1 1 1 0 NFACT protein RNA binding domain Pyr_redox_2 PF07992.14 KFM28344.1 - 1.2e-48 165.9 0.0 3.4e-48 164.4 0.0 1.6 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KFM28344.1 - 1.9e-30 105.3 0.5 3.3e-30 104.6 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KFM28344.1 - 2e-12 47.5 0.0 2e-12 47.5 0.0 2.6 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFM28344.1 - 0.16 11.1 0.3 0.41 9.7 0.0 1.7 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NIF PF03031.18 KFM28345.1 - 2.5e-37 128.0 0.0 4.4e-37 127.2 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase TP_methylase PF00590.20 KFM28346.1 - 4.3e-12 46.4 0.2 6e-12 46.0 0.2 1.2 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases TruB_C PF09142.11 KFM28346.1 - 0.063 13.1 1.3 0.063 13.1 1.3 2.6 3 0 0 3 3 3 0 tRNA Pseudouridine synthase II, C terminal EGF_2 PF07974.13 KFM28347.1 - 1.8e-05 25.0 21.8 0.02 15.3 12.0 2.9 2 0 0 2 2 2 2 EGF-like domain EGF_alliinase PF04863.13 KFM28347.1 - 0.21 12.0 17.6 0.93 9.9 0.6 3.0 3 0 0 3 3 3 0 Alliinase EGF-like domain EGF_2 PF07974.13 KFM28348.1 - 0.0035 17.7 15.8 0.0035 17.7 15.8 4.1 3 1 0 3 3 3 2 EGF-like domain ABC_membrane PF00664.23 KFM28349.1 - 1.8e-31 109.8 0.2 2.5e-31 109.4 0.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KFM28349.1 - 7.5e-30 104.2 0.0 1.2e-29 103.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KFM28349.1 - 1.9e-09 37.3 0.1 1.6e-07 31.0 0.0 2.1 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 KFM28349.1 - 0.00076 19.1 1.4 0.011 15.3 1.4 2.5 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KFM28349.1 - 0.017 14.9 0.1 0.065 13.0 0.1 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFM28349.1 - 0.033 14.1 0.1 0.064 13.2 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 KFM28349.1 - 0.083 13.2 1.1 0.46 10.7 0.2 2.5 2 1 0 2 2 2 0 AAA domain AAA_21 PF13304.6 KFM28349.1 - 0.17 11.7 0.1 2.7 7.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KFM28349.1 - 9 6.6 11.1 0.26 11.6 3.2 2.5 3 1 0 3 3 3 0 AAA ATPase domain DUF5403 PF17395.2 KFM28350.1 - 0.37 11.1 2.2 3.2 8.1 0.3 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5403) UBM PF14377.6 KFM28350.1 - 1.6 8.3 0.1 1.6 8.3 0.1 2.9 3 0 0 3 3 3 0 Ubiquitin binding region Opiods_neuropep PF01160.18 KFM28351.1 - 0.38 10.9 3.4 8.7 6.5 0.4 2.3 2 0 0 2 2 2 0 Vertebrate endogenous opioids neuropeptide WD40 PF00400.32 KFM28352.1 - 1e-26 92.6 5.3 7.6e-06 26.6 0.0 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM28352.1 - 3e-11 43.5 0.7 6.8e-06 26.3 0.0 4.3 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 KFM28352.1 - 1.7e-10 40.4 0.1 2.7e-10 39.7 0.1 1.3 1 0 0 1 1 1 1 LisH-like dimerisation domain Ge1_WD40 PF16529.5 KFM28352.1 - 5.1e-09 35.5 0.4 0.099 11.6 0.0 3.8 1 1 3 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KFM28352.1 - 0.00066 18.4 0.7 0.013 14.2 0.1 2.1 1 1 1 2 2 2 1 Nucleoporin Nup120/160 IKI3 PF04762.12 KFM28352.1 - 0.11 10.4 0.1 0.16 9.9 0.1 1.1 1 0 0 1 1 1 0 IKI3 family RRM_1 PF00076.22 KFM28353.1 - 3.2e-17 62.1 0.0 4.3e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFM28353.1 - 0.032 14.3 0.0 0.06 13.5 0.0 1.5 1 1 0 1 1 1 0 RNA recognition motif RRM_5 PF13893.6 KFM28353.1 - 0.16 11.6 0.0 0.21 11.2 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fib_alpha PF08702.10 KFM28354.1 - 2.3 8.4 6.7 42 4.3 1.9 3.6 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family RRF PF01765.19 KFM28355.1 - 2.2e-39 135.0 0.1 2.7e-39 134.7 0.1 1.0 1 0 0 1 1 1 1 Ribosome recycling factor Peptidase_M3 PF01432.20 KFM28356.1 - 1.6e-18 67.2 0.0 1.1e-17 64.4 0.0 1.9 1 1 0 1 1 1 1 Peptidase family M3 Peptidase_M2 PF01401.18 KFM28356.1 - 4.4e-05 22.3 0.0 6.2e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Angiotensin-converting enzyme Peptidase_S9_N PF02897.15 KFM28357.1 - 4.2e-89 299.2 0.0 3.8e-48 164.3 0.0 2.1 1 1 1 2 2 2 2 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 KFM28357.1 - 7.1e-60 202.1 0.0 1.2e-59 201.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KFM28357.1 - 0.014 14.7 0.1 0.027 13.8 0.1 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Pkinase_Tyr PF07714.17 KFM28358.1 - 1e-41 143.0 0.0 3.8e-36 124.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KFM28358.1 - 2.7e-32 112.2 0.0 5.1e-32 111.3 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KFM28358.1 - 0.0083 15.5 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFM28358.1 - 0.017 15.1 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFM28358.1 - 0.023 13.5 0.0 0.038 12.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase PGP_phosphatase PF09419.10 KFM28359.1 - 1.3e-39 135.5 0.0 1.8e-39 135.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 KFM28359.1 - 8.6e-07 28.9 0.0 1.6e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 KFM28359.1 - 0.004 17.3 0.0 0.0083 16.2 0.0 1.5 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFM28359.1 - 0.011 16.0 0.0 4.1 7.6 0.0 2.2 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase DUF3337 PF11816.8 KFM28360.1 - 3e-20 72.8 0.0 6e-20 71.8 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 KFM28360.1 - 8.5e-13 48.6 13.4 3.2e-06 27.8 0.0 5.9 5 0 0 5 5 5 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KFM28360.1 - 0.01 14.8 0.0 0.022 13.7 0.0 1.4 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 KFM28360.1 - 0.17 12.2 0.0 2.3 8.6 0.0 2.7 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain SAPS PF04499.15 KFM28361.1 - 3.9e-06 25.9 0.0 0.041 12.7 0.0 3.7 2 1 2 4 4 4 3 SIT4 phosphatase-associated protein zf-HYPF PF07503.12 KFM28361.1 - 0.24 11.2 2.6 0.26 11.1 0.1 2.2 2 0 0 2 2 2 0 HypF finger Glyco_transf_22 PF03901.17 KFM28362.1 - 4.9e-76 256.6 9.1 5.8e-76 256.4 9.1 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DSPc PF00782.20 KFM28362.1 - 0.00047 20.0 0.0 0.00082 19.2 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 KFM28362.1 - 0.0008 19.1 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) ABC2_membrane_5 PF13346.6 KFM28362.1 - 0.55 9.8 3.5 0.25 10.9 0.5 1.9 2 1 0 2 2 2 0 ABC-2 family transporter protein MFS_1 PF07690.16 KFM28363.1 - 3.4e-11 42.7 41.3 2.8e-10 39.6 41.5 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM28363.1 - 2e-05 23.7 8.0 5.2e-05 22.3 7.7 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 KFM28363.1 - 0.22 10.4 3.0 0.41 9.5 3.0 1.4 1 0 0 1 1 1 0 MFS_1 like family V-SNARE_C PF12352.8 KFM28365.1 - 1.2e-08 35.1 0.9 2.4e-08 34.2 0.9 1.5 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KFM28365.1 - 8.8e-05 22.4 3.1 9.1e-05 22.3 0.8 2.1 2 0 0 2 2 2 1 Sec20 FRB_dom PF08771.11 KFM28365.1 - 0.0017 18.8 0.4 0.015 15.7 0.1 2.0 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain V-SNARE PF05008.15 KFM28365.1 - 0.0073 16.7 0.8 0.024 15.0 0.8 1.9 1 1 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus EMP24_GP25L PF01105.24 KFM28365.1 - 0.016 15.1 1.2 0.018 15.0 0.2 1.5 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF2313 PF10076.9 KFM28365.1 - 0.12 12.2 0.1 0.28 11.0 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2313) DUF5345 PF17280.2 KFM28365.1 - 0.31 11.1 4.8 5.4 7.1 0.2 3.2 2 1 1 3 3 3 0 Family of unknown function (DUF5345) RIBIOP_C PF04950.12 KFM28366.1 - 3e-101 338.7 0.0 3.9e-101 338.3 0.0 1.1 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KFM28366.1 - 7.8e-14 51.5 0.0 1.5e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 AARP2CN (NUC121) domain FKBP_C PF00254.28 KFM28367.1 - 0.027 14.8 0.1 0.2 12.0 0.1 2.5 1 1 1 2 2 2 0 FKBP-type peptidyl-prolyl cis-trans isomerase Amidinotransf PF02274.17 KFM28369.1 - 1.5e-49 168.9 0.0 1.8e-49 168.6 0.0 1.1 1 0 0 1 1 1 1 Amidinotransferase Ycf54 PF10674.9 KFM28371.1 - 5.5e-26 90.7 0.0 8e-26 90.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2488) RNA_pol_L_2 PF13656.6 KFM28372.1 - 3.4e-25 87.6 0.0 4.7e-25 87.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KFM28372.1 - 2.3e-08 33.3 0.0 3.8e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Peptidase_C48 PF02902.19 KFM28373.1 - 1.2e-31 110.3 0.0 1.6e-31 109.8 0.0 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Bac_surface_Ag PF01103.23 KFM28374.1 - 1.5e-15 57.5 0.1 5.1e-12 45.9 0.1 2.1 1 1 0 1 1 1 1 Surface antigen OMP_b-brl PF13505.6 KFM28375.1 - 0.13 12.4 4.8 0.22 11.6 4.8 1.5 1 1 0 1 1 1 0 Outer membrane protein beta-barrel domain KRTAP PF11759.8 KFM28375.1 - 0.23 12.0 32.5 51 4.5 32.6 2.2 1 1 0 1 1 1 0 Keratin-associated matrix SGP PF17228.2 KFM28375.1 - 1.3 9.9 8.0 1.6 9.6 8.0 1.1 1 0 0 1 1 1 0 Sulphur globule protein DUF5320 PF17253.2 KFM28375.1 - 1.4 10.1 13.7 2.1 9.5 13.7 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5320) AAA_12 PF13087.6 KFM28376.1 - 7.8e-62 208.4 0.0 1.1e-61 207.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFM28376.1 - 1e-56 192.6 0.0 5.1e-29 101.8 0.1 2.6 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 KFM28376.1 - 2e-10 40.7 0.7 0.0005 19.9 0.4 2.7 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 KFM28376.1 - 8.1e-08 32.3 0.0 0.0083 15.9 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 KFM28376.1 - 1e-05 25.9 0.1 0.087 13.2 0.2 2.5 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.9 KFM28376.1 - 0.021 14.1 0.0 6.4 5.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 KFM28376.1 - 0.031 14.6 0.0 0.099 13.0 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain GP40 PF11025.8 KFM28376.1 - 0.079 12.7 0.0 6.9 6.4 0.0 2.6 2 0 0 2 2 2 0 Glycoprotein GP40 of Cryptosporidium Helicase_RecD PF05127.14 KFM28376.1 - 0.14 12.0 0.0 4.9 7.0 0.0 3.1 4 0 0 4 4 4 0 Helicase Peptidase_S9 PF00326.21 KFM28377.1 - 2.1e-22 79.7 0.1 3.9e-22 78.8 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KFM28377.1 - 1.6e-07 31.2 0.2 4.2e-05 23.3 0.0 2.7 2 1 0 3 3 3 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 KFM28377.1 - 0.00053 20.7 5.6 0.00053 20.7 5.6 3.4 2 1 0 3 3 3 1 Alpha/beta hydrolase family Esterase PF00756.20 KFM28377.1 - 0.00089 19.0 0.6 0.0047 16.6 0.1 2.3 2 1 1 3 3 3 1 Putative esterase Hydrolase_4 PF12146.8 KFM28377.1 - 0.0034 16.7 0.3 0.23 10.7 0.1 2.4 1 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFM28377.1 - 0.019 14.6 0.1 0.11 12.1 0.1 1.8 1 1 1 2 2 2 0 alpha/beta hydrolase fold DLH PF01738.18 KFM28377.1 - 0.084 12.4 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 KFM28377.1 - 0.27 11.0 0.0 0.7 9.7 0.0 1.6 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase SMC_N PF02463.19 KFM28378.1 - 5.6e-60 202.5 0.1 7.3e-60 202.1 0.1 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFM28378.1 - 8.4e-12 45.5 0.3 0.00012 22.0 0.0 2.8 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KFM28378.1 - 3.2e-08 34.3 18.5 5e-05 23.9 18.5 3.8 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KFM28378.1 - 6.1e-07 30.0 0.2 0.012 16.2 0.0 3.3 3 1 0 3 3 3 2 ABC transporter AAA_15 PF13175.6 KFM28378.1 - 6.9e-07 29.3 1.4 6.4e-06 26.1 0.1 3.0 2 2 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KFM28378.1 - 0.0012 18.5 0.0 0.0033 17.1 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain TMF_DNA_bd PF12329.8 KFM28378.1 - 0.0067 16.4 4.5 0.0067 16.4 4.5 5.2 4 2 1 5 5 5 1 TATA element modulatory factor 1 DNA binding NPV_P10 PF05531.12 KFM28378.1 - 0.016 15.7 9.6 3.8 8.0 0.2 5.3 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein DUF2617 PF10936.8 KFM28378.1 - 0.073 13.1 0.6 0.19 11.8 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function DUF2617 LacI PF00356.21 KFM28378.1 - 0.078 12.8 4.4 0.32 10.8 0.1 3.3 3 0 0 3 3 3 0 Bacterial regulatory proteins, lacI family TMCO5 PF14992.6 KFM28378.1 - 0.11 12.1 0.1 0.11 12.1 0.1 3.4 2 1 2 4 4 4 0 TMCO5 family Rod_cone_degen PF15201.6 KFM28378.1 - 0.12 12.5 1.6 12 6.1 0.2 2.7 2 0 0 2 2 2 0 Progressive rod-cone degeneration WDCP PF15390.6 KFM28378.1 - 0.15 10.4 0.4 0.31 9.4 0.2 1.6 1 1 0 1 1 1 0 WD repeat and coiled-coil-containing protein family PKcGMP_CC PF16808.5 KFM28378.1 - 1.7 8.6 10.0 22 5.0 0.2 4.4 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase EF-G-binding_N PF07299.11 KFM28378.1 - 2.8 8.5 4.3 13 6.3 0.4 3.0 2 0 0 2 2 2 0 Elongation factor G-binding protein, N-terminal PI3K_P85_iSH2 PF16454.5 KFM28378.1 - 7.4 6.1 17.8 7.4 6.1 0.7 4.6 3 1 2 5 5 5 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Occludin_ELL PF07303.13 KFM28378.1 - 9.6 7.0 9.4 51 4.7 2.3 4.1 3 2 1 4 4 4 0 Occludin homology domain Vps54 PF07928.12 KFM28379.1 - 7.1e-23 81.5 0.0 1.8e-22 80.2 0.0 1.6 1 0 0 1 1 1 1 Vps54-like protein Aminotran_1_2 PF00155.21 KFM28380.1 - 1e-48 166.3 0.0 1.6e-48 165.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 KFM28380.1 - 0.00087 18.3 0.0 0.0015 17.5 0.0 1.3 1 0 0 1 1 1 1 Allinase TPR_12 PF13424.6 KFM28380.1 - 0.013 15.8 0.7 0.013 15.8 0.7 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat potato_inhibit PF00280.18 KFM28381.1 - 7.2e-15 55.4 0.1 8.6e-15 55.2 0.1 1.1 1 0 0 1 1 1 1 Potato inhibitor I family Inhibitor_I78 PF11720.8 KFM28381.1 - 0.00094 19.2 0.1 0.0012 18.8 0.1 1.3 1 1 0 1 1 1 1 Peptidase inhibitor I78 family PASTA PF03793.19 KFM28381.1 - 0.05 13.5 0.1 0.059 13.2 0.1 1.4 1 1 0 1 1 1 0 PASTA domain DUF1484 PF07363.11 KFM28382.1 - 0.022 15.8 0.5 0.022 15.8 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1484) DUF3613 PF12266.8 KFM28382.1 - 0.037 13.8 0.1 0.26 11.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3613) Mito_fiss_reg PF05308.11 KFM28382.1 - 4 7.5 6.7 2.9 7.9 3.7 1.9 2 0 0 2 2 2 0 Mitochondrial fission regulator CAP_N PF01213.19 KFM28382.1 - 4.1 6.8 6.4 6.6 6.1 6.4 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Cpn60_TCP1 PF00118.24 KFM28383.1 - 3e-93 313.1 14.0 4.6e-93 312.5 14.0 1.3 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family DNA_topoisoIV PF00521.20 KFM28384.1 - 3.9e-130 434.6 0.0 5.1e-130 434.2 0.0 1.1 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.13 KFM28384.1 - 7.3e-38 127.8 11.0 1.5e-07 30.7 0.0 6.4 6 0 0 6 6 6 6 DNA gyrase C-terminal domain, beta-propeller DNA_pol_A_exo1 PF01612.20 KFM28385.1 - 5.1e-10 39.3 0.0 1.8e-09 37.6 0.0 1.8 1 1 0 1 1 1 1 3'-5' exonuclease Trypsin_2 PF13365.6 KFM28387.1 - 7.9e-07 30.1 0.2 1.9e-06 28.9 0.2 1.7 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 KFM28387.1 - 0.033 14.0 2.0 0.089 12.6 0.0 2.2 2 0 0 2 2 2 0 Trypsin TetR_C_30 PF17939.1 KFM28388.1 - 0.018 15.3 1.2 0.49 10.6 0.1 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Chorismate_synt PF01264.21 KFM28389.1 - 4.5e-124 413.4 4.1 2.7e-123 410.9 4.1 1.8 1 1 0 1 1 1 1 Chorismate synthase RNase_HII PF01351.18 KFM28390.1 - 2e-61 207.3 0.0 8.5e-37 126.9 0.0 2.1 1 1 1 2 2 2 2 Ribonuclease HII AvrPtoB_bdg PF16847.5 KFM28390.1 - 0.15 12.5 1.8 18 5.9 0.1 2.3 2 0 0 2 2 2 0 Avirulence AvrPtoB, BAK1-binding domain FANC_SAP PF18081.1 KFM28390.1 - 0.31 11.2 3.5 13 6.0 0.3 2.6 2 0 0 2 2 2 0 Fanconi anemia-associated nuclease SAP domain DNA_pol_phi PF04931.13 KFM28391.1 - 4.7e-68 230.1 0.0 1.7e-57 195.1 0.0 3.8 1 1 1 2 2 2 2 DNA polymerase phi Topo-VIb_trans PF09239.11 KFM28392.1 - 2.8e-49 167.0 0.0 5.2e-49 166.1 0.0 1.4 1 0 0 1 1 1 1 Topoisomerase VI B subunit, transducer HATPase_c_3 PF13589.6 KFM28392.1 - 6.6e-08 32.5 0.2 2.8e-06 27.2 0.0 2.6 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KFM28392.1 - 6.2e-06 26.7 0.0 7.9e-05 23.1 0.0 2.4 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MCU PF04678.13 KFM28393.1 - 4.6e-34 118.0 0.7 7.7e-34 117.3 0.7 1.5 1 1 0 1 1 1 1 Mitochondrial calcium uniporter Rep_1 PF01446.17 KFM28393.1 - 0.077 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Replication protein RRS1 PF04939.12 KFM28394.1 - 3.2e-50 170.2 0.0 6.1e-50 169.2 0.0 1.5 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) Pinin_SDK_memA PF04696.13 KFM28395.1 - 2.1e-14 53.7 1.1 2.3e-14 53.6 0.3 1.4 1 1 0 1 1 1 1 pinin/SDK/memA/ protein conserved region Caskin-Pro-rich PF16907.5 KFM28395.1 - 0.077 13.5 2.2 0.14 12.7 0.0 2.2 2 0 0 2 2 2 0 Proline rich region of Caskin proteins Tfb5 PF06331.12 KFM28396.1 - 8.3e-19 67.3 0.1 1e-18 67.1 0.1 1.1 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 DNA_repr_REX1B PF14966.6 KFM28397.1 - 1.5e-12 48.0 0.0 1.2e-10 41.8 0.0 2.2 2 0 0 2 2 2 2 DNA repair REX1-B Inositol_P PF00459.25 KFM28398.1 - 4.1e-51 174.1 0.0 5e-51 173.8 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.20 KFM28398.1 - 0.0018 17.8 0.0 0.0029 17.1 0.0 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Thyroglobulin_1 PF00086.18 KFM28398.1 - 0.037 13.7 0.2 0.17 11.6 0.0 2.2 2 0 0 2 2 2 0 Thyroglobulin type-1 repeat UPF0051 PF01458.17 KFM28399.1 - 2.8e-66 223.3 0.1 3.6e-66 223.0 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) SpoU_methylase PF00588.19 KFM28401.1 - 8.3e-10 39.0 0.0 9.6e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 SpoU rRNA Methylase family Lyase_1 PF00206.20 KFM28402.1 - 5.2e-80 269.2 0.0 5.4e-46 157.4 0.0 2.2 1 1 1 2 2 2 2 Lyase ASL_C2 PF14698.6 KFM28402.1 - 9.6e-25 87.1 0.1 2.2e-24 86.0 0.1 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal FR47 PF08445.10 KFM28402.1 - 0.046 13.7 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Peptidase_C1 PF00112.23 KFM28403.1 - 1.6e-44 152.6 1.3 2.2e-44 152.1 1.3 1.2 1 0 0 1 1 1 1 Papain family cysteine protease zf_Rg PF17915.1 KFM28403.1 - 0.00095 18.5 0.5 1.3 8.4 0.2 2.5 2 0 0 2 2 2 2 Reverse gyrase zinc finger Peptidase_C1_2 PF03051.15 KFM28403.1 - 0.079 11.7 0.4 0.15 10.8 0.4 1.4 1 0 0 1 1 1 0 Peptidase C1-like family Pro_isomerase PF00160.21 KFM28404.1 - 2e-41 141.9 0.0 2.9e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 KFM28404.1 - 4.5e-15 55.2 0.0 9.7e-15 54.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TLC PF03219.14 KFM28405.1 - 5.9e-196 652.0 12.9 7.4e-196 651.6 12.9 1.0 1 0 0 1 1 1 1 TLC ATP/ADP transporter SSURE PF11966.8 KFM28405.1 - 0.097 12.4 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Fibronectin-binding repeat Cupin_8 PF13621.6 KFM28406.1 - 4.2e-40 138.1 0.0 5.9e-40 137.6 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain SPC22 PF04573.12 KFM28406.1 - 3.1e-28 98.4 0.0 4.4e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 Signal peptidase subunit Cupin_4 PF08007.12 KFM28406.1 - 0.019 14.4 0.0 0.12 11.9 0.0 2.1 2 0 0 2 2 2 0 Cupin superfamily protein JmjC PF02373.22 KFM28406.1 - 0.024 15.1 0.0 0.085 13.3 0.0 1.9 1 0 0 1 1 1 0 JmjC domain, hydroxylase Cupin_2 PF07883.11 KFM28406.1 - 0.21 11.3 0.5 0.79 9.5 0.0 2.1 2 0 0 2 2 2 0 Cupin domain WD40 PF00400.32 KFM28407.1 - 5.5e-05 23.8 1.4 0.16 12.9 0.4 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM28407.1 - 0.0031 17.8 0.0 3.3 8.1 0.0 2.6 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFM28407.1 - 0.092 11.7 0.0 0.23 10.4 0.0 1.6 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PEPcase PF00311.17 KFM28408.1 - 8e-269 894.0 0.1 1.1e-268 893.6 0.1 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase FRB_dom PF08771.11 KFM28408.1 - 0.0005 20.4 0.1 0.29 11.6 0.0 2.9 2 0 0 2 2 2 2 FKBP12-rapamycin binding domain FTA4 PF13093.6 KFM28408.1 - 0.0044 16.9 0.6 0.0087 16.0 0.6 1.5 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 MAP65_ASE1 PF03999.12 KFM28408.1 - 0.05 12.3 1.8 0.077 11.7 1.8 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) FlxA PF14282.6 KFM28408.1 - 0.48 10.5 1.3 1.9 8.5 0.9 2.1 2 0 0 2 2 2 0 FlxA-like protein GCP_C_terminal PF04130.13 KFM28409.1 - 3.4e-52 177.8 0.0 8.2e-52 176.6 0.0 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KFM28409.1 - 3.2e-17 63.1 0.0 1.6e-10 41.1 0.0 2.5 1 1 1 2 2 2 2 Gamma tubulin complex component N-terminal UQ_con PF00179.26 KFM28411.1 - 1.4e-41 141.4 0.0 1.6e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFM28411.1 - 0.011 16.1 0.0 0.027 14.8 0.0 1.7 1 1 1 2 2 2 0 RWD domain UEV PF05743.13 KFM28411.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.5 1 1 0 1 1 1 0 UEV domain Glyoxalase PF00903.25 KFM28412.1 - 3.2e-06 27.4 0.0 5.7e-06 26.5 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KFM28412.1 - 0.00033 21.4 0.0 0.00039 21.2 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain DUF1084 PF06454.11 KFM28413.1 - 9.2e-120 399.1 2.3 1e-119 398.9 2.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) DUF4153 PF13687.6 KFM28413.1 - 0.00014 21.6 3.1 0.00014 21.6 3.1 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4153) Cu_amine_oxid PF01179.20 KFM28415.1 - 8.5e-140 466.3 0.0 6.2e-98 328.4 0.0 2.1 1 1 1 2 2 2 2 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KFM28415.1 - 3.3e-10 40.2 0.0 7.2e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KFM28415.1 - 1.8e-07 31.3 0.0 3.9e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Chorion_S16 PF05836.12 KFM28415.1 - 0.046 13.9 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 Chorion protein S16 Ribosomal_L3 PF00297.22 KFM28416.1 - 5.5e-20 71.7 1.4 4.9e-18 65.3 0.5 2.1 1 1 1 2 2 2 2 Ribosomal protein L3 zf-CCCH_3 PF15663.5 KFM28417.1 - 6.1e-15 55.4 4.6 2.4e-07 31.0 0.3 2.3 1 1 1 2 2 2 2 Zinc-finger containing family zf_CCCH_4 PF18345.1 KFM28417.1 - 4.9e-12 45.5 16.5 1.1e-06 28.5 1.2 2.9 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH PF00642.24 KFM28417.1 - 1.4e-07 31.2 11.3 0.00021 21.1 0.7 3.0 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KFM28417.1 - 1.7e-07 31.9 6.0 0.0018 19.0 0.5 2.3 1 1 1 2 2 2 2 Torus domain zf-CCCH_2 PF14608.6 KFM28417.1 - 9.3e-05 22.8 19.4 0.0054 17.2 1.4 3.5 3 0 0 3 3 3 2 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 KFM28417.1 - 0.061 13.2 8.4 1.1 9.1 1.0 2.6 2 0 0 2 2 2 0 CCCH-type zinc finger Peptidase_C1 PF00112.23 KFM28418.1 - 5.4e-52 177.0 0.1 8.1e-52 176.5 0.1 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 KFM28418.1 - 3.9e-13 49.6 0.0 6e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 KFM28418.1 - 0.046 12.5 0.1 0.11 11.2 0.1 1.5 1 0 0 1 1 1 0 Peptidase C1-like family SIS_2 PF13580.6 KFM28418.1 - 0.085 12.9 0.0 0.25 11.4 0.0 1.7 2 0 0 2 2 2 0 SIS domain SHMT PF00464.19 KFM28420.1 - 9.2e-190 630.4 0.0 1.1e-189 630.1 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 KFM28420.1 - 0.017 14.4 0.1 0.049 12.9 0.1 1.8 1 1 0 1 1 1 0 Beta-eliminating lyase Aminotran_5 PF00266.19 KFM28420.1 - 0.11 11.4 0.5 1.1 8.1 0.5 2.0 1 1 0 1 1 1 0 Aminotransferase class-V Helicase_C PF00271.31 KFM28421.1 - 3.7e-15 56.2 0.0 8.3e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RNase_T PF00929.24 KFM28421.1 - 8.5e-09 36.2 0.0 1.3e-08 35.6 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DEAD PF00270.29 KFM28421.1 - 7.8e-06 25.8 0.0 0.0013 18.5 0.1 2.3 1 1 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 KFM28421.1 - 1.6e-05 24.9 0.0 0.084 12.9 0.0 2.2 1 1 1 2 2 2 2 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KFM28421.1 - 0.00048 19.9 0.9 0.00048 19.9 0.9 2.1 2 0 0 2 2 2 1 AAA domain WD40 PF00400.32 KFM28422.1 - 9.8e-49 162.3 4.8 6.9e-08 33.0 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM28422.1 - 3.3e-15 56.2 0.0 1.3e-06 28.6 0.0 5.0 1 1 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFM28422.1 - 4.7e-05 22.5 0.0 0.66 8.9 0.0 3.8 2 2 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KFM28422.1 - 0.00011 21.0 0.4 2.6 6.6 0.0 3.2 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Frtz PF11768.8 KFM28422.1 - 0.23 9.7 0.0 7.2 4.8 0.0 2.7 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Isy1 PF06246.12 KFM28423.1 - 8.4e-90 300.8 5.3 9.7e-90 300.6 5.3 1.0 1 0 0 1 1 1 1 Isy1-like splicing family PX PF00787.24 KFM28426.1 - 3.4e-48 162.3 0.0 1e-22 80.2 0.0 2.2 2 0 0 2 2 2 2 PX domain DUF43 PF01861.16 KFM28426.1 - 7.7e-05 22.0 0.0 0.33 10.1 0.0 2.2 2 0 0 2 2 2 2 Branched-chain polyamine synthase A C-terminal domain DUF2436 PF10365.9 KFM28426.1 - 0.036 13.8 0.0 5.7 6.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2436) DUF1730 PF08331.10 KFM28426.1 - 0.054 13.4 0.0 18 5.3 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1730) Vps53_N PF04100.12 KFM28426.1 - 0.065 12.2 0.1 9.5 5.1 0.0 2.1 2 0 0 2 2 2 0 Vps53-like, N-terminal fn3 PF00041.21 KFM28426.1 - 0.12 12.8 0.0 26 5.2 0.0 2.3 2 0 0 2 2 2 0 Fibronectin type III domain AKAP7_NLS PF10469.9 KFM28426.1 - 0.13 12.1 0.0 23 4.8 0.0 2.3 2 0 0 2 2 2 0 AKAP7 2'5' RNA ligase-like domain JAB PF01398.21 KFM28427.1 - 4.5e-13 49.2 0.2 6.6e-13 48.7 0.2 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DHBP_synthase PF00926.19 KFM28428.1 - 3.7e-72 241.9 0.3 4.8e-72 241.5 0.3 1.1 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Asn_synthase PF00733.21 KFM28429.1 - 6e-86 289.3 1.2 8.8e-55 186.8 0.2 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KFM28429.1 - 9.6e-26 90.1 0.0 1.4e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KFM28429.1 - 9.4e-19 67.9 0.0 1.6e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KFM28429.1 - 1.8e-07 30.9 0.0 3.7e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein tRNA_Me_trans PF03054.16 KFM28429.1 - 0.0035 16.2 0.0 0.0052 15.6 0.0 1.1 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.17 KFM28429.1 - 0.012 14.7 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 NAD synthase Abhydrolase_7 PF12715.7 KFM28429.1 - 0.23 10.7 0.0 0.34 10.1 0.0 1.1 1 0 0 1 1 1 0 Abhydrolase family ABC_tran PF00005.27 KFM28430.1 - 6.9e-21 75.2 0.0 1e-20 74.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter Ribosomal_L33 PF00471.20 KFM28430.1 - 1.6e-19 70.0 1.1 2.7e-19 69.3 1.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L33 RsgA_GTPase PF03193.16 KFM28430.1 - 0.001 19.0 0.0 0.0021 18.0 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 KFM28430.1 - 0.0016 18.1 0.0 0.0038 16.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KFM28430.1 - 0.0025 17.5 0.1 0.0055 16.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.6 KFM28430.1 - 0.013 15.7 0.3 0.1 12.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KFM28430.1 - 0.019 15.3 0.0 0.043 14.2 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 KFM28430.1 - 0.031 14.0 0.1 0.051 13.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KFM28430.1 - 0.057 13.7 1.3 0.083 13.1 0.3 1.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KFM28430.1 - 0.062 13.8 0.1 0.13 12.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain DUF5544 PF17698.1 KFM28430.1 - 0.062 13.4 0.7 0.18 11.9 0.3 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5544) AAA_21 PF13304.6 KFM28430.1 - 0.088 12.6 0.0 0.17 11.7 0.0 1.5 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KFM28430.1 - 0.16 12.2 0.1 0.51 10.6 0.1 1.8 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 KFM28430.1 - 0.2 11.2 0.1 0.35 10.4 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Adaptin_N PF01602.20 KFM28431.1 - 3.3e-65 220.6 0.0 1.3e-39 136.2 0.1 2.1 1 1 1 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 KFM28431.1 - 3.6e-05 23.9 2.3 0.0007 19.7 0.0 3.6 1 1 2 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KFM28431.1 - 0.0053 16.9 4.1 0.38 11.1 0.0 4.8 3 1 1 5 5 5 1 HEAT repeat Ribosomal_S10 PF00338.22 KFM28433.1 - 1.2e-33 115.2 0.1 1.4e-33 115.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Phage_holin_1 PF04531.13 KFM28433.1 - 0.079 13.5 0.0 0.12 12.9 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage holin NGP1NT PF08153.12 KFM28434.1 - 5.7e-44 149.4 0.1 8.6e-44 148.8 0.1 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 KFM28434.1 - 6.2e-17 61.7 0.0 5.6e-14 52.2 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase PGAP1 PF07819.13 KFM28434.1 - 5.4e-15 55.7 0.0 5.4e-12 45.9 0.0 2.2 2 0 0 2 2 2 2 PGAP1-like protein FeoB_N PF02421.18 KFM28434.1 - 4e-07 29.7 0.2 2.3e-05 24.0 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KFM28434.1 - 0.00044 20.2 0.0 0.00094 19.1 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 KFM28434.1 - 0.0095 16.0 0.4 2.4 8.2 0.1 3.2 2 1 1 3 3 3 1 Dynamin family Arf PF00025.21 KFM28434.1 - 0.096 12.1 0.1 8.6 5.8 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF2838 PF10998.8 KFM28435.1 - 4.6e-32 110.6 11.5 4.6e-32 110.6 11.5 2.3 2 1 0 3 3 3 1 Protein of unknown function (DUF2838) tRNA-synt_2d PF01409.20 KFM28436.1 - 1.1e-47 162.6 0.0 1.8e-47 161.9 0.0 1.3 1 1 0 1 1 1 1 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 KFM28436.1 - 1.1e-25 89.8 0.0 2.2e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Abhydrolase_1 PF00561.20 KFM28437.1 - 1.9e-11 44.1 0.4 0.00099 18.8 0.1 3.1 2 1 1 3 3 3 3 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFM28437.1 - 1e-10 41.3 0.0 2.4e-10 40.1 0.1 1.6 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFM28437.1 - 1.5e-07 32.3 7.6 5.9e-07 30.3 5.8 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 KFM28437.1 - 2.5e-06 27.5 0.0 4.2e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Thioesterase PF00975.20 KFM28437.1 - 0.0019 18.3 0.0 0.0031 17.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Peptidase_S9 PF00326.21 KFM28437.1 - 0.0024 17.4 0.0 0.057 12.9 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family FSH1 PF03959.13 KFM28437.1 - 0.12 12.0 0.0 0.74 9.4 0.0 2.2 2 1 0 2 2 2 0 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 KFM28437.1 - 0.15 11.9 0.3 0.31 10.9 0.3 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.20 KFM28437.1 - 0.35 10.5 1.0 0.68 9.5 0.8 1.6 1 1 0 1 1 1 0 Putative esterase Hydrolase_4 PF12146.8 KFM28438.1 - 1.9e-06 27.4 0.0 2.1e-06 27.2 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFM28438.1 - 0.00013 21.7 0.0 0.041 13.5 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KFM28438.1 - 0.013 15.6 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Abhydrolase_1 PF00561.20 KFM28439.1 - 0.00055 19.7 0.0 0.00071 19.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFM28439.1 - 0.0058 15.9 0.1 0.0072 15.6 0.1 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 NIF PF03031.18 KFM28440.1 - 1.1e-18 67.5 0.0 1.6e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.7 KFM28440.1 - 0.00039 20.3 0.1 0.0014 18.6 0.1 1.8 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.26 KFM28440.1 - 0.0013 19.0 0.0 0.0023 18.3 0.0 1.3 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain RFC1 PF08519.12 KFM28442.1 - 1.5e-45 155.2 0.0 2.8e-45 154.3 0.0 1.5 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 KFM28442.1 - 2.4e-15 56.6 0.0 5.3e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 KFM28442.1 - 5.4e-12 46.3 0.0 1e-10 42.1 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KFM28442.1 - 9.2e-05 22.4 0.1 0.0076 16.2 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_22 PF13401.6 KFM28442.1 - 0.00041 20.6 1.0 0.002 18.4 0.0 2.7 3 0 0 3 3 3 1 AAA domain PTCB-BRCT PF12738.7 KFM28442.1 - 0.0016 18.4 0.0 0.0038 17.1 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain RuvB_N PF05496.12 KFM28442.1 - 0.0027 17.5 0.0 0.0063 16.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 KFM28442.1 - 0.004 17.2 0.0 0.0099 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain HHH PF00633.23 KFM28442.1 - 0.01 15.6 0.1 1.2 9.1 0.1 2.8 2 0 0 2 2 2 0 Helix-hairpin-helix motif AAA_33 PF13671.6 KFM28442.1 - 0.011 15.8 0.1 0.011 15.8 0.1 4.0 2 2 1 3 3 2 0 AAA domain TIP49 PF06068.13 KFM28442.1 - 0.016 14.4 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain NTPase_1 PF03266.15 KFM28442.1 - 0.018 15.0 0.0 0.15 11.9 0.0 2.4 1 1 0 1 1 1 0 NTPase AAA_16 PF13191.6 KFM28442.1 - 0.027 14.9 0.2 0.027 14.9 0.2 5.5 3 2 1 4 4 3 0 AAA ATPase domain CbiA PF01656.23 KFM28442.1 - 0.047 13.8 0.1 0.14 12.2 0.1 1.8 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DEAD PF00270.29 KFM28442.1 - 0.071 12.9 0.1 14 5.4 0.0 2.5 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_19 PF13245.6 KFM28442.1 - 0.08 13.3 0.1 0.08 13.3 0.1 3.4 3 1 0 3 3 2 0 AAA domain AAA_11 PF13086.6 KFM28442.1 - 0.086 12.6 0.0 0.086 12.6 0.0 4.4 3 1 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 KFM28442.1 - 0.14 12.6 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 KFM28442.1 - 0.14 11.8 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFM28442.1 - 2 8.9 8.6 7.8 7.0 0.0 4.4 4 1 1 5 5 5 0 ABC transporter DUF4375 PF14300.6 KFM28443.1 - 0.022 15.0 0.1 0.029 14.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4375) Methyltransf_16 PF10294.9 KFM28444.1 - 2.5e-21 76.2 0.0 4.3e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase F-box-like PF12937.7 KFM28444.1 - 1.8e-05 24.5 0.2 3.6e-05 23.6 0.2 1.5 1 0 0 1 1 1 1 F-box-like Methyltransf_23 PF13489.6 KFM28444.1 - 0.013 15.3 0.0 0.062 13.1 0.0 1.9 1 1 1 2 2 2 0 Methyltransferase domain F-box PF00646.33 KFM28444.1 - 0.054 13.4 0.4 0.15 12.0 0.4 1.8 1 0 0 1 1 1 0 F-box domain MTS PF05175.14 KFM28444.1 - 0.061 12.9 0.0 0.084 12.4 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase small domain PRANC PF09372.10 KFM28444.1 - 0.093 13.1 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 PRANC domain F-box_4 PF15966.5 KFM28444.1 - 0.19 11.6 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 F-box WD40 PF00400.32 KFM28446.1 - 1.4e-18 66.9 1.4 5.1e-06 27.1 0.1 5.1 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM28446.1 - 3.2e-09 37.0 0.0 0.39 11.0 0.0 4.8 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain ER_lumen_recept PF00810.18 KFM28447.1 - 1.2e-36 126.7 1.3 1.2e-36 126.7 1.3 1.8 3 0 0 3 3 3 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KFM28447.1 - 0.00073 19.2 0.5 0.51 10.2 0.1 2.6 2 0 0 2 2 2 2 PQ loop repeat T2SSM PF04612.12 KFM28447.1 - 0.016 15.3 0.2 0.026 14.6 0.2 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M DUF1286 PF06939.11 KFM28447.1 - 0.057 13.7 4.1 2.4 8.5 0.1 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF1286) Arf PF00025.21 KFM28449.1 - 1.8e-34 118.7 0.0 2.3e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFM28449.1 - 3.3e-06 27.3 0.0 5.2e-06 26.7 0.0 1.4 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KFM28449.1 - 2.4e-05 23.6 0.0 0.15 11.2 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 KFM28449.1 - 6.7e-05 23.0 0.0 9e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 KFM28449.1 - 0.00061 19.4 0.0 0.0015 18.2 0.0 1.6 1 1 0 1 1 1 1 Ras family SRPRB PF09439.10 KFM28449.1 - 0.0011 18.4 0.0 0.0015 18.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KFM28449.1 - 0.23 10.8 0.0 0.39 10.0 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Pkinase_Tyr PF07714.17 KFM28450.1 - 6.9e-25 87.8 0.0 9.4e-19 67.7 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KFM28450.1 - 5.8e-21 75.0 0.0 1.4e-14 54.1 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain PB1 PF00564.24 KFM28450.1 - 0.21 11.5 0.0 5.8 6.9 0.0 2.4 1 1 0 1 1 1 0 PB1 domain Pkinase PF00069.25 KFM28452.1 - 8.2e-30 104.0 0.0 3.6e-29 101.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM28452.1 - 2.8e-19 69.4 0.0 1.5e-18 67.1 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 KFM28452.1 - 0.012 15.8 0.0 0.031 14.5 0.0 1.6 1 0 0 1 1 1 0 Oxidative-stress-responsive kinase 1 C-terminal domain TPH PF13868.6 KFM28453.1 - 0.49 8.8 27.3 0.71 8.3 18.6 2.0 2 0 0 2 2 2 0 Trichohyalin-plectin-homology domain Kinesin PF00225.23 KFM28454.1 - 1.3e-72 244.6 0.1 2.9e-48 164.5 0.0 2.5 2 1 1 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 KFM28454.1 - 1.5e-12 47.7 0.0 2.6e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding HhH-GPD PF00730.25 KFM28454.1 - 0.018 15.5 0.0 0.1 13.1 0.0 2.3 2 0 0 2 2 2 0 HhH-GPD superfamily base excision DNA repair protein SNF2_N PF00176.23 KFM28455.1 - 1.9e-54 184.7 0.7 1.9e-52 178.1 0.7 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFM28455.1 - 1.3e-14 54.5 0.0 2.4e-13 50.4 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFM28455.1 - 1.6e-06 28.0 0.1 7.6e-06 25.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase QLQ PF08880.11 KFM28455.1 - 2.5e-06 27.1 0.2 8.6e-06 25.4 0.2 2.0 1 0 0 1 1 1 1 QLQ DUF2075 PF09848.9 KFM28455.1 - 0.033 13.4 0.4 0.082 12.1 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Clathrin_H_link PF13838.6 KFM28455.1 - 5.7 6.9 6.4 5.1 7.1 0.2 3.0 2 0 0 2 2 2 0 Clathrin-H-link HR1 PF02185.16 KFM28456.1 - 0.02 15.0 1.9 0.02 15.0 1.9 3.2 4 0 0 4 4 4 0 Hr1 repeat BST2 PF16716.5 KFM28456.1 - 2.9 8.5 14.7 4.5 7.9 0.7 3.7 2 1 0 3 3 3 0 Bone marrow stromal antigen 2 ATG16 PF08614.11 KFM28456.1 - 4.7 7.4 34.8 0.9 9.7 5.4 3.8 3 1 1 4 4 4 0 Autophagy protein 16 (ATG16) HMMR_C PF15908.5 KFM28456.1 - 7.9 6.7 10.8 12 6.2 0.2 3.1 3 0 0 3 3 3 0 Hyaluronan mediated motility receptor C-terminal G_path_suppress PF15991.5 KFM28457.1 - 6.1e-05 23.3 3.8 6.1e-05 23.3 3.8 2.4 2 1 0 2 2 2 1 G-protein pathway suppressor TTKRSYEDQ PF10212.9 KFM28457.1 - 0.057 12.4 1.4 0.071 12.1 1.4 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein DUF4407 PF14362.6 KFM28457.1 - 0.23 10.8 13.2 0.38 10.1 13.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) VSG_B PF13206.6 KFM28457.1 - 0.73 9.0 13.9 1 8.5 13.9 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain SBP_bac_6 PF13343.6 KFM28458.1 - 1.2e-10 41.2 0.0 2.3e-10 40.3 0.0 1.4 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 KFM28458.1 - 0.0013 18.6 0.0 0.0025 17.7 0.0 1.4 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein DUF4602 PF15375.6 KFM28460.1 - 5.1e-18 65.7 3.5 1.1e-17 64.6 3.5 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4602) Pkinase PF00069.25 KFM28461.1 - 2.9e-66 223.5 0.0 3.5e-66 223.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM28461.1 - 2.7e-40 138.3 0.0 3.7e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KFM28461.1 - 0.00023 20.8 0.0 0.00034 20.3 0.0 1.1 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KFM28461.1 - 0.00049 19.5 0.0 0.00076 18.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFM28461.1 - 0.0044 17.0 0.4 0.0044 17.0 0.4 4.0 2 1 2 4 4 4 2 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KFM28461.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL FA_desaturase PF00487.24 KFM28462.1 - 1.9e-30 106.5 15.7 1.9e-30 106.5 15.7 1.9 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 KFM28462.1 - 1.1e-06 28.7 0.0 2.4e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Aminotran_1_2 PF00155.21 KFM28465.1 - 2.1e-24 86.4 0.0 2.5e-24 86.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KFM28465.1 - 4e-07 29.2 0.0 5.2e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase OSCP PF00213.18 KFM28466.1 - 2e-46 158.2 0.4 8.7e-46 156.2 0.9 1.8 2 0 0 2 2 2 1 ATP synthase delta (OSCP) subunit Homoserine_dh PF00742.19 KFM28466.1 - 2.5e-40 138.2 0.0 9.9e-40 136.3 0.0 2.0 3 0 0 3 3 3 1 Homoserine dehydrogenase AA_kinase PF00696.28 KFM28466.1 - 1.4e-31 109.9 0.0 3.2e-31 108.8 0.0 1.6 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.25 KFM28466.1 - 7.8e-17 60.8 1.0 2.2e-08 33.7 0.1 3.2 3 0 0 3 3 3 2 ACT domain ACT_7 PF13840.6 KFM28466.1 - 6.2e-16 58.0 1.4 1.4e-07 31.2 0.4 2.6 2 0 0 2 2 2 2 ACT domain NAD_binding_3 PF03447.16 KFM28466.1 - 1.3e-09 38.7 0.0 6.2e-09 36.5 0.0 2.2 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain TPR_MLP1_2 PF07926.12 KFM28467.1 - 0.0098 16.0 10.6 0.017 15.2 10.6 1.4 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein DUF3584 PF12128.8 KFM28467.1 - 0.011 13.3 6.6 0.014 12.9 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) LXG PF04740.12 KFM28467.1 - 0.012 15.4 4.2 0.019 14.7 4.2 1.2 1 0 0 1 1 1 0 LXG domain of WXG superfamily SPICE PF15678.5 KFM28467.1 - 0.012 15.0 5.2 0.018 14.4 5.2 1.2 1 0 0 1 1 1 0 Centriole duplication and mitotic chromosome congression CLZ PF16526.5 KFM28467.1 - 0.035 14.5 6.3 0.062 13.7 1.8 2.4 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Glyco_H_20C_C PF18088.1 KFM28467.1 - 0.056 13.3 2.3 0.075 12.9 2.3 1.1 1 0 0 1 1 1 0 Glycoside Hydrolase 20C C-terminal domain DUF677 PF05055.12 KFM28467.1 - 0.069 12.0 5.3 0.1 11.5 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) DUF812 PF05667.11 KFM28467.1 - 0.083 11.8 8.2 0.12 11.2 8.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) RasGAP_C PF03836.15 KFM28467.1 - 0.096 12.8 6.8 5.7 7.1 6.8 2.1 1 1 0 1 1 1 0 RasGAP C-terminus HIP1_clath_bdg PF16515.5 KFM28467.1 - 0.11 13.1 10.5 0.19 12.4 9.8 1.7 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1206 PF06724.11 KFM28467.1 - 0.22 11.6 8.3 1.6 8.8 4.0 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) ALMT PF11744.8 KFM28467.1 - 0.26 10.1 2.3 0.3 9.9 2.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter CorA PF01544.18 KFM28467.1 - 0.26 10.5 4.7 0.6 9.4 4.6 1.6 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein TetR_C_16 PF17920.1 KFM28467.1 - 0.29 11.4 4.4 0.43 10.8 1.0 2.6 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Exonuc_VII_L PF02601.15 KFM28467.1 - 0.38 10.3 5.8 0.6 9.6 5.8 1.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit Allexi_40kDa PF05549.11 KFM28467.1 - 0.49 9.9 1.7 0.64 9.5 1.7 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein AAR2 PF05282.11 KFM28467.1 - 0.58 9.5 2.9 0.87 8.9 2.9 1.1 1 0 0 1 1 1 0 AAR2 protein APG6_N PF17675.1 KFM28467.1 - 0.85 10.2 13.4 0.37 11.3 3.1 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region BRE1 PF08647.11 KFM28467.1 - 0.97 9.5 11.0 0.94 9.6 4.8 2.2 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Atg14 PF10186.9 KFM28467.1 - 1 8.4 5.5 1.6 7.8 5.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FAM76 PF16046.5 KFM28467.1 - 1.4 8.2 5.4 1.8 7.9 5.4 1.2 1 0 0 1 1 1 0 FAM76 protein LMBR1 PF04791.16 KFM28467.1 - 1.5 7.6 3.6 2 7.2 3.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein HAUS6_N PF14661.6 KFM28467.1 - 1.7 8.2 8.0 2.7 7.5 8.0 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus MRPL52 PF18699.1 KFM28467.1 - 2.1 8.6 8.2 1.3 9.2 1.6 2.3 1 1 1 2 2 2 0 Mitoribosomal protein mL52 DivIC PF04977.15 KFM28467.1 - 3.3 7.6 9.7 0.94 9.3 1.5 2.3 2 0 0 2 2 2 0 Septum formation initiator Cdh1_DBD_1 PF18196.1 KFM28467.1 - 7.3 6.9 9.9 1.9 8.8 3.4 2.2 1 1 1 2 2 2 0 Chromodomain helicase DNA-binding domain 1 Fib_alpha PF08702.10 KFM28467.1 - 9.6 6.4 7.6 18 5.5 7.6 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family CTD_bind PF04818.13 KFM28468.1 - 7.9e-15 55.4 0.0 1.4e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CTK3 PF12243.8 KFM28468.1 - 0.028 14.4 0.0 0.045 13.8 0.0 1.2 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 PP2C PF00481.21 KFM28469.1 - 1.2e-18 67.7 0.0 1.9e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KFM28469.1 - 0.0043 17.0 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) LRR_4 PF12799.7 KFM28470.1 - 0.0045 17.4 0.5 0.16 12.5 0.2 2.8 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) Tam41_Mmp37 PF09139.11 KFM28471.1 - 2.4e-67 227.7 0.0 1.9e-42 145.8 0.0 2.0 1 1 1 2 2 2 2 Phosphatidate cytidylyltransferase, mitochondrial AMP-binding PF00501.28 KFM28472.1 - 1.4e-17 63.4 0.0 1.8e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme tRNA_m1G_MT PF01746.21 KFM28473.1 - 4.2e-19 69.0 0.1 4.2e-19 69.0 0.1 1.8 2 1 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase CAF-1_p150 PF11600.8 KFM28473.1 - 0.015 15.0 20.2 0.031 14.0 20.2 1.6 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF572 PF04502.13 KFM28473.1 - 0.067 12.8 9.1 0.069 12.8 9.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4670 PF15709.5 KFM28473.1 - 0.11 11.8 22.8 0.31 10.3 22.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4670) HEAT_2 PF13646.6 KFM28474.1 - 0.00013 22.3 5.3 0.36 11.3 0.2 3.6 2 2 1 3 3 3 3 HEAT repeats HEAT_EZ PF13513.6 KFM28474.1 - 0.14 12.7 10.2 11 6.7 0.7 4.4 4 0 0 4 4 4 0 HEAT-like repeat PFK PF00365.20 KFM28475.1 - 4.5e-54 183.7 0.0 5.6e-54 183.4 0.0 1.1 1 0 0 1 1 1 1 Phosphofructokinase MoCF_biosynth PF00994.24 KFM28475.1 - 0.0087 15.7 0.3 0.24 11.1 0.1 2.4 1 1 1 2 2 2 1 Probable molybdopterin binding domain PrsW-protease PF13367.6 KFM28475.1 - 0.5 9.8 3.4 0.13 11.7 0.3 1.6 2 0 0 2 2 2 0 PrsW family intramembrane metalloprotease Nup192 PF11894.8 KFM28476.1 - 7.6e-10 36.6 0.0 5.2e-05 20.6 0.0 3.3 3 0 0 3 3 3 3 Nuclear pore complex scaffold, nucleoporins 186/192/205 SdrD_B PF17210.3 KFM28477.1 - 6.6e-05 23.1 0.0 9.9e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 SdrD B-like domain CarboxypepD_reg PF13620.6 KFM28477.1 - 0.0014 18.9 0.0 0.007 16.6 0.0 2.0 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain PAH PF02671.21 KFM28479.1 - 8.3e-30 102.7 2.1 9.1e-18 64.1 0.6 2.1 2 0 0 2 2 2 2 Paired amphipathic helix repeat Med28 PF11594.8 KFM28479.1 - 0.17 11.9 0.0 0.31 11.1 0.0 1.4 1 1 0 1 1 1 0 Mediator complex subunit 28 Sec23_trunk PF04811.15 KFM28481.1 - 6.3e-30 104.5 0.0 1.4e-14 54.3 0.0 2.1 1 1 1 2 2 2 2 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KFM28481.1 - 1.7e-22 79.9 0.0 3.5e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 KFM28481.1 - 1.2e-20 73.3 0.0 2.7e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 KFM28481.1 - 8.8e-16 57.7 1.1 1.9e-15 56.6 1.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KFM28481.1 - 6.1e-14 51.7 0.0 1.4e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat VWA_2 PF13519.6 KFM28481.1 - 0.01 16.5 0.0 0.061 14.0 0.0 2.1 2 0 0 2 2 2 0 von Willebrand factor type A domain DnaG_DnaB_bind PF08278.11 KFM28481.1 - 0.11 13.1 0.2 2.3 8.8 0.0 2.4 2 0 0 2 2 2 0 DNA primase DnaG DnaB-binding MFS_1 PF07690.16 KFM28483.1 - 4.1e-16 58.8 60.8 4.3e-15 55.5 52.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_4 PF01565.23 KFM28484.1 - 1.1e-23 83.5 0.7 2.9e-23 82.2 0.3 2.0 2 0 0 2 2 2 1 FAD binding domain ALO PF04030.14 KFM28484.1 - 1.3e-14 54.6 0.0 4e-06 26.8 0.0 2.4 2 1 0 2 2 2 2 D-arabinono-1,4-lactone oxidase OTU PF02338.19 KFM28485.1 - 8.5e-06 26.3 0.0 3e-05 24.5 0.0 1.9 1 1 0 1 1 1 1 OTU-like cysteine protease UIM PF02809.20 KFM28485.1 - 0.0067 16.3 3.8 0.0067 16.3 3.8 2.0 2 0 0 2 2 2 1 Ubiquitin interaction motif Ribosomal_L19e PF01280.20 KFM28486.1 - 1.1e-63 213.6 10.3 1.1e-63 213.6 10.3 1.5 2 0 0 2 2 2 1 Ribosomal protein L19e Pentapeptide_2 PF01469.18 KFM28489.1 - 0.073 13.0 12.6 0.11 12.4 12.6 1.2 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) PPDK_N PF01326.19 KFM28490.1 - 1.2e-22 80.6 0.0 5.5e-18 65.3 0.0 3.9 1 1 1 2 2 2 2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain CBM53 PF16760.5 KFM28490.1 - 0.11 13.1 0.0 2.6 8.7 0.0 2.5 2 0 0 2 2 2 0 Starch/carbohydrate-binding module (family 53) RRM_1 PF00076.22 KFM28492.1 - 3.1e-17 62.2 0.8 6.7e-09 35.5 0.3 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OTU PF02338.19 KFM28492.1 - 1.7e-05 25.3 0.0 5e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 OTU-like cysteine protease PHM7_cyt PF14703.6 KFM28492.1 - 0.0035 17.6 0.2 0.62 10.3 0.0 2.8 1 1 1 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter Nup35_RRM_2 PF14605.6 KFM28492.1 - 0.059 13.4 0.1 0.18 11.9 0.1 1.8 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif APG6_N PF17675.1 KFM28492.1 - 0.061 13.8 1.7 0.12 12.9 1.7 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region SVIP PF15811.5 KFM28492.1 - 0.062 13.8 1.8 0.17 12.4 1.8 1.7 1 0 0 1 1 1 0 Small VCP/p97-interacting protein OrfB_Zn_ribbon PF07282.11 KFM28492.1 - 0.16 11.9 0.4 0.6 10.1 0.4 2.0 1 0 0 1 1 1 0 Putative transposase DNA-binding domain ERM PF00769.19 KFM28492.1 - 4 7.2 5.8 7.2 6.4 5.8 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF3138 PF11336.8 KFM28492.1 - 8.7 4.8 7.5 14 4.2 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) RuBisCO_small PF00101.20 KFM28493.1 - 0.13 12.3 0.0 0.2 11.7 0.0 1.3 1 1 0 1 1 1 0 Ribulose bisphosphate carboxylase, small chain bZIP_1 PF00170.21 KFM28494.1 - 7.7e-06 25.9 5.6 1.8e-05 24.7 5.6 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFM28494.1 - 4.2e-05 23.5 5.3 0.00014 21.9 5.3 1.9 1 0 0 1 1 1 1 Basic region leucine zipper CCCAP PF15964.5 KFM28494.1 - 0.0015 16.9 2.6 0.0019 16.6 2.6 1.1 1 0 0 1 1 1 1 Centrosomal colon cancer autoantigen protein family DivIC PF04977.15 KFM28494.1 - 0.67 9.8 3.0 0.65 9.8 1.7 1.7 1 1 0 1 1 1 0 Septum formation initiator APG6_N PF17675.1 KFM28494.1 - 1.7 9.1 7.8 3 8.4 7.8 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region HAUS-augmin3 PF14932.6 KFM28494.1 - 4 6.9 8.0 5.9 6.4 8.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 MCM PF00493.23 KFM28495.1 - 1.6e-98 328.3 0.0 2.5e-98 327.6 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KFM28495.1 - 3.5e-37 127.1 0.6 5.6e-37 126.4 0.6 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_N PF14551.6 KFM28495.1 - 2.2e-17 63.5 0.1 5.1e-17 62.4 0.1 1.6 1 0 0 1 1 1 1 MCM N-terminal domain MCM6_C PF18263.1 KFM28495.1 - 2.5e-10 40.5 0.0 4.9e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 KFM28495.1 - 8.8e-10 38.9 0.5 2.1e-09 37.7 0.5 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 KFM28495.1 - 1.4e-08 34.4 0.0 2.4e-06 27.1 0.0 2.3 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KFM28495.1 - 0.00011 22.1 0.0 0.0004 20.3 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFM28495.1 - 0.0017 18.4 0.0 0.0032 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KFM28495.1 - 0.007 16.1 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_lid_2 PF17863.1 KFM28495.1 - 0.46 10.3 5.1 0.18 11.7 1.5 2.2 2 0 0 2 2 2 0 AAA lid domain Cyclin_N PF00134.23 KFM28496.1 - 9.5e-42 141.7 0.0 2.7e-41 140.3 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFM28496.1 - 6.6e-34 116.5 0.6 1.2e-33 115.7 0.4 1.5 2 0 0 2 2 2 1 Cyclin, C-terminal domain F-box-like PF12937.7 KFM28497.1 - 1.8e-06 27.7 0.1 3e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFM28497.1 - 5.1e-06 26.2 0.1 8.8e-06 25.5 0.1 1.3 1 0 0 1 1 1 1 F-box domain DNA_pol_E_B PF04042.16 KFM28498.1 - 6.3e-26 91.0 0.1 2.7e-20 72.6 0.0 2.3 1 1 1 2 2 2 2 DNA polymerase alpha/epsilon subunit B CcmE PF03100.15 KFM28498.1 - 0.0028 17.6 0.0 0.005 16.8 0.0 1.3 1 0 0 1 1 1 1 CcmE NUDIX PF00293.28 KFM28499.1 - 1.7e-21 76.6 0.0 2e-21 76.4 0.0 1.0 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KFM28499.1 - 0.0038 17.2 0.1 0.0053 16.7 0.1 1.5 1 1 0 1 1 1 1 NUDIX domain Acyl-CoA_dh_M PF02770.19 KFM28500.1 - 3.3e-17 62.5 0.0 5.3e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KFM28500.1 - 7.7e-15 55.4 1.4 1.5e-14 54.5 1.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KFM28500.1 - 0.0066 17.1 0.1 0.03 15.0 0.1 2.2 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Toxin_5 PF05294.13 KFM28500.1 - 0.17 12.3 3.8 0.57 10.6 3.8 1.8 1 0 0 1 1 1 0 Scorpion short toxin PSII_Pbs27 PF13326.6 KFM28502.1 - 2.7e-24 86.1 0.0 3e-24 85.9 0.0 1.0 1 0 0 1 1 1 1 Photosystem II Pbs27 YccV-like PF08755.11 KFM28503.1 - 2.3e-05 24.8 0.0 3.8e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like DUF1995 PF09353.10 KFM28504.1 - 5.1e-38 131.1 0.0 6.7e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) OrfB_Zn_ribbon PF07282.11 KFM28507.1 - 0.0032 17.4 6.5 0.02 14.8 6.5 2.3 1 1 0 1 1 1 1 Putative transposase DNA-binding domain CAP_N PF01213.19 KFM28507.1 - 0.11 12.0 0.6 0.2 11.1 0.6 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SKI PF01202.22 KFM28508.1 - 9.3e-07 29.1 0.0 4e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 Shikimate kinase AAA_33 PF13671.6 KFM28508.1 - 0.0003 21.0 0.0 0.00042 20.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain Peptidase_M28 PF04389.17 KFM28509.1 - 1.8e-27 96.3 0.0 2.9e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 cobW PF02492.19 KFM28510.1 - 2.2e-38 131.6 0.1 3e-38 131.2 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KFM28510.1 - 1.8e-19 69.5 0.6 2.8e-18 65.6 0.6 2.3 1 1 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 KFM28510.1 - 0.0079 16.1 0.3 3.7 7.4 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase TsaE PF02367.17 KFM28510.1 - 0.015 15.3 0.1 0.031 14.3 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 KFM28510.1 - 0.08 13.3 0.3 0.23 11.9 0.3 1.9 1 1 0 1 1 1 0 AAA ATPase domain MeaB PF03308.16 KFM28510.1 - 0.1 11.6 0.0 10 5.0 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA PF00004.29 KFM28510.1 - 0.14 12.6 0.0 0.63 10.5 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SpoU_methylase PF00588.19 KFM28511.1 - 1.5e-15 57.6 0.0 3.4e-07 30.5 0.0 2.2 1 1 1 2 2 2 2 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 KFM28511.1 - 1.5e-12 47.6 0.0 2.3e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding Sec23_trunk PF04811.15 KFM28512.1 - 2.1e-06 27.5 0.0 7.6e-06 25.7 0.0 1.9 2 1 1 3 3 3 1 Sec23/Sec24 trunk domain zf-Sec23_Sec24 PF04810.15 KFM28512.1 - 0.0012 18.8 1.8 0.0022 18.0 1.8 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger COX6A PF02046.15 KFM28513.1 - 3.7e-06 27.4 0.6 9.7e-06 26.0 0.6 1.7 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIa FTHFS PF01268.19 KFM28513.1 - 0.0013 17.0 0.0 0.0014 16.9 0.0 1.0 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase Na_H_Exchanger PF00999.21 KFM28516.1 - 2.2e-30 105.7 35.8 3.4e-30 105.1 35.8 1.3 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family ABC2_membrane PF01061.24 KFM28517.1 - 9.2e-75 250.6 69.3 2.4e-49 167.6 26.7 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KFM28517.1 - 3e-33 115.2 0.0 1e-16 61.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_assoc PF08370.11 KFM28517.1 - 1.1e-09 37.8 9.6 7.8e-07 28.8 0.0 3.5 3 0 0 3 3 2 2 Plant PDR ABC transporter associated AAA_21 PF13304.6 KFM28517.1 - 2.6e-06 27.5 0.0 1 9.1 0.0 3.2 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KFM28517.1 - 7.5e-06 25.6 1.1 0.023 14.3 0.3 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KFM28517.1 - 8.1e-06 25.5 1.5 0.031 14.0 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 KFM28517.1 - 1.3e-05 25.5 0.2 0.086 13.1 0.1 2.4 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KFM28517.1 - 0.00013 22.0 0.2 0.36 10.9 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 KFM28517.1 - 0.00017 22.1 0.1 0.61 10.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KFM28517.1 - 0.00024 21.5 0.1 0.72 10.2 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 KFM28517.1 - 0.00038 20.2 0.7 0.67 9.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KFM28517.1 - 0.00047 20.3 0.1 1.3 9.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KFM28517.1 - 0.00054 20.5 0.1 1.3 9.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KFM28517.1 - 0.00069 19.9 1.7 0.93 9.8 0.1 3.2 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 KFM28517.1 - 0.0025 18.2 0.1 1.9 8.9 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PDR_CDR PF06422.12 KFM28517.1 - 0.0027 17.6 0.6 0.0027 17.6 0.6 2.8 3 0 0 3 3 2 1 CDR ABC transporter RNA_helicase PF00910.22 KFM28517.1 - 0.008 16.6 0.1 3.8 7.9 0.0 2.5 2 0 0 2 2 2 1 RNA helicase RsgA_GTPase PF03193.16 KFM28517.1 - 0.01 15.8 1.8 0.053 13.4 0.4 2.4 2 0 0 2 2 2 0 RsgA GTPase Roc PF08477.13 KFM28517.1 - 0.019 15.1 0.2 5.8 7.2 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PRTase_2 PF15609.6 KFM28517.1 - 0.027 14.0 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosyl transferase NTPase_1 PF03266.15 KFM28517.1 - 0.031 14.2 3.5 3.6 7.5 0.0 3.3 3 0 0 3 3 3 0 NTPase AAA_24 PF13479.6 KFM28517.1 - 0.034 13.9 1.6 4.2 7.0 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_15 PF13175.6 KFM28517.1 - 0.048 13.4 0.0 14 5.2 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain ATPase_2 PF01637.18 KFM28517.1 - 0.049 13.5 0.0 0.24 11.3 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 KFM28517.1 - 0.054 13.8 1.8 0.19 12.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KFM28517.1 - 0.065 13.2 1.3 13 5.7 0.0 2.5 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 KFM28517.1 - 0.066 13.2 0.5 16 5.5 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 KFM28517.1 - 0.086 12.4 2.0 9.3 5.8 0.4 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 KFM28517.1 - 0.11 12.1 1.1 17 4.9 0.0 3.2 3 0 0 3 3 3 0 Ferrous iron transport protein B SMC_N PF02463.19 KFM28517.1 - 0.11 11.9 0.3 79 2.6 0.0 3.5 4 0 0 4 4 4 0 RecF/RecN/SMC N terminal domain PduV-EutP PF10662.9 KFM28517.1 - 0.11 12.2 0.6 3.4 7.4 0.2 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 KFM28517.1 - 0.15 12.1 0.3 2.9 7.9 0.0 2.3 2 0 0 2 2 2 0 Dynamin family ATP_bind_1 PF03029.17 KFM28517.1 - 0.19 11.5 0.5 2.4 7.9 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Xan_ur_permease PF00860.20 KFM28519.1 - 1.7e-27 96.2 32.5 1.1e-17 63.8 16.6 2.2 2 0 0 2 2 2 2 Permease family Toprim_4 PF13662.6 KFM28520.1 - 6.8e-18 64.9 0.0 1.6e-17 63.7 0.0 1.7 1 0 0 1 1 1 1 Toprim domain AAA_25 PF13481.6 KFM28520.1 - 1.6e-07 31.1 0.0 1.3e-06 28.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain Toprim PF01751.22 KFM28520.1 - 2.5e-06 27.6 0.0 8.7e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 Toprim domain Toprim_2 PF13155.6 KFM28520.1 - 1.4e-05 25.4 0.1 6.5e-05 23.3 0.0 2.2 2 1 0 2 2 2 1 Toprim-like DnaB_C PF03796.15 KFM28520.1 - 8.6e-05 22.0 0.0 0.012 15.0 0.0 2.2 2 0 0 2 2 2 2 DnaB-like helicase C terminal domain FtsK_SpoIIIE PF01580.18 KFM28520.1 - 0.011 15.1 0.0 0.029 13.7 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_29 PF13555.6 KFM28520.1 - 0.17 11.6 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Toprim_3 PF13362.6 KFM28520.1 - 0.2 12.0 3.6 0.39 11.1 0.2 3.0 3 0 0 3 3 3 0 Toprim domain Cpn60_TCP1 PF00118.24 KFM28521.1 - 5.4e-154 513.4 9.1 6.2e-154 513.3 9.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CLP_protease PF00574.23 KFM28522.1 - 2.3e-39 135.1 0.0 4.7e-39 134.2 0.0 1.4 1 1 0 1 1 1 1 Clp protease Peptidase_S49 PF01343.18 KFM28522.1 - 0.067 13.1 0.2 0.25 11.3 0.1 1.8 2 0 0 2 2 2 0 Peptidase family S49 ATP_bind_3 PF01171.20 KFM28523.1 - 1.8e-15 57.2 0.0 3.1e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 KFM28523.1 - 2e-07 30.4 0.9 2e-07 30.4 0.9 3.4 3 0 0 3 3 3 1 Zinc-ribbon tRNA_Me_trans PF03054.16 KFM28523.1 - 0.0024 16.7 0.0 0.0033 16.3 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase PAPS_reduct PF01507.19 KFM28523.1 - 0.044 13.8 0.0 0.058 13.4 0.0 1.2 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family E1-E2_ATPase PF00122.20 KFM28524.1 - 4.7e-51 172.9 1.5 5.7e-51 172.6 0.3 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KFM28524.1 - 3.3e-38 132.1 14.7 9.2e-37 127.4 14.7 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFM28524.1 - 3.2e-05 24.4 3.5 0.00027 21.4 1.1 3.0 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KFM28524.1 - 8.8e-05 22.4 0.8 0.00098 18.9 1.0 2.0 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Glyoxalase PF00903.25 KFM28525.1 - 3.7e-08 33.6 0.0 0.0073 16.5 0.0 2.8 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KFM28525.1 - 3.5e-05 24.0 0.1 0.0044 17.3 0.0 3.2 3 1 0 3 3 3 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KFM28525.1 - 0.023 14.8 0.1 0.97 9.5 0.0 3.2 2 2 1 3 3 3 0 Glyoxalase-like domain SET PF00856.28 KFM28527.1 - 1.8e-06 28.4 0.0 2.7e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 SET domain NinF PF05810.12 KFM28527.1 - 0.16 11.9 2.8 1.1 9.2 0.0 2.9 3 0 0 3 3 3 0 NinF protein Glyco_transf_5 PF08323.11 KFM28528.1 - 3.6e-22 79.2 0.0 7.7e-22 78.2 0.0 1.6 2 0 0 2 2 2 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KFM28528.1 - 5.7e-05 22.7 0.0 8.6e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KFM28528.1 - 0.0023 18.3 0.1 0.0039 17.6 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KFM28528.1 - 0.016 15.7 1.6 0.016 15.7 1.6 2.5 1 1 1 2 2 2 0 Glycosyl transferase 4-like domain Porin_3 PF01459.22 KFM28529.1 - 2.8e-58 197.5 0.1 3.6e-58 197.2 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic porin MDM10 PF12519.8 KFM28529.1 - 3.3e-06 26.3 0.3 4.8e-06 25.7 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial distribution and morphology protein 10 SAND PF01342.21 KFM28529.1 - 0.00015 21.4 0.0 0.0003 20.4 0.0 1.4 1 0 0 1 1 1 1 SAND domain UQ_con PF00179.26 KFM28530.1 - 6.1e-51 171.7 0.0 7e-51 171.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme FtsJ PF01728.19 KFM28532.1 - 4.8e-14 52.9 0.0 5.3e-14 52.7 0.0 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase Peptidase_M3 PF01432.20 KFM28533.1 - 1.7e-125 419.9 0.0 2.6e-125 419.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Anti-TRAP PF15777.5 KFM28533.1 - 0.011 15.7 1.2 0.027 14.5 1.2 1.5 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein Peptidase_M50B PF13398.6 KFM28533.1 - 0.027 14.1 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase M50B-like Prim_Zn_Ribbon PF08273.12 KFM28533.1 - 2.8 8.3 5.1 1.1 9.6 0.1 2.6 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase AAA_2 PF07724.14 KFM28534.1 - 1e-56 191.8 0.1 3.1e-55 186.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Clp_N PF02861.20 KFM28534.1 - 3.1e-38 129.7 3.8 1.8e-18 66.4 0.1 3.0 3 0 0 3 3 2 2 Clp amino terminal domain, pathogenicity island component AAA_lid_9 PF17871.1 KFM28534.1 - 1.1e-33 115.2 0.3 2.4e-33 114.2 0.3 1.6 1 0 0 1 1 1 1 AAA lid domain AAA PF00004.29 KFM28534.1 - 2.4e-23 83.0 0.3 2.1e-13 50.8 0.0 3.1 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KFM28534.1 - 6.5e-23 80.6 0.2 6.5e-23 80.6 0.2 2.5 3 0 0 3 3 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KFM28534.1 - 2e-18 66.7 0.1 2.1e-11 43.9 0.0 3.2 2 1 1 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFM28534.1 - 1e-11 45.5 1.4 1.6e-05 25.4 0.1 4.1 3 1 1 4 4 4 2 AAA ATPase domain Sigma54_activat PF00158.26 KFM28534.1 - 1.9e-08 34.2 0.0 1.4e-05 24.9 0.0 2.7 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.6 KFM28534.1 - 2e-07 31.4 4.6 0.012 15.9 0.3 5.3 4 2 0 4 4 2 2 AAA domain TniB PF05621.11 KFM28534.1 - 2.1e-06 27.3 0.0 0.0013 18.2 0.1 4.0 3 1 0 3 3 3 1 Bacterial TniB protein UVR PF02151.19 KFM28534.1 - 4.1e-06 26.4 3.7 4.1e-06 26.4 3.7 1.9 2 0 0 2 2 1 1 UvrB/uvrC motif AAA_14 PF13173.6 KFM28534.1 - 6.4e-06 26.2 0.0 0.19 11.8 0.0 3.3 3 0 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 KFM28534.1 - 1e-05 25.4 0.0 0.044 13.5 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 KFM28534.1 - 1.3e-05 25.8 0.1 0.16 12.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KFM28534.1 - 7.9e-05 23.0 0.1 0.55 10.6 0.0 2.8 3 0 0 3 3 2 2 RNA helicase NACHT PF05729.12 KFM28534.1 - 0.00014 21.8 0.1 0.035 14.0 0.0 2.9 2 1 0 2 2 2 1 NACHT domain Mg_chelatase PF01078.21 KFM28534.1 - 0.00019 20.9 0.2 2 7.8 0.0 3.4 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 KFM28534.1 - 0.00027 20.9 1.0 1.5 8.7 0.0 3.9 4 0 0 4 4 4 1 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 KFM28534.1 - 0.00048 19.5 0.0 0.11 11.8 0.0 3.0 2 0 0 2 2 2 1 Zeta toxin AAA_24 PF13479.6 KFM28534.1 - 0.00072 19.3 0.0 1.3 8.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 KFM28534.1 - 0.00098 18.9 0.9 11 5.7 0.0 4.5 4 1 0 4 4 4 0 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 KFM28534.1 - 0.00099 18.7 0.1 0.072 12.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 KFM28534.1 - 0.0011 19.2 0.0 1.8 8.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KFM28534.1 - 0.0012 18.8 0.0 0.77 9.7 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_3 PF07726.11 KFM28534.1 - 0.0043 16.9 0.1 0.79 9.6 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 KFM28534.1 - 0.0046 17.0 0.0 5.9 6.8 0.0 3.4 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit TsaE PF02367.17 KFM28534.1 - 0.0047 16.9 0.0 1.7 8.7 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KFM28534.1 - 0.0048 16.4 0.0 2.6 7.5 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region DNA_pol3_delta2 PF13177.6 KFM28534.1 - 0.0081 16.0 0.0 2.9 7.7 0.0 3.0 3 0 0 3 3 3 1 DNA polymerase III, delta subunit AAA_28 PF13521.6 KFM28534.1 - 0.016 15.4 2.2 5.9 7.1 0.0 3.3 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 KFM28534.1 - 0.021 15.3 0.0 3.1 8.3 0.0 2.7 2 1 0 2 2 2 0 ABC transporter AAA_10 PF12846.7 KFM28534.1 - 0.037 13.0 0.2 2.3 7.1 0.0 2.6 3 0 0 3 3 3 0 AAA-like domain Roc PF08477.13 KFM28534.1 - 0.074 13.3 0.0 13 6.0 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF2283 PF10049.9 KFM28534.1 - 1.7 8.9 3.5 32 4.8 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2283) Nup_retrotrp_bd PF10599.9 KFM28537.1 - 0.01 16.5 12.2 0.51 11.0 12.2 2.1 1 1 0 1 1 1 0 Retro-transposon transporting motif SF3b10 PF07189.11 KFM28538.1 - 1.7e-36 124.2 0.0 1.9e-36 124.0 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) PFK PF00365.20 KFM28539.1 - 1.7e-52 178.5 0.0 2.1e-52 178.2 0.0 1.1 1 0 0 1 1 1 1 Phosphofructokinase Phosphorylase PF00343.20 KFM28540.1 - 0 1023.8 0.0 0 1023.4 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate phosphorylase ACT PF01842.25 KFM28540.1 - 8.3e-06 25.5 0.0 4.3e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 ACT domain RDV-p3 PF09231.10 KFM28540.1 - 0.21 9.3 0.0 0.34 8.6 0.0 1.2 1 0 0 1 1 1 0 Rice dwarf virus p3 YEATS PF03366.16 KFM28541.1 - 4.9e-29 100.1 0.3 7.5e-29 99.5 0.3 1.3 1 0 0 1 1 1 1 YEATS family CBM46 PF18448.1 KFM28541.1 - 0.14 12.5 0.2 4 7.8 0.0 2.5 2 1 1 3 3 3 0 Carbohydrate binding domain CutA1 PF03091.15 KFM28542.1 - 2.1e-36 123.7 0.0 2.4e-36 123.5 0.0 1.0 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein RAD51_interact PF15696.5 KFM28542.1 - 0.12 12.4 0.4 0.21 11.7 0.4 1.4 1 0 0 1 1 1 0 RAD51 interacting motif Acetyltransf_CG PF14542.6 KFM28542.1 - 0.15 12.2 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Fasciclin PF02469.22 KFM28543.1 - 0.04 14.1 0.0 0.051 13.8 0.0 1.2 1 0 0 1 1 1 0 Fasciclin domain RecQ_Zn_bind PF16124.5 KFM28544.1 - 4.5e-17 62.5 3.7 1e-16 61.4 3.7 1.7 1 0 0 1 1 1 1 RecQ zinc-binding Helicase_C PF00271.31 KFM28544.1 - 6.8e-16 58.6 0.0 5.1e-15 55.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFM28544.1 - 1.9e-11 44.0 0.0 4.6e-10 39.5 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase RQC PF09382.10 KFM28544.1 - 1.9e-06 27.6 0.0 5.4e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 RQC domain SNF2_N PF00176.23 KFM28544.1 - 0.025 13.3 0.0 0.034 12.9 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain ResIII PF04851.15 KFM28544.1 - 0.042 13.8 0.0 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit MutS_V PF00488.21 KFM28545.1 - 2.5e-29 102.6 0.0 3.9e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 MutS domain V Histone PF00125.24 KFM28545.1 - 8.7e-18 64.9 0.0 1.4e-17 64.3 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KFM28545.1 - 6.5e-13 48.2 0.9 1.3e-12 47.2 0.9 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KFM28545.1 - 0.00015 22.0 0.0 0.00041 20.6 0.0 1.8 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Vps54 PF07928.12 KFM28545.1 - 0.012 16.1 0.1 6.4 7.2 0.1 2.3 2 0 0 2 2 2 0 Vps54-like protein MutS_III PF05192.18 KFM28546.1 - 2.7e-31 109.3 0.0 4.5e-31 108.6 0.0 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KFM28546.1 - 2.1e-25 89.1 0.0 3.3e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 MutS domain I MutS_V PF00488.21 KFM28546.1 - 1.5e-14 54.5 0.2 2.5e-14 53.8 0.2 1.4 1 0 0 1 1 1 1 MutS domain V MutS_II PF05188.17 KFM28546.1 - 7.7e-05 23.0 0.0 0.00017 21.8 0.0 1.6 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 KFM28546.1 - 0.0076 16.6 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 MutS family domain IV CoaE PF01121.20 KFM28547.1 - 1.7e-32 112.5 0.0 2e-32 112.3 0.0 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.6 KFM28547.1 - 0.076 13.4 0.0 37 4.7 0.0 3.0 2 1 1 3 3 3 0 AAA domain Thiolase_N PF00108.23 KFM28548.1 - 2.9e-84 282.5 0.5 6e-84 281.5 0.5 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFM28548.1 - 1.4e-40 137.8 0.8 1.5e-38 131.2 0.2 2.7 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KFM28548.1 - 8.5e-06 25.5 4.3 0.00059 19.5 2.8 2.8 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 KFM28548.1 - 0.029 13.1 0.1 0.045 12.5 0.1 1.2 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) Ketoacyl-synt_C PF02801.22 KFM28548.1 - 0.033 14.2 0.4 6.3 6.8 0.0 3.4 3 0 0 3 3 3 0 Beta-ketoacyl synthase, C-terminal domain ACP_syn_III PF08545.10 KFM28548.1 - 1.1 9.1 5.0 1.8 8.5 0.4 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III zf-CCCH PF00642.24 KFM28550.1 - 2.5e-18 65.5 25.5 1.3e-07 31.4 0.9 3.4 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KFM28550.1 - 5.2e-17 61.2 25.3 3.8e-08 33.0 1.1 3.5 3 0 0 3 3 3 3 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KFM28550.1 - 1.9e-16 59.5 31.4 1.6e-07 31.1 4.0 3.4 3 0 0 3 3 3 3 Zinc finger domain Torus PF16131.5 KFM28550.1 - 1.2e-11 45.3 14.3 0.00018 22.2 1.7 3.4 2 1 1 3 3 3 3 Torus domain zf-RING_5 PF14634.6 KFM28550.1 - 5.5e-09 35.9 1.9 1.9e-08 34.1 1.9 2.0 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KFM28550.1 - 2.5e-08 33.6 1.7 5.6e-08 32.5 1.0 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM28550.1 - 9.1e-08 32.3 2.6 9.1e-08 32.3 2.6 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 KFM28550.1 - 1.9e-06 27.6 2.9 7.6e-06 25.7 2.9 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH_2 PF14608.6 KFM28550.1 - 5.4e-06 26.7 22.5 0.016 15.6 3.9 3.5 3 0 0 3 3 3 3 RNA-binding, Nab2-type zinc finger zf-RING_UBOX PF13445.6 KFM28550.1 - 2.3e-05 24.3 1.9 0.00035 20.5 0.1 2.8 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KFM28550.1 - 4.4e-05 23.2 0.4 4.4e-05 23.2 0.4 2.3 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KFM28550.1 - 0.00015 21.8 5.0 0.00079 19.5 3.2 3.1 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-CCCH_3 PF15663.5 KFM28550.1 - 0.0012 19.0 4.4 0.0012 19.0 4.4 2.4 2 0 0 2 2 2 1 Zinc-finger containing family zf-rbx1 PF12678.7 KFM28550.1 - 0.0016 18.7 3.8 0.0016 18.7 3.8 2.6 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KFM28550.1 - 0.0024 17.6 1.2 0.0024 17.6 1.2 2.5 3 0 0 3 3 2 1 RING-like zinc finger zf-ANAPC11 PF12861.7 KFM28550.1 - 0.0087 16.1 0.2 0.0087 16.1 0.2 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_RING PF05883.11 KFM28550.1 - 0.011 15.7 0.4 0.02 14.9 0.4 1.4 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-C3HC4_2 PF13923.6 KFM28550.1 - 0.048 13.5 10.1 2 8.3 10.4 3.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF962 PF06127.11 KFM28551.1 - 3.2e-32 110.5 0.6 3.6e-32 110.3 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF962) SLAC1 PF03595.17 KFM28552.1 - 1.1e-20 74.2 51.4 1.7e-12 47.3 37.6 2.0 1 1 1 2 2 2 2 Voltage-dependent anion channel VRR_NUC PF08774.11 KFM28553.1 - 2.9e-21 75.6 0.0 6e-21 74.5 0.0 1.5 1 0 0 1 1 1 1 VRR-NUC domain HIRAN PF08797.11 KFM28553.1 - 7.8e-10 38.6 0.0 1.8e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain DUF4131 PF13567.6 KFM28553.1 - 0.088 12.5 0.1 0.088 12.5 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Cytochrom_C_2 PF01322.20 KFM28553.1 - 0.21 12.5 3.6 0.6 11.0 0.1 2.6 2 0 0 2 2 2 0 Cytochrome C' MOR2-PAG1_mid PF14228.6 KFM28554.1 - 8.2e-126 421.2 2.1 3e-48 164.3 1.2 3.3 1 1 2 3 3 3 3 Cell morphogenesis central region MOR2-PAG1_N PF14222.6 KFM28554.1 - 2.9e-54 185.0 0.0 1.2e-53 182.9 0.0 2.1 3 1 0 3 3 3 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 KFM28554.1 - 8.7e-11 42.2 0.2 4.5e-06 26.7 0.0 4.1 4 0 0 4 4 4 2 Cell morphogenesis C-terminal MMS19_N PF14500.6 KFM28554.1 - 0.015 14.9 0.4 0.26 10.8 0.1 2.8 2 0 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II APC_r PF05923.12 KFM28554.1 - 0.058 13.1 0.1 0.14 11.9 0.1 1.7 1 0 0 1 1 1 0 APC repeat ATP-grasp_2 PF08442.10 KFM28556.1 - 2.8e-63 213.1 0.2 4e-63 212.6 0.2 1.2 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 KFM28556.1 - 1.4e-27 96.4 1.1 3.6e-27 95.1 1.1 1.7 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 KFM28556.1 - 4.5e-06 26.3 0.4 1.3e-05 24.7 0.4 1.8 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KFM28556.1 - 0.024 14.4 0.2 0.071 12.9 0.2 1.7 1 1 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain EFhand_Ca_insen PF08726.10 KFM28556.1 - 0.13 12.4 0.1 34 4.6 0.0 2.9 3 0 0 3 3 3 0 Ca2+ insensitive EF hand FbpA PF05833.11 KFM28556.1 - 0.22 10.3 0.0 0.33 9.6 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) AhpC-TSA PF00578.21 KFM28557.1 - 5.4e-40 136.2 0.0 4.9e-36 123.4 0.0 2.7 3 0 0 3 3 3 2 AhpC/TSA family Thioredoxin PF00085.20 KFM28557.1 - 6.1e-22 77.6 0.2 1.2e-21 76.7 0.2 1.5 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 KFM28557.1 - 1.6e-17 63.6 0.0 3e-12 46.5 0.0 2.3 2 0 0 2 2 2 2 Redoxin 1-cysPrx_C PF10417.9 KFM28557.1 - 2.9e-11 43.0 0.0 7e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Thioredoxin_2 PF13098.6 KFM28557.1 - 7e-05 23.2 0.1 0.00038 20.9 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KFM28557.1 - 0.00029 21.1 0.0 0.00089 19.5 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 KFM28557.1 - 0.0022 17.8 0.0 0.004 16.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin His_Phos_2 PF00328.22 KFM28558.1 - 1.1e-22 81.0 0.0 3e-12 46.6 0.0 2.5 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) ABC2_membrane_3 PF12698.7 KFM28559.1 - 3e-20 72.6 11.9 4.4e-20 72.1 11.9 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 KFM28559.1 - 6e-10 39.8 0.0 1.1e-09 38.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KFM28559.1 - 7.9e-10 39.0 0.0 1.2e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane PF01061.24 KFM28559.1 - 3.1e-05 23.5 12.3 3.1e-05 23.5 12.3 2.3 2 0 0 2 2 2 1 ABC-2 type transporter ScsC_N PF18312.1 KFM28559.1 - 0.058 13.2 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 Copper resistance protein ScsC N-terminal domain ABC2_membrane_2 PF12679.7 KFM28559.1 - 0.1 11.8 10.5 0.21 10.9 10.5 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2569 PF10754.9 KFM28559.1 - 0.3 11.5 5.6 0.74 10.2 5.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) Aminotran_1_2 PF00155.21 KFM28560.1 - 2.1e-86 290.4 0.0 2.6e-86 290.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II TetR_C_28 PF17937.1 KFM28560.1 - 0.0045 17.4 0.1 0.91 10.0 0.1 2.8 2 0 0 2 2 2 2 Tetracyclin repressor-like, C-terminal domain POPLD PF08170.12 KFM28562.1 - 6.1e-15 55.3 0.1 1.2e-14 54.4 0.1 1.4 1 0 0 1 1 1 1 POPLD (NUC188) domain POP1 PF06978.11 KFM28562.1 - 4.1e-14 53.1 4.6 4.9e-09 36.5 0.0 2.3 2 0 0 2 2 2 2 Ribonucleases P/MRP protein subunit POP1 Fe_hyd_lg_C PF02906.14 KFM28565.1 - 1.3e-51 175.6 0.0 4.2e-48 164.1 0.0 2.1 1 1 1 2 2 2 2 Iron only hydrogenase large subunit, C-terminal domain AIG2_2 PF13772.6 KFM28566.1 - 1.2e-08 35.2 0.0 2e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family GGACT PF06094.12 KFM28566.1 - 0.0023 18.5 0.1 0.017 15.8 0.1 2.4 2 1 0 2 2 2 1 Gamma-glutamyl cyclotransferase, AIG2-like PRA-PH PF01503.17 KFM28566.1 - 0.012 16.1 0.0 0.029 14.8 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase Asp PF00026.23 KFM28568.1 - 4.8e-109 364.6 0.0 7.5e-109 364.0 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KFM28568.1 - 1.2e-13 51.7 0.8 8.7e-12 45.6 0.0 3.2 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal SapB_1 PF05184.15 KFM28568.1 - 5.6e-10 39.0 1.2 1.2e-09 38.0 1.2 1.6 1 0 0 1 1 1 1 Saposin-like type B, region 1 SapB_2 PF03489.17 KFM28568.1 - 1.1e-07 31.9 2.4 1.1e-07 31.9 2.4 2.0 2 0 0 2 2 2 1 Saposin-like type B, region 2 Asp_protease_2 PF13650.6 KFM28568.1 - 0.014 16.0 0.0 7.8 7.2 0.0 3.8 4 0 0 4 4 4 0 Aspartyl protease TAXi_C PF14541.6 KFM28568.1 - 0.019 14.7 0.0 0.044 13.5 0.0 1.6 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal PsbP PF01789.16 KFM28569.1 - 1.5e-21 77.2 0.0 1.7e-21 77.0 0.0 1.1 1 0 0 1 1 1 1 PsbP RRM_1 PF00076.22 KFM28570.1 - 1.7e-08 34.2 0.0 3.5e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Septin PF00735.18 KFM28571.1 - 6.6e-27 94.5 0.0 1.4e-14 54.1 0.0 2.2 1 1 0 2 2 2 2 Septin AAA_22 PF13401.6 KFM28571.1 - 0.0012 19.1 0.0 0.003 17.8 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.6 KFM28571.1 - 0.0014 18.4 0.1 0.0035 17.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFM28571.1 - 0.0014 19.0 0.6 0.0031 17.9 0.0 1.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 KFM28571.1 - 0.0061 16.3 0.6 0.037 13.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain CSN5_C PF18323.1 KFM28571.1 - 0.011 16.7 1.5 0.02 15.8 1.5 1.4 1 0 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain NACHT PF05729.12 KFM28571.1 - 0.012 15.6 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 KFM28571.1 - 0.015 14.8 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Alanine_zipper PF11839.8 KFM28571.1 - 0.029 14.7 6.0 0.055 13.8 6.0 1.5 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein AAA_25 PF13481.6 KFM28571.1 - 0.03 13.9 0.1 0.091 12.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain Roc PF08477.13 KFM28571.1 - 0.032 14.5 0.0 0.06 13.6 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Pox_A32 PF04665.12 KFM28571.1 - 0.04 13.4 0.0 0.067 12.6 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein MMR_HSR1 PF01926.23 KFM28571.1 - 0.042 13.9 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase YtxH PF12732.7 KFM28571.1 - 0.059 13.9 0.9 0.13 12.8 0.9 1.5 1 0 0 1 1 1 0 YtxH-like protein TsaE PF02367.17 KFM28571.1 - 0.08 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KFM28571.1 - 0.089 13.2 0.0 0.16 12.4 0.0 1.5 1 1 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 KFM28571.1 - 0.12 12.5 2.7 0.3 11.2 0.0 2.8 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KFM28571.1 - 0.16 11.9 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 NTPase ATP_bind_1 PF03029.17 KFM28571.1 - 0.16 11.7 0.1 0.33 10.7 0.0 1.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Sigma54_activat PF00158.26 KFM28571.1 - 0.17 11.6 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain G-alpha PF00503.20 KFM28571.1 - 0.25 10.5 0.0 0.41 9.8 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit DUF883 PF05957.13 KFM28571.1 - 1.5 9.4 7.8 3.7 8.2 7.8 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) GHMP_kinases_N PF00288.26 KFM28572.1 - 7.6e-12 45.3 4.9 7.6e-12 45.3 4.9 3.0 3 0 0 3 3 3 1 GHMP kinases N terminal domain GalKase_gal_bdg PF10509.9 KFM28572.1 - 9.9e-05 21.8 0.0 0.0005 19.6 0.0 2.2 2 0 0 2 2 2 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 KFM28572.1 - 0.0037 17.6 0.5 0.0037 17.6 0.5 2.3 2 0 0 2 2 2 1 GHMP kinases C terminal Phosducin PF02114.16 KFM28573.1 - 4e-07 29.3 0.0 5e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 KFM28573.1 - 2.9e-05 24.0 0.0 4.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin TatD_DNase PF01026.21 KFM28574.1 - 1.1e-47 162.6 0.0 1.2e-47 162.4 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase DUF2301 PF10063.9 KFM28574.1 - 0.19 12.1 0.0 18 5.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized integral membrane protein (DUF2301) DUF1543 PF07566.12 KFM28576.1 - 4.9 7.0 9.1 1.1 9.0 0.2 3.1 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1543) Ribosomal_S5 PF00333.20 KFM28576.1 - 5.6 7.0 6.8 1.9 8.6 0.4 2.6 2 0 0 2 2 2 0 Ribosomal protein S5, N-terminal domain Peptidase_S28 PF05577.12 KFM28577.1 - 8.6e-61 206.0 0.0 1.2e-60 205.6 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 KFM28577.1 - 0.00014 20.6 0.0 0.00019 20.3 0.0 1.1 1 0 0 1 1 1 1 PS-10 peptidase S37 Hydrolase_4 PF12146.8 KFM28577.1 - 0.00035 19.9 0.0 0.00058 19.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFM28577.1 - 0.002 17.8 0.0 0.0031 17.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFM28577.1 - 0.0024 18.5 3.2 0.0038 17.9 3.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KFM28577.1 - 0.021 14.3 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family NIF PF03031.18 KFM28581.1 - 6.6e-35 120.2 0.0 7.7e-35 120.0 0.0 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase zf-CCCH PF00642.24 KFM28582.1 - 1.7e-10 40.5 19.1 0.0048 16.8 1.4 4.4 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFM28582.1 - 5.5e-08 32.6 21.1 0.0028 17.7 3.4 4.8 4 1 0 4 4 4 3 Zinc finger domain Torus PF16131.5 KFM28582.1 - 1.1e-06 29.3 17.8 0.039 14.7 0.8 4.0 1 1 3 4 4 4 3 Torus domain zf-CCCH_3 PF15663.5 KFM28582.1 - 8.6e-05 22.7 5.8 0.021 15.1 0.5 2.3 1 1 1 2 2 2 2 Zinc-finger containing family zf-C3H1 PF10650.9 KFM28582.1 - 0.012 15.3 1.3 4.1 7.2 0.0 3.1 3 0 0 3 3 3 0 Putative zinc-finger domain zf-CCCH_4 PF18044.1 KFM28582.1 - 0.039 13.8 0.7 0.039 13.8 0.7 4.5 4 0 0 4 4 4 0 CCCH-type zinc finger AWS PF17907.1 KFM28582.1 - 2.6 8.2 0.0 2.6 8.2 0.0 3.5 4 0 0 4 4 4 0 AWS domain DnaJ PF00226.31 KFM28584.1 - 1.5e-07 31.4 0.0 2.2e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain NAD_kinase PF01513.21 KFM28585.1 - 4.7e-54 183.6 0.0 7.8e-54 182.8 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KFM28585.1 - 0.01 15.4 1.0 0.023 14.3 0.1 2.0 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain PspA_IM30 PF04012.12 KFM28585.1 - 0.32 10.5 5.7 0.58 9.7 5.7 1.3 1 0 0 1 1 1 0 PspA/IM30 family Metallophos_2 PF12850.7 KFM28586.1 - 4.9e-17 62.6 0.1 6.7e-17 62.2 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KFM28586.1 - 0.0018 18.8 2.1 0.39 11.2 0.5 2.8 2 1 1 3 3 3 2 Calcineurin-like phosphoesterase DUF3224 PF11528.8 KFM28586.1 - 0.026 14.3 0.0 0.043 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3224) RabGAP-TBC PF00566.18 KFM28587.1 - 1.9e-26 93.1 0.0 2.4e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RabGAP-TBC PF00566.18 KFM28588.1 - 1.9e-06 27.7 0.0 9.5e-06 25.4 0.0 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain SOG2 PF10428.9 KFM28588.1 - 1.9 7.6 6.9 3.3 6.8 6.9 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein SET PF00856.28 KFM28589.1 - 5.2e-10 40.0 0.0 1.6e-09 38.4 0.0 1.8 1 1 0 1 1 1 1 SET domain DUF1664 PF07889.12 KFM28590.1 - 0.0031 17.5 5.3 0.0066 16.5 0.3 3.0 1 1 2 3 3 3 1 Protein of unknown function (DUF1664) ATG16 PF08614.11 KFM28590.1 - 0.019 15.2 46.7 2.4 8.4 11.0 3.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Sec20 PF03908.13 KFM28590.1 - 0.032 14.2 3.3 1.7 8.6 0.5 2.6 2 1 0 2 2 2 0 Sec20 Spc7 PF08317.11 KFM28590.1 - 0.038 12.9 34.8 0.13 11.1 17.8 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein Sec2p PF06428.11 KFM28590.1 - 0.2 11.7 18.4 0.058 13.4 2.6 4.5 4 1 0 4 4 4 0 GDP/GTP exchange factor Sec2p DUF948 PF06103.11 KFM28590.1 - 0.61 10.4 8.1 4.4 7.6 0.3 3.4 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Jnk-SapK_ap_N PF09744.9 KFM28590.1 - 0.95 9.7 33.7 0.28 11.4 8.6 3.2 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 MIS13 PF08202.11 KFM28590.1 - 1.7 7.9 9.8 0.2 10.9 2.3 2.2 1 1 1 2 2 2 0 Mis12-Mtw1 protein family AIP3 PF03915.13 KFM28590.1 - 8.2 5.4 15.1 5.8 5.9 4.7 2.1 1 1 1 2 2 2 0 Actin interacting protein 3 MPC PF03650.13 KFM28591.1 - 1.2e-36 125.2 0.5 1.3e-36 125.1 0.5 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Peptidase_C26 PF07722.13 KFM28592.1 - 1.1e-17 64.6 0.0 6.8e-17 61.9 0.0 2.0 1 1 0 1 1 1 1 Peptidase C26 GATase PF00117.28 KFM28592.1 - 2.7e-08 33.8 0.0 5.2e-08 32.9 0.0 1.4 1 1 0 1 1 1 1 Glutamine amidotransferase class-I ABC1 PF03109.16 KFM28593.1 - 2.4e-32 111.6 0.0 4.5e-32 110.7 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 KFM28593.1 - 9e-05 22.0 0.0 0.006 16.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 KFM28593.1 - 0.00051 20.0 0.5 0.00051 20.0 0.5 3.4 2 2 1 3 3 3 1 Phosphotransferase enzyme family Ovate PF04844.13 KFM28593.1 - 0.046 13.7 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Transcriptional repressor, ovate WaaY PF06176.11 KFM28593.1 - 0.057 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) WD40 PF00400.32 KFM28594.1 - 1.5e-12 47.7 15.2 0.08 13.8 0.0 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat PQQ_3 PF13570.6 KFM28594.1 - 1.2e-05 25.7 2.7 1.3 9.7 0.3 4.4 4 0 0 4 4 4 2 PQQ-like domain Aconitase PF00330.20 KFM28595.1 - 1.4e-145 485.8 0.0 1.8e-145 485.5 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KFM28595.1 - 6.3e-44 149.5 0.1 1.7e-43 148.1 0.0 1.8 2 0 0 2 2 2 1 Aconitase C-terminal domain DUF521 PF04412.13 KFM28595.1 - 0.11 11.2 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Epimerase PF01370.21 KFM28596.1 - 9.1e-08 31.9 0.0 1.4e-05 24.7 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KFM28596.1 - 0.00074 18.7 0.0 0.0065 15.6 0.0 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain NmrA PF05368.13 KFM28596.1 - 0.0023 17.5 0.0 0.02 14.4 0.0 2.3 3 0 0 3 3 3 1 NmrA-like family FolB PF02152.18 KFM28597.1 - 6.6e-16 58.8 0.0 8.2e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Dihydroneopterin aldolase Med25_VWA PF11265.8 KFM28598.1 - 3e-05 23.9 0.0 0.00017 21.5 0.0 1.9 1 1 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A PCNA_C PF02747.15 KFM28599.1 - 5.2e-53 178.6 0.0 1.1e-52 177.6 0.0 1.5 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.18 KFM28599.1 - 4e-46 155.9 0.1 7.7e-46 154.9 0.1 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad9 PF04139.13 KFM28599.1 - 6.7e-06 25.7 0.0 9e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 KFM28599.1 - 2.6e-05 23.4 0.2 0.00017 20.8 0.2 1.9 1 1 1 2 2 2 1 Repair protein Rad1/Rec1/Rad17 MMR_HSR1 PF01926.23 KFM28600.1 - 9.9e-10 38.5 0.0 4.1e-09 36.5 0.0 2.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KFM28600.1 - 2.7e-07 30.8 0.1 0.00041 20.5 0.0 2.9 2 0 0 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 KFM28600.1 - 6e-06 26.3 0.0 1.3e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase cobW PF02492.19 KFM28600.1 - 0.0046 16.6 0.0 0.013 15.0 0.0 1.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 KFM28600.1 - 0.011 15.2 0.1 0.1 12.2 0.1 2.2 2 1 0 2 2 2 0 Ferrous iron transport protein B GTP_EFTU PF00009.27 KFM28600.1 - 0.022 14.3 0.0 0.63 9.5 0.0 2.6 3 1 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KFM28600.1 - 0.23 11.8 0.9 2.2 8.7 0.3 2.3 2 0 0 2 2 2 0 AAA ATPase domain Mre11_DNA_bind PF04152.14 KFM28601.1 - 4.5e-41 141.0 0.0 7.7e-41 140.2 0.0 1.4 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 KFM28601.1 - 2.5e-14 54.3 0.3 4.3e-14 53.5 0.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_19 PF14559.6 KFM28601.1 - 1.4e-07 31.9 10.8 0.00055 20.4 0.6 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat Metallophos_2 PF12850.7 KFM28601.1 - 0.00072 19.8 0.0 0.026 14.7 0.0 2.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TPR_16 PF13432.6 KFM28601.1 - 0.035 14.8 32.0 0.19 12.4 9.7 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 KFM28601.1 - 0.14 12.3 16.5 0.25 11.5 3.9 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat CPBP PF02517.16 KFM28602.1 - 3.7e-14 52.9 6.0 3.7e-14 52.9 6.0 2.7 3 1 0 3 3 3 1 CPBP intramembrane metalloprotease Rsm22 PF09243.10 KFM28604.1 - 9.6e-40 136.6 0.0 4.1e-29 101.7 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.6 KFM28604.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Glyco_transf_18 PF15024.6 KFM28604.1 - 0.13 10.8 0.0 0.18 10.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 18 DUF2052 PF09747.9 KFM28605.1 - 2.5e-13 50.6 3.5 4.8e-12 46.4 0.3 2.3 1 1 1 2 2 2 2 Coiled-coil domain containing protein (DUF2052) Pyrid_oxidase_2 PF13883.6 KFM28606.1 - 5.2e-16 59.1 0.0 1.2e-15 57.9 0.0 1.6 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF2470 PF10615.9 KFM28606.1 - 3.7e-13 49.9 0.0 6.2e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Putative_PNPOx PF01243.20 KFM28606.1 - 4.6e-08 33.1 0.0 1.4e-07 31.6 0.0 1.8 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Rhodanese PF00581.20 KFM28607.1 - 3e-21 75.9 0.0 3.9e-12 46.6 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain Reo_sigmaC PF04582.12 KFM28607.1 - 0.046 14.0 0.0 0.076 13.3 0.0 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein C-terminal domain MFS_1 PF07690.16 KFM28608.1 - 9e-25 87.3 50.2 9e-25 87.3 50.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 KFM28608.1 - 8.9e-18 63.9 17.3 1.1e-06 27.2 0.7 3.6 2 2 2 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 KFM28608.1 - 4.3e-09 35.8 24.2 4.4e-07 29.1 7.9 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter DUF4538 PF15061.6 KFM28608.1 - 0.0015 18.3 2.0 0.0023 17.7 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4538) MFS_4 PF06779.14 KFM28608.1 - 0.16 11.2 33.6 2.3 7.4 33.6 2.3 1 1 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB GHMP_kinases_N PF00288.26 KFM28609.1 - 1.6e-11 44.2 1.7 2.3e-11 43.7 0.0 2.1 3 0 0 3 3 3 1 GHMP kinases N terminal domain GalKase_gal_bdg PF10509.9 KFM28609.1 - 0.0039 16.7 0.0 0.0089 15.6 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Nop14 PF04147.12 KFM28610.1 - 7.7e-104 348.7 25.1 5.6e-61 206.9 11.9 3.0 2 1 1 3 3 3 3 Nop14-like family Ribosomal_L25p PF01386.19 KFM28610.1 - 0.16 12.5 0.4 0.51 10.9 0.4 1.9 1 0 0 1 1 1 0 Ribosomal L25p family RSN1_7TM PF02714.15 KFM28611.1 - 1e-31 110.3 23.9 2.1e-16 60.1 9.7 2.5 2 1 0 2 2 2 2 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KFM28611.1 - 6.2e-30 104.0 1.3 6.2e-30 104.0 1.3 2.5 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KFM28611.1 - 5.5e-09 36.5 0.0 8.9e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter FaeA PF04703.12 KFM28611.1 - 0.2 12.1 0.9 2.7 8.4 0.1 2.5 2 0 0 2 2 2 0 FaeA-like protein PSS PF03034.15 KFM28612.1 - 3.4e-102 341.9 3.4 4.2e-102 341.6 3.4 1.1 1 0 0 1 1 1 1 Phosphatidyl serine synthase Pyridoxal_deC PF00282.19 KFM28613.1 - 4.6e-59 200.0 0.0 1.1e-56 192.1 0.0 2.2 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KFM28613.1 - 0.0046 16.0 0.0 0.0084 15.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Lipase_3 PF01764.25 KFM28616.1 - 1.3e-35 122.3 0.0 6.8e-30 103.8 0.0 3.2 2 1 1 3 3 3 2 Lipase (class 3) Abhydrolase_6 PF12697.7 KFM28616.1 - 0.014 16.0 1.3 0.014 16.0 1.3 3.0 3 0 0 3 3 3 0 Alpha/beta hydrolase family Metallophos_2 PF12850.7 KFM28617.1 - 9.1e-05 22.7 0.0 0.15 12.2 0.0 2.5 3 0 0 3 3 3 2 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KFM28617.1 - 0.00019 22.0 0.1 0.00082 19.9 0.1 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1897 PF09005.10 KFM28617.1 - 0.024 14.1 0.1 0.024 14.1 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1897) Ribosomal_L13 PF00572.18 KFM28618.1 - 5.1e-42 143.1 0.0 6.9e-42 142.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 PNMA PF14893.6 KFM28618.1 - 0.097 12.1 0.0 0.28 10.5 0.0 1.6 2 0 0 2 2 2 0 PNMA Ribosomal_S15 PF00312.22 KFM28619.1 - 2.1e-28 98.3 0.4 2.8e-28 97.9 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S15 CALCOCO1 PF07888.11 KFM28619.1 - 0.028 13.3 0.4 0.031 13.1 0.4 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like zf-C3HC4_3 PF13920.6 KFM28620.1 - 0.004 17.0 8.5 0.0076 16.1 8.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM28620.1 - 0.012 16.0 12.7 0.02 15.2 12.7 1.4 1 0 0 1 1 1 0 Ring finger domain KapB PF08810.10 KFM28620.1 - 0.059 13.5 0.1 0.41 10.8 0.0 2.0 2 0 0 2 2 2 0 Kinase associated protein B zf-C3HC4 PF00097.25 KFM28620.1 - 0.15 12.0 11.8 0.24 11.3 11.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF92 PF01940.16 KFM28621.1 - 9.8e-64 215.0 7.0 1.4e-63 214.4 7.0 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF92 DAP_epimerase PF01678.19 KFM28621.1 - 0.054 13.7 0.1 0.11 12.7 0.1 1.4 1 0 0 1 1 1 0 Diaminopimelate epimerase Na_sulph_symp PF00939.19 KFM28622.1 - 2.8e-109 366.3 34.1 3.3e-109 366.1 34.1 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 KFM28622.1 - 1.6e-11 44.0 43.2 2e-11 43.7 39.4 2.3 1 1 1 2 2 2 2 Citrate transporter SNARE_assoc PF09335.11 KFM28623.1 - 4.5e-10 40.1 1.4 1.3e-09 38.6 1.4 1.7 1 0 0 1 1 1 1 SNARE associated Golgi protein MerE PF05052.12 KFM28623.1 - 4.9 7.2 10.4 0.89 9.5 0.8 2.6 2 0 0 2 2 2 0 MerE protein WD40 PF00400.32 KFM28624.1 - 4.5e-26 90.6 3.7 0.00021 22.0 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM28624.1 - 0.00081 19.6 0.0 2.7 8.3 0.0 3.9 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nop PF01798.18 KFM28625.1 - 7.6e-72 241.5 0.2 7.8e-62 208.7 0.0 2.4 1 1 1 2 2 2 2 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KFM28625.1 - 7.6e-19 67.9 0.8 7.6e-19 67.9 0.8 2.7 3 0 0 3 3 3 1 NOP5NT (NUC127) domain Cdh1_DBD_1 PF18196.1 KFM28625.1 - 1.2 9.5 10.3 2.6 8.4 10.3 1.5 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 RNA_polI_A34 PF08208.11 KFM28625.1 - 9.7 6.2 19.6 22 5.1 19.6 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Cullin PF00888.22 KFM28626.1 - 5.7e-158 527.3 4.6 7.9e-158 526.8 4.6 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KFM28626.1 - 9.3e-24 83.2 6.7 1e-23 83.1 4.7 2.3 2 1 0 2 2 2 1 Cullin protein neddylation domain ESCRT-II PF05871.12 KFM28626.1 - 0.077 13.3 0.1 0.49 10.7 0.0 2.2 2 0 0 2 2 2 0 ESCRT-II complex subunit K_channel_TID PF07941.11 KFM28626.1 - 0.45 11.0 3.0 2.6 8.6 1.2 2.3 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain ADH_N PF08240.12 KFM28627.1 - 4.5e-22 78.0 0.1 8.8e-22 77.1 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFM28627.1 - 4.8e-21 75.1 0.0 7.3e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KFM28627.1 - 3.1e-09 36.6 0.0 4.5e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KFM28627.1 - 5.3e-06 25.9 1.6 1.6e-05 24.3 0.0 2.1 1 1 1 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 KFM28627.1 - 2.7e-05 25.2 0.0 5.6e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 KFM28627.1 - 0.00042 20.6 0.1 0.00068 19.9 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_3 PF03447.16 KFM28627.1 - 0.012 16.3 0.1 0.024 15.3 0.1 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 KFM28627.1 - 0.013 14.8 0.0 0.096 11.9 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KFM28627.1 - 0.018 14.4 0.0 0.068 12.5 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AroM PF07302.11 KFM28627.1 - 0.029 13.8 0.0 0.045 13.2 0.0 1.2 1 0 0 1 1 1 0 AroM protein Methyltransf_25 PF13649.6 KFM28627.1 - 0.037 14.7 0.4 0.084 13.6 0.1 1.7 2 0 0 2 2 2 0 Methyltransferase domain Glyco_tran_WecB PF03808.13 KFM28627.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Ribosomal_L29 PF00831.23 KFM28628.1 - 1.4e-19 69.8 0.5 1.4e-19 69.8 0.5 2.2 2 1 0 2 2 2 1 Ribosomal L29 protein Cas_Csx8 PF09657.10 KFM28628.1 - 0.014 14.4 0.2 0.017 14.2 0.2 1.1 1 0 0 1 1 1 0 CRISPR-associated protein Csx8 (Cas_Csx8) BolA PF01722.18 KFM28629.1 - 2.7e-15 56.4 0.2 3.9e-15 55.9 0.2 1.3 1 1 0 1 1 1 1 BolA-like protein YwqJ-deaminase PF14431.6 KFM28629.1 - 0.016 15.4 0.3 0.018 15.2 0.3 1.1 1 0 0 1 1 1 0 YwqJ-like deaminase MMS1_N PF10433.9 KFM28630.1 - 2.6e-17 62.7 0.0 3.6e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KFM28631.1 - 4.6e-31 108.3 0.0 2.9e-15 56.4 0.0 2.5 2 1 0 2 2 2 2 CPSF A subunit region SBP PF03110.14 KFM28633.1 - 3.1e-16 59.4 6.1 3.8e-16 59.2 6.1 1.1 1 0 0 1 1 1 1 SBP domain Nudix_N_2 PF14803.6 KFM28633.1 - 0.065 13.2 1.1 0.11 12.5 1.1 1.4 1 0 0 1 1 1 0 Nudix N-terminal Maf PF02545.14 KFM28634.1 - 5.2e-57 192.3 0.0 5.8e-57 192.2 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein Hydrolase PF00702.26 KFM28634.1 - 0.028 14.7 0.0 0.034 14.5 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase THOC2_N PF16134.5 KFM28635.1 - 9.9e-19 67.4 0.0 1.7e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus TatC PF00902.18 KFM28636.1 - 4.9e-59 199.6 13.2 6e-59 199.3 13.2 1.1 1 0 0 1 1 1 1 Sec-independent protein translocase protein (TatC) DUF2919 PF11143.8 KFM28636.1 - 0.044 14.1 4.0 0.087 13.1 4.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2919) YoaP PF14268.6 KFM28636.1 - 0.069 12.7 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 YoaP-like Sacchrp_dh_NADP PF03435.18 KFM28638.1 - 4.2e-15 56.2 0.0 7.2e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 KFM28638.1 - 1.3e-07 31.4 0.0 2.2e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFM28638.1 - 3.5e-07 30.3 0.0 6.2e-07 29.5 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KFM28638.1 - 0.013 14.5 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KFM28638.1 - 0.025 14.1 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family LPD23 PF18838.1 KFM28638.1 - 0.061 13.1 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 Large polyvalent protein associated domain 23 GDP_Man_Dehyd PF16363.5 KFM28638.1 - 0.2 11.0 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase PRK PF00485.18 KFM28639.1 - 2.8e-24 86.0 5.1 1.1e-23 84.0 1.4 2.6 2 1 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family CYTH PF01928.21 KFM28639.1 - 2.7e-13 50.3 0.0 4.3e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 CYTH domain AAA_24 PF13479.6 KFM28639.1 - 0.0075 16.0 0.0 0.02 14.6 0.0 1.6 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KFM28639.1 - 0.041 13.1 0.0 0.075 12.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain KAP_NTPase PF07693.14 KFM28639.1 - 0.2 10.8 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain tRNA-synt_1g PF09334.11 KFM28640.1 - 1e-86 291.2 0.0 1.1e-32 113.3 0.0 3.0 2 1 1 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KFM28640.1 - 4.6e-16 58.2 0.1 1.2e-09 37.0 0.0 3.4 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 KFM28640.1 - 1.6e-08 34.3 0.0 0.00091 18.7 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain HECT PF00632.25 KFM28641.1 - 4.5e-18 65.8 0.0 6e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HECT PF00632.25 KFM28642.1 - 1.1e-61 209.0 0.0 1.2e-61 208.9 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RGM_C PF06534.13 KFM28642.1 - 0.068 12.7 0.0 0.099 12.1 0.0 1.2 1 0 0 1 1 1 0 Repulsive guidance molecule (RGM) C-terminus Glyco_transf_28 PF03033.20 KFM28643.1 - 1.1e-11 44.9 0.0 1.8e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_tran_28_C PF04101.16 KFM28643.1 - 0.057 13.4 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain AAA_33 PF13671.6 KFM28644.1 - 3.1e-06 27.4 0.1 1.7e-05 25.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KFM28644.1 - 0.00011 22.7 0.0 0.00021 21.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KFM28644.1 - 0.0012 19.2 0.0 0.0028 18.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KFM28644.1 - 0.0024 17.8 0.4 0.012 15.5 0.1 2.2 3 0 0 3 3 2 1 RsgA GTPase AAA_24 PF13479.6 KFM28644.1 - 0.0033 17.2 0.0 0.0054 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain DRIM PF07539.12 KFM28644.1 - 0.0037 15.6 0.0 0.0053 15.1 0.0 1.2 1 0 0 1 1 1 1 Down-regulated in metastasis AAA_28 PF13521.6 KFM28644.1 - 0.0073 16.6 0.1 0.014 15.7 0.1 1.5 1 0 0 1 1 1 1 AAA domain PAC4 PF16093.5 KFM28644.1 - 0.014 15.5 1.4 0.019 15.1 0.2 1.8 2 0 0 2 2 1 0 Proteasome assembly chaperone 4 AAA_22 PF13401.6 KFM28644.1 - 0.017 15.4 0.0 0.032 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFM28644.1 - 0.018 15.6 0.3 0.034 14.6 0.3 1.4 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 KFM28644.1 - 0.046 13.7 0.2 0.12 12.3 0.2 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KFM28644.1 - 0.046 13.4 0.1 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 KFM28644.1 - 0.049 13.2 0.1 0.12 11.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KFM28644.1 - 0.05 13.4 0.4 0.1 12.3 0.4 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 KFM28644.1 - 0.069 13.1 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_16 PF13191.6 KFM28644.1 - 0.086 13.2 4.8 0.12 12.7 3.1 2.5 2 1 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 KFM28644.1 - 0.11 11.8 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin APS_kinase PF01583.20 KFM28644.1 - 0.11 12.4 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase V-ATPase_H_N PF03224.14 KFM28644.1 - 0.12 11.7 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 V-ATPase subunit H RNA_helicase PF00910.22 KFM28644.1 - 0.12 12.8 0.1 0.28 11.6 0.0 1.6 2 0 0 2 2 1 0 RNA helicase Cytidylate_kin PF02224.18 KFM28644.1 - 0.19 11.5 0.1 0.31 10.7 0.1 1.3 1 0 0 1 1 1 0 Cytidylate kinase Histone PF00125.24 KFM28645.1 - 1.1e-58 197.3 0.5 1.3e-41 142.1 0.8 2.0 1 1 1 2 2 2 2 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KFM28645.1 - 2.4e-19 68.7 1.3 5.4e-19 67.6 1.3 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KFM28645.1 - 2.2e-06 27.8 0.0 9.3e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PAF PF15715.5 KFM28645.1 - 0.00053 20.6 1.7 0.00053 20.6 1.7 1.5 2 0 0 2 2 2 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 KFM28647.1 - 2e-08 34.3 0.1 2.5e-08 34.0 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KFM28647.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 KFM28647.1 - 0.00022 21.3 0.1 0.00031 20.8 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.13 KFM28647.1 - 0.0011 18.9 0.1 0.0017 18.4 0.1 1.2 1 0 0 1 1 1 1 Bromodomain associated CBFD_NFYB_HMF PF00808.23 KFM28647.1 - 0.0013 19.0 0.0 0.0022 18.3 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFM28647.1 - 0.0015 18.9 0.1 0.0017 18.8 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KFM28647.1 - 0.033 14.3 0.0 0.037 14.1 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Ig_mannosidase PF17753.1 KFM28648.1 - 2.7e-10 39.8 0.0 1.2e-09 37.8 0.0 2.0 2 0 0 2 2 2 1 Ig-fold domain Glyco_hydro_2 PF00703.21 KFM28648.1 - 0.00046 20.8 0.0 0.001 19.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 KFM28648.1 - 0.04 13.8 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 KFM28648.1 - 0.18 10.9 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain LCM PF04072.14 KFM28649.1 - 1.1e-26 93.9 0.0 1.9e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase RSN1_7TM PF02714.15 KFM28650.1 - 1.2e-68 231.4 26.4 2.5e-68 230.4 26.4 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KFM28650.1 - 9.6e-24 83.9 19.5 1.1e-12 47.9 0.6 4.4 3 1 1 4 4 4 3 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KFM28650.1 - 1e-19 71.4 0.1 4.9e-19 69.2 0.0 2.0 2 0 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter CclA_1 PF16942.5 KFM28650.1 - 0.44 10.8 4.2 0.19 12.0 1.3 1.9 2 0 0 2 2 2 0 Putative cyclic bacteriocin C2 PF00168.30 KFM28651.1 - 7.3e-32 109.7 1.0 1.8e-14 53.8 0.1 2.9 2 1 0 2 2 2 2 C2 domain SMP_LBD PF17047.5 KFM28651.1 - 5e-12 45.7 0.0 1e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain LSM PF01423.22 KFM28654.1 - 9.7e-17 60.4 0.1 1.3e-16 60.0 0.1 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KFM28654.1 - 0.02 14.5 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Hfq protein SOUL PF04832.12 KFM28655.1 - 2.9e-19 69.9 0.1 4e-17 62.9 0.1 2.4 1 1 0 1 1 1 1 SOUL heme-binding protein Exo_endo_phos PF03372.23 KFM28655.1 - 1.5e-17 63.9 1.4 4.1e-10 39.6 0.0 2.4 1 1 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family UBM PF14377.6 KFM28655.1 - 0.084 12.4 0.4 0.2 11.1 0.4 1.7 1 0 0 1 1 1 0 Ubiquitin binding region NDK PF00334.19 KFM28656.1 - 1.3e-48 164.4 0.0 1.6e-48 164.2 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Kdo PF06293.14 KFM28657.1 - 3.1e-14 52.8 0.0 4.2e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KFM28657.1 - 1.4e-10 41.0 0.0 1.5e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KFM28657.1 - 9.6e-10 38.8 0.7 0.00028 20.9 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 KFM28657.1 - 1.2e-08 34.8 0.0 1.7e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.17 KFM28657.1 - 1.1e-06 28.2 0.0 1.4e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase EcKinase PF02958.20 KFM28657.1 - 0.002 17.5 0.0 0.0035 16.7 0.0 1.4 1 1 0 1 1 1 1 Ecdysteroid kinase WaaY PF06176.11 KFM28657.1 - 0.034 13.8 0.0 0.042 13.5 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Kinase-like PF14531.6 KFM28657.1 - 0.13 11.5 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Y_phosphatase3 PF13350.6 KFM28660.1 - 1.7e-37 129.6 0.1 3.3e-37 128.7 0.1 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family Succ_CoA_lig PF13607.6 KFM28660.1 - 0.1 12.4 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain Noc2 PF03715.13 KFM28661.1 - 7e-93 311.1 0.0 8.9e-93 310.8 0.0 1.1 1 0 0 1 1 1 1 Noc2p family Menin PF05053.13 KFM28661.1 - 1.8 6.8 5.9 2.6 6.3 5.9 1.1 1 0 0 1 1 1 0 Menin FMO-like PF00743.19 KFM28662.1 - 1.4e-59 202.0 0.0 2.3e-42 145.1 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFM28662.1 - 2.5e-16 59.8 0.0 8.9e-14 51.4 0.0 2.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFM28662.1 - 3.3e-09 36.4 0.0 9.4e-09 34.9 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFM28662.1 - 5.1e-07 29.2 0.4 1.7e-06 27.5 0.1 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KFM28662.1 - 1.3e-06 28.5 0.4 1.6e-05 25.0 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KFM28662.1 - 0.00031 20.8 6.5 0.85 9.6 3.9 4.1 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 KFM28662.1 - 0.00046 19.9 1.4 0.14 11.8 0.0 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase PCI PF01399.27 KFM28663.1 - 7.1e-11 42.6 0.0 1.3e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 PCI domain Dimerisation2 PF16864.5 KFM28663.1 - 0.077 13.0 0.4 0.69 9.9 0.1 2.3 2 0 0 2 2 2 0 Dimerisation domain ARPC4 PF05856.12 KFM28664.1 - 1e-45 155.4 0.0 1.3e-45 155.0 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) RNA_pol_Rpc34 PF05158.12 KFM28665.1 - 3.9e-61 207.3 1.6 4.8e-46 157.7 0.1 2.8 1 1 1 2 2 2 2 RNA polymerase Rpc34 subunit HTH_24 PF13412.6 KFM28665.1 - 3.8e-05 23.2 0.2 0.0018 17.8 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding TrmB PF01978.19 KFM28665.1 - 0.0011 18.8 0.1 0.0033 17.3 0.0 1.9 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB RPA_C PF08784.11 KFM28665.1 - 0.0013 19.3 0.1 0.003 18.2 0.1 1.6 2 0 0 2 2 2 1 Replication protein A C terminal B-block_TFIIIC PF04182.12 KFM28665.1 - 0.002 18.3 0.0 0.0036 17.4 0.0 1.4 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC MarR PF01047.22 KFM28665.1 - 0.003 17.4 0.0 0.0059 16.5 0.0 1.5 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 KFM28665.1 - 0.017 15.0 0.0 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 MarR family Penicillinase_R PF03965.16 KFM28665.1 - 0.09 13.1 0.0 3 8.2 0.0 2.5 2 0 0 2 2 2 0 Penicillinase repressor HTH_46 PF15977.5 KFM28665.1 - 0.1 12.6 0.3 0.43 10.6 0.0 2.2 2 1 1 3 3 3 0 Winged helix-turn-helix DNA binding Peptidase_S66 PF02016.15 KFM28665.1 - 0.11 12.6 0.1 0.61 10.2 0.0 2.0 2 0 0 2 2 2 0 LD-carboxypeptidase N-terminal domain DUF2188 PF09954.9 KFM28666.1 - 0.053 13.7 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) SET PF00856.28 KFM28667.1 - 4.2e-10 40.3 0.0 8.2e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 SET domain Hus1 PF04005.12 KFM28667.1 - 7e-09 35.2 0.0 4.9e-08 32.4 0.0 2.0 1 1 0 1 1 1 1 Hus1-like protein Nif11 PF07862.11 KFM28667.1 - 0.01 16.1 0.0 0.041 14.2 0.0 2.1 1 0 0 1 1 1 0 Nif11 domain DNA_pol3_tau_4 PF12168.8 KFM28667.1 - 0.17 12.5 1.1 0.33 11.5 0.1 2.0 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding GP38 PF05268.11 KFM28667.1 - 1.2 8.7 6.6 3.3 7.3 6.6 1.7 1 0 0 1 1 1 0 Phage tail fibre adhesin Gp38 CBM_20 PF00686.19 KFM28670.1 - 1.5e-17 63.2 0.0 2.5e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Starch binding domain SPX PF03105.19 KFM28670.1 - 0.45 10.4 8.2 0.6 10.0 8.2 1.3 1 0 0 1 1 1 0 SPX domain Ndc1_Nup PF09531.10 KFM28670.1 - 4.5 5.9 9.4 5.9 5.4 9.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Mitofilin PF09731.9 KFM28670.1 - 7.1 5.3 20.3 9.3 4.9 20.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Fasciclin PF02469.22 KFM28672.1 - 1.2e-25 90.2 0.0 5.8e-12 45.9 0.0 2.9 2 2 0 2 2 2 2 Fasciclin domain Fez1 PF06818.15 KFM28673.1 - 0.014 15.9 4.6 0.014 15.9 4.6 3.6 1 1 2 3 3 3 0 Fez1 RasGAP_C PF03836.15 KFM28673.1 - 0.05 13.7 2.7 0.063 13.4 0.5 2.3 2 1 0 2 2 2 0 RasGAP C-terminus EzrA PF06160.12 KFM28673.1 - 0.26 9.4 6.8 0.32 9.1 0.0 2.8 2 2 2 4 4 4 0 Septation ring formation regulator, EzrA GAS PF13851.6 KFM28673.1 - 5 6.4 28.4 2.8 7.2 0.3 4.9 3 2 1 5 5 5 0 Growth-arrest specific micro-tubule binding Csm1_N PF18504.1 KFM28673.1 - 5.8 7.3 15.9 8.3 6.8 0.3 5.7 5 2 1 7 7 7 0 Csm1 N-terminal domain 2-oxoacid_dh PF00198.23 KFM28674.1 - 1e-62 211.7 0.0 1.3e-62 211.3 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Exostosin PF03016.15 KFM28674.1 - 1.8e-16 60.2 0.0 1.6e-09 37.5 0.1 2.2 1 1 1 2 2 2 2 Exostosin family Biotin_lipoyl PF00364.22 KFM28674.1 - 7.6e-16 57.7 1.1 1.5e-15 56.7 1.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KFM28674.1 - 2.1e-15 56.8 0.8 7.2e-15 55.1 0.1 2.4 2 0 0 2 2 2 1 e3 binding domain GCV_H PF01597.19 KFM28674.1 - 0.18 11.7 0.1 0.39 10.6 0.1 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein Ribosomal_L7Ae PF01248.26 KFM28676.1 - 0.00011 21.9 0.1 0.00017 21.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family AAA PF00004.29 KFM28677.1 - 1.3e-44 151.9 0.1 6e-44 149.7 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KFM28677.1 - 2.6e-09 36.9 0.1 2.6e-08 33.7 0.0 2.5 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 KFM28677.1 - 2.4e-08 34.1 0.1 8.8e-08 32.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFM28677.1 - 2e-06 28.3 0.3 0.00012 22.5 0.0 2.5 1 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 KFM28677.1 - 6.7e-06 26.3 0.0 1.4e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_lid_3 PF17862.1 KFM28677.1 - 1.9e-05 24.3 0.0 4.7e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain DUF815 PF05673.13 KFM28677.1 - 3.6e-05 23.0 0.0 8.5e-05 21.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KFM28677.1 - 8.8e-05 22.8 0.4 0.0081 16.4 0.1 2.6 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 KFM28677.1 - 0.0002 21.2 0.0 0.00056 19.7 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KFM28677.1 - 0.00022 21.8 0.0 0.0007 20.2 0.0 2.0 2 0 0 2 2 1 1 AAA domain NTPase_1 PF03266.15 KFM28677.1 - 0.00039 20.4 0.1 0.033 14.1 0.0 2.6 3 0 0 3 3 3 1 NTPase AAA_28 PF13521.6 KFM28677.1 - 0.00056 20.2 0.0 0.0012 19.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KFM28677.1 - 0.00066 20.0 0.0 0.0013 19.1 0.0 1.5 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.17 KFM28677.1 - 0.00087 19.1 0.0 0.0025 17.6 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KFM28677.1 - 0.0019 17.6 0.1 0.0038 16.7 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 KFM28677.1 - 0.0038 17.0 0.1 0.01 15.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 KFM28677.1 - 0.0038 16.5 0.0 0.0083 15.4 0.0 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 KFM28677.1 - 0.0042 17.3 0.0 0.0085 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 KFM28677.1 - 0.0048 16.9 0.0 0.0098 15.9 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KFM28677.1 - 0.0067 16.2 0.1 0.015 15.0 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 KFM28677.1 - 0.0086 15.9 0.0 0.066 13.1 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KFM28677.1 - 0.011 15.4 0.1 0.19 11.4 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain NACHT PF05729.12 KFM28677.1 - 0.015 15.2 0.2 0.085 12.8 0.1 2.3 3 0 0 3 3 3 0 NACHT domain Parvo_NS1 PF01057.17 KFM28677.1 - 0.019 14.1 0.0 0.035 13.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 KFM28677.1 - 0.02 14.4 0.1 0.088 12.3 0.1 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 KFM28677.1 - 0.026 14.1 0.2 0.026 14.1 0.2 2.2 2 1 1 3 3 3 0 AAA domain AAA_14 PF13173.6 KFM28677.1 - 0.042 13.9 0.0 0.095 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KFM28677.1 - 0.059 12.8 0.1 2.2 7.7 0.0 2.5 3 0 0 3 3 2 0 Bacterial TniB protein ATPase_2 PF01637.18 KFM28677.1 - 0.06 13.3 0.0 2.2 8.1 0.0 2.4 1 1 0 2 2 2 0 ATPase domain predominantly from Archaea PhoH PF02562.16 KFM28677.1 - 0.088 12.2 0.1 0.2 11.1 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein ATPase PF06745.13 KFM28677.1 - 0.11 11.8 0.6 0.4 10.0 0.0 2.1 3 0 0 3 3 3 0 KaiC AAA_23 PF13476.6 KFM28677.1 - 0.15 12.6 0.2 12 6.4 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KFM28677.1 - 0.16 11.8 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Vps8 PF12816.7 KFM28678.1 - 8.1e-33 113.6 0.0 1.2e-32 113.0 0.0 1.2 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 KFM28678.1 - 1.6e-07 31.3 0.0 4.7e-05 23.3 0.0 2.3 2 0 0 2 2 2 2 Region in Clathrin and VPS TPR_7 PF13176.6 KFM28679.1 - 0.054 13.6 0.1 1.1 9.5 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Nucleoporin_N PF08801.11 KFM28680.1 - 3.6e-36 124.8 0.0 4.6e-36 124.5 0.0 1.0 1 0 0 1 1 1 1 Nup133 N terminal like PQQ_3 PF13570.6 KFM28680.1 - 0.017 15.6 0.2 0.062 13.8 0.2 1.9 1 0 0 1 1 1 0 PQQ-like domain zf-C2HC5 PF06221.13 KFM28680.1 - 1.5 8.8 4.6 0.28 11.2 0.4 2.0 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type Mis12 PF05859.12 KFM28681.1 - 4.3e-08 33.3 0.0 6.8e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Mis12 protein DEAD PF00270.29 KFM28682.1 - 1.6e-14 54.0 0.0 2.5e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM28682.1 - 3.4e-10 40.2 0.0 6.8e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KFM28682.1 - 1.7e-05 25.4 4.4 4.4e-05 24.1 4.4 1.7 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 KFM28682.1 - 0.2 11.7 0.0 0.35 10.8 0.0 1.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit CybS PF05328.12 KFM28683.1 - 6.2e-13 48.6 0.1 8.3e-13 48.2 0.1 1.2 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Branch PF02485.21 KFM28685.1 - 4.7e-70 235.9 4.5 9.4e-43 146.5 0.2 2.4 3 0 0 3 3 3 2 Core-2/I-Branching enzyme Branch PF02485.21 KFM28687.1 - 2.8e-19 69.6 0.2 5.5e-18 65.4 0.2 2.0 1 1 0 1 1 1 1 Core-2/I-Branching enzyme Branch PF02485.21 KFM28688.1 - 4.9e-20 72.1 0.0 2.3e-09 37.2 0.0 2.1 1 1 1 2 2 2 2 Core-2/I-Branching enzyme Sigma70_r2 PF04542.14 KFM28690.1 - 2.9e-15 55.8 0.0 6.6e-15 54.6 0.0 1.6 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 KFM28690.1 - 9.8e-13 47.4 0.0 1.2e-11 43.9 0.0 2.5 2 1 0 2 2 2 1 Sigma-70, region 4 TPP_enzyme_N PF02776.18 KFM28691.1 - 2.1e-53 180.5 0.1 1.3e-51 174.6 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KFM28691.1 - 1e-42 145.5 0.0 1.1e-41 142.2 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KFM28691.1 - 2.5e-34 118.0 0.1 5.3e-34 116.9 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain UQ_con PF00179.26 KFM28692.1 - 2.4e-24 85.6 0.0 2.7e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFM28692.1 - 0.0006 19.5 0.0 0.00074 19.2 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B FAD_binding_6 PF00970.24 KFM28693.1 - 9.6e-33 112.5 0.0 1.8e-32 111.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KFM28693.1 - 8.8e-32 110.0 0.0 2.3e-31 108.7 0.0 1.7 2 0 0 2 2 1 1 Oxidoreductase NAD-binding domain DUF1664 PF07889.12 KFM28693.1 - 5.3e-24 84.6 0.5 1.8e-23 82.9 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) Apolipoprotein PF01442.18 KFM28693.1 - 4.2e-05 23.5 0.5 6.8e-05 22.8 0.5 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain NAD_binding_6 PF08030.12 KFM28693.1 - 0.0004 20.5 0.0 0.0014 18.8 0.0 1.9 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Baculo_PEP_C PF04513.12 KFM28693.1 - 0.012 15.6 0.3 0.028 14.5 0.1 1.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MscS_porin PF12795.7 KFM28693.1 - 0.071 12.6 2.8 1.1 8.7 0.4 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain LPP PF04728.13 KFM28693.1 - 0.1 13.0 1.2 21 5.6 0.1 3.0 3 0 0 3 3 3 0 Lipoprotein leucine-zipper TM_helix PF05552.12 KFM28693.1 - 0.12 12.4 1.7 0.35 10.9 1.4 1.9 2 0 0 2 2 2 0 Conserved TM helix Seryl_tRNA_N PF02403.22 KFM28693.1 - 0.18 12.0 0.4 2.4 8.4 0.1 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CLZ PF16526.5 KFM28693.1 - 4.3 7.8 7.3 1.5 9.3 0.2 3.3 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels rRNA_proc-arch PF13234.6 KFM28694.1 - 2.1e-32 113.1 0.1 3e-32 112.6 0.1 1.2 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 KFM28694.1 - 4.4e-14 52.6 0.0 2.3e-09 37.2 0.0 2.4 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM28694.1 - 2.7e-07 30.9 0.0 4.2e-06 27.1 0.0 2.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.6 KFM28695.1 - 6e-08 32.6 5.8 6e-08 32.6 5.8 1.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFM28695.1 - 3.7e-05 24.0 5.8 6.9e-05 23.1 5.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KFM28695.1 - 4.7e-05 23.2 4.1 8.2e-05 22.4 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM28695.1 - 6.8e-05 22.8 4.3 0.0001 22.2 4.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KFM28695.1 - 7.4e-05 22.5 5.4 0.00013 21.8 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFM28695.1 - 0.00033 20.7 5.7 0.00061 19.9 4.7 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KFM28695.1 - 0.0077 16.1 6.2 0.015 15.1 6.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFM28695.1 - 0.048 13.5 8.2 0.057 13.3 6.8 1.8 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Rtf2 PF04641.12 KFM28695.1 - 0.083 12.2 1.6 0.1 11.9 1.6 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger Glyco_transf_49 PF13896.6 KFM28696.1 - 8.2e-21 74.7 0.1 1e-20 74.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan Glycos_transf_2 PF00535.26 KFM28696.1 - 0.0019 18.0 0.1 0.0082 16.0 0.0 1.9 2 1 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_49 PF13896.6 KFM28697.1 - 3.9e-38 131.6 0.0 1e-36 126.9 0.0 2.2 1 1 0 1 1 1 1 Glycosyl-transferase for dystroglycan Fip1 PF05182.13 KFM28697.1 - 2.8e-15 55.5 0.1 7.7e-15 54.1 0.1 1.8 1 0 0 1 1 1 1 Fip1 motif Acetyltransf_6 PF13480.7 KFM28697.1 - 0.0071 16.5 0.3 0.03 14.5 0.3 2.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Branch PF02485.21 KFM28699.1 - 5.5e-24 85.0 0.1 9.9e-24 84.2 0.1 1.3 1 0 0 1 1 1 1 Core-2/I-Branching enzyme LPD23 PF18838.1 KFM28699.1 - 0.058 13.2 0.0 3.3 7.5 0.0 2.3 2 0 0 2 2 2 0 Large polyvalent protein associated domain 23 Acetyltransf_1 PF00583.25 KFM28700.1 - 2.8e-09 37.2 0.1 3.6e-09 36.9 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KFM28700.1 - 1.1e-08 34.9 0.0 1.5e-08 34.5 0.0 1.3 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KFM28700.1 - 2.5e-08 33.9 0.1 3e-08 33.6 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFM28700.1 - 1.6e-07 31.7 0.0 1.9e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 KFM28700.1 - 0.0018 17.8 0.0 0.0025 17.3 0.0 1.3 1 1 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_4 PF13420.7 KFM28700.1 - 0.021 14.9 0.0 0.031 14.4 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KFM28700.1 - 0.022 14.9 0.0 0.025 14.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain BCDHK_Adom3 PF10436.9 KFM28701.1 - 2.8e-37 128.0 0.0 3.9e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KFM28701.1 - 5.6e-06 26.8 0.2 9.7e-05 22.8 0.2 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HA PF03457.14 KFM28702.1 - 1.5e-22 79.7 12.1 4.9e-13 49.2 0.0 6.1 5 1 1 6 6 6 5 Helicase associated domain EGF_CA PF07645.15 KFM28703.1 - 4.6e-11 42.7 20.9 1.1e-10 41.6 4.9 4.0 5 0 0 5 5 5 2 Calcium-binding EGF domain cEGF PF12662.7 KFM28703.1 - 6.3e-09 35.6 10.2 6e-05 22.9 3.8 2.9 2 0 0 2 2 2 2 Complement Clr-like EGF-like PA PF02225.22 KFM28703.1 - 5.5e-08 32.7 0.1 1.3e-07 31.5 0.1 1.6 1 0 0 1 1 1 1 PA domain hEGF PF12661.7 KFM28703.1 - 6.7e-07 29.7 10.9 0.0018 18.8 2.2 3.7 2 0 0 2 2 2 2 Human growth factor-like EGF FXa_inhibition PF14670.6 KFM28703.1 - 1.3e-05 25.3 5.5 1.3e-05 25.3 5.5 4.8 6 0 0 6 6 6 2 Coagulation Factor Xa inhibitory site EGF PF00008.27 KFM28703.1 - 0.00018 21.7 13.1 0.00036 20.8 1.5 3.8 4 0 0 4 4 4 2 EGF-like domain EGF_3 PF12947.7 KFM28703.1 - 0.00061 19.9 26.2 0.0022 18.1 5.2 3.5 3 0 0 3 3 3 2 EGF domain Tme5_EGF_like PF09064.10 KFM28703.1 - 0.25 11.3 15.5 0.19 11.6 1.8 2.9 2 0 0 2 2 2 0 Thrombomodulin like fifth domain, EGF-like zf-UBP_var PF17807.1 KFM28703.1 - 0.25 11.1 3.1 0.57 10.0 3.1 1.5 1 0 0 1 1 1 0 Variant UBP zinc finger NuA4 PF09340.10 KFM28704.1 - 1.4e-10 40.9 0.0 1.7e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Val_tRNA-synt_C PF10458.9 KFM28704.1 - 0.059 13.7 1.2 0.081 13.2 1.2 1.2 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm TPR_1 PF00515.28 KFM28705.1 - 1e-11 44.1 2.7 1.4e-05 24.7 0.5 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFM28705.1 - 2.2e-08 33.6 5.9 0.00013 21.8 1.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFM28705.1 - 0.00019 21.3 0.8 0.02 15.0 0.2 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFM28705.1 - 0.013 15.9 1.0 0.27 11.7 0.1 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFM28705.1 - 0.22 11.2 1.2 7.2 6.4 0.1 2.6 2 1 1 3 3 3 0 TPR repeat DUF4351 PF14261.6 KFM28705.1 - 1 9.5 3.3 1.4 9.0 1.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4351) TPR_9 PF13371.6 KFM28705.1 - 1.1 9.4 11.1 0.12 12.6 5.9 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat R3H PF01424.22 KFM28706.1 - 1.5e-09 37.7 0.0 2.4e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 R3H domain UCH PF00443.29 KFM28707.1 - 2e-22 79.9 0.0 4e-22 79.0 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFM28707.1 - 6.2e-10 39.2 0.0 6e-07 29.3 0.0 2.7 1 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Acetyltransf_1 PF00583.25 KFM28708.1 - 6.3e-08 32.9 0.0 9.8e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFM28708.1 - 3.6e-05 24.1 0.0 6.3e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFM28708.1 - 7.9e-05 22.6 0.0 0.00012 22.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFM28708.1 - 0.00069 19.5 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 KFM28708.1 - 0.021 15.0 0.0 0.032 14.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PolyA_pol PF01743.20 KFM28709.1 - 7e-22 78.2 0.0 1.3e-20 74.1 0.0 2.2 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 KFM28709.1 - 1.3e-08 34.5 0.0 2.4e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A SpoU_methylase PF00588.19 KFM28710.1 - 9.8e-20 71.2 0.0 2.4e-19 69.9 0.0 1.7 1 0 0 1 1 1 1 SpoU rRNA Methylase family TB2_DP1_HVA22 PF03134.19 KFM28712.1 - 3.9e-25 87.6 2.7 5.8e-25 87.0 2.7 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family zf-RING_2 PF13639.6 KFM28713.1 - 4e-13 49.5 8.1 9.1e-13 48.3 8.1 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KFM28713.1 - 1.9e-09 37.6 10.8 1.8e-08 34.5 10.8 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KFM28713.1 - 1.2e-07 31.7 0.9 1.2e-07 31.7 0.9 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFM28713.1 - 1.2e-07 31.5 5.7 1.2e-07 31.5 5.7 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM28713.1 - 1.4e-07 31.3 4.7 3.1e-07 30.2 4.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFM28713.1 - 4.4e-07 29.5 2.8 1.3e-06 28.0 2.8 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 KFM28713.1 - 1.7e-05 24.7 4.8 3.7e-05 23.6 4.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFM28713.1 - 2.9e-05 23.8 7.2 0.0001 22.1 7.3 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFM28713.1 - 0.00013 21.7 5.6 0.00025 20.8 5.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KFM28713.1 - 0.0005 20.1 5.3 0.0018 18.3 5.3 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KFM28713.1 - 0.0024 17.5 5.2 0.0044 16.6 5.2 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 KFM28713.1 - 0.0099 16.2 5.3 0.019 15.3 5.3 1.5 1 0 0 1 1 1 1 RING-like domain Rtf2 PF04641.12 KFM28713.1 - 0.041 13.2 0.1 0.041 13.2 0.1 1.6 2 0 0 2 2 2 0 Rtf2 RING-finger zf-C3HC4_4 PF15227.6 KFM28713.1 - 0.046 13.9 1.1 0.046 13.9 1.1 1.9 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KFM28713.1 - 0.29 11.0 3.1 0.61 9.9 3.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-HC5HC2H PF13771.6 KFM28713.1 - 0.65 10.3 4.1 0.19 12.0 0.3 1.9 2 1 1 3 3 2 0 PHD-like zinc-binding domain FANCL_C PF11793.8 KFM28713.1 - 1 9.6 4.4 2.8 8.2 4.4 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 KFM28713.1 - 2.1 8.6 6.9 5.8 7.1 6.9 1.8 1 1 0 1 1 1 0 RING-variant domain SRP54 PF00448.22 KFM28714.1 - 1.5e-72 243.4 0.7 2.2e-72 242.8 0.7 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 KFM28714.1 - 6.3e-27 94.1 1.4 6.3e-27 94.1 1.4 2.8 2 1 1 3 3 3 1 Signal peptide binding domain SRP54_N PF02881.19 KFM28714.1 - 2.3e-15 56.5 0.0 9e-15 54.7 0.0 2.1 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain CbiA PF01656.23 KFM28714.1 - 1.1e-07 32.0 0.0 4.1e-07 30.1 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.12 KFM28714.1 - 4.9e-06 26.0 0.1 1.2e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 Zeta toxin MeaB PF03308.16 KFM28714.1 - 7.3e-05 21.9 2.6 0.0022 17.0 2.6 2.4 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ArsA_ATPase PF02374.15 KFM28714.1 - 8.9e-05 21.8 2.3 0.0026 17.0 0.1 2.6 3 0 0 3 3 3 1 Anion-transporting ATPase AAA_31 PF13614.6 KFM28714.1 - 0.00025 21.0 0.6 0.00075 19.5 0.4 1.7 1 1 0 2 2 1 1 AAA domain AAA_33 PF13671.6 KFM28714.1 - 0.00066 19.9 0.0 0.0018 18.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFM28714.1 - 0.001 19.5 0.0 0.0022 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ParA PF10609.9 KFM28714.1 - 0.001 18.5 0.2 0.0025 17.3 0.1 1.7 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase AAA_30 PF13604.6 KFM28714.1 - 0.0011 18.7 2.5 0.0011 18.7 2.5 1.9 2 1 0 2 2 1 1 AAA domain APS_kinase PF01583.20 KFM28714.1 - 0.0021 18.0 0.0 0.006 16.5 0.0 1.8 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_24 PF13479.6 KFM28714.1 - 0.0022 17.7 0.0 0.0048 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 KFM28714.1 - 0.004 16.8 0.3 0.008 15.8 0.3 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 KFM28714.1 - 0.014 15.9 0.0 0.051 14.1 0.0 2.2 1 1 0 1 1 1 0 ABC transporter ResIII PF04851.15 KFM28714.1 - 0.018 15.0 0.1 0.041 13.9 0.1 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 KFM28714.1 - 0.02 13.8 0.1 0.049 12.5 0.1 1.6 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain 6PF2K PF01591.18 KFM28714.1 - 0.028 13.7 0.0 0.048 12.9 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_22 PF13401.6 KFM28714.1 - 0.029 14.6 0.2 0.12 12.7 0.2 2.0 1 1 0 1 1 1 0 AAA domain MobB PF03205.14 KFM28714.1 - 0.029 14.3 1.8 0.093 12.6 0.2 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATPase PF06745.13 KFM28714.1 - 0.035 13.4 0.2 0.073 12.4 0.2 1.5 1 1 0 1 1 1 0 KaiC NTPase_1 PF03266.15 KFM28714.1 - 0.037 13.9 0.5 0.19 11.6 0.1 2.1 2 0 0 2 2 2 0 NTPase AAA_5 PF07728.14 KFM28714.1 - 0.046 13.7 0.3 0.21 11.6 0.2 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KFM28714.1 - 0.049 13.2 2.9 0.45 10.0 2.9 2.4 1 1 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 KFM28714.1 - 0.07 12.8 2.5 0.13 11.9 0.2 2.2 2 0 0 2 2 2 0 Thymidylate kinase AAA_18 PF13238.6 KFM28714.1 - 0.072 13.6 0.1 0.17 12.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KFM28714.1 - 0.089 13.0 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 KFM28714.1 - 0.092 12.2 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 TIP49 PF06068.13 KFM28714.1 - 0.11 11.7 0.1 0.23 10.6 0.1 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA PF00004.29 KFM28714.1 - 0.12 12.7 0.1 0.33 11.4 0.1 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CLP1_P PF16575.5 KFM28714.1 - 0.13 12.0 0.1 7.3 6.3 0.0 2.3 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop ACT PF01842.25 KFM28715.1 - 5.5e-08 32.4 0.1 0.00021 21.0 0.0 2.5 2 0 0 2 2 2 2 ACT domain ACT_4 PF13291.6 KFM28715.1 - 0.0022 18.6 1.0 0.022 15.4 0.2 2.5 2 1 1 3 3 3 1 ACT domain ACT_6 PF13740.6 KFM28715.1 - 0.055 13.5 0.1 0.19 11.7 0.1 1.9 1 1 0 1 1 1 0 ACT domain RNA_pol_I_A49 PF06870.12 KFM28716.1 - 3.2e-21 75.6 0.0 1e-17 64.1 0.0 2.0 1 1 1 2 2 2 2 A49-like RNA polymerase I associated factor ABC2_membrane PF01061.24 KFM28717.1 - 7.1e-31 107.3 22.1 7.1e-31 107.3 22.1 1.9 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 KFM28717.1 - 3.7e-20 72.8 0.1 9.4e-20 71.5 0.0 1.7 2 0 0 2 2 2 1 ABC transporter ABC2_membrane_3 PF12698.7 KFM28717.1 - 0.0013 18.0 22.2 0.0013 18.0 22.2 1.5 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 KFM28717.1 - 0.0014 18.5 0.1 0.33 10.7 0.1 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KFM28717.1 - 0.0029 18.0 0.3 0.0055 17.1 0.3 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 KFM28717.1 - 0.18 11.4 0.1 0.52 9.8 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KFM28717.1 - 0.2 12.2 0.1 0.41 11.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KFM28717.1 - 0.61 9.9 3.0 0.39 10.5 0.4 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain WD40 PF00400.32 KFM28718.1 - 5.1e-09 36.6 5.0 0.48 11.4 0.1 6.5 6 1 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM28718.1 - 0.0024 18.1 0.0 8 6.8 0.0 3.9 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Pro_isomerase PF00160.21 KFM28719.1 - 2.7e-10 40.7 0.0 5.2e-10 39.8 0.0 1.4 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Kelch_3 PF13415.6 KFM28720.1 - 7.6e-26 89.8 14.1 6.5e-08 32.7 0.2 7.6 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_4 PF13418.6 KFM28720.1 - 3.3e-23 81.4 9.7 1.8e-06 27.8 0.0 6.5 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 KFM28720.1 - 4.4e-22 77.6 1.9 1.9e-05 24.5 0.0 6.9 7 0 0 7 7 7 4 Kelch motif Kelch_6 PF13964.6 KFM28720.1 - 8e-17 60.9 0.8 1.5e-05 25.1 0.0 5.7 5 1 1 6 6 6 3 Kelch motif Kelch_1 PF01344.25 KFM28720.1 - 6.2e-16 57.7 5.5 8.4e-07 28.5 0.0 5.7 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 KFM28720.1 - 9.2e-15 54.0 1.8 2.2e-05 24.2 0.0 5.2 6 0 0 6 6 6 3 Kelch motif PQQ_3 PF13570.6 KFM28720.1 - 0.043 14.3 4.1 63 4.2 0.7 4.2 3 1 0 3 3 3 0 PQQ-like domain Sex_peptide PF08138.11 KFM28720.1 - 0.071 13.3 0.9 0.34 11.1 0.3 2.2 2 0 0 2 2 2 0 Sex peptide (SP) family T3SS_ExsE PF18286.1 KFM28721.1 - 0.0035 17.2 5.3 0.057 13.4 0.3 3.4 3 0 0 3 3 3 2 Type III secretion system ExsE LZ_Tnp_IS481 PF13011.6 KFM28721.1 - 1.1 9.9 4.8 1.4 9.5 0.5 2.9 2 1 1 3 3 3 0 leucine-zipper of insertion element IS481 Pkinase PF00069.25 KFM28722.1 - 3.3e-12 46.3 0.0 5.3e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM28722.1 - 0.001 18.4 0.0 0.072 12.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Cm_res_leader PF08077.11 KFM28722.1 - 3.5 8.0 5.3 25 5.5 0.1 4.1 3 0 0 3 3 3 0 Chloramphenicol resistance gene leader peptide PI31_Prot_N PF11566.8 KFM28723.1 - 2.1e-08 34.1 0.0 3.6e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal Actin PF00022.19 KFM28724.1 - 1.4e-145 485.0 0.0 4.5e-145 483.3 0.0 1.6 1 1 0 1 1 1 1 Actin Myb_DNA-binding PF00249.31 KFM28725.1 - 0.00012 22.2 0.0 0.00025 21.2 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 KFM28725.1 - 0.0099 15.9 0.3 0.018 15.1 0.3 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFM28725.1 - 0.17 12.1 0.0 0.3 11.4 0.0 1.3 1 0 0 1 1 1 0 Myb-like DNA-binding domain PK PF00224.21 KFM28728.1 - 1.4e-56 191.9 0.0 1.9e-56 191.4 0.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KFM28728.1 - 1.5e-19 70.4 0.1 3.5e-19 69.2 0.1 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain Abhydrolase_2 PF02230.16 KFM28729.1 - 2.5e-34 119.0 0.0 1.4e-29 103.4 0.0 2.1 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KFM28729.1 - 1.1e-10 41.2 0.1 6.9e-05 22.2 0.0 2.8 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KFM28729.1 - 8.7e-06 25.4 0.0 0.0012 18.3 0.0 2.2 1 1 1 2 2 2 1 Prolyl oligopeptidase family SAP PF02037.27 KFM28729.1 - 9.8e-06 25.2 0.2 2.5e-05 23.9 0.2 1.6 1 0 0 1 1 1 1 SAP domain DLH PF01738.18 KFM28729.1 - 1.7e-05 24.5 0.0 2.3e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Esterase PF00756.20 KFM28729.1 - 6.9e-05 22.6 0.0 0.00022 20.9 0.0 1.7 2 0 0 2 2 2 1 Putative esterase Abhydrolase_1 PF00561.20 KFM28729.1 - 0.00078 19.2 0.1 0.022 14.4 0.1 2.4 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KFM28729.1 - 0.001 19.0 0.0 0.011 15.6 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFM28729.1 - 0.0017 19.0 4.0 0.0034 18.0 4.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.22 KFM28729.1 - 0.01 15.8 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 Cutinase FSH1 PF03959.13 KFM28729.1 - 0.016 14.9 0.0 0.059 13.0 0.0 2.0 1 1 1 2 2 2 0 Serine hydrolase (FSH1) DUF2974 PF11187.8 KFM28729.1 - 0.029 13.9 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Ish1 PF10281.9 KFM28729.1 - 0.069 13.5 0.0 0.19 12.1 0.0 1.8 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein LIP PF03583.14 KFM28729.1 - 0.11 11.8 0.0 1 8.6 0.0 2.0 2 0 0 2 2 2 0 Secretory lipase TAL_effector PF03377.13 KFM28729.1 - 0.15 12.4 0.4 0.3 11.4 0.4 1.5 1 0 0 1 1 1 0 TAL effector repeat Aa_trans PF01490.18 KFM28730.1 - 4.6e-33 114.5 19.7 7e-33 113.9 19.7 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Lipase_3 PF01764.25 KFM28731.1 - 1e-26 93.5 0.0 5e-17 62.1 0.0 2.2 2 0 0 2 2 2 2 Lipase (class 3) Senescence PF06911.12 KFM28731.1 - 0.49 10.7 4.7 1.2 9.4 4.2 1.9 1 1 0 1 1 1 0 Senescence-associated protein SLC35F PF06027.12 KFM28732.1 - 2.7e-58 197.9 2.5 4e-57 194.0 2.5 1.9 1 1 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 KFM28732.1 - 0.00034 19.7 0.0 0.00059 18.9 0.0 1.3 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like VASt PF16016.5 KFM28733.1 - 2.2e-12 47.6 0.0 3e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain Pex24p PF06398.11 KFM28733.1 - 1.8e-10 40.4 0.2 5.5e-10 38.8 0.3 1.6 2 0 0 2 2 2 1 Integral peroxisomal membrane peroxin Bac_surface_Ag PF01103.23 KFM28735.1 - 3.3e-35 122.1 0.0 7.6e-35 120.9 0.0 1.6 1 1 0 1 1 1 1 Surface antigen POTRA PF07244.15 KFM28735.1 - 6.7e-18 65.0 0.0 3.1e-06 27.6 0.0 3.3 3 0 0 3 3 3 3 Surface antigen variable number repeat POTRA_2 PF08479.11 KFM28735.1 - 0.00096 18.9 0.1 0.0032 17.3 0.1 1.9 1 0 0 1 1 1 1 POTRA domain, ShlB-type Polyketide_cyc PF03364.20 KFM28739.1 - 3.4e-22 79.0 0.0 4.5e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 KFM28739.1 - 1e-05 25.9 0.0 1.4e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Alpha-amylase_C PF02806.18 KFM28740.1 - 3.9e-17 62.5 0.0 9.1e-17 61.3 0.0 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 KFM28740.1 - 5.9e-13 49.0 0.0 1.2e-12 48.0 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 KFM28740.1 - 9e-10 38.6 0.0 2.6e-07 30.5 0.0 2.2 1 1 1 2 2 2 2 Alpha amylase, catalytic domain AP2 PF00847.20 KFM28745.1 - 8.3e-15 54.8 16.8 1.9e-09 37.6 2.2 3.3 3 0 0 3 3 3 3 AP2 domain AAA PF00004.29 KFM28746.1 - 2.5e-41 141.2 0.0 5.3e-41 140.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Peptidase_M41 PF01434.18 KFM28746.1 - 1.2e-21 77.4 0.0 7.7e-17 61.8 0.0 2.5 2 0 0 2 2 2 2 Peptidase family M41 AAA_lid_3 PF17862.1 KFM28746.1 - 6.2e-10 38.7 0.5 6.2e-09 35.5 0.0 2.6 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 KFM28746.1 - 0.00049 20.1 0.0 0.002 18.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KFM28746.1 - 0.0017 18.6 0.5 0.26 11.6 0.1 2.9 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.13 KFM28746.1 - 0.0024 17.1 0.1 0.0044 16.3 0.1 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 KFM28746.1 - 0.0024 17.6 0.0 0.0076 16.0 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KFM28746.1 - 0.0025 18.2 0.1 0.23 11.9 0.1 2.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 KFM28746.1 - 0.066 12.7 0.3 7.1 6.1 0.1 2.5 2 1 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 KFM28746.1 - 0.11 13.0 0.0 0.29 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KFM28746.1 - 0.11 11.7 0.1 0.2 10.9 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.26 KFM28746.1 - 0.17 11.6 0.0 0.41 10.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain YbaB_DNA_bd PF02575.16 KFM28747.1 - 6.8e-17 61.5 5.6 8.4e-17 61.2 5.6 1.1 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family Exotox-A_target PF09102.10 KFM28747.1 - 0.066 13.2 0.9 0.11 12.5 0.9 1.4 1 1 0 1 1 1 0 Exotoxin A, targeting CtIP_N PF10482.9 KFM28747.1 - 0.094 12.8 0.3 1.9 8.5 0.0 2.1 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain ERp29 PF07749.12 KFM28747.1 - 0.98 10.4 3.8 0.97 10.4 0.3 2.1 1 1 1 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain 2OG-FeII_Oxy_3 PF13640.6 KFM28748.1 - 4.3e-22 78.8 0.0 6.7e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KFM28748.1 - 8.3e-09 35.8 0.0 1.3e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RPA_interact_C PF14768.6 KFM28748.1 - 0.083 13.5 0.5 0.16 12.5 0.5 1.5 1 0 0 1 1 1 0 Replication protein A interacting C-terminal ShK PF01549.24 KFM28748.1 - 1 9.9 10.6 6.6 7.4 10.6 2.3 1 1 0 1 1 1 0 ShK domain-like Lum_binding PF00677.17 KFM28749.1 - 2.1e-31 107.7 0.0 1e-17 63.9 0.0 2.3 2 0 0 2 2 2 2 Lumazine binding domain Cupin_8 PF13621.6 KFM28749.1 - 1.5e-18 67.4 0.0 3.2e-16 59.8 0.0 2.6 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 KFM28749.1 - 5.4e-14 52.6 0.0 5.6e-07 30.0 0.0 2.4 1 1 1 2 2 2 2 JmjC domain, hydroxylase Cupin_4 PF08007.12 KFM28749.1 - 3e-05 23.6 0.0 4.7e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.11 KFM28749.1 - 0.0019 17.9 0.0 0.012 15.3 0.0 2.2 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 KFM28749.1 - 0.019 14.6 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 Cupin SR-25 PF10500.9 KFM28749.1 - 0.11 12.1 12.9 0.18 11.4 12.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 KFM28749.1 - 0.9 7.5 16.0 1.2 7.1 16.0 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein WD40 PF00400.32 KFM28751.1 - 1.8e-24 85.6 14.6 0.00013 22.7 0.3 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM28751.1 - 7.9e-17 61.3 2.5 0.00017 21.8 0.0 4.2 4 0 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFM28751.1 - 8.9e-05 21.6 0.1 0.47 9.4 0.0 3.3 3 1 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KFM28751.1 - 0.027 14.4 0.0 1.7 8.5 0.0 2.7 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A PALB2_WD40 PF16756.5 KFM28751.1 - 0.043 12.8 2.9 0.2 10.5 0.8 2.1 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Nup160 PF11715.8 KFM28751.1 - 0.23 10.0 0.1 0.8 8.3 0.0 1.8 2 0 0 2 2 2 0 Nucleoporin Nup120/160 SIR2 PF02146.17 KFM28752.1 - 1.8e-18 67.1 0.0 1.3e-17 64.3 0.0 2.0 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 KFM28752.1 - 0.061 13.1 0.0 12 5.6 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain NAD_binding_10 PF13460.6 KFM28753.1 - 4.1e-35 121.3 1.6 7.2e-35 120.5 1.6 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KFM28753.1 - 3.3e-10 39.9 0.0 7.9e-10 38.7 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KFM28753.1 - 9.2e-09 35.1 0.0 3.3e-08 33.3 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFM28753.1 - 2.7e-06 26.6 0.0 3.9e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KFM28753.1 - 1.2e-05 24.9 0.1 2.5e-05 23.8 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 KFM28753.1 - 1.9e-05 23.9 0.1 1 8.5 0.1 3.1 3 0 0 3 3 3 3 Male sterility protein Polysacc_synt_2 PF02719.15 KFM28753.1 - 0.00017 20.8 0.0 0.00022 20.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein TrkA_N PF02254.18 KFM28753.1 - 0.00072 19.8 0.1 0.0022 18.2 0.0 1.8 1 1 0 2 2 2 1 TrkA-N domain GDP_Man_Dehyd PF16363.5 KFM28753.1 - 0.0032 16.9 0.0 0.0042 16.5 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 KFM28753.1 - 0.023 14.6 3.3 0.066 13.1 1.8 2.3 1 1 1 2 2 2 0 KR domain Sacchrp_dh_NADP PF03435.18 KFM28753.1 - 0.03 14.6 0.0 0.059 13.6 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 KFM28753.1 - 0.033 13.8 0.1 0.061 13.0 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA RmlD_sub_bind PF04321.17 KFM28753.1 - 0.054 12.6 0.1 0.092 11.8 0.1 1.5 1 1 0 1 1 1 0 RmlD substrate binding domain Pkinase PF00069.25 KFM28754.1 - 3.8e-54 183.8 0.0 1.7e-35 122.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain PAS_9 PF13426.7 KFM28754.1 - 9e-45 151.2 0.0 3.4e-21 75.4 0.0 2.3 2 0 0 2 2 2 2 PAS domain Pkinase_Tyr PF07714.17 KFM28754.1 - 2.2e-22 79.6 0.1 1.1e-16 60.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase PAS PF00989.25 KFM28754.1 - 2.6e-18 66.1 0.0 1.5e-08 34.6 0.0 2.2 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 KFM28754.1 - 1.6e-17 63.6 0.0 1.7e-08 34.6 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 KFM28754.1 - 2.7e-12 46.9 0.0 6.1e-05 23.2 0.0 2.6 2 0 0 2 2 2 2 PAS fold Kinase-like PF14531.6 KFM28754.1 - 9.2e-05 21.9 0.1 0.11 11.8 0.0 2.3 2 0 0 2 2 2 2 Kinase-like RRM_1 PF00076.22 KFM28755.1 - 4.4e-39 132.2 0.0 3.7e-16 58.7 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFM28755.1 - 1.7e-11 44.1 0.0 0.00016 21.7 0.0 3.7 2 1 1 3 3 3 3 RNA recognition motif Spo7_2_N PF15407.6 KFM28755.1 - 0.0088 15.6 0.0 6.1 6.6 0.0 3.0 3 0 0 3 3 3 1 Sporulation protein family 7 Nup35_RRM_2 PF14605.6 KFM28755.1 - 0.045 13.8 0.0 0.36 10.9 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif GRP PF07172.11 KFM28755.1 - 2.6 8.8 17.4 4.7 8.0 17.4 1.4 1 0 0 1 1 1 0 Glycine rich protein family MFS_1 PF07690.16 KFM28757.1 - 2.8e-19 69.3 45.7 3.6e-16 59.0 17.7 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 KFM28757.1 - 5.2e-06 25.6 3.4 5.2e-06 25.6 3.4 1.5 2 0 0 2 2 2 1 Sugar (and other) transporter Ribonucleas_3_3 PF14622.6 KFM28758.1 - 2.7e-15 56.7 0.0 3.9e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KFM28758.1 - 4.7e-10 40.0 0.0 8.4e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease III domain tRNA-synt_2d PF01409.20 KFM28759.1 - 4.6e-89 298.1 0.0 7.2e-89 297.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 KFM28759.1 - 3.4e-18 65.7 0.4 8.3e-18 64.4 0.0 1.9 2 0 0 2 2 2 1 PheRS DNA binding domain 3 PheRS_DBD1 PF18552.1 KFM28759.1 - 3.3e-11 42.8 0.5 7.4e-11 41.6 0.5 1.6 1 0 0 1 1 1 1 PheRS DNA binding domain 1 tRNA_synthFbeta PF17759.1 KFM28759.1 - 1.9e-07 30.7 0.0 4.3e-05 23.0 0.0 2.4 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain PheRS_DBD2 PF18554.1 KFM28759.1 - 9.5e-07 28.7 0.1 1.8e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 PheRS DNA binding domain 2 tRNA-synt_2 PF00152.20 KFM28759.1 - 7.1e-05 22.0 0.4 0.0032 16.6 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 KFM28759.1 - 0.003 17.6 0.0 0.005 16.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Ribosomal_L23 PF00276.20 KFM28760.1 - 4.5e-11 42.9 0.1 1e-10 41.8 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 Herpes_UL52 PF03121.15 KFM28761.1 - 1.1e-09 38.0 0.0 2.2e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase Abhydro_lipase PF04083.16 KFM28762.1 - 1.6e-22 78.9 0.0 2.6e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 KFM28762.1 - 5.2e-13 49.2 0.1 2.4e-12 47.0 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFM28762.1 - 8.2e-10 38.3 0.1 1.5e-08 34.2 0.1 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFM28762.1 - 0.0019 18.9 18.5 0.0051 17.4 18.5 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family CS PF04969.16 KFM28763.1 - 1.3e-16 61.3 0.0 2.6e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 CS domain TSCPD PF12637.7 KFM28764.1 - 0.08 13.2 0.3 0.13 12.5 0.3 1.3 1 0 0 1 1 1 0 TSCPD domain PI3_PI4_kinase PF00454.27 KFM28765.1 - 9.2e-10 38.7 0.0 1.2e-09 38.3 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Aminotran_1_2 PF00155.21 KFM28766.1 - 5.6e-55 187.0 0.0 6.6e-55 186.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KFM28766.1 - 4.4e-07 29.5 0.0 5.9e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KFM28766.1 - 4.1e-06 26.3 0.0 6.5e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KFM28766.1 - 0.022 13.3 0.0 0.039 12.5 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KFM28767.1 - 2.8e-50 171.5 0.0 3.5e-50 171.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II CPBP PF02517.16 KFM28767.1 - 9.1e-18 64.4 8.9 9.1e-18 64.4 8.9 2.6 2 0 0 2 2 2 1 CPBP intramembrane metalloprotease Beta_elim_lyase PF01212.21 KFM28767.1 - 2.4e-07 30.3 0.0 3.5e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KFM28767.1 - 8e-06 25.4 0.0 1.2e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KFM28767.1 - 0.22 10.0 0.0 0.33 9.5 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme OTU PF02338.19 KFM28769.1 - 4.9e-20 72.3 0.1 7.5e-20 71.7 0.1 1.2 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KFM28769.1 - 1.9e-06 27.5 0.0 0.042 13.3 0.0 2.1 2 0 0 2 2 2 2 Peptidase C65 Otubain Sin3a_C PF16879.5 KFM28769.1 - 0.042 13.6 0.0 0.056 13.2 0.0 1.1 1 0 0 1 1 1 0 C-terminal domain of Sin3a protein YorP PF09629.10 KFM28769.1 - 0.17 12.1 0.1 0.5 10.6 0.1 1.8 2 0 0 2 2 2 0 YorP protein SEC-C PF02810.15 KFM28769.1 - 0.76 9.8 12.9 1.7 8.6 12.9 1.6 1 0 0 1 1 1 0 SEC-C motif Pkinase PF00069.25 KFM28770.1 - 1.7e-77 260.4 0.0 2.1e-77 260.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM28770.1 - 1.3e-41 142.6 0.0 1.7e-41 142.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 KFM28770.1 - 8.7e-13 47.8 0.1 2e-12 46.7 0.1 1.6 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 KFM28770.1 - 4.2e-07 29.6 0.0 6.3e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KFM28770.1 - 0.0002 21.0 1.2 0.00033 20.3 1.2 1.2 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 KFM28770.1 - 0.046 12.7 0.2 0.075 12.0 0.2 1.3 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KFM28770.1 - 0.088 12.7 0.2 0.24 11.3 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family YukC PF10140.9 KFM28770.1 - 0.13 11.0 0.2 0.19 10.5 0.2 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC MMR_HSR1 PF01926.23 KFM28771.1 - 3.6e-38 130.2 0.0 7.6e-18 64.7 0.0 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 KFM28771.1 - 9.1e-17 61.0 0.0 8e-08 32.0 0.0 2.5 2 1 0 2 2 2 2 Ferrous iron transport protein B KH_dom-like PF14714.6 KFM28771.1 - 1.2e-15 57.5 0.0 2.1e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal GTP_EFTU PF00009.27 KFM28771.1 - 3.3e-07 30.0 0.0 0.55 9.7 0.0 4.6 4 1 0 4 4 4 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 KFM28771.1 - 1.3e-06 27.9 0.0 0.043 13.1 0.0 2.2 2 0 0 2 2 2 2 AIG1 family Dynamin_N PF00350.23 KFM28771.1 - 3.8e-06 27.1 0.0 0.13 12.3 0.0 3.1 3 1 1 4 4 4 2 Dynamin family RsgA_GTPase PF03193.16 KFM28771.1 - 9.7e-06 25.6 0.0 0.042 13.7 0.0 2.7 3 0 0 3 3 3 2 RsgA GTPase Arf PF00025.21 KFM28771.1 - 1.8e-05 24.2 0.0 0.021 14.3 0.0 3.1 2 1 0 2 2 2 1 ADP-ribosylation factor family Roc PF08477.13 KFM28771.1 - 4.4e-05 23.7 0.0 0.083 13.1 0.0 3.1 2 2 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KFM28771.1 - 0.00018 21.0 0.0 0.3 10.5 0.0 2.6 2 1 0 2 2 2 2 Signal recognition particle receptor beta subunit AAA_18 PF13238.6 KFM28771.1 - 0.00019 22.0 0.0 0.048 14.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KFM28771.1 - 0.00047 20.7 0.0 0.36 11.3 0.0 2.3 2 0 0 2 2 2 1 ABC transporter TniB PF05621.11 KFM28771.1 - 0.0023 17.4 0.0 0.59 9.5 0.0 3.2 3 1 0 3 3 3 1 Bacterial TniB protein AAA_28 PF13521.6 KFM28771.1 - 0.0034 17.7 0.0 1.7 8.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain Ras PF00071.22 KFM28771.1 - 0.0056 16.3 0.0 5.1 6.7 0.0 2.9 3 0 0 3 3 3 2 Ras family MeaB PF03308.16 KFM28771.1 - 0.0068 15.4 0.0 2.2 7.2 0.0 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 KFM28771.1 - 0.0091 16.4 1.3 4.2 7.7 0.1 2.6 1 1 1 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KFM28771.1 - 0.01 16.1 0.0 4.8 7.5 0.0 2.7 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 KFM28771.1 - 0.036 14.4 0.0 13 6.2 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 KFM28771.1 - 0.046 13.4 0.0 6.5 6.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KFM28771.1 - 0.086 13.0 0.0 7.8 6.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KFM28771.1 - 0.094 12.6 0.0 4.6 7.1 0.0 2.2 2 0 0 2 2 2 0 NTPase OapA_N PF08525.11 KFM28771.1 - 0.43 10.6 3.1 1.2 9.2 3.1 1.8 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif GMP_synt_C PF00958.22 KFM28773.1 - 9.2e-41 137.8 0.0 2e-40 136.7 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 KFM28773.1 - 2e-33 115.8 0.0 3e-33 115.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KFM28773.1 - 1.1e-13 51.4 0.0 1.5e-11 44.5 0.0 2.3 2 0 0 2 2 2 1 Peptidase C26 NAD_synthase PF02540.17 KFM28773.1 - 4.4e-09 35.8 0.0 0.00013 21.1 0.0 2.2 2 0 0 2 2 2 2 NAD synthase ThiI PF02568.14 KFM28773.1 - 0.0012 18.4 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.16 KFM28773.1 - 0.0016 17.3 0.0 0.0024 16.7 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase PAPS_reduct PF01507.19 KFM28773.1 - 0.053 13.5 0.0 0.088 12.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family QueC PF06508.13 KFM28773.1 - 0.069 12.6 0.0 0.25 10.8 0.0 1.9 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 KFM28773.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase Ribosomal_L2_C PF03947.18 KFM28774.1 - 4.1e-46 156.3 3.3 7.5e-46 155.4 3.3 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KFM28774.1 - 1.4e-16 60.2 0.4 2.6e-15 56.1 0.1 2.6 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain zf-C2H2_2 PF12756.7 KFM28775.1 - 5.5e-14 52.3 0.0 2.7e-12 46.9 0.0 2.6 2 1 0 2 2 2 1 C2H2 type zinc-finger (2 copies) CPSF_A PF03178.15 KFM28776.1 - 5.8e-06 25.8 0.0 9.4e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 KFM28776.1 - 0.0015 17.2 0.0 0.0042 15.8 0.0 1.6 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term FrhB_FdhB_C PF04432.13 KFM28777.1 - 3.4e-31 108.2 0.0 5.2e-31 107.6 0.0 1.3 1 0 0 1 1 1 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus FrhB_FdhB_N PF04422.13 KFM28777.1 - 5.5e-22 77.7 0.1 9.6e-22 76.9 0.1 1.4 1 0 0 1 1 1 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term TPR_1 PF00515.28 KFM28778.1 - 3.8e-17 61.3 4.6 6.7e-05 22.5 0.1 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFM28778.1 - 5.9e-16 57.3 3.3 0.0039 17.3 0.0 6.0 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFM28778.1 - 9.7e-16 56.6 11.0 0.00011 22.0 0.0 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFM28778.1 - 2.3e-13 49.6 10.4 1.9e-06 27.5 0.6 5.6 4 2 1 5 5 5 2 TPR repeat TPR_17 PF13431.6 KFM28778.1 - 1.3e-09 37.7 3.8 0.0076 16.6 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFM28778.1 - 2.8e-07 30.9 9.6 0.0058 17.1 0.9 5.5 3 1 3 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFM28778.1 - 4.1e-06 27.0 14.6 0.13 12.5 0.1 4.7 2 1 4 6 6 6 5 Tetratricopeptide repeat TPR_9 PF13371.6 KFM28778.1 - 0.00036 20.6 14.0 0.013 15.6 0.0 4.6 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFM28778.1 - 0.00042 20.1 9.3 2.7 8.2 0.0 5.8 5 1 1 6 6 5 1 Tetratricopeptide repeat TPPII_N PF12583.8 KFM28778.1 - 0.0013 19.3 0.1 0.0013 19.3 0.1 2.9 2 0 0 2 2 2 1 Tripeptidyl peptidase II N terminal TPR_14 PF13428.6 KFM28778.1 - 0.011 16.4 0.4 0.043 14.6 0.9 8.4 8 3 2 10 10 9 0 Tetratricopeptide repeat DUF4795 PF16043.5 KFM28778.1 - 0.047 13.3 0.1 0.095 12.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Phage_antiter_Q PF06323.11 KFM28778.1 - 0.11 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Phage antitermination protein Q ANAPC5 PF12862.7 KFM28778.1 - 0.18 11.9 1.2 8.1 6.6 0.1 3.0 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 5 IF2_N PF04760.15 KFM28778.1 - 0.2 11.5 0.5 11 6.0 0.1 3.2 2 1 1 3 3 3 0 Translation initiation factor IF-2, N-terminal region Myb_DNA-binding PF00249.31 KFM28778.1 - 0.2 11.9 0.0 0.46 10.7 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain TPR_6 PF13174.6 KFM28778.1 - 0.34 11.6 6.3 89 4.0 0.2 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat Methyltransf_8 PF05148.15 KFM28779.1 - 8.4e-65 218.7 0.0 1.1e-64 218.4 0.0 1.1 1 0 0 1 1 1 1 Hypothetical methyltransferase Rad10 PF03834.14 KFM28779.1 - 1.9e-33 114.9 0.0 3e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Methyltransf_11 PF08241.12 KFM28779.1 - 2.9e-09 37.4 0.1 1.7e-08 35.0 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM28779.1 - 1.6e-06 28.7 0.1 0.0009 19.9 0.0 2.7 1 1 1 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFM28779.1 - 0.00022 20.6 0.0 0.00051 19.4 0.0 1.5 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KFM28779.1 - 0.00053 19.8 0.0 0.45 10.3 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 KFM28779.1 - 0.019 14.5 0.2 4.1 6.9 0.1 2.3 1 1 1 2 2 2 0 Methyltransferase small domain Methyltransf_23 PF13489.6 KFM28779.1 - 0.085 12.7 0.0 0.53 10.1 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain PE PF00934.20 KFM28779.1 - 0.11 12.8 2.2 0.15 12.4 0.0 2.2 3 0 0 3 3 3 0 PE family TACI-CRD2 PF09305.10 KFM28779.1 - 0.13 12.3 0.1 0.27 11.3 0.1 1.5 1 0 0 1 1 1 0 TACI, cysteine-rich domain Methyltransf_12 PF08242.12 KFM28779.1 - 0.13 13.0 0.0 0.78 10.5 0.0 2.3 1 1 1 2 2 2 0 Methyltransferase domain ShK PF01549.24 KFM28780.1 - 3.5e-05 24.3 8.6 0.0001 22.8 8.6 1.9 1 0 0 1 1 1 1 ShK domain-like Glyco_transf_49 PF13896.6 KFM28780.1 - 0.11 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl-transferase for dystroglycan HTH_32 PF13565.6 KFM28780.1 - 0.12 13.0 0.0 0.36 11.5 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HATPase_c_3 PF13589.6 KFM28781.1 - 5.3e-12 45.7 0.0 9.2e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KFM28781.1 - 0.00075 20.0 0.0 0.0016 18.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Glyco_hydro2_C5 PF18565.1 KFM28781.1 - 0.012 15.4 0.3 2.9 7.8 0.0 3.3 3 0 0 3 3 3 0 Glycoside hydrolase family 2 C-terminal domain 5 Epimerase PF01370.21 KFM28782.1 - 2.1e-17 63.4 0.0 2.4e-17 63.2 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFM28782.1 - 1.6e-12 47.1 0.0 1.8e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KFM28782.1 - 5.1e-12 46.1 0.2 7e-12 45.6 0.2 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KFM28782.1 - 1.9e-10 40.4 0.0 3.4e-10 39.5 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KFM28782.1 - 1.5e-09 37.7 0.0 1.8e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KFM28782.1 - 1.5e-06 27.9 0.1 2.1e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 KFM28782.1 - 0.0018 17.4 0.0 0.003 16.7 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 KFM28782.1 - 0.011 15.7 0.4 0.06 13.2 0.4 1.9 1 1 0 1 1 1 0 KR domain adh_short PF00106.25 KFM28782.1 - 0.035 13.6 0.1 0.17 11.3 0.1 2.0 2 0 0 2 2 2 0 short chain dehydrogenase Sec1 PF00995.23 KFM28783.1 - 9.7e-101 338.8 0.0 1.2e-100 338.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF2834 PF11196.8 KFM28784.1 - 3 8.3 8.3 0.12 12.8 0.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2834) Aquarius_N PF16399.5 KFM28785.1 - 6.6e-279 927.4 0.0 8.2e-279 927.1 0.0 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_11 PF13086.6 KFM28785.1 - 5.9e-26 91.8 0.0 9.5e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 KFM28785.1 - 5.4e-23 81.7 0.0 8.5e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFM28785.1 - 2.3e-08 34.5 0.1 1.3e-07 32.0 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFM28785.1 - 6.5e-06 26.0 0.0 0.038 13.7 0.0 2.7 2 1 0 2 2 2 2 AAA domain UvrD_C_2 PF13538.6 KFM28785.1 - 3.6e-05 23.5 0.6 0.00013 21.7 0.1 2.2 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA PF00004.29 KFM28785.1 - 0.012 16.1 0.0 0.028 14.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFM28785.1 - 0.028 14.7 0.2 0.31 11.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 KFM28785.1 - 0.057 13.4 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 KFM28785.1 - 0.08 13.3 3.1 0.29 11.5 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain FUSC_2 PF13515.6 KFM28786.1 - 3.4e-09 36.9 12.0 3.4e-09 36.9 12.0 2.9 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.8 KFM28786.1 - 1.9e-07 30.3 9.5 1.9e-07 30.3 9.5 2.0 2 0 0 2 2 2 1 Aluminium activated malate transporter FUSC PF04632.12 KFM28786.1 - 4.3e-07 28.9 6.6 4.3e-07 28.9 6.6 5.2 5 1 0 5 5 5 3 Fusaric acid resistance protein family Cullin PF00888.22 KFM28789.1 - 2.1e-23 82.8 0.0 3.2e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 KFM28789.1 - 1.1e-19 70.7 0.0 2.6e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 Pkinase_Tyr PF07714.17 KFM28790.1 - 3.5e-36 124.8 0.0 9.3e-36 123.4 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM28790.1 - 1.5e-34 119.6 0.0 4.8e-34 117.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KFM28790.1 - 3.3e-06 26.2 0.0 6.7e-06 25.1 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KFM28790.1 - 0.007 15.7 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFM28790.1 - 0.077 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFM28790.1 - 0.085 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Patatin PF01734.22 KFM28791.1 - 1.6e-12 48.0 0.6 8.5e-12 45.7 0.6 2.4 1 1 0 1 1 1 1 Patatin-like phospholipase LRR_8 PF13855.6 KFM28791.1 - 1.1e-09 37.9 1.1 0.0011 18.7 0.4 2.6 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KFM28791.1 - 7.6e-09 35.7 0.9 0.048 14.1 0.0 3.5 1 1 0 3 3 3 3 Leucine Rich repeats (2 copies) Arm PF00514.23 KFM28791.1 - 0.014 15.4 0.5 0.014 15.4 0.5 2.8 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat LRR_1 PF00560.33 KFM28791.1 - 0.021 15.3 2.1 17 6.5 0.0 4.8 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_9 PF14580.6 KFM28791.1 - 0.11 12.0 0.1 0.2 11.1 0.1 1.3 1 0 0 1 1 1 0 Leucine-rich repeat Phage_TAC_4 PF08748.11 KFM28791.1 - 0.12 12.7 0.2 0.82 10.0 0.0 2.1 2 0 0 2 2 2 0 Phage tail assembly chaperone VHP PF02209.19 KFM28792.1 - 1e-14 54.3 0.3 2.2e-14 53.2 0.3 1.6 1 0 0 1 1 1 1 Villin headpiece domain Gelsolin PF00626.22 KFM28792.1 - 0.0041 17.0 0.0 0.0071 16.2 0.0 1.4 1 0 0 1 1 1 1 Gelsolin repeat HEAT_EZ PF13513.6 KFM28793.1 - 0.0028 18.1 1.8 5.5 7.6 0.2 3.8 2 1 1 3 3 3 1 HEAT-like repeat MMS19_C PF12460.8 KFM28793.1 - 0.0043 16.2 2.2 0.0067 15.6 2.2 1.3 1 0 0 1 1 1 1 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 KFM28793.1 - 0.0074 15.9 0.1 0.88 9.1 0.0 2.2 2 0 0 2 2 2 2 CLASP N terminal Adaptin_N PF01602.20 KFM28793.1 - 0.11 11.0 0.1 0.18 10.3 0.1 1.2 1 0 0 1 1 1 0 Adaptin N terminal region GTP_EFTU PF00009.27 KFM28794.1 - 1e-43 149.2 0.0 2.1e-43 148.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KFM28794.1 - 2.5e-17 63.2 0.5 4.3e-16 59.2 0.5 2.6 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KFM28794.1 - 4.1e-06 27.1 1.0 1.4e-05 25.4 0.2 2.3 2 1 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFM28794.1 - 0.0037 17.3 0.1 0.012 15.7 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF737 PF05300.11 KFM28794.1 - 0.13 12.6 2.9 0.21 11.9 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF737) G-alpha PF00503.20 KFM28794.1 - 0.24 10.5 0.0 0.41 9.8 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit PRCC PF10253.9 KFM28794.1 - 1.3 9.7 6.4 2.1 9.1 6.4 1.4 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting LCM PF04072.14 KFM28795.1 - 1.7e-07 31.4 0.1 2.5e-07 30.8 0.1 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Adeno_PIX PF03955.14 KFM28795.1 - 0.0043 17.2 0.1 0.0069 16.5 0.1 1.3 1 0 0 1 1 1 1 Adenovirus hexon-associated protein (IX) GWT1 PF06423.12 KFM28796.1 - 3.9e-21 75.7 0.3 1.7e-20 73.7 0.3 2.0 1 1 0 1 1 1 1 GWT1 His_biosynth PF00977.21 KFM28797.1 - 1.8e-45 155.2 0.0 1.7e-44 152.0 0.0 2.6 2 1 0 2 2 2 1 Histidine biosynthesis protein GATase PF00117.28 KFM28797.1 - 1.9e-14 53.9 0.0 3.1e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 KFM28797.1 - 7.7e-06 25.6 0.1 1.4e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 KFM28797.1 - 0.0013 18.5 0.1 0.0075 16.0 0.1 2.1 1 1 0 1 1 1 1 Peptidase C26 ThiG PF05690.14 KFM28797.1 - 0.17 11.2 3.3 0.14 11.5 0.7 2.1 3 0 0 3 3 3 0 Thiazole biosynthesis protein ThiG ATP_bind_1 PF03029.17 KFM28798.1 - 4.8e-85 285.2 0.0 5.5e-85 285.0 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 KFM28798.1 - 0.0038 17.0 0.0 0.0069 16.2 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_16 PF13191.6 KFM28798.1 - 0.0058 17.0 0.0 0.013 15.9 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 KFM28798.1 - 0.0088 16.6 0.0 0.015 15.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFM28798.1 - 0.015 15.0 0.0 0.041 13.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KFM28798.1 - 0.017 15.4 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KFM28798.1 - 0.034 14.5 0.0 0.055 13.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase MeaB PF03308.16 KFM28798.1 - 0.056 12.4 0.0 0.084 11.8 0.0 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_17 PF13207.6 KFM28798.1 - 0.11 13.0 0.1 0.27 11.6 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KFM28798.1 - 0.14 12.1 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 KFM28798.1 - 0.17 12.3 0.0 0.27 11.7 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 KFM28798.1 - 0.17 11.6 0.0 5.6 6.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AbiTii PF18864.1 KFM28798.1 - 0.18 12.0 0.1 0.29 11.2 0.1 1.3 1 0 0 1 1 1 0 AbiTii ABC_tran PF00005.27 KFM28798.1 - 0.21 12.1 0.0 0.36 11.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Adaptin_N PF01602.20 KFM28799.1 - 1.4e-108 363.7 0.0 7.8e-105 351.4 0.0 2.1 2 0 0 2 2 2 2 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 KFM28799.1 - 8.8e-12 45.3 0.0 1.4e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 KFM28799.1 - 4.3e-10 39.9 0.2 9e-06 25.8 0.0 2.6 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KFM28799.1 - 0.0025 18.2 15.0 0.0063 16.9 1.0 4.9 5 0 0 5 5 5 2 HEAT repeats Proteasom_PSMB PF10508.9 KFM28799.1 - 0.016 13.7 0.2 0.032 12.8 0.1 1.5 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit HEAT PF02985.22 KFM28799.1 - 2.4 8.7 6.1 17 6.0 0.3 4.7 5 1 0 5 5 5 0 HEAT repeat KTI12 PF08433.10 KFM28800.1 - 7.6e-71 238.7 0.0 8.8e-71 238.5 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 KFM28800.1 - 4.3e-11 43.1 0.0 7.9e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 KFM28800.1 - 3.2e-06 27.1 0.0 4.8e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_28 PF13521.6 KFM28800.1 - 0.004 17.4 0.7 0.037 14.3 0.7 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFM28800.1 - 0.023 15.1 2.1 0.11 12.9 2.1 2.2 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 KFM28800.1 - 0.19 12.2 0.0 0.78 10.2 0.0 1.9 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) Mito_carr PF00153.27 KFM28801.1 - 4.5e-53 177.2 0.8 9e-18 64.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DpaA_N PF16924.5 KFM28801.1 - 0.0069 16.5 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 Dipicolinate synthase subunit A N-terminal domain DUF4574 PF15141.6 KFM28801.1 - 0.027 14.4 0.1 1.6 8.7 0.1 2.2 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 COG6 PF06419.11 KFM28803.1 - 5.6e-150 500.5 0.0 6.4e-150 500.4 0.0 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Acyltransferase PF01553.21 KFM28804.1 - 2.3e-15 56.4 0.0 4.8e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase GWT1 PF06423.12 KFM28804.1 - 0.088 12.9 5.4 0.23 11.6 2.9 3.0 2 1 0 2 2 2 0 GWT1 Spo7 PF03907.13 KFM28804.1 - 0.099 12.1 0.3 4.1 6.8 0.1 2.3 2 0 0 2 2 2 0 Spo7-like protein Abhydrolase_9_N PF15420.6 KFM28804.1 - 0.35 10.8 8.4 4.5 7.2 3.0 2.8 2 1 1 3 3 3 0 Alpha/beta-hydrolase family N-terminus AAA_18 PF13238.6 KFM28805.1 - 8.6e-09 36.0 0.0 4e-08 33.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KFM28805.1 - 0.00038 20.7 0.0 0.00071 19.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 KFM28805.1 - 0.0004 20.3 0.0 0.00064 19.6 0.0 1.3 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 KFM28805.1 - 0.00056 20.1 0.0 0.00096 19.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KFM28805.1 - 0.002 17.5 0.0 0.0039 16.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Cytidylate_kin PF02224.18 KFM28805.1 - 0.0086 15.8 0.0 0.23 11.1 0.0 2.2 2 0 0 2 2 2 1 Cytidylate kinase AAA_16 PF13191.6 KFM28805.1 - 0.0093 16.4 0.1 0.019 15.4 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.10 KFM28805.1 - 0.03 13.8 0.0 0.042 13.3 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA PF00004.29 KFM28805.1 - 0.054 13.9 0.0 0.19 12.2 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 KFM28805.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase Peptidase_M20 PF01546.28 KFM28806.1 - 2.9e-27 95.7 0.0 6.4e-27 94.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.32 KFM28806.1 - 5.6e-18 65.0 11.4 0.011 16.6 0.3 7.3 6 0 0 6 6 6 5 WD domain, G-beta repeat GATase_4 PF13230.6 KFM28806.1 - 1.7e-12 46.8 0.0 8.6e-12 44.5 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 KFM28806.1 - 2.3e-12 47.2 0.0 4.9e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain M20_dimer PF07687.14 KFM28806.1 - 2.1e-07 30.8 0.0 5.6e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 Peptidase dimerisation domain PolyA_pol_arg_C PF12626.7 KFM28806.1 - 0.16 12.0 0.1 0.31 11.1 0.1 1.4 1 0 0 1 1 1 0 Polymerase A arginine-rich C-terminus Hydrolase PF00702.26 KFM28808.1 - 0.021 15.1 0.0 0.041 14.2 0.0 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD_SAK_2 PF18143.1 KFM28808.1 - 0.04 14.2 0.0 6 7.2 0.0 2.6 2 1 0 2 2 2 0 HAD domain in Swiss Army Knife RNA repair proteins Bromodomain PF00439.25 KFM28809.1 - 3.3e-35 120.0 0.0 1e-19 70.3 0.0 2.3 2 0 0 2 2 2 2 Bromodomain PHD PF00628.29 KFM28809.1 - 3.2e-24 84.6 37.9 1.8e-08 34.1 2.9 4.1 4 0 0 4 4 4 3 PHD-finger DDT PF02791.17 KFM28809.1 - 1.9e-06 28.1 0.1 3.3e-06 27.3 0.1 1.4 1 0 0 1 1 1 1 DDT domain PHD_2 PF13831.6 KFM28809.1 - 2.3e-05 23.9 11.7 6.4e-05 22.4 1.1 4.7 5 0 0 5 5 5 3 PHD-finger zf-HC5HC2H PF13771.6 KFM28809.1 - 0.023 15.0 13.1 0.36 11.1 1.7 3.6 3 0 0 3 3 3 0 PHD-like zinc-binding domain C1_1 PF00130.22 KFM28809.1 - 0.45 10.4 27.4 0.4 10.6 0.1 4.8 5 0 0 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.6 KFM28809.1 - 9.6 5.8 23.2 0.021 14.5 3.7 3.7 4 0 0 4 4 4 0 PHD/FYVE-zinc-finger like domain MtN3_slv PF03083.16 KFM28810.1 - 5.1e-25 87.3 8.8 8.4e-15 54.6 0.4 2.8 3 0 0 3 3 3 2 Sugar efflux transporter for intercellular exchange HhH-GPD PF00730.25 KFM28810.1 - 1.6e-17 63.9 0.0 2.6e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF4006 PF13179.6 KFM28810.1 - 0.055 13.4 0.9 0.15 12.0 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF4006) CoxIIa PF08113.11 KFM28810.1 - 3 7.7 5.2 0.49 10.2 0.4 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IIa family MtN3_slv PF03083.16 KFM28811.1 - 8.7e-19 67.4 10.6 2e-13 50.2 1.9 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange TrpP PF17099.5 KFM28811.1 - 4.2 7.1 11.5 1.4 8.7 1.0 3.0 2 1 2 4 4 4 0 Tryptophan transporter TrpP DUF4656 PF15551.6 KFM28812.1 - 0.023 14.2 1.1 0.023 14.2 1.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4656) ShK PF01549.24 KFM28812.1 - 0.14 12.7 7.5 0.31 11.6 7.5 1.6 1 1 0 1 1 1 0 ShK domain-like TCR PF03638.15 KFM28813.1 - 1.7e-22 79.4 52.0 9.9e-12 45.0 16.1 2.2 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain PP-binding PF00550.25 KFM28813.1 - 2.1e-13 50.4 1.3 3.3e-13 49.8 1.3 1.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 KFM28813.1 - 0.00013 22.1 0.2 0.00024 21.3 0.2 1.3 1 0 0 1 1 1 1 Acyl-carrier preSET_CXC PF18264.1 KFM28813.1 - 2.4 8.7 45.1 0.16 12.5 22.3 2.8 2 1 0 2 2 2 0 CXC domain SPA PF08616.10 KFM28814.1 - 0.0048 16.9 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Pkinase PF00069.25 KFM28816.1 - 8.9e-57 192.4 0.0 1.1e-56 192.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM28816.1 - 1.6e-27 96.5 0.0 2.1e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase NAF PF03822.14 KFM28816.1 - 5.1e-11 42.6 0.0 7.3e-05 22.9 0.0 3.3 3 0 0 3 3 3 3 NAF domain APH PF01636.23 KFM28816.1 - 0.00013 22.0 0.5 0.094 12.6 0.3 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KFM28816.1 - 0.00025 20.4 0.0 0.00042 19.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFM28816.1 - 0.003 16.4 0.0 0.0044 15.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KFM28816.1 - 0.0044 16.4 0.0 0.02 14.3 0.0 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PPR_2 PF13041.6 KFM28817.1 - 1.8e-43 146.5 0.0 2.8e-07 30.6 0.0 11.4 4 4 7 12 12 12 9 PPR repeat family PPR PF01535.20 KFM28817.1 - 3.2e-43 143.0 0.8 0.001 19.1 0.0 12.9 13 0 0 13 13 13 10 PPR repeat PPR_3 PF13812.6 KFM28817.1 - 9.2e-38 128.1 0.0 3.6e-08 33.4 0.0 8.6 7 3 3 10 10 10 7 Pentatricopeptide repeat domain PPR_1 PF12854.7 KFM28817.1 - 2.8e-35 119.7 0.0 5.4e-05 22.8 0.0 11.0 12 1 1 13 13 13 7 PPR repeat PPR_long PF17177.4 KFM28817.1 - 2.4e-27 95.7 0.0 2.8e-08 33.4 0.0 3.6 2 2 1 3 3 3 3 Pentacotripeptide-repeat region of PRORP TPR_7 PF13176.6 KFM28817.1 - 4.7e-07 29.4 0.1 2.8 8.2 0.0 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFM28817.1 - 0.00082 20.0 58.5 0.11 13.4 0.1 12.0 4 3 9 13 13 13 4 Tetratricopeptide repeat TPR_19 PF14559.6 KFM28817.1 - 0.069 13.7 0.2 0.069 13.7 0.2 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TA_inhibitor PF17574.2 KFM28817.1 - 0.19 11.8 0.4 22 5.1 0.0 3.4 2 1 1 3 3 3 0 Inhibitor of toxin/antitoxin system (Gp4.5) TPR_6 PF13174.6 KFM28817.1 - 5.4 7.9 12.7 19 6.2 0.0 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat Rgp1 PF08737.10 KFM28818.1 - 1.9e-08 33.9 0.0 0.0011 18.3 0.0 2.4 3 0 0 3 3 3 2 Rgp1 zf-HYPF PF07503.12 KFM28818.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 HypF finger Nucleopor_Nup85 PF07575.13 KFM28819.1 - 2.8e-06 26.2 0.1 4.7e-06 25.5 0.1 1.4 1 0 0 1 1 1 1 Nup85 Nucleoporin HEAT_2 PF13646.6 KFM28819.1 - 0.00012 22.4 1.7 0.00012 22.4 1.7 4.0 2 1 3 5 5 5 1 HEAT repeats HEAT_PBS PF03130.16 KFM28819.1 - 1.8 9.5 10.8 16 6.5 0.4 4.7 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat ABC_tran PF00005.27 KFM28820.1 - 2e-52 177.4 2.3 2.5e-26 92.8 0.0 3.8 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 KFM28820.1 - 3.3e-13 50.1 13.3 0.00026 20.9 0.4 4.3 2 2 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 KFM28820.1 - 3.4e-10 39.8 31.1 2.3e-09 37.1 3.4 5.0 4 1 0 4 4 4 1 ABC transporter AAA_16 PF13191.6 KFM28820.1 - 4.2e-08 33.7 0.4 0.013 15.9 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 KFM28820.1 - 1.3e-07 31.2 7.2 0.0086 15.5 0.0 4.4 5 0 0 5 5 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KFM28820.1 - 1.3e-06 28.0 0.3 0.008 15.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFM28820.1 - 6.2e-05 23.0 0.4 0.032 14.2 0.1 3.4 3 0 0 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 KFM28820.1 - 0.00014 22.1 3.8 0.066 13.5 0.0 3.5 2 2 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFM28820.1 - 0.00029 20.6 6.3 0.1 12.3 0.1 3.3 3 2 0 3 3 2 2 AAA domain MeaB PF03308.16 KFM28820.1 - 0.00035 19.7 0.7 0.31 10.0 0.3 2.6 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_15 PF13175.6 KFM28820.1 - 0.00043 20.1 3.8 0.5 10.0 3.6 3.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.6 KFM28820.1 - 0.00045 20.5 0.1 0.75 10.0 0.0 3.0 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KFM28820.1 - 0.00064 19.8 0.6 0.11 12.6 0.0 3.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 KFM28820.1 - 0.0016 18.6 0.6 0.34 11.1 0.0 3.2 3 1 0 3 3 3 1 AAA domain cobW PF02492.19 KFM28820.1 - 0.0019 17.8 0.9 1.2 8.7 0.1 2.8 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 KFM28820.1 - 0.0036 17.8 14.6 0.047 14.2 0.0 3.9 3 1 0 3 3 3 1 AAA domain NACHT PF05729.12 KFM28820.1 - 0.0054 16.7 0.3 0.78 9.6 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.6 KFM28820.1 - 0.0062 16.1 0.6 0.5 9.9 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KFM28820.1 - 0.014 15.9 0.0 5.9 7.4 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KFM28820.1 - 0.028 14.4 0.3 3.4 7.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 KFM28820.1 - 0.033 14.6 0.0 5.1 7.5 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KFM28820.1 - 0.053 13.0 0.2 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 KFM28820.1 - 0.057 13.4 1.5 3 7.9 0.0 2.8 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 KFM28820.1 - 0.081 12.6 0.2 2.7 7.7 0.0 2.8 2 0 0 2 2 2 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 KFM28820.1 - 0.089 12.2 0.1 12 5.3 0.0 3.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Dynamin_N PF00350.23 KFM28820.1 - 0.1 12.7 2.9 5 7.1 0.0 3.1 3 0 0 3 3 3 0 Dynamin family PduV-EutP PF10662.9 KFM28820.1 - 0.13 12.0 0.8 20 4.9 0.3 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Thymidylate_kin PF02223.17 KFM28820.1 - 0.14 11.8 4.3 0.59 9.8 0.0 3.2 3 0 0 3 3 3 0 Thymidylate kinase NB-ARC PF00931.22 KFM28820.1 - 0.18 11.0 2.4 5.5 6.1 0.0 3.4 2 2 0 2 2 2 0 NB-ARC domain SRP54 PF00448.22 KFM28820.1 - 0.21 11.2 4.3 0.94 9.1 0.2 3.1 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 KFM28820.1 - 0.22 11.2 10.4 0.3 10.8 0.0 3.3 4 0 0 4 4 2 0 AAA domain NTPase_1 PF03266.15 KFM28820.1 - 0.65 9.9 3.4 18 5.2 0.0 4.0 4 1 1 5 5 5 0 NTPase AAA_17 PF13207.6 KFM28820.1 - 9.2 6.7 11.3 2.6 8.5 1.0 3.6 3 1 0 3 3 3 0 AAA domain Homoserine_dh PF00742.19 KFM28822.1 - 5.1e-50 169.8 0.0 8.5e-50 169.1 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 KFM28822.1 - 9.3e-16 58.5 0.0 1.7e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF3510 PF12022.8 KFM28823.1 - 1.9e-22 79.9 0.0 4e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) COG2 PF06148.11 KFM28823.1 - 6.7e-18 65.1 0.0 2.4e-17 63.3 0.0 2.0 1 1 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF4097 PF13349.6 KFM28825.1 - 0.00081 18.8 0.8 0.0014 18.1 0.8 1.3 1 1 0 1 1 1 1 Putative adhesin Glyco_hydro_65C PF03633.15 KFM28825.1 - 0.012 15.6 0.5 0.26 11.2 0.2 2.7 3 0 0 3 3 3 0 Glycosyl hydrolase family 65, C-terminal domain NifU PF01106.17 KFM28825.1 - 0.15 12.2 0.3 6.1 7.1 0.0 2.5 2 0 0 2 2 2 0 NifU-like domain FLgD_tudor PF13861.6 KFM28825.1 - 3.1 8.1 5.8 2.7 8.3 0.8 2.8 2 1 0 2 2 2 0 FlgD Tudor-like domain PITH PF06201.13 KFM28826.1 - 2.8e-38 131.5 0.0 3.2e-38 131.3 0.0 1.0 1 0 0 1 1 1 1 PITH domain Ribosomal_L27A PF00828.19 KFM28827.1 - 1.3e-34 119.6 0.2 1.6e-34 119.3 0.2 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A GntR PF00392.21 KFM28827.1 - 0.082 12.6 0.7 0.84 9.3 0.1 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family SRP54 PF00448.22 KFM28829.1 - 1.5e-54 184.6 0.0 2.9e-54 183.7 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 KFM28829.1 - 1.8e-44 152.8 0.3 2.6e-44 152.3 0.3 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal AAA_22 PF13401.6 KFM28829.1 - 2.6e-05 24.5 0.0 9e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KFM28829.1 - 9.7e-05 22.8 3.2 0.11 13.0 0.0 3.9 3 1 1 4 4 4 1 AAA domain MeaB PF03308.16 KFM28829.1 - 0.00014 20.9 0.0 0.00041 19.4 0.0 1.7 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 KFM28829.1 - 0.00017 21.6 0.6 0.49 10.5 0.0 2.5 2 0 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 KFM28829.1 - 0.00018 22.0 0.5 0.00071 20.0 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 KFM28829.1 - 0.0013 18.5 0.1 0.003 17.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain SHD1 PF03983.12 KFM28829.1 - 0.004 16.9 0.0 0.0097 15.7 0.0 1.6 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SRP54_N PF02881.19 KFM28829.1 - 0.013 15.8 0.5 0.03 14.5 0.1 1.9 2 0 0 2 2 1 0 SRP54-type protein, helical bundle domain AAA_33 PF13671.6 KFM28829.1 - 0.014 15.6 0.1 0.11 12.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KFM28829.1 - 0.017 15.1 0.1 0.76 9.7 0.0 2.7 3 0 0 3 3 3 0 NTPase Fer4_NifH PF00142.18 KFM28829.1 - 0.031 13.7 0.1 0.056 12.9 0.1 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 KFM28829.1 - 0.063 12.4 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase MMR_HSR1 PF01926.23 KFM28829.1 - 0.11 12.6 0.6 1.3 9.1 0.6 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 KFM28829.1 - 0.14 11.8 0.0 0.38 10.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 KFM28829.1 - 0.17 11.6 0.1 0.66 9.6 0.0 2.0 2 0 0 2 2 2 0 Thymidylate kinase WD40 PF00400.32 KFM28831.1 - 3.2e-07 30.9 6.3 0.036 14.9 0.1 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM28831.1 - 0.024 14.9 0.0 26 5.2 0.0 3.5 2 2 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Complex1_LYR_2 PF13233.6 KFM28832.1 - 3.7e-07 30.8 0.0 4.4e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like DUF2852 PF11014.8 KFM28832.1 - 0.17 12.0 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) Asparaginase_2 PF01112.18 KFM28833.1 - 1.5e-23 83.3 6.5 1.8e-22 79.7 1.7 2.2 2 0 0 2 2 2 2 Asparaginase Swi3 PF07962.12 KFM28834.1 - 3e-16 59.2 0.0 4.4e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 CorA PF01544.18 KFM28835.1 - 1.5e-05 24.5 1.3 1.5e-05 24.5 1.3 2.2 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein Mce4_CUP1 PF11887.8 KFM28835.1 - 0.11 11.9 0.1 0.26 10.7 0.1 1.5 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative HTH_27 PF13463.6 KFM28835.1 - 0.15 12.6 1.2 0.23 12.0 0.3 1.9 2 0 0 2 2 2 0 Winged helix DNA-binding domain DUF2721 PF11026.8 KFM28835.1 - 0.16 11.8 2.4 0.15 12.0 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) TOC159_MAD PF11886.8 KFM28837.1 - 2.8e-55 187.1 0.0 4e-55 186.6 0.0 1.2 1 0 0 1 1 1 1 Translocase of chloroplast 159/132, membrane anchor domain AIG1 PF04548.16 KFM28837.1 - 9e-12 44.8 0.0 7.1e-11 41.8 0.0 2.0 1 1 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 KFM28837.1 - 0.0027 17.8 0.0 0.04 14.0 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KFM28837.1 - 0.01 16.2 3.3 0.15 12.4 0.2 2.4 1 1 1 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.23 KFM28837.1 - 0.025 14.6 0.1 4.9 7.2 0.0 2.5 2 1 1 3 3 3 0 Dynamin family AAA PF00004.29 KFM28837.1 - 0.038 14.4 0.0 0.089 13.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KFM28837.1 - 0.043 13.5 0.4 0.073 12.8 0.4 1.3 1 0 0 1 1 1 0 AAA domain Acyl-ACP_TE PF01643.17 KFM28838.1 - 3.2e-50 170.7 0.0 4.4e-50 170.3 0.0 1.2 1 0 0 1 1 1 1 Acyl-ACP thioesterase 4HBT PF03061.22 KFM28838.1 - 0.007 16.7 0.9 0.84 10.0 0.0 3.3 2 1 0 2 2 2 1 Thioesterase superfamily 4HBT_2 PF13279.6 KFM28838.1 - 0.0073 16.8 0.1 0.044 14.3 0.0 2.1 2 0 0 2 2 2 1 Thioesterase-like superfamily EMC3_TMCO1 PF01956.16 KFM28839.1 - 8.3e-33 113.5 0.0 1.2e-32 113.0 0.0 1.2 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like RNA_pol_Rbc25 PF08292.12 KFM28840.1 - 2.2e-21 76.5 0.0 3.2e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 KFM28840.1 - 6.7e-15 55.2 0.2 1e-14 54.6 0.2 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Drf_FH1 PF06346.12 KFM28840.1 - 0.036 13.8 2.8 0.053 13.3 2.8 1.3 1 0 0 1 1 1 0 Formin Homology Region 1 ketoacyl-synt PF00109.26 KFM28841.1 - 0 1590.0 131.2 1.2e-51 175.7 5.5 14.1 13 1 1 14 14 14 12 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KFM28841.1 - 2e-288 937.4 75.1 1.6e-29 102.4 1.6 13.4 11 1 0 11 11 11 11 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 KFM28841.1 - 1.9e-244 803.3 107.0 8.4e-35 120.3 8.5 10.2 10 0 0 10 10 9 9 KR domain PP-binding PF00550.25 KFM28841.1 - 4.8e-205 664.3 46.4 2.7e-12 46.9 0.0 18.8 18 0 0 18 18 18 18 Phosphopantetheine attachment site PS-DH PF14765.6 KFM28841.1 - 4.5e-134 446.4 92.2 1.3e-31 110.0 2.3 16.1 12 4 2 14 14 14 12 Polyketide synthase dehydratase AMP-binding PF00501.28 KFM28841.1 - 1e-84 284.6 0.1 3.8e-84 282.7 0.1 2.1 1 0 0 1 1 1 1 AMP-binding enzyme ADH_zinc_N_2 PF13602.6 KFM28841.1 - 3.6e-76 254.6 17.9 5.4e-14 53.4 0.2 7.3 6 0 0 6 6 6 6 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KFM28841.1 - 2.2e-64 215.3 29.3 2.4e-15 56.6 0.5 7.1 6 0 0 6 6 6 6 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 KFM28841.1 - 3.1e-27 95.3 1.7 0.26 11.8 0.0 9.9 10 0 0 10 10 10 7 Ketoacyl-synthetase C-terminal extension Thioesterase PF00975.20 KFM28841.1 - 7.9e-26 91.6 8.3 4.1e-14 53.2 0.0 3.7 3 0 0 3 3 3 3 Thioesterase domain AMP-binding_C PF13193.6 KFM28841.1 - 4.7e-18 65.9 0.6 3.5e-17 63.1 0.6 2.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ADH_N PF08240.12 KFM28841.1 - 2.2e-14 53.3 14.1 0.00023 21.0 0.1 5.7 5 0 0 5 5 5 3 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 KFM28841.1 - 1e-05 25.1 41.1 0.96 8.8 0.5 9.7 9 0 0 9 9 9 5 Thiolase, N-terminal domain Abhydrolase_5 PF12695.7 KFM28841.1 - 0.00098 18.9 0.0 0.0042 16.9 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family DEK_C PF08766.11 KFM28841.1 - 0.083 12.8 0.1 76 3.3 0.0 5.0 7 0 0 7 7 6 0 DEK C terminal domain PGAP1 PF07819.13 KFM28841.1 - 0.22 11.2 0.0 0.4 10.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein ESSS PF10183.9 KFM28843.1 - 0.00019 21.6 0.0 0.0002 21.5 0.0 1.2 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Fer4_8 PF13183.6 KFM28844.1 - 1.6e-10 41.3 16.6 3.9e-09 36.8 5.0 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 KFM28844.1 - 2.8e-09 37.4 4.2 4.3e-09 36.8 4.2 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer2_3 PF13085.6 KFM28844.1 - 3.2e-08 33.5 0.0 5.8e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_10 PF13237.6 KFM28844.1 - 3.4e-08 33.5 2.8 5.8e-08 32.7 2.8 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 KFM28844.1 - 0.00017 22.1 7.2 0.00063 20.3 7.5 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_18 PF13746.6 KFM28844.1 - 0.0013 18.9 0.5 0.42 10.8 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 KFM28844.1 - 0.0018 19.1 2.1 1.8 9.6 0.6 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 KFM28844.1 - 0.012 15.7 8.0 0.048 13.8 8.3 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain SF3a60_bindingd PF12108.8 KFM28844.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain Fer4_2 PF12797.7 KFM28844.1 - 0.68 10.1 11.5 5.2 7.4 0.3 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4 PF00037.27 KFM28844.1 - 1.8 8.5 13.5 3.1 7.8 0.6 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.7 KFM28844.1 - 3.1 8.0 10.0 1.7 8.9 0.3 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_3 PF12798.7 KFM28844.1 - 8.3 7.6 16.3 11 7.2 1.1 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer2_3 PF13085.6 KFM28845.1 - 4.4e-31 107.1 0.0 6.9e-31 106.5 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 KFM28845.1 - 9.2e-09 35.7 4.2 9.2e-09 35.7 4.2 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KFM28845.1 - 1.4e-08 35.1 5.7 1.4e-08 35.1 5.7 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 KFM28845.1 - 1.2e-07 31.8 2.7 1.2e-07 31.8 2.7 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 KFM28845.1 - 0.001 19.0 0.3 0.001 19.0 0.3 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 KFM28845.1 - 0.0011 19.6 7.1 0.0011 19.6 7.1 2.6 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.6 KFM28845.1 - 0.02 15.1 3.8 0.79 9.9 0.1 2.8 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 KFM28845.1 - 0.038 14.9 6.2 3.1 8.8 0.6 2.9 3 0 0 3 3 3 0 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 KFM28845.1 - 0.14 12.3 12.3 0.066 13.4 7.7 2.5 2 1 0 2 2 2 0 4Fe-4S dicluster domain SF3a60_bindingd PF12108.8 KFM28845.1 - 0.18 11.7 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain Complex1_LYR PF05347.15 KFM28846.1 - 5e-12 45.7 0.3 8.5e-12 44.9 0.3 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) EFP_N PF08207.12 KFM28847.1 - 1.4e-26 92.3 0.0 3.8e-26 90.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Elong-fact-P_C PF09285.11 KFM28847.1 - 2.3e-26 91.3 0.4 6.7e-26 89.8 0.2 1.9 2 0 0 2 2 2 1 Elongation factor P, C-terminal EFP PF01132.20 KFM28847.1 - 1.6e-15 56.8 0.1 2.8e-15 56.1 0.1 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain PDT PF00800.18 KFM28848.1 - 9.2e-56 188.6 0.0 1.1e-55 188.3 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 KFM28848.1 - 9.2e-05 22.1 0.0 0.00019 21.2 0.0 1.6 1 0 0 1 1 1 1 ACT domain Na_H_Exchanger PF00999.21 KFM28849.1 - 1.6e-36 125.9 44.3 9.6e-29 100.3 27.1 3.0 2 1 1 3 3 3 2 Sodium/hydrogen exchanger family TrkA_N PF02254.18 KFM28849.1 - 3e-20 72.6 2.0 7.2e-20 71.4 0.0 2.6 3 0 0 3 3 3 1 TrkA-N domain DUF5089 PF17002.5 KFM28849.1 - 0.13 12.2 0.2 0.22 11.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5089) Gp_dh_N PF00044.24 KFM28849.1 - 0.15 12.4 0.1 0.49 10.8 0.0 1.9 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain UPF0172 PF03665.13 KFM28850.1 - 3.8e-40 138.0 0.0 6.1e-40 137.3 0.0 1.3 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0172) PHO4 PF01384.20 KFM28851.1 - 2.2e-102 342.6 21.2 2.9e-102 342.2 21.2 1.2 1 0 0 1 1 1 1 Phosphate transporter family Pkinase PF00069.25 KFM28854.1 - 1e-43 149.6 0.0 1.5e-43 149.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM28854.1 - 5.1e-17 62.0 0.0 1.1e-16 60.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Se-cys_synth_N PF12390.8 KFM28854.1 - 6.8 7.0 6.8 1.2 9.5 0.3 2.8 3 0 0 3 3 3 0 Selenocysteine synthase N terminal AP2 PF00847.20 KFM28855.1 - 6.4e-19 67.9 8.6 2e-10 40.8 2.1 2.5 2 0 0 2 2 2 2 AP2 domain P5CR_dimer PF14748.6 KFM28856.1 - 2.3e-40 137.0 3.0 3.3e-40 136.5 2.0 1.8 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KFM28856.1 - 1.6e-18 67.1 0.3 3.6e-18 65.9 0.3 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KFM28856.1 - 0.00055 20.1 0.1 0.00096 19.3 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 KFM28856.1 - 0.0094 15.6 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 KFM28856.1 - 0.014 15.3 1.6 0.22 11.5 1.9 2.4 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus CoA_binding PF02629.19 KFM28856.1 - 0.023 15.3 2.3 0.11 13.3 0.4 2.4 2 1 0 2 2 2 0 CoA binding domain PDH PF02153.17 KFM28856.1 - 0.026 13.5 0.5 0.044 12.8 0.5 1.5 1 1 0 1 1 1 0 Prephenate dehydrogenase Shikimate_DH PF01488.20 KFM28856.1 - 0.11 12.6 0.2 0.32 11.1 0.2 1.9 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase TFIIB PF00382.19 KFM28857.1 - 0.00037 20.5 0.3 0.023 14.7 0.6 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat SRP68 PF16969.5 KFM28858.1 - 3.8e-98 329.9 4.2 1.2e-75 255.7 0.4 2.0 1 1 1 2 2 2 2 RNA-binding signal recognition particle 68 AAA PF00004.29 KFM28859.1 - 1.2e-91 304.0 0.0 9.4e-47 158.7 0.0 3.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFM28859.1 - 4.6e-26 90.4 7.8 1.1e-13 50.8 1.8 2.9 3 0 0 3 3 2 2 AAA+ lid domain CDC48_N PF02359.18 KFM28859.1 - 6.1e-23 80.8 0.6 3e-22 78.6 0.2 2.5 2 1 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.17 KFM28859.1 - 3.6e-11 42.7 0.0 7.5e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_2 PF07724.14 KFM28859.1 - 8.7e-10 39.0 0.0 5.4e-06 26.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KFM28859.1 - 2.9e-09 36.9 0.1 2.1e-05 24.3 0.0 3.1 3 1 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KFM28859.1 - 1.4e-08 35.3 0.2 0.00027 21.3 0.1 4.1 2 2 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KFM28859.1 - 2.5e-07 31.0 0.3 0.018 15.3 0.1 4.5 3 2 1 4 4 3 1 AAA domain AAA_33 PF13671.6 KFM28859.1 - 4.1e-07 30.3 0.0 7.2e-05 23.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KFM28859.1 - 7.6e-07 29.2 0.0 0.0042 17.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain FHA PF00498.26 KFM28859.1 - 1.9e-06 28.2 0.0 4.6e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 FHA domain Vps4_C PF09336.10 KFM28859.1 - 2.2e-06 27.6 0.1 0.00011 22.1 0.0 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_5 PF07728.14 KFM28859.1 - 2.9e-06 27.3 0.1 0.00011 22.2 0.0 3.1 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 KFM28859.1 - 4.7e-05 23.2 0.0 0.0047 16.7 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 KFM28859.1 - 8.1e-05 23.2 0.0 0.02 15.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 KFM28859.1 - 9e-05 21.8 0.0 0.0017 17.6 0.0 2.4 2 0 0 2 2 2 1 TIP49 P-loop domain UFD1 PF03152.14 KFM28859.1 - 0.00054 19.5 0.0 0.00094 18.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Zeta_toxin PF06414.12 KFM28859.1 - 0.0012 18.1 0.0 0.17 11.2 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin RNA_helicase PF00910.22 KFM28859.1 - 0.0022 18.4 0.0 0.75 10.2 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.21 KFM28859.1 - 0.0034 16.8 0.2 0.058 12.8 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KFM28859.1 - 0.0065 16.2 0.0 0.18 11.5 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein Cytidylate_kin2 PF13189.6 KFM28859.1 - 0.0083 16.3 0.0 0.83 9.8 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase-like family NACHT PF05729.12 KFM28859.1 - 0.0094 15.9 0.9 5.6 6.9 0.0 3.4 3 1 1 4 4 4 0 NACHT domain AAA_28 PF13521.6 KFM28859.1 - 0.01 16.1 0.0 1.4 9.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.6 KFM28859.1 - 0.011 16.2 0.0 0.28 11.6 0.0 2.9 3 0 0 3 3 2 0 AAA domain TsaE PF02367.17 KFM28859.1 - 0.012 15.7 0.0 1.1 9.3 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 KFM28859.1 - 0.013 15.4 0.3 0.6 10.0 0.1 3.2 2 2 0 2 2 2 0 ATPase domain predominantly from Archaea ResIII PF04851.15 KFM28859.1 - 0.019 15.0 0.0 0.12 12.4 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ABC_tran PF00005.27 KFM28859.1 - 0.02 15.4 0.0 6.7 7.2 0.0 2.8 2 1 0 2 2 2 0 ABC transporter NB-ARC PF00931.22 KFM28859.1 - 0.032 13.4 0.0 2.4 7.3 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Sigma54_activat PF00158.26 KFM28859.1 - 0.037 13.7 0.0 0.81 9.4 0.0 2.8 2 1 0 2 2 2 0 Sigma-54 interaction domain ATPase PF06745.13 KFM28859.1 - 0.038 13.3 0.8 8.4 5.7 0.1 2.7 3 0 0 3 3 3 0 KaiC AAA_24 PF13479.6 KFM28859.1 - 0.051 13.3 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KFM28859.1 - 0.057 12.9 0.0 6.5 6.1 0.1 2.6 2 0 0 2 2 2 0 PhoH-like protein SKI PF01202.22 KFM28859.1 - 0.066 13.3 0.0 14 5.8 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase NTPase_1 PF03266.15 KFM28859.1 - 0.086 12.7 0.4 83 3.0 0.0 4.0 3 1 0 4 4 4 0 NTPase DUF2075 PF09848.9 KFM28859.1 - 0.089 12.0 0.0 1.1 8.5 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.6 KFM28859.1 - 0.1 12.7 0.0 0.55 10.3 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 KFM28859.1 - 0.15 11.7 0.4 6.2 6.3 0.0 2.9 2 1 0 3 3 2 0 AAA domain AAA_3 PF07726.11 KFM28859.1 - 0.15 11.9 0.0 4.3 7.2 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 KFM28859.1 - 0.21 10.7 0.2 1.7 7.6 0.0 2.0 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 KFM28859.1 - 0.22 11.0 0.0 1.6 8.2 0.0 2.4 2 1 0 2 2 2 0 P-loop containing dynein motor region DUF3110 PF11360.8 KFM28860.1 - 2.1e-19 69.5 0.0 3.2e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3110) DUF819 PF05684.12 KFM28862.1 - 2.5e-41 142.0 15.2 1e-27 97.2 1.9 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF819) CAF1C_H4-bd PF12265.8 KFM28862.1 - 1e-16 60.9 0.2 2.7e-16 59.6 0.2 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KFM28862.1 - 1.2e-16 60.8 11.2 0.0016 19.2 0.5 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Gln-synt_C PF00120.24 KFM28863.1 - 1.2e-15 57.3 0.0 2.9e-14 52.8 0.0 2.0 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KFM28863.1 - 1.8e-08 34.0 0.0 3.4e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Malic_M PF03949.15 KFM28864.1 - 9.6e-52 175.8 0.0 1.3e-51 175.4 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KFM28864.1 - 4.3e-39 134.2 0.0 7.8e-39 133.3 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Suv3_C_1 PF18147.1 KFM28866.1 - 1.1e-11 44.4 0.2 2.6e-11 43.2 0.2 1.7 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 SUV3_C PF12513.8 KFM28866.1 - 2.1e-11 43.6 0.0 6.5e-11 42.0 0.0 1.9 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 KFM28866.1 - 7.6e-11 42.3 0.1 1.5e-10 41.4 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T2SSE PF00437.20 KFM28866.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein IMS PF00817.20 KFM28868.1 - 4.5e-43 146.8 0.0 7e-43 146.2 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KFM28868.1 - 6.8e-16 59.0 0.0 1.3e-15 58.1 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain Cdd1 PF11731.8 KFM28868.1 - 0.00037 20.7 0.0 0.00083 19.6 0.0 1.5 1 0 0 1 1 1 1 Pathogenicity locus IMS_HHH PF11798.8 KFM28868.1 - 0.0005 20.2 0.2 0.0022 18.2 0.0 2.2 2 0 0 2 2 2 1 IMS family HHH motif HHH_5 PF14520.6 KFM28868.1 - 0.0071 16.9 0.0 0.019 15.6 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 KFM28868.1 - 0.008 16.0 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda mCpol PF18182.1 KFM28868.1 - 0.022 15.1 0.0 0.043 14.2 0.0 1.5 1 0 0 1 1 1 0 minimal CRISPR polymerase domain DUF1805 PF08827.11 KFM28868.1 - 0.056 13.8 0.1 0.19 12.1 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) Cytochrom_B561 PF03188.16 KFM28869.1 - 2e-17 63.6 3.3 2.3e-17 63.4 3.3 1.0 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 PIGA PF08288.12 KFM28870.1 - 2.2e-23 82.7 0.3 5.2e-23 81.4 0.3 1.6 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.20 KFM28870.1 - 4.3e-21 75.2 0.0 6.3e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KFM28870.1 - 4.8e-21 75.6 0.8 1.5e-20 74.0 0.1 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KFM28870.1 - 8.2e-17 61.7 0.2 1.5e-16 60.9 0.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KFM28870.1 - 0.01 16.2 0.1 0.032 14.6 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferases group 1 Sad1_UNC PF07738.13 KFM28871.1 - 2e-12 47.2 0.0 3.2e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Uso1_p115_C PF04871.13 KFM28871.1 - 0.053 13.9 2.5 0.077 13.4 2.5 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region HisKA_3 PF07730.13 KFM28871.1 - 0.068 13.7 2.7 0.15 12.6 2.7 1.5 1 0 0 1 1 1 0 Histidine kinase APG6_N PF17675.1 KFM28871.1 - 0.35 11.4 3.0 0.61 10.6 3.0 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region MT-A70 PF05063.14 KFM28872.1 - 2e-39 135.3 0.0 2.5e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 MT-A70 TIC20 PF16166.5 KFM28873.1 - 4.7e-20 72.1 9.3 5e-20 72.0 9.3 1.1 1 0 0 1 1 1 1 Chloroplast import apparatus Tic20-like DUF4381 PF14316.6 KFM28873.1 - 2.2 8.5 6.1 0.54 10.5 2.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) TPR_16 PF13432.6 KFM28874.1 - 0.0088 16.7 8.2 0.036 14.7 0.7 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC4_WD40 PF12894.7 KFM28874.1 - 0.17 12.2 0.0 15 6.0 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain RNA_pol_Rpb2_1 PF04563.15 KFM28875.1 - 8.7e-39 133.1 0.0 1.1e-38 132.8 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KFM28875.1 - 0.00054 19.6 0.0 0.017 14.8 0.0 2.4 1 1 1 2 2 2 1 RNA polymerase Rpb2, domain 2 HBS1_N PF08938.10 KFM28875.1 - 0.031 14.6 0.2 0.062 13.6 0.2 1.4 1 0 0 1 1 1 0 HBS1 N-terminus DUF321 PF03778.13 KFM28875.1 - 2.8 7.7 4.5 2.8 7.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF321) PIP5K PF01504.18 KFM28876.1 - 3.3e-37 128.2 0.0 1.9e-29 102.8 0.0 2.0 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase AICARFT_IMPCHas PF01808.18 KFM28877.1 - 6.6e-109 363.9 0.0 8.1e-109 363.6 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 KFM28877.1 - 2e-22 79.2 0.0 4.2e-22 78.2 0.0 1.6 1 0 0 1 1 1 1 MGS-like domain LysR_substrate PF03466.20 KFM28877.1 - 0.048 13.0 0.0 0.092 12.1 0.0 1.4 1 0 0 1 1 1 0 LysR substrate binding domain Phosphonate-bd PF12974.7 KFM28877.1 - 0.081 12.5 0.1 0.35 10.4 0.0 1.9 2 0 0 2 2 2 0 ABC transporter, phosphonate, periplasmic substrate-binding protein Tim17 PF02466.19 KFM28878.1 - 2.7e-22 79.2 0.4 4e-22 78.7 0.4 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family PGK PF00162.19 KFM28880.1 - 3.6e-162 539.6 0.1 4.7e-162 539.2 0.1 1.1 1 0 0 1 1 1 1 Phosphoglycerate kinase Hydrolase PF00702.26 KFM28880.1 - 0.07 13.4 0.2 1.1 9.5 0.0 2.5 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase NOA36 PF06524.12 KFM28880.1 - 1.4 8.2 6.7 2.4 7.4 6.7 1.2 1 0 0 1 1 1 0 NOA36 protein Acetyltransf_1 PF00583.25 KFM28881.1 - 5.5e-16 58.9 0.1 6.6e-16 58.6 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFM28881.1 - 5.6e-11 42.7 0.1 8.1e-11 42.2 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFM28881.1 - 1.7e-08 34.4 0.0 3e-08 33.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFM28881.1 - 1.8e-05 24.6 0.0 3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KFM28881.1 - 8.4e-05 23.3 0.0 0.00012 22.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KFM28881.1 - 0.00017 21.7 0.0 0.034 14.2 0.0 2.1 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KFM28881.1 - 0.0021 18.2 0.0 0.0043 17.2 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KFM28881.1 - 0.0082 16.3 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.6 KFM28881.1 - 0.021 14.5 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain L51_S25_CI-B8 PF05047.16 KFM28882.1 - 1.7e-13 50.3 0.0 2.3e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain RNA_pol_Rpb4 PF03874.16 KFM28883.1 - 0.00045 20.6 0.4 0.23 11.8 0.0 2.2 1 1 1 2 2 2 2 RNA polymerase Rpb4 Cro PF09048.10 KFM28883.1 - 0.061 13.4 0.0 0.17 12.0 0.0 1.7 2 0 0 2 2 2 0 Cro Sld5 PF05916.11 KFM28884.1 - 3.4e-07 30.7 0.0 5.8e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein Amidohydro_1 PF01979.20 KFM28885.1 - 3.4e-31 108.8 3.8 4.3e-31 108.5 3.8 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFM28885.1 - 2.8e-13 50.2 13.8 2.8e-05 23.8 5.9 3.2 1 1 0 1 1 1 1 Amidohydrolase family SNF5 PF04855.12 KFM28886.1 - 1.3e-24 87.3 0.0 5.8e-14 52.5 0.0 2.0 1 1 1 2 2 2 2 SNF5 / SMARCB1 / INI1 Bap31 PF05529.12 KFM28887.1 - 2.1e-05 24.4 0.2 3.1e-05 23.8 0.2 1.2 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Sulfotransfer_3 PF13469.6 KFM28889.1 - 1.5e-35 123.5 0.0 4.1e-35 122.1 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 KFM28889.1 - 1.4e-08 34.6 0.0 2.3e-08 33.9 0.0 1.4 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_4 PF17784.1 KFM28889.1 - 0.0052 16.6 0.0 0.48 10.2 0.0 2.4 2 0 0 2 2 2 2 Sulfotransferase domain Rep_fac_C PF08542.11 KFM28891.1 - 3.2e-16 59.5 0.0 9.5e-16 58.0 0.0 1.9 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA PF00004.29 KFM28891.1 - 1.7e-15 57.6 0.0 2.5e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KFM28891.1 - 1.8e-12 47.6 0.0 1.3e-10 41.6 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain DNA_pol3_delta2 PF13177.6 KFM28891.1 - 9.6e-12 45.0 0.0 8.8e-09 35.3 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA_11 PF13086.6 KFM28891.1 - 1e-05 25.5 0.1 3.4e-05 23.8 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 KFM28891.1 - 1.3e-05 25.2 0.0 0.0003 20.8 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KFM28891.1 - 3.2e-05 24.4 0.1 0.0002 21.8 0.1 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KFM28891.1 - 5.3e-05 23.2 1.2 0.0034 17.4 0.2 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KFM28891.1 - 0.00016 21.4 0.1 0.00049 19.9 0.1 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KFM28891.1 - 0.00027 21.2 0.4 0.0087 16.3 0.2 2.7 2 1 0 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 KFM28891.1 - 0.00053 20.3 0.0 0.0011 19.2 0.0 1.6 1 0 0 1 1 1 1 AAA C-terminal domain DUF815 PF05673.13 KFM28891.1 - 0.0008 18.6 0.0 0.0011 18.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ResIII PF04851.15 KFM28891.1 - 0.00081 19.4 0.0 0.047 13.7 0.0 2.1 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_24 PF13479.6 KFM28891.1 - 0.00085 19.1 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFM28891.1 - 0.004 17.5 0.2 0.058 13.7 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 KFM28891.1 - 0.0064 17.0 0.0 0.011 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 KFM28891.1 - 0.0083 16.0 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KFM28891.1 - 0.016 14.7 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 KFM28891.1 - 0.018 14.8 0.0 0.037 13.8 0.0 1.5 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 KFM28891.1 - 0.023 14.4 0.0 0.082 12.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KFM28891.1 - 0.025 14.2 0.0 0.13 11.8 0.0 2.2 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 KFM28891.1 - 0.029 13.8 0.0 0.4 10.0 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ARTD15_N PF18084.1 KFM28891.1 - 0.037 14.3 0.0 0.11 12.8 0.0 1.7 2 0 0 2 2 1 0 ARTD15 N-terminal domain TniB PF05621.11 KFM28891.1 - 0.041 13.3 0.0 0.56 9.6 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein FtsK_SpoIIIE PF01580.18 KFM28891.1 - 0.05 12.9 0.0 0.15 11.4 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_28 PF13521.6 KFM28891.1 - 0.052 13.8 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain KfrA_N PF11740.8 KFM28891.1 - 0.062 14.0 0.0 0.23 12.2 0.0 1.8 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term ATPase_2 PF01637.18 KFM28891.1 - 0.071 13.0 0.0 0.097 12.6 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 KFM28891.1 - 0.085 12.6 0.0 4.4 7.0 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain cobW PF02492.19 KFM28891.1 - 0.085 12.4 0.0 0.18 11.3 0.0 1.5 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain TIP49 PF06068.13 KFM28891.1 - 0.17 11.0 0.0 0.34 10.1 0.0 1.4 2 0 0 2 2 2 0 TIP49 P-loop domain RNA_helicase PF00910.22 KFM28891.1 - 0.19 12.2 0.0 0.31 11.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Pkinase PF00069.25 KFM28892.1 - 3.2e-50 171.0 0.0 6.3e-50 170.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM28892.1 - 1.6e-27 96.4 0.0 3.6e-27 95.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM28892.1 - 0.00029 20.3 0.0 0.00044 19.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KFM28892.1 - 0.00049 19.7 0.1 0.00086 19.0 0.1 1.3 1 0 0 1 1 1 1 RIO1 family cNMP_binding PF00027.29 KFM28892.1 - 0.0034 17.4 0.0 0.022 14.8 0.0 2.3 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain APH PF01636.23 KFM28892.1 - 0.081 12.8 0.0 0.081 12.8 0.0 2.4 3 0 0 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 KFM28892.1 - 0.093 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_M20 PF01546.28 KFM28893.1 - 4.9e-32 111.3 1.8 6.6e-32 110.9 1.8 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KFM28893.1 - 1.6e-06 28.0 0.1 2.7e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Proteasome PF00227.26 KFM28894.1 - 6.9e-62 208.3 0.0 9.8e-62 207.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KFM28894.1 - 2.9e-10 39.6 1.4 4.8e-10 38.9 0.1 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature SNF5 PF04855.12 KFM28895.1 - 0.00038 20.3 0.0 0.0005 19.9 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Synaptobrevin PF00957.21 KFM28896.1 - 7e-15 54.6 0.2 1.1e-14 54.0 0.2 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KFM28896.1 - 2.1e-08 34.1 0.0 3.3e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Transferase PF02458.15 KFM28897.1 - 0.02 13.5 0.0 0.53 8.9 0.0 2.0 2 0 0 2 2 2 0 Transferase family TruD PF01142.18 KFM28898.1 - 5.1e-63 213.3 0.0 2.8e-56 191.1 0.0 3.2 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Smr PF01713.21 KFM28899.1 - 0.23 11.8 1.4 4.5 7.7 0.0 3.5 4 0 0 4 4 4 0 Smr domain HECT PF00632.25 KFM28900.1 - 1.9e-66 224.6 0.0 6.9e-64 216.2 0.0 2.1 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) LCIB_C_CA PF18599.1 KFM28901.1 - 8.9e-79 263.9 0.0 1.1e-78 263.5 0.0 1.1 1 0 0 1 1 1 1 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Actin PF00022.19 KFM28902.1 - 2.1e-65 221.0 0.0 2.4e-64 217.5 0.0 1.9 1 1 0 1 1 1 1 Actin UCH PF00443.29 KFM28903.1 - 3.8e-75 252.7 0.0 4.9e-75 252.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFM28903.1 - 1.3e-17 64.4 0.0 3.1e-09 36.9 0.0 3.3 4 0 0 4 4 4 3 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 KFM28903.1 - 2.9e-13 50.2 0.0 5.4e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 DUSP domain zf-ribbon_3 PF13248.6 KFM28903.1 - 0.072 12.5 2.4 0.69 9.4 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf_UBZ PF18439.1 KFM28903.1 - 0.082 12.5 1.7 3 7.5 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger LppX_LprAFG PF07161.13 KFM28903.1 - 0.18 11.6 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 LppX_LprAFG lipoprotein PhnA_Zn_Ribbon PF08274.12 KFM28903.1 - 0.23 11.5 1.0 1.9 8.5 0.2 2.7 3 0 0 3 3 3 0 PhnA Zinc-Ribbon Peptidase_C1 PF00112.23 KFM28904.1 - 1.5e-60 205.0 0.1 2.6e-60 204.2 0.1 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 KFM28904.1 - 7.1e-16 58.4 1.1 1.1e-15 57.8 1.1 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Mur_ligase_M PF08245.12 KFM28905.1 - 5.5e-06 26.5 0.0 8.8e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Mur ligase middle domain CTP_synth_N PF06418.14 KFM28906.1 - 2.6e-127 423.6 0.0 3.4e-127 423.3 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 KFM28906.1 - 8.6e-52 175.7 0.0 1.3e-51 175.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CbiA PF01656.23 KFM28906.1 - 0.0085 16.1 0.0 0.022 14.8 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Peptidase_C26 PF07722.13 KFM28906.1 - 0.054 13.2 0.2 0.37 10.5 0.2 2.3 1 1 0 1 1 1 0 Peptidase C26 Pkinase PF00069.25 KFM28908.1 - 1.8e-64 217.6 0.0 2.1e-64 217.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM28908.1 - 1.7e-47 161.9 0.0 2e-47 161.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFM28908.1 - 2e-07 30.6 0.1 4.3e-05 23.0 0.1 2.4 2 1 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KFM28908.1 - 1.9e-06 27.0 0.0 2.6e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KFM28908.1 - 0.00012 21.1 0.0 0.0029 16.6 0.0 2.1 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KFM28908.1 - 0.00025 21.0 0.0 0.2 11.5 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family ABC1 PF03109.16 KFM28908.1 - 0.0024 18.0 0.0 0.0044 17.2 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Kdo PF06293.14 KFM28908.1 - 0.16 11.3 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MMgT PF10270.9 KFM28909.1 - 0.0037 17.6 0.0 0.0045 17.3 0.0 1.2 1 0 0 1 1 1 1 Membrane magnesium transporter COX14 PF14880.6 KFM28909.1 - 0.47 10.3 0.1 0.47 10.3 0.1 2.0 3 0 0 3 3 3 0 Cytochrome oxidase c assembly SNO PF01174.19 KFM28911.1 - 1.5e-46 158.6 0.0 2e-46 158.2 0.0 1.1 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 KFM28911.1 - 2.1e-07 30.8 0.0 3.2e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain BPL_N PF09825.9 KFM28911.1 - 0.00025 20.2 0.0 0.00036 19.7 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal Peptidase_S51 PF03575.17 KFM28911.1 - 0.0026 17.5 0.0 0.0038 16.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 GATase PF00117.28 KFM28911.1 - 0.0071 16.1 0.0 0.071 12.9 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 KFM28911.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family UDPG_MGDP_dh_N PF03721.14 KFM28912.1 - 1.4e-53 181.3 0.0 2.3e-53 180.6 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 KFM28912.1 - 2.2e-35 121.3 0.1 4.5e-34 117.0 0.0 2.4 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 KFM28912.1 - 3.2e-32 110.6 0.0 6.5e-32 109.6 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_2 PF03446.15 KFM28912.1 - 0.077 13.2 0.1 0.25 11.5 0.1 1.9 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.14 KFM28913.1 - 4.3e-56 189.5 0.0 7.3e-56 188.7 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 KFM28913.1 - 4e-33 114.0 0.0 3.7e-32 110.9 0.0 2.2 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 KFM28913.1 - 8.9e-32 109.2 0.1 2e-31 108.1 0.1 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_2 PF03446.15 KFM28913.1 - 0.061 13.5 0.0 0.28 11.3 0.0 2.0 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase AAA_12 PF13087.6 KFM28914.1 - 2.2e-58 197.2 0.0 3.2e-58 196.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain UPF1_Zn_bind PF09416.10 KFM28914.1 - 1.9e-56 190.2 0.0 3.1e-56 189.6 0.0 1.3 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) AAA_11 PF13086.6 KFM28914.1 - 6.6e-48 163.8 1.7 8.3e-27 94.6 0.1 2.2 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 KFM28914.1 - 6.2e-27 93.7 0.0 1.4e-26 92.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 KFM28914.1 - 5.1e-15 55.7 4.2 5.2e-14 52.4 4.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFM28914.1 - 7.2e-11 42.6 0.1 5.7e-10 39.7 0.1 2.3 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.9 KFM28914.1 - 0.00031 20.1 0.3 0.014 14.7 0.0 2.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 KFM28914.1 - 0.00042 20.2 0.2 0.00083 19.2 0.2 1.5 1 0 0 1 1 1 1 Helicase AAA_16 PF13191.6 KFM28914.1 - 0.0016 18.9 1.1 0.0051 17.2 1.1 2.0 1 0 0 1 1 1 1 AAA ATPase domain ResIII PF04851.15 KFM28914.1 - 0.0023 18.0 0.0 0.0036 17.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 KFM28914.1 - 0.0023 17.5 0.1 0.072 12.6 0.1 2.1 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain NACHT PF05729.12 KFM28914.1 - 0.028 14.3 0.0 0.068 13.1 0.0 1.7 1 0 0 1 1 1 0 NACHT domain ATPase PF06745.13 KFM28914.1 - 0.042 13.2 0.0 0.07 12.5 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.6 KFM28914.1 - 0.042 13.4 0.2 0.084 12.4 0.2 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KFM28914.1 - 0.056 13.7 0.1 0.15 12.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain PIF1 PF05970.14 KFM28914.1 - 0.06 12.5 0.1 8.1 5.5 0.1 2.1 1 1 1 2 2 2 0 PIF1-like helicase Ribosomal_S13_N PF08069.12 KFM28914.1 - 0.079 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain UvrD_C_2 PF13538.6 KFM28914.1 - 0.12 12.2 0.0 0.34 10.8 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Heme_oxygenase PF01126.20 KFM28914.1 - 0.16 11.7 0.1 0.28 10.9 0.1 1.2 1 0 0 1 1 1 0 Heme oxygenase PhoH PF02562.16 KFM28914.1 - 0.18 11.3 0.0 0.36 10.3 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Amidohydro_1 PF01979.20 KFM28915.1 - 2.7e-10 40.1 0.0 3.4e-10 39.8 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.14 KFM28915.1 - 2.3e-05 24.3 0.0 4.3e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase TolA PF06519.11 KFM28915.1 - 0.18 12.0 0.0 0.32 11.2 0.0 1.3 1 0 0 1 1 1 0 TolA C-terminal PCNA_N PF00705.18 KFM28916.1 - 2.6e-58 195.2 1.6 4.1e-58 194.6 1.6 1.3 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 KFM28916.1 - 3.6e-51 172.6 0.0 7.5e-51 171.6 0.0 1.5 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 KFM28916.1 - 1.5e-06 27.9 0.0 1.8e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 KFM28916.1 - 0.0001 21.4 0.2 0.00038 19.6 0.2 1.8 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.12 KFM28916.1 - 0.056 12.6 0.0 2.8 7.0 0.0 2.2 2 0 0 2 2 2 0 Hus1-like protein PP2C PF00481.21 KFM28917.1 - 8.5e-40 137.0 0.0 1.2e-39 136.5 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KFM28917.1 - 1.6e-07 31.5 0.1 0.00012 22.1 0.0 2.1 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KFM28917.1 - 0.00015 21.5 0.0 0.00029 20.5 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C ABC2_membrane PF01061.24 KFM28918.1 - 7e-30 104.0 20.5 7e-30 104.0 20.5 1.9 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 KFM28918.1 - 3.8e-23 82.5 0.0 5.5e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KFM28918.1 - 1.1e-06 28.7 0.0 0.0084 16.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KFM28918.1 - 5.9e-05 22.7 0.1 0.00016 21.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFM28918.1 - 7.5e-05 23.2 0.0 0.00015 22.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain ABC2_membrane_3 PF12698.7 KFM28918.1 - 0.00038 19.7 31.1 0.00061 19.0 31.1 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 KFM28918.1 - 0.0006 19.8 0.2 0.0012 18.8 0.2 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 KFM28918.1 - 0.0013 18.4 0.1 0.0028 17.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KFM28918.1 - 0.0086 16.6 0.0 0.015 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 KFM28918.1 - 0.086 12.4 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.19 KFM28918.1 - 0.15 11.5 0.0 1.1 8.7 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KFM28918.1 - 0.17 12.1 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KFM28918.1 - 0.2 12.2 0.0 0.34 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF3181 PF11378.8 KFM28919.1 - 1.2e-21 76.8 0.0 1.6e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3181) PDDEXK_6 PF04720.12 KFM28920.1 - 4.5e-11 43.1 0.0 7.4e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 PDDEXK-like family of unknown function DUF2012 PF09430.10 KFM28921.1 - 1.8e-09 37.8 0.0 3.6e-09 36.8 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.6 KFM28921.1 - 8.6e-05 22.7 0.0 0.00014 22.1 0.0 1.4 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KFM28921.1 - 0.0014 18.6 0.0 0.0021 18.0 0.0 1.3 1 0 0 1 1 1 1 CarboxypepD_reg-like domain DUF5489 PF17592.2 KFM28921.1 - 0.039 14.5 0.7 0.071 13.7 0.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5489) Glyco_hydro_47 PF01532.20 KFM28922.1 - 5e-97 325.7 0.0 6.3e-97 325.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.22 KFM28922.1 - 1.3e-07 31.5 0.3 1.3e-07 31.5 0.3 2.2 2 0 0 2 2 2 1 PA domain Hydrolase_4 PF12146.8 KFM28923.1 - 6.2e-58 195.9 0.1 7.2e-58 195.7 0.1 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFM28923.1 - 3.1e-12 47.6 7.5 4e-12 47.2 7.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFM28923.1 - 2.9e-09 37.0 0.6 9.5e-09 35.3 0.5 1.9 2 1 0 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 KFM28923.1 - 0.0078 15.8 0.0 1.8 8.1 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 KFM28923.1 - 0.0093 15.8 0.0 0.12 12.2 0.0 2.3 3 0 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.12 KFM28923.1 - 0.045 13.4 0.7 0.11 12.2 0.4 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase LIP PF03583.14 KFM28923.1 - 0.058 12.7 0.6 0.095 12.0 0.6 1.3 1 0 0 1 1 1 0 Secretory lipase Abhydrolase_2 PF02230.16 KFM28923.1 - 0.071 12.9 0.7 0.28 10.9 0.3 2.0 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase DUF2974 PF11187.8 KFM28923.1 - 0.14 11.7 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Thioesterase PF00975.20 KFM28923.1 - 0.39 10.8 2.8 0.88 9.6 2.8 1.6 1 1 0 1 1 1 0 Thioesterase domain DUF2048 PF09752.9 KFM28923.1 - 0.79 8.8 1.8 1.5 7.8 1.8 1.4 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Abhydrolase_3 PF07859.13 KFM28923.1 - 1.1 9.0 4.0 1.9 8.3 3.6 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold PPR_2 PF13041.6 KFM28924.1 - 1.7e-19 69.8 0.0 9.3e-05 22.5 0.0 7.3 6 2 2 8 8 8 4 PPR repeat family PPR_3 PF13812.6 KFM28924.1 - 3.3e-18 65.5 0.0 1.2e-06 28.5 0.0 5.2 5 0 0 5 5 5 3 Pentatricopeptide repeat domain PPR_long PF17177.4 KFM28924.1 - 7.2e-13 48.4 0.0 1.7e-07 30.9 0.0 3.2 3 1 0 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 KFM28924.1 - 2.4e-10 39.9 0.5 0.0059 16.8 0.0 7.6 9 0 0 9 9 9 1 PPR repeat PPR_1 PF12854.7 KFM28924.1 - 1.9e-09 37.1 3.4 0.11 12.2 0.0 6.2 7 0 0 7 7 7 2 PPR repeat ERAP1_C PF11838.8 KFM28924.1 - 7.7 6.0 12.7 0.45 10.0 0.5 3.3 4 1 0 4 4 4 0 ERAP1-like C-terminal domain DUF4722 PF15849.5 KFM28925.1 - 2.9 7.6 6.3 14 5.3 1.5 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4722) GCD14 PF08704.10 KFM28926.1 - 1.8e-89 299.6 0.0 2.3e-89 299.3 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 KFM28926.1 - 4.8e-09 36.2 0.0 6.9e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KFM28926.1 - 3.7e-06 26.8 0.0 6.4e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 KFM28926.1 - 5.8e-06 26.9 0.0 1.1e-05 26.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KFM28926.1 - 4.3e-05 24.5 0.0 9e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFM28926.1 - 0.00099 19.7 0.0 0.0027 18.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 KFM28926.1 - 0.002 17.2 0.0 0.003 16.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase CMAS PF02353.20 KFM28926.1 - 0.0099 15.2 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 KFM28926.1 - 0.017 15.8 0.0 0.039 14.7 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltr_RsmB-F PF01189.17 KFM28926.1 - 0.019 14.6 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F MTS PF05175.14 KFM28926.1 - 0.024 14.2 0.0 0.16 11.5 0.0 2.2 3 0 0 3 3 3 0 Methyltransferase small domain Ubie_methyltran PF01209.18 KFM28926.1 - 0.035 13.4 0.0 0.055 12.8 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PrmA PF06325.13 KFM28926.1 - 0.046 13.1 0.0 0.066 12.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Fibrillarin PF01269.17 KFM28926.1 - 0.12 11.5 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin LGT PF01790.18 KFM28926.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Prolipoprotein diacylglyceryl transferase tRNA-synt_1c PF00749.21 KFM28927.1 - 6.4e-99 330.8 0.1 1.3e-98 329.8 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KFM28927.1 - 8.5e-33 113.7 0.0 1.3e-32 113.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.6 KFM28927.1 - 8.8e-05 22.6 0.0 0.00026 21.1 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFM28927.1 - 0.00026 20.9 0.5 0.00082 19.3 0.5 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KFM28927.1 - 0.0023 17.7 0.0 0.0054 16.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFM28927.1 - 0.052 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DAPG_hydrolase PF18089.1 KFM28928.1 - 0.059 12.9 0.1 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 DAPG hydrolase PhiG domain DDE_Tnp_1 PF01609.21 KFM28928.1 - 0.085 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Transposase DDE domain RhodobacterPufX PF11511.8 KFM28929.1 - 0.18 11.4 0.0 0.18 11.4 0.0 3.6 5 0 0 5 5 5 0 Intrinsic membrane protein PufX Cystatin PF00031.21 KFM28930.1 - 5.8e-06 26.5 0.3 0.068 13.5 0.1 2.4 1 1 1 2 2 2 2 Cystatin domain SQAPI PF16845.5 KFM28930.1 - 0.0076 16.6 0.0 4.9 7.6 0.0 2.3 2 0 0 2 2 2 2 Aspartic acid proteinase inhibitor Pro_3_hydrox_C PF05373.11 KFM28930.1 - 0.17 12.0 0.0 21 5.3 0.0 2.2 1 1 0 2 2 2 0 L-proline 3-hydroxylase, C-terminal Transpos_assoc PF13963.6 KFM28930.1 - 0.25 11.7 1.4 13 6.2 0.1 2.1 1 1 1 2 2 2 0 Transposase-associated domain Cystatin PF00031.21 KFM28931.1 - 0.057 13.7 0.1 0.08 13.2 0.1 1.3 1 0 0 1 1 1 0 Cystatin domain PetN PF03742.14 KFM28935.1 - 7.4e-14 51.3 4.9 1.2e-13 50.7 4.9 1.4 1 0 0 1 1 1 1 PetN DUF3945 PF13101.6 KFM28935.1 - 0.23 11.2 0.0 0.3 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3945) AAR2 PF05282.11 KFM28936.1 - 2.8e-50 171.7 2.8 1e-26 94.2 0.5 3.0 1 1 2 3 3 3 3 AAR2 protein Phosducin PF02114.16 KFM28937.1 - 0.066 12.1 0.0 0.081 11.8 0.0 1.1 1 0 0 1 1 1 0 Phosducin EF-1_beta_acid PF10587.9 KFM28937.1 - 0.12 12.8 1.2 0.12 12.8 1.2 2.1 1 1 1 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region Thioredoxin PF00085.20 KFM28937.1 - 0.14 12.2 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin GDP_Man_Dehyd PF16363.5 KFM28938.1 - 1.1e-61 209.1 0.0 1.7e-61 208.5 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KFM28938.1 - 1.3e-48 165.5 0.2 3.3e-48 164.2 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFM28938.1 - 1.1e-17 63.9 0.0 1.8e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KFM28938.1 - 1.9e-17 63.3 0.0 2.8e-17 62.8 0.0 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KFM28938.1 - 9.8e-10 38.0 0.2 4.6e-08 32.5 0.2 2.4 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 KFM28938.1 - 2e-09 36.9 0.0 7.8e-09 35.0 0.0 1.9 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KFM28938.1 - 2e-05 24.6 0.0 3.3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KFM28938.1 - 0.045 13.3 0.0 0.069 12.7 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Glutaredoxin PF00462.24 KFM28940.1 - 1.1e-26 92.8 0.0 2.4e-16 59.7 0.0 3.3 3 0 0 3 3 3 2 Glutaredoxin Thioredoxin PF00085.20 KFM28940.1 - 2.4e-16 59.6 0.0 4.6e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KFM28940.1 - 0.00012 22.4 0.0 0.00093 19.6 0.0 2.4 2 1 0 2 2 2 1 Thioredoxin-like domain HyaE PF07449.11 KFM28940.1 - 0.0021 18.0 0.0 0.028 14.4 0.0 2.6 2 1 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.6 KFM28940.1 - 0.14 12.4 0.1 2.9 8.1 0.1 2.5 3 0 0 3 3 3 0 Thioredoxin-like DIM1 PF02966.16 KFM28940.1 - 0.19 11.5 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 Mitosis protein DIM1 PikAIV_N PF18605.1 KFM28940.1 - 1.3 8.7 6.3 9.7 5.9 0.5 3.1 3 0 0 3 3 3 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Peptidase_M20 PF01546.28 KFM28941.1 - 4.1e-18 65.8 0.0 7.5e-17 61.7 0.0 2.0 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 KFM28941.1 - 0.038 13.0 0.0 0.24 10.4 0.0 2.0 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase M20_dimer PF07687.14 KFM28941.1 - 0.041 13.8 0.2 0.093 12.7 0.2 1.5 1 0 0 1 1 1 0 Peptidase dimerisation domain MRP-S33 PF08293.11 KFM28942.1 - 5.7e-05 23.3 4.2 0.00049 20.3 4.2 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Ycf66_N PF07444.11 KFM28943.1 - 4.8e-25 87.5 2.5 6e-25 87.2 2.5 1.1 1 0 0 1 1 1 1 Ycf66 protein N-terminus APS_kinase PF01583.20 KFM28944.1 - 2.5e-68 229.0 0.0 3.2e-68 228.6 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 KFM28944.1 - 1.7e-06 28.2 0.0 2.7e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KFM28944.1 - 0.0015 18.0 0.0 0.0017 17.9 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 KFM28944.1 - 0.0031 18.0 0.0 0.0055 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFM28944.1 - 0.0045 17.4 0.0 0.006 17.0 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain CbiA PF01656.23 KFM28944.1 - 0.0052 16.8 0.0 0.0073 16.4 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54 PF00448.22 KFM28944.1 - 0.035 13.7 0.0 0.046 13.3 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PRK PF00485.18 KFM28944.1 - 0.041 13.6 0.0 0.059 13.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family ParA PF10609.9 KFM28944.1 - 0.11 12.0 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase AAA_29 PF13555.6 KFM28944.1 - 0.12 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KFM28944.1 - 0.15 12.5 0.0 0.18 12.3 0.0 1.3 1 0 0 1 1 1 0 ABC transporter G-alpha PF00503.20 KFM28944.1 - 0.18 10.9 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit PgaD PF13994.6 KFM28945.1 - 0.0011 19.0 0.1 0.0012 18.9 0.1 1.1 1 0 0 1 1 1 1 PgaD-like protein HemY_N PF07219.13 KFM28945.1 - 0.0035 17.5 0.3 0.0049 17.0 0.3 1.3 1 0 0 1 1 1 1 HemY protein N-terminus P5-ATPase PF12409.8 KFM28945.1 - 0.071 13.2 0.1 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 P5-type ATPase cation transporter LapA_dom PF06305.11 KFM28945.1 - 1.4 8.8 8.2 1.7 8.5 6.3 2.1 1 1 1 2 2 2 0 Lipopolysaccharide assembly protein A domain Rtf2 PF04641.12 KFM28946.1 - 0.23 10.8 0.0 0.36 10.1 0.0 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger SdpI PF13630.6 KFM28946.1 - 0.4 10.9 2.9 5.2 7.3 0.3 2.8 3 0 0 3 3 3 0 SdpI/YhfL protein family TPT PF03151.16 KFM28947.1 - 1.2e-81 274.3 9.3 1.3e-81 274.1 9.3 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KFM28947.1 - 1e-06 29.0 17.8 0.00031 20.9 3.8 2.5 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KFM28947.1 - 0.028 13.6 4.2 0.04 13.1 4.2 1.6 1 1 0 1 1 1 0 UAA transporter family PP2C PF00481.21 KFM28949.1 - 2.2e-41 142.2 0.0 3.2e-41 141.7 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C Pkinase PF00069.25 KFM28949.1 - 4.1e-36 124.7 0.0 6.5e-36 124.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFM28949.1 - 8.5e-29 100.6 0.0 3.1e-28 98.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFM28949.1 - 2.7e-06 26.4 0.0 3.9e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase PP2C_2 PF13672.6 KFM28949.1 - 0.0075 15.9 0.1 0.021 14.4 0.1 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C APH PF01636.23 KFM28949.1 - 0.013 15.5 1.2 0.038 13.9 0.8 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family NatB_MDM20 PF09797.9 KFM28949.1 - 0.3 10.0 0.0 0.43 9.5 0.0 1.1 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit DEAD PF00270.29 KFM28950.1 - 1e-36 126.3 0.4 6.1e-36 123.8 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM28950.1 - 1.9e-25 89.4 0.7 6.2e-25 87.7 0.2 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFM28950.1 - 6.6e-07 29.5 0.0 1.1e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KFM28950.1 - 0.0031 17.8 0.2 0.027 14.7 0.1 2.4 1 1 1 2 2 2 1 AAA domain SecA_DEAD PF07517.14 KFM28950.1 - 0.037 13.3 0.0 0.058 12.7 0.0 1.3 1 0 0 1 1 1 0 SecA DEAD-like domain AAA_30 PF13604.6 KFM28950.1 - 0.067 12.9 0.1 0.17 11.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain RrnaAD PF00398.20 KFM28951.1 - 3.5e-33 114.8 0.0 6.9e-16 58.1 0.0 2.0 1 1 1 2 2 2 2 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.6 KFM28951.1 - 0.0032 17.3 0.0 0.1 12.4 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain peroxidase PF00141.23 KFM28954.1 - 2.1e-25 89.8 0.0 2.7e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 Peroxidase Ribosomal_S21 PF01165.20 KFM28957.1 - 1.2e-17 63.4 9.4 1.8e-17 62.8 9.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 DUF2828 PF11443.8 KFM28957.1 - 0.023 12.8 0.0 0.024 12.8 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DnaJ_CXXCXGXG PF00684.19 KFM28958.1 - 0.023 15.0 13.3 0.024 15.0 11.6 2.0 2 1 1 3 3 3 0 DnaJ central domain GST_C_5 PF16865.5 KFM28959.1 - 0.011 16.3 0.0 0.019 15.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Qn_am_d_aII PF14930.6 KFM28959.1 - 0.019 15.3 0.4 1.8 8.9 0.1 2.2 2 0 0 2 2 2 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain II DUF819 PF05684.12 KFM28961.1 - 1.1e-65 222.1 23.8 1.3e-65 221.9 23.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF819) Pentapeptide_2 PF01469.18 KFM28962.1 - 7.7e-05 22.5 30.9 0.00023 21.0 29.5 2.4 2 1 0 2 2 2 1 Pentapeptide repeats (8 copies) Pentapeptide_2 PF01469.18 KFM28963.1 - 2e-05 24.4 29.6 5.1e-05 23.1 29.7 1.6 1 1 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_2 PF01469.18 KFM28964.1 - 0.0003 20.6 26.3 0.00048 20.0 26.3 1.3 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) PRIMA1 PF16101.5 KFM28964.1 - 5.8 7.0 8.2 12 5.9 8.2 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 PucR PF07905.11 KFM28965.1 - 0.059 13.6 0.1 0.11 12.7 0.1 1.4 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family ApbA_C PF08546.11 KFM28965.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal DNA_binding_1 PF01035.20 KFM28966.1 - 1.8e-26 92.0 0.0 2.8e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Diphthami_syn_2 PF01902.17 KFM28967.1 - 3.3e-31 108.5 0.0 7.7e-31 107.3 0.0 1.5 1 1 0 1 1 1 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 KFM28967.1 - 5.4e-10 39.3 0.0 0.0013 18.7 0.0 2.7 1 1 1 2 2 2 2 Endoribonuclease L-PSP OMPdecase PF00215.24 KFM28968.1 - 8.5e-75 251.2 0.0 1.2e-74 250.7 0.0 1.2 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pribosyltran PF00156.27 KFM28968.1 - 2.1e-10 40.4 0.0 4.1e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Alpha-amyl_C2 PF07821.12 KFM28969.1 - 3.5e-19 68.8 0.8 6e-19 68.0 0.2 1.8 2 0 0 2 2 2 1 Alpha-amylase C-terminal beta-sheet domain Alpha-amylase PF00128.24 KFM28969.1 - 4.4e-12 46.2 0.0 1.7e-08 34.4 0.0 2.8 3 0 0 3 3 3 2 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 KFM28969.1 - 0.33 9.1 0.0 1 7.4 0.0 1.6 2 0 0 2 2 2 0 Glycosyl hydrolase family 70 AAA_18 PF13238.6 KFM28970.1 - 3.2e-08 34.2 0.0 3.1e-07 31.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain PRK PF00485.18 KFM28970.1 - 1e-06 28.6 0.0 1.3e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 KFM28970.1 - 2.2e-05 24.6 0.5 0.038 14.1 0.1 2.2 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.6 KFM28970.1 - 0.0011 19.4 0.0 0.061 13.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 KFM28970.1 - 0.0011 18.6 0.0 0.45 10.2 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase MeaB PF03308.16 KFM28970.1 - 0.0027 16.7 0.1 0.0041 16.1 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 KFM28970.1 - 0.0054 17.3 0.0 0.0096 16.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 KFM28970.1 - 0.02 15.3 0.0 0.037 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 KFM28970.1 - 0.02 14.2 1.7 0.038 13.3 0.2 1.9 2 0 0 2 2 2 0 Zeta toxin dNK PF01712.19 KFM28970.1 - 0.022 14.6 0.0 6.3 6.6 0.0 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase CoaE PF01121.20 KFM28970.1 - 0.023 14.4 0.3 0.71 9.5 0.1 2.1 2 0 0 2 2 2 0 Dephospho-CoA kinase KTI12 PF08433.10 KFM28970.1 - 0.026 14.0 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_30 PF13604.6 KFM28970.1 - 0.027 14.2 0.6 0.045 13.5 0.6 1.4 1 0 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 KFM28970.1 - 0.056 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Viral_helicase1 PF01443.18 KFM28970.1 - 0.057 13.2 0.0 0.082 12.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 KFM28970.1 - 0.059 13.3 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 KFM28970.1 - 0.067 13.4 0.0 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KFM28970.1 - 0.075 12.3 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.22 KFM28970.1 - 0.084 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_5 PF07728.14 KFM28970.1 - 0.1 12.6 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 KFM28970.1 - 0.14 12.0 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 NTPase AAA_24 PF13479.6 KFM28970.1 - 0.18 11.5 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KFM28970.1 - 0.21 11.7 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 KFM28970.1 - 0.22 11.8 0.0 0.36 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain EF-hand_1 PF00036.32 KFM28971.1 - 1.3e-09 36.9 1.7 0.00022 20.5 0.1 2.3 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KFM28971.1 - 1.9e-08 33.6 0.2 0.00065 19.4 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KFM28971.1 - 2.3e-06 28.0 0.0 3.9e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KFM28971.1 - 2.6e-06 26.7 1.2 0.0097 15.4 0.1 2.2 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KFM28971.1 - 0.00027 20.7 0.2 0.00055 19.7 0.1 1.6 1 1 1 2 2 2 1 EF-hand domain pair ACOX PF01756.19 KFM28973.1 - 3.1e-31 108.3 0.0 5.3e-31 107.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 KFM28973.1 - 3.9e-17 62.2 0.0 7.1e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KFM28973.1 - 6.9e-09 36.1 0.1 2e-08 34.6 0.1 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Toxin_5 PF05294.13 KFM28973.1 - 0.051 14.0 0.5 0.11 12.9 0.5 1.5 1 0 0 1 1 1 0 Scorpion short toxin Acyl-CoA_dh_N PF02771.16 KFM28973.1 - 0.15 12.7 0.0 0.5 11.0 0.0 2.0 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain Tyr-DNA_phospho PF06087.12 KFM28974.1 - 1.2e-38 133.1 0.0 1.6e-38 132.8 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase XPB_DRD PF18458.1 KFM28974.1 - 0.19 11.6 0.2 0.51 10.3 0.1 1.8 2 0 0 2 2 2 0 Xeroderma pigmentosum group B helicase damage recognition domain CobN-Mg_chel PF02514.16 KFM28975.1 - 8.6e-223 742.4 0.0 8.9e-171 570.1 0.0 3.6 2 1 1 3 3 3 3 CobN/Magnesium Chelatase DUF3479 PF11965.8 KFM28975.1 - 2.6e-40 138.2 0.0 4.3e-40 137.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3479) TilS PF09179.11 KFM28975.1 - 0.14 12.7 0.9 0.5 10.9 0.3 2.3 2 0 0 2 2 2 0 TilS substrate binding domain Menin PF05053.13 KFM28976.1 - 5.6e-12 44.9 0.5 7.8e-07 27.9 0.9 2.1 2 0 0 2 2 2 2 Menin UCH PF00443.29 KFM28978.1 - 4.6e-29 101.7 0.0 5.9e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KFM28978.1 - 6.4e-13 48.8 1.1 1.1e-12 48.1 1.1 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 KFM28978.1 - 0.0011 18.6 0.0 0.11 12.1 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Golgin_A5 PF09787.9 KFM28979.1 - 0.002 17.6 10.0 0.002 17.6 10.0 9.5 3 3 5 10 10 10 6 Golgin subfamily A member 5 adh_short PF00106.25 KFM28980.1 - 6.3e-31 107.4 0.0 1.3e-24 86.8 0.2 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFM28980.1 - 4.3e-18 65.7 0.0 6e-17 62.0 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM28980.1 - 8.7e-09 35.5 0.7 2.3e-08 34.2 0.7 1.6 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFM28980.1 - 4.7e-06 26.2 0.0 6.4e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFM28980.1 - 0.0044 16.5 0.0 0.0061 16.0 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase WD40 PF00400.32 KFM28981.1 - 4e-18 65.4 0.8 0.00035 21.3 0.0 6.1 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM28981.1 - 3.7e-14 52.8 0.1 0.0082 16.4 0.0 5.2 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KFM28981.1 - 3.9e-05 23.5 0.0 0.35 10.9 0.0 3.8 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KFM28981.1 - 0.00035 20.5 0.0 0.0063 16.4 0.0 2.6 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 KFM28981.1 - 0.00068 17.8 0.0 0.0069 14.5 0.0 2.2 1 1 2 3 3 3 1 IKI3 family WHAMM-JMY_N PF15920.5 KFM28981.1 - 0.14 12.1 0.1 0.54 10.2 0.0 2.0 2 0 0 2 2 2 0 N-terminal of Junction-mediating and WASP homolog-associated AA_permease_2 PF13520.6 KFM28982.1 - 2e-36 125.8 35.1 3.3e-36 125.1 35.1 1.3 1 0 0 1 1 1 1 Amino acid permease HORMA PF02301.18 KFM28982.1 - 2.1e-30 105.9 0.0 8e-29 100.8 0.0 2.1 1 1 0 1 1 1 1 HORMA domain AA_permease PF00324.21 KFM28982.1 - 2.2e-24 85.9 38.1 2.2e-24 85.9 38.1 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 KFM28982.1 - 1.5e-12 47.4 1.4 1.5e-12 47.4 1.4 2.7 3 0 0 3 3 3 1 C-terminus of AA_permease Spore_permease PF03845.13 KFM28982.1 - 0.18 10.6 6.9 0.077 11.8 0.2 2.2 2 0 0 2 2 2 0 Spore germination protein MBOAT PF03062.19 KFM28983.1 - 3.1e-23 82.7 18.2 5e-23 82.0 18.2 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family PH PF00169.29 KFM28983.1 - 6.3e-10 39.5 0.0 1.3e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KFM28983.1 - 0.0019 18.4 0.0 0.0042 17.3 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain AKNA PF12443.8 KFM28983.1 - 0.023 15.4 0.1 0.048 14.3 0.1 1.4 1 0 0 1 1 1 0 AT-hook-containing transcription factor PH_11 PF15413.6 KFM28983.1 - 0.033 14.6 0.1 0.13 12.7 0.1 2.0 1 1 0 1 1 1 0 Pleckstrin homology domain MBOAT_2 PF13813.6 KFM28983.1 - 0.35 11.2 7.7 1.1 9.6 7.7 1.8 1 0 0 1 1 1 0 Membrane bound O-acyl transferase family UPF0052 PF01933.18 KFM28984.1 - 1.5e-44 152.4 0.0 1.9e-44 152.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 FA_desaturase PF00487.24 KFM28985.1 - 8.5e-35 120.8 11.9 1.2e-34 120.3 11.9 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF4748 PF15932.5 KFM28986.1 - 0.0018 18.0 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4748) DUF2746 PF10874.8 KFM28986.1 - 0.094 13.1 0.0 0.21 12.0 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2746) RsgA_GTPase PF03193.16 KFM28987.1 - 4.4e-47 160.1 0.0 6.6e-47 159.5 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase RsgA_N PF16745.5 KFM28987.1 - 0.00032 20.4 0.0 0.00092 18.9 0.0 1.7 2 0 0 2 2 2 1 RsgA N-terminal domain MMR_HSR1 PF01926.23 KFM28987.1 - 0.00045 20.3 0.0 0.00091 19.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KFM28987.1 - 0.0011 19.5 0.0 0.0024 18.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 KFM28987.1 - 0.0077 16.6 1.5 0.024 15.0 0.1 2.3 3 0 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 KFM28987.1 - 0.0092 15.7 0.2 0.019 14.7 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain cobW PF02492.19 KFM28987.1 - 0.045 13.3 0.2 4.3 6.9 0.0 2.5 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 KFM28987.1 - 0.078 13.2 0.1 0.078 13.2 0.1 2.2 2 1 1 3 3 3 0 AAA domain Dynamin_N PF00350.23 KFM28987.1 - 0.093 12.8 0.4 0.95 9.5 0.1 2.2 1 1 1 2 2 2 0 Dynamin family IstB_IS21 PF01695.17 KFM28987.1 - 0.12 12.1 0.1 0.22 11.2 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Septin PF00735.18 KFM28987.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Septin DUF815 PF05673.13 KFM28987.1 - 0.16 11.1 0.2 0.29 10.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MMR_HSR1_Xtn PF16897.5 KFM28987.1 - 0.26 11.3 0.0 0.43 10.6 0.0 1.2 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain YhzD PF14120.6 KFM28987.1 - 0.41 10.8 5.2 87 3.3 5.2 2.4 1 1 0 1 1 1 0 YhzD-like protein VWA PF00092.28 KFM28988.1 - 5.2e-16 59.4 0.0 1.1e-12 48.6 0.0 2.2 1 1 1 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 KFM28988.1 - 3.3e-09 37.3 0.1 2.3e-07 31.4 0.1 2.3 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KFM28988.1 - 0.0042 17.0 0.1 0.031 14.2 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 KFM28988.1 - 0.0075 16.4 0.1 0.28 11.3 0.1 2.4 1 1 0 1 1 1 1 vWA found in TerF C terminus VWA_CoxE PF05762.14 KFM28988.1 - 0.013 14.9 0.0 0.031 13.7 0.0 1.6 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein DNA_pol_B PF00136.21 KFM28990.1 - 9.6e-73 245.4 0.0 1.4e-72 244.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KFM28990.1 - 2.6e-05 23.5 0.0 0.41 9.7 0.0 3.2 2 2 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KFM28990.1 - 0.00042 20.7 7.2 0.00049 20.5 0.2 2.4 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta DUF3239 PF11580.8 KFM28990.1 - 0.15 12.4 0.1 0.4 11.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3239) CRAL_TRIO PF00650.20 KFM28991.1 - 2.6e-14 53.2 0.0 3.9e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain DUF1077 PF06417.12 KFM28992.1 - 6.9e-25 87.4 0.1 9e-25 87.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) CBS PF00571.28 KFM28993.1 - 5.1e-21 74.9 1.7 3e-15 56.4 0.2 2.2 2 0 0 2 2 2 2 CBS domain DASH_Spc19 PF08287.11 KFM28993.1 - 0.034 14.0 0.0 0.093 12.6 0.0 1.6 2 0 0 2 2 2 0 Spc19 Peptidase_C97 PF05903.14 KFM28994.1 - 6.2e-35 120.3 0.0 8e-35 119.9 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LEA_4 PF02987.16 KFM28996.1 - 2e-06 27.8 17.6 1.4e-05 25.1 3.3 3.2 2 1 0 2 2 2 1 Late embryogenesis abundant protein YtxH PF12732.7 KFM28996.1 - 0.0001 22.7 10.3 0.025 15.1 2.7 2.1 1 1 1 2 2 2 2 YtxH-like protein ApoLp-III PF07464.11 KFM28996.1 - 0.00087 19.4 4.6 0.0012 18.9 4.6 1.2 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) DUF883 PF05957.13 KFM28996.1 - 0.0015 19.1 11.0 0.23 12.1 3.6 2.0 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.18 KFM28996.1 - 0.0028 17.5 4.7 0.0037 17.2 4.7 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DivIVA PF05103.13 KFM28996.1 - 0.51 10.4 9.3 0.057 13.5 4.3 1.7 1 1 1 2 2 2 0 DivIVA protein Grg1 PF11034.8 KFM28996.1 - 0.92 9.8 14.8 0.61 10.4 1.6 3.2 1 1 2 3 3 3 0 Glucose-repressible protein Grg1 MT0933_antitox PF14013.6 KFM28996.1 - 2.7 8.4 13.6 11 6.5 1.5 3.1 1 1 2 3 3 3 0 MT0933-like antitoxin protein Mit_KHE1 PF10173.9 KFM28996.1 - 2.8 8.0 4.8 10 6.1 0.2 2.0 1 1 1 2 2 2 0 Mitochondrial K+-H+ exchange-related ATP-synt_B PF00430.18 KFM28996.1 - 6.2 6.9 20.0 6.8 6.8 10.7 2.0 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) EFTUD2 PF16004.5 KFM28996.1 - 8.5 7.0 8.6 2.4 8.7 0.2 2.1 1 1 1 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus DOT1 PF08123.13 KFM28997.1 - 3.6e-06 26.7 0.0 5.4e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Ribosomal_L1 PF00687.21 KFM28998.1 - 1.3e-45 155.7 0.0 1.8e-45 155.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family FHA PF00498.26 KFM28999.1 - 0.03 14.7 0.0 0.049 14.0 0.0 1.4 1 0 0 1 1 1 0 FHA domain DnaJ PF00226.31 KFM29002.1 - 3.1e-12 46.4 0.0 5e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain CN_hydrolase PF00795.22 KFM29005.1 - 5.2e-54 183.3 0.1 6.1e-54 183.1 0.1 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase FliT PF05400.13 KFM29008.1 - 0.025 15.4 0.6 0.13 13.1 0.1 2.2 3 0 0 3 3 3 0 Flagellar protein FliT HrpB7 PF09486.10 KFM29008.1 - 0.034 14.5 2.0 0.047 14.1 2.0 1.2 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) HGTP_anticodon PF03129.20 KFM29009.1 - 1.9e-20 72.8 0.0 5.3e-20 71.4 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KFM29009.1 - 9.8e-12 45.2 0.0 7.7e-11 42.3 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS PF00458.20 KFM29009.1 - 9.3e-09 35.3 7.9 4.6e-08 33.1 8.1 2.0 2 0 0 2 2 2 1 WHEP-TRS domain GntR PF00392.21 KFM29009.1 - 0.2 11.3 1.3 0.75 9.5 0.1 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family Rep_fac-A_3 PF08661.11 KFM29010.1 - 7e-18 64.9 0.0 7.7e-18 64.8 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Nrap PF03813.14 KFM29011.1 - 1.2e-30 106.6 0.0 1.6e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D5 PF17406.2 KFM29011.1 - 4.4e-23 81.8 0.4 1.8e-21 76.6 0.4 2.4 1 1 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D4 PF17405.2 KFM29011.1 - 7.2e-18 64.7 0.0 1.3e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D3 PF17404.2 KFM29011.1 - 5.4e-13 49.3 0.0 1e-12 48.4 0.0 1.4 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D2 PF17403.2 KFM29011.1 - 0.24 11.2 0.4 13 5.5 0.1 2.9 3 0 0 3 3 3 0 Nrap protein PAP/OAS-like domain eIF-4B PF06273.11 KFM29012.1 - 1.5e-13 50.7 44.9 1.8e-11 43.9 26.1 5.3 1 1 2 3 3 3 2 Plant specific eukaryotic initiation factor 4B Mito_carr PF00153.27 KFM29013.1 - 2.2e-43 146.1 11.2 1.7e-18 66.3 0.3 4.1 3 1 1 4 4 4 4 Mitochondrial carrier protein AAA PF00004.29 KFM29015.1 - 8.1e-17 61.9 0.0 1.2e-16 61.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KFM29015.1 - 8.1e-15 55.0 0.0 1.2e-12 47.9 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 KFM29015.1 - 7.4e-12 45.5 0.0 1.5e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_22 PF13401.6 KFM29015.1 - 5.4e-06 26.7 0.0 0.0035 17.6 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KFM29015.1 - 5.9e-06 26.8 0.4 0.00046 20.6 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain Rad17 PF03215.15 KFM29015.1 - 1.8e-05 24.8 0.0 3.7e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 KFM29015.1 - 3e-05 23.8 0.0 0.00011 21.9 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KFM29015.1 - 7.9e-05 22.5 0.0 0.00013 21.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KFM29015.1 - 0.00023 20.6 0.0 0.0047 16.3 0.0 2.3 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 KFM29015.1 - 0.00026 21.3 0.1 0.24 11.7 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_30 PF13604.6 KFM29015.1 - 0.00039 20.2 0.0 0.00092 19.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 KFM29015.1 - 0.00054 20.2 0.0 0.0013 19.0 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA_11 PF13086.6 KFM29015.1 - 0.0011 18.8 0.0 0.0028 17.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KFM29015.1 - 0.0028 17.7 0.0 0.011 15.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF2075 PF09848.9 KFM29015.1 - 0.0034 16.7 0.0 0.026 13.7 0.0 1.9 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 KFM29015.1 - 0.0036 17.3 0.0 0.0056 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KFM29015.1 - 0.0058 16.7 0.0 0.017 15.1 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_25 PF13481.6 KFM29015.1 - 0.023 14.3 0.1 0.079 12.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KFM29015.1 - 0.023 14.9 0.0 0.04 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 KFM29015.1 - 0.029 14.5 0.0 3.2 7.9 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain DNA_pol3_delta PF06144.13 KFM29015.1 - 0.03 14.1 0.0 0.051 13.4 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit NACHT PF05729.12 KFM29015.1 - 0.032 14.1 0.0 6.5 6.6 0.0 3.0 2 1 0 2 2 2 0 NACHT domain ADK PF00406.22 KFM29015.1 - 0.046 13.8 0.1 7.5 6.6 0.0 2.9 2 1 1 3 3 3 0 Adenylate kinase DEAD PF00270.29 KFM29015.1 - 0.048 13.4 0.1 7.2 6.3 0.0 2.2 1 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_18 PF13238.6 KFM29015.1 - 0.054 14.0 0.0 0.14 12.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.11 KFM29015.1 - 0.07 13.0 0.0 0.18 11.7 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KFM29015.1 - 0.073 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KFM29015.1 - 0.097 13.1 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 KFM29015.1 - 0.1 12.3 0.0 0.45 10.2 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.16 KFM29015.1 - 0.11 11.9 0.3 2.8 7.3 0.0 2.2 1 1 0 2 2 2 0 PhoH-like protein AAA_7 PF12775.7 KFM29015.1 - 0.13 11.7 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region TIP49 PF06068.13 KFM29015.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Sigma54_activat PF00158.26 KFM29015.1 - 0.16 11.6 0.0 3.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF4350 PF14258.6 KFM29017.1 - 0.058 13.8 0.0 15 6.1 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) WD40 PF00400.32 KFM29018.1 - 3.9e-08 33.8 0.8 0.0083 17.0 0.0 4.8 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM29018.1 - 6.5e-06 26.4 0.0 0.11 12.8 0.0 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KFM29018.1 - 0.018 14.6 1.8 2.4 7.7 0.2 2.5 2 1 0 2 2 2 0 PQQ-like domain RRM_1 PF00076.22 KFM29019.1 - 5.1e-06 26.2 0.0 2.5e-05 24.0 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFM29019.1 - 0.0016 18.4 0.0 0.003 17.5 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Torus PF16131.5 KFM29019.1 - 0.018 15.8 0.6 0.032 14.9 0.6 1.3 1 0 0 1 1 1 0 Torus domain PetM PF08041.11 KFM29020.1 - 0.00029 20.3 6.4 0.00045 19.7 6.4 1.3 1 0 0 1 1 1 1 PetM family of cytochrome b6f complex subunit 7 CMD PF02627.20 KFM29021.1 - 0.0007 19.6 0.1 0.0026 17.8 0.0 2.0 3 0 0 3 3 3 1 Carboxymuconolactone decarboxylase family SCP2 PF02036.17 KFM29022.1 - 4.3e-22 78.5 0.1 5.3e-22 78.2 0.1 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 KFM29022.1 - 2.8e-06 27.6 0.0 3e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal zf-CXXC PF02008.20 KFM29023.1 - 0.027 14.5 0.9 0.052 13.6 0.9 1.5 1 0 0 1 1 1 0 CXXC zinc finger domain Suc_Fer-like PF06999.12 KFM29024.1 - 4.3e-19 69.2 0.3 5.6e-18 65.5 0.3 2.0 1 1 0 1 1 1 1 Sucrase/ferredoxin-like ATP1G1_PLM_MAT8 PF02038.16 KFM29025.1 - 0.11 11.9 1.5 2 7.9 0.3 2.3 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family DUF1917 PF08939.10 KFM29026.1 - 1.8e-25 90.3 0.0 8.8e-25 88.1 0.0 1.8 1 1 0 2 2 2 1 Domain of unknown function (DUF1917) DUF747 PF05346.11 KFM29027.1 - 9.8e-47 160.0 0.0 2.5e-41 142.2 0.0 2.2 1 1 1 2 2 2 2 Eukaryotic membrane protein family NUDIX PF00293.28 KFM29028.1 - 7.6e-18 64.8 0.1 9.1e-18 64.6 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KFM29028.1 - 0.0017 18.3 0.1 0.0026 17.7 0.1 1.3 1 1 0 1 1 1 1 NUDIX domain MIP PF00230.20 KFM29029.1 - 2e-51 174.9 15.8 2.7e-51 174.5 15.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein PRP38 PF03371.15 KFM29030.1 - 2.6e-53 180.5 0.0 3.1e-53 180.2 0.0 1.1 1 0 0 1 1 1 1 PRP38 family SART-1 PF03343.13 KFM29030.1 - 0.025 13.2 0.9 0.029 12.9 0.0 1.5 2 0 0 2 2 2 0 SART-1 family PRP38_assoc PF12871.7 KFM29030.1 - 0.076 13.6 0.4 0.11 13.1 0.4 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term ComS PF17584.2 KFM29031.1 - 0.069 12.7 0.6 0.1 12.1 0.6 1.4 1 0 0 1 1 1 0 Bacillus competence protein S Fructosamin_kin PF03881.14 KFM29032.1 - 5.2e-54 183.4 0.0 7.1e-54 183.0 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase EcKinase PF02958.20 KFM29032.1 - 0.046 13.0 0.0 0.072 12.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase bZIP_1 PF00170.21 KFM29032.1 - 0.068 13.3 4.7 0.13 12.4 4.7 1.3 1 0 0 1 1 1 0 bZIP transcription factor MULE PF10551.9 KFM29033.1 - 0.00033 21.0 0.1 0.0012 19.2 0.0 2.0 2 0 0 2 2 2 1 MULE transposase domain zf-Tim10_DDP PF02953.15 KFM29034.1 - 0.046 13.4 0.0 0.065 12.9 0.0 1.3 1 0 0 1 1 1 0 Tim10/DDP family zinc finger DUF3404 PF11884.8 KFM29034.1 - 0.1 11.8 0.1 0.1 11.8 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3404) Alpha-amylase PF00128.24 KFM29035.1 - 5.3e-24 85.4 0.0 9.3e-19 68.2 0.0 3.1 2 1 1 3 3 3 3 Alpha amylase, catalytic domain CBM_48 PF02922.18 KFM29035.1 - 1.5e-08 34.9 0.0 1e-07 32.2 0.0 2.3 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) DUF3459 PF11941.8 KFM29035.1 - 0.0038 17.5 1.7 0.063 13.6 1.7 2.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3459) hDGE_amylase PF14701.6 KFM29035.1 - 0.031 13.4 0.0 0.045 12.9 0.0 1.1 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain VIT1 PF01988.19 KFM29036.1 - 1.8e-35 122.8 8.1 2e-35 122.6 8.1 1.0 1 0 0 1 1 1 1 VIT family tRNA_synt_2f PF02092.17 KFM29037.1 - 3.9e-164 547.5 0.0 5.8e-164 546.9 0.0 1.3 1 0 0 1 1 1 1 Glycyl-tRNA synthetase beta subunit tRNA-synt_2e PF02091.15 KFM29037.1 - 4e-123 410.1 0.0 5.7e-123 409.6 0.0 1.2 1 0 0 1 1 1 1 Glycyl-tRNA synthetase alpha subunit PAC2 PF09754.9 KFM29037.1 - 0.0048 16.9 0.3 0.044 13.8 0.1 2.7 1 1 1 2 2 2 1 PAC2 family DALR_1 PF05746.15 KFM29037.1 - 0.0076 16.4 0.0 0.019 15.1 0.0 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain Arf PF00025.21 KFM29040.1 - 2.2e-74 248.7 0.0 2.5e-74 248.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFM29040.1 - 3.6e-14 53.0 0.0 4.7e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFM29040.1 - 2.9e-12 46.5 0.0 3.4e-12 46.2 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KFM29040.1 - 1.2e-11 44.3 0.0 1.5e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KFM29040.1 - 1.7e-10 40.6 0.0 1.6e-07 30.9 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KFM29040.1 - 1.1e-08 34.8 0.0 1.3e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFM29040.1 - 1.8e-05 24.8 0.0 4.3e-05 23.6 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFM29040.1 - 0.061 12.8 0.2 0.2 11.1 0.3 1.9 2 1 0 2 2 2 0 Ferrous iron transport protein B CI-B14_5a PF07347.12 KFM29041.1 - 0.00075 19.3 0.0 0.00088 19.1 0.0 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) WHIM1 PF15612.6 KFM29041.1 - 0.01 15.4 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 zf-C3HC4_3 PF13920.6 KFM29042.1 - 9e-07 28.7 10.2 9e-07 28.7 10.2 3.8 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFM29042.1 - 0.0043 16.9 5.8 0.0043 16.9 5.8 3.5 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Phe_tRNA-synt_N PF02912.18 KFM29044.1 - 0.034 14.1 0.2 0.076 13.0 0.2 1.5 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain ATP-synt_B PF00430.18 KFM29044.1 - 0.78 9.8 5.0 3.2 7.9 5.0 2.0 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) PROL5-SMR PF15621.6 KFM29044.1 - 1.6 9.3 7.0 3 8.4 7.0 1.3 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family CYTH PF01928.21 KFM29045.1 - 3.8e-23 82.3 0.1 4.5e-23 82.1 0.1 1.0 1 0 0 1 1 1 1 CYTH domain LETM1 PF07766.13 KFM29046.1 - 2.3e-13 50.1 0.0 4.7e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 LETM1-like protein Pox_A_type_inc PF04508.12 KFM29046.1 - 0.12 12.3 0.9 0.54 10.2 0.1 2.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat UQ_con PF00179.26 KFM29047.1 - 2e-47 160.4 0.0 3.3e-47 159.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Myb_DNA-binding PF00249.31 KFM29047.1 - 2.3e-07 30.9 1.6 0.00021 21.4 0.4 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFM29047.1 - 1.1e-05 25.6 0.6 0.0013 19.0 0.1 2.8 3 0 0 3 3 3 1 Myb-like DNA-binding domain Rap1_C PF11626.8 KFM29047.1 - 0.0099 15.9 1.6 0.4 10.8 1.6 2.9 1 1 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain RWD PF05773.22 KFM29047.1 - 0.08 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 RWD domain Na_H_Exchanger PF00999.21 KFM29048.1 - 3.6e-41 141.2 43.0 8.2e-22 77.5 10.1 2.1 1 1 1 2 2 2 2 Sodium/hydrogen exchanger family TcdA_TcdB_pore PF12920.7 KFM29048.1 - 9.3 4.4 5.4 17 3.5 5.4 1.4 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain IspD PF01128.19 KFM29052.1 - 1.1e-51 175.7 0.1 1.4e-51 175.4 0.1 1.1 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NTP_transf_3 PF12804.7 KFM29052.1 - 7.7e-10 39.3 0.6 7.7e-10 39.3 0.6 1.6 2 0 0 2 2 2 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 KFM29052.1 - 0.016 14.8 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase CTP_transf_3 PF02348.19 KFM29052.1 - 0.21 11.5 0.0 0.31 10.9 0.0 1.2 1 0 0 1 1 1 0 Cytidylyltransferase TRAP_beta PF05753.14 KFM29053.1 - 1.2e-22 80.1 1.4 2.9e-22 78.9 0.3 1.8 1 1 1 2 2 2 1 Translocon-associated protein beta (TRAPB) DUF11 PF01345.18 KFM29053.1 - 0.00034 20.9 0.4 0.00081 19.7 0.4 1.8 1 1 0 1 1 1 1 Domain of unknown function DUF11 NPCBM_assoc PF10633.9 KFM29053.1 - 0.00052 20.2 0.5 0.0013 19.0 0.5 1.6 1 0 0 1 1 1 1 NPCBM-associated, NEW3 domain of alpha-galactosidase bMG10 PF17973.1 KFM29053.1 - 0.046 13.9 0.2 0.11 12.7 0.1 1.6 1 1 0 1 1 1 0 Bacterial Alpha-2-macroglobulin MG10 domain CARDB PF07705.11 KFM29053.1 - 0.053 13.8 0.3 0.19 12.0 0.3 1.9 1 1 0 1 1 1 0 CARDB Pro_isomerase PF00160.21 KFM29054.1 - 1.5e-46 158.6 0.0 1.7e-46 158.4 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Lycopene_cycl PF05834.12 KFM29055.1 - 4e-98 328.9 2.7 5.9e-56 190.1 0.0 2.0 1 1 1 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KFM29055.1 - 6e-10 38.8 0.8 2.5e-05 23.7 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFM29055.1 - 4.8e-06 26.0 0.2 1.1e-05 24.8 0.2 1.6 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KFM29055.1 - 1.2e-05 24.8 0.0 1.7e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KFM29055.1 - 1.2e-05 24.6 3.2 0.00034 19.8 3.2 2.2 1 1 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 KFM29055.1 - 8.7e-05 21.4 1.4 0.0061 15.3 0.4 2.1 2 0 0 2 2 2 2 HI0933-like protein Trp_halogenase PF04820.14 KFM29055.1 - 0.00028 19.9 2.1 0.0064 15.4 0.1 2.2 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_9 PF13454.6 KFM29055.1 - 0.00055 20.0 2.8 0.15 12.0 0.4 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KFM29055.1 - 0.00089 18.4 5.3 0.0018 17.5 5.1 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KFM29055.1 - 0.0011 18.7 14.6 0.0072 16.0 0.5 2.6 2 1 1 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 KFM29055.1 - 0.0067 15.7 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KFM29055.1 - 0.0082 16.4 0.7 0.0082 16.4 0.7 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KFM29055.1 - 0.0085 16.6 0.2 0.13 12.9 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase PI3_PI4_kinase PF00454.27 KFM29056.1 - 2.2e-27 96.5 0.0 7.9e-25 88.1 0.0 2.2 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KFM29056.1 - 8.2e-05 22.1 0.1 0.00014 21.3 0.1 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 KFM29056.1 - 0.13 11.6 0.0 0.19 11.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Cpn60_TCP1 PF00118.24 KFM29057.1 - 5.2e-144 480.5 7.7 6.1e-144 480.3 7.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family IF-2B PF01008.17 KFM29058.1 - 3.1e-69 233.3 0.0 3.6e-69 233.1 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family ECH_2 PF16113.5 KFM29059.1 - 3e-108 362.3 0.6 4.7e-104 348.5 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 KFM29059.1 - 2.1e-19 69.8 0.9 4.9e-16 58.8 0.1 2.7 1 1 2 3 3 3 2 Enoyl-CoA hydratase/isomerase Rtf2 PF04641.12 KFM29060.1 - 4.1e-48 164.0 0.0 5.6e-48 163.6 0.0 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger ACC_epsilon PF13822.6 KFM29060.1 - 1.2 9.8 12.7 0.31 11.7 8.5 2.3 2 1 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit ATP_bind_1 PF03029.17 KFM29061.1 - 2.4e-71 240.3 0.0 3.7e-71 239.7 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Alpha-amylase_C PF02806.18 KFM29061.1 - 1.9e-14 53.9 0.4 1e-13 51.6 0.1 2.4 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 KFM29061.1 - 2.8e-11 43.6 1.8 1e-09 38.4 0.1 2.4 1 1 0 2 2 2 1 Alpha amylase, catalytic domain CBM_48 PF02922.18 KFM29061.1 - 6.3e-11 42.5 0.6 1.6e-10 41.2 0.6 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) GTP_EFTU PF00009.27 KFM29061.1 - 0.00074 19.1 0.1 0.0027 17.3 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain hDGE_amylase PF14701.6 KFM29061.1 - 0.0077 15.4 0.4 0.24 10.4 0.0 2.3 2 0 0 2 2 2 1 Glycogen debranching enzyme, glucanotransferase domain MeaB PF03308.16 KFM29061.1 - 0.029 13.4 0.3 5.6 5.9 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 KFM29061.1 - 0.034 14.2 0.0 0.1 12.7 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase Acetyltransf_1 PF00583.25 KFM29062.1 - 7.9e-12 45.4 0.0 9.8e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFM29062.1 - 2.4e-06 27.9 0.0 3.1e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFM29062.1 - 3.1e-06 27.2 0.0 3.7e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFM29062.1 - 0.16 12.0 0.1 0.27 11.2 0.1 1.4 1 1 0 1 1 1 0 FR47-like protein Glyoxalase PF00903.25 KFM29063.1 - 4.8e-11 43.0 0.0 5e-08 33.2 0.0 2.6 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KFM29063.1 - 3.8e-08 33.6 0.0 2.6e-06 27.7 0.0 2.9 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ZZ PF00569.17 KFM29063.1 - 4.9e-07 29.5 5.7 8.4e-07 28.7 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 KFM29063.1 - 1.6e-06 28.2 0.0 3.1e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Glyoxalase_5 PF14696.6 KFM29063.1 - 0.0035 17.5 0.0 0.019 15.2 0.0 2.2 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 KFM29063.1 - 0.0038 17.4 4.3 0.017 15.2 0.4 3.6 3 2 0 3 3 3 1 Glyoxalase-like domain AlaDh_PNT_C PF01262.21 KFM29063.1 - 0.092 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KFM29063.1 - 0.14 11.2 0.2 0.24 10.5 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FBPase PF00316.20 KFM29064.1 - 3.7e-46 157.0 0.0 4.9e-46 156.6 0.0 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain SDA1 PF05285.12 KFM29066.1 - 4e-37 128.4 25.3 4e-37 128.4 25.3 2.1 2 1 0 2 2 2 1 SDA1 NUC130_3NT PF08158.12 KFM29066.1 - 3e-18 65.9 0.1 6.9e-18 64.7 0.1 1.7 1 0 0 1 1 1 1 NUC130/3NT domain PPTA PF01239.22 KFM29067.1 - 2.1e-20 71.8 0.0 1.4e-07 31.0 0.0 4.3 4 0 0 4 4 4 4 Protein prenyltransferase alpha subunit repeat DUF4219 PF13961.6 KFM29067.1 - 0.1 12.3 4.2 1.5 8.6 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) Methyltrans_SAM PF10672.9 KFM29068.1 - 1.5e-23 83.4 0.0 2.3e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase Methyltransf_31 PF13847.6 KFM29068.1 - 8.8e-10 38.6 0.0 1.4e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PUA_3 PF17785.1 KFM29068.1 - 1.1e-08 34.8 0.0 2.7e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 PUA-like domain MTS PF05175.14 KFM29068.1 - 1.7e-07 31.0 0.0 2.7e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KFM29068.1 - 3.1e-07 31.0 0.0 6.8e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KFM29068.1 - 5.4e-07 29.4 0.0 8.3e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PrmA PF06325.13 KFM29068.1 - 4.2e-06 26.4 0.0 6.7e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 KFM29068.1 - 0.00084 19.2 0.0 0.0024 17.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 KFM29068.1 - 0.015 15.1 0.0 0.023 14.5 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein FtsJ PF01728.19 KFM29068.1 - 0.016 15.3 0.0 0.027 14.6 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_11 PF08241.12 KFM29068.1 - 0.11 13.2 0.0 1.2 9.9 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_9 PF08003.11 KFM29068.1 - 0.12 11.2 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_15 PF09445.10 KFM29068.1 - 0.18 11.4 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Lactamase_B_3 PF13483.6 KFM29069.1 - 4.5e-21 75.4 0.0 7.3e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Pterin_bind PF00809.22 KFM29070.1 - 1.6e-76 257.2 0.0 2e-76 256.9 0.0 1.1 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 KFM29070.1 - 2.4e-25 89.2 0.0 4.5e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) PHF5 PF03660.14 KFM29071.1 - 1.4e-41 140.9 8.6 3.1e-41 139.8 8.6 1.5 1 1 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 KFM29071.1 - 0.0047 14.9 2.0 0.005 14.8 2.0 1.0 1 0 0 1 1 1 1 DNA polymerase II large subunit DP2 C1_2 PF03107.16 KFM29071.1 - 0.0055 17.0 11.1 0.25 11.7 3.2 2.4 1 1 1 2 2 2 2 C1 domain DZR PF12773.7 KFM29071.1 - 0.042 13.9 9.7 0.34 11.0 8.5 2.3 1 1 1 2 2 2 0 Double zinc ribbon zf-C6H2 PF15801.5 KFM29071.1 - 0.52 10.7 9.0 0.34 11.2 2.2 2.7 1 1 2 3 3 3 0 zf-MYND-like zinc finger, mRNA-binding zf-ribbon_3 PF13248.6 KFM29071.1 - 1 8.8 11.5 0.32 10.5 1.4 3.1 2 1 1 3 3 3 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 KFM29071.1 - 1.6 8.3 14.1 0.57 9.7 2.1 2.8 2 1 0 2 2 2 0 TFIIB zinc-binding Prok-RING_4 PF14447.6 KFM29071.1 - 1.8 8.5 12.7 10 6.1 0.5 3.3 1 1 2 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KFM29071.1 - 2.9 8.3 11.5 4.5e+02 1.3 11.5 2.8 1 1 0 1 1 1 0 Ring finger domain PHD PF00628.29 KFM29071.1 - 3.3 7.7 9.7 3.1 7.7 7.8 2.2 2 1 0 2 2 2 0 PHD-finger zn-ribbon_14 PF16503.5 KFM29071.1 - 4.5 6.9 10.9 0.13 11.8 0.9 2.8 3 0 0 3 3 3 0 Zinc-ribbon DUF2045 PF09741.9 KFM29072.1 - 5.2e-24 84.9 0.0 3.5e-19 69.1 0.0 2.1 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2045) tRNA-synt_1 PF00133.22 KFM29074.1 - 3e-200 666.5 0.0 6.2e-199 662.2 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KFM29074.1 - 3.4e-32 111.5 0.0 5.7e-32 110.8 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KFM29074.1 - 5.4e-23 81.4 0.0 3.8e-08 32.5 0.0 3.6 3 1 0 3 3 3 3 tRNA synthetases class I (M) Val_tRNA-synt_C PF10458.9 KFM29074.1 - 5.1e-15 55.5 5.9 1.1e-14 54.5 5.9 1.6 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1_2 PF13603.6 KFM29074.1 - 3.4e-09 36.5 0.0 2.3e-07 30.5 0.0 2.2 1 1 1 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 ABC_tran_CTD PF16326.5 KFM29074.1 - 9.7e-05 22.5 2.5 0.00032 20.9 2.5 2.0 1 0 0 1 1 1 1 ABC transporter C-terminal domain tRNA-synt_1e PF01406.19 KFM29074.1 - 0.00028 20.3 0.0 0.018 14.4 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 KFM29074.1 - 0.01 14.8 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (K) DivIC PF04977.15 KFM29074.1 - 2.6 7.9 6.4 0.59 9.9 0.1 2.7 3 0 0 3 3 3 0 Septum formation initiator PALP PF00291.25 KFM29075.1 - 1.7e-45 155.7 0.9 2.3e-45 155.3 0.9 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF1971 PF09313.11 KFM29075.1 - 0.18 11.8 0.0 0.37 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1971) MDM10 PF12519.8 KFM29075.1 - 0.32 9.8 0.0 0.46 9.3 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 PEPCK_ATP PF01293.20 KFM29076.1 - 1.3e-216 719.7 0.0 1.6e-216 719.5 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 KFM29076.1 - 0.069 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFM29076.1 - 0.087 13.2 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 KFM29076.1 - 0.13 11.8 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain FA_hydroxylase PF04116.13 KFM29078.1 - 2.9e-21 76.2 21.8 6.6e-21 75.0 21.8 1.6 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily BATS PF06968.13 KFM29079.1 - 2.5e-16 59.6 0.0 5e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 KFM29079.1 - 3.1e-14 53.7 0.0 4.7e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KFM29079.1 - 0.037 14.3 0.3 0.063 13.5 0.3 1.3 1 0 0 1 1 1 0 4Fe-4S single cluster domain Fer4_14 PF13394.6 KFM29079.1 - 0.039 14.1 0.1 0.092 12.9 0.1 1.6 1 0 0 1 1 1 0 4Fe-4S single cluster domain Ank_2 PF12796.7 KFM29080.1 - 2e-40 137.2 3.9 4.1e-20 72.2 0.3 2.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFM29080.1 - 7.9e-27 93.3 3.3 8.3e-14 51.8 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KFM29080.1 - 5.8e-22 77.1 1.1 1.4e-07 31.6 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 KFM29080.1 - 3.4e-20 70.0 0.1 4.3e-05 23.6 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KFM29080.1 - 9.3e-19 67.3 0.8 1.4e-09 38.0 0.0 3.7 1 1 3 4 4 4 3 Ankyrin repeats (many copies) PP2C PF00481.21 KFM29081.1 - 9.1e-50 169.7 0.0 2.6e-49 168.2 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C Lipase_3 PF01764.25 KFM29081.1 - 2.5e-20 72.8 0.0 6.3e-20 71.5 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) PP2C_2 PF13672.6 KFM29081.1 - 0.00045 19.9 0.0 0.002 17.8 0.0 2.1 2 1 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.12 KFM29081.1 - 0.087 12.7 1.5 0.32 10.9 0.2 2.5 3 0 0 3 3 3 0 Stage II sporulation protein E (SpoIIE) Abhydrolase_6 PF12697.7 KFM29081.1 - 0.19 12.3 2.3 0.53 10.8 0.0 2.7 3 1 0 3 3 3 0 Alpha/beta hydrolase family MTHFR PF02219.17 KFM29082.1 - 0.024 13.9 0.0 0.035 13.4 0.0 1.1 1 0 0 1 1 1 0 Methylenetetrahydrofolate reductase CPSase_L_D2 PF02786.17 KFM29084.1 - 3.6e-78 261.9 0.0 5.9e-78 261.2 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KFM29084.1 - 1.1e-43 148.3 0.9 2.1e-43 147.3 0.2 1.9 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KFM29084.1 - 9.8e-41 138.2 0.0 2.7e-40 136.8 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KFM29084.1 - 5.2e-16 58.2 0.2 1.2e-15 57.0 0.2 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KFM29084.1 - 1.6e-08 34.3 0.0 3.6e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KFM29084.1 - 4.4e-08 32.9 0.0 1.2e-07 31.4 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 KFM29084.1 - 5.7e-06 26.0 0.8 0.058 13.2 0.0 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.14 KFM29084.1 - 0.00045 20.3 0.0 0.00073 19.6 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 KFM29084.1 - 0.00067 20.3 1.8 0.59 10.9 0.1 2.6 2 0 0 2 2 2 2 HlyD family secretion protein ATP-grasp_5 PF13549.6 KFM29084.1 - 0.0018 17.8 0.0 0.0045 16.5 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 KFM29084.1 - 0.0093 15.2 0.0 0.057 12.7 0.0 1.9 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp HlyD_D23 PF16576.5 KFM29084.1 - 0.015 14.6 0.2 3.5 6.8 0.0 2.3 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion DUF2118 PF09891.9 KFM29084.1 - 0.017 15.1 0.2 0.038 13.9 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) RimK PF08443.11 KFM29084.1 - 0.041 13.5 0.0 0.19 11.3 0.0 2.0 1 1 0 1 1 1 0 RimK-like ATP-grasp domain GCV_H PF01597.19 KFM29084.1 - 0.16 11.9 0.6 0.65 9.9 0.1 2.0 2 0 0 2 2 2 0 Glycine cleavage H-protein DNA_pol_B PF00136.21 KFM29085.1 - 1.4e-138 462.4 0.0 1.9e-138 462.1 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KFM29085.1 - 1.3e-69 235.0 0.0 1.8e-69 234.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KFM29085.1 - 1e-18 67.5 7.9 1.9e-18 66.7 7.9 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo2 PF10108.9 KFM29085.1 - 0.023 14.4 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_B_2 PF03175.13 KFM29085.1 - 0.046 12.6 0.0 0.071 12.0 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral ETF_alpha PF00766.19 KFM29086.1 - 1.2e-35 121.4 0.4 2.9e-35 120.2 0.4 1.7 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.21 KFM29086.1 - 8.5e-31 107.2 4.6 8.5e-31 107.2 4.6 1.6 1 1 0 2 2 2 1 Electron transfer flavoprotein domain UPF0524 PF15823.5 KFM29087.1 - 0.054 12.9 0.0 0.062 12.7 0.0 1.1 1 0 0 1 1 1 0 UPF0524 of C3orf70 DUF2070 PF09843.9 KFM29088.1 - 0.7 8.1 2.9 0.87 7.8 2.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Alg6_Alg8 PF03155.15 KFM29089.1 - 3.3e-119 399.0 4.9 4.7e-119 398.5 4.9 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family ALG3 PF05208.13 KFM29089.1 - 0.11 11.9 0.6 0.22 10.9 0.6 1.5 1 0 0 1 1 1 0 ALG3 protein Histidinol_dh PF00815.20 KFM29090.1 - 4.4e-153 510.1 1.4 5e-153 509.9 1.4 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase RNA_pol_N PF01194.17 KFM29091.1 - 1.3e-32 111.8 0.7 1.5e-32 111.7 0.7 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit DNA_pol_E_B PF04042.16 KFM29092.1 - 1.9e-12 47.0 0.0 7.9e-12 45.0 0.0 1.7 1 1 1 2 2 2 1 DNA polymerase alpha/epsilon subunit B Sugarporin_N PF11471.8 KFM29092.1 - 0.022 14.7 0.4 0.022 14.7 0.4 1.9 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Gly-rich_Ago1 PF12764.7 KFM29092.1 - 0.097 13.5 2.6 0.2 12.5 2.6 1.5 1 0 0 1 1 1 0 Glycine-rich region of argonaut CDC48_N PF02359.18 KFM29092.1 - 0.2 11.8 0.0 0.4 10.9 0.0 1.4 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain Glyco_transf_22 PF03901.17 KFM29094.1 - 1.8e-76 258.1 4.6 2.2e-76 257.8 4.6 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family RRM_1 PF00076.22 KFM29095.1 - 1.1e-23 82.8 0.0 2e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pur_ac_phosph_N PF16656.5 KFM29095.1 - 5e-17 62.3 0.0 1e-16 61.3 0.0 1.4 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain fn3_PAP PF17808.1 KFM29095.1 - 3.5e-15 56.1 0.0 3.3e-14 53.0 0.0 2.3 1 1 0 1 1 1 1 Fn3-like domain from Purple Acid Phosphatase Metallophos PF00149.28 KFM29095.1 - 7.7e-12 46.1 0.1 1.5e-11 45.2 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase CSTF2_hinge PF14327.6 KFM29095.1 - 7.3e-10 39.2 0.5 2.4e-09 37.5 0.0 2.0 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF_C PF14304.6 KFM29095.1 - 2.4e-07 30.2 12.7 2.4e-07 30.2 12.7 1.6 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal partial_CstF PF15861.5 KFM29095.1 - 0.031 14.0 1.2 0.063 13.1 1.2 1.4 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain Gpr1_Fun34_YaaH PF01184.19 KFM29096.1 - 3.3e-15 56.3 25.0 7.3e-15 55.1 25.0 1.4 1 1 0 1 1 1 1 GPR1/FUN34/yaaH family DUF1600 PF07667.11 KFM29096.1 - 3.3 8.0 7.0 30 4.9 7.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1600) Hydantoinase_B PF02538.14 KFM29097.1 - 1.1e-193 644.4 7.7 3.8e-193 642.6 7.7 1.8 1 1 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KFM29097.1 - 2.5e-74 250.1 1.9 4.9e-72 242.7 1.9 2.8 1 1 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KFM29097.1 - 2.8e-52 177.0 0.1 1.6e-50 171.3 0.0 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region SIR2 PF02146.17 KFM29097.1 - 1.6e-48 165.0 0.0 2.3e-48 164.5 0.0 1.3 1 0 0 1 1 1 1 Sir2 family Myb_DNA-binding PF00249.31 KFM29098.1 - 2.2e-09 37.4 0.0 3.7e-07 30.2 0.1 2.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KFM29098.1 - 3.2e-07 30.1 1.7 2.6e-06 27.3 0.5 2.2 2 0 0 2 2 2 1 Myb DNA-binding like Hist_deacetyl PF00850.19 KFM29099.1 - 2e-77 260.7 0.0 2.4e-77 260.4 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain WAPL PF07814.13 KFM29101.1 - 4.9e-11 42.0 0.1 2.1e-07 30.1 0.0 2.1 2 0 0 2 2 2 2 Wings apart-like protein regulation of heterochromatin MMS1_N PF10433.9 KFM29102.1 - 6.4e-86 288.9 0.0 9.8e-86 288.3 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KFM29102.1 - 6.1e-71 239.4 0.0 1e-70 238.6 0.0 1.4 1 0 0 1 1 1 1 CPSF A subunit region ALF PF03752.13 KFM29103.1 - 0.013 15.4 4.7 0.034 14.1 0.1 2.9 2 0 0 2 2 2 0 Short repeats of unknown function CCT PF06203.14 KFM29104.1 - 1.7e-16 60.0 9.8 2.2e-16 59.6 9.8 1.2 1 0 0 1 1 1 1 CCT motif EPL1 PF10513.9 KFM29105.1 - 2.7e-10 40.8 0.0 7.3e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Enhancer of polycomb-like CorA PF01544.18 KFM29106.1 - 0.11 11.8 2.1 0.17 11.2 0.1 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein FbpA PF05833.11 KFM29106.1 - 0.13 11.0 1.6 2.3 6.9 0.0 2.3 2 0 0 2 2 2 0 Fibronectin-binding protein A N-terminus (FbpA) SMN PF06003.12 KFM29106.1 - 0.22 10.8 0.7 0.31 10.3 0.7 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Acyl-CoA_dh_1 PF00441.24 KFM29107.1 - 8.4e-29 100.7 4.5 1.3e-28 100.1 4.5 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KFM29107.1 - 4.8e-23 82.0 0.4 3.9e-22 79.0 0.0 2.5 2 1 1 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KFM29107.1 - 6.3e-21 74.4 0.0 1.2e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFM29107.1 - 1.5e-06 28.5 2.1 1.7e-06 28.3 1.1 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Metallophos PF00149.28 KFM29108.1 - 5.5e-33 115.2 0.0 1.3e-32 114.0 0.0 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Kelch_1 PF01344.25 KFM29108.1 - 3.6e-11 42.5 2.7 0.002 17.7 0.0 5.5 6 1 0 6 6 6 3 Kelch motif Kelch_3 PF13415.6 KFM29108.1 - 1.5e-10 41.1 10.1 0.001 19.3 0.1 5.2 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.6 KFM29108.1 - 1.5e-10 40.8 0.0 0.019 15.0 0.0 4.8 4 1 0 4 4 4 4 Kelch motif Kelch_4 PF13418.6 KFM29108.1 - 3.3e-09 36.6 9.8 0.0062 16.5 0.0 5.9 6 1 0 6 6 6 2 Galactose oxidase, central domain Kelch_6 PF13964.6 KFM29108.1 - 2e-05 24.7 2.6 1.8 9.0 0.0 5.8 5 1 1 6 6 6 2 Kelch motif Kelch_2 PF07646.15 KFM29108.1 - 8.8e-05 22.3 1.4 2.3 8.3 0.0 5.0 4 1 1 5 5 5 1 Kelch motif STPPase_N PF16891.5 KFM29108.1 - 0.0002 21.7 0.0 0.00038 20.8 0.0 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain PfkB PF00294.24 KFM29109.1 - 3.5e-29 102.0 3.0 5.3e-13 48.9 0.0 3.0 2 1 1 3 3 3 3 pfkB family carbohydrate kinase DUF5585 PF17823.1 KFM29109.1 - 0.077 11.9 0.9 0.12 11.3 0.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5585) LTV PF04180.14 KFM29110.1 - 1.3e-11 44.8 1.9 9.7e-05 22.3 2.7 2.8 2 1 0 2 2 2 2 Low temperature viability protein FHA PF00498.26 KFM29111.1 - 2.8e-06 27.6 0.0 4.3e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KFM29111.1 - 9.9e-05 22.6 0.0 0.00046 20.5 0.0 1.9 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain DIOX_N PF14226.6 KFM29113.1 - 2.6e-31 108.8 0.0 4.3e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Xan_ur_permease PF00860.20 KFM29113.1 - 6.6e-27 94.2 32.7 2.5e-16 59.4 12.3 2.3 2 0 0 2 2 2 2 Permease family 2OG-FeII_Oxy PF03171.20 KFM29113.1 - 6.5e-21 74.7 0.0 1.4e-20 73.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AP2 PF00847.20 KFM29114.1 - 8.3e-06 25.9 0.8 1e-05 25.6 0.0 1.5 2 0 0 2 2 2 1 AP2 domain Hydrolase_4 PF12146.8 KFM29115.1 - 1.5e-11 44.0 0.0 3.3e-11 42.9 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFM29115.1 - 2.3e-11 43.9 0.0 1.1e-10 41.6 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFM29115.1 - 2.3e-10 41.5 8.0 2.3e-10 41.5 8.0 2.6 3 0 0 3 3 3 1 Alpha/beta hydrolase family DAGAT PF03982.13 KFM29115.1 - 4.3e-06 25.9 0.0 6.4e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Thioesterase PF00975.20 KFM29115.1 - 0.022 14.9 0.3 0.15 12.1 0.2 2.3 3 0 0 3 3 3 0 Thioesterase domain Acyltransferase PF01553.21 KFM29115.1 - 0.058 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Acyltransferase Abhydrolase_3 PF07859.13 KFM29115.1 - 0.087 12.7 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.20 KFM29115.1 - 0.12 12.0 0.1 0.18 11.4 0.1 1.2 1 0 0 1 1 1 0 Putative esterase DUF2920 PF11144.8 KFM29115.1 - 0.27 10.4 0.0 0.39 9.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Tim17 PF02466.19 KFM29117.1 - 0.00026 21.3 4.7 0.0018 18.7 4.7 2.1 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF533 PF04391.12 KFM29117.1 - 0.054 13.1 2.7 0.13 11.9 2.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF533) HTH_15 PF12324.8 KFM29117.1 - 0.07 13.1 0.6 0.37 10.8 0.0 2.2 3 0 0 3 3 3 0 Helix-turn-helix domain of alkylmercury lyase Baculo_PEP_C PF04513.12 KFM29118.1 - 1.4e-05 25.2 2.4 0.008 16.2 0.3 2.2 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus COG5 PF10392.9 KFM29118.1 - 0.018 15.2 0.8 1.8 8.7 0.1 2.2 2 0 0 2 2 2 0 Golgi transport complex subunit 5 NPV_P10 PF05531.12 KFM29118.1 - 0.068 13.6 2.8 7.5 7.1 0.1 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein ApoLp-III PF07464.11 KFM29118.1 - 0.09 12.9 0.3 1.1 9.3 0.1 2.1 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) SIP1 PF04938.12 KFM29120.1 - 2.3e-21 76.5 0.0 2.1e-19 70.1 0.0 2.0 1 1 1 2 2 2 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) Inositol_P PF00459.25 KFM29121.1 - 4.7e-58 196.9 0.1 7.1e-58 196.3 0.1 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family Pectate_lyase_3 PF12708.7 KFM29122.1 - 2.6e-09 37.3 7.1 2.9e-09 37.1 0.5 2.3 2 0 0 2 2 2 2 Pectate lyase superfamily protein Pectate_lyase_3 PF12708.7 KFM29123.1 - 6.6e-13 49.0 2.7 5.7e-06 26.3 0.3 2.7 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KFM29123.1 - 0.00032 20.3 1.8 0.3 10.8 0.1 4.0 4 0 0 4 4 4 2 N terminal extension of bacteriophage endosialidase Staygreen PF12638.7 KFM29124.1 - 1.1e-34 119.3 0.0 2e-34 118.5 0.0 1.4 1 1 0 1 1 1 1 Staygreen protein RL10P_insert PF17777.1 KFM29126.1 - 5.2e-21 74.4 0.0 1.2e-20 73.3 0.0 1.6 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 KFM29126.1 - 1.4e-18 66.9 0.0 2.2e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 Cpn60_TCP1 PF00118.24 KFM29128.1 - 2e-120 402.7 0.0 1.5e-94 317.4 0.0 2.1 1 1 1 2 2 2 2 TCP-1/cpn60 chaperonin family CCT PF06203.14 KFM29129.1 - 5.1e-17 61.7 13.2 7.7e-17 61.1 13.2 1.3 1 0 0 1 1 1 1 CCT motif Cellulase PF00150.18 KFM29130.1 - 1.5e-11 44.3 1.2 3.1e-11 43.2 1.2 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 KFM29130.1 - 1e-05 25.1 0.3 0.00018 21.0 0.2 2.2 2 0 0 2 2 2 1 Beta-galactosidase DUF3040 PF11239.8 KFM29131.1 - 0.44 10.9 2.7 1.7 9.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Herpes_UL55 PF04537.12 KFM29132.1 - 0.093 12.7 0.1 0.15 12.1 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus UL55 protein GATase_2 PF00310.21 KFM29133.1 - 7.4e-157 522.4 0.0 9.2e-157 522.1 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 KFM29133.1 - 2.6e-134 448.0 0.9 1e-133 446.0 0.1 2.3 2 1 0 2 2 2 1 Conserved region in glutamate synthase GXGXG PF01493.19 KFM29133.1 - 6.2e-73 244.5 4.5 1.3e-72 243.4 4.5 1.5 1 0 0 1 1 1 1 GXGXG motif Glu_syn_central PF04898.14 KFM29133.1 - 3.9e-66 223.4 0.3 4.4e-33 115.0 0.0 3.1 2 1 1 3 3 3 2 Glutamate synthase central domain FMN_dh PF01070.18 KFM29133.1 - 0.00095 18.3 7.9 0.0017 17.4 7.9 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase UDG PF03167.19 KFM29134.1 - 1.5e-21 77.0 0.0 2.6e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily KH_8 PF17903.1 KFM29135.1 - 0.00022 21.3 0.0 0.0004 20.4 0.0 1.4 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KFM29135.1 - 0.0033 17.2 0.3 0.0072 16.1 0.3 1.5 1 0 0 1 1 1 1 KH domain RRM_1 PF00076.22 KFM29136.1 - 6.7e-31 105.9 0.5 1.5e-18 66.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFM29136.1 - 1.5e-06 28.3 0.1 2.6e-05 24.2 0.0 2.3 1 1 1 2 2 2 1 RNA recognition motif Nup35_RRM_2 PF14605.6 KFM29136.1 - 7e-05 22.8 0.1 0.037 14.0 0.1 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 KFM29136.1 - 7.2e-05 23.1 0.2 0.068 13.4 0.1 2.6 1 1 1 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter OB_RNB PF08206.11 KFM29136.1 - 0.036 13.7 0.3 4.1 7.2 0.0 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain Ribosomal_L14 PF00238.19 KFM29136.1 - 0.17 11.9 0.3 0.31 11.1 0.1 1.5 2 0 0 2 2 2 0 Ribosomal protein L14p/L23e MatE PF01554.18 KFM29137.1 - 2.4e-41 141.1 21.0 1.6e-22 79.9 9.9 3.3 2 1 1 3 3 3 3 MatE Pentapeptide PF00805.22 KFM29138.1 - 4.8e-17 61.3 5.7 1.7e-08 33.9 0.9 3.7 2 1 1 4 4 4 3 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 KFM29138.1 - 8.1e-12 45.1 0.0 5.7e-07 29.6 0.0 2.0 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 KFM29138.1 - 1.1e-08 35.1 0.0 0.13 12.4 0.0 3.2 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) LolA_like PF17131.4 KFM29138.1 - 0.053 13.2 0.1 9.5 5.9 0.0 2.2 2 0 0 2 2 2 0 Outer membrane lipoprotein-sorting protein Solute_trans_a PF03619.16 KFM29139.1 - 2.2e-41 142.2 0.1 3.2e-41 141.6 0.1 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF4231 PF14015.6 KFM29139.1 - 0.054 14.0 0.3 0.1 13.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Aa_trans PF01490.18 KFM29140.1 - 1.1e-27 96.8 32.0 4e-27 95.0 32.0 1.8 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein PMT_4TMC PF16192.5 KFM29140.1 - 4.4 6.8 6.2 5.2 6.6 0.3 3.1 2 1 1 3 3 3 0 C-terminal four TMM region of protein-O-mannosyltransferase SGS PF05002.15 KFM29141.1 - 1.9e-24 85.6 2.2 3.7e-24 84.6 2.2 1.5 1 0 0 1 1 1 1 SGS domain CS PF04969.16 KFM29141.1 - 4.9e-14 53.1 0.0 2.1e-13 51.1 0.0 2.0 2 0 0 2 2 2 1 CS domain TPR_2 PF07719.17 KFM29141.1 - 5.5e-07 29.2 1.0 0.011 15.8 0.1 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFM29141.1 - 4.5e-05 23.1 0.4 0.03 14.1 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFM29141.1 - 0.0018 18.4 2.5 0.071 13.3 0.3 2.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFM29141.1 - 0.0021 18.6 3.5 0.0062 17.2 3.5 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat Pentapeptide_2 PF01469.18 KFM29141.1 - 0.012 15.5 17.7 0.037 13.9 17.6 1.8 1 1 0 1 1 1 0 Pentapeptide repeats (8 copies) TPR_14 PF13428.6 KFM29141.1 - 0.028 15.2 3.1 0.31 12.0 0.7 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFM29141.1 - 0.22 11.8 0.5 11 6.6 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DHC_N1 PF08385.12 KFM29142.1 - 1.4e-18 66.9 0.0 1.6e-13 50.2 0.0 2.1 1 1 1 2 2 2 2 Dynein heavy chain, N-terminal region 1 CBFD_NFYB_HMF PF00808.23 KFM29143.1 - 6.3e-14 52.0 0.0 7.5e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFM29143.1 - 1.2e-08 35.4 0.0 1.5e-08 35.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 KFM29143.1 - 3.2e-06 27.1 0.0 4.2e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Bromodomain associated Importin_rep_5 PF18816.1 KFM29143.1 - 0.085 13.2 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Importin repeat CENP-T_C PF15511.6 KFM29143.1 - 0.13 12.4 0.0 0.18 11.9 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold HECT PF00632.25 KFM29144.1 - 2e-65 221.3 0.0 2.9e-65 220.8 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RCC1 PF00415.18 KFM29144.1 - 3.9e-41 139.4 8.9 2.3e-11 44.1 0.0 4.7 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFM29144.1 - 6.7e-17 60.8 28.3 2.6e-05 23.9 0.6 5.3 5 1 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat Ribosomal_S4e PF00900.20 KFM29145.1 - 1.2e-36 124.5 0.4 4.2e-36 122.7 0.1 2.0 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 KFM29145.1 - 6.8e-22 76.9 0.0 1.6e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 KFM29145.1 - 8e-21 73.9 6.8 1.5e-20 73.0 6.8 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 KFM29145.1 - 2.5e-07 30.3 0.0 4.6e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 KFM29145.1 - 3.2e-05 23.7 4.0 5.4e-05 23.0 1.5 2.7 3 0 0 3 3 3 1 KOW motif HARE-HTH PF05066.13 KFM29146.1 - 0.00072 19.9 0.0 0.0012 19.2 0.0 1.3 1 0 0 1 1 1 1 HB1, ASXL, restriction endonuclease HTH domain La PF05383.17 KFM29147.1 - 2.1e-17 62.9 0.0 3.9e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 La domain Erv26 PF04148.13 KFM29149.1 - 5.5e-29 101.5 1.6 4.8e-28 98.4 1.6 1.9 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 Metallophos PF00149.28 KFM29150.1 - 1.3e-06 29.0 0.0 1.6e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFM29150.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Peptidase_M41 PF01434.18 KFM29151.1 - 8.6e-54 182.3 2.0 2.2e-53 181.0 2.0 1.6 1 1 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KFM29151.1 - 1.5e-42 145.2 0.0 2.8e-42 144.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PFK PF00365.20 KFM29151.1 - 6.8e-40 137.2 0.0 1.4e-39 136.2 0.0 1.4 1 0 0 1 1 1 1 Phosphofructokinase AAA_lid_3 PF17862.1 KFM29151.1 - 4.8e-11 42.3 0.5 1.3e-10 40.9 0.5 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KFM29151.1 - 2.4e-06 27.6 0.0 5.6e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KFM29151.1 - 1.8e-05 24.5 0.0 6.1e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KFM29151.1 - 0.00023 20.5 0.0 0.00044 19.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 KFM29151.1 - 0.0034 17.6 0.1 0.077 13.3 0.1 2.6 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KFM29151.1 - 0.0041 16.5 0.3 0.0083 15.5 0.3 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KFM29151.1 - 0.005 16.6 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 KFM29151.1 - 0.0055 16.9 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFM29151.1 - 0.006 17.0 0.1 0.006 17.0 0.1 3.5 3 2 1 4 4 3 1 AAA ATPase domain AAA_7 PF12775.7 KFM29151.1 - 0.026 14.0 0.0 0.078 12.5 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 KFM29151.1 - 0.046 13.6 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 KFM29151.1 - 0.053 14.1 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 KFM29151.1 - 0.056 13.6 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) TsaE PF02367.17 KFM29151.1 - 0.08 12.9 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KFM29151.1 - 0.084 13.1 0.0 0.084 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KFM29151.1 - 0.089 13.2 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFM29151.1 - 0.14 12.7 0.4 0.49 10.9 0.2 1.9 2 0 0 2 2 2 0 ABC transporter Zeta_toxin PF06414.12 KFM29151.1 - 0.23 10.7 0.3 0.5 9.6 0.3 1.5 1 0 0 1 1 1 0 Zeta toxin Aminotran_5 PF00266.19 KFM29152.1 - 5.2e-20 71.7 0.0 6.4e-15 55.0 0.0 2.7 2 1 1 3 3 3 2 Aminotransferase class-V ShK PF01549.24 KFM29154.1 - 0.00018 22.0 7.8 0.0013 19.2 7.8 2.2 1 1 0 1 1 1 1 ShK domain-like DUF829 PF05705.14 KFM29155.1 - 2e-36 126.1 0.0 2.3e-36 125.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) EamA PF00892.20 KFM29156.1 - 0.0025 18.0 4.2 0.0025 18.0 4.2 3.5 1 1 2 3 3 3 2 EamA-like transporter family PCI PF01399.27 KFM29157.1 - 3.3e-10 40.4 0.0 8.7e-10 39.0 0.0 1.7 2 0 0 2 2 2 1 PCI domain ComFB PF10719.9 KFM29157.1 - 0.0025 17.9 0.0 0.0059 16.7 0.0 1.6 1 0 0 1 1 1 1 Late competence development protein ComFB zf-CCCH_6 PF18585.1 KFM29157.1 - 0.082 12.8 0.4 1.7 8.6 0.0 2.5 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 PrmA PF06325.13 KFM29158.1 - 9.2e-13 48.2 5.4 3.2e-08 33.3 1.3 2.2 2 0 0 2 2 2 2 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KFM29158.1 - 4.4e-08 32.9 1.6 0.0028 17.2 0.5 2.3 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_25 PF13649.6 KFM29158.1 - 4.5e-08 33.7 1.3 6.4e-05 23.6 0.4 3.1 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 KFM29158.1 - 6.5e-05 22.8 0.1 0.0035 17.1 0.1 2.4 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KFM29158.1 - 0.00016 21.4 1.7 0.056 13.1 0.1 2.3 2 0 0 2 2 2 2 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 KFM29158.1 - 0.00049 20.7 0.4 0.039 14.6 0.1 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM29158.1 - 0.0011 18.8 0.1 0.012 15.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.16 KFM29158.1 - 0.0021 17.9 0.2 0.031 14.0 0.0 2.4 3 0 0 3 3 3 1 Met-10+ like-protein PCMT PF01135.19 KFM29158.1 - 0.0098 15.7 0.6 0.12 12.1 0.1 2.1 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GCD14 PF08704.10 KFM29158.1 - 0.012 15.3 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_18 PF12847.7 KFM29158.1 - 0.051 13.5 0.1 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain TPR_2 PF07719.17 KFM29158.1 - 0.061 13.5 0.0 0.28 11.4 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat Methyltransf_32 PF13679.6 KFM29158.1 - 0.066 13.2 0.2 3.1 7.8 0.1 2.3 2 0 0 2 2 2 0 Methyltransferase domain CMAS PF02353.20 KFM29158.1 - 0.18 11.0 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Glyco_transf_90 PF05686.12 KFM29159.1 - 6.8e-29 101.0 0.0 1.1e-28 100.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_transf_90 PF05686.12 KFM29161.1 - 5.1e-25 88.2 0.0 9.3e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 90 TamB PF04357.13 KFM29162.1 - 0.00036 19.9 0.1 0.014 14.7 0.0 3.3 4 0 0 4 4 4 1 TamB, inner membrane protein subunit of TAM complex DUF3971 PF13116.6 KFM29162.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function Fer2 PF00111.27 KFM29163.1 - 5e-13 48.8 0.3 8.2e-13 48.1 0.3 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Abhydrolase_6 PF12697.7 KFM29164.1 - 6.6e-29 102.1 12.8 1.2e-28 101.2 12.8 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFM29164.1 - 2e-20 73.5 0.0 2.6e-17 63.3 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFM29164.1 - 7.5e-18 64.7 0.0 1e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KFM29164.1 - 0.0075 16.4 0.1 0.011 15.8 0.1 1.3 1 0 0 1 1 1 1 Thioesterase domain DLH PF01738.18 KFM29164.1 - 0.016 14.8 0.0 8.1 5.9 0.0 2.6 2 1 1 3 3 3 0 Dienelactone hydrolase family Abhydrolase_4 PF08386.10 KFM29164.1 - 0.11 12.6 0.0 0.54 10.4 0.0 2.1 2 0 0 2 2 2 0 TAP-like protein RRM_1 PF00076.22 KFM29165.1 - 7.2e-20 70.6 0.1 7.9e-09 35.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFM29165.1 - 1.4e-05 25.1 0.3 0.013 15.6 0.1 2.8 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KFM29165.1 - 0.0045 17.0 0.0 1.7 8.7 0.0 2.2 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 KFM29165.1 - 0.067 13.4 0.0 14 5.9 0.0 2.3 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter RL PF17797.1 KFM29165.1 - 0.23 11.4 0.1 5.3 7.1 0.0 2.2 2 0 0 2 2 2 0 RL domain Ferric_reduct PF01794.19 KFM29166.1 - 2.5e-17 63.1 7.6 2.5e-17 63.1 7.6 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KFM29166.1 - 1.9e-07 31.1 0.0 6.1e-07 29.5 0.0 1.8 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.12 KFM29166.1 - 2.5e-05 24.4 0.0 0.0091 16.1 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain MIG-14_Wnt-bd PF06664.12 KFM29166.1 - 0.058 12.6 4.2 0.045 13.0 2.7 1.5 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion Ferric_reduct PF01794.19 KFM29167.1 - 4.4e-16 59.1 11.7 4.4e-16 59.1 11.7 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KFM29167.1 - 1e-05 25.5 0.0 1.9e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KFM29169.1 - 5.4e-14 52.4 16.0 5.4e-14 52.4 16.0 2.5 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KFM29169.1 - 2.8e-10 40.2 0.0 5.1e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KFM29169.1 - 2.8e-08 34.0 0.0 1.3e-07 31.9 0.0 1.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KFM29170.1 - 6e-14 52.2 18.5 6e-14 52.2 18.5 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KFM29170.1 - 3.3e-10 40.0 0.0 6.6e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KFM29170.1 - 2.4e-08 34.3 0.0 3.1e-07 30.7 0.0 2.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KFM29171.1 - 3.9e-15 56.1 16.3 1e-14 54.7 16.3 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KFM29171.1 - 1.5e-09 37.9 0.0 2.3e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KFM29171.1 - 0.0026 17.9 0.0 0.019 15.1 0.0 2.0 2 0 0 2 2 2 1 Ferric reductase NAD binding domain NAD_binding_6 PF08030.12 KFM29172.1 - 0.0061 16.7 0.0 0.0095 16.1 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Methyltransf_11 PF08241.12 KFM29173.1 - 3.9e-23 81.9 0.0 7.1e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFM29173.1 - 4.3e-21 75.4 0.0 8.7e-21 74.5 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM29173.1 - 1.1e-16 61.2 0.0 1.3e-16 60.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM29173.1 - 8.1e-15 55.4 0.0 1.2e-14 54.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFM29173.1 - 7.2e-13 48.4 0.0 9.4e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KFM29173.1 - 1.3e-12 47.8 0.0 1.8e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 KFM29173.1 - 0.0036 15.9 0.0 0.0048 15.5 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_8 PF05148.15 KFM29173.1 - 0.076 12.8 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Hypothetical methyltransferase MetW PF07021.12 KFM29173.1 - 0.14 11.8 0.0 0.32 10.5 0.0 1.7 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_33 PF10017.9 KFM29173.1 - 0.16 11.1 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Pkinase PF00069.25 KFM29174.1 - 8e-56 189.3 0.0 9.4e-43 146.5 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain EF-hand_1 PF00036.32 KFM29174.1 - 1.4e-30 102.5 3.4 1.8e-07 30.2 0.1 4.7 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 KFM29174.1 - 1.2e-26 90.3 0.1 4.7e-07 29.2 0.0 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 KFM29174.1 - 1.2e-26 92.9 0.0 2e-12 47.4 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KFM29174.1 - 4.8e-23 80.8 2.2 4.9e-13 48.7 0.1 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 KFM29174.1 - 6.4e-23 79.2 0.1 1.8e-06 27.1 0.0 4.5 4 0 0 4 4 4 4 EF hand Pkinase_Tyr PF07714.17 KFM29174.1 - 1.3e-19 70.6 0.0 1.9e-12 47.1 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase EF-hand_9 PF14658.6 KFM29174.1 - 1.5e-09 38.1 0.0 0.0017 18.6 0.0 2.7 3 0 0 3 3 2 2 EF-hand domain EF-hand_11 PF08976.11 KFM29174.1 - 2e-08 35.0 0.0 0.0086 16.9 0.0 2.4 1 1 1 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KFM29174.1 - 1.3e-05 25.1 0.0 0.077 12.9 0.0 2.5 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Kdo PF06293.14 KFM29174.1 - 0.0015 17.9 0.9 0.003 17.0 0.1 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFM29174.1 - 0.0015 17.9 0.0 0.026 13.9 0.0 2.2 1 1 1 2 2 2 1 Kinase-like PMBR PF09373.10 KFM29174.1 - 0.0052 16.9 0.2 6.7 7.1 0.0 3.9 4 0 0 4 4 4 1 Pseudomurein-binding repeat APH PF01636.23 KFM29174.1 - 0.041 13.8 0.7 0.59 10.0 0.2 2.5 2 1 0 2 2 2 0 Phosphotransferase enzyme family SPARC_Ca_bdg PF10591.9 KFM29174.1 - 0.046 14.1 0.0 0.3 11.4 0.0 2.1 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region FabA PF07977.13 KFM29175.1 - 2.8e-28 98.3 0.0 3.1e-28 98.1 0.0 1.0 1 0 0 1 1 1 1 FabA-like domain MaoC_dehydratas PF01575.19 KFM29175.1 - 0.042 13.4 0.1 0.058 13.0 0.1 1.2 1 0 0 1 1 1 0 MaoC like domain Imm42 PF15593.6 KFM29175.1 - 0.11 12.9 0.0 0.16 12.4 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 42 DUF707 PF05212.12 KFM29176.1 - 0.0007 18.9 0.0 0.017 14.4 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF707) Glyco_transf_64 PF09258.10 KFM29176.1 - 0.0055 16.0 0.0 0.012 14.9 0.1 1.4 2 0 0 2 2 2 1 Glycosyl transferase family 64 domain Glyco_transf_21 PF13506.6 KFM29176.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 LRR_8 PF13855.6 KFM29177.1 - 1.3e-21 76.2 0.2 4.1e-09 36.1 0.0 3.4 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFM29177.1 - 3.2e-18 65.5 0.9 6.9e-05 23.1 0.1 4.9 3 2 3 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFM29177.1 - 4.8e-07 29.4 1.5 25 5.9 0.1 6.4 7 0 0 7 7 7 1 Leucine Rich Repeat LRR_6 PF13516.6 KFM29177.1 - 8.8e-05 22.3 10.3 3.3 8.0 0.5 6.1 6 0 0 6 6 6 2 Leucine Rich repeat LRR_9 PF14580.6 KFM29177.1 - 0.0033 16.9 0.2 0.012 15.1 0.1 1.9 1 1 0 2 2 2 1 Leucine-rich repeat LRR_2 PF07723.13 KFM29177.1 - 0.011 16.3 0.2 1.9 9.3 0.0 3.6 3 0 0 3 3 3 0 Leucine Rich Repeat UPF0731 PF14982.6 KFM29177.1 - 0.11 12.6 0.0 0.32 11.2 0.0 1.7 1 0 0 1 1 1 0 UPF0731 family DUF707 PF05212.12 KFM29178.1 - 0.00067 19.0 0.0 0.13 11.5 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF707) ACC_epsilon PF13822.6 KFM29178.1 - 0.014 16.0 3.6 0.25 12.1 0.3 2.5 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit Glyco_transf_21 PF13506.6 KFM29178.1 - 0.047 13.2 0.0 0.081 12.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 21 DUF707 PF05212.12 KFM29179.1 - 1.3e-05 24.6 0.0 0.00015 21.2 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF707) adh_short_C2 PF13561.6 KFM29180.1 - 5.3e-55 186.5 0.1 6.9e-55 186.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFM29180.1 - 6.9e-48 162.7 0.5 8.4e-48 162.4 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFM29180.1 - 3.4e-10 40.1 0.6 4.8e-10 39.6 0.6 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KFM29180.1 - 0.043 13.2 0.1 0.07 12.5 0.1 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) cpYpsA PF12694.7 KFM29180.1 - 0.051 13.4 0.1 0.083 12.7 0.1 1.3 1 0 0 1 1 1 0 Circularly permutated YpsA SLOG family Polysacc_synt_2 PF02719.15 KFM29180.1 - 0.063 12.4 0.4 0.083 12.0 0.4 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Caerin_1 PF07440.12 KFM29180.1 - 0.4 10.8 2.0 0.84 9.8 2.0 1.4 1 0 0 1 1 1 0 Caerin 1 protein GATA PF00320.27 KFM29181.1 - 0.0068 16.0 6.5 0.019 14.6 6.5 1.8 1 0 0 1 1 1 1 GATA zinc finger Med26 PF08711.11 KFM29181.1 - 0.032 14.2 0.0 0.054 13.5 0.0 1.3 1 0 0 1 1 1 0 TFIIS helical bundle-like domain DUF4515 PF14988.6 KFM29182.1 - 0.0012 18.7 2.8 0.0012 18.7 2.8 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4515) TACC_C PF05010.14 KFM29182.1 - 0.0033 17.3 6.5 1.4 8.7 1.2 3.1 1 1 2 3 3 3 3 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Filament PF00038.21 KFM29182.1 - 0.11 12.1 17.6 0.072 12.7 1.9 3.1 1 1 1 3 3 3 0 Intermediate filament protein Fez1 PF06818.15 KFM29182.1 - 0.15 12.5 17.1 0.13 12.7 1.9 2.1 1 1 1 2 2 2 0 Fez1 COG2 PF06148.11 KFM29182.1 - 3.4 7.8 9.4 0.65 10.1 1.7 3.1 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Mlo PF03094.15 KFM29183.1 - 1.5e-41 142.3 17.4 2e-16 59.4 10.7 3.1 3 0 0 3 3 3 3 Mlo family Sporozoite_P67 PF05642.11 KFM29183.1 - 9 4.2 9.3 13 3.7 9.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen adh_short PF00106.25 KFM29184.1 - 3.3e-54 183.3 3.1 4.2e-54 183.0 3.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM29184.1 - 6e-54 183.1 3.9 1.2e-53 182.1 3.9 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM29184.1 - 9.2e-09 35.5 1.4 1.5e-08 34.8 1.4 1.2 1 0 0 1 1 1 1 KR domain LT-IIB PF06453.11 KFM29184.1 - 0.033 14.1 0.1 0.095 12.6 0.0 1.8 2 1 1 3 3 3 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) Epimerase PF01370.21 KFM29184.1 - 0.11 12.0 0.3 0.17 11.3 0.3 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Calmodulin_bind PF07887.11 KFM29185.1 - 0.0011 18.3 0.0 0.0081 15.5 0.0 2.2 1 1 0 1 1 1 1 Calmodulin binding protein-like HSP20 PF00011.21 KFM29186.1 - 1.3e-19 70.2 0.0 1.6e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KFM29186.1 - 3.1e-10 39.4 0.0 5.4e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA CS PF04969.16 KFM29186.1 - 0.007 17.4 0.0 0.0093 17.0 0.0 1.2 1 0 0 1 1 1 1 CS domain Thiol_cytolysin PF01289.19 KFM29186.1 - 0.05 12.5 0.0 0.069 12.0 0.0 1.1 1 0 0 1 1 1 0 Thiol-activated cytolysin ORC3_N PF07034.11 KFM29187.1 - 2.9e-31 108.8 0.0 3e-30 105.5 0.0 2.2 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 KFM29187.1 - 2.4e-19 69.8 1.2 4e-19 69.1 0.0 1.9 2 0 0 2 2 2 1 Origin recognition complex winged helix C-terminal Mem_trans PF03547.18 KFM29188.1 - 1.2e-34 119.3 12.4 1.4e-17 63.2 2.4 2.0 2 0 0 2 2 2 2 Membrane transport protein Patatin PF01734.22 KFM29189.1 - 6.9e-13 49.2 3.3 1.2e-10 41.9 3.3 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase PTPLA PF04387.14 KFM29190.1 - 3.5e-36 124.4 1.6 5.5e-36 123.8 1.6 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Thioredoxin_6 PF13848.6 KFM29190.1 - 3.1e-22 79.4 0.0 5.6e-14 52.5 0.0 3.2 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin PF00085.20 KFM29190.1 - 1e-19 70.5 0.0 9.1e-10 38.5 0.0 2.8 2 1 0 2 2 2 2 Thioredoxin ERp29_N PF07912.13 KFM29190.1 - 0.021 15.0 0.1 19 5.4 0.0 3.3 3 1 0 3 3 3 0 ERp29, N-terminal domain Thioredoxin_2 PF13098.6 KFM29190.1 - 0.13 12.7 0.0 0.78 10.2 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like domain TMEM189_B_dmain PF10520.9 KFM29191.1 - 2.5e-58 197.0 0.0 3.1e-58 196.7 0.0 1.1 1 0 0 1 1 1 1 B domain of TMEM189, localisation domain FA_hydroxylase PF04116.13 KFM29191.1 - 0.00023 21.5 1.1 0.00031 21.1 0.8 1.4 1 1 0 1 1 1 1 Fatty acid hydroxylase superfamily DUF4131 PF13567.6 KFM29191.1 - 0.098 12.3 0.7 0.14 11.8 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) E2F_TDP PF02319.20 KFM29192.1 - 8.8e-17 60.9 0.0 1.6e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.19 KFM29192.1 - 0.019 14.8 0.1 2.3 8.1 0.0 2.3 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HSP90 PF00183.18 KFM29193.1 - 2.4e-186 620.7 0.0 3.2e-186 620.2 0.0 1.1 1 0 0 1 1 1 1 Hsp90 protein TPR_1 PF00515.28 KFM29193.1 - 2.9e-16 58.5 3.8 7.8e-06 25.5 0.8 4.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFM29193.1 - 8.3e-15 53.6 12.7 3.2e-06 26.8 1.3 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFM29193.1 - 1.8e-10 40.9 13.4 4.7e-07 30.0 0.5 4.3 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFM29193.1 - 2.2e-10 41.0 36.1 2.4e-09 37.7 6.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat HATPase_c PF02518.26 KFM29193.1 - 3.3e-10 40.4 0.0 6.6e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_11 PF13414.6 KFM29193.1 - 4.4e-10 39.1 3.2 0.00012 21.7 0.0 3.7 1 1 2 3 3 3 2 TPR repeat HATPase_c_3 PF13589.6 KFM29193.1 - 3.2e-08 33.5 0.0 6.3e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_9 PF13371.6 KFM29193.1 - 4.3e-08 33.2 16.9 0.0014 18.7 0.7 4.0 2 1 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFM29193.1 - 6.7e-08 32.0 3.9 0.031 14.3 0.6 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFM29193.1 - 7.8e-07 28.8 0.9 0.0016 18.5 0.1 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFM29193.1 - 1.8e-05 25.1 11.5 0.31 11.6 0.1 4.4 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFM29193.1 - 0.00056 20.1 9.1 0.06 13.7 0.1 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFM29193.1 - 0.00071 20.2 0.2 0.00071 20.2 0.2 6.8 5 1 2 7 7 6 2 Tetratricopeptide repeat BTAD PF03704.17 KFM29193.1 - 0.0019 18.7 0.1 0.0019 18.7 0.1 4.5 3 1 1 5 5 5 1 Bacterial transcriptional activator domain TPR_10 PF13374.6 KFM29193.1 - 0.0025 17.6 15.5 0.014 15.3 1.7 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFM29193.1 - 0.15 12.8 10.7 16 6.4 0.0 5.8 5 0 0 5 5 4 0 Tetratricopeptide repeat HSP70 PF00012.20 KFM29194.1 - 7.7e-258 856.6 8.3 8.8e-258 856.4 8.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFM29194.1 - 6.5e-18 64.6 0.9 1.9e-16 59.8 0.1 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 KFM29194.1 - 0.00053 20.4 4.8 0.8 10.2 0.3 3.6 3 2 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.18 KFM29194.1 - 0.0015 17.9 0.4 0.3 10.3 0.3 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase FGGY_C PF02782.16 KFM29194.1 - 0.02 14.6 0.1 0.46 10.2 0.0 2.5 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.11 KFM29194.1 - 0.081 12.1 0.0 0.21 10.8 0.0 1.7 2 0 0 2 2 2 0 StbA protein Nnf1 PF03980.14 KFM29194.1 - 1.7 9.0 5.5 0.33 11.4 1.0 2.1 2 0 0 2 2 2 0 Nnf1 Radial_spoke_3 PF06098.11 KFM29194.1 - 2.9 7.1 7.6 0.17 11.1 2.1 1.8 2 0 0 2 2 2 0 Radial spoke protein 3 Response_reg PF00072.24 KFM29195.1 - 0.0027 17.9 0.0 0.0042 17.2 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GUN4 PF05419.12 KFM29196.1 - 1.5e-46 157.9 0.3 1.8e-46 157.7 0.3 1.0 1 0 0 1 1 1 1 GUN4-like Med17 PF10156.9 KFM29197.1 - 0.19 10.4 0.0 11 4.6 0.0 2.0 1 1 1 2 2 2 0 Subunit 17 of Mediator complex IMPDH PF00478.25 KFM29198.1 - 3.5e-75 253.1 0.0 8e-49 166.5 0.0 2.0 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 KFM29198.1 - 1.5e-10 41.4 0.0 1e-05 25.8 0.0 2.6 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 KFM29198.1 - 2.5e-09 36.6 2.0 3.5e-08 32.9 0.6 2.3 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 KFM29198.1 - 1.5e-07 31.2 7.4 3.9e-05 23.2 1.6 2.8 3 0 0 3 3 3 2 Nitronate monooxygenase His_biosynth PF00977.21 KFM29198.1 - 0.0016 18.0 0.2 0.03 13.8 0.1 2.2 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 KFM29198.1 - 0.013 14.8 0.3 0.034 13.5 0.2 1.7 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG YpsA PF06908.11 KFM29198.1 - 0.019 14.9 0.0 0.031 14.3 0.0 1.2 1 0 0 1 1 1 0 YspA SLOG family eIF-1a PF01176.19 KFM29199.1 - 1.9e-22 78.8 0.2 3.1e-22 78.1 0.2 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Ribosomal_S5_C PF03719.15 KFM29200.1 - 1.2e-40 136.8 0.5 5.4e-19 67.4 0.1 2.4 2 0 0 2 2 2 2 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 KFM29200.1 - 1.9e-20 72.6 0.1 3.6e-20 71.7 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Aa_trans PF01490.18 KFM29202.1 - 1e-29 103.5 12.4 4.3e-22 78.4 2.0 2.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein SPRY PF00622.28 KFM29203.1 - 1.2e-21 77.0 0.1 1.8e-21 76.5 0.1 1.2 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.9 KFM29203.1 - 1.7e-12 47.4 0.0 2.5e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KFM29203.1 - 0.082 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 LisH Sin_N PF04801.13 KFM29204.1 - 3e-38 132.2 0.0 1.3e-37 130.1 0.0 1.8 2 0 0 2 2 2 1 Sin-like protein conserved region tRNA-synt_1 PF00133.22 KFM29205.1 - 9.1e-198 658.3 0.0 1e-196 654.8 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KFM29205.1 - 1.5e-36 125.6 0.0 3.5e-36 124.5 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KFM29205.1 - 8.6e-15 54.4 0.3 4.2e-08 32.4 0.0 4.5 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 KFM29205.1 - 4.4e-11 42.6 0.0 2.2e-07 30.6 0.0 2.6 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 KFM29205.1 - 0.00015 21.3 0.0 0.38 10.1 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Val_tRNA-synt_C PF10458.9 KFM29205.1 - 0.003 17.8 10.2 0.003 17.8 10.2 2.8 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1b PF00579.25 KFM29205.1 - 2.7 7.2 4.9 9.1 5.5 0.0 2.5 3 0 0 3 3 3 0 tRNA synthetases class I (W and Y) Ribosomal_L28 PF00830.19 KFM29206.1 - 8.7e-22 77.1 3.8 1.4e-21 76.4 3.8 1.3 1 0 0 1 1 1 1 Ribosomal L28 family DENN PF02141.21 KFM29207.1 - 4.7e-14 52.8 0.2 8.6e-14 51.9 0.2 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.19 KFM29207.1 - 6.6e-05 22.8 0.0 0.00014 21.7 0.0 1.5 1 0 0 1 1 1 1 dDENN domain AAA PF00004.29 KFM29208.1 - 2.4e-40 138.0 0.0 6.9e-40 136.5 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFM29208.1 - 4.6e-11 42.3 0.0 1.2e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KFM29208.1 - 3.5e-05 24.1 0.1 0.0025 18.1 0.0 2.5 2 1 1 3 3 2 1 AAA domain AAA_16 PF13191.6 KFM29208.1 - 9.7e-05 22.8 0.1 0.0012 19.3 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 KFM29208.1 - 0.00019 21.6 0.0 0.00036 20.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KFM29208.1 - 0.00036 20.6 0.1 0.0017 18.4 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KFM29208.1 - 0.003 17.7 0.0 0.0063 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KFM29208.1 - 0.0042 16.9 0.0 0.0087 15.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KFM29208.1 - 0.0099 16.1 0.0 0.019 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFM29208.1 - 0.011 16.3 0.0 0.072 13.6 0.0 2.3 3 0 0 3 3 2 0 AAA domain DUF815 PF05673.13 KFM29208.1 - 0.014 14.5 0.0 0.025 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 KFM29208.1 - 0.017 15.5 0.0 0.034 14.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 KFM29208.1 - 0.019 14.9 0.0 1.2 8.9 0.0 2.3 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 KFM29208.1 - 0.019 14.5 0.0 0.058 12.9 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region TIP49 PF06068.13 KFM29208.1 - 0.021 14.0 0.0 0.069 12.3 0.0 1.8 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_24 PF13479.6 KFM29208.1 - 0.039 13.7 0.2 0.2 11.3 0.0 2.1 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KFM29208.1 - 0.058 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 KFM29208.1 - 0.069 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI cobW PF02492.19 KFM29208.1 - 0.097 12.3 0.0 4.6 6.8 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PhoH PF02562.16 KFM29208.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein DNA_ligase_A_N PF04675.14 KFM29208.1 - 0.15 12.3 0.0 0.94 9.8 0.0 2.2 2 1 0 2 2 2 0 DNA ligase N terminus SF3b1 PF08920.10 KFM29210.1 - 1e-24 87.3 14.2 2.2e-23 83.0 14.2 3.3 1 1 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT PF02985.22 KFM29210.1 - 3e-09 36.3 6.7 34 5.1 0.0 10.1 11 0 0 11 11 11 0 HEAT repeat Cnd1 PF12717.7 KFM29210.1 - 3.9e-05 23.7 3.6 8 6.5 0.1 6.0 7 1 0 7 7 7 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KFM29210.1 - 6.8e-05 23.3 13.1 0.23 12.0 0.0 8.1 8 1 1 9 9 9 1 HEAT-like repeat DUF3730 PF12530.8 KFM29210.1 - 0.019 14.5 0.0 0.21 11.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3730) DUF1780 PF08682.10 KFM29210.1 - 0.24 11.1 1.8 2.3 7.9 0.1 3.2 4 1 1 5 5 5 0 Putative endonuclease, protein of unknown function (DUF1780) Phage_TAC_6 PF09550.10 KFM29210.1 - 3.3 8.2 5.7 0.52 10.8 0.3 2.5 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC AA_kinase PF00696.28 KFM29211.1 - 7.3e-27 94.5 0.4 8.6e-27 94.3 0.4 1.1 1 0 0 1 1 1 1 Amino acid kinase family IncD PF17628.2 KFM29211.1 - 0.66 9.7 3.2 0.93 9.3 1.3 2.0 2 0 0 2 2 2 0 Inclusion membrane protein D Sigma70_r4 PF04545.16 KFM29212.1 - 3.6e-11 42.4 0.0 1.5e-08 34.0 0.0 2.5 2 1 0 2 2 2 2 Sigma-70, region 4 Sigma70_r3 PF04539.16 KFM29212.1 - 8.2e-09 35.5 1.8 1.9e-08 34.3 1.3 1.8 1 1 1 2 2 2 1 Sigma-70 region 3 LexA_DNA_bind PF01726.16 KFM29212.1 - 0.0039 16.9 0.1 1.7 8.5 0.0 3.0 2 1 1 3 3 3 2 LexA DNA binding domain Oleosin PF01277.17 KFM29212.1 - 0.051 13.3 0.0 0.089 12.6 0.0 1.4 1 0 0 1 1 1 0 Oleosin PLU-1 PF08429.11 KFM29213.1 - 1.8e-36 126.0 0.0 5.6e-16 58.6 0.0 7.0 4 2 2 6 6 6 5 PLU-1-like protein PHD PF00628.29 KFM29213.1 - 1.2e-16 60.3 29.2 1.1e-10 41.2 8.3 3.1 3 0 0 3 3 3 2 PHD-finger zf-C5HC2 PF02928.16 KFM29213.1 - 2.6e-09 37.3 5.8 7e-09 35.9 5.8 1.8 1 0 0 1 1 1 1 C5HC2 zinc finger JmjC PF02373.22 KFM29213.1 - 2.6e-06 27.8 0.0 4.2e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD_4 PF16866.5 KFM29213.1 - 0.0082 16.2 1.4 0.0082 16.2 1.4 3.0 3 0 0 3 3 3 2 PHD-finger PHD_3 PF13922.6 KFM29213.1 - 0.034 14.5 0.2 0.034 14.5 0.2 3.2 3 0 0 3 3 3 0 PHD domain of transcriptional enhancer, Asx PHD_2 PF13831.6 KFM29213.1 - 0.035 13.7 10.0 0.073 12.6 3.4 2.9 2 0 0 2 2 2 0 PHD-finger zf-PHD-like PF15446.6 KFM29213.1 - 0.26 10.9 9.3 2 8.0 2.9 2.5 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Rubredoxin PF00301.20 KFM29213.1 - 0.95 9.5 11.4 0.13 12.3 1.9 3.2 3 0 0 3 3 3 0 Rubredoxin ARID PF01388.21 KFM29214.1 - 3.7e-13 49.9 0.0 6.1e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 KFM29214.1 - 0.0054 16.7 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 jmjN domain JmjC PF02373.22 KFM29214.1 - 0.047 14.1 0.0 0.074 13.5 0.0 1.3 1 0 0 1 1 1 0 JmjC domain, hydroxylase Nudix_hydro PF18290.1 KFM29215.1 - 3.7e-28 97.3 0.0 6.1e-28 96.6 0.0 1.4 1 0 0 1 1 1 1 Nudix hydrolase domain NUDIX PF00293.28 KFM29215.1 - 1.9e-17 63.5 0.1 3.1e-17 62.8 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain Actin PF00022.19 KFM29216.1 - 6.7e-44 150.1 0.0 2.5e-24 85.7 0.0 2.8 2 1 0 2 2 2 2 Actin Lactamase_B PF00753.27 KFM29217.1 - 6.4e-11 42.6 0.1 7.4e-11 42.4 0.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KFM29217.1 - 0.0041 16.7 0.1 0.0053 16.3 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 KFM29217.1 - 0.0048 16.4 0.0 0.0063 16.0 0.0 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KFM29217.1 - 0.066 13.1 0.0 0.083 12.8 0.0 1.2 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Bromodomain PF00439.25 KFM29218.1 - 1.5e-18 66.6 0.0 2.2e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Bromodomain VKOR PF07884.14 KFM29219.1 - 1.1e-20 74.0 6.8 1.1e-20 74.0 6.8 1.5 2 0 0 2 2 2 1 Vitamin K epoxide reductase family Tropomyosin PF00261.20 KFM29220.1 - 0.041 13.3 21.2 0.49 9.7 1.2 2.0 1 1 1 2 2 2 0 Tropomyosin CCDC144C PF14915.6 KFM29220.1 - 0.072 12.2 13.6 0.1 11.7 13.6 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Tropomyosin_1 PF12718.7 KFM29220.1 - 1.2 9.3 17.5 1.4 9.1 13.3 2.0 1 1 1 2 2 2 0 Tropomyosin like EamA PF00892.20 KFM29221.1 - 4.6e-43 146.7 21.9 1.8e-21 76.7 1.1 2.0 2 0 0 2 2 2 2 EamA-like transporter family NifU_N PF01592.16 KFM29222.1 - 3.2e-52 176.0 0.2 3.8e-52 175.8 0.2 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain DUF3659 PF12396.8 KFM29222.1 - 0.079 12.9 0.2 0.2 11.6 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) DUF455 PF04305.14 KFM29223.1 - 3.2e-79 266.0 0.0 7.2e-79 264.8 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF455) Nup192 PF11894.8 KFM29224.1 - 2.9e-07 28.1 0.2 9.8e-07 26.3 0.0 1.7 2 0 0 2 2 2 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 Nup188 PF10487.9 KFM29224.1 - 2.3e-05 22.6 0.0 3.9e-05 21.8 0.0 1.3 1 1 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 AIRC PF00731.20 KFM29226.1 - 4.1e-09 36.2 5.2 4.1e-09 36.2 5.2 1.6 1 1 0 1 1 1 1 AIR carboxylase ABC_tran PF00005.27 KFM29227.1 - 1.8e-45 154.8 0.1 4.1e-21 75.9 0.0 3.2 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 KFM29227.1 - 7.6e-17 62.1 0.0 0.002 18.0 0.0 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 KFM29227.1 - 1.9e-07 31.5 0.0 0.0045 17.4 0.0 3.7 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KFM29227.1 - 7.8e-07 29.5 0.0 0.03 14.6 0.0 2.9 3 0 0 3 3 2 2 AAA domain SMC_N PF02463.19 KFM29227.1 - 8.9e-07 28.6 0.1 0.61 9.5 0.0 4.3 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KFM29227.1 - 2.5e-06 27.1 0.3 0.052 13.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KFM29227.1 - 3.5e-06 27.5 0.5 0.082 13.3 0.1 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 KFM29227.1 - 1.5e-05 25.6 10.6 0.0045 17.5 0.0 3.6 4 0 0 4 4 3 2 AAA domain NACHT PF05729.12 KFM29227.1 - 2.1e-05 24.5 0.0 0.065 13.1 0.0 2.4 2 0 0 2 2 2 2 NACHT domain RsgA_GTPase PF03193.16 KFM29227.1 - 2.6e-05 24.2 0.0 0.077 12.9 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KFM29227.1 - 6.3e-05 23.3 0.0 0.16 12.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KFM29227.1 - 6.3e-05 23.0 0.0 0.15 12.1 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase ABC_tran_Xtn PF12848.7 KFM29227.1 - 6.6e-05 22.9 22.7 7e-05 22.8 10.7 2.9 3 0 0 3 3 2 2 ABC transporter cobW PF02492.19 KFM29227.1 - 0.00014 21.5 0.0 0.6 9.7 0.0 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 KFM29227.1 - 0.00031 21.1 0.0 0.35 11.3 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 KFM29227.1 - 0.0011 19.1 2.2 1.4 9.1 0.0 3.2 3 1 0 3 3 2 2 AAA domain AAA_18 PF13238.6 KFM29227.1 - 0.0014 19.2 0.2 2.2 8.8 0.0 3.4 4 0 0 4 4 2 1 AAA domain AAA_24 PF13479.6 KFM29227.1 - 0.0014 18.3 0.0 0.21 11.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.6 KFM29227.1 - 0.0015 17.3 1.2 2.1 6.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 KFM29227.1 - 0.0021 17.8 1.1 0.79 9.4 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KFM29227.1 - 0.005 16.9 0.0 2.6 8.1 0.0 2.9 3 0 0 3 3 2 1 AAA domain NB-ARC PF00931.22 KFM29227.1 - 0.0063 15.7 0.0 0.87 8.7 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain Dynamin_N PF00350.23 KFM29227.1 - 0.008 16.2 0.1 12 6.0 0.0 3.4 3 0 0 3 3 3 0 Dynamin family AAA_15 PF13175.6 KFM29227.1 - 0.0082 15.9 5.9 1.9 8.1 0.0 3.6 4 0 0 4 4 3 1 AAA ATPase domain NTPase_1 PF03266.15 KFM29227.1 - 0.0092 15.9 0.0 0.82 9.6 0.0 2.5 2 0 0 2 2 2 1 NTPase AAA_5 PF07728.14 KFM29227.1 - 0.015 15.3 0.1 2.6 8.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Cytidylate_kin PF02224.18 KFM29227.1 - 0.017 14.8 0.0 2.7 7.7 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase SRP54 PF00448.22 KFM29227.1 - 0.018 14.7 0.0 1 9.0 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain 5_3_exonuc_N PF02739.16 KFM29227.1 - 0.022 14.7 0.0 6.3 6.7 0.0 2.5 2 0 0 2 2 2 0 5'-3' exonuclease, N-terminal resolvase-like domain AAA_7 PF12775.7 KFM29227.1 - 0.023 14.2 0.1 3.2 7.2 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Rad17 PF03215.15 KFM29227.1 - 0.034 14.1 0.0 3.3 7.6 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain TsaE PF02367.17 KFM29227.1 - 0.034 14.1 0.2 3 7.8 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 KFM29227.1 - 0.038 13.5 0.0 2.5 7.6 0.0 3.1 3 0 0 3 3 2 0 AAA domain RuvB_N PF05496.12 KFM29227.1 - 0.048 13.4 0.4 2.4 7.9 0.1 2.5 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Roc PF08477.13 KFM29227.1 - 0.06 13.6 0.0 4.2 7.6 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATPase_2 PF01637.18 KFM29227.1 - 0.063 13.2 0.9 2.8 7.8 0.0 2.8 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea ATP-synt_ab PF00006.25 KFM29227.1 - 0.1 12.2 0.3 12 5.5 0.0 2.6 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF87 PF01935.17 KFM29227.1 - 0.24 11.5 1.6 30 4.6 0.0 2.9 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_27 PF13514.6 KFM29227.1 - 0.35 10.4 4.3 4.5 6.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain DUF3106 PF11304.8 KFM29227.1 - 0.4 11.2 6.5 0.06 13.8 1.6 2.1 2 0 0 2 2 1 0 Protein of unknown function (DUF3106) DUF3584 PF12128.8 KFM29227.1 - 0.94 6.9 12.6 0.14 9.7 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) ECM11 PF15463.6 KFM29227.1 - 1.4 9.5 9.7 0.13 12.9 0.8 3.0 4 0 0 4 4 2 0 Extracellular mutant protein 11 DUF3987 PF13148.6 KFM29227.1 - 8.2 5.3 0.0 8.2 5.3 0.0 3.2 4 0 0 4 4 3 0 Protein of unknown function (DUF3987) AOX PF01786.17 KFM29228.1 - 6.9e-25 87.9 0.6 9.3e-25 87.5 0.6 1.1 1 0 0 1 1 1 1 Alternative oxidase COQ7 PF03232.13 KFM29228.1 - 0.044 13.6 0.0 0.088 12.6 0.0 1.5 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 Ank_4 PF13637.6 KFM29229.1 - 8.4e-21 74.1 2.2 1.2e-13 51.2 1.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFM29229.1 - 3.6e-19 69.1 0.1 2.9e-18 66.2 0.2 1.9 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KFM29229.1 - 1.7e-15 56.6 7.5 6.2e-08 32.7 0.9 3.1 3 1 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KFM29229.1 - 2.2e-15 56.5 0.5 3.7e-08 33.5 0.2 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFM29229.1 - 1.1e-14 53.1 0.1 3.1e-05 24.0 0.1 3.6 4 0 0 4 4 4 2 Ankyrin repeat AAA_5 PF07728.14 KFM29230.1 - 1e-21 77.4 0.0 1.8e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_8 PF17868.1 KFM29230.1 - 3e-15 55.8 0.1 6.2e-15 54.8 0.1 1.6 1 0 0 1 1 1 1 AAA lid domain AAA_3 PF07726.11 KFM29230.1 - 0.00047 20.0 0.0 0.00082 19.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KFM29230.1 - 0.0012 18.2 0.0 0.0039 16.6 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA PF00004.29 KFM29230.1 - 0.022 15.2 0.0 0.07 13.6 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KFM29230.1 - 0.022 15.0 0.0 7.3 6.8 0.0 3.0 2 1 0 2 2 2 0 AAA domain MCM PF00493.23 KFM29230.1 - 0.14 11.2 0.0 1.1 8.4 0.0 1.9 1 1 0 2 2 2 0 MCM P-loop domain AAA_16 PF13191.6 KFM29230.1 - 2 8.7 10.2 0.061 13.7 0.4 3.1 3 1 0 3 3 3 0 AAA ATPase domain Pkinase PF00069.25 KFM29231.1 - 5e-63 212.9 0.0 6.4e-63 212.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain EF-hand_6 PF13405.6 KFM29231.1 - 1.9e-23 80.3 1.3 2.9e-05 23.6 0.0 6.8 7 0 0 7 7 7 4 EF-hand domain Pkinase_Tyr PF07714.17 KFM29231.1 - 2e-23 83.0 0.0 2.7e-23 82.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 KFM29231.1 - 1.9e-21 76.3 0.0 2.6e-07 31.0 0.0 4.7 4 1 0 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.32 KFM29231.1 - 1.4e-18 65.0 0.0 0.0019 17.6 0.0 6.9 8 0 0 8 8 8 4 EF hand EF-hand_8 PF13833.6 KFM29231.1 - 1.1e-12 47.6 5.1 3e-05 23.8 0.0 5.8 3 3 3 6 6 6 4 EF-hand domain pair EF-hand_5 PF13202.6 KFM29231.1 - 3.2e-08 32.7 5.1 0.0049 16.3 0.0 4.5 5 0 0 5 5 5 2 EF hand EF-hand_9 PF14658.6 KFM29231.1 - 3.6e-05 24.0 0.2 8.5 6.8 0.0 4.8 4 1 1 5 5 5 2 EF-hand domain DSBA PF01323.20 KFM29231.1 - 0.029 14.1 0.2 0.87 9.3 0.0 2.3 2 0 0 2 2 2 0 DSBA-like thioredoxin domain Caleosin PF05042.13 KFM29231.1 - 0.057 13.3 0.1 5.4 6.9 0.0 2.8 3 0 0 3 3 3 0 Caleosin related protein Sod_Fe_C PF02777.18 KFM29232.1 - 6.5e-32 109.7 0.3 2.9e-31 107.7 0.3 2.0 1 1 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KFM29232.1 - 1e-26 93.2 0.1 2e-26 92.3 0.1 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.18 KFM29233.1 - 6.6e-38 129.0 0.0 1.2e-37 128.2 0.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KFM29233.1 - 1.5e-29 102.2 0.1 2.6e-29 101.5 0.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain VPS13 PF16908.5 KFM29234.1 - 2.6e-38 132.2 0.0 3.1e-36 125.4 0.0 2.7 2 1 1 3 3 3 2 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 KFM29234.1 - 2.4e-29 101.8 0.0 4.3e-29 101.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 VPS13_mid_rpt PF16910.5 KFM29234.1 - 4.3e-24 85.2 0.0 4.2e-20 72.2 0.0 2.8 2 1 0 2 2 2 2 Repeating coiled region of VPS13 Vps62 PF06101.11 KFM29234.1 - 7.8e-15 54.2 0.0 6.5e-06 24.7 0.0 3.9 3 1 1 4 4 4 3 Vacuolar protein sorting-associated protein 62 ATG_C PF09333.11 KFM29234.1 - 1.2e-06 28.7 0.0 3.8e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Pex24p PF06398.11 KFM29234.1 - 5e-06 25.7 0.3 7.6e-06 25.2 0.3 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin VPS13_C PF16909.5 KFM29234.1 - 0.021 14.6 0.3 0.62 9.8 0.0 2.2 1 1 1 2 2 2 0 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 KFM29234.1 - 0.15 11.4 0.0 0.5 9.7 0.0 1.7 2 0 0 2 2 2 0 SHR-binding domain of vacuolar-sorting associated protein 13 GIDA PF01134.22 KFM29235.1 - 2.5e-104 349.5 0.2 2.6e-49 168.3 1.0 3.1 1 1 2 3 3 3 3 Glucose inhibited division protein A GIDA_assoc PF13932.6 KFM29235.1 - 9e-17 62.0 0.1 7.4e-13 49.2 0.0 2.2 1 1 1 2 2 2 2 GidA associated domain FAD_oxidored PF12831.7 KFM29235.1 - 2.2e-08 33.9 1.9 3.2e-08 33.3 1.9 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFM29235.1 - 2.9e-06 26.6 6.0 3.5e-06 26.4 1.5 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KFM29235.1 - 2.8e-05 23.5 0.4 4.5e-05 22.8 0.4 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFM29235.1 - 0.00033 21.2 0.1 0.0011 19.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KFM29235.1 - 0.0018 17.4 0.4 0.0037 16.4 0.4 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 KFM29235.1 - 0.0024 16.6 0.6 0.0044 15.8 0.6 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 KFM29235.1 - 0.0054 16.0 0.0 0.0079 15.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFM29235.1 - 0.011 15.9 1.1 0.037 14.2 0.6 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFM29235.1 - 0.012 15.2 1.8 0.014 15.0 0.4 2.0 2 1 1 3 3 3 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KFM29235.1 - 0.013 14.8 1.1 0.023 14.0 0.5 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 KFM29235.1 - 0.031 13.5 0.6 0.05 12.8 0.2 1.5 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 KFM29235.1 - 0.15 11.3 0.1 0.31 10.2 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 KFM29235.1 - 0.24 10.2 0.5 0.39 9.5 0.5 1.3 1 0 0 1 1 1 0 Tryptophan halogenase FKBP_C PF00254.28 KFM29236.1 - 3.7e-11 43.2 0.0 6.1e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF2381 PF09544.10 KFM29236.1 - 0.034 13.7 0.0 0.039 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2381) Usp PF00582.26 KFM29237.1 - 4.3e-14 53.2 0.6 9.1e-14 52.2 0.6 1.5 1 1 0 1 1 1 1 Universal stress protein family Toprim PF01751.22 KFM29237.1 - 0.03 14.5 0.0 0.035 14.3 0.0 1.2 1 0 0 1 1 1 0 Toprim domain Usp PF00582.26 KFM29238.1 - 7.2e-12 46.0 0.8 9.4e-12 45.6 0.8 1.4 1 1 0 1 1 1 1 Universal stress protein family NUMOD3 PF07460.11 KFM29239.1 - 6.6e-08 32.7 1.3 3.7e-07 30.2 0.4 2.5 2 0 0 2 2 2 1 NUMOD3 motif (2 copies) SesA PF17107.5 KFM29239.1 - 0.0003 21.0 3.9 0.0005 20.3 3.1 1.7 1 1 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Ppx-GppA PF02541.16 KFM29239.1 - 0.007 15.8 1.2 0.007 15.8 1.2 1.7 2 0 0 2 2 2 1 Ppx/GppA phosphatase family AMP-binding PF00501.28 KFM29240.1 - 2.2e-29 102.3 0.0 6.8e-29 100.7 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme PQQ_3 PF13570.6 KFM29240.1 - 0.00027 21.3 1.2 0.79 10.3 0.0 4.3 4 0 0 4 4 4 2 PQQ-like domain DUF4101 PF13355.6 KFM29241.1 - 4.6e-18 65.8 0.1 7.9e-18 65.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4101) Pectate_lyase_3 PF12708.7 KFM29242.1 - 3.4e-12 46.7 2.0 2.6e-06 27.4 0.2 2.3 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KFM29242.1 - 0.0075 15.9 0.1 0.018 14.8 0.1 1.6 1 0 0 1 1 1 1 N terminal extension of bacteriophage endosialidase PAP_fibrillin PF04755.12 KFM29243.1 - 3.8e-17 62.9 0.0 4.9e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 PAP_fibrillin NUC153 PF08159.12 KFM29244.1 - 1.3e-10 40.9 1.3 2.9e-10 39.8 1.3 1.7 1 0 0 1 1 1 1 NUC153 domain Cytochrom_D1 PF02239.16 KFM29244.1 - 0.034 12.7 0.0 0.055 12.0 0.0 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain Ribul_P_3_epim PF00834.19 KFM29245.1 - 4.4e-80 267.8 1.4 6e-79 264.0 1.4 2.0 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family His_biosynth PF00977.21 KFM29245.1 - 0.047 13.1 0.1 0.3 10.5 0.0 2.0 2 0 0 2 2 2 0 Histidine biosynthesis protein ThiG PF05690.14 KFM29245.1 - 0.055 12.8 0.1 0.11 11.8 0.1 1.5 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG SBF_like PF13593.6 KFM29246.1 - 3.1e-25 89.1 20.0 4.6e-21 75.4 14.4 2.0 1 1 1 2 2 2 2 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 KFM29246.1 - 2.1e-07 30.8 10.5 4e-07 29.9 10.5 1.6 1 0 0 1 1 1 1 Sodium Bile acid symporter family Fst_toxin PF13955.6 KFM29246.1 - 0.1 12.6 0.2 0.1 12.6 0.2 2.3 2 0 0 2 2 2 0 Toxin Fst, type I toxin-antitoxin system Aldo_ket_red PF00248.21 KFM29247.1 - 7.2e-106 353.7 0.0 9.6e-52 176.0 0.0 2.6 2 2 0 2 2 2 2 Aldo/keto reductase family SCAMP PF04144.13 KFM29248.1 - 7e-43 146.9 13.1 8.1e-43 146.7 13.1 1.0 1 0 0 1 1 1 1 SCAMP family DUF3552 PF12072.8 KFM29248.1 - 0.059 12.8 1.2 0.084 12.3 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) AP2 PF00847.20 KFM29249.1 - 2.8e-07 30.7 0.0 6e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 AP2 domain SecA_DEAD PF07517.14 KFM29251.1 - 6.5e-118 393.2 0.0 1e-117 392.6 0.0 1.3 1 0 0 1 1 1 1 SecA DEAD-like domain SecA_SW PF07516.13 KFM29251.1 - 2.8e-50 171.2 1.3 4.2e-50 170.6 0.3 1.8 2 0 0 2 2 2 1 SecA Wing and Scaffold domain SecA_PP_bind PF01043.20 KFM29251.1 - 1.1e-36 125.9 0.1 6.2e-35 120.2 0.0 2.8 2 0 0 2 2 2 1 SecA preprotein cross-linking domain DEAD PF00270.29 KFM29251.1 - 2.1e-06 27.6 0.0 5.9e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFM29251.1 - 0.0051 17.1 0.2 0.038 14.3 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain peroxidase PF00141.23 KFM29251.1 - 0.051 13.3 0.0 0.09 12.5 0.0 1.4 1 0 0 1 1 1 0 Peroxidase Pkinase_Tyr PF07714.17 KFM29252.1 - 2.2e-60 204.1 0.0 2.9e-60 203.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFM29252.1 - 9.8e-50 169.3 0.0 1.3e-49 169.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KFM29252.1 - 0.0016 18.4 0.0 0.0035 17.3 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KFM29252.1 - 0.0031 16.9 0.0 0.086 12.1 0.0 2.2 2 0 0 2 2 2 1 Kinase-like CBM_2 PF00553.19 KFM29252.1 - 0.0078 16.5 0.1 0.022 15.1 0.1 1.7 1 0 0 1 1 1 1 Cellulose binding domain Pkinase_fungal PF17667.1 KFM29252.1 - 0.011 14.5 0.0 0.016 14.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KFM29252.1 - 0.047 12.6 0.0 0.29 10.0 0.0 1.9 2 0 0 2 2 2 0 Haspin like kinase domain ABC1 PF03109.16 KFM29252.1 - 0.12 12.5 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 ABC1 family HSP70 PF00012.20 KFM29253.1 - 8.9e-29 100.1 0.5 5.4e-23 81.0 0.1 2.2 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 KFM29253.1 - 3.1e-06 26.3 0.6 3.1e-06 26.3 0.6 1.7 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 KFM29253.1 - 0.027 14.9 0.0 0.034 14.6 0.0 1.3 1 0 0 1 1 1 0 Cell division protein FtsA StbA PF06406.11 KFM29253.1 - 0.34 10.1 0.1 0.45 9.7 0.1 1.1 1 0 0 1 1 1 0 StbA protein zf-RanBP PF00641.18 KFM29254.1 - 4.7e-07 29.0 7.6 6.5e-07 28.6 7.6 1.2 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zf-ribbon_3 PF13248.6 KFM29254.1 - 0.16 11.4 4.0 1 8.9 0.5 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-RRN7 PF11781.8 KFM29254.1 - 2.9 7.7 7.4 1.3 8.8 0.9 2.3 1 1 1 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 RRM_1 PF00076.22 KFM29255.1 - 4.2e-10 39.3 0.0 2.9e-05 23.8 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFM29255.1 - 0.00035 20.6 0.0 0.00038 20.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif FAD_binding_3 PF01494.19 KFM29256.1 - 5.9e-61 206.6 0.0 8.9e-35 120.6 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KFM29256.1 - 0.0032 17.1 0.1 0.052 13.1 0.2 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KFM29256.1 - 0.069 12.4 0.1 0.12 11.6 0.1 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 KFM29256.1 - 0.09 12.0 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KFM29256.1 - 0.11 11.8 3.1 0.15 11.4 0.3 2.3 2 1 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFM29256.1 - 0.48 10.7 3.5 0.31 11.3 0.2 2.4 3 1 0 3 3 3 0 NAD(P)-binding Rossmann-like domain SAD_SRA PF02182.17 KFM29258.1 - 5.7e-48 162.6 0.1 1.2e-47 161.5 0.1 1.5 1 0 0 1 1 1 1 SAD/SRA domain zf-RING_UBOX PF13445.6 KFM29258.1 - 1.8e-13 50.3 24.0 2.1e-08 34.1 1.1 2.9 2 1 0 2 2 2 2 RING-type zinc-finger zf-C3HC4 PF00097.25 KFM29258.1 - 1.2e-11 44.3 35.2 2.9e-06 27.0 5.0 3.2 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFM29258.1 - 1.5e-10 40.8 31.0 3.9e-05 23.4 17.0 3.3 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFM29258.1 - 3.9e-09 36.2 38.1 3.9e-06 26.6 2.7 3.0 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFM29258.1 - 7.5e-09 35.4 32.8 1e-05 25.4 3.8 2.6 2 0 0 2 2 2 2 zinc-RING finger domain zf-RING_2 PF13639.6 KFM29258.1 - 5.3e-07 29.9 35.8 0.00092 19.5 19.5 3.1 2 1 0 2 2 2 2 Ring finger domain zf-C3HC4_4 PF15227.6 KFM29258.1 - 6e-07 29.5 34.4 1.7e-05 24.9 1.3 2.8 3 0 0 3 3 2 2 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KFM29258.1 - 2.2e-05 24.2 35.4 0.01 15.7 19.2 3.3 3 0 0 3 3 3 2 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KFM29258.1 - 0.00025 21.1 22.7 0.068 13.3 1.9 3.7 4 0 0 4 4 4 2 zinc RING finger of MSL2 U-box PF04564.15 KFM29258.1 - 0.095 12.9 0.0 13 6.1 0.0 2.6 2 0 0 2 2 2 0 U-box domain zf-RING_4 PF14570.6 KFM29258.1 - 0.097 12.5 25.9 0.039 13.7 13.9 3.7 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 KFM29258.1 - 1.3 8.9 16.8 2.2 8.2 7.0 2.6 2 1 0 2 2 2 0 zf-RING of BARD1-type protein Rad50_zn_hook PF04423.14 KFM29258.1 - 2.9 7.8 7.8 0.54 10.1 1.1 2.7 3 0 0 3 3 3 0 Rad50 zinc hook motif FoP_duplication PF13865.6 KFM29259.1 - 1.9e-13 50.8 1.4 2.5e-13 50.4 1.4 1.2 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 Exo_endo_phos PF03372.23 KFM29260.1 - 5.1e-11 42.5 0.2 6.2e-11 42.3 0.2 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF629 PF04780.12 KFM29261.1 - 4e-07 29.0 0.0 5.6e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF629) Trp_syntA PF00290.20 KFM29262.1 - 3.5e-88 294.8 0.2 4.1e-88 294.6 0.2 1.0 1 0 0 1 1 1 1 Tryptophan synthase alpha chain His_biosynth PF00977.21 KFM29262.1 - 1.3e-05 24.8 0.0 2.1e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein FMN_dh PF01070.18 KFM29262.1 - 0.0007 18.7 1.0 0.011 14.7 0.1 2.6 2 1 1 3 3 3 1 FMN-dependent dehydrogenase Hydrolase PF00702.26 KFM29262.1 - 0.0048 17.2 0.3 0.0096 16.2 0.3 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase ThiG PF05690.14 KFM29262.1 - 0.0054 16.1 0.3 0.013 14.9 0.1 1.6 1 1 0 1 1 1 1 Thiazole biosynthesis protein ThiG Pterin_bind PF00809.22 KFM29262.1 - 0.011 15.4 0.1 0.29 10.8 0.0 2.7 1 1 1 2 2 2 0 Pterin binding enzyme PcrB PF01884.17 KFM29262.1 - 0.042 13.3 0.6 0.46 9.9 0.1 2.3 2 1 0 2 2 2 0 PcrB family NanE PF04131.14 KFM29262.1 - 0.052 12.7 0.1 0.11 11.7 0.1 1.6 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Spore_YtrH PF14034.6 KFM29262.1 - 0.16 12.1 1.6 0.24 11.6 0.3 1.9 2 0 0 2 2 2 0 Sporulation protein YtrH Exotox-A_bind PF09101.10 KFM29263.1 - 0.062 12.6 0.0 0.062 12.6 0.0 1.0 1 0 0 1 1 1 0 Exotoxin A binding DCX PF03607.17 KFM29264.1 - 0.17 12.0 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Doublecortin Hexapep PF00132.24 KFM29265.1 - 4.7e-08 32.5 0.0 0.0099 15.6 0.0 4.5 4 1 2 6 6 6 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KFM29265.1 - 0.084 12.6 0.4 3.7 7.4 0.4 3.2 1 1 2 3 3 3 0 Hexapeptide repeat of succinyl-transferase PALP PF00291.25 KFM29266.1 - 2.6e-11 43.5 0.1 3e-11 43.3 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF3530 PF12048.8 KFM29266.1 - 0.0038 16.7 0.0 0.0047 16.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3530) PALP PF00291.25 KFM29268.1 - 3e-68 230.4 1.3 3.5e-68 230.2 1.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF3530 PF12048.8 KFM29268.1 - 0.023 14.1 0.0 0.036 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) PK PF00224.21 KFM29270.1 - 8.1e-109 363.7 0.2 1.3e-108 363.0 0.2 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KFM29270.1 - 2.4e-16 60.0 0.0 8e-16 58.3 0.0 1.9 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KFM29270.1 - 0.00022 20.4 0.1 0.001 18.3 0.0 2.0 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Pentapeptide_2 PF01469.18 KFM29270.1 - 0.0014 18.5 29.5 0.0023 17.8 29.5 1.4 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) CLP_protease PF00574.23 KFM29272.1 - 4.7e-47 160.2 0.0 7.1e-47 159.6 0.0 1.2 1 0 0 1 1 1 1 Clp protease PDZ_3 PF17815.1 KFM29273.1 - 6.9e-45 152.5 0.1 1.1e-44 151.8 0.1 1.3 1 0 0 1 1 1 1 PDZ domain Trypsin_2 PF13365.6 KFM29273.1 - 3e-23 83.4 1.7 5.6e-23 82.5 1.4 1.6 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.26 KFM29273.1 - 4.4e-15 56.1 0.0 6.3e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 KFM29273.1 - 1.1e-08 35.3 0.0 6.6e-06 26.4 0.0 2.6 2 0 0 2 2 2 2 PDZ domain Peptidase_S46 PF10459.9 KFM29273.1 - 0.00019 20.2 1.2 0.00041 19.2 0.7 1.7 1 1 1 2 2 2 1 Peptidase S46 PDZ_6 PF17820.1 KFM29273.1 - 0.0016 18.3 0.2 0.42 10.5 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 KFM29273.1 - 0.024 15.0 0.0 0.083 13.2 0.0 1.9 2 0 0 2 2 2 0 PDZ domain TatD_DNase PF01026.21 KFM29274.1 - 7.8e-49 166.3 0.0 9.8e-49 166.0 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Cyclin_N PF00134.23 KFM29275.1 - 1e-47 161.1 1.0 1.8e-47 160.3 1.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFM29275.1 - 4.4e-23 81.6 0.1 8.3e-23 80.7 0.1 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain tRNA-synt_1c PF00749.21 KFM29276.1 - 1.2e-92 310.2 1.8 1.5e-82 277.0 0.1 2.2 1 1 1 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.15 KFM29276.1 - 3.2e-39 134.5 0.1 5.2e-39 133.9 0.1 1.3 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.18 KFM29276.1 - 9.5e-39 133.0 0.0 2.7e-38 131.6 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 KFM29276.1 - 1.5e-06 29.0 1.0 8.7e-06 26.6 1.0 2.1 1 1 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 FliL PF03748.14 KFM29276.1 - 0.21 12.2 0.4 4.8 7.8 0.0 2.5 2 0 0 2 2 2 0 Flagellar basal body-associated protein FliL Steroid_dh PF02544.16 KFM29278.1 - 1.5e-29 102.9 0.5 1.5e-29 102.9 0.5 1.9 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.23 KFM29278.1 - 6.3e-05 22.6 0.0 0.00028 20.6 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_4 PF18036.1 KFM29278.1 - 0.12 12.5 0.0 6.2 7.0 0.0 2.3 1 1 0 1 1 1 0 Ubiquitin-like domain FERM_f0 PF16511.5 KFM29278.1 - 0.13 12.6 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 N-terminal or F0 domain of Talin-head FERM APG6_N PF17675.1 KFM29279.1 - 0.25 11.8 4.1 0.43 11.1 1.4 2.3 2 1 0 2 2 2 0 Apg6 coiled-coil region CENP-H PF05837.12 KFM29279.1 - 0.35 11.3 0.1 0.35 11.3 0.1 2.4 3 0 0 3 3 3 0 Centromere protein H (CENP-H) Pkinase PF00069.25 KFM29280.1 - 0.058 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain CHCH PF06747.13 KFM29281.1 - 1.3e-06 28.3 2.1 1.9e-06 27.8 2.1 1.2 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.9 KFM29281.1 - 0.0071 16.6 1.4 0.0095 16.2 1.4 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 DUF4603 PF15376.6 KFM29281.1 - 0.027 11.9 0.5 0.032 11.6 0.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) DUF5600 PF18150.1 KFM29283.1 - 2.1e-24 86.1 1.9 2.7e-12 47.2 0.3 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF5600) EHD_N PF16880.5 KFM29283.1 - 7e-14 51.4 0.1 1.4e-13 50.5 0.1 1.5 1 0 0 1 1 1 1 N-terminal EH-domain containing protein Dynamin_N PF00350.23 KFM29283.1 - 3.6e-13 49.9 0.0 1.3e-11 44.8 0.0 2.2 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KFM29283.1 - 4.6e-08 33.1 0.0 1e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_4 PF12763.7 KFM29283.1 - 1.9e-05 24.5 0.0 6e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 KFM29283.1 - 0.0006 20.2 0.0 0.03 14.8 0.0 2.5 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 KFM29283.1 - 0.0048 16.3 0.0 0.31 10.7 0.0 3.4 4 0 0 4 4 4 1 EF hand EF-hand_5 PF13202.6 KFM29283.1 - 0.0066 15.9 0.0 0.026 14.0 0.0 2.1 1 0 0 1 1 1 1 EF hand AIG1 PF04548.16 KFM29283.1 - 0.021 14.2 0.0 0.29 10.4 0.0 2.3 3 0 0 3 3 3 0 AIG1 family EF-hand_6 PF13405.6 KFM29283.1 - 0.022 14.7 0.2 2.1 8.5 0.0 3.8 5 0 0 5 5 5 0 EF-hand domain BDV_P10 PF06515.11 KFM29283.1 - 0.051 13.6 0.1 0.15 12.1 0.0 1.7 2 0 0 2 2 2 0 Borna disease virus P10 protein RRM_1 PF00076.22 KFM29284.1 - 4.6e-05 23.1 0.0 8.7e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 KFM29285.1 - 3.7e-40 135.2 30.6 4.8e-10 39.9 0.6 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFM29285.1 - 1.4e-19 70.2 4.8 4.1e-05 23.8 0.1 6.4 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFM29285.1 - 2.9e-08 33.1 1.3 0.0006 18.9 0.4 3.9 2 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KFM29285.1 - 5.7e-06 26.4 0.1 0.00012 22.0 0.1 2.7 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 KFM29285.1 - 0.0063 14.6 4.5 0.062 11.3 4.5 2.3 1 1 0 1 1 1 1 IKI3 family Coatomer_WDAD PF04053.14 KFM29285.1 - 0.027 13.5 0.0 1.7 7.6 0.0 2.6 1 1 2 3 3 3 0 Coatomer WD associated region AbrB-like PF14250.6 KFM29285.1 - 0.059 13.5 0.0 9.2 6.4 0.0 2.4 1 1 1 2 2 2 0 AbrB-like transcriptional regulator DPPIV_N PF00930.21 KFM29285.1 - 0.62 8.8 4.8 5.4 5.7 0.0 3.1 2 1 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region GHMP_kinases_N PF00288.26 KFM29286.1 - 2e-07 31.1 2.0 3.9e-07 30.2 0.8 2.2 2 0 0 2 2 2 1 GHMP kinases N terminal domain 2-oxoacid_dh PF00198.23 KFM29288.1 - 1.5e-65 220.9 0.0 8e-54 182.5 0.0 2.1 1 1 1 2 2 2 2 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KFM29288.1 - 2.1e-34 117.2 3.5 6.3e-18 64.4 0.2 2.5 2 0 0 2 2 2 2 Biotin-requiring enzyme E3_binding PF02817.17 KFM29288.1 - 1.7e-13 50.7 0.4 4.7e-13 49.3 0.4 1.9 1 0 0 1 1 1 1 e3 binding domain YL1 PF05764.13 KFM29288.1 - 0.037 14.1 0.0 0.085 13.0 0.0 1.6 1 1 1 2 2 2 0 YL1 nuclear protein SPOUT_MTase PF02590.17 KFM29290.1 - 3.4e-39 134.3 0.0 3.7e-39 134.2 0.0 1.0 1 0 0 1 1 1 1 Predicted SPOUT methyltransferase MINDY_DUB PF04424.13 KFM29292.1 - 6e-33 113.3 0.0 1.2e-32 112.4 0.0 1.5 1 0 0 1 1 1 1 MINDY deubiquitinase MMS19_N PF14500.6 KFM29294.1 - 1.4e-49 169.1 0.0 4.4e-49 167.4 0.0 1.8 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 KFM29294.1 - 3.4e-05 23.2 3.0 0.2 10.7 0.0 4.0 4 0 0 4 4 4 2 RNAPII transcription regulator C-terminal EH_Signature PF15611.6 KFM29294.1 - 0.46 9.8 2.1 0.63 9.4 0.1 2.0 1 1 0 2 2 2 0 EH_Signature domain adh_short PF00106.25 KFM29295.1 - 3.1e-40 137.7 0.1 4.8e-40 137.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFM29295.1 - 3.2e-25 89.1 0.3 4.9e-25 88.4 0.3 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFM29295.1 - 7.5e-08 32.5 0.1 1.7e-07 31.3 0.1 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KFM29295.1 - 0.0054 16.2 0.2 0.014 14.9 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Laminin_G_3 PF13385.6 KFM29296.1 - 1.2e-09 38.5 10.1 0.0002 21.5 2.5 5.2 2 2 1 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily fn2 PF00040.19 KFM29296.1 - 0.00028 21.1 7.4 0.12 12.7 0.1 3.3 3 0 0 3 3 3 2 Fibronectin type II domain Pentapeptide_2 PF01469.18 KFM29297.1 - 0.056 13.3 14.1 0.23 11.4 2.7 2.5 2 0 0 2 2 2 0 Pentapeptide repeats (8 copies) PfkB PF00294.24 KFM29298.1 - 3.5e-49 167.7 2.9 5.8e-49 167.0 2.7 1.4 1 1 1 2 2 2 2 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KFM29298.1 - 3.2e-11 43.1 0.5 5e-11 42.5 0.5 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Carb_kinase PF01256.17 KFM29298.1 - 0.00017 21.1 0.8 0.00023 20.7 0.8 1.2 1 0 0 1 1 1 1 Carbohydrate kinase bPH_2 PF03703.14 KFM29299.1 - 3.9e-10 39.8 0.0 7.7e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Bacterial PH domain zf_CCCH_4 PF18345.1 KFM29300.1 - 4.7e-17 61.4 28.8 5.9e-06 26.2 1.1 4.3 4 0 0 4 4 4 4 Zinc finger domain Torus PF16131.5 KFM29300.1 - 5.5e-14 52.8 14.5 0.00018 22.2 0.1 4.2 2 1 2 4 4 4 4 Torus domain zf-CCCH PF00642.24 KFM29300.1 - 1.1e-13 50.7 19.6 0.0013 18.6 1.6 4.3 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KFM29300.1 - 3e-12 46.0 23.9 0.0001 22.0 1.7 4.4 4 0 0 4 4 4 4 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KFM29300.1 - 0.0026 18.1 20.0 0.22 12.0 0.1 4.4 4 0 0 4 4 4 2 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KFM29300.1 - 0.0037 17.5 13.5 0.012 15.8 3.8 3.0 2 2 0 2 2 2 2 Zinc-finger containing family FSH1 PF03959.13 KFM29301.1 - 1.4e-12 47.7 0.0 1.7e-12 47.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) TPR_12 PF13424.6 KFM29302.1 - 6.3e-09 36.0 10.1 8.3e-09 35.6 3.9 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFM29302.1 - 7.4e-06 25.7 4.9 0.049 13.8 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFM29302.1 - 1.2e-05 24.9 1.7 0.015 15.1 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFM29302.1 - 0.00023 20.9 8.4 0.00082 19.2 0.1 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat zf-C3HC4_3 PF13920.6 KFM29302.1 - 0.00058 19.7 13.6 0.0015 18.3 13.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFM29302.1 - 0.0091 15.8 15.9 0.023 14.5 15.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_7 PF13176.6 KFM29302.1 - 0.052 13.6 8.0 0.86 9.8 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-C3HC4_4 PF15227.6 KFM29302.1 - 0.072 13.3 8.6 0.34 11.1 8.9 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KFM29302.1 - 0.12 12.3 15.5 0.31 11.0 15.5 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 KFM29302.1 - 0.42 10.5 15.9 1 9.3 15.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFM29302.1 - 3.2 8.2 15.9 8.5 6.8 15.9 1.8 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 KFM29302.1 - 3.7 7.6 10.0 1.6 8.8 6.2 2.3 1 1 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 KFM29302.1 - 8.9 6.3 17.4 1.6 8.7 12.0 2.6 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 APC_u14 PF16635.5 KFM29304.1 - 0.08 13.5 0.0 0.13 12.8 0.0 1.2 1 0 0 1 1 1 0 Unstructured region on APC between SAMP and APC_crr Snapin_Pallidin PF14712.6 KFM29305.1 - 0.026 15.0 0.2 0.029 14.8 0.2 1.0 1 0 0 1 1 1 0 Snapin/Pallidin SmpB PF01668.18 KFM29305.1 - 0.081 12.8 0.1 0.091 12.6 0.1 1.1 1 0 0 1 1 1 0 SmpB protein CHD5 PF04420.14 KFM29305.1 - 0.14 12.0 0.0 0.16 11.8 0.0 1.0 1 0 0 1 1 1 0 CHD5-like protein DHHC PF01529.20 KFM29306.1 - 1.3e-32 112.7 4.9 1.3e-32 112.7 4.9 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase RexB PF15968.5 KFM29306.1 - 1.5 9.3 4.7 0.25 11.8 0.9 1.6 2 0 0 2 2 2 0 Membrane-anchored ion channel, Abi component DUF4079 PF13301.6 KFM29307.1 - 0.11 12.7 0.0 0.11 12.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) Fumarate_red_D PF02313.17 KFM29307.1 - 0.19 11.9 0.0 0.26 11.4 0.0 1.2 1 0 0 1 1 1 0 Fumarate reductase subunit D Carboxyl_trans PF01039.22 KFM29308.1 - 1.4e-187 624.2 0.0 1.6e-187 624.0 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain CLP_protease PF00574.23 KFM29308.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Clp protease MTCP1 PF08991.10 KFM29309.1 - 3.7e-12 46.3 9.8 4.4e-12 46.0 9.8 1.1 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 KFM29309.1 - 0.0051 16.9 5.1 0.013 15.6 5.3 1.7 1 1 0 1 1 1 1 CHCH domain CBF PF03914.17 KFM29310.1 - 1.3e-25 90.4 0.5 1.5e-24 87.0 0.0 2.3 2 0 0 2 2 2 1 CBF/Mak21 family NOC3p PF07540.11 KFM29310.1 - 5.5e-22 78.0 1.9 7.4e-22 77.6 0.0 2.1 2 0 0 2 2 2 1 Nucleolar complex-associated protein BT1 PF03092.16 KFM29311.1 - 6.3e-88 295.3 15.2 4e-49 167.2 1.0 2.9 1 1 2 3 3 3 3 BT1 family PrmC_N PF17827.1 KFM29311.1 - 0.044 14.4 0.5 9.7 6.9 0.3 2.4 2 0 0 2 2 2 0 PrmC N-terminal domain DUF647 PF04884.14 KFM29313.1 - 2.1e-70 237.1 0.2 2.9e-70 236.6 0.2 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Methyltransf_16 PF10294.9 KFM29314.1 - 2.3e-19 69.8 0.0 3.7e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 KFM29314.1 - 3.2e-07 30.0 0.0 5.2e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KFM29314.1 - 5.2e-05 23.9 0.0 0.00019 22.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFM29314.1 - 0.0006 20.4 0.0 0.0047 17.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFM29314.1 - 0.0025 17.6 0.0 0.0041 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFM29314.1 - 0.0038 17.1 0.0 0.0049 16.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFM29314.1 - 0.0078 16.9 0.0 0.014 16.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFM29314.1 - 0.094 12.3 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Met_10 PF02475.16 KFM29314.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.4 2 0 0 2 2 2 0 Met-10+ like-protein Cellulase PF00150.18 KFM29315.1 - 9.1e-13 48.3 2.1 1.4e-12 47.6 2.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 KFM29315.1 - 0.11 11.8 0.1 3.7 6.8 0.1 2.3 2 1 0 2 2 2 0 Beta-galactosidase ShK PF01549.24 KFM29315.1 - 0.24 12.0 20.8 2.3 8.8 2.1 2.6 2 0 0 2 2 2 0 ShK domain-like DUF2451 PF10474.9 KFM29317.1 - 5.2e-37 127.9 0.0 3.6e-21 76.0 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function C-terminus (DUF2451) Prok-E2_C PF14459.6 KFM29317.1 - 0.4 10.8 3.2 0.49 10.5 0.1 2.4 3 0 0 3 3 3 0 Prokaryotic E2 family C Vps54_N PF10475.9 KFM29318.1 - 0.00043 19.7 0.0 0.00075 18.9 0.0 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Vps54_N PF10475.9 KFM29319.1 - 5.3e-10 39.1 0.0 6.5e-10 38.8 0.0 1.0 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Trimer_CC PF08954.11 KFM29320.1 - 0.15 11.6 0.5 0.39 10.3 0.1 1.8 2 0 0 2 2 2 0 Trimerisation motif Bromodomain PF00439.25 KFM29321.1 - 3.3e-15 55.9 0.0 9.2e-15 54.5 0.0 1.7 2 0 0 2 2 2 1 Bromodomain DUF2188 PF09954.9 KFM29321.1 - 2.1 8.5 5.1 6.4 7.0 4.2 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) Pkinase PF00069.25 KFM29322.1 - 2e-84 283.1 0.0 1e-47 162.8 0.0 3.2 2 1 1 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KFM29322.1 - 6.7e-39 133.7 0.0 1.9e-21 76.5 0.0 3.2 1 1 1 3 3 3 3 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFM29322.1 - 9.3e-08 31.2 0.4 0.0099 14.7 0.1 2.2 2 0 0 2 2 2 2 Fungal protein kinase Mad3_BUB1_I PF08311.12 KFM29322.1 - 5.6e-07 29.6 0.0 9.4e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 RIO1 PF01163.22 KFM29322.1 - 2e-06 27.5 0.1 0.026 14.1 0.0 2.4 2 0 0 2 2 2 2 RIO1 family Kdo PF06293.14 KFM29322.1 - 6.4e-06 25.7 0.1 0.025 13.9 0.1 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFM29322.1 - 0.00028 20.9 12.8 0.0088 16.0 0.1 4.5 4 1 1 5 5 5 2 Phosphotransferase enzyme family FTA2 PF13095.6 KFM29322.1 - 0.00057 19.6 0.0 0.26 10.9 0.0 3.0 3 0 0 3 3 3 1 Kinetochore Sim4 complex subunit FTA2 DUF3248 PF11609.8 KFM29322.1 - 0.058 13.3 0.0 0.2 11.6 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3248) Kinase-like PF14531.6 KFM29322.1 - 0.12 11.7 0.3 6.1 6.1 0.1 3.1 3 2 0 3 3 3 0 Kinase-like DUF4477 PF14780.6 KFM29323.1 - 1.7e-22 80.0 3.8 2.5e-22 79.5 3.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4477) FAP PF07174.11 KFM29324.1 - 0.0083 15.6 5.1 0.0089 15.5 5.1 1.0 1 0 0 1 1 1 1 Fibronectin-attachment protein (FAP) Caleosin PF05042.13 KFM29325.1 - 5e-55 186.0 0.0 5.9e-55 185.8 0.0 1.0 1 0 0 1 1 1 1 Caleosin related protein EF-hand_6 PF13405.6 KFM29325.1 - 0.032 14.2 0.0 0.09 12.8 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.32 KFM29325.1 - 0.089 12.4 0.0 0.25 11.0 0.0 1.8 2 0 0 2 2 2 0 EF hand ANAPC4_WD40 PF12894.7 KFM29326.1 - 1.4e-11 44.6 0.0 0.0056 17.0 0.0 4.3 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFM29326.1 - 1.8e-10 41.2 10.3 0.059 14.3 0.0 6.4 5 1 1 6 6 6 4 WD domain, G-beta repeat WD40_like PF17005.5 KFM29326.1 - 0.042 13.2 0.0 0.36 10.1 0.0 2.0 1 1 1 2 2 2 0 WD40-like domain Rubredoxin PF00301.20 KFM29327.1 - 3.3e-18 65.5 6.7 4.2e-18 65.1 6.7 1.2 1 0 0 1 1 1 1 Rubredoxin HypA PF01155.19 KFM29327.1 - 0.031 14.3 0.2 0.044 13.8 0.2 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_Tnp_IS1595 PF12760.7 KFM29327.1 - 0.036 14.0 0.2 0.65 10.0 0.0 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.10 KFM29327.1 - 0.041 13.6 1.9 0.48 10.2 0.1 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain TF_Zn_Ribbon PF08271.12 KFM29327.1 - 0.047 13.2 1.9 3.2 7.3 0.0 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding Elf1 PF05129.13 KFM29327.1 - 0.048 13.7 0.5 2.2 8.4 0.0 2.1 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-RanBP PF00641.18 KFM29327.1 - 0.079 12.3 0.5 0.079 12.3 0.5 1.9 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others DUF2072 PF09845.9 KFM29327.1 - 0.11 12.7 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Zn-ribbon containing protein TFIIS_C PF01096.18 KFM29327.1 - 0.12 12.3 2.5 0.7 9.8 0.2 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) DUF4731 PF15875.5 KFM29327.1 - 0.14 12.3 0.2 0.23 11.7 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4731) Zn-ribbon_8 PF09723.10 KFM29327.1 - 0.16 12.1 1.3 0.73 10.0 1.3 1.9 1 1 0 1 1 1 0 Zinc ribbon domain zf-C2H2_3 PF13878.6 KFM29327.1 - 0.17 11.7 1.4 3.3 7.6 0.2 2.2 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO PHD_4 PF16866.5 KFM29327.1 - 0.17 12.0 1.2 0.31 11.2 1.2 1.4 1 1 0 1 1 1 0 PHD-finger DUF1998 PF09369.10 KFM29328.1 - 3.6e-14 53.3 2.0 9.3e-14 52.0 2.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) DEAD PF00270.29 KFM29329.1 - 1e-21 77.5 0.0 1.6e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ubiquitin PF00240.23 KFM29329.1 - 1.4e-05 24.7 0.0 2.5e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family PrmC_N PF17827.1 KFM29329.1 - 0.037 14.6 0.2 23 5.7 0.0 3.4 3 0 0 3 3 3 0 PrmC N-terminal domain ResIII PF04851.15 KFM29329.1 - 0.061 13.3 0.0 0.093 12.7 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Tropomyosin PF00261.20 KFM29330.1 - 0.052 12.9 11.5 0.078 12.3 11.5 1.1 1 0 0 1 1 1 0 Tropomyosin CENP-F_leu_zip PF10473.9 KFM29330.1 - 0.056 13.5 8.9 0.8 9.7 0.1 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 KFM29330.1 - 0.18 10.6 7.5 0.25 10.2 7.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein FeoB_N PF02421.18 KFM29330.1 - 0.22 11.1 0.4 0.31 10.6 0.4 1.1 1 0 0 1 1 1 0 Ferrous iron transport protein B DUF1664 PF07889.12 KFM29330.1 - 0.34 11.0 1.3 0.63 10.1 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2357 PF09823.9 KFM29330.1 - 0.69 9.1 6.0 0.22 10.7 3.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2357) GBP_C PF02841.14 KFM29330.1 - 1.1 8.6 7.9 1.6 8.0 7.9 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain HHV-5_US34A PF17087.5 KFM29330.1 - 1.3 9.2 3.7 16 5.8 0.2 2.9 3 0 0 3 3 3 0 Herpesvirus US34A protein family Csm1_N PF18504.1 KFM29330.1 - 4.8 7.6 7.9 11 6.5 3.7 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain NTP_transferase PF00483.23 KFM29331.1 - 1.2e-12 48.0 0.0 7.1e-12 45.4 0.0 1.9 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KFM29331.1 - 3.3e-12 47.0 5.6 5.3e-12 46.4 5.6 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 KFM29331.1 - 3.2e-09 36.2 7.4 0.00024 20.7 1.6 3.3 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KFM29331.1 - 0.00046 19.9 5.3 0.14 11.9 0.6 2.9 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 KFM29331.1 - 0.0022 17.0 0.2 0.27 10.1 0.1 2.1 1 1 1 2 2 2 2 L-fucokinase DUF4954 PF16314.5 KFM29331.1 - 0.059 11.5 0.6 0.11 10.6 0.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4954) Bactofilin PF04519.13 KFM29331.1 - 0.14 12.5 0.7 0.65 10.3 0.2 1.9 1 1 1 2 2 2 0 Polymer-forming cytoskeletal B56 PF01603.20 KFM29332.1 - 2e-254 844.0 0.0 1.2e-173 577.9 0.0 2.0 1 1 1 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) TetR_C_16 PF17920.1 KFM29332.1 - 0.00049 20.3 0.1 2.9 8.2 0.0 3.2 3 0 0 3 3 3 2 Tetracyclin repressor-like, C-terminal domain EntA_Immun PF08951.10 KFM29332.1 - 0.042 14.2 0.0 18 5.8 0.0 2.5 2 0 0 2 2 2 0 Enterocin A Immunity Toprim PF01751.22 KFM29332.1 - 0.078 13.2 0.0 23 5.3 0.0 2.4 2 0 0 2 2 2 0 Toprim domain RRM_1 PF00076.22 KFM29333.1 - 1.4e-09 37.6 0.0 2.1e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 KFM29334.1 - 2.7e-08 33.5 0.0 2.9e-08 33.4 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_transf_54 PF04666.13 KFM29335.1 - 4.8e-09 35.5 0.0 1.1e-08 34.4 0.0 1.5 2 0 0 2 2 2 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region GTP_EFTU PF00009.27 KFM29336.1 - 4.2e-67 225.4 0.0 6.7e-67 224.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KFM29336.1 - 2.6e-45 153.1 0.1 4.9e-45 152.2 0.1 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 KFM29336.1 - 2.8e-31 107.4 0.0 5.1e-31 106.6 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KFM29336.1 - 8.1e-28 96.3 0.1 2.1e-27 95.0 0.1 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KFM29336.1 - 1.3e-12 47.9 0.1 4.5e-12 46.2 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KFM29336.1 - 1.4e-06 28.1 0.0 3.3e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 KFM29336.1 - 0.0004 20.4 0.0 0.00091 19.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KFM29336.1 - 0.0097 15.2 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 AIG1 family zf-HC2 PF13490.6 KFM29336.1 - 0.074 13.3 0.4 0.16 12.2 0.4 1.5 1 0 0 1 1 1 0 Putative zinc-finger LSM PF01423.22 KFM29338.1 - 2.9e-19 68.5 0.2 3.6e-19 68.2 0.2 1.1 1 0 0 1 1 1 1 LSM domain ADH_zinc_N_2 PF13602.6 KFM29340.1 - 1.9e-25 90.5 0.1 5.4e-25 89.0 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KFM29340.1 - 4.4e-14 52.6 0.0 8.1e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFM29340.1 - 2e-07 30.9 0.2 7.6e-06 25.8 0.1 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KFM29340.1 - 0.035 14.0 0.1 0.07 13.0 0.1 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KFM29341.1 - 7.4e-27 95.0 0.1 1.4e-26 94.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KFM29341.1 - 4.4e-13 49.3 0.0 9.2e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFM29341.1 - 0.037 13.9 0.0 1.7 8.6 0.0 2.4 1 1 1 2 2 2 0 Alcohol dehydrogenase GroES-like domain Mito_carr PF00153.27 KFM29342.1 - 6.2e-57 189.5 1.8 9.1e-20 70.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein ICL PF00463.21 KFM29343.1 - 2.6e-100 336.4 0.8 9.1e-52 176.2 0.0 2.2 1 1 1 2 2 2 2 Isocitrate lyase family PEP_mutase PF13714.6 KFM29343.1 - 1.2e-16 61.0 0.0 2.1e-16 60.1 0.0 1.4 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase LMWPc PF01451.21 KFM29344.1 - 6e-15 55.9 0.0 1.6e-12 48.0 0.1 2.1 2 0 0 2 2 2 2 Low molecular weight phosphotyrosine protein phosphatase Phi_1 PF04674.12 KFM29345.1 - 0.15 11.4 0.2 0.14 11.4 0.2 1.0 1 0 0 1 1 1 0 Phosphate-induced protein 1 conserved region GHMP_kinases_N PF00288.26 KFM29346.1 - 3.7e-05 23.9 0.7 3.7e-05 23.9 0.7 2.7 3 0 0 3 3 3 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KFM29346.1 - 0.00072 19.9 0.1 0.0017 18.6 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal Glyco_transf_92 PF01697.27 KFM29347.1 - 2.2e-14 53.7 0.0 2.9e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 KFM29347.1 - 2e-10 41.0 0.4 6.9e-10 39.3 0.0 2.0 2 1 1 3 3 3 1 Glycosyl transferase family 2 RLL PF10036.9 KFM29348.1 - 2e-38 132.7 0.0 2.7e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 RNA transcription, translation and transport factor protein VCPO_N PF17897.1 KFM29348.1 - 0.034 13.9 0.1 0.43 10.3 0.0 2.2 2 0 0 2 2 2 0 Vanadium chloroperoxidase N-terminal domain HIRAN PF08797.11 KFM29349.1 - 5.4e-07 29.5 0.0 1.1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain OCRE PF17780.1 KFM29350.1 - 2.1e-17 62.9 2.5 3.7e-17 62.1 2.5 1.4 1 0 0 1 1 1 1 OCRE domain RRM_1 PF00076.22 KFM29350.1 - 1.2e-05 25.1 0.0 2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.18 KFM29350.1 - 4.7e-05 22.6 0.9 8e-05 21.9 0.9 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Cob_adeno_trans PF01923.18 KFM29351.1 - 1.6e-56 191.0 0.0 1.8e-56 190.8 0.0 1.0 1 0 0 1 1 1 1 Cobalamin adenosyltransferase Auto_anti-p27 PF06677.12 KFM29352.1 - 1.7e-22 79.3 9.7 6.1e-14 51.9 0.5 2.3 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DZR PF12773.7 KFM29352.1 - 0.001 19.0 8.3 0.15 12.1 2.0 2.3 2 0 0 2 2 2 2 Double zinc ribbon DUF2318 PF10080.9 KFM29352.1 - 0.048 13.8 0.9 1.8 8.7 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) RPA_interact_C PF14768.6 KFM29352.1 - 0.054 14.1 0.2 0.054 14.1 0.2 2.2 2 1 0 2 2 2 0 Replication protein A interacting C-terminal DUF2616 PF11077.8 KFM29352.1 - 0.67 9.6 2.2 1 9.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2616) GFA PF04828.14 KFM29352.1 - 0.89 9.9 5.0 6.9 7.1 0.3 2.9 2 1 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme C1_1 PF00130.22 KFM29352.1 - 1.1 9.2 4.1 14 5.7 0.4 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2HC5 PF06221.13 KFM29352.1 - 1.2 9.2 6.6 9.5 6.3 0.3 3.0 2 2 0 2 2 2 0 Putative zinc finger motif, C2HC5-type OrfB_Zn_ribbon PF07282.11 KFM29352.1 - 1.4 8.9 8.3 1.5 8.8 0.9 2.3 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Prok-RING_1 PF14446.6 KFM29352.1 - 1.9 8.5 7.7 4.8 7.2 0.4 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Nop25 PF09805.9 KFM29353.1 - 1e-14 55.2 10.5 1.9e-14 54.3 10.5 1.6 1 1 0 1 1 1 1 Nucleolar protein 12 (25kDa) Slu7 PF11708.8 KFM29353.1 - 0.011 15.4 0.6 0.015 15.1 0.6 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor Cgr1 PF03879.14 KFM29353.1 - 0.048 14.0 10.6 0.13 12.7 10.6 1.7 1 1 0 1 1 1 0 Cgr1 family Glyco_hydro_28 PF00295.17 KFM29354.1 - 1.1e-15 57.5 0.0 1.6e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 KFM29354.1 - 0.0084 16.0 0.0 0.11 12.4 0.0 2.1 1 1 0 1 1 1 1 Right handed beta helix region Malate_synthase PF01274.22 KFM29355.1 - 1.4e-207 690.2 0.0 1.5e-207 690.0 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Chlorophyllase2 PF12740.7 KFM29358.1 - 1.1e-13 50.7 0.0 1.7e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KFM29358.1 - 1.7e-10 40.4 0.1 2.7e-10 39.8 0.1 1.2 1 0 0 1 1 1 1 Chlorophyllase NT-C2 PF10358.9 KFM29358.1 - 5.2e-09 36.0 0.0 8e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Abhydrolase_1 PF00561.20 KFM29358.1 - 0.015 14.9 0.1 0.036 13.7 0.1 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFM29358.1 - 0.016 14.5 0.2 0.14 11.4 0.2 2.1 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Prefoldin_2 PF01920.20 KFM29358.1 - 1.5 8.8 3.7 0.7 9.9 0.1 2.3 3 0 0 3 3 3 0 Prefoldin subunit DivIC PF04977.15 KFM29358.1 - 5.7 6.8 6.7 3.9 7.3 0.0 3.3 3 1 1 4 4 4 0 Septum formation initiator S-methyl_trans PF02574.16 KFM29359.1 - 7.2e-47 160.4 0.0 3.7e-46 158.1 0.0 1.8 1 1 0 1 1 1 1 Homocysteine S-methyltransferase Pentapeptide_2 PF01469.18 KFM29364.1 - 0.00027 20.8 15.8 0.0004 20.2 15.8 1.2 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) UCR_14kD PF02271.16 KFM29364.1 - 0.081 12.9 0.0 0.1 12.6 0.0 1.1 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Chlorophyta/Auxenochlorella_protothecoides-ASM73321v1/GCA_000733215.1_ASM73321v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Chlorophyta/Auxenochlorella_protothecoides-ASM73321v1/GCA_000733215.1_ASM73321v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Chlorophyta/Auxenochlorella_protothecoides-ASM73321v1/GCA_000733215.1_ASM73321v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Chlorophyta/Auxenochlorella_protothecoides-ASM73321v1/GCA_000733215.1_ASM73321v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 05:22:05 2019 # [ok]