# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- ATP-synt_I PF03899.15 AIM19640.1 - 9.6e-19 67.6 10.0 1.3e-18 67.2 10.0 1.2 1 0 0 1 1 1 1 ATP synthase I chain ATP-synt_A PF00119.20 AIM19641.1 - 2.4e-56 191.0 20.0 2.9e-56 190.8 20.0 1.0 1 0 0 1 1 1 1 ATP synthase A chain CHD5 PF04420.14 AIM19641.1 - 0.18 11.7 7.2 0.2 11.5 2.1 2.4 2 0 0 2 2 2 0 CHD5-like protein DUF3333 PF11812.8 AIM19641.1 - 0.3 11.3 4.5 3.9 7.7 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3333) ATP-synt_C PF00137.21 AIM19642.1 - 1.2e-09 38.3 10.7 1.6e-09 37.9 10.6 1.3 1 1 0 1 1 1 1 ATP synthase subunit C HlyIII PF03006.20 AIM19642.1 - 0.029 14.1 0.4 0.038 13.7 0.4 1.1 1 0 0 1 1 1 0 Haemolysin-III related ATP-synt_B PF00430.18 AIM19643.1 - 7.8e-39 132.8 21.4 9.3e-39 132.5 21.4 1.1 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) ESM4 PF15952.5 AIM19643.1 - 0.0019 18.7 2.4 0.0027 18.2 2.4 1.2 1 0 0 1 1 1 1 Enhancer of split M4 family FNIP_C PF14638.6 AIM19643.1 - 0.0075 15.9 0.2 0.012 15.3 0.1 1.4 2 0 0 2 2 2 1 Folliculin-interacting protein C-terminus Mt_ATP-synt_B PF05405.14 AIM19643.1 - 0.0085 15.7 6.8 0.023 14.3 6.8 1.7 1 1 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) V-ATPase_G_2 PF16999.5 AIM19643.1 - 0.047 14.1 30.1 0.028 14.8 28.1 1.6 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit PhdYeFM_antitox PF02604.19 AIM19643.1 - 0.055 13.3 8.3 0.048 13.5 6.6 1.8 1 1 1 2 2 2 0 Antitoxin Phd_YefM, type II toxin-antitoxin system CRISPR_Cse1 PF09481.10 AIM19643.1 - 0.06 12.4 7.1 0.07 12.2 7.1 1.0 1 0 0 1 1 1 0 CRISPR-associated protein Cse1 (CRISPR_cse1) V-ATPase_G PF03179.15 AIM19643.1 - 0.39 11.3 27.2 0.41 11.2 23.4 2.5 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit DivIVA PF05103.13 AIM19643.1 - 1.1 9.3 25.6 3.7 7.6 24.0 2.2 1 1 1 2 2 2 0 DivIVA protein DUF819 PF05684.12 AIM19643.1 - 2 7.4 5.2 1.3 8.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF819) RNA_pol_Rpb2_45 PF10385.9 AIM19643.1 - 5.9 7.2 12.3 0.39 11.0 2.4 2.8 2 2 1 3 3 3 0 RNA polymerase beta subunit external 1 domain OSCP PF00213.18 AIM19644.1 - 2.6e-23 83.0 0.8 2.8e-23 82.9 0.8 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit ATP-synt_ab PF00006.25 AIM19645.1 - 2.5e-73 246.3 0.1 4.3e-73 245.5 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 AIM19645.1 - 4.1e-46 156.4 2.6 7.3e-46 155.6 2.3 1.5 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 AIM19645.1 - 8.5e-14 51.8 0.3 2.1e-13 50.6 0.3 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATPase PF06745.13 AIM19645.1 - 9.4e-05 21.9 0.1 0.00017 21.0 0.1 1.4 1 0 0 1 1 1 1 KaiC HAS-barrel PF09378.10 AIM19645.1 - 0.0027 17.8 0.4 0.011 15.8 0.1 2.2 2 1 0 2 2 2 1 HAS barrel domain ATPase_2 PF01637.18 AIM19645.1 - 0.048 13.6 0.0 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Viral_cys_rich PF08008.12 AIM19645.1 - 0.17 12.0 0.0 6 7.0 0.0 2.8 2 1 1 3 3 3 0 Viral cysteine rich ATP-synt PF00231.19 AIM19646.1 - 4.9e-97 325.0 0.0 5.4e-97 324.9 0.0 1.0 1 0 0 1 1 1 1 ATP synthase ATP-synt_ab PF00006.25 AIM19647.1 - 1.8e-62 210.8 0.0 2.4e-62 210.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 AIM19647.1 - 3e-20 72.5 2.2 6.2e-20 71.5 2.2 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain T3SS_ATPase_C PF18269.1 AIM19647.1 - 0.018 14.9 0.4 0.12 12.2 0.4 2.3 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain ATP-synt_DE_N PF02823.16 AIM19648.1 - 1.4e-30 105.0 0.2 2.1e-30 104.5 0.2 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain ATP-synt_DE PF00401.20 AIM19648.1 - 2.5e-13 50.0 6.1 3.9e-13 49.4 6.1 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Hexapep PF00132.24 AIM19649.1 - 4.7e-29 99.0 10.8 6.8e-07 28.8 2.3 5.3 2 1 3 5 5 5 5 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 AIM19649.1 - 8e-22 78.3 0.7 1.3e-21 77.7 0.7 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 AIM19649.1 - 3.3e-12 46.5 0.0 4.6e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.6 AIM19649.1 - 5.2e-12 45.3 15.0 9.3e-05 22.1 0.1 5.5 3 1 2 5 5 5 4 Hexapeptide repeat of succinyl-transferase IspD PF01128.19 AIM19649.1 - 5.3e-07 29.6 0.2 1.5e-06 28.1 0.2 1.8 1 1 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP_transf_3 PF02348.19 AIM19649.1 - 0.00026 21.0 0.0 0.0069 16.3 0.0 2.1 2 0 0 2 2 2 1 Cytidylyltransferase Fucokinase PF07959.12 AIM19649.1 - 0.0097 14.9 0.1 0.18 10.7 0.1 2.6 2 1 1 3 3 3 1 L-fucokinase CofC PF01983.16 AIM19649.1 - 0.013 14.7 0.0 0.025 13.8 0.0 1.4 1 0 0 1 1 1 0 Guanylyl transferase CofC like DUF4954 PF16314.5 AIM19649.1 - 0.016 13.4 0.4 0.098 10.8 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4954) SIS PF01380.22 AIM19650.1 - 2e-64 215.3 0.3 1.6e-32 112.1 0.2 2.2 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 AIM19650.1 - 1.3e-20 73.9 0.1 2.4e-20 73.1 0.1 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 AIM19650.1 - 4e-15 55.8 0.0 7.5e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 AIM19650.1 - 6.4e-05 22.0 0.1 0.00079 18.4 0.1 2.3 2 0 0 2 2 2 1 Glutamine amidotransferases class-II PBP_like_2 PF12849.7 AIM19651.1 - 1.5e-60 205.3 8.2 2e-60 204.9 8.2 1.1 1 0 0 1 1 1 1 PBP superfamily domain PBP_like PF12727.7 AIM19651.1 - 3.4e-11 42.6 0.0 8.8e-11 41.3 0.0 1.8 1 1 0 1 1 1 1 PBP superfamily domain BPD_transp_1 PF00528.22 AIM19652.1 - 6.6e-19 68.4 16.6 6.6e-19 68.4 16.6 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 AIM19653.1 - 1.2e-29 103.4 16.7 1.2e-29 103.4 16.7 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 AIM19654.1 - 3.4e-34 118.3 0.0 4.5e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIM19654.1 - 6.8e-10 39.2 0.0 0.00032 20.6 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIM19654.1 - 5.8e-07 29.2 0.0 7.2e-06 25.6 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 AIM19654.1 - 2.5e-05 24.2 0.0 2.6e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AIM19654.1 - 5.4e-05 23.5 0.0 0.00015 22.0 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_29 PF13555.6 AIM19654.1 - 6.4e-05 22.6 0.0 0.00014 21.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AIM19654.1 - 8.9e-05 22.5 0.0 0.00021 21.3 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 AIM19654.1 - 0.00018 21.9 0.0 0.00036 21.0 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 AIM19654.1 - 0.00025 21.6 0.2 0.00037 21.1 0.2 1.4 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 AIM19654.1 - 0.00044 20.2 0.0 0.00075 19.5 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 AIM19654.1 - 0.0077 16.0 0.0 0.17 11.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 AIM19654.1 - 0.044 13.9 0.1 0.099 12.8 0.1 1.6 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 AIM19654.1 - 0.052 12.7 0.0 0.052 12.7 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit TniB PF05621.11 AIM19654.1 - 0.054 12.9 0.0 0.19 11.1 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein AAA_25 PF13481.6 AIM19654.1 - 0.074 12.6 0.0 0.26 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 AIM19654.1 - 0.075 12.8 0.0 0.22 11.2 0.0 1.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_14 PF13173.6 AIM19654.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 AIM19654.1 - 0.12 12.6 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 AIM19654.1 - 0.13 12.3 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 AIM19654.1 - 0.13 11.9 0.1 0.32 10.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.15 AIM19654.1 - 0.13 11.0 0.0 0.63 8.8 0.0 1.8 2 0 0 2 2 2 0 Adenovirus IVa2 protein IstB_IS21 PF01695.17 AIM19654.1 - 0.15 11.8 0.1 4.1 7.1 0.0 2.7 3 0 0 3 3 3 0 IstB-like ATP binding protein ATPase_2 PF01637.18 AIM19654.1 - 0.17 11.8 0.0 0.56 10.1 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea PhoU PF01895.19 AIM19655.1 - 6.3e-40 135.5 7.9 7e-22 77.7 1.2 2.1 2 0 0 2 2 2 2 PhoU domain CCDC154 PF15450.6 AIM19655.1 - 0.015 13.9 0.5 0.022 13.3 0.5 1.2 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 154 HATPase_c_2 PF13581.6 AIM19655.1 - 0.11 12.5 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain SBP_bac_3 PF00497.20 AIM19656.1 - 5.6e-58 196.0 0.2 6.6e-58 195.8 0.2 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 AIM19656.1 - 5.1e-08 33.1 0.0 3.8e-06 27.1 0.0 2.9 2 1 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site BPD_transp_1 PF00528.22 AIM19657.1 - 1.2e-14 54.5 9.7 1.2e-14 54.5 9.7 1.4 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 AIM19658.1 - 4.5e-21 75.4 20.5 7.6e-21 74.7 20.5 1.3 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component DUF2613 PF11021.8 AIM19658.1 - 2.5 8.3 10.5 2 8.6 7.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2613) HAD_2 PF13419.6 AIM19659.1 - 2.2e-23 83.3 0.0 2.5e-23 83.1 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AIM19659.1 - 2.4e-11 44.3 0.0 1.7e-10 41.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AIM19659.1 - 0.0011 19.4 0.0 0.0015 19.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.18 AIM19659.1 - 0.0015 18.3 0.0 0.78 9.5 0.0 2.2 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase Hydrolase_6 PF13344.6 AIM19659.1 - 0.15 12.2 0.1 0.83 9.8 0.1 2.3 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AIM19659.1 - 0.17 12.0 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like NUDIX PF00293.28 AIM19660.1 - 1.4e-12 47.8 0.0 1.7e-12 47.5 0.0 1.0 1 0 0 1 1 1 1 NUDIX domain Xan_ur_permease PF00860.20 AIM19661.1 - 5.7e-41 140.5 50.8 5.7e-41 140.5 50.8 1.6 1 1 1 2 2 2 1 Permease family Hydrolase_4 PF12146.8 AIM19662.1 - 0.015 14.6 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 FMN_red PF03358.15 AIM19663.1 - 9.9e-40 135.8 0.0 1.3e-39 135.5 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 AIM19663.1 - 1.3e-08 34.8 0.0 1.6e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold ACPS PF01648.20 AIM19664.1 - 9.4e-05 22.5 0.0 0.00014 21.9 0.0 1.3 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily K_oxygenase PF13434.6 AIM19665.1 - 1.8e-105 352.9 0.0 2.1e-105 352.6 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 AIM19665.1 - 1.1e-11 44.6 0.0 8.4e-10 38.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 AIM19665.1 - 3.8e-05 23.1 0.0 0.028 13.7 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 AIM19665.1 - 0.00012 22.2 0.3 0.8 9.7 0.0 3.4 2 1 1 3 3 3 2 FAD-NAD(P)-binding FMO-like PF00743.19 AIM19665.1 - 0.0029 16.1 0.0 0.016 13.7 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like MnmE_helical PF12631.7 AIM19666.1 - 1.6e-60 204.8 1.5 2e-60 204.5 1.5 1.1 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 AIM19666.1 - 2.8e-35 121.1 0.0 1e-34 119.3 0.0 2.0 2 0 0 2 2 2 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 AIM19666.1 - 9.5e-25 86.9 0.0 3.4e-24 85.1 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AIM19666.1 - 5.6e-08 32.5 0.0 1.8e-07 30.8 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 AIM19666.1 - 2.8e-05 24.2 0.0 0.00068 19.7 0.0 2.3 1 1 1 2 2 2 1 Dynamin family AIG1 PF04548.16 AIM19666.1 - 0.00016 21.1 0.0 0.00029 20.2 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Ras PF00071.22 AIM19666.1 - 0.00042 19.9 0.0 0.00074 19.2 0.0 1.5 1 0 0 1 1 1 1 Ras family RsgA_GTPase PF03193.16 AIM19666.1 - 0.00072 19.5 0.0 0.0098 15.8 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 AIM19666.1 - 0.0012 19.3 0.0 0.0025 18.3 0.0 1.6 1 0 0 1 1 1 1 ABC transporter Roc PF08477.13 AIM19666.1 - 0.0064 16.7 0.0 0.017 15.3 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 AIM19666.1 - 0.0096 16.2 0.0 0.024 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 AIM19666.1 - 0.012 15.2 0.0 0.9 9.0 0.0 2.4 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Arf PF00025.21 AIM19666.1 - 0.016 14.7 0.0 0.043 13.3 0.0 1.8 1 1 0 1 1 1 0 ADP-ribosylation factor family SRPRB PF09439.10 AIM19666.1 - 0.017 14.6 0.0 0.034 13.6 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 AIM19666.1 - 0.028 13.8 0.0 0.076 12.4 0.0 1.7 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region YidC_periplas PF14849.6 AIM19667.1 - 3e-86 289.8 3.1 3.9e-86 289.4 3.1 1.1 1 0 0 1 1 1 1 YidC periplasmic domain 60KD_IMP PF02096.20 AIM19667.1 - 2.7e-61 206.3 15.1 4.5e-61 205.6 15.1 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein DUF2427 PF10348.9 AIM19667.1 - 2.4 8.0 6.2 0.26 11.1 1.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) YidD PF01809.18 AIM19668.1 - 8.3e-30 102.5 0.0 9.5e-30 102.3 0.0 1.0 1 0 0 1 1 1 1 Putative membrane protein insertion efficiency factor Ribonuclease_P PF00825.18 AIM19669.1 - 1.4e-32 112.0 0.2 1.6e-32 111.9 0.2 1.0 1 0 0 1 1 1 1 Ribonuclease P Ribosomal_L34 PF00468.17 AIM19670.1 - 1.8e-24 85.4 9.8 2e-24 85.3 9.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L34 Bac_DnaA PF00308.18 AIM19671.1 - 4.1e-99 330.9 0.2 6.2e-99 330.3 0.2 1.3 1 0 0 1 1 1 1 Bacterial dnaA protein Bac_DnaA_C PF08299.11 AIM19671.1 - 4.5e-33 113.1 0.3 1.3e-32 111.6 0.1 1.9 2 0 0 2 2 2 1 Bacterial dnaA protein helix-turn-helix DnaA_N PF11638.8 AIM19671.1 - 9.4e-21 73.3 0.2 2.3e-20 72.1 0.2 1.7 1 0 0 1 1 1 1 DnaA N-terminal domain IstB_IS21 PF01695.17 AIM19671.1 - 3.8e-11 43.0 0.0 7e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA PF00004.29 AIM19671.1 - 1.7e-06 28.5 0.0 9.1e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Kinesin PF00225.23 AIM19671.1 - 0.00028 19.9 0.0 0.00063 18.8 0.0 1.6 1 1 0 1 1 1 1 Kinesin motor domain AAA_16 PF13191.6 AIM19671.1 - 0.0014 19.1 0.2 0.009 16.4 0.2 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 AIM19671.1 - 0.0014 18.7 0.1 0.021 14.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 AIM19671.1 - 0.012 15.9 3.6 2.3 8.5 1.6 3.4 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 AIM19671.1 - 0.021 14.7 0.1 0.076 12.9 0.1 1.8 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 AIM19671.1 - 0.034 14.1 0.0 0.076 12.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AFG1_ATPase PF03969.16 AIM19671.1 - 0.055 12.4 0.4 0.15 10.9 0.4 1.7 1 1 0 1 1 1 0 AFG1-like ATPase BLOC1S3 PF15753.5 AIM19671.1 - 0.1 12.7 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 RNA_helicase PF00910.22 AIM19671.1 - 0.13 12.7 0.0 0.44 11.0 0.0 2.0 1 1 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 AIM19671.1 - 0.16 12.3 0.2 0.59 10.5 0.1 2.1 1 1 0 1 1 1 0 AAA domain DNA_pol3_beta_2 PF02767.16 AIM19672.1 - 4e-47 159.2 0.0 2.3e-40 137.4 0.0 3.1 3 0 0 3 3 3 2 DNA polymerase III beta subunit, central domain DNA_pol3_beta PF00712.19 AIM19672.1 - 5.9e-45 152.3 0.0 9.5e-39 132.3 0.0 3.1 3 0 0 3 3 3 3 DNA polymerase III beta subunit, N-terminal domain DNA_pol3_beta_3 PF02768.15 AIM19672.1 - 3e-44 149.7 0.6 5.6e-44 148.9 0.1 1.7 2 0 0 2 2 2 1 DNA polymerase III beta subunit, C-terminal domain SMC_N PF02463.19 AIM19673.1 - 8.4e-39 133.3 0.0 1.1e-38 133.0 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AIM19673.1 - 1.4e-08 34.9 0.1 2.3e-05 24.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AIM19673.1 - 3.9e-08 33.4 0.0 4.9e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 AIM19673.1 - 2.3e-07 31.5 0.1 1.4e-06 29.0 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_27 PF13514.6 AIM19673.1 - 7.7e-06 25.6 0.0 1.5e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AIM19673.1 - 0.0019 17.9 0.0 0.0084 15.8 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.27 AIM19673.1 - 0.036 14.6 0.0 0.1 13.1 0.0 1.8 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.6 AIM19673.1 - 0.13 12.6 3.6 0.44 10.9 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain DNA_gyraseB PF00204.25 AIM19674.1 - 5.1e-60 201.9 0.1 9.4e-60 201.0 0.1 1.5 1 0 0 1 1 1 1 DNA gyrase B GyrB_insert PF18053.1 AIM19674.1 - 7.2e-53 178.9 0.0 1.4e-52 178.0 0.0 1.5 1 0 0 1 1 1 1 DNA gyrase B subunit insert domain DNA_gyraseB_C PF00986.21 AIM19674.1 - 9.8e-31 105.7 1.2 1.7e-30 105.0 0.2 1.9 2 0 0 2 2 2 1 DNA gyrase B subunit, carboxyl terminus HATPase_c PF02518.26 AIM19674.1 - 2e-22 79.8 0.2 4.3e-22 78.7 0.2 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 AIM19674.1 - 9.9e-18 64.3 0.0 2.4e-17 63.0 0.0 1.7 1 0 0 1 1 1 1 Toprim domain HATPase_c_3 PF13589.6 AIM19674.1 - 0.00037 20.3 0.1 0.00092 19.1 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Hydrolase_3 PF08282.12 AIM19675.1 - 1.2e-68 231.6 0.0 1.4e-68 231.4 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 AIM19675.1 - 4.2e-18 65.8 0.0 4.4e-10 39.5 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 AIM19675.1 - 9.7e-07 29.3 2.9 0.34 11.2 0.0 3.6 2 2 2 4 4 4 3 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AIM19675.1 - 0.00027 21.0 0.0 0.00068 19.7 0.0 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 AIM19675.1 - 0.0062 17.0 3.4 0.069 13.5 0.3 3.3 1 1 2 4 4 4 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 AIM19675.1 - 0.013 15.6 0.3 7.1 6.7 0.1 2.9 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase OCD_Mu_crystall PF02423.15 AIM19676.1 - 3.1e-64 216.9 0.1 3.3e-64 216.8 0.1 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 AIM19676.1 - 0.00016 21.8 0.0 0.00033 20.7 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 AIM19676.1 - 0.14 11.8 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain PALP PF00291.25 AIM19677.1 - 2.7e-81 273.2 3.6 3.1e-81 273.0 3.6 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ETF PF01012.21 AIM19677.1 - 0.12 12.3 2.4 0.12 12.2 0.3 1.9 2 0 0 2 2 2 0 Electron transfer flavoprotein domain DUF3748 PF12566.8 AIM19678.1 - 2.2e-59 198.8 0.5 1.6e-57 192.8 0.3 3.5 5 0 0 5 5 5 1 Protein of unknown function (DUF3748) PD40 PF07676.12 AIM19678.1 - 3.3e-09 36.5 4.4 0.0058 16.5 0.0 5.1 5 1 0 5 5 5 3 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 AIM19678.1 - 5.7e-05 22.0 0.0 0.83 8.3 0.0 4.5 3 1 1 4 4 4 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Gmad1 PF10647.9 AIM19678.1 - 0.0013 18.6 0.7 0.0031 17.3 0.1 1.9 2 0 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain Proteasome_A_N PF10584.9 AIM19678.1 - 1.3 8.7 8.5 8 6.2 0.0 3.8 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature DUF1375 PF07119.12 AIM19679.1 - 9.9e-12 45.1 2.9 1.5e-11 44.5 2.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1375) HSP20 PF00011.21 AIM19680.1 - 1.1e-20 73.7 0.1 1.3e-20 73.4 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 AIM19680.1 - 3.5e-05 23.3 0.0 5.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA HSP20 PF00011.21 AIM19681.1 - 1.3e-15 57.4 0.0 1.6e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 AIM19681.1 - 1.5e-05 24.4 0.0 3.9e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Asp-Al_Ex PF06826.12 AIM19682.1 - 1.3e-89 298.3 41.7 1.5e-45 155.1 14.1 2.2 2 0 0 2 2 2 2 Predicted Permease Membrane Region TrkA_C PF02080.21 AIM19682.1 - 2e-18 66.0 1.2 8.7e-11 41.5 0.4 2.5 2 0 0 2 2 2 2 TrkA-C domain Castor_Poll_mid PF06241.12 AIM19682.1 - 0.082 12.9 0.0 0.27 11.2 0.0 1.8 2 0 0 2 2 2 0 Castor and Pollux, part of voltage-gated ion channel PIN PF01850.21 AIM19683.1 - 1.1e-12 48.5 0.0 1.3e-12 48.3 0.0 1.0 1 0 0 1 1 1 1 PIN domain DUF5615 PF18480.1 AIM19683.1 - 0.015 15.0 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) PIN_12 PF16289.5 AIM19683.1 - 0.06 13.8 0.0 3.8 8.0 0.0 2.2 1 1 0 2 2 2 0 PIN domain RHH_1 PF01402.21 AIM19684.1 - 2.7e-07 30.3 0.3 3.4e-07 30.0 0.3 1.1 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family RHH_3 PF12651.7 AIM19684.1 - 0.0014 18.6 0.1 0.0021 18.0 0.1 1.2 1 0 0 1 1 1 1 Ribbon-helix-helix domain Aminotran_1_2 PF00155.21 AIM19685.1 - 9.5e-23 80.9 0.0 7.2e-22 78.0 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 AIM19685.1 - 0.0087 14.9 0.0 0.021 13.6 0.0 1.6 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Beta_elim_lyase PF01212.21 AIM19685.1 - 0.047 13.0 0.0 0.093 12.0 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase 2OG-Fe_Oxy_2 PF10014.9 AIM19686.1 - 5.6e-36 124.1 0.0 6.9e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe dioxygenase Cys_Met_Meta_PP PF01053.20 AIM19687.1 - 1.6e-70 237.6 0.0 1.7e-70 237.5 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SelA PF03841.13 AIM19687.1 - 0.04 12.9 0.1 0.13 11.2 0.0 1.6 1 1 0 2 2 2 0 L-seryl-tRNA selenium transferase APH PF01636.23 AIM19688.1 - 1.2e-18 67.9 0.0 1.7e-18 67.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 AIM19688.1 - 1.3e-05 24.9 0.5 6.9e-05 22.5 0.5 2.0 1 1 0 1 1 1 1 Choline/ethanolamine kinase ATP-grasp_3 PF02655.14 AIM19689.1 - 0.0029 17.7 0.0 0.0051 16.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 AIM19689.1 - 0.0064 16.3 0.2 0.0085 15.9 0.2 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_YheCD PF14398.6 AIM19689.1 - 0.084 12.1 0.1 0.12 11.6 0.1 1.2 1 0 0 1 1 1 0 YheC/D like ATP-grasp DUF3791 PF12668.7 AIM19689.1 - 0.11 12.6 0.0 11 6.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3791) GSH-S_ATP PF02955.16 AIM19689.1 - 0.15 11.5 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain ATP-grasp_4 PF13535.6 AIM19690.1 - 0.069 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain EamA PF00892.20 AIM19691.1 - 2.8e-07 30.8 43.5 0.00055 20.1 11.2 2.6 1 1 0 2 2 2 2 EamA-like transporter family 2-Hacid_dh_C PF02826.19 AIM19692.1 - 3.3e-62 209.0 0.0 2e-61 206.5 0.0 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 AIM19692.1 - 6.7e-28 97.0 0.0 7.8e-28 96.8 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 AIM19692.1 - 0.0009 19.4 0.1 0.008 16.4 0.0 2.2 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 AIM19692.1 - 0.8 10.3 2.5 1 10.0 0.2 2.4 2 2 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent MFS_1 PF07690.16 AIM19693.1 - 8.4e-70 235.4 74.0 1.1e-57 195.6 41.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AIM19693.1 - 3.2e-08 32.9 29.7 4.4e-08 32.4 29.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter ATG22 PF11700.8 AIM19693.1 - 1.5e-06 27.1 22.1 1.8e-06 26.9 17.8 2.0 1 1 1 2 2 2 1 Vacuole effluxer Atg22 like MFS_4 PF06779.14 AIM19693.1 - 0.00046 19.6 31.4 0.011 15.0 31.4 2.0 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB PfkB PF00294.24 AIM19694.1 - 1.6e-62 211.5 0.7 2e-62 211.2 0.7 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 AIM19694.1 - 0.00093 18.6 1.0 0.0015 18.0 0.0 1.7 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase AP_endonuc_2 PF01261.24 AIM19695.1 - 1.2e-05 24.9 0.3 3.1e-05 23.5 0.1 1.8 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel Peripla_BP_3 PF13377.6 AIM19696.1 - 4e-23 82.5 0.2 4e-20 72.8 0.1 2.4 2 0 0 2 2 2 2 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 AIM19696.1 - 2.3e-20 73.2 0.1 3.2e-20 72.7 0.1 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_4 PF13407.6 AIM19696.1 - 1e-15 58.0 0.0 1.4e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain LacI PF00356.21 AIM19696.1 - 4e-12 45.7 0.0 2.8e-10 39.8 0.0 3.0 3 0 0 3 3 3 1 Bacterial regulatory proteins, lacI family CbiJ PF02571.14 AIM19696.1 - 0.0068 15.9 0.0 0.057 12.9 0.0 2.1 1 1 1 2 2 2 1 Precorrin-6x reductase CbiJ/CobK Rad10 PF03834.14 AIM19696.1 - 0.014 15.4 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) OmpA PF00691.20 AIM19697.1 - 4.6e-22 78.2 0.2 6.8e-22 77.7 0.2 1.2 1 0 0 1 1 1 1 OmpA family Gly-zipper_Omp PF13488.6 AIM19697.1 - 4.2e-11 42.7 17.5 4.2e-11 42.7 17.5 1.9 2 0 0 2 2 2 1 Glycine zipper Gly-zipper_YMGG PF13441.6 AIM19697.1 - 2.2e-09 36.9 20.0 2.2e-09 36.9 20.0 2.0 2 0 0 2 2 2 1 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.15 AIM19697.1 - 0.00015 21.5 21.3 0.00015 21.5 21.3 2.3 3 0 0 3 3 3 1 Glycine zipper 2TM domain TraT PF05818.12 AIM19697.1 - 0.75 9.4 8.6 1.1 8.9 8.6 1.4 1 1 0 1 1 1 0 Enterobacterial TraT complement resistance protein YtxH PF12732.7 AIM19697.1 - 6.5 7.4 17.6 0.72 10.4 2.1 2.8 2 1 0 2 2 2 0 YtxH-like protein Acetyltransf_10 PF13673.7 AIM19698.1 - 2.2e-20 72.9 0.1 2.8e-20 72.5 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AIM19698.1 - 1.4e-14 54.3 0.2 1.7e-14 54.0 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AIM19698.1 - 7e-14 52.0 0.2 1.1e-13 51.3 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AIM19698.1 - 3.4e-05 23.7 0.1 6.3e-05 22.9 0.1 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 AIM19698.1 - 0.0093 16.1 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 AIM19698.1 - 0.0098 16.0 0.2 0.063 13.4 0.2 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AIM19698.1 - 0.013 15.6 0.1 0.026 14.7 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AIM19698.1 - 0.021 15.5 0.1 0.033 14.8 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Adenine_glyco PF03352.13 AIM19699.1 - 3.3e-82 274.5 0.0 3.7e-82 274.4 0.0 1.0 1 0 0 1 1 1 1 Methyladenine glycosylase Osmo_MPGsynth PF09488.10 AIM19699.1 - 0.019 13.7 0.0 0.027 13.2 0.0 1.1 1 0 0 1 1 1 0 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) HhH-GPD PF00730.25 AIM19699.1 - 0.062 13.8 0.1 0.092 13.2 0.1 1.2 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein Autotransporter PF03797.19 AIM19700.1 - 8.3e-47 160.0 24.1 2.3e-46 158.5 24.1 1.8 1 0 0 1 1 1 1 Autotransporter beta-domain Lipase_GDSL PF00657.22 AIM19700.1 - 9.8e-11 42.0 0.5 2.3e-10 40.8 0.5 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Autoind_bind PF03472.15 AIM19701.1 - 1.3e-21 76.7 0.0 1.7e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 Autoinducer binding domain GerE PF00196.19 AIM19701.1 - 3e-14 52.3 0.3 1.1e-13 50.4 0.0 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AIM19701.1 - 1.2e-07 31.3 0.0 2.1e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AIM19701.1 - 0.003 17.1 0.0 0.0062 16.0 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_10 PF04967.12 AIM19701.1 - 0.015 15.1 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain HTH_24 PF13412.6 AIM19701.1 - 0.017 14.6 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_40 PF14493.6 AIM19701.1 - 0.078 13.4 0.2 0.25 11.8 0.1 1.9 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_38 PF13936.6 AIM19701.1 - 0.12 12.2 0.1 0.29 11.0 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 AIM19701.1 - 0.2 11.5 0.1 0.54 10.1 0.0 1.7 1 1 0 1 1 1 0 Homeodomain-like domain Autoind_synth PF00765.17 AIM19702.1 - 2.8e-65 219.3 0.0 3.2e-65 219.1 0.0 1.0 1 0 0 1 1 1 1 Autoinducer synthase Acetyltransf_5 PF13444.6 AIM19702.1 - 0.029 15.1 0.0 0.046 14.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain tRNA-synt_2e PF02091.15 AIM19703.1 - 3.8e-150 498.7 0.0 4.4e-150 498.5 0.0 1.0 1 0 0 1 1 1 1 Glycyl-tRNA synthetase alpha subunit tRNA_synt_2f PF02092.17 AIM19704.1 - 5e-210 699.0 0.7 5.4e-210 698.8 0.0 1.4 2 0 0 2 2 2 1 Glycyl-tRNA synthetase beta subunit DALR_1 PF05746.15 AIM19704.1 - 9.6e-08 32.2 1.8 2.5e-07 30.9 1.8 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain Fic PF02661.18 AIM19705.1 - 9e-16 58.6 0.0 1.9e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 Fic/DOC family DUF3053 PF11254.8 AIM19706.1 - 7.3e-97 323.3 14.4 8.3e-97 323.1 14.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3053) DUF3600 PF12207.8 AIM19706.1 - 0.06 13.3 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3600) Snapin_Pallidin PF14712.6 AIM19706.1 - 0.38 11.2 8.0 0.22 12.0 0.3 2.8 3 1 0 3 3 3 0 Snapin/Pallidin PTS_EIIA_2 PF00359.22 AIM19707.1 - 3.2e-33 114.7 0.0 6.4e-33 113.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 PTS_EIIC PF02378.18 AIM19707.1 - 2.2e-19 69.7 32.7 2.2e-19 69.7 32.7 2.7 2 1 0 2 2 2 1 Phosphotransferase system, EIIC PTS_IIB PF02302.17 AIM19707.1 - 1.6e-10 41.5 0.0 3.4e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 PTS system, Lactose/Cellobiose specific IIB subunit Mannitol_dh_C PF08125.13 AIM19708.1 - 2.4e-65 220.4 0.0 3.4e-65 220.0 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 AIM19708.1 - 2.1e-25 89.7 0.2 7.7e-25 87.8 0.2 1.9 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain 3HCDH_N PF02737.18 AIM19708.1 - 0.0011 18.9 0.3 0.0039 17.1 0.2 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 AIM19708.1 - 0.0011 18.6 0.3 0.0022 17.7 0.3 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 AIM19708.1 - 0.003 17.1 0.2 0.0051 16.4 0.2 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 AIM19708.1 - 0.019 15.3 0.5 0.04 14.2 0.5 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ApbA_C PF08546.11 AIM19708.1 - 0.11 12.7 0.1 0.79 9.9 0.0 2.4 3 1 0 3 3 3 0 Ketopantoate reductase PanE/ApbA C terminal MtlR PF05068.12 AIM19709.1 - 2.7e-62 209.6 0.0 3.2e-62 209.4 0.0 1.0 1 0 0 1 1 1 1 Mannitol repressor DUF5505 PF17610.2 AIM19709.1 - 0.19 11.7 0.1 0.28 11.2 0.1 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5505) LysE PF01810.18 AIM19710.1 - 2.1e-12 46.9 12.6 2.5e-12 46.7 12.6 1.0 1 0 0 1 1 1 1 LysE type translocator DUF808 PF05661.12 AIM19710.1 - 0.093 11.8 0.3 0.14 11.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF808) Aminotran_1_2 PF00155.21 AIM19711.1 - 1.1e-25 90.6 0.0 2e-25 89.8 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class I and II GntR PF00392.21 AIM19711.1 - 6.4e-15 54.6 1.1 1.8e-14 53.1 0.1 2.4 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family DUF2810 PF10928.8 AIM19712.1 - 1.2e-32 111.6 0.5 2.2e-32 110.8 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2810) Tup_N PF08581.10 AIM19712.1 - 0.014 15.7 1.6 0.052 13.9 0.3 2.2 1 1 1 2 2 2 0 Tup N-terminal RsmJ PF04378.13 AIM19712.1 - 0.029 13.6 0.1 0.032 13.4 0.1 1.1 1 0 0 1 1 1 0 Ribosomal RNA large subunit methyltransferase D, RlmJ FlgN PF05130.12 AIM19712.1 - 0.039 14.5 5.8 0.051 14.1 5.8 1.2 1 0 0 1 1 1 0 FlgN protein Rnk_N PF14760.6 AIM19712.1 - 0.16 12.4 1.0 1.6 9.3 1.0 2.3 1 1 0 1 1 1 0 Rnk N-terminus Methyltransf_11 PF08241.12 AIM19713.1 - 6.7e-21 74.7 0.0 1.2e-20 74.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AIM19713.1 - 7.9e-19 68.2 0.0 3.1e-18 66.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIM19713.1 - 3.7e-11 43.6 0.0 1e-10 42.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 AIM19713.1 - 1.9e-10 40.8 0.0 2.7e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AIM19713.1 - 2.6e-09 37.1 0.0 3.9e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AIM19713.1 - 6.3e-07 29.0 0.0 1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 AIM19713.1 - 6e-06 26.3 0.0 1.2e-05 25.2 0.0 1.5 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_29 PF03141.16 AIM19713.1 - 0.00046 18.9 0.0 0.0006 18.5 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.20 AIM19713.1 - 0.00063 18.9 0.0 0.0011 18.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase FtsJ PF01728.19 AIM19713.1 - 0.0028 17.8 0.0 0.0043 17.2 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.19 AIM19713.1 - 0.013 15.3 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 AIM19713.1 - 0.017 14.7 0.0 0.04 13.5 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_PK PF05891.12 AIM19713.1 - 0.022 14.3 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase DREV PF05219.12 AIM19713.1 - 0.087 11.9 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_9 PF08003.11 AIM19713.1 - 0.15 11.0 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) MOSC PF03473.17 AIM19714.1 - 1.8e-21 76.5 0.0 2.8e-21 75.9 0.0 1.3 1 1 0 1 1 1 1 MOSC domain 3-alpha PF03475.14 AIM19714.1 - 1.3e-16 60.1 0.3 2.5e-16 59.3 0.3 1.5 1 0 0 1 1 1 1 3-alpha domain His_Phos_1 PF00300.22 AIM19715.1 - 1e-50 172.1 0.2 1.2e-50 172.0 0.2 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) MCPsignal PF00015.21 AIM19716.1 - 1.9e-54 184.1 19.8 1.9e-54 184.1 19.8 4.3 3 1 3 6 6 6 3 Methyl-accepting chemotaxis protein (MCP) signalling domain HBM PF16591.5 AIM19716.1 - 5.9e-15 55.4 20.1 5.9e-15 55.4 20.1 3.9 2 1 0 3 3 3 1 Helical bimodular sensor domain HAMP PF00672.25 AIM19716.1 - 7.6e-08 32.6 2.6 7.6e-08 32.6 2.6 5.2 6 0 0 6 6 6 1 HAMP domain RasGAP_C PF03836.15 AIM19716.1 - 0.015 15.4 4.0 0.022 14.9 1.2 2.6 2 0 0 2 2 2 0 RasGAP C-terminus 4HB_MCP_1 PF12729.7 AIM19716.1 - 0.084 12.4 0.2 0.084 12.4 0.2 5.9 3 3 4 8 8 8 0 Four helix bundle sensory module for signal transduction DUF948 PF06103.11 AIM19716.1 - 1.2 9.4 29.1 12 6.3 5.3 5.9 2 2 3 5 5 5 0 Bacterial protein of unknown function (DUF948) Sod_Fe_C PF02777.18 AIM19717.1 - 1.6e-41 140.6 0.3 4.7e-41 139.1 0.1 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 AIM19717.1 - 2.2e-32 111.4 3.7 3.7e-32 110.6 3.7 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain HTH_54 PF18607.1 AIM19717.1 - 0.065 13.3 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 ParA helix turn helix domain Molybdop_Fe4S4 PF04879.16 AIM19718.1 - 7.8e-20 70.6 0.1 1.8e-19 69.4 0.1 1.7 2 0 0 2 2 2 1 Molybdopterin oxidoreductase Fe4S4 domain Molybdopterin PF00384.22 AIM19718.1 - 3.6e-06 26.2 0.0 4e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin oxidoreductase TAT_signal PF10518.9 AIM19718.1 - 0.00015 21.4 1.2 0.0005 19.8 1.2 1.9 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence Rieske_3 PF18465.1 AIM19718.1 - 0.0083 16.4 0.6 0.43 10.9 0.5 2.8 2 1 1 3 3 3 1 Rieske 3Fe-4S Molybdopterin PF00384.22 AIM19719.1 - 3.3e-26 92.2 0.0 1.2e-23 83.8 0.0 2.3 2 0 0 2 2 2 2 Molybdopterin oxidoreductase Molydop_binding PF01568.21 AIM19719.1 - 8e-18 64.5 0.1 1.9e-17 63.3 0.1 1.7 1 1 0 1 1 1 1 Molydopterin dinucleotide binding domain Fer4_11 PF13247.6 AIM19720.1 - 3.4e-25 88.1 8.8 3.4e-25 88.1 8.8 1.6 2 0 0 2 2 2 1 4Fe-4S dicluster domain Form-deh_trans PF09163.11 AIM19720.1 - 5.1e-23 80.6 0.6 1e-22 79.6 0.6 1.5 1 0 0 1 1 1 1 Formate dehydrogenase N, transmembrane Fer4_7 PF12838.7 AIM19720.1 - 5.4e-15 55.7 23.6 3.2e-08 34.0 5.1 3.2 2 1 1 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 AIM19720.1 - 4.3e-12 46.0 25.1 6.2e-07 29.4 9.8 3.6 2 1 2 4 4 4 4 4Fe-4S dicluster domain Fer4_9 PF13187.6 AIM19720.1 - 4.6e-12 45.9 24.0 5.8e-06 26.4 9.5 2.7 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 AIM19720.1 - 1.4e-07 31.5 26.5 3.8e-06 26.9 7.0 3.8 3 1 0 3 3 3 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 AIM19720.1 - 3.9e-07 29.9 34.6 0.0039 17.2 2.8 4.9 4 1 0 4 4 4 4 4Fe-4S binding domain Fer4_2 PF12797.7 AIM19720.1 - 4.1e-07 29.7 28.1 0.0046 17.0 1.0 4.4 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4 PF00037.27 AIM19720.1 - 4.4e-07 29.4 36.2 6.2e-05 22.6 2.6 5.4 6 0 0 6 6 6 3 4Fe-4S binding domain Fer4_4 PF12800.7 AIM19720.1 - 0.00017 21.8 33.0 0.015 15.7 2.6 4.5 4 1 0 4 4 4 2 4Fe-4S binding domain Fer4_16 PF13484.6 AIM19720.1 - 0.00025 21.9 27.6 0.22 12.5 0.0 5.0 2 1 3 6 6 6 2 4Fe-4S double cluster binding domain Fer4_3 PF12798.7 AIM19720.1 - 0.00026 21.7 39.0 0.31 12.1 3.1 4.4 4 0 0 4 4 4 4 4Fe-4S binding domain Fer4_17 PF13534.6 AIM19720.1 - 0.00043 20.8 24.8 0.81 10.3 2.1 4.3 2 2 2 4 4 4 3 4Fe-4S dicluster domain Fer4_8 PF13183.6 AIM19720.1 - 0.0035 17.7 28.4 0.17 12.3 8.6 4.0 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer4_22 PF17179.4 AIM19720.1 - 0.0036 18.1 12.4 0.12 13.3 0.6 3.8 4 0 0 4 4 4 2 4Fe-4S dicluster domain Fer4_15 PF13459.6 AIM19720.1 - 0.0049 17.6 13.5 0.16 12.7 0.4 3.6 2 1 0 2 2 2 1 4Fe-4S single cluster domain Fer4_20 PF14691.6 AIM19720.1 - 0.027 14.3 0.3 0.027 14.3 0.3 4.1 2 1 2 4 4 4 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_13 PF13370.6 AIM19720.1 - 0.038 14.5 0.7 0.038 14.5 0.7 4.0 3 1 0 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 AIM19720.1 - 0.11 12.7 23.5 0.2 11.9 4.9 3.9 2 1 2 4 4 4 0 4Fe-4S dicluster domain Ni_hydr_CYTB PF01292.20 AIM19721.1 - 5.1e-22 78.4 16.4 6.2e-22 78.1 16.4 1.1 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 DUF4405 PF14358.6 AIM19721.1 - 0.00032 21.2 29.3 0.016 15.7 11.9 2.8 2 1 1 3 3 3 2 Domain of unknown function (DUF4405) PepSY_TM PF03929.16 AIM19721.1 - 0.009 15.7 1.8 0.009 15.7 1.8 2.1 2 0 0 2 2 2 2 PepSY-associated TM region DBD_Tnp_Hermes PF10683.9 AIM19721.1 - 0.14 11.8 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Hermes transposase DNA-binding domain FdhE PF04216.12 AIM19722.1 - 8.1e-115 383.6 0.1 9.3e-115 383.4 0.1 1.0 1 0 0 1 1 1 1 Protein involved in formate dehydrogenase formation AAA_16 PF13191.6 AIM19722.1 - 0.0021 18.5 1.2 0.025 15.0 0.6 2.2 2 0 0 2 2 2 1 AAA ATPase domain DZR PF12773.7 AIM19722.1 - 0.024 14.7 6.6 0.51 10.4 2.4 2.7 1 1 1 2 2 2 0 Double zinc ribbon Stc1 PF12898.7 AIM19722.1 - 0.028 15.0 3.0 0.048 14.2 3.0 1.4 1 0 0 1 1 1 0 Stc1 domain Rpr2 PF04032.16 AIM19722.1 - 0.068 13.5 0.8 1.5 9.2 0.3 2.6 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-ribbon_3 PF13248.6 AIM19722.1 - 0.18 11.3 6.4 0.58 9.6 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Lar_restr_allev PF14354.6 AIM19722.1 - 0.62 10.5 6.1 8.9 6.8 6.1 2.6 1 1 0 1 1 1 0 Restriction alleviation protein Lar zinc_ribbon_6 PF14599.6 AIM19722.1 - 1.5 8.9 4.8 2.1 8.4 1.8 2.6 2 0 0 2 2 2 0 Zinc-ribbon zinc-ribbons_6 PF07191.12 AIM19722.1 - 2 8.4 6.4 19 5.3 6.3 2.3 1 1 1 2 2 2 0 zinc-ribbons ZZ PF00569.17 AIM19722.1 - 4.8 7.1 6.7 1.2 8.9 3.3 1.8 2 0 0 2 2 2 0 Zinc finger, ZZ type HypA PF01155.19 AIM19722.1 - 8.5 6.4 8.8 9.2 6.3 3.3 2.8 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DcrB PF08786.11 AIM19723.1 - 3.2e-08 33.7 5.7 3.3e-07 30.5 5.7 2.0 1 1 0 1 1 1 1 DcrB Apocytochr_F_N PF16639.5 AIM19723.1 - 0.023 15.0 0.1 0.05 13.9 0.0 1.6 1 1 0 1 1 1 0 Apocytochrome F, N-terminal SMC_N PF02463.19 AIM19723.1 - 0.094 12.1 0.3 0.13 11.6 0.3 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain FAP PF07174.11 AIM19723.1 - 0.39 10.1 11.7 0.57 9.6 11.7 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) GST_N_3 PF13417.6 AIM19724.1 - 5.8e-17 61.9 0.0 9.2e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AIM19724.1 - 4.4e-11 42.9 0.0 8.1e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 AIM19724.1 - 3.8e-07 30.2 0.1 5.5e-07 29.7 0.1 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 AIM19724.1 - 0.00024 21.4 0.0 0.00051 20.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 AIM19724.1 - 0.0023 18.1 0.0 0.0036 17.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 AIM19724.1 - 0.033 14.2 0.1 0.056 13.5 0.1 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SelA PF03841.13 AIM19725.1 - 1.4e-171 570.5 0.0 1.6e-171 570.3 0.0 1.0 1 0 0 1 1 1 1 L-seryl-tRNA selenium transferase Se-cys_synth_N PF12390.8 AIM19725.1 - 1.5e-08 34.7 0.4 1.5e-08 34.7 0.4 3.7 4 0 0 4 4 4 1 Selenocysteine synthase N terminal Aminotran_5 PF00266.19 AIM19725.1 - 5.5e-06 25.6 0.1 1.4e-05 24.3 0.1 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 AIM19725.1 - 0.0023 16.6 0.0 0.0061 15.1 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme PKS_DE PF18369.1 AIM19725.1 - 0.43 11.2 4.7 25 5.5 1.0 3.2 2 0 0 2 2 2 0 Polyketide synthase dimerisation element domain GTP_EFTU PF00009.27 AIM19726.1 - 2.2e-31 108.9 0.0 1.1e-30 106.6 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SelB-wing_3 PF09107.11 AIM19726.1 - 3e-19 68.4 0.7 7.3e-19 67.1 0.7 1.7 1 0 0 1 1 1 1 Elongation factor SelB, winged helix SelB-wing_2 PF09106.11 AIM19726.1 - 3.4e-16 59.2 4.4 6.5e-16 58.3 2.4 2.7 2 0 0 2 2 2 1 Elongation factor SelB, winged helix GTP_EFTU_D2 PF03144.25 AIM19726.1 - 1.1e-06 28.9 0.2 2.2e-06 27.9 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 AIM19726.1 - 1.9e-05 24.7 0.0 4.3e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 AIM19726.1 - 0.0011 18.8 0.1 0.0024 17.8 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 4 SRPRB PF09439.10 AIM19726.1 - 0.19 11.1 0.0 0.35 10.3 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RHH_1 PF01402.21 AIM19727.1 - 6e-12 45.1 0.0 1.2e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family HTH_Tnp_Tc3_1 PF11427.8 AIM19727.1 - 0.11 12.4 0.0 0.59 10.0 0.0 1.9 2 0 0 2 2 2 0 Tc3 transposase Glyco_trans_1_2 PF13524.6 AIM19727.1 - 0.16 12.4 0.8 0.36 11.2 0.5 1.6 2 0 0 2 2 2 0 Glycosyl transferases group 1 ParE_toxin PF05016.15 AIM19728.1 - 1.8e-15 57.3 0.4 1.9e-15 57.2 0.4 1.0 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE MFS_1 PF07690.16 AIM19729.1 - 1.1e-29 103.5 42.4 1.1e-29 103.5 42.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Acyl_transf_3 PF01757.22 AIM19730.1 - 1e-28 100.4 37.5 1.2e-28 100.2 37.5 1.0 1 0 0 1 1 1 1 Acyltransferase family DJ-1_PfpI PF01965.24 AIM19731.1 - 1.3e-13 51.1 0.0 1.7e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family HTH_18 PF12833.7 AIM19731.1 - 3.1e-12 46.6 5.3 3.3e-12 46.5 3.7 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 AIM19731.1 - 7.9e-09 35.4 0.0 1.7e-06 28.0 0.0 2.6 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family TetR_N PF00440.23 AIM19731.1 - 0.029 14.2 0.0 0.25 11.1 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family HTH_23 PF13384.6 AIM19731.1 - 0.072 12.9 0.1 0.072 12.9 0.1 2.7 3 0 0 3 3 3 0 Homeodomain-like domain Isochorismatase PF00857.20 AIM19732.1 - 2.1e-21 76.9 0.1 2.7e-21 76.5 0.1 1.2 1 0 0 1 1 1 1 Isochorismatase family Amidohydro_3 PF07969.11 AIM19733.1 - 1.3e-16 61.1 0.6 1.3e-09 38.1 0.3 2.1 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 AIM19733.1 - 3e-07 30.1 0.1 5.7e-07 29.2 0.1 1.4 1 1 0 1 1 1 1 Amidohydrolase family NTP_transf_2 PF01909.23 AIM19734.1 - 1.5e-06 28.4 0.0 2.2e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 AIM19734.1 - 1.7e-06 28.0 0.0 3e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase HTH_20 PF12840.7 AIM19734.1 - 5.1e-05 23.3 0.9 0.00021 21.3 1.0 1.9 2 1 0 2 2 2 1 Helix-turn-helix domain Penicillinase_R PF03965.16 AIM19734.1 - 0.02 15.2 0.0 0.087 13.2 0.0 1.9 2 0 0 2 2 2 0 Penicillinase repressor HTH_IclR PF09339.10 AIM19734.1 - 0.025 14.4 0.9 0.046 13.5 0.9 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain Rrf2 PF02082.20 AIM19734.1 - 0.088 13.2 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator MarR_2 PF12802.7 AIM19734.1 - 0.088 12.7 0.9 0.15 12.0 0.9 1.4 1 0 0 1 1 1 0 MarR family DUF1495 PF07381.11 AIM19734.1 - 0.11 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain (DUF1495) RepL PF05732.11 AIM19734.1 - 0.22 11.0 0.0 0.33 10.4 0.0 1.2 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) HTH_1 PF00126.27 AIM19736.1 - 8.6e-22 76.9 0.2 2.1e-21 75.6 0.2 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 AIM19736.1 - 1.9e-20 73.1 6.3 3.1e-20 72.4 6.3 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_30 PF13556.6 AIM19736.1 - 0.00024 20.8 0.0 0.00077 19.2 0.0 1.8 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain HTH_24 PF13412.6 AIM19736.1 - 0.00029 20.3 0.0 0.0006 19.3 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 AIM19736.1 - 0.01 15.7 0.1 0.027 14.3 0.1 1.8 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain MarR_2 PF12802.7 AIM19736.1 - 0.021 14.7 0.4 0.071 13.0 0.1 2.1 2 0 0 2 2 2 0 MarR family Fe_dep_repress PF01325.19 AIM19736.1 - 0.18 12.1 0.1 0.4 10.9 0.1 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain MFS_1 PF07690.16 AIM19737.1 - 9.8e-25 87.2 62.6 3.4e-24 85.5 49.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 AIM19737.1 - 3.5e-11 43.0 36.0 4.5e-11 42.7 36.0 1.0 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 AIM19737.1 - 0.00041 19.3 4.4 0.00041 19.3 4.4 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter Phytase-like PF13449.6 AIM19738.1 - 8.1e-67 226.2 0.0 9.6e-67 225.9 0.0 1.1 1 0 0 1 1 1 1 Esterase-like activity of phytase Virulence_RhuM PF13310.6 AIM19739.1 - 1.3e-115 385.0 2.4 1.7e-115 384.6 2.4 1.1 1 0 0 1 1 1 1 Virulence protein RhuM family AAA_assoc PF14363.6 AIM19739.1 - 0.03 14.7 0.0 0.096 13.0 0.0 1.9 1 0 0 1 1 1 0 Domain associated at C-terminal with AAA DUF4942 PF13708.6 AIM19740.1 - 0.021 14.8 0.0 0.021 14.8 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4942) DUF1666 PF07891.12 AIM19740.1 - 0.07 12.8 0.0 0.072 12.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1666) DUF962 PF06127.11 AIM19742.1 - 2.2e-26 91.7 0.6 1.6e-25 89.0 0.6 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF962) TauE PF01925.19 AIM19742.1 - 0.023 14.3 18.0 0.032 13.9 18.0 1.1 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE Oxidored_FMN PF00724.20 AIM19743.1 - 7.2e-87 291.8 0.0 8.4e-87 291.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family ApbE PF02424.15 AIM19743.1 - 0.029 13.9 1.0 0.053 13.0 1.0 1.3 1 0 0 1 1 1 0 ApbE family MFS_1 PF07690.16 AIM19744.1 - 5.6e-33 114.3 57.4 2.6e-32 112.1 41.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 AIM19744.1 - 5.9e-10 39.0 41.2 7.6e-10 38.6 41.2 1.0 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 AIM19744.1 - 4.5e-06 25.8 13.9 4.5e-06 25.8 13.9 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter DUF2569 PF10754.9 AIM19744.1 - 0.019 15.4 6.8 0.28 11.6 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2569) Epimerase PF01370.21 AIM19745.1 - 2.2e-18 66.6 0.0 2.7e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AIM19745.1 - 3.4e-13 49.7 0.0 4.3e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 AIM19745.1 - 2.9e-08 33.2 0.1 7.4e-05 22.0 0.1 2.6 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 AIM19745.1 - 1.2e-07 31.9 0.0 1.5e-07 31.5 0.0 1.3 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 AIM19745.1 - 1.4e-07 30.9 0.0 1.8e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 AIM19745.1 - 2.2e-07 30.3 0.0 3.3e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 AIM19745.1 - 3.4e-07 29.6 0.0 4.7e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PTS_EIIA_1 PF00358.20 AIM19746.1 - 1.3e-50 170.4 0.2 2e-50 169.8 0.2 1.3 1 0 0 1 1 1 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 PTS_EIIC PF02378.18 AIM19746.1 - 5.5e-25 88.1 28.5 5.5e-25 88.1 28.5 1.8 1 1 1 2 2 2 1 Phosphotransferase system, EIIC PTS_EIIB PF00367.20 AIM19746.1 - 2.8e-13 49.1 0.3 5.5e-13 48.2 0.3 1.5 1 0 0 1 1 1 1 phosphotransferase system, EIIB Glyco_hydro_1 PF00232.18 AIM19747.1 - 1.5e-160 534.5 0.1 1.7e-160 534.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Cellulase PF00150.18 AIM19747.1 - 0.0014 18.1 0.0 0.0031 17.0 0.0 1.5 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) OprB PF04966.12 AIM19748.1 - 4.6e-68 230.4 5.4 5.5e-68 230.1 5.4 1.1 1 0 0 1 1 1 1 Carbohydrate-selective porin, OprB family HD_4 PF13328.6 AIM19749.1 - 3.2e-18 65.9 0.3 4.5e-18 65.5 0.3 1.2 1 0 0 1 1 1 1 HD domain HD PF01966.22 AIM19749.1 - 0.053 13.7 0.1 0.12 12.6 0.1 1.6 1 1 0 1 1 1 0 HD domain MarR PF01047.22 AIM19750.1 - 4e-16 58.7 0.1 6.4e-16 58.0 0.1 1.3 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 AIM19750.1 - 1.8e-10 40.6 0.2 2.9e-10 39.9 0.2 1.4 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 AIM19750.1 - 2.8e-10 40.5 0.6 9.9e-10 38.8 0.2 1.9 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_34 PF13601.6 AIM19750.1 - 0.0003 20.9 0.1 0.00061 19.9 0.0 1.6 2 0 0 2 2 2 1 Winged helix DNA-binding domain Penicillinase_R PF03965.16 AIM19750.1 - 0.0004 20.7 0.2 0.0011 19.4 0.2 1.7 1 1 0 1 1 1 1 Penicillinase repressor TFIIE_alpha PF02002.17 AIM19750.1 - 0.001 18.9 0.1 0.0026 17.6 0.1 1.8 1 1 0 1 1 1 1 TFIIE alpha subunit HxlR PF01638.17 AIM19750.1 - 0.0011 18.8 0.1 0.0019 18.0 0.1 1.4 1 0 0 1 1 1 1 HxlR-like helix-turn-helix PadR PF03551.14 AIM19750.1 - 0.0018 18.2 0.1 0.0035 17.3 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_20 PF12840.7 AIM19750.1 - 0.0082 16.2 1.6 0.014 15.4 0.2 2.0 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_24 PF13412.6 AIM19750.1 - 0.013 15.0 0.0 0.029 13.9 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Fe_dep_repress PF01325.19 AIM19750.1 - 0.028 14.6 0.0 0.058 13.6 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain TrmB PF01978.19 AIM19750.1 - 0.049 13.5 0.2 0.15 11.9 0.1 1.9 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_micro PF17007.5 AIM19750.1 - 0.18 10.6 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 HTH-like OsmC PF02566.19 AIM19751.1 - 4.4e-16 59.2 0.0 6.8e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 OsmC-like protein DUF826 PF05696.11 AIM19751.1 - 0.026 14.6 0.2 59 3.9 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF826) Sulfatase PF00884.23 AIM19752.1 - 1.4e-43 149.5 0.1 1.9e-43 149.1 0.1 1.2 1 0 0 1 1 1 1 Sulfatase EptA_B_N PF08019.12 AIM19752.1 - 2.3e-18 66.5 13.1 2.3e-18 66.5 13.1 1.8 2 1 0 2 2 2 1 Phosphoethanolamine transferase EptA/EptB Response_reg PF00072.24 AIM19753.1 - 4.5e-22 78.3 0.0 6.6e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AIM19753.1 - 1.1e-19 69.7 0.1 2.2e-19 68.8 0.0 1.5 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family HTH_23 PF13384.6 AIM19753.1 - 1.6e-06 27.8 0.1 4.7e-06 26.2 0.1 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.6 AIM19753.1 - 3.1e-05 23.6 0.2 0.00016 21.4 0.1 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 AIM19753.1 - 0.00012 21.6 0.2 0.00026 20.6 0.1 1.7 1 1 0 1 1 1 1 Sigma-70, region 4 HTH_28 PF13518.6 AIM19753.1 - 0.00021 21.4 0.1 0.00045 20.3 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 AIM19753.1 - 0.00041 20.3 0.0 0.00081 19.4 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix Terminase_5 PF06056.12 AIM19753.1 - 0.008 16.1 0.0 0.028 14.3 0.0 1.9 2 0 0 2 2 2 1 Putative ATPase subunit of terminase (gpP-like) HTH_24 PF13412.6 AIM19753.1 - 0.0088 15.6 0.1 0.029 13.9 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 AIM19753.1 - 0.011 15.6 0.7 0.062 13.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_7 PF02796.15 AIM19753.1 - 0.019 15.0 0.0 0.039 14.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_40 PF14493.6 AIM19753.1 - 0.024 15.1 0.0 0.048 14.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_ECF PF07638.11 AIM19753.1 - 0.026 14.4 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 ECF sigma factor HTH_AsnC-type PF13404.6 AIM19753.1 - 0.034 14.0 0.1 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Sigma70_r4 PF04545.16 AIM19753.1 - 0.061 12.8 0.1 0.13 11.9 0.1 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.6 AIM19753.1 - 0.082 12.3 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 MASE1 PF05231.14 AIM19754.1 - 6.5e-16 58.3 39.1 1.6e-15 57.1 39.1 1.7 1 1 0 1 1 1 1 MASE1 HisKA_3 PF07730.13 AIM19754.1 - 1.5e-10 41.4 5.4 1.9e-10 41.1 0.1 2.6 2 0 0 2 2 2 1 Histidine kinase HATPase_c PF02518.26 AIM19754.1 - 0.00065 20.2 0.0 0.0025 18.3 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2232 PF09991.9 AIM19754.1 - 0.00066 19.0 1.2 0.0024 17.1 0.0 2.3 2 0 0 2 2 2 1 Predicted membrane protein (DUF2232) HATPase_c_2 PF13581.6 AIM19754.1 - 0.0044 17.0 0.1 0.012 15.6 0.0 1.7 1 1 0 2 2 2 1 Histidine kinase-like ATPase domain DUF2955 PF11168.8 AIM19754.1 - 0.015 15.2 2.5 0.016 15.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2955) Thia_YuaJ PF09515.10 AIM19754.1 - 0.038 14.0 0.5 0.081 12.9 0.0 1.8 2 0 0 2 2 2 0 Thiamine transporter protein (Thia_YuaJ) Polysacc_synt_C PF14667.6 AIM19754.1 - 8.6 6.4 20.0 0.024 14.7 5.2 3.0 2 1 2 4 4 4 0 Polysaccharide biosynthesis C-terminal domain MFS_1 PF07690.16 AIM19755.1 - 2.4e-50 171.4 38.7 2.4e-50 171.4 38.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ARL6IP6 PF15062.6 AIM19755.1 - 0.075 13.2 0.2 0.21 11.8 0.2 1.7 1 0 0 1 1 1 0 Haemopoietic lineage transmembrane helix Glyco_hydro_18 PF00704.28 AIM19756.1 - 4.9e-89 299.1 1.4 6.6e-89 298.7 1.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ChitinaseA_N PF08329.10 AIM19756.1 - 2.5e-56 189.0 0.5 4.9e-56 188.1 0.5 1.5 1 0 0 1 1 1 1 Chitinase A, N-terminal domain PKD PF00801.20 AIM19756.1 - 0.0079 16.0 0.3 0.0079 16.0 0.3 1.9 2 0 0 2 2 2 1 PKD domain Ntox23 PF15528.6 AIM19756.1 - 0.045 13.9 0.2 0.13 12.5 0.1 1.8 2 0 0 2 2 2 0 Bacterial toxin 23 DUF1539 PF07560.11 AIM19756.1 - 0.066 13.3 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) Y_Y_Y PF07495.13 AIM19756.1 - 0.12 12.3 0.0 0.52 10.3 0.0 2.1 2 0 0 2 2 2 0 Y_Y_Y domain SBP_bac_5 PF00496.22 AIM19757.1 - 3.9e-106 355.2 8.0 4.6e-106 355.0 8.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle BPD_transp_1 PF00528.22 AIM19758.1 - 1.3e-47 161.9 13.2 1.3e-47 161.9 13.2 1.6 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component UPF0370 PF13980.6 AIM19758.1 - 0.8 9.8 0.0 0.8 9.8 0.0 2.5 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0370) BPD_transp_1 PF00528.22 AIM19759.1 - 8.9e-31 107.1 14.5 1e-30 106.8 12.0 2.1 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 AIM19759.1 - 1.4e-13 50.6 0.1 1.4e-13 50.6 0.1 3.9 4 0 0 4 4 4 2 N-terminal TM domain of oligopeptide transport permease C DUF624 PF04854.14 AIM19759.1 - 0.15 12.2 0.0 0.15 12.2 0.0 3.4 3 1 0 3 3 3 0 Protein of unknown function, DUF624 ABC_tran PF00005.27 AIM19760.1 - 1.9e-27 96.5 0.0 2.5e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 AIM19760.1 - 1.5e-18 67.0 0.3 2.6e-18 66.3 0.3 1.4 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 AIM19760.1 - 3.1e-06 27.2 0.2 4.8e-05 23.3 0.1 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIM19760.1 - 3.4e-06 26.7 0.0 5.3e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AIM19760.1 - 0.014 15.7 2.4 3.4 7.9 0.2 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 AIM19760.1 - 0.19 11.5 0.1 0.4 10.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 AIM19761.1 - 3.1e-31 108.7 0.0 4.4e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 AIM19761.1 - 1.1e-18 67.5 0.3 2.2e-18 66.5 0.3 1.5 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region IstB_IS21 PF01695.17 AIM19761.1 - 0.0032 17.2 0.0 0.0057 16.4 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_21 PF13304.6 AIM19761.1 - 0.0053 16.6 0.1 1 9.1 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 AIM19761.1 - 0.0075 16.6 0.9 0.019 15.3 0.9 1.8 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AIM19761.1 - 0.012 15.5 0.1 0.025 14.5 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 AIM19761.1 - 0.018 15.4 0.0 0.027 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.19 AIM19761.1 - 0.023 14.1 0.0 0.068 12.6 0.0 1.7 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AIM19761.1 - 0.024 14.4 0.1 0.046 13.5 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase PF06745.13 AIM19761.1 - 0.18 11.2 0.4 0.98 8.7 0.1 2.0 2 0 0 2 2 2 0 KaiC ATP-synt_ab PF00006.25 AIM19761.1 - 0.21 11.2 0.0 0.37 10.4 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain CBP_BcsG PF11658.8 AIM19762.1 - 5.4e-233 774.1 0.0 6.1e-233 773.9 0.0 1.0 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsG DltD PF04914.12 AIM19762.1 - 0.15 11.5 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 DltD protein CBP_BcsF PF11120.8 AIM19763.1 - 7.7e-23 80.4 0.3 1e-22 80.0 0.3 1.1 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsF CBP_GIL PF10995.8 AIM19764.1 - 1.7e-193 644.0 4.3 2.1e-193 643.7 4.3 1.0 1 0 0 1 1 1 1 Cellulose biosynthesis GIL CBP_BcsR PF10945.8 AIM19765.1 - 1e-21 76.1 0.8 1.2e-21 75.8 0.8 1.1 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsR CBP_BcsO PF17037.5 AIM19765.1 - 0.047 13.8 0.0 0.052 13.7 0.0 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsO CBP_BcsQ PF06564.12 AIM19766.1 - 3.4e-101 337.6 2.3 3.8e-101 337.5 2.3 1.0 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ CbiA PF01656.23 AIM19766.1 - 3.8e-06 27.0 0.0 8e-06 25.9 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 AIM19766.1 - 4.6e-06 26.7 0.0 0.0019 18.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain ArsA_ATPase PF02374.15 AIM19766.1 - 0.018 14.2 0.0 0.027 13.7 0.0 1.1 1 0 0 1 1 1 0 Anion-transporting ATPase MipZ PF09140.11 AIM19766.1 - 0.049 12.9 0.0 3.8 6.7 0.0 2.1 2 0 0 2 2 2 0 ATPase MipZ ParA PF10609.9 AIM19766.1 - 0.13 11.6 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Glycos_transf_2 PF00535.26 AIM19767.1 - 3.1e-34 118.2 0.0 4.9e-34 117.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AIM19767.1 - 8.1e-21 75.0 0.0 1.4e-20 74.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 AIM19767.1 - 5.9e-20 72.0 0.7 5.9e-20 72.0 0.7 3.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Cellulose_synt PF03552.14 AIM19767.1 - 1.6e-16 60.0 0.5 2.4e-11 42.9 0.1 3.1 1 1 2 3 3 3 3 Cellulose synthase Glyco_transf_21 PF13506.6 AIM19767.1 - 2e-14 53.5 0.0 4e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 PilZ PF07238.14 AIM19767.1 - 4.4e-10 39.8 0.0 7.7e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 PilZ domain BcsB PF03170.13 AIM19768.1 - 2.7e-222 739.4 4.3 3.2e-222 739.2 4.3 1.0 1 0 0 1 1 1 1 Bacterial cellulose synthase subunit Phage_holin_3_6 PF07332.11 AIM19768.1 - 0.055 13.5 0.6 0.14 12.2 0.6 1.7 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III End_N_terminal PF12218.8 AIM19768.1 - 0.14 11.8 0.0 2.4 7.9 0.0 2.5 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase Glyco_hydro_8 PF01270.17 AIM19769.1 - 1.8e-96 323.0 0.1 2.2e-96 322.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 8 BCSC_C PF05420.11 AIM19770.1 - 8e-122 406.6 10.6 1.2e-121 406.0 10.6 1.3 1 0 0 1 1 1 1 Cellulose synthase operon protein C C-terminus (BCSC_C) TPR_19 PF14559.6 AIM19770.1 - 1.4e-28 99.1 100.5 3.5e-08 33.8 2.7 11.5 8 4 4 12 12 12 7 Tetratricopeptide repeat TPR_16 PF13432.6 AIM19770.1 - 3.9e-14 53.0 99.0 5.7e-06 26.9 5.3 11.3 10 1 1 11 11 11 5 Tetratricopeptide repeat TPR_2 PF07719.17 AIM19770.1 - 6.5e-11 41.5 56.8 0.00039 20.3 0.5 12.2 13 0 0 13 13 12 6 Tetratricopeptide repeat TPR_7 PF13176.6 AIM19770.1 - 1.8e-09 36.9 34.2 5e-05 23.0 0.1 9.9 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_11 PF13414.6 AIM19770.1 - 2.2e-08 33.6 37.3 0.0034 17.0 0.3 9.0 8 1 1 9 9 9 3 TPR repeat TPR_12 PF13424.6 AIM19770.1 - 7.2e-08 32.6 65.2 2.4e-05 24.6 0.3 9.5 9 2 1 10 10 9 4 Tetratricopeptide repeat TPR_20 PF14561.6 AIM19770.1 - 3.1e-07 30.6 36.8 0.0063 16.8 0.0 8.1 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 AIM19770.1 - 4.9e-06 26.1 35.7 0.0098 15.7 0.2 9.0 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 AIM19770.1 - 9.7e-06 26.0 96.6 0.028 15.2 3.0 15.2 6 4 9 15 15 15 6 Tetratricopeptide repeat ANAPC3 PF12895.7 AIM19770.1 - 7.6e-05 22.9 14.8 0.041 14.1 2.4 5.5 5 0 0 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 AIM19770.1 - 9.6e-05 22.3 15.2 0.39 11.1 0.1 8.7 10 0 0 10 10 9 1 Tetratricopeptide repeat BTAD PF03704.17 AIM19770.1 - 0.00022 21.7 1.9 0.00022 21.7 1.9 6.6 6 2 1 7 7 5 1 Bacterial transcriptional activator domain TPR_17 PF13431.6 AIM19770.1 - 0.0021 18.3 0.1 0.0021 18.3 0.1 8.8 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_10 PF13374.6 AIM19770.1 - 0.0082 16.0 0.2 0.0082 16.0 0.2 10.1 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_15 PF13429.6 AIM19770.1 - 0.45 9.7 68.2 0.019 14.2 2.0 7.4 1 1 6 7 7 7 0 Tetratricopeptide repeat ETC_C1_NDUFA5 PF04716.14 AIM19770.1 - 2.4 8.0 4.7 1.1 9.2 0.1 2.9 3 0 0 3 3 3 0 ETC complex I subunit conserved region EAL PF00563.20 AIM19771.1 - 2.7e-63 213.7 0.1 5.8e-63 212.6 0.1 1.6 1 0 0 1 1 1 1 EAL domain GAPES3 PF17154.4 AIM19771.1 - 5e-58 194.4 2.4 1.6e-57 192.7 2.4 1.9 1 0 0 1 1 1 1 Gammaproteobacterial periplasmic sensor domain GGDEF PF00990.21 AIM19771.1 - 2.8e-20 72.7 0.0 1.1e-19 70.7 0.0 2.1 2 1 1 3 3 3 1 Diguanylate cyclase, GGDEF domain HAMP PF00672.25 AIM19771.1 - 1.1e-05 25.7 0.0 3.6e-05 24.0 0.0 2.0 1 0 0 1 1 1 1 HAMP domain SDF PF00375.18 AIM19772.1 - 1.9e-111 372.9 37.1 2.1e-111 372.7 37.1 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Peptidase_M16_C PF05193.21 AIM19773.1 - 7.4e-19 68.5 0.0 1.4e-18 67.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 AIM19773.1 - 2.1e-11 44.0 0.0 5.4e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Rotamase_3 PF13616.6 AIM19774.1 - 3.8e-23 82.3 0.0 4.2e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 AIM19774.1 - 2e-19 70.3 0.0 2.7e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 AIM19774.1 - 0.00017 22.5 0.0 0.00019 22.3 0.0 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain UvrD-helicase PF00580.21 AIM19775.1 - 1.5e-76 257.9 0.9 2.5e-75 253.9 0.9 2.3 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 AIM19775.1 - 1.1e-72 245.3 2.2 6.9e-72 242.7 0.0 2.6 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 AIM19775.1 - 2.8e-36 125.1 0.0 5.4e-36 124.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 AIM19775.1 - 1.2e-10 41.1 0.0 4.9e-10 39.1 0.0 2.0 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 AIM19775.1 - 3.7e-10 39.9 0.2 3e-05 23.8 0.1 2.4 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 AIM19775.1 - 1.6e-06 28.0 0.4 0.029 14.1 0.0 3.5 3 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.6 AIM19775.1 - 0.0092 15.6 0.0 2.4 7.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain S-AdoMet_synt_C PF02773.16 AIM19775.1 - 0.16 12.0 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 S-adenosylmethionine synthetase, C-terminal domain Ppx-GppA PF02541.16 AIM19776.1 - 6.4e-98 327.7 0.7 9.6e-98 327.1 0.1 1.5 2 0 0 2 2 2 1 Ppx/GppA phosphatase family DDR PF08841.10 AIM19776.1 - 0.02 13.9 0.0 0.042 12.8 0.0 1.5 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DEAD PF00270.29 AIM19777.1 - 4.9e-46 156.7 0.0 1.7e-44 151.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AIM19777.1 - 3.1e-30 104.8 0.0 1e-28 99.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 AIM19777.1 - 3.9e-06 27.0 0.0 6.4e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 AIM19777.1 - 0.0034 16.6 0.0 0.0057 15.9 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 AIM19777.1 - 0.03 14.6 0.1 0.089 13.1 0.1 1.8 1 1 0 1 1 1 0 AAA domain Thioredoxin PF00085.20 AIM19778.1 - 8.4e-34 115.7 0.0 9.2e-34 115.5 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 AIM19778.1 - 5.4e-09 36.5 0.0 1.1e-07 32.3 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 AIM19778.1 - 1.2e-06 28.8 0.0 0.0001 22.5 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.6 AIM19778.1 - 9.5e-05 22.2 0.0 0.0001 22.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 AIM19778.1 - 0.00058 19.8 0.0 0.00086 19.2 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family TraF PF13728.6 AIM19778.1 - 0.00091 19.1 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 AIM19778.1 - 0.0029 17.7 0.0 0.005 17.0 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 AIM19778.1 - 0.0034 17.1 0.0 0.03 14.0 0.0 1.9 1 1 1 2 2 2 1 Redoxin Thioredoxin_6 PF13848.6 AIM19778.1 - 0.0091 15.9 0.0 0.02 14.8 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 AIM19778.1 - 0.0097 15.9 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain HyaE PF07449.11 AIM19778.1 - 0.015 15.3 0.0 0.02 14.9 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE OST3_OST6 PF04756.13 AIM19778.1 - 0.036 13.4 0.0 0.047 13.1 0.0 1.3 1 1 0 1 1 1 0 OST3 / OST6 family, transporter family DUF836 PF05768.14 AIM19778.1 - 0.045 14.2 0.0 0.06 13.8 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) DSBA PF01323.20 AIM19778.1 - 0.086 12.6 0.0 0.68 9.7 0.0 1.9 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Rho_RNA_bind PF07497.12 AIM19779.1 - 2.6e-32 110.5 0.0 5.4e-32 109.5 0.0 1.6 1 0 0 1 1 1 1 Rho termination factor, RNA-binding domain ATP-synt_ab PF00006.25 AIM19779.1 - 2.1e-22 79.8 0.0 3e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Rho_N PF07498.12 AIM19779.1 - 2.4e-17 62.6 1.2 2.1e-16 59.6 0.2 2.7 3 0 0 3 3 3 1 Rho termination factor, N-terminal domain NACHT PF05729.12 AIM19779.1 - 1.4e-05 25.0 0.0 2.6e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 NACHT domain OB_RNB PF08206.11 AIM19779.1 - 0.0025 17.4 0.0 0.0051 16.5 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease B OB domain AAA_25 PF13481.6 AIM19779.1 - 0.0029 17.2 0.0 0.012 15.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 AIM19779.1 - 0.0038 17.6 0.0 0.0089 16.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AIM19779.1 - 0.0066 16.7 0.0 0.018 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain Shikimate_DH PF01488.20 AIM19779.1 - 0.078 13.0 0.4 5.9 7.0 0.1 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DnaB_C PF03796.15 AIM19779.1 - 0.097 12.0 0.1 0.28 10.5 0.0 1.8 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Terminase_GpA PF05876.12 AIM19779.1 - 0.11 11.0 0.0 7.5 5.0 0.0 2.1 2 0 0 2 2 2 0 Phage terminase large subunit (GpA) Glycos_transf_4 PF00953.21 AIM19780.1 - 5.5e-27 94.7 16.1 5.5e-27 94.7 16.1 2.4 3 0 0 3 3 3 1 Glycosyl transferase family 4 TMEM100 PF16311.5 AIM19780.1 - 0.1 12.2 0.0 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 Transmembrane protein 100 Wzz PF02706.15 AIM19781.1 - 1.1e-12 48.0 0.1 8.4e-12 45.2 0.0 2.3 2 0 0 2 2 2 1 Chain length determinant protein Alpha-L-AF_C PF06964.12 AIM19781.1 - 0.0081 16.3 0.2 0.013 15.7 0.2 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain DUF4893 PF16233.5 AIM19781.1 - 0.04 13.5 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4893) GNVR PF13807.6 AIM19781.1 - 0.73 9.8 3.1 1.7 8.6 0.0 2.6 3 0 0 3 3 3 0 G-rich domain on putative tyrosine kinase Epimerase_2 PF02350.19 AIM19782.1 - 6.9e-128 426.4 0.0 7.8e-128 426.2 0.0 1.0 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Glyco_transf_4 PF13439.6 AIM19782.1 - 0.033 14.2 0.0 0.083 12.9 0.0 1.7 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 AIM19782.1 - 0.07 12.7 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AIM19782.1 - 0.1 13.0 0.1 0.37 11.2 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 AIM19782.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase 4-like UDPG_MGDP_dh_N PF03721.14 AIM19783.1 - 1.1e-59 201.2 0.1 1.2e-58 197.8 0.0 2.0 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 AIM19783.1 - 2e-26 92.0 0.0 3.6e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 AIM19783.1 - 4.1e-20 72.2 0.0 1.1e-19 70.8 0.0 1.8 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_binding_2 PF03446.15 AIM19783.1 - 1e-08 35.5 0.5 3.6e-06 27.2 0.1 3.7 3 1 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 AIM19783.1 - 0.0018 17.7 0.2 0.21 10.9 0.0 2.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 AIM19783.1 - 0.0024 17.8 0.1 0.0072 16.2 0.1 1.8 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 AIM19783.1 - 0.0029 17.9 0.2 0.02 15.1 0.0 2.3 2 0 0 2 2 2 1 TrkA-N domain ApbA PF02558.16 AIM19783.1 - 0.0083 15.8 0.3 0.33 10.6 0.1 3.1 3 1 0 3 3 3 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 AIM19783.1 - 0.018 15.0 0.3 4.2 7.3 0.0 2.6 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Semialdhyde_dh PF01118.24 AIM19783.1 - 0.032 14.6 0.2 0.23 11.9 0.0 2.5 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 AIM19783.1 - 0.063 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 AIM19783.1 - 0.16 12.5 0.9 7.2 7.3 0.1 3.4 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent GDP_Man_Dehyd PF16363.5 AIM19784.1 - 8.9e-99 331.0 0.0 1e-98 330.8 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 AIM19784.1 - 3.6e-73 246.0 0.1 4.4e-73 245.7 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 AIM19784.1 - 3.8e-15 55.8 0.0 5.8e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 AIM19784.1 - 1.9e-14 53.4 0.1 3.2e-14 52.7 0.1 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 AIM19784.1 - 4.7e-14 52.1 0.0 7.8e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 AIM19784.1 - 1.5e-12 47.2 0.0 2.6e-09 36.6 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein adh_short PF00106.25 AIM19784.1 - 1.7e-05 24.4 0.5 0.0054 16.2 0.1 2.4 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 AIM19784.1 - 0.012 15.5 0.1 0.023 14.6 0.1 1.4 1 0 0 1 1 1 0 KR domain Sacchrp_dh_NADP PF03435.18 AIM19784.1 - 0.012 15.8 0.1 0.021 15.1 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NTP_transferase PF00483.23 AIM19785.1 - 2.8e-69 233.5 0.0 3.3e-69 233.2 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AIM19785.1 - 1.4e-09 38.5 0.0 1.9e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 AIM19785.1 - 0.0024 17.7 0.0 0.0035 17.1 0.0 1.2 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP_transf_3 PF02348.19 AIM19785.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase Acetyltransf_1 PF00583.25 AIM19786.1 - 1.1e-12 48.2 0.0 1.6e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AIM19786.1 - 6.5e-09 35.8 0.0 9.6e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AIM19786.1 - 3.1e-07 31.1 0.0 5e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AIM19786.1 - 4.4e-07 30.2 0.1 8.1e-07 29.4 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AIM19786.1 - 0.00068 19.7 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 AIM19786.1 - 0.0028 17.6 0.1 0.0058 16.6 0.1 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 AIM19786.1 - 0.01 15.5 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AIM19786.1 - 0.018 15.1 0.1 0.074 13.1 0.1 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain CBS PF00571.28 AIM19786.1 - 0.15 12.5 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 CBS domain DegT_DnrJ_EryC1 PF01041.17 AIM19787.1 - 3.6e-88 296.3 0.0 4.3e-88 296.0 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 AIM19787.1 - 3.8e-11 42.8 0.1 8.5e-11 41.6 0.1 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 AIM19787.1 - 5.2e-08 32.2 0.0 8.8e-08 31.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 AIM19787.1 - 0.0002 20.8 0.1 0.00037 19.9 0.1 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.20 AIM19787.1 - 0.0014 17.4 0.0 0.0034 16.2 0.0 1.6 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Cys_Met_Meta_PP PF01053.20 AIM19787.1 - 0.01 14.4 0.2 0.015 13.8 0.2 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Polysacc_synt PF01943.17 AIM19788.1 - 2e-10 40.5 17.3 2e-10 40.5 17.3 1.9 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein Polysacc_synt_3 PF13440.6 AIM19788.1 - 3.3e-07 29.8 8.4 5.7e-07 29.1 8.4 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Glyco_transf_56 PF07429.11 AIM19789.1 - 4.1e-182 605.2 0.2 4.6e-182 605.0 0.2 1.0 1 0 0 1 1 1 1 4-alpha-L-fucosyltransferase glycosyl transferase group 56 WzyE PF06899.11 AIM19790.1 - 5e-260 862.9 49.9 5.9e-260 862.6 49.9 1.0 1 0 0 1 1 1 1 WzyE protein, O-antigen assembly polymerase Glyco_tran_WecB PF03808.13 AIM19791.1 - 1.4e-52 178.0 0.2 1.8e-52 177.7 0.2 1.1 1 0 0 1 1 1 1 Glycosyl transferase WecB/TagA/CpsF family AA_permease PF00324.21 AIM19792.1 - 2.8e-104 349.4 49.9 3.3e-104 349.1 49.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 AIM19792.1 - 3.6e-40 138.1 56.4 4.9e-40 137.7 56.4 1.0 1 0 0 1 1 1 1 Amino acid permease HemY_N PF07219.13 AIM19793.1 - 1.7e-35 121.4 2.2 1.7e-35 121.4 2.2 4.2 5 1 0 5 5 3 2 HemY protein N-terminus TPR_2 PF07719.17 AIM19793.1 - 1.2e-05 25.1 0.1 1.2e-05 25.1 0.1 4.4 4 1 1 5 5 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 AIM19793.1 - 1.8e-05 25.2 22.8 0.0063 17.0 1.7 4.9 3 1 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 AIM19793.1 - 5.3e-05 22.9 0.1 0.00064 19.4 0.0 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 AIM19793.1 - 0.00016 22.2 2.2 0.00016 22.2 2.2 3.3 3 1 0 3 3 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 AIM19793.1 - 0.0078 17.0 1.1 0.0078 17.0 1.1 6.7 2 2 6 8 8 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 AIM19793.1 - 0.015 15.5 5.3 0.35 11.1 0.3 3.3 2 1 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TRAPPC9-Trs120 PF08626.11 AIM19793.1 - 0.016 12.6 0.2 0.018 12.4 0.2 1.1 1 0 0 1 1 1 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_11 PF13414.6 AIM19793.1 - 0.024 14.3 0.1 0.068 12.9 0.1 1.8 1 0 0 1 1 1 0 TPR repeat DUF4834 PF16118.5 AIM19793.1 - 0.045 14.7 2.5 0.082 13.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) TPR_6 PF13174.6 AIM19793.1 - 0.046 14.4 4.0 0.1 13.2 0.1 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 AIM19793.1 - 0.074 13.2 0.4 0.074 13.2 0.4 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat Transcrip_reg PF01709.20 AIM19793.1 - 0.14 11.6 0.1 0.44 9.9 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator Ferric_reduct PF01794.19 AIM19793.1 - 0.14 12.3 1.0 0.26 11.4 1.0 1.4 1 0 0 1 1 1 0 Ferric reductase like transmembrane component Mem_trans PF03547.18 AIM19793.1 - 0.16 10.3 0.4 0.22 9.9 0.4 1.1 1 0 0 1 1 1 0 Membrane transport protein TPR_7 PF13176.6 AIM19793.1 - 0.2 11.7 7.3 0.45 10.6 0.2 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 AIM19793.1 - 0.24 11.7 1.0 28 5.2 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat TrbC PF04956.13 AIM19793.1 - 0.26 11.5 2.1 0.48 10.7 2.1 1.4 1 0 0 1 1 1 0 TrbC/VIRB2 family Claudin_3 PF06653.11 AIM19793.1 - 1.5 8.8 3.5 2.1 8.3 3.5 1.2 1 0 0 1 1 1 0 Tight junction protein, Claudin-like PsbY PF06298.11 AIM19793.1 - 2.8 7.9 7.2 0.45 10.5 0.2 2.8 2 0 0 2 2 2 0 Photosystem II protein Y (PsbY) OppC_N PF12911.7 AIM19793.1 - 3.9 7.5 7.6 16 5.6 0.3 2.6 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C HemX PF04375.14 AIM19794.1 - 1.4e-136 455.2 22.0 1.7e-136 455.0 22.0 1.0 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase RskA PF10099.9 AIM19794.1 - 0.0073 16.6 11.8 0.011 16.1 10.7 1.8 1 1 0 1 1 1 1 Anti-sigma-K factor rskA DUF4618 PF15397.6 AIM19794.1 - 0.0077 15.7 4.9 1.3 8.4 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4618) Tweety PF04906.13 AIM19794.1 - 0.026 13.2 0.3 0.05 12.3 0.3 1.4 1 0 0 1 1 1 0 Tweety Spc7 PF08317.11 AIM19794.1 - 0.036 12.9 5.5 0.09 11.6 5.5 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein VIT1 PF01988.19 AIM19794.1 - 0.039 13.8 0.2 0.067 13.0 0.2 1.4 1 0 0 1 1 1 0 VIT family DUF1043 PF06295.12 AIM19794.1 - 0.041 13.9 5.9 0.026 14.5 3.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DUF4366 PF14283.6 AIM19794.1 - 0.055 13.5 0.1 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF1664 PF07889.12 AIM19794.1 - 0.2 11.7 8.6 0.27 11.3 6.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2570 PF10828.8 AIM19794.1 - 0.39 10.6 8.2 0.29 11.0 4.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) Hemagglutinin PF00509.18 AIM19794.1 - 1.4 7.3 3.8 0.91 7.8 0.5 1.9 1 1 0 2 2 2 0 Haemagglutinin Phage_Mu_Gam PF07352.12 AIM19794.1 - 2.4 8.1 6.1 3.1 7.7 5.1 1.7 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein PRKG1_interact PF15898.5 AIM19794.1 - 3.9 8.4 11.1 0.56 11.1 5.7 2.3 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain HEM4 PF02602.15 AIM19795.1 - 1.6e-40 138.9 0.0 1.8e-40 138.7 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Oxidored_nitro PF00148.19 AIM19795.1 - 0.23 10.2 0.0 0.25 10.0 0.0 1.1 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Porphobil_deam PF01379.20 AIM19796.1 - 2.1e-82 275.6 0.0 2.7e-82 275.2 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 AIM19796.1 - 1.3e-22 80.0 0.1 2.4e-22 79.1 0.1 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Adenylate_cycl PF01295.18 AIM19797.1 - 3.6e-257 854.8 0.0 4.3e-257 854.6 0.0 1.0 1 0 0 1 1 1 1 Adenylate cyclase, class-I Adenyl_cycl_N PF12633.7 AIM19797.1 - 2e-82 275.9 0.0 7.1e-81 270.9 0.0 2.2 2 0 0 2 2 2 1 Adenylate cyclase NT domain Frataxin_Cyay PF01491.16 AIM19798.1 - 1.4e-29 102.3 0.0 1.6e-29 102.1 0.0 1.0 1 0 0 1 1 1 1 Frataxin-like domain DUF1521 PF07481.11 AIM19798.1 - 0.047 13.7 0.1 0.066 13.2 0.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1521) LPAM_2 PF13627.6 AIM19799.1 - 3.6e-09 36.2 5.2 5.8e-09 35.5 5.2 1.4 1 0 0 1 1 1 1 Prokaryotic lipoprotein-attachment site DAP_epimerase PF01678.19 AIM19800.1 - 7.5e-68 226.2 0.3 5.4e-34 117.0 0.0 2.0 2 0 0 2 2 2 2 Diaminopimelate epimerase DUF484 PF04340.12 AIM19801.1 - 5.5e-74 248.6 1.1 6.8e-74 248.3 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF484 ABC_tran_CTD PF16326.5 AIM19801.1 - 0.08 13.2 3.4 0.21 11.9 1.5 2.4 2 0 0 2 2 2 0 ABC transporter C-terminal domain Phage_integrase PF00589.22 AIM19802.1 - 1.8e-51 174.3 0.1 3.4e-51 173.5 0.0 1.5 2 0 0 2 2 2 1 Phage integrase family Phage_int_SAM_1 PF02899.17 AIM19802.1 - 2e-20 72.9 2.1 2e-20 72.9 2.1 1.9 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain PaaA_PaaC PF05138.12 AIM19802.1 - 0.03 13.5 0.1 0.07 12.3 0.1 1.6 1 0 0 1 1 1 0 Phenylacetic acid catabolic protein Phage_int_SAM_5 PF13102.6 AIM19802.1 - 0.047 14.0 0.0 3.7 8.0 0.0 2.4 1 1 1 2 2 2 0 Phage integrase SAM-like domain Phage_int_SAM_4 PF13495.6 AIM19802.1 - 0.058 13.9 0.2 0.93 10.0 0.0 2.2 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Hydrolase PF00702.26 AIM19803.1 - 2.3e-17 64.0 0.0 2.8e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 AIM19803.1 - 9.2e-16 58.4 0.0 9.2e-15 55.2 0.0 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AIM19803.1 - 9.9e-11 41.5 0.0 2.6e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like PGP_phosphatase PF09419.10 AIM19803.1 - 0.037 13.7 0.1 0.5 10.0 0.0 2.6 4 0 0 4 4 4 0 Mitochondrial PGP phosphatase UvrD-helicase PF00580.21 AIM19804.1 - 4.3e-77 259.7 0.0 1.3e-76 258.1 0.0 1.8 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 AIM19804.1 - 1e-76 258.6 0.0 4.7e-76 256.4 0.0 1.9 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 AIM19804.1 - 2e-32 112.6 0.0 7e-32 110.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 AIM19804.1 - 7.8e-10 38.4 0.0 1.7e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 AIM19804.1 - 4.6e-09 36.3 0.0 0.00058 19.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain Exonuc_V_gamma PF04257.14 AIM19804.1 - 0.00037 18.9 1.3 0.00098 17.5 0.2 1.9 2 0 0 2 2 2 1 Exodeoxyribonuclease V, gamma subunit Viral_helicase1 PF01443.18 AIM19804.1 - 0.004 16.9 0.0 4.4 7.0 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 AIM19804.1 - 0.027 13.9 0.0 0.38 10.2 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein DUF3553 PF12073.8 AIM19804.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3553) Cupin_2 PF07883.11 AIM19805.1 - 0.00068 19.3 0.0 0.0017 18.0 0.0 1.7 1 1 0 1 1 1 1 Cupin domain FdtA PF05523.11 AIM19805.1 - 0.19 11.5 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 WxcM-like, C-terminal CorA PF01544.18 AIM19806.1 - 1.9e-54 185.0 0.4 2.2e-54 184.8 0.4 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein CheY-binding PF09078.11 AIM19806.1 - 0.0099 16.0 0.5 1.2 9.3 0.4 2.5 2 0 0 2 2 2 1 CheY binding JMY PF15871.5 AIM19806.1 - 0.057 12.7 3.5 0.076 12.3 2.6 1.6 1 1 1 2 2 2 0 Junction-mediating and -regulatory protein TPR_14 PF13428.6 AIM19806.1 - 0.16 12.9 0.8 2.9 9.0 0.1 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat EamA PF00892.20 AIM19807.1 - 2e-21 76.6 36.1 1.1e-16 61.3 11.2 2.0 2 0 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 AIM19807.1 - 0.025 13.8 3.1 0.039 13.1 2.1 1.8 1 1 1 2 2 2 0 Nucleotide-sugar transporter Multi_Drug_Res PF00893.19 AIM19807.1 - 2.5 8.9 12.0 0.94 10.2 0.9 3.6 3 2 0 3 3 3 0 Small Multidrug Resistance protein 4HBT PF03061.22 AIM19808.1 - 1.7e-17 63.5 0.3 2.4e-17 63.0 0.3 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 AIM19808.1 - 1.9e-06 28.3 0.4 2.7e-06 27.8 0.4 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily AphA_like PF14557.6 AIM19808.1 - 0.073 12.8 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Putative AphA-like transcriptional regulator RQC PF09382.10 AIM19809.1 - 8.9e-40 135.0 0.0 2.4e-39 133.6 0.0 1.8 1 0 0 1 1 1 1 RQC domain HRDC PF00570.23 AIM19809.1 - 4.1e-24 84.3 0.1 1.1e-23 83.0 0.0 1.8 2 0 0 2 2 2 1 HRDC domain Helicase_C PF00271.31 AIM19809.1 - 4.1e-23 81.8 0.0 2.9e-19 69.4 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 AIM19809.1 - 7.7e-21 74.6 0.0 6.4e-20 71.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 AIM19809.1 - 5.3e-16 59.1 0.4 1.3e-15 57.8 0.4 1.8 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 AIM19809.1 - 0.0065 16.5 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-CXXC PF02008.20 AIM19809.1 - 0.012 15.6 0.7 0.028 14.4 0.7 1.6 1 0 0 1 1 1 0 CXXC zinc finger domain Peptidase_S66 PF02016.15 AIM19809.1 - 0.17 12.0 0.1 1.8 8.7 0.0 2.3 2 0 0 2 2 2 0 LD-carboxypeptidase N-terminal domain LysE PF01810.18 AIM19810.1 - 8.8e-53 178.6 15.3 1e-52 178.4 15.3 1.0 1 0 0 1 1 1 1 LysE type translocator TerC PF03741.16 AIM19810.1 - 1.3e-05 24.9 5.2 1.3e-05 24.9 5.2 1.9 2 1 0 2 2 2 1 Integral membrane protein TerC family DUF808 PF05661.12 AIM19810.1 - 0.04 13.0 0.3 0.069 12.2 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF808) LysE PF01810.18 AIM19811.1 - 5.8e-43 146.6 12.5 6.5e-43 146.4 12.5 1.0 1 0 0 1 1 1 1 LysE type translocator Hydrolase_4 PF12146.8 AIM19812.1 - 8e-53 179.1 0.0 1e-52 178.8 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AIM19812.1 - 9.4e-23 81.2 0.1 1.3e-22 80.7 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AIM19812.1 - 6.3e-09 36.7 6.0 1e-08 36.1 6.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 AIM19812.1 - 1.5e-05 24.6 0.0 0.0039 16.7 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_3 PF08282.12 AIM19813.1 - 4.7e-63 213.3 0.0 5.3e-63 213.1 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 AIM19813.1 - 4.2e-14 52.7 0.0 2.6e-06 27.1 0.0 2.1 1 1 1 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 AIM19813.1 - 2.8e-07 31.0 0.1 0.001 19.4 0.0 2.9 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 AIM19813.1 - 8.2e-05 23.1 0.6 0.015 15.7 0.0 3.0 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AIM19813.1 - 0.00014 21.9 0.0 0.00041 20.4 0.0 1.9 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase GDPD PF03009.17 AIM19814.1 - 6.7e-74 248.9 0.1 7.6e-74 248.7 0.1 1.0 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family CRISPR_Cas2 PF09827.9 AIM19814.1 - 0.036 14.3 0.0 0.074 13.2 0.0 1.5 1 0 0 1 1 1 0 CRISPR associated protein Cas2 MFS_1 PF07690.16 AIM19815.1 - 1.2e-46 159.3 33.1 2.7e-44 151.5 27.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2070 PF09843.9 AIM19815.1 - 5.2 5.2 9.7 0.17 10.1 3.0 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) DAO PF01266.24 AIM19816.1 - 7.2e-54 183.7 3.1 7.2e-54 183.7 3.1 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AIM19816.1 - 3.2e-10 39.7 6.2 4.4e-09 35.9 6.2 2.1 1 1 0 1 1 1 1 FAD binding domain Fer2_BFD PF04324.15 AIM19816.1 - 2.4e-09 37.4 3.1 5.7e-09 36.2 3.1 1.7 1 0 0 1 1 1 1 BFD-like [2Fe-2S] binding domain FAD_binding_3 PF01494.19 AIM19816.1 - 8.5e-09 35.1 2.0 4.9e-08 32.6 2.0 2.0 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 AIM19816.1 - 1.5e-08 34.5 1.5 8.3e-08 32.0 1.5 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 AIM19816.1 - 0.00013 21.9 0.1 0.00024 21.0 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase Thi4 PF01946.17 AIM19816.1 - 0.00046 19.5 0.3 0.0019 17.5 0.2 1.9 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 AIM19816.1 - 0.00091 19.4 1.3 0.0026 17.9 1.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AIM19816.1 - 0.0023 17.2 0.1 0.0044 16.3 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AIM19816.1 - 0.014 14.1 0.4 0.024 13.4 0.4 1.3 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.18 AIM19816.1 - 0.026 14.4 0.1 0.051 13.5 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 AIM19816.1 - 0.061 13.9 0.4 2.5 8.7 0.3 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AIM19816.1 - 0.09 12.0 1.0 0.15 11.3 1.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AIM19816.1 - 0.093 11.8 0.4 0.13 11.3 0.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A K_oxygenase PF13434.6 AIM19816.1 - 0.14 11.2 0.2 5.6 6.0 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 AIM19817.1 - 1e-65 222.5 0.0 1.2e-65 222.3 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 AIM19817.1 - 6.2e-12 45.8 0.5 1.2e-10 41.5 0.5 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 AIM19817.1 - 1.7e-08 34.1 0.1 7.2e-05 22.2 0.2 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AIM19817.1 - 6.8e-06 25.0 0.1 0.00017 20.4 0.8 2.0 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 AIM19817.1 - 8.1e-06 25.2 0.2 0.00019 20.6 0.3 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 AIM19817.1 - 0.00031 20.2 3.9 0.00045 19.7 3.9 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 AIM19817.1 - 0.00052 19.4 0.3 0.00088 18.6 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 AIM19817.1 - 0.00081 19.6 1.2 0.0019 18.4 1.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 AIM19817.1 - 0.00097 18.3 0.9 0.0036 16.4 0.4 2.1 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox PF00070.27 AIM19817.1 - 0.0038 17.8 0.1 0.022 15.3 0.4 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 AIM19817.1 - 0.025 13.8 0.5 0.038 13.2 0.5 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 AIM19817.1 - 0.053 12.8 0.4 0.18 11.1 0.5 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CCG PF02754.16 AIM19818.1 - 1.2e-30 105.6 0.5 5.6e-14 52.1 0.1 2.5 2 0 0 2 2 2 2 Cysteine-rich domain Fer4_8 PF13183.6 AIM19818.1 - 7.2e-10 39.2 5.3 7.2e-10 39.2 5.3 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AIM19818.1 - 2.2e-06 27.7 12.9 0.0015 18.6 0.7 3.3 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4 PF00037.27 AIM19818.1 - 7.2e-06 25.6 11.7 0.0073 16.1 2.3 2.8 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 AIM19818.1 - 1.3e-05 25.7 11.7 2.5e-05 24.7 9.7 2.6 2 1 1 3 3 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 AIM19818.1 - 1.8e-05 25.2 10.1 1.8e-05 25.2 10.1 2.4 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 AIM19818.1 - 1.9e-05 24.7 13.1 0.0011 19.1 1.4 3.1 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 AIM19818.1 - 0.00019 21.7 16.7 0.0087 16.5 2.1 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_18 PF13746.6 AIM19818.1 - 0.0025 18.0 3.5 0.67 10.2 0.0 2.6 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AIM19818.1 - 0.0068 16.4 18.0 0.098 12.8 2.3 3.4 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_16 PF13484.6 AIM19818.1 - 0.025 15.5 14.8 0.079 13.9 0.6 2.8 3 0 0 3 3 2 0 4Fe-4S double cluster binding domain Fer4_22 PF17179.4 AIM19818.1 - 0.28 12.1 10.7 0.5 11.2 0.2 3.0 2 1 1 3 3 2 0 4Fe-4S dicluster domain Fer4_6 PF12837.7 AIM19818.1 - 0.3 11.2 21.7 0.12 12.5 3.7 2.8 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_20 PF14691.6 AIM19818.1 - 0.77 9.5 8.1 0.47 10.2 0.2 2.8 3 0 0 3 3 3 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_21 PF14697.6 AIM19818.1 - 0.88 9.8 18.3 1 9.5 4.4 2.9 2 1 0 2 2 1 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 AIM19818.1 - 1.1 10.3 17.3 0.59 11.2 4.7 2.9 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.10 AIM19818.1 - 7.1 6.9 6.5 39 4.5 0.2 2.7 2 0 0 2 2 2 0 c-SKI Smad4 binding domain DcrB PF08786.11 AIM19819.1 - 1.6e-25 89.7 0.2 2.1e-25 89.3 0.2 1.1 1 0 0 1 1 1 1 DcrB Acetyltransf_6 PF13480.7 AIM19820.1 - 1.7e-08 34.8 1.0 2.9e-08 34.0 0.3 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AIM19820.1 - 2.8e-08 34.0 0.1 3.6e-08 33.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AIM19820.1 - 3.5e-05 23.7 0.0 4.6e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AIM19820.1 - 0.00011 22.5 0.0 0.0002 21.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AIM19820.1 - 0.044 13.9 0.0 0.075 13.2 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Vut_1 PF02592.15 AIM19821.1 - 1.4e-34 119.6 15.7 1.4e-34 119.6 15.7 1.6 2 0 0 2 2 2 1 Putative vitamin uptake transporter DUF373 PF04123.13 AIM19821.1 - 5 6.5 8.0 8.8 5.7 8.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF373) TusA PF01206.17 AIM19822.1 - 1.2e-24 85.9 0.0 1.3e-24 85.8 0.0 1.0 1 0 0 1 1 1 1 Sulfurtransferase TusA DUF2249 PF10006.9 AIM19822.1 - 0.00099 18.9 0.1 0.0011 18.8 0.1 1.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2249) Imm58 PF15581.6 AIM19823.1 - 0.064 13.4 0.0 0.066 13.3 0.0 1.1 1 0 0 1 1 1 0 Immunity protein 58 ParE_toxin PF05016.15 AIM19824.1 - 1.1e-17 64.4 1.1 1.2e-17 64.3 1.1 1.0 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE YafQ_toxin PF15738.5 AIM19824.1 - 0.048 14.0 0.2 0.25 11.7 0.2 1.9 1 1 0 1 1 1 0 Bacterial toxin of type II toxin-antitoxin system, YafQ E1-E2_ATPase PF00122.20 AIM19825.1 - 2.3e-47 160.9 0.4 7.9e-47 159.1 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 AIM19825.1 - 4.3e-37 128.5 3.8 7.7e-37 127.6 3.8 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 AIM19825.1 - 1.3e-11 44.7 0.0 3e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 AIM19825.1 - 5.2e-09 36.2 1.1 8.9e-07 28.9 1.2 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Spore_YhcN_YlaJ PF09580.10 AIM19825.1 - 0.0031 17.6 0.0 0.29 11.2 0.0 2.4 2 0 0 2 2 2 1 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) HAD PF12710.7 AIM19825.1 - 0.11 12.9 0.0 0.53 10.7 0.0 2.2 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Peptidase_M10_C PF08548.11 AIM19826.1 - 7.6e-83 277.2 15.1 7.6e-83 277.2 15.1 2.0 2 1 0 2 2 2 1 Peptidase M10 serralysin C terminal HemolysinCabind PF00353.19 AIM19826.1 - 5.2e-23 80.6 44.5 2.5e-10 40.2 11.3 4.0 3 1 2 5 5 5 3 RTX calcium-binding nonapeptide repeat (4 copies) Peptidase_M10 PF00413.24 AIM19826.1 - 7e-10 39.0 0.3 6.4e-09 35.8 0.1 2.3 2 0 0 2 2 2 1 Matrixin Reprolysin_4 PF13583.6 AIM19826.1 - 1.3e-06 28.2 0.4 2.7e-06 27.2 0.4 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 AIM19826.1 - 3.3e-06 27.4 0.2 8.1e-06 26.1 0.2 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 AIM19826.1 - 5.1e-05 23.8 0.3 0.00017 22.1 0.1 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 AIM19826.1 - 0.0085 16.0 0.3 0.022 14.7 0.3 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M43 PF05572.13 AIM19826.1 - 0.018 15.0 0.1 0.04 13.8 0.1 1.6 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Astacin PF01400.24 AIM19826.1 - 0.13 11.8 0.4 2.5 7.6 0.1 2.3 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Inh PF02974.14 AIM19827.1 - 5.4e-17 61.7 0.0 6.6e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 Protease inhibitor Inh Rbx_binding PF18113.1 AIM19827.1 - 0.015 15.1 0.1 0.032 14.0 0.0 1.6 2 0 0 2 2 2 0 Rubredoxin binding C-terminal domain YhhN PF07947.14 AIM19828.1 - 2.3e-40 138.2 24.5 2.7e-40 137.9 24.5 1.1 1 0 0 1 1 1 1 YhhN family DUF2500 PF10694.9 AIM19829.1 - 7.4e-30 103.7 0.0 8.2e-30 103.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2500) Nrap_D2 PF17403.2 AIM19829.1 - 0.007 16.1 0.0 0.061 13.1 0.0 1.9 1 1 1 2 2 2 1 Nrap protein PAP/OAS-like domain Cadherin_C_2 PF16492.5 AIM19829.1 - 0.12 13.1 0.0 0.24 12.1 0.0 1.5 1 1 1 2 2 2 0 Cadherin cytoplasmic C-terminal DUF1145 PF06611.12 AIM19830.1 - 1.7e-28 98.3 5.4 2.6e-28 97.8 5.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1145) Cons_hypoth95 PF03602.15 AIM19831.1 - 5.3e-60 202.2 0.0 6.1e-60 202.0 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 AIM19831.1 - 6.5e-05 22.5 0.0 9e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain MethyltransfD12 PF02086.15 AIM19831.1 - 0.22 11.2 0.0 6.6 6.3 0.0 2.1 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase SRP54 PF00448.22 AIM19832.1 - 3.5e-78 261.7 2.1 6.4e-78 260.9 2.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 AIM19832.1 - 2e-13 50.4 0.7 4.3e-13 49.3 0.3 1.8 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain Zeta_toxin PF06414.12 AIM19832.1 - 5.3e-08 32.4 0.1 9.4e-08 31.6 0.1 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_30 PF13604.6 AIM19832.1 - 8.4e-05 22.4 1.7 8.4e-05 22.4 1.7 1.7 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.6 AIM19832.1 - 9.4e-05 22.7 0.1 0.00033 20.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AIM19832.1 - 0.00037 20.7 0.1 0.0007 19.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 AIM19832.1 - 0.00037 20.9 0.1 0.00095 19.6 0.1 1.7 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 AIM19832.1 - 0.00061 18.8 0.7 0.0045 16.0 0.7 2.0 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 AIM19832.1 - 0.00083 19.1 0.1 0.082 12.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AIM19832.1 - 0.00095 19.6 0.1 0.00095 19.6 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 AIM19832.1 - 0.00097 19.7 0.0 0.0024 18.4 0.0 1.7 1 1 0 1 1 1 1 ABC transporter APS_kinase PF01583.20 AIM19832.1 - 0.0028 17.6 0.0 0.0065 16.4 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase CbiA PF01656.23 AIM19832.1 - 0.0043 17.1 0.7 0.041 13.9 0.7 2.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA PF00004.29 AIM19832.1 - 0.0088 16.5 0.1 0.019 15.4 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.17 AIM19832.1 - 0.013 15.2 0.4 0.067 12.9 0.1 2.2 2 0 0 2 2 2 0 Thymidylate kinase AAA_31 PF13614.6 AIM19832.1 - 0.038 13.9 0.1 0.067 13.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 AIM19832.1 - 0.039 14.0 0.4 0.38 10.9 0.3 2.5 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.6 AIM19832.1 - 0.043 13.9 0.0 0.078 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 AIM19832.1 - 0.048 12.9 0.1 0.069 12.4 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 AIM19832.1 - 0.093 12.7 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 AIM19832.1 - 0.14 12.1 0.7 0.85 9.5 0.1 2.1 2 0 0 2 2 2 0 NTPase Trypan_PARP PF05887.11 AIM19832.1 - 2.4 8.2 95.1 0.33 10.9 41.8 3.7 1 1 2 3 3 2 0 Procyclic acidic repetitive protein (PARP) ABC_tran PF00005.27 AIM19833.1 - 5.8e-36 124.0 0.0 9.2e-36 123.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIM19833.1 - 3.9e-06 26.9 0.0 0.011 15.6 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AIM19833.1 - 4.4e-05 23.1 0.0 9.2e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AIM19833.1 - 0.0004 20.3 0.0 0.00086 19.2 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 AIM19833.1 - 0.00094 19.6 0.0 0.0013 19.2 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 AIM19833.1 - 0.011 16.3 0.0 0.016 15.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AIM19833.1 - 0.02 14.5 0.0 0.36 10.4 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 AIM19833.1 - 0.038 14.3 0.1 0.1 12.9 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 AIM19833.1 - 0.066 12.9 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 AIM19833.1 - 0.08 13.0 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 AIM19833.1 - 0.11 12.4 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_33 PF13671.6 AIM19833.1 - 0.13 12.4 0.2 0.44 10.7 0.1 1.8 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 AIM19833.1 - 0.2 11.0 0.0 14 5.1 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain FtsX_ECD PF18075.1 AIM19834.1 - 1.2e-14 54.7 0.0 1.7e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 FtsX extracellular domain FtsX PF02687.21 AIM19834.1 - 7e-05 23.2 6.3 7e-05 23.2 6.3 3.0 3 0 0 3 3 3 1 FtsX-like permease family DUF1418 PF07214.12 AIM19834.1 - 0.0045 16.8 5.6 0.48 10.3 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF1418) SieB PF14163.6 AIM19834.1 - 0.085 12.3 0.6 1.6 8.2 0.0 2.4 2 0 0 2 2 2 0 Super-infection exclusion protein B Sigma70_r4 PF04545.16 AIM19835.1 - 2.6e-17 62.1 0.3 8.6e-16 57.2 0.1 2.5 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 AIM19835.1 - 1.5e-16 59.9 0.0 3e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r1_2 PF00140.20 AIM19835.1 - 1.4e-07 31.4 0.9 4.5e-07 29.8 0.9 1.9 1 0 0 1 1 1 1 Sigma-70 factor, region 1.2 KORA PF16509.5 AIM19835.1 - 0.00057 20.1 0.1 0.57 10.5 0.1 2.5 2 0 0 2 2 2 2 TrfB plasmid transcriptional repressor HTH_10 PF04967.12 AIM19835.1 - 0.017 14.9 0.0 0.18 11.7 0.0 2.5 2 0 0 2 2 2 0 HTH DNA binding domain UCR_14kD PF02271.16 AIM19835.1 - 0.03 14.3 0.1 0.31 11.0 0.1 2.5 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit GerE PF00196.19 AIM19835.1 - 0.11 12.1 0.4 0.64 9.6 0.1 2.3 3 0 0 3 3 3 0 Bacterial regulatory proteins, luxR family DUF5412 PF17428.2 AIM19835.1 - 0.13 12.1 0.1 0.25 11.2 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5412) HTH_AsnC-type PF13404.6 AIM19835.1 - 0.15 11.9 1.0 1.2 9.0 0.1 2.7 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain IF2_N PF04760.15 AIM19835.1 - 0.21 11.4 1.7 16 5.4 0.0 3.2 4 0 0 4 4 4 0 Translation initiation factor IF-2, N-terminal region Sigma70_r3 PF04539.16 AIM19835.1 - 0.35 11.0 3.6 8.7 6.5 0.0 2.9 3 0 0 3 3 3 0 Sigma-70 region 3 TPR_16 PF13432.6 AIM19836.1 - 1.5 9.5 57.0 0.048 14.3 9.8 6.9 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 AIM19836.1 - 5.1 7.5 31.5 0.62 10.3 0.4 8.3 8 1 0 8 8 8 0 Tetratricopeptide repeat DUF3142 PF11340.8 AIM19837.1 - 1.7e-100 335.5 4.8 2.5e-100 334.9 4.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3142) CobW_C PF07683.14 AIM19837.1 - 1.7 8.6 4.5 2.5 8.1 0.1 2.9 2 1 0 2 2 2 0 Cobalamin synthesis protein cobW C-terminal domain PanZ PF12568.8 AIM19838.1 - 1.8e-51 173.2 0.1 2e-51 173.0 0.1 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_1 PF00583.25 AIM19838.1 - 4.7e-06 26.8 0.0 5.1e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AIM19838.1 - 9.8e-06 25.5 0.0 1e-05 25.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AIM19838.1 - 0.026 14.5 0.1 0.035 14.1 0.1 1.2 1 0 0 1 1 1 0 FR47-like protein Peripla_BP_6 PF13458.6 AIM19839.1 - 6.9e-60 203.5 3.2 8e-60 203.3 3.2 1.0 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 AIM19839.1 - 5.6e-23 81.6 0.0 1.2e-22 80.5 0.0 1.5 1 1 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_5 PF13433.6 AIM19839.1 - 8.8e-19 67.7 0.0 1.1e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain Fe-ADH PF00465.19 AIM19839.1 - 0.00034 19.5 0.0 0.0006 18.7 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase PGM_PMM_I PF02878.16 AIM19839.1 - 0.024 14.3 0.9 2.1 8.1 0.0 2.9 3 1 0 3 3 3 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I BPD_transp_2 PF02653.16 AIM19840.1 - 1.8e-65 220.8 43.0 2.1e-65 220.6 43.0 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component CreD PF06123.12 AIM19840.1 - 0.39 9.4 7.0 0.86 8.3 7.0 1.6 1 0 0 1 1 1 0 Inner membrane protein CreD BPD_transp_2 PF02653.16 AIM19841.1 - 4.7e-58 196.5 26.4 4.7e-58 196.5 26.4 2.2 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component DUF3382 PF11862.8 AIM19841.1 - 6.2e-25 87.3 8.2 6.2e-25 87.3 8.2 3.8 5 1 0 5 5 5 1 Domain of unknown function (DUF3382) UPF0093 PF03653.13 AIM19841.1 - 7 6.9 10.4 0.92 9.7 1.8 2.6 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0093) ABC_tran PF00005.27 AIM19842.1 - 4.5e-32 111.4 0.0 5.9e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 ABC transporter BCA_ABC_TP_C PF12399.8 AIM19842.1 - 9.8e-12 44.5 0.1 1.7e-11 43.7 0.1 1.4 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_21 PF13304.6 AIM19842.1 - 3.8e-06 26.9 0.1 0.0011 18.9 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AIM19842.1 - 0.00048 20.7 0.4 0.00075 20.0 0.4 1.2 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 AIM19842.1 - 0.0028 17.1 0.0 0.29 10.6 0.1 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AIM19842.1 - 0.0028 17.9 1.2 0.17 12.2 1.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AIM19842.1 - 0.0029 17.3 0.2 0.015 15.0 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AIM19842.1 - 0.0034 17.8 0.3 0.0061 17.0 0.3 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.6 AIM19842.1 - 0.014 15.1 0.1 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 AIM19842.1 - 0.014 15.1 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AIM19842.1 - 0.041 13.8 0.0 0.083 12.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_19 PF13245.6 AIM19842.1 - 0.046 14.0 0.1 0.099 13.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AIM19842.1 - 0.084 12.4 0.6 1.2 8.7 0.0 2.3 2 1 0 2 2 2 0 AAA domain FeoB_N PF02421.18 AIM19842.1 - 0.11 12.0 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B ABC_tran PF00005.27 AIM19843.1 - 7.5e-34 117.2 0.0 1e-33 116.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIM19843.1 - 1.3e-10 41.5 0.1 9.1e-05 22.4 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AIM19843.1 - 0.0012 19.2 0.5 0.0027 18.1 0.5 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AIM19843.1 - 0.0012 18.5 0.1 0.0027 17.4 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AIM19843.1 - 0.0052 16.7 0.3 0.011 15.7 0.1 1.6 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 AIM19843.1 - 0.0054 16.2 0.2 1.9 7.8 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_13 PF13166.6 AIM19843.1 - 0.0067 15.1 0.0 0.011 14.5 0.0 1.3 1 1 0 1 1 1 1 AAA domain BCA_ABC_TP_C PF12399.8 AIM19843.1 - 0.0067 16.3 0.1 0.012 15.6 0.1 1.4 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter MMR_HSR1 PF01926.23 AIM19843.1 - 0.0095 16.0 0.0 0.028 14.5 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_30 PF13604.6 AIM19843.1 - 0.016 15.0 0.6 0.044 13.5 0.6 1.8 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AIM19843.1 - 0.031 14.4 0.1 0.068 13.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 AIM19843.1 - 0.031 13.5 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Septin cobW PF02492.19 AIM19843.1 - 0.044 13.4 0.0 0.086 12.4 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 AIM19843.1 - 0.049 14.1 1.1 0.065 13.7 0.3 1.6 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 AIM19843.1 - 0.051 13.2 0.3 0.097 12.3 0.3 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain SRP54 PF00448.22 AIM19843.1 - 0.07 12.8 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain SbcCD_C PF13558.6 AIM19843.1 - 0.071 13.4 0.3 0.61 10.4 0.3 2.5 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 AIM19843.1 - 0.084 12.8 1.5 0.26 11.2 0.1 2.2 2 1 0 2 2 2 0 NACHT domain Roc PF08477.13 AIM19843.1 - 0.1 12.8 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 AIM19843.1 - 0.11 12.0 0.3 0.28 10.7 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 AIM19843.1 - 0.12 12.5 0.0 0.57 10.2 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_15 PF13175.6 AIM19843.1 - 0.12 12.1 0.1 0.12 12.1 0.1 1.5 2 0 0 2 2 2 0 AAA ATPase domain TsaE PF02367.17 AIM19843.1 - 0.14 12.1 0.1 0.28 11.2 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 AIM19843.1 - 0.22 11.8 1.2 0.79 10.0 1.2 2.0 1 1 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 AIM19843.1 - 0.24 10.2 1.0 10 4.8 0.9 2.7 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_28 PF13521.6 AIM19843.1 - 0.82 9.9 2.8 0.82 9.9 1.4 1.8 2 1 0 2 2 2 0 AAA domain Aminotran_1_2 PF00155.21 AIM19844.1 - 7.7e-36 124.0 0.0 8.6e-36 123.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 AIM19844.1 - 1.7e-09 37.0 0.0 3.4e-09 36.0 0.0 1.5 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.17 AIM19844.1 - 0.0018 17.7 0.1 0.0028 17.0 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 AIM19844.1 - 0.093 11.2 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme SBP_bac_8 PF13416.6 AIM19845.1 - 4.1e-40 138.4 11.6 5e-40 138.1 11.6 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AIM19845.1 - 2.6e-33 116.3 10.1 3.7e-33 115.8 10.1 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AIM19845.1 - 0.0029 17.1 0.2 0.42 10.0 0.0 2.3 2 0 0 2 2 2 2 Bacterial extracellular solute-binding protein BPD_transp_1 PF00528.22 AIM19846.1 - 1.8e-19 70.2 20.1 1.8e-19 70.2 20.1 1.8 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 AIM19847.1 - 3.8e-21 75.7 17.9 3.8e-21 75.7 17.9 2.0 2 0 0 2 2 2 2 Binding-protein-dependent transport system inner membrane component VirB3 PF05101.13 AIM19847.1 - 0.092 13.0 0.3 0.092 13.0 0.3 3.9 3 2 0 3 3 3 0 Type IV secretory pathway, VirB3-like protein ABC_tran PF00005.27 AIM19848.1 - 9.3e-31 107.2 0.0 1.5e-30 106.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter OB_MalK PF17912.1 AIM19848.1 - 3.6e-16 59.7 0.0 1.3e-15 57.9 0.0 2.1 1 0 0 1 1 1 1 MalK OB fold domain TOBE_2 PF08402.10 AIM19848.1 - 1.6e-07 31.4 0.1 4.2e-07 30.0 0.1 1.8 1 0 0 1 1 1 1 TOBE domain CysA_C_terminal PF17850.1 AIM19848.1 - 2.7e-06 27.9 0.0 6.1e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 CysA C-terminal regulatory domain AAA_21 PF13304.6 AIM19848.1 - 3.5e-06 27.1 0.0 0.021 14.6 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AIM19848.1 - 3.1e-05 24.4 0.0 5.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AIM19848.1 - 0.00023 21.1 0.0 0.00045 20.1 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 AIM19848.1 - 0.0029 17.9 0.1 0.0059 16.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 AIM19848.1 - 0.0034 16.8 0.1 0.19 11.2 0.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 AIM19848.1 - 0.0038 17.4 0.1 0.0061 16.7 0.1 1.6 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 AIM19848.1 - 0.0043 17.0 0.0 0.0063 16.5 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Rad17 PF03215.15 AIM19848.1 - 0.011 15.7 0.0 0.016 15.2 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_29 PF13555.6 AIM19848.1 - 0.012 15.4 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mg_chelatase PF01078.21 AIM19848.1 - 0.013 14.9 0.0 0.036 13.4 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 AIM19848.1 - 0.018 14.6 0.1 0.054 13.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 AIM19848.1 - 0.048 14.2 0.0 0.077 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 AIM19848.1 - 0.057 13.7 0.3 0.14 12.4 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 AIM19848.1 - 0.062 13.7 0.0 0.13 12.7 0.0 1.6 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 AIM19848.1 - 0.081 13.0 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase NACHT PF05729.12 AIM19848.1 - 0.099 12.5 1.6 0.22 11.4 0.1 2.1 2 1 0 2 2 2 0 NACHT domain AAA_14 PF13173.6 AIM19848.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 AIM19848.1 - 0.13 12.3 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Dynamin family RNA_helicase PF00910.22 AIM19848.1 - 0.13 12.6 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.12 AIM19848.1 - 0.14 11.4 0.1 0.33 10.2 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin NB-ARC PF00931.22 AIM19848.1 - 0.15 11.2 0.1 0.34 10.1 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain AAA_5 PF07728.14 AIM19848.1 - 0.17 11.8 0.6 0.45 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) GDPD PF03009.17 AIM19849.1 - 2.7e-40 138.8 0.0 3.2e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 AIM19849.1 - 0.00026 21.3 0.3 0.00026 21.3 0.3 2.4 3 0 0 3 3 3 1 Glycerophosphoryl diester phosphodiesterase family Mem_trans PF03547.18 AIM19850.1 - 3.5e-27 94.8 24.4 1.2e-14 53.5 10.7 2.0 1 1 0 2 2 2 2 Membrane transport protein NBD_C PF17042.5 AIM19850.1 - 0.0026 18.3 0.3 0.0048 17.4 0.3 1.3 1 0 0 1 1 1 1 Nucleotide-binding C-terminal domain DUF1616 PF07760.11 AIM19850.1 - 0.86 8.9 4.7 0.11 11.9 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1616) DUF5516 PF17637.2 AIM19850.1 - 2.1 8.1 6.9 0.93 9.3 0.2 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5516) Androgen_recep PF02166.16 AIM19851.1 - 1.5 7.6 15.0 1.7 7.4 15.0 1.0 1 0 0 1 1 1 0 Androgen receptor Rrn6 PF10214.9 AIM19851.1 - 2.1 6.8 8.5 2.2 6.7 8.5 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor EamA PF00892.20 AIM19852.1 - 5e-22 78.6 36.6 6.9e-12 45.7 9.8 2.0 2 0 0 2 2 2 2 EamA-like transporter family DUF1634 PF07843.11 AIM19852.1 - 0.022 14.8 4.7 5.1 7.2 0.1 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1634) Phtf-FEM1B_bdg PF12129.8 AIM19852.1 - 0.22 11.3 1.4 0.5 10.2 1.4 1.5 1 0 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor LysR_substrate PF03466.20 AIM19853.1 - 5.2e-42 143.6 2.6 7.9e-42 143.0 2.6 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM19853.1 - 5.5e-16 58.3 2.6 1.1e-15 57.4 2.6 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AIM19853.1 - 0.051 13.4 0.2 0.14 12.0 0.2 1.7 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Meth_synt_2 PF01717.18 AIM19854.1 - 2.5e-165 549.5 0.0 2.2e-157 523.4 0.0 2.4 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 AIM19854.1 - 7.6e-136 452.7 0.0 1.8e-126 421.9 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain DLH PF01738.18 AIM19855.1 - 1.6e-74 250.1 0.0 1.9e-74 249.9 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 AIM19855.1 - 8.7e-07 29.1 0.6 0.25 11.2 0.0 3.3 1 1 2 3 3 3 3 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 AIM19855.1 - 3.9e-06 26.8 0.0 6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 AIM19855.1 - 5e-06 26.1 0.0 0.0029 17.1 0.0 2.1 1 1 1 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 AIM19855.1 - 1.2e-05 24.7 0.1 0.085 12.1 0.0 2.8 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AIM19855.1 - 1.5e-05 24.7 0.0 0.0032 17.1 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 AIM19855.1 - 0.0036 16.2 0.0 0.0052 15.7 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S15 PF02129.18 AIM19855.1 - 0.0058 16.3 0.7 0.011 15.4 0.7 1.7 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Chlorophyllase PF07224.11 AIM19855.1 - 0.022 13.8 0.0 0.031 13.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Abhydrolase_3 PF07859.13 AIM19855.1 - 0.066 13.1 0.5 1.2 8.9 0.0 2.4 2 1 1 3 3 3 0 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 AIM19855.1 - 0.099 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein PNP_UDP_1 PF01048.20 AIM19856.1 - 1.9e-39 135.3 3.0 2.1e-39 135.2 3.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Y_phosphatase3 PF13350.6 AIM19857.1 - 1.3e-58 198.7 0.0 1.5e-58 198.6 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family SNARE_assoc PF09335.11 AIM19858.1 - 1.5e-13 51.3 8.5 1.5e-13 51.3 8.5 1.4 2 0 0 2 2 2 1 SNARE associated Golgi protein Phage_holin_5_1 PF06946.11 AIM19858.1 - 4.6 7.7 6.4 24 5.4 0.1 2.2 2 0 0 2 2 2 0 Bacteriophage A118-like holin, Hol118 RmuC PF02646.16 AIM19859.1 - 1.1e-105 352.9 0.2 1.1e-105 352.9 0.2 2.5 2 1 1 3 3 3 1 RmuC family LapA_dom PF06305.11 AIM19859.1 - 0.007 16.2 0.5 0.007 16.2 0.5 2.7 4 0 0 4 4 4 1 Lipopolysaccharide assembly protein A domain DUF3456 PF11938.8 AIM19859.1 - 0.18 12.3 4.1 0.13 12.8 1.8 1.9 1 1 0 1 1 1 0 TLR4 regulator and MIR-interacting MSAP TPD PF14811.6 AIM19859.1 - 1.6 8.6 3.5 1.1 9.2 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function TPD sequence-motif PHM7_cyt PF14703.6 AIM19859.1 - 3.8 7.7 12.3 1.2 9.3 6.7 2.6 3 0 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Ubie_methyltran PF01209.18 AIM19860.1 - 5e-106 353.3 0.0 5.7e-106 353.1 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 AIM19860.1 - 6e-24 84.6 0.0 1.1e-23 83.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AIM19860.1 - 2.8e-22 79.2 0.0 4.9e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AIM19860.1 - 9.2e-19 67.7 0.0 1.7e-18 66.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AIM19860.1 - 1.1e-16 61.1 0.0 1.6e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIM19860.1 - 3.3e-13 50.2 0.0 5.9e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 AIM19860.1 - 1.5e-07 31.4 0.0 2.4e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 AIM19860.1 - 5.7e-05 22.7 0.0 0.00011 21.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.18 AIM19860.1 - 0.0037 17.0 0.0 0.01 15.5 0.0 1.9 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 MetW PF07021.12 AIM19860.1 - 0.0057 16.3 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW GCD14 PF08704.10 AIM19860.1 - 0.0092 15.7 0.0 0.04 13.6 0.0 1.8 1 1 1 2 2 2 1 tRNA methyltransferase complex GCD14 subunit RrnaAD PF00398.20 AIM19860.1 - 0.15 11.1 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase SCP2 PF02036.17 AIM19861.1 - 3.3e-17 62.8 0.0 5.2e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 AIM19861.1 - 0.0028 17.9 0.0 0.0046 17.2 0.0 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal ABC1 PF03109.16 AIM19862.1 - 2.6e-35 121.1 0.0 5.2e-35 120.2 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Protoglobin PF11563.8 AIM19862.1 - 0.0039 17.1 0.1 0.014 15.3 0.1 1.9 2 0 0 2 2 2 1 Protoglobin MttA_Hcf106 PF02416.16 AIM19863.1 - 1.9e-06 27.1 0.0 1.9e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 mttA/Hcf106 family MttA_Hcf106 PF02416.16 AIM19864.1 - 0.0015 17.8 2.8 0.0028 16.9 2.8 1.7 1 1 0 1 1 1 1 mttA/Hcf106 family Rx_N PF18052.1 AIM19864.1 - 0.1 12.9 0.8 0.44 10.8 0.6 1.8 1 1 1 2 2 2 0 Rx N-terminal domain TatC PF00902.18 AIM19865.1 - 1.2e-64 218.0 22.0 1.2e-64 218.0 22.0 1.3 2 0 0 2 2 2 1 Sec-independent protein translocase protein (TatC) TatD_DNase PF01026.21 AIM19866.1 - 1.3e-67 227.8 0.0 1.5e-67 227.6 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase DUF2293 PF10056.9 AIM19866.1 - 0.084 13.1 0.2 0.58 10.4 0.0 2.3 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2293) E1_dh PF00676.20 AIM19866.1 - 0.13 11.2 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component ALAD PF00490.21 AIM19867.1 - 3.5e-139 463.4 0.0 4e-139 463.2 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase AP_endonuc_2 PF01261.24 AIM19867.1 - 0.11 11.9 0.0 0.29 10.6 0.0 1.7 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel NusG PF02357.19 AIM19868.1 - 7.9e-18 64.8 0.0 1.2e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 Transcription termination factor nusG Peptidase_S51 PF03575.17 AIM19869.1 - 1.2e-44 152.4 0.0 1.4e-44 152.2 0.0 1.0 1 0 0 1 1 1 1 Peptidase family S51 UbiD PF01977.16 AIM19870.1 - 6.5e-175 581.8 0.0 7.4e-175 581.6 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase NAD_binding_1 PF00175.21 AIM19871.1 - 1e-21 77.6 0.0 1.6e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 AIM19871.1 - 2.7e-05 24.5 0.0 4.2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain FAD_binding_8 PF08022.12 AIM19871.1 - 0.0019 18.3 0.0 0.0032 17.5 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 AIM19871.1 - 0.019 15.1 0.0 0.031 14.4 0.0 1.2 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Thiolase_N PF00108.23 AIM19872.1 - 1.5e-86 290.0 0.3 2e-86 289.6 0.3 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 AIM19872.1 - 2.8e-50 169.1 0.1 2.8e-50 169.1 0.1 1.6 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 AIM19872.1 - 0.0019 17.8 1.5 0.0025 17.5 0.1 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain 3HCDH_N PF02737.18 AIM19873.1 - 1.2e-60 204.4 1.2 2.4e-60 203.5 0.2 2.0 2 1 1 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 AIM19873.1 - 1e-43 149.5 0.0 2.2e-43 148.4 0.0 1.5 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 AIM19873.1 - 8.1e-33 112.9 2.0 5.2e-25 87.9 0.1 3.0 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 AIM19873.1 - 4.1e-25 89.0 0.0 7.1e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase NAD_binding_2 PF03446.15 AIM19873.1 - 0.038 14.2 0.2 0.1 12.8 0.2 1.7 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase MFS_1 PF07690.16 AIM19874.1 - 2.7e-33 115.4 52.2 2.7e-33 115.4 52.2 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AIM19874.1 - 2.8e-07 29.8 11.8 2.8e-07 29.8 11.8 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter Peptidase_M24 PF00557.24 AIM19875.1 - 4.6e-44 150.6 0.2 7.1e-44 150.0 0.1 1.3 2 0 0 2 2 2 1 Metallopeptidase family M24 DUF3581 PF12119.8 AIM19875.1 - 0.035 13.5 0.0 0.055 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3581) UPF0029 PF01205.19 AIM19876.1 - 2.6e-28 98.4 0.0 3.5e-28 98.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 DUF1949 PF09186.11 AIM19876.1 - 1e-17 63.7 0.2 3.3e-17 62.1 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1949) EFG_C PF00679.24 AIM19876.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Elongation factor G C-terminus TrkH PF02386.16 AIM19877.1 - 4.6e-89 299.1 14.0 6.8e-89 298.6 14.0 1.2 1 0 0 1 1 1 1 Cation transport protein TMEM138 PF14935.6 AIM19877.1 - 0.0061 17.2 0.1 0.0061 17.2 0.1 2.7 3 0 0 3 3 3 1 Transmembrane protein 138 Flavodoxin_5 PF12724.7 AIM19878.1 - 1.2e-56 191.0 0.0 1.5e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_3 PF12641.7 AIM19878.1 - 6.3e-06 26.0 0.0 1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_1 PF00258.25 AIM19878.1 - 0.0016 18.6 0.0 0.0021 18.3 0.0 1.5 1 1 0 1 1 1 1 Flavodoxin SEFIR PF08357.11 AIM19878.1 - 0.0098 16.2 0.0 0.035 14.4 0.0 1.9 1 1 1 2 2 2 1 SEFIR domain MurB_C PF02873.16 AIM19879.1 - 2.3e-41 140.6 0.0 3.7e-41 139.9 0.0 1.3 1 0 0 1 1 1 1 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain FAD_binding_4 PF01565.23 AIM19879.1 - 1.7e-20 73.2 0.0 3.8e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain BPL_LplA_LipB PF03099.19 AIM19880.1 - 5.2e-24 84.6 0.0 7.7e-24 84.1 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 AIM19880.1 - 2.3e-12 46.6 0.6 2.3e-12 46.6 0.6 2.1 2 0 0 2 2 2 1 Biotin protein ligase C terminal domain HTH_11 PF08279.12 AIM19880.1 - 2.4e-11 43.4 0.0 5.6e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 HTH domain BPL_LplA_LipB_2 PF16917.5 AIM19880.1 - 0.00023 20.8 0.1 0.00034 20.2 0.1 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family HTH_29 PF13551.6 AIM19880.1 - 0.064 13.3 0.0 0.29 11.2 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn helix PRK PF00485.18 AIM19881.1 - 3.8e-15 56.2 0.0 5.7e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 AIM19881.1 - 0.036 14.6 0.0 0.084 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain CoaE PF01121.20 AIM19881.1 - 0.076 12.7 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Dephospho-CoA kinase AAA_22 PF13401.6 AIM19881.1 - 0.12 12.7 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 AIM19881.1 - 0.18 11.1 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Acetyltransf_10 PF13673.7 AIM19882.1 - 9.7e-13 48.2 0.0 1.3e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AIM19882.1 - 5.1e-11 42.8 0.0 6.9e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AIM19882.1 - 1.8e-09 37.9 0.0 3.3e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AIM19882.1 - 3e-05 23.9 0.8 0.00037 20.4 0.2 2.3 2 1 1 3 3 3 1 FR47-like protein Acetyltransf_4 PF13420.7 AIM19882.1 - 0.0021 18.2 0.0 0.0027 17.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PHM7_ext PF12621.8 AIM19882.1 - 0.17 12.1 0.0 0.25 11.6 0.0 1.3 1 0 0 1 1 1 0 Extracellular tail, of 10TM putative phosphate transporter GTP_EFTU PF00009.27 AIM19883.1 - 3.7e-59 199.5 0.0 5e-59 199.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 AIM19883.1 - 1.3e-33 115.6 0.0 2.5e-33 114.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 AIM19883.1 - 1.3e-17 63.9 6.5 3.4e-17 62.6 6.5 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 AIM19883.1 - 6.4e-05 23.0 0.0 0.00013 22.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Lsm_C PF14894.6 AIM19883.1 - 0.11 12.4 3.2 0.23 11.3 3.2 1.5 1 0 0 1 1 1 0 Lsm C-terminal cobW PF02492.19 AIM19883.1 - 0.11 12.1 0.3 0.22 11.1 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SecE PF00584.20 AIM19884.1 - 6.4e-20 70.8 1.2 6.4e-20 70.8 1.2 2.9 3 0 0 3 3 3 1 SecE/Sec61-gamma subunits of protein translocation complex TRIQK PF15168.6 AIM19884.1 - 0.036 14.0 0.7 0.25 11.2 0.0 2.3 2 1 0 2 2 2 0 Triple QxxK/R motif-containing protein family EptA_B_N PF08019.12 AIM19884.1 - 0.11 12.4 5.5 0.037 13.9 1.9 1.9 1 1 1 2 2 2 0 Phosphoethanolamine transferase EptA/EptB Herpes_LMP1 PF05297.11 AIM19884.1 - 0.56 9.3 2.7 0.25 10.5 0.2 1.5 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) NusG PF02357.19 AIM19885.1 - 1.5e-27 95.9 0.0 2.2e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 Transcription termination factor nusG KOW PF00467.29 AIM19885.1 - 1.8e-08 34.0 0.0 1e-07 31.6 0.1 2.1 2 0 0 2 2 2 1 KOW motif Ribosomal_L11_N PF03946.14 AIM19886.1 - 2.6e-32 110.4 0.3 4.5e-32 109.7 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 AIM19886.1 - 6.9e-27 93.8 2.1 1e-26 93.2 2.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain DUF3140 PF11338.8 AIM19886.1 - 0.021 15.3 0.4 0.063 13.7 0.2 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3140) Ribosomal_L1 PF00687.21 AIM19887.1 - 9.8e-53 178.9 0.1 1.2e-52 178.6 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ribosomal_L10 PF00466.20 AIM19888.1 - 1e-26 93.0 0.0 1.5e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 DUF349 PF03993.12 AIM19888.1 - 0.34 11.2 2.9 0.44 10.9 0.0 2.3 2 1 0 2 2 2 0 Domain of Unknown Function (DUF349) Ribosomal_L12 PF00542.19 AIM19889.1 - 4.4e-31 107.0 8.0 4.4e-31 107.0 8.0 1.7 2 1 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 AIM19889.1 - 2.8e-17 62.1 12.0 2.8e-17 62.1 12.0 3.2 3 1 1 4 4 4 1 Ribosomal protein L7/L12 dimerisation domain RNA_pol_Rpb2_6 PF00562.28 AIM19890.1 - 1.9e-161 537.5 0.4 3.2e-160 533.4 0.7 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 AIM19890.1 - 1.5e-57 194.5 0.0 3.6e-57 193.2 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 AIM19890.1 - 2.8e-31 107.5 0.0 9e-31 105.9 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_45 PF10385.9 AIM19890.1 - 3.7e-28 97.6 0.1 4.9e-27 94.0 0.2 2.8 2 0 0 2 2 2 1 RNA polymerase beta subunit external 1 domain RNA_pol_Rpb2_7 PF04560.20 AIM19890.1 - 1.1e-27 96.2 0.0 3.6e-27 94.6 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 AIM19890.1 - 2.9e-25 89.0 0.5 8.6e-15 54.9 0.1 3.0 3 0 0 3 3 3 2 RNA polymerase Rpb2, domain 2 Spc7 PF08317.11 AIM19890.1 - 0.46 9.3 4.8 1.2 8.0 4.8 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein RNA_pol_Rpb1_1 PF04997.12 AIM19891.1 - 1.6e-89 300.3 0.0 2.4e-89 299.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 AIM19891.1 - 9.1e-78 261.4 0.0 1.5e-77 260.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 AIM19891.1 - 9.2e-38 130.1 0.1 4.1e-27 95.4 0.0 3.1 2 1 1 3 3 3 2 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 AIM19891.1 - 8.3e-27 94.1 0.0 1.9e-26 92.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 AIM19891.1 - 5e-19 68.2 0.1 1.4e-18 66.8 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DUF3150 PF11348.8 AIM19891.1 - 0.12 11.6 0.1 0.24 10.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) Acetyltransf_1 PF00583.25 AIM19892.1 - 3.2e-14 53.2 0.1 3.8e-14 52.9 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AIM19892.1 - 3.8e-11 43.0 0.0 4.7e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AIM19892.1 - 5e-09 36.5 0.0 7.1e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AIM19892.1 - 0.00036 20.6 0.0 0.00069 19.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AIM19892.1 - 0.00077 19.4 0.0 0.0012 18.8 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Oxidored_molyb PF00174.19 AIM19893.1 - 0.02 14.5 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 Oxidoreductase molybdopterin binding domain HATPase_c PF02518.26 AIM19894.1 - 9.3e-19 68.0 0.0 2.1e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AIM19894.1 - 0.0062 16.4 0.2 0.022 14.7 0.2 2.0 1 0 0 1 1 1 1 GHKL domain Response_reg PF00072.24 AIM19895.1 - 1.3e-05 25.3 0.2 2e-05 24.7 0.2 1.3 1 0 0 1 1 1 1 Response regulator receiver domain BetR PF08667.10 AIM19895.1 - 0.00035 20.6 0.0 0.0037 17.3 0.0 2.5 2 1 0 2 2 2 1 BetR domain Methyltransf_31 PF13847.6 AIM19895.1 - 0.025 14.4 0.1 0.065 13.0 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain DUF43 PF01861.16 AIM19895.1 - 0.064 12.5 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain BATS PF06968.13 AIM19896.1 - 5.4e-24 84.2 0.0 1.1e-23 83.1 0.0 1.6 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 AIM19896.1 - 2.3e-09 37.8 0.0 4.3e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily SecM PF06558.12 AIM19896.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Secretion monitor precursor protein (SecM) ThiG PF05690.14 AIM19897.1 - 9.8e-109 362.4 1.9 1.1e-108 362.2 1.9 1.0 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 AIM19897.1 - 0.00011 21.7 0.0 0.00037 20.0 0.0 1.7 2 0 0 2 2 2 1 Histidine biosynthesis protein FMN_dh PF01070.18 AIM19897.1 - 0.0012 17.9 0.3 0.0019 17.3 0.3 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NanE PF04131.14 AIM19897.1 - 0.0068 15.6 0.1 0.016 14.4 0.1 1.6 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase IMPDH PF00478.25 AIM19897.1 - 0.036 13.1 0.2 0.051 12.6 0.2 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain ThiS PF02597.20 AIM19898.1 - 8.2e-15 55.2 0.0 9.5e-15 55.0 0.0 1.0 1 0 0 1 1 1 1 ThiS family ThiS-like PF14453.6 AIM19898.1 - 0.035 14.2 0.0 1.7 8.7 0.0 2.2 2 1 0 2 2 2 0 ThiS-like ubiquitin ThiF PF00899.21 AIM19899.1 - 1.6e-60 204.5 0.0 1.9e-60 204.2 0.0 1.0 1 0 0 1 1 1 1 ThiF family NAD_binding_7 PF13241.6 AIM19899.1 - 0.0061 17.0 0.0 0.011 16.2 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 AIM19899.1 - 0.014 14.8 0.1 0.5 9.7 0.0 2.3 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 AIM19899.1 - 0.044 14.1 0.4 0.18 12.1 0.4 1.8 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain FAD_binding_3 PF01494.19 AIM19899.1 - 0.079 12.2 0.2 0.11 11.8 0.2 1.1 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.20 AIM19899.1 - 0.2 11.7 0.0 0.48 10.5 0.0 1.6 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase TMP-TENI PF02581.17 AIM19900.1 - 4.2e-56 189.1 0.3 5.3e-56 188.8 0.3 1.0 1 0 0 1 1 1 1 Thiamine monophosphate synthase DHBP_synthase PF00926.19 AIM19900.1 - 0.093 12.2 0.1 0.15 11.6 0.1 1.2 1 0 0 1 1 1 0 3,4-dihydroxy-2-butanone 4-phosphate synthase UIM PF02809.20 AIM19900.1 - 2.2 8.4 8.7 12 6.1 1.0 2.6 2 0 0 2 2 2 0 Ubiquitin interaction motif ThiC_Rad_SAM PF01964.18 AIM19901.1 - 6.8e-200 664.2 0.0 8.9e-200 663.8 0.0 1.1 1 0 0 1 1 1 1 Radical SAM ThiC family ThiC-associated PF13667.6 AIM19901.1 - 3.7e-32 110.0 0.1 1e-31 108.6 0.0 1.8 2 0 0 2 2 2 1 ThiC-associated domain Rsd_AlgQ PF04353.13 AIM19902.1 - 1.1e-55 187.7 0.1 1.3e-55 187.5 0.1 1.0 1 0 0 1 1 1 1 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ NUDIX PF00293.28 AIM19903.1 - 1.6e-17 63.8 0.0 2.9e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.11 AIM19903.1 - 7.9e-08 31.8 10.5 1.7e-07 30.8 10.5 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain DUF1451 PF07295.11 AIM19903.1 - 0.24 11.4 3.9 0.5 10.4 3.9 1.5 1 0 0 1 1 1 0 Zinc-ribbon containing domain PknG_rubred PF16919.5 AIM19903.1 - 6.6 6.9 5.2 7.9 6.6 3.8 1.8 1 1 1 2 2 2 0 Protein kinase G rubredoxin domain URO-D PF01208.17 AIM19904.1 - 3.7e-141 470.3 0.0 4.2e-141 470.1 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Endonuclease_5 PF04493.14 AIM19905.1 - 2.9e-70 236.0 0.0 3.5e-70 235.7 0.0 1.0 1 0 0 1 1 1 1 Endonuclease V BRK PF07533.16 AIM19905.1 - 0.14 11.8 0.5 8.7 6.1 0.1 2.5 2 0 0 2 2 2 0 BRK domain DUF416 PF04222.12 AIM19906.1 - 5.6e-78 260.7 0.0 6.3e-78 260.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF416) Bac_DNA_binding PF00216.21 AIM19907.1 - 2.9e-32 110.7 0.6 3.1e-32 110.6 0.6 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 AIM19907.1 - 2e-08 34.4 0.1 2.1e-08 34.3 0.1 1.0 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_bac_2 PF18175.1 AIM19907.1 - 7.5e-06 25.7 0.0 1e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 CCDC81-like prokaryotic HU domain 2 HU-CCDC81_euk_2 PF18289.1 AIM19907.1 - 0.0017 18.4 0.0 0.0024 18.0 0.0 1.2 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 HU-CCDC81_euk_1 PF14908.6 AIM19907.1 - 0.002 18.3 0.0 0.0022 18.1 0.0 1.1 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 1 DUF1481 PF07356.12 AIM19908.1 - 3.8e-73 245.2 0.0 4.3e-73 245.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1481) GARS_A PF01071.19 AIM19909.1 - 5.4e-84 280.8 0.1 7.2e-84 280.4 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 AIM19909.1 - 5.7e-36 123.2 0.3 1.5e-35 121.8 0.3 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 AIM19909.1 - 1.1e-30 105.7 0.5 1.3e-29 102.3 0.1 2.5 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain CPSase_L_D2 PF02786.17 AIM19909.1 - 5.6e-07 29.3 0.0 1e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 AIM19909.1 - 2.4e-06 27.7 0.0 4.8e-06 26.7 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 AIM19909.1 - 0.00012 21.7 0.0 0.0002 20.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 AIM19909.1 - 0.0015 18.1 0.0 0.0031 17.1 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.6 AIM19909.1 - 0.0067 16.0 0.0 0.017 14.7 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_2 PF08442.10 AIM19909.1 - 0.1 12.1 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp domain AICARFT_IMPCHas PF01808.18 AIM19910.1 - 1.2e-119 399.1 5.5 1.6e-119 398.8 5.5 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 AIM19910.1 - 6.8e-31 106.3 0.0 2e-30 104.8 0.0 1.8 1 0 0 1 1 1 1 MGS-like domain CoA_binding_2 PF13380.6 AIM19910.1 - 5.7 7.5 6.2 2.6 8.5 0.0 3.2 4 1 1 5 5 5 0 CoA binding domain SSF PF00474.17 AIM19911.1 - 2.3e-128 428.5 40.2 3e-128 428.1 40.2 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family DUF2818 PF10993.8 AIM19911.1 - 0.098 13.2 0.1 0.098 13.2 0.1 3.3 4 1 0 4 4 4 0 Protein of unknown function (DUF2818) DUF2784 PF10861.8 AIM19911.1 - 2.7 8.0 12.7 0.36 10.9 5.2 3.2 3 0 0 3 3 3 0 Protein of Unknown function (DUF2784) DUF485 PF04341.12 AIM19912.1 - 2.1e-35 120.5 0.1 2.4e-35 120.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF485 DUF2207 PF09972.9 AIM19912.1 - 0.15 10.8 0.3 0.16 10.7 0.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3099 PF11298.8 AIM19912.1 - 0.18 12.0 0.3 0.97 9.6 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3099) FixS PF03597.15 AIM19912.1 - 7.9 6.3 7.3 10 5.9 3.1 2.3 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type AMP-binding PF00501.28 AIM19913.1 - 3.6e-92 309.2 0.0 4.5e-92 308.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AIM19913.1 - 1.4e-26 93.2 0.0 3.5e-26 92.0 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 AIM19913.1 - 3.5e-21 74.9 0.3 9.9e-21 73.4 0.3 1.9 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus SDF PF00375.18 AIM19914.1 - 1e-118 396.8 35.4 1.2e-118 396.6 35.4 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family PRF PF06875.11 AIM19914.1 - 0.1 12.0 0.1 0.3 10.5 0.1 1.8 1 0 0 1 1 1 0 Plethodontid receptivity factor PRF Condensation PF00668.20 AIM19915.1 - 4.2e-35 121.3 0.0 5.2e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Condensation domain AMP-binding PF00501.28 AIM19916.1 - 2.1e-78 263.8 0.0 3.5e-78 263.1 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 AIM19916.1 - 4.3e-14 52.0 3.6 4.3e-06 25.7 1.8 2.5 3 0 0 3 3 3 2 Condensation domain AMP-binding_C PF13193.6 AIM19916.1 - 4.6e-05 24.3 0.0 0.00011 23.1 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Condensation PF00668.20 AIM19917.1 - 1.2e-32 113.2 0.0 1.5e-32 112.9 0.0 1.1 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.25 AIM19917.1 - 0.0044 17.3 0.1 0.013 15.8 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site TonB_dep_Rec PF00593.24 AIM19918.1 - 8.3e-40 138.0 24.6 8.3e-40 138.0 24.6 1.6 2 0 0 2 2 2 1 TonB dependent receptor OMP_b-brl_3 PF14905.6 AIM19918.1 - 2.1e-13 50.0 2.6 1.7e-08 33.9 2.3 2.2 2 0 0 2 2 2 2 Outer membrane protein beta-barrel family Plug PF07715.15 AIM19918.1 - 4.7e-09 36.8 0.4 9.8e-09 35.7 0.4 1.6 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain DUF3443 PF11925.8 AIM19918.1 - 0.13 11.1 0.1 0.2 10.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3443) Condensation PF00668.20 AIM19919.1 - 2.1e-58 198.1 0.0 1.6e-52 178.7 0.0 2.1 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.25 AIM19919.1 - 3.8e-10 40.0 0.0 1.1e-09 38.5 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site SGL PF08450.12 AIM19920.1 - 0.00013 21.6 0.0 0.0068 16.0 0.0 2.9 3 0 0 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region PQQ PF01011.21 AIM19920.1 - 0.002 18.0 1.2 0.32 11.0 0.0 4.2 5 0 0 5 5 5 1 PQQ enzyme repeat Lactonase PF10282.9 AIM19920.1 - 0.0035 16.7 0.0 0.16 11.2 0.0 3.0 3 0 0 3 3 3 1 Lactonase, 7-bladed beta-propeller PQQ_3 PF13570.6 AIM19920.1 - 2.7 8.6 6.2 99 3.6 0.0 4.7 5 0 0 5 5 5 0 PQQ-like domain Plug PF07715.15 AIM19921.1 - 5e-30 104.2 1.7 1.5e-29 102.7 0.7 2.4 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain TonB_dep_Rec PF00593.24 AIM19921.1 - 2.6e-16 60.6 27.1 8.4e-16 58.9 16.6 2.6 1 1 0 2 2 2 2 TonB dependent receptor Esterase PF00756.20 AIM19922.1 - 7.2e-35 120.8 0.2 1.3e-34 120.0 0.2 1.4 1 0 0 1 1 1 1 Putative esterase DUF3327 PF11806.8 AIM19922.1 - 3.4e-34 118.2 1.3 3.4e-34 118.2 1.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3327) Peptidase_S9 PF00326.21 AIM19922.1 - 0.0027 17.2 0.0 0.0055 16.2 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 AIM19922.1 - 0.053 12.8 0.0 0.12 11.6 0.0 1.5 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 AIM19922.1 - 0.12 12.2 0.3 0.44 10.3 0.0 2.0 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase MbtH PF03621.13 AIM19923.1 - 7.1e-15 54.2 0.2 8.7e-15 53.9 0.2 1.1 1 0 0 1 1 1 1 MbtH-like protein AMP-binding PF00501.28 AIM19924.1 - 6.9e-102 341.2 0.0 1.1e-101 340.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 AIM19924.1 - 1.1e-67 228.7 0.0 1.5e-67 228.2 0.0 1.2 1 0 0 1 1 1 1 Condensation domain Thioesterase PF00975.20 AIM19924.1 - 4.1e-38 131.8 3.9 8.4e-36 124.2 0.2 3.0 3 0 0 3 3 3 2 Thioesterase domain PP-binding PF00550.25 AIM19924.1 - 1.2e-10 41.6 0.5 3.4e-10 40.1 0.5 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 AIM19924.1 - 5.7e-08 33.6 0.0 3.7e-07 31.0 0.0 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 AIM19925.1 - 1.1e-20 73.9 60.5 1.9e-14 53.4 30.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 AIM19925.1 - 1.6e-19 69.7 30.5 2e-19 69.4 30.5 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector PTR2 PF00854.21 AIM19925.1 - 0.7 8.7 8.7 0.18 10.6 0.2 2.7 3 0 0 3 3 3 0 POT family Chorismate_bind PF00425.18 AIM19926.1 - 2.9e-74 249.9 0.0 4e-74 249.4 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme AMP-binding PF00501.28 AIM19927.1 - 1.1e-77 261.5 0.0 1.4e-77 261.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AIM19927.1 - 2.3e-11 44.5 0.0 7.9e-11 42.8 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 AIM19927.1 - 0.067 12.0 0.0 0.19 10.5 0.0 1.6 2 0 0 2 2 2 0 GH3 auxin-responsive promoter Isochorismatase PF00857.20 AIM19928.1 - 8.4e-39 133.5 0.0 1.1e-38 133.2 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family PP-binding PF00550.25 AIM19928.1 - 3e-06 27.5 0.1 5.3e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site SGL PF08450.12 AIM19929.1 - 1.1e-10 41.6 0.5 0.00052 19.7 0.2 3.6 1 1 2 3 3 3 3 SMP-30/Gluconolactonase/LRE-like region PQQ PF01011.21 AIM19929.1 - 1.2e-07 31.3 0.7 0.015 15.2 0.2 5.1 4 1 1 5 5 5 1 PQQ enzyme repeat PQQ_2 PF13360.6 AIM19929.1 - 2e-07 30.9 1.6 3.2e-05 23.6 1.6 2.7 1 1 1 2 2 2 2 PQQ-like domain Lactonase PF10282.9 AIM19929.1 - 9.8e-06 25.1 0.4 0.14 11.3 0.0 3.1 1 1 1 3 3 3 3 Lactonase, 7-bladed beta-propeller DUF5074 PF16819.5 AIM19929.1 - 8e-05 22.7 0.1 0.036 14.1 0.0 3.6 2 2 1 3 3 3 1 Domain of unknown function (DUF5074) Cytochrom_D1 PF02239.16 AIM19929.1 - 0.00088 17.9 0.1 0.025 13.1 0.1 2.3 1 1 0 1 1 1 1 Cytochrome D1 heme domain Phytase-like PF13449.6 AIM19929.1 - 0.00091 19.2 0.3 0.018 15.0 0.1 2.6 1 1 1 2 2 2 1 Esterase-like activity of phytase PQQ_3 PF13570.6 AIM19929.1 - 0.0022 18.4 6.0 2.4 8.8 0.0 4.8 5 1 0 5 5 5 1 PQQ-like domain Glu_cyclase_2 PF05096.12 AIM19929.1 - 0.0025 17.3 0.3 1.3 8.4 0.1 2.6 1 1 1 2 2 2 2 Glutamine cyclotransferase DUF2283 PF10049.9 AIM19929.1 - 0.011 16.0 0.1 18 5.7 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2283) MRJP PF03022.16 AIM19929.1 - 0.016 14.6 0.3 0.17 11.2 0.1 2.5 2 1 1 3 3 3 0 Major royal jelly protein Big_6 PF17936.1 AIM19929.1 - 0.1 12.9 0.2 0.1 12.9 0.2 2.8 3 0 0 3 3 3 0 Bacterial Ig domain DUF2238 PF09997.9 AIM19930.1 - 6.7e-54 181.5 0.1 1.1e-53 180.8 0.1 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2238) Trans_reg_C PF00486.28 AIM19931.1 - 3.3e-12 46.3 0.0 5.3e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal FidL_like PF15941.5 AIM19932.1 - 0.00042 20.7 0.0 0.0011 19.4 0.0 1.7 1 1 0 1 1 1 1 FidL-like putative membrane protein Trans_reg_C PF00486.28 AIM19933.1 - 2.8e-10 40.1 0.0 4.4e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Fimbrial PF00419.20 AIM19934.1 - 5.9e-15 55.8 2.7 7.2e-15 55.6 2.7 1.1 1 0 0 1 1 1 1 Fimbrial protein FimA PF16970.5 AIM19934.1 - 0.0017 18.6 2.1 0.0058 16.8 2.1 1.8 1 1 0 1 1 1 1 Type-1 fimbrial protein, A Fimbrial PF00419.20 AIM19935.1 - 0.00021 21.6 0.0 0.00043 20.6 0.0 1.5 1 1 0 1 1 1 1 Fimbrial protein Usher PF00577.20 AIM19936.1 - 1.5e-191 638.1 16.2 1.8e-191 637.8 16.2 1.1 1 0 0 1 1 1 1 Outer membrane usher protein PapC_N PF13954.6 AIM19936.1 - 8.3e-38 129.7 0.0 2.6e-37 128.1 0.0 1.8 2 0 0 2 2 2 1 PapC N-terminal domain PapC_C PF13953.6 AIM19936.1 - 2.3e-14 52.9 0.8 1.2e-13 50.7 0.1 2.5 2 0 0 2 2 2 1 PapC C-terminal domain Big_6 PF17936.1 AIM19936.1 - 0.016 15.5 1.3 0.088 13.1 0.1 2.4 2 0 0 2 2 2 0 Bacterial Ig domain PapD_N PF00345.20 AIM19937.1 - 5.3e-37 126.5 0.4 8.1e-37 125.9 0.4 1.3 1 0 0 1 1 1 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain PapD_C PF02753.17 AIM19937.1 - 3.3e-16 59.4 0.9 1.5e-15 57.2 0.4 2.4 2 0 0 2 2 2 1 Pili assembly chaperone PapD, C-terminal domain PapG_C PF03628.13 AIM19938.1 - 8.4e-05 22.4 0.0 0.00016 21.5 0.0 1.4 1 1 0 1 1 1 1 PapG chaperone-binding domain Fimbrial PF00419.20 AIM19939.1 - 2.3e-23 83.1 0.0 1.1e-14 55.0 0.0 2.2 2 0 0 2 2 2 2 Fimbrial protein Fimbrial PF00419.20 AIM19940.1 - 6.5e-08 33.0 0.0 7.5e-08 32.8 0.0 1.0 1 0 0 1 1 1 1 Fimbrial protein Fimbrial PF00419.20 AIM19941.1 - 3.5e-07 30.6 0.0 4.3e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Fimbrial protein Fimbrial PF00419.20 AIM19942.1 - 7.6e-14 52.2 1.3 1e-13 51.8 1.3 1.2 1 0 0 1 1 1 1 Fimbrial protein Fimbrial PF00419.20 AIM19943.1 - 2.5e-09 37.6 0.1 3.1e-09 37.3 0.1 1.1 1 0 0 1 1 1 1 Fimbrial protein RE_NgoPII PF09521.10 AIM19943.1 - 0.18 10.9 0.0 0.26 10.4 0.0 1.1 1 0 0 1 1 1 0 NgoPII restriction endonuclease PapG_C PF03628.13 AIM19944.1 - 0.0018 18.1 0.2 0.0022 17.8 0.2 1.2 1 0 0 1 1 1 1 PapG chaperone-binding domain B1 PF02246.15 AIM19944.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein L b1 domain PapG_C PF03628.13 AIM19945.1 - 0.0051 16.7 1.4 0.014 15.3 1.4 1.7 1 1 0 1 1 1 1 PapG chaperone-binding domain GerE PF00196.19 AIM19946.1 - 2.3e-11 43.1 0.0 3.7e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4 PF04545.16 AIM19946.1 - 1.8e-05 24.2 0.1 3.4e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 AIM19946.1 - 0.00017 21.2 0.0 0.00032 20.3 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_28 PF13518.6 AIM19946.1 - 0.015 15.5 0.1 0.42 10.8 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_29 PF13551.6 AIM19946.1 - 0.027 14.5 0.2 0.056 13.5 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn helix HTH_23 PF13384.6 AIM19946.1 - 0.053 13.3 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Haemadin PF09065.10 AIM19947.1 - 0.67 9.8 5.4 0.13 12.1 1.6 1.8 2 0 0 2 2 2 0 Haemadin TetR_N PF00440.23 AIM19948.1 - 1.1e-05 25.1 0.0 2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_26 PF13443.6 AIM19948.1 - 0.045 14.2 0.3 0.18 12.3 0.0 2.1 2 1 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain DsbC PF11412.8 AIM19949.1 - 2.2e-34 118.1 0.1 3.7e-34 117.4 0.1 1.4 1 0 0 1 1 1 1 Disulphide bond corrector protein DsbC DsbD PF02683.15 AIM19949.1 - 2.4e-21 76.6 15.2 3.7e-21 76.0 15.2 1.3 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region Thioredoxin_7 PF13899.6 AIM19949.1 - 9.7e-14 51.3 0.1 2.6e-13 50.0 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 AIM19949.1 - 3.6e-10 40.2 0.0 7.1e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain DsbD_2 PF13386.6 AIM19949.1 - 3.4e-09 36.9 23.4 3.4e-09 36.9 23.4 2.3 2 1 1 3 3 3 1 Cytochrome C biogenesis protein transmembrane region Thioredoxin PF00085.20 AIM19949.1 - 6.5e-08 32.5 0.0 1.1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 AIM19949.1 - 0.054 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family CutA1 PF03091.15 AIM19950.1 - 8.8e-32 108.9 0.0 9.8e-32 108.8 0.0 1.0 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein DcuA_DcuB PF03605.14 AIM19951.1 - 2.1e-142 474.4 27.2 2.5e-142 474.2 27.2 1.1 1 0 0 1 1 1 1 Anaerobic c4-dicarboxylate membrane transporter DDDD PF10161.9 AIM19951.1 - 4 7.3 6.6 7.4 6.4 0.1 3.6 3 0 0 3 3 3 0 Putative mitochondrial precursor protein Lyase_1 PF00206.20 AIM19952.1 - 1.9e-109 365.9 0.0 2.2e-109 365.6 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 AIM19952.1 - 3e-18 66.0 0.2 1.7e-17 63.6 0.0 2.5 3 0 0 3 3 3 1 Fumarase C C-terminus FxsA PF04186.13 AIM19953.1 - 1.6e-32 111.8 9.1 2e-32 111.6 9.1 1.1 1 0 0 1 1 1 1 FxsA cytoplasmic membrane protein MMM1 PF10296.9 AIM19953.1 - 0.017 14.2 0.1 0.022 13.8 0.1 1.1 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 Cpn10 PF00166.21 AIM19954.1 - 8e-30 102.8 1.6 8.8e-30 102.6 1.6 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Cpn60_TCP1 PF00118.24 AIM19955.1 - 3.7e-93 312.8 20.9 5.9e-93 312.1 20.9 1.3 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family REF PF05755.12 AIM19955.1 - 0.071 12.9 0.3 0.19 11.5 0.3 1.8 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) DUF4156 PF13698.6 AIM19956.1 - 5.7e-33 113.1 0.1 6.6e-33 112.9 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4156) LPAM_1 PF08139.12 AIM19956.1 - 0.16 12.5 1.8 0.31 11.6 1.8 1.5 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Radical_SAM PF04055.21 AIM19957.1 - 1.4e-07 32.0 0.0 3.2e-07 30.9 0.0 1.6 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 AIM19957.1 - 8.2e-07 29.4 0.0 1.7e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AIM19957.1 - 1.1e-05 25.6 0.0 1.9e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Elong-fact-P_C PF09285.11 AIM19958.1 - 2e-25 88.3 0.3 5e-25 87.0 0.3 1.8 1 0 0 1 1 1 1 Elongation factor P, C-terminal EFP_N PF08207.12 AIM19958.1 - 3.1e-24 84.8 0.0 7.7e-24 83.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain EFP PF01132.20 AIM19958.1 - 4.5e-23 81.0 0.0 8.4e-23 80.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain Entericidin PF08085.11 AIM19959.1 - 1.1e-08 34.7 0.0 1.3e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Entericidin EcnA/B family BLF1 PF17752.1 AIM19959.1 - 0.16 11.3 0.0 0.16 11.2 0.0 1.0 1 0 0 1 1 1 0 Burkholderia lethal factor 1 Entericidin PF08085.11 AIM19960.1 - 6.8e-09 35.5 2.0 8.3e-09 35.2 2.0 1.1 1 0 0 1 1 1 1 Entericidin EcnA/B family Multi_Drug_Res PF00893.19 AIM19961.1 - 3.2e-32 111.1 11.9 4.3e-32 110.7 11.9 1.2 1 0 0 1 1 1 1 Small Multidrug Resistance protein EamA PF00892.20 AIM19961.1 - 0.00069 19.8 14.9 0.0014 18.8 14.9 1.5 1 1 0 1 1 1 1 EamA-like transporter family DUF5392 PF17370.2 AIM19961.1 - 0.83 9.7 3.2 0.94 9.6 2.5 1.5 1 1 1 2 2 2 0 Family of unknown function (DUF5392) FUSC PF04632.12 AIM19961.1 - 1.9 7.0 8.7 1.7 7.1 8.7 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family SLATT_6 PF18169.1 AIM19961.1 - 7.5 6.1 6.2 2.6 7.6 2.1 1.9 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 6 DUF5381 PF17353.2 AIM19961.1 - 9.9 5.9 8.2 0.73 9.6 2.3 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5381) Lipocalin_2 PF08212.12 AIM19962.1 - 5.6e-42 143.1 0.0 6.6e-42 142.9 0.0 1.0 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 AIM19962.1 - 8.4e-07 29.3 0.0 1.1e-06 29.0 0.0 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family VDE PF07137.11 AIM19962.1 - 0.15 11.5 0.0 1.1 8.8 0.0 1.9 2 0 0 2 2 2 0 VDE lipocalin domain Fumarate_red_D PF02313.17 AIM19963.1 - 4.8e-50 168.4 6.7 5.5e-50 168.3 6.7 1.0 1 0 0 1 1 1 1 Fumarate reductase subunit D Fumarate_red_C PF02300.17 AIM19964.1 - 2.7e-54 182.6 4.4 3e-54 182.5 4.4 1.0 1 0 0 1 1 1 1 Fumarate reductase subunit C Sdh_cyt PF01127.22 AIM19964.1 - 0.013 15.6 1.6 0.013 15.6 1.6 1.7 2 0 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Fer2_3 PF13085.6 AIM19965.1 - 4e-31 107.2 0.0 7.2e-31 106.4 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_8 PF13183.6 AIM19965.1 - 4.7e-12 46.2 3.1 9e-12 45.3 1.3 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AIM19965.1 - 8e-11 41.9 1.5 8e-11 41.9 1.5 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 AIM19965.1 - 5e-09 36.6 11.5 3e-07 30.9 3.2 2.4 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AIM19965.1 - 1.8e-07 31.2 3.7 0.0016 18.6 0.5 3.1 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 AIM19965.1 - 1.6e-06 28.6 2.7 1.6e-06 28.6 2.7 2.4 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.6 AIM19965.1 - 5.5e-06 26.6 0.5 0.028 14.6 0.1 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AIM19965.1 - 8.6e-06 26.6 1.1 8.6e-06 26.6 1.1 2.1 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain Fer4 PF00037.27 AIM19965.1 - 0.00036 20.2 1.4 0.00036 20.2 1.4 3.1 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_4 PF12800.7 AIM19965.1 - 0.0024 18.2 1.6 0.0024 18.2 1.6 2.7 3 0 0 3 3 2 1 4Fe-4S binding domain Fer4_21 PF14697.6 AIM19965.1 - 0.0048 17.0 7.4 0.0078 16.3 0.3 2.5 3 0 0 3 3 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 AIM19965.1 - 0.0048 16.8 0.0 0.0048 16.8 0.0 2.0 2 0 0 2 2 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_2 PF12797.7 AIM19965.1 - 0.0055 16.7 1.7 0.0055 16.7 1.7 3.4 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_6 PF12837.7 AIM19965.1 - 0.01 15.9 2.6 0.01 15.9 2.6 2.9 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_13 PF13370.6 AIM19965.1 - 0.032 14.8 0.9 0.032 14.8 0.9 2.9 3 0 0 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 AIM19965.1 - 0.11 13.5 3.7 0.11 13.5 3.7 3.0 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_15 PF13459.6 AIM19965.1 - 0.97 10.2 5.6 3.8 8.3 0.1 2.8 3 0 0 3 3 2 0 4Fe-4S single cluster domain FAD_binding_2 PF00890.24 AIM19966.1 - 4e-114 382.0 0.9 5e-114 381.6 0.9 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 AIM19966.1 - 3.7e-38 130.4 0.0 6.1e-38 129.7 0.0 1.4 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 AIM19966.1 - 1.1e-09 37.9 0.2 0.00037 19.8 0.2 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 AIM19966.1 - 0.00027 20.3 0.2 0.0012 18.1 0.1 2.1 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 AIM19966.1 - 0.00033 19.5 1.2 0.0047 15.7 0.6 2.7 2 1 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 AIM19966.1 - 0.007 15.5 0.9 0.079 12.0 0.5 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.24 AIM19966.1 - 0.012 15.2 2.7 0.032 13.8 1.6 2.4 2 1 0 2 2 2 0 FAD dependent oxidoreductase Myb_DNA-bind_4 PF13837.6 AIM19966.1 - 0.016 15.6 0.1 0.057 13.8 0.1 1.9 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Lycopene_cycl PF05834.12 AIM19966.1 - 0.016 14.3 1.6 0.023 13.8 0.4 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_oxidored PF12831.7 AIM19966.1 - 0.048 13.0 5.4 3.4 6.9 1.9 2.9 3 0 0 3 3 3 0 FAD dependent oxidoreductase GFO_IDH_MocA PF01408.22 AIM19966.1 - 0.18 12.7 0.1 0.35 11.7 0.1 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Pyr_redox_3 PF13738.6 AIM19966.1 - 2.4 7.3 5.7 2.5 7.3 2.4 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase tRNA-synt_2 PF00152.20 AIM19967.1 - 2.8e-48 164.6 0.0 4.1e-48 164.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 AIM19967.1 - 0.025 14.1 0.0 1.2 8.6 0.0 2.5 2 1 0 2 2 2 0 tRNA synthetases class II core domain (F) MscS_TM PF12794.7 AIM19968.1 - 2.2e-113 378.6 17.2 2.2e-113 378.6 17.2 2.4 2 0 0 2 2 2 1 Mechanosensitive ion channel inner membrane domain 1 MscS_porin PF12795.7 AIM19968.1 - 2.7e-57 194.1 56.9 2.7e-57 194.1 56.9 3.2 1 1 2 3 3 3 1 Mechanosensitive ion channel porin domain MS_channel PF00924.18 AIM19968.1 - 5.9e-51 172.9 0.8 1.3e-50 171.8 0.8 1.6 1 0 0 1 1 1 1 Mechanosensitive ion channel Ribosomal_L32e PF01655.18 AIM19968.1 - 0.12 12.8 0.1 0.35 11.3 0.1 1.8 1 0 0 1 1 1 0 Ribosomal protein L32 DIRP PF06584.13 AIM19968.1 - 5.9 7.1 7.7 0.61 10.3 2.1 2.3 2 0 0 2 2 2 0 DIRP PS_Dcarbxylase PF02666.15 AIM19969.1 - 4.3e-58 196.2 0.0 5.1e-58 195.9 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase RsgA_GTPase PF03193.16 AIM19970.1 - 2e-54 184.0 0.0 2.7e-54 183.5 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 AIM19970.1 - 9.9e-06 25.6 0.0 1.7e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 AIM19970.1 - 9.7e-05 22.8 0.0 0.0054 17.1 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain FeoB_N PF02421.18 AIM19970.1 - 0.00014 21.4 0.1 0.54 9.8 0.2 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B AAA_29 PF13555.6 AIM19970.1 - 0.0011 18.7 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 AIM19970.1 - 0.0029 18.1 0.2 0.05 14.1 0.0 2.3 2 0 0 2 2 2 1 ABC transporter cobW PF02492.19 AIM19970.1 - 0.0042 16.7 0.1 2.6 7.6 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 AIM19970.1 - 0.0048 16.5 0.1 0.036 13.6 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Ras PF00071.22 AIM19970.1 - 0.046 13.3 0.1 5.5 6.6 0.0 2.3 1 1 1 2 2 2 0 Ras family Pilus_CpaD PF09476.10 AIM19970.1 - 0.12 12.0 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) RNase_T PF00929.24 AIM19971.1 - 2.7e-36 125.6 0.0 3.1e-36 125.4 0.0 1.0 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 AIM19971.1 - 0.0074 16.3 0.0 0.034 14.1 0.0 1.9 1 1 0 1 1 1 1 3' exoribonuclease, RNase T-like DUF1730 PF08331.10 AIM19972.1 - 1.1e-24 86.1 0.0 3.7e-24 84.4 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1730) Fer4_16 PF13484.6 AIM19972.1 - 4.2e-19 69.2 3.4 8.1e-19 68.3 3.4 1.5 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 AIM19972.1 - 4.6e-05 23.4 2.7 0.04 14.0 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AIM19972.1 - 4.9e-05 23.4 0.8 0.012 15.8 0.1 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AIM19972.1 - 9.2e-05 23.0 6.0 0.00032 21.2 6.1 1.9 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 AIM19972.1 - 0.036 14.5 2.8 1.9 9.0 2.0 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_6 PF12837.7 AIM19972.1 - 0.13 12.4 14.4 1.4 9.1 5.1 2.8 2 2 0 2 2 2 0 4Fe-4S binding domain Fer4 PF00037.27 AIM19972.1 - 0.14 12.0 12.8 0.07 13.0 4.0 2.9 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_18 PF13746.6 AIM19972.1 - 0.52 10.5 4.4 9 6.5 1.8 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 AIM19972.1 - 0.71 10.1 10.3 11 6.2 10.3 2.2 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 AIM19972.1 - 1.2 10.2 10.0 16 6.7 4.3 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_4 PF12800.7 AIM19972.1 - 8.8 7.1 9.0 38 5.1 0.1 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Carb_kinase PF01256.17 AIM19973.1 - 1.5e-71 240.8 8.1 1.4e-70 237.5 3.5 2.2 2 0 0 2 2 2 2 Carbohydrate kinase YjeF_N PF03853.15 AIM19973.1 - 1.5e-40 138.9 0.2 1.5e-40 138.9 0.2 1.5 2 0 0 2 2 2 1 YjeF-related protein N-terminus HK PF02110.15 AIM19973.1 - 0.00045 19.7 0.3 0.00084 18.8 0.3 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TsaE PF02367.17 AIM19974.1 - 1.7e-41 141.1 0.0 2e-41 140.9 0.0 1.0 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 AIM19974.1 - 0.012 15.8 0.0 0.015 15.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 AIM19974.1 - 0.02 15.3 0.0 0.028 14.8 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 AIM19974.1 - 0.029 14.6 0.0 0.039 14.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 AIM19974.1 - 0.073 13.5 0.0 0.076 13.4 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 AIM19974.1 - 0.1 11.8 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Sigma54_activ_2 PF14532.6 AIM19974.1 - 0.11 12.6 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 AIM19974.1 - 0.15 12.0 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 AIM19974.1 - 0.21 11.5 0.0 0.26 11.1 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ATPase PF06745.13 AIM19974.1 - 0.22 10.8 0.1 0.31 10.3 0.1 1.2 1 0 0 1 1 1 0 KaiC AAA_13 PF13166.6 AIM19974.1 - 0.3 9.7 0.0 0.33 9.5 0.0 1.0 1 0 0 1 1 1 0 AAA domain Amidase_3 PF01520.18 AIM19975.1 - 4.3e-48 163.7 0.0 6.9e-48 163.1 0.0 1.3 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase LysM PF01476.20 AIM19975.1 - 7.2e-26 90.0 0.0 4.5e-12 45.8 0.0 2.7 2 0 0 2 2 2 2 LysM domain AMIN PF11741.8 AIM19975.1 - 6.3e-07 29.4 0.1 1.7e-06 28.1 0.1 1.7 1 0 0 1 1 1 1 AMIN domain DNA_mis_repair PF01119.19 AIM19976.1 - 5.2e-39 132.6 0.0 8.6e-39 131.9 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.11 AIM19976.1 - 3.7e-26 91.6 0.6 7.3e-26 90.7 0.6 1.5 1 0 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.6 AIM19976.1 - 1.1e-12 48.0 0.0 1.9e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 AIM19976.1 - 3e-07 30.9 0.0 6.6e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IPPT PF01715.17 AIM19977.1 - 2.8e-51 174.5 0.0 3.1e-51 174.4 0.0 1.0 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 AIM19977.1 - 7.1e-05 22.3 0.0 8.6e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Isopentenyl transferase AAA_33 PF13671.6 AIM19977.1 - 0.00063 19.9 0.0 0.0013 18.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 AIM19977.1 - 0.1 12.3 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase Hfq PF17209.3 AIM19978.1 - 4.1e-31 106.4 0.1 5.1e-31 106.1 0.1 1.1 1 0 0 1 1 1 1 Hfq protein LSM PF01423.22 AIM19978.1 - 0.0029 17.3 0.0 0.0038 16.9 0.0 1.3 1 0 0 1 1 1 1 LSM domain GTP-bdg_N PF13167.6 AIM19979.1 - 1.3e-31 109.1 0.0 3.8e-31 107.6 0.0 1.8 1 0 0 1 1 1 1 GTP-binding GTPase N-terminal GTP-bdg_M PF16360.5 AIM19979.1 - 9.8e-29 99.8 11.0 2e-28 98.8 11.0 1.6 1 0 0 1 1 1 1 GTP-binding GTPase Middle Region MMR_HSR1 PF01926.23 AIM19979.1 - 4.4e-21 75.1 0.0 1.6e-20 73.3 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 AIM19979.1 - 9.9e-06 25.5 0.0 0.19 11.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 AIM19979.1 - 1.2e-05 24.9 0.0 2.1e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 AIM19979.1 - 0.00028 20.4 0.5 0.0028 17.1 0.5 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 AIM19979.1 - 0.00038 20.1 0.0 0.2 11.2 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 AIM19979.1 - 0.0041 17.2 0.2 0.23 11.5 0.0 2.4 1 1 1 2 2 2 1 Dynamin family Roc PF08477.13 AIM19979.1 - 0.0098 16.1 0.0 1.4 9.1 0.0 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 AIM19979.1 - 0.022 14.2 0.1 0.044 13.2 0.1 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit cobW PF02492.19 AIM19979.1 - 0.024 14.2 1.6 1.3 8.6 0.2 2.4 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TniB PF05621.11 AIM19979.1 - 0.029 13.8 0.0 0.052 13.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA PF00004.29 AIM19979.1 - 0.04 14.3 0.0 0.16 12.4 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 AIM19979.1 - 0.061 13.8 0.0 0.31 11.6 0.0 2.1 2 0 0 2 2 2 0 ABC transporter ATP_bind_1 PF03029.17 AIM19979.1 - 0.09 12.5 0.5 0.29 10.9 0.2 1.7 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein MMR_HSR1_Xtn PF16897.5 AIM19979.1 - 0.11 12.5 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Band_7 PF01145.25 AIM19980.1 - 9.2e-28 97.4 1.4 1.3e-27 97.0 1.4 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family HflK_N PF12221.8 AIM19980.1 - 6.2e-15 54.9 13.6 1.5e-14 53.7 13.6 1.7 1 0 0 1 1 1 1 Bacterial membrane protein N terminal Nitrophorin PF02087.15 AIM19980.1 - 0.14 12.1 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 Nitrophorin Band_7 PF01145.25 AIM19981.1 - 5e-34 117.8 0.6 5e-34 117.8 0.6 1.6 1 1 1 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 AIM19981.1 - 0.066 12.9 0.1 0.27 10.9 0.0 2.0 2 0 0 2 2 2 0 SPFH domain-Band 7 family CCP_MauG PF03150.14 AIM19981.1 - 0.2 12.3 1.5 0.5 11.0 1.5 1.7 1 1 0 1 1 1 0 Di-haem cytochrome c peroxidase 5_3_exonuc_N PF02739.16 AIM19981.1 - 0.23 11.4 2.0 3.7 7.4 0.1 2.7 3 0 0 3 3 3 0 5'-3' exonuclease, N-terminal resolvase-like domain DUF2065 PF09838.9 AIM19982.1 - 3.6e-22 78.1 6.6 4e-22 78.0 6.6 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2065) Adenylsucc_synt PF00709.21 AIM19983.1 - 9.4e-179 594.7 0.1 1.1e-178 594.5 0.1 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Rrf2 PF02082.20 AIM19984.1 - 1.1e-25 89.7 0.1 1.7e-25 89.2 0.1 1.3 1 0 0 1 1 1 1 Transcriptional regulator TrmB PF01978.19 AIM19984.1 - 5e-05 23.1 0.0 0.002 18.0 0.0 2.2 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB SgrR_N PF12793.7 AIM19984.1 - 0.011 15.9 0.0 0.15 12.3 0.0 2.0 2 0 0 2 2 2 0 Sugar transport-related sRNA regulator N-term HTH_27 PF13463.6 AIM19984.1 - 0.014 15.8 0.0 0.042 14.3 0.0 1.8 2 0 0 2 2 2 0 Winged helix DNA-binding domain GntR PF00392.21 AIM19984.1 - 0.061 13.0 0.0 0.17 11.6 0.0 1.6 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_20 PF12840.7 AIM19984.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_36 PF13730.6 AIM19984.1 - 0.17 11.9 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain RNB PF00773.19 AIM19985.1 - 1.3e-105 353.3 0.0 1.9e-105 352.8 0.0 1.2 1 0 0 1 1 1 1 RNB domain CSD2 PF17876.1 AIM19985.1 - 2.5e-27 94.8 0.1 5.1e-23 81.0 0.0 2.5 2 0 0 2 2 2 2 Cold shock domain OB_RNB PF08206.11 AIM19985.1 - 6.8e-26 89.7 10.4 3.6e-21 74.6 0.2 4.0 4 0 0 4 4 4 2 Ribonuclease B OB domain S1 PF00575.23 AIM19985.1 - 2.1e-16 60.0 0.2 5.1e-16 58.8 0.2 1.6 1 0 0 1 1 1 1 S1 RNA binding domain HTH_12 PF08461.10 AIM19985.1 - 1.6e-15 56.8 0.8 3.9e-15 55.5 0.8 1.7 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain Rho_RNA_bind PF07497.12 AIM19985.1 - 0.033 14.0 0.1 0.1 12.5 0.1 1.8 1 0 0 1 1 1 0 Rho termination factor, RNA-binding domain RNA_pol_Rbc25 PF08292.12 AIM19985.1 - 0.034 14.4 0.5 0.095 12.9 0.0 1.9 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 OB_Dis3 PF17849.1 AIM19985.1 - 0.051 13.6 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Dis3-like cold-shock domain 2 (CSD2) RNase_II_C_S1 PF18614.1 AIM19985.1 - 0.075 13.0 0.1 0.58 10.1 0.0 2.5 3 0 0 3 3 3 0 RNase II-type exonuclease C-terminal S1 domain SpoU_methylase PF00588.19 AIM19986.1 - 2.9e-40 137.7 0.1 5.3e-40 136.9 0.0 1.4 2 0 0 2 2 2 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 AIM19986.1 - 2.9e-20 72.3 0.1 2.2e-19 69.5 0.1 2.0 2 0 0 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding AidB_N PF18158.1 AIM19987.1 - 2.7e-56 189.8 0.1 1e-55 188.0 0.0 2.0 2 0 0 2 2 2 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_1 PF00441.24 AIM19987.1 - 1.6e-29 103.0 1.0 2.4e-29 102.5 0.1 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 AIM19987.1 - 7.6e-14 51.7 0.0 1.2e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 AIM19987.1 - 4e-06 27.1 0.0 1.1e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain TolA_bind_tri PF16331.5 AIM19987.1 - 0.03 14.4 0.9 0.03 14.4 0.9 1.8 2 0 0 2 2 2 0 TolA binding protein trimerisation DUF350 PF03994.14 AIM19988.1 - 2.9e-19 68.9 5.2 3.9e-11 42.9 0.4 2.1 2 0 0 2 2 2 2 Domain of Unknown Function (DUF350) VIT1 PF01988.19 AIM19988.1 - 0.0019 18.1 2.4 0.0019 18.1 2.4 2.0 1 1 1 2 2 2 1 VIT family EI24 PF07264.11 AIM19988.1 - 0.014 15.6 3.6 0.023 15.0 3.6 1.3 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) Keratin_assoc PF09775.9 AIM19988.1 - 0.08 12.6 1.5 0.69 9.6 1.2 2.0 1 1 0 1 1 1 0 Keratinocyte-associated protein 2 DUF1471 PF07338.13 AIM19989.1 - 9e-13 48.0 0.0 1.5e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1471) DUF1471 PF07338.13 AIM19990.1 - 1.5e-18 66.5 0.1 2.1e-18 66.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1471) DUF1627 PF07789.12 AIM19990.1 - 0.12 12.0 0.8 0.15 11.7 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1627) Tom5 PF10642.9 AIM19990.1 - 0.13 12.3 1.5 0.21 11.7 0.8 1.6 1 1 0 1 1 1 0 Mitochondrial import receptor subunit or translocase Hydrolase_4 PF12146.8 AIM19991.1 - 6.5e-12 45.2 0.2 1.7e-07 30.8 0.1 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 AIM19991.1 - 2.1e-10 40.4 0.0 3.1e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 AIM19991.1 - 4.8e-08 32.9 0.2 3.9e-05 23.4 0.3 2.7 1 1 0 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 AIM19991.1 - 1.1e-06 28.3 0.0 3.6e-06 26.7 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 AIM19991.1 - 0.00013 22.7 10.0 0.00024 21.8 10.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 AIM19991.1 - 0.001 18.9 0.0 1.5 8.6 0.0 3.0 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.7 AIM19991.1 - 0.0036 16.2 0.0 0.0054 15.7 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Esterase PF00756.20 AIM19991.1 - 0.0059 16.3 0.0 0.0073 16.0 0.0 1.3 1 0 0 1 1 1 1 Putative esterase BAAT_C PF08840.11 AIM19991.1 - 0.0065 16.4 0.0 0.044 13.7 0.0 1.9 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal PAF-AH_p_II PF03403.13 AIM19991.1 - 0.075 11.5 0.6 0.31 9.5 0.1 1.8 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II FSH1 PF03959.13 AIM19991.1 - 0.18 11.4 0.0 3 7.4 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Chlorophyllase PF07224.11 AIM19991.1 - 0.21 10.6 0.0 0.29 10.1 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase Peptidase_S15 PF02129.18 AIM19991.1 - 0.27 10.8 0.9 1 8.9 0.3 2.0 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) GIT1_C PF12205.8 AIM19992.1 - 0.038 14.1 0.2 0.047 13.8 0.2 1.2 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term DUF1471 PF07338.13 AIM19993.1 - 1e-18 67.1 0.1 2e-18 66.1 0.0 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF1471) Ribosomal_S6 PF01250.17 AIM19994.1 - 7.1e-28 96.7 0.1 9.3e-28 96.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 DUF2313 PF10076.9 AIM19994.1 - 0.015 15.2 0.0 0.19 11.6 0.0 2.0 1 1 1 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2313) SSB PF00436.25 AIM19995.1 - 3.4e-14 52.7 0.0 3.6e-14 52.7 0.0 1.0 1 0 0 1 1 1 1 Single-strand binding protein family tRNA_anti-codon PF01336.25 AIM19995.1 - 0.0038 17.2 0.0 0.0041 17.1 0.0 1.2 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 AIM19995.1 - 0.0067 16.6 0.0 0.0084 16.3 0.0 1.2 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Ribosomal_S18 PF01084.20 AIM19996.1 - 7.5e-25 86.9 0.5 9.8e-25 86.5 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S18 Ribosomal_L9_C PF03948.14 AIM19997.1 - 1.2e-24 86.6 0.7 1.8e-24 86.0 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L9, C-terminal domain Ribosomal_L9_N PF01281.19 AIM19997.1 - 3.6e-22 77.7 0.4 6.6e-22 76.8 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Tautomerase PF01361.21 AIM19997.1 - 0.35 10.8 2.3 8.5 6.4 0.1 2.3 2 0 0 2 2 2 0 Tautomerase enzyme DUF488 PF04343.13 AIM19998.1 - 1.4e-26 93.5 0.2 1.6e-26 93.3 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF488 OapA PF04225.12 AIM19999.1 - 1.7e-32 111.3 0.1 2.3e-32 110.9 0.1 1.2 1 0 0 1 1 1 1 Opacity-associated protein A LysM-like domain OapA_N PF08525.11 AIM19999.1 - 7.2e-07 29.0 4.2 1.2e-06 28.2 4.2 1.4 1 0 0 1 1 1 1 Opacity-associated protein A N-terminal motif FKBP_C PF00254.28 AIM20000.1 - 3.4e-26 91.4 0.0 6.2e-26 90.6 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N PF01346.18 AIM20000.1 - 5.6e-19 68.9 0.0 7e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase 5_nucleotid_C PF02872.18 AIM20001.1 - 5.8e-22 78.6 0.2 1.6e-21 77.2 0.1 1.8 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 AIM20001.1 - 4.2e-09 37.2 0.0 7.5e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Inositol_P PF00459.25 AIM20002.1 - 4.3e-47 160.9 0.0 5.3e-47 160.6 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Phosphonate-bd PF12974.7 AIM20002.1 - 0.04 13.5 0.0 0.061 12.9 0.0 1.2 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein YtfJ_HI0045 PF09695.10 AIM20003.1 - 4e-77 257.3 0.3 4.5e-77 257.2 0.3 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (YtfJ_HI0045) VWA_3 PF13768.6 AIM20003.1 - 0.056 13.4 0.0 0.25 11.3 0.0 1.9 2 0 0 2 2 2 0 von Willebrand factor type A domain ATP-synt_10 PF05176.14 AIM20003.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.3 1 1 0 1 1 1 0 ATP10 protein DUF1107 PF06526.12 AIM20004.1 - 1.3e-29 101.9 0.2 1.4e-29 101.8 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1107) DUF21 PF01595.20 AIM20005.1 - 9.1e-38 129.7 5.3 1.5e-37 129.0 5.3 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CorC_HlyC PF03471.17 AIM20005.1 - 6.6e-21 74.1 0.0 1.7e-20 72.8 0.0 1.7 1 0 0 1 1 1 1 Transporter associated domain CBS PF00571.28 AIM20005.1 - 2.5e-06 27.9 1.0 0.0032 17.9 0.1 3.1 3 0 0 3 3 3 2 CBS domain PMSR PF01625.21 AIM20006.1 - 2.5e-67 225.8 0.5 3e-67 225.6 0.5 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Metal_resist PF13801.6 AIM20006.1 - 0.0062 16.7 0.9 0.01 16.0 0.9 1.2 1 0 0 1 1 1 1 Heavy-metal resistance Gln-synt_C PF00120.24 AIM20006.1 - 0.053 12.5 0.0 1.2 8.1 0.0 2.0 1 1 1 2 2 2 0 Glutamine synthetase, catalytic domain Bac_surface_Ag PF01103.23 AIM20007.1 - 1.4e-31 110.2 5.9 4.3e-31 108.6 5.9 1.7 1 1 0 1 1 1 1 Surface antigen POTRA_TamA_1 PF17243.2 AIM20007.1 - 8.2e-21 73.9 0.0 1.5e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 POTRA domain TamA domain 1 POTRA PF07244.15 AIM20007.1 - 8.4e-14 51.9 0.1 6.2e-08 33.1 0.0 3.6 3 0 0 3 3 3 2 Surface antigen variable number repeat TraW_N PF12477.8 AIM20007.1 - 0.65 10.0 2.0 1.2 9.1 2.0 1.4 1 0 0 1 1 1 0 Sex factor F TraW protein N terminal TamB PF04357.13 AIM20008.1 - 4.1e-73 246.8 15.1 2.8e-68 230.9 0.7 5.3 4 3 1 5 5 5 5 TamB, inner membrane protein subunit of TAM complex Bactofilin PF04519.13 AIM20008.1 - 0.002 18.4 0.8 0.22 11.8 0.1 3.8 3 0 0 3 3 3 1 Polymer-forming cytoskeletal AsmA_2 PF13502.6 AIM20008.1 - 0.016 14.8 0.4 0.016 14.8 0.4 6.0 2 2 4 6 6 6 0 AsmA-like C-terminal region GGACT PF06094.12 AIM20009.1 - 2.8e-22 79.6 0.1 3.2e-22 79.4 0.1 1.0 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Pyrophosphatase PF00719.19 AIM20010.1 - 5.4e-55 185.6 0.0 6.1e-55 185.4 0.0 1.0 1 0 0 1 1 1 1 Inorganic pyrophosphatase InPase PF18823.1 AIM20010.1 - 0.036 13.8 0.0 0.081 12.6 0.0 1.5 2 0 0 2 2 2 0 Inorganic Pyrophosphatase MCPsignal PF00015.21 AIM20011.1 - 2.7e-53 180.3 32.7 9.2e-53 178.6 20.7 2.6 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain TarH PF02203.15 AIM20011.1 - 3e-21 76.1 1.2 3e-21 76.1 1.2 4.5 5 0 0 5 5 5 1 Tar ligand binding domain homologue HAMP PF00672.25 AIM20011.1 - 2.6e-07 30.9 1.2 2.6e-07 30.9 1.2 3.7 4 0 0 4 4 4 1 HAMP domain 4HB_MCP_1 PF12729.7 AIM20011.1 - 0.00079 19.0 1.2 0.00079 19.0 1.2 3.6 3 2 1 4 4 4 1 Four helix bundle sensory module for signal transduction DUF948 PF06103.11 AIM20011.1 - 0.31 11.3 21.8 0.77 10.1 0.2 4.9 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF948) BLOC1_2 PF10046.9 AIM20011.1 - 0.36 11.1 15.8 4.8 7.6 3.1 4.5 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 AIM20011.1 - 0.59 10.2 16.3 1.7 8.7 4.4 4.0 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) ExbD PF02472.16 AIM20011.1 - 0.62 10.2 0.0 0.62 10.2 0.0 3.0 4 0 0 4 4 4 0 Biopolymer transport protein ExbD/TolR Adaptin_binding PF10199.9 AIM20011.1 - 0.9 10.2 8.1 0.64 10.6 1.7 3.0 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 SAM_KSR1 PF13543.6 AIM20011.1 - 5.5 7.2 8.2 1.3 9.2 0.8 3.3 4 0 0 4 4 4 0 SAM like domain present in kinase suppressor RAS 1 FBPase PF00316.20 AIM20012.1 - 8.8e-81 269.9 0.2 1.1e-80 269.6 0.2 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 AIM20012.1 - 0.056 13.0 0.0 0.099 12.1 0.0 1.3 1 0 0 1 1 1 0 Inositol monophosphatase family Mur_ligase PF01225.25 AIM20013.1 - 2.6e-19 69.3 0.0 5.1e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 Mur ligase family, catalytic domain Mur_ligase_M PF08245.12 AIM20013.1 - 2.5e-18 66.8 0.0 3.4e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 AIM20013.1 - 7.8e-10 38.9 0.0 2.5e-09 37.3 0.0 1.9 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain DUF1471 PF07338.13 AIM20014.1 - 1.6e-22 79.3 0.8 2.4e-22 78.7 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1471) DUF1471 PF07338.13 AIM20015.1 - 1.6e-22 79.2 0.7 2.3e-22 78.7 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1471) Arg_repressor PF01316.21 AIM20016.1 - 7.2e-25 86.5 0.1 1.1e-24 86.0 0.1 1.3 1 0 0 1 1 1 1 Arginine repressor, DNA binding domain Arg_repressor_C PF02863.18 AIM20016.1 - 6.8e-24 83.5 0.1 1.2e-23 82.7 0.1 1.3 1 0 0 1 1 1 1 Arginine repressor, C-terminal domain DUF4911 PF16256.5 AIM20016.1 - 0.13 12.3 0.0 0.33 10.9 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4911) Ldh_1_C PF02866.18 AIM20017.1 - 7e-52 175.7 0.0 1e-51 175.2 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 AIM20017.1 - 3.6e-46 156.8 0.6 5.2e-46 156.2 0.6 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 AIM20017.1 - 0.14 12.6 0.6 0.4 11.1 0.1 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain HTH_35 PF13693.6 AIM20018.1 - 1.5e-37 127.5 0.2 1.7e-37 127.3 0.2 1.0 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_38 PF13936.6 AIM20018.1 - 0.001 18.8 0.4 0.0066 16.2 0.2 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_28 PF13518.6 AIM20018.1 - 0.0023 18.0 0.1 0.019 15.1 0.1 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 AIM20018.1 - 0.0033 17.5 0.3 0.13 12.3 0.3 2.1 2 0 0 2 2 2 1 Helix-turn-helix HTH_IclR PF09339.10 AIM20018.1 - 0.023 14.5 1.0 0.12 12.1 0.6 2.0 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_8 PF02954.19 AIM20018.1 - 0.024 14.4 0.5 0.13 12.1 1.0 1.7 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family HTH_23 PF13384.6 AIM20018.1 - 0.025 14.4 0.1 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 AIM20018.1 - 0.025 14.0 0.3 0.25 10.8 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_AsnC-type PF13404.6 AIM20018.1 - 0.034 14.0 0.3 1.7 8.5 0.6 2.4 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain DprA_WH PF17782.1 AIM20018.1 - 0.044 13.9 0.0 0.073 13.2 0.0 1.3 1 0 0 1 1 1 0 DprA winged helix domain HTH_24 PF13412.6 AIM20018.1 - 0.083 12.5 0.4 0.33 10.6 0.3 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding DUF1323 PF07037.11 AIM20019.1 - 1.7e-09 38.1 0.4 2.8e-08 34.2 0.4 2.0 1 1 0 1 1 1 1 Putative transcription regulator (DUF1323) HTH_Tnp_Mu_1 PF02316.16 AIM20019.1 - 1.7e-09 38.0 0.0 3e-09 37.2 0.0 1.4 1 1 0 1 1 1 1 Mu DNA-binding domain polyprenyl_synt PF00348.17 AIM20020.1 - 5.5e-76 255.0 0.2 6.9e-76 254.7 0.2 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase MRP-63 PF14978.6 AIM20020.1 - 0.07 13.8 0.0 0.14 12.8 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosome protein 63 DUF2291 PF10054.9 AIM20020.1 - 0.12 12.0 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Predicted periplasmic lipoprotein (DUF2291) DUF2249 PF10006.9 AIM20020.1 - 0.16 11.9 0.2 0.79 9.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2249) Ribosomal_L21p PF00829.21 AIM20021.1 - 1.6e-37 127.8 2.4 1.8e-37 127.6 2.4 1.0 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Ribosomal_L27 PF01016.19 AIM20022.1 - 4.9e-39 132.2 2.7 5.4e-39 132.1 2.7 1.0 1 0 0 1 1 1 1 Ribosomal L27 protein EamA PF00892.20 AIM20023.1 - 2.5e-41 141.1 39.1 8.8e-26 90.7 14.4 2.6 2 1 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 AIM20023.1 - 0.00031 19.8 4.8 0.0005 19.1 2.6 2.1 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like DUF3493 PF11998.8 AIM20023.1 - 6.9 6.9 8.0 0.48 10.6 0.2 3.0 4 0 0 4 4 4 0 Low psii accumulation1 / Rep27 GTP1_OBG PF01018.22 AIM20024.1 - 1.2e-59 200.4 3.0 1.7e-59 199.8 3.0 1.2 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 AIM20024.1 - 1.6e-24 86.2 0.0 2.4e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AIM20024.1 - 1.3e-07 31.2 0.0 3.2e-07 30.0 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 AIM20024.1 - 0.0015 17.6 2.1 0.96 8.4 0.1 2.6 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB Gtr1_RagA PF04670.12 AIM20024.1 - 0.053 12.9 0.0 0.08 12.3 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 AIM20024.1 - 0.073 13.0 0.0 0.42 10.5 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase HATPase_c PF02518.26 AIM20025.1 - 2.6e-18 66.6 0.0 4.2e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AIM20025.1 - 2.2e-09 37.2 2.0 6.7e-09 35.7 1.2 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AIM20025.1 - 9.6e-07 29.1 1.2 5.4e-05 23.5 0.0 3.2 3 0 0 3 3 3 1 HAMP domain HATPase_c_2 PF13581.6 AIM20025.1 - 0.035 14.1 0.0 0.076 13.0 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Med15_fungi PF05397.12 AIM20025.1 - 1.4 9.2 4.5 1.2 9.4 0.2 2.8 3 0 0 3 3 3 0 Mediator complex subunit 15 Response_reg PF00072.24 AIM20026.1 - 1.4e-25 89.6 0.3 3e-25 88.6 0.1 1.6 2 0 0 2 2 2 1 Response regulator receiver domain Trans_reg_C PF00486.28 AIM20026.1 - 1e-20 73.6 0.6 2.5e-20 72.3 0.3 1.8 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal DUF1598 PF07643.11 AIM20026.1 - 0.12 12.6 1.1 4.6 7.5 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1598) Peptidase_S13 PF02113.15 AIM20027.1 - 9.1e-166 552.0 0.0 1.1e-165 551.8 0.0 1.0 1 0 0 1 1 1 1 D-Ala-D-Ala carboxypeptidase 3 (S13) family Beta-lactamase2 PF13354.6 AIM20027.1 - 8.9e-07 28.7 0.5 4.6e-05 23.1 0.1 3.0 2 2 0 2 2 2 1 Beta-lactamase enzyme family Transpeptidase PF00905.22 AIM20027.1 - 0.12 11.5 0.5 0.53 9.4 0.0 2.1 3 0 0 3 3 3 0 Penicillin binding protein transpeptidase domain GreA_GreB_N PF03449.15 AIM20028.1 - 2.6e-32 110.8 1.2 3.7e-32 110.3 1.2 1.2 1 0 0 1 1 1 1 Transcription elongation factor, N-terminal GreA_GreB PF01272.19 AIM20028.1 - 3.3e-29 100.6 0.3 4.7e-29 100.1 0.3 1.2 1 0 0 1 1 1 1 Transcription elongation factor, GreA/GreB, C-term DDR_swiveling PF18427.1 AIM20028.1 - 0.0079 16.2 0.2 0.048 13.7 0.1 2.0 1 1 1 2 2 2 1 DD-reactivating factor swiveling domain Inhibitor_I24 PF10465.9 AIM20028.1 - 0.022 14.8 0.1 0.028 14.4 0.1 1.3 1 0 0 1 1 1 0 PinA peptidase inhibitor CRS1_YhbY PF01985.21 AIM20029.1 - 4.8e-23 81.1 0.4 5.6e-23 80.9 0.4 1.0 1 0 0 1 1 1 1 CRS1 / YhbY (CRM) domain FtsJ PF01728.19 AIM20030.1 - 4.1e-57 193.1 0.0 5e-57 192.8 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 AIM20030.1 - 0.018 15.8 1.1 1.1 10.0 0.5 3.1 2 1 1 3 3 3 0 Methyltransferase domain Methyltr_RsmB-F PF01189.17 AIM20030.1 - 0.086 12.5 0.0 0.25 10.9 0.0 1.8 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F Reovirus_L2 PF06016.11 AIM20030.1 - 0.22 8.7 0.0 0.26 8.5 0.0 1.0 1 0 0 1 1 1 0 Reovirus core-spike protein lambda-2 (L2) Peptidase_M41 PF01434.18 AIM20031.1 - 7.6e-73 244.4 0.2 1.3e-72 243.6 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 AIM20031.1 - 2.2e-46 157.6 0.0 6.9e-46 155.9 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.15 AIM20031.1 - 1.9e-16 60.4 0.2 6.8e-16 58.6 0.1 2.0 2 0 0 2 2 2 1 FtsH Extracellular AAA_lid_3 PF17862.1 AIM20031.1 - 8.2e-12 44.7 0.0 1.6e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 AIM20031.1 - 3.1e-06 27.2 0.0 1.6e-05 25.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 AIM20031.1 - 1.6e-05 24.3 0.0 3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 AIM20031.1 - 0.00018 21.3 0.0 0.00082 19.1 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 AIM20031.1 - 0.00051 20.5 0.3 0.028 14.8 0.1 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_33 PF13671.6 AIM20031.1 - 0.0019 18.3 0.0 0.0047 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 AIM20031.1 - 0.0025 17.9 0.1 0.018 15.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 AIM20031.1 - 0.0034 16.8 0.2 0.0096 15.3 0.2 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 AIM20031.1 - 0.0038 17.0 0.0 0.0088 15.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 AIM20031.1 - 0.0081 16.4 0.1 0.2 11.9 0.1 2.6 1 1 1 2 2 2 1 AAA domain CSTF2_hinge PF14327.6 AIM20031.1 - 0.012 16.1 0.1 0.029 14.8 0.1 1.7 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 ABC_tran PF00005.27 AIM20031.1 - 0.014 16.0 0.9 0.23 12.0 0.1 2.8 3 0 0 3 3 3 0 ABC transporter Sigma54_activat PF00158.26 AIM20031.1 - 0.035 13.8 0.1 0.29 10.8 0.0 2.4 2 1 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 AIM20031.1 - 0.045 13.0 0.1 0.11 11.7 0.1 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_7 PF12775.7 AIM20031.1 - 0.076 12.5 0.2 0.22 11.0 0.2 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_PrkA PF08298.11 AIM20031.1 - 0.089 11.7 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain PhoH PF02562.16 AIM20031.1 - 0.1 12.0 0.3 0.24 10.8 0.3 1.5 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activ_2 PF14532.6 AIM20031.1 - 0.12 12.5 0.0 0.34 11.0 0.0 1.7 2 0 0 2 2 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 AIM20031.1 - 0.12 12.0 0.0 0.42 10.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 AIM20031.1 - 0.13 12.3 0.0 0.37 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 AIM20031.1 - 0.15 12.3 0.0 0.37 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Pterin_bind PF00809.22 AIM20032.1 - 2.4e-87 292.7 0.0 2.8e-87 292.4 0.0 1.0 1 0 0 1 1 1 1 Pterin binding enzyme PGM_PMM_I PF02878.16 AIM20033.1 - 3.3e-45 153.2 0.0 7.5e-45 152.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 AIM20033.1 - 7.9e-31 106.6 0.1 1.4e-30 105.8 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 AIM20033.1 - 3.4e-19 69.4 0.0 8.6e-19 68.1 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 AIM20033.1 - 1e-16 60.9 1.0 2.7e-16 59.5 1.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF384 PF04064.13 AIM20033.1 - 0.18 11.7 0.3 0.44 10.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF384) SecG PF03840.14 AIM20034.1 - 4.8e-22 77.8 11.9 6.8e-22 77.3 11.9 1.2 1 0 0 1 1 1 1 Preprotein translocase SecG subunit PulG PF11773.8 AIM20034.1 - 0.023 14.5 0.4 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 Type II secretory pathway pseudopilin DUF150 PF02576.17 AIM20035.1 - 2.5e-29 101.5 0.4 4.6e-29 100.6 0.1 1.6 2 1 1 3 3 3 1 RimP N-terminal domain DUF150_C PF17384.2 AIM20035.1 - 3.4e-22 78.4 0.0 5.1e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 RimP C-terminal SH3 domain RACo_linker PF17650.1 AIM20035.1 - 0.074 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 RACo linker region NusA_N PF08529.11 AIM20036.1 - 1.1e-36 125.8 5.3 2.9e-36 124.5 5.3 1.8 1 0 0 1 1 1 1 NusA N-terminal domain KH_5 PF13184.6 AIM20036.1 - 2e-30 104.6 0.4 9.8e-28 96.1 0.2 2.7 2 0 0 2 2 2 2 NusA-like KH domain HHH_5 PF14520.6 AIM20036.1 - 5.3e-18 65.4 1.3 1.3e-10 41.7 0.1 3.0 2 0 0 2 2 2 2 Helix-hairpin-helix domain S1 PF00575.23 AIM20036.1 - 0.00019 21.7 0.1 0.00073 19.8 0.1 2.1 1 0 0 1 1 1 1 S1 RNA binding domain DUF4332 PF14229.6 AIM20036.1 - 0.0009 19.5 0.2 0.67 10.2 0.1 2.7 1 1 1 2 2 2 2 Domain of unknown function (DUF4332) KH_4 PF13083.6 AIM20036.1 - 0.046 13.6 1.1 0.24 11.3 0.0 2.8 4 0 0 4 4 4 0 KH domain KH_2 PF07650.17 AIM20036.1 - 0.072 12.9 3.2 0.14 12.0 0.0 2.9 3 0 0 3 3 3 0 KH domain HHH_3 PF12836.7 AIM20036.1 - 0.11 12.8 0.1 15 5.9 0.0 3.5 2 1 1 3 3 3 0 Helix-hairpin-helix motif IF-2 PF11987.8 AIM20037.1 - 1.5e-36 124.7 0.7 5.2e-36 122.9 0.7 2.1 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU PF00009.27 AIM20037.1 - 3.6e-35 121.3 1.7 3.6e-35 121.3 1.7 3.4 3 2 0 3 3 2 1 Elongation factor Tu GTP binding domain IF2_N PF04760.15 AIM20037.1 - 4.7e-25 87.2 5.3 1.6e-14 53.5 1.5 3.2 3 0 0 3 3 3 2 Translation initiation factor IF-2, N-terminal region IF2_assoc PF08364.11 AIM20037.1 - 4.5e-16 58.8 5.1 4.5e-16 58.8 5.1 2.4 2 0 0 2 2 2 1 Bacterial translation initiation factor IF-2 associated region GTP_EFTU_D2 PF03144.25 AIM20037.1 - 6.5e-10 39.3 2.2 8.6e-07 29.3 0.4 3.0 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 AIM20037.1 - 8.1e-10 38.8 0.1 2.8e-09 37.1 0.1 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 AIM20037.1 - 2.4e-06 27.3 0.9 6.1e-06 25.9 0.0 2.2 2 0 0 2 2 2 1 Ras family Arf PF00025.21 AIM20037.1 - 1.5e-05 24.6 0.0 4e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.18 AIM20037.1 - 6.9e-05 22.4 0.0 0.00018 21.0 0.0 1.8 1 0 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.9 AIM20037.1 - 0.0024 17.6 0.0 0.0085 15.8 0.0 2.0 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1_Xtn PF16897.5 AIM20037.1 - 0.0036 17.3 0.1 0.029 14.4 0.0 2.4 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain SRPRB PF09439.10 AIM20037.1 - 0.0049 16.3 0.0 0.0049 16.3 0.0 2.3 2 1 0 2 2 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 AIM20037.1 - 0.0082 16.4 0.0 0.023 14.9 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU_D4 PF14578.6 AIM20037.1 - 0.09 12.7 1.5 0.35 10.8 0.2 2.8 2 1 1 3 3 2 0 Elongation factor Tu domain 4 RBFA PF02033.18 AIM20038.1 - 1.6e-30 105.7 0.0 1.9e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 Ribosome-binding factor A TruB_N PF01509.18 AIM20039.1 - 2.9e-59 199.7 0.0 4.1e-59 199.2 0.0 1.2 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 AIM20039.1 - 8.5e-23 80.3 0.1 1.6e-22 79.4 0.1 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB-C_2 PF09157.11 AIM20039.1 - 3.3e-20 71.9 1.4 1e-19 70.3 1.4 1.9 1 0 0 1 1 1 1 Pseudouridine synthase II TruB, C-terminal Ribosomal_S15 PF00312.22 AIM20040.1 - 1.6e-37 127.6 0.9 1.8e-37 127.4 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S15 RNase_PH PF01138.21 AIM20041.1 - 6.6e-43 146.4 0.0 2.8e-21 76.4 0.0 2.4 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 PNPase PF03726.14 AIM20041.1 - 1.4e-25 89.6 1.5 1.4e-25 89.6 1.5 2.1 2 0 0 2 2 2 1 Polyribonucleotide nucleotidyltransferase, RNA binding domain S1 PF00575.23 AIM20041.1 - 7.4e-23 80.7 7.8 1.1e-22 80.1 3.5 3.1 3 0 0 3 3 3 1 S1 RNA binding domain RNase_PH_C PF03725.15 AIM20041.1 - 8.2e-22 77.0 1.3 1.2e-13 50.8 0.0 2.6 2 0 0 2 2 2 2 3' exoribonuclease family, domain 2 KH_1 PF00013.29 AIM20041.1 - 2.6e-08 33.5 2.6 2.6e-08 33.5 2.6 2.2 2 0 0 2 2 2 1 KH domain S1_2 PF13509.6 AIM20041.1 - 0.0015 18.6 0.3 0.0059 16.6 0.0 2.3 2 1 0 2 2 2 1 S1 domain KH_2 PF07650.17 AIM20041.1 - 0.0033 17.2 3.2 0.0047 16.7 0.2 2.5 2 0 0 2 2 2 1 KH domain DUF4172 PF13776.6 AIM20041.1 - 0.041 14.2 0.4 0.21 11.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4172) CsrA PF02599.16 AIM20041.1 - 0.041 13.8 0.4 3.1 7.8 0.0 2.7 2 0 0 2 2 2 0 Global regulator protein family SLS PF14611.6 AIM20041.1 - 0.096 12.5 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator TPR_2 PF07719.17 AIM20042.1 - 2.6e-14 52.1 9.7 5.7e-05 22.9 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 AIM20042.1 - 3.9e-14 51.8 7.6 1.2e-05 24.9 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 AIM20042.1 - 1.7e-12 47.3 10.2 8.7e-08 32.2 0.1 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 AIM20042.1 - 2.7e-09 37.4 3.3 2.8e-05 24.5 0.1 3.9 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 AIM20042.1 - 1e-08 34.7 3.7 0.0013 18.4 1.1 3.9 4 1 1 5 5 5 2 TPR repeat TPR_8 PF13181.6 AIM20042.1 - 2.9e-08 33.3 0.1 0.035 14.3 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 AIM20042.1 - 4.6e-08 33.6 11.6 0.00095 19.8 0.2 4.3 3 3 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 AIM20042.1 - 2.2e-07 31.1 6.6 0.0027 18.4 0.0 4.9 3 1 2 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 AIM20042.1 - 0.00048 20.3 2.2 1.5 9.4 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 AIM20042.1 - 0.0011 19.2 10.9 0.14 12.5 0.2 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TAtT PF16811.5 AIM20042.1 - 0.014 14.7 0.5 3 7.1 0.1 2.3 2 0 0 2 2 2 0 TRAP transporter T-component TPR_6 PF13174.6 AIM20042.1 - 0.016 15.8 14.8 7.1 7.5 0.4 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat RPN7 PF10602.9 AIM20042.1 - 0.039 13.7 0.8 0.28 10.9 0.1 2.4 2 1 0 2 2 2 0 26S proteasome subunit RPN7 TPR_7 PF13176.6 AIM20042.1 - 0.065 13.3 8.2 12 6.2 0.1 4.2 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 AIM20042.1 - 0.14 12.0 5.5 3.7 7.5 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat DEAD PF00270.29 AIM20043.1 - 3.7e-52 176.6 0.0 1.5e-51 174.6 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AIM20043.1 - 1.3e-30 106.0 0.0 1.2e-28 99.6 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DbpA PF03880.15 AIM20043.1 - 3.3e-20 71.9 0.0 7.2e-20 70.8 0.0 1.6 1 0 0 1 1 1 1 DbpA RNA binding domain DEADboxA PF12343.8 AIM20043.1 - 1.4e-12 48.0 33.4 1.4e-12 48.0 33.4 2.8 2 0 0 2 2 2 1 Cold shock protein DEAD box A ResIII PF04851.15 AIM20043.1 - 6.9e-05 22.9 0.0 0.00013 22.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 AIM20043.1 - 0.0054 16.1 0.0 0.0054 16.1 0.0 1.8 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit AAA_30 PF13604.6 AIM20043.1 - 0.013 15.3 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 AIM20043.1 - 0.073 13.4 0.1 0.14 12.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AIM20043.1 - 0.58 10.4 2.0 2.9 8.2 0.1 2.9 3 1 0 3 3 3 0 AAA domain Sulf_transp PF04143.14 AIM20044.1 - 1.5e-49 169.2 28.3 5.9e-25 88.5 6.6 2.3 2 0 0 2 2 2 2 Sulphur transport DUF4073 PF13285.6 AIM20044.1 - 0.0042 16.7 0.1 0.0062 16.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4073) TusA PF01206.17 AIM20045.1 - 2.6e-20 72.0 0.0 2.9e-20 71.8 0.0 1.0 1 0 0 1 1 1 1 Sulfurtransferase TusA DUF2249 PF10006.9 AIM20045.1 - 0.027 14.3 0.0 0.065 13.1 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2249) Bac_luciferase PF00296.20 AIM20046.1 - 4.1e-34 118.4 0.8 1e-32 113.8 0.8 2.0 1 1 0 1 1 1 1 Luciferase-like monooxygenase HlyD_D23 PF16576.5 AIM20047.1 - 1.2e-16 60.5 3.7 2.1e-14 53.3 3.7 2.5 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AIM20047.1 - 2.8e-11 44.1 0.2 7.8e-09 36.2 0.0 2.4 2 0 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AIM20047.1 - 4.9e-11 42.3 0.8 4.9e-11 42.3 0.8 5.0 6 0 0 6 6 6 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AIM20047.1 - 9.8e-08 31.7 0.6 0.028 14.3 0.0 3.4 4 0 0 4 4 4 2 Biotin-requiring enzyme PTS_EIIA_1 PF00358.20 AIM20047.1 - 0.014 15.2 0.1 0.24 11.2 0.0 2.5 3 0 0 3 3 3 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 HlyD_2 PF12700.7 AIM20047.1 - 0.036 12.8 0.4 3.7 6.2 0.0 2.8 2 1 0 2 2 2 0 HlyD family secretion protein DUF4407 PF14362.6 AIM20047.1 - 3.6 6.9 17.8 1.9 7.8 4.5 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) ABC2_membrane_3 PF12698.7 AIM20048.1 - 6.6e-23 81.4 17.1 9.3e-23 80.9 17.1 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 AIM20048.1 - 2.2e-08 33.8 21.5 8.1e-07 28.7 20.0 2.6 2 1 0 2 2 2 2 ABC-2 type transporter ABC2_membrane_2 PF12679.7 AIM20048.1 - 1.3 8.3 21.3 12 5.1 0.0 2.5 2 1 0 2 2 2 0 ABC-2 family transporter protein ABC2_membrane_3 PF12698.7 AIM20049.1 - 1.9e-30 106.2 16.8 3.4e-30 105.3 16.8 1.3 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 AIM20049.1 - 4.8e-15 55.5 14.6 4.8e-15 55.5 14.6 2.4 3 0 0 3 3 3 1 ABC-2 type transporter Esterase PF00756.20 AIM20050.1 - 2.1e-15 57.0 0.0 2.5e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 AIM20050.1 - 3.2e-06 26.6 0.0 4.2e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 AIM20050.1 - 0.011 15.2 0.1 0.028 13.9 0.1 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family CM_2 PF01817.21 AIM20051.1 - 5.3e-09 36.3 0.2 9e-08 32.4 0.0 2.4 2 1 0 2 2 2 1 Chorismate mutase type II Peptidase_U32 PF01136.19 AIM20052.1 - 4.5e-13 48.9 0.0 6.3e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family U32 Peptidase_U32 PF01136.19 AIM20053.1 - 5.1e-66 222.2 0.0 6.7e-66 221.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family U32 AP_endonuc_2 PF01261.24 AIM20053.1 - 0.017 14.6 0.2 0.03 13.7 0.2 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel SCP2 PF02036.17 AIM20054.1 - 1.7e-18 67.0 0.4 2.4e-18 66.5 0.4 1.2 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 AIM20054.1 - 1.8e-06 28.2 0.1 2.4e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal MDMPI_C PF07398.11 AIM20054.1 - 0.01 16.7 0.0 0.015 16.1 0.0 1.3 1 0 0 1 1 1 0 MDMPI C-terminal domain Acetyltransf_7 PF13508.7 AIM20055.1 - 2.8e-07 30.9 0.0 4.1e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AIM20055.1 - 6.2e-07 29.7 0.0 8.2e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 AIM20055.1 - 6.4e-06 26.3 0.0 8.7e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AIM20055.1 - 0.0026 17.8 0.0 0.0046 17.0 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.7 AIM20055.1 - 0.0059 16.5 0.0 0.0092 15.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GIY-YIG PF01541.24 AIM20056.1 - 7.9e-10 38.9 0.0 9.8e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 GIY-YIG catalytic domain AA_permease_2 PF13520.6 AIM20057.1 - 5.3e-46 157.3 54.3 6.3e-46 157.1 54.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 AIM20057.1 - 1.9e-17 63.0 45.2 2.7e-17 62.5 45.2 1.2 1 0 0 1 1 1 1 Amino acid permease OKR_DC_1 PF01276.20 AIM20058.1 - 1.4e-198 659.8 0.0 1.7e-198 659.5 0.0 1.1 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain OKR_DC_1_C PF03711.15 AIM20058.1 - 1.6e-49 167.6 0.3 8.5e-49 165.2 0.1 2.1 2 0 0 2 2 2 1 Orn/Lys/Arg decarboxylase, C-terminal domain OKR_DC_1_N PF03709.15 AIM20058.1 - 3e-22 79.0 0.0 5.6e-22 78.1 0.0 1.5 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, N-terminal domain Beta_elim_lyase PF01212.21 AIM20058.1 - 0.0011 18.3 0.0 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase DUF2618 PF10940.8 AIM20059.1 - 2.7e-11 43.1 8.8 2.8e-11 43.0 8.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2618) Putative_PNPOx PF01243.20 AIM20060.1 - 0.079 13.2 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase NAD_binding_10 PF13460.6 AIM20061.1 - 2.7e-09 37.2 0.0 3.5e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 AIM20061.1 - 2.1e-06 28.1 0.0 4.8e-05 23.8 0.0 2.1 1 1 1 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain HIM1 PF08732.10 AIM20061.1 - 2e-05 24.1 0.0 2.9e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 HIM1 NAD_binding_4 PF07993.12 AIM20061.1 - 0.00038 19.7 0.0 0.18 10.9 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 AIM20061.1 - 0.0019 17.4 0.0 0.6 9.2 0.0 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain PALP PF00291.25 AIM20061.1 - 0.027 13.9 0.0 0.064 12.7 0.0 1.6 1 1 1 2 2 2 0 Pyridoxal-phosphate dependent enzyme Epimerase PF01370.21 AIM20061.1 - 0.063 12.7 0.0 0.1 12.0 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Lactamase_B_2 PF12706.7 AIM20062.1 - 5.3e-19 68.5 0.0 7.2e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 AIM20062.1 - 0.0012 18.9 0.1 0.0021 18.1 0.1 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily PDEase_II PF02112.15 AIM20062.1 - 0.013 14.6 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II Hexapep PF00132.24 AIM20063.1 - 1.4e-12 46.8 5.6 4.2e-08 32.6 4.0 3.8 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AIM20063.1 - 3.8e-06 26.5 2.6 2e-05 24.3 0.7 2.5 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase RtcB PF01139.17 AIM20063.1 - 0.13 11.4 0.6 0.18 11.0 0.6 1.2 1 0 0 1 1 1 0 tRNA-splicing ligase RtcB AAA_18 PF13238.6 AIM20064.1 - 6.4e-06 26.8 0.0 6.5e-05 23.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain Guanylate_kin PF00625.21 AIM20064.1 - 0.00026 20.7 0.0 0.0024 17.6 0.0 2.0 1 1 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.6 AIM20064.1 - 0.00046 20.4 0.1 0.5 10.5 0.3 2.2 2 0 0 2 2 2 2 AAA domain Ploopntkinase3 PF18751.1 AIM20064.1 - 0.0017 18.3 0.0 0.0034 17.3 0.0 1.5 1 1 0 1 1 1 1 P-loop Nucleotide Kinase3 AAA_16 PF13191.6 AIM20064.1 - 0.021 15.2 1.3 0.18 12.1 1.3 2.0 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 AIM20064.1 - 0.024 14.6 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_28 PF13521.6 AIM20064.1 - 0.045 14.0 0.0 0.16 12.2 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_PrkA PF08298.11 AIM20064.1 - 0.081 11.8 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 PrkA AAA domain ABC_tran PF00005.27 AIM20064.1 - 0.082 13.4 0.0 0.19 12.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 AIM20064.1 - 0.14 12.4 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Amidohydro_3 PF07969.11 AIM20065.1 - 1.1e-11 44.9 9.1 2.7e-10 40.3 4.5 2.4 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 AIM20065.1 - 1.2e-08 34.7 0.6 1.5e-07 31.1 0.6 2.4 1 1 0 1 1 1 1 Amidohydrolase family ABC_tran PF00005.27 AIM20066.1 - 7.2e-28 97.8 0.0 9.2e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 AIM20066.1 - 2.5e-08 34.5 0.0 4.5e-08 33.7 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 AIM20066.1 - 8.6e-06 25.3 0.0 0.0016 17.9 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 AIM20066.1 - 6.7e-05 23.1 0.2 0.00055 20.1 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 AIM20066.1 - 9.5e-05 22.3 0.0 0.062 13.1 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 AIM20066.1 - 0.00023 21.4 0.0 0.00039 20.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AIM20066.1 - 0.00037 20.2 0.0 0.00071 19.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 AIM20066.1 - 0.0013 18.4 0.2 0.02 14.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 AIM20066.1 - 0.0017 18.3 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase NACHT PF05729.12 AIM20066.1 - 0.007 16.3 0.0 0.019 14.9 0.0 1.7 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 AIM20066.1 - 0.016 14.9 0.0 0.075 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 AIM20066.1 - 0.018 14.4 0.0 0.036 13.4 0.0 1.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family TsaE PF02367.17 AIM20066.1 - 0.038 14.0 0.3 0.44 10.6 0.1 2.1 1 1 1 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 AIM20066.1 - 0.062 13.3 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 AIM20066.1 - 0.064 13.6 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Viral_helicase1 PF01443.18 AIM20066.1 - 0.069 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.6 AIM20066.1 - 0.074 13.5 0.0 0.11 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 AIM20066.1 - 0.078 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.6 AIM20066.1 - 0.085 13.1 0.2 0.81 10.0 0.0 2.2 1 1 1 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 AIM20066.1 - 0.1 12.8 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 AIM20066.1 - 0.12 11.5 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain MMR_HSR1 PF01926.23 AIM20066.1 - 0.13 12.4 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase IstB_IS21 PF01695.17 AIM20066.1 - 0.14 11.9 0.0 0.95 9.2 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF815 PF05673.13 AIM20066.1 - 0.14 11.3 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 AIM20066.1 - 0.18 11.3 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 AIM20067.1 - 6.3e-30 104.5 0.0 8.2e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIM20067.1 - 3.7e-06 27.0 0.0 0.056 13.2 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system oligo_HPY PF08352.12 AIM20067.1 - 8e-06 26.3 0.0 1.5e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_29 PF13555.6 AIM20067.1 - 2.3e-05 24.1 0.0 6.9e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AIM20067.1 - 0.00015 22.2 0.2 0.00036 21.0 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AIM20067.1 - 0.00092 19.5 0.0 0.0063 16.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 AIM20067.1 - 0.00096 18.8 0.1 0.0031 17.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 AIM20067.1 - 0.001 19.0 0.1 0.0023 17.9 0.0 1.6 2 0 0 2 2 2 1 NACHT domain AAA_23 PF13476.6 AIM20067.1 - 0.0036 17.8 0.0 0.0051 17.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain MobB PF03205.14 AIM20067.1 - 0.0056 16.6 0.0 0.0091 15.9 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B SMC_N PF02463.19 AIM20067.1 - 0.0075 15.7 0.2 0.085 12.3 0.2 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain cobW PF02492.19 AIM20067.1 - 0.012 15.2 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 AIM20067.1 - 0.013 15.4 0.0 0.069 13.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 AIM20067.1 - 0.02 14.1 0.0 0.033 13.4 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 AIM20067.1 - 0.02 14.6 0.0 0.058 13.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 AIM20067.1 - 0.022 14.9 0.0 0.05 13.7 0.0 1.5 2 0 0 2 2 1 0 Helicase HerA, central domain RNA_helicase PF00910.22 AIM20067.1 - 0.025 15.0 0.0 0.042 14.2 0.0 1.3 1 0 0 1 1 1 0 RNA helicase SbcCD_C PF13558.6 AIM20067.1 - 0.027 14.7 0.0 0.051 13.8 0.0 1.5 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 AIM20067.1 - 0.041 14.1 0.0 0.065 13.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 AIM20067.1 - 0.042 13.7 0.0 0.075 12.9 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Pox_A32 PF04665.12 AIM20067.1 - 0.059 12.8 0.0 0.091 12.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein PRK PF00485.18 AIM20067.1 - 0.062 13.0 0.0 0.096 12.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_14 PF13173.6 AIM20067.1 - 0.089 12.8 0.0 0.22 11.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 AIM20067.1 - 0.1 12.3 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 AIM20067.1 - 0.12 12.3 0.0 0.81 9.6 0.0 2.0 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_19 PF13245.6 AIM20067.1 - 0.13 12.6 0.0 0.59 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 AIM20067.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 AIM20067.1 - 0.15 12.1 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.6 AIM20067.1 - 0.18 12.4 0.0 0.35 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 AIM20067.1 - 0.18 11.5 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Septin PF00735.18 AIM20067.1 - 0.18 11.0 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Septin NTPase_1 PF03266.15 AIM20067.1 - 0.19 11.6 0.1 0.47 10.3 0.1 1.6 2 0 0 2 2 2 0 NTPase AAA_15 PF13175.6 AIM20067.1 - 0.21 11.3 0.0 1.1 8.8 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain PhnJ PF06007.11 AIM20068.1 - 7.6e-148 490.9 0.0 8.8e-148 490.7 0.0 1.0 1 0 0 1 1 1 1 Phosphonate metabolism protein PhnJ PhnA_Zn_Ribbon PF08274.12 AIM20068.1 - 0.054 13.5 1.1 0.11 12.5 1.1 1.4 1 0 0 1 1 1 0 PhnA Zinc-Ribbon PhnI PF05861.12 AIM20069.1 - 2.9e-155 516.5 0.0 3.3e-155 516.3 0.0 1.0 1 0 0 1 1 1 1 Bacterial phosphonate metabolism protein (PhnI) PhnG PF06754.12 AIM20069.1 - 7.2e-05 22.8 0.2 0.00015 21.7 0.0 1.8 2 0 0 2 2 2 1 Phosphonate metabolism protein PhnG PhnH PF05845.12 AIM20070.1 - 9.1e-59 198.4 0.5 1e-58 198.2 0.5 1.0 1 0 0 1 1 1 1 Bacterial phosphonate metabolism protein (PhnH) MASE1 PF05231.14 AIM20070.1 - 0.07 12.3 0.2 0.1 11.8 0.2 1.2 1 0 0 1 1 1 0 MASE1 PhnG PF06754.12 AIM20071.1 - 1.6e-57 193.4 0.5 1.8e-57 193.3 0.5 1.0 1 0 0 1 1 1 1 Phosphonate metabolism protein PhnG UTRA PF07702.13 AIM20072.1 - 1.5e-28 99.4 0.3 2.3e-28 98.8 0.3 1.3 1 0 0 1 1 1 1 UTRA domain GntR PF00392.21 AIM20072.1 - 2.6e-20 71.8 0.4 5.5e-20 70.8 0.4 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family MarR PF01047.22 AIM20072.1 - 1.2e-05 25.1 0.0 3e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.20 AIM20072.1 - 0.00012 22.3 0.0 0.0016 18.7 0.0 2.6 2 1 1 3 3 3 1 Transcriptional regulator MarR_2 PF12802.7 AIM20072.1 - 0.00023 21.0 0.0 0.0009 19.1 0.0 2.0 1 0 0 1 1 1 1 MarR family HTH_Crp_2 PF13545.6 AIM20072.1 - 0.00045 20.1 0.1 0.0013 18.6 0.1 1.9 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_36 PF13730.6 AIM20072.1 - 0.0011 18.9 0.0 0.0025 17.7 0.0 1.6 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_DeoR PF08220.12 AIM20072.1 - 0.0014 18.3 0.1 0.0041 16.8 0.1 1.7 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain RP-C PF03428.13 AIM20072.1 - 0.0066 16.1 0.4 0.017 14.7 0.0 1.8 2 0 0 2 2 2 1 Replication protein C N-terminal domain TrmB PF01978.19 AIM20072.1 - 0.16 11.9 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB ArsP_1 PF03773.13 AIM20073.1 - 2.8e-31 108.8 29.7 1.6e-26 93.1 24.5 2.3 1 1 1 2 2 2 2 Predicted permease VEK-30 PF12107.8 AIM20074.1 - 0.043 13.7 0.7 0.1 12.5 0.7 1.6 1 0 0 1 1 1 0 Plasminogen (Pg) ligand in fibrinolytic pathway DUF4238 PF14022.6 AIM20075.1 - 1.6e-13 50.8 0.7 1e-11 44.9 0.7 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF4238) Fer4_12 PF13353.6 AIM20076.1 - 8e-51 172.0 0.0 9e-51 171.8 0.0 1.0 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AIM20076.1 - 3.3e-34 117.5 0.0 4.1e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 4Fe-4S single cluster domain Radical_SAM PF04055.21 AIM20076.1 - 0.002 18.6 0.0 0.0024 18.3 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily NRDD PF13597.6 AIM20077.1 - 1.5e-179 598.4 0.0 1.9e-179 598.1 0.0 1.1 1 0 0 1 1 1 1 Anaerobic ribonucleoside-triphosphate reductase Gly_radical PF01228.21 AIM20077.1 - 1.7e-28 99.3 0.0 2.6e-27 95.4 0.0 2.4 2 0 0 2 2 2 1 Glycine radical ATP-cone PF03477.16 AIM20077.1 - 1.6e-21 76.7 1.4 3.4e-20 72.4 1.1 2.4 2 0 0 2 2 2 1 ATP cone domain Zn_Tnp_IS91 PF14319.6 AIM20077.1 - 0.093 12.8 0.4 0.2 11.7 0.4 1.5 1 0 0 1 1 1 0 Transposase zinc-binding domain OrfB_Zn_ribbon PF07282.11 AIM20077.1 - 0.12 12.3 1.3 0.36 10.8 1.3 1.8 1 0 0 1 1 1 0 Putative transposase DNA-binding domain NOB1_Zn_bind PF08772.11 AIM20077.1 - 0.19 11.9 3.8 0.45 10.7 3.8 1.6 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like Anti-TRAP PF15777.5 AIM20077.1 - 0.35 10.9 1.8 0.88 9.6 1.8 1.6 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein LysR_substrate PF03466.20 AIM20078.1 - 1.6e-48 164.9 7.2 1.9e-48 164.6 7.2 1.1 1 0 0 1 1 1 1 LysR substrate binding domain TUG-UBL1 PF11470.8 AIM20078.1 - 0.062 13.5 0.4 1.1 9.5 0.1 2.2 2 0 0 2 2 2 0 TUG ubiquitin-like domain Flavodoxin_2 PF02525.17 AIM20079.1 - 3.3e-42 144.4 0.0 3.8e-42 144.2 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 AIM20079.1 - 1.1e-05 25.3 0.0 1.5e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase DUF1400 PF07176.11 AIM20079.1 - 0.067 13.5 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1400) Sirohm_synth_M PF14824.6 AIM20079.1 - 0.12 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Sirohaem biosynthesis protein central PP_kinase_C_1 PF17941.1 AIM20079.1 - 0.21 11.1 0.0 1.4 8.4 0.0 1.9 2 0 0 2 2 2 0 Polyphosphate kinase C-terminal domain 1 Alpha-amylase PF00128.24 AIM20080.1 - 1.7e-126 422.4 0.1 2.2e-126 422.0 0.1 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF3459 PF11941.8 AIM20080.1 - 2.1e-13 50.4 3.1 2e-12 47.2 2.3 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3459) Malt_amylase_C PF16657.5 AIM20080.1 - 1.2e-06 28.6 0.0 2.3e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 AIM20080.1 - 0.00017 20.8 0.0 0.00025 20.2 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Aminotran_5 PF00266.19 AIM20080.1 - 0.094 11.7 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V PTS_EIIC PF02378.18 AIM20081.1 - 4e-33 114.8 26.6 4e-33 114.8 26.6 1.4 2 0 0 2 2 2 1 Phosphotransferase system, EIIC PTS_EIIB PF00367.20 AIM20081.1 - 3.1e-13 48.9 0.1 5.7e-13 48.1 0.1 1.4 1 0 0 1 1 1 1 phosphotransferase system, EIIB LacI PF00356.21 AIM20082.1 - 5.7e-21 74.0 0.0 9.4e-21 73.3 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_3 PF13377.6 AIM20082.1 - 3.7e-17 63.2 0.1 7.1e-17 62.2 0.1 1.5 1 0 0 1 1 1 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 AIM20082.1 - 1.1e-12 48.0 0.0 1.5e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family HTH_3 PF01381.22 AIM20082.1 - 0.00011 22.2 0.0 0.0002 21.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 AIM20082.1 - 0.00068 19.9 0.1 0.0041 17.4 0.1 2.1 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_IclR PF09339.10 AIM20082.1 - 0.00081 19.1 0.0 0.0053 16.5 0.0 2.3 2 0 0 2 2 2 1 IclR helix-turn-helix domain Peripla_BP_4 PF13407.6 AIM20082.1 - 0.0011 18.6 0.0 0.002 17.8 0.0 1.5 1 1 0 1 1 1 1 Periplasmic binding protein domain HTH_23 PF13384.6 AIM20082.1 - 0.005 16.6 0.0 0.016 15.0 0.0 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.15 AIM20082.1 - 0.0058 16.7 0.1 0.018 15.1 0.0 1.9 2 0 0 2 2 1 1 Helix-turn-helix domain of resolvase MarR_2 PF12802.7 AIM20082.1 - 0.0096 15.8 0.0 0.032 14.1 0.0 1.9 1 0 0 1 1 1 1 MarR family HTH_Tnp_ISL3 PF13542.6 AIM20082.1 - 0.012 15.0 0.0 0.026 13.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_38 PF13936.6 AIM20082.1 - 0.023 14.4 0.1 0.19 11.5 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain CENP-B_N PF04218.13 AIM20082.1 - 0.026 14.1 0.0 0.065 12.9 0.0 1.6 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain MarR PF01047.22 AIM20082.1 - 0.076 13.0 0.0 0.25 11.3 0.0 1.9 2 0 0 2 2 2 0 MarR family HTH_Crp_2 PF13545.6 AIM20082.1 - 0.077 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_AraC PF00165.23 AIM20082.1 - 0.1 12.7 0.0 0.51 10.5 0.0 2.2 3 0 0 3 3 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family SpoIIID PF12116.8 AIM20082.1 - 0.1 12.7 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Stage III sporulation protein D HHH PF00633.23 AIM20082.1 - 0.14 12.1 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif TrmB PF01978.19 AIM20082.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 AIM20082.1 - 0.15 11.7 0.1 0.4 10.3 0.1 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_17 PF12728.7 AIM20082.1 - 0.16 12.1 0.0 0.37 11.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_36 PF13730.6 AIM20082.1 - 0.18 11.8 0.0 0.38 10.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain E1-E2_ATPase PF00122.20 AIM20083.1 - 1.1e-43 148.9 0.5 1.1e-43 148.9 0.5 2.3 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 AIM20083.1 - 8.4e-21 75.2 0.4 1.9e-20 74.1 0.4 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 AIM20083.1 - 1.7e-13 50.7 10.8 1.7e-13 50.7 10.8 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 AIM20083.1 - 3.3e-13 49.1 0.0 8e-13 47.9 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 AIM20083.1 - 3.5e-10 39.8 0.0 8.4e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 AIM20083.1 - 6.5e-06 26.1 0.4 0.0013 18.5 0.2 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 AIM20083.1 - 0.00035 21.0 0.6 0.0014 19.0 0.0 2.2 2 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase Glyco_hydro_20 PF00728.22 AIM20084.1 - 3.4e-104 349.0 0.1 6.7e-102 341.5 0.1 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 AIM20084.1 - 1.4e-15 58.2 0.5 5.3e-14 53.1 0.0 2.9 3 0 0 3 3 3 1 Glycosyl hydrolase family 20, domain 2 Glycohydro_20b2 PF14845.6 AIM20084.1 - 6.6e-10 39.8 0.0 2.9e-09 37.7 0.0 2.1 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Proteasome PF00227.26 AIM20085.1 - 1.6e-08 34.2 0.0 9.3e-08 31.8 0.0 1.9 1 1 0 1 1 1 1 Proteasome subunit Bact_transglu_N PF08379.10 AIM20086.1 - 5.1e-23 81.8 1.2 5.1e-23 81.8 1.2 1.9 3 0 0 3 3 3 1 Bacterial transglutaminase-like N-terminal region Transglut_core PF01841.19 AIM20086.1 - 4.2e-22 78.7 0.2 7.4e-22 77.9 0.2 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily Transglut_core3 PF13471.6 AIM20086.1 - 0.0084 16.0 0.3 0.016 15.1 0.3 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.12 AIM20086.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Transglutaminase-like domain Alpha-E PF04168.12 AIM20087.1 - 4e-86 289.4 0.9 4.5e-86 289.3 0.9 1.0 1 0 0 1 1 1 1 A predicted alpha-helical domain with a conserved ER motif. CP_ATPgrasp_2 PF14403.6 AIM20088.1 - 5e-163 542.4 0.1 5.9e-163 542.2 0.1 1.0 1 0 0 1 1 1 1 Circularly permuted ATP-grasp type 2 CP_ATPgrasp_1 PF04174.13 AIM20088.1 - 9.7e-156 517.9 0.3 1.2e-155 517.6 0.3 1.1 1 0 0 1 1 1 1 A circularly permuted ATPgrasp ATP-grasp_3 PF02655.14 AIM20088.1 - 0.1 12.6 0.0 12 6.0 0.0 2.3 2 0 0 2 2 2 0 ATP-grasp domain Ribonuc_L-PSP PF01042.21 AIM20089.1 - 2.5e-43 146.9 1.0 2.8e-43 146.8 1.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DHquinase_I PF01487.15 AIM20089.1 - 0.012 15.9 0.1 0.015 15.6 0.1 1.1 1 0 0 1 1 1 0 Type I 3-dehydroquinase YjgF_endoribonc PF14588.6 AIM20089.1 - 0.081 13.1 0.1 0.22 11.7 0.1 1.8 1 1 0 1 1 1 0 YjgF/chorismate_mutase-like, putative endoribonuclease PyrI PF01948.18 AIM20090.1 - 8.4e-30 102.9 0.0 1.2e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 Aspartate carbamoyltransferase regulatory chain, allosteric domain PyrI_C PF02748.15 AIM20090.1 - 3.6e-18 65.2 0.7 7.3e-18 64.2 0.7 1.5 1 0 0 1 1 1 1 Aspartate carbamoyltransferase regulatory chain, metal binding domain OTCace_N PF02729.21 AIM20091.1 - 4.8e-47 159.7 0.0 1.1e-46 158.6 0.0 1.6 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 AIM20091.1 - 3.6e-27 95.4 0.0 5.3e-27 94.8 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain SBP_bac_5 PF00496.22 AIM20092.1 - 2.4e-71 240.7 6.4 3.6e-71 240.1 6.4 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle OTCace PF00185.24 AIM20093.1 - 6.8e-58 195.2 0.1 2e-57 193.7 0.1 1.7 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 AIM20093.1 - 7.3e-47 159.1 0.0 1.2e-46 158.4 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain DUF1820 PF08850.11 AIM20093.1 - 0.16 12.5 0.0 0.28 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1820) RraB PF06877.11 AIM20094.1 - 2.4e-34 118.1 0.5 3.6e-34 117.6 0.5 1.3 1 0 0 1 1 1 1 Regulator of ribonuclease activity B MiaE PF06175.11 AIM20095.1 - 1.7e-107 358.5 0.1 2e-107 358.3 0.1 1.0 1 0 0 1 1 1 1 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) Rubrerythrin PF02915.17 AIM20095.1 - 0.04 14.3 0.0 0.057 13.8 0.0 1.2 1 0 0 1 1 1 0 Rubrerythrin GMC_oxred_N PF00732.19 AIM20096.1 - 1.5e-86 290.5 0.0 1.9e-86 290.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 AIM20096.1 - 5.6e-37 127.5 0.0 9.1e-37 126.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 AIM20096.1 - 2.1e-06 27.1 1.3 0.032 13.3 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 AIM20096.1 - 0.00025 20.2 0.8 0.00064 18.9 0.1 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 AIM20096.1 - 0.00058 19.5 4.4 0.0021 17.7 4.4 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AIM20096.1 - 0.0006 20.0 1.2 0.0019 18.4 0.9 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AIM20096.1 - 0.00067 19.0 0.3 0.0025 17.1 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AIM20096.1 - 0.011 15.0 0.2 3 7.0 0.4 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AIM20096.1 - 0.026 13.2 0.1 0.04 12.6 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 AIM20096.1 - 0.16 11.1 0.2 0.25 10.4 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Acetyltransf_1 PF00583.25 AIM20097.1 - 6.7e-14 52.1 0.0 8.2e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AIM20097.1 - 2.3e-10 40.7 0.1 3.4e-10 40.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AIM20097.1 - 4.7e-10 39.5 0.0 5.7e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AIM20097.1 - 1e-06 29.4 0.0 1.3e-06 29.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AIM20097.1 - 1.2e-05 25.4 0.0 2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 AIM20097.1 - 4.3e-05 23.4 0.0 9.2e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 AIM20097.1 - 0.0037 17.4 0.0 0.0042 17.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AIM20097.1 - 0.06 13.4 0.0 0.33 11.0 0.0 1.9 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain tRNA-synt_1 PF00133.22 AIM20098.1 - 1.2e-231 770.2 0.1 1.5e-230 766.6 0.1 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 AIM20098.1 - 3.2e-45 153.8 0.2 5.6e-45 153.0 0.2 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Val_tRNA-synt_C PF10458.9 AIM20098.1 - 3.6e-19 68.8 3.1 8.7e-19 67.6 3.1 1.7 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1g PF09334.11 AIM20098.1 - 3.4e-18 65.6 0.8 1.3e-07 30.8 0.1 4.9 4 2 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 AIM20098.1 - 5e-07 29.4 0.0 7.3e-05 22.4 0.0 2.4 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 ABC_tran_CTD PF16326.5 AIM20098.1 - 0.011 15.9 1.2 0.039 14.2 1.2 2.0 1 0 0 1 1 1 0 ABC transporter C-terminal domain tRNA-synt_1f PF01921.18 AIM20098.1 - 0.045 12.7 0.0 0.081 11.8 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) tRNA-synt_1b PF00579.25 AIM20098.1 - 1 8.6 3.9 0.33 10.2 0.0 2.0 3 0 0 3 3 3 0 tRNA synthetases class I (W and Y) DNA_pol3_chi PF04364.13 AIM20099.1 - 3.1e-40 137.5 0.0 3.5e-40 137.3 0.0 1.0 1 0 0 1 1 1 1 DNA polymerase III chi subunit, HolC GARS_A PF01071.19 AIM20099.1 - 0.2 11.4 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Peptidase_M17 PF00883.21 AIM20100.1 - 4.6e-123 410.5 0.1 7.6e-123 409.7 0.1 1.4 2 0 0 2 2 2 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 AIM20100.1 - 4.1e-34 117.2 0.1 2.2e-33 114.8 0.0 2.2 2 1 0 2 2 2 1 Cytosol aminopeptidase family, N-terminal domain LptF_LptG PF03739.14 AIM20101.1 - 6.3e-75 252.2 5.3 7.3e-75 252.0 5.3 1.0 1 0 0 1 1 1 1 Lipopolysaccharide export system permease LptF/LptG Claudin_2 PF13903.6 AIM20101.1 - 0.28 10.9 3.6 1.1 9.0 0.8 2.4 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction LptF_LptG PF03739.14 AIM20102.1 - 1.3e-72 244.6 8.1 1.5e-72 244.4 8.1 1.0 1 0 0 1 1 1 1 Lipopolysaccharide export system permease LptF/LptG Autoind_bind PF03472.15 AIM20103.1 - 3.1e-25 88.4 0.0 4.4e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 Autoinducer binding domain GerE PF00196.19 AIM20103.1 - 5.9e-15 54.6 0.1 1.1e-14 53.7 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AIM20103.1 - 9.1e-05 22.1 0.0 0.00046 19.8 0.0 2.1 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AIM20103.1 - 0.00042 19.8 0.0 0.00087 18.8 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_10 PF04967.12 AIM20103.1 - 0.03 14.1 0.0 0.27 11.1 0.0 2.3 2 0 0 2 2 2 0 HTH DNA binding domain HTH_38 PF13936.6 AIM20103.1 - 0.13 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain YukC PF10140.9 AIM20103.1 - 0.17 10.7 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC rve_3 PF13683.6 AIM20104.1 - 6.2e-28 96.4 0.3 9.7e-28 95.7 0.3 1.3 1 0 0 1 1 1 1 Integrase core domain rve PF00665.26 AIM20104.1 - 1.5e-22 80.0 0.0 2.1e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_2 PF13333.6 AIM20104.1 - 9.1e-05 22.6 1.3 0.00019 21.5 1.3 1.6 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 AIM20104.1 - 0.047 13.9 0.0 0.054 13.7 0.0 1.2 1 0 0 1 1 1 0 DDE domain HTH_21 PF13276.6 AIM20105.1 - 4e-09 36.5 1.2 6.2e-09 35.9 1.2 1.2 1 0 0 1 1 1 1 HTH-like domain HTH_Tnp_1 PF01527.20 AIM20106.1 - 4.8e-23 81.3 0.1 6.3e-23 80.9 0.1 1.2 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 AIM20106.1 - 1.2e-05 24.9 0.0 1.9e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 AIM20106.1 - 0.00012 21.5 0.4 0.0043 16.4 0.1 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 LZ_Tnp_IS481 PF13011.6 AIM20106.1 - 0.00016 22.1 0.0 0.00017 22.0 0.0 1.2 1 0 0 1 1 1 1 leucine-zipper of insertion element IS481 HTH_28 PF13518.6 AIM20106.1 - 0.00026 21.0 0.0 0.00042 20.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_1_2 PF13022.6 AIM20106.1 - 0.00054 20.1 0.3 0.001 19.2 0.3 1.6 1 1 0 1 1 1 1 Helix-turn-helix of insertion element transposase HTH_29 PF13551.6 AIM20106.1 - 0.0091 16.0 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix Terminase_5 PF06056.12 AIM20106.1 - 0.026 14.4 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_7 PF02796.15 AIM20106.1 - 0.057 13.5 0.0 0.095 12.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase DUF1657 PF07870.11 AIM20106.1 - 0.08 12.8 0.5 3.5 7.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1657) DNA_methylase PF00145.17 AIM20107.1 - 1.3e-55 189.1 0.0 1.5e-55 188.9 0.0 1.0 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Methyltransf_15 PF09445.10 AIM20107.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase fn1 PF00039.18 AIM20107.1 - 0.18 12.0 0.7 0.38 11.0 0.7 1.6 1 0 0 1 1 1 0 Fibronectin type I domain N6_Mtase PF02384.16 AIM20108.1 - 2.1e-05 23.9 0.0 0.0072 15.6 0.0 2.8 2 1 0 2 2 2 2 N-6 DNA Methylase UPF0020 PF01170.18 AIM20108.1 - 0.12 12.0 0.0 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Helicase_C PF00271.31 AIM20109.1 - 3e-05 24.3 0.0 0.00013 22.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DnaA_N PF11638.8 AIM20109.1 - 0.051 13.3 0.0 0.19 11.5 0.0 1.9 2 0 0 2 2 2 0 DnaA N-terminal domain PLDc_2 PF13091.6 AIM20110.1 - 1.6e-17 63.7 0.1 2.2e-17 63.2 0.1 1.2 1 0 0 1 1 1 1 PLD-like domain PLDc PF00614.22 AIM20110.1 - 9.4e-06 25.6 0.0 3.7e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 Phospholipase D Active site motif Pyr_redox_dim PF02852.22 AIM20110.1 - 0.0079 16.4 0.3 0.27 11.5 0.0 2.8 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain HTH_Tnp_1 PF01527.20 AIM20111.1 - 4.8e-23 81.3 0.1 6.3e-23 80.9 0.1 1.2 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 AIM20111.1 - 1.2e-05 24.9 0.0 1.9e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 AIM20111.1 - 0.00012 21.5 0.4 0.0043 16.4 0.1 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 LZ_Tnp_IS481 PF13011.6 AIM20111.1 - 0.00016 22.1 0.0 0.00017 22.0 0.0 1.2 1 0 0 1 1 1 1 leucine-zipper of insertion element IS481 HTH_28 PF13518.6 AIM20111.1 - 0.00026 21.0 0.0 0.00042 20.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_1_2 PF13022.6 AIM20111.1 - 0.00054 20.1 0.3 0.001 19.2 0.3 1.6 1 1 0 1 1 1 1 Helix-turn-helix of insertion element transposase HTH_29 PF13551.6 AIM20111.1 - 0.0091 16.0 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix Terminase_5 PF06056.12 AIM20111.1 - 0.026 14.4 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_7 PF02796.15 AIM20111.1 - 0.057 13.5 0.0 0.095 12.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase DUF1657 PF07870.11 AIM20111.1 - 0.08 12.8 0.5 3.5 7.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1657) HTH_21 PF13276.6 AIM20112.1 - 4e-09 36.5 1.2 6.2e-09 35.9 1.2 1.2 1 0 0 1 1 1 1 HTH-like domain rve_3 PF13683.6 AIM20113.1 - 6e-28 96.4 0.3 9.7e-28 95.7 0.3 1.3 1 0 0 1 1 1 1 Integrase core domain rve PF00665.26 AIM20113.1 - 2.1e-22 79.5 0.0 2.8e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_2 PF13333.6 AIM20113.1 - 9.2e-05 22.5 1.3 0.00019 21.5 1.3 1.5 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 AIM20113.1 - 0.053 13.7 0.0 0.06 13.6 0.0 1.2 1 0 0 1 1 1 0 DDE domain DUF1524 PF07510.11 AIM20114.1 - 8.6e-34 116.4 0.0 1.6e-33 115.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) DUF262 PF03235.14 AIM20114.1 - 2.4e-10 41.0 0.5 2e-09 38.0 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function DUF262 HNH_2 PF13391.6 AIM20115.1 - 1.7e-12 47.2 0.1 6.4e-12 45.4 0.1 2.0 1 1 0 1 1 1 1 HNH endonuclease RNAse_A_bac PF18431.1 AIM20118.1 - 1.2e-28 100.4 0.0 1.8e-28 99.8 0.0 1.3 1 0 0 1 1 1 1 Bacterial CdiA-CT RNAse A domain CdiI_2 PF18593.1 AIM20119.1 - 1.6e-18 67.1 0.3 1.9e-18 66.9 0.3 1.0 1 0 0 1 1 1 1 CdiI immunity protein CdiI_2 PF18593.1 AIM20120.1 - 4.1e-23 81.8 0.2 4.6e-23 81.7 0.2 1.0 1 0 0 1 1 1 1 CdiI immunity protein Glyco_hydro_1 PF00232.18 AIM20122.1 - 2.6e-134 448.1 0.0 3.6e-134 447.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Cellulase PF00150.18 AIM20122.1 - 0.095 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) PTS_EIIC PF02378.18 AIM20123.1 - 5e-40 137.5 32.1 8.7e-40 136.7 32.1 1.4 1 0 0 1 1 1 1 Phosphotransferase system, EIIC PTS_EIIB PF00367.20 AIM20123.1 - 1.8e-15 56.2 0.1 3.3e-15 55.3 0.1 1.5 1 0 0 1 1 1 1 phosphotransferase system, EIIB Peripla_BP_3 PF13377.6 AIM20124.1 - 4.2e-37 128.0 0.0 8.2e-37 127.1 0.0 1.5 1 0 0 1 1 1 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 AIM20124.1 - 2.3e-23 83.0 0.1 2.8e-23 82.7 0.1 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 AIM20124.1 - 2.3e-18 65.7 0.4 4.3e-18 64.8 0.4 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 AIM20124.1 - 3.9e-17 62.7 0.1 1e-16 61.3 0.0 1.6 2 0 0 2 2 2 1 Periplasmic binding protein domain HTH_3 PF01381.22 AIM20124.1 - 0.004 17.2 0.1 0.0084 16.1 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 AIM20124.1 - 0.0061 16.9 0.1 0.015 15.6 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_7 PF02796.15 AIM20124.1 - 0.043 13.9 0.4 1.6 8.9 0.0 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase TetR_N PF00440.23 AIM20124.1 - 0.078 12.8 0.2 0.28 11.0 0.2 1.9 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family HTH_38 PF13936.6 AIM20124.1 - 0.14 11.9 0.3 1.8 8.4 0.1 2.9 2 0 0 2 2 2 0 Helix-turn-helix domain GDP_Man_Dehyd PF16363.5 AIM20125.1 - 6.4e-99 331.5 0.0 7.3e-99 331.3 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 AIM20125.1 - 1.2e-74 250.9 0.0 1.4e-74 250.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 AIM20125.1 - 3.9e-15 55.8 0.0 6e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 AIM20125.1 - 7.6e-14 51.5 0.0 1.2e-13 50.8 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 AIM20125.1 - 4.3e-13 48.9 0.0 7.3e-13 48.2 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 AIM20125.1 - 2.6e-12 46.5 0.0 1.4e-09 37.5 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein adh_short PF00106.25 AIM20125.1 - 2.5e-07 30.4 0.1 0.0016 17.9 0.0 2.6 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 AIM20125.1 - 5.7e-05 23.1 0.1 0.00015 21.7 0.0 1.7 2 0 0 2 2 2 1 KR domain Sacchrp_dh_NADP PF03435.18 AIM20125.1 - 0.016 15.5 0.0 0.029 14.6 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 AIM20125.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding NTP_transferase PF00483.23 AIM20126.1 - 8.9e-68 228.5 0.0 1e-67 228.3 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AIM20126.1 - 8.7e-09 35.9 0.0 1.1e-08 35.6 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 AIM20126.1 - 0.002 17.9 0.0 0.0043 16.8 0.0 1.5 2 0 0 2 2 2 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Glyco_transf_56 PF07429.11 AIM20127.1 - 3.1e-34 118.7 0.8 3.7e-34 118.4 0.8 1.1 1 0 0 1 1 1 1 4-alpha-L-fucosyltransferase glycosyl transferase group 56 DegT_DnrJ_EryC1 PF01041.17 AIM20128.1 - 4.5e-87 292.7 0.0 5.4e-87 292.4 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 AIM20128.1 - 6.7e-09 35.4 0.0 1e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 AIM20128.1 - 1.8e-07 30.4 0.0 2.5e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 AIM20128.1 - 0.00023 19.8 0.2 0.00035 19.2 0.2 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 AIM20128.1 - 0.0023 17.3 0.2 0.0073 15.6 0.2 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase cobW PF02492.19 AIM20129.1 - 2.1e-48 164.2 0.0 2.7e-48 163.9 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 AIM20129.1 - 1.6e-19 69.6 0.0 3.3e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_22 PF13401.6 AIM20129.1 - 0.0026 18.1 0.0 0.0047 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 AIM20129.1 - 0.0069 16.4 0.1 0.013 15.5 0.1 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 AIM20129.1 - 0.0075 16.2 0.0 1.6 8.6 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 AIM20129.1 - 0.019 15.5 0.2 0.21 12.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 AIM20129.1 - 0.026 14.4 0.0 0.067 13.1 0.0 1.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.6 AIM20129.1 - 0.026 14.7 0.1 0.28 11.3 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 AIM20129.1 - 0.043 14.2 0.1 0.075 13.4 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain Viral_helicase1 PF01443.18 AIM20129.1 - 0.05 13.3 0.0 0.072 12.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 AIM20129.1 - 0.061 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 AIM20129.1 - 0.068 12.1 0.0 0.16 10.9 0.0 1.7 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 AIM20129.1 - 0.075 13.3 0.1 0.4 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 AIM20129.1 - 0.084 12.6 0.0 3.5 7.4 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 AIM20129.1 - 0.11 12.4 4.4 0.58 10.1 0.1 2.7 3 1 0 3 3 3 0 NACHT domain ABC_tran PF00005.27 AIM20129.1 - 0.13 12.8 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Sel_put PF04328.13 AIM20130.1 - 7.7e-30 102.7 0.6 8.4e-30 102.6 0.6 1.0 1 0 0 1 1 1 1 Selenoprotein, putative CstA PF02554.14 AIM20131.1 - 5.5e-161 535.6 26.7 5.5e-161 535.6 26.7 2.3 3 0 0 3 3 3 1 Carbon starvation protein CstA CstA_5TM PF13722.6 AIM20131.1 - 2.8e-34 117.9 3.4 2.8e-34 117.9 3.4 3.0 3 0 0 3 3 3 1 5TM C-terminal transporter carbon starvation CstA Bac_luciferase PF00296.20 AIM20132.1 - 1.3e-68 231.7 0.3 1.6e-68 231.5 0.3 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase DUF1024 PF06260.12 AIM20132.1 - 0.14 12.5 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1024) LysR_substrate PF03466.20 AIM20133.1 - 8.4e-08 31.8 0.2 9.2e-08 31.7 0.2 1.0 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM20134.1 - 1.8e-17 63.0 0.1 3.3e-17 62.2 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 AIM20134.1 - 2.4e-12 46.7 0.0 3.7e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 LysR substrate binding domain MarR PF01047.22 AIM20134.1 - 0.017 15.0 0.1 0.039 13.9 0.1 1.5 1 0 0 1 1 1 0 MarR family RWP-RK PF02042.15 AIM20134.1 - 0.028 14.4 0.0 0.078 13.0 0.0 1.7 1 0 0 1 1 1 0 RWP-RK domain HTH_23 PF13384.6 AIM20134.1 - 0.061 13.1 0.0 0.22 11.4 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain HTH_6 PF01418.17 AIM20134.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family Arg_repressor PF01316.21 AIM20134.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain MgtC PF02308.16 AIM20135.1 - 1.5e-32 112.5 13.1 2e-32 112.1 13.1 1.2 1 0 0 1 1 1 1 MgtC family ABC_tran PF00005.27 AIM20136.1 - 3.2e-27 95.7 0.0 4.8e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIM20136.1 - 1.7e-07 31.3 1.0 0.0076 16.1 0.1 2.4 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 AIM20136.1 - 0.00064 19.7 0.3 0.0011 18.9 0.3 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 AIM20136.1 - 0.00084 19.0 0.1 0.0018 18.0 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AIM20136.1 - 0.013 15.9 0.1 0.016 15.6 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 AIM20136.1 - 0.015 15.5 0.1 0.25 11.5 0.1 2.4 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AIM20136.1 - 0.019 15.5 0.0 0.031 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 AIM20136.1 - 0.021 14.9 0.1 0.034 14.3 0.1 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain NACHT PF05729.12 AIM20136.1 - 0.034 14.1 0.0 0.08 12.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.23 AIM20136.1 - 0.091 12.8 0.1 0.23 11.6 0.1 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase ATPase_2 PF01637.18 AIM20136.1 - 0.15 11.9 0.1 3.4 7.5 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea G-alpha PF00503.20 AIM20136.1 - 0.2 10.8 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Porin_1 PF00267.21 AIM20137.1 - 1e-15 58.0 0.1 1.1e-15 57.9 0.1 1.0 1 0 0 1 1 1 1 Gram-negative porin Porin_1 PF00267.21 AIM20138.1 - 4.5e-59 200.6 3.3 5.3e-59 200.3 3.3 1.0 1 0 0 1 1 1 1 Gram-negative porin Porin_4 PF13609.6 AIM20138.1 - 1.4e-11 44.7 7.1 1.8e-11 44.4 7.1 1.0 1 0 0 1 1 1 1 Gram-negative porin ABC_tran PF00005.27 AIM20139.1 - 2e-30 106.1 0.0 3.2e-30 105.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIM20139.1 - 5.3e-06 26.5 0.3 0.11 12.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AIM20139.1 - 7e-05 23.3 0.0 0.0001 22.7 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AIM20139.1 - 0.00028 20.6 0.1 0.00055 19.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AIM20139.1 - 0.0013 19.0 0.7 0.015 15.6 0.1 2.5 1 1 1 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 AIM20139.1 - 0.0019 18.2 0.0 0.0032 17.4 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase NACHT PF05729.12 AIM20139.1 - 0.0097 15.8 0.2 0.051 13.5 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.6 AIM20139.1 - 0.031 13.8 0.7 0.084 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 AIM20139.1 - 0.086 12.9 0.1 0.23 11.6 0.0 1.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF87 PF01935.17 AIM20139.1 - 0.12 12.5 0.1 0.23 11.5 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain G-alpha PF00503.20 AIM20139.1 - 0.12 11.5 0.1 0.2 10.8 0.1 1.3 1 0 0 1 1 1 0 G-protein alpha subunit Mg_chelatase PF01078.21 AIM20139.1 - 0.13 11.6 0.1 0.25 10.7 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 AIM20139.1 - 0.15 12.5 0.0 0.25 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 AIM20139.1 - 0.15 10.8 0.5 6.7 5.4 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_30 PF13604.6 AIM20139.1 - 0.16 11.7 0.1 0.22 11.2 0.1 1.4 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 AIM20139.1 - 0.21 10.9 0.1 0.41 9.9 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin BPD_transp_1 PF00528.22 AIM20140.1 - 1.1e-29 103.5 41.7 1.8e-18 67.0 16.1 3.1 3 1 0 3 3 3 2 Binding-protein-dependent transport system inner membrane component DUF3754 PF12576.8 AIM20140.1 - 0.11 12.4 0.2 12 5.8 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3754) Glyco_transf_20 PF00982.21 AIM20141.1 - 4.9e-42 144.2 0.0 5.6e-42 144.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Acetyltransf_10 PF13673.7 AIM20142.1 - 0.00017 21.5 0.0 0.00021 21.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AIM20142.1 - 0.00024 21.3 0.0 0.00027 21.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AIM20142.1 - 0.0011 19.4 0.0 0.0013 19.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AIM20142.1 - 0.061 13.5 0.0 0.094 12.9 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FR47 PF08445.10 AIM20142.1 - 0.11 12.5 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 FR47-like protein Gln-synt_C PF00120.24 AIM20143.1 - 5.4e-82 275.6 0.0 6.6e-82 275.3 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain FANCF PF11107.8 AIM20143.1 - 0.0086 15.3 0.1 0.02 14.1 0.0 1.6 1 1 0 1 1 1 1 Fanconi anemia group F protein (FANCF) LysR_substrate PF03466.20 AIM20146.1 - 1.5e-41 142.1 3.5 2e-41 141.6 3.5 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM20146.1 - 1.8e-20 72.6 1.0 1.8e-20 72.6 1.0 1.8 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family PBP_like PF12727.7 AIM20146.1 - 0.00014 21.0 0.0 0.012 14.7 0.0 2.3 1 1 1 2 2 2 2 PBP superfamily domain CoA_trans PF01144.23 AIM20147.1 - 3.3e-69 232.6 0.4 3.9e-69 232.4 0.4 1.0 1 0 0 1 1 1 1 Coenzyme A transferase CoA_trans PF01144.23 AIM20148.1 - 4.4e-41 140.7 0.9 5e-41 140.5 0.9 1.0 1 0 0 1 1 1 1 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 AIM20148.1 - 1.2e-06 28.5 0.0 1.5e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Thiolase_N PF00108.23 AIM20149.1 - 2.8e-104 348.1 1.0 4.5e-104 347.4 1.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 AIM20149.1 - 5e-50 168.3 1.5 6.9e-50 167.8 0.6 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 AIM20149.1 - 1.5e-09 37.8 0.8 1.5e-09 37.8 0.8 2.8 3 1 1 4 4 4 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 AIM20149.1 - 0.0039 17.0 0.7 0.044 13.6 0.1 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.10 AIM20149.1 - 0.011 15.9 0.1 0.19 11.9 0.1 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Ribosomal_S11 PF00411.19 AIM20149.1 - 0.77 10.2 3.2 3 8.3 1.0 2.8 2 2 0 2 2 2 0 Ribosomal protein S11 3HCDH_N PF02737.18 AIM20150.1 - 2.2e-50 171.1 0.0 3e-50 170.6 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 AIM20150.1 - 3.8e-20 72.3 0.2 7.4e-20 71.4 0.2 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DAO PF01266.24 AIM20150.1 - 5.6e-05 22.9 0.2 7.2e-05 22.5 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.23 AIM20150.1 - 0.00019 21.4 0.0 0.00051 20.0 0.0 1.7 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 AIM20150.1 - 0.00049 20.3 0.0 0.0014 18.9 0.0 1.8 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 AIM20150.1 - 0.0016 19.0 0.0 0.0033 18.0 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent FAD_binding_2 PF00890.24 AIM20150.1 - 0.0067 15.5 0.2 0.014 14.5 0.2 1.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 AIM20150.1 - 0.055 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AIM20150.1 - 0.063 12.5 0.0 0.086 12.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HyaE PF07449.11 AIM20150.1 - 0.13 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE ApbA PF02558.16 AIM20150.1 - 0.17 11.5 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF3169 PF11368.8 AIM20151.1 - 0.023 14.2 3.2 0.99 8.9 0.0 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3169) adh_short_C2 PF13561.6 AIM20152.1 - 1.4e-53 181.8 0.5 2.6e-53 181.0 0.5 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AIM20152.1 - 1.1e-52 178.3 0.3 1.3e-52 178.1 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AIM20152.1 - 1.8e-08 34.5 0.6 2.6e-08 34.0 0.6 1.2 1 0 0 1 1 1 1 KR domain Porin_4 PF13609.6 AIM20153.1 - 6.2e-17 62.3 13.4 1e-16 61.6 13.4 1.5 1 1 0 1 1 1 1 Gram-negative porin DUF2490 PF10677.9 AIM20153.1 - 0.00077 19.5 2.3 0.022 14.7 0.2 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2490) Porin_2 PF02530.14 AIM20153.1 - 0.0017 17.7 4.7 0.031 13.6 0.1 2.6 2 1 0 2 2 2 2 Porin subfamily HTH_18 PF12833.7 AIM20154.1 - 2.6e-21 75.6 0.2 4.2e-21 75.0 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AIM20154.1 - 7e-12 45.1 0.1 1.4e-06 28.2 0.1 2.3 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family AraC_binding PF02311.19 AIM20154.1 - 6.2e-07 29.4 0.1 1.3e-06 28.3 0.1 1.5 1 1 0 1 1 1 1 AraC-like ligand binding domain Cupin_2 PF07883.11 AIM20154.1 - 0.00011 21.8 0.0 0.0002 21.0 0.0 1.4 1 0 0 1 1 1 1 Cupin domain DUF2875 PF11394.8 AIM20155.1 - 0.049 12.5 0.0 0.053 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2875) CbiG_mid PF11761.8 AIM20155.1 - 0.15 12.2 0.1 0.29 11.3 0.1 1.4 1 1 0 1 1 1 0 Cobalamin biosynthesis central region HTH_18 PF12833.7 AIM20156.1 - 9e-21 73.9 3.0 1.7e-20 73.1 3.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AIM20156.1 - 9.8e-15 54.2 0.6 1.1e-06 28.5 0.2 2.6 3 0 0 3 3 3 2 Bacterial regulatory helix-turn-helix proteins, AraC family GyrI-like PF06445.15 AIM20156.1 - 9.6e-11 42.2 0.0 1.7e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 GyrI-like small molecule binding domain Cass2 PF14526.6 AIM20156.1 - 9.3e-07 29.1 0.0 2.7e-06 27.6 0.0 1.8 1 1 0 1 1 1 1 Integron-associated effector binding protein MarR_2 PF12802.7 AIM20156.1 - 0.14 12.1 1.7 7.7 6.5 0.0 3.2 3 0 0 3 3 3 0 MarR family Ldt_C PF17969.1 AIM20157.1 - 1.9e-25 89.3 0.5 3.8e-25 88.4 0.5 1.5 1 0 0 1 1 1 1 L,D-transpeptidase C-terminal domain YkuD PF03734.14 AIM20157.1 - 1.3e-16 61.3 0.0 2.2e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain LysM PF01476.20 AIM20157.1 - 0.013 15.5 0.0 0.03 14.4 0.0 1.6 1 0 0 1 1 1 0 LysM domain TraT PF05818.12 AIM20158.1 - 0.1 12.3 4.9 0.098 12.3 4.9 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Bacteriocin_IIc PF10439.9 AIM20158.1 - 0.87 9.8 21.4 20 5.4 21.4 2.2 1 1 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide ExbD PF02472.16 AIM20159.1 - 8.3e-30 103.6 1.7 9.1e-30 103.5 1.7 1.0 1 0 0 1 1 1 1 Biopolymer transport protein ExbD/TolR TonB_N PF16031.5 AIM20160.1 - 6.2e-08 33.2 57.1 1.1e-07 32.4 57.1 1.3 1 0 0 1 1 1 1 TonB polyproline region TonB_C PF03544.14 AIM20160.1 - 8e-06 26.2 0.0 2e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Gram-negative bacterial TonB protein C-terminal TonB_2 PF13103.6 AIM20160.1 - 0.0093 16.2 0.0 0.0093 16.2 0.0 2.6 3 1 0 3 3 3 1 TonB C terminal DUF4386 PF14329.6 AIM20160.1 - 0.12 12.2 0.1 0.19 11.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4386) TonB_dep_Rec PF00593.24 AIM20161.1 - 2.2e-42 146.5 56.3 2.2e-42 146.5 56.3 1.6 1 1 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AIM20161.1 - 6.3e-12 46.0 0.9 1.8e-11 44.6 0.9 1.8 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain MotA_ExbB PF01618.16 AIM20162.1 - 2.3e-26 92.0 0.7 4.9e-26 90.9 0.7 1.5 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family DUF2298 PF10060.9 AIM20162.1 - 0.022 13.5 3.4 0.027 13.2 3.4 1.1 1 0 0 1 1 1 0 Uncharacterized membrane protein (DUF2298) PLDc_2 PF13091.6 AIM20163.1 - 9.2e-32 109.7 0.0 5.2e-15 55.5 0.0 2.3 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 AIM20163.1 - 1.9e-12 46.8 0.3 8.1e-05 22.6 0.1 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_3 PF13918.6 AIM20163.1 - 5.7e-05 22.8 0.0 8.5e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 PLD-like domain FAM83 PF07894.12 AIM20163.1 - 0.0014 18.2 0.0 0.0022 17.6 0.0 1.2 1 0 0 1 1 1 1 FAM83 A-H PP_kinase_C PF13090.6 AIM20163.1 - 0.022 14.2 0.0 6.8 6.1 0.0 2.3 2 1 0 2 2 2 0 Polyphosphate kinase C-terminal domain 2 Periviscerokin PF08259.11 AIM20163.1 - 0.079 13.2 0.1 0.2 12.0 0.1 1.7 1 0 0 1 1 1 0 Periviscerokinin family YdfA_immunity PF12127.8 AIM20163.1 - 0.14 11.2 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 SigmaW regulon antibacterial Peptidase_S58 PF03576.14 AIM20164.1 - 3.8e-106 355.0 2.5 4.4e-106 354.7 2.5 1.0 1 0 0 1 1 1 1 Peptidase family S58 AA_permease_2 PF13520.6 AIM20165.1 - 2.7e-34 118.7 44.3 3.2e-34 118.5 44.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 AIM20165.1 - 2.8e-13 49.3 42.7 3.7e-13 48.9 42.7 1.1 1 0 0 1 1 1 1 Amino acid permease Aldedh PF00171.22 AIM20166.1 - 1.8e-137 458.7 0.0 2.1e-137 458.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aminotran_3 PF00202.21 AIM20167.1 - 2.2e-86 290.0 0.0 2.5e-86 289.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 AIM20167.1 - 0.081 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase LysR_substrate PF03466.20 AIM20168.1 - 1.8e-20 73.2 0.3 2.6e-20 72.7 0.3 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM20168.1 - 2.6e-15 56.1 0.0 5e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_24 PF13412.6 AIM20168.1 - 0.0084 15.6 0.0 0.018 14.6 0.0 1.6 1 1 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 AIM20168.1 - 0.025 14.5 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 HTH domain FeoB_C PF07664.12 AIM20169.1 - 0.013 15.2 0.4 0.013 15.2 0.4 1.0 1 0 0 1 1 1 0 Ferrous iron transport protein B C terminus DUF202 PF02656.15 AIM20169.1 - 0.046 14.2 0.4 0.046 14.2 0.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF202) MFS_4 PF06779.14 AIM20169.1 - 0.086 12.1 0.6 0.078 12.3 0.6 1.0 1 0 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB Fe-ADH PF00465.19 AIM20170.1 - 2.8e-69 233.7 0.1 3.3e-69 233.4 0.1 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 AIM20170.1 - 1.9e-10 40.9 0.1 0.00013 21.8 0.9 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase GerE PF00196.19 AIM20171.1 - 1.8e-16 59.4 0.0 3e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AIM20171.1 - 2.5e-05 23.9 0.0 4.7e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AIM20171.1 - 0.00013 21.4 0.0 0.00038 19.9 0.0 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_24 PF13412.6 AIM20171.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DAO PF01266.24 AIM20172.1 - 2.3e-34 119.5 0.0 2.7e-34 119.3 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 AIM20172.1 - 1.3e-05 24.6 0.3 3.6e-05 23.1 0.2 1.7 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 AIM20172.1 - 1.4e-05 24.5 0.4 2.6e-05 23.6 0.4 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 AIM20172.1 - 6.9e-05 22.3 1.0 0.0057 16.0 1.0 2.7 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AIM20172.1 - 0.00047 19.4 1.3 0.00078 18.6 1.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 AIM20172.1 - 0.00083 19.9 0.8 0.22 12.1 0.5 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AIM20172.1 - 0.0016 17.7 0.2 0.0026 17.1 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 AIM20172.1 - 0.011 15.2 0.5 0.014 14.8 0.5 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AIM20172.1 - 0.075 13.3 2.1 0.2 11.9 1.6 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 AIM20172.1 - 0.086 11.9 1.1 0.16 11.0 1.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 AIM20172.1 - 0.18 10.4 0.3 0.76 8.4 0.2 1.9 2 0 0 2 2 2 0 HI0933-like protein Cupin_3 PF05899.12 AIM20173.1 - 1e-15 57.2 0.4 1.2e-15 56.9 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 AIM20173.1 - 0.00026 20.6 0.0 0.00037 20.1 0.0 1.2 1 0 0 1 1 1 1 Cupin domain PGDYG PF14083.6 AIM20173.1 - 0.087 13.1 0.1 0.37 11.1 0.1 1.9 2 0 0 2 2 2 0 PGDYG protein Cupin_6 PF12852.7 AIM20173.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 1 1 2 2 2 0 Cupin Hydrolase_4 PF12146.8 AIM20174.1 - 3.3e-57 193.5 0.1 4e-57 193.2 0.1 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AIM20174.1 - 5.4e-23 82.0 0.0 8.4e-21 74.8 0.1 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AIM20174.1 - 2e-15 58.0 5.5 2.3e-15 57.8 5.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 AIM20174.1 - 1.4e-08 34.4 0.0 0.00013 21.5 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Thioesterase PF00975.20 AIM20174.1 - 2.7e-07 30.9 0.1 3.6e-07 30.5 0.1 1.6 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.7 AIM20174.1 - 8.1e-06 25.7 0.0 0.00028 20.7 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 AIM20174.1 - 8.6e-05 22.4 0.1 0.00017 21.4 0.1 1.5 1 1 0 1 1 1 1 PGAP1-like protein DUF915 PF06028.11 AIM20174.1 - 0.00011 21.6 0.0 0.00027 20.4 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.25 AIM20174.1 - 0.00014 21.7 0.0 0.00024 21.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) VirJ PF06057.11 AIM20174.1 - 0.00022 21.2 0.0 0.00039 20.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Abhydrolase_3 PF07859.13 AIM20174.1 - 0.002 18.0 0.0 0.0027 17.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold LIDHydrolase PF10230.9 AIM20174.1 - 0.0032 17.1 0.0 0.0043 16.6 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase DUF3089 PF11288.8 AIM20174.1 - 0.0065 16.0 0.0 0.0089 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) FSH1 PF03959.13 AIM20174.1 - 0.0078 15.9 0.0 0.045 13.4 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Palm_thioest PF02089.15 AIM20174.1 - 0.01 15.7 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF3530 PF12048.8 AIM20174.1 - 0.011 15.2 0.0 0.022 14.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DLH PF01738.18 AIM20174.1 - 0.011 15.3 0.0 0.03 13.9 0.0 1.7 2 1 0 2 2 2 0 Dienelactone hydrolase family Esterase PF00756.20 AIM20174.1 - 0.012 15.3 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 0 Putative esterase UPF0227 PF05728.12 AIM20174.1 - 0.032 14.2 0.0 0.053 13.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Ndr PF03096.14 AIM20174.1 - 0.047 12.4 0.0 0.071 11.8 0.0 1.2 1 0 0 1 1 1 0 Ndr family Cutinase PF01083.22 AIM20174.1 - 0.051 13.5 0.0 0.077 12.9 0.0 1.2 1 0 0 1 1 1 0 Cutinase Ser_hydrolase PF06821.13 AIM20174.1 - 0.064 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_8 PF06259.12 AIM20174.1 - 0.066 12.8 0.0 0.17 11.5 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase DUF900 PF05990.12 AIM20174.1 - 0.14 11.7 0.0 0.28 10.6 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_2 PF02230.16 AIM20174.1 - 0.15 11.8 0.0 12 5.6 0.0 2.8 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Hist_deacetyl PF00850.19 AIM20175.1 - 2.8e-76 256.9 0.0 4.4e-76 256.3 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain MFS_1 PF07690.16 AIM20176.1 - 9.1e-08 31.4 70.0 0.00048 19.1 60.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fig1 PF12351.8 AIM20176.1 - 4.9 7.0 12.0 0.51 10.2 4.4 2.5 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 GerE PF00196.19 AIM20177.1 - 3.2e-14 52.2 1.0 3.2e-14 52.2 1.0 1.5 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AIM20177.1 - 7.5e-07 28.7 0.0 1.9e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 AIM20177.1 - 5.2e-05 22.9 0.2 0.00024 20.8 0.0 2.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_24 PF13412.6 AIM20177.1 - 8.9e-05 22.0 0.1 0.00026 20.5 0.1 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.16 AIM20177.1 - 0.00011 21.6 0.1 0.00026 20.4 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 AIM20177.1 - 0.0026 17.5 0.3 0.021 14.6 0.1 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_7 PF02796.15 AIM20177.1 - 0.0068 16.5 0.1 0.013 15.5 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_40 PF14493.6 AIM20177.1 - 0.007 16.8 0.0 0.043 14.3 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_10 PF04967.12 AIM20177.1 - 0.042 13.7 0.1 0.1 12.4 0.1 1.6 1 0 0 1 1 1 0 HTH DNA binding domain HTH_Tnp_ISL3 PF13542.6 AIM20177.1 - 0.053 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_29 PF13551.6 AIM20177.1 - 0.11 12.5 0.1 0.29 11.2 0.0 1.7 2 0 0 2 2 2 0 Winged helix-turn helix DUF3071 PF11268.8 AIM20177.1 - 0.12 12.5 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3071) DUF2089 PF09862.9 AIM20177.1 - 0.12 12.4 0.1 0.51 10.4 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2089) HTH_28 PF13518.6 AIM20177.1 - 0.15 12.2 0.3 0.5 10.5 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain DUF1324 PF07038.11 AIM20177.1 - 0.19 12.0 0.0 0.35 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1324) AA_permease_2 PF13520.6 AIM20178.1 - 1.3e-35 123.1 39.9 1.6e-35 122.7 39.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 AIM20178.1 - 3e-20 72.3 37.5 9.5e-20 70.6 37.6 1.8 1 1 0 1 1 1 1 Amino acid permease 2TM PF13239.6 AIM20178.1 - 3.3 8.1 10.8 11 6.4 2.0 3.6 2 2 0 2 2 2 0 2TM domain DUF3156 PF11354.8 AIM20179.1 - 6.9e-59 198.4 2.0 8.2e-59 198.1 2.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3156) adh_short_C2 PF13561.6 AIM20180.1 - 1.2e-52 178.9 0.2 1.7e-52 178.3 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AIM20180.1 - 1.5e-43 148.6 0.0 2e-43 148.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AIM20180.1 - 7.8e-09 35.7 0.2 1.4e-08 34.9 0.2 1.3 1 0 0 1 1 1 1 KR domain TrkA_N PF02254.18 AIM20180.1 - 0.0025 18.1 0.0 0.0048 17.2 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.17 AIM20180.1 - 0.005 17.4 0.4 0.011 16.3 0.4 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.6 AIM20180.1 - 0.0081 16.1 0.1 0.015 15.2 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Pyr_redox PF00070.27 AIM20180.1 - 0.017 15.7 0.4 0.034 14.7 0.4 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 AIM20180.1 - 0.072 12.3 0.5 0.11 11.8 0.5 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 AIM20180.1 - 0.21 11.6 0.1 0.36 10.9 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MoaF_C PF17409.2 AIM20181.1 - 1.2e-49 166.7 0.0 1.8e-49 166.1 0.0 1.3 1 0 0 1 1 1 1 MoaF C-terminal domain MoaF PF10703.9 AIM20181.1 - 1.2e-26 92.8 0.0 1.4e-25 89.3 0.0 2.1 2 0 0 2 2 2 1 MoaF N-terminal domain PA_decarbox PF05870.11 AIM20181.1 - 0.014 15.0 0.2 0.023 14.3 0.2 1.3 1 0 0 1 1 1 0 Phenolic acid decarboxylase (PAD) NRD1_2 PF01995.16 AIM20181.1 - 0.19 11.0 0.0 0.33 10.2 0.0 1.3 1 0 0 1 1 1 0 NrpR regulatory domains NRD1 and 2 adh_short_C2 PF13561.6 AIM20182.1 - 2.1e-65 220.5 3.9 2.8e-65 220.1 3.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AIM20182.1 - 2.7e-51 173.8 0.4 3.2e-51 173.6 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AIM20182.1 - 1.7e-13 50.9 1.1 2.4e-13 50.4 1.1 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 AIM20182.1 - 0.00037 20.7 0.0 0.00051 20.3 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain RmlD_sub_bind PF04321.17 AIM20182.1 - 0.0011 18.2 0.4 0.0018 17.4 0.4 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 AIM20182.1 - 0.0016 18.0 0.1 0.0026 17.3 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 AIM20182.1 - 0.015 14.3 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Arg_tRNA_synt_N PF03485.16 AIM20182.1 - 0.019 15.6 0.4 0.12 13.0 0.1 2.1 2 0 0 2 2 2 0 Arginyl tRNA synthetase N terminal domain MarR PF01047.22 AIM20183.1 - 1.8e-10 40.6 0.4 3e-10 39.9 0.4 1.4 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 AIM20183.1 - 2.3e-05 24.2 0.0 5e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 MarR family HxlR PF01638.17 AIM20183.1 - 0.01 15.6 0.1 0.016 15.0 0.1 1.4 1 0 0 1 1 1 0 HxlR-like helix-turn-helix TetR_C_35 PF18556.1 AIM20183.1 - 0.017 15.3 0.0 0.026 14.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial Tetracyclin repressor, C-terminal domain DUF3116 PF11313.8 AIM20183.1 - 0.078 12.8 0.1 0.13 12.1 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3116) FAA_hydrolase PF01557.18 AIM20184.1 - 2e-38 132.3 0.0 2.3e-38 132.1 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase PF01557.18 AIM20185.1 - 8.2e-62 208.7 0.0 1.1e-61 208.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Aldedh PF00171.22 AIM20186.1 - 6.6e-172 572.2 0.0 7.3e-172 572.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 AIM20186.1 - 0.068 12.6 0.0 0.74 9.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) LigB PF02900.18 AIM20187.1 - 3.1e-82 275.7 0.0 3.5e-82 275.6 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase CHMI PF02962.15 AIM20188.1 - 5.1e-50 169.0 0.0 5.7e-50 168.8 0.0 1.0 1 0 0 1 1 1 1 5-carboxymethyl-2-hydroxymuconate isomerase FAA_hydrolase PF01557.18 AIM20189.1 - 3.9e-06 26.7 0.0 4.7e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family HpcH_HpaI PF03328.14 AIM20190.1 - 1.3e-66 223.9 0.0 1.5e-66 223.7 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.21 AIM20190.1 - 0.00052 19.0 0.0 0.00067 18.6 0.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain MFS_1 PF07690.16 AIM20191.1 - 8.4e-50 169.7 43.2 3.1e-46 157.9 32.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AIM20191.1 - 2.1e-07 30.2 25.8 5e-07 29.0 25.8 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter ATG22 PF11700.8 AIM20191.1 - 4.2e-05 22.4 0.1 4.2e-05 22.4 0.1 4.0 1 1 2 4 4 4 2 Vacuole effluxer Atg22 like MFS_4 PF06779.14 AIM20191.1 - 5.4e-05 22.7 28.9 0.00027 20.4 9.9 2.1 1 1 1 2 2 2 2 Uncharacterised MFS-type transporter YbfB HTH_18 PF12833.7 AIM20192.1 - 1.3e-19 70.2 0.8 3.1e-19 69.0 0.8 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain AraC_binding PF02311.19 AIM20192.1 - 4.9e-07 29.7 2.0 1.3e-06 28.4 2.0 1.8 1 1 0 1 1 1 1 AraC-like ligand binding domain Cupin_2 PF07883.11 AIM20192.1 - 7.1e-05 22.5 0.1 0.00012 21.7 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 AIM20192.1 - 0.00072 19.3 2.1 0.041 13.6 0.6 2.2 1 1 0 2 2 2 2 Cupin HTH_AraC PF00165.23 AIM20192.1 - 0.00084 19.4 0.0 0.0053 16.8 0.1 2.2 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix proteins, AraC family AraC_binding_2 PF14525.6 AIM20192.1 - 0.0039 16.9 1.2 0.0039 16.9 1.2 1.6 2 0 0 2 2 2 1 AraC-binding-like domain HpaB_N PF11794.8 AIM20193.1 - 1.3e-92 310.4 0.0 1.6e-92 310.0 0.0 1.1 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal HpaB PF03241.13 AIM20193.1 - 3.4e-64 215.7 0.0 4.8e-64 215.2 0.0 1.2 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase C terminal Flavin_Reduct PF01613.18 AIM20194.1 - 4.3e-26 91.8 0.0 4.9e-26 91.6 0.0 1.0 1 0 0 1 1 1 1 Flavin reductase like domain MSP1b PF03429.13 AIM20194.1 - 0.076 11.1 0.0 0.083 11.0 0.0 1.1 1 0 0 1 1 1 0 Major surface protein 1B LytTR PF04397.15 AIM20194.1 - 0.14 12.4 0.1 0.38 11.0 0.0 1.7 2 0 0 2 2 2 0 LytTr DNA-binding domain Beta-lactamase PF00144.24 AIM20195.1 - 9.4e-63 212.4 2.7 1.2e-62 212.1 2.7 1.0 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 AIM20195.1 - 0.0021 17.5 0.0 0.0041 16.6 0.0 1.3 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase FCD PF07729.12 AIM20196.1 - 2.9e-22 79.4 7.6 2.9e-22 79.4 7.6 1.8 2 0 0 2 2 2 1 FCD domain GntR PF00392.21 AIM20196.1 - 1.3e-20 72.7 0.3 1.3e-20 72.7 0.3 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family Fe_dep_repress PF01325.19 AIM20196.1 - 0.00089 19.4 0.0 0.0015 18.7 0.0 1.4 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain LexA_DNA_bind PF01726.16 AIM20196.1 - 0.0022 17.7 0.0 0.0072 16.1 0.0 1.9 1 1 0 1 1 1 1 LexA DNA binding domain TrmB PF01978.19 AIM20196.1 - 0.026 14.4 0.0 0.064 13.2 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.10 AIM20196.1 - 0.026 14.3 0.0 0.062 13.1 0.0 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain TFIIE_alpha PF02002.17 AIM20196.1 - 0.032 14.1 0.0 0.098 12.5 0.0 1.7 1 0 0 1 1 1 0 TFIIE alpha subunit HTH_Crp_2 PF13545.6 AIM20196.1 - 0.033 14.2 0.1 0.075 13.0 0.1 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_11 PF08279.12 AIM20196.1 - 0.034 14.1 0.1 0.081 12.9 0.1 1.7 1 1 0 1 1 1 0 HTH domain Sigma70_r3 PF04539.16 AIM20196.1 - 0.092 12.9 0.6 0.48 10.6 0.0 2.2 2 0 0 2 2 2 0 Sigma-70 region 3 adh_short_C2 PF13561.6 AIM20197.1 - 3.2e-60 203.6 3.2 4.2e-60 203.2 3.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AIM20197.1 - 5.1e-46 156.6 0.8 7.2e-46 156.1 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AIM20197.1 - 2e-06 27.9 1.1 1.4e-05 25.1 1.1 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 AIM20197.1 - 0.00031 20.3 0.0 0.00095 18.7 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 AIM20197.1 - 0.0052 16.8 0.4 0.0087 16.0 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 AIM20197.1 - 0.12 11.7 0.3 0.2 11.0 0.1 1.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAA_hydrolase PF01557.18 AIM20198.1 - 6.9e-68 228.6 0.0 8.8e-68 228.2 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family GATase1_like PF07090.11 AIM20198.1 - 0.2 11.1 0.1 0.27 10.7 0.1 1.1 1 0 0 1 1 1 0 Putative glutamine amidotransferase MR_MLE_C PF13378.6 AIM20199.1 - 3.1e-58 196.9 0.3 4.7e-58 196.4 0.3 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 AIM20199.1 - 1.2e-05 25.5 0.0 2.3e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 AIM20199.1 - 0.00029 20.1 0.0 0.00053 19.2 0.0 1.4 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Amidohydro_2 PF04909.14 AIM20200.1 - 6.4e-33 114.8 10.0 7.3e-33 114.6 10.0 1.0 1 0 0 1 1 1 1 Amidohydrolase adh_short_C2 PF13561.6 AIM20201.1 - 2.2e-48 164.9 0.4 2.7e-48 164.6 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AIM20201.1 - 9.3e-38 129.6 0.8 1.2e-37 129.3 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AIM20201.1 - 1.1e-09 38.4 1.6 2.2e-09 37.5 1.6 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 AIM20201.1 - 0.001 18.6 0.1 0.0065 16.0 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RHH_5 PF07878.11 AIM20201.1 - 0.34 10.8 1.3 17 5.4 0.2 2.7 2 0 0 2 2 2 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 rhaM PF05336.13 AIM20202.1 - 2.7e-29 101.4 0.2 3.1e-29 101.2 0.2 1.0 1 0 0 1 1 1 1 L-rhamnose mutarotase MFS_1 PF07690.16 AIM20203.1 - 5.5e-26 91.3 47.3 3.9e-25 88.5 39.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AIM20203.1 - 0.00033 19.6 8.0 0.00033 19.6 8.0 3.2 1 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 AIM20203.1 - 0.13 10.5 23.5 0.0099 14.2 3.6 3.1 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 AIM20204.1 - 7.1e-34 117.3 65.6 1.1e-32 113.3 59.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 AIM20204.1 - 1.8e-05 24.3 45.7 2.1e-05 24.0 45.7 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB SLBB PF10531.9 AIM20204.1 - 0.16 11.9 0.8 0.36 10.7 0.1 1.9 2 0 0 2 2 2 0 SLBB domain LysR_substrate PF03466.20 AIM20205.1 - 8.9e-44 149.4 5.4 1.1e-43 149.0 5.4 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM20205.1 - 8e-17 61.0 1.3 1.4e-16 60.1 1.3 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 AIM20205.1 - 0.00062 19.6 1.5 0.0012 18.7 0.2 2.1 3 0 0 3 3 3 1 MarR family HTH_24 PF13412.6 AIM20205.1 - 0.06 12.9 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MFS_1 PF07690.16 AIM20206.1 - 9.2e-20 70.9 60.3 6.9e-10 38.4 35.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TetR_N PF00440.23 AIM20207.1 - 2.1e-13 49.8 0.3 3.7e-13 49.0 0.3 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family GGDEF PF00990.21 AIM20208.1 - 5.9e-46 156.2 0.0 7.6e-46 155.8 0.0 1.1 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain GGDEF_2 PF17853.1 AIM20208.1 - 7.8e-05 22.9 0.2 0.00014 22.1 0.2 1.3 1 0 0 1 1 1 1 GGDEF-like domain TipE PF16972.5 AIM20208.1 - 0.16 11.1 0.1 0.24 10.6 0.1 1.2 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE DUF1435 PF07256.12 AIM20209.1 - 5.4e-33 112.9 7.8 8.6e-33 112.3 7.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1435) LysR_substrate PF03466.20 AIM20210.1 - 2.1e-41 141.6 3.4 3e-41 141.1 3.4 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM20210.1 - 4.4e-19 68.2 2.5 7.8e-19 67.4 2.5 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AIM20210.1 - 0.00083 19.1 0.4 0.002 17.9 0.4 1.6 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain MarR_2 PF12802.7 AIM20210.1 - 0.002 18.0 0.1 0.0065 16.3 0.1 1.8 1 0 0 1 1 1 1 MarR family HTH_IclR PF09339.10 AIM20210.1 - 0.014 15.2 2.6 0.075 12.8 0.1 3.1 3 0 0 3 3 3 0 IclR helix-turn-helix domain HTH_8 PF02954.19 AIM20210.1 - 0.037 13.8 0.1 0.091 12.6 0.1 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family HTH_23 PF13384.6 AIM20210.1 - 0.055 13.3 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_20 PF12840.7 AIM20210.1 - 0.075 13.1 0.1 0.26 11.4 0.1 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_28 PF13518.6 AIM20210.1 - 0.082 13.1 0.3 0.29 11.3 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain MarR PF01047.22 AIM20210.1 - 0.086 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 MarR family Aldo_ket_red PF00248.21 AIM20211.1 - 7.4e-85 284.7 0.0 8.8e-85 284.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MTS PF05175.14 AIM20212.1 - 1.2e-59 200.6 0.0 1.9e-59 200.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain MTS_N PF08468.11 AIM20212.1 - 1.3e-53 181.3 0.0 2.5e-53 180.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain N-terminal PrmA PF06325.13 AIM20212.1 - 1.3e-08 34.6 0.0 2e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 AIM20212.1 - 1.9e-08 34.9 0.1 7.5e-08 33.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 AIM20212.1 - 2.4e-08 33.9 0.0 5e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIM20212.1 - 2.9e-06 27.9 0.0 1e-05 26.2 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AIM20212.1 - 0.00027 20.8 0.0 0.00048 20.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AIM20212.1 - 0.00089 19.9 0.1 0.017 15.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 AIM20212.1 - 0.00092 18.6 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.11 AIM20212.1 - 0.002 17.8 0.0 0.0041 16.7 0.0 1.5 2 0 0 2 2 2 1 Nodulation protein S (NodS) Methyltransf_10 PF05971.12 AIM20212.1 - 0.003 16.9 0.0 0.007 15.7 0.0 1.5 1 1 0 1 1 1 1 RNA methyltransferase FmrO PF07091.11 AIM20212.1 - 0.0039 16.8 0.0 0.0061 16.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) PCMT PF01135.19 AIM20212.1 - 0.0045 16.8 0.2 0.0068 16.2 0.2 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 AIM20212.1 - 0.006 16.5 0.0 0.0093 15.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 AIM20212.1 - 0.013 15.2 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 DUF938 PF06080.12 AIM20212.1 - 0.013 15.3 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_2 PF00891.18 AIM20212.1 - 0.017 14.4 0.0 0.027 13.7 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Cons_hypoth95 PF03602.15 AIM20212.1 - 0.043 13.5 0.0 0.07 12.8 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_16 PF10294.9 AIM20212.1 - 0.044 13.5 0.3 0.075 12.8 0.3 1.3 1 0 0 1 1 1 0 Lysine methyltransferase GidB PF02527.15 AIM20212.1 - 0.059 12.7 0.1 0.091 12.1 0.1 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_32 PF13679.6 AIM20212.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 AIM20212.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB DUF1298 PF06974.13 AIM20212.1 - 0.16 11.9 0.1 1.8 8.5 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1298) DNA_III_psi PF03603.13 AIM20213.1 - 1.7e-47 160.8 0.0 1.9e-47 160.6 0.0 1.0 1 0 0 1 1 1 1 DNA polymerase III psi subunit Inhibitor_I66 PF16850.5 AIM20213.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase inhibitor I66 CSTF_C PF14304.6 AIM20213.1 - 0.26 10.9 0.1 0.26 10.9 0.1 2.4 4 0 0 4 4 4 0 Transcription termination and cleavage factor C-terminal Acetyltransf_1 PF00583.25 AIM20214.1 - 4.8e-18 65.5 0.0 6e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 AIM20214.1 - 8.8e-14 51.2 0.1 1.2e-13 50.9 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 AIM20214.1 - 1.4e-12 47.7 0.0 1.7e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AIM20214.1 - 1.4e-11 44.6 0.0 1.8e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AIM20214.1 - 6.8e-08 32.8 0.0 8.1e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AIM20214.1 - 1.9e-06 28.6 0.0 3.2e-06 27.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 AIM20214.1 - 1.9e-06 27.6 0.0 2e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_9 PF13527.7 AIM20214.1 - 0.00025 21.1 0.0 0.00046 20.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 AIM20214.1 - 0.00067 19.4 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DNA_photolyase PF00875.18 AIM20214.1 - 0.0025 17.8 0.0 0.0033 17.4 0.0 1.1 1 0 0 1 1 1 1 DNA photolyase Acetyltransf_6 PF13480.7 AIM20214.1 - 0.0055 16.9 0.0 0.0074 16.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain HTH_13 PF11972.8 AIM20214.1 - 0.037 14.1 0.0 0.081 13.0 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain GNAT_acetyltr_2 PF13718.6 AIM20214.1 - 0.11 11.9 0.0 0.14 11.6 0.0 1.3 1 1 0 1 1 1 0 GNAT acetyltransferase 2 Acetyltransf_15 PF17013.5 AIM20214.1 - 0.15 11.6 0.0 0.28 10.6 0.0 1.4 1 1 0 1 1 1 0 Putative acetyl-transferase MOZ_SAS PF01853.18 AIM20214.1 - 0.17 11.5 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 MOZ/SAS family GTP_EFTU PF00009.27 AIM20215.1 - 2.4e-46 157.7 0.0 3.4e-46 157.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RF3_C PF16658.5 AIM20215.1 - 4.6e-46 155.9 0.0 8e-46 155.1 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain GTP_EFTU_D2 PF03144.25 AIM20215.1 - 7.9e-12 45.4 0.4 2.5e-11 43.8 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 AIM20215.1 - 4.8e-05 23.4 0.0 9.8e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 AIM20215.1 - 0.001 19.1 0.0 0.002 18.2 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II Ras PF00071.22 AIM20215.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Ras family BON PF04972.17 AIM20216.1 - 1.4e-39 134.2 17.0 3.1e-20 72.3 4.6 2.4 2 0 0 2 2 2 2 BON domain HMA PF00403.26 AIM20216.1 - 3.5 8.2 7.7 2.5 8.6 0.8 3.1 2 2 1 3 3 3 0 Heavy-metal-associated domain DUF1328 PF07043.13 AIM20217.1 - 9.1e-13 48.2 21.0 1.1e-12 48.0 21.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1328) ThrE PF06738.12 AIM20217.1 - 0.044 13.2 6.0 0.046 13.1 6.0 1.0 1 0 0 1 1 1 0 Putative threonine/serine exporter Pox_A14 PF05767.12 AIM20217.1 - 0.086 13.0 4.7 0.099 12.8 4.7 1.1 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 Phage_holin_3_6 PF07332.11 AIM20217.1 - 0.57 10.2 12.3 0.75 9.8 12.3 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Tmemb_55A PF09788.9 AIM20217.1 - 0.66 9.0 1.3 0.72 8.9 1.3 1.0 1 0 0 1 1 1 0 Transmembrane protein 55A DUF2721 PF11026.8 AIM20217.1 - 1.1 9.1 8.7 1.3 8.9 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Orai-1 PF07856.12 AIM20217.1 - 1.2 8.8 4.9 1.2 8.8 4.9 1.0 1 0 0 1 1 1 0 Mediator of CRAC channel activity MttA_Hcf106 PF02416.16 AIM20217.1 - 3 7.2 7.3 4.8 6.6 1.3 2.1 2 0 0 2 2 2 0 mttA/Hcf106 family DUF4389 PF14333.6 AIM20217.1 - 3.7 7.5 7.6 26 4.8 7.6 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4389) DUF2207 PF09972.9 AIM20217.1 - 4.5 5.9 8.7 4.4 5.9 8.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF202 PF02656.15 AIM20217.1 - 6.7 7.2 11.5 14 6.2 11.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF202) RCR PF12273.8 AIM20217.1 - 7.9 7.2 5.4 2.9 8.6 0.7 1.9 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red CsbD PF05532.12 AIM20218.1 - 1.4e-07 31.3 0.0 1.6e-07 31.1 0.0 1.0 1 0 0 1 1 1 1 CsbD-like Patatin PF01734.22 AIM20219.1 - 8.4e-23 81.6 0.3 1.7e-22 80.6 0.3 1.5 1 1 0 1 1 1 1 Patatin-like phospholipase TatD_DNase PF01026.21 AIM20220.1 - 5e-67 225.9 0.0 5.9e-67 225.7 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase NBD_C PF17042.5 AIM20220.1 - 0.044 14.3 0.3 0.084 13.4 0.3 1.5 1 0 0 1 1 1 0 Nucleotide-binding C-terminal domain Asparaginase_C PF17763.1 AIM20220.1 - 0.051 13.8 0.0 0.096 12.9 0.0 1.4 1 0 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain Nucleos_tra2_C PF07662.13 AIM20221.1 - 8.7e-80 267.4 6.2 8.7e-80 267.4 6.2 1.9 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 AIM20221.1 - 2.8e-23 82.3 6.5 2.8e-23 82.3 6.5 3.0 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 AIM20221.1 - 2.3e-08 34.3 4.6 2.3e-08 34.3 4.6 3.3 3 1 0 3 3 3 1 Nucleoside recognition DeoC PF01791.9 AIM20222.1 - 5e-47 160.5 0.6 5.6e-47 160.3 0.6 1.0 1 0 0 1 1 1 1 DeoC/LacD family aldolase Glycos_transf_3 PF00591.21 AIM20223.1 - 9.5e-51 172.8 1.6 1.5e-50 172.2 1.6 1.3 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain PYNP_C PF07831.13 AIM20223.1 - 2.3e-24 84.8 0.1 4.7e-24 83.8 0.1 1.6 1 0 0 1 1 1 1 Pyrimidine nucleoside phosphorylase C-terminal domain Glycos_trans_3N PF02885.17 AIM20223.1 - 1.1e-18 66.8 0.0 3e-18 65.4 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Metalloenzyme PF01676.18 AIM20224.1 - 7.6e-36 123.7 0.0 1.6e-35 122.6 0.0 1.5 1 1 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 AIM20224.1 - 0.049 13.0 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 Sulfatase PNP_UDP_1 PF01048.20 AIM20225.1 - 7.2e-37 126.9 2.2 8.5e-37 126.6 2.2 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Transketolase_C PF02780.20 AIM20225.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Transketolase, C-terminal domain YidD PF01809.18 AIM20225.1 - 0.14 12.0 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Putative membrane protein insertion efficiency factor SMP_2 PF10144.9 AIM20226.1 - 9.1e-68 226.9 0.3 1.3e-67 226.4 0.3 1.2 1 0 0 1 1 1 1 Bacterial virulence factor haemolysin TetR_C_16 PF17920.1 AIM20226.1 - 0.0067 16.6 0.3 2.3 8.5 0.1 2.2 2 0 0 2 2 2 2 Tetracyclin repressor-like, C-terminal domain DUF3290 PF11694.8 AIM20226.1 - 0.0099 15.9 2.3 0.064 13.2 0.4 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3290) Sigma_reg_N PF13800.6 AIM20226.1 - 0.091 13.1 0.6 0.63 10.4 0.2 2.1 2 0 0 2 2 2 0 Sigma factor regulator N-terminal OPA3 PF07047.12 AIM20226.1 - 0.13 12.0 0.0 1.6 8.5 0.0 2.1 2 0 0 2 2 2 0 Optic atrophy 3 protein (OPA3) GspL_C PF12693.7 AIM20226.1 - 3.6 7.4 5.6 5.8 6.7 0.7 2.2 2 0 0 2 2 2 0 GspL periplasmic domain DUF5609 PF18429.1 AIM20227.1 - 2.9e-20 71.8 0.0 6.3e-20 70.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5609) Hydrolase PF00702.26 AIM20227.1 - 3.8e-16 60.0 1.4 3.3e-15 56.9 0.8 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AIM20227.1 - 2.9e-15 57.2 0.3 1.9e-14 54.5 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AIM20227.1 - 1.3e-12 48.0 0.1 1.3e-11 44.8 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 AIM20227.1 - 0.00088 18.9 0.0 0.0031 17.1 0.0 1.8 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase HAD_2 PF13419.6 AIM20227.1 - 0.0027 17.8 0.0 0.29 11.2 0.0 2.2 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 AIM20227.1 - 0.011 15.2 0.0 0.05 13.0 0.0 1.8 2 0 0 2 2 2 0 Putative Phosphatase Hydrolase_like PF13242.6 AIM20227.1 - 0.035 14.2 0.1 0.079 13.0 0.1 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like ATPase PF06745.13 AIM20228.1 - 4.5e-16 58.9 0.1 1.6e-09 37.5 0.1 2.1 1 1 1 2 2 2 2 KaiC AAA_25 PF13481.6 AIM20228.1 - 4.2e-14 52.6 0.1 1.6e-13 50.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain Rubredoxin_2 PF18073.1 AIM20228.1 - 1.5e-12 47.0 6.0 2.5e-12 46.3 6.0 1.4 1 0 0 1 1 1 1 Rubredoxin metal binding domain ChlI PF13541.6 AIM20228.1 - 1.1e-09 38.2 0.0 2.6e-09 37.0 0.0 1.7 2 0 0 2 2 1 1 Subunit ChlI of Mg-chelatase Lon_C PF05362.13 AIM20228.1 - 4.3e-07 29.7 0.1 9.5e-07 28.5 0.1 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain DnaB_C PF03796.15 AIM20228.1 - 5.1e-07 29.3 0.2 0.0007 19.0 0.0 2.2 2 0 0 2 2 2 2 DnaB-like helicase C terminal domain Rad51 PF08423.11 AIM20228.1 - 3.5e-06 26.5 0.5 0.0041 16.4 0.1 2.2 2 0 0 2 2 2 2 Rad51 RecA PF00154.21 AIM20228.1 - 0.00046 19.7 0.2 0.00074 19.1 0.2 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein GvpD PF07088.11 AIM20228.1 - 0.00077 18.2 0.0 0.023 13.3 0.0 2.1 1 1 0 2 2 2 1 GvpD gas vesicle protein DUF2075 PF09848.9 AIM20228.1 - 0.00083 18.7 0.1 0.0017 17.7 0.1 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 AIM20228.1 - 0.0011 19.2 0.1 0.0023 18.2 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AIM20228.1 - 0.0019 18.6 0.2 0.0052 17.2 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 AIM20228.1 - 0.0027 18.2 0.0 0.0054 17.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_24 PF13479.6 AIM20228.1 - 0.0028 17.4 0.0 0.0047 16.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 AIM20228.1 - 0.0032 17.9 0.0 0.0066 16.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 AIM20228.1 - 0.0047 16.9 0.3 0.018 14.9 0.1 2.1 1 1 1 2 2 2 1 NTPase Zeta_toxin PF06414.12 AIM20228.1 - 0.0063 15.8 0.1 0.012 15.0 0.1 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_14 PF13173.6 AIM20228.1 - 0.0092 16.0 0.0 0.017 15.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 AIM20228.1 - 0.011 15.3 0.1 0.017 14.7 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 AIM20228.1 - 0.049 13.6 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 AIM20228.1 - 0.072 12.8 0.2 0.17 11.7 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 AIM20228.1 - 0.11 12.5 0.7 1.1 9.2 0.7 2.2 1 1 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 AIM20228.1 - 0.13 12.0 0.7 0.52 10.0 0.2 2.2 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 AIM20228.1 - 0.13 12.3 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Viral_helicase1 PF01443.18 AIM20228.1 - 0.16 11.7 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.6 AIM20229.1 - 1.6e-31 109.7 0.0 2.6e-31 109.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain HTH_3 PF01381.22 AIM20229.1 - 3.4e-06 27.0 0.0 1.3e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix HTH_31 PF13560.6 AIM20229.1 - 7.1e-05 23.1 0.0 0.00017 21.8 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain CTP_transf_like PF01467.26 AIM20229.1 - 0.00038 20.6 0.1 0.0009 19.5 0.1 1.8 1 1 0 1 1 1 1 Cytidylyltransferase-like Citrate_ly_lig PF08218.11 AIM20229.1 - 0.00065 19.4 0.0 0.008 15.9 0.0 2.5 3 0 0 3 3 3 1 Citrate lyase ligase C-terminal domain HTH_19 PF12844.7 AIM20229.1 - 0.01 15.8 0.0 0.048 13.7 0.0 2.1 2 1 0 2 2 2 0 Helix-turn-helix domain MMR_HSR1 PF01926.23 AIM20229.1 - 0.024 14.7 0.3 0.042 13.9 0.3 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 AIM20229.1 - 0.074 13.4 0.3 0.53 10.6 0.3 2.3 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 AIM20229.1 - 0.076 13.5 0.0 0.4 11.2 0.0 2.1 3 0 0 3 3 3 0 ABC transporter AAA_29 PF13555.6 AIM20229.1 - 0.093 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FAD_syn PF06574.12 AIM20229.1 - 0.1 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 FAD synthetase HTH_26 PF13443.6 AIM20229.1 - 0.14 12.6 0.0 0.27 11.7 0.0 1.5 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Dynamin_N PF00350.23 AIM20229.1 - 0.22 11.6 0.4 0.4 10.7 0.4 1.4 1 0 0 1 1 1 0 Dynamin family PMT_2 PF13231.6 AIM20230.1 - 6.4e-16 59.0 20.0 6.4e-16 59.0 20.0 2.6 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase ADH_zinc_N_2 PF13602.6 AIM20231.1 - 3.5e-19 70.2 0.0 5.4e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AIM20231.1 - 3.1e-08 33.5 0.0 5.7e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AIM20231.1 - 2.3e-07 30.8 0.0 3.6e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase LysR_substrate PF03466.20 AIM20232.1 - 4.8e-45 153.5 4.4 7e-45 153.0 4.4 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM20232.1 - 3.9e-20 71.6 1.4 9.2e-20 70.4 1.4 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AIM20232.1 - 0.00017 21.3 0.1 0.00055 19.7 0.1 1.9 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_IclR PF09339.10 AIM20232.1 - 0.0055 16.5 0.6 0.033 14.0 0.1 2.4 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_20 PF12840.7 AIM20232.1 - 0.0058 16.7 0.1 0.013 15.5 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 AIM20232.1 - 0.0099 16.0 0.0 0.038 14.1 0.0 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 AIM20232.1 - 0.017 15.0 0.2 0.068 13.1 0.1 2.1 2 0 0 2 2 2 0 MarR family HTH_24 PF13412.6 AIM20232.1 - 0.029 13.9 0.0 0.058 13.0 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 AIM20232.1 - 0.045 13.6 0.1 0.16 11.9 0.0 2.0 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 AIM20232.1 - 0.05 13.0 0.1 0.24 10.9 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Cupin_6 PF12852.7 AIM20233.1 - 1.6e-32 112.7 1.7 2.4e-32 112.2 1.7 1.3 1 0 0 1 1 1 1 Cupin HTH_18 PF12833.7 AIM20233.1 - 1.6e-20 73.2 0.9 5.2e-20 71.5 0.7 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 AIM20233.1 - 2.5e-15 56.1 0.0 3.3e-07 30.2 0.0 2.5 3 0 0 3 3 3 2 Bacterial regulatory helix-turn-helix proteins, AraC family TetR_N PF00440.23 AIM20233.1 - 0.0099 15.6 0.1 0.025 14.4 0.1 1.7 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family DAP_B PF07930.12 AIM20233.1 - 0.11 12.4 0.2 0.2 11.6 0.2 1.3 1 0 0 1 1 1 0 D-aminopeptidase, domain B HTH_6 PF01418.17 AIM20233.1 - 0.18 11.8 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family HTH_23 PF13384.6 AIM20233.1 - 0.22 11.4 1.0 13 5.7 0.1 2.5 1 1 1 2 2 2 0 Homeodomain-like domain ABC_tran PF00005.27 AIM20234.1 - 7.1e-58 195.0 0.1 5.2e-31 108.0 0.0 2.7 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 AIM20234.1 - 1.8e-16 60.9 3.8 8.7e-05 22.5 0.0 4.3 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 AIM20234.1 - 5.4e-13 48.8 8.1 8.4e-12 45.0 2.3 2.5 2 0 0 2 2 2 1 ABC transporter AAA_23 PF13476.6 AIM20234.1 - 8.5e-07 29.7 2.6 0.0053 17.3 0.0 3.1 3 1 1 4 4 4 2 AAA domain SMC_N PF02463.19 AIM20234.1 - 1.1e-06 28.3 0.4 0.41 10.0 0.0 4.0 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 AIM20234.1 - 9.5e-06 25.7 0.3 0.071 13.2 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 AIM20234.1 - 1.6e-05 24.6 0.9 0.024 14.4 0.1 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AIM20234.1 - 0.00037 20.4 0.1 0.089 12.7 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 AIM20234.1 - 0.0011 19.1 0.0 0.79 9.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 AIM20234.1 - 0.0016 18.7 1.2 0.41 10.9 0.0 3.2 2 2 0 2 2 2 1 AAA domain AAA_27 PF13514.6 AIM20234.1 - 0.0017 18.0 0.0 0.4 10.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 AIM20234.1 - 0.0025 18.4 0.8 3.4 8.2 0.2 3.4 3 1 0 3 3 3 1 AAA domain MeaB PF03308.16 AIM20234.1 - 0.0028 16.7 0.3 1.4 7.8 0.1 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB SbcCD_C PF13558.6 AIM20234.1 - 0.0054 16.9 0.9 4.1 7.7 0.0 4.0 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 AIM20234.1 - 0.0057 17.1 8.1 3.4 8.0 0.0 3.6 2 1 0 3 3 2 2 AAA ATPase domain AAA_24 PF13479.6 AIM20234.1 - 0.0091 15.7 0.2 1.5 8.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 AIM20234.1 - 0.0099 15.5 0.4 0.76 9.3 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ATP-synt_ab PF00006.25 AIM20234.1 - 0.029 14.0 0.1 0.21 11.2 0.0 2.0 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain SRP54 PF00448.22 AIM20234.1 - 0.041 13.5 0.3 1.4 8.5 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Arf PF00025.21 AIM20234.1 - 0.045 13.2 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family Dynamin_N PF00350.23 AIM20234.1 - 0.049 13.7 0.0 2.9 7.9 0.0 2.6 2 0 0 2 2 2 0 Dynamin family NB-ARC PF00931.22 AIM20234.1 - 0.066 12.4 0.9 2.1 7.5 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain Roc PF08477.13 AIM20234.1 - 0.071 13.3 1.2 4.2 7.6 0.0 2.8 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase HAUS4 PF14735.6 AIM20234.1 - 0.089 12.5 0.3 0.17 11.6 0.3 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 AAA_25 PF13481.6 AIM20234.1 - 0.09 12.3 1.5 14 5.2 0.0 3.7 4 1 0 4 4 4 0 AAA domain DLIC PF05783.11 AIM20234.1 - 0.14 10.9 0.1 6.2 5.5 0.0 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) AAA_15 PF13175.6 AIM20234.1 - 0.15 11.8 0.5 5.7 6.5 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain AAA_14 PF13173.6 AIM20234.1 - 0.16 12.0 0.0 7.5 6.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_13 PF13166.6 AIM20234.1 - 0.22 10.1 6.0 3.2 6.3 0.1 2.9 3 1 0 3 3 2 0 AAA domain AAA_28 PF13521.6 AIM20234.1 - 0.86 9.8 4.6 5.9 7.1 0.0 3.1 3 1 0 3 3 2 0 AAA domain Jnk-SapK_ap_N PF09744.9 AIM20234.1 - 3.3 7.9 11.7 4.7 7.4 0.6 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 OmpA PF00691.20 AIM20235.1 - 3.2e-18 65.9 0.0 4.7e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 OmpA family Pilus_CpaD PF09476.10 AIM20235.1 - 0.0019 18.0 0.0 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 Pilus biogenesis CpaD protein (pilus_cpaD) LPAM_1 PF08139.12 AIM20235.1 - 0.12 12.9 3.5 0.25 11.9 3.5 1.5 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site MLTD_N PF06474.12 AIM20235.1 - 0.34 11.1 5.4 0.74 10.0 4.6 2.1 2 1 0 2 2 2 0 MltD lipid attachment motif GGDEF PF00990.21 AIM20236.1 - 3.7e-46 156.8 0.0 5.5e-46 156.2 0.0 1.2 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain CHASE8 PF17152.4 AIM20236.1 - 1.5e-29 102.2 0.0 3.1e-29 101.2 0.0 1.5 1 0 0 1 1 1 1 Periplasmic sensor domain dCache_3 PF14827.6 AIM20236.1 - 0.15 11.7 0.0 0.37 10.4 0.0 1.6 1 0 0 1 1 1 0 Double sensory domain of two-component sensor kinase DUF4154 PF13689.6 AIM20237.1 - 3e-29 102.1 0.0 3.8e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 YfiR/HmsC-like SLT PF01464.20 AIM20238.1 - 3e-33 113.9 0.1 5.3e-33 113.2 0.1 1.3 1 0 0 1 1 1 1 Transglycosylase SLT domain SLT_L PF14718.6 AIM20238.1 - 5.9e-24 84.0 0.8 5.9e-24 84.0 0.8 2.9 3 0 0 3 3 3 1 Soluble lytic murein transglycosylase L domain Cucumo_coat PF00760.18 AIM20238.1 - 0.0093 15.6 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Cucumovirus coat protein Trp_repressor PF01371.19 AIM20239.1 - 1.3e-30 105.4 0.2 1.5e-30 105.2 0.2 1.0 1 0 0 1 1 1 1 Trp repressor protein DUF3426 PF11906.8 AIM20239.1 - 0.01 16.0 0.4 0.07 13.3 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3426) HTH_5 PF01022.20 AIM20239.1 - 0.012 15.4 0.1 0.075 12.9 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family NTPase_I-T PF01931.18 AIM20240.1 - 1.4e-44 151.8 0.1 1.5e-44 151.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF84 DUF2700 PF10912.8 AIM20240.1 - 0.13 12.3 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2700) His_Phos_1 PF00300.22 AIM20241.1 - 1.4e-55 188.0 0.5 1.6e-55 187.8 0.5 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) GyrI-like PF06445.15 AIM20242.1 - 3.1e-22 79.6 0.0 4.1e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 GyrI-like small molecule binding domain HTH_18 PF12833.7 AIM20242.1 - 4.8e-20 71.6 1.9 7.6e-20 71.0 1.9 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AIM20242.1 - 4.3e-15 55.4 0.3 1.8e-07 31.1 0.3 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Cass2 PF14526.6 AIM20242.1 - 9.9e-12 45.3 0.0 1.9e-11 44.4 0.0 1.4 2 0 0 2 2 2 1 Integron-associated effector binding protein CreA PF05981.12 AIM20243.1 - 1.2e-57 193.5 0.0 1.4e-57 193.3 0.0 1.0 1 0 0 1 1 1 1 CreA protein Response_reg PF00072.24 AIM20244.1 - 1.8e-27 95.7 0.3 6e-27 94.0 0.1 1.8 2 0 0 2 2 2 1 Response regulator receiver domain Trans_reg_C PF00486.28 AIM20244.1 - 2.5e-18 65.9 0.0 4.7e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal SpoU_methylase PF00588.19 AIM20245.1 - 2.4e-34 118.5 0.0 3.2e-34 118.1 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family Homoserine_dh PF00742.19 AIM20246.1 - 6.1e-48 163.0 0.0 2.7e-47 160.9 0.0 2.1 2 0 0 2 2 2 1 Homoserine dehydrogenase AA_kinase PF00696.28 AIM20246.1 - 2.7e-45 154.8 0.1 8.3e-45 153.2 0.1 1.9 1 0 0 1 1 1 1 Amino acid kinase family NAD_binding_3 PF03447.16 AIM20246.1 - 2.9e-29 102.1 0.0 7.5e-29 100.8 0.0 1.8 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ACT_7 PF13840.6 AIM20246.1 - 1.7e-19 69.3 1.4 3.7e-09 36.2 0.0 2.6 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 AIM20246.1 - 1.3e-18 66.5 0.6 4e-09 36.1 0.0 2.7 2 0 0 2 2 2 2 ACT domain ACT_6 PF13740.6 AIM20246.1 - 0.12 12.3 0.8 6.3 6.9 0.2 2.8 2 0 0 2 2 2 0 ACT domain GHMP_kinases_N PF00288.26 AIM20247.1 - 2.5e-14 53.2 0.1 6.5e-14 51.9 0.1 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 AIM20247.1 - 3.3e-10 40.2 2.2 4.1e-10 39.9 0.0 2.3 3 0 0 3 3 3 1 GHMP kinases C terminal PALP PF00291.25 AIM20248.1 - 1.3e-25 90.4 0.0 1.9e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_synth_N PF14821.6 AIM20248.1 - 9.8e-12 44.9 0.0 3.3e-11 43.2 0.0 1.9 1 0 0 1 1 1 1 Threonine synthase N terminus H2O2_YaaD PF03883.14 AIM20249.1 - 3.8e-91 304.7 0.0 4.3e-91 304.6 0.0 1.0 1 0 0 1 1 1 1 Peroxide stress protein YaaA Na_Ala_symp PF01235.17 AIM20250.1 - 7e-160 532.6 21.5 8.7e-160 532.3 21.5 1.0 1 0 0 1 1 1 1 Sodium:alanine symporter family TAL_FSA PF00923.19 AIM20251.1 - 8.4e-101 337.1 0.0 9.4e-101 336.9 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Mononeg_mRNAcap PF14318.6 AIM20251.1 - 0.15 11.3 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Mononegavirales mRNA-capping region V MoCF_biosynth PF00994.24 AIM20252.1 - 2.6e-27 95.3 0.0 3.3e-27 94.9 0.0 1.1 1 0 0 1 1 1 1 Probable molybdopterin binding domain Gpr1_Fun34_YaaH PF01184.19 AIM20253.1 - 3e-42 144.6 18.4 4e-42 144.2 18.4 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family HSP70 PF00012.20 AIM20254.1 - 8.3e-265 879.6 17.5 9.8e-265 879.4 17.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 AIM20254.1 - 4.9e-15 55.2 2.6 1.1e-12 47.5 0.6 2.7 2 1 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 AIM20254.1 - 0.00025 20.8 0.0 0.00051 19.8 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 AIM20254.1 - 0.33 11.4 7.6 3.1 8.3 0.4 3.6 3 2 0 3 3 3 0 Cell division protein FtsA DnaJ_C PF01556.18 AIM20255.1 - 1.6e-46 158.1 0.0 2.1e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 AIM20255.1 - 2.1e-27 95.0 5.7 3.7e-27 94.2 5.7 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 AIM20255.1 - 3e-16 59.5 16.1 5.2e-16 58.8 16.1 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 AIM20255.1 - 3.9e-07 29.9 13.6 3.9e-05 23.5 2.5 2.7 1 1 1 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein Cytochrome_C7 PF14522.6 AIM20255.1 - 0.0051 16.8 11.9 0.77 9.8 12.0 2.8 1 1 0 1 1 1 1 Cytochrome c7 and related cytochrome c LTXXQ PF07813.12 AIM20255.1 - 0.023 15.4 0.8 2.9 8.7 0.6 2.3 2 0 0 2 2 2 0 LTXXQ motif family protein DUF5351 PF17302.2 AIM20255.1 - 0.51 10.6 16.0 5.8 7.2 0.3 4.6 4 0 0 4 4 4 0 Family of unknown function (DUF5351) Cytochrom_c3_2 PF14537.6 AIM20255.1 - 0.68 10.4 14.3 9.8 6.7 8.7 3.2 1 1 1 2 2 2 0 Cytochrome c3 TackOD1 PF18551.1 AIM20255.1 - 1.1 8.9 6.7 0.83 9.3 1.6 2.3 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 zinc_ribbon_9 PF14369.6 AIM20255.1 - 1.1 9.6 10.3 11 6.4 0.2 3.4 3 0 0 3 3 3 0 zinc-ribbon RseC_MucC PF04246.12 AIM20255.1 - 1.3 9.0 4.1 0.32 10.9 0.9 1.6 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF1356 PF07092.12 AIM20255.1 - 5.6 6.2 8.6 1.4 8.1 2.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) zinc-ribbons_6 PF07191.12 AIM20255.1 - 6.1 6.9 7.9 15 5.6 7.9 1.7 1 0 0 1 1 1 0 zinc-ribbons Na_H_antiport_1 PF06965.12 AIM20256.1 - 1.3e-148 494.9 32.8 1.4e-148 494.7 32.8 1.0 1 0 0 1 1 1 1 Na+/H+ antiporter 1 GPI2 PF06432.11 AIM20256.1 - 0.32 10.4 5.1 0.84 9.0 5.1 1.7 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase HTH_1 PF00126.27 AIM20257.1 - 6e-16 58.1 0.0 1.2e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 AIM20257.1 - 4.8e-10 39.2 0.0 6.9e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_30 PF13556.6 AIM20257.1 - 0.096 12.5 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain R2K_2 PF18299.1 AIM20257.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 2 Ribosomal_S20p PF01649.18 AIM20258.1 - 1.3e-28 99.4 14.0 1.4e-28 99.3 14.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S20 TetR_C_24 PF17932.1 AIM20258.1 - 0.077 13.3 0.3 0.1 12.8 0.3 1.3 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain FAD_syn PF06574.12 AIM20259.1 - 3.1e-57 192.9 0.0 4.2e-57 192.5 0.0 1.2 1 0 0 1 1 1 1 FAD synthetase Flavokinase PF01687.17 AIM20259.1 - 1.7e-39 134.6 0.0 3.1e-39 133.7 0.0 1.4 1 0 0 1 1 1 1 Riboflavin kinase CTP_transf_like PF01467.26 AIM20259.1 - 1.7e-06 28.3 0.0 4.5e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 Cytidylyltransferase-like tRNA-synt_1 PF00133.22 AIM20260.1 - 1.3e-226 753.6 0.0 1.6e-226 753.3 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 AIM20260.1 - 2.5e-28 99.0 0.0 4.5e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 AIM20260.1 - 9.8e-19 67.3 0.0 4.3e-10 38.9 0.0 3.5 3 1 0 3 3 3 3 tRNA synthetases class I (M) zf-FPG_IleRS PF06827.14 AIM20260.1 - 1.7e-09 37.4 1.7 1.7e-09 37.4 1.7 2.2 2 0 0 2 2 2 1 Zinc finger found in FPG and IleRS tRNA-synt_1e PF01406.19 AIM20260.1 - 3.7e-07 29.8 0.0 9.3e-06 25.2 0.0 2.3 2 1 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 AIM20260.1 - 5.6e-06 25.5 0.0 2.4e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (K) tRNA-synt_1_2 PF13603.6 AIM20260.1 - 3.4e-05 23.5 0.0 5.8e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 Peptidase_A8 PF01252.18 AIM20261.1 - 2.7e-38 131.4 8.5 3.1e-38 131.2 8.5 1.0 1 0 0 1 1 1 1 Signal peptidase (SPase) II DUF4956 PF16316.5 AIM20261.1 - 0.092 12.4 0.4 0.15 11.7 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4956) ThrE PF06738.12 AIM20261.1 - 0.28 10.5 6.8 0.34 10.2 6.0 1.6 1 1 0 1 1 1 0 Putative threonine/serine exporter FKBP_C PF00254.28 AIM20262.1 - 1e-13 51.4 0.0 1.7e-13 50.7 0.0 1.5 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase LYTB PF02401.18 AIM20263.1 - 7.6e-92 307.3 0.0 8.6e-92 307.1 0.0 1.0 1 0 0 1 1 1 1 LytB protein ETF_alpha PF00766.19 AIM20263.1 - 0.0035 17.3 0.1 0.0084 16.1 0.1 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain LysR_substrate PF03466.20 AIM20264.1 - 5e-41 140.4 0.8 7e-41 139.9 0.8 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM20264.1 - 1.2e-20 73.2 1.8 3.2e-20 71.8 0.4 2.3 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_5 PF01022.20 AIM20264.1 - 0.0017 18.2 0.3 0.0071 16.2 0.1 2.2 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 AIM20264.1 - 0.0028 17.2 0.0 0.032 13.8 0.0 2.8 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 AIM20264.1 - 0.011 15.8 0.0 0.029 14.5 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_30 PF13556.6 AIM20264.1 - 0.018 14.8 0.0 0.15 11.9 0.0 2.4 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_20 PF12840.7 AIM20264.1 - 0.019 15.0 0.2 0.082 13.0 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain MarR_2 PF12802.7 AIM20264.1 - 0.039 13.8 0.1 0.25 11.3 0.0 2.3 2 0 0 2 2 2 0 MarR family HTH_11 PF08279.12 AIM20264.1 - 0.11 12.4 0.0 0.35 10.9 0.0 1.9 1 0 0 1 1 1 0 HTH domain DIT1_PvcA PF05141.12 AIM20265.1 - 2.5e-80 269.9 0.0 3e-80 269.6 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein DUF5644 PF18712.1 AIM20265.1 - 0.085 12.9 0.0 0.3 11.1 0.0 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5644) Glyco_transf_28 PF03033.20 AIM20266.1 - 1e-08 35.3 0.0 2e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 AIM20266.1 - 4.4e-08 32.4 0.0 1.1e-07 31.1 0.0 1.5 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_4_4 PF13579.6 AIM20266.1 - 0.00083 19.8 2.7 0.00083 19.8 2.7 3.0 2 1 0 3 3 3 1 Glycosyl transferase 4-like domain Glyco_tran_28_C PF04101.16 AIM20266.1 - 0.0033 17.4 0.0 0.0049 16.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_4 PF13439.6 AIM20266.1 - 0.0099 15.9 2.1 0.024 14.6 0.3 2.4 2 1 0 2 2 2 1 Glycosyltransferase Family 4 IMP2_C PF18591.1 AIM20266.1 - 0.055 13.3 0.2 0.24 11.3 0.1 2.0 2 0 0 2 2 2 0 Immune Mapped Protein 2 (IMP2) C-terminal domain DapB_C PF05173.14 AIM20267.1 - 5.7e-43 145.8 0.1 8.4e-43 145.3 0.1 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, C-terminus DapB_N PF01113.20 AIM20267.1 - 6.8e-43 145.7 0.9 2.2e-42 144.1 0.1 2.1 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus CPSase_sm_chain PF00988.22 AIM20268.1 - 2.9e-53 179.1 0.0 4.9e-53 178.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 AIM20268.1 - 7.7e-50 169.3 0.0 1.3e-49 168.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AIM20268.1 - 8.2e-08 32.3 0.3 5.1e-06 26.4 0.3 2.3 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 AIM20268.1 - 0.0013 18.5 0.0 0.003 17.4 0.0 1.6 1 0 0 1 1 1 1 DJ-1/PfpI family Nif11 PF07862.11 AIM20268.1 - 0.16 12.3 0.0 7.5 6.9 0.0 2.9 3 0 0 3 3 3 0 Nif11 domain CPSase_L_D2 PF02786.17 AIM20269.1 - 7.9e-117 388.2 1.4 1.1e-76 257.0 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 AIM20269.1 - 2.9e-40 137.4 0.0 7.1e-40 136.1 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain MGS PF02142.22 AIM20269.1 - 1.5e-18 66.8 0.0 1.2e-17 63.8 0.0 2.6 2 0 0 2 2 2 1 MGS-like domain ATP-grasp PF02222.22 AIM20269.1 - 2e-14 53.5 0.1 7.6e-07 28.8 0.1 2.3 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.14 AIM20269.1 - 4.6e-12 46.3 0.2 1.1e-08 35.2 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 AIM20269.1 - 1.8e-11 43.9 0.0 4.6e-07 29.6 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.13 AIM20269.1 - 9.8e-10 38.3 0.1 6.6e-05 22.5 0.0 2.3 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp_4 PF13535.6 AIM20269.1 - 1.8e-09 37.4 0.0 8.2e-05 22.3 0.0 4.2 3 2 0 3 3 3 2 ATP-grasp domain CoA_binding_2 PF13380.6 AIM20269.1 - 0.004 17.6 0.0 3.9 8.0 0.0 3.7 3 1 0 3 3 3 1 CoA binding domain ATP-grasp_5 PF13549.6 AIM20269.1 - 0.0047 16.4 0.0 4.7 6.6 0.0 3.3 3 0 0 3 3 3 1 ATP-grasp domain SmpA_OmlA PF04355.13 AIM20269.1 - 0.027 14.2 0.0 0.059 13.2 0.0 1.5 1 0 0 1 1 1 0 SmpA / OmlA family Flavodoxin_2 PF02525.17 AIM20270.1 - 1.6e-39 135.7 0.0 1.8e-39 135.5 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 AIM20270.1 - 5.7e-06 26.2 0.1 1e-05 25.3 0.0 1.6 2 0 0 2 2 2 1 NADPH-dependent FMN reductase Na_H_Exchanger PF00999.21 AIM20271.1 - 3.6e-63 213.6 52.8 4.6e-63 213.3 52.8 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TrkA_N PF02254.18 AIM20271.1 - 8e-26 90.6 0.1 7.7e-25 87.4 0.0 2.2 2 0 0 2 2 2 1 TrkA-N domain Sulfotransfer_4 PF17784.1 AIM20271.1 - 0.0026 17.6 0.0 0.0038 17.1 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sacchrp_dh_NADP PF03435.18 AIM20271.1 - 0.072 13.4 0.1 0.16 12.2 0.1 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain IFT57 PF10498.9 AIM20271.1 - 0.09 11.7 0.3 0.13 11.2 0.3 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 ApbA PF02558.16 AIM20271.1 - 0.098 12.3 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 AIM20271.1 - 0.1 13.1 0.1 0.24 11.9 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 AIM20271.1 - 0.16 11.2 0.1 0.31 10.2 0.0 1.3 1 1 0 1 1 1 0 FAD binding domain LysE PF01810.18 AIM20272.1 - 2e-35 122.0 10.8 2.3e-35 121.8 10.8 1.0 1 0 0 1 1 1 1 LysE type translocator TerC PF03741.16 AIM20272.1 - 0.00097 18.9 3.1 0.0018 18.0 3.0 1.7 1 1 0 1 1 1 1 Integral membrane protein TerC family DUF2530 PF10745.9 AIM20272.1 - 0.79 10.0 5.5 3 8.2 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2530) ThrE PF06738.12 AIM20273.1 - 4.4e-65 219.4 11.8 5e-65 219.2 11.8 1.0 1 0 0 1 1 1 1 Putative threonine/serine exporter ThrE_2 PF12821.7 AIM20273.1 - 0.00076 19.6 12.9 0.0013 18.8 12.9 1.4 1 0 0 1 1 1 1 Threonine/Serine exporter, ThrE SpoIIIAC PF06686.11 AIM20273.1 - 0.031 14.4 1.6 10 6.4 0.2 2.8 2 0 0 2 2 2 0 Stage III sporulation protein AC/AD protein family ThrE_2 PF12821.7 AIM20274.1 - 9.3e-36 122.8 13.0 1.1e-35 122.6 13.0 1.0 1 0 0 1 1 1 1 Threonine/Serine exporter, ThrE ThrE PF06738.12 AIM20274.1 - 0.00046 19.6 14.3 0.00056 19.3 14.3 1.2 1 0 0 1 1 1 1 Putative threonine/serine exporter DHFR_1 PF00186.19 AIM20275.1 - 1.6e-59 200.2 0.0 1.8e-59 200.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrofolate reductase DUF839 PF05787.13 AIM20276.1 - 3.9e-188 626.9 3.5 4.4e-188 626.7 3.5 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF839) TAT_signal PF10518.9 AIM20276.1 - 0.17 11.8 0.8 0.34 10.8 0.8 1.5 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Metallophos PF00149.28 AIM20277.1 - 2.1e-14 54.5 0.0 1.3e-13 52.0 0.0 2.1 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AIM20277.1 - 8.7e-06 26.0 0.0 1.3e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain FBPase_2 PF06874.11 AIM20277.1 - 0.17 10.2 0.0 0.25 9.6 0.0 1.3 1 1 0 1 1 1 0 Firmicute fructose-1,6-bisphosphatase DUF525 PF04379.14 AIM20278.1 - 3.1e-34 117.1 0.1 3.7e-34 116.8 0.1 1.1 1 0 0 1 1 1 1 ApaG domain DUF4354 PF14263.6 AIM20278.1 - 0.07 12.9 0.0 0.088 12.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4354) RrnaAD PF00398.20 AIM20279.1 - 3.1e-80 269.1 0.0 3.5e-80 268.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase NodS PF05401.11 AIM20279.1 - 0.06 12.9 0.0 0.71 9.5 0.0 2.2 2 0 0 2 2 2 0 Nodulation protein S (NodS) PdxA PF04166.12 AIM20280.1 - 1.2e-107 359.5 0.0 1.5e-107 359.2 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthetic protein PdxA Rotamase_3 PF13616.6 AIM20281.1 - 3.6e-47 159.7 0.0 1.1e-24 87.3 0.0 2.4 2 0 0 2 2 2 2 PPIC-type PPIASE domain Rotamase PF00639.21 AIM20281.1 - 1e-46 157.8 0.0 2.8e-23 82.7 0.0 2.8 2 0 0 2 2 2 2 PPIC-type PPIASE domain SurA_N PF09312.11 AIM20281.1 - 3.7e-45 152.8 6.8 9.9e-45 151.4 6.8 1.8 1 0 0 1 1 1 1 SurA N-terminal domain Rotamase_2 PF13145.6 AIM20281.1 - 2.2e-16 60.8 1.2 7.6e-08 33.2 0.1 3.6 2 1 1 3 3 3 2 PPIC-type PPIASE domain SurA_N_3 PF13624.6 AIM20281.1 - 9.2e-16 58.0 2.5 2e-15 56.9 2.5 1.6 1 0 0 1 1 1 1 SurA N-terminal domain SurA_N_2 PF13623.6 AIM20281.1 - 3.8e-08 33.3 3.7 5.7e-08 32.8 2.1 2.1 1 1 0 1 1 1 1 SurA N-terminal domain Trigger_C PF05698.14 AIM20281.1 - 0.00033 20.7 1.9 0.0009 19.3 1.5 2.1 1 1 0 1 1 1 1 Bacterial trigger factor protein (TF) C-terminus 2-Hacid_dh PF00389.30 AIM20281.1 - 0.065 12.9 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Cas6b_C PF17262.2 AIM20281.1 - 0.19 11.8 1.1 1.5 9.0 0.3 2.6 2 1 1 3 3 3 0 Cas6b C-terminal domain LptD PF04453.14 AIM20282.1 - 1.7e-107 360.0 26.8 1.7e-107 360.0 26.8 1.8 2 0 0 2 2 2 1 LPS transport system D OstA PF03968.14 AIM20282.1 - 9.8e-28 96.6 0.3 2.6e-27 95.3 0.3 1.8 1 0 0 1 1 1 1 OstA-like protein TerB PF05099.13 AIM20283.1 - 5.8e-13 49.0 0.8 5.8e-13 49.0 0.8 1.5 2 0 0 2 2 2 1 Tellurite resistance protein TerB DnaJ PF00226.31 AIM20283.1 - 2.8e-10 40.2 0.1 5.6e-10 39.2 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain HTH_10 PF04967.12 AIM20283.1 - 0.0022 17.7 0.0 0.41 10.5 0.0 2.6 2 0 0 2 2 2 1 HTH DNA binding domain DUF4311 PF14188.6 AIM20283.1 - 0.051 13.3 0.1 0.071 12.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4311) Acetyltransf_11 PF13720.6 AIM20283.1 - 0.14 12.7 2.4 11 6.6 0.2 3.0 2 1 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 PrsW-protease PF13367.6 AIM20283.1 - 0.8 9.1 2.5 3.7 6.9 2.5 1.9 1 1 0 1 1 1 0 PrsW family intramembrane metalloprotease PseudoU_synth_2 PF00849.22 AIM20284.1 - 3.3e-27 95.5 0.0 4.2e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 RNA pseudouridylate synthase RapA_C PF12137.8 AIM20285.1 - 1.1e-156 521.4 1.2 1.9e-156 520.7 1.2 1.4 1 0 0 1 1 1 1 RNA polymerase recycling family C-terminal Tudor_RapA PF18337.1 AIM20285.1 - 1.1e-27 96.0 0.0 2.9e-27 94.6 0.0 1.8 1 0 0 1 1 1 1 RapA N-terminal Tudor like domain Tudor_1_RapA PF18339.1 AIM20285.1 - 4.5e-24 84.1 0.0 1e-23 83.0 0.0 1.7 1 0 0 1 1 1 1 RapA N-terminal Tudor like domain 1 SNF2_N PF00176.23 AIM20285.1 - 1.8e-18 66.4 0.0 3.9e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 AIM20285.1 - 3.6e-16 59.5 0.0 1e-15 58.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 AIM20285.1 - 3.1e-12 46.8 0.0 1e-11 45.1 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 AIM20285.1 - 1.9e-06 27.8 0.1 6.7e-06 26.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_34 PF13872.6 AIM20285.1 - 0.0081 15.1 0.0 0.046 12.6 0.0 2.1 1 1 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 AAA_22 PF13401.6 AIM20285.1 - 0.024 14.9 0.8 0.5 10.6 0.1 3.4 3 1 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 AIM20285.1 - 0.063 13.0 0.0 2.6 7.8 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein COG2 PF06148.11 AIM20285.1 - 0.21 11.7 5.3 0.12 12.5 2.3 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DNA_pol_B PF00136.21 AIM20286.1 - 4.5e-43 147.6 0.0 4e-42 144.5 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 AIM20286.1 - 6.7e-12 45.2 0.0 3.1e-09 36.5 0.0 2.7 1 1 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B_2 PF03175.13 AIM20286.1 - 7.4e-06 25.1 0.0 0.00062 18.7 0.0 2.1 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral GGDEF_2 PF17853.1 AIM20286.1 - 0.011 16.0 0.1 0.61 10.4 0.0 2.8 2 0 0 2 2 2 0 GGDEF-like domain P63C PF10546.9 AIM20286.1 - 0.038 14.6 0.8 0.094 13.3 0.8 1.6 1 0 0 1 1 1 0 P63C domain RNase_H_2 PF13482.6 AIM20286.1 - 0.091 12.7 0.0 1.6 8.7 0.0 2.9 2 1 0 2 2 2 0 RNase_H superfamily SNARE_assoc PF09335.11 AIM20287.1 - 1.5e-18 67.4 1.5 1.5e-18 67.4 1.5 2.2 1 1 1 2 2 2 1 SNARE associated Golgi protein ACT_5 PF13710.6 AIM20288.1 - 7.1e-10 38.6 0.0 1.1e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 ACT domain ACT PF01842.25 AIM20288.1 - 1.3e-09 37.7 0.0 2.1e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 AIM20288.1 - 0.00013 22.5 0.0 0.00017 22.1 0.0 1.2 1 0 0 1 1 1 1 ACT domain Ribosomal_L1 PF00687.21 AIM20288.1 - 0.16 11.7 0.0 0.19 11.4 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L1p/L10e family TPP_enzyme_N PF02776.18 AIM20289.1 - 2.2e-58 196.6 0.6 5.8e-58 195.3 0.2 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 AIM20289.1 - 2.6e-50 170.2 0.6 6e-50 169.0 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 AIM20289.1 - 1.1e-45 154.7 0.6 2.3e-45 153.7 0.6 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_M_2 PF16582.5 AIM20289.1 - 0.095 12.4 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Middle domain of thiamine pyrophosphate CO_dh PF02552.16 AIM20289.1 - 0.15 11.8 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit ABC_tran PF00005.27 AIM20290.1 - 6.8e-35 120.6 0.0 9.8e-35 120.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIM20290.1 - 5.8e-12 46.0 2.9 1.8e-08 34.6 0.1 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIM20290.1 - 2e-05 24.1 0.1 0.00023 20.7 0.1 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AIM20290.1 - 0.00013 22.4 1.8 0.00027 21.4 1.8 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AIM20290.1 - 0.001 18.8 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AIM20290.1 - 0.001 19.3 2.1 0.024 14.9 2.0 2.3 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 AIM20290.1 - 0.0012 19.1 0.4 0.027 14.7 0.4 2.4 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 AIM20290.1 - 0.003 17.2 0.0 0.035 13.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 AIM20290.1 - 0.0094 15.9 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 AIM20290.1 - 0.011 15.5 0.2 0.16 11.7 0.0 2.4 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 AIM20290.1 - 0.032 13.4 0.0 7.8 5.6 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain MMR_HSR1 PF01926.23 AIM20290.1 - 0.039 14.0 0.0 0.1 12.7 0.0 1.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.12 AIM20290.1 - 0.05 13.5 1.0 0.73 9.7 0.0 2.4 2 1 0 2 2 2 0 NACHT domain DUF87 PF01935.17 AIM20290.1 - 0.055 13.6 0.0 0.091 12.8 0.0 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_33 PF13671.6 AIM20290.1 - 0.086 13.0 0.2 0.3 11.2 0.2 2.0 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 AIM20290.1 - 0.14 11.9 0.1 2.3 7.9 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.6 AIM20290.1 - 0.23 11.2 0.0 0.44 10.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 AIM20290.1 - 0.26 11.5 1.2 0.55 10.5 0.8 2.0 1 1 0 1 1 1 0 AAA domain BPD_transp_1 PF00528.22 AIM20291.1 - 3.6e-20 72.5 28.8 1e-13 51.4 6.9 3.5 1 1 2 3 3 3 3 Binding-protein-dependent transport system inner membrane component SBP_bac_6 PF13343.6 AIM20292.1 - 6.6e-19 68.3 0.9 8.5e-19 67.9 0.9 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AIM20292.1 - 2.2e-15 57.5 6.1 2.9e-15 57.0 6.1 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 AIM20292.1 - 7.1e-15 55.4 0.3 8.7e-15 55.1 0.3 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SgrT PF15894.5 AIM20293.1 - 3.9e-18 65.2 1.5 4.7e-18 64.9 1.5 1.0 1 0 0 1 1 1 1 Inhibitor of glucose uptake transporter SgrT MFS_1 PF07690.16 AIM20294.1 - 5e-38 130.9 49.5 1.4e-34 119.6 36.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 AIM20294.1 - 5.3e-10 38.4 32.5 1.3e-09 37.2 22.5 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein Nuc_H_symport PF03825.16 AIM20294.1 - 3.7e-09 36.1 23.3 5.2e-09 35.6 23.3 1.2 1 0 0 1 1 1 1 Nucleoside H+ symporter MFS_1_like PF12832.7 AIM20294.1 - 4.1e-09 35.8 19.1 2.7e-08 33.1 6.0 2.5 1 1 0 2 2 2 2 MFS_1 like family Na_sulph_symp PF00939.19 AIM20295.1 - 2e-136 455.8 40.2 2.3e-136 455.6 40.2 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 AIM20295.1 - 7e-17 61.6 50.7 3.8e-16 59.2 41.5 2.4 1 1 1 2 2 2 2 Citrate transporter Aconitase_C PF00694.19 AIM20296.1 - 2e-41 141.4 0.0 2.7e-41 141.0 0.0 1.2 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase PF00330.20 AIM20297.1 - 1.3e-164 548.6 1.3 1.5e-164 548.4 1.3 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Spo0M PF07070.11 AIM20297.1 - 0.044 13.3 0.6 0.073 12.6 0.6 1.3 1 0 0 1 1 1 0 SpoOM protein Iso_dh PF00180.20 AIM20298.1 - 7.3e-137 456.2 0.0 8.2e-137 456.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HMGL-like PF00682.19 AIM20299.1 - 4.6e-107 357.5 4.1 6.8e-107 356.9 4.1 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 AIM20299.1 - 3.3e-37 127.3 0.1 8.7e-37 126.0 0.1 1.8 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain NAD_binding_10 PF13460.6 AIM20299.1 - 0.066 13.1 0.4 2 8.3 0.1 2.4 2 0 0 2 2 2 0 NAD(P)H-binding HTH_1 PF00126.27 AIM20300.1 - 2e-17 62.9 0.0 3.3e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 AIM20300.1 - 4.7e-17 62.1 0.0 6.6e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 LysR substrate binding domain DUF3089 PF11288.8 AIM20300.1 - 0.11 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) AMP-binding PF00501.28 AIM20301.1 - 8.8e-94 314.5 0.0 1.1e-93 314.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme TPP_enzyme_N PF02776.18 AIM20302.1 - 8.4e-61 204.5 0.5 1.9e-58 196.9 0.1 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 AIM20302.1 - 2.6e-53 179.9 0.0 1.6e-51 174.1 0.0 2.7 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 AIM20302.1 - 3.1e-48 163.0 0.3 7.8e-48 161.7 0.1 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 AIM20302.1 - 0.0048 16.7 1.0 0.019 14.7 1.1 1.9 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg ALS_ss_C PF10369.9 AIM20303.1 - 6.2e-25 87.2 0.9 1.1e-23 83.2 0.3 2.1 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 AIM20303.1 - 1.5e-15 56.6 0.0 3.3e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 AIM20303.1 - 5.4e-15 55.0 0.1 1.1e-14 54.0 0.1 1.6 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 AIM20303.1 - 1.2e-05 25.8 0.3 8.4e-05 23.1 0.1 2.1 2 0 0 2 2 2 1 ACT domain MeaB PF03308.16 AIM20303.1 - 0.049 12.6 1.7 0.067 12.2 1.7 1.3 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB LacI PF00356.21 AIM20304.1 - 2.6e-19 68.7 0.8 5.3e-19 67.7 0.8 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_1 PF00532.21 AIM20304.1 - 4.7e-16 59.0 0.0 6e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_3 PF13377.6 AIM20304.1 - 5.8e-13 49.5 0.2 3.7e-11 43.6 0.0 2.3 1 1 1 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_4 PF13407.6 AIM20304.1 - 2.6e-09 37.0 0.0 3.5e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain HTH_3 PF01381.22 AIM20304.1 - 0.017 15.1 0.0 0.046 13.8 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix AlaE PF06610.13 AIM20305.1 - 8.8e-68 226.8 3.0 9.9e-68 226.6 3.0 1.0 1 0 0 1 1 1 1 L-alanine exporter MraZ PF02381.18 AIM20306.1 - 2.1e-47 158.9 0.2 8.5e-24 83.3 0.0 2.0 2 0 0 2 2 2 2 MraZ protein, putative antitoxin-like Methyltransf_5 PF01795.19 AIM20307.1 - 3.9e-117 391.2 0.0 4.3e-117 391.0 0.0 1.0 1 0 0 1 1 1 1 MraW methylase family Methyltransf_31 PF13847.6 AIM20307.1 - 0.0012 18.7 0.0 0.093 12.5 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 AIM20307.1 - 0.0084 16.8 0.0 0.35 11.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_24 PF13578.6 AIM20307.1 - 0.018 16.1 0.0 0.12 13.4 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain FtsJ PF01728.19 AIM20307.1 - 0.16 12.1 0.0 0.64 10.1 0.0 1.8 1 1 0 1 1 1 0 FtsJ-like methyltransferase FtsL PF04999.13 AIM20308.1 - 5.2e-33 112.9 0.8 5.8e-33 112.8 0.8 1.0 1 0 0 1 1 1 1 Cell division protein FtsL DivIC PF04977.15 AIM20308.1 - 0.0057 16.4 0.3 0.0075 16.0 0.3 1.1 1 0 0 1 1 1 1 Septum formation initiator Transpeptidase PF00905.22 AIM20309.1 - 3.1e-83 279.5 0.1 3.8e-83 279.2 0.1 1.1 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain PBP_dimer PF03717.15 AIM20309.1 - 1.5e-19 71.1 0.0 3.1e-18 66.8 0.0 2.2 1 1 0 1 1 1 1 Penicillin-binding Protein dimerisation domain Mur_ligase_M PF08245.12 AIM20310.1 - 8.3e-52 176.0 0.1 1.3e-51 175.3 0.1 1.3 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 AIM20310.1 - 1.6e-26 92.4 0.0 1.6e-25 89.2 0.0 2.4 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain Mur_ligase PF01225.25 AIM20310.1 - 8.1e-13 48.5 3.2 2.9e-12 46.7 0.4 2.9 3 0 0 3 3 3 1 Mur ligase family, catalytic domain GGDEF_2 PF17853.1 AIM20310.1 - 0.13 12.5 1.2 0.85 9.9 0.1 2.8 2 2 1 3 3 3 0 GGDEF-like domain SRP54 PF00448.22 AIM20310.1 - 0.53 9.9 2.3 1.8 8.2 0.4 2.5 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain Mur_ligase_M PF08245.12 AIM20311.1 - 1e-47 162.6 0.0 1.7e-47 161.9 0.0 1.4 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 AIM20311.1 - 3.9e-17 62.3 0.1 6.5e-15 55.2 0.0 2.8 1 1 1 2 2 2 2 Mur ligase family, glutamate ligase domain Mur_ligase PF01225.25 AIM20311.1 - 7.2e-11 42.3 1.0 1.7e-09 37.9 0.0 2.8 2 0 0 2 2 2 1 Mur ligase family, catalytic domain Glycos_transf_4 PF00953.21 AIM20312.1 - 6e-37 127.1 15.3 6e-37 127.1 15.3 2.1 3 0 0 3 3 3 1 Glycosyl transferase family 4 MraY_sig1 PF10555.9 AIM20312.1 - 1e-05 24.8 3.3 1e-05 24.8 3.3 2.7 2 0 0 2 2 2 1 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 Ndc1_Nup PF09531.10 AIM20312.1 - 0.0014 17.4 0.6 0.0014 17.4 0.6 1.7 3 0 0 3 3 3 1 Nucleoporin protein Ndc1-Nup Mur_ligase_M PF08245.12 AIM20313.1 - 1.1e-27 97.2 0.0 2.1e-27 96.4 0.0 1.4 2 0 0 2 2 2 1 Mur ligase middle domain Mur_ligase_C PF02875.21 AIM20313.1 - 9.8e-09 35.4 0.0 4.8e-08 33.1 0.0 2.2 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain NAD_binding_7 PF13241.6 AIM20313.1 - 0.11 12.9 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding FTSW_RODA_SPOVE PF01098.19 AIM20314.1 - 2e-124 415.2 23.9 2.4e-124 415.0 23.9 1.0 1 0 0 1 1 1 1 Cell cycle protein DUF1422 PF07226.11 AIM20314.1 - 1.5 8.9 9.1 0.29 11.1 3.8 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1422) DUF2542 PF10808.8 AIM20314.1 - 6.1 7.4 8.5 15 6.1 0.2 4.4 3 1 1 4 4 4 0 Protein of unknown function (DUF2542) Glyco_transf_28 PF03033.20 AIM20315.1 - 5e-49 165.9 0.1 9.1e-49 165.1 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_tran_28_C PF04101.16 AIM20315.1 - 3.9e-37 127.8 0.0 5.5e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_4 PF13439.6 AIM20315.1 - 3e-08 33.9 0.3 1.4e-07 31.6 0.1 2.0 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 AIM20315.1 - 1.4e-07 32.0 0.5 4.7e-06 27.1 0.1 2.6 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 AIM20315.1 - 3.5e-06 27.6 1.5 3.5e-06 27.6 1.5 2.4 1 1 0 2 2 2 1 Glycosyl transferase 4-like domain Mur_ligase PF01225.25 AIM20316.1 - 3.5e-30 104.2 0.2 9.2e-30 102.8 0.2 1.8 1 0 0 1 1 1 1 Mur ligase family, catalytic domain Mur_ligase_M PF08245.12 AIM20316.1 - 1.1e-26 94.1 0.0 1.5e-26 93.6 0.0 1.2 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 AIM20316.1 - 4.2e-22 78.2 0.0 2.2e-21 75.9 0.0 2.3 3 0 0 3 3 3 1 Mur ligase family, glutamate ligase domain Dala_Dala_lig_C PF07478.13 AIM20317.1 - 3.6e-66 222.6 0.0 4.4e-66 222.3 0.0 1.1 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Dala_Dala_lig_N PF01820.21 AIM20317.1 - 4e-18 65.8 0.5 2.4e-16 60.1 0.5 2.4 1 1 0 1 1 1 1 D-ala D-ala ligase N-terminus CPSase_L_D2 PF02786.17 AIM20317.1 - 4.2e-10 39.5 0.0 6e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.6 AIM20317.1 - 8.8e-07 28.6 0.0 8.7e-06 25.4 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 AIM20317.1 - 0.00015 21.9 0.0 0.00034 20.7 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 AIM20317.1 - 0.00023 20.8 0.0 0.00047 19.8 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.6 AIM20317.1 - 0.002 17.9 0.0 0.018 14.8 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon RimK PF08443.11 AIM20317.1 - 0.0089 15.6 0.0 0.05 13.2 0.0 1.9 1 1 0 1 1 1 1 RimK-like ATP-grasp domain TTL PF03133.15 AIM20317.1 - 0.014 14.5 0.0 0.032 13.3 0.0 1.5 2 0 0 2 2 2 0 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 AIM20317.1 - 0.021 14.1 0.0 0.29 10.4 0.0 2.1 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 AIM20317.1 - 0.17 11.1 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 YheC/D like ATP-grasp FtsQ PF03799.15 AIM20318.1 - 1.2e-26 93.8 0.2 2.1e-26 93.1 0.2 1.4 1 0 0 1 1 1 1 Cell division protein FtsQ POTRA_1 PF08478.10 AIM20318.1 - 2.8e-22 78.8 0.1 5.8e-22 77.8 0.1 1.5 1 0 0 1 1 1 1 POTRA domain, FtsQ-type FtsA PF14450.6 AIM20319.1 - 1.8e-33 115.1 1.0 6.8e-24 84.3 0.0 2.1 2 0 0 2 2 2 2 Cell division protein FtsA SHS2_FTSA PF02491.20 AIM20319.1 - 2.6e-30 104.6 2.2 5.6e-30 103.6 2.2 1.6 1 0 0 1 1 1 1 SHS2 domain inserted in FTSA PilM_2 PF11104.8 AIM20319.1 - 1.3e-10 40.8 0.5 2.8e-07 29.9 0.1 2.7 2 1 0 2 2 2 2 Type IV pilus assembly protein PilM; MreB_Mbl PF06723.13 AIM20319.1 - 5.2e-10 38.7 0.4 5.2e-10 38.7 0.4 1.8 2 1 1 3 3 3 1 MreB/Mbl protein DDR PF08841.10 AIM20319.1 - 0.00058 18.9 1.2 0.0017 17.5 1.1 1.8 1 1 1 2 2 2 1 Diol dehydratase reactivase ATPase-like domain EutA PF06277.11 AIM20319.1 - 0.001 18.0 0.2 0.0022 16.9 0.1 1.8 2 0 0 2 2 2 1 Ethanolamine utilisation protein EutA Hydantoinase_A PF01968.18 AIM20319.1 - 0.033 13.5 0.5 0.077 12.2 0.1 1.8 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase Actin PF00022.19 AIM20319.1 - 0.033 12.8 0.7 5 5.6 0.1 2.5 2 1 0 3 3 3 0 Actin HSP70 PF00012.20 AIM20319.1 - 0.047 11.9 0.5 0.19 9.9 0.2 2.0 2 0 0 2 2 2 0 Hsp70 protein SrfB PF07520.11 AIM20319.1 - 0.29 9.0 0.4 0.45 8.3 0.1 1.4 2 0 0 2 2 2 0 Virulence factor SrfB Tubulin PF00091.25 AIM20320.1 - 1.5e-41 142.8 0.6 2.1e-41 142.3 0.6 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.8 AIM20320.1 - 2.1e-37 127.3 1.0 6.1e-37 125.8 1.0 1.8 1 0 0 1 1 1 1 FtsZ family, C-terminal domain NAD_binding_10 PF13460.6 AIM20320.1 - 0.0053 16.7 0.1 0.014 15.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)H-binding HATPase_c PF02518.26 AIM20320.1 - 0.098 13.2 0.2 0.29 11.7 0.0 1.8 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Tubulin_2 PF13809.6 AIM20320.1 - 0.11 11.7 7.2 1.7 7.7 1.9 2.3 1 1 1 2 2 2 0 Tubulin like LpxC PF03331.13 AIM20321.1 - 1.8e-108 362.1 0.0 2.1e-108 361.9 0.0 1.0 1 0 0 1 1 1 1 UDP-3-O-acyl N-acetylglycosamine deacetylase DciA PF05258.12 AIM20322.1 - 7.3e-16 58.4 0.3 1.3e-14 54.4 0.1 2.1 2 0 0 2 2 2 1 Dna[CI] antecedent, DciA PDE4_UCR PF18100.1 AIM20322.1 - 0.095 13.3 0.0 0.15 12.7 0.0 1.2 1 0 0 1 1 1 0 Phosphodiesterase 4 upstream conserved regions (UCR) SecM PF06558.12 AIM20323.1 - 6.1e-55 185.3 3.2 7.2e-55 185.1 3.2 1.1 1 0 0 1 1 1 1 Secretion monitor precursor protein (SecM) ABATE PF07336.11 AIM20323.1 - 0.082 13.6 4.4 0.15 12.7 4.2 1.7 1 1 0 1 1 1 0 Putative stress-induced transcription regulator DUF2547 PF10818.8 AIM20323.1 - 0.093 13.7 1.5 0.78 10.7 0.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2547) SecA_DEAD PF07517.14 AIM20324.1 - 2.1e-132 440.8 0.2 3.8e-132 440.0 0.2 1.4 1 0 0 1 1 1 1 SecA DEAD-like domain SecA_SW PF07516.13 AIM20324.1 - 1.6e-69 234.0 9.0 1.6e-69 234.0 9.0 2.0 3 0 0 3 3 3 1 SecA Wing and Scaffold domain SecA_PP_bind PF01043.20 AIM20324.1 - 1.1e-39 135.6 0.3 2.8e-39 134.2 0.3 1.8 1 0 0 1 1 1 1 SecA preprotein cross-linking domain SEC-C PF02810.15 AIM20324.1 - 6.8e-11 41.9 9.7 1.2e-10 41.1 9.7 1.4 1 0 0 1 1 1 1 SEC-C motif DEAD PF00270.29 AIM20324.1 - 0.0012 18.7 0.1 0.0092 15.8 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase DUF2175 PF09943.9 AIM20324.1 - 0.049 13.9 2.9 0.11 12.7 0.2 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) RPW8 PF05659.11 AIM20324.1 - 0.48 10.1 5.3 1.5 8.5 0.4 2.8 3 0 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 NUDIX PF00293.28 AIM20325.1 - 5.3e-22 78.3 1.6 5.9e-22 78.1 1.6 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 AIM20325.1 - 3.6e-21 75.2 0.2 4.1e-21 75.0 0.2 1.0 1 0 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.6 AIM20325.1 - 0.037 13.6 0.0 0.046 13.3 0.0 1.1 1 0 0 1 1 1 0 Nucleotide hydrolase YacG PF03884.14 AIM20326.1 - 3.3e-25 87.6 1.3 3.8e-25 87.4 1.3 1.1 1 0 0 1 1 1 1 DNA gyrase inhibitor YacG zf-HIT PF04438.16 AIM20326.1 - 0.037 13.9 1.6 0.069 13.0 1.6 1.4 1 1 0 1 1 1 0 HIT zinc finger ZapD PF07072.11 AIM20327.1 - 5e-77 258.4 1.7 5.8e-77 258.2 1.7 1.0 1 0 0 1 1 1 1 Cell division protein CoaE PF01121.20 AIM20328.1 - 8e-73 243.9 0.2 9.3e-73 243.7 0.2 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_33 PF13671.6 AIM20328.1 - 1e-05 25.7 0.4 5.6e-05 23.3 0.4 2.1 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 AIM20328.1 - 3.5e-05 24.1 1.6 0.00018 21.8 1.4 2.3 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 AIM20328.1 - 0.00025 21.6 0.0 0.0011 19.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 AIM20328.1 - 0.00027 21.1 0.0 0.00037 20.7 0.0 1.2 1 0 0 1 1 1 1 Cytidylate kinase-like family CbiA PF01656.23 AIM20328.1 - 0.01 15.9 1.0 2.1 8.4 0.1 2.3 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 AIM20328.1 - 0.01 16.1 0.2 0.037 14.3 0.2 2.1 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 AIM20328.1 - 0.017 15.5 3.8 0.083 13.3 3.8 2.0 1 1 0 1 1 1 0 AAA ATPase domain PRK PF00485.18 AIM20328.1 - 0.022 14.5 2.7 0.85 9.3 0.2 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_19 PF13245.6 AIM20328.1 - 0.023 15.0 0.2 0.03 14.7 0.2 1.4 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 AIM20328.1 - 0.025 13.9 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 KaiC SKI PF01202.22 AIM20328.1 - 0.026 14.6 0.1 2 8.5 0.0 2.3 2 0 0 2 2 2 0 Shikimate kinase TsaE PF02367.17 AIM20328.1 - 0.045 13.8 0.1 0.081 12.9 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 AIM20328.1 - 0.068 13.6 0.5 0.59 10.6 0.5 2.2 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AIM20328.1 - 0.098 12.4 0.0 0.39 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 AIM20328.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_29 PF13555.6 AIM20328.1 - 0.12 12.1 0.1 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Thymidylate_kin PF02223.17 AIM20328.1 - 0.12 12.0 0.4 17 5.0 0.1 2.7 2 1 0 3 3 3 0 Thymidylate kinase Sigma54_activ_2 PF14532.6 AIM20328.1 - 0.15 12.2 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 AIM20328.1 - 0.15 12.5 0.6 0.24 11.9 0.6 1.7 1 1 0 1 1 1 0 ABC transporter dNK PF01712.19 AIM20328.1 - 0.21 11.4 0.0 0.45 10.3 0.0 1.5 2 0 0 2 2 2 0 Deoxynucleoside kinase IMPDH PF00478.25 AIM20329.1 - 2.2e-78 263.7 0.8 2.9e-78 263.3 0.8 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 AIM20329.1 - 0.0037 16.3 4.7 0.0052 15.9 1.7 2.1 2 0 0 2 2 2 1 FMN-dependent dehydrogenase T2SSF PF00482.23 AIM20330.1 - 2.4e-58 195.5 8.8 4e-31 107.6 1.5 2.3 2 0 0 2 2 2 2 Type II secretion system (T2SS), protein F DUF948 PF06103.11 AIM20330.1 - 0.5 10.6 2.6 1.8 8.9 0.4 2.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) T2SSE PF00437.20 AIM20331.1 - 4.7e-81 271.8 0.7 6.5e-81 271.4 0.7 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein T2SSE_N PF05157.15 AIM20331.1 - 0.00043 20.5 0.1 0.0019 18.4 0.0 2.1 1 1 1 2 2 2 1 Type II secretion system (T2SS), protein E, N-terminal domain AAA_22 PF13401.6 AIM20331.1 - 0.0016 18.7 0.7 0.009 16.3 0.2 2.4 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 AIM20331.1 - 0.0025 17.8 0.0 0.004 17.2 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 AIM20331.1 - 0.0037 17.7 1.6 0.016 15.6 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain DUF3261 PF11659.8 AIM20331.1 - 0.0041 17.0 0.9 0.014 15.3 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3261) AAA_19 PF13245.6 AIM20331.1 - 0.016 15.5 0.2 0.078 13.3 0.1 1.9 1 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 AIM20331.1 - 0.026 14.1 0.0 0.058 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 AIM20331.1 - 0.029 14.4 0.0 0.053 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 AIM20331.1 - 0.07 13.5 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 AIM20331.1 - 0.09 12.9 0.2 4.7 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 AIM20331.1 - 0.1 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) S-methyl_trans PF02574.16 AIM20331.1 - 0.11 12.2 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Homocysteine S-methyltransferase AAA_11 PF13086.6 AIM20331.1 - 0.14 11.9 0.1 0.35 10.6 0.0 1.5 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 AIM20331.1 - 0.14 12.7 0.0 3.2 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 AIM20331.1 - 0.26 11.7 0.1 0.47 10.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain N_methyl PF07963.12 AIM20332.1 - 5.7e-09 35.2 4.1 5.7e-09 35.2 4.1 2.0 2 0 0 2 2 2 1 Prokaryotic N-terminal methylation motif Pilin PF00114.19 AIM20332.1 - 6e-05 23.9 0.2 7.1e-05 23.7 0.2 1.1 1 0 0 1 1 1 1 Pilin (bacterial filament) QRPTase_C PF01729.19 AIM20333.1 - 3.8e-61 205.7 0.3 4.9e-61 205.4 0.3 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 AIM20333.1 - 1.1e-26 92.7 0.0 3e-26 91.3 0.0 1.7 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain PG_binding_1 PF01471.18 AIM20333.1 - 0.0029 17.8 0.2 0.0063 16.7 0.2 1.5 1 0 0 1 1 1 1 Putative peptidoglycan binding domain IMPDH PF00478.25 AIM20333.1 - 0.0051 15.9 0.0 0.0051 15.9 0.0 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Amidase_2 PF01510.25 AIM20334.1 - 2.4e-28 99.1 0.0 3e-28 98.8 0.0 1.1 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase AmpE PF17113.5 AIM20335.1 - 1.2e-158 526.9 13.3 1.4e-158 526.7 13.3 1.0 1 0 0 1 1 1 1 Regulatory signalling modulator protein AmpE DUF962 PF06127.11 AIM20335.1 - 0.095 12.8 5.0 3.1 7.9 1.5 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF962) SAYSvFN PF10260.9 AIM20335.1 - 0.36 10.8 3.0 1.3 9.0 3.0 2.0 1 0 0 1 1 1 0 Uncharacterized conserved domain (SAYSvFN) Voltage_CLC PF00654.20 AIM20336.1 - 7.8e-92 308.2 45.4 1.8e-89 300.5 38.9 2.0 1 1 1 2 2 2 2 Voltage gated chloride channel DUF4338 PF14236.6 AIM20336.1 - 0.032 13.5 0.1 0.065 12.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4338) Fe-S_biosyn PF01521.20 AIM20337.1 - 1.9e-20 73.1 0.0 2.2e-20 72.9 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis UPF0126 PF03458.13 AIM20338.1 - 1.4e-42 143.4 30.0 8.6e-24 83.2 8.0 2.4 3 0 0 3 3 3 2 UPF0126 domain AzlD PF05437.12 AIM20338.1 - 0.0079 16.3 1.9 0.0079 16.3 1.9 3.1 2 2 0 3 3 3 1 Branched-chain amino acid transport protein (AzlD) Peripla_BP_2 PF01497.18 AIM20339.1 - 7.2e-20 71.6 0.0 9.2e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein YAcAr PF10686.9 AIM20339.1 - 0.0012 18.8 0.0 0.0043 17.0 0.0 1.9 1 0 0 1 1 1 1 YspA, cpYpsA-related SLOG family DRTGG PF07085.12 AIM20339.1 - 0.024 14.4 0.0 0.19 11.5 0.0 2.3 3 0 0 3 3 3 0 DRTGG domain PNP_UDP_1 PF01048.20 AIM20340.1 - 1.2e-48 165.4 5.5 1.3e-48 165.3 5.5 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily HD_assoc PF13286.6 AIM20341.1 - 6.2e-12 45.9 1.5 4.2e-05 24.0 0.4 3.1 2 1 1 3 3 3 2 Phosphohydrolase-associated domain HD PF01966.22 AIM20341.1 - 7.9e-10 39.0 0.0 2.1e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 HD domain Trypsin_2 PF13365.6 AIM20342.1 - 1.2e-29 104.2 0.3 2.1e-29 103.3 0.3 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ PF00595.24 AIM20342.1 - 9.6e-26 90.0 8.4 1.2e-12 48.0 0.2 3.3 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 AIM20342.1 - 3.6e-24 84.9 0.6 3.4e-14 52.9 0.0 2.7 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 AIM20342.1 - 1.5e-21 76.0 2.3 1e-10 41.3 0.3 2.9 3 0 0 3 3 3 2 PDZ domain Trypsin PF00089.26 AIM20342.1 - 4.8e-19 69.1 0.1 7.9e-19 68.3 0.1 1.3 1 0 0 1 1 1 1 Trypsin PDZ_1 PF12812.7 AIM20342.1 - 0.00084 19.3 0.0 0.24 11.5 0.0 2.8 2 0 0 2 2 2 1 PDZ-like domain Tricorn_PDZ PF14685.6 AIM20342.1 - 0.00088 19.2 1.5 0.86 9.6 0.2 3.4 3 0 0 3 3 3 2 Tricorn protease PDZ domain DUF3394 PF11874.8 AIM20342.1 - 0.072 12.8 0.6 2 8.1 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3394) Peptidase_S46 PF10459.9 AIM20342.1 - 0.097 11.3 0.4 0.27 9.8 0.3 1.6 2 0 0 2 2 2 0 Peptidase S46 DUF2222 PF09984.9 AIM20343.1 - 8.6e-58 194.4 0.1 1.9e-57 193.3 0.1 1.6 1 0 0 1 1 1 1 Uncharacterised signal transduction histidine kinase domain (DUF2222) HATPase_c PF02518.26 AIM20343.1 - 6.3e-30 104.0 0.7 1.1e-29 103.1 0.7 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AIM20343.1 - 1.1e-27 96.4 3.0 5.7e-27 94.1 0.2 3.0 3 0 0 3 3 3 1 Response regulator receiver domain HisKA PF00512.25 AIM20343.1 - 2.2e-20 72.4 7.5 9.3e-20 70.4 0.1 3.9 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain Hpt PF01627.23 AIM20343.1 - 7.1e-11 42.2 1.2 7.1e-11 42.2 1.2 2.5 2 0 0 2 2 2 1 Hpt domain HAMP PF00672.25 AIM20343.1 - 1.1e-07 32.1 0.5 4.2e-07 30.2 0.5 2.2 1 0 0 1 1 1 1 HAMP domain HydF_dimer PF18128.1 AIM20343.1 - 0.11 12.6 0.1 0.9 9.6 0.0 2.6 3 0 0 3 3 3 0 Hydrogen maturase F dimerization domain Flg_hook PF02120.16 AIM20343.1 - 0.55 10.2 5.6 0.68 9.9 1.3 3.1 3 0 0 3 3 3 0 Flagellar hook-length control protein FliK DUF1640 PF07798.11 AIM20343.1 - 3.3 7.7 8.1 0.22 11.5 2.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) tRNA_U5-meth_tr PF05958.11 AIM20344.1 - 2.6e-26 92.4 0.0 3.6e-25 88.7 0.0 2.2 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase TRAM PF01938.20 AIM20344.1 - 1.7e-13 50.4 0.1 2.7e-13 49.7 0.1 1.4 1 0 0 1 1 1 1 TRAM domain Methyltransf_31 PF13847.6 AIM20344.1 - 6e-11 42.4 0.0 1.5e-10 41.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 AIM20344.1 - 2e-07 31.6 0.0 5e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 AIM20344.1 - 2.2e-06 27.6 0.0 4e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 AIM20344.1 - 3.7e-05 22.9 0.0 6.5e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Cons_hypoth95 PF03602.15 AIM20344.1 - 9.6e-05 22.1 0.0 0.0002 21.1 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.16 AIM20344.1 - 0.00012 21.9 0.0 0.0002 21.2 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 AIM20344.1 - 0.00019 21.0 0.1 0.00035 20.2 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 AIM20344.1 - 0.00078 20.0 0.0 0.0038 17.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 AIM20344.1 - 0.005 16.2 0.0 0.0083 15.4 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 AIM20344.1 - 0.024 14.5 0.0 0.063 13.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DHDPS PF00701.22 AIM20344.1 - 0.088 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family Methyltransf_4 PF02390.17 AIM20344.1 - 0.14 11.6 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase DOT1 PF08123.13 AIM20344.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 HD_4 PF13328.6 AIM20345.1 - 6.8e-43 146.1 0.8 1.4e-42 145.1 0.8 1.5 1 0 0 1 1 1 1 HD domain RelA_SpoT PF04607.17 AIM20345.1 - 9.3e-37 125.9 0.0 2.4e-36 124.6 0.0 1.8 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins TGS PF02824.21 AIM20345.1 - 1.6e-21 76.1 0.1 6.2e-21 74.2 0.0 2.1 2 0 0 2 2 2 1 TGS domain ACT_4 PF13291.6 AIM20345.1 - 2.3e-18 66.5 1.3 6.1e-18 65.2 1.3 1.7 1 0 0 1 1 1 1 ACT domain ACT PF01842.25 AIM20345.1 - 1.2e-10 41.0 0.2 3.6e-10 39.4 0.2 1.9 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 AIM20345.1 - 0.091 12.8 0.0 0.3 11.1 0.0 1.9 1 0 0 1 1 1 0 ACT domain Prok-JAB PF14464.6 AIM20345.1 - 0.11 12.3 0.3 0.76 9.6 0.0 2.3 1 1 1 2 2 2 0 Prokaryotic homologs of the JAB domain Latarcin PF10279.9 AIM20345.1 - 1.8 9.0 4.9 9.7 6.7 0.6 2.9 3 0 0 3 3 3 0 Latarcin precursor MazG PF03819.17 AIM20346.1 - 2e-37 127.2 2.2 8.7e-27 93.1 0.0 2.5 2 0 0 2 2 2 2 MazG nucleotide pyrophosphohydrolase domain PRA-PH PF01503.17 AIM20346.1 - 1.9e-10 41.0 0.3 3.5e-05 24.2 0.0 2.4 2 0 0 2 2 2 2 Phosphoribosyl-ATP pyrophosphohydrolase MazG-like PF12643.7 AIM20346.1 - 0.0079 16.4 0.1 1.5 9.1 0.0 2.6 2 0 0 2 2 2 1 MazG-like family FAD-SLDH PF12318.8 AIM20346.1 - 0.054 13.6 1.5 0.085 12.9 0.4 1.8 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase CDPS PF16715.5 AIM20346.1 - 0.12 12.0 1.3 0.5 10.0 0.2 2.3 2 0 0 2 2 2 0 Cyclodipeptide synthase Herpes_UL92 PF03048.14 AIM20346.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.6 2 0 0 2 2 2 0 UL92 family CTP_synth_N PF06418.14 AIM20347.1 - 1.6e-125 417.8 0.1 2.1e-125 417.4 0.1 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 AIM20347.1 - 4.6e-64 215.7 0.0 8.7e-64 214.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AIM20347.1 - 2.1e-09 37.5 0.5 3.1e-08 33.6 0.1 2.6 2 1 0 2 2 2 1 Peptidase C26 CbiA PF01656.23 AIM20347.1 - 0.01 15.9 0.0 0.018 15.1 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Enolase_C PF00113.22 AIM20348.1 - 3.3e-140 466.4 2.8 4.2e-140 466.1 2.8 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 AIM20348.1 - 1.8e-58 196.3 0.3 3.7e-58 195.3 0.3 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 AIM20348.1 - 1.5e-06 27.9 0.0 3.8e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 AIM20348.1 - 0.00016 21.0 0.6 0.0014 17.9 0.1 2.2 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus Pyr_redox_2 PF07992.14 AIM20349.1 - 7.4e-10 38.5 0.0 4.5e-08 32.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AIM20349.1 - 0.071 12.4 0.1 0.15 11.3 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 AIM20349.1 - 0.11 11.3 0.1 0.16 10.8 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.27 AIM20349.1 - 0.19 12.3 0.0 0.41 11.2 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF1641 PF07849.11 AIM20350.1 - 0.0077 16.1 0.7 0.014 15.2 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1641) Cys_Met_Meta_PP PF01053.20 AIM20351.1 - 9.8e-140 465.4 0.0 1.1e-139 465.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 AIM20351.1 - 1e-09 37.8 0.0 1.9e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 AIM20351.1 - 1.9e-09 37.2 0.0 2.7e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.11 AIM20351.1 - 6.7e-08 31.5 0.0 1e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase DegT_DnrJ_EryC1 PF01041.17 AIM20351.1 - 2.4e-06 27.1 0.2 2.8e-05 23.6 0.2 2.0 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 AIM20351.1 - 1e-05 25.0 0.1 3e-05 23.4 0.1 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase SelA PF03841.13 AIM20351.1 - 0.12 11.3 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase AA_permease PF00324.21 AIM20352.1 - 1.6e-104 350.2 50.5 1.9e-104 349.9 50.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 AIM20352.1 - 2.7e-43 148.4 54.5 3.3e-43 148.1 54.5 1.0 1 0 0 1 1 1 1 Amino acid permease Spore_permease PF03845.13 AIM20352.1 - 0.75 8.6 27.0 0.019 13.8 13.9 2.9 2 2 0 2 2 2 0 Spore germination protein Lyase_aromatic PF00221.19 AIM20353.1 - 1.8e-187 623.6 7.2 2.1e-187 623.4 7.2 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase Urocanase_C PF17392.2 AIM20354.1 - 1.7e-93 311.6 0.1 3e-93 310.7 0.1 1.4 1 0 0 1 1 1 1 Urocanase C-terminal domain Urocanase PF01175.18 AIM20354.1 - 9.8e-89 296.5 0.0 1.4e-88 296.1 0.0 1.2 1 0 0 1 1 1 1 Urocanase Rossmann-like domain Urocanase_N PF17391.2 AIM20354.1 - 2.7e-63 211.4 0.0 4.7e-63 210.5 0.0 1.4 1 0 0 1 1 1 1 Urocanase N-terminal domain MFS_1 PF07690.16 AIM20355.1 - 3.8e-51 174.1 58.3 2.8e-37 128.4 24.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AIM20355.1 - 1.1e-23 83.9 29.7 1.3e-22 80.3 5.6 2.1 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 AIM20355.1 - 1.5e-07 31.1 5.7 1.5e-07 31.1 5.7 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 AIM20355.1 - 0.0029 16.1 3.4 0.0029 16.1 3.4 3.0 2 1 1 3 3 3 2 Fungal trichothecene efflux pump (TRI12) TMEM43 PF07787.12 AIM20355.1 - 9.6 5.5 10.2 1 8.7 1.2 2.7 3 0 0 3 3 3 0 Transmembrane protein 43 Fer4_14 PF13394.6 AIM20356.1 - 1.7e-13 50.8 0.3 1e-12 48.2 0.3 2.0 1 1 0 1 1 1 1 4Fe-4S single cluster domain Radical_SAM PF04055.21 AIM20356.1 - 1.9e-08 34.9 0.7 3.4e-08 34.1 0.6 1.6 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 AIM20356.1 - 1e-07 32.3 0.2 2.1e-07 31.3 0.2 1.5 1 1 0 1 1 1 1 4Fe-4S single cluster domain Acetyltransf_9 PF13527.7 AIM20357.1 - 5.5e-17 62.0 0.1 7.9e-17 61.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AIM20357.1 - 2.2e-08 34.3 0.1 2.9e-08 33.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AIM20357.1 - 0.00014 21.8 0.0 0.00021 21.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AIM20357.1 - 0.00048 20.5 0.1 0.00097 19.5 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 AIM20357.1 - 0.0011 18.9 0.2 1.8 8.6 0.0 2.4 1 1 1 2 2 2 2 ESCO1/2 acetyl-transferase FR47 PF08445.10 AIM20357.1 - 0.018 15.0 0.1 0.033 14.2 0.1 1.5 1 0 0 1 1 1 0 FR47-like protein PTPS PF01242.19 AIM20358.1 - 2.7e-35 121.0 0.0 3e-35 120.9 0.0 1.0 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase Flavodoxin_1 PF00258.25 AIM20359.1 - 3.1e-31 108.5 0.2 8.2e-31 107.1 0.2 1.8 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 AIM20359.1 - 7.4e-29 100.9 0.0 8.8e-28 97.4 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 AIM20359.1 - 2.4e-20 73.2 0.0 6.3e-20 71.8 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Mito_fiss_reg PF05308.11 AIM20359.1 - 0.11 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator NIR_SIR PF01077.22 AIM20360.1 - 1.2e-52 177.6 0.0 2.2e-47 160.5 0.1 2.2 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 AIM20360.1 - 1.9e-31 107.7 0.0 1.6e-14 53.5 0.0 2.8 3 0 0 3 3 3 2 Nitrite/Sulfite reductase ferredoxin-like half domain PAPS_reduct PF01507.19 AIM20361.1 - 9.6e-49 165.7 0.0 1.1e-48 165.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Peptidase_M28 PF04389.17 AIM20362.1 - 4.9e-33 114.5 0.0 6.5e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.14 AIM20362.1 - 3.2e-07 29.7 0.0 1.1e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.28 AIM20362.1 - 0.0002 21.2 0.0 0.00025 20.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF4910 PF16254.5 AIM20362.1 - 0.066 12.1 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4910) TP_methylase PF00590.20 AIM20363.1 - 2.3e-50 171.5 3.2 4.3e-50 170.6 3.2 1.5 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 AIM20363.1 - 4.3e-28 97.8 0.3 2.5e-27 95.3 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding CysG_dimeriser PF10414.9 AIM20363.1 - 3.5e-22 77.9 5.4 1.4e-21 76.0 5.2 2.3 2 0 0 2 2 2 1 Sirohaem synthase dimerisation region Sirohm_synth_M PF14824.6 AIM20363.1 - 2.4e-08 33.3 0.1 6e-08 32.0 0.1 1.7 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central DUF3460 PF11943.8 AIM20363.1 - 0.24 11.7 0.2 0.52 10.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3460) PAPS_reduct PF01507.19 AIM20364.1 - 5.1e-66 222.0 0.0 6.2e-66 221.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family GTP_EFTU PF00009.27 AIM20365.1 - 2.3e-44 151.2 0.0 3.1e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 AIM20365.1 - 5.2e-08 33.0 0.0 4.4e-06 26.8 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 AIM20365.1 - 2.7e-05 24.5 0.1 5.7e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 SRPRB PF09439.10 AIM20365.1 - 0.014 14.8 0.1 0.64 9.4 0.1 2.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Roc PF08477.13 AIM20365.1 - 0.037 14.3 0.0 7.7 6.8 0.0 2.3 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 AIM20365.1 - 0.1 12.1 0.0 0.64 9.5 0.0 2.2 2 1 0 2 2 2 0 Ferrous iron transport protein B APS_kinase PF01583.20 AIM20366.1 - 2.1e-73 245.4 0.0 2.5e-73 245.2 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 AIM20366.1 - 3.3e-07 30.5 0.0 5e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AIM20366.1 - 2.2e-05 25.0 0.0 3.3e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 AIM20366.1 - 0.0038 16.7 0.0 0.0052 16.3 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 CbiA PF01656.23 AIM20366.1 - 0.0042 17.1 0.0 0.0059 16.7 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_29 PF13555.6 AIM20366.1 - 0.0059 16.3 1.0 0.0077 16.0 0.0 1.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AIM20366.1 - 0.0099 16.3 0.3 0.015 15.7 0.3 1.6 1 1 0 1 1 1 1 AAA ATPase domain ParA PF10609.9 AIM20366.1 - 0.025 14.0 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase ABC_tran PF00005.27 AIM20366.1 - 0.035 14.6 0.0 0.065 13.8 0.0 1.5 2 0 0 2 2 2 0 ABC transporter PRK PF00485.18 AIM20366.1 - 0.051 13.3 0.0 0.077 12.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.6 AIM20366.1 - 0.064 13.7 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 AIM20366.1 - 0.068 12.8 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain CPT PF07931.12 AIM20366.1 - 0.089 12.6 1.1 0.9 9.4 1.1 2.1 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_22 PF13401.6 AIM20366.1 - 0.16 12.2 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ploopntkinase1 PF18748.1 AIM20366.1 - 0.19 11.2 0.0 11 5.5 0.0 2.1 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 AAA_23 PF13476.6 AIM20366.1 - 0.19 12.2 0.0 0.24 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF3561 PF12084.8 AIM20367.1 - 3.7e-47 158.8 9.7 4.1e-47 158.6 9.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3561) ABC_tran PF00005.27 AIM20368.1 - 1.2e-34 119.8 0.0 1.6e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIM20368.1 - 9.8e-11 42.0 0.1 9.1e-05 22.4 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIM20368.1 - 6e-09 35.7 0.2 2.7e-08 33.5 0.2 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AIM20368.1 - 0.00023 20.8 0.0 0.00045 19.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 AIM20368.1 - 0.00026 20.9 0.0 0.0047 16.7 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_16 PF13191.6 AIM20368.1 - 0.00037 20.9 0.0 0.00057 20.3 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 AIM20368.1 - 0.0007 19.4 0.0 0.0011 18.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 AIM20368.1 - 0.0034 17.9 0.0 0.0051 17.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AIM20368.1 - 0.0035 17.2 0.1 0.0094 15.9 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_13 PF13166.6 AIM20368.1 - 0.0068 15.1 0.0 0.085 11.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 AIM20368.1 - 0.013 15.7 0.0 0.031 14.4 0.0 1.7 2 0 0 2 2 1 0 AAA domain ABC_ATPase PF09818.9 AIM20368.1 - 0.016 14.0 0.1 1.7 7.4 0.1 2.9 2 1 0 2 2 2 0 Predicted ATPase of the ABC class NTPase_1 PF03266.15 AIM20368.1 - 0.021 14.7 0.1 0.045 13.7 0.1 1.5 1 0 0 1 1 1 0 NTPase NACHT PF05729.12 AIM20368.1 - 0.024 14.5 0.0 0.059 13.3 0.0 1.7 1 0 0 1 1 1 0 NACHT domain PhoH PF02562.16 AIM20368.1 - 0.024 14.1 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.6 AIM20368.1 - 0.026 14.3 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AIM20368.1 - 0.029 14.7 0.1 0.039 14.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 AIM20368.1 - 0.044 14.1 0.1 0.055 13.8 0.1 1.4 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 AIM20368.1 - 0.05 13.8 0.4 2 8.7 0.1 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ATP_bind_1 PF03029.17 AIM20368.1 - 0.062 13.1 0.1 0.21 11.3 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 AIM20368.1 - 0.063 13.8 0.1 0.14 12.7 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AIM20368.1 - 0.095 12.3 0.1 0.4 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 AIM20368.1 - 0.096 13.1 0.2 1.2 9.5 0.2 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 AIM20368.1 - 0.099 12.4 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase_2 PF01637.18 AIM20368.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Rad17 PF03215.15 AIM20368.1 - 0.13 12.2 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain CobU PF02283.16 AIM20368.1 - 0.13 11.8 0.1 4.4 6.8 0.0 2.3 2 1 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase DLIC PF05783.11 AIM20368.1 - 0.17 10.7 0.0 0.27 10.0 0.0 1.3 1 1 0 1 1 1 0 Dynein light intermediate chain (DLIC) BPD_transp_1 PF00528.22 AIM20369.1 - 1.7e-22 80.1 5.5 1.7e-22 80.1 5.5 1.6 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF3433 PF11915.8 AIM20369.1 - 2.6 8.6 7.3 2.6 8.6 0.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3433) SBP_bac_3 PF00497.20 AIM20370.1 - 6.2e-61 205.7 0.9 7e-61 205.5 0.9 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 AIM20370.1 - 4.1e-11 43.1 0.1 2.3e-09 37.4 0.1 2.3 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site DivIC PF04977.15 AIM20371.1 - 3.1e-31 107.0 0.0 3.9e-31 106.6 0.0 1.1 1 0 0 1 1 1 1 Septum formation initiator IspD PF01128.19 AIM20372.1 - 4.1e-81 271.9 0.1 4.6e-81 271.8 0.1 1.0 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NTP_transf_3 PF12804.7 AIM20372.1 - 2e-14 54.3 3.1 3.3e-14 53.6 3.2 1.4 1 1 0 1 1 1 1 MobA-like NTP transferase domain YgbB PF02542.16 AIM20373.1 - 2.9e-66 222.6 0.0 3.2e-66 222.4 0.0 1.0 1 0 0 1 1 1 1 YgbB family TruD PF01142.18 AIM20374.1 - 2.3e-59 201.3 0.0 2e-40 138.9 0.0 2.0 1 1 1 2 2 2 2 tRNA pseudouridine synthase D (TruD) SurE PF01975.17 AIM20375.1 - 3.1e-57 193.5 0.1 3.9e-57 193.2 0.1 1.1 1 0 0 1 1 1 1 Survival protein SurE PCMT PF01135.19 AIM20376.1 - 5.6e-77 258.2 0.0 6.8e-77 257.9 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 AIM20376.1 - 1.5e-06 27.5 0.0 2e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 AIM20376.1 - 2.4e-05 24.9 0.0 4.9e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AIM20376.1 - 2.7e-05 24.0 0.0 4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AIM20376.1 - 0.0027 18.3 0.0 0.0054 17.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AIM20376.1 - 0.0073 16.2 0.0 0.012 15.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 AIM20376.1 - 0.013 14.8 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase GCD14 PF08704.10 AIM20376.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit NodS PF05401.11 AIM20376.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_32 PF13679.6 AIM20376.1 - 0.12 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 AIM20376.1 - 0.16 11.0 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Peptidase_M23 PF01551.22 AIM20378.1 - 5.1e-32 109.9 0.6 1.5e-31 108.4 0.6 1.8 1 0 0 1 1 1 1 Peptidase family M23 LysM PF01476.20 AIM20378.1 - 1.6e-10 40.9 0.2 4.4e-10 39.5 0.1 1.8 2 0 0 2 2 2 1 LysM domain Biotin_lipoyl_2 PF13533.6 AIM20378.1 - 0.0015 18.3 0.0 0.18 11.7 0.0 3.0 3 0 0 3 3 3 1 Biotin-lipoyl like Sigma70_r2 PF04542.14 AIM20379.1 - 1.6e-21 75.8 0.6 3.4e-21 74.8 0.2 1.8 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r3 PF04539.16 AIM20379.1 - 2.3e-21 75.7 6.8 9.9e-21 73.6 1.5 2.8 3 0 0 3 3 3 1 Sigma-70 region 3 Sigma70_r4 PF04545.16 AIM20379.1 - 3.8e-17 61.5 3.7 2.5e-15 55.7 2.8 2.6 2 0 0 2 2 2 2 Sigma-70, region 4 Sigma70_r1_2 PF00140.20 AIM20379.1 - 1.6e-11 44.0 0.1 5.3e-11 42.3 0.1 2.0 1 0 0 1 1 1 1 Sigma-70 factor, region 1.2 MutS_V PF00488.21 AIM20380.1 - 5.2e-90 300.5 0.3 9.4e-90 299.7 0.3 1.4 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.20 AIM20380.1 - 3.8e-43 146.3 0.0 1e-42 144.9 0.0 1.8 2 0 0 2 2 2 1 MutS domain I MutS_III PF05192.18 AIM20380.1 - 3.8e-40 138.2 1.9 5.8e-40 137.6 0.8 1.9 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 AIM20380.1 - 1.7e-34 119.1 0.0 3.5e-34 118.0 0.0 1.6 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 AIM20380.1 - 7.6e-29 99.9 0.0 1.8e-28 98.7 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV Lebercilin PF15619.6 AIM20380.1 - 0.097 12.3 0.3 0.27 10.9 0.3 1.7 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease TPR_14 PF13428.6 AIM20380.1 - 3.3 8.8 0.0 3.3 8.8 0.0 4.6 6 0 0 6 6 6 0 Tetratricopeptide repeat SGL PF08450.12 AIM20381.1 - 0.0029 17.2 0.0 0.59 9.7 0.0 2.6 1 1 2 3 3 3 3 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 AIM20381.1 - 0.14 12.3 4.0 16 5.8 0.0 3.9 4 0 0 4 4 4 0 NHL repeat PQQ PF01011.21 AIM20381.1 - 1.5 8.9 3.6 1.4 9.0 0.1 2.7 3 0 0 3 3 3 0 PQQ enzyme repeat Aldo_ket_red PF00248.21 AIM20382.1 - 2.9e-76 256.5 0.0 3.3e-76 256.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family adh_short_C2 PF13561.6 AIM20383.1 - 6.8e-66 222.2 1.9 8.4e-66 221.9 1.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AIM20383.1 - 3.5e-51 173.5 0.7 4.1e-51 173.2 0.7 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AIM20383.1 - 3.7e-13 49.8 0.6 4.7e-13 49.4 0.6 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AIM20383.1 - 0.0054 16.2 0.1 0.0076 15.7 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family BAT PF15915.5 AIM20383.1 - 0.043 13.7 0.8 0.07 13.0 0.8 1.3 1 0 0 1 1 1 0 GAF and HTH_10 associated domain FAD_oxidored PF12831.7 AIM20383.1 - 4.8 6.4 6.9 6.8 5.9 6.9 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase LysR_substrate PF03466.20 AIM20384.1 - 9.8e-37 126.3 1.6 9.8e-37 126.3 1.6 1.6 2 1 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AIM20384.1 - 7.1e-20 70.7 1.8 1.6e-19 69.6 1.8 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AIM20384.1 - 0.0053 16.5 0.5 0.015 15.1 0.5 1.8 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain MarR_2 PF12802.7 AIM20384.1 - 0.021 14.7 0.1 0.049 13.5 0.1 1.5 1 0 0 1 1 1 0 MarR family HTH_20 PF12840.7 AIM20384.1 - 0.031 14.3 0.1 0.073 13.1 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 AIM20384.1 - 0.061 13.3 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain PIN7 PF18475.1 AIM20384.1 - 0.085 13.5 0.0 0.13 12.9 0.0 1.3 1 0 0 1 1 1 0 PIN domain PTS_EIIC PF02378.18 AIM20385.1 - 1.1e-42 146.3 30.9 1.1e-42 146.3 30.9 1.5 2 0 0 2 2 2 1 Phosphotransferase system, EIIC Glyco_hydro_1 PF00232.18 AIM20386.1 - 1.2e-129 432.7 0.0 1.3e-129 432.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Cellulase PF00150.18 AIM20386.1 - 0.0014 18.1 0.0 0.0023 17.4 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) HTH_18 PF12833.7 AIM20387.1 - 1.4e-18 66.9 0.0 2.5e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AIM20387.1 - 6e-13 48.5 0.0 9.4e-07 28.8 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Cupin_2 PF07883.11 AIM20387.1 - 2.3e-09 36.8 0.1 4e-09 36.1 0.1 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 AIM20387.1 - 2.3e-08 34.0 0.2 3.8e-08 33.3 0.2 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain JmjC PF02373.22 AIM20387.1 - 0.00071 20.0 0.0 0.0017 18.8 0.0 1.7 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_3 PF05899.12 AIM20387.1 - 0.00091 18.9 0.1 0.0032 17.1 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF861) ARD PF03079.14 AIM20387.1 - 0.0024 18.0 1.1 0.0059 16.8 0.8 1.8 1 1 0 1 1 1 1 ARD/ARD' family EutQ PF06249.12 AIM20387.1 - 0.013 15.2 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ Cupin_7 PF12973.7 AIM20387.1 - 0.021 14.8 0.1 0.036 14.0 0.1 1.3 1 0 0 1 1 1 0 ChrR Cupin-like domain AraC_binding_2 PF14525.6 AIM20387.1 - 0.023 14.4 0.0 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 AraC-binding-like domain Cupin_6 PF12852.7 AIM20387.1 - 0.026 14.2 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 Cupin Lyx_isomer PF07385.12 AIM20387.1 - 0.054 12.7 0.0 0.085 12.1 0.0 1.3 1 0 0 1 1 1 0 D-lyxose isomerase YdjC PF04794.12 AIM20388.1 - 2.4e-59 201.2 0.1 2.8e-59 201.0 0.1 1.0 1 0 0 1 1 1 1 YdjC-like protein MFS_1 PF07690.16 AIM20389.1 - 2.6e-34 118.7 60.0 5.3e-19 68.3 32.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 AIM20389.1 - 2.4e-06 27.1 32.7 2.4e-06 27.1 32.7 1.4 1 1 1 2 2 2 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 AIM20389.1 - 0.0004 19.4 31.5 0.012 14.6 14.9 4.0 1 1 3 4 4 4 2 Sugar (and other) transporter MFS_1_like PF12832.7 AIM20389.1 - 0.15 10.9 29.8 1.1 8.1 13.0 2.5 1 1 1 2 2 2 0 MFS_1 like family OATP PF03137.20 AIM20389.1 - 4.3 5.5 12.5 2.2 6.5 0.3 3.3 2 2 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family CinA PF02464.17 AIM20390.1 - 2.5e-57 192.8 1.0 2.8e-57 192.6 1.0 1.0 1 0 0 1 1 1 1 Competence-damaged protein RecA PF00154.21 AIM20391.1 - 4e-142 472.3 3.0 4.8e-142 472.1 3.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Rad51 PF08423.11 AIM20391.1 - 1.2e-12 47.7 0.8 3.6e-12 46.1 0.8 1.6 1 1 0 1 1 1 1 Rad51 ATPase PF06745.13 AIM20391.1 - 1.7e-09 37.4 0.3 2.7e-08 33.5 0.3 2.5 1 1 0 1 1 1 1 KaiC AAA_24 PF13479.6 AIM20391.1 - 4.2e-05 23.3 0.0 8.5e-05 22.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 AIM20391.1 - 4.3e-05 23.5 0.0 0.00011 22.2 0.0 1.8 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_25 PF13481.6 AIM20391.1 - 0.00042 20.0 0.2 0.045 13.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AIM20391.1 - 0.00053 20.4 0.0 0.00095 19.6 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_35 PF14516.6 AIM20391.1 - 0.011 14.7 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain CbiA PF01656.23 AIM20391.1 - 0.011 15.8 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain PAXNEB PF05625.11 AIM20391.1 - 0.017 14.3 0.6 0.026 13.7 0.6 1.2 1 0 0 1 1 1 0 PAXNEB protein MobB PF03205.14 AIM20391.1 - 0.03 14.2 0.0 0.11 12.3 0.0 1.9 1 1 1 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B CobU PF02283.16 AIM20391.1 - 0.041 13.5 0.0 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_14 PF13173.6 AIM20391.1 - 0.047 13.7 0.0 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 AIM20391.1 - 0.048 14.1 0.1 0.097 13.1 0.1 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TK PF00265.18 AIM20391.1 - 0.066 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Thymidine kinase AAA_22 PF13401.6 AIM20391.1 - 0.1 12.9 0.0 0.22 11.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain RecX PF02631.16 AIM20392.1 - 3.3e-32 111.5 1.3 5.6e-32 110.8 0.5 1.7 2 0 0 2 2 2 1 RecX family tRNA-synt_2c PF01411.19 AIM20393.1 - 2.8e-236 785.4 0.0 3.8e-236 784.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) DHHA1 PF02272.19 AIM20393.1 - 1e-30 107.0 2.7 1e-30 107.0 2.7 2.0 2 0 0 2 2 2 1 DHHA1 domain tRNA_SAD PF07973.14 AIM20393.1 - 2.5e-18 65.9 0.1 8e-18 64.3 0.1 2.0 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DUF3573 PF12097.8 AIM20393.1 - 0.078 11.8 1.2 0.13 11.0 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Leu_zip PF15294.6 AIM20393.1 - 0.54 9.7 6.7 0.065 12.7 1.6 1.9 2 0 0 2 2 2 0 Leucine zipper DUF3708 PF12501.8 AIM20393.1 - 2.6 7.8 6.7 0.58 9.9 1.3 2.6 3 0 0 3 3 3 0 Phosphate ATP-binding cassette transporter CsrA PF02599.16 AIM20394.1 - 2.3e-27 94.7 1.5 2.6e-27 94.5 1.5 1.0 1 0 0 1 1 1 1 Global regulator protein family S1 PF00575.23 AIM20394.1 - 0.025 14.9 0.6 0.12 12.7 0.4 1.8 1 1 1 2 2 2 0 S1 RNA binding domain GerE PF00196.19 AIM20394.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HAD_2 PF13419.6 AIM20395.1 - 1.1e-29 103.8 0.0 1.2e-29 103.6 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AIM20395.1 - 5e-18 66.2 0.0 1.3e-17 64.8 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AIM20395.1 - 2.1e-07 30.9 0.0 1.4e-06 28.2 0.0 2.2 3 0 0 3 3 3 1 HAD-hyrolase-like HAD PF12710.7 AIM20395.1 - 8.9e-06 26.2 0.1 1.2e-05 25.9 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase SNARE_assoc PF09335.11 AIM20396.1 - 2.4e-08 34.5 4.2 3.8e-08 33.8 4.2 1.4 1 0 0 1 1 1 1 SNARE associated Golgi protein Glu_cys_ligase PF04262.14 AIM20397.1 - 3.7e-174 578.7 0.0 4.5e-174 578.4 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase DnaG_DnaB_bind PF08278.11 AIM20397.1 - 0.18 12.4 2.0 0.26 11.9 0.7 1.8 2 0 0 2 2 2 0 DNA primase DnaG DnaB-binding LuxS PF02664.15 AIM20398.1 - 1.1e-61 207.1 0.1 1.2e-61 206.9 0.1 1.0 1 0 0 1 1 1 1 S-Ribosylhomocysteinase (LuxS) DUF21 PF01595.20 AIM20399.1 - 1.1e-41 142.4 0.6 2e-41 141.6 0.6 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CorC_HlyC PF03471.17 AIM20399.1 - 3.7e-20 71.7 0.1 9.7e-20 70.4 0.1 1.8 1 0 0 1 1 1 1 Transporter associated domain CBS PF00571.28 AIM20399.1 - 5.1e-06 26.8 1.2 0.00033 21.1 0.1 2.9 1 1 1 2 2 2 1 CBS domain Cytochrom_C_asm PF01578.20 AIM20400.1 - 1.2e-43 149.3 21.4 1.2e-43 149.3 21.4 1.4 1 1 0 1 1 1 1 Cytochrome C assembly protein DUF4223 PF13978.6 AIM20400.1 - 0.14 12.1 1.3 0.75 9.8 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4223) DUF3094 PF11293.8 AIM20400.1 - 1.2 8.9 0.0 1.2 8.9 0.0 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3094) SRP54 PF00448.22 AIM20401.1 - 5.3e-75 251.4 0.7 9e-75 250.6 0.7 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 AIM20401.1 - 4.5e-32 110.6 5.6 4.5e-32 110.6 5.6 3.3 4 0 0 4 4 3 1 Signal peptide binding domain SRP54_N PF02881.19 AIM20401.1 - 1.7e-22 79.4 1.9 5.9e-22 77.7 0.2 2.8 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain CbiA PF01656.23 AIM20401.1 - 3.3e-07 30.4 0.0 2.4e-06 27.6 0.0 2.4 2 1 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.12 AIM20401.1 - 1.7e-05 24.2 0.1 3.3e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_30 PF13604.6 AIM20401.1 - 0.00012 21.8 1.3 0.00025 20.9 0.3 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 AIM20401.1 - 0.00064 20.0 0.0 0.0028 17.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 AIM20401.1 - 0.0014 18.3 2.0 0.0074 15.9 2.0 2.0 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Peptidase_C23 PF05379.11 AIM20401.1 - 0.0035 17.4 0.0 10 6.3 0.0 3.4 3 0 0 3 3 3 1 Carlavirus endopeptidase AAA_33 PF13671.6 AIM20401.1 - 0.0036 17.5 0.0 0.0072 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 AIM20401.1 - 0.0054 16.6 0.1 0.0098 15.8 0.1 1.4 1 0 0 1 1 1 1 Helicase AAA_24 PF13479.6 AIM20401.1 - 0.0066 16.2 0.1 0.017 14.9 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_31 PF13614.6 AIM20401.1 - 0.0087 16.0 4.8 0.01 15.8 0.5 2.6 2 1 0 3 3 3 1 AAA domain KTI12 PF08433.10 AIM20401.1 - 0.021 14.3 1.1 0.31 10.4 0.0 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 APS_kinase PF01583.20 AIM20401.1 - 0.029 14.3 0.0 0.096 12.6 0.0 1.9 1 0 0 1 1 1 0 Adenylylsulphate kinase Fe-ADH_2 PF13685.6 AIM20401.1 - 0.075 12.7 0.1 0.27 10.9 0.1 2.0 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase MMR_HSR1 PF01926.23 AIM20401.1 - 0.11 12.6 1.7 0.89 9.7 0.8 2.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase Ribosomal_S16 PF00886.19 AIM20402.1 - 4.9e-24 84.2 0.0 5.9e-24 83.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 RimM PF01782.18 AIM20403.1 - 4.8e-25 87.6 0.0 6.8e-25 87.1 0.0 1.2 1 0 0 1 1 1 1 RimM N-terminal domain PRC PF05239.16 AIM20403.1 - 3.9e-09 36.5 0.1 7.1e-09 35.6 0.1 1.4 1 0 0 1 1 1 1 PRC-barrel domain tRNA_m1G_MT PF01746.21 AIM20404.1 - 3e-71 239.2 0.0 3.6e-71 238.9 0.0 1.1 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Ribosomal_L19 PF01245.20 AIM20405.1 - 1.1e-49 167.0 3.5 1.2e-49 166.8 3.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L19 Ogr_Delta PF04606.12 AIM20406.1 - 3.3e-20 71.8 8.8 4e-20 71.5 8.8 1.1 1 0 0 1 1 1 1 Ogr/Delta-like zinc finger zf-tcix PF14952.6 AIM20406.1 - 0.044 13.4 2.3 1.5 8.5 0.8 2.1 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding Lar_restr_allev PF14354.6 AIM20406.1 - 0.051 14.0 1.4 0.078 13.4 1.4 1.3 1 0 0 1 1 1 0 Restriction alleviation protein Lar DUF3268 PF11672.8 AIM20406.1 - 0.084 13.2 1.7 0.099 13.0 1.7 1.1 1 0 0 1 1 1 0 zinc-finger-containing domain Zn_ribbon_17 PF17120.5 AIM20406.1 - 0.13 11.9 5.6 0.2 11.3 5.5 1.4 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf_CopZ PF18423.1 AIM20406.1 - 0.82 9.7 6.3 0.97 9.4 0.9 2.1 1 1 1 2 2 2 0 Zinc binding domain Phage_lysozyme PF00959.19 AIM20407.1 - 1.7e-19 70.2 0.1 2.1e-19 70.0 0.1 1.1 1 0 0 1 1 1 1 Phage lysozyme Phage_holin_2_3 PF16080.5 AIM20408.1 - 1.9e-13 49.9 0.8 2.3e-13 49.7 0.8 1.1 1 0 0 1 1 1 1 Bacteriophage holin family HP1 Phage_holin_2_4 PF16082.5 AIM20408.1 - 7e-08 32.1 0.1 8.6e-08 31.8 0.1 1.2 1 0 0 1 1 1 1 Bacteriophage holin family, superfamily II-like Phage_holin_2_1 PF04971.12 AIM20408.1 - 2.9e-06 27.2 0.4 4e-06 26.7 0.4 1.3 1 0 0 1 1 1 1 Bacteriophage P21 holin S DUF481 PF04338.12 AIM20409.1 - 2.9e-48 164.7 5.1 3.6e-48 164.4 5.1 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF481 OMP_b-brl PF13505.6 AIM20409.1 - 0.011 15.8 7.9 0.055 13.6 7.9 1.9 1 1 0 1 1 1 0 Outer membrane protein beta-barrel domain DUF5053 PF16476.5 AIM20409.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5053) DAHP_synth_1 PF00793.20 AIM20410.1 - 1.3e-106 355.5 0.0 1.6e-106 355.2 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family PDH PF02153.17 AIM20411.1 - 4.7e-31 107.7 0.0 8.2e-31 106.9 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase CM_2 PF01817.21 AIM20411.1 - 5.6e-21 74.7 0.1 1.5e-20 73.3 0.1 1.8 1 0 0 1 1 1 1 Chorismate mutase type II F420_oxidored PF03807.17 AIM20411.1 - 0.00043 20.8 1.7 0.18 12.4 1.3 3.2 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.13 AIM20411.1 - 0.008 15.8 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family DUF2325 PF10087.9 AIM20411.1 - 0.023 14.8 0.0 0.05 13.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) PDT PF00800.18 AIM20412.1 - 1.7e-61 207.2 0.1 2.3e-61 206.8 0.1 1.2 1 0 0 1 1 1 1 Prephenate dehydratase CM_2 PF01817.21 AIM20412.1 - 7.9e-16 58.2 1.1 1.6e-15 57.2 1.1 1.5 1 0 0 1 1 1 1 Chorismate mutase type II ACT PF01842.25 AIM20412.1 - 0.025 14.4 0.0 0.059 13.1 0.0 1.7 1 0 0 1 1 1 0 ACT domain Ribosomal_S30AE PF02482.19 AIM20413.1 - 7.3e-22 78.0 0.0 9e-22 77.7 0.0 1.1 1 0 0 1 1 1 1 Sigma 54 modulation protein / S30EA ribosomal protein YfiO PF13525.6 AIM20414.1 - 6.6e-83 277.4 6.9 8.1e-83 277.1 6.9 1.0 1 0 0 1 1 1 1 Outer membrane lipoprotein TPR_18 PF13512.6 AIM20414.1 - 1.3e-69 232.9 10.2 1.4e-69 232.8 4.9 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 AIM20414.1 - 0.00036 21.1 1.2 6.7 7.8 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_21 PF09976.9 AIM20414.1 - 0.0045 16.7 1.8 0.054 13.2 0.1 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 AIM20414.1 - 0.0051 17.4 7.8 0.76 10.5 0.3 4.3 4 1 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 AIM20414.1 - 0.0079 16.4 0.2 9 6.6 0.0 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 AIM20414.1 - 0.0094 16.1 0.8 3.4 7.9 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 AIM20414.1 - 0.036 14.6 6.2 0.31 11.6 0.1 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat Herpes_U59 PF04529.12 AIM20414.1 - 0.18 10.8 0.3 0.23 10.5 0.3 1.2 1 0 0 1 1 1 0 Herpesvirus U59 protein PseudoU_synth_2 PF00849.22 AIM20415.1 - 9e-32 110.4 0.2 1.2e-31 110.0 0.2 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase TruB_N PF01509.18 AIM20415.1 - 0.02 15.2 0.1 0.032 14.6 0.1 1.3 1 0 0 1 1 1 0 TruB family pseudouridylate synthase (N terminal domain) CT47 PF15623.6 AIM20415.1 - 0.11 12.3 0.1 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 Cancer/testis gene family 47 Cu-oxidase_4 PF02578.15 AIM20416.1 - 4.1e-79 265.4 0.1 4.7e-79 265.2 0.1 1.0 1 0 0 1 1 1 1 Multi-copper polyphenol oxidoreductase laccase AAA_2 PF07724.14 AIM20417.1 - 5.3e-60 202.4 0.0 2.8e-57 193.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 AIM20417.1 - 4.2e-36 123.0 4.4 4.2e-36 123.0 4.4 2.2 1 1 1 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 AIM20417.1 - 6.1e-27 93.5 1.4 2.3e-26 91.6 0.1 2.8 3 0 0 3 3 2 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.20 AIM20417.1 - 6.3e-27 93.5 4.9 4.5e-14 52.3 0.1 3.1 3 0 0 3 3 2 2 Clp amino terminal domain, pathogenicity island component AAA PF00004.29 AIM20417.1 - 1.1e-26 93.9 0.0 3.2e-13 50.2 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AIM20417.1 - 2.4e-19 69.7 0.0 3.4e-13 49.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AIM20417.1 - 7.4e-14 52.5 2.5 4.7e-05 23.9 0.1 5.4 4 2 1 5 5 5 2 AAA ATPase domain Sigma54_activat PF00158.26 AIM20417.1 - 4.9e-09 36.1 0.0 5e-06 26.3 0.0 2.9 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.6 AIM20417.1 - 4.6e-08 33.4 5.1 0.0091 16.3 0.1 5.0 3 2 0 3 3 3 2 AAA domain TniB PF05621.11 AIM20417.1 - 1.6e-06 27.6 0.1 0.0063 15.9 0.0 4.0 3 1 0 3 3 2 1 Bacterial TniB protein AAA_18 PF13238.6 AIM20417.1 - 1.8e-06 28.5 0.1 0.11 13.0 0.0 4.0 3 0 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 AIM20417.1 - 3.4e-06 26.9 0.0 0.084 12.6 0.0 3.1 3 0 0 3 3 3 2 IstB-like ATP binding protein ATPase_2 PF01637.18 AIM20417.1 - 4.2e-05 23.6 1.2 2 8.2 0.1 4.4 3 3 1 4 4 3 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 AIM20417.1 - 4.8e-05 23.4 0.0 0.62 10.1 0.0 3.0 3 0 0 3 3 2 2 AAA domain RuvB_N PF05496.12 AIM20417.1 - 6.5e-05 22.7 0.9 2.8 7.7 0.0 4.5 4 1 0 4 4 4 2 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 AIM20417.1 - 0.00011 21.7 0.1 0.93 8.8 0.0 3.4 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 AIM20417.1 - 0.00013 21.6 0.0 0.39 10.2 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 AIM20417.1 - 0.00013 21.7 0.0 0.18 11.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 AIM20417.1 - 0.00027 21.3 0.0 1.4 9.3 0.0 3.1 3 0 0 3 3 2 2 RNA helicase NACHT PF05729.12 AIM20417.1 - 0.00055 19.9 0.0 0.11 12.4 0.0 2.8 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.6 AIM20417.1 - 0.00058 20.1 0.6 3.7 7.8 0.0 4.3 4 1 0 4 4 4 1 AAA domain Roc PF08477.13 AIM20417.1 - 0.00062 20.0 0.0 2 8.7 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 AIM20417.1 - 0.00064 19.7 0.0 1.5 8.7 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase TsaE PF02367.17 AIM20417.1 - 0.0015 18.5 0.0 1.6 8.7 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 AIM20417.1 - 0.0019 17.4 0.1 0.5 9.5 0.0 3.0 3 1 0 3 3 3 1 Protein of unknown function (DUF815) AAA_3 PF07726.11 AIM20417.1 - 0.0026 17.6 0.0 1.7 8.5 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 AIM20417.1 - 0.0038 17.7 2.9 2.2 8.8 0.0 3.7 3 1 0 3 3 3 1 ABC transporter ResIII PF04851.15 AIM20417.1 - 0.011 15.7 0.0 8.5 6.3 0.0 3.4 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_29 PF13555.6 AIM20417.1 - 0.013 15.3 0.0 5.5 6.8 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.6 AIM20417.1 - 0.014 15.9 18.4 0.5 10.8 0.0 4.0 2 1 1 3 3 3 0 AAA domain HTH_27 PF13463.6 AIM20417.1 - 0.016 15.7 0.3 0.16 12.5 0.1 2.8 2 0 0 2 2 2 0 Winged helix DNA-binding domain AAA_33 PF13671.6 AIM20417.1 - 0.02 15.0 0.0 13 6.0 0.0 3.0 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 AIM20417.1 - 0.024 13.9 0.0 4.5 6.5 0.0 2.8 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.6 AIM20417.1 - 0.026 14.9 0.0 1.2 9.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain DNA_pol3_delta2 PF13177.6 AIM20417.1 - 0.027 14.3 0.0 6.9 6.4 0.0 2.7 2 0 0 2 2 2 0 DNA polymerase III, delta subunit ATP_bind_1 PF03029.17 AIM20417.1 - 0.029 14.2 0.0 1.4 8.7 0.0 2.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.6 AIM20417.1 - 0.029 13.9 0.0 1.7 8.2 0.0 3.1 3 0 0 3 3 2 0 AAA domain NTPase_1 PF03266.15 AIM20417.1 - 0.034 14.0 0.0 8.1 6.3 0.0 2.9 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.9 AIM20417.1 - 0.081 12.7 0.0 1.8 8.3 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran_CTD PF16326.5 AIM20417.1 - 1.7 9.0 16.7 0.16 12.3 7.9 3.3 2 1 0 2 2 2 0 ABC transporter C-terminal domain EccE PF11203.8 AIM20417.1 - 5.2 7.5 6.9 14 6.0 0.0 3.8 4 1 0 4 4 2 0 Putative type VII ESX secretion system translocon, EccE Aldo_ket_red PF00248.21 AIM20418.1 - 8.7e-54 182.7 1.1 1.3e-51 175.6 1.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family ABC-3 PF00950.17 AIM20418.1 - 0.09 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 ABC 3 transport family LysR_substrate PF03466.20 AIM20419.1 - 1.2e-43 148.9 0.1 1.9e-43 148.3 0.1 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM20419.1 - 1.8e-19 69.4 0.8 1.6e-18 66.4 0.7 2.3 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family Urocanase_N PF17391.2 AIM20419.1 - 0.027 14.2 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 Urocanase N-terminal domain MarR_2 PF12802.7 AIM20419.1 - 0.082 12.8 0.4 1.6 8.6 0.1 2.9 3 0 0 3 3 3 0 MarR family Fe_dep_repress PF01325.19 AIM20419.1 - 0.11 12.8 0.2 0.55 10.5 0.1 2.0 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain MFS_1 PF07690.16 AIM20420.1 - 2e-52 178.3 79.4 3.3e-41 141.4 46.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 AIM20420.1 - 9.3e-17 61.4 46.0 1.1e-16 61.1 46.0 1.0 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 AIM20420.1 - 3.4e-07 29.5 41.6 3.5e-06 26.2 13.7 3.3 1 1 2 3 3 3 3 Sugar (and other) transporter Exo_endo_phos PF03372.23 AIM20421.1 - 3e-07 30.2 1.5 2e-06 27.5 1.5 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 AIM20421.1 - 0.0048 16.7 0.0 0.0097 15.7 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase SLT PF01464.20 AIM20422.1 - 1.5e-28 98.8 0.2 2.9e-28 97.9 0.2 1.5 1 0 0 1 1 1 1 Transglycosylase SLT domain LysM PF01476.20 AIM20422.1 - 1e-25 89.5 1.2 8.9e-13 48.1 0.2 3.4 3 0 0 3 3 3 2 LysM domain OapA PF04225.12 AIM20422.1 - 3.6e-06 27.0 0.6 0.16 12.1 0.0 3.3 2 1 1 3 3 3 2 Opacity-associated protein A LysM-like domain HTH_Tnp_1 PF01527.20 AIM20422.1 - 0.00061 20.1 0.0 0.34 11.3 0.0 2.8 2 0 0 2 2 2 2 Transposase Flagellin_IN PF07196.13 AIM20422.1 - 0.025 14.8 0.7 4.4 7.6 0.1 2.7 2 0 0 2 2 2 0 Flagellin hook IN motif DUF3071 PF11268.8 AIM20422.1 - 0.039 14.0 0.0 0.17 11.9 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3071) HTH_38 PF13936.6 AIM20422.1 - 0.1 12.4 0.1 6.8 6.5 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain MLTD_N PF06474.12 AIM20422.1 - 0.22 11.7 1.3 0.35 11.1 0.3 1.9 2 0 0 2 2 2 0 MltD lipid attachment motif HAGH_C PF16123.5 AIM20423.1 - 1.3e-25 89.7 0.1 1.9e-25 89.1 0.1 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 AIM20423.1 - 3.5e-19 69.6 1.1 5.1e-18 65.8 1.1 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AIM20423.1 - 8.2e-06 25.5 0.5 1.3e-05 24.8 0.5 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 AIM20423.1 - 4.4e-05 23.4 0.0 7.9e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 AIM20423.1 - 0.16 11.4 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain Methyltransf_11 PF08241.12 AIM20424.1 - 4.3e-10 40.1 0.0 6.7e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AIM20424.1 - 0.00065 20.4 0.0 0.001 19.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AIM20424.1 - 0.0094 15.8 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIM20424.1 - 0.021 15.6 0.0 0.031 15.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_29 PF03141.16 AIM20424.1 - 0.022 13.3 0.0 0.047 12.2 0.0 1.3 1 1 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_31 PF13847.6 AIM20424.1 - 0.058 13.2 0.0 0.081 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 AIM20424.1 - 0.094 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family RNase_H PF00075.24 AIM20425.1 - 3.3e-54 183.0 0.0 3.7e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 RNase H RNase_T PF00929.24 AIM20426.1 - 2.7e-41 141.9 0.2 5.4e-41 140.9 0.0 1.5 2 0 0 2 2 2 1 Exonuclease DUF5051 PF16473.5 AIM20426.1 - 7e-08 32.6 0.0 1.8e-07 31.3 0.0 1.7 1 1 0 1 1 1 1 3' exoribonuclease, RNase T-like DNA_pol_A_exo1 PF01612.20 AIM20426.1 - 0.00054 19.7 0.2 0.014 15.1 0.0 2.6 2 1 0 2 2 2 1 3'-5' exonuclease vATP-synt_AC39 PF01992.16 AIM20426.1 - 0.044 13.3 0.0 0.057 12.9 0.0 1.1 1 0 0 1 1 1 0 ATP synthase (C/AC39) subunit TonB_dep_Rec PF00593.24 AIM20427.1 - 1.3e-29 104.4 61.2 5.9e-29 102.3 61.3 1.8 1 1 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AIM20427.1 - 2.6e-19 69.8 1.5 7.7e-19 68.3 1.5 1.9 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain DUF1139 PF06599.11 AIM20427.1 - 0.0063 16.0 0.1 0.012 15.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1139) FAD_binding_9 PF08021.11 AIM20428.1 - 4.7e-38 130.1 0.0 1.4e-37 128.6 0.0 1.8 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain SIP PF04954.13 AIM20428.1 - 3.3e-32 111.5 1.7 5.7e-32 110.7 1.7 1.4 1 0 0 1 1 1 1 Siderophore-interacting protein FAD_binding_6 PF00970.24 AIM20428.1 - 0.013 15.8 0.0 0.078 13.3 0.0 2.1 2 1 0 2 2 2 0 Oxidoreductase FAD-binding domain DUF3225 PF11533.8 AIM20429.1 - 7.3e-59 197.0 0.1 8.1e-59 196.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3225) DUF4440 PF14534.6 AIM20429.1 - 4.8e-09 36.6 0.2 5.8e-09 36.3 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 AIM20429.1 - 1.1e-08 35.4 0.0 1.4e-08 35.1 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 AIM20429.1 - 0.0011 19.6 0.2 0.0013 19.3 0.2 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.6 AIM20429.1 - 0.0038 17.4 0.2 0.0058 16.7 0.2 1.3 1 1 0 1 1 1 1 SnoaL-like domain Lumazine_bd_2 PF12893.7 AIM20429.1 - 0.01 16.5 0.0 0.013 16.1 0.0 1.1 1 0 0 1 1 1 0 Putative lumazine-binding CaMKII_AD PF08332.10 AIM20429.1 - 0.15 12.2 0.1 0.29 11.3 0.1 1.4 1 1 0 1 1 1 0 Calcium/calmodulin dependent protein kinase II association domain Amidase PF01425.21 AIM20430.1 - 2.5e-99 333.3 0.0 3.6e-99 332.8 0.0 1.2 1 0 0 1 1 1 1 Amidase DUF4089 PF13318.6 AIM20431.1 - 1.7e-16 60.4 0.8 2e-16 60.2 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4089) G_glu_transpept PF01019.21 AIM20432.1 - 6.7e-125 417.8 0.0 7.6e-125 417.6 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase SHS2_Rpb7-N PF03876.17 AIM20432.1 - 0.11 12.9 0.0 0.32 11.4 0.0 1.7 1 0 0 1 1 1 0 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 HTH_6 PF01418.17 AIM20433.1 - 1.4e-14 53.8 0.0 3e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain, rpiR family SIS PF01380.22 AIM20433.1 - 2.7e-13 49.9 0.0 3.7e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 SIS domain HTH_Crp_2 PF13545.6 AIM20433.1 - 5.8e-05 23.0 0.1 0.00029 20.7 0.0 2.3 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain LacI PF00356.21 AIM20433.1 - 0.0002 21.1 0.0 0.00051 19.8 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family HTH_IclR PF09339.10 AIM20433.1 - 0.0028 17.4 0.1 0.016 15.0 0.0 2.4 2 0 0 2 2 2 1 IclR helix-turn-helix domain MarR_2 PF12802.7 AIM20433.1 - 0.0059 16.5 0.2 0.018 14.9 0.0 1.9 2 0 0 2 2 2 1 MarR family Crp PF00325.20 AIM20433.1 - 0.018 14.7 0.1 0.045 13.4 0.1 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family MarR PF01047.22 AIM20433.1 - 0.019 14.9 0.0 0.042 13.8 0.0 1.6 1 0 0 1 1 1 0 MarR family HTH_31 PF13560.6 AIM20433.1 - 0.03 14.7 1.4 0.14 12.6 0.1 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain HHH_5 PF14520.6 AIM20433.1 - 0.032 14.9 0.0 0.082 13.5 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain HTH_3 PF01381.22 AIM20433.1 - 0.036 14.1 0.0 0.083 13.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix HTH_26 PF13443.6 AIM20433.1 - 0.052 14.0 0.1 0.23 11.9 0.0 2.0 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain HTH_24 PF13412.6 AIM20433.1 - 0.073 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Glyco_transf_7N PF13733.6 AIM20433.1 - 0.11 12.2 0.1 0.3 10.7 0.0 1.8 2 0 0 2 2 2 0 N-terminal region of glycosyl transferase group 7 Glyoxalase_4 PF13669.6 AIM20433.1 - 0.13 12.6 0.0 30 4.9 0.0 2.6 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SBP_bac_3 PF00497.20 AIM20434.1 - 1.6e-46 158.5 0.0 1.9e-46 158.3 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 AIM20434.1 - 0.0059 16.8 0.0 0.24 11.6 0.0 2.3 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site NMT1 PF09084.11 AIM20434.1 - 0.017 15.1 0.1 0.035 14.0 0.1 1.5 1 1 0 1 1 1 0 NMT1/THI5 like BPD_transp_1 PF00528.22 AIM20435.1 - 2.5e-19 69.7 12.7 2.5e-19 69.7 12.7 1.4 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 AIM20436.1 - 2.5e-13 50.2 13.4 2.5e-13 50.2 13.4 1.6 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component Phage_holin_4_1 PF05105.12 AIM20436.1 - 0.5 10.5 3.0 0.29 11.3 0.2 2.1 2 1 0 2 2 2 0 Bacteriophage holin family ABC_tran PF00005.27 AIM20437.1 - 1.2e-36 126.3 0.1 1.7e-36 125.8 0.1 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIM20437.1 - 4.5e-12 46.4 0.1 1.5e-05 25.0 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIM20437.1 - 7e-10 38.7 0.1 1.3e-09 37.8 0.1 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AIM20437.1 - 3.8e-05 23.3 0.1 8.6e-05 22.2 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AIM20437.1 - 9e-05 22.8 0.7 0.00074 19.8 0.7 2.0 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 AIM20437.1 - 0.0001 21.6 0.1 0.0011 18.2 0.1 2.0 1 1 0 1 1 1 1 NB-ARC domain ABC_ATPase PF09818.9 AIM20437.1 - 0.00016 20.6 0.2 0.73 8.6 0.0 2.9 2 1 0 2 2 2 2 Predicted ATPase of the ABC class AAA_23 PF13476.6 AIM20437.1 - 0.0016 19.0 0.0 0.0035 17.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AIM20437.1 - 0.0022 18.4 0.1 0.004 17.6 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 AIM20437.1 - 0.0028 17.4 0.0 0.0077 16.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AIM20437.1 - 0.0055 16.6 0.1 0.012 15.6 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase ATPase PF06745.13 AIM20437.1 - 0.029 13.7 0.2 0.47 9.8 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_15 PF13175.6 AIM20437.1 - 0.035 13.8 0.0 0.059 13.1 0.0 1.4 1 1 1 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.23 AIM20437.1 - 0.038 14.1 0.0 0.072 13.2 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.14 AIM20437.1 - 0.061 13.3 0.3 9.3 6.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 AIM20437.1 - 0.11 12.4 0.1 0.26 11.2 0.1 1.6 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 AIM20437.1 - 0.12 11.9 0.0 2.1 7.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 AIM20437.1 - 0.17 11.9 0.1 0.56 10.3 0.1 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain Aminotran_5 PF00266.19 AIM20438.1 - 2.2e-23 82.8 0.0 1.1e-22 80.5 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 AIM20438.1 - 0.016 14.6 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Peptidase_M20 PF01546.28 AIM20439.1 - 1.4e-25 90.2 0.2 1.8e-25 89.8 0.2 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AIM20439.1 - 7.5e-07 29.0 0.0 1.5e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 AIM20439.1 - 9.4e-07 28.7 0.0 2.3e-06 27.5 0.0 1.6 1 1 1 2 2 2 1 Peptidase family M28 LysE PF01810.18 AIM20440.1 - 2.1e-32 112.2 11.1 2.4e-32 112.0 11.1 1.0 1 0 0 1 1 1 1 LysE type translocator TerC PF03741.16 AIM20440.1 - 0.11 12.1 3.9 0.31 10.7 3.9 1.9 1 1 0 1 1 1 0 Integral membrane protein TerC family CN_hydrolase PF00795.22 AIM20441.1 - 3.8e-30 105.1 0.0 4.2e-30 105.0 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Aminotran_1_2 PF00155.21 AIM20442.1 - 6.1e-57 193.4 0.0 6.9e-57 193.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 AIM20442.1 - 2.1e-07 29.8 0.0 2.9e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 AIM20442.1 - 2.3e-05 23.6 0.0 3.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 AIM20442.1 - 0.00055 19.4 0.1 0.0008 18.8 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aldolase_II PF00596.21 AIM20443.1 - 3.5e-40 137.9 0.0 4e-40 137.7 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Hydrolase PF00702.26 AIM20444.1 - 2.1e-06 28.2 0.0 3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AIM20444.1 - 0.0049 16.9 0.0 0.0097 16.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 AIM20444.1 - 0.011 15.9 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase ARD PF03079.14 AIM20445.1 - 5.1e-33 114.5 0.0 5.7e-33 114.3 0.0 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 AIM20445.1 - 4.4e-05 23.1 0.0 7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Cupin domain SBP_bac_5 PF00496.22 AIM20445.1 - 0.12 11.3 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle IF-2B PF01008.17 AIM20446.1 - 5.4e-66 222.7 0.0 6.5e-66 222.4 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family APH PF01636.23 AIM20447.1 - 3.7e-11 43.4 2.4 3.7e-11 43.4 2.4 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family APH_6_hur PF04655.14 AIM20447.1 - 0.01 15.2 0.0 0.043 13.2 0.0 1.9 2 0 0 2 2 2 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase Urease_gamma PF00547.18 AIM20448.1 - 6.5e-42 141.8 0.3 7.2e-42 141.7 0.3 1.0 1 0 0 1 1 1 1 Urease, gamma subunit Urease_beta PF00699.20 AIM20449.1 - 7.3e-42 141.4 0.0 1.3e-41 140.6 0.0 1.4 1 0 0 1 1 1 1 Urease beta subunit Maff2 PF12750.7 AIM20449.1 - 0.0062 16.3 0.1 0.0089 15.8 0.1 1.2 1 0 0 1 1 1 1 Maff2 family PapD_N PF00345.20 AIM20449.1 - 0.13 12.2 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain Amidohydro_1 PF01979.20 AIM20450.1 - 2.9e-75 253.7 2.2 4.8e-75 253.0 2.2 1.3 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 AIM20450.1 - 3.9e-51 172.4 2.1 8.5e-51 171.3 2.1 1.6 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Amidohydro_3 PF07969.11 AIM20450.1 - 2.8e-08 33.7 6.5 1e-07 31.8 2.2 2.4 1 1 1 2 2 2 2 Amidohydrolase family UreE_N PF02814.15 AIM20451.1 - 8.5e-17 60.5 2.3 1.3e-16 59.9 2.3 1.3 1 0 0 1 1 1 1 UreE urease accessory protein, N-terminal domain UreE_C PF05194.12 AIM20451.1 - 4.7e-11 43.0 0.1 8e-11 42.3 0.1 1.4 1 0 0 1 1 1 1 UreE urease accessory protein, C-terminal domain UreF PF01730.16 AIM20452.1 - 2.7e-21 76.5 3.2 3.7e-21 76.1 3.2 1.2 1 0 0 1 1 1 1 UreF cobW PF02492.19 AIM20453.1 - 3e-30 105.1 0.0 3.9e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 AIM20453.1 - 3.3e-07 29.6 0.3 0.0026 16.8 0.0 2.1 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 AIM20453.1 - 0.0011 18.6 0.2 0.33 10.5 0.0 2.7 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 AIM20453.1 - 0.037 14.6 0.0 0.047 14.2 0.0 1.2 1 0 0 1 1 1 0 ABC transporter MMR_HSR1_Xtn PF16897.5 AIM20453.1 - 0.055 13.5 0.1 0.21 11.6 0.0 1.9 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain AAA_18 PF13238.6 AIM20453.1 - 0.062 13.8 0.0 0.096 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 AIM20453.1 - 0.12 12.1 0.1 0.18 11.5 0.1 1.2 1 0 0 1 1 1 0 Thymidylate kinase RsgA_GTPase PF03193.16 AIM20453.1 - 0.13 12.1 0.0 5.9 6.8 0.0 2.3 2 1 0 2 2 2 0 RsgA GTPase SRP54 PF00448.22 AIM20453.1 - 0.13 11.8 0.0 0.6 9.7 0.0 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain PRK PF00485.18 AIM20453.1 - 0.16 11.7 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family MobB PF03205.14 AIM20453.1 - 0.16 11.9 0.2 0.47 10.4 0.1 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.6 AIM20453.1 - 0.17 12.4 0.1 0.28 11.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 AIM20453.1 - 0.21 11.1 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region UreD PF01774.17 AIM20454.1 - 2.2e-44 151.9 0.0 2.6e-44 151.7 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein UT PF03253.14 AIM20455.1 - 1.7e-89 299.8 31.9 2.1e-89 299.5 31.9 1.0 1 0 0 1 1 1 1 Urea transporter DDDD PF10161.9 AIM20455.1 - 0.95 9.3 2.3 1.8 8.4 0.2 2.4 1 1 0 2 2 2 0 Putative mitochondrial precursor protein Herpes_UL49_5 PF05702.11 AIM20455.1 - 1.5 9.0 4.9 3.4 7.8 1.4 2.9 1 1 0 2 2 2 0 Herpesvirus UL49.5 envelope/tegument protein NicO PF03824.16 AIM20456.1 - 8.1e-91 304.3 20.5 8.1e-91 304.3 20.5 1.3 2 0 0 2 2 2 1 High-affinity nickel-transport protein Tom6 PF17112.5 AIM20456.1 - 0.19 11.3 2.0 3.1 7.4 0.0 2.9 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom6, fungal TMEM18 PF14770.6 AIM20456.1 - 0.57 10.2 7.2 0.61 10.1 0.2 2.7 3 0 0 3 3 3 0 Transmembrane protein 18 HOK_GEF PF01848.16 AIM20457.1 - 1.3e-16 59.7 2.3 1.4e-16 59.6 2.3 1.0 1 0 0 1 1 1 1 Hok/gef family Tmemb_18A PF09771.9 AIM20457.1 - 0.068 13.6 0.1 0.068 13.6 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 188 DUF1974 PF09317.11 AIM20458.1 - 1.1e-118 396.0 0.0 1.4e-118 395.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1974) Acyl-CoA_dh_N PF02771.16 AIM20458.1 - 1.1e-17 64.6 0.0 2.5e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 AIM20458.1 - 1.3e-13 51.5 0.7 2.3e-13 50.6 0.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 AIM20458.1 - 1.2e-08 35.0 0.0 2.4e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain LMBR1 PF04791.16 AIM20458.1 - 1.1 8.1 3.6 1.6 7.6 3.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein SIS_2 PF13580.6 AIM20459.1 - 3.4e-31 108.1 0.1 4.8e-31 107.6 0.1 1.2 1 0 0 1 1 1 1 SIS domain SIS PF01380.22 AIM20459.1 - 1.1e-07 31.8 0.0 1.9e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 SIS domain GATase_4 PF13230.6 AIM20460.1 - 1.7e-114 381.4 0.0 2e-114 381.1 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 AIM20460.1 - 6.8e-05 23.1 0.0 0.00012 22.3 0.0 1.5 1 1 0 1 1 1 1 Glutamine amidotransferase domain YkuD PF03734.14 AIM20461.1 - 3.9e-08 33.8 0.1 1.2e-07 32.2 0.0 1.8 1 1 0 2 2 2 1 L,D-transpeptidase catalytic domain NQRA PF05896.11 AIM20462.1 - 3.3e-113 377.4 0.0 4e-113 377.1 0.0 1.1 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) NQRA_SLBB PF11973.8 AIM20462.1 - 1.3e-22 80.2 0.4 3e-22 79.0 0.4 1.7 1 0 0 1 1 1 1 NQRA C-terminal domain RnfC_N PF13375.6 AIM20462.1 - 4.3e-06 26.6 0.0 8.5e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl_2 PF13533.6 AIM20462.1 - 0.0016 18.2 0.0 0.029 14.2 0.0 2.5 2 0 0 2 2 2 1 Biotin-lipoyl like Peptidase_M23 PF01551.22 AIM20462.1 - 0.07 13.4 0.6 13 6.0 0.1 3.6 3 1 0 3 3 3 0 Peptidase family M23 Apocytochr_F_C PF01333.19 AIM20462.1 - 0.077 13.0 0.0 6.1 6.9 0.0 2.4 1 1 1 2 2 2 0 Apocytochrome F, C-terminal Biotin_lipoyl PF00364.22 AIM20462.1 - 0.081 12.8 0.0 0.21 11.4 0.0 1.6 1 1 0 1 1 1 0 Biotin-requiring enzyme NQR2_RnfD_RnfE PF03116.15 AIM20464.1 - 2.6e-110 368.5 23.3 2.9e-110 368.3 23.3 1.0 1 0 0 1 1 1 1 NQR2, RnfD, RnfE family DUF973 PF06157.11 AIM20464.1 - 0.14 11.2 3.4 0.25 10.3 3.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DUF1427 PF07235.11 AIM20464.1 - 0.55 10.2 4.0 9.5 6.2 0.2 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1427) FMN_bind PF04205.14 AIM20465.1 - 7.8e-16 58.4 0.0 1.4e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 FMN-binding domain Rnf-Nqr PF02508.14 AIM20466.1 - 1.1e-61 207.9 12.3 1.2e-61 207.7 12.3 1.0 1 0 0 1 1 1 1 Rnf-Nqr subunit, membrane protein YrhC PF14143.6 AIM20466.1 - 3.1 8.0 5.8 3 8.0 0.2 2.8 3 0 0 3 3 3 0 YrhC-like protein Rnf-Nqr PF02508.14 AIM20467.1 - 1.5e-59 200.9 18.6 1.7e-59 200.7 18.6 1.0 1 0 0 1 1 1 1 Rnf-Nqr subunit, membrane protein DUF2456 PF10445.9 AIM20467.1 - 2.1 8.5 6.1 2.4 8.3 0.2 2.9 2 2 1 3 3 3 0 Protein of unknown function (DUF2456) NAD_binding_1 PF00175.21 AIM20468.1 - 1.7e-18 67.3 0.0 2.6e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Fer2 PF00111.27 AIM20468.1 - 7.4e-11 41.9 0.4 1.2e-10 41.2 0.4 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain FAD_binding_6 PF00970.24 AIM20468.1 - 2.3e-10 40.7 0.0 7.6e-10 39.0 0.0 1.9 1 1 1 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 AIM20468.1 - 0.0012 19.0 0.0 0.026 14.6 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain ApbE PF02424.15 AIM20469.1 - 7.7e-86 287.8 0.0 9e-86 287.6 0.0 1.0 1 0 0 1 1 1 1 ApbE family NqrM PF04400.13 AIM20470.1 - 5.4e-21 74.1 1.7 7.4e-21 73.6 1.7 1.2 1 0 0 1 1 1 1 (Na+)-NQR maturation NqrM GDPD PF03009.17 AIM20471.1 - 4.8e-18 65.8 0.0 1.9e-17 63.8 0.0 1.8 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family FMN_dh PF01070.18 AIM20471.1 - 0.00094 18.3 0.0 0.002 17.2 0.0 1.8 1 1 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.14 AIM20471.1 - 0.077 12.3 0.0 0.2 11.0 0.0 1.6 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG DUF2880 PF11082.8 AIM20471.1 - 0.13 12.6 0.7 0.3 11.4 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2880) IMS PF00817.20 AIM20472.1 - 2.5e-49 167.1 0.0 4.3e-49 166.4 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 AIM20472.1 - 1.4e-09 38.7 0.1 2.4e-09 37.9 0.1 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 AIM20472.1 - 3.9e-08 33.2 0.0 1.2e-07 31.7 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif Cdd1 PF11731.8 AIM20472.1 - 0.0025 18.0 0.0 0.0054 16.9 0.0 1.5 1 0 0 1 1 1 1 Pathogenicity locus HHH_5 PF14520.6 AIM20472.1 - 0.0037 17.8 0.0 0.014 16.0 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 AIM20472.1 - 0.022 14.6 0.0 0.046 13.5 0.0 1.5 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda HEM4 PF02602.15 AIM20472.1 - 0.033 13.5 0.0 0.062 12.6 0.0 1.4 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD DUF4332 PF14229.6 AIM20472.1 - 0.038 14.2 0.0 0.067 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) HHH PF00633.23 AIM20472.1 - 0.11 12.4 0.1 0.29 11.1 0.1 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif Peptidase_M20 PF01546.28 AIM20473.1 - 7.5e-21 74.8 0.0 1.4e-20 73.9 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AIM20473.1 - 1e-08 35.1 0.0 1.6e-07 31.2 0.1 2.3 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 AIM20473.1 - 0.073 12.7 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 RisS_PPD PF16524.5 AIM20473.1 - 0.1 12.9 0.0 4.2 7.7 0.0 2.9 3 0 0 3 3 3 0 Periplasmic domain of Sensor histidine kinase RisS Pribosyltran PF00156.27 AIM20474.1 - 2.4e-18 66.2 0.0 2.9e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DUF1100 PF06500.11 AIM20475.1 - 1.1e-192 640.4 0.0 1.2e-192 640.2 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_2 PF02230.16 AIM20475.1 - 0.091 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase AXE1 PF05448.12 AIM20475.1 - 0.11 11.2 0.0 0.28 9.8 0.0 1.6 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Crl PF07417.12 AIM20476.1 - 1.6e-54 183.1 0.1 1.8e-54 182.9 0.1 1.0 1 0 0 1 1 1 1 Sigma factor-binding transcriptional regulator Crl AA_kinase PF00696.28 AIM20477.1 - 1.5e-43 149.2 2.8 1.8e-43 148.8 2.8 1.1 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 AIM20477.1 - 1.5e-21 76.1 0.2 4.5e-21 74.6 0.2 1.9 1 0 0 1 1 1 1 PUA domain Aldedh PF00171.22 AIM20478.1 - 1.6e-18 66.5 2.1 5.1e-14 51.7 1.1 2.2 2 0 0 2 2 2 2 Aldehyde dehydrogenase family FlgT_N PF16548.5 AIM20478.1 - 0.018 15.6 4.6 0.54 10.9 0.1 3.1 2 1 0 2 2 2 0 Flagellar assembly protein T, N-terminal domain DUF2007 PF09413.10 AIM20478.1 - 0.064 13.4 0.3 8.2 6.7 0.0 3.4 4 0 0 4 4 4 0 Putative prokaryotic signal transducing protein Esterase PF00756.20 AIM20479.1 - 3.5e-17 62.9 0.0 4.3e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 AIM20479.1 - 7e-05 22.2 0.0 0.00011 21.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 AIM20479.1 - 0.00072 19.1 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 AIM20479.1 - 0.018 14.7 0.0 0.039 13.6 0.0 1.5 1 1 1 2 2 2 0 alpha/beta hydrolase fold TM2 PF05154.16 AIM20480.1 - 2.4e-17 63.0 9.4 3.1e-17 62.6 9.4 1.2 1 0 0 1 1 1 1 TM2 domain ThiI PF02568.14 AIM20481.1 - 0.061 12.9 0.1 0.096 12.3 0.1 1.3 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) DctQ PF04290.12 AIM20483.1 - 0.0027 17.6 3.7 0.0055 16.6 3.7 1.4 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporters, DctQ component RBP_receptor PF14752.6 AIM20485.1 - 0.00068 18.3 0.0 0.00098 17.8 0.0 1.2 1 0 0 1 1 1 1 Retinol binding protein receptor 7TMR-DISM_7TM PF07695.11 AIM20485.1 - 0.024 14.5 7.0 0.62 9.9 0.8 2.4 2 1 0 2 2 2 0 7TM diverse intracellular signalling Ni_hydr_CYTB PF01292.20 AIM20486.1 - 5.2e-20 71.8 14.0 6.2e-20 71.5 14.0 1.1 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 ASFV_L11L PF05293.11 AIM20486.1 - 0.062 13.7 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 African swine fever virus (ASFV) L11L protein SBP_bac_5 PF00496.22 AIM20487.1 - 6.3e-96 321.6 6.0 9.1e-96 321.1 6.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle PD40 PF07676.12 AIM20487.1 - 0.059 13.3 0.1 0.16 12.0 0.1 1.7 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat HxlR PF01638.17 AIM20488.1 - 2.6e-20 72.1 0.1 3.1e-20 71.8 0.1 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix MarR PF01047.22 AIM20488.1 - 0.0017 18.2 0.1 0.0026 17.6 0.1 1.3 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 AIM20488.1 - 0.0033 17.5 0.2 0.006 16.6 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 AIM20488.1 - 0.0036 17.1 0.1 0.0064 16.3 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 AIM20488.1 - 0.041 13.8 0.1 0.086 12.7 0.1 1.5 1 0 0 1 1 1 0 MarR family Rrf2 PF02082.20 AIM20488.1 - 0.12 12.7 0.0 0.19 12.1 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator Flavodoxin_2 PF02525.17 AIM20489.1 - 0.00013 21.8 0.0 0.00013 21.8 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 AIM20489.1 - 0.1 12.4 0.0 0.1 12.4 0.0 1.0 1 0 0 1 1 1 0 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 AIM20490.1 - 1.7e-37 129.1 0.1 2.1e-37 128.7 0.1 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 AIM20490.1 - 1.4e-07 31.4 0.0 2.3e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_4 PF12682.7 AIM20490.1 - 0.14 11.8 0.1 0.25 11.0 0.1 1.4 1 0 0 1 1 1 0 Flavodoxin DSBA PF01323.20 AIM20493.1 - 2.2e-20 73.3 2.8 2.7e-19 69.7 2.8 2.1 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 AIM20493.1 - 2.2e-08 34.4 0.1 3.3e-08 33.9 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin PF00085.20 AIM20493.1 - 1.8e-05 24.6 0.0 0.0041 17.1 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_5 PF13743.6 AIM20493.1 - 0.0078 15.9 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 AIM20493.1 - 0.029 14.8 0.2 0.092 13.2 0.2 1.9 1 1 0 1 1 1 0 Thioredoxin-like domain HTH_18 PF12833.7 AIM20494.1 - 2.3e-23 82.2 2.9 2.7e-23 82.0 0.6 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain AraC_binding_2 PF14525.6 AIM20494.1 - 1.4e-20 73.7 6.0 2.6e-20 72.8 6.0 1.4 1 0 0 1 1 1 1 AraC-binding-like domain HTH_AraC PF00165.23 AIM20494.1 - 2e-13 50.1 0.1 3e-09 36.8 0.0 2.8 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family R2K_2 PF18299.1 AIM20494.1 - 0.14 12.0 0.0 0.37 10.6 0.0 1.6 2 0 0 2 2 2 0 ATP-grasp domain, R2K clade family 2 Aldedh PF00171.22 AIM20495.1 - 2e-166 554.1 0.1 2.3e-166 553.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LysE PF01810.18 AIM20496.1 - 1.1e-47 162.0 14.8 1.3e-47 161.8 14.8 1.0 1 0 0 1 1 1 1 LysE type translocator VitK2_biosynth PF02621.14 AIM20496.1 - 0.069 12.7 0.0 0.093 12.2 0.0 1.1 1 0 0 1 1 1 0 Menaquinone biosynthesis Dyp_perox PF04261.12 AIM20496.1 - 0.23 10.4 0.1 0.39 9.7 0.1 1.3 1 0 0 1 1 1 0 Dyp-type peroxidase family DNA_binding_1 PF01035.20 AIM20497.1 - 2e-33 114.3 1.8 6.9e-32 109.4 0.4 2.5 2 0 0 2 2 2 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Ada_Zn_binding PF02805.16 AIM20497.1 - 3.3e-32 110.3 3.4 4.2e-32 110.0 1.7 2.0 2 0 0 2 2 2 1 Metal binding domain of Ada HTH_18 PF12833.7 AIM20497.1 - 7.4e-17 61.4 0.7 7.4e-17 61.4 0.7 2.2 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_AraC PF00165.23 AIM20497.1 - 8.5e-13 48.0 0.0 5.3e-08 32.8 0.0 2.7 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Methyltransf_1N PF02870.15 AIM20497.1 - 0.098 13.5 0.0 0.19 12.5 0.0 1.5 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain Oxygenase-NA PF09859.9 AIM20498.1 - 4.4e-87 290.0 0.1 5.4e-87 289.7 0.1 1.1 1 0 0 1 1 1 1 Oxygenase, catalysing oxidative methylation of damaged DNA 2OG-FeII_Oxy_3 PF13640.6 AIM20498.1 - 8.7e-06 26.5 0.0 1.3e-05 26.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 AIM20498.1 - 0.035 14.8 0.0 0.063 13.9 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily TehB PF03848.14 AIM20499.1 - 4e-94 313.5 0.0 5e-94 313.2 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB DUF1971 PF09313.11 AIM20499.1 - 2.4e-28 98.0 0.1 4.2e-28 97.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1971) Methyltransf_25 PF13649.6 AIM20499.1 - 2.3e-08 34.7 0.0 4e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AIM20499.1 - 1.9e-07 31.0 0.0 2.5e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AIM20499.1 - 7.6e-07 29.7 0.0 1.3e-06 29.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIM20499.1 - 6.2e-05 23.7 0.0 9.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AIM20499.1 - 0.00057 19.7 0.0 0.00091 19.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AIM20499.1 - 0.0019 17.8 0.0 0.0028 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 AIM20499.1 - 0.042 13.5 0.0 0.064 12.9 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) DUF1615 PF07759.12 AIM20500.1 - 1.8e-145 484.1 0.0 2.1e-145 483.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1615) Tricorn_C1 PF14684.6 AIM20500.1 - 0.13 12.4 0.1 0.32 11.1 0.1 1.7 1 1 0 1 1 1 0 Tricorn protease C1 domain TPP_enzyme_N PF02776.18 AIM20501.1 - 1.5e-34 119.0 0.1 3.7e-34 117.8 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 AIM20501.1 - 1.7e-18 66.6 0.0 3.9e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 AIM20501.1 - 1.8e-17 63.6 0.2 1.1e-16 61.0 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PagP PF07017.11 AIM20502.1 - 5.6e-68 226.9 1.4 6.6e-68 226.7 1.4 1.1 1 0 0 1 1 1 1 Antimicrobial peptide resistance and lipid A acylation protein PagP DUF2501 PF10696.9 AIM20503.1 - 2.1e-29 101.6 8.1 2.1e-29 101.6 8.1 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF2501) DUF333 PF03891.15 AIM20504.1 - 2.5e-20 72.4 0.1 3.1e-20 72.1 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF333) Zip PF02535.22 AIM20506.1 - 1.6e-09 37.5 32.7 5.3e-06 25.9 3.3 2.5 2 1 0 2 2 2 2 ZIP Zinc transporter DeoRC PF00455.22 AIM20507.1 - 1.7e-38 132.1 0.0 2.3e-38 131.6 0.0 1.2 1 0 0 1 1 1 1 DeoR C terminal sensor domain HTH_DeoR PF08220.12 AIM20507.1 - 7.8e-16 57.6 0.3 1.3e-15 56.9 0.3 1.4 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 AIM20507.1 - 4.4e-05 23.3 0.4 7.2e-05 22.6 0.4 1.3 1 0 0 1 1 1 1 HTH domain Put_DNA-bind_N PF06971.13 AIM20507.1 - 0.0024 17.8 0.1 0.0051 16.8 0.1 1.4 1 0 0 1 1 1 1 Putative DNA-binding protein N-terminus HTH_24 PF13412.6 AIM20507.1 - 0.01 15.4 0.7 0.018 14.6 0.7 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 AIM20507.1 - 0.013 15.6 0.7 0.027 14.5 0.7 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain MarR PF01047.22 AIM20507.1 - 0.015 15.2 0.6 0.027 14.4 0.6 1.4 1 0 0 1 1 1 0 MarR family HTH_38 PF13936.6 AIM20507.1 - 0.089 12.6 0.3 0.16 11.7 0.3 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_AsnC-type PF13404.6 AIM20507.1 - 0.29 11.0 4.3 0.25 11.2 2.6 1.8 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Glyoxalase PF00903.25 AIM20508.1 - 4.3e-11 43.1 0.0 5.1e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 AIM20508.1 - 1.5e-05 25.2 0.0 1.9e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 AIM20508.1 - 1.6e-05 25.6 0.2 2.2e-05 25.2 0.2 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain LysR_substrate PF03466.20 AIM20509.1 - 3.4e-38 131.1 6.6 4.6e-38 130.7 6.6 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM20509.1 - 9.2e-15 54.3 0.1 1.9e-14 53.3 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family Pirin PF02678.16 AIM20510.1 - 2.5e-33 114.3 0.2 4.2e-33 113.6 0.2 1.4 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 AIM20510.1 - 8e-30 103.3 0.1 2.9e-29 101.5 0.0 1.8 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Pirin_C_2 PF17954.1 AIM20510.1 - 0.0023 18.0 0.0 0.0049 17.0 0.0 1.5 1 0 0 1 1 1 1 Quercetinase C-terminal cupin domain Isochorismatase PF00857.20 AIM20511.1 - 3.3e-23 82.8 0.0 7.7e-23 81.6 0.0 1.6 1 1 0 1 1 1 1 Isochorismatase family HSDR_N PF04313.14 AIM20512.1 - 3.5e-12 46.7 0.1 5.7e-08 32.9 0.0 2.9 2 1 1 3 3 3 2 Type I restriction enzyme R protein N terminus (HSDR_N) HSDR_N_2 PF13588.6 AIM20512.1 - 1.8e-09 37.6 0.0 3.6e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) DUF393 PF04134.12 AIM20514.1 - 1.4e-29 103.7 1.0 1.6e-29 103.5 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF393 Cytochrom_B_C PF00032.17 AIM20515.1 - 0.007 16.6 0.6 0.012 15.9 0.6 1.4 1 1 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD EcsB PF05975.12 AIM20515.1 - 0.012 14.5 0.1 0.014 14.3 0.1 1.0 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB FHIPEP PF00771.20 AIM20515.1 - 0.03 12.8 0.0 0.032 12.7 0.0 1.0 1 0 0 1 1 1 0 FHIPEP family CPBP PF02517.16 AIM20515.1 - 0.061 13.7 0.0 0.064 13.6 0.0 1.1 1 0 0 1 1 1 0 CPBP intramembrane metalloprotease Acetyltransf_3 PF13302.7 AIM20516.1 - 3.2e-28 99.1 0.1 3.8e-28 98.9 0.1 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AIM20516.1 - 8.4e-06 26.0 0.0 9.9e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 AIM20516.1 - 0.012 15.6 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein DUF2076 PF09849.9 AIM20517.1 - 3.9e-71 240.2 23.3 4.4e-71 240.0 23.3 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) TauE PF01925.19 AIM20517.1 - 0.0074 16.0 0.1 0.13 11.9 0.0 2.0 2 0 0 2 2 2 1 Sulfite exporter TauE/SafE Muted PF14942.6 AIM20517.1 - 0.037 14.4 0.7 0.072 13.4 0.7 1.3 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein RTBV_P12 PF06361.11 AIM20517.1 - 0.042 14.3 0.0 0.069 13.6 0.0 1.4 1 0 0 1 1 1 0 Rice tungro bacilliform virus P12 protein SARAF PF06682.12 AIM20517.1 - 0.072 12.7 5.2 0.1 12.2 5.2 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DMPK_coil PF08826.10 AIM20517.1 - 0.1 12.7 3.9 0.82 9.8 1.1 2.3 2 0 0 2 2 2 0 DMPK coiled coil domain like DUF4407 PF14362.6 AIM20517.1 - 0.37 10.1 5.8 0.49 9.7 5.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 AIM20517.1 - 3.8 7.4 7.3 1.2 9.0 3.1 2.2 2 1 0 2 2 2 0 Septum formation initiator Nnf1 PF03980.14 AIM20517.1 - 9.5 6.7 10.9 1 9.8 5.8 2.0 2 1 0 2 2 2 0 Nnf1 MLTR_LBD PF17765.1 AIM20518.1 - 1.2e-31 110.2 7.3 1.6e-31 109.7 7.3 1.2 1 0 0 1 1 1 1 MmyB-like transcription regulator ligand binding domain HTH_31 PF13560.6 AIM20518.1 - 8.9e-19 67.6 1.2 2.6e-18 66.1 1.2 1.8 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 AIM20518.1 - 1.8e-05 24.7 0.1 3.4e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix PAS PF00989.25 AIM20518.1 - 0.047 13.7 0.0 0.11 12.5 0.0 1.7 1 1 0 1 1 1 0 PAS fold HTH_26 PF13443.6 AIM20518.1 - 0.083 13.3 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain TetR_C_16 PF17920.1 AIM20518.1 - 0.18 12.1 1.8 0.46 10.7 0.2 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Methyltransf_11 PF08241.12 AIM20519.1 - 3.7e-27 94.8 0.1 9.4e-27 93.5 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AIM20519.1 - 5.9e-25 87.8 0.1 1.4e-24 86.6 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AIM20519.1 - 1.2e-21 77.1 0.0 1.8e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AIM20519.1 - 5.7e-20 71.6 0.0 7.9e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 AIM20519.1 - 5.2e-19 68.7 0.0 7.3e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIM20519.1 - 8.2e-18 65.0 0.0 1.6e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AIM20519.1 - 2.4e-08 33.7 0.0 3.5e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 AIM20519.1 - 4.8e-07 29.6 0.0 8.1e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_29 PF03141.16 AIM20519.1 - 6.4e-07 28.3 0.0 8.7e-07 27.8 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_9 PF08003.11 AIM20519.1 - 1.1e-05 24.5 0.0 1.6e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) TehB PF03848.14 AIM20519.1 - 1.4e-05 24.6 0.0 2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_8 PF05148.15 AIM20519.1 - 1.8e-05 24.7 0.0 0.00017 21.6 0.0 2.0 1 1 0 1 1 1 1 Hypothetical methyltransferase CMAS PF02353.20 AIM20519.1 - 3.5e-05 23.2 0.0 5.5e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 AIM20519.1 - 0.00012 21.6 0.0 0.00016 21.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DREV PF05219.12 AIM20519.1 - 0.00049 19.3 0.0 0.00069 18.8 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_32 PF13679.6 AIM20519.1 - 0.003 17.6 0.1 0.0055 16.7 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain SIS_2 PF13580.6 AIM20519.1 - 0.014 15.4 0.7 0.026 14.6 0.7 1.4 1 0 0 1 1 1 0 SIS domain tRNA_U5-meth_tr PF05958.11 AIM20519.1 - 0.014 14.4 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_24 PF13578.6 AIM20519.1 - 0.047 14.7 0.4 0.12 13.4 0.2 1.9 2 1 0 2 2 1 0 Methyltransferase domain TPMT PF05724.11 AIM20519.1 - 0.074 12.7 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_4 PF02390.17 AIM20519.1 - 0.18 11.3 0.0 0.4 10.1 0.0 1.6 1 1 0 1 1 1 0 Putative methyltransferase MIP PF00230.20 AIM20520.1 - 1e-52 179.1 19.1 1.2e-52 178.9 19.1 1.0 1 0 0 1 1 1 1 Major intrinsic protein Phytase-like PF13449.6 AIM20521.1 - 1.7e-51 175.8 0.2 2.1e-51 175.5 0.2 1.1 1 0 0 1 1 1 1 Esterase-like activity of phytase LtrA PF06772.11 AIM20522.1 - 2.1e-105 352.9 39.1 2.3e-105 352.7 39.1 1.0 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) Phage_holin_3_5 PF16085.5 AIM20522.1 - 0.014 15.5 0.3 0.06 13.5 0.2 2.2 1 1 0 1 1 1 0 Bacteriophage holin Hol, superfamily III MFS_MOT1 PF16983.5 AIM20522.1 - 1.4 9.4 9.9 0.044 14.2 2.1 2.6 3 0 0 3 3 3 0 Molybdate transporter of MFS superfamily DUF1471 PF07338.13 AIM20523.1 - 6.8e-20 70.8 0.0 1.1e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1471) RrnaAD PF00398.20 AIM20524.1 - 6.8e-05 22.1 0.0 9.7e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.12 AIM20524.1 - 0.051 14.3 0.0 0.077 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 AIM20524.1 - 0.096 12.5 0.0 0.21 11.4 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Acetyltransf_1 PF00583.25 AIM20525.1 - 1.7e-10 41.2 0.0 2.1e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AIM20525.1 - 3.2e-09 36.8 0.0 3.9e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AIM20525.1 - 5.4e-08 33.0 0.0 6.6e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AIM20525.1 - 8.7e-08 32.5 0.0 1.2e-07 32.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AIM20525.1 - 0.0003 20.7 0.0 0.00046 20.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 AIM20525.1 - 0.0012 19.5 0.0 0.0014 19.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AIM20525.1 - 0.0025 17.9 0.0 0.0039 17.3 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 AIM20525.1 - 0.003 17.5 0.0 0.022 14.7 0.0 2.2 1 1 1 2 2 2 1 ESCO1/2 acetyl-transferase Peripla_BP_2 PF01497.18 AIM20526.1 - 6e-27 94.7 0.0 9.4e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein Glu_cys_ligase PF04262.14 AIM20526.1 - 0.074 11.7 0.0 0.1 11.2 0.0 1.1 1 0 0 1 1 1 0 Glutamate-cysteine ligase TonB_dep_Rec PF00593.24 AIM20527.1 - 4.4e-59 201.6 25.3 6.1e-59 201.1 25.3 1.3 1 0 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AIM20527.1 - 1.1e-17 64.6 1.5 2.9e-17 63.2 1.5 1.8 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain DUF560 PF04575.13 AIM20527.1 - 0.0021 17.5 0.8 0.079 12.4 0.5 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF560) S_tail_recep_bd PF14928.6 AIM20527.1 - 0.0044 17.6 0.1 0.014 16.0 0.1 1.9 1 0 0 1 1 1 1 Short tail fibre protein receptor-binding domain Acetyltransf_10 PF13673.7 AIM20528.1 - 8.8e-13 48.3 0.0 1.4e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AIM20528.1 - 6.1e-12 45.8 0.1 8e-12 45.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AIM20528.1 - 3.5e-09 37.0 0.0 6.5e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 AIM20528.1 - 0.0035 17.1 0.1 0.0046 16.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_CG PF14542.6 AIM20528.1 - 0.0044 17.1 0.0 0.0076 16.4 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 AIM20528.1 - 0.012 15.7 0.0 0.017 15.3 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 AIM20528.1 - 0.1 12.6 0.0 0.24 11.4 0.0 1.7 2 0 0 2 2 2 0 FR47-like protein SKI PF01202.22 AIM20529.1 - 1.3e-45 155.4 0.0 1.4e-45 155.2 0.0 1.0 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 AIM20529.1 - 1.1e-06 28.9 0.2 1.6e-05 25.1 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AIM20529.1 - 7.5e-06 26.5 0.0 4.3e-05 24.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 AIM20529.1 - 2.8e-05 24.3 0.1 7.6e-05 22.9 0.1 1.8 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_17 PF13207.6 AIM20529.1 - 0.0035 17.8 0.1 0.038 14.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 AIM20529.1 - 0.0064 16.3 0.1 0.012 15.4 0.1 1.4 1 1 0 1 1 1 1 Cytidylate kinase AAA_28 PF13521.6 AIM20529.1 - 0.0089 16.3 0.2 0.029 14.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 AIM20529.1 - 0.059 13.8 0.0 0.12 12.8 0.0 1.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ADK PF00406.22 AIM20529.1 - 0.095 12.8 0.1 18 5.4 0.0 2.2 2 0 0 2 2 2 0 Adenylate kinase AAA_25 PF13481.6 AIM20529.1 - 0.3 10.6 2.3 0.86 9.1 1.3 2.0 1 1 1 2 2 2 0 AAA domain HTH_18 PF12833.7 AIM20530.1 - 5e-19 68.3 0.4 5e-19 68.3 0.4 2.1 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_AraC PF00165.23 AIM20530.1 - 1.6e-12 47.2 0.0 5e-06 26.5 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family AraC_binding PF02311.19 AIM20530.1 - 7.4e-09 35.6 3.7 4.3e-08 33.1 3.7 2.2 1 1 0 1 1 1 1 AraC-like ligand binding domain Cupin_2 PF07883.11 AIM20530.1 - 0.0008 19.1 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 Cupin domain HTH_28 PF13518.6 AIM20530.1 - 0.0091 16.1 0.7 0.11 12.6 0.2 2.6 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 AIM20530.1 - 0.013 15.2 0.1 0.17 11.7 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Crp_2 PF13545.6 AIM20530.1 - 0.047 13.7 0.2 0.34 10.9 0.2 2.3 1 1 0 1 1 1 0 Crp-like helix-turn-helix domain SnoaL_2 PF12680.7 AIM20531.1 - 3.8e-06 27.5 0.1 4.7e-06 27.2 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain LEH PF07858.12 AIM20531.1 - 0.00068 19.7 0.1 0.00082 19.5 0.1 1.1 1 0 0 1 1 1 1 Limonene-1,2-epoxide hydrolase catalytic domain YaiA PF16362.5 AIM20532.1 - 5.9e-21 74.3 0.2 6.9e-21 74.1 0.2 1.0 1 0 0 1 1 1 1 YaiA protein Ppnp PF06865.11 AIM20533.1 - 3.4e-32 110.7 0.0 3.7e-32 110.6 0.0 1.0 1 0 0 1 1 1 1 Pyrimidine/purine nucleoside phosphorylase RdgC PF04381.12 AIM20534.1 - 1.6e-128 428.2 3.8 1.8e-128 428.0 3.8 1.0 1 0 0 1 1 1 1 Putative exonuclease, RdgC ROK PF00480.20 AIM20535.1 - 7e-87 291.6 0.1 8e-87 291.4 0.1 1.0 1 0 0 1 1 1 1 ROK family Glucokinase PF02685.16 AIM20535.1 - 1e-09 37.9 0.3 2.2e-09 36.8 0.3 1.6 1 1 0 1 1 1 1 Glucokinase BcrAD_BadFG PF01869.20 AIM20535.1 - 0.00063 19.3 0.0 0.14 11.6 0.0 2.2 2 1 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family Hydant_A_N PF05378.13 AIM20535.1 - 0.03 14.0 0.1 0.059 13.1 0.1 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region DEDD_Tnp_IS110 PF01548.17 AIM20535.1 - 0.048 13.5 0.0 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 Transposase PhdYeFM_antitox PF02604.19 AIM20536.1 - 2.9e-08 33.4 0.1 3.8e-08 33.0 0.1 1.2 1 0 0 1 1 1 1 Antitoxin Phd_YefM, type II toxin-antitoxin system DUF4851 PF16143.5 AIM20536.1 - 0.11 11.9 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4851) DUF2375 PF09558.10 AIM20536.1 - 0.16 12.0 0.0 0.66 10.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2375) PHD_like PF12910.7 AIM20536.1 - 0.22 11.6 0.0 0.25 11.3 0.0 1.1 1 0 0 1 1 1 0 Antitoxin of toxin-antitoxin, RelE / RelB, TA system PIN PF01850.21 AIM20537.1 - 1.4e-12 48.2 0.0 1.6e-12 48.0 0.0 1.0 1 0 0 1 1 1 1 PIN domain PRD PF00874.20 AIM20538.1 - 1.5e-43 147.0 7.2 2e-21 76.1 0.0 2.7 3 0 0 3 3 3 2 PRD domain CAT_RBD PF03123.15 AIM20538.1 - 3.8e-23 81.2 1.1 7.8e-23 80.2 1.1 1.6 1 0 0 1 1 1 1 CAT RNA binding domain MRP-S24 PF14955.6 AIM20538.1 - 0.083 12.9 0.6 0.18 11.8 0.1 1.7 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S24 AAA_23 PF13476.6 AIM20539.1 - 4.2e-25 89.4 8.8 4.2e-25 89.4 8.8 6.9 1 1 5 6 6 1 1 AAA domain SbcCD_C PF13558.6 AIM20539.1 - 1.3e-15 57.4 4.3 5.8e-15 55.3 0.7 3.4 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 AIM20539.1 - 1.2e-10 41.2 0.0 4e-05 23.1 0.0 2.7 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AIM20539.1 - 8.2e-07 28.7 0.0 1.9e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 AIM20539.1 - 0.0025 18.3 0.0 0.0025 18.3 0.0 7.5 2 1 1 3 3 1 1 ABC transporter AAA_21 PF13304.6 AIM20539.1 - 0.0028 17.5 0.0 0.0072 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 AIM20539.1 - 0.0049 16.5 0.0 0.026 14.1 0.0 2.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 AIM20539.1 - 0.045 13.7 0.4 0.15 11.9 0.0 2.2 2 0 0 2 2 2 0 NTPase TsaE PF02367.17 AIM20539.1 - 0.067 13.2 0.0 0.22 11.5 0.0 1.9 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 AIM20539.1 - 0.084 13.1 0.0 0.084 13.1 0.0 6.3 4 2 2 6 6 5 0 AAA domain MMR_HSR1 PF01926.23 AIM20539.1 - 0.21 11.7 1.2 0.96 9.6 0.0 2.9 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_25 PF13481.6 AIM20539.1 - 0.26 10.8 0.0 0.26 10.8 0.0 4.1 3 1 1 4 4 4 0 AAA domain RsgA_GTPase PF03193.16 AIM20539.1 - 0.61 10.0 0.0 0.61 10.0 0.0 3.8 5 0 0 5 5 4 0 RsgA GTPase GTP_EFTU PF00009.27 AIM20539.1 - 1.8 8.1 0.0 1.8 8.1 0.0 4.1 4 2 0 4 4 3 0 Elongation factor Tu GTP binding domain SbcD_C PF12320.8 AIM20540.1 - 5.7e-24 84.2 5.5 5.7e-24 84.2 5.5 1.9 2 0 0 2 2 2 1 Type 5 capsule protein repressor C-terminal domain Metallophos PF00149.28 AIM20540.1 - 3.4e-13 50.5 0.0 9.4e-13 49.1 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AIM20540.1 - 2.2e-09 37.7 0.0 6.3e-08 33.0 0.0 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain YdjC PF04794.12 AIM20540.1 - 0.048 13.6 0.5 0.081 12.9 0.5 1.3 1 0 0 1 1 1 0 YdjC-like protein Metallophos_3 PF14582.6 AIM20540.1 - 0.085 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily Trans_reg_C PF00486.28 AIM20541.1 - 1.3e-28 98.9 0.0 2.3e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Response_reg PF00072.24 AIM20541.1 - 1e-27 96.5 0.0 1.6e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Peripla_BP_5 PF13433.6 AIM20541.1 - 0.14 11.1 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein domain PhoR PF11808.8 AIM20542.1 - 4.3e-30 104.0 9.9 1.1e-29 102.7 9.9 1.7 1 0 0 1 1 1 1 Phosphate regulon sensor protein PhoR HATPase_c PF02518.26 AIM20542.1 - 7.1e-26 90.9 0.0 1.3e-25 90.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AIM20542.1 - 4.8e-19 68.1 0.9 1.3e-18 66.8 0.2 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 AIM20542.1 - 7.9e-08 32.3 0.1 2e-07 31.0 0.0 1.8 2 0 0 2 2 2 1 PAS fold HATPase_c_2 PF13581.6 AIM20542.1 - 5.4e-07 29.6 0.0 9.2e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 AIM20542.1 - 4e-05 23.5 0.0 7.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.7 AIM20542.1 - 0.00086 19.3 0.0 0.0024 17.9 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 AIM20542.1 - 0.031 14.5 0.0 0.082 13.2 0.0 1.8 2 0 0 2 2 2 0 PAS domain KAAG1 PF15354.6 AIM20542.1 - 0.2 12.2 0.4 2 9.0 0.1 2.3 1 1 1 2 2 2 0 Kidney-associated antigen 1 DUF1282 PF06930.12 AIM20542.1 - 0.23 11.2 1.5 0.4 10.4 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) PBP_like_2 PF12849.7 AIM20543.1 - 2.5e-28 99.5 0.0 5.1e-28 98.6 0.0 1.4 1 1 0 1 1 1 1 PBP superfamily domain PBP_like PF12727.7 AIM20543.1 - 4.3e-10 39.0 0.0 5.9e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 PBP superfamily domain SBP_bac_11 PF13531.6 AIM20543.1 - 1.7e-06 27.9 1.6 1.2e-05 25.1 1.6 2.0 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein LysR_substrate PF03466.20 AIM20543.1 - 0.00089 18.7 0.7 0.0031 16.9 0.1 2.1 2 1 0 2 2 2 1 LysR substrate binding domain Branch_AA_trans PF05525.13 AIM20544.1 - 1.2e-151 505.5 34.6 1.4e-151 505.3 34.6 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport protein AA_permease PF00324.21 AIM20545.1 - 4.6e-110 368.5 54.1 5.2e-110 368.3 54.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 AIM20545.1 - 4.7e-44 150.9 58.8 5.5e-44 150.7 58.8 1.0 1 0 0 1 1 1 1 Amino acid permease Spore_permease PF03845.13 AIM20545.1 - 2e-06 26.9 19.8 2e-06 26.9 19.8 3.5 2 2 1 3 3 3 1 Spore germination protein HTH_3 PF01381.22 AIM20546.1 - 9.6e-11 41.6 0.1 1.5e-10 41.0 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix YdaS_antitoxin PF15943.5 AIM20546.1 - 1.5e-05 24.8 0.0 2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_31 PF13560.6 AIM20546.1 - 0.00034 20.9 0.0 0.00053 20.3 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 AIM20546.1 - 0.00087 19.3 0.0 0.0012 18.9 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.6 AIM20546.1 - 0.0024 17.6 0.0 0.0044 16.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AIM20546.1 - 0.0086 15.9 0.0 0.026 14.3 0.0 1.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_26 PF13443.6 AIM20546.1 - 0.0095 16.4 0.2 0.034 14.6 0.0 1.8 2 0 0 2 2 2 1 Cro/C1-type HTH DNA-binding domain HTH_37 PF13744.6 AIM20546.1 - 0.022 14.7 0.0 0.059 13.3 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain MarR_2 PF12802.7 AIM20546.1 - 0.029 14.3 0.0 0.041 13.8 0.0 1.2 1 0 0 1 1 1 0 MarR family HTH_IclR PF09339.10 AIM20546.1 - 0.037 13.8 0.1 0.053 13.3 0.1 1.2 1 0 0 1 1 1 0 IclR helix-turn-helix domain Mg_chelatase_C PF13335.6 AIM20546.1 - 0.039 14.6 0.0 0.079 13.6 0.0 1.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal CENP-B_N PF04218.13 AIM20546.1 - 0.058 13.0 0.0 0.093 12.4 0.0 1.3 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain Fe_dep_repress PF01325.19 AIM20546.1 - 0.059 13.6 0.1 0.19 11.9 0.1 1.9 1 1 1 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain Sigma54_DBD PF04552.13 AIM20546.1 - 0.083 12.6 0.0 0.095 12.4 0.0 1.1 1 0 0 1 1 1 0 Sigma-54, DNA binding domain HTH_AsnC-type PF13404.6 AIM20546.1 - 0.1 12.4 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HigB-like_toxin PF05015.13 AIM20547.1 - 7.9e-20 71.1 0.0 8.8e-20 70.9 0.0 1.0 1 0 0 1 1 1 1 RelE-like toxin of type II toxin-antitoxin system HigB MS_channel PF00924.18 AIM20549.1 - 4.6e-57 192.9 0.1 8.6e-56 188.7 0.1 2.5 1 1 0 1 1 1 1 Mechanosensitive ion channel SATase_N PF06426.14 AIM20549.1 - 0.11 12.9 0.1 0.23 11.9 0.1 1.5 1 0 0 1 1 1 0 Serine acetyltransferase, N-terminal ELO PF01151.18 AIM20549.1 - 0.63 9.5 5.5 2.5 7.5 0.2 2.1 1 1 1 2 2 2 0 GNS1/SUR4 family DUF3267 PF11667.8 AIM20549.1 - 4.1 7.7 8.3 0.68 10.2 0.6 2.4 2 0 0 2 2 2 0 Putative zincin peptidase Alpha-amylase PF00128.24 AIM20550.1 - 6e-77 259.5 0.0 8.4e-77 259.0 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_N PF02903.14 AIM20550.1 - 1.4e-12 47.8 0.0 2.7e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Alpha amylase, N-terminal ig-like domain Malt_amylase_C PF16657.5 AIM20550.1 - 0.019 15.1 0.0 0.039 14.1 0.0 1.5 1 0 0 1 1 1 0 Maltogenic Amylase, C-terminal domain G_glu_transpept PF01019.21 AIM20551.1 - 3e-181 603.7 0.3 3.4e-181 603.5 0.3 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase AhpC-TSA PF00578.21 AIM20552.1 - 2e-35 121.4 0.0 3e-35 120.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AIM20552.1 - 3.4e-20 72.3 0.0 4.1e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 AIM20552.1 - 3.7e-11 42.7 0.0 6.9e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Thioredoxin_8 PF13905.6 AIM20552.1 - 0.089 13.1 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like ACP_PD PF04336.12 AIM20553.1 - 1.7e-33 115.1 3.7 2.6e-33 114.6 3.7 1.2 1 0 0 1 1 1 1 Acyl carrier protein phosphodiesterase Queuosine_synth PF02547.15 AIM20554.1 - 1.2e-131 438.7 0.0 1.3e-131 438.6 0.0 1.0 1 0 0 1 1 1 1 Queuosine biosynthesis protein TGT PF01702.18 AIM20555.1 - 1.9e-154 514.0 0.0 2.3e-154 513.8 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase YajC PF02699.15 AIM20556.1 - 8.6e-26 89.6 0.8 1e-25 89.4 0.8 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Orf78 PF06024.12 AIM20556.1 - 0.0041 17.4 0.1 0.0066 16.7 0.1 1.3 1 0 0 1 1 1 1 Orf78 (ac78) MreC PF04085.14 AIM20556.1 - 0.086 12.7 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 rod shape-determining protein MreC DUF4131 PF13567.6 AIM20556.1 - 0.13 11.9 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF5385 PF17359.2 AIM20556.1 - 0.17 11.4 0.0 0.21 11.1 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5385) SecD-TM1 PF13721.6 AIM20557.1 - 9.3e-43 144.9 4.5 4.6e-37 126.6 0.0 3.6 4 1 0 4 4 4 2 SecD export protein N-terminal TM region SecD_SecF PF02355.16 AIM20557.1 - 9.5e-17 61.0 10.7 1.7e-16 60.2 10.7 1.3 1 0 0 1 1 1 1 Protein export membrane protein MMPL PF03176.15 AIM20557.1 - 1.4e-09 37.3 15.0 3.3e-09 36.1 15.0 1.6 1 0 0 1 1 1 1 MMPL family Sec_GG PF07549.14 AIM20557.1 - 1.8e-06 27.2 0.0 4.2e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 SecD/SecF GG Motif HeH PF12949.7 AIM20557.1 - 0.18 11.5 0.0 0.75 9.6 0.0 2.1 2 0 0 2 2 2 0 HeH/LEM domain SecD_SecF PF02355.16 AIM20558.1 - 4.9e-72 241.3 12.8 7.2e-72 240.8 12.8 1.2 1 0 0 1 1 1 1 Protein export membrane protein Sec_GG PF07549.14 AIM20558.1 - 7.5e-11 41.2 0.0 2e-10 39.8 0.0 1.8 1 0 0 1 1 1 1 SecD/SecF GG Motif ACR_tran PF00873.19 AIM20558.1 - 0.0001 20.2 9.7 0.00014 19.7 9.7 1.1 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family DUF3251 PF11622.8 AIM20559.1 - 9.1e-49 165.3 1.3 1.1e-48 165.0 1.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3251) LPP PF04728.13 AIM20559.1 - 0.084 13.3 3.6 1.7 9.1 1.1 2.4 2 0 0 2 2 2 0 Lipoprotein leucine-zipper ZapB PF06005.12 AIM20559.1 - 0.17 12.3 1.4 0.43 11.1 1.4 1.7 1 1 0 1 1 1 0 Cell division protein ZapB ATP-cone PF03477.16 AIM20560.1 - 6.2e-16 58.7 0.1 9.1e-16 58.2 0.1 1.3 1 0 0 1 1 1 1 ATP cone domain RibD_C PF01872.17 AIM20561.1 - 9e-57 192.1 0.0 1.2e-56 191.7 0.0 1.2 1 0 0 1 1 1 1 RibD C-terminal domain dCMP_cyt_deam_1 PF00383.23 AIM20561.1 - 1.6e-20 72.9 0.0 2.5e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 AIM20561.1 - 9.8e-12 44.8 0.0 1.4e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase Inv-AAD PF18785.1 AIM20561.1 - 0.002 18.0 0.0 0.019 14.8 0.0 2.1 1 1 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase APOBEC_N PF08210.11 AIM20561.1 - 0.038 13.9 0.0 0.067 13.1 0.0 1.3 1 0 0 1 1 1 0 APOBEC-like N-terminal domain DMRL_synthase PF00885.19 AIM20562.1 - 3.3e-55 185.8 1.6 3.8e-55 185.6 1.6 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase NusB PF01029.18 AIM20563.1 - 2.7e-37 128.0 0.2 3.1e-37 127.8 0.2 1.0 1 0 0 1 1 1 1 NusB family Imm3 PF14425.6 AIM20563.1 - 0.014 15.4 0.1 0.059 13.4 0.0 1.8 2 0 0 2 2 2 0 Immunity protein Imm3 AIRS PF00586.24 AIM20564.1 - 1.1e-22 80.4 0.0 3e-22 79.1 0.0 1.7 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain AIRS_C PF02769.22 AIM20564.1 - 2.9e-08 34.0 0.0 4e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain PgpA PF04608.13 AIM20565.1 - 3.8e-52 176.1 7.5 4.4e-52 175.9 7.5 1.0 1 0 0 1 1 1 1 Phosphatidylglycerophosphatase A DUF4281 PF14108.6 AIM20565.1 - 0.14 12.6 6.2 0.19 12.1 1.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4281) TfoX_N PF04993.13 AIM20565.1 - 0.18 12.1 0.2 0.3 11.3 0.2 1.3 1 0 0 1 1 1 0 TfoX N-terminal domain Aldo_ket_red PF00248.21 AIM20566.1 - 1.7e-78 263.8 0.0 2.2e-78 263.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DXP_synthase_N PF13292.6 AIM20567.1 - 2.6e-118 394.1 0.0 7.8e-118 392.6 0.0 1.7 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.24 AIM20567.1 - 4.5e-38 130.7 0.0 7.8e-38 129.9 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 AIM20567.1 - 4.9e-27 94.3 0.0 9.5e-27 93.3 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.21 AIM20567.1 - 6.2e-06 26.1 0.9 5.1e-05 23.1 0.2 2.6 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 AIM20567.1 - 1.7e-05 23.9 0.3 2.9e-05 23.2 0.3 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_N PF00456.21 AIM20567.1 - 0.00041 19.4 0.0 0.0095 14.9 0.1 2.2 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain polyprenyl_synt PF00348.17 AIM20568.1 - 1.1e-56 191.8 0.3 1.4e-56 191.4 0.3 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase DUF2880 PF11082.8 AIM20568.1 - 0.089 13.1 0.1 0.42 11.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2880) Exonuc_VII_S PF02609.16 AIM20569.1 - 2.2e-17 62.8 0.8 2.6e-17 62.6 0.8 1.1 1 0 0 1 1 1 1 Exonuclease VII small subunit Ntox17 PF15524.6 AIM20569.1 - 0.2 12.0 0.0 0.21 11.9 0.0 1.2 1 0 0 1 1 1 0 Novel toxin 17 ThiI PF02568.14 AIM20570.1 - 6.5e-79 264.1 0.0 1.1e-78 263.4 0.0 1.4 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) THUMP PF02926.17 AIM20570.1 - 3e-23 82.5 0.3 3e-23 82.5 0.3 2.0 2 0 0 2 2 2 1 THUMP domain QueC PF06508.13 AIM20570.1 - 0.00027 20.5 0.0 0.27 10.7 0.0 2.9 2 1 0 2 2 2 2 Queuosine biosynthesis protein QueC Diphthami_syn_2 PF01902.17 AIM20570.1 - 0.0009 18.8 0.0 0.0089 15.5 0.0 2.4 2 0 0 2 2 2 1 Diphthamide synthase Rhodanese PF00581.20 AIM20570.1 - 0.0068 16.9 0.3 0.14 12.6 0.1 2.8 2 1 0 2 2 2 1 Rhodanese-like domain tRNA_Me_trans PF03054.16 AIM20570.1 - 0.024 13.4 0.2 0.097 11.4 0.0 2.1 2 0 0 2 2 2 0 tRNA methyl transferase NAD_synthase PF02540.17 AIM20570.1 - 0.085 12.0 0.2 0.97 8.5 0.0 2.1 2 0 0 2 2 2 0 NAD synthase DJ-1_PfpI PF01965.24 AIM20571.1 - 5.5e-43 146.6 0.0 6.9e-43 146.3 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family ApbA_C PF08546.11 AIM20572.1 - 2.5e-34 118.2 0.1 3.8e-34 117.6 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 AIM20572.1 - 3.2e-25 88.5 0.0 5.6e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 AIM20572.1 - 0.11 13.1 0.0 0.47 11.1 0.0 2.1 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF520 PF04461.13 AIM20573.1 - 1.3e-66 223.6 2.2 1.5e-66 223.5 2.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF520) Microtub_bd PF16796.5 AIM20573.1 - 0.029 14.3 0.2 0.062 13.2 0.1 1.5 1 1 1 2 2 2 0 Microtubule binding Kinesin PF00225.23 AIM20573.1 - 0.035 13.0 0.2 0.039 12.9 0.2 1.3 1 1 0 1 1 1 0 Kinesin motor domain EXOSC1 PF10447.9 AIM20573.1 - 0.062 13.9 0.7 0.11 13.2 0.6 1.4 1 1 0 1 1 1 0 Exosome component EXOSC1/CSL4 MFS_1 PF07690.16 AIM20574.1 - 1.8e-45 155.4 61.7 4.5e-43 147.5 45.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AIM20574.1 - 2.9e-09 36.3 37.9 1.2e-07 31.0 15.6 2.6 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 AIM20574.1 - 0.00026 19.7 22.9 0.00026 19.7 22.9 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 AIM20574.1 - 0.00043 19.3 30.4 0.03 13.2 20.2 2.9 1 1 1 2 2 2 2 MFS_1 like family PUCC PF03209.15 AIM20574.1 - 0.3 10.0 36.1 1 8.3 3.3 2.9 1 1 1 2 2 2 0 PUCC protein LacY_symp PF01306.19 AIM20574.1 - 1.4 7.6 27.9 0.013 14.3 7.7 2.3 1 1 0 2 2 2 0 LacY proton/sugar symporter UbiA PF01040.18 AIM20575.1 - 1.4e-60 204.8 22.9 1.7e-60 204.5 22.9 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Deltameth_res PF16020.5 AIM20575.1 - 0.84 9.6 0.1 0.84 9.6 0.1 2.8 4 0 0 4 4 4 0 Deltamethrin resistance ETRAMP PF09716.10 AIM20575.1 - 3.4 7.8 8.6 0.68 10.0 0.1 3.0 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) COX14 PF14880.6 AIM20575.1 - 7 6.6 0.0 7 6.6 0.0 4.5 5 0 0 5 5 5 0 Cytochrome oxidase c assembly COX4_pro PF03626.14 AIM20576.1 - 2.5e-18 66.3 14.1 3.1e-18 65.9 14.1 1.1 1 0 0 1 1 1 1 Prokaryotic Cytochrome C oxidase subunit IV SID-1_RNA_chan PF13965.6 AIM20576.1 - 0.026 13.0 4.4 0.029 12.8 4.4 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Polysacc_synt_C PF14667.6 AIM20576.1 - 0.081 13.0 14.1 0.11 12.5 14.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain DUF3040 PF11239.8 AIM20576.1 - 0.091 13.0 5.9 0.098 12.9 2.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) ECF_trnsprt PF12822.7 AIM20576.1 - 0.1 12.7 12.7 0.13 12.3 12.7 1.1 1 0 0 1 1 1 0 ECF transporter, substrate-specific component SLT_beta PF02258.16 AIM20576.1 - 0.12 12.4 0.1 0.27 11.3 0.1 1.6 1 0 0 1 1 1 0 Shiga-like toxin beta subunit DUF1218 PF06749.12 AIM20576.1 - 0.16 12.5 9.7 2.3 8.8 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1218) ESSS PF10183.9 AIM20576.1 - 0.23 11.7 0.8 0.36 11.0 0.2 1.7 1 1 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) MARVEL PF01284.23 AIM20576.1 - 0.24 11.4 10.1 0.3 11.1 10.1 1.1 1 0 0 1 1 1 0 Membrane-associating domain DUF1772 PF08592.11 AIM20576.1 - 0.25 11.7 7.5 0.79 10.0 7.4 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) DUF2407_C PF13373.6 AIM20576.1 - 0.43 10.8 1.8 0.41 10.8 0.2 1.7 2 0 0 2 2 2 0 DUF2407 C-terminal domain DUF5518 PF17647.1 AIM20576.1 - 5.1 7.3 16.8 0.85 9.8 6.0 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5518) Ac76 PF05814.11 AIM20576.1 - 9 6.4 11.2 0.31 11.1 3.8 1.9 1 1 1 2 2 2 0 Orf76 (Ac76) COX3 PF00510.18 AIM20577.1 - 2.8e-16 60.2 18.9 3.6e-16 59.8 18.9 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit III COX1 PF00115.20 AIM20578.1 - 7.3e-136 453.4 71.7 7.3e-136 453.4 71.7 2.4 3 0 0 3 3 3 1 Cytochrome C and Quinol oxidase polypeptide I Sigma_reg_N PF13800.6 AIM20578.1 - 0.52 10.6 6.3 0.2 11.9 0.7 3.2 1 1 1 2 2 2 0 Sigma factor regulator N-terminal COX_ARM PF06481.14 AIM20579.1 - 2e-20 72.4 0.2 3.7e-20 71.6 0.2 1.5 1 0 0 1 1 1 1 COX Aromatic Rich Motif COX2 PF00116.20 AIM20579.1 - 1.1e-05 25.3 0.0 4.1e-05 23.4 0.0 1.8 1 1 1 2 2 2 1 Cytochrome C oxidase subunit II, periplasmic domain HisKA_7TM PF16927.5 AIM20579.1 - 0.0033 17.5 1.6 0.0047 17.0 1.6 1.2 1 0 0 1 1 1 1 N-terminal 7TM region of histidine kinase COX2_TM PF02790.15 AIM20579.1 - 0.022 14.9 3.2 0.042 14.0 3.2 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane domain MAPEG PF01124.18 AIM20579.1 - 0.045 13.7 0.6 0.087 12.7 0.6 1.5 1 0 0 1 1 1 0 MAPEG family DUF4079 PF13301.6 AIM20579.1 - 0.079 13.1 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) SdpI PF13630.6 AIM20579.1 - 0.11 12.7 4.8 1.6 8.9 1.7 2.5 2 0 0 2 2 2 0 SdpI/YhfL protein family Lambda_Kil PF06301.11 AIM20579.1 - 0.13 11.9 0.4 0.3 10.7 0.4 1.6 1 0 0 1 1 1 0 Bacteriophage lambda Kil protein TspO_MBR PF03073.15 AIM20579.1 - 0.13 12.3 5.3 0.3 11.1 5.3 1.6 1 1 0 1 1 1 0 TspO/MBR family MFS_1 PF07690.16 AIM20580.1 - 2.9e-34 118.6 62.7 5.9e-32 111.0 39.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Acatn PF13000.7 AIM20580.1 - 3.3e-10 39.1 7.8 2.1e-08 33.1 7.8 2.3 1 1 0 1 1 1 1 Acetyl-coenzyme A transporter 1 Lipoprotein_16 PF03923.13 AIM20581.1 - 6.2e-54 181.9 2.4 7.2e-54 181.7 2.4 1.0 1 0 0 1 1 1 1 Uncharacterized lipoprotein AcylCoA_DH_N PF12418.8 AIM20581.1 - 0.013 15.5 0.1 0.024 14.7 0.1 1.4 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase N terminal DUF4952 PF16310.5 AIM20581.1 - 0.12 12.6 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 Domian of unknown function (DUF4952) LPAM_1 PF08139.12 AIM20581.1 - 1.4 9.6 5.1 2.5 8.8 5.1 1.4 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site BolA PF01722.18 AIM20582.1 - 9e-28 96.4 0.1 1.1e-27 96.2 0.1 1.1 1 0 0 1 1 1 1 BolA-like protein Trigger_N PF05697.13 AIM20583.1 - 1e-44 152.3 2.4 1e-44 152.3 2.4 2.9 3 1 1 4 4 4 1 Bacterial trigger factor protein (TF) Trigger_C PF05698.14 AIM20583.1 - 4.9e-40 137.2 7.3 4.9e-40 137.2 7.3 3.1 4 0 0 4 4 4 1 Bacterial trigger factor protein (TF) C-terminus FKBP_C PF00254.28 AIM20583.1 - 3.6e-15 56.1 0.7 1.1e-14 54.5 0.2 2.1 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF4172 PF13776.6 AIM20583.1 - 0.032 14.6 2.0 1.8 9.0 0.1 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4172) PDZ_4 PF17816.1 AIM20583.1 - 0.17 12.3 2.2 10 6.6 0.1 2.6 2 0 0 2 2 2 0 PDZ domain DUF3811 PF11656.8 AIM20583.1 - 0.19 12.2 2.3 0.29 11.5 0.1 2.4 2 0 0 2 2 2 0 YjbD family (DUF3811) Arabinose_Isome PF02610.15 AIM20583.1 - 1.4 8.1 6.6 0.55 9.4 0.9 2.5 3 0 0 3 3 3 0 L-arabinose isomerase CLP_protease PF00574.23 AIM20584.1 - 1e-90 302.5 0.0 1.2e-90 302.3 0.0 1.0 1 0 0 1 1 1 1 Clp protease AAA_2 PF07724.14 AIM20585.1 - 4.9e-48 163.5 0.0 7.9e-48 162.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) zf-C4_ClpX PF06689.13 AIM20585.1 - 4.4e-21 74.5 3.8 1.3e-20 72.9 3.8 1.9 1 0 0 1 1 1 1 ClpX C4-type zinc finger ClpB_D2-small PF10431.9 AIM20585.1 - 2.3e-17 62.8 1.8 4e-17 62.0 0.2 2.2 3 0 0 3 3 2 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 AIM20585.1 - 2.7e-15 57.0 0.0 6.7e-15 55.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 AIM20585.1 - 6.8e-07 28.9 0.1 0.00035 20.0 0.2 3.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 AIM20585.1 - 1.7e-06 28.3 0.1 1.7e-05 25.1 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 AIM20585.1 - 2.2e-06 27.7 0.0 1.7e-05 24.8 0.1 2.4 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) MCM PF00493.23 AIM20585.1 - 4.9e-06 25.8 0.0 8e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain RuvB_N PF05496.12 AIM20585.1 - 6.1e-06 26.1 0.1 1.8e-05 24.5 0.1 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 AIM20585.1 - 0.00047 20.6 0.0 0.0015 18.9 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 AIM20585.1 - 0.00075 19.1 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region Sigma54_activat PF00158.26 AIM20585.1 - 0.00084 19.1 0.2 0.18 11.5 0.0 2.6 3 0 0 3 3 2 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AIM20585.1 - 0.0021 18.2 0.0 0.0052 16.9 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_24 PF13479.6 AIM20585.1 - 0.0024 17.6 0.1 0.004 16.9 0.1 1.4 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 AIM20585.1 - 0.0036 16.4 0.0 0.0068 15.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein TIP49 PF06068.13 AIM20585.1 - 0.0043 16.3 0.0 0.014 14.6 0.0 1.6 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_14 PF13173.6 AIM20585.1 - 0.0083 16.2 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 AIM20585.1 - 0.009 15.8 0.1 0.017 14.9 0.1 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein ATPase PF06745.13 AIM20585.1 - 0.0094 15.3 0.2 1.5 8.2 0.0 2.4 2 0 0 2 2 2 1 KaiC ABC_tran PF00005.27 AIM20585.1 - 0.017 15.6 0.0 0.053 14.0 0.0 1.9 2 0 0 2 2 1 0 ABC transporter AAA_21 PF13304.6 AIM20585.1 - 0.02 14.7 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 AIM20585.1 - 0.02 14.8 0.0 0.43 10.5 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.6 AIM20585.1 - 0.026 14.7 0.0 0.062 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AIM20585.1 - 0.029 14.9 0.0 0.11 13.1 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_15 PF13175.6 AIM20585.1 - 0.042 13.5 0.3 0.59 9.8 0.0 2.2 2 1 1 3 3 3 0 AAA ATPase domain TsaE PF02367.17 AIM20585.1 - 0.049 13.6 0.1 0.1 12.6 0.1 1.5 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DEAD PF00270.29 AIM20585.1 - 0.099 12.4 0.9 0.4 10.4 0.9 2.4 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_29 PF13555.6 AIM20585.1 - 0.11 12.3 0.1 0.27 11.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF1296 PF06972.11 AIM20585.1 - 0.12 12.5 0.0 0.41 10.8 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) PhoH PF02562.16 AIM20585.1 - 0.12 11.8 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_8 PF12780.7 AIM20585.1 - 0.14 11.5 0.0 0.36 10.1 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region D4 ResIII PF04851.15 AIM20585.1 - 0.14 12.2 0.1 0.54 10.2 0.2 2.1 2 1 0 2 2 1 0 Type III restriction enzyme, res subunit AAA_28 PF13521.6 AIM20585.1 - 0.17 12.1 0.0 0.38 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 AIM20585.1 - 0.17 12.3 0.0 0.46 10.9 0.0 1.8 1 1 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 AIM20585.1 - 0.21 11.9 0.6 6 7.2 0.1 2.6 1 1 1 2 2 2 0 AAA domain AAA_23 PF13476.6 AIM20585.1 - 0.54 10.7 3.4 1.1 9.8 3.4 1.8 1 1 0 1 1 1 0 AAA domain Lon_C PF05362.13 AIM20586.1 - 2.1e-97 324.6 0.2 3.6e-97 323.9 0.2 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 AIM20586.1 - 1.3e-43 149.3 0.2 1.3e-43 149.3 0.2 1.8 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 AIM20586.1 - 7.4e-18 65.3 0.0 1.8e-17 64.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AIM20586.1 - 4.7e-10 39.6 0.0 2.2e-09 37.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 AIM20586.1 - 2.3e-07 30.7 0.0 5e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_PrkA PF08298.11 AIM20586.1 - 5.1e-06 25.6 0.0 9.4e-06 24.8 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain AAA_16 PF13191.6 AIM20586.1 - 5.1e-05 23.7 0.0 0.00035 21.0 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 AIM20586.1 - 0.00064 19.5 0.0 0.0016 18.2 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 AIM20586.1 - 0.0012 18.6 0.0 0.0036 17.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 AIM20586.1 - 0.0052 16.5 0.0 0.03 14.1 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 AIM20586.1 - 0.0082 16.4 0.2 0.11 12.8 0.2 2.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 AIM20586.1 - 0.0089 16.1 0.0 0.035 14.1 0.0 2.1 2 0 0 2 2 1 1 AAA domain NACHT PF05729.12 AIM20586.1 - 0.014 15.3 0.0 0.35 10.8 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.6 AIM20586.1 - 0.017 15.6 0.0 0.017 15.6 0.0 2.8 3 1 0 3 3 1 0 AAA domain AAA_33 PF13671.6 AIM20586.1 - 0.025 14.7 0.3 0.12 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 AIM20586.1 - 0.051 13.5 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase T3SSipB PF16535.5 AIM20586.1 - 0.088 13.3 3.1 0.17 12.3 3.1 1.5 1 0 0 1 1 1 0 Type III cell invasion protein SipB TsaE PF02367.17 AIM20586.1 - 0.13 12.3 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 AIM20586.1 - 0.15 12.5 0.0 0.61 10.5 0.0 2.1 2 0 0 2 2 2 0 RNA helicase ECH_2 PF16113.5 AIM20586.1 - 0.21 11.1 3.0 0.59 9.6 1.7 2.2 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase DUF3896 PF13035.6 AIM20586.1 - 0.44 10.7 5.0 4.1 7.6 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) ABC_tran PF00005.27 AIM20586.1 - 0.72 10.4 2.4 1.6 9.2 0.0 2.5 2 1 0 2 2 2 0 ABC transporter AAA_23 PF13476.6 AIM20586.1 - 0.81 10.2 8.2 26 5.2 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.6 AIM20586.1 - 9.1 6.7 7.9 2.1 8.8 0.1 3.3 3 0 0 3 3 3 0 AAA domain Bac_DNA_binding PF00216.21 AIM20587.1 - 3.6e-33 113.6 0.1 4e-33 113.5 0.1 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 AIM20587.1 - 4.3e-07 30.1 0.0 4.7e-07 30.0 0.0 1.0 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_euk_2 PF18289.1 AIM20587.1 - 0.0086 16.2 0.0 0.012 15.7 0.0 1.2 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 HU-CCDC81_bac_2 PF18175.1 AIM20587.1 - 0.018 14.9 0.0 0.025 14.4 0.0 1.2 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 SurA_N_3 PF13624.6 AIM20588.1 - 1.1e-51 174.8 8.2 1.1e-51 174.8 8.2 2.4 2 0 0 2 2 2 1 SurA N-terminal domain SurA_N_2 PF13623.6 AIM20588.1 - 3.4e-37 127.5 2.8 3.4e-37 127.5 2.8 2.7 2 0 0 2 2 2 1 SurA N-terminal domain Rotamase_2 PF13145.6 AIM20588.1 - 2.1e-33 115.7 24.3 1.9e-23 83.6 0.4 5.1 5 0 0 5 5 5 3 PPIC-type PPIASE domain Rotamase_3 PF13616.6 AIM20588.1 - 1.8e-14 54.3 0.2 1.8e-14 54.3 0.2 3.2 3 1 0 3 3 3 1 PPIC-type PPIASE domain Rotamase PF00639.21 AIM20588.1 - 1.4e-13 51.6 0.1 1.4e-13 51.6 0.1 3.6 4 0 0 4 4 4 1 PPIC-type PPIASE domain SurA_N PF09312.11 AIM20588.1 - 3.5e-06 27.1 2.8 2.1e-05 24.6 1.9 2.7 2 0 0 2 2 2 1 SurA N-terminal domain SLIDE PF09111.10 AIM20588.1 - 0.12 12.4 1.0 0.24 11.5 0.1 2.1 2 0 0 2 2 2 0 SLIDE HHH_3 PF12836.7 AIM20589.1 - 1.2e-21 76.7 0.1 1.6e-21 76.3 0.1 1.2 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.23 AIM20589.1 - 3e-09 36.3 0.2 0.0017 18.2 0.1 2.3 2 0 0 2 2 2 2 Helix-hairpin-helix motif T2SSK PF03934.13 AIM20589.1 - 0.00018 21.0 0.1 0.00061 19.3 0.1 1.8 1 1 0 1 1 1 1 Type II secretion system (T2SS), protein K HHH_5 PF14520.6 AIM20589.1 - 0.002 18.7 0.2 2.3 8.9 0.0 2.3 2 0 0 2 2 2 2 Helix-hairpin-helix domain HHH_6 PF14579.6 AIM20589.1 - 0.0032 17.7 0.0 0.011 15.9 0.0 1.8 1 1 1 2 2 2 1 Helix-hairpin-helix motif HHH_2 PF12826.7 AIM20589.1 - 0.05 13.7 0.1 13 5.9 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif HHH_8 PF14716.6 AIM20589.1 - 0.066 13.6 0.1 0.81 10.1 0.0 2.2 1 1 1 2 2 2 0 Helix-hairpin-helix domain PG_binding_2 PF08823.11 AIM20589.1 - 0.13 12.6 0.1 0.27 11.6 0.0 1.6 2 0 0 2 2 2 0 Putative peptidoglycan binding domain ACC_epsilon PF13822.6 AIM20589.1 - 8.6 7.1 10.4 11 6.7 5.2 2.4 2 1 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit QueC PF06508.13 AIM20590.1 - 2.4e-82 275.5 0.1 2.7e-82 275.3 0.1 1.0 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Arginosuc_synth PF00764.19 AIM20590.1 - 0.00067 19.1 0.1 0.0011 18.4 0.1 1.3 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.21 AIM20590.1 - 0.00095 18.9 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase PAPS_reduct PF01507.19 AIM20590.1 - 0.0013 18.8 0.0 0.0054 16.8 0.0 1.8 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.20 AIM20590.1 - 0.0057 16.4 0.1 0.011 15.4 0.1 1.5 2 0 0 2 2 2 1 PP-loop family Diphthami_syn_2 PF01902.17 AIM20590.1 - 0.012 15.2 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Diphthamide synthase NAD_synthase PF02540.17 AIM20590.1 - 0.019 14.1 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 NAD synthase ThiI PF02568.14 AIM20590.1 - 0.053 13.1 0.1 0.19 11.3 0.1 1.8 1 1 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) SgrR_N PF12793.7 AIM20591.1 - 1.4e-37 128.4 2.7 3.2e-37 127.3 2.7 1.6 1 0 0 1 1 1 1 Sugar transport-related sRNA regulator N-term SBP_bac_5 PF00496.22 AIM20591.1 - 6.1e-20 71.5 0.0 1.3e-19 70.5 0.0 1.5 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 5 Middle Rrf2 PF02082.20 AIM20591.1 - 0.1 13.0 0.0 0.23 11.8 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator SOAR PF16533.5 AIM20591.1 - 0.1 12.6 0.1 0.34 10.9 0.1 1.9 1 0 0 1 1 1 0 STIM1 Orai1-activating region HTH_11 PF08279.12 AIM20591.1 - 0.11 12.5 0.1 0.87 9.6 0.0 2.5 3 0 0 3 3 3 0 HTH domain CtsR_C PF17727.1 AIM20591.1 - 0.13 12.4 0.0 12 6.1 0.1 2.7 2 0 0 2 2 2 0 CtsR C-terminal dimerization domain Clathrin_H_link PF13838.6 AIM20591.1 - 1 9.3 4.2 1.2 9.1 0.1 2.5 2 0 0 2 2 2 0 Clathrin-H-link TPR_14 PF13428.6 AIM20591.1 - 1.2 10.1 4.6 4 8.5 0.8 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Hydrolase_3 PF08282.12 AIM20592.1 - 1.2e-52 179.3 0.0 1.3e-52 179.1 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 AIM20592.1 - 5.3e-20 72.0 0.0 1.2e-17 64.3 0.0 2.1 1 1 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 AIM20592.1 - 8.3e-07 29.5 0.2 0.0072 16.6 0.0 2.5 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 AIM20592.1 - 0.01 16.3 1.7 1 9.7 0.0 2.9 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AIM20592.1 - 0.01 15.9 0.0 0.029 14.5 0.0 1.7 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.16 AIM20592.1 - 0.037 13.1 0.0 0.92 8.6 0.0 2.1 2 0 0 2 2 2 0 Trehalose-phosphatase PALP PF00291.25 AIM20593.1 - 1.1e-44 153.0 0.0 1.3e-44 152.7 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme AsnC_trans_reg PF01037.21 AIM20594.1 - 1.8e-20 72.6 0.0 2.7e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 AIM20594.1 - 3.2e-17 61.8 0.0 4.6e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 AIM20594.1 - 6.1e-14 51.6 0.1 9.4e-14 51.0 0.1 1.3 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain MarR PF01047.22 AIM20594.1 - 0.0052 16.7 0.0 0.0081 16.1 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_Crp_2 PF13545.6 AIM20594.1 - 0.0092 15.9 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain LexA_DNA_bind PF01726.16 AIM20594.1 - 0.02 14.6 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 LexA DNA binding domain HTH_20 PF12840.7 AIM20594.1 - 0.041 14.0 0.0 0.066 13.3 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_27 PF13463.6 AIM20594.1 - 0.061 13.8 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_11 PF08279.12 AIM20594.1 - 0.063 13.2 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 HTH domain GYD PF08734.11 AIM20594.1 - 0.095 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 GYD domain ABC_membrane PF00664.23 AIM20595.1 - 1.3e-38 133.2 8.2 1.7e-38 132.9 8.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 AIM20595.1 - 6.2e-31 107.7 0.1 1.5e-30 106.5 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.6 AIM20595.1 - 0.00033 20.9 0.2 0.0025 18.1 0.2 2.4 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AIM20595.1 - 0.0009 19.2 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 AIM20595.1 - 0.0023 17.4 0.0 0.021 14.2 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AIM20595.1 - 0.014 15.2 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AIM20595.1 - 0.021 14.5 0.0 0.057 13.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 AIM20595.1 - 0.065 13.7 0.0 0.12 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 AIM20595.1 - 0.09 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 NTPase Rad17 PF03215.15 AIM20595.1 - 0.098 12.6 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_18 PF13238.6 AIM20595.1 - 0.11 13.0 0.0 0.48 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 AIM20595.1 - 0.12 12.1 0.1 14 5.4 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein ABC_membrane PF00664.23 AIM20596.1 - 1.3e-39 136.6 9.0 1.6e-39 136.2 9.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 AIM20596.1 - 6.3e-29 101.2 0.0 1.1e-28 100.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AIM20596.1 - 2.5e-07 30.4 1.0 0.00018 21.0 0.1 2.2 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 AIM20596.1 - 3.6e-05 23.0 0.0 6.9e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.6 AIM20596.1 - 0.00013 22.4 0.3 0.00048 20.5 0.3 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AIM20596.1 - 0.0011 19.2 1.1 0.022 15.0 1.1 2.4 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AIM20596.1 - 0.0012 18.8 0.0 0.0025 17.7 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 AIM20596.1 - 0.0031 17.2 0.6 0.018 14.8 0.1 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 AIM20596.1 - 0.0045 17.1 0.1 0.01 15.9 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_23 PF13476.6 AIM20596.1 - 0.0048 17.4 0.0 0.0096 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Dynamin_N PF00350.23 AIM20596.1 - 0.032 14.3 0.4 0.062 13.3 0.0 1.7 2 0 0 2 2 2 0 Dynamin family DEAD PF00270.29 AIM20596.1 - 0.041 13.6 0.3 0.3 10.8 0.3 2.1 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_33 PF13671.6 AIM20596.1 - 0.051 13.7 0.4 0.12 12.5 0.4 1.9 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AIM20596.1 - 0.086 12.4 2.1 0.76 9.3 2.1 2.2 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 AIM20596.1 - 0.09 12.1 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 AIM20596.1 - 0.18 11.0 0.0 0.34 10.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF87 PF01935.17 AIM20596.1 - 0.19 11.8 1.0 0.45 10.6 1.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain P-II PF00543.22 AIM20597.1 - 1.3e-41 141.3 1.3 1.5e-41 141.1 1.3 1.0 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II DUF3240 PF11582.8 AIM20597.1 - 0.03 14.4 0.0 0.053 13.7 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3240) DUF2344 PF10105.9 AIM20597.1 - 0.086 12.7 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) Ammonium_transp PF00909.21 AIM20598.1 - 3.3e-123 411.3 44.3 3.8e-123 411.1 44.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Acyl_CoA_thio PF02551.15 AIM20599.1 - 2.3e-63 211.9 0.0 4.5e-47 159.2 0.0 3.0 2 1 0 2 2 2 2 Acyl-CoA thioesterase 4HBT_3 PF13622.6 AIM20599.1 - 1.7e-61 208.7 0.0 2e-61 208.4 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 AIM20599.1 - 0.00013 22.2 0.0 0.00066 20.0 0.0 2.0 2 0 0 2 2 2 1 Thioesterase superfamily YscW PF09619.10 AIM20600.1 - 1.2e-39 134.9 0.2 1.8e-39 134.4 0.2 1.2 1 0 0 1 1 1 1 Type III secretion system lipoprotein chaperone (YscW) DNA_binding_1 PF01035.20 AIM20601.1 - 1.8e-27 95.2 0.1 2.1e-27 95.1 0.1 1.0 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Trans_reg_C PF00486.28 AIM20602.1 - 8.8e-15 54.6 0.1 1.5e-14 53.8 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal FidL_like PF15941.5 AIM20603.1 - 9.6e-12 45.2 0.1 2.1e-11 44.1 0.1 1.6 1 0 0 1 1 1 1 FidL-like putative membrane protein PIN_11 PF18479.1 AIM20603.1 - 0.015 15.4 0.3 0.22 11.7 0.0 2.1 1 1 1 2 2 2 0 PIN like domain Trans_reg_C PF00486.28 AIM20604.1 - 0.12 12.5 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal DUF3421 PF11901.8 AIM20604.1 - 0.13 12.2 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3421) T2SSC PF11356.8 AIM20605.1 - 5.8e-14 52.2 0.0 6.9e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Type II secretion system protein C Secretin PF00263.21 AIM20606.1 - 3.2e-48 163.6 6.5 7.4e-48 162.4 6.5 1.7 1 0 0 1 1 1 1 Bacterial type II and III secretion system protein Secretin_N PF03958.17 AIM20606.1 - 2.7e-43 146.3 14.1 8.4e-18 64.6 2.8 4.1 4 0 0 4 4 4 3 Bacterial type II/III secretion system short domain Peptidase_M55 PF04951.13 AIM20606.1 - 0.039 13.4 1.4 0.07 12.5 1.4 1.3 1 0 0 1 1 1 0 D-aminopeptidase Pro_Al_protease PF02983.14 AIM20606.1 - 0.048 13.7 2.3 15 5.7 0.0 3.3 2 1 0 2 2 2 0 Alpha-lytic protease prodomain T2SSE PF00437.20 AIM20607.1 - 2.1e-90 302.5 4.6 2.7e-90 302.1 4.6 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.6 AIM20607.1 - 2e-05 25.1 1.5 6.6e-05 23.4 0.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 AIM20607.1 - 2.1e-05 24.8 0.0 7.1e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AIM20607.1 - 0.00024 20.9 0.0 0.00055 19.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 AIM20607.1 - 0.00042 20.8 0.1 0.0017 18.9 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 AIM20607.1 - 0.00047 19.8 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_7 PF12775.7 AIM20607.1 - 0.00057 19.4 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_11 PF13086.6 AIM20607.1 - 0.0012 18.7 0.0 0.002 18.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 AIM20607.1 - 0.0013 18.7 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_14 PF13173.6 AIM20607.1 - 0.0015 18.6 0.0 0.0028 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 AIM20607.1 - 0.0019 18.7 1.3 0.0021 18.6 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.6 AIM20607.1 - 0.0052 17.3 0.2 0.081 13.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.9 AIM20607.1 - 0.0057 15.6 0.0 0.0092 14.9 0.0 1.2 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_5 PF07728.14 AIM20607.1 - 0.0066 16.5 0.1 0.014 15.4 0.1 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.18 AIM20607.1 - 0.012 15.0 0.1 0.032 13.6 0.1 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF87 PF01935.17 AIM20607.1 - 0.014 15.5 0.1 0.034 14.3 0.0 1.6 2 0 0 2 2 1 0 Helicase HerA, central domain NTPase_1 PF03266.15 AIM20607.1 - 0.017 15.1 0.2 0.15 12.0 0.1 2.2 1 1 0 2 2 2 0 NTPase ATPase_2 PF01637.18 AIM20607.1 - 0.021 14.8 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea cobW PF02492.19 AIM20607.1 - 0.027 14.1 0.0 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 AIM20607.1 - 0.04 14.3 0.0 0.096 13.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.9 AIM20607.1 - 0.048 12.9 0.0 0.075 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_21 PF13304.6 AIM20607.1 - 0.068 13.0 0.0 0.18 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_19 PF13245.6 AIM20607.1 - 0.075 13.4 0.1 0.23 11.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 AIM20607.1 - 0.088 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA PF00004.29 AIM20607.1 - 0.095 13.1 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 AIM20607.1 - 0.096 12.0 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ResIII PF04851.15 AIM20607.1 - 0.17 11.9 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_8 PF12780.7 AIM20607.1 - 0.18 11.1 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 zinc_ribbon_4 PF13717.6 AIM20607.1 - 1.3 9.0 3.5 1.3 9.0 0.1 2.6 3 0 0 3 3 3 0 zinc-ribbon domain T2SSF PF00482.23 AIM20608.1 - 3e-51 172.6 19.9 3.7e-30 104.4 3.3 2.4 2 0 0 2 2 2 2 Type II secretion system (T2SS), protein F T2SSG PF08334.11 AIM20609.1 - 3.1e-36 123.7 0.1 3.7e-36 123.5 0.1 1.0 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein G N_methyl PF07963.12 AIM20609.1 - 1e-09 37.5 2.2 1.7e-09 36.8 2.2 1.4 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif ComP_DUS PF16732.5 AIM20609.1 - 0.12 13.3 0.0 0.18 12.7 0.0 1.2 1 0 0 1 1 1 0 Type IV minor pilin ComP, DNA uptake sequence receptor FUSC PF04632.12 AIM20609.1 - 0.22 10.0 0.0 0.28 9.7 0.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family N_methyl PF07963.12 AIM20610.1 - 4.9e-05 22.7 4.0 7.4e-05 22.1 4.0 1.3 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif TUDOR_5 PF18359.1 AIM20610.1 - 0.17 11.6 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain 1 T2SSI PF02501.17 AIM20611.1 - 3.4e-23 81.6 1.6 3.9e-23 81.4 1.6 1.1 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein I T2SSJ PF11612.8 AIM20612.1 - 5.9e-29 101.1 1.3 7.6e-29 100.7 1.3 1.1 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein J N_methyl PF07963.12 AIM20612.1 - 8.8e-08 31.4 2.9 1.5e-07 30.7 2.9 1.4 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif T2SSK PF03934.13 AIM20613.1 - 3.5e-06 26.6 3.8 4e-06 26.4 3.8 1.1 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein K DUF4988 PF16378.5 AIM20613.1 - 0.085 12.5 0.1 0.12 12.1 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function T2SSK PF03934.13 AIM20614.1 - 1.2e-23 83.9 0.4 3.3e-22 79.2 0.0 2.0 1 1 1 2 2 2 2 Type II secretion system (T2SS), protein K T2SSL PF05134.13 AIM20615.1 - 3.6e-35 121.4 0.1 7.3e-35 120.4 0.1 1.5 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein L GspL_C PF12693.7 AIM20615.1 - 7.4e-06 25.9 1.0 1.4e-05 25.0 1.0 1.4 1 0 0 1 1 1 1 GspL periplasmic domain Glyco_hydro_30C PF17189.4 AIM20615.1 - 0.17 12.1 0.3 0.36 11.1 0.0 1.6 2 0 0 2 2 2 0 Glycosyl hydrolase family 30 beta sandwich domain C5-epim_C PF06662.13 AIM20615.1 - 0.23 10.9 0.0 0.9 9.0 0.0 1.9 2 0 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus CLN5 PF15014.6 AIM20615.1 - 0.27 10.9 0.0 0.38 10.4 0.0 1.1 1 0 0 1 1 1 0 Ceroid-lipofuscinosis neuronal protein 5 T2SSM PF04612.12 AIM20616.1 - 8.1e-18 65.0 8.2 1.2e-17 64.5 8.2 1.4 1 1 0 1 1 1 1 Type II secretion system (T2SS), protein M HemX PF04375.14 AIM20616.1 - 0.0031 16.8 2.6 0.0041 16.5 2.6 1.1 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase Spore_III_AB PF09548.10 AIM20616.1 - 0.0097 16.0 1.1 0.014 15.5 1.1 1.2 1 0 0 1 1 1 1 Stage III sporulation protein AB (spore_III_AB) FAM117 PF15388.6 AIM20616.1 - 0.022 14.2 0.4 0.029 13.8 0.4 1.1 1 0 0 1 1 1 0 Protein Family FAM117 DUF4131 PF13567.6 AIM20616.1 - 0.024 14.3 0.2 0.038 13.6 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF3734 PF12536.8 AIM20616.1 - 0.063 13.6 1.5 0.11 12.8 1.5 1.3 1 0 0 1 1 1 0 Patatin phospholipase DUF4748 PF15932.5 AIM20616.1 - 0.084 12.6 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) ERG4_ERG24 PF01222.17 AIM20616.1 - 0.12 11.1 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family DiS_P_DiS PF06750.13 AIM20617.1 - 1.9e-31 108.0 3.4 3e-31 107.4 3.4 1.3 1 0 0 1 1 1 1 Bacterial Peptidase A24 N-terminal domain Peptidase_A24 PF01478.18 AIM20617.1 - 4.5e-18 65.6 12.7 4.5e-18 65.6 12.7 2.0 3 0 0 3 3 3 1 Type IV leader peptidase family T2SS_PulS_OutS PF09691.10 AIM20618.1 - 2e-16 60.1 0.0 2.5e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 Type II secretion system pilotin lipoprotein (PulS_OutS) LPMO_10 PF03067.15 AIM20619.1 - 8.1e-33 114.7 3.4 8.3e-33 114.7 1.9 1.8 2 0 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading GbpA_2 PF18416.1 AIM20619.1 - 3.3e-24 85.1 2.0 4.4e-24 84.7 0.6 2.0 2 0 0 2 2 2 1 N-acetylglucosamine binding protein domain 2 FlaE PF07559.14 AIM20619.1 - 0.015 15.8 3.6 3 8.5 3.6 2.5 1 1 0 1 1 1 0 Flagellar basal body protein FlaE Invasin_D3 PF09134.10 AIM20619.1 - 0.68 10.3 3.9 1.4 9.3 1.6 2.6 2 1 0 2 2 2 0 Invasin, domain 3 Ni_hydr_CYTB PF01292.20 AIM20620.1 - 5.9e-11 42.3 9.4 6.3e-11 42.2 9.4 1.0 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 DUF4405 PF14358.6 AIM20620.1 - 0.0017 18.9 6.1 0.0026 18.3 6.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4405) HHA PF05321.11 AIM20621.1 - 3.2e-33 113.8 0.5 3.6e-33 113.6 0.5 1.0 1 0 0 1 1 1 1 Haemolysin expression modulating protein YbaJ PF10757.9 AIM20622.1 - 6.5e-64 213.7 0.6 7.4e-64 213.6 0.6 1.0 1 0 0 1 1 1 1 Biofilm formation regulator YbaJ DUF2854 PF11016.8 AIM20622.1 - 0.0052 16.7 0.0 0.0066 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2854) DUF2672 PF10878.8 AIM20622.1 - 0.13 12.2 0.7 0.23 11.5 0.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2672) PKD_2 PF16407.5 AIM20623.1 - 0.045 13.9 0.0 0.045 13.9 0.0 1.1 1 0 0 1 1 1 0 PKD-like family ABC_tran PF00005.27 AIM20624.1 - 1.7e-23 83.7 0.0 3.1e-23 82.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIM20624.1 - 3.9e-10 40.0 0.2 0.00026 20.9 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIM20624.1 - 2.4e-07 30.4 0.6 0.0025 17.3 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AIM20624.1 - 5.6e-05 23.6 0.4 0.00012 22.5 0.4 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AIM20624.1 - 0.0018 18.0 0.3 0.0038 16.9 0.3 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 AIM20624.1 - 0.0093 16.2 0.1 0.15 12.3 0.1 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 AIM20624.1 - 0.015 15.5 0.1 0.038 14.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AIM20624.1 - 0.018 15.2 0.0 0.27 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 AIM20624.1 - 0.019 15.5 0.1 0.029 14.9 0.1 1.2 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 AIM20624.1 - 0.053 13.4 0.2 0.3 11.0 0.1 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA_27 PF13514.6 AIM20624.1 - 0.071 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain MukB PF04310.12 AIM20624.1 - 0.081 12.7 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 MukB N-terminal NACHT PF05729.12 AIM20624.1 - 0.11 12.4 1.5 0.35 10.8 0.1 2.2 2 1 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 AIM20624.1 - 0.15 11.8 1.0 0.48 10.1 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 AIM20624.1 - 0.18 11.5 0.1 0.25 11.0 0.1 1.1 1 0 0 1 1 1 0 AAA ATPase domain ATP_bind_1 PF03029.17 AIM20624.1 - 0.26 11.0 0.3 6.7 6.4 0.1 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ABC-3 PF00950.17 AIM20625.1 - 1.9e-50 171.8 32.4 2.1e-50 171.6 32.4 1.0 1 0 0 1 1 1 1 ABC 3 transport family FeoB_C PF07664.12 AIM20625.1 - 0.38 10.5 0.1 0.38 10.5 0.1 3.4 4 0 0 4 4 4 0 Ferrous iron transport protein B C terminus ZnuA PF01297.17 AIM20626.1 - 5.8e-78 261.8 0.0 6.5e-78 261.7 0.0 1.0 1 0 0 1 1 1 1 Zinc-uptake complex component A periplasmic Ribosomal_L36 PF00444.18 AIM20627.1 - 3.1e-17 62.5 2.6 4.1e-17 62.1 2.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L36 Ribosomal_L31 PF01197.18 AIM20628.1 - 1.9e-22 79.2 0.1 2.8e-22 78.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L31 ACR_tran PF00873.19 AIM20629.1 - 0 1425.3 13.8 0 1425.1 13.8 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AIM20629.1 - 7.7e-08 31.6 27.1 7.6e-07 28.4 11.0 2.5 2 0 0 2 2 2 2 MMPL family SecD_SecF PF02355.16 AIM20629.1 - 1.4e-07 31.1 26.8 8.5e-05 22.0 4.1 2.6 2 0 0 2 2 2 2 Protein export membrane protein HlyD_D23 PF16576.5 AIM20630.1 - 1.1e-13 50.9 1.5 1.2e-12 47.5 1.5 2.4 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD PF00529.20 AIM20630.1 - 7.6e-13 48.2 0.1 1.6e-12 47.1 0.0 1.7 2 1 0 2 2 2 1 HlyD membrane-fusion protein of T1SS HlyD_3 PF13437.6 AIM20630.1 - 4.6e-11 43.4 1.4 1.8e-07 31.8 0.1 3.3 3 1 0 3 3 3 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AIM20630.1 - 1.5e-10 40.7 1.9 7.3e-06 25.7 0.0 3.9 3 1 0 3 3 3 2 Biotin-lipoyl like TPR_8 PF13181.6 AIM20630.1 - 0.09 13.0 0.6 0.27 11.5 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat OEP PF02321.18 AIM20630.1 - 0.18 11.6 6.5 0.81 9.5 6.4 2.1 1 1 0 1 1 1 0 Outer membrane efflux protein TetR_C_2 PF08361.11 AIM20631.1 - 6.1e-42 142.5 0.2 6.9e-42 142.4 0.2 1.0 1 0 0 1 1 1 1 MAATS-type transcriptional repressor, C-terminal region TetR_C_6 PF13977.6 AIM20631.1 - 0.0003 21.0 0.2 0.00038 20.7 0.2 1.1 1 0 0 1 1 1 1 BetI-type transcriptional repressor, C-terminal DUF4260 PF14079.6 AIM20631.1 - 0.039 13.9 0.0 0.053 13.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4260) DrsE PF02635.15 AIM20632.1 - 4.6e-21 75.4 0.1 5.1e-21 75.2 0.1 1.0 1 0 0 1 1 1 1 DsrE/DsrF-like family DsrH PF04077.12 AIM20632.1 - 0.016 15.4 0.2 0.085 13.0 0.1 2.2 1 1 1 2 2 2 0 DsrH like protein MscS_TM PF12794.7 AIM20633.1 - 2.5e-94 315.9 21.1 2.5e-94 315.9 21.1 1.9 2 0 0 2 2 2 1 Mechanosensitive ion channel inner membrane domain 1 MS_channel PF00924.18 AIM20633.1 - 6.1e-59 199.0 0.4 2e-58 197.4 0.4 2.0 1 0 0 1 1 1 1 Mechanosensitive ion channel MscS_porin PF12795.7 AIM20633.1 - 6.9e-57 192.7 59.1 6.9e-57 192.7 59.1 2.7 1 1 1 2 2 2 1 Mechanosensitive ion channel porin domain PNTB PF02233.16 AIM20633.1 - 0.13 11.2 4.5 0.21 10.5 4.5 1.3 1 0 0 1 1 1 0 NAD(P) transhydrogenase beta subunit Bac_export_2 PF01312.19 AIM20633.1 - 9.2 5.4 8.3 21 4.2 7.5 2.1 1 1 0 1 1 1 0 FlhB HrpN YscU SpaS Family DUF2496 PF10689.9 AIM20634.1 - 3.5e-24 84.3 1.1 4e-24 84.1 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2496) PriC PF07445.12 AIM20635.1 - 2.3e-53 180.7 13.7 2.6e-53 180.5 13.7 1.0 1 0 0 1 1 1 1 Primosomal replication protein priC Helo_like_N PF17111.5 AIM20635.1 - 0.031 13.6 2.3 0.069 12.5 0.5 2.0 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins DUF1877 PF08974.10 AIM20635.1 - 0.033 14.3 0.3 0.047 13.8 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1877) CCDC-167 PF15188.6 AIM20635.1 - 0.034 14.5 3.3 0.62 10.4 0.2 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 SpecificRecomb PF10136.9 AIM20635.1 - 0.62 8.3 7.1 0.5 8.6 1.0 1.9 1 1 0 2 2 2 0 Site-specific recombinase Syntaxin_2 PF14523.6 AIM20635.1 - 0.69 10.3 5.0 4.2 7.8 0.7 2.4 1 1 1 2 2 2 0 Syntaxin-like protein ABC_tran_CTD PF16326.5 AIM20635.1 - 0.86 9.9 13.4 3 8.2 0.7 3.9 2 1 2 4 4 4 0 ABC transporter C-terminal domain TBCC_N PF16752.5 AIM20635.1 - 0.89 10.0 8.4 0.2 12.1 0.6 2.8 3 0 0 3 3 3 0 Tubulin-specific chaperone C N-terminal domain Prefoldin PF02996.17 AIM20635.1 - 5.5 6.9 7.9 2.5 8.0 0.3 3.0 3 1 0 4 4 4 0 Prefoldin subunit Casc1_N PF15927.5 AIM20635.1 - 6.2 6.5 11.6 0.48 10.1 4.1 2.3 1 1 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus DUF454 PF04304.13 AIM20636.1 - 4.8e-41 139.4 14.7 5.5e-41 139.2 14.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF454) Pribosyltran PF00156.27 AIM20637.1 - 5.1e-17 61.8 0.0 6.2e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 AIM20637.1 - 0.0038 16.7 0.0 0.0055 16.2 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DNA_pol3_tau_5 PF12170.8 AIM20638.1 - 1.5e-60 203.4 2.1 1.5e-60 203.4 2.1 1.9 2 0 0 2 2 2 1 DNA polymerase III tau subunit V interacting with alpha DNA_pol3_delta2 PF13177.6 AIM20638.1 - 1.2e-42 145.5 0.0 1.8e-42 144.9 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DNA_pol3_gamma3 PF12169.8 AIM20638.1 - 3.6e-33 114.5 3.1 3.6e-33 114.5 3.1 3.0 3 0 0 3 3 3 1 DNA polymerase III subunits gamma and tau domain III DNA_pol3_tau_4 PF12168.8 AIM20638.1 - 3.1e-20 72.5 9.5 3.1e-20 72.5 9.5 2.3 2 0 0 2 2 2 1 DNA polymerase III subunits tau domain IV DnaB-binding AAA PF00004.29 AIM20638.1 - 1.8e-11 44.6 0.0 7.1e-11 42.7 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 AIM20638.1 - 1.3e-06 28.3 0.0 5.8e-05 22.9 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 AIM20638.1 - 1.4e-05 25.1 0.0 3.6e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 AIM20638.1 - 1.5e-05 25.3 0.0 5.5e-05 23.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AIM20638.1 - 0.00032 21.3 0.0 0.00076 20.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 AIM20638.1 - 0.00072 19.6 0.1 0.2 11.6 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 AIM20638.1 - 0.00089 19.7 0.2 0.00089 19.7 0.2 4.3 2 2 1 3 3 2 1 AAA ATPase domain AAA_14 PF13173.6 AIM20638.1 - 0.00098 19.2 0.0 0.0026 17.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 AIM20638.1 - 0.0015 18.4 1.4 0.002 17.9 0.1 1.8 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_24 PF13479.6 AIM20638.1 - 0.0068 16.2 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 AIM20638.1 - 0.024 15.0 0.6 0.075 13.4 0.6 1.9 1 0 0 1 1 1 0 AAA C-terminal domain TIP49 PF06068.13 AIM20638.1 - 0.025 13.8 0.3 2.4 7.2 0.0 2.2 1 1 0 2 2 2 0 TIP49 P-loop domain AAA_7 PF12775.7 AIM20638.1 - 0.029 13.9 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 AIM20638.1 - 0.043 13.8 0.8 0.073 13.1 0.1 1.7 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 AIM20638.1 - 0.059 12.7 0.1 0.16 11.3 0.1 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SKI PF01202.22 AIM20638.1 - 0.097 12.8 0.2 0.36 10.9 0.1 2.0 2 0 0 2 2 1 0 Shikimate kinase AAA_33 PF13671.6 AIM20638.1 - 1.8 8.7 4.6 5 7.3 0.1 3.2 3 0 0 3 3 3 0 AAA domain YbaB_DNA_bd PF02575.16 AIM20639.1 - 6.8e-35 119.2 10.1 7.7e-35 119.0 10.1 1.0 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family IIGP PF05049.13 AIM20639.1 - 0.024 13.7 0.3 0.034 13.2 0.3 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) CARM1 PF11531.8 AIM20639.1 - 0.033 14.4 0.1 0.046 13.9 0.1 1.2 1 0 0 1 1 1 0 Coactivator-associated arginine methyltransferase 1 N terminal GIT_CC PF16559.5 AIM20639.1 - 0.047 13.5 2.6 0.094 12.6 2.6 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor AUX_IAA PF02309.16 AIM20639.1 - 0.077 12.8 0.3 0.094 12.6 0.3 1.2 1 0 0 1 1 1 0 AUX/IAA family NDUF_B5 PF09781.9 AIM20639.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit PspB PF06667.12 AIM20639.1 - 0.18 11.9 1.5 14 5.8 0.1 2.2 2 0 0 2 2 2 0 Phage shock protein B Toprim_4 PF13662.6 AIM20640.1 - 3.9e-23 81.7 0.0 6.2e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Toprim domain RecR PF02132.15 AIM20640.1 - 1.2e-15 56.8 1.2 2.5e-15 55.7 1.2 1.6 1 0 0 1 1 1 1 RecR protein Toprim PF01751.22 AIM20640.1 - 9e-11 41.9 0.0 1.7e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Toprim domain Gln-synt_N_2 PF16952.5 AIM20640.1 - 0.02 14.7 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 Glutamine synthetase N-terminal domain FYVE_2 PF02318.16 AIM20640.1 - 0.058 13.6 0.5 0.77 10.0 0.3 2.1 2 0 0 2 2 2 0 FYVE-type zinc finger HHH_5 PF14520.6 AIM20640.1 - 0.079 13.6 0.1 0.27 11.8 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix domain HHH PF00633.23 AIM20640.1 - 0.15 12.0 1.9 0.34 10.9 0.0 2.4 3 0 0 3 3 3 0 Helix-hairpin-helix motif BmKX PF09132.10 AIM20640.1 - 0.37 10.8 2.7 19 5.3 0.2 3.0 3 0 0 3 3 3 0 BmKX HSP90 PF00183.18 AIM20641.1 - 1.8e-129 433.0 0.4 5.7e-127 424.7 0.7 2.0 1 1 1 2 2 2 2 Hsp90 protein HATPase_c PF02518.26 AIM20641.1 - 2.6e-13 50.5 0.1 4.7e-13 49.6 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 AIM20641.1 - 1.1e-12 47.9 0.2 3.2e-12 46.5 0.1 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CinA_KH PF18146.1 AIM20641.1 - 0.087 13.0 0.3 13 6.0 0.1 2.9 2 0 0 2 2 2 0 Damage-inducible protein CinA KH domain ADK PF00406.22 AIM20642.1 - 4.5e-61 205.4 0.0 5.5e-61 205.1 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 AIM20642.1 - 3.3e-28 98.8 0.5 6.3e-28 97.9 0.1 1.6 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 AIM20642.1 - 2.6e-16 59.3 0.0 4.2e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid Hydin_ADK PF17213.3 AIM20642.1 - 7.2e-06 26.4 2.0 0.069 13.4 0.0 2.5 2 1 1 3 3 3 2 Hydin Adenylate kinase-like domain AAA_33 PF13671.6 AIM20642.1 - 0.0013 18.9 0.1 0.011 15.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 AIM20642.1 - 0.0047 17.5 0.0 0.0093 16.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 AIM20642.1 - 0.033 14.4 0.0 0.056 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Diacid_rec PF05651.13 AIM20643.1 - 5.7e-50 168.5 1.2 7.3e-50 168.1 0.5 1.5 2 0 0 2 2 2 1 Putative sugar diacid recognition HTH_30 PF13556.6 AIM20643.1 - 5.2e-19 67.8 1.9 5.2e-19 67.8 1.9 2.8 3 0 0 3 3 3 1 PucR C-terminal helix-turn-helix domain GGDEF_2 PF17853.1 AIM20643.1 - 2.4e-14 53.6 1.4 8.5e-14 51.8 1.4 2.0 1 0 0 1 1 1 1 GGDEF-like domain Sigma70_r4_2 PF08281.12 AIM20643.1 - 0.00048 19.7 0.6 0.38 10.4 0.0 2.9 2 0 0 2 2 2 2 Sigma-70, region 4 HTH_8 PF02954.19 AIM20643.1 - 0.002 17.9 3.0 0.0034 17.1 0.1 2.9 3 1 0 3 3 3 1 Bacterial regulatory protein, Fis family HTH_28 PF13518.6 AIM20643.1 - 0.072 13.2 1.5 0.6 10.3 0.1 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.6 AIM20643.1 - 0.094 12.5 1.4 1.8 8.4 0.1 3.5 3 0 0 3 3 3 0 Homeodomain-like domain GntP_permease PF02447.16 AIM20644.1 - 3.3e-25 88.7 44.3 1.2e-21 76.9 26.8 2.0 1 1 1 2 2 2 2 GntP family permease Na_H_antiport_2 PF13726.6 AIM20644.1 - 1.2e-15 57.4 25.3 1.2e-12 47.8 6.5 4.3 6 1 0 6 6 6 2 Na+-H+ antiporter family CitMHS PF03600.16 AIM20644.1 - 3.7e-12 46.0 42.7 7.3e-12 45.1 42.7 1.5 1 0 0 1 1 1 1 Citrate transporter Na_H_antiporter PF03553.14 AIM20644.1 - 0.0045 16.3 42.2 0.1 11.8 19.6 2.5 2 0 0 2 2 2 2 Na+/H+ antiporter family DctM PF06808.12 AIM20644.1 - 0.04 12.7 41.4 0.096 11.5 17.8 2.8 1 1 2 3 3 3 0 Tripartite ATP-independent periplasmic transporter, DctM component Lactate_perm PF02652.14 AIM20644.1 - 0.31 9.7 34.8 0.15 10.8 12.9 3.0 1 1 3 4 4 4 0 L-lactate permease Gly_kinase PF02595.15 AIM20645.1 - 1.4e-153 511.3 7.4 1.6e-153 511.1 7.4 1.0 1 0 0 1 1 1 1 Glycerate kinase family SIS_2 PF13580.6 AIM20645.1 - 0.056 13.5 0.6 2.1 8.3 0.1 2.4 2 0 0 2 2 2 0 SIS domain PS_pyruv_trans PF04230.13 AIM20645.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide pyruvyl transferase Ferrochelatase PF00762.19 AIM20646.1 - 1.5e-108 362.7 0.0 1.6e-108 362.5 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.17 AIM20646.1 - 2.8e-06 27.6 0.0 0.0065 16.8 0.0 2.5 2 0 0 2 2 2 2 CbiX PfkB PF00294.24 AIM20647.1 - 1.6e-14 53.9 0.0 1e-09 38.2 0.0 2.3 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Na_H_Exchanger PF00999.21 AIM20648.1 - 1.1e-79 268.0 48.5 1.5e-79 267.5 48.5 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TrkA_N PF02254.18 AIM20648.1 - 6.6e-23 81.2 0.1 1.1e-22 80.4 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain ApbA PF02558.16 AIM20648.1 - 7.4e-06 25.7 0.1 1.4e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DraK_HK_N PF18092.1 AIM20648.1 - 0.034 14.6 0.1 0.34 11.4 0.0 2.2 2 0 0 2 2 2 0 DraK Histidine Kinase N-terminal domain UDPG_MGDP_dh_N PF03721.14 AIM20648.1 - 0.054 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.15 AIM20648.1 - 0.054 13.7 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase FAD_binding_3 PF01494.19 AIM20648.1 - 0.063 12.5 0.4 0.1 11.8 0.4 1.2 1 0 0 1 1 1 0 FAD binding domain MFS_1 PF07690.16 AIM20649.1 - 1.5e-48 165.6 75.4 1.1e-36 126.5 40.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 AIM20649.1 - 1.1e-05 24.0 18.4 1.5e-05 23.7 18.4 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector OATP PF03137.20 AIM20649.1 - 0.00097 17.5 13.3 0.029 12.7 1.5 2.4 2 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Peptidase_M48_N PF16491.5 AIM20649.1 - 1.9 8.3 10.6 0.14 12.0 3.5 2.7 2 1 0 2 2 2 0 CAAX prenyl protease N-terminal, five membrane helices 5_nucleotid_C PF02872.18 AIM20650.1 - 1e-33 116.8 0.4 2.1e-33 115.8 0.4 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 AIM20650.1 - 1.5e-17 64.8 0.3 2.2e-17 64.2 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase HTH_18 PF12833.7 AIM20651.1 - 3.4e-18 65.7 0.2 6.2e-18 64.8 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain AraC_binding PF02311.19 AIM20651.1 - 2.4e-12 46.9 0.1 7e-12 45.4 0.0 1.7 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_2 PF07883.11 AIM20651.1 - 1.4e-05 24.7 0.0 2.2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Cupin domain HTH_AraC PF00165.23 AIM20651.1 - 0.0025 17.9 1.3 0.079 13.1 0.3 2.4 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_23 PF13384.6 AIM20651.1 - 0.046 13.5 1.2 7.2 6.5 0.4 2.7 2 1 0 2 2 2 0 Homeodomain-like domain HTH_31 PF13560.6 AIM20651.1 - 0.11 12.8 1.5 3.9 7.9 1.5 2.8 1 1 0 1 1 1 0 Helix-turn-helix domain ROS_MUCR PF05443.11 AIM20651.1 - 0.14 12.2 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 ROS/MUCR transcriptional regulator protein MFS_1 PF07690.16 AIM20652.1 - 4.4e-34 118.0 48.4 4.4e-34 118.0 48.4 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 AIM20652.1 - 0.00051 18.6 1.7 0.00095 17.7 1.7 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Thioesterase PF00975.20 AIM20653.1 - 3.3e-32 112.5 0.0 3.7e-32 112.3 0.0 1.0 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 AIM20653.1 - 8.8e-08 33.0 4.5 1.2e-07 32.5 4.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AIM20653.1 - 8.1e-06 25.7 0.0 0.00014 21.6 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AIM20653.1 - 1.8e-05 24.1 0.1 0.0012 18.2 0.1 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF1057 PF06342.12 AIM20653.1 - 0.0012 18.0 0.0 0.0018 17.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_2 PF02230.16 AIM20653.1 - 0.044 13.6 0.0 0.086 12.6 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 AIM20653.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) Esterase PF00756.20 AIM20653.1 - 0.19 11.4 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Putative esterase LIDHydrolase PF10230.9 AIM20653.1 - 0.2 11.2 0.0 0.38 10.2 0.0 1.4 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Trp_dioxygenase PF03301.13 AIM20654.1 - 3.6e-49 168.0 1.5 2.2e-30 106.2 0.2 2.0 1 1 1 2 2 2 2 Tryptophan 2,3-dioxygenase FliS PF02561.14 AIM20654.1 - 0.1 12.9 0.1 0.22 11.8 0.1 1.5 1 0 0 1 1 1 0 Flagellar protein FliS Cyclase PF04199.13 AIM20655.1 - 1.3e-10 41.6 0.0 1.8e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase DUF4625 PF15418.6 AIM20655.1 - 0.0047 17.2 0.0 0.0076 16.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4625) AMP-binding PF00501.28 AIM20656.1 - 2e-173 576.9 0.0 1.5e-90 303.9 0.0 2.4 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 AIM20656.1 - 5.7e-71 239.5 0.2 8.4e-71 239.0 0.2 1.2 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.25 AIM20656.1 - 4e-19 68.7 0.1 1.8e-08 34.6 0.1 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 AIM20656.1 - 3.2e-17 63.3 0.1 2.2e-12 47.8 0.1 2.9 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain AurF PF11583.8 AIM20657.1 - 1.4e-21 77.0 0.2 1.9e-21 76.6 0.2 1.1 1 0 0 1 1 1 1 P-aminobenzoate N-oxygenase AurF CPT_N PF16484.5 AIM20657.1 - 0.15 12.1 0.0 0.4 10.7 0.0 1.8 1 0 0 1 1 1 0 Carnitine O-palmitoyltransferase N-terminus Fer2 PF00111.27 AIM20658.1 - 1.4e-09 37.7 4.2 1.8e-09 37.4 4.2 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Peptidase_S13 PF02113.15 AIM20659.1 - 6.7e-118 394.2 1.1 7.7e-118 394.0 1.1 1.0 1 0 0 1 1 1 1 D-Ala-D-Ala carboxypeptidase 3 (S13) family Peptidase_S11 PF00768.20 AIM20659.1 - 6.8e-05 22.4 0.0 0.00012 21.6 0.0 1.3 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase tRNA_edit PF04073.15 AIM20660.1 - 2.1e-23 82.7 0.3 2.6e-23 82.4 0.3 1.1 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain DUF2330 PF10092.9 AIM20660.1 - 0.088 11.9 0.0 0.093 11.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2330) TraB PF01963.17 AIM20661.1 - 1.4e-42 146.4 0.8 1.7e-42 146.1 0.8 1.0 1 0 0 1 1 1 1 TraB family DUF2271 PF10029.9 AIM20661.1 - 0.012 15.2 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2271) E1-E2_ATPase PF00122.20 AIM20662.1 - 4e-50 169.9 2.4 1.5e-49 168.0 0.7 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 AIM20662.1 - 9e-50 169.9 4.9 9e-50 169.9 4.9 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 AIM20662.1 - 8e-37 125.5 1.1 8.3e-16 58.2 0.0 3.4 3 0 0 3 3 3 3 Heavy-metal-associated domain Hydrolase_3 PF08282.12 AIM20662.1 - 1e-09 38.6 1.5 2.6e-06 27.4 1.1 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 AIM20662.1 - 1.1e-05 25.9 0.2 0.0001 22.7 0.2 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 AIM20662.1 - 0.0091 16.1 0.1 0.042 13.9 0.1 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase T2SSF PF00482.23 AIM20662.1 - 0.018 15.0 1.6 1.6 8.7 0.2 3.3 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F SNAD4 PF18750.1 AIM20662.1 - 0.18 11.9 0.1 79 3.4 0.0 3.4 4 0 0 4 4 4 0 Secreted Novel AID/APOBEC-like Deaminase 4 DUF2207 PF09972.9 AIM20662.1 - 0.28 9.9 1.2 4.2 6.0 0.0 2.6 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) MerR_1 PF13411.6 AIM20663.1 - 5.5e-19 68.0 0.0 9.9e-19 67.2 0.0 1.4 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR-DNA-bind PF09278.11 AIM20663.1 - 2.1e-16 60.2 1.5 4.6e-16 59.1 1.4 1.6 2 0 0 2 2 2 1 MerR, DNA binding MerR PF00376.23 AIM20663.1 - 9.6e-16 57.3 0.1 2.8e-15 55.8 0.1 1.8 2 0 0 2 2 2 1 MerR family regulatory protein DUF1836 PF08876.11 AIM20663.1 - 0.0046 17.0 0.0 0.0075 16.3 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1836) HTH_Mga PF08280.11 AIM20663.1 - 0.031 14.3 0.0 0.18 11.9 0.0 2.1 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain NfeD PF01957.18 AIM20664.1 - 6e-20 71.4 0.3 6e-20 71.4 0.3 1.5 2 0 0 2 2 2 1 NfeD-like C-terminal, partner-binding Phage_holin_3_6 PF07332.11 AIM20664.1 - 0.0025 17.8 8.8 0.0036 17.3 8.8 1.4 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III DUF1970 PF09301.10 AIM20664.1 - 0.016 15.5 0.3 0.016 15.5 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1970) DUF2681 PF10883.8 AIM20664.1 - 0.4 11.1 1.4 0.52 10.8 0.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) RseC_MucC PF04246.12 AIM20664.1 - 0.64 10.0 2.9 0.47 10.4 0.9 1.9 2 1 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Band_7 PF01145.25 AIM20665.1 - 1.1e-31 110.2 0.9 1.1e-31 110.2 0.9 2.1 1 1 1 2 2 2 1 SPFH domain / Band 7 family Band_7_C PF16200.5 AIM20665.1 - 1.3e-06 28.3 0.3 2.8e-06 27.3 0.3 1.6 1 0 0 1 1 1 1 C-terminal region of band_7 Band_7_1 PF13421.6 AIM20665.1 - 0.02 14.6 0.1 0.045 13.4 0.1 1.6 2 0 0 2 2 2 0 SPFH domain-Band 7 family Flot PF15975.5 AIM20665.1 - 8.9 6.5 16.8 0.89 9.8 7.5 2.8 1 1 2 3 3 3 0 Flotillin CMAS PF02353.20 AIM20666.1 - 4.4e-101 337.8 0.2 5.5e-101 337.4 0.2 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 AIM20666.1 - 5.6e-16 59.0 0.0 1.2e-15 57.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AIM20666.1 - 3.9e-14 52.8 0.0 6e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AIM20666.1 - 4e-14 53.0 0.0 8.6e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AIM20666.1 - 7.2e-10 38.9 0.0 1.3e-09 38.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIM20666.1 - 3e-08 34.3 0.0 6.1e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AIM20666.1 - 6.2e-05 22.6 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 AIM20666.1 - 0.00015 21.9 0.0 0.00029 21.0 0.0 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.19 AIM20666.1 - 0.0014 18.4 0.0 0.0022 17.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 AIM20666.1 - 0.0046 16.9 0.0 0.0074 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 AIM20666.1 - 0.0078 15.8 0.1 0.013 15.0 0.1 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 MetW PF07021.12 AIM20666.1 - 0.014 15.0 0.1 0.022 14.3 0.1 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW ADH_zinc_N PF00107.26 AIM20666.1 - 0.038 14.0 0.0 0.068 13.2 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase TPR_20 PF14561.6 AIM20667.1 - 1e-30 105.9 5.2 1e-30 105.9 5.2 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat Thioredoxin PF00085.20 AIM20667.1 - 8.8e-20 70.6 0.0 1.9e-19 69.6 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin TPR_19 PF14559.6 AIM20667.1 - 1.3e-17 64.1 15.5 8.1e-16 58.3 3.5 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TraF PF13728.6 AIM20667.1 - 2.6e-05 24.1 1.1 3.3e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 F plasmid transfer operon protein ANAPC3 PF12895.7 AIM20667.1 - 0.00016 21.8 0.7 0.0064 16.7 0.2 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 Thioredoxin_8 PF13905.6 AIM20667.1 - 0.00025 21.3 0.2 0.017 15.5 0.0 2.9 2 1 1 3 3 3 1 Thioredoxin-like OST3_OST6 PF04756.13 AIM20667.1 - 0.00035 20.0 0.0 0.00051 19.5 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 AIM20667.1 - 0.00041 20.8 0.1 0.0017 18.8 0.0 2.0 2 1 0 2 2 2 1 Thioredoxin-like domain TPR_5 PF12688.7 AIM20667.1 - 0.03 14.6 7.8 0.077 13.2 0.9 2.4 1 1 0 2 2 2 0 Tetratrico peptide repeat HyaE PF07449.11 AIM20667.1 - 0.034 14.1 0.1 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Thioredoxin_6 PF13848.6 AIM20667.1 - 0.04 13.8 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain TPR_4 PF07721.14 AIM20667.1 - 0.53 11.1 19.4 1.9 9.4 1.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 AIM20667.1 - 2.8 9.0 19.9 2.8 9.0 1.9 5.4 1 1 5 6 6 6 0 Tetratricopeptide repeat adh_short PF00106.25 AIM20668.1 - 1.4e-43 148.7 0.0 1.6e-43 148.4 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AIM20668.1 - 3.4e-30 105.3 0.0 4.2e-30 105.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AIM20668.1 - 1.2e-11 44.9 0.0 1.9e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 AIM20668.1 - 1.4e-05 25.1 0.0 3.4e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 AIM20668.1 - 0.00016 21.3 0.1 0.0011 18.5 0.0 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 AIM20668.1 - 0.0073 15.7 0.0 0.045 13.1 0.0 1.9 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) ADH_zinc_N PF00107.26 AIM20668.1 - 0.051 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Eno-Rase_NADH_b PF12242.8 AIM20668.1 - 0.15 11.9 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DNA_pol_lambd_f PF10391.9 AIM20668.1 - 0.15 11.9 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda Lipase_GDSL_2 PF13472.6 AIM20669.1 - 1e-23 84.7 0.0 1.3e-23 84.4 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 AIM20669.1 - 4.9e-11 43.0 0.0 5.9e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase OSK PF17182.4 AIM20669.1 - 0.0062 15.8 0.0 0.011 15.0 0.0 1.3 2 0 0 2 2 2 1 OSK domain ABC_tran PF00005.27 AIM20670.1 - 5.2e-30 104.8 0.0 7e-30 104.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIM20670.1 - 1.9e-05 24.6 1.1 0.0062 16.4 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIM20670.1 - 5.7e-05 22.6 0.1 0.011 15.2 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AIM20670.1 - 0.00046 19.9 0.4 0.00086 19.0 0.4 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AIM20670.1 - 0.0018 18.2 1.9 0.0032 17.4 0.3 1.8 1 1 1 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 AIM20670.1 - 0.003 18.0 4.7 0.012 16.0 4.7 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AIM20670.1 - 0.0066 16.7 0.6 0.027 14.7 0.6 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AIM20670.1 - 0.014 15.1 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 AIM20670.1 - 0.051 13.5 0.5 0.099 12.6 0.2 1.6 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.6 AIM20670.1 - 0.14 12.7 2.0 0.88 10.1 2.0 2.1 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 AIM20670.1 - 0.2 11.7 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 AIM20670.1 - 0.26 11.5 2.1 4.5 7.4 0.1 2.4 2 1 0 2 2 2 0 AAA domain FtsX PF02687.21 AIM20671.1 - 1.2e-08 35.3 11.7 3.8e-06 27.3 0.6 5.4 5 1 0 5 5 5 2 FtsX-like permease family MacB_PCD PF12704.7 AIM20671.1 - 0.00026 21.4 0.0 0.00026 21.4 0.0 3.1 4 0 0 4 4 4 1 MacB-like periplasmic core domain SieB PF14163.6 AIM20671.1 - 1.7 8.2 3.6 4.3 6.8 0.1 2.9 3 0 0 3 3 3 0 Super-infection exclusion protein B Sugar_tr PF00083.24 AIM20672.1 - 1.9e-137 458.9 32.1 2.1e-137 458.7 32.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 AIM20672.1 - 1.2e-41 142.8 43.6 1.5e-31 109.6 17.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 AIM20672.1 - 2.1e-07 29.8 25.0 8.2e-07 27.9 8.8 3.6 3 1 1 4 4 4 2 MFS/sugar transport protein SHR3_chaperone PF08229.11 AIM20672.1 - 0.0048 15.9 3.2 0.1 11.5 0.8 2.9 2 1 1 3 3 3 2 ER membrane protein SH3 Trp_oprn_chp PF09534.10 AIM20672.1 - 1.5 8.5 11.9 2.8 7.7 2.0 3.3 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) ATP-grasp PF02222.22 AIM20673.1 - 1.7e-53 180.7 0.0 2.4e-53 180.2 0.0 1.1 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 AIM20673.1 - 1e-17 63.5 0.0 2.1e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain AIRC PF00731.20 AIM20674.1 - 4.2e-63 211.4 1.7 5e-63 211.1 1.7 1.1 1 0 0 1 1 1 1 AIR carboxylase Fe-ADH PF00465.19 AIM20674.1 - 0.0049 15.7 0.1 0.0085 14.9 0.1 1.4 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase MFMR PF07777.11 AIM20674.1 - 0.032 14.7 0.3 9.9 6.7 0.0 2.3 1 1 1 2 2 2 0 G-box binding protein MFMR PrpR_N PF06506.11 AIM20674.1 - 0.06 12.9 0.0 0.18 11.4 0.0 1.7 1 1 1 2 2 2 0 Propionate catabolism activator RraB PF06877.11 AIM20674.1 - 0.1 13.4 0.1 0.18 12.5 0.1 1.3 1 0 0 1 1 1 0 Regulator of ribonuclease activity B Metallophos_2 PF12850.7 AIM20675.1 - 2.4e-11 44.1 1.3 4.2e-10 40.1 1.3 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 AIM20675.1 - 3.1e-10 40.9 0.0 4.8e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pro_isomerase PF00160.21 AIM20676.1 - 5.8e-47 159.9 2.7 6.4e-47 159.7 2.7 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD tRNA-synt_1e PF01406.19 AIM20677.1 - 3.4e-139 463.4 0.1 4.4e-139 463.0 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DALR_2 PF09190.11 AIM20677.1 - 1.5e-25 89.4 1.1 1.5e-25 89.4 1.1 2.6 2 0 0 2 2 2 1 DALR domain tRNA-synt_1g PF09334.11 AIM20677.1 - 9.9e-13 47.6 1.4 1e-05 24.5 0.1 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 AIM20677.1 - 1.4e-05 23.6 0.1 4.3e-05 22.0 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 AIM20677.1 - 9e-05 21.5 0.0 0.017 14.0 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (K) Mut7-C PF01927.16 AIM20677.1 - 0.11 12.6 0.1 0.22 11.6 0.1 1.5 1 0 0 1 1 1 0 Mut7-C RNAse domain YdaS_antitoxin PF15943.5 AIM20677.1 - 0.23 11.3 0.5 0.68 9.8 0.1 1.9 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT S4_2 PF13275.6 AIM20678.1 - 2.6e-25 88.0 0.3 2.7e-25 87.9 0.3 1.0 1 0 0 1 1 1 1 S4 domain S4 PF01479.25 AIM20678.1 - 9.6e-05 22.0 0.1 0.00016 21.3 0.1 1.5 1 1 0 1 1 1 1 S4 domain THF_DHG_CYH_C PF02882.19 AIM20679.1 - 2.2e-69 231.9 0.1 3.2e-69 231.3 0.1 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 AIM20679.1 - 6.7e-40 136.0 0.1 1.1e-39 135.3 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain DUF2385 PF09539.10 AIM20680.1 - 0.055 14.0 0.2 0.08 13.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2385) Glyco_transf_9 PF01075.17 AIM20682.1 - 9.3e-45 152.9 0.0 1.2e-44 152.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 9 (heptosyltransferase) PS_pyruv_trans PF04230.13 AIM20682.1 - 0.0029 17.6 0.0 0.008 16.1 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide pyruvyl transferase Wzy_C PF04932.15 AIM20683.1 - 3.8e-16 59.1 1.4 3.8e-16 59.1 1.4 2.9 2 1 0 2 2 2 1 O-Antigen ligase Meckelin PF09773.9 AIM20683.1 - 0.044 11.9 2.3 0.069 11.2 2.3 1.2 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) TraQ PF09679.10 AIM20683.1 - 0.45 10.5 3.3 0.27 11.2 0.2 2.2 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) Transp_cyt_pur PF02133.15 AIM20684.1 - 2.7e-87 293.4 36.5 3.3e-87 293.1 36.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin PRD1_DD PF11087.8 AIM20684.1 - 0.021 14.5 3.0 0.38 10.5 0.5 3.2 2 0 0 2 2 2 0 PRD1 phage membrane DNA delivery GntR PF00392.21 AIM20685.1 - 6.5e-16 57.7 0.0 1.4e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family FCD PF07729.12 AIM20685.1 - 6.6e-13 49.2 1.7 6.6e-13 49.2 1.7 1.6 2 0 0 2 2 2 1 FCD domain TFIIE_alpha PF02002.17 AIM20685.1 - 0.041 13.7 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 TFIIE alpha subunit Asp_Glu_race PF01177.22 AIM20686.1 - 4.1e-12 46.4 0.9 5.4e-12 46.0 0.9 1.2 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Amdase PF17645.1 AIM20686.1 - 5.3e-06 26.2 0.6 3.1e-05 23.7 0.3 2.1 2 0 0 2 2 2 1 Arylmalonate decarboxylase Pantoate_transf PF02548.15 AIM20686.1 - 0.048 13.1 0.2 0.1 12.0 0.2 1.5 1 0 0 1 1 1 0 Ketopantoate hydroxymethyltransferase Polysacc_deac_1 PF01522.21 AIM20688.1 - 8.1e-09 35.4 0.0 1.9e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase PMT_2 PF13231.6 AIM20689.1 - 4.8e-17 62.6 21.8 4.8e-17 62.6 21.8 2.6 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF2723 PF11028.8 AIM20689.1 - 8.2e-05 22.6 11.9 8.2e-05 22.6 11.9 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2723) COX7a PF02238.15 AIM20689.1 - 1.2 9.6 5.9 0.88 10.0 1.3 3.4 2 1 0 2 2 2 0 Cytochrome c oxidase subunit VII SATase_N PF06426.14 AIM20690.1 - 5.1e-34 116.8 1.6 7.5e-34 116.3 1.6 1.2 1 0 0 1 1 1 1 Serine acetyltransferase, N-terminal Hexapep PF00132.24 AIM20690.1 - 1.8e-10 40.1 9.1 3.8e-08 32.7 4.1 2.5 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AIM20690.1 - 0.0024 17.6 9.1 0.0068 16.1 6.2 2.3 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase SieB PF14163.6 AIM20690.1 - 0.064 12.7 0.2 2 7.9 0.0 2.1 2 0 0 2 2 2 0 Super-infection exclusion protein B Aminotran_5 PF00266.19 AIM20691.1 - 9.8e-104 347.2 0.0 1.1e-103 347.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 AIM20691.1 - 1e-10 41.4 0.0 1.6e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 AIM20691.1 - 0.0025 16.4 0.0 0.0041 15.7 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 AIM20691.1 - 0.022 14.1 0.6 0.03 13.6 0.6 1.1 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family TauD PF02668.16 AIM20693.1 - 3.8e-41 141.7 0.3 4.2e-41 141.5 0.3 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family AMP-binding PF00501.28 AIM20694.1 - 3e-79 266.6 0.0 4.1e-79 266.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 AIM20694.1 - 2.3e-26 92.5 0.0 4.3e-25 88.3 0.0 2.3 1 1 0 1 1 1 1 Condensation domain AMP-binding_C PF13193.6 AIM20694.1 - 3.9e-10 40.6 0.0 1.1e-09 39.2 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 AIM20694.1 - 8.7e-10 38.8 0.1 2.8e-09 37.2 0.1 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site HD_4 PF13328.6 AIM20695.1 - 0.0036 17.0 0.0 0.0048 16.6 0.0 1.2 1 0 0 1 1 1 1 HD domain AMP-binding PF00501.28 AIM20696.1 - 1.5e-86 290.6 0.0 2e-86 290.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 AIM20696.1 - 9.5e-23 80.6 0.0 1.3e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 Condensation domain AMP-binding_C PF13193.6 AIM20696.1 - 9.1e-12 45.8 0.0 2e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 AIM20696.1 - 1.4e-11 44.5 0.0 3.6e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Cas_csx3 PF09620.10 AIM20696.1 - 0.097 12.6 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_csx3) AMP-binding PF00501.28 AIM20697.1 - 6.5e-76 255.6 0.0 8.9e-76 255.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 AIM20697.1 - 2.2e-27 95.9 0.0 3.3e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Condensation domain AMP-binding_C PF13193.6 AIM20697.1 - 1.5e-10 41.9 0.0 3.3e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 AIM20697.1 - 6.8e-09 36.0 0.1 1.4e-08 34.9 0.1 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Condensation PF00668.20 AIM20698.1 - 1e-115 387.0 0.0 2.4e-74 250.6 0.0 2.5 2 0 0 2 2 2 2 Condensation domain AMP-binding PF00501.28 AIM20698.1 - 1.1e-93 314.1 0.0 1.7e-93 313.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 AIM20698.1 - 2.4e-66 223.9 0.0 4.9e-66 222.9 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 AIM20698.1 - 1.8e-48 165.7 0.0 4e-48 164.6 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 AIM20698.1 - 1.5e-39 134.6 2.6 1.9e-39 134.3 1.2 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 AIM20698.1 - 8.7e-22 77.3 0.0 6.8e-11 42.4 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 AIM20698.1 - 2.1e-19 70.0 0.0 5.3e-19 68.7 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension AMP-binding_C PF13193.6 AIM20698.1 - 7.5e-09 36.5 0.0 2.3e-08 34.9 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Thiolase_N PF00108.23 AIM20698.1 - 2.1e-05 24.0 0.1 3.9e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Transferase PF02458.15 AIM20698.1 - 0.0087 14.8 0.0 0.02 13.6 0.0 1.5 1 0 0 1 1 1 1 Transferase family Thioesterase PF00975.20 AIM20699.1 - 6.3e-20 72.3 0.0 7e-20 72.1 0.0 1.0 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 AIM20699.1 - 1.4e-05 25.9 1.2 4.2e-05 24.3 1.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AIM20699.1 - 3.1e-05 23.4 0.1 0.0071 15.6 0.1 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 AIM20699.1 - 0.00065 19.4 0.0 0.0011 18.7 0.0 1.3 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 AIM20699.1 - 0.002 17.8 0.2 0.54 9.8 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 AIM20699.1 - 0.0073 16.2 0.0 0.0095 15.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 AIM20699.1 - 0.013 15.1 0.1 0.65 9.5 0.1 2.1 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 AIM20699.1 - 0.035 13.6 0.0 3 7.3 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family MFS_1 PF07690.16 AIM20700.1 - 2.4e-39 135.3 47.9 3e-39 135.0 47.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 AIM20700.1 - 2.2e-08 33.1 30.3 7.3e-07 28.1 12.5 2.5 2 1 1 3 3 3 2 MFS/sugar transport protein Sugar_tr PF00083.24 AIM20700.1 - 1.1e-06 27.8 6.0 1.1e-06 27.8 6.0 3.4 2 2 1 3 3 3 2 Sugar (and other) transporter FMN_red PF03358.15 AIM20701.1 - 4.6e-11 42.7 0.1 1.6e-10 41.0 0.1 1.9 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_5 PF12724.7 AIM20701.1 - 4e-07 30.4 0.0 6.7e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_1 PF00258.25 AIM20701.1 - 1.4e-06 28.5 0.0 1.5e-06 28.4 0.0 1.3 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.17 AIM20701.1 - 1.9e-06 27.7 0.0 2.7e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_3 PF12641.7 AIM20701.1 - 0.14 11.8 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin domain GGDEF PF00990.21 AIM20702.1 - 2.3e-43 147.7 1.5 3.4e-43 147.2 1.5 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain MASE1 PF05231.14 AIM20702.1 - 0.00047 19.4 36.8 0.00073 18.8 36.8 1.3 1 0 0 1 1 1 1 MASE1 MHYT PF03707.16 AIM20702.1 - 0.14 12.3 0.2 0.14 12.3 0.2 3.8 5 0 0 5 5 5 0 Bacterial signalling protein N terminal repeat Phage_P2_GpU PF06995.11 AIM20702.1 - 0.17 11.5 0.1 0.3 10.7 0.1 1.3 1 0 0 1 1 1 0 Phage P2 GpU CSD PF00313.22 AIM20703.1 - 2.2e-11 43.4 0.2 3.6e-11 42.7 0.2 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain DUF3226 PF11536.8 AIM20703.1 - 0.017 14.8 0.2 0.023 14.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3226) FIT1_2 PF17357.2 AIM20703.1 - 0.04 14.0 1.1 0.22 11.7 0.1 2.0 2 0 0 2 2 2 0 Facilitor Of iron transport 1 and 2 DUF1802 PF08819.11 AIM20703.1 - 0.074 12.9 0.0 0.11 12.3 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1802) Glyoxalase PF00903.25 AIM20704.1 - 1.1e-13 51.5 0.1 1.6e-13 50.9 0.1 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 AIM20704.1 - 2.6e-05 24.4 0.1 3.8e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 AIM20704.1 - 0.00032 21.5 0.2 0.00053 20.7 0.2 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 AIM20704.1 - 0.0089 16.2 0.1 0.048 13.8 0.1 2.1 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 AIM20704.1 - 0.065 13.2 0.0 0.37 10.7 0.0 1.9 2 0 0 2 2 2 0 Glyoxalase-like domain ABC_tran PF00005.27 AIM20705.1 - 4e-36 124.6 0.0 5.2e-36 124.2 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIM20705.1 - 1.6e-16 61.0 0.2 5.2e-08 33.0 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIM20705.1 - 3.4e-09 36.5 0.0 0.0012 18.3 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 AIM20705.1 - 1.9e-06 27.0 0.3 0.02 13.7 0.1 3.0 2 1 0 2 2 2 2 Predicted ATPase of the ABC class AAA_23 PF13476.6 AIM20705.1 - 3.5e-06 27.7 0.1 6.5e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AIM20705.1 - 4.5e-06 26.3 0.1 1e-05 25.2 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AIM20705.1 - 0.00012 22.5 0.1 0.00021 21.8 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.6 AIM20705.1 - 0.00014 21.7 0.0 0.00092 19.0 0.0 1.8 1 1 1 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 AIM20705.1 - 0.00016 21.6 0.0 0.00028 20.8 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 AIM20705.1 - 0.00065 20.0 0.1 0.0038 17.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 AIM20705.1 - 0.0018 18.3 0.0 0.0028 17.6 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_33 PF13671.6 AIM20705.1 - 0.0019 18.4 0.0 0.0029 17.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 AIM20705.1 - 0.002 18.2 0.2 0.031 14.4 0.2 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Adeno_IVa2 PF02456.15 AIM20705.1 - 0.0023 16.8 0.0 0.0037 16.1 0.0 1.2 1 0 0 1 1 1 1 Adenovirus IVa2 protein AAA_30 PF13604.6 AIM20705.1 - 0.0025 17.6 0.1 0.0087 15.8 0.0 1.9 2 1 1 3 3 3 1 AAA domain AAA_13 PF13166.6 AIM20705.1 - 0.003 16.3 0.0 1.2 7.7 0.0 2.1 2 0 0 2 2 2 2 AAA domain AAA_27 PF13514.6 AIM20705.1 - 0.0087 15.7 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 AIM20705.1 - 0.014 15.0 0.1 0.056 13.0 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.6 AIM20705.1 - 0.015 15.5 0.1 2.3 8.5 0.1 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 AIM20705.1 - 0.019 15.5 0.0 0.038 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 AIM20705.1 - 0.019 15.4 0.0 2.6 8.5 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 AIM20705.1 - 0.025 14.5 0.0 0.063 13.2 0.0 1.6 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.6 AIM20705.1 - 0.036 14.1 0.0 0.16 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 AIM20705.1 - 0.04 14.2 0.0 0.2 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 AIM20705.1 - 0.051 12.9 0.0 0.079 12.2 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin APS_kinase PF01583.20 AIM20705.1 - 0.072 13.0 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_24 PF13479.6 AIM20705.1 - 0.093 12.4 0.1 0.27 10.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 AIM20705.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Rad17 PF03215.15 AIM20705.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain BPD_transp_1 PF00528.22 AIM20706.1 - 3e-14 53.2 20.2 3e-14 53.2 20.2 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component Acetyltransf_1 PF00583.25 AIM20707.1 - 3.1e-10 40.3 0.1 4.9e-10 39.7 0.1 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AIM20707.1 - 2.3e-06 28.0 0.1 3.2e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AIM20707.1 - 2.5e-06 27.4 0.0 3.2e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 AIM20707.1 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase FR47 PF08445.10 AIM20707.1 - 0.016 15.2 0.0 0.023 14.7 0.0 1.2 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.6 AIM20707.1 - 0.17 12.1 0.0 0.23 11.6 0.0 1.2 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase SBP_bac_3 PF00497.20 AIM20708.1 - 2.1e-36 125.5 0.2 2.6e-36 125.2 0.2 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 AIM20708.1 - 0.062 13.5 0.0 0.17 12.1 0.0 1.8 1 1 0 1 1 1 0 Ligated ion channel L-glutamate- and glycine-binding site Bac_luciferase PF00296.20 AIM20709.1 - 4.6e-64 216.8 0.2 8.9e-64 215.9 0.2 1.4 1 1 1 2 2 2 1 Luciferase-like monooxygenase Peptidase_M20 PF01546.28 AIM20710.1 - 5.4e-30 104.6 0.4 6.9e-30 104.3 0.4 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AIM20710.1 - 1.7e-11 44.0 0.0 3.5e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 AIM20710.1 - 0.086 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 CSD PF00313.22 AIM20711.1 - 2.8e-33 113.6 0.6 3e-33 113.5 0.6 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 AIM20711.1 - 2.8e-05 23.7 0.4 5.5e-05 22.8 0.4 1.5 1 1 0 1 1 1 1 Ribonuclease B OB domain MFS_1 PF07690.16 AIM20712.1 - 5.6e-45 153.8 45.8 5.6e-45 153.8 45.8 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 AIM20712.1 - 4.1e-06 25.9 7.3 4.1e-06 25.9 7.3 2.4 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 AIM20712.1 - 0.0018 17.7 37.2 0.003 16.9 37.2 1.4 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB DUF63 PF01889.17 AIM20712.1 - 1.5 9.0 5.8 0.55 10.4 0.3 2.6 1 1 0 2 2 2 0 Membrane protein of unknown function DUF63 TetR_N PF00440.23 AIM20713.1 - 7.7e-15 54.4 1.7 6.4e-14 51.5 0.6 2.8 3 0 0 3 3 3 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.6 AIM20713.1 - 5.9e-09 36.2 1.5 1.1e-08 35.3 1.5 1.4 1 0 0 1 1 1 1 BetI-type transcriptional repressor, C-terminal TetR_C_31 PF17940.1 AIM20713.1 - 0.00097 19.3 2.6 0.002 18.3 1.4 1.9 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain HTH_32 PF13565.6 AIM20713.1 - 0.0017 18.9 0.1 0.2 12.3 0.0 2.5 3 0 0 3 3 3 1 Homeodomain-like domain TetR_C_30 PF17939.1 AIM20713.1 - 0.0043 17.3 0.3 0.01 16.1 0.2 1.7 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain CRCB PF02537.15 AIM20714.1 - 9.6e-25 86.7 10.9 1.2e-24 86.4 10.9 1.1 1 0 0 1 1 1 1 CrcB-like protein, Camphor Resistance (CrcB) MgtE PF01769.16 AIM20714.1 - 0.11 12.8 0.2 0.11 12.8 0.2 2.3 1 1 1 2 2 2 0 Divalent cation transporter Phage_holin_3_1 PF05106.12 AIM20714.1 - 0.31 11.5 2.8 0.2 12.1 0.5 2.1 1 1 1 2 2 2 0 Phage holin family (Lysis protein S) DUF4199 PF13858.6 AIM20714.1 - 0.83 10.0 11.5 0.4 11.1 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) Acetyltransf_10 PF13673.7 AIM20715.1 - 0.0035 17.3 0.0 0.0053 16.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GGDEF PF00990.21 AIM20716.1 - 1.8e-44 151.3 0.1 2.4e-44 151.0 0.1 1.1 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain MASE2 PF05230.11 AIM20716.1 - 1.4e-30 105.2 9.2 8.4e-30 102.7 5.0 2.3 2 0 0 2 2 2 2 MASE2 domain GGDEF_2 PF17853.1 AIM20716.1 - 0.0015 18.8 0.1 0.0027 17.9 0.1 1.5 1 0 0 1 1 1 1 GGDEF-like domain MttA_Hcf106 PF02416.16 AIM20717.1 - 5.6e-12 44.8 1.0 6.5e-12 44.6 1.0 1.2 1 1 0 1 1 1 1 mttA/Hcf106 family Radical_SAM PF04055.21 AIM20718.1 - 1.3e-15 58.1 0.0 2.1e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily LIAS_N PF16881.5 AIM20718.1 - 1.3e-07 32.0 0.1 7.2e-07 29.6 0.1 2.0 2 0 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family BPL_LplA_LipB PF03099.19 AIM20719.1 - 1.2e-06 28.4 0.1 2.4e-06 27.5 0.1 1.4 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF493 PF04359.14 AIM20720.1 - 8.2e-31 106.4 0.0 9.2e-31 106.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF493) NRho PF16733.5 AIM20720.1 - 0.067 13.3 0.1 1.8 8.7 0.1 2.2 2 0 0 2 2 2 0 Rhomboid N-terminal domain DrsE_2 PF13686.6 AIM20720.1 - 0.15 12.0 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 DsrE/DsrF/DrsH-like family Peptidase_S11 PF00768.20 AIM20721.1 - 6.6e-100 333.5 0.1 8.6e-100 333.1 0.1 1.1 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase PBP5_C PF07943.13 AIM20721.1 - 5.1e-25 87.5 0.0 8.8e-25 86.8 0.0 1.4 1 0 0 1 1 1 1 Penicillin-binding protein 5, C-terminal domain Beta-lactamase2 PF13354.6 AIM20721.1 - 2.1e-07 30.7 0.0 2.9e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase enzyme family Beta-lactamase PF00144.24 AIM20721.1 - 0.00057 19.2 0.2 0.012 14.9 0.0 2.2 1 1 1 2 2 2 1 Beta-lactamase DPBB_1 PF03330.18 AIM20722.1 - 2.9e-24 85.1 0.0 7.3e-24 83.9 0.0 1.7 2 0 0 2 2 2 1 Lytic transglycolase SPOR PF05036.13 AIM20722.1 - 3.1e-17 62.7 4.9 6.9e-17 61.6 4.9 1.6 1 0 0 1 1 1 1 Sporulation related domain FTSW_RODA_SPOVE PF01098.19 AIM20723.1 - 7.2e-123 410.1 29.3 8.8e-123 409.8 29.3 1.0 1 0 0 1 1 1 1 Cell cycle protein Transpeptidase PF00905.22 AIM20724.1 - 6.5e-87 291.6 1.0 1.1e-86 290.9 0.3 1.6 2 0 0 2 2 2 1 Penicillin binding protein transpeptidase domain PBP_dimer PF03717.15 AIM20724.1 - 1.8e-45 155.5 0.2 3e-45 154.7 0.2 1.4 1 0 0 1 1 1 1 Penicillin-binding Protein dimerisation domain SPOUT_MTase PF02590.17 AIM20725.1 - 5.4e-47 159.6 0.0 6e-47 159.5 0.0 1.0 1 0 0 1 1 1 1 Predicted SPOUT methyltransferase RsfS PF02410.15 AIM20726.1 - 6e-28 97.2 0.3 6.8e-28 97.0 0.3 1.0 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation CTP_transf_like PF01467.26 AIM20727.1 - 1.2e-33 116.3 0.0 1.4e-33 116.1 0.0 1.0 1 0 0 1 1 1 1 Cytidylyltransferase-like DNA_pol3_delt_C PF14840.6 AIM20728.1 - 1.7e-65 219.0 8.8 1.7e-65 219.0 8.8 1.9 2 0 0 2 2 2 1 Processivity clamp loader gamma complex DNA pol III C-term DNA_pol3_delta PF06144.13 AIM20728.1 - 3.7e-42 144.1 0.3 1.5e-41 142.0 0.0 1.9 2 0 0 2 2 2 1 DNA polymerase III, delta subunit LptE PF04390.12 AIM20729.1 - 1e-16 61.5 0.3 1.6e-16 60.9 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide-assembly tRNA-synt_1_2 PF13603.6 AIM20730.1 - 1.3e-78 262.7 0.0 2.3e-78 262.0 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1 PF00133.22 AIM20730.1 - 3.6e-71 240.2 9.6 3.2e-26 91.8 0.4 6.0 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 AIM20730.1 - 5.8e-32 110.9 0.0 3.4e-22 78.7 0.0 4.0 3 1 1 4 4 4 4 tRNA synthetases class I (M) Anticodon_1 PF08264.13 AIM20730.1 - 1.3e-17 64.2 0.0 2.4e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1f PF01921.18 AIM20730.1 - 1.4e-05 24.2 0.0 0.14 11.0 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (K) tRNA-synt_1e PF01406.19 AIM20730.1 - 3.2e-05 23.4 0.0 0.087 12.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain DUF1451 PF07295.11 AIM20731.1 - 8.3e-56 188.1 0.5 9.5e-56 187.9 0.5 1.0 1 0 0 1 1 1 1 Zinc-ribbon containing domain TniQ PF06527.11 AIM20731.1 - 0.0059 17.3 0.9 0.014 16.1 0.9 1.6 1 1 0 1 1 1 1 TniQ SRI PF08236.11 AIM20731.1 - 0.013 15.6 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain EH_Signature PF15611.6 AIM20731.1 - 0.017 14.6 1.0 0.02 14.3 1.0 1.0 1 0 0 1 1 1 0 EH_Signature domain Baculo_PEP_C PF04513.12 AIM20731.1 - 0.02 15.0 0.2 0.034 14.2 0.2 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ADK_lid PF05191.14 AIM20731.1 - 0.023 14.7 1.6 0.049 13.6 1.6 1.5 1 0 0 1 1 1 0 Adenylate kinase, active site lid GrpE PF01025.19 AIM20731.1 - 0.025 14.2 0.9 0.03 14.0 0.9 1.1 1 0 0 1 1 1 0 GrpE KxDL PF10241.9 AIM20731.1 - 0.057 13.7 0.3 0.11 12.8 0.3 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein VbhA PF18495.1 AIM20731.1 - 0.094 12.6 3.2 0.34 10.8 0.3 2.4 2 0 0 2 2 2 0 Antitoxin VbhA Apolipoprotein PF01442.18 AIM20731.1 - 0.12 12.3 7.8 0.18 11.7 7.8 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain HypA PF01155.19 AIM20731.1 - 0.15 12.1 0.2 0.28 11.2 0.1 1.7 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_10 PF10058.9 AIM20731.1 - 0.18 11.6 1.9 0.48 10.2 1.9 1.7 1 1 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein PhnA_Zn_Ribbon PF08274.12 AIM20731.1 - 0.18 11.8 3.1 8 6.5 0.1 2.3 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Tweety PF04906.13 AIM20731.1 - 0.19 10.4 0.1 0.23 10.1 0.1 1.1 1 0 0 1 1 1 0 Tweety zinc_ribbon_2 PF13240.6 AIM20731.1 - 0.23 11.2 2.1 1.5 8.6 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 AIM20731.1 - 0.28 11.3 2.3 0.78 9.9 2.3 1.8 1 1 0 1 1 1 0 Zinc ribbon domain DUF883 PF05957.13 AIM20731.1 - 0.43 11.2 4.4 0.6 10.8 4.0 1.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Flavodoxin_2 PF02525.17 AIM20732.1 - 7e-38 130.3 0.0 7.9e-38 130.2 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 AIM20732.1 - 1.1e-06 28.4 0.0 1.4e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase IU_nuc_hydro PF01156.19 AIM20733.1 - 1.8e-91 306.9 0.2 2.1e-91 306.7 0.2 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase ABC_tran PF00005.27 AIM20734.1 - 8.5e-34 117.0 0.0 1.2e-33 116.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIM20734.1 - 5e-09 36.4 0.1 0.00095 19.1 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIM20734.1 - 1.5e-07 31.1 0.2 7.2e-07 28.9 0.2 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 AIM20734.1 - 6.9e-05 22.9 0.0 9.1e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 AIM20734.1 - 9.6e-05 22.7 0.2 0.00019 21.7 0.2 1.8 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AIM20734.1 - 0.00012 22.0 0.1 0.00023 21.1 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 AIM20734.1 - 0.0002 21.0 0.1 0.00041 20.0 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AIM20734.1 - 0.00042 20.7 0.1 0.00058 20.3 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 AIM20734.1 - 0.00087 19.5 0.1 0.0016 18.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 AIM20734.1 - 0.0097 15.3 0.2 0.019 14.3 0.0 1.5 2 0 0 2 2 2 1 KaiC AAA_15 PF13175.6 AIM20734.1 - 0.01 15.6 0.0 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain ATPase_2 PF01637.18 AIM20734.1 - 0.011 15.7 0.8 0.05 13.5 0.1 2.2 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 AIM20734.1 - 0.015 15.0 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DLIC PF05783.11 AIM20734.1 - 0.016 14.1 0.1 0.022 13.6 0.1 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_30 PF13604.6 AIM20734.1 - 0.018 14.8 0.2 0.041 13.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 AIM20734.1 - 0.019 14.6 0.6 0.037 13.6 0.1 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 AIM20734.1 - 0.02 15.4 0.0 0.042 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AIM20734.1 - 0.021 15.4 0.3 0.044 14.3 0.3 1.6 1 1 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 AIM20734.1 - 0.024 13.4 2.5 4.5 6.0 0.2 3.0 2 1 0 2 2 2 0 Predicted ATPase of the ABC class Septin PF00735.18 AIM20734.1 - 0.034 13.4 0.1 0.062 12.6 0.0 1.5 2 0 0 2 2 2 0 Septin AAA_24 PF13479.6 AIM20734.1 - 0.034 13.9 0.3 0.1 12.3 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 AIM20734.1 - 0.04 12.6 0.1 0.25 9.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain S4 PF01479.25 AIM20734.1 - 0.048 13.4 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 S4 domain SbcCD_C PF13558.6 AIM20734.1 - 0.054 13.7 0.9 3 8.1 0.5 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 AIM20734.1 - 0.054 13.9 0.1 0.19 12.1 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 AIM20734.1 - 0.064 12.8 0.1 0.099 12.2 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region T2SSE PF00437.20 AIM20734.1 - 0.069 12.2 0.8 0.09 11.8 0.1 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein ATP_bind_1 PF03029.17 AIM20734.1 - 0.078 12.7 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 AIM20734.1 - 0.098 12.7 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Dynamin family Zeta_toxin PF06414.12 AIM20734.1 - 0.11 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Viral_helicase1 PF01443.18 AIM20734.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.5 2 0 0 2 2 1 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 AIM20734.1 - 0.18 11.3 1.0 0.33 10.5 0.2 1.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 AIM20734.1 - 0.21 12.0 2.3 1.1 9.7 0.3 2.6 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) BPD_transp_1 PF00528.22 AIM20735.1 - 2.3e-18 66.6 18.3 2.3e-18 66.6 18.3 1.3 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 AIM20736.1 - 1.8e-24 86.5 5.9 1.8e-24 86.5 5.9 1.5 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component DUF2839 PF10999.8 AIM20736.1 - 2.7 8.4 5.5 52 4.3 4.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) SBP_bac_3 PF00497.20 AIM20737.1 - 8.8e-49 165.9 0.5 1.1e-48 165.7 0.5 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1 PF09084.11 AIM20737.1 - 3.5e-05 23.8 0.3 0.00031 20.8 0.1 2.0 1 1 1 2 2 2 1 NMT1/THI5 like Phosphonate-bd PF12974.7 AIM20737.1 - 0.00021 21.0 0.0 0.00035 20.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein DUF3991 PF13154.6 AIM20737.1 - 0.0096 16.3 0.1 1.5 9.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3991) GerD PF17898.1 AIM20737.1 - 0.25 11.3 2.3 18 5.3 0.4 2.5 2 0 0 2 2 2 0 Spore germination GerD central core domain CN_hydrolase PF00795.22 AIM20738.1 - 1.1e-39 136.3 0.0 1.5e-39 135.9 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase TruB_C PF09142.11 AIM20738.1 - 0.0011 18.7 0.0 0.0026 17.5 0.0 1.6 1 0 0 1 1 1 1 tRNA Pseudouridine synthase II, C terminal PepSY_TM_like_2 PF16357.5 AIM20738.1 - 0.018 15.0 0.7 0.35 10.8 0.6 2.3 1 1 0 1 1 1 0 Putative PepSY_TM-like CorC_HlyC PF03471.17 AIM20739.1 - 1.5e-22 79.4 0.4 5.3e-22 77.6 0.0 2.1 2 0 0 2 2 2 1 Transporter associated domain CBS PF00571.28 AIM20739.1 - 1.7e-15 57.1 3.8 1.8e-08 34.7 0.2 2.9 3 0 0 3 3 3 2 CBS domain UPF0054 PF02130.17 AIM20740.1 - 1e-39 135.3 0.0 1.2e-39 135.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 PhoH PF02562.16 AIM20741.1 - 8.5e-95 316.0 0.0 1.1e-94 315.6 0.0 1.2 1 0 0 1 1 1 1 PhoH-like protein AAA_30 PF13604.6 AIM20741.1 - 2.9e-09 36.9 0.0 5.4e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 AIM20741.1 - 5.5e-05 23.5 0.1 0.00024 21.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 AIM20741.1 - 0.0015 18.3 0.0 0.0039 17.0 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase IstB_IS21 PF01695.17 AIM20741.1 - 0.0019 17.9 0.0 0.0051 16.6 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.6 AIM20741.1 - 0.0079 16.5 0.0 0.022 15.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 AIM20741.1 - 0.029 14.0 0.0 0.061 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zot PF05707.12 AIM20741.1 - 0.07 12.8 0.0 7.2 6.2 0.0 2.3 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) PhnA PF03831.14 AIM20742.1 - 8.5e-35 118.5 4.6 1e-34 118.2 4.6 1.1 1 0 0 1 1 1 1 PhnA domain PhnA_Zn_Ribbon PF08274.12 AIM20742.1 - 8.8e-18 64.0 5.9 1.4e-17 63.3 5.9 1.3 1 0 0 1 1 1 1 PhnA Zinc-Ribbon TF_Zn_Ribbon PF08271.12 AIM20742.1 - 0.00057 19.4 1.3 0.00069 19.1 0.3 1.7 2 0 0 2 2 2 1 TFIIB zinc-binding A2L_zn_ribbon PF08792.10 AIM20742.1 - 0.013 15.2 0.6 0.024 14.3 0.6 1.4 1 0 0 1 1 1 0 A2L zinc ribbon domain PADR1 PF08063.12 AIM20742.1 - 0.022 14.5 1.7 0.044 13.6 1.7 1.5 1 0 0 1 1 1 0 PADR1 (NUC008) domain zinc-ribbons_6 PF07191.12 AIM20742.1 - 0.032 14.2 1.0 0.052 13.5 1.0 1.3 1 0 0 1 1 1 0 zinc-ribbons zinc_ribbon_2 PF13240.6 AIM20742.1 - 0.042 13.6 4.3 0.14 11.9 4.3 1.9 1 1 0 1 1 1 0 zinc-ribbon domain zf-HYPF PF07503.12 AIM20742.1 - 0.046 13.5 2.2 6.2 6.7 0.1 2.3 2 0 0 2 2 2 0 HypF finger zf-RRN7 PF11781.8 AIM20742.1 - 0.075 12.7 2.2 0.16 11.7 2.2 1.6 1 1 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 OrfB_Zn_ribbon PF07282.11 AIM20742.1 - 0.11 12.4 0.9 0.2 11.6 0.9 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Herpes_UL31 PF02718.14 AIM20742.1 - 0.13 11.2 0.2 0.18 10.7 0.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL31-like protein TFIIS_C PF01096.18 AIM20742.1 - 0.15 12.0 3.8 4.3 7.3 0.1 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) DUF4379 PF14311.6 AIM20742.1 - 0.15 12.4 3.5 0.29 11.5 0.2 2.2 1 1 1 2 2 2 0 Probable Zinc-ribbon domain HypA PF01155.19 AIM20742.1 - 0.18 11.8 0.8 0.25 11.4 0.3 1.5 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_Tnp_IS1595 PF12760.7 AIM20742.1 - 0.2 11.7 3.7 0.61 10.1 3.9 1.7 1 1 1 2 2 2 0 Transposase zinc-ribbon domain UPF0547 PF10571.9 AIM20742.1 - 1.4 9.1 6.2 1.1 9.4 0.3 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Zn-ribbon_8 PF09723.10 AIM20742.1 - 1.7 8.9 5.0 12 6.1 0.9 2.2 1 1 2 3 3 3 0 Zinc ribbon domain zf-TFIIB PF13453.6 AIM20742.1 - 2.9 7.3 5.8 26 4.2 6.2 2.1 1 1 1 2 2 2 0 Transcription factor zinc-finger zinc_ribbon_4 PF13717.6 AIM20742.1 - 3.1 7.8 8.2 21 5.1 5.8 2.6 2 1 0 2 2 2 0 zinc-ribbon domain UPF0004 PF00919.20 AIM20743.1 - 3.9e-28 97.4 0.0 7.5e-28 96.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 AIM20743.1 - 3.6e-26 92.5 0.0 5.6e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily TRAM PF01938.20 AIM20743.1 - 1.9e-17 63.0 0.1 4.6e-17 61.8 0.2 1.7 2 0 0 2 2 2 1 TRAM domain B12-binding PF02310.19 AIM20743.1 - 0.00052 20.0 0.1 0.016 15.2 0.0 3.1 4 0 0 4 4 4 1 B12 binding domain TRAM_2 PF18693.1 AIM20743.1 - 0.046 13.9 0.3 0.13 12.5 0.3 1.8 1 1 0 1 1 1 0 TRAM domain FAD_binding_3 PF01494.19 AIM20744.1 - 2.4e-26 92.8 0.0 5.3e-26 91.7 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 AIM20744.1 - 7.1e-07 29.1 2.7 8.4e-06 25.6 0.3 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 AIM20744.1 - 8.4e-05 21.8 0.3 0.00024 20.3 0.8 1.4 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 AIM20744.1 - 0.00024 20.6 4.3 0.0019 17.7 4.3 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AIM20744.1 - 0.00037 19.7 2.0 0.00037 19.7 2.0 1.5 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 AIM20744.1 - 0.00049 20.3 0.5 0.0014 18.9 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AIM20744.1 - 0.00087 18.6 0.1 0.0038 16.5 0.2 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 AIM20744.1 - 0.0019 17.3 0.0 0.0046 16.1 0.0 1.6 2 0 0 2 2 2 1 Squalene epoxidase Lycopene_cycl PF05834.12 AIM20744.1 - 0.0019 17.3 3.1 0.0064 15.6 2.2 2.1 2 1 0 2 2 2 1 Lycopene cyclase protein Trp_halogenase PF04820.14 AIM20744.1 - 0.0067 15.3 4.1 0.37 9.6 0.0 2.7 2 1 0 2 2 2 1 Tryptophan halogenase HI0933_like PF03486.14 AIM20744.1 - 0.011 14.5 2.6 0.12 11.0 1.4 2.1 2 0 0 2 2 2 0 HI0933-like protein 3HCDH_N PF02737.18 AIM20744.1 - 0.042 13.7 0.1 0.068 13.1 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 AIM20744.1 - 0.07 12.4 0.0 0.41 9.8 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PC_rep PF01851.22 AIM20744.1 - 0.098 13.1 0.3 0.33 11.5 0.1 2.0 2 0 0 2 2 2 0 Proteasome/cyclosome repeat Pyr_redox PF00070.27 AIM20744.1 - 0.19 12.3 0.2 0.43 11.2 0.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Asn_synthase PF00733.21 AIM20745.1 - 1.3e-103 347.4 0.4 2.9e-59 201.5 0.2 2.4 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 AIM20745.1 - 1.7e-42 144.2 0.0 2.9e-42 143.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 AIM20745.1 - 2.3e-37 128.2 0.1 7.6e-37 126.5 0.1 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 AIM20745.1 - 3.3e-08 33.2 0.0 6.2e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 AIM20745.1 - 0.054 12.6 0.0 0.089 11.9 0.0 1.4 1 0 0 1 1 1 0 NAD synthase tRNA_Me_trans PF03054.16 AIM20745.1 - 0.075 11.8 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase Stealth_CR4 PF17103.5 AIM20745.1 - 0.16 11.8 0.0 31 4.6 0.1 2.4 2 0 0 2 2 2 0 Stealth protein CR4, conserved region 4 Glyco_hydro_18 PF00704.28 AIM20746.1 - 4.3e-30 105.5 6.2 1.5e-29 103.8 6.2 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 fn3 PF00041.21 AIM20746.1 - 2.4e-05 24.6 0.1 0.00015 22.1 0.1 2.3 1 1 0 1 1 1 1 Fibronectin type III domain Hydrolase_6 PF13344.6 AIM20747.1 - 1.1e-23 83.3 0.0 3.3e-23 81.7 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AIM20747.1 - 3.7e-21 74.9 0.0 1e-20 73.5 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 AIM20747.1 - 1.7e-13 51.4 0.1 3.3e-11 43.9 0.1 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 AIM20747.1 - 5.6e-12 46.1 0.0 3.2e-09 37.1 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AIM20747.1 - 0.18 11.5 0.0 0.83 9.3 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase ROK PF00480.20 AIM20748.1 - 7.5e-91 304.6 0.3 9.5e-91 304.3 0.3 1.1 1 0 0 1 1 1 1 ROK family MarR PF01047.22 AIM20748.1 - 2.3e-07 30.6 0.0 6.4e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 AIM20748.1 - 0.00018 21.0 0.6 0.00087 18.8 0.3 2.2 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Fe_dep_repress PF01325.19 AIM20748.1 - 0.00024 21.2 0.0 0.00067 19.8 0.0 1.8 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain MarR_2 PF12802.7 AIM20748.1 - 0.0005 19.9 1.7 0.00095 19.0 0.3 2.1 2 0 0 2 2 2 1 MarR family HTH_Crp_2 PF13545.6 AIM20748.1 - 0.0036 17.3 0.1 0.0084 16.1 0.1 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain SMC_ScpB PF04079.16 AIM20748.1 - 0.0087 15.7 0.2 0.018 14.7 0.2 1.5 1 0 0 1 1 1 1 Segregation and condensation complex subunit ScpB HTH_IclR PF09339.10 AIM20748.1 - 0.047 13.5 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_7 PF02796.15 AIM20748.1 - 0.18 11.9 0.1 11 6.2 0.1 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase Amidohydro_1 PF01979.20 AIM20749.1 - 3.3e-43 148.3 0.7 3.8e-43 148.1 0.7 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AIM20749.1 - 1.7e-08 34.4 1.2 5.8e-07 29.3 0.1 2.4 2 0 0 2 2 2 2 Amidohydrolase family Glucosamine_iso PF01182.20 AIM20750.1 - 1e-20 74.6 0.0 1.7e-20 73.9 0.0 1.4 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase PTS_EIIC PF02378.18 AIM20751.1 - 1.9e-78 263.7 34.0 1.9e-78 263.7 34.0 2.0 2 0 0 2 2 2 1 Phosphotransferase system, EIIC PTS_EIIA_1 PF00358.20 AIM20751.1 - 7.1e-49 164.8 0.3 1.4e-48 163.9 0.3 1.5 1 0 0 1 1 1 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 PTS_EIIB PF00367.20 AIM20751.1 - 8.5e-12 44.4 0.6 1.6e-11 43.5 0.6 1.5 1 0 0 1 1 1 1 phosphotransferase system, EIIB Biotin_lipoyl_2 PF13533.6 AIM20751.1 - 0.0029 17.4 0.1 0.014 15.2 0.0 2.1 2 0 0 2 2 2 1 Biotin-lipoyl like Peptidase_M23 PF01551.22 AIM20751.1 - 0.0033 17.6 0.0 0.012 15.8 0.0 2.0 1 0 0 1 1 1 1 Peptidase family M23 Biotin_lipoyl PF00364.22 AIM20751.1 - 0.0049 16.7 0.1 0.55 10.1 0.0 2.8 2 1 0 2 2 2 1 Biotin-requiring enzyme RnfC_N PF13375.6 AIM20751.1 - 0.079 12.9 0.1 21 5.2 0.0 3.3 1 1 1 3 3 3 0 RnfC Barrel sandwich hybrid domain Ribosomal_60s PF00428.19 AIM20751.1 - 1.9 9.1 8.4 5.5 7.7 8.4 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein tRNA-synt_1c PF00749.21 AIM20752.1 - 5.3e-126 419.8 0.0 6.6e-126 419.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 AIM20752.1 - 1.1e-63 214.2 0.0 2.6e-63 213.0 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain OprD PF03573.13 AIM20753.1 - 1.8e-23 83.2 12.4 2.3e-23 82.9 12.4 1.0 1 0 0 1 1 1 1 outer membrane porin, OprD family YbfN PF13982.6 AIM20754.1 - 2.6e-41 139.8 1.8 3.3e-41 139.5 1.8 1.1 1 0 0 1 1 1 1 YbfN-like lipoprotein Peptidase_M13_N PF05649.13 AIM20754.1 - 0.002 17.9 0.1 0.0021 17.8 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M13 Hce2 PF14856.6 AIM20754.1 - 0.011 16.1 0.4 0.015 15.6 0.4 1.3 1 0 0 1 1 1 0 Pathogen effector; putative necrosis-inducing factor LPAM_1 PF08139.12 AIM20754.1 - 1.2 9.7 7.7 2.2 8.9 7.7 1.4 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Glyco_hydro_20 PF00728.22 AIM20755.1 - 1.2e-104 350.5 0.3 1.7e-104 350.0 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain CHB_HEX PF03173.13 AIM20755.1 - 2.4e-61 206.1 0.0 3.8e-61 205.4 0.0 1.3 1 0 0 1 1 1 1 Putative carbohydrate binding domain CHB_HEX_C PF03174.13 AIM20755.1 - 1.5e-32 111.4 0.1 4.2e-32 109.9 0.1 1.9 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain Glyco_hydro_20b PF02838.15 AIM20755.1 - 1.4e-15 58.2 0.0 3.4e-15 56.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 FUR PF01475.19 AIM20756.1 - 6.2e-48 161.9 0.4 7.2e-48 161.7 0.4 1.0 1 0 0 1 1 1 1 Ferric uptake regulator family PadR PF03551.14 AIM20756.1 - 0.0078 16.1 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_12 PF08461.10 AIM20756.1 - 0.015 15.3 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain SR1P PF13790.6 AIM20756.1 - 0.02 15.0 7.1 0.1 12.7 0.3 2.7 3 0 0 3 3 3 0 SR1 protein HTH_Tnp_Tc3_2 PF01498.18 AIM20756.1 - 0.12 12.6 0.0 1.9 8.8 0.0 2.2 1 1 1 2 2 2 0 Transposase Flavodoxin_1 PF00258.25 AIM20757.1 - 3.4e-23 82.4 0.1 4e-23 82.2 0.1 1.1 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_3 PF12641.7 AIM20757.1 - 0.042 13.5 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 Flavodoxin domain ssDBP_DBD PF18361.1 AIM20757.1 - 0.11 12.6 0.0 15 5.8 0.0 2.1 2 0 0 2 2 2 0 Single stranded DNA-binding protein ss DNA binding domain RHH_1 PF01402.21 AIM20758.1 - 5.8e-09 35.6 1.6 1.1e-08 34.7 1.6 1.5 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family RHH_3 PF12651.7 AIM20758.1 - 0.009 16.0 0.4 0.015 15.2 0.4 1.4 1 0 0 1 1 1 1 Ribbon-helix-helix domain Abhydrolase_1 PF00561.20 AIM20759.1 - 3.6e-24 85.8 0.1 8.5e-18 64.9 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AIM20759.1 - 1.4e-22 81.4 5.1 1.6e-22 81.2 5.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 AIM20759.1 - 2.5e-11 43.7 0.0 5.1e-09 36.2 0.0 2.2 1 1 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 AIM20759.1 - 3.2e-10 39.7 0.2 1.6e-09 37.4 0.2 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 AIM20759.1 - 1.1e-06 27.5 0.0 2.9e-06 26.2 0.0 1.6 1 1 0 1 1 1 1 Ndr family Thioesterase PF00975.20 AIM20759.1 - 2.1e-05 24.8 0.0 2.6e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain DUF676 PF05057.14 AIM20759.1 - 0.0043 16.6 0.0 0.0074 15.8 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Esterase PF00756.20 AIM20759.1 - 0.0093 15.6 0.0 0.016 14.8 0.0 1.6 1 1 0 1 1 1 1 Putative esterase Ser_hydrolase PF06821.13 AIM20759.1 - 0.012 15.5 0.4 0.033 14.1 0.1 1.8 2 0 0 2 2 2 0 Serine hydrolase Abhydrolase_4 PF08386.10 AIM20759.1 - 0.025 14.7 0.0 0.13 12.4 0.0 2.0 2 0 0 2 2 2 0 TAP-like protein Chlorophyllase PF07224.11 AIM20759.1 - 0.042 12.9 0.0 0.063 12.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase DUF915 PF06028.11 AIM20759.1 - 0.044 13.1 0.0 0.9 8.8 0.0 2.2 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Acyl_transf_1 PF00698.21 AIM20759.1 - 0.068 12.7 0.1 0.095 12.2 0.1 1.3 1 0 0 1 1 1 0 Acyl transferase domain DUF1057 PF06342.12 AIM20759.1 - 0.072 12.1 0.0 0.15 11.1 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) Lipase_3 PF01764.25 AIM20759.1 - 0.09 12.6 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) PAF-AH_p_II PF03403.13 AIM20759.1 - 0.097 11.2 0.0 0.14 10.6 0.0 1.3 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 AIM20759.1 - 0.11 11.4 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Palm_thioest PF02089.15 AIM20759.1 - 0.21 11.4 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase SeqA PF03925.13 AIM20760.1 - 5e-49 164.9 0.0 6.7e-49 164.5 0.0 1.2 1 0 0 1 1 1 1 SeqA protein C-terminal domain SeqA_N PF17206.3 AIM20760.1 - 4.3e-25 86.7 0.3 7.1e-25 86.0 0.3 1.4 1 0 0 1 1 1 1 SeqA protein N-terminal domain VAPB_antitox PF02697.14 AIM20760.1 - 0.13 13.1 0.0 0.28 12.0 0.0 1.6 1 1 0 1 1 1 0 Putative antitoxin PGM_PMM_I PF02878.16 AIM20761.1 - 1.2e-38 131.9 0.1 3.2e-38 130.5 0.1 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 AIM20761.1 - 3e-29 101.5 0.0 6.3e-29 100.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 AIM20761.1 - 3.7e-19 69.3 0.0 8.9e-19 68.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 AIM20761.1 - 4.8e-08 33.1 0.0 1.3e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PadR PF03551.14 AIM20762.1 - 9.1e-19 67.2 0.2 2.7e-18 65.7 0.1 1.8 2 0 0 2 2 2 1 Transcriptional regulator PadR-like family AphA_like PF14557.6 AIM20762.1 - 0.0057 16.4 0.0 0.011 15.5 0.0 1.6 1 1 0 1 1 1 1 Putative AphA-like transcriptional regulator FUR PF01475.19 AIM20762.1 - 0.22 11.7 0.0 0.22 11.7 0.0 2.2 2 0 0 2 2 2 0 Ferric uptake regulator family DUF3861 PF12977.7 AIM20763.1 - 2.2e-35 120.7 0.1 2.5e-35 120.5 0.1 1.0 1 0 0 1 1 1 1 Domain of Unknown Function with PDB structure (DUF3861) Big_1 PF02369.16 AIM20763.1 - 0.076 13.0 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) Peptidase_U32_C PF16325.5 AIM20763.1 - 0.11 12.8 0.0 0.19 12.0 0.0 1.5 1 1 0 1 1 1 0 Peptidase family U32 C-terminal domain Trans_reg_C PF00486.28 AIM20764.1 - 1.5e-21 76.3 0.0 3e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Response_reg PF00072.24 AIM20764.1 - 1.5e-21 76.7 0.0 2.1e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain KdpD PF02702.17 AIM20765.1 - 2.1e-99 331.2 0.1 5.2e-99 329.9 0.1 1.6 2 0 0 2 2 2 1 Osmosensitive K+ channel His kinase sensor domain DUF4118 PF13493.6 AIM20765.1 - 2.8e-30 104.2 10.4 2.8e-30 104.2 10.4 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4118) HATPase_c PF02518.26 AIM20765.1 - 3e-24 85.7 0.0 5.5e-24 84.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_3 PF13492.6 AIM20765.1 - 1.3e-12 48.2 0.0 3.5e-12 46.8 0.0 1.8 1 0 0 1 1 1 1 GAF domain HisKA PF00512.25 AIM20765.1 - 1.5e-10 40.9 1.9 1.5e-10 40.9 1.9 3.0 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain Usp PF00582.26 AIM20765.1 - 3.5e-05 24.4 0.5 0.0011 19.5 0.5 3.1 1 1 0 1 1 1 1 Universal stress protein family DUF2478 PF10649.9 AIM20765.1 - 0.019 14.6 0.2 1.7 8.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2478) HATPase_c_2 PF13581.6 AIM20765.1 - 0.036 14.0 0.0 0.091 12.7 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain DUF2975 PF11188.8 AIM20765.1 - 0.12 12.3 2.3 0.28 11.1 2.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) KdpC PF02669.15 AIM20766.1 - 1.9e-70 236.4 0.0 2.1e-70 236.3 0.0 1.0 1 0 0 1 1 1 1 K+-transporting ATPase, c chain LRV PF01816.17 AIM20766.1 - 0.031 14.7 2.0 0.062 13.7 0.2 2.5 2 0 0 2 2 2 0 Leucine rich repeat variant RNA_pol_Rpb6 PF01192.22 AIM20766.1 - 1.9 8.4 4.6 5.9 6.9 0.7 2.4 1 1 1 2 2 2 0 RNA polymerase Rpb6 Hydrolase PF00702.26 AIM20767.1 - 2.1e-35 122.9 3.4 3.4e-35 122.3 3.4 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 AIM20767.1 - 5.5e-34 117.3 1.8 5.5e-34 117.3 1.8 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 AIM20767.1 - 1.9e-05 24.5 0.6 0.00017 21.4 0.3 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PCB_OB PF17092.5 AIM20767.1 - 0.0066 17.2 0.0 0.02 15.7 0.0 1.8 1 0 0 1 1 1 1 Penicillin-binding protein OB-like domain HAD PF12710.7 AIM20767.1 - 0.0069 16.8 0.1 0.059 13.8 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Lectin_N PF03954.14 AIM20767.1 - 0.14 11.9 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain KdpA PF03814.15 AIM20768.1 - 1.2e-240 799.4 31.9 1.4e-240 799.2 31.9 1.0 1 0 0 1 1 1 1 Potassium-transporting ATPase A subunit DUF2517 PF10725.9 AIM20769.1 - 1.3e-35 121.0 1.0 1.4e-35 120.8 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2517) DUF1722 PF08349.11 AIM20770.1 - 1.9e-44 150.7 1.3 1.9e-43 147.5 1.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1722) DUF523 PF04463.12 AIM20770.1 - 3.5e-38 130.7 0.0 6.9e-38 129.8 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF523) FAD_binding_7 PF03441.14 AIM20771.1 - 6.4e-82 273.9 3.4 1e-81 273.3 3.4 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 AIM20771.1 - 6.3e-43 146.6 0.4 1.2e-42 145.7 0.4 1.5 1 0 0 1 1 1 1 DNA photolyase DPRP PF04244.13 AIM20771.1 - 0.045 13.6 0.1 0.076 12.9 0.1 1.3 1 0 0 1 1 1 0 Deoxyribodipyrimidine photo-lyase-related protein PDEase_II PF02112.15 AIM20772.1 - 1.5e-47 162.4 0.0 1.7e-46 158.9 0.0 1.9 1 1 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.7 AIM20772.1 - 1.4e-08 34.5 0.0 2.2e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 AIM20772.1 - 0.011 15.8 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily NIF3 PF01784.18 AIM20773.1 - 5.9e-57 193.1 0.0 7.1e-57 192.8 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Glyco_tran_10_N PF17039.5 AIM20773.1 - 0.22 12.0 0.0 0.34 11.4 0.0 1.2 1 0 0 1 1 1 0 Fucosyltransferase, N-terminal CT_C_D PF02682.16 AIM20774.1 - 1.1e-72 244.0 0.1 1.2e-72 243.9 0.1 1.0 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D Sigma70_r3 PF04539.16 AIM20774.1 - 0.015 15.4 0.0 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 Sigma-70 region 3 Pterin_4a PF01329.19 AIM20774.1 - 0.05 13.8 0.3 0.13 12.5 0.1 1.7 1 1 1 2 2 2 0 Pterin 4 alpha carbinolamine dehydratase CT_A_B PF02626.15 AIM20775.1 - 1.9e-98 329.3 0.0 2.1e-98 329.1 0.0 1.0 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B LamB_YcsF PF03746.16 AIM20776.1 - 5.2e-93 311.1 0.4 5.9e-93 310.9 0.4 1.0 1 0 0 1 1 1 1 LamB/YcsF family DUF969 PF06149.12 AIM20777.1 - 2.8e-90 301.5 3.6 3.2e-90 301.3 3.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF969) Na_H_antiport_2 PF13726.6 AIM20777.1 - 0.064 13.4 2.7 0.14 12.3 2.7 1.5 1 0 0 1 1 1 0 Na+-H+ antiporter family PrgI PF12666.7 AIM20777.1 - 0.55 11.0 7.6 2.9 8.7 2.0 2.9 2 1 0 2 2 2 0 PrgI family protein DUF979 PF06166.12 AIM20778.1 - 9e-129 429.1 21.7 1e-128 428.9 21.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF979) EBP PF05241.12 AIM20778.1 - 0.032 13.7 0.3 0.063 12.7 0.0 1.7 2 0 0 2 2 2 0 Emopamil binding protein Peptidase_C15 PF01470.17 AIM20779.1 - 1.5e-82 276.6 0.1 1.8e-82 276.4 0.1 1.0 1 0 0 1 1 1 1 Pyroglutamyl peptidase H2TH PF06831.14 AIM20780.1 - 4.7e-11 42.5 0.0 8.3e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Fapy_DNA_glyco PF01149.24 AIM20780.1 - 1.6e-09 38.4 0.0 2.5e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain zf-FPG_IleRS PF06827.14 AIM20780.1 - 4.1e-07 29.7 3.0 7.9e-07 28.8 3.0 1.5 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS zf-ACC PF17848.1 AIM20780.1 - 0.25 11.4 1.3 0.78 9.9 0.0 2.1 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain Citrate_synt PF00285.21 AIM20781.1 - 1.8e-132 441.8 0.0 2.1e-132 441.6 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Sdh_cyt PF01127.22 AIM20782.1 - 1.5e-30 105.7 5.8 1.7e-30 105.5 5.8 1.0 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Fumarate_red_D PF02313.17 AIM20782.1 - 0.0039 17.3 5.8 0.005 16.9 5.8 1.2 1 0 0 1 1 1 1 Fumarate reductase subunit D DUF3796 PF12676.7 AIM20782.1 - 0.041 14.3 1.4 0.088 13.2 0.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3796) Sdh_cyt PF01127.22 AIM20783.1 - 1.1e-05 25.4 10.1 1.5e-05 25.0 10.1 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit CybS PF05328.12 AIM20783.1 - 0.014 15.1 3.2 0.019 14.6 2.9 1.5 1 1 0 1 1 1 0 CybS, succinate dehydrogenase cytochrome B small subunit FAD_binding_2 PF00890.24 AIM20784.1 - 3.5e-118 395.3 5.9 4.3e-118 395.0 5.9 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 AIM20784.1 - 4.6e-35 120.4 0.1 7.5e-35 119.7 0.1 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 AIM20784.1 - 6.4e-05 22.3 1.8 0.0019 17.5 0.9 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AIM20784.1 - 0.00018 20.7 5.1 0.0026 16.9 1.9 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A HI0933_like PF03486.14 AIM20784.1 - 0.005 15.6 0.3 0.005 15.6 0.3 2.4 3 0 0 3 3 3 1 HI0933-like protein DAO PF01266.24 AIM20784.1 - 0.043 13.4 7.0 0.81 9.2 6.9 2.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 AIM20784.1 - 0.063 12.5 1.1 0.13 11.5 0.2 1.9 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 AIM20784.1 - 0.076 12.2 0.3 0.94 8.7 0.1 2.2 2 0 0 2 2 2 0 Thi4 family Fer2_3 PF13085.6 AIM20785.1 - 8.1e-32 109.5 0.0 1.2e-31 109.0 0.0 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 AIM20785.1 - 4.7e-10 39.9 1.5 8.3e-10 39.1 1.5 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 AIM20785.1 - 1.7e-08 34.8 4.3 1.5e-07 31.7 4.4 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 AIM20785.1 - 6.5e-08 32.6 1.3 1.2e-07 31.7 1.3 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AIM20785.1 - 0.00042 20.8 6.2 0.0029 18.2 6.8 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AIM20785.1 - 0.00074 19.6 4.3 0.0048 17.0 4.5 2.2 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_18 PF13746.6 AIM20785.1 - 0.0025 18.0 2.1 1.1 9.5 0.1 2.5 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AIM20785.1 - 0.0066 17.4 1.8 4.8 8.2 0.7 2.4 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_4 PF12800.7 AIM20785.1 - 0.43 11.2 9.3 7.9 7.3 0.4 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4 PF00037.27 AIM20785.1 - 0.45 10.4 13.7 0.54 10.2 0.5 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.7 AIM20785.1 - 4.1 7.7 11.3 0.59 10.3 0.5 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Transket_pyr PF02779.24 AIM20786.1 - 3.2e-67 225.7 0.0 5.8e-67 224.8 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 AIM20786.1 - 2.2e-54 183.3 0.0 5e-54 182.1 0.0 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 AIM20786.1 - 6.4e-50 169.8 0.0 1.3e-49 168.8 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component 2-oxogl_dehyd_N PF16078.5 AIM20786.1 - 3.9e-17 61.5 0.2 9.8e-16 57.1 0.1 2.5 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus PFOR_II PF17147.4 AIM20786.1 - 0.0073 16.6 0.0 0.021 15.1 0.0 1.7 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II 2-oxoacid_dh PF00198.23 AIM20787.1 - 3e-83 278.9 0.0 3.7e-83 278.5 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 AIM20787.1 - 3.5e-18 65.2 0.4 8e-18 64.1 0.3 1.7 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 AIM20787.1 - 6.7e-12 45.5 2.1 8.9e-12 45.1 0.7 2.0 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 AIM20787.1 - 0.1 12.4 0.0 0.3 10.9 0.0 1.8 1 0 0 1 1 1 0 Biotin-lipoyl like ATP-grasp_2 PF08442.10 AIM20788.1 - 1.6e-83 279.2 0.0 2.3e-83 278.7 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 AIM20788.1 - 2.4e-24 85.9 3.3 4e-24 85.2 3.3 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 AIM20788.1 - 1e-13 51.3 0.0 2.4e-13 50.1 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 AIM20788.1 - 0.0023 17.7 0.0 0.0042 16.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CoA_binding PF02629.19 AIM20789.1 - 1.7e-31 108.8 0.7 1.7e-31 108.8 0.7 2.1 3 1 0 3 3 3 1 CoA binding domain Ligase_CoA PF00549.19 AIM20789.1 - 4.5e-21 75.3 1.3 7.7e-21 74.5 1.3 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 AIM20789.1 - 3.8e-12 46.2 0.2 6.5e-12 45.4 0.2 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 AIM20789.1 - 0.00018 22.0 0.1 0.0011 19.4 0.0 2.3 3 0 0 3 3 3 1 CoA binding domain 5_nucleotid_C PF02872.18 AIM20790.1 - 3.1e-21 76.2 0.7 6.6e-21 75.2 0.1 1.8 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 AIM20790.1 - 6.1e-13 49.7 0.0 9.3e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PGA_cap PF09587.10 AIM20790.1 - 0.0051 16.3 0.0 0.0096 15.4 0.0 1.5 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap P53_C PF11619.8 AIM20790.1 - 0.049 13.7 0.0 2 8.5 0.0 2.4 2 0 0 2 2 2 0 Transcription factor P53 - C terminal domain Cyt_bd_oxida_I PF01654.17 AIM20791.1 - 6.6e-173 575.1 20.1 7.5e-173 574.9 20.1 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit I Cyt_bd_oxida_II PF02322.15 AIM20792.1 - 7.7e-109 363.7 36.7 9.1e-109 363.5 36.7 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit II YbgT_YccB PF08173.11 AIM20793.1 - 2.9e-15 56.1 4.8 3.1e-15 56.0 4.8 1.0 1 0 0 1 1 1 1 Membrane bound YbgT-like protein Cyd_oper_YbgE PF09600.10 AIM20794.1 - 3.1e-32 110.8 7.5 3.6e-32 110.6 7.5 1.1 1 0 0 1 1 1 1 Cyd operon protein YbgE (Cyd_oper_YbgE) DUF4229 PF14012.6 AIM20794.1 - 0.1 12.7 2.7 1.1 9.5 0.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4229) 4HBT PF03061.22 AIM20795.1 - 1.4e-20 73.4 0.1 2e-20 72.9 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 AIM20795.1 - 4e-13 49.9 0.1 4.6e-13 49.7 0.1 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Nuc_deoxyrib_tr PF05014.15 AIM20795.1 - 0.00025 21.0 0.1 0.00034 20.6 0.1 1.4 1 1 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase Acyl-ACP_TE PF01643.17 AIM20795.1 - 0.0071 15.7 0.0 0.008 15.5 0.0 1.1 1 0 0 1 1 1 1 Acyl-ACP thioesterase MotA_ExbB PF01618.16 AIM20796.1 - 1.7e-41 141.0 0.3 2.2e-41 140.6 0.3 1.2 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family Wzy_C_2 PF11846.8 AIM20796.1 - 0.11 12.3 1.1 1.2 9.1 0.2 2.1 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal ExbD PF02472.16 AIM20797.1 - 2.1e-24 86.1 0.1 2.4e-24 86.0 0.1 1.0 1 0 0 1 1 1 1 Biopolymer transport protein ExbD/TolR TolA PF06519.11 AIM20798.1 - 2.2e-35 120.8 0.0 2.2e-35 120.8 0.0 3.2 3 1 0 3 3 3 1 TolA C-terminal Hamartin PF04388.12 AIM20798.1 - 7.4 5.1 39.4 9.6 4.7 39.4 1.0 1 0 0 1 1 1 0 Hamartin protein PD40 PF07676.12 AIM20799.1 - 3.8e-40 135.0 4.3 1e-12 47.6 0.3 6.1 6 0 0 6 6 6 4 WD40-like Beta Propeller Repeat TolB_N PF04052.13 AIM20799.1 - 2.2e-32 111.4 0.0 5.1e-32 110.2 0.0 1.6 1 0 0 1 1 1 1 TolB amino-terminal domain DPPIV_N PF00930.21 AIM20799.1 - 5.8e-10 38.5 0.0 1.1e-05 24.3 0.0 3.3 1 1 2 3 3 3 3 Dipeptidyl peptidase IV (DPP IV) N-terminal region Pectate_lyase22 PF14583.6 AIM20799.1 - 1.5e-09 37.0 0.1 0.00015 20.6 0.1 4.2 3 1 2 5 5 5 3 Oligogalacturonate lyase Gmad1 PF10647.9 AIM20799.1 - 1.1e-07 31.9 2.8 0.016 15.0 0.0 4.2 2 1 2 4 4 4 3 Lipoprotein LpqB beta-propeller domain Peptidase_S9_N PF02897.15 AIM20799.1 - 0.0065 15.3 0.0 0.038 12.8 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Lactonase PF10282.9 AIM20799.1 - 0.053 12.8 0.1 3.1 7.0 0.0 2.3 1 1 1 2 2 2 0 Lactonase, 7-bladed beta-propeller OmpA PF00691.20 AIM20800.1 - 6.6e-22 77.7 0.3 2e-21 76.2 0.0 1.8 2 0 0 2 2 2 1 OmpA family Serglycin PF04360.12 AIM20800.1 - 0.026 14.4 0.4 0.039 13.9 0.4 1.3 1 0 0 1 1 1 0 Serglycin OMP_b-brl PF13505.6 AIM20800.1 - 0.048 13.8 0.4 0.058 13.5 0.4 1.2 1 0 0 1 1 1 0 Outer membrane protein beta-barrel domain Glyco_transf_20 PF00982.21 AIM20800.1 - 0.071 11.8 0.0 0.096 11.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 20 TolA_bind_tri PF16331.5 AIM20801.1 - 6.5e-24 83.8 15.8 1.1e-23 83.1 15.8 1.3 1 0 0 1 1 1 1 TolA binding protein trimerisation TPR_6 PF13174.6 AIM20801.1 - 1.7e-20 72.2 10.9 3.9e-08 33.4 0.0 4.1 4 1 0 4 4 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 AIM20801.1 - 9.6e-12 44.1 0.8 0.0035 17.3 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 AIM20801.1 - 2.4e-10 40.9 1.6 8e-09 36.0 0.2 3.5 2 1 2 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 AIM20801.1 - 1e-08 35.6 7.9 0.00097 19.6 0.2 3.3 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 AIM20801.1 - 9.8e-08 32.2 0.0 0.0041 17.8 0.0 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat YfiO PF13525.6 AIM20801.1 - 1.4e-07 31.5 10.3 8e-07 29.0 10.3 2.0 1 1 0 1 1 1 1 Outer membrane lipoprotein TPR_8 PF13181.6 AIM20801.1 - 9.1e-07 28.6 3.8 0.2 11.9 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 AIM20801.1 - 0.00014 22.0 3.0 0.73 10.3 0.3 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 AIM20801.1 - 0.00022 20.9 5.5 3 7.8 1.5 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_18 PF13512.6 AIM20801.1 - 0.00028 21.0 7.7 0.15 12.2 1.3 2.8 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 AIM20801.1 - 0.00046 20.4 0.3 3.7 7.9 0.1 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 AIM20801.1 - 0.00063 19.9 6.0 0.0012 19.1 1.0 3.2 2 1 2 4 4 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 AIM20801.1 - 0.0011 18.9 9.4 1.5 8.9 0.3 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Spc7 PF08317.11 AIM20801.1 - 0.0019 17.1 2.1 0.0029 16.5 2.1 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein TPR_21 PF09976.9 AIM20801.1 - 0.0025 17.6 3.8 0.0025 17.6 3.8 2.7 1 1 0 2 2 2 1 Tetratricopeptide repeat-like domain TPR_9 PF13371.6 AIM20801.1 - 0.0034 17.5 0.0 0.18 11.9 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat HrpB7 PF09486.10 AIM20801.1 - 0.0053 17.2 4.3 0.009 16.4 4.3 1.4 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) DUF4810 PF16068.5 AIM20801.1 - 0.0093 16.5 9.6 0.098 13.2 0.1 4.0 2 2 1 3 3 3 1 Domain of unknown function (DUF4810) COG2 PF06148.11 AIM20801.1 - 0.011 15.8 1.1 0.021 14.9 0.6 1.6 2 0 0 2 2 1 0 COG (conserved oligomeric Golgi) complex component, COG2 CASP_C PF08172.12 AIM20801.1 - 0.012 14.9 0.8 0.021 14.2 0.8 1.3 1 0 0 1 1 1 0 CASP C terminal IFT57 PF10498.9 AIM20801.1 - 0.015 14.3 3.4 0.023 13.7 3.4 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 GLE1 PF07817.13 AIM20801.1 - 0.019 14.2 0.3 0.043 13.0 0.3 1.6 1 0 0 1 1 1 0 GLE1-like protein Exonuc_VII_L PF02601.15 AIM20801.1 - 0.024 14.2 2.2 0.018 14.6 0.9 1.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 AIM20801.1 - 0.027 12.4 0.0 0.036 12.0 0.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Staphopain_pro PF14731.6 AIM20801.1 - 0.053 13.5 2.6 0.064 13.2 1.7 1.7 2 0 0 2 2 1 0 Staphopain proregion COG5 PF10392.9 AIM20801.1 - 0.069 13.3 1.6 0.15 12.2 1.6 1.5 1 0 0 1 1 1 0 Golgi transport complex subunit 5 TPR_11 PF13414.6 AIM20801.1 - 0.075 12.7 11.5 1.4 8.6 3.4 4.3 3 2 1 4 4 3 0 TPR repeat Prominin PF05478.11 AIM20801.1 - 0.12 10.3 3.0 0.17 9.8 3.0 1.1 1 0 0 1 1 1 0 Prominin Syntaxin_2 PF14523.6 AIM20801.1 - 0.13 12.6 16.4 1.2 9.5 12.6 2.9 2 1 0 2 2 2 0 Syntaxin-like protein FliD_C PF07195.12 AIM20801.1 - 0.14 11.6 5.3 0.27 10.6 1.8 2.3 3 0 0 3 3 2 0 Flagellar hook-associated protein 2 C-terminus Utp13 PF08625.11 AIM20801.1 - 0.28 11.1 2.8 0.2 11.6 0.2 2.1 2 1 0 2 2 2 0 Utp13 specific WD40 associated domain SlyX PF04102.12 AIM20801.1 - 0.3 11.7 15.0 0.13 12.9 11.1 2.3 2 1 0 2 2 1 0 SlyX Wzy_C_2 PF11846.8 AIM20801.1 - 0.51 10.2 7.0 0.14 12.1 3.2 2.0 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal MscS_porin PF12795.7 AIM20801.1 - 0.54 9.8 25.3 0.29 10.6 12.5 2.7 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain DUF4404 PF14357.6 AIM20801.1 - 0.55 10.9 3.8 1.3 9.7 3.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) SHE3 PF17078.5 AIM20801.1 - 0.55 9.9 6.1 0.094 12.4 1.4 1.8 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 Herpes_capsid PF06112.11 AIM20801.1 - 0.73 9.9 11.0 1.5 8.8 11.0 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF16 PF01519.16 AIM20801.1 - 1.1 9.8 6.1 2.4 8.7 6.1 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 Fib_alpha PF08702.10 AIM20801.1 - 1.7 8.8 6.5 0.24 11.6 2.0 2.0 3 0 0 3 3 1 0 Fibrinogen alpha/beta chain family PilO PF04350.13 AIM20801.1 - 2.2 8.4 8.8 5.8 7.1 0.1 3.2 3 0 0 3 3 3 0 Pilus assembly protein, PilO DUF3552 PF12072.8 AIM20801.1 - 6.8 6.1 10.2 0.28 10.6 4.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) RPN6_N PF18055.1 AIM20801.1 - 7.3 7.0 8.0 24 5.3 0.6 3.0 2 1 1 3 3 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain DASH_Spc34 PF08657.10 AIM20801.1 - 7.5 6.3 8.5 8.9 6.0 4.0 2.6 2 1 1 3 3 3 0 DASH complex subunit Spc34 NadA PF02445.16 AIM20802.1 - 6.3e-104 347.3 0.1 7.2e-104 347.1 0.1 1.0 1 0 0 1 1 1 1 Quinolinate synthetase A protein NMN_transporter PF04973.12 AIM20803.1 - 9.4e-53 178.8 29.9 1.2e-52 178.4 29.9 1.1 1 0 0 1 1 1 1 Nicotinamide mononucleotide transporter Cation_efflux PF01545.21 AIM20804.1 - 7.5e-53 179.2 15.6 8.9e-53 179.0 15.6 1.1 1 0 0 1 1 1 1 Cation efflux family OPT PF03169.15 AIM20804.1 - 0.00044 19.0 0.0 0.00044 19.0 0.0 2.2 2 1 0 2 2 2 1 OPT oligopeptide transporter protein ZT_dimer PF16916.5 AIM20804.1 - 0.014 15.5 0.9 0.03 14.4 0.9 1.5 1 0 0 1 1 1 0 Dimerisation domain of Zinc Transporter TM_helix PF05552.12 AIM20804.1 - 0.048 13.6 2.2 0.048 13.6 2.2 2.8 3 0 0 3 3 3 0 Conserved TM helix NADH-u_ox-rdase PF10785.9 AIM20804.1 - 0.2 12.4 0.3 0.54 11.0 0.0 1.8 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Vut_1 PF02592.15 AIM20804.1 - 0.55 10.5 8.2 0.064 13.6 3.9 1.6 2 0 0 2 2 2 0 Putative vitamin uptake transporter DUF1129 PF06570.11 AIM20804.1 - 2.8 7.4 6.6 0.66 9.4 2.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) SBP_bac_3 PF00497.20 AIM20805.1 - 1.4e-39 135.9 1.7 3.6e-23 82.2 0.0 3.3 3 0 0 3 3 3 2 Bacterial extracellular solute-binding proteins, family 3 HATPase_c PF02518.26 AIM20805.1 - 9.8e-28 96.9 0.1 1.7e-27 96.1 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AIM20805.1 - 8.7e-15 54.9 0.0 3e-14 53.1 0.0 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 AIM20805.1 - 4.9e-13 48.9 0.2 4.9e-13 48.9 0.2 3.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Hpt PF01627.23 AIM20805.1 - 1.6e-09 37.9 6.4 1.6e-09 37.9 6.4 2.9 2 0 0 2 2 2 1 Hpt domain Phosphonate-bd PF12974.7 AIM20805.1 - 0.084 12.4 0.7 2.7 7.5 0.0 2.9 2 1 0 2 2 2 0 ABC transporter, phosphonate, periplasmic substrate-binding protein PI-PLC-C1 PF16670.5 AIM20805.1 - 0.095 11.8 0.1 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 Phosphoinositide phospholipase C, Ca2+-dependent Response_reg PF00072.24 AIM20806.1 - 8.6e-20 71.0 0.0 1.2e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AIM20806.1 - 1.7e-19 69.1 0.1 2.8e-19 68.4 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_23 PF13384.6 AIM20806.1 - 0.00087 19.0 0.2 0.0025 17.6 0.0 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_24 PF13412.6 AIM20806.1 - 0.0016 17.9 0.1 0.0034 16.9 0.1 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Sigma70_r4_2 PF08281.12 AIM20806.1 - 0.009 15.7 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_20 PF12840.7 AIM20806.1 - 0.032 14.3 0.1 0.13 12.3 0.1 1.9 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_38 PF13936.6 AIM20806.1 - 0.058 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 AIM20806.1 - 0.061 12.9 0.0 0.15 11.6 0.0 1.7 1 1 0 1 1 1 0 Sigma-70, region 4 HTH_10 PF04967.12 AIM20806.1 - 0.13 12.1 0.2 1.1 9.1 0.1 2.4 2 0 0 2 2 2 0 HTH DNA binding domain DAHP_synth_1 PF00793.20 AIM20807.1 - 6.9e-107 356.4 0.0 8e-107 356.2 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DUF898 PF05987.13 AIM20808.1 - 8.9e-96 320.9 26.8 1.2e-95 320.5 26.8 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF898) DUF1375 PF07119.12 AIM20808.1 - 0.029 14.7 0.2 0.13 12.7 0.2 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1375) Lambda_Bor PF06291.11 AIM20808.1 - 0.09 12.8 0.2 0.23 11.5 0.2 1.7 1 0 0 1 1 1 0 Bor protein Peptidase_M48 PF01435.18 AIM20809.1 - 4.9e-25 88.5 0.5 1.2e-24 87.2 0.5 1.6 1 1 0 1 1 1 1 Peptidase family M48 His_Phos_1 PF00300.22 AIM20810.1 - 4.9e-37 127.5 0.2 1.7e-30 106.2 0.5 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) PsiF_repeat PF07769.14 AIM20811.1 - 1.4e-33 114.5 23.7 6.7e-19 67.5 7.3 2.4 2 1 0 2 2 2 2 psiF repeat Aldose_epim PF01263.20 AIM20812.1 - 2e-80 270.3 0.0 2.3e-80 270.2 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase GalKase_gal_bdg PF10509.9 AIM20813.1 - 3.4e-23 81.0 0.1 5.8e-23 80.2 0.1 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 AIM20813.1 - 3.7e-15 55.9 1.0 9.1e-15 54.6 1.0 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 AIM20813.1 - 1.9e-12 47.3 0.1 6.4e-12 45.7 0.0 1.9 2 0 0 2 2 2 1 GHMP kinases C terminal GalP_UDP_tr_C PF02744.17 AIM20814.1 - 4e-70 234.9 0.1 9.1e-70 233.7 0.1 1.5 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain GalP_UDP_transf PF01087.22 AIM20814.1 - 5.1e-69 232.4 0.0 7.4e-69 231.9 0.0 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain HIT PF01230.23 AIM20814.1 - 0.0043 17.7 0.0 0.026 15.2 0.0 2.1 2 0 0 2 2 2 1 HIT domain DUF4921 PF16268.5 AIM20814.1 - 0.14 10.9 0.7 0.33 9.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4921) CPBP PF02517.16 AIM20815.1 - 2.1e-19 69.7 11.3 2.1e-19 69.7 11.3 2.8 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease Isochorismatase PF00857.20 AIM20816.1 - 4.5e-35 121.4 0.0 5.1e-35 121.2 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family CoA_binding_3 PF13727.6 AIM20816.1 - 0.046 13.7 0.1 6.5 6.7 0.0 2.1 2 0 0 2 2 2 0 CoA-binding domain Acyl_transf_1 PF00698.21 AIM20816.1 - 0.098 12.1 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Acyl transferase domain ABC_tran PF00005.27 AIM20817.1 - 1.8e-45 154.8 0.0 8.9e-25 87.8 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 AIM20817.1 - 5.4e-21 75.7 4.6 4e-08 33.4 0.2 4.1 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIM20817.1 - 9.6e-12 44.8 0.1 0.00016 21.2 0.1 3.6 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AIM20817.1 - 2.2e-08 34.7 8.6 1.2e-05 25.7 1.9 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 AIM20817.1 - 5.7e-08 32.4 0.0 0.0046 16.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 AIM20817.1 - 1.6e-07 32.1 0.1 0.011 16.3 0.0 2.4 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.6 AIM20817.1 - 2.8e-06 27.6 1.0 0.19 12.0 0.1 3.6 2 2 0 2 2 2 2 AAA domain AAA_33 PF13671.6 AIM20817.1 - 6.3e-06 26.4 0.1 0.019 15.1 0.0 3.2 3 1 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 AIM20817.1 - 1.4e-05 25.0 0.1 0.25 11.2 0.0 3.1 3 0 0 3 3 3 2 RsgA GTPase AAA_28 PF13521.6 AIM20817.1 - 2.1e-05 24.8 0.1 0.0077 16.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 AIM20817.1 - 3e-05 23.9 0.0 0.2 11.4 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain SbcCD_C PF13558.6 AIM20817.1 - 3.3e-05 24.0 0.1 0.033 14.4 0.1 3.4 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit IstB_IS21 PF01695.17 AIM20817.1 - 5.6e-05 23.0 2.0 0.12 12.1 0.1 4.2 3 1 1 4 4 4 1 IstB-like ATP binding protein AAA PF00004.29 AIM20817.1 - 0.00015 22.2 0.0 0.046 14.1 0.0 3.3 2 1 1 3 3 3 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 AIM20817.1 - 0.00018 21.5 4.5 0.043 13.7 0.3 3.6 3 1 1 4 4 4 1 NACHT domain MMR_HSR1 PF01926.23 AIM20817.1 - 0.00023 21.2 0.0 0.41 10.7 0.1 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 AIM20817.1 - 0.00031 21.3 0.0 0.11 13.0 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_27 PF13514.6 AIM20817.1 - 0.00051 19.7 0.0 0.87 9.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.22 AIM20817.1 - 0.0011 18.2 0.0 1.8 7.7 0.0 2.8 2 1 0 2 2 2 2 NB-ARC domain Zeta_toxin PF06414.12 AIM20817.1 - 0.0015 17.9 0.0 0.84 8.9 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_25 PF13481.6 AIM20817.1 - 0.0016 18.0 0.2 0.43 10.1 0.2 3.3 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 AIM20817.1 - 0.0021 18.4 0.0 0.92 9.9 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_7 PF12775.7 AIM20817.1 - 0.0023 17.5 0.0 0.37 10.3 0.0 2.5 3 0 0 3 3 2 1 P-loop containing dynein motor region HopA1 PF17914.1 AIM20817.1 - 0.0023 17.7 0.1 0.14 11.9 0.0 3.0 3 0 0 3 3 3 1 HopA1 effector protein family AAA_30 PF13604.6 AIM20817.1 - 0.0024 17.6 0.1 7.1 6.3 0.0 3.3 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 AIM20817.1 - 0.0065 16.6 0.0 1.2 9.2 0.0 2.4 2 0 0 2 2 2 1 Dynamin family AAA_14 PF13173.6 AIM20817.1 - 0.011 15.8 0.0 1.5 8.9 0.0 2.7 2 1 0 2 2 2 0 AAA domain DUF3584 PF12128.8 AIM20817.1 - 0.021 12.4 0.0 0.063 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) AAA_24 PF13479.6 AIM20817.1 - 0.028 14.1 0.0 8.2 6.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Ploopntkinase1 PF18748.1 AIM20817.1 - 0.03 13.9 0.0 0.72 9.3 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 Mg_chelatase PF01078.21 AIM20817.1 - 0.04 13.3 0.0 1.3 8.4 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_13 PF13166.6 AIM20817.1 - 0.058 12.0 0.0 4.2 5.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 AIM20817.1 - 0.064 13.3 0.0 5.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_10 PF12846.7 AIM20817.1 - 0.064 12.2 0.0 5 5.9 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain FtsK_SpoIIIE PF01580.18 AIM20817.1 - 0.46 9.8 3.0 11 5.3 0.0 3.0 3 1 1 4 4 4 0 FtsK/SpoIIIE family TOBE PF03459.17 AIM20818.1 - 1.1e-32 112.1 4.7 1.5e-16 60.5 0.1 2.4 2 0 0 2 2 2 2 TOBE domain HTH_1 PF00126.27 AIM20818.1 - 4.4e-13 49.0 0.2 1.3e-12 47.4 0.0 2.0 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family TOBE_2 PF08402.10 AIM20818.1 - 0.00017 21.7 2.8 0.0009 19.4 0.7 2.3 1 1 1 2 2 2 1 TOBE domain TOBE_3 PF12857.7 AIM20818.1 - 0.021 14.7 0.4 5.8 6.9 0.1 2.8 2 1 0 2 2 2 0 TOBE-like domain DHBP_synthase PF00926.19 AIM20818.1 - 0.1 12.1 0.1 1.6 8.2 0.0 2.2 1 1 1 2 2 2 0 3,4-dihydroxy-2-butanone 4-phosphate synthase AcrZ PF10766.9 AIM20819.1 - 2.2e-28 97.6 1.3 2.4e-28 97.4 1.3 1.0 1 0 0 1 1 1 1 Multidrug efflux pump-associated protein AcrZ TadE PF07811.12 AIM20819.1 - 0.03 14.6 1.7 0.032 14.5 1.7 1.1 1 0 0 1 1 1 0 TadE-like protein Insulin_TMD PF17870.1 AIM20819.1 - 0.1 12.6 2.3 0.13 12.4 2.3 1.1 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Tad PF13400.6 AIM20819.1 - 0.13 12.6 1.6 0.15 12.4 1.6 1.1 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like SBP_bac_11 PF13531.6 AIM20820.1 - 1.9e-51 175.0 3.8 2.2e-51 174.8 3.8 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AIM20820.1 - 3.6e-16 60.0 4.0 7.8e-16 58.9 4.0 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AIM20820.1 - 0.00011 21.8 0.6 0.00044 19.7 0.6 2.0 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein BPD_transp_1 PF00528.22 AIM20821.1 - 2.2e-24 86.2 13.8 2.5e-24 86.0 13.8 1.1 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 AIM20822.1 - 2.7e-28 99.2 0.0 4.5e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter TOBE PF03459.17 AIM20822.1 - 1.3e-20 73.4 0.2 9.1e-17 61.1 0.0 2.8 2 1 0 2 2 2 2 TOBE domain AAA_23 PF13476.6 AIM20822.1 - 0.00017 22.2 0.1 0.00025 21.6 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 AIM20822.1 - 0.00083 19.3 6.2 0.13 12.1 1.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 AIM20822.1 - 0.0014 18.6 0.1 0.0028 17.6 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 AIM20822.1 - 0.0021 17.6 0.0 0.21 11.0 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AIM20822.1 - 0.0048 16.6 0.1 0.016 15.0 0.1 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 AIM20822.1 - 0.026 14.6 0.0 0.052 13.6 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 AIM20822.1 - 0.056 13.7 1.0 0.18 12.0 0.1 2.1 2 0 0 2 2 2 0 AAA domain Hydrolase_3 PF08282.12 AIM20823.1 - 7e-63 212.7 0.0 8e-63 212.6 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 AIM20823.1 - 1.3e-15 57.7 0.2 2.5e-07 30.5 0.1 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 AIM20823.1 - 8.3e-11 42.6 1.7 0.00043 20.6 0.0 3.6 3 1 1 4 4 4 3 haloacid dehalogenase-like hydrolase HAD PF12710.7 AIM20823.1 - 6.2e-10 39.8 6.0 0.00011 22.6 0.1 3.9 1 1 3 4 4 4 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AIM20823.1 - 2.1e-05 24.6 0.1 7.4e-05 22.8 0.1 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 AIM20823.1 - 0.00041 20.5 0.3 1.4 9.0 0.0 3.2 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 AIM20823.1 - 0.00045 19.9 0.6 3.5 7.2 0.0 3.1 2 1 1 3 3 3 2 HAD superfamily, subfamily IIIB (Acid phosphatase) Lactonase PF10282.9 AIM20824.1 - 5e-91 305.5 0.0 6e-91 305.3 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SGL PF08450.12 AIM20824.1 - 0.0068 16.0 0.0 0.53 9.8 0.0 2.7 2 1 1 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region DUF1513 PF07433.11 AIM20824.1 - 0.1 11.7 0.1 11 5.0 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1513) MMS1_N PF10433.9 AIM20824.1 - 0.1 11.2 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Arylesterase PF01731.20 AIM20824.1 - 0.16 12.2 0.0 1.4e+02 2.8 0.0 4.0 4 0 0 4 4 4 0 Arylesterase PBP PF01161.20 AIM20825.1 - 2.7e-38 131.3 0.0 3.1e-38 131.1 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Cation_efflux PF01545.21 AIM20826.1 - 3.3e-40 138.0 10.0 4e-40 137.7 10.0 1.1 1 0 0 1 1 1 1 Cation efflux family UbiA PF01040.18 AIM20826.1 - 0.94 8.7 15.0 1.8 7.8 1.4 2.2 2 0 0 2 2 2 0 UbiA prenyltransferase family Trns_repr_metal PF02583.17 AIM20827.1 - 1.5e-23 82.9 3.4 1.7e-23 82.8 3.4 1.0 1 0 0 1 1 1 1 Metal-sensitive transcriptional repressor DUF4349 PF14257.6 AIM20827.1 - 0.039 13.4 0.9 0.045 13.2 0.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF1232 PF06803.12 AIM20828.1 - 2.5e-14 52.8 11.9 6e-14 51.5 11.9 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1232) Aminotran_3 PF00202.21 AIM20829.1 - 1.4e-128 429.1 0.0 1.7e-128 428.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 AIM20829.1 - 0.11 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase BATS PF06968.13 AIM20830.1 - 8.7e-21 73.9 0.0 1.9e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 AIM20830.1 - 1.2e-18 68.1 0.0 2.8e-18 66.9 0.0 1.6 2 0 0 2 2 2 1 Radical SAM superfamily Aminotran_1_2 PF00155.21 AIM20831.1 - 3.4e-58 197.6 0.0 4.2e-58 197.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 AIM20831.1 - 2.3e-07 30.1 0.0 3.5e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 AIM20831.1 - 7.7e-06 25.4 0.0 1.4e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 AIM20831.1 - 0.00048 18.8 0.0 0.00067 18.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 AIM20831.1 - 0.0021 17.4 0.2 0.0099 15.2 0.2 2.0 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family SHMT PF00464.19 AIM20831.1 - 0.02 13.5 0.1 0.066 11.8 0.0 1.7 2 0 0 2 2 2 0 Serine hydroxymethyltransferase OKR_DC_1 PF01276.20 AIM20831.1 - 0.034 12.9 0.0 0.054 12.2 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Methyltransf_11 PF08241.12 AIM20832.1 - 4.9e-25 88.0 0.0 8.2e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AIM20832.1 - 3.2e-19 69.4 0.0 5.6e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AIM20832.1 - 1.7e-14 53.9 0.0 2.1e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AIM20832.1 - 1.1e-13 51.3 0.0 1.5e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIM20832.1 - 5.4e-12 46.3 0.0 9e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AIM20832.1 - 4.4e-10 39.3 0.0 7.7e-10 38.5 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 AIM20832.1 - 0.00082 19.3 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase NodS PF05401.11 AIM20832.1 - 0.002 17.8 0.0 0.0025 17.5 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_29 PF03141.16 AIM20832.1 - 0.0021 16.7 0.0 0.0025 16.4 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_32 PF13679.6 AIM20832.1 - 0.0071 16.3 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 AIM20832.1 - 0.028 13.3 0.0 0.059 12.3 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) CMAS PF02353.20 AIM20832.1 - 0.039 13.2 0.0 0.09 12.1 0.0 1.5 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase MTS PF05175.14 AIM20832.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.19 AIM20832.1 - 0.17 12.0 0.0 0.34 11.0 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase AAA_26 PF13500.6 AIM20833.1 - 3.2e-40 138.1 0.0 3.8e-40 137.8 0.0 1.0 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 AIM20833.1 - 2e-13 50.5 0.0 2.5e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF1611 PF07755.11 AIM20833.1 - 1.3e-05 24.6 0.0 0.0009 18.6 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF1611_C) P-loop domain ABC_tran PF00005.27 AIM20834.1 - 7.4e-09 36.2 0.0 9.7e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter UvrB_inter PF17757.1 AIM20835.1 - 1.1e-30 105.7 0.1 2.9e-30 104.3 0.1 1.8 1 0 0 1 1 1 1 UvrB interaction domain UvrB PF12344.8 AIM20835.1 - 6.3e-21 74.0 0.1 1.9e-20 72.4 0.1 1.9 1 0 0 1 1 1 1 Ultra-violet resistance protein B Helicase_C PF00271.31 AIM20835.1 - 3.4e-18 66.0 0.1 1.3e-17 64.1 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 AIM20835.1 - 1.1e-10 41.8 0.0 2.5e-09 37.4 0.0 2.9 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit UVR PF02151.19 AIM20835.1 - 5.7e-09 35.4 3.7 2e-08 33.7 3.7 2.0 1 0 0 1 1 1 1 UvrB/uvrC motif AAA_30 PF13604.6 AIM20835.1 - 0.00056 19.7 0.0 0.02 14.6 0.0 2.7 3 0 0 3 3 3 1 AAA domain DEAD PF00270.29 AIM20835.1 - 0.00064 19.5 0.2 0.011 15.5 0.0 3.0 4 1 0 4 4 4 1 DEAD/DEAH box helicase AAA_19 PF13245.6 AIM20835.1 - 0.0033 17.8 0.0 3.1 8.1 0.0 2.8 2 1 0 2 2 2 2 AAA domain UvrD-helicase PF00580.21 AIM20835.1 - 0.036 13.6 2.1 6.5 6.2 0.3 2.6 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain zf-C4H2 PF10146.9 AIM20835.1 - 0.17 12.2 0.3 0.48 10.7 0.3 1.8 1 0 0 1 1 1 0 Zinc finger-containing protein VF530 PF09905.9 AIM20836.1 - 8.8e-35 118.7 0.0 1.1e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 DNA-binding protein VF530 UPF0052 PF01933.18 AIM20837.1 - 1.3e-74 251.1 0.1 1.6e-74 250.8 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 Mob_synth_C PF06463.13 AIM20838.1 - 8.4e-38 129.2 0.0 1.4e-37 128.5 0.0 1.4 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 AIM20838.1 - 3.6e-29 102.3 0.0 4.7e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 AIM20838.1 - 3.5e-07 30.6 0.0 6.3e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AIM20838.1 - 0.0017 18.4 0.0 0.0033 17.5 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain DUF1272 PF06906.11 AIM20838.1 - 0.016 15.3 0.6 8 6.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) AhpC-TSA PF00578.21 AIM20838.1 - 0.021 14.8 0.0 2.1 8.2 0.0 2.3 2 0 0 2 2 2 0 AhpC/TSA family MoCF_biosynth PF00994.24 AIM20839.1 - 1.1e-36 125.6 0.1 1.4e-36 125.4 0.1 1.0 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoaC PF01967.21 AIM20840.1 - 4.9e-57 191.8 2.6 5.6e-57 191.6 2.6 1.0 1 0 0 1 1 1 1 MoaC family ThiS PF02597.20 AIM20841.1 - 1.3e-15 57.8 0.0 1.7e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 ThiS family TGS PF02824.21 AIM20841.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 TGS domain MoaE PF02391.17 AIM20842.1 - 5.1e-36 123.4 0.0 6.2e-36 123.1 0.0 1.1 1 0 0 1 1 1 1 MoaE protein Bax1-I PF01027.20 AIM20843.1 - 1.2e-60 204.8 35.9 1.4e-60 204.7 35.9 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.7 AIM20843.1 - 0.0025 17.4 30.2 0.0064 16.1 30.2 1.7 1 1 0 1 1 1 1 Bax inhibitor 1 like NDUF_B4 PF07225.12 AIM20843.1 - 0.15 12.0 0.2 0.32 10.9 0.2 1.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) UCR_6-4kD PF08997.10 AIM20843.1 - 0.59 10.1 0.1 0.59 10.1 0.1 3.2 3 0 0 3 3 3 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein ABC2_membrane_3 PF12698.7 AIM20844.1 - 1.5e-48 165.7 16.7 1.8e-48 165.4 16.7 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 AIM20844.1 - 1.7e-33 115.8 11.1 1.7e-33 115.8 11.1 2.1 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_2 PF12679.7 AIM20844.1 - 1.4e-26 93.4 12.2 1.7e-26 93.2 12.2 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 AIM20844.1 - 3e-05 24.1 12.0 3e-05 24.1 12.0 2.2 2 1 0 2 2 2 1 ABC-2 family transporter protein 12TM_1 PF09847.9 AIM20844.1 - 0.0044 16.2 12.1 0.095 11.8 0.1 2.2 2 0 0 2 2 2 2 Membrane protein of 12 TMs DUF373 PF04123.13 AIM20844.1 - 5.7 6.3 12.3 4.8 6.5 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF373) ABC2_membrane_3 PF12698.7 AIM20845.1 - 8.8e-43 146.7 16.2 1.1e-42 146.4 16.2 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 AIM20845.1 - 3.3e-37 128.3 10.3 4.2e-37 128.0 10.3 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 AIM20845.1 - 6.8e-26 91.0 28.0 8.7e-23 80.8 21.0 2.5 2 1 0 2 2 2 2 ABC-2 type transporter ABC2_membrane_4 PF12730.7 AIM20845.1 - 6.4e-06 26.2 12.8 6.4e-06 26.2 12.8 2.7 3 1 1 4 4 4 1 ABC-2 family transporter protein ABC_tran PF00005.27 AIM20846.1 - 1.7e-55 187.3 0.0 2.8e-26 92.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 AIM20846.1 - 3.2e-17 63.3 1.7 0.00013 21.9 0.0 4.2 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AIM20846.1 - 8.4e-07 29.7 1.1 0.0032 18.0 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 AIM20846.1 - 1.1e-06 28.2 2.2 0.0067 16.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 AIM20846.1 - 2.6e-05 24.0 1.0 0.011 15.4 0.2 2.9 3 1 0 3 3 2 1 AAA domain MeaB PF03308.16 AIM20846.1 - 8.1e-05 21.7 0.5 0.17 10.9 0.0 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 AIM20846.1 - 0.0001 22.8 2.0 0.11 12.8 0.1 3.4 2 1 1 3 3 3 1 AAA ATPase domain SRP54 PF00448.22 AIM20846.1 - 0.00011 21.9 1.2 0.093 12.3 0.1 2.3 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 AIM20846.1 - 0.00024 21.1 0.3 0.067 13.1 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_27 PF13514.6 AIM20846.1 - 0.00027 20.6 0.1 0.012 15.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 AIM20846.1 - 0.00033 20.9 1.0 0.069 13.4 0.1 3.1 2 1 0 2 2 2 1 AAA domain Rad17 PF03215.15 AIM20846.1 - 0.00055 19.9 0.2 0.27 11.1 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain AAA PF00004.29 AIM20846.1 - 0.001 19.5 2.7 0.36 11.3 0.0 3.7 3 2 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 AIM20846.1 - 0.0014 18.4 1.6 0.81 9.4 0.1 2.4 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 AIM20846.1 - 0.0015 18.6 0.3 1.1 9.4 0.0 3.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase CLP1_P PF16575.5 AIM20846.1 - 0.0033 17.3 0.1 1.2 8.9 0.0 2.2 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop TsaE PF02367.17 AIM20846.1 - 0.0047 16.9 1.0 0.21 11.6 0.2 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cdc6_C PF09079.11 AIM20846.1 - 0.0052 16.7 0.0 5.2 7.1 0.0 2.6 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain CbiA PF01656.23 AIM20846.1 - 0.0074 16.4 0.0 0.49 10.5 0.0 2.3 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_5 PF07728.14 AIM20846.1 - 0.014 15.4 2.2 2 8.4 0.3 3.2 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 AIM20846.1 - 0.014 14.7 5.0 1.2 8.4 0.3 3.7 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 AIM20846.1 - 0.014 15.7 0.6 12 6.4 0.0 3.3 3 0 0 3 3 3 0 RNA helicase AAA_33 PF13671.6 AIM20846.1 - 0.018 15.2 2.2 0.65 10.1 0.2 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 AIM20846.1 - 0.021 15.2 0.2 6.9 7.0 0.0 2.9 3 0 0 3 3 2 0 AAA domain NTPase_1 PF03266.15 AIM20846.1 - 0.024 14.5 0.7 2 8.3 0.1 2.7 3 0 0 3 3 2 0 NTPase MukB PF04310.12 AIM20846.1 - 0.034 14.0 0.4 1.6 8.5 0.0 2.3 2 0 0 2 2 2 0 MukB N-terminal SMC_N PF02463.19 AIM20846.1 - 0.037 13.5 0.0 7 6.0 0.0 2.9 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain Thymidylate_kin PF02223.17 AIM20846.1 - 0.047 13.4 0.4 0.82 9.3 0.0 2.5 2 0 0 2 2 2 0 Thymidylate kinase ATP_bind_1 PF03029.17 AIM20846.1 - 0.055 13.2 0.5 1.9 8.2 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.6 AIM20846.1 - 0.068 12.7 1.7 1.1 8.8 0.2 3.1 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 AIM20846.1 - 0.069 13.2 0.1 11 6.1 0.0 3.4 3 1 1 4 4 3 0 AAA domain SbcCD_C PF13558.6 AIM20846.1 - 0.07 13.4 0.0 26 5.1 0.0 3.5 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 AIM20846.1 - 0.074 13.6 2.6 0.45 11.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain Fer4_NifH PF00142.18 AIM20846.1 - 0.082 12.3 2.7 1.3 8.4 0.4 2.5 2 1 1 3 3 3 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_15 PF13175.6 AIM20846.1 - 0.094 12.4 0.0 4.6 6.8 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain IstB_IS21 PF01695.17 AIM20846.1 - 0.11 12.3 0.1 56 3.4 0.0 3.7 4 0 0 4 4 4 0 IstB-like ATP binding protein KAP_NTPase PF07693.14 AIM20846.1 - 0.14 11.4 0.0 0.27 10.5 0.0 1.4 2 0 0 2 2 1 0 KAP family P-loop domain AAA_7 PF12775.7 AIM20846.1 - 0.15 11.6 0.4 14 5.1 0.1 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_28 PF13521.6 AIM20846.1 - 0.16 12.2 1.7 1.4 9.1 0.1 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 AIM20846.1 - 0.18 11.1 1.1 2.2 7.5 0.2 2.2 2 0 0 2 2 2 0 Zeta toxin cobW PF02492.19 AIM20846.1 - 0.2 11.2 4.0 0.16 11.5 0.3 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.7 AIM20846.1 - 0.21 10.5 0.5 0.32 9.8 0.0 1.5 2 0 0 2 2 1 0 AAA-like domain MobB PF03205.14 AIM20846.1 - 0.26 11.2 0.5 0.66 9.9 0.1 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.12 AIM20846.1 - 0.47 10.3 3.3 0.62 10.0 0.2 2.5 2 0 0 2 2 2 0 NACHT domain HlyD_D23 PF16576.5 AIM20847.1 - 7.1e-17 61.3 4.9 7.4e-15 54.7 4.9 3.0 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AIM20847.1 - 3.8e-14 53.3 0.0 1.2e-10 42.0 0.0 2.6 2 0 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AIM20847.1 - 1.7e-12 47.0 0.1 1.7e-12 47.0 0.1 3.1 3 0 0 3 3 3 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AIM20847.1 - 0.0059 16.4 0.0 0.1 12.4 0.0 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme SpoIIIAH PF12685.7 AIM20847.1 - 0.035 14.0 3.3 0.075 12.9 3.3 1.5 1 1 0 1 1 1 0 SpoIIIAH-like protein Peptidase_M23 PF01551.22 AIM20847.1 - 0.047 13.9 0.0 0.3 11.3 0.0 2.1 2 0 0 2 2 2 0 Peptidase family M23 MT PF12777.7 AIM20847.1 - 0.16 11.0 8.6 0.19 10.7 0.2 2.6 2 1 1 3 3 3 0 Microtubule-binding stalk of dynein motor HemX PF04375.14 AIM20847.1 - 0.34 10.2 18.7 2.2 7.5 0.1 2.2 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF3584 PF12128.8 AIM20847.1 - 0.35 8.3 9.7 0.48 7.9 9.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4407 PF14362.6 AIM20847.1 - 1.5 8.1 13.1 2.6 7.3 13.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FliJ PF02050.16 AIM20847.1 - 5 7.4 25.1 7.8 6.8 13.8 2.5 1 1 1 2 2 2 0 Flagellar FliJ protein TetR_C_32 PF09209.11 AIM20848.1 - 1.4e-32 112.3 4.0 3e-32 111.2 3.1 1.9 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 AIM20848.1 - 7.1e-15 54.5 3.0 7.8e-15 54.4 0.8 2.1 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family DEAD PF00270.29 AIM20849.1 - 3.9e-50 170.0 0.0 8.6e-50 168.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AIM20849.1 - 9.7e-27 93.5 0.0 2.8e-26 92.0 0.0 1.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 AIM20849.1 - 8.9e-07 29.1 0.0 2.1e-06 27.9 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 AIM20849.1 - 1e-05 25.9 0.1 0.02 15.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain UTP25 PF06862.12 AIM20849.1 - 0.00023 20.1 0.0 0.81 8.4 0.0 3.4 2 1 1 3 3 3 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_22 PF13401.6 AIM20849.1 - 0.024 14.9 1.1 0.15 12.3 0.2 2.6 2 1 0 2 2 2 0 AAA domain UvrD-helicase PF00580.21 AIM20849.1 - 0.043 13.3 0.0 0.56 9.7 0.0 2.0 1 1 1 2 2 2 0 UvrD/REP helicase N-terminal domain 2-Hacid_dh_C PF02826.19 AIM20850.1 - 2.8e-53 179.9 0.0 4.4e-52 176.0 0.0 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 AIM20850.1 - 2.9e-12 46.4 0.0 3.7e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 AIM20850.1 - 2e-06 28.1 0.1 4.2e-06 27.0 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Dus PF01207.17 AIM20851.1 - 2.2e-88 296.3 0.0 2.7e-88 296.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 AIM20851.1 - 0.022 14.3 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein MR_MLE_C PF13378.6 AIM20851.1 - 0.062 12.8 0.1 0.12 11.9 0.1 1.6 1 1 0 1 1 1 0 Enolase C-terminal domain-like Bacillus_HBL PF05791.11 AIM20852.1 - 0.018 14.9 1.4 0.02 14.7 1.4 1.1 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) NYD-SP28 PF14772.6 AIM20852.1 - 0.028 14.4 2.9 0.035 14.1 2.9 1.1 1 0 0 1 1 1 0 Sperm tail Rx_N PF18052.1 AIM20852.1 - 0.067 13.5 0.5 1.3 9.3 0.1 2.1 2 0 0 2 2 2 0 Rx N-terminal domain NPV_P10 PF05531.12 AIM20852.1 - 0.1 13.1 1.5 0.52 10.8 0.1 2.0 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein ABC_tran PF00005.27 AIM20853.1 - 1.3e-36 126.1 0.0 2e-36 125.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter TOBE_2 PF08402.10 AIM20853.1 - 1.5e-10 41.1 0.2 6.4e-10 39.1 0.0 2.1 2 0 0 2 2 2 1 TOBE domain AAA_21 PF13304.6 AIM20853.1 - 2.1e-06 27.8 0.0 0.021 14.6 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system CysA_C_terminal PF17850.1 AIM20853.1 - 5.9e-06 26.8 0.6 1.5e-05 25.5 0.1 2.0 2 0 0 2 2 1 1 CysA C-terminal regulatory domain AAA PF00004.29 AIM20853.1 - 0.0001 22.7 0.1 0.00099 19.5 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AIM20853.1 - 0.00031 21.2 0.0 0.0005 20.5 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 AIM20853.1 - 0.0023 17.4 0.0 0.1 12.0 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_14 PF13173.6 AIM20853.1 - 0.0047 16.9 0.0 0.039 14.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain Rad17 PF03215.15 AIM20853.1 - 0.0059 16.5 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain RecA PF00154.21 AIM20853.1 - 0.0068 15.9 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 AIM20853.1 - 0.0072 15.9 0.1 0.14 11.7 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 AIM20853.1 - 0.0095 16.2 0.1 0.036 14.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 AIM20853.1 - 0.012 15.0 0.3 0.6 9.4 0.1 2.4 2 0 0 2 2 2 0 KaiC TniB PF05621.11 AIM20853.1 - 0.016 14.6 0.0 5.1 6.5 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein ATP-synt_ab PF00006.25 AIM20853.1 - 0.028 14.1 0.0 0.038 13.6 0.0 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain RsgA_GTPase PF03193.16 AIM20853.1 - 0.029 14.3 0.0 0.056 13.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase ABC_ATPase PF09818.9 AIM20853.1 - 0.033 13.0 0.3 0.36 9.6 0.0 2.5 2 1 0 2 2 2 0 Predicted ATPase of the ABC class AAA_29 PF13555.6 AIM20853.1 - 0.045 13.5 0.1 0.093 12.5 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 AIM20853.1 - 0.079 13.5 0.5 0.23 12.0 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 AIM20853.1 - 0.083 13.1 0.0 0.33 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain OB_MalK PF17912.1 AIM20853.1 - 0.092 13.6 0.0 0.76 10.7 0.0 2.5 2 0 0 2 2 2 0 MalK OB fold domain AAA_5 PF07728.14 AIM20853.1 - 0.094 12.7 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) G-alpha PF00503.20 AIM20853.1 - 0.099 11.8 0.0 0.62 9.2 0.0 1.8 2 0 0 2 2 2 0 G-protein alpha subunit AAA_24 PF13479.6 AIM20853.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AIM20853.1 - 0.14 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 AIM20853.1 - 0.21 11.3 0.0 3.5 7.2 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain BPD_transp_1 PF00528.22 AIM20854.1 - 1.3e-26 93.5 41.0 4.6e-17 62.3 16.8 4.2 4 1 1 5 5 5 2 Binding-protein-dependent transport system inner membrane component SBP_bac_6 PF13343.6 AIM20855.1 - 6.1e-34 117.5 0.2 7.4e-34 117.2 0.2 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 AIM20855.1 - 1.1e-23 84.4 4.5 1.5e-23 84.0 4.5 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 AIM20855.1 - 1.4e-19 70.8 0.1 2e-19 70.3 0.1 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AIM20855.1 - 8.9e-11 42.3 2.4 1.2e-10 41.9 2.4 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein DUF4354 PF14263.6 AIM20855.1 - 0.051 13.4 0.0 0.098 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4354) MFS_1 PF07690.16 AIM20856.1 - 3.8e-44 151.1 39.5 3.8e-44 151.1 39.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PTR2 PF00854.21 AIM20856.1 - 0.87 8.4 6.6 0.053 12.4 0.9 1.8 2 0 0 2 2 2 0 POT family MASE1 PF05231.14 AIM20857.1 - 5.6e-42 143.9 42.3 7.2e-42 143.6 42.3 1.1 1 0 0 1 1 1 1 MASE1 HisKA_3 PF07730.13 AIM20857.1 - 1.8e-14 54.0 5.4 1.8e-14 54.0 5.4 2.2 2 0 0 2 2 2 1 Histidine kinase HATPase_c PF02518.26 AIM20857.1 - 2.8e-08 34.3 0.1 5.9e-07 30.0 0.1 2.8 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ufd2P_core PF10408.9 AIM20857.1 - 0.055 12.1 0.2 0.081 11.5 0.2 1.1 1 0 0 1 1 1 0 Ubiquitin elongating factor core HATPase_c_3 PF13589.6 AIM20857.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AIM20858.1 - 2.1e-24 85.8 0.0 2.9e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AIM20858.1 - 6e-20 70.5 0.0 9e-20 70.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AIM20858.1 - 1.9e-07 30.6 0.0 3.5e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AIM20858.1 - 6.5e-06 25.6 0.0 1.6e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 AIM20858.1 - 0.0006 19.5 0.0 0.0013 18.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Acetyltransf_2 PF00797.17 AIM20859.1 - 7.1e-69 232.2 0.0 8.5e-69 232.0 0.0 1.1 1 0 0 1 1 1 1 N-acetyltransferase Transglut_core PF01841.19 AIM20859.1 - 0.0046 17.4 0.0 0.01 16.3 0.0 1.6 2 0 0 2 2 2 1 Transglutaminase-like superfamily Peptidase_C71 PF12386.8 AIM20859.1 - 0.053 13.2 0.0 0.082 12.5 0.0 1.3 1 0 0 1 1 1 0 Pseudomurein endo-isopeptidase Pei Polysacc_synt_3 PF13440.6 AIM20860.1 - 2.8e-11 43.2 15.9 2.8e-11 43.2 15.9 1.9 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein Polysacc_synt PF01943.17 AIM20860.1 - 5.5e-10 39.1 22.0 5.5e-10 39.1 22.0 2.9 1 1 2 3 3 3 1 Polysaccharide biosynthesis protein Polysacc_synt_C PF14667.6 AIM20860.1 - 1.3e-05 25.3 9.4 1.3e-05 25.3 9.4 4.1 2 1 2 4 4 4 1 Polysaccharide biosynthesis C-terminal domain ATPgrasp_TupA PF14305.6 AIM20861.1 - 3.8e-42 144.7 0.1 4.2e-42 144.6 0.1 1.0 1 0 0 1 1 1 1 TupA-like ATPgrasp LysR_substrate PF03466.20 AIM20862.1 - 8.9e-29 100.3 4.4 1.4e-28 99.7 4.4 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM20862.1 - 3.4e-17 62.1 5.3 3.4e-17 62.1 5.3 1.8 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family 2OG-FeII_Oxy_3 PF13640.6 AIM20863.1 - 8.2e-07 29.8 0.0 1.8e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TauD PF02668.16 AIM20863.1 - 7.2e-05 22.7 1.7 0.008 16.0 0.0 2.9 2 1 1 3 3 3 1 Taurine catabolism dioxygenase TauD, TfdA family PhyH PF05721.13 AIM20863.1 - 0.0018 18.6 0.0 1.1 9.5 0.0 2.2 2 0 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 AIM20863.1 - 0.0092 16.4 0.0 0.019 15.4 0.0 1.6 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase AA_permease PF00324.21 AIM20864.1 - 3.2e-125 418.5 39.5 3.8e-125 418.2 39.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 AIM20864.1 - 2.5e-42 145.2 47.0 3e-42 144.9 47.0 1.0 1 0 0 1 1 1 1 Amino acid permease DUF4307 PF14155.6 AIM20864.1 - 7.7 6.4 0.0 7.7 6.4 0.0 4.2 4 1 1 5 5 5 0 Domain of unknown function (DUF4307) BTP PF05232.12 AIM20865.1 - 6.9e-44 147.8 11.2 9.4e-25 86.5 5.6 2.0 2 0 0 2 2 2 2 Chlorhexidine efflux transporter GtrA PF04138.14 AIM20865.1 - 0.07 13.4 8.2 0.099 12.9 8.2 1.3 1 0 0 1 1 1 0 GtrA-like protein RseC_MucC PF04246.12 AIM20865.1 - 2 8.4 9.4 0.45 10.5 4.7 2.0 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC S_4TM PF18159.1 AIM20865.1 - 3.4 6.9 10.4 0.32 10.3 0.3 2.0 1 1 1 2 2 2 0 SMODS-associating 4TM effector domain LysR_substrate PF03466.20 AIM20866.1 - 1.1e-28 100.0 1.6 1.1e-28 100.0 1.6 1.8 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AIM20866.1 - 8.5e-17 60.9 0.2 1.9e-16 59.7 0.2 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family SNARE_assoc PF09335.11 AIM20867.1 - 1.4e-16 61.1 5.1 1.4e-16 61.1 5.1 1.7 2 1 0 2 2 2 1 SNARE associated Golgi protein BatA PF07584.11 AIM20867.1 - 0.036 14.4 1.6 3.2 8.2 0.4 2.6 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal PHO4 PF01384.20 AIM20867.1 - 0.58 9.1 2.5 0.42 9.6 0.3 1.7 2 0 0 2 2 2 0 Phosphate transporter family FixS PF03597.15 AIM20867.1 - 8.4 6.2 7.3 4.5 7.1 1.9 2.7 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type DJ-1_PfpI PF01965.24 AIM20868.1 - 9.6e-27 93.8 0.0 1.3e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.14 AIM20868.1 - 0.067 12.8 0.0 0.084 12.5 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 AIM20869.1 - 1.4e-23 83.5 0.0 1.9e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family HTH_18 PF12833.7 AIM20869.1 - 1e-21 77.0 0.3 2.3e-21 75.8 0.3 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AIM20869.1 - 5.2e-15 55.1 0.0 9.8e-08 31.9 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_31 PF13560.6 AIM20869.1 - 0.072 13.4 3.4 2.1 8.7 3.4 3.0 1 1 0 1 1 1 0 Helix-turn-helix domain DUF2065 PF09838.9 AIM20869.1 - 0.21 11.7 1.6 0.61 10.1 0.2 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2065) Patatin PF01734.22 AIM20869.1 - 5.9 7.0 7.1 10 6.2 7.1 1.6 1 1 0 1 1 1 0 Patatin-like phospholipase AdoHcyase_NAD PF00670.21 AIM20870.1 - 4.4e-34 117.9 0.0 7.3e-34 117.2 0.0 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AdoHcyase PF05221.17 AIM20870.1 - 3.6e-10 39.5 0.0 5.3e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase 2-Hacid_dh_C PF02826.19 AIM20870.1 - 4.2e-10 39.3 0.1 8e-10 38.4 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 AIM20870.1 - 8.1e-07 28.8 0.9 1.5e-06 27.8 0.9 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Shikimate_DH PF01488.20 AIM20870.1 - 1.7e-05 24.9 0.1 9e-05 22.5 0.1 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 AIM20870.1 - 0.00035 19.9 1.1 0.00062 19.1 1.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 AIM20870.1 - 0.0005 20.3 0.3 0.0021 18.3 0.3 2.0 1 1 0 1 1 1 1 TrkA-N domain NAD_binding_7 PF13241.6 AIM20870.1 - 0.00078 19.8 0.3 0.0018 18.7 0.3 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding F420_oxidored PF03807.17 AIM20870.1 - 0.0015 19.1 0.7 0.003 18.1 0.7 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent THF_DHG_CYH_C PF02882.19 AIM20870.1 - 0.015 14.6 1.1 0.076 12.3 1.1 1.9 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 AIM20870.1 - 0.021 14.7 1.3 0.031 14.2 1.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1188 PF06690.11 AIM20870.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) Sacchrp_dh_NADP PF03435.18 AIM20870.1 - 0.13 12.5 0.5 0.25 11.6 0.5 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Peptidase_S11 PF00768.20 AIM20871.1 - 3.4e-80 269.0 1.0 4.2e-80 268.6 1.0 1.1 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Beta-lactamase2 PF13354.6 AIM20871.1 - 2.5e-09 37.1 0.2 3.3e-09 36.6 0.2 1.2 1 0 0 1 1 1 1 Beta-lactamase enzyme family Peptidase_S13 PF02113.15 AIM20871.1 - 1.6e-05 23.9 1.9 0.0018 17.1 0.3 2.1 2 0 0 2 2 2 2 D-Ala-D-Ala carboxypeptidase 3 (S13) family Beta-lactamase PF00144.24 AIM20871.1 - 0.0024 17.2 0.8 0.053 12.7 0.2 2.2 2 0 0 2 2 2 1 Beta-lactamase Acetyltransf_1 PF00583.25 AIM20872.1 - 1e-13 51.6 0.0 1.3e-13 51.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AIM20872.1 - 1.9e-06 28.2 0.0 3e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 AIM20872.1 - 0.00017 21.8 0.7 0.00029 21.0 0.6 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AIM20872.1 - 0.00088 19.2 0.0 0.0012 18.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AIM20872.1 - 0.0014 19.3 0.0 0.0018 18.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AIM20872.1 - 0.0073 16.4 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 AIM20872.1 - 0.0089 16.1 0.0 0.013 15.6 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AIM20872.1 - 0.081 12.9 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein 3-dmu-9_3-mt PF06983.13 AIM20873.1 - 5.6e-22 78.5 0.0 6.3e-22 78.3 0.0 1.0 1 0 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase Glyoxalase PF00903.25 AIM20873.1 - 0.00031 20.9 0.0 0.0007 19.8 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Hydrolase_4 PF12146.8 AIM20874.1 - 5e-26 91.4 0.2 4.1e-25 88.5 0.2 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AIM20874.1 - 1.1e-11 44.9 0.0 3.2e-09 36.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF3530 PF12048.8 AIM20874.1 - 0.054 12.9 0.1 0.12 11.7 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) DUF915 PF06028.11 AIM20874.1 - 0.061 12.7 0.0 0.091 12.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Peptidase_S15 PF02129.18 AIM20874.1 - 0.11 12.1 0.0 13 5.3 0.0 2.2 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF808 PF05661.12 AIM20875.1 - 3.6e-117 390.8 7.7 4.1e-117 390.6 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF808) Acetyltransf_4 PF13420.7 AIM20876.1 - 5.3e-15 55.9 0.0 6.4e-15 55.6 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AIM20876.1 - 1.1e-11 45.0 0.0 1.4e-11 44.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AIM20876.1 - 1.1e-07 32.1 0.0 1.7e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AIM20876.1 - 9.5e-07 29.6 0.0 1.2e-06 29.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AIM20876.1 - 8.6e-05 22.5 0.0 0.00012 22.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AIM20876.1 - 0.012 15.5 0.0 0.028 14.4 0.0 1.5 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_8 PF13523.6 AIM20876.1 - 0.039 13.7 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 AIM20876.1 - 0.09 12.3 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase Lipoprotein_9 PF03180.14 AIM20877.1 - 6.6e-91 303.6 0.0 7.5e-91 303.4 0.0 1.0 1 0 0 1 1 1 1 NLPA lipoprotein OpuAC PF04069.12 AIM20877.1 - 0.0021 17.7 0.0 0.0076 15.9 0.0 1.8 2 0 0 2 2 2 1 Substrate binding domain of ABC-type glycine betaine transport system DUF1460 PF07313.12 AIM20878.1 - 3.1e-76 255.5 0.0 4e-76 255.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1460) Acetyltransf_1 PF00583.25 AIM20879.1 - 9.4e-18 64.6 0.0 1.2e-17 64.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AIM20879.1 - 4.2e-12 46.1 0.0 5.9e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AIM20879.1 - 6.1e-10 39.4 0.0 8.5e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AIM20879.1 - 0.0018 18.4 0.0 0.003 17.7 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 AIM20879.1 - 0.0019 18.1 0.0 0.0034 17.3 0.0 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_3 PF13302.7 AIM20879.1 - 0.0032 18.1 0.0 0.0043 17.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AIM20879.1 - 0.016 15.4 0.0 0.022 14.9 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 AIM20879.1 - 0.018 15.0 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_8 PF13523.6 AIM20879.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Hexapep PF00132.24 AIM20880.1 - 6.8e-15 54.1 11.6 5.8e-07 29.0 0.0 4.5 3 2 2 5 5 5 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AIM20880.1 - 3.2e-09 36.4 12.6 1.5e-05 24.6 3.8 3.8 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 AIM20880.1 - 0.36 8.9 0.3 31 2.5 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4954) DUF1282 PF06930.12 AIM20881.1 - 1.3e-37 129.2 6.0 1.6e-37 128.9 6.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) Yip1 PF04893.17 AIM20881.1 - 1e-31 110.0 8.6 1e-31 110.0 8.6 1.5 1 1 1 2 2 2 1 Yip1 domain Bac_export_2 PF01312.19 AIM20881.1 - 1.2 8.3 2.9 0.78 8.9 1.5 1.5 2 0 0 2 2 2 0 FlhB HrpN YscU SpaS Family Imm_superinfect PF14373.6 AIM20881.1 - 1.4 8.9 10.4 0.72 9.8 0.9 3.0 3 0 0 3 3 3 0 Superinfection immunity protein DUF2070 PF09843.9 AIM20881.1 - 4.9 5.3 6.5 6 5.0 6.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) EamA PF00892.20 AIM20882.1 - 2.1e-21 76.5 36.3 7.7e-14 52.0 15.8 2.3 2 1 0 2 2 2 2 EamA-like transporter family ABC_tran PF00005.27 AIM20883.1 - 3.9e-32 111.6 0.0 5.2e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIM20883.1 - 1.1e-10 41.9 2.1 0.0002 21.3 0.1 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIM20883.1 - 4.6e-06 26.2 0.3 0.015 14.8 0.2 2.4 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AIM20883.1 - 0.00025 21.5 0.7 0.00043 20.7 0.7 1.4 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AIM20883.1 - 0.0033 17.3 0.2 0.013 15.4 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 AIM20883.1 - 0.0036 17.0 0.3 0.0089 15.8 0.1 1.7 1 1 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AIM20883.1 - 0.0043 17.3 0.0 0.026 14.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 AIM20883.1 - 0.016 15.5 0.0 0.077 13.2 0.0 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 AIM20883.1 - 0.025 14.7 0.0 0.048 13.7 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_15 PF13175.6 AIM20883.1 - 0.028 14.1 0.0 0.082 12.6 0.1 1.6 2 0 0 2 2 2 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 AIM20883.1 - 0.034 13.5 0.1 0.05 12.9 0.1 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family Dynamin_N PF00350.23 AIM20883.1 - 0.038 14.0 0.0 0.065 13.3 0.0 1.3 1 0 0 1 1 1 0 Dynamin family AAA_33 PF13671.6 AIM20883.1 - 0.04 14.1 0.0 0.79 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 AIM20883.1 - 0.056 13.1 0.0 0.074 12.7 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.22 AIM20883.1 - 0.068 13.6 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.6 AIM20883.1 - 0.089 13.3 0.1 0.13 12.7 0.1 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 AIM20883.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 NACHT domain Roc PF08477.13 AIM20883.1 - 0.14 12.4 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 AIM20883.1 - 0.21 11.3 0.0 0.32 10.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain Adeno_IVa2 PF02456.15 AIM20883.1 - 0.26 10.0 0.0 0.42 9.3 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein Peripla_BP_2 PF01497.18 AIM20884.1 - 7.9e-21 74.7 0.0 1.1e-20 74.2 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein FecCD PF01032.18 AIM20885.1 - 1.1e-80 270.9 34.6 1.4e-80 270.7 34.6 1.0 1 0 0 1 1 1 1 FecCD transport family Peptidase_U4 PF03419.13 AIM20885.1 - 1.7 7.8 15.3 0.022 14.0 5.8 2.3 1 1 1 2 2 2 0 Sporulation factor SpoIIGA Flavodoxin_1 PF00258.25 AIM20886.1 - 3.3e-23 82.5 0.0 5.3e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 AIM20886.1 - 3.9e-15 56.4 0.0 7.5e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_1 PF00667.20 AIM20886.1 - 2.8e-14 53.2 0.0 5.7e-07 29.3 0.0 2.2 1 1 1 2 2 2 2 FAD binding domain DUF72 PF01904.18 AIM20886.1 - 0.046 13.8 0.0 0.099 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF72 PAS PF00989.25 AIM20887.1 - 4.7e-12 45.9 0.0 5.9e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 AIM20887.1 - 6e-12 45.7 0.0 8.3e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AIM20887.1 - 2.1e-11 44.0 0.0 2.7e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 AIM20887.1 - 2.3e-05 24.6 0.0 3.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 AIM20887.1 - 5.5e-05 23.1 0.0 0.00017 21.5 0.0 1.8 2 1 0 2 2 2 1 PAS domain Lact-deh-memb PF09330.11 AIM20888.1 - 4.1e-150 498.9 0.6 5.2e-150 498.6 0.6 1.1 1 0 0 1 1 1 1 D-lactate dehydrogenase, membrane binding FAD_binding_4 PF01565.23 AIM20888.1 - 3.1e-09 36.7 0.1 5.3e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Herpes_glycop PF01528.16 AIM20888.1 - 0.19 10.5 0.0 0.29 10.0 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus glycoprotein M Peptidase_M24 PF00557.24 AIM20889.1 - 9.3e-49 165.9 0.3 1.1e-48 165.8 0.3 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 ParD_like PF11903.8 AIM20890.1 - 1.5e-21 76.3 0.0 1.5e-21 76.2 0.0 1.0 1 0 0 1 1 1 1 ParD-like antitoxin of type II bacterial toxin-antitoxin system Dala_Dala_lig_C PF07478.13 AIM20891.1 - 1.9e-79 266.0 0.0 2.5e-79 265.6 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Dala_Dala_lig_N PF01820.21 AIM20891.1 - 6.6e-30 103.6 0.0 1.1e-29 102.9 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase N-terminus ATP-grasp PF02222.22 AIM20891.1 - 8e-13 48.3 0.0 1.7e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 AIM20891.1 - 1.1e-07 31.6 0.0 1.7e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.6 AIM20891.1 - 2e-05 24.3 0.2 0.00028 20.5 0.2 2.3 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 AIM20891.1 - 0.002 17.4 0.0 0.42 9.8 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp RimK PF08443.11 AIM20891.1 - 0.0048 16.5 0.0 0.014 15.0 0.0 1.7 2 0 0 2 2 2 1 RimK-like ATP-grasp domain SBP_bac_3 PF00497.20 AIM20892.1 - 4.9e-53 179.9 0.1 5.6e-53 179.7 0.1 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1 PF09084.11 AIM20892.1 - 9e-05 22.5 0.0 0.00064 19.7 0.0 2.0 1 1 1 2 2 2 1 NMT1/THI5 like Lig_chan-Glu_bd PF10613.9 AIM20892.1 - 0.034 14.3 0.0 0.078 13.2 0.0 1.7 1 1 0 1 1 1 0 Ligated ion channel L-glutamate- and glycine-binding site Aminotran_1_2 PF00155.21 AIM20893.1 - 2.9e-62 210.9 0.0 3.3e-62 210.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 AIM20893.1 - 1.6e-09 37.6 0.2 2.5e-09 36.9 0.2 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 AIM20893.1 - 1.4e-07 30.4 0.2 4e-07 28.9 0.2 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 AIM20893.1 - 2.8e-06 26.6 0.0 3.9e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 AIM20893.1 - 0.00013 21.4 0.1 0.00019 20.8 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_MocR PF12897.7 AIM20893.1 - 0.011 14.5 0.2 0.02 13.7 0.2 1.5 1 1 0 1 1 1 0 Alanine-glyoxylate amino-transferase Foie-gras_1 PF11817.8 AIM20893.1 - 0.013 15.1 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Foie gras liver health family 1 LysR_substrate PF03466.20 AIM20894.1 - 3.1e-30 105.1 2.3 4.3e-30 104.6 2.3 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM20894.1 - 1.6e-19 69.6 1.0 3.8e-19 68.4 1.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family hNIFK_binding PF12196.8 AIM20894.1 - 0.023 14.2 2.0 0.044 13.3 2.0 1.4 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK Glyco_hydro_3 PF00933.21 AIM20895.1 - 2.5e-88 296.5 0.0 3.4e-88 296.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 AIM20895.1 - 1e-63 215.0 0.1 1.6e-63 214.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 AIM20895.1 - 5.7e-21 74.4 0.1 1.1e-20 73.5 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PHP PF02811.19 AIM20895.1 - 0.041 14.2 0.0 0.076 13.3 0.0 1.4 1 0 0 1 1 1 0 PHP domain YAcAr PF10686.9 AIM20896.1 - 0.0052 16.7 0.7 0.02 14.8 0.1 2.2 2 0 0 2 2 2 1 YspA, cpYpsA-related SLOG family baeRF_family2 PF18844.1 AIM20896.1 - 0.046 13.8 0.2 1.3 9.1 0.1 2.6 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 2 FidL_like PF15941.5 AIM20897.1 - 0.0081 16.6 0.0 0.012 16.0 0.0 1.3 1 0 0 1 1 1 1 FidL-like putative membrane protein Trans_reg_C PF00486.28 AIM20898.1 - 5.4e-12 45.6 0.0 1.1e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Wzy_C PF04932.15 AIM20899.1 - 0.00047 19.8 0.0 0.00047 19.8 0.0 4.3 2 1 1 3 3 3 1 O-Antigen ligase stn_TNFRSF12A PF12191.8 AIM20899.1 - 0.018 15.3 3.0 0.079 13.2 3.0 2.2 1 1 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain GerE PF00196.19 AIM20900.1 - 3.2e-14 52.2 0.0 5.8e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4 PF04545.16 AIM20900.1 - 0.0016 18.0 0.0 0.0031 17.0 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 MarR_2 PF12802.7 AIM20900.1 - 0.029 14.3 0.0 0.068 13.1 0.0 1.6 1 0 0 1 1 1 0 MarR family HTH_20 PF12840.7 AIM20900.1 - 0.054 13.6 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_38 PF13936.6 AIM20900.1 - 0.061 13.1 0.0 0.18 11.6 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 AIM20900.1 - 7.6 6.5 7.7 0.89 9.4 0.2 3.0 3 1 0 3 3 3 0 Homeodomain-like domain Abhydrolase_1 PF00561.20 AIM20901.1 - 3e-22 79.5 0.0 1e-17 64.7 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AIM20901.1 - 7.4e-16 59.4 4.9 9.7e-16 59.0 4.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AIM20901.1 - 0.00011 21.6 0.0 0.0027 17.0 0.0 2.1 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 AIM20901.1 - 0.004 16.7 0.0 1.5 8.3 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 AIM20901.1 - 0.021 15.0 0.0 0.037 14.2 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Abhydrolase_5 PF12695.7 AIM20901.1 - 0.078 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 AIM20901.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Ndr PF03096.14 AIM20901.1 - 0.14 10.8 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Ndr family CDH PF02611.15 AIM20902.1 - 6.4e-84 281.0 0.1 7.3e-84 280.9 0.1 1.0 1 0 0 1 1 1 1 CDP-diacylglycerol pyrophosphatase HIT PF01230.23 AIM20902.1 - 0.029 15.1 0.0 0.054 14.2 0.0 1.5 1 0 0 1 1 1 0 HIT domain DUF4307 PF14155.6 AIM20902.1 - 0.17 11.7 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) RHH_1 PF01402.21 AIM20903.1 - 0.055 13.4 0.4 2.4 8.2 0.4 2.5 1 1 0 1 1 1 0 Ribbon-helix-helix protein, copG family AAA_31 PF13614.6 AIM20904.1 - 2.2e-16 60.3 1.2 1.4e-08 34.8 1.1 2.2 1 1 1 2 2 2 2 AAA domain MipZ PF09140.11 AIM20904.1 - 2.9e-15 56.3 0.2 2.6e-07 30.2 0.0 2.9 2 1 1 3 3 3 2 ATPase MipZ CbiA PF01656.23 AIM20904.1 - 6.6e-10 39.1 0.0 8.3e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain VirC1 PF07015.11 AIM20904.1 - 2.7e-07 30.2 0.0 4.3e-07 29.5 0.0 1.3 1 1 0 1 1 1 1 VirC1 protein ParA PF10609.9 AIM20904.1 - 1.3e-06 28.0 0.2 3.2e-06 26.8 0.2 1.7 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 AIM20904.1 - 6.5e-05 22.7 0.3 0.00014 21.6 0.3 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ArsA_ATPase PF02374.15 AIM20904.1 - 0.0034 16.6 2.6 0.035 13.3 0.3 2.4 2 1 1 3 3 3 1 Anion-transporting ATPase Fer4_NifH PF00142.18 AIM20904.1 - 0.065 12.7 0.2 0.25 10.7 0.1 1.9 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 AIM20904.1 - 0.068 12.6 0.0 3.6 7.0 0.0 2.3 1 1 1 2 2 2 0 Cellulose biosynthesis protein BcsQ CLP1_P PF16575.5 AIM20904.1 - 0.14 12.0 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop HNH PF01844.23 AIM20905.1 - 7.4e-12 45.2 8.3 1e-11 44.8 8.3 1.2 1 0 0 1 1 1 1 HNH endonuclease Ima1_N PF09779.9 AIM20905.1 - 0.051 14.4 0.5 10 7.0 0.0 2.1 2 0 0 2 2 2 0 Ima1 N-terminal domain Endonuclease_7 PF02945.15 AIM20905.1 - 2.9 7.9 7.2 5.6 7.0 7.3 1.5 1 1 0 1 1 1 0 Recombination endonuclease VII LysR_substrate PF03466.20 AIM20906.1 - 1.6e-44 151.8 0.8 2e-44 151.4 0.8 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM20906.1 - 1.9e-18 66.2 0.3 3.3e-18 65.4 0.3 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_IclR PF09339.10 AIM20906.1 - 0.0018 18.0 0.0 0.0043 16.8 0.0 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain MFS_1 PF07690.16 AIM20907.1 - 3.1e-29 102.0 56.5 3.1e-29 102.0 56.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 AIM20907.1 - 8.3e-09 34.8 11.1 8.3e-09 34.8 11.1 3.1 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 AIM20907.1 - 0.00047 19.1 5.8 0.00047 19.1 5.8 2.2 2 0 0 2 2 2 2 MFS_1 like family MFS_4 PF06779.14 AIM20907.1 - 0.024 14.0 37.0 0.032 13.5 37.0 1.1 1 0 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB FGGY_N PF00370.21 AIM20908.1 - 4.9e-51 173.7 0.0 1.1e-50 172.5 0.0 1.7 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 AIM20908.1 - 1.3e-17 64.2 0.2 2.1e-17 63.5 0.2 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain ABM PF03992.16 AIM20909.1 - 4e-18 65.3 0.1 4.6e-18 65.1 0.1 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase EamA PF00892.20 AIM20910.1 - 2.4e-31 108.8 42.8 1.2e-15 57.8 17.7 2.1 2 0 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 AIM20910.1 - 0.00011 21.3 4.3 0.0018 17.3 2.5 2.1 2 0 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like UAA PF08449.11 AIM20910.1 - 0.69 9.1 10.4 8.8 5.4 10.3 2.1 1 1 0 1 1 1 0 UAA transporter family LysE PF01810.18 AIM20911.1 - 8.3e-19 67.8 13.9 1.1e-18 67.5 13.9 1.1 1 0 0 1 1 1 1 LysE type translocator FtsX PF02687.21 AIM20911.1 - 0.44 11.1 7.5 3.9 8.0 7.5 2.3 1 1 0 1 1 1 0 FtsX-like permease family CPP1-like PF11833.8 AIM20911.1 - 5.6 6.6 9.6 1.5 8.4 6.2 1.8 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like HTH_AraC PF00165.23 AIM20912.1 - 1.5e-21 75.9 0.1 2.7e-13 49.6 0.0 2.3 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 AIM20912.1 - 2.6e-21 75.7 0.6 4e-21 75.1 0.6 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain AraC_binding PF02311.19 AIM20912.1 - 3.4e-18 65.8 0.1 9.7e-18 64.4 0.0 1.7 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_2 PF07883.11 AIM20912.1 - 0.0013 18.4 0.0 0.0031 17.2 0.0 1.6 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 AIM20912.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) DUF4898 PF16239.5 AIM20913.1 - 0.16 11.9 0.0 0.19 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4898) RIO1 PF01163.22 AIM20914.1 - 6.8e-40 136.7 0.0 9.2e-40 136.2 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 AIM20914.1 - 9.8e-05 22.4 1.8 0.0013 18.7 1.8 2.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 AIM20914.1 - 0.0033 17.0 0.3 0.061 12.8 0.0 2.2 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Alpha-amylase PF00128.24 AIM20915.1 - 4.5e-24 85.6 0.1 1.1e-23 84.3 0.1 1.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 AIM20915.1 - 1.9e-08 33.0 0.1 0.0018 16.6 0.0 3.2 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 Alpha-amylase_C PF02806.18 AIM20915.1 - 0.00013 22.4 0.0 0.00049 20.5 0.0 2.0 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain DUF1939 PF09154.10 AIM20915.1 - 0.0046 17.1 0.0 0.013 15.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1939) MarR_2 PF12802.7 AIM20916.1 - 4.8e-12 45.6 3.7 3.6e-11 42.8 0.2 2.9 3 0 0 3 3 3 1 MarR family Acetyltransf_1 PF00583.25 AIM20916.1 - 5.3e-12 46.0 0.2 9.9e-12 45.1 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family MarR PF01047.22 AIM20916.1 - 1e-09 38.2 0.0 2.4e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 MarR family Acetyltransf_7 PF13508.7 AIM20916.1 - 5.5e-08 33.1 0.5 1e-07 32.3 0.5 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AIM20916.1 - 6.4e-07 29.4 0.0 1.9e-06 27.9 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain HTH_IclR PF09339.10 AIM20916.1 - 5.6e-06 26.1 0.1 1.7e-05 24.5 0.1 1.9 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_27 PF13463.6 AIM20916.1 - 6.9e-06 26.5 0.2 2.9e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_20 PF12840.7 AIM20916.1 - 0.00015 21.8 0.3 0.00061 19.8 0.1 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain TrmB PF01978.19 AIM20916.1 - 0.00067 19.5 0.0 0.0018 18.2 0.0 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB RP-C PF03428.13 AIM20916.1 - 0.0029 17.3 2.0 0.0095 15.6 2.0 1.9 1 1 0 1 1 1 1 Replication protein C N-terminal domain HTH_5 PF01022.20 AIM20916.1 - 0.003 17.4 0.1 0.0059 16.5 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family FR47 PF08445.10 AIM20916.1 - 0.0038 17.2 0.1 0.027 14.4 0.0 2.3 2 0 0 2 2 2 1 FR47-like protein HTH_Crp_2 PF13545.6 AIM20916.1 - 0.0064 16.4 0.4 0.035 14.1 0.0 2.4 3 0 0 3 3 2 1 Crp-like helix-turn-helix domain GntR PF00392.21 AIM20916.1 - 0.01 15.4 0.1 0.04 13.6 0.1 2.0 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family Rrf2 PF02082.20 AIM20916.1 - 0.012 16.0 0.3 0.045 14.1 0.0 2.0 2 0 0 2 2 2 0 Transcriptional regulator Fe_dep_repress PF01325.19 AIM20916.1 - 0.022 14.9 0.0 0.071 13.3 0.0 1.8 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_29 PF13551.6 AIM20916.1 - 0.045 13.8 0.0 0.17 11.9 0.0 2.0 1 0 0 1 1 1 0 Winged helix-turn helix Acetyltransf_9 PF13527.7 AIM20916.1 - 0.069 13.2 0.8 0.65 10.1 0.2 2.7 3 1 0 3 3 3 0 Acetyltransferase (GNAT) domain HTH_36 PF13730.6 AIM20916.1 - 0.08 12.9 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_CodY PF08222.11 AIM20916.1 - 0.096 12.3 0.5 1.1 8.8 0.1 2.2 2 0 0 2 2 2 0 CodY helix-turn-helix domain Acetyltransf_CG PF14542.6 AIM20916.1 - 0.11 12.7 0.1 0.44 10.7 0.0 1.9 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase HTH_24 PF13412.6 AIM20916.1 - 0.18 11.4 0.5 0.47 10.1 0.1 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Na_sulph_symp PF00939.19 AIM20917.1 - 5.1e-26 91.8 26.5 5.7e-26 91.6 26.5 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 AIM20917.1 - 1.1e-14 54.4 32.9 1.7e-14 53.7 32.9 1.2 1 0 0 1 1 1 1 Citrate transporter DAP_epimerase PF01678.19 AIM20918.1 - 9.1e-48 161.4 0.0 2.8e-23 82.4 0.0 2.1 2 0 0 2 2 2 2 Diaminopimelate epimerase DUF1471 PF07338.13 AIM20919.1 - 2.7e-18 65.7 0.5 3.9e-18 65.2 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1471) Sugarporin_N PF11471.8 AIM20919.1 - 0.29 11.1 2.9 12 5.9 0.0 2.3 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension DUF1471 PF07338.13 AIM20920.1 - 3.3e-19 68.6 0.4 4.7e-19 68.1 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1471) TetR_N PF00440.23 AIM20921.1 - 6.9e-13 48.2 0.2 1.4e-12 47.2 0.2 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_13 PF16925.5 AIM20921.1 - 8.5e-05 22.5 0.2 0.0012 18.8 0.0 2.1 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_11 PF16859.5 AIM20921.1 - 0.0001 22.6 1.1 0.0014 18.9 0.1 2.6 2 1 1 3 3 3 1 Tetracyclin repressor-like, C-terminal domain TetR_C_6 PF13977.6 AIM20921.1 - 0.00047 20.4 0.3 0.0012 19.0 0.3 1.7 1 0 0 1 1 1 1 BetI-type transcriptional repressor, C-terminal TetR_C_17 PF17922.1 AIM20921.1 - 0.0038 17.3 0.0 0.0077 16.3 0.0 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain PaaX PF07848.12 AIM20921.1 - 0.016 15.4 0.0 3.5 7.9 0.0 3.3 2 1 1 3 3 3 0 PaaX-like protein Lipoprotein_9 PF03180.14 AIM20922.1 - 1.2e-76 256.9 3.2 1.4e-76 256.7 3.2 1.0 1 0 0 1 1 1 1 NLPA lipoprotein BPD_transp_1 PF00528.22 AIM20923.1 - 3.7e-22 79.0 15.3 3.7e-22 79.0 15.3 1.8 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component Mt_ATP-synt_B PF05405.14 AIM20923.1 - 0.13 11.9 0.1 0.25 10.9 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF1772 PF08592.11 AIM20923.1 - 6.7 7.0 11.4 4.2e+02 1.2 11.4 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) ABC_tran PF00005.27 AIM20924.1 - 3.1e-34 118.4 0.0 7.8e-34 117.1 0.0 1.6 2 0 0 2 2 2 1 ABC transporter NIL PF09383.10 AIM20924.1 - 5.6e-16 58.1 0.2 1.1e-15 57.2 0.2 1.5 1 0 0 1 1 1 1 NIL domain AAA_21 PF13304.6 AIM20924.1 - 2.2e-06 27.7 0.6 0.028 14.2 0.0 2.6 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIM20924.1 - 4.3e-05 23.1 0.2 0.00016 21.2 0.2 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 AIM20924.1 - 0.002 18.1 0.3 0.005 16.7 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 AIM20924.1 - 0.0053 17.0 1.4 0.12 12.7 1.4 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AIM20924.1 - 0.012 16.1 0.7 0.051 14.0 0.7 2.1 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 AIM20924.1 - 0.012 15.7 0.0 0.031 14.3 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 AIM20924.1 - 0.012 15.3 0.1 0.027 14.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Phage_T7_Capsid PF05396.11 AIM20924.1 - 0.017 15.5 0.0 0.2 12.0 0.0 2.4 3 0 0 3 3 3 0 Phage T7 capsid assembly protein AAA_30 PF13604.6 AIM20924.1 - 0.11 12.2 0.3 0.6 9.8 0.1 2.4 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 AIM20924.1 - 0.22 12.0 0.1 0.4 11.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain Acetyltransf_10 PF13673.7 AIM20925.1 - 4.1e-16 59.1 0.0 4.8e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AIM20925.1 - 9.2e-14 51.6 0.0 1.3e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AIM20925.1 - 5.4e-09 36.3 0.0 6.5e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF2236 PF09995.9 AIM20926.1 - 5.3e-53 180.5 7.5 6.3e-53 180.3 7.5 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) 3HCDH_RFF PF18321.1 AIM20926.1 - 0.038 14.4 0.2 0.075 13.5 0.2 1.5 1 0 0 1 1 1 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain SUFU PF05076.13 AIM20927.1 - 2e-18 67.0 0.9 3.5e-17 62.9 0.0 2.4 3 0 0 3 3 3 2 Suppressor of fused protein (SUFU) Isochorismatase PF00857.20 AIM20928.1 - 5.1e-34 118.0 0.0 5.5e-34 117.9 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family FAD_binding_4 PF01565.23 AIM20928.1 - 0.02 14.6 0.2 0.19 11.5 0.0 2.4 2 1 1 3 3 3 0 FAD binding domain NAD_binding_2 PF03446.15 AIM20929.1 - 7.4e-38 130.2 0.4 1.3e-37 129.4 0.4 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 AIM20929.1 - 4.5e-15 56.0 2.2 8.7e-15 55.0 2.2 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 AIM20929.1 - 7.9e-11 41.6 0.1 1.1e-10 41.1 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 AIM20929.1 - 6.5e-05 23.4 0.4 0.00018 22.0 0.1 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 AIM20929.1 - 8.2e-05 22.3 0.0 0.00013 21.6 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 AIM20929.1 - 0.0017 18.4 0.0 0.0027 17.8 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 AIM20929.1 - 0.0073 15.9 0.1 0.015 14.8 0.1 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 AIM20929.1 - 0.0088 15.4 0.4 0.017 14.4 0.2 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 AIM20929.1 - 0.03 14.2 0.2 0.05 13.5 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.25 AIM20929.1 - 0.038 13.4 0.9 0.3 10.5 0.1 2.1 1 1 1 2 2 2 0 short chain dehydrogenase tRNA-synt_1b PF00579.25 AIM20930.1 - 1.6e-50 172.1 0.0 2.1e-50 171.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) ABC_tran PF00005.27 AIM20931.1 - 6.3e-31 107.7 0.0 1.2e-30 106.8 0.0 1.5 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.6 AIM20931.1 - 1.1e-07 32.0 0.0 0.00081 19.3 0.0 2.4 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 AIM20931.1 - 7.7e-06 25.9 0.1 6.2e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 AIM20931.1 - 9.7e-05 21.9 0.2 0.0016 17.9 0.2 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 AIM20931.1 - 0.00099 19.2 0.0 0.012 15.7 0.0 2.5 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_29 PF13555.6 AIM20931.1 - 0.001 18.8 0.0 0.0028 17.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AIM20931.1 - 0.0016 18.9 2.0 0.013 15.9 2.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain KdpD PF02702.17 AIM20931.1 - 0.0019 17.7 0.0 0.0029 17.1 0.0 1.3 1 0 0 1 1 1 1 Osmosensitive K+ channel His kinase sensor domain AAA_15 PF13175.6 AIM20931.1 - 0.0035 17.1 0.0 2.5 7.7 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 AIM20931.1 - 0.0045 17.3 0.7 0.021 15.1 0.6 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AIM20931.1 - 0.029 14.9 0.1 3.2 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 AIM20931.1 - 0.03 13.7 0.1 0.092 12.1 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_25 PF13481.6 AIM20931.1 - 0.074 12.6 0.2 0.18 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 AIM20931.1 - 0.079 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.12 AIM20931.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 NACHT domain SbcCD_C PF13558.6 AIM20931.1 - 0.11 12.7 0.0 0.83 9.9 0.0 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Cellulase PF00150.18 AIM20931.1 - 0.16 11.4 0.0 0.22 10.9 0.0 1.1 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) AAA_23 PF13476.6 AIM20931.1 - 0.23 11.9 0.0 0.39 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Phosphonate-bd PF12974.7 AIM20932.1 - 1.9e-47 161.9 0.0 2.3e-47 161.7 0.0 1.1 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 AIM20932.1 - 0.0061 16.0 0.0 0.034 13.6 0.0 2.0 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1 PF09084.11 AIM20932.1 - 0.012 15.6 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 NMT1/THI5 like BPD_transp_1 PF00528.22 AIM20933.1 - 8.7e-15 54.9 9.3 8.7e-15 54.9 9.3 1.7 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 AIM20934.1 - 1.3e-06 28.3 7.1 1.3e-06 28.3 7.1 2.2 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF1456 PF07308.13 AIM20935.1 - 5.4e-54 180.4 0.5 7.8e-26 90.2 0.1 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF1456) DUF1177 PF06675.11 AIM20935.1 - 0.19 10.5 0.1 0.26 10.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1177) Mucin_bdg PF03272.13 AIM20936.1 - 5.7e-58 194.0 0.0 1e-29 102.9 0.0 2.5 2 0 0 2 2 2 2 Putative mucin or carbohydrate-binding module Peptidase_M60 PF13402.6 AIM20936.1 - 1.4e-14 54.3 0.3 2e-14 53.8 0.3 1.2 1 0 0 1 1 1 1 Peptidase M60, enhancin and enhancin-like Amidase PF01425.21 AIM20937.1 - 8.6e-88 295.3 0.2 1.3e-87 294.6 0.2 1.2 1 0 0 1 1 1 1 Amidase CT_A_B PF02626.15 AIM20938.1 - 1.6e-94 316.4 0.0 3e-94 315.6 0.0 1.5 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 AIM20938.1 - 5e-62 209.1 0.0 9.2e-62 208.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CT_C_D PF02682.16 AIM20938.1 - 1.8e-46 158.4 0.0 4.8e-46 157.1 0.0 1.7 2 0 0 2 2 2 1 Carboxyltransferase domain, subdomain C and D Biotin_carb_N PF00289.22 AIM20938.1 - 8.6e-43 145.4 0.4 1.7e-42 144.4 0.4 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 AIM20938.1 - 2.8e-36 123.9 0.0 6.8e-36 122.7 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 AIM20938.1 - 6.2e-16 58.0 0.0 1.6e-15 56.7 0.0 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 AIM20938.1 - 2.6e-10 40.2 0.0 5e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 AIM20938.1 - 7e-07 29.0 0.0 0.0029 17.4 0.1 3.0 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.22 AIM20938.1 - 0.00037 20.1 0.0 0.00076 19.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 AIM20938.1 - 0.00055 20.6 0.3 1.3 9.8 0.0 3.2 3 1 1 4 4 2 2 HlyD family secretion protein ATP-grasp_5 PF13549.6 AIM20938.1 - 0.00068 19.2 0.0 0.0018 17.8 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain HlyD_D23 PF16576.5 AIM20938.1 - 0.0055 15.9 0.0 1.5 8.0 0.0 2.4 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion RimK PF08443.11 AIM20938.1 - 0.0071 16.0 0.0 0.015 14.9 0.0 1.5 1 1 0 1 1 1 1 RimK-like ATP-grasp domain RnfC_N PF13375.6 AIM20938.1 - 0.032 14.2 0.0 0.084 12.8 0.0 1.6 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain NQRA PF05896.11 AIM20938.1 - 0.099 12.1 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) DUF2190 PF09956.9 AIM20938.1 - 0.41 11.2 2.8 0.52 10.8 0.0 2.7 3 0 0 3 3 1 0 Uncharacterized conserved protein (DUF2190) FCD PF07729.12 AIM20939.1 - 4.6e-21 75.5 8.6 8.3e-21 74.7 8.6 1.4 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 AIM20939.1 - 1.1e-15 57.0 0.2 3.4e-15 55.5 0.0 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_24 PF13412.6 AIM20939.1 - 0.00022 20.7 0.1 0.0057 16.2 0.0 2.7 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Fe_dep_repress PF01325.19 AIM20939.1 - 0.00072 19.7 0.0 0.0032 17.6 0.0 2.1 2 0 0 2 2 2 1 Iron dependent repressor, N-terminal DNA binding domain HTH_IclR PF09339.10 AIM20939.1 - 0.011 15.6 2.3 0.58 10.0 0.0 2.5 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_27 PF13463.6 AIM20939.1 - 0.058 13.9 0.0 0.57 10.7 0.0 2.5 2 0 0 2 2 2 0 Winged helix DNA-binding domain TrmB PF01978.19 AIM20939.1 - 0.13 12.2 0.0 0.55 10.2 0.0 2.0 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Peripla_BP_5 PF13433.6 AIM20940.1 - 6.1e-172 571.6 0.0 7e-172 571.4 0.0 1.0 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_6 PF13458.6 AIM20940.1 - 7.8e-75 252.7 1.9 1e-74 252.3 1.9 1.1 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 AIM20940.1 - 0.0012 18.0 0.0 0.0085 15.2 0.0 1.9 2 0 0 2 2 2 1 Receptor family ligand binding region TAT_signal PF10518.9 AIM20940.1 - 0.022 14.6 3.3 0.07 13.0 3.3 1.9 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Pex14_N PF04695.13 AIM20940.1 - 0.13 13.0 0.0 0.31 11.7 0.0 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CdiI_N PF18228.1 AIM20940.1 - 0.17 11.7 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 CdiI N-terminal domain BPD_transp_2 PF02653.16 AIM20941.1 - 9.1e-51 172.6 38.5 1.1e-50 172.3 38.5 1.1 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component HEAT_2 PF13646.6 AIM20941.1 - 1.4e-11 44.6 12.4 7.2e-07 29.5 2.2 2.6 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.22 AIM20941.1 - 0.00035 20.6 9.3 1.1 9.7 0.1 4.7 3 1 1 4 4 4 2 HEAT repeat BPD_transp_2 PF02653.16 AIM20942.1 - 8.3e-41 139.9 33.4 8.3e-41 139.9 33.4 1.4 1 1 0 1 1 1 1 Branched-chain amino acid transport system / permease component ABC_tran PF00005.27 AIM20943.1 - 6e-29 101.3 0.0 9e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter BCA_ABC_TP_C PF12399.8 AIM20943.1 - 9.3e-09 35.0 0.2 1.5e-08 34.3 0.2 1.4 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_21 PF13304.6 AIM20943.1 - 8.9e-08 32.3 0.2 0.00062 19.7 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIM20943.1 - 1.5e-06 27.9 0.0 1.6e-05 24.4 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AIM20943.1 - 0.0001 22.9 0.1 0.00021 21.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 AIM20943.1 - 0.00071 19.4 0.0 0.0015 18.3 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AIM20943.1 - 0.00076 19.8 0.7 0.024 14.9 0.7 2.2 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AIM20943.1 - 0.0016 18.2 0.0 0.0028 17.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 AIM20943.1 - 0.0016 18.2 0.0 0.0044 16.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AIM20943.1 - 0.0028 18.1 0.1 0.0045 17.4 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 AIM20943.1 - 0.016 14.9 0.0 0.1 12.3 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_27 PF13514.6 AIM20943.1 - 0.022 14.4 0.0 0.053 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 AIM20943.1 - 0.086 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase ATP-synt_ab PF00006.25 AIM20943.1 - 0.094 12.4 0.0 0.68 9.5 0.0 2.0 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.29 AIM20943.1 - 0.11 12.9 0.1 0.34 11.3 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_13 PF13166.6 AIM20943.1 - 0.11 11.1 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 AIM20943.1 - 0.17 11.8 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 AIM20944.1 - 2e-30 106.1 0.0 2.5e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIM20944.1 - 5.2e-11 42.9 0.0 1.1e-05 25.4 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AIM20944.1 - 0.002 18.5 0.0 0.0026 18.2 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 AIM20944.1 - 0.0025 18.3 0.0 0.0035 17.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 AIM20944.1 - 0.0029 17.4 0.0 0.0039 17.0 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AIM20944.1 - 0.0037 17.2 0.0 0.0058 16.6 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 AIM20944.1 - 0.0069 16.1 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.12 AIM20944.1 - 0.022 14.6 0.1 0.04 13.8 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 AIM20944.1 - 0.083 13.2 0.5 0.33 11.2 0.5 2.0 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 AIM20944.1 - 0.089 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase ParE_toxin PF05016.15 AIM20945.1 - 9.5e-11 42.2 0.4 1e-10 42.1 0.4 1.0 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE ParD_antitoxin PF03693.14 AIM20946.1 - 1.1e-16 61.0 0.2 1.3e-16 60.8 0.2 1.0 1 0 0 1 1 1 1 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH Abhydrolase_8 PF06259.12 AIM20946.1 - 0.11 12.1 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase RHH_1 PF01402.21 AIM20946.1 - 0.12 12.4 3.0 0.39 10.7 0.1 2.4 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family DUF2165 PF09933.9 AIM20947.1 - 9.6e-28 97.2 8.9 1.1e-27 97.1 8.9 1.1 1 0 0 1 1 1 1 Predicted small integral membrane protein (DUF2165) Acetyltransf_1 PF00583.25 AIM20948.1 - 2.4e-15 56.8 0.1 3.6e-15 56.2 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AIM20948.1 - 4.6e-09 36.3 0.0 6.3e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AIM20948.1 - 9.8e-09 35.5 0.1 1.7e-08 34.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AIM20948.1 - 4.5e-07 29.7 0.0 6.6e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 AIM20948.1 - 0.00015 21.9 0.0 0.00018 21.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AIM20948.1 - 0.00058 20.5 0.0 0.00072 20.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ParE_toxin PF05016.15 AIM20949.1 - 9.8e-09 35.7 0.0 1.2e-08 35.5 0.0 1.1 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE PhdYeFM_antitox PF02604.19 AIM20950.1 - 2.9e-15 55.8 0.2 3.3e-15 55.6 0.2 1.1 1 0 0 1 1 1 1 Antitoxin Phd_YefM, type II toxin-antitoxin system FAD_binding_3 PF01494.19 AIM20951.1 - 1.3e-44 152.9 0.0 2.3e-44 152.1 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 AIM20951.1 - 0.079 13.2 0.0 0.69 10.2 0.0 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain SE PF08491.10 AIM20951.1 - 0.084 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase LysR_substrate PF03466.20 AIM20952.1 - 6.5e-28 97.5 5.7 9e-28 97.1 5.7 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM20952.1 - 2.1e-18 66.0 0.4 5.8e-18 64.6 0.4 1.8 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_11 PF08279.12 AIM20952.1 - 0.00078 19.3 0.0 0.0017 18.3 0.0 1.6 1 0 0 1 1 1 1 HTH domain HTH_24 PF13412.6 AIM20952.1 - 0.0017 17.8 0.0 0.0037 16.8 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 AIM20952.1 - 0.014 15.4 0.0 0.034 14.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_5 PF01022.20 AIM20952.1 - 0.016 15.0 0.1 0.032 14.1 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 AIM20952.1 - 0.068 13.1 0.4 0.23 11.4 0.0 2.1 2 0 0 2 2 2 0 MarR family HTH_30 PF13556.6 AIM20952.1 - 0.095 12.5 0.0 0.3 10.9 0.0 1.9 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain MarR PF01047.22 AIM20952.1 - 0.13 12.3 0.1 0.4 10.6 0.1 1.8 2 0 0 2 2 2 0 MarR family Rhodanese PF00581.20 AIM20953.1 - 3.1e-34 117.7 0.0 2.6e-18 66.5 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain NUDIX PF00293.28 AIM20954.1 - 6.4e-15 55.4 0.1 8.9e-15 54.9 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 AIM20954.1 - 0.013 15.5 0.2 0.019 14.9 0.2 1.5 1 1 0 1 1 1 0 NUDIX domain NAD_binding_10 PF13460.6 AIM20955.1 - 0.00028 20.8 0.0 0.00038 20.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 AIM20955.1 - 0.0014 19.1 0.0 0.0021 18.5 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 AIM20955.1 - 0.0023 17.4 0.0 0.0032 17.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 AIM20955.1 - 0.043 14.1 0.0 0.064 13.5 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Arabinose_bd PF12625.7 AIM20956.1 - 3.8e-39 134.7 4.9 3.8e-39 134.7 4.9 1.7 2 0 0 2 2 2 1 Arabinose-binding domain of AraC transcription regulator, N-term HTH_18 PF12833.7 AIM20956.1 - 8.3e-19 67.6 0.5 2.1e-18 66.3 0.5 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AIM20956.1 - 7.2e-07 29.2 0.0 0.0016 18.5 0.0 2.7 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_30 PF13556.6 AIM20956.1 - 0.007 16.1 0.6 0.02 14.7 0.6 1.7 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_8 PF02954.19 AIM20956.1 - 0.017 14.9 0.1 0.19 11.6 0.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family HTH_Tnp_ISL3 PF13542.6 AIM20956.1 - 0.024 14.1 0.0 0.075 12.5 0.0 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 DUF4250 PF14056.6 AIM20956.1 - 0.058 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) Aminotran_1_2 PF00155.21 AIM20957.1 - 1.1e-37 130.1 0.0 1.3e-37 129.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II GntR PF00392.21 AIM20957.1 - 7.2e-15 54.4 0.4 2.2e-14 52.8 0.4 1.9 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_41 PF14502.6 AIM20957.1 - 0.00038 20.1 0.0 0.00094 18.8 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 AIM20957.1 - 0.013 15.4 0.2 0.045 13.6 0.2 1.9 1 0 0 1 1 1 0 MarR family Aminotran_MocR PF12897.7 AIM20957.1 - 0.039 12.7 0.0 0.17 10.6 0.0 1.9 1 1 0 1 1 1 0 Alanine-glyoxylate amino-transferase DUF1127 PF06568.11 AIM20958.1 - 2.1e-10 40.1 12.8 2.1e-10 40.1 12.8 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1127) GST_N_3 PF13417.6 AIM20959.1 - 2.9e-14 53.2 0.0 5e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 AIM20959.1 - 1.7e-12 47.5 0.0 2.7e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AIM20959.1 - 2.8e-12 46.8 0.0 4.7e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 AIM20959.1 - 1.7e-06 28.0 1.3 3e-06 27.2 1.3 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 AIM20959.1 - 2.6e-05 24.4 0.0 3.8e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 AIM20959.1 - 0.0018 18.4 0.0 0.0026 17.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GFO_IDH_MocA PF01408.22 AIM20960.1 - 8.6e-24 84.7 0.1 2.8e-23 83.0 0.1 1.8 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 AIM20960.1 - 1.8e-09 37.6 0.0 3.3e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 AIM20960.1 - 3.2e-07 31.0 0.1 5.8e-07 30.2 0.1 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Peripla_BP_6 PF13458.6 AIM20960.1 - 0.002 17.8 0.0 0.0032 17.2 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein Amidohydro_3 PF07969.11 AIM20961.1 - 2.6e-123 413.0 0.4 3.1e-123 412.7 0.4 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 AIM20961.1 - 4e-07 29.7 0.0 9.1e-06 25.2 0.0 2.4 3 0 0 3 3 3 1 Amidohydrolase family ABM PF03992.16 AIM20962.1 - 6.7e-07 29.3 0.0 1e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Isochorismatase PF00857.20 AIM20963.1 - 1.3e-18 67.8 0.1 3.2e-18 66.5 0.1 1.6 1 1 0 1 1 1 1 Isochorismatase family LysR_substrate PF03466.20 AIM20964.1 - 3.4e-23 82.1 0.9 4.7e-23 81.7 0.9 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM20964.1 - 7.3e-16 57.9 0.1 1.4e-15 56.9 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 AIM20964.1 - 0.038 13.9 0.1 0.09 12.7 0.1 1.6 1 0 0 1 1 1 0 MarR family TolA PF06519.11 AIM20965.1 - 6.6e-13 48.7 0.0 7.7e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 TolA C-terminal TonB_C PF03544.14 AIM20965.1 - 7.4e-05 23.1 0.0 0.00013 22.3 0.0 1.4 1 0 0 1 1 1 1 Gram-negative bacterial TonB protein C-terminal TonB_2 PF13103.6 AIM20965.1 - 7.8e-05 22.8 0.1 0.00014 22.0 0.0 1.4 2 0 0 2 2 2 1 TonB C terminal LPAM_1 PF08139.12 AIM20965.1 - 0.38 11.3 4.5 1.3 9.7 4.5 1.9 1 1 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site FA_desaturase PF00487.24 AIM20966.1 - 1.1e-32 113.9 24.4 1.1e-32 113.9 24.4 2.1 1 1 1 2 2 2 2 Fatty acid desaturase OpuAC PF04069.12 AIM20967.1 - 1.8e-56 191.6 5.0 2.1e-56 191.4 5.0 1.0 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system BPD_transp_1 PF00528.22 AIM20968.1 - 1.1e-17 64.4 21.6 1.1e-17 64.4 21.6 3.0 2 1 1 3 3 3 2 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 AIM20969.1 - 2.1e-31 109.3 0.0 3.1e-31 108.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIM20969.1 - 2.8e-07 30.6 2.1 0.0069 16.2 0.1 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system CBS PF00571.28 AIM20969.1 - 2.1e-05 24.9 0.0 7.8e-05 23.0 0.0 2.0 1 0 0 1 1 1 1 CBS domain AAA_30 PF13604.6 AIM20969.1 - 0.00018 21.3 0.0 0.00049 19.9 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_15 PF13175.6 AIM20969.1 - 0.00022 21.1 0.0 0.00029 20.7 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_16 PF13191.6 AIM20969.1 - 0.00028 21.3 0.8 0.00088 19.7 0.8 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AIM20969.1 - 0.00037 20.2 0.1 0.00072 19.2 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AIM20969.1 - 0.0011 19.3 0.0 0.0027 18.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AIM20969.1 - 0.0031 17.4 0.0 0.0053 16.7 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase Zeta_toxin PF06414.12 AIM20969.1 - 0.0034 16.7 0.0 0.12 11.7 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin G-alpha PF00503.20 AIM20969.1 - 0.0042 16.3 0.0 0.0047 16.1 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit SMC_N PF02463.19 AIM20969.1 - 0.0053 16.2 0.1 0.99 8.8 0.1 2.2 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 AIM20969.1 - 0.058 13.0 0.3 0.17 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 AIM20969.1 - 0.06 12.7 0.2 0.17 11.2 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF87 PF01935.17 AIM20969.1 - 0.13 12.3 0.1 0.23 11.5 0.1 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain BPD_transp_1 PF00528.22 AIM20970.1 - 5.3e-24 85.0 16.7 5.3e-24 85.0 16.7 1.5 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component DUF1189 PF06691.11 AIM20970.1 - 0.087 12.4 1.0 0.19 11.3 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) Ldr_toxin PF13940.6 AIM20970.1 - 3.4 7.8 7.8 0.19 11.8 0.6 2.8 3 0 0 3 3 3 0 Toxin Ldr, type I toxin-antitoxin system Phosphonate-bd PF12974.7 AIM20971.1 - 1.4e-18 67.4 0.0 1.7e-18 67.1 0.0 1.1 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 AIM20971.1 - 0.065 12.7 0.0 0.083 12.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 adh_short_C2 PF13561.6 AIM20972.1 - 1.2e-31 110.1 3.7 1.6e-31 109.7 3.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AIM20972.1 - 2.3e-20 72.9 0.6 2.8e-20 72.6 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 AIM20972.1 - 2.9e-06 26.9 0.3 6.8e-06 25.7 0.1 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 AIM20972.1 - 4e-05 23.6 1.5 9.5e-05 22.4 0.8 1.9 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 AIM20972.1 - 0.00034 20.6 2.8 0.00034 20.6 1.6 1.6 2 0 0 2 2 2 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 AIM20972.1 - 0.037 13.1 0.6 0.098 11.7 0.1 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain 2-Hacid_dh_C PF02826.19 AIM20972.1 - 0.062 12.6 0.0 0.17 11.2 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MarR PF01047.22 AIM20973.1 - 4.9e-06 26.4 0.2 7.3e-06 25.8 0.2 1.3 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 AIM20973.1 - 1.5e-05 25.0 0.3 2.1e-05 24.5 0.3 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.10 AIM20973.1 - 0.00014 21.6 0.9 0.00023 20.9 0.9 1.3 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 AIM20973.1 - 0.006 16.5 0.2 0.0096 15.8 0.2 1.3 1 0 0 1 1 1 1 MarR family TrmB PF01978.19 AIM20973.1 - 0.0095 15.8 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_27 PF13463.6 AIM20973.1 - 0.014 15.9 0.0 0.019 15.4 0.0 1.2 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_15 PF12324.8 AIM20973.1 - 0.028 14.4 0.1 0.053 13.5 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase HTH_29 PF13551.6 AIM20973.1 - 0.03 14.4 0.0 0.045 13.8 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix HTH_Crp_2 PF13545.6 AIM20973.1 - 0.033 14.2 0.2 0.058 13.4 0.2 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_5 PF01022.20 AIM20973.1 - 0.034 14.0 0.1 0.055 13.3 0.1 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family DUF1822 PF08852.11 AIM20973.1 - 0.053 12.5 0.1 0.059 12.4 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) HemN_C PF06969.16 AIM20973.1 - 0.055 13.5 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 HemN C-terminal domain Replic_Relax PF13814.6 AIM20973.1 - 0.073 13.1 0.1 0.1 12.6 0.1 1.2 1 0 0 1 1 1 0 Replication-relaxation HTH_34 PF13601.6 AIM20973.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain LysR_substrate PF03466.20 AIM20975.1 - 3.6e-42 144.1 7.7 5.2e-42 143.6 7.7 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM20975.1 - 4.8e-19 68.1 1.4 4.8e-19 68.1 1.4 2.1 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 AIM20975.1 - 0.095 12.6 4.4 0.1 12.5 0.2 3.1 4 0 0 4 4 4 0 MarR family EamA PF00892.20 AIM20977.1 - 3e-40 137.6 40.4 6.1e-22 78.3 15.3 2.0 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 AIM20977.1 - 0.0075 15.6 9.3 0.07 12.5 2.1 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family RseC_MucC PF04246.12 AIM20977.1 - 6.8 6.6 26.5 0.33 10.9 1.3 4.2 3 1 1 4 4 4 0 Positive regulator of sigma(E), RseC/MucC DUF2878 PF11086.8 AIM20978.1 - 2.5e-23 83.0 24.9 2.9e-23 82.8 24.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2878) PadR PF03551.14 AIM20979.1 - 0.0084 16.0 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family MFS_1 PF07690.16 AIM20980.1 - 1.6e-30 106.3 56.8 1.6e-30 106.3 56.8 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 AIM20980.1 - 1.1e-05 24.3 11.3 1.1e-05 24.3 11.3 3.0 1 1 1 2 2 2 1 MFS/sugar transport protein TRI12 PF06609.13 AIM20980.1 - 0.01 14.3 12.2 0.0052 15.3 10.0 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) TMEM208_SND2 PF05620.11 AIM20980.1 - 0.84 9.4 9.4 0.6 9.9 0.9 3.5 2 1 1 3 3 3 0 SRP-independent targeting protein 2/TMEM208 HTH_3 PF01381.22 AIM20981.1 - 3.5e-14 52.6 0.3 6e-14 51.8 0.3 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 AIM20981.1 - 7.5e-14 51.8 8.0 1.4e-13 51.0 8.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 AIM20981.1 - 1.5e-11 44.1 0.1 2.2e-11 43.6 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 AIM20981.1 - 3.1e-08 33.9 0.3 5.1e-08 33.2 0.3 1.4 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_37 PF13744.6 AIM20981.1 - 0.00014 21.8 0.2 0.00027 20.9 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Cupin_2 PF07883.11 AIM20981.1 - 0.00025 20.7 0.0 0.00036 20.2 0.0 1.2 1 0 0 1 1 1 1 Cupin domain HTH_IclR PF09339.10 AIM20981.1 - 0.0007 19.4 0.3 0.0018 18.0 0.3 1.7 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_25 PF13413.6 AIM20981.1 - 0.00081 19.2 1.1 0.00081 19.2 1.1 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 AIM20981.1 - 0.0014 18.7 0.0 0.0078 16.3 0.0 2.1 1 1 1 2 2 2 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_23 PF13384.6 AIM20981.1 - 0.01 15.6 0.5 0.022 14.5 0.5 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_11 PF08279.12 AIM20981.1 - 0.012 15.5 0.6 0.021 14.8 0.6 1.4 1 0 0 1 1 1 0 HTH domain MarR PF01047.22 AIM20981.1 - 0.019 14.9 0.0 0.064 13.2 0.0 1.9 2 0 0 2 2 2 0 MarR family TniQ PF06527.11 AIM20981.1 - 0.022 15.5 1.1 3 8.6 0.0 2.2 1 1 1 2 2 2 0 TniQ RHH_4 PF13467.6 AIM20981.1 - 0.03 14.2 0.2 2 8.4 0.0 2.3 1 1 1 2 2 2 0 Ribbon-helix-helix domain Sigma70_r4 PF04545.16 AIM20981.1 - 0.032 13.8 0.3 0.061 12.9 0.3 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_Crp_2 PF13545.6 AIM20981.1 - 0.057 13.4 3.0 0.057 13.4 3.0 1.9 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_24 PF13412.6 AIM20981.1 - 0.082 12.5 0.1 0.27 10.8 0.1 1.9 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DprA_WH PF17782.1 AIM20981.1 - 0.11 12.6 6.1 0.56 10.4 0.5 3.2 3 0 0 3 3 3 0 DprA winged helix domain HTH_35 PF13693.6 AIM20981.1 - 0.14 12.2 0.3 0.28 11.2 0.3 1.6 1 1 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_32 PF13565.6 AIM20981.1 - 0.14 12.8 2.3 0.19 12.4 0.9 1.8 2 0 0 2 2 2 0 Homeodomain-like domain Acetyltransf_10 PF13673.7 AIM20982.1 - 7.9e-14 51.7 0.0 1.1e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AIM20982.1 - 1.2e-12 48.1 0.0 1.5e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AIM20982.1 - 6.4e-12 45.7 0.0 1.1e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AIM20982.1 - 6.9e-07 29.4 0.1 1.4e-06 28.4 0.1 1.5 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AIM20982.1 - 1.6e-06 28.0 0.1 3.2e-06 27.0 0.1 1.5 1 0 0 1 1 1 1 FR47-like protein PanZ PF12568.8 AIM20982.1 - 8.8e-05 22.2 0.4 0.00012 21.8 0.4 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_3 PF13302.7 AIM20982.1 - 0.014 16.1 0.0 0.018 15.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AIM20982.1 - 0.025 14.7 0.0 0.039 14.1 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 AIM20982.1 - 0.15 12.1 0.1 0.26 11.3 0.1 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acid_phosphat_B PF03767.14 AIM20983.1 - 1.5e-55 188.3 0.4 1.8e-55 188.1 0.4 1.1 1 0 0 1 1 1 1 HAD superfamily, subfamily IIIB (Acid phosphatase) Hydrolase_6 PF13344.6 AIM20983.1 - 0.0017 18.4 0.1 0.0051 16.9 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Ribosomal_S11 PF00411.19 AIM20983.1 - 0.061 13.7 0.1 0.15 12.5 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein S11 Acetyltransf_1 PF00583.25 AIM20984.1 - 1.9e-19 70.0 0.1 3.8e-13 49.7 0.1 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AIM20984.1 - 1.5e-18 66.9 0.0 9.2e-11 41.8 0.1 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AIM20984.1 - 1.7e-15 57.2 0.0 1.4e-06 28.6 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 AIM20984.1 - 6.8e-11 42.0 0.1 3.1e-07 30.3 0.1 2.3 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_CG PF14542.6 AIM20984.1 - 7.2e-10 38.9 0.1 4.1e-05 23.6 0.1 2.4 2 0 0 2 2 2 2 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 AIM20984.1 - 9.3e-08 32.2 0.1 0.0025 17.9 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 AIM20984.1 - 4.1e-06 27.0 1.2 7.8e-06 26.1 0.1 2.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 AIM20984.1 - 0.00054 19.7 0.5 0.0083 15.8 0.2 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 AIM20984.1 - 0.0058 16.6 0.0 0.36 10.8 0.0 2.7 3 0 0 3 3 3 1 ESCO1/2 acetyl-transferase PanZ PF12568.8 AIM20984.1 - 0.014 15.2 0.1 0.029 14.1 0.1 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_3 PF13302.7 AIM20984.1 - 0.034 14.8 0.1 0.27 11.9 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Porin_1 PF00267.21 AIM20985.1 - 5.8e-137 456.7 26.2 6.6e-137 456.5 26.2 1.0 1 0 0 1 1 1 1 Gram-negative porin BBP2_2 PF10082.9 AIM20985.1 - 0.001 18.0 1.4 0.0012 17.8 0.2 1.8 2 0 0 2 2 2 1 Putative beta-barrel porin 2 GST_N_3 PF13417.6 AIM20986.1 - 2.5e-09 37.4 0.0 4.1e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AIM20986.1 - 1.2e-07 31.9 0.0 2.4e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 AIM20986.1 - 5e-07 30.0 0.0 9.6e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 AIM20986.1 - 3e-05 24.1 0.0 4.6e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain AAA_25 PF13481.6 AIM20986.1 - 0.0046 16.5 0.1 0.016 14.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain MCD_N PF17408.2 AIM20986.1 - 0.031 14.4 0.0 0.058 13.5 0.0 1.4 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase N-terminal domain GST_C_2 PF13410.6 AIM20986.1 - 0.041 13.9 0.6 0.098 12.7 0.1 2.0 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain CMD PF02627.20 AIM20987.1 - 2e-20 72.6 0.2 2.4e-20 72.4 0.2 1.1 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Tautomerase_2 PF14552.6 AIM20988.1 - 3.8e-27 94.2 0.0 5e-26 90.6 0.0 1.9 1 1 1 2 2 2 2 Tautomerase enzyme Tautomerase PF01361.21 AIM20988.1 - 9.2e-15 54.3 0.0 3.5e-06 26.8 0.0 2.1 2 0 0 2 2 2 2 Tautomerase enzyme Helicase_C_2 PF13307.6 AIM20989.1 - 1.1e-25 90.8 0.0 2.3e-25 89.8 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 AIM20989.1 - 8.6e-08 32.0 0.0 1.6e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 DEAD PF00270.29 AIM20989.1 - 2.9e-06 27.2 0.2 0.0025 17.6 0.0 3.6 4 0 0 4 4 4 1 DEAD/DEAH box helicase ResIII PF04851.15 AIM20989.1 - 7.2e-06 26.1 0.0 0.011 15.8 0.0 2.3 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit GAPES3 PF17154.4 AIM20989.1 - 0.029 14.4 0.0 0.086 12.8 0.0 1.8 1 0 0 1 1 1 0 Gammaproteobacterial periplasmic sensor domain Med22 PF06179.12 AIM20989.1 - 0.038 14.2 0.1 0.24 11.6 0.0 2.3 2 0 0 2 2 2 0 Surfeit locus protein 5 subunit 22 of Mediator complex OSTbeta PF15048.6 AIM20989.1 - 0.061 13.5 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein DUF3287 PF11690.8 AIM20989.1 - 0.089 12.5 0.1 0.22 11.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) AAA_16 PF13191.6 AIM20989.1 - 0.092 13.1 0.1 2.4 8.5 0.1 2.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 AIM20989.1 - 0.17 12.2 0.3 13 6.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain AsnC_trans_reg PF01037.21 AIM20990.1 - 7.7e-16 57.8 0.1 1.4e-15 57.0 0.1 1.4 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 AIM20990.1 - 2.6e-15 55.7 1.2 3e-15 55.5 0.3 1.6 2 0 0 2 2 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 AIM20990.1 - 1.3e-14 53.7 2.2 1.3e-14 53.7 2.2 1.7 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain MarR PF01047.22 AIM20990.1 - 1.6e-05 24.8 0.4 7.8e-05 22.5 0.1 2.0 2 0 0 2 2 2 1 MarR family HTH_20 PF12840.7 AIM20990.1 - 2.4e-05 24.3 1.2 0.00016 21.7 0.1 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_IclR PF09339.10 AIM20990.1 - 2.9e-05 23.8 1.5 7.3e-05 22.5 0.5 2.0 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_5 PF01022.20 AIM20990.1 - 3.6e-05 23.5 0.1 6.9e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_27 PF13463.6 AIM20990.1 - 0.0012 19.3 0.2 0.0071 16.8 0.0 2.2 2 1 0 2 2 2 1 Winged helix DNA-binding domain MarR_2 PF12802.7 AIM20990.1 - 0.0028 17.5 0.1 0.0045 16.8 0.1 1.4 1 0 0 1 1 1 1 MarR family Fe_dep_repress PF01325.19 AIM20990.1 - 0.0029 17.8 0.0 0.0061 16.7 0.0 1.6 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_10 PF04967.12 AIM20990.1 - 0.0033 17.2 0.2 0.0066 16.2 0.2 1.5 1 0 0 1 1 1 1 HTH DNA binding domain DUF294_C PF10335.9 AIM20990.1 - 0.011 15.5 0.1 0.023 14.5 0.0 1.6 2 0 0 2 2 2 0 Putative nucleotidyltransferase substrate binding domain HTH_Crp_2 PF13545.6 AIM20990.1 - 0.017 15.1 0.6 0.031 14.2 0.2 1.6 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain TrmB PF01978.19 AIM20990.1 - 0.024 14.5 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_34 PF13601.6 AIM20990.1 - 0.033 14.4 0.0 0.057 13.6 0.0 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain LexA_DNA_bind PF01726.16 AIM20990.1 - 0.045 13.5 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 LexA DNA binding domain BRICHOS PF04089.14 AIM20990.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 BRICHOS domain EamA PF00892.20 AIM20991.1 - 4.1e-31 108.0 40.0 1.6e-17 63.9 15.0 2.0 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 AIM20991.1 - 0.029 13.7 5.5 0.07 12.5 5.5 1.7 1 1 0 1 1 1 0 Triose-phosphate Transporter family TssN PF17555.2 AIM20991.1 - 3.1 7.1 5.0 0.49 9.7 0.5 1.8 2 0 0 2 2 2 0 Type VI secretion system, TssN CPP1-like PF11833.8 AIM20991.1 - 8.5 6.0 16.4 0.089 12.4 4.5 2.4 2 1 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Sigma54_activat PF00158.26 AIM20992.1 - 3.6e-62 209.0 0.0 5e-62 208.5 0.0 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain PrpR_N PF06506.11 AIM20992.1 - 1.2e-46 158.3 0.0 1.8e-46 157.7 0.0 1.3 1 0 0 1 1 1 1 Propionate catabolism activator Sigma54_activ_2 PF14532.6 AIM20992.1 - 8.4e-20 71.3 0.0 7.6e-19 68.2 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 AIM20992.1 - 1.6e-11 43.8 1.0 4.1e-11 42.5 1.0 1.8 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 AIM20992.1 - 7.9e-05 22.7 0.0 0.0082 16.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 AIM20992.1 - 0.0002 20.8 0.1 0.024 14.0 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA PF00004.29 AIM20992.1 - 0.00038 20.9 0.0 0.00065 20.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) HTH_30 PF13556.6 AIM20992.1 - 0.0013 18.5 0.0 0.0047 16.7 0.0 1.9 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_1 PF00126.27 AIM20992.1 - 0.002 18.0 0.0 0.0082 16.1 0.0 2.1 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_psq PF05225.16 AIM20992.1 - 0.0055 16.4 0.0 0.034 13.9 0.0 2.3 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_Tnp_ISL3 PF13542.6 AIM20992.1 - 0.012 15.0 0.0 0.037 13.4 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 AAA_3 PF07726.11 AIM20992.1 - 0.015 15.1 0.0 0.066 13.1 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) HTH_23 PF13384.6 AIM20992.1 - 0.018 14.9 0.0 0.055 13.3 0.0 1.9 1 0 0 1 1 1 0 Homeodomain-like domain HTH_24 PF13412.6 AIM20992.1 - 0.072 12.7 0.6 0.23 11.1 0.1 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding T2SSE PF00437.20 AIM20992.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein HTH_AsnC-type PF13404.6 AIM20992.1 - 0.21 11.4 3.8 0.22 11.4 0.2 2.8 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain MCM PF00493.23 AIM20992.1 - 0.23 10.6 0.0 0.68 9.0 0.0 1.7 2 0 0 2 2 2 0 MCM P-loop domain PEP_mutase PF13714.6 AIM20993.1 - 1.3e-50 172.1 4.3 1.5e-50 171.9 4.3 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 AIM20993.1 - 2.1e-11 43.0 0.3 3.1e-11 42.5 0.3 1.2 1 0 0 1 1 1 1 Isocitrate lyase family EccE PF11203.8 AIM20993.1 - 0.13 12.6 0.8 0.91 9.9 0.0 2.4 2 1 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE Citrate_synt PF00285.21 AIM20994.1 - 1.1e-112 376.7 0.0 1.3e-112 376.4 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain MmgE_PrpD PF03972.14 AIM20995.1 - 3.6e-157 523.4 1.9 4.2e-157 523.2 1.9 1.0 1 0 0 1 1 1 1 MmgE/PrpD family KORA PF16509.5 AIM20995.1 - 0.049 13.9 0.1 0.13 12.6 0.1 1.7 1 0 0 1 1 1 0 TrfB plasmid transcriptional repressor LysE PF01810.18 AIM20996.1 - 1.1e-30 106.6 11.4 1.2e-30 106.4 11.4 1.0 1 0 0 1 1 1 1 LysE type translocator TerC PF03741.16 AIM20996.1 - 0.071 12.8 4.3 0.071 12.8 0.6 2.2 2 0 0 2 2 2 0 Integral membrane protein TerC family MLTR_LBD PF17765.1 AIM20997.1 - 2.5e-43 148.1 6.1 3.4e-43 147.7 6.1 1.2 1 0 0 1 1 1 1 MmyB-like transcription regulator ligand binding domain HTH_31 PF13560.6 AIM20997.1 - 6.6e-16 58.4 3.5 1.7e-15 57.1 3.5 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 AIM20997.1 - 0.035 14.1 0.0 0.082 13.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix MFS_1 PF07690.16 AIM20998.1 - 1.1e-41 143.0 111.7 1.8e-37 129.1 71.4 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 AIM20998.1 - 0.0053 15.1 0.2 0.0053 15.1 0.2 3.0 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family DUF2374 PF09574.10 AIM20998.1 - 7.3 6.5 8.4 5.7 6.8 1.2 3.1 2 0 0 2 2 2 0 Protein of unknown function (Duf2374) FMN_bind_2 PF04299.12 AIM20999.1 - 4.1e-59 199.1 0.0 4.9e-59 198.8 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain Glycos_trans_3N PF02885.17 AIM21000.1 - 2.2e-10 40.2 0.3 5.5e-10 39.0 0.3 1.7 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Glycos_transf_3 PF00591.21 AIM21000.1 - 1e-08 35.1 0.0 1.4e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Peptidase_M3 PF01432.20 AIM21001.1 - 3.4e-22 79.3 0.0 3.7e-21 75.9 0.0 2.0 1 1 0 1 1 1 1 Peptidase family M3 Hemerythrin PF01814.23 AIM21001.1 - 0.47 11.1 4.5 0.72 10.5 0.2 3.0 3 0 0 3 3 3 0 Hemerythrin HHE cation binding domain Pro_CA PF00484.19 AIM21002.1 - 1e-47 162.3 0.1 1.2e-47 162.1 0.1 1.0 1 0 0 1 1 1 1 Carbonic anhydrase DUF1471 PF07338.13 AIM21003.1 - 1e-16 60.6 1.0 1e-16 60.6 1.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1471) POR_N PF01855.19 AIM21003.1 - 0.021 14.6 1.9 0.024 14.4 1.7 1.4 1 1 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg PE PF00934.20 AIM21003.1 - 0.086 13.2 13.9 0.5 10.7 5.2 2.1 1 1 1 2 2 2 0 PE family Flavin_Reduct PF01613.18 AIM21004.1 - 1.2e-16 61.2 0.0 1.5e-16 60.8 0.0 1.0 1 0 0 1 1 1 1 Flavin reductase like domain Methyltransf_10 PF05971.12 AIM21005.1 - 4.2e-128 426.9 0.0 4.8e-128 426.7 0.0 1.0 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 AIM21005.1 - 0.0013 18.3 0.0 0.003 17.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain MCPsignal PF00015.21 AIM21006.1 - 2.2e-33 115.5 18.0 2.2e-33 115.5 18.0 2.3 2 1 1 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain PAS_3 PF08447.12 AIM21006.1 - 2.6e-28 98.2 0.0 4e-13 49.5 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 AIM21006.1 - 4e-28 97.8 0.1 5.3e-15 55.6 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 AIM21006.1 - 8.9e-25 87.0 0.0 2.8e-11 43.6 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 AIM21006.1 - 5.1e-18 65.1 0.0 6.1e-08 32.7 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 AIM21006.1 - 4.6e-05 23.3 0.1 0.17 12.0 0.0 3.1 2 1 1 3 3 3 2 PAS domain Staphopain_pro PF14731.6 AIM21006.1 - 0.0003 20.8 0.0 0.59 10.1 0.0 2.3 2 0 0 2 2 2 2 Staphopain proregion Cache_3-Cache_2 PF17201.4 AIM21006.1 - 0.00031 20.1 1.1 0.27 10.5 0.2 2.6 2 1 0 2 2 2 2 Cache 3/Cache 2 fusion domain sCache_3_3 PF17202.4 AIM21006.1 - 0.00033 21.0 0.0 0.73 10.3 0.0 2.6 2 0 0 2 2 2 2 Single cache domain 3 IclR PF01614.18 AIM21006.1 - 0.003 17.4 1.4 2 8.3 0.0 2.9 3 0 0 3 3 3 2 Bacterial transcriptional regulator BORCS7 PF16088.5 AIM21006.1 - 0.036 14.3 2.3 0.46 10.8 0.5 2.8 2 1 0 2 2 2 0 BLOC-1-related complex sub-unit 7 LisH_TPL PF17814.1 AIM21006.1 - 0.054 13.2 0.1 7.6 6.3 0.0 2.8 2 0 0 2 2 2 0 LisH-like dimerisation domain GBP_repeat PF02526.14 AIM21006.1 - 0.096 12.4 0.8 2.3 8.0 0.0 2.5 2 0 0 2 2 2 0 Glycophorin-binding protein MF_alpha PF04648.12 AIM21006.1 - 0.18 12.2 1.5 5.8 7.4 0.0 2.9 2 0 0 2 2 2 0 Yeast mating factor alpha hormone DUF4200 PF13863.6 AIM21006.1 - 0.91 9.9 3.8 1.7 9.0 0.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) T7SS_ESX_EspC PF10824.8 AIM21006.1 - 0.91 10.0 10.2 1.4 9.4 1.5 2.9 1 1 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm DUF948 PF06103.11 AIM21006.1 - 4.8 7.5 13.2 3.9 7.8 2.1 4.0 3 2 0 3 3 3 0 Bacterial protein of unknown function (DUF948) TetR_N PF00440.23 AIM21007.1 - 1.5e-18 66.3 0.1 3.6e-18 65.1 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_7 PF14246.6 AIM21007.1 - 2.1e-08 34.2 0.6 3.6e-08 33.5 0.6 1.3 1 0 0 1 1 1 1 AefR-like transcriptional repressor, C-terminal domain TetR_C_11 PF16859.5 AIM21007.1 - 2.9e-07 30.8 0.7 5.3e-07 29.9 0.7 1.5 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_6 PF13977.6 AIM21007.1 - 9.7e-07 29.0 0.5 2.2e-06 27.9 0.5 1.6 1 0 0 1 1 1 1 BetI-type transcriptional repressor, C-terminal TetR_C_21 PF17926.1 AIM21007.1 - 0.00077 19.6 0.1 0.0015 18.6 0.1 1.5 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_36 PF18598.1 AIM21007.1 - 0.0013 18.6 0.2 0.0044 17.0 0.2 1.9 1 1 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_31 PF17940.1 AIM21007.1 - 0.014 15.6 1.1 0.023 14.9 1.1 1.6 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain eIF3_N PF09440.10 AIM21007.1 - 0.05 14.0 0.0 0.081 13.4 0.0 1.3 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain TetR_C_26 PF17934.1 AIM21007.1 - 0.059 13.7 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain LacI PF00356.21 AIM21007.1 - 0.075 12.8 0.2 0.21 11.4 0.2 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family Acetyltransf_1 PF00583.25 AIM21008.1 - 3.3e-15 56.3 0.0 6.4e-15 55.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AIM21008.1 - 8.3e-11 42.2 0.2 2e-10 40.9 0.2 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AIM21008.1 - 9.7e-11 41.7 0.1 1.9e-10 40.8 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AIM21008.1 - 1.1e-07 31.7 0.1 2e-07 30.9 0.1 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 AIM21008.1 - 6.6e-05 23.6 0.6 0.00021 22.0 0.6 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 AIM21008.1 - 0.00068 19.3 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AIM21008.1 - 0.0042 17.2 0.5 2 8.5 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AIM21008.1 - 0.0049 17.0 0.0 0.0098 16.0 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 AIM21008.1 - 0.0054 16.9 0.0 0.036 14.2 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 AIM21008.1 - 0.093 12.5 1.3 0.099 12.4 0.2 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain, PanZ Peptidase_S15 PF02129.18 AIM21009.1 - 7.8e-11 42.1 1.2 1e-10 41.7 1.2 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 AIM21009.1 - 5.7e-10 38.9 0.2 9.3e-10 38.2 0.2 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 AIM21009.1 - 1.7e-05 24.4 0.7 0.00011 21.8 0.7 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 AIM21009.1 - 0.02 14.6 0.4 0.029 14.0 0.4 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold PH_5 PF15405.6 AIM21009.1 - 0.043 13.9 0.0 0.072 13.2 0.0 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain MS_channel PF00924.18 AIM21010.1 - 5.9e-38 130.5 2.5 1.5e-37 129.1 2.5 1.8 1 0 0 1 1 1 1 Mechanosensitive ion channel ABC_tran PF00005.27 AIM21011.1 - 1.9e-36 125.6 0.0 2.6e-36 125.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIM21011.1 - 1.5e-12 48.0 0.0 9.2e-06 25.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIM21011.1 - 6.2e-09 35.6 0.2 2e-06 27.4 0.2 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AIM21011.1 - 1.1e-05 26.1 0.1 1.7e-05 25.4 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AIM21011.1 - 1.2e-05 25.7 0.2 3.1e-05 24.4 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AIM21011.1 - 1.8e-05 24.4 0.0 3.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 AIM21011.1 - 3.6e-05 23.6 0.0 0.0047 16.7 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 AIM21011.1 - 5e-05 23.6 0.1 0.00033 20.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 AIM21011.1 - 0.00011 21.2 0.1 0.11 11.3 0.0 2.5 2 1 0 2 2 2 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 AIM21011.1 - 0.00022 21.2 0.1 0.00042 20.3 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_13 PF13166.6 AIM21011.1 - 0.00024 19.9 0.0 0.3 9.7 0.0 2.0 1 1 1 2 2 2 2 AAA domain TniB PF05621.11 AIM21011.1 - 0.00026 20.5 0.1 0.048 13.1 0.0 2.2 2 0 0 2 2 2 1 Bacterial TniB protein AAA_30 PF13604.6 AIM21011.1 - 0.0019 18.0 0.1 0.0038 17.0 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AIM21011.1 - 0.0027 17.9 0.1 0.0066 16.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain CobU PF02283.16 AIM21011.1 - 0.0028 17.2 0.1 0.046 13.3 0.0 2.2 2 0 0 2 2 2 1 Cobinamide kinase / cobinamide phosphate guanyltransferase IstB_IS21 PF01695.17 AIM21011.1 - 0.0029 17.3 0.0 0.11 12.3 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_18 PF13238.6 AIM21011.1 - 0.0037 17.8 0.0 0.0073 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 AIM21011.1 - 0.0042 17.0 0.1 0.0056 16.6 0.1 1.6 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea cobW PF02492.19 AIM21011.1 - 0.0048 16.5 0.1 0.02 14.5 0.0 1.9 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 AIM21011.1 - 0.0048 16.5 0.1 0.037 13.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 AIM21011.1 - 0.0077 15.5 0.1 0.02 14.1 0.1 1.8 1 1 0 1 1 1 1 NB-ARC domain Rad17 PF03215.15 AIM21011.1 - 0.013 15.4 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain NACHT PF05729.12 AIM21011.1 - 0.016 15.2 0.0 0.037 14.0 0.0 1.7 1 0 0 1 1 1 0 NACHT domain PhoH PF02562.16 AIM21011.1 - 0.03 13.8 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein RNA12 PF10443.9 AIM21011.1 - 0.032 13.0 0.0 0.054 12.2 0.0 1.3 1 0 0 1 1 1 0 RNA12 protein AAA_28 PF13521.6 AIM21011.1 - 0.036 14.3 0.3 0.1 12.8 0.1 1.9 2 1 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 AIM21011.1 - 0.038 14.2 0.2 0.59 10.4 0.2 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 AIM21011.1 - 0.046 13.4 0.3 0.083 12.6 0.0 1.6 2 0 0 2 2 1 0 AAA domain NTPase_1 PF03266.15 AIM21011.1 - 0.051 13.5 0.1 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 NTPase AAA_27 PF13514.6 AIM21011.1 - 0.057 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 AIM21011.1 - 0.071 12.5 0.0 0.24 10.7 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 AIM21011.1 - 0.077 12.7 0.0 0.2 11.3 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain T2SSE PF00437.20 AIM21011.1 - 0.081 12.0 0.1 0.15 11.1 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.6 AIM21011.1 - 0.09 12.8 0.0 0.29 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 AIM21011.1 - 0.098 13.0 0.1 0.26 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 AIM21011.1 - 0.11 12.6 0.1 0.24 11.5 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase CPT PF07931.12 AIM21011.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein SET PF00856.28 AIM21011.1 - 0.11 12.9 0.0 0.16 12.3 0.0 1.2 1 0 0 1 1 1 0 SET domain Adeno_IVa2 PF02456.15 AIM21011.1 - 0.15 10.9 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein BPD_transp_1 PF00528.22 AIM21012.1 - 8.5e-24 84.3 16.3 1.2e-23 83.9 16.3 1.2 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component MgtE PF01769.16 AIM21012.1 - 1.3 9.4 11.9 1.4 9.3 6.8 2.2 2 0 0 2 2 2 0 Divalent cation transporter SBP_bac_3 PF00497.20 AIM21013.1 - 1.5e-69 233.9 1.3 1.7e-69 233.7 1.3 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 AIM21013.1 - 2.9e-12 46.8 0.1 1.5e-10 41.3 0.1 2.3 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Phosphonate-bd PF12974.7 AIM21013.1 - 0.0087 15.7 0.1 0.055 13.1 0.1 2.2 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 AIM21013.1 - 0.022 14.7 0.5 0.072 13.0 0.4 1.8 1 1 0 1 1 1 0 NMT1/THI5 like zf-dskA_traR PF01258.17 AIM21014.1 - 3.1e-13 49.4 6.2 4.6e-13 48.9 6.2 1.2 1 0 0 1 1 1 1 Prokaryotic dksA/traR C4-type zinc finger DZR PF12773.7 AIM21014.1 - 1.9e-05 24.6 1.3 2.9e-05 24.0 1.3 1.2 1 0 0 1 1 1 1 Double zinc ribbon Auto_anti-p27 PF06677.12 AIM21014.1 - 0.0064 16.6 1.0 0.01 16.0 1.0 1.3 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zinc_ribbon_2 PF13240.6 AIM21014.1 - 0.011 15.4 1.2 0.25 11.1 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS91 PF14319.6 AIM21014.1 - 0.019 15.0 0.3 0.028 14.5 0.3 1.2 1 0 0 1 1 1 0 Transposase zinc-binding domain C1_1 PF00130.22 AIM21014.1 - 0.033 14.1 0.6 0.052 13.4 0.6 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Nudix_N_2 PF14803.6 AIM21014.1 - 0.083 12.8 2.9 0.31 11.0 0.2 2.3 2 0 0 2 2 2 0 Nudix N-terminal A2L_zn_ribbon PF08792.10 AIM21014.1 - 0.4 10.4 3.4 7.9 6.3 0.8 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain Ferritin PF00210.24 AIM21015.1 - 2.8e-24 85.7 0.2 3.2e-24 85.5 0.2 1.1 1 0 0 1 1 1 1 Ferritin-like domain T7SS_ESX_EspC PF10824.8 AIM21015.1 - 0.025 15.0 0.2 0.069 13.6 0.1 1.8 2 0 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm DUF1978 PF09321.10 AIM21015.1 - 0.093 12.0 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) DUF386 PF04074.12 AIM21017.1 - 1.6e-31 109.2 0.0 1.8e-31 109.1 0.0 1.0 1 0 0 1 1 1 1 YhcH/YjgK/YiaL EamA PF00892.20 AIM21018.1 - 1.5e-22 80.3 36.7 2.9e-18 66.4 12.1 2.3 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 AIM21018.1 - 0.12 11.6 0.1 0.18 10.9 0.1 1.2 1 0 0 1 1 1 0 Nucleotide-sugar transporter Ail_Lom PF06316.11 AIM21019.1 - 3.3e-25 89.0 4.4 3.4e-23 82.4 4.4 2.3 1 1 0 1 1 1 1 Enterobacterial Ail/Lom protein OMP_b-brl PF13505.6 AIM21019.1 - 5.1e-25 88.6 14.0 5.6e-25 88.5 14.0 1.0 1 0 0 1 1 1 1 Outer membrane protein beta-barrel domain OmpA_membrane PF01389.17 AIM21019.1 - 0.00024 20.9 0.8 0.00051 19.8 0.8 1.7 1 1 0 1 1 1 1 OmpA-like transmembrane domain Porin_7 PF16956.5 AIM21019.1 - 0.00028 20.6 1.7 0.041 13.5 1.6 2.1 1 1 1 2 2 2 2 Putative general bacterial porin MOSP_C PF02722.15 AIM21019.1 - 0.047 13.4 0.0 0.07 12.8 0.0 1.3 1 0 0 1 1 1 0 Major Outer Sheath Protein C-terminal domain CN_hydrolase PF00795.22 AIM21020.1 - 1.7e-42 145.6 0.0 5.9e-41 140.5 0.0 2.0 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase LysR_substrate PF03466.20 AIM21021.1 - 4.9e-28 97.9 7.7 4.9e-28 97.9 7.7 1.5 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AIM21021.1 - 3.2e-20 71.8 1.5 3.2e-20 71.8 1.5 2.2 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family Acetyltransf_3 PF13302.7 AIM21022.1 - 1.5e-27 97.0 0.0 1.7e-27 96.8 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AIM21022.1 - 1.5e-05 25.2 0.0 2.3e-05 24.6 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 AIM21022.1 - 0.11 12.5 0.0 0.3 11.1 0.0 1.7 2 0 0 2 2 2 0 FR47-like protein GntP_permease PF02447.16 AIM21023.1 - 1.3e-147 492.1 43.0 1.5e-147 491.8 43.0 1.0 1 0 0 1 1 1 1 GntP family permease CitMHS PF03600.16 AIM21023.1 - 7.2e-19 68.1 37.5 1.3e-18 67.3 37.5 1.4 1 0 0 1 1 1 1 Citrate transporter DctM PF06808.12 AIM21023.1 - 0.038 12.8 41.1 0.35 9.6 19.6 2.3 1 1 1 2 2 2 0 Tripartite ATP-independent periplasmic transporter, DctM component AP_endonuc_2 PF01261.24 AIM21024.1 - 1.1e-33 116.4 0.6 1.3e-33 116.2 0.6 1.0 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Aldolase_II PF00596.21 AIM21025.1 - 1e-41 143.0 0.0 1.2e-41 142.8 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain SBD_N PF07005.11 AIM21026.1 - 5.6e-69 232.3 0.1 9.4e-69 231.6 0.1 1.4 1 0 0 1 1 1 1 Sugar-binding N-terminal domain NBD_C PF17042.5 AIM21026.1 - 2e-40 139.1 0.4 2e-40 139.1 0.4 2.4 3 0 0 3 3 3 1 Nucleotide-binding C-terminal domain LnmK_N_HDF PF18238.1 AIM21026.1 - 0.094 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 LnmK N-terminal Hot Dog Fold domain NAD_binding_2 PF03446.15 AIM21027.1 - 1e-38 133.0 2.7 1.6e-38 132.3 2.7 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 AIM21027.1 - 1e-33 116.1 0.7 1e-33 116.1 0.7 1.8 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 3HCDH_N PF02737.18 AIM21027.1 - 2.4e-05 24.3 0.9 0.00037 20.4 0.4 2.3 1 1 1 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 AIM21027.1 - 4.8e-05 23.9 0.3 0.00011 22.7 0.3 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 AIM21027.1 - 0.00054 19.3 0.5 0.0009 18.6 0.5 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 AIM21027.1 - 0.025 13.9 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 AIM21027.1 - 0.26 11.3 3.7 0.19 11.7 0.7 2.1 2 0 0 2 2 2 0 Zinc-binding dehydrogenase DeoRC PF00455.22 AIM21028.1 - 7.2e-50 169.1 0.1 1e-49 168.6 0.1 1.2 1 0 0 1 1 1 1 DeoR C terminal sensor domain HTH_DeoR PF08220.12 AIM21028.1 - 8.4e-18 63.9 0.4 1.5e-17 63.1 0.4 1.4 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 AIM21028.1 - 9.1e-12 44.7 0.2 1.6e-11 44.0 0.2 1.4 1 0 0 1 1 1 1 HTH domain HTH_24 PF13412.6 AIM21028.1 - 2.3e-06 27.1 0.2 2.9e-05 23.5 0.1 2.2 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding GntR PF00392.21 AIM21028.1 - 4.4e-05 23.1 0.3 0.00012 21.7 0.3 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Rrf2 PF02082.20 AIM21028.1 - 7.1e-05 23.1 0.2 0.00015 22.0 0.2 1.4 1 0 0 1 1 1 1 Transcriptional regulator MarR_2 PF12802.7 AIM21028.1 - 0.00014 21.7 0.4 0.00037 20.3 0.4 1.7 1 0 0 1 1 1 1 MarR family Fe_dep_repress PF01325.19 AIM21028.1 - 0.00014 22.0 0.2 0.00028 21.0 0.2 1.4 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain MarR PF01047.22 AIM21028.1 - 0.00014 21.7 0.1 0.00029 20.7 0.1 1.5 1 0 0 1 1 1 1 MarR family HTH_23 PF13384.6 AIM21028.1 - 0.00039 20.1 0.1 0.00078 19.2 0.1 1.5 1 0 0 1 1 1 1 Homeodomain-like domain TrmB PF01978.19 AIM21028.1 - 0.00068 19.5 0.1 0.0015 18.4 0.1 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.7 AIM21028.1 - 0.0016 18.5 1.8 0.0024 17.9 0.1 2.2 3 0 0 3 3 2 1 Helix-turn-helix domain HTH_AsnC-type PF13404.6 AIM21028.1 - 0.0063 16.3 1.0 0.013 15.3 0.4 1.8 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain AbiEi_4 PF13338.6 AIM21028.1 - 0.0066 16.6 0.0 0.017 15.3 0.0 1.7 1 0 0 1 1 1 1 Transcriptional regulator, AbiEi antitoxin Sigma70_r4 PF04545.16 AIM21028.1 - 0.0073 15.8 0.7 0.02 14.4 0.7 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_Mga PF08280.11 AIM21028.1 - 0.0076 16.3 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 M protein trans-acting positive regulator (MGA) HTH domain HTH_28 PF13518.6 AIM21028.1 - 0.0081 16.3 0.1 0.021 14.9 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.10 AIM21028.1 - 0.012 15.4 0.2 0.022 14.5 0.2 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain DDRGK PF09756.9 AIM21028.1 - 0.017 14.7 0.1 0.025 14.2 0.1 1.2 1 0 0 1 1 1 0 DDRGK domain PaaX PF07848.12 AIM21028.1 - 0.038 14.2 0.1 0.077 13.2 0.1 1.4 1 0 0 1 1 1 0 PaaX-like protein HTH_5 PF01022.20 AIM21028.1 - 0.05 13.5 0.2 0.1 12.5 0.2 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Adeno_PIX PF03955.14 AIM21028.1 - 0.054 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) HTH_38 PF13936.6 AIM21028.1 - 0.081 12.7 0.1 0.22 11.3 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain DUF742 PF05331.11 AIM21028.1 - 0.1 12.4 0.3 1.8 8.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF742) DprA_WH PF17782.1 AIM21028.1 - 0.1 12.7 1.6 0.85 9.8 0.4 2.3 2 0 0 2 2 2 0 DprA winged helix domain HTH_36 PF13730.6 AIM21028.1 - 0.11 12.4 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain FeoC PF09012.10 AIM21028.1 - 0.14 12.2 0.1 0.33 11.1 0.1 1.6 1 0 0 1 1 1 0 FeoC like transcriptional regulator HTH_Tnp_ISL3 PF13542.6 AIM21028.1 - 0.15 11.5 0.2 0.42 10.0 0.2 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Mga PF05043.13 AIM21028.1 - 0.2 12.3 0.1 0.57 10.8 0.0 1.7 2 0 0 2 2 1 0 Mga helix-turn-helix domain PriA_C PF18074.1 AIM21029.1 - 0.02 15.7 0.3 0.7 10.7 0.1 2.2 2 0 0 2 2 2 0 Primosomal protein N C-terminal domain Oxidored_molyb PF00174.19 AIM21030.1 - 4.3e-34 117.6 0.0 6.1e-34 117.1 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Ni_hydr_CYTB PF01292.20 AIM21031.1 - 1.7e-22 79.9 22.9 2e-22 79.7 22.9 1.1 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 DUF4405 PF14358.6 AIM21031.1 - 0.051 14.1 10.6 0.051 14.1 10.6 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4405) ArsA_HSP20 PF17886.1 AIM21032.1 - 0.048 13.2 0.1 0.66 9.6 0.0 2.2 2 0 0 2 2 2 0 HSP20-like domain found in ArsA TcpQ PF10671.9 AIM21032.1 - 0.093 12.9 0.1 1.4 9.1 0.0 2.2 2 0 0 2 2 2 0 Toxin co-regulated pilus biosynthesis protein Q Prot_ATP_OB_N PF17758.1 AIM21032.1 - 0.11 12.2 0.2 0.69 9.6 0.1 2.3 2 1 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain Trans_reg_C PF00486.28 AIM21033.1 - 1.8e-25 88.8 0.2 4.2e-25 87.6 0.0 1.7 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal Response_reg PF00072.24 AIM21033.1 - 6.8e-23 81.0 0.0 1e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 AIM21034.1 - 5.2e-16 59.1 0.0 9.5e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 AIM21034.1 - 9.5e-12 45.1 1.2 2.7e-11 43.7 0.2 2.4 2 0 0 2 2 2 1 HAMP domain HisKA PF00512.25 AIM21034.1 - 8.9e-11 41.7 0.1 3.3e-10 39.9 0.1 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 AIM21034.1 - 0.013 15.4 0.0 0.041 13.8 0.0 1.8 1 1 0 1 1 1 0 Histidine kinase-like ATPase domain Ferlin_C PF16165.5 AIM21034.1 - 0.045 13.7 0.0 0.079 12.9 0.0 1.3 1 0 0 1 1 1 0 Ferlin C-terminus HATPase_c_5 PF14501.6 AIM21034.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 GHKL domain HATPase_c PF02518.26 AIM21035.1 - 5e-18 65.6 0.0 8.7e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AIM21035.1 - 3.4e-14 52.6 1.5 1e-13 51.1 0.4 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AIM21035.1 - 1.6e-10 41.2 0.1 7.5e-10 39.0 0.0 2.3 2 0 0 2 2 2 1 HAMP domain HATPase_c_2 PF13581.6 AIM21035.1 - 1.4e-05 25.0 0.0 3.4e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain dCache_1 PF02743.18 AIM21035.1 - 0.00016 21.5 0.0 0.00027 20.8 0.0 1.3 1 0 0 1 1 1 1 Cache domain HATPase_c_5 PF14501.6 AIM21035.1 - 0.045 13.7 0.0 0.093 12.6 0.0 1.5 1 0 0 1 1 1 0 GHKL domain PE PF00934.20 AIM21035.1 - 0.052 13.9 1.2 0.097 13.0 0.2 2.0 2 0 0 2 2 2 0 PE family Enkurin PF13864.6 AIM21035.1 - 0.15 12.5 0.1 0.27 11.7 0.1 1.4 1 0 0 1 1 1 0 Calmodulin-binding LapA_dom PF06305.11 AIM21035.1 - 0.35 10.7 1.8 28 4.6 0.1 2.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Trans_reg_C PF00486.28 AIM21036.1 - 1.6e-27 95.4 0.0 2.9e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Response_reg PF00072.24 AIM21036.1 - 1.7e-25 89.3 0.0 2.4e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain DUF1848 PF08902.11 AIM21036.1 - 0.068 12.9 0.0 2.9 7.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1848) MarR_2 PF12802.7 AIM21036.1 - 0.14 12.0 0.4 1.1 9.2 0.0 2.5 3 0 0 3 3 3 0 MarR family Ni_hydr_CYTB PF01292.20 AIM21037.1 - 7.7e-26 90.8 18.8 8.8e-26 90.6 18.8 1.0 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 DUF4405 PF14358.6 AIM21037.1 - 0.0001 22.8 7.2 0.0001 22.8 7.2 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4405) Oxidored_molyb PF00174.19 AIM21038.1 - 2.1e-31 108.9 0.0 2.8e-31 108.4 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain BCCT PF02028.17 AIM21040.1 - 8.4e-173 575.3 43.5 9.9e-173 575.0 43.5 1.0 1 0 0 1 1 1 1 BCCT, betaine/carnitine/choline family transporter TetR_C_6 PF13977.6 AIM21041.1 - 7.8e-32 109.9 2.4 7.8e-32 109.9 2.4 1.9 2 0 0 2 2 2 1 BetI-type transcriptional repressor, C-terminal TetR_N PF00440.23 AIM21041.1 - 3.1e-13 49.3 0.1 5.3e-13 48.5 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family DUF1744 PF08490.12 AIM21041.1 - 0.011 14.3 0.0 0.016 13.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) LacI PF00356.21 AIM21041.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family TetR_C_31 PF17940.1 AIM21041.1 - 0.69 10.1 4.0 0.37 11.0 0.8 2.1 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Aldedh PF00171.22 AIM21042.1 - 7.1e-179 595.1 0.7 8e-179 595.0 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GMC_oxred_N PF00732.19 AIM21043.1 - 2.7e-99 332.3 0.0 3.6e-99 331.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 AIM21043.1 - 5.4e-41 140.5 0.0 8.2e-41 139.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 AIM21043.1 - 0.0026 16.9 0.0 0.0043 16.2 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 AIM21043.1 - 0.0027 16.9 0.4 0.28 10.2 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 AIM21043.1 - 0.0054 16.9 0.2 0.013 15.7 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AIM21043.1 - 0.0069 16.0 0.1 0.58 9.7 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 AIM21043.1 - 0.031 13.5 0.0 0.081 12.1 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 AIM21043.1 - 0.051 12.8 0.1 0.12 11.6 0.1 1.6 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 AIM21043.1 - 0.17 10.5 0.1 0.42 9.2 0.1 1.5 2 0 0 2 2 2 0 HI0933-like protein Glu_synthase PF01645.17 AIM21044.1 - 6.4e-85 285.5 0.1 8.3e-85 285.1 0.1 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase FMN_dh PF01070.18 AIM21044.1 - 0.013 14.5 0.2 0.031 13.3 0.1 1.6 2 0 0 2 2 2 0 FMN-dependent dehydrogenase 7TM-7TMR_HD PF07698.11 AIM21044.1 - 0.088 12.6 0.5 0.15 11.9 0.5 1.3 1 0 0 1 1 1 0 7TM receptor with intracellular HD hydrolase DUF4131 PF13567.6 AIM21044.1 - 0.8 9.3 3.4 1.6 8.4 3.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) GerE PF00196.19 AIM21045.1 - 9.3e-05 21.9 0.0 0.00017 21.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family DUF4941 PF16299.5 AIM21045.1 - 0.013 14.9 0.1 0.016 14.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4941) Ist1 PF03398.14 AIM21045.1 - 0.077 12.9 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway EAL PF00563.20 AIM21046.1 - 1.7e-28 99.8 0.0 2.1e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 EAL domain Cag12 PF13117.6 AIM21046.1 - 0.026 15.0 0.4 0.11 13.0 0.1 2.0 2 0 0 2 2 2 0 Cag pathogenicity island protein Cag12 Fimbrial PF00419.20 AIM21047.1 - 6e-14 52.6 1.6 7.2e-14 52.3 1.6 1.0 1 0 0 1 1 1 1 Fimbrial protein FlgD_ig PF13860.6 AIM21047.1 - 0.038 13.9 0.3 1.7 8.6 0.0 2.7 3 0 0 3 3 3 0 FlgD Ig-like domain DUF3747 PF12565.8 AIM21047.1 - 0.12 11.7 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3747) Big_3_5 PF16640.5 AIM21047.1 - 0.18 12.0 3.8 0.27 11.4 3.8 1.4 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) PapD_N PF00345.20 AIM21048.1 - 1.8e-39 134.4 0.1 2.7e-39 133.9 0.1 1.3 1 0 0 1 1 1 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain PapD_C PF02753.17 AIM21048.1 - 5.4e-12 45.9 0.1 1.1e-11 44.9 0.1 1.6 1 0 0 1 1 1 1 Pili assembly chaperone PapD, C-terminal domain DnaJ_C PF01556.18 AIM21048.1 - 0.12 12.5 0.0 0.13 12.4 0.0 1.4 1 1 0 1 1 1 0 DnaJ C terminal domain Usher PF00577.20 AIM21049.1 - 1.5e-181 605.0 26.3 2.1e-181 604.6 26.3 1.2 1 0 0 1 1 1 1 Outer membrane usher protein PapC_N PF13954.6 AIM21049.1 - 7.2e-37 126.6 0.5 2e-36 125.2 0.1 1.9 2 0 0 2 2 2 1 PapC N-terminal domain PapC_C PF13953.6 AIM21049.1 - 3.2e-10 39.7 0.0 8.8e-10 38.3 0.0 1.8 1 0 0 1 1 1 1 PapC C-terminal domain Fimbrial PF00419.20 AIM21050.1 - 7.8e-21 74.9 9.2 7.4e-20 71.8 6.1 2.2 2 0 0 2 2 2 2 Fimbrial protein HTH_18 PF12833.7 AIM21051.1 - 3.2e-22 78.6 1.4 4.1e-22 78.2 1.4 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AIM21051.1 - 4.6e-16 58.5 0.2 5.1e-10 39.2 0.1 2.2 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Mqo PF06039.15 AIM21052.1 - 1.8e-241 801.8 0.0 2.1e-241 801.6 0.0 1.0 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) DAO PF01266.24 AIM21052.1 - 8.2e-06 25.6 0.0 1.7e-05 24.6 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 AIM21052.1 - 0.033 13.3 0.1 1.1 8.4 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Alk_phosphatase PF00245.20 AIM21053.1 - 3.1e-129 431.6 5.7 4.5e-121 404.7 2.9 2.0 1 1 1 2 2 2 2 Alkaline phosphatase Metalloenzyme PF01676.18 AIM21053.1 - 9.9e-07 28.4 0.4 9.4e-06 25.2 0.3 2.1 2 0 0 2 2 2 1 Metalloenzyme superfamily Sulfatase PF00884.23 AIM21053.1 - 0.032 13.6 0.7 0.47 9.8 0.1 2.7 2 2 1 3 3 3 0 Sulfatase GST_N PF02798.20 AIM21054.1 - 2e-14 53.6 0.0 4.5e-14 52.5 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 AIM21054.1 - 3.1e-12 46.7 0.0 5.5e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AIM21054.1 - 2.2e-11 43.9 0.0 4.7e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 AIM21054.1 - 9.1e-10 38.6 0.1 1.9e-09 37.6 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 AIM21054.1 - 2.5e-09 37.2 0.0 3.9e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 AIM21054.1 - 1.9e-08 34.2 0.2 6e-08 32.6 0.1 1.8 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 AIM21054.1 - 0.088 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain HTH_5 PF01022.20 AIM21055.1 - 5.6e-10 38.9 0.1 1.1e-09 38.0 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 AIM21055.1 - 9.6e-10 38.4 4.1 1.6e-09 37.7 2.4 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.7 AIM21055.1 - 0.00083 19.2 2.3 0.0074 16.2 0.5 2.7 2 0 0 2 2 2 1 MarR family HTH_24 PF13412.6 AIM21055.1 - 0.0015 18.1 0.0 0.0033 17.0 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 AIM21055.1 - 0.002 18.0 0.2 0.025 14.5 0.0 2.3 2 0 0 2 2 2 1 MarR family HTH_34 PF13601.6 AIM21055.1 - 0.002 18.2 0.0 0.15 12.2 0.0 2.3 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_IclR PF09339.10 AIM21055.1 - 0.027 14.3 3.6 0.1 12.4 1.2 2.7 3 0 0 3 3 3 0 IclR helix-turn-helix domain Fe_dep_repress PF01325.19 AIM21055.1 - 0.056 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain TrmB PF01978.19 AIM21055.1 - 0.1 12.5 0.1 0.24 11.3 0.0 1.6 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HlyC PF02794.16 AIM21055.1 - 0.17 11.7 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 RTX toxin acyltransferase family ABM PF03992.16 AIM21056.1 - 3.3e-17 62.4 0.1 4.9e-17 61.8 0.1 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DDE_Tnp_1_5 PF13737.6 AIM21056.1 - 0.11 12.9 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Transposase DDE domain AAA_33 PF13671.6 AIM21057.1 - 6.3e-28 97.7 0.0 7.1e-28 97.6 0.0 1.0 1 0 0 1 1 1 1 AAA domain dNK PF01712.19 AIM21057.1 - 3.7e-05 23.7 0.0 0.16 11.8 0.0 2.1 2 0 0 2 2 2 2 Deoxynucleoside kinase AAA_18 PF13238.6 AIM21057.1 - 0.0011 19.5 0.0 0.003 18.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AIM21057.1 - 0.0029 17.9 0.0 0.0051 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 AIM21057.1 - 0.0056 16.4 0.0 0.0066 16.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 AIM21057.1 - 0.0059 16.5 0.0 0.0093 15.9 0.0 1.4 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.22 AIM21057.1 - 0.0084 16.5 0.0 0.019 15.3 0.0 1.6 1 1 0 1 1 1 1 RNA helicase AAA_16 PF13191.6 AIM21057.1 - 0.014 15.8 0.1 0.024 15.0 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 AIM21057.1 - 0.02 14.8 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Zeta_toxin PF06414.12 AIM21057.1 - 0.021 14.1 0.1 0.034 13.4 0.1 1.6 1 1 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 AIM21057.1 - 0.038 14.5 0.0 0.038 14.5 0.0 1.4 1 1 0 1 1 1 0 ABC transporter Mg_chelatase PF01078.21 AIM21057.1 - 0.057 12.8 0.0 0.077 12.4 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Ploopntkinase1 PF18748.1 AIM21057.1 - 0.092 12.3 0.0 3.9 7.0 0.0 2.1 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 SKI PF01202.22 AIM21057.1 - 0.14 12.3 0.0 0.57 10.3 0.0 1.9 2 0 0 2 2 2 0 Shikimate kinase AAA_17 PF13207.6 AIM21057.1 - 0.14 12.6 0.0 0.72 10.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 AIM21057.1 - 0.17 12.4 0.0 1 9.8 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 AIM21057.1 - 0.17 11.6 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cytidylate_kin PF02224.18 AIM21057.1 - 0.22 11.2 0.0 0.31 10.7 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase PduV-EutP PF10662.9 AIM21057.1 - 0.25 11.1 0.1 0.53 10.0 0.1 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Acetyltransf_1 PF00583.25 AIM21058.1 - 2.6e-10 40.6 0.0 3.3e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AIM21058.1 - 1.6e-08 34.9 0.0 2.2e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AIM21058.1 - 2e-08 34.4 0.0 2.9e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AIM21058.1 - 0.00026 20.9 0.0 0.00053 19.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AIM21058.1 - 0.0052 16.7 0.0 0.0099 15.8 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein YjhX_toxin PF09857.9 AIM21059.1 - 1.4e-40 137.1 0.1 1.6e-40 137.0 0.1 1.0 1 0 0 1 1 1 1 Putative toxin of bacterial toxin-antitoxin pair Cyanate_lyase PF02560.14 AIM21060.1 - 5.1e-32 109.5 0.0 9e-32 108.7 0.0 1.4 2 0 0 2 2 2 1 Cyanate lyase C-terminal domain HTH_31 PF13560.6 AIM21060.1 - 0.0023 18.2 0.2 0.0037 17.6 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Pro_CA PF00484.19 AIM21061.1 - 1.1e-48 165.4 0.0 1.3e-48 165.2 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase LysR_substrate PF03466.20 AIM21062.1 - 4.9e-45 153.5 9.3 6.9e-45 153.0 9.3 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM21062.1 - 3e-28 97.6 1.6 5.5e-28 96.7 0.4 2.2 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AIM21062.1 - 9.5e-07 28.5 0.1 9.5e-07 28.5 0.1 2.3 3 0 0 3 3 3 1 PucR C-terminal helix-turn-helix domain HTH_28 PF13518.6 AIM21062.1 - 0.0026 17.9 0.1 0.013 15.6 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_5 PF01022.20 AIM21062.1 - 0.0038 17.1 0.0 0.0076 16.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 AIM21062.1 - 0.04 14.0 0.1 0.13 12.3 0.1 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain MarR PF01047.22 AIM21062.1 - 0.054 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 MarR family DUF2089 PF09862.9 AIM21062.1 - 0.081 13.0 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) HTH_24 PF13412.6 AIM21062.1 - 0.15 11.6 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 AIM21062.1 - 0.2 11.6 0.1 0.2 11.6 0.1 2.6 4 0 0 4 4 4 0 MarR family HxlR PF01638.17 AIM21064.1 - 1.5e-20 72.8 0.1 1.9e-20 72.5 0.1 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix PadR PF03551.14 AIM21064.1 - 0.0014 18.5 0.2 0.0023 17.8 0.2 1.2 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family MarR_2 PF12802.7 AIM21064.1 - 0.0085 16.0 0.1 0.015 15.2 0.1 1.4 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 AIM21064.1 - 0.033 14.3 0.1 0.086 12.9 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_27 PF13463.6 AIM21064.1 - 0.091 13.3 0.1 0.14 12.7 0.1 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_45 PF14947.6 AIM21064.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix HTH_34 PF13601.6 AIM21064.1 - 0.16 12.2 0.0 0.26 11.5 0.0 1.2 1 0 0 1 1 1 0 Winged helix DNA-binding domain Tautomerase PF01361.21 AIM21065.1 - 9.7e-12 44.6 0.0 1.9e-11 43.7 0.0 1.5 1 1 0 1 1 1 1 Tautomerase enzyme Tautomerase_3 PF14832.6 AIM21065.1 - 0.033 14.4 0.0 0.04 14.2 0.0 1.1 1 0 0 1 1 1 0 Putative oxalocrotonate tautomerase enzyme ABC_tran PF00005.27 AIM21066.1 - 6e-45 153.1 0.0 4.3e-23 82.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 AIM21066.1 - 8.8e-24 83.4 4.1 5.1e-21 74.5 2.4 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 AIM21066.1 - 4.5e-12 46.4 15.6 0.0013 18.6 0.0 4.7 4 1 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIM21066.1 - 2.8e-07 30.2 8.8 0.052 13.0 0.1 4.3 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain RNA_helicase PF00910.22 AIM21066.1 - 6.7e-06 26.4 0.0 0.24 11.8 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.6 AIM21066.1 - 2.6e-05 24.5 0.0 0.05 13.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 AIM21066.1 - 2.8e-05 23.9 0.1 0.11 12.2 0.1 2.8 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 AIM21066.1 - 9.8e-05 22.3 0.4 0.035 14.0 0.0 2.8 3 0 0 3 3 3 1 RsgA GTPase AAA_29 PF13555.6 AIM21066.1 - 0.00013 21.6 0.8 0.5 10.1 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 AIM21066.1 - 0.00017 21.6 0.0 0.12 12.4 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_14 PF13173.6 AIM21066.1 - 0.00018 21.5 0.0 0.69 10.0 0.0 3.6 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 AIM21066.1 - 0.00034 20.6 4.5 0.032 14.2 0.2 3.1 3 0 0 3 3 2 1 NACHT domain DUF87 PF01935.17 AIM21066.1 - 0.00034 20.8 4.5 2.3 8.2 0.1 3.8 4 0 0 4 4 4 2 Helicase HerA, central domain MeaB PF03308.16 AIM21066.1 - 0.0004 19.5 1.1 0.0083 15.1 0.0 2.8 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 AIM21066.1 - 0.00079 19.8 0.1 0.12 12.8 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.6 AIM21066.1 - 0.0015 18.7 0.1 3.9 7.6 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 AIM21066.1 - 0.0035 17.9 0.3 3.1 8.3 0.0 2.9 3 0 0 3 3 2 1 AAA domain SbcCD_C PF13558.6 AIM21066.1 - 0.0056 16.9 0.2 7.1 6.9 0.1 3.3 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.22 AIM21066.1 - 0.011 15.0 3.8 0.02 14.1 0.1 2.4 2 1 0 2 2 2 0 NB-ARC domain AAA PF00004.29 AIM21066.1 - 0.015 15.7 2.2 5.5 7.4 0.2 3.5 4 1 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.25 AIM21066.1 - 0.02 14.5 0.1 3.7 7.2 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Septin PF00735.18 AIM21066.1 - 0.029 13.6 0.3 0.54 9.5 0.0 2.3 2 0 0 2 2 2 0 Septin AAA_22 PF13401.6 AIM21066.1 - 0.039 14.2 4.4 1.9 8.7 0.5 3.8 3 1 0 3 3 3 0 AAA domain PduV-EutP PF10662.9 AIM21066.1 - 0.085 12.6 0.3 4.3 7.1 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_15 PF13175.6 AIM21066.1 - 0.089 12.5 11.2 0.15 11.8 0.5 3.4 3 1 0 4 4 4 0 AAA ATPase domain AAA_30 PF13604.6 AIM21066.1 - 0.092 12.5 0.0 5.6 6.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 AIM21066.1 - 0.096 12.6 0.6 4.3 7.2 0.0 2.8 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea Roc PF08477.13 AIM21066.1 - 0.11 12.7 3.5 0.33 11.2 0.0 3.1 4 0 0 4 4 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 AIM21066.1 - 0.12 11.9 1.7 15 5.1 0.0 3.0 3 1 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.18 AIM21066.1 - 0.12 11.7 1.5 1.3 8.3 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_7 PF12775.7 AIM21066.1 - 0.16 11.5 1.4 1.1 8.7 0.1 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region MukB PF04310.12 AIM21066.1 - 0.16 11.7 0.5 14 5.4 0.0 2.6 2 0 0 2 2 2 0 MukB N-terminal BRE1 PF08647.11 AIM21066.1 - 0.2 11.8 5.0 0.41 10.7 5.0 1.5 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Dynamin_N PF00350.23 AIM21066.1 - 0.27 11.3 3.0 4.1 7.4 0.0 2.9 3 0 0 3 3 3 0 Dynamin family AAA_23 PF13476.6 AIM21066.1 - 1.5 9.2 16.0 1.1 9.7 0.8 3.4 3 1 0 3 3 3 0 AAA domain AAA_5 PF07728.14 AIM21066.1 - 2.5 8.1 6.0 72 3.4 0.2 3.9 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 AIM21066.1 - 7 6.5 5.8 10 6.0 0.2 3.5 4 0 0 4 4 4 0 NTPase ThiF PF00899.21 AIM21067.1 - 3.7e-64 216.4 0.1 4.4e-64 216.2 0.1 1.0 1 0 0 1 1 1 1 ThiF family NAD_binding_7 PF13241.6 AIM21067.1 - 0.0024 18.3 0.1 0.0043 17.5 0.1 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 AIM21067.1 - 0.03 14.6 0.9 0.12 12.7 0.9 1.8 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 AIM21067.1 - 0.076 12.6 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MoeA_N PF03453.17 AIM21068.1 - 3.7e-46 156.8 2.7 5.9e-46 156.1 2.7 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 AIM21068.1 - 1.5e-26 92.8 0.0 2.2e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_C PF03454.15 AIM21068.1 - 1.4e-18 66.8 0.0 3.5e-18 65.6 0.0 1.7 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) Motilin_assoc PF04643.12 AIM21068.1 - 0.022 14.6 0.7 4.7 7.1 0.2 2.6 2 0 0 2 2 2 0 Motilin/ghrelin-associated peptide DUF1566 PF07603.11 AIM21068.1 - 0.1 13.0 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1566) DUF924 PF06041.11 AIM21069.1 - 6.1e-60 202.5 0.1 6.8e-60 202.3 0.1 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Asparaginase_2 PF01112.18 AIM21070.1 - 2.7e-119 397.8 6.7 3e-119 397.6 6.7 1.0 1 0 0 1 1 1 1 Asparaginase PCP_red PF08369.10 AIM21070.1 - 0.056 13.7 0.0 0.27 11.5 0.0 2.1 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit SelB-wing_1 PF09105.10 AIM21070.1 - 0.063 13.3 1.0 0.29 11.1 1.0 2.1 2 0 0 2 2 2 0 Elongation factor SelB, winged helix ABC_tran PF00005.27 AIM21071.1 - 5.9e-60 201.7 0.0 2.1e-32 112.5 0.0 2.3 2 0 0 2 2 2 2 ABC transporter oligo_HPY PF08352.12 AIM21071.1 - 4.1e-15 56.0 0.1 2.4e-08 34.4 0.1 2.4 2 0 0 2 2 2 2 Oligopeptide/dipeptide transporter, C-terminal region SMC_N PF02463.19 AIM21071.1 - 6.4e-10 38.8 2.7 3.7e-05 23.3 0.6 3.6 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AIM21071.1 - 8.3e-10 39.1 4.8 3.4e-05 24.1 0.1 3.9 2 2 0 2 2 2 2 AAA domain AAA_21 PF13304.6 AIM21071.1 - 9e-08 32.3 0.8 0.0014 18.5 0.0 3.8 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AIM21071.1 - 6.2e-06 26.7 1.6 0.04 14.3 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain TniB PF05621.11 AIM21071.1 - 3.3e-05 23.4 1.7 0.47 9.8 0.2 4.0 4 0 0 4 4 4 1 Bacterial TniB protein AAA_29 PF13555.6 AIM21071.1 - 6.6e-05 22.6 0.4 0.11 12.3 0.1 2.3 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 AIM21071.1 - 0.00049 19.9 0.5 0.083 12.6 0.0 2.6 3 0 0 3 3 2 1 AAA domain ATP-synt_ab PF00006.25 AIM21071.1 - 0.0012 18.5 0.1 0.75 9.4 0.0 2.5 2 1 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain RsgA_GTPase PF03193.16 AIM21071.1 - 0.0013 18.6 0.1 1.1 9.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 AIM21071.1 - 0.0093 15.5 0.7 3.3 7.2 0.1 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_25 PF13481.6 AIM21071.1 - 0.012 15.2 3.4 1.5 8.3 0.0 3.6 4 0 0 4 4 3 0 AAA domain DUF87 PF01935.17 AIM21071.1 - 0.028 14.5 3.3 2.1 8.4 0.1 2.7 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_23 PF13476.6 AIM21071.1 - 0.031 14.8 0.0 8.1 6.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 AIM21071.1 - 0.032 14.6 0.9 2.9 8.3 0.1 2.4 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 AIM21071.1 - 0.04 13.6 0.0 3.8 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 AIM21071.1 - 0.052 13.6 1.9 0.57 10.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 AIM21071.1 - 0.056 13.2 0.4 3.3 7.4 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein CbiA PF01656.23 AIM21071.1 - 0.081 13.0 4.7 0.084 12.9 0.4 2.9 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 AIM21071.1 - 0.081 13.1 0.1 9.2 6.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain AIG1 PF04548.16 AIM21071.1 - 0.089 12.1 3.5 0.33 10.2 0.3 2.5 2 0 0 2 2 2 0 AIG1 family PRK PF00485.18 AIM21071.1 - 0.12 12.1 0.5 2.2 8.0 0.0 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA PF00004.29 AIM21071.1 - 0.14 12.6 0.3 1.7 9.1 0.0 2.8 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) TrwB_AAD_bind PF10412.9 AIM21071.1 - 0.23 10.3 3.5 0.78 8.6 0.2 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Hpr_kinase_C PF07475.12 AIM21071.1 - 0.24 10.9 1.6 7.2 6.1 0.3 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain ABC_ATPase PF09818.9 AIM21071.1 - 0.34 9.6 1.2 0.99 8.1 0.4 2.1 2 1 0 2 2 2 0 Predicted ATPase of the ABC class NACHT PF05729.12 AIM21071.1 - 0.38 10.6 3.3 9.1 6.2 0.3 2.5 2 0 0 2 2 2 0 NACHT domain ATPase PF06745.13 AIM21071.1 - 0.5 9.7 2.6 12 5.1 0.0 3.0 3 0 0 3 3 3 0 KaiC SBP_bac_5 PF00496.22 AIM21072.1 - 2.2e-96 323.1 10.6 2.9e-96 322.7 10.6 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle BPD_transp_1 PF00528.22 AIM21073.1 - 8.9e-41 139.7 9.7 8.9e-41 139.7 9.7 2.2 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF2070 PF09843.9 AIM21073.1 - 1.7 6.8 5.4 1.9 6.7 5.4 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) BPD_transp_1 PF00528.22 AIM21074.1 - 9.9e-31 106.9 11.6 9.9e-31 106.9 11.6 1.8 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 AIM21074.1 - 1.6e-13 50.4 0.2 1.6e-13 50.4 0.2 3.3 3 1 0 3 3 3 1 N-terminal TM domain of oligopeptide transport permease C Apelin PF15360.6 AIM21074.1 - 0.23 12.0 0.6 0.41 11.2 0.6 1.3 1 0 0 1 1 1 0 APJ endogenous ligand DUF3482 PF11981.8 AIM21074.1 - 4.9 6.4 4.3 1.8 7.9 2.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3482) Neurensin PF14927.6 AIM21074.1 - 7.7 6.2 0.0 7.7 6.2 0.0 2.8 4 0 0 4 4 4 0 Neurensin CcdA PF07362.12 AIM21075.1 - 4.7e-25 87.8 0.7 5.3e-25 87.6 0.7 1.0 1 0 0 1 1 1 1 Post-segregation antitoxin CcdA Nrap_D3 PF17404.2 AIM21075.1 - 0.037 14.1 0.1 0.037 14.1 0.1 1.1 1 0 0 1 1 1 0 Nrap protein domain 3 PPP1R35_C PF15503.6 AIM21075.1 - 0.1 12.4 0.5 0.12 12.1 0.5 1.1 1 0 0 1 1 1 0 Protein phosphatase 1 regulatory subunit 35 C-terminus CcdB PF01845.17 AIM21076.1 - 2.3e-33 114.4 0.1 2.6e-33 114.2 0.1 1.0 1 0 0 1 1 1 1 CcdB protein Esterase PF00756.20 AIM21077.1 - 9.9e-67 225.2 0.0 1.2e-66 224.9 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 AIM21077.1 - 3.1e-08 33.4 0.0 4.4e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 AIM21077.1 - 2.3e-05 23.8 0.2 0.00081 18.7 0.1 2.1 1 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AIM21077.1 - 4.9e-05 24.0 3.3 0.00043 21.0 0.9 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Esterase_phd PF10503.9 AIM21077.1 - 0.0001 21.9 0.0 0.0023 17.5 0.0 2.4 1 1 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_1 PF00561.20 AIM21077.1 - 0.00017 21.3 0.2 0.0025 17.5 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Tannase PF07519.11 AIM21077.1 - 0.053 12.4 0.0 0.066 12.1 0.0 1.1 1 0 0 1 1 1 0 Tannase and feruloyl esterase Chlorophyllase2 PF12740.7 AIM21077.1 - 0.053 12.4 0.0 0.064 12.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DLH PF01738.18 AIM21077.1 - 0.054 13.0 0.0 0.13 11.8 0.0 1.6 1 1 0 1 1 1 0 Dienelactone hydrolase family Lipase_3 PF01764.25 AIM21077.1 - 0.084 12.7 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) ADH_N PF08240.12 AIM21078.1 - 3e-25 88.2 0.6 7.7e-25 86.9 0.6 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AIM21078.1 - 1.3e-24 86.6 0.1 2.4e-24 85.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 AIM21078.1 - 0.00011 21.8 0.0 0.00066 19.2 0.0 2.0 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 AIM21078.1 - 0.00065 20.8 0.0 0.0018 19.3 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 AIM21078.1 - 0.037 13.6 0.2 0.056 13.0 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain LysR_substrate PF03466.20 AIM21079.1 - 2.9e-37 128.1 1.2 3.9e-37 127.7 1.2 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM21079.1 - 4.9e-18 64.8 0.4 1.2e-17 63.5 0.4 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AIM21079.1 - 0.00037 20.2 0.2 0.0012 18.6 0.2 1.8 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain MFS_4 PF06779.14 AIM21080.1 - 5e-86 289.3 40.6 5.8e-86 289.1 40.6 1.0 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1 PF07690.16 AIM21080.1 - 6.9e-11 41.7 41.1 6.9e-11 41.7 41.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF630 PF04783.12 AIM21080.1 - 0.098 12.8 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF630) stn_TNFRSF12A PF12191.8 AIM21080.1 - 1.7 8.8 7.6 0.29 11.3 0.4 3.0 2 1 1 3 3 3 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain GTP_cyclohydroI PF01227.22 AIM21081.1 - 1.1e-58 197.6 0.2 1.4e-58 197.3 0.2 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 AIM21081.1 - 0.022 14.9 0.0 0.042 14.0 0.0 1.4 1 0 0 1 1 1 0 QueF-like protein DUF418 PF04235.12 AIM21082.1 - 9.1e-46 155.8 17.6 9.1e-46 155.8 17.6 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF418) Peripla_BP_3 PF13377.6 AIM21083.1 - 6.7e-35 120.9 2.0 1.8e-34 119.4 0.1 2.3 2 1 1 3 3 3 1 Periplasmic binding protein-like domain LacI PF00356.21 AIM21083.1 - 1.4e-20 72.8 0.8 3.2e-20 71.7 0.8 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_1 PF00532.21 AIM21083.1 - 2.5e-20 73.1 0.1 2.6e-19 69.7 0.0 2.1 1 1 1 2 2 2 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_4 PF13407.6 AIM21083.1 - 1.1e-13 51.4 0.0 2.8e-13 50.1 0.0 1.7 1 1 0 1 1 1 1 Periplasmic binding protein domain HTH_31 PF13560.6 AIM21083.1 - 0.001 19.4 0.2 0.003 17.9 0.2 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_7 PF02796.15 AIM21083.1 - 0.0023 17.9 0.0 0.0071 16.4 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase Sigma54_DBD PF04552.13 AIM21083.1 - 0.0045 16.7 0.1 0.07 12.8 0.1 2.1 2 0 0 2 2 2 1 Sigma-54, DNA binding domain TetR_N PF00440.23 AIM21083.1 - 0.0049 16.6 0.0 0.021 14.6 0.0 2.1 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_38 PF13936.6 AIM21083.1 - 0.0052 16.5 1.2 0.049 13.4 0.1 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 AIM21083.1 - 0.008 15.6 0.4 0.024 14.1 0.4 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 AIM21083.1 - 0.012 15.4 0.5 0.092 12.6 0.1 2.4 1 1 1 2 2 2 0 Homeodomain-like domain HTH_3 PF01381.22 AIM21083.1 - 0.012 15.7 1.0 0.017 15.1 0.1 1.8 2 0 0 2 2 1 0 Helix-turn-helix HTH_24 PF13412.6 AIM21083.1 - 0.023 14.2 0.0 0.058 13.0 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Shadoo PF14999.6 AIM21083.1 - 0.029 14.5 0.2 0.067 13.3 0.2 1.5 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective HTH_Crp_2 PF13545.6 AIM21083.1 - 0.039 13.9 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Trp_repressor PF01371.19 AIM21083.1 - 0.075 13.2 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Trp repressor protein MarR_2 PF12802.7 AIM21083.1 - 0.089 12.7 0.3 0.57 10.1 0.0 2.5 3 0 0 3 3 3 0 MarR family NAD_binding_11 PF14833.6 AIM21083.1 - 0.1 12.8 0.9 0.32 11.2 0.1 2.1 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase MerR PF00376.23 AIM21083.1 - 0.12 12.2 0.2 0.24 11.2 0.2 1.5 1 0 0 1 1 1 0 MerR family regulatory protein MarR PF01047.22 AIM21083.1 - 0.12 12.3 0.0 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 MarR family Peripla_BP_4 PF13407.6 AIM21084.1 - 4.8e-65 219.7 12.8 5.8e-65 219.4 12.8 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 AIM21084.1 - 4.7e-12 45.9 2.9 1.8e-11 44.0 2.8 1.8 1 1 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_3 PF13377.6 AIM21084.1 - 3.8e-08 33.8 0.1 7.1e-08 33.0 0.1 1.4 1 0 0 1 1 1 1 Periplasmic binding protein-like domain PucR PF07905.11 AIM21084.1 - 0.0083 16.4 0.1 0.032 14.5 0.0 2.0 2 1 0 2 2 2 1 Purine catabolism regulatory protein-like family FSIP1 PF15554.6 AIM21084.1 - 0.078 12.1 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 FSIP1 family DUF732 PF05305.14 AIM21084.1 - 1.5 9.2 9.6 0.34 11.3 1.7 3.4 3 2 0 3 3 3 0 Protein of unknown function (DUF732) ABC_tran PF00005.27 AIM21085.1 - 4.1e-26 92.1 0.2 7.2e-17 62.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 AIM21085.1 - 0.0018 18.2 0.0 0.48 10.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 AIM21085.1 - 0.11 12.8 0.2 72 3.7 0.1 3.5 3 1 1 4 4 4 0 Putative exonuclease SbcCD, C subunit BPD_transp_2 PF02653.16 AIM21086.1 - 1.2e-49 168.9 35.8 1.2e-49 168.9 35.8 1.4 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component DUF218 PF02698.17 AIM21087.1 - 1.3e-18 67.3 0.0 2.3e-18 66.5 0.0 1.5 1 1 0 1 1 1 1 DUF218 domain Malic_M PF03949.15 AIM21088.1 - 8.2e-103 343.2 0.0 1.4e-102 342.4 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 AIM21088.1 - 3e-79 265.0 0.0 1.7e-78 262.6 0.0 2.0 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain dCMP_cyt_deam_2 PF08211.12 AIM21089.1 - 7.9e-46 155.6 4.0 4.2e-45 153.2 0.3 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_1 PF00383.23 AIM21089.1 - 1.2e-12 47.6 0.0 3.1e-11 43.0 0.0 2.2 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LrgB PF04172.16 AIM21090.1 - 7.2e-80 267.5 14.7 8.2e-80 267.3 14.7 1.0 1 0 0 1 1 1 1 LrgB-like family DUF2070 PF09843.9 AIM21090.1 - 3.1 6.0 11.1 1.1 7.5 2.7 2.0 1 1 0 2 2 2 0 Predicted membrane protein (DUF2070) LrgA PF03788.14 AIM21091.1 - 1.1e-29 102.2 10.8 1.5e-29 101.8 10.8 1.2 1 0 0 1 1 1 1 LrgA family Wzy_C PF04932.15 AIM21091.1 - 7.4 6.2 7.6 1e+02 2.5 7.2 2.1 1 1 0 1 1 1 0 O-Antigen ligase MFS_1 PF07690.16 AIM21092.1 - 4.9e-29 101.4 41.0 4.9e-29 101.4 41.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 AIM21092.1 - 9.6e-08 31.0 25.5 9.6e-08 31.0 25.5 2.0 2 0 0 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.7 AIM21092.1 - 5e-07 28.9 30.4 1.5e-06 27.4 26.6 2.8 1 1 1 2 2 2 1 MFS_1 like family MFS_3 PF05977.13 AIM21092.1 - 0.0024 16.3 7.2 0.0024 16.3 7.2 2.4 3 0 0 3 3 3 1 Transmembrane secretion effector OATP PF03137.20 AIM21092.1 - 0.56 8.4 21.2 0.036 12.4 1.2 3.3 3 1 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family Peripla_BP_4 PF13407.6 AIM21093.1 - 9.8e-31 107.3 5.9 1.2e-30 106.9 5.9 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_3 PF13377.6 AIM21093.1 - 4e-08 33.8 0.0 1.1e-05 25.9 0.0 2.3 1 1 0 2 2 2 2 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 AIM21093.1 - 1.7e-07 30.9 0.1 2.5e-07 30.4 0.1 1.2 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Asparaginase_C PF17763.1 AIM21093.1 - 0.15 12.2 0.0 0.39 11.0 0.0 1.6 1 0 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain tRNA-synt_1g PF09334.11 AIM21094.1 - 4.1e-166 552.6 0.0 5.1e-166 552.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA_bind PF01588.20 AIM21094.1 - 1.1e-21 76.7 0.0 2.7e-21 75.5 0.0 1.7 2 0 0 2 2 2 1 Putative tRNA binding domain tRNA-synt_1 PF00133.22 AIM21094.1 - 2.2e-17 62.5 0.7 7.2e-12 44.4 0.1 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 AIM21094.1 - 2.9e-12 46.6 0.2 7.7e-05 22.2 0.0 2.4 2 1 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 AIM21094.1 - 2e-05 23.7 0.1 0.025 13.5 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (K) Anticodon_1 PF08264.13 AIM21094.1 - 2.9e-05 24.1 0.1 5.6e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA ParA PF10609.9 AIM21095.1 - 3e-99 331.5 0.0 3.6e-99 331.2 0.0 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 AIM21095.1 - 7e-12 45.5 0.0 2.2e-11 43.9 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 AIM21095.1 - 6.5e-10 39.2 0.2 1.4e-08 34.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 AIM21095.1 - 4.5e-08 32.7 0.0 7.3e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.18 AIM21095.1 - 5.5e-08 32.6 0.0 0.00058 19.4 0.0 2.3 2 1 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 AIM21095.1 - 0.00085 18.6 1.5 0.0013 18.0 0.2 1.8 2 1 0 2 2 2 1 Anion-transporting ATPase VirC1 PF07015.11 AIM21095.1 - 0.007 15.7 0.1 0.011 15.0 0.1 1.3 1 0 0 1 1 1 1 VirC1 protein CBP_BcsQ PF06564.12 AIM21095.1 - 0.019 14.5 0.2 0.099 12.1 0.2 2.1 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 AIM21095.1 - 0.043 13.4 0.2 0.081 12.5 0.2 1.4 1 0 0 1 1 1 0 AAA domain FeS_assembly_P PF01883.19 AIM21095.1 - 0.064 13.4 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Iron-sulfur cluster assembly protein MeaB PF03308.16 AIM21095.1 - 0.092 11.7 0.3 0.14 11.1 0.3 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CLP1_P PF16575.5 AIM21095.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_26 PF13500.6 AIM21095.1 - 0.18 11.6 0.9 20 4.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain PAP2 PF01569.21 AIM21096.1 - 1.6e-10 40.9 5.8 1.6e-10 40.9 5.8 2.4 2 1 1 3 3 3 1 PAP2 superfamily MASE2 PF05230.11 AIM21096.1 - 0.84 9.7 9.0 5.8 7.0 0.1 3.2 3 0 0 3 3 3 0 MASE2 domain PRK PF00485.18 AIM21097.1 - 1.1e-44 152.5 0.1 1.3e-44 152.3 0.1 1.0 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 AIM21097.1 - 4.3e-06 27.3 0.0 6.2e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain CoaE PF01121.20 AIM21097.1 - 0.0001 22.1 1.5 0.2 11.3 0.1 2.1 2 0 0 2 2 2 2 Dephospho-CoA kinase APS_kinase PF01583.20 AIM21097.1 - 0.00057 19.8 0.0 0.14 12.1 0.0 2.3 2 0 0 2 2 2 2 Adenylylsulphate kinase dNK PF01712.19 AIM21097.1 - 0.013 15.3 0.1 0.38 10.6 0.1 2.1 1 1 0 1 1 1 0 Deoxynucleoside kinase ABC_tran PF00005.27 AIM21097.1 - 0.014 15.9 0.0 0.021 15.3 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_17 PF13207.6 AIM21097.1 - 0.071 13.5 0.1 0.69 10.3 0.1 2.2 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 AIM21097.1 - 0.082 12.3 0.1 0.51 9.7 0.0 2.0 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Guanylate_kin PF00625.21 AIM21097.1 - 0.096 12.4 0.1 1.2 8.8 0.0 2.1 2 0 0 2 2 2 0 Guanylate kinase Zeta_toxin PF06414.12 AIM21097.1 - 0.12 11.6 0.0 0.39 10.0 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_16 PF13191.6 AIM21097.1 - 0.13 12.6 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 AIM21097.1 - 0.15 12.2 0.0 0.54 10.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain DCD PF06559.11 AIM21098.1 - 9.7e-11 41.0 0.0 3.7e-07 29.3 0.0 2.0 1 1 1 2 2 2 2 2'-deoxycytidine 5'-triphosphate deaminase (DCD) dUTPase PF00692.19 AIM21098.1 - 1e-08 34.9 0.0 1.3e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 dUTPase AsmA PF05170.14 AIM21099.1 - 4.2e-43 148.1 16.3 1.2e-21 77.2 11.8 2.1 1 1 1 2 2 2 2 AsmA family AsmA_2 PF13502.6 AIM21099.1 - 1.3e-22 80.4 13.9 2.3e-21 76.4 3.7 2.9 3 0 0 3 3 3 2 AsmA-like C-terminal region DUF2986 PF11661.8 AIM21100.1 - 0.057 14.0 0.7 0.057 14.0 0.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) DcuC PF03606.15 AIM21101.1 - 1.5e-125 419.3 41.5 1.7e-125 419.1 41.5 1.0 1 0 0 1 1 1 1 C4-dicarboxylate anaerobic carrier DctM PF06808.12 AIM21101.1 - 3.4e-09 36.0 42.5 3.4e-09 36.0 42.5 1.6 1 1 1 2 2 2 1 Tripartite ATP-independent periplasmic transporter, DctM component Na_H_antiporter PF03553.14 AIM21101.1 - 1.8e-05 24.1 14.7 1.8e-05 24.1 14.7 2.2 2 0 0 2 2 2 1 Na+/H+ antiporter family CitMHS PF03600.16 AIM21101.1 - 0.00098 18.4 27.1 0.00098 18.4 27.1 2.2 1 1 1 2 2 2 1 Citrate transporter TerC PF03741.16 AIM21102.1 - 5.8e-50 169.5 11.8 8.6e-50 168.9 11.8 1.3 1 0 0 1 1 1 1 Integral membrane protein TerC family CorC_HlyC PF03471.17 AIM21102.1 - 1.7e-20 72.8 0.0 1.5e-18 66.6 0.0 2.6 1 1 1 2 2 2 1 Transporter associated domain CBS PF00571.28 AIM21102.1 - 7.1e-13 48.8 0.1 2.8e-07 30.9 0.0 2.6 2 0 0 2 2 2 2 CBS domain S1-like PF14444.6 AIM21102.1 - 0.074 13.0 0.1 0.2 11.6 0.1 1.7 1 0 0 1 1 1 0 S1-like DUF475 PF04332.15 AIM21102.1 - 0.2 11.4 7.8 0.14 11.9 4.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF475) TssN PF17555.2 AIM21102.1 - 6.2 6.1 6.3 31 3.8 2.5 2.2 2 0 0 2 2 2 0 Type VI secretion system, TssN NTP_transferase PF00483.23 AIM21103.1 - 1.3e-26 93.7 0.0 1.7e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AIM21103.1 - 2.5e-07 31.2 0.1 6.5e-07 29.8 0.1 1.6 1 1 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 AIM21103.1 - 0.0072 16.1 0.1 0.015 15.0 0.0 1.6 2 0 0 2 2 2 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase PvlArgDC PF01862.16 AIM21103.1 - 0.028 14.2 0.0 0.064 13.1 0.0 1.6 1 1 0 1 1 1 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) NTP_transferase PF00483.23 AIM21104.1 - 5.2e-21 75.4 0.0 7e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AIM21104.1 - 9.8e-08 32.5 0.1 2.7e-05 24.6 0.0 2.2 1 1 1 2 2 2 2 MobA-like NTP transferase domain IspD PF01128.19 AIM21104.1 - 0.0075 16.0 0.2 0.017 14.9 0.0 1.7 2 0 0 2 2 2 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP_transf_3 PF02348.19 AIM21104.1 - 0.11 12.4 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 Cytidylyltransferase ZirS_C PF16583.5 AIM21104.1 - 0.19 11.3 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Zinc-regulated secreted antivirulence protein C-terminal domain Gly_reductase PF09338.11 AIM21104.1 - 0.2 10.0 0.0 0.32 9.3 0.0 1.2 1 0 0 1 1 1 0 Glycine/sarcosine/betaine reductase component B subunits Poly_export PF02563.16 AIM21105.1 - 3e-29 101.1 0.2 7.3e-28 96.6 0.1 2.7 3 0 0 3 3 3 1 Polysaccharide biosynthesis/export protein Wza_C PF18412.1 AIM21105.1 - 2.1e-16 59.3 0.9 5.3e-16 58.1 0.9 1.7 1 0 0 1 1 1 1 Outer-membrane lipoprotein Wza C-terminal domain SLBB PF10531.9 AIM21105.1 - 7.8e-16 57.7 0.1 8.5e-09 35.1 0.0 2.6 2 0 0 2 2 2 2 SLBB domain Adeno_PVIII PF01310.18 AIM21105.1 - 0.013 15.1 0.8 0.093 12.3 0.4 2.1 1 1 1 2 2 2 0 Adenovirus hexon associated protein, protein VIII Cupin_4 PF08007.12 AIM21105.1 - 0.059 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Cupin superfamily protein LMWPc PF01451.21 AIM21106.1 - 3e-41 141.1 0.0 3.3e-41 141.0 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase GNVR PF13807.6 AIM21107.1 - 4.3e-34 116.3 0.8 4.3e-34 116.3 0.8 2.1 2 0 0 2 2 2 1 G-rich domain on putative tyrosine kinase Wzz PF02706.15 AIM21107.1 - 5.1e-24 84.4 1.6 8.7e-24 83.6 0.0 2.2 2 0 0 2 2 2 1 Chain length determinant protein AAA_31 PF13614.6 AIM21107.1 - 1.4e-13 51.1 0.3 1.5e-12 47.7 0.0 2.7 3 0 0 3 3 3 1 AAA domain CbiA PF01656.23 AIM21107.1 - 5.5e-09 36.1 0.0 3.4e-08 33.6 0.0 2.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.6 AIM21107.1 - 5.7e-06 26.3 0.3 0.11 12.2 0.1 2.6 2 0 0 2 2 2 2 AAA domain ParA PF10609.9 AIM21107.1 - 6.5e-05 22.5 0.8 0.00025 20.6 0.8 1.9 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase DnaB_C PF03796.15 AIM21107.1 - 0.006 15.9 0.2 0.021 14.1 0.1 2.0 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain Fer4_NifH PF00142.18 AIM21107.1 - 0.0079 15.7 0.0 0.02 14.4 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 AIM21107.1 - 0.0084 15.6 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ Prefoldin_2 PF01920.20 AIM21107.1 - 0.012 15.5 3.5 0.038 13.9 1.0 2.9 3 0 0 3 3 3 0 Prefoldin subunit MipZ PF09140.11 AIM21107.1 - 0.017 14.4 0.0 0.052 12.8 0.0 1.7 1 1 0 1 1 1 0 ATPase MipZ AAA_25 PF13481.6 AIM21107.1 - 0.024 14.2 0.0 0.088 12.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain Glyco_transf_4 PF13439.6 AIM21108.1 - 2.1e-16 60.4 0.1 7.2e-16 58.6 0.1 1.9 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AIM21108.1 - 2.4e-15 57.4 0.0 8e-15 55.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 AIM21108.1 - 5.8e-11 43.0 0.0 1.1e-10 42.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AIM21108.1 - 9.4e-10 38.3 0.0 1.7e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 AIM21108.1 - 0.00013 22.0 0.1 0.00039 20.5 0.1 1.7 1 1 0 1 1 1 1 Glycosyl transferase 4-like Glyco_transf_5 PF08323.11 AIM21108.1 - 0.05 13.3 0.7 0.21 11.2 0.3 2.3 2 1 0 2 2 2 0 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 AIM21110.1 - 8.4e-33 113.3 0.0 1.9e-32 112.2 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AIM21110.1 - 5.9e-24 85.0 0.0 3.8e-22 79.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AIM21110.1 - 1.4e-09 38.2 0.0 3.2e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 AIM21110.1 - 7.3e-09 35.9 0.0 1.9e-08 34.5 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_20 PF00982.21 AIM21110.1 - 0.00078 18.2 0.0 0.0021 16.8 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase family 20 DUF2714 PF10896.8 AIM21110.1 - 0.054 13.5 0.1 0.21 11.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2714) Glycos_transf_1 PF00534.20 AIM21111.1 - 3.2e-24 85.4 0.0 5.2e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AIM21111.1 - 6.3e-18 65.5 0.0 1.4e-17 64.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AIM21111.1 - 1.7e-11 44.5 0.4 2.8e-11 43.7 0.4 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AIM21111.1 - 0.029 14.8 0.0 0.047 14.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain NTP_transferase PF00483.23 AIM21112.1 - 1.5e-74 250.7 0.0 5.3e-74 248.9 0.0 1.8 2 0 0 2 2 2 1 Nucleotidyl transferase MannoseP_isomer PF01050.18 AIM21112.1 - 8.8e-71 236.7 2.6 1.5e-70 235.9 2.6 1.4 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase Cupin_2 PF07883.11 AIM21112.1 - 3.3e-11 42.7 0.2 7.7e-11 41.6 0.2 1.7 1 0 0 1 1 1 1 Cupin domain NTP_transf_3 PF12804.7 AIM21112.1 - 1.1e-08 35.6 0.1 3.1e-08 34.1 0.0 1.8 2 0 0 2 2 2 1 MobA-like NTP transferase domain PGM_PMM_III PF02880.16 AIM21113.1 - 1.6e-24 86.3 0.0 2.4e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 AIM21113.1 - 2.2e-24 86.0 0.1 4.2e-24 85.1 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_I PF02878.16 AIM21113.1 - 4.7e-20 71.7 0.0 2.8e-19 69.2 0.0 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 AIM21113.1 - 4.2e-09 36.5 0.0 1e-08 35.2 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Bac_transf PF02397.16 AIM21114.1 - 1.2e-66 223.9 0.1 1.6e-66 223.4 0.1 1.2 1 0 0 1 1 1 1 Bacterial sugar transferase CoA_binding_3 PF13727.6 AIM21114.1 - 3.6e-31 108.5 0.2 7.2e-31 107.5 0.2 1.5 1 0 0 1 1 1 1 CoA-binding domain Glyco_tran_WecB PF03808.13 AIM21114.1 - 0.055 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Cellulase PF00150.18 AIM21115.1 - 1.6e-07 31.0 0.0 2.6e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_1 PF00232.18 AIM21115.1 - 0.0005 18.6 0.1 0.046 12.1 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 1 Glyco_hydro_10 PF00331.20 AIM21115.1 - 0.0064 15.7 0.0 0.096 11.8 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 10 Acyl_transf_3 PF01757.22 AIM21116.1 - 9.4e-26 90.7 42.5 1.1e-25 90.4 42.5 1.0 1 0 0 1 1 1 1 Acyltransferase family E1-E2_ATPase PF00122.20 AIM21116.1 - 4.9 6.6 7.1 9.7 5.7 3.5 2.9 2 1 0 2 2 2 0 E1-E2 ATPase DUF4214 PF13946.6 AIM21117.1 - 2.6e-19 69.0 0.0 0.00035 20.6 0.0 4.4 3 1 1 4 4 4 4 Domain of unknown function (DUF4214) ABC_tran PF00005.27 AIM21118.1 - 1.5e-28 100.0 0.0 2.7e-28 99.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 AIM21118.1 - 8.1e-13 48.6 10.8 1.2e-12 48.1 10.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.6 AIM21118.1 - 2.9e-06 27.3 0.0 0.063 13.1 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIM21118.1 - 0.00012 21.6 0.0 0.00039 19.9 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AIM21118.1 - 0.017 15.5 0.0 0.032 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 AIM21118.1 - 0.03 14.1 0.0 0.077 12.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 AIM21118.1 - 0.048 13.9 0.0 5.7 7.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 AIM21118.1 - 0.076 13.2 0.0 0.21 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 AIM21118.1 - 0.093 13.3 0.0 0.32 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain Ost5 PF05251.12 AIM21118.1 - 0.16 12.3 2.9 0.37 11.1 0.2 2.6 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit 5 HlyD PF00529.20 AIM21119.1 - 3.4e-20 71.7 0.7 9.6e-20 70.3 0.2 1.8 2 0 0 2 2 2 1 HlyD membrane-fusion protein of T1SS HlyD_3 PF13437.6 AIM21119.1 - 2.6e-19 69.9 3.2 4.3e-15 56.3 0.2 2.7 2 1 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AIM21119.1 - 1.4e-11 44.1 12.8 2.2e-09 37.0 2.7 3.3 3 0 0 3 3 2 2 Biotin-lipoyl like HlyD_D23 PF16576.5 AIM21119.1 - 4.4e-09 35.9 1.1 0.0011 18.2 0.0 2.3 2 0 0 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl PF00364.22 AIM21119.1 - 2.4e-06 27.3 6.4 1.9e-05 24.4 0.2 3.1 3 1 0 3 3 3 1 Biotin-requiring enzyme Lebercilin PF15619.6 AIM21119.1 - 3.5e-05 23.6 5.0 5.6e-05 22.9 5.0 1.3 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease Baculo_PEP_C PF04513.12 AIM21119.1 - 0.0022 18.1 1.7 0.012 15.7 0.0 2.5 2 1 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus TMCO5 PF14992.6 AIM21119.1 - 0.0025 17.4 1.9 0.0035 17.0 1.9 1.2 1 0 0 1 1 1 1 TMCO5 family Spc7 PF08317.11 AIM21119.1 - 0.0088 15.0 7.1 0.014 14.3 7.1 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Phage_Mu_Gam PF07352.12 AIM21119.1 - 0.024 14.6 1.2 0.024 14.6 1.2 1.8 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein Filament PF00038.21 AIM21119.1 - 0.069 12.7 10.4 0.037 13.6 7.6 1.9 2 1 0 2 2 2 0 Intermediate filament protein Fibin PF15819.5 AIM21119.1 - 0.1 12.4 1.4 0.17 11.6 1.4 1.3 1 0 0 1 1 1 0 Fin bud initiation factor homologue Syntaxin-6_N PF09177.11 AIM21119.1 - 0.11 13.1 2.1 0.11 13.0 0.5 1.9 2 0 0 2 2 1 0 Syntaxin 6, N-terminal AAA_13 PF13166.6 AIM21119.1 - 0.12 10.9 4.0 2.3 6.8 0.1 2.0 1 1 0 2 2 2 0 AAA domain Sec2p PF06428.11 AIM21119.1 - 0.26 11.3 7.2 1.1 9.3 0.5 2.8 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p Phage_GP20 PF06810.11 AIM21119.1 - 0.41 10.5 2.7 3.4 7.5 0.5 2.4 1 1 1 2 2 2 0 Phage minor structural protein GP20 EzrA PF06160.12 AIM21119.1 - 0.45 8.6 6.3 2.6 6.1 2.2 2.1 1 1 0 2 2 2 0 Septation ring formation regulator, EzrA YlqD PF11068.8 AIM21119.1 - 0.71 10.2 12.0 0.54 10.6 0.6 2.9 3 0 0 3 3 2 0 YlqD protein Fib_alpha PF08702.10 AIM21119.1 - 1 9.5 5.2 1.8 8.7 4.0 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 AIM21119.1 - 1 8.6 11.1 5 6.4 9.6 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4795 PF16043.5 AIM21119.1 - 1.2 8.7 7.9 27 4.3 7.7 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Occludin_ELL PF07303.13 AIM21119.1 - 1.3 9.8 5.6 1.2 9.9 1.7 2.2 2 0 0 2 2 2 0 Occludin homology domain Mod_r PF07200.13 AIM21119.1 - 1.5 8.9 9.6 19 5.3 9.6 2.2 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Cep57_MT_bd PF06657.13 AIM21119.1 - 2.9 8.4 6.8 19 5.8 0.5 2.9 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 THOC7 PF05615.13 AIM21119.1 - 3 8.1 7.7 18 5.6 0.1 2.4 1 1 1 2 2 2 0 Tho complex subunit 7 IMD PF08397.11 AIM21119.1 - 4.4 6.6 7.7 2.1 7.7 0.9 2.6 2 1 0 2 2 2 0 IRSp53/MIM homology domain Atg14 PF10186.9 AIM21119.1 - 5.3 6.0 10.6 92 2.0 10.6 2.0 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MscS_porin PF12795.7 AIM21119.1 - 6.4 6.3 20.7 0.6 9.6 15.5 1.9 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain TBCC_N PF16752.5 AIM21119.1 - 9.8 6.7 11.4 5.8 7.4 1.6 2.8 2 1 1 3 3 2 0 Tubulin-specific chaperone C N-terminal domain OEP PF02321.18 AIM21120.1 - 3.4e-58 196.6 26.9 1.8e-31 109.4 6.7 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein Sulfatase PF00884.23 AIM21120.1 - 0.044 13.2 0.9 0.068 12.5 0.0 1.7 2 0 0 2 2 2 0 Sulfatase AAA_31 PF13614.6 AIM21120.1 - 0.21 11.5 1.0 0.7 9.8 0.1 2.1 2 1 1 3 3 3 0 AAA domain GDP_Man_Dehyd PF16363.5 AIM21121.1 - 1.5e-60 205.4 0.0 1.7e-60 205.2 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 AIM21121.1 - 4.3e-60 203.2 0.0 5.2e-60 202.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 AIM21121.1 - 2.1e-19 69.6 0.0 2.8e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 AIM21121.1 - 8.6e-19 67.8 0.0 7.4e-18 64.7 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 AIM21121.1 - 1.3e-13 50.8 0.0 1.7e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 AIM21121.1 - 2.5e-09 37.3 0.0 3.9e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 AIM21121.1 - 1.3e-08 35.0 0.0 2e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 AIM21121.1 - 3.2e-08 33.3 0.1 1.3e-07 31.2 0.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 AIM21121.1 - 4.8e-08 32.9 0.1 3.1e-07 30.2 0.1 2.0 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.12 AIM21121.1 - 1.6e-07 30.8 0.0 7.6e-06 25.3 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein TrkA_N PF02254.18 AIM21121.1 - 0.004 17.4 0.1 0.009 16.3 0.1 1.5 1 1 0 1 1 1 1 TrkA-N domain adh_short_C2 PF13561.6 AIM21121.1 - 0.0052 16.4 0.0 0.0094 15.5 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.18 AIM21121.1 - 0.01 15.7 0.0 0.49 10.3 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 AIM21121.1 - 0.023 14.3 0.0 0.1 12.2 0.0 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NTP_transferase PF00483.23 AIM21122.1 - 7.3e-26 91.2 0.0 9.6e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AIM21122.1 - 3.1e-07 30.9 0.0 7.4e-07 29.7 0.0 1.5 1 1 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 AIM21122.1 - 0.0016 18.2 0.2 0.0092 15.7 0.0 1.9 2 0 0 2 2 2 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP_transf_3 PF02348.19 AIM21122.1 - 0.18 11.7 0.1 0.27 11.1 0.1 1.2 1 0 0 1 1 1 0 Cytidylyltransferase ABC2_membrane PF01061.24 AIM21123.1 - 1.2e-16 60.7 27.5 1.2e-16 60.7 27.5 1.4 1 1 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 AIM21124.1 - 2e-16 60.8 0.1 8.1e-16 58.8 0.1 1.9 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIM21124.1 - 5.3e-06 26.5 2.1 0.0042 17.0 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AIM21124.1 - 0.0021 17.7 0.1 0.0043 16.8 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 AIM21124.1 - 0.034 13.9 0.4 0.087 12.5 0.4 1.7 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 AIM21124.1 - 0.073 13.0 0.3 0.23 11.3 0.1 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 AIM21124.1 - 0.078 13.2 1.5 4 7.7 0.3 2.3 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 AIM21124.1 - 0.13 12.7 0.4 0.66 10.4 0.0 2.1 2 1 0 2 2 2 0 AAA domain SRP54 PF00448.22 AIM21124.1 - 0.15 11.6 0.3 0.77 9.3 0.1 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain SMC_N PF02463.19 AIM21124.1 - 0.2 11.1 0.7 2.9 7.3 0.1 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF4422 PF14393.6 AIM21125.1 - 1.2e-77 260.9 0.7 2.5e-77 259.8 0.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4422) Glyco_transf_8 PF01501.20 AIM21125.1 - 1.9e-45 155.4 0.4 3.4e-45 154.6 0.4 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 AIM21125.1 - 2.6e-06 27.0 0.4 4.9e-06 26.2 0.1 1.5 2 0 0 2 2 2 1 Glucosyltransferase 24 Mannosyl_trans3 PF11051.8 AIM21125.1 - 0.18 11.1 2.3 0.19 11.0 0.6 1.8 2 0 0 2 2 2 0 Mannosyltransferase putative GLF PF03275.13 AIM21126.1 - 1.3e-78 263.4 2.7 1.9e-78 262.8 2.7 1.3 1 0 0 1 1 1 1 UDP-galactopyranose mutase NAD_binding_8 PF13450.6 AIM21126.1 - 1.2e-17 63.9 0.1 3.6e-17 62.4 0.1 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 AIM21126.1 - 8.1e-05 22.7 0.0 0.00013 22.0 0.0 1.3 1 0 0 1 1 1 1 FAD-NAD(P)-binding ApbA PF02558.16 AIM21126.1 - 0.00013 21.7 0.1 0.00066 19.3 0.1 2.0 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 AIM21126.1 - 0.00028 20.2 0.0 0.00045 19.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AIM21126.1 - 0.00051 20.5 0.1 0.0014 19.1 0.0 1.7 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AIM21126.1 - 0.00071 18.9 0.1 0.0013 18.1 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 AIM21126.1 - 0.0021 17.7 0.4 0.0038 16.9 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 AIM21126.1 - 0.0077 15.8 0.1 0.013 15.1 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF1188 PF06690.11 AIM21126.1 - 0.0091 15.6 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1188) 3HCDH_N PF02737.18 AIM21126.1 - 0.016 15.1 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 AIM21126.1 - 0.045 13.8 0.1 0.077 13.1 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Amino_oxidase PF01593.24 AIM21126.1 - 0.057 12.7 0.0 0.071 12.4 0.0 1.1 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase K_oxygenase PF13434.6 AIM21126.1 - 0.059 12.5 0.0 0.084 12.0 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 AIM21126.1 - 0.06 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Epimerase PF01370.21 AIM21126.1 - 0.062 12.7 0.3 0.15 11.5 0.2 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 AIM21126.1 - 0.096 12.9 0.1 0.21 11.8 0.1 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 AIM21126.1 - 0.1 12.8 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 AIM21126.1 - 0.12 13.0 0.6 0.39 11.3 0.6 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Glycos_transf_2 PF00535.26 AIM21127.1 - 7.5e-14 51.9 0.0 1.2e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AIM21127.1 - 4.7e-09 36.5 0.0 6.3e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AIM21127.1 - 1.4e-05 25.6 0.1 2.3e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 AIM21127.1 - 2e-05 24.6 0.0 3.2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Transglut_core2 PF13369.6 AIM21127.1 - 0.0027 17.3 0.1 0.015 14.9 0.0 2.0 2 0 0 2 2 2 1 Transglutaminase-like superfamily Glyco_tranf_2_2 PF10111.9 AIM21127.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 BH4 PF02180.17 AIM21127.1 - 0.12 12.2 2.5 0.32 10.9 2.5 1.7 1 0 0 1 1 1 0 Bcl-2 homology region 4 Glycos_transf_1 PF00534.20 AIM21128.1 - 2.1e-25 89.3 0.0 3.5e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 AIM21128.1 - 1.6e-22 80.0 0.1 5.4e-22 78.3 0.1 1.8 2 0 0 2 2 2 1 Glycosyl transferase 4-like Glyco_trans_1_4 PF13692.6 AIM21128.1 - 2.4e-17 63.6 0.0 4.8e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AIM21128.1 - 3.2e-05 24.0 0.0 8.5e-05 22.6 0.0 1.7 1 1 1 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 AIM21128.1 - 0.00018 21.9 0.0 0.00048 20.5 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 6PGD PF00393.19 AIM21129.1 - 1.6e-133 444.6 0.2 2.1e-133 444.2 0.2 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 AIM21129.1 - 8.9e-52 175.4 0.0 1.6e-51 174.6 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 AIM21129.1 - 0.00059 20.4 0.0 0.002 18.7 0.0 2.0 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 AIM21129.1 - 0.0091 16.1 0.0 0.028 14.5 0.0 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 AIM21129.1 - 0.038 13.3 0.0 0.075 12.4 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 AIM21129.1 - 0.038 13.9 0.0 0.073 12.9 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.12 AIM21129.1 - 0.077 12.6 0.0 0.63 9.6 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_11 PF14833.6 AIM21129.1 - 0.12 12.6 0.1 0.41 10.9 0.1 1.9 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase ApbA PF02558.16 AIM21129.1 - 0.16 11.6 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Acyl_transf_3 PF01757.22 AIM21130.1 - 4.6e-15 55.5 39.6 1.4e-14 54.0 39.6 1.7 1 1 0 1 1 1 1 Acyltransferase family DUF4149 PF13664.6 AIM21130.1 - 0.025 14.9 3.1 0.025 14.9 3.1 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4149) Glycos_transf_2 PF00535.26 AIM21131.1 - 8.1e-30 103.9 0.1 9.1e-30 103.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 AIM21131.1 - 2.4e-11 43.7 0.1 2.8e-11 43.4 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 AIM21131.1 - 2.6e-11 43.9 0.0 2.9e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AIM21131.1 - 0.0001 22.7 0.0 0.00018 22.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 AIM21131.1 - 0.005 16.5 0.0 0.015 14.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase family 92 T4_baseplate PF12322.8 AIM21131.1 - 0.064 12.7 0.2 0.087 12.3 0.2 1.1 1 0 0 1 1 1 0 T4 bacteriophage base plate protein Glycos_transf_2 PF00535.26 AIM21133.1 - 1.8e-32 112.5 0.1 3.2e-32 111.7 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AIM21133.1 - 3.5e-16 59.8 0.0 6.4e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 AIM21133.1 - 7.2e-11 42.1 0.1 1.4e-10 41.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AIM21133.1 - 0.1 13.1 0.0 0.35 11.4 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 2 Glycos_transf_2 PF00535.26 AIM21134.1 - 2.9e-33 115.1 0.3 5.7e-33 114.1 0.3 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 AIM21134.1 - 4.2e-13 49.4 0.2 7e-13 48.7 0.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 AIM21134.1 - 3e-12 46.9 0.0 4.6e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AIM21134.1 - 0.00055 20.4 0.4 0.0039 17.7 0.1 2.7 3 1 0 3 3 3 1 Glycosyl transferase family 2 ZapB PF06005.12 AIM21134.1 - 0.0014 19.0 8.1 0.0032 17.9 4.7 3.0 3 0 0 3 3 3 1 Cell division protein ZapB Spc7 PF08317.11 AIM21134.1 - 0.0056 15.6 8.0 0.0087 15.0 8.0 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein ATG16 PF08614.11 AIM21134.1 - 0.065 13.4 12.3 0.13 12.4 12.3 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF641 PF04859.12 AIM21134.1 - 0.083 13.2 5.7 0.14 12.5 5.0 1.6 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) OmpH PF03938.14 AIM21134.1 - 0.39 11.0 6.0 0.78 10.1 4.9 2.0 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3450 PF11932.8 AIM21134.1 - 0.51 9.6 5.9 0.89 8.8 5.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) KxDL PF10241.9 AIM21134.1 - 1.2 9.5 5.3 1.7 9.0 1.7 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein DUF4472 PF14739.6 AIM21134.1 - 1.8 9.3 10.3 1.7 9.4 2.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) ABC_tran_CTD PF16326.5 AIM21134.1 - 2.4 8.5 10.1 7 7.0 10.1 1.8 1 0 0 1 1 1 0 ABC transporter C-terminal domain APG6_N PF17675.1 AIM21134.1 - 6 7.4 15.0 14 6.2 14.8 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region PRA-CH PF01502.18 AIM21135.1 - 3.6e-29 100.4 0.0 6e-29 99.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 AIM21135.1 - 3.4e-16 59.5 0.2 4.7e-16 59.0 0.2 1.2 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 AIM21135.1 - 0.029 14.5 0.2 0.045 13.9 0.2 1.3 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain His_biosynth PF00977.21 AIM21136.1 - 3.5e-78 262.2 0.5 3.9e-78 262.0 0.5 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Dus PF01207.17 AIM21136.1 - 4.2e-07 29.4 0.1 0.00032 19.9 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NMO PF03060.15 AIM21136.1 - 2.2e-05 24.0 0.2 0.014 14.8 0.0 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase ThiG PF05690.14 AIM21136.1 - 3.8e-05 23.1 0.2 0.0029 16.9 0.1 2.1 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG TMP-TENI PF02581.17 AIM21136.1 - 0.00083 18.7 0.0 0.087 12.2 0.0 2.3 2 0 0 2 2 2 1 Thiamine monophosphate synthase Oxidored_FMN PF00724.20 AIM21136.1 - 0.0036 16.6 0.0 0.046 13.0 0.0 2.1 2 0 0 2 2 2 1 NADH:flavin oxidoreductase / NADH oxidase family FMN_dh PF01070.18 AIM21136.1 - 0.0036 16.4 0.2 0.66 8.9 0.0 2.1 1 1 0 2 2 2 2 FMN-dependent dehydrogenase DHO_dh PF01180.21 AIM21136.1 - 0.004 16.4 0.0 0.12 11.6 0.0 2.1 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase G3P_antiterm PF04309.12 AIM21136.1 - 0.012 15.0 0.0 0.23 10.9 0.0 2.2 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator PcrB PF01884.17 AIM21136.1 - 0.12 11.8 0.0 0.39 10.1 0.0 1.8 2 1 1 3 3 3 0 PcrB family His_biosynth PF00977.21 AIM21137.1 - 9.1e-77 257.6 0.2 1e-76 257.4 0.2 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Trp_syntA PF00290.20 AIM21137.1 - 5.6e-07 28.7 0.4 3.4e-05 22.8 0.0 2.2 2 0 0 2 2 2 1 Tryptophan synthase alpha chain Dus PF01207.17 AIM21137.1 - 7.7e-07 28.5 0.3 0.00096 18.3 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) TMP-TENI PF02581.17 AIM21137.1 - 2.2e-05 23.9 1.4 0.026 13.9 0.1 2.8 2 1 1 3 3 3 2 Thiamine monophosphate synthase IGPS PF00218.21 AIM21137.1 - 9.5e-05 21.7 0.1 0.2 10.8 0.0 2.3 2 0 0 2 2 2 2 Indole-3-glycerol phosphate synthase NMO PF03060.15 AIM21137.1 - 0.00042 19.8 4.8 0.0013 18.2 0.6 2.1 2 0 0 2 2 2 1 Nitronate monooxygenase IMPDH PF00478.25 AIM21137.1 - 0.0023 17.0 1.6 0.035 13.1 0.1 2.1 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 AIM21137.1 - 0.0035 16.4 5.5 0.07 12.1 0.3 2.5 2 1 1 3 3 3 2 FMN-dependent dehydrogenase G3P_antiterm PF04309.12 AIM21137.1 - 0.0056 16.1 0.1 0.025 14.0 0.0 1.9 2 0 0 2 2 2 1 Glycerol-3-phosphate responsive antiterminator PEP_mutase PF13714.6 AIM21137.1 - 0.0076 15.7 0.0 0.034 13.6 0.0 1.9 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase ThiG PF05690.14 AIM21137.1 - 0.008 15.5 0.2 0.078 12.3 0.0 2.0 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG NanE PF04131.14 AIM21137.1 - 0.013 14.7 0.2 0.075 12.2 0.0 2.1 2 1 1 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase DHO_dh PF01180.21 AIM21137.1 - 0.017 14.4 0.2 0.038 13.2 0.0 1.6 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase Ribul_P_3_epim PF00834.19 AIM21137.1 - 0.02 14.3 0.3 0.47 9.8 0.0 2.3 2 0 0 2 2 2 0 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 AIM21137.1 - 0.05 13.4 0.0 0.51 10.1 0.0 2.0 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain GATase PF00117.28 AIM21138.1 - 7.3e-20 71.5 0.0 8.4e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 AIM21138.1 - 1.5e-08 34.7 0.0 7.2e-08 32.5 0.0 1.8 1 1 0 1 1 1 1 SNO glutamine amidotransferase family Peptidase_C26 PF07722.13 AIM21138.1 - 2.6e-06 27.4 0.2 0.0025 17.6 0.0 2.2 2 0 0 2 2 2 2 Peptidase C26 GATase_3 PF07685.14 AIM21138.1 - 0.00041 20.0 0.0 0.00057 19.5 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain IGPD PF00475.18 AIM21139.1 - 2.8e-65 219.0 0.3 3.9e-65 218.5 0.3 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase PNK3P PF08645.11 AIM21139.1 - 4.2e-07 29.8 0.0 0.0001 22.0 0.0 2.3 1 1 1 2 2 2 2 Polynucleotide kinase 3 phosphatase Hydrolase_like PF13242.6 AIM21139.1 - 2.3e-05 24.4 0.0 4.7e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 AIM21139.1 - 4.3e-05 23.7 0.0 0.0077 16.3 0.0 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase HAD PF12710.7 AIM21139.1 - 0.018 15.5 0.0 0.12 12.8 0.0 2.2 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Aminotran_1_2 PF00155.21 AIM21140.1 - 5.5e-62 210.0 0.0 6.6e-62 209.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 AIM21140.1 - 0.00012 21.1 0.0 0.0002 20.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 AIM21140.1 - 0.015 13.9 0.0 0.041 12.4 0.0 1.6 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Alliinase_C PF04864.13 AIM21140.1 - 0.042 12.7 0.0 0.079 11.8 0.0 1.4 1 0 0 1 1 1 0 Allinase Histidinol_dh PF00815.20 AIM21141.1 - 9e-163 542.0 2.2 1.1e-162 541.8 2.2 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase SIP PF04954.13 AIM21141.1 - 0.37 11.3 5.2 0.1 13.1 1.6 1.9 2 0 0 2 2 2 0 Siderophore-interacting protein FdhE PF04216.12 AIM21141.1 - 9 6.1 7.8 0.18 11.7 0.5 1.8 3 0 0 3 3 3 0 Protein involved in formate dehydrogenase formation HisG PF01634.18 AIM21142.1 - 5.7e-48 162.9 0.0 8.1e-48 162.4 0.0 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 AIM21142.1 - 1.1e-23 83.1 0.0 2.2e-23 82.2 0.0 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain Toprim_3 PF13362.6 AIM21142.1 - 0.13 12.7 0.0 4.2 7.8 0.0 2.3 2 0 0 2 2 2 0 Toprim domain Epimerase PF01370.21 AIM21143.1 - 6.6e-08 32.3 0.0 3.8e-07 29.8 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.15 AIM21143.1 - 8e-05 22.9 0.0 0.00011 22.4 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_10 PF13460.6 AIM21143.1 - 0.00072 19.5 0.0 0.00093 19.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 AIM21143.1 - 0.00077 19.0 0.0 0.024 14.0 0.0 2.7 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase UDPG_MGDP_dh_N PF03721.14 AIM21143.1 - 0.0046 16.5 0.0 0.0091 15.6 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 AIM21143.1 - 0.042 13.7 0.0 0.061 13.2 0.0 1.4 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.12 AIM21143.1 - 0.063 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 AIM21143.1 - 0.081 13.5 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 AIM21143.1 - 0.11 12.8 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain 3Beta_HSD PF01073.19 AIM21143.1 - 0.24 10.4 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family LysR_substrate PF03466.20 AIM21144.1 - 6e-23 81.3 2.6 9.3e-23 80.7 2.6 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM21144.1 - 8.9e-16 57.6 1.1 2.4e-15 56.2 1.1 1.8 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_5 PF01022.20 AIM21144.1 - 0.058 13.3 0.1 0.17 11.8 0.1 1.8 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Arginase PF00491.21 AIM21145.1 - 3.5e-89 299.0 0.0 4.3e-89 298.7 0.0 1.0 1 0 0 1 1 1 1 Arginase family SSF PF00474.17 AIM21146.1 - 1.1e-36 126.6 45.8 1.9e-36 125.9 45.8 1.4 1 1 0 1 1 1 1 Sodium:solute symporter family EptA_B_N PF08019.12 AIM21146.1 - 0.016 15.1 1.4 0.016 15.1 1.4 2.6 3 0 0 3 3 3 0 Phosphoethanolamine transferase EptA/EptB Transp_cyt_pur PF02133.15 AIM21147.1 - 2.8e-46 158.2 45.2 5e-46 157.4 45.2 1.4 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin CorA PF01544.18 AIM21148.1 - 6.7e-60 202.9 0.0 7.6e-60 202.7 0.0 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2207 PF09972.9 AIM21148.1 - 0.046 12.5 0.0 0.056 12.2 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3792 PF12670.7 AIM21148.1 - 0.06 13.5 0.0 0.093 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) Acetyltransf_1 PF00583.25 AIM21149.1 - 6e-11 42.6 0.0 7e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AIM21149.1 - 8.4e-10 39.0 0.0 1.2e-09 38.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AIM21149.1 - 5.4e-08 32.8 0.0 6.4e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AIM21149.1 - 0.00049 20.0 0.0 0.00081 19.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 AIM21149.1 - 0.0057 16.7 0.0 0.0089 16.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AIM21149.1 - 0.036 14.2 0.0 0.058 13.5 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase GSDH PF07995.11 AIM21150.1 - 6.9e-135 449.6 0.0 7.8e-135 449.4 0.0 1.0 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase GST_N_3 PF13417.6 AIM21151.1 - 8.3e-15 55.0 0.0 1.5e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 AIM21151.1 - 3e-12 46.7 0.0 6.8e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AIM21151.1 - 2.1e-10 40.7 0.0 4e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 AIM21151.1 - 3.3e-05 23.8 2.0 5.1e-05 23.2 0.1 2.1 1 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 AIM21151.1 - 0.00013 22.1 0.0 0.00021 21.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 AIM21151.1 - 0.00068 19.9 0.0 0.0011 19.2 0.0 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 AIM21151.1 - 0.0012 19.6 0.0 0.0026 18.5 0.0 1.5 1 1 1 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_3 PF14497.6 AIM21151.1 - 0.052 13.7 0.0 0.094 12.9 0.0 1.4 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain HAD PF12710.7 AIM21152.1 - 1.3e-39 136.6 0.1 1.5e-39 136.3 0.1 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AIM21152.1 - 0.013 15.8 0.2 0.083 13.2 0.2 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Terminase_5 PF06056.12 AIM21152.1 - 0.021 14.7 0.2 0.063 13.2 0.1 1.9 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) HTH_28 PF13518.6 AIM21152.1 - 0.061 13.5 0.1 0.44 10.7 0.0 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain Put_Phosphatase PF06888.12 AIM21152.1 - 0.084 12.3 0.0 0.099 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative Phosphatase DIOX_N PF14226.6 AIM21153.1 - 3.2e-36 124.6 0.0 5e-36 124.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 AIM21153.1 - 2.3e-18 66.5 0.0 3.6e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cys_Met_Meta_PP PF01053.20 AIM21154.1 - 2.3e-150 500.4 0.0 2.6e-150 500.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 AIM21154.1 - 2.8e-06 26.8 0.0 4.2e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 AIM21154.1 - 0.00041 19.8 0.0 0.00076 18.9 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 AIM21154.1 - 0.0048 15.9 0.0 0.007 15.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 AIM21154.1 - 0.19 11.0 0.0 0.37 10.0 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase PALP PF00291.25 AIM21155.1 - 1.1e-64 218.7 0.0 1.4e-64 218.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 AIM21155.1 - 2.9e-16 59.6 0.0 9.8e-06 25.9 0.1 3.6 3 0 0 3 3 3 3 CBS domain Peptidase_S11 PF00768.20 AIM21156.1 - 1e-96 323.1 0.0 1.3e-96 322.7 0.0 1.1 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase PBP5_C PF07943.13 AIM21156.1 - 7.4e-26 90.2 1.2 1.3e-25 89.5 1.2 1.4 1 0 0 1 1 1 1 Penicillin-binding protein 5, C-terminal domain Beta-lactamase2 PF13354.6 AIM21156.1 - 1.6e-11 44.2 0.0 2.2e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase enzyme family Beta-lactamase PF00144.24 AIM21156.1 - 0.015 14.6 0.0 0.48 9.6 0.0 2.2 2 0 0 2 2 2 0 Beta-lactamase Fimbrial PF00419.20 AIM21157.1 - 5.5e-14 52.7 0.0 7.4e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Fimbrial protein FimH_man-bind PF09160.10 AIM21158.1 - 1.5e-09 37.7 0.3 3.3e-09 36.6 0.1 1.7 2 0 0 2 2 2 1 FimH, mannose binding Fimbrial PF00419.20 AIM21158.1 - 8.4e-09 35.9 4.9 8.4e-09 35.9 4.9 1.8 2 0 0 2 2 2 1 Fimbrial protein SCPU PF05229.15 AIM21158.1 - 0.0049 17.3 0.5 0.014 15.8 0.5 1.8 1 0 0 1 1 1 1 Spore Coat Protein U domain Fimbrial PF00419.20 AIM21160.1 - 1.8e-17 64.0 3.5 2.2e-17 63.7 3.5 1.1 1 0 0 1 1 1 1 Fimbrial protein Fimbrial PF00419.20 AIM21161.1 - 6.2e-06 26.5 0.0 8.1e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Fimbrial protein Usher PF00577.20 AIM21162.1 - 3e-192 640.3 16.1 3.6e-192 640.1 16.1 1.1 1 0 0 1 1 1 1 Outer membrane usher protein PapC_N PF13954.6 AIM21162.1 - 5.4e-39 133.5 0.0 1.4e-38 132.2 0.0 1.8 1 0 0 1 1 1 1 PapC N-terminal domain PapC_C PF13953.6 AIM21162.1 - 2.7e-14 52.7 0.4 2.1e-13 49.8 0.0 2.6 2 0 0 2 2 2 1 PapC C-terminal domain Big_6 PF17936.1 AIM21162.1 - 0.033 14.4 0.3 0.093 13.0 0.3 1.7 1 0 0 1 1 1 0 Bacterial Ig domain PapD_N PF00345.20 AIM21163.1 - 5e-38 129.8 0.6 8.6e-38 129.1 0.6 1.4 1 0 0 1 1 1 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain PapD_C PF02753.17 AIM21163.1 - 2.1e-17 63.2 0.4 9.2e-17 61.2 0.2 2.2 2 0 0 2 2 2 1 Pili assembly chaperone PapD, C-terminal domain Fimbrial PF00419.20 AIM21165.1 - 2.6e-16 60.2 0.0 3.1e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 Fimbrial protein AIP3 PF03915.13 AIM21166.1 - 0.023 13.8 0.4 0.024 13.8 0.4 1.0 1 0 0 1 1 1 0 Actin interacting protein 3 TSNAXIP1_N PF15739.5 AIM21166.1 - 0.03 14.7 0.5 0.055 13.8 0.4 1.6 1 1 0 1 1 1 0 Translin-associated factor X-interacting N-terminus DUF3391 PF11871.8 AIM21166.1 - 0.068 13.7 1.5 0.12 12.9 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) FKBP_N PF01346.18 AIM21167.1 - 5.6e-12 46.5 0.0 5.6e-12 46.5 0.0 3.7 2 1 2 4 4 4 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase FKBP_C PF00254.28 AIM21167.1 - 9.6e-07 29.0 0.0 2e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Spc7 PF08317.11 AIM21167.1 - 2.9 6.7 16.1 0.26 10.1 8.5 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein USP8_interact PF08941.10 AIM21167.1 - 3.9 7.3 7.2 1.2 8.9 0.1 2.4 1 1 0 2 2 2 0 USP8 interacting GerE PF00196.19 AIM21168.1 - 6.9e-14 51.1 0.3 1e-13 50.6 0.3 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_5 PF01022.20 AIM21168.1 - 0.00025 20.9 0.0 0.0011 18.8 0.0 2.0 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family Sigma70_r4 PF04545.16 AIM21168.1 - 0.012 15.1 0.2 0.028 13.9 0.2 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_29 PF13551.6 AIM21168.1 - 0.019 15.0 0.1 0.045 13.8 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn helix Sigma70_r4_2 PF08281.12 AIM21168.1 - 0.02 14.6 0.1 0.038 13.7 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_38 PF13936.6 AIM21168.1 - 0.023 14.5 0.1 0.055 13.2 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 AIM21168.1 - 0.029 13.8 0.1 0.056 12.9 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.6 AIM21168.1 - 0.045 13.9 0.1 0.32 11.1 0.0 2.3 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.6 AIM21168.1 - 0.074 12.9 0.5 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 Homeodomain-like domain SDH_alpha PF03313.15 AIM21169.1 - 4e-94 315.1 6.4 4.9e-94 314.8 6.4 1.1 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 AIM21169.1 - 8.6e-56 188.6 0.1 1.6e-55 187.7 0.1 1.5 1 0 0 1 1 1 1 Serine dehydratase beta chain Trp_Tyr_perm PF03222.13 AIM21170.1 - 1.8e-11 43.7 31.7 3e-11 43.0 31.7 1.3 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family DUF3961 PF13106.6 AIM21170.1 - 0.059 13.0 0.0 0.059 13.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3961) ELK PF03789.13 AIM21170.1 - 0.072 13.2 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 ELK domain DeoRC PF00455.22 AIM21171.1 - 1.8e-47 161.2 0.0 3.9e-47 160.2 0.0 1.5 2 0 0 2 2 2 1 DeoR C terminal sensor domain HTH_DeoR PF08220.12 AIM21171.1 - 3.3e-11 42.7 0.0 5.4e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_23 PF13384.6 AIM21171.1 - 0.0016 18.1 0.5 0.0046 16.7 0.5 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_11 PF08279.12 AIM21171.1 - 0.0056 16.6 0.4 0.0093 15.9 0.4 1.4 1 0 0 1 1 1 1 HTH domain HTH_Mga PF08280.11 AIM21171.1 - 0.014 15.4 0.1 0.07 13.2 0.0 2.0 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain HTH_8 PF02954.19 AIM21171.1 - 0.035 13.9 0.2 0.071 12.9 0.2 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family Sigma70_r4 PF04545.16 AIM21171.1 - 0.091 12.3 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_17 PF12728.7 AIM21171.1 - 0.1 12.8 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain DeoC PF01791.9 AIM21172.1 - 2.5e-17 63.3 5.9 3e-17 63.0 5.9 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase DUF5318 PF17249.2 AIM21172.1 - 0.021 14.6 0.8 0.29 10.9 0.1 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5318) G3P_antiterm PF04309.12 AIM21172.1 - 0.92 8.9 4.1 0.68 9.3 0.2 2.4 3 0 0 3 3 3 0 Glycerol-3-phosphate responsive antiterminator PAP2 PF01569.21 AIM21174.1 - 3.7e-15 55.9 8.5 7.3e-15 54.9 8.5 1.6 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 AIM21174.1 - 1.5e-07 31.3 19.6 1.6e-06 28.0 19.6 2.2 1 1 0 1 1 1 1 PAP2 superfamily ResB PF05140.14 AIM21174.1 - 0.12 11.1 0.2 0.18 10.5 0.2 1.3 1 0 0 1 1 1 0 ResB-like family PAP2 PF01569.21 AIM21175.1 - 4.7e-09 36.1 8.6 4.7e-09 36.1 8.6 2.0 2 1 0 2 2 2 1 PAP2 superfamily Ecotin PF03974.13 AIM21176.1 - 6.9e-52 174.6 0.1 8.2e-52 174.3 0.1 1.1 1 0 0 1 1 1 1 Ecotin Ank_5 PF13857.6 AIM21177.1 - 6.9e-06 26.2 0.4 0.0012 19.1 0.1 3.3 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 AIM21177.1 - 1.6e-05 25.4 0.1 0.002 18.7 0.1 2.7 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 AIM21177.1 - 4.7e-05 23.9 0.0 0.0073 16.9 0.0 3.0 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 AIM21177.1 - 0.00049 20.4 0.2 9 6.9 0.0 4.4 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 AIM21177.1 - 0.0018 18.6 0.2 21 6.1 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 AIM21178.1 - 3.4e-05 24.4 0.1 0.002 18.7 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 AIM21178.1 - 0.00012 22.4 0.1 0.45 11.0 0.1 3.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 AIM21178.1 - 0.0005 20.3 0.3 2.9 8.8 0.2 4.3 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 AIM21178.1 - 0.0018 18.5 0.1 0.24 11.8 0.1 3.4 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 AIM21178.1 - 0.0024 18.4 0.1 1.4 9.6 0.0 3.4 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Phage_GPA PF05840.13 AIM21179.1 - 7.8e-48 163.2 2.2 1e-47 162.8 2.2 1.2 1 0 0 1 1 1 1 Bacteriophage replication gene A protein (GPA) MoCF_biosynth PF00994.24 AIM21179.1 - 0.0018 17.9 0.1 0.0033 17.1 0.1 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain YTH PF04146.15 AIM21182.1 - 0.096 12.6 0.1 0.14 12.1 0.1 1.1 1 0 0 1 1 1 0 YT521-B-like domain ATPase_2 PF01637.18 AIM21183.1 - 0.0033 17.4 0.7 0.0055 16.7 0.7 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Terminase_6C PF17289.2 AIM21184.1 - 2.7e-37 128.2 0.1 4.2e-37 127.6 0.1 1.3 1 0 0 1 1 1 1 Terminase RNaseH-like domain Terminase_6 PF03237.15 AIM21184.1 - 9.7e-15 54.8 0.0 2.5e-14 53.5 0.0 1.6 2 0 0 2 2 2 1 Terminase-like family SH3_16 PF18348.1 AIM21184.1 - 0.067 13.0 0.4 2.8 7.8 0.0 2.4 2 0 0 2 2 2 0 Bacterial dipeptidyl-peptidase Sh3 domain Ogr_Delta PF04606.12 AIM21186.1 - 5.7e-12 45.4 1.5 7.1e-12 45.1 1.5 1.2 1 0 0 1 1 1 1 Ogr/Delta-like zinc finger Asp-Al_Ex PF06826.12 AIM21187.1 - 2.3e-79 265.0 48.1 2.1e-41 141.5 23.4 2.1 2 0 0 2 2 2 2 Predicted Permease Membrane Region TrkA_C PF02080.21 AIM21187.1 - 1.5e-20 72.8 0.4 4.8e-09 35.9 0.0 2.5 2 0 0 2 2 2 2 TrkA-C domain YbjM PF11045.8 AIM21188.1 - 2.8e-42 143.6 8.1 3.2e-42 143.4 8.1 1.0 1 0 0 1 1 1 1 Putative inner membrane protein of Enterobacteriaceae Acyl_transf_3 PF01757.22 AIM21188.1 - 0.12 11.4 12.7 0.14 11.2 12.7 1.0 1 0 0 1 1 1 0 Acyltransferase family RseC_MucC PF04246.12 AIM21188.1 - 1.1 9.2 6.0 0.81 9.6 2.5 2.0 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Glutaredoxin PF00462.24 AIM21189.1 - 5.8e-16 58.5 0.0 7.3e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 AIM21189.1 - 1.4e-05 25.4 0.0 1.6e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.6 AIM21189.1 - 6.5e-05 22.9 0.0 0.00014 21.8 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin domain Thioredoxin_2 PF13098.6 AIM21189.1 - 0.00033 21.1 0.0 0.00052 20.4 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 AIM21189.1 - 0.022 14.6 0.0 0.025 14.4 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_4 PF13462.6 AIM21189.1 - 0.079 13.1 0.1 1.7 8.8 0.1 2.0 1 1 1 2 2 2 0 Thioredoxin DSBA PF01323.20 AIM21189.1 - 0.13 12.0 0.0 0.18 11.6 0.0 1.4 1 1 0 1 1 1 0 DSBA-like thioredoxin domain DUF1418 PF07214.12 AIM21190.1 - 2.1e-34 117.2 0.1 2.5e-34 117.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1418) TMEM51 PF15345.6 AIM21190.1 - 0.35 10.7 1.2 5.8 6.7 0.0 2.1 2 0 0 2 2 2 0 Transmembrane protein 51 RimK PF08443.11 AIM21191.1 - 3.5e-72 242.0 0.0 4.3e-72 241.7 0.0 1.1 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Rimk_N PF18030.1 AIM21191.1 - 5e-42 142.2 0.0 1e-41 141.2 0.0 1.5 1 0 0 1 1 1 1 RimK PreATP-grasp domain GSH-S_ATP PF02955.16 AIM21191.1 - 2.7e-18 66.0 0.4 4.2e-18 65.4 0.4 1.3 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATP-grasp_3 PF02655.14 AIM21191.1 - 4e-08 33.5 0.0 6.1e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 AIM21191.1 - 5e-07 29.3 0.0 0.0023 17.2 0.0 2.3 1 1 1 2 2 2 2 Sugar-transfer associated ATP-grasp Dala_Dala_lig_C PF07478.13 AIM21191.1 - 5e-05 22.9 0.1 0.00026 20.6 0.1 1.8 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_YheCD PF14398.6 AIM21191.1 - 0.011 15.0 0.1 0.074 12.3 0.1 2.4 1 1 1 2 2 2 0 YheC/D like ATP-grasp Arm-DNA-bind_3 PF13356.6 AIM21191.1 - 0.011 16.0 0.3 0.061 13.7 0.0 2.2 2 0 0 2 2 2 0 Arm DNA-binding domain ATPgrasp_Ter PF15632.6 AIM21191.1 - 0.012 15.4 0.1 0.031 14.0 0.1 1.6 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon R2K_3 PF14243.6 AIM21191.1 - 0.013 15.5 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 3 YbjN PF10722.9 AIM21192.1 - 1.9e-15 57.1 0.0 2.3e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 Putative bacterial sensory transduction regulator SBP_bac_8 PF13416.6 AIM21193.1 - 4.4e-38 131.7 4.8 5.3e-38 131.5 4.8 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AIM21193.1 - 1.7e-26 93.1 1.5 2.5e-26 92.6 1.5 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AIM21193.1 - 1.3e-19 71.3 7.9 1.8e-19 70.9 7.9 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 AIM21193.1 - 1.6e-08 34.6 0.1 2.2e-07 30.9 0.1 2.3 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein Lipoprotein_8 PF02030.15 AIM21193.1 - 5.6e-08 31.9 1.2 0.00016 20.6 0.0 2.6 2 1 0 3 3 3 2 Hypothetical lipoprotein (MG045 family) Sulphotransf PF09037.10 AIM21193.1 - 0.15 11.6 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Stf0 sulphotransferase ABC_tran PF00005.27 AIM21194.1 - 1.1e-39 136.0 0.0 1.7e-39 135.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter TOBE_2 PF08402.10 AIM21194.1 - 2e-19 69.5 0.0 6.6e-19 67.8 0.0 2.0 2 0 0 2 2 2 1 TOBE domain AAA_21 PF13304.6 AIM21194.1 - 8.3e-07 29.1 0.0 0.024 14.5 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 AIM21194.1 - 0.00018 21.4 0.0 0.00055 19.9 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 AIM21194.1 - 0.00068 20.1 0.0 0.0012 19.3 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 AIM21194.1 - 0.00092 18.7 0.1 0.013 15.0 0.1 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 AIM21194.1 - 0.0018 18.2 0.0 0.0036 17.2 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 AIM21194.1 - 0.0032 17.7 0.1 0.01 16.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AIM21194.1 - 0.0085 15.8 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.6 AIM21194.1 - 0.012 15.8 0.0 0.031 14.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 AIM21194.1 - 0.014 15.7 0.2 0.071 13.3 0.2 2.2 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AIM21194.1 - 0.042 14.4 0.0 0.063 13.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 AIM21194.1 - 0.053 13.9 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 AIM21194.1 - 0.097 12.7 0.0 0.26 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.25 AIM21194.1 - 0.099 12.3 0.0 0.17 11.5 0.0 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.29 AIM21194.1 - 0.1 13.1 0.0 0.77 10.2 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 AIM21194.1 - 0.15 12.0 0.0 0.36 10.7 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 AIM21194.1 - 0.17 11.4 0.9 0.56 9.7 0.0 2.1 2 1 0 2 2 2 0 AAA domain BPD_transp_1 PF00528.22 AIM21195.1 - 6.1e-23 81.5 17.4 6.1e-23 81.5 17.4 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 AIM21196.1 - 1.1e-13 51.4 21.0 1.1e-13 51.4 21.0 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component VSP PF03302.13 AIM21196.1 - 0.21 10.4 0.1 0.38 9.6 0.1 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF2593 PF10767.9 AIM21197.1 - 1e-59 200.7 3.2 1.2e-59 200.5 3.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2593) DUF998 PF06197.13 AIM21197.1 - 0.0054 16.3 5.5 0.0078 15.8 5.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF998) Tetraspanin PF00335.20 AIM21197.1 - 0.37 10.5 7.1 0.44 10.2 7.1 1.1 1 0 0 1 1 1 0 Tetraspanin family RhodobacterPufX PF11511.8 AIM21197.1 - 3.9 7.2 5.4 14 5.4 1.0 2.6 2 1 0 2 2 2 0 Intrinsic membrane protein PufX tRNA_U5-meth_tr PF05958.11 AIM21198.1 - 1.3e-17 63.9 0.0 2.8e-15 56.2 0.0 2.6 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 AIM21198.1 - 1.8e-07 31.0 0.0 4.2e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AIM21198.1 - 2.5e-06 27.2 0.0 4.7e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 AIM21198.1 - 3.4e-06 27.7 0.0 1.1e-05 26.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 AIM21198.1 - 0.0016 18.1 0.0 0.0031 17.1 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_11 PF08241.12 AIM21198.1 - 0.0021 18.6 0.0 0.005 17.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIM21198.1 - 0.0077 17.0 0.0 0.014 16.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 AIM21198.1 - 0.055 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 SBP_bac_3 PF00497.20 AIM21199.1 - 1.1e-70 237.5 0.7 1.3e-70 237.3 0.7 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 AIM21199.1 - 1.7e-06 28.2 0.0 7.2e-05 23.0 0.0 2.3 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site NMT1 PF09084.11 AIM21199.1 - 0.0064 16.5 0.2 0.021 14.8 0.1 1.8 1 1 1 2 2 2 1 NMT1/THI5 like NMT1_3 PF16868.5 AIM21199.1 - 0.013 14.9 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 NMT1-like family Phosphonate-bd PF12974.7 AIM21199.1 - 0.014 15.0 0.1 0.031 13.9 0.1 1.8 1 1 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein GHL15 PF14885.6 AIM21199.1 - 0.023 14.7 0.1 0.047 13.6 0.1 1.5 1 1 0 1 1 1 0 Hypothetical glycosyl hydrolase family 15 Spermine_synth PF01564.17 AIM21199.1 - 0.093 12.1 0.4 0.16 11.4 0.2 1.6 2 0 0 2 2 2 0 Spermine/spermidine synthase domain DUF4738 PF15889.5 AIM21199.1 - 0.67 9.8 3.5 1.3 8.8 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4738) BPD_transp_1 PF00528.22 AIM21200.1 - 1.4e-13 51.0 10.3 1.4e-13 51.0 10.3 1.9 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 AIM21201.1 - 7.1e-15 55.2 14.5 7.1e-15 55.2 13.9 1.3 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component MARVEL PF01284.23 AIM21201.1 - 0.0049 16.9 2.4 2.7 8.0 1.1 2.4 2 1 0 2 2 2 2 Membrane-associating domain SBP_bac_3 PF00497.20 AIM21202.1 - 5.9e-56 189.4 2.2 6.5e-56 189.3 2.2 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 AIM21202.1 - 0.00015 22.0 0.0 0.00027 21.1 0.0 1.4 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site NMT1 PF09084.11 AIM21202.1 - 0.011 15.7 0.2 0.056 13.4 0.2 2.0 2 1 0 2 2 2 0 NMT1/THI5 like Phosphonate-bd PF12974.7 AIM21202.1 - 0.023 14.3 0.3 0.17 11.4 0.3 1.9 1 1 1 2 2 2 0 ABC transporter, phosphonate, periplasmic substrate-binding protein YhfZ_C PF14503.6 AIM21202.1 - 0.03 13.9 0.1 0.031 13.8 0.1 1.3 1 0 0 1 1 1 0 YhfZ C-terminal domain ABC_tran PF00005.27 AIM21203.1 - 8.8e-36 123.4 0.0 1.2e-35 123.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIM21203.1 - 2.7e-12 47.1 0.3 7.8e-07 29.2 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIM21203.1 - 3.8e-06 26.5 0.0 0.00023 20.7 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 AIM21203.1 - 0.00019 21.3 0.0 0.2 11.3 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 AIM21203.1 - 0.00026 21.0 0.0 0.00044 20.2 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 AIM21203.1 - 0.0013 19.1 0.1 0.0023 18.3 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_13 PF13166.6 AIM21203.1 - 0.0032 16.2 0.0 0.067 11.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 AIM21203.1 - 0.0047 16.6 0.0 0.0082 15.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AIM21203.1 - 0.0087 16.6 0.0 0.014 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AIM21203.1 - 0.024 14.3 0.2 0.23 11.2 0.0 2.2 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.6 AIM21203.1 - 0.057 13.7 0.2 0.23 11.7 0.2 2.1 1 1 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 AIM21203.1 - 0.12 11.2 0.3 1.5 7.5 0.1 2.3 2 1 0 2 2 2 0 Predicted ATPase of the ABC class IstB_IS21 PF01695.17 AIM21203.1 - 0.13 12.0 0.1 1.2 8.8 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein Roc PF08477.13 AIM21203.1 - 0.19 11.9 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 AIM21203.1 - 0.23 11.0 1.2 0.84 9.2 1.2 2.0 1 1 0 1 1 1 0 AAA domain DUF3828 PF12883.7 AIM21204.1 - 1.3e-16 61.1 0.0 1.7e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3828) Endopep_inhib PF16800.5 AIM21204.1 - 0.15 12.0 0.0 0.19 11.6 0.0 1.1 1 0 0 1 1 1 0 IseA DL-endopeptidase inhibitor YbjQ_1 PF01906.17 AIM21205.1 - 1.4e-40 138.1 0.5 1.5e-40 138.0 0.5 1.0 1 0 0 1 1 1 1 Putative heavy-metal-binding DUF3300 PF11737.8 AIM21207.1 - 6.9e-62 209.0 6.2 9.4e-62 208.5 6.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3300) DUF5323 PF17257.2 AIM21207.1 - 2.6 8.0 6.1 1.8 8.5 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5323) Amidase_2 PF01510.25 AIM21208.1 - 2.8e-28 98.9 0.1 4e-28 98.4 0.1 1.2 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase HTH_Tnp_1 PF01527.20 AIM21208.1 - 0.14 12.5 0.0 0.49 10.8 0.0 2.0 1 1 0 1 1 1 0 Transposase MLTD_N PF06474.12 AIM21208.1 - 0.23 11.6 0.6 0.51 10.6 0.6 1.5 1 0 0 1 1 1 0 MltD lipid attachment motif Epimerase PF01370.21 AIM21209.1 - 8.8e-29 100.7 0.0 2.7e-28 99.0 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 AIM21209.1 - 1.7e-19 69.9 0.0 2.2e-19 69.6 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 AIM21209.1 - 3.6e-15 55.8 0.0 5e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 AIM21209.1 - 1.1e-11 44.9 0.0 1.6e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 AIM21209.1 - 1.7e-10 40.8 0.0 3.3e-10 39.9 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 AIM21209.1 - 1.3e-09 37.6 0.1 6.6e-09 35.3 0.0 1.9 1 1 1 2 2 2 1 Male sterility protein adh_short PF00106.25 AIM21209.1 - 7.1e-07 28.9 0.1 1.5e-06 27.8 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.13 AIM21209.1 - 0.0014 18.3 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short_C2 PF13561.6 AIM21209.1 - 0.0026 17.4 0.1 0.0055 16.3 0.1 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.26 AIM21209.1 - 0.033 14.2 0.0 0.061 13.3 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase KR PF08659.10 AIM21209.1 - 0.18 11.7 0.9 0.68 9.8 0.5 2.1 1 1 1 2 2 2 0 KR domain XPC-binding PF09280.11 AIM21209.1 - 2 8.2 7.3 1.9 8.3 0.3 3.2 3 0 0 3 3 3 0 XPC-binding domain DUF2867 PF11066.8 AIM21210.1 - 9.7e-15 55.2 0.1 1.7e-14 54.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2867) NAD_binding_10 PF13460.6 AIM21210.1 - 1.7e-14 54.1 0.0 2.7e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 AIM21210.1 - 4.9e-11 42.6 0.0 9.4e-11 41.6 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 AIM21210.1 - 2.1e-09 37.3 0.0 3e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 AIM21210.1 - 1.4e-05 24.2 0.0 2.3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 AIM21210.1 - 0.033 13.3 0.0 0.048 12.8 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 AIM21210.1 - 0.042 13.2 0.0 0.072 12.5 0.0 1.4 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 AIM21210.1 - 0.059 13.8 0.1 0.2 12.1 0.1 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.25 AIM21210.1 - 0.2 11.1 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase DUF1294 PF06961.13 AIM21211.1 - 1.1e-24 86.4 0.1 2.1e-24 85.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1294) DUF3094 PF11293.8 AIM21211.1 - 0.00055 19.6 0.2 0.00055 19.6 0.2 2.1 2 1 1 3 3 3 1 Protein of unknown function (DUF3094) DUF1129 PF06570.11 AIM21211.1 - 0.082 12.4 1.9 0.074 12.5 1.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) DUF4131 PF13567.6 AIM21211.1 - 0.66 9.6 14.0 0.92 9.1 3.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) PhoR PF11808.8 AIM21211.1 - 2.5 8.6 15.7 0.78 10.2 5.8 2.1 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR Beta_elim_lyase PF01212.21 AIM21212.1 - 3.4e-95 318.7 0.0 5.8e-95 317.9 0.0 1.3 1 1 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 AIM21212.1 - 0.00019 20.1 0.0 0.00021 19.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 AIM21212.1 - 0.007 15.7 0.1 0.055 12.8 0.0 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family TPP_enzyme_N PF02776.18 AIM21213.1 - 3e-42 144.1 0.3 1.4e-41 141.9 0.1 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 AIM21213.1 - 9.3e-40 135.9 2.2 1.3e-39 135.5 0.6 2.1 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 AIM21213.1 - 1.9e-34 118.3 0.0 3.9e-34 117.3 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Fer2 PF00111.27 AIM21214.1 - 9.4e-13 47.9 1.2 9.4e-13 47.9 1.2 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.21 AIM21214.1 - 1.6e-10 41.6 0.0 2.6e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 AIM21214.1 - 1.3e-07 31.9 0.0 4.3e-07 30.2 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 AIM21214.1 - 0.047 13.8 0.0 0.46 10.6 0.0 2.1 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Fer2_3 PF13085.6 AIM21214.1 - 0.1 12.6 0.6 0.19 11.7 0.6 1.4 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Prismane PF03063.20 AIM21215.1 - 4.6e-155 517.2 0.0 5.2e-155 517.0 0.0 1.0 1 0 0 1 1 1 1 Prismane/CO dehydrogenase family DUF3703 PF12487.8 AIM21215.1 - 0.0091 15.8 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3703) ALF PF03752.13 AIM21215.1 - 0.26 11.3 1.7 0.6 10.1 1.7 1.7 1 0 0 1 1 1 0 Short repeats of unknown function Lys_export PF03956.13 AIM21216.1 - 3.7e-59 199.5 22.5 4.3e-58 196.0 12.0 2.0 2 0 0 2 2 2 2 Lysine exporter LysO CoA_binding_3 PF13727.6 AIM21216.1 - 0.3 11.1 7.3 0.044 13.8 2.6 1.9 2 0 0 2 2 2 0 CoA-binding domain DUF2813 PF11398.8 AIM21217.1 - 1.6e-145 485.1 0.0 2.1e-145 484.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2813) AAA_15 PF13175.6 AIM21217.1 - 2.6e-12 47.1 0.0 3.6e-09 36.8 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 AIM21217.1 - 4e-08 32.9 0.0 8.2e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 AIM21217.1 - 4.5e-07 30.0 1.4 0.018 14.8 0.0 2.6 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AIM21217.1 - 0.00022 21.8 0.0 0.00032 21.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 AIM21217.1 - 0.0014 18.1 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_tran PF00005.27 AIM21217.1 - 0.0058 17.2 0.0 0.014 15.9 0.0 1.6 2 0 0 2 2 2 1 ABC transporter BDV_P24 PF06595.11 AIM21217.1 - 0.013 15.4 0.3 0.024 14.5 0.3 1.4 1 0 0 1 1 1 0 Borna disease virus P24 protein CHASE3 PF05227.13 AIM21217.1 - 0.17 11.8 3.3 7.8 6.4 2.6 2.3 2 0 0 2 2 2 0 CHASE3 domain DUF535 PF04393.13 AIM21218.1 - 1.6e-96 322.9 0.0 1.9e-96 322.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF535) HlyD_D23 PF16576.5 AIM21219.1 - 1.2e-19 70.4 11.5 1.1e-18 67.3 11.5 2.0 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AIM21219.1 - 1.8e-15 57.5 8.5 2.9e-13 50.4 0.5 2.5 2 0 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AIM21219.1 - 2e-09 37.1 15.9 1.3e-07 31.3 7.5 4.2 3 1 0 3 3 3 2 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AIM21219.1 - 1.2e-05 25.0 0.6 0.013 15.3 0.2 2.7 2 0 0 2 2 2 2 Biotin-requiring enzyme Peptidase_M23 PF01551.22 AIM21219.1 - 4.4e-05 23.6 0.6 0.15 12.3 0.1 2.6 2 0 0 2 2 2 2 Peptidase family M23 RnfC_N PF13375.6 AIM21219.1 - 0.017 15.1 2.2 0.3 11.1 0.3 3.2 3 0 0 3 3 3 0 RnfC Barrel sandwich hybrid domain DUF4131 PF13567.6 AIM21219.1 - 0.023 14.4 0.1 0.063 12.9 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) PTS_EIIA_1 PF00358.20 AIM21219.1 - 0.026 14.3 0.5 1.6 8.5 0.1 2.4 2 0 0 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 ERM PF00769.19 AIM21219.1 - 0.072 12.9 7.0 0.12 12.2 7.0 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family TOBE PF03459.17 AIM21219.1 - 1.6 9.1 8.0 0.88 9.9 0.2 4.2 5 1 0 5 5 5 0 TOBE domain Wzz PF02706.15 AIM21219.1 - 2.7 8.4 6.3 0.59 10.5 0.4 2.7 1 1 0 2 2 2 0 Chain length determinant protein MacB_PCD PF12704.7 AIM21220.1 - 9e-40 137.1 3.0 9e-40 137.1 3.0 1.8 2 0 0 2 2 1 1 MacB-like periplasmic core domain ABC_tran PF00005.27 AIM21220.1 - 1.1e-30 106.9 0.0 2.1e-30 106.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsX PF02687.21 AIM21220.1 - 1.6e-11 44.5 10.1 7.1e-11 42.4 2.0 3.3 3 0 0 3 3 3 1 FtsX-like permease family SMC_N PF02463.19 AIM21220.1 - 5.4e-05 22.7 0.1 0.036 13.5 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AIM21220.1 - 0.0005 19.8 0.2 0.0012 18.6 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 AIM21220.1 - 0.0019 18.1 0.4 0.84 9.4 0.2 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 AIM21220.1 - 0.0025 17.7 0.1 0.0074 16.2 0.1 1.8 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 AIM21220.1 - 0.0038 17.6 0.7 0.012 16.0 0.7 1.9 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 AIM21220.1 - 0.033 14.3 0.1 0.11 12.6 0.1 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 AIM21220.1 - 0.047 14.0 0.1 0.26 11.6 0.1 2.1 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 AIM21220.1 - 0.049 13.0 0.4 0.5 9.7 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.6 AIM21220.1 - 0.072 13.6 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 AIM21220.1 - 0.095 12.8 0.5 0.19 11.8 0.5 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_28 PF13521.6 AIM21220.1 - 0.095 12.9 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF4064 PF13273.6 AIM21220.1 - 0.22 11.8 13.5 0.23 11.7 6.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) AAA_30 PF13604.6 AIM21220.1 - 0.29 10.8 5.5 0.48 10.1 0.7 3.0 2 1 0 2 2 2 0 AAA domain DUF4396 PF14342.6 AIM21220.1 - 6.3 7.2 10.0 0.19 12.1 0.4 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4396) GPDPase_memb PF10110.9 AIM21220.1 - 9 5.0 7.3 4.8 5.9 0.2 2.3 2 1 0 2 2 2 0 Membrane domain of glycerophosphoryl diester phosphodiesterase CSD PF00313.22 AIM21221.1 - 3.4e-28 97.3 0.1 3.7e-28 97.2 0.1 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 AIM21221.1 - 0.018 14.7 0.1 0.023 14.4 0.1 1.2 1 0 0 1 1 1 0 Ribonuclease B OB domain S1 PF00575.23 AIM21221.1 - 0.18 12.1 0.0 0.21 12.0 0.0 1.2 1 0 0 1 1 1 0 S1 RNA binding domain ClpS PF02617.17 AIM21222.1 - 2.9e-33 113.5 0.1 3.5e-33 113.2 0.1 1.1 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS ExbD PF02472.16 AIM21222.1 - 0.069 13.3 0.0 0.086 13.0 0.0 1.2 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR Lipoprotein_16 PF03923.13 AIM21222.1 - 0.11 12.1 0.1 0.15 11.7 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized lipoprotein AAA_2 PF07724.14 AIM21223.1 - 5.2e-54 182.9 0.0 9e-50 169.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 AIM21223.1 - 6.5e-30 103.1 1.6 2e-29 101.5 1.6 1.9 1 0 0 1 1 1 1 AAA lid domain AAA PF00004.29 AIM21223.1 - 1.2e-24 87.3 0.1 5.4e-13 49.5 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 AIM21223.1 - 1.9e-24 85.5 0.2 8.1e-24 83.5 0.0 2.2 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 AIM21223.1 - 6.4e-18 65.1 0.0 4.2e-12 46.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 AIM21223.1 - 2.7e-16 59.4 2.9 4.8e-15 55.4 2.2 2.8 2 0 0 2 2 2 1 Clp amino terminal domain, pathogenicity island component Sigma54_activat PF00158.26 AIM21223.1 - 3.8e-12 46.2 0.1 7.2e-05 22.6 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_16 PF13191.6 AIM21223.1 - 1.1e-11 45.4 7.8 1.2e-06 29.0 0.5 4.4 4 1 0 4 4 4 2 AAA ATPase domain TniB PF05621.11 AIM21223.1 - 1.3e-11 44.3 0.1 1.8e-08 34.1 0.0 3.6 2 2 1 3 3 3 1 Bacterial TniB protein AAA_22 PF13401.6 AIM21223.1 - 4.2e-08 33.6 2.4 0.0064 16.8 0.1 4.3 2 2 1 3 3 3 2 AAA domain ResIII PF04851.15 AIM21223.1 - 3.4e-07 30.4 0.0 0.011 15.7 0.0 3.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit RuvB_N PF05496.12 AIM21223.1 - 1.1e-06 28.5 0.4 0.21 11.3 0.0 4.2 4 0 0 4 4 4 2 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 AIM21223.1 - 4.5e-06 26.3 0.0 0.098 12.2 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_14 PF13173.6 AIM21223.1 - 1.1e-05 25.5 0.0 0.015 15.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.11 AIM21223.1 - 6e-05 22.9 0.1 0.0012 18.8 0.1 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 AIM21223.1 - 6.7e-05 23.4 0.1 0.16 12.5 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 AIM21223.1 - 7.7e-05 22.3 0.3 0.23 11.0 0.0 2.9 3 0 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 AIM21223.1 - 0.00011 21.9 0.0 0.085 12.6 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein TIP49 PF06068.13 AIM21223.1 - 0.00039 19.8 0.0 0.46 9.6 0.0 2.7 2 0 0 2 2 2 2 TIP49 P-loop domain RsgA_GTPase PF03193.16 AIM21223.1 - 0.0014 18.6 0.0 2.1 8.3 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase Mg_chelatase PF01078.21 AIM21223.1 - 0.0015 18.0 1.5 13 5.1 0.0 4.3 3 2 1 5 5 5 0 Magnesium chelatase, subunit ChlI AAA_6 PF12774.7 AIM21223.1 - 0.002 17.1 0.0 0.0046 16.0 0.0 1.6 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region RNA_helicase PF00910.22 AIM21223.1 - 0.0034 17.8 0.0 3.1 8.2 0.0 2.8 2 0 0 2 2 2 1 RNA helicase TsaE PF02367.17 AIM21223.1 - 0.0039 17.2 0.0 1.6 8.7 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 AIM21223.1 - 0.0039 17.4 0.0 1.3 9.2 0.0 3.0 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 AIM21223.1 - 0.0081 15.5 1.1 4.9 6.4 0.0 3.7 4 0 0 4 4 4 1 Zeta toxin AAA_29 PF13555.6 AIM21223.1 - 0.016 14.9 0.0 3.1 7.6 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain CbiA PF01656.23 AIM21223.1 - 0.017 15.2 0.1 4.9 7.2 0.0 2.7 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.12 AIM21223.1 - 0.031 14.2 0.0 0.29 11.1 0.0 2.4 2 0 0 2 2 2 0 NACHT domain DEAD PF00270.29 AIM21223.1 - 0.033 14.0 0.2 10 5.9 0.0 3.2 3 1 0 3 3 3 0 DEAD/DEAH box helicase SRP54 PF00448.22 AIM21223.1 - 0.046 13.3 0.1 6.2 6.4 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_23 PF13476.6 AIM21223.1 - 0.066 13.7 3.1 2.8 8.4 0.6 3.5 2 1 0 2 2 2 0 AAA domain DNA_pol3_delta2 PF13177.6 AIM21223.1 - 0.07 12.9 0.1 3.6 7.3 0.0 3.5 4 0 0 4 4 4 0 DNA polymerase III, delta subunit eIF-1a PF01176.19 AIM21224.1 - 2.7e-27 94.3 0.0 3e-27 94.2 0.0 1.0 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 RsgA_N PF16745.5 AIM21224.1 - 3.8e-05 23.3 0.0 4.6e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 RsgA N-terminal domain RNase_II_C_S1 PF18614.1 AIM21224.1 - 0.013 15.5 0.0 0.033 14.1 0.0 1.9 1 1 0 1 1 1 0 RNase II-type exonuclease C-terminal S1 domain S1 PF00575.23 AIM21224.1 - 0.02 15.2 0.1 0.024 15.0 0.1 1.2 1 0 0 1 1 1 0 S1 RNA binding domain Myosin_N PF02736.19 AIM21224.1 - 0.09 12.6 0.0 5.2 7.0 0.0 2.3 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain Leu_Phe_trans PF03588.14 AIM21225.1 - 7.7e-73 243.6 0.0 9e-73 243.3 0.0 1.0 1 0 0 1 1 1 1 Leucyl/phenylalanyl-tRNA protein transferase Acetyltransf_6 PF13480.7 AIM21225.1 - 0.0065 16.6 0.1 0.02 15.0 0.1 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ABC_tran PF00005.27 AIM21226.1 - 4.3e-32 111.5 0.1 1.1e-31 110.2 0.0 1.7 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 AIM21226.1 - 1.4e-09 38.0 0.2 1.4e-09 38.0 0.2 2.3 1 1 1 2 2 2 1 ABC transporter transmembrane region AAA_21 PF13304.6 AIM21226.1 - 1.2e-07 31.9 0.7 0.0027 17.6 0.3 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AIM21226.1 - 3.9e-06 27.3 1.5 1.2e-05 25.7 1.5 1.9 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 AIM21226.1 - 9e-06 25.3 0.0 0.00023 20.7 0.0 2.1 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 AIM21226.1 - 0.00041 20.5 0.0 0.00073 19.7 0.0 1.3 1 0 0 1 1 1 1 Helicase HerA, central domain NACHT PF05729.12 AIM21226.1 - 0.0014 18.6 1.3 0.0083 16.1 0.3 2.2 2 0 0 2 2 2 1 NACHT domain T2SSE PF00437.20 AIM21226.1 - 0.0037 16.4 0.0 0.009 15.1 0.0 1.6 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.6 AIM21226.1 - 0.0043 16.7 0.1 0.011 15.4 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AIM21226.1 - 0.0043 16.8 0.1 0.0082 15.9 0.1 1.5 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 AIM21226.1 - 0.0053 16.8 0.0 0.0093 16.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 AIM21226.1 - 0.036 14.0 0.0 0.068 13.1 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 AIM21226.1 - 0.039 14.5 0.0 0.14 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 AIM21226.1 - 0.049 13.9 0.6 0.17 12.1 0.6 2.0 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AIM21226.1 - 0.054 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 AIM21226.1 - 0.12 12.7 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase MeaB PF03308.16 AIM21226.1 - 0.13 11.2 0.1 0.61 9.0 0.0 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB FtsK_SpoIIIE PF01580.18 AIM21226.1 - 0.14 11.5 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Fer4_NifH PF00142.18 AIM21226.1 - 0.18 11.2 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_23 PF13476.6 AIM21226.1 - 0.25 11.8 0.0 0.42 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain EI24 PF07264.11 AIM21226.1 - 1 9.6 20.3 1.6 9.0 6.0 2.5 2 0 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) ABC_membrane PF00664.23 AIM21227.1 - 4.8e-43 147.8 7.0 6.7e-43 147.3 7.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 AIM21227.1 - 3.6e-27 95.6 0.0 6.8e-27 94.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AIM21227.1 - 0.00016 21.2 0.0 0.013 14.9 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AIM21227.1 - 0.00068 19.5 3.3 0.15 11.8 0.0 2.8 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 AIM21227.1 - 0.00069 19.6 0.1 0.0019 18.1 0.1 1.7 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 AIM21227.1 - 0.0026 17.8 0.4 0.0076 16.3 0.2 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 AIM21227.1 - 0.0032 17.7 0.0 0.024 14.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AIM21227.1 - 0.011 16.1 1.6 0.036 14.5 1.6 1.9 1 1 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.23 AIM21227.1 - 0.057 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Dynamin family AAA_29 PF13555.6 AIM21227.1 - 0.12 12.1 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pyr_redox_2 PF07992.14 AIM21228.1 - 6e-48 163.6 0.5 7e-48 163.3 0.5 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AIM21228.1 - 1.7e-21 76.8 0.0 8e-18 64.7 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AIM21228.1 - 3.9e-16 59.4 1.1 3.9e-16 59.4 1.1 2.7 3 1 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AIM21228.1 - 2.1e-06 27.1 7.6 0.0085 15.2 0.2 4.0 2 1 1 4 4 4 2 FAD binding domain GIDA PF01134.22 AIM21228.1 - 2.1e-05 23.8 3.3 0.045 12.8 0.1 3.6 3 1 0 4 4 4 2 Glucose inhibited division protein A HI0933_like PF03486.14 AIM21228.1 - 2.3e-05 23.3 0.3 1.3 7.6 0.1 4.4 4 1 1 5 5 5 2 HI0933-like protein DAO PF01266.24 AIM21228.1 - 0.00037 20.2 0.2 2.1 7.8 0.1 3.5 4 0 0 4 4 4 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 AIM21228.1 - 0.00081 18.8 1.5 0.0011 18.3 0.0 1.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 AIM21228.1 - 0.0058 17.0 0.0 0.048 14.1 0.0 2.1 2 0 0 2 2 2 1 Putative NAD(P)-binding K_oxygenase PF13434.6 AIM21228.1 - 0.0071 15.5 0.0 0.033 13.3 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 AIM21228.1 - 0.022 13.2 0.0 0.025 13.0 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 AIM21228.1 - 0.022 15.0 0.1 0.17 12.2 0.0 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 AIM21228.1 - 0.022 14.1 0.6 3 7.1 0.1 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 AIM21228.1 - 0.05 12.9 0.8 0.71 9.1 0.1 2.5 2 1 1 3 3 3 0 Thi4 family Trp_halogenase PF04820.14 AIM21228.1 - 0.07 12.0 0.2 0.86 8.4 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Shikimate_DH PF01488.20 AIM21228.1 - 0.13 12.3 0.2 3.4 7.7 0.0 2.8 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase AsnC_trans_reg PF01037.21 AIM21229.1 - 6.7e-25 86.9 0.1 1.9e-24 85.4 0.0 1.7 2 0 0 2 2 2 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 AIM21229.1 - 2.3e-21 75.1 0.3 5e-21 74.0 0.2 1.6 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 AIM21229.1 - 5.3e-20 71.0 0.4 8.4e-20 70.3 0.4 1.3 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain MarR PF01047.22 AIM21229.1 - 0.0038 17.1 0.0 0.0073 16.2 0.0 1.4 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 AIM21229.1 - 0.027 14.4 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 MarR family Fe_dep_repress PF01325.19 AIM21229.1 - 0.067 13.4 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain LexA_DNA_bind PF01726.16 AIM21229.1 - 0.083 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 LexA DNA binding domain HTH_20 PF12840.7 AIM21229.1 - 0.085 12.9 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain E3_UFM1_ligase PF09743.9 AIM21229.1 - 0.089 12.4 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 E3 UFM1-protein ligase 1 FtsK_SpoIIIE PF01580.18 AIM21230.1 - 3.3e-72 242.8 0.0 5.4e-72 242.1 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family FtsK_4TM PF13491.6 AIM21230.1 - 6.1e-44 149.7 15.6 8.8e-44 149.2 15.6 1.2 1 0 0 1 1 1 1 4TM region of DNA translocase FtsK/SpoIIIE FtsK_gamma PF09397.10 AIM21230.1 - 2.5e-28 97.6 0.1 4.8e-28 96.8 0.1 1.5 1 0 0 1 1 1 1 Ftsk gamma domain FtsK_alpha PF17854.1 AIM21230.1 - 5.7e-28 97.0 0.0 1.3e-27 95.9 0.0 1.7 1 0 0 1 1 1 1 FtsK alpha domain AAA_10 PF12846.7 AIM21230.1 - 6.1e-05 22.1 0.0 0.0088 15.0 0.0 2.2 2 0 0 2 2 2 2 AAA-like domain DUF87 PF01935.17 AIM21230.1 - 0.00075 19.7 0.2 0.00075 19.7 0.2 2.2 2 0 0 2 2 2 1 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 AIM21230.1 - 0.018 14.0 0.0 0.34 9.8 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain T2SSE PF00437.20 AIM21230.1 - 0.018 14.1 0.0 0.037 13.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein LolA PF03548.15 AIM21231.1 - 7.7e-59 198.1 2.9 9e-59 197.9 2.9 1.0 1 0 0 1 1 1 1 Outer membrane lipoprotein carrier protein LolA DUF2092 PF09865.9 AIM21231.1 - 9.7e-06 25.1 0.1 0.001 18.5 0.0 2.2 2 0 0 2 2 2 2 Predicted periplasmic protein (DUF2092) MgsA_C PF12002.8 AIM21232.1 - 9.8e-66 220.8 0.9 1.7e-65 220.0 0.9 1.4 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 AIM21232.1 - 1.8e-22 79.5 0.0 4.3e-22 78.3 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 AIM21232.1 - 2.4e-15 57.1 0.0 4.8e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 AIM21232.1 - 4.2e-13 49.3 0.0 7.7e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 AIM21232.1 - 1.3e-06 28.0 0.2 0.0028 17.1 0.1 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 AIM21232.1 - 2.6e-06 27.5 0.4 9.1e-05 22.5 0.4 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AIM21232.1 - 2.8e-06 27.8 1.7 0.0053 17.2 0.0 3.3 1 1 1 3 3 3 2 AAA ATPase domain Sigma54_activat PF00158.26 AIM21232.1 - 1.1e-05 25.2 0.0 0.014 15.1 0.0 2.3 1 1 1 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 AIM21232.1 - 3.5e-05 24.1 0.6 0.076 13.3 0.1 2.6 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.6 AIM21232.1 - 0.00057 20.2 0.1 0.12 12.7 0.1 2.4 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 AIM21232.1 - 0.0019 18.0 0.0 0.0049 16.6 0.0 1.6 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 AIM21232.1 - 0.0021 18.1 0.0 0.0055 16.7 0.0 1.7 2 0 0 2 2 1 1 AAA domain ResIII PF04851.15 AIM21232.1 - 0.0021 18.1 0.4 0.32 11.0 0.1 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_3 PF07726.11 AIM21232.1 - 0.0024 17.7 0.0 0.012 15.5 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 AIM21232.1 - 0.003 17.3 0.1 0.17 11.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 AIM21232.1 - 0.004 17.3 0.0 0.0078 16.3 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_28 PF13521.6 AIM21232.1 - 0.0045 17.2 0.0 0.051 13.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 AIM21232.1 - 0.0097 15.7 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AIM21232.1 - 0.02 15.1 0.2 0.081 13.1 0.1 2.0 2 1 0 2 2 1 0 AAA domain AAA_2 PF07724.14 AIM21232.1 - 0.02 15.0 0.0 0.04 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 AIM21232.1 - 0.023 13.8 0.0 0.036 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DNA_pol3_delta2 PF13177.6 AIM21232.1 - 0.026 14.3 0.0 0.18 11.6 0.0 1.9 1 1 1 2 2 2 0 DNA polymerase III, delta subunit AAA_18 PF13238.6 AIM21232.1 - 0.027 15.0 0.0 0.053 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AIM21232.1 - 0.028 14.9 0.0 0.052 14.1 0.0 1.5 1 1 0 1 1 1 0 ABC transporter EIF_2_alpha PF07541.12 AIM21232.1 - 0.036 14.2 0.3 14 5.8 0.0 2.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 2 alpha subunit RNA_helicase PF00910.22 AIM21232.1 - 0.038 14.4 0.0 0.86 10.0 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_11 PF13086.6 AIM21232.1 - 0.081 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Resolvase PF00239.21 AIM21232.1 - 0.1 12.7 0.2 0.33 11.1 0.1 1.9 2 0 0 2 2 2 0 Resolvase, N terminal domain Parvo_NS1 PF01057.17 AIM21232.1 - 0.12 11.5 0.0 2.1 7.3 0.0 2.1 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 TniB PF05621.11 AIM21232.1 - 0.18 11.2 0.1 3.5 7.0 0.0 2.7 1 1 2 3 3 3 0 Bacterial TniB protein DUF2075 PF09848.9 AIM21232.1 - 0.67 9.1 1.7 6.3 5.9 0.2 2.4 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2075) tRNA-synt_2b PF00587.25 AIM21233.1 - 3.3e-36 124.9 0.0 4.9e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 AIM21233.1 - 3.7e-30 104.3 2.5 6.3e-30 103.6 2.5 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Phage_GP20 PF06810.11 AIM21233.1 - 0.053 13.3 0.6 0.088 12.6 0.6 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 NPV_P10 PF05531.12 AIM21233.1 - 0.099 13.1 0.0 0.25 11.8 0.0 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 AIM21233.1 - 0.12 11.2 2.2 0.21 10.5 2.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 AIM21233.1 - 0.23 11.5 4.0 1.5 8.8 2.5 2.5 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4140 PF13600.6 AIM21233.1 - 0.27 11.7 2.1 0.69 10.4 2.1 1.7 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF1801 PF08818.11 AIM21234.1 - 6.3e-12 45.8 0.0 8.3e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DU1801) MFS_1 PF07690.16 AIM21235.1 - 2.8e-35 121.9 53.1 3.4e-25 88.7 36.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 AIM21235.1 - 4.3e-15 55.9 33.7 6.4e-15 55.3 33.7 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 AIM21235.1 - 1.8e-07 30.4 28.2 5.7e-07 28.7 10.0 2.1 1 1 1 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 AIM21235.1 - 3e-06 26.4 13.7 3e-06 26.4 13.7 3.1 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.6 AIM21235.1 - 0.98 7.9 33.6 0.1 11.2 9.1 3.0 1 1 1 3 3 3 0 MFS/sugar transport protein Radical_SAM PF04055.21 AIM21236.1 - 1.4e-29 103.6 0.1 1.8e-29 103.2 0.1 1.1 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 AIM21236.1 - 4e-18 66.0 0.0 5.4e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AIM21236.1 - 8.7e-06 25.9 0.0 1.3e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain CCT PF06203.14 AIM21236.1 - 0.053 13.6 1.3 0.72 10.0 0.6 2.2 2 0 0 2 2 2 0 CCT motif PFL-like PF02901.15 AIM21237.1 - 2.9e-208 693.6 0.7 4.2e-208 693.1 0.7 1.2 1 0 0 1 1 1 1 Pyruvate formate lyase-like Gly_radical PF01228.21 AIM21237.1 - 2.4e-43 147.0 0.0 7e-43 145.5 0.0 1.9 2 0 0 2 2 2 1 Glycine radical Histone_HNS PF00816.21 AIM21237.1 - 0.16 12.8 0.5 0.36 11.7 0.5 1.6 1 0 0 1 1 1 0 H-NS histone family DUF2680 PF10925.8 AIM21237.1 - 0.23 11.5 1.5 0.43 10.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) Form_Nir_trans PF01226.17 AIM21238.1 - 2.4e-75 252.9 28.0 2.8e-75 252.7 28.0 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter YcaO PF02624.16 AIM21239.1 - 1.6e-81 274.1 0.0 2.7e-81 273.4 0.0 1.4 1 0 0 1 1 1 1 YcaO cyclodehydratase, ATP-ad Mg2+-binding YcaO_C PF18381.1 AIM21239.1 - 2.9e-66 222.6 0.2 4.4e-66 222.0 0.2 1.3 1 0 0 1 1 1 1 YcaO cyclodehydratase C-terminal domain Asparaginase PF00710.20 AIM21240.1 - 2.6e-63 213.0 1.2 2.7e-63 213.0 0.4 1.4 2 0 0 2 2 2 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 AIM21240.1 - 3.6e-26 91.6 0.3 7.4e-26 90.6 0.3 1.6 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain PC_rep PF01851.22 AIM21240.1 - 0.038 14.4 0.0 1.4 9.5 0.0 2.6 2 0 0 2 2 2 0 Proteasome/cyclosome repeat Aminotran_5 PF00266.19 AIM21241.1 - 9.9e-66 222.2 0.0 1.1e-65 222.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V EPSP_synthase PF00275.20 AIM21242.1 - 9.1e-153 508.8 0.0 1e-152 508.7 0.0 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) Cytidylate_kin PF02224.18 AIM21243.1 - 1.6e-82 276.4 0.0 1.8e-82 276.2 0.0 1.0 1 0 0 1 1 1 1 Cytidylate kinase Cytidylate_kin2 PF13189.6 AIM21243.1 - 8.7e-09 35.7 0.1 1.7e-08 34.8 0.1 1.5 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_18 PF13238.6 AIM21243.1 - 6.7e-06 26.7 0.0 1.8e-05 25.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 AIM21243.1 - 5.1e-05 23.7 0.6 0.0029 18.0 0.0 2.5 1 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 AIM21243.1 - 0.00087 19.5 0.1 0.0026 17.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 AIM21243.1 - 0.005 17.0 0.7 0.09 12.9 0.1 2.6 2 1 0 2 2 2 1 Shikimate kinase AAA_22 PF13401.6 AIM21243.1 - 0.0055 17.0 0.0 0.01 16.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 AIM21243.1 - 0.0093 16.5 0.0 0.015 15.8 0.0 1.6 1 1 0 1 1 1 1 ABC transporter ADK PF00406.22 AIM21243.1 - 0.0096 16.0 0.0 0.022 14.9 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase ATP_bind_2 PF03668.15 AIM21243.1 - 0.015 14.6 0.1 0.052 12.8 0.0 1.8 1 1 0 2 2 2 0 P-loop ATPase protein family dNK PF01712.19 AIM21243.1 - 0.021 14.7 0.1 0.061 13.2 0.0 1.8 2 1 1 3 3 3 0 Deoxynucleoside kinase AAA PF00004.29 AIM21243.1 - 0.035 14.5 0.0 0.074 13.5 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 AIM21243.1 - 0.045 13.8 0.0 0.097 12.7 0.0 1.4 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 AIM21243.1 - 0.056 13.8 1.3 0.16 12.4 1.3 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 AIM21243.1 - 0.12 12.6 0.4 0.37 11.0 0.4 2.1 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AIM21243.1 - 0.12 12.1 0.8 0.41 10.3 0.1 2.1 2 1 0 2 2 2 0 AAA domain S1 PF00575.23 AIM21244.1 - 3.9e-101 331.5 34.7 1e-21 77.0 0.7 6.1 6 0 0 6 6 6 6 S1 RNA binding domain PCB_OB PF17092.5 AIM21244.1 - 2.4e-11 44.4 12.3 0.0096 16.7 0.1 6.6 2 1 5 7 7 7 4 Penicillin-binding protein OB-like domain S1_2 PF13509.6 AIM21244.1 - 7.7e-05 22.7 9.7 7.3 6.7 0.2 6.5 5 3 0 5 5 5 3 S1 domain CsrA PF02599.16 AIM21244.1 - 0.0036 17.2 4.7 1.9 8.5 0.0 4.5 4 0 0 4 4 4 2 Global regulator protein family TOBE PF03459.17 AIM21244.1 - 0.1 12.9 4.5 8.4 6.8 0.8 3.6 3 1 0 3 3 3 0 TOBE domain BPL_C PF02237.17 AIM21244.1 - 0.45 10.5 13.8 28 4.7 0.4 6.8 7 0 0 7 7 7 0 Biotin protein ligase C terminal domain HupF_HypC PF01455.18 AIM21244.1 - 1.1 9.4 3.7 16 5.7 0.0 4.1 4 0 0 4 4 4 0 HupF/HypC family Bac_DNA_binding PF00216.21 AIM21245.1 - 2.9e-29 101.1 0.0 3.1e-29 101.0 0.0 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 AIM21245.1 - 9.3e-08 32.2 0.0 1.1e-07 32.0 0.0 1.1 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_bac_2 PF18175.1 AIM21245.1 - 0.00096 19.0 0.0 0.0013 18.6 0.0 1.2 1 0 0 1 1 1 1 CCDC81-like prokaryotic HU domain 2 HU-DNA_bdg PF14848.6 AIM21245.1 - 0.064 13.3 0.0 0.13 12.3 0.0 1.6 1 1 0 1 1 1 0 DNA-binding domain HU-CCDC81_euk_1 PF14908.6 AIM21245.1 - 0.071 13.3 0.0 0.085 13.0 0.0 1.1 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 1 MDMPI_C PF07398.11 AIM21245.1 - 0.13 13.1 0.0 0.27 12.1 0.0 1.5 1 1 1 2 2 2 0 MDMPI C-terminal domain Competence PF03772.16 AIM21246.1 - 1.8e-52 178.3 47.7 2.5e-52 177.8 47.7 1.2 1 0 0 1 1 1 1 Competence protein Lactamase_B PF00753.27 AIM21246.1 - 2.3e-16 60.4 0.2 3.6e-16 59.7 0.2 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF4131 PF13567.6 AIM21246.1 - 1.6e-08 34.4 0.0 1.6e-08 34.4 0.0 5.2 3 1 0 3 3 3 1 Domain of unknown function (DUF4131) Lactamase_B_2 PF12706.7 AIM21246.1 - 0.00014 21.4 0.2 0.00043 19.9 0.1 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain ABC_membrane PF00664.23 AIM21247.1 - 3.6e-58 197.4 19.4 4.8e-58 197.0 19.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 AIM21247.1 - 6.3e-36 123.9 0.4 2.3e-35 122.1 0.1 2.0 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 AIM21247.1 - 3.4e-09 36.5 3.2 3.4e-09 36.5 3.2 2.2 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 AIM21247.1 - 4.4e-06 26.7 0.1 1.8e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase DEAD PF00270.29 AIM21247.1 - 1e-05 25.3 0.5 5.5e-05 23.0 0.1 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_16 PF13191.6 AIM21247.1 - 3.5e-05 24.2 0.1 6.8e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AIM21247.1 - 0.00027 21.2 0.3 0.0031 17.8 0.3 2.4 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 AIM21247.1 - 0.0006 19.1 0.1 0.0025 17.1 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin Cytidylate_kin PF02224.18 AIM21247.1 - 0.0018 18.1 0.0 0.0035 17.1 0.0 1.5 1 0 0 1 1 1 1 Cytidylate kinase DUF2075 PF09848.9 AIM21247.1 - 0.0029 16.9 0.1 0.0045 16.3 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_15 PF13175.6 AIM21247.1 - 0.0034 17.1 0.0 0.0058 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.20 AIM21247.1 - 0.0042 17.0 0.0 0.0093 15.9 0.0 1.7 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_29 PF13555.6 AIM21247.1 - 0.0042 16.8 0.1 0.014 15.1 0.1 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 AIM21247.1 - 0.0054 16.8 0.2 0.017 15.2 0.2 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_30 PF13604.6 AIM21247.1 - 0.012 15.4 0.1 0.033 13.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AIM21247.1 - 0.013 15.2 0.0 0.031 14.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AIM21247.1 - 0.016 15.8 0.3 0.052 14.1 0.1 2.0 1 1 1 2 2 1 0 AAA domain DUF87 PF01935.17 AIM21247.1 - 0.016 15.3 1.0 0.061 13.4 0.2 2.3 2 1 0 2 2 2 0 Helicase HerA, central domain AAA_21 PF13304.6 AIM21247.1 - 0.023 14.5 0.3 3.1 7.5 0.1 2.2 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_membrane_2 PF06472.15 AIM21247.1 - 0.028 13.8 7.9 0.017 14.5 5.7 1.7 1 1 1 2 2 2 0 ABC transporter transmembrane region 2 G-alpha PF00503.20 AIM21247.1 - 0.031 13.4 0.0 0.055 12.6 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit SbcCD_C PF13558.6 AIM21247.1 - 0.048 13.9 0.9 4.1 7.7 0.3 3.1 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit T2SSE PF00437.20 AIM21247.1 - 0.057 12.5 1.5 0.097 11.7 0.0 2.1 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_5 PF07728.14 AIM21247.1 - 0.066 13.2 0.1 0.33 10.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 AIM21247.1 - 0.069 12.7 0.0 0.27 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 AIM21247.1 - 0.07 13.6 0.3 0.46 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 AIM21247.1 - 0.07 13.5 0.2 1.8 9.0 0.2 2.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) 6PF2K PF01591.18 AIM21247.1 - 0.077 12.3 0.1 0.23 10.7 0.0 1.8 2 0 0 2 2 2 0 6-phosphofructo-2-kinase AAA_7 PF12775.7 AIM21247.1 - 0.079 12.5 0.0 0.24 10.9 0.0 1.8 1 0 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 AIM21247.1 - 0.1 12.3 0.3 2.1 8.1 0.0 2.8 2 1 1 3 3 3 0 IstB-like ATP binding protein LpxK PF02606.14 AIM21248.1 - 1.2e-116 389.4 0.0 1.4e-116 389.2 0.0 1.0 1 0 0 1 1 1 1 Tetraacyldisaccharide-1-P 4'-kinase Glyco_transf_4 PF13439.6 AIM21248.1 - 0.00078 19.5 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 MobB PF03205.14 AIM21248.1 - 0.0013 18.7 0.0 0.0036 17.2 0.0 1.7 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_26 PF13500.6 AIM21248.1 - 0.11 12.4 0.2 0.49 10.2 0.0 2.1 2 1 0 2 2 2 0 AAA domain DUF1338 PF07063.13 AIM21249.1 - 5.2e-118 393.9 3.7 6.3e-118 393.7 3.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) CSD PF00313.22 AIM21250.1 - 1.8e-30 104.6 0.3 1.9e-30 104.5 0.3 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 AIM21250.1 - 0.0041 16.8 1.4 0.0052 16.4 1.4 1.4 1 1 0 1 1 1 1 Ribonuclease B OB domain CSD PF00313.22 AIM21251.1 - 3.3e-19 68.5 0.1 3.6e-19 68.4 0.1 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 AIM21251.1 - 0.013 15.2 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Ribonuclease B OB domain HTH_42 PF06224.12 AIM21252.1 - 6.9e-81 272.3 12.0 8.3e-81 272.1 12.0 1.1 1 0 0 1 1 1 1 Winged helix DNA-binding domain Trm112p PF03966.16 AIM21253.1 - 2.7e-10 40.7 0.2 4.6e-10 39.9 0.2 1.4 1 1 0 1 1 1 1 Trm112p-like protein TF_Zn_Ribbon PF08271.12 AIM21253.1 - 0.00092 18.7 0.2 0.0013 18.2 0.2 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding PADR1 PF08063.12 AIM21253.1 - 0.0088 15.8 0.3 0.011 15.5 0.3 1.2 1 0 0 1 1 1 1 PADR1 (NUC008) domain A2L_zn_ribbon PF08792.10 AIM21253.1 - 0.016 15.0 0.1 0.017 14.8 0.1 1.2 1 0 0 1 1 1 0 A2L zinc ribbon domain DUF2318 PF10080.9 AIM21253.1 - 0.022 14.9 0.0 0.024 14.7 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) zf-C3HC4_5 PF17121.5 AIM21253.1 - 0.042 13.7 0.2 0.065 13.1 0.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RRN7 PF11781.8 AIM21253.1 - 0.13 11.9 0.7 0.43 10.3 0.7 1.8 1 1 1 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 CTP_transf_3 PF02348.19 AIM21254.1 - 2.9e-69 233.4 0.0 3.4e-69 233.2 0.0 1.0 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 AIM21254.1 - 1.8e-13 51.2 0.7 2.5e-13 50.7 0.7 1.3 1 1 0 1 1 1 1 MobA-like NTP transferase domain APH PF01636.23 AIM21255.1 - 5.6e-07 29.7 2.4 7.5e-07 29.3 2.4 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 AIM21255.1 - 2.3e-05 23.8 0.0 8.1e-05 22.0 0.0 1.6 1 1 0 1 1 1 1 Fructosamine kinase DUF218 PF02698.17 AIM21256.1 - 2.4e-23 82.6 0.0 3.1e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 DUF218 domain DUF4131 PF13567.6 AIM21256.1 - 0.036 13.7 2.2 0.06 13.0 2.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Methyltransf_31 PF13847.6 AIM21257.1 - 4.3e-20 72.1 0.0 4.7e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AIM21257.1 - 2.1e-16 60.3 0.1 3.4e-16 59.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AIM21257.1 - 3.1e-16 59.7 0.1 6.1e-16 58.7 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AIM21257.1 - 5.6e-16 59.0 0.2 9.2e-16 58.3 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIM21257.1 - 2.3e-13 50.7 0.0 3.8e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AIM21257.1 - 6e-08 32.3 0.0 8.1e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 AIM21257.1 - 3.7e-06 27.0 0.0 3.7e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AIM21257.1 - 0.0001 21.9 0.1 0.00015 21.4 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.6 AIM21257.1 - 0.0008 20.4 0.1 0.0023 18.9 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain rRNA_methylase PF06962.12 AIM21257.1 - 0.0011 18.9 0.1 0.011 15.7 0.1 2.1 1 1 0 1 1 1 1 Putative rRNA methylase TehB PF03848.14 AIM21257.1 - 0.019 14.4 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_18 PF12847.7 AIM21257.1 - 0.021 14.8 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.10 AIM21257.1 - 0.03 13.9 0.0 0.048 13.2 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase SAM_MT PF04445.13 AIM21257.1 - 0.031 13.7 0.1 0.051 13.0 0.1 1.3 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase Methyltransf_20 PF12147.8 AIM21257.1 - 0.058 12.5 0.0 0.077 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase TPMT PF05724.11 AIM21257.1 - 0.076 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) DREV PF05219.12 AIM21257.1 - 0.099 11.7 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_9 PF08003.11 AIM21257.1 - 0.12 11.2 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) MukF_M PF17192.4 AIM21258.1 - 1.2e-84 281.9 4.1 1.2e-84 281.9 4.1 1.6 2 0 0 2 2 2 1 MukF middle domain MukF_C PF17193.4 AIM21258.1 - 3.3e-80 267.8 1.4 3.3e-80 267.8 1.4 1.7 2 0 0 2 2 2 1 MukF C-terminal domain KicB PF03882.14 AIM21258.1 - 3.4e-59 198.1 0.0 9.6e-59 196.6 0.0 1.8 1 0 0 1 1 1 1 MukF winged-helix domain VHL PF01847.16 AIM21258.1 - 0.12 12.3 0.1 0.32 10.9 0.0 1.7 2 0 0 2 2 2 0 VHL beta domain WXG100 PF06013.12 AIM21258.1 - 2.6 8.4 6.4 0.42 10.9 1.2 2.5 3 0 0 3 3 3 0 Proteins of 100 residues with WXG MukE PF04288.13 AIM21259.1 - 2.7e-126 419.1 0.6 3.1e-126 418.9 0.6 1.0 1 0 0 1 1 1 1 MukE-like family Tfb2 PF03849.14 AIM21259.1 - 0.0073 15.3 0.0 0.0092 15.0 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 MukB PF04310.12 AIM21260.1 - 8.2e-125 415.0 0.1 8.2e-125 415.0 0.1 3.0 4 0 0 4 4 4 1 MukB N-terminal MukB_hinge PF16330.5 AIM21260.1 - 2.8e-74 248.3 0.6 2.8e-74 248.3 0.6 3.7 3 0 0 3 3 3 1 MukB hinge domain SbcCD_C PF13558.6 AIM21260.1 - 2.3e-14 53.4 0.0 2.3e-14 53.4 0.0 3.0 4 0 0 4 4 4 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 AIM21260.1 - 4.5e-08 32.7 0.1 9.2e-08 31.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain KxDL PF10241.9 AIM21260.1 - 0.00014 22.1 0.4 0.00014 22.1 0.4 7.6 9 1 0 9 9 9 1 Uncharacterized conserved protein ABC_tran PF00005.27 AIM21260.1 - 0.31 11.6 0.1 0.31 11.6 0.1 5.9 5 3 0 5 5 5 0 ABC transporter AAA_15 PF13175.6 AIM21260.1 - 0.32 10.6 0.0 0.32 10.6 0.0 3.9 4 1 0 5 5 5 0 AAA ATPase domain SMC_N PF02463.19 AIM21260.1 - 0.63 9.4 8.2 3.7 6.9 0.0 3.1 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF1759 PF03564.15 AIM21260.1 - 8.2 6.4 17.6 0.66 9.9 1.7 4.5 3 1 0 4 4 4 0 Protein of unknown function (DUF1759) YkuD PF03734.14 AIM21261.1 - 5.8e-29 101.4 0.1 1e-28 100.6 0.1 1.4 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain PG_binding_1 PF01471.18 AIM21261.1 - 1.3e-07 31.7 1.6 9.9e-06 25.7 0.0 2.8 2 0 0 2 2 2 2 Putative peptidoglycan binding domain Peptidase_M15_2 PF05951.13 AIM21262.1 - 4.5e-61 205.0 0.0 5.4e-61 204.8 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF882) Peptidase_M15_3 PF08291.11 AIM21262.1 - 1.7e-12 47.4 0.0 2.4e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase M15 Lactamase_B PF00753.27 AIM21263.1 - 2.7e-32 112.4 0.1 3.1e-32 112.2 0.1 1.0 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AIM21263.1 - 1.1e-05 25.1 0.0 1.2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 AIM21263.1 - 0.0025 17.7 0.0 0.0034 17.3 0.0 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_5 PF14597.6 AIM21263.1 - 0.0046 16.5 0.0 0.077 12.5 0.0 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 AIM21263.1 - 0.059 12.8 0.0 0.088 12.2 0.0 1.2 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain HAGH_C PF16123.5 AIM21263.1 - 0.076 13.5 0.0 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 Hydroxyacylglutathione hydrolase C-terminus Aminotran_1_2 PF00155.21 AIM21264.1 - 2.9e-92 309.7 0.0 3.2e-92 309.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Porin_1 PF00267.21 AIM21265.1 - 2.6e-150 500.5 31.5 3e-150 500.4 31.5 1.0 1 0 0 1 1 1 1 Gram-negative porin Porin_4 PF13609.6 AIM21265.1 - 2.3e-24 86.7 37.4 3.1e-24 86.3 37.4 1.2 1 0 0 1 1 1 1 Gram-negative porin OMP_b-brl PF13505.6 AIM21265.1 - 0.059 13.5 45.7 1.6 8.9 26.0 3.2 1 1 1 2 2 2 0 Outer membrane protein beta-barrel domain tRNA-synt_2 PF00152.20 AIM21266.1 - 3.2e-83 279.4 0.0 3.8e-83 279.2 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 AIM21266.1 - 2e-12 46.9 0.2 2e-11 43.7 0.0 2.2 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 AIM21266.1 - 0.0016 17.9 0.1 1.2 8.6 0.0 2.5 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) NAPRTase PF04095.16 AIM21267.1 - 4.5e-81 272.0 0.0 6.5e-81 271.5 0.0 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 AIM21267.1 - 7.7e-35 120.0 0.0 2.3e-34 118.5 0.0 1.8 2 0 0 2 2 2 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain GGDEF PF00990.21 AIM21268.1 - 4.6e-38 130.5 0.3 1.3e-37 129.0 0.0 1.9 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain GGDEF_2 PF17853.1 AIM21268.1 - 0.035 14.4 0.0 0.18 12.1 0.0 2.1 2 0 0 2 2 2 0 GGDEF-like domain FIVAR PF07554.13 AIM21268.1 - 2 9.3 7.0 0.77 10.6 0.8 3.1 3 0 0 3 3 3 0 FIVAR domain DUF3458_C PF17432.2 AIM21269.1 - 6e-123 410.3 9.1 9.8e-123 409.6 9.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3458_C) ARM repeats Peptidase_M1 PF01433.20 AIM21269.1 - 3.3e-55 187.0 2.4 6e-55 186.2 2.4 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain DUF3458 PF11940.8 AIM21269.1 - 2.1e-36 124.2 0.3 2.9e-35 120.6 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3458) Ig-like fold Peptidase_M1_N PF17900.1 AIM21269.1 - 3.8e-13 50.0 0.0 7.7e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Ovate PF04844.13 AIM21269.1 - 0.014 15.4 0.0 0.04 13.9 0.0 1.7 1 0 0 1 1 1 0 Transcriptional repressor, ovate DUF2063 PF09836.9 AIM21269.1 - 0.12 12.7 0.2 2.7 8.3 0.0 3.1 3 0 0 3 3 3 0 Putative DNA-binding domain ABC_tran PF00005.27 AIM21270.1 - 2.8e-30 105.6 0.0 3.8e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIM21270.1 - 3e-06 27.3 0.3 0.0075 16.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AIM21270.1 - 5e-06 27.0 0.8 7.7e-06 26.4 0.8 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AIM21270.1 - 3.5e-05 24.1 0.0 8.7e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 AIM21270.1 - 0.00025 20.6 0.0 0.32 10.4 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 AIM21270.1 - 0.00032 20.6 0.1 0.00055 19.9 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_33 PF13671.6 AIM21270.1 - 0.0004 20.5 0.0 0.00077 19.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AIM21270.1 - 0.00047 19.9 0.4 0.0028 17.4 0.2 2.1 1 1 1 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 AIM21270.1 - 0.0019 18.3 0.0 0.0029 17.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 AIM21270.1 - 0.0037 17.5 0.0 0.28 11.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 AIM21270.1 - 0.0044 16.7 0.0 0.0096 15.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 AIM21270.1 - 0.0055 16.3 0.9 0.031 13.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain ABC_ATPase PF09818.9 AIM21270.1 - 0.015 14.2 0.1 0.92 8.2 0.0 2.6 2 1 0 2 2 2 0 Predicted ATPase of the ABC class NB-ARC PF00931.22 AIM21270.1 - 0.02 14.1 0.2 0.094 11.9 0.1 2.1 2 1 1 3 3 3 0 NB-ARC domain ATPase PF06745.13 AIM21270.1 - 0.039 13.3 0.0 1.9 7.8 0.0 2.1 2 0 0 2 2 2 0 KaiC NACHT PF05729.12 AIM21270.1 - 0.052 13.5 0.5 0.098 12.6 0.1 1.6 2 0 0 2 2 2 0 NACHT domain Rad17 PF03215.15 AIM21270.1 - 0.13 12.2 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain BPD_transp_1 PF00528.22 AIM21271.1 - 7.5e-28 97.5 11.3 7.5e-28 97.5 11.3 1.5 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Romo1 PF10247.9 AIM21271.1 - 0.0092 16.3 0.2 0.03 14.7 0.2 1.8 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Bac_luciferase PF00296.20 AIM21272.1 - 8.6e-66 222.5 6.9 1.1e-65 222.2 6.9 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase SBP_bac_3 PF00497.20 AIM21273.1 - 4.9e-12 45.8 0.0 5.5e-09 35.8 0.0 2.3 1 1 1 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 NMT1 PF09084.11 AIM21273.1 - 1.1e-11 45.0 0.0 3.5e-11 43.4 0.0 1.7 1 1 1 2 2 2 1 NMT1/THI5 like NMT1_2 PF13379.6 AIM21273.1 - 8.8e-09 35.4 0.0 4.4e-08 33.1 0.0 2.0 1 1 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.7 AIM21273.1 - 7.7e-08 32.2 0.0 1.1e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1_3 PF16868.5 AIM21273.1 - 7.6e-06 25.5 0.0 1.5e-05 24.6 0.0 1.4 2 0 0 2 2 2 1 NMT1-like family OpuAC PF04069.12 AIM21273.1 - 0.00019 21.1 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system FMN_red PF03358.15 AIM21274.1 - 2.3e-33 115.1 0.1 3.5e-33 114.5 0.1 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 AIM21274.1 - 3.8e-08 33.3 0.1 6.5e-08 32.5 0.0 1.5 2 0 0 2 2 2 1 Flavodoxin-like fold DHO_dh PF01180.21 AIM21275.1 - 4.4e-93 311.7 0.0 5.3e-93 311.5 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase OSCP PF00213.18 AIM21275.1 - 0.042 14.0 0.1 0.072 13.2 0.1 1.2 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit ZapC PF07126.12 AIM21276.1 - 7.6e-71 237.1 0.1 8.6e-71 236.9 0.1 1.0 1 0 0 1 1 1 1 Cell-division protein ZapC MOSC PF03473.17 AIM21277.1 - 4e-30 104.5 0.0 6.6e-30 103.8 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 AIM21277.1 - 7.6e-30 103.3 0.0 1.3e-29 102.5 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Fer2 PF00111.27 AIM21277.1 - 3.1e-13 49.5 1.2 5.5e-13 48.7 1.2 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 AIM21277.1 - 0.067 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 AIM21277.1 - 0.071 13.2 0.0 0.23 11.5 0.0 1.9 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain UPF0020 PF01170.18 AIM21278.1 - 1e-66 224.4 0.0 5.1e-62 209.1 0.0 2.3 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 Methyltrans_SAM PF10672.9 AIM21278.1 - 1.2e-19 70.6 0.1 2.2e-19 69.7 0.1 1.4 1 0 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase THUMP PF02926.17 AIM21278.1 - 3.6e-16 59.6 0.0 7.7e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 THUMP domain Cons_hypoth95 PF03602.15 AIM21278.1 - 3.7e-15 56.0 0.0 1.7e-10 40.8 0.0 3.6 2 1 1 3 3 3 2 Conserved hypothetical protein 95 Methyltransf_31 PF13847.6 AIM21278.1 - 6.6e-13 48.7 0.2 2.5e-05 24.1 0.0 4.2 3 1 1 4 4 4 2 Methyltransferase domain Methyltransf_25 PF13649.6 AIM21278.1 - 4e-11 43.5 0.0 2.7e-05 24.8 0.0 3.5 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.12 AIM21278.1 - 6.4e-09 36.3 0.0 0.00029 21.4 0.0 3.2 3 0 0 3 3 3 2 Methyltransferase domain MTS PF05175.14 AIM21278.1 - 1.9e-08 34.0 0.0 0.00044 19.8 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_15 PF09445.10 AIM21278.1 - 9.8e-07 28.5 0.0 0.019 14.6 0.0 2.6 3 0 0 3 3 3 2 RNA cap guanine-N2 methyltransferase Methyltransf_3 PF01596.17 AIM21278.1 - 0.0034 16.6 0.0 2.9 7.0 0.0 2.6 3 0 0 3 3 3 2 O-methyltransferase PrmA PF06325.13 AIM21278.1 - 0.0047 16.4 0.0 11 5.3 0.0 3.2 2 1 0 3 3 3 1 Ribosomal protein L11 methyltransferase (PrmA) N6_Mtase PF02384.16 AIM21278.1 - 0.011 15.0 0.0 0.081 12.2 0.0 2.3 2 1 0 2 2 2 0 N-6 DNA Methylase AviRa PF11599.8 AIM21278.1 - 0.1 12.0 0.0 50 3.3 0.0 3.6 3 1 0 3 3 3 0 RRNA methyltransferase AviRa ABC_tran PF00005.27 AIM21279.1 - 6e-48 162.9 0.1 6.5e-24 85.0 0.0 3.0 3 0 0 3 3 2 2 ABC transporter ABC_tran_CTD PF16326.5 AIM21279.1 - 2e-21 76.0 10.9 5.1e-21 74.7 10.9 1.8 1 0 0 1 1 1 1 ABC transporter C-terminal domain AAA_21 PF13304.6 AIM21279.1 - 3.2e-16 60.0 12.2 0.00038 20.4 0.2 4.5 2 2 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIM21279.1 - 3.2e-10 39.8 0.3 7.9e-05 22.2 0.0 4.1 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_tran_Xtn PF12848.7 AIM21279.1 - 4.2e-10 39.5 0.6 4.2e-10 39.5 0.6 2.7 2 1 1 3 3 1 1 ABC transporter AAA_16 PF13191.6 AIM21279.1 - 4.5e-09 36.9 3.6 4.3e-05 24.0 0.0 3.3 3 1 0 3 3 3 2 AAA ATPase domain AAA_15 PF13175.6 AIM21279.1 - 7.4e-09 35.8 0.9 0.00052 19.8 0.1 2.8 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 AIM21279.1 - 1.4e-08 35.1 1.2 0.00098 19.4 0.1 4.0 2 2 0 2 2 2 2 AAA domain AAA_23 PF13476.6 AIM21279.1 - 3.3e-08 34.3 6.1 0.036 14.6 0.0 3.6 4 0 0 4 4 3 2 AAA domain AAA_29 PF13555.6 AIM21279.1 - 1.1e-07 31.5 0.0 0.0056 16.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AIM21279.1 - 1.8e-06 27.9 0.0 0.09 12.7 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA PF00004.29 AIM21279.1 - 3.5e-06 27.5 0.0 0.0077 16.7 0.0 3.0 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 AIM21279.1 - 6.3e-06 26.2 0.0 0.16 12.0 0.0 2.9 3 0 0 3 3 2 2 50S ribosome-binding GTPase NACHT PF05729.12 AIM21279.1 - 8.2e-06 25.8 0.9 0.11 12.4 1.3 2.9 2 1 0 2 2 2 2 NACHT domain IstB_IS21 PF01695.17 AIM21279.1 - 1.2e-05 25.1 0.1 0.11 12.2 0.0 3.6 4 0 0 4 4 4 2 IstB-like ATP binding protein AAA_30 PF13604.6 AIM21279.1 - 2.2e-05 24.3 0.0 0.22 11.2 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.6 AIM21279.1 - 3e-05 24.2 0.0 0.21 11.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 AIM21279.1 - 3.9e-05 23.5 0.0 0.28 10.9 0.0 2.9 3 0 0 3 3 3 2 AAA domain TsaE PF02367.17 AIM21279.1 - 3.9e-05 23.6 0.0 0.084 12.9 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 AIM21279.1 - 4.9e-05 23.6 0.3 0.21 11.9 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 AIM21279.1 - 5.5e-05 22.8 0.0 0.13 11.8 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region RNA_helicase PF00910.22 AIM21279.1 - 5.6e-05 23.5 0.0 0.22 11.9 0.0 2.6 2 0 0 2 2 2 2 RNA helicase Zeta_toxin PF06414.12 AIM21279.1 - 6.2e-05 22.4 0.3 0.9 8.8 0.0 3.4 2 1 1 3 3 3 2 Zeta toxin AAA_18 PF13238.6 AIM21279.1 - 0.0001 22.9 0.0 0.86 10.2 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 AIM21279.1 - 0.00013 22.0 0.9 0.3 11.1 0.0 3.5 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 AIM21279.1 - 0.00015 21.4 0.8 0.63 9.6 0.0 3.5 4 0 0 4 4 3 2 AAA domain T2SSE PF00437.20 AIM21279.1 - 0.00017 20.7 0.0 0.033 13.3 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein MobB PF03205.14 AIM21279.1 - 0.0004 20.3 0.1 0.055 13.4 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.6 AIM21279.1 - 0.00063 19.8 0.0 0.25 11.4 0.0 3.0 4 0 0 4 4 2 1 AAA domain FeoB_N PF02421.18 AIM21279.1 - 0.00072 19.1 0.5 6 6.4 0.0 3.9 4 0 0 4 4 4 0 Ferrous iron transport protein B Rad17 PF03215.15 AIM21279.1 - 0.00076 19.4 0.0 0.5 10.3 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain DUF815 PF05673.13 AIM21279.1 - 0.00083 18.6 0.0 0.33 10.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ATPase_2 PF01637.18 AIM21279.1 - 0.00093 19.2 0.0 0.22 11.4 0.0 2.5 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea Roc PF08477.13 AIM21279.1 - 0.0013 18.9 0.1 1.1 9.5 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 AIM21279.1 - 0.0016 18.2 0.4 0.63 9.8 0.2 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 AIM21279.1 - 0.0023 17.9 3.6 0.48 10.3 0.0 3.3 3 0 0 3 3 3 1 NTPase NB-ARC PF00931.22 AIM21279.1 - 0.0027 16.9 0.1 0.91 8.6 0.1 2.4 2 0 0 2 2 2 1 NB-ARC domain cobW PF02492.19 AIM21279.1 - 0.0034 17.0 0.1 0.98 9.0 0.0 3.0 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain RuvB_N PF05496.12 AIM21279.1 - 0.0044 16.8 0.0 0.71 9.6 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain ATP-synt_ab PF00006.25 AIM21279.1 - 0.0061 16.2 0.0 0.94 9.1 0.1 2.2 1 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_13 PF13166.6 AIM21279.1 - 0.012 14.3 0.6 5.1 5.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 AIM21279.1 - 0.014 15.5 0.0 2.6 8.1 0.0 2.9 3 0 0 3 3 3 0 Dynamin family SRP54 PF00448.22 AIM21279.1 - 0.014 15.0 0.5 1.1 8.8 0.2 2.6 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain MeaB PF03308.16 AIM21279.1 - 0.016 14.2 0.0 1.8 7.5 0.0 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB dNK PF01712.19 AIM21279.1 - 0.016 15.1 0.0 3.5 7.4 0.0 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_10 PF12846.7 AIM21279.1 - 0.028 13.4 0.0 0.63 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain G-alpha PF00503.20 AIM21279.1 - 0.04 13.1 0.7 3.8 6.6 0.0 2.6 3 0 0 3 3 3 0 G-protein alpha subunit DUF87 PF01935.17 AIM21279.1 - 0.05 13.7 0.1 8.6 6.4 0.0 3.1 3 0 0 3 3 3 0 Helicase HerA, central domain Arf PF00025.21 AIM21279.1 - 0.057 12.9 0.2 11 5.4 0.0 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_19 PF13245.6 AIM21279.1 - 0.058 13.7 0.5 1 9.7 0.4 2.8 2 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 AIM21279.1 - 0.074 12.4 0.0 4.7 6.5 0.0 2.8 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI VirE PF05272.11 AIM21279.1 - 0.075 12.7 0.0 2.3 7.9 0.0 2.3 2 0 0 2 2 2 0 Virulence-associated protein E MCM PF00493.23 AIM21279.1 - 0.098 11.7 0.0 2 7.5 0.0 2.2 2 0 0 2 2 2 0 MCM P-loop domain DAP3 PF10236.9 AIM21279.1 - 0.1 11.8 0.3 15 4.6 0.0 2.8 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 Pox_A32 PF04665.12 AIM21279.1 - 0.13 11.7 0.0 10 5.5 0.0 2.7 3 0 0 3 3 2 0 Poxvirus A32 protein SRPRB PF09439.10 AIM21279.1 - 0.13 11.7 0.0 2.5 7.5 0.0 2.7 3 0 0 3 3 2 0 Signal recognition particle receptor beta subunit DLIC PF05783.11 AIM21279.1 - 0.17 10.7 0.1 1.6 7.4 0.0 2.0 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) FapA PF03961.13 AIM21279.1 - 0.19 10.3 0.8 1.2 7.7 0.1 2.2 2 1 1 3 3 3 0 Flagellar Assembly Protein A AAA_17 PF13207.6 AIM21279.1 - 0.6 10.5 3.7 34 4.9 0.3 3.9 3 1 0 3 3 2 0 AAA domain DUF3584 PF12128.8 AIM21279.1 - 2.9 5.3 23.0 0.46 7.9 5.3 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3584) PqiA PF04403.13 AIM21280.1 - 4.7e-94 312.4 31.1 6.6e-55 185.2 14.0 2.1 2 0 0 2 2 2 2 Paraquat-inducible protein A DZR PF12773.7 AIM21280.1 - 0.041 13.9 9.3 1.4 9.0 1.1 2.7 2 1 0 2 2 2 0 Double zinc ribbon zf-UDP PF14569.6 AIM21280.1 - 0.16 12.1 4.7 0.26 11.4 0.1 2.5 2 0 0 2 2 2 0 Zinc-binding RING-finger zinc_ribbon_4 PF13717.6 AIM21280.1 - 0.38 10.7 7.7 1.8 8.6 0.2 2.8 2 1 0 2 2 2 0 zinc-ribbon domain zf_UBZ PF18439.1 AIM21280.1 - 0.4 10.3 4.6 20 4.9 0.1 3.4 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Tmemb_55A PF09788.9 AIM21280.1 - 0.62 9.1 0.0 0.62 9.1 0.0 3.1 4 0 0 4 4 4 0 Transmembrane protein 55A Zn_Tnp_IS91 PF14319.6 AIM21280.1 - 1.6 8.8 5.1 4.7 7.3 0.1 2.3 2 0 0 2 2 2 0 Transposase zinc-binding domain UPF0547 PF10571.9 AIM21280.1 - 2 8.6 14.6 11 6.2 0.3 3.5 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 zf-FPG_IleRS PF06827.14 AIM21280.1 - 3 7.8 9.9 6.3 6.8 0.1 3.4 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS MlaD PF02470.20 AIM21281.1 - 5.9e-37 125.8 0.4 3.7e-13 49.6 0.0 3.4 3 0 0 3 3 3 3 MlaD protein DUF948 PF06103.11 AIM21281.1 - 0.0025 18.1 1.4 0.0078 16.4 0.6 2.2 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF948) APG17 PF04108.12 AIM21281.1 - 0.0049 16.0 0.8 0.009 15.2 0.8 1.3 1 0 0 1 1 1 1 Autophagy protein Apg17 MapZ_EC1 PF18041.1 AIM21281.1 - 0.067 13.4 0.6 0.15 12.3 0.6 1.5 1 0 0 1 1 1 0 MapZ extracellular domain 1 PilJ PF13675.6 AIM21281.1 - 0.072 13.1 0.8 0.15 12.1 0.8 1.5 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term DASH_Duo1 PF08651.10 AIM21281.1 - 0.08 12.7 3.6 0.07 12.9 1.4 2.1 2 1 0 2 2 2 0 DASH complex subunit Duo1 ArAE_1_C PF11728.8 AIM21281.1 - 0.36 10.8 4.6 0.75 9.8 4.6 1.4 1 0 0 1 1 1 0 Putative aromatic acid exporter C-terminal domain YlbD_coat PF14071.6 AIM21281.1 - 9.5 6.5 6.8 70 3.7 4.2 2.5 1 1 1 2 2 2 0 Putative coat protein ABC_trans_aux PF03886.13 AIM21282.1 - 1.1e-37 129.1 4.8 1.3e-37 128.9 4.8 1.0 1 0 0 1 1 1 1 ABC-type transport auxiliary lipoprotein component RMF PF04957.12 AIM21283.1 - 7.4e-30 102.9 4.3 8.7e-30 102.7 4.3 1.0 1 0 0 1 1 1 1 Ribosome modulation factor ketoacyl-synt PF00109.26 AIM21284.1 - 5.6e-55 186.7 3.5 5.6e-55 186.7 3.5 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 AIM21284.1 - 1.9e-33 115.0 2.4 4.2e-33 113.8 2.4 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 AIM21284.1 - 0.00052 19.5 0.5 0.0042 16.5 0.1 2.2 2 0 0 2 2 2 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 AIM21284.1 - 0.075 13.5 0.0 0.24 11.9 0.0 1.9 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension HxlR PF01638.17 AIM21285.1 - 7.2e-13 48.2 0.0 1.2e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 HxlR-like helix-turn-helix PadR PF03551.14 AIM21285.1 - 0.0016 18.4 0.1 0.0025 17.7 0.1 1.3 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family Replic_Relax PF13814.6 AIM21285.1 - 0.0031 17.6 0.1 0.0031 17.6 0.1 1.4 2 0 0 2 2 2 1 Replication-relaxation FabA PF07977.13 AIM21287.1 - 2.9e-53 179.2 0.0 3.4e-53 179.0 0.0 1.1 1 0 0 1 1 1 1 FabA-like domain AAA_32 PF13654.6 AIM21288.1 - 2.8e-22 79.2 0.0 3.8e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain Lon_C PF05362.13 AIM21288.1 - 7.1e-10 38.8 0.0 1.3e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain MatP PF06303.12 AIM21289.1 - 2.3e-45 153.1 4.1 2.3e-45 153.1 4.1 1.6 2 0 0 2 2 2 1 MatP N-terminal domain MatP_C PF17414.2 AIM21289.1 - 5.5e-31 106.5 1.0 5.5e-31 106.5 1.0 1.7 2 0 0 2 2 2 1 MatP C-terminal ribbon-helix-helix domain RHH_4 PF13467.6 AIM21289.1 - 2e-05 24.4 0.6 8e-05 22.4 0.1 2.0 2 0 0 2 2 2 1 Ribbon-helix-helix domain PSK_trans_fac PF07704.11 AIM21289.1 - 0.052 14.3 0.4 0.052 14.3 0.4 2.6 2 1 0 2 2 2 0 Rv0623-like transcription factor Prok-TraM PF09228.10 AIM21289.1 - 0.54 10.6 4.6 4.4 7.7 0.2 2.6 2 1 1 3 3 3 0 Prokaryotic Transcriptional repressor TraM TMF_TATA_bd PF12325.8 AIM21289.1 - 1.4 9.2 6.6 0.4 10.9 1.0 2.5 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding CcdA PF07362.12 AIM21289.1 - 6.2 7.3 7.6 0.68 10.4 0.6 2.5 2 1 1 3 3 3 0 Post-segregation antitoxin CcdA OmpA_membrane PF01389.17 AIM21290.1 - 4.2e-72 241.7 4.2 5.8e-72 241.3 4.2 1.2 1 0 0 1 1 1 1 OmpA-like transmembrane domain OmpA PF00691.20 AIM21290.1 - 4e-23 81.6 0.0 8e-23 80.6 0.0 1.5 1 0 0 1 1 1 1 OmpA family OMP_b-brl PF13505.6 AIM21290.1 - 8.5e-22 78.1 13.9 1.3e-21 77.6 13.9 1.2 1 0 0 1 1 1 1 Outer membrane protein beta-barrel domain DUF2490 PF10677.9 AIM21290.1 - 0.022 14.7 0.2 1.6 8.6 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2490) Phage_T7_tail PF03906.14 AIM21290.1 - 0.048 13.3 0.0 0.092 12.4 0.0 1.5 1 0 0 1 1 1 0 Phage T7 tail fibre protein Pilus_CpaD PF09476.10 AIM21290.1 - 0.11 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) SulA PF03846.14 AIM21291.1 - 5.4e-54 181.0 3.1 6.8e-54 180.7 3.1 1.1 1 0 0 1 1 1 1 Cell division inhibitor SulA SymE_toxin PF08845.10 AIM21291.1 - 0.14 12.2 1.2 0.31 11.1 1.2 1.6 1 0 0 1 1 1 0 Toxin SymE, type I toxin-antitoxin system TfoX_N PF04993.13 AIM21292.1 - 8e-27 93.3 0.1 1.4e-26 92.5 0.1 1.4 1 0 0 1 1 1 1 TfoX N-terminal domain TfoX_C PF04994.13 AIM21292.1 - 1.6e-21 76.2 1.7 7.1e-21 74.1 0.2 2.2 2 0 0 2 2 2 1 TfoX C-terminal domain Cdd1 PF11731.8 AIM21292.1 - 0.12 12.6 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Pathogenicity locus FUSC-like PF12805.7 AIM21293.1 - 6.2e-109 363.5 9.8 6.2e-109 363.5 9.8 2.8 3 0 0 3 3 3 1 FUSC-like inner membrane protein yccS FUSC_2 PF13515.6 AIM21293.1 - 1.1e-23 83.8 13.9 1.1e-23 83.8 13.9 2.4 2 0 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.12 AIM21293.1 - 8.8e-05 21.3 2.9 8.8e-05 21.3 2.9 3.7 1 1 1 3 3 3 2 Fusaric acid resistance protein family ALMT PF11744.8 AIM21293.1 - 0.037 12.8 4.7 0.041 12.7 2.0 2.4 2 1 0 2 2 2 0 Aluminium activated malate transporter YccF PF03733.13 AIM21294.1 - 2.4e-28 98.6 26.8 9.3e-18 64.7 12.2 2.1 2 0 0 2 2 2 2 Inner membrane component domain Phage_holin_3_6 PF07332.11 AIM21294.1 - 0.41 10.7 5.9 1.5 8.9 0.1 2.1 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF5362 PF17319.2 AIM21294.1 - 2.2 8.2 10.7 0.098 12.5 2.8 2.4 2 1 0 2 2 2 0 Family of unknown function (DUF5362) Helicase_IV_N PF12462.8 AIM21295.1 - 3.5e-64 215.6 6.9 3.5e-64 215.6 6.9 2.9 4 0 0 4 4 4 1 DNA helicase IV / RNA helicase N terminal UvrD-helicase PF00580.21 AIM21295.1 - 1e-40 140.2 0.1 1.8e-39 136.1 0.0 2.3 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 AIM21295.1 - 2.3e-30 105.8 0.0 5.7e-30 104.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain UvrD_C PF13361.6 AIM21295.1 - 1.3e-13 51.1 0.7 4.2e-12 46.1 0.0 2.6 2 1 1 3 3 3 1 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 AIM21295.1 - 2.3e-11 43.3 0.0 3.4e-06 26.8 0.0 2.8 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 AIM21295.1 - 4.4e-09 36.3 0.6 2e-05 24.4 0.3 2.4 2 0 0 2 2 2 2 AAA domain AAA_12 PF13087.6 AIM21295.1 - 4.3e-05 23.2 0.0 0.002 17.8 0.0 2.9 2 1 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 AIM21295.1 - 0.0082 15.9 0.1 1.5 8.5 0.1 3.3 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase STAT_int PF02865.17 AIM21295.1 - 0.022 15.2 2.1 0.022 15.2 2.1 2.3 2 0 0 2 2 2 0 STAT protein, protein interaction domain DEAD PF00270.29 AIM21295.1 - 0.16 11.7 0.0 0.37 10.5 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_16 PF13191.6 AIM21295.1 - 6.9 7.0 10.5 43 4.4 7.5 3.4 1 1 1 2 2 2 0 AAA ATPase domain MGS PF02142.22 AIM21296.1 - 9.8e-21 73.8 0.0 1.5e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 MGS-like domain DUF2057 PF09829.9 AIM21297.1 - 1.5e-51 175.4 0.5 1.7e-51 175.2 0.5 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2057) CoA_binding_2 PF13380.6 AIM21298.1 - 9.3e-40 135.7 0.3 1.1e-39 135.5 0.3 1.1 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 AIM21298.1 - 7.5e-07 29.7 0.0 1.1e-06 29.2 0.0 1.2 1 0 0 1 1 1 1 CoA binding domain YccV-like PF08755.11 AIM21299.1 - 1.9e-20 73.1 0.0 2.2e-20 73.0 0.0 1.0 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Methyltrans_SAM PF10672.9 AIM21300.1 - 9.7e-30 103.7 0.0 1.4e-29 103.1 0.0 1.2 1 0 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase PUA_3 PF17785.1 AIM21300.1 - 9.8e-20 70.1 0.1 1.8e-19 69.3 0.1 1.5 1 0 0 1 1 1 1 PUA-like domain Cons_hypoth95 PF03602.15 AIM21300.1 - 1.2e-11 44.5 0.0 1.9e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.6 AIM21300.1 - 1.7e-11 44.2 0.2 4e-11 42.9 0.1 1.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 AIM21300.1 - 1.3e-06 28.1 0.0 2e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 AIM21300.1 - 6.2e-06 26.8 0.0 1.3e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 AIM21300.1 - 0.00025 20.8 0.0 0.00041 20.2 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_15 PF09445.10 AIM21300.1 - 0.00031 20.4 0.0 0.00049 19.7 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 AIM21300.1 - 0.00033 20.2 0.1 0.00049 19.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TRM PF02005.16 AIM21300.1 - 0.0037 16.5 0.0 0.0048 16.1 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_11 PF08241.12 AIM21300.1 - 0.012 16.2 0.2 0.031 14.9 0.0 1.7 2 0 0 2 2 1 0 Methyltransferase domain PUA PF01472.20 AIM21300.1 - 0.026 14.5 0.0 0.057 13.4 0.0 1.5 1 0 0 1 1 1 0 PUA domain Methyltransf_12 PF08242.12 AIM21300.1 - 0.034 14.9 0.2 0.077 13.7 0.2 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltr_RsmB-F PF01189.17 AIM21300.1 - 0.088 12.4 0.1 0.2 11.3 0.1 1.6 1 1 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Dioxygenase_C PF00775.21 AIM21300.1 - 0.11 11.9 0.0 3.6 7.0 0.0 2.2 2 0 0 2 2 2 0 Dioxygenase Methyltransf_10 PF05971.12 AIM21300.1 - 0.15 11.4 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 RNA methyltransferase Methyltransf_16 PF10294.9 AIM21300.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Acylphosphatase PF00708.18 AIM21301.1 - 7.6e-25 87.1 0.1 8.3e-25 87.0 0.1 1.0 1 0 0 1 1 1 1 Acylphosphatase DsrC PF04358.13 AIM21302.1 - 1.4e-45 154.2 0.0 1.5e-45 154.1 0.0 1.0 1 0 0 1 1 1 1 DsrC like protein Bax1-I PF01027.20 AIM21303.1 - 2.8e-40 138.4 32.5 3.2e-40 138.2 32.5 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF2583 PF10762.9 AIM21303.1 - 2.9 8.4 8.4 0.12 12.8 1.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2583) BofA PF07441.11 AIM21303.1 - 8.7 6.6 21.6 1.8 8.8 1.2 3.6 2 1 2 4 4 4 0 SigmaK-factor processing regulatory protein BofA Fimbrial PF00419.20 AIM21305.1 - 1.9e-12 47.7 4.7 2.6e-12 47.2 4.7 1.2 1 0 0 1 1 1 1 Fimbrial protein FimA PF16970.5 AIM21305.1 - 2.5 8.3 12.0 0.9 9.7 0.2 3.1 2 1 1 3 3 3 0 Type-1 fimbrial protein, A PapD_N PF00345.20 AIM21306.1 - 3.8e-43 146.4 0.1 5.4e-43 145.9 0.1 1.2 1 0 0 1 1 1 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain PapD_C PF02753.17 AIM21306.1 - 2.6e-07 30.9 0.2 7.5e-07 29.4 0.2 1.8 1 0 0 1 1 1 1 Pili assembly chaperone PapD, C-terminal domain Usher PF00577.20 AIM21307.1 - 3e-165 551.2 19.7 3.7e-165 550.9 19.7 1.1 1 0 0 1 1 1 1 Outer membrane usher protein PapC_N PF13954.6 AIM21307.1 - 8.4e-27 94.0 0.0 1.9e-26 92.9 0.0 1.6 1 0 0 1 1 1 1 PapC N-terminal domain PapC_C PF13953.6 AIM21307.1 - 8.2e-11 41.6 0.0 5.5e-10 38.9 0.0 2.3 2 0 0 2 2 2 1 PapC C-terminal domain Fimbrial PF00419.20 AIM21308.1 - 5e-14 52.8 3.4 5e-14 52.8 1.7 1.8 2 0 0 2 2 2 1 Fimbrial protein RelB PF04221.12 AIM21309.1 - 0.012 15.5 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 RelB antitoxin GerE PF00196.19 AIM21310.1 - 3.4e-18 64.9 0.1 4.5e-18 64.5 0.1 1.2 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4 PF04545.16 AIM21310.1 - 8.5e-06 25.2 0.0 1.8e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 AIM21310.1 - 2.2e-05 24.0 0.0 3.2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 AIM21310.1 - 0.00048 19.9 0.0 0.001 18.8 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_10 PF04967.12 AIM21310.1 - 0.0036 17.1 0.0 0.014 15.2 0.1 1.9 3 0 0 3 3 3 1 HTH DNA binding domain HTH_Tnp_ISL3 PF13542.6 AIM21310.1 - 0.012 15.1 0.1 0.035 13.5 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 P22_Cro PF14549.6 AIM21310.1 - 0.039 13.8 0.0 0.055 13.3 0.0 1.3 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro KORA PF16509.5 AIM21310.1 - 0.095 13.0 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 TrfB plasmid transcriptional repressor YdaS_antitoxin PF15943.5 AIM21310.1 - 0.098 12.5 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_5 PF01022.20 AIM21310.1 - 0.15 12.0 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Phage_terminase PF10668.9 AIM21310.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Phage terminase small subunit HTH_7 PF02796.15 AIM21310.1 - 0.18 11.9 0.0 0.47 10.6 0.0 1.7 1 1 1 2 2 2 0 Helix-turn-helix domain of resolvase Endonuclease_NS PF01223.23 AIM21311.1 - 1.1e-45 156.2 0.1 1.3e-45 156.0 0.1 1.0 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclea_NS_2 PF13930.6 AIM21311.1 - 0.019 15.1 0.0 0.032 14.3 0.0 1.4 1 0 0 1 1 1 0 DNA/RNA non-specific endonuclease FMN_red PF03358.15 AIM21313.1 - 1.1e-12 48.0 0.0 1.7e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.25 AIM21313.1 - 1.8e-05 25.0 0.1 4.1e-05 23.8 0.1 1.6 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.17 AIM21313.1 - 2.2e-05 24.3 0.0 2.6e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.7 AIM21313.1 - 4.9e-05 23.6 0.0 0.0026 18.0 0.0 2.1 1 1 1 2 2 2 1 Flavodoxin domain LysE PF01810.18 AIM21314.1 - 8.1e-33 113.5 11.7 9.4e-33 113.3 11.7 1.0 1 0 0 1 1 1 1 LysE type translocator Phage_holin_3_6 PF07332.11 AIM21314.1 - 0.12 12.5 17.3 0.46 10.5 1.1 2.4 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III LysR_substrate PF03466.20 AIM21315.1 - 3.5e-23 82.1 3.7 3.5e-23 82.1 3.7 1.4 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AIM21315.1 - 4.5e-19 68.1 4.3 9.4e-19 67.1 4.3 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 AIM21315.1 - 0.042 13.7 0.1 0.14 12.0 0.1 1.9 1 0 0 1 1 1 0 MarR family HTH_28 PF13518.6 AIM21315.1 - 0.063 13.4 0.4 0.16 12.1 0.4 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.6 AIM21315.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_3 PF01381.22 AIM21316.1 - 1.5e-15 56.9 0.3 2.8e-15 56.1 0.3 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 AIM21316.1 - 2.5e-11 43.7 1.3 2.5e-11 43.7 1.3 2.2 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_26 PF13443.6 AIM21316.1 - 2.7e-10 40.5 0.0 4.6e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain 2TM PF13239.6 AIM21316.1 - 1.1e-07 32.0 0.4 1.8e-07 31.3 0.4 1.3 1 0 0 1 1 1 1 2TM domain HTH_19 PF12844.7 AIM21316.1 - 2.6e-06 27.4 0.0 5.1e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 AIM21316.1 - 4.8e-06 26.3 0.2 1.2e-05 25.1 0.2 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AIM21316.1 - 6.7e-05 22.6 4.1 0.00053 19.7 0.2 3.2 2 1 1 3 3 3 1 Homeodomain-like domain HTH_37 PF13744.6 AIM21316.1 - 9.9e-05 22.2 0.2 9.9e-05 22.2 0.2 2.3 3 0 0 3 3 3 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 AIM21316.1 - 0.0021 17.5 0.4 0.014 14.9 0.1 2.3 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_29 PF13551.6 AIM21316.1 - 0.0086 16.1 0.1 0.046 13.7 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn helix HTH_38 PF13936.6 AIM21316.1 - 0.013 15.3 1.4 0.31 10.8 0.2 2.8 2 1 1 3 3 3 0 Helix-turn-helix domain HTH_35 PF13693.6 AIM21316.1 - 0.027 14.5 0.4 0.071 13.2 0.1 1.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_ISL3 PF13542.6 AIM21316.1 - 0.038 13.4 0.2 0.55 9.7 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.6 AIM21316.1 - 0.088 13.0 3.9 0.18 11.9 0.1 3.0 2 2 1 3 3 3 0 Helix-turn-helix domain LysM PF01476.20 AIM21316.1 - 0.28 11.3 0.7 2.2 8.4 0.0 2.6 3 0 0 3 3 3 0 LysM domain HTH_3 PF01381.22 AIM21317.1 - 2.6e-13 49.8 0.1 3.8e-13 49.3 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 AIM21317.1 - 4.1e-11 43.0 0.5 9.1e-11 41.9 0.5 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Cupin_2 PF07883.11 AIM21317.1 - 1.2e-08 34.5 0.0 2.1e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Cupin domain HTH_19 PF12844.7 AIM21317.1 - 1.3e-06 28.3 0.0 2.3e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 AIM21317.1 - 2.5e-06 27.8 0.0 4.3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain AraC_binding PF02311.19 AIM21317.1 - 0.0011 18.9 0.0 0.0027 17.6 0.0 1.6 1 0 0 1 1 1 1 AraC-like ligand binding domain HTH_25 PF13413.6 AIM21317.1 - 0.013 15.3 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain EamA PF00892.20 AIM21318.1 - 3.4e-27 95.3 35.0 2.9e-14 53.4 6.6 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 AIM21318.1 - 0.0063 15.9 0.1 0.0063 15.9 0.1 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family AA_permease PF00324.21 AIM21319.1 - 3.4e-118 395.3 48.6 3.7e-118 395.1 48.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 AIM21319.1 - 8.4e-47 159.9 50.9 1.1e-46 159.5 50.9 1.0 1 0 0 1 1 1 1 Amino acid permease DUF962 PF06127.11 AIM21319.1 - 0.011 15.8 6.8 0.11 12.6 4.2 3.9 1 1 1 2 2 2 0 Protein of unknown function (DUF962) SH PF01445.17 AIM21319.1 - 0.083 12.9 3.0 0.62 10.1 3.0 2.6 1 0 0 1 1 1 0 Viral small hydrophobic protein SNARE_assoc PF09335.11 AIM21320.1 - 8.7e-14 52.0 4.9 8.7e-14 52.0 4.9 1.4 2 0 0 2 2 2 1 SNARE associated Golgi protein MFS_1 PF07690.16 AIM21321.1 - 1.6e-37 129.3 44.1 1.6e-37 129.3 44.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily ABM PF03992.16 AIM21322.1 - 8.6e-14 51.4 0.1 1e-13 51.2 0.1 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase SH2_2 PF14633.6 AIM21322.1 - 0.13 11.6 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 SH2 domain Acetyltransf_3 PF13302.7 AIM21324.1 - 1e-26 94.3 0.0 1.4e-26 93.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AIM21324.1 - 4.2e-07 30.2 0.0 6.1e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 AIM21324.1 - 2.5e-05 24.1 0.0 4.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 AIM21324.1 - 6.9e-05 23.0 0.0 8.6e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 AIM21324.1 - 0.00012 21.7 1.8 0.00033 20.3 0.1 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AIM21324.1 - 0.01 16.2 0.0 0.015 15.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 AIM21324.1 - 0.014 14.9 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase Calx-beta PF03160.14 AIM21324.1 - 0.1 12.8 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Calx-beta domain ECH_1 PF00378.20 AIM21325.1 - 1.2e-45 155.8 0.2 1.4e-45 155.5 0.2 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AIM21325.1 - 2e-27 96.6 0.4 7e-27 94.8 0.4 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase MFS_1 PF07690.16 AIM21326.1 - 3e-36 125.1 47.5 3e-36 125.1 47.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 AIM21326.1 - 4.5e-07 29.5 32.2 4.5e-07 29.5 32.2 2.0 1 1 1 2 2 2 2 Uncharacterised MFS-type transporter YbfB Aminotran_1_2 PF00155.21 AIM21327.1 - 1.5e-69 234.9 0.0 1.9e-69 234.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 AIM21327.1 - 2.7e-05 22.9 0.0 4e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Thiolase_N PF00108.23 AIM21328.1 - 3.5e-73 246.2 0.0 4.7e-73 245.7 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 AIM21328.1 - 2.7e-38 130.4 1.1 4.1e-38 129.8 0.4 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 AIM21328.1 - 1.5e-05 24.7 0.2 3.3e-05 23.6 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 AIM21328.1 - 0.38 10.7 2.2 2.3 8.1 0.1 2.7 2 1 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 3HCDH_N PF02737.18 AIM21329.1 - 2e-48 164.6 0.4 3.3e-48 164.0 0.4 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 AIM21329.1 - 7.1e-34 116.3 0.5 1.1e-22 80.5 0.0 3.0 4 0 0 4 4 4 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 3HCDH_RFF PF18321.1 AIM21329.1 - 3.3e-09 37.1 4.3 3.8e-09 36.8 1.3 2.5 2 0 0 2 2 2 1 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain Autoind_bind PF03472.15 AIM21330.1 - 1.5e-27 95.9 0.7 1.9e-27 95.6 0.7 1.1 1 0 0 1 1 1 1 Autoinducer binding domain GerE PF00196.19 AIM21330.1 - 2.6e-17 62.1 1.1 3.5e-17 61.7 0.2 1.7 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AIM21330.1 - 5.4e-05 22.8 0.0 0.00011 21.8 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AIM21330.1 - 0.00013 21.4 0.0 0.0015 18.0 0.0 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_38 PF13936.6 AIM21330.1 - 0.0003 20.5 0.0 0.00085 19.0 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AIM21330.1 - 0.0023 17.7 0.0 0.0055 16.5 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 AIM21330.1 - 0.006 16.6 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_10 PF04967.12 AIM21330.1 - 0.0071 16.1 0.5 0.029 14.2 0.0 2.2 2 0 0 2 2 2 1 HTH DNA binding domain HTH_40 PF14493.6 AIM21330.1 - 0.035 14.6 0.0 0.075 13.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_28 PF13518.6 AIM21330.1 - 0.055 13.6 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_11 PF08279.12 AIM21330.1 - 0.12 12.4 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 HTH domain HTH_20 PF12840.7 AIM21330.1 - 0.12 12.5 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Usp PF00582.26 AIM21331.1 - 5.1e-24 85.4 0.1 5.9e-24 85.2 0.1 1.0 1 0 0 1 1 1 1 Universal stress protein family Ldh_2 PF02615.14 AIM21333.1 - 4.1e-100 335.2 0.1 4.6e-100 335.0 0.1 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase AA_permease_2 PF13520.6 AIM21334.1 - 2.4e-40 138.7 47.8 2.4e-40 138.7 47.8 1.8 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.21 AIM21334.1 - 2.3e-23 82.5 33.5 2.3e-23 82.5 33.5 2.1 2 0 0 2 2 2 1 Amino acid permease Aldedh PF00171.22 AIM21335.1 - 1.4e-42 145.8 0.0 2e-42 145.3 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DHDPS PF00701.22 AIM21336.1 - 6.4e-60 202.3 0.0 7.3e-60 202.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Type_III_YscG PF09477.10 AIM21336.1 - 0.029 14.4 0.0 0.054 13.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial type II secretion system chaperone protein (type_III_yscG) CbiX PF01903.17 AIM21336.1 - 0.044 14.1 0.1 0.11 12.8 0.1 1.6 1 0 0 1 1 1 0 CbiX Peripla_BP_1 PF00532.21 AIM21336.1 - 0.058 12.8 0.1 0.33 10.3 0.1 1.9 2 0 0 2 2 2 0 Periplasmic binding proteins and sugar binding domain of LacI family HTH_18 PF12833.7 AIM21337.1 - 5.9e-22 77.7 0.1 1.6e-21 76.3 0.1 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain PAS_4 PF08448.10 AIM21337.1 - 1.1e-19 70.7 0.0 2.7e-19 69.4 0.0 1.7 2 0 0 2 2 2 1 PAS fold HTH_AraC PF00165.23 AIM21337.1 - 7.2e-12 45.1 0.0 2.2e-08 34.0 0.0 2.7 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family PAS_9 PF13426.7 AIM21337.1 - 0.00092 19.4 0.0 0.0088 16.3 0.0 2.2 2 0 0 2 2 2 1 PAS domain HRDC PF00570.23 AIM21337.1 - 0.056 13.4 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 HRDC domain DUF4461 PF14688.6 AIM21337.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4461) Pro_racemase PF05544.11 AIM21338.1 - 8.4e-96 320.8 0.0 9.5e-96 320.6 0.0 1.0 1 0 0 1 1 1 1 Proline racemase DAP_epimerase PF01678.19 AIM21338.1 - 0.0034 17.6 0.1 0.024 14.8 0.0 2.0 2 0 0 2 2 2 1 Diaminopimelate epimerase PhzC-PhzF PF02567.16 AIM21338.1 - 0.0052 16.3 0.0 0.0085 15.6 0.0 1.2 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein DAO PF01266.24 AIM21339.1 - 2.1e-52 178.9 9.7 2.4e-52 178.7 9.7 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AIM21339.1 - 4.5e-07 30.0 0.3 1.8e-06 28.1 0.3 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 AIM21339.1 - 1.9e-05 23.9 0.3 0.0036 16.4 1.3 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 AIM21339.1 - 2.5e-05 23.7 0.6 0.01 15.1 0.7 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 AIM21339.1 - 0.00011 22.2 2.3 0.063 13.3 0.1 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 AIM21339.1 - 0.0011 18.2 4.4 0.0012 18.0 2.7 1.9 1 1 1 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 AIM21339.1 - 0.0098 15.3 1.4 0.014 14.8 1.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.16 AIM21339.1 - 0.011 15.4 0.5 0.023 14.4 0.5 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 AIM21339.1 - 0.011 15.6 2.6 0.015 15.2 0.9 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 AIM21339.1 - 0.028 14.9 0.5 0.061 13.9 0.1 1.7 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 AIM21339.1 - 0.064 12.3 0.8 2.4 7.1 0.3 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 AIM21339.1 - 0.07 12.4 0.1 0.13 11.5 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Sacchrp_dh_NADP PF03435.18 AIM21339.1 - 0.092 13.0 0.7 1.4 9.2 0.4 2.3 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain HI0933_like PF03486.14 AIM21339.1 - 0.15 10.7 1.5 0.27 9.9 1.5 1.4 1 0 0 1 1 1 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.14 AIM21339.1 - 0.21 11.2 0.3 0.36 10.4 0.3 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain EccE PF11203.8 AIM21339.1 - 1.5 9.2 7.8 0.16 12.3 1.2 2.7 3 1 1 4 4 3 0 Putative type VII ESX secretion system translocon, EccE Fer2_4 PF13510.6 AIM21340.1 - 8.5e-19 67.4 0.3 9.4e-19 67.2 0.3 1.0 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 AIM21340.1 - 0.0002 21.3 1.9 0.00038 20.4 1.9 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DHODB_Fe-S_bind PF10418.9 AIM21340.1 - 0.0032 17.3 4.0 0.0059 16.4 4.0 1.4 1 0 0 1 1 1 1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Fer2 PF00111.27 AIM21340.1 - 4.3 7.4 12.2 20 5.2 12.2 2.2 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Pyr_redox_2 PF07992.14 AIM21341.1 - 8.1e-22 77.8 2.3 2.4e-21 76.3 2.3 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AIM21341.1 - 2.7e-08 33.6 0.5 2.7e-08 33.6 0.5 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AIM21341.1 - 1.4e-07 31.0 10.1 2.3e-06 27.0 1.0 3.3 3 1 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.6 AIM21341.1 - 1.4e-06 28.4 1.5 1.9e-06 28.0 0.1 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 AIM21341.1 - 2.9e-06 26.3 5.5 3.5e-06 26.0 0.2 2.7 3 0 0 3 3 3 1 HI0933-like protein DAO PF01266.24 AIM21341.1 - 4.1e-06 26.6 3.6 1.2e-05 25.1 3.7 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 AIM21341.1 - 4.1e-06 26.2 1.1 0.00014 21.2 0.1 2.2 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 AIM21341.1 - 2.6e-05 23.5 8.8 0.0032 16.6 0.4 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 AIM21341.1 - 3.7e-05 23.1 3.0 8.8e-05 21.9 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.6 AIM21341.1 - 0.00012 22.4 0.6 0.39 11.2 0.1 2.8 2 1 0 2 2 2 2 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 AIM21341.1 - 0.00023 20.5 3.0 0.0016 17.7 0.5 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase XdhC_C PF13478.6 AIM21341.1 - 0.00031 21.2 0.1 0.6 10.6 0.0 2.5 2 0 0 2 2 2 2 XdhC Rossmann domain NAD_binding_9 PF13454.6 AIM21341.1 - 0.00089 19.3 0.0 0.0019 18.2 0.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 AIM21341.1 - 0.0011 19.5 1.7 0.14 12.7 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 AIM21341.1 - 0.0047 16.2 0.1 0.0047 16.2 0.1 2.5 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 AIM21341.1 - 0.04 14.2 0.1 1.3 9.3 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain LpxI_N PF17930.1 AIM21341.1 - 0.054 13.4 0.4 0.054 13.4 0.4 1.9 2 0 0 2 2 2 0 LpxI N-terminal domain 2-Hacid_dh_C PF02826.19 AIM21341.1 - 0.15 11.4 1.7 11 5.3 0.5 2.7 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 AIM21341.1 - 1.1 8.2 6.4 0.22 10.5 0.4 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Fer2_BFD PF04324.15 AIM21341.1 - 1.6 9.1 6.4 7.4 7.0 6.4 2.2 1 1 0 1 1 1 0 BFD-like [2Fe-2S] binding domain DUF2846 PF11008.8 AIM21344.1 - 0.0003 20.8 0.0 0.00037 20.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2846) Qn_am_d_aIII PF09099.10 AIM21344.1 - 0.028 14.8 0.0 6.3 7.3 0.0 2.3 2 0 0 2 2 2 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain III GlpM PF06942.12 AIM21345.1 - 1.8e-46 157.0 14.3 2e-46 156.8 14.3 1.0 1 0 0 1 1 1 1 GlpM protein DUF3021 PF11457.8 AIM21345.1 - 0.052 13.9 11.3 0.068 13.5 11.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) DUF2594 PF10769.9 AIM21346.1 - 1.3e-38 130.9 0.4 1.4e-38 130.7 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2594) DUF5460 PF17544.2 AIM21346.1 - 0.017 14.2 0.1 0.017 14.2 0.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5460) Response_reg PF00072.24 AIM21347.1 - 8.3e-31 106.5 0.0 1.3e-30 105.9 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AIM21347.1 - 1.3e-19 69.5 1.5 2.7e-19 68.5 0.2 2.1 2 1 1 3 3 3 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AIM21347.1 - 1.6e-05 24.5 0.6 4.1e-05 23.2 0.1 1.9 1 1 1 2 2 2 1 Sigma-70, region 4 HTH_23 PF13384.6 AIM21347.1 - 0.0039 17.0 0.1 0.016 15.0 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Mga PF08280.11 AIM21347.1 - 0.026 14.6 0.1 0.089 12.8 0.1 1.9 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain HTH_29 PF13551.6 AIM21347.1 - 0.052 13.6 0.1 0.19 11.8 0.0 2.0 3 0 0 3 3 3 0 Winged helix-turn helix HTH_24 PF13412.6 AIM21347.1 - 0.071 12.7 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 AIM21347.1 - 0.087 12.7 0.2 0.37 10.7 0.1 2.0 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_40 PF14493.6 AIM21347.1 - 0.1 13.1 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain UvrC_HhH_N PF08459.11 AIM21348.1 - 6.3e-46 156.1 0.0 1.9e-45 154.6 0.0 1.8 2 0 0 2 2 2 1 UvrC Helix-hairpin-helix N-terminal GIY-YIG PF01541.24 AIM21348.1 - 8.2e-13 48.4 0.3 1.7e-12 47.4 0.3 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain UVR PF02151.19 AIM21348.1 - 7.7e-10 38.2 2.1 2e-09 36.9 2.1 1.8 1 0 0 1 1 1 1 UvrB/uvrC motif HHH_5 PF14520.6 AIM21348.1 - 1.6e-08 35.0 0.1 3.8e-08 33.8 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.23 AIM21348.1 - 5.8e-08 32.2 0.1 0.00019 21.2 0.0 2.7 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_2 PF12826.7 AIM21348.1 - 3.8e-05 23.7 0.0 8.4e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_3 PF12836.7 AIM21348.1 - 8.5e-05 22.7 0.4 0.044 14.1 0.1 2.8 2 0 0 2 2 2 2 Helix-hairpin-helix motif CDP-OH_P_transf PF01066.21 AIM21349.1 - 2.9e-17 63.2 0.8 2.9e-17 63.2 0.8 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF5413 PF17434.2 AIM21350.1 - 2e-06 28.2 2.4 2.6e-06 27.8 2.4 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5413) DcuA_DcuB PF03605.14 AIM21351.1 - 3.8e-146 486.7 20.2 4.4e-146 486.5 20.2 1.0 1 0 0 1 1 1 1 Anaerobic c4-dicarboxylate membrane transporter CitMHS PF03600.16 AIM21351.1 - 0.00097 18.4 26.7 0.0017 17.6 26.7 1.4 1 0 0 1 1 1 1 Citrate transporter 4HBT PF03061.22 AIM21352.1 - 2.5e-09 37.4 0.2 3.5e-09 36.9 0.2 1.2 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 AIM21352.1 - 0.00066 19.8 0.1 0.00096 19.3 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4442) 4HBT_3 PF13622.6 AIM21352.1 - 0.0015 18.8 0.0 0.0017 18.7 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF2767 PF10965.8 AIM21353.1 - 0.0023 17.9 0.1 0.0032 17.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2767) VHS PF00790.19 AIM21353.1 - 0.013 15.4 0.0 0.014 15.2 0.0 1.1 1 0 0 1 1 1 0 VHS domain DUF2513 PF10711.9 AIM21355.1 - 0.051 13.9 0.0 0.057 13.7 0.0 1.1 1 0 0 1 1 1 0 Hypothetical protein (DUF2513) YjcQ PF09639.10 AIM21355.1 - 0.081 13.1 0.0 0.094 12.9 0.0 1.2 1 0 0 1 1 1 0 YjcQ protein DUF4803 PF16061.5 AIM21355.1 - 0.095 12.1 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4803) GMC_oxred_N PF00732.19 AIM21356.1 - 2.8e-57 194.4 0.0 3.6e-57 194.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 AIM21356.1 - 5e-35 121.1 0.2 8.3e-35 120.4 0.2 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 AIM21356.1 - 1.2e-06 27.9 1.9 0.0032 16.6 0.6 2.3 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.22 AIM21356.1 - 3.2e-06 26.5 0.0 0.0062 15.7 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A HI0933_like PF03486.14 AIM21356.1 - 2.5e-05 23.2 0.3 0.0018 17.1 0.2 2.2 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 AIM21356.1 - 3.4e-05 23.1 0.2 6.9e-05 22.1 0.0 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 AIM21356.1 - 7.4e-05 22.9 0.8 0.00057 20.1 0.3 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AIM21356.1 - 0.00012 21.4 0.1 0.0067 15.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AIM21356.1 - 0.00012 21.8 0.8 0.0022 17.6 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 AIM21356.1 - 0.00018 20.9 0.0 0.1 11.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 AIM21356.1 - 0.0014 17.9 0.0 0.003 16.8 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 AIM21356.1 - 0.045 13.7 0.1 2.2 8.3 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 AIM21356.1 - 0.065 12.6 1.3 0.16 11.2 0.7 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase MelC1 PF06236.11 AIM21356.1 - 0.065 13.3 1.9 0.2 11.8 1.9 1.9 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 FAD_binding_3 PF01494.19 AIM21356.1 - 0.076 12.2 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 AIM21356.1 - 0.14 11.0 0.2 0.21 10.4 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase LysR_substrate PF03466.20 AIM21357.1 - 3.4e-44 150.7 1.6 4.3e-44 150.4 1.6 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM21357.1 - 2.9e-17 62.4 0.8 7e-17 61.1 0.8 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AIM21357.1 - 0.025 14.4 0.1 0.075 12.9 0.1 1.8 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain MarR_2 PF12802.7 AIM21357.1 - 0.046 13.6 0.8 0.14 12.1 0.3 2.1 2 0 0 2 2 2 0 MarR family DDRGK PF09756.9 AIM21357.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 DDRGK domain Sugar_tr PF00083.24 AIM21358.1 - 2.8e-66 224.3 25.2 4.6e-66 223.5 25.2 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 AIM21358.1 - 5.3e-37 127.6 37.3 1.9e-26 92.8 17.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Osmo_CC PF08946.10 AIM21358.1 - 3.8e-22 78.3 7.1 6.4e-22 77.5 7.1 1.4 1 0 0 1 1 1 1 Osmosensory transporter coiled coil DUF5320 PF17253.2 AIM21358.1 - 0.21 12.7 0.0 0.61 11.2 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5320) OEP PF02321.18 AIM21359.1 - 1.5e-41 142.3 45.8 9.1e-22 77.8 19.0 2.4 3 0 0 3 3 3 2 Outer membrane efflux protein MacB_PCD PF12704.7 AIM21360.1 - 5.5e-36 124.8 5.9 5.5e-36 124.8 5.9 3.1 3 0 0 3 3 3 1 MacB-like periplasmic core domain ABC_tran PF00005.27 AIM21360.1 - 1.2e-29 103.6 0.0 2.2e-29 102.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsX PF02687.21 AIM21360.1 - 4.6e-11 43.0 10.9 5.2e-11 42.9 3.3 3.2 3 0 0 3 3 3 1 FtsX-like permease family SMC_N PF02463.19 AIM21360.1 - 0.00011 21.8 0.1 0.08 12.4 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AIM21360.1 - 0.00043 20.7 0.5 0.0015 19.0 0.5 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AIM21360.1 - 0.00054 19.6 0.1 0.0014 18.3 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 AIM21360.1 - 0.0017 18.2 0.4 0.048 13.5 0.0 2.4 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 AIM21360.1 - 0.012 15.5 0.2 0.034 14.0 0.2 1.7 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 AIM21360.1 - 0.063 13.4 0.2 0.18 11.9 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.6 AIM21360.1 - 0.069 13.4 0.0 0.3 11.3 0.0 2.1 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 AIM21360.1 - 0.11 12.0 0.8 0.37 10.3 0.1 2.2 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 AIM21360.1 - 0.12 12.2 0.2 12 5.6 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_23 PF13476.6 AIM21360.1 - 0.13 12.8 0.3 0.25 11.8 0.3 1.4 1 0 0 1 1 1 0 AAA domain DUF1282 PF06930.12 AIM21360.1 - 0.17 11.6 8.1 0.13 12.0 5.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1282) AAA_33 PF13671.6 AIM21360.1 - 0.67 10.1 2.3 1.2 9.3 0.8 2.4 2 1 0 2 2 1 0 AAA domain HlyD_D23 PF16576.5 AIM21361.1 - 4.3e-17 62.0 5.9 4.9e-17 61.9 3.0 2.3 2 0 0 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AIM21361.1 - 1.7e-12 48.0 5.3 4e-08 33.9 0.4 3.4 2 1 1 3 3 3 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AIM21361.1 - 8.2e-11 41.6 6.9 6.9e-10 38.6 1.0 2.8 2 0 0 2 2 2 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AIM21361.1 - 5e-07 29.5 2.5 0.0034 17.2 0.1 2.6 2 0 0 2 2 2 2 Biotin-requiring enzyme Peptidase_M23 PF01551.22 AIM21361.1 - 0.00018 21.6 0.2 0.23 11.7 0.0 2.6 2 0 0 2 2 2 2 Peptidase family M23 HlyD PF00529.20 AIM21361.1 - 0.0079 16.1 0.0 0.22 11.4 0.0 2.2 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS RnfC_N PF13375.6 AIM21361.1 - 0.027 14.4 1.7 0.21 11.6 0.1 2.9 2 1 1 3 3 3 0 RnfC Barrel sandwich hybrid domain BMFP PF04380.13 AIM21361.1 - 0.041 14.4 4.9 0.11 13.0 4.8 1.7 1 1 0 1 1 1 0 Membrane fusogenic activity PTS_EIIA_1 PF00358.20 AIM21361.1 - 0.041 13.6 0.2 2.4 7.9 0.0 2.5 2 0 0 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 FokI_N PF02981.15 AIM21361.1 - 0.062 13.5 0.5 0.57 10.4 0.0 2.4 2 1 0 3 3 3 0 Restriction endonuclease FokI, recognition domain DUF4131 PF13567.6 AIM21361.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Atg14 PF10186.9 AIM21361.1 - 0.23 10.5 2.0 0.31 10.1 2.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 OEP PF02321.18 AIM21361.1 - 0.35 10.6 16.6 0.58 9.9 11.6 2.3 2 0 0 2 2 2 0 Outer membrane efflux protein DUF4200 PF13863.6 AIM21361.1 - 4.1 7.8 11.7 21 5.6 11.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) GIY-YIG PF01541.24 AIM21362.1 - 0.0013 19.0 0.0 0.0025 18.0 0.0 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain Anti-adapt_IraP PF10796.9 AIM21363.1 - 5.6e-06 26.8 2.3 8e-06 26.3 2.3 1.3 1 1 0 1 1 1 1 Sigma-S stabilisation anti-adaptor protein HD_2 PF12917.7 AIM21363.1 - 0.013 15.3 0.8 0.016 15.0 0.7 1.3 1 1 0 1 1 1 0 HD containing hydrolase-like enzyme RasGAP_C PF03836.15 AIM21363.1 - 0.015 15.4 1.3 0.017 15.2 1.3 1.1 1 0 0 1 1 1 0 RasGAP C-terminus DNA_Packaging PF11053.8 AIM21363.1 - 0.12 12.2 2.0 0.14 12.0 2.0 1.2 1 0 0 1 1 1 0 Terminase DNA packaging enzyme VWA_3 PF13768.6 AIM21363.1 - 0.12 12.3 1.3 0.14 12.1 1.3 1.1 1 0 0 1 1 1 0 von Willebrand factor type A domain ANAPC2 PF08672.11 AIM21363.1 - 0.12 12.9 0.4 2.9 8.5 0.1 2.4 2 0 0 2 2 2 0 Anaphase promoting complex (APC) subunit 2 YlaC PF10777.9 AIM21364.1 - 4.1e-63 211.8 0.2 4.7e-63 211.7 0.2 1.0 1 0 0 1 1 1 1 Inner membrane protein YlaC DUF2207 PF09972.9 AIM21364.1 - 0.095 11.4 0.3 0.11 11.2 0.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) GPI2 PF06432.11 AIM21364.1 - 0.13 11.7 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase Peptidase_U4 PF03419.13 AIM21364.1 - 0.2 10.9 3.4 0.24 10.6 3.0 1.3 1 1 0 1 1 1 0 Sporulation factor SpoIIGA Na_H_Exchanger PF00999.21 AIM21366.1 - 5.4e-43 147.2 28.2 6.4e-43 147.0 28.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family CorC_HlyC PF03471.17 AIM21366.1 - 3.1e-14 52.8 0.2 5e-14 52.1 0.2 1.4 1 0 0 1 1 1 1 Transporter associated domain TrkA_C PF02080.21 AIM21366.1 - 3.5e-11 42.8 0.0 6.7e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 TrkA-C domain Acyl_transf_3 PF01757.22 AIM21369.1 - 2.1e-33 115.8 41.8 2.5e-33 115.6 41.8 1.1 1 0 0 1 1 1 1 Acyltransferase family DUF1624 PF07786.12 AIM21369.1 - 0.019 14.5 17.2 0.011 15.3 6.0 3.4 2 2 1 3 3 3 0 Protein of unknown function (DUF1624) Acyl_transf_3 PF01757.22 AIM21370.1 - 4.8e-31 108.1 45.5 6e-31 107.7 45.5 1.1 1 0 0 1 1 1 1 Acyltransferase family Adeno_E3_CR2 PF02439.15 AIM21370.1 - 0.25 11.1 2.8 0.92 9.3 0.3 2.5 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 MdoG PF04349.12 AIM21371.1 - 8.9e-197 654.7 0.0 1e-196 654.6 0.0 1.0 1 0 0 1 1 1 1 Periplasmic glucan biosynthesis protein, MdoG Glycos_transf_2 PF00535.26 AIM21372.1 - 5.8e-24 84.8 0.1 1.2e-23 83.8 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 AIM21372.1 - 7.2e-11 42.4 12.2 7.2e-11 42.4 12.2 3.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 AIM21372.1 - 9.2e-09 35.0 0.0 1e-07 31.6 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 21 DUF1375 PF07119.12 AIM21373.1 - 1.7e-05 25.1 9.6 0.00011 22.5 4.8 2.4 2 1 1 3 3 3 2 Protein of unknown function (DUF1375) Acetyltransf_1 PF00583.25 AIM21374.1 - 0.0013 18.9 0.0 0.002 18.3 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AIM21374.1 - 0.05 14.0 0.0 0.16 12.4 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AIM21374.1 - 0.06 13.3 0.0 9.8 6.1 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AIM21374.1 - 0.11 12.6 0.0 1.8 8.6 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AIM21374.1 - 0.11 13.2 0.0 0.29 11.8 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain MsyB PF13984.6 AIM21375.1 - 5.9e-59 197.7 9.5 6.6e-59 197.6 9.5 1.0 1 0 0 1 1 1 1 MsyB protein HMGL-like PF00682.19 AIM21376.1 - 1e-71 241.6 0.0 1.3e-71 241.3 0.0 1.1 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 AIM21376.1 - 5.8e-19 68.3 0.0 9.5e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain HTH_18 PF12833.7 AIM21377.1 - 1.9e-23 82.5 0.6 3.3e-23 81.7 0.6 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AIM21377.1 - 9.5e-15 54.3 0.0 6.9e-06 26.0 0.0 2.3 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Cupin_2 PF07883.11 AIM21377.1 - 7e-08 32.1 0.4 1.2e-07 31.4 0.4 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 AIM21377.1 - 5.5e-07 29.6 0.3 1.4e-06 28.2 0.3 1.8 1 1 0 1 1 1 1 AraC-like ligand binding domain HTH_23 PF13384.6 AIM21377.1 - 0.00063 19.5 1.4 0.0053 16.5 0.1 2.3 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r4 PF04545.16 AIM21377.1 - 0.0063 16.0 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_8 PF02954.19 AIM21377.1 - 0.014 15.2 1.6 0.025 14.3 0.1 2.2 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family HTH_1 PF00126.27 AIM21377.1 - 0.026 14.5 1.4 1.3 9.0 0.1 2.6 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_20 PF12840.7 AIM21377.1 - 0.051 13.6 2.0 0.13 12.3 0.2 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_30 PF13556.6 AIM21377.1 - 0.065 13.0 0.9 0.18 11.7 0.9 1.8 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_32 PF13565.6 AIM21377.1 - 0.12 13.1 1.3 0.22 12.2 0.4 2.1 2 0 0 2 2 1 0 Homeodomain-like domain HTH_31 PF13560.6 AIM21377.1 - 0.12 12.8 9.0 0.048 14.0 4.8 2.5 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 AIM21377.1 - 0.15 11.5 1.0 1.5 8.3 0.1 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_5 PF01022.20 AIM21378.1 - 3.7e-14 52.3 0.4 5.3e-14 51.8 0.4 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 AIM21378.1 - 3.4e-09 36.6 2.5 3.7e-09 36.5 1.5 1.5 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.7 AIM21378.1 - 5.4e-07 29.4 0.9 8.9e-07 28.7 0.9 1.4 1 0 0 1 1 1 1 MarR family TrmB PF01978.19 AIM21378.1 - 1.3e-05 25.0 0.0 1.9e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.6 AIM21378.1 - 2.3e-05 24.3 0.3 4.3e-05 23.4 0.3 1.6 1 1 0 1 1 1 1 Crp-like helix-turn-helix domain HxlR PF01638.17 AIM21378.1 - 6.9e-05 22.6 0.1 8.1e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 HxlR-like helix-turn-helix Fe_dep_repress PF01325.19 AIM21378.1 - 7.6e-05 22.8 0.0 0.00014 22.0 0.0 1.4 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain Rrf2 PF02082.20 AIM21378.1 - 0.00013 22.2 0.1 0.00018 21.8 0.1 1.3 1 0 0 1 1 1 1 Transcriptional regulator MarR PF01047.22 AIM21378.1 - 0.00062 19.7 0.7 0.0016 18.3 0.1 1.9 2 0 0 2 2 2 1 MarR family TFIIE_alpha PF02002.17 AIM21378.1 - 0.0016 18.3 0.0 0.0023 17.8 0.0 1.3 1 1 0 1 1 1 1 TFIIE alpha subunit Cas_Csy1 PF09611.10 AIM21378.1 - 0.0018 17.4 0.1 0.002 17.3 0.1 1.0 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Csy1) HTH_IclR PF09339.10 AIM21378.1 - 0.0021 17.8 0.8 0.0021 17.8 0.8 2.1 2 1 0 2 2 2 1 IclR helix-turn-helix domain Arg_repressor PF01316.21 AIM21378.1 - 0.0037 17.0 0.1 0.0062 16.3 0.1 1.3 1 0 0 1 1 1 1 Arginine repressor, DNA binding domain HTH_24 PF13412.6 AIM21378.1 - 0.0056 16.2 0.1 0.0082 15.7 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding GntR PF00392.21 AIM21378.1 - 0.039 13.6 0.5 0.063 12.9 0.5 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_27 PF13463.6 AIM21378.1 - 0.041 14.4 0.1 0.072 13.6 0.1 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain DUF742 PF05331.11 AIM21378.1 - 0.045 13.6 0.2 0.049 13.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF742) HTH_1 PF00126.27 AIM21378.1 - 0.05 13.6 0.1 0.05 13.6 0.1 1.7 2 0 0 2 2 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Penicillinase_R PF03965.16 AIM21378.1 - 0.14 12.6 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 Penicillinase repressor Sulf_transp PF04143.14 AIM21379.1 - 0.0019 17.8 20.8 0.01 15.4 20.8 2.1 1 1 0 1 1 1 1 Sulphur transport Sulf_transp PF04143.14 AIM21380.1 - 0.00031 20.4 6.4 0.00031 20.4 6.4 2.3 1 1 0 2 2 2 1 Sulphur transport Glyoxalase PF00903.25 AIM21381.1 - 7.9e-09 35.8 0.1 9.8e-09 35.5 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Hepsin-SRCR PF09272.10 AIM21381.1 - 0.049 14.1 0.0 6.5 7.3 0.0 2.2 1 1 1 2 2 2 0 Hepsin, SRCR domain PTR2 PF00854.21 AIM21382.1 - 1.1e-63 215.4 28.2 8.4e-63 212.5 28.2 2.6 1 1 0 1 1 1 1 POT family MFS_1 PF07690.16 AIM21382.1 - 3.5e-24 85.4 65.3 4.7e-20 71.8 39.7 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily SID-1_RNA_chan PF13965.6 AIM21382.1 - 1.2 7.4 6.5 2.4 6.5 6.5 1.6 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 MFS_1 PF07690.16 AIM21383.1 - 7.5e-55 186.3 46.2 4.4e-36 124.5 29.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AIM21383.1 - 2.9e-16 59.4 27.0 3.9e-07 29.3 6.0 3.2 1 1 2 3 3 3 3 Sugar (and other) transporter MFS_1_like PF12832.7 AIM21383.1 - 1.2e-15 57.2 14.6 4.9e-15 55.3 14.6 1.8 1 1 0 1 1 1 1 MFS_1 like family MFS_3 PF05977.13 AIM21383.1 - 1.3e-05 23.8 26.1 3.7e-05 22.3 26.2 1.5 1 1 0 1 1 1 1 Transmembrane secretion effector MFS_4 PF06779.14 AIM21383.1 - 0.0013 18.1 27.7 0.015 14.6 2.3 3.1 1 1 2 3 3 3 3 Uncharacterised MFS-type transporter YbfB ATG22 PF11700.8 AIM21383.1 - 0.0024 16.6 1.9 0.0024 16.6 1.9 3.0 2 1 1 3 3 3 2 Vacuole effluxer Atg22 like CcmD PF04995.14 AIM21383.1 - 0.083 13.0 1.4 3 8.0 0.3 2.9 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) LacY_symp PF01306.19 AIM21383.1 - 0.33 9.7 15.1 0.77 8.5 7.9 2.3 1 1 1 2 2 2 0 LacY proton/sugar symporter YCII PF03795.14 AIM21384.1 - 2.8e-08 34.0 0.0 3.4e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Lip_A_acyltrans PF03279.13 AIM21385.1 - 1.8e-104 349.1 0.0 2e-104 348.9 0.0 1.0 1 0 0 1 1 1 1 Bacterial lipid A biosynthesis acyltransferase UPF0176_N PF17773.1 AIM21386.1 - 6e-22 77.8 0.0 9.6e-22 77.2 0.0 1.3 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese_C PF12368.8 AIM21386.1 - 2.4e-19 69.5 13.5 4.1e-19 68.7 13.5 1.4 1 0 0 1 1 1 1 Rhodanase C-terminal Rhodanese PF00581.20 AIM21386.1 - 5.3e-15 55.9 0.0 1.1e-14 54.8 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain YceI PF04264.13 AIM21387.1 - 1.6e-40 139.0 0.2 1.8e-40 138.8 0.2 1.0 1 0 0 1 1 1 1 YceI-like domain Ni_hydr_CYTB PF01292.20 AIM21388.1 - 1.3e-24 86.8 17.9 1.6e-24 86.5 17.9 1.1 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 DUF4405 PF14358.6 AIM21388.1 - 0.0003 21.3 15.5 0.00038 20.9 4.7 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF4405) DUF2208 PF09973.9 AIM21388.1 - 0.075 12.6 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) Cytochrom_B561 PF03188.16 AIM21388.1 - 2 8.5 11.9 2.1 8.5 6.8 2.6 2 1 0 2 2 2 0 Eukaryotic cytochrome b561 AI-2E_transport PF01594.16 AIM21389.1 - 2.5e-72 243.8 37.3 2.9e-72 243.6 37.3 1.0 1 0 0 1 1 1 1 AI-2E family transporter DUF4389 PF14333.6 AIM21389.1 - 0.13 12.2 0.2 0.13 12.2 0.2 4.7 4 1 1 5 5 5 0 Domain of unknown function (DUF4389) FtsX PF02687.21 AIM21391.1 - 0.12 12.9 3.8 0.15 12.5 3.8 1.2 1 0 0 1 1 1 0 FtsX-like permease family NPCC PF08058.11 AIM21391.1 - 0.28 11.2 2.4 0.32 11.0 2.4 1.1 1 0 0 1 1 1 0 Nuclear pore complex component ADH_zinc_N PF00107.26 AIM21392.1 - 5.2e-08 32.9 0.1 9e-08 32.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AIM21392.1 - 0.0017 18.2 0.0 0.004 17.0 0.0 1.6 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF2770 PF10968.8 AIM21393.1 - 9e-12 44.7 8.4 1e-11 44.6 8.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2770) GerE PF00196.19 AIM21394.1 - 8.8e-15 54.0 0.0 1.4e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family AbiEi_2 PF09952.9 AIM21394.1 - 0.023 15.0 0.0 0.034 14.4 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system HTH_22 PF13309.6 AIM21394.1 - 0.081 13.0 0.1 0.19 11.8 0.1 1.5 1 0 0 1 1 1 0 HTH domain HTH_23 PF13384.6 AIM21394.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain DAO PF01266.24 AIM21395.1 - 8.2e-45 153.9 0.1 9.7e-45 153.7 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 AIM21395.1 - 0.00024 20.5 0.1 0.091 12.0 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 AIM21395.1 - 0.00033 20.0 0.0 0.00049 19.4 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 AIM21395.1 - 0.0024 17.2 0.0 0.0041 16.4 0.0 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AIM21395.1 - 0.0025 16.9 0.4 0.02 14.0 0.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 AIM21395.1 - 0.0026 17.2 2.0 0.008 15.6 2.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AIM21395.1 - 0.0053 17.0 0.1 0.011 15.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 AIM21395.1 - 0.012 14.7 0.4 0.024 13.7 0.3 1.5 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 AIM21395.1 - 0.025 13.3 0.3 1.5 7.4 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.19 AIM21395.1 - 0.16 11.2 0.1 0.25 10.6 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain BssS PF13991.6 AIM21396.1 - 5.5e-38 128.9 0.2 6.2e-38 128.7 0.2 1.0 1 0 0 1 1 1 1 BssS protein family HTH_25 PF13413.6 AIM21396.1 - 0.096 12.6 0.1 3.8 7.5 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain Pox_P4A PF03395.14 AIM21397.1 - 0.15 9.6 0.0 0.17 9.5 0.0 1.0 1 0 0 1 1 1 0 Poxvirus P4A protein DinI PF06183.13 AIM21398.1 - 3.3e-28 97.8 0.0 3.9e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 DinI-like family Amidohydro_1 PF01979.20 AIM21399.1 - 2e-20 73.4 0.0 2.7e-20 73.0 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.14 AIM21399.1 - 0.0048 16.7 0.0 0.01 15.7 0.0 1.6 2 0 0 2 2 2 1 Amidohydrolase ABM PF03992.16 AIM21400.1 - 3.2e-17 62.4 0.6 3.6e-17 62.2 0.6 1.0 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase RNase_E_G PF10150.9 AIM21401.1 - 6.7e-92 307.7 1.3 7.7e-92 307.5 0.0 1.8 2 0 0 2 2 2 1 Ribonuclease E/G family PNPase_C PF12111.8 AIM21401.1 - 5.8e-19 67.2 4.2 5.8e-19 67.2 4.2 2.7 2 0 0 2 2 2 1 Polyribonucleotide phosphorylase C terminal S1 PF00575.23 AIM21401.1 - 1.5e-16 60.5 0.0 3.5e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 S1 RNA binding domain PseudoU_synth_2 PF00849.22 AIM21402.1 - 5.4e-29 101.3 0.0 8.2e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 AIM21402.1 - 7.6e-09 35.1 1.8 1.6e-08 34.1 1.8 1.6 1 0 0 1 1 1 1 S4 domain Maf PF02545.14 AIM21403.1 - 3.7e-46 157.0 0.0 4.1e-46 156.9 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein YceD PF02620.17 AIM21404.1 - 4.9e-18 65.4 0.6 7.2e-18 64.9 0.6 1.3 1 0 0 1 1 1 1 Large ribosomal RNA subunit accumulation protein YceD Ribosomal_L32p PF01783.23 AIM21405.1 - 3e-19 69.0 0.4 3.3e-19 68.9 0.4 1.0 1 0 0 1 1 1 1 Ribosomal L32p protein family FA_synthesis PF02504.15 AIM21406.1 - 5.9e-114 380.5 0.1 6.7e-114 380.3 0.1 1.0 1 0 0 1 1 1 1 Fatty acid synthesis protein ACP_syn_III_C PF08541.10 AIM21407.1 - 4.5e-37 126.1 1.1 2.1e-36 124.0 0.1 2.6 2 1 1 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 AIM21407.1 - 3.4e-32 110.1 0.7 8.6e-32 108.8 0.7 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Chal_sti_synt_N PF00195.19 AIM21407.1 - 7.5e-07 28.8 1.3 1.2e-06 28.1 1.3 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain HMG_CoA_synt_N PF01154.17 AIM21407.1 - 7.1e-05 22.7 0.2 0.00012 22.1 0.2 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal FAE1_CUT1_RppA PF08392.12 AIM21407.1 - 0.00018 20.9 0.1 0.00033 20.0 0.0 1.4 2 0 0 2 2 2 1 FAE1/Type III polyketide synthase-like protein Thiolase_N PF00108.23 AIM21407.1 - 0.0002 20.8 2.8 0.0002 20.8 2.8 1.7 2 1 0 2 2 2 1 Thiolase, N-terminal domain Acyl_transf_1 PF00698.21 AIM21408.1 - 3.1e-41 141.9 1.2 3.7e-41 141.7 1.2 1.0 1 0 0 1 1 1 1 Acyl transferase domain SAT PF16073.5 AIM21408.1 - 0.052 13.3 0.0 0.12 12.1 0.0 1.6 1 1 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis adh_short_C2 PF13561.6 AIM21409.1 - 8.1e-66 221.9 7.0 9.2e-66 221.7 7.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AIM21409.1 - 2.7e-60 203.2 3.5 3.3e-60 202.9 3.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AIM21409.1 - 1.3e-18 67.6 1.4 1.8e-18 67.1 1.4 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 AIM21409.1 - 9e-05 22.4 1.6 0.00012 22.1 1.6 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 AIM21409.1 - 0.0018 17.8 0.2 0.0028 17.1 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DFP PF04127.15 AIM21409.1 - 0.031 14.1 1.8 0.26 11.1 0.3 2.3 1 1 1 2 2 2 0 DNA / pantothenate metabolism flavoprotein PP-binding PF00550.25 AIM21410.1 - 3e-15 56.3 0.8 3.3e-15 56.2 0.8 1.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 AIM21410.1 - 4.5e-07 30.0 1.3 5.1e-07 29.8 1.3 1.2 1 0 0 1 1 1 1 Acyl-carrier DUF1896 PF08989.10 AIM21410.1 - 0.02 15.0 0.1 0.022 14.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1896) Ribosomal_L50 PF10501.9 AIM21410.1 - 0.042 14.0 0.0 0.053 13.7 0.0 1.4 1 1 0 1 1 1 0 Ribosomal subunit 39S ketoacyl-synt PF00109.26 AIM21411.1 - 7.1e-62 209.3 1.8 7.1e-62 209.3 1.8 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 AIM21411.1 - 1e-41 141.6 0.8 2e-41 140.7 0.8 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 AIM21411.1 - 5.2e-05 22.7 3.1 9.6e-05 21.9 0.8 2.2 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 AIM21411.1 - 0.0027 17.5 4.0 0.34 10.8 0.0 3.2 3 1 0 3 3 3 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Aminotran_4 PF01063.19 AIM21412.1 - 2.9e-41 141.8 0.0 3.6e-41 141.5 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV YceG PF02618.16 AIM21413.1 - 1.2e-83 280.8 0.0 1.4e-83 280.6 0.0 1.0 1 0 0 1 1 1 1 YceG-like family GerE PF00196.19 AIM21413.1 - 0.017 14.7 0.2 0.38 10.3 0.0 2.8 3 0 0 3 3 3 0 Bacterial regulatory proteins, luxR family DIMCO_N PF16844.5 AIM21413.1 - 0.085 13.2 0.0 0.4 11.0 0.0 2.0 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor, N-terminal Thymidylate_kin PF02223.17 AIM21414.1 - 4.1e-57 192.9 0.0 4.6e-57 192.7 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase dNK PF01712.19 AIM21414.1 - 0.00015 21.7 0.0 0.027 14.3 0.0 2.1 2 0 0 2 2 2 2 Deoxynucleoside kinase AAA_28 PF13521.6 AIM21414.1 - 0.011 16.0 0.0 0.015 15.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AIM21414.1 - 0.037 13.7 0.0 0.067 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AIM21414.1 - 0.053 14.1 0.0 0.62 10.6 0.0 2.2 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 AIM21414.1 - 0.079 12.9 0.1 1.2 9.1 0.0 2.1 2 0 0 2 2 2 0 NTPase AAA_22 PF13401.6 AIM21414.1 - 0.081 13.2 0.1 0.21 11.8 0.0 1.8 1 1 1 2 2 2 0 AAA domain HTH_Tnp_Tc3_2 PF01498.18 AIM21414.1 - 0.12 12.7 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Transposase DNApol3-delta_C PF09115.10 AIM21415.1 - 8.5e-46 155.3 12.7 1.8e-45 154.2 12.7 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit, C terminal DNA_pol3_delta2 PF13177.6 AIM21415.1 - 4.6e-44 150.1 0.0 1.4e-43 148.5 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase III, delta subunit CCP_MauG PF03150.14 AIM21415.1 - 0.019 15.6 0.0 0.033 14.8 0.0 1.4 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase TatD_DNase PF01026.21 AIM21416.1 - 3.6e-76 255.9 0.0 4.1e-76 255.7 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase TMEM252 PF15664.5 AIM21416.1 - 0.062 13.0 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 252 family PTS_EIIC PF02378.18 AIM21417.1 - 4.1e-82 275.8 34.6 4.1e-82 275.8 34.6 1.7 2 0 0 2 2 2 1 Phosphotransferase system, EIIC PTS_EIIB PF00367.20 AIM21417.1 - 3e-14 52.2 0.1 5.1e-14 51.5 0.1 1.4 1 0 0 1 1 1 1 phosphotransferase system, EIIB MscS_TM PF12794.7 AIM21417.1 - 0.39 9.5 3.6 0.84 8.4 2.6 2.1 1 1 1 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 DUF4180 PF13788.6 AIM21418.1 - 8.9e-35 119.0 0.0 9.9e-35 118.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4180) Fe_dep_repr_C PF02742.15 AIM21419.1 - 2.9e-13 49.7 0.8 6.2e-13 48.6 0.8 1.5 1 0 0 1 1 1 1 Iron dependent repressor, metal binding and dimerisation domain Fe_dep_repress PF01325.19 AIM21419.1 - 1.9e-11 43.9 0.0 3.4e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain MarR_2 PF12802.7 AIM21419.1 - 9.5e-07 28.6 0.2 1.8e-06 27.8 0.2 1.5 1 0 0 1 1 1 1 MarR family GntR PF00392.21 AIM21419.1 - 3.1e-05 23.5 0.0 7.8e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_11 PF08279.12 AIM21419.1 - 5.5e-05 23.0 0.1 0.00011 22.1 0.0 1.5 2 0 0 2 2 1 1 HTH domain Rrf2 PF02082.20 AIM21419.1 - 0.00016 22.0 0.0 0.00039 20.7 0.0 1.6 1 1 1 2 2 2 1 Transcriptional regulator HTH_45 PF14947.6 AIM21419.1 - 0.0003 20.7 0.0 0.00048 20.1 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix TrmB PF01978.19 AIM21419.1 - 0.00037 20.3 0.0 0.00058 19.7 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.6 AIM21419.1 - 0.00057 19.8 0.1 0.0068 16.4 0.0 2.5 1 1 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_24 PF13412.6 AIM21419.1 - 0.0012 18.3 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 AIM21419.1 - 0.0012 18.6 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 AIM21419.1 - 0.0013 18.8 0.0 0.0031 17.5 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_27 PF13463.6 AIM21419.1 - 0.0014 19.1 0.0 0.0024 18.3 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain DUF5596 PF18082.1 AIM21419.1 - 0.0017 18.1 0.1 0.004 17.0 0.0 1.5 2 0 0 2 2 1 1 Domain of unknown function (DUF5596) HTH_DeoR PF08220.12 AIM21419.1 - 0.0024 17.6 0.0 0.0054 16.5 0.0 1.6 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain MarR PF01047.22 AIM21419.1 - 0.0059 16.5 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_23 PF13384.6 AIM21419.1 - 0.0064 16.3 0.4 0.029 14.2 0.1 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_IclR PF09339.10 AIM21419.1 - 0.0072 16.1 0.1 0.014 15.1 0.1 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_AsnC-type PF13404.6 AIM21419.1 - 0.015 15.1 0.1 0.036 13.9 0.1 1.6 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HemN_C PF06969.16 AIM21419.1 - 0.017 15.1 0.0 0.088 12.9 0.0 2.1 2 1 0 2 2 2 0 HemN C-terminal domain HTH_36 PF13730.6 AIM21419.1 - 0.025 14.5 0.0 0.039 13.9 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_CodY PF08222.11 AIM21419.1 - 0.029 13.9 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 CodY helix-turn-helix domain HTH_1 PF00126.27 AIM21419.1 - 0.063 13.2 0.0 0.22 11.5 0.0 2.0 1 1 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family FtsK_gamma PF09397.10 AIM21419.1 - 0.073 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Ftsk gamma domain Nramp PF01566.18 AIM21420.1 - 4.1e-124 414.2 31.0 6.1e-124 413.6 31.0 1.2 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein DUF3638 PF12340.8 AIM21420.1 - 0.17 11.2 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) LysR_substrate PF03466.20 AIM21421.1 - 2.3e-38 131.7 2.5 2.8e-38 131.4 2.5 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM21421.1 - 5.8e-10 39.0 0.1 1.2e-09 38.0 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family SnoaL_3 PF13474.6 AIM21422.1 - 2.1e-07 31.2 0.1 3e-07 30.7 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 AIM21422.1 - 8.7e-07 29.3 0.0 1.5e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 AIM21422.1 - 9.3e-06 26.2 0.0 1.3e-05 25.8 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain Lumazine_bd_2 PF12893.7 AIM21422.1 - 2.7e-05 24.8 0.8 0.00061 20.5 0.8 2.1 1 1 0 1 1 1 1 Putative lumazine-binding CaMKII_AD PF08332.10 AIM21422.1 - 7.5e-05 22.9 0.4 0.00012 22.2 0.4 1.4 1 1 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain SnoaL_4 PF13577.6 AIM21422.1 - 0.0002 21.5 0.3 0.00051 20.2 0.3 1.6 1 1 0 1 1 1 1 SnoaL-like domain NTF2 PF02136.20 AIM21422.1 - 0.00047 20.7 0.5 0.00085 19.9 0.5 1.5 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4101 PF13355.6 AIM21422.1 - 0.00065 20.1 0.8 0.00091 19.7 0.6 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4101) SnoaL PF07366.12 AIM21422.1 - 0.0052 16.6 0.0 0.0074 16.1 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase TraE PF05309.11 AIM21422.1 - 0.018 14.5 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 TraE protein YbgS PF13985.6 AIM21422.1 - 0.18 12.1 1.0 0.24 11.7 0.8 1.4 1 1 0 1 1 1 0 YbgS-like protein adh_short_C2 PF13561.6 AIM21423.1 - 6.4e-53 179.7 0.0 7.9e-53 179.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AIM21423.1 - 3.8e-43 147.2 0.0 4.6e-43 147.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AIM21423.1 - 5.7e-12 45.9 0.1 9.5e-12 45.2 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AIM21423.1 - 0.009 15.5 0.0 0.018 14.5 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 AIM21423.1 - 0.013 14.9 0.0 0.017 14.5 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) HxlR PF01638.17 AIM21424.1 - 1.2e-26 92.4 0.1 1.5e-26 92.0 0.1 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix PadR PF03551.14 AIM21424.1 - 0.036 14.0 0.0 0.059 13.3 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family HTH_20 PF12840.7 AIM21424.1 - 0.079 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain SBP_bac_3 PF00497.20 AIM21425.1 - 1.7e-35 122.5 0.0 2.4e-35 122.0 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 DUF2620 PF10941.8 AIM21425.1 - 0.06 13.5 0.1 0.095 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF2620 DUF2226 PF09987.9 AIM21425.1 - 0.15 11.4 0.1 0.22 10.9 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2226) HIT PF01230.23 AIM21426.1 - 1.6e-30 105.7 0.2 1.8e-30 105.5 0.2 1.0 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 AIM21426.1 - 6.7e-23 81.3 0.0 7.1e-23 81.3 0.0 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF1425 PF07233.12 AIM21427.1 - 7.5e-25 86.7 0.0 9e-25 86.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1425) FIST PF08495.10 AIM21427.1 - 0.081 12.9 0.0 0.4 10.7 0.0 1.8 1 1 1 2 2 2 0 FIST N domain MAGP PF05507.11 AIM21427.1 - 0.21 12.0 0.0 0.3 11.5 0.0 1.3 1 0 0 1 1 1 0 Microfibril-associated glycoprotein (MAGP) LpoB PF13036.6 AIM21428.1 - 4.3e-33 114.3 0.0 5.1e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 Peptidoglycan-synthase activator LpoB LPAM_1 PF08139.12 AIM21428.1 - 0.00012 22.3 1.4 0.00012 22.3 1.4 2.0 2 0 0 2 2 2 1 Prokaryotic membrane lipoprotein lipid attachment site APH PF01636.23 AIM21429.1 - 2.5e-14 53.8 11.5 2.5e-14 53.8 11.5 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 AIM21429.1 - 3.4e-09 36.6 0.0 1.6e-06 27.9 0.0 2.1 1 1 1 2 2 2 2 Choline/ethanolamine kinase Glyco_hydro_3 PF00933.21 AIM21430.1 - 6.8e-99 331.2 0.0 8.5e-99 330.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain FMN_dh PF01070.18 AIM21430.1 - 0.04 12.9 0.0 2.7 6.9 0.0 2.2 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Acetyltransf_5 PF13444.6 AIM21430.1 - 0.071 13.8 0.0 0.15 12.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain UPF0227 PF05728.12 AIM21431.1 - 1.1e-70 237.5 0.0 1.2e-70 237.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Pyr_redox_2 PF07992.14 AIM21432.1 - 1.5e-65 221.4 0.0 1.7e-65 221.2 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AIM21432.1 - 3.5e-17 62.7 2.1 1.3e-10 41.7 0.5 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AIM21432.1 - 4.3e-07 29.8 5.9 0.0047 16.5 0.0 3.4 3 1 0 4 4 4 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 AIM21432.1 - 7.3e-05 22.8 1.4 0.026 14.5 0.0 2.8 3 1 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 AIM21432.1 - 0.00027 20.3 0.0 0.08 12.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 AIM21432.1 - 0.00037 19.8 0.0 0.65 9.1 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 AIM21432.1 - 0.0011 19.2 1.2 0.19 12.0 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 AIM21432.1 - 0.0021 17.2 0.4 0.6 9.1 0.0 2.7 2 0 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.14 AIM21432.1 - 0.0065 15.2 0.1 0.77 8.4 0.0 3.3 4 0 0 4 4 4 1 HI0933-like protein Trp_halogenase PF04820.14 AIM21432.1 - 0.021 13.7 1.4 0.32 9.8 0.1 2.9 3 1 0 3 3 3 0 Tryptophan halogenase ThiF PF00899.21 AIM21432.1 - 0.032 13.6 0.1 2.8 7.2 0.0 2.8 3 0 0 3 3 3 0 ThiF family FAD_binding_3 PF01494.19 AIM21432.1 - 0.038 13.2 0.5 5 6.3 0.1 2.4 2 0 0 2 2 2 0 FAD binding domain ApbA PF02558.16 AIM21432.1 - 0.04 13.6 1.5 2.9 7.5 0.1 2.6 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA Gamma_PGA_hydro PF05908.11 AIM21432.1 - 0.055 12.9 0.2 0.36 10.2 0.0 2.1 2 0 0 2 2 2 0 Poly-gamma-glutamate hydrolase TrkA_N PF02254.18 AIM21432.1 - 0.17 12.1 0.1 12 6.2 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain Rick_17kDa_Anti PF05433.15 AIM21433.1 - 6e-11 42.0 17.4 6e-11 42.0 17.4 2.0 2 0 0 2 2 2 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 AIM21433.1 - 6.3e-05 22.9 16.2 6.3e-05 22.9 16.2 2.4 2 0 0 2 2 2 1 Glycine zipper Gly-zipper_YMGG PF13441.6 AIM21433.1 - 0.00017 21.2 15.9 0.00017 21.2 15.9 2.2 2 0 0 2 2 2 1 YMGG-like Gly-zipper Chlam_OMP6 PF03504.13 AIM21433.1 - 0.13 12.6 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Chlamydia cysteine-rich outer membrane protein 6 TraT PF05818.12 AIM21433.1 - 5.7 6.6 8.6 0.15 11.8 2.5 1.5 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein DUF533 PF04391.12 AIM21433.1 - 7.7 6.0 6.8 8.1 6.0 2.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF533) Rrf2 PF02082.20 AIM21434.1 - 2.7e-13 50.0 0.0 4.9e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulator MethyTransf_Reg PF10119.9 AIM21434.1 - 0.05 14.3 0.2 0.077 13.7 0.2 1.3 1 0 0 1 1 1 0 Predicted methyltransferase regulatory domain ACR_tran PF00873.19 AIM21435.1 - 0 1139.2 9.5 0 1139.0 9.5 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AIM21435.1 - 1.1e-08 34.4 14.8 1.1e-08 34.4 14.8 2.6 2 0 0 2 2 2 2 MMPL family SecD_SecF PF02355.16 AIM21435.1 - 0.00051 19.5 13.8 0.00051 19.5 13.8 2.4 2 0 0 2 2 2 1 Protein export membrane protein DUF561 PF04481.12 AIM21435.1 - 0.051 12.7 0.6 0.12 11.5 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF561) Patched PF02460.18 AIM21435.1 - 2.9 5.9 13.5 4.2 5.3 13.5 1.2 1 0 0 1 1 1 0 Patched family LMBR1 PF04791.16 AIM21435.1 - 3.7 6.3 11.4 0.044 12.7 1.8 2.4 3 0 0 3 3 3 0 LMBR1-like membrane protein MASE5 PF17178.4 AIM21435.1 - 6.2 6.6 14.9 0.056 13.3 4.7 2.3 2 0 0 2 2 2 0 Membrane-associated sensor HlyD_D23 PF16576.5 AIM21436.1 - 1.4e-19 70.2 1.5 2.5e-19 69.4 1.5 1.4 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 AIM21436.1 - 1.8e-16 59.7 4.8 6.8e-16 57.8 0.2 2.9 3 0 0 3 3 3 1 Biotin-lipoyl like HlyD_3 PF13437.6 AIM21436.1 - 1.8e-08 35.1 0.4 0.001 19.8 0.0 2.6 2 0 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl PF00364.22 AIM21436.1 - 0.0034 17.2 0.0 0.046 13.6 0.0 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme Peptidase_M23 PF01551.22 AIM21436.1 - 0.0083 16.3 0.1 0.53 10.5 0.0 2.4 2 0 0 2 2 2 1 Peptidase family M23 HlyD_2 PF12700.7 AIM21436.1 - 0.032 13.0 0.2 0.45 9.2 0.0 2.1 2 0 0 2 2 2 0 HlyD family secretion protein OEP PF02321.18 AIM21436.1 - 0.45 10.3 12.1 0.76 9.5 12.1 1.4 1 0 0 1 1 1 0 Outer membrane efflux protein HTH_18 PF12833.7 AIM21437.1 - 1.8e-22 79.3 0.1 2.3e-22 79.0 0.1 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AIM21437.1 - 1.4e-17 63.3 0.0 2e-08 34.1 0.0 2.1 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family PTR2 PF00854.21 AIM21438.1 - 1.2e-30 106.7 12.1 1.2e-30 106.7 12.1 1.7 2 1 0 2 2 2 1 POT family MFS_1 PF07690.16 AIM21438.1 - 6.8e-20 71.3 64.3 1.6e-12 47.0 33.8 3.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM192 PF14802.6 AIM21438.1 - 0.059 12.5 3.0 1.8 7.6 0.3 3.0 2 1 1 3 3 3 0 TMEM192 family DUF5313 PF17240.2 AIM21438.1 - 0.22 12.0 2.2 0.45 10.9 2.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5313) Sre PF03125.18 AIM21438.1 - 1.4 8.0 6.5 1.1 8.3 3.0 2.5 1 1 0 2 2 2 0 C. elegans Sre G protein-coupled chemoreceptor 2-Hacid_dh_C PF02826.19 AIM21439.1 - 5.8e-46 156.1 0.0 7.9e-46 155.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 AIM21439.1 - 6.3e-07 29.7 0.0 9.2e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 AIM21439.1 - 8e-05 22.7 0.0 0.00016 21.7 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 AIM21439.1 - 0.0061 16.5 0.1 0.0095 15.8 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 AIM21439.1 - 0.0071 16.9 0.1 0.017 15.7 0.1 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 AIM21439.1 - 0.041 13.5 0.1 0.079 12.6 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 AIM21439.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ELM2 PF01448.24 AIM21439.1 - 0.16 12.7 2.4 0.29 11.9 0.4 2.1 2 0 0 2 2 2 0 ELM2 domain PHP PF02811.19 AIM21440.1 - 4.4e-08 33.6 0.0 9.8e-08 32.5 0.1 1.4 1 1 0 1 1 1 1 PHP domain Nitrate_red_del PF02613.15 AIM21441.1 - 8.2e-12 45.3 2.5 9e-12 45.2 0.8 1.8 1 1 1 2 2 2 1 Nitrate reductase delta subunit DUF533 PF04391.12 AIM21442.1 - 4.6e-52 176.2 1.2 5.8e-52 175.9 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF533) TerB PF05099.13 AIM21442.1 - 0.0021 18.0 1.7 0.015 15.3 0.5 2.1 1 1 1 2 2 2 1 Tellurite resistance protein TerB DUF1844 PF08899.11 AIM21442.1 - 0.16 12.3 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1844) YtxH PF12732.7 AIM21442.1 - 1 10.0 4.8 0.92 10.1 2.5 2.3 2 1 0 2 2 2 0 YtxH-like protein Peptidase_S9_N PF02897.15 AIM21443.1 - 1.3e-103 347.1 7.1 1.6e-103 346.7 7.1 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 AIM21443.1 - 6.3e-70 235.0 0.2 1.1e-69 234.2 0.2 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 AIM21443.1 - 0.0013 18.6 0.0 0.0028 17.6 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AIM21443.1 - 0.0023 17.3 0.1 0.004 16.5 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AIM21443.1 - 0.036 14.6 0.2 0.25 11.9 0.0 2.4 1 1 0 2 2 2 0 Alpha/beta hydrolase family AXE1 PF05448.12 AIM21443.1 - 0.043 12.5 0.0 0.083 11.5 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) RNase_T PF00929.24 AIM21444.1 - 3.6e-11 43.9 0.0 6.9e-10 39.7 0.0 2.2 1 1 0 1 1 1 1 Exonuclease CN_hydrolase PF00795.22 AIM21445.1 - 1.1e-29 103.5 2.7 1.4e-29 103.3 2.7 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase zf-dskA_traR PF01258.17 AIM21446.1 - 5.7e-09 35.8 0.1 1e-08 35.0 0.1 1.4 1 0 0 1 1 1 1 Prokaryotic dksA/traR C4-type zinc finger SPT16 PF08644.11 AIM21446.1 - 0.15 12.3 0.5 0.22 11.7 0.5 1.5 1 1 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) DUF4411 PF14367.6 AIM21446.1 - 0.18 11.7 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4411) Abhydrolase_1 PF00561.20 AIM21447.1 - 2.1e-32 112.8 0.1 4e-32 111.9 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AIM21447.1 - 1.2e-13 50.9 0.1 5.4e-09 35.7 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AIM21447.1 - 2e-11 45.0 5.2 3.1e-11 44.3 5.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 AIM21447.1 - 0.048 13.5 0.1 0.16 11.9 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase Peptidase_S28 PF05577.12 AIM21447.1 - 0.094 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Abhydrolase_4 PF08386.10 AIM21447.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Ndr PF03096.14 AIM21447.1 - 0.2 10.3 0.0 0.4 9.4 0.0 1.4 1 1 0 1 1 1 0 Ndr family DNA_pol3_theta PF06440.11 AIM21448.1 - 3.5e-40 135.5 1.0 3.8e-40 135.4 1.0 1.0 1 0 0 1 1 1 1 DNA polymerase III, theta subunit DUF3283 PF11686.8 AIM21448.1 - 0.042 13.7 0.0 0.065 13.1 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3283) Ferritin PF00210.24 AIM21449.1 - 6e-40 136.5 3.7 6.9e-40 136.3 3.7 1.0 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 AIM21449.1 - 0.04 14.3 2.7 0.15 12.5 2.7 1.9 1 1 0 1 1 1 0 Rubrerythrin CopC PF04234.12 AIM21450.1 - 3.1e-24 85.8 0.3 3.6e-24 85.6 0.3 1.1 1 0 0 1 1 1 1 CopC domain DUF3324 PF11797.8 AIM21450.1 - 0.0057 16.6 0.0 0.0082 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function C-terminal (DUF3324) MG2 PF01835.19 AIM21450.1 - 0.012 16.1 0.0 0.018 15.4 0.0 1.3 1 0 0 1 1 1 0 MG2 domain FlgD_ig PF13860.6 AIM21450.1 - 0.013 15.4 0.8 0.023 14.6 0.8 1.5 1 1 0 1 1 1 0 FlgD Ig-like domain Big_5 PF13205.6 AIM21450.1 - 0.035 14.8 0.1 0.048 14.4 0.1 1.2 1 0 0 1 1 1 0 Bacterial Ig-like domain JHBP PF06585.11 AIM21450.1 - 0.078 12.1 0.0 0.095 11.9 0.0 1.1 1 0 0 1 1 1 0 Haemolymph juvenile hormone binding protein (JHBP) CopD PF05425.13 AIM21451.1 - 1.9e-17 63.6 14.0 1.9e-17 63.6 14.0 3.3 2 1 1 3 3 3 1 Copper resistance protein D DUF962 PF06127.11 AIM21451.1 - 0.017 15.2 0.3 0.35 11.0 0.0 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF962) DUF2511 PF10709.9 AIM21452.1 - 1.8e-41 140.3 0.0 2.2e-41 140.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2511) TctB PF07331.11 AIM21454.1 - 0.046 14.0 2.6 0.054 13.8 2.6 1.0 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family Peptidase_U4 PF03419.13 AIM21457.1 - 0.05 12.9 1.6 0.056 12.7 1.6 1.0 1 0 0 1 1 1 0 Sporulation factor SpoIIGA DUF4377 PF14302.6 AIM21459.1 - 4.2e-29 100.4 0.0 5.6e-29 100.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4377) LPAM_1 PF08139.12 AIM21459.1 - 0.024 15.1 2.3 0.045 14.3 2.3 1.4 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site DUF1772 PF08592.11 AIM21460.1 - 0.14 12.5 4.5 0.24 11.7 4.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) DUF4225 PF13988.6 AIM21461.1 - 2.5e-48 163.7 0.1 3e-48 163.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4225) DUF4220 PF13968.6 AIM21461.1 - 0.058 12.8 0.0 0.089 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Enoyl_reductase PF12241.8 AIM21462.1 - 1.1e-115 385.0 0.6 1.3e-115 384.7 0.6 1.1 1 0 0 1 1 1 1 Trans-2-enoyl-CoA reductase catalytic region Eno-Rase_NADH_b PF12242.8 AIM21462.1 - 5.8e-40 134.9 0.4 1.4e-39 133.7 0.4 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Eno-Rase_FAD_bd PF07055.12 AIM21462.1 - 1.3e-29 102.3 1.4 2.4e-29 101.5 1.4 1.4 1 0 0 1 1 1 1 Enoyl reductase FAD binding domain DUF2975 PF11188.8 AIM21463.1 - 2.7e-09 37.0 4.1 2.7e-09 37.0 4.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2975) HTH_26 PF13443.6 AIM21464.1 - 1.3e-24 86.4 0.3 1.4e-24 86.3 0.3 1.0 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_3 PF01381.22 AIM21464.1 - 3e-07 30.4 0.0 3.7e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_37 PF13744.6 AIM21464.1 - 2.3e-05 24.3 0.2 2.4e-05 24.2 0.2 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 AIM21464.1 - 8.2e-05 22.5 0.0 0.0001 22.2 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 AIM21464.1 - 0.00013 22.3 0.0 0.00015 22.0 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain YdaS_antitoxin PF15943.5 AIM21464.1 - 0.038 13.9 0.0 0.045 13.6 0.0 1.2 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_10 PF04967.12 AIM21464.1 - 0.056 13.3 0.0 0.083 12.7 0.0 1.3 1 0 0 1 1 1 0 HTH DNA binding domain TipAS PF07739.13 AIM21465.1 - 0.17 12.4 0.1 0.27 11.8 0.1 1.4 1 1 0 1 1 1 0 TipAS antibiotic-recognition domain DUF4200 PF13863.6 AIM21467.1 - 0.011 16.1 7.1 0.014 15.8 7.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Menin PF05053.13 AIM21467.1 - 0.026 12.9 0.4 0.027 12.9 0.4 1.0 1 0 0 1 1 1 0 Menin Imm35 PF15567.6 AIM21467.1 - 0.041 14.0 0.1 0.079 13.1 0.1 1.5 1 0 0 1 1 1 0 Immunity protein 35 Peptidase_S49_N PF08496.10 AIM21467.1 - 0.13 12.4 2.3 0.13 12.3 2.3 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF1801 PF08818.11 AIM21467.1 - 0.16 12.5 1.5 1.4 9.5 0.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DU1801) Response_reg PF00072.24 AIM21468.1 - 1.1e-21 77.1 0.0 1.6e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain CitT PF12431.8 AIM21468.1 - 0.00045 20.5 0.2 0.00087 19.6 0.2 1.5 1 0 0 1 1 1 1 Transcriptional regulator Rrf2 PF02082.20 AIM21468.1 - 0.024 15.0 0.0 0.061 13.7 0.0 1.7 1 1 0 1 1 1 0 Transcriptional regulator FaeA PF04703.12 AIM21468.1 - 0.059 13.8 0.0 0.3 11.5 0.0 2.1 2 0 0 2 2 2 0 FaeA-like protein HTH_11 PF08279.12 AIM21468.1 - 0.12 12.3 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 HTH domain HTH_DeoR PF08220.12 AIM21468.1 - 0.13 12.1 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain sCache_3_2 PF17203.4 AIM21469.1 - 3.1e-21 76.0 1.0 2.1e-19 70.1 0.9 2.4 2 0 0 2 2 2 1 Single cache domain 3 HATPase_c PF02518.26 AIM21469.1 - 1.1e-16 61.3 0.1 2.7e-16 60.1 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPOB_a PF14689.6 AIM21469.1 - 1.2e-10 40.9 1.6 2.5e-10 39.9 1.6 1.5 1 0 0 1 1 1 1 Sensor_kinase_SpoOB-type, alpha-helical domain dCache_1 PF02743.18 AIM21469.1 - 5.5e-10 39.5 0.0 4.5e-05 23.4 0.0 2.5 2 0 0 2 2 2 2 Cache domain HATPase_c_5 PF14501.6 AIM21469.1 - 9.1e-09 35.1 0.0 1.1e-07 31.6 0.0 2.3 2 0 0 2 2 2 1 GHKL domain PAS PF00989.25 AIM21469.1 - 2.4e-07 30.7 0.1 1.9e-05 24.6 0.0 2.8 2 1 0 2 2 2 1 PAS fold HATPase_c_2 PF13581.6 AIM21469.1 - 0.00076 19.4 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 AIM21469.1 - 0.0047 16.8 0.0 0.0086 15.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_4 PF08448.10 AIM21469.1 - 0.0057 16.9 0.1 0.14 12.4 0.0 2.9 2 1 0 2 2 2 1 PAS fold sCache_3_3 PF17202.4 AIM21469.1 - 0.0085 16.5 0.0 7.6 7.0 0.0 2.6 2 0 0 2 2 2 2 Single cache domain 3 PAS_8 PF13188.7 AIM21469.1 - 0.0095 16.0 0.0 0.025 14.6 0.0 1.7 1 0 0 1 1 1 1 PAS domain DeoC PF01791.9 AIM21470.1 - 4.3e-40 137.8 0.0 5.1e-40 137.6 0.0 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase Peripla_BP_4 PF13407.6 AIM21471.1 - 7.8e-61 205.9 11.4 9.2e-61 205.7 11.4 1.0 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 AIM21471.1 - 3.3e-15 56.2 1.6 4.3e-15 55.9 1.6 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_3 PF13377.6 AIM21471.1 - 5.1e-10 39.9 0.0 1e-09 38.9 0.0 1.5 1 1 0 1 1 1 1 Periplasmic binding protein-like domain PucR PF07905.11 AIM21471.1 - 0.0019 18.4 0.1 0.21 11.9 0.0 2.5 2 1 0 2 2 2 1 Purine catabolism regulatory protein-like family DUF4848 PF16140.5 AIM21471.1 - 0.023 14.3 0.0 0.13 11.8 0.0 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4848) ABC_tran PF00005.27 AIM21472.1 - 7.7e-59 198.1 0.1 3.6e-33 115.0 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 AIM21472.1 - 6.4e-09 36.0 0.2 0.00057 19.8 0.0 2.8 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AIM21472.1 - 3e-05 23.7 0.2 0.00058 19.5 0.1 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AIM21472.1 - 0.00045 20.5 0.8 0.34 11.2 0.1 3.4 2 2 0 2 2 2 1 AAA domain AAA_30 PF13604.6 AIM21472.1 - 0.00074 19.3 0.2 0.31 10.7 0.0 3.2 2 2 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 AIM21472.1 - 0.00076 19.4 0.1 0.011 15.6 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 AIM21472.1 - 0.0013 18.2 3.4 0.12 11.7 0.4 3.6 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 AIM21472.1 - 0.0023 16.8 2.2 14 4.4 0.0 4.0 4 0 0 4 4 4 0 Predicted ATPase of the ABC class MukB PF04310.12 AIM21472.1 - 0.0049 16.7 0.0 0.024 14.4 0.0 2.0 2 0 0 2 2 2 1 MukB N-terminal AAA_23 PF13476.6 AIM21472.1 - 0.0052 17.3 0.0 0.013 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AIM21472.1 - 0.0071 16.7 0.0 0.32 11.4 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_15 PF13175.6 AIM21472.1 - 0.035 13.8 0.0 0.067 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 AIM21472.1 - 0.051 13.6 0.0 0.81 9.8 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AFG1_ATPase PF03969.16 AIM21472.1 - 0.082 11.8 0.2 0.82 8.5 0.0 2.4 3 0 0 3 3 3 0 AFG1-like ATPase DUF2813 PF11398.8 AIM21472.1 - 0.11 11.7 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) BPD_transp_2 PF02653.16 AIM21473.1 - 4.1e-47 160.6 40.0 8.5e-47 159.6 40.0 1.5 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component C_GCAxxG_C_C PF09719.10 AIM21473.1 - 0.83 10.0 2.2 27 5.1 0.6 2.3 2 0 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) Peripla_BP_4 PF13407.6 AIM21474.1 - 1.2e-54 185.6 14.4 1.4e-54 185.4 14.4 1.0 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 AIM21474.1 - 1e-16 61.2 2.9 1.2e-16 60.9 2.9 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_6 PF13458.6 AIM21474.1 - 3.2e-07 30.3 6.3 4.6e-07 29.8 6.3 1.3 1 0 0 1 1 1 1 Periplasmic binding protein Peripla_BP_3 PF13377.6 AIM21474.1 - 0.0017 18.7 0.1 0.0054 17.1 0.0 1.8 1 1 1 2 2 2 1 Periplasmic binding protein-like domain ANF_receptor PF01094.28 AIM21474.1 - 0.071 12.2 0.1 0.19 10.8 0.1 1.5 1 1 0 1 1 1 0 Receptor family ligand binding region PGM_PMM_I PF02878.16 AIM21474.1 - 0.088 12.5 0.2 5.1 6.8 0.0 2.6 1 1 1 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I adh_short_C2 PF13561.6 AIM21475.1 - 1.3e-67 227.8 2.7 1.6e-67 227.5 2.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AIM21475.1 - 2.5e-49 167.4 0.0 3.1e-49 167.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AIM21475.1 - 1.9e-05 24.6 0.2 3.6e-05 23.8 0.2 1.5 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 AIM21475.1 - 0.12 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.18 AIM21475.1 - 0.25 11.2 1.0 0.48 10.3 0.3 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lipoprotein_9 PF03180.14 AIM21476.1 - 2.6e-95 318.0 2.1 3e-95 317.8 2.1 1.0 1 0 0 1 1 1 1 NLPA lipoprotein Phosphonate-bd PF12974.7 AIM21476.1 - 0.012 15.2 0.1 0.025 14.2 0.0 1.5 2 0 0 2 2 2 0 ABC transporter, phosphonate, periplasmic substrate-binding protein Usp PF00582.26 AIM21478.1 - 2.2e-13 51.0 0.0 2.7e-13 50.6 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family Arginase PF00491.21 AIM21478.1 - 0.092 12.2 0.5 0.62 9.5 0.0 1.9 1 1 1 2 2 2 0 Arginase family HTH_20 PF12840.7 AIM21479.1 - 4.4e-16 58.7 0.1 6.3e-16 58.2 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 AIM21479.1 - 1.5e-11 44.0 0.0 2.3e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 AIM21479.1 - 5.1e-05 23.1 0.1 7.6e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 MarR family HTH_34 PF13601.6 AIM21479.1 - 0.0033 17.6 0.0 0.0048 17.1 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain TrmB PF01978.19 AIM21479.1 - 0.0062 16.4 0.0 0.0095 15.8 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.20 AIM21479.1 - 0.033 14.5 0.1 0.051 13.9 0.1 1.4 1 1 0 1 1 1 0 Transcriptional regulator HxlR PF01638.17 AIM21479.1 - 0.14 12.0 0.0 0.21 11.5 0.0 1.3 1 1 0 1 1 1 0 HxlR-like helix-turn-helix HTH_27 PF13463.6 AIM21479.1 - 0.14 12.6 0.0 0.28 11.7 0.0 1.5 1 1 1 2 2 2 0 Winged helix DNA-binding domain AHSA1 PF08327.11 AIM21480.1 - 7.1e-08 32.7 0.0 2.8e-06 27.6 0.1 2.0 1 1 1 2 2 2 2 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.9 AIM21480.1 - 2e-05 24.9 0.1 0.035 14.4 0.2 2.1 1 1 1 2 2 2 2 Polyketide cyclase / dehydrase and lipid transport CLP_protease PF00574.23 AIM21481.1 - 2.4e-77 258.9 0.0 2.8e-77 258.7 0.0 1.0 1 0 0 1 1 1 1 Clp protease HTH_Crp_2 PF13545.6 AIM21482.1 - 3.5e-05 23.7 0.1 8.1e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Rrf2 PF02082.20 AIM21482.1 - 0.0025 18.1 0.1 0.0045 17.3 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulator MarR_2 PF12802.7 AIM21482.1 - 0.0041 17.0 0.1 0.013 15.3 0.0 1.8 2 0 0 2 2 2 1 MarR family HTH_23 PF13384.6 AIM21482.1 - 0.03 14.1 0.0 0.07 13.0 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_6 PF01418.17 AIM21482.1 - 0.05 13.6 0.2 0.097 12.7 0.2 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family MarR PF01047.22 AIM21482.1 - 0.065 13.2 0.0 0.38 10.7 0.0 2.2 2 0 0 2 2 2 0 MarR family CstA PF02554.14 AIM21482.1 - 0.076 11.9 0.8 0.53 9.1 0.2 2.1 2 0 0 2 2 2 0 Carbon starvation protein CstA RepL PF05732.11 AIM21482.1 - 0.098 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) HTH_24 PF13412.6 AIM21482.1 - 0.1 12.2 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_29 PF13551.6 AIM21482.1 - 0.11 12.6 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix PapD_N PF00345.20 AIM21483.1 - 1.3e-34 118.8 0.0 2e-34 118.2 0.0 1.3 1 0 0 1 1 1 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain PapD_C PF02753.17 AIM21483.1 - 6.3e-11 42.5 0.0 1.4e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Pili assembly chaperone PapD, C-terminal domain Fimbrial PF00419.20 AIM21484.1 - 1.2e-25 90.6 5.2 4.2e-25 88.8 4.7 2.0 2 0 0 2 2 2 1 Fimbrial protein Usher PF00577.20 AIM21485.1 - 6.2e-145 484.2 9.8 1.3e-143 479.8 9.8 2.1 1 1 0 1 1 1 1 Outer membrane usher protein PapC_N PF13954.6 AIM21485.1 - 2.5e-35 121.6 0.0 5e-35 120.6 0.0 1.6 1 0 0 1 1 1 1 PapC N-terminal domain PapC_C PF13953.6 AIM21485.1 - 1.5e-22 79.2 0.1 4.4e-22 77.7 0.1 1.9 1 0 0 1 1 1 1 PapC C-terminal domain Big_6 PF17936.1 AIM21485.1 - 0.0091 16.3 0.3 0.03 14.6 0.3 1.9 1 0 0 1 1 1 1 Bacterial Ig domain PapD_N PF00345.20 AIM21486.1 - 2.8e-37 127.4 0.0 4.7e-37 126.7 0.0 1.4 1 0 0 1 1 1 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain PapD_C PF02753.17 AIM21486.1 - 5.9e-13 49.0 0.1 2.2e-12 47.2 0.1 2.0 2 0 0 2 2 2 1 Pili assembly chaperone PapD, C-terminal domain FimA PF16970.5 AIM21487.1 - 3.7e-06 27.2 13.3 1.7e-05 25.0 13.3 2.0 1 1 0 1 1 1 1 Type-1 fimbrial protein, A DUF2574 PF10836.8 AIM21487.1 - 3.8 7.4 8.1 3.4 7.6 1.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2574) GerE PF00196.19 AIM21488.1 - 7.5e-08 31.8 0.1 2.3e-07 30.2 0.0 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family HTH_30 PF13556.6 AIM21488.1 - 0.002 17.9 0.2 0.0051 16.6 0.2 1.7 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_28 PF13518.6 AIM21488.1 - 0.016 15.3 0.4 0.059 13.5 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_1 PF00126.27 AIM21488.1 - 0.018 15.0 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Sigma70_r4_2 PF08281.12 AIM21488.1 - 0.051 13.3 0.1 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 HxlR PF01638.17 AIM21489.1 - 7.4e-19 67.4 0.0 1.2e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 HxlR-like helix-turn-helix HTH_20 PF12840.7 AIM21489.1 - 0.00061 19.8 0.8 0.0014 18.6 0.2 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain TrmB PF01978.19 AIM21489.1 - 0.0018 18.1 0.0 0.0048 16.7 0.0 1.6 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB B-block_TFIIIC PF04182.12 AIM21489.1 - 0.0042 17.2 0.0 0.006 16.7 0.0 1.3 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC MarR_2 PF12802.7 AIM21489.1 - 0.0046 16.8 0.0 0.016 15.1 0.0 1.9 1 1 0 1 1 1 1 MarR family PadR PF03551.14 AIM21489.1 - 0.0092 15.9 0.3 0.016 15.2 0.3 1.3 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_24 PF13412.6 AIM21489.1 - 0.036 13.6 0.0 0.062 12.9 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 AIM21489.1 - 0.069 13.1 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_34 PF13601.6 AIM21489.1 - 0.11 12.7 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain MarR PF01047.22 AIM21489.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_CodY PF08222.11 AIM21489.1 - 0.12 11.9 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 CodY helix-turn-helix domain Tautomerase_3 PF14832.6 AIM21490.1 - 1.4e-50 171.1 0.0 1.6e-50 170.9 0.0 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Tautomerase PF01361.21 AIM21490.1 - 0.0015 18.4 0.0 0.0034 17.3 0.0 1.6 1 1 0 1 1 1 1 Tautomerase enzyme ACR_tran PF00873.19 AIM21491.1 - 1.4e-215 718.2 10.1 1.6e-215 718.0 10.1 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AIM21491.1 - 0.00027 20.0 10.0 0.00027 20.0 10.0 3.0 3 1 0 3 3 3 1 MMPL family SecD_SecF PF02355.16 AIM21491.1 - 0.016 14.6 16.8 0.53 9.6 2.4 2.6 2 0 0 2 2 2 0 Protein export membrane protein HlyD_3 PF13437.6 AIM21492.1 - 1.6e-15 57.7 0.9 4.7e-10 40.1 0.0 3.1 2 1 0 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 AIM21492.1 - 1.7e-15 56.8 4.1 4.6e-15 55.4 4.1 1.7 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 AIM21492.1 - 8e-07 28.8 0.1 3.4e-06 26.8 0.1 2.1 1 0 0 1 1 1 1 Biotin-lipoyl like HlyD_2 PF12700.7 AIM21492.1 - 0.0023 16.7 0.1 1.4 7.6 0.0 2.7 2 1 1 3 3 3 2 HlyD family secretion protein Biotin_lipoyl PF00364.22 AIM21492.1 - 0.0094 15.8 0.0 0.066 13.1 0.0 2.5 3 0 0 3 3 3 1 Biotin-requiring enzyme TetR_N PF00440.23 AIM21493.1 - 8.2e-14 51.1 0.8 2.1e-13 49.8 0.2 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_33 PF13305.6 AIM21493.1 - 0.00017 22.3 0.5 0.00045 20.9 0.0 1.9 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain Ribosomal_S3_C PF00189.20 AIM21493.1 - 0.025 15.1 0.1 0.11 13.0 0.0 2.1 3 0 0 3 3 3 0 Ribosomal protein S3, C-terminal domain HTH_23 PF13384.6 AIM21493.1 - 0.093 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 AIM21493.1 - 0.16 11.4 0.0 0.37 10.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 YchF-GTPase_C PF06071.13 AIM21494.1 - 2.3e-40 136.6 0.2 4.8e-40 135.6 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 AIM21494.1 - 4.9e-22 78.2 0.0 1.5e-21 76.6 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AIM21494.1 - 7.2e-09 35.4 0.0 3.1e-08 33.3 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B TGS PF02824.21 AIM21494.1 - 0.024 14.7 1.3 0.16 12.0 0.2 2.6 2 1 0 2 2 2 0 TGS domain Dynamin_N PF00350.23 AIM21494.1 - 0.079 13.0 0.2 3.4 7.7 0.2 3.0 1 1 0 1 1 1 0 Dynamin family AAA_18 PF13238.6 AIM21494.1 - 0.13 12.8 0.1 0.76 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain Sulfate_transp PF00916.20 AIM21495.1 - 4.9e-48 163.8 38.4 4.8e-29 101.3 5.9 2.5 2 1 1 3 3 3 2 Sulfate permease family STAS PF01740.21 AIM21495.1 - 3.3e-10 39.6 0.0 6e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 AIM21495.1 - 2.1e-08 34.4 0.1 6e-08 32.9 0.1 1.8 1 0 0 1 1 1 1 STAS domain Spore_YabQ PF09578.10 AIM21495.1 - 0.003 17.7 1.2 0.028 14.6 1.2 2.7 1 1 0 1 1 1 1 Spore cortex protein YabQ (Spore_YabQ) HHV6-IE PF03753.13 AIM21495.1 - 0.49 7.8 0.9 4 4.8 0.3 1.9 1 1 1 2 2 2 0 Human herpesvirus 6 immediate early protein Pept_tRNA_hydro PF01195.19 AIM21496.1 - 6.1e-55 185.8 0.0 7.1e-55 185.6 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase DUF2583 PF10762.9 AIM21497.1 - 2.5e-43 146.4 1.1 2.8e-43 146.3 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2583) Pribosyltran_N PF13793.6 AIM21498.1 - 2e-50 169.6 0.1 2e-49 166.4 0.0 2.3 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 AIM21498.1 - 1.2e-30 107.0 0.6 2.4e-30 105.9 0.4 1.6 1 1 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 AIM21498.1 - 6.1e-20 71.3 1.9 9.4e-20 70.7 0.5 2.0 3 0 0 3 3 3 1 Phosphoribosyl transferase domain UPRTase PF14681.6 AIM21498.1 - 0.0011 18.4 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 AIM21498.1 - 0.068 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase GHMP_kinases_N PF00288.26 AIM21499.1 - 2e-10 40.8 0.1 3.5e-10 40.0 0.1 1.4 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 AIM21499.1 - 2.1e-06 28.0 0.0 3.9e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 GHMP kinases C terminal LolB PF03550.14 AIM21500.1 - 1.3e-47 161.7 2.6 1.6e-47 161.4 2.6 1.1 1 0 0 1 1 1 1 Outer membrane lipoprotein LolB DUF3261 PF11659.8 AIM21500.1 - 5.8e-05 23.0 1.1 8.1e-05 22.5 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3261) DUF4292 PF14125.6 AIM21500.1 - 9.6e-05 22.2 0.1 0.0018 18.0 0.1 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4292) Med26_M PF15694.5 AIM21500.1 - 0.017 15.2 0.0 0.022 14.8 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 26 middle domain GlutR_N PF05201.15 AIM21501.1 - 1.9e-53 180.2 0.0 4.1e-53 179.1 0.0 1.6 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, N-terminal domain Shikimate_DH PF01488.20 AIM21501.1 - 3.2e-48 163.3 0.5 3.2e-48 163.3 0.5 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase GlutR_dimer PF00745.20 AIM21501.1 - 3e-25 88.5 1.5 9.8e-25 86.9 1.5 2.0 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, dimerisation domain F420_oxidored PF03807.17 AIM21501.1 - 0.00014 22.4 1.3 0.0006 20.3 0.2 2.7 3 1 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.15 AIM21501.1 - 0.0041 16.1 0.1 0.0077 15.2 0.1 1.4 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family PCRF PF03462.18 AIM21502.1 - 1.6e-75 253.3 1.6 2.1e-75 252.9 0.3 1.7 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 AIM21502.1 - 1.6e-40 137.7 0.2 1.6e-40 137.7 0.2 2.2 3 0 0 3 3 3 1 RF-1 domain ABC_tran_CTD PF16326.5 AIM21502.1 - 0.00092 19.4 0.4 0.00092 19.4 0.4 2.8 2 1 1 3 3 3 1 ABC transporter C-terminal domain Ribosomal_S9 PF00380.19 AIM21502.1 - 0.046 14.3 0.2 0.47 11.0 0.1 2.4 2 0 0 2 2 2 0 Ribosomal protein S9/S16 XhlA PF10779.9 AIM21502.1 - 0.37 11.0 1.5 1.3 9.3 1.5 2.0 1 0 0 1 1 1 0 Haemolysin XhlA Methyltransf_31 PF13847.6 AIM21503.1 - 7.7e-23 81.0 0.0 1.3e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmC_N PF17827.1 AIM21503.1 - 4.5e-19 68.8 1.4 6.9e-19 68.2 0.5 1.9 2 0 0 2 2 1 1 PrmC N-terminal domain MTS PF05175.14 AIM21503.1 - 3e-14 52.9 0.1 5.7e-13 48.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 AIM21503.1 - 1.9e-09 38.1 0.0 6.6e-09 36.4 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 AIM21503.1 - 2.2e-08 33.7 0.0 3.5e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_11 PF08241.12 AIM21503.1 - 1.9e-06 28.4 0.0 1.4e-05 25.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AIM21503.1 - 2.1e-06 27.7 0.0 2.5e-05 24.2 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIM21503.1 - 1.1e-05 26.0 0.0 4.4e-05 24.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 AIM21503.1 - 6.1e-05 22.6 0.0 9.5e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 AIM21503.1 - 0.00022 20.6 0.0 0.0018 17.6 0.0 2.1 2 0 0 2 2 2 1 O-methyltransferase domain Cons_hypoth95 PF03602.15 AIM21503.1 - 0.0012 18.6 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.18 AIM21503.1 - 0.0015 18.3 0.0 0.0023 17.6 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 PCMT PF01135.19 AIM21503.1 - 0.0019 18.0 0.0 0.0026 17.5 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 AIM21503.1 - 0.0031 17.1 0.0 0.0045 16.6 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Ubie_methyltran PF01209.18 AIM21503.1 - 0.008 15.5 0.0 0.024 14.0 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 AIM21503.1 - 0.01 15.8 0.0 0.025 14.5 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.6 AIM21503.1 - 0.014 15.4 0.0 0.021 14.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 AIM21503.1 - 0.024 14.2 0.0 0.036 13.6 0.0 1.1 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_16 PF10294.9 AIM21503.1 - 0.034 13.9 0.0 0.051 13.3 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase SirB PF04247.12 AIM21504.1 - 1.2e-42 144.8 7.6 1.3e-42 144.7 7.6 1.0 1 0 0 1 1 1 1 Invasion gene expression up-regulator, SirB ATP_synt_H PF05493.13 AIM21504.1 - 0.092 13.2 0.2 0.092 13.2 0.2 2.1 3 0 0 3 3 3 0 ATP synthase subunit H MerC PF03203.14 AIM21504.1 - 0.98 9.9 7.4 0.24 11.9 1.9 2.1 1 1 0 2 2 2 0 MerC mercury resistance protein DUF2681 PF10883.8 AIM21504.1 - 8 6.9 6.1 0.78 10.2 0.5 2.1 2 2 1 3 3 3 0 Protein of unknown function (DUF2681) Transglut_core2 PF13369.6 AIM21505.1 - 1.2e-41 141.9 0.0 1.5e-41 141.5 0.0 1.2 1 0 0 1 1 1 1 Transglutaminase-like superfamily TPR_9 PF13371.6 AIM21505.1 - 8.8e-23 80.3 0.0 1.4e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat DAHP_synth_1 PF00793.20 AIM21506.1 - 3.2e-67 226.3 0.0 3.7e-67 226.1 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Sulfate_transp PF00916.20 AIM21507.1 - 2.5e-79 266.8 21.9 2.5e-79 266.8 21.9 1.4 2 0 0 2 2 2 1 Sulfate permease family STAS PF01740.21 AIM21507.1 - 6.3e-09 35.5 0.0 1e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 STAS domain Haem_degrading PF03928.14 AIM21508.1 - 6.4e-31 106.9 0.0 7.5e-31 106.7 0.0 1.1 1 0 0 1 1 1 1 Haem-degrading GGDEF PF00990.21 AIM21509.1 - 5.1e-39 133.6 0.0 6.9e-39 133.2 0.0 1.2 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain TRCF PF03461.15 AIM21510.1 - 3.8e-29 100.9 0.0 2.1e-28 98.5 0.0 2.4 2 0 0 2 2 2 1 TRCF domain CarD_CdnL_TRCF PF02559.16 AIM21510.1 - 4.1e-25 88.3 0.0 1.1e-24 87.0 0.0 1.8 1 0 0 1 1 1 1 CarD-like/TRCF domain UvrB_inter PF17757.1 AIM21510.1 - 1.1e-23 83.2 0.0 2.6e-23 82.0 0.0 1.7 1 0 0 1 1 1 1 UvrB interaction domain Helicase_C PF00271.31 AIM21510.1 - 1.8e-21 76.5 0.9 1.1e-17 64.4 0.3 2.4 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 AIM21510.1 - 6.1e-21 75.0 0.0 1.5e-20 73.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 AIM21510.1 - 3.4e-11 43.4 0.0 6.7e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UB2H PF14814.6 AIM21510.1 - 1.1e-07 31.7 0.2 2.2e-05 24.4 0.0 2.7 2 0 0 2 2 2 1 Bifunctional transglycosylase second domain SNF2_N PF00176.23 AIM21510.1 - 0.0024 16.7 0.0 0.0029 16.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ERCC3_RAD25_C PF16203.5 AIM21510.1 - 0.0026 17.0 0.0 0.0047 16.2 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_30 PF13604.6 AIM21510.1 - 0.016 14.9 0.0 1.5 8.5 0.0 2.7 2 1 0 2 2 2 0 AAA domain Hexapep PF00132.24 AIM21511.1 - 2.7e-15 55.4 20.6 3.4e-10 39.2 5.1 3.3 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AIM21511.1 - 4e-08 32.9 20.4 6.5e-05 22.6 3.0 3.6 3 1 0 4 4 4 3 Hexapeptide repeat of succinyl-transferase FtsX PF02687.21 AIM21512.1 - 2.3e-13 50.4 4.2 2.3e-13 50.4 4.2 3.0 3 0 0 3 3 3 1 FtsX-like permease family MacB_PCD PF12704.7 AIM21512.1 - 4.5e-13 50.0 1.2 4.5e-13 50.0 1.2 1.8 2 0 0 2 2 2 1 MacB-like periplasmic core domain Sigma_reg_N PF13800.6 AIM21512.1 - 0.021 15.1 0.1 0.66 10.3 0.0 2.5 2 0 0 2 2 2 0 Sigma factor regulator N-terminal HPS6 PF15702.5 AIM21512.1 - 0.14 10.1 0.2 0.18 9.8 0.2 1.1 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 6 protein ABC_tran PF00005.27 AIM21513.1 - 5.4e-36 124.1 0.0 7.7e-36 123.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIM21513.1 - 2.8e-06 27.3 0.7 0.073 12.9 0.6 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIM21513.1 - 3.3e-06 26.7 0.1 7.5e-06 25.5 0.1 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AIM21513.1 - 0.00011 21.8 0.1 0.00023 20.8 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AIM21513.1 - 0.00046 20.6 4.1 0.0016 18.8 4.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AIM21513.1 - 0.001 19.0 0.1 0.0017 18.3 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_33 PF13671.6 AIM21513.1 - 0.0017 18.6 0.1 0.0074 16.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AIM21513.1 - 0.0099 16.2 0.9 0.06 13.6 0.9 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AIM21513.1 - 0.016 14.9 0.9 0.047 13.4 0.8 2.0 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 AIM21513.1 - 0.041 14.1 0.2 1.1 9.6 0.2 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit FtsK_SpoIIIE PF01580.18 AIM21513.1 - 0.05 12.9 0.0 0.088 12.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_19 PF13245.6 AIM21513.1 - 0.065 13.6 0.1 1.1 9.6 0.0 2.2 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.17 AIM21513.1 - 0.11 12.6 0.7 0.23 11.5 0.7 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain PRK PF00485.18 AIM21513.1 - 0.13 12.0 0.0 1.7 8.3 0.0 2.1 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.23 AIM21513.1 - 0.15 12.2 0.1 0.31 11.2 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.6 AIM21513.1 - 0.15 12.5 0.0 0.26 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 AIM21513.1 - 0.2 11.6 1.0 0.43 10.5 0.4 1.8 2 0 0 2 2 2 0 NACHT domain MacB_PCD PF12704.7 AIM21514.1 - 3.6e-14 53.6 0.4 3.6e-14 53.6 0.4 2.6 3 0 0 3 3 3 2 MacB-like periplasmic core domain FtsX PF02687.21 AIM21514.1 - 7.5e-14 52.0 14.5 2.3e-13 50.4 3.4 3.3 3 0 0 3 3 3 2 FtsX-like permease family Sensor PF13796.6 AIM21514.1 - 0.001 19.2 10.0 0.7 9.9 4.2 3.2 2 1 0 2 2 2 2 Putative sensor NrfD PF03916.14 AIM21514.1 - 0.1 12.2 12.0 0.099 12.2 6.3 2.1 2 0 0 2 2 2 0 Polysulphide reductase, NrfD ROK PF00480.20 AIM21515.1 - 1.1e-67 228.6 0.0 1.2e-67 228.5 0.0 1.0 1 0 0 1 1 1 1 ROK family Glucokinase PF02685.16 AIM21515.1 - 4.3e-07 29.3 0.1 2e-05 23.8 0.1 2.1 1 1 0 1 1 1 1 Glucokinase Dimerisation PF08100.11 AIM21515.1 - 0.12 12.4 0.0 0.88 9.6 0.0 2.2 2 0 0 2 2 2 0 Dimerisation domain SIR2 PF02146.17 AIM21516.1 - 1.5e-50 171.6 0.0 2.4e-50 170.9 0.0 1.3 1 0 0 1 1 1 1 Sir2 family Glyco_transf_28 PF03033.20 AIM21516.1 - 0.019 15.0 0.0 0.18 11.8 0.0 2.2 2 0 0 2 2 2 0 Glycosyltransferase family 28 N-terminal domain AvrPphF-ORF-2 PF09143.10 AIM21516.1 - 0.16 11.9 0.0 0.34 10.8 0.0 1.6 2 0 0 2 2 2 0 AvrPphF-ORF-2 SBP_bac_8 PF13416.6 AIM21517.1 - 1.6e-40 139.7 1.7 2.1e-40 139.3 1.7 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AIM21517.1 - 1.7e-35 122.6 0.5 2.1e-35 122.3 0.5 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AIM21517.1 - 2.2e-15 57.5 5.1 6.7e-15 55.8 5.1 1.7 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 AIM21517.1 - 3.3e-13 49.9 0.0 4.7e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein Lipoprotein_8 PF02030.15 AIM21517.1 - 3.1e-10 39.4 0.0 4.1e-09 35.7 0.1 2.1 2 0 0 2 2 2 1 Hypothetical lipoprotein (MG045 family) BPD_transp_1 PF00528.22 AIM21518.1 - 3.6e-19 69.2 24.0 1.5e-18 67.2 16.8 2.1 1 1 1 2 2 2 2 Binding-protein-dependent transport system inner membrane component DUF3341 PF11821.8 AIM21518.1 - 2.5 7.7 9.4 4.7 6.8 8.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3341) BPD_transp_1 PF00528.22 AIM21519.1 - 2.4e-19 69.8 10.5 2.4e-19 69.8 10.5 1.8 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 AIM21520.1 - 2.3e-35 122.1 0.0 4.8e-35 121.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter TOBE_2 PF08402.10 AIM21520.1 - 3.2e-09 36.8 0.0 7.9e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 TOBE domain TniB PF05621.11 AIM21520.1 - 3.1e-07 30.0 0.4 0.0088 15.5 0.2 3.2 3 0 0 3 3 3 2 Bacterial TniB protein AAA_22 PF13401.6 AIM21520.1 - 3.5e-06 27.3 0.2 7.5e-05 23.0 0.5 2.6 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.6 AIM21520.1 - 3.6e-06 27.0 0.0 0.034 14.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 AIM21520.1 - 3.2e-05 24.4 0.0 0.0073 16.7 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.19 AIM21520.1 - 5.2e-05 22.8 0.2 0.015 14.8 0.1 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AIM21520.1 - 0.0011 19.4 0.0 0.0042 17.5 0.1 2.0 2 1 0 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 AIM21520.1 - 0.004 17.1 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_28 PF13521.6 AIM21520.1 - 0.0065 16.7 0.1 0.82 9.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain ABC_ATPase PF09818.9 AIM21520.1 - 0.0089 14.9 0.2 0.13 11.1 0.0 2.5 2 1 0 2 2 2 1 Predicted ATPase of the ABC class AAA_14 PF13173.6 AIM21520.1 - 0.012 15.7 0.0 0.15 12.1 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 AIM21520.1 - 0.015 15.0 0.1 0.033 13.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 AIM21520.1 - 0.02 14.8 0.1 0.089 12.7 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase sCache_3_2 PF17203.4 AIM21520.1 - 0.022 14.9 0.0 0.043 13.9 0.0 1.4 1 0 0 1 1 1 0 Single cache domain 3 AAA_18 PF13238.6 AIM21520.1 - 0.022 15.3 0.0 0.065 13.8 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AIM21520.1 - 0.025 14.2 0.5 2.4 7.7 0.1 2.7 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 AIM21520.1 - 0.039 13.9 0.1 0.11 12.4 0.1 1.9 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 AIM21520.1 - 0.078 12.7 0.0 1.7 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 AIM21520.1 - 0.099 13.0 0.1 0.25 11.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AIM21520.1 - 0.11 13.0 2.1 0.16 12.5 0.4 1.9 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 AIM21520.1 - 0.16 11.3 0.9 11 5.3 0.1 2.5 3 0 0 3 3 3 0 KaiC Peptidase_M20 PF01546.28 AIM21521.1 - 2.4e-16 60.1 0.2 4.2e-16 59.3 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AIM21521.1 - 8.6e-13 48.2 0.0 1.6e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M42 PF05343.14 AIM21521.1 - 2.2e-05 23.7 0.0 0.00027 20.0 0.0 2.1 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase Peptidase_M28 PF04389.17 AIM21521.1 - 0.018 14.8 0.1 0.079 12.6 0.1 2.0 2 0 0 2 2 2 0 Peptidase family M28 Peptidase_S74 PF13884.6 AIM21522.1 - 1.1e-11 44.8 0.0 2.4e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Chaperone of endosialidase Pyocin_S PF06958.12 AIM21523.1 - 3.1e-31 108.8 1.2 6.2e-31 107.8 1.2 1.5 1 0 0 1 1 1 1 S-type Pyocin Peptidase_S49_N PF08496.10 AIM21523.1 - 0.89 9.6 4.3 1.5 8.9 4.3 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Borrelia_P83 PF05262.11 AIM21523.1 - 1.1 7.7 7.0 1.5 7.2 7.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Colicin_Pyocin PF01320.18 AIM21524.1 - 1.9e-30 104.8 0.4 2.1e-30 104.6 0.4 1.0 1 0 0 1 1 1 1 Colicin immunity protein / pyocin immunity protein Endonuclease_1 PF04231.13 AIM21524.1 - 0.0087 15.8 0.1 0.0096 15.6 0.1 1.1 1 0 0 1 1 1 1 Endonuclease I Colicin_D PF11429.8 AIM21525.1 - 8.7e-28 96.6 0.6 2.6e-27 95.1 0.4 1.7 2 0 0 2 2 2 1 Colicin D Pyocin_S PF06958.12 AIM21525.1 - 6e-09 36.6 0.1 1e-08 35.8 0.1 1.3 1 0 0 1 1 1 1 S-type Pyocin Phosphodiest PF01663.22 AIM21525.1 - 0.078 12.5 0.0 0.096 12.3 0.0 1.1 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase Colicin_immun PF09204.10 AIM21526.1 - 5.2e-17 62.1 0.3 5.9e-17 62.0 0.3 1.0 1 0 0 1 1 1 1 Bacterial self-protective colicin-like immunity R2K_3 PF14243.6 AIM21527.1 - 2.4e-11 44.0 0.0 9.6e-11 42.1 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain, R2K clade family 3 R2K_2 PF18299.1 AIM21527.1 - 7.9e-06 25.8 0.0 1.9e-05 24.5 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain, R2K clade family 2 Cupin_4 PF08007.12 AIM21528.1 - 1.3e-101 340.3 0.0 1.6e-101 340.0 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_1 PF00190.22 AIM21528.1 - 0.0031 17.1 0.0 0.0049 16.5 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 AIM21528.1 - 0.0052 16.5 0.2 0.22 11.3 0.0 2.5 2 0 0 2 2 2 1 Cupin domain Cupin_8 PF13621.6 AIM21528.1 - 0.11 12.2 0.1 0.37 10.5 0.0 1.8 2 1 0 2 2 2 0 Cupin-like domain TAD2 PF18521.1 AIM21528.1 - 0.17 11.9 3.2 9.3 6.4 0.4 3.0 2 0 0 2 2 2 0 Transactivation domain 2 AraC_binding PF02311.19 AIM21528.1 - 0.21 11.5 2.7 0.36 10.7 0.4 2.6 2 1 0 2 2 2 0 AraC-like ligand binding domain PhoQ_Sensor PF08918.10 AIM21529.1 - 3.5e-80 268.1 0.1 5.7e-80 267.4 0.1 1.3 1 0 0 1 1 1 1 PhoQ Sensor HATPase_c PF02518.26 AIM21529.1 - 1.5e-12 48.0 0.0 2.5e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 AIM21529.1 - 8.4e-06 26.1 0.5 0.00019 21.8 0.1 2.4 2 0 0 2 2 2 1 HAMP domain HATPase_c_5 PF14501.6 AIM21529.1 - 2.2e-05 24.3 0.0 4.2e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 GHKL domain HisKA PF00512.25 AIM21529.1 - 0.0027 17.7 0.1 0.008 16.2 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Baculo_PEP_C PF04513.12 AIM21529.1 - 0.061 13.4 0.5 0.12 12.4 0.5 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Response_reg PF00072.24 AIM21530.1 - 1.1e-25 89.9 0.0 1.9e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AIM21530.1 - 2.2e-20 72.5 0.1 4.3e-20 71.6 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal FleQ PF06490.11 AIM21530.1 - 0.0019 18.5 0.0 0.003 17.9 0.0 1.4 1 0 0 1 1 1 1 Flagellar regulatory protein FleQ ADP_ribosyl_GH PF03747.14 AIM21531.1 - 1.7e-59 202.0 5.0 2.1e-59 201.6 5.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase UTRA PF07702.13 AIM21532.1 - 4.4e-36 123.8 0.2 6.2e-36 123.3 0.2 1.2 1 0 0 1 1 1 1 UTRA domain GntR PF00392.21 AIM21532.1 - 9.4e-16 57.2 0.3 8.6e-15 54.1 0.0 2.6 3 0 0 3 3 3 1 Bacterial regulatory proteins, gntR family HTH_41 PF14502.6 AIM21532.1 - 0.00025 20.7 0.0 0.0073 16.0 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_11 PF08279.12 AIM21532.1 - 0.00047 20.1 0.1 0.0034 17.3 0.0 2.2 2 0 0 2 2 2 1 HTH domain HTH_DeoR PF08220.12 AIM21532.1 - 0.00073 19.2 0.0 0.002 17.9 0.0 1.9 2 0 0 2 2 2 1 DeoR-like helix-turn-helix domain HTH_24 PF13412.6 AIM21532.1 - 0.0045 16.5 0.3 0.12 12.0 0.1 2.5 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 AIM21532.1 - 0.0059 16.5 0.2 0.022 14.7 0.0 2.1 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain Rrf2 PF02082.20 AIM21532.1 - 0.0068 16.7 0.1 0.61 10.5 0.0 2.6 2 0 0 2 2 2 1 Transcriptional regulator HTH_36 PF13730.6 AIM21532.1 - 0.025 14.5 0.1 0.078 12.9 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_CodY PF08222.11 AIM21532.1 - 0.065 12.8 0.3 0.37 10.4 0.0 2.2 2 0 0 2 2 2 0 CodY helix-turn-helix domain HTH_28 PF13518.6 AIM21532.1 - 0.08 13.1 0.2 0.34 11.1 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain UIM PF02809.20 AIM21532.1 - 0.11 12.4 0.9 0.55 10.3 0.9 2.3 1 0 0 1 1 1 0 Ubiquitin interaction motif MarR PF01047.22 AIM21532.1 - 0.11 12.4 0.1 1.8 8.5 0.1 2.4 2 0 0 2 2 2 0 MarR family MarR_2 PF12802.7 AIM21532.1 - 0.15 12.0 1.7 1.1 9.3 0.0 3.0 3 1 0 3 3 3 0 MarR family Aminotran_1_2 PF00155.21 AIM21533.1 - 3.9e-27 95.4 0.0 5.6e-27 94.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II GntR PF00392.21 AIM21533.1 - 2.8e-11 42.9 2.6 4.8e-11 42.1 0.4 2.4 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_Crp_2 PF13545.6 AIM21533.1 - 0.0012 18.7 0.2 0.0053 16.7 0.0 2.1 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain MarR_2 PF12802.7 AIM21533.1 - 0.012 15.4 2.0 0.17 11.8 0.4 3.2 1 1 2 3 3 3 0 MarR family Fe_dep_repress PF01325.19 AIM21533.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Acetyltransf_1 PF00583.25 AIM21534.1 - 1.5e-13 51.0 0.0 1.9e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AIM21534.1 - 1e-05 25.5 0.0 1.3e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AIM21534.1 - 1.4e-05 25.4 0.0 2.3e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AIM21534.1 - 0.00069 19.7 0.1 0.0012 19.0 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AIM21534.1 - 0.0097 15.9 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 AIM21535.1 - 1.7e-13 51.4 0.0 2.8e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AIM21535.1 - 2.4e-05 24.5 0.0 3.4e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Lyase_1 PF00206.20 AIM21536.1 - 5.2e-78 262.6 0.0 6.3e-78 262.3 0.0 1.1 1 0 0 1 1 1 1 Lyase ASL_C PF08328.11 AIM21536.1 - 1.7e-52 176.4 0.1 4.3e-52 175.1 0.0 1.8 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminal DUF489 PF04356.12 AIM21537.1 - 2.4e-77 259.3 0.3 2.8e-77 259.1 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF489) K_trans PF02705.16 AIM21538.1 - 4.1e-208 692.2 19.1 4.7e-208 692.0 19.1 1.0 1 0 0 1 1 1 1 K+ potassium transporter NUDIX PF00293.28 AIM21539.1 - 3.4e-17 62.7 0.2 4.3e-17 62.4 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain LprI PF07007.12 AIM21540.1 - 2.1e-06 28.3 6.5 4e-06 27.4 6.5 1.5 1 1 0 1 1 1 1 Lysozyme inhibitor LprI PseudoU_synth_2 PF00849.22 AIM21541.1 - 2.8e-13 50.3 0.0 4.2e-12 46.4 0.0 2.1 1 1 0 1 1 1 1 RNA pseudouridylate synthase Iso_dh PF00180.20 AIM21542.1 - 1.3e-117 392.9 0.0 1.5e-117 392.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase tRNA_synt_1c_R1 PF04558.15 AIM21542.1 - 0.091 12.8 0.2 0.75 9.8 0.0 2.1 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Usp PF00582.26 AIM21543.1 - 8.2e-27 94.4 0.8 9.4e-27 94.2 0.8 1.0 1 0 0 1 1 1 1 Universal stress protein family DUF903 PF06004.12 AIM21544.1 - 1e-17 63.8 0.6 1.2e-17 63.5 0.6 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF903) LPAM_1 PF08139.12 AIM21544.1 - 0.076 13.5 5.6 0.21 12.1 5.6 1.7 1 1 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site DUF903 PF06004.12 AIM21545.1 - 1.2e-18 66.7 3.9 1.4e-18 66.5 3.9 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF903) TolA PF06519.11 AIM21546.1 - 4.4e-27 94.1 0.0 6.1e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 TolA C-terminal TonB_2 PF13103.6 AIM21546.1 - 2.9e-06 27.4 0.0 4.4e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 TonB C terminal TonB_C PF03544.14 AIM21546.1 - 0.0028 18.1 0.0 0.0044 17.4 0.0 1.3 1 0 0 1 1 1 1 Gram-negative bacterial TonB protein C-terminal DHO_dh PF01180.21 AIM21546.1 - 0.12 11.6 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase MLTD_N PF06474.12 AIM21547.1 - 0.47 10.7 2.6 1.1 9.5 2.6 1.5 1 0 0 1 1 1 0 MltD lipid attachment motif Acetyltransf_1 PF00583.25 AIM21548.1 - 4e-08 33.5 0.1 4.7e-08 33.3 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AIM21548.1 - 5.3e-08 32.9 0.0 6.5e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AIM21548.1 - 3.7e-06 27.3 0.1 5.3e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AIM21548.1 - 0.00011 22.9 0.0 0.00014 22.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 AIM21548.1 - 0.0076 16.0 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ FR47 PF08445.10 AIM21548.1 - 0.042 13.8 0.0 0.06 13.3 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein PTS_EIIC PF02378.18 AIM21549.1 - 0.077 12.0 2.2 0.087 11.8 2.2 1.1 1 0 0 1 1 1 0 Phosphotransferase system, EIIC DUF1230 PF06799.11 AIM21549.1 - 0.2 11.8 1.5 0.21 11.7 1.5 1.1 1 0 0 1 1 1 0 Conserved in the green lineage and diatoms 27 DUF4131 PF13567.6 AIM21549.1 - 0.64 9.6 6.0 0.73 9.5 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Tad PF13400.6 AIM21549.1 - 4.5 7.6 7.9 8.4 6.8 0.6 2.2 1 1 1 2 2 2 0 Putative Flp pilus-assembly TadE/G-like SPT_ssu-like PF11779.8 AIM21549.1 - 5.3 6.7 8.0 0.51 10.0 0.5 2.1 2 0 0 2 2 2 0 Small subunit of serine palmitoyltransferase-like AI-2E_transport PF01594.16 AIM21550.1 - 2.7e-49 168.1 35.8 3.5e-49 167.7 35.8 1.0 1 0 0 1 1 1 1 AI-2E family transporter DUF1980 PF09323.10 AIM21551.1 - 0.18 11.7 0.4 0.19 11.6 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) MFS_1 PF07690.16 AIM21552.1 - 5.4e-34 117.7 63.8 5.9e-30 104.4 50.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 AIM21552.1 - 3.1e-09 36.6 39.5 4.2e-09 36.2 39.5 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 AIM21552.1 - 4.3e-09 35.8 10.3 4.3e-09 35.8 10.3 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 AIM21552.1 - 0.25 9.6 13.7 0.042 12.1 2.9 3.0 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF2000 PF09391.10 AIM21554.1 - 1e-25 90.2 0.0 1.1e-25 90.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2000) Glyco_hydro_42C PF08533.10 AIM21554.1 - 0.032 14.0 0.3 0.075 12.8 0.1 1.8 2 1 0 2 2 2 0 Beta-galactosidase C-terminal domain Peripla_BP_4 PF13407.6 AIM21555.1 - 6e-22 78.5 0.0 8.9e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain LacI PF00356.21 AIM21555.1 - 1.4e-09 37.6 0.5 2.9e-09 36.6 0.5 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family HTH_Tnp_ISL3 PF13542.6 AIM21555.1 - 0.025 14.0 0.2 0.063 12.7 0.2 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 ECH_1 PF00378.20 AIM21555.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase AP_endonuc_2 PF01261.24 AIM21556.1 - 6.4e-30 104.2 0.1 1.4e-29 103.1 0.1 1.6 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel GFO_IDH_MocA PF01408.22 AIM21557.1 - 1.1e-28 100.4 0.0 1.9e-28 99.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 AIM21557.1 - 9.4e-13 48.2 0.0 1.9e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain HIGH_NTase1 PF05636.11 AIM21557.1 - 0.083 12.1 0.1 0.12 11.5 0.1 1.1 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase GFA PF04828.14 AIM21558.1 - 2.8e-07 30.8 0.7 2.8e-07 30.8 0.7 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Pentapeptide PF00805.22 AIM21560.1 - 8e-24 82.9 11.7 0.00012 21.6 0.1 5.4 3 1 2 6 6 6 6 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 AIM21560.1 - 1.9e-22 79.2 3.3 3.3e-09 36.8 0.9 3.5 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 AIM21560.1 - 6.7e-10 39.0 17.6 0.018 15.2 0.3 4.7 3 1 0 3 3 3 3 Pentapeptide repeats (9 copies) LPAM_2 PF13627.6 AIM21561.1 - 1.8 8.5 5.6 3.4 7.6 5.6 1.5 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site CSD PF00313.22 AIM21562.1 - 2e-31 107.6 0.3 2.2e-31 107.5 0.3 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 AIM21562.1 - 0.0035 17.0 0.7 0.0049 16.5 0.7 1.4 1 1 0 1 1 1 1 Ribonuclease B OB domain CusF_Ec PF11604.8 AIM21562.1 - 0.071 13.1 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Copper binding periplasmic protein CusF S1 PF00575.23 AIM21562.1 - 0.14 12.5 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 S1 RNA binding domain Isochorismatase PF00857.20 AIM21563.1 - 5.4e-20 72.3 0.1 9.4e-20 71.5 0.1 1.4 1 1 0 1 1 1 1 Isochorismatase family Usp PF00582.26 AIM21564.1 - 1.2e-13 51.7 0.2 2.6e-13 50.7 0.1 1.6 1 1 1 2 2 2 2 Universal stress protein family adh_short_C2 PF13561.6 AIM21565.1 - 6.1e-68 228.9 4.4 7e-68 228.7 4.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AIM21565.1 - 2.7e-51 173.8 1.6 3.2e-51 173.6 1.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AIM21565.1 - 2e-09 37.6 1.3 2.7e-09 37.2 1.3 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 AIM21565.1 - 0.00034 20.9 0.5 0.00063 20.0 0.5 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 AIM21565.1 - 0.032 14.1 1.5 0.065 13.1 1.1 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 AIM21566.1 - 1.7e-54 185.7 0.4 2e-54 185.5 0.4 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 AIM21566.1 - 6.2e-06 25.7 0.8 9.8e-06 25.0 0.8 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 AIM21566.1 - 1.6e-05 24.3 0.1 2.7e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 AIM21566.1 - 2.3e-05 24.5 0.7 7.7e-05 22.8 0.7 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AIM21566.1 - 0.0002 20.7 0.1 0.00031 20.1 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AIM21566.1 - 0.001 18.3 1.8 0.0016 17.6 1.8 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 AIM21566.1 - 0.002 18.7 0.4 0.004 17.7 0.4 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AIM21566.1 - 0.0067 15.7 1.0 0.3 10.3 0.5 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 AIM21566.1 - 0.013 14.8 0.2 2 7.6 0.2 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase HI0933_like PF03486.14 AIM21566.1 - 0.016 13.9 0.2 0.085 11.5 0.1 1.9 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.12 AIM21566.1 - 0.034 13.2 0.5 2.7 6.9 0.3 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.14 AIM21566.1 - 0.036 13.7 0.9 0.057 13.0 0.9 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 AIM21566.1 - 0.052 14.0 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding GIDA PF01134.22 AIM21566.1 - 0.098 11.7 0.1 0.16 11.1 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 AIM21566.1 - 0.15 11.3 0.3 0.22 10.8 0.3 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 AIM21566.1 - 0.35 10.7 0.5 0.53 10.1 0.5 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Aldedh PF00171.22 AIM21567.1 - 8.2e-169 562.0 0.0 9.3e-169 561.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cupin_2 PF07883.11 AIM21568.1 - 5.4e-17 61.3 0.1 7.9e-17 60.7 0.1 1.3 1 0 0 1 1 1 1 Cupin domain HTH_3 PF01381.22 AIM21568.1 - 4.4e-13 49.1 0.2 6.6e-13 48.5 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 AIM21568.1 - 1.4e-10 41.3 0.1 2.5e-10 40.5 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 AIM21568.1 - 6.8e-09 35.6 0.0 1.2e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain AraC_binding PF02311.19 AIM21568.1 - 8.1e-05 22.5 0.1 0.00016 21.6 0.1 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain MqsA_antitoxin PF15731.5 AIM21568.1 - 0.00014 21.9 0.0 0.00026 21.1 0.0 1.3 1 0 0 1 1 1 1 Antitoxin component of bacterial toxin-antitoxin system, MqsA HTH_37 PF13744.6 AIM21568.1 - 0.00086 19.2 0.1 0.0015 18.5 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 AIM21568.1 - 0.0016 18.8 0.0 0.0051 17.2 0.0 1.8 2 0 0 2 2 2 1 Cro/C1-type HTH DNA-binding domain HTH_25 PF13413.6 AIM21568.1 - 0.0081 16.0 0.1 0.013 15.4 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Cupin_3 PF05899.12 AIM21568.1 - 0.094 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Death PF00531.22 AIM21568.1 - 0.12 12.6 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Death domain Peptidase_C26 PF07722.13 AIM21569.1 - 1e-65 221.6 0.0 1.1e-65 221.4 0.0 1.0 1 0 0 1 1 1 1 Peptidase C26 GATase PF00117.28 AIM21569.1 - 3.5e-13 49.8 0.0 8.4e-13 48.5 0.0 1.6 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Gln-synt_C PF00120.24 AIM21570.1 - 3.4e-103 345.3 0.0 4.1e-103 345.0 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 AIM21570.1 - 0.0049 16.7 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 Glutamine synthetase N-terminal domain AA_permease PF00324.21 AIM21571.1 - 1.2e-37 129.6 31.4 1.5e-37 129.3 31.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 AIM21571.1 - 1e-28 100.4 37.6 1.3e-28 100.1 37.6 1.1 1 0 0 1 1 1 1 Amino acid permease EamA PF00892.20 AIM21572.1 - 1.5e-15 57.6 41.3 7.7e-08 32.6 18.2 2.1 2 0 0 2 2 2 2 EamA-like transporter family Channel_Tsx PF03502.13 AIM21574.1 - 1.1e-81 274.2 18.3 1.2e-81 274.1 18.3 1.0 1 0 0 1 1 1 1 Nucleoside-specific channel-forming protein, Tsx RcnB PF11776.8 AIM21576.1 - 0.00012 22.0 0.1 0.00027 20.9 0.0 1.7 2 0 0 2 2 2 1 Nickel/cobalt transporter regulator YbgS PF13985.6 AIM21576.1 - 0.00098 19.4 0.3 0.0014 18.9 0.3 1.2 1 0 0 1 1 1 1 YbgS-like protein DUF1236 PF06823.12 AIM21576.1 - 0.096 12.6 0.0 0.17 11.8 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1236) CM_2 PF01817.21 AIM21577.1 - 6.7e-10 39.2 2.1 1.7e-09 37.8 0.1 2.2 2 1 0 2 2 2 1 Chorismate mutase type II DUF4880 PF16220.5 AIM21577.1 - 0.037 13.9 0.8 0.037 13.9 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4880) Beta-lactamase PF00144.24 AIM21578.1 - 1.3e-34 119.9 4.6 1.9e-34 119.4 4.6 1.1 1 0 0 1 1 1 1 Beta-lactamase FGase PF05013.12 AIM21579.1 - 1.1e-65 221.9 0.0 1.3e-65 221.7 0.0 1.1 1 0 0 1 1 1 1 N-formylglutamate amidohydrolase Amidohydro_1 PF01979.20 AIM21580.1 - 2.4e-18 66.6 0.3 2.7e-17 63.1 0.3 2.2 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AIM21580.1 - 8e-17 61.9 7.3 2.2e-13 50.5 1.8 2.3 1 1 1 2 2 2 2 Amidohydrolase family UTRA PF07702.13 AIM21581.1 - 9.9e-36 122.7 0.7 1.7e-35 121.9 0.7 1.4 1 0 0 1 1 1 1 UTRA domain GntR PF00392.21 AIM21581.1 - 1.4e-22 79.1 0.1 2.7e-22 78.2 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_DeoR PF08220.12 AIM21581.1 - 5.5e-05 22.8 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain MarR PF01047.22 AIM21581.1 - 0.00024 21.0 0.0 0.00054 19.8 0.0 1.6 1 0 0 1 1 1 1 MarR family HTH_11 PF08279.12 AIM21581.1 - 0.00029 20.7 0.0 0.00088 19.2 0.0 1.8 1 0 0 1 1 1 1 HTH domain HTH_24 PF13412.6 AIM21581.1 - 0.0018 17.8 0.1 0.0039 16.7 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 AIM21581.1 - 0.0024 17.7 0.0 0.0069 16.2 0.0 1.9 1 0 0 1 1 1 1 MarR family DUF2398 PF09661.10 AIM21581.1 - 0.0026 17.1 0.1 0.0044 16.3 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2398) TrmB PF01978.19 AIM21581.1 - 0.0034 17.2 0.1 0.047 13.6 0.0 2.3 1 1 1 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.6 AIM21581.1 - 0.0058 16.6 0.1 0.013 15.4 0.1 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_23 PF13384.6 AIM21581.1 - 0.023 14.5 0.0 0.071 12.9 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain RP-C PF03428.13 AIM21581.1 - 0.041 13.5 0.1 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 Replication protein C N-terminal domain HTH_36 PF13730.6 AIM21581.1 - 0.1 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain RPA_C PF08784.11 AIM21581.1 - 0.14 12.9 0.0 0.45 11.2 0.0 1.9 1 1 1 2 2 2 0 Replication protein A C terminal Sigma70_r3 PF04539.16 AIM21581.1 - 0.17 12.0 0.8 1.6 8.9 0.1 2.6 2 0 0 2 2 2 0 Sigma-70 region 3 HTH_41 PF14502.6 AIM21581.1 - 0.18 11.5 0.0 0.38 10.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HutD PF05962.11 AIM21582.1 - 6.1e-50 169.7 0.0 6.9e-50 169.6 0.0 1.0 1 0 0 1 1 1 1 HutD Peripla_BP_1 PF00532.21 AIM21583.1 - 1.2e-51 175.8 0.0 1.4e-51 175.5 0.0 1.0 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_3 PF13377.6 AIM21583.1 - 2.2e-20 73.6 0.2 4.4e-20 72.7 0.2 1.5 2 0 0 2 2 2 1 Periplasmic binding protein-like domain LacI PF00356.21 AIM21583.1 - 7.6e-17 60.8 0.0 1.3e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 AIM21583.1 - 0.0013 18.3 0.0 0.03 13.9 0.0 2.2 1 1 0 1 1 1 1 Periplasmic binding protein domain HTH_23 PF13384.6 AIM21583.1 - 0.028 14.2 0.0 0.64 9.9 0.0 2.6 2 0 0 2 2 2 0 Homeodomain-like domain B12-binding PF02310.19 AIM21583.1 - 0.037 14.1 0.0 0.36 10.9 0.0 2.5 2 2 0 2 2 2 0 B12 binding domain HTH_3 PF01381.22 AIM21583.1 - 0.076 13.1 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix Glyco_hydro_32N PF00251.20 AIM21584.1 - 3e-100 335.7 0.0 3.6e-100 335.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 AIM21584.1 - 2.4e-22 79.6 0.0 3.4e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_43 PF04616.14 AIM21584.1 - 0.056 12.8 0.1 0.46 9.8 0.1 1.9 1 1 1 2 2 2 0 Glycosyl hydrolases family 43 LacY_symp PF01306.19 AIM21585.1 - 8.9e-136 452.9 24.4 1.1e-135 452.7 24.4 1.0 1 0 0 1 1 1 1 LacY proton/sugar symporter MFS_1_like PF12832.7 AIM21585.1 - 3.7e-21 75.4 24.7 1.2e-19 70.5 24.3 2.3 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 AIM21585.1 - 3e-13 49.4 50.9 1.8e-12 46.9 41.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AIM21586.1 - 2.6e-36 125.5 29.3 3.3e-28 98.7 8.9 2.0 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 AIM21586.1 - 2.2e-29 102.5 50.9 5.2e-19 68.4 31.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DAPG_hydrolase PF18089.1 AIM21587.1 - 2.1e-42 145.2 0.0 3.8e-42 144.4 0.0 1.3 1 1 0 1 1 1 1 DAPG hydrolase PhiG domain TetR_C_7 PF14246.6 AIM21588.1 - 5.3e-12 45.8 0.5 1.2e-11 44.7 0.5 1.5 1 0 0 1 1 1 1 AefR-like transcriptional repressor, C-terminal domain TetR_N PF00440.23 AIM21588.1 - 2.6e-11 43.1 2.7 1.2e-10 41.0 1.9 2.3 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_7 PF02796.15 AIM21588.1 - 0.0036 17.4 0.0 0.021 14.9 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_Tnp_1_2 PF13022.6 AIM21588.1 - 0.0066 16.6 0.0 0.01 16.0 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix of insertion element transposase HTH_29 PF13551.6 AIM21588.1 - 0.013 15.5 1.1 0.71 9.9 0.1 2.7 2 0 0 2 2 2 0 Winged helix-turn helix TetR_C_11 PF16859.5 AIM21588.1 - 0.033 14.5 1.7 0.033 14.5 1.7 2.4 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain HTH_17 PF12728.7 AIM21588.1 - 0.12 12.6 0.4 0.61 10.3 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_28 PF13518.6 AIM21588.1 - 0.14 12.3 2.1 9.2 6.5 0.1 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain PEPCK_ATP PF01293.20 AIM21589.1 - 1.8e-209 696.2 0.0 2.1e-209 696.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 AIM21589.1 - 0.0013 18.9 0.7 0.43 10.7 0.1 2.9 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 AIM21589.1 - 0.17 12.2 0.0 0.4 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain 2HCT PF03390.15 AIM21590.1 - 2.8e-144 480.8 48.1 3.2e-144 480.6 48.1 1.0 1 0 0 1 1 1 1 2-hydroxycarboxylate transporter family Peptidase_M10_C PF08548.11 AIM21591.1 - 1.4e-81 273.1 12.7 1.4e-81 273.1 12.7 2.5 3 1 0 3 3 3 1 Peptidase M10 serralysin C terminal HemolysinCabind PF00353.19 AIM21591.1 - 5.2e-20 71.1 23.7 4.3e-11 42.6 6.7 4.5 4 1 1 5 5 5 2 RTX calcium-binding nonapeptide repeat (4 copies) Peptidase_M10 PF00413.24 AIM21591.1 - 8.4e-10 38.7 0.9 2.8e-09 37.0 0.9 1.9 1 1 0 1 1 1 1 Matrixin Reprolysin_5 PF13688.6 AIM21591.1 - 2e-08 34.6 2.3 3.7e-08 33.8 2.3 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 AIM21591.1 - 1.5e-06 28.1 1.8 2.7e-06 27.2 1.8 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 AIM21591.1 - 1.4e-05 25.6 0.3 3.9e-05 24.2 0.3 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 AIM21591.1 - 0.0028 17.6 1.5 0.0054 16.6 1.1 1.6 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 AIM21591.1 - 0.016 14.9 1.4 0.1 12.2 1.4 2.0 1 1 0 1 1 1 0 Astacin (Peptidase family M12A) Peptidase_M43 PF05572.13 AIM21591.1 - 0.019 14.9 0.3 0.036 14.0 0.3 1.4 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A DUF4953 PF16313.5 AIM21591.1 - 0.034 13.3 0.1 0.055 12.7 0.1 1.3 1 0 0 1 1 1 0 Met-zincin DUF2767 PF10965.8 AIM21592.1 - 0.0037 17.2 0.1 0.0051 16.8 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2767) ASCH PF04266.14 AIM21594.1 - 3.4e-21 75.8 0.0 4e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 ASCH domain Peptidase_C39_2 PF13529.6 AIM21595.1 - 0.00032 21.3 0.0 0.0004 21.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase_C39 like family Peptidase_C70 PF12385.8 AIM21595.1 - 0.00072 19.6 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 Papain-like cysteine protease AvrRpt2 Peptidase_C39 PF03412.15 AIM21595.1 - 0.13 12.0 0.0 1.6 8.6 0.0 2.1 2 0 0 2 2 2 0 Peptidase C39 family DUF1480 PF07351.13 AIM21596.1 - 1e-41 141.0 0.2 1.2e-41 140.9 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1480) SCPU PF05229.15 AIM21597.1 - 1.2e-38 132.7 24.4 1.2e-24 87.2 10.2 2.0 2 0 0 2 2 2 2 Spore Coat Protein U domain Usher PF00577.20 AIM21598.1 - 2e-35 122.7 13.7 4.7e-35 121.5 13.5 1.5 1 1 0 1 1 1 1 Outer membrane usher protein PapC_C PF13953.6 AIM21598.1 - 3.1e-09 36.5 1.8 4.7e-09 35.9 0.3 2.1 2 0 0 2 2 2 1 PapC C-terminal domain PapD_N PF00345.20 AIM21599.1 - 1.4e-17 63.7 0.0 2.9e-17 62.7 0.0 1.4 2 0 0 2 2 2 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain SCPU PF05229.15 AIM21600.1 - 1.5e-27 96.7 4.9 1.8e-27 96.4 4.9 1.0 1 0 0 1 1 1 1 Spore Coat Protein U domain SCPU PF05229.15 AIM21601.1 - 8.4e-31 107.2 17.5 1e-30 107.0 17.5 1.1 1 0 0 1 1 1 1 Spore Coat Protein U domain SCPU PF05229.15 AIM21602.1 - 1.5e-33 116.1 12.5 1.8e-33 115.9 12.5 1.1 1 0 0 1 1 1 1 Spore Coat Protein U domain Methyltr_RsmB-F PF01189.17 AIM21603.1 - 8.9e-50 169.1 0.0 1.4e-49 168.4 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 AIM21603.1 - 1.9e-27 95.6 0.0 3.8e-27 94.6 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF Methyltranf_PUA PF13636.6 AIM21603.1 - 9.8e-12 44.7 0.4 2.3e-11 43.5 0.0 1.9 2 0 0 2 2 2 1 RNA-binding PUA-like domain of methyltransferase RsmF Methyltransf_31 PF13847.6 AIM21603.1 - 0.00023 21.0 0.0 0.00037 20.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 AIM21603.1 - 0.0034 17.2 0.0 0.015 15.0 0.0 1.9 2 1 1 3 3 3 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 AIM21603.1 - 0.015 15.4 0.0 0.026 14.6 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 AIM21603.1 - 0.042 14.6 0.0 0.14 12.9 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain MlaD PF02470.20 AIM21604.1 - 5.8e-69 228.4 13.6 8.4e-17 61.2 0.1 7.3 7 0 0 7 7 7 7 MlaD protein MreC PF04085.14 AIM21604.1 - 1.2 9.1 9.1 32 4.4 0.6 4.9 5 2 0 5 5 5 0 rod shape-determining protein MreC PqiA PF04403.13 AIM21605.1 - 5.9e-87 289.3 32.8 4.6e-47 159.7 16.0 2.0 2 0 0 2 2 2 2 Paraquat-inducible protein A zf-LITAF-like PF10601.9 AIM21605.1 - 0.14 12.4 6.6 0.53 10.6 0.0 3.4 2 1 1 3 3 3 0 LITAF-like zinc ribbon domain Tmemb_55A PF09788.9 AIM21605.1 - 0.25 10.4 5.6 4.9 6.2 0.3 3.0 2 1 1 3 3 3 0 Transmembrane protein 55A DZR PF12773.7 AIM21605.1 - 0.42 10.7 4.4 13 5.9 0.0 2.4 2 0 0 2 2 2 0 Double zinc ribbon zf-HIT PF04438.16 AIM21605.1 - 4.6 7.2 11.0 4.6 7.2 5.1 2.3 2 0 0 2 2 2 0 HIT zinc finger GAF_2 PF13185.6 AIM21606.1 - 1.4e-09 38.3 0.1 1.8e-09 38.0 0.1 1.1 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 AIM21606.1 - 3e-05 24.6 0.1 3.5e-05 24.4 0.1 1.1 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 AIM21606.1 - 0.0034 17.7 0.0 0.0041 17.5 0.0 1.3 1 1 0 1 1 1 1 GAF domain ProQ PF04352.13 AIM21607.1 - 3.2e-43 146.1 0.1 6.3e-43 145.1 0.1 1.5 1 0 0 1 1 1 1 ProQ/FINO family ProQ_C PF17516.2 AIM21607.1 - 5.4e-25 86.6 0.4 9.9e-25 85.7 0.4 1.5 1 0 0 1 1 1 1 ProQ C-terminal domain DUF4407 PF14362.6 AIM21607.1 - 0.084 12.2 2.7 0.1 12.0 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PARP_reg PF02877.14 AIM21607.1 - 0.1 12.7 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase, regulatory domain CRF PF00473.17 AIM21607.1 - 0.32 11.1 6.9 1.4 9.1 7.2 1.9 2 0 0 2 2 2 0 Corticotropin-releasing factor family TSP_NTD PF17804.1 AIM21608.1 - 3.8e-58 197.0 3.2 3.8e-58 197.0 3.2 1.8 2 0 0 2 2 2 1 Tail specific protease N-terminal domain Peptidase_S41 PF03572.18 AIM21608.1 - 2.9e-51 173.3 0.1 5.8e-51 172.3 0.1 1.5 1 0 0 1 1 1 1 Peptidase family S41 DUF3340 PF11818.8 AIM21608.1 - 1.4e-41 142.3 2.8 2.6e-41 141.4 2.8 1.5 1 0 0 1 1 1 1 C-terminal domain of tail specific protease (DUF3340) PDZ PF00595.24 AIM21608.1 - 8.5e-15 54.9 0.2 1.9e-14 53.7 0.2 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 AIM21608.1 - 2.1e-07 30.7 0.8 9.1e-07 28.6 0.8 2.1 1 1 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 AIM21608.1 - 0.00072 19.8 0.7 0.0024 18.1 0.7 1.9 1 1 0 1 1 1 1 PDZ domain EamA PF00892.20 AIM21609.1 - 5.3e-24 84.9 41.4 4.7e-15 56.0 13.6 2.0 2 0 0 2 2 2 2 EamA-like transporter family EVC2_like PF12297.8 AIM21609.1 - 0.76 8.4 1.6 1.2 7.7 1.6 1.3 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein SLATT_1 PF18181.1 AIM21609.1 - 6.9 6.6 7.6 0.41 10.6 1.6 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 Staph_opine_DH PF10100.9 AIM21610.1 - 4e-167 556.2 0.0 4.5e-167 556.0 0.0 1.0 1 0 0 1 1 1 1 Staphylopine dehydrogenase Octopine_DH PF02317.17 AIM21610.1 - 0.003 17.6 0.0 0.008 16.3 0.0 1.7 1 1 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain DUF4518 PF15008.6 AIM21610.1 - 0.022 13.9 0.0 0.034 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) Shikimate_DH PF01488.20 AIM21610.1 - 0.048 13.7 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAS PF03059.16 AIM21611.1 - 1.9e-08 34.0 0.0 2.7e-08 33.5 0.0 1.2 1 1 0 1 1 1 1 Nicotianamine synthase protein Toprim_2 PF13155.6 AIM21611.1 - 0.00073 19.9 0.0 0.0019 18.6 0.0 1.7 1 0 0 1 1 1 1 Toprim-like AlaDh_PNT_C PF01262.21 AIM21611.1 - 0.038 13.3 0.0 0.056 12.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain CorA PF01544.18 AIM21611.1 - 0.17 11.2 2.7 0.23 10.7 2.7 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein ACP_syn_III_C PF08541.10 AIM21611.1 - 0.17 12.1 0.1 1.3 9.2 0.0 2.3 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ParE_toxin PF05016.15 AIM21611.1 - 0.47 11.1 2.7 4 8.1 0.0 2.7 2 1 1 3 3 3 0 ParE toxin of type II toxin-antitoxin system, parDE ABC_tran PF00005.27 AIM21612.1 - 1.6e-14 54.6 0.0 2.2e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AIM21612.1 - 0.0012 18.3 0.0 0.0015 18.0 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AIM21612.1 - 0.0073 16.2 0.0 0.0085 15.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system FecCD PF01032.18 AIM21613.1 - 8.6e-86 287.8 44.7 1e-85 287.5 44.7 1.0 1 0 0 1 1 1 1 FecCD transport family ABC-3 PF00950.17 AIM21613.1 - 0.024 14.1 30.8 0.013 15.0 27.2 2.0 1 1 1 2 2 2 0 ABC 3 transport family Peripla_BP_2 PF01497.18 AIM21614.1 - 1.2e-25 90.5 0.0 1.4e-25 90.3 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein Peptidase_M48 PF01435.18 AIM21615.1 - 1.1e-39 136.3 0.1 1.9e-39 135.5 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 AIM21615.1 - 8e-05 22.0 0.0 0.00015 21.1 0.0 1.5 1 0 0 1 1 1 1 BlaR1 peptidase M56 Peptidase_M1 PF01433.20 AIM21615.1 - 0.0044 16.6 0.0 0.0071 15.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Myc_target_1 PF15179.6 AIM21615.1 - 0.0099 15.8 0.3 0.026 14.4 0.1 1.8 2 0 0 2 2 2 1 Myc target protein 1 SprT-like PF10263.9 AIM21615.1 - 0.019 14.8 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 SprT-like family MFS_1 PF07690.16 AIM21617.1 - 1e-48 166.1 39.4 1e-48 166.1 39.4 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 AIM21617.1 - 0.00044 19.7 12.6 0.00044 19.7 12.6 2.3 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 AIM21617.1 - 0.067 12.0 15.7 0.069 12.0 5.5 2.3 2 0 0 2 2 2 0 MFS_1 like family OATP PF03137.20 AIM21617.1 - 0.47 8.7 6.3 4.5 5.4 2.0 2.5 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family IclR PF01614.18 AIM21618.1 - 4.2e-44 149.5 1.3 8.1e-43 145.3 0.1 2.3 3 0 0 3 3 2 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 AIM21618.1 - 1.3e-14 53.7 0.2 6.4e-14 51.5 0.0 2.2 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_24 PF13412.6 AIM21618.1 - 4.6e-05 22.9 0.0 0.00014 21.4 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 AIM21618.1 - 0.00014 21.6 0.0 0.00091 19.0 0.0 2.2 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family TrmB PF01978.19 AIM21618.1 - 0.00017 21.4 0.2 0.002 17.9 0.0 2.4 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB PadR PF03551.14 AIM21618.1 - 0.00041 20.3 0.3 0.04 13.9 0.1 2.5 2 0 0 2 2 2 1 Transcriptional regulator PadR-like family HTH_11 PF08279.12 AIM21618.1 - 0.0017 18.2 0.0 0.004 17.1 0.0 1.6 1 0 0 1 1 1 1 HTH domain MarR_2 PF12802.7 AIM21618.1 - 0.0029 17.5 0.0 0.0089 15.9 0.0 1.8 1 0 0 1 1 1 1 MarR family MarR PF01047.22 AIM21618.1 - 0.008 16.1 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.20 AIM21618.1 - 0.0083 16.5 0.0 0.027 14.8 0.0 1.9 1 0 0 1 1 1 1 Transcriptional regulator Fe_dep_repress PF01325.19 AIM21618.1 - 0.011 15.9 0.1 0.041 14.1 0.0 2.0 2 0 0 2 2 1 0 Iron dependent repressor, N-terminal DNA binding domain FUR PF01475.19 AIM21618.1 - 0.011 15.8 0.0 0.021 15.0 0.0 1.5 1 0 0 1 1 1 0 Ferric uptake regulator family HTH_45 PF14947.6 AIM21618.1 - 0.014 15.3 0.3 0.03 14.3 0.1 1.6 2 0 0 2 2 2 0 Winged helix-turn-helix Mga PF05043.13 AIM21618.1 - 0.03 14.9 0.0 0.066 13.8 0.0 1.5 1 0 0 1 1 1 0 Mga helix-turn-helix domain HTH_6 PF01418.17 AIM21618.1 - 0.038 14.0 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family HTH_27 PF13463.6 AIM21618.1 - 0.049 14.1 0.0 0.19 12.2 0.0 2.0 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_34 PF13601.6 AIM21618.1 - 0.073 13.3 0.1 0.2 11.9 0.1 1.7 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_Crp_2 PF13545.6 AIM21618.1 - 0.093 12.7 0.1 0.31 11.1 0.1 1.9 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_20 PF12840.7 AIM21618.1 - 0.096 12.8 0.3 0.53 10.4 0.0 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain FeoC PF09012.10 AIM21618.1 - 0.19 11.8 0.1 0.5 10.5 0.0 1.7 2 0 0 2 2 1 0 FeoC like transcriptional regulator BPD_transp_1 PF00528.22 AIM21619.1 - 2.2e-15 56.9 15.3 2.2e-15 56.9 15.3 2.1 1 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 AIM21620.1 - 3.6e-16 59.4 22.2 3.6e-16 59.4 22.2 2.2 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 AIM21621.1 - 6.4e-34 117.4 0.0 9.5e-34 116.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter TOBE_2 PF08402.10 AIM21621.1 - 6.1e-11 42.3 0.0 2.4e-10 40.4 0.0 2.1 1 0 0 1 1 1 1 TOBE domain AAA_21 PF13304.6 AIM21621.1 - 3.9e-10 40.0 1.1 0.00054 19.9 0.1 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIM21621.1 - 6.8e-05 22.4 0.0 0.37 10.2 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AIM21621.1 - 0.0004 20.1 0.0 0.00085 19.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AIM21621.1 - 0.00041 20.8 0.3 0.0013 19.2 0.3 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AIM21621.1 - 0.00093 19.5 0.1 0.0033 17.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 AIM21621.1 - 0.0017 18.8 0.0 0.0091 16.4 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 AIM21621.1 - 0.0036 17.1 0.4 0.0083 15.9 0.1 1.7 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 AIM21621.1 - 0.015 15.2 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 AIM21621.1 - 0.019 15.5 0.1 0.03 14.8 0.1 1.2 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 AIM21621.1 - 0.024 13.5 0.0 1.5 7.5 0.0 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_15 PF13175.6 AIM21621.1 - 0.03 14.0 0.0 0.055 13.2 0.0 1.4 2 0 0 2 2 1 0 AAA ATPase domain T2SSE PF00437.20 AIM21621.1 - 0.033 13.2 0.0 0.052 12.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.6 AIM21621.1 - 0.035 14.4 0.2 0.097 13.0 0.2 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AIM21621.1 - 0.036 14.2 0.1 0.11 12.7 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AIM21621.1 - 0.053 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain RecA PF00154.21 AIM21621.1 - 0.054 13.0 0.0 0.086 12.3 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein Mg_chelatase PF01078.21 AIM21621.1 - 0.065 12.6 0.0 0.19 11.1 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 AIM21621.1 - 0.082 12.8 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain CbiA PF01656.23 AIM21621.1 - 0.084 12.9 0.0 0.16 12.1 0.0 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.12 AIM21621.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 AIM21621.1 - 0.13 12.8 0.0 0.31 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 AIM21621.1 - 0.13 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 AIM21621.1 - 0.14 12.1 0.1 0.31 11.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 AIM21621.1 - 0.15 11.7 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 AIM21621.1 - 0.17 11.5 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 AIM21621.1 - 0.19 12.0 0.3 0.43 10.8 0.1 1.7 2 0 0 2 2 1 0 AAA domain SBP_bac_1 PF01547.25 AIM21622.1 - 2.2e-24 87.0 3.6 3.3e-24 86.4 3.6 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AIM21622.1 - 1.3e-22 80.4 1.0 1.7e-22 80.0 1.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 AIM21622.1 - 1.4e-21 77.6 1.0 2e-21 77.0 1.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 AIM21622.1 - 4.6e-17 62.5 2.6 6.5e-17 62.0 2.6 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein PolyG_pol PF01518.16 AIM21622.1 - 0.11 11.2 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Sigma NS protein UTRA PF07702.13 AIM21623.1 - 6.1e-32 110.4 0.4 1.7e-31 109.0 0.1 1.7 2 0 0 2 2 2 1 UTRA domain GntR PF00392.21 AIM21623.1 - 8.5e-20 70.2 0.0 1.3e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_41 PF14502.6 AIM21623.1 - 0.016 14.9 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_DeoR PF08220.12 AIM21623.1 - 0.09 12.5 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Aminotran_5 PF00266.19 AIM21624.1 - 4.1e-26 91.8 0.0 5.3e-26 91.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 AIM21624.1 - 0.0019 17.4 0.0 0.0072 15.5 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Hydrolase PF00702.26 AIM21625.1 - 1.1e-06 29.1 0.0 1.8e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 AIM21625.1 - 0.034 14.2 0.0 0.049 13.7 0.0 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase TarH PF02203.15 AIM21625.1 - 0.14 12.1 0.1 0.27 11.2 0.1 1.4 1 0 0 1 1 1 0 Tar ligand binding domain homologue SDF PF00375.18 AIM21626.1 - 1.3e-104 350.3 37.9 1.6e-104 350.0 37.9 1.1 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family YdjM PF04307.14 AIM21627.1 - 1.3e-34 119.0 5.9 1.6e-34 118.7 5.9 1.0 1 0 0 1 1 1 1 LexA-binding, inner membrane-associated putative hydrolase DUF2227 PF09988.9 AIM21627.1 - 0.032 14.1 2.8 0.13 12.1 0.6 2.2 1 1 1 2 2 2 0 Uncharacterized metal-binding protein (DUF2227) HAD_2 PF13419.6 AIM21628.1 - 2.2e-26 93.0 0.0 2.7e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AIM21628.1 - 4.5e-15 56.5 0.0 9.8e-14 52.1 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AIM21628.1 - 0.0001 22.3 0.0 0.00016 21.6 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 AIM21628.1 - 0.00018 22.0 0.1 0.00044 20.7 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AIM21628.1 - 0.14 12.3 0.1 1.3 9.1 0.1 2.4 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase YniB PF14002.6 AIM21629.1 - 5.6e-81 270.2 4.2 6.4e-81 270.0 4.2 1.0 1 0 0 1 1 1 1 YniB-like protein DUF2721 PF11026.8 AIM21629.1 - 0.0012 18.8 0.5 0.082 12.8 0.0 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF2721) DUF2973 PF11189.8 AIM21629.1 - 0.17 12.0 1.2 0.45 10.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2973) DUF2839 PF10999.8 AIM21629.1 - 2.1 8.8 4.0 2 8.9 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) DUF2207 PF09972.9 AIM21629.1 - 4.5 5.9 7.7 16 4.1 7.7 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) TM_helix PF05552.12 AIM21629.1 - 6.7 6.8 10.9 0.27 11.2 3.8 2.4 2 1 1 3 3 3 0 Conserved TM helix RseC_MucC PF04246.12 AIM21629.1 - 9.1 6.2 5.8 3.1 7.8 0.3 2.5 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Fructosamin_kin PF03881.14 AIM21630.1 - 7.3e-113 376.5 0.0 8.3e-113 376.4 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 AIM21630.1 - 1.2e-17 64.6 1.8 1.7e-17 64.2 1.8 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family ABC-3 PF00950.17 AIM21631.1 - 3.1e-96 321.8 29.5 3.5e-96 321.7 29.5 1.0 1 0 0 1 1 1 1 ABC 3 transport family FecCD PF01032.18 AIM21631.1 - 6.8e-08 31.9 22.9 6.8e-08 31.9 22.9 1.6 1 1 1 2 2 2 1 FecCD transport family MotA_ExbB PF01618.16 AIM21631.1 - 0.11 12.3 1.4 0.36 10.6 1.4 1.9 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family Phage_holin_2_3 PF16080.5 AIM21631.1 - 6.2 6.7 12.7 3.8 7.3 0.6 3.7 4 0 0 4 4 4 0 Bacteriophage holin family HP1 ABC-3 PF00950.17 AIM21632.1 - 9.6e-89 297.3 33.1 1.1e-88 297.1 33.1 1.0 1 0 0 1 1 1 1 ABC 3 transport family FecCD PF01032.18 AIM21632.1 - 2.4e-08 33.4 33.4 5.9e-08 32.1 33.4 1.7 1 1 0 1 1 1 1 FecCD transport family ABC_tran PF00005.27 AIM21633.1 - 2.9e-30 105.6 0.0 4.1e-30 105.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIM21633.1 - 2.6e-10 40.6 2.7 9e-06 25.7 0.1 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIM21633.1 - 8e-06 25.4 0.5 0.00011 21.7 0.5 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AIM21633.1 - 3.9e-05 23.3 0.3 8.1e-05 22.3 0.3 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AIM21633.1 - 0.0013 19.1 0.1 0.0028 18.0 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain SbcCD_C PF13558.6 AIM21633.1 - 0.0019 18.4 0.1 0.021 15.1 0.1 2.4 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 AIM21633.1 - 0.03 14.2 0.1 0.055 13.4 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 AIM21633.1 - 0.053 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase NACHT PF05729.12 AIM21633.1 - 0.055 13.4 0.3 0.12 12.2 0.1 1.6 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.6 AIM21633.1 - 0.058 13.9 0.6 0.1 13.1 0.6 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AIM21633.1 - 0.059 13.1 0.1 0.18 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 AIM21633.1 - 0.066 13.4 0.1 0.28 11.3 0.0 2.1 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 AIM21633.1 - 0.087 12.5 0.0 0.55 9.9 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.22 AIM21633.1 - 0.16 11.1 0.6 0.4 9.8 0.4 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA_22 PF13401.6 AIM21633.1 - 0.25 11.6 1.4 1 9.6 0.3 2.1 2 0 0 2 2 2 0 AAA domain ZnuA PF01297.17 AIM21634.1 - 6.7e-80 268.2 0.0 7.5e-80 268.0 0.0 1.0 1 0 0 1 1 1 1 Zinc-uptake complex component A periplasmic GhoS PF11080.8 AIM21635.1 - 6.8e-31 106.1 0.0 7.6e-31 106.0 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease GhoS N_Asn_amidohyd PF14736.6 AIM21635.1 - 0.07 12.3 0.1 0.082 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein N-terminal asparagine amidohydrolase SLT PF01464.20 AIM21636.1 - 7.3e-28 96.6 0.3 1.2e-27 95.9 0.3 1.3 1 0 0 1 1 1 1 Transglycosylase SLT domain SLT_2 PF13406.6 AIM21636.1 - 0.0041 16.4 0.0 0.0062 15.8 0.0 1.2 1 0 0 1 1 1 1 Transglycosylase SLT domain Phage_lysozyme2 PF18013.1 AIM21636.1 - 0.024 14.6 0.0 0.033 14.2 0.0 1.3 1 0 0 1 1 1 0 Phage tail lysozyme Gluconate_2-dh3 PF13618.6 AIM21637.1 - 4e-40 137.2 0.0 5.5e-40 136.7 0.0 1.2 1 0 0 1 1 1 1 Gluconate 2-dehydrogenase subunit 3 UCR_Fe-S_N PF10399.9 AIM21637.1 - 0.096 12.0 0.5 0.28 10.6 0.5 1.8 1 1 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal GMC_oxred_C PF05199.13 AIM21638.1 - 6.6e-22 78.6 0.0 1.5e-21 77.4 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 AIM21638.1 - 4.7e-09 36.1 0.0 8.5e-08 31.9 0.0 2.4 2 1 0 2 2 2 1 GMC oxidoreductase FAD_binding_3 PF01494.19 AIM21638.1 - 0.029 13.6 0.1 0.079 12.2 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 AIM21638.1 - 0.055 14.0 1.3 1.4 9.5 0.6 2.7 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 AIM21638.1 - 0.07 12.8 0.1 0.55 9.9 0.1 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 AIM21638.1 - 0.096 11.9 0.1 1.7 7.8 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 AIM21638.1 - 0.19 11.1 0.0 0.63 9.4 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Cytochrom_C PF00034.21 AIM21639.1 - 1.6e-24 86.8 0.0 1.4e-09 38.9 0.0 3.5 3 1 0 3 3 3 3 Cytochrome c Cytochrome_CBB3 PF13442.6 AIM21639.1 - 2.8e-22 78.8 0.1 6.8e-11 42.3 0.0 4.0 3 1 0 3 3 3 3 Cytochrome C oxidase, cbb3-type, subunit III Paired_CXXCH_1 PF09699.10 AIM21639.1 - 0.0004 20.1 2.6 7 6.5 0.1 3.3 3 0 0 3 3 3 3 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrom_C550 PF14495.6 AIM21639.1 - 0.0015 18.3 1.6 6.6 6.5 0.0 4.2 3 2 1 4 4 4 2 Cytochrome c-550 domain DHOR PF06537.11 AIM21639.1 - 0.0043 15.8 0.0 0.59 8.7 0.0 2.8 3 0 0 3 3 3 1 Di-haem oxidoreductase, putative peroxidase PSCyt1 PF07635.11 AIM21639.1 - 0.71 10.5 5.7 17 6.1 0.0 5.0 6 0 0 6 6 6 0 Planctomycete cytochrome C GSu_C4xC__C2xCH PF09698.10 AIM21639.1 - 6.3 7.7 10.9 16 6.4 0.1 3.9 4 0 0 4 4 4 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) DHC PF09626.10 AIM21639.1 - 8.6 7.3 6.7 65 4.4 0.0 3.7 3 1 1 4 4 4 0 Dihaem cytochrome c DUF3961 PF13106.6 AIM21640.1 - 0.23 11.1 0.1 0.23 11.1 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3961) Peripla_BP_2 PF01497.18 AIM21641.1 - 7.8e-23 81.3 0.0 1e-22 80.9 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein Aromatic_hydrox PF11723.8 AIM21641.1 - 0.023 14.2 0.0 3.7 7.0 0.0 2.1 2 0 0 2 2 2 0 Homotrimeric ring hydroxylase Pou PF00157.17 AIM21641.1 - 0.14 12.2 0.0 1.3 9.1 0.0 2.2 2 0 0 2 2 2 0 Pou domain - N-terminal to homeobox domain MarC PF01914.17 AIM21642.1 - 7.4e-64 214.9 11.0 8.4e-64 214.7 11.0 1.0 1 0 0 1 1 1 1 MarC family integral membrane protein DUF3784 PF12650.7 AIM21642.1 - 0.42 10.8 0.2 0.42 10.8 0.2 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF3784) RseC_MucC PF04246.12 AIM21642.1 - 0.69 9.9 5.2 1.9 8.5 0.1 2.4 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Mntp PF02659.15 AIM21642.1 - 0.75 9.5 14.5 0.49 10.1 2.4 2.6 1 1 1 2 2 2 0 Putative manganese efflux pump Cullin PF00888.22 AIM21644.1 - 0.00091 18.0 3.1 0.0012 17.6 3.1 1.0 1 0 0 1 1 1 1 Cullin family MCU PF04678.13 AIM21644.1 - 0.011 15.8 3.4 0.019 15.0 3.4 1.3 1 0 0 1 1 1 0 Mitochondrial calcium uniporter EMP24_GP25L PF01105.24 AIM21644.1 - 0.011 15.6 0.2 0.011 15.6 0.2 2.0 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF2379 PF09543.10 AIM21644.1 - 0.15 12.2 6.3 0.31 11.2 6.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2379) Nuc_sug_transp PF04142.15 AIM21644.1 - 0.2 10.8 8.0 1.4 8.0 4.3 2.2 2 0 0 2 2 2 0 Nucleotide-sugar transporter DUF3107 PF11305.8 AIM21644.1 - 0.33 11.2 3.0 4.4 7.6 1.9 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3107) CPP1-like PF11833.8 AIM21644.1 - 0.35 10.5 0.0 0.35 10.5 0.0 3.1 2 1 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like KELK PF15796.5 AIM21644.1 - 0.49 10.9 10.4 0.17 12.4 7.6 1.6 2 0 0 2 2 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF16 PF01519.16 AIM21644.1 - 0.63 10.6 10.5 0.081 13.4 4.7 2.0 1 1 1 2 2 2 0 Protein of unknown function DUF16 Tox-REase-7 PF15649.6 AIM21644.1 - 0.68 10.3 4.5 1.3 9.4 4.5 1.4 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 7 DUF3792 PF12670.7 AIM21644.1 - 0.93 9.7 24.5 3.4 7.9 20.6 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3792) DUF4600 PF15372.6 AIM21644.1 - 2.4 8.6 9.8 16 5.9 5.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) AAA_23 PF13476.6 AIM21644.1 - 4.8 7.6 8.7 6.6 7.2 8.7 1.2 1 0 0 1 1 1 0 AAA domain T3SS_needle_E PF08988.10 AIM21644.1 - 5.7 7.2 8.6 48 4.2 0.1 3.1 2 1 1 3 3 3 0 Type III secretion system, cytoplasmic E component of needle tRNA-synt_2b PF00587.25 AIM21646.1 - 1.1e-48 165.6 0.0 5.1e-48 163.4 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 AIM21646.1 - 9.8e-24 83.3 1.4 3.5e-23 81.6 1.4 2.0 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 AIM21646.1 - 2e-14 53.4 0.0 4e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 AIM21646.1 - 1.3e-12 47.6 0.1 6.4e-12 45.4 0.0 2.2 2 0 0 2 2 2 1 TGS domain IF3_C PF00707.22 AIM21647.1 - 1.5e-36 124.2 0.5 2.2e-36 123.7 0.5 1.2 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.16 AIM21647.1 - 0.021 15.1 0.8 0.066 13.5 0.8 1.9 1 0 0 1 1 1 0 Translation initiation factor IF-3, N-terminal domain DUF2303 PF10065.9 AIM21647.1 - 0.029 13.5 0.1 0.034 13.3 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2303) Ribosomal_L35p PF01632.19 AIM21648.1 - 4.3e-23 81.6 8.7 4.6e-23 81.5 8.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L35 Ribosomal_L20 PF00453.18 AIM21649.1 - 7.9e-49 164.2 9.0 9e-49 164.0 9.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L20 SMC_ScpA PF02616.14 AIM21649.1 - 0.0091 15.9 0.2 0.014 15.4 0.2 1.2 1 0 0 1 1 1 1 Segregation and condensation protein ScpA tRNA-synt_2d PF01409.20 AIM21650.1 - 3.4e-107 357.5 0.1 4.2e-107 357.2 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) Phe_tRNA-synt_N PF02912.18 AIM21650.1 - 1.1e-25 89.3 0.3 2.5e-25 88.2 0.2 1.7 2 0 0 2 2 2 1 Aminoacyl tRNA synthetase class II, N-terminal domain tRNA_synthFbeta PF17759.1 AIM21650.1 - 0.00014 21.4 0.0 0.00062 19.3 0.0 2.0 2 1 1 3 3 3 1 Phenylalanyl tRNA synthetase beta chain CLM domain B3_4 PF03483.17 AIM21651.1 - 1.5e-70 236.4 0.0 2.3e-70 235.8 0.0 1.3 1 0 0 1 1 1 1 B3/4 domain tRNA_synthFbeta PF17759.1 AIM21651.1 - 8.9e-56 188.7 0.0 1.6e-55 187.9 0.0 1.4 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain FDX-ACB PF03147.14 AIM21651.1 - 6.3e-29 100.3 0.1 1.2e-28 99.4 0.1 1.5 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain tRNA_bind PF01588.20 AIM21651.1 - 2.9e-27 94.6 0.1 6.6e-27 93.5 0.1 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain B5 PF03484.15 AIM21651.1 - 1.1e-21 76.9 0.1 4e-21 75.1 0.1 2.1 1 0 0 1 1 1 1 tRNA synthetase B5 domain PhetRS_B1 PF18262.1 AIM21651.1 - 0.026 14.7 0.0 8 6.8 0.0 3.6 4 0 0 4 4 4 0 Phe-tRNA synthetase beta subunit B1 domain Bac_DNA_binding PF00216.21 AIM21652.1 - 9.5e-31 105.9 0.1 1.1e-30 105.7 0.1 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 AIM21652.1 - 6.1e-08 32.8 0.0 7.5e-08 32.5 0.0 1.0 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_bac_2 PF18175.1 AIM21652.1 - 3.7e-06 26.7 0.0 5.7e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 CCDC81-like prokaryotic HU domain 2 HU-CCDC81_euk_2 PF18289.1 AIM21652.1 - 0.014 15.5 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 2 HU-DNA_bdg PF14848.6 AIM21652.1 - 0.062 13.3 0.0 0.72 9.9 0.0 2.0 2 0 0 2 2 2 0 DNA-binding domain DUF2502 PF10697.9 AIM21653.1 - 9.2e-26 90.0 19.2 1.6e-25 89.2 19.2 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2502) FecCD PF01032.18 AIM21654.1 - 2.7e-84 282.9 38.1 3.3e-84 282.5 38.1 1.0 1 0 0 1 1 1 1 FecCD transport family Popeye PF04831.13 AIM21654.1 - 4.2 7.5 5.6 1.6 8.9 1.8 2.3 2 0 0 2 2 2 0 Popeye protein conserved region DUF3087 PF11286.8 AIM21654.1 - 6.1 6.3 8.7 3.3 7.2 0.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3087) GSHPx PF00255.19 AIM21655.1 - 2.1e-38 130.2 0.0 2.6e-38 129.9 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 AIM21655.1 - 0.0015 18.4 0.0 0.0027 17.6 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AIM21655.1 - 0.0039 16.9 0.0 0.072 12.8 0.0 2.0 2 0 0 2 2 2 1 Redoxin ABC_tran PF00005.27 AIM21656.1 - 1e-18 68.2 0.0 1.6e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIM21656.1 - 5.6e-06 26.4 0.1 0.023 14.5 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AIM21656.1 - 0.00077 19.2 0.0 0.0018 18.0 0.0 1.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 AIM21656.1 - 0.00089 18.8 0.0 0.83 9.0 0.1 2.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 AIM21656.1 - 0.0042 17.3 0.0 0.0072 16.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 AIM21656.1 - 0.0059 16.8 0.0 0.01 16.0 0.0 1.4 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Mg_chelatase PF01078.21 AIM21656.1 - 0.0089 15.4 0.2 0.015 14.7 0.2 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 AIM21656.1 - 0.034 14.5 0.9 0.19 12.1 0.9 2.1 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 AIM21656.1 - 0.056 13.4 1.3 0.34 10.8 0.1 2.2 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.6 AIM21656.1 - 0.063 13.8 0.0 0.098 13.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AIM21656.1 - 0.075 13.3 0.3 0.31 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 AIM21656.1 - 0.095 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 AIM21656.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_30 PF13604.6 AIM21656.1 - 0.13 12.0 0.3 0.44 10.2 0.1 2.1 1 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 AIM21656.1 - 0.16 12.0 0.1 0.34 10.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 AIM21656.1 - 0.18 11.7 0.1 0.34 10.8 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase DegT_DnrJ_EryC1 PF01041.17 AIM21657.1 - 8.1e-127 423.4 0.0 9.3e-127 423.3 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 AIM21657.1 - 1.6e-07 30.9 0.0 3.3e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 AIM21657.1 - 2.2e-05 23.2 0.0 3.3e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 AIM21657.1 - 0.00026 20.4 0.2 0.0006 19.2 0.2 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase SepSecS PF05889.13 AIM21657.1 - 0.019 13.7 0.1 0.041 12.6 0.0 1.5 2 0 0 2 2 2 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS OKR_DC_1 PF01276.20 AIM21657.1 - 0.052 12.3 0.0 0.074 11.8 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Glycos_transf_2 PF00535.26 AIM21658.1 - 1e-33 116.5 0.0 1.5e-33 116.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AIM21658.1 - 1.6e-15 57.7 0.3 3.4e-15 56.6 0.3 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 AIM21658.1 - 4.9e-06 26.2 0.0 6.9e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AIM21658.1 - 0.012 16.1 0.0 0.036 14.6 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glyco_hydro_30C PF17189.4 AIM21658.1 - 0.072 13.3 0.1 0.21 11.9 0.1 1.7 2 0 0 2 2 2 0 Glycosyl hydrolase family 30 beta sandwich domain DUF973 PF06157.11 AIM21658.1 - 0.66 9.0 3.9 1 8.4 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF973) Epimerase PF01370.21 AIM21659.1 - 8.1e-43 146.6 0.0 1.4e-42 145.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Formyl_trans_N PF00551.19 AIM21659.1 - 8.9e-26 90.7 0.0 1.4e-25 90.1 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase GDP_Man_Dehyd PF16363.5 AIM21659.1 - 5e-25 88.6 0.0 6.9e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Formyl_trans_C PF02911.18 AIM21659.1 - 6e-18 64.9 0.0 1.6e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain 3Beta_HSD PF01073.19 AIM21659.1 - 0.00012 21.2 0.0 0.00022 20.3 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 AIM21659.1 - 0.00048 20.1 0.0 0.0012 18.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 AIM21659.1 - 0.006 15.8 0.0 0.4 9.8 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein Sacchrp_dh_NADP PF03435.18 AIM21659.1 - 0.02 15.1 0.1 0.051 13.8 0.0 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 AIM21659.1 - 0.088 13.1 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Polysacc_deac_1 PF01522.21 AIM21660.1 - 3.1e-16 59.4 0.0 6.2e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 AIM21660.1 - 0.0036 17.0 0.0 0.011 15.5 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) PMT PF02366.18 AIM21661.1 - 4.4e-35 121.4 16.7 1.1e-34 120.1 16.4 1.8 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_2 PF13231.6 AIM21661.1 - 1.1e-11 45.2 17.0 1.1e-11 45.2 17.0 3.6 3 1 1 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Reticulon PF02453.17 AIM21661.1 - 0.11 12.5 4.5 0.94 9.4 4.3 2.5 2 0 0 2 2 2 0 Reticulon Ceramidase PF05875.12 AIM21661.1 - 0.2 11.0 4.3 0.38 10.1 4.3 1.7 1 1 0 1 1 1 0 Ceramidase EamA PF00892.20 AIM21662.1 - 2.5e-10 40.6 4.6 3.4e-10 40.2 4.6 1.3 1 1 0 1 1 1 1 EamA-like transporter family Multi_Drug_Res PF00893.19 AIM21662.1 - 2.7e-06 27.9 1.3 6e-06 26.8 1.3 1.6 1 1 0 1 1 1 1 Small Multidrug Resistance protein TMEM234 PF10639.9 AIM21662.1 - 4.2e-06 26.8 0.4 5e-06 26.5 0.4 1.2 1 1 0 1 1 1 1 Putative transmembrane family 234 S_4TM PF18159.1 AIM21662.1 - 0.061 12.6 2.5 0.08 12.2 2.5 1.3 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain DUF202 PF02656.15 AIM21662.1 - 0.47 10.9 13.7 0.37 11.3 9.7 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Bax1-I PF01027.20 AIM21662.1 - 3.1 7.6 9.9 0.11 12.3 4.2 1.5 2 0 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 DUF4131 PF13567.6 AIM21662.1 - 9.9 5.8 11.0 2.3 7.8 4.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) EamA PF00892.20 AIM21663.1 - 7.8e-05 22.9 17.0 0.00039 20.6 17.0 1.8 1 1 0 1 1 1 1 EamA-like transporter family Multi_Drug_Res PF00893.19 AIM21663.1 - 0.00036 21.1 4.2 0.00093 19.8 4.1 1.7 1 1 0 1 1 1 1 Small Multidrug Resistance protein NLPC_P60 PF00877.19 AIM21664.1 - 2.6e-29 101.3 0.1 3.2e-29 101.1 0.1 1.1 1 0 0 1 1 1 1 NlpC/P60 family CHAP PF05257.16 AIM21664.1 - 0.0067 17.0 0.0 0.012 16.1 0.0 1.4 1 0 0 1 1 1 1 CHAP domain DUF1175 PF06672.11 AIM21664.1 - 0.038 13.7 0.0 0.19 11.4 0.0 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1175) Peptidase_C92 PF05708.12 AIM21664.1 - 0.14 12.3 0.0 2.5 8.2 0.0 2.2 1 1 1 2 2 2 0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family Lip_prot_lig_C PF10437.9 AIM21665.1 - 5.3e-18 64.8 0.0 1.1e-16 60.5 0.0 2.2 2 0 0 2 2 2 1 Bacterial lipoate protein ligase C-terminus BPL_LplA_LipB PF03099.19 AIM21665.1 - 1e-07 31.9 0.0 1.6e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family EAL PF00563.20 AIM21666.1 - 8.5e-23 81.1 0.0 1.2e-22 80.6 0.0 1.1 1 0 0 1 1 1 1 EAL domain TetR_C_8 PF14278.6 AIM21666.1 - 0.12 12.4 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator C-terminal region UPF0061 PF02696.14 AIM21667.1 - 5e-156 520.1 0.3 6.3e-156 519.8 0.3 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family SurA_N_2 PF13623.6 AIM21667.1 - 0.55 10.1 5.3 0.77 9.6 2.8 2.3 3 0 0 3 3 3 0 SurA N-terminal domain ABC_tran PF00005.27 AIM21668.1 - 3.5e-25 89.1 0.0 5.1e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIM21668.1 - 4.5e-11 43.1 0.2 9.9e-05 22.3 0.0 2.8 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIM21668.1 - 7.5e-09 35.3 0.0 7.1e-08 32.1 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AIM21668.1 - 1.5e-05 25.5 0.2 2.6e-05 24.7 0.2 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 AIM21668.1 - 5.9e-05 23.7 0.0 9.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 AIM21668.1 - 0.00012 22.2 0.0 0.00026 21.2 0.0 1.5 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 AIM21668.1 - 0.00018 21.2 0.0 0.00036 20.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Mg_chelatase PF01078.21 AIM21668.1 - 0.00068 19.1 0.5 0.039 13.3 0.1 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 AIM21668.1 - 0.00079 19.4 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 AIM21668.1 - 0.0079 16.5 0.8 0.037 14.3 0.1 2.2 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 AIM21668.1 - 0.011 15.8 0.0 0.022 14.8 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.6 AIM21668.1 - 0.013 15.8 0.2 0.038 14.2 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_27 PF13514.6 AIM21668.1 - 0.018 14.7 0.0 0.058 13.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 AIM21668.1 - 0.022 14.5 0.1 0.034 13.9 0.1 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 AIM21668.1 - 0.027 14.2 0.0 0.039 13.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AIM21668.1 - 0.045 13.9 0.0 0.14 12.3 0.0 1.9 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 AIM21668.1 - 0.071 13.0 2.6 0.46 10.4 0.1 2.3 1 1 1 2 2 2 0 NACHT domain AAA_25 PF13481.6 AIM21668.1 - 0.075 12.6 0.9 0.85 9.2 0.2 2.4 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 AIM21668.1 - 0.19 12.2 0.0 0.42 11.0 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 AIM21668.1 - 0.22 11.5 0.0 1.4 9.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 AIM21668.1 - 0.25 11.0 0.0 0.43 10.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.8 AIM21668.1 - 0.73 7.3 2.8 0.37 8.2 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) FecCD PF01032.18 AIM21669.1 - 2.4e-95 319.1 35.0 2.8e-95 318.9 35.0 1.0 1 0 0 1 1 1 1 FecCD transport family ABC-3 PF00950.17 AIM21669.1 - 0.015 14.8 17.9 0.0086 15.6 14.7 2.1 1 1 1 2 2 2 0 ABC 3 transport family DUF751 PF05421.11 AIM21669.1 - 0.18 12.6 0.5 0.18 12.6 0.5 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF751) Phage_holin_2_1 PF04971.12 AIM21669.1 - 4.1 7.5 5.2 0.96 9.5 0.6 2.5 2 0 0 2 2 2 0 Bacteriophage P21 holin S Peripla_BP_2 PF01497.18 AIM21670.1 - 3.3e-28 98.9 0.1 4.1e-28 98.5 0.1 1.0 1 0 0 1 1 1 1 Periplasmic binding protein GFRP PF06399.13 AIM21670.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) HemS PF05171.12 AIM21671.1 - 1.5e-85 283.6 2.9 8.6e-43 145.3 0.4 2.2 2 0 0 2 2 2 2 Haemin-degrading HemS.ChuX domain ChuX_HutX PF06228.13 AIM21671.1 - 9e-66 219.7 1.6 2.4e-34 118.0 0.1 2.1 2 0 0 2 2 2 2 Haem utilisation ChuX/HutX TonB_dep_Rec PF00593.24 AIM21672.1 - 1e-47 164.1 22.1 1e-47 164.1 22.1 1.9 1 1 1 2 2 2 2 TonB dependent receptor Plug PF07715.15 AIM21672.1 - 1.2e-23 83.7 1.2 3.5e-23 82.2 1.2 1.8 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 AIM21672.1 - 0.00062 18.9 3.2 0.0014 17.7 0.1 2.2 2 0 0 2 2 2 1 Outer membrane protein beta-barrel family hemP PF10636.9 AIM21673.1 - 9e-17 60.6 0.2 1.1e-16 60.4 0.2 1.1 1 0 0 1 1 1 1 Hemin uptake protein hemP GSHPx PF00255.19 AIM21674.1 - 7e-36 122.1 0.0 8.7e-36 121.8 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase DAHP_synth_1 PF00793.20 AIM21675.1 - 1.7e-103 345.2 0.0 2.1e-103 345.0 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Kinase-PPPase PF03618.14 AIM21676.1 - 1e-73 248.3 0.0 1.2e-73 248.1 0.0 1.0 1 0 0 1 1 1 1 Kinase/pyrophosphorylase Tower PF09121.10 AIM21676.1 - 0.34 11.1 1.9 0.98 9.7 1.6 1.9 2 1 0 2 2 2 0 Tower PPDK_N PF01326.19 AIM21677.1 - 1.1e-118 396.3 0.4 1.6e-118 395.8 0.4 1.2 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers_C PF02896.18 AIM21677.1 - 8.7e-60 202.3 0.0 1.4e-59 201.6 0.0 1.3 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilizers PF00391.23 AIM21677.1 - 2.5e-27 94.4 0.7 7.5e-27 92.9 0.7 1.9 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain HpcH_HpaI PF03328.14 AIM21677.1 - 0.045 12.9 0.2 0.23 10.6 0.0 2.2 2 0 0 2 2 2 0 HpcH/HpaI aldolase/citrate lyase family Polysacc_deac_2 PF04748.13 AIM21677.1 - 0.061 12.5 0.0 0.15 11.2 0.0 1.6 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase AI-2E_transport PF01594.16 AIM21678.1 - 8.7e-50 169.7 39.6 9.9e-50 169.5 39.6 1.0 1 0 0 1 1 1 1 AI-2E family transporter FAD-oxidase_C PF02913.19 AIM21679.1 - 3e-64 217.1 0.0 4.5e-64 216.5 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 AIM21679.1 - 3.9e-37 127.1 0.1 7.8e-37 126.1 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Fer4_8 PF13183.6 AIM21679.1 - 1e-12 48.3 0.4 2.5e-12 47.0 0.4 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain BBE PF08031.12 AIM21679.1 - 0.00025 21.1 0.0 0.00062 19.8 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Fer4_17 PF13534.6 AIM21679.1 - 0.0006 20.3 2.5 0.0067 17.0 2.5 2.4 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_20 PF14691.6 AIM21679.1 - 0.004 16.9 0.1 0.0077 16.0 0.1 1.4 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_18 PF13746.6 AIM21679.1 - 0.032 14.4 0.0 0.067 13.4 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 AIM21679.1 - 0.044 14.4 1.9 0.11 13.1 1.9 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_10 PF13237.6 AIM21679.1 - 0.32 11.1 4.5 1.4 9.1 4.8 1.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain 4HBT PF03061.22 AIM21680.1 - 6.5e-15 55.3 0.4 1e-14 54.7 0.4 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 AIM21680.1 - 0.064 13.4 0.0 0.075 13.2 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4442) Fe-S_biosyn PF01521.20 AIM21682.1 - 1.7e-18 66.9 0.0 1.9e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis UPF0051 PF01458.17 AIM21683.1 - 4.5e-67 225.9 0.1 5.7e-67 225.6 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) ABC_tran PF00005.27 AIM21684.1 - 2.8e-21 76.5 0.0 4e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AIM21684.1 - 2.5e-08 33.6 0.2 0.002 17.6 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AIM21684.1 - 1.1e-05 25.4 0.1 0.05 13.4 0.1 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AIM21684.1 - 0.00024 20.8 0.1 0.0005 19.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AIM21684.1 - 0.001 19.0 0.1 0.0016 18.4 0.1 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_13 PF13166.6 AIM21684.1 - 0.0058 15.3 0.0 0.0081 14.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 AIM21684.1 - 0.0062 16.5 0.1 4.1 7.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 AIM21684.1 - 0.0099 16.4 0.1 0.018 15.5 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AIM21684.1 - 0.012 15.8 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 AIM21684.1 - 0.019 15.2 0.1 0.038 14.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AIM21684.1 - 0.022 15.3 0.0 0.046 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.6 AIM21684.1 - 0.027 14.1 0.1 0.043 13.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 AIM21684.1 - 0.039 13.7 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase AAA_22 PF13401.6 AIM21684.1 - 0.047 14.0 0.2 0.31 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 AIM21684.1 - 0.056 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain UPF0051 PF01458.17 AIM21685.1 - 1.1e-72 244.3 1.7 1.3e-72 244.0 1.7 1.1 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) Aminotran_5 PF00266.19 AIM21686.1 - 2.6e-151 503.8 0.0 2.9e-151 503.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_MocR PF12897.7 AIM21686.1 - 0.0063 15.3 0.0 0.01 14.7 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase SufE PF02657.15 AIM21687.1 - 1.3e-44 151.0 0.0 1.5e-44 150.8 0.0 1.0 1 0 0 1 1 1 1 Fe-S metabolism associated domain Ldt_C PF17969.1 AIM21688.1 - 4.2e-27 94.7 0.1 7.7e-27 93.8 0.1 1.4 1 0 0 1 1 1 1 L,D-transpeptidase C-terminal domain YkuD PF03734.14 AIM21688.1 - 1.2e-18 67.9 0.0 1.9e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain LysM PF01476.20 AIM21688.1 - 0.019 15.0 0.0 0.04 14.0 0.0 1.5 1 0 0 1 1 1 0 LysM domain RelB_leu_zip PF16180.5 AIM21688.1 - 0.084 12.9 1.7 0.14 12.2 0.2 2.2 3 0 0 3 3 3 0 RelB leucine zipper LPP PF04728.13 AIM21689.1 - 2.7e-25 88.5 10.8 3.2e-25 88.2 10.8 1.1 1 0 0 1 1 1 1 Lipoprotein leucine-zipper Alanine_zipper PF11839.8 AIM21689.1 - 0.00022 21.5 9.9 0.00028 21.2 8.3 1.7 1 1 1 2 2 2 1 Alanine-zipper, major outer membrane lipoprotein JIP_LZII PF16471.5 AIM21689.1 - 0.00035 20.7 0.2 0.0034 17.5 0.1 2.0 1 1 1 2 2 2 1 JNK-interacting protein leucine zipper II MctB PF11382.8 AIM21689.1 - 0.00062 19.6 0.9 0.00069 19.4 0.9 1.1 1 0 0 1 1 1 1 Copper transport outer membrane protein, MctB ADIP PF11559.8 AIM21689.1 - 0.0015 18.6 1.6 0.0018 18.4 1.6 1.0 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DivIC PF04977.15 AIM21689.1 - 0.0017 18.1 0.1 0.0021 17.8 0.1 1.3 1 0 0 1 1 1 1 Septum formation initiator TMF_DNA_bd PF12329.8 AIM21689.1 - 0.0022 17.9 0.4 0.0028 17.6 0.4 1.1 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding DUF948 PF06103.11 AIM21689.1 - 0.0025 18.0 0.3 0.0026 18.0 0.3 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) EzrA PF06160.12 AIM21689.1 - 0.0062 14.8 0.9 0.007 14.6 0.9 1.0 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA YscO PF07321.12 AIM21689.1 - 0.009 16.0 2.2 0.01 15.8 2.2 1.0 1 0 0 1 1 1 1 Type III secretion protein YscO NPV_P10 PF05531.12 AIM21689.1 - 0.01 16.3 3.0 0.014 15.8 3.0 1.3 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein TPR_MLP1_2 PF07926.12 AIM21689.1 - 0.011 15.8 2.4 0.013 15.6 2.4 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein EspB_PE PF18625.1 AIM21689.1 - 0.012 16.1 2.5 0.013 15.9 2.5 1.3 1 1 0 1 1 1 0 ESX-1 secreted protein B PE domain DUF1664 PF07889.12 AIM21689.1 - 0.012 15.7 0.2 0.015 15.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.7 AIM21689.1 - 0.018 15.2 1.6 0.02 15.0 1.6 1.1 1 0 0 1 1 1 0 Tropomyosin like DUF16 PF01519.16 AIM21689.1 - 0.019 15.4 0.1 0.024 15.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 ZapB PF06005.12 AIM21689.1 - 0.024 15.1 0.4 0.032 14.7 0.4 1.1 1 0 0 1 1 1 0 Cell division protein ZapB Cluap1 PF10234.9 AIM21689.1 - 0.025 14.0 1.2 0.03 13.7 1.2 1.0 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF3138 PF11336.8 AIM21689.1 - 0.026 13.1 1.2 0.028 13.1 1.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) COG2 PF06148.11 AIM21689.1 - 0.029 14.5 0.2 0.032 14.3 0.2 1.1 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 TolA_bind_tri PF16331.5 AIM21689.1 - 0.031 14.3 0.7 0.044 13.9 0.7 1.3 1 0 0 1 1 1 0 TolA binding protein trimerisation Atg14 PF10186.9 AIM21689.1 - 0.033 13.3 0.4 0.034 13.2 0.4 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 AIM21689.1 - 0.041 12.8 0.6 0.045 12.6 0.6 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein AKNA PF12443.8 AIM21689.1 - 0.054 14.2 0.1 0.063 13.9 0.1 1.2 1 0 0 1 1 1 0 AT-hook-containing transcription factor FlaC_arch PF05377.11 AIM21689.1 - 0.055 13.9 0.2 0.073 13.5 0.2 1.3 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) MbeD_MobD PF04899.12 AIM21689.1 - 0.065 13.4 0.7 0.1 12.7 0.3 1.6 1 1 1 2 2 2 0 MbeD/MobD like SlyX PF04102.12 AIM21689.1 - 0.17 12.6 1.7 0.22 12.2 1.7 1.2 1 0 0 1 1 1 0 SlyX XhlA PF10779.9 AIM21689.1 - 0.83 9.9 6.4 0.25 11.6 1.4 2.2 2 1 1 3 3 2 0 Haemolysin XhlA DUF4407 PF14362.6 AIM21689.1 - 1.7 7.9 8.0 0.27 10.6 3.2 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) PK PF00224.21 AIM21690.1 - 3.6e-152 506.3 9.5 4.7e-152 505.9 9.5 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 AIM21690.1 - 6.2e-28 97.4 1.1 1.8e-27 95.9 1.1 1.9 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 AIM21690.1 - 0.00045 19.4 0.3 0.0012 18.1 0.3 1.7 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 AIM21690.1 - 0.0038 16.3 0.1 0.029 13.4 0.0 2.3 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Cupin_2 PF07883.11 AIM21691.1 - 3.5e-05 23.4 0.0 4.3e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 AIM21691.1 - 0.0024 17.5 0.0 0.0035 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) ASH PF15780.5 AIM21691.1 - 0.058 13.6 0.0 1.4 9.2 0.0 2.1 1 1 1 2 2 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin MatE PF01554.18 AIM21692.1 - 2.9e-74 248.1 33.9 1.8e-38 131.8 5.1 3.2 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 AIM21692.1 - 2.7e-05 24.3 17.0 2.7e-05 24.3 17.0 5.1 2 2 3 5 5 5 2 Polysaccharide biosynthesis C-terminal domain Lum_binding PF00677.17 AIM21693.1 - 2.4e-45 152.4 0.1 3.2e-22 78.3 0.0 2.2 2 0 0 2 2 2 2 Lumazine binding domain Inhibitor_I78 PF11720.8 AIM21694.1 - 3.4e-10 39.8 0.0 4.5e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I78 family LPAM_1 PF08139.12 AIM21694.1 - 0.015 15.7 1.2 0.023 15.2 1.2 1.3 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Neurokinin_B PF03823.14 AIM21694.1 - 1.2 9.2 4.4 3.8 7.6 4.4 2.1 1 1 0 1 1 1 0 Neurokinin B CMAS PF02353.20 AIM21695.1 - 1.5e-101 339.3 0.1 2.1e-101 338.8 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 AIM21695.1 - 2.4e-14 53.8 0.0 5e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AIM21695.1 - 5.8e-13 49.0 0.0 9e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AIM21695.1 - 1.8e-12 47.7 0.0 3.8e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AIM21695.1 - 1e-08 35.1 0.0 1.7e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIM21695.1 - 1.6e-07 32.0 0.0 3.5e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AIM21695.1 - 7e-05 22.4 0.0 0.00013 21.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 AIM21695.1 - 0.00012 21.9 0.0 0.00018 21.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 AIM21695.1 - 0.00026 21.1 0.0 0.00041 20.5 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase ADH_zinc_N PF00107.26 AIM21695.1 - 0.0032 17.4 0.0 0.0059 16.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DOT1 PF08123.13 AIM21695.1 - 0.0067 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_32 PF13679.6 AIM21695.1 - 0.017 15.1 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 AIM21695.1 - 0.022 14.3 0.1 0.04 13.5 0.1 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW TPMT PF05724.11 AIM21695.1 - 0.059 13.0 0.0 1.2 8.7 0.0 2.2 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) RrnaAD PF00398.20 AIM21695.1 - 0.2 10.7 0.0 0.35 9.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MFS_1 PF07690.16 AIM21696.1 - 6.5e-40 137.1 38.1 6.5e-40 137.1 38.1 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AIM21696.1 - 2.2e-08 33.4 3.7 2.2e-08 33.4 3.7 2.4 3 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 AIM21696.1 - 0.75 9.0 29.6 7.2 5.8 29.8 2.2 1 1 1 2 2 2 0 Uncharacterised MFS-type transporter YbfB LysR_substrate PF03466.20 AIM21697.1 - 1.3e-29 103.1 0.7 2.5e-29 102.2 0.7 1.4 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM21697.1 - 1.4e-20 73.0 0.1 2.2e-20 72.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family Peripla_BP_3 PF13377.6 AIM21698.1 - 1.1e-39 136.4 0.0 4.3e-39 134.5 0.0 1.8 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 AIM21698.1 - 2e-34 119.3 0.0 2.4e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_4 PF13407.6 AIM21698.1 - 3.2e-20 72.8 0.0 4.5e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain LacI PF00356.21 AIM21698.1 - 1.7e-19 69.3 0.5 3.2e-19 68.4 0.5 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family HTH_Tnp_ISL3 PF13542.6 AIM21698.1 - 0.0098 15.3 0.3 0.029 13.8 0.3 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_38 PF13936.6 AIM21698.1 - 0.011 15.4 0.2 0.53 10.1 0.1 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_3 PF01381.22 AIM21698.1 - 0.012 15.7 0.0 0.038 14.1 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix PucR PF07905.11 AIM21698.1 - 0.035 14.4 0.0 0.068 13.5 0.0 1.5 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family HTH_24 PF13412.6 AIM21698.1 - 0.036 13.6 0.1 0.67 9.6 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 AIM21698.1 - 0.04 13.7 0.2 0.45 10.4 0.1 2.3 1 1 1 2 2 2 0 Homeodomain-like domain HTH_10 PF04967.12 AIM21698.1 - 0.072 12.9 0.2 0.32 10.8 0.0 2.2 2 0 0 2 2 2 0 HTH DNA binding domain MerR PF00376.23 AIM21698.1 - 0.1 12.4 0.2 0.27 11.0 0.2 1.7 1 0 0 1 1 1 0 MerR family regulatory protein MarR_2 PF12802.7 AIM21698.1 - 0.1 12.5 0.2 10 6.1 0.1 2.6 2 0 0 2 2 2 0 MarR family TetR_N PF00440.23 AIM21698.1 - 0.13 12.0 0.1 0.31 10.9 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family Sod_Fe_C PF02777.18 AIM21699.1 - 2.8e-40 136.6 1.8 9.1e-40 135.0 0.2 2.3 3 0 0 3 3 3 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 AIM21699.1 - 1.3e-34 118.5 2.3 2.4e-34 117.6 2.3 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain NLPC_P60 PF00877.19 AIM21700.1 - 1.5e-32 111.7 0.0 3.7e-32 110.5 0.0 1.7 1 0 0 1 1 1 1 NlpC/P60 family DUF1175 PF06672.11 AIM21700.1 - 0.00035 20.3 0.0 0.2 11.3 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF1175) Peptidase_C92 PF05708.12 AIM21700.1 - 0.0013 18.9 1.5 0.013 15.6 0.0 2.7 2 1 1 3 3 3 1 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family Presenilin PF01080.17 AIM21700.1 - 0.06 12.1 0.3 0.068 11.9 0.3 1.1 1 0 0 1 1 1 0 Presenilin CLN3 PF02487.17 AIM21700.1 - 0.72 8.8 1.8 1.1 8.2 1.8 1.2 1 0 0 1 1 1 0 CLN3 protein Neur_chan_memb PF02932.16 AIM21700.1 - 3 7.8 4.7 3.9 7.5 4.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region GREB1 PF15782.5 AIM21700.1 - 3.1 4.8 7.8 3.8 4.5 7.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Glutaredoxin PF00462.24 AIM21701.1 - 7.2e-19 67.8 0.0 1.2e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin RNase_T PF00929.24 AIM21702.1 - 2.7e-37 128.8 0.0 3.1e-37 128.6 0.0 1.0 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 AIM21702.1 - 5.2e-08 33.0 0.1 2.3e-07 31.0 0.1 1.8 1 1 0 1 1 1 1 3' exoribonuclease, RNase T-like Glyoxalase PF00903.25 AIM21703.1 - 5.5e-26 91.3 0.0 6.4e-26 91.0 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 AIM21703.1 - 5.1e-10 39.6 0.0 3e-09 37.1 0.0 1.8 1 1 1 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 AIM21703.1 - 2.8e-07 31.3 0.0 4.7e-07 30.6 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 AIM21703.1 - 0.0056 16.6 0.0 0.011 15.6 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 AIM21703.1 - 0.035 14.2 0.0 1.3 9.1 0.0 2.1 1 1 0 1 1 1 0 Glyoxalase-like domain CppA_N PF14506.6 AIM21703.1 - 0.066 13.3 0.0 0.096 12.8 0.0 1.3 1 0 0 1 1 1 0 CppA N-terminal Oxidored_FMN PF00724.20 AIM21704.1 - 2e-88 297.0 0.0 2.3e-88 296.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family His_biosynth PF00977.21 AIM21704.1 - 0.0083 15.6 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein DUF934 PF06073.12 AIM21704.1 - 0.094 12.6 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF934) Shikimate_DH PF01488.20 AIM21704.1 - 0.1 12.6 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TetR_C_13 PF16925.5 AIM21705.1 - 1.5e-11 44.3 0.0 2.7e-11 43.4 0.0 1.4 1 1 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 AIM21705.1 - 3.9e-09 36.2 0.1 9.2e-09 35.0 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.6 AIM21705.1 - 0.00077 19.7 4.4 0.00091 19.4 1.2 2.1 1 1 1 2 2 2 1 BetI-type transcriptional repressor, C-terminal TetR_C_24 PF17932.1 AIM21705.1 - 0.04 14.2 0.0 0.082 13.2 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Phage_tail_T PF06223.12 AIM21705.1 - 0.12 12.9 0.0 0.2 12.2 0.0 1.4 1 0 0 1 1 1 0 Minor tail protein T EptA_B_N PF08019.12 AIM21706.1 - 3.3e-49 166.7 9.4 3.3e-49 166.7 9.4 1.6 2 0 0 2 2 2 1 Phosphoethanolamine transferase EptA/EptB Sulfatase PF00884.23 AIM21706.1 - 3.5e-47 161.3 0.6 4.4e-47 161.0 0.6 1.1 1 0 0 1 1 1 1 Sulfatase MAP17 PF15807.5 AIM21706.1 - 0.018 15.3 0.2 0.033 14.4 0.2 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 LRR19-TM PF15176.6 AIM21706.1 - 0.17 11.9 0.4 0.59 10.2 0.4 1.9 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain NAD_binding_10 PF13460.6 AIM21707.1 - 1e-38 133.1 0.4 1.1e-38 132.9 0.4 1.0 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 AIM21707.1 - 3e-10 40.0 0.0 4.7e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 AIM21707.1 - 1e-08 35.0 1.2 1.6e-08 34.4 1.2 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 AIM21707.1 - 5.9e-07 28.8 0.0 7.9e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 AIM21707.1 - 0.00015 21.0 0.1 0.00026 20.2 0.1 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain DapB_N PF01113.20 AIM21707.1 - 0.017 15.3 0.1 0.025 14.7 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus PFK PF00365.20 AIM21707.1 - 0.029 13.7 0.0 0.039 13.3 0.0 1.3 1 1 0 1 1 1 0 Phosphofructokinase NAD_binding_4 PF07993.12 AIM21707.1 - 0.06 12.5 0.0 0.084 12.0 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein Semialdhyde_dh PF01118.24 AIM21707.1 - 0.077 13.4 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.25 AIM21707.1 - 0.1 12.1 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase 3HCDH_N PF02737.18 AIM21707.1 - 0.11 12.3 0.3 0.18 11.7 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YscW PF09619.10 AIM21707.1 - 0.12 12.7 0.0 0.23 11.9 0.0 1.3 1 0 0 1 1 1 0 Type III secretion system lipoprotein chaperone (YscW) LysR_substrate PF03466.20 AIM21708.1 - 6.1e-37 127.0 7.1 1.1e-36 126.2 7.1 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM21708.1 - 5.9e-20 71.0 2.1 5.9e-20 71.0 2.1 1.8 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_24 PF13412.6 AIM21708.1 - 5.8e-05 22.6 0.1 0.0033 16.9 0.0 2.9 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 AIM21708.1 - 0.0011 18.7 0.0 0.0042 16.9 0.0 1.9 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_30 PF13556.6 AIM21708.1 - 0.0015 18.3 0.1 0.0044 16.8 0.1 1.8 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_20 PF12840.7 AIM21708.1 - 0.0043 17.1 0.2 0.024 14.7 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.7 AIM21708.1 - 0.0095 15.8 0.1 0.037 13.9 0.1 2.0 1 0 0 1 1 1 1 MarR family HTH_IclR PF09339.10 AIM21708.1 - 0.11 12.3 2.2 0.25 11.2 0.2 2.8 3 0 0 3 3 3 0 IclR helix-turn-helix domain DUF1289 PF06945.13 AIM21709.1 - 6.3e-19 67.5 5.7 7.8e-19 67.2 5.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1289) Aldo_ket_red PF00248.21 AIM21710.1 - 2.2e-46 158.4 0.0 4e-46 157.6 0.0 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family HemolysinCabind PF00353.19 AIM21711.1 - 1.3e-10 41.0 43.4 5.8e-06 26.2 11.5 6.0 4 2 2 6 6 6 4 RTX calcium-binding nonapeptide repeat (4 copies) Peptidase_S9 PF00326.21 AIM21711.1 - 0.053 13.0 0.4 0.12 11.9 0.4 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 AIM21711.1 - 0.056 12.7 0.1 0.1 11.9 0.1 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AIM21711.1 - 0.077 13.6 2.0 0.13 12.9 0.9 1.9 2 1 0 2 2 2 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 AIM21711.1 - 0.14 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Sod_Cu PF00080.20 AIM21712.1 - 5e-29 101.3 0.3 6.1e-29 101.0 0.3 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) FUSC PF04632.12 AIM21713.1 - 1.7e-177 591.9 26.1 1.9e-177 591.8 26.1 1.0 1 0 0 1 1 1 1 Fusaric acid resistance protein family FUSC_2 PF13515.6 AIM21713.1 - 4.1e-16 59.2 12.1 4.1e-16 59.2 12.1 3.3 2 1 1 3 3 3 1 Fusaric acid resistance protein-like ArAE_1 PF06081.11 AIM21713.1 - 0.0014 18.8 15.4 0.0025 18.0 6.5 3.1 2 1 0 2 2 2 1 Aromatic acid exporter family member 1 ALMT PF11744.8 AIM21713.1 - 0.025 13.4 5.1 0.049 12.5 5.1 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter PHO4 PF01384.20 AIM21713.1 - 2.4 7.1 7.6 6.7 5.6 7.5 2.0 1 1 0 1 1 1 0 Phosphate transporter family HlyD_D23 PF16576.5 AIM21714.1 - 4.9e-15 55.3 0.0 8.6e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 AIM21714.1 - 7.9e-15 54.4 1.0 9.1e-12 44.6 0.0 2.9 3 0 0 3 3 3 2 Biotin-lipoyl like HlyD_3 PF13437.6 AIM21714.1 - 4.2e-13 49.9 0.1 6.2e-09 36.5 0.0 2.5 2 1 0 2 2 2 2 HlyD family secretion protein HlyD PF00529.20 AIM21714.1 - 3.8e-05 23.5 0.0 8.6e-05 22.3 0.0 1.6 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl PF00364.22 AIM21714.1 - 7.7e-05 22.4 0.0 0.57 10.1 0.0 2.5 2 0 0 2 2 2 2 Biotin-requiring enzyme HlyD_2 PF12700.7 AIM21714.1 - 0.0079 15.0 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 HlyD family secretion protein DUF2880 PF11082.8 AIM21714.1 - 0.089 13.1 2.3 0.45 10.9 2.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2880) DUF1656 PF07869.12 AIM21715.1 - 9.9e-14 51.1 4.7 1.3e-13 50.7 4.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1656) MarR PF01047.22 AIM21716.1 - 2.5e-17 62.5 1.0 5.5e-17 61.4 0.2 1.9 2 0 0 2 2 2 1 MarR family MarR_2 PF12802.7 AIM21716.1 - 3e-12 46.2 0.1 6.3e-12 45.2 0.1 1.6 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 AIM21716.1 - 6.6e-12 45.7 0.1 1.1e-11 45.1 0.1 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_Crp_2 PF13545.6 AIM21716.1 - 4.1e-05 23.5 0.3 8.9e-05 22.4 0.3 1.7 1 1 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_24 PF13412.6 AIM21716.1 - 0.0021 17.6 0.1 0.005 16.4 0.1 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 AIM21716.1 - 0.0025 17.6 0.0 0.11 12.3 0.0 2.8 3 0 0 3 3 3 1 Bacterial regulatory protein, arsR family B-block_TFIIIC PF04182.12 AIM21716.1 - 0.0028 17.8 0.0 0.0051 17.0 0.0 1.5 1 1 0 1 1 1 1 B-block binding subunit of TFIIIC RP-C PF03428.13 AIM21716.1 - 0.0068 16.1 0.1 0.019 14.6 0.0 1.8 1 1 1 2 2 2 1 Replication protein C N-terminal domain TrmB PF01978.19 AIM21716.1 - 0.0072 16.2 0.0 0.028 14.3 0.0 1.9 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB GntR PF00392.21 AIM21716.1 - 0.0076 15.9 0.0 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_20 PF12840.7 AIM21716.1 - 0.011 15.8 0.2 0.056 13.5 0.0 2.1 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_IclR PF09339.10 AIM21716.1 - 0.03 14.1 0.0 0.069 13.0 0.0 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain HxlR PF01638.17 AIM21716.1 - 0.031 14.1 0.1 0.062 13.1 0.1 1.6 1 1 0 1 1 1 0 HxlR-like helix-turn-helix HTH_36 PF13730.6 AIM21716.1 - 0.032 14.2 0.0 0.066 13.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain DUF1845 PF08900.11 AIM21716.1 - 0.041 13.6 0.0 0.046 13.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1845) GlnD_UR_UTase PF08335.11 AIM21716.1 - 0.075 13.1 0.2 0.27 11.3 0.1 1.9 1 1 1 2 2 2 0 GlnD PII-uridylyltransferase HTH_1 PF00126.27 AIM21716.1 - 0.095 12.7 0.1 0.59 10.1 0.1 2.2 1 1 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Fe_dep_repress PF01325.19 AIM21716.1 - 0.13 12.5 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Rick_17kDa_Anti PF05433.15 AIM21717.1 - 3.1e-07 30.2 27.5 6.3e-07 29.1 27.5 1.6 1 0 0 1 1 1 1 Glycine zipper 2TM domain Bacteriocin_IIc PF10439.9 AIM21717.1 - 0.0057 16.7 17.1 0.012 15.7 17.1 1.6 1 0 0 1 1 1 1 Bacteriocin class II with double-glycine leader peptide LPAM_1 PF08139.12 AIM21717.1 - 0.009 16.5 2.5 0.022 15.2 2.5 1.7 1 0 0 1 1 1 1 Prokaryotic membrane lipoprotein lipid attachment site Gly-zipper_Omp PF13488.6 AIM21717.1 - 0.047 13.7 26.5 0.051 13.6 25.3 1.7 1 1 0 1 1 1 0 Glycine zipper DUF533 PF04391.12 AIM21717.1 - 0.15 11.6 3.0 0.23 11.0 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Gly-zipper_YMGG PF13441.6 AIM21717.1 - 0.37 10.6 26.9 0.81 9.5 26.9 1.6 1 0 0 1 1 1 0 YMGG-like Gly-zipper AnmK PF03702.14 AIM21718.1 - 1.4e-164 547.5 0.3 1.6e-164 547.3 0.3 1.0 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase MliC PF09864.9 AIM21719.1 - 1.9e-12 46.9 0.1 3e-12 46.3 0.1 1.3 2 0 0 2 2 2 1 Membrane-bound lysozyme-inhibitor of c-type lysozyme LPAM_1 PF08139.12 AIM21719.1 - 0.0089 16.5 2.7 0.0089 16.5 2.7 2.5 2 1 0 2 2 2 1 Prokaryotic membrane lipoprotein lipid attachment site Putative_PNPOx PF01243.20 AIM21720.1 - 5e-23 81.1 0.0 7.4e-23 80.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 AIM21720.1 - 1.5e-19 69.8 1.5 4.1e-19 68.4 1.5 1.8 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region tRNA-synt_1b PF00579.25 AIM21721.1 - 9.1e-89 297.6 0.0 1.1e-88 297.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 AIM21721.1 - 1.2e-06 28.1 0.0 3.3e-06 26.7 0.0 1.8 2 0 0 2 2 2 1 S4 domain S4_2 PF13275.6 AIM21721.1 - 0.0045 16.8 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 S4 domain Orbi_NS3 PF01616.16 AIM21721.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Orbivirus NS3 DUF4214 PF13946.6 AIM21722.1 - 5.9e-14 51.9 2.3 0.0012 18.8 0.0 5.3 3 2 2 5 5 5 4 Domain of unknown function (DUF4214) HRI1 PF16815.5 AIM21722.1 - 0.16 11.6 0.0 0.42 10.3 0.0 1.6 2 0 0 2 2 2 0 Protein HRI1 Phos_pyr_kin PF08543.12 AIM21725.1 - 1.5e-14 54.0 0.0 1.8e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 AIM21725.1 - 5e-09 35.9 0.0 1.5e-08 34.3 0.0 1.7 1 1 0 1 1 1 1 pfkB family carbohydrate kinase GST_C PF00043.25 AIM21726.1 - 1.5e-18 66.8 0.2 2.7e-18 66.0 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 AIM21726.1 - 6.6e-12 45.6 0.0 1.3e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 AIM21726.1 - 1.9e-11 44.0 0.2 3e-11 43.4 0.2 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 AIM21726.1 - 8.3e-11 42.2 0.0 1.5e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AIM21726.1 - 5.8e-10 39.3 0.0 1.3e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 AIM21726.1 - 2e-09 37.3 2.5 2e-09 37.3 2.5 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 AIM21726.1 - 0.00092 19.1 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain GST_C_6 PF17171.4 AIM21726.1 - 0.0027 17.5 0.4 0.005 16.6 0.4 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DHDPS PF00701.22 AIM21727.1 - 4.2e-67 225.9 0.0 4.8e-67 225.7 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family CbiD PF01888.17 AIM21727.1 - 0.0028 17.0 0.1 0.099 11.9 0.1 2.4 1 1 1 2 2 2 1 CbiD DUF3343 PF11823.8 AIM21727.1 - 0.12 11.8 0.0 0.32 10.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) DUF3811 PF11656.8 AIM21728.1 - 2e-35 121.0 4.0 2.2e-35 120.9 4.0 1.0 1 0 0 1 1 1 1 YjbD family (DUF3811) DUF1104 PF06518.11 AIM21728.1 - 0.013 15.9 7.7 0.015 15.6 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) HD PF01966.22 AIM21729.1 - 1.3e-09 38.3 0.9 2.6e-09 37.4 0.9 1.4 1 0 0 1 1 1 1 HD domain SnoaL_2 PF12680.7 AIM21730.1 - 2.7e-13 50.4 0.2 3e-13 50.3 0.2 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 AIM21730.1 - 5.6e-05 22.9 0.0 7.1e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase DUF4440 PF14534.6 AIM21730.1 - 0.032 14.6 0.1 0.041 14.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) AzlD PF05437.12 AIM21731.1 - 0.081 13.1 0.1 0.099 12.8 0.1 1.1 1 0 0 1 1 1 0 Branched-chain amino acid transport protein (AzlD) SKG6 PF08693.10 AIM21731.1 - 0.18 11.2 1.0 2.5 7.6 0.1 2.2 2 0 0 2 2 2 0 Transmembrane alpha-helix domain SnoaL_2 PF12680.7 AIM21732.1 - 1e-15 58.2 0.3 1.2e-15 58.0 0.3 1.0 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 AIM21732.1 - 6.4e-05 23.3 0.1 7.3e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) LEH PF07858.12 AIM21732.1 - 0.0001 22.4 0.1 0.00013 22.1 0.1 1.1 1 0 0 1 1 1 1 Limonene-1,2-epoxide hydrolase catalytic domain SnoaL_3 PF13474.6 AIM21732.1 - 0.00021 21.6 0.1 0.00029 21.1 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 AIM21732.1 - 0.00055 19.7 1.2 0.021 14.6 1.2 2.2 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase Ribonuc_L-PSP PF01042.21 AIM21733.1 - 1.2e-16 60.9 0.1 1.3e-16 60.7 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP APH_6_hur PF04655.14 AIM21734.1 - 2.4e-82 276.1 2.8 2.8e-82 275.9 2.8 1.0 1 0 0 1 1 1 1 Aminoglycoside/hydroxyurea antibiotic resistance kinase Fructosamin_kin PF03881.14 AIM21734.1 - 0.0018 17.5 0.0 0.0029 16.9 0.0 1.2 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 AIM21734.1 - 0.0073 16.3 9.2 0.0084 16.1 7.4 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Cupin_2 PF07883.11 AIM21735.1 - 3.3e-17 62.0 0.0 4.9e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 AIM21735.1 - 3.1e-06 27.1 0.0 4.2e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 AIM21735.1 - 2.7e-05 23.7 0.0 5.8e-05 22.7 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF861) Auxin_BP PF02041.16 AIM21735.1 - 0.0003 20.5 0.0 0.00085 19.0 0.0 1.7 1 1 0 1 1 1 1 Auxin binding protein Cupin_1 PF00190.22 AIM21735.1 - 0.011 15.3 0.0 0.034 13.7 0.0 1.7 1 1 0 1 1 1 0 Cupin EutQ PF06249.12 AIM21735.1 - 0.013 15.2 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ DMSP_lyase PF16867.5 AIM21735.1 - 0.017 14.7 0.0 0.032 13.9 0.0 1.4 1 1 0 1 1 1 0 Dimethlysulfonioproprionate lyase MannoseP_isomer PF01050.18 AIM21735.1 - 0.035 14.0 0.0 0.077 12.9 0.0 1.5 1 1 1 2 2 2 0 Mannose-6-phosphate isomerase BenE PF03594.13 AIM21736.1 - 2.2e-143 477.6 42.0 2.5e-143 477.4 42.0 1.0 1 0 0 1 1 1 1 Benzoate membrane transport protein HTH_3 PF01381.22 AIM21737.1 - 1.7e-15 56.8 0.0 2.4e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix Cupin_2 PF07883.11 AIM21737.1 - 7.5e-14 51.2 0.1 1.2e-13 50.5 0.1 1.3 1 0 0 1 1 1 1 Cupin domain HTH_31 PF13560.6 AIM21737.1 - 1.3e-11 44.7 0.2 2.2e-11 43.9 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 AIM21737.1 - 1.8e-06 27.7 0.0 3e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 AIM21737.1 - 0.0014 18.6 0.0 0.0021 18.0 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 AIM21737.1 - 0.011 15.6 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain AraC_binding PF02311.19 AIM21737.1 - 0.013 15.4 0.1 0.03 14.2 0.1 1.5 1 0 0 1 1 1 0 AraC-like ligand binding domain HTH_26 PF13443.6 AIM21737.1 - 0.019 15.4 0.0 0.032 14.7 0.0 1.4 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_23 PF13384.6 AIM21737.1 - 0.12 12.2 0.1 0.24 11.2 0.1 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Peptidase_S9 PF00326.21 AIM21738.1 - 1.7e-47 161.6 0.5 3e-47 160.8 0.5 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 AIM21738.1 - 8.7e-34 117.0 0.0 1.2e-25 90.2 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase, N-terminal beta-propeller domain Hydrolase_4 PF12146.8 AIM21738.1 - 0.025 13.8 0.1 1.1 8.5 0.0 2.3 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 AIM21738.1 - 0.028 14.5 0.0 0.058 13.5 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Esterase PF00756.20 AIM21738.1 - 0.047 13.3 2.2 0.042 13.5 0.5 1.8 2 0 0 2 2 2 0 Putative esterase PTR2 PF00854.21 AIM21739.1 - 2e-87 293.6 19.8 2.8e-87 293.1 19.8 1.1 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 AIM21739.1 - 1.4e-18 66.9 56.4 9.3e-14 51.1 40.0 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily HhH-GPD PF00730.25 AIM21740.1 - 8.5e-19 68.0 0.0 1.2e-18 67.5 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 AIM21740.1 - 1.7e-07 30.7 0.1 3.7e-07 29.7 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 AIM21740.1 - 7.4e-05 23.0 3.7 0.00012 22.3 3.7 1.4 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III Rnf-Nqr PF02508.14 AIM21741.1 - 4.6e-62 209.1 10.5 5.3e-62 208.9 10.5 1.0 1 0 0 1 1 1 1 Rnf-Nqr subunit, membrane protein FMN_bind PF04205.14 AIM21742.1 - 2.7e-18 66.3 0.0 5.1e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 FMN-binding domain NQR2_RnfD_RnfE PF03116.15 AIM21743.1 - 3.4e-108 361.5 13.7 3.9e-108 361.3 13.7 1.0 1 0 0 1 1 1 1 NQR2, RnfD, RnfE family ATPase_gene1 PF09527.10 AIM21743.1 - 0.0077 16.4 1.1 0.0077 16.4 1.1 3.8 4 2 0 4 4 4 1 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter DUF2826 PF11442.8 AIM21743.1 - 0.13 12.1 0.2 0.22 11.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2826) HTH_18 PF12833.7 AIM21744.1 - 1.8e-20 73.0 0.8 2.8e-20 72.4 0.8 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AIM21744.1 - 7.4e-16 57.8 0.1 3.8e-10 39.6 0.2 2.5 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family GyrI-like PF06445.15 AIM21744.1 - 2.7e-09 37.5 0.0 4.1e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 GyrI-like small molecule binding domain Complex1_51K PF01512.17 AIM21745.1 - 5.1e-47 159.5 0.2 1.2e-46 158.3 0.2 1.7 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit RnfC_N PF13375.6 AIM21745.1 - 2.6e-32 110.8 0.0 5.6e-32 109.7 0.0 1.6 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain SLBB PF10531.9 AIM21745.1 - 1.2e-11 44.3 0.2 2.5e-11 43.3 0.2 1.6 1 0 0 1 1 1 1 SLBB domain Fer4_10 PF13237.6 AIM21745.1 - 3.9e-10 39.7 16.2 5.2e-09 36.1 7.5 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 AIM21745.1 - 1.7e-09 37.1 13.2 7.2e-05 22.4 2.9 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 AIM21745.1 - 2.9e-09 37.4 5.6 1.2e-08 35.4 5.9 2.0 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 AIM21745.1 - 1.7e-08 34.7 6.5 6e-08 33.0 6.0 2.3 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 AIM21745.1 - 9.5e-08 32.1 7.0 3.5e-07 30.3 7.0 2.0 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 AIM21745.1 - 1.6e-07 31.8 9.5 2.3e-06 28.1 8.2 3.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AIM21745.1 - 3.3e-07 31.1 8.5 0.0051 17.7 1.1 3.6 3 0 0 3 3 2 2 4Fe-4S double cluster binding domain Fer4_2 PF12797.7 AIM21745.1 - 4.1e-07 29.7 14.0 0.00077 19.4 4.2 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 AIM21745.1 - 4.3e-06 26.6 15.4 0.00049 20.1 2.6 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.6 AIM21745.1 - 4.8e-06 26.7 4.3 0.023 14.9 0.1 2.8 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 AIM21745.1 - 9.7e-06 25.7 9.4 0.001 19.4 1.9 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain NQRA PF05896.11 AIM21745.1 - 0.00023 20.7 0.0 0.00087 18.8 0.0 1.9 1 1 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) Fer4_22 PF17179.4 AIM21745.1 - 0.00062 20.6 4.2 0.16 12.8 0.1 2.7 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 AIM21745.1 - 0.0014 18.7 10.3 0.0051 16.9 9.9 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_3 PF12798.7 AIM21745.1 - 0.0016 19.2 16.2 0.21 12.6 4.5 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_13 PF13370.6 AIM21745.1 - 2.2 8.9 18.3 1.9 9.1 3.1 4.3 3 0 0 3 3 2 0 4Fe-4S single cluster domain of Ferredoxin I Atg14 PF10186.9 AIM21745.1 - 6.9 5.6 8.6 11 5.0 8.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fer4_21 PF14697.6 AIM21746.1 - 4.2e-17 62.0 16.5 4.2e-17 62.0 16.5 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain FeS PF04060.13 AIM21746.1 - 5e-13 48.5 4.8 5e-13 48.5 4.8 2.4 2 0 0 2 2 1 1 Putative Fe-S cluster Fer4 PF00037.27 AIM21746.1 - 1.1e-11 44.1 27.8 3.8e-07 29.7 6.6 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_7 PF12838.7 AIM21746.1 - 1.1e-08 35.5 19.4 0.00055 20.5 1.9 2.9 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AIM21746.1 - 4.9e-08 33.0 33.2 1.7e-06 28.1 14.9 2.6 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_16 PF13484.6 AIM21746.1 - 3.9e-07 30.9 17.1 0.00022 22.1 2.6 3.1 3 0 0 3 3 3 2 4Fe-4S double cluster binding domain Fer4_2 PF12797.7 AIM21746.1 - 1.4e-06 28.0 21.3 4.6e-05 23.2 2.8 3.3 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_10 PF13237.6 AIM21746.1 - 2.5e-06 27.5 14.0 2.5e-06 27.5 14.0 3.1 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 AIM21746.1 - 8.3e-06 25.7 29.2 2e-05 24.5 5.9 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_3 PF12798.7 AIM21746.1 - 0.0066 17.3 4.7 0.0066 17.3 4.7 3.4 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_22 PF17179.4 AIM21746.1 - 0.019 15.8 0.3 0.019 15.8 0.3 2.6 3 0 0 3 3 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 AIM21746.1 - 0.021 15.3 23.8 0.084 13.4 3.0 3.4 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_17 PF13534.6 AIM21746.1 - 0.091 13.3 22.0 11 6.6 11.1 3.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 AIM21746.1 - 0.35 11.1 15.1 0.53 10.5 3.1 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 AIM21746.1 - 0.5 11.1 19.3 0.38 11.5 4.4 3.6 1 1 1 2 2 2 0 4Fe-4S single cluster domain Fer4_8 PF13183.6 AIM21746.1 - 4.6 7.8 24.5 7.9 7.0 4.9 3.0 1 1 2 3 3 3 0 4Fe-4S dicluster domain Rnf-Nqr PF02508.14 AIM21747.1 - 3.4e-60 203.0 22.7 3.8e-60 202.8 22.7 1.0 1 0 0 1 1 1 1 Rnf-Nqr subunit, membrane protein DUF2569 PF10754.9 AIM21748.1 - 1.4e-40 139.0 12.6 1.6e-40 138.9 12.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2569) DUF4271 PF14093.6 AIM21748.1 - 2.6 7.9 17.5 8.2 6.3 17.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4271) GFO_IDH_MocA PF01408.22 AIM21749.1 - 4e-24 85.7 0.0 6.7e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 AIM21749.1 - 1.9e-17 63.3 0.0 2.7e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.24 AIM21749.1 - 9.8e-05 22.8 0.0 0.00016 22.1 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_3 PF03447.16 AIM21749.1 - 0.00057 20.5 0.0 0.0011 19.7 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain AAA_33 PF13671.6 AIM21749.1 - 0.078 13.1 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain SBF_like PF13593.6 AIM21750.1 - 2e-103 346.0 27.6 2.3e-103 345.8 27.6 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) AAA_28 PF13521.6 AIM21751.1 - 9.8e-41 139.7 0.0 1.1e-40 139.5 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AIM21751.1 - 0.00022 20.9 0.0 0.00042 20.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.6 AIM21751.1 - 0.00033 21.2 0.0 0.00046 20.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 AIM21751.1 - 0.0028 18.2 0.0 0.0045 17.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter MeaB PF03308.16 AIM21751.1 - 0.0036 16.3 0.2 0.0056 15.7 0.2 1.4 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 AIM21751.1 - 0.0094 16.3 0.2 0.01 16.2 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain DAP3 PF10236.9 AIM21751.1 - 0.0095 15.1 0.0 0.013 14.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_17 PF13207.6 AIM21751.1 - 0.013 15.9 0.0 0.02 15.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 AIM21751.1 - 0.029 14.3 0.1 0.046 13.6 0.1 1.2 1 0 0 1 1 1 0 NTPase Zeta_toxin PF06414.12 AIM21751.1 - 0.03 13.6 0.0 0.051 12.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 AIM21751.1 - 0.032 14.0 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 AIM21751.1 - 0.033 14.5 0.0 0.052 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 AIM21751.1 - 0.036 14.2 0.0 0.038 14.1 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase Viral_helicase1 PF01443.18 AIM21751.1 - 0.041 13.6 0.1 0.056 13.2 0.1 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Ploopntkinase3 PF18751.1 AIM21751.1 - 0.052 13.5 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_33 PF13671.6 AIM21751.1 - 0.057 13.6 0.1 0.3 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 AIM21751.1 - 0.073 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 AIM21751.1 - 0.077 12.9 0.1 0.26 11.2 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 AIM21751.1 - 0.14 12.4 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AIM21751.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 AIM21751.1 - 0.18 10.9 0.0 0.32 10.1 0.0 1.3 2 0 0 2 2 2 0 G-protein alpha subunit T2SSE PF00437.20 AIM21751.1 - 0.24 10.4 0.0 0.35 9.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein A_deaminase PF00962.22 AIM21752.1 - 3.8e-93 312.4 0.0 4.3e-93 312.2 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase DeoRC PF00455.22 AIM21753.1 - 3.6e-42 144.0 1.7 4.6e-42 143.7 1.7 1.1 1 0 0 1 1 1 1 DeoR C terminal sensor domain HTH_DeoR PF08220.12 AIM21753.1 - 8.2e-17 60.7 0.1 1.5e-16 59.9 0.1 1.5 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain GntR PF00392.21 AIM21753.1 - 7.5e-07 28.7 0.4 2.4e-06 27.1 0.4 1.9 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_11 PF08279.12 AIM21753.1 - 1.2e-06 28.3 0.1 2.4e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 HTH domain HTH_28 PF13518.6 AIM21753.1 - 0.00034 20.7 0.1 0.00088 19.4 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain Put_DNA-bind_N PF06971.13 AIM21753.1 - 0.0016 18.4 0.1 0.0047 16.9 0.1 1.7 1 0 0 1 1 1 1 Putative DNA-binding protein N-terminus HTH_Crp_2 PF13545.6 AIM21753.1 - 0.0041 17.1 0.1 0.0094 15.9 0.1 1.7 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_5 PF01022.20 AIM21753.1 - 0.0042 16.9 0.2 0.0076 16.1 0.2 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_29 PF13551.6 AIM21753.1 - 0.0048 16.9 0.0 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix Rrf2 PF02082.20 AIM21753.1 - 0.0099 16.2 0.1 0.033 14.5 0.1 1.9 1 0 0 1 1 1 1 Transcriptional regulator DUF2250 PF10007.9 AIM21753.1 - 0.011 15.9 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) HTH_20 PF12840.7 AIM21753.1 - 0.011 15.8 0.2 0.042 13.9 0.2 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain MarR_2 PF12802.7 AIM21753.1 - 0.014 15.3 0.2 0.051 13.5 0.2 2.0 1 0 0 1 1 1 0 MarR family HTH_24 PF13412.6 AIM21753.1 - 0.02 14.4 0.2 0.048 13.2 0.2 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_12 PF08461.10 AIM21753.1 - 0.025 14.5 0.0 0.052 13.5 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain MarR PF01047.22 AIM21753.1 - 0.037 14.0 0.2 0.1 12.5 0.1 1.8 2 0 0 2 2 2 0 MarR family HTH_AsnC-type PF13404.6 AIM21753.1 - 0.037 13.9 0.4 0.086 12.7 0.1 1.9 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain RP-C PF03428.13 AIM21753.1 - 0.039 13.6 0.3 0.25 11.0 0.0 2.2 2 1 0 2 2 2 0 Replication protein C N-terminal domain HTH_IclR PF09339.10 AIM21753.1 - 0.041 13.7 0.3 0.1 12.4 0.3 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain TrmB PF01978.19 AIM21753.1 - 0.046 13.6 0.0 0.096 12.6 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Fe_dep_repress PF01325.19 AIM21753.1 - 0.049 13.8 0.0 0.099 12.9 0.0 1.6 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain FaeA PF04703.12 AIM21753.1 - 0.072 13.5 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 FaeA-like protein HycI PF01750.18 AIM21753.1 - 0.088 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Hydrogenase maturation protease HxlR PF01638.17 AIM21753.1 - 0.093 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 HxlR-like helix-turn-helix NUDIX PF00293.28 AIM21754.1 - 7.2e-05 22.8 0.1 8.6e-05 22.6 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain DUF4406 PF14359.6 AIM21755.1 - 0.03 14.8 0.0 0.043 14.3 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4406) Aminotran_1_2 PF00155.21 AIM21756.1 - 1.1e-56 192.6 0.0 1.3e-56 192.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 AIM21756.1 - 0.004 16.5 0.0 0.0059 15.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase LHC PF00556.20 AIM21756.1 - 0.029 14.6 0.0 0.076 13.2 0.0 1.8 1 0 0 1 1 1 0 Antenna complex alpha/beta subunit SANT_DAMP1_like PF16282.5 AIM21756.1 - 0.042 14.1 0.7 0.36 11.1 0.0 2.6 2 1 1 3 3 3 0 SANT/Myb-like domain of DAMP1 Cys_Met_Meta_PP PF01053.20 AIM21756.1 - 0.11 11.0 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme PTS_EIIC PF02378.18 AIM21757.1 - 1.2e-85 287.4 31.9 1.9e-85 286.8 31.9 1.3 1 0 0 1 1 1 1 Phosphotransferase system, EIIC PTS_EIIB PF00367.20 AIM21757.1 - 9.5e-16 57.0 0.2 2.2e-15 55.8 0.2 1.6 1 0 0 1 1 1 1 phosphotransferase system, EIIB TNFR_16_TM PF18422.1 AIM21757.1 - 0.028 14.4 0.1 0.094 12.7 0.1 1.9 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain Peripla_BP_1 PF00532.21 AIM21758.1 - 2.5e-58 197.7 0.0 3.5e-58 197.2 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_3 PF13377.6 AIM21758.1 - 1.8e-27 96.7 0.2 1.6e-26 93.6 0.1 2.4 2 1 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_4 PF13407.6 AIM21758.1 - 2e-18 66.9 0.0 2.2e-17 63.5 0.0 2.2 1 1 1 2 2 2 1 Periplasmic binding protein domain LacI PF00356.21 AIM21758.1 - 2.7e-18 65.5 0.4 4.9e-18 64.6 0.4 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family HTH_3 PF01381.22 AIM21758.1 - 1.6e-05 24.8 0.1 4.8e-05 23.3 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 AIM21758.1 - 0.0026 18.1 2.2 0.0063 16.8 0.0 2.7 3 0 0 3 3 2 1 Helix-turn-helix domain HTH_26 PF13443.6 AIM21758.1 - 0.01 16.2 0.0 0.019 15.4 0.0 1.5 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Peripla_BP_6 PF13458.6 AIM21758.1 - 0.012 15.3 0.1 0.045 13.4 0.0 2.0 2 0 0 2 2 2 0 Periplasmic binding protein HTH_Tnp_ISL3 PF13542.6 AIM21758.1 - 0.025 14.0 2.1 0.03 13.7 0.3 2.2 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 DRTGG PF07085.12 AIM21758.1 - 0.033 14.0 0.1 0.13 12.0 0.0 2.0 2 0 0 2 2 2 0 DRTGG domain YdaS_antitoxin PF15943.5 AIM21758.1 - 0.1 12.5 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT LysR_substrate PF03466.20 AIM21759.1 - 1.2e-35 122.8 3.3 1.2e-35 122.8 3.3 1.5 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AIM21759.1 - 1.3e-17 63.5 2.6 1.3e-17 63.5 2.6 2.0 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family DciA PF05258.12 AIM21759.1 - 0.017 15.5 0.1 10 6.6 0.1 2.6 2 0 0 2 2 2 0 Dna[CI] antecedent, DciA Sulphotransf PF09037.10 AIM21759.1 - 0.028 14.0 0.0 0.063 12.8 0.0 1.7 2 0 0 2 2 2 0 Stf0 sulphotransferase Beta-lactamase PF00144.24 AIM21760.1 - 3.1e-81 273.2 2.0 3.6e-81 273.0 2.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Mx_ML PF17536.2 AIM21760.1 - 0.21 11.3 0.0 0.4 10.4 0.0 1.3 1 0 0 1 1 1 0 Matrix and Matrix long proteins N-terminal HTH_1 PF00126.27 AIM21761.1 - 1.8e-23 82.2 0.2 3.1e-23 81.5 0.2 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 AIM21761.1 - 1.4e-17 63.8 0.2 2.1e-17 63.2 0.2 1.3 1 0 0 1 1 1 1 LysR substrate binding domain P22_Cro PF14549.6 AIM21761.1 - 0.00051 19.8 0.0 0.00096 19.0 0.0 1.4 1 0 0 1 1 1 1 DNA-binding transcriptional regulator Cro LPD22 PF18834.1 AIM21761.1 - 0.005 17.0 0.2 0.016 15.4 0.2 1.8 1 1 0 1 1 1 1 Large polyvalent protein associated domain 22 Beta-lactamase PF00144.24 AIM21762.1 - 5.4e-67 226.4 4.5 6.4e-67 226.1 4.5 1.0 1 0 0 1 1 1 1 Beta-lactamase DUF945 PF06097.11 AIM21763.1 - 1.6e-112 377.0 20.8 1.8e-112 376.8 20.8 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF945) Phage_tube PF04985.14 AIM21763.1 - 0.017 14.9 0.0 0.043 13.5 0.0 1.8 1 0 0 1 1 1 0 Phage tail tube protein FII P5CR_dimer PF14748.6 AIM21763.1 - 0.023 15.0 0.8 0.055 13.7 0.8 1.6 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation PMI_typeI PF01238.21 AIM21764.1 - 4e-100 335.6 0.0 5.9e-100 335.1 0.0 1.2 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 AIM21764.1 - 4.6e-05 23.1 0.0 0.0048 16.6 0.0 2.4 2 0 0 2 2 2 2 Cupin domain ABA_WDS PF02496.16 AIM21765.1 - 0.029 14.9 0.1 0.045 14.2 0.1 1.3 1 0 0 1 1 1 0 ABA/WDS induced protein SAP130_C PF16014.5 AIM21765.1 - 0.04 13.0 1.1 0.042 12.9 1.1 1.1 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus GoLoco PF02188.17 AIM21765.1 - 0.15 11.7 0.3 2.9 7.5 0.1 2.1 2 0 0 2 2 2 0 GoLoco motif Lyase_1 PF00206.20 AIM21766.1 - 1.5e-122 408.8 0.1 2.1e-122 408.4 0.1 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 AIM21766.1 - 4.8e-27 94.1 0.7 1.3e-26 92.7 0.3 2.0 2 0 0 2 2 2 1 Fumarase C C-terminus HTH_11 PF08279.12 AIM21767.1 - 3e-15 55.9 0.1 5.3e-15 55.1 0.1 1.4 1 0 0 1 1 1 1 HTH domain WYL PF13280.6 AIM21767.1 - 5.9e-15 55.7 0.9 8.9e-15 55.2 0.9 1.2 1 0 0 1 1 1 1 WYL domain HTH_DeoR PF08220.12 AIM21767.1 - 0.0016 18.1 0.0 0.0035 17.1 0.0 1.5 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_20 PF12840.7 AIM21767.1 - 0.024 14.7 0.9 0.11 12.5 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_IclR PF09339.10 AIM21767.1 - 0.62 9.9 4.9 0.17 11.7 1.6 1.7 2 0 0 2 2 2 0 IclR helix-turn-helix domain Glyoxalase PF00903.25 AIM21768.1 - 1.8e-08 34.6 0.0 2.3e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 AIM21768.1 - 0.053 14.3 0.0 0.5 11.2 0.0 2.0 1 1 0 1 1 1 0 Glyoxalase-like domain Ter PF05472.11 AIM21769.1 - 6.5e-137 455.5 3.5 7.3e-137 455.3 3.5 1.0 1 0 0 1 1 1 1 DNA replication terminus site-binding protein (Ter protein) Glyco_hydro_3 PF00933.21 AIM21770.1 - 3.1e-91 306.1 0.6 4e-91 305.7 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 AIM21770.1 - 3.6e-06 27.1 0.1 8.4e-06 25.9 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain GHL10 PF02638.15 AIM21771.1 - 4.7e-103 344.5 1.4 5.4e-103 344.3 1.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase-like 10 GHL6 PF14871.6 AIM21771.1 - 0.0021 18.2 0.0 0.51 10.5 0.0 3.1 1 1 0 1 1 1 1 Hypothetical glycosyl hydrolase 6 Melibiase PF02065.18 AIM21771.1 - 0.013 14.5 0.0 0.046 12.7 0.0 1.8 1 1 0 1 1 1 0 Melibiase Glyco_hydro_66 PF13199.6 AIM21771.1 - 0.015 14.0 0.1 0.018 13.7 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 66 GHL15 PF14885.6 AIM21771.1 - 0.072 13.0 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 15 MFS_1 PF07690.16 AIM21772.1 - 1.8e-42 145.6 59.0 1.8e-29 102.8 28.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AIM21772.1 - 1.1e-14 54.2 33.1 2.2e-10 40.0 12.2 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 AIM21772.1 - 7.6e-06 24.6 7.5 0.00035 19.1 2.0 2.3 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 AIM21772.1 - 0.00021 20.3 18.0 0.0004 19.4 9.4 3.0 2 1 1 3 3 3 2 MFS_1 like family BT1 PF03092.16 AIM21772.1 - 0.42 8.8 22.2 0.035 12.3 4.9 2.8 2 1 0 2 2 2 0 BT1 family DUF2614 PF11023.8 AIM21772.1 - 1.2 9.2 7.7 8.2 6.6 0.3 2.9 2 0 0 2 2 2 0 Zinc-ribbon containing domain LysR_substrate PF03466.20 AIM21773.1 - 1.5e-45 155.1 3.2 2.2e-45 154.6 3.2 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM21773.1 - 3.3e-22 78.2 2.9 3.6e-22 78.1 0.7 2.2 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_20 PF12840.7 AIM21773.1 - 0.041 13.9 0.1 0.12 12.5 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain ROK PF00480.20 AIM21774.1 - 4.7e-51 174.0 0.0 6.2e-51 173.6 0.0 1.1 1 0 0 1 1 1 1 ROK family Fe_dep_repress PF01325.19 AIM21774.1 - 0.00016 21.8 0.0 0.00035 20.7 0.0 1.5 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain MarR PF01047.22 AIM21774.1 - 0.00017 21.5 0.3 0.00047 20.0 0.0 1.8 2 0 0 2 2 2 1 MarR family MarR_2 PF12802.7 AIM21774.1 - 0.0017 18.2 0.7 0.011 15.6 0.1 2.5 3 0 0 3 3 3 1 MarR family HTH_24 PF13412.6 AIM21774.1 - 0.072 12.7 0.3 0.21 11.2 0.1 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding AAA_26 PF13500.6 AIM21775.1 - 3.8e-31 108.5 0.0 4.3e-31 108.3 0.0 1.0 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 AIM21775.1 - 1.6e-13 50.8 0.0 2.1e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF1611 PF07755.11 AIM21775.1 - 0.0083 15.4 0.2 0.025 13.9 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1611_C) P-loop domain DUF2938 PF11158.8 AIM21776.1 - 1.4e-50 170.7 5.7 1.7e-50 170.4 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2938) MerR PF00376.23 AIM21777.1 - 1.6e-10 40.6 0.2 3.1e-10 39.6 0.2 1.5 1 0 0 1 1 1 1 MerR family regulatory protein MerR_1 PF13411.6 AIM21777.1 - 4.4e-10 39.5 0.1 1e-09 38.4 0.0 1.6 2 0 0 2 2 2 1 MerR HTH family regulatory protein MerR-DNA-bind PF09278.11 AIM21777.1 - 2.5e-08 34.3 7.9 4.3e-08 33.6 7.9 1.4 1 0 0 1 1 1 1 MerR, DNA binding HTH_31 PF13560.6 AIM21777.1 - 0.011 16.0 1.3 0.26 11.7 0.3 2.6 1 1 1 2 2 2 0 Helix-turn-helix domain AbiEi_4 PF13338.6 AIM21777.1 - 0.026 14.7 1.4 0.037 14.2 0.2 1.9 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin HTH_3 PF01381.22 AIM21777.1 - 0.13 12.3 0.1 0.76 9.9 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix Voltage_CLC PF00654.20 AIM21778.1 - 3.4e-77 260.1 39.8 4.3e-77 259.7 39.8 1.2 1 0 0 1 1 1 1 Voltage gated chloride channel ABC_tran PF00005.27 AIM21780.1 - 1.8e-35 122.5 0.0 3.9e-35 121.3 0.0 1.6 1 0 0 1 1 1 1 ABC transporter CBS PF00571.28 AIM21780.1 - 2.7e-05 24.5 0.1 0.00064 20.1 0.0 2.6 2 0 0 2 2 2 1 CBS domain AAA_16 PF13191.6 AIM21780.1 - 2.9e-05 24.5 0.1 7.4e-05 23.2 0.1 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 AIM21780.1 - 9.2e-05 22.4 0.0 0.39 10.5 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 AIM21780.1 - 0.00018 21.9 0.4 0.0034 17.8 0.4 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 AIM21780.1 - 0.00043 20.1 0.0 0.00089 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 AIM21780.1 - 0.001 19.0 0.0 0.0023 17.9 0.0 1.6 2 0 0 2 2 1 1 Rad17 P-loop domain AAA_22 PF13401.6 AIM21780.1 - 0.0084 16.4 0.1 0.022 15.0 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 AIM21780.1 - 0.0097 15.5 0.0 0.11 12.0 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 AIM21780.1 - 0.013 15.3 0.2 0.08 12.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 AIM21780.1 - 0.031 14.2 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase G-alpha PF00503.20 AIM21780.1 - 0.034 13.3 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_19 PF13245.6 AIM21780.1 - 0.035 14.4 0.0 0.096 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain IF3_N PF05198.16 AIM21780.1 - 0.036 14.3 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 Translation initiation factor IF-3, N-terminal domain AAA_14 PF13173.6 AIM21780.1 - 0.041 13.9 0.0 0.08 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Adeno_IVa2 PF02456.15 AIM21780.1 - 0.045 12.5 0.1 0.069 11.9 0.1 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_5 PF07728.14 AIM21780.1 - 0.046 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 AIM21780.1 - 0.073 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 AIM21780.1 - 0.076 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRP54 PF00448.22 AIM21780.1 - 0.097 12.3 0.1 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_28 PF13521.6 AIM21780.1 - 0.13 12.5 0.5 0.5 10.6 0.4 2.0 2 0 0 2 2 2 0 AAA domain S1_2 PF13509.6 AIM21780.1 - 0.16 12.0 0.0 0.97 9.5 0.0 2.2 2 0 0 2 2 2 0 S1 domain ATPase_2 PF01637.18 AIM21780.1 - 0.17 11.8 0.1 0.46 10.4 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 AIM21780.1 - 0.17 12.4 0.2 0.35 11.3 0.1 1.5 2 0 0 2 2 1 0 AAA domain AAA_15 PF13175.6 AIM21780.1 - 0.19 11.4 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain BPD_transp_1 PF00528.22 AIM21781.1 - 4e-20 72.3 20.7 5.4e-20 71.9 20.7 1.2 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component DUF5326 PF17260.2 AIM21781.1 - 0.042 14.0 3.0 0.042 14.0 3.0 3.8 3 1 0 3 3 3 0 Family of unknown function (DUF5326) OpuAC PF04069.12 AIM21782.1 - 6.3e-63 212.8 1.1 7.1e-63 212.6 1.1 1.0 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system PAPS_reduct PF01507.19 AIM21782.1 - 0.11 12.5 0.8 0.3 11.1 0.4 1.9 2 1 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family BPD_transp_1 PF00528.22 AIM21783.1 - 9e-24 84.2 13.0 9e-24 84.2 13.0 1.8 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component FtsX PF02687.21 AIM21783.1 - 3.8 8.0 12.5 10 6.7 2.5 3.3 3 1 0 3 3 3 0 FtsX-like permease family DUF4231 PF14015.6 AIM21783.1 - 4.7 7.7 5.1 1.6 9.2 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) MFS_1 PF07690.16 AIM21784.1 - 3.5e-54 184.1 63.8 4.9e-52 177.0 62.3 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AIM21784.1 - 3.2e-14 52.7 38.7 5.9e-12 45.2 13.7 2.9 3 1 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 AIM21784.1 - 2.8e-05 22.7 12.7 5.3e-05 21.8 12.7 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 AIM21784.1 - 0.02 13.2 10.9 0.097 10.9 1.5 3.3 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF1161 PF06649.12 AIM21785.1 - 6.8e-27 93.4 0.7 8.8e-27 93.1 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1161) DUF1283 PF06932.11 AIM21786.1 - 1.3e-38 131.0 5.9 1.6e-38 130.7 5.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1283) UPF0060 PF02694.15 AIM21787.1 - 1e-42 144.7 10.7 1.2e-42 144.5 10.7 1.0 1 0 0 1 1 1 1 Uncharacterised BCR, YnfA/UPF0060 family adh_short PF00106.25 AIM21788.1 - 1.5e-54 184.5 0.0 1.9e-54 184.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AIM21788.1 - 1.8e-38 132.4 0.2 2.2e-38 132.2 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AIM21788.1 - 1.8e-14 54.0 0.1 2.5e-14 53.6 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AIM21788.1 - 2.3e-09 37.1 0.4 3.9e-09 36.3 0.4 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 AIM21788.1 - 3.6e-08 33.5 0.5 4.3e-08 33.3 0.5 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 AIM21788.1 - 6.6e-06 25.5 0.0 9.3e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.17 AIM21788.1 - 6.2e-05 23.5 0.1 0.00014 22.4 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DUF4226 PF10774.9 AIM21788.1 - 0.0016 18.7 0.6 0.0024 18.1 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4226) Sacchrp_dh_NADP PF03435.18 AIM21788.1 - 0.0058 16.9 0.2 0.0083 16.4 0.2 1.4 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain RmlD_sub_bind PF04321.17 AIM21788.1 - 0.032 13.3 0.1 0.063 12.4 0.1 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.13 AIM21788.1 - 0.037 13.6 0.2 0.061 12.9 0.2 1.3 1 0 0 1 1 1 0 NmrA-like family GDP_Man_Dehyd PF16363.5 AIM21788.1 - 0.038 13.4 0.1 0.064 12.6 0.1 1.5 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Glyco_hydro_101 PF12905.7 AIM21788.1 - 0.045 13.2 0.0 0.099 12.0 0.0 1.5 2 0 0 2 2 2 0 Endo-alpha-N-acetylgalactosaminidase Lig_C PF18330.1 AIM21788.1 - 0.21 11.6 0.6 0.4 10.7 0.6 1.5 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region Acetyltransf_3 PF13302.7 AIM21789.1 - 1.5e-19 71.0 0.0 1.7e-19 70.8 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AIM21789.1 - 5.2e-07 29.9 0.0 7.1e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 AIM21789.1 - 1.8e-05 24.6 0.0 2.7e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 AIM21789.1 - 0.001 19.4 0.0 0.0015 18.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AIM21789.1 - 0.092 12.7 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TonB_dep_Rec PF00593.24 AIM21790.1 - 3.5e-50 172.2 39.5 5.3e-50 171.6 39.5 1.3 1 0 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AIM21790.1 - 1.4e-19 70.7 0.4 3.3e-19 69.5 0.4 1.7 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain STN PF07660.14 AIM21790.1 - 1.4e-10 40.8 0.1 4.6e-10 39.1 0.1 2.0 1 0 0 1 1 1 1 Secretin and TonB N terminus short domain OMP_b-brl_3 PF14905.6 AIM21790.1 - 4.3e-08 32.5 8.1 8.9e-06 24.9 3.4 2.5 2 1 0 2 2 2 2 Outer membrane protein beta-barrel family FecR PF04773.13 AIM21791.1 - 4.1e-16 59.4 0.0 6.9e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 FecR protein DUF4880 PF16220.5 AIM21791.1 - 1.2e-09 37.9 20.3 1.2e-09 37.9 20.3 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF4880) Sigma70_r4_2 PF08281.12 AIM21792.1 - 1.5e-15 56.6 0.0 3.6e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 AIM21792.1 - 5.7e-13 48.4 1.3 8.3e-13 47.9 1.3 1.3 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_ECF PF07638.11 AIM21792.1 - 2.3e-06 27.6 0.1 5.3e-06 26.5 0.1 1.5 1 1 0 1 1 1 1 ECF sigma factor Sigma70_r4 PF04545.16 AIM21792.1 - 9.3e-06 25.1 0.0 2.1e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 AIM21792.1 - 0.00056 19.6 0.1 0.0033 17.2 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.15 AIM21792.1 - 0.0052 16.8 0.1 0.11 12.6 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_24 PF13412.6 AIM21792.1 - 0.0059 16.1 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_38 PF13936.6 AIM21792.1 - 0.013 15.2 0.0 0.035 13.9 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_4 PF13613.6 AIM21792.1 - 0.017 14.8 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_31 PF13560.6 AIM21792.1 - 0.04 14.2 0.3 0.19 12.1 0.0 2.3 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_36 PF13730.6 AIM21792.1 - 0.046 13.7 0.0 0.086 12.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain TnsD PF15978.5 AIM21792.1 - 0.063 12.3 0.0 0.092 11.7 0.0 1.2 1 0 0 1 1 1 0 Tn7-like transposition protein D GerE PF00196.19 AIM21792.1 - 0.12 12.0 0.2 0.25 10.9 0.0 1.6 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family HTH_28 PF13518.6 AIM21792.1 - 0.12 12.6 0.4 1.2 9.3 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain DUF1118 PF06549.12 AIM21792.1 - 0.12 12.7 0.1 0.21 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1118) Amidohydro_1 PF01979.20 AIM21793.1 - 9.9e-72 242.1 0.0 1.2e-71 241.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AIM21793.1 - 3.5e-16 59.7 0.0 2.3e-12 47.2 0.0 2.5 3 0 0 3 3 3 2 Amidohydrolase family Peripla_BP_1 PF00532.21 AIM21793.1 - 0.072 12.5 0.0 0.099 12.1 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family HD_assoc PF13286.6 AIM21794.1 - 1.1e-23 83.6 0.0 4.8e-23 81.5 0.0 1.9 2 0 0 2 2 2 1 Phosphohydrolase-associated domain Peptidase_M3 PF01432.20 AIM21795.1 - 3.7e-140 468.2 3.2 5e-140 467.8 3.2 1.2 1 0 0 1 1 1 1 Peptidase family M3 TAP35_44 PF07265.11 AIM21795.1 - 0.019 15.0 0.2 0.085 12.9 0.1 2.1 2 0 0 2 2 2 0 Tapetum specific protein TAP35/TAP44 LysR_substrate PF03466.20 AIM21796.1 - 7.9e-36 123.4 13.3 1.1e-35 122.9 13.3 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM21796.1 - 0.00039 20.3 1.2 0.00081 19.3 0.2 2.1 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family PBP_like PF12727.7 AIM21796.1 - 0.11 11.6 0.0 0.26 10.4 0.0 1.7 2 0 0 2 2 2 0 PBP superfamily domain TauE PF01925.19 AIM21797.1 - 9.7e-29 100.7 33.6 1.2e-28 100.4 33.6 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE DUF412 PF04217.13 AIM21797.1 - 0.12 12.3 0.9 0.22 11.4 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF412 B12D PF06522.11 AIM21797.1 - 1.2 9.0 3.1 28 4.6 0.1 2.5 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit EMC3_TMCO1 PF01956.16 AIM21798.1 - 0.0057 16.4 0.4 0.0071 16.1 0.4 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like DUF4288 PF14119.6 AIM21798.1 - 0.013 15.8 0.0 0.017 15.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4288) Scs3p PF10261.9 AIM21798.1 - 0.017 14.6 0.1 0.02 14.4 0.1 1.0 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM RasGAP_C PF03836.15 AIM21798.1 - 0.027 14.6 0.3 0.037 14.2 0.3 1.1 1 0 0 1 1 1 0 RasGAP C-terminus DpnD-PcfM PF14207.6 AIM21798.1 - 0.049 13.5 0.1 0.096 12.6 0.1 1.5 1 0 0 1 1 1 0 DpnD/PcfM-like protein HlyD_3 PF13437.6 AIM21799.1 - 1.1e-17 64.7 8.0 4.5e-14 53.0 0.4 3.4 2 1 0 3 3 3 2 HlyD family secretion protein HlyD_D23 PF16576.5 AIM21799.1 - 5.2e-12 45.4 3.6 8.2e-08 31.7 0.4 2.3 2 0 0 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD PF00529.20 AIM21799.1 - 3.3e-11 42.9 0.1 4.2e-11 42.6 0.1 1.1 1 0 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl_2 PF13533.6 AIM21799.1 - 4.1e-08 32.9 10.0 0.00047 19.9 0.8 3.2 3 0 0 3 3 3 2 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AIM21799.1 - 0.00027 20.7 0.8 0.58 10.0 0.2 2.7 2 0 0 2 2 2 2 Biotin-requiring enzyme DraK_HK_N PF18092.1 AIM21799.1 - 0.076 13.5 1.5 0.19 12.2 0.5 2.2 2 0 0 2 2 2 0 DraK Histidine Kinase N-terminal domain ABC_membrane PF00664.23 AIM21800.1 - 7.6e-45 153.7 14.3 1e-44 153.3 14.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region Peptidase_C39 PF03412.15 AIM21800.1 - 2.5e-38 130.9 0.0 5.2e-38 129.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase C39 family ABC_tran PF00005.27 AIM21800.1 - 2.9e-32 112.0 0.0 4.9e-32 111.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AIM21800.1 - 3.7e-07 29.8 0.4 5e-05 22.8 0.1 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain Peptidase_C70 PF12385.8 AIM21800.1 - 6.5e-06 26.2 0.0 1.6e-05 25.0 0.0 1.6 1 1 0 1 1 1 1 Papain-like cysteine protease AvrRpt2 AAA_21 PF13304.6 AIM21800.1 - 5.9e-05 23.0 0.0 0.015 15.1 0.0 2.2 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AIM21800.1 - 6.7e-05 22.5 0.0 0.00016 21.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 AIM21800.1 - 0.00013 22.4 0.2 0.0039 17.6 0.2 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 AIM21800.1 - 0.0037 17.8 0.0 0.0064 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AIM21800.1 - 0.0078 16.5 0.6 0.084 13.2 0.6 2.3 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AIM21800.1 - 0.011 15.4 0.1 0.027 14.2 0.1 1.5 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 AIM21800.1 - 0.012 15.0 0.0 0.03 13.7 0.0 1.5 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI SbcCD_C PF13558.6 AIM21800.1 - 0.013 15.7 0.2 0.16 12.2 0.2 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Guanylate_cyc_2 PF09778.9 AIM21800.1 - 0.013 14.9 0.1 0.032 13.6 0.1 1.7 2 0 0 2 2 1 0 Guanylylate cyclase RsgA_GTPase PF03193.16 AIM21800.1 - 0.017 15.1 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 AIM21800.1 - 0.017 15.5 0.2 0.052 13.9 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 AIM21800.1 - 0.03 14.4 0.1 0.057 13.5 0.1 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Peptidase_C39_2 PF13529.6 AIM21800.1 - 0.053 14.1 0.0 0.14 12.7 0.0 1.7 1 0 0 1 1 1 0 Peptidase_C39 like family DUF87 PF01935.17 AIM21800.1 - 0.07 13.2 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_14 PF13173.6 AIM21800.1 - 0.082 12.9 0.0 1.4 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 AIM21800.1 - 0.13 11.9 0.1 0.28 10.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 AIM21800.1 - 0.14 11.4 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 AIM21800.1 - 0.14 12.6 0.0 0.33 11.4 0.0 1.6 2 0 0 2 2 1 0 RNA helicase AAA_33 PF13671.6 AIM21800.1 - 0.16 12.1 0.1 0.32 11.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 AIM21800.1 - 0.19 11.6 0.0 0.41 10.5 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain Peptidase_S58 PF03576.14 AIM21801.1 - 2e-98 329.6 0.0 2.4e-98 329.4 0.0 1.0 1 0 0 1 1 1 1 Peptidase family S58 Peptidase_M55 PF04951.13 AIM21802.1 - 1.2e-92 310.0 0.1 1.4e-92 309.9 0.1 1.0 1 0 0 1 1 1 1 D-aminopeptidase Ald_Xan_dh_C2 PF02738.18 AIM21803.1 - 5.5e-52 176.9 5.7 9.1e-22 77.2 0.0 3.1 2 1 1 3 3 3 3 Molybdopterin-binding domain of aldehyde dehydrogenase DUF4369 PF14289.6 AIM21803.1 - 0.008 16.7 0.0 0.2 12.2 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4369) Fer2_2 PF01799.20 AIM21804.1 - 1.5e-24 85.8 0.4 1.5e-24 85.8 0.4 1.7 2 0 0 2 2 2 1 [2Fe-2S] binding domain Fer2 PF00111.27 AIM21804.1 - 3.1e-06 27.0 0.0 3.1e-06 27.0 0.0 2.1 2 1 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 AIM21804.1 - 8.4e-06 25.8 0.1 1.3e-05 25.1 0.1 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 AIM21804.1 - 0.002 18.1 2.9 0.0025 17.8 0.5 2.4 3 1 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain DHODB_Fe-S_bind PF10418.9 AIM21804.1 - 1 9.2 8.9 0.11 12.3 4.1 2.0 2 0 0 2 2 2 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Cytochrome_CBB3 PF13442.6 AIM21805.1 - 4.5e-19 68.5 2.5 1.1e-08 35.2 0.0 3.5 3 1 0 3 3 3 3 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AIM21805.1 - 1.8e-18 67.5 0.0 1.5e-06 29.3 0.0 3.6 3 1 0 3 3 3 3 Cytochrome c Paired_CXXCH_1 PF09699.10 AIM21805.1 - 0.0024 17.6 2.6 4.7 7.0 0.0 3.4 3 0 0 3 3 3 2 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrome_C7 PF14522.6 AIM21805.1 - 0.0055 16.7 0.1 15 5.7 0.0 3.2 3 0 0 3 3 3 1 Cytochrome c7 and related cytochrome c GSu_C4xC__C2xCH PF09698.10 AIM21805.1 - 0.024 15.4 4.6 2.9 8.7 0.1 3.7 3 0 0 3 3 3 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) Cytochrom_C550 PF14495.6 AIM21805.1 - 3.9 7.2 4.6 1.5 8.5 0.0 2.8 4 1 1 5 5 5 0 Cytochrome c-550 domain Cupin_1 PF00190.22 AIM21806.1 - 1.6e-46 157.7 0.0 9.2e-24 83.8 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 AIM21806.1 - 3.4e-21 74.7 2.9 1.4e-09 37.5 0.4 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 AIM21806.1 - 1.9e-06 27.5 0.1 0.00038 20.1 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) TAT_signal PF10518.9 AIM21806.1 - 4.6e-05 23.1 0.9 4.6e-05 23.1 0.9 1.9 2 0 0 2 2 2 1 TAT (twin-arginine translocation) pathway signal sequence Cupin_4 PF08007.12 AIM21806.1 - 0.0035 16.9 0.0 0.011 15.2 0.0 1.7 2 0 0 2 2 2 1 Cupin superfamily protein MannoseP_isomer PF01050.18 AIM21806.1 - 0.0058 16.5 0.0 0.16 11.8 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase Cupin_8 PF13621.6 AIM21806.1 - 0.028 14.1 0.0 0.52 10.0 0.0 2.5 2 1 0 2 2 2 0 Cupin-like domain LysR_substrate PF03466.20 AIM21807.1 - 8.3e-41 139.7 7.1 8.3e-41 139.7 7.1 1.4 1 1 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM21807.1 - 1.7e-20 72.7 0.5 4.5e-20 71.4 0.5 1.8 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family SBP_bac_11 PF13531.6 AIM21807.1 - 0.0081 15.9 0.0 0.025 14.3 0.0 1.9 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein Chromate_transp PF02417.15 AIM21808.1 - 1.8e-29 102.9 14.9 2e-29 102.7 14.9 1.0 1 0 0 1 1 1 1 Chromate transporter Chromate_transp PF02417.15 AIM21809.1 - 1.6e-32 112.8 12.8 1.8e-32 112.7 12.8 1.0 1 0 0 1 1 1 1 Chromate transporter Inh PF02974.14 AIM21810.1 - 1e-16 60.8 0.0 1.2e-16 60.5 0.0 1.0 1 0 0 1 1 1 1 Protease inhibitor Inh ASH PF15780.5 AIM21810.1 - 0.099 12.9 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Phage_GPA PF05840.13 AIM21810.1 - 0.24 10.5 0.0 0.35 9.9 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) Peptidase_M10_C PF08548.11 AIM21811.1 - 2.4e-66 223.3 18.6 6.9e-66 221.8 18.6 1.8 1 1 0 1 1 1 1 Peptidase M10 serralysin C terminal HemolysinCabind PF00353.19 AIM21811.1 - 1.1e-11 44.5 26.1 2.5e-07 30.5 9.5 4.4 3 2 1 4 4 4 2 RTX calcium-binding nonapeptide repeat (4 copies) Peptidase_M10 PF00413.24 AIM21811.1 - 4.3e-11 42.9 2.3 2.1e-10 40.7 0.1 2.6 3 0 0 3 3 3 1 Matrixin Reprolysin_4 PF13583.6 AIM21811.1 - 0.00016 21.4 1.4 0.00039 20.1 1.4 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M43 PF05572.13 AIM21811.1 - 0.00021 21.2 0.4 0.00057 19.8 0.4 1.7 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 AIM21811.1 - 0.00022 21.7 0.7 0.00092 19.7 0.7 2.1 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 AIM21811.1 - 0.00046 20.4 1.9 0.0012 19.0 1.9 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M66 PF10462.9 AIM21811.1 - 0.0013 17.8 0.3 0.0027 16.7 0.3 1.4 1 0 0 1 1 1 1 Peptidase M66 DUF4953 PF16313.5 AIM21811.1 - 0.0027 17.0 1.4 0.0054 16.0 0.2 2.0 2 0 0 2 2 2 1 Met-zincin Astacin PF01400.24 AIM21811.1 - 0.18 11.4 1.2 1.4 8.5 0.0 2.4 3 0 0 3 3 3 0 Astacin (Peptidase family M12A) RibD_C PF01872.17 AIM21812.1 - 2e-27 96.3 0.0 2.8e-27 95.9 0.0 1.2 1 0 0 1 1 1 1 RibD C-terminal domain Abhydrolase_1 PF00561.20 AIM21813.1 - 1.3e-20 74.2 0.1 1.9e-19 70.3 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AIM21813.1 - 1.4e-19 71.6 0.1 1.8e-19 71.3 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AIM21813.1 - 7.4e-17 61.4 0.0 2.1e-16 59.9 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 AIM21813.1 - 2.9e-07 29.5 0.0 7.6e-07 28.1 0.0 1.6 2 0 0 2 2 2 1 Ndr family DUF1057 PF06342.12 AIM21813.1 - 5.6e-06 25.6 0.0 7.7e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Chlorophyllase2 PF12740.7 AIM21813.1 - 0.0004 19.4 0.0 0.00075 18.5 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 AIM21813.1 - 0.011 14.8 0.0 0.024 13.7 0.0 1.5 1 1 0 1 1 1 0 Chlorophyllase DUF915 PF06028.11 AIM21813.1 - 0.013 14.9 0.1 0.02 14.2 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DUF3530 PF12048.8 AIM21813.1 - 0.013 15.0 0.1 0.027 13.9 0.1 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3530) UPF0227 PF05728.12 AIM21813.1 - 0.023 14.7 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) PGAP1 PF07819.13 AIM21813.1 - 0.041 13.6 0.0 0.063 13.0 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_3 PF07859.13 AIM21813.1 - 0.084 12.7 0.0 0.18 11.6 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold DcrB PF08786.11 AIM21814.1 - 1.8e-33 115.3 0.0 2.1e-33 115.2 0.0 1.0 1 0 0 1 1 1 1 DcrB RHS_repeat PF05593.14 AIM21815.1 - 1.9e-59 197.5 95.4 2e-11 44.1 5.1 20.1 14 5 7 21 21 21 17 RHS Repeat PAAR_motif PF05488.13 AIM21815.1 - 6.4e-17 61.5 1.0 6.4e-17 61.5 1.0 2.7 2 1 1 3 3 3 1 PAAR motif RHS PF03527.14 AIM21815.1 - 7.5e-15 54.4 8.7 9.8e-13 47.6 0.4 5.5 4 0 0 4 4 4 2 RHS protein DUF4150 PF13665.6 AIM21815.1 - 0.096 12.8 0.1 24 5.1 0.0 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4150) IncD PF17628.2 AIM21815.1 - 5.2 6.8 9.4 13 5.6 9.4 1.5 1 0 0 1 1 1 0 Inclusion membrane protein D DUF4974 PF16344.5 AIM21818.1 - 0.064 13.3 0.0 0.17 11.9 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4974) NtCtMGAM_N PF16863.5 AIM21819.1 - 0.054 13.7 0.1 0.078 13.2 0.1 1.2 1 0 0 1 1 1 0 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase PhzC-PhzF PF02567.16 AIM21820.1 - 3.6e-55 187.4 0.0 4.3e-55 187.2 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.11 AIM21820.1 - 2.4e-06 26.8 0.0 3.7e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Proline racemase EamA PF00892.20 AIM21821.1 - 8.4e-26 90.8 34.8 1.2e-14 54.6 13.4 2.1 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.6 AIM21821.1 - 1e-05 25.3 10.8 2.7e-05 23.9 10.1 1.8 1 1 1 2 2 2 1 Putative multidrug resistance efflux transporter HTH_18 PF12833.7 AIM21822.1 - 7.7e-24 83.8 2.5 2e-23 82.4 2.5 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 AIM21822.1 - 3.3e-21 74.8 0.8 1.5e-09 37.7 0.1 3.1 3 0 0 3 3 3 2 Bacterial regulatory helix-turn-helix proteins, AraC family Glyoxalase_2 PF12681.7 AIM21823.1 - 0.00082 19.3 0.0 0.014 15.3 0.0 2.0 2 0 0 2 2 2 1 Glyoxalase-like domain Glyoxalase PF00903.25 AIM21823.1 - 0.0062 16.7 0.0 0.16 12.2 0.0 2.1 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 AIM21823.1 - 0.012 16.3 0.1 0.018 15.8 0.1 1.2 1 0 0 1 1 1 0 Glyoxalase-like domain CD4-extracel PF09191.10 AIM21823.1 - 0.095 13.1 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 CD4, extracellular MoaF PF10703.9 AIM21824.1 - 7.7e-06 25.8 0.2 1e-05 25.4 0.2 1.1 1 0 0 1 1 1 1 MoaF N-terminal domain MoaF_C PF17409.2 AIM21824.1 - 0.021 14.5 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 MoaF C-terminal domain SnoaL_2 PF12680.7 AIM21825.1 - 5.6e-12 46.2 0.0 7e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 AIM21825.1 - 2.1e-11 43.7 0.4 1.3e-10 41.1 0.4 1.9 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase DUF5065 PF16723.5 AIM21825.1 - 0.069 13.2 1.0 0.24 11.5 0.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5065) MFS_1 PF07690.16 AIM21826.1 - 1.3e-52 178.9 51.3 3.5e-31 108.4 23.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AIM21826.1 - 8e-16 57.9 29.4 2.4e-09 36.6 9.3 2.8 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 AIM21826.1 - 2.6e-10 39.7 21.3 1.5e-05 24.0 0.2 2.9 1 1 2 3 3 3 3 MFS_1 like family MFS_4 PF06779.14 AIM21826.1 - 0.0047 16.3 32.1 0.056 12.7 10.0 2.9 2 1 1 3 3 3 2 Uncharacterised MFS-type transporter YbfB MarR PF01047.22 AIM21827.1 - 1.8e-09 37.4 0.0 3.7e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 AIM21827.1 - 2.3e-09 37.0 0.8 6.3e-09 35.6 0.8 1.8 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 AIM21827.1 - 7e-09 36.1 0.7 1.6e-08 34.9 0.1 1.9 2 0 0 2 2 2 1 Winged helix DNA-binding domain HxlR PF01638.17 AIM21827.1 - 0.00073 19.3 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 HxlR-like helix-turn-helix PadR PF03551.14 AIM21827.1 - 0.014 15.3 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family HTH_34 PF13601.6 AIM21827.1 - 0.043 14.0 0.0 0.087 13.0 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain EAP30 PF04157.16 AIM21827.1 - 0.067 12.5 0.1 0.067 12.5 0.1 1.5 2 0 0 2 2 2 0 EAP30/Vps36 family HTH_24 PF13412.6 AIM21827.1 - 0.077 12.6 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding YjcB PF15940.5 AIM21828.1 - 3.1e-36 123.4 8.0 3.4e-36 123.3 8.0 1.0 1 0 0 1 1 1 1 Family of unknown function Transpeptidase PF00905.22 AIM21829.1 - 9.1e-74 248.4 0.0 1.3e-73 247.9 0.0 1.2 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain PBP_dimer PF03717.15 AIM21829.1 - 2.5e-46 158.3 0.2 5.3e-46 157.2 0.1 1.6 2 0 0 2 2 2 1 Penicillin-binding Protein dimerisation domain Transpeptidase PF00905.22 AIM21830.1 - 6.5e-70 235.8 0.0 8.2e-70 235.4 0.0 1.1 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain PBP_dimer PF03717.15 AIM21830.1 - 4.1e-18 66.4 0.8 5.8e-17 62.6 0.8 2.1 1 1 0 1 1 1 1 Penicillin-binding Protein dimerisation domain MCPsignal PF00015.21 AIM21831.1 - 8.5e-36 123.4 17.1 1.1e-34 119.8 14.4 2.4 2 0 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain TarH PF02203.15 AIM21831.1 - 5e-25 88.4 5.2 5e-25 88.4 5.2 3.4 4 0 0 4 4 4 1 Tar ligand binding domain homologue HAMP PF00672.25 AIM21831.1 - 2.1e-06 28.0 0.4 2.1e-06 28.0 0.4 3.3 3 0 0 3 3 3 1 HAMP domain DUF1366 PF07104.11 AIM21831.1 - 0.022 14.4 0.6 12 5.7 0.2 3.5 2 1 0 3 3 3 0 Protein of unknown function (DUF1366) DUF948 PF06103.11 AIM21831.1 - 1 9.6 19.8 1.4 9.2 0.2 4.8 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) KASH_CCD PF14662.6 AIM21831.1 - 3.5 7.4 8.3 0.44 10.3 1.4 2.8 2 2 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH Noelin-1 PF12308.8 AIM21831.1 - 3.9 7.5 7.9 1.1 9.2 0.4 3.2 3 1 0 4 4 4 0 Neurogenesis glycoprotein DASH_Dad2 PF08654.10 AIM21831.1 - 7.9 7.0 7.8 6.8 7.2 0.8 3.5 2 2 0 2 2 2 0 DASH complex subunit Dad2 Rick_17kDa_Anti PF05433.15 AIM21832.1 - 1.3e-08 34.6 16.7 2e-08 34.0 16.7 1.3 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 AIM21832.1 - 4.2e-05 23.5 16.2 0.0055 16.7 19.2 2.2 1 1 1 2 2 2 2 Glycine zipper Gly-zipper_YMGG PF13441.6 AIM21832.1 - 0.00011 21.9 17.8 0.29 10.9 4.3 2.2 1 1 0 1 1 1 1 YMGG-like Gly-zipper Gly-zipper_OmpA PF13436.6 AIM21832.1 - 0.0077 16.0 20.1 0.028 14.2 20.1 1.9 1 1 0 1 1 1 1 Glycine-zipper domain NTP_transf_9 PF04248.12 AIM21833.1 - 6.8e-31 106.0 0.0 9.2e-31 105.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF427) Rrf2 PF02082.20 AIM21834.1 - 9e-25 86.8 0.1 1.5e-24 86.2 0.1 1.3 1 0 0 1 1 1 1 Transcriptional regulator HrcA_DNA-bdg PF03444.15 AIM21834.1 - 0.00016 21.2 0.0 0.00024 20.7 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix transcription repressor, HrcA DNA-binding HTH_Crp_2 PF13545.6 AIM21834.1 - 0.0014 18.5 0.4 0.016 15.2 0.0 2.2 2 1 0 2 2 2 1 Crp-like helix-turn-helix domain TFIIE_alpha PF02002.17 AIM21834.1 - 0.022 14.6 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 TFIIE alpha subunit HTH_38 PF13936.6 AIM21834.1 - 0.052 13.3 0.2 0.17 11.7 0.1 1.9 1 1 1 2 2 2 0 Helix-turn-helix domain MarR_2 PF12802.7 AIM21834.1 - 0.053 13.4 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 MarR family HTH_IclR PF09339.10 AIM21834.1 - 0.066 13.0 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain Put_DNA-bind_N PF06971.13 AIM21834.1 - 0.094 12.7 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus HTH_24 PF13412.6 AIM21834.1 - 0.15 11.7 0.2 0.45 10.1 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding AcrZ PF10766.9 AIM21835.1 - 1.1e-21 76.1 3.9 1.2e-21 76.0 3.9 1.0 1 0 0 1 1 1 1 Multidrug efflux pump-associated protein AcrZ ABC_tran PF00005.27 AIM21836.1 - 8.5e-36 123.5 0.1 1.2e-35 123.0 0.1 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIM21836.1 - 2.7e-14 53.7 0.1 9.4e-07 28.9 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIM21836.1 - 3.4e-11 43.0 0.0 4.8e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 AIM21836.1 - 2.3e-07 30.0 1.8 0.014 14.2 0.1 3.2 2 1 0 2 2 2 2 Predicted ATPase of the ABC class AAA_23 PF13476.6 AIM21836.1 - 5.7e-05 23.7 1.3 0.00011 22.8 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 AIM21836.1 - 8.1e-05 22.3 0.1 0.00016 21.4 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AIM21836.1 - 8.4e-05 23.0 0.6 0.00015 22.2 0.6 1.6 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AIM21836.1 - 0.00023 21.1 0.1 0.00049 20.0 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 AIM21836.1 - 0.00075 19.8 0.7 0.005 17.1 0.7 2.1 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 AIM21836.1 - 0.0012 18.5 1.2 0.006 16.2 1.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_13 PF13166.6 AIM21836.1 - 0.0013 17.5 0.0 0.32 9.6 0.0 2.2 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 AIM21836.1 - 0.0015 18.5 0.1 0.0074 16.2 0.0 1.9 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_30 PF13604.6 AIM21836.1 - 0.0031 17.3 0.2 0.0082 15.9 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AIM21836.1 - 0.0082 16.3 0.2 0.015 15.5 0.2 1.7 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 AIM21836.1 - 0.01 15.6 0.0 0.11 12.2 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain SbcCD_C PF13558.6 AIM21836.1 - 0.025 14.8 0.3 0.92 9.8 0.1 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA PF00004.29 AIM21836.1 - 0.033 14.6 0.1 0.8 10.1 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 AIM21836.1 - 0.051 13.2 0.1 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain CobU PF02283.16 AIM21836.1 - 0.052 13.1 0.3 1.4 8.5 0.0 2.4 2 1 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase NACHT PF05729.12 AIM21836.1 - 0.054 13.4 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 AIM21836.1 - 0.058 13.9 0.1 0.14 12.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.20 AIM21836.1 - 0.071 13.0 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Adenylylsulphate kinase Adeno_IVa2 PF02456.15 AIM21836.1 - 0.11 11.3 0.3 0.28 9.9 0.1 1.6 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_28 PF13521.6 AIM21836.1 - 0.14 12.4 0.8 0.66 10.2 0.2 2.3 1 1 2 3 3 3 0 AAA domain AAA_14 PF13173.6 AIM21836.1 - 0.16 12.0 0.1 2.5 8.1 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 AIM21836.1 - 0.18 11.5 0.4 0.59 9.8 0.1 2.0 2 0 0 2 2 2 0 AAA domain BPD_transp_1 PF00528.22 AIM21837.1 - 5.3e-23 81.7 14.9 5.3e-23 81.7 14.9 1.6 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component SBP_bac_3 PF00497.20 AIM21838.1 - 3e-41 141.3 0.0 4.2e-41 140.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 AIM21838.1 - 0.066 13.4 0.0 0.25 11.5 0.0 1.9 1 1 0 1 1 1 0 Ligated ion channel L-glutamate- and glycine-binding site Bac_luciferase PF00296.20 AIM21839.1 - 8.4e-56 189.7 5.8 1.1e-55 189.3 5.8 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase DUF3726 PF12525.8 AIM21839.1 - 0.026 14.6 0.0 0.069 13.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3726) MmgE_PrpD PF03972.14 AIM21840.1 - 1.4e-69 234.8 8.5 6.1e-69 232.7 8.5 1.7 1 1 0 1 1 1 1 MmgE/PrpD family DAP10 PF07213.11 AIM21840.1 - 0.11 12.5 0.2 0.34 10.9 0.2 1.8 1 0 0 1 1 1 0 DAP10 membrane protein LysR_substrate PF03466.20 AIM21841.1 - 1.9e-38 132.0 1.4 2.4e-38 131.6 1.4 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM21841.1 - 4.6e-17 61.7 1.4 9.9e-17 60.7 1.4 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_AsnC-type PF13404.6 AIM21841.1 - 0.021 14.6 0.0 0.046 13.6 0.0 1.6 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Beta-lactamase PF00144.24 AIM21842.1 - 1.9e-64 218.0 4.9 2.3e-64 217.7 4.9 1.0 1 0 0 1 1 1 1 Beta-lactamase MFS_1 PF07690.16 AIM21843.1 - 5.9e-34 117.5 65.7 7.2e-24 84.4 33.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AIM21843.1 - 2.3e-05 23.5 34.3 0.0022 16.9 12.1 3.3 2 1 1 3 3 3 3 Sugar (and other) transporter Abhydrolase_3 PF07859.13 AIM21844.1 - 5.5e-16 59.1 2.0 1.5e-15 57.7 2.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 AIM21844.1 - 7.3e-07 28.4 0.0 5e-06 25.7 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 AIM21844.1 - 4.5e-05 23.0 0.0 0.0001 21.8 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 AIM21844.1 - 0.0017 17.7 0.1 1 8.6 0.0 3.0 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Esterase_phd PF10503.9 AIM21844.1 - 0.0078 15.7 0.2 0.11 12.0 0.2 2.3 1 1 0 1 1 1 1 Esterase PHB depolymerase MAAL_C PF07476.11 AIM21844.1 - 0.061 12.5 0.0 0.093 11.9 0.0 1.2 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus DeoRC PF00455.22 AIM21845.1 - 1.4e-41 142.1 0.0 3.9e-36 124.4 0.0 2.2 1 1 1 2 2 2 2 DeoR C terminal sensor domain HTH_DeoR PF08220.12 AIM21845.1 - 1e-15 57.2 0.2 2.1e-15 56.2 0.2 1.5 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 AIM21845.1 - 2.6e-07 30.5 0.1 5.5e-07 29.4 0.1 1.5 1 0 0 1 1 1 1 HTH domain HTH_5 PF01022.20 AIM21845.1 - 1.7e-05 24.5 0.1 3.7e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family GntR PF00392.21 AIM21845.1 - 3.4e-05 23.4 0.2 7.8e-05 22.3 0.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_AsnC-type PF13404.6 AIM21845.1 - 8.3e-05 22.3 0.7 0.00024 20.8 0.7 1.8 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_IclR PF09339.10 AIM21845.1 - 0.0002 21.1 1.5 0.00052 19.8 1.5 1.7 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR PF01047.22 AIM21845.1 - 0.00041 20.2 0.0 0.00097 19.0 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_Crp_2 PF13545.6 AIM21845.1 - 0.00063 19.7 0.2 0.002 18.1 0.1 1.9 2 0 0 2 2 1 1 Crp-like helix-turn-helix domain HTH_24 PF13412.6 AIM21845.1 - 0.00083 18.9 0.1 0.0022 17.5 0.1 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 AIM21845.1 - 0.001 18.9 1.4 0.0038 17.1 1.4 1.9 1 0 0 1 1 1 1 MarR family TrmB PF01978.19 AIM21845.1 - 0.0017 18.2 0.0 0.0035 17.2 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_36 PF13730.6 AIM21845.1 - 0.0049 16.8 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain DprA_WH PF17782.1 AIM21845.1 - 0.0074 16.4 0.9 0.026 14.6 0.9 2.0 1 0 0 1 1 1 1 DprA winged helix domain HTH_29 PF13551.6 AIM21845.1 - 0.0075 16.3 0.0 0.02 14.9 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn helix DUF742 PF05331.11 AIM21845.1 - 0.013 15.3 0.0 0.031 14.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF742) Crp PF00325.20 AIM21845.1 - 0.016 14.8 0.1 0.05 13.3 0.1 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family HTH_20 PF12840.7 AIM21845.1 - 0.017 15.2 4.9 0.02 15.0 1.3 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain Fe_dep_repress PF01325.19 AIM21845.1 - 0.021 15.0 0.0 0.038 14.2 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain DUF3489 PF11994.8 AIM21845.1 - 0.021 14.9 0.1 0.16 12.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3489) FeoC PF09012.10 AIM21845.1 - 0.025 14.6 0.0 0.05 13.7 0.0 1.4 1 0 0 1 1 1 0 FeoC like transcriptional regulator HTH_15 PF12324.8 AIM21845.1 - 0.035 14.1 0.1 0.087 12.8 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase Rrf2 PF02082.20 AIM21845.1 - 0.039 14.3 0.1 0.1 13.0 0.1 1.7 1 0 0 1 1 1 0 Transcriptional regulator BPL_LplA_LipB_2 PF16917.5 AIM21845.1 - 0.075 12.6 0.3 0.13 11.8 0.3 1.3 1 0 0 1 1 1 0 Biotin/lipoate A/B protein ligase family FaeA PF04703.12 AIM21845.1 - 0.13 12.7 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 FaeA-like protein HTH_28 PF13518.6 AIM21845.1 - 0.16 12.1 1.4 0.24 11.6 0.2 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain DUF4350 PF14258.6 AIM21845.1 - 0.17 12.3 1.0 2.1 8.8 1.0 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4350) RepL PF05732.11 AIM21845.1 - 0.22 10.9 0.0 0.35 10.3 0.0 1.2 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) GFO_IDH_MocA PF01408.22 AIM21846.1 - 2.5e-23 83.1 0.2 4.6e-23 82.3 0.2 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 AIM21846.1 - 1.8e-14 53.7 0.1 2.8e-14 53.1 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 AIM21846.1 - 1.5e-07 32.1 0.4 3.1e-07 31.1 0.4 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 AIM21846.1 - 0.00017 22.0 0.1 0.00036 20.9 0.1 1.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 AIM21846.1 - 0.0007 19.8 0.2 0.0026 18.0 0.2 1.9 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 AIM21846.1 - 0.0023 18.5 0.2 0.0044 17.6 0.2 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent MFS_1 PF07690.16 AIM21847.1 - 7.7e-52 176.4 53.9 7.7e-52 176.4 53.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.13 AIM21847.1 - 9.3e-12 44.1 13.3 9.3e-12 44.1 13.3 2.5 2 1 0 2 2 2 1 Transmembrane secretion effector MFS_1_like PF12832.7 AIM21847.1 - 5.3e-06 25.5 13.0 0.011 14.7 0.0 2.4 2 0 0 2 2 2 2 MFS_1 like family RibD_C PF01872.17 AIM21848.1 - 4.5e-20 72.3 0.0 8.8e-20 71.4 0.0 1.4 1 1 0 1 1 1 1 RibD C-terminal domain DHFR_1 PF00186.19 AIM21848.1 - 0.00047 19.9 0.0 0.00063 19.5 0.0 1.2 1 0 0 1 1 1 1 Dihydrofolate reductase Glyoxalase PF00903.25 AIM21849.1 - 8.2e-08 32.5 0.0 1.3e-07 31.9 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 AIM21849.1 - 5.1e-05 24.0 0.0 7.5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain RHH_1 PF01402.21 AIM21850.1 - 3.8e-05 23.5 0.0 4.5e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family RepB-RCR_reg PF10723.9 AIM21850.1 - 0.0035 17.2 0.1 0.0044 16.9 0.1 1.1 1 0 0 1 1 1 1 Replication regulatory protein RepB RHH_5 PF07878.11 AIM21850.1 - 0.0094 15.8 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 HeH PF12949.7 AIM21850.1 - 0.051 13.3 0.6 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 HeH/LEM domain Methyltransf_25 PF13649.6 AIM21851.1 - 2.3e-05 25.0 0.0 4.3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Spermine_synth PF01564.17 AIM21851.1 - 0.00017 21.1 0.0 0.00022 20.7 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_11 PF08241.12 AIM21851.1 - 0.00099 19.7 0.0 0.0018 18.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 AIM21851.1 - 0.0025 18.8 0.0 0.0049 17.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AIM21851.1 - 0.011 15.3 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.18 AIM21851.1 - 0.017 14.4 0.0 0.028 13.7 0.0 1.3 1 1 0 1 1 1 0 O-methyltransferase domain DUF1887 PF09002.11 AIM21851.1 - 0.073 11.7 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1887) Methyltransf_12 PF08242.12 AIM21851.1 - 0.084 13.6 0.0 0.14 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_PK PF05891.12 AIM21851.1 - 0.13 11.8 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase FabA PF07977.13 AIM21852.1 - 1.4e-20 73.3 0.0 1.7e-20 73.1 0.0 1.0 1 0 0 1 1 1 1 FabA-like domain 4HBT PF03061.22 AIM21852.1 - 0.0011 19.3 0.1 0.0016 18.7 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily AfsA PF03756.13 AIM21852.1 - 0.022 14.8 0.0 0.026 14.5 0.0 1.2 1 0 0 1 1 1 0 A-factor biosynthesis hotdog domain UPF0114 PF03350.16 AIM21853.1 - 7.3e-35 119.7 5.5 7.3e-35 119.7 5.5 1.4 2 0 0 2 2 2 1 Uncharacterized protein family, UPF0114 LysR_substrate PF03466.20 AIM21854.1 - 2.5e-37 128.3 3.3 3.7e-37 127.7 3.3 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM21854.1 - 2e-20 72.5 2.0 2e-20 72.5 2.0 1.6 2 0 0 2 2 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AIM21854.1 - 1.8e-06 27.6 0.8 3.3e-06 26.8 0.8 1.5 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_28 PF13518.6 AIM21854.1 - 0.0084 16.2 1.1 0.021 14.9 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 AIM21854.1 - 0.012 15.0 0.0 0.035 13.5 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_AsnC-type PF13404.6 AIM21854.1 - 0.013 15.3 0.1 0.032 14.1 0.1 1.6 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_20 PF12840.7 AIM21854.1 - 0.015 15.4 0.2 0.035 14.1 0.2 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain DUF2397 PF09660.10 AIM21854.1 - 0.015 14.2 0.6 0.022 13.7 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) HTH_24 PF13412.6 AIM21854.1 - 0.038 13.6 0.1 0.068 12.7 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF2089 PF09862.9 AIM21854.1 - 0.041 13.9 0.0 0.066 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) HTH_50 PF18024.1 AIM21854.1 - 0.047 13.3 0.1 0.13 11.9 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_IclR PF09339.10 AIM21854.1 - 0.049 13.4 3.5 0.082 12.7 1.6 2.4 2 1 0 2 2 2 0 IclR helix-turn-helix domain HTH_31 PF13560.6 AIM21854.1 - 0.065 13.6 1.8 0.41 11.0 0.3 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_23 PF13384.6 AIM21854.1 - 0.066 13.0 0.2 0.26 11.1 0.1 2.1 2 0 0 2 2 2 0 Homeodomain-like domain HTH_8 PF02954.19 AIM21854.1 - 0.078 12.8 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family Rdx PF10262.9 AIM21855.1 - 4.3e-30 103.7 0.0 5.1e-30 103.5 0.0 1.1 1 0 0 1 1 1 1 Rdx family Pyr_redox_2 PF07992.14 AIM21856.1 - 0.016 14.4 0.0 0.035 13.3 0.0 1.3 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_65C PF03633.15 AIM21856.1 - 0.097 12.6 0.0 0.8 9.7 0.0 2.3 2 0 0 2 2 2 0 Glycosyl hydrolase family 65, C-terminal domain Pyr_redox_2 PF07992.14 AIM21857.1 - 7.2e-06 25.4 0.0 7.2e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 AIM21857.1 - 0.0049 16.9 0.2 0.0053 16.8 0.2 1.2 1 1 0 1 1 1 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 AIM21857.1 - 0.0057 15.8 0.1 0.0068 15.5 0.1 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 AIM21857.1 - 0.0074 16.5 0.1 0.0074 16.5 0.1 1.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 AIM21857.1 - 0.0088 15.3 0.1 0.0097 15.2 0.1 1.1 1 0 0 1 1 1 1 Thi4 family K_oxygenase PF13434.6 AIM21857.1 - 0.012 14.8 0.1 0.015 14.5 0.1 1.1 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 AIM21857.1 - 0.014 16.0 0.4 0.024 15.2 0.4 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 AIM21857.1 - 0.018 13.9 0.1 0.022 13.6 0.1 1.1 1 0 0 1 1 1 0 Tryptophan halogenase DAO PF01266.24 AIM21857.1 - 0.023 14.3 3.3 0.028 14.0 3.0 1.3 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 AIM21857.1 - 0.047 12.4 0.0 0.047 12.4 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_7 PF13241.6 AIM21857.1 - 0.12 12.9 0.0 0.13 12.8 0.0 1.2 1 0 0 1 1 1 0 Putative NAD(P)-binding Ribosomal_S22 PF08136.11 AIM21857.1 - 0.15 12.4 0.9 0.27 11.6 0.9 1.4 1 0 0 1 1 1 0 30S ribosomal protein subunit S22 family Pyr_redox_3 PF13738.6 AIM21857.1 - 0.18 11.0 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TauE PF01925.19 AIM21858.1 - 1.8e-39 135.8 31.6 2e-39 135.6 31.6 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE Phage_holin_2_3 PF16080.5 AIM21858.1 - 0.81 9.5 3.9 0.31 10.8 0.4 2.2 2 0 0 2 2 2 0 Bacteriophage holin family HP1 IspA PF04279.15 AIM21858.1 - 9.3 6.4 14.5 2.4 8.3 6.3 2.2 2 0 0 2 2 2 0 Intracellular septation protein A Lactamase_B PF00753.27 AIM21859.1 - 1.6e-20 74.0 1.4 2.8e-20 73.2 1.4 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF442 PF04273.13 AIM21859.1 - 2.4e-05 24.4 0.0 4.5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Putative phosphatase (DUF442) DSPc PF00782.20 AIM21859.1 - 0.22 11.3 0.1 0.44 10.4 0.1 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Unstab_antitox PF09720.10 AIM21859.1 - 0.28 11.2 1.1 15 5.7 0.1 2.8 3 0 0 3 3 3 0 Putative addiction module component ADH_N PF08240.12 AIM21860.1 - 2.4e-27 95.0 10.0 2.4e-27 95.0 10.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AIM21860.1 - 9.5e-26 90.3 1.4 1.6e-25 89.6 1.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AIM21860.1 - 2.7e-10 41.4 0.4 4.2e-10 40.8 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CoA_binding PF02629.19 AIM21860.1 - 0.0012 19.5 2.5 0.0029 18.3 2.5 1.6 1 0 0 1 1 1 1 CoA binding domain Methyltransf_25 PF13649.6 AIM21860.1 - 0.0069 17.1 0.1 0.018 15.7 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain 2-Hacid_dh_C PF02826.19 AIM21860.1 - 0.072 12.4 0.1 0.14 11.5 0.1 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_31 PF13847.6 AIM21860.1 - 0.13 12.0 0.2 0.23 11.3 0.2 1.4 1 0 0 1 1 1 0 Methyltransferase domain Aldedh PF00171.22 AIM21861.1 - 1.1e-160 535.2 0.0 1.2e-160 535.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Sigma54_activat PF00158.26 AIM21862.1 - 3.2e-55 186.4 0.0 5.1e-55 185.7 0.0 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AIM21862.1 - 3.6e-13 49.8 0.0 7.9e-13 48.7 0.0 1.5 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 AIM21862.1 - 1.5e-11 43.9 3.2 2.7e-11 43.1 0.5 2.4 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family GAF PF01590.26 AIM21862.1 - 6.6e-06 26.8 0.5 6.8e-05 23.5 0.1 2.7 3 0 0 3 3 2 1 GAF domain Mg_chelatase PF01078.21 AIM21862.1 - 0.00011 21.6 0.0 0.014 14.8 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI HTH_30 PF13556.6 AIM21862.1 - 0.00019 21.2 0.2 0.00065 19.4 0.2 1.9 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_29 PF13551.6 AIM21862.1 - 0.0021 18.1 0.1 0.0067 16.4 0.1 1.9 1 0 0 1 1 1 1 Winged helix-turn helix HTH_7 PF02796.15 AIM21862.1 - 0.0042 17.1 0.0 0.0099 15.9 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase AAA_5 PF07728.14 AIM21862.1 - 0.0043 17.0 0.0 0.017 15.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) HTH_23 PF13384.6 AIM21862.1 - 0.0071 16.1 3.7 0.0084 15.9 0.1 2.8 3 0 0 3 3 3 1 Homeodomain-like domain AAA PF00004.29 AIM21862.1 - 0.0075 16.7 0.0 0.047 14.1 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) HTH_1 PF00126.27 AIM21862.1 - 0.0083 16.1 0.1 0.028 14.4 0.1 1.9 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_28 PF13518.6 AIM21862.1 - 0.016 15.4 0.2 0.047 13.8 0.2 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain IclR PF01614.18 AIM21862.1 - 0.03 14.1 0.0 0.068 13.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial transcriptional regulator AAA_22 PF13401.6 AIM21862.1 - 0.033 14.5 0.1 1.5 9.1 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_2 PF07724.14 AIM21862.1 - 0.043 13.9 0.0 0.1 12.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) HTH_psq PF05225.16 AIM21862.1 - 0.061 13.1 0.1 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 helix-turn-helix, Psq domain HTH_22 PF13309.6 AIM21862.1 - 0.089 12.9 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 HTH domain HTH_17 PF12728.7 AIM21862.1 - 0.15 12.3 0.1 0.41 10.9 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain AAA_16 PF13191.6 AIM21862.1 - 0.25 11.7 3.3 2.3 8.6 1.4 2.8 2 1 0 2 2 2 0 AAA ATPase domain SBP_bac_3 PF00497.20 AIM21863.1 - 3.7e-37 127.9 0.1 4.4e-37 127.7 0.1 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1 PF09084.11 AIM21863.1 - 0.0044 17.0 0.1 0.026 14.5 0.0 2.0 1 1 1 2 2 2 1 NMT1/THI5 like MFS_1 PF07690.16 AIM21864.1 - 2.7e-47 161.4 61.9 3e-38 131.6 34.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AIM21864.1 - 8.4e-17 61.2 20.5 1.1e-08 34.5 8.2 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 AIM21864.1 - 2e-11 43.4 0.2 0.002 17.1 0.0 2.3 1 1 1 2 2 2 2 MFS_1 like family LacY_symp PF01306.19 AIM21864.1 - 0.04 12.7 7.7 0.37 9.5 3.0 2.7 2 1 0 2 2 2 0 LacY proton/sugar symporter Death_2 PF14786.6 AIM21865.1 - 0.00064 19.7 0.0 0.013 15.4 0.0 2.2 2 0 0 2 2 2 1 Tube Death domain SinI PF08671.10 AIM21865.1 - 0.024 14.4 0.0 0.052 13.3 0.0 1.6 1 0 0 1 1 1 0 Anti-repressor SinI MFS_1 PF07690.16 AIM21866.1 - 3.2e-12 46.1 84.5 2.6e-11 43.0 49.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SinI PF08671.10 AIM21867.1 - 0.097 12.5 1.8 8 6.3 0.0 3.3 4 0 0 4 4 4 0 Anti-repressor SinI YbjN PF10722.9 AIM21867.1 - 0.11 12.5 0.0 5.5 7.1 0.0 2.5 2 0 0 2 2 2 0 Putative bacterial sensory transduction regulator Radical_SAM PF04055.21 AIM21868.1 - 1.1e-15 58.4 0.0 2.1e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily EAL PF00563.20 AIM21869.1 - 5.8e-55 186.4 0.2 1.2e-54 185.4 0.1 1.5 2 0 0 2 2 2 1 EAL domain GGDEF PF00990.21 AIM21869.1 - 3.7e-49 166.6 0.0 5.8e-49 165.9 0.0 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_4 PF08448.10 AIM21869.1 - 7e-19 68.1 0.1 2.8e-15 56.5 0.0 2.8 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 AIM21869.1 - 6e-13 48.9 0.1 1.7e-09 37.8 0.1 3.4 2 1 1 3 3 3 2 PAS fold PAS PF00989.25 AIM21869.1 - 1.8e-07 31.2 0.0 6.1e-05 23.0 0.0 2.8 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 AIM21869.1 - 5.1e-05 23.5 0.0 0.022 15.0 0.0 2.8 2 0 0 2 2 2 2 PAS domain Autotransporter PF03797.19 AIM21870.1 - 6.9e-59 199.5 25.2 1.4e-58 198.5 25.2 1.6 1 0 0 1 1 1 1 Autotransporter beta-domain Peptidase_S8 PF00082.22 AIM21870.1 - 1.1e-37 129.9 2.2 2e-37 129.1 2.2 1.4 1 0 0 1 1 1 1 Subtilase family PATR PF12951.7 AIM21870.1 - 1e-11 44.7 5.9 4.4e-11 42.7 5.9 2.2 1 0 0 1 1 1 1 Passenger-associated-transport-repeat PQQ PF01011.21 AIM21871.1 - 7.4e-44 145.7 0.4 4e-08 32.8 0.1 8.2 8 0 0 8 8 8 7 PQQ enzyme repeat PQQ_2 PF13360.6 AIM21871.1 - 3.8e-19 69.2 0.6 2.2e-06 27.5 0.1 4.6 3 2 0 4 4 4 4 PQQ-like domain DUF2157 PF09925.9 AIM21871.1 - 0.036 13.9 0.4 0.036 13.9 0.4 2.6 1 1 0 2 2 2 0 Predicted membrane protein (DUF2157) PQQ_3 PF13570.6 AIM21871.1 - 0.43 11.1 30.5 0.88 10.1 2.5 9.0 9 3 0 9 9 9 0 PQQ-like domain Radical_SAM PF04055.21 AIM21872.1 - 1.4e-21 77.6 0.0 2.1e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 AIM21872.1 - 1.2e-05 25.6 0.0 2e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AIM21872.1 - 1.7e-05 25.0 0.0 3.1e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain SPASM PF13186.6 AIM21872.1 - 0.00011 22.6 0.0 0.00021 21.7 0.0 1.5 1 0 0 1 1 1 1 Iron-sulfur cluster-binding domain PqqD PF05402.12 AIM21873.1 - 4.1e-13 49.4 0.0 5e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Coenzyme PQQ synthesis protein D (PqqD) TENA_THI-4 PF03070.16 AIM21874.1 - 2.9e-64 216.7 0.1 3.4e-64 216.5 0.1 1.0 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Lactamase_B_2 PF12706.7 AIM21875.1 - 5.3e-36 124.0 0.0 6.3e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain PqqA PF08042.11 AIM21876.1 - 4e-10 39.3 0.0 4.5e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 PqqA family Peptidase_M19 PF01244.21 AIM21877.1 - 1.5e-96 323.4 0.0 1.7e-96 323.2 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Amidohydro_2 PF04909.14 AIM21877.1 - 0.00038 20.3 0.1 0.0037 17.1 0.0 2.5 2 1 0 2 2 2 1 Amidohydrolase Methyltransf_24 PF13578.6 AIM21878.1 - 0.00039 21.4 0.0 0.0005 21.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain DUF2388 PF09498.10 AIM21878.1 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2388) DUF1726 PF08351.11 AIM21878.1 - 0.13 12.2 0.0 0.56 10.2 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1726) TetR_C_18 PF17923.1 AIM21879.1 - 5.9e-52 175.0 1.1 6.9e-52 174.7 1.1 1.1 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_15 PF17918.1 AIM21879.1 - 2.7e-05 24.9 0.6 3.6e-05 24.5 0.6 1.2 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain LysR_substrate PF03466.20 AIM21880.1 - 2.1e-24 86.1 10.5 2.9e-24 85.6 10.5 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM21880.1 - 1.8e-16 59.8 1.4 4.3e-16 58.6 1.4 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 AIM21880.1 - 0.0067 16.3 0.9 0.02 14.8 0.2 2.2 2 0 0 2 2 2 1 MarR family HTH_28 PF13518.6 AIM21880.1 - 0.021 14.9 0.3 0.23 11.6 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_30 PF13556.6 AIM21880.1 - 0.04 13.7 0.5 0.088 12.6 0.5 1.6 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Pyridoxal_deC PF00282.19 AIM21881.1 - 1.1e-63 215.2 0.1 1.4e-63 214.8 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 AIM21881.1 - 1.6e-08 34.2 0.3 3.4e-08 33.1 0.3 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 AIM21881.1 - 0.00039 19.5 0.4 0.0026 16.8 0.1 2.3 3 0 0 3 3 3 1 Aminotransferase class-V SepSecS PF05889.13 AIM21881.1 - 0.0044 15.8 0.0 0.0088 14.8 0.0 1.4 2 0 0 2 2 2 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Aminotran_1_2 PF00155.21 AIM21881.1 - 0.012 14.8 0.2 0.075 12.2 0.0 2.2 2 1 0 2 2 2 0 Aminotransferase class I and II OKR_DC_1 PF01276.20 AIM21881.1 - 0.029 13.1 0.0 0.046 12.5 0.0 1.5 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Aminotran_3 PF00202.21 AIM21882.1 - 1.7e-100 336.5 0.0 2.1e-100 336.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 AIM21882.1 - 0.0018 17.6 0.0 0.01 15.0 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class I and II Oxidored_FMN PF00724.20 AIM21883.1 - 1.3e-47 162.8 0.0 1.5e-47 162.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family His_biosynth PF00977.21 AIM21883.1 - 0.0019 17.7 0.0 0.0035 16.8 0.0 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein Ala_racemase_N PF01168.20 AIM21883.1 - 0.0093 15.6 0.1 0.041 13.5 0.0 2.0 2 0 0 2 2 2 1 Alanine racemase, N-terminal domain MR_MLE_C PF13378.6 AIM21883.1 - 0.0099 15.5 0.1 0.024 14.2 0.1 1.7 1 1 0 1 1 1 1 Enolase C-terminal domain-like ThiG PF05690.14 AIM21883.1 - 0.079 12.3 0.7 0.15 11.3 0.1 1.7 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Dus PF01207.17 AIM21883.1 - 0.08 12.0 0.1 0.71 8.9 0.0 2.2 3 0 0 3 3 3 0 Dihydrouridine synthase (Dus) NanE PF04131.14 AIM21883.1 - 0.11 11.7 0.9 0.2 10.8 0.0 1.8 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase MerR_1 PF13411.6 AIM21884.1 - 1.9e-17 63.1 0.1 3.5e-17 62.2 0.0 1.5 2 0 0 2 2 2 1 MerR HTH family regulatory protein MerR PF00376.23 AIM21884.1 - 1.9e-15 56.3 0.1 3.6e-15 55.4 0.1 1.5 1 0 0 1 1 1 1 MerR family regulatory protein MerR-DNA-bind PF09278.11 AIM21884.1 - 1e-11 45.2 1.3 1.7e-11 44.5 1.3 1.3 1 0 0 1 1 1 1 MerR, DNA binding HTH_31 PF13560.6 AIM21884.1 - 0.047 14.0 0.0 0.14 12.6 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain AbiEi_4 PF13338.6 AIM21884.1 - 0.056 13.6 0.1 0.13 12.4 0.1 1.7 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin HTH_17 PF12728.7 AIM21884.1 - 0.13 12.5 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain DUF4678 PF15727.5 AIM21884.1 - 0.17 11.1 0.0 0.22 10.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4678) GGDEF PF00990.21 AIM21885.1 - 2e-40 138.2 0.0 5.2e-40 136.8 0.0 1.8 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_4 PF08448.10 AIM21885.1 - 3.9e-23 81.8 0.0 4.7e-12 46.1 0.0 3.0 3 0 0 3 3 3 2 PAS fold PAS_3 PF08447.12 AIM21885.1 - 1.3e-15 57.5 0.0 6e-13 48.9 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 AIM21885.1 - 2.9e-14 53.0 0.1 7.9e-07 29.1 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 AIM21885.1 - 2.8e-13 50.0 0.0 2.8e-10 40.4 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS_8 PF13188.7 AIM21885.1 - 7.1e-09 35.5 0.3 0.0033 17.4 0.0 2.7 2 0 0 2 2 2 2 PAS domain GAF PF01590.26 AIM21885.1 - 9.5e-08 32.7 0.0 3.4e-07 30.9 0.0 2.0 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 AIM21885.1 - 5e-05 23.6 0.0 0.0001 22.6 0.0 1.5 1 0 0 1 1 1 1 GAF domain PAS_7 PF12860.7 AIM21885.1 - 5.6e-05 23.3 0.1 0.07 13.3 0.0 3.3 2 2 0 2 2 2 2 PAS fold Cauli_AT PF03233.13 AIM21885.1 - 0.042 13.8 0.2 0.083 12.8 0.2 1.5 1 0 0 1 1 1 0 Aphid transmission protein PAS_11 PF14598.6 AIM21885.1 - 0.1 12.7 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 PAS domain SKA2 PF16740.5 AIM21885.1 - 1.1 9.0 5.2 8.5 6.2 1.8 3.3 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 LysR_substrate PF03466.20 AIM21886.1 - 5.2e-27 94.6 3.6 5.2e-27 94.6 3.6 1.5 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AIM21886.1 - 2.1e-20 72.4 1.8 1.5e-19 69.7 1.2 2.4 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 AIM21886.1 - 0.062 13.2 0.1 0.23 11.4 0.1 2.0 2 0 0 2 2 2 0 MarR family HTH_24 PF13412.6 AIM21886.1 - 0.068 12.7 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MFS_1 PF07690.16 AIM21887.1 - 3.6e-23 82.1 68.5 4.1e-18 65.4 33.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DAO PF01266.24 AIM21888.1 - 3.2e-36 125.6 6.7 4e-36 125.3 6.7 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AIM21888.1 - 1.4e-06 27.7 4.2 9.8e-05 21.6 1.5 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 AIM21888.1 - 0.00054 20.1 0.2 0.0024 18.1 0.2 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 AIM21888.1 - 0.0075 15.6 0.1 1.4 8.2 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 AIM21888.1 - 0.023 13.9 0.2 4.1 6.5 0.2 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AIM21888.1 - 0.025 13.3 0.3 0.28 9.8 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein 3HCDH_N PF02737.18 AIM21888.1 - 0.058 13.3 0.5 0.092 12.6 0.5 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 AIM21888.1 - 0.072 12.7 1.1 0.12 12.1 0.3 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.7 AIM21888.1 - 0.24 10.7 1.9 1 8.6 1.8 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 AIM21888.1 - 0.66 9.0 1.7 20 4.1 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A APH PF01636.23 AIM21889.1 - 0.038 13.9 0.1 0.04 13.8 0.1 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Cupin_7 PF12973.7 AIM21891.1 - 4.4e-06 26.5 0.0 4.9e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 ChrR Cupin-like domain Cupin_2 PF07883.11 AIM21891.1 - 0.00087 19.0 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 Cupin domain DUF4437 PF14499.6 AIM21891.1 - 0.14 11.2 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4437) HTH_18 PF12833.7 AIM21892.1 - 2.4e-18 66.2 0.2 5.3e-18 65.1 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AIM21892.1 - 8e-10 38.6 0.9 0.00084 19.4 0.2 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family AraC_binding PF02311.19 AIM21892.1 - 3.8e-07 30.1 0.3 1e-06 28.7 0.2 1.7 1 1 0 1 1 1 1 AraC-like ligand binding domain Cupin_2 PF07883.11 AIM21892.1 - 0.002 17.8 0.1 0.0045 16.7 0.1 1.5 1 0 0 1 1 1 1 Cupin domain PLDc_2 PF13091.6 AIM21893.1 - 8.3e-40 135.8 0.0 1.9e-19 69.8 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 AIM21893.1 - 1.4e-11 44.0 0.2 3.3e-05 23.9 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PP_kinase_C PF13090.6 AIM21893.1 - 0.0043 16.5 0.0 0.61 9.5 0.0 2.3 2 0 0 2 2 2 2 Polyphosphate kinase C-terminal domain 2 FAM83 PF07894.12 AIM21893.1 - 0.045 13.3 0.0 1 8.8 0.0 2.2 2 0 0 2 2 2 0 FAM83 A-H Thioredoxin PF00085.20 AIM21894.1 - 1.6e-13 50.5 0.0 1.8e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 AIM21894.1 - 5.1e-06 26.9 0.0 1.8e-05 25.1 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 AIM21894.1 - 0.0024 17.7 0.0 0.003 17.4 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein OST3_OST6 PF04756.13 AIM21894.1 - 0.0046 16.3 0.0 0.0053 16.1 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 AIM21894.1 - 0.006 16.9 0.0 0.012 16.0 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.6 AIM21894.1 - 0.036 14.2 0.0 0.047 13.9 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin-like AhpC-TSA PF00578.21 AIM21894.1 - 0.091 12.7 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family Glutaredoxin PF00462.24 AIM21894.1 - 0.13 12.5 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin MAPEG PF01124.18 AIM21895.1 - 1.3e-17 63.9 5.8 1.4e-17 63.8 5.8 1.0 1 0 0 1 1 1 1 MAPEG family HTH_5 PF01022.20 AIM21896.1 - 1.4e-11 44.1 1.3 2e-11 43.6 1.3 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 AIM21896.1 - 1.5e-08 34.6 1.0 3.3e-08 33.5 0.9 1.6 1 1 1 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.7 AIM21896.1 - 1.7e-06 27.8 0.3 3.5e-06 26.8 0.3 1.6 1 1 0 1 1 1 1 MarR family HTH_24 PF13412.6 AIM21896.1 - 6.4e-06 25.6 0.0 1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_34 PF13601.6 AIM21896.1 - 6.2e-05 23.1 0.1 8.5e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain TFIIE_alpha PF02002.17 AIM21896.1 - 8.8e-05 22.3 0.1 0.0002 21.2 0.1 1.6 1 1 0 1 1 1 1 TFIIE alpha subunit MarR PF01047.22 AIM21896.1 - 0.00015 21.6 0.1 0.001 19.0 0.1 1.9 2 0 0 2 2 2 1 MarR family Rrf2 PF02082.20 AIM21896.1 - 0.0012 19.1 0.3 0.0039 17.5 0.2 1.7 2 0 0 2 2 2 1 Transcriptional regulator TrmB PF01978.19 AIM21896.1 - 0.0052 16.6 0.0 0.0074 16.1 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HxlR PF01638.17 AIM21896.1 - 0.023 14.5 0.1 0.026 14.4 0.1 1.2 1 0 0 1 1 1 0 HxlR-like helix-turn-helix BLACT_WH PF17778.1 AIM21896.1 - 0.026 14.5 0.0 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase associated winged helix domain HTH_Crp_2 PF13545.6 AIM21896.1 - 0.032 14.2 0.2 0.064 13.2 0.2 1.6 1 1 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_1 PF00126.27 AIM21896.1 - 0.033 14.1 0.1 0.21 11.5 0.1 2.1 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_IclR PF09339.10 AIM21896.1 - 0.075 12.8 1.2 0.19 11.6 1.2 1.7 1 1 0 1 1 1 0 IclR helix-turn-helix domain ADH_zinc_N PF00107.26 AIM21897.1 - 6.8e-26 90.8 0.0 9.4e-26 90.3 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AIM21897.1 - 6.3e-22 77.5 0.0 1.8e-20 72.9 0.0 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 AIM21897.1 - 8.2e-13 49.6 0.0 1.6e-12 48.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 AIM21897.1 - 0.00044 19.8 0.1 0.0037 16.8 0.1 2.0 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus AP_endonuc_2 PF01261.24 AIM21898.1 - 1.6e-32 112.7 0.0 2.1e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel AP_endonuc_2_N PF07582.12 AIM21898.1 - 5.4e-10 38.8 0.1 8.5e-10 38.2 0.1 1.3 1 0 0 1 1 1 1 AP endonuclease family 2 C terminus GFO_IDH_MocA PF01408.22 AIM21899.1 - 8.4e-29 100.8 0.0 1.4e-28 100.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 AIM21899.1 - 7.4e-20 71.1 0.0 1.4e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Peripla_BP_4 PF13407.6 AIM21900.1 - 6.5e-54 183.2 13.1 8.2e-54 182.9 13.1 1.0 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 AIM21900.1 - 3.8e-13 49.5 2.8 4.7e-13 49.2 2.8 1.2 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_3 PF13377.6 AIM21900.1 - 8.9e-08 32.6 0.1 1.4e-07 32.0 0.1 1.3 1 0 0 1 1 1 1 Periplasmic binding protein-like domain PucR PF07905.11 AIM21900.1 - 0.001 19.3 0.1 0.0064 16.8 0.1 2.2 2 0 0 2 2 2 1 Purine catabolism regulatory protein-like family Peripla_BP_1 PF00532.21 AIM21901.1 - 1.1e-21 77.5 0.2 1.4e-21 77.1 0.2 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_3 PF13377.6 AIM21901.1 - 2.5e-18 67.0 2.5 4.3e-18 66.2 0.2 2.3 2 1 1 3 3 3 1 Periplasmic binding protein-like domain Peripla_BP_4 PF13407.6 AIM21901.1 - 1.5e-14 54.2 0.0 2.6e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein domain LacI PF00356.21 AIM21901.1 - 2.3e-13 49.7 0.1 4.7e-13 48.7 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family HTH_Tnp_ISL3 PF13542.6 AIM21901.1 - 0.0049 16.2 0.3 0.018 14.4 0.1 2.2 2 1 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 TetR_N PF00440.23 AIM21901.1 - 0.021 14.6 0.1 0.083 12.7 0.1 2.0 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family HTH_3 PF01381.22 AIM21901.1 - 0.14 12.2 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix B12-binding PF02310.19 AIM21901.1 - 0.22 11.6 0.8 12 6.0 0.1 2.4 1 1 1 2 2 2 0 B12 binding domain HTH_10 PF04967.12 AIM21901.1 - 0.23 11.3 0.8 1.5 8.7 0.0 2.6 3 0 0 3 3 3 0 HTH DNA binding domain DUF4440 PF14534.6 AIM21902.1 - 0.004 17.5 0.0 0.0043 17.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Mcl1_mid PF12341.8 AIM21902.1 - 0.066 12.6 0.0 0.067 12.5 0.0 1.0 1 0 0 1 1 1 0 Minichromosome loss protein, Mcl1, middle region Glyoxalase PF00903.25 AIM21905.1 - 3.6e-06 27.2 0.0 4.3e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily tRNA_edit PF04073.15 AIM21906.1 - 2.2e-26 92.3 0.0 2.7e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain Tn916-Xis PF09035.10 AIM21906.1 - 0.017 15.3 0.0 0.026 14.7 0.0 1.2 1 0 0 1 1 1 0 Excisionase from transposon Tn916 Ub-Mut7C PF14451.6 AIM21906.1 - 0.049 13.5 0.1 0.098 12.5 0.1 1.5 1 0 0 1 1 1 0 Mut7-C ubiquitin DUF2231 PF09990.9 AIM21907.1 - 5.7e-05 23.5 8.3 9e-05 22.9 8.3 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2231) DUF1011 PF06237.12 AIM21907.1 - 0.057 13.8 1.9 0.057 13.8 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1011) DUF4231 PF14015.6 AIM21907.1 - 2.3 8.7 10.4 0.15 12.5 4.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) GSDH PF07995.11 AIM21908.1 - 4.4e-16 59.1 0.0 4.7e-14 52.4 0.0 2.8 2 1 0 2 2 2 1 Glucose / Sorbosone dehydrogenase NHL PF01436.21 AIM21908.1 - 0.0012 18.8 1.4 0.11 12.6 0.3 3.4 3 0 0 3 3 3 1 NHL repeat SGL PF08450.12 AIM21908.1 - 0.054 13.1 0.1 10 5.6 0.0 3.1 3 1 0 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region DUF2946 PF11162.8 AIM21909.1 - 7.1e-14 52.5 16.8 1.1e-13 51.8 16.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2946) TonB_dep_Rec PF00593.24 AIM21910.1 - 1.1e-44 154.2 17.4 1.4e-44 153.8 17.4 1.1 1 0 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AIM21910.1 - 5.4e-12 46.2 0.7 3.3e-11 43.7 0.0 2.5 3 0 0 3 3 3 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 AIM21910.1 - 0.03 13.3 0.8 0.15 11.0 0.8 2.0 1 1 0 1 1 1 0 Outer membrane protein beta-barrel family OMP_b-brl PF13505.6 AIM21910.1 - 2.2 8.3 21.8 0.013 15.7 3.1 3.7 1 1 1 3 3 3 0 Outer membrane protein beta-barrel domain LysR_substrate PF03466.20 AIM21911.1 - 8.4e-24 84.1 2.5 8.4e-24 84.1 2.5 1.7 2 1 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AIM21911.1 - 1.7e-15 56.7 0.1 4.3e-15 55.4 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_5 PF01022.20 AIM21911.1 - 0.0027 17.5 0.1 0.0063 16.4 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_30 PF13556.6 AIM21911.1 - 0.0051 16.6 0.0 0.015 15.1 0.0 1.8 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain HTH_28 PF13518.6 AIM21911.1 - 0.011 15.9 0.0 0.094 12.9 0.0 2.6 2 1 1 3 3 3 0 Helix-turn-helix domain DUF1127 PF06568.11 AIM21911.1 - 0.26 11.0 0.2 0.26 11.0 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1127) Flavodoxin_2 PF02525.17 AIM21912.1 - 1.6e-56 191.2 0.0 1.9e-56 190.9 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 AIM21912.1 - 1.2e-13 51.1 0.0 1.9e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase LysE PF01810.18 AIM21913.1 - 1.5e-27 96.3 11.6 1.7e-27 96.2 11.6 1.0 1 0 0 1 1 1 1 LysE type translocator Mntp PF02659.15 AIM21913.1 - 0.0001 22.1 6.4 0.00015 21.5 0.4 2.1 2 0 0 2 2 2 2 Putative manganese efflux pump TerC PF03741.16 AIM21913.1 - 0.00028 20.6 1.2 0.00048 19.9 1.2 1.4 1 1 0 1 1 1 1 Integral membrane protein TerC family CAAD PF14159.6 AIM21913.1 - 0.058 13.2 0.4 0.13 12.2 0.4 1.6 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Flavodoxin_2 PF02525.17 AIM21914.1 - 1.1e-39 136.3 0.4 1.2e-39 136.0 0.4 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 AIM21914.1 - 1.4e-06 28.1 0.0 1.9e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase DUF4965 PF16335.5 AIM21914.1 - 0.02 14.5 0.5 2.6 7.6 0.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4965) HxlR PF01638.17 AIM21915.1 - 2e-29 101.3 0.1 2.4e-29 101.0 0.1 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix DUF4364 PF14277.6 AIM21915.1 - 0.0027 17.5 0.0 0.0035 17.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) PadR PF03551.14 AIM21915.1 - 0.0091 15.9 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family MFS_3 PF05977.13 AIM21916.1 - 6.2e-29 100.8 34.0 7.8e-29 100.5 34.0 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1 PF07690.16 AIM21916.1 - 4.1e-28 98.3 51.1 4.1e-28 98.3 51.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 AIM21916.1 - 0.00089 18.2 28.6 0.022 13.6 9.1 3.6 2 2 1 3 3 3 2 Sugar (and other) transporter CcmD PF04995.14 AIM21916.1 - 0.12 12.5 0.3 0.12 12.5 0.3 3.7 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) MbtH PF03621.13 AIM21917.1 - 1.7e-25 88.2 0.1 2.2e-25 87.9 0.1 1.1 1 0 0 1 1 1 1 MbtH-like protein Esterase PF00756.20 AIM21918.1 - 4e-36 124.9 0.1 6.5e-36 124.2 0.1 1.3 1 0 0 1 1 1 1 Putative esterase DUF3327 PF11806.8 AIM21918.1 - 5.3e-35 120.8 4.5 5.3e-35 120.8 4.5 2.6 1 1 1 2 2 2 1 Domain of unknown function (DUF3327) Peptidase_S9 PF00326.21 AIM21918.1 - 0.0015 18.1 0.0 0.0025 17.3 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 AIM21918.1 - 0.025 14.4 0.0 0.05 13.4 0.0 1.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 AIM21918.1 - 0.026 13.8 0.0 0.079 12.2 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 TonB_dep_Rec PF00593.24 AIM21919.1 - 1.1e-63 216.8 26.8 1.7e-63 216.1 26.8 1.3 1 0 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AIM21919.1 - 1.3e-19 70.7 0.2 3.4e-19 69.4 0.2 1.8 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain PAS_6 PF08348.11 AIM21920.1 - 5.8e-22 77.7 0.0 9.4e-22 77.0 0.0 1.4 1 0 0 1 1 1 1 YheO-like PAS domain HTH_22 PF13309.6 AIM21920.1 - 6.2e-17 61.4 0.0 1e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 HTH domain HTH_Crp_2 PF13545.6 AIM21920.1 - 0.097 12.7 0.1 0.76 9.8 0.1 2.2 1 1 0 1 1 1 0 Crp-like helix-turn-helix domain ABM PF03992.16 AIM21921.1 - 0.052 13.7 0.0 0.061 13.4 0.0 1.2 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase ELFV_dehydrog PF00208.21 AIM21922.1 - 4.9e-74 249.1 0.6 6.1e-74 248.8 0.6 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 AIM21922.1 - 8.1e-55 184.2 0.0 1.3e-54 183.5 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 2-Hacid_dh_C PF02826.19 AIM21922.1 - 9.1e-05 21.9 0.3 0.00016 21.1 0.3 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.21 AIM21922.1 - 0.0034 16.8 0.4 0.006 16.0 0.4 1.3 1 0 0 1 1 1 1 ThiF family AlaDh_PNT_C PF01262.21 AIM21922.1 - 0.016 14.5 2.8 0.03 13.6 2.8 1.5 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.21 AIM21922.1 - 0.02 14.9 0.1 0.049 13.7 0.1 1.7 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_7 PF13241.6 AIM21922.1 - 0.038 14.4 0.3 0.066 13.7 0.3 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.27 AIM21922.1 - 0.071 13.7 0.2 0.23 12.0 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 AIM21922.1 - 0.14 12.0 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AMP-binding PF00501.28 AIM21923.1 - 1.4e-110 369.8 0.0 1.6e-110 369.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AIM21923.1 - 2.6e-21 76.4 1.2 3.6e-20 72.7 0.8 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DJ-1_PfpI PF01965.24 AIM21924.1 - 3.3e-49 166.9 0.0 3.7e-49 166.7 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 AIM21924.1 - 0.0032 17.3 0.0 0.0039 17.0 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I ThiJ_like PF17124.5 AIM21924.1 - 0.014 15.1 0.1 0.043 13.5 0.1 2.0 1 1 0 1 1 1 0 ThiJ/PfpI family-like Peptidase_C26 PF07722.13 AIM21924.1 - 0.035 13.9 0.1 0.065 13.0 0.1 1.5 1 1 0 1 1 1 0 Peptidase C26 DUF1493 PF07377.12 AIM21925.1 - 5.6e-20 71.8 0.0 6.4e-20 71.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1493) FAM110_C PF14160.6 AIM21925.1 - 0.27 12.3 0.6 3.9 8.6 0.6 2.0 1 1 0 1 1 1 0 Centrosome-associated C terminus OEP PF02321.18 AIM21926.1 - 4.9e-51 173.2 35.7 1.3e-28 100.1 13.8 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein ACR_tran PF00873.19 AIM21927.1 - 0 1223.5 17.5 0 1223.3 17.5 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AIM21927.1 - 1.4e-07 30.7 11.4 1.4e-07 30.7 11.4 2.7 3 0 0 3 3 3 2 MMPL family SecD_SecF PF02355.16 AIM21927.1 - 6e-07 29.0 25.7 0.002 17.6 11.2 2.4 2 0 0 2 2 2 2 Protein export membrane protein Patched PF02460.18 AIM21927.1 - 0.03 12.4 9.1 0.062 11.4 9.1 1.5 1 0 0 1 1 1 0 Patched family DUF4232 PF14016.6 AIM21927.1 - 0.036 14.2 0.1 0.12 12.5 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4232) HlyD_D23 PF16576.5 AIM21928.1 - 2e-15 56.6 3.3 4e-15 55.6 3.3 1.5 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 AIM21928.1 - 1.8e-14 53.3 1.8 6.6e-12 45.1 0.3 3.4 3 0 0 3 3 3 2 Biotin-lipoyl like HlyD_3 PF13437.6 AIM21928.1 - 2.6e-09 37.8 4.6 9.8e-06 26.2 0.2 3.1 2 0 0 2 2 2 2 HlyD family secretion protein HlyD PF00529.20 AIM21928.1 - 0.0021 17.9 17.3 0.0052 16.6 17.3 2.0 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS DUF3324 PF11797.8 AIM21928.1 - 0.058 13.4 0.1 0.28 11.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function C-terminal (DUF3324) Biotin_lipoyl PF00364.22 AIM21928.1 - 0.06 13.2 0.0 1.1 9.2 0.0 2.6 2 0 0 2 2 2 0 Biotin-requiring enzyme Methyltransf_23 PF13489.6 AIM21929.1 - 8.2e-14 51.8 0.0 1.2e-13 51.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AIM21929.1 - 9.4e-14 51.5 0.0 1.5e-13 50.8 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AIM21929.1 - 1.2e-12 48.3 0.0 2e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AIM21929.1 - 4.4e-10 40.1 0.0 9.5e-10 39.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIM21929.1 - 4e-09 37.1 0.0 6.5e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 AIM21929.1 - 7.8e-05 22.3 0.0 0.00012 21.8 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW NodS PF05401.11 AIM21929.1 - 0.00069 19.3 0.0 0.00085 19.0 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.18 AIM21929.1 - 0.0027 17.1 0.0 0.0039 16.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 AIM21929.1 - 0.004 16.6 0.0 0.066 12.7 0.0 2.3 2 1 0 2 2 2 1 Putative methyltransferase Pox_MCEL PF03291.16 AIM21929.1 - 0.012 14.8 0.0 0.015 14.4 0.0 1.1 1 0 0 1 1 1 0 mRNA capping enzyme PAD_porph PF04371.15 AIM21930.1 - 1.1e-96 323.9 0.0 1.2e-96 323.7 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase Cadherin_5 PF17892.1 AIM21930.1 - 0.02 14.8 0.1 0.04 13.9 0.1 1.4 1 0 0 1 1 1 0 Cadherin-like domain Amidinotransf PF02274.17 AIM21930.1 - 0.15 11.1 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 Amidinotransferase LysR_substrate PF03466.20 AIM21931.1 - 8.1e-27 93.9 2.4 1.5e-26 93.1 2.4 1.4 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM21931.1 - 3.3e-21 75.0 2.4 5.8e-21 74.2 2.4 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 AIM21931.1 - 0.0073 16.2 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 MarR family HTH_5 PF01022.20 AIM21931.1 - 0.046 13.6 0.1 0.087 12.7 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family G_glu_transpept PF01019.21 AIM21932.1 - 2.9e-169 564.1 0.1 3.3e-169 563.9 0.1 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Molybdopterin PF00384.22 AIM21933.1 - 9.2e-26 90.8 0.0 1.4e-25 90.1 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 AIM21933.1 - 1.5e-14 54.0 0.0 2.5e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain DeoRC PF00455.22 AIM21934.1 - 4.2e-45 153.6 1.1 5.8e-45 153.1 1.1 1.2 1 0 0 1 1 1 1 DeoR C terminal sensor domain HTH_DeoR PF08220.12 AIM21934.1 - 4.1e-18 64.9 0.2 7.9e-18 64.0 0.2 1.4 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 AIM21934.1 - 8.5e-08 32.0 0.2 1.5e-07 31.3 0.2 1.4 1 0 0 1 1 1 1 HTH domain HTH_5 PF01022.20 AIM21934.1 - 4.1e-05 23.4 0.0 7.3e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_AsnC-type PF13404.6 AIM21934.1 - 0.00014 21.6 0.0 0.00029 20.6 0.0 1.6 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 AIM21934.1 - 0.00015 21.2 0.3 0.00026 20.5 0.3 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding GntR PF00392.21 AIM21934.1 - 0.00015 21.3 0.0 0.00035 20.2 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_20 PF12840.7 AIM21934.1 - 0.0019 18.2 0.0 0.004 17.2 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain TFIIE_alpha PF02002.17 AIM21934.1 - 0.0026 17.6 0.1 0.0057 16.5 0.1 1.5 1 0 0 1 1 1 1 TFIIE alpha subunit MarR_2 PF12802.7 AIM21934.1 - 0.0034 17.2 0.0 0.0076 16.1 0.0 1.5 1 0 0 1 1 1 1 MarR family MarR PF01047.22 AIM21934.1 - 0.0037 17.2 0.0 0.0082 16.0 0.0 1.5 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.20 AIM21934.1 - 0.01 16.1 0.0 0.023 15.0 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator HTH_Crp_2 PF13545.6 AIM21934.1 - 0.014 15.4 0.2 0.1 12.6 0.0 2.1 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain FeoC PF09012.10 AIM21934.1 - 0.014 15.5 0.0 0.041 14.0 0.0 1.8 1 1 1 2 2 2 0 FeoC like transcriptional regulator Put_DNA-bind_N PF06971.13 AIM21934.1 - 0.029 14.4 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus DUF2250 PF10007.9 AIM21934.1 - 0.044 13.9 0.0 0.091 12.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) E3_UFM1_ligase PF09743.9 AIM21934.1 - 0.058 13.0 0.1 0.088 12.4 0.1 1.2 1 0 0 1 1 1 0 E3 UFM1-protein ligase 1 TrmB PF01978.19 AIM21934.1 - 0.063 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_36 PF13730.6 AIM21934.1 - 0.073 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain DUF480 PF04337.12 AIM21934.1 - 0.12 12.5 0.1 0.21 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF480 HTH_Mga PF08280.11 AIM21934.1 - 0.16 12.0 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain Pyr_redox_2 PF07992.14 AIM21935.1 - 2.1e-19 69.9 0.0 2.9e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AIM21935.1 - 2.7e-15 56.4 0.0 4.5e-08 32.7 0.5 2.7 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AIM21935.1 - 2.5e-09 37.2 0.4 5.8e-07 29.7 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AIM21935.1 - 7.2e-09 35.7 6.2 0.00014 21.6 1.6 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 AIM21935.1 - 1.2e-07 31.3 0.2 2.8e-07 30.1 0.2 1.6 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 AIM21935.1 - 1.3e-06 27.4 1.7 0.0016 17.2 1.2 2.7 3 0 0 3 3 3 2 HI0933-like protein Amino_oxidase PF01593.24 AIM21935.1 - 3.8e-06 26.5 3.3 0.017 14.4 0.7 3.1 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 AIM21935.1 - 7.5e-06 26.4 0.1 0.11 13.1 0.2 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AIM21935.1 - 1.7e-05 24.4 4.8 0.00099 18.6 3.5 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AIM21935.1 - 1.9e-05 23.9 5.7 5.4e-05 22.5 1.2 2.7 2 1 1 3 3 3 1 FAD binding domain NAD_binding_9 PF13454.6 AIM21935.1 - 0.00015 21.8 2.4 0.19 11.7 0.4 3.0 2 1 1 3 3 3 2 FAD-NAD(P)-binding Thi4 PF01946.17 AIM21935.1 - 0.0011 18.3 0.2 0.002 17.4 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Shikimate_DH PF01488.20 AIM21935.1 - 0.0073 16.4 0.1 0.018 15.1 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 AIM21935.1 - 0.03 13.4 5.6 0.04 13.0 2.4 2.1 1 1 1 2 2 2 0 Glucose inhibited division protein A IlvN PF07991.12 AIM21935.1 - 0.041 13.4 0.1 0.092 12.3 0.1 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 AIM21935.1 - 0.13 12.6 0.1 0.39 11.0 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain K_oxygenase PF13434.6 AIM21935.1 - 0.17 11.0 0.0 11 5.0 0.0 2.5 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 AIM21935.1 - 0.25 10.2 1.0 0.36 9.6 1.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Lycopene_cycl PF05834.12 AIM21935.1 - 0.3 10.1 4.5 1.9 7.4 1.6 2.6 1 1 2 3 3 3 0 Lycopene cyclase protein DAO PF01266.24 AIM21936.1 - 3.2e-50 171.7 0.9 4.8e-50 171.1 0.9 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Fer2_BFD PF04324.15 AIM21936.1 - 2e-07 31.2 1.0 4.4e-07 30.2 1.0 1.6 1 0 0 1 1 1 1 BFD-like [2Fe-2S] binding domain Pyr_redox_2 PF07992.14 AIM21936.1 - 0.013 14.7 0.1 0.053 12.7 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AIM21936.1 - 0.11 13.1 0.3 0.25 11.9 0.3 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FGGY_N PF00370.21 AIM21937.1 - 1.9e-52 178.3 0.0 2.8e-52 177.7 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 AIM21937.1 - 1.9e-32 112.6 0.0 4.2e-32 111.5 0.0 1.5 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 AIM21937.1 - 0.00038 20.1 0.0 0.013 15.0 0.1 2.1 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family EutH PF04346.12 AIM21938.1 - 2.4e-105 352.6 33.0 2.7e-105 352.4 33.0 1.0 1 0 0 1 1 1 1 Ethanolamine utilisation protein, EutH DUF1937 PF09152.10 AIM21939.1 - 6.1e-42 143.1 0.1 6.8e-42 142.9 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1937) DUF3857 PF12969.7 AIM21940.1 - 3e-31 108.7 0.6 6.8e-31 107.6 0.6 1.6 1 0 0 1 1 1 1 Domain of Unknown Function with PDB structure (DUF3857) Transglut_core PF01841.19 AIM21940.1 - 4.5e-09 36.7 0.0 1.5e-08 35.0 0.0 1.9 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF3858 PF12970.7 AIM21940.1 - 2.1e-05 24.5 0.0 5.1e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Domain of Unknown Function with PDB structure (DUF3858) HTH_3 PF01381.22 AIM21941.1 - 1.1e-16 60.6 0.2 1.7e-16 60.0 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 AIM21941.1 - 9.7e-12 45.1 1.8 1.9e-11 44.1 1.8 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 AIM21941.1 - 9.6e-09 35.1 0.0 1.4e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Cupin_2 PF07883.11 AIM21941.1 - 2.3e-06 27.2 0.0 4.7e-06 26.2 0.0 1.5 2 0 0 2 2 2 1 Cupin domain HTH_26 PF13443.6 AIM21941.1 - 7.3e-06 26.3 0.0 1.5e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_37 PF13744.6 AIM21941.1 - 5e-05 23.2 0.0 8.3e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 AIM21941.1 - 0.0001 22.1 0.5 0.00022 21.0 0.5 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Phage_CI_repr PF07022.13 AIM21941.1 - 0.0016 18.5 0.0 0.0023 18.0 0.0 1.2 1 0 0 1 1 1 1 Bacteriophage CI repressor helix-turn-helix domain HTH_IclR PF09339.10 AIM21941.1 - 0.0028 17.4 0.2 0.0087 15.8 0.2 1.8 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 AIM21941.1 - 0.0055 16.6 0.1 0.015 15.2 0.1 1.7 1 0 0 1 1 1 1 MarR family CENP-B_N PF04218.13 AIM21941.1 - 0.016 14.8 0.1 0.028 14.0 0.1 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain Cupin_6 PF12852.7 AIM21941.1 - 0.017 14.8 0.0 0.029 14.1 0.0 1.6 1 1 0 1 1 1 0 Cupin Cupin_3 PF05899.12 AIM21941.1 - 0.021 14.5 0.0 0.083 12.6 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF861) HTH_10 PF04967.12 AIM21941.1 - 0.068 13.0 0.1 0.19 11.6 0.1 1.7 1 0 0 1 1 1 0 HTH DNA binding domain TetR_N PF00440.23 AIM21941.1 - 0.081 12.7 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family HTH_35 PF13693.6 AIM21941.1 - 0.12 12.4 0.2 0.22 11.6 0.2 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding EamA PF00892.20 AIM21942.1 - 4.8e-25 88.3 41.6 5e-13 49.4 17.0 2.1 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.6 AIM21942.1 - 0.0029 17.2 9.8 0.0029 17.2 9.8 1.9 1 1 1 2 2 2 1 Putative multidrug resistance efflux transporter rve PF00665.26 AIM21943.1 - 1.2e-26 93.2 0.1 2.1e-26 92.5 0.1 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 AIM21943.1 - 2.8e-20 71.9 0.0 5.8e-20 70.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 AIM21943.1 - 0.00086 19.6 0.0 0.0017 18.6 0.0 1.5 1 0 0 1 1 1 1 DDE domain HTH_21 PF13276.6 AIM21943.1 - 0.0028 17.8 1.6 0.0061 16.7 0.7 2.0 2 0 0 2 2 2 1 HTH-like domain rve_2 PF13333.6 AIM21943.1 - 0.0055 16.9 0.0 0.01 16.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DUF4802 PF16060.5 AIM21943.1 - 0.079 13.1 0.9 0.16 12.2 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4802) Sugarporin_N PF11471.8 AIM21944.1 - 0.015 15.3 0.4 0.023 14.6 0.4 1.2 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension TRAF_BIRC3_bd PF16673.5 AIM21944.1 - 0.036 13.8 0.1 0.062 13.1 0.1 1.4 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain PKcGMP_CC PF16808.5 AIM21944.1 - 0.053 13.4 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Pox_A_type_inc PF04508.12 AIM21944.1 - 0.18 11.7 0.4 0.41 10.6 0.4 1.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Nitroreductase PF00881.24 AIM21945.1 - 7.2e-31 107.5 0.4 8.6e-31 107.3 0.4 1.1 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 AIM21945.1 - 2e-06 27.5 0.1 0.0026 17.3 0.0 2.5 1 1 1 2 2 2 2 Putative TM nitroreductase Cytochrom_C PF00034.21 AIM21946.1 - 1.7e-21 77.2 0.0 4.5e-07 30.9 0.0 3.4 3 0 0 3 3 3 3 Cytochrome c Cytochrome_CBB3 PF13442.6 AIM21946.1 - 3e-21 75.5 0.2 1.3e-08 35.0 0.0 3.5 3 0 0 3 3 3 3 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 AIM21946.1 - 3.9e-08 33.1 0.0 0.0056 16.4 0.0 3.6 3 0 0 3 3 3 2 Cytochrome c-550 domain Cytochrome_C7 PF14522.6 AIM21946.1 - 0.00013 21.8 0.2 2.3 8.3 0.0 3.2 3 0 0 3 3 3 1 Cytochrome c7 and related cytochrome c Paired_CXXCH_1 PF09699.10 AIM21946.1 - 0.00064 19.4 3.3 7.3 6.4 0.0 3.3 3 0 0 3 3 3 3 Doubled CXXCH motif (Paired_CXXCH_1) Haem_bd PF14376.6 AIM21946.1 - 0.24 11.3 2.1 3.1 7.7 0.0 2.9 4 0 0 4 4 4 0 Haem-binding domain DUF3716 PF12511.8 AIM21946.1 - 0.33 11.0 3.1 1.7 8.8 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3716) GSu_C4xC__C2xCH PF09698.10 AIM21946.1 - 4.8 8.0 11.0 1.9 9.4 0.2 3.8 4 0 0 4 4 4 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) Ald_Xan_dh_C2 PF02738.18 AIM21947.1 - 9.4e-70 235.6 0.3 1.9e-28 99.3 0.0 3.2 2 1 1 3 3 3 3 Molybdopterin-binding domain of aldehyde dehydrogenase TAT_signal PF10518.9 AIM21947.1 - 0.012 15.4 0.0 0.057 13.3 0.0 2.3 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Ald_Xan_dh_C PF01315.22 AIM21947.1 - 0.019 15.3 0.0 0.5 10.8 0.0 2.5 1 1 1 2 2 2 0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain DUF1824 PF08854.10 AIM21947.1 - 0.17 11.8 0.0 1.6 8.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1824) Fer2_2 PF01799.20 AIM21948.1 - 1.5e-25 89.0 0.3 1.5e-25 89.0 0.3 1.5 2 0 0 2 2 2 1 [2Fe-2S] binding domain Fer2_3 PF13085.6 AIM21948.1 - 5.5e-05 23.1 2.3 0.00025 21.0 2.3 2.0 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.27 AIM21948.1 - 0.00013 21.9 0.1 0.00013 21.9 0.1 2.2 2 1 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 AIM21948.1 - 0.091 12.8 0.1 0.21 11.7 0.1 1.5 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain TetR_C_1 PF02909.17 AIM21949.1 - 9.1e-27 93.7 0.0 1.8e-26 92.7 0.0 1.5 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 AIM21949.1 - 1.1e-14 53.9 0.0 4.1e-14 52.1 0.0 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_Tnp_1_2 PF13022.6 AIM21949.1 - 0.12 12.5 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase HTH_psq PF05225.16 AIM21949.1 - 0.18 11.6 0.0 0.78 9.5 0.0 1.9 2 0 0 2 2 2 0 helix-turn-helix, Psq domain MFS_1 PF07690.16 AIM21950.1 - 2e-48 165.2 46.7 1.5e-37 129.3 27.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AIM21950.1 - 2.1e-11 43.3 15.6 3.3e-11 42.7 3.1 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 AIM21950.1 - 1.4e-09 37.3 11.8 1e-07 31.2 6.1 2.8 1 1 2 3 3 3 3 MFS_1 like family MFS_4 PF06779.14 AIM21950.1 - 3e-06 26.8 30.2 4.2e-06 26.3 30.2 1.3 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB LacY_symp PF01306.19 AIM21950.1 - 0.00037 19.4 3.7 0.0008 18.3 1.5 2.0 2 0 0 2 2 2 1 LacY proton/sugar symporter Nuc_H_symport PF03825.16 AIM21950.1 - 0.0093 15.0 6.4 0.022 13.8 3.4 2.4 1 1 1 2 2 2 2 Nucleoside H+ symporter Acetyltransf_18 PF18014.1 AIM21950.1 - 0.19 11.6 0.3 0.5 10.2 0.1 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain NMT1_2 PF13379.6 AIM21951.1 - 9.2e-17 61.6 0.1 1.6e-16 60.8 0.1 1.4 1 1 0 1 1 1 1 NMT1-like family NMT1 PF09084.11 AIM21951.1 - 1e-15 58.3 0.0 1.4e-15 57.9 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like OpuAC PF04069.12 AIM21951.1 - 2.2e-13 50.4 0.3 4.3e-13 49.4 0.3 1.5 1 1 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system Phosphonate-bd PF12974.7 AIM21951.1 - 7.3e-09 35.6 0.1 1.5e-08 34.5 0.1 1.5 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 AIM21951.1 - 3.4e-08 33.2 0.0 6.3e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1_3 PF16868.5 AIM21951.1 - 4.8e-07 29.5 0.0 7.1e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 NMT1-like family HEM4 PF02602.15 AIM21951.1 - 0.047 13.0 0.0 0.11 11.9 0.0 1.6 2 0 0 2 2 2 0 Uroporphyrinogen-III synthase HemD HTH_6 PF01418.17 AIM21952.1 - 4.7e-16 58.5 0.0 1.1e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain, rpiR family SIS PF01380.22 AIM21952.1 - 1.1e-15 57.6 0.1 1.8e-15 56.9 0.1 1.3 1 0 0 1 1 1 1 SIS domain LacI PF00356.21 AIM21952.1 - 0.0009 19.0 0.0 0.002 17.9 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family HTH_24 PF13412.6 AIM21952.1 - 0.0014 18.2 0.0 0.0033 17.0 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding RepL PF05732.11 AIM21952.1 - 0.0023 17.4 0.0 0.0039 16.6 0.0 1.3 1 0 0 1 1 1 1 Firmicute plasmid replication protein (RepL) IF2_N PF04760.15 AIM21952.1 - 0.0094 15.8 0.0 0.026 14.4 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region HTH_17 PF12728.7 AIM21952.1 - 0.012 15.7 0.0 0.029 14.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_AsnC-type PF13404.6 AIM21952.1 - 0.016 15.0 0.0 0.042 13.7 0.0 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_IclR PF09339.10 AIM21952.1 - 0.016 15.0 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_Crp_2 PF13545.6 AIM21952.1 - 0.043 13.8 0.0 0.17 11.9 0.0 2.0 1 1 1 2 2 2 0 Crp-like helix-turn-helix domain HTH_50 PF18024.1 AIM21952.1 - 0.043 13.4 0.0 0.15 11.7 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_38 PF13936.6 AIM21952.1 - 0.045 13.5 0.2 0.38 10.6 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_11 PF08279.12 AIM21952.1 - 0.059 13.3 0.0 0.21 11.6 0.0 1.9 2 0 0 2 2 2 0 HTH domain RWP-RK PF02042.15 AIM21952.1 - 0.09 12.8 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 RWP-RK domain HTH_3 PF01381.22 AIM21952.1 - 0.12 12.5 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix TetR_N PF00440.23 AIM21952.1 - 0.12 12.1 0.1 0.32 10.8 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family HTH_Tnp_ISL3 PF13542.6 AIM21952.1 - 0.17 11.3 0.0 0.52 9.8 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 MarR PF01047.22 AIM21952.1 - 0.17 11.8 0.0 0.5 10.3 0.0 1.8 2 0 0 2 2 2 0 MarR family Glyco_hydro_1 PF00232.18 AIM21953.1 - 3.9e-132 440.9 1.9 4.5e-132 440.7 1.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Cellulase PF00150.18 AIM21953.1 - 0.0032 17.0 0.0 0.0051 16.3 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) FAD_binding_3 PF01494.19 AIM21954.1 - 6.1e-83 278.9 0.0 7.1e-83 278.7 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 AIM21954.1 - 0.00027 21.1 0.0 0.00089 19.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 AIM21954.1 - 0.0014 17.4 0.0 0.0023 16.7 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 AIM21954.1 - 0.0093 15.2 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 AIM21954.1 - 0.011 14.6 0.7 5.2 5.8 0.0 3.0 3 0 0 3 3 3 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 AIM21954.1 - 0.022 14.0 0.2 0.065 12.5 0.2 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AIM21954.1 - 0.022 13.8 1.8 0.034 13.2 0.2 1.8 1 1 1 2 2 2 0 FAD binding domain DAO PF01266.24 AIM21954.1 - 0.068 12.7 3.2 0.095 12.3 2.8 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 AIM21954.1 - 0.083 11.9 0.2 0.19 10.7 0.1 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 AIM21954.1 - 0.091 12.0 0.1 0.22 10.7 0.1 1.6 1 1 1 2 2 2 0 Thi4 family ApbA PF02558.16 AIM21954.1 - 0.094 12.4 0.1 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 AIM21954.1 - 0.2 11.7 0.1 0.32 11.0 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MFS_1 PF07690.16 AIM21955.1 - 2.1e-50 171.6 73.8 4.2e-34 118.0 31.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AIM21955.1 - 3.1e-24 85.7 35.4 4.6e-24 85.1 9.5 2.1 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 AIM21955.1 - 5.6e-08 32.5 36.8 6.5e-08 32.3 10.6 2.1 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 AIM21955.1 - 7.1e-05 21.8 30.8 0.00038 19.4 9.2 2.2 2 0 0 2 2 2 2 MFS_1 like family MFS_2 PF13347.6 AIM21955.1 - 0.00035 19.2 33.1 0.0058 15.2 12.0 2.8 2 2 0 2 2 2 2 MFS/sugar transport protein UPF0227 PF05728.12 AIM21955.1 - 0.025 14.5 0.5 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) DUF1512 PF07431.12 AIM21955.1 - 0.27 10.2 0.1 0.5 9.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) PALP PF00291.25 AIM21956.1 - 2.3e-60 204.5 0.1 3.4e-60 203.9 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NmrA PF05368.13 AIM21956.1 - 0.055 13.0 0.0 0.083 12.4 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family VIT1 PF01988.19 AIM21957.1 - 1e-52 179.2 14.0 1.1e-52 179.0 14.0 1.0 1 0 0 1 1 1 1 VIT family 3-dmu-9_3-mt PF06983.13 AIM21958.1 - 3.6e-36 124.2 0.0 4.4e-36 123.9 0.0 1.1 1 0 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase DUF1428 PF07237.11 AIM21959.1 - 2e-47 159.6 0.3 2.2e-47 159.4 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1428) NIPSNAP PF07978.13 AIM21959.1 - 0.068 13.4 0.1 0.21 11.8 0.1 1.8 1 1 0 1 1 1 0 NIPSNAP GGDEF PF00990.21 AIM21960.1 - 7.1e-38 129.9 0.0 1.4e-37 129.0 0.0 1.5 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain MASE1 PF05231.14 AIM21960.1 - 3.2e-05 23.2 43.0 4.5e-05 22.8 43.0 1.2 1 0 0 1 1 1 1 MASE1 TonB_dep_Rec PF00593.24 AIM21961.1 - 9.2e-57 194.0 37.2 9.2e-57 194.0 37.2 1.5 1 1 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AIM21961.1 - 2.4e-16 60.2 4.1 4.4e-16 59.4 3.1 2.0 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain Abhydrolase_1 PF00561.20 AIM21962.1 - 1.1e-21 77.6 1.4 1.4e-16 60.9 1.7 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AIM21962.1 - 1.3e-17 65.2 15.7 3.6e-17 63.7 15.7 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AIM21962.1 - 5.4e-17 61.9 2.0 5.8e-14 51.9 1.0 2.1 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Thioesterase PF00975.20 AIM21962.1 - 0.00034 20.8 0.4 0.00041 20.5 0.4 1.3 1 1 0 1 1 1 1 Thioesterase domain FSH1 PF03959.13 AIM21962.1 - 0.00068 19.3 0.0 0.0013 18.4 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 AIM21962.1 - 0.0022 17.9 0.1 0.13 12.1 0.0 2.7 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase AXE1 PF05448.12 AIM21962.1 - 0.15 10.7 0.9 0.79 8.3 0.0 2.1 3 0 0 3 3 3 0 Acetyl xylan esterase (AXE1) Ser_hydrolase PF06821.13 AIM21962.1 - 0.16 11.8 0.1 0.46 10.3 0.1 1.8 1 1 0 1 1 1 0 Serine hydrolase LPAM_1 PF08139.12 AIM21963.1 - 0.15 12.6 4.3 0.54 10.9 4.3 1.8 1 1 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site MS_channel PF00924.18 AIM21964.1 - 9.3e-43 146.2 1.9 9.3e-43 146.2 1.9 2.9 2 0 0 2 2 2 1 Mechanosensitive ion channel DUF3772 PF12607.8 AIM21964.1 - 9.4e-19 66.9 0.4 2.8e-18 65.4 0.4 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3772) Mit_proteolip PF08039.11 AIM21964.1 - 0.079 13.4 0.1 0.3 11.6 0.1 2.0 1 0 0 1 1 1 0 Mitochondrial proteolipid Plasmid_RAQPRD PF09686.10 AIM21964.1 - 1.8 8.8 6.3 3.4 8.0 0.8 2.5 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) DUF5339 PF17274.2 AIM21964.1 - 2.3 9.2 10.1 3.2 8.7 3.0 2.7 2 1 1 3 3 3 0 Family of unknown function (DUF5339) Cytochrom_B562 PF07361.11 AIM21964.1 - 7.1 7.3 8.2 0.99 10.1 3.2 2.0 2 0 0 2 2 2 0 Cytochrome b562 ABC_tran PF00005.27 AIM21965.1 - 6.2e-47 159.5 0.0 1.3e-24 87.2 0.0 3.2 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 AIM21965.1 - 3.4e-18 66.5 12.0 0.00083 19.2 0.3 4.2 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIM21965.1 - 5.3e-11 42.4 0.1 0.098 12.1 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AIM21965.1 - 1.6e-08 34.9 0.2 0.00083 19.6 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_15 PF13175.6 AIM21965.1 - 2e-07 31.1 0.1 0.018 14.7 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 AIM21965.1 - 2.5e-07 30.7 0.1 0.019 14.8 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase NACHT PF05729.12 AIM21965.1 - 2.5e-06 27.5 0.3 0.066 13.1 0.0 2.8 2 1 0 2 2 2 2 NACHT domain MMR_HSR1 PF01926.23 AIM21965.1 - 2.8e-06 27.4 0.0 0.031 14.4 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 AIM21965.1 - 2.9e-06 26.9 3.0 0.11 12.3 0.4 3.4 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_23 PF13476.6 AIM21965.1 - 6.1e-06 26.9 6.1 0.22 12.0 0.0 3.6 4 0 0 4 4 3 2 AAA domain AAA_16 PF13191.6 AIM21965.1 - 2.3e-05 24.9 13.3 0.0028 18.1 0.1 3.9 1 1 2 4 4 4 2 AAA ATPase domain ATP-synt_ab PF00006.25 AIM21965.1 - 0.0001 22.1 0.0 0.076 12.7 0.0 2.3 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_28 PF13521.6 AIM21965.1 - 0.00012 22.4 0.7 0.56 10.4 0.0 3.0 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 AIM21965.1 - 0.00025 21.4 0.0 1 9.8 0.0 2.4 2 0 0 2 2 2 2 RNA helicase AAA_5 PF07728.14 AIM21965.1 - 0.00037 20.5 0.0 0.26 11.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ABC_tran_Xtn PF12848.7 AIM21965.1 - 0.00068 19.6 3.9 0.0014 18.6 3.9 1.4 1 0 0 1 1 1 1 ABC transporter DUF815 PF05673.13 AIM21965.1 - 0.0008 18.6 0.0 0.073 12.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Roc PF08477.13 AIM21965.1 - 0.00091 19.4 0.0 2.8 8.2 0.0 2.9 3 0 0 3 3 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 AIM21965.1 - 0.0014 18.8 0.3 2.2 8.4 0.0 3.5 4 0 0 4 4 3 1 AAA domain Rad17 PF03215.15 AIM21965.1 - 0.0015 18.5 0.0 0.69 9.8 0.1 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_18 PF13238.6 AIM21965.1 - 0.0026 18.3 0.0 2.2 8.9 0.1 2.9 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 AIM21965.1 - 0.0028 17.2 0.0 1.9 7.9 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region Zeta_toxin PF06414.12 AIM21965.1 - 0.0029 16.9 1.4 3.4 6.9 0.0 3.1 3 0 0 3 3 3 1 Zeta toxin PduV-EutP PF10662.9 AIM21965.1 - 0.0038 17.0 0.1 0.66 9.7 0.1 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.22 AIM21965.1 - 0.0039 16.4 0.0 1.7 7.8 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain Dynamin_N PF00350.23 AIM21965.1 - 0.0071 16.4 0.1 3.6 7.6 0.0 2.8 3 0 0 3 3 3 1 Dynamin family Ras PF00071.22 AIM21965.1 - 0.0077 15.8 0.0 3.2 7.3 0.0 2.6 3 0 0 3 3 2 1 Ras family AAA PF00004.29 AIM21965.1 - 0.0087 16.5 0.0 6 7.3 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PRK PF00485.18 AIM21965.1 - 0.0088 15.8 0.0 4.2 7.1 0.0 2.8 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family MeaB PF03308.16 AIM21965.1 - 0.01 14.8 0.0 0.55 9.2 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF2813 PF11398.8 AIM21965.1 - 0.011 15.0 0.8 2.1 7.5 0.0 2.5 3 0 0 3 3 2 0 Protein of unknown function (DUF2813) KAP_NTPase PF07693.14 AIM21965.1 - 0.025 13.8 0.0 2.2 7.4 0.0 2.4 2 1 0 2 2 2 0 KAP family P-loop domain AAA_14 PF13173.6 AIM21965.1 - 0.026 14.6 0.0 3.2 7.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 AIM21965.1 - 0.03 14.6 0.9 4.3 7.6 0.1 3.6 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit SRPRB PF09439.10 AIM21965.1 - 0.039 13.4 0.1 5.9 6.3 0.0 2.8 3 0 0 3 3 2 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 AIM21965.1 - 0.041 13.6 0.0 11 5.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 AIM21965.1 - 0.052 13.1 1.9 9.7 5.7 0.0 3.3 3 1 0 3 3 3 0 AAA domain FeoB_N PF02421.18 AIM21965.1 - 0.06 12.9 0.0 13 5.3 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_30 PF13604.6 AIM21965.1 - 0.071 12.8 0.0 3.1 7.5 0.0 2.7 2 2 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 AIM21965.1 - 0.087 12.5 0.0 16 5.2 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 AIM21965.1 - 0.092 12.6 0.0 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 AIM21965.1 - 0.15 11.4 0.4 10 5.4 0.0 2.9 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI MCM PF00493.23 AIM21965.1 - 0.21 10.7 0.0 4.7 6.2 0.0 2.2 2 0 0 2 2 2 0 MCM P-loop domain dNK PF01712.19 AIM21965.1 - 0.21 11.4 0.0 15 5.4 0.0 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase DUF4337 PF14235.6 AIM21965.1 - 0.27 11.4 3.3 0.68 10.0 3.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF87 PF01935.17 AIM21965.1 - 0.35 10.9 0.9 4 7.5 0.0 2.5 3 0 0 3 3 2 0 Helicase HerA, central domain Inositol_P PF00459.25 AIM21967.1 - 3.2e-47 161.3 0.0 3.8e-47 161.1 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Cation_efflux PF01545.21 AIM21968.1 - 8.2e-44 149.7 13.2 1.2e-43 149.2 13.2 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 AIM21968.1 - 1.3e-37 127.7 5.2 1.4e-14 54.0 0.4 3.2 3 0 0 3 3 3 3 Dimerisation domain of Zinc Transporter Pilus_CpaD PF09476.10 AIM21968.1 - 0.047 13.4 0.3 0.1 12.3 0.3 1.6 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) DUF4140 PF13600.6 AIM21968.1 - 0.073 13.5 2.0 0.3 11.5 0.0 2.7 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DinI PF06183.13 AIM21968.1 - 0.15 12.4 0.3 1.1 9.7 0.1 2.5 3 0 0 3 3 3 0 DinI-like family Insulin_TMD PF17870.1 AIM21968.1 - 2 8.5 5.4 0.29 11.2 0.5 2.1 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment MgtE PF01769.16 AIM21971.1 - 2e-27 96.0 11.5 3.3e-27 95.3 11.5 1.4 1 0 0 1 1 1 1 Divalent cation transporter CBS PF00571.28 AIM21971.1 - 1.4e-08 35.0 0.3 0.0054 17.2 0.1 2.4 2 0 0 2 2 2 2 CBS domain SBP_bac_5 PF00496.22 AIM21972.1 - 6.4e-81 272.2 6.8 9.3e-81 271.7 6.8 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle SBP_bac_6 PF13343.6 AIM21975.1 - 6.4e-26 91.2 2.0 1e-25 90.6 2.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AIM21975.1 - 2e-21 77.3 8.2 8e-21 75.3 8.2 1.8 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 AIM21975.1 - 6.1e-20 72.2 4.1 7.8e-20 71.8 4.1 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 AIM21975.1 - 6.2e-20 71.9 1.0 8.5e-20 71.5 1.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein BPD_transp_1 PF00528.22 AIM21976.1 - 1.7e-26 93.1 49.5 4.2e-21 75.5 13.9 3.8 2 2 1 3 3 3 3 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 AIM21977.1 - 1.8e-16 60.9 0.0 3.1e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter TOBE_2 PF08402.10 AIM21977.1 - 0.0005 20.2 0.4 0.0021 18.2 0.0 2.3 3 0 0 3 3 3 1 TOBE domain SMC_N PF02463.19 AIM21977.1 - 0.0038 16.7 0.0 0.0053 16.2 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 AIM21977.1 - 0.0097 16.1 0.3 0.045 14.0 0.3 2.0 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 AIM21977.1 - 0.03 14.1 0.0 0.04 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Isochorismatase PF00857.20 AIM21978.1 - 9.1e-31 107.4 0.0 1e-30 107.2 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family Abhydrolase_1 PF00561.20 AIM21979.1 - 2.8e-34 118.9 0.0 4e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 AIM21979.1 - 1.4e-20 73.3 0.0 4.1e-20 71.8 0.0 1.8 1 0 0 1 1 1 1 TAP-like protein Ser_hydrolase PF06821.13 AIM21979.1 - 0.0041 17.0 0.0 0.14 12.0 0.0 2.3 2 0 0 2 2 2 1 Serine hydrolase Hydrolase_4 PF12146.8 AIM21979.1 - 0.02 14.2 0.1 2.2 7.5 0.0 2.8 3 0 0 3 3 3 0 Serine aminopeptidase, S33 DUF883 PF05957.13 AIM21980.1 - 2.7e-11 43.9 2.2 3.7e-11 43.5 2.2 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) CsbD PF05532.12 AIM21980.1 - 1.5e-09 37.6 1.5 1.9e-09 37.3 1.5 1.2 1 0 0 1 1 1 1 CsbD-like ProQ PF04352.13 AIM21980.1 - 0.023 14.6 0.1 0.027 14.4 0.1 1.2 1 0 0 1 1 1 0 ProQ/FINO family GTP_EFTU PF00009.27 AIM21981.1 - 1.3e-64 217.3 0.0 1.9e-64 216.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 AIM21981.1 - 1.5e-45 153.9 0.1 3e-45 152.9 0.1 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 AIM21981.1 - 1.8e-34 117.7 0.2 5.2e-34 116.2 0.0 2.0 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_C PF00679.24 AIM21981.1 - 1.1e-31 108.7 0.1 2.6e-31 107.5 0.1 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 AIM21981.1 - 1.1e-16 61.0 0.1 2.5e-16 59.8 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 AIM21981.1 - 3.2e-05 23.7 0.0 6.6e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 AIM21981.1 - 0.0097 16.0 0.0 0.02 15.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 AIM21981.1 - 0.097 12.6 0.0 0.3 11.0 0.0 1.8 1 0 0 1 1 1 0 Elongation factor Tu domain 4 EamA PF00892.20 AIM21982.1 - 1.8e-21 76.8 21.8 3.6e-16 59.6 2.1 2.8 1 1 0 2 2 2 2 EamA-like transporter family 7TMR-DISM_7TM PF07695.11 AIM21982.1 - 0.053 13.4 17.4 0.02 14.8 2.3 2.7 2 1 0 2 2 2 0 7TM diverse intracellular signalling HlyIII PF03006.20 AIM21982.1 - 1.8 8.2 5.2 0.71 9.5 1.0 2.3 2 1 0 2 2 2 0 Haemolysin-III related Bax1-I PF01027.20 AIM21982.1 - 3.7 7.3 14.4 5.1 6.9 2.5 2.5 1 1 1 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 AraC_binding PF02311.19 AIM21983.1 - 1.4e-25 89.8 0.5 1.4e-25 89.8 0.5 1.5 2 0 0 2 2 2 1 AraC-like ligand binding domain HTH_18 PF12833.7 AIM21983.1 - 6.4e-18 64.8 1.1 6.4e-18 64.8 1.1 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 AIM21983.1 - 3.3e-14 52.6 0.1 1.4e-06 28.2 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family DUF2802 PF10975.8 AIM21983.1 - 0.084 13.0 0.1 0.51 10.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) HTH_7 PF02796.15 AIM21983.1 - 0.17 11.9 0.0 3.3 7.8 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase Aldedh PF00171.22 AIM21984.1 - 1.8e-156 521.3 0.5 2.1e-156 521.1 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Abhydrolase_3 PF07859.13 AIM21985.1 - 3.8e-71 239.3 0.3 5.8e-71 238.7 0.3 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 AIM21985.1 - 5.6e-08 32.1 0.0 1.7e-07 30.5 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 AIM21985.1 - 0.01 15.3 0.0 0.026 14.0 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family AXE1 PF05448.12 AIM21985.1 - 0.11 11.1 0.1 0.16 10.6 0.1 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF2974 PF11187.8 AIM21985.1 - 0.28 10.7 0.0 0.37 10.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.20 AIM21986.1 - 1.5e-18 67.4 0.3 2.6e-18 66.6 0.3 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AIM21986.1 - 3.5e-14 53.9 7.9 4.2e-14 53.7 7.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AIM21986.1 - 0.0024 17.2 0.0 0.0036 16.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 EHN PF06441.12 AIM21986.1 - 0.14 12.5 0.1 0.36 11.2 0.0 1.7 2 0 0 2 2 2 0 Epoxide hydrolase N terminus AP_endonuc_2 PF01261.24 AIM21987.1 - 2.7e-34 118.5 0.0 3.8e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel AP_endonuc_2_N PF07582.12 AIM21987.1 - 1.3e-20 72.9 0.0 2.3e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 AP endonuclease family 2 C terminus TetR_N PF00440.23 AIM21988.1 - 1.1e-14 53.9 0.2 3.2e-14 52.4 0.2 1.9 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 AIM21988.1 - 5.2e-06 26.7 2.8 5.2e-06 26.7 2.8 1.6 1 1 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_13 PF16925.5 AIM21988.1 - 7.3e-05 22.7 0.0 0.00014 21.8 0.0 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_6 PF13977.6 AIM21988.1 - 0.0032 17.7 5.3 0.0078 16.4 5.2 1.8 1 1 1 2 2 2 1 BetI-type transcriptional repressor, C-terminal TPR_10 PF13374.6 AIM21988.1 - 0.95 9.4 4.5 1.2 9.1 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Cupin_2 PF07883.11 AIM21989.1 - 1.1e-10 41.1 0.0 1.3e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 AIM21989.1 - 0.035 14.0 0.0 0.048 13.6 0.0 1.1 1 0 0 1 1 1 0 AraC-like ligand binding domain Rop-like PF05082.13 AIM21989.1 - 0.16 11.8 0.0 0.56 10.1 0.0 1.8 2 0 0 2 2 2 0 Rop-like Glucosamine_iso PF01182.20 AIM21990.1 - 1.2e-15 58.0 0.0 3.9e-15 56.4 0.0 1.8 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K_trans PF02705.16 AIM21991.1 - 5.9e-199 662.0 22.0 6.7e-199 661.8 22.0 1.0 1 0 0 1 1 1 1 K+ potassium transporter LysR_substrate PF03466.20 AIM21992.1 - 1.4e-29 103.0 0.1 2.5e-29 102.1 0.0 1.4 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AIM21992.1 - 8.8e-17 60.8 1.1 1.8e-16 59.8 1.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_5 PF01022.20 AIM21992.1 - 0.0051 16.6 0.1 0.01 15.6 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family P22_Cro PF14549.6 AIM21992.1 - 0.011 15.6 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro HTH_30 PF13556.6 AIM21992.1 - 0.048 13.5 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain BPD_transp_2 PF02653.16 AIM21993.1 - 2.1e-50 171.4 39.6 2.5e-50 171.1 39.6 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component TetR_C_34 PF17929.1 AIM21993.1 - 0.034 14.2 3.2 1.1 9.4 0.6 2.5 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain COX14 PF14880.6 AIM21993.1 - 0.24 11.3 5.4 1.2 9.0 2.5 3.1 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Cytochrom_B_C PF00032.17 AIM21993.1 - 4.6 7.6 6.6 0.43 10.9 0.9 2.3 3 0 0 3 3 3 0 Cytochrome b(C-terminal)/b6/petD BPD_transp_2 PF02653.16 AIM21994.1 - 1.1e-50 172.3 27.8 1.1e-50 172.3 27.8 1.3 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component DUF3169 PF11368.8 AIM21994.1 - 2.6 7.5 4.3 3.8 6.9 2.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) ABC_tran PF00005.27 AIM21995.1 - 1.5e-29 103.3 0.0 2e-29 102.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter BCA_ABC_TP_C PF12399.8 AIM21995.1 - 2.7e-08 33.5 0.9 5.1e-08 32.7 0.9 1.4 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_21 PF13304.6 AIM21995.1 - 0.00033 20.6 0.3 0.0049 16.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AIM21995.1 - 0.0088 16.6 0.0 0.013 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AIM21995.1 - 0.032 14.0 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 AIM21995.1 - 0.043 13.5 0.1 0.064 13.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AIM21995.1 - 0.049 13.9 0.6 0.46 10.8 0.6 2.2 1 1 0 1 1 1 0 AAA domain AAA_13 PF13166.6 AIM21995.1 - 0.28 9.8 0.0 0.37 9.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AIM21996.1 - 9.9e-27 94.1 0.0 1.3e-26 93.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIM21996.1 - 4.2e-11 43.2 0.8 8.4e-05 22.5 0.2 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 AIM21996.1 - 0.0016 18.2 0.0 0.0052 16.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AIM21996.1 - 0.016 15.5 0.1 0.082 13.2 0.1 1.9 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.19 AIM21996.1 - 0.017 14.6 0.2 2.3 7.6 0.1 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_27 PF13514.6 AIM21996.1 - 0.043 13.4 0.0 0.075 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AIM21996.1 - 0.057 13.9 0.1 0.084 13.4 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 AIM21996.1 - 0.093 13.1 0.5 0.33 11.3 0.5 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_15 PF13175.6 AIM21996.1 - 0.1 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 AIM21996.1 - 0.16 11.8 0.2 0.37 10.6 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 AIM21996.1 - 0.21 11.8 0.8 0.36 11.1 0.4 1.8 2 1 0 2 2 2 0 AAA domain Peripla_BP_6 PF13458.6 AIM21997.1 - 7.6e-64 216.5 11.0 8.7e-64 216.3 11.0 1.0 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 AIM21997.1 - 7.4e-21 74.6 0.0 9.6e-21 74.3 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_5 PF13433.6 AIM21997.1 - 9.1e-13 47.9 0.0 1.6e-06 27.4 0.0 2.2 2 0 0 2 2 2 2 Periplasmic binding protein domain ATC_hydrolase PF14196.6 AIM21998.1 - 2.9e-38 131.9 0.1 3.3e-38 131.7 0.1 1.0 1 0 0 1 1 1 1 L-2-amino-thiazoline-4-carboxylic acid hydrolase Peptidase_M20 PF01546.28 AIM21999.1 - 1.7e-34 119.3 0.3 2.2e-34 119.0 0.3 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AIM21999.1 - 0.00028 20.8 0.0 0.00062 19.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 AIM21999.1 - 0.005 16.5 0.0 0.0087 15.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Fer2_4 PF13510.6 AIM21999.1 - 0.055 13.5 0.1 0.34 11.0 0.0 2.3 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain HTH_20 PF12840.7 AIM22000.1 - 6e-15 55.0 0.3 6e-15 55.0 0.3 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_5 PF01022.20 AIM22000.1 - 4.5e-10 39.2 0.0 7.3e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 AIM22000.1 - 5.7e-07 29.3 0.2 9.4e-07 28.6 0.2 1.3 1 0 0 1 1 1 1 MarR family MarR PF01047.22 AIM22000.1 - 0.00093 19.1 0.0 0.0032 17.4 0.0 1.8 2 0 0 2 2 2 1 MarR family HTH_IclR PF09339.10 AIM22000.1 - 0.0072 16.1 0.2 0.013 15.3 0.2 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_27 PF13463.6 AIM22000.1 - 0.013 15.9 0.0 0.021 15.3 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_47 PF16221.5 AIM22000.1 - 0.11 12.1 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 winged helix-turn-helix DprA_WH PF17782.1 AIM22000.1 - 0.14 12.3 2.0 0.15 12.2 0.2 1.9 2 0 0 2 2 2 0 DprA winged helix domain AHSA1 PF08327.11 AIM22001.1 - 5.6e-18 65.4 0.1 1.9e-17 63.6 0.1 1.7 1 1 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein CorA PF01544.18 AIM22002.1 - 1.8e-53 181.8 1.8 2.2e-53 181.5 1.8 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein SH3_6 PF12913.7 AIM22005.1 - 2.1e-22 78.4 0.2 4.4e-22 77.4 0.2 1.6 1 0 0 1 1 1 1 SH3 domain (SH3b1 type) N_NLPC_P60 PF12912.7 AIM22005.1 - 6.8e-16 58.7 0.1 1.2e-15 57.9 0.1 1.4 1 0 0 1 1 1 1 NLPC_P60 stabilising domain, N term SH3_7 PF12914.7 AIM22005.1 - 5.4e-09 36.1 0.0 1.2e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 SH3 domain of SH3b2 type NUDIX PF00293.28 AIM22006.1 - 3.2e-20 72.5 0.0 3.7e-20 72.3 0.0 1.0 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 AIM22006.1 - 0.00065 19.7 0.0 0.0016 18.4 0.0 1.6 1 1 0 1 1 1 1 NUDIX domain Peptidase_S11 PF00768.20 AIM22007.1 - 4.5e-58 196.5 0.0 5.7e-58 196.2 0.0 1.0 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Beta-lactamase2 PF13354.6 AIM22007.1 - 9.1e-09 35.2 0.1 1.2e-08 34.8 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase enzyme family Peptidase_S13 PF02113.15 AIM22007.1 - 8e-05 21.5 0.1 0.0018 17.1 0.1 2.1 1 1 0 2 2 2 1 D-Ala-D-Ala carboxypeptidase 3 (S13) family Beta-lactamase PF00144.24 AIM22007.1 - 0.077 12.2 0.2 0.48 9.6 0.0 1.9 2 0 0 2 2 2 0 Beta-lactamase Bac_luciferase PF00296.20 AIM22008.1 - 5e-29 101.7 11.6 1.1e-28 100.6 11.6 1.5 1 1 0 1 1 1 1 Luciferase-like monooxygenase Peripla_BP_6 PF13458.6 AIM22008.1 - 0.00024 20.9 1.1 0.00038 20.2 1.1 1.4 1 0 0 1 1 1 1 Periplasmic binding protein ALP_N PF17989.1 AIM22008.1 - 0.08 13.1 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Actin like proteins N terminal domain Aminotran_1_2 PF00155.21 AIM22009.1 - 6.7e-20 71.6 0.0 8.5e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II GntR PF00392.21 AIM22009.1 - 1.4e-16 59.9 0.8 1.4e-16 59.9 0.8 2.1 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family Rrf2 PF02082.20 AIM22009.1 - 0.00016 21.9 0.1 0.00044 20.6 0.0 1.8 2 0 0 2 2 2 1 Transcriptional regulator MarR_2 PF12802.7 AIM22009.1 - 0.0014 18.5 0.1 0.0047 16.8 0.1 1.9 1 0 0 1 1 1 1 MarR family HTH_Crp_2 PF13545.6 AIM22009.1 - 0.016 15.2 0.1 0.065 13.2 0.0 2.0 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain Fe_dep_repress PF01325.19 AIM22009.1 - 0.017 15.3 0.0 0.039 14.2 0.0 1.6 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_36 PF13730.6 AIM22009.1 - 0.065 13.2 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.6 AIM22009.1 - 0.16 11.6 0.0 0.33 10.5 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 AIM22009.1 - 0.36 11.0 0.1 0.36 11.0 0.1 2.8 3 1 0 3 3 3 0 Helix-turn-helix domain GATase PF00117.28 AIM22011.1 - 7.1e-12 45.5 0.0 1.1e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AIM22011.1 - 4e-05 23.5 0.2 0.00029 20.7 0.0 2.1 2 0 0 2 2 2 1 Peptidase C26 Phos_pyr_kin PF08543.12 AIM22012.1 - 6.9e-21 74.7 0.0 9.4e-21 74.3 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 AIM22012.1 - 3e-09 36.6 0.0 4.5e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Carb_kinase PF01256.17 AIM22012.1 - 0.004 16.7 0.4 0.0089 15.5 0.4 1.5 1 1 0 1 1 1 1 Carbohydrate kinase YcgR PF07317.12 AIM22013.1 - 1.8e-12 47.0 0.0 3.6e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Flagellar regulator YcgR PilZ PF07238.14 AIM22013.1 - 8.9e-09 35.6 0.0 1.5e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 PilZ domain FGase PF05013.12 AIM22014.1 - 3.6e-39 135.2 0.0 4.3e-39 135.0 0.0 1.1 1 0 0 1 1 1 1 N-formylglutamate amidohydrolase Acetyltransf_5 PF13444.6 AIM22015.1 - 3.4e-23 82.2 0.0 7.2e-23 81.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acyltransferase PF01553.21 AIM22015.1 - 9.4e-13 47.9 0.0 1.8e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase AGTRAP PF06396.11 AIM22015.1 - 0.057 13.2 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Angiotensin II, type I receptor-associated protein (AGTRAP) MlrC_C PF07171.12 AIM22016.1 - 0.13 12.4 0.0 0.14 12.3 0.0 1.0 1 0 0 1 1 1 0 MlrC C-terminus SIS PF01380.22 AIM22017.1 - 6.1e-23 81.1 0.0 9.2e-17 61.1 0.0 2.1 2 0 0 2 2 2 2 SIS domain F_bP_aldolase PF01116.20 AIM22018.1 - 3.7e-96 321.9 0.1 4.5e-96 321.6 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II ThiG PF05690.14 AIM22018.1 - 0.0032 16.8 0.1 0.0059 15.9 0.1 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG SepSecS PF05889.13 AIM22018.1 - 0.13 10.9 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS DUF2574 PF10836.8 AIM22019.1 - 0.035 14.0 0.1 0.04 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2574) DNA_binding_1 PF01035.20 AIM22020.1 - 2e-35 120.7 0.2 3.1e-35 120.2 0.2 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Methyltransf_1N PF02870.15 AIM22020.1 - 1.1e-10 42.2 0.0 1.9e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain cNMP_binding PF00027.29 AIM22021.1 - 3.2e-16 59.2 0.0 7e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HTH_Crp_2 PF13545.6 AIM22021.1 - 3.2e-15 55.8 0.0 5.5e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Crp PF00325.20 AIM22021.1 - 2.1e-14 52.9 0.2 3.8e-14 52.0 0.2 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, crp family MarR_2 PF12802.7 AIM22021.1 - 0.15 12.0 0.0 0.44 10.5 0.0 1.8 1 0 0 1 1 1 0 MarR family Usp PF00582.26 AIM22022.1 - 1e-35 123.3 0.0 2.1e-19 70.5 0.0 2.2 2 0 0 2 2 2 2 Universal stress protein family SBP_bac_3 PF00497.20 AIM22022.1 - 0.16 11.4 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 PNTB PF02233.16 AIM22023.1 - 2e-203 676.5 17.0 2.3e-203 676.3 17.0 1.0 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit TPP_enzyme_M PF00205.22 AIM22023.1 - 0.0083 15.9 0.7 0.075 12.8 0.1 2.8 2 1 1 3 3 3 1 Thiamine pyrophosphate enzyme, central domain AlaDh_PNT_C PF01262.21 AIM22024.1 - 9.3e-76 253.9 2.1 1.4e-75 253.3 2.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 AIM22024.1 - 2e-52 177.1 1.0 3.6e-52 176.3 0.2 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 AIM22024.1 - 1.7e-36 124.5 7.8 5.7e-36 122.8 7.8 2.0 1 0 0 1 1 1 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 AIM22024.1 - 5.5e-05 22.6 0.3 0.067 12.6 0.1 2.6 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 AIM22024.1 - 0.033 13.4 1.3 0.049 12.9 0.4 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF3392 PF11872.8 AIM22024.1 - 0.053 13.8 2.4 0.15 12.4 2.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3392) DUF1471 PF07338.13 AIM22025.1 - 1.7e-65 216.8 2.1 7.2e-21 73.9 0.0 3.5 3 0 0 3 3 3 3 Protein of unknown function (DUF1471) DUF4232 PF14016.6 AIM22025.1 - 0.14 12.3 2.3 0.12 12.6 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4232) AA_permease_2 PF13520.6 AIM22026.1 - 9.8e-73 245.4 34.5 1.2e-72 245.1 34.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 AIM22026.1 - 4.3e-16 58.6 35.6 9.8e-16 57.4 35.6 1.5 1 1 0 1 1 1 1 Amino acid permease Spore_permease PF03845.13 AIM22026.1 - 2.4e-05 23.3 9.7 5.5e-05 22.2 9.7 1.6 1 0 0 1 1 1 1 Spore germination protein BESS PF02944.20 AIM22027.1 - 0.084 12.7 0.2 0.14 12.0 0.2 1.4 1 0 0 1 1 1 0 BESS motif TPR_2 PF07719.17 AIM22027.1 - 1.3 9.3 4.5 0.53 10.5 0.8 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Putative_PNPOx PF01243.20 AIM22028.1 - 5.3e-11 42.6 0.0 7.5e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase adh_short_C2 PF13561.6 AIM22030.1 - 5e-29 101.5 0.1 6.2e-29 101.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AIM22030.1 - 1.2e-25 90.1 0.0 1.6e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AIM22030.1 - 1.9e-08 34.5 0.1 3.9e-08 33.4 0.1 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 AIM22030.1 - 6.8e-06 25.7 0.1 9.8e-05 21.9 0.1 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 AIM22030.1 - 0.00089 18.9 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 AIM22030.1 - 0.013 14.9 0.0 0.66 9.3 0.0 2.4 2 1 1 3 3 3 0 GDP-mannose 4,6 dehydratase Trans_reg_C PF00486.28 AIM22031.1 - 1.3e-20 73.2 0.4 5.5e-20 71.2 0.0 2.0 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal Response_reg PF00072.24 AIM22031.1 - 2.9e-19 69.3 0.0 4.4e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 AIM22032.1 - 1.4e-19 70.7 0.0 2.5e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AIM22032.1 - 5.1e-07 29.6 2.7 6.9e-07 29.2 0.7 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AIM22032.1 - 6.8e-07 29.6 0.0 2.1e-06 28.0 0.0 1.9 1 0 0 1 1 1 1 HAMP domain HATPase_c_2 PF13581.6 AIM22032.1 - 0.0043 17.0 0.0 0.0084 16.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 AIM22032.1 - 0.025 14.4 0.0 0.043 13.6 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AIM22032.1 - 0.21 11.5 0.0 0.41 10.6 0.0 1.4 1 0 0 1 1 1 0 GHKL domain Vpu PF00558.19 AIM22032.1 - 0.45 10.3 3.2 1.3 8.8 0.1 2.6 3 0 0 3 3 3 0 Vpu protein Peptidase_M32 PF02074.15 AIM22033.1 - 9.4e-166 552.4 0.0 1.1e-165 552.2 0.0 1.0 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase DUF2497 PF10691.9 AIM22033.1 - 1.6 9.2 3.7 2.7 8.5 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2497) Abhydrolase_1 PF00561.20 AIM22034.1 - 4.5e-23 82.2 0.0 5.6e-18 65.5 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AIM22034.1 - 5.8e-19 68.3 0.0 3.9e-18 65.6 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AIM22034.1 - 6.6e-14 53.0 7.1 9e-14 52.6 7.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 AIM22034.1 - 0.00063 19.5 0.0 0.0018 18.0 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Esterase PF00756.20 AIM22034.1 - 0.0016 18.1 0.0 0.0023 17.6 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Ndr PF03096.14 AIM22034.1 - 0.003 16.3 0.0 0.016 13.9 0.0 1.8 2 0 0 2 2 2 1 Ndr family Abhydrolase_3 PF07859.13 AIM22034.1 - 0.0031 17.4 0.1 0.0065 16.4 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.9 AIM22034.1 - 0.0053 16.3 0.1 0.24 10.9 0.1 2.2 2 0 0 2 2 2 1 Esterase PHB depolymerase DUF2048 PF09752.9 AIM22034.1 - 0.014 14.5 0.1 0.02 14.0 0.1 1.4 1 1 0 1 1 1 0 Abhydrolase domain containing 18 Thioesterase PF00975.20 AIM22034.1 - 0.042 13.9 0.1 0.08 13.0 0.1 1.4 1 0 0 1 1 1 0 Thioesterase domain Peptidase_S9 PF00326.21 AIM22034.1 - 0.043 13.3 0.0 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 AIM22034.1 - 0.089 12.9 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 TAP-like protein DUF2574 PF10836.8 AIM22035.1 - 0.0026 17.6 0.3 0.0029 17.5 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2574) Asr PF06392.11 AIM22035.1 - 0.08 13.3 34.4 1 9.9 10.3 2.8 2 1 0 2 2 2 0 Acid shock protein repeat Dicty_REP PF05086.12 AIM22035.1 - 0.34 8.8 5.1 0.39 8.6 5.1 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SelP_N PF04592.14 AIM22035.1 - 0.5 9.7 5.7 0.57 9.5 5.7 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Peptidase_S49_N PF08496.10 AIM22035.1 - 1.2 9.2 6.1 1.5 8.9 6.1 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CCDC53 PF10152.9 AIM22035.1 - 2.4 8.6 7.7 3.1 8.2 7.7 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF2561 PF10812.8 AIM22035.1 - 4 7.4 8.2 5.4 7.0 8.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) R_equi_Vir PF05526.11 AIM22035.1 - 5.4 6.8 6.4 6.4 6.6 6.4 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Trypsin PF00089.26 AIM22036.1 - 6.4e-14 52.3 0.0 1.5e-13 51.1 0.0 1.6 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 AIM22036.1 - 3.2e-09 37.9 0.0 4.7e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF5545 PF17699.1 AIM22036.1 - 0.02 14.8 0.1 0.032 14.1 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5545) Rotamase_2 PF13145.6 AIM22036.1 - 0.11 13.4 0.1 0.48 11.3 0.1 2.0 2 0 0 2 2 2 0 PPIC-type PPIASE domain DUF3418 PF11898.8 AIM22037.1 - 1.2e-240 800.2 2.1 1.7e-240 799.7 2.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3418) OB_NTP_bind PF07717.16 AIM22037.1 - 1.3e-18 67.1 0.0 2.6e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 AIM22037.1 - 3.1e-16 59.6 0.0 7.3e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 AIM22037.1 - 3.8e-11 43.3 0.0 1.4e-10 41.5 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 AIM22037.1 - 2.7e-06 27.3 0.1 7.9e-06 25.7 0.1 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 AIM22037.1 - 8.5e-05 21.7 0.0 0.00018 20.6 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 AIM22037.1 - 0.0002 21.7 0.6 0.00073 19.8 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 AIM22037.1 - 0.00021 21.7 0.0 0.00082 19.7 0.0 2.1 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 AIM22037.1 - 0.0011 18.9 2.1 0.0038 17.1 0.6 2.7 2 1 0 2 2 2 1 NACHT domain DUF2075 PF09848.9 AIM22037.1 - 0.011 15.0 0.0 0.048 12.9 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 AIM22037.1 - 0.015 14.7 0.1 0.13 11.7 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_30 PF13604.6 AIM22037.1 - 0.038 13.7 0.0 0.084 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 AIM22037.1 - 0.12 12.4 0.1 20 5.2 0.0 2.7 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit AAA_23 PF13476.6 AIM22037.1 - 0.21 12.0 2.1 0.3 11.6 0.0 2.3 3 0 0 3 3 3 0 AAA domain Flavodoxin_2 PF02525.17 AIM22038.1 - 5.2e-47 160.1 0.0 6e-47 159.9 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 AIM22038.1 - 1.8e-10 40.8 0.0 2.2e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase DUF1318 PF07027.12 AIM22039.1 - 4.5e-29 100.7 2.1 5.8e-29 100.4 2.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1318) PG_binding_3 PF09374.10 AIM22039.1 - 0.018 15.3 0.0 0.023 15.0 0.0 1.3 1 0 0 1 1 1 0 Predicted Peptidoglycan domain NanE PF04131.14 AIM22039.1 - 0.083 12.1 0.0 0.098 11.8 0.0 1.2 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Lipoprotein_19 PF13617.6 AIM22040.1 - 2.5e-18 65.6 3.9 3e-18 65.3 3.9 1.1 1 0 0 1 1 1 1 YnbE-like lipoprotein DctA-YdbH PF11739.8 AIM22041.1 - 4.2e-65 219.4 0.2 1.5e-64 217.5 0.2 2.1 1 0 0 1 1 1 1 Dicarboxylate transport DUF748 PF05359.11 AIM22041.1 - 0.00039 20.6 0.9 0.058 13.6 0.0 3.6 3 0 0 3 3 3 1 Domain of Unknown Function (DUF748) NPR2 PF06218.11 AIM22041.1 - 0.072 11.8 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 Nitrogen permease regulator 2 2-Hacid_dh_C PF02826.19 AIM22042.1 - 3.1e-54 183.0 0.2 5.9e-54 182.1 0.1 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 AIM22042.1 - 5.4e-34 116.7 0.0 8.3e-34 116.1 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 AIM22042.1 - 0.00038 20.7 0.4 0.0018 18.4 0.1 2.1 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase CoA_binding_2 PF13380.6 AIM22042.1 - 0.067 13.7 0.1 0.19 12.2 0.1 1.7 1 1 0 1 1 1 0 CoA binding domain ADH_zinc_N PF00107.26 AIM22042.1 - 0.078 13.0 1.5 2.5 8.1 0.0 3.2 4 0 0 4 4 4 0 Zinc-binding dehydrogenase XdhC_C PF13478.6 AIM22042.1 - 0.081 13.4 0.0 0.26 11.8 0.0 1.9 1 0 0 1 1 1 0 XdhC Rossmann domain META PF03724.16 AIM22043.1 - 8.9e-18 64.2 0.0 1.1e-17 64.0 0.0 1.0 1 0 0 1 1 1 1 META domain DUF333 PF03891.15 AIM22044.1 - 1.1e-11 44.7 0.4 1.9e-11 44.0 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF333) Multi_Drug_Res PF00893.19 AIM22045.1 - 1.2e-27 96.4 10.0 1.6e-27 96.0 10.0 1.1 1 0 0 1 1 1 1 Small Multidrug Resistance protein EamA PF00892.20 AIM22045.1 - 0.00061 20.0 12.8 0.00072 19.7 12.8 1.2 1 0 0 1 1 1 1 EamA-like transporter family TPT PF03151.16 AIM22045.1 - 0.023 14.0 5.8 0.026 13.9 5.8 1.1 1 0 0 1 1 1 0 Triose-phosphate Transporter family LMBR1 PF04791.16 AIM22045.1 - 0.12 11.2 5.8 0.12 11.2 5.4 1.3 1 1 0 1 1 1 0 LMBR1-like membrane protein POR_N PF01855.19 AIM22046.1 - 1.7e-79 266.9 0.5 2.5e-79 266.3 0.5 1.3 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.18 AIM22046.1 - 1e-32 113.7 0.0 2e-32 112.7 0.0 1.4 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase EKR PF10371.9 AIM22046.1 - 7.8e-24 83.2 0.0 1.6e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function PFOR_II PF17147.4 AIM22046.1 - 6.5e-16 58.5 0.1 1.5e-15 57.4 0.1 1.6 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Fer4_7 PF12838.7 AIM22046.1 - 3.7e-10 40.2 9.1 1.1e-09 38.7 9.1 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 AIM22046.1 - 7e-10 39.7 8.3 1.8e-09 38.4 8.3 1.7 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4 PF00037.27 AIM22046.1 - 2.7e-09 36.5 20.4 8.9e-06 25.3 1.2 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_6 PF12837.7 AIM22046.1 - 2.8e-09 36.7 19.9 2.5e-07 30.5 2.9 3.0 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_21 PF14697.6 AIM22046.1 - 4.2e-09 36.4 11.0 6.5e-08 32.6 11.0 2.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain TPP_enzyme_C PF02775.21 AIM22046.1 - 7.5e-09 35.5 0.0 1.8e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4_10 PF13237.6 AIM22046.1 - 1.9e-08 34.3 22.1 2.1e-07 30.9 11.6 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AIM22046.1 - 6.6e-07 29.4 21.0 1.3e-06 28.5 10.4 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_8 PF13183.6 AIM22046.1 - 6e-06 26.6 8.1 1.8e-05 25.1 8.1 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 AIM22046.1 - 2.6e-05 24.0 19.5 0.005 16.9 3.6 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_17 PF13534.6 AIM22046.1 - 3.7e-05 24.2 10.6 4.4e-05 23.9 8.6 2.3 2 1 0 2 2 1 1 4Fe-4S dicluster domain Transketolase_C PF02780.20 AIM22046.1 - 0.009 15.9 0.1 0.034 14.0 0.0 2.0 2 0 0 2 2 2 1 Transketolase, C-terminal domain Fer4_3 PF12798.7 AIM22046.1 - 0.025 15.5 4.8 0.025 15.5 4.8 3.0 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_18 PF13746.6 AIM22046.1 - 0.077 13.2 11.6 0.088 13.0 1.7 2.4 1 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 AIM22046.1 - 0.086 13.4 18.0 0.17 12.5 1.4 3.0 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_13 PF13370.6 AIM22046.1 - 0.13 12.8 11.8 0.3 11.7 0.9 2.8 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 AIM22046.1 - 0.13 13.0 6.0 1.7 9.4 0.3 2.8 2 0 0 2 2 2 0 4Fe-4S single cluster domain ATP_bind_3 PF01171.20 AIM22047.1 - 3.8e-12 46.3 0.0 6e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 PP-loop family Glyoxalase PF00903.25 AIM22048.1 - 1.2e-05 25.5 0.1 2.5e-05 24.5 0.1 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CorA PF01544.18 AIM22049.1 - 1.5e-65 221.5 0.0 1.7e-65 221.2 0.0 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF4381 PF14316.6 AIM22050.1 - 0.014 15.7 1.2 0.062 13.5 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) SBP_bac_5 PF00496.22 AIM22053.1 - 2.1e-89 300.1 10.7 2.9e-89 299.6 10.7 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle DUF4038 PF13204.6 AIM22053.1 - 0.012 15.2 0.2 0.59 9.7 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4038) Myb_DNA-binding PF00249.31 AIM22053.1 - 0.065 13.4 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain YcgR PF07317.12 AIM22054.1 - 0.033 14.0 0.0 0.16 11.9 0.0 1.9 2 0 0 2 2 2 0 Flagellar regulator YcgR DUF3126 PF11324.8 AIM22054.1 - 0.1 12.4 0.2 8.3 6.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3126) Peptidase_M14 PF00246.24 AIM22055.1 - 3e-12 46.9 0.1 6.7e-12 45.8 0.1 1.5 1 1 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 AIM22055.1 - 7.8e-07 28.4 0.0 1.1e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family DUF2817 PF10994.8 AIM22055.1 - 5.1e-06 26.1 0.0 7.1e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) MinC_C PF03775.16 AIM22055.1 - 0.12 12.3 0.1 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 Septum formation inhibitor MinC, C-terminal domain Toprim_3 PF13362.6 AIM22055.1 - 0.13 12.7 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 Toprim domain MR_MLE_C PF13378.6 AIM22056.1 - 7.2e-28 97.7 2.3 1e-27 97.1 2.3 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 AIM22056.1 - 6.4e-19 68.3 0.0 1.3e-18 67.3 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 AIM22056.1 - 0.0089 15.2 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Redoxin PF08534.10 AIM22057.1 - 6.1e-28 97.4 0.0 7.2e-28 97.1 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 AIM22057.1 - 3.7e-13 49.5 0.0 4.4e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Sigma54_activat PF00158.26 AIM22058.1 - 7.7e-63 211.2 0.0 1.2e-62 210.5 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain HTH_50 PF18024.1 AIM22058.1 - 1.6e-21 75.7 0.2 3.4e-21 74.6 0.2 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma54_activ_2 PF14532.6 AIM22058.1 - 1.5e-19 70.5 0.0 3.9e-19 69.1 0.0 1.7 1 1 0 1 1 1 1 Sigma-54 interaction domain PAS_8 PF13188.7 AIM22058.1 - 1.6e-06 28.0 0.0 6.7e-06 26.0 0.0 2.1 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 AIM22058.1 - 2.8e-06 27.3 0.0 1.4e-05 25.1 0.0 2.1 2 0 0 2 2 2 1 PAS fold AAA_5 PF07728.14 AIM22058.1 - 0.00041 20.4 0.0 0.0014 18.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) PAS_4 PF08448.10 AIM22058.1 - 0.0023 18.2 0.0 0.03 14.6 0.0 2.4 2 0 0 2 2 2 1 PAS fold AAA PF00004.29 AIM22058.1 - 0.003 18.0 0.0 0.0094 16.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ACT PF01842.25 AIM22058.1 - 0.0081 15.9 0.1 0.044 13.6 0.0 2.2 2 0 0 2 2 2 1 ACT domain HTH_Tnp_ISL3 PF13542.6 AIM22058.1 - 0.012 15.1 0.0 0.028 13.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_38 PF13936.6 AIM22058.1 - 0.019 14.7 0.2 0.045 13.5 0.2 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain ACT_4 PF13291.6 AIM22058.1 - 0.023 15.3 0.0 0.06 13.9 0.0 1.8 1 0 0 1 1 1 0 ACT domain NUMOD1 PF07453.13 AIM22058.1 - 0.073 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 NUMOD1 domain AAA_2 PF07724.14 AIM22058.1 - 0.12 12.5 0.0 0.34 11.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) PAS_9 PF13426.7 AIM22058.1 - 0.13 12.5 0.0 0.44 10.8 0.0 2.0 1 0 0 1 1 1 0 PAS domain AAA_7 PF12775.7 AIM22058.1 - 0.14 11.6 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF697 PF05128.12 AIM22059.1 - 5.5e-54 182.3 2.6 8.9e-54 181.6 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF697) GspL_C PF12693.7 AIM22059.1 - 5.2 6.9 9.6 0.57 10.0 2.7 2.7 3 1 1 4 4 4 0 GspL periplasmic domain DUF463 PF04317.12 AIM22060.1 - 7.1e-187 621.7 0.0 8e-187 621.6 0.0 1.0 1 0 0 1 1 1 1 YcjX-like family, DUF463 AAA_16 PF13191.6 AIM22060.1 - 0.015 15.7 0.5 1.9 8.9 0.0 3.3 4 0 0 4 4 4 0 AAA ATPase domain DUF1100 PF06500.11 AIM22060.1 - 0.02 13.7 0.0 0.031 13.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) ATPase_2 PF01637.18 AIM22060.1 - 0.053 13.4 0.0 0.13 12.2 0.0 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Phageshock_PspD PF09584.10 AIM22062.1 - 1.9e-16 59.8 2.6 2.2e-16 59.6 2.6 1.0 1 0 0 1 1 1 1 Phage shock protein PspD (Phageshock_PspD) PspC PF04024.12 AIM22063.1 - 2.5e-17 62.4 0.9 3.4e-17 62.0 0.9 1.2 1 0 0 1 1 1 1 PspC domain FixQ PF05545.11 AIM22063.1 - 0.3 11.1 2.8 0.45 10.5 2.8 1.3 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ PspB PF06667.12 AIM22064.1 - 1.8e-33 114.4 2.0 2e-33 114.3 2.0 1.0 1 0 0 1 1 1 1 Phage shock protein B YPEB PF14620.6 AIM22064.1 - 0.0048 16.3 1.5 0.0052 16.2 1.5 1.0 1 0 0 1 1 1 1 YpeB sporulation Rnk_N PF14760.6 AIM22064.1 - 0.0062 17.0 1.4 0.0088 16.5 1.4 1.3 1 0 0 1 1 1 1 Rnk N-terminus P22_AR_C PF10548.9 AIM22064.1 - 0.012 15.8 2.8 0.013 15.6 0.1 1.9 1 1 1 2 2 2 0 P22AR C-terminal domain DUF3886 PF13025.6 AIM22064.1 - 0.036 14.3 1.8 0.05 13.8 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) CcmH PF03918.14 AIM22064.1 - 0.072 12.4 0.4 0.1 11.9 0.4 1.3 1 0 0 1 1 1 0 Cytochrome C biogenesis protein PspA_IM30 PF04012.12 AIM22065.1 - 1.9e-48 165.0 31.4 2.2e-48 164.8 31.4 1.0 1 0 0 1 1 1 1 PspA/IM30 family Filo_VP35 PF02097.15 AIM22065.1 - 0.0079 15.3 0.3 0.011 14.8 0.3 1.4 1 0 0 1 1 1 1 Filoviridae VP35 Tropomyosin PF00261.20 AIM22065.1 - 0.017 14.5 25.5 0.31 10.4 20.8 2.4 1 1 1 2 2 2 0 Tropomyosin Peptidase_C65 PF10275.9 AIM22065.1 - 0.77 9.2 5.7 2.6 7.4 2.0 2.1 1 1 1 2 2 2 0 Peptidase C65 Otubain Retrotrans_gag PF03732.17 AIM22065.1 - 0.93 9.8 6.3 3.6 7.9 0.4 3.2 1 1 2 3 3 3 0 Retrotransposon gag protein DHR10 PF18595.1 AIM22065.1 - 1.1 9.3 27.1 2.1 8.4 7.2 3.1 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Fib_alpha PF08702.10 AIM22065.1 - 1.3 9.2 10.1 1 9.5 6.0 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family V-SNARE PF05008.15 AIM22065.1 - 1.6 9.1 19.0 0.48 10.8 1.5 3.6 1 1 3 4 4 4 0 Vesicle transport v-SNARE protein N-terminus Baculo_PEP_C PF04513.12 AIM22065.1 - 2 8.5 8.3 2.2 8.3 4.2 2.6 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus XhlA PF10779.9 AIM22065.1 - 3.2 8.0 9.7 3.1 8.1 0.2 3.9 4 1 1 5 5 5 0 Haemolysin XhlA DUF1664 PF07889.12 AIM22065.1 - 3.6 7.6 13.1 1.4 8.9 2.5 3.3 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) SlyX PF04102.12 AIM22065.1 - 3.6 8.3 17.1 0.25 12.0 1.6 3.6 2 1 0 3 3 3 0 SlyX YabA PF06156.13 AIM22065.1 - 4.1 8.1 15.6 0.72 10.5 2.1 3.3 2 1 1 3 3 3 0 Initiation control protein YabA Matrilin_ccoil PF10393.9 AIM22065.1 - 7.1 6.6 10.5 2.9 7.8 0.9 3.6 4 0 0 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin Sigma54_activat PF00158.26 AIM22066.1 - 2.8e-61 206.1 0.0 4.1e-61 205.6 0.0 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AIM22066.1 - 1e-21 77.5 0.0 3e-21 76.0 0.0 1.7 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 AIM22066.1 - 4.9e-08 32.6 1.6 1.1e-07 31.6 1.6 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 AIM22066.1 - 3.1e-06 27.2 0.0 6.7e-06 26.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 AIM22066.1 - 7.1e-05 22.3 0.0 0.084 12.2 0.0 2.2 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA PF00004.29 AIM22066.1 - 0.0066 16.9 0.0 0.014 15.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 AIM22066.1 - 0.012 15.8 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) UPF0175 PF03683.13 AIM22066.1 - 0.016 14.9 0.6 0.035 13.8 0.6 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) AAA_7 PF12775.7 AIM22066.1 - 0.046 13.2 0.0 0.073 12.6 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 AIM22066.1 - 0.047 14.1 0.3 0.18 12.2 0.1 2.1 2 1 0 2 2 2 0 AAA ATPase domain HTH_28 PF13518.6 AIM22066.1 - 0.086 13.0 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 AIM22066.1 - 0.095 12.5 0.1 0.24 11.3 0.1 1.7 1 0 0 1 1 1 0 Homeodomain-like domain adh_short PF00106.25 AIM22067.1 - 2.2e-24 86.0 0.0 1.5e-23 83.2 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AIM22067.1 - 8.5e-17 61.5 0.3 3.6e-16 59.4 0.3 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AIM22067.1 - 7.3e-06 26.0 0.5 1.1e-05 25.4 0.5 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AIM22067.1 - 0.00014 21.4 0.0 0.00018 21.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 AIM22067.1 - 0.023 14.6 1.8 0.049 13.5 1.8 1.6 1 1 0 1 1 1 0 NAD(P)H-binding cobW PF02492.19 AIM22068.1 - 5.4e-55 185.7 0.3 6.8e-55 185.4 0.3 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 AIM22068.1 - 1.5e-26 92.1 0.1 3.9e-26 90.8 0.1 1.7 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain MeaB PF03308.16 AIM22068.1 - 0.0045 16.0 0.0 0.015 14.3 0.0 1.8 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB T2SSE PF00437.20 AIM22068.1 - 0.011 14.8 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein RsgA_GTPase PF03193.16 AIM22068.1 - 0.019 14.9 0.1 0.24 11.3 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Viral_helicase1 PF01443.18 AIM22068.1 - 0.081 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 AIM22068.1 - 0.082 12.8 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 AIM22068.1 - 0.084 13.3 0.2 0.18 12.2 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain Branch PF02485.21 AIM22068.1 - 0.086 12.3 0.1 0.53 9.8 0.0 1.9 2 0 0 2 2 2 0 Core-2/I-Branching enzyme MobB PF03205.14 AIM22068.1 - 0.086 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.27 AIM22068.1 - 0.091 13.3 0.0 0.19 12.3 0.0 1.7 1 1 0 1 1 1 0 ABC transporter TsaE PF02367.17 AIM22068.1 - 0.099 12.6 0.1 0.23 11.5 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MMR_HSR1 PF01926.23 AIM22068.1 - 0.11 12.5 0.0 0.23 11.6 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase Hexapep PF00132.24 AIM22069.1 - 1.3e-12 46.9 13.1 0.00019 21.0 0.2 4.4 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 AIM22069.1 - 0.0035 16.4 0.1 0.0045 16.0 0.1 1.1 1 0 0 1 1 1 1 L-fucokinase Hexapep_2 PF14602.6 AIM22069.1 - 1.9 8.3 12.4 0.98 9.2 1.3 4.2 3 2 2 5 5 5 0 Hexapeptide repeat of succinyl-transferase GCHY-1 PF02649.14 AIM22070.1 - 1.3e-63 214.9 0.0 1.5e-63 214.8 0.0 1.0 1 0 0 1 1 1 1 Type I GTP cyclohydrolase folE2 SBP_bac_5 PF00496.22 AIM22071.1 - 2.6e-85 286.7 0.0 3.3e-85 286.3 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle BPD_transp_1 PF00528.22 AIM22072.1 - 7.1e-43 146.5 13.2 7.1e-43 146.5 13.2 2.0 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component MFS_MOT1 PF16983.5 AIM22072.1 - 0.43 11.0 6.4 0.2 12.1 1.5 2.6 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily DUF846 PF05832.12 AIM22072.1 - 3.8 7.5 8.3 0.36 10.9 1.2 2.6 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF846) BPD_transp_1 PF00528.22 AIM22073.1 - 1.7e-23 83.3 11.4 1.7e-23 83.3 11.4 2.2 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 AIM22073.1 - 2e-09 37.3 1.3 2e-09 37.3 1.3 3.5 4 0 0 4 4 4 1 N-terminal TM domain of oligopeptide transport permease C DUF3169 PF11368.8 AIM22073.1 - 0.21 11.1 1.0 0.41 10.1 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) ABC_tran PF00005.27 AIM22074.1 - 3.1e-29 102.2 0.0 1.4e-27 96.9 0.0 2.0 2 0 0 2 2 2 1 ABC transporter oligo_HPY PF08352.12 AIM22074.1 - 6.6e-17 61.8 0.8 1.4e-16 60.8 0.8 1.6 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 AIM22074.1 - 5.3e-08 33.0 0.0 7.9e-06 25.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIM22074.1 - 6.9e-05 22.4 0.0 0.0001 21.8 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AIM22074.1 - 0.0021 18.5 0.0 0.0094 16.3 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AIM22074.1 - 0.0078 16.5 0.7 0.14 12.4 0.7 2.2 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 AIM22074.1 - 0.0099 16.3 0.1 0.21 12.0 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AIM22074.1 - 0.08 12.9 0.1 0.29 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 AIM22074.1 - 0.12 12.3 0.1 0.56 10.1 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase IstB_IS21 PF01695.17 AIM22074.1 - 0.13 12.0 0.0 5.5 6.7 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 AIM22074.1 - 0.14 11.8 0.1 0.62 9.7 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_29 PF13555.6 AIM22074.1 - 0.15 11.8 0.1 0.33 10.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 AIM22075.1 - 5.2e-33 114.5 0.0 7.8e-33 113.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 AIM22075.1 - 1.9e-06 28.2 0.1 8.2e-06 26.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 AIM22075.1 - 1.6e-05 24.4 0.5 0.11 12.0 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AIM22075.1 - 0.00038 20.9 0.1 0.00061 20.2 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.6 AIM22075.1 - 0.00042 20.1 0.0 0.00044 20.1 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AIM22075.1 - 0.00087 19.2 0.2 0.0017 18.3 0.0 1.6 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 AIM22075.1 - 0.0017 18.0 0.1 0.0033 17.1 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 AIM22075.1 - 0.0037 17.1 0.3 0.018 14.8 0.1 2.0 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.9 AIM22075.1 - 0.0066 15.3 0.8 0.13 11.0 0.1 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class DUF3652 PF12372.8 AIM22075.1 - 0.0076 16.1 0.2 0.015 15.2 0.2 1.5 1 0 0 1 1 1 1 Huntingtin protein region DUF87 PF01935.17 AIM22075.1 - 0.0076 16.4 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 Helicase HerA, central domain IstB_IS21 PF01695.17 AIM22075.1 - 0.023 14.4 1.1 0.076 12.7 0.0 2.2 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_13 PF13166.6 AIM22075.1 - 0.029 13.0 0.1 0.73 8.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 AIM22075.1 - 0.03 14.0 0.1 0.091 12.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 AIM22075.1 - 0.038 14.2 0.0 0.074 13.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 AIM22075.1 - 0.039 13.9 0.1 0.085 12.8 0.1 1.5 1 0 0 1 1 1 0 NACHT domain G-alpha PF00503.20 AIM22075.1 - 0.05 12.8 0.0 0.061 12.5 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit ATP-synt_ab PF00006.25 AIM22075.1 - 0.068 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.6 AIM22075.1 - 0.068 13.7 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 AIM22075.1 - 0.075 13.3 0.1 5 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain KH_2 PF07650.17 AIM22075.1 - 0.1 12.5 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 KH domain AAA_18 PF13238.6 AIM22075.1 - 0.11 13.0 0.3 0.98 10.0 0.1 2.4 2 1 0 2 2 2 0 AAA domain oligo_HPY PF08352.12 AIM22075.1 - 0.2 12.2 0.0 0.4 11.2 0.0 1.5 1 0 0 1 1 1 0 Oligopeptide/dipeptide transporter, C-terminal region RNA_helicase PF00910.22 AIM22075.1 - 0.2 12.1 0.0 0.73 10.3 0.0 2.0 2 1 1 3 3 2 0 RNA helicase DLIC PF05783.11 AIM22075.1 - 0.2 10.4 0.1 0.3 9.9 0.1 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) DUF753 PF05444.12 AIM22076.1 - 0.021 14.8 1.4 0.024 14.6 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF753) SatRNA_48 PF17485.2 AIM22076.1 - 0.049 12.8 0.1 0.05 12.7 0.1 1.0 1 0 0 1 1 1 0 Satellite RNA 48 kDa protein CMD PF02627.20 AIM22077.1 - 4e-05 23.6 5.1 0.00012 22.0 0.2 3.7 3 1 1 4 4 4 1 Carboxymuconolactone decarboxylase family LysR_substrate PF03466.20 AIM22078.1 - 7.1e-28 97.4 5.5 8.6e-28 97.1 5.5 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM22078.1 - 9.3e-14 51.1 0.0 1.8e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AIM22078.1 - 0.0042 16.9 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain Peptidase_S11 PF00768.20 AIM22079.1 - 1.1e-91 306.6 0.0 1.5e-91 306.2 0.0 1.1 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase PBP5_C PF07943.13 AIM22079.1 - 1.8e-20 73.0 0.0 3.4e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 Penicillin-binding protein 5, C-terminal domain Beta-lactamase2 PF13354.6 AIM22079.1 - 1.4e-09 37.9 0.0 2e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase enzyme family Beta-lactamase PF00144.24 AIM22079.1 - 1.9e-06 27.3 0.5 2.8e-05 23.5 0.1 2.5 3 0 0 3 3 3 1 Beta-lactamase Molybdopterin PF00384.22 AIM22080.1 - 8e-24 84.4 0.0 1.2e-22 80.5 0.0 2.0 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 AIM22080.1 - 5.7e-14 52.1 0.0 1e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain LysR_substrate PF03466.20 AIM22081.1 - 2.3e-39 134.9 3.0 3.4e-39 134.4 3.0 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM22081.1 - 2.9e-13 49.5 0.1 7.4e-13 48.2 0.0 1.8 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AIM22081.1 - 0.038 13.8 0.4 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain DUF3813 PF12758.7 AIM22081.1 - 0.21 12.0 0.7 0.63 10.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) Glyoxalase PF00903.25 AIM22082.1 - 3e-20 72.7 0.1 3.6e-20 72.4 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 AIM22082.1 - 5.9e-13 49.0 0.0 3.4e-09 37.0 0.0 1.8 1 1 1 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 AIM22082.1 - 9.1e-07 29.2 0.0 0.0069 16.5 0.0 2.3 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_6 PF18029.1 AIM22082.1 - 3.5e-05 24.5 0.0 6.2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 AIM22082.1 - 0.16 11.9 0.0 19 5.2 0.0 2.1 2 0 0 2 2 2 0 Glyoxalase-like domain RNB PF00773.19 AIM22083.1 - 1.2e-83 281.1 0.0 1.5e-83 280.8 0.0 1.1 1 0 0 1 1 1 1 RNB domain OB_RNB PF08206.11 AIM22083.1 - 2.9e-18 65.3 0.0 8.1e-18 63.9 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease B OB domain S1 PF00575.23 AIM22083.1 - 1.4e-11 44.6 0.5 1.4e-09 38.1 0.1 2.4 2 0 0 2 2 2 1 S1 RNA binding domain CSD2 PF17876.1 AIM22083.1 - 8.5e-10 38.7 0.0 9.3e-08 32.1 0.0 2.8 2 0 0 2 2 2 1 Cold shock domain Sugar_tr PF00083.24 AIM22084.1 - 2.7e-26 92.5 27.0 1.6e-18 66.8 9.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 AIM22084.1 - 6e-26 91.2 75.1 3.9e-23 81.9 47.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4181 PF13789.6 AIM22084.1 - 3.5 7.9 5.3 8.2 6.7 0.6 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) Peptidase_M20 PF01546.28 AIM22085.1 - 1.6e-35 122.7 0.4 2e-35 122.4 0.4 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AIM22085.1 - 1.9e-13 50.2 0.1 4.1e-13 49.2 0.1 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF1173 PF06666.11 AIM22085.1 - 0.078 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1173) CstA PF02554.14 AIM22086.1 - 1.1e-172 574.2 23.8 1.1e-172 574.2 23.8 2.2 3 0 0 3 3 3 1 Carbon starvation protein CstA CstA_5TM PF13722.6 AIM22086.1 - 7.2e-33 113.4 8.9 7.2e-33 113.4 8.9 3.4 4 1 0 4 4 4 1 5TM C-terminal transporter carbon starvation CstA DUF2417 PF10329.9 AIM22086.1 - 7.3 5.9 15.4 0.072 12.5 1.3 3.6 4 0 0 4 4 4 0 Region of unknown function (DUF2417) TAL_FSA PF00923.19 AIM22087.1 - 9.1e-44 149.9 0.1 4.9e-43 147.5 0.1 1.9 1 1 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Radical_SAM PF04055.21 AIM22088.1 - 5.7e-27 95.1 0.0 1.3e-26 93.9 0.0 1.6 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 AIM22088.1 - 2.4e-12 47.3 0.3 4.7e-11 43.1 0.3 2.2 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AIM22088.1 - 0.00029 21.0 1.3 0.79 9.9 1.0 2.7 2 1 1 3 3 3 2 4Fe-4S single cluster domain Fer4 PF00037.27 AIM22088.1 - 0.02 14.7 3.6 1.3 9.0 0.8 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.7 AIM22088.1 - 0.082 13.0 3.0 0.88 9.8 0.3 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_7 PF12838.7 AIM22088.1 - 0.21 12.2 5.9 0.45 11.1 3.1 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain PFL-like PF02901.15 AIM22089.1 - 1.9e-201 671.1 0.0 2.4e-201 670.8 0.0 1.0 1 0 0 1 1 1 1 Pyruvate formate lyase-like Gly_radical PF01228.21 AIM22089.1 - 2.2e-29 102.1 0.0 5.7e-29 100.8 0.0 1.8 1 0 0 1 1 1 1 Glycine radical DUF3029 PF11230.8 AIM22089.1 - 0.22 9.8 0.0 0.53 8.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3029) DeoRC PF00455.22 AIM22090.1 - 5e-43 146.8 0.1 7.3e-43 146.3 0.1 1.2 1 0 0 1 1 1 1 DeoR C terminal sensor domain HTH_DeoR PF08220.12 AIM22090.1 - 1.2e-15 56.9 1.1 2.3e-15 56.1 1.1 1.5 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 AIM22090.1 - 5.5e-08 32.6 2.9 2.1e-07 30.8 0.9 2.4 3 0 0 3 3 2 1 HTH domain HTH_Mga PF08280.11 AIM22090.1 - 4.2e-05 23.5 0.4 0.00034 20.6 0.1 2.4 2 0 0 2 2 2 1 M protein trans-acting positive regulator (MGA) HTH domain GntR PF00392.21 AIM22090.1 - 9.1e-05 22.0 0.6 0.00022 20.8 0.6 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Put_DNA-bind_N PF06971.13 AIM22090.1 - 0.00022 21.2 1.5 0.00046 20.1 0.2 2.3 3 0 0 3 3 1 1 Putative DNA-binding protein N-terminus HTH_24 PF13412.6 AIM22090.1 - 0.0017 17.9 3.0 0.015 14.8 0.9 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Rrf2 PF02082.20 AIM22090.1 - 0.0041 17.4 0.8 0.015 15.6 0.2 2.1 2 0 0 2 2 2 1 Transcriptional regulator HTH_AsnC-type PF13404.6 AIM22090.1 - 0.011 15.6 0.4 0.023 14.5 0.4 1.6 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain MarR PF01047.22 AIM22090.1 - 0.016 15.2 0.2 0.033 14.1 0.2 1.6 1 0 0 1 1 1 0 MarR family HTH_36 PF13730.6 AIM22090.1 - 0.016 15.1 0.2 0.14 12.1 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain FeoC PF09012.10 AIM22090.1 - 0.017 15.2 0.2 0.31 11.1 0.0 2.3 2 0 0 2 2 2 0 FeoC like transcriptional regulator MarR_2 PF12802.7 AIM22090.1 - 0.02 14.7 1.1 0.033 14.1 0.4 1.7 2 0 0 2 2 2 0 MarR family FaeA PF04703.12 AIM22090.1 - 0.021 15.2 0.3 0.13 12.7 0.1 2.2 2 0 0 2 2 2 0 FaeA-like protein HTH_IclR PF09339.10 AIM22090.1 - 0.023 14.5 0.2 0.041 13.7 0.2 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 AIM22090.1 - 0.03 14.6 0.1 0.07 13.4 0.1 1.7 1 0 0 1 1 1 0 Transposase DUF977 PF06163.11 AIM22090.1 - 0.043 13.8 0.0 0.08 12.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) HTH_10 PF04967.12 AIM22090.1 - 0.043 13.6 0.1 0.097 12.5 0.1 1.6 1 0 0 1 1 1 0 HTH DNA binding domain HTH_6 PF01418.17 AIM22090.1 - 0.11 12.5 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family Fe_dep_repress PF01325.19 AIM22090.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain RepL PF05732.11 AIM22090.1 - 0.11 11.9 0.1 0.83 9.1 0.0 2.1 1 1 1 2 2 2 0 Firmicute plasmid replication protein (RepL) HTH_5 PF01022.20 AIM22090.1 - 0.15 11.9 0.4 0.74 9.7 0.1 2.1 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family Rick_17kDa_Anti PF05433.15 AIM22091.1 - 3.4e-07 30.0 23.8 4.5e-07 29.6 23.8 1.2 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 AIM22091.1 - 1.3e-06 28.3 17.6 1.8e-06 27.8 17.6 1.3 1 0 0 1 1 1 1 Glycine zipper Gly-zipper_YMGG PF13441.6 AIM22091.1 - 0.00054 19.6 24.2 0.0019 17.9 24.2 1.8 1 1 0 1 1 1 1 YMGG-like Gly-zipper DUF4337 PF14235.6 AIM22091.1 - 0.0051 16.9 0.3 0.0062 16.7 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4337) Gly-zipper_OmpA PF13436.6 AIM22091.1 - 0.12 12.1 25.0 0.55 10.1 25.2 1.8 1 1 0 1 1 1 0 Glycine-zipper domain TraT PF05818.12 AIM22091.1 - 1.5 8.4 5.1 1.5 8.4 5.1 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein SUI1 PF01253.22 AIM22092.1 - 3.2e-19 69.2 0.9 4.2e-19 68.9 0.9 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 OMPdecase PF00215.24 AIM22093.1 - 2e-50 171.5 0.1 2.2e-50 171.3 0.1 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family AP_endonuc_2 PF01261.24 AIM22093.1 - 0.064 12.7 0.2 0.15 11.5 0.1 1.7 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel ATPgrasp_N PF18130.1 AIM22093.1 - 0.066 13.8 1.8 2.6 8.6 0.5 3.1 2 1 0 2 2 2 0 ATP-grasp N-terminal domain Lyase_8_C PF02884.17 AIM22093.1 - 0.12 12.8 0.7 0.57 10.7 0.2 2.0 2 0 0 2 2 2 0 Polysaccharide lyase family 8, C-terminal beta-sandwich domain DUF1471 PF07338.13 AIM22094.1 - 4.7e-17 61.7 0.7 7.5e-17 61.1 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1471) DUF4724 PF15852.5 AIM22094.1 - 0.15 12.6 0.1 0.17 12.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4724) Arc PF03869.14 AIM22095.1 - 0.00058 19.6 0.1 0.00099 18.9 0.1 1.4 1 0 0 1 1 1 1 Arc-like DNA binding domain TPR_19 PF14559.6 AIM22096.1 - 6.1e-14 52.3 10.8 1.4e-07 31.9 1.2 4.0 1 1 2 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 AIM22096.1 - 1.7e-12 46.4 2.7 0.0017 18.3 0.0 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 AIM22096.1 - 7.5e-12 45.7 5.8 0.011 16.3 0.2 4.7 3 1 0 4 4 4 3 Tetratricopeptide repeat Rubredoxin_2 PF18073.1 AIM22096.1 - 1.3e-11 44.0 7.1 2.1e-11 43.3 7.1 1.4 1 0 0 1 1 1 1 Rubredoxin metal binding domain TPR_7 PF13176.6 AIM22096.1 - 1.9e-11 43.1 7.5 0.03 14.3 0.0 5.5 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 AIM22096.1 - 4.7e-10 39.4 17.3 0.3 12.0 0.1 7.5 3 3 5 8 8 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 AIM22096.1 - 2.2e-08 34.3 12.2 0.0048 17.2 0.9 4.2 2 1 1 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 AIM22096.1 - 2.7e-07 30.1 4.1 0.021 14.7 0.1 5.0 6 0 0 6 6 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 AIM22096.1 - 6.6e-07 29.5 2.8 0.00018 21.6 0.7 3.3 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 AIM22096.1 - 1.2e-06 28.2 2.8 0.0092 16.1 0.1 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 AIM22096.1 - 2.6e-05 23.8 0.2 0.018 14.7 0.1 3.3 3 1 1 4 4 3 1 TPR repeat TPR_6 PF13174.6 AIM22096.1 - 0.00022 21.6 13.0 0.36 11.6 0.1 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat ImpA_N PF06812.12 AIM22096.1 - 0.0046 17.1 3.2 0.21 11.7 1.1 2.7 2 0 0 2 2 2 1 ImpA, N-terminal, type VI secretion system TPR_21 PF09976.9 AIM22096.1 - 0.0069 16.1 12.4 0.44 10.2 3.0 2.5 2 1 1 3 3 2 2 Tetratricopeptide repeat-like domain MA3 PF02847.17 AIM22096.1 - 0.0091 16.0 3.1 0.57 10.2 0.1 3.1 4 0 0 4 4 4 1 MA3 domain TPR_9 PF13371.6 AIM22096.1 - 0.024 14.8 3.5 4.4 7.5 1.1 3.1 2 1 1 3 3 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 AIM22096.1 - 0.031 14.2 10.0 7.8 6.5 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.6 AIM22096.1 - 0.033 14.5 14.7 1.4 9.3 0.8 4.9 3 1 2 6 6 6 0 Tetratricopeptide repeat Rapsyn_N PF10579.9 AIM22096.1 - 0.052 13.6 0.2 0.88 9.7 0.0 2.9 2 1 1 3 3 3 0 Rapsyn N-terminal myristoylation and linker region zinc_ribbon_15 PF17032.5 AIM22096.1 - 0.059 14.1 0.1 0.14 12.9 0.1 1.7 1 0 0 1 1 1 0 zinc-ribbon family TPR_17 PF13431.6 AIM22096.1 - 0.081 13.3 0.1 2.6 8.6 0.0 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat Herpes_teg_N PF04843.12 AIM22096.1 - 0.087 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region PPR PF01535.20 AIM22096.1 - 0.11 12.7 4.0 63 4.2 0.0 4.8 6 0 0 6 6 5 0 PPR repeat Synapsin PF02078.16 AIM22096.1 - 0.12 12.7 0.1 0.42 10.9 0.0 2.0 2 0 0 2 2 1 0 Synapsin, N-terminal domain TPR_4 PF07721.14 AIM22096.1 - 0.18 12.5 2.1 1.5e+02 3.5 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat FliT PF05400.13 AIM22096.1 - 0.35 11.7 4.9 0.65 10.8 0.5 2.9 2 0 0 2 2 2 0 Flagellar protein FliT ZZ PF00569.17 AIM22096.1 - 0.37 10.6 3.8 0.69 9.8 3.8 1.4 1 0 0 1 1 1 0 Zinc finger, ZZ type LapA_dom PF06305.11 AIM22097.1 - 3.8e-20 71.5 0.1 3.8e-20 71.5 0.1 2.0 2 0 0 2 2 2 1 Lipopolysaccharide assembly protein A domain Yip1 PF04893.17 AIM22097.1 - 0.0015 18.3 2.4 0.0017 18.1 2.4 1.1 1 0 0 1 1 1 1 Yip1 domain DsbD_2 PF13386.6 AIM22097.1 - 0.0035 17.3 1.6 0.0043 17.0 1.6 1.1 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DUF2304 PF10066.9 AIM22097.1 - 0.024 14.9 2.9 2.3 8.5 0.0 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2304) PhoR PF11808.8 AIM22097.1 - 0.074 13.5 1.6 0.44 11.0 0.1 2.0 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR DUF4389 PF14333.6 AIM22097.1 - 0.17 11.8 3.2 0.62 10.0 1.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4389) HemY_N PF07219.13 AIM22097.1 - 0.62 10.3 3.1 1.2 9.4 0.1 2.1 2 0 0 2 2 2 0 HemY protein N-terminus PAP2 PF01569.21 AIM22098.1 - 1.2e-30 106.1 3.3 1.2e-30 106.1 3.3 2.1 2 1 1 3 3 3 1 PAP2 superfamily GTP_cyclohydro2 PF00925.20 AIM22099.1 - 1.5e-67 226.2 0.0 1.8e-67 226.0 0.0 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase II Aconitase PF00330.20 AIM22100.1 - 2.8e-183 610.2 0.0 3.6e-183 609.8 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 AIM22100.1 - 9.1e-50 168.4 0.0 1.6e-49 167.6 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF4690 PF15756.5 AIM22101.1 - 0.063 13.9 0.2 0.082 13.5 0.2 1.2 1 0 0 1 1 1 0 Small Novel Rich in Cartilage FSAP_sig_propep PF03032.15 AIM22101.1 - 4.9 7.3 6.2 8 6.6 6.2 1.4 1 0 0 1 1 1 0 Frog skin active peptide family signal and propeptide LysR_substrate PF03466.20 AIM22102.1 - 1.7e-41 141.9 0.0 2.4e-41 141.4 0.0 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM22102.1 - 3.8e-15 55.6 0.0 6.5e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family Topoisom_bac PF01131.20 AIM22103.1 - 3.7e-127 424.8 0.6 3.7e-127 424.8 0.6 2.0 3 0 0 3 3 3 1 DNA topoisomerase Topo_Zn_Ribbon PF08272.11 AIM22103.1 - 3e-38 129.2 1.6 4.9e-23 80.5 2.7 2.8 3 0 0 3 3 3 2 Topoisomerase I zinc-ribbon-like Toprim PF01751.22 AIM22103.1 - 8.1e-34 115.9 0.1 2.1e-33 114.6 0.1 1.8 1 0 0 1 1 1 1 Toprim domain zf-C4_Topoisom PF01396.19 AIM22103.1 - 2.7e-19 68.6 16.7 5.4e-12 45.3 3.7 4.4 4 0 0 4 4 4 2 Topoisomerase DNA binding C4 zinc finger Toprim_4 PF13662.6 AIM22103.1 - 0.031 14.7 0.0 0.74 10.3 0.0 2.8 2 0 0 2 2 2 0 Toprim domain Zn_ribbon_recom PF13408.6 AIM22103.1 - 0.58 10.7 12.3 0.7 10.5 0.0 3.5 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain XPA_N PF01286.18 AIM22103.1 - 0.68 10.0 2.1 8.5 6.5 0.1 2.6 2 0 0 2 2 2 0 XPA protein N-terminal DZR PF12773.7 AIM22103.1 - 0.8 9.8 6.2 41 4.3 6.3 2.7 1 1 1 2 2 2 0 Double zinc ribbon DUF2498 PF10692.9 AIM22104.1 - 1.3e-43 146.7 0.1 1.5e-43 146.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2498) Peptidase_S49_N PF08496.10 AIM22105.1 - 8.6e-59 198.0 3.3 1.3e-58 197.4 3.3 1.3 1 0 0 1 1 1 1 Peptidase family S49 N-terminal Peptidase_S49 PF01343.18 AIM22105.1 - 1.2e-45 155.2 0.0 3.8e-45 153.6 0.0 1.8 2 0 0 2 2 2 1 Peptidase family S49 SDH_sah PF01972.16 AIM22105.1 - 0.00037 19.6 0.1 0.00058 18.9 0.1 1.3 1 0 0 1 1 1 1 Serine dehydrogenase proteinase TBD PF12845.7 AIM22105.1 - 0.061 13.2 1.9 9.7 6.2 0.0 2.6 3 0 0 3 3 3 0 TBD domain adh_short PF00106.25 AIM22106.1 - 2.3e-50 170.8 0.0 2.7e-50 170.6 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AIM22106.1 - 1.9e-39 135.6 0.0 3.1e-39 134.9 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AIM22106.1 - 3.4e-15 56.4 0.2 4.5e-15 56.0 0.2 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 AIM22106.1 - 0.0014 18.0 0.0 0.0019 17.6 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 AIM22106.1 - 0.0016 17.6 0.0 0.0021 17.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 AIM22106.1 - 0.021 14.3 0.2 0.11 11.9 0.2 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family CobA_CobO_BtuR PF02572.15 AIM22107.1 - 3.8e-60 203.0 0.3 4.9e-60 202.7 0.3 1.1 1 0 0 1 1 1 1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Co_AT_N PF12557.8 AIM22107.1 - 4.5e-06 26.4 9.1 9.4e-06 25.4 9.1 1.6 1 0 0 1 1 1 1 Cob(I)alamin adenosyltransferase N terminal Smr PF01713.21 AIM22107.1 - 0.038 14.4 1.8 0.87 10.0 0.5 2.4 1 1 0 2 2 2 0 Smr domain Hepar_II_III PF07940.13 AIM22107.1 - 0.048 13.3 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 Heparinase II/III-like protein Moricin PF06451.11 AIM22107.1 - 0.099 12.4 0.2 0.19 11.5 0.2 1.4 1 0 0 1 1 1 0 Moricin PseudoU_synth_2 PF00849.22 AIM22108.1 - 8.4e-18 65.0 0.0 2.5e-17 63.4 0.0 1.8 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 AIM22108.1 - 3.6e-13 49.0 0.2 1.6e-12 46.9 0.2 2.2 1 0 0 1 1 1 1 S4 domain Abhydrolase_1 PF00561.20 AIM22109.1 - 2.1e-12 47.2 0.0 3.3e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AIM22109.1 - 9.4e-12 46.0 8.2 1.1e-11 45.8 8.2 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AIM22109.1 - 2.2e-05 23.9 0.0 2.9e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 AIM22109.1 - 0.2 10.3 0.0 0.33 9.6 0.0 1.3 1 0 0 1 1 1 0 Ndr family Rap1a PF18602.1 AIM22110.1 - 1.4e-06 28.5 0.0 2.4e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Rap1a immunity proteins Sua5_yciO_yrdC PF01300.18 AIM22111.1 - 1.3e-44 151.8 0.0 1.5e-44 151.6 0.0 1.0 1 0 0 1 1 1 1 Telomere recombination Y_Y_Y PF07495.13 AIM22111.1 - 0.21 11.6 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 Y_Y_Y domain PHP PF02811.19 AIM22112.1 - 3.8e-08 33.8 0.0 5e-08 33.4 0.0 1.3 1 1 0 1 1 1 1 PHP domain Chorismate_bind PF00425.18 AIM22113.1 - 3.4e-84 282.4 0.0 5.1e-84 281.9 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 AIM22113.1 - 3.6e-16 59.7 0.0 5.2e-15 55.9 0.0 2.6 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Lipase_GDSL_3 PF14606.6 AIM22113.1 - 0.13 12.4 0.0 0.48 10.5 0.0 1.9 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family T3SS_needle_E PF08988.10 AIM22113.1 - 1.8 8.7 9.2 0.62 10.3 5.4 2.3 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle GATase PF00117.28 AIM22114.1 - 1.2e-43 149.1 0.0 1.4e-43 148.9 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AIM22114.1 - 9.6e-07 28.8 0.2 3.1e-06 27.1 0.2 1.8 1 1 0 1 1 1 1 Peptidase C26 Glyco_transf_4 PF13439.6 AIM22114.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 TrbH PF07283.11 AIM22114.1 - 0.15 12.3 0.0 0.28 11.3 0.0 1.6 1 1 0 1 1 1 0 Conjugal transfer protein TrbH Glycos_transf_3 PF00591.21 AIM22115.1 - 9e-100 333.4 0.0 1.3e-99 333.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 AIM22115.1 - 1.5e-16 60.0 0.9 1.2e-14 53.9 0.2 3.0 3 1 0 3 3 3 2 Glycosyl transferase family, helical bundle domain IGPS PF00218.21 AIM22116.1 - 1.4e-97 325.8 0.0 1.9e-97 325.4 0.0 1.2 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 AIM22116.1 - 6.3e-57 192.5 0.0 8.9e-57 192.0 0.0 1.2 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase PALP PF00291.25 AIM22117.1 - 4.9e-51 173.9 1.1 5.8e-51 173.7 1.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Trp_syntA PF00290.20 AIM22118.1 - 4.3e-97 324.0 0.0 4.8e-97 323.8 0.0 1.0 1 0 0 1 1 1 1 Tryptophan synthase alpha chain NMO PF03060.15 AIM22118.1 - 0.001 18.6 0.1 0.0016 17.9 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 AIM22118.1 - 0.021 14.3 0.0 0.049 13.1 0.0 1.5 2 0 0 2 2 2 0 Histidine biosynthesis protein BON PF04972.17 AIM22119.1 - 1.8e-19 69.8 4.4 2.3e-19 69.4 4.4 1.2 1 0 0 1 1 1 1 BON domain GCV_T PF01571.21 AIM22119.1 - 0.085 12.2 0.1 0.088 12.2 0.1 1.0 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain TolA PF06519.11 AIM22119.1 - 1.3 9.3 4.4 7.4 6.8 2.3 2.1 1 1 1 2 2 2 0 TolA C-terminal OmpW PF03922.14 AIM22120.1 - 5e-64 215.7 0.1 5.7e-64 215.5 0.1 1.0 1 0 0 1 1 1 1 OmpW family OMP_b-brl PF13505.6 AIM22120.1 - 4.3e-15 56.3 4.2 5e-15 56.1 4.2 1.1 1 0 0 1 1 1 1 Outer membrane protein beta-barrel domain OprF PF05736.11 AIM22120.1 - 3.5e-06 26.9 0.1 5.8e-06 26.2 0.1 1.3 1 1 0 1 1 1 1 OprF membrane domain OMP_b-brl_2 PF13568.6 AIM22120.1 - 9.1e-06 25.8 1.3 0.11 12.5 0.0 2.7 2 1 1 3 3 3 2 Outer membrane protein beta-barrel domain Opacity PF02462.15 AIM22120.1 - 0.00084 19.4 0.0 0.0017 18.5 0.0 1.5 1 1 0 1 1 1 1 Opacity family porin protein OmpA_like PF16961.5 AIM22120.1 - 0.0016 18.1 0.0 0.0055 16.4 0.0 1.8 2 0 0 2 2 2 1 Putative OmpA-OmpF-like porin family MtrB_PioB PF11854.8 AIM22120.1 - 0.042 12.2 0.7 0.24 9.7 0.6 1.8 1 1 1 2 2 2 0 Putative outer membrane beta-barrel porin, MtrB/PioB CxxCxxCC PF03692.15 AIM22121.1 - 2.2e-11 44.3 1.4 2.9e-11 43.9 1.4 1.2 1 0 0 1 1 1 1 Putative zinc- or iron-chelating domain Cation_ATPase_N PF00690.26 AIM22121.1 - 0.23 11.2 0.0 0.37 10.5 0.0 1.2 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus UPF0259 PF06790.11 AIM22122.1 - 4.1e-90 301.9 19.5 4.6e-90 301.7 19.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0259) Sulfate_transp PF00916.20 AIM22123.1 - 2.4e-80 270.1 18.6 2.4e-80 270.1 18.6 1.7 1 1 1 2 2 2 1 Sulfate permease family STAS PF01740.21 AIM22123.1 - 6.9e-12 45.0 0.0 1.4e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 STAS domain Cation_ATPase_C PF00689.21 AIM22123.1 - 0.22 11.2 13.6 9.9 5.8 9.0 3.1 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus IspA PF04279.15 AIM22124.1 - 2.6e-70 236.2 24.7 2.9e-70 236.0 24.7 1.0 1 0 0 1 1 1 1 Intracellular septation protein A PrgI PF12666.7 AIM22124.1 - 0.022 15.4 0.5 0.022 15.4 0.5 3.1 2 1 0 2 2 2 0 PrgI family protein TauE PF01925.19 AIM22124.1 - 8 6.0 22.1 5.2 6.6 13.8 2.0 1 1 1 2 2 2 0 Sulfite exporter TauE/SafE 4HBT PF03061.22 AIM22125.1 - 5.8e-19 68.2 0.1 9.1e-19 67.6 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily MaoC_dehydratas PF01575.19 AIM22125.1 - 0.084 12.4 0.1 0.12 11.9 0.1 1.3 1 1 0 1 1 1 0 MaoC like domain TonB_N PF16031.5 AIM22126.1 - 8.5e-23 81.3 61.4 1.1e-22 80.9 61.4 1.2 1 0 0 1 1 1 1 TonB polyproline region TonB_C PF03544.14 AIM22126.1 - 3.6e-18 65.8 0.1 8.2e-18 64.6 0.1 1.6 1 0 0 1 1 1 1 Gram-negative bacterial TonB protein C-terminal TonB_2 PF13103.6 AIM22126.1 - 0.02 15.1 0.3 0.096 12.9 0.0 2.3 2 1 0 2 2 2 0 TonB C terminal Ndc1_Nup PF09531.10 AIM22126.1 - 1.1 7.9 6.4 1.3 7.6 6.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup QueH PF02677.14 AIM22127.1 - 8.1e-64 214.9 0.7 9.3e-64 214.7 0.7 1.0 1 0 0 1 1 1 1 Epoxyqueuosine reductase QueH YCII PF03795.14 AIM22128.1 - 2.5e-30 104.7 0.0 2.8e-30 104.6 0.0 1.0 1 0 0 1 1 1 1 YCII-related domain DUF1330 PF07045.11 AIM22128.1 - 0.0081 16.5 0.2 0.013 15.8 0.2 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1330) HTH_1 PF00126.27 AIM22129.1 - 9.1e-19 67.2 2.4 4.2e-17 61.8 0.4 2.6 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 AIM22129.1 - 1.3e-18 67.2 9.7 2e-18 66.5 9.7 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HemN_C PF06969.16 AIM22129.1 - 0.0049 16.9 0.1 0.026 14.6 0.0 2.2 3 0 0 3 3 3 1 HemN C-terminal domain TPR_19 PF14559.6 AIM22129.1 - 0.15 12.6 1.2 0.47 11.0 0.2 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat EamA PF00892.20 AIM22130.1 - 2.9e-23 82.5 33.8 1.5e-13 51.1 8.8 2.2 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 AIM22130.1 - 0.027 13.8 0.1 0.052 12.9 0.1 1.6 1 1 0 1 1 1 0 Triose-phosphate Transporter family UAA PF08449.11 AIM22130.1 - 0.18 11.0 1.2 0.29 10.3 0.7 1.6 2 0 0 2 2 2 0 UAA transporter family Peripla_BP_4 PF13407.6 AIM22131.1 - 3.5e-22 79.2 0.0 4e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 AIM22131.1 - 6.1e-16 58.7 0.0 7e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_3 PF13377.6 AIM22131.1 - 3.9e-10 40.3 0.0 6.4e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein-like domain DUF2325 PF10087.9 AIM22131.1 - 0.095 12.8 0.0 0.27 11.3 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2325) Lyx_isomer PF07385.12 AIM22132.1 - 2.9e-06 26.7 0.0 4.3e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 D-lyxose isomerase Cupin_2 PF07883.11 AIM22132.1 - 0.02 14.6 0.3 4.4 7.1 0.0 2.6 2 1 0 2 2 2 0 Cupin domain Pkinase PF00069.25 AIM22132.1 - 0.16 11.3 0.0 0.22 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain ADH_N PF08240.12 AIM22133.1 - 3.7e-25 87.9 0.0 8.2e-25 86.8 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AIM22133.1 - 8.2e-19 67.9 0.4 1.3e-18 67.2 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AIM22133.1 - 2.9e-09 38.1 0.0 5.6e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 AIM22133.1 - 1.3e-07 31.3 1.3 4.3e-07 29.6 1.3 1.8 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus UDPG_MGDP_dh_N PF03721.14 AIM22133.1 - 0.14 11.7 0.5 0.24 10.9 0.5 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.24 AIM22133.1 - 0.14 11.7 3.2 0.72 9.4 2.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 AIM22133.1 - 0.16 11.2 1.3 0.3 10.3 1.3 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FGGY_N PF00370.21 AIM22134.1 - 1.7e-66 224.2 0.0 2.4e-66 223.8 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 AIM22134.1 - 2e-27 96.2 0.8 3.7e-27 95.4 0.8 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 AIM22134.1 - 0.00036 20.1 0.3 0.002 17.7 0.1 1.9 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family ABC_tran PF00005.27 AIM22135.1 - 1e-50 171.8 0.0 3.4e-26 92.4 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 AIM22135.1 - 3.6e-10 40.2 2.2 0.00013 21.9 0.0 3.3 2 2 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system NTPase_1 PF03266.15 AIM22135.1 - 0.00065 19.6 0.1 0.03 14.3 0.1 2.3 2 0 0 2 2 2 1 NTPase AAA_29 PF13555.6 AIM22135.1 - 0.00091 18.9 0.2 0.045 13.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_15 PF13175.6 AIM22135.1 - 0.0027 17.5 0.1 0.022 14.5 0.0 1.8 1 1 0 2 2 2 1 AAA ATPase domain CobA_CobO_BtuR PF02572.15 AIM22135.1 - 0.0094 16.2 1.3 0.019 15.2 0.1 2.0 3 0 0 3 3 3 1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP SMC_N PF02463.19 AIM22135.1 - 0.011 15.2 4.4 4.7 6.6 2.0 3.2 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF5030 PF16433.5 AIM22135.1 - 0.02 14.2 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5030) AAA_22 PF13401.6 AIM22135.1 - 0.025 14.8 2.3 20 5.5 1.9 3.1 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 AIM22135.1 - 0.027 14.0 0.2 0.11 12.0 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AIM22135.1 - 0.052 14.0 3.7 0.1 13.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 AIM22135.1 - 0.054 13.4 0.0 0.92 9.4 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_30 PF13604.6 AIM22135.1 - 0.079 12.7 0.0 3.1 7.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 AIM22135.1 - 0.16 12.0 0.3 2.8 8.0 0.3 2.6 2 1 0 2 2 2 0 Dynamin family AAA_33 PF13671.6 AIM22135.1 - 0.25 11.5 1.2 6.4 6.9 0.8 3.0 2 1 0 2 2 2 0 AAA domain BPD_transp_2 PF02653.16 AIM22136.1 - 1.3e-52 178.6 41.1 1.3e-52 178.6 41.1 1.6 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component DUF543 PF04418.12 AIM22136.1 - 0.001 19.0 8.5 0.07 13.1 0.4 3.4 2 1 1 3 3 3 2 Domain of unknown function (DUF543) DUF3671 PF12420.8 AIM22136.1 - 0.62 10.2 2.3 0.76 9.9 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function Peripla_BP_4 PF13407.6 AIM22137.1 - 4.4e-42 144.4 12.6 5.8e-42 144.0 12.6 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 AIM22137.1 - 8.7e-09 35.2 1.8 1.1e-08 34.9 1.8 1.3 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_3 PF13377.6 AIM22137.1 - 2.6e-05 24.6 0.3 6.5e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Periplasmic binding protein-like domain DUF5612 PF18462.1 AIM22137.1 - 0.0068 16.2 0.9 0.019 14.8 0.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5612) PucR PF07905.11 AIM22137.1 - 0.043 14.1 0.1 0.1 12.9 0.0 1.7 2 0 0 2 2 2 0 Purine catabolism regulatory protein-like family OapA PF04225.12 AIM22137.1 - 0.14 12.3 0.3 0.52 10.4 0.1 2.1 2 0 0 2 2 2 0 Opacity-associated protein A LysM-like domain TetR_C_28 PF17937.1 AIM22138.1 - 1.1e-16 61.0 4.6 3.3e-16 59.5 3.8 1.9 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 AIM22138.1 - 4.3e-10 39.2 0.1 9.1e-10 38.2 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family Antirestrict PF03230.13 AIM22138.1 - 0.02 14.9 0.6 0.053 13.6 0.1 1.9 2 1 0 2 2 2 0 Antirestriction protein MFS_1 PF07690.16 AIM22139.1 - 2.6e-50 171.3 42.9 2.6e-50 171.3 42.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 AIM22139.1 - 4e-09 35.9 17.1 4.5e-05 22.5 6.4 3.1 2 2 1 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 AIM22139.1 - 0.0001 21.3 19.2 0.00039 19.4 6.8 2.5 2 0 0 2 2 2 2 MFS_1 like family MFS_2 PF13347.6 AIM22139.1 - 0.00013 20.7 33.2 0.0016 17.1 9.4 2.9 2 1 2 4 4 4 2 MFS/sugar transport protein OATP PF03137.20 AIM22139.1 - 0.36 9.1 6.3 0.11 10.8 0.4 2.5 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Ferritin PF00210.24 AIM22140.1 - 2.7e-28 98.7 1.1 3.1e-28 98.5 1.1 1.0 1 0 0 1 1 1 1 Ferritin-like domain pPIWI_RE_Z PF18155.1 AIM22140.1 - 0.059 13.2 0.0 0.098 12.5 0.0 1.4 1 0 0 1 1 1 0 pPIWI RE three-gene island domain Z VasL PF12486.8 AIM22140.1 - 0.062 13.2 0.1 0.56 10.0 0.0 2.1 2 0 0 2 2 2 0 Type VI secretion system, EvfB, or VasL FliD_C PF07195.12 AIM22140.1 - 0.068 12.6 0.2 0.16 11.3 0.1 1.6 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus PLDc_2 PF13091.6 AIM22142.1 - 2.5e-37 127.7 0.0 3.5e-23 82.0 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 AIM22142.1 - 5.2e-14 51.7 1.6 2.8e-06 27.2 0.0 2.9 3 0 0 3 3 3 2 Phospholipase D Active site motif PLDc_N PF13396.6 AIM22142.1 - 1.2e-07 31.6 2.6 3.4e-07 30.1 2.6 1.8 1 0 0 1 1 1 1 Phospholipase_D-nuclease N-terminal DUF440 PF04269.12 AIM22143.1 - 1.3e-45 153.8 0.2 1.5e-45 153.6 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF440 ABC_tran PF00005.27 AIM22144.1 - 4.6e-31 108.1 0.0 6.5e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 AIM22144.1 - 1.9e-19 69.9 0.2 3.2e-19 69.2 0.2 1.4 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region SMC_N PF02463.19 AIM22144.1 - 8.9e-05 22.0 0.0 0.00014 21.4 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AIM22144.1 - 0.0031 17.4 0.0 1 9.1 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 AIM22144.1 - 0.004 17.4 0.3 0.043 14.1 0.3 2.2 1 1 0 1 1 1 1 AAA domain PRK PF00485.18 AIM22144.1 - 0.0043 16.8 1.0 0.074 12.8 0.1 2.3 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA PF00004.29 AIM22144.1 - 0.035 14.5 0.1 0.071 13.5 0.0 1.5 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 AIM22144.1 - 0.036 14.0 0.2 0.069 13.1 0.2 1.4 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 AIM22144.1 - 0.049 14.0 0.1 0.07 13.5 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 AIM22144.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 AIM22144.1 - 0.069 13.2 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 AIM22144.1 - 0.071 12.9 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 AIM22144.1 - 0.098 13.0 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase MobB PF03205.14 AIM22144.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.6 AIM22144.1 - 0.13 11.9 0.2 1.4 8.4 0.1 2.2 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 AIM22144.1 - 0.14 11.3 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain TniB PF05621.11 AIM22144.1 - 0.19 11.1 0.6 1.3 8.4 0.1 2.1 2 0 0 2 2 2 0 Bacterial TniB protein Sigma54_activat PF00158.26 AIM22144.1 - 0.22 11.2 0.3 0.69 9.6 0.1 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_13 PF13166.6 AIM22144.1 - 0.26 9.9 0.4 0.61 8.7 0.1 1.6 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 AIM22145.1 - 5.4e-28 98.2 0.0 7.1e-28 97.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 AIM22145.1 - 2.2e-21 76.1 0.1 4.2e-21 75.2 0.1 1.5 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 AIM22145.1 - 1.4e-06 28.4 0.9 4.1e-06 26.8 0.0 2.0 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIM22145.1 - 3e-05 23.6 0.0 4.3e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.17 AIM22145.1 - 0.033 13.9 0.1 1.7 8.3 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_29 PF13555.6 AIM22145.1 - 0.052 13.3 1.0 0.094 12.5 0.3 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF87 PF01935.17 AIM22145.1 - 0.35 10.9 1.0 0.61 10.1 0.6 1.6 1 1 1 2 2 2 0 Helicase HerA, central domain BPD_transp_1 PF00528.22 AIM22146.1 - 3.6e-26 92.0 9.6 3.6e-26 92.0 9.6 2.2 1 1 2 3 3 3 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 AIM22146.1 - 1e-13 51.0 0.9 1e-13 51.0 0.9 3.2 4 0 0 4 4 4 1 N-terminal TM domain of oligopeptide transport permease C BPD_transp_1 PF00528.22 AIM22147.1 - 8.5e-39 133.2 17.5 8.5e-39 133.2 17.5 1.8 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component TNT PF14021.6 AIM22147.1 - 0.2 12.2 0.0 0.44 11.1 0.0 1.5 1 0 0 1 1 1 0 Tuberculosis necrotizing toxin TMEM18 PF14770.6 AIM22147.1 - 3.8 7.5 5.4 6.5 6.8 0.8 2.6 2 0 0 2 2 2 0 Transmembrane protein 18 SBP_bac_5 PF00496.22 AIM22148.1 - 3.2e-89 299.5 10.8 4.2e-89 299.2 10.8 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle GH115_C PF17829.1 AIM22148.1 - 0.049 13.5 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 Gylcosyl hydrolase family 115 C-terminal domain SBP_bac_5 PF00496.22 AIM22149.1 - 2.4e-84 283.5 7.9 2.9e-84 283.2 7.9 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle MarC PF01914.17 AIM22150.1 - 2.2e-73 246.0 10.2 2.4e-73 245.9 10.2 1.0 1 0 0 1 1 1 1 MarC family integral membrane protein LysE PF01810.18 AIM22150.1 - 0.28 10.6 10.4 2.2 7.7 10.4 2.2 1 1 0 1 1 1 0 LysE type translocator DUF4870 PF09685.10 AIM22150.1 - 0.5 10.5 11.1 0.07 13.2 1.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4870) DUF3087 PF11286.8 AIM22150.1 - 3.2 7.2 5.4 6 6.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) PNTB_4TM PF12769.7 AIM22150.1 - 6.4 7.3 9.0 18 5.8 0.1 3.0 3 0 0 3 3 3 0 4TM region of pyridine nucleotide transhydrogenase, mitoch Fe-ADH PF00465.19 AIM22151.1 - 2e-116 388.8 0.2 3.1e-116 388.2 0.2 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Aldedh PF00171.22 AIM22151.1 - 2.2e-29 102.3 2.3 3.9e-28 98.2 2.3 2.1 1 1 0 1 1 1 1 Aldehyde dehydrogenase family Fe-ADH_2 PF13685.6 AIM22151.1 - 3.1e-18 66.4 0.1 1.1e-07 31.8 0.5 2.6 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase HTH_AsnC-type PF13404.6 AIM22151.1 - 0.055 13.3 0.2 0.36 10.7 0.0 2.4 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain TK PF00265.18 AIM22152.1 - 4.4e-62 209.1 0.2 5e-62 208.9 0.2 1.0 1 0 0 1 1 1 1 Thymidine kinase AAA_22 PF13401.6 AIM22152.1 - 4.4e-05 23.8 0.0 7.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain KdpD PF02702.17 AIM22152.1 - 0.08 12.4 0.1 0.2 11.1 0.0 1.6 2 0 0 2 2 2 0 Osmosensitive K+ channel His kinase sensor domain AAA_30 PF13604.6 AIM22152.1 - 0.11 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Histone_HNS PF00816.21 AIM22153.1 - 8.5e-19 68.2 7.1 8.5e-19 68.2 7.1 1.9 1 1 1 2 2 2 1 H-NS histone family DUF3037 PF11236.8 AIM22153.1 - 0.0045 17.4 1.6 0.006 17.0 1.4 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3037) TetR_C_24 PF17932.1 AIM22153.1 - 0.022 15.0 1.1 0.032 14.5 1.1 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain PaaX_C PF08223.11 AIM22153.1 - 0.024 14.9 0.2 0.034 14.4 0.2 1.3 1 0 0 1 1 1 0 PaaX-like protein C-terminal domain Spem1 PF15670.5 AIM22153.1 - 0.076 12.6 0.0 0.084 12.4 0.0 1.0 1 0 0 1 1 1 0 Spermatid maturation protein 1 GDP_Man_Dehyd PF16363.5 AIM22154.1 - 6.6e-59 200.0 0.0 7.8e-59 199.7 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 AIM22154.1 - 4.1e-55 186.9 0.0 4.9e-55 186.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 AIM22154.1 - 3.7e-18 65.5 0.0 4.8e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 AIM22154.1 - 9.9e-14 51.1 0.0 1.2e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 AIM22154.1 - 3e-10 39.7 0.0 2.1e-09 36.9 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 AIM22154.1 - 2e-07 31.1 0.0 1.2e-06 28.6 0.0 2.2 2 1 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 AIM22154.1 - 4.5e-06 26.0 0.0 0.013 14.7 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein adh_short PF00106.25 AIM22154.1 - 4.9e-06 26.1 0.1 3.7e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 AIM22154.1 - 0.0015 18.1 0.0 0.0036 16.9 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AIM22154.1 - 0.017 15.0 0.1 0.083 12.8 0.1 2.0 1 1 0 1 1 1 0 KR domain NmrA PF05368.13 AIM22154.1 - 0.077 12.5 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family UDPG_MGDP_dh_N PF03721.14 AIM22155.1 - 1.4e-65 220.4 1.1 2.4e-65 219.6 1.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 AIM22155.1 - 1.2e-39 134.4 0.0 2.6e-39 133.3 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 AIM22155.1 - 8e-31 106.6 0.0 2.6e-30 104.9 0.0 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_binding_2 PF03446.15 AIM22155.1 - 0.00014 22.0 0.7 0.022 14.9 0.9 3.2 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 AIM22155.1 - 0.0005 20.0 0.1 0.0013 18.7 0.1 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 AIM22155.1 - 0.0021 17.4 0.6 0.0039 16.5 0.6 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 AIM22155.1 - 0.004 17.4 1.2 0.044 14.1 0.1 2.9 3 1 0 3 3 3 1 TrkA-N domain NAD_binding_11 PF14833.6 AIM22155.1 - 0.0078 16.4 0.1 0.36 11.1 0.0 2.6 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase ApbA PF02558.16 AIM22155.1 - 0.0094 15.6 0.1 0.023 14.4 0.1 1.7 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 AIM22155.1 - 0.022 15.2 0.2 0.98 9.9 0.1 2.7 2 1 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox PF00070.27 AIM22155.1 - 0.071 13.7 1.6 0.31 11.6 0.3 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 AIM22155.1 - 0.074 13.0 0.1 0.21 11.5 0.1 2.0 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_3 PF01494.19 AIM22155.1 - 0.083 12.1 0.1 0.16 11.2 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain NTP_transferase PF00483.23 AIM22156.1 - 1.8e-24 86.7 0.0 2.4e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AIM22156.1 - 7.2e-08 32.9 0.0 1.3e-07 32.1 0.0 1.5 1 1 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 AIM22156.1 - 0.0045 16.8 0.0 0.0069 16.1 0.0 1.3 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP_transf_3 PF02348.19 AIM22156.1 - 0.05 13.5 0.2 0.099 12.5 0.1 1.5 2 0 0 2 2 2 0 Cytidylyltransferase PHZA_PHZB PF03284.13 AIM22156.1 - 0.074 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Phenazine biosynthesis protein A/B Response_reg PF00072.24 AIM22157.1 - 2.2e-26 92.2 0.1 5.7e-26 90.9 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain MRP_L53 PF10780.9 AIM22157.1 - 0.11 12.7 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 39S ribosomal protein L53/MRP-L53 Patatin PF01734.22 AIM22158.1 - 3.2e-22 79.7 2.2 2.9e-21 76.6 2.2 2.1 1 1 0 1 1 1 1 Patatin-like phospholipase UPF0225 PF17775.1 AIM22159.1 - 3.3e-32 111.2 0.0 3.9e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 UPF0225 domain SEC-C PF02810.15 AIM22159.1 - 3.8e-15 55.5 22.8 1.5e-09 37.6 10.3 2.4 2 0 0 2 2 2 2 SEC-C motif Formyl_trans_N PF00551.19 AIM22160.1 - 4.3e-55 186.2 0.1 5.4e-55 185.9 0.1 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.25 AIM22160.1 - 3.9e-07 29.7 0.0 1.1e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 ACT domain Lysine_decarbox PF03641.14 AIM22161.1 - 7.1e-41 139.4 0.0 8.4e-41 139.2 0.0 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 AIM22161.1 - 5.6e-17 61.8 0.0 6.5e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 SLOG cluster4 family Exo_endo_phos PF03372.23 AIM22162.1 - 1.7e-24 86.7 0.2 2e-24 86.4 0.2 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 AIM22162.1 - 0.011 15.6 0.0 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase NUDIX PF00293.28 AIM22163.1 - 2.1e-20 73.1 0.1 2.3e-20 73.0 0.1 1.0 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 AIM22163.1 - 5.8e-14 52.0 0.1 6.8e-14 51.8 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.6 AIM22163.1 - 0.1 12.1 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Nucleotide hydrolase DUF1496 PF07383.12 AIM22164.1 - 1.6e-21 75.6 0.4 1.9e-21 75.4 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1496) Topoisom_bac PF01131.20 AIM22165.1 - 5.7e-111 371.5 0.0 7.1e-111 371.1 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 AIM22165.1 - 7.6e-18 64.6 0.0 1.6e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 Toprim domain AAA_16 PF13191.6 AIM22166.1 - 0.00016 22.1 0.5 0.00039 20.8 0.5 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AIM22166.1 - 0.058 13.7 0.1 0.16 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain Rhodanese PF00581.20 AIM22166.1 - 0.078 13.5 0.1 0.65 10.5 0.1 2.4 1 1 0 1 1 1 0 Rhodanese-like domain T2SSE PF00437.20 AIM22166.1 - 0.091 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein VacA PF02691.15 AIM22166.1 - 0.14 10.0 0.2 0.17 9.7 0.2 1.1 1 0 0 1 1 1 0 Vacuolating cyotoxin AIRS_C PF02769.22 AIM22167.1 - 9.6e-27 94.0 0.2 1.4e-26 93.5 0.2 1.2 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 AIM22167.1 - 1.2e-18 67.5 2.0 1.4e-18 67.3 0.8 1.7 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain Nitroreductase PF00881.24 AIM22168.1 - 1.3e-20 74.2 0.4 1.5e-20 73.9 0.4 1.1 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 AIM22168.1 - 0.072 12.6 0.1 11 5.5 0.0 2.1 2 0 0 2 2 2 0 Putative TM nitroreductase Peptidase_S49 PF01343.18 AIM22169.1 - 5.4e-90 299.3 0.2 2.1e-50 170.7 0.1 2.5 3 0 0 3 3 3 2 Peptidase family S49 CLP_protease PF00574.23 AIM22169.1 - 0.00062 19.7 0.1 0.016 15.1 0.1 2.3 2 0 0 2 2 2 1 Clp protease ECH_1 PF00378.20 AIM22169.1 - 0.0091 15.3 1.4 0.18 11.1 0.2 2.9 3 1 0 3 3 3 1 Enoyl-CoA hydratase/isomerase SDH_sah PF01972.16 AIM22169.1 - 0.023 13.7 0.0 0.047 12.7 0.0 1.4 1 0 0 1 1 1 0 Serine dehydrogenase proteinase Asparaginase PF00710.20 AIM22170.1 - 3.8e-65 219.0 0.0 6.5e-65 218.3 0.0 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 AIM22170.1 - 2e-32 111.8 0.1 4.6e-32 110.6 0.1 1.6 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Isochorismatase PF00857.20 AIM22171.1 - 9.9e-35 120.3 0.0 1.3e-34 119.9 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family 3HCDH_RFF PF18321.1 AIM22171.1 - 0.13 12.7 2.5 0.62 10.6 0.3 2.8 3 0 0 3 3 3 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain DUF3197 PF11432.8 AIM22171.1 - 0.15 11.9 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3197) Flavi_NS5 PF00972.20 AIM22171.1 - 0.19 9.8 0.0 0.25 9.4 0.0 1.1 1 0 0 1 1 1 0 Flavivirus RNA-directed RNA polymerase Glyco_hydro_18 PF00704.28 AIM22172.1 - 1.2e-66 225.7 0.2 1.4e-66 225.4 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF1315 PF07023.12 AIM22173.1 - 2.2e-26 91.8 0.2 2.4e-26 91.6 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1315) SelR PF01641.18 AIM22174.1 - 7.8e-52 174.5 0.1 9.3e-52 174.2 0.1 1.0 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.14 AIM22174.1 - 0.0053 17.0 0.5 0.013 15.7 0.5 1.7 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Gp_dh_C PF02800.20 AIM22175.1 - 7.2e-72 240.1 0.0 1e-71 239.6 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 AIM22175.1 - 5.3e-42 142.3 1.9 1.4e-41 140.9 0.5 2.1 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 AIM22175.1 - 0.00041 20.5 1.7 0.0027 17.8 1.7 2.3 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 AIM22175.1 - 0.022 14.1 0.0 0.067 12.5 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Aldose_epim PF01263.20 AIM22176.1 - 4.6e-44 150.9 0.0 5.7e-44 150.6 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase MipA PF06629.12 AIM22177.1 - 2e-53 181.8 10.3 2.2e-53 181.7 10.3 1.0 1 0 0 1 1 1 1 MltA-interacting protein MipA AAA_PrkA PF08298.11 AIM22178.1 - 1.4e-176 586.7 0.0 2.1e-176 586.1 0.0 1.2 1 0 0 1 1 1 1 PrkA AAA domain PrkA PF06798.12 AIM22178.1 - 2.2e-72 243.8 2.3 3.9e-72 243.0 2.3 1.4 1 0 0 1 1 1 1 PrkA serine protein kinase C-terminal domain AAA_16 PF13191.6 AIM22178.1 - 4.5e-05 23.9 0.0 0.00019 21.9 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 AIM22178.1 - 0.0032 17.5 0.2 0.034 14.2 0.1 2.6 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 AIM22178.1 - 0.0066 16.7 0.0 0.033 14.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain HEPN PF05168.14 AIM22178.1 - 0.09 12.9 0.0 0.52 10.4 0.1 2.3 2 0 0 2 2 2 0 HEPN domain Mg_chelatase PF01078.21 AIM22178.1 - 0.13 11.6 0.0 0.37 10.1 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF444 PF04285.12 AIM22179.1 - 7.3e-187 621.6 3.5 8.2e-187 621.4 3.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF444) HALZ PF02183.18 AIM22179.1 - 0.43 10.9 3.7 22 5.3 0.0 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper End3 PF12761.7 AIM22179.1 - 5.5 7.1 8.4 1.3 9.2 1.0 2.6 2 1 1 3 3 3 0 Actin cytoskeleton-regulatory complex protein END3 RskA PF10099.9 AIM22180.1 - 2.6e-21 76.7 1.4 6.4e-21 75.5 1.4 1.6 1 1 0 1 1 1 1 Anti-sigma-K factor rskA Sigma70_r2 PF04542.14 AIM22181.1 - 1.7e-16 59.7 0.2 1.7e-16 59.7 0.2 1.9 3 0 0 3 3 3 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 AIM22181.1 - 3.4e-13 49.0 0.0 6e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AIM22181.1 - 7.4e-11 41.4 0.0 1.9e-10 40.1 0.0 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 AIM22181.1 - 1.3e-08 34.5 0.4 2.4e-06 27.2 0.0 2.6 2 0 0 2 2 2 2 Helix-turn-helix domain Sigma70_ECF PF07638.11 AIM22181.1 - 2.2e-05 24.4 0.1 5.6e-05 23.1 0.1 1.6 1 1 0 1 1 1 1 ECF sigma factor HTH_23 PF13384.6 AIM22181.1 - 6.6e-05 22.6 0.1 0.00014 21.5 0.1 1.6 1 0 0 1 1 1 1 Homeodomain-like domain Terminase_5 PF06056.12 AIM22181.1 - 0.0068 16.3 0.1 0.013 15.3 0.1 1.4 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) B12-binding_2 PF02607.17 AIM22181.1 - 0.1 13.0 0.0 0.34 11.4 0.0 1.8 2 0 0 2 2 2 0 B12 binding domain Fasciclin PF02469.22 AIM22182.1 - 1.9e-30 105.7 0.0 2.5e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 Fasciclin domain YmgB PF10798.8 AIM22183.1 - 0.00022 21.0 0.2 0.00032 20.4 0.2 1.2 1 0 0 1 1 1 1 Biofilm development protein YmgB/AriR DUF2767 PF10965.8 AIM22183.1 - 0.069 13.2 0.0 0.088 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2767) Abhydrolase_6 PF12697.7 AIM22184.1 - 2.1e-19 71.0 3.0 2.6e-19 70.7 3.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 AIM22184.1 - 3.2e-07 30.4 0.3 0.00033 20.6 0.0 2.1 2 0 0 2 2 2 2 Serine hydrolase Hydrolase_4 PF12146.8 AIM22184.1 - 3.1e-06 26.6 1.2 0.0059 15.9 1.2 3.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AIM22184.1 - 2.1e-05 24.3 0.7 0.014 15.1 0.4 3.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 AIM22184.1 - 2.4e-05 24.2 0.0 5.7e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.20 AIM22184.1 - 0.00045 20.4 0.4 0.0012 19.0 0.4 1.8 1 1 0 1 1 1 1 Thioesterase domain DLH PF01738.18 AIM22184.1 - 0.059 12.9 0.1 0.39 10.2 0.0 2.3 2 1 1 3 3 3 0 Dienelactone hydrolase family DUF676 PF05057.14 AIM22184.1 - 0.28 10.6 1.0 1.9 8.0 0.1 2.2 1 1 0 2 2 2 0 Putative serine esterase (DUF676) Toxin_GhoT_OrtT PF10753.9 AIM22185.1 - 6.2e-20 71.2 6.7 6.8e-20 71.1 6.7 1.0 1 0 0 1 1 1 1 Toxin GhoT_OrtT DUF3392 PF11872.8 AIM22188.1 - 0.0028 17.9 0.3 0.0032 17.7 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3392) DUF2427 PF10348.9 AIM22188.1 - 0.0041 16.9 0.1 0.005 16.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) DUF5051 PF16473.5 AIM22189.1 - 6.9e-47 159.5 0.0 7.8e-47 159.3 0.0 1.0 1 0 0 1 1 1 1 3' exoribonuclease, RNase T-like RNase_T PF00929.24 AIM22189.1 - 0.003 18.1 0.0 0.0057 17.2 0.0 1.5 1 1 0 1 1 1 1 Exonuclease RNase_H_2 PF13482.6 AIM22189.1 - 0.15 12.0 0.0 4.1 7.4 0.0 2.2 1 1 0 1 1 1 0 RNase_H superfamily MFS_1 PF07690.16 AIM22190.1 - 5.4e-42 144.0 45.7 5.4e-42 144.0 45.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 AIM22190.1 - 1e-09 37.8 27.5 5.7e-08 32.1 6.5 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 AIM22190.1 - 0.0029 16.1 2.4 0.005 15.3 2.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2964 PF11177.8 AIM22190.1 - 3 8.1 8.2 0.86 9.8 1.4 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2964) Ala_racemase_N PF01168.20 AIM22191.1 - 2.5e-67 226.7 0.3 3.2e-67 226.4 0.3 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Ala_racemase_C PF00842.21 AIM22191.1 - 2.1e-38 130.9 0.1 3.1e-38 130.4 0.1 1.3 1 0 0 1 1 1 1 Alanine racemase, C-terminal domain DAO PF01266.24 AIM22192.1 - 9.5e-74 249.1 0.4 1.1e-73 248.8 0.4 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 AIM22192.1 - 1e-08 35.6 0.1 2.2e-05 24.9 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 AIM22192.1 - 1.5e-08 34.2 0.2 0.00011 21.6 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AIM22192.1 - 4.5e-08 33.2 0.0 1.4e-06 28.4 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 AIM22192.1 - 1.6e-07 30.7 1.9 0.0053 15.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 AIM22192.1 - 2.5e-06 26.5 1.0 0.025 13.3 0.0 2.7 3 0 0 3 3 3 2 HI0933-like protein ApbA PF02558.16 AIM22192.1 - 3.5e-06 26.7 0.2 4.6e-05 23.1 0.1 2.4 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 AIM22192.1 - 4.9e-05 22.6 0.4 0.064 12.3 0.4 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 AIM22192.1 - 0.00012 21.6 2.9 0.17 11.2 0.0 2.6 1 1 1 2 2 2 2 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 AIM22192.1 - 0.00019 21.1 0.1 0.00038 20.1 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Amino_oxidase PF01593.24 AIM22192.1 - 0.00048 19.5 0.0 0.072 12.4 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 AIM22192.1 - 0.0006 19.2 0.1 0.00097 18.5 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 AIM22192.1 - 0.00061 18.8 1.8 0.61 8.9 0.1 2.5 2 0 0 2 2 2 2 Tryptophan halogenase 3HCDH_N PF02737.18 AIM22192.1 - 0.0014 18.5 0.5 0.0028 17.6 0.1 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 AIM22192.1 - 0.0024 17.2 0.4 0.0056 16.0 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain GDI PF00996.18 AIM22192.1 - 0.0036 15.9 0.0 0.016 13.7 0.0 1.8 2 0 0 2 2 2 1 GDP dissociation inhibitor Thi4 PF01946.17 AIM22192.1 - 0.021 14.1 0.1 0.27 10.5 0.1 2.1 2 0 0 2 2 2 0 Thi4 family Glyco_transf_4 PF13439.6 AIM22192.1 - 0.024 14.6 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Pyr_redox_3 PF13738.6 AIM22192.1 - 0.027 13.7 0.1 2.4 7.3 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 AIM22192.1 - 0.044 14.4 0.0 0.13 12.9 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 AIM22192.1 - 0.062 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain XdhC_C PF13478.6 AIM22192.1 - 0.068 13.7 0.0 0.24 11.9 0.0 1.9 2 0 0 2 2 2 0 XdhC Rossmann domain Sacchrp_dh_NADP PF03435.18 AIM22192.1 - 0.087 13.1 0.2 0.19 12.0 0.1 1.6 2 0 0 2 2 1 0 Saccharopine dehydrogenase NADP binding domain NAD_Gly3P_dh_N PF01210.23 AIM22192.1 - 0.11 12.4 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ABM PF03992.16 AIM22193.1 - 6.5e-09 35.8 0.1 8.4e-09 35.4 0.1 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase SOR PF07682.11 AIM22193.1 - 0.093 11.6 0.0 0.094 11.6 0.0 1.1 1 0 0 1 1 1 0 Sulphur oxygenase reductase ZinT PF09223.11 AIM22194.1 - 1.1e-84 282.8 3.2 1.3e-84 282.6 3.2 1.0 1 0 0 1 1 1 1 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment SpoVR PF04293.13 AIM22195.1 - 9.9e-177 587.8 10.5 1.2e-176 587.5 10.5 1.0 1 0 0 1 1 1 1 SpoVR like protein Peptidase_M1 PF01433.20 AIM22195.1 - 0.033 13.8 0.1 0.073 12.6 0.1 1.5 1 0 0 1 1 1 0 Peptidase family M1 domain TraG-D_C PF12696.7 AIM22195.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG FadR_C PF07840.12 AIM22196.1 - 3.9e-73 244.7 0.0 4.6e-73 244.5 0.0 1.0 1 0 0 1 1 1 1 FadR C-terminal domain GntR PF00392.21 AIM22196.1 - 1.2e-08 34.4 0.1 2.4e-08 33.5 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family FCD PF07729.12 AIM22196.1 - 0.0013 19.2 0.0 0.0053 17.2 0.0 2.0 2 1 1 3 3 3 1 FCD domain HTH_Crp_2 PF13545.6 AIM22196.1 - 0.005 16.8 0.0 0.0088 16.0 0.0 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Exotox-A_target PF09102.10 AIM22196.1 - 0.0074 16.3 0.1 0.014 15.3 0.1 1.4 1 0 0 1 1 1 1 Exotoxin A, targeting TrmB PF01978.19 AIM22196.1 - 0.01 15.7 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DASH_Ask1 PF08655.10 AIM22196.1 - 0.027 14.3 0.0 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 DASH complex subunit Ask1 B PF02216.16 AIM22196.1 - 0.083 12.9 0.1 0.2 11.6 0.1 1.6 1 1 0 1 1 1 0 B domain PaaX PF07848.12 AIM22196.1 - 0.12 12.6 0.4 0.25 11.6 0.0 1.7 2 0 0 2 2 2 0 PaaX-like protein NhaB PF06450.12 AIM22197.1 - 7.2e-276 915.9 23.6 8.2e-276 915.8 23.6 1.0 1 0 0 1 1 1 1 Bacterial Na+/H+ antiporter B (NhaB) CitMHS PF03600.16 AIM22197.1 - 8.4e-07 28.5 42.8 0.0061 15.8 3.4 3.2 2 2 1 3 3 3 3 Citrate transporter DsbB PF02600.16 AIM22198.1 - 7.8e-46 156.1 14.0 9.4e-46 155.9 14.0 1.0 1 0 0 1 1 1 1 Disulfide bond formation protein DsbB DPM3 PF08285.11 AIM22198.1 - 3.1 8.1 10.2 1.5 9.0 5.0 2.5 2 1 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Asp_Arg_Hydrox PF05118.15 AIM22199.1 - 2e-50 170.7 0.1 2.6e-50 170.3 0.1 1.1 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Cupin_2 PF07883.11 AIM22199.1 - 0.015 15.0 0.1 0.053 13.2 0.0 1.9 2 0 0 2 2 2 0 Cupin domain CxxCxxCC PF03692.15 AIM22200.1 - 1.7e-07 31.8 10.2 3.1e-07 31.0 10.2 1.5 1 0 0 1 1 1 1 Putative zinc- or iron-chelating domain FAA_hydrolase PF01557.18 AIM22201.1 - 6.3e-53 179.7 0.0 7.3e-53 179.4 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family SLT_2 PF13406.6 AIM22202.1 - 1.7e-104 349.1 0.3 2e-104 348.9 0.3 1.0 1 0 0 1 1 1 1 Transglycosylase SLT domain Glucosaminidase PF01832.20 AIM22202.1 - 0.047 14.2 0.0 0.094 13.2 0.0 1.7 1 1 0 1 1 1 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase YcgL PF05166.13 AIM22203.1 - 4.3e-34 116.7 0.4 5.1e-34 116.4 0.4 1.1 1 0 0 1 1 1 1 YcgL domain RACo_linker PF17650.1 AIM22203.1 - 0.11 12.4 0.0 4.2 7.3 0.0 2.1 1 1 1 2 2 2 0 RACo linker region MinC_N PF05209.13 AIM22204.1 - 1.3e-34 118.3 0.0 1.8e-34 117.8 0.0 1.2 1 0 0 1 1 1 1 Septum formation inhibitor MinC, N-terminal domain MinC_C PF03775.16 AIM22204.1 - 1.5e-31 108.4 0.1 3e-31 107.4 0.1 1.5 1 0 0 1 1 1 1 Septum formation inhibitor MinC, C-terminal domain AAA_31 PF13614.6 AIM22205.1 - 8e-21 74.7 0.2 1.5e-20 73.9 0.2 1.4 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 AIM22205.1 - 3.8e-20 72.3 0.1 5.1e-20 71.8 0.1 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 AIM22205.1 - 1.1e-16 61.0 0.7 1.5e-13 50.8 0.9 2.6 2 1 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase ArsA_ATPase PF02374.15 AIM22205.1 - 4.3e-10 39.3 3.0 1.7e-09 37.3 2.1 2.1 2 0 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.11 AIM22205.1 - 3.7e-09 36.3 0.9 7.5e-09 35.2 0.9 1.5 1 1 0 1 1 1 1 ATPase MipZ CBP_BcsQ PF06564.12 AIM22205.1 - 1.3e-06 28.1 0.0 2.6e-06 27.1 0.0 1.7 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 AIM22205.1 - 2.3e-05 24.0 0.1 0.00076 19.0 0.1 2.4 2 1 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_24 PF13479.6 AIM22205.1 - 0.00045 20.0 0.0 0.00067 19.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_26 PF13500.6 AIM22205.1 - 0.0033 17.3 1.7 2 8.2 1.4 2.9 2 1 1 3 3 3 1 AAA domain CLP1_P PF16575.5 AIM22205.1 - 0.004 17.0 0.1 0.0081 16.0 0.1 1.5 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop VirC1 PF07015.11 AIM22205.1 - 0.01 15.1 0.2 0.02 14.2 0.2 1.4 1 0 0 1 1 1 0 VirC1 protein SRP54 PF00448.22 AIM22205.1 - 0.013 15.1 1.7 0.022 14.4 1.2 1.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF87 PF01935.17 AIM22205.1 - 0.075 13.1 0.3 0.23 11.5 0.3 1.9 1 1 0 1 1 1 0 Helicase HerA, central domain CobA_CobO_BtuR PF02572.15 AIM22205.1 - 0.21 11.8 0.6 0.6 10.4 0.6 1.7 1 1 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP AAA_25 PF13481.6 AIM22205.1 - 0.64 9.6 2.5 3 7.4 2.5 2.0 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AIM22205.1 - 0.9 9.2 2.5 1.6 8.4 2.5 1.3 1 0 0 1 1 1 0 AAA domain MinE PF03776.14 AIM22206.1 - 7e-24 83.6 0.0 8.2e-24 83.4 0.0 1.1 1 0 0 1 1 1 1 Septum formation topological specificity factor MinE DNA_pol_A_exo1 PF01612.20 AIM22207.1 - 4.8e-38 130.6 0.0 3.4e-37 127.8 0.0 2.0 2 0 0 2 2 2 1 3'-5' exonuclease HRDC PF00570.23 AIM22207.1 - 1.7e-15 56.8 0.1 3.7e-15 55.7 0.1 1.6 1 0 0 1 1 1 1 HRDC domain AMP-binding PF00501.28 AIM22208.1 - 8.4e-109 364.0 0.0 1.1e-108 363.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AIM22208.1 - 6.9e-19 68.6 1.6 1e-17 64.9 0.6 2.7 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.6 AIM22208.1 - 0.026 14.8 0.0 0.12 12.7 0.0 2.1 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain Pept_S41_N PF18294.1 AIM22208.1 - 0.11 12.5 0.0 24 5.0 0.0 2.4 2 0 0 2 2 2 0 Peptidase S41 N-terminal domain Slp PF03843.13 AIM22209.1 - 2.2e-46 157.0 0.0 2.8e-46 156.7 0.0 1.0 1 0 0 1 1 1 1 Outer membrane lipoprotein Slp family Peptidase_M22 PF00814.25 AIM22210.1 - 4.5e-31 108.5 0.0 6e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family LpxI_C PF06230.11 AIM22210.1 - 0.04 13.8 0.0 0.5 10.2 0.0 2.3 2 0 0 2 2 2 0 LpxI C-terminal domain Helicase_C_2 PF13307.6 AIM22211.1 - 2.7e-35 122.1 0.0 4.8e-35 121.2 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD PF00270.29 AIM22211.1 - 8.4e-08 32.2 0.5 0.00013 21.8 0.1 3.3 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.15 AIM22211.1 - 3.4e-06 27.2 0.1 6.9e-05 22.9 0.1 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD_2 PF06733.15 AIM22211.1 - 3.8e-05 23.4 0.0 7.2e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 DUF2075 PF09848.9 AIM22211.1 - 0.042 13.1 0.2 0.66 9.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) POTRA_2 PF08479.11 AIM22211.1 - 0.058 13.2 0.0 0.18 11.6 0.0 1.9 1 0 0 1 1 1 0 POTRA domain, ShlB-type UvrD-helicase PF00580.21 AIM22211.1 - 0.068 12.7 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain SH PF01445.17 AIM22211.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Viral small hydrophobic protein PSII PF00421.19 AIM22211.1 - 0.18 10.5 0.0 0.26 9.9 0.0 1.1 1 0 0 1 1 1 0 Photosystem II protein Ribonuc_L-PSP PF01042.21 AIM22212.1 - 2.3e-24 85.7 0.5 2.6e-24 85.5 0.5 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Multi_Drug_Res PF00893.19 AIM22213.1 - 1e-26 93.4 8.8 1.3e-26 93.1 8.8 1.1 1 0 0 1 1 1 1 Small Multidrug Resistance protein EamA PF00892.20 AIM22213.1 - 0.00096 19.3 12.1 0.0011 19.1 12.1 1.1 1 0 0 1 1 1 1 EamA-like transporter family UPF0060 PF02694.15 AIM22213.1 - 0.011 16.0 6.7 0.013 15.7 6.7 1.2 1 0 0 1 1 1 0 Uncharacterised BCR, YnfA/UPF0060 family TMEM234 PF10639.9 AIM22213.1 - 0.02 14.9 0.2 0.043 13.8 0.1 1.5 1 1 1 2 2 2 0 Putative transmembrane family 234 Multi_Drug_Res PF00893.19 AIM22214.1 - 8.8e-24 84.0 12.6 1.2e-23 83.5 12.6 1.1 1 0 0 1 1 1 1 Small Multidrug Resistance protein EamA PF00892.20 AIM22214.1 - 0.035 14.3 13.0 0.056 13.6 13.0 1.5 1 1 0 1 1 1 0 EamA-like transporter family TPT PF03151.16 AIM22214.1 - 0.038 13.4 4.6 0.046 13.1 4.6 1.2 1 0 0 1 1 1 0 Triose-phosphate Transporter family Aldolase PF01081.19 AIM22215.1 - 2.7e-88 294.5 0.6 3.1e-88 294.3 0.6 1.0 1 0 0 1 1 1 1 KDPG and KHG aldolase HMGL-like PF00682.19 AIM22215.1 - 0.00091 18.9 0.1 0.0012 18.4 0.1 1.2 1 0 0 1 1 1 1 HMGL-like IMPDH PF00478.25 AIM22215.1 - 0.14 11.1 0.1 0.15 11.0 0.1 1.1 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain G6PD_C PF02781.16 AIM22216.1 - 9.9e-118 392.5 0.0 1.3e-117 392.2 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 AIM22216.1 - 1.3e-59 201.8 0.0 4.4e-59 200.1 0.0 1.8 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain ThiW PF09512.10 AIM22216.1 - 0.14 12.3 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Thiamine-precursor transporter protein (ThiW) HTH_6 PF01418.17 AIM22217.1 - 6.5e-30 102.9 0.0 2.2e-29 101.3 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain, rpiR family SIS PF01380.22 AIM22217.1 - 4.9e-25 87.9 0.2 7.9e-25 87.2 0.2 1.3 1 0 0 1 1 1 1 SIS domain SIS_2 PF13580.6 AIM22217.1 - 1.1e-10 41.7 2.0 7.5e-07 29.3 0.1 2.5 1 1 1 2 2 2 2 SIS domain HTH_Tnp_ISL3 PF13542.6 AIM22217.1 - 0.0037 16.6 0.1 0.011 15.1 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_29 PF13551.6 AIM22217.1 - 0.018 15.0 0.0 0.05 13.6 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn helix LigT_PEase PF02834.16 AIM22217.1 - 0.026 14.7 0.0 0.17 12.1 0.0 2.2 2 0 0 2 2 2 0 LigT like Phosphoesterase HTH_24 PF13412.6 AIM22217.1 - 0.036 13.6 0.0 0.18 11.4 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 AIM22217.1 - 0.043 13.6 0.0 0.084 12.7 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Penicillinase_R PF03965.16 AIM22217.1 - 0.05 14.0 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 Penicillinase repressor MarR PF01047.22 AIM22217.1 - 0.07 13.1 0.0 0.66 10.0 0.0 2.3 2 0 0 2 2 2 0 MarR family MarR_2 PF12802.7 AIM22217.1 - 0.22 11.4 1.1 1.3 9.0 0.0 2.7 3 1 0 3 3 3 0 MarR family DUF3640 PF12342.8 AIM22217.1 - 0.23 11.2 0.5 0.51 10.1 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3640) PK PF00224.21 AIM22218.1 - 1e-132 442.3 5.0 1.5e-132 441.7 5.0 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 AIM22218.1 - 1.7e-28 99.2 0.2 4.9e-28 97.7 0.2 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain Peptidase_M20 PF01546.28 AIM22218.1 - 0.14 11.9 0.1 1.2 8.8 0.0 2.0 2 0 0 2 2 2 0 Peptidase family M20/M25/M40 LRR_8 PF13855.6 AIM22219.1 - 3.1e-46 155.0 41.9 1.4e-10 40.8 1.5 5.8 1 1 6 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 AIM22219.1 - 2.2e-30 104.2 17.3 7.3e-07 29.4 0.1 6.0 3 1 3 7 7 7 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 AIM22219.1 - 8.6e-14 50.0 15.4 0.34 11.6 0.2 9.5 10 0 0 10 10 10 5 Leucine Rich Repeat LRR_9 PF14580.6 AIM22219.1 - 7.2e-09 35.4 5.0 0.0047 16.4 0.5 3.2 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 AIM22219.1 - 7.7e-07 28.7 18.5 0.79 9.9 0.1 7.3 8 0 0 8 8 8 4 Leucine Rich repeat DUF2385 PF09539.10 AIM22219.1 - 0.087 13.4 0.6 1.1e+02 3.4 0.0 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF2385) LRR_5 PF13306.6 AIM22219.1 - 0.24 11.3 0.0 1.1 9.2 0.0 1.9 2 0 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) Lip_A_acyltrans PF03279.13 AIM22220.1 - 3e-93 312.2 0.0 3.4e-93 312.0 0.0 1.0 1 0 0 1 1 1 1 Bacterial lipid A biosynthesis acyltransferase Peptidase_M23 PF01551.22 AIM22221.1 - 1.3e-34 118.2 0.5 2.7e-34 117.2 0.2 1.7 2 0 0 2 2 2 1 Peptidase family M23 OapA_N PF08525.11 AIM22221.1 - 1.2e-08 34.7 0.1 2.1e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 Opacity-associated protein A N-terminal motif OapA PF04225.12 AIM22221.1 - 3e-07 30.4 0.7 1.5e-05 25.0 0.1 2.7 2 1 0 2 2 2 1 Opacity-associated protein A LysM-like domain LysM PF01476.20 AIM22221.1 - 9.6e-06 25.6 1.4 1.9e-05 24.6 0.2 2.2 2 0 0 2 2 2 1 LysM domain Biotin_lipoyl_2 PF13533.6 AIM22221.1 - 0.059 13.2 0.1 0.21 11.4 0.1 2.1 2 0 0 2 2 2 0 Biotin-lipoyl like 2C_adapt PF08793.10 AIM22221.1 - 0.25 11.5 1.1 1.7 8.9 0.2 2.6 3 0 0 3 3 3 0 2-cysteine adaptor domain ZnuA PF01297.17 AIM22222.1 - 1.4e-55 188.5 0.0 1.6e-55 188.3 0.0 1.0 1 0 0 1 1 1 1 Zinc-uptake complex component A periplasmic ABC_tran PF00005.27 AIM22223.1 - 5.7e-30 104.6 0.0 8.9e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIM22223.1 - 1.3e-07 31.8 0.7 0.0047 16.8 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AIM22223.1 - 0.0022 18.4 0.3 0.0038 17.6 0.3 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AIM22223.1 - 0.0032 17.2 0.1 0.0067 16.1 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AIM22223.1 - 0.0047 16.9 0.1 0.011 15.7 0.1 1.6 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 AIM22223.1 - 0.0056 16.1 0.3 0.97 8.8 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 AIM22223.1 - 0.0063 16.1 0.3 1.5 8.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 AIM22223.1 - 0.02 14.8 0.1 0.039 13.9 0.1 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_22 PF13401.6 AIM22223.1 - 0.022 15.0 0.3 0.072 13.4 0.3 1.9 1 1 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 AIM22223.1 - 0.029 13.2 0.2 0.3 9.8 0.0 2.3 2 1 0 2 2 2 0 Predicted ATPase of the ABC class NB-ARC PF00931.22 AIM22223.1 - 0.044 12.9 0.2 0.27 10.4 0.1 2.2 1 1 0 1 1 1 0 NB-ARC domain AAA_23 PF13476.6 AIM22223.1 - 0.061 13.8 0.0 0.091 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain MutS_V PF00488.21 AIM22223.1 - 0.072 13.1 0.1 12 5.9 0.0 2.1 2 0 0 2 2 2 0 MutS domain V SbcCD_C PF13558.6 AIM22223.1 - 0.12 12.6 0.0 2.6 8.4 0.0 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 AIM22223.1 - 0.13 12.4 0.0 0.21 11.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_PrkA PF08298.11 AIM22223.1 - 0.15 11.0 0.1 0.21 10.4 0.1 1.2 1 0 0 1 1 1 0 PrkA AAA domain AAA PF00004.29 AIM22223.1 - 0.17 12.3 0.1 0.49 10.8 0.1 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC-3 PF00950.17 AIM22224.1 - 1e-84 284.1 25.1 1.2e-84 283.9 25.1 1.0 1 0 0 1 1 1 1 ABC 3 transport family FecCD PF01032.18 AIM22224.1 - 1.8e-08 33.8 25.8 2.4e-08 33.4 25.8 1.2 1 0 0 1 1 1 1 FecCD transport family RuvB_N PF05496.12 AIM22225.1 - 6.6e-83 276.2 0.0 9e-83 275.7 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_4 PF17864.1 AIM22225.1 - 1.9e-31 107.6 0.4 3.3e-31 106.8 0.4 1.4 1 0 0 1 1 1 1 RuvB AAA lid domain RuvB_C PF05491.13 AIM22225.1 - 1.8e-27 95.0 0.0 3.1e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 RuvB C-terminal winged helix domain AAA PF00004.29 AIM22225.1 - 2.1e-19 70.3 0.0 5.7e-19 68.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AIM22225.1 - 2.6e-08 34.0 0.0 1.1e-05 25.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 AIM22225.1 - 3.1e-05 23.4 0.2 0.00098 18.4 0.0 2.7 3 0 0 3 3 3 1 TIP49 P-loop domain AAA_22 PF13401.6 AIM22225.1 - 5.5e-05 23.5 0.1 0.027 14.8 0.0 2.7 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.21 AIM22225.1 - 0.0001 21.8 0.2 0.04 13.3 0.0 2.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 AIM22225.1 - 0.0002 21.2 0.0 0.15 12.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 AIM22225.1 - 0.00048 19.9 0.0 0.87 9.3 0.0 2.3 1 1 1 2 2 2 2 Sigma-54 interaction domain Rad17 PF03215.15 AIM22225.1 - 0.00085 19.3 0.0 0.0013 18.7 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 AIM22225.1 - 0.001 19.5 0.2 0.081 13.3 0.0 2.9 2 1 0 3 3 3 1 AAA ATPase domain AAA_14 PF13173.6 AIM22225.1 - 0.0043 17.1 0.0 0.0091 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AIM22225.1 - 0.0067 17.0 0.0 0.019 15.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain NTPase_1 PF03266.15 AIM22225.1 - 0.02 14.8 0.2 0.15 11.9 0.0 2.1 1 1 1 2 2 2 0 NTPase Bac_DnaA PF00308.18 AIM22225.1 - 0.025 14.4 0.0 0.18 11.6 0.0 2.0 2 0 0 2 2 2 0 Bacterial dnaA protein RNA_helicase PF00910.22 AIM22225.1 - 0.03 14.7 0.0 0.056 13.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 AIM22225.1 - 0.037 14.0 0.0 0.066 13.2 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 AIM22225.1 - 0.046 13.4 0.0 0.12 12.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 AIM22225.1 - 0.051 12.6 0.0 0.09 11.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_17 PF13207.6 AIM22225.1 - 0.059 13.8 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 AIM22225.1 - 0.074 12.8 0.1 0.36 10.5 0.1 2.1 1 1 0 1 1 1 0 IstB-like ATP binding protein NB-ARC PF00931.22 AIM22225.1 - 0.08 12.1 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain TniB PF05621.11 AIM22225.1 - 0.092 12.2 0.1 1.8 7.9 0.0 2.2 1 1 1 2 2 2 0 Bacterial TniB protein DUF815 PF05673.13 AIM22225.1 - 0.11 11.7 0.0 2.8 7.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MCM PF00493.23 AIM22225.1 - 0.12 11.5 0.0 7.8 5.5 0.0 2.2 1 1 1 2 2 2 0 MCM P-loop domain AAA_19 PF13245.6 AIM22225.1 - 0.13 12.6 0.5 2.1 8.7 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_28 PF13521.6 AIM22225.1 - 0.14 12.4 0.2 0.35 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 AIM22225.1 - 0.21 12.1 0.0 0.36 11.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter RuvA_N PF01330.21 AIM22226.1 - 1.8e-21 76.0 0.0 1.2e-20 73.3 0.0 2.2 2 0 0 2 2 2 1 RuvA N terminal domain HHH_5 PF14520.6 AIM22226.1 - 1.8e-17 63.7 0.4 4.4e-17 62.4 0.2 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain RuvA_C PF07499.13 AIM22226.1 - 7.1e-16 58.4 0.6 7.1e-16 58.4 0.6 2.0 2 0 0 2 2 2 1 RuvA, C-terminal domain HHH PF00633.23 AIM22226.1 - 1.2e-09 37.5 0.7 0.002 17.9 0.2 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix motif IMS_HHH PF11798.8 AIM22226.1 - 0.00046 20.3 0.1 0.064 13.6 0.0 2.6 2 0 0 2 2 2 1 IMS family HHH motif HHH_2 PF12826.7 AIM22226.1 - 0.0016 18.5 0.0 0.41 10.8 0.0 2.6 2 1 1 3 3 3 1 Helix-hairpin-helix motif HHH_3 PF12836.7 AIM22226.1 - 0.0024 18.1 0.0 2.5 8.4 0.0 2.4 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_8 PF14716.6 AIM22226.1 - 0.0027 18.1 0.3 0.45 10.9 0.0 2.7 3 0 0 3 3 3 1 Helix-hairpin-helix domain Transposase_20 PF02371.16 AIM22226.1 - 0.011 16.0 0.0 0.72 10.2 0.0 2.3 2 0 0 2 2 2 0 Transposase IS116/IS110/IS902 family 5_3_exonuc PF01367.20 AIM22226.1 - 0.03 14.9 0.2 2.6 8.7 0.0 2.3 1 1 1 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Cdd1 PF11731.8 AIM22226.1 - 0.16 12.2 0.0 0.98 9.7 0.0 2.2 2 0 0 2 2 2 0 Pathogenicity locus RuvC PF02075.17 AIM22227.1 - 3.9e-66 221.5 1.1 4.6e-66 221.3 1.1 1.0 1 0 0 1 1 1 1 Crossover junction endodeoxyribonuclease RuvC DUF3882 PF07066.11 AIM22227.1 - 0.011 15.8 0.0 0.037 14.1 0.0 1.8 1 1 0 1 1 1 0 Lactococcus phage M3 protein NeuB PF03102.14 AIM22227.1 - 0.021 14.3 0.1 0.027 13.9 0.1 1.1 1 0 0 1 1 1 0 NeuB family Transcrip_reg PF01709.20 AIM22228.1 - 7.1e-95 317.0 0.0 7.9e-95 316.8 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator NUDIX PF00293.28 AIM22229.1 - 1.7e-16 60.4 1.0 2e-16 60.2 1.0 1.1 1 0 0 1 1 1 1 NUDIX domain tRNA-synt_2 PF00152.20 AIM22230.1 - 2.2e-107 358.8 0.0 2.6e-107 358.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) GAD PF02938.14 AIM22230.1 - 5.3e-31 106.7 0.1 1.2e-30 105.6 0.1 1.6 1 0 0 1 1 1 1 GAD domain tRNA_anti-codon PF01336.25 AIM22230.1 - 1.7e-15 56.8 1.2 3.7e-15 55.7 0.1 2.2 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 AIM22230.1 - 0.00062 19.3 0.1 1 8.8 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.25 AIM22230.1 - 0.1 12.6 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) Zn-ribbon_8 PF09723.10 AIM22231.1 - 1.4e-17 63.5 0.3 1.7e-17 63.2 0.3 1.1 1 0 0 1 1 1 1 Zinc ribbon domain zf-TFIIB PF13453.6 AIM22231.1 - 0.0064 15.8 0.8 0.012 14.9 0.8 1.5 1 1 0 1 1 1 1 Transcription factor zinc-finger DZR PF12773.7 AIM22231.1 - 0.0078 16.2 0.6 0.011 15.8 0.6 1.2 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.19 AIM22231.1 - 0.0081 16.2 0.1 0.0094 16.0 0.1 1.0 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-LITAF-like PF10601.9 AIM22231.1 - 0.012 15.9 0.2 0.57 10.5 0.0 2.1 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain NOB1_Zn_bind PF08772.11 AIM22231.1 - 0.013 15.6 0.1 0.018 15.2 0.1 1.3 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zf-ribbon_3 PF13248.6 AIM22231.1 - 0.023 14.1 0.6 0.52 9.8 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Ribosomal_L32p PF01783.23 AIM22231.1 - 0.14 12.4 0.0 0.21 11.9 0.0 1.4 1 1 0 1 1 1 0 Ribosomal L32p protein family zinc-ribbons_6 PF07191.12 AIM22231.1 - 0.2 11.6 2.2 1.1 9.2 2.2 1.9 1 1 0 1 1 1 0 zinc-ribbons Isochorismatase PF00857.20 AIM22232.1 - 1e-38 133.2 0.0 1.2e-38 133.1 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family DUF72 PF01904.18 AIM22233.1 - 3.3e-49 167.9 0.6 4.2e-49 167.6 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF72 MAPEG PF01124.18 AIM22234.1 - 3.5e-25 88.4 8.8 4e-25 88.2 8.8 1.0 1 0 0 1 1 1 1 MAPEG family Methyltransf_25 PF13649.6 AIM22235.1 - 2.3e-15 57.1 0.0 5.9e-15 55.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 AIM22235.1 - 6e-14 52.5 0.0 1.2e-13 51.5 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AIM22235.1 - 2e-10 40.7 0.0 6e-10 39.1 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIM22235.1 - 1.3e-09 38.7 0.0 2.3e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 AIM22235.1 - 2e-07 30.5 0.0 2.9e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Ubie_methyltran PF01209.18 AIM22235.1 - 5.2e-07 29.2 0.0 9.7e-07 28.3 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 AIM22235.1 - 6.8e-07 29.3 0.0 1.1e-06 28.6 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AIM22235.1 - 0.00013 21.6 0.0 0.00019 21.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CheR PF01739.18 AIM22235.1 - 0.00023 20.7 0.0 0.38 10.2 0.0 2.2 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain PCMT PF01135.19 AIM22235.1 - 0.0031 17.3 0.0 0.0049 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_8 PF05148.15 AIM22235.1 - 0.0048 16.8 0.1 0.032 14.1 0.1 2.0 1 1 0 1 1 1 1 Hypothetical methyltransferase PrmA PF06325.13 AIM22235.1 - 0.0073 15.7 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Rsm22 PF09243.10 AIM22235.1 - 0.015 14.5 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 MetW PF07021.12 AIM22235.1 - 0.039 13.5 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_18 PF12847.7 AIM22235.1 - 0.051 13.5 0.0 0.082 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 AIM22235.1 - 0.055 13.6 0.1 0.16 12.1 0.1 1.8 1 1 0 1 1 1 0 FtsJ-like methyltransferase UPF0020 PF01170.18 AIM22235.1 - 0.085 12.5 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_9 PF08003.11 AIM22236.1 - 5.2e-165 548.0 0.0 5.9e-165 547.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.6 AIM22236.1 - 4.8e-09 36.3 0.0 1.3e-08 34.8 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 AIM22236.1 - 1.8e-07 31.1 0.0 3.4e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AIM22236.1 - 1.2e-06 29.1 0.0 7.6e-06 26.6 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 AIM22236.1 - 7.2e-06 26.6 0.0 3.9e-05 24.2 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIM22236.1 - 8.6e-05 23.2 0.0 0.00022 21.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 AIM22236.1 - 0.00023 20.5 0.0 0.00034 20.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 AIM22236.1 - 0.13 12.0 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FKBP_N PF01346.18 AIM22237.1 - 6.8e-17 62.2 0.5 6.8e-17 62.2 0.5 6.2 2 1 1 3 3 3 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase FKBP_C PF00254.28 AIM22237.1 - 9.9e-08 32.2 0.0 2.5e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase MCPVI PF02993.14 AIM22238.1 - 0.032 14.1 2.1 0.038 13.8 2.1 1.1 1 0 0 1 1 1 0 Minor capsid protein VI PAXX PF15384.6 AIM22238.1 - 0.057 13.1 1.4 0.066 12.9 1.4 1.1 1 0 0 1 1 1 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 Histone PF00125.24 AIM22238.1 - 0.19 12.1 2.5 0.22 11.9 2.5 1.1 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 AIP3 PF03915.13 AIM22239.1 - 0.033 13.3 0.1 0.036 13.2 0.1 1.0 1 0 0 1 1 1 0 Actin interacting protein 3 LPAM_1 PF08139.12 AIM22239.1 - 0.9 10.2 4.2 1.9 9.2 4.2 1.5 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site CutC PF03932.14 AIM22240.1 - 6.1e-73 244.6 0.0 7.5e-73 244.3 0.0 1.1 1 0 0 1 1 1 1 CutC family Aminotran_1_2 PF00155.21 AIM22241.1 - 4.7e-33 114.8 0.0 5.3e-33 114.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II YecM PF06185.12 AIM22242.1 - 5.1e-75 251.1 0.0 5.8e-75 250.9 0.0 1.0 1 0 0 1 1 1 1 YecM protein tRNA-synt_1d PF00750.19 AIM22243.1 - 1.9e-164 546.7 0.4 2.3e-164 546.4 0.4 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 AIM22243.1 - 3.4e-35 120.8 0.1 8.4e-35 119.5 0.1 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 AIM22243.1 - 6.2e-22 78.0 0.0 1.9e-21 76.4 0.0 1.8 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1 PF00133.22 AIM22243.1 - 0.0038 15.5 0.0 0.0058 14.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 AIM22243.1 - 0.0055 15.5 0.1 0.011 14.6 0.1 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 AIM22243.1 - 0.017 14.5 0.1 0.03 13.7 0.1 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Polysacc_deac_3 PF15421.6 AIM22243.1 - 0.045 12.3 0.0 0.079 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative polysaccharide deacetylase MurJ PF03023.14 AIM22244.1 - 3.2e-156 520.4 30.8 3.9e-156 520.2 30.8 1.1 1 0 0 1 1 1 1 Lipid II flippase MurJ Polysacc_synt_C PF14667.6 AIM22244.1 - 2.6e-10 40.5 17.8 2.6e-10 40.5 17.8 4.0 3 2 0 3 3 3 2 Polysaccharide biosynthesis C-terminal domain GFO_IDH_MocA PF01408.22 AIM22245.1 - 3.1e-24 86.1 0.0 4.7e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 AIM22245.1 - 0.0026 18.3 0.0 0.0084 16.7 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 AIM22245.1 - 0.023 14.1 0.0 0.059 12.7 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF480 PF04337.12 AIM22246.1 - 8.3e-64 214.2 0.7 8.3e-64 214.2 0.7 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF480 Acetyltransf_3 PF13302.7 AIM22247.1 - 8.3e-18 65.4 0.1 1e-17 65.1 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AIM22247.1 - 2.8e-07 30.8 0.0 3.5e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AIM22247.1 - 5e-06 26.7 0.0 6.6e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 AIM22247.1 - 1.9e-05 24.4 0.0 3e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AIM22247.1 - 0.01 15.8 0.0 0.024 14.6 0.0 1.5 2 0 0 2 2 2 0 FR47-like protein MFS_1 PF07690.16 AIM22248.1 - 2.1e-30 105.9 48.5 2.1e-21 76.3 27.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AIM22248.1 - 0.0068 15.3 4.7 0.0068 15.3 4.7 2.9 3 1 0 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.7 AIM22248.1 - 0.25 10.2 17.6 0.0088 14.9 6.7 2.4 2 1 0 2 2 2 0 MFS_1 like family Glutaredoxin2_C PF04399.13 AIM22250.1 - 3.3e-48 162.8 0.0 4e-48 162.5 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain GST_N_3 PF13417.6 AIM22250.1 - 6.8e-12 45.6 0.0 1.4e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AIM22250.1 - 4.4e-07 30.1 0.0 1.8e-06 28.1 0.0 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 AIM22250.1 - 0.023 14.9 0.0 0.056 13.7 0.0 1.7 1 0 0 1 1 1 0 Glutaredoxin ABC1 PF03109.16 AIM22251.1 - 1.2e-33 115.8 0.0 1.9e-33 115.2 0.0 1.3 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 AIM22251.1 - 3.9e-07 30.2 4.7 3.9e-07 30.2 4.7 3.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family DUF1439 PF07273.12 AIM22252.1 - 5.5e-58 195.1 2.0 6.3e-58 194.9 2.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1439) LPAM_1 PF08139.12 AIM22252.1 - 6.3 7.5 5.6 30 5.4 5.6 2.1 1 1 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site YebF PF13995.6 AIM22253.1 - 8.1e-37 125.1 0.0 1.1e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 YebF-like protein PepSY PF03413.19 AIM22253.1 - 0.0043 17.6 0.0 0.0066 17.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase propeptide and YPEB domain ASCH PF04266.14 AIM22254.1 - 6.1e-16 58.9 0.0 7.2e-16 58.7 0.0 1.0 1 0 0 1 1 1 1 ASCH domain YebG PF07130.12 AIM22255.1 - 5.8e-35 119.0 0.3 8e-35 118.5 0.3 1.2 1 0 0 1 1 1 1 YebG protein Sdh5 PF03937.16 AIM22255.1 - 0.09 12.7 1.3 2.7 8.0 0.2 2.1 1 1 1 2 2 2 0 Flavinator of succinate dehydrogenase DEAD PF00270.29 AIM22256.1 - 6.2e-46 156.4 0.1 2.5e-45 154.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AIM22256.1 - 5.5e-29 100.8 0.0 2.4e-27 95.5 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DbpA PF03880.15 AIM22256.1 - 5e-23 80.9 0.0 1e-22 79.9 0.0 1.6 1 0 0 1 1 1 1 DbpA RNA binding domain ResIII PF04851.15 AIM22256.1 - 1.1e-07 32.0 0.0 1.7e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 AIM22256.1 - 0.0022 18.3 0.0 0.21 11.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain CMS1 PF14617.6 AIM22256.1 - 0.0024 17.2 0.1 0.0081 15.5 0.0 1.8 2 1 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit PucR PF07905.11 AIM22256.1 - 0.026 14.8 0.1 3.8 7.8 0.0 2.5 1 1 1 2 2 2 0 Purine catabolism regulatory protein-like family Helicase_RecD PF05127.14 AIM22256.1 - 0.11 12.4 0.0 0.95 9.3 0.0 2.2 2 0 0 2 2 2 0 Helicase CSD PF00313.22 AIM22257.1 - 8e-32 108.9 0.6 8.7e-32 108.8 0.6 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 AIM22257.1 - 0.0018 17.9 0.4 0.0022 17.6 0.4 1.4 1 1 0 1 1 1 1 Ribonuclease B OB domain ATP-grasp PF02222.22 AIM22258.1 - 3.8e-56 189.3 0.0 6.3e-56 188.6 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 AIM22258.1 - 1e-07 31.7 0.0 2.5e-07 30.4 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 AIM22258.1 - 6.2e-06 26.3 0.0 1.4e-05 25.2 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 AIM22258.1 - 8.4e-06 25.4 0.0 1.7e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Epimerase PF01370.21 AIM22258.1 - 0.00021 20.9 0.0 0.00033 20.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 AIM22258.1 - 0.00086 18.7 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RimK PF08443.11 AIM22258.1 - 0.011 15.3 0.0 0.084 12.5 0.0 2.2 1 1 0 1 1 1 0 RimK-like ATP-grasp domain LAL_C2 PF18603.1 AIM22258.1 - 0.027 14.6 0.8 0.027 14.6 0.8 1.9 2 0 0 2 2 2 0 L-amino acid ligase C-terminal domain 2 ATP-grasp_4 PF13535.6 AIM22258.1 - 0.056 13.0 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain MccV PF17508.2 AIM22258.1 - 0.093 13.3 0.0 0.22 12.1 0.0 1.6 1 0 0 1 1 1 0 Microcin V bacteriocin 3HCDH_N PF02737.18 AIM22258.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 AIM22258.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.5 1 1 0 1 1 1 0 RmlD substrate binding domain UPF0181 PF03701.14 AIM22259.1 - 1e-21 76.3 6.8 1e-21 76.3 6.8 1.8 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0181) VWA PF00092.28 AIM22259.1 - 0.0027 18.0 0.0 0.0029 17.9 0.0 1.0 1 0 0 1 1 1 1 von Willebrand factor type A domain Chal_sti_synt_N PF00195.19 AIM22259.1 - 0.028 13.9 0.0 0.028 13.9 0.0 1.0 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain NBD_C PF17042.5 AIM22259.1 - 0.37 11.3 2.5 0.4 11.2 2.5 1.1 1 0 0 1 1 1 0 Nucleotide-binding C-terminal domain Glycos_transf_2 PF00535.26 AIM22260.1 - 5.2e-32 111.0 0.0 8.9e-32 110.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AIM22260.1 - 2.3e-14 53.9 1.0 7.3e-14 52.2 1.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 AIM22260.1 - 3.3e-09 36.6 0.0 4.9e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AIM22260.1 - 5.7e-05 23.5 0.0 0.00016 22.1 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 DUF3100 PF11299.8 AIM22260.1 - 0.21 11.0 0.0 0.41 10.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3100) Chorismate_bind PF00425.18 AIM22261.1 - 3e-95 318.7 0.0 3.9e-95 318.3 0.0 1.1 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 AIM22261.1 - 3.2e-24 85.7 0.0 7.4e-24 84.6 0.0 1.6 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region NUDIX PF00293.28 AIM22262.1 - 4.4e-13 49.4 0.0 6.6e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain SDH_alpha PF03313.15 AIM22263.1 - 6.1e-96 321.1 4.5 7.8e-96 320.7 4.5 1.1 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 AIM22263.1 - 1.6e-56 191.0 0.0 3e-56 190.1 0.0 1.5 1 0 0 1 1 1 1 Serine dehydratase beta chain EAL PF00563.20 AIM22264.1 - 5.1e-61 206.2 0.0 9.5e-61 205.3 0.0 1.4 1 0 0 1 1 1 1 EAL domain CSS-motif PF12792.7 AIM22264.1 - 2.4e-25 89.3 0.4 4.2e-25 88.5 0.4 1.3 1 0 0 1 1 1 1 CSS motif domain associated with EAL TerC PF03741.16 AIM22265.1 - 5.9e-48 162.9 14.5 9.1e-48 162.3 14.5 1.3 1 0 0 1 1 1 1 Integral membrane protein TerC family CorC_HlyC PF03471.17 AIM22265.1 - 2.3e-17 62.8 0.4 6.8e-17 61.3 0.0 2.0 2 0 0 2 2 2 1 Transporter associated domain CBS PF00571.28 AIM22265.1 - 2.6e-12 47.0 2.0 2.5e-06 27.9 0.2 3.5 3 0 0 3 3 3 2 CBS domain DUF475 PF04332.15 AIM22265.1 - 0.015 15.1 9.0 0.14 11.9 8.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF475) TssN PF17555.2 AIM22265.1 - 7.1 5.9 8.1 3.8 6.8 2.0 2.1 2 0 0 2 2 2 0 Type VI secretion system, TssN PTSIIB_sorb PF03830.15 AIM22266.1 - 3.1e-56 189.7 1.0 4.7e-56 189.1 1.0 1.3 1 0 0 1 1 1 1 PTS system sorbose subfamily IIB component EIIA-man PF03610.16 AIM22266.1 - 1.2e-33 115.8 0.1 2.4e-33 114.8 0.1 1.5 1 0 0 1 1 1 1 PTS system fructose IIA component EII-Sor PF03609.14 AIM22267.1 - 6.5e-74 248.2 41.7 7.5e-74 248.1 41.7 1.0 1 0 0 1 1 1 1 PTS system sorbose-specific iic component Poxvirus_B22R_C PF13168.6 AIM22267.1 - 9 5.7 8.7 23 4.4 3.2 2.3 2 0 0 2 2 2 0 Poxvirus B22R protein C-terminal EIID-AGA PF03613.14 AIM22268.1 - 3.3e-112 374.0 1.2 3.7e-112 373.8 1.2 1.0 1 0 0 1 1 1 1 PTS system mannose/fructose/sorbose family IID component DUF986 PF06173.12 AIM22269.1 - 8.3e-65 217.4 7.6 9.3e-65 217.2 7.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF986) UL20 PF17582.2 AIM22269.1 - 0.034 13.4 0.1 0.045 13.0 0.1 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL20 Mntp PF02659.15 AIM22270.1 - 1.9e-55 186.8 17.6 2.8e-55 186.2 10.3 2.0 2 0 0 2 2 2 2 Putative manganese efflux pump DUF2953 PF11167.8 AIM22270.1 - 0.0047 17.0 2.4 1.4 9.1 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF2953) Colicin PF01024.19 AIM22270.1 - 0.15 12.0 1.2 0.24 11.3 1.2 1.4 1 0 0 1 1 1 0 Colicin pore forming domain Abhydrolase_9_N PF15420.6 AIM22270.1 - 0.28 11.2 4.9 1.7 8.6 4.9 2.0 1 1 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus RseC_MucC PF04246.12 AIM22270.1 - 3 7.8 7.3 5.7 6.9 0.0 2.8 2 1 1 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Methyltransf_31 PF13847.6 AIM22271.1 - 3.3e-14 52.9 0.0 7.7e-14 51.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AIM22271.1 - 4e-13 49.9 0.0 1.1e-12 48.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AIM22271.1 - 4.6e-13 49.6 0.5 3.2e-12 47.0 0.5 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIM22271.1 - 5.2e-05 23.9 0.0 0.0005 20.8 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 AIM22271.1 - 6.2e-05 22.5 0.0 0.00012 21.5 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 AIM22271.1 - 0.00024 21.0 0.0 0.0037 17.1 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 AIM22271.1 - 0.00032 20.7 0.0 0.00051 20.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 AIM22271.1 - 0.00088 18.8 0.0 2.7 7.4 0.0 3.1 3 0 0 3 3 3 1 Putative methyltransferase PCMT PF01135.19 AIM22271.1 - 0.0013 18.6 0.2 0.0077 16.0 0.0 2.2 3 0 0 3 3 3 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 AIM22271.1 - 0.0035 16.9 0.3 0.0091 15.6 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_29 PF03141.16 AIM22271.1 - 0.0075 14.9 0.1 0.011 14.3 0.1 1.4 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase zf-Mss51 PF13824.6 AIM22271.1 - 0.0092 16.1 1.6 0.02 15.0 1.6 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 PrmA PF06325.13 AIM22271.1 - 0.048 13.0 0.1 0.086 12.2 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) zinc-ribbon_6 PF10005.9 AIM22271.1 - 0.078 13.7 0.4 0.22 12.2 0.2 1.9 2 0 0 2 2 2 0 zinc-ribbon domain Methyltransf_24 PF13578.6 AIM22271.1 - 0.18 12.8 0.3 7.5 7.6 0.0 3.2 3 2 1 4 4 4 0 Methyltransferase domain Cu-oxidase_4 PF02578.15 AIM22272.1 - 7.6e-43 146.8 0.0 9.7e-43 146.4 0.0 1.1 1 0 0 1 1 1 1 Multi-copper polyphenol oxidoreductase laccase CSD PF00313.22 AIM22273.1 - 1.7e-33 114.2 1.6 1.9e-33 114.1 1.6 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 AIM22273.1 - 0.0012 18.5 0.4 0.0015 18.1 0.4 1.4 1 1 0 1 1 1 1 Ribonuclease B OB domain DUF2527 PF10736.9 AIM22274.1 - 3.9e-29 100.2 5.6 4.2e-29 100.1 5.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2627) Lactamase_B_2 PF12706.7 AIM22275.1 - 7.1e-46 156.3 0.1 1.4e-45 155.3 0.1 1.5 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 AIM22275.1 - 2.5e-21 76.3 0.0 3.1e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 AIM22275.1 - 2.1e-05 24.6 0.1 0.00077 19.5 0.0 2.7 2 2 0 2 2 2 1 Metallo-beta-lactamase superfamily AA_permease PF00324.21 AIM22277.1 - 9.3e-119 397.1 46.9 1e-118 397.0 46.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 AIM22277.1 - 2e-39 135.6 51.1 2.5e-39 135.3 51.1 1.0 1 0 0 1 1 1 1 Amino acid permease Thioesterase PF00975.20 AIM22277.1 - 0.15 12.2 0.1 0.26 11.4 0.1 1.3 1 0 0 1 1 1 0 Thioesterase domain DUF4060 PF13269.6 AIM22278.1 - 2.2e-33 114.1 0.2 2.5e-33 114.0 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4060) DUF2591 PF10765.9 AIM22279.1 - 1.6e-13 50.9 0.0 1.8e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2591) Glyoxalase PF00903.25 AIM22280.1 - 3.2e-11 43.5 0.0 4.8e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 AIM22280.1 - 2.6e-08 34.6 0.1 3.2e-08 34.3 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 AIM22280.1 - 0.0025 17.9 0.2 0.04 14.0 0.1 2.0 1 1 1 2 2 2 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 AIM22280.1 - 0.0082 16.4 0.0 0.04 14.2 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 AIM22280.1 - 0.14 12.1 0.0 1.2 9.1 0.0 2.0 1 1 0 1 1 1 0 Glyoxalase-like domain YebO PF13974.6 AIM22281.1 - 3.2e-27 94.4 0.0 4e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 YebO-like protein DUF2568 PF10823.8 AIM22281.1 - 0.0026 18.0 0.3 0.003 17.8 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2568) DUF4381 PF14316.6 AIM22281.1 - 0.022 15.0 3.3 0.028 14.7 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF1003 PF06210.11 AIM22281.1 - 0.027 14.5 0.2 0.032 14.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) MgrB PF13998.6 AIM22282.1 - 1.4e-15 56.9 0.2 1.6e-15 56.6 0.2 1.1 1 0 0 1 1 1 1 MgrB protein YobH PF13996.6 AIM22283.1 - 1.2e-26 92.6 0.5 1.3e-26 92.4 0.5 1.0 1 0 0 1 1 1 1 YobH-like protein DUF2766 PF10964.8 AIM22284.1 - 2e-46 155.8 1.0 2.2e-46 155.7 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2766) YccJ PF13993.6 AIM22285.1 - 2.2e-36 124.0 4.3 2.4e-36 123.9 4.3 1.0 1 0 0 1 1 1 1 YccJ-like protein HTH_18 PF12833.7 AIM22286.1 - 4.4e-22 78.1 0.2 5.9e-22 77.7 0.2 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AIM22286.1 - 1.1e-14 54.1 0.5 2.1e-08 34.1 0.3 2.2 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family DUF1475 PF07343.11 AIM22286.1 - 0.19 11.5 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1475) DUF1304 PF06993.12 AIM22287.1 - 1.3e-39 134.6 8.3 1.5e-39 134.4 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1304) Pirin PF02678.16 AIM22288.1 - 4.2e-30 103.9 0.1 6.5e-30 103.3 0.1 1.3 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 AIM22288.1 - 4.5e-20 71.9 0.0 2.3e-19 69.7 0.0 1.9 2 0 0 2 2 2 1 Pirin C-terminal cupin domain DUF4006 PF13179.6 AIM22289.1 - 0.13 12.2 2.1 0.16 11.9 2.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF4006) TarH PF02203.15 AIM22289.1 - 0.21 11.5 0.0 0.21 11.5 0.0 1.0 1 0 0 1 1 1 0 Tar ligand binding domain homologue PGF-CTERM PF18204.1 AIM22289.1 - 5.4 7.1 7.3 0.74 9.9 3.5 1.5 2 0 0 2 2 2 0 PGF-CTERM motif LysM PF01476.20 AIM22291.1 - 2e-14 53.4 0.0 3.8e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 LysM domain BON PF04972.17 AIM22291.1 - 5.6e-11 42.6 5.0 7.7e-11 42.1 5.0 1.2 1 0 0 1 1 1 1 BON domain HMA PF00403.26 AIM22291.1 - 0.0018 18.7 1.7 0.0078 16.6 1.4 2.1 1 1 1 2 2 2 1 Heavy-metal-associated domain DUF1482 PF07358.11 AIM22292.1 - 6.2e-27 93.3 0.5 6.9e-27 93.1 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1482) YmgB PF10798.8 AIM22293.1 - 3.5e-07 29.9 0.1 4.7e-07 29.5 0.1 1.1 1 0 0 1 1 1 1 Biofilm development protein YmgB/AriR Porin_1 PF00267.21 AIM22294.1 - 3.2e-141 470.7 30.7 3.6e-141 470.5 30.7 1.0 1 0 0 1 1 1 1 Gram-negative porin OMP_b-brl PF13505.6 AIM22294.1 - 0.13 12.4 41.0 0.061 13.4 19.0 3.2 1 1 1 2 2 2 0 Outer membrane protein beta-barrel domain Sugarporin_N PF11471.8 AIM22294.1 - 0.2 11.6 0.4 0.39 10.7 0.4 1.4 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension AstE_AspA PF04952.14 AIM22295.1 - 1e-62 211.9 0.0 1.3e-62 211.6 0.0 1.0 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Peptidase_M14 PF00246.24 AIM22295.1 - 0.057 13.2 0.0 0.35 10.6 0.0 2.0 2 0 0 2 2 2 0 Zinc carboxypeptidase PreAtp-grasp PF18604.1 AIM22295.1 - 0.077 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Pre ATP-grasp domain AstB PF04996.12 AIM22296.1 - 1.6e-149 498.4 0.9 1.8e-149 498.2 0.9 1.0 1 0 0 1 1 1 1 Succinylarginine dihydrolase Aldedh PF00171.22 AIM22297.1 - 2.1e-112 376.0 0.0 2.7e-112 375.6 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AstB PF04996.12 AIM22297.1 - 2.8e-57 194.3 0.2 4.2e-57 193.8 0.2 1.2 1 0 0 1 1 1 1 Succinylarginine dihydrolase AstA PF04958.12 AIM22298.1 - 2.3e-142 473.5 0.0 2.6e-142 473.3 0.0 1.0 1 0 0 1 1 1 1 Arginine N-succinyltransferase beta subunit Molydop_binding PF01568.21 AIM22298.1 - 0.032 14.2 0.0 0.071 13.1 0.0 1.5 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain Aminotran_3 PF00202.21 AIM22299.1 - 2.4e-126 421.7 0.1 3e-126 421.3 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_5 PF00266.19 AIM22299.1 - 3.9e-05 22.8 0.0 6.9e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 AIM22299.1 - 0.00047 19.4 0.0 0.00073 18.8 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Abhydrolase_3 PF07859.13 AIM22300.1 - 4.5e-68 229.2 0.3 6.8e-68 228.7 0.3 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 AIM22300.1 - 0.00047 19.1 0.0 0.00075 18.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 AIM22300.1 - 0.0013 18.2 0.2 0.0035 16.8 0.2 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 AIM22300.1 - 0.0019 16.9 0.0 0.68 8.5 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Say1_Mug180 PF10340.9 AIM22300.1 - 0.0086 15.0 0.0 0.011 14.6 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 AIM22300.1 - 0.021 13.7 0.0 1.5 7.6 0.0 2.2 2 0 0 2 2 2 0 Carboxylesterase family Chlorophyllase PF07224.11 AIM22300.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase DUF3450 PF11932.8 AIM22300.1 - 0.23 10.7 0.3 1.3 8.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) ABC_tran PF00005.27 AIM22301.1 - 3.6e-29 102.0 0.0 4.9e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 AIM22301.1 - 2.5e-09 37.5 0.0 4.3e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 AIM22301.1 - 2e-07 31.1 1.6 0.0016 18.3 0.1 2.5 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 AIM22301.1 - 0.0015 18.8 0.8 0.009 16.3 0.8 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AIM22301.1 - 0.029 14.8 1.8 0.052 13.9 0.4 2.0 1 1 1 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 AIM22301.1 - 0.043 13.5 0.1 0.072 12.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AIM22301.1 - 0.094 12.9 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AIM22301.1 - 0.1 12.4 0.2 0.2 11.4 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AIM22301.1 - 0.14 12.0 0.2 0.24 11.3 0.2 1.3 1 0 0 1 1 1 0 RsgA GTPase ABC_tran PF00005.27 AIM22302.1 - 1.8e-26 93.2 0.0 2.7e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 AIM22302.1 - 5.4e-20 71.7 0.5 1.3e-19 70.5 0.5 1.7 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region SMC_N PF02463.19 AIM22302.1 - 5.4e-05 22.7 0.1 0.0013 18.2 0.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AIM22302.1 - 0.00013 22.3 0.1 0.0014 18.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AIM22302.1 - 0.00072 20.0 0.4 0.0022 18.4 0.4 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 AIM22302.1 - 0.0022 18.4 0.1 0.035 14.5 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 AIM22302.1 - 0.0068 15.8 0.1 0.11 11.9 0.1 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_21 PF13304.6 AIM22302.1 - 0.012 15.5 0.1 0.078 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system ATP-synt_ab PF00006.25 AIM22302.1 - 0.17 11.5 0.1 0.36 10.4 0.1 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain BPD_transp_1 PF00528.22 AIM22303.1 - 3.5e-30 105.1 9.9 3.5e-30 105.1 9.9 1.7 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 AIM22303.1 - 2.3e-13 49.9 4.9 9.1e-13 48.0 0.5 3.2 3 0 0 3 3 3 1 N-terminal TM domain of oligopeptide transport permease C BPD_transp_1 PF00528.22 AIM22304.1 - 8e-41 139.8 16.2 3e-39 134.7 12.3 2.2 1 1 1 2 2 2 2 Binding-protein-dependent transport system inner membrane component SBP_bac_5 PF00496.22 AIM22305.1 - 1.2e-76 258.1 2.2 1.7e-76 257.6 2.2 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle Aminotran_1_2 PF00155.21 AIM22306.1 - 8.5e-29 100.8 0.0 5.9e-28 98.1 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class I and II GntR PF00392.21 AIM22306.1 - 5.2e-14 51.6 0.3 1.8e-13 49.9 0.1 2.1 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family Aminotran_MocR PF12897.7 AIM22306.1 - 2.4e-07 29.9 0.0 5.1e-07 28.8 0.0 1.4 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Cyt_bd_oxida_I PF01654.17 AIM22307.1 - 1.4e-165 551.0 24.9 1.6e-165 550.8 24.9 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit I DUF4235 PF14019.6 AIM22307.1 - 0.038 14.1 1.1 0.038 14.1 1.1 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF4235) Legionella_OMP PF05150.12 AIM22307.1 - 0.13 11.1 0.1 0.23 10.4 0.1 1.3 1 0 0 1 1 1 0 Legionella pneumophila major outer membrane protein precursor Cyt_bd_oxida_II PF02322.15 AIM22308.1 - 5.6e-99 331.3 37.8 6.4e-99 331.1 37.8 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit II DUF2474 PF10617.9 AIM22309.1 - 1e-21 76.5 10.7 1.2e-21 76.2 10.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2474) DndE PF08870.11 AIM22311.1 - 0.064 13.5 0.0 0.064 13.5 0.0 1.2 1 0 0 1 1 1 0 DNA sulphur modification protein DndE FA_desaturase PF00487.24 AIM22312.1 - 5.7e-33 114.8 38.1 9.6e-33 114.1 38.1 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Rab5ip PF07019.12 AIM22312.1 - 0.0036 17.9 6.1 0.16 12.5 0.9 2.8 3 0 0 3 3 3 2 Rab5-interacting protein (Rab5ip) CbtB PF09489.10 AIM22312.1 - 0.053 13.6 1.4 0.053 13.6 1.4 2.6 2 1 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) DUF2207 PF09972.9 AIM22312.1 - 0.58 8.9 0.0 0.58 8.9 0.0 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) LptF_LptG PF03739.14 AIM22312.1 - 4 6.2 7.8 0.69 8.7 0.3 2.1 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG FA_desaturase PF00487.24 AIM22313.1 - 2.1e-33 116.2 38.0 2.1e-33 116.2 38.0 1.6 1 1 1 2 2 2 2 Fatty acid desaturase Phage_holin_3_6 PF07332.11 AIM22313.1 - 5.2 7.1 12.6 2.5 8.2 3.7 2.3 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III FA_hydroxylase PF04116.13 AIM22314.1 - 6.7e-27 94.4 16.4 6.7e-27 94.4 16.4 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily PAP2_3 PF14378.6 AIM22315.1 - 1.1e-09 38.3 12.0 2.1e-09 37.4 12.0 1.4 1 1 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.21 AIM22315.1 - 2.5e-07 30.6 1.9 2.5e-07 30.6 1.9 1.8 1 1 1 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 AIM22315.1 - 0.075 13.6 0.1 0.19 12.3 0.1 1.6 1 0 0 1 1 1 0 PAP2 superfamily C-terminal CPP1-like PF11833.8 AIM22315.1 - 0.31 10.7 5.4 0.12 12.0 2.1 2.0 1 1 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Epimerase PF01370.21 AIM22317.1 - 1.7e-28 99.7 0.0 2e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 AIM22317.1 - 3.6e-18 65.5 0.0 4.3e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 AIM22317.1 - 6.4e-15 55.5 0.0 1.6e-14 54.3 0.0 1.6 1 1 1 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 AIM22317.1 - 1.6e-12 47.5 0.0 6.4e-12 45.5 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 AIM22317.1 - 8.4e-12 44.8 0.0 1.2e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 AIM22317.1 - 1.9e-09 37.1 0.0 4.7e-09 35.8 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 AIM22317.1 - 2.2e-07 30.5 0.5 9.1e-07 28.5 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.13 AIM22317.1 - 2.4e-05 24.0 0.0 3.8e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 AIM22317.1 - 8.8e-05 21.8 0.0 0.00017 20.8 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 AIM22317.1 - 0.0005 20.0 0.1 0.0009 19.2 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 AIM22317.1 - 0.013 15.0 1.3 0.014 15.0 0.2 1.7 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase ACP_syn_III_C PF08541.10 AIM22318.1 - 7e-24 83.8 0.5 1.6e-23 82.7 0.5 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 AIM22318.1 - 8.9e-21 73.5 0.3 2.8e-20 71.9 0.3 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 AIM22318.1 - 3.4e-05 23.4 0.5 6.2e-05 22.5 0.2 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain FAE1_CUT1_RppA PF08392.12 AIM22318.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 FAE1/Type III polyketide synthase-like protein Nitrate_red_gam PF02665.14 AIM22319.1 - 2.2e-81 272.6 8.8 2.5e-81 272.4 8.8 1.0 1 0 0 1 1 1 1 Nitrate reductase gamma subunit Gram_pos_anchor PF00746.21 AIM22319.1 - 0.66 10.0 2.4 1.6 8.8 1.1 2.2 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Nitrate_red_del PF02613.15 AIM22320.1 - 4e-12 46.3 1.1 4e-12 46.3 1.1 1.9 2 1 0 2 2 2 1 Nitrate reductase delta subunit 3HCDH_RFF PF18321.1 AIM22320.1 - 3.9 8.0 9.5 1.7 9.1 2.5 3.0 3 1 1 4 4 4 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain Fer4_11 PF13247.6 AIM22321.1 - 4.8e-37 126.1 5.1 1.1e-36 125.0 5.1 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Nitr_red_bet_C PF14711.6 AIM22321.1 - 6e-30 102.8 0.1 1e-29 102.0 0.1 1.4 1 0 0 1 1 1 1 Respiratory nitrate reductase beta C-terminal Fer4_10 PF13237.6 AIM22321.1 - 3.5e-08 33.4 15.2 3.2e-05 24.0 3.3 3.3 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 AIM22321.1 - 8.1e-08 32.7 17.4 0.00012 22.6 5.6 3.6 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 AIM22321.1 - 6.6e-06 26.0 18.6 0.0051 16.8 0.1 3.9 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4_9 PF13187.6 AIM22321.1 - 0.0013 18.9 18.4 0.011 15.9 4.0 3.3 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AIM22321.1 - 0.0067 16.5 22.3 0.014 15.5 1.9 4.0 4 0 0 4 4 3 3 4Fe-4S binding domain Fer4 PF00037.27 AIM22321.1 - 0.016 15.0 2.0 0.016 15.0 2.0 4.8 5 0 0 5 5 4 0 4Fe-4S binding domain Fer4_13 PF13370.6 AIM22321.1 - 0.048 14.2 0.1 0.048 14.2 0.1 3.4 2 1 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_21 PF14697.6 AIM22321.1 - 0.05 13.7 20.5 0.076 13.2 0.9 3.1 3 1 0 3 3 3 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 AIM22321.1 - 0.079 13.5 12.7 1.2 9.8 0.1 3.9 3 1 0 3 3 3 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 AIM22321.1 - 0.19 12.5 10.6 1.7 9.5 0.1 3.4 3 0 0 3 3 3 0 4Fe-4S single cluster domain Fer4_8 PF13183.6 AIM22321.1 - 0.2 12.1 0.1 0.2 12.1 0.1 3.7 3 1 1 4 4 3 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 AIM22321.1 - 6 7.6 24.0 2.6 8.8 1.5 3.9 4 0 0 4 4 3 0 4Fe-4S binding domain Molybdopterin PF00384.22 AIM22322.1 - 3.4e-172 573.3 0.0 4.2e-172 573.0 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 AIM22322.1 - 2.6e-20 72.5 0.0 9.9e-20 70.6 0.0 2.0 2 0 0 2 2 2 1 Molydopterin dinucleotide binding domain Nitr_red_alph_N PF14710.6 AIM22322.1 - 1.5e-14 54.1 2.1 5.3e-14 52.4 2.1 2.1 1 0 0 1 1 1 1 Respiratory nitrate reductase alpha N-terminal Molybdop_Fe4S4 PF04879.16 AIM22322.1 - 0.0031 17.5 0.1 0.0077 16.2 0.1 1.7 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain Glycos_transf_2 PF00535.26 AIM22323.1 - 2.5e-29 102.3 0.0 3.5e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AIM22323.1 - 1.2e-15 58.1 0.0 2.2e-15 57.2 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 AIM22323.1 - 1e-07 31.7 0.0 1.5e-07 31.2 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 AIM22324.1 - 2.5e-27 95.8 0.0 3.7e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AIM22324.1 - 2.8e-14 53.6 0.0 3.6e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 AIM22324.1 - 1.9e-08 34.1 0.0 3e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AIM22324.1 - 0.0068 16.9 0.0 0.02 15.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 PikAIV_N PF18605.1 AIM22324.1 - 0.0095 15.5 8.7 1 9.0 5.7 2.4 2 0 0 2 2 2 2 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain HALZ PF02183.18 AIM22324.1 - 0.14 12.4 0.1 3.7 7.9 0.0 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper Osmo_MPGsynth PF09488.10 AIM22324.1 - 0.31 9.7 0.1 1.2 7.7 0.0 1.7 1 1 1 2 2 2 0 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) CBM_4_9 PF02018.17 AIM22325.1 - 4e-05 23.9 0.0 9e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate binding domain DUF4469 PF14734.6 AIM22325.1 - 0.012 15.8 0.0 0.41 10.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4469) with IG-like fold MG2 PF01835.19 AIM22325.1 - 0.024 15.1 0.1 2.8 8.4 0.1 2.7 2 0 0 2 2 2 0 MG2 domain DUF4038 PF13204.6 AIM22325.1 - 0.03 14.0 0.1 0.058 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4038) DUF4434 PF14488.6 AIM22325.1 - 0.04 13.9 0.1 0.073 13.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) Glyco_hydro_42 PF02449.15 AIM22325.1 - 0.092 12.1 0.1 9.5 5.4 0.0 2.2 1 1 1 2 2 2 0 Beta-galactosidase Glycos_transf_2 PF00535.26 AIM22326.1 - 1.3e-35 122.7 0.4 1.8e-35 122.3 0.4 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AIM22326.1 - 5.5e-16 59.2 0.3 9.2e-16 58.4 0.1 1.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 AIM22326.1 - 2.4e-14 53.5 0.9 5.7e-14 52.2 0.1 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AIM22326.1 - 2e-06 28.2 0.8 4.2e-06 27.2 0.2 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 AIM22326.1 - 0.0022 17.5 0.0 0.0033 16.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 AIM22326.1 - 0.17 11.8 1.4 3 7.7 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family group 2 Glycos_transf_1 PF00534.20 AIM22327.1 - 4.1e-39 133.8 0.0 5.9e-39 133.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AIM22327.1 - 6.3e-32 110.8 0.0 9.4e-32 110.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AIM22327.1 - 3.3e-10 40.2 0.9 1.4e-09 38.2 0.1 2.2 2 1 1 3 3 3 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 AIM22327.1 - 8.8e-07 29.2 0.0 1.9e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_2 PF00535.26 AIM22328.1 - 1.4e-12 47.7 0.1 2e-12 47.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AIM22328.1 - 4.5e-05 23.4 0.0 5.5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 AIM22328.1 - 0.00012 21.7 0.1 0.00017 21.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 ATPgrasp_TupA PF14305.6 AIM22329.1 - 7e-48 163.5 0.2 7.9e-48 163.3 0.2 1.0 1 0 0 1 1 1 1 TupA-like ATPgrasp Polysacc_synt PF01943.17 AIM22330.1 - 2e-23 83.1 20.9 2e-23 83.1 20.9 2.1 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein Polysacc_synt_3 PF13440.6 AIM22330.1 - 1.7e-15 57.1 16.4 1.7e-15 57.1 16.4 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Polysacc_synt_C PF14667.6 AIM22330.1 - 1.2e-09 38.4 8.7 1.2e-09 38.4 8.7 4.3 2 1 3 5 5 5 1 Polysaccharide biosynthesis C-terminal domain GNVR PF13807.6 AIM22331.1 - 2.4e-31 107.5 2.9 2.4e-31 107.5 2.9 2.1 2 0 0 2 2 1 1 G-rich domain on putative tyrosine kinase Wzz PF02706.15 AIM22331.1 - 7.6e-14 51.8 0.0 7.6e-14 51.8 0.0 2.9 3 0 0 3 3 3 1 Chain length determinant protein AAA_31 PF13614.6 AIM22331.1 - 7e-12 45.6 0.1 9.7e-11 41.9 0.0 2.7 2 1 2 4 4 4 1 AAA domain CbiA PF01656.23 AIM22331.1 - 1.7e-07 31.3 0.1 6.3e-07 29.5 0.0 1.9 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.6 AIM22331.1 - 9.4e-06 25.6 0.5 0.0062 16.4 0.0 2.9 3 0 0 3 3 3 2 AAA domain MipZ PF09140.11 AIM22331.1 - 8.6e-05 21.9 0.0 0.00026 20.4 0.0 1.7 1 1 0 1 1 1 1 ATPase MipZ ParA PF10609.9 AIM22331.1 - 0.00011 21.7 0.3 0.0007 19.1 0.3 2.1 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase AAA_25 PF13481.6 AIM22331.1 - 0.0035 16.9 0.4 0.0086 15.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain Fer4_NifH PF00142.18 AIM22331.1 - 0.026 14.0 0.0 0.092 12.2 0.0 1.9 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Peptidase_S46 PF10459.9 AIM22331.1 - 0.36 9.4 7.9 0.51 8.9 7.9 1.1 1 0 0 1 1 1 0 Peptidase S46 ArsA_ATPase PF02374.15 AIM22331.1 - 1.1 8.3 7.3 20 4.2 0.0 4.0 3 2 1 4 4 4 0 Anion-transporting ATPase V_ATPase_I PF01496.19 AIM22331.1 - 3.8 5.3 8.7 5.3 4.8 8.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Occludin_ELL PF07303.13 AIM22331.1 - 4 8.2 6.7 2.4 8.9 0.5 2.6 1 1 1 3 3 3 0 Occludin homology domain BST2 PF16716.5 AIM22331.1 - 6.6 7.4 16.9 6.6 7.4 8.9 2.6 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 Poly_export PF02563.16 AIM22332.1 - 9.3e-29 99.5 0.4 7.3e-27 93.4 0.1 3.1 3 1 0 3 3 3 1 Polysaccharide biosynthesis/export protein Wza_C PF18412.1 AIM22332.1 - 3.6e-17 61.8 0.5 9.3e-17 60.5 0.5 1.8 1 0 0 1 1 1 1 Outer-membrane lipoprotein Wza C-terminal domain SLBB PF10531.9 AIM22332.1 - 1.8e-12 46.9 0.7 9.7e-08 31.8 0.0 2.7 2 0 0 2 2 2 2 SLBB domain Cupin_4 PF08007.12 AIM22332.1 - 0.044 13.2 0.0 0.094 12.2 0.0 1.4 1 0 0 1 1 1 0 Cupin superfamily protein Glycos_transf_4 PF00953.21 AIM22333.1 - 1.2e-28 100.1 17.2 1.2e-28 100.1 17.2 2.6 3 0 0 3 3 3 2 Glycosyl transferase family 4 Phage_C PF12025.8 AIM22333.1 - 0.06 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Phage protein C Epimerase PF01370.21 AIM22334.1 - 4.7e-13 49.2 0.2 6.1e-13 48.8 0.2 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 AIM22334.1 - 4.3e-09 35.8 0.2 6.1e-09 35.3 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 AIM22334.1 - 1.6e-06 27.7 0.1 2.1e-06 27.4 0.1 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 AIM22334.1 - 1.3e-05 24.5 0.0 1.4e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 AIM22334.1 - 3.1e-05 23.3 0.0 4.6e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 AIM22334.1 - 0.072 12.2 0.0 0.087 11.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Plus-3 PF03126.18 AIM22334.1 - 0.12 12.9 0.3 11 6.6 0.1 2.3 2 0 0 2 2 2 0 Plus-3 domain MFS_1 PF07690.16 AIM22337.1 - 2.3e-14 53.1 99.1 6.5e-13 48.3 64.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Bac_export_2 PF01312.19 AIM22337.1 - 0.45 9.7 12.2 4.7 6.3 0.0 3.3 2 1 0 3 3 3 0 FlhB HrpN YscU SpaS Family Sprouty PF05210.13 AIM22337.1 - 0.86 10.0 2.6 0.89 10.0 0.2 2.0 2 0 0 2 2 2 0 Sprouty protein (Spry) HisKA_3 PF07730.13 AIM22338.1 - 1.2e-17 64.2 3.5 7.8e-17 61.6 3.5 2.5 1 0 0 1 1 1 1 Histidine kinase HAMP PF00672.25 AIM22338.1 - 2.2e-11 43.9 0.3 7.3e-11 42.3 0.3 2.0 1 0 0 1 1 1 1 HAMP domain PilJ PF13675.6 AIM22338.1 - 4.1e-10 39.7 3.5 4.1e-10 39.7 3.5 3.9 3 1 0 4 4 4 1 Type IV pili methyl-accepting chemotaxis transducer N-term HATPase_c PF02518.26 AIM22338.1 - 8.5e-08 32.7 0.0 5.9e-07 30.0 0.0 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AIM22338.1 - 0.0016 18.4 0.0 0.0035 17.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain FNIP_M PF14637.6 AIM22338.1 - 0.012 15.6 1.5 0.14 12.1 0.3 2.8 2 1 1 3 3 3 0 Folliculin-interacting protein middle domain DUF4515 PF14988.6 AIM22338.1 - 0.31 10.9 8.5 0.12 12.2 5.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4515) SKA2 PF16740.5 AIM22338.1 - 0.62 9.9 10.8 0.47 10.3 6.4 2.7 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Spectrin PF00435.21 AIM22338.1 - 0.66 10.5 6.7 10 6.7 4.6 3.1 2 1 0 2 2 2 0 Spectrin repeat Baculo_PEP_C PF04513.12 AIM22338.1 - 1.1 9.3 9.4 22 5.1 0.2 3.2 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Oleosin PF01277.17 AIM22338.1 - 8.8 6.1 6.6 0.75 9.6 0.2 2.4 2 0 0 2 2 2 0 Oleosin Response_reg PF00072.24 AIM22339.1 - 1.3e-31 109.0 0.2 2.1e-31 108.4 0.2 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AIM22339.1 - 8.6e-22 76.5 0.4 1.6e-21 75.6 0.4 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AIM22339.1 - 4.4e-09 35.9 0.2 8.2e-09 35.0 0.2 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AIM22339.1 - 6.5e-06 25.6 0.6 1.6e-05 24.3 0.6 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 AIM22339.1 - 4.6e-05 23.1 0.1 0.00017 21.3 0.1 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_24 PF13412.6 AIM22339.1 - 0.00018 21.0 0.3 0.00039 19.9 0.3 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 AIM22339.1 - 0.04 14.1 0.1 0.44 10.7 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_20 PF12840.7 AIM22339.1 - 0.044 13.9 0.1 0.11 12.6 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 AIM22339.1 - 0.053 13.3 0.2 0.17 11.7 0.1 2.0 2 0 0 2 2 2 0 Homeodomain-like domain HTH_11 PF08279.12 AIM22339.1 - 0.15 12.1 0.8 0.45 10.5 0.8 1.9 1 0 0 1 1 1 0 HTH domain Trans_reg_C PF00486.28 AIM22339.1 - 0.15 12.1 0.5 5.1 7.2 0.5 2.5 1 1 0 1 1 1 0 Transcriptional regulatory protein, C terminal IAT_beta PF11924.8 AIM22340.1 - 4.7e-87 291.9 0.8 6.4e-87 291.5 0.8 1.1 1 0 0 1 1 1 1 Inverse autotransporter, beta-domain Peptidase_A24 PF01478.18 AIM22341.1 - 4e-25 88.3 6.2 4e-25 88.3 6.2 2.1 2 0 0 2 2 2 1 Type IV leader peptidase family TctB PF07331.11 AIM22341.1 - 1.5 9.1 19.2 0.44 10.8 6.2 2.3 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family EpsG PF14897.6 AIM22342.1 - 1.2e-23 84.0 29.7 1.3e-23 83.8 29.0 1.4 1 1 0 1 1 1 1 EpsG family SBP_bac_5 PF00496.22 AIM22343.1 - 9.2e-58 196.0 0.6 1.1e-57 195.7 0.6 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle ABC_tran PF00005.27 AIM22344.1 - 3.8e-30 105.2 0.0 4.9e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIM22344.1 - 1.3e-13 51.5 6.3 3.7e-09 36.8 0.3 3.0 1 1 2 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIM22344.1 - 6.4e-06 25.8 0.0 0.0061 16.0 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AIM22344.1 - 7.8e-06 26.4 0.2 1.1e-05 25.9 0.2 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 AIM22344.1 - 0.0011 19.3 0.0 0.76 10.2 0.0 2.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 AIM22344.1 - 0.014 15.3 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase TniB PF05621.11 AIM22344.1 - 0.016 14.6 0.3 0.64 9.4 0.1 2.6 2 1 1 3 3 3 0 Bacterial TniB protein AAA_29 PF13555.6 AIM22344.1 - 0.033 13.9 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 AIM22344.1 - 0.039 14.2 1.5 0.42 10.9 1.5 2.2 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 AIM22344.1 - 0.044 13.8 0.4 1.6 8.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 AIM22344.1 - 0.046 14.0 0.1 0.68 10.2 0.1 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 AIM22344.1 - 0.092 12.3 0.0 1.8 8.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 AIM22344.1 - 0.094 12.4 0.1 0.71 9.6 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein Rad17 PF03215.15 AIM22344.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain ABC_tran PF00005.27 AIM22345.1 - 3.1e-23 82.8 0.0 4.5e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AIM22345.1 - 2.1e-06 27.3 0.0 5.1e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AIM22345.1 - 4.8e-05 23.7 0.7 0.0012 19.1 0.7 2.3 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 AIM22345.1 - 0.00014 21.4 0.1 0.00094 18.6 0.1 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_21 PF13304.6 AIM22345.1 - 0.00017 21.5 0.0 0.011 15.5 0.1 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AIM22345.1 - 0.0014 19.0 0.8 0.0051 17.2 0.8 1.8 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 AIM22345.1 - 0.0047 16.7 0.1 1.1 8.9 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein NACHT PF05729.12 AIM22345.1 - 0.014 15.4 0.4 2.9 7.8 0.0 2.5 3 0 0 3 3 3 0 NACHT domain AAA_29 PF13555.6 AIM22345.1 - 0.037 13.8 0.0 0.071 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pox_A32 PF04665.12 AIM22345.1 - 0.12 11.9 1.9 3.7 6.9 0.1 2.1 2 0 0 2 2 2 0 Poxvirus A32 protein DUF87 PF01935.17 AIM22345.1 - 0.15 12.2 0.1 0.27 11.3 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain BPD_transp_1 PF00528.22 AIM22346.1 - 6.1e-26 91.3 8.8 6.1e-26 91.3 8.8 2.2 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 AIM22346.1 - 0.00021 21.2 1.9 0.00021 21.2 1.9 3.3 4 0 0 4 4 4 1 N-terminal TM domain of oligopeptide transport permease C DUF4658 PF15555.6 AIM22346.1 - 0.088 12.9 0.3 0.19 11.8 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4658) BPD_transp_1 PF00528.22 AIM22347.1 - 1.8e-42 145.2 11.4 1.8e-42 145.2 11.4 1.7 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component SBP_bac_5 PF00496.22 AIM22348.1 - 5.2e-65 219.9 1.8 8.1e-65 219.2 1.8 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle LysR_substrate PF03466.20 AIM22349.1 - 9.4e-43 146.0 0.1 1.4e-42 145.5 0.1 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM22349.1 - 9.3e-13 47.9 0.0 1.7e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_24 PF13412.6 AIM22349.1 - 0.0039 16.7 0.1 0.01 15.4 0.1 1.8 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_30 PF13556.6 AIM22349.1 - 0.021 14.6 0.1 0.045 13.6 0.1 1.6 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_20 PF12840.7 AIM22349.1 - 0.031 14.3 0.0 0.077 13.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain PBP_like_2 PF12849.7 AIM22349.1 - 0.17 11.5 0.0 1 8.9 0.0 1.8 1 1 0 2 2 2 0 PBP superfamily domain ChaC PF04752.12 AIM22350.1 - 7.9e-50 169.4 0.0 9.4e-50 169.1 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein GGACT PF06094.12 AIM22350.1 - 4e-05 24.2 0.0 6.3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like DUF2780 PF11075.8 AIM22350.1 - 0.13 12.4 0.0 0.19 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function VcgC/VcgE (DUF2780) ChaB PF06150.12 AIM22351.1 - 9.1e-27 93.4 4.7 1e-26 93.2 4.7 1.1 1 0 0 1 1 1 1 ChaB FAD_binding_9 PF08021.11 AIM22352.1 - 1.8e-36 125.0 0.1 2.7e-36 124.4 0.1 1.3 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain SIP PF04954.13 AIM22352.1 - 7.8e-34 116.7 0.0 1.2e-33 116.1 0.0 1.3 1 0 0 1 1 1 1 Siderophore-interacting protein Na_Ca_ex PF01699.24 AIM22353.1 - 5.7e-23 81.6 37.1 1e-13 51.5 16.2 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Asp_Arg_Hydrox PF05118.15 AIM22354.1 - 4.5e-48 163.0 0.0 6.6e-48 162.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Cupin_2 PF07883.11 AIM22354.1 - 0.055 13.2 0.0 0.25 11.1 0.0 1.9 2 0 0 2 2 2 0 Cupin domain PhoH PF02562.16 AIM22355.1 - 6.2e-78 261.0 0.0 7.7e-78 260.6 0.0 1.1 1 0 0 1 1 1 1 PhoH-like protein AAA_30 PF13604.6 AIM22355.1 - 1.5e-08 34.6 0.0 3e-08 33.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 AIM22355.1 - 2.3e-05 24.8 0.0 0.028 14.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 AIM22355.1 - 5.3e-05 23.5 0.1 0.00041 20.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 AIM22355.1 - 0.021 14.4 0.4 2.2 7.7 0.1 2.1 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain DEAD PF00270.29 AIM22355.1 - 0.027 14.2 0.1 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase Viral_helicase1 PF01443.18 AIM22355.1 - 0.028 14.2 0.0 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 AIM22355.1 - 0.063 13.0 0.0 0.14 11.9 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF2075 PF09848.9 AIM22355.1 - 0.066 12.4 0.3 0.49 9.6 0.3 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 AIM22355.1 - 0.11 12.9 0.0 1.5 9.2 0.0 2.4 1 1 0 1 1 1 0 AAA ATPase domain DEAD_2 PF06733.15 AIM22355.1 - 0.11 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 DEAD_2 ResIII PF04851.15 AIM22355.1 - 0.13 12.3 0.0 0.45 10.5 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_14 PF13173.6 AIM22355.1 - 0.17 11.9 0.0 7.3 6.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain Dyp_perox PF04261.12 AIM22356.1 - 1e-115 386.2 0.0 1.2e-115 386.0 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family Peptidase_M75 PF09375.10 AIM22357.1 - 1.2e-41 143.0 0.2 1.6e-41 142.7 0.2 1.1 1 0 0 1 1 1 1 Imelysin Cupredoxin_1 PF13473.6 AIM22357.1 - 1.6e-24 86.0 0.1 2.7e-24 85.3 0.1 1.3 1 0 0 1 1 1 1 Cupredoxin-like domain DUF4363 PF14276.6 AIM22357.1 - 0.14 12.2 0.0 0.99 9.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) FTR1 PF03239.14 AIM22358.1 - 2.5e-70 237.1 20.7 3.1e-70 236.8 20.7 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family MFS_1 PF07690.16 AIM22358.1 - 0.00012 21.1 21.7 0.00012 21.1 21.7 1.8 1 1 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 AIM22358.1 - 0.03 12.6 1.2 0.042 12.1 0.1 1.8 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family CoxIIa PF08113.11 AIM22358.1 - 0.064 13.1 1.3 0.064 13.1 1.3 3.9 4 0 0 4 4 4 0 Cytochrome c oxidase subunit IIa family Abhydrolase_9_N PF15420.6 AIM22358.1 - 0.33 10.9 14.5 0.56 10.2 13.9 1.7 1 1 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus Popeye PF04831.13 AIM22358.1 - 1.1 9.4 7.1 3.5 7.8 1.9 2.5 2 0 0 2 2 2 0 Popeye protein conserved region DUF1385 PF07136.11 AIM22358.1 - 2.3 7.5 6.8 0.079 12.2 0.4 1.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1385) Glycos_transf_2 PF00535.26 AIM22359.1 - 2.1e-33 115.5 0.1 3.6e-33 114.8 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AIM22359.1 - 1e-16 61.5 0.0 2.1e-16 60.5 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 AIM22359.1 - 4.7e-11 42.7 0.2 7e-11 42.1 0.2 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AIM22359.1 - 3.9e-07 30.5 0.0 9.9e-07 29.2 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 AIM22359.1 - 0.064 12.7 0.1 0.12 11.8 0.1 1.6 1 1 0 1 1 1 0 Glycosyl transferase family 21 NUC130_3NT PF08158.12 AIM22359.1 - 0.13 12.6 0.0 0.47 10.8 0.0 2.0 2 0 0 2 2 2 0 NUC130/3NT domain SSF PF00474.17 AIM22360.1 - 1.2e-141 472.3 31.5 1.8e-141 471.7 31.5 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family 4HB_MCP_1 PF12729.7 AIM22360.1 - 0.0089 15.6 0.2 0.54 9.8 0.2 2.7 2 0 0 2 2 2 2 Four helix bundle sensory module for signal transduction Aldedh PF00171.22 AIM22361.1 - 4.3e-116 388.2 0.2 7e-116 387.5 0.2 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pro_dh PF01619.18 AIM22361.1 - 2.6e-100 335.8 0.0 5.6e-100 334.7 0.0 1.6 1 0 0 1 1 1 1 Proline dehydrogenase Pro_dh-DNA_bdg PF14850.6 AIM22361.1 - 9e-46 155.0 0.0 2.4e-45 153.7 0.0 1.8 1 0 0 1 1 1 1 DNA-binding domain of Proline dehydrogenase PRODH PF18327.1 AIM22361.1 - 2.9e-18 65.8 4.2 2.9e-18 65.8 4.2 4.2 4 0 0 4 4 4 1 Proline utilization A proline dehydrogenase N-terminal domain RHH_1 PF01402.21 AIM22361.1 - 0.081 12.9 0.1 0.77 9.8 0.0 2.9 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family ABC_tran PF00005.27 AIM22362.1 - 2.2e-35 122.2 0.0 3.3e-35 121.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIM22362.1 - 3.7e-14 53.2 0.1 7.6e-06 25.9 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIM22362.1 - 2.3e-09 37.0 0.0 3.8e-09 36.3 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AIM22362.1 - 1.1e-06 29.0 0.1 1.2e-05 25.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AIM22362.1 - 1.8e-05 25.2 0.5 5e-05 23.8 0.5 1.8 1 1 0 1 1 1 1 AAA ATPase domain ABC_ATPase PF09818.9 AIM22362.1 - 4.6e-05 22.4 0.6 0.2 10.4 0.0 2.9 2 1 0 2 2 2 2 Predicted ATPase of the ABC class AAA_13 PF13166.6 AIM22362.1 - 4.8e-05 22.2 0.0 0.015 14.0 0.0 2.1 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 AIM22362.1 - 5.3e-05 23.8 0.1 0.00011 22.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AIM22362.1 - 0.0003 20.5 0.0 0.00055 19.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATPase_2 PF01637.18 AIM22362.1 - 0.00035 20.6 0.0 0.018 15.0 0.0 2.0 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_15 PF13175.6 AIM22362.1 - 0.00035 20.4 0.0 0.085 12.5 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 AIM22362.1 - 0.00049 19.9 0.0 0.00091 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 AIM22362.1 - 0.0015 18.1 0.3 0.088 12.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 AIM22362.1 - 0.0069 16.6 0.1 0.014 15.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 AIM22362.1 - 0.0075 16.7 0.3 0.2 12.1 0.3 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 AIM22362.1 - 0.0089 15.9 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase NACHT PF05729.12 AIM22362.1 - 0.011 15.7 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 AIM22362.1 - 0.011 15.4 0.0 0.023 14.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 AIM22362.1 - 0.015 14.7 0.1 1.7 8.0 0.0 2.5 2 0 0 2 2 2 0 Bacterial TniB protein T2SSE PF00437.20 AIM22362.1 - 0.03 13.4 0.1 0.061 12.4 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein cobW PF02492.19 AIM22362.1 - 0.03 13.9 0.0 0.06 12.9 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 AIM22362.1 - 0.038 14.2 0.3 0.15 12.3 0.1 2.0 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 AIM22362.1 - 0.041 14.4 0.0 0.077 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 AIM22362.1 - 0.048 13.6 0.0 0.091 12.7 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.22 AIM22362.1 - 0.059 12.5 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.6 AIM22362.1 - 0.06 13.7 0.0 0.18 12.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain PCP_red PF08369.10 AIM22362.1 - 0.074 13.3 0.1 0.15 12.3 0.1 1.5 1 0 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit Mg_chelatase PF01078.21 AIM22362.1 - 0.079 12.3 0.1 0.27 10.6 0.0 1.9 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI SbcCD_C PF13558.6 AIM22362.1 - 0.08 13.2 0.1 0.86 9.9 0.1 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Pox_A32 PF04665.12 AIM22362.1 - 0.14 11.6 0.0 1.2 8.5 0.0 2.0 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_5 PF07728.14 AIM22362.1 - 0.14 12.1 0.1 3.2 7.8 0.1 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 AIM22362.1 - 0.14 12.2 0.0 0.86 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 AIM22362.1 - 0.19 11.7 0.1 0.33 10.9 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE BPD_transp_1 PF00528.22 AIM22363.1 - 5.7e-27 94.6 9.2 8.6e-27 94.1 9.2 1.2 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component SBP_bac_3 PF00497.20 AIM22364.1 - 2.6e-73 246.2 0.3 3.6e-73 245.7 0.3 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 AIM22364.1 - 7.3e-12 45.5 0.0 3.8e-11 43.2 0.0 2.0 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site NMT1 PF09084.11 AIM22364.1 - 0.012 15.6 0.2 0.058 13.3 0.1 2.0 1 1 1 2 2 2 0 NMT1/THI5 like PALP PF00291.25 AIM22365.1 - 1.2e-53 182.4 0.7 1.4e-53 182.2 0.7 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme FIST PF08495.10 AIM22365.1 - 0.12 12.4 0.4 0.57 10.2 0.0 2.0 1 1 1 2 2 2 0 FIST N domain Phage_int_SAM_1 PF02899.17 AIM22366.1 - 1.6e-07 31.5 1.3 1e-06 29.0 1.3 2.2 1 1 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain RecR PF02132.15 AIM22366.1 - 0.016 14.8 0.4 0.17 11.5 0.0 2.3 2 0 0 2 2 2 0 RecR protein Phage_int_SAM_5 PF13102.6 AIM22366.1 - 0.02 15.2 0.8 0.067 13.5 0.1 2.3 3 1 0 3 3 3 0 Phage integrase SAM-like domain DUF2703 PF10865.8 AIM22366.1 - 0.024 14.8 0.3 8.3 6.6 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF2703) HBD PF18534.1 AIM22366.1 - 0.064 13.4 0.1 0.16 12.1 0.1 1.6 1 0 0 1 1 1 0 Helical bundle domain Sigma70_r4 PF04545.16 AIM22367.1 - 1.3e-20 72.7 3.7 4.3e-17 61.4 0.7 2.5 2 0 0 2 2 2 2 Sigma-70, region 4 Sigma70_r2 PF04542.14 AIM22367.1 - 7.8e-17 60.8 2.9 6.6e-16 57.9 0.3 2.5 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r3 PF04539.16 AIM22367.1 - 1.4e-16 60.3 0.6 2.9e-16 59.3 0.3 1.7 2 0 0 2 2 2 1 Sigma-70 region 3 Sigma70_r4_2 PF08281.12 AIM22367.1 - 5e-10 38.9 1.7 1.6e-09 37.3 0.6 2.3 2 0 0 2 2 2 1 Sigma-70, region 4 UPF0147 PF03685.13 AIM22367.1 - 0.018 15.1 0.1 0.045 13.8 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) UPF0122 PF04297.14 AIM22367.1 - 0.036 14.3 0.2 0.13 12.5 0.0 1.9 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like TFIIE_alpha PF02002.17 AIM22367.1 - 0.039 13.8 0.2 0.11 12.4 0.0 1.9 2 1 0 2 2 2 0 TFIIE alpha subunit GerE PF00196.19 AIM22367.1 - 0.11 12.1 0.1 0.7 9.5 0.1 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family Flagellin_N PF00669.20 AIM22368.1 - 3.1e-46 157.0 20.7 3.1e-46 157.0 20.7 2.9 2 1 1 3 3 3 1 Bacterial flagellin N-terminal helical region Flagellin_C PF00700.21 AIM22368.1 - 4.2e-27 94.3 9.4 4.2e-27 94.3 9.4 3.9 2 1 1 3 3 3 2 Bacterial flagellin C-terminal helical region DUF948 PF06103.11 AIM22368.1 - 0.085 13.1 8.3 3.4 8.0 2.0 3.5 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF2031 PF09592.10 AIM22368.1 - 0.34 10.4 5.0 0.18 11.3 2.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2031) Sec34 PF04136.15 AIM22368.1 - 0.45 10.4 6.8 6.1 6.7 0.1 2.6 3 0 0 3 3 3 0 Sec34-like family DUF2408 PF10303.9 AIM22368.1 - 0.57 10.7 3.7 2.4 8.7 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2408) DUF3829 PF12889.7 AIM22368.1 - 0.78 9.2 9.1 0.18 11.3 1.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3829) HAUS-augmin3 PF14932.6 AIM22368.1 - 6.9 6.2 8.1 4.3 6.9 0.8 2.5 3 0 0 3 3 3 0 HAUS augmin-like complex subunit 3 NPV_P10 PF05531.12 AIM22368.1 - 8.6 6.9 12.0 2.5 8.6 0.7 3.1 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein FliD_C PF07195.12 AIM22369.1 - 1.5e-61 207.8 12.2 1.5e-61 207.8 12.2 2.2 3 0 0 3 3 3 1 Flagellar hook-associated protein 2 C-terminus FliD_N PF02465.18 AIM22369.1 - 9.2e-21 74.4 1.3 9.2e-21 74.4 1.3 4.2 3 1 1 4 4 4 1 Flagellar hook-associated protein 2 N-terminus RuvC PF02075.17 AIM22369.1 - 0.0045 16.9 0.6 0.017 15.0 0.3 2.1 2 0 0 2 2 2 1 Crossover junction endodeoxyribonuclease RuvC TolA_bind_tri PF16331.5 AIM22369.1 - 0.006 16.6 0.0 0.019 15.1 0.0 1.8 1 0 0 1 1 1 1 TolA binding protein trimerisation Pr_beta_C PF12465.8 AIM22369.1 - 0.036 13.5 0.1 0.12 11.8 0.0 1.9 2 0 0 2 2 2 0 Proteasome beta subunits C terminal DUF948 PF06103.11 AIM22369.1 - 0.1 12.9 3.5 0.71 10.2 0.5 2.9 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Sec34 PF04136.15 AIM22369.1 - 1.1 9.1 5.9 0.27 11.1 0.8 2.5 3 0 0 3 3 3 0 Sec34-like family DUF4854 PF16146.5 AIM22369.1 - 1.6 9.1 6.1 9.7 6.6 0.2 3.7 2 2 1 3 3 3 0 Domain of unknown function (DUF4854) FliS PF02561.14 AIM22370.1 - 2.3e-40 137.5 0.4 2.5e-40 137.3 0.4 1.0 1 0 0 1 1 1 1 Flagellar protein FliS DUF4924 PF16271.5 AIM22370.1 - 0.11 12.5 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4924) FliT PF05400.13 AIM22371.1 - 1.8e-20 73.5 2.6 1.8e-20 73.5 2.6 1.6 2 0 0 2 2 2 1 Flagellar protein FliT Siah-Interact_N PF09032.11 AIM22371.1 - 0.021 15.1 1.4 0.1 12.9 0.3 2.3 1 1 1 2 2 2 0 Siah interacting protein, N terminal HTH_18 PF12833.7 AIM22372.1 - 6.6e-13 48.7 0.4 1.3e-12 47.8 0.4 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AIM22372.1 - 4.2e-09 36.3 0.1 1.5e-08 34.5 0.0 1.9 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix proteins, AraC family DUF962 PF06127.11 AIM22373.1 - 0.017 15.2 3.5 0.21 11.7 1.3 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF962) LysR_substrate PF03466.20 AIM22374.1 - 3.9e-36 124.4 1.5 5.2e-36 124.0 1.5 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM22374.1 - 8.3e-20 70.5 1.5 1.8e-19 69.5 1.5 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 AIM22374.1 - 0.00043 20.1 0.1 0.0018 18.1 0.1 2.0 1 0 0 1 1 1 1 MarR family HTH_28 PF13518.6 AIM22374.1 - 0.00082 19.4 0.0 0.0019 18.3 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AIM22374.1 - 0.0068 16.2 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_24 PF13412.6 AIM22374.1 - 0.061 12.9 0.1 0.13 11.8 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_30 PF13556.6 AIM22374.1 - 0.066 13.0 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain MarR PF01047.22 AIM22374.1 - 0.16 11.9 0.1 0.36 10.8 0.1 1.5 1 0 0 1 1 1 0 MarR family Flavodoxin_2 PF02525.17 AIM22375.1 - 1.8e-38 132.3 0.0 2e-38 132.1 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 AIM22375.1 - 5.5e-09 36.0 0.0 6.6e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase LPAM_1 PF08139.12 AIM22376.1 - 2.1 9.0 8.5 3.1 8.5 8.5 1.3 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Head_binding PF09008.10 AIM22377.1 - 6.5e-57 190.7 0.5 1.9e-56 189.2 0.5 1.9 1 0 0 1 1 1 1 Head binding Arc PF03869.14 AIM22378.1 - 1.2e-13 50.6 0.0 2.4e-13 49.7 0.0 1.5 2 0 0 2 2 2 1 Arc-like DNA binding domain Repressor_Mnt PF11423.8 AIM22378.1 - 5.5e-09 35.6 0.4 7.8e-09 35.1 0.4 1.2 1 0 0 1 1 1 1 Regulatory protein Mnt HicB PF05534.12 AIM22378.1 - 0.0017 18.2 0.0 0.0028 17.5 0.0 1.4 1 0 0 1 1 1 1 HicB family TraY PF05509.11 AIM22378.1 - 0.0026 17.7 0.0 0.0041 17.1 0.0 1.2 1 0 0 1 1 1 1 TraY domain SLT PF01464.20 AIM22379.1 - 4.4e-23 81.2 0.1 1.2e-22 79.8 0.1 1.7 1 0 0 1 1 1 1 Transglycosylase SLT domain SLT_2 PF13406.6 AIM22379.1 - 0.0045 16.3 0.2 0.57 9.4 0.2 2.8 1 1 1 2 2 2 2 Transglycosylase SLT domain Carbpep_Y_N PF05388.11 AIM22379.1 - 0.12 12.9 0.2 0.27 11.8 0.2 1.5 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide DUF456 PF04306.13 AIM22379.1 - 1.8 8.9 7.4 0.47 10.7 2.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF456) Inj_translocase PF16928.5 AIM22380.1 - 5.2e-69 232.0 22.0 5.2e-69 232.0 22.0 2.5 1 1 2 3 3 3 1 DNA/protein translocase of phage P22 injectosome FlaC_arch PF05377.11 AIM22380.1 - 0.14 12.5 0.1 0.36 11.2 0.1 1.7 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF4298 PF14131.6 AIM22381.1 - 0.054 13.5 0.1 0.086 12.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) DUF4807 PF16065.5 AIM22381.1 - 0.14 11.9 2.5 0.58 9.8 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4807) DUF2824 PF11039.8 AIM22382.1 - 2.4e-50 170.4 0.1 2.7e-50 170.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2824) Tropomyosin PF00261.20 AIM22383.1 - 1.5e-05 24.5 8.0 7.6e-05 22.2 6.8 2.5 2 1 0 2 2 2 1 Tropomyosin DUF3552 PF12072.8 AIM22383.1 - 0.00026 20.5 3.2 0.00041 19.8 3.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) ATG16 PF08614.11 AIM22383.1 - 0.00048 20.4 8.2 0.00048 20.4 8.2 1.6 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) XhlA PF10779.9 AIM22383.1 - 0.00067 19.8 11.2 0.13 12.5 1.3 4.1 2 1 2 4 4 4 1 Haemolysin XhlA Spc7 PF08317.11 AIM22383.1 - 0.0025 16.8 7.0 0.0025 16.8 7.0 1.5 2 0 0 2 2 2 1 Spc7 kinetochore protein DUF812 PF05667.11 AIM22383.1 - 0.012 14.6 5.8 0.018 14.0 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) ABC_tran_CTD PF16326.5 AIM22383.1 - 0.012 15.9 9.8 2.7 8.3 0.3 3.8 2 1 1 3 3 3 0 ABC transporter C-terminal domain Tropomyosin_1 PF12718.7 AIM22383.1 - 0.023 14.9 9.9 6.7 6.9 0.0 2.5 1 1 1 2 2 2 0 Tropomyosin like FPP PF05911.11 AIM22383.1 - 0.033 12.4 5.2 0.048 11.8 5.2 1.2 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil DUF724 PF05266.14 AIM22383.1 - 0.11 12.4 2.1 0.19 11.6 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF4941 PF16299.5 AIM22383.1 - 0.15 11.4 0.0 0.41 9.9 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4941) TTKRSYEDQ PF10212.9 AIM22383.1 - 0.17 10.9 5.9 0.28 10.1 5.9 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein MscS_porin PF12795.7 AIM22383.1 - 0.19 11.3 19.4 0.021 14.4 13.7 2.0 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain Fib_alpha PF08702.10 AIM22383.1 - 0.26 11.5 5.2 0.96 9.6 3.2 2.6 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 AIM22383.1 - 0.26 11.3 14.4 0.28 11.2 12.8 1.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus BBP1_C PF15272.6 AIM22383.1 - 0.32 10.8 2.2 0.6 9.9 2.1 1.5 1 1 0 1 1 1 0 Spindle pole body component BBP1, C-terminal AAA_13 PF13166.6 AIM22383.1 - 0.32 9.6 8.0 0.51 8.9 8.0 1.3 1 0 0 1 1 1 0 AAA domain Prefoldin_2 PF01920.20 AIM22383.1 - 0.34 10.9 4.9 7.2 6.6 0.1 3.3 2 1 0 3 3 3 0 Prefoldin subunit DUF4472 PF14739.6 AIM22383.1 - 0.4 11.4 7.0 0.26 12.1 0.3 2.6 2 1 1 3 3 2 0 Domain of unknown function (DUF4472) FlaC_arch PF05377.11 AIM22383.1 - 0.45 10.9 2.4 10 6.6 0.1 3.3 1 1 2 4 4 4 0 Flagella accessory protein C (FlaC) FAM76 PF16046.5 AIM22383.1 - 0.47 9.8 5.7 1.7 7.9 5.7 1.9 1 1 0 1 1 1 0 FAM76 protein ADIP PF11559.8 AIM22383.1 - 0.47 10.5 14.7 0.044 13.9 1.4 2.6 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding SlyX PF04102.12 AIM22383.1 - 0.56 10.9 9.8 8.8 7.0 0.1 3.5 2 1 2 4 4 4 0 SlyX BRE1 PF08647.11 AIM22383.1 - 0.71 10.0 4.8 0.25 11.4 0.2 2.4 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase DUF2730 PF10805.8 AIM22383.1 - 0.9 9.7 5.9 4.5 7.4 0.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) Filament PF00038.21 AIM22383.1 - 1.3 8.5 10.5 3 7.4 7.7 2.3 2 1 1 3 3 3 0 Intermediate filament protein DUF16 PF01519.16 AIM22383.1 - 1.5 9.4 6.7 68 4.0 5.2 3.1 2 1 0 2 2 1 0 Protein of unknown function DUF16 RseA_C PF03873.13 AIM22383.1 - 2.7 8.3 5.9 34 4.8 0.7 3.7 3 1 0 3 3 3 0 Anti sigma-E protein RseA, C-terminal domain Phage_GP20 PF06810.11 AIM22383.1 - 4.8 7.0 8.8 0.33 10.7 0.1 2.5 2 1 1 3 3 2 0 Phage minor structural protein GP20 Phage_stabilise PF11134.8 AIM22384.1 - 3.6e-197 655.9 0.3 4e-197 655.7 0.3 1.0 1 0 0 1 1 1 1 Phage stabilisation protein P22_Tail-4 PF11650.8 AIM22385.1 - 5.2e-72 241.2 0.0 5.8e-72 241.0 0.0 1.0 1 0 0 1 1 1 1 P22 tail accessory factor DUF3372 PF11852.8 AIM22385.1 - 0.021 14.3 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3372) P22_CoatProtein PF11651.8 AIM22387.1 - 4.7e-157 522.9 5.7 5.3e-157 522.7 5.7 1.0 1 0 0 1 1 1 1 P22 coat protein - gene protein 5 Phage-scaffold PF09306.10 AIM22388.1 - 3.4e-08 33.2 13.2 4.4e-08 32.8 13.2 1.2 1 0 0 1 1 1 1 Bacteriophage, scaffolding protein P22_portal PF16510.5 AIM22389.1 - 1.6e-272 906.0 12.3 2e-272 905.7 12.3 1.0 1 0 0 1 1 1 1 Phage P22-like portal protein Terminase_6C PF17289.2 AIM22390.1 - 7.5e-17 61.8 0.0 2.7e-16 60.1 0.0 1.8 2 0 0 2 2 2 1 Terminase RNaseH-like domain Terminase_6 PF03237.15 AIM22390.1 - 3.9e-14 52.8 0.0 6e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Terminase-like family DUF1564 PF07600.11 AIM22391.1 - 0.041 13.6 0.1 0.063 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) HTH_7 PF02796.15 AIM22391.1 - 0.047 13.8 0.0 0.23 11.6 0.0 2.3 2 1 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_28 PF13518.6 AIM22391.1 - 0.075 13.2 0.1 0.33 11.1 0.0 2.1 2 1 0 2 2 2 0 Helix-turn-helix domain DndB PF14072.6 AIM22391.1 - 0.075 12.2 0.0 0.085 12.1 0.0 1.1 1 0 0 1 1 1 0 DNA-sulfur modification-associated DUF1737 PF08410.10 AIM22392.1 - 0.00041 20.2 0.0 0.00064 19.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1737) DUF555 PF04475.12 AIM22393.1 - 0.092 13.1 0.1 0.098 13.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF555) DUF2560 PF10834.8 AIM22394.1 - 2e-25 88.8 1.3 2.5e-25 88.5 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2560) Phage_lysis PF03245.13 AIM22395.1 - 3.4e-33 114.5 7.7 4.2e-33 114.2 7.7 1.1 1 0 0 1 1 1 1 Bacteriophage Rz lysis protein Atypical_Card PF18461.1 AIM22395.1 - 0.0039 17.4 0.4 0.1 12.8 0.3 2.1 2 0 0 2 2 2 1 Atypical caspase recruitment domain KELK PF15796.5 AIM22395.1 - 0.0067 16.9 7.3 0.012 16.0 6.1 1.8 2 0 0 2 2 2 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF1664 PF07889.12 AIM22395.1 - 0.012 15.7 2.7 0.013 15.5 1.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) HALZ PF02183.18 AIM22395.1 - 0.035 14.3 2.1 0.035 14.3 2.1 1.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper NHase_beta PF02211.15 AIM22395.1 - 0.13 12.3 0.0 0.15 12.1 0.0 1.1 1 0 0 1 1 1 0 Nitrile hydratase beta subunit TMF_DNA_bd PF12329.8 AIM22395.1 - 0.13 12.3 8.1 0.27 11.3 6.6 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Jnk-SapK_ap_N PF09744.9 AIM22395.1 - 0.13 12.4 6.0 0.2 11.9 5.5 1.3 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 LapA_dom PF06305.11 AIM22395.1 - 0.39 10.6 3.3 2.7 7.9 0.3 2.9 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Phage_lysozyme PF00959.19 AIM22396.1 - 8.9e-24 84.0 0.0 1.1e-23 83.8 0.0 1.1 1 0 0 1 1 1 1 Phage lysozyme Phage_holin_3_1 PF05106.12 AIM22397.1 - 1.6e-31 108.7 0.1 1.7e-31 108.5 0.1 1.0 1 0 0 1 1 1 1 Phage holin family (Lysis protein S) DUF3792 PF12670.7 AIM22397.1 - 0.016 15.4 1.5 0.031 14.5 1.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3792) Phage_holin_3_3 PF16083.5 AIM22397.1 - 0.13 12.4 3.3 0.39 10.9 3.4 1.7 1 1 1 2 2 2 0 LydA holin phage, holin superfamily III Phage_antitermQ PF06530.12 AIM22399.1 - 3.5e-24 85.0 0.0 4.7e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Phage antitermination protein Q DUF1133 PF06576.11 AIM22399.1 - 2.1e-09 37.0 4.0 2.1e-06 27.3 0.1 2.9 1 1 1 2 2 2 2 Protein of unknown function (DUF1133) DUF1036 PF06282.11 AIM22399.1 - 0.073 13.6 0.1 0.9 10.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1036) NinG PF05766.12 AIM22400.1 - 3.9e-70 235.6 10.6 4.4e-70 235.4 10.6 1.0 1 0 0 1 1 1 1 Bacteriophage Lambda NinG protein Med10 PF09748.9 AIM22400.1 - 0.026 14.5 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex Lar_restr_allev PF14354.6 AIM22400.1 - 0.041 14.3 2.4 0.041 14.3 2.4 2.8 2 1 0 2 2 2 0 Restriction alleviation protein Lar ADD_DNMT3 PF17980.1 AIM22400.1 - 5.5 7.1 7.9 5.3 7.1 0.1 3.1 3 0 0 3 3 3 0 Cysteine rich ADD domain in DNMT3 Eapp_C PF10238.9 AIM22400.1 - 8.4 6.5 11.4 62 3.6 10.2 2.1 1 1 1 2 2 2 0 E2F-associated phosphoprotein FYDLN_acid PF09538.10 AIM22400.1 - 8.6 7.1 7.2 7.3 7.3 5.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) DUF2591 PF10765.9 AIM22401.1 - 9.6e-05 22.6 0.0 0.00012 22.3 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2591) NinE PF05322.11 AIM22403.1 - 3.5e-10 39.6 1.3 4.3e-10 39.3 1.3 1.1 1 0 0 1 1 1 1 NINE Protein NinB PF05772.12 AIM22404.1 - 1.6e-52 176.7 0.0 1.9e-52 176.5 0.0 1.0 1 0 0 1 1 1 1 NinB protein DnaB_C PF03796.15 AIM22406.1 - 2.9e-64 216.8 0.0 7.9e-64 215.4 0.0 1.6 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain DnaB PF00772.21 AIM22406.1 - 1.7e-11 44.1 0.0 3.6e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 DnaB-like helicase N terminal domain ATPase PF06745.13 AIM22406.1 - 7.6e-08 32.0 0.1 1.4e-07 31.2 0.1 1.5 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 AIM22406.1 - 2.3e-07 30.6 0.0 5.5e-07 29.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 AIM22406.1 - 0.0014 18.0 0.3 0.0027 17.0 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 AIM22406.1 - 0.0022 18.4 0.0 0.0056 17.1 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) GvpD PF07088.11 AIM22406.1 - 0.0034 16.1 0.0 0.0049 15.5 0.0 1.2 1 0 0 1 1 1 1 GvpD gas vesicle protein NACHT PF05729.12 AIM22406.1 - 0.013 15.4 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain TIP49 PF06068.13 AIM22406.1 - 0.014 14.6 0.1 0.05 12.8 0.0 1.8 2 0 0 2 2 2 0 TIP49 P-loop domain RuvB_N PF05496.12 AIM22406.1 - 0.02 14.7 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 AIM22406.1 - 0.023 14.0 0.0 0.045 13.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.17 AIM22406.1 - 0.036 13.8 0.0 0.077 12.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Chromo_shadow PF01393.19 AIM22406.1 - 0.073 13.2 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Chromo shadow domain AAA_18 PF13238.6 AIM22406.1 - 0.098 13.2 0.0 0.26 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AIM22406.1 - 0.15 12.6 0.1 1.5 9.3 0.0 2.2 2 0 0 2 2 2 0 ABC transporter Phage_rep_O PF04492.13 AIM22407.1 - 5.5e-37 126.2 0.6 9.7e-37 125.5 0.6 1.4 1 0 0 1 1 1 1 Bacteriophage replication protein O HTH_Crp_2 PF13545.6 AIM22407.1 - 0.065 13.2 0.2 0.14 12.2 0.2 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Phage_CII PF05269.11 AIM22408.1 - 2.5e-29 101.3 0.1 2.6e-29 101.3 0.1 1.0 1 0 0 1 1 1 1 Bacteriophage CII protein HTH_23 PF13384.6 AIM22408.1 - 0.0014 18.4 0.1 0.023 14.5 0.0 2.1 1 1 1 2 2 2 1 Homeodomain-like domain DUF3243 PF11588.8 AIM22408.1 - 0.009 16.3 0.1 0.018 15.3 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3243) HTH_28 PF13518.6 AIM22408.1 - 0.017 15.2 0.0 0.037 14.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain TTRAP PF14203.6 AIM22408.1 - 0.057 13.4 0.1 0.092 12.7 0.1 1.3 1 0 0 1 1 1 0 Putative tranposon-transfer assisting protein HTH_Tnp_1 PF01527.20 AIM22408.1 - 0.061 13.6 0.1 0.12 12.8 0.1 1.5 1 1 0 1 1 1 0 Transposase DELLA PF12041.8 AIM22408.1 - 0.084 12.8 0.1 1.8 8.5 0.0 2.2 1 1 1 2 2 2 0 Transcriptional regulator DELLA protein N terminal P22_Cro PF14549.6 AIM22408.1 - 0.13 12.1 0.4 0.24 11.3 0.1 1.5 1 1 0 1 1 1 0 DNA-binding transcriptional regulator Cro YdaS_antitoxin PF15943.5 AIM22409.1 - 1.3e-23 82.6 0.0 1.4e-23 82.5 0.0 1.0 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT P22_Cro PF14549.6 AIM22409.1 - 2.2e-05 24.2 0.0 2.8e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 DNA-binding transcriptional regulator Cro Cro PF09048.10 AIM22409.1 - 0.026 14.6 0.6 0.25 11.4 0.0 2.4 1 1 1 2 2 2 0 Cro DUF4427 PF14468.6 AIM22409.1 - 0.026 14.6 0.0 0.027 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4427) HTH_Tnp_1_2 PF13022.6 AIM22409.1 - 0.084 13.0 0.0 0.097 12.8 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase HTH_31 PF13560.6 AIM22409.1 - 0.1 13.0 0.0 0.15 12.5 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_3 PF01381.22 AIM22410.1 - 5.5e-08 32.8 0.0 1e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 AIM22410.1 - 1.3e-05 25.4 0.1 2.2e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 AIM22410.1 - 2.5e-05 24.6 0.0 9.4e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Cro/C1-type HTH DNA-binding domain HTH_19 PF12844.7 AIM22410.1 - 3.1e-05 23.9 0.0 4.6e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain YdaS_antitoxin PF15943.5 AIM22410.1 - 0.00034 20.4 0.3 0.00082 19.2 0.3 1.6 1 1 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Phage_CI_repr PF07022.13 AIM22410.1 - 0.00035 20.6 0.0 0.00056 19.9 0.0 1.3 1 0 0 1 1 1 1 Bacteriophage CI repressor helix-turn-helix domain HTH_37 PF13744.6 AIM22410.1 - 0.017 15.1 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Peptidase_S24 PF00717.23 AIM22410.1 - 0.017 15.0 0.1 0.027 14.4 0.1 1.3 1 0 0 1 1 1 0 Peptidase S24-like HTH_24 PF13412.6 AIM22410.1 - 0.049 13.2 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_1 PF00126.27 AIM22410.1 - 0.07 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family SpvB PF03534.13 AIM22412.1 - 0.016 14.4 0.0 0.016 14.4 0.0 1.1 1 0 0 1 1 1 0 Salmonella virulence plasmid 65kDa B protein ERF PF04404.12 AIM22413.1 - 4.7e-11 42.8 0.0 5.1e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 ERF superfamily DUF4882 PF16223.5 AIM22413.1 - 0.094 11.9 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4882) DUF3235 PF11574.8 AIM22413.1 - 0.097 13.5 0.0 0.17 12.7 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3235) DUF2002 PF09400.10 AIM22413.1 - 0.1 12.6 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2002) HTH_Tnp_1 PF01527.20 AIM22414.1 - 4.5e-12 46.1 0.3 5.6e-12 45.8 0.3 1.2 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 AIM22414.1 - 8.7e-07 28.6 0.0 4.1e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 AIM22414.1 - 1.9e-06 27.9 0.0 2.9e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_1 PF00126.27 AIM22414.1 - 0.00089 19.2 0.4 0.0018 18.2 0.0 1.8 2 1 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_3 PF01381.22 AIM22414.1 - 0.0014 18.6 0.9 0.0065 16.5 0.0 2.3 2 1 0 2 2 2 1 Helix-turn-helix P22_Cro PF14549.6 AIM22414.1 - 0.0093 15.8 0.1 0.014 15.2 0.1 1.3 1 0 0 1 1 1 1 DNA-binding transcriptional regulator Cro HTH_29 PF13551.6 AIM22414.1 - 0.028 14.4 0.0 0.048 13.7 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix Trp_repressor PF01371.19 AIM22414.1 - 0.029 14.5 0.2 0.093 12.9 0.0 1.7 2 0 0 2 2 2 0 Trp repressor protein HTH_31 PF13560.6 AIM22414.1 - 0.055 13.8 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain LapA_dom PF06305.11 AIM22414.1 - 1.3 8.9 3.3 1.9 8.4 3.3 1.4 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain rve PF00665.26 AIM22415.1 - 2.3e-31 108.5 0.2 3e-31 108.1 0.2 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 AIM22415.1 - 2e-12 46.7 0.1 3.2e-12 46.0 0.1 1.3 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 AIM22415.1 - 3.8e-07 30.4 0.0 5e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 DDE domain rve_2 PF13333.6 AIM22415.1 - 7.5e-05 22.8 0.4 0.00017 21.7 0.1 1.7 2 0 0 2 2 2 1 Integrase core domain ERF PF04404.12 AIM22416.1 - 3.9e-07 30.0 1.1 5.2e-07 29.6 1.1 1.4 1 1 0 1 1 1 1 ERF superfamily SSB PF00436.25 AIM22417.1 - 6.6e-41 138.6 1.0 8.3e-41 138.2 1.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family tRNA_anti-codon PF01336.25 AIM22417.1 - 0.14 12.1 0.2 0.27 11.2 0.3 1.6 1 1 0 1 1 1 0 OB-fold nucleic acid binding domain LT-IIB PF06453.11 AIM22418.1 - 0.05 13.5 0.0 0.056 13.3 0.0 1.1 1 0 0 1 1 1 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) HALZ PF02183.18 AIM22419.1 - 0.024 14.8 0.0 0.05 13.8 0.0 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Phage_Nu1 PF07471.12 AIM22419.1 - 0.06 13.1 1.5 0.07 12.9 1.5 1.2 1 0 0 1 1 1 0 Phage DNA packaging protein Nu1 Jnk-SapK_ap_N PF09744.9 AIM22424.1 - 0.015 15.6 9.1 0.021 15.1 9.1 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 XhlA PF10779.9 AIM22424.1 - 0.015 15.5 0.8 0.029 14.6 0.8 1.5 1 0 0 1 1 1 0 Haemolysin XhlA Troponin PF00992.20 AIM22424.1 - 0.096 13.0 7.3 0.12 12.6 5.8 1.8 1 1 1 2 2 2 0 Troponin Shugoshin_N PF07558.11 AIM22424.1 - 0.28 11.1 5.1 0.11 12.4 1.2 2.2 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region MRPL52 PF18699.1 AIM22424.1 - 0.42 10.8 4.8 0.54 10.5 3.5 1.9 2 0 0 2 2 2 0 Mitoribosomal protein mL52 TMPIT PF07851.13 AIM22424.1 - 0.6 9.3 2.7 0.72 9.1 2.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein 5_nucleotid PF05761.14 AIM22424.1 - 0.76 8.6 2.6 0.89 8.4 2.6 1.2 1 0 0 1 1 1 0 5' nucleotidase family bZIP_1 PF00170.21 AIM22424.1 - 2.6 8.2 8.8 4.2 7.5 0.8 2.5 1 1 1 2 2 2 0 bZIP transcription factor DNA_pol3_theta PF06440.11 AIM22428.1 - 1.4e-34 117.5 0.3 1.7e-34 117.3 0.3 1.1 1 0 0 1 1 1 1 DNA polymerase III, theta subunit HHV-5_US34A PF17087.5 AIM22428.1 - 0.07 13.3 0.2 0.099 12.8 0.2 1.4 1 0 0 1 1 1 0 Herpesvirus US34A protein family DUF2116 PF09889.9 AIM22430.1 - 0.027 14.4 0.4 0.041 13.9 0.4 1.3 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF1233 PF06806.12 AIM22432.1 - 3e-34 116.4 0.0 3.5e-34 116.2 0.0 1.1 1 0 0 1 1 1 1 Putative excisionase (DUF1233) Arm-DNA-bind_2 PF12167.8 AIM22433.1 - 3.6e-23 81.3 0.0 1.5e-22 79.3 0.0 2.1 3 0 0 3 3 3 1 Arm DNA-binding domain Phage_integrase PF00589.22 AIM22433.1 - 7.9e-20 71.3 0.1 1.4e-19 70.6 0.1 1.3 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_5 PF13102.6 AIM22433.1 - 0.072 13.4 0.0 0.27 11.6 0.0 2.0 1 1 1 2 2 2 0 Phage integrase SAM-like domain FliE PF02049.18 AIM22434.1 - 8e-29 99.6 3.7 9.9e-29 99.3 3.7 1.2 1 0 0 1 1 1 1 Flagellar hook-basal body complex protein FliE YscJ_FliF PF01514.17 AIM22435.1 - 1.6e-76 256.3 0.1 1e-75 253.7 0.0 2.3 2 0 0 2 2 2 1 Secretory protein of YscJ/FliF family YscJ_FliF_C PF08345.11 AIM22435.1 - 1.7e-51 174.5 7.0 1.7e-51 174.5 7.0 2.0 2 0 0 2 2 2 1 Flagellar M-ring protein C-terminal FliG_C PF01706.16 AIM22436.1 - 1.9e-40 137.4 12.9 7.5e-37 125.8 4.5 3.7 2 1 2 4 4 4 3 FliG C-terminal domain FliG_N PF14842.6 AIM22436.1 - 2.3e-34 118.0 15.1 4.4e-30 104.3 1.8 3.7 2 1 2 4 4 4 2 FliG N-terminal domain FliG_M PF14841.6 AIM22436.1 - 4.9e-30 103.6 5.4 1.4e-24 86.1 0.1 4.1 4 0 0 4 4 4 2 FliG middle domain MgtE_N PF03448.17 AIM22436.1 - 3.8e-07 30.7 17.4 0.15 12.7 0.4 5.3 2 2 3 5 5 5 4 MgtE intracellular N domain DUF3654 PF12376.8 AIM22436.1 - 0.0014 18.9 0.4 0.0029 17.8 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3654) PSK_trans_fac PF07704.11 AIM22436.1 - 0.43 11.4 3.4 0.78 10.5 0.8 2.8 2 1 0 2 2 2 0 Rv0623-like transcription factor PhoU PF01895.19 AIM22436.1 - 3.1 8.3 7.7 0.8 10.2 2.4 2.8 2 2 1 3 3 3 0 PhoU domain FliH PF02108.16 AIM22437.1 - 2.3e-18 66.5 1.3 2.5e-18 66.4 0.0 1.6 2 0 0 2 2 2 1 Flagellar assembly protein FliH Yae1_N PF09811.9 AIM22437.1 - 0.0077 15.9 11.7 0.014 15.1 11.7 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal DUF3294 PF07957.11 AIM22437.1 - 0.16 11.7 0.2 0.28 10.9 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3294) Activator_LAG-3 PF11498.8 AIM22437.1 - 4.6 6.1 15.8 7 5.5 15.8 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 ATP-synt_ab PF00006.25 AIM22438.1 - 1.8e-70 236.9 0.0 2.3e-70 236.6 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain T3SS_ATPase_C PF18269.1 AIM22438.1 - 8.3e-26 89.7 0.7 1.6e-25 88.7 0.7 1.5 1 0 0 1 1 1 1 T3SS EscN ATPase C-terminal domain ATP-synt_ab_N PF02874.23 AIM22438.1 - 0.062 13.8 0.2 0.16 12.5 0.2 1.8 1 0 0 1 1 1 0 ATP synthase alpha/beta family, beta-barrel domain ABC_tran PF00005.27 AIM22438.1 - 0.062 13.8 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter DUF4174 PF13778.6 AIM22438.1 - 0.16 12.4 0.0 0.34 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) FliJ PF02050.16 AIM22439.1 - 8e-36 123.0 28.7 9.2e-36 122.8 28.7 1.0 1 0 0 1 1 1 1 Flagellar FliJ protein DUF3847 PF12958.7 AIM22439.1 - 0.033 14.3 0.4 0.033 14.3 0.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3847) ComC PF03047.14 AIM22439.1 - 0.043 13.6 0.2 0.1 12.4 0.2 1.7 1 0 0 1 1 1 0 COMC family CSN5_C PF18323.1 AIM22439.1 - 0.075 14.0 10.8 0.2 12.6 1.2 2.1 1 1 1 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain SNARE PF05739.19 AIM22439.1 - 0.14 12.2 5.7 0.8 9.8 2.2 2.7 1 1 1 2 2 2 0 SNARE domain Ribosomal_L22 PF00237.19 AIM22439.1 - 0.15 12.3 3.3 4.6 7.5 0.1 2.2 2 0 0 2 2 2 0 Ribosomal protein L22p/L17e YscO-like PF16789.5 AIM22439.1 - 0.31 11.1 11.9 0.93 9.5 11.9 1.7 1 1 0 1 1 1 0 YscO-like protein Exonuc_VII_L PF02601.15 AIM22439.1 - 0.48 9.9 15.4 0.62 9.6 15.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Sulfatase_C PF14707.6 AIM22439.1 - 0.7 10.6 4.9 2.1 9.1 0.2 2.4 1 1 1 2 2 2 0 C-terminal region of aryl-sulfatase Muted PF14942.6 AIM22439.1 - 0.94 9.8 17.4 1.1 9.5 2.9 2.0 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein OEP PF02321.18 AIM22439.1 - 9.2 6.0 26.0 1.3 8.8 11.4 2.1 1 1 1 2 2 2 0 Outer membrane efflux protein FliL PF03748.14 AIM22440.1 - 5.6e-22 78.3 0.0 6.9e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 Flagellar basal body-associated protein FliL FliM PF02154.15 AIM22441.1 - 3.8e-74 248.7 0.0 5.1e-74 248.3 0.0 1.2 1 0 0 1 1 1 1 Flagellar motor switch protein FliM FliMN_C PF01052.20 AIM22441.1 - 3.1e-15 55.9 0.0 5.7e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 Type III flagellar switch regulator (C-ring) FliN C-term FliMN_C PF01052.20 AIM22442.1 - 1.9e-25 88.6 1.7 2.4e-25 88.3 1.7 1.1 1 0 0 1 1 1 1 Type III flagellar switch regulator (C-ring) FliN C-term FliN_N PF16973.5 AIM22442.1 - 4.7e-24 84.0 3.5 6.8e-24 83.5 3.5 1.2 1 0 0 1 1 1 1 Flagellar motor switch protein FliN N-terminal p450 PF00067.22 AIM22442.1 - 0.036 12.8 0.0 0.042 12.6 0.0 1.1 1 0 0 1 1 1 0 Cytochrome P450 FliO PF04347.13 AIM22443.1 - 3.1e-22 78.7 0.1 4.4e-22 78.2 0.1 1.2 1 0 0 1 1 1 1 Flagellar biosynthesis protein, FliO FliP PF00813.20 AIM22444.1 - 1.8e-78 262.8 10.8 2.2e-78 262.5 10.8 1.1 1 0 0 1 1 1 1 FliP family Bac_export_3 PF01313.19 AIM22445.1 - 2.7e-30 104.1 8.3 3.1e-30 103.9 8.3 1.1 1 0 0 1 1 1 1 Bacterial export proteins, family 3 Bac_export_1 PF01311.20 AIM22445.1 - 0.00011 21.9 8.1 0.00013 21.6 8.1 1.0 1 0 0 1 1 1 1 Bacterial export proteins, family 1 DUF5455 PF17537.2 AIM22445.1 - 0.07 13.6 6.6 0.089 13.2 6.4 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5455) Syndecan PF01034.20 AIM22445.1 - 0.87 9.5 3.0 0.67 9.9 0.4 1.9 2 0 0 2 2 2 0 Syndecan domain Bac_export_2 PF01312.19 AIM22445.1 - 2.2 7.4 6.7 4.8 6.3 2.5 1.9 1 1 1 2 2 2 0 FlhB HrpN YscU SpaS Family Bac_export_1 PF01311.20 AIM22446.1 - 6.9e-67 225.4 30.2 7.9e-67 225.2 30.2 1.0 1 0 0 1 1 1 1 Bacterial export proteins, family 1 TMC PF07810.13 AIM22446.1 - 0.12 13.0 0.1 0.12 13.0 0.1 2.4 2 1 1 3 3 3 0 TMC domain Ribosomal_S22 PF08136.11 AIM22447.1 - 0.0018 18.6 0.2 0.0022 18.3 0.2 1.4 1 1 0 1 1 1 1 30S ribosomal protein subunit S22 family DUF1970 PF09301.10 AIM22449.1 - 0.11 12.8 0.5 0.14 12.4 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1970) Flagellin_N PF00669.20 AIM22450.1 - 3.7e-23 82.2 10.6 3.7e-23 82.2 10.6 2.3 2 1 0 2 2 2 1 Bacterial flagellin N-terminal helical region Flagellin_C PF00700.21 AIM22450.1 - 0.0061 16.9 4.1 0.0061 16.9 4.1 2.8 2 0 0 2 2 2 1 Bacterial flagellin C-terminal helical region DUF1664 PF07889.12 AIM22450.1 - 0.017 15.1 0.6 0.017 15.1 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FIVAR PF07554.13 AIM22450.1 - 0.14 12.9 0.8 0.14 12.9 0.8 3.1 3 1 0 3 3 3 0 FIVAR domain DUF1542 PF07564.11 AIM22450.1 - 0.16 12.1 2.0 0.23 11.6 0.2 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) Flg_bbr_C PF06429.13 AIM22451.1 - 1.7e-09 37.6 2.3 7.6e-09 35.6 2.3 2.2 1 0 0 1 1 1 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 AIM22451.1 - 2.2e-09 37.1 8.0 8e-09 35.2 8.0 2.0 1 0 0 1 1 1 1 Flagella basal body rod protein DUF4200 PF13863.6 AIM22451.1 - 0.038 14.4 0.0 0.097 13.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF5082 PF16888.5 AIM22451.1 - 0.048 13.9 2.7 0.24 11.7 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) Spc7 PF08317.11 AIM22451.1 - 0.093 11.6 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DivIC PF04977.15 AIM22451.1 - 0.098 12.4 0.2 0.32 10.8 0.2 1.9 1 0 0 1 1 1 0 Septum formation initiator GPAT_N PF14829.6 AIM22451.1 - 0.12 12.4 0.0 0.36 10.8 0.0 1.8 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal Phage_Mu_Gam PF07352.12 AIM22451.1 - 0.14 12.1 0.1 23 4.9 0.0 2.6 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein Glucosaminidase PF01832.20 AIM22452.1 - 1.3e-20 73.6 0.1 3.1e-20 72.5 0.1 1.6 1 0 0 1 1 1 1 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase Rod-binding PF10135.9 AIM22452.1 - 5.2e-17 62.2 6.7 5.2e-17 62.2 6.7 2.1 2 0 0 2 2 2 1 Rod binding protein FlgI PF02119.16 AIM22453.1 - 1.8e-136 454.6 16.5 2.1e-136 454.4 16.5 1.0 1 0 0 1 1 1 1 Flagellar P-ring protein FlgH PF02107.16 AIM22454.1 - 7.9e-60 201.3 0.4 9.3e-60 201.1 0.4 1.0 1 0 0 1 1 1 1 Flagellar L-ring protein Flg_bbr_C PF06429.13 AIM22455.1 - 5.9e-27 93.6 3.2 1.4e-26 92.4 2.0 2.3 2 0 0 2 2 2 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 AIM22455.1 - 2.9e-14 52.6 1.2 9.4e-14 51.0 1.2 2.0 1 0 0 1 1 1 1 Flagella basal body rod protein Acetyltransf_19 PF18015.1 AIM22455.1 - 0.054 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Flg_bbr_C PF06429.13 AIM22456.1 - 1.5e-21 76.3 0.5 4.3e-21 74.8 0.5 1.8 1 0 0 1 1 1 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 AIM22456.1 - 1.4e-09 37.7 1.3 1.4e-09 37.7 1.3 2.8 3 0 0 3 3 3 1 Flagella basal body rod protein Flg_bbr_C PF06429.13 AIM22457.1 - 1.1e-22 79.9 0.5 7.1e-22 77.3 0.5 2.5 1 0 0 1 1 1 1 Flagellar basal body rod FlgEFG protein C-terminal FlaE PF07559.14 AIM22457.1 - 1.9e-22 80.1 8.8 1.9e-22 80.1 8.8 2.4 3 0 0 3 3 3 1 Flagellar basal body protein FlaE Flg_bb_rod PF00460.20 AIM22457.1 - 1.5e-11 44.0 5.2 4.6e-11 42.4 5.2 1.9 1 0 0 1 1 1 1 Flagella basal body rod protein FlgD PF03963.14 AIM22458.1 - 8.9e-23 80.4 6.6 1.6e-22 79.6 6.6 1.4 1 0 0 1 1 1 1 Flagellar hook capping protein - N-terminal region FlgD_ig PF13860.6 AIM22458.1 - 1e-22 79.8 1.7 2.1e-22 78.7 1.7 1.6 1 0 0 1 1 1 1 FlgD Ig-like domain FLgD_tudor PF13861.6 AIM22458.1 - 2.4e-15 56.5 0.0 6e-15 55.2 0.0 1.7 1 1 0 1 1 1 1 FlgD Tudor-like domain MG2 PF01835.19 AIM22458.1 - 0.041 14.3 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 MG2 domain DUF2271 PF10029.9 AIM22458.1 - 0.12 12.0 0.0 0.88 9.2 0.0 2.0 1 1 1 2 2 2 0 Predicted periplasmic protein (DUF2271) Flg_bbr_C PF06429.13 AIM22459.1 - 2.5e-12 46.8 2.1 2.5e-12 46.8 2.1 1.8 2 1 0 2 2 2 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 AIM22459.1 - 1.4e-08 34.5 0.7 1.4e-08 34.5 0.7 1.9 2 0 0 2 2 2 1 Flagella basal body rod protein Flg_bb_rod PF00460.20 AIM22460.1 - 1.4e-12 47.3 0.2 3.1e-12 46.2 0.2 1.6 1 0 0 1 1 1 1 Flagella basal body rod protein ChapFlgA PF13144.6 AIM22461.1 - 1.5e-29 102.5 0.0 2.9e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 Chaperone for flagella basal body P-ring formation SAF PF08666.12 AIM22461.1 - 6.8e-13 49.0 0.0 5.6e-12 46.1 0.0 2.3 2 0 0 2 2 2 1 SAF domain ChapFlgA_N PF17656.1 AIM22461.1 - 9.9e-09 35.3 0.1 2.3e-08 34.1 0.1 1.6 1 0 0 1 1 1 1 FlgA N-terminal domain DUF2190 PF09956.9 AIM22461.1 - 0.02 15.4 0.7 0.098 13.1 0.4 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2190) FlgM PF04316.13 AIM22462.1 - 4.3e-11 43.0 1.2 6.3e-11 42.5 1.2 1.3 1 0 0 1 1 1 1 Anti-sigma-28 factor, FlgM FlgN PF05130.12 AIM22463.1 - 2.9e-24 86.2 6.9 3.3e-24 86.1 6.9 1.0 1 0 0 1 1 1 1 FlgN protein RelE PF06296.12 AIM22464.1 - 5.5e-38 129.8 0.2 6.2e-38 129.6 0.2 1.0 1 0 0 1 1 1 1 RelE toxin of RelE / RelB toxin-antitoxin system HTH_3 PF01381.22 AIM22465.1 - 3.6e-07 30.1 0.1 5.1e-07 29.6 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 AIM22465.1 - 3.4e-05 24.1 0.1 5e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain MqsA_antitoxin PF15731.5 AIM22465.1 - 9.7e-05 22.5 0.0 0.00012 22.2 0.0 1.1 1 0 0 1 1 1 1 Antitoxin component of bacterial toxin-antitoxin system, MqsA YdaS_antitoxin PF15943.5 AIM22465.1 - 0.062 13.2 0.0 0.091 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT P22_Cro PF14549.6 AIM22465.1 - 0.088 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro DUF4447 PF14590.6 AIM22465.1 - 0.088 12.6 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4447) BrkDBD PF09607.10 AIM22465.1 - 0.11 12.3 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Brinker DNA-binding domain FlhE PF06366.13 AIM22466.1 - 1.7e-34 118.0 0.0 2e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 Flagellar protein FlhE FHIPEP PF00771.20 AIM22467.1 - 1.1e-267 889.8 2.6 1.3e-267 889.6 2.6 1.0 1 0 0 1 1 1 1 FHIPEP family DUF4896 PF16237.5 AIM22467.1 - 0.01 15.7 3.5 0.01 15.7 3.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4896) Bac_export_2 PF01312.19 AIM22468.1 - 1.8e-126 421.8 0.7 2.1e-126 421.6 0.7 1.0 1 0 0 1 1 1 1 FlhB HrpN YscU SpaS Family Thymidylat_synt PF00303.19 AIM22468.1 - 0.033 13.3 0.0 0.044 12.9 0.0 1.3 1 0 0 1 1 1 0 Thymidylate synthase CheZ PF04344.13 AIM22469.1 - 1.6e-76 256.7 2.5 1.8e-76 256.6 2.5 1.0 1 0 0 1 1 1 1 Chemotaxis phosphatase, CheZ Arabinose_bd PF12625.7 AIM22469.1 - 0.0054 16.8 0.4 0.0081 16.3 0.4 1.2 1 0 0 1 1 1 1 Arabinose-binding domain of AraC transcription regulator, N-term Lipoprotein_20 PF13942.6 AIM22469.1 - 0.0073 16.2 0.1 0.02 14.8 0.1 1.6 1 1 1 2 2 2 1 YfhG lipoprotein Dynamin_M PF01031.20 AIM22469.1 - 0.0086 15.3 0.0 0.011 15.0 0.0 1.0 1 0 0 1 1 1 1 Dynamin central region Response_reg PF00072.24 AIM22470.1 - 2.1e-32 111.6 0.0 2.4e-32 111.4 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain SBP_bac_3 PF00497.20 AIM22470.1 - 0.011 15.1 0.4 1.6 8.1 0.0 2.0 1 1 1 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 OpuAC PF04069.12 AIM22470.1 - 0.028 14.0 0.0 0.041 13.5 0.0 1.3 1 1 0 1 1 1 0 Substrate binding domain of ABC-type glycine betaine transport system BRCT_3 PF18428.1 AIM22470.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.5 1 1 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain CheB_methylest PF01339.17 AIM22471.1 - 2.5e-63 212.9 0.1 4.2e-63 212.1 0.1 1.4 1 0 0 1 1 1 1 CheB methylesterase Response_reg PF00072.24 AIM22471.1 - 4.1e-24 84.9 0.1 1.2e-23 83.4 0.1 1.8 1 0 0 1 1 1 1 Response regulator receiver domain CheR PF01739.18 AIM22472.1 - 1.3e-56 191.1 0.0 2.3e-56 190.4 0.0 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain CheR_N PF03705.15 AIM22472.1 - 4.2e-19 68.0 1.3 8.6e-19 67.0 1.3 1.5 1 0 0 1 1 1 1 CheR methyltransferase, all-alpha domain Methyltransf_25 PF13649.6 AIM22472.1 - 6.6e-07 30.0 0.0 0.00031 21.4 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIM22472.1 - 2.7e-06 28.1 0.0 4.1e-05 24.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AIM22472.1 - 0.00017 22.1 0.0 0.0028 18.3 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 AIM22472.1 - 0.058 13.2 0.0 0.095 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 AIM22472.1 - 0.19 11.5 0.0 0.52 10.1 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain MCPsignal PF00015.21 AIM22473.1 - 1.4e-56 191.0 26.2 5.7e-55 185.8 18.6 2.6 2 0 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain TarH PF02203.15 AIM22473.1 - 8.3e-53 178.9 7.7 8.3e-53 178.9 7.7 4.1 5 0 0 5 5 5 1 Tar ligand binding domain homologue HAMP PF00672.25 AIM22473.1 - 7.1e-13 48.7 3.9 8.4e-12 45.3 0.1 3.9 3 2 0 3 3 3 1 HAMP domain YibE_F PF07907.11 AIM22473.1 - 0.02 14.4 0.7 0.069 12.6 0.6 1.9 1 1 0 1 1 1 0 YibE/F-like protein Rotamase PF00639.21 AIM22473.1 - 0.025 15.5 1.0 0.025 15.5 1.0 3.2 3 0 0 3 3 3 0 PPIC-type PPIASE domain DUF948 PF06103.11 AIM22473.1 - 0.55 10.5 26.0 2.6 8.4 0.4 6.2 4 2 1 5 5 5 0 Bacterial protein of unknown function (DUF948) AIP3 PF03915.13 AIM22473.1 - 1.4 8.0 8.9 3 6.8 0.9 2.8 3 0 0 3 3 3 0 Actin interacting protein 3 Fib_alpha PF08702.10 AIM22473.1 - 1.6 8.9 9.6 20 5.4 0.6 3.5 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Jnk-SapK_ap_N PF09744.9 AIM22473.1 - 2.7 8.2 11.0 8.1 6.6 0.6 3.3 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 Vps53_N PF04100.12 AIM22473.1 - 5.3 5.9 8.8 1.7 7.6 2.7 2.4 2 0 0 2 2 2 0 Vps53-like, N-terminal MCPsignal PF00015.21 AIM22474.1 - 6e-60 202.0 28.9 8.6e-59 198.2 17.3 2.4 2 0 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain TarH PF02203.15 AIM22474.1 - 1.2e-55 188.2 1.3 1.2e-55 188.2 1.3 4.1 4 1 1 5 5 5 1 Tar ligand binding domain homologue HAMP PF00672.25 AIM22474.1 - 4.2e-12 46.3 4.8 7.2e-12 45.5 0.1 3.4 4 0 0 4 4 4 1 HAMP domain COG6 PF06419.11 AIM22474.1 - 0.019 13.2 0.3 0.019 13.2 0.3 2.2 2 0 0 2 2 2 0 Conserved oligomeric complex COG6 CheW PF01584.19 AIM22475.1 - 1.5e-37 128.3 1.3 1.7e-37 128.1 1.3 1.1 1 0 0 1 1 1 1 CheW-like domain CheW PF01584.19 AIM22476.1 - 1.3e-26 92.9 1.0 2.4e-26 92.0 1.0 1.4 1 0 0 1 1 1 1 CheW-like domain CheY-binding PF09078.11 AIM22476.1 - 6.2e-24 83.9 0.1 1.5e-23 82.7 0.1 1.7 1 0 0 1 1 1 1 CheY binding Hpt PF01627.23 AIM22476.1 - 1.6e-18 66.7 4.4 2.5e-18 66.1 0.4 2.8 2 0 0 2 2 2 1 Hpt domain HATPase_c PF02518.26 AIM22476.1 - 2.8e-18 66.4 0.3 7.2e-18 65.1 0.1 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase H-kinase_dim PF02895.14 AIM22476.1 - 4e-17 62.4 1.8 4e-17 62.4 1.8 2.2 2 0 0 2 2 2 1 Signal transducing histidine kinase, homodimeric domain HATPase_c_3 PF13589.6 AIM22476.1 - 0.16 11.8 0.1 0.36 10.6 0.1 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SAP130_C PF16014.5 AIM22476.1 - 5.7 5.9 14.7 0.12 11.5 6.4 2.0 2 0 0 2 2 2 0 Histone deacetylase complex subunit SAP130 C-terminus MotB_plug PF13677.6 AIM22477.1 - 4.4e-20 71.0 0.4 8e-20 70.2 0.4 1.4 1 0 0 1 1 1 1 Membrane MotB of proton-channel complex MotA/MotB OmpA PF00691.20 AIM22477.1 - 1.9e-13 50.6 0.0 3.6e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 OmpA family MotA_ExbB PF01618.16 AIM22478.1 - 1.4e-12 47.4 1.1 2.3e-12 46.7 1.1 1.3 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family SpoVAB PF13782.6 AIM22478.1 - 0.041 14.2 7.0 0.4 11.0 2.4 2.3 2 0 0 2 2 2 0 Stage V sporulation protein AB DUF1129 PF06570.11 AIM22478.1 - 0.1 12.1 0.1 0.18 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) ECF_trnsprt PF12822.7 AIM22478.1 - 0.17 11.9 6.1 0.075 13.1 0.6 2.4 2 1 0 2 2 2 0 ECF transporter, substrate-specific component FlhC PF05280.11 AIM22479.1 - 8.6e-84 279.5 0.1 9.8e-84 279.3 0.1 1.0 1 0 0 1 1 1 1 Flagellar transcriptional activator (FlhC) FlhD PF05247.13 AIM22480.1 - 5.9e-41 138.9 3.3 7e-41 138.6 3.3 1.1 1 0 0 1 1 1 1 Flagellar transcriptional activator (FlhD) DUF2857 PF11198.8 AIM22480.1 - 0.0012 18.7 1.4 0.0014 18.5 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2857) HHA PF05321.11 AIM22481.1 - 1.4e-29 102.1 0.1 2e-29 101.6 0.1 1.2 1 0 0 1 1 1 1 Haemolysin expression modulating protein Usp PF00582.26 AIM22482.1 - 4.4e-11 43.5 0.0 5e-11 43.3 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family ADH_N_2 PF16884.5 AIM22483.1 - 3.3e-42 142.8 0.0 6.3e-42 141.9 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 AIM22483.1 - 2e-18 66.6 0.1 4.2e-18 65.6 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AIM22483.1 - 4.5e-15 56.9 0.0 8.2e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase HupF_HypC PF01455.18 AIM22483.1 - 0.11 12.6 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 HupF/HypC family Peptidase_C15 PF01470.17 AIM22484.1 - 1.2e-70 237.8 0.1 1.5e-70 237.5 0.1 1.0 1 0 0 1 1 1 1 Pyroglutamyl peptidase LysR_substrate PF03466.20 AIM22485.1 - 1.8e-27 96.1 9.0 1.8e-27 96.1 9.0 1.5 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AIM22485.1 - 1.2e-17 63.6 0.1 2.6e-17 62.5 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family Phage_GPD PF05954.11 AIM22486.1 - 2.9e-90 302.6 0.4 6.4e-90 301.5 0.4 1.6 1 0 0 1 1 1 1 Phage late control gene D protein (GPD) FlgT_C PF16538.5 AIM22486.1 - 0.017 15.6 1.6 3.1 8.4 0.3 3.5 3 0 0 3 3 3 0 Flagellar assembly protein T, C-terminal domain Phage_base_V PF04717.12 AIM22486.1 - 0.11 12.5 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 Type VI secretion system, phage-baseplate injector Gp5_C PF06715.12 AIM22486.1 - 0.76 10.0 18.9 0.29 11.4 0.4 5.3 4 1 2 6 6 6 0 Gp5 C-terminal repeat (3 copies) Chlorovi_GP_rpt PF06598.11 AIM22486.1 - 4.1 7.6 7.0 5.1 7.2 0.1 3.2 3 0 0 3 3 3 0 Chlorovirus glycoprotein repeat MTABC_N PF16185.5 AIM22487.1 - 0.49 9.8 4.0 0.11 12.0 0.6 1.5 2 0 0 2 2 2 0 Mitochondrial ABC-transporter N-terminal five TM region Pentapeptide PF00805.22 AIM22489.1 - 8.8e-47 156.3 52.7 3e-11 42.7 5.4 9.1 3 3 3 9 9 9 8 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 AIM22489.1 - 3.7e-38 129.5 27.9 3.5e-10 39.9 0.2 5.6 1 1 5 6 6 6 6 Pentapeptide repeats (9 copies) DUF2169 PF09937.9 AIM22489.1 - 4e-30 105.3 2.0 4e-30 105.3 2.0 1.5 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2169) Pentapeptide_3 PF13576.6 AIM22489.1 - 1e-27 96.0 29.3 2.8e-07 30.6 1.4 7.4 3 2 5 8 8 8 8 Pentapeptide repeats (9 copies) CBM_5_12_2 PF14600.6 AIM22489.1 - 0.1 12.5 0.1 1 9.3 0.0 2.7 2 1 0 2 2 2 0 Cellulose-binding domain Pentapeptide PF00805.22 AIM22490.1 - 5e-41 137.9 39.6 5.4e-08 32.3 0.9 8.2 4 2 4 8 8 8 8 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 AIM22490.1 - 1.7e-39 133.8 33.2 6.6e-12 45.4 2.0 5.8 1 1 4 5 5 5 5 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 AIM22490.1 - 1.1e-23 83.1 38.2 1.9e-05 24.7 2.9 7.6 3 2 1 5 5 5 5 Pentapeptide repeats (9 copies) NOD2_WH PF17779.1 AIM22490.1 - 0.0043 17.4 1.8 8.1 6.9 0.0 4.6 3 2 2 5 5 5 2 NOD2 winged helix domain TPR_7 PF13176.6 AIM22490.1 - 0.23 11.6 1.4 3.2 8.0 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3540 PF12059.8 AIM22491.1 - 1.2e-62 211.3 0.6 1.4e-62 211.1 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3540) DUF4150 PF13665.6 AIM22492.1 - 6.6e-40 135.6 1.0 7.6e-40 135.4 1.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4150) LPAM_1 PF08139.12 AIM22493.1 - 0.051 14.1 2.3 0.095 13.2 1.4 1.9 2 0 0 2 2 2 0 Prokaryotic membrane lipoprotein lipid attachment site T6SS-SciN PF12790.7 AIM22494.1 - 6.1e-29 100.2 0.0 7.6e-29 99.9 0.0 1.1 1 0 0 1 1 1 1 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 T6SS_VasE PF05936.12 AIM22495.1 - 4.4e-154 513.3 1.0 5e-154 513.1 1.0 1.0 1 0 0 1 1 1 1 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE DotU PF09850.9 AIM22496.1 - 4.3e-70 235.6 0.4 4.3e-70 235.6 0.4 1.5 2 0 0 2 2 2 1 Type VI secretion system protein DotU OmpA PF00691.20 AIM22496.1 - 2.5e-16 59.8 0.1 4.6e-16 59.0 0.1 1.4 1 0 0 1 1 1 1 OmpA family ImcF-related_N PF14331.6 AIM22497.1 - 6.1e-98 327.3 2.5 6.1e-98 327.3 2.5 1.8 2 0 0 2 2 2 1 ImcF-related N-terminal domain IcmF-related PF06761.12 AIM22497.1 - 1.1e-85 287.8 4.9 2.4e-85 286.7 4.9 1.6 1 0 0 1 1 1 1 Intracellular multiplication and human macrophage-killing IcmF_C PF06744.12 AIM22497.1 - 6.7e-56 189.1 0.4 4.4e-55 186.5 0.1 2.5 2 0 0 2 2 2 1 Type VI secretion protein IcmF C-terminal AAA_28 PF13521.6 AIM22497.1 - 0.026 14.8 0.1 1 9.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain Wzy_C PF04932.15 AIM22497.1 - 0.13 11.9 0.3 18 5.0 0.1 2.3 2 0 0 2 2 2 0 O-Antigen ligase ABC_trans_CmpB PF06541.11 AIM22497.1 - 0.35 11.1 1.8 0.31 11.3 0.1 1.7 2 0 0 2 2 2 0 Putative ABC-transporter type IV TagF_N PF09867.9 AIM22498.1 - 1.1e-44 151.7 0.1 1.7e-44 151.1 0.1 1.3 1 0 0 1 1 1 1 TagF N-terminal domain, Type VI secretion system-associated ImpA_N PF06812.12 AIM22499.1 - 8.9e-38 129.1 0.1 1.7e-37 128.1 0.1 1.5 1 0 0 1 1 1 1 ImpA, N-terminal, type VI secretion system DUF4197 PF13852.6 AIM22499.1 - 0.044 13.5 0.1 0.08 12.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4197) Nitr_red_assoc PF09655.10 AIM22499.1 - 0.15 12.7 0.1 0.43 11.2 0.0 1.7 2 0 0 2 2 2 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) T6SS_VipA PF05591.12 AIM22500.1 - 2.4e-58 196.3 0.5 2.8e-58 196.1 0.5 1.0 1 0 0 1 1 1 1 Type VI secretion system, VipA, VC_A0107 or Hcp2 Tricho_coat PF05892.11 AIM22500.1 - 0.14 11.9 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Trichovirus coat protein VipB PF05943.12 AIM22501.1 - 1.2e-193 643.7 0.0 1.4e-193 643.5 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion protein, EvpB/VC_A0108, tail sheath DUF1877 PF08974.10 AIM22501.1 - 0.0049 17.0 0.1 0.011 15.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1877) SH2_2 PF14633.6 AIM22501.1 - 0.074 12.4 0.2 0.14 11.5 0.2 1.4 1 0 0 1 1 1 0 SH2 domain T6SS_HCP PF05638.12 AIM22502.1 - 9.2e-38 129.6 0.0 1.1e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 Type VI secretion system effector, Hcp Rota_VP4_MID PF17477.2 AIM22502.1 - 0.1 12.0 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 Rotavirus VP4 membrane interaction domain PG_binding_1 PF01471.18 AIM22503.1 - 5.5e-12 45.7 0.0 1.1e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Phage_lysozyme PF00959.19 AIM22503.1 - 1.1e-07 32.2 0.0 2e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Phage lysozyme Pesticin PF16754.5 AIM22503.1 - 1.7e-06 28.1 0.0 2.6e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial toxin homologue of phage lysozyme, C-term PG_binding_3 PF09374.10 AIM22503.1 - 1.9e-05 24.8 0.1 0.012 15.9 0.1 2.4 1 1 0 1 1 1 1 Predicted Peptidoglycan domain Tai4 PF16695.5 AIM22504.1 - 2.6e-20 72.7 0.3 3.6e-20 72.3 0.3 1.2 1 0 0 1 1 1 1 Type VI secretion system (T6SS), amidase immunity protein Tai4 PF16695.5 AIM22505.1 - 3.1e-13 50.1 0.2 3.8e-13 49.8 0.2 1.1 1 0 0 1 1 1 1 Type VI secretion system (T6SS), amidase immunity protein DUF4064 PF13273.6 AIM22506.1 - 0.00036 20.8 0.3 0.00087 19.5 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4064) DUF996 PF06195.13 AIM22506.1 - 0.00076 19.8 0.4 0.00095 19.5 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF996) Yip1 PF04893.17 AIM22506.1 - 0.0018 18.0 2.6 0.0022 17.7 2.6 1.3 1 1 0 1 1 1 1 Yip1 domain O-ag_pol_Wzy PF14296.6 AIM22506.1 - 0.0071 15.1 10.1 0.008 14.9 10.1 1.0 1 0 0 1 1 1 1 O-antigen polysaccharide polymerase Wzy GPR_Gpa2_C PF11970.8 AIM22506.1 - 0.024 14.7 0.9 0.047 13.8 0.9 1.4 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 C-term DUF1761 PF08570.10 AIM22506.1 - 0.047 13.9 2.4 0.048 13.9 0.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1761) DUF5360 PF17314.2 AIM22506.1 - 0.062 13.4 3.5 0.28 11.2 3.5 1.9 1 1 0 1 1 1 0 Family of unknown function (DUF5360) Phage_holin_2_1 PF04971.12 AIM22506.1 - 0.25 11.4 0.3 0.25 11.4 0.3 2.2 3 0 0 3 3 3 0 Bacteriophage P21 holin S FixP_N PF14715.6 AIM22506.1 - 9.8 6.0 7.4 2.5 7.9 0.5 2.3 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP FHA PF00498.26 AIM22507.1 - 4.1e-08 33.5 0.3 8.8e-08 32.4 0.3 1.5 1 0 0 1 1 1 1 FHA domain UreE_N PF02814.15 AIM22507.1 - 0.011 15.3 0.4 0.27 10.9 0.3 2.4 2 0 0 2 2 2 0 UreE urease accessory protein, N-terminal domain Yop-YscD_cpl PF16697.5 AIM22507.1 - 0.11 12.8 0.1 0.25 11.7 0.1 1.5 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain PP2C_2 PF13672.6 AIM22508.1 - 1.5e-14 54.1 0.7 1.9e-14 53.8 0.7 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 AIM22508.1 - 2.4e-09 37.2 1.1 1.1e-08 35.1 0.2 1.9 2 0 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.12 AIM22508.1 - 1e-07 32.1 0.0 7.5e-07 29.2 0.0 2.1 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) ImpE PF07024.13 AIM22510.1 - 7e-42 142.4 0.2 1.5e-41 141.3 0.0 1.6 2 1 0 2 2 2 1 ImpE protein TPR_19 PF14559.6 AIM22510.1 - 0.002 18.6 0.8 0.002 18.6 0.8 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat GPW_gp25 PF04965.14 AIM22511.1 - 1.4e-20 72.9 0.0 1.9e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 Gene 25-like lysozyme DUF5600 PF18150.1 AIM22511.1 - 0.012 16.2 0.0 0.016 15.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5600) T6SS_TssF PF05947.12 AIM22512.1 - 1.7e-233 776.6 0.1 1.9e-233 776.4 0.1 1.0 1 0 0 1 1 1 1 Type VI secretion system, TssF T6SS_TssG PF06996.11 AIM22513.1 - 1.4e-101 339.7 3.2 1.6e-101 339.5 3.2 1.0 1 0 0 1 1 1 1 Type VI secretion, TssG AAA_2 PF07724.14 AIM22514.1 - 4.3e-39 134.4 0.0 6e-38 130.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 AIM22514.1 - 1.1e-26 92.8 0.6 1.1e-26 92.8 0.6 2.4 1 1 1 2 2 2 1 AAA lid domain AAA PF00004.29 AIM22514.1 - 4.6e-21 75.6 0.0 7.1e-10 39.4 0.0 3.5 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 AIM22514.1 - 8e-14 51.5 0.0 8e-14 51.5 0.0 3.6 4 1 1 5 5 3 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 AIM22514.1 - 1.7e-12 47.6 0.3 6.2e-09 36.0 0.0 3.5 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AIM22514.1 - 1.2e-07 32.3 24.2 1.7e-06 28.5 0.5 6.7 4 2 0 5 5 3 2 AAA ATPase domain Sigma54_activat PF00158.26 AIM22514.1 - 3.1e-07 30.3 0.0 0.00018 21.2 0.0 2.8 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_22 PF13401.6 AIM22514.1 - 1.6e-06 28.4 4.8 0.22 11.8 0.0 5.4 5 1 0 5 5 3 2 AAA domain AAA_7 PF12775.7 AIM22514.1 - 1.2e-05 25.0 0.0 0.11 12.1 0.1 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_25 PF13481.6 AIM22514.1 - 4.7e-05 23.0 0.6 0.4 10.2 0.0 3.3 3 1 0 3 3 2 2 AAA domain AAA_14 PF13173.6 AIM22514.1 - 7.4e-05 22.8 0.0 0.16 12.0 0.0 4.4 3 1 1 4 4 4 1 AAA domain ATPase_2 PF01637.18 AIM22514.1 - 8.7e-05 22.5 0.0 0.19 11.6 0.0 3.4 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea TniB PF05621.11 AIM22514.1 - 0.00011 21.7 0.0 0.064 12.7 0.0 3.3 2 1 0 2 2 2 1 Bacterial TniB protein NACHT PF05729.12 AIM22514.1 - 0.00022 21.2 0.4 0.19 11.7 0.1 3.6 2 1 0 2 2 2 1 NACHT domain Zeta_toxin PF06414.12 AIM22514.1 - 0.00049 19.4 0.1 0.0075 15.6 0.0 2.7 3 0 0 3 3 3 1 Zeta toxin IstB_IS21 PF01695.17 AIM22514.1 - 0.00058 19.6 0.0 0.47 10.2 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_18 PF13238.6 AIM22514.1 - 0.00069 20.2 1.6 0.26 11.8 0.1 3.4 4 0 0 4 4 3 1 AAA domain Clp_N PF02861.20 AIM22514.1 - 0.00073 19.6 0.0 0.00073 19.6 0.0 3.6 4 0 0 4 4 3 1 Clp amino terminal domain, pathogenicity island component AAA_29 PF13555.6 AIM22514.1 - 0.001 18.8 0.0 1.6 8.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain TSKS PF15358.6 AIM22514.1 - 0.0024 16.3 2.4 0.0024 16.3 2.4 2.0 2 0 0 2 2 2 1 Testis-specific serine kinase substrate RuvB_N PF05496.12 AIM22514.1 - 0.0028 17.4 1.9 1.5 8.6 0.0 3.9 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 AIM22514.1 - 0.0099 15.1 0.0 0.78 8.9 0.0 2.9 3 0 0 3 3 3 1 TIP49 P-loop domain Rad17 PF03215.15 AIM22514.1 - 0.014 15.3 0.0 1.5 8.7 0.0 2.7 3 0 0 3 3 3 0 Rad17 P-loop domain Hpr_kinase_C PF07475.12 AIM22514.1 - 0.014 14.9 0.2 0.27 10.7 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain RNA_helicase PF00910.22 AIM22514.1 - 0.014 15.8 0.0 8.5 6.8 0.0 3.3 4 0 0 4 4 3 0 RNA helicase TsaE PF02367.17 AIM22514.1 - 0.016 15.2 0.0 2.1 8.3 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 AIM22514.1 - 0.016 14.9 0.0 1.2 8.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 AIM22514.1 - 0.017 14.2 0.0 0.44 9.6 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein ResIII PF04851.15 AIM22514.1 - 0.019 15.0 0.0 2.6 8.0 0.0 3.1 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 AIM22514.1 - 0.019 15.3 1.3 4.8 7.5 0.2 3.5 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 AIM22514.1 - 0.021 14.7 0.0 8.9 6.2 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase DUF815 PF05673.13 AIM22514.1 - 0.024 13.8 0.0 0.44 9.7 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF815) CbiA PF01656.23 AIM22514.1 - 0.033 14.2 0.4 0.47 10.5 0.0 2.8 3 1 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.15 AIM22514.1 - 0.034 14.0 1.0 9.5 6.1 0.0 2.9 3 0 0 3 3 2 0 NTPase SRP54 PF00448.22 AIM22514.1 - 0.035 13.7 0.1 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_23 PF13476.6 AIM22514.1 - 0.057 13.9 5.4 25 5.3 0.0 3.6 3 1 0 3 3 3 0 AAA domain AAA_6 PF12774.7 AIM22514.1 - 0.17 10.8 0.3 0.54 9.2 0.1 1.9 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region Microcephalin PF12258.8 AIM22514.1 - 0.2 10.9 0.0 0.42 9.8 0.0 1.4 1 0 0 1 1 1 0 Microcephalin protein Baculo_PEP_C PF04513.12 AIM22514.1 - 0.36 10.9 3.0 2 8.5 2.4 2.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-H PF05837.12 AIM22514.1 - 0.59 10.6 4.4 0.7 10.3 2.7 2.0 2 0 0 2 2 1 0 Centromere protein H (CENP-H) ABC_tran_CTD PF16326.5 AIM22514.1 - 0.66 10.3 16.4 0.079 13.2 3.9 2.9 1 1 1 2 2 2 0 ABC transporter C-terminal domain OmpH PF03938.14 AIM22514.1 - 2 8.8 7.5 5.5 7.3 7.5 1.7 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2968 PF11180.8 AIM22514.1 - 6.8 6.3 17.2 0.95 9.1 12.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Pkinase PF00069.25 AIM22515.1 - 3.3e-26 92.2 0.0 5.8e-26 91.4 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AIM22515.1 - 1.7e-15 57.1 0.0 1.6e-14 53.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 AIM22515.1 - 0.0017 18.3 0.2 0.0051 16.8 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 AIM22515.1 - 0.02 13.7 0.0 0.031 13.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase CarboxypepD_reg PF13620.6 AIM22515.1 - 0.024 14.9 0.0 0.064 13.5 0.0 1.7 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain Phage_GPD PF05954.11 AIM22516.1 - 1.5e-90 303.5 0.1 2.1e-90 303.1 0.1 1.2 1 0 0 1 1 1 1 Phage late control gene D protein (GPD) Gp5_C PF06715.12 AIM22516.1 - 0.0076 16.3 1.7 0.021 14.9 1.7 1.8 1 0 0 1 1 1 1 Gp5 C-terminal repeat (3 copies) GyrI-like PF06445.15 AIM22517.1 - 1.5e-27 96.8 0.0 1.6e-27 96.7 0.0 1.0 1 0 0 1 1 1 1 GyrI-like small molecule binding domain Cass2 PF14526.6 AIM22517.1 - 6e-17 62.2 0.0 6.6e-17 62.1 0.0 1.0 1 0 0 1 1 1 1 Integron-associated effector binding protein Trp_dioxygenase PF03301.13 AIM22518.1 - 9.8e-67 225.7 0.1 1.8e-41 142.7 0.0 3.0 1 1 1 2 2 2 2 Tryptophan 2,3-dioxygenase Peripla_BP_3 PF13377.6 AIM22519.1 - 1.8e-30 106.5 2.7 1.8e-29 103.2 0.0 2.4 1 1 2 3 3 3 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 AIM22519.1 - 1.3e-18 67.5 0.0 1.9e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 AIM22519.1 - 8.8e-17 60.6 0.4 1.9e-16 59.6 0.1 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 AIM22519.1 - 9.6e-17 61.4 0.0 1.8e-16 60.5 0.0 1.5 2 0 0 2 2 2 1 Periplasmic binding protein domain HTH_31 PF13560.6 AIM22519.1 - 0.0041 17.4 0.1 0.013 15.8 0.1 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 AIM22519.1 - 0.067 13.6 0.0 0.17 12.4 0.0 1.7 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_19 PF12844.7 AIM22519.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain adh_short_C2 PF13561.6 AIM22520.1 - 2.9e-54 184.1 1.0 3.6e-54 183.8 1.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AIM22520.1 - 7e-45 152.9 0.1 8.3e-45 152.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AIM22520.1 - 0.0051 16.7 0.2 0.0086 16.0 0.2 1.4 1 1 0 1 1 1 1 KR domain NanE PF04131.14 AIM22520.1 - 0.15 11.3 0.0 0.38 9.9 0.0 1.8 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase RbsD_FucU PF05025.13 AIM22521.1 - 1.4e-23 83.8 0.0 1.5e-23 83.7 0.0 1.0 1 0 0 1 1 1 1 RbsD / FucU transport protein family Colicin PF01024.19 AIM22522.1 - 1.9e-33 115.9 3.3 2.8e-33 115.4 3.3 1.2 1 0 0 1 1 1 1 Colicin pore forming domain PhoU_div PF01865.16 AIM22522.1 - 0.029 13.7 0.3 0.044 13.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF47 Transketolase_C PF02780.20 AIM22523.1 - 0.039 13.8 0.0 0.084 12.8 0.0 1.5 1 0 0 1 1 1 0 Transketolase, C-terminal domain MarR PF01047.22 AIM22524.1 - 1.3e-08 34.7 0.1 2.4e-08 33.8 0.1 1.5 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 AIM22524.1 - 3.3e-08 33.3 0.1 5.5e-08 32.6 0.1 1.4 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 AIM22524.1 - 4.1e-06 27.2 0.3 7.2e-06 26.4 0.3 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain HxlR PF01638.17 AIM22524.1 - 0.0042 16.9 0.1 0.0069 16.2 0.1 1.4 1 0 0 1 1 1 1 HxlR-like helix-turn-helix HTH_Crp_2 PF13545.6 AIM22524.1 - 0.035 14.1 0.2 0.14 12.2 0.1 2.0 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain Sigma70_r4_2 PF08281.12 AIM22524.1 - 0.049 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 TIR_2 PF13676.6 AIM22524.1 - 0.061 13.9 0.1 0.16 12.6 0.0 1.6 1 1 0 2 2 2 0 TIR domain PDH_E1_M PF17831.1 AIM22525.1 - 1.3e-101 339.0 0.0 2.2e-101 338.2 0.0 1.4 1 0 0 1 1 1 1 Pyruvate dehydrogenase E1 component middle domain Transketolase_N PF00456.21 AIM22525.1 - 3.9e-13 49.1 0.0 4.3e-07 29.2 0.0 2.2 2 0 0 2 2 2 2 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.20 AIM22525.1 - 0.0041 17.0 0.0 0.0092 15.9 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain IMS PF00817.20 AIM22526.1 - 2.4e-35 121.8 0.1 8.1e-35 120.0 0.0 1.9 2 0 0 2 2 2 1 impB/mucB/samB family DUF4113 PF13438.6 AIM22526.1 - 2.7e-21 75.4 0.1 6.2e-21 74.2 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4113) IMS_C PF11799.8 AIM22526.1 - 4.3e-14 53.2 0.0 1e-13 52.0 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 AIM22526.1 - 7.6e-06 26.0 0.0 2e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif Transposase_24 PF03004.14 AIM22526.1 - 0.089 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Plant transposase (Ptta/En/Spm family) DNA_pol_lambd_f PF10391.9 AIM22526.1 - 0.14 12.0 0.1 0.57 10.1 0.0 2.0 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda Peptidase_S24 PF00717.23 AIM22527.1 - 3e-13 49.5 0.0 4.2e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like FdhD-NarQ PF02634.15 AIM22528.1 - 4.2e-72 242.7 0.0 5e-72 242.4 0.0 1.1 1 0 0 1 1 1 1 FdhD/NarQ family Bestrophin PF01062.21 AIM22529.1 - 3.4e-58 197.4 0.7 3.8e-58 197.2 0.7 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DUF4321 PF14209.6 AIM22529.1 - 0.43 10.5 5.3 0.32 10.9 1.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4321) Dyp_perox PF04261.12 AIM22530.1 - 2.5e-93 312.6 0.0 2.9e-93 312.4 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family FtsK_gamma PF09397.10 AIM22530.1 - 0.092 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Ftsk gamma domain DUF3107 PF11305.8 AIM22530.1 - 0.19 12.0 0.0 6.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3107) ArsC PF03960.15 AIM22531.1 - 1.6e-17 63.2 0.0 2.3e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 ArsC family PGM_PMM_IV PF00408.20 AIM22531.1 - 0.0013 18.9 0.3 0.0029 17.7 0.1 1.7 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Glutaredoxin PF00462.24 AIM22531.1 - 0.036 14.3 0.0 0.11 12.8 0.0 1.7 1 1 1 2 2 2 0 Glutaredoxin ArsB PF02040.15 AIM22532.1 - 2.7e-159 531.0 31.8 3.1e-159 530.8 31.8 1.0 1 0 0 1 1 1 1 Arsenical pump membrane protein CitMHS PF03600.16 AIM22532.1 - 1.7e-24 86.6 42.8 1.7e-24 86.6 42.8 1.9 1 1 1 2 2 2 1 Citrate transporter Na_sulph_symp PF00939.19 AIM22532.1 - 0.035 13.1 35.9 0.35 9.8 5.8 2.6 2 1 0 2 2 2 0 Sodium:sulfate symporter transmembrane region HTH_5 PF01022.20 AIM22533.1 - 1.1e-13 50.8 1.2 1.6e-13 50.3 1.2 1.2 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 AIM22533.1 - 5e-08 32.9 1.0 7.4e-08 32.3 1.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 AIM22533.1 - 0.0078 15.7 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 AIM22533.1 - 0.037 13.8 1.2 0.037 13.8 1.2 1.8 2 0 0 2 2 2 0 IclR helix-turn-helix domain DUF4423 PF14394.6 AIM22533.1 - 0.07 12.8 0.0 0.08 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) TrmB PF01978.19 AIM22533.1 - 0.12 12.2 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_36 PF13730.6 AIM22533.1 - 0.12 12.3 0.0 0.83 9.7 0.0 2.1 1 1 0 1 1 1 0 Helix-turn-helix domain GCS2 PF04107.13 AIM22534.1 - 8.4e-52 176.3 0.0 1.1e-51 175.9 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase family 2(GCS2) GCS PF03074.16 AIM22534.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Glutamate-cysteine ligase YdiH PF15930.5 AIM22535.1 - 0.1 12.8 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF3570 PF12094.8 AIM22536.1 - 0.11 11.3 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3570) DUF3307 PF11750.8 AIM22537.1 - 7.2e-25 87.5 4.6 1.4e-24 86.6 4.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3307) E1-E2_ATPase PF00122.20 AIM22538.1 - 4.5e-39 133.8 1.9 4.5e-39 133.8 1.9 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 AIM22538.1 - 2.1e-19 70.7 0.8 5.9e-19 69.2 0.8 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 AIM22538.1 - 1.6e-17 63.8 7.6 1.6e-17 63.8 7.6 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 AIM22538.1 - 3.3e-16 58.7 0.0 6.8e-16 57.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 AIM22538.1 - 1.2e-06 28.5 0.0 6.1e-06 26.2 0.0 2.3 1 1 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 AIM22538.1 - 2.3e-06 27.5 0.1 0.0013 18.6 0.1 2.4 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 AIM22538.1 - 0.00075 20.0 0.1 0.0034 17.8 0.0 2.1 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Neurochondrin PF05536.11 AIM22538.1 - 0.075 11.4 0.0 0.21 9.9 0.0 1.6 2 0 0 2 2 2 0 Neurochondrin MgtC PF02308.16 AIM22539.1 - 3.9e-37 127.3 13.4 3.9e-37 127.3 11.7 1.7 2 0 0 2 2 2 1 MgtC family Glyco_hydro_129 PF11308.8 AIM22540.1 - 1.9e-138 461.1 0.1 2.6e-138 460.6 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases related to GH101 family, GH129 Plectin PF00681.20 AIM22540.1 - 0.13 12.1 0.0 1.2 9.1 0.0 2.5 2 0 0 2 2 2 0 Plectin repeat CoA_transf_3 PF02515.17 AIM22541.1 - 9.1e-47 159.9 2.3 9.3e-44 150.0 0.0 2.5 2 1 0 2 2 2 2 CoA-transferase family III zf-C2H2_jaz PF12171.8 AIM22541.1 - 0.27 11.6 0.0 0.42 11.0 0.0 1.3 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding LysR_substrate PF03466.20 AIM22542.1 - 4.1e-33 114.5 6.7 6.3e-33 113.9 6.7 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM22542.1 - 1.5e-13 50.5 0.8 1.5e-13 50.5 0.8 2.5 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family THDPS_N_2 PF14805.6 AIM22542.1 - 0.066 13.5 0.3 0.31 11.3 0.1 2.3 2 0 0 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Pyridoxal_deC PF00282.19 AIM22543.1 - 1.9e-41 142.0 0.0 2.5e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Acetyltransf_3 PF13302.7 AIM22544.1 - 4.1e-14 53.4 0.0 5.3e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AIM22544.1 - 2.7e-07 30.8 0.0 3.6e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 AIM22544.1 - 2.3e-05 24.6 0.0 2.8e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 AIM22544.1 - 0.0079 15.9 0.0 1 9.0 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain GerE PF00196.19 AIM22545.1 - 9.7e-18 63.5 1.6 1.8e-17 62.6 1.6 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family DSRB PF10781.9 AIM22546.1 - 1.6e-37 126.9 0.2 1.8e-37 126.8 0.2 1.0 1 0 0 1 1 1 1 Dextransucrase DSRB CSD PF00313.22 AIM22547.1 - 9.7e-33 111.8 1.0 1.1e-32 111.7 1.0 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 AIM22547.1 - 0.0011 18.6 0.2 0.0017 18.0 0.2 1.2 1 0 0 1 1 1 1 Ribonuclease B OB domain CusF_Ec PF11604.8 AIM22547.1 - 0.095 12.7 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Copper binding periplasmic protein CusF ADH_zinc_N_2 PF13602.6 AIM22550.1 - 3e-25 89.8 0.1 5.7e-25 88.9 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 AIM22550.1 - 1.1e-24 86.9 1.2 1.7e-24 86.3 1.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AIM22550.1 - 1.2e-11 44.5 0.1 6.4e-11 42.1 0.0 2.2 2 2 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain MccV PF17508.2 AIM22550.1 - 0.76 10.4 5.3 0.24 11.9 0.5 2.3 1 1 1 2 2 2 0 Microcin V bacteriocin Epimerase PF01370.21 AIM22551.1 - 1.6e-09 37.6 0.0 2.6e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 AIM22551.1 - 1.5e-06 28.2 0.0 2.2e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 AIM22551.1 - 0.00018 20.7 0.0 0.00031 20.0 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 AIM22551.1 - 0.013 14.9 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 AIM22551.1 - 0.068 12.6 0.0 0.092 12.1 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 AIM22551.1 - 0.18 10.8 0.0 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 AIM22551.1 - 0.19 11.6 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 KR domain DUF937 PF06078.11 AIM22552.1 - 1.1e-10 42.2 2.2 1.7e-10 41.6 2.2 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF937) Bac_DNA_binding PF00216.21 AIM22552.1 - 0.083 13.1 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial DNA-binding protein MarR_2 PF12802.7 AIM22552.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 MarR family Transgly_assoc PF04226.13 AIM22553.1 - 1.6e-15 57.0 11.2 1.6e-15 57.0 11.2 2.2 1 1 1 2 2 2 1 Transglycosylase associated protein DUF5518 PF17647.1 AIM22553.1 - 0.002 18.3 17.7 0.0022 18.1 17.7 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5518) Phage_holin_4_2 PF04020.13 AIM22553.1 - 0.26 12.0 7.9 1.1 10.0 1.8 2.0 1 1 1 2 2 2 0 Mycobacterial 4 TMS phage holin, superfamily IV DUF2632 PF10943.8 AIM22553.1 - 0.53 9.8 4.7 0.57 9.7 4.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2632) SLATT_fungal PF18142.1 AIM22553.1 - 1.1 9.2 3.3 1.5 8.9 2.3 1.9 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain NiFe_hyd_3_EhaA PF17367.2 AIM22553.1 - 7.8 6.7 12.9 4.3 7.5 1.2 2.8 1 1 2 3 3 3 0 NiFe-hydrogenase-type-3 Eha complex subunit A DUF883 PF05957.13 AIM22554.1 - 4.4e-10 40.0 0.0 5.1e-10 39.8 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) Lip_A_acyltrans PF03279.13 AIM22555.1 - 2.6e-75 253.3 0.0 3.1e-75 253.1 0.0 1.1 1 0 0 1 1 1 1 Bacterial lipid A biosynthesis acyltransferase 3-dmu-9_3-mt PF06983.13 AIM22556.1 - 9.2e-09 35.9 0.0 1.2e-08 35.4 0.0 1.2 1 0 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase DUF2569 PF10754.9 AIM22557.1 - 0.025 15.0 2.3 0.029 14.8 2.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) DUF4131 PF13567.6 AIM22557.1 - 0.044 13.4 6.8 0.047 13.3 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) MerT PF02411.15 AIM22557.1 - 0.071 13.1 0.8 0.071 13.1 0.8 1.4 1 1 0 1 1 1 0 MerT mercuric transport protein IPTL-CTERM PF18203.1 AIM22557.1 - 0.4 10.6 10.5 1.9 8.5 0.1 2.7 2 1 0 2 2 2 0 IPTL-CTERM motif GGDEF PF00990.21 AIM22558.1 - 3.4e-49 166.7 0.0 6.8e-49 165.7 0.0 1.5 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain dCache_1 PF02743.18 AIM22558.1 - 8e-20 71.7 0.4 8e-20 71.7 0.4 2.0 2 0 0 2 2 2 1 Cache domain PqiA PF04403.13 AIM22558.1 - 0.12 12.2 0.6 2.2 8.1 0.0 2.2 2 0 0 2 2 2 0 Paraquat-inducible protein A DUF4381 PF14316.6 AIM22558.1 - 0.55 10.5 3.1 2.2 8.5 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4381) Kdo_hydroxy PF11004.8 AIM22559.1 - 2.1e-112 374.9 0.1 2.3e-112 374.7 0.1 1.0 1 0 0 1 1 1 1 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase Aldedh PF00171.22 AIM22560.1 - 7.8e-61 206.0 0.0 9.4e-61 205.7 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MaoC_dehydratas PF01575.19 AIM22560.1 - 3.2e-29 101.0 0.0 8e-29 99.7 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain PaaA_PaaC PF05138.12 AIM22561.1 - 3.8e-98 327.8 4.6 4.2e-98 327.7 4.6 1.0 1 0 0 1 1 1 1 Phenylacetic acid catabolic protein PaaB PF06243.11 AIM22562.1 - 3.2e-39 133.0 0.0 3.5e-39 132.9 0.0 1.0 1 0 0 1 1 1 1 Phenylacetic acid degradation B PaaA_PaaC PF05138.12 AIM22563.1 - 7.5e-91 303.9 0.2 9e-91 303.7 0.2 1.0 1 0 0 1 1 1 1 Phenylacetic acid catabolic protein FeS_assembly_P PF01883.19 AIM22564.1 - 5.7e-12 45.6 0.0 4.5e-11 42.8 0.0 1.9 1 1 1 2 2 2 1 Iron-sulfur cluster assembly protein Zn_Tnp_IS1595 PF12760.7 AIM22564.1 - 0.037 14.0 9.5 0.089 12.8 9.5 1.8 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.10 AIM22564.1 - 7.3 6.8 13.1 0.96 9.6 0.9 2.8 2 0 0 2 2 2 0 Zinc ribbon domain NAD_binding_1 PF00175.21 AIM22565.1 - 1.1e-17 64.7 0.0 1.7e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Fer2 PF00111.27 AIM22565.1 - 1.2e-15 57.2 0.2 2.1e-15 56.4 0.2 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain FAD_binding_6 PF00970.24 AIM22565.1 - 1.7e-13 50.8 0.0 2.7e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 AIM22565.1 - 0.00011 22.3 0.0 0.0013 18.9 0.0 2.0 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Fer2_4 PF13510.6 AIM22565.1 - 0.0018 18.2 0.0 0.0036 17.3 0.0 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain ECH_1 PF00378.20 AIM22566.1 - 1.1e-69 234.6 0.1 1.2e-69 234.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AIM22566.1 - 4.6e-34 118.4 0.6 7.6e-28 98.0 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase ketoacyl-synt PF00109.26 AIM22566.1 - 0.0083 15.7 0.2 0.031 13.8 0.1 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain DUF4398 PF14346.6 AIM22566.1 - 0.023 15.3 2.5 0.023 15.3 2.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) ECH_1 PF00378.20 AIM22567.1 - 7.7e-67 225.2 0.0 8.7e-67 225.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AIM22567.1 - 1e-37 130.4 0.0 7.2e-36 124.3 0.0 1.9 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase KNTase_C PF07827.11 AIM22567.1 - 0.075 12.9 0.0 6.2 6.7 0.0 2.3 2 0 0 2 2 2 0 KNTase C-terminal domain 3HCDH_N PF02737.18 AIM22568.1 - 2.3e-62 210.1 0.1 6.7e-62 208.6 0.1 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 AIM22568.1 - 2.2e-35 121.1 0.2 9.9e-29 99.8 0.1 2.8 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 3HCDH_RFF PF18321.1 AIM22568.1 - 3.3e-24 85.1 0.1 3.3e-24 85.1 0.1 3.2 4 0 0 4 4 4 1 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain NAD_binding_2 PF03446.15 AIM22568.1 - 4.9e-06 26.8 0.2 5e-05 23.5 0.2 2.5 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 AIM22568.1 - 0.0011 18.9 0.0 0.0023 17.9 0.0 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.21 AIM22568.1 - 0.0014 17.9 1.5 0.0029 17.0 1.5 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 AIM22568.1 - 0.014 15.7 0.3 0.045 14.0 0.2 2.0 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox PF00070.27 AIM22568.1 - 0.016 15.7 0.1 0.038 14.5 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 AIM22568.1 - 0.018 15.6 0.4 0.059 14.0 0.4 2.0 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_2 PF07992.14 AIM22568.1 - 0.018 14.3 0.1 0.028 13.7 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CbiA PF01656.23 AIM22568.1 - 0.065 13.3 0.0 0.26 11.3 0.0 1.9 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short_C2 PF13561.6 AIM22568.1 - 0.065 12.8 0.8 0.17 11.4 0.8 1.7 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase 2-Hacid_dh_C PF02826.19 AIM22568.1 - 0.12 11.7 0.1 0.25 10.7 0.1 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 AIM22568.1 - 0.18 12.0 0.6 0.72 10.1 0.4 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain PALP PF00291.25 AIM22568.1 - 0.52 9.7 4.9 0.92 8.9 1.8 2.4 2 1 1 3 3 3 0 Pyridoxal-phosphate dependent enzyme HI0933_like PF03486.14 AIM22568.1 - 1.2 7.7 3.1 1.7 7.2 3.1 1.2 1 0 0 1 1 1 0 HI0933-like protein 4HBT PF03061.22 AIM22569.1 - 1.4e-18 67.0 0.1 2.1e-18 66.4 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 AIM22569.1 - 4.4e-06 26.9 0.1 6e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) 4HBT_3 PF13622.6 AIM22569.1 - 0.00028 21.2 0.8 0.00039 20.8 0.8 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily PS-DH PF14765.6 AIM22569.1 - 0.0018 17.6 0.0 0.0027 17.0 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.23 AIM22570.1 - 8.3e-74 248.2 0.1 1.1e-73 247.9 0.1 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 AIM22570.1 - 3.7e-44 149.3 0.4 3.7e-44 149.3 0.4 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 AIM22570.1 - 1.1e-05 25.2 0.5 2.9e-05 23.8 0.5 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 AIM22570.1 - 0.087 12.7 1.9 0.98 9.3 0.1 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III AMP-binding_C_2 PF14535.6 AIM22571.1 - 2.1e-27 95.2 0.0 4.3e-27 94.3 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 AIM22571.1 - 8.4e-16 57.6 0.4 2.2e-15 56.2 0.4 1.7 1 1 0 1 1 1 1 AMP-binding enzyme PaaX PF07848.12 AIM22572.1 - 2.1e-27 95.1 0.3 5.5e-27 93.8 0.3 1.7 1 0 0 1 1 1 1 PaaX-like protein PaaX_C PF08223.11 AIM22572.1 - 8.1e-27 93.4 0.0 1.3e-26 92.8 0.0 1.3 1 0 0 1 1 1 1 PaaX-like protein C-terminal domain Hexapep PF00132.24 AIM22573.1 - 1.5e-15 56.2 11.3 9.7e-08 31.5 0.4 4.3 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AIM22573.1 - 5.4e-05 22.8 10.7 0.24 11.2 1.2 4.0 2 2 0 3 3 3 3 Hexapeptide repeat of succinyl-transferase gpD PF02925.16 AIM22573.1 - 0.064 13.2 0.4 0.14 12.1 0.3 1.5 1 1 0 1 1 1 0 Bacteriophage scaffolding protein D Ral PF11058.8 AIM22573.1 - 0.18 11.4 0.1 0.84 9.2 0.0 2.0 1 1 1 2 2 2 0 Antirestriction protein Ral AA_permease PF00324.21 AIM22574.1 - 4.6e-86 289.3 53.9 5.6e-86 289.0 53.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 AIM22574.1 - 6.1e-38 130.8 57.0 7.4e-38 130.5 57.0 1.0 1 0 0 1 1 1 1 Amino acid permease TMEM192 PF14802.6 AIM22574.1 - 0.0031 16.7 0.6 0.011 14.8 0.6 1.9 1 0 0 1 1 1 1 TMEM192 family Aminotran_1_2 PF00155.21 AIM22575.1 - 1.7e-71 241.3 0.0 1.9e-71 241.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF463 PF04317.12 AIM22575.1 - 0.14 11.0 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 Ribonuc_L-PSP PF01042.21 AIM22576.1 - 4.4e-19 68.7 0.0 5.1e-19 68.5 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Abhydrolase_3 PF07859.13 AIM22577.1 - 4.7e-10 39.7 2.2 6.4e-08 32.7 0.8 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AIM22577.1 - 0.00025 21.7 10.2 0.0038 17.9 10.2 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AIM22577.1 - 0.00038 19.8 0.0 0.00081 18.7 0.0 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2974 PF11187.8 AIM22577.1 - 0.18 11.3 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) LysR_substrate PF03466.20 AIM22578.1 - 1.4e-40 138.9 7.9 2.5e-40 138.1 7.9 1.4 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM22578.1 - 7.5e-19 67.4 3.9 7.5e-19 67.4 3.9 2.2 3 0 0 3 3 3 1 Bacterial regulatory helix-turn-helix protein, lysR family DUF2249 PF10006.9 AIM22578.1 - 0.0096 15.8 1.3 0.038 13.9 0.1 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2249) GST_N_3 PF13417.6 AIM22579.1 - 4.5e-15 55.8 0.0 7.9e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 AIM22579.1 - 3.1e-12 46.6 0.0 5.6e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AIM22579.1 - 7.5e-09 35.8 0.0 1.4e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 AIM22579.1 - 2.3e-08 34.2 0.0 5.9e-08 32.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 AIM22579.1 - 0.00027 21.1 0.0 0.00057 20.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 AIM22579.1 - 0.00037 20.4 1.1 0.0028 17.6 0.2 2.6 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 AIM22579.1 - 0.00061 20.5 0.0 0.003 18.3 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase N-terminal domain Putative_PNPOx PF01243.20 AIM22580.1 - 1.8e-19 69.7 0.0 3.1e-11 43.3 0.0 3.1 2 2 1 3 3 3 2 Pyridoxamine 5'-phosphate oxidase GlgS PF08971.11 AIM22581.1 - 6e-13 48.6 0.4 7.1e-13 48.4 0.4 1.1 1 0 0 1 1 1 1 Glycogen synthesis protein Aldedh PF00171.22 AIM22582.1 - 8.5e-170 565.2 0.1 9.5e-170 565.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cass2 PF14526.6 AIM22583.1 - 2.9e-14 53.5 0.0 4.4e-14 52.9 0.0 1.3 1 1 0 1 1 1 1 Integron-associated effector binding protein GyrI-like PF06445.15 AIM22583.1 - 1.3e-08 35.3 0.4 1.1e-07 32.3 0.4 2.1 1 1 0 1 1 1 1 GyrI-like small molecule binding domain Glyoxalase PF00903.25 AIM22584.1 - 0.061 13.5 0.0 0.079 13.2 0.0 1.2 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Cupin_2 PF07883.11 AIM22585.1 - 3e-13 49.3 0.7 4.6e-13 48.7 0.7 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 AIM22585.1 - 5.5e-08 32.8 0.3 7.9e-08 32.3 0.3 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 AIM22585.1 - 7.1e-06 25.7 0.1 9.1e-06 25.4 0.1 1.1 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.7 AIM22585.1 - 0.0021 17.8 0.5 0.0025 17.6 0.5 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 AIM22585.1 - 0.034 13.8 0.1 0.68 9.7 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF861) Auxin_BP PF02041.16 AIM22585.1 - 0.068 12.8 0.0 0.087 12.5 0.0 1.2 1 0 0 1 1 1 0 Auxin binding protein Cupin_7 PF12973.7 AIM22585.1 - 0.085 12.8 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 ChrR Cupin-like domain ARD PF03079.14 AIM22585.1 - 0.1 12.8 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 ARD/ARD' family CHAP PF05257.16 AIM22585.1 - 0.27 11.8 4.0 0.46 11.1 3.9 1.5 1 1 0 1 1 1 0 CHAP domain LysR_substrate PF03466.20 AIM22586.1 - 4.2e-41 140.6 1.0 5.6e-41 140.2 1.0 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM22586.1 - 2e-20 72.5 2.8 3.3e-20 71.8 2.8 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_20 PF12840.7 AIM22586.1 - 0.0025 17.9 0.5 0.0065 16.5 0.5 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain Cro PF09048.10 AIM22586.1 - 0.016 15.2 0.0 0.06 13.4 0.1 1.9 2 0 0 2 2 2 0 Cro Mga PF05043.13 AIM22586.1 - 0.019 15.6 0.0 0.033 14.8 0.0 1.3 1 0 0 1 1 1 0 Mga helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 AIM22586.1 - 0.023 14.1 1.8 0.059 12.8 0.1 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.6 AIM22586.1 - 0.052 13.7 0.2 0.11 12.7 0.2 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_5 PF01022.20 AIM22586.1 - 0.081 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_34 PF13601.6 AIM22586.1 - 0.13 12.5 0.2 0.39 10.9 0.1 1.8 2 0 0 2 2 2 0 Winged helix DNA-binding domain HTH_50 PF18024.1 AIM22586.1 - 0.21 11.2 0.1 0.21 11.2 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain Aldo_ket_red PF00248.21 AIM22587.1 - 1.2e-74 251.2 0.0 1.3e-74 251.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AMP-binding PF00501.28 AIM22588.1 - 5.9e-249 825.7 0.0 3.6e-84 282.8 0.0 4.0 4 0 0 4 4 4 3 AMP-binding enzyme Condensation PF00668.20 AIM22588.1 - 3.1e-197 655.8 0.0 9.8e-88 294.8 0.0 3.2 3 0 0 3 3 3 3 Condensation domain PP-binding PF00550.25 AIM22588.1 - 1e-31 109.0 0.2 8e-10 38.9 0.0 4.1 4 0 0 4 4 4 3 Phosphopantetheine attachment site AMP-binding_C PF13193.6 AIM22588.1 - 1.7e-27 96.2 0.0 5.1e-10 40.2 0.0 4.0 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain Thioesterase PF00975.20 AIM22588.1 - 2.1e-17 64.1 0.1 6.9e-17 62.3 0.1 2.0 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 AIM22588.1 - 0.041 14.5 0.2 0.041 14.5 0.2 7.0 8 2 1 9 9 9 0 Alpha/beta hydrolase family WES_acyltransf PF03007.16 AIM22588.1 - 0.048 13.4 0.0 0.18 11.6 0.0 2.0 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain TonB_dep_Rec PF00593.24 AIM22589.1 - 3.7e-55 188.7 34.6 1.7e-54 186.4 33.9 1.9 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 AIM22589.1 - 2.6e-23 82.6 5.8 5.5e-23 81.6 3.2 2.5 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 AIM22589.1 - 1.6e-14 53.7 0.0 3.8e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 Outer membrane protein beta-barrel family Phenol_MetA_deg PF13557.6 AIM22589.1 - 7.9e-06 26.0 15.4 3.2e-05 24.0 0.9 3.9 4 0 0 4 4 4 2 Putative MetA-pathway of phenol degradation DUF2490 PF10677.9 AIM22589.1 - 0.065 13.2 0.7 14 5.5 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2490) DUF3575 PF12099.8 AIM22589.1 - 0.11 11.8 0.3 4.5 6.5 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3575) PQQ PF01011.21 AIM22590.1 - 1.1e-52 173.6 3.9 6e-08 32.3 0.0 8.4 8 0 0 8 8 8 7 PQQ enzyme repeat PQQ_2 PF13360.6 AIM22590.1 - 5e-19 68.8 0.0 2.4e-07 30.6 0.0 4.5 3 1 1 4 4 4 4 PQQ-like domain PQQ_3 PF13570.6 AIM22590.1 - 8.3e-11 42.0 10.4 0.18 12.3 0.1 8.3 7 2 0 7 7 7 4 PQQ-like domain SAYSvFN PF10260.9 AIM22590.1 - 0.1 12.5 4.4 0.2 11.6 0.0 2.8 2 2 1 3 3 3 0 Uncharacterized conserved domain (SAYSvFN) GerE PF00196.19 AIM22592.1 - 1.4e-13 50.1 0.0 2.2e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4 PF04545.16 AIM22592.1 - 0.00032 20.1 0.1 0.00068 19.1 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.6 AIM22592.1 - 0.00036 19.9 0.1 0.00071 18.9 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 Sigma70_r4_2 PF08281.12 AIM22592.1 - 0.00053 19.6 0.2 0.0013 18.3 0.2 1.7 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_28 PF13518.6 AIM22592.1 - 0.0039 17.3 0.1 0.035 14.2 0.0 2.3 1 1 1 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.7 AIM22592.1 - 0.052 13.4 0.7 0.16 11.8 0.1 2.1 2 0 0 2 2 2 0 MarR family HTH_23 PF13384.6 AIM22592.1 - 0.055 13.3 0.1 0.21 11.4 0.1 2.1 1 0 0 1 1 1 0 Homeodomain-like domain HTH_24 PF13412.6 AIM22592.1 - 0.15 11.6 0.0 0.37 10.4 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding PyrI_C PF02748.15 AIM22592.1 - 0.8 9.7 2.5 12 5.9 2.5 2.3 1 1 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Fimbrial PF00419.20 AIM22594.1 - 2.9e-12 47.1 0.0 3.6e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Fimbrial protein Fimbrial PF00419.20 AIM22595.1 - 1.5e-11 44.8 0.0 2.7e-11 44.0 0.0 1.4 1 1 0 1 1 1 1 Fimbrial protein Fimbrial PF00419.20 AIM22596.1 - 9.6e-14 51.9 0.0 1.3e-13 51.5 0.0 1.2 1 0 0 1 1 1 1 Fimbrial protein Fimbrial PF00419.20 AIM22597.1 - 5.3e-09 36.5 0.0 6.6e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Fimbrial protein PapD_N PF00345.20 AIM22598.1 - 1.2e-38 131.8 0.6 5.8e-38 129.6 0.6 1.8 2 0 0 2 2 2 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain PapD_C PF02753.17 AIM22598.1 - 4.8e-17 62.1 0.4 2e-16 60.1 0.1 2.2 2 0 0 2 2 2 1 Pili assembly chaperone PapD, C-terminal domain Usher PF00577.20 AIM22599.1 - 3.2e-192 640.2 18.3 3.9e-192 640.0 18.3 1.1 1 0 0 1 1 1 1 Outer membrane usher protein PapC_N PF13954.6 AIM22599.1 - 3.7e-24 85.4 0.0 1.2e-23 83.8 0.0 1.9 2 0 0 2 2 2 1 PapC N-terminal domain PapC_C PF13953.6 AIM22599.1 - 2.5e-13 49.6 0.1 1.1e-12 47.6 0.1 2.1 1 0 0 1 1 1 1 PapC C-terminal domain Big_6 PF17936.1 AIM22599.1 - 1.7 9.0 4.1 0.98 9.7 0.3 2.3 2 0 0 2 2 2 0 Bacterial Ig domain GFP PF01353.22 AIM22600.1 - 0.015 14.8 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 Green fluorescent protein Fimbrial PF00419.20 AIM22601.1 - 3.1e-17 63.3 5.7 3.7e-17 63.0 5.7 1.1 1 0 0 1 1 1 1 Fimbrial protein FaeA PF04703.12 AIM22602.1 - 0.00028 21.2 0.0 0.00035 20.9 0.0 1.3 1 0 0 1 1 1 1 FaeA-like protein DAZAP2 PF11029.8 AIM22602.1 - 0.079 13.9 0.1 0.1 13.6 0.1 1.2 1 0 0 1 1 1 0 DAZ associated protein 2 (DAZAP2) MatE PF01554.18 AIM22603.1 - 2.3e-53 180.1 29.5 8.6e-35 119.8 10.6 2.7 3 0 0 3 3 3 2 MatE Fumarate_red_C PF02300.17 AIM22603.1 - 0.01 15.9 1.8 0.032 14.3 0.6 2.4 1 1 1 2 2 2 0 Fumarate reductase subunit C T2SS_PulS_OutS PF09691.10 AIM22604.1 - 5.2e-18 65.2 0.0 6.4e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Type II secretion system pilotin lipoprotein (PulS_OutS) LPAM_1 PF08139.12 AIM22604.1 - 0.019 15.5 3.3 0.045 14.3 3.3 1.7 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site ABC_membrane PF00664.23 AIM22606.1 - 1e-44 153.2 22.5 2.2e-44 152.2 22.5 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region Peptidase_C39 PF03412.15 AIM22606.1 - 1.4e-36 125.2 0.0 2.4e-36 124.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase C39 family ABC_tran PF00005.27 AIM22606.1 - 8e-30 104.1 0.0 1.5e-29 103.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AIM22606.1 - 1.1e-05 25.0 0.4 0.00026 20.5 0.4 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Peptidase_C70 PF12385.8 AIM22606.1 - 0.00019 21.5 0.0 0.00061 19.8 0.0 1.9 1 1 0 1 1 1 1 Papain-like cysteine protease AvrRpt2 AAA_21 PF13304.6 AIM22606.1 - 0.0012 18.7 0.3 0.98 9.2 0.1 2.4 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AIM22606.1 - 0.0013 18.4 0.1 0.0053 16.5 0.1 2.0 1 0 0 1 1 1 1 P-loop containing region of AAA domain Mg_chelatase PF01078.21 AIM22606.1 - 0.0062 15.9 0.1 0.016 14.6 0.1 1.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Guanylate_cyc_2 PF09778.9 AIM22606.1 - 0.011 15.0 0.0 0.087 12.2 0.0 2.3 3 0 0 3 3 3 0 Guanylylate cyclase Peptidase_C39_2 PF13529.6 AIM22606.1 - 0.013 16.0 0.2 0.19 12.3 0.2 2.4 1 1 0 1 1 1 0 Peptidase_C39 like family RsgA_GTPase PF03193.16 AIM22606.1 - 0.015 15.2 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 AIM22606.1 - 0.015 15.7 0.0 0.03 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 AIM22606.1 - 0.067 13.3 0.1 0.15 12.1 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA PF00004.29 AIM22606.1 - 0.082 13.3 0.8 1.3 9.5 0.4 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 AIM22606.1 - 0.09 12.5 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AIM22606.1 - 0.095 12.3 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AIM22606.1 - 0.14 12.5 0.4 1 9.6 0.3 2.2 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 AIM22606.1 - 0.14 12.2 0.1 0.29 11.2 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain HlyD_3 PF13437.6 AIM22607.1 - 2e-13 51.0 0.0 3.5e-12 47.0 0.0 2.4 2 0 0 2 2 2 1 HlyD family secretion protein HlyD_D23 PF16576.5 AIM22607.1 - 5.5e-13 48.6 1.8 5.1e-10 38.9 0.1 2.2 2 0 0 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 AIM22607.1 - 8.9e-10 38.2 1.3 8e-05 22.4 0.2 3.4 2 1 1 3 3 3 2 Biotin-lipoyl like HlyD PF00529.20 AIM22607.1 - 5.9e-09 35.7 0.0 1.4e-08 34.5 0.0 1.9 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl PF00364.22 AIM22607.1 - 3.5e-06 26.7 0.7 0.02 14.7 0.3 2.5 2 0 0 2 2 2 2 Biotin-requiring enzyme Peptidase_M23 PF01551.22 AIM22607.1 - 0.011 15.9 0.1 1.2 9.3 0.0 2.7 2 0 0 2 2 2 0 Peptidase family M23 zf-C4H2 PF10146.9 AIM22607.1 - 0.014 15.7 5.1 0.021 15.1 5.1 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein TPR_MLP1_2 PF07926.12 AIM22607.1 - 0.096 12.8 15.3 0.86 9.7 0.7 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Exonuc_VII_L PF02601.15 AIM22607.1 - 0.1 12.1 7.4 0.17 11.4 7.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit PCRF PF03462.18 AIM22607.1 - 1.2 9.0 5.5 0.55 10.1 2.7 1.8 1 1 1 2 2 2 0 PCRF domain DUF4407 PF14362.6 AIM22607.1 - 2.8 7.2 8.8 5.4 6.3 8.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PspC PF04024.12 AIM22608.1 - 0.16 11.8 1.0 0.32 10.8 1.0 1.4 1 0 0 1 1 1 0 PspC domain Usher PF00577.20 AIM22610.1 - 1.5e-199 664.4 20.1 1.8e-199 664.2 20.1 1.0 1 0 0 1 1 1 1 Outer membrane usher protein PapC_N PF13954.6 AIM22610.1 - 7.8e-46 155.7 0.0 1.6e-45 154.7 0.0 1.5 1 0 0 1 1 1 1 PapC N-terminal domain PapC_C PF13953.6 AIM22610.1 - 5.8e-19 67.7 0.0 1.6e-18 66.3 0.0 1.8 1 0 0 1 1 1 1 PapC C-terminal domain PapD_N PF00345.20 AIM22611.1 - 2.8e-34 117.7 0.1 4.2e-34 117.1 0.1 1.3 1 0 0 1 1 1 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain PapD_C PF02753.17 AIM22611.1 - 8.6e-16 58.1 0.3 2.3e-15 56.7 0.1 1.8 2 0 0 2 2 2 1 Pili assembly chaperone PapD, C-terminal domain DUF4365 PF14280.6 AIM22611.1 - 0.034 14.1 0.0 0.056 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4365) DUF2362 PF10154.9 AIM22611.1 - 0.18 10.7 0.0 0.21 10.5 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) Fimbrial PF00419.20 AIM22612.1 - 2.7e-14 53.7 5.3 2.9e-14 53.6 5.3 1.0 1 0 0 1 1 1 1 Fimbrial protein FimA PF16970.5 AIM22612.1 - 0.00098 19.3 7.8 0.0076 16.4 2.0 2.1 1 1 1 2 2 2 2 Type-1 fimbrial protein, A PhoPQ_related PF10142.9 AIM22613.1 - 2e-81 273.5 0.0 2.3e-81 273.3 0.0 1.0 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein CelD_N PF02927.14 AIM22614.1 - 0.044 14.7 0.0 0.06 14.2 0.0 1.2 1 0 0 1 1 1 0 Cellulase N-terminal ig-like domain Staph_haemo PF05480.11 AIM22615.1 - 0.013 15.3 9.6 0.27 11.0 0.8 2.1 1 1 1 2 2 2 0 Staphylococcus haemolytic protein MccV PF17508.2 AIM22615.1 - 1.8 9.2 9.1 7.3 7.2 9.1 1.9 1 1 0 1 1 1 0 Microcin V bacteriocin RNA_capsid PF03035.14 AIM22615.1 - 5.4 7.0 9.4 3.4 7.6 2.1 2.0 1 1 1 2 2 2 0 Calicivirus putative RNA polymerase/capsid protein Hydrolase_3 PF08282.12 AIM22616.1 - 3.1e-52 177.8 0.0 3.5e-52 177.7 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 AIM22616.1 - 1.9e-10 40.7 0.0 2.8e-05 23.8 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 AIM22616.1 - 2.5e-06 27.9 1.1 0.34 11.2 0.0 3.3 2 2 1 3 3 3 3 haloacid dehalogenase-like hydrolase HAD PF12710.7 AIM22616.1 - 0.0017 18.8 2.9 2.5 8.5 0.0 3.4 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AIM22616.1 - 0.099 12.8 0.1 0.29 11.2 0.0 1.8 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase MAS20 PF02064.15 AIM22616.1 - 0.13 12.4 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 MAS20 protein import receptor Condensation PF00668.20 AIM22617.1 - 1.4e-119 399.8 0.0 7e-46 156.8 0.0 3.2 3 0 0 3 3 3 3 Condensation domain AMP-binding PF00501.28 AIM22617.1 - 8e-82 275.1 0.0 1.1e-81 274.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AIM22617.1 - 1.5e-10 41.9 0.1 3.9e-10 40.6 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 AIM22617.1 - 1.9e-09 37.7 0.0 5.5e-09 36.2 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Curto_V2 PF07325.11 AIM22618.1 - 0.051 13.5 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Curtovirus V2 protein GerE PF00196.19 AIM22619.1 - 4.7e-11 42.1 0.0 7.1e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4 PF04545.16 AIM22619.1 - 0.0061 16.0 0.0 0.013 15.1 0.0 1.6 1 1 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 AIM22619.1 - 0.02 14.6 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_3 PF01381.22 AIM22619.1 - 0.033 14.2 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix CENP-B_N PF04218.13 AIM22619.1 - 0.059 13.0 0.1 0.26 11.0 0.0 2.1 2 1 0 2 2 2 0 CENP-B N-terminal DNA-binding domain HTH_10 PF04967.12 AIM22619.1 - 0.13 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 HTH DNA binding domain HTH_38 PF13936.6 AIM22619.1 - 0.15 11.8 0.0 0.51 10.1 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain zinc_ribbon_2 PF13240.6 AIM22619.1 - 0.23 11.2 1.2 1.2 8.9 0.3 2.5 2 1 0 2 2 2 0 zinc-ribbon domain MccV PF17508.2 AIM22621.1 - 0.62 10.6 3.7 1.4 9.5 3.7 1.7 1 1 0 1 1 1 0 Microcin V bacteriocin Gemini_AL1_M PF08283.11 AIM22622.1 - 0.029 14.4 0.0 0.044 13.9 0.0 1.3 1 1 0 1 1 1 0 Geminivirus rep protein central domain PHA_synth_III_E PF09712.10 AIM22622.1 - 0.034 13.2 0.3 0.038 13.1 0.3 1.0 1 0 0 1 1 1 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) IcmF-related PF06761.12 AIM22623.1 - 1.2e-60 205.6 3.4 1.2e-60 205.6 3.4 1.8 2 0 0 2 2 2 1 Intracellular multiplication and human macrophage-killing IcmF_C PF06744.12 AIM22623.1 - 1.2e-52 178.5 0.1 2.1e-52 177.7 0.1 1.5 1 0 0 1 1 1 1 Type VI secretion protein IcmF C-terminal ImcF-related_N PF14331.6 AIM22623.1 - 6.8e-30 104.3 1.4 7.4e-30 104.2 0.1 1.7 2 0 0 2 2 2 1 ImcF-related N-terminal domain AAA_16 PF13191.6 AIM22623.1 - 0.013 15.9 0.0 0.062 13.7 0.0 2.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 AIM22623.1 - 0.051 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain DotU PF09850.9 AIM22624.1 - 1.9e-38 132.3 1.1 3.8e-38 131.3 1.1 1.5 1 0 0 1 1 1 1 Type VI secretion system protein DotU OmpA PF00691.20 AIM22624.1 - 1.9e-11 44.2 0.4 3.4e-11 43.4 0.4 1.4 1 0 0 1 1 1 1 OmpA family T6SS_VasE PF05936.12 AIM22625.1 - 3.9e-108 361.9 0.0 4.4e-108 361.7 0.0 1.0 1 0 0 1 1 1 1 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE T6SS-SciN PF12790.7 AIM22626.1 - 3.6e-10 39.6 0.0 5.8e-10 38.9 0.0 1.4 1 1 0 1 1 1 1 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 DUF4150 PF13665.6 AIM22627.1 - 2.8e-12 46.7 4.5 3.7e-12 46.4 4.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4150) PAAR_motif PF05488.13 AIM22627.1 - 0.024 14.8 2.5 0.21 11.8 2.5 2.3 1 1 0 1 1 1 0 PAAR motif DUF3540 PF12059.8 AIM22628.1 - 8.8e-21 74.6 5.9 2.1e-12 47.3 0.6 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3540) Pentapeptide_4 PF13599.6 AIM22629.1 - 4.9e-31 106.7 15.5 7.5e-10 38.8 4.0 4.9 1 1 3 4 4 4 4 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 AIM22629.1 - 3e-21 74.7 23.4 9.5e-06 25.1 0.8 7.4 4 2 2 7 7 7 6 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.6 AIM22629.1 - 1.4e-17 63.6 11.7 8.2e-05 22.7 1.7 6.5 5 2 2 7 7 7 5 Pentapeptide repeats (9 copies) CfAFP PF05264.11 AIM22629.1 - 0.064 13.2 4.0 0.16 11.9 2.8 2.2 2 1 0 2 2 2 0 Choristoneura fumiferana antifreeze protein (CfAFP) DUF2169 PF09937.9 AIM22630.1 - 6.7e-35 121.0 0.1 9.1e-35 120.5 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2169) Pentapeptide_4 PF13599.6 AIM22630.1 - 3.8e-33 113.5 21.5 5.8e-11 42.4 1.4 5.3 2 2 4 6 6 6 6 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 AIM22630.1 - 2.2e-20 71.9 30.2 2.7e-08 33.3 1.6 8.1 6 2 2 9 9 9 5 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.6 AIM22630.1 - 3.3e-16 59.2 29.6 2.2e-05 24.5 3.0 8.0 4 1 4 8 8 8 5 Pentapeptide repeats (9 copies) CfAFP PF05264.11 AIM22630.1 - 0.14 12.1 0.3 1.3 9.0 0.1 2.5 2 0 0 2 2 2 0 Choristoneura fumiferana antifreeze protein (CfAFP) Phage_GPD PF05954.11 AIM22631.1 - 2e-77 260.5 0.1 4.9e-77 259.2 0.1 1.7 1 0 0 1 1 1 1 Phage late control gene D protein (GPD) Phage_base_V PF04717.12 AIM22631.1 - 0.017 15.0 0.0 0.049 13.5 0.0 1.8 1 0 0 1 1 1 0 Type VI secretion system, phage-baseplate injector TGBp3 PF02495.17 AIM22631.1 - 0.63 9.8 6.2 3.5 7.4 6.2 2.4 1 0 0 1 1 1 0 Triple gene block 3 AAA_2 PF07724.14 AIM22632.1 - 2.6e-36 125.3 0.0 5.7e-35 120.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 AIM22632.1 - 8.5e-27 93.1 0.4 8.5e-27 93.1 0.4 3.0 2 1 1 3 3 3 1 AAA lid domain AAA PF00004.29 AIM22632.1 - 3.5e-19 69.5 0.1 5.3e-10 39.8 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AIM22632.1 - 3.6e-11 43.2 0.0 7.8e-07 29.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AIM22632.1 - 8.8e-10 39.2 10.5 3.5e-05 24.3 0.1 5.4 5 2 2 7 7 5 2 AAA ATPase domain ClpB_D2-small PF10431.9 AIM22632.1 - 9.2e-09 35.2 0.1 3.6e-08 33.3 0.1 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.20 AIM22632.1 - 7.3e-08 32.4 0.6 3e-06 27.3 0.0 3.3 3 0 0 3 3 3 1 Clp amino terminal domain, pathogenicity island component AAA_22 PF13401.6 AIM22632.1 - 5.2e-07 30.0 0.0 0.027 14.7 0.0 4.6 3 1 0 3 3 3 1 AAA domain Sigma54_activat PF00158.26 AIM22632.1 - 8.3e-07 28.9 0.1 0.0019 17.9 0.1 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.17 AIM22632.1 - 3.2e-06 27.0 0.0 0.036 13.8 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.6 AIM22632.1 - 1.1e-05 25.1 0.1 0.013 15.1 0.1 2.8 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 AIM22632.1 - 3.1e-05 23.9 0.5 0.012 15.5 0.0 3.5 3 1 0 3 3 3 1 NACHT domain ATPase_2 PF01637.18 AIM22632.1 - 5.7e-05 23.2 0.0 0.83 9.5 0.0 3.8 4 0 0 4 4 4 2 ATPase domain predominantly from Archaea AAA_18 PF13238.6 AIM22632.1 - 8.4e-05 23.1 0.3 0.16 12.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 AIM22632.1 - 0.00019 21.0 0.0 0.57 9.7 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region ResIII PF04851.15 AIM22632.1 - 0.00027 21.0 0.0 0.34 10.9 0.0 3.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 AIM22632.1 - 0.00064 20.1 0.0 1.4 9.4 0.0 3.0 3 0 0 3 3 2 1 RNA helicase CbiA PF01656.23 AIM22632.1 - 0.0013 18.8 0.1 0.52 10.4 0.0 3.0 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.12 AIM22632.1 - 0.0019 17.5 0.0 0.28 10.4 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin RuvB_N PF05496.12 AIM22632.1 - 0.0026 17.5 0.9 0.31 10.8 0.0 3.1 4 0 0 4 4 3 1 Holliday junction DNA helicase RuvB P-loop domain TniB PF05621.11 AIM22632.1 - 0.006 16.0 0.0 0.78 9.1 0.0 3.0 2 1 0 2 2 2 1 Bacterial TniB protein PhoH PF02562.16 AIM22632.1 - 0.0062 16.0 0.2 1.3 8.4 0.0 3.0 3 0 0 3 3 3 1 PhoH-like protein TIP49 PF06068.13 AIM22632.1 - 0.0078 15.5 0.2 4 6.6 0.0 3.1 2 1 1 3 3 3 1 TIP49 P-loop domain SRP54 PF00448.22 AIM22632.1 - 0.0089 15.7 0.2 3 7.4 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_6 PF12774.7 AIM22632.1 - 0.009 15.0 0.1 0.035 13.1 0.0 1.9 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region AAA_30 PF13604.6 AIM22632.1 - 0.0098 15.6 2.2 2.8 7.6 0.0 3.7 5 0 0 5 5 3 1 AAA domain AAA_23 PF13476.6 AIM22632.1 - 0.023 15.2 0.9 31 5.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 AIM22632.1 - 0.027 14.2 0.0 4.9 7.0 0.0 2.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain ArsA_ATPase PF02374.15 AIM22632.1 - 0.027 13.7 0.3 2.9 7.0 0.0 2.6 2 0 0 2 2 2 0 Anion-transporting ATPase RsgA_GTPase PF03193.16 AIM22632.1 - 0.027 14.4 0.0 3.7 7.4 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase EzrA PF06160.12 AIM22632.1 - 0.032 12.4 0.4 0.083 11.1 0.1 1.7 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Hpr_kinase_C PF07475.12 AIM22632.1 - 0.034 13.7 0.1 0.87 9.1 0.0 2.5 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Torsin PF06309.11 AIM22632.1 - 0.046 13.8 0.1 0.18 11.9 0.0 1.9 2 0 0 2 2 1 0 Torsin FAM167 PF11652.8 AIM22632.1 - 0.067 13.7 0.2 0.24 11.9 0.0 2.1 2 0 0 2 2 1 0 FAM167 AAA_28 PF13521.6 AIM22632.1 - 0.067 13.4 0.0 10 6.3 0.0 3.2 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 AIM22632.1 - 0.08 12.9 1.0 17 5.4 0.0 3.1 4 0 0 4 4 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 AIM22632.1 - 0.13 12.0 0.0 14 5.4 0.0 2.7 3 0 0 3 3 2 0 AAA domain ParA PF10609.9 AIM22632.1 - 0.19 11.1 0.2 14 5.0 0.0 2.4 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase AAA_33 PF13671.6 AIM22632.1 - 0.31 11.2 2.3 25 5.0 0.1 3.2 4 0 0 4 4 2 0 AAA domain DUF4140 PF13600.6 AIM22632.1 - 0.5 10.8 5.3 19 5.8 4.8 2.9 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) ABC_tran_CTD PF16326.5 AIM22632.1 - 2 8.7 7.5 1.2 9.5 2.7 2.8 1 1 1 2 2 2 0 ABC transporter C-terminal domain T6SS_TssF PF05947.12 AIM22633.1 - 2.6e-123 412.7 1.8 3.2e-123 412.4 1.8 1.0 1 0 0 1 1 1 1 Type VI secretion system, TssF GPW_gp25 PF04965.14 AIM22634.1 - 1.7e-12 46.9 0.0 2.3e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Gene 25-like lysozyme T6SS_HCP PF05638.12 AIM22635.1 - 9.8e-39 132.7 0.0 1.2e-38 132.5 0.0 1.1 1 0 0 1 1 1 1 Type VI secretion system effector, Hcp VipB PF05943.12 AIM22636.1 - 5.8e-181 601.9 0.0 6.8e-181 601.7 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion protein, EvpB/VC_A0108, tail sheath SurA_N_3 PF13624.6 AIM22636.1 - 0.11 12.3 1.5 0.21 11.3 1.1 1.7 1 1 1 2 2 2 0 SurA N-terminal domain T6SS_VipA PF05591.12 AIM22637.1 - 1.7e-54 183.8 0.9 2e-54 183.6 0.9 1.0 1 0 0 1 1 1 1 Type VI secretion system, VipA, VC_A0107 or Hcp2 GAT PF03127.14 AIM22637.1 - 0.022 15.1 0.3 3.8 7.9 0.0 2.3 2 0 0 2 2 2 0 GAT domain PRORP PF16953.5 AIM22637.1 - 0.12 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein-only RNase P ImpA_N PF06812.12 AIM22638.1 - 1.7e-11 44.3 0.0 3.1e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 ImpA, N-terminal, type VI secretion system HMMR_N PF15905.5 AIM22638.1 - 0.079 12.4 0.1 0.11 11.9 0.1 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal FH2 PF02181.23 AIM22638.1 - 0.15 11.2 0.6 0.67 9.0 0.2 2.0 1 1 1 2 2 2 0 Formin Homology 2 Domain DoxX PF07681.12 AIM22639.1 - 2.8e-16 59.9 10.3 2.8e-16 59.9 10.3 1.6 1 1 1 2 2 2 1 DoxX DoxD PF04173.13 AIM22639.1 - 0.0092 15.9 1.8 0.013 15.4 1.8 1.2 1 0 0 1 1 1 1 TQO small subunit DoxD DUF2162 PF09930.9 AIM22639.1 - 0.022 14.2 5.2 0.028 13.9 3.1 2.2 1 1 1 2 2 2 0 Predicted transporter (DUF2162) DoxX_2 PF13564.6 AIM22639.1 - 0.088 12.9 11.6 0.086 13.0 6.4 2.1 1 1 1 2 2 2 0 DoxX-like family HTH_39 PF14090.6 AIM22640.1 - 1.2e-06 28.1 0.3 5.9e-06 25.9 0.1 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain IclR PF01614.18 AIM22641.1 - 4.7e-31 107.3 0.2 7.8e-31 106.6 0.2 1.3 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 AIM22641.1 - 5.6e-15 54.9 0.1 5.6e-15 54.9 0.1 2.5 3 0 0 3 3 3 1 IclR helix-turn-helix domain Rrf2 PF02082.20 AIM22641.1 - 3.9e-06 27.1 0.0 1.9e-05 24.9 0.0 2.2 2 0 0 2 2 2 1 Transcriptional regulator TrmB PF01978.19 AIM22641.1 - 7.8e-05 22.5 0.0 0.00016 21.5 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 AIM22641.1 - 0.00011 22.0 0.1 0.00049 19.9 0.1 2.1 1 0 0 1 1 1 1 MarR family HTH_5 PF01022.20 AIM22641.1 - 0.00041 20.2 1.1 0.0066 16.3 0.0 2.8 3 0 0 3 3 3 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 AIM22641.1 - 0.0023 17.4 0.0 0.042 13.4 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 AIM22641.1 - 0.0041 17.0 0.1 0.058 13.3 0.0 2.5 2 0 0 2 2 2 1 HTH domain HTH_9 PF08221.11 AIM22641.1 - 0.0063 16.6 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 helix-turn-helix domain DUF4423 PF14394.6 AIM22641.1 - 0.0075 16.0 0.0 0.039 13.7 0.0 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4423) RP-C PF03428.13 AIM22641.1 - 0.013 15.2 0.0 0.031 13.9 0.0 1.6 2 0 0 2 2 2 0 Replication protein C N-terminal domain GntR PF00392.21 AIM22641.1 - 0.034 13.8 0.0 1.1 9.0 0.0 3.0 3 0 0 3 3 3 0 Bacterial regulatory proteins, gntR family RPA_C PF08784.11 AIM22641.1 - 0.082 13.6 0.0 0.23 12.1 0.0 1.7 1 0 0 1 1 1 0 Replication protein A C terminal HTH_23 PF13384.6 AIM22641.1 - 0.11 12.4 0.1 0.76 9.7 0.1 2.2 2 0 0 2 2 2 0 Homeodomain-like domain CoA_trans PF01144.23 AIM22642.1 - 3.8e-66 222.6 0.0 4.3e-66 222.4 0.0 1.0 1 0 0 1 1 1 1 Coenzyme A transferase KR PF08659.10 AIM22642.1 - 0.074 13.0 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 KR domain CoA_trans PF01144.23 AIM22643.1 - 1.8e-34 119.1 0.0 2e-34 118.9 0.0 1.0 1 0 0 1 1 1 1 Coenzyme A transferase CRAM_rpt PF07016.11 AIM22643.1 - 0.2 11.5 0.2 0.39 10.5 0.2 1.4 1 0 0 1 1 1 0 Cysteine-rich acidic integral membrane protein precursor Thiolase_N PF00108.23 AIM22644.1 - 7.9e-72 241.7 0.0 1.1e-71 241.3 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 AIM22644.1 - 5e-44 148.9 0.9 8.6e-44 148.1 0.9 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 AIM22644.1 - 1.2e-05 25.1 0.2 2.9e-05 23.8 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Lyase_1 PF00206.20 AIM22645.1 - 5.4e-49 167.3 0.0 8e-49 166.7 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 AIM22645.1 - 4.4e-19 68.8 1.3 1e-18 67.6 0.1 2.3 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus LysR_substrate PF03466.20 AIM22646.1 - 1.9e-26 92.7 7.6 2.3e-26 92.5 7.6 1.1 1 0 0 1 1 1 1 LysR substrate binding domain Dioxygenase_C PF00775.21 AIM22647.1 - 7.5e-20 71.1 0.0 6.5e-19 68.1 0.0 1.9 1 1 0 1 1 1 1 Dioxygenase Dioxygenase_C PF00775.21 AIM22648.1 - 8.9e-55 184.9 0.0 1.1e-54 184.6 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase PCDO_beta_N PF12391.8 AIM22648.1 - 5e-14 51.6 2.9 9.8e-14 50.7 2.9 1.5 1 0 0 1 1 1 1 Protocatechuate 3,4-dioxygenase beta subunit N terminal CarboxypepD_reg PF13620.6 AIM22648.1 - 5.1e-06 26.7 0.0 2.1e-05 24.7 0.0 1.9 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain AP_endonuc_2 PF01261.24 AIM22649.1 - 1.2e-36 126.2 0.0 4.2e-36 124.4 0.0 1.9 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel Glyoxalase_5 PF14696.6 AIM22649.1 - 4.4e-25 88.5 0.0 8.6e-25 87.5 0.0 1.4 1 0 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_4 PF13669.6 AIM22649.1 - 7.7e-08 32.6 0.0 0.019 15.2 0.0 2.7 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 AIM22649.1 - 6.5e-06 26.4 0.0 0.00012 22.3 0.0 2.4 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily MFS_1 PF07690.16 AIM22650.1 - 2.6e-49 168.0 69.9 2.1e-46 158.5 45.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AIM22650.1 - 4.3e-26 91.8 29.0 2.9e-23 82.5 7.9 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 AIM22650.1 - 4.7e-10 39.3 32.2 8.5e-09 35.2 10.3 2.1 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB UPF0227 PF05728.12 AIM22650.1 - 0.00036 20.5 0.4 0.76 9.7 0.1 2.5 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0227) MFS_1_like PF12832.7 AIM22650.1 - 0.00055 18.9 14.6 0.059 12.2 0.6 2.6 2 0 0 2 2 2 2 MFS_1 like family EMP70 PF02990.16 AIM22650.1 - 0.42 9.2 3.3 0.74 8.4 3.3 1.5 1 0 0 1 1 1 0 Endomembrane protein 70 DUF4381 PF14316.6 AIM22650.1 - 6 7.1 6.4 3 8.1 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Peptidase_M90 PF06167.12 AIM22651.1 - 5.4e-65 219.4 0.0 6.6e-65 219.1 0.0 1.0 1 0 0 1 1 1 1 Glucose-regulated metallo-peptidase M90 Gp_dh_C PF02800.20 AIM22652.1 - 2.6e-60 202.6 0.0 3.7e-60 202.1 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 AIM22652.1 - 1.7e-38 131.0 0.0 5.5e-38 129.4 0.0 1.9 3 0 0 3 3 3 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 AIM22652.1 - 0.00018 21.6 0.3 0.0014 18.8 0.3 2.3 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 AIM22652.1 - 0.0054 16.1 0.0 0.0086 15.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HTH_18 PF12833.7 AIM22653.1 - 3.5e-20 72.1 0.6 3.5e-20 72.1 0.6 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain DJ-1_PfpI PF01965.24 AIM22653.1 - 2.8e-19 69.5 0.0 4.4e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family HTH_AraC PF00165.23 AIM22653.1 - 3.8e-17 61.9 0.0 2.4e-09 37.0 0.0 2.5 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family adh_short PF00106.25 AIM22654.1 - 1.4e-14 54.0 0.1 1.1e-13 51.1 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AIM22654.1 - 5.7e-09 35.9 0.2 5.9e-08 32.5 0.2 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AIM22654.1 - 9.3e-06 25.7 0.1 1.6e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 AIM22654.1 - 2.9e-05 24.0 0.1 4e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 AIM22654.1 - 0.0002 20.9 0.0 0.0004 19.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ZNRF_3_ecto PF18212.1 AIM22654.1 - 0.2 11.6 0.0 0.34 10.9 0.0 1.3 1 0 0 1 1 1 0 ZNRF-3 Ectodomain NmrA PF05368.13 AIM22654.1 - 0.24 10.9 0.2 0.34 10.4 0.2 1.2 1 0 0 1 1 1 0 NmrA-like family Bac_luciferase PF00296.20 AIM22655.1 - 8.2e-25 87.9 3.7 1.2e-24 87.3 3.7 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase TENA_THI-4 PF03070.16 AIM22656.1 - 4.3e-46 157.4 0.0 4.8e-46 157.2 0.0 1.0 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Haem_oxygenas_2 PF14518.6 AIM22656.1 - 0.11 12.3 2.1 1 9.1 1.5 2.5 1 1 1 2 2 2 0 Iron-containing redox enzyme ABC_tran PF00005.27 AIM22657.1 - 3e-24 86.1 0.0 4.5e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIM22657.1 - 2.6e-08 34.0 0.9 0.0014 18.5 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 AIM22657.1 - 0.00024 21.0 0.1 0.0005 20.0 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 AIM22657.1 - 0.0003 20.3 0.4 0.012 15.0 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AIM22657.1 - 0.00042 20.7 2.0 0.0012 19.2 2.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 AIM22657.1 - 0.0092 15.7 1.8 0.033 13.9 1.8 1.9 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 AIM22657.1 - 0.083 13.3 0.2 0.27 11.6 0.2 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 AIM22657.1 - 0.11 12.3 0.5 0.21 11.3 0.5 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 AIM22657.1 - 0.19 11.6 1.2 0.52 10.2 0.3 2.0 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 AIM22657.1 - 0.28 11.4 1.3 1.3 9.3 0.4 2.1 2 1 0 2 2 2 0 AAA domain BPD_transp_1 PF00528.22 AIM22658.1 - 5.6e-27 94.7 18.9 5.6e-27 94.7 18.9 1.6 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Shadoo PF14999.6 AIM22658.1 - 4 7.6 7.9 1.4 9.0 2.9 2.0 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective NMT1 PF09084.11 AIM22659.1 - 2.1e-68 230.5 0.1 2.5e-68 230.2 0.1 1.1 1 0 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.20 AIM22659.1 - 1.3e-07 31.3 0.3 1.2e-06 28.1 0.2 2.4 1 1 1 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.7 AIM22659.1 - 0.0077 15.9 0.1 0.43 10.1 0.0 2.4 1 1 1 2 2 2 2 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1_3 PF16868.5 AIM22659.1 - 0.013 15.0 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 NMT1-like family NMT1_2 PF13379.6 AIM22659.1 - 0.02 14.6 0.1 0.14 11.8 0.1 2.0 1 1 0 1 1 1 0 NMT1-like family YhfZ_C PF14503.6 AIM22659.1 - 0.078 12.5 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 YhfZ C-terminal domain SBP_bac_3 PF00497.20 AIM22660.1 - 1.8e-22 79.9 0.1 2.2e-22 79.6 0.1 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Sulfatase PF00884.23 AIM22661.1 - 1.6e-25 90.2 0.1 2.2e-25 89.7 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Glucos_trans_II PF14264.6 AIM22661.1 - 0.064 12.6 10.4 0.1 12.0 10.4 1.3 1 0 0 1 1 1 0 Glucosyl transferase GtrII Wzy_C PF04932.15 AIM22661.1 - 1 9.0 7.1 2 8.0 0.0 2.3 2 0 0 2 2 2 0 O-Antigen ligase AMNp_N PF10423.9 AIM22662.1 - 2.2e-55 186.6 0.1 4.2e-55 185.6 0.1 1.4 1 0 0 1 1 1 1 Bacterial AMP nucleoside phosphorylase N-terminus PNP_UDP_1 PF01048.20 AIM22662.1 - 9e-20 70.9 0.0 3.8e-19 68.9 0.0 1.8 2 0 0 2 2 2 1 Phosphorylase superfamily LysR_substrate PF03466.20 AIM22663.1 - 4e-28 98.2 2.7 5e-28 97.9 2.7 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM22663.1 - 2.4e-22 78.6 0.4 5.1e-22 77.6 0.4 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_5 PF01022.20 AIM22663.1 - 0.092 12.6 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family DMT_YdcZ PF04657.13 AIM22664.1 - 3.4e-19 69.5 20.2 3.8e-19 69.3 20.2 1.0 1 0 0 1 1 1 1 Putative inner membrane exporter, YdcZ TM_helix PF05552.12 AIM22664.1 - 0.62 10.1 0.1 0.62 10.1 0.1 3.0 3 1 0 3 3 3 0 Conserved TM helix Acetyltransf_4 PF13420.7 AIM22665.1 - 3.8e-21 75.8 0.0 4.3e-21 75.7 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AIM22665.1 - 3.2e-16 59.6 0.3 3.9e-16 59.4 0.3 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 AIM22665.1 - 5.8e-12 46.5 0.5 6.9e-12 46.2 0.5 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AIM22665.1 - 5.8e-08 32.7 0.1 7.8e-08 32.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AIM22665.1 - 3.9e-07 30.4 0.1 5.9e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AIM22665.1 - 4e-07 29.9 0.2 1.6e-06 28.0 0.2 1.8 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.6 AIM22665.1 - 0.00017 21.6 0.1 0.00028 21.0 0.1 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase GNAT_acetyltran PF12746.7 AIM22665.1 - 0.075 12.6 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase EAL PF00563.20 AIM22665.1 - 0.12 11.8 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 EAL domain HTH_3 PF01381.22 AIM22666.1 - 1.5e-13 50.6 0.0 2.2e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 AIM22666.1 - 1.4e-10 41.4 1.8 2.3e-10 40.6 1.8 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 AIM22666.1 - 3.9e-08 33.2 0.0 6.2e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Cupin_2 PF07883.11 AIM22666.1 - 8.2e-06 25.4 0.0 1.5e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Cupin domain HTH_25 PF13413.6 AIM22666.1 - 5.1e-05 23.1 0.2 0.00014 21.6 0.2 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_26 PF13443.6 AIM22666.1 - 0.00057 20.3 0.0 0.001 19.5 0.0 1.4 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_IclR PF09339.10 AIM22666.1 - 0.0018 18.1 0.6 0.013 15.2 0.0 2.4 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_37 PF13744.6 AIM22666.1 - 0.0031 17.4 0.0 0.006 16.5 0.0 1.5 1 1 0 1 1 1 1 Helix-turn-helix domain TetR_N PF00440.23 AIM22666.1 - 0.015 15.0 0.1 0.25 11.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family HTH_6 PF01418.17 AIM22666.1 - 0.018 15.0 0.0 0.031 14.3 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family Sigma70_r4 PF04545.16 AIM22666.1 - 0.029 13.9 0.2 0.054 13.0 0.2 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_11 PF08279.12 AIM22666.1 - 0.043 13.8 0.0 0.096 12.7 0.0 1.5 1 0 0 1 1 1 0 HTH domain DUF2623 PF11115.8 AIM22667.1 - 3.3e-32 110.4 0.6 3.6e-32 110.3 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2623) Nitroreductase PF00881.24 AIM22668.1 - 4.9e-18 65.8 1.7 6.1e-09 36.2 0.2 2.1 1 1 1 2 2 2 2 Nitroreductase family TM1586_NiRdase PF14512.6 AIM22668.1 - 1.7e-06 27.8 0.0 0.0014 18.2 0.0 2.1 2 0 0 2 2 2 2 Putative TM nitroreductase LysR_substrate PF03466.20 AIM22669.1 - 8.4e-29 100.4 6.4 1.3e-28 99.8 6.4 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM22669.1 - 6.8e-20 70.8 1.3 2.8e-19 68.8 1.0 2.0 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family Flavodoxin_2 PF02525.17 AIM22670.1 - 1.3e-18 67.5 0.0 1.6e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 AIM22670.1 - 3.3e-17 62.7 0.0 3.9e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase NAD_binding_9 PF13454.6 AIM22672.1 - 9.2e-32 110.2 1.3 3.9e-31 108.2 0.3 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 AIM22672.1 - 3.9e-08 33.4 0.6 6e-07 29.6 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AIM22672.1 - 4.7e-08 32.6 0.0 8.5e-08 31.8 0.0 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AIM22672.1 - 1.2e-07 31.6 3.4 2.3e-07 30.7 3.4 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 AIM22672.1 - 2.4e-05 24.8 1.4 8.9e-05 23.0 0.4 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 AIM22672.1 - 6.8e-05 22.2 0.2 0.016 14.3 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 AIM22672.1 - 0.012 14.5 0.1 0.016 14.0 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Lycopene_cycl PF05834.12 AIM22672.1 - 0.019 14.1 0.2 0.044 12.8 0.2 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.22 AIM22672.1 - 0.022 13.9 0.2 0.075 12.1 0.5 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 AIM22672.1 - 0.028 13.5 3.4 0.024 13.7 1.9 1.6 1 1 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.19 AIM22672.1 - 0.042 13.1 1.0 0.069 12.4 1.0 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 AIM22672.1 - 0.043 12.5 0.5 0.077 11.7 0.5 1.3 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 AIM22672.1 - 0.06 12.6 0.4 0.099 11.9 0.4 1.2 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.18 AIM22672.1 - 0.11 12.8 0.1 0.23 11.7 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain FAD_oxidored PF12831.7 AIM22672.1 - 0.11 11.8 0.9 0.15 11.4 0.9 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 AIM22672.1 - 0.15 12.5 0.0 0.2 12.1 0.0 1.5 1 1 0 1 1 1 0 Putative NAD(P)-binding Bac_luciferase PF00296.20 AIM22673.1 - 1.1e-86 291.2 2.5 1.5e-86 290.7 2.5 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Sigma54_activat PF00158.26 AIM22674.1 - 1.2e-65 220.4 0.0 2.2e-65 219.5 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AIM22674.1 - 2.6e-20 73.0 0.0 5.5e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain NMT1 PF09084.11 AIM22674.1 - 8.3e-13 48.8 0.0 1.3e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like AAA_5 PF07728.14 AIM22674.1 - 2.8e-08 33.8 0.1 7.9e-08 32.4 0.0 1.8 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) HTH_8 PF02954.19 AIM22674.1 - 1.1e-06 28.3 1.5 3.7e-06 26.6 0.4 2.4 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family Phosphonate-bd PF12974.7 AIM22674.1 - 2.5e-05 24.0 0.0 4.4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 AIM22674.1 - 0.00032 20.2 0.0 0.0006 19.3 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 AAA PF00004.29 AIM22674.1 - 0.0015 19.0 0.0 0.0034 17.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 AIM22674.1 - 0.0029 17.2 0.0 0.0056 16.2 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region HTH_30 PF13556.6 AIM22674.1 - 0.0031 17.3 0.2 0.01 15.6 0.2 1.9 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain AAA_2 PF07724.14 AIM22674.1 - 0.0075 16.4 0.0 0.021 14.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 AIM22674.1 - 0.0095 16.3 1.1 0.0095 16.3 1.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain HTH_17 PF12728.7 AIM22674.1 - 0.013 15.7 0.1 0.047 13.9 0.1 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_20 PF12840.7 AIM22674.1 - 0.013 15.5 0.3 0.11 12.6 0.2 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain AAA_22 PF13401.6 AIM22674.1 - 0.025 14.9 0.1 0.14 12.4 0.0 2.4 2 1 0 2 2 2 0 AAA domain MerR PF00376.23 AIM22674.1 - 0.067 13.0 0.1 0.19 11.6 0.1 1.7 1 0 0 1 1 1 0 MerR family regulatory protein MCM PF00493.23 AIM22674.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain AAA_3 PF07726.11 AIM22674.1 - 0.16 11.9 0.0 0.39 10.6 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HTH_18 PF12833.7 AIM22675.1 - 2e-19 69.7 0.2 3.3e-19 68.9 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AIM22675.1 - 1.2e-08 34.9 1.6 2.8e-06 27.3 0.2 2.3 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family PBECR1 PF18809.1 AIM22675.1 - 0.2 12.3 0.3 1.3 9.7 0.0 2.2 2 1 1 3 3 3 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease1 HTH_18 PF12833.7 AIM22676.1 - 4.8e-19 68.4 0.7 6.8e-19 67.9 0.7 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AIM22676.1 - 1e-16 60.5 1.6 3.3e-08 33.4 0.4 2.2 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_41 PF14502.6 AIM22676.1 - 0.0067 16.1 0.0 0.022 14.5 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain DUF4809 PF16067.5 AIM22676.1 - 0.17 12.0 0.1 0.33 11.1 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4809) GyrI-like PF06445.15 AIM22677.1 - 0.0021 18.4 0.0 0.0031 17.8 0.0 1.2 1 0 0 1 1 1 1 GyrI-like small molecule binding domain Cass2 PF14526.6 AIM22677.1 - 0.041 14.0 0.0 0.064 13.4 0.0 1.3 1 0 0 1 1 1 0 Integron-associated effector binding protein MFS_5 PF05631.14 AIM22677.1 - 0.14 11.1 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Sugar-tranasporters, 12 TM PQQ PF01011.21 AIM22678.1 - 1.6e-33 113.0 7.0 7e-06 25.7 0.0 7.4 8 0 0 8 8 8 6 PQQ enzyme repeat PQQ_2 PF13360.6 AIM22678.1 - 7.1e-20 71.6 0.1 1.7e-08 34.3 0.0 3.9 2 2 1 3 3 3 3 PQQ-like domain PQQ_3 PF13570.6 AIM22678.1 - 9.5e-13 48.2 13.1 0.19 12.2 0.3 8.4 7 0 0 7 7 7 5 PQQ-like domain Na_H_Exchanger PF00999.21 AIM22679.1 - 3.8e-71 239.9 48.1 4.7e-71 239.6 48.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Glycos_transf_2 PF00535.26 AIM22680.1 - 8.9e-18 64.7 0.0 1.2e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_4 PF13704.6 AIM22680.1 - 6.9e-07 29.7 0.2 1.4e-06 28.7 0.2 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AIM22680.1 - 6.6e-05 22.9 0.0 0.0001 22.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 AIM22680.1 - 0.019 14.5 0.1 0.069 12.6 0.1 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 21 tRNA_SAD PF07973.14 AIM22682.1 - 2.9e-05 24.1 0.1 4.9e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.19 AIM22682.1 - 0.0014 17.2 0.0 0.0017 16.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) LysR_substrate PF03466.20 AIM22683.1 - 2.5e-42 144.6 1.8 3.8e-42 144.0 1.8 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM22683.1 - 6.5e-19 67.6 2.7 1.5e-18 66.5 2.7 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_Tnp_ISL3 PF13542.6 AIM22683.1 - 0.00042 19.7 0.3 0.0016 17.8 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 MarR_2 PF12802.7 AIM22683.1 - 0.0025 17.7 0.1 0.0081 16.0 0.1 1.8 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 AIM22683.1 - 0.03 13.9 0.0 0.063 12.9 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 AIM22683.1 - 0.037 13.8 0.1 0.096 12.5 0.1 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_28 PF13518.6 AIM22683.1 - 0.12 12.5 0.0 0.37 10.9 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain EamA PF00892.20 AIM22684.1 - 1.2e-08 35.3 25.7 5.7e-07 29.8 8.1 2.2 2 0 0 2 2 2 2 EamA-like transporter family adh_short_C2 PF13561.6 AIM22685.1 - 2.6e-57 194.1 0.0 3.9e-57 193.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AIM22685.1 - 1.9e-49 167.8 0.0 4.3e-49 166.6 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AIM22685.1 - 1.5e-11 44.5 0.8 3.1e-09 37.0 0.8 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 AIM22685.1 - 1.3e-05 24.8 0.0 2e-05 24.2 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 AIM22685.1 - 0.00037 19.7 0.0 0.00052 19.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Chorismate_bind PF00425.18 AIM22686.1 - 8.9e-76 254.8 0.0 1.1e-75 254.6 0.0 1.1 1 0 0 1 1 1 1 chorismate binding enzyme 4PPT_N PF17837.1 AIM22687.1 - 8.7e-22 77.0 1.6 3.3e-21 75.2 0.4 2.1 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase N-terminal domain ACPS PF01648.20 AIM22687.1 - 1.3e-11 44.6 0.0 2.1e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily DUF86 PF01934.17 AIM22688.1 - 1.9e-23 82.6 0.0 2.6e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF86 Polbeta PF18765.1 AIM22689.1 - 1.1e-07 31.8 0.0 1.4e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 AIM22689.1 - 9.4e-07 29.0 0.0 9.7e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyltransferase domain UBM PF14377.6 AIM22689.1 - 0.0085 15.5 1.9 0.052 13.0 0.6 2.4 2 0 0 2 2 2 1 Ubiquitin binding region His_Phos_2 PF00328.22 AIM22690.1 - 1.5e-19 70.6 0.0 2.8e-18 66.4 0.0 2.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Na_sulph_symp PF00939.19 AIM22691.1 - 8.1e-173 575.8 37.6 9.7e-173 575.5 37.6 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 AIM22691.1 - 1.5e-19 70.4 53.4 1.8e-12 47.1 28.2 2.4 1 1 1 2 2 2 2 Citrate transporter CitG PF01874.16 AIM22692.1 - 3.5e-85 286.1 3.6 3.9e-85 285.9 3.6 1.0 1 0 0 1 1 1 1 ATP:dephospho-CoA triphosphoribosyl transferase YwqJ-deaminase PF14431.6 AIM22692.1 - 0.0054 16.9 0.0 0.0091 16.2 0.0 1.3 1 0 0 1 1 1 1 YwqJ-like deaminase UreF PF01730.16 AIM22692.1 - 0.018 15.6 0.4 0.038 14.6 0.4 1.6 1 0 0 1 1 1 0 UreF CitX PF03802.14 AIM22693.1 - 2.8e-52 176.8 0.0 3.2e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase CitF PF04223.12 AIM22694.1 - 4e-255 846.9 0.5 4.6e-255 846.7 0.5 1.0 1 0 0 1 1 1 1 Citrate lyase, alpha subunit (CitF) AcetylCoA_hyd_C PF13336.6 AIM22694.1 - 0.028 14.4 0.0 0.053 13.5 0.0 1.4 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain HpcH_HpaI PF03328.14 AIM22695.1 - 1.9e-80 269.2 0.8 1.9e-80 269.2 0.8 1.5 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 AIM22695.1 - 2.4e-10 40.1 0.0 9.5e-08 31.6 0.0 2.2 2 1 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold ACP PF06857.11 AIM22696.1 - 1.7e-28 98.6 0.1 2.1e-28 98.4 0.1 1.1 1 0 0 1 1 1 1 Malonate decarboxylase delta subunit (MdcD) DUF4242 PF14026.6 AIM22696.1 - 0.028 14.6 0.0 0.038 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4242) Orn_Arg_deC_N PF02784.16 AIM22696.1 - 0.056 12.8 0.0 0.072 12.4 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Citrate_ly_lig PF08218.11 AIM22697.1 - 9e-77 256.9 0.0 1.2e-76 256.5 0.0 1.2 1 0 0 1 1 1 1 Citrate lyase ligase C-terminal domain Acetyltransf_1 PF00583.25 AIM22697.1 - 9.6e-05 22.6 0.0 0.00026 21.2 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AIM22697.1 - 0.00012 22.0 0.0 0.00021 21.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain HIGH_NTase1 PF05636.11 AIM22697.1 - 0.0048 16.2 0.0 1.1 8.4 0.0 2.1 2 0 0 2 2 2 2 HIGH Nucleotidyl Transferase FR47 PF08445.10 AIM22697.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Response_reg PF00072.24 AIM22698.1 - 3.2e-20 72.3 0.0 5e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain CitT PF12431.8 AIM22698.1 - 2.5e-06 27.7 0.0 5.3e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulator HTH_23 PF13384.6 AIM22698.1 - 0.02 14.7 0.6 0.057 13.2 0.1 2.0 2 0 0 2 2 2 0 Homeodomain-like domain HTH_24 PF13412.6 AIM22698.1 - 0.02 14.4 0.1 0.18 11.4 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Dimerisation2 PF16864.5 AIM22698.1 - 0.029 14.4 0.1 0.35 10.9 0.0 2.2 2 0 0 2 2 2 0 Dimerisation domain HTH_IclR PF09339.10 AIM22698.1 - 0.036 13.9 0.3 0.089 12.6 0.3 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_11 PF08279.12 AIM22698.1 - 0.04 13.9 0.0 0.074 13.0 0.0 1.5 1 0 0 1 1 1 0 HTH domain HTH_10 PF04967.12 AIM22698.1 - 0.042 13.7 0.2 0.53 10.1 0.0 2.2 2 0 0 2 2 2 0 HTH DNA binding domain HTH_29 PF13551.6 AIM22698.1 - 0.046 13.7 1.0 0.21 11.6 0.1 2.2 2 0 0 2 2 2 0 Winged helix-turn helix Glyco_hydro_2_C PF02836.17 AIM22699.1 - 6.4e-117 390.0 0.0 8.4e-117 389.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 AIM22699.1 - 1.4e-62 210.6 0.0 4.1e-62 209.0 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Bgal_small_N PF02929.17 AIM22699.1 - 6.3e-57 193.0 0.0 9.5e-57 192.4 0.0 1.3 1 0 0 1 1 1 1 Beta galactosidase small chain DUF4981 PF16353.5 AIM22699.1 - 8.1e-18 64.7 0.0 2.2e-17 63.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 AIM22699.1 - 3.2e-13 50.3 0.0 5.3e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 MdcG PF10620.9 AIM22699.1 - 0.045 13.5 2.1 0.22 11.3 0.4 2.5 2 0 0 2 2 2 0 Phosphoribosyl-dephospho-CoA transferase MdcG adh_short PF00106.25 AIM22700.1 - 4.1e-48 163.4 0.0 5.4e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AIM22700.1 - 2.3e-36 125.5 0.0 2.9e-36 125.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 AIM22700.1 - 3e-05 24.0 0.3 6.2e-05 23.0 0.2 1.6 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 AIM22700.1 - 0.00011 22.2 0.0 0.00018 21.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AIM22700.1 - 0.013 15.0 0.1 0.022 14.2 0.1 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 AIM22700.1 - 0.015 15.3 0.1 0.022 14.7 0.1 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF1776 PF08643.10 AIM22700.1 - 0.12 11.7 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 AIM22700.1 - 0.18 10.9 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Flavin_Reduct PF01613.18 AIM22701.1 - 6.2e-08 32.8 0.0 8e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain LysR_substrate PF03466.20 AIM22702.1 - 3.1e-16 59.4 0.0 4.5e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM22702.1 - 9.7e-14 51.1 0.1 1.6e-13 50.4 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family Trep_Strep PF09605.10 AIM22705.1 - 1.4 8.8 11.3 0.046 13.7 3.4 2.3 2 1 1 3 3 3 0 Hypothetical bacterial integral membrane protein (Trep_Strep) ThrE PF06738.12 AIM22705.1 - 3.1 7.1 14.6 0.1 11.9 8.1 1.8 1 1 0 2 2 2 0 Putative threonine/serine exporter Autoind_bind PF03472.15 AIM22706.1 - 1.1e-16 60.6 0.5 2.3e-16 59.6 0.2 1.7 2 0 0 2 2 2 1 Autoinducer binding domain GerE PF00196.19 AIM22706.1 - 3.9e-16 58.3 0.1 5.9e-16 57.8 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AIM22706.1 - 4.3e-08 32.7 0.4 8.9e-08 31.7 0.4 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AIM22706.1 - 1.9e-05 24.1 1.5 4.8e-05 22.8 1.5 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 AIM22706.1 - 0.00019 21.2 2.3 0.00027 20.6 1.1 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_10 PF04967.12 AIM22706.1 - 0.00089 19.0 0.0 0.0023 17.7 0.0 1.7 1 0 0 1 1 1 1 HTH DNA binding domain HTH_28 PF13518.6 AIM22706.1 - 0.0011 19.1 1.6 0.0025 17.9 1.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain Terminase_5 PF06056.12 AIM22706.1 - 0.0043 16.9 0.0 0.0095 15.8 0.0 1.6 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) HTH_29 PF13551.6 AIM22706.1 - 0.006 16.6 0.2 0.014 15.4 0.2 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_38 PF13936.6 AIM22706.1 - 0.0064 16.2 1.1 0.015 15.1 1.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_30 PF13556.6 AIM22706.1 - 0.011 15.6 0.7 0.029 14.2 0.7 1.8 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_Crp_2 PF13545.6 AIM22706.1 - 0.035 14.1 0.2 0.066 13.2 0.2 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_24 PF13412.6 AIM22706.1 - 0.044 13.3 0.1 0.11 12.1 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 AIM22706.1 - 0.061 13.2 0.3 0.22 11.4 0.3 2.1 1 1 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_11 PF08279.12 AIM22706.1 - 0.068 13.1 0.2 0.14 12.2 0.2 1.4 1 0 0 1 1 1 0 HTH domain HTH_5 PF01022.20 AIM22706.1 - 0.086 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Sigma70_ECF PF07638.11 AIM22706.1 - 0.088 12.7 0.6 0.13 12.1 0.6 1.2 1 0 0 1 1 1 0 ECF sigma factor Trans_reg_C PF00486.28 AIM22706.1 - 0.12 12.5 0.3 0.28 11.3 0.3 1.8 1 1 0 1 1 1 0 Transcriptional regulatory protein, C terminal HU-CCDC81_euk_2 PF18289.1 AIM22706.1 - 0.18 12.0 0.1 0.35 11.1 0.1 1.5 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 2 HTH_40 PF14493.6 AIM22706.1 - 0.2 12.1 0.0 0.4 11.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain DJ-1_PfpI PF01965.24 AIM22707.1 - 2e-09 37.5 0.0 6.4e-09 35.8 0.0 1.8 2 1 0 2 2 2 1 DJ-1/PfpI family DUF3898 PF13037.6 AIM22707.1 - 0.16 12.1 0.1 59 3.9 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3898) ABC_tran PF00005.27 AIM22708.1 - 1.4e-22 80.7 0.0 2.6e-22 79.8 0.0 1.4 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.6 AIM22708.1 - 1.9e-12 47.6 0.0 1.7e-06 28.1 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIM22708.1 - 4.8e-07 29.4 0.4 0.00046 19.7 0.2 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AIM22708.1 - 0.00021 21.6 0.6 0.17 12.1 0.1 2.2 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 AIM22708.1 - 0.0004 20.2 0.0 0.13 11.9 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_16 PF13191.6 AIM22708.1 - 0.00081 19.8 0.0 0.0011 19.4 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 AIM22708.1 - 0.0021 18.6 0.1 0.0034 17.9 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AIM22708.1 - 0.0089 15.8 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.12 AIM22708.1 - 0.019 14.9 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 AIM22708.1 - 0.026 14.2 0.1 0.078 12.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 AIM22708.1 - 0.042 13.4 0.1 0.077 12.6 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_13 PF13166.6 AIM22708.1 - 0.043 12.5 0.0 0.75 8.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 AIM22708.1 - 0.063 13.0 0.1 11 5.7 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_25 PF13481.6 AIM22708.1 - 0.063 12.8 0.0 0.51 9.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 AIM22708.1 - 0.071 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase ATPase_2 PF01637.18 AIM22708.1 - 0.075 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 AIM22708.1 - 0.1 13.0 0.1 0.63 10.5 0.0 2.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 AIM22708.1 - 0.11 12.9 0.3 0.36 11.2 0.3 2.0 1 1 0 1 1 1 0 AAA domain AAA_27 PF13514.6 AIM22708.1 - 0.14 11.8 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AIM22708.1 - 0.19 11.9 0.0 0.49 10.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 AIM22708.1 - 0.27 11.5 0.7 1.1 9.4 0.1 2.1 2 1 0 2 2 2 0 AAA domain FecCD PF01032.18 AIM22709.1 - 8.8e-83 277.9 33.0 1.1e-82 277.5 33.0 1.0 1 0 0 1 1 1 1 FecCD transport family ABC-3 PF00950.17 AIM22709.1 - 1.2e-07 31.5 18.5 1.2e-07 31.5 18.5 1.6 2 1 0 2 2 2 1 ABC 3 transport family BPD_transp_2 PF02653.16 AIM22709.1 - 0.0099 15.1 32.1 0.05 12.8 32.1 2.2 1 1 0 1 1 1 1 Branched-chain amino acid transport system / permease component B12D PF06522.11 AIM22709.1 - 5.7 6.8 5.9 5.9 6.8 0.3 3.3 3 0 0 3 3 3 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Peripla_BP_2 PF01497.18 AIM22710.1 - 5.5e-17 62.1 0.0 8.3e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein TPPK_C PF12555.8 AIM22711.1 - 0.08 13.0 1.9 0.08 13.0 0.5 1.7 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal DUF3040 PF11239.8 AIM22711.1 - 6.1 7.2 6.5 12 6.2 6.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) MFS_1 PF07690.16 AIM22712.1 - 1.9e-44 152.1 42.4 1.9e-44 152.1 42.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 AIM22712.1 - 1.1e-08 34.4 30.0 1e-06 27.9 13.6 3.3 2 1 1 3 3 3 3 Sugar (and other) transporter OATP PF03137.20 AIM22712.1 - 2.3 6.4 21.1 0.057 11.7 4.5 3.4 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Amidase_3 PF01520.18 AIM22713.1 - 1.3e-48 165.4 0.0 1.8e-48 164.9 0.0 1.2 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase Porin_1 PF00267.21 AIM22714.1 - 5.6e-47 160.8 2.5 6.6e-47 160.6 2.5 1.0 1 0 0 1 1 1 1 Gram-negative porin Porin_4 PF13609.6 AIM22714.1 - 3.4e-12 46.7 7.7 5.9e-12 46.0 7.7 1.4 1 1 0 1 1 1 1 Gram-negative porin OMP_b-brl PF13505.6 AIM22714.1 - 0.00014 22.0 3.9 0.0035 17.5 0.9 3.1 2 1 1 3 3 3 1 Outer membrane protein beta-barrel domain Phenol_MetA_deg PF13557.6 AIM22714.1 - 0.029 14.3 8.0 0.21 11.5 0.4 2.8 3 0 0 3 3 3 0 Putative MetA-pathway of phenol degradation Epimerase PF01370.21 AIM22715.1 - 5.5e-05 22.7 0.0 7e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AIM22715.1 - 0.064 12.6 0.0 0.074 12.4 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Abhydrolase_1 PF00561.20 AIM22716.1 - 8.5e-24 84.6 2.0 2.3e-23 83.2 2.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AIM22716.1 - 1e-22 80.6 2.4 1.7e-13 50.4 1.4 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AIM22716.1 - 1.6e-17 64.8 5.8 1.9e-17 64.6 5.8 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 AIM22716.1 - 1.4e-10 41.0 1.6 5.6e-07 29.2 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family FSH1 PF03959.13 AIM22716.1 - 4.9e-06 26.4 0.4 3.4e-05 23.6 0.4 2.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.7 AIM22716.1 - 1.6e-05 24.7 0.4 0.0063 16.3 0.0 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 AIM22716.1 - 5.2e-05 23.0 0.7 0.0079 15.8 0.1 2.1 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.16 AIM22716.1 - 6.3e-05 22.9 0.0 0.00016 21.5 0.0 1.6 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.10 AIM22716.1 - 0.0012 18.9 0.3 0.0073 16.4 0.0 2.2 3 0 0 3 3 2 1 TAP-like protein DUF915 PF06028.11 AIM22716.1 - 0.002 17.5 0.1 0.023 14.0 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) DLH PF01738.18 AIM22716.1 - 0.003 17.2 0.1 0.0068 16.0 0.0 1.6 2 0 0 2 2 2 1 Dienelactone hydrolase family Ndr PF03096.14 AIM22716.1 - 0.0069 15.1 0.0 0.015 14.0 0.0 1.5 2 0 0 2 2 2 1 Ndr family Ser_hydrolase PF06821.13 AIM22716.1 - 0.018 14.9 0.0 0.68 9.8 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase Esterase_phd PF10503.9 AIM22716.1 - 0.055 13.0 1.8 0.086 12.3 0.0 2.1 2 1 0 2 2 2 0 Esterase PHB depolymerase DUF1749 PF08538.10 AIM22716.1 - 0.11 11.5 0.3 0.27 10.3 0.1 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1749) AXE1 PF05448.12 AIM22716.1 - 0.17 10.5 0.3 0.59 8.8 0.2 1.9 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Aldedh PF00171.22 AIM22717.1 - 2.3e-87 293.5 0.0 2.7e-87 293.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 AIM22717.1 - 0.04 13.0 0.0 0.091 11.8 0.0 1.4 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) peroxidase PF00141.23 AIM22718.1 - 3.7e-87 291.8 0.0 2.3e-46 158.4 0.0 2.2 2 0 0 2 2 2 2 Peroxidase DUF805 PF05656.14 AIM22720.1 - 3e-11 43.6 0.5 3.4e-11 43.5 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF805) DAP10 PF07213.11 AIM22720.1 - 0.017 15.0 0.7 0.022 14.7 0.1 1.5 2 0 0 2 2 2 0 DAP10 membrane protein Glyoxalase_4 PF13669.6 AIM22721.1 - 2e-05 24.8 0.0 0.22 11.8 0.0 2.7 2 1 1 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 AIM22721.1 - 0.00055 20.7 0.7 0.26 12.1 0.1 2.4 2 0 0 2 2 2 2 Glyoxalase-like domain Adhesin_P1_N PF18652.1 AIM22721.1 - 0.12 12.4 0.9 0.4 10.7 0.2 2.0 2 0 0 2 2 2 0 Adhesin P1 N-terminal domain Alginate_exp PF13372.6 AIM22722.1 - 5e-68 229.7 9.0 6e-68 229.4 9.0 1.0 1 0 0 1 1 1 1 Alginate export Peptidase_M10_C PF08548.11 AIM22723.1 - 4.2e-71 238.8 10.9 4.2e-71 238.8 10.9 2.8 2 2 0 2 2 2 1 Peptidase M10 serralysin C terminal Peptidase_M10 PF00413.24 AIM22723.1 - 6.1e-12 45.7 1.8 1.2e-10 41.4 0.8 2.9 2 1 0 2 2 2 1 Matrixin HemolysinCabind PF00353.19 AIM22723.1 - 6.4e-10 38.8 8.3 6.4e-10 38.8 8.3 3.9 3 1 2 5 5 5 3 RTX calcium-binding nonapeptide repeat (4 copies) Reprolysin_4 PF13583.6 AIM22723.1 - 7.4e-06 25.7 5.8 1.1e-05 25.2 4.3 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 AIM22723.1 - 8.6e-06 25.2 0.2 1.6e-05 24.3 0.2 1.4 1 0 0 1 1 1 1 Met-zincin Reprolysin_3 PF13582.6 AIM22723.1 - 1.5e-05 25.5 0.6 4.9e-05 23.9 0.2 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 AIM22723.1 - 8.7e-05 22.7 6.7 0.00018 21.7 6.7 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M66 PF10462.9 AIM22723.1 - 0.00046 19.2 3.5 0.00046 19.2 3.5 1.8 2 0 0 2 2 2 1 Peptidase M66 Reprolysin_2 PF13574.6 AIM22723.1 - 0.0016 18.3 0.6 0.0027 17.6 0.6 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M43 PF05572.13 AIM22723.1 - 0.003 17.5 0.5 0.003 17.5 0.5 1.9 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Peptidase_M57 PF12388.8 AIM22723.1 - 0.0031 17.2 1.2 0.007 16.0 1.2 1.6 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase DUF3152 PF11350.8 AIM22723.1 - 0.014 15.1 0.4 0.061 13.0 0.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3152) Astacin PF01400.24 AIM22723.1 - 0.037 13.7 0.5 0.15 11.7 0.4 2.0 1 1 0 1 1 1 0 Astacin (Peptidase family M12A) Peptidase_M54 PF07998.11 AIM22723.1 - 0.24 11.4 0.0 0.42 10.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M54 NMO PF03060.15 AIM22724.1 - 2.7e-82 276.8 2.0 3.1e-82 276.6 2.0 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 AIM22724.1 - 8.4e-07 28.3 2.0 1.7e-05 24.0 3.8 1.9 2 0 0 2 2 2 1 FMN-dependent dehydrogenase IMPDH PF00478.25 AIM22724.1 - 1.4e-06 27.5 0.0 0.0086 15.1 0.0 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 AIM22724.1 - 0.01 15.3 0.2 0.034 13.6 0.2 1.7 2 0 0 2 2 2 0 Histidine biosynthesis protein Glu_synthase PF01645.17 AIM22724.1 - 0.017 14.3 3.2 0.028 13.6 3.2 1.3 1 0 0 1 1 1 0 Conserved region in glutamate synthase TMP-TENI PF02581.17 AIM22724.1 - 0.053 12.8 0.3 0.14 11.5 0.3 1.7 1 0 0 1 1 1 0 Thiamine monophosphate synthase HEXIM PF15313.6 AIM22724.1 - 0.19 11.9 0.1 0.29 11.3 0.1 1.2 1 0 0 1 1 1 0 Hexamethylene bis-acetamide-inducible protein DHO_dh PF01180.21 AIM22724.1 - 0.22 10.7 0.8 0.36 10.0 0.8 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase MFS_3 PF05977.13 AIM22725.1 - 4.8e-209 695.1 22.4 5.9e-209 694.8 22.4 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1 PF07690.16 AIM22725.1 - 5.3e-32 111.1 50.6 1.6e-28 99.7 40.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 AIM22725.1 - 1.3e-09 37.2 25.2 0.00022 19.9 8.1 3.0 2 1 1 3 3 3 3 MFS/sugar transport protein DoxX PF07681.12 AIM22726.1 - 3.1e-12 46.9 12.4 3.1e-12 46.9 12.4 1.7 2 0 0 2 2 2 1 DoxX SURF4 PF02077.15 AIM22726.1 - 0.00016 21.4 0.1 0.00021 21.0 0.1 1.1 1 0 0 1 1 1 1 SURF4 family DoxX_2 PF13564.6 AIM22726.1 - 0.021 14.9 11.2 0.021 14.9 11.2 1.9 1 1 0 2 2 2 0 DoxX-like family Na_H_antiport_2 PF13726.6 AIM22726.1 - 0.3 11.2 5.7 0.68 10.1 5.6 1.7 1 1 1 2 2 2 0 Na+-H+ antiporter family Abhydrolase_1 PF00561.20 AIM22727.1 - 5.8e-24 85.1 0.2 9.2e-24 84.5 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AIM22727.1 - 5.8e-24 84.7 0.4 1.3e-23 83.5 0.4 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AIM22727.1 - 4.3e-20 73.3 3.1 5.3e-20 73.0 3.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 AIM22727.1 - 2e-09 37.3 0.1 1.6e-06 27.7 0.0 2.4 2 1 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 AIM22727.1 - 0.0018 18.1 0.0 0.39 10.5 0.0 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 AIM22727.1 - 0.0034 17.3 0.0 0.021 14.7 0.0 2.0 2 0 0 2 2 2 1 Serine hydrolase DLH PF01738.18 AIM22727.1 - 0.017 14.7 0.0 0.03 13.9 0.0 1.5 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_4 PF08386.10 AIM22727.1 - 0.042 14.0 0.1 0.19 11.9 0.0 2.0 2 0 0 2 2 2 0 TAP-like protein Abhydrolase_2 PF02230.16 AIM22727.1 - 0.056 13.2 0.0 0.14 11.9 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF1749 PF08538.10 AIM22727.1 - 0.059 12.4 0.0 0.13 11.4 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) 3HBOH PF10605.9 AIM22727.1 - 0.11 10.7 0.0 0.17 10.1 0.0 1.2 1 0 0 1 1 1 0 3HB-oligomer hydrolase (3HBOH) DUF915 PF06028.11 AIM22727.1 - 0.13 11.6 0.0 0.29 10.4 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) MFS_1 PF07690.16 AIM22728.1 - 1.5e-31 109.7 54.3 1.5e-31 109.7 54.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 AIM22728.1 - 0.023 14.0 38.6 0.029 13.7 38.6 1.1 1 0 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB Asp_Arg_Hydrox PF05118.15 AIM22729.1 - 1.9e-40 138.2 0.0 2.4e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Cupin_2 PF07883.11 AIM22729.1 - 0.00018 21.1 0.1 0.0013 18.4 0.0 2.0 2 0 0 2 2 2 1 Cupin domain PI_PP_I PF18363.1 AIM22729.1 - 0.055 13.6 0.0 0.089 13.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoinositide phosphatase insertion domain NmrA PF05368.13 AIM22730.1 - 2.8e-20 72.9 0.0 3.7e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 AIM22730.1 - 0.00011 22.5 0.0 0.0003 21.1 0.0 1.8 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain HxlR PF01638.17 AIM22731.1 - 5.6e-19 67.8 0.1 7.7e-19 67.3 0.1 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix MarR PF01047.22 AIM22731.1 - 6.2e-07 29.3 0.0 1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 MarR family PadR PF03551.14 AIM22731.1 - 0.00011 22.1 0.1 0.00016 21.5 0.1 1.5 1 1 0 1 1 1 1 Transcriptional regulator PadR-like family MarR_2 PF12802.7 AIM22731.1 - 0.00027 20.8 0.1 0.00045 20.0 0.1 1.3 1 0 0 1 1 1 1 MarR family HTH_Crp_2 PF13545.6 AIM22731.1 - 0.00036 20.5 0.1 0.00056 19.8 0.1 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain MerR PF00376.23 AIM22731.1 - 0.0021 17.8 0.3 0.04 13.7 0.3 2.4 1 1 0 1 1 1 1 MerR family regulatory protein HTH_34 PF13601.6 AIM22731.1 - 0.0028 17.8 0.0 0.0041 17.3 0.0 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_12 PF08461.10 AIM22731.1 - 0.0081 16.1 0.4 0.018 15.0 0.4 1.6 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain Replic_Relax PF13814.6 AIM22731.1 - 0.011 15.8 0.1 0.013 15.6 0.1 1.1 1 0 0 1 1 1 0 Replication-relaxation HTH_20 PF12840.7 AIM22731.1 - 0.024 14.7 0.8 0.043 13.9 0.8 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_45 PF14947.6 AIM22731.1 - 0.15 12.0 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix ABC_tran PF00005.27 AIM22732.1 - 2.1e-30 106.0 0.0 2.8e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIM22732.1 - 6.6e-12 45.8 3.4 7.6e-07 29.2 0.1 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system BCA_ABC_TP_C PF12399.8 AIM22732.1 - 6e-05 22.9 0.0 0.0001 22.1 0.0 1.3 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_16 PF13191.6 AIM22732.1 - 0.00014 22.3 0.1 0.00022 21.7 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AIM22732.1 - 0.00032 20.4 0.0 0.0011 18.7 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 AIM22732.1 - 0.00047 19.7 0.1 0.11 11.9 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 AIM22732.1 - 0.0045 16.9 0.0 0.0072 16.2 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 AIM22732.1 - 0.011 15.8 0.0 0.022 14.9 0.0 1.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_15 PF13175.6 AIM22732.1 - 0.011 15.4 0.0 0.023 14.4 0.0 1.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 AIM22732.1 - 0.012 15.1 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.7 AIM22732.1 - 0.015 14.3 0.0 0.023 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_23 PF13476.6 AIM22732.1 - 0.027 15.0 0.0 0.044 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 AIM22732.1 - 0.071 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.17 AIM22732.1 - 0.082 12.6 0.0 0.32 10.7 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein NB-ARC PF00931.22 AIM22732.1 - 0.17 11.0 0.1 0.46 9.6 0.1 1.7 1 1 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.6 AIM22732.1 - 0.18 12.0 0.0 0.36 11.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 AIM22732.1 - 0.18 11.8 0.0 0.38 10.8 0.0 1.8 1 1 0 1 1 1 0 Dynamin family ABC_tran PF00005.27 AIM22733.1 - 1.5e-27 96.8 0.0 5.9e-27 94.9 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIM22733.1 - 1.7e-10 41.2 0.1 7e-05 22.8 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system BCA_ABC_TP_C PF12399.8 AIM22733.1 - 2e-10 40.4 0.2 3.3e-10 39.6 0.2 1.4 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_23 PF13476.6 AIM22733.1 - 7.5e-06 26.6 0.5 1.2e-05 26.0 0.5 1.2 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 AIM22733.1 - 0.00053 19.5 0.1 0.033 13.6 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AIM22733.1 - 0.0019 17.9 0.1 0.0042 16.8 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 AIM22733.1 - 0.0027 17.3 0.1 0.47 10.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AIM22733.1 - 0.0034 17.8 0.0 0.058 13.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_15 PF13175.6 AIM22733.1 - 0.0044 16.8 0.0 0.0072 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AIM22733.1 - 0.0058 16.9 0.2 0.048 13.9 0.1 2.1 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.9 AIM22733.1 - 0.0062 15.4 0.3 0.17 10.6 0.0 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_30 PF13604.6 AIM22733.1 - 0.007 16.1 0.1 0.025 14.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 AIM22733.1 - 0.017 15.0 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase FeoB_N PF02421.18 AIM22733.1 - 0.044 13.3 0.1 0.1 12.2 0.1 1.6 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_27 PF13514.6 AIM22733.1 - 0.049 13.2 0.0 0.091 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 AIM22733.1 - 0.07 12.7 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 AIM22733.1 - 0.08 13.0 0.0 0.14 12.2 0.1 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase BPD_transp_2 PF02653.16 AIM22734.1 - 1.6e-48 165.2 34.7 1.6e-48 165.2 34.7 2.1 1 1 1 2 2 2 1 Branched-chain amino acid transport system / permease component DUF3382 PF11862.8 AIM22734.1 - 2.8e-18 66.0 1.9 2.8e-18 66.0 1.9 4.1 5 0 0 5 5 5 1 Domain of unknown function (DUF3382) YqjK PF13997.6 AIM22734.1 - 7.5 6.9 8.5 1.7 9.0 0.7 3.0 3 0 0 3 3 3 0 YqjK-like protein BPD_transp_2 PF02653.16 AIM22735.1 - 2.9e-52 177.5 37.3 3.3e-52 177.3 37.3 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component Monooxygenase_B PF04744.12 AIM22735.1 - 0.51 9.1 2.0 0.46 9.3 0.3 1.6 2 0 0 2 2 2 0 Monooxygenase subunit B protein E1-E2_ATPase PF00122.20 AIM22735.1 - 1.2 8.7 6.3 0.071 12.6 0.4 2.0 2 0 0 2 2 2 0 E1-E2 ATPase Peripla_BP_6 PF13458.6 AIM22736.1 - 9.3e-64 216.2 9.5 1.1e-63 216.0 9.5 1.0 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 AIM22736.1 - 1.5e-25 90.1 0.0 3e-25 89.1 0.0 1.4 1 1 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_5 PF13433.6 AIM22736.1 - 1.5e-21 76.8 0.3 2.4e-21 76.2 0.3 1.3 1 1 0 1 1 1 1 Periplasmic binding protein domain Toprim_2 PF13155.6 AIM22736.1 - 0.007 16.8 0.3 0.022 15.2 0.1 1.9 2 0 0 2 2 2 1 Toprim-like PhnG PF06754.12 AIM22736.1 - 0.01 15.8 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 Phosphonate metabolism protein PhnG Toprim_3 PF13362.6 AIM22736.1 - 0.018 15.4 0.3 0.079 13.3 0.1 2.1 2 0 0 2 2 2 0 Toprim domain Nitro_FeMo-Co PF02579.17 AIM22736.1 - 0.17 12.2 0.6 3 8.2 0.0 2.8 3 1 1 4 4 4 0 Dinitrogenase iron-molybdenum cofactor HTH_37 PF13744.6 AIM22737.1 - 1.2e-09 38.0 1.2 1.4e-09 37.8 1.2 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 AIM22737.1 - 0.00021 21.3 0.4 0.00032 20.7 0.4 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 AIM22737.1 - 0.0011 19.3 0.6 0.0017 18.7 0.1 1.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 AIM22737.1 - 0.0075 16.3 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain Gp49 PF05973.14 AIM22738.1 - 2.2e-22 79.0 0.0 4.2e-22 78.1 0.0 1.4 2 0 0 2 2 2 1 Phage derived protein Gp49-like (DUF891) MFS_1 PF07690.16 AIM22739.1 - 4.3e-35 121.3 74.8 4.1e-28 98.3 45.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AIM22739.1 - 1.5e-33 116.4 32.1 2.5e-23 82.7 9.9 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 AIM22739.1 - 0.00024 20.1 8.1 0.01 14.7 0.9 2.9 1 1 0 2 2 2 2 MFS_1 like family SBP_bac_11 PF13531.6 AIM22740.1 - 1.5e-37 129.5 1.1 1.8e-37 129.3 1.1 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AIM22740.1 - 0.00022 21.3 0.2 0.34 10.8 0.0 2.3 1 1 0 2 2 2 2 Bacterial extracellular solute-binding protein HupE_UreJ PF04955.12 AIM22740.1 - 0.023 14.2 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 HupE / UreJ protein LysR_substrate PF03466.20 AIM22741.1 - 3.8e-41 140.8 0.2 5.5e-41 140.2 0.2 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM22741.1 - 4.2e-20 71.5 0.1 8.4e-20 70.5 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AIM22741.1 - 0.0059 16.4 0.2 0.013 15.3 0.2 1.5 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain PBP_like PF12727.7 AIM22741.1 - 0.04 13.0 0.0 2.1 7.4 0.0 2.3 1 1 1 2 2 2 0 PBP superfamily domain HTH_50 PF18024.1 AIM22741.1 - 0.065 12.9 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Sel_put PF04328.13 AIM22741.1 - 0.16 12.0 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Selenoprotein, putative DAGK_prokar PF01219.19 AIM22742.1 - 9.1e-21 73.6 1.8 9.9e-21 73.5 1.8 1.0 1 0 0 1 1 1 1 Prokaryotic diacylglycerol kinase Acetyltransf_1 PF00583.25 AIM22743.1 - 0.021 15.1 0.3 8.1 6.7 0.1 3.2 2 2 0 2 2 2 0 Acetyltransferase (GNAT) family AMP-binding PF00501.28 AIM22744.1 - 9.7e-75 251.7 0.0 1.3e-74 251.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C_2 PF14535.6 AIM22744.1 - 5.5e-07 29.8 0.0 1e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.21 AIM22745.1 - 1.2e-26 93.7 0.0 7.6e-26 91.0 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 AIM22745.1 - 2.3e-19 70.0 0.0 3.3e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 AIM22745.1 - 9.6e-19 67.4 0.0 9.6e-12 44.5 0.0 2.1 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 AIM22745.1 - 5.6e-15 55.2 0.2 3.8e-05 23.0 0.0 3.1 2 1 1 3 3 3 3 Male sterility protein NmrA PF05368.13 AIM22745.1 - 3.9e-14 52.8 0.0 4.7e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 AIM22745.1 - 9.2e-14 51.6 0.0 2.8e-10 40.1 0.0 3.1 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase adh_short PF00106.25 AIM22745.1 - 3.6e-07 29.8 0.4 2.9e-06 26.9 0.4 2.0 1 1 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 AIM22745.1 - 3.1e-06 26.5 0.1 0.00017 20.8 0.1 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 AIM22745.1 - 6.9e-06 25.4 0.0 0.00013 21.2 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 AIM22745.1 - 0.00015 21.7 0.6 0.032 14.1 0.6 2.5 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 AIM22745.1 - 0.00016 21.9 0.0 0.00027 21.2 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain PP-binding PF00550.25 AIM22746.1 - 3.6e-11 43.3 1.2 4e-11 43.1 1.2 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site Aminotran_1_2 PF00155.21 AIM22747.1 - 1.2e-53 182.6 0.0 1.5e-53 182.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 AIM22747.1 - 0.00086 18.4 0.0 0.0018 17.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 AIM22747.1 - 0.0035 15.9 0.0 0.0047 15.5 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.20 AIM22747.1 - 0.0046 15.7 0.0 0.036 12.8 0.0 2.0 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Beta_elim_lyase PF01212.21 AIM22747.1 - 0.02 14.2 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 AIM22747.1 - 0.031 13.6 0.1 0.085 12.1 0.1 1.7 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Thymidylate_kin PF02223.17 AIM22748.1 - 0.00062 19.5 0.1 0.037 13.7 0.1 2.5 1 1 0 1 1 1 1 Thymidylate kinase Zeta_toxin PF06414.12 AIM22748.1 - 0.013 14.7 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ATP_bind_1 PF03029.17 AIM22748.1 - 0.015 15.1 0.1 0.024 14.4 0.1 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 AIM22748.1 - 0.015 15.8 0.1 0.023 15.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 AIM22748.1 - 0.017 15.5 0.0 0.032 14.6 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 AIM22748.1 - 0.023 15.2 0.0 0.037 14.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 AIM22748.1 - 0.03 14.5 0.1 0.09 12.9 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AIM22748.1 - 0.051 13.8 0.0 0.093 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 AIM22748.1 - 0.1 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_17 PF13207.6 AIM22748.1 - 0.11 13.0 0.2 0.42 11.0 0.1 2.0 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 AIM22748.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Dynamin family AAA_19 PF13245.6 AIM22748.1 - 0.15 12.4 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 AIM22749.1 - 7.9e-05 22.4 0.0 0.00061 19.5 0.0 2.2 3 0 0 3 3 3 1 Thymidylate kinase AAA_22 PF13401.6 AIM22749.1 - 0.00051 20.3 0.0 0.00089 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 AIM22749.1 - 0.0012 18.7 0.0 0.0034 17.3 0.0 1.7 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.6 AIM22749.1 - 0.0013 19.3 0.4 0.0031 18.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 AIM22749.1 - 0.012 16.1 0.0 0.014 15.9 0.0 1.6 1 1 0 1 1 1 0 ABC transporter DUF463 PF04317.12 AIM22749.1 - 0.013 14.5 0.0 0.045 12.7 0.1 1.7 1 1 1 2 2 2 0 YcjX-like family, DUF463 AAA_33 PF13671.6 AIM22749.1 - 0.013 15.7 0.0 0.02 15.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 AIM22749.1 - 0.013 15.8 0.0 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AIM22749.1 - 0.014 15.1 0.0 0.063 13.0 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain APS_kinase PF01583.20 AIM22749.1 - 0.017 15.0 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase PRK PF00485.18 AIM22749.1 - 0.06 13.1 0.1 0.092 12.5 0.1 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family DUF87 PF01935.17 AIM22749.1 - 0.066 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain NTPase_1 PF03266.15 AIM22749.1 - 0.076 12.9 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 NTPase KTI12 PF08433.10 AIM22749.1 - 0.11 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_14 PF13173.6 AIM22749.1 - 0.12 12.4 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 AIM22749.1 - 0.13 12.6 0.1 0.14 12.6 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 AIM22749.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 AIM22749.1 - 0.17 11.8 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MeaB PF03308.16 AIM22749.1 - 0.19 10.7 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 AIM22749.1 - 0.22 11.2 0.0 0.32 10.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 AIM22749.1 - 0.23 11.9 0.0 0.44 11.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.22 AIM22749.1 - 0.23 10.6 0.0 0.32 10.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Thymidylate_kin PF02223.17 AIM22750.1 - 2.2e-06 27.5 0.4 0.0087 15.7 0.1 2.7 2 1 0 2 2 2 2 Thymidylate kinase AAA_18 PF13238.6 AIM22750.1 - 0.0023 18.5 0.0 0.0064 17.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AIM22750.1 - 0.0039 17.4 0.0 0.0088 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 AIM22750.1 - 0.0043 17.3 0.3 0.049 13.9 0.3 2.5 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 AIM22750.1 - 0.0079 16.6 0.2 0.014 15.8 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain Ploopntkinase3 PF18751.1 AIM22750.1 - 0.014 15.3 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_33 PF13671.6 AIM22750.1 - 0.016 15.3 1.4 0.019 15.1 0.1 1.9 2 2 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 AIM22750.1 - 0.017 15.5 0.0 0.034 14.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 AIM22750.1 - 0.019 14.5 0.3 0.14 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 AIM22750.1 - 0.02 14.8 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 AIM22750.1 - 0.077 12.2 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain RsgA_GTPase PF03193.16 AIM22750.1 - 0.1 12.5 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase ABC_tran PF00005.27 AIM22750.1 - 0.11 13.0 0.1 0.21 12.1 0.1 1.4 1 0 0 1 1 1 0 ABC transporter HrpA_pilin PF09589.10 AIM22750.1 - 0.15 12.7 0.0 0.3 11.8 0.0 1.4 1 0 0 1 1 1 0 HrpA pilus formation protein AAA_7 PF12775.7 AIM22750.1 - 0.19 11.2 0.0 0.35 10.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Polysacc_synt_3 PF13440.6 AIM22751.1 - 1.1e-08 34.7 5.6 1.1e-08 34.7 5.6 2.2 1 1 1 2 2 2 2 Polysaccharide biosynthesis protein Polysacc_synt PF01943.17 AIM22751.1 - 1.4e-05 24.6 26.2 0.00037 20.0 9.3 2.3 1 1 1 2 2 2 2 Polysaccharide biosynthesis protein Polysacc_synt_C PF14667.6 AIM22751.1 - 0.00012 22.2 25.7 0.00071 19.7 9.4 3.9 4 1 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain YtfJ_HI0045 PF09695.10 AIM22753.1 - 5.5e-62 208.1 0.0 6.2e-62 207.9 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (YtfJ_HI0045) LptF_LptG PF03739.14 AIM22754.1 - 1.1e-52 179.0 2.9 1.3e-52 178.8 2.9 1.0 1 0 0 1 1 1 1 Lipopolysaccharide export system permease LptF/LptG PIG-Y PF15159.6 AIM22754.1 - 1.4 9.8 6.0 25 5.9 1.9 3.1 2 1 1 3 3 3 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y LptF_LptG PF03739.14 AIM22755.1 - 2.5e-55 187.8 8.3 2.8e-55 187.6 8.3 1.0 1 0 0 1 1 1 1 Lipopolysaccharide export system permease LptF/LptG DUF5471 PF17565.2 AIM22755.1 - 0.14 12.5 1.2 1.4 9.2 0.0 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5471) HMG-CoA_red PF00368.18 AIM22755.1 - 0.21 10.6 0.3 0.3 10.0 0.3 1.1 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A reductase Lipase_3 PF01764.25 AIM22756.1 - 0.049 13.5 0.1 0.097 12.5 0.1 1.4 1 0 0 1 1 1 0 Lipase (class 3) Ank PF00023.30 AIM22757.1 - 0.00011 22.4 0.1 5.7 7.6 0.0 4.5 5 0 0 5 5 5 1 Ankyrin repeat Ank_2 PF12796.7 AIM22757.1 - 0.00028 21.4 0.0 0.00093 19.7 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 AIM22757.1 - 0.0007 20.1 0.1 0.083 13.5 0.0 2.9 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 AIM22757.1 - 0.0019 18.4 0.0 0.18 12.1 0.2 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) DUF4919 PF16266.5 AIM22757.1 - 0.033 14.1 0.1 0.051 13.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4919) Ank_3 PF13606.6 AIM22757.1 - 0.055 14.0 0.1 25 5.9 0.0 3.7 4 1 0 4 4 4 0 Ankyrin repeat MaoC_dehydrat_N PF13452.6 AIM22757.1 - 0.14 12.3 0.0 2.3 8.4 0.0 2.2 1 1 0 1 1 1 0 N-terminal half of MaoC dehydratase Ank_4 PF13637.6 AIM22758.1 - 6.8e-05 23.3 0.0 0.00034 21.1 0.0 2.3 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 AIM22758.1 - 0.00082 19.6 0.1 0.032 14.6 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 AIM22758.1 - 0.0012 19.1 0.0 1.4 9.8 0.0 3.7 4 1 0 4 4 4 1 Ankyrin repeat Ank_2 PF12796.7 AIM22758.1 - 0.0023 18.5 0.0 0.0061 17.1 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Beta-lactamase PF00144.24 AIM22759.1 - 1.4e-41 142.9 2.6 1.9e-41 142.4 2.6 1.1 1 0 0 1 1 1 1 Beta-lactamase HTH_1 PF00126.27 AIM22760.1 - 6.1e-14 51.7 1.2 1.7e-13 50.3 0.2 2.4 3 0 0 3 3 3 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 AIM22760.1 - 5.2e-13 48.8 0.5 1.2e-12 47.7 0.5 1.5 1 0 0 1 1 1 1 LysR substrate binding domain Peripla_BP_1 PF00532.21 AIM22761.1 - 4.9e-20 72.1 0.0 6.6e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_4 PF13407.6 AIM22761.1 - 4.6e-18 65.7 0.0 1e-17 64.6 0.0 1.6 1 1 1 2 2 2 1 Periplasmic binding protein domain LacI PF00356.21 AIM22761.1 - 5.7e-17 61.2 0.4 4.9e-16 58.2 0.1 2.2 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family Peripla_BP_3 PF13377.6 AIM22761.1 - 5.2e-07 30.1 0.0 1e-06 29.2 0.0 1.5 1 0 0 1 1 1 1 Periplasmic binding protein-like domain Aldolase_II PF00596.21 AIM22762.1 - 4.4e-46 157.2 0.1 5.5e-46 156.8 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain AP_endonuc_2 PF01261.24 AIM22763.1 - 2.4e-33 115.3 0.1 3.4e-33 114.9 0.1 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Methyltrans_RNA PF04452.14 AIM22763.1 - 0.13 11.6 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 RNA methyltransferase FGGY_N PF00370.21 AIM22764.1 - 1.8e-59 201.3 0.0 2.3e-59 200.9 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 AIM22764.1 - 3.6e-22 79.1 0.1 8.5e-22 77.9 0.1 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 AIM22764.1 - 0.0018 17.8 0.3 0.0032 17.0 0.3 1.4 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family BPD_transp_2 PF02653.16 AIM22765.1 - 2.5e-52 177.7 40.1 3.4e-52 177.2 40.1 1.2 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component DUF3493 PF11998.8 AIM22765.1 - 3.2 8.0 6.3 0.96 9.7 0.8 2.9 2 1 0 2 2 2 0 Low psii accumulation1 / Rep27 ABC_tran PF00005.27 AIM22766.1 - 1.3e-47 161.8 0.0 9e-29 100.7 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 AIM22766.1 - 4.7e-09 36.5 0.4 0.04 13.7 0.0 3.1 2 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AIM22766.1 - 0.0015 18.2 0.2 0.0052 16.5 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_10 PF12846.7 AIM22766.1 - 0.0097 14.9 0.0 0.73 8.7 0.0 2.2 1 1 0 2 2 2 1 AAA-like domain RsgA_GTPase PF03193.16 AIM22766.1 - 0.01 15.7 0.0 0.099 12.5 0.0 2.5 3 0 0 3 3 3 0 RsgA GTPase AFG1_ATPase PF03969.16 AIM22766.1 - 0.015 14.2 0.1 0.23 10.3 0.0 2.1 2 0 0 2 2 2 0 AFG1-like ATPase AAA_25 PF13481.6 AIM22766.1 - 0.019 14.6 0.4 0.96 9.0 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 AIM22766.1 - 0.036 14.4 0.4 0.1 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain TniB PF05621.11 AIM22766.1 - 0.043 13.2 0.2 1.5 8.2 0.0 2.6 3 0 0 3 3 3 0 Bacterial TniB protein AAA_23 PF13476.6 AIM22766.1 - 0.064 13.7 0.2 0.15 12.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 AIM22766.1 - 0.084 12.6 0.4 3.6 7.3 0.0 2.9 2 1 0 2 2 2 0 AAA domain SMC_N PF02463.19 AIM22766.1 - 0.094 12.1 0.0 0.94 8.9 0.0 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 AIM22766.1 - 0.13 11.1 3.6 14 4.3 0.0 3.5 4 1 0 4 4 4 0 Predicted ATPase of the ABC class TsaE PF02367.17 AIM22766.1 - 0.18 11.8 0.1 2.7 8.0 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF374 PF04028.13 AIM22766.1 - 0.23 11.0 1.1 1.4 8.5 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF374) AAA_22 PF13401.6 AIM22766.1 - 0.45 10.8 2.8 16 5.8 0.0 3.3 3 1 0 3 3 3 0 AAA domain Peripla_BP_4 PF13407.6 AIM22767.1 - 5.9e-53 180.1 8.4 7.7e-53 179.7 8.4 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 AIM22767.1 - 6.1e-15 55.4 0.7 7.7e-15 55.1 0.7 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_3 PF13377.6 AIM22767.1 - 1e-05 26.0 0.1 0.00029 21.2 0.0 2.1 2 0 0 2 2 2 1 Periplasmic binding protein-like domain SBP_bac_11 PF13531.6 AIM22767.1 - 0.0068 16.2 0.2 0.012 15.4 0.2 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein ADH_zinc_N PF00107.26 AIM22768.1 - 9.5e-24 83.8 0.0 1.4e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AIM22768.1 - 1.9e-20 72.8 0.1 3.9e-20 71.7 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 AIM22768.1 - 8.7e-06 25.4 0.5 0.00014 21.4 0.5 2.1 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 AIM22768.1 - 0.013 16.5 0.0 0.032 15.3 0.0 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase DUF496 PF04363.12 AIM22769.1 - 5.4e-47 157.8 10.1 6.1e-47 157.6 10.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF496) YvfG PF09628.10 AIM22769.1 - 0.014 15.7 0.1 0.023 15.1 0.1 1.3 1 0 0 1 1 1 0 YvfG protein FUSC_2 PF13515.6 AIM22770.1 - 3.1e-14 53.2 16.6 5.1e-14 52.5 16.6 1.4 1 0 0 1 1 1 1 Fusaric acid resistance protein-like FUSC PF04632.12 AIM22770.1 - 2.7e-13 49.4 20.2 6.2e-13 48.2 20.2 1.5 1 1 0 1 1 1 1 Fusaric acid resistance protein family ALMT PF11744.8 AIM22770.1 - 0.0072 15.2 4.0 0.011 14.6 4.0 1.2 1 0 0 1 1 1 1 Aluminium activated malate transporter GtrA PF04138.14 AIM22770.1 - 0.32 11.2 4.2 0.53 10.5 0.2 2.5 2 0 0 2 2 2 0 GtrA-like protein Amidase_2 PF01510.25 AIM22771.1 - 8.5e-27 94.1 0.0 1.7e-26 93.2 0.0 1.5 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase PG_binding_1 PF01471.18 AIM22771.1 - 0.0099 16.1 0.7 0.034 14.4 0.4 2.0 2 0 0 2 2 2 1 Putative peptidoglycan binding domain Phage_int_SAM_1 PF02899.17 AIM22771.1 - 0.013 15.8 0.1 0.033 14.5 0.1 1.8 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Peptidase_S24 PF00717.23 AIM22772.1 - 2.7e-10 40.1 0.1 5.3e-10 39.1 0.1 1.5 1 0 0 1 1 1 1 Peptidase S24-like NAD_binding_4 PF07993.12 AIM22773.1 - 5.4e-35 120.8 0.0 7e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 AIM22773.1 - 3.9e-11 42.9 0.0 5.3e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 AIM22773.1 - 4.3e-06 25.9 0.0 7.3e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 AIM22773.1 - 8.7e-05 22.1 0.0 0.00024 20.6 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 AIM22773.1 - 0.0016 18.4 0.0 0.024 14.5 0.0 2.2 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 AIM22773.1 - 0.0031 16.7 0.0 0.0046 16.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DNA_pol3_theta PF06440.11 AIM22774.1 - 9e-14 50.9 0.1 1e-13 50.7 0.1 1.0 1 0 0 1 1 1 1 DNA polymerase III, theta subunit Exonuc_X-T_C PF08411.10 AIM22775.1 - 8.1e-109 362.9 0.2 1e-108 362.6 0.2 1.1 1 0 0 1 1 1 1 Exonuclease C-terminal RNase_T PF00929.24 AIM22775.1 - 1.2e-27 97.5 0.0 2.1e-27 96.7 0.0 1.4 1 0 0 1 1 1 1 Exonuclease AA_permease PF00324.21 AIM22776.1 - 1.8e-36 125.8 40.6 2.5e-36 125.3 40.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 AIM22776.1 - 5.8e-36 124.2 40.9 7.9e-36 123.8 40.9 1.1 1 0 0 1 1 1 1 Amino acid permease CrgA PF06781.12 AIM22776.1 - 1.3 9.1 0.0 1.3 9.1 0.0 4.4 4 2 1 5 5 5 0 Cell division protein CrgA Gln-synt_C PF00120.24 AIM22777.1 - 9.8e-104 347.0 0.0 1.2e-103 346.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 AIM22777.1 - 0.02 14.7 0.0 0.045 13.6 0.0 1.7 1 0 0 1 1 1 0 Glutamine synthetase N-terminal domain Cupin_2 PF07883.11 AIM22778.1 - 3.7e-16 58.6 0.1 7.1e-16 57.7 0.0 1.5 2 0 0 2 2 2 1 Cupin domain HTH_3 PF01381.22 AIM22778.1 - 2.3e-14 53.2 0.3 3.4e-14 52.6 0.3 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 AIM22778.1 - 7.6e-11 42.2 0.0 1.3e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 AIM22778.1 - 2.8e-09 36.9 0.0 4.6e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain MqsA_antitoxin PF15731.5 AIM22778.1 - 1e-05 25.6 0.1 2.5e-05 24.4 0.0 1.6 2 0 0 2 2 2 1 Antitoxin component of bacterial toxin-antitoxin system, MqsA HTH_37 PF13744.6 AIM22778.1 - 0.00013 21.8 0.3 0.0014 18.5 0.2 2.3 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_26 PF13443.6 AIM22778.1 - 0.00024 21.5 0.0 0.00064 20.1 0.0 1.7 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_25 PF13413.6 AIM22778.1 - 0.0036 17.1 0.1 0.0058 16.5 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain AraC_binding PF02311.19 AIM22778.1 - 0.007 16.3 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain Death PF00531.22 AIM22778.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Death domain CENP-C_C PF11699.8 AIM22778.1 - 0.15 12.3 0.0 0.23 11.7 0.0 1.2 1 0 0 1 1 1 0 Mif2/CENP-C like ABC_tran PF00005.27 AIM22779.1 - 5.3e-45 153.3 0.0 4.3e-25 88.8 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 AIM22779.1 - 3.4e-11 43.5 0.5 0.00051 20.0 0.0 3.6 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIM22779.1 - 7.8e-07 28.7 0.0 0.23 10.9 0.0 3.2 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AIM22779.1 - 9e-07 28.6 0.2 0.00032 20.4 0.1 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AIM22779.1 - 5.2e-06 26.5 0.0 0.0083 16.1 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 AIM22779.1 - 1.9e-05 24.9 4.6 0.024 14.9 0.6 3.6 2 2 0 2 2 2 2 AAA domain AAA_30 PF13604.6 AIM22779.1 - 4.1e-05 23.4 0.9 0.033 13.9 0.1 3.2 3 1 0 3 3 3 1 AAA domain AAA_23 PF13476.6 AIM22779.1 - 9.6e-05 23.0 0.1 0.00079 20.0 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AIM22779.1 - 0.00013 22.4 0.1 0.27 11.6 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 AIM22779.1 - 0.00019 22.0 0.6 0.22 12.1 0.1 3.1 2 2 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 AIM22779.1 - 0.00038 20.5 0.1 1.1 9.4 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.6 AIM22779.1 - 0.002 17.7 0.7 1.1 8.8 0.0 3.4 4 0 0 4 4 4 1 AAA domain SbcCD_C PF13558.6 AIM22779.1 - 0.0051 17.0 0.6 0.68 10.2 0.0 3.4 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 AIM22779.1 - 0.0054 16.9 1.5 0.68 10.1 0.1 3.2 2 2 0 2 2 2 1 AAA domain AAA_28 PF13521.6 AIM22779.1 - 0.0093 16.2 0.3 0.21 11.8 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_27 PF13514.6 AIM22779.1 - 0.018 14.7 1.2 0.055 13.1 0.1 2.3 3 0 0 3 3 3 0 AAA domain Ploopntkinase3 PF18751.1 AIM22779.1 - 0.024 14.5 0.0 0.12 12.2 0.0 2.1 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Zeta_toxin PF06414.12 AIM22779.1 - 0.03 13.6 2.3 0.43 9.8 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin Viral_helicase1 PF01443.18 AIM22779.1 - 0.089 12.5 0.0 1.4 8.6 0.0 2.8 4 0 0 4 4 4 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 AIM22779.1 - 0.14 11.3 0.5 16 4.6 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_15 PF13175.6 AIM22779.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain MukB PF04310.12 AIM22779.1 - 0.15 11.8 0.1 0.3 10.9 0.1 1.4 1 0 0 1 1 1 0 MukB N-terminal ABC_ATPase PF09818.9 AIM22779.1 - 0.51 9.1 2.0 0.74 8.5 0.6 1.9 3 0 0 3 3 3 0 Predicted ATPase of the ABC class BPD_transp_2 PF02653.16 AIM22780.1 - 5.3e-39 134.0 41.7 8e-39 133.4 41.7 1.3 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component TonB_dep_Rec PF00593.24 AIM22781.1 - 1.5e-57 196.6 23.7 2.2e-57 196.0 23.7 1.3 1 0 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AIM22781.1 - 1.1e-28 99.9 0.8 3.6e-28 98.3 0.8 1.9 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 AIM22781.1 - 1.1e-13 51.0 4.1 1.1e-13 51.0 4.1 2.5 2 1 0 2 2 2 1 Outer membrane protein beta-barrel family DUF915 PF06028.11 AIM22781.1 - 0.033 13.5 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Peripla_BP_2 PF01497.18 AIM22782.1 - 4.7e-27 95.1 0.1 5.7e-27 94.8 0.1 1.1 1 0 0 1 1 1 1 Periplasmic binding protein MEDS PF14417.6 AIM22782.1 - 0.079 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain FlxA PF14282.6 AIM22782.1 - 0.79 9.7 5.2 1.6 8.8 5.2 1.4 1 0 0 1 1 1 0 FlxA-like protein ABC_tran PF00005.27 AIM22783.1 - 1.6e-26 93.5 0.0 2.2e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIM22783.1 - 2e-14 54.1 0.7 4.4e-06 26.7 0.2 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIM22783.1 - 6.2e-10 38.9 0.4 0.00014 21.4 0.1 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 AIM22783.1 - 3.3e-06 26.8 0.0 8.2e-06 25.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AIM22783.1 - 2.6e-05 23.9 0.0 5.1e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AIM22783.1 - 3.9e-05 24.3 0.0 5.6e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_13 PF13166.6 AIM22783.1 - 0.00013 20.8 0.1 0.12 11.0 0.0 2.1 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 AIM22783.1 - 0.00045 19.1 0.2 0.12 11.2 0.0 2.7 2 1 0 2 2 2 1 Predicted ATPase of the ABC class AAA_16 PF13191.6 AIM22783.1 - 0.0012 19.2 0.1 0.0022 18.4 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AIM22783.1 - 0.0013 19.0 0.0 0.0027 18.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AIM22783.1 - 0.0022 17.9 0.0 0.0039 17.1 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 AIM22783.1 - 0.011 15.5 0.0 0.017 14.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 AIM22783.1 - 0.011 15.5 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 AIM22783.1 - 0.012 15.5 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 AIM22783.1 - 0.013 15.6 0.0 0.025 14.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 AIM22783.1 - 0.045 13.3 0.1 0.093 12.3 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.15 AIM22783.1 - 0.059 13.3 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_28 PF13521.6 AIM22783.1 - 0.079 13.2 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 AIM22783.1 - 0.079 13.0 0.3 0.2 11.7 0.1 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Adeno_IVa2 PF02456.15 AIM22783.1 - 0.1 11.4 0.1 0.16 10.7 0.1 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein IstB_IS21 PF01695.17 AIM22783.1 - 0.1 12.3 0.1 0.81 9.4 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_27 PF13514.6 AIM22783.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 AIM22783.1 - 0.19 11.6 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea SbcCD_C PF13558.6 AIM22783.1 - 0.32 11.3 0.8 3.3 8.0 0.8 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit FecCD PF01032.18 AIM22784.1 - 1.4e-82 277.2 33.2 1.7e-82 277.0 33.2 1.0 1 0 0 1 1 1 1 FecCD transport family ABC-3 PF00950.17 AIM22784.1 - 0.00016 21.3 22.0 0.0002 20.9 22.0 1.2 1 0 0 1 1 1 1 ABC 3 transport family GGDEF PF00990.21 AIM22785.1 - 7.9e-17 61.5 0.0 1.1e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Caps_synth_CapC PF14102.6 AIM22785.1 - 0.45 11.0 6.9 1.4 9.4 6.2 2.1 2 0 0 2 2 2 0 Capsule biosynthesis CapC AA_permease PF00324.21 AIM22786.1 - 1.5e-142 475.6 39.9 1.8e-142 475.3 39.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 AIM22786.1 - 4.3e-41 141.1 43.0 6.4e-41 140.6 43.0 1.3 1 0 0 1 1 1 1 Amino acid permease LysR_substrate PF03466.20 AIM22787.1 - 2e-53 180.8 5.2 3.4e-53 180.1 5.2 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM22787.1 - 2.1e-15 56.4 4.4 2.6e-15 56.1 1.0 2.8 3 0 0 3 3 3 1 Bacterial regulatory helix-turn-helix protein, lysR family PBP_like PF12727.7 AIM22787.1 - 2e-06 27.1 0.0 3e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 PBP superfamily domain AP_endonuc_2 PF01261.24 AIM22789.1 - 1.9e-40 138.6 0.3 2.3e-40 138.3 0.3 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Flagellin_IN PF07196.13 AIM22789.1 - 0.017 15.3 0.1 0.034 14.3 0.1 1.5 1 0 0 1 1 1 0 Flagellin hook IN motif PTS_IIB PF02302.17 AIM22790.1 - 1.4e-19 70.6 3.2 1.7e-18 67.1 0.2 2.5 2 0 0 2 2 2 1 PTS system, Lactose/Cellobiose specific IIB subunit PTS_EIIC PF02378.18 AIM22790.1 - 1.6e-14 53.7 31.1 1.6e-14 53.7 31.1 2.8 2 1 0 2 2 2 1 Phosphotransferase system, EIIC Nitrate_red_gam PF02665.14 AIM22790.1 - 0.34 10.4 3.2 0.74 9.3 0.8 2.4 2 0 0 2 2 2 0 Nitrate reductase gamma subunit DUF745 PF05335.13 AIM22790.1 - 2.2 7.9 15.1 4.6 6.9 15.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF745) PfkB PF00294.24 AIM22791.1 - 5.8e-65 219.6 0.0 7.4e-65 219.2 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 AIM22791.1 - 0.01 15.2 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase PTS_EIIA_2 PF00359.22 AIM22792.1 - 2.1e-32 112.0 0.0 9.2e-30 103.4 0.0 2.4 2 0 0 2 2 2 2 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 PTS-HPr PF00381.19 AIM22792.1 - 2.1e-25 88.7 5.0 8.2e-24 83.7 0.1 3.9 4 0 0 4 4 4 2 PTS HPr component phosphorylation site NUDIX PF00293.28 AIM22793.1 - 1.3e-26 93.1 0.1 1.7e-26 92.8 0.1 1.0 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 AIM22793.1 - 0.0022 18.0 0.1 0.0042 17.1 0.1 1.5 1 1 0 1 1 1 1 NUDIX domain Cytochrom_NNT PF03264.14 AIM22794.1 - 5.7e-70 234.5 3.0 3.3e-68 228.8 1.4 2.1 2 0 0 2 2 2 1 NapC/NirT cytochrome c family, N-terminal region Cytochrome_C7 PF14522.6 AIM22794.1 - 1.4e-09 37.8 8.8 0.00024 21.0 1.1 3.6 3 0 0 3 3 3 2 Cytochrome c7 and related cytochrome c Cytochrom_c3_2 PF14537.6 AIM22794.1 - 9.4e-09 35.6 10.2 0.0015 18.9 1.2 3.3 3 0 0 3 3 3 2 Cytochrome c3 Paired_CXXCH_1 PF09699.10 AIM22794.1 - 1.2e-07 31.3 12.9 0.87 9.4 0.3 5.3 5 0 0 5 5 5 4 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrom_CIII PF02085.16 AIM22794.1 - 0.0038 17.5 19.5 2.2 8.7 4.4 4.2 2 1 2 4 4 4 2 Class III cytochrome C family DUF1924 PF09086.11 AIM22794.1 - 0.026 14.9 14.6 2.8 8.4 0.5 4.4 3 2 1 4 4 4 0 Domain of unknown function (DUF1924) Cytochrom_C552 PF02335.15 AIM22794.1 - 0.063 12.2 7.0 0.7 8.7 0.5 2.8 2 0 0 2 2 2 0 Cytochrome c552 PUA_2 PF14306.6 AIM22794.1 - 0.071 12.8 0.0 0.18 11.5 0.0 1.6 2 0 0 2 2 2 0 PUA-like domain DHC PF09626.10 AIM22794.1 - 0.092 13.6 17.7 3.1 8.7 0.3 5.3 4 1 1 5 5 5 0 Dihaem cytochrome c DUF3365 PF11845.8 AIM22794.1 - 0.11 12.9 9.5 17 5.7 0.0 4.0 2 1 2 4 4 4 0 Protein of unknown function (DUF3365) Cytochrome_C554 PF13435.6 AIM22794.1 - 0.17 12.8 15.7 13 6.7 3.7 4.2 2 1 2 4 4 4 0 Cytochrome c554 and c-prime IRF-2BP1_2 PF11261.8 AIM22794.1 - 0.21 11.2 0.9 6.3 6.4 0.0 3.0 3 0 0 3 3 3 0 Interferon regulatory factor 2-binding protein zinc finger Cytochrome_CBB3 PF13442.6 AIM22794.1 - 0.27 11.6 24.6 1.1 9.6 0.3 5.8 3 3 1 4 4 4 0 Cytochrome C oxidase, cbb3-type, subunit III Cytochrome_P460 PF16694.5 AIM22794.1 - 0.28 11.5 22.1 0.68 10.3 0.1 5.5 4 2 2 6 6 5 0 Cytochrome P460 DUF3795 PF12675.7 AIM22794.1 - 3 8.3 8.9 4 7.9 0.4 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3795) GF_recep_IV PF14843.6 AIM22794.1 - 5.1 6.9 7.7 3.4 7.5 0.2 3.1 3 1 1 4 4 4 0 Growth factor receptor domain IV zf-like PF04071.12 AIM22794.1 - 7.4 6.6 6.9 0.96 9.4 0.8 2.5 2 1 0 2 2 2 0 Cysteine-rich small domain Defensin_5 PF18251.1 AIM22794.1 - 8.1 6.6 18.4 42 4.3 0.2 5.1 5 0 0 5 5 5 0 Fungal defensin Copsin Molybdopterin PF00384.22 AIM22795.1 - 3.7e-94 316.1 0.0 4.5e-94 315.9 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 AIM22795.1 - 5.2e-25 87.6 0.0 2.6e-24 85.4 0.0 2.1 2 0 0 2 2 2 1 Molydopterin dinucleotide binding domain Molybdopterin_N PF18364.1 AIM22795.1 - 3.3e-17 62.2 0.7 1.5e-16 60.1 0.2 2.3 2 0 0 2 2 2 1 Molybdopterin oxidoreductase N-terminal domain TAT_signal PF10518.9 AIM22795.1 - 1.6e-05 24.6 3.0 1.6e-05 24.6 3.0 2.0 2 0 0 2 2 2 1 TAT (twin-arginine translocation) pathway signal sequence FAD-SLDH PF12318.8 AIM22795.1 - 0.044 13.9 0.3 0.089 12.9 0.3 1.5 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase MFS_1 PF07690.16 AIM22796.1 - 1.1e-31 110.1 63.0 4.4e-30 104.8 39.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 AIM22796.1 - 5.2e-07 28.9 19.8 6.8e-06 25.2 17.6 3.1 1 1 1 2 2 2 1 MFS_1 like family MFS_2 PF13347.6 AIM22796.1 - 0.0031 16.1 36.6 0.064 11.8 8.1 3.4 1 1 2 3 3 3 3 MFS/sugar transport protein Phage_holin_7_1 PF16081.5 AIM22796.1 - 0.49 10.6 3.7 2.4 8.3 0.6 3.0 3 1 0 3 3 3 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family DUF5392 PF17370.2 AIM22796.1 - 0.82 9.8 1.8 1.2 9.2 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5392) CxxCxxCC PF03692.15 AIM22797.1 - 4.7e-05 24.0 4.4 0.00014 22.5 4.4 1.8 1 1 0 1 1 1 1 Putative zinc- or iron-chelating domain Trp_Tyr_perm PF03222.13 AIM22798.1 - 1.3e-142 475.5 26.2 1.5e-142 475.3 26.2 1.0 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family AA_permease_2 PF13520.6 AIM22798.1 - 0.022 13.6 41.8 0.19 10.5 41.8 2.0 1 1 0 1 1 1 0 Amino acid permease Elong-fact-P_C PF09285.11 AIM22799.1 - 2.7e-18 65.4 0.0 6e-18 64.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor P, C-terminal EFP_N PF08207.12 AIM22799.1 - 1.1e-16 60.6 0.0 2.2e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain EFP PF01132.20 AIM22799.1 - 2.6e-13 49.8 0.6 4.3e-13 49.1 0.6 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain DUF4357 PF14267.6 AIM22799.1 - 0.062 13.2 0.1 0.22 11.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4357) UxuA PF03786.13 AIM22800.1 - 6.9e-152 505.3 0.0 7.8e-152 505.1 0.0 1.0 1 0 0 1 1 1 1 D-mannonate dehydratase (UxuA) AP_endonuc_2 PF01261.24 AIM22800.1 - 8.6e-09 35.1 0.4 2.6e-08 33.6 0.4 1.7 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel Catalase-rel PF06628.12 AIM22800.1 - 0.0071 16.5 0.0 0.021 15.0 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive Mannitol_dh_C PF08125.13 AIM22801.1 - 1.1e-89 300.2 0.0 1.5e-89 299.7 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 AIM22801.1 - 6.3e-43 146.5 0.0 1.2e-42 145.6 0.0 1.5 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain cobW PF02492.19 AIM22803.1 - 1.4e-39 135.5 0.0 1.9e-39 135.1 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 AIM22803.1 - 1.3e-06 28.2 0.1 3e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain DUF4880 PF16220.5 AIM22803.1 - 0.016 15.1 0.7 0.016 15.1 0.7 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4880) Viral_helicase1 PF01443.18 AIM22803.1 - 0.023 14.4 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 AIM22803.1 - 0.03 14.6 0.0 0.066 13.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AIM22803.1 - 0.051 14.1 0.1 0.38 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF3536 PF12055.8 AIM22803.1 - 0.07 12.4 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3536) TrwB_AAD_bind PF10412.9 AIM22803.1 - 0.12 11.3 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ATP_bind_1 PF03029.17 AIM22803.1 - 0.15 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein T2SSE PF00437.20 AIM22803.1 - 0.19 10.7 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein PAP2 PF01569.21 AIM22804.1 - 7e-08 32.3 10.1 2.2e-07 30.7 7.3 2.3 1 1 1 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 AIM22804.1 - 0.00075 19.2 9.0 0.0014 18.3 9.0 1.5 1 0 0 1 1 1 1 PAP2 superfamily DUF4131 PF13567.6 AIM22804.1 - 0.17 11.5 0.1 0.17 11.5 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) PAP2_C PF14360.6 AIM22804.1 - 0.84 10.2 5.6 0.23 12.0 1.3 2.2 2 1 1 3 3 3 0 PAP2 superfamily C-terminal NLPC_P60 PF00877.19 AIM22805.1 - 2.8e-32 110.9 0.1 4e-32 110.4 0.1 1.2 1 0 0 1 1 1 1 NlpC/P60 family Peptidase_C92 PF05708.12 AIM22805.1 - 0.0018 18.4 0.0 0.94 9.6 0.0 2.1 1 1 1 2 2 2 2 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family LRAT PF04970.13 AIM22805.1 - 0.02 15.2 0.0 0.038 14.3 0.0 1.5 2 0 0 2 2 2 0 Lecithin retinol acyltransferase CHAP PF05257.16 AIM22805.1 - 0.024 15.2 0.0 0.04 14.5 0.0 1.4 1 0 0 1 1 1 0 CHAP domain DUF1287 PF06940.11 AIM22805.1 - 0.056 13.1 0.0 0.48 10.1 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1287) DHQS PF01959.16 AIM22805.1 - 0.067 12.1 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 3-dehydroquinate synthase II DUF5129 PF17173.4 AIM22805.1 - 0.092 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5129) Cupin_3 PF05899.12 AIM22805.1 - 0.14 11.8 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) EAL PF00563.20 AIM22806.1 - 7.3e-66 222.1 0.0 9.7e-66 221.7 0.0 1.2 1 0 0 1 1 1 1 EAL domain CSS-motif PF12792.7 AIM22806.1 - 1.6e-29 102.9 0.1 9.2e-29 100.4 0.1 2.0 2 0 0 2 2 2 1 CSS motif domain associated with EAL SBP_bac_5 PF00496.22 AIM22807.1 - 5.8e-71 239.4 7.8 8.1e-71 239.0 7.8 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle BPD_transp_1 PF00528.22 AIM22808.1 - 3.7e-39 134.4 12.6 3.7e-39 134.4 12.6 2.1 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component E1-E2_ATPase PF00122.20 AIM22808.1 - 9.8 5.7 5.9 16 4.9 1.6 2.4 2 0 0 2 2 2 0 E1-E2 ATPase BPD_transp_1 PF00528.22 AIM22809.1 - 1.7e-26 93.1 14.0 1.7e-26 93.1 14.0 1.6 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 AIM22809.1 - 1.2e-06 28.3 0.8 1.2e-06 28.3 0.8 3.9 4 0 0 4 4 4 1 N-terminal TM domain of oligopeptide transport permease C ABC_tran PF00005.27 AIM22810.1 - 3.2e-60 202.6 0.0 5.6e-30 104.6 0.0 2.2 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 AIM22810.1 - 4.2e-14 52.5 0.0 2.8e-06 26.9 0.0 3.0 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AIM22810.1 - 3.8e-11 43.4 14.0 4.5e-06 26.7 1.1 4.1 2 2 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system oligo_HPY PF08352.12 AIM22810.1 - 5.3e-08 33.3 0.0 0.00043 20.7 0.0 2.7 2 0 0 2 2 2 2 Oligopeptide/dipeptide transporter, C-terminal region AAA_16 PF13191.6 AIM22810.1 - 5.7e-08 33.3 4.9 7.5e-05 23.2 0.6 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 AIM22810.1 - 1e-06 28.4 0.1 0.036 13.8 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 AIM22810.1 - 2e-06 28.1 6.9 0.02 15.2 0.8 3.8 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.6 AIM22810.1 - 5.1e-05 22.9 1.6 0.057 13.0 0.4 3.1 2 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 AIM22810.1 - 7.4e-05 22.5 1.6 2.7 7.7 0.0 4.1 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_5 PF07728.14 AIM22810.1 - 0.00038 20.5 0.3 0.54 10.2 0.0 2.9 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) DUF87 PF01935.17 AIM22810.1 - 0.00039 20.6 1.9 0.57 10.2 0.2 2.7 2 1 0 2 2 2 2 Helicase HerA, central domain AAA_7 PF12775.7 AIM22810.1 - 0.00072 19.1 0.0 1.4 8.4 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region SbcCD_C PF13558.6 AIM22810.1 - 0.0013 18.9 0.1 1.3 9.4 0.0 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.6 AIM22810.1 - 0.0017 17.1 0.0 0.24 10.0 0.1 2.2 2 0 0 2 2 2 1 AAA domain AIG1 PF04548.16 AIM22810.1 - 0.0025 17.2 1.8 0.57 9.5 0.2 2.4 2 0 0 2 2 2 2 AIG1 family RsgA_GTPase PF03193.16 AIM22810.1 - 0.0045 16.9 0.3 1.8 8.4 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase CbiA PF01656.23 AIM22810.1 - 0.016 15.2 4.3 0.7 9.9 0.8 2.8 3 1 0 3 3 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA PF00004.29 AIM22810.1 - 0.018 15.5 1.4 15 6.0 0.0 3.6 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 AIM22810.1 - 0.022 14.5 0.1 7.1 6.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 AIM22810.1 - 0.03 13.7 0.9 0.91 8.9 0.0 2.8 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Pox_A32 PF04665.12 AIM22810.1 - 0.043 13.3 3.1 1.7 8.0 0.0 2.7 3 0 0 3 3 3 0 Poxvirus A32 protein AAA_33 PF13671.6 AIM22810.1 - 0.075 13.2 1.2 16 5.7 0.0 3.0 2 2 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 AIM22810.1 - 0.078 12.7 2.8 5.8 6.6 0.0 3.7 4 0 0 4 4 4 0 Sigma-54 interaction domain NACHT PF05729.12 AIM22810.1 - 0.13 12.2 4.4 5.3 6.9 0.0 3.5 3 0 0 3 3 3 0 NACHT domain APS_kinase PF01583.20 AIM22810.1 - 0.14 12.0 0.2 5.4 6.9 0.1 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase PRK PF00485.18 AIM22810.1 - 0.15 11.8 0.0 8.9 6.0 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 AIM22810.1 - 0.17 12.4 0.0 2.9 8.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 AIM22810.1 - 0.19 11.5 2.6 6.3 6.5 0.1 3.5 2 2 0 2 2 2 0 DEAD/DEAH box helicase YejG PF13989.6 AIM22811.1 - 5.5e-54 181.1 0.0 6.2e-54 180.9 0.0 1.0 1 0 0 1 1 1 1 YejG-like protein DUF3223 PF11523.8 AIM22811.1 - 0.071 14.0 0.0 0.11 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3223) MFS_1 PF07690.16 AIM22812.1 - 2.8e-46 158.1 49.3 2.8e-46 158.1 49.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AIM22812.1 - 7e-12 44.9 40.0 1.2e-11 44.2 13.3 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 AIM22812.1 - 0.0056 16.0 34.7 0.013 14.8 34.9 1.5 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB PseudoU_synth_2 PF00849.22 AIM22813.1 - 3.4e-19 69.5 0.1 7.4e-19 68.4 0.1 1.6 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 AIM22813.1 - 8.5e-09 35.0 0.2 1.5e-08 34.2 0.2 1.4 1 0 0 1 1 1 1 S4 domain Herpes_ORF11 PF04797.13 AIM22813.1 - 0.012 14.5 0.0 0.016 14.0 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus dUTPase protein ResIII PF04851.15 AIM22814.1 - 1.2e-25 90.5 0.0 1.9e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 AIM22814.1 - 1.1e-12 48.2 0.0 4.2e-12 46.4 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 AIM22814.1 - 7.1e-08 32.4 0.1 1.2e-06 28.4 0.0 2.6 2 1 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 AIM22814.1 - 7.6e-08 32.3 0.0 1.3e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_30 PF13604.6 AIM22814.1 - 0.00046 20.0 0.0 0.00086 19.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain zinc_ribbon_2 PF13240.6 AIM22814.1 - 0.00081 19.0 12.4 0.027 14.2 3.1 3.2 3 0 0 3 3 3 2 zinc-ribbon domain zf-tcix PF14952.6 AIM22814.1 - 0.0015 18.1 4.3 0.0019 17.8 0.1 2.4 2 0 0 2 2 2 1 Putative treble-clef, zinc-finger, Zn-binding AAA_16 PF13191.6 AIM22814.1 - 0.01 16.2 1.1 0.033 14.6 0.5 2.2 2 1 0 2 2 2 0 AAA ATPase domain DZR PF12773.7 AIM22814.1 - 0.011 15.7 2.3 0.011 15.7 2.3 2.7 3 0 0 3 3 2 0 Double zinc ribbon zf-ribbon_3 PF13248.6 AIM22814.1 - 0.02 14.3 8.8 0.31 10.5 3.6 2.8 2 1 1 3 3 3 0 zinc-ribbon domain AAA_22 PF13401.6 AIM22814.1 - 0.029 14.7 0.1 0.11 12.8 0.1 1.9 1 1 0 1 1 1 0 AAA domain SNF2_N PF00176.23 AIM22814.1 - 0.078 11.7 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA PF00004.29 AIM22814.1 - 0.089 13.2 0.0 0.38 11.2 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 AIM22814.1 - 0.16 11.2 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) UPF0547 PF10571.9 AIM22814.1 - 0.44 10.7 12.2 0.69 10.0 5.1 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-RanBP PF00641.18 AIM22814.1 - 0.83 9.0 5.1 0.61 9.4 1.8 2.1 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others QslA_E PF18226.1 AIM22814.1 - 0.84 9.6 3.6 1.4 8.9 0.5 2.7 2 1 1 3 3 3 0 LasR-specific antiactivator QslA chain E Ribosomal_L25p PF01386.19 AIM22815.1 - 1.1e-24 86.7 0.1 1.2e-24 86.6 0.1 1.0 1 0 0 1 1 1 1 Ribosomal L25p family DUF348 PF03990.14 AIM22815.1 - 0.19 11.5 1.3 0.41 10.4 1.3 1.6 1 0 0 1 1 1 0 G5-linked-Ubiquitin-like domain NA37 PF04245.13 AIM22816.1 - 2e-93 313.3 0.0 2.2e-93 313.1 0.0 1.0 1 0 0 1 1 1 1 37-kD nucleoid-associated bacterial protein Pox_ATPase-GT PF10640.9 AIM22816.1 - 0.17 10.7 0.9 0.31 9.9 0.1 1.7 3 0 0 3 3 3 0 mRNA capping enzyme N-terminal, ATPase and guanylyltransferase DUF1414 PF07208.11 AIM22817.1 - 6e-24 83.8 0.6 8.2e-24 83.3 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1414) DUF3413 PF11893.8 AIM22818.1 - 1.1e-107 358.9 8.5 1.5e-107 358.4 8.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3413) Sulfatase PF00884.23 AIM22818.1 - 1e-30 107.2 0.2 1.9e-30 106.3 0.2 1.4 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 AIM22818.1 - 2.7e-08 33.8 0.0 7.3e-05 22.5 0.0 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.12 AIM22818.1 - 6.8e-05 22.1 0.1 0.00011 21.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) DUF229 PF02995.17 AIM22818.1 - 0.00017 20.4 0.0 0.00035 19.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.18 AIM22818.1 - 0.18 11.1 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily LMBR1 PF04791.16 AIM22818.1 - 1.4 7.7 6.7 1.8 7.4 6.1 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein GST_N_3 PF13417.6 AIM22819.1 - 1.9e-15 57.0 0.0 3.9e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 AIM22819.1 - 7.5e-13 48.6 0.0 1.5e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AIM22819.1 - 2.5e-11 43.7 0.0 4.8e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 AIM22819.1 - 1.1e-07 31.8 0.0 3.5e-07 30.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 AIM22819.1 - 2.7e-07 30.7 0.0 4.1e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 AIM22819.1 - 0.00068 19.8 0.0 0.0021 18.2 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain FAA_hydrolase PF01557.18 AIM22820.1 - 4e-48 164.0 0.0 4.5e-48 163.8 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Cupin_2 PF07883.11 AIM22821.1 - 5.2e-31 106.2 0.3 1.9e-24 85.2 0.2 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 AIM22821.1 - 8.5e-09 35.0 0.1 0.011 15.4 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 AIM22821.1 - 1.3e-07 31.6 0.2 0.00026 20.9 0.1 2.5 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_1 PF00190.22 AIM22821.1 - 0.0033 17.0 0.0 0.19 11.3 0.0 2.2 2 0 0 2 2 2 1 Cupin ARD PF03079.14 AIM22821.1 - 0.045 13.9 0.0 0.079 13.1 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family CENP-C_C PF11699.8 AIM22821.1 - 0.076 13.2 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Mif2/CENP-C like MFS_1 PF07690.16 AIM22822.1 - 9.7e-52 176.0 58.5 4.5e-36 124.5 20.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AIM22822.1 - 7.3e-31 107.5 29.3 1.6e-26 93.2 4.0 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 AIM22822.1 - 1.7e-09 37.5 28.7 2.8e-09 36.8 6.9 2.1 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Saf_2TM PF18303.1 AIM22822.1 - 0.24 11.0 0.9 2.9 7.4 0.1 2.6 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain P5-ATPase PF12409.8 AIM22822.1 - 0.84 9.7 3.6 3 8.0 0.6 2.9 3 0 0 3 3 3 0 P5-type ATPase cation transporter HTH_1 PF00126.27 AIM22823.1 - 2.4e-16 59.4 0.0 5.3e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 AIM22823.1 - 3.9e-05 23.1 0.0 6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_28 PF13518.6 AIM22823.1 - 0.0057 16.8 0.0 0.033 14.3 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 AIM22823.1 - 0.03 14.1 0.0 0.15 11.9 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain MarR PF01047.22 AIM22823.1 - 0.034 14.1 0.1 0.12 12.3 0.1 2.0 1 0 0 1 1 1 0 MarR family DUF2089 PF09862.9 AIM22823.1 - 0.043 13.9 0.0 0.066 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) P22_Cro PF14549.6 AIM22823.1 - 0.06 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro HTH_5 PF01022.20 AIM22823.1 - 0.095 12.6 1.7 0.32 10.9 0.0 2.7 3 1 1 4 4 4 0 Bacterial regulatory protein, arsR family HTH_3 PF01381.22 AIM22823.1 - 0.097 12.7 0.1 0.33 11.0 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix HTH_Tnp_ISL3 PF13542.6 AIM22823.1 - 0.13 11.7 0.1 2.2 7.7 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_Tnp_1 PF01527.20 AIM22823.1 - 0.18 12.2 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Transposase LysR_substrate PF03466.20 AIM22824.1 - 8.7e-07 28.5 0.0 9.6e-07 28.4 0.0 1.0 1 0 0 1 1 1 1 LysR substrate binding domain DinI PF06183.13 AIM22825.1 - 1.1e-22 80.1 0.2 1.4e-22 79.7 0.2 1.1 1 0 0 1 1 1 1 DinI-like family Arb2 PF09757.9 AIM22825.1 - 0.069 12.3 0.0 0.069 12.3 0.0 1.1 1 0 0 1 1 1 0 Arb2 domain DUF3182 PF11379.8 AIM22825.1 - 0.13 11.2 0.0 0.13 11.2 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3182) phage_tail_N PF08400.10 AIM22826.1 - 1.9e-32 112.1 0.2 3.9e-32 111.0 0.2 1.5 1 0 0 1 1 1 1 Prophage tail fibre N-terminal CarboxypepD_reg PF13620.6 AIM22826.1 - 5.3e-07 29.8 2.1 1.2e-06 28.6 0.4 2.6 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 AIM22826.1 - 0.00047 20.1 0.0 0.0035 17.3 0.0 2.4 2 0 0 2 2 2 1 CarboxypepD_reg-like domain Big_1 PF02369.16 AIM22826.1 - 0.0027 17.7 0.4 0.69 10.0 0.0 3.0 2 0 0 2 2 2 2 Bacterial Ig-like domain (group 1) PmbA_TldD PF01523.16 AIM22826.1 - 0.0039 17.1 2.5 0.0077 16.1 0.7 2.4 2 1 0 2 2 2 1 Putative modulator of DNA gyrase Peptidase_S74 PF13884.6 AIM22827.1 - 2.1e-05 24.8 0.0 5.8e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Chaperone of endosialidase DUF1983 PF09327.11 AIM22828.1 - 7.5e-22 77.2 1.1 7.5e-22 77.2 1.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1983) Phage-tail_3 PF13550.6 AIM22828.1 - 2.5e-20 73.0 0.1 7.3e-20 71.5 0.1 1.8 1 0 0 1 1 1 1 Putative phage tail protein DUF3672 PF12421.8 AIM22828.1 - 2.7e-08 33.8 1.7 2.7e-08 33.8 1.7 2.4 2 0 0 2 2 2 1 Fibronectin type III protein F5_F8_type_C PF00754.25 AIM22828.1 - 0.047 13.8 0.8 0.51 10.5 0.0 3.1 2 1 1 3 3 3 0 F5/8 type C domain Lambda_tail_I PF06805.12 AIM22829.1 - 2.7e-05 24.4 0.0 0.00025 21.3 0.0 2.1 2 0 0 2 2 2 1 Bacteriophage lambda tail assembly protein I NLPC_P60 PF00877.19 AIM22830.1 - 1.3e-17 63.7 0.0 2.1e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 NlpC/P60 family Prok-JAB PF14464.6 AIM22830.1 - 3.1e-17 62.4 0.3 5.7e-17 61.6 0.3 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Phage_tail_L PF05100.12 AIM22831.1 - 5.4e-75 251.2 0.0 6.1e-75 251.0 0.0 1.0 1 0 0 1 1 1 1 Phage minor tail protein L Phage_min_tail PF05939.13 AIM22832.1 - 1.1e-34 119.0 0.0 1.2e-34 118.9 0.0 1.0 1 0 0 1 1 1 1 Phage minor tail protein DUF910 PF06014.11 AIM22833.1 - 0.022 14.8 1.5 0.6 10.2 0.1 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF910) RNA_pol_3_Rpc31 PF11705.8 AIM22833.1 - 0.18 12.0 2.3 0.49 10.6 2.3 1.8 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DIT1_PvcA PF05141.12 AIM22833.1 - 0.6 9.5 6.4 2.2 7.6 5.3 2.3 2 0 0 2 2 2 0 Pyoverdine/dityrosine biosynthesis protein Tape_meas_lam_C PF09718.10 AIM22833.1 - 4.4 7.5 10.9 0.17 12.1 0.8 3.7 3 0 0 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Phage_TAC_14 PF16462.5 AIM22835.1 - 1.8e-40 137.7 1.1 2e-40 137.5 1.1 1.0 1 0 0 1 1 1 1 Phage tail assembly chaperone protein, TAC PSD5 PF07637.11 AIM22835.1 - 0.034 14.5 0.0 0.059 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1595) Phage_TTP_13 PF16463.5 AIM22836.1 - 6.7e-71 236.2 0.4 7.6e-71 236.0 0.4 1.0 1 0 0 1 1 1 1 Phage tail tube protein family Phage_tail_3 PF08813.11 AIM22836.1 - 0.00047 19.8 0.0 0.00057 19.5 0.0 1.1 1 0 0 1 1 1 1 Phage tail tube protein, TTP Fn3-like PF14310.6 AIM22836.1 - 0.0029 17.7 0.0 0.0043 17.1 0.0 1.3 1 0 0 1 1 1 1 Fibronectin type III-like domain Neocarzinostat PF00960.18 AIM22836.1 - 0.066 13.2 1.5 0.069 13.1 0.4 1.6 2 0 0 2 2 2 0 Neocarzinostatin family Phage_lysozyme PF00959.19 AIM22839.1 - 1.6e-20 73.6 0.0 1.9e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Phage lysozyme Phage_holin_3_3 PF16083.5 AIM22840.1 - 6.2e-13 48.7 6.8 7.1e-13 48.5 6.8 1.1 1 0 0 1 1 1 1 LydA holin phage, holin superfamily III Phage_holin_3_1 PF05106.12 AIM22840.1 - 0.087 13.3 1.0 0.099 13.1 1.0 1.1 1 0 0 1 1 1 0 Phage holin family (Lysis protein S) EutK_C PF16365.5 AIM22840.1 - 0.14 12.2 0.1 0.29 11.2 0.1 1.7 1 1 0 1 1 1 0 Ethanolamine utilization protein EutK C-terminus Phage_antitermQ PF06530.12 AIM22841.1 - 3.5e-50 168.8 0.0 4.4e-50 168.5 0.0 1.1 1 0 0 1 1 1 1 Phage antitermination protein Q HTH_7 PF02796.15 AIM22841.1 - 0.015 15.3 0.2 0.042 13.9 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase DUF1133 PF06576.11 AIM22841.1 - 0.043 13.2 0.0 0.059 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1133) Sigma70_r4_2 PF08281.12 AIM22841.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 YdaS_antitoxin PF15943.5 AIM22842.1 - 3.8e-05 23.5 0.0 0.00022 21.0 0.0 2.2 2 0 0 2 2 2 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Peptidase_S24 PF00717.23 AIM22842.1 - 0.0014 18.6 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like HTH_3 PF01381.22 AIM22842.1 - 0.0021 18.1 0.1 0.08 13.0 0.0 3.0 2 1 0 2 2 2 1 Helix-turn-helix HTH_31 PF13560.6 AIM22842.1 - 0.02 15.2 0.1 2.8 8.3 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Phage_CI_repr PF07022.13 AIM22842.1 - 0.069 13.3 0.0 0.094 12.8 0.0 1.4 1 1 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain SmpA_OmlA PF04355.13 AIM22843.1 - 8.5e-14 51.1 0.1 1.2e-13 50.7 0.1 1.2 1 0 0 1 1 1 1 SmpA / OmlA family DUF4223 PF13978.6 AIM22843.1 - 0.095 12.7 1.7 2.8 8.0 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4223) DUF1348 PF07080.11 AIM22844.1 - 3.9e-64 214.4 5.5 4.4e-64 214.2 5.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 AIM22844.1 - 4.3e-07 30.5 1.4 5.9e-07 30.1 1.4 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 AIM22844.1 - 0.00055 20.3 0.6 0.00083 19.7 0.6 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) TetR_N PF00440.23 AIM22845.1 - 2.8e-17 62.2 0.4 1e-14 54.1 0.0 2.3 2 0 0 2 2 2 2 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.6 AIM22845.1 - 0.037 14.3 3.3 0.065 13.4 2.1 1.9 2 0 0 2 2 2 0 BetI-type transcriptional repressor, C-terminal TetR_C_13 PF16925.5 AIM22845.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.6 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain HTH_7 PF02796.15 AIM22845.1 - 0.19 11.8 1.5 0.29 11.2 0.0 2.1 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase Glyoxalase PF00903.25 AIM22846.1 - 3.8e-10 40.1 0.1 4.3e-10 39.9 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 AIM22846.1 - 0.00028 20.8 0.0 0.0024 17.8 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 AIM22846.1 - 0.0025 18.6 0.1 0.0031 18.3 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Porin_1 PF00267.21 AIM22847.1 - 6e-128 427.0 35.4 6.8e-128 426.9 35.4 1.0 1 0 0 1 1 1 1 Gram-negative porin DUF4186 PF13811.6 AIM22848.1 - 5.2e-48 161.6 0.0 6e-48 161.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4186) MFS_1 PF07690.16 AIM22849.1 - 3.7e-17 62.3 84.7 6.4e-13 48.4 49.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 AIM22849.1 - 0.04 12.3 33.7 0.065 11.6 14.2 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector RcsD_ABL PF16359.5 AIM22850.1 - 4.2e-38 129.6 0.3 7.2e-37 125.7 0.3 2.9 2 0 0 2 2 2 1 RcsD-ABL domain HATPase_c PF02518.26 AIM22850.1 - 2.1e-14 54.0 0.0 3.8e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Hpt PF01627.23 AIM22850.1 - 7.2e-10 39.0 0.0 7.2e-10 39.0 0.0 3.5 4 1 0 4 4 4 1 Hpt domain RcsC PF09456.10 AIM22850.1 - 0.051 13.6 0.1 0.19 11.7 0.1 2.0 1 0 0 1 1 1 0 RcsC Alpha-Beta-Loop (ABL) COMMD1_N PF17221.3 AIM22850.1 - 0.081 13.2 0.1 0.48 10.8 0.0 2.3 2 0 0 2 2 2 0 COMMD1 N-terminal domain Response_reg PF00072.24 AIM22851.1 - 4.1e-25 88.1 0.1 6.6e-25 87.5 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AIM22851.1 - 7.1e-19 67.1 0.3 1.2e-18 66.4 0.3 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AIM22851.1 - 6.9e-05 22.4 0.2 0.00016 21.3 0.2 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AIM22851.1 - 7.6e-05 22.2 0.1 0.00016 21.1 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 AIM22851.1 - 0.00084 19.0 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AIM22851.1 - 0.0015 18.2 0.0 0.0039 16.9 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain DUF2121 PF09894.9 AIM22851.1 - 0.042 13.4 0.0 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2121) DUF2357 PF09823.9 AIM22851.1 - 0.13 11.5 0.0 0.43 9.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2357) HTH_29 PF13551.6 AIM22851.1 - 0.16 12.0 0.0 0.59 10.2 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn helix Response_reg PF00072.24 AIM22852.1 - 1.5e-30 105.7 0.1 2.8e-30 104.8 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain RcsC PF09456.10 AIM22852.1 - 1.2e-29 102.1 0.0 3.6e-29 100.6 0.0 1.9 1 0 0 1 1 1 1 RcsC Alpha-Beta-Loop (ABL) HATPase_c PF02518.26 AIM22852.1 - 5.8e-28 97.6 0.0 1.2e-27 96.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AIM22852.1 - 8.3e-17 61.0 0.3 3.1e-16 59.1 0.0 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 AIM22852.1 - 0.032 14.1 0.0 0.065 13.1 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AIM22852.1 - 0.47 10.4 1.9 0.72 9.8 0.0 2.2 3 0 0 3 3 3 0 Histidine kinase-like ATPase domain DNA_topoisoIV PF00521.20 AIM22853.1 - 6.5e-153 509.6 0.0 8.5e-153 509.2 0.0 1.1 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.13 AIM22853.1 - 9e-82 268.4 9.1 1e-15 56.9 0.1 6.4 6 0 0 6 6 6 6 DNA gyrase C-terminal domain, beta-propeller Methyltransf_23 PF13489.6 AIM22854.1 - 3.6e-25 88.7 0.0 7e-25 87.8 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AIM22854.1 - 9.3e-22 77.5 0.1 1.6e-21 76.8 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AIM22854.1 - 9.8e-19 67.6 0.0 1.4e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AIM22854.1 - 1.1e-18 67.8 0.1 1.6e-18 67.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIM22854.1 - 6.2e-15 55.8 0.0 9.5e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 AIM22854.1 - 1.1e-09 38.2 0.0 1.3e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) CMAS PF02353.20 AIM22854.1 - 2.8e-09 36.7 0.0 4e-09 36.2 0.0 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 AIM22854.1 - 2.7e-08 33.4 0.0 3.3e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 AIM22854.1 - 1.4e-06 28.0 0.0 1.9e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 AIM22854.1 - 1.5e-06 27.8 0.0 2.1e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 AIM22854.1 - 0.00054 19.0 0.0 0.00076 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MetW PF07021.12 AIM22854.1 - 0.0019 17.9 0.0 0.0027 17.3 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 AIM22854.1 - 0.0024 17.9 0.0 0.0029 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 AIM22854.1 - 0.0044 16.2 0.0 0.0068 15.5 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase GidB PF02527.15 AIM22854.1 - 0.057 12.7 0.3 0.31 10.4 0.3 2.0 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G TPMT PF05724.11 AIM22854.1 - 0.065 12.9 0.0 0.14 11.7 0.0 1.6 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) DFP PF04127.15 AIM22854.1 - 0.13 12.1 1.6 0.61 9.9 0.2 2.0 1 1 1 2 2 2 0 DNA / pantothenate metabolism flavoprotein Ribonuc_red_lgC PF02867.15 AIM22855.1 - 1.7e-119 399.8 0.0 3.2e-117 392.2 0.0 2.5 2 1 0 2 2 2 1 Ribonucleotide reductase, barrel domain ATP-cone PF03477.16 AIM22855.1 - 2.4e-16 60.1 0.3 6.6e-16 58.7 0.3 1.8 1 0 0 1 1 1 1 ATP cone domain Ribonuc_red_lgN PF00317.21 AIM22855.1 - 1.3e-13 50.8 0.9 2.1e-13 50.0 0.1 1.9 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain Ribonuc_red_sm PF00268.21 AIM22856.1 - 5.2e-47 160.6 1.2 6.9e-47 160.2 1.2 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Flavodoxin_5 PF12724.7 AIM22856.1 - 0.052 13.8 0.8 0.2 11.9 0.1 2.0 2 0 0 2 2 2 0 Flavodoxin domain ARL2_Bind_BART PF11527.8 AIM22856.1 - 0.056 13.5 0.7 0.92 9.6 0.0 2.4 2 0 0 2 2 2 0 The ARF-like 2 binding protein BART Fer2 PF00111.27 AIM22857.1 - 3e-09 36.7 4.2 3.4e-09 36.5 4.2 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain HOK_GEF PF01848.16 AIM22858.1 - 5.7e-13 48.0 4.6 6.8e-13 47.8 4.6 1.1 1 0 0 1 1 1 1 Hok/gef family Sarcolipin PF05366.11 AIM22858.1 - 0.026 14.2 0.9 0.026 14.2 0.9 1.6 2 0 0 2 2 2 0 Sarcolipin FixS PF03597.15 AIM22858.1 - 0.059 13.1 0.1 0.091 12.5 0.1 1.3 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type HTH_18 PF12833.7 AIM22859.1 - 1e-20 73.8 0.2 1.8e-20 72.9 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AIM22859.1 - 3.4e-09 36.6 0.0 8.3e-06 25.8 0.0 2.3 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family AraC_binding PF02311.19 AIM22859.1 - 0.0012 18.8 2.3 0.0055 16.6 1.5 2.3 1 1 1 2 2 2 1 AraC-like ligand binding domain HTH_23 PF13384.6 AIM22859.1 - 0.078 12.8 0.9 1.3 8.9 0.1 2.7 3 0 0 3 3 3 0 Homeodomain-like domain 23S_rRNA_IVP PF05635.11 AIM22859.1 - 0.11 12.9 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 23S rRNA-intervening sequence protein FAD_binding_3 PF01494.19 AIM22860.1 - 1.4e-16 60.7 0.5 6.5e-16 58.5 0.5 1.8 1 1 0 1 1 1 1 FAD binding domain MoCF_biosynth PF00994.24 AIM22861.1 - 2.5e-30 105.0 0.0 3.9e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain CinA_KH PF18146.1 AIM22861.1 - 0.038 14.1 0.0 0.099 12.8 0.0 1.7 1 0 0 1 1 1 0 Damage-inducible protein CinA KH domain CinA PF02464.17 AIM22861.1 - 0.16 11.5 0.7 1.1 8.9 0.0 2.2 2 1 0 2 2 2 0 Competence-damaged protein Trp_Tyr_perm PF03222.13 AIM22862.1 - 1.5e-134 449.0 28.8 1.7e-134 448.8 28.8 1.0 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family Aa_trans PF01490.18 AIM22862.1 - 7.9e-11 41.3 18.0 7.9e-11 41.3 18.0 2.2 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 AIM22862.1 - 1.3e-09 37.5 37.3 1.4e-08 34.0 37.3 1.9 1 1 0 1 1 1 1 Amino acid permease Sugarporin_N PF11471.8 AIM22863.1 - 0.015 15.3 0.4 0.023 14.6 0.4 1.2 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension TRAF_BIRC3_bd PF16673.5 AIM22863.1 - 0.036 13.8 0.1 0.062 13.1 0.1 1.4 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain PKcGMP_CC PF16808.5 AIM22863.1 - 0.053 13.4 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Pox_A_type_inc PF04508.12 AIM22863.1 - 0.18 11.7 0.4 0.41 10.6 0.4 1.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat rve PF00665.26 AIM22864.1 - 1.2e-26 93.2 0.1 2.1e-26 92.5 0.1 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 AIM22864.1 - 2.8e-20 71.9 0.0 5.8e-20 70.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 AIM22864.1 - 0.00086 19.6 0.0 0.0017 18.6 0.0 1.5 1 0 0 1 1 1 1 DDE domain HTH_21 PF13276.6 AIM22864.1 - 0.0028 17.8 1.6 0.0061 16.7 0.7 2.0 2 0 0 2 2 2 1 HTH-like domain rve_2 PF13333.6 AIM22864.1 - 0.0055 16.9 0.0 0.01 16.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DUF4802 PF16060.5 AIM22864.1 - 0.079 13.1 0.9 0.16 12.2 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4802) YfaZ PF07437.11 AIM22865.1 - 6.7e-70 234.4 1.9 7.5e-70 234.2 1.9 1.0 1 0 0 1 1 1 1 YfaZ precursor PQQ PF01011.21 AIM22865.1 - 0.016 15.1 0.0 0.034 14.1 0.0 1.6 1 0 0 1 1 1 0 PQQ enzyme repeat LptD PF04453.14 AIM22865.1 - 0.023 13.9 0.0 0.03 13.5 0.0 1.2 1 0 0 1 1 1 0 LPS transport system D Catalase PF00199.19 AIM22866.1 - 2.2e-186 619.6 0.2 2.5e-186 619.3 0.2 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 AIM22866.1 - 7.7e-23 80.5 0.0 1.5e-22 79.5 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive AMP-binding PF00501.28 AIM22867.1 - 1e-53 182.5 0.0 1.9e-53 181.6 0.0 1.4 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AIM22867.1 - 1.4e-06 29.2 0.0 2.6e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain IGR PF09597.10 AIM22867.1 - 0.14 12.2 0.2 0.93 9.6 0.0 2.2 2 0 0 2 2 2 0 IGR protein motif MR_MLE_C PF13378.6 AIM22868.1 - 7.5e-16 58.4 0.3 1.1e-15 57.8 0.3 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like Enolase_like_N PF18374.1 AIM22868.1 - 0.019 14.4 0.7 0.088 12.2 0.2 2.3 2 0 0 2 2 2 0 Enolase N-terminal domain-like ECH_1 PF00378.20 AIM22869.1 - 5.9e-80 268.2 0.0 7.1e-80 267.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AIM22869.1 - 3.7e-22 79.3 0.2 4.6e-22 79.0 0.2 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF1666 PF07891.12 AIM22869.1 - 0.12 12.1 0.1 0.17 11.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1666) SDH_sah PF01972.16 AIM22869.1 - 0.19 10.7 0.0 0.29 10.1 0.0 1.2 1 0 0 1 1 1 0 Serine dehydrogenase proteinase Abhydrolase_6 PF12697.7 AIM22870.1 - 2.5e-19 70.7 5.4 3e-19 70.5 5.4 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AIM22870.1 - 3.6e-12 46.5 0.3 7.7e-12 45.4 0.3 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AIM22870.1 - 2.1e-07 30.5 0.0 5.6e-07 29.1 0.0 1.6 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 AIM22870.1 - 1.3e-06 28.7 0.0 1.7e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain DLH PF01738.18 AIM22870.1 - 0.051 13.1 0.0 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF2974 PF11187.8 AIM22870.1 - 0.086 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF676 PF05057.14 AIM22870.1 - 0.13 11.7 0.0 0.34 10.4 0.0 1.5 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.7 AIM22870.1 - 0.21 11.3 0.0 0.33 10.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family TPP_enzyme_M_2 PF16582.5 AIM22871.1 - 8.7e-87 290.2 6.6 1.2e-86 289.7 6.6 1.2 1 0 0 1 1 1 1 Middle domain of thiamine pyrophosphate TPP_enzyme_N PF02776.18 AIM22871.1 - 6.9e-28 97.4 1.3 1.4e-26 93.1 0.2 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 AIM22871.1 - 3.6e-08 33.4 0.0 1.3e-07 31.5 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Peripla_BP_3 PF13377.6 AIM22871.1 - 0.33 11.3 3.4 1.3 9.4 0.3 3.1 2 1 1 3 3 3 0 Periplasmic binding protein-like domain DUF883 PF05957.13 AIM22872.1 - 1e-27 96.5 0.2 1.2e-27 96.3 0.2 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 AIM22872.1 - 0.0095 16.5 4.5 0.18 12.4 0.3 2.5 2 1 0 2 2 2 2 YtxH-like protein SbcD_C PF12320.8 AIM22872.1 - 0.012 15.9 0.1 0.019 15.2 0.1 1.3 1 0 0 1 1 1 0 Type 5 capsule protein repressor C-terminal domain ADH_N PF08240.12 AIM22873.1 - 4.3e-27 94.2 0.6 7.8e-27 93.3 0.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AIM22873.1 - 1.8e-21 76.5 0.0 2.9e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 AIM22873.1 - 1.3e-05 24.8 0.0 2.1e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 AIM22873.1 - 5.3e-05 24.3 0.0 0.00012 23.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.20 AIM22873.1 - 0.065 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 AIM22873.1 - 0.15 11.4 0.3 0.28 10.5 0.3 1.4 1 0 0 1 1 1 0 ThiF family 2-Hacid_dh_C PF02826.19 AIM22873.1 - 0.15 11.4 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.25 AIM22874.1 - 3.3e-63 212.7 0.2 3.8e-63 212.5 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AIM22874.1 - 2.7e-62 210.4 0.7 3.1e-62 210.2 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AIM22874.1 - 4.4e-15 56.1 0.2 6e-15 55.6 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AIM22874.1 - 0.0018 17.8 0.7 0.0086 15.6 0.7 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family CHASE2 PF05226.11 AIM22874.1 - 0.11 12.1 0.1 0.2 11.4 0.1 1.6 1 1 0 1 1 1 0 CHASE2 domain Peripla_BP_3 PF13377.6 AIM22875.1 - 6.4e-26 91.7 1.5 5.3e-25 88.7 0.2 2.3 2 1 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 AIM22875.1 - 4.7e-25 88.6 0.0 6.2e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 AIM22875.1 - 1.5e-16 59.9 0.1 2.8e-16 59.0 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 AIM22875.1 - 1.6e-15 57.4 0.0 2.2e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain HTH_Crp_2 PF13545.6 AIM22875.1 - 0.013 15.5 0.5 0.052 13.5 0.0 2.3 3 0 0 3 3 3 0 Crp-like helix-turn-helix domain HTH_IclR PF09339.10 AIM22875.1 - 0.017 14.9 0.2 0.048 13.5 0.0 1.9 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_23 PF13384.6 AIM22875.1 - 0.018 14.8 0.1 0.32 10.9 0.0 2.8 3 0 0 3 3 3 0 Homeodomain-like domain HTH_10 PF04967.12 AIM22875.1 - 0.029 14.2 0.0 0.082 12.7 0.0 1.8 1 0 0 1 1 1 0 HTH DNA binding domain HTH_3 PF01381.22 AIM22875.1 - 0.041 13.9 0.0 0.096 12.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix HTH_31 PF13560.6 AIM22875.1 - 0.044 14.1 0.0 0.096 13.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.6 AIM22875.1 - 0.053 13.1 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR PF01047.22 AIM22875.1 - 0.083 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 MarR family Crp PF00325.20 AIM22875.1 - 0.09 12.4 0.1 0.27 10.9 0.1 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family Sigma70_r4 PF04545.16 AIM22875.1 - 0.1 12.2 0.0 0.26 10.8 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 CSTF2_hinge PF14327.6 AIM22875.1 - 0.13 12.7 0.0 1.3 9.5 0.0 2.2 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 DUF1097 PF06496.11 AIM22876.1 - 2.5e-36 125.0 27.3 2.9e-36 124.8 27.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1097) MFS_1 PF07690.16 AIM22877.1 - 6.8e-20 71.3 51.6 6.8e-20 71.3 51.6 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 AIM22877.1 - 1.2e-06 27.7 27.8 1.3e-05 24.3 9.4 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter LysR_substrate PF03466.20 AIM22878.1 - 4.6e-37 127.4 2.1 5.7e-37 127.1 2.1 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM22878.1 - 6.2e-15 54.9 0.1 1.5e-14 53.6 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family Proton_antipo_M PF00361.20 AIM22879.1 - 9.3e-84 281.1 27.2 1.9e-83 280.0 27.2 1.5 1 0 0 1 1 1 1 Proton-conducting membrane transporter NADHdeh_related PF10125.9 AIM22879.1 - 0.0002 20.8 4.6 0.0002 20.8 4.6 2.3 2 1 0 2 2 2 1 NADH dehydrogenase I, subunit N related protein Proton_antipo_M PF00361.20 AIM22880.1 - 2.4e-71 240.4 24.6 4.4e-71 239.5 24.6 1.4 1 0 0 1 1 1 1 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 AIM22880.1 - 0.13 12.3 0.1 0.13 12.3 0.1 3.3 3 0 0 3 3 3 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Proton_antipo_M PF00361.20 AIM22881.1 - 3.7e-96 321.8 24.6 3.7e-96 321.8 24.6 3.3 2 1 1 3 3 3 1 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 AIM22881.1 - 9.1e-22 76.9 3.5 9.1e-22 76.9 3.5 3.1 2 0 0 2 2 2 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus NADH5_C PF06455.11 AIM22881.1 - 0.00026 20.6 0.1 0.00026 20.6 0.1 2.3 2 0 0 2 2 2 1 NADH dehydrogenase subunit 5 C-terminus Oxidored_q2 PF00420.24 AIM22882.1 - 2.4e-21 75.3 7.8 2.8e-21 75.1 7.8 1.0 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L NAD4L PF06235.11 AIM22882.1 - 0.0021 18.0 1.4 0.0028 17.6 1.4 1.2 1 0 0 1 1 1 1 NADH dehydrogenase subunit 4L (NAD4L) ATP1G1_PLM_MAT8 PF02038.16 AIM22882.1 - 0.017 14.6 0.6 0.017 14.6 0.6 2.0 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family DUF5392 PF17370.2 AIM22882.1 - 0.45 10.6 1.7 0.49 10.5 1.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5392) Gram_pos_anchor PF00746.21 AIM22882.1 - 1.5 8.8 8.8 5.7 7.0 1.3 3.1 3 0 0 3 3 3 0 LPXTG cell wall anchor motif Oxidored_q3 PF00499.20 AIM22883.1 - 7.9e-33 113.2 18.3 1e-32 112.9 18.3 1.1 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 PIRT PF15099.6 AIM22883.1 - 0.17 11.4 6.1 1.2 8.7 1.3 2.3 1 1 1 2 2 2 0 Phosphoinositide-interacting protein family ABC2_membrane_3 PF12698.7 AIM22883.1 - 0.72 8.9 15.8 0.9 8.6 15.8 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Fer4 PF00037.27 AIM22884.1 - 2.1e-14 52.6 16.6 7e-09 35.1 0.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 AIM22884.1 - 3.1e-12 46.9 10.7 5e-12 46.2 10.7 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 AIM22884.1 - 3.3e-10 39.9 8.2 5.4e-05 23.3 4.1 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AIM22884.1 - 5.5e-10 40.0 6.2 0.00013 22.8 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 AIM22884.1 - 9.7e-10 38.4 19.2 1.5e-06 28.2 12.2 1.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 AIM22884.1 - 7.6e-09 35.9 1.5 0.0013 19.2 0.0 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AIM22884.1 - 4.6e-08 33.1 10.2 1.2e-07 31.8 10.4 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 AIM22884.1 - 4.2e-06 26.5 12.4 0.01 15.8 0.9 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 AIM22884.1 - 2.9e-05 23.9 16.9 0.0046 17.0 0.9 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 AIM22884.1 - 0.00015 22.2 11.7 0.047 14.2 12.8 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 AIM22884.1 - 0.0011 19.3 13.4 0.068 13.7 1.2 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_13 PF13370.6 AIM22884.1 - 0.0055 17.2 9.7 0.53 10.9 1.4 2.6 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 AIM22884.1 - 0.0087 16.9 3.6 0.0087 16.9 3.6 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain ETF_QO PF05187.13 AIM22884.1 - 0.19 11.9 5.7 0.24 11.6 2.6 2.0 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_18 PF13746.6 AIM22884.1 - 0.22 11.7 10.7 13 6.0 10.7 2.2 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 AIM22884.1 - 0.47 11.3 14.0 2.9 8.8 1.9 2.2 1 1 2 3 3 3 0 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 AIM22884.1 - 9.2 6.6 7.7 2.5 8.4 0.6 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain NADHdh PF00146.21 AIM22885.1 - 2.7e-119 397.9 20.5 3.2e-119 397.7 20.5 1.0 1 0 0 1 1 1 1 NADH dehydrogenase NADH-G_4Fe-4S_3 PF10588.9 AIM22886.1 - 4.4e-15 54.9 0.2 1.2e-14 53.6 0.2 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2_4 PF13510.6 AIM22886.1 - 8.2e-12 45.0 0.8 1.9e-11 43.9 0.1 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Molybdop_Fe4S4 PF04879.16 AIM22886.1 - 5e-10 39.2 0.2 1.4e-09 37.8 0.2 1.8 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain Fer2 PF00111.27 AIM22886.1 - 1.2e-09 37.9 1.6 2.8e-09 36.8 0.2 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Molybdopterin PF00384.22 AIM22886.1 - 6.9e-08 31.9 0.0 1.7e-06 27.3 0.0 2.2 2 0 0 2 2 2 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 AIM22886.1 - 2e-07 31.0 0.0 5.4e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain TPP_enzyme_M PF00205.22 AIM22886.1 - 0.017 14.8 1.6 1.1 9.0 0.4 2.7 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Fer4_6 PF12837.7 AIM22886.1 - 1.7 8.8 9.0 0.25 11.5 0.6 3.3 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4 PF00037.27 AIM22886.1 - 7.4 6.6 9.6 1.5 8.8 0.5 2.9 3 0 0 3 3 3 0 4Fe-4S binding domain Complex1_51K PF01512.17 AIM22887.1 - 1.4e-50 171.2 0.0 1.9e-50 170.7 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 AIM22887.1 - 8.4e-27 93.1 0.0 1.4e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 AIM22887.1 - 9.5e-08 31.8 0.1 2.4e-07 30.5 0.1 1.7 1 0 0 1 1 1 1 SLBB domain CP12 PF02672.15 AIM22887.1 - 0.2 12.4 0.0 0.46 11.3 0.0 1.5 1 0 0 1 1 1 0 CP12 domain 2Fe-2S_thioredx PF01257.19 AIM22888.1 - 1.5e-50 170.8 0.0 1.8e-50 170.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Complex1_49kDa PF00346.19 AIM22889.1 - 6.9e-103 343.5 0.0 8.6e-103 343.1 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Complex1_30kDa PF00329.19 AIM22889.1 - 9.4e-43 145.7 0.2 2.4e-42 144.4 0.2 1.7 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Oxidored_q6 PF01058.22 AIM22890.1 - 2.2e-22 79.3 0.1 3.2e-22 78.8 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Oxidored_q4 PF00507.19 AIM22891.1 - 1.3e-31 108.7 1.8 1.4e-31 108.5 1.1 1.4 1 1 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 SCAMP PF04144.13 AIM22891.1 - 0.23 11.7 6.3 0.17 12.1 1.5 2.0 2 0 0 2 2 2 0 SCAMP family LysR_substrate PF03466.20 AIM22892.1 - 2.6e-30 105.3 0.5 3.7e-30 104.9 0.1 1.4 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AIM22892.1 - 2.2e-17 62.7 1.2 2.2e-17 62.7 1.2 1.9 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family Aminotran_1_2 PF00155.21 AIM22893.1 - 1.8e-48 165.6 0.0 2e-48 165.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 AIM22893.1 - 1.5e-05 24.5 0.0 2.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 AIM22893.1 - 0.00034 19.7 0.0 0.0012 17.9 0.0 1.8 1 1 1 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 AIM22893.1 - 0.057 12.7 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase HD_2 PF12917.7 AIM22894.1 - 5.1e-76 254.5 0.8 5.9e-76 254.3 0.8 1.0 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD_3 PF13023.6 AIM22894.1 - 4.9e-18 65.6 0.3 6e-18 65.3 0.3 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.22 AIM22894.1 - 6.9e-07 29.5 0.3 9.7e-07 29.0 0.3 1.2 1 0 0 1 1 1 1 HD domain DUF668 PF05003.12 AIM22894.1 - 0.056 13.9 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF668) CitMHS PF03600.16 AIM22895.1 - 4.9e-56 190.1 46.3 1.2e-34 119.9 15.3 2.1 2 0 0 2 2 2 2 Citrate transporter TrkA_C PF02080.21 AIM22895.1 - 5.2e-33 112.7 0.4 4.1e-18 65.0 0.1 2.4 2 0 0 2 2 2 2 TrkA-C domain Na_sulph_symp PF00939.19 AIM22895.1 - 7.8e-25 87.8 42.2 9.9e-14 51.2 13.1 3.3 2 2 1 3 3 3 3 Sodium:sulfate symporter transmembrane region DctM PF06808.12 AIM22895.1 - 1.3e-11 44.0 44.9 1.3e-07 30.9 19.5 2.8 2 1 0 2 2 2 2 Tripartite ATP-independent periplasmic transporter, DctM component HAD_2 PF13419.6 AIM22896.1 - 4.2e-26 92.1 0.0 5.2e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AIM22896.1 - 3.5e-16 60.1 0.1 3.3e-15 56.9 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AIM22896.1 - 9.7e-09 35.9 0.0 1.2e-08 35.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AIM22896.1 - 2.6e-06 27.4 0.0 5.1e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 AIM22896.1 - 0.00029 20.9 0.0 0.0015 18.6 0.0 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase YfbU PF03887.14 AIM22897.1 - 2.3e-66 222.9 0.9 2.6e-66 222.7 0.9 1.0 1 0 0 1 1 1 1 YfbU domain DUF412 PF04217.13 AIM22898.1 - 3e-60 202.2 0.3 3.4e-60 202.0 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF412 Acetate_kinase PF00871.17 AIM22899.1 - 8.4e-173 574.5 0.0 9.6e-173 574.3 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family BcrAD_BadFG PF01869.20 AIM22899.1 - 0.023 14.2 0.2 0.069 12.6 0.2 1.8 1 1 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family PTA_PTB PF01515.19 AIM22900.1 - 3.9e-127 424.0 0.3 5.9e-127 423.4 0.3 1.3 1 0 0 1 1 1 1 Phosphate acetyl/butaryl transferase AAA_26 PF13500.6 AIM22900.1 - 1.2e-55 188.4 0.1 2.2e-55 187.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain DRTGG PF07085.12 AIM22900.1 - 2.2e-29 101.3 0.0 7.2e-29 99.7 0.0 1.9 1 0 0 1 1 1 1 DRTGG domain PucR PF07905.11 AIM22900.1 - 0.021 15.1 0.0 0.073 13.4 0.0 1.9 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family GREB1 PF15782.5 AIM22902.1 - 0.0025 15.0 0.1 0.0029 14.9 0.1 1.0 1 0 0 1 1 1 1 Gene regulated by oestrogen in breast cancer Transketolase_C PF02780.20 AIM22903.1 - 5.1e-35 120.1 0.1 1e-34 119.1 0.1 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 AIM22903.1 - 9.5e-21 74.3 1.1 1.4e-20 73.8 1.1 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain PFOR_II PF17147.4 AIM22903.1 - 0.002 18.4 0.0 0.0046 17.2 0.0 1.6 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_N PF00456.21 AIM22904.1 - 2.1e-47 161.7 0.0 3.2e-47 161.1 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.6 AIM22904.1 - 3.3e-10 39.6 0.1 2.1e-07 30.5 0.0 2.4 2 1 0 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 AIM22904.1 - 3.4e-07 29.5 0.0 5.2e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 AIM22904.1 - 1.3e-05 25.1 0.2 9.1e-05 22.3 0.2 2.1 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain EIIC-GAT PF03611.14 AIM22905.1 - 6.2e-150 499.7 32.7 6.2e-150 499.7 32.7 1.4 2 0 0 2 2 2 1 PTS system sugar-specific permease component PTS_IIB PF02302.17 AIM22906.1 - 1.2e-17 64.3 1.6 1.4e-17 64.2 1.6 1.0 1 0 0 1 1 1 1 PTS system, Lactose/Cellobiose specific IIB subunit PTS_EIIA_2 PF00359.22 AIM22907.1 - 8e-36 123.1 0.0 8.9e-36 122.9 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 Peripla_BP_2 PF01497.18 AIM22907.1 - 0.012 15.2 0.0 0.017 14.7 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein Peripla_BP_3 PF13377.6 AIM22908.1 - 2.3e-27 96.4 0.1 6e-27 95.0 0.0 1.7 2 0 0 2 2 2 1 Periplasmic binding protein-like domain LacI PF00356.21 AIM22908.1 - 1.9e-18 66.0 0.0 3.7e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_1 PF00532.21 AIM22908.1 - 1.2e-17 64.3 0.1 1.6e-17 63.9 0.1 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family PCuAC PF04314.13 AIM22908.1 - 0.023 14.5 0.6 0.12 12.1 0.1 2.2 1 1 1 2 2 2 0 Copper chaperone PCu(A)C Nitro_FeMo-Co PF02579.17 AIM22908.1 - 0.18 12.2 0.0 0.77 10.1 0.0 2.0 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor HTH_Tnp_ISL3 PF13542.6 AIM22908.1 - 0.28 10.6 2.0 0.46 9.9 0.5 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 NUDIX PF00293.28 AIM22909.1 - 2.5e-19 69.6 0.3 4e-19 69.0 0.3 1.3 1 0 0 1 1 1 1 NUDIX domain Il2rg PF15874.5 AIM22909.1 - 0.037 14.3 0.0 0.059 13.6 0.0 1.3 1 0 0 1 1 1 0 Putative Interleukin 2 receptor, gamma chain Metallophos_2 PF12850.7 AIM22910.1 - 1.2e-24 87.3 0.0 1.6e-24 87.0 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 AIM22910.1 - 4.4e-12 46.9 0.0 1.2e-11 45.6 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.6 AIM22910.1 - 0.0089 15.4 0.0 0.017 14.5 0.0 1.5 2 0 0 2 2 2 1 Metallophosphoesterase, calcineurin superfamily GST_C PF00043.25 AIM22911.1 - 1.9e-13 50.4 0.0 3.3e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 AIM22911.1 - 1.6e-12 47.6 0.0 8.5e-12 45.3 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 AIM22911.1 - 1.3e-10 41.5 0.0 2.3e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AIM22911.1 - 3.1e-10 40.2 0.0 5.6e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 AIM22911.1 - 9.1e-08 32.0 0.0 2.2e-07 30.8 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 AIM22911.1 - 6.5e-06 26.3 0.0 9.9e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain FolB PF02152.18 AIM22912.1 - 3.7e-24 85.4 1.1 4.2e-24 85.2 1.1 1.0 1 0 0 1 1 1 1 Dihydroneopterin aldolase Bro-N PF02498.17 AIM22912.1 - 0.025 15.3 0.1 0.035 14.8 0.1 1.4 1 0 0 1 1 1 0 BRO family, N-terminal domain ETC_C1_NDUFA5 PF04716.14 AIM22912.1 - 0.056 13.3 0.2 0.85 9.5 0.1 2.3 2 0 0 2 2 2 0 ETC complex I subunit conserved region DUF1731 PF08338.11 AIM22913.1 - 3.3e-21 74.9 0.7 5.9e-21 74.0 0.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) Epimerase PF01370.21 AIM22913.1 - 4.9e-19 68.7 0.0 8.4e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 AIM22913.1 - 2.7e-05 23.9 0.0 7.5e-05 22.4 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 AIM22913.1 - 9.2e-05 22.0 0.0 0.0055 16.1 0.0 2.9 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 AIM22913.1 - 0.00047 19.4 0.0 0.0011 18.2 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.17 AIM22913.1 - 0.0016 17.6 0.0 0.0026 16.9 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 AIM22913.1 - 0.0019 18.1 0.1 0.0031 17.4 0.1 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 AIM22913.1 - 0.011 14.9 0.0 0.056 12.6 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein ABC_tran PF00005.27 AIM22914.1 - 8.1e-34 117.1 0.0 1.1e-33 116.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIM22914.1 - 1.9e-12 47.6 0.1 2.2e-06 27.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIM22914.1 - 5.3e-08 32.6 0.2 1.4e-07 31.2 0.2 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_13 PF13166.6 AIM22914.1 - 5.8e-05 21.9 0.0 0.064 11.9 0.0 2.1 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 AIM22914.1 - 7.2e-05 22.7 0.0 0.0069 16.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 AIM22914.1 - 0.00045 19.9 0.1 0.00086 19.0 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_ATPase PF09818.9 AIM22914.1 - 0.0069 15.2 0.0 0.8 8.4 0.0 2.3 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_16 PF13191.6 AIM22914.1 - 0.0092 16.4 0.0 0.022 15.2 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 AIM22914.1 - 0.011 15.1 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI G-alpha PF00503.20 AIM22914.1 - 0.012 14.8 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_23 PF13476.6 AIM22914.1 - 0.013 16.0 0.0 0.019 15.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 AIM22914.1 - 0.019 14.7 0.0 0.041 13.6 0.0 1.6 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family RsgA_GTPase PF03193.16 AIM22914.1 - 0.032 14.1 0.0 0.099 12.5 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 AIM22914.1 - 0.034 13.9 0.1 0.13 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 AIM22914.1 - 0.048 13.8 0.0 0.11 12.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 AIM22914.1 - 0.086 12.2 0.1 0.24 10.7 0.1 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.6 AIM22914.1 - 0.14 12.5 0.4 0.69 10.2 0.1 2.1 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.17 AIM22914.1 - 0.2 11.7 1.1 0.83 9.7 1.1 2.0 1 1 0 1 1 1 0 Helicase HerA, central domain BPD_transp_1 PF00528.22 AIM22915.1 - 9e-16 58.1 12.1 9e-16 58.1 12.1 1.3 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component Stevor PF17410.2 AIM22915.1 - 0.045 13.3 0.8 0.056 13.0 0.8 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF5379 PF17350.2 AIM22915.1 - 0.4 11.0 3.8 1.3 9.4 0.6 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5379) BPD_transp_1 PF00528.22 AIM22916.1 - 7e-18 65.0 10.4 7.9e-18 64.8 10.4 1.0 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component DUF4027 PF13219.6 AIM22917.1 - 0.2 11.6 3.4 0.33 10.8 3.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4027) SBP_bac_3 PF00497.20 AIM22918.1 - 9.2e-63 211.7 0.8 1.1e-62 211.5 0.8 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1 PF09084.11 AIM22918.1 - 7.5e-06 26.0 0.0 0.00073 19.5 0.0 2.1 1 1 1 2 2 2 2 NMT1/THI5 like Lig_chan-Glu_bd PF10613.9 AIM22918.1 - 4.5e-05 23.6 0.1 0.002 18.3 0.1 2.3 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site YhfZ_C PF14503.6 AIM22918.1 - 0.019 14.5 0.0 0.28 10.7 0.0 2.1 1 1 1 2 2 2 0 YhfZ C-terminal domain Methyltransf_31 PF13847.6 AIM22918.1 - 0.027 14.2 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 AIM22918.1 - 0.1 13.3 0.0 0.32 11.7 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain GA-like PF17573.2 AIM22918.1 - 0.21 11.5 1.9 0.6 10.1 1.9 1.8 1 0 0 1 1 1 0 GA-like domain Flavoprotein PF02441.19 AIM22919.1 - 2.8e-22 79.2 0.0 3.6e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein GATase_6 PF13522.6 AIM22920.1 - 2.7e-17 63.2 0.0 6.1e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 AIM22920.1 - 7.3e-16 58.2 0.0 1.7e-15 57.0 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 AIM22920.1 - 1.9e-08 34.0 0.0 3.7e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 AIM22920.1 - 1.5e-06 27.4 0.0 1.4e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferases class-II Colicin_V PF02674.16 AIM22921.1 - 5.3e-37 127.0 14.7 6.3e-37 126.7 14.7 1.0 1 0 0 1 1 1 1 Colicin V production protein Arch_flagellin PF01917.16 AIM22921.1 - 0.015 15.5 0.9 0.03 14.5 0.9 1.4 1 0 0 1 1 1 0 Archaebacterial flagellin Phage_holin_4_1 PF05105.12 AIM22921.1 - 1.2 9.3 8.4 5.5 7.2 0.1 3.0 2 1 1 3 3 3 0 Bacteriophage holin family ABC2_membrane_5 PF13346.6 AIM22921.1 - 1.9 8.0 13.4 3.1 7.3 13.4 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein SecE PF00584.20 AIM22921.1 - 6.3 6.8 16.3 4.6 7.2 0.3 3.5 3 0 0 3 3 3 0 SecE/Sec61-gamma subunits of protein translocation complex SPOR PF05036.13 AIM22922.1 - 5.6e-12 45.9 3.1 1.7e-11 44.4 0.3 2.1 2 0 0 2 2 2 1 Sporulation related domain TFIIA PF03153.13 AIM22922.1 - 2 8.3 9.6 2.6 8.0 9.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mur_ligase_M PF08245.12 AIM22923.1 - 7.6e-12 45.6 0.0 1.5e-11 44.6 0.0 1.5 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 AIM22923.1 - 5.4e-05 23.4 0.0 0.00016 21.8 0.0 1.8 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain Carboxyl_trans PF01039.22 AIM22924.1 - 2e-17 63.0 0.0 2.6e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Carboxyl transferase domain zf-ACC PF17848.1 AIM22924.1 - 8.5e-15 54.5 3.2 1.5e-14 53.7 3.2 1.4 1 0 0 1 1 1 1 Acetyl-coA carboxylase zinc finger domain zf-ribbon_3 PF13248.6 AIM22924.1 - 0.028 13.8 0.3 3.3 7.2 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain TFIIS_C PF01096.18 AIM22924.1 - 0.06 13.2 0.7 2.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) DZR PF12773.7 AIM22924.1 - 0.084 12.9 0.4 0.17 11.9 0.4 1.4 1 0 0 1 1 1 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 AIM22924.1 - 0.098 12.6 1.3 0.25 11.3 1.3 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Tmemb_55A PF09788.9 AIM22924.1 - 0.11 11.6 0.2 0.21 10.7 0.2 1.4 1 0 0 1 1 1 0 Transmembrane protein 55A zf-FPG_IleRS PF06827.14 AIM22924.1 - 0.22 11.4 1.0 0.47 10.4 1.0 1.5 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS Zn-ribbon_8 PF09723.10 AIM22924.1 - 0.24 11.5 2.4 0.29 11.3 1.2 1.8 2 0 0 2 2 2 0 Zinc ribbon domain Auto_anti-p27 PF06677.12 AIM22924.1 - 1.1 9.5 4.3 0.27 11.4 0.8 1.8 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) SNARE_assoc PF09335.11 AIM22925.1 - 2.2e-26 92.7 3.1 2.2e-26 92.7 3.1 1.9 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF456 PF04306.13 AIM22925.1 - 0.034 14.4 0.4 0.034 14.4 0.4 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF456) Doppel PF11466.8 AIM22925.1 - 0.13 11.9 2.2 1.6 8.5 0.3 2.9 3 0 0 3 3 3 0 Prion-like protein Doppel DUF2929 PF11151.8 AIM22925.1 - 1.4 9.3 8.4 3.6 7.9 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2929) PseudoU_synth_1 PF01416.20 AIM22926.1 - 1.3e-39 134.9 0.2 1.2e-27 96.5 0.0 2.1 2 0 0 2 2 2 2 tRNA pseudouridine synthase Semialdhyde_dhC PF02774.18 AIM22927.1 - 8.5e-37 127.0 0.1 1.9e-36 125.9 0.0 1.5 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 AIM22927.1 - 2.8e-25 89.1 0.0 5.2e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 AIM22927.1 - 0.067 13.9 0.0 0.15 12.8 0.0 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase 2-Hacid_dh_C PF02826.19 AIM22928.1 - 1.5e-30 105.8 0.0 4.1e-30 104.5 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF3410 PF11890.8 AIM22928.1 - 2.2e-30 104.3 0.0 3.6e-30 103.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3410) 2-Hacid_dh PF00389.30 AIM22928.1 - 5.6e-17 61.6 0.0 8.2e-17 61.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain DUF2867 PF11066.8 AIM22928.1 - 0.16 12.3 0.0 0.29 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2867) HTH_18 PF12833.7 AIM22929.1 - 3.5e-22 78.5 0.5 6.6e-22 77.6 0.5 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AIM22929.1 - 9e-11 41.6 0.0 9.7e-06 25.6 0.0 2.5 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Cupin_2 PF07883.11 AIM22929.1 - 1.4e-06 27.9 0.0 2.2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 AIM22929.1 - 2.9e-06 27.2 0.1 5.4e-06 26.3 0.1 1.4 1 1 0 1 1 1 1 AraC-like ligand binding domain EamA PF00892.20 AIM22930.1 - 4.8e-40 136.9 44.2 6.3e-20 71.8 11.4 2.0 2 0 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 AIM22930.1 - 0.0053 15.8 0.8 0.0053 15.8 0.8 2.1 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 AIM22930.1 - 0.43 9.9 14.2 1.6 8.0 7.0 2.3 2 1 0 2 2 2 0 Triose-phosphate Transporter family UAA PF08449.11 AIM22930.1 - 2.7 7.1 13.4 0.15 11.3 6.1 2.2 2 1 0 2 2 2 0 UAA transporter family 2CSK_N PF08521.10 AIM22931.1 - 4.1e-40 137.1 0.2 4.1e-40 137.1 0.2 1.7 2 0 0 2 2 2 1 Two-component sensor kinase N-terminal HATPase_c PF02518.26 AIM22931.1 - 9.8e-13 48.6 0.0 1.6e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AIM22931.1 - 1.7e-07 31.1 2.1 2.1e-07 30.9 0.5 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AIM22931.1 - 0.00029 21.1 0.1 0.00067 20.0 0.1 1.7 1 0 0 1 1 1 1 HAMP domain Response_reg PF00072.24 AIM22932.1 - 9.7e-27 93.4 0.0 1.5e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AIM22932.1 - 5.7e-18 64.8 0.1 1.5e-17 63.4 0.0 1.7 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal FleQ PF06490.11 AIM22932.1 - 0.019 15.3 0.0 0.03 14.7 0.0 1.3 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ OKR_DC_1_N PF03709.15 AIM22932.1 - 0.055 13.7 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain TctC PF03401.14 AIM22934.1 - 3.5e-19 68.9 0.0 4.5e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter family receptor Phosphonate-bd PF12974.7 AIM22934.1 - 0.072 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein TctB PF07331.11 AIM22935.1 - 8.1e-20 71.5 14.9 9.5e-20 71.3 14.9 1.0 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter TctB family MgtC PF02308.16 AIM22935.1 - 0.011 16.0 1.4 0.042 14.2 1.2 1.9 1 1 0 1 1 1 0 MgtC family TctA PF01970.16 AIM22936.1 - 1.8e-144 481.5 45.5 1.8e-144 481.5 45.5 1.3 2 0 0 2 2 2 1 Tripartite tricarboxylate transporter TctA family Hexapep PF00132.24 AIM22937.1 - 2.8e-13 49.0 2.6 5.7e-11 41.7 0.1 3.0 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AIM22937.1 - 1.8e-08 34.0 0.2 4e-08 32.9 0.2 1.6 1 0 0 1 1 1 1 Hexapeptide repeat of succinyl-transferase EamA PF00892.20 AIM22938.1 - 2.2e-32 112.1 44.7 4.5e-17 62.5 19.5 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 AIM22938.1 - 2.1e-07 30.6 9.3 8e-05 22.1 0.2 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family PUNUT PF16913.5 AIM22938.1 - 0.0011 18.2 1.7 0.0011 18.2 1.7 2.7 2 1 0 2 2 2 2 Purine nucleobase transmembrane transport TMEM234 PF10639.9 AIM22938.1 - 0.0028 17.7 0.8 0.0028 17.7 0.8 2.6 2 0 0 2 2 2 1 Putative transmembrane family 234 Aminotran_1_2 PF00155.21 AIM22939.1 - 3.8e-30 105.3 0.0 5.8e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II GntR PF00392.21 AIM22939.1 - 6.3e-18 64.2 1.8 7.9e-17 60.7 0.1 2.8 3 0 0 3 3 3 1 Bacterial regulatory proteins, gntR family Aminotran_MocR PF12897.7 AIM22939.1 - 7.6e-08 31.5 0.0 1.1e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase HTH_36 PF13730.6 AIM22939.1 - 0.011 15.6 0.0 0.046 13.7 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain Aminotran_5 PF00266.19 AIM22939.1 - 0.026 13.5 0.0 0.038 13.0 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-V Rrf2 PF02082.20 AIM22939.1 - 0.097 13.0 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator HTH_11 PF08279.12 AIM22939.1 - 0.15 12.0 0.0 0.54 10.3 0.0 1.9 1 0 0 1 1 1 0 HTH domain Redoxin PF08534.10 AIM22940.1 - 1.8e-13 50.5 0.0 2.4e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 AIM22940.1 - 3.7e-13 49.5 0.0 5e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin PF00085.20 AIM22940.1 - 9.6e-10 38.4 0.0 2.5e-07 30.6 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 AIM22940.1 - 8.7e-06 26.0 0.0 1.4e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 AIM22940.1 - 0.00023 21.6 0.0 0.00071 20.0 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain DUF5345 PF17280.2 AIM22940.1 - 0.028 14.4 0.0 0.053 13.5 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5345) Thioredoxin_7 PF13899.6 AIM22940.1 - 0.086 13.0 0.1 0.14 12.4 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_9 PF14595.6 AIM22940.1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Crystall_2 PF09076.10 AIM22940.1 - 0.19 11.7 0.0 0.33 10.9 0.0 1.3 1 0 0 1 1 1 0 Beta/Gamma crystallin Thioredoxin_4 PF13462.6 AIM22941.1 - 3.7e-25 89.0 0.2 7.3e-25 88.0 0.0 1.5 2 0 0 2 2 2 1 Thioredoxin DSBA PF01323.20 AIM22941.1 - 7.7e-24 84.5 1.7 1.4e-22 80.4 1.7 2.2 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 AIM22941.1 - 9.4e-14 51.8 1.2 6.4e-13 49.1 0.2 2.5 2 1 0 2 2 2 1 Thioredoxin-like domain ScsC_N PF18312.1 AIM22941.1 - 8.2e-12 44.7 2.3 1.7e-11 43.7 0.5 2.5 2 0 0 2 2 2 1 Copper resistance protein ScsC N-terminal domain Thioredoxin PF00085.20 AIM22941.1 - 1.4e-05 25.0 0.0 0.00018 21.5 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.6 AIM22941.1 - 2.7e-05 24.1 0.1 0.15 12.1 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin domain TraF PF13728.6 AIM22941.1 - 0.00047 20.1 2.0 0.088 12.6 1.0 2.9 2 1 0 2 2 2 2 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 AIM22941.1 - 0.0018 18.6 0.0 0.0094 16.3 0.1 2.2 2 1 0 2 2 2 1 Thioredoxin-like DUF2634 PF10934.8 AIM22941.1 - 0.2 11.8 0.0 0.9 9.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2634) DsbC PF11412.8 AIM22942.1 - 4.4e-16 59.0 0.0 1.1e-15 57.8 0.0 1.6 1 0 0 1 1 1 1 Disulphide bond corrector protein DsbC Thioredoxin_7 PF13899.6 AIM22942.1 - 6.4e-14 51.9 0.2 1.1e-13 51.1 0.2 1.4 1 0 0 1 1 1 1 Thioredoxin-like DsbD PF02683.15 AIM22942.1 - 2.1e-10 40.8 12.4 2.1e-10 40.8 12.4 1.5 2 0 0 2 2 2 1 Cytochrome C biogenesis protein transmembrane region Thioredox_DsbH PF03190.15 AIM22942.1 - 0.00041 20.3 0.1 0.0007 19.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin PF00085.20 AIM22942.1 - 0.012 15.6 0.3 0.02 14.9 0.3 1.3 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_2 PF13098.6 AIM22942.1 - 0.14 12.6 0.0 0.23 11.9 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain DUF1018 PF06252.12 AIM22944.1 - 0.00058 20.8 0.1 0.0023 18.9 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1018) CcmH PF03918.14 AIM22944.1 - 0.008 15.5 0.0 0.021 14.1 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C biogenesis protein HIF-1a_CTAD PF08778.10 AIM22944.1 - 0.12 12.0 0.0 0.12 12.0 0.0 2.7 3 0 0 3 3 3 0 HIF-1 alpha C terminal transactivation domain CHAD PF05235.14 AIM22944.1 - 4.8 7.1 8.2 78 3.1 8.3 2.2 1 1 0 1 1 1 0 CHAD domain Rhodanese PF00581.20 AIM22945.1 - 7.8e-11 42.4 0.0 1.2e-10 41.9 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Aminotran_1_2 PF00155.21 AIM22946.1 - 1.4e-20 73.8 0.0 2e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II GntR PF00392.21 AIM22946.1 - 5.1e-16 58.1 0.3 1.8e-15 56.3 0.2 2.1 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_Crp_2 PF13545.6 AIM22946.1 - 0.0077 16.2 0.1 0.027 14.5 0.1 2.0 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_41 PF14502.6 AIM22946.1 - 0.033 13.9 0.0 0.084 12.6 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain Exo_endo_phos PF03372.23 AIM22947.1 - 5.9e-08 32.5 0.1 1.3e-07 31.4 0.1 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family M20_dimer PF07687.14 AIM22948.1 - 2.7e-10 40.1 0.1 6.3e-10 38.9 0.1 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 AIM22948.1 - 7.7e-10 38.8 0.0 1.7e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 AIM22948.1 - 6.2e-09 35.3 0.0 5.3e-07 28.9 0.2 3.0 3 0 0 3 3 3 1 M42 glutamyl aminopeptidase Peptidase_M28 PF04389.17 AIM22948.1 - 0.015 15.0 0.0 0.08 12.6 0.1 1.9 2 1 0 2 2 2 0 Peptidase family M28 Fungal_KA1 PF16797.5 AIM22948.1 - 0.2 11.4 0.0 0.39 10.4 0.0 1.4 1 0 0 1 1 1 0 Fungal kinase associated-1 domain Peptidase_M66 PF10462.9 AIM22948.1 - 0.22 10.4 0.0 0.31 9.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase M66 CitMHS PF03600.16 AIM22949.1 - 1.5e-24 86.8 28.5 3.7e-24 85.4 27.9 1.8 1 1 1 2 2 2 1 Citrate transporter NhaB PF06450.12 AIM22949.1 - 2.9 6.6 13.6 0.85 8.4 0.2 2.5 2 1 1 3 3 3 0 Bacterial Na+/H+ antiporter B (NhaB) ApbE PF02424.15 AIM22950.1 - 2.9e-79 266.2 0.0 3.4e-79 266.0 0.0 1.0 1 0 0 1 1 1 1 ApbE family FlaE PF07559.14 AIM22951.1 - 0.085 13.4 0.0 0.092 13.3 0.0 1.1 1 0 0 1 1 1 0 Flagellar basal body protein FlaE ketoacyl-synt PF00109.26 AIM22952.1 - 6.1e-40 137.4 3.1 9.3e-40 136.8 3.1 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 AIM22952.1 - 1.5e-31 108.9 0.2 4.3e-31 107.4 0.2 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 AIM22952.1 - 0.00041 19.8 0.2 0.00081 18.8 0.2 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 AIM22952.1 - 0.00062 20.2 0.0 0.0011 19.4 0.0 1.5 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_30 PF05430.11 AIM22953.1 - 1.5e-47 160.5 0.0 3.5e-47 159.3 0.0 1.6 2 0 0 2 2 2 1 S-adenosyl-L-methionine-dependent methyltransferase DAO PF01266.24 AIM22953.1 - 9.8e-47 160.2 4.1 9.8e-47 160.2 4.1 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 AIM22953.1 - 0.0012 18.8 0.8 0.25 11.3 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 AIM22953.1 - 0.0069 15.6 0.0 0.018 14.3 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AIM22953.1 - 0.064 12.5 0.0 2.7 7.1 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase YfcL PF08891.11 AIM22954.1 - 7.4e-38 128.8 0.2 8.2e-38 128.6 0.2 1.0 1 0 0 1 1 1 1 YfcL protein IMS PF00817.20 AIM22954.1 - 0.098 12.6 0.1 0.13 12.3 0.1 1.1 1 0 0 1 1 1 0 impB/mucB/samB family EpmC PF04315.12 AIM22955.1 - 8.4e-80 266.2 0.0 9.6e-80 266.0 0.0 1.0 1 0 0 1 1 1 1 Elongation factor P hydroxylase Mg296 PF09644.10 AIM22955.1 - 0.16 12.1 0.1 0.32 11.1 0.1 1.4 1 0 0 1 1 1 0 Mg296 protein TauE PF01925.19 AIM22956.1 - 2.5e-45 155.0 29.3 3e-45 154.7 29.3 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE Peptidase_M74 PF03411.13 AIM22957.1 - 2e-95 318.9 0.0 2.3e-95 318.7 0.0 1.0 1 0 0 1 1 1 1 Penicillin-insensitive murein endopeptidase Chorismate_synt PF01264.21 AIM22958.1 - 4.6e-144 479.1 0.0 5.2e-144 478.9 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Nfu_N PF08712.11 AIM22958.1 - 0.0069 16.4 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal MTS PF05175.14 AIM22959.1 - 1.1e-16 60.8 0.0 2.8e-15 56.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 AIM22959.1 - 4.1e-07 30.6 0.0 8.1e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 AIM22959.1 - 1e-06 28.5 0.0 1.6e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.6 AIM22959.1 - 2.7e-06 27.3 0.0 3.8e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 AIM22959.1 - 2.8e-06 26.9 0.0 4.2e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.18 AIM22959.1 - 0.00028 20.6 0.9 0.00091 19.0 0.9 1.7 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Met_10 PF02475.16 AIM22959.1 - 0.00037 20.3 0.0 0.00068 19.4 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 AIM22959.1 - 0.00038 20.2 0.0 0.00064 19.4 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 N6_Mtase PF02384.16 AIM22959.1 - 0.0027 17.0 0.0 0.0044 16.3 0.0 1.3 1 0 0 1 1 1 1 N-6 DNA Methylase Ubie_methyltran PF01209.18 AIM22959.1 - 0.0045 16.4 0.0 0.0068 15.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 AIM22959.1 - 0.0082 15.5 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_18 PF12847.7 AIM22959.1 - 0.012 15.6 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 AIM22959.1 - 0.014 16.2 0.0 0.082 13.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 AIM22959.1 - 0.014 15.2 0.0 0.052 13.4 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Rsm22 PF09243.10 AIM22959.1 - 0.021 14.1 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_10 PF05971.12 AIM22959.1 - 0.059 12.7 0.0 0.089 12.1 0.0 1.2 1 0 0 1 1 1 0 RNA methyltransferase Methyltr_RsmB-F PF01189.17 AIM22959.1 - 0.089 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_16 PF10294.9 AIM22959.1 - 0.22 11.2 0.0 0.37 10.5 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase PrmC_N PF17827.1 AIM22959.1 - 0.23 12.1 0.3 1.7 9.2 0.2 2.4 2 1 0 2 2 2 0 PrmC N-terminal domain Smr PF01713.21 AIM22960.1 - 3.7e-18 65.6 0.3 4.7e-18 65.3 0.3 1.1 1 0 0 1 1 1 1 Smr domain His_Phos_1 PF00300.22 AIM22961.1 - 1.9e-08 34.2 0.4 2.4e-07 30.6 0.2 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) 3HCDH_N PF02737.18 AIM22962.1 - 1.4e-56 191.2 0.1 2.4e-56 190.5 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 AIM22962.1 - 3.7e-42 144.4 0.2 6.8e-42 143.5 0.2 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 AIM22962.1 - 3.7e-35 120.4 0.0 8.1e-25 87.3 0.0 2.7 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 AIM22962.1 - 3.9e-25 89.1 0.0 3.9e-25 89.1 0.0 1.4 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase Thiolase_N PF00108.23 AIM22963.1 - 7.3e-62 209.1 0.4 9.8e-62 208.7 0.4 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 AIM22963.1 - 5.8e-36 122.9 4.6 2.1e-35 121.1 1.5 2.9 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 AIM22963.1 - 0.00032 20.4 6.1 0.00079 19.1 2.3 3.0 4 0 0 4 4 4 1 Beta-ketoacyl synthase, N-terminal domain DUF406 PF04175.12 AIM22964.1 - 3.1e-40 136.6 2.2 3.4e-40 136.4 2.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF406) NODP PF07684.12 AIM22964.1 - 0.0057 16.8 0.1 0.0057 16.8 0.1 1.6 2 0 0 2 2 2 1 NOTCH protein Toluene_X PF03349.16 AIM22965.1 - 3.8e-142 473.9 8.6 4.4e-142 473.7 8.6 1.0 1 0 0 1 1 1 1 Outer membrane protein transport protein (OMPP1/FadL/TodX) YadA_anchor PF03895.15 AIM22965.1 - 0.015 15.4 12.0 0.16 12.1 0.0 5.0 4 1 0 5 5 5 0 YadA-like membrane anchor domain DUF2490 PF10677.9 AIM22965.1 - 0.03 14.3 4.2 0.86 9.5 0.0 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF2490) MlaA PF04333.13 AIM22966.1 - 7.1e-65 218.4 0.1 9e-65 218.0 0.1 1.0 1 0 0 1 1 1 1 MlaA lipoprotein TPR_19 PF14559.6 AIM22967.1 - 5.9e-10 39.5 1.1 4.1e-07 30.4 0.3 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 AIM22967.1 - 9e-08 32.3 0.9 0.0076 17.0 0.1 3.8 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 AIM22967.1 - 3.1e-05 23.7 0.0 0.022 14.9 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 AIM22967.1 - 0.0037 17.4 0.6 0.18 12.0 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 AIM22967.1 - 0.0041 17.3 0.0 0.011 15.9 0.0 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 AIM22967.1 - 0.024 15.3 0.5 1.3 9.7 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 AIM22967.1 - 0.14 12.5 0.1 19 5.9 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 AIM22967.1 - 0.18 12.1 0.0 1.2 9.5 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat CcmH PF03918.14 AIM22968.1 - 5.6e-57 191.1 0.1 6.7e-57 190.8 0.1 1.0 1 0 0 1 1 1 1 Cytochrome C biogenesis protein DUF3797 PF12677.7 AIM22968.1 - 0.034 14.0 0.0 0.059 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) CpXC PF14353.6 AIM22968.1 - 0.041 13.9 0.1 0.075 13.1 0.1 1.4 1 0 0 1 1 1 0 CpXC protein DUF4381 PF14316.6 AIM22968.1 - 0.084 13.1 0.5 1.1 9.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Redoxin PF08534.10 AIM22969.1 - 1.1e-24 86.9 0.0 1.3e-24 86.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 AIM22969.1 - 4.5e-15 55.7 0.0 5.6e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 AIM22969.1 - 1e-05 25.9 0.0 1.9e-05 25.1 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.20 AIM22969.1 - 0.00012 22.0 0.0 0.00021 21.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 AIM22969.1 - 0.001 19.3 0.0 0.0019 18.5 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.6 AIM22969.1 - 0.0029 17.8 0.0 0.006 16.7 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like DUF929 PF06053.11 AIM22969.1 - 0.26 10.5 0.0 0.34 10.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF929) CcmF_C PF16327.5 AIM22970.1 - 2.6e-131 437.7 5.9 2.6e-131 437.7 5.9 3.0 3 1 0 3 3 3 1 Cytochrome c-type biogenesis protein CcmF C-terminal Cytochrom_C_asm PF01578.20 AIM22970.1 - 3.8e-54 183.7 21.4 3.8e-54 183.7 21.4 3.3 5 0 0 5 5 5 1 Cytochrome C assembly protein ResB PF05140.14 AIM22970.1 - 0.14 10.9 0.3 2.6 6.7 0.2 2.3 2 0 0 2 2 2 0 ResB-like family PalH PF08733.10 AIM22970.1 - 2.1 7.3 8.4 0.24 10.4 3.5 1.9 2 0 0 2 2 2 0 PalH/RIM21 CcmE PF03100.15 AIM22971.1 - 7e-45 152.1 0.0 8.4e-45 151.9 0.0 1.1 1 0 0 1 1 1 1 CcmE DUF3951 PF13131.6 AIM22971.1 - 0.0034 17.5 0.0 0.011 15.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3951) CcmD PF04995.14 AIM22972.1 - 1.6e-17 63.3 7.3 1.6e-17 63.3 7.3 1.6 1 1 0 1 1 1 1 Heme exporter protein D (CcmD) MscS_TM PF12794.7 AIM22972.1 - 0.027 13.3 1.6 0.028 13.3 1.6 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Phage_Gp23 PF10669.9 AIM22972.1 - 0.046 14.0 0.0 0.052 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Cytochrom_C_asm PF01578.20 AIM22973.1 - 2.9e-33 115.4 17.9 2.9e-33 115.4 17.9 1.8 2 0 0 2 2 2 1 Cytochrome C assembly protein CcmB PF03379.13 AIM22974.1 - 1.3e-92 309.2 23.8 1.5e-92 309.0 23.8 1.0 1 0 0 1 1 1 1 CcmB protein ABC2_membrane PF01061.24 AIM22974.1 - 0.00029 20.3 5.4 0.00029 20.3 5.4 1.4 1 1 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 AIM22975.1 - 1.7e-27 96.6 0.0 2.4e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIM22975.1 - 5.5e-12 46.1 0.1 6.9e-05 22.8 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIM22975.1 - 4.1e-05 23.1 0.0 0.016 14.7 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 AIM22975.1 - 0.0034 17.1 0.2 0.015 15.0 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AIM22975.1 - 0.0046 17.4 0.1 0.0093 16.4 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AIM22975.1 - 0.015 15.2 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_27 PF13514.6 AIM22975.1 - 0.022 14.4 0.0 0.29 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF3584 PF12128.8 AIM22975.1 - 0.036 11.6 0.0 0.047 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_35 PF14516.6 AIM22975.1 - 0.058 12.2 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain NACHT PF05729.12 AIM22975.1 - 0.066 13.1 0.1 0.37 10.7 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.6 AIM22975.1 - 0.1 13.1 0.0 0.15 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AIM22975.1 - 0.11 12.3 0.0 0.39 10.5 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain Form_Nir_trans PF01226.17 AIM22976.1 - 9.9e-42 142.9 12.1 1.1e-41 142.7 12.1 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter FUSC-like PF12805.7 AIM22977.1 - 0.034 13.2 1.0 0.038 13.1 1.0 1.0 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS HTH_18 PF12833.7 AIM22978.1 - 1.8e-19 69.8 0.2 2.9e-19 69.1 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AIM22978.1 - 7.2e-15 54.6 0.3 1.4e-07 31.5 0.1 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Cass2 PF14526.6 AIM22978.1 - 2.3e-08 34.3 1.3 4.8e-08 33.3 0.3 2.0 1 1 0 2 2 2 1 Integron-associated effector binding protein GyrI-like PF06445.15 AIM22978.1 - 7.6e-05 23.1 0.0 0.00012 22.4 0.0 1.4 1 0 0 1 1 1 1 GyrI-like small molecule binding domain Bac_DNA_binding PF00216.21 AIM22980.1 - 0.023 14.9 0.5 0.046 13.9 0.5 1.5 1 0 0 1 1 1 0 Bacterial DNA-binding protein UvrD_C PF13361.6 AIM22980.1 - 0.028 13.8 0.0 0.028 13.8 0.0 1.1 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain APC_N_CC PF16689.5 AIM22980.1 - 0.19 11.8 0.8 0.38 10.9 0.8 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain DUF3792 PF12670.7 AIM22980.1 - 0.7 10.1 17.6 0.31 11.2 13.8 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3792) PAS_4 PF08448.10 AIM22981.1 - 1e-22 80.4 1.5 4.1e-08 33.5 0.2 3.5 3 0 0 3 3 3 3 PAS fold PAS_9 PF13426.7 AIM22981.1 - 1e-21 77.2 0.0 3.9e-06 27.1 0.0 3.7 3 1 0 3 3 3 3 PAS domain PAS PF00989.25 AIM22981.1 - 1.8e-19 69.8 0.0 2.1e-05 24.5 0.0 3.4 3 0 0 3 3 3 3 PAS fold PAS_8 PF13188.7 AIM22981.1 - 2.3e-19 68.9 0.2 4.6e-06 26.5 0.0 3.5 3 0 0 3 3 3 3 PAS domain GerE PF00196.19 AIM22981.1 - 2.3e-17 62.3 0.0 4.8e-17 61.2 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family PAS_3 PF08447.12 AIM22981.1 - 8.8e-06 25.9 0.0 0.14 12.4 0.0 2.9 2 0 0 2 2 2 2 PAS fold PAS_7 PF12860.7 AIM22981.1 - 0.00011 22.4 0.0 2 8.6 0.0 3.9 3 2 0 3 3 3 2 PAS fold Sigma70_r4_2 PF08281.12 AIM22981.1 - 0.0011 18.6 0.1 0.0054 16.4 0.0 2.1 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AIM22981.1 - 0.0061 16.1 0.0 0.018 14.6 0.0 1.9 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_40 PF14493.6 AIM22981.1 - 0.056 13.9 0.0 0.24 11.9 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.6 AIM22981.1 - 0.11 12.3 0.0 0.41 10.5 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain CsbD PF05532.12 AIM22982.1 - 1.6e-13 50.3 4.3 2.1e-13 49.9 4.3 1.1 1 0 0 1 1 1 1 CsbD-like DUF883 PF05957.13 AIM22982.1 - 8.8e-08 32.6 1.7 2.4e-07 31.3 1.7 1.7 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF883) Lipoprotein_2 PF00921.17 AIM22982.1 - 0.059 12.9 0.7 0.06 12.9 0.7 1.1 1 0 0 1 1 1 0 Borrelia lipoprotein LysR_substrate PF03466.20 AIM22983.1 - 5.9e-26 91.1 0.0 1e-25 90.4 0.0 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM22983.1 - 3e-20 71.9 0.3 5.8e-20 71.0 0.3 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AIM22983.1 - 0.032 14.0 0.3 0.072 12.9 0.3 1.6 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_24 PF13412.6 AIM22983.1 - 0.044 13.4 0.0 0.092 12.3 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 AIM22983.1 - 0.16 11.9 0.2 0.41 10.6 0.0 1.8 2 0 0 2 2 2 0 MarR family EamA PF00892.20 AIM22985.1 - 2.2e-29 102.4 29.2 8.9e-18 64.8 17.2 2.0 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 AIM22985.1 - 0.044 13.1 10.6 1.3 8.3 5.4 2.2 2 0 0 2 2 2 0 Triose-phosphate Transporter family DUF2070 PF09843.9 AIM22985.1 - 0.11 10.8 22.3 0.018 13.4 14.2 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) Autotransporter PF03797.19 AIM22987.1 - 1.7e-06 27.9 10.6 1.7e-06 27.9 10.6 2.1 2 1 0 2 2 2 1 Autotransporter beta-domain Attachment_P66 PF11263.8 AIM22987.1 - 0.029 13.6 0.7 0.086 12.1 0.4 1.9 2 0 0 2 2 2 0 Borrelia burgdorferi attachment protein P66 SLT_2 PF13406.6 AIM22988.1 - 8e-93 310.8 0.0 9.3e-93 310.6 0.0 1.0 1 0 0 1 1 1 1 Transglycosylase SLT domain Glucosaminidase PF01832.20 AIM22988.1 - 0.023 15.2 0.0 0.04 14.4 0.0 1.5 1 0 0 1 1 1 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase SLT PF01464.20 AIM22988.1 - 0.032 13.9 0.0 0.16 11.6 0.0 2.0 1 1 0 1 1 1 0 Transglycosylase SLT domain DUF805 PF05656.14 AIM22989.1 - 2.8e-08 34.1 2.1 3.6e-08 33.8 2.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF805) 7TMR-DISM_7TM PF07695.11 AIM22989.1 - 0.0039 17.1 12.6 0.0052 16.7 6.3 2.0 1 1 1 2 2 2 2 7TM diverse intracellular signalling UPF0182 PF03699.13 AIM22989.1 - 0.09 10.9 0.3 0.1 10.7 0.3 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) DUF1449 PF07290.11 AIM22989.1 - 0.27 10.8 3.5 0.43 10.2 3.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1449) DUF202 PF02656.15 AIM22989.1 - 2.4 8.7 6.1 0.91 10.0 2.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF202) HicB-like_2 PF15970.5 AIM22990.1 - 1.9e-22 79.2 0.0 2.5e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicB_lk_antitox PF15919.5 AIM22990.1 - 0.15 12.2 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 HicB_like antitoxin of bacterial toxin-antitoxin system Ni_hydr_CYTB PF01292.20 AIM22991.1 - 2e-23 83.0 12.3 2.3e-23 82.8 12.3 1.0 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 TilS PF09179.11 AIM22991.1 - 0.1 13.1 0.0 0.26 11.8 0.0 1.7 1 0 0 1 1 1 0 TilS substrate binding domain Oxidored_q3 PF00499.20 AIM22991.1 - 0.19 11.4 3.8 0.1 12.3 2.0 1.4 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Ndc1_Nup PF09531.10 AIM22991.1 - 0.78 8.4 4.4 1 8.0 4.4 1.3 1 1 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4293 PF14126.6 AIM22991.1 - 1.2 9.4 5.6 0.14 12.4 0.8 1.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4293) Aminotran_1_2 PF00155.21 AIM22992.1 - 7.4e-58 196.4 0.0 8.3e-58 196.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 AIM22992.1 - 0.021 13.7 0.0 0.35 9.7 0.0 2.2 1 1 0 1 1 1 0 Allinase Cys_Met_Meta_PP PF01053.20 AIM22992.1 - 0.091 11.3 0.0 0.13 10.7 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme PM0188 PF11477.8 AIM22992.1 - 0.24 10.5 0.0 0.35 10.0 0.0 1.1 1 0 0 1 1 1 0 Sialyltransferase PMO188 Acetyltransf_3 PF13302.7 AIM22993.1 - 2.5e-26 93.0 0.0 2.9e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AIM22993.1 - 8e-11 42.2 0.0 1e-10 41.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 AIM22993.1 - 4.4e-08 33.4 0.0 5.2e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 AIM22993.1 - 0.016 14.9 0.0 0.056 13.1 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 AIM22993.1 - 0.019 15.0 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein DUF1479 PF07350.12 AIM22994.1 - 5.9e-140 466.7 0.0 6.8e-140 466.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 AIM22994.1 - 0.00022 21.6 0.0 0.0018 18.6 0.0 2.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) LytTR PF04397.15 AIM22995.1 - 1.5e-30 105.3 0.2 3.3e-30 104.2 0.2 1.6 1 0 0 1 1 1 1 LytTr DNA-binding domain Response_reg PF00072.24 AIM22995.1 - 1.3e-23 83.3 0.2 2e-23 82.7 0.2 1.3 1 0 0 1 1 1 1 Response regulator receiver domain DUF2502 PF10697.9 AIM22996.1 - 6.8e-14 52.0 13.8 6.8e-14 52.0 13.8 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF2502) Defensin_propep PF00879.18 AIM22996.1 - 0.91 9.8 3.4 1.3 9.4 3.4 1.1 1 0 0 1 1 1 0 Defensin propeptide MFS_1 PF07690.16 AIM22997.1 - 2e-31 109.2 53.1 1.9e-17 63.2 21.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AIM22997.1 - 0.0022 16.9 35.8 0.01 14.7 3.3 3.4 2 1 1 3 3 3 2 Sugar (and other) transporter Glucokinase PF02685.16 AIM22998.1 - 1.2e-124 415.4 0.0 1.4e-124 415.2 0.0 1.0 1 0 0 1 1 1 1 Glucokinase PaaX_C PF08223.11 AIM22998.1 - 0.02 15.2 0.0 0.033 14.5 0.0 1.3 1 0 0 1 1 1 0 PaaX-like protein C-terminal domain Voltage_CLC PF00654.20 AIM22999.1 - 6.7e-24 84.8 34.8 6.7e-24 84.8 34.8 1.7 1 1 0 1 1 1 1 Voltage gated chloride channel Hol_Tox PF16935.5 AIM22999.1 - 0.059 13.4 1.1 0.059 13.4 1.1 2.0 2 0 0 2 2 2 0 Putative Holin-like Toxin (Hol-Tox) Asp_Glu_race PF01177.22 AIM23000.1 - 8.1e-60 202.4 0.1 9.1e-60 202.3 0.1 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Peripla_BP_1 PF00532.21 AIM23000.1 - 0.00067 19.2 0.2 0.047 13.1 0.1 2.2 2 0 0 2 2 2 2 Periplasmic binding proteins and sugar binding domain of LacI family PA PF02225.22 AIM23000.1 - 0.016 15.2 0.4 0.18 11.8 0.2 2.1 2 0 0 2 2 2 0 PA domain Pantoate_transf PF02548.15 AIM23000.1 - 0.032 13.6 0.3 0.053 12.9 0.3 1.3 1 0 0 1 1 1 0 Ketopantoate hydroxymethyltransferase HisG_C PF08029.11 AIM23000.1 - 0.09 12.9 0.2 3.9 7.7 0.0 2.5 2 0 0 2 2 2 0 HisG, C-terminal domain BTP PF05232.12 AIM23001.1 - 5.9e-51 170.4 14.5 5.3e-26 90.5 3.0 2.0 2 0 0 2 2 2 2 Chlorhexidine efflux transporter LysR_substrate PF03466.20 AIM23002.1 - 4.6e-22 78.4 1.3 4.6e-22 78.4 1.3 1.8 2 1 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AIM23002.1 - 1.8e-17 63.0 3.8 3.1e-17 62.3 3.0 1.9 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family TPP_enzyme_N PF02776.18 AIM23003.1 - 1.8e-35 122.1 1.0 1.1e-34 119.6 0.5 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 AIM23003.1 - 4.2e-22 78.6 0.0 3.6e-21 75.5 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 AIM23003.1 - 5.3e-17 61.8 0.1 2.1e-16 59.9 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain SEFIR PF08357.11 AIM23003.1 - 0.11 12.8 0.0 0.62 10.3 0.0 2.0 2 0 0 2 2 2 0 SEFIR domain Aldo_ket_red PF00248.21 AIM23004.1 - 3.1e-69 233.4 0.0 3.5e-69 233.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AP_endonuc_2 PF01261.24 AIM23004.1 - 0.051 13.0 0.0 0.14 11.6 0.0 1.8 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel ANTAR PF03861.14 AIM23004.1 - 5.2 7.0 5.9 49 3.9 1.0 3.3 3 0 0 3 3 3 0 ANTAR domain DUF2502 PF10697.9 AIM23005.1 - 1.9e-30 105.0 69.8 8.2e-26 90.2 33.9 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF2502) Nramp PF01566.18 AIM23006.1 - 7.9e-121 403.4 30.6 9.4e-121 403.1 30.6 1.1 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Nucleos_tra2_C PF07662.13 AIM23007.1 - 8.6e-63 211.9 12.6 8.6e-63 211.9 12.6 2.7 3 1 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 AIM23007.1 - 7.8e-18 64.9 5.3 7.8e-18 64.9 5.3 4.2 3 1 1 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 AIM23007.1 - 1.3e-07 31.9 5.3 1.3e-07 31.9 5.3 4.2 2 1 2 4 4 4 1 Nucleoside recognition Fimbrial PF00419.20 AIM23009.1 - 1.5e-17 64.2 9.9 1.9e-17 63.9 9.9 1.1 1 0 0 1 1 1 1 Fimbrial protein FimA PF16970.5 AIM23009.1 - 8.3e-05 22.8 11.2 0.0012 19.1 6.4 2.4 2 1 0 2 2 2 1 Type-1 fimbrial protein, A NIR_SIR PF01077.22 AIM23009.1 - 0.0032 17.0 0.0 0.0047 16.5 0.0 1.2 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain PapD_N PF00345.20 AIM23010.1 - 2.8e-42 143.6 0.6 4.4e-42 142.9 0.6 1.3 1 0 0 1 1 1 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain PapD_C PF02753.17 AIM23010.1 - 3.4e-18 65.7 0.0 8.2e-18 64.5 0.0 1.7 1 0 0 1 1 1 1 Pili assembly chaperone PapD, C-terminal domain Usher PF00577.20 AIM23011.1 - 1e-181 605.6 25.2 1.2e-181 605.4 25.2 1.0 1 0 0 1 1 1 1 Outer membrane usher protein PapC_N PF13954.6 AIM23011.1 - 1.7e-43 148.1 0.1 4e-43 146.9 0.1 1.7 1 0 0 1 1 1 1 PapC N-terminal domain Fimbrial PF00419.20 AIM23012.1 - 3.8e-10 40.2 0.3 9.1e-10 39.0 0.2 1.6 2 0 0 2 2 2 1 Fimbrial protein Form_Nir_trans PF01226.17 AIM23013.1 - 3.4e-74 249.1 28.6 3.9e-74 249.0 28.6 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter tRNA-synt_1c PF00749.21 AIM23014.1 - 1.1e-116 389.2 0.0 1.3e-116 388.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain IL10 PF00726.17 AIM23014.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Interleukin 10 Acetyltransf_10 PF13673.7 AIM23015.1 - 2.7e-11 43.5 0.0 3.5e-11 43.1 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AIM23015.1 - 4.3e-10 39.9 0.0 4.8e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AIM23015.1 - 1.3e-06 28.7 0.0 1.7e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AIM23015.1 - 0.00057 20.0 0.1 0.00081 19.5 0.1 1.2 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 AIM23015.1 - 0.0061 17.2 0.1 0.0073 17.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AIM23015.1 - 0.021 14.9 0.1 0.033 14.3 0.1 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Peripla_BP_2 PF01497.18 AIM23016.1 - 3.5e-31 108.6 0.4 4.6e-31 108.2 0.4 1.1 1 0 0 1 1 1 1 Periplasmic binding protein HGD-D PF06050.13 AIM23016.1 - 0.17 11.7 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component FecCD PF01032.18 AIM23017.1 - 7e-87 291.3 37.9 8.3e-87 291.1 37.9 1.0 1 0 0 1 1 1 1 FecCD transport family DUF1118 PF06549.12 AIM23017.1 - 4.2 7.7 7.8 0.53 10.6 2.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1118) FecCD PF01032.18 AIM23018.1 - 2.8e-82 276.2 39.8 3.5e-82 275.9 39.8 1.0 1 0 0 1 1 1 1 FecCD transport family ABC_tran PF00005.27 AIM23019.1 - 1.3e-30 106.7 0.0 1.9e-30 106.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIM23019.1 - 8.2e-13 48.8 0.4 5.3e-06 26.5 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIM23019.1 - 3.4e-10 39.7 0.0 1.5e-07 31.1 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 AIM23019.1 - 2.8e-08 33.9 0.0 6.1e-06 26.2 0.0 2.1 1 1 0 2 2 2 1 AAA ATPase domain ABC_ATPase PF09818.9 AIM23019.1 - 5.3e-08 32.1 0.0 0.00078 18.4 0.0 3.0 2 1 0 2 2 2 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 AIM23019.1 - 5.3e-06 26.9 0.5 3.6e-05 24.2 0.5 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 AIM23019.1 - 1.2e-05 25.9 0.0 1.8e-05 25.4 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AIM23019.1 - 7.3e-05 22.4 0.0 0.00015 21.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_27 PF13514.6 AIM23019.1 - 0.00034 20.3 0.0 0.0007 19.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 AIM23019.1 - 0.0038 16.6 0.0 0.0093 15.4 0.0 1.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 AIM23019.1 - 0.006 16.3 0.0 0.012 15.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 AIM23019.1 - 0.0065 16.5 0.0 0.015 15.4 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 AIM23019.1 - 0.0072 16.5 0.1 0.027 14.6 0.1 2.0 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.6 AIM23019.1 - 0.009 16.3 0.2 0.03 14.6 0.2 1.9 1 1 0 1 1 1 1 AAA domain Adeno_IVa2 PF02456.15 AIM23019.1 - 0.013 14.4 0.0 0.031 13.1 0.0 1.7 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_14 PF13173.6 AIM23019.1 - 0.013 15.5 0.0 0.075 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF2813 PF11398.8 AIM23019.1 - 0.024 13.9 0.1 0.063 12.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) AAA_25 PF13481.6 AIM23019.1 - 0.025 14.1 0.1 0.093 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 AIM23019.1 - 0.036 14.0 0.1 1 9.3 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.6 AIM23019.1 - 0.04 14.4 0.1 0.26 11.8 0.0 2.1 1 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 AIM23019.1 - 0.045 13.6 0.0 0.13 12.2 0.0 1.6 1 1 1 2 2 2 0 RsgA GTPase ATPase_2 PF01637.18 AIM23019.1 - 0.056 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 AIM23019.1 - 0.068 13.6 0.1 0.28 11.6 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 AIM23019.1 - 0.087 13.1 0.2 0.18 12.0 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 AIM23019.1 - 0.1 12.6 0.1 2.1 8.3 0.0 2.5 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 AIM23019.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain MutS_V PF00488.21 AIM23019.1 - 0.17 11.9 0.0 0.38 10.8 0.0 1.5 1 0 0 1 1 1 0 MutS domain V RNA_helicase PF00910.22 AIM23019.1 - 0.21 12.0 0.0 0.48 10.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase SBP_bac_5 PF00496.22 AIM23020.1 - 9.7e-97 324.3 3.0 1.2e-96 324.0 3.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle TPP_enzyme_N PF02776.18 AIM23021.1 - 1.1e-50 171.6 3.9 3.7e-47 160.1 1.2 2.9 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 AIM23021.1 - 6.1e-40 136.5 0.1 1.3e-39 135.5 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 AIM23021.1 - 2e-29 102.1 0.0 4e-29 101.1 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain CO_dh PF02552.16 AIM23021.1 - 0.00079 19.2 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit AAL_decarboxy PF03306.13 AIM23022.1 - 2e-87 292.2 0.0 2.3e-87 291.9 0.0 1.0 1 0 0 1 1 1 1 Alpha-acetolactate decarboxylase DUF3748 PF12566.8 AIM23022.1 - 0.032 14.2 0.1 0.059 13.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3748) LysR_substrate PF03466.20 AIM23023.1 - 6.8e-40 136.7 3.3 9.2e-40 136.2 3.3 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM23023.1 - 8e-20 70.5 0.8 3.6e-19 68.5 0.2 2.3 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family EutC PF05985.11 AIM23024.1 - 2.9e-91 304.9 0.0 3.3e-91 304.7 0.0 1.0 1 0 0 1 1 1 1 Ethanolamine ammonia-lyase light chain (EutC) EutB PF06751.11 AIM23025.1 - 2e-222 738.7 0.0 2.2e-222 738.5 0.0 1.0 1 0 0 1 1 1 1 Ethanolamine ammonia lyase large subunit (EutB) NTP_transf_6 PF06042.11 AIM23026.1 - 4.3e-58 195.7 0.0 5.1e-58 195.4 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyltransferase FlxA PF14282.6 AIM23027.1 - 8e-18 64.3 19.6 8e-18 64.3 19.6 1.3 1 1 0 1 1 1 1 FlxA-like protein NPV_P10 PF05531.12 AIM23027.1 - 0.0018 18.7 3.8 0.0035 17.8 3.8 1.4 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein Fmp27_WPPW PF10359.9 AIM23027.1 - 0.0028 16.6 7.7 0.0035 16.3 7.7 1.0 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Mer2 PF09074.10 AIM23027.1 - 0.018 14.9 4.8 0.025 14.4 4.8 1.1 1 0 0 1 1 1 0 Mer2 Dynamitin PF04912.14 AIM23027.1 - 0.027 13.8 8.7 0.033 13.5 8.7 1.0 1 0 0 1 1 1 0 Dynamitin FAM76 PF16046.5 AIM23027.1 - 0.042 13.2 5.8 0.052 12.9 5.8 1.1 1 0 0 1 1 1 0 FAM76 protein MRP-S27 PF10037.9 AIM23027.1 - 0.077 11.8 5.8 0.075 11.9 5.8 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 BLYB PF05289.11 AIM23027.1 - 0.11 12.7 3.7 0.18 12.0 3.7 1.3 1 0 0 1 1 1 0 Borrelia hemolysin accessory protein Cob_adeno_trans PF01923.18 AIM23027.1 - 0.2 11.8 3.3 0.26 11.4 3.3 1.2 1 0 0 1 1 1 0 Cobalamin adenosyltransferase Hormone_1 PF00103.20 AIM23027.1 - 0.24 11.1 2.6 0.31 10.8 2.6 1.2 1 0 0 1 1 1 0 Somatotropin hormone family DUF5320 PF17253.2 AIM23027.1 - 0.29 12.2 10.0 2.9 9.0 3.0 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5320) MerR-DNA-bind PF09278.11 AIM23027.1 - 0.3 11.7 10.9 0.92 10.1 0.9 2.3 1 1 1 2 2 2 0 MerR, DNA binding Allexi_40kDa PF05549.11 AIM23027.1 - 0.37 10.3 3.2 0.5 9.8 3.2 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein HAUS6_N PF14661.6 AIM23027.1 - 0.4 10.2 8.6 0.49 9.9 8.6 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Qua1 PF16274.5 AIM23027.1 - 0.43 10.4 5.1 0.26 11.2 2.7 1.9 1 1 1 2 2 2 0 Qua1 domain PCRF PF03462.18 AIM23027.1 - 0.89 9.4 6.7 1.2 9.0 6.7 1.1 1 0 0 1 1 1 0 PCRF domain GTP-bdg_M PF16360.5 AIM23027.1 - 0.92 10.1 11.7 3.8 8.2 5.1 2.2 1 1 1 2 2 2 0 GTP-binding GTPase Middle Region DUF3375 PF11855.8 AIM23027.1 - 0.96 8.3 14.3 2.7 6.8 7.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3375) YabA PF06156.13 AIM23027.1 - 1 10.0 7.1 1.7 9.3 7.1 1.4 1 0 0 1 1 1 0 Initiation control protein YabA Swi5 PF07061.11 AIM23027.1 - 1.1 9.4 13.0 0.27 11.3 3.4 2.2 1 1 1 2 2 2 0 Swi5 V_ATPase_I PF01496.19 AIM23027.1 - 1.2 7.0 7.1 1.4 6.8 7.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family T2SSM PF04612.12 AIM23027.1 - 1.4 9.0 8.1 2.4 8.2 8.1 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M DivIC PF04977.15 AIM23027.1 - 1.4 8.7 17.3 9e+03 -3.5 17.3 2.4 1 1 0 1 1 0 0 Septum formation initiator Uso1_p115_C PF04871.13 AIM23027.1 - 1.4 9.3 15.9 2 8.8 15.9 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF1192 PF06698.11 AIM23027.1 - 1.5 9.0 11.6 0.27 11.3 6.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) APG6_N PF17675.1 AIM23027.1 - 3.2 8.3 18.0 9.8 6.7 18.0 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region GIT_CC PF16559.5 AIM23027.1 - 4.2 7.3 11.4 3.5 7.6 4.3 2.3 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4140 PF13600.6 AIM23027.1 - 5 7.6 12.9 2.1 8.9 1.5 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Spc24 PF08286.11 AIM23027.1 - 5.6 7.3 13.2 16 5.8 6.8 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 LysR_substrate PF03466.20 AIM23028.1 - 3.2e-44 150.8 7.9 3.2e-44 150.8 7.9 1.5 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AIM23028.1 - 1e-23 83.0 1.1 1e-23 83.0 1.1 2.9 3 0 0 3 3 3 1 Bacterial regulatory helix-turn-helix protein, lysR family PBP_like PF12727.7 AIM23028.1 - 0.006 15.7 0.0 1.3 8.1 0.0 2.5 1 1 1 2 2 2 2 PBP superfamily domain MarR_2 PF12802.7 AIM23028.1 - 0.027 14.4 2.9 0.029 14.2 0.0 2.5 4 0 0 4 4 4 0 MarR family DUF4438 PF14505.6 AIM23028.1 - 0.12 11.3 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4438) SBF_like PF13593.6 AIM23029.1 - 1.8e-98 329.7 20.5 2e-98 329.5 20.5 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 AIM23029.1 - 2.6e-14 53.4 6.0 2.6e-14 53.4 6.0 1.8 2 1 0 2 2 2 1 Sodium Bile acid symporter family QSregVF_b PF12843.7 AIM23030.1 - 5.4e-31 106.3 0.8 5.9e-31 106.1 0.8 1.0 1 0 0 1 1 1 1 Putative quorum-sensing-regulated virulence factor DNA_ligase_aden PF01653.18 AIM23031.1 - 2.4e-138 460.6 0.0 3.6e-138 460.0 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.16 AIM23031.1 - 2.5e-36 123.4 3.5 6.4e-36 122.1 3.5 1.7 1 0 0 1 1 1 1 NAD-dependent DNA ligase OB-fold domain HHH_2 PF12826.7 AIM23031.1 - 5.2e-22 77.7 0.1 2.1e-20 72.6 0.3 2.7 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 AIM23031.1 - 2.1e-14 53.9 0.3 2.1e-06 28.3 0.0 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix domain BRCT PF00533.26 AIM23031.1 - 1.5e-13 50.9 0.0 3.1e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DNA_ligase_ZBD PF03119.16 AIM23031.1 - 1.7e-11 43.9 4.8 4.6e-11 42.5 4.8 1.8 1 0 0 1 1 1 1 NAD-dependent DNA ligase C4 zinc finger domain PTCB-BRCT PF12738.7 AIM23031.1 - 1.8e-06 27.8 0.0 4e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain HHH PF00633.23 AIM23031.1 - 0.00044 20.0 0.1 0.0032 17.2 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix motif 5_3_exonuc PF01367.20 AIM23031.1 - 0.00059 20.4 0.1 0.02 15.5 0.0 2.7 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold zf-NADH-PPase PF09297.11 AIM23031.1 - 0.33 10.6 2.3 0.6 9.8 2.3 1.4 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain ZipA_C PF04354.13 AIM23032.1 - 2.4e-49 166.5 0.2 3.1e-49 166.1 0.2 1.1 1 0 0 1 1 1 1 ZipA, C-terminal FtsZ-binding domain EI24 PF07264.11 AIM23033.1 - 1.8e-44 152.1 17.1 2e-44 151.9 17.1 1.0 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) PALP PF00291.25 AIM23034.1 - 9.7e-70 235.3 0.6 1.1e-69 235.1 0.6 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.26 AIM23034.1 - 0.024 14.6 0.4 0.43 10.6 0.4 2.3 1 1 0 1 1 1 0 Zinc-binding dehydrogenase DFP PF04127.15 AIM23034.1 - 0.063 13.1 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein PTS-HPr PF00381.19 AIM23035.1 - 9.6e-29 99.5 0.2 1e-28 99.3 0.2 1.0 1 0 0 1 1 1 1 PTS HPr component phosphorylation site MG1 PF17790.1 AIM23035.1 - 0.01 16.2 0.0 0.016 15.7 0.0 1.4 1 1 0 1 1 1 0 Macroglobulin domain MG1 PEP-utilizers_C PF02896.18 AIM23036.1 - 9.7e-126 418.8 0.1 1.3e-125 418.4 0.1 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilisers_N PF05524.13 AIM23036.1 - 3.3e-29 101.4 4.1 3.3e-29 101.4 4.1 2.7 4 0 0 4 4 4 1 PEP-utilising enzyme, N-terminal PEP-utilizers PF00391.23 AIM23036.1 - 6.5e-23 80.2 0.1 2.4e-22 78.4 0.1 2.1 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain HpcH_HpaI PF03328.14 AIM23036.1 - 0.016 14.4 0.1 0.033 13.3 0.1 1.5 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family HalX PF08663.10 AIM23036.1 - 0.069 13.5 2.6 0.2 12.0 0.1 2.6 2 0 0 2 2 2 0 HalX domain MutS_III PF05192.18 AIM23036.1 - 0.13 12.5 1.4 0.43 10.8 0.0 2.2 2 1 0 2 2 2 0 MutS domain III PTS_EIIA_1 PF00358.20 AIM23037.1 - 1e-48 164.3 1.6 1.2e-48 164.0 1.6 1.1 1 0 0 1 1 1 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Biotin_lipoyl_2 PF13533.6 AIM23037.1 - 0.0027 17.5 0.2 0.044 13.6 0.0 2.6 3 0 0 3 3 3 1 Biotin-lipoyl like RnfC_N PF13375.6 AIM23037.1 - 0.02 14.8 0.4 2.8 8.0 0.0 3.0 2 1 1 3 3 3 0 RnfC Barrel sandwich hybrid domain Peptidase_M23 PF01551.22 AIM23037.1 - 0.099 12.9 0.7 1.5 9.1 0.3 2.5 1 1 1 2 2 2 0 Peptidase family M23 HATPase_c PF02518.26 AIM23038.1 - 3.1e-18 66.3 0.0 5.9e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 AIM23038.1 - 3.4e-11 43.3 3.0 6.9e-11 42.4 1.0 2.5 2 0 0 2 2 2 1 HAMP domain HisKA PF00512.25 AIM23038.1 - 6.8e-11 42.1 4.6 7.9e-10 38.6 2.4 2.7 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 AIM23038.1 - 5.4e-05 23.1 0.0 0.00011 22.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 AIM23038.1 - 0.0048 16.7 0.0 0.0082 16.0 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AIM23039.1 - 4.8e-21 75.0 0.0 6.8e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AIM23039.1 - 1.1e-20 73.4 0.5 4.9e-20 71.4 0.0 2.0 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal PALP PF00291.25 AIM23040.1 - 1.1e-66 225.3 1.4 1.7e-66 224.7 1.4 1.3 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ABC_tran PF00005.27 AIM23041.1 - 2.1e-36 125.5 0.0 3.2e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIM23041.1 - 2.5e-09 37.4 2.1 0.0012 18.7 0.3 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIM23041.1 - 2e-08 34.0 0.1 6.5e-08 32.3 0.1 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AIM23041.1 - 7.2e-05 23.2 0.3 0.0005 20.5 0.3 2.1 1 1 0 1 1 1 1 AAA ATPase domain TOBE_3 PF12857.7 AIM23041.1 - 0.00031 20.6 0.0 0.00083 19.2 0.0 1.7 1 0 0 1 1 1 1 TOBE-like domain NACHT PF05729.12 AIM23041.1 - 0.0012 18.8 1.2 0.034 14.1 0.2 2.4 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.6 AIM23041.1 - 0.0016 18.2 0.1 0.31 10.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 AIM23041.1 - 0.0023 17.9 0.2 0.027 14.4 0.0 2.1 2 0 0 2 2 2 1 NTPase AAA PF00004.29 AIM23041.1 - 0.0024 18.3 0.1 0.024 15.1 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 AIM23041.1 - 0.0024 17.5 0.1 0.0056 16.4 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 AIM23041.1 - 0.0046 17.2 0.1 0.057 13.6 0.1 2.4 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 AIM23041.1 - 0.0051 17.1 0.8 0.043 14.1 0.8 2.1 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AIM23041.1 - 0.0056 16.6 0.1 0.01 15.8 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 AIM23041.1 - 0.0067 17.0 0.4 0.013 16.1 0.4 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AIM23041.1 - 0.0074 16.0 0.1 0.016 14.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 AIM23041.1 - 0.0093 15.4 0.1 0.26 10.7 0.0 2.3 2 1 0 2 2 2 1 Bacterial TniB protein AAA_18 PF13238.6 AIM23041.1 - 0.01 16.4 0.0 0.03 14.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 AIM23041.1 - 0.017 14.6 0.1 1.6 8.2 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_28 PF13521.6 AIM23041.1 - 0.022 15.0 0.1 0.049 13.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 AIM23041.1 - 0.025 13.9 0.5 2.4 7.4 0.0 2.1 2 0 0 2 2 2 0 KaiC AAA_33 PF13671.6 AIM23041.1 - 0.038 14.2 0.4 0.27 11.4 0.1 2.2 2 0 0 2 2 2 0 AAA domain DLIC PF05783.11 AIM23041.1 - 0.052 12.4 0.0 0.078 11.8 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) DEAD PF00270.29 AIM23041.1 - 0.053 13.3 0.0 0.081 12.7 0.0 1.3 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_25 PF13481.6 AIM23041.1 - 0.061 12.9 0.1 0.49 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 AIM23041.1 - 0.1 12.6 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 AIM23041.1 - 0.13 11.9 0.0 0.36 10.4 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ABC_ATPase PF09818.9 AIM23041.1 - 0.14 11.0 0.6 1.5 7.5 0.0 2.5 2 1 0 2 2 2 0 Predicted ATPase of the ABC class cobW PF02492.19 AIM23041.1 - 0.14 11.7 0.5 0.28 10.8 0.2 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 AIM23041.1 - 0.17 10.9 2.8 0.82 8.7 0.2 2.5 2 1 1 3 3 3 0 Type II/IV secretion system protein AAA_5 PF07728.14 AIM23041.1 - 0.2 11.7 0.9 0.6 10.1 0.2 2.1 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 AIM23041.1 - 0.2 11.5 0.0 0.5 10.2 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Roc PF08477.13 AIM23041.1 - 0.22 11.8 0.1 3.6 7.8 0.1 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase BPD_transp_1 PF00528.22 AIM23042.1 - 4.7e-14 52.5 14.0 4.7e-14 52.5 14.0 2.4 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component Cation_efflux PF01545.21 AIM23042.1 - 0.021 14.5 7.2 0.56 9.9 7.5 2.5 2 1 0 2 2 2 0 Cation efflux family TMEM100 PF16311.5 AIM23042.1 - 0.9 9.1 2.4 0.75 9.4 0.1 2.1 2 1 0 2 2 2 0 Transmembrane protein 100 BPD_transp_1 PF00528.22 AIM23043.1 - 1e-32 113.4 14.8 1e-32 113.4 14.8 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component SBP_bac_11 PF13531.6 AIM23044.1 - 3.7e-41 141.4 0.4 4.8e-41 141.0 0.4 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AIM23044.1 - 9.8e-19 68.4 2.3 1.4e-18 67.9 2.3 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 AIM23044.1 - 1.4e-09 38.1 2.2 3e-09 37.1 1.3 1.9 1 1 1 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AIM23044.1 - 1.6e-06 27.7 0.4 2.6e-06 27.0 0.4 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein PBP_like PF12727.7 AIM23044.1 - 0.003 16.7 0.0 0.0049 16.0 0.0 1.4 1 0 0 1 1 1 1 PBP superfamily domain PAD_porph PF04371.15 AIM23044.1 - 0.061 12.6 0.2 0.093 12.0 0.2 1.3 1 0 0 1 1 1 0 Porphyromonas-type peptidyl-arginine deiminase TraW_N PF12477.8 AIM23044.1 - 1.7 8.7 4.2 17 5.5 4.3 2.2 2 0 0 2 2 2 0 Sex factor F TraW protein N terminal Dyp_perox PF04261.12 AIM23045.1 - 1.1e-91 307.3 0.0 1.5e-91 306.8 0.0 1.2 1 0 0 1 1 1 1 Dyp-type peroxidase family DUF1131 PF06572.12 AIM23046.1 - 2.4e-77 258.4 0.1 2.7e-77 258.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1131) DUF2919 PF11143.8 AIM23047.1 - 3.2e-44 150.8 2.9 3.5e-44 150.7 2.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2919) BOF PF04076.13 AIM23048.1 - 1.6e-36 124.5 2.2 2.1e-36 124.1 1.8 1.4 1 1 1 2 2 2 1 Bacterial OB fold (BOF) protein PepSY_2 PF13670.6 AIM23048.1 - 0.38 10.8 3.0 0.62 10.1 0.6 2.2 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Acetyltransf_1 PF00583.25 AIM23049.1 - 2.8e-20 72.7 0.0 3.7e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AIM23049.1 - 1.6e-13 50.7 0.0 2.1e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AIM23049.1 - 3.5e-13 49.8 0.1 6e-13 49.0 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AIM23049.1 - 3e-09 36.7 0.0 4.3e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 AIM23049.1 - 8.4e-08 32.4 0.0 4.5e-06 26.8 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 AIM23049.1 - 4.8e-07 30.0 0.1 6.2e-07 29.7 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AIM23049.1 - 0.00062 19.9 0.0 0.0011 19.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 AIM23049.1 - 0.00084 19.0 0.0 0.0015 18.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AIM23049.1 - 0.0022 18.7 0.0 0.0027 18.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 AIM23049.1 - 0.016 14.8 0.0 0.022 14.3 0.0 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase Acetyltransf_CG PF14542.6 AIM23049.1 - 0.032 14.4 0.0 0.05 13.7 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 AIM23049.1 - 0.033 13.6 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase Gly_acyl_tr_C PF08444.10 AIM23049.1 - 0.13 12.5 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Acetyltransf_13 PF13880.6 AIM23049.1 - 0.15 12.1 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Amidase_3 PF01520.18 AIM23050.1 - 4.8e-49 166.8 0.2 7.3e-49 166.2 0.2 1.3 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase MT0933_antitox PF14013.6 AIM23050.1 - 0.043 14.1 0.5 0.22 11.9 0.1 2.2 2 0 0 2 2 2 0 MT0933-like antitoxin protein Coprogen_oxidas PF01218.18 AIM23051.1 - 1.8e-132 440.5 0.0 2.1e-132 440.4 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase DUF188 PF02639.14 AIM23052.1 - 4.8e-51 171.8 0.0 5.6e-51 171.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized BCR, YaiI/YqxD family COG1671 TonB_dep_Rec PF00593.24 AIM23053.1 - 3.3e-37 129.5 13.4 3.3e-37 129.5 13.4 1.4 2 0 0 2 2 2 1 TonB dependent receptor Plug PF07715.15 AIM23053.1 - 1.6e-09 38.3 5.3 1.6e-09 38.3 5.3 2.4 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain Peptidase_S9_N PF02897.15 AIM23054.1 - 1.2e-93 314.2 1.9 1.4e-93 313.9 1.9 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 AIM23054.1 - 8.2e-65 218.2 1.3 1.2e-64 217.6 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 AIM23054.1 - 0.0023 17.8 0.0 0.0058 16.5 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AIM23054.1 - 0.067 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AIM23054.1 - 0.1 13.2 0.1 0.1 13.2 0.1 3.0 2 2 1 3 3 3 0 Alpha/beta hydrolase family TonB_C PF03544.14 AIM23055.1 - 1.9e-15 57.0 0.0 5.7e-15 55.5 0.0 1.8 1 0 0 1 1 1 1 Gram-negative bacterial TonB protein C-terminal TonB_2 PF13103.6 AIM23055.1 - 1.7e-06 28.2 0.1 4.4e-06 26.9 0.1 1.8 1 1 0 1 1 1 1 TonB C terminal MMR1 PF08505.10 AIM23055.1 - 0.1 12.9 5.8 0.13 12.6 5.8 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein TFIIA PF03153.13 AIM23055.1 - 1.9 8.4 12.1 2.2 8.2 12.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NST1 PF13945.6 AIM23055.1 - 3.1 7.9 7.8 4.1 7.5 7.8 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator Cofac_haem_bdg PF04187.13 AIM23056.1 - 5e-36 124.7 3.8 6.6e-36 124.3 3.8 1.2 1 0 0 1 1 1 1 Haem-binding uptake, Tiki superfamily, ChaN AA_permease PF00324.21 AIM23057.1 - 2e-116 389.4 41.5 2.5e-116 389.1 41.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 AIM23057.1 - 5.8e-43 147.3 44.5 7.3e-43 147.0 44.5 1.0 1 0 0 1 1 1 1 Amino acid permease S-methyl_trans PF02574.16 AIM23058.1 - 1.2e-79 268.0 0.0 1.3e-79 267.8 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase ScsC_N PF18312.1 AIM23058.1 - 0.3 10.9 1.2 30 4.5 0.3 3.2 3 0 0 3 3 3 0 Copper resistance protein ScsC N-terminal domain PTA_PTB PF01515.19 AIM23059.1 - 3.4e-98 328.9 0.0 4.6e-98 328.5 0.0 1.1 1 0 0 1 1 1 1 Phosphate acetyl/butaryl transferase malic PF00390.19 AIM23059.1 - 3.5e-30 105.1 0.2 8.7e-22 77.8 0.1 2.6 2 1 1 3 3 3 2 Malic enzyme, N-terminal domain Malic_M PF03949.15 AIM23059.1 - 2.6e-19 69.5 4.8 9.5e-19 67.7 0.9 2.8 2 1 0 2 2 2 1 Malic enzyme, NAD binding domain ELFV_dehydrog PF00208.21 AIM23059.1 - 0.009 15.8 0.1 0.019 14.7 0.1 1.6 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Amidase_2 PF01510.25 AIM23059.1 - 0.036 14.5 0.0 0.078 13.4 0.0 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-L-alanine amidase DUF2570 PF10828.8 AIM23060.1 - 2.2e-07 30.7 3.6 2.6e-07 30.4 3.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2570) 2OG-FeII_Oxy_2 PF13532.6 AIM23060.1 - 0.012 15.8 0.6 0.013 15.7 0.6 1.0 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily PrgH PF09480.10 AIM23060.1 - 0.013 14.9 1.2 0.015 14.6 1.2 1.0 1 0 0 1 1 1 0 Type III secretion system protein PrgH-EprH (PrgH) HemX PF04375.14 AIM23060.1 - 0.017 14.4 11.1 0.021 14.1 11.1 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF4355 PF14265.6 AIM23060.1 - 0.32 11.2 6.9 0.45 10.7 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) RskA PF10099.9 AIM23060.1 - 0.57 10.4 10.8 0.06 13.6 6.5 1.5 1 1 0 1 1 1 0 Anti-sigma-K factor rskA DUF3584 PF12128.8 AIM23060.1 - 3.4 5.0 12.6 4.2 4.8 12.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Peptidase_M15_4 PF13539.6 AIM23061.1 - 4e-15 56.1 0.1 5.5e-15 55.6 0.1 1.2 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Peptidase_M15_3 PF08291.11 AIM23061.1 - 0.024 14.7 0.0 0.029 14.5 0.0 1.4 1 0 0 1 1 1 0 Peptidase M15 Phage_holin_3_1 PF05106.12 AIM23062.1 - 1.6e-22 79.8 2.0 1.7e-22 79.7 2.0 1.0 1 0 0 1 1 1 1 Phage holin family (Lysis protein S) ThrE_2 PF12821.7 AIM23062.1 - 0.0039 17.3 1.1 0.0044 17.1 1.1 1.1 1 0 0 1 1 1 1 Threonine/Serine exporter, ThrE Phage_holin_3_3 PF16083.5 AIM23062.1 - 0.014 15.5 2.1 0.22 11.7 2.2 2.0 1 1 0 1 1 1 0 LydA holin phage, holin superfamily III HisKA_7TM PF16927.5 AIM23062.1 - 0.038 14.0 0.4 0.046 13.8 0.4 1.0 1 0 0 1 1 1 0 N-terminal 7TM region of histidine kinase Glyco_hydro_18 PF00704.28 AIM23063.1 - 2e-84 284.0 1.2 2.4e-84 283.7 1.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_5_12_2 PF14600.6 AIM23063.1 - 0.00035 20.4 0.7 0.0011 18.8 0.7 1.9 1 0 0 1 1 1 1 Cellulose-binding domain LysR_substrate PF03466.20 AIM23064.1 - 3e-20 72.5 0.0 4.5e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM23064.1 - 4.4e-09 36.2 0.0 8.1e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family LPMO_10 PF03067.15 AIM23065.1 - 9.8e-39 134.0 0.8 1.1e-38 133.8 0.8 1.0 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Sugar-bind PF04198.13 AIM23066.1 - 7.3e-79 264.5 0.4 9.8e-79 264.1 0.4 1.2 1 0 0 1 1 1 1 Putative sugar-binding domain HTH_28 PF13518.6 AIM23066.1 - 1.8e-06 28.0 1.3 3.7e-05 23.8 0.1 3.1 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_23 PF13384.6 AIM23066.1 - 5.1e-06 26.1 2.4 6.4e-05 22.6 0.1 3.2 3 1 1 4 4 3 1 Homeodomain-like domain HTH_24 PF13412.6 AIM23066.1 - 1.3e-05 24.7 0.1 3.3e-05 23.3 0.1 1.8 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.16 AIM23066.1 - 2.7e-05 23.6 0.2 0.00015 21.3 0.3 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_Crp_2 PF13545.6 AIM23066.1 - 6.6e-05 22.8 0.0 0.00027 20.9 0.0 2.1 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain GntR PF00392.21 AIM23066.1 - 0.00067 19.3 0.0 0.0074 15.9 0.0 2.6 3 0 0 3 3 3 1 Bacterial regulatory proteins, gntR family Sigma70_r4_2 PF08281.12 AIM23066.1 - 0.0008 19.0 0.5 0.0039 16.8 0.1 2.3 2 0 0 2 2 2 1 Sigma-70, region 4 MarR_2 PF12802.7 AIM23066.1 - 0.0013 18.6 0.2 0.0074 16.1 0.0 2.3 2 0 0 2 2 2 1 MarR family UPF0175 PF03683.13 AIM23066.1 - 0.02 14.6 0.1 0.051 13.3 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) TrmB PF01978.19 AIM23066.1 - 0.021 14.7 0.1 0.046 13.6 0.1 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.20 AIM23066.1 - 0.026 14.8 0.1 0.085 13.2 0.1 1.8 1 0 0 1 1 1 0 Transcriptional regulator HTH_10 PF04967.12 AIM23066.1 - 0.032 14.0 0.1 0.17 11.7 0.0 2.2 2 0 0 2 2 2 0 HTH DNA binding domain MarR PF01047.22 AIM23066.1 - 0.033 14.1 0.0 0.082 12.9 0.0 1.6 1 0 0 1 1 1 0 MarR family HTH_11 PF08279.12 AIM23066.1 - 0.033 14.1 0.1 0.15 12.0 0.0 2.2 2 0 0 2 2 2 0 HTH domain HTH_29 PF13551.6 AIM23066.1 - 0.037 14.0 1.8 0.086 12.9 0.0 2.4 3 0 0 3 3 3 0 Winged helix-turn helix TFIIE_alpha PF02002.17 AIM23066.1 - 0.048 13.5 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 TFIIE alpha subunit Phage_antitermQ PF06530.12 AIM23066.1 - 0.071 13.0 0.2 0.16 11.9 0.2 1.6 1 0 0 1 1 1 0 Phage antitermination protein Q HTH_psq PF05225.16 AIM23066.1 - 0.084 12.6 0.1 2 8.2 0.0 2.4 2 0 0 2 2 2 0 helix-turn-helix, Psq domain DUF515 PF04415.12 AIM23066.1 - 0.09 11.1 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF134 PF02001.16 AIM23066.1 - 0.11 13.0 0.0 0.41 11.2 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function DUF134 Crp PF00325.20 AIM23066.1 - 0.12 12.1 0.1 0.45 10.2 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, crp family VirE3 PF06661.11 AIM23066.1 - 0.13 11.5 0.1 0.49 9.6 0.0 1.8 2 0 0 2 2 2 0 VirE3 Dak2 PF02734.17 AIM23067.1 - 7.4e-49 166.0 3.2 8.6e-49 165.8 3.2 1.0 1 0 0 1 1 1 1 DAK2 domain Dak1 PF02733.17 AIM23068.1 - 3.4e-111 371.1 0.6 4.2e-111 370.8 0.6 1.0 1 0 0 1 1 1 1 Dak1 domain adh_short_C2 PF13561.6 AIM23069.1 - 3.4e-71 239.5 4.4 4e-71 239.3 4.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AIM23069.1 - 3.6e-61 206.0 0.7 4.5e-61 205.7 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AIM23069.1 - 1.9e-12 47.5 1.8 2.7e-12 47.0 1.8 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AIM23069.1 - 1.4e-05 24.7 0.6 2.9e-05 23.6 0.5 1.6 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 AIM23069.1 - 0.006 15.7 1.2 0.009 15.1 1.2 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 AIM23069.1 - 0.0098 15.3 0.0 0.017 14.5 0.0 1.4 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 AIM23069.1 - 0.013 15.4 2.5 0.018 14.9 2.5 1.3 1 0 0 1 1 1 0 NAD(P)H-binding TrkA_N PF02254.18 AIM23069.1 - 0.067 13.5 0.4 0.13 12.5 0.4 1.4 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 AIM23069.1 - 0.073 13.0 0.8 0.15 12.0 0.8 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NmrA PF05368.13 AIM23069.1 - 0.1 12.1 3.3 0.07 12.7 1.6 1.6 2 0 0 2 2 2 0 NmrA-like family HI0933_like PF03486.14 AIM23069.1 - 0.11 11.1 0.7 0.19 10.4 0.7 1.3 1 0 0 1 1 1 0 HI0933-like protein Sigma70_r3 PF04539.16 AIM23069.1 - 0.16 12.1 0.2 14 5.9 0.1 2.6 2 1 1 3 3 3 0 Sigma-70 region 3 MFS_1 PF07690.16 AIM23070.1 - 8.4e-31 107.2 82.5 2.7e-20 72.6 49.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 AIM23070.1 - 5.8e-06 25.0 12.0 0.0022 16.5 5.8 2.3 2 0 0 2 2 2 2 Transmembrane secretion effector MFS_1_like PF12832.7 AIM23070.1 - 0.0006 18.8 0.5 0.0006 18.8 0.5 3.1 2 2 1 3 3 3 2 MFS_1 like family DUF5353 PF17304.2 AIM23070.1 - 9 6.1 8.4 4 7.3 0.7 3.1 2 0 0 2 2 2 0 Family of unknown function (DUF5353) ADH_N PF08240.12 AIM23071.1 - 1.2e-28 99.2 1.4 1.8e-28 98.6 0.3 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AIM23071.1 - 2.3e-20 72.9 0.0 3.7e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AIM23071.1 - 0.13 13.4 0.1 2 9.5 0.1 2.3 1 1 0 1 1 1 0 Zinc-binding dehydrogenase LacAB_rpiB PF02502.18 AIM23072.1 - 3.9e-49 166.2 0.1 4.4e-49 166.1 0.1 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase DUF2000 PF09391.10 AIM23072.1 - 0.053 13.5 0.0 0.14 12.0 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2000) TAL_FSA PF00923.19 AIM23073.1 - 2.1e-100 335.8 0.0 2.4e-100 335.6 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Transketolase_N PF00456.21 AIM23074.1 - 1.5e-170 566.6 0.1 2.4e-170 565.8 0.1 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 AIM23074.1 - 7.1e-45 152.9 0.8 1.5e-44 151.8 0.0 1.9 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 AIM23074.1 - 3.1e-20 72.3 0.5 6.1e-20 71.4 0.2 1.7 2 0 0 2 2 2 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 AIM23074.1 - 4.2e-06 26.2 0.0 0.0063 15.7 0.0 2.5 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 AIM23074.1 - 4.3e-05 23.4 0.4 0.01 15.7 0.4 3.1 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Mur_ligase_C PF02875.21 AIM23074.1 - 0.11 12.8 0.0 0.39 11.0 0.0 1.9 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain CP12 PF02672.15 AIM23074.1 - 0.83 10.4 2.3 9.4 7.1 0.0 3.1 3 0 0 3 3 3 0 CP12 domain NUDIX PF00293.28 AIM23075.1 - 4.4e-11 43.0 0.0 5.6e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain PilJ PF13675.6 AIM23076.1 - 3.8e-23 81.7 5.3 3.8e-23 81.7 5.3 3.7 3 1 0 3 3 3 1 Type IV pili methyl-accepting chemotaxis transducer N-term HisKA_3 PF07730.13 AIM23076.1 - 3.2e-16 59.6 3.8 3.2e-16 59.6 3.8 3.9 4 0 0 4 4 4 1 Histidine kinase HAMP PF00672.25 AIM23076.1 - 2.9e-11 43.6 0.1 1.1e-10 41.7 0.1 2.2 1 0 0 1 1 1 1 HAMP domain HATPase_c PF02518.26 AIM23076.1 - 1.9e-10 41.3 0.4 1.2e-09 38.7 0.4 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PI3K_P85_iSH2 PF16454.5 AIM23076.1 - 0.0069 16.0 6.1 0.06 13.0 1.8 2.6 2 0 0 2 2 2 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain HATPase_c_2 PF13581.6 AIM23076.1 - 0.011 15.7 0.3 0.034 14.1 0.1 2.0 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 AIM23076.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AIM23077.1 - 1.6e-29 102.3 0.1 2.7e-29 101.6 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AIM23077.1 - 1.8e-23 81.9 0.7 2.8e-23 81.2 0.7 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4 PF04545.16 AIM23077.1 - 1.2e-06 28.0 0.4 2.9e-06 26.7 0.4 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 AIM23077.1 - 4.9e-06 26.1 0.1 9.3e-06 25.2 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 AIM23077.1 - 0.00023 20.9 0.2 0.00053 19.7 0.2 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_10 PF04967.12 AIM23077.1 - 0.0006 19.6 1.0 0.0062 16.3 1.0 2.4 1 1 0 1 1 1 1 HTH DNA binding domain HTH_24 PF13412.6 AIM23077.1 - 0.00077 19.0 0.3 0.0018 17.8 0.1 1.6 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 AIM23077.1 - 0.0022 18.1 0.0 0.0065 16.6 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 AIM23077.1 - 0.0058 16.0 0.0 0.015 14.7 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_30 PF13556.6 AIM23077.1 - 0.039 13.8 0.5 0.36 10.7 0.2 2.5 3 0 0 3 3 3 0 PucR C-terminal helix-turn-helix domain HTH_1 PF00126.27 AIM23077.1 - 0.055 13.4 1.5 0.085 12.8 0.1 2.1 2 1 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_20 PF12840.7 AIM23077.1 - 0.067 13.3 0.8 0.22 11.6 0.1 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain DUF2089 PF09862.9 AIM23077.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) HTH_43 PF09904.9 AIM23078.1 - 1.2e-38 130.9 0.0 1.3e-38 130.8 0.0 1.0 1 0 0 1 1 1 1 Winged helix-turn helix ACR_tran PF00873.19 AIM23079.1 - 0 1384.3 17.1 0 1384.2 17.1 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AIM23079.1 - 7.6e-12 44.8 43.0 1.5e-05 24.2 22.8 3.7 2 1 1 3 3 3 2 MMPL family SecD_SecF PF02355.16 AIM23079.1 - 3.1e-08 33.2 23.6 9.7e-05 21.8 2.4 2.3 2 0 0 2 2 2 2 Protein export membrane protein EC042_2821 PF18740.1 AIM23079.1 - 0.061 13.2 0.3 0.49 10.3 0.1 2.1 1 1 1 2 2 2 0 EC042_2821-lke REase DUF4128 PF13554.6 AIM23079.1 - 0.069 13.2 0.4 1.7 8.7 0.0 2.9 3 0 0 3 3 3 0 Bacteriophage related domain of unknown function T3SS_needle_E PF08988.10 AIM23079.1 - 0.21 11.8 1.6 4.4 7.5 0.1 2.8 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle Patched PF02460.18 AIM23079.1 - 0.48 8.4 14.7 0.8 7.7 14.7 1.3 1 0 0 1 1 1 0 Patched family TPR_5 PF12688.7 AIM23080.1 - 1.3e-13 51.2 1.9 3.1e-13 50.0 0.4 1.9 1 1 0 2 2 2 1 Tetratrico peptide repeat TPR_16 PF13432.6 AIM23080.1 - 2.4e-09 37.7 9.9 2.1e-05 25.1 1.8 3.5 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 AIM23080.1 - 5.8e-07 29.8 12.5 0.00024 21.7 0.3 3.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 AIM23080.1 - 3e-06 26.8 7.6 0.0062 16.3 0.0 4.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 AIM23080.1 - 6.7e-06 25.8 12.9 0.0052 16.8 0.1 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 AIM23080.1 - 0.0002 21.2 6.8 1.6 8.9 0.0 4.5 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 AIM23080.1 - 0.0002 21.3 2.4 0.99 9.8 0.0 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 AIM23080.1 - 0.0085 15.9 5.3 11 6.1 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.6 AIM23080.1 - 0.018 15.3 4.3 1.8 8.9 0.5 2.7 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 AIM23080.1 - 0.027 14.7 11.2 0.29 11.5 0.0 2.8 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 AIM23080.1 - 0.077 13.4 4.0 6.4 7.4 0.0 4.0 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 AIM23080.1 - 0.74 10.4 12.1 0.52 10.9 0.7 2.7 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 AIM23080.1 - 0.78 9.9 10.1 0.11 12.6 0.7 2.6 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 AIM23080.1 - 1.7 9.4 0.1 1.7 9.4 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Acetyltransf_10 PF13673.7 AIM23081.1 - 4.7e-12 45.9 0.0 6.1e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AIM23081.1 - 3.5e-11 43.4 0.0 4.3e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AIM23081.1 - 3.5e-10 40.2 0.0 4.5e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AIM23081.1 - 2.4e-09 37.4 0.0 1.1e-08 35.2 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AIM23081.1 - 0.00014 21.8 0.0 0.00024 21.0 0.0 1.4 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 AIM23081.1 - 0.0071 16.5 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase GerE PF00196.19 AIM23082.1 - 1.8e-11 43.4 0.1 2.8e-11 42.8 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family ArsC PF03960.15 AIM23083.1 - 6e-16 58.2 0.0 7e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 ArsC family Glutaredoxin PF00462.24 AIM23083.1 - 0.042 14.1 0.0 0.066 13.4 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin Peptidase_M20 PF01546.28 AIM23084.1 - 4.9e-45 153.8 0.1 5.9e-45 153.5 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AIM23084.1 - 6.2e-25 87.2 0.0 1.3e-24 86.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 AIM23084.1 - 0.012 15.4 0.0 0.061 13.0 0.0 1.9 2 0 0 2 2 2 0 Peptidase family M28 Peptidase_M18 PF02127.15 AIM23084.1 - 0.14 10.9 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Aminopeptidase I zinc metalloprotease (M18) VanY PF02557.17 AIM23085.1 - 9.5e-39 132.2 0.0 1.3e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase UPF0370 PF13980.6 AIM23086.1 - 2.2e-36 123.6 6.1 2.4e-36 123.5 6.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0370) PYST-C1 PF09690.10 AIM23086.1 - 0.062 13.1 0.0 0.076 12.8 0.0 1.1 1 0 0 1 1 1 0 Plasmodium yoelii subtelomeric region (PYST-C1) DUF2897 PF11446.8 AIM23086.1 - 1 9.3 5.9 1.3 9.0 5.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2897) Abhydrolase_2 PF02230.16 AIM23087.1 - 2.5e-38 132.0 0.1 2.9e-38 131.9 0.1 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.18 AIM23087.1 - 3.9e-09 36.4 0.2 6.3e-09 35.7 0.2 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 AIM23087.1 - 6.3e-07 29.1 2.8 0.0002 20.9 0.2 2.8 3 0 0 3 3 3 2 Prolyl oligopeptidase family FSH1 PF03959.13 AIM23087.1 - 0.00041 20.1 0.1 0.00076 19.2 0.1 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 AIM23087.1 - 0.0048 17.5 7.7 0.12 12.9 2.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AIM23087.1 - 0.09 12.0 2.7 5 6.3 0.1 2.7 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Palm_thioest PF02089.15 AIM23087.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.4 1 1 0 1 1 1 0 Palmitoyl protein thioesterase tRNA_bind_3 PF17176.4 AIM23088.1 - 7.4e-42 142.4 3.7 2.6e-41 140.7 3.7 2.0 1 0 0 1 1 1 1 tRNA-binding domain Helicase_RecD PF05127.14 AIM23088.1 - 3.2e-38 131.3 0.2 8.7e-36 123.4 0.2 2.3 1 1 0 1 1 1 1 Helicase GNAT_acetyltr_2 PF13718.6 AIM23088.1 - 7.9e-25 87.6 0.0 9.7e-15 54.6 0.0 2.2 1 1 1 2 2 2 2 GNAT acetyltransferase 2 Acetyltransf_7 PF13508.7 AIM23088.1 - 2.8e-06 27.7 0.0 1.5e-05 25.4 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF1726 PF08351.11 AIM23088.1 - 4.1e-06 26.6 0.0 7.7e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) Acetyltransf_10 PF13673.7 AIM23088.1 - 5.4e-05 23.1 0.0 0.00036 20.5 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain AAA_30 PF13604.6 AIM23088.1 - 0.004 16.9 1.0 0.012 15.3 1.0 1.9 1 1 0 1 1 1 1 AAA domain PanZ PF12568.8 AIM23088.1 - 0.032 14.0 0.2 0.085 12.6 0.2 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_1 PF00583.25 AIM23088.1 - 0.037 14.2 0.0 0.16 12.2 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Acetyltransf_13 PF13880.6 AIM23088.1 - 0.18 11.8 0.9 0.43 10.6 0.2 1.9 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase Zn_peptidase PF04228.13 AIM23089.1 - 1.5e-128 428.3 1.8 1.7e-128 428.1 1.8 1.0 1 0 0 1 1 1 1 Putative neutral zinc metallopeptidase Aspzincin_M35 PF14521.6 AIM23089.1 - 0.015 15.8 0.2 0.029 14.9 0.0 1.5 2 0 0 2 2 2 0 Lysine-specific metallo-endopeptidase Reprolysin_3 PF13582.6 AIM23089.1 - 0.12 12.9 0.0 0.22 12.0 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like SAICAR_synt PF01259.18 AIM23090.1 - 3.5e-60 203.7 0.0 4e-60 203.6 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase Lipoprotein_18 PF06804.11 AIM23091.1 - 9.9e-112 373.1 2.2 1.1e-111 372.9 2.2 1.0 1 0 0 1 1 1 1 NlpB/DapX lipoprotein Pilus_CpaD PF09476.10 AIM23091.1 - 0.035 13.8 0.1 1.9 8.2 0.0 2.3 2 0 0 2 2 2 0 Pilus biogenesis CpaD protein (pilus_cpaD) P22_portal PF16510.5 AIM23091.1 - 0.049 12.2 1.3 0.065 11.8 1.3 1.2 1 0 0 1 1 1 0 Phage P22-like portal protein DHDPS PF00701.22 AIM23092.1 - 3.2e-114 380.5 0.1 3.6e-114 380.4 0.1 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family YjgF_endoribonc PF14588.6 AIM23092.1 - 0.18 12.0 1.1 0.7 10.0 1.0 2.0 1 1 1 2 2 2 0 YjgF/chorismate_mutase-like, putative endoribonuclease ACT_6 PF13740.6 AIM23093.1 - 1.4e-26 92.3 0.1 7.3e-25 86.8 0.0 2.4 2 1 0 2 2 2 1 ACT domain ACT PF01842.25 AIM23093.1 - 2.7e-07 30.2 0.0 0.00014 21.6 0.0 2.2 2 0 0 2 2 2 2 ACT domain ACT_4 PF13291.6 AIM23093.1 - 2.5e-05 24.8 0.0 0.098 13.3 0.0 2.5 3 0 0 3 3 3 2 ACT domain AhpC-TSA PF00578.21 AIM23094.1 - 3.8e-39 133.4 0.0 4.5e-39 133.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AIM23094.1 - 3.7e-28 98.1 0.0 4.1e-28 98.0 0.0 1.0 1 0 0 1 1 1 1 Redoxin SCO1-SenC PF02630.14 AIM23094.1 - 7.1e-06 26.0 0.0 1.2e-05 25.3 0.0 1.4 1 1 0 1 1 1 1 SCO1/SenC AhpC-TSA_2 PF13911.6 AIM23094.1 - 1.2e-05 25.4 0.0 1.5e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme DUF899 PF05988.12 AIM23094.1 - 0.0011 18.5 0.0 0.0012 18.4 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) GSHPx PF00255.19 AIM23094.1 - 0.0072 15.9 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AI-2E_transport PF01594.16 AIM23095.1 - 1.6e-78 264.1 40.2 1.8e-78 264.0 40.2 1.0 1 0 0 1 1 1 1 AI-2E family transporter B3_4 PF03483.17 AIM23097.1 - 1.8e-15 57.1 0.0 2.3e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 B3/4 domain HTH_3 PF01381.22 AIM23098.1 - 7.1e-14 51.6 0.3 1.4e-13 50.7 0.3 1.5 1 0 0 1 1 1 1 Helix-turn-helix Cupin_2 PF07883.11 AIM23098.1 - 1.9e-10 40.3 0.1 4.1e-10 39.2 0.1 1.5 1 0 0 1 1 1 1 Cupin domain HTH_19 PF12844.7 AIM23098.1 - 3e-09 36.8 0.0 4.6e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 AIM23098.1 - 7.6e-09 35.8 0.0 1.4e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain AraC_binding PF02311.19 AIM23098.1 - 6.8e-05 22.8 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain HTH_25 PF13413.6 AIM23098.1 - 8.5e-05 22.3 0.1 0.0029 17.4 0.1 2.5 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_26 PF13443.6 AIM23098.1 - 0.00018 21.8 0.1 0.00031 21.1 0.1 1.4 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_37 PF13744.6 AIM23098.1 - 0.033 14.2 0.1 0.052 13.5 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain RHH_1 PF01402.21 AIM23098.1 - 0.11 12.5 0.1 13 5.9 0.1 2.4 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family HHH_6 PF14579.6 AIM23098.1 - 0.13 12.5 0.1 0.28 11.5 0.1 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif TetR_N PF00440.23 AIM23098.1 - 0.16 11.8 0.1 0.61 9.9 0.0 2.0 3 0 0 3 3 3 0 Bacterial regulatory proteins, tetR family Acetyltransf_1 PF00583.25 AIM23099.1 - 1.2e-06 28.7 0.0 1.4e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AIM23099.1 - 4.8e-06 26.5 0.0 6.3e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AIM23099.1 - 5.5e-06 26.7 0.0 7.8e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AIM23099.1 - 4.9e-05 23.2 0.0 0.00011 22.1 0.0 1.6 1 1 0 1 1 1 1 FR47-like protein LysE PF01810.18 AIM23100.1 - 6.6e-23 81.2 11.7 8.1e-23 80.9 11.7 1.1 1 0 0 1 1 1 1 LysE type translocator HTH_24 PF13412.6 AIM23101.1 - 3.5e-21 74.5 0.2 4.9e-21 74.0 0.2 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 AIM23101.1 - 1.1e-19 69.9 0.7 1.9e-19 69.2 0.7 1.4 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain AsnC_trans_reg PF01037.21 AIM23101.1 - 2.1e-19 69.3 0.0 3.1e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_20 PF12840.7 AIM23101.1 - 4.4e-08 33.1 0.2 7.4e-08 32.3 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_11 PF08279.12 AIM23101.1 - 2.5e-06 27.4 0.0 3.9e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 HTH domain MarR_2 PF12802.7 AIM23101.1 - 3.7e-06 26.7 1.6 6.4e-06 26.0 0.8 1.8 2 1 0 2 2 1 1 MarR family HTH_IclR PF09339.10 AIM23101.1 - 1.3e-05 24.8 0.4 3e-05 23.7 0.1 1.7 2 0 0 2 2 2 1 IclR helix-turn-helix domain MarR PF01047.22 AIM23101.1 - 6e-05 22.9 0.5 9.4e-05 22.3 0.0 1.5 2 0 0 2 2 1 1 MarR family HTH_47 PF16221.5 AIM23101.1 - 0.00058 19.4 0.0 0.0023 17.5 0.0 1.8 2 0 0 2 2 2 1 winged helix-turn-helix HTH_Crp_2 PF13545.6 AIM23101.1 - 0.0018 18.2 0.1 0.0043 17.0 0.1 1.7 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_DeoR PF08220.12 AIM23101.1 - 0.0059 16.3 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HxlR PF01638.17 AIM23101.1 - 0.0095 15.8 0.0 0.99 9.3 0.0 2.2 1 1 1 2 2 2 2 HxlR-like helix-turn-helix HTH_5 PF01022.20 AIM23101.1 - 0.011 15.5 0.1 0.018 14.9 0.1 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_28 PF13518.6 AIM23101.1 - 0.015 15.4 0.1 0.025 14.7 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain GntR PF00392.21 AIM23101.1 - 0.02 14.6 0.2 0.05 13.2 0.1 1.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family Rrf2 PF02082.20 AIM23101.1 - 0.024 15.0 0.0 0.069 13.5 0.0 1.7 2 0 0 2 2 2 0 Transcriptional regulator HTH_CodY PF08222.11 AIM23101.1 - 0.029 13.9 0.1 0.05 13.2 0.1 1.4 1 0 0 1 1 1 0 CodY helix-turn-helix domain TrmB PF01978.19 AIM23101.1 - 0.074 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB E3_UFM1_ligase PF09743.9 AIM23101.1 - 0.095 12.3 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 E3 UFM1-protein ligase 1 LexA_DNA_bind PF01726.16 AIM23101.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 LexA DNA binding domain Pyr_redox_2 PF07992.14 AIM23102.1 - 1.8e-38 132.5 3.3 2.1e-38 132.2 3.3 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AIM23102.1 - 1.2e-05 25.7 2.6 2.2e-05 24.9 0.4 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AIM23102.1 - 0.00063 19.9 2.8 0.062 13.5 0.3 3.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 AIM23102.1 - 0.0015 18.5 4.7 0.38 10.7 0.1 3.8 2 2 2 4 4 4 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 AIM23102.1 - 0.007 15.7 0.0 1.2 8.3 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AIM23102.1 - 0.11 11.5 7.0 6 5.8 0.0 3.6 4 0 0 4 4 4 0 Glucose inhibited division protein A HI0933_like PF03486.14 AIM23102.1 - 0.48 9.1 6.5 3.4 6.3 0.0 3.3 3 0 0 3 3 3 0 HI0933-like protein Lycopene_cycl PF05834.12 AIM23102.1 - 5.7 5.9 5.8 11 4.9 0.3 2.9 3 0 0 3 3 3 0 Lycopene cyclase protein Rrf2 PF02082.20 AIM23103.1 - 6.3e-25 87.3 0.1 2e-24 85.7 0.0 1.7 2 0 0 2 2 2 1 Transcriptional regulator HTH_24 PF13412.6 AIM23103.1 - 0.0014 18.2 0.0 0.0024 17.4 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 AIM23103.1 - 0.0034 17.2 0.1 0.013 15.3 0.0 1.8 2 0 0 2 2 2 1 MarR family HTH_Crp_2 PF13545.6 AIM23103.1 - 0.01 15.8 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain MarR PF01047.22 AIM23103.1 - 0.019 14.9 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 MarR family tify PF06200.14 AIM23103.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 tify domain TrmB PF01978.19 AIM23103.1 - 0.15 11.9 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HrcA_DNA-bdg PF03444.15 AIM23103.1 - 0.19 11.4 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Peptidase_M48 PF01435.18 AIM23104.1 - 1.1e-27 97.2 0.4 2.2e-27 96.1 0.1 1.7 2 0 0 2 2 2 1 Peptidase family M48 TPR_19 PF14559.6 AIM23104.1 - 2.8e-15 56.6 15.1 4.3e-11 43.2 4.4 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 AIM23104.1 - 1.3e-07 31.9 12.3 0.0022 18.6 0.0 5.1 5 2 1 6 6 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 AIM23104.1 - 0.0026 18.4 15.8 0.023 15.4 2.1 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat DUF4157 PF13699.6 AIM23104.1 - 0.018 15.3 1.4 0.047 13.9 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4157) TPR_3 PF07720.12 AIM23104.1 - 0.019 14.9 0.3 2.4 8.3 0.3 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 AIM23104.1 - 0.043 13.9 6.4 11 6.4 0.1 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 AIM23104.1 - 0.049 14.3 6.5 2.8 8.8 0.0 4.4 4 0 0 4 4 3 0 Tetratricopeptide repeat RPW8 PF05659.11 AIM23104.1 - 0.16 11.6 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF2268 PF10026.9 AIM23104.1 - 0.17 11.4 0.3 0.57 9.7 0.2 1.8 1 1 1 2 2 2 0 Predicted Zn-dependent protease (DUF2268) TPR_1 PF00515.28 AIM23104.1 - 0.22 11.4 5.2 6.4 6.8 1.3 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 AIM23104.1 - 0.46 11.3 10.2 4.8 8.1 0.5 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat ArsC PF03960.15 AIM23105.1 - 2.3e-22 78.8 0.1 2.6e-22 78.6 0.1 1.1 1 0 0 1 1 1 1 ArsC family DUF1687 PF07955.11 AIM23105.1 - 0.00014 22.3 0.0 0.00068 20.1 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) Glutaredoxin PF00462.24 AIM23105.1 - 0.00017 21.7 0.1 0.00069 19.8 0.0 1.8 1 1 1 2 2 2 1 Glutaredoxin SAP PF02037.27 AIM23105.1 - 0.036 13.8 0.1 0.12 12.1 0.1 2.0 1 0 0 1 1 1 0 SAP domain DUF4332 PF14229.6 AIM23105.1 - 0.048 13.9 0.1 0.13 12.5 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4332) Bac_DnaA PF00308.18 AIM23107.1 - 1.8e-13 50.8 0.0 2.2e-13 50.5 0.0 1.0 1 0 0 1 1 1 1 Bacterial dnaA protein Apolipoprotein PF01442.18 AIM23108.1 - 2.1e-06 27.7 21.8 3.7e-06 27.0 21.8 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain YtxH PF12732.7 AIM23108.1 - 1.1e-05 25.9 38.5 0.022 15.3 13.2 3.3 1 1 2 3 3 3 3 YtxH-like protein DivIVA PF05103.13 AIM23108.1 - 0.00072 19.7 40.3 0.035 14.2 12.2 3.1 1 1 2 3 3 3 2 DivIVA protein DUF883 PF05957.13 AIM23108.1 - 0.0095 16.5 28.0 3.1 8.5 15.3 3.6 1 1 3 4 4 4 4 Bacterial protein of unknown function (DUF883) ATP-synt_B PF00430.18 AIM23108.1 - 0.02 15.0 47.6 0.94 9.6 18.4 3.0 1 1 2 3 3 3 0 ATP synthase B/B' CF(0) V-ATPase_G_2 PF16999.5 AIM23108.1 - 0.038 14.4 36.5 0.81 10.1 19.8 3.0 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit Gp-FAR-1 PF05823.12 AIM23108.1 - 0.2 12.0 19.4 0.42 10.9 14.5 2.0 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) AI-2E_transport PF01594.16 AIM23108.1 - 0.72 8.9 2.3 0.75 8.9 0.3 1.9 2 1 0 2 2 2 0 AI-2E family transporter Phasin PF05597.11 AIM23108.1 - 0.89 9.6 21.7 2.2 8.3 4.8 2.9 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) LMBR1 PF04791.16 AIM23108.1 - 1 8.2 9.0 1.1 8.0 9.0 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1451 PF07295.11 AIM23108.1 - 1.6 8.7 16.6 0.28 11.2 11.8 1.8 1 1 1 2 2 2 0 Zinc-ribbon containing domain TPR_MLP1_2 PF07926.12 AIM23108.1 - 1.7 8.7 32.0 0.19 11.8 15.7 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Calc_CGRP_IAPP PF00214.19 AIM23108.1 - 2.7 8.4 5.0 7.2 7.0 5.0 1.9 1 1 0 1 1 1 0 Calcitonin / CGRP / IAPP family Mitofilin PF09731.9 AIM23108.1 - 3.8 6.2 31.7 6.1 5.6 31.7 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein HrpE PF06188.12 AIM23108.1 - 5.1 6.9 28.4 14 5.4 9.5 3.3 1 1 2 3 3 3 0 HrpE/YscL/FliH and V-type ATPase subunit E KfrA_N PF11740.8 AIM23108.1 - 5.7 7.7 29.0 8.4 7.1 12.3 2.3 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term CorA PF01544.18 AIM23108.1 - 8.9 5.5 6.2 12 5.1 6.2 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein JHD PF17811.1 AIM23108.1 - 9.1 6.9 9.4 4.9 7.7 1.2 2.4 1 1 0 2 2 2 0 Jumonji helical domain Transgly_assoc PF04226.13 AIM23109.1 - 1e-15 57.7 10.2 1e-15 57.7 10.2 2.2 1 1 1 2 2 2 1 Transglycosylase associated protein DUF5518 PF17647.1 AIM23109.1 - 0.0062 16.7 16.8 0.0075 16.4 16.8 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5518) DUF2632 PF10943.8 AIM23109.1 - 0.17 11.5 5.1 0.19 11.3 5.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2632) DUF2306 PF10067.9 AIM23109.1 - 0.38 11.0 4.4 0.24 11.6 2.6 1.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2306) ECF_trnsprt PF12822.7 AIM23109.1 - 0.53 10.4 12.3 2.8 8.0 12.6 1.7 1 1 0 1 1 1 0 ECF transporter, substrate-specific component Phage_holin_4_2 PF04020.13 AIM23109.1 - 0.95 10.2 9.4 4.4 8.0 2.3 2.0 1 1 1 2 2 2 0 Mycobacterial 4 TMS phage holin, superfamily IV 7TM-7TMR_HD PF07698.11 AIM23109.1 - 1.1 9.0 9.3 0.31 10.8 5.3 1.8 1 1 0 2 2 2 0 7TM receptor with intracellular HD hydrolase SLATT_fungal PF18142.1 AIM23109.1 - 1.2 9.2 3.0 1.6 8.7 2.0 1.8 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain Trep_Strep PF09605.10 AIM23109.1 - 4.5 7.2 16.1 1.3 8.9 8.0 2.2 1 1 1 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) Xan_ur_permease PF00860.20 AIM23110.1 - 1.9e-106 356.1 43.0 2.7e-106 355.6 43.0 1.2 1 0 0 1 1 1 1 Permease family UPRTase PF14681.6 AIM23111.1 - 1.2e-64 217.6 0.0 1.3e-64 217.4 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 AIM23111.1 - 7.3e-14 51.6 0.3 1e-13 51.1 0.3 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.6 AIM23111.1 - 0.029 14.4 0.0 0.047 13.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain AIRS_C PF02769.22 AIM23112.1 - 1.9e-39 135.3 0.1 3.1e-39 134.6 0.1 1.4 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 AIM23112.1 - 2.6e-16 60.1 0.6 5.2e-16 59.1 0.6 1.6 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain DUF1949 PF09186.11 AIM23112.1 - 0.14 12.0 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1949) Formyl_trans_N PF00551.19 AIM23113.1 - 2.9e-67 225.9 0.2 3.3e-67 225.7 0.2 1.0 1 0 0 1 1 1 1 Formyl transferase Acetyltransf_3 PF13302.7 AIM23114.1 - 4e-22 79.4 0.0 4.8e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AIM23114.1 - 3e-14 53.3 0.1 4.2e-14 52.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AIM23114.1 - 5e-09 36.5 0.1 9.6e-09 35.6 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 AIM23114.1 - 1.9e-07 30.8 0.0 6.2e-07 29.2 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AIM23114.1 - 1.2e-05 25.2 0.1 1.7e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AIM23114.1 - 2.7e-05 24.4 0.1 3.2e-05 24.1 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AIM23114.1 - 3.9e-05 23.5 0.0 8.4e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 AIM23114.1 - 0.063 13.4 0.1 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase GNAT_acetyltran PF12746.7 AIM23114.1 - 0.11 12.0 0.0 0.28 10.7 0.0 1.6 1 1 0 1 1 1 0 GNAT acetyltransferase MFS18 PF17352.2 AIM23115.1 - 1.3 9.4 3.9 1 9.7 1.0 2.2 1 1 0 2 2 2 0 Male Flower Specific protein 18 DUF596 PF04591.12 AIM23117.1 - 2.8e-18 65.8 2.0 4.7e-18 65.1 2.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF596 DUF637 PF04830.13 AIM23118.1 - 3.1e-51 173.6 23.1 3.1e-51 173.6 23.1 3.9 3 0 0 3 3 3 1 Possible hemagglutinin (DUF637) Haemagg_act PF05860.13 AIM23118.1 - 3.6e-34 117.2 3.5 3.6e-34 117.2 3.5 2.8 2 0 0 2 2 2 1 haemagglutination activity domain Fil_haemagg_2 PF13332.6 AIM23118.1 - 0.018 15.2 0.7 0.018 15.2 0.7 10.9 6 2 3 11 11 11 0 Hemagglutinin repeat ShlB PF03865.13 AIM23119.1 - 1.7e-88 297.1 9.9 2.3e-88 296.6 9.9 1.2 1 0 0 1 1 1 1 Haemolysin secretion/activation protein ShlB/FhaC/HecB POTRA_2 PF08479.11 AIM23119.1 - 1.7e-23 82.3 0.1 7.2e-23 80.2 0.0 2.0 2 0 0 2 2 2 1 POTRA domain, ShlB-type POTRA_3 PF17287.2 AIM23119.1 - 3.7e-22 77.5 2.7 5.3e-22 77.0 0.9 2.3 2 0 0 2 2 2 1 POTRA domain AbiEi_3_N PF17194.4 AIM23119.1 - 0.079 13.0 0.3 0.29 11.2 0.0 2.0 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin N-terminal domain POTRA PF07244.15 AIM23119.1 - 0.11 13.0 0.0 0.67 10.6 0.0 2.2 2 0 0 2 2 2 0 Surface antigen variable number repeat STALD PF18185.1 AIM23120.1 - 1.8e-72 243.1 0.0 3.6e-72 242.1 0.0 1.5 2 0 0 2 2 2 1 Sir2- and TIR-associating SLOG family SIR2_2 PF13289.6 AIM23120.1 - 3.3e-30 105.1 0.4 8.8e-30 103.7 0.4 1.7 1 0 0 1 1 1 1 SIR2-like domain LDcluster4 PF18306.1 AIM23120.1 - 0.13 11.8 0.0 1.5 8.4 0.0 2.2 2 0 0 2 2 2 0 SLOG cluster4 family DUF1863 PF08937.11 AIM23121.1 - 1.4e-24 86.9 0.0 2.9e-24 85.8 0.0 1.5 2 0 0 2 2 2 1 MTH538 TIR-like domain (DUF1863) TIR_2 PF13676.6 AIM23121.1 - 0.0066 17.0 0.0 0.012 16.2 0.0 1.5 2 0 0 2 2 2 1 TIR domain ABC_tran PF00005.27 AIM23122.1 - 2.6e-30 105.7 0.0 3.8e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIM23122.1 - 2.7e-13 50.4 0.6 1.5e-06 28.3 0.3 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 AIM23122.1 - 3.2e-06 27.5 0.0 1.1e-05 25.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AIM23122.1 - 1.8e-05 25.2 0.5 6.7e-05 23.3 0.5 2.0 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 AIM23122.1 - 6.4e-05 22.5 0.0 0.013 15.0 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 AIM23122.1 - 0.00018 21.5 0.0 0.00044 20.2 0.0 1.6 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 AIM23122.1 - 0.00039 21.0 0.0 0.001 19.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 AIM23122.1 - 0.00059 19.5 0.0 0.0016 18.1 0.0 1.7 1 1 0 1 1 1 1 P-loop containing region of AAA domain Rad17 PF03215.15 AIM23122.1 - 0.0014 18.6 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 AIM23122.1 - 0.0017 18.1 0.1 0.02 14.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 AIM23122.1 - 0.0022 17.6 0.1 0.013 15.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 AIM23122.1 - 0.0076 16.2 0.1 0.49 10.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TniB PF05621.11 AIM23122.1 - 0.011 15.1 0.1 0.34 10.3 0.0 2.5 1 1 1 2 2 2 0 Bacterial TniB protein AAA_15 PF13175.6 AIM23122.1 - 0.022 14.5 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.17 AIM23122.1 - 0.026 14.3 0.1 3.6 7.3 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_33 PF13671.6 AIM23122.1 - 0.037 14.2 0.6 0.22 11.7 0.6 2.3 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 AIM23122.1 - 0.043 14.2 0.0 1.5 9.3 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 AIM23122.1 - 0.047 12.9 0.0 0.073 12.2 0.0 1.3 1 1 0 1 1 1 0 NB-ARC domain AAA_28 PF13521.6 AIM23122.1 - 0.067 13.4 0.2 0.76 10.0 0.0 2.5 2 1 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 AIM23122.1 - 0.078 11.8 0.0 6 5.5 0.0 2.3 2 0 0 2 2 2 0 Predicted ATPase of the ABC class NACHT PF05729.12 AIM23122.1 - 0.11 12.4 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain BPD_transp_1 PF00528.22 AIM23123.1 - 8.7e-18 64.7 16.0 8.7e-18 64.7 16.0 3.0 2 1 1 3 3 3 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 AIM23124.1 - 2.4e-12 46.9 32.3 4.5e-11 42.8 28.6 3.0 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component PP_kinase_C_1 PF17941.1 AIM23125.1 - 6.7e-75 250.2 0.1 1.1e-74 249.6 0.1 1.3 1 0 0 1 1 1 1 Polyphosphate kinase C-terminal domain 1 PP_kinase_C PF13090.6 AIM23125.1 - 1.1e-70 236.5 1.0 2.3e-68 229.0 0.1 2.3 2 0 0 2 2 2 2 Polyphosphate kinase C-terminal domain 2 PP_kinase PF02503.17 AIM23125.1 - 1.4e-45 155.3 0.5 2.7e-45 154.5 0.5 1.4 1 0 0 1 1 1 1 Polyphosphate kinase middle domain PP_kinase_N PF13089.6 AIM23125.1 - 9.9e-32 109.5 0.7 2.6e-31 108.1 0.7 1.8 1 0 0 1 1 1 1 Polyphosphate kinase N-terminal domain PLDc_2 PF13091.6 AIM23125.1 - 5e-17 62.0 0.8 2e-09 37.5 0.3 3.2 3 1 0 3 3 3 2 PLD-like domain MR_MLE_C PF13378.6 AIM23125.1 - 0.016 14.8 0.1 0.029 13.9 0.1 1.4 1 0 0 1 1 1 0 Enolase C-terminal domain-like Pyr_redox PF00070.27 AIM23125.1 - 0.12 13.0 0.1 0.57 10.8 0.1 2.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ppx-GppA PF02541.16 AIM23126.1 - 4.9e-98 328.1 0.0 7.5e-98 327.5 0.0 1.3 1 0 0 1 1 1 1 Ppx/GppA phosphatase family HD PF01966.22 AIM23126.1 - 0.009 16.2 0.1 0.019 15.2 0.1 1.6 1 0 0 1 1 1 1 HD domain FtsA PF14450.6 AIM23126.1 - 0.018 15.4 0.1 1.3 9.5 0.0 3.0 3 1 0 3 3 3 0 Cell division protein FtsA DUF2633 PF11119.8 AIM23127.1 - 2.9e-20 71.9 0.1 3.1e-20 71.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2633) Sigma_reg_N PF13800.6 AIM23127.1 - 0.05 13.9 0.0 0.05 13.9 0.0 1.0 1 0 0 1 1 1 0 Sigma factor regulator N-terminal MgtE PF01769.16 AIM23128.1 - 1e-24 87.3 11.6 1e-24 87.3 11.6 1.6 2 0 0 2 2 2 1 Divalent cation transporter MgtE_N PF03448.17 AIM23128.1 - 2.7e-22 79.3 3.0 2.7e-22 79.3 3.0 1.7 2 0 0 2 2 2 1 MgtE intracellular N domain CBS PF00571.28 AIM23128.1 - 4e-11 43.2 1.5 1.4e-06 28.6 0.0 3.2 3 0 0 3 3 3 2 CBS domain ABA_GPCR PF12430.8 AIM23128.1 - 0.23 11.2 1.2 0.4 10.4 1.2 1.3 1 0 0 1 1 1 0 Abscisic acid G-protein coupled receptor GGDEF PF00990.21 AIM23129.1 - 2.9e-41 140.9 0.0 4.7e-41 140.2 0.0 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_3 PF08447.12 AIM23129.1 - 2.7e-32 110.9 0.0 8.6e-16 58.0 0.0 3.5 4 0 0 4 4 4 2 PAS fold EAL PF00563.20 AIM23129.1 - 1.4e-27 96.7 1.2 2.9e-27 95.7 1.2 1.4 1 0 0 1 1 1 1 EAL domain PAS PF00989.25 AIM23129.1 - 4e-25 88.0 0.0 7.8e-11 42.0 0.0 3.9 3 1 0 3 3 3 3 PAS fold PAS_4 PF08448.10 AIM23129.1 - 8.3e-24 84.0 0.5 3.4e-08 33.7 0.0 3.8 3 0 0 3 3 3 3 PAS fold PAS_9 PF13426.7 AIM23129.1 - 1.6e-22 79.7 0.0 1e-10 41.8 0.0 3.4 3 0 0 3 3 3 3 PAS domain MASE1 PF05231.14 AIM23129.1 - 4.3e-17 62.2 43.3 7.5e-17 61.4 43.3 1.3 1 0 0 1 1 1 1 MASE1 PAS_8 PF13188.7 AIM23129.1 - 2e-11 43.6 0.0 0.00022 21.1 0.0 3.8 3 0 0 3 3 3 2 PAS domain PAS_7 PF12860.7 AIM23129.1 - 2.2e-07 31.0 0.0 0.0011 19.1 0.0 3.6 3 0 0 3 3 3 2 PAS fold PAS_10 PF13596.6 AIM23129.1 - 0.00068 20.2 0.0 0.017 15.7 0.0 2.7 1 1 1 2 2 2 1 PAS domain PAS_11 PF14598.6 AIM23129.1 - 0.012 15.7 0.0 8.3 6.6 0.0 2.6 2 0 0 2 2 2 0 PAS domain GGDEF_2 PF17853.1 AIM23129.1 - 0.03 14.6 2.4 0.27 11.5 0.1 3.4 3 1 0 3 3 3 0 GGDEF-like domain HTH_Tnp_Mu_1 PF02316.16 AIM23130.1 - 9e-09 35.6 0.0 2e-08 34.5 0.0 1.6 1 1 0 1 1 1 1 Mu DNA-binding domain DUF1323 PF07037.11 AIM23130.1 - 2e-06 28.2 0.2 1.8e-05 25.1 0.2 1.9 1 1 0 1 1 1 1 Putative transcription regulator (DUF1323) AlkA_N PF06029.11 AIM23131.1 - 1.8e-31 108.8 0.1 3.7e-31 107.8 0.1 1.5 1 0 0 1 1 1 1 AlkA N-terminal domain Ada_Zn_binding PF02805.16 AIM23131.1 - 5.8e-29 99.9 3.2 1.1e-28 99.1 3.2 1.5 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_18 PF12833.7 AIM23131.1 - 7.5e-24 83.8 0.9 2.8e-23 82.0 0.9 2.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AIM23131.1 - 9.7e-09 35.1 0.1 0.01 15.9 0.0 3.0 3 0 0 3 3 3 2 Bacterial regulatory helix-turn-helix proteins, AraC family HhH-GPD PF00730.25 AIM23131.1 - 6.1e-08 33.1 0.0 2.2e-07 31.3 0.0 2.0 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein DUF1952 PF09189.10 AIM23131.1 - 0.015 15.2 1.9 0.084 12.7 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1952) HTH_28 PF13518.6 AIM23131.1 - 0.12 12.5 3.4 0.2 11.8 0.1 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_23 PF13384.6 AIM23131.1 - 0.13 12.1 4.7 0.28 11.0 0.0 3.0 3 0 0 3 3 3 0 Homeodomain-like domain adh_short PF00106.25 AIM23132.1 - 5.3e-49 166.3 1.0 8.4e-49 165.7 1.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AIM23132.1 - 2.3e-35 122.2 4.5 3.1e-35 121.8 4.5 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AIM23132.1 - 5.3e-11 42.7 2.9 1.8e-10 41.0 0.6 2.1 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 AIM23132.1 - 1e-08 35.3 3.9 1.2e-08 35.0 3.6 1.3 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 AIM23132.1 - 1.9e-08 34.1 0.6 3.3e-08 33.3 0.6 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 AIM23132.1 - 9e-07 28.5 0.0 9.2e-06 25.2 0.0 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.13 AIM23132.1 - 0.00012 21.7 1.1 0.00019 21.1 1.1 1.2 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 AIM23132.1 - 0.00027 20.1 0.6 0.00053 19.2 0.6 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 AIM23132.1 - 0.021 14.2 0.3 0.038 13.4 0.3 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase ApbA PF02558.16 AIM23132.1 - 0.029 14.0 0.1 0.044 13.4 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Glyco_trans_4_2 PF13477.6 AIM23132.1 - 0.034 14.2 0.0 0.1 12.6 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase 4-like Eno-Rase_NADH_b PF12242.8 AIM23132.1 - 0.066 13.0 0.2 0.17 11.7 0.2 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_2 PF03446.15 AIM23132.1 - 0.1 12.7 0.9 0.25 11.5 0.1 1.9 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Arabinose_bd PF12625.7 AIM23133.1 - 5e-31 108.2 4.1 8.1e-31 107.6 4.1 1.3 1 0 0 1 1 1 1 Arabinose-binding domain of AraC transcription regulator, N-term HTH_18 PF12833.7 AIM23133.1 - 1.1e-17 64.0 2.0 2.6e-17 62.9 1.4 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 AIM23133.1 - 1.9e-06 27.8 0.0 0.022 14.9 0.0 2.5 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_8 PF02954.19 AIM23133.1 - 0.00019 21.1 0.2 0.00062 19.5 0.2 1.9 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family HTH_23 PF13384.6 AIM23133.1 - 0.022 14.6 0.0 0.067 13.0 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_AsnC-type PF13404.6 AIM23133.1 - 0.024 14.4 0.6 1.4 8.9 0.2 2.7 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_30 PF13556.6 AIM23133.1 - 0.027 14.3 0.0 0.13 12.1 0.0 2.1 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_28 PF13518.6 AIM23133.1 - 0.045 13.9 0.0 0.1 12.7 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain DUF3856 PF12968.7 AIM23133.1 - 0.051 13.7 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF3856) HSP70 PF00012.20 AIM23134.1 - 1.7e-22 79.4 0.0 1.4e-09 36.7 0.0 3.0 3 0 0 3 3 3 3 Hsp70 protein MreB_Mbl PF06723.13 AIM23134.1 - 3.1e-10 39.4 0.1 5.7e-07 28.7 0.0 2.6 3 0 0 3 3 3 2 MreB/Mbl protein StbA PF06406.11 AIM23134.1 - 0.00018 20.8 0.0 0.044 13.0 0.0 2.6 3 0 0 3 3 3 2 StbA protein AnmK PF03702.14 AIM23134.1 - 0.0043 16.2 0.0 0.0091 15.1 0.0 1.5 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase BcrAD_BadFG PF01869.20 AIM23134.1 - 0.0044 16.5 0.0 2.8 7.4 0.0 2.8 2 1 1 3 3 3 2 BadF/BadG/BcrA/BcrD ATPase family MutL PF13941.6 AIM23134.1 - 0.019 13.6 0.0 0.31 9.6 0.0 2.2 2 0 0 2 2 2 0 MutL protein FtsA PF14450.6 AIM23134.1 - 0.05 14.0 0.5 0.63 10.5 0.0 3.0 4 0 0 4 4 4 0 Cell division protein FtsA Ppx-GppA PF02541.16 AIM23134.1 - 0.091 12.2 1.1 0.17 11.3 0.2 1.7 2 0 0 2 2 2 0 Ppx/GppA phosphatase family PilM_2 PF11104.8 AIM23134.1 - 0.11 11.6 0.0 0.71 8.8 0.0 2.2 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; Acetyltransf_3 PF13302.7 AIM23135.1 - 3.8e-36 124.8 0.0 4.7e-36 124.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AIM23135.1 - 7.2e-07 29.5 0.0 9.4e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family RseA_C PF03873.13 AIM23135.1 - 0.031 14.5 0.2 0.083 13.1 0.1 1.7 2 0 0 2 2 2 0 Anti sigma-E protein RseA, C-terminal domain Acetyltransf_8 PF13523.6 AIM23135.1 - 0.033 13.9 0.2 0.079 12.6 0.2 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Trp_DMAT PF11991.8 AIM23135.1 - 0.14 11.6 0.0 0.19 11.1 0.0 1.1 1 0 0 1 1 1 0 Tryptophan dimethylallyltransferase Putative_PNPOx PF01243.20 AIM23136.1 - 6.2e-16 58.4 0.0 8.5e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Aldo_ket_red PF00248.21 AIM23137.1 - 1.3e-72 244.5 0.0 1.5e-72 244.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PrkA PF06798.12 AIM23137.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 PrkA serine protein kinase C-terminal domain Biotin_lipoyl_2 PF13533.6 AIM23138.1 - 2.1e-17 62.7 1.0 8.3e-16 57.6 0.3 2.9 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_D23 PF16576.5 AIM23138.1 - 2.4e-13 49.8 1.7 4.3e-13 49.0 1.7 1.4 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AIM23138.1 - 2.9e-13 50.5 1.1 4e-07 30.7 0.1 2.6 2 0 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl PF00364.22 AIM23138.1 - 5.2e-05 23.0 0.3 0.0014 18.4 0.0 2.6 2 0 0 2 2 2 1 Biotin-requiring enzyme PTS_EIIA_1 PF00358.20 AIM23138.1 - 0.0019 18.0 0.1 0.036 13.8 0.0 2.5 2 0 0 2 2 2 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 BMFP PF04380.13 AIM23138.1 - 0.015 15.8 0.5 0.034 14.6 0.5 1.5 1 0 0 1 1 1 0 Membrane fusogenic activity VWA_3_C PF18571.1 AIM23138.1 - 0.035 14.0 0.0 0.1 12.5 0.0 1.8 1 0 0 1 1 1 0 von Willebrand factor type A C-terminal domain Peptidase_M23 PF01551.22 AIM23138.1 - 0.072 13.3 1.1 3.6 7.9 0.0 2.8 3 0 0 3 3 3 0 Peptidase family M23 DUF2543 PF10820.8 AIM23138.1 - 0.17 12.0 0.2 0.42 10.8 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2543) FliJ PF02050.16 AIM23138.1 - 0.45 10.7 8.0 0.79 10.0 8.0 1.3 1 0 0 1 1 1 0 Flagellar FliJ protein ACR_tran PF00873.19 AIM23139.1 - 0 1188.1 32.9 0 1187.9 32.9 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family SecD_SecF PF02355.16 AIM23139.1 - 9.3e-08 31.7 29.5 4.8e-06 26.1 14.2 2.6 2 0 0 2 2 2 2 Protein export membrane protein Man-6-P_recep PF02157.15 AIM23139.1 - 0.076 12.1 0.3 0.16 11.0 0.3 1.5 1 0 0 1 1 1 0 Mannose-6-phosphate receptor DUF883 PF05957.13 AIM23139.1 - 1 10.0 6.2 4.5 8.0 0.0 4.1 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) ACR_tran PF00873.19 AIM23140.1 - 0 1167.3 14.0 0 1167.1 14.0 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AIM23140.1 - 2.5e-14 53.0 21.6 5.1e-08 32.2 9.3 2.5 2 0 0 2 2 2 2 MMPL family SecD_SecF PF02355.16 AIM23140.1 - 1.9e-05 24.2 22.0 0.0007 19.0 8.7 2.5 2 0 0 2 2 2 2 Protein export membrane protein MFS_1 PF07690.16 AIM23141.1 - 5.5e-53 180.1 72.1 5.7e-47 160.4 53.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 AIM23141.1 - 4.8e-09 35.1 27.7 2.1e-07 29.7 13.2 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector HATPase_c PF02518.26 AIM23142.1 - 1.2e-21 77.3 0.0 2.7e-21 76.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 AIM23142.1 - 2.6e-16 59.7 1.8 9.4e-16 57.9 0.2 2.8 3 0 0 3 3 3 1 HAMP domain HisKA PF00512.25 AIM23142.1 - 5.8e-14 51.9 2.2 2e-13 50.1 0.4 2.7 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain Baculo_PEP_C PF04513.12 AIM23142.1 - 0.043 13.8 0.2 0.1 12.6 0.2 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FUSC PF04632.12 AIM23142.1 - 0.055 12.0 6.6 0.077 11.5 6.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family FlgN PF05130.12 AIM23142.1 - 5 7.6 5.6 0.51 10.8 0.4 2.0 3 0 0 3 3 3 0 FlgN protein Response_reg PF00072.24 AIM23143.1 - 3.2e-25 88.5 0.0 4.6e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AIM23143.1 - 3.6e-23 81.4 0.1 6.4e-23 80.6 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal MarR_2 PF12802.7 AIM23143.1 - 0.14 12.1 0.0 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 MarR family DUF1508 PF07411.12 AIM23145.1 - 2e-46 155.6 2.0 8.2e-23 80.0 0.5 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF1508) LCCL PF03815.19 AIM23145.1 - 0.13 12.4 1.0 5.2 7.2 0.1 2.2 2 0 0 2 2 2 0 LCCL domain Peptidase_U32 PF01136.19 AIM23146.1 - 1.9e-95 318.4 0.0 2.7e-95 318.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family U32 Peptidase_U32_C PF16325.5 AIM23146.1 - 1.7e-23 82.7 0.0 3.7e-23 81.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase family U32 C-terminal domain Tachystatin_B PF11478.8 AIM23146.1 - 0.38 10.7 4.0 0.15 12.0 0.6 2.0 2 0 0 2 2 2 0 Antimicrobial chitin binding protein tachystatin B DAGK_cat PF00781.24 AIM23147.1 - 1.8e-30 105.1 0.2 2.7e-30 104.6 0.2 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 AIM23147.1 - 0.029 13.6 0.0 0.044 13.0 0.0 1.2 1 0 0 1 1 1 0 ATP-NAD kinase DeoC PF01791.9 AIM23148.1 - 5.8e-73 245.4 0.0 6.9e-73 245.1 0.0 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase ATP-cone PF03477.16 AIM23149.1 - 0.14 12.7 4.7 3.7 8.2 0.1 2.4 1 1 1 2 2 2 0 ATP cone domain HTH_7 PF02796.15 AIM23149.1 - 0.17 12.0 0.7 6 7.0 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase EII-GUT PF03608.13 AIM23150.1 - 4.2e-76 254.5 0.6 4.8e-76 254.3 0.6 1.0 1 0 0 1 1 1 1 PTS system enzyme II sorbitol-specific factor EIIBC-GUT_N PF03612.14 AIM23151.1 - 2.1e-69 233.0 0.0 2.7e-69 232.6 0.0 1.1 1 0 0 1 1 1 1 Sorbitol phosphotransferase enzyme II N-terminus EIIBC-GUT_C PF07663.11 AIM23151.1 - 1.3e-41 140.7 4.8 1.3e-41 140.7 4.8 2.1 2 0 0 2 2 2 1 Sorbitol phosphotransferase enzyme II C-terminus Gate PF07670.14 AIM23151.1 - 0.0037 17.5 2.4 0.0037 17.5 2.4 1.6 2 0 0 2 2 2 1 Nucleoside recognition PTSIIA_gutA PF03829.13 AIM23152.1 - 5.1e-38 129.4 0.0 5.7e-38 129.3 0.0 1.0 1 0 0 1 1 1 1 PTS system glucitol/sorbitol-specific IIA component adh_short PF00106.25 AIM23153.1 - 2.7e-46 157.5 0.1 3.1e-46 157.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AIM23153.1 - 4.2e-42 144.3 0.0 7.2e-42 143.5 0.0 1.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AIM23153.1 - 3.7e-05 23.7 0.6 6.1e-05 23.0 0.6 1.4 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 AIM23153.1 - 0.0029 17.5 0.5 0.0043 17.0 0.5 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 AIM23153.1 - 0.017 15.7 0.7 0.094 13.3 0.8 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 AIM23153.1 - 0.018 14.5 0.1 1 8.7 0.1 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family GutM PF06923.11 AIM23154.1 - 7.7e-32 109.6 0.0 8.7e-32 109.4 0.0 1.0 1 0 0 1 1 1 1 Glucitol operon activator protein (GutM) DeoRC PF00455.22 AIM23155.1 - 1.6e-52 177.7 0.6 2.4e-52 177.1 0.6 1.3 1 0 0 1 1 1 1 DeoR C terminal sensor domain HTH_DeoR PF08220.12 AIM23155.1 - 5.5e-18 64.5 0.3 1.2e-17 63.4 0.3 1.6 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 AIM23155.1 - 2e-07 30.8 0.1 1.5e-06 28.1 0.0 2.1 2 0 0 2 2 2 1 HTH domain FeoC PF09012.10 AIM23155.1 - 0.005 16.9 0.0 0.0092 16.0 0.0 1.4 1 0 0 1 1 1 1 FeoC like transcriptional regulator GntR PF00392.21 AIM23155.1 - 0.032 13.9 0.0 0.072 12.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family DprA_WH PF17782.1 AIM23155.1 - 0.047 13.8 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 DprA winged helix domain HTH_Mga PF08280.11 AIM23155.1 - 0.049 13.7 0.0 0.094 12.8 0.0 1.4 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain HTH_AsnC-type PF13404.6 AIM23155.1 - 0.09 12.6 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_5 PF01022.20 AIM23155.1 - 0.094 12.6 0.1 0.77 9.7 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_28 PF13518.6 AIM23155.1 - 0.11 12.7 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Put_DNA-bind_N PF06971.13 AIM23155.1 - 0.12 12.4 0.0 0.78 9.8 0.0 2.2 2 0 0 2 2 2 0 Putative DNA-binding protein N-terminus TubC_N PF18563.1 AIM23155.1 - 0.19 11.8 0.5 13 5.8 0.2 3.1 3 0 0 3 3 3 0 TubC N-terminal docking domain SIS PF01380.22 AIM23156.1 - 2.6e-33 114.7 0.0 4.4e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 SIS domain CBS PF00571.28 AIM23156.1 - 8.3e-12 45.4 0.0 4.1e-05 23.9 0.0 2.6 2 0 0 2 2 2 2 CBS domain Ivy PF08816.11 AIM23157.1 - 1.5e-40 138.1 0.2 1.6e-40 137.9 0.2 1.0 1 0 0 1 1 1 1 Inhibitor of vertebrate lysozyme (Ivy) Phos_pyr_kin PF08543.12 AIM23158.1 - 6.3e-94 314.0 0.0 7.1e-94 313.8 0.0 1.0 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 AIM23158.1 - 9.5e-06 25.1 0.1 1.2e-05 24.7 0.1 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Carb_kinase PF01256.17 AIM23158.1 - 0.0062 16.0 0.2 0.0095 15.4 0.2 1.4 1 1 0 1 1 1 1 Carbohydrate kinase HK PF02110.15 AIM23159.1 - 1.1e-88 296.8 0.3 1.2e-88 296.6 0.3 1.0 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Carb_kinase PF01256.17 AIM23159.1 - 4.9e-05 22.9 0.3 5.6e-05 22.7 0.3 1.2 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 AIM23159.1 - 0.00037 20.0 0.1 0.0006 19.3 0.1 1.4 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase Acetyltransf_7 PF13508.7 AIM23160.1 - 9.7e-13 48.4 0.0 1.3e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AIM23160.1 - 3.1e-12 46.5 0.0 3.8e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AIM23160.1 - 1.2e-10 41.7 0.0 1.4e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 AIM23160.1 - 0.12 12.6 0.0 6.1 7.0 0.0 2.2 1 1 1 2 2 2 0 GCN5-related N-acetyl-transferase MFS_1 PF07690.16 AIM23161.1 - 3.3e-34 118.4 63.5 2.2e-27 95.9 39.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AIM23161.1 - 2.9e-09 36.3 9.0 2.9e-09 36.3 9.0 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.20 AIM23161.1 - 0.018 13.3 0.0 0.018 13.3 0.0 2.2 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family HxlR PF01638.17 AIM23162.1 - 2.7e-19 68.8 0.0 4.4e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 HxlR-like helix-turn-helix DUF1158 PF06643.11 AIM23163.1 - 4.3e-07 30.4 2.9 4.6e-07 30.2 2.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1158) Phage_holin_3_6 PF07332.11 AIM23163.1 - 0.0074 16.3 3.3 0.0082 16.2 3.3 1.1 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III PseudoU_synth_2 PF00849.22 AIM23166.1 - 1.9e-15 57.3 0.1 9.8e-15 55.0 0.1 2.0 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 AIM23166.1 - 1.1e-10 41.0 1.7 2.5e-10 39.9 0.1 2.4 2 1 1 3 3 3 1 S4 domain S4_2 PF13275.6 AIM23166.1 - 0.00023 20.9 0.1 0.00055 19.7 0.1 1.7 1 0 0 1 1 1 1 S4 domain DUF943 PF06092.12 AIM23167.1 - 2e-29 102.2 0.2 2.4e-29 102.0 0.2 1.0 1 0 0 1 1 1 1 Enterobacterial putative membrane protein (DUF943) Ge1_WD40 PF16529.5 AIM23167.1 - 0.022 13.7 0.0 0.028 13.4 0.0 1.1 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Gemini_mov PF01708.16 AIM23167.1 - 0.041 13.6 0.6 0.075 12.8 0.6 1.3 1 0 0 1 1 1 0 Geminivirus putative movement protein BRX PF08381.11 AIM23167.1 - 0.089 12.2 2.9 0.13 11.6 1.6 1.9 2 0 0 2 2 2 0 Transcription factor regulating root and shoot growth via Pin3 DUF3289 PF11692.8 AIM23168.1 - 2.3e-72 243.9 3.2 2.6e-72 243.7 3.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3289) Autotransporter PF03797.19 AIM23169.1 - 4.7e-65 219.8 21.2 4.7e-65 219.8 21.2 2.8 2 1 1 3 3 3 1 Autotransporter beta-domain LPAM_1 PF08139.12 AIM23171.1 - 0.052 14.1 1.3 0.091 13.3 1.3 1.4 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site GerE PF00196.19 AIM23172.1 - 1.7e-20 72.3 0.1 3.6e-20 71.3 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Response_reg PF00072.24 AIM23172.1 - 2.5e-14 53.4 0.0 4.6e-14 52.5 0.0 1.5 2 0 0 2 2 2 1 Response regulator receiver domain Sigma70_r4_2 PF08281.12 AIM23172.1 - 6.3e-06 25.8 0.0 1.1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_10 PF04967.12 AIM23172.1 - 0.0015 18.3 0.1 0.0078 16.0 0.0 2.1 2 0 0 2 2 2 1 HTH DNA binding domain DUF2089 PF09862.9 AIM23172.1 - 0.0025 17.8 0.0 0.0043 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2089) HTH_24 PF13412.6 AIM23172.1 - 0.0056 16.2 0.0 0.015 14.8 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.16 AIM23172.1 - 0.01 15.4 0.0 0.021 14.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_23 PF13384.6 AIM23172.1 - 0.017 14.9 0.0 0.071 12.9 0.0 2.1 2 1 0 2 2 2 0 Homeodomain-like domain Sigma70_ECF PF07638.11 AIM23172.1 - 0.019 14.9 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 ECF sigma factor HTH_40 PF14493.6 AIM23172.1 - 0.039 14.4 0.0 0.1 13.1 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Imm1 PF14430.6 AIM23172.1 - 0.041 14.5 0.0 0.057 14.1 0.0 1.3 1 0 0 1 1 1 0 Immunity protein Imm1 RepB PF07506.11 AIM23172.1 - 0.1 12.7 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 RepB plasmid partitioning protein HATPase_c PF02518.26 AIM23173.1 - 3.6e-17 62.9 0.0 7.2e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AIM23173.1 - 4.3e-10 39.5 2.4 2.6e-09 37.0 0.3 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 AIM23173.1 - 1.8e-09 37.8 0.0 3.3e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c_2 PF13581.6 AIM23173.1 - 0.037 14.0 0.0 0.085 12.8 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain EMC3_TMCO1 PF01956.16 AIM23173.1 - 0.14 11.8 2.4 0.13 12.0 0.5 1.8 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like ABC_membrane PF00664.23 AIM23174.1 - 1.6e-44 152.6 19.0 2.2e-44 152.2 19.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region Peptidase_C39 PF03412.15 AIM23174.1 - 6.4e-35 119.9 0.0 1.2e-34 119.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase C39 family ABC_tran PF00005.27 AIM23174.1 - 1.1e-16 61.6 0.0 1.8e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter Peptidase_C70 PF12385.8 AIM23174.1 - 4.6e-06 26.7 0.0 1.1e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Papain-like cysteine protease AvrRpt2 AAA_29 PF13555.6 AIM23174.1 - 0.0051 16.5 0.1 0.016 14.9 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AIM23174.1 - 0.0058 17.0 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AIM23174.1 - 0.0097 16.2 0.1 0.045 14.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 AIM23174.1 - 0.01 15.7 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase DLIC PF05783.11 AIM23174.1 - 0.022 13.6 0.0 0.045 12.6 0.0 1.5 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_14 PF13173.6 AIM23174.1 - 0.022 14.8 0.0 0.12 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 AIM23174.1 - 0.025 14.3 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AIM23174.1 - 0.027 15.0 0.1 0.045 14.3 0.1 1.2 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 AIM23174.1 - 0.049 13.0 0.8 0.071 12.5 0.1 1.5 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.23 AIM23174.1 - 0.052 13.6 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA PF00004.29 AIM23174.1 - 0.054 13.9 0.0 0.17 12.3 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 AIM23174.1 - 0.066 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 AIM23174.1 - 0.078 13.0 0.1 0.25 11.4 0.1 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 AIM23174.1 - 0.094 12.6 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 NTPase DUF3987 PF13148.6 AIM23174.1 - 0.1 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) AAA_7 PF12775.7 AIM23174.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 AIM23174.1 - 0.13 12.8 0.0 0.37 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AIM23174.1 - 0.16 11.6 0.1 0.29 10.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain Peptidase_C39_2 PF13529.6 AIM23174.1 - 0.19 12.3 0.2 0.5 10.9 0.0 1.7 2 0 0 2 2 1 0 Peptidase_C39 like family RNA_helicase PF00910.22 AIM23174.1 - 0.19 12.1 0.0 0.42 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase HlyD_3 PF13437.6 AIM23175.1 - 5.1e-15 56.1 0.8 5.3e-12 46.4 0.0 2.9 2 2 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AIM23175.1 - 7.5e-14 51.3 6.1 3.9e-06 26.6 0.0 3.7 3 1 0 3 3 3 2 Biotin-lipoyl like HlyD_D23 PF16576.5 AIM23175.1 - 5.4e-13 48.7 1.3 2.4e-10 40.0 1.3 2.3 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD PF00529.20 AIM23175.1 - 1.2e-08 34.7 0.0 4.2e-08 33.0 0.0 1.9 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl PF00364.22 AIM23175.1 - 7.5e-08 32.1 0.5 0.0071 16.2 0.0 3.1 3 0 0 3 3 3 2 Biotin-requiring enzyme RnfC_N PF13375.6 AIM23175.1 - 0.0021 18.0 0.7 0.041 13.8 0.2 2.8 2 1 1 3 3 3 1 RnfC Barrel sandwich hybrid domain PTS_EIIA_1 PF00358.20 AIM23175.1 - 0.0062 16.3 0.0 0.076 12.8 0.0 2.4 2 0 0 2 2 2 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Osmo_CC PF08946.10 AIM23175.1 - 0.025 14.8 1.4 0.22 11.8 0.2 2.4 2 0 0 2 2 2 0 Osmosensory transporter coiled coil MCM2_N PF12619.8 AIM23175.1 - 0.036 14.4 0.4 0.057 13.7 0.4 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance protein 2 MLD PF11647.8 AIM23175.1 - 0.7 10.2 3.6 0.35 11.2 0.3 2.2 2 0 0 2 2 2 0 Membrane Localization Domain YlqD PF11068.8 AIM23175.1 - 7.2 7.0 14.8 12 6.2 2.5 2.5 1 1 1 2 2 2 0 YlqD protein MccV PF17508.2 AIM23176.1 - 0.47 11.0 3.2 4.6 7.8 3.2 2.1 1 1 0 1 1 1 0 Microcin V bacteriocin Chol_subst-bind PF09129.11 AIM23177.1 - 1e-144 481.4 2.1 1.3e-144 481.0 2.1 1.1 1 0 0 1 1 1 1 Cholesterol oxidase, substrate-binding FAD_binding_4 PF01565.23 AIM23177.1 - 4.7e-16 58.8 0.0 9.1e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.14 AIM23177.1 - 1e-05 25.5 0.1 2e-05 24.5 0.1 1.5 1 1 0 1 1 1 1 D-arabinono-1,4-lactone oxidase HTH_18 PF12833.7 AIM23178.1 - 1.9e-23 82.5 0.7 2.9e-23 81.9 0.7 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AIM23178.1 - 1e-18 66.9 1.1 7.8e-10 38.6 0.1 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Cass2 PF14526.6 AIM23178.1 - 0.007 16.5 0.1 0.021 15.0 0.1 1.8 2 0 0 2 2 2 1 Integron-associated effector binding protein GyrI-like PF06445.15 AIM23178.1 - 0.089 13.1 0.0 0.18 12.1 0.0 1.6 1 1 0 1 1 1 0 GyrI-like small molecule binding domain GMP_synt_C PF00958.22 AIM23179.1 - 5.8e-44 148.1 0.0 1.2e-43 147.1 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 AIM23179.1 - 2.7e-40 138.2 0.0 4.1e-40 137.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 AIM23179.1 - 4.2e-09 35.9 0.1 1.2e-06 27.8 0.0 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 AIM23179.1 - 9.1e-09 35.4 0.1 2.4e-08 34.0 0.1 1.7 1 1 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 AIM23179.1 - 6.4e-05 21.9 0.1 0.00033 19.6 0.0 1.9 2 0 0 2 2 2 1 tRNA methyl transferase Asn_synthase PF00733.21 AIM23179.1 - 0.0092 15.7 0.0 0.054 13.1 0.0 1.9 2 0 0 2 2 2 1 Asparagine synthase QueC PF06508.13 AIM23179.1 - 0.0095 15.4 0.1 2.1 7.8 0.0 2.6 3 0 0 3 3 3 2 Queuosine biosynthesis protein QueC ThiI PF02568.14 AIM23179.1 - 0.012 15.2 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) ATP_bind_3 PF01171.20 AIM23179.1 - 0.044 13.5 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 PP-loop family PAPS_reduct PF01507.19 AIM23179.1 - 0.09 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family IMPDH PF00478.25 AIM23180.1 - 9.1e-160 531.3 11.3 1e-159 531.1 11.3 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 AIM23180.1 - 4.9e-17 62.1 3.1 1.3e-08 35.1 0.1 3.6 3 0 0 3 3 3 2 CBS domain FMN_dh PF01070.18 AIM23180.1 - 1.3e-09 37.6 8.7 1e-08 34.6 5.9 2.3 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 AIM23180.1 - 5.9e-09 35.8 17.0 5e-05 22.8 10.9 2.7 1 1 2 3 3 3 2 Nitronate monooxygenase His_biosynth PF00977.21 AIM23180.1 - 0.0004 19.9 4.7 0.0043 16.5 0.2 2.7 1 1 0 1 1 1 1 Histidine biosynthesis protein TMP-TENI PF02581.17 AIM23180.1 - 0.002 17.5 7.1 0.0025 17.2 3.6 2.3 1 1 0 2 2 2 1 Thiamine monophosphate synthase NanE PF04131.14 AIM23180.1 - 0.0031 16.7 6.1 0.026 13.7 6.1 2.8 1 1 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase Glu_synthase PF01645.17 AIM23180.1 - 0.005 16.0 6.7 0.005 16.0 6.7 1.6 2 0 0 2 2 2 1 Conserved region in glutamate synthase DHO_dh PF01180.21 AIM23180.1 - 0.0068 15.7 2.7 0.0068 15.7 2.7 2.1 1 1 1 2 2 2 1 Dihydroorotate dehydrogenase Radical_SAM PF04055.21 AIM23180.1 - 0.11 12.9 0.0 0.6 10.5 0.0 2.2 1 1 0 1 1 1 0 Radical SAM superfamily ThiG PF05690.14 AIM23180.1 - 0.16 11.2 13.4 0.049 12.9 6.7 3.1 3 1 0 3 3 3 0 Thiazole biosynthesis protein ThiG G3P_antiterm PF04309.12 AIM23180.1 - 0.36 10.2 2.9 0.8 9.1 0.3 2.5 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator Exonuc_VII_L PF02601.15 AIM23181.1 - 1.4e-101 340.1 6.5 2.2e-101 339.5 6.5 1.3 1 0 0 1 1 1 1 Exonuclease VII, large subunit tRNA_anti_2 PF13742.6 AIM23181.1 - 2.8e-34 117.2 0.4 1.9e-32 111.3 0.0 2.8 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain tRNA_anti-codon PF01336.25 AIM23181.1 - 2.1e-06 27.6 0.0 4.9e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain MFS_1 PF07690.16 AIM23182.1 - 5.6e-57 193.3 54.7 1.9e-53 181.6 34.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily AlaE PF06610.13 AIM23182.1 - 0.44 10.6 7.8 0.35 10.9 1.0 2.4 2 1 0 2 2 2 0 L-alanine exporter Peripla_BP_3 PF13377.6 AIM23183.1 - 1.4e-27 97.0 0.2 3.3e-27 95.8 0.2 1.6 1 0 0 1 1 1 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 AIM23183.1 - 6.8e-19 68.4 0.0 1.2e-18 67.5 0.0 1.3 1 1 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 AIM23183.1 - 1.2e-08 34.6 0.2 2.4e-08 33.7 0.2 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 AIM23183.1 - 3.5e-05 23.5 0.0 7.9e-05 22.4 0.0 1.6 2 0 0 2 2 2 1 Periplasmic binding protein domain HTH_IclR PF09339.10 AIM23183.1 - 5.3e-05 22.9 0.4 0.00029 20.6 0.0 2.3 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_24 PF13412.6 AIM23183.1 - 0.00012 21.5 0.2 0.0015 18.0 0.1 2.4 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_3 PF01381.22 AIM23183.1 - 0.0023 17.9 0.2 0.0053 16.8 0.2 1.6 1 0 0 1 1 1 1 Helix-turn-helix Crp PF00325.20 AIM23183.1 - 0.011 15.4 0.1 0.028 14.1 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family HTH_31 PF13560.6 AIM23183.1 - 0.012 15.9 0.1 0.03 14.7 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 AIM23183.1 - 0.018 14.5 0.1 0.051 13.0 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 AIM23183.1 - 0.027 14.3 0.0 0.1 12.4 0.0 2.0 1 0 0 1 1 1 0 Homeodomain-like domain HTH_7 PF02796.15 AIM23183.1 - 0.031 14.3 0.0 0.059 13.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Sigma70_r4_2 PF08281.12 AIM23183.1 - 0.034 13.8 0.0 0.13 12.0 0.0 2.0 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_AsnC-type PF13404.6 AIM23183.1 - 0.036 13.9 0.0 0.16 11.8 0.0 2.1 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_5 PF01022.20 AIM23183.1 - 0.048 13.5 0.4 0.17 11.8 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 AIM23183.1 - 0.059 13.3 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 MarR family MarR PF01047.22 AIM23183.1 - 0.063 13.2 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_Crp_2 PF13545.6 AIM23183.1 - 0.069 13.1 0.1 0.39 10.7 0.0 2.3 2 0 0 2 2 1 0 Crp-like helix-turn-helix domain Sigma54_DBD PF04552.13 AIM23183.1 - 0.1 12.3 0.1 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 Sigma-54, DNA binding domain RepL PF05732.11 AIM23183.1 - 0.11 11.9 0.2 0.42 10.0 0.2 1.8 1 1 0 1 1 1 0 Firmicute plasmid replication protein (RepL) Peptidase_M4_C PF02868.15 AIM23184.1 - 3.3e-50 170.2 0.1 9.3e-50 168.8 0.0 1.7 2 0 0 2 2 2 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.18 AIM23184.1 - 2.2e-31 109.3 0.1 3.5e-31 108.7 0.1 1.3 1 0 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain PLN_propep PF16485.5 AIM23184.1 - 8.7e-17 60.6 0.3 2.1e-16 59.4 0.3 1.6 1 0 0 1 1 1 1 Protealysin propeptide zinc-ribbons_6 PF07191.12 AIM23185.1 - 2.7e-29 101.0 7.8 3e-29 100.8 7.8 1.0 1 0 0 1 1 1 1 zinc-ribbons DZR PF12773.7 AIM23185.1 - 0.00048 20.1 11.2 0.025 14.6 2.7 2.1 1 1 1 2 2 2 2 Double zinc ribbon zf-C3HC4_3 PF13920.6 AIM23185.1 - 0.0045 16.8 9.7 0.019 14.8 2.3 2.4 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Zn-ribbon_8 PF09723.10 AIM23185.1 - 0.0064 16.6 13.6 0.023 14.8 4.6 3.4 3 2 0 3 3 3 1 Zinc ribbon domain DiS_P_DiS PF06750.13 AIM23185.1 - 0.019 15.1 9.5 0.56 10.4 3.1 2.8 1 1 2 3 3 3 0 Bacterial Peptidase A24 N-terminal domain DNA_ligase_ZBD PF03119.16 AIM23185.1 - 0.024 14.7 1.2 0.024 14.7 1.2 2.6 3 0 0 3 3 2 0 NAD-dependent DNA ligase C4 zinc finger domain Auto_anti-p27 PF06677.12 AIM23185.1 - 0.078 13.1 10.8 0.26 11.5 0.7 2.5 2 1 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-ribbon_3 PF13248.6 AIM23185.1 - 0.13 11.7 14.6 0.12 11.8 1.7 3.7 3 1 0 3 3 3 0 zinc-ribbon domain DUF2256 PF10013.9 AIM23185.1 - 0.19 11.9 7.1 14 5.9 0.2 3.2 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) YhfH PF14149.6 AIM23185.1 - 0.23 11.5 0.3 0.23 11.5 0.3 2.5 2 1 0 2 2 2 0 YhfH-like protein zf-HYPF PF07503.12 AIM23185.1 - 0.23 11.3 9.1 19 5.2 5.0 3.5 2 1 0 2 2 2 0 HypF finger Nudix_N_2 PF14803.6 AIM23185.1 - 0.46 10.4 11.6 1.7 8.6 0.1 4.0 3 1 1 4 4 4 0 Nudix N-terminal PolC_DP2 PF03833.13 AIM23185.1 - 0.64 7.8 3.9 0.59 7.9 3.9 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 HypA PF01155.19 AIM23185.1 - 0.68 10.0 9.5 2.9 8.0 8.5 2.1 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_ribbon_recom PF13408.6 AIM23185.1 - 0.81 10.3 9.6 0.79 10.3 0.2 2.6 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain zf-TFIIB PF13453.6 AIM23185.1 - 0.95 8.8 14.3 0.52 9.7 1.4 3.0 2 1 1 3 3 3 0 Transcription factor zinc-finger DUF2396 PF09654.10 AIM23185.1 - 1.1 9.4 5.9 8.9 6.4 1.2 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2396) Rhodanese_C PF12368.8 AIM23185.1 - 1.2 9.6 10.0 1.7 9.1 0.7 2.0 1 1 1 2 2 2 0 Rhodanase C-terminal DpnI PF06044.12 AIM23185.1 - 1.3 8.6 6.4 2.2 7.9 0.3 2.2 1 1 1 2 2 2 0 Dam-replacing family zf-C4_Topoisom PF01396.19 AIM23185.1 - 1.8 8.4 9.3 1.9 8.3 1.6 2.7 2 1 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger YacG PF03884.14 AIM23185.1 - 3.3 7.5 8.8 4.4 7.1 1.9 2.5 2 1 0 2 2 2 0 DNA gyrase inhibitor YacG Zn_ribbon_SprT PF17283.2 AIM23185.1 - 4.7 7.2 14.3 8.4 6.4 0.2 3.7 3 1 1 4 4 4 0 SprT-like zinc ribbon domain FYVE PF01363.21 AIM23185.1 - 4.7 7.4 11.2 36 4.6 11.2 2.3 1 1 0 1 1 1 0 FYVE zinc finger PADR1 PF08063.12 AIM23185.1 - 6.6 6.6 11.3 10 6.0 2.2 2.3 1 1 1 2 2 2 0 PADR1 (NUC008) domain Mem_trans PF03547.18 AIM23186.1 - 3.4e-18 65.2 20.9 1.1e-09 37.2 11.1 2.0 1 1 0 2 2 2 2 Membrane transport protein SBF PF01758.16 AIM23186.1 - 2.5e-08 33.8 6.3 2.5e-08 33.8 6.3 2.7 2 1 1 3 3 3 1 Sodium Bile acid symporter family MMR_HSR1 PF01926.23 AIM23187.1 - 2e-54 182.5 0.3 1.5e-27 95.9 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 AIM23187.1 - 9e-32 109.8 0.0 2.4e-16 59.7 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B KH_dom-like PF14714.6 AIM23187.1 - 7.1e-26 90.3 0.0 1.3e-25 89.5 0.0 1.5 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal GTP_EFTU PF00009.27 AIM23187.1 - 2.4e-19 69.6 0.8 5.2e-09 35.9 0.1 4.9 3 2 1 4 4 4 3 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 AIM23187.1 - 1.4e-12 48.0 0.0 0.029 14.4 0.0 4.4 3 1 1 4 4 4 3 Dynamin family AIG1 PF04548.16 AIM23187.1 - 4.3e-09 36.0 0.1 2.2e-05 23.9 0.1 2.3 2 0 0 2 2 2 2 AIG1 family RsgA_GTPase PF03193.16 AIM23187.1 - 1.1e-07 31.9 0.0 0.12 12.3 0.0 3.9 3 1 1 4 4 4 2 RsgA GTPase Roc PF08477.13 AIM23187.1 - 7.6e-06 26.1 0.0 0.27 11.5 0.0 3.4 2 2 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 AIM23187.1 - 1.8e-05 24.4 1.2 1.5 8.3 0.1 4.3 3 2 2 5 5 5 2 CobW/HypB/UreG, nucleotide-binding domain Ras PF00071.22 AIM23187.1 - 4.6e-05 23.1 0.0 0.26 10.9 0.0 2.7 2 2 0 2 2 2 2 Ras family AAA_22 PF13401.6 AIM23187.1 - 0.00012 22.3 0.1 1.4 9.2 0.0 3.5 4 1 0 4 4 4 2 AAA domain ABC_tran PF00005.27 AIM23187.1 - 0.00014 22.4 0.0 0.46 11.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_24 PF13479.6 AIM23187.1 - 0.00015 21.5 0.0 0.21 11.3 0.0 2.7 2 1 0 3 3 2 2 AAA domain PduV-EutP PF10662.9 AIM23187.1 - 0.00034 20.4 0.0 5.7 6.7 0.0 3.9 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 AIM23187.1 - 0.00073 19.0 0.0 0.39 10.1 0.0 2.4 2 0 0 2 2 2 1 Bacterial TniB protein MeaB PF03308.16 AIM23187.1 - 0.0009 18.3 1.0 6 5.8 0.0 4.1 4 1 0 4 4 4 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 AIM23187.1 - 0.0016 17.7 0.0 0.93 8.6 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain SRP54 PF00448.22 AIM23187.1 - 0.0025 17.5 0.3 0.84 9.2 0.1 2.9 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain SRPRB PF09439.10 AIM23187.1 - 0.0025 17.2 0.0 0.33 10.4 0.0 2.5 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit RNA_helicase PF00910.22 AIM23187.1 - 0.0029 18.0 0.0 3.8 7.9 0.0 2.8 3 0 0 3 3 2 1 RNA helicase ATP_bind_1 PF03029.17 AIM23187.1 - 0.003 17.4 0.0 0.26 11.0 0.0 3.2 2 1 1 3 3 3 1 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 AIM23187.1 - 0.005 16.8 0.1 3.5 7.5 0.1 2.8 2 1 0 2 2 2 1 NTPase AAA_18 PF13238.6 AIM23187.1 - 0.019 15.5 0.0 9.7 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 AIM23187.1 - 0.032 14.4 0.0 9.3 6.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 AIM23187.1 - 0.032 13.8 0.1 24 4.4 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 AIM23187.1 - 0.037 14.4 1.3 31 4.9 0.0 3.8 2 1 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 AIM23187.1 - 0.042 13.6 0.0 13 5.6 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain Nuc_deoxyri_tr2 PF15891.5 AIM23187.1 - 0.046 14.0 0.5 2.8 8.3 0.0 2.7 3 0 0 3 3 2 0 Nucleoside 2-deoxyribosyltransferase like MobB PF03205.14 AIM23187.1 - 0.075 12.9 0.0 34 4.3 0.0 3.3 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Septin PF00735.18 AIM23187.1 - 0.11 11.7 0.0 16 4.7 0.0 2.4 2 0 0 2 2 2 0 Septin AAA_28 PF13521.6 AIM23187.1 - 0.12 12.6 0.0 26 5.0 0.0 3.0 2 1 1 3 3 3 0 AAA domain Ploopntkinase3 PF18751.1 AIM23187.1 - 0.13 12.2 0.0 2.4 8.0 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 PQQ_2 PF13360.6 AIM23188.1 - 8.4e-59 199.0 8.8 7.5e-54 182.8 6.6 2.2 1 1 1 2 2 2 2 PQQ-like domain PQQ_3 PF13570.6 AIM23188.1 - 2e-35 120.4 17.3 9.7e-07 29.1 0.1 8.5 8 0 0 8 8 8 8 PQQ-like domain PQQ PF01011.21 AIM23188.1 - 1.1e-32 110.3 8.8 7e-07 28.9 0.1 7.3 7 1 0 7 7 7 5 PQQ enzyme repeat RAMA PF18755.1 AIM23188.1 - 0.0073 16.7 0.1 0.32 11.4 0.0 2.6 2 0 0 2 2 2 1 Restriction Enzyme Adenine Methylase Associated LPAM_1 PF08139.12 AIM23188.1 - 0.12 12.9 1.6 0.33 11.5 1.6 1.8 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site ESX-1_EspG PF14011.6 AIM23188.1 - 0.24 11.0 1.8 13 5.4 0.0 2.7 2 1 1 3 3 3 0 EspG family TPR_21 PF09976.9 AIM23189.1 - 8.3e-58 195.3 12.9 9.3e-58 195.1 12.9 1.0 1 0 0 1 1 1 1 Tetratricopeptide repeat-like domain TPR_19 PF14559.6 AIM23189.1 - 6.5e-05 23.4 17.5 0.046 14.2 0.4 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 AIM23189.1 - 6.8e-05 23.4 10.1 0.0012 19.4 1.0 3.2 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 AIM23189.1 - 0.00075 20.1 11.1 0.91 10.5 0.1 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 AIM23189.1 - 0.011 15.8 6.8 0.84 9.9 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF3911 PF13050.6 AIM23189.1 - 0.03 14.4 0.2 0.055 13.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3911) ANAPC3 PF12895.7 AIM23189.1 - 0.032 14.5 1.3 0.055 13.7 0.5 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 AIM23189.1 - 0.046 14.0 5.7 0.76 10.1 0.3 3.2 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 AIM23189.1 - 0.056 13.3 3.3 15 5.6 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 AIM23189.1 - 0.064 12.9 3.5 0.31 10.8 0.2 3.3 4 0 0 4 4 4 0 TPR repeat TPR_8 PF13181.6 AIM23189.1 - 0.087 13.1 4.0 2.1 8.8 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat YfdX PF10938.8 AIM23189.1 - 0.11 12.4 10.1 0.33 10.9 0.1 3.4 2 2 1 3 3 3 0 YfdX protein ZapA PF05164.13 AIM23189.1 - 2.6 8.6 6.6 87 3.6 6.0 2.5 1 1 0 1 1 1 0 Cell division protein ZapA TPR_4 PF07721.14 AIM23189.1 - 2.6 8.9 7.6 27 5.8 0.0 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat tRNA-synt_His PF13393.6 AIM23190.1 - 5.9e-47 160.5 0.0 7.5e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.25 AIM23190.1 - 1.4e-38 132.7 0.0 2e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 AIM23190.1 - 1e-10 41.6 0.0 2.2e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.20 AIM23190.1 - 0.0033 16.5 0.1 0.43 9.6 0.1 2.5 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) GcpE PF04551.14 AIM23191.1 - 5e-131 436.9 0.2 5.9e-131 436.7 0.2 1.0 1 0 0 1 1 1 1 GcpE protein Radical_SAM PF04055.21 AIM23191.1 - 0.12 12.8 0.0 0.36 11.2 0.0 1.8 1 1 0 1 1 1 0 Radical SAM superfamily DUF4115 PF13464.6 AIM23192.1 - 2.4e-25 88.5 0.0 5.9e-25 87.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4115) HTH_25 PF13413.6 AIM23192.1 - 2.9e-16 59.1 0.3 4.3e-16 58.5 0.3 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 AIM23192.1 - 3.6e-09 36.8 0.4 1e-08 35.4 0.4 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 AIM23192.1 - 2.7e-08 33.7 0.1 1e-07 31.9 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 AIM23192.1 - 4.2e-07 29.9 2.3 4.6e-07 29.8 0.1 2.0 2 0 0 2 2 2 1 Helix-turn-helix TPR_21 PF09976.9 AIM23192.1 - 0.018 14.8 1.0 0.03 14.0 1.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain HTH_37 PF13744.6 AIM23192.1 - 0.037 14.0 0.2 0.037 14.0 0.2 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.6 AIM23192.1 - 0.094 12.5 0.1 0.21 11.4 0.1 1.6 1 0 0 1 1 1 0 Homeodomain-like domain DivIC PF04977.15 AIM23192.1 - 0.39 10.5 1.3 4.5 7.1 0.2 2.2 2 0 0 2 2 2 0 Septum formation initiator TPR_12 PF13424.6 AIM23193.1 - 7.7e-14 51.7 12.6 8.3e-07 29.2 0.0 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 AIM23193.1 - 8.4e-14 50.5 10.8 0.00021 21.2 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 AIM23193.1 - 2.3e-13 49.2 2.5 1.8e-05 24.6 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 AIM23193.1 - 2.6e-12 47.1 19.4 0.00079 19.9 0.4 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 AIM23193.1 - 3.8e-11 42.3 10.3 0.00019 21.1 0.2 4.1 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 AIM23193.1 - 1.3e-09 38.1 18.6 0.001 19.7 1.9 5.3 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 AIM23193.1 - 1.8e-09 38.1 22.4 0.0027 18.3 4.4 4.4 1 1 4 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 AIM23193.1 - 2.1e-09 36.9 9.1 0.0084 15.8 0.0 3.6 2 1 1 3 3 3 3 TPR repeat TPR_6 PF13174.6 AIM23193.1 - 8.1e-08 32.4 10.1 0.021 15.5 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 AIM23193.1 - 4.5e-06 26.7 14.1 0.00026 21.1 0.1 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat HemY_N PF07219.13 AIM23193.1 - 0.00028 21.0 8.0 0.0012 19.0 1.0 3.1 2 2 1 3 3 3 1 HemY protein N-terminus TPR_15 PF13429.6 AIM23193.1 - 0.0005 19.4 9.2 0.0091 15.2 2.5 3.5 1 1 2 3 3 3 2 Tetratricopeptide repeat Coatomer_E PF04733.14 AIM23193.1 - 0.00088 18.8 0.3 0.096 12.1 0.0 2.4 3 0 0 3 3 3 1 Coatomer epsilon subunit TPR_7 PF13176.6 AIM23193.1 - 0.00099 19.0 9.1 3 8.1 0.4 4.3 5 0 0 5 5 4 2 Tetratricopeptide repeat YfdX PF10938.8 AIM23193.1 - 0.0076 16.2 0.2 0.08 12.9 0.0 2.6 1 1 1 2 2 2 1 YfdX protein TPR_9 PF13371.6 AIM23193.1 - 0.011 15.9 1.6 0.011 15.9 1.6 3.3 1 1 2 3 3 3 0 Tetratricopeptide repeat FliG_N PF14842.6 AIM23193.1 - 0.045 14.3 0.2 3.9 8.1 0.0 2.4 2 0 0 2 2 2 0 FliG N-terminal domain PTS_IIA PF02255.16 AIM23193.1 - 0.055 13.5 1.3 7.1 6.8 0.0 2.6 2 1 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit TPR_10 PF13374.6 AIM23193.1 - 0.1 12.5 18.8 0.31 11.0 1.1 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat CysG_dimeriser PF10414.9 AIM23193.1 - 0.26 11.0 9.2 3.8 7.3 0.3 4.0 4 0 0 4 4 4 0 Sirohaem synthase dimerisation region DUF4810 PF16068.5 AIM23193.1 - 0.32 11.6 4.2 72 4.0 0.1 4.0 3 1 0 4 4 4 0 Domain of unknown function (DUF4810) TPR_21 PF09976.9 AIM23193.1 - 0.56 9.9 15.3 16 5.1 10.8 3.6 1 1 0 2 2 2 0 Tetratricopeptide repeat-like domain Vta1_C PF18097.1 AIM23193.1 - 0.92 9.3 4.2 0.9 9.3 0.3 2.8 3 0 0 3 3 2 0 Vta1 C-terminal domain TPR_20 PF14561.6 AIM23193.1 - 3.1 8.2 10.2 7.5 7.0 2.5 3.5 2 2 0 2 2 2 0 Tetratricopeptide repeat Radical_SAM PF04055.21 AIM23194.1 - 4.8e-18 66.1 0.1 1.6e-17 64.4 0.1 1.8 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 AIM23194.1 - 0.00072 19.7 0.0 0.0019 18.4 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain NDK PF00334.19 AIM23195.1 - 3.4e-56 189.0 0.0 3.7e-56 188.9 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase SseB_C PF14581.6 AIM23196.1 - 3.7e-35 120.2 0.1 8.8e-35 119.0 0.0 1.7 2 0 0 2 2 2 1 SseB protein C-terminal domain SseB PF07179.12 AIM23196.1 - 4.5e-24 85.1 0.2 7.3e-24 84.4 0.2 1.3 1 0 0 1 1 1 1 SseB protein N-terminal domain Peptidase_M17 PF00883.21 AIM23197.1 - 9.2e-106 353.6 0.0 1.1e-105 353.4 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain DUF3663 PF12404.8 AIM23197.1 - 7e-37 125.3 0.3 1.4e-36 124.4 0.3 1.5 1 0 0 1 1 1 1 Peptidase Fe-S_assembly PF04384.13 AIM23198.1 - 1.3e-32 112.2 2.3 1.4e-32 112.1 2.3 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster assembly Fer2 PF00111.27 AIM23199.1 - 8.9e-15 54.4 4.0 1.1e-14 54.2 4.0 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 AIM23199.1 - 0.037 14.1 0.2 0.074 13.1 0.1 1.6 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain HSP70 PF00012.20 AIM23200.1 - 2.2e-197 656.9 0.1 2.6e-197 656.7 0.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 AIM23200.1 - 7.2e-13 48.0 0.1 4.9e-11 42.0 0.1 2.5 2 1 0 2 2 2 2 MreB/Mbl protein HSCB_C PF07743.13 AIM23201.1 - 4.9e-15 55.8 6.9 4.9e-15 55.8 6.9 2.2 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 AIM23201.1 - 3.6e-06 27.0 0.1 6.3e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain YfbU PF03887.14 AIM23201.1 - 0.0026 17.8 0.1 0.0041 17.2 0.1 1.4 1 1 0 1 1 1 1 YfbU domain SRA1 PF07304.11 AIM23201.1 - 0.0053 16.6 0.1 0.0092 15.8 0.1 1.3 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) BDV_P24 PF06595.11 AIM23201.1 - 0.029 14.3 0.1 0.033 14.1 0.1 1.1 1 0 0 1 1 1 0 Borna disease virus P24 protein CREPT PF16566.5 AIM23201.1 - 0.34 11.1 6.1 0.1 12.8 3.0 1.6 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF1525 PF07511.11 AIM23201.1 - 2.2 8.4 5.4 1.8 8.7 0.4 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1525) Fe-S_biosyn PF01521.20 AIM23202.1 - 5.3e-27 94.2 0.0 5.9e-27 94.1 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis NifU_N PF01592.16 AIM23203.1 - 1.3e-56 190.3 0.2 1.4e-56 190.1 0.2 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain CO_deh_flav_C PF03450.17 AIM23203.1 - 0.13 12.4 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase flavoprotein C-terminal domain Aminotran_5 PF00266.19 AIM23204.1 - 6.7e-88 295.1 0.0 8e-88 294.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 AIM23204.1 - 2.7e-06 26.2 0.0 1.1e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 AIM23204.1 - 0.00011 21.7 0.1 0.00013 21.3 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 AIM23204.1 - 0.055 12.8 0.1 0.1 11.9 0.1 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Rrf2 PF02082.20 AIM23205.1 - 8.1e-28 96.6 0.1 1.4e-27 95.8 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulator MarR_2 PF12802.7 AIM23205.1 - 0.0023 17.8 0.0 0.0046 16.8 0.0 1.5 1 0 0 1 1 1 1 MarR family HrcA_DNA-bdg PF03444.15 AIM23205.1 - 0.008 15.8 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix transcription repressor, HrcA DNA-binding HTH_24 PF13412.6 AIM23205.1 - 0.012 15.1 0.0 0.033 13.7 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_47 PF16221.5 AIM23205.1 - 0.11 12.0 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 winged helix-turn-helix SpoU_methylase PF00588.19 AIM23206.1 - 5e-34 117.5 0.0 1.4e-33 116.0 0.0 1.6 2 0 0 2 2 2 1 SpoU rRNA Methylase family Methyltrn_RNA_4 PF09936.9 AIM23206.1 - 0.0019 18.1 0.0 0.095 12.6 0.0 2.2 1 1 1 2 2 2 2 SAM-dependent RNA methyltransferase Inositol_P PF00459.25 AIM23207.1 - 2.4e-71 240.4 0.0 2.7e-71 240.3 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.20 AIM23207.1 - 0.0037 16.8 0.0 0.0061 16.0 0.0 1.4 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain NicO PF03824.16 AIM23208.1 - 2.5e-41 141.9 19.0 1.5e-39 136.0 19.0 2.2 1 1 0 1 1 1 1 High-affinity nickel-transport protein DsbD PF02683.15 AIM23208.1 - 5 7.0 20.8 2.4 8.0 7.2 2.6 2 1 0 2 2 2 0 Cytochrome C biogenesis protein transmembrane region DUF1007 PF06226.13 AIM23209.1 - 4.6e-63 213.0 0.2 5.2e-63 212.8 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1007) ORF_12_N PF18042.1 AIM23209.1 - 0.063 13.7 0.4 0.2 12.1 0.0 1.9 2 0 0 2 2 2 0 ORF 12 gene product N-terminal PRD PF00874.20 AIM23211.1 - 4.2e-18 65.4 0.0 7.2e-17 61.5 0.0 2.5 2 1 0 2 2 2 1 PRD domain MFS_1_like PF12832.7 AIM23212.1 - 1.7e-43 148.9 23.5 5.7e-43 147.2 23.5 1.7 1 1 0 1 1 1 1 MFS_1 like family LacY_symp PF01306.19 AIM23212.1 - 2.3e-13 49.7 10.8 3.4e-13 49.1 10.8 1.2 1 0 0 1 1 1 1 LacY proton/sugar symporter Nuc_H_symport PF03825.16 AIM23212.1 - 6.5e-13 48.4 13.4 7.9e-13 48.2 13.4 1.1 1 0 0 1 1 1 1 Nucleoside H+ symporter MFS_1 PF07690.16 AIM23212.1 - 2.8e-07 29.8 50.1 3.2e-07 29.6 34.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SHMT PF00464.19 AIM23213.1 - 3.5e-189 628.5 0.2 4.1e-189 628.3 0.2 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 AIM23213.1 - 4.9e-09 35.8 0.0 6.8e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 AIM23213.1 - 5.4e-06 25.6 0.0 7.8e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 AIM23213.1 - 2.8e-05 23.6 0.0 6.2e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.20 AIM23213.1 - 0.0022 16.8 0.0 0.0039 16.0 0.0 1.4 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain DegT_DnrJ_EryC1 PF01041.17 AIM23213.1 - 0.028 13.7 0.2 0.037 13.3 0.2 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family NAD_binding_1 PF00175.21 AIM23214.1 - 7.8e-17 61.9 0.0 1.9e-16 60.6 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.22 AIM23214.1 - 5e-14 52.8 0.0 1.1e-13 51.7 0.0 1.6 1 0 0 1 1 1 1 Globin FAD_binding_6 PF00970.24 AIM23214.1 - 4.5e-10 39.8 0.0 8.8e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Protoglobin PF11563.8 AIM23214.1 - 3.8e-05 23.6 0.0 6.9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Protoglobin DUF1987 PF09345.10 AIM23214.1 - 0.0063 16.2 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1987) BshC PF10079.9 AIM23214.1 - 0.009 14.8 0.0 0.013 14.3 0.0 1.1 1 0 0 1 1 1 1 Bacillithiol biosynthesis BshC Cytochrom_C PF00034.21 AIM23215.1 - 7.6e-22 78.3 0.6 5.3e-08 33.9 0.0 3.4 3 0 0 3 3 3 3 Cytochrome c Cytochrome_CBB3 PF13442.6 AIM23215.1 - 6.3e-21 74.5 4.4 9.7e-10 38.6 0.1 3.6 3 0 0 3 3 3 3 Cytochrome C oxidase, cbb3-type, subunit III Paired_CXXCH_1 PF09699.10 AIM23215.1 - 1.6e-05 24.5 4.8 0.35 10.6 0.1 3.4 3 0 0 3 3 3 3 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrome_C7 PF14522.6 AIM23215.1 - 0.00015 21.7 0.4 6.9 6.8 0.0 3.3 3 0 0 3 3 3 3 Cytochrome c7 and related cytochrome c CCP_MauG PF03150.14 AIM23215.1 - 0.22 12.2 5.4 4 8.1 0.0 3.2 2 1 1 3 3 3 0 Di-haem cytochrome c peroxidase DUF1924 PF09086.11 AIM23215.1 - 0.26 11.7 3.0 20 5.6 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1924) GSu_C4xC__C2xCH PF09698.10 AIM23215.1 - 0.68 10.8 14.4 0.31 11.9 1.0 3.8 4 0 0 4 4 4 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) NAD_binding_8 PF13450.6 AIM23216.1 - 2.4e-11 43.7 0.0 6.7e-11 42.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AIM23216.1 - 2.4e-05 24.1 0.0 5.7e-05 22.9 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AIM23216.1 - 0.00052 19.2 0.0 0.0047 16.1 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 AIM23216.1 - 0.022 14.0 0.0 0.048 12.9 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 AIM23216.1 - 0.041 14.4 0.0 0.13 12.9 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 AIM23216.1 - 0.042 13.1 0.0 0.077 12.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 AIM23216.1 - 0.051 12.8 0.0 0.12 11.6 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 AIM23216.1 - 0.064 13.2 0.1 0.18 11.8 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 AIM23216.1 - 0.065 12.6 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase K_oxygenase PF13434.6 AIM23216.1 - 0.15 11.1 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 AIM23216.1 - 0.19 10.4 0.0 0.31 9.7 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Aldedh PF00171.22 AIM23217.1 - 1.3e-163 544.8 0.0 1.5e-163 544.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 AIM23217.1 - 0.26 10.3 0.0 0.44 9.5 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) BPD_transp_1 PF00528.22 AIM23218.1 - 4.1e-14 52.7 11.9 4.1e-14 52.7 11.9 1.5 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component HupE_UreJ_2 PF13795.6 AIM23218.1 - 0.036 13.7 2.8 0.058 13.0 0.0 2.3 2 1 0 2 2 2 0 HupE / UreJ protein DUF1748 PF08520.10 AIM23218.1 - 0.063 13.2 0.3 2.4 8.1 0.0 2.4 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1748) BPD_transp_1 PF00528.22 AIM23219.1 - 1.8e-16 60.4 17.9 1.8e-16 60.4 17.9 2.2 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 AIM23220.1 - 4.5e-33 114.7 0.0 9.4e-33 113.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter TOBE_2 PF08402.10 AIM23220.1 - 6.2e-15 55.1 0.1 1.8e-14 53.7 0.1 1.8 1 0 0 1 1 1 1 TOBE domain AAA_21 PF13304.6 AIM23220.1 - 1.5e-07 31.6 0.1 0.00026 20.9 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIM23220.1 - 0.0013 18.2 0.1 0.065 12.7 0.1 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AIM23220.1 - 0.0067 16.7 0.2 0.032 14.5 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AIM23220.1 - 0.01 16.2 0.3 0.03 14.7 0.3 1.9 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 AIM23220.1 - 0.017 15.0 0.0 0.17 11.8 0.0 2.4 3 0 0 3 3 3 0 RsgA GTPase PhoH PF02562.16 AIM23220.1 - 0.026 14.0 0.0 4.2 6.8 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_29 PF13555.6 AIM23220.1 - 0.041 13.6 0.0 0.087 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 AIM23220.1 - 0.078 13.4 0.0 0.42 11.0 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 AIM23220.1 - 0.11 12.6 0.3 0.55 10.4 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 AIM23220.1 - 0.13 12.5 0.7 7 6.9 0.0 3.0 3 1 0 3 3 3 0 AAA domain AAA_23 PF13476.6 AIM23220.1 - 0.18 12.3 0.2 0.47 10.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain SBP_bac_8 PF13416.6 AIM23221.1 - 1.2e-27 97.4 6.2 1.6e-27 97.0 6.2 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AIM23221.1 - 5.2e-17 62.1 3.7 6.3e-16 58.5 3.7 2.0 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AIM23221.1 - 1.1e-16 61.6 5.5 1.6e-16 61.2 5.5 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein Glyco_hydro_62 PF03664.13 AIM23221.1 - 0.023 14.0 0.2 0.051 12.9 0.2 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 62 Ral PF11058.8 AIM23221.1 - 0.09 12.4 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Antirestriction protein Ral DUF3303 PF11746.8 AIM23221.1 - 0.11 12.8 0.0 4.1 7.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3303) Phosphonate-bd PF12974.7 AIM23221.1 - 0.14 11.7 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein Aldedh PF00171.22 AIM23222.1 - 2.6e-156 520.8 0.0 3.2e-156 520.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LysR_substrate PF03466.20 AIM23223.1 - 6.1e-44 149.9 1.0 7.6e-44 149.6 1.0 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM23223.1 - 4.2e-20 71.4 2.3 6.6e-20 70.8 1.3 1.8 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family DUF2062 PF09835.9 AIM23223.1 - 0.0013 18.6 0.1 0.0024 17.8 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2062) P-II PF00543.22 AIM23224.1 - 2.2e-44 150.2 3.7 2.5e-44 150.1 3.7 1.0 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II Nit_Regul_Hom PF10126.9 AIM23224.1 - 0.061 13.3 0.1 0.079 13.0 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein, homolog of nitrogen regulatory protein PII DUF3240 PF11582.8 AIM23224.1 - 0.075 13.2 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3240) NAD_synthase PF02540.17 AIM23225.1 - 2.7e-71 239.5 0.0 3.5e-71 239.1 0.0 1.1 1 0 0 1 1 1 1 NAD synthase CN_hydrolase PF00795.22 AIM23225.1 - 1.5e-25 90.1 0.0 2.1e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase QueC PF06508.13 AIM23225.1 - 0.0019 17.7 0.0 0.0034 16.9 0.0 1.4 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC DUF2312 PF10073.9 AIM23225.1 - 0.18 11.5 0.2 0.43 10.2 0.2 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) Sigma54_activat PF00158.26 AIM23226.1 - 2.8e-72 241.9 0.1 7.5e-72 240.5 0.1 1.7 2 0 0 2 2 2 1 Sigma-54 interaction domain Response_reg PF00072.24 AIM23226.1 - 9.9e-32 109.4 0.1 2.2e-31 108.3 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Sigma54_activ_2 PF14532.6 AIM23226.1 - 1e-21 77.5 0.1 6.4e-21 74.9 0.1 2.3 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_5 PF07728.14 AIM23226.1 - 2.6e-06 27.5 0.0 4.7e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 AIM23226.1 - 0.00077 19.9 0.0 0.0023 18.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AIM23226.1 - 0.0013 19.1 0.9 0.0044 17.4 0.5 2.3 1 1 0 1 1 1 1 AAA ATPase domain HTH_8 PF02954.19 AIM23226.1 - 0.0024 17.6 0.2 0.011 15.5 0.2 2.3 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family Mg_chelatase PF01078.21 AIM23226.1 - 0.0097 15.3 0.1 2.1 7.7 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI UPF0175 PF03683.13 AIM23226.1 - 0.011 15.4 0.1 0.059 13.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0175) IstB_IS21 PF01695.17 AIM23226.1 - 0.011 15.4 0.1 0.029 14.1 0.1 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 AIM23226.1 - 0.029 14.1 0.0 0.065 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 AIM23226.1 - 0.03 14.2 0.0 0.084 12.7 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 AIM23226.1 - 0.041 14.0 0.0 0.094 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) OKR_DC_1_N PF03709.15 AIM23226.1 - 0.07 13.4 0.0 0.5 10.7 0.0 2.3 3 0 0 3 3 3 0 Orn/Lys/Arg decarboxylase, N-terminal domain AAA_7 PF12775.7 AIM23226.1 - 0.094 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region MCM PF00493.23 AIM23226.1 - 0.13 11.4 0.0 0.32 10.1 0.0 1.6 1 1 0 1 1 1 0 MCM P-loop domain Lipoprotein_20 PF13942.6 AIM23227.1 - 1.1e-76 256.6 6.1 1.4e-76 256.3 6.1 1.1 1 0 0 1 1 1 1 YfhG lipoprotein THOC7 PF05615.13 AIM23227.1 - 0.00025 21.3 0.6 0.00037 20.8 0.6 1.3 1 0 0 1 1 1 1 Tho complex subunit 7 DUF4349 PF14257.6 AIM23227.1 - 0.046 13.2 2.2 0.074 12.5 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Striatin PF08232.12 AIM23227.1 - 0.28 11.8 6.7 0.57 10.8 6.7 1.5 1 1 0 1 1 1 0 Striatin family Snapin_Pallidin PF14712.6 AIM23227.1 - 0.52 10.8 12.8 0.13 12.7 5.4 2.3 1 1 1 2 2 2 0 Snapin/Pallidin FlxA PF14282.6 AIM23227.1 - 1.1 9.3 15.4 0.024 14.6 8.7 1.8 2 0 0 2 2 2 0 FlxA-like protein CorA PF01544.18 AIM23227.1 - 1.4 8.2 4.5 2.3 7.4 4.5 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein HATPase_c PF02518.26 AIM23228.1 - 4.7e-18 65.7 0.0 2.4e-17 63.4 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AIM23228.1 - 4.2e-14 52.3 1.0 2.3e-13 50.0 1.0 2.3 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AIM23228.1 - 0.00064 20.0 0.2 0.0031 17.9 0.1 2.4 2 0 0 2 2 2 1 HAMP domain 4HB_MCP_1 PF12729.7 AIM23228.1 - 0.0017 18.0 1.0 0.51 9.9 0.1 3.0 3 0 0 3 3 3 2 Four helix bundle sensory module for signal transduction MitMem_reg PF13012.6 AIM23228.1 - 0.059 13.8 1.2 0.11 13.0 0.1 2.0 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function HATPase_c_5 PF14501.6 AIM23228.1 - 0.14 12.0 0.0 0.4 10.6 0.0 1.8 1 0 0 1 1 1 0 GHKL domain FlgN PF05130.12 AIM23228.1 - 1.1 9.8 5.8 0.2 12.2 0.4 2.3 2 1 0 2 2 2 0 FlgN protein GATase_5 PF13507.6 AIM23229.1 - 1.1e-105 352.4 0.1 1.8e-105 351.7 0.1 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain FGAR-AT_N PF18076.1 AIM23229.1 - 1.8e-45 153.6 0.0 4.1e-45 152.5 0.0 1.7 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal AIRS_C PF02769.22 AIM23229.1 - 2.2e-44 151.3 4.1 1.7e-27 96.5 0.0 2.9 3 0 0 3 3 3 2 AIR synthase related protein, C-terminal domain FGAR-AT_linker PF18072.1 AIM23229.1 - 1.3e-23 83.2 0.0 4.9e-23 81.4 0.0 2.1 2 0 0 2 2 2 1 Formylglycinamide ribonucleotide amidotransferase linker domain AIRS PF00586.24 AIM23229.1 - 0.0031 18.1 0.2 0.24 12.1 0.0 3.3 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain SBP_bac_3 PF00497.20 AIM23230.1 - 4.8e-32 111.2 0.0 6.6e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 SLT PF01464.20 AIM23230.1 - 4.4e-25 87.6 0.0 7.4e-25 86.9 0.0 1.3 1 0 0 1 1 1 1 Transglycosylase SLT domain Lysozyme_like PF13702.6 AIM23230.1 - 0.034 13.8 0.0 0.081 12.6 0.0 1.8 1 1 0 1 1 1 0 Lysozyme-like MafB19-deam PF14437.6 AIM23231.1 - 1.2e-31 109.3 0.0 1.4e-31 109.1 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 AIM23231.1 - 3.1e-26 91.2 0.0 5.2e-26 90.5 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region SNAD4 PF18750.1 AIM23231.1 - 0.00011 22.2 0.0 0.00034 20.7 0.0 1.7 2 0 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 Bd3614-deam PF14439.6 AIM23231.1 - 0.00038 20.6 0.0 0.00053 20.1 0.0 1.4 1 0 0 1 1 1 1 Bd3614-like deaminase APOBEC3 PF18771.1 AIM23231.1 - 0.0013 18.8 0.0 0.035 14.2 0.0 2.1 2 0 0 2 2 2 1 APOBEC3 APOBEC2 PF18772.1 AIM23231.1 - 0.0021 18.2 0.0 0.0043 17.1 0.0 1.5 2 0 0 2 2 2 1 APOBEC2 APOBEC_N PF08210.11 AIM23231.1 - 0.0033 17.3 0.0 0.0061 16.5 0.0 1.4 2 0 0 2 2 2 1 APOBEC-like N-terminal domain NAD2 PF18782.1 AIM23231.1 - 0.0054 16.9 0.0 0.011 15.9 0.0 1.5 2 0 0 2 2 2 1 Novel AID APOBEC clade 2 NAD1 PF18778.1 AIM23231.1 - 0.006 16.7 0.0 0.014 15.5 0.0 1.6 2 0 0 2 2 2 1 Novel AID APOBEC clade 1 DUF2157 PF09925.9 AIM23232.1 - 7.5e-08 32.3 11.3 7.5e-08 32.3 11.3 3.6 2 1 1 3 3 3 2 Predicted membrane protein (DUF2157) DUF2339 PF10101.9 AIM23232.1 - 1.4 7.4 45.9 3.7 6.0 45.8 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2339) HAD PF12710.7 AIM23233.1 - 5.5e-14 53.0 0.0 6.8e-14 52.7 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PTS_EIIC PF02378.18 AIM23234.1 - 6.3e-33 114.2 26.3 6.3e-33 114.2 26.3 2.2 2 0 0 2 2 2 1 Phosphotransferase system, EIIC PTS_EIIB PF00367.20 AIM23234.1 - 4.2e-11 42.1 0.1 8.3e-11 41.2 0.1 1.5 1 0 0 1 1 1 1 phosphotransferase system, EIIB FeoB_C PF07664.12 AIM23234.1 - 1.8 8.3 6.1 0.45 10.2 0.2 3.2 3 0 0 3 3 3 0 Ferrous iron transport protein B C terminus SIS_2 PF13580.6 AIM23235.1 - 3.3e-09 36.9 0.9 1.2e-08 35.1 0.1 2.3 2 1 0 2 2 2 1 SIS domain SIS PF01380.22 AIM23235.1 - 1.3e-08 34.7 0.3 1.1e-07 31.8 0.0 2.1 2 0 0 2 2 2 1 SIS domain UBA_4 PF14555.6 AIM23235.1 - 0.0015 18.3 0.2 0.43 10.4 0.0 2.5 1 1 1 2 2 2 2 UBA-like domain ANTAR PF03861.14 AIM23235.1 - 0.024 14.5 3.6 2.6 7.9 0.2 2.6 2 0 0 2 2 2 0 ANTAR domain SIS PF01380.22 AIM23236.1 - 1.8e-27 95.7 0.5 2.9e-27 95.1 0.5 1.3 1 0 0 1 1 1 1 SIS domain HTH_6 PF01418.17 AIM23236.1 - 6.7e-27 93.3 0.1 1.4e-26 92.2 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain, rpiR family SIS_2 PF13580.6 AIM23236.1 - 2e-07 31.1 0.3 1.5e-05 25.0 0.1 2.5 1 1 1 2 2 2 1 SIS domain HTH_Crp_2 PF13545.6 AIM23236.1 - 0.014 15.4 0.0 0.039 13.9 0.0 1.8 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_37 PF13744.6 AIM23236.1 - 0.014 15.3 0.1 0.05 13.6 0.1 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain UPF0175 PF03683.13 AIM23236.1 - 0.021 14.6 0.1 0.057 13.1 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) IF2_N PF04760.15 AIM23236.1 - 0.029 14.2 0.2 4 7.3 0.0 2.8 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region Rrf2 PF02082.20 AIM23236.1 - 0.084 13.2 1.3 1.2 9.6 0.0 3.0 3 1 1 4 4 4 0 Transcriptional regulator MarR PF01047.22 AIM23236.1 - 0.095 12.6 0.0 0.62 10.0 0.0 2.2 2 0 0 2 2 2 0 MarR family Fer4 PF00037.27 AIM23237.1 - 1.1e-07 31.3 14.3 6.7e-06 25.7 2.0 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_7 PF12838.7 AIM23237.1 - 3e-07 30.9 11.9 5.3e-07 30.1 11.9 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 AIM23237.1 - 7.8e-07 28.8 12.8 0.00017 21.5 2.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 AIM23237.1 - 2e-05 24.6 13.8 3.2e-05 24.0 13.8 1.4 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 AIM23237.1 - 2.6e-05 24.3 12.8 6.7e-05 23.0 13.0 1.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 AIM23237.1 - 9.1e-05 22.5 25.2 0.0018 18.3 14.9 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain GF_recep_IV PF14843.6 AIM23237.1 - 0.00071 19.4 7.9 0.00084 19.1 7.9 1.1 1 0 0 1 1 1 1 Growth factor receptor domain IV Fer4_16 PF13484.6 AIM23237.1 - 0.0046 17.9 14.3 0.007 17.3 6.3 2.3 1 1 2 3 3 2 1 4Fe-4S double cluster binding domain Fer4_6 PF12837.7 AIM23237.1 - 0.0066 16.5 16.2 0.0093 16.0 4.4 2.5 2 1 0 2 2 2 1 4Fe-4S binding domain Fer4_4 PF12800.7 AIM23237.1 - 0.039 14.4 2.2 0.039 14.4 2.2 2.7 2 1 0 2 2 2 0 4Fe-4S binding domain Fer4_20 PF14691.6 AIM23237.1 - 0.044 13.5 1.6 0.044 13.5 1.6 2.1 1 1 1 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_8 PF13183.6 AIM23237.1 - 0.19 12.2 15.5 12 6.4 3.2 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 AIM23237.1 - 0.26 12.3 16.1 0.69 11.0 3.4 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_17 PF13534.6 AIM23237.1 - 0.36 11.4 15.1 1.1e+02 3.4 15.2 2.5 1 1 0 1 1 1 0 4Fe-4S dicluster domain ACPS PF01648.20 AIM23238.1 - 2.9e-23 82.2 0.0 3.2e-23 82.0 0.0 1.0 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Tecti-min-caps PF09300.10 AIM23238.1 - 0.0074 16.3 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Tectiviridae, minor capsid Cytidylate_kin2 PF13189.6 AIM23238.1 - 0.11 12.6 0.1 0.12 12.4 0.1 1.1 1 0 0 1 1 1 0 Cytidylate kinase-like family PdxJ PF03740.13 AIM23239.1 - 1.1e-104 348.7 3.4 1.2e-104 348.5 3.4 1.0 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthesis protein PdxJ AP_endonuc_2 PF01261.24 AIM23239.1 - 0.00032 20.2 2.3 0.0043 16.5 2.3 2.2 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel RecO_C PF02565.15 AIM23240.1 - 6.9e-24 84.4 2.0 1.1e-23 83.8 2.0 1.2 1 0 0 1 1 1 1 Recombination protein O C terminal RecO_N PF11967.8 AIM23240.1 - 2.9e-23 81.6 0.0 5.1e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 Recombination protein O N terminal MMR_HSR1 PF01926.23 AIM23241.1 - 1.1e-22 80.3 0.0 2.5e-22 79.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase KH_2 PF07650.17 AIM23241.1 - 9.2e-20 70.3 0.8 3.8e-19 68.3 0.5 2.1 2 0 0 2 2 2 1 KH domain FeoB_N PF02421.18 AIM23241.1 - 8.8e-15 54.6 0.2 1.4e-14 53.9 0.2 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 AIM23241.1 - 1.5e-08 34.4 0.4 2.8e-06 27.0 0.4 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 AIM23241.1 - 2.4e-07 30.8 0.6 0.00041 20.3 0.1 2.3 1 1 1 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 AIM23241.1 - 6e-07 29.7 0.2 1.7e-05 24.9 0.1 2.2 1 1 1 2 2 2 1 Dynamin family AIG1 PF04548.16 AIM23241.1 - 9e-07 28.4 0.0 1.7e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 AIG1 family PduV-EutP PF10662.9 AIM23241.1 - 7.7e-06 25.7 0.2 0.0017 18.1 0.2 2.4 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 AIM23241.1 - 0.00015 22.0 0.0 0.00034 20.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 AIM23241.1 - 0.0048 16.5 0.7 0.38 10.3 0.1 2.3 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Ras PF00071.22 AIM23241.1 - 0.012 15.3 0.1 0.4 10.3 0.0 2.7 2 1 0 2 2 2 0 Ras family SRPRB PF09439.10 AIM23241.1 - 0.014 14.8 0.1 0.034 13.6 0.1 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Roc PF08477.13 AIM23241.1 - 0.014 15.6 0.7 0.056 13.7 0.1 2.4 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1_Xtn PF16897.5 AIM23241.1 - 0.015 15.3 0.0 0.034 14.2 0.0 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain DUF521 PF04412.13 AIM23241.1 - 0.026 13.2 0.0 0.042 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) AAA_24 PF13479.6 AIM23241.1 - 0.081 12.6 0.0 0.2 11.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 AIM23241.1 - 0.11 13.0 0.0 0.23 12.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Ribonucleas_3_3 PF14622.6 AIM23242.1 - 9.7e-34 116.3 0.0 1.4e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 AIM23242.1 - 3.9e-20 72.4 0.0 7.4e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.26 AIM23242.1 - 1.8e-14 54.1 0.0 3e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 AIM23242.1 - 1.8e-05 24.9 0.0 3.4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 Peptidase_S24 PF00717.23 AIM23243.1 - 1.5e-20 72.9 0.1 2.5e-20 72.2 0.1 1.4 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 AIM23243.1 - 1.6e-10 40.9 0.0 1.1e-07 31.7 0.0 2.3 2 0 0 2 2 2 2 Signal peptidase, peptidase S26 GTP_EFTU PF00009.27 AIM23244.1 - 1.6e-51 174.6 0.6 2.5e-51 174.0 0.1 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 AIM23244.1 - 5.4e-49 164.8 2.7 8.9e-49 164.1 2.7 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 AIM23244.1 - 3.9e-20 71.7 0.0 8.5e-20 70.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 AIM23244.1 - 5.7e-12 45.8 0.3 1.4e-11 44.6 0.3 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 AIM23244.1 - 2.9e-05 24.1 0.0 0.00021 21.3 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 AIM23244.1 - 0.00021 21.0 0.0 0.00035 20.2 0.0 1.3 1 0 0 1 1 1 1 Ras family EFG_II PF14492.6 AIM23244.1 - 0.00035 20.6 0.0 0.0012 18.9 0.0 1.9 1 1 0 1 1 1 1 Elongation Factor G, domain II RF3_C PF16658.5 AIM23244.1 - 0.046 13.5 0.0 0.093 12.6 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain DUF2975 PF11188.8 AIM23245.1 - 0.067 13.1 0.2 0.12 12.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) RseC_MucC PF04246.12 AIM23246.1 - 2.3e-35 121.4 0.1 2.7e-35 121.2 0.1 1.0 1 0 0 1 1 1 1 Positive regulator of sigma(E), RseC/MucC SNARE_assoc PF09335.11 AIM23246.1 - 0.13 12.8 1.7 0.2 12.1 1.5 1.4 1 1 0 1 1 1 0 SNARE associated Golgi protein MucB_RseB PF03888.14 AIM23247.1 - 1.7e-60 203.6 0.0 2.3e-60 203.2 0.0 1.1 1 0 0 1 1 1 1 MucB/RseB N-terminal domain MucB_RseB_C PF17188.4 AIM23247.1 - 3.5e-27 94.5 0.0 1.6e-26 92.4 0.0 1.9 2 0 0 2 2 2 1 MucB/RseB C-terminal domain LolA_like PF17131.4 AIM23247.1 - 5.8e-06 26.2 0.0 8.6e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Outer membrane lipoprotein-sorting protein RseA_N PF03872.13 AIM23248.1 - 1.2e-36 125.0 0.7 1.2e-36 125.0 0.7 2.1 2 0 0 2 2 2 1 Anti sigma-E protein RseA, N-terminal domain RseA_C PF03873.13 AIM23248.1 - 2.1e-23 82.3 2.0 2.1e-23 82.3 2.0 2.4 2 0 0 2 2 2 1 Anti sigma-E protein RseA, C-terminal domain Sigma70_r4_2 PF08281.12 AIM23249.1 - 2e-19 69.0 0.2 4.8e-19 67.8 0.2 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 AIM23249.1 - 3.8e-17 61.8 0.2 7.4e-17 60.9 0.2 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 AIM23249.1 - 6.4e-11 41.6 0.0 1.6e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 AIM23249.1 - 3.3e-08 33.7 0.1 8.5e-08 32.3 0.1 1.6 1 1 0 1 1 1 1 ECF sigma factor HTH_23 PF13384.6 AIM23249.1 - 0.00019 21.1 0.0 0.00053 19.7 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain FAD_binding_2 PF00890.24 AIM23250.1 - 4.8e-102 342.1 1.9 5.8e-102 341.9 1.9 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 AIM23250.1 - 4.8e-15 55.7 0.0 1.1e-14 54.6 0.0 1.5 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 AIM23250.1 - 8.2e-12 45.0 0.7 4.6e-07 29.4 0.2 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AIM23250.1 - 1.6e-08 34.5 6.5 1e-07 31.9 6.5 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AIM23250.1 - 0.00037 20.6 0.2 0.0012 19.0 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 AIM23250.1 - 0.00063 18.6 0.0 0.15 10.7 0.1 3.0 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_3 PF01494.19 AIM23250.1 - 0.0014 17.9 0.3 0.0031 16.8 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 AIM23250.1 - 0.0019 17.3 0.1 0.0032 16.6 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 AIM23250.1 - 0.0027 17.0 4.1 0.009 15.3 0.2 2.8 2 1 1 3 3 3 1 Thi4 family NAD_binding_7 PF13241.6 AIM23250.1 - 0.01 16.2 0.0 0.038 14.4 0.0 1.9 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 AIM23250.1 - 0.026 13.8 0.4 0.46 9.7 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 AIM23250.1 - 0.072 13.1 0.8 1.2 9.1 0.2 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding ApbA PF02558.16 AIM23250.1 - 0.13 11.9 0.1 0.25 11.0 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 AIM23250.1 - 0.16 11.1 3.1 2.1 7.3 3.1 2.1 1 1 0 1 1 1 0 Glucose inhibited division protein A MTS PF05175.14 AIM23251.1 - 4.9e-16 58.7 0.0 1.7e-15 57.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 AIM23251.1 - 1.4e-10 41.8 0.0 2.8e-10 40.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AIM23251.1 - 6.3e-10 39.0 0.0 7.4e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 AIM23251.1 - 2.1e-08 34.1 0.0 3.3e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.13 AIM23251.1 - 5.8e-07 29.2 0.0 9.1e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 AIM23251.1 - 1.2e-06 28.3 0.0 1.7e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_23 PF13489.6 AIM23251.1 - 5e-06 26.5 0.0 6.3e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 AIM23251.1 - 7.7e-06 26.5 0.0 3.3e-05 24.4 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain PCMT PF01135.19 AIM23251.1 - 0.00012 21.9 0.0 0.0002 21.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 AIM23251.1 - 0.0003 21.8 0.2 0.00059 20.8 0.2 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 AIM23251.1 - 0.0011 18.2 0.0 0.0017 17.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_10 PF05971.12 AIM23251.1 - 0.0012 18.3 0.0 0.0014 18.0 0.0 1.1 1 0 0 1 1 1 1 RNA methyltransferase Methyltransf_32 PF13679.6 AIM23251.1 - 0.0018 18.3 0.0 0.0026 17.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIM23251.1 - 0.0024 18.6 0.0 0.004 17.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 AIM23251.1 - 0.0068 16.3 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 AIM23251.1 - 0.018 14.9 0.0 0.025 14.4 0.0 1.2 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase CMAS PF02353.20 AIM23251.1 - 0.033 13.5 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 AIM23251.1 - 0.053 13.3 0.0 0.081 12.7 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase DUF938 PF06080.12 AIM23251.1 - 0.058 13.2 0.1 0.77 9.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF938) RrnaAD PF00398.20 AIM23251.1 - 0.08 12.0 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase N6_Mtase PF02384.16 AIM23251.1 - 0.13 11.5 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 N-6 DNA Methylase GidB PF02527.15 AIM23251.1 - 0.16 11.3 0.2 0.34 10.2 0.2 1.6 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_4 PF02390.17 AIM23251.1 - 0.18 11.3 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase DEAD PF00270.29 AIM23252.1 - 1.7e-45 154.9 0.1 4.2e-45 153.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AIM23252.1 - 3.2e-29 101.5 0.1 1e-27 96.6 0.1 2.6 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 AIM23252.1 - 3.3e-08 33.7 0.0 7.5e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 AIM23252.1 - 6.9e-05 23.2 0.2 0.00037 20.8 0.2 2.2 1 1 0 1 1 1 1 AAA domain SNF2_N PF00176.23 AIM23252.1 - 0.044 12.5 0.0 0.32 9.7 0.0 2.0 2 0 0 2 2 2 0 SNF2 family N-terminal domain AAA_22 PF13401.6 AIM23252.1 - 0.12 12.6 0.6 0.8 10.0 0.3 2.5 1 1 1 2 2 2 0 AAA domain CMS1 PF14617.6 AIM23252.1 - 0.26 10.6 0.0 0.26 10.6 0.0 3.0 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit Ank_2 PF12796.7 AIM23253.1 - 1.5e-20 73.5 1.4 9.7e-12 45.3 0.1 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 AIM23253.1 - 2.8e-16 59.6 2.2 1.4e-07 31.9 0.2 4.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 AIM23253.1 - 8e-16 56.6 0.6 0.0087 16.5 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 AIM23253.1 - 2.3e-12 46.8 9.4 0.00092 19.6 1.1 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 AIM23253.1 - 4.8e-12 45.9 10.6 1.9e-05 24.8 0.4 3.9 2 1 3 5 5 5 4 Ankyrin repeats (many copies) MC1 PF05854.11 AIM23253.1 - 0.0076 16.5 0.3 0.029 14.7 0.0 1.9 2 0 0 2 2 2 1 Non-histone chromosomal protein MC1 DUF2974 PF11187.8 AIM23254.1 - 7.6e-05 22.4 1.4 0.00012 21.8 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 AIM23254.1 - 0.00028 21.6 0.6 0.00036 21.2 0.6 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 AIM23254.1 - 0.0084 15.6 0.9 0.012 15.1 0.9 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Glycos_transf_1 PF00534.20 AIM23254.1 - 0.018 14.6 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferases group 1 Lipase_3 PF01764.25 AIM23254.1 - 0.051 13.4 6.3 0.2 11.5 3.8 2.2 1 1 1 2 2 2 0 Lipase (class 3) Chlorophyllase2 PF12740.7 AIM23254.1 - 0.087 11.7 0.1 0.13 11.1 0.1 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Nod_GRP PF07806.11 AIM23254.1 - 0.18 11.6 2.4 9.6 6.1 0.6 2.4 2 0 0 2 2 2 0 Nodule-specific GRP repeat Eno-Rase_NADH_b PF12242.8 AIM23254.1 - 0.2 11.4 1.0 0.4 10.5 1.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Gly_radical PF01228.21 AIM23255.1 - 1.2e-23 83.7 0.4 1.8e-23 83.1 0.0 1.4 2 0 0 2 2 2 1 Glycine radical UDG PF03167.19 AIM23256.1 - 5.8e-25 88.1 0.0 7.8e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily GrpE PF01025.19 AIM23257.1 - 3.6e-49 166.6 0.8 4.2e-49 166.4 0.8 1.0 1 0 0 1 1 1 1 GrpE V-ATPase_G_2 PF16999.5 AIM23257.1 - 0.062 13.7 8.2 0.13 12.7 8.2 1.5 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit DUF211 PF02680.14 AIM23257.1 - 0.069 13.3 0.0 0.15 12.2 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized ArCR, COG1888 PKcGMP_CC PF16808.5 AIM23257.1 - 0.11 12.4 1.5 0.22 11.4 0.3 2.1 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Band_7 PF01145.25 AIM23257.1 - 1 9.3 3.7 13 5.7 3.5 2.0 1 1 0 1 1 1 0 SPFH domain / Band 7 family NAD_kinase PF01513.21 AIM23258.1 - 1.3e-74 251.1 0.0 1.8e-74 250.6 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase SMC_N PF02463.19 AIM23259.1 - 3e-19 69.3 0.0 4.8e-19 68.7 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AIM23259.1 - 1.7e-18 67.8 6.3 4.3e-16 60.0 6.3 2.4 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AIM23259.1 - 8.3e-06 25.5 0.1 6.1e-05 22.7 0.0 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_15 PF13175.6 AIM23259.1 - 0.00013 21.9 0.0 0.00028 20.7 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 AIM23259.1 - 0.0004 20.3 0.0 0.54 10.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 AIM23259.1 - 0.0026 18.3 2.0 0.63 10.5 0.0 3.3 2 1 0 2 2 2 1 ABC transporter AAA_22 PF13401.6 AIM23259.1 - 0.02 15.2 7.8 0.085 13.1 0.0 4.1 3 1 0 3 3 3 0 AAA domain IIGP PF05049.13 AIM23259.1 - 0.25 10.4 1.6 2.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) SmpA_OmlA PF04355.13 AIM23260.1 - 1.4e-27 95.3 0.9 1.7e-27 95.0 0.9 1.1 1 0 0 1 1 1 1 SmpA / OmlA family Ub-RnfH PF03658.14 AIM23261.1 - 2.2e-34 117.7 0.1 2.6e-34 117.4 0.1 1.1 1 0 0 1 1 1 1 RnfH family Ubiquitin Polyketide_cyc PF03364.20 AIM23262.1 - 2.5e-32 111.8 0.0 2.9e-32 111.6 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 AIM23262.1 - 1.9e-10 41.2 0.0 2.2e-10 40.9 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF1857 PF08982.11 AIM23262.1 - 0.018 14.9 0.0 0.022 14.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1857) SmpB PF01668.18 AIM23263.1 - 2e-57 193.1 0.1 2.3e-57 192.9 0.1 1.0 1 0 0 1 1 1 1 SmpB protein Biotin_lipoyl_2 PF13533.6 AIM23264.1 - 4.8e-07 29.5 6.1 1.5e-06 27.9 0.0 3.3 3 0 0 3 3 3 1 Biotin-lipoyl like HlyD_D23 PF16576.5 AIM23264.1 - 8.2e-07 28.5 4.7 9.5e-06 25.0 1.6 2.2 1 1 0 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AIM23264.1 - 1.4e-06 28.9 0.4 0.00034 21.3 0.1 2.7 2 0 0 2 2 2 1 HlyD family secretion protein HlyD PF00529.20 AIM23264.1 - 4.6e-06 26.4 0.2 8e-06 25.6 0.2 1.4 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS DUF4407 PF14362.6 AIM23264.1 - 0.008 15.6 9.6 0.008 15.6 9.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4407) Fez1 PF06818.15 AIM23264.1 - 0.055 13.9 5.8 0.082 13.4 5.8 1.2 1 0 0 1 1 1 0 Fez1 TMF_DNA_bd PF12329.8 AIM23264.1 - 0.062 13.3 0.9 4.9 7.2 0.0 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF1664 PF07889.12 AIM23264.1 - 0.14 12.2 1.3 0.27 11.3 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) T3SS_needle_E PF08988.10 AIM23264.1 - 0.18 12.0 10.2 0.36 11.0 0.3 3.2 3 0 0 3 3 3 0 Type III secretion system, cytoplasmic E component of needle Filament PF00038.21 AIM23264.1 - 0.46 10.0 7.8 0.35 10.4 6.0 1.6 1 1 0 1 1 1 0 Intermediate filament protein Spc7 PF08317.11 AIM23264.1 - 0.69 8.7 6.8 1.7 7.4 5.5 1.7 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF3584 PF12128.8 AIM23264.1 - 1.1 6.7 9.0 1.6 6.1 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TBCA PF02970.16 AIM23264.1 - 2.2 8.7 5.3 1.2 9.6 0.2 2.4 1 1 1 2 2 2 0 Tubulin binding cofactor A HrpB7 PF09486.10 AIM23264.1 - 2.3 8.6 20.6 5 7.5 6.5 2.3 1 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) OmpH PF03938.14 AIM23264.1 - 5.8 7.2 17.4 3.5e+02 1.5 17.4 2.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) KfrA_N PF11740.8 AIM23264.1 - 7.7 7.2 16.5 1.6 9.4 4.3 3.2 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term TPR_MLP1_2 PF07926.12 AIM23264.1 - 8.5 6.4 15.2 1.2 9.2 1.0 2.5 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3302 PF11742.8 AIM23265.1 - 9.8e-39 131.4 6.0 1.2e-38 131.1 6.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3302) DUF1192 PF06698.11 AIM23265.1 - 0.0062 16.6 0.3 0.01 15.8 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1192) DUF998 PF06197.13 AIM23265.1 - 0.015 14.9 1.0 0.021 14.4 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF998) DUF3810 PF12725.7 AIM23265.1 - 0.19 11.0 0.0 0.21 10.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF3313 PF11769.8 AIM23266.1 - 8e-45 152.9 0.2 9.3e-45 152.7 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3313) CcmF_C PF16327.5 AIM23266.1 - 0.014 14.7 0.1 0.021 14.1 0.1 1.3 1 0 0 1 1 1 0 Cytochrome c-type biogenesis protein CcmF C-terminal LysR_substrate PF03466.20 AIM23267.1 - 2.7e-27 95.5 0.1 3.5e-27 95.2 0.1 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM23267.1 - 1.8e-16 59.8 0.9 3.2e-16 59.0 0.9 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_20 PF12840.7 AIM23267.1 - 0.00013 21.9 0.6 0.00046 20.2 0.3 2.1 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_IclR PF09339.10 AIM23267.1 - 0.0098 15.7 3.0 0.048 13.5 0.4 2.8 3 0 0 3 3 3 1 IclR helix-turn-helix domain PepSY_TM PF03929.16 AIM23268.1 - 7.4e-64 216.2 13.0 1.2e-63 215.5 13.0 1.3 1 0 0 1 1 1 1 PepSY-associated TM region DUF2534 PF10749.9 AIM23268.1 - 7.3e-27 93.4 0.7 1.5e-26 92.4 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2534) DUF4079 PF13301.6 AIM23268.1 - 0.00018 21.6 0.0 2.8 8.1 0.3 4.0 3 1 0 4 4 4 2 Protein of unknown function (DUF4079) MHYT PF03707.16 AIM23268.1 - 1.9 8.7 0.0 1.9 8.7 0.0 4.3 5 1 0 5 5 5 0 Bacterial signalling protein N terminal repeat DUF2946 PF11162.8 AIM23269.1 - 2.6e-13 50.6 11.5 3e-13 50.4 11.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2946) Acetyltransf_1 PF00583.25 AIM23270.1 - 1.8e-09 37.8 0.0 2.3e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AIM23270.1 - 9.8e-09 35.5 0.0 1.3e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AIM23270.1 - 1e-06 28.7 0.0 1.3e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AIM23270.1 - 0.0022 18.1 0.0 0.004 17.2 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 AIM23270.1 - 0.0035 17.3 0.0 0.0054 16.7 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 AIM23270.1 - 0.0088 16.1 0.0 0.012 15.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 AIM23270.1 - 0.025 14.3 0.0 0.037 13.8 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_4 PF13420.7 AIM23270.1 - 0.03 14.5 0.0 0.032 14.4 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Methyltransf_11 PF08241.12 AIM23271.1 - 1.6e-21 76.8 0.0 2.4e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AIM23271.1 - 1e-19 71.0 0.0 1.5e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AIM23271.1 - 2.2e-15 56.9 0.0 2.9e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AIM23271.1 - 2.2e-14 53.5 0.0 2.9e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIM23271.1 - 9.9e-14 51.9 0.0 1.5e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AIM23271.1 - 7.9e-08 31.9 0.0 1.1e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 AIM23271.1 - 3e-07 29.7 0.0 4.1e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 AIM23271.1 - 6.2e-07 29.0 0.0 8.8e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 AIM23271.1 - 2.8e-05 23.7 0.0 4.7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 AIM23271.1 - 4.1e-05 23.1 0.0 5.9e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 AIM23271.1 - 0.00051 20.1 0.0 0.0007 19.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 AIM23271.1 - 0.0056 16.2 0.0 0.02 14.4 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_2 PF00891.18 AIM23271.1 - 0.0065 15.8 0.0 0.0091 15.3 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain ADH_zinc_N PF00107.26 AIM23271.1 - 0.0069 16.4 0.0 0.014 15.4 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase FtsJ PF01728.19 AIM23271.1 - 0.007 16.5 0.0 0.025 14.7 0.0 1.8 1 1 0 1 1 1 1 FtsJ-like methyltransferase ADH_zinc_N_2 PF13602.6 AIM23271.1 - 0.0084 17.2 0.0 0.014 16.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase RcsF PF16358.5 AIM23271.1 - 0.019 15.0 0.0 0.031 14.3 0.0 1.3 1 0 0 1 1 1 0 RcsF lipoprotein Methyltransf_18 PF12847.7 AIM23271.1 - 0.074 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Acetyltransf_1 PF00583.25 AIM23272.1 - 1.7e-18 66.9 0.0 2.2e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AIM23272.1 - 1.1e-08 35.4 0.0 2.5e-08 34.2 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AIM23272.1 - 1.3e-07 31.6 0.0 1.7e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AIM23272.1 - 0.00019 21.3 0.0 0.00028 20.8 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 AIM23272.1 - 0.0067 16.6 0.0 0.0081 16.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 AIM23272.1 - 0.024 14.3 0.0 0.23 11.1 0.0 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AIM23272.1 - 0.024 14.7 0.0 0.045 13.9 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_6 PF13480.7 AIM23272.1 - 0.029 14.5 0.0 0.044 13.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 AIM23272.1 - 0.062 12.7 0.0 0.065 12.7 0.0 1.1 1 0 0 1 1 1 0 Putative acetyl-transferase DUF1543 PF07566.12 AIM23273.1 - 8.7e-36 121.4 2.7 2.7e-18 65.4 0.0 2.1 2 0 0 2 2 2 2 Domain of Unknown Function (DUF1543) DUF2158 PF09926.9 AIM23274.1 - 1.4e-06 27.9 0.1 1.7e-06 27.6 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized small protein (DUF2158) Acetyltransf_CG PF14542.6 AIM23275.1 - 3.1e-22 78.5 0.0 3.5e-22 78.3 0.0 1.0 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_1 PF00583.25 AIM23275.1 - 3e-06 27.5 0.0 3.2e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AIM23275.1 - 0.00015 21.7 0.0 0.00015 21.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AIM23275.1 - 0.00017 21.9 0.0 0.0002 21.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AIM23275.1 - 0.062 13.4 0.0 0.41 10.7 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 AIM23275.1 - 0.13 12.3 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_13 PF13880.6 AIM23275.1 - 0.19 11.8 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Fer4_19 PF06902.11 AIM23276.1 - 2.4e-27 94.8 0.1 2.7e-27 94.6 0.1 1.0 1 0 0 1 1 1 1 Divergent 4Fe-4S mono-cluster DoxX PF07681.12 AIM23277.1 - 1.2e-16 61.1 14.0 1.2e-16 61.1 14.0 1.5 2 0 0 2 2 2 1 DoxX SURF4 PF02077.15 AIM23277.1 - 2.9e-09 36.9 8.7 7.3e-09 35.6 8.7 1.6 1 1 0 1 1 1 1 SURF4 family DoxD PF04173.13 AIM23277.1 - 9.7e-05 22.3 3.9 9.7e-05 22.3 3.9 2.1 1 1 1 2 2 2 1 TQO small subunit DoxD TMEM101 PF15111.6 AIM23277.1 - 0.0032 17.1 3.6 0.0052 16.4 3.6 1.4 1 1 0 1 1 1 1 TMEM101 protein family DoxX_2 PF13564.6 AIM23277.1 - 0.0084 16.2 11.6 0.0084 16.2 11.6 1.5 1 1 1 2 2 2 1 DoxX-like family DUF1700 PF08006.11 AIM23277.1 - 3 7.3 14.4 0.14 11.7 8.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1700) DUF417 PF04224.12 AIM23277.1 - 4.4 6.8 12.9 7.1 6.2 1.0 2.1 1 1 0 2 2 2 0 Protein of unknown function, DUF417 Smr PF01713.21 AIM23278.1 - 4.1e-18 65.5 0.0 7.3e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 Smr domain NEL PF14496.6 AIM23278.1 - 0.028 13.8 0.5 0.63 9.4 0.0 2.1 2 0 0 2 2 2 0 C-terminal novel E3 ligase, LRR-interacting MbeD_MobD PF04899.12 AIM23279.1 - 2.9e-09 36.9 14.1 5.2e-09 36.1 12.6 1.9 1 1 1 2 2 2 1 MbeD/MobD like tRNA_bind_3 PF17176.4 AIM23279.1 - 0.004 17.4 3.5 0.0051 17.1 3.5 1.3 1 0 0 1 1 1 1 tRNA-binding domain DUF3150 PF11348.8 AIM23279.1 - 0.0054 16.0 3.0 0.006 15.8 3.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3150) PDDEXK_6 PF04720.12 AIM23279.1 - 0.02 14.8 2.0 0.022 14.7 2.0 1.1 1 0 0 1 1 1 0 PDDEXK-like family of unknown function YabA PF06156.13 AIM23279.1 - 0.026 15.1 4.9 0.071 13.8 4.8 1.8 1 1 0 1 1 1 0 Initiation control protein YabA CENP-H PF05837.12 AIM23279.1 - 0.029 14.8 7.3 0.043 14.2 7.3 1.4 1 1 0 1 1 1 0 Centromere protein H (CENP-H) DCB PF16213.5 AIM23279.1 - 0.043 13.5 0.6 0.047 13.4 0.6 1.3 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 Bacillus_HBL PF05791.11 AIM23279.1 - 0.044 13.6 3.8 0.49 10.2 1.6 2.0 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) ArlS_N PF18719.1 AIM23279.1 - 0.045 14.0 0.8 0.047 13.9 0.8 1.2 1 0 0 1 1 1 0 ArlS sensor domain ATP-synt_E PF05680.12 AIM23279.1 - 0.045 14.1 4.5 0.052 13.9 4.1 1.3 1 1 0 1 1 1 0 ATP synthase E chain DUF4449 PF14613.6 AIM23279.1 - 0.056 13.6 2.1 0.062 13.4 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) TPR_MLP1_2 PF07926.12 AIM23279.1 - 0.17 11.9 15.5 0.15 12.1 11.5 2.0 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DegS PF05384.11 AIM23279.1 - 0.18 11.3 6.9 0.35 10.3 6.9 1.5 1 1 0 1 1 1 0 Sensor protein DegS HHH_9 PF17674.1 AIM23279.1 - 0.2 12.6 2.0 5.3 8.0 0.9 2.2 1 1 1 2 2 2 0 HHH domain DUF572 PF04502.13 AIM23279.1 - 0.22 11.1 5.1 0.23 11.1 5.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF2205 PF10224.9 AIM23279.1 - 0.23 11.5 8.8 2.8 8.0 5.3 2.2 1 1 1 2 2 2 0 Short coiled-coil protein Bap31_Bap29_C PF18035.1 AIM23279.1 - 0.25 11.3 9.1 2.6 8.1 5.7 2.5 1 1 1 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain PI3K_P85_iSH2 PF16454.5 AIM23279.1 - 0.32 10.6 9.7 3.4 7.3 9.7 2.0 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain CENP-Q PF13094.6 AIM23279.1 - 0.32 11.2 10.7 0.47 10.6 10.7 1.3 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit ADIP PF11559.8 AIM23279.1 - 0.52 10.4 11.3 0.51 10.4 9.9 1.6 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding RmuC PF02646.16 AIM23279.1 - 0.53 9.4 8.9 1 8.5 5.3 2.0 1 1 1 2 2 2 0 RmuC family FUSC PF04632.12 AIM23279.1 - 0.88 8.0 8.3 0.98 7.9 8.3 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3450 PF11932.8 AIM23279.1 - 0.92 8.8 10.9 0.92 8.8 10.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Exonuc_VII_L PF02601.15 AIM23279.1 - 1.1 8.7 7.9 1.2 8.6 7.9 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Nbl1_Borealin_N PF10444.9 AIM23279.1 - 1.5 8.5 7.1 0.97 9.1 0.9 2.5 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal TolA_bind_tri PF16331.5 AIM23279.1 - 1.6 8.9 14.6 7.2 6.8 11.6 2.7 1 1 1 2 2 2 0 TolA binding protein trimerisation OmpH PF03938.14 AIM23279.1 - 2 8.7 13.6 3.1 8.1 13.6 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DivIC PF04977.15 AIM23279.1 - 2.2 8.1 8.3 3.4 7.5 6.7 2.0 1 1 1 2 2 2 0 Septum formation initiator DUF1198 PF06711.11 AIM23280.1 - 5.9e-56 188.5 0.8 6.6e-56 188.4 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1198) DUF2002 PF09400.10 AIM23281.1 - 4.7e-56 187.5 0.6 5.2e-56 187.4 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2002) MFS_1 PF07690.16 AIM23282.1 - 5e-28 98.0 57.7 1.5e-14 53.7 38.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 AIM23282.1 - 6.6e-06 25.2 18.7 4.9e-05 22.4 11.5 2.2 2 0 0 2 2 2 2 MFS_1 like family LysR_substrate PF03466.20 AIM23283.1 - 7.6e-42 143.0 10.8 9.1e-42 142.8 10.1 1.5 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AIM23283.1 - 8.4e-19 67.3 3.0 1.6e-18 66.4 3.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MFS_1 PF07690.16 AIM23284.1 - 3.5e-48 164.3 42.2 3.5e-48 164.3 42.2 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 AIM23284.1 - 0.026 13.0 12.4 0.0046 15.4 5.7 2.1 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 AIM23284.1 - 0.032 13.1 19.5 0.042 12.7 6.1 3.6 2 1 2 4 4 4 0 Sugar (and other) transporter DUF4440 PF14534.6 AIM23285.1 - 9.6e-06 26.0 0.0 1e-05 25.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 AIM23285.1 - 0.0043 17.7 0.0 0.0055 17.3 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF2574 PF10836.8 AIM23287.1 - 0.0068 16.3 0.5 0.0081 16.0 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2574) RR_TM4-6 PF06459.12 AIM23287.1 - 0.92 9.3 13.9 1 9.1 13.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 AIM23287.1 - 1.5 7.5 10.4 1.6 7.4 10.4 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 AIM23287.1 - 1.9 7.6 6.2 1.9 7.7 6.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Connexin PF00029.19 AIM23287.1 - 2.1 8.0 4.7 2.2 8.0 4.7 1.3 1 0 0 1 1 1 0 Connexin Neur_chan_memb PF02932.16 AIM23287.1 - 4 7.4 7.2 4.1 7.4 7.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Endostatin PF06482.11 AIM23287.1 - 6.3 6.2 9.5 7.1 6.0 9.5 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF883 PF05957.13 AIM23288.1 - 2.6e-25 88.8 0.9 3.1e-25 88.6 0.9 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 AIM23288.1 - 0.0053 17.3 10.4 0.099 13.2 1.1 2.7 2 1 0 2 2 2 2 YtxH-like protein Apolipoprotein PF01442.18 AIM23288.1 - 0.014 15.3 2.2 0.022 14.7 2.1 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain ASL_C PF08328.11 AIM23288.1 - 0.043 13.9 0.1 0.047 13.8 0.1 1.1 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal KxDL PF10241.9 AIM23288.1 - 0.06 13.6 0.2 0.098 12.9 0.1 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein DUF543 PF04418.12 AIM23288.1 - 0.12 12.4 0.8 0.16 12.0 0.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF543) Aminotran_1_2 PF00155.21 AIM23289.1 - 1.2e-21 77.4 0.0 1.6e-21 76.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II GntR PF00392.21 AIM23289.1 - 8e-19 67.1 0.1 2.8e-18 65.3 0.1 2.0 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_41 PF14502.6 AIM23289.1 - 0.00054 19.6 0.0 0.0019 17.9 0.0 2.0 3 0 0 3 3 3 1 Helix-turn-helix domain CMD PF02627.20 AIM23290.1 - 1.4e-20 73.1 0.5 4.4e-19 68.3 0.1 2.1 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family TAL_effector PF03377.13 AIM23290.1 - 0.12 12.7 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 TAL effector repeat Glutaredoxin PF00462.24 AIM23291.1 - 1.3e-15 57.3 0.0 1.5e-15 57.1 0.0 1.0 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 AIM23291.1 - 0.00073 19.9 0.0 0.00089 19.6 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) GST_N PF02798.20 AIM23291.1 - 0.031 14.6 0.0 0.036 14.4 0.0 1.1 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_3 PF13192.6 AIM23291.1 - 0.048 13.7 0.0 0.06 13.4 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_9 PF14595.6 AIM23291.1 - 0.076 12.8 0.0 0.079 12.7 0.0 1.0 1 0 0 1 1 1 0 Thioredoxin Flavodoxin_NdrI PF07972.11 AIM23292.1 - 1.5e-46 157.5 0.0 1.7e-46 157.3 0.0 1.0 1 0 0 1 1 1 1 NrdI Flavodoxin like Ribonuc_red_lgC PF02867.15 AIM23293.1 - 4.9e-146 487.3 0.2 5e-144 480.7 0.1 2.6 2 1 0 2 2 2 1 Ribonucleotide reductase, barrel domain RNR_N PF08343.10 AIM23293.1 - 2.7e-33 113.9 6.8 6.7e-33 112.6 6.8 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase N-terminal Ribonuc_red_lgN PF00317.21 AIM23293.1 - 1.7e-12 47.2 0.1 4.5e-12 45.8 0.1 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain Ribonuc_red_sm PF00268.21 AIM23294.1 - 1.7e-87 293.5 0.0 1.9e-87 293.3 0.0 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain N6_N4_Mtase PF01555.18 AIM23294.1 - 0.025 14.3 0.0 0.036 13.8 0.0 1.2 1 0 0 1 1 1 0 DNA methylase ParE_toxin PF05016.15 AIM23295.1 - 3.7e-12 46.7 0.4 4e-12 46.6 0.4 1.0 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE RHH_1 PF01402.21 AIM23296.1 - 0.00074 19.4 0.0 0.0018 18.1 0.0 1.7 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family RelB PF04221.12 AIM23296.1 - 0.012 15.6 0.1 0.017 15.1 0.1 1.5 1 1 0 1 1 1 0 RelB antitoxin PGK PF00162.19 AIM23296.1 - 0.013 14.5 0.0 0.014 14.4 0.0 1.0 1 0 0 1 1 1 0 Phosphoglycerate kinase HicB PF05534.12 AIM23296.1 - 0.025 14.4 0.0 0.068 13.0 0.0 1.7 2 0 0 2 2 2 0 HicB family RNase_E_G PF10150.9 AIM23296.1 - 0.029 13.8 0.2 0.031 13.7 0.2 1.1 1 0 0 1 1 1 0 Ribonuclease E/G family Arc PF03869.14 AIM23296.1 - 0.082 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Arc-like DNA binding domain DUF1289 PF06945.13 AIM23297.1 - 5.5e-19 67.7 5.3 6.3e-19 67.5 5.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1289) adh_short_C2 PF13561.6 AIM23298.1 - 9.2e-64 215.2 1.3 1e-63 215.0 1.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AIM23298.1 - 5.7e-54 182.5 0.2 7.2e-54 182.2 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AIM23298.1 - 7.3e-18 65.1 0.5 9.1e-18 64.8 0.5 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AIM23298.1 - 1.2e-07 31.5 0.0 5e-07 29.4 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 AIM23298.1 - 0.013 15.3 1.7 0.024 14.5 1.5 1.6 1 1 0 1 1 1 0 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 AIM23298.1 - 0.057 12.8 0.1 0.12 11.8 0.0 1.6 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase LytR_C PF13399.6 AIM23298.1 - 0.17 12.9 2.1 0.4 11.7 0.4 2.2 2 0 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator Lactamase_B PF00753.27 AIM23299.1 - 3.8e-23 82.5 0.6 6.4e-23 81.8 0.6 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AIM23299.1 - 0.0014 18.2 0.1 0.0023 17.5 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 AIM23299.1 - 0.014 15.3 0.0 0.055 13.4 0.0 1.8 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Cas_Csy4 PF09618.10 AIM23299.1 - 0.067 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) Lactamase_B_6 PF16661.5 AIM23299.1 - 0.16 11.4 0.0 10 5.5 0.0 2.2 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily domain Patatin PF01734.22 AIM23300.1 - 4.6e-24 85.7 0.3 6.4e-24 85.3 0.3 1.2 1 0 0 1 1 1 1 Patatin-like phospholipase L-fibroin PF05849.11 AIM23300.1 - 0.052 12.8 0.3 0.25 10.6 0.3 1.9 1 1 0 1 1 1 0 Fibroin light chain (L-fibroin) 2HCT PF03390.15 AIM23301.1 - 3.7e-141 470.5 37.0 4.3e-141 470.3 37.0 1.0 1 0 0 1 1 1 1 2-hydroxycarboxylate transporter family sCache_3_2 PF17203.4 AIM23302.1 - 1.5e-19 70.5 0.3 3.1e-19 69.5 0.3 1.5 1 0 0 1 1 1 1 Single cache domain 3 HATPase_c PF02518.26 AIM23302.1 - 3.4e-15 56.5 0.0 7.1e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AIM23302.1 - 9.5e-14 51.1 0.0 2.2e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 GHKL domain SPOB_a PF14689.6 AIM23302.1 - 3.3e-05 23.5 0.3 7.9e-05 22.3 0.3 1.7 1 0 0 1 1 1 1 Sensor_kinase_SpoOB-type, alpha-helical domain HATPase_c_2 PF13581.6 AIM23302.1 - 0.00022 21.2 0.1 0.00096 19.1 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain PAS_8 PF13188.7 AIM23302.1 - 0.00023 21.1 0.0 0.0005 20.0 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 AIM23302.1 - 0.00046 20.2 0.0 0.0011 19.0 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_7 PF12860.7 AIM23302.1 - 0.00079 19.6 0.0 0.0029 17.7 0.0 2.0 1 1 0 1 1 1 1 PAS fold dCache_3 PF14827.6 AIM23302.1 - 0.0017 18.1 0.1 0.0083 15.8 0.1 2.0 1 1 0 1 1 1 1 Double sensory domain of two-component sensor kinase PAS_9 PF13426.7 AIM23302.1 - 0.003 17.8 0.0 0.018 15.3 0.0 2.3 2 1 0 2 2 2 1 PAS domain PAS_4 PF08448.10 AIM23302.1 - 0.016 15.4 0.0 0.14 12.4 0.0 2.3 2 0 0 2 2 2 0 PAS fold PriA_3primeBD PF17764.1 AIM23302.1 - 0.023 14.6 0.0 0.45 10.5 0.0 2.4 2 0 0 2 2 2 0 3′ DNA-binding domain (3′BD) HATPase_c_3 PF13589.6 AIM23302.1 - 0.04 13.8 0.0 0.079 12.8 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_10 PF13596.6 AIM23302.1 - 0.14 12.8 0.0 1.2 9.7 0.0 2.4 1 1 1 2 2 2 0 PAS domain Response_reg PF00072.24 AIM23303.1 - 1.7e-21 76.5 0.0 2.8e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain CitT PF12431.8 AIM23303.1 - 2.3e-05 24.6 0.0 4.7e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulator HTH_DeoR PF08220.12 AIM23303.1 - 0.007 16.1 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_IclR PF09339.10 AIM23303.1 - 0.018 14.8 0.0 0.041 13.7 0.0 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain ABC_tran PF00005.27 AIM23304.1 - 2.8e-34 118.6 0.0 4.5e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter CBS PF00571.28 AIM23304.1 - 2.2e-10 40.8 0.0 1.3e-05 25.5 0.0 2.9 2 0 0 2 2 2 2 CBS domain AAA_21 PF13304.6 AIM23304.1 - 3.6e-06 27.0 0.7 0.0038 17.1 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AIM23304.1 - 6.3e-05 23.4 0.3 0.00021 21.7 0.2 2.0 2 1 0 2 2 2 1 AAA ATPase domain ABC_ATPase PF09818.9 AIM23304.1 - 0.00037 19.4 0.3 0.2 10.4 0.1 2.1 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 AIM23304.1 - 0.0011 18.7 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AIM23304.1 - 0.0012 19.2 0.6 0.017 15.4 0.6 2.3 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AIM23304.1 - 0.0067 16.3 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 AIM23304.1 - 0.01 15.3 0.4 1.2 8.6 0.0 2.1 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 AIM23304.1 - 0.013 16.0 0.1 0.039 14.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AIM23304.1 - 0.014 15.1 0.1 0.039 13.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 AIM23304.1 - 0.015 15.4 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 AIM23304.1 - 0.032 14.4 0.1 0.054 13.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.20 AIM23304.1 - 0.033 14.1 0.0 0.061 13.2 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase BCA_ABC_TP_C PF12399.8 AIM23304.1 - 0.046 13.7 0.1 0.097 12.6 0.1 1.6 1 0 0 1 1 1 0 Branched-chain amino acid ATP-binding cassette transporter SbcCD_C PF13558.6 AIM23304.1 - 0.064 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 AIM23304.1 - 0.07 12.4 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF87 PF01935.17 AIM23304.1 - 0.11 12.5 0.1 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_23 PF13476.6 AIM23304.1 - 0.13 12.7 0.1 0.31 11.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain BPD_transp_1 PF00528.22 AIM23305.1 - 5.8e-27 94.6 12.9 5.8e-27 94.6 12.9 2.2 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OpuAC PF04069.12 AIM23306.1 - 3.5e-55 187.4 3.7 4.4e-55 187.0 3.7 1.0 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system LysR_substrate PF03466.20 AIM23307.1 - 7.4e-42 143.1 1.2 1.2e-41 142.4 1.2 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM23307.1 - 1.9e-24 85.4 1.6 6.4e-24 83.7 1.6 2.0 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_20 PF12840.7 AIM23307.1 - 0.037 14.1 0.1 0.14 12.2 0.1 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_30 PF13556.6 AIM23307.1 - 0.048 13.5 0.1 0.13 12.1 0.1 1.7 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain MFS_1 PF07690.16 AIM23308.1 - 6.1e-42 143.8 77.1 4.8e-30 104.7 46.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AIM23308.1 - 6.6e-14 51.6 14.7 6.6e-14 51.6 14.7 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 AIM23308.1 - 6e-05 22.5 38.9 0.00023 20.6 38.9 1.9 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB AzlC PF03591.14 AIM23309.1 - 4.1e-38 130.9 11.1 4.1e-38 130.9 11.1 1.9 2 0 0 2 2 2 1 AzlC protein AzlD PF05437.12 AIM23310.1 - 2.8e-13 49.9 5.1 3.3e-13 49.6 5.1 1.1 1 0 0 1 1 1 1 Branched-chain amino acid transport protein (AzlD) MarR PF01047.22 AIM23311.1 - 1.5e-16 60.1 0.2 3.8e-16 58.7 0.2 1.7 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 AIM23311.1 - 3.5e-10 39.6 0.2 1.1e-09 38.0 0.1 1.9 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 AIM23311.1 - 3e-05 24.4 0.1 0.00011 22.6 0.0 1.9 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_Crp_2 PF13545.6 AIM23311.1 - 7.4e-05 22.6 0.9 0.00014 21.8 0.1 1.9 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_34 PF13601.6 AIM23311.1 - 0.00076 19.6 0.0 0.0015 18.7 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_24 PF13412.6 AIM23311.1 - 0.0014 18.1 0.0 0.0027 17.2 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding TrmB PF01978.19 AIM23311.1 - 0.0015 18.3 0.0 0.0025 17.7 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.10 AIM23311.1 - 0.0037 17.0 0.0 0.0077 16.0 0.0 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain SgrR_N PF12793.7 AIM23311.1 - 0.015 15.5 0.1 0.033 14.4 0.1 1.7 1 1 0 1 1 1 0 Sugar transport-related sRNA regulator N-term Rrf2 PF02082.20 AIM23311.1 - 0.019 15.3 0.1 0.057 13.8 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator RP-C PF03428.13 AIM23311.1 - 0.061 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Replication protein C N-terminal domain AbiEi_4 PF13338.6 AIM23311.1 - 0.064 13.4 0.1 0.12 12.5 0.1 1.5 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin BAG PF02179.16 AIM23311.1 - 0.078 13.4 1.4 2.6 8.5 0.2 2.3 2 0 0 2 2 2 0 BAG domain Dyp_perox PF04261.12 AIM23311.1 - 0.11 11.5 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Dyp-type peroxidase family HTH_36 PF13730.6 AIM23311.1 - 0.14 12.2 0.0 0.34 10.9 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain OEP PF02321.18 AIM23312.1 - 1.9e-44 151.7 51.6 8.8e-27 94.1 25.7 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein HlyD_3 PF13437.6 AIM23313.1 - 7.8e-17 61.9 3.9 1.3e-12 48.3 0.8 2.9 2 2 0 2 2 2 2 HlyD family secretion protein HlyD PF00529.20 AIM23313.1 - 4.1e-16 58.6 0.0 6.5e-16 58.0 0.0 1.3 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS HlyD_D23 PF16576.5 AIM23313.1 - 2e-14 53.3 7.5 5.2e-13 48.7 7.5 2.2 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 AIM23313.1 - 3e-10 39.8 0.2 3e-10 39.8 0.2 3.6 4 0 0 4 4 4 1 Biotin-lipoyl like Orf78 PF06024.12 AIM23313.1 - 0.00079 19.7 0.0 0.0023 18.2 0.0 1.8 1 0 0 1 1 1 1 Orf78 (ac78) Biotin_lipoyl PF00364.22 AIM23313.1 - 0.0028 17.4 0.1 0.64 9.9 0.0 2.5 2 0 0 2 2 2 1 Biotin-requiring enzyme CrgA PF06781.12 AIM23313.1 - 0.026 14.6 0.3 0.068 13.2 0.3 1.8 1 1 0 1 1 1 0 Cell division protein CrgA CCSMST1 PF15013.6 AIM23313.1 - 0.029 14.5 0.0 0.059 13.5 0.0 1.5 1 0 0 1 1 1 0 CCSMST1 family MacB_PCD PF12704.7 AIM23313.1 - 0.029 14.7 5.7 0.068 13.5 0.2 2.2 1 1 1 2 2 2 0 MacB-like periplasmic core domain Wzz PF02706.15 AIM23313.1 - 0.13 12.5 1.8 0.25 11.7 0.0 2.4 2 1 0 2 2 2 0 Chain length determinant protein Cupin_5 PF06172.11 AIM23313.1 - 0.18 12.0 0.1 18 5.5 0.0 2.4 2 0 0 2 2 2 0 Cupin superfamily (DUF985) DUF4398 PF14346.6 AIM23313.1 - 0.5 11.0 18.2 0.15 12.7 0.6 3.2 2 1 0 3 3 3 0 Domain of unknown function (DUF4398) DUF2564 PF10819.8 AIM23313.1 - 5.2 7.5 7.1 3.9 7.9 2.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2564) MFS_1 PF07690.16 AIM23314.1 - 1.3e-53 182.2 40.4 1.3e-53 182.2 40.4 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 AIM23314.1 - 3.9e-12 45.4 17.1 3.9e-12 45.4 17.1 2.3 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 AIM23314.1 - 2.6e-06 26.0 20.2 0.0029 16.0 0.4 3.8 3 1 1 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.6 AIM23314.1 - 0.0037 15.9 6.7 0.0037 15.9 6.7 3.5 3 1 0 3 3 3 2 MFS/sugar transport protein SpoU_methylase PF00588.19 AIM23315.1 - 5.9e-32 110.8 0.0 8.6e-32 110.3 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 AIM23315.1 - 6.5e-13 48.8 0.0 1.5e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding Thioredoxin PF00085.20 AIM23316.1 - 6.3e-27 93.6 0.0 9.8e-27 93.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 AIM23316.1 - 1.9e-10 41.1 0.0 7.2e-10 39.3 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 AIM23316.1 - 2e-06 28.0 0.0 0.0002 21.6 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like zinc_ribbon_4 PF13717.6 AIM23316.1 - 9.1e-06 25.5 0.5 2e-05 24.4 0.5 1.6 1 0 0 1 1 1 1 zinc-ribbon domain Redoxin PF08534.10 AIM23316.1 - 1.7e-05 24.6 0.0 6.1e-05 22.8 0.0 1.7 1 1 1 2 2 2 1 Redoxin Thioredoxin_9 PF14595.6 AIM23316.1 - 3.8e-05 23.5 0.0 4.8e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 AIM23316.1 - 4e-05 23.7 0.0 7.1e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 AIM23316.1 - 7.8e-05 22.2 0.0 8.9e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family TraF PF13728.6 AIM23316.1 - 0.00022 21.1 0.0 0.00028 20.8 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein HyaE PF07449.11 AIM23316.1 - 0.00024 21.0 0.0 0.00042 20.2 0.0 1.4 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE AhpC-TSA PF00578.21 AIM23316.1 - 0.002 18.0 0.0 0.0025 17.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_3 PF13192.6 AIM23316.1 - 0.0024 17.9 1.7 0.01 15.9 0.0 2.2 2 1 0 2 2 2 1 Thioredoxin domain zinc_ribbon_5 PF13719.6 AIM23316.1 - 0.028 14.2 1.3 0.082 12.7 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain TrbC_Ftype PF09673.10 AIM23316.1 - 0.093 12.8 0.0 0.11 12.5 0.0 1.3 1 1 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein Thioredoxin_6 PF13848.6 AIM23316.1 - 0.14 12.0 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain DTW PF03942.15 AIM23317.1 - 3.1e-44 151.1 0.0 3.6e-44 150.9 0.0 1.0 1 0 0 1 1 1 1 DTW domain ATP-grasp_5 PF13549.6 AIM23318.1 - 1.3e-74 250.4 0.2 2.5e-74 249.5 0.2 1.5 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 AIM23318.1 - 5.3e-46 155.8 0.2 1.1e-45 154.8 0.2 1.6 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 AIM23318.1 - 3.3e-21 76.0 0.0 2.3e-20 73.2 0.0 2.5 2 0 0 2 2 2 1 CoA binding domain Acetyltransf_1 PF00583.25 AIM23318.1 - 7e-12 45.6 0.1 3.1e-11 43.6 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 AIM23318.1 - 3.4e-09 37.5 0.0 1.1e-08 35.8 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AIM23318.1 - 2.6e-05 24.4 0.0 0.0012 19.0 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AIM23318.1 - 3e-05 24.0 0.0 8e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AIM23318.1 - 0.0032 17.9 0.0 0.0098 16.3 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AIM23318.1 - 0.041 13.9 0.0 0.16 11.9 0.0 2.0 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.6 AIM23318.1 - 0.048 13.8 0.1 0.22 11.6 0.0 2.2 2 0 0 2 2 1 0 GCN5-related N-acetyl-transferase CPSase_L_D2 PF02786.17 AIM23318.1 - 0.08 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Acetyltransf_6 PF13480.7 AIM23318.1 - 0.24 11.6 4.1 1.3 9.2 0.1 3.4 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain PLDc_2 PF13091.6 AIM23319.1 - 6.5e-28 97.3 0.0 1.2e-19 70.6 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 AIM23319.1 - 4.8e-13 48.7 0.5 4.6e-06 26.6 0.0 2.4 2 0 0 2 2 2 2 Phospholipase D Active site motif Sugar_tr PF00083.24 AIM23320.1 - 1.1e-38 133.2 32.5 3.3e-27 95.5 10.9 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 AIM23320.1 - 1.9e-24 86.2 43.5 9.2e-16 57.7 23.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 AIM23320.1 - 5.4e-11 41.7 27.8 1.7e-06 26.9 12.0 3.5 1 1 2 3 3 3 3 MFS/sugar transport protein MFS_1_like PF12832.7 AIM23320.1 - 3.3e-07 29.5 8.5 0.00013 20.9 3.9 3.4 2 2 1 3 3 3 3 MFS_1 like family Hydrolase_like PF13242.6 AIM23321.1 - 1.6e-13 50.5 0.0 2.6e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 AIM23321.1 - 4.7e-10 39.8 0.0 1e-06 28.9 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AIM23321.1 - 7.6e-09 36.2 0.0 3.4e-08 34.0 0.0 2.0 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase PNK3P PF08645.11 AIM23321.1 - 6.1e-07 29.3 0.0 7.8e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase Hydrolase_6 PF13344.6 AIM23321.1 - 0.00092 19.3 0.0 0.0018 18.4 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 AIM23321.1 - 0.12 12.8 0.1 0.36 11.2 0.0 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase ABC_tran PF00005.27 AIM23322.1 - 8e-36 123.6 0.0 1.7e-35 122.5 0.0 1.5 2 0 0 2 2 2 1 ABC transporter NIL PF09383.10 AIM23322.1 - 2.6e-19 68.8 0.0 5e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 NIL domain AAA_21 PF13304.6 AIM23322.1 - 2.7e-08 34.0 0.6 0.00028 20.8 0.0 2.5 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIM23322.1 - 1.7e-06 27.6 0.3 6.5e-06 25.7 0.3 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AIM23322.1 - 4.1e-05 23.9 0.5 0.00028 21.2 0.5 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AIM23322.1 - 0.0016 18.9 2.5 0.027 14.9 2.5 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AIM23322.1 - 0.009 15.7 0.1 0.019 14.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AIM23322.1 - 0.012 15.5 0.1 0.024 14.6 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase TniB PF05621.11 AIM23322.1 - 0.028 13.8 0.1 0.5 9.7 0.1 2.3 2 0 0 2 2 2 0 Bacterial TniB protein SbcCD_C PF13558.6 AIM23322.1 - 0.028 14.6 0.1 0.21 11.8 0.1 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 AIM23322.1 - 0.08 12.5 0.1 13 5.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 AIM23322.1 - 0.11 11.3 0.2 2.9 6.6 0.0 2.3 2 1 0 2 2 2 0 Predicted ATPase of the ABC class BPD_transp_1 PF00528.22 AIM23323.1 - 7e-22 78.1 18.0 7e-22 78.1 18.0 1.3 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component Lipoprotein_9 PF03180.14 AIM23324.1 - 7.7e-101 336.1 1.8 8.7e-101 336.0 1.8 1.0 1 0 0 1 1 1 1 NLPA lipoprotein OpuAC PF04069.12 AIM23324.1 - 2.3e-05 24.1 0.9 4e-05 23.3 0.9 1.6 1 1 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system Phosphonate-bd PF12974.7 AIM23324.1 - 0.0014 18.3 0.0 0.0041 16.8 0.0 1.7 2 0 0 2 2 2 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 AIM23324.1 - 0.0089 16.0 0.1 0.12 12.3 0.1 2.1 1 1 0 1 1 1 1 NMT1/THI5 like FMN_red PF03358.15 AIM23324.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 NADPH-dependent FMN reductase LPAM_2 PF13627.6 AIM23324.1 - 0.42 10.5 4.7 0.74 9.7 4.7 1.4 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site RcsF PF16358.5 AIM23325.1 - 1.1e-53 180.0 1.3 1.2e-53 179.8 0.9 1.2 1 1 0 1 1 1 1 RcsF lipoprotein Pilus_CpaD PF09476.10 AIM23325.1 - 0.015 15.0 0.6 0.19 11.4 0.0 2.0 1 1 1 2 2 2 0 Pilus biogenesis CpaD protein (pilus_cpaD) DUF5006 PF16397.5 AIM23325.1 - 0.038 13.2 0.1 0.055 12.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5006) DUF3558 PF12079.8 AIM23325.1 - 5.8 6.9 10.3 2.2 8.3 7.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3558) TrmO PF01980.16 AIM23326.1 - 2.8e-43 146.9 0.0 3.9e-43 146.4 0.0 1.2 1 0 0 1 1 1 1 tRNA-methyltransferase O TrmO_C PF18389.1 AIM23326.1 - 1.2e-26 92.6 4.0 5.8e-26 90.4 1.7 2.2 2 0 0 2 2 2 1 TrmO C-terminal domain Aminopep PF10023.9 AIM23326.1 - 0.12 11.7 0.1 0.17 11.2 0.1 1.1 1 0 0 1 1 1 0 Putative aminopeptidase tRNA-synt_2b PF00587.25 AIM23327.1 - 2.5e-49 167.7 0.0 3.6e-49 167.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_edit PF04073.15 AIM23327.1 - 1.2e-26 93.2 0.1 2.1e-26 92.4 0.1 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain HGTP_anticodon PF03129.20 AIM23327.1 - 1.9e-19 69.6 0.0 3.7e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain TIR_2 PF13676.6 AIM23327.1 - 0.16 12.6 0.0 0.71 10.5 0.0 2.1 2 0 0 2 2 2 0 TIR domain NlpE_C PF17185.4 AIM23328.1 - 2.9e-36 123.6 0.1 1e-35 121.9 0.0 1.9 2 0 0 2 2 2 1 NlpE C-terminal OB domain NlpE PF04170.12 AIM23328.1 - 1.3e-25 90.1 0.0 1.2e-24 87.1 0.0 2.3 2 1 1 3 3 3 1 NlpE N-terminal domain RF-1 PF00472.20 AIM23329.1 - 1.5e-23 82.9 0.4 1.8e-23 82.7 0.4 1.1 1 0 0 1 1 1 1 RF-1 domain NblA PF04485.12 AIM23329.1 - 0.086 13.3 1.1 0.17 12.3 1.1 1.5 1 0 0 1 1 1 0 Phycobilisome degradation protein nblA YaeQ PF07152.12 AIM23330.1 - 3.9e-75 251.2 1.0 4.4e-75 251.0 1.0 1.0 1 0 0 1 1 1 1 YaeQ protein UPF0253 PF06786.12 AIM23331.1 - 4.5e-37 126.2 0.9 4.9e-37 126.0 0.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0253) ROF PF07073.12 AIM23332.1 - 3e-28 97.8 0.3 3.5e-28 97.6 0.3 1.0 1 0 0 1 1 1 1 Modulator of Rho-dependent transcription termination (ROF) Cytochrom_C PF00034.21 AIM23333.1 - 4.7e-09 37.3 3.1 1.1e-08 36.1 3.1 1.5 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 AIM23333.1 - 4.8e-09 36.4 1.7 7e-09 35.9 1.7 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III DUF2059 PF09832.9 AIM23333.1 - 0.42 10.7 0.1 0.42 10.7 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2059) ATP_bind_3 PF01171.20 AIM23334.1 - 1.9e-56 190.7 0.0 2.8e-56 190.2 0.0 1.2 1 0 0 1 1 1 1 PP-loop family TilS_C PF11734.8 AIM23334.1 - 2.9e-27 93.9 1.1 7.4e-27 92.6 1.1 1.8 1 0 0 1 1 1 1 TilS substrate C-terminal domain TilS PF09179.11 AIM23334.1 - 3.7e-19 69.0 4.6 3.7e-19 69.0 4.6 3.2 3 0 0 3 3 3 1 TilS substrate binding domain Asn_synthase PF00733.21 AIM23334.1 - 4.2e-05 23.4 0.1 8.4e-05 22.4 0.1 1.5 1 0 0 1 1 1 1 Asparagine synthase PAPS_reduct PF01507.19 AIM23334.1 - 0.00023 21.3 0.0 0.00047 20.3 0.0 1.6 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family tRNA_Me_trans PF03054.16 AIM23334.1 - 0.11 11.2 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 tRNA methyl transferase PTR2 PF00854.21 AIM23335.1 - 6.1e-75 252.5 8.0 8.8e-75 252.0 8.0 1.2 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 AIM23335.1 - 9.2e-15 54.4 68.8 6.4e-14 51.6 58.9 2.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1129 PF06570.11 AIM23335.1 - 0.013 15.0 0.4 0.049 13.1 0.4 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) WD40 PF00400.32 AIM23335.1 - 0.018 15.9 0.3 0.06 14.2 0.3 1.9 1 0 0 1 1 1 0 WD domain, G-beta repeat DUF4271 PF14093.6 AIM23335.1 - 0.11 12.4 0.1 0.11 12.4 0.1 3.0 4 1 0 4 4 4 0 Domain of unknown function (DUF4271) OKR_DC_1 PF01276.20 AIM23336.1 - 7.8e-197 654.1 0.3 1.5e-196 653.1 0.1 1.5 2 0 0 2 2 2 1 Orn/Lys/Arg decarboxylase, major domain OKR_DC_1_C PF03711.15 AIM23336.1 - 3.3e-46 156.9 1.7 7.3e-46 155.7 1.3 1.9 2 0 0 2 2 2 1 Orn/Lys/Arg decarboxylase, C-terminal domain OKR_DC_1_N PF03709.15 AIM23336.1 - 1.9e-27 95.8 0.1 3.7e-27 94.8 0.1 1.5 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, N-terminal domain AA_permease_2 PF13520.6 AIM23337.1 - 5.9e-39 134.1 50.8 8.5e-39 133.6 50.8 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 AIM23337.1 - 3.3e-20 72.1 46.1 2.2e-19 69.4 46.1 1.7 1 1 0 1 1 1 1 Amino acid permease Tmemb_18A PF09771.9 AIM23337.1 - 0.045 14.1 0.3 0.12 12.7 0.3 1.7 1 0 0 1 1 1 0 Transmembrane protein 188 CadC_C1 PF18500.1 AIM23338.1 - 8.2e-72 239.6 0.1 1.4e-71 238.9 0.1 1.4 1 0 0 1 1 1 1 CadC C-terminal domain 1 Trans_reg_C PF00486.28 AIM23338.1 - 2.9e-17 62.5 0.0 4.9e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal TPR_2 PF07719.17 AIM23338.1 - 0.017 15.2 0.0 11 6.5 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyoxalase PF00903.25 AIM23339.1 - 2.5e-21 76.2 0.0 2.7e-21 76.1 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 AIM23339.1 - 3.8e-13 49.7 0.0 4.7e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 AIM23339.1 - 9.6e-08 32.3 0.0 1.1e-07 32.1 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 AIM23339.1 - 2.1e-05 25.3 0.0 2.6e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 AIM23339.1 - 0.0016 18.4 0.0 0.0031 17.4 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase-like domain OKR_DC_1 PF01276.20 AIM23340.1 - 3.2e-187 622.4 0.0 4.1e-187 622.1 0.0 1.1 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain OKR_DC_1_C PF03711.15 AIM23340.1 - 1.3e-44 151.6 0.0 2.4e-44 150.8 0.0 1.4 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, C-terminal domain OKR_DC_1_N PF03709.15 AIM23340.1 - 1.6e-28 99.2 0.0 3.3e-28 98.2 0.0 1.6 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, N-terminal domain ACCA PF03255.14 AIM23341.1 - 7.3e-47 158.9 0.8 1.2e-46 158.2 0.8 1.4 1 0 0 1 1 1 1 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Carboxyl_trans PF01039.22 AIM23341.1 - 6.5e-18 64.6 0.1 7.4e-18 64.4 0.1 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 AIM23341.1 - 0.00026 20.6 0.0 0.0003 20.4 0.0 1.1 1 0 0 1 1 1 1 Malonate decarboxylase gamma subunit (MdcE) DNA_pol3_alpha PF07733.12 AIM23342.1 - 9e-105 349.9 0.0 1.4e-104 349.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha NTPase domain DNA_pol3_finger PF17657.1 AIM23342.1 - 5e-65 217.9 0.0 8.9e-65 217.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha subunit finger domain PHP PF02811.19 AIM23342.1 - 4.8e-42 144.1 0.0 1.4e-41 142.6 0.0 1.8 2 0 0 2 2 2 1 PHP domain HHH_6 PF14579.6 AIM23342.1 - 4e-23 81.5 0.0 1e-22 80.2 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif tRNA_anti-codon PF01336.25 AIM23342.1 - 9.4e-08 31.9 0.1 2.1e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RNase_HII PF01351.18 AIM23343.1 - 1.1e-39 136.3 0.0 1.3e-39 136.1 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease HII AcetDehyd-dimer PF09290.11 AIM23343.1 - 0.11 12.7 0.0 0.23 11.6 0.0 1.5 1 1 0 1 1 1 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation LpxB PF02684.15 AIM23344.1 - 5.9e-143 476.2 0.0 6.7e-143 476.1 0.0 1.0 1 0 0 1 1 1 1 Lipid-A-disaccharide synthetase Acetyltransf_11 PF13720.6 AIM23345.1 - 3.9e-30 104.1 0.0 6.1e-30 103.5 0.0 1.3 1 0 0 1 1 1 1 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Hexapep PF00132.24 AIM23345.1 - 8.1e-23 79.2 28.4 3.5e-08 32.8 4.6 6.3 3 3 3 6 6 6 6 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AIM23345.1 - 0.04 13.7 2.3 0.04 13.7 2.3 4.8 2 2 1 4 4 4 0 Hexapeptide repeat of succinyl-transferase Serine_rich PF08824.10 AIM23345.1 - 0.086 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Serine rich protein interaction domain FabA PF07977.13 AIM23346.1 - 5.6e-41 139.4 0.0 6.4e-41 139.2 0.0 1.0 1 0 0 1 1 1 1 FabA-like domain MaoC_dehydratas PF01575.19 AIM23346.1 - 0.0067 16.0 0.0 0.0088 15.6 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain 4HBT PF03061.22 AIM23346.1 - 0.017 15.5 0.0 0.034 14.5 0.0 1.6 1 1 0 1 1 1 0 Thioesterase superfamily PS-DH PF14765.6 AIM23346.1 - 0.026 13.8 0.0 0.04 13.2 0.0 1.3 1 1 0 1 1 1 0 Polyketide synthase dehydratase Hexapep PF00132.24 AIM23347.1 - 3.5e-30 102.6 33.4 1.5e-09 37.2 1.5 5.6 4 1 2 6 6 6 6 Bacterial transferase hexapeptide (six repeats) LpxD PF04613.14 AIM23347.1 - 3.4e-25 87.6 0.1 6.5e-25 86.7 0.1 1.5 1 0 0 1 1 1 1 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD Hexapep_2 PF14602.6 AIM23347.1 - 2e-12 46.6 33.5 3.2e-07 30.0 3.6 5.4 4 1 1 5 5 5 4 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 AIM23347.1 - 0.013 13.7 4.0 0.83 7.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4954) OmpH PF03938.14 AIM23348.1 - 9.7e-33 113.4 14.8 1.1e-32 113.2 14.8 1.0 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) YnfE PF17452.2 AIM23348.1 - 0.00069 19.9 7.6 0.049 13.9 0.9 2.6 1 1 1 2 2 2 2 Uncharacterized YnfE-like Macoilin PF09726.9 AIM23348.1 - 0.0087 14.7 10.8 0.0099 14.5 10.8 1.0 1 0 0 1 1 1 1 Macoilin family ECM11 PF15463.6 AIM23348.1 - 0.015 15.9 0.3 0.015 15.9 0.3 2.1 2 0 0 2 2 2 0 Extracellular mutant protein 11 PIN_8 PF18476.1 AIM23348.1 - 0.021 14.7 4.8 0.027 14.3 4.8 1.2 1 0 0 1 1 1 0 PIN like domain Exonuc_VII_L PF02601.15 AIM23348.1 - 0.05 13.2 5.1 0.057 13.0 5.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3552 PF12072.8 AIM23348.1 - 0.063 12.7 14.1 0.13 11.6 14.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) DUF2203 PF09969.9 AIM23348.1 - 0.47 11.2 8.5 2.4 8.9 0.9 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) XkdW PF09636.10 AIM23348.1 - 0.53 10.4 3.4 16 5.6 0.6 2.2 1 1 1 2 2 2 0 XkdW protein DUF16 PF01519.16 AIM23348.1 - 1.8 9.1 8.9 5.9 7.4 8.8 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF16 LMBR1 PF04791.16 AIM23348.1 - 2.2 7.1 3.8 2.6 6.9 3.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein HIP1_clath_bdg PF16515.5 AIM23348.1 - 2.4 8.8 15.2 2 9.1 4.1 2.2 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TMPIT PF07851.13 AIM23348.1 - 5.9 6.0 6.9 9.4 5.4 7.1 1.3 1 1 0 1 1 1 0 TMPIT-like protein Bac_surface_Ag PF01103.23 AIM23349.1 - 5.2e-99 331.8 17.7 5.2e-99 331.8 17.7 1.6 2 0 0 2 2 2 1 Surface antigen POTRA PF07244.15 AIM23349.1 - 2.5e-61 204.2 12.5 4.4e-15 56.0 0.1 5.4 5 0 0 5 5 5 5 Surface antigen variable number repeat POTRA_1 PF08478.10 AIM23349.1 - 1.1e-07 32.1 1.3 0.18 12.1 0.0 4.9 5 0 0 5 5 5 2 POTRA domain, FtsQ-type POTRA_2 PF08479.11 AIM23349.1 - 1.2e-05 25.0 1.2 3.8 7.4 0.0 5.6 6 0 0 6 6 6 2 POTRA domain, ShlB-type PG_binding_1 PF01471.18 AIM23349.1 - 0.074 13.3 0.1 0.71 10.1 0.1 2.7 2 0 0 2 2 2 0 Putative peptidoglycan binding domain Peptidase_M50 PF02163.22 AIM23350.1 - 3e-87 292.0 0.1 3.6e-87 291.8 0.1 1.0 1 0 0 1 1 1 1 Peptidase family M50 PDZ_6 PF17820.1 AIM23350.1 - 4.7e-12 45.6 3.2 2e-10 40.4 0.3 2.8 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 AIM23350.1 - 5.2e-11 42.7 0.0 1.3e-09 38.3 0.0 2.3 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 AIM23350.1 - 1.3e-10 41.5 0.1 3.1e-08 33.8 0.0 2.3 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 AIM23350.1 - 0.0032 17.4 0.1 0.14 12.1 0.0 2.6 2 0 0 2 2 2 1 Tricorn protease PDZ domain Peptidase_M50B PF13398.6 AIM23350.1 - 0.18 11.4 0.2 0.18 11.4 0.2 2.7 3 0 0 3 3 3 0 Peptidase M50B-like CTP_transf_1 PF01148.20 AIM23351.1 - 5.7e-73 245.9 15.2 6.6e-73 245.7 15.2 1.0 1 0 0 1 1 1 1 Cytidylyltransferase family DUF4131 PF13567.6 AIM23351.1 - 0.17 11.5 30.2 0.23 11.1 7.0 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) DUF92 PF01940.16 AIM23351.1 - 0.21 11.0 0.1 0.21 11.0 0.1 2.4 2 1 0 2 2 2 0 Integral membrane protein DUF92 DUF3792 PF12670.7 AIM23351.1 - 0.96 9.6 22.8 8.3 6.6 9.4 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3792) DUF2070 PF09843.9 AIM23351.1 - 3.6 5.8 19.5 1.6e+02 0.4 19.6 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) Prenyltransf PF01255.19 AIM23352.1 - 1e-76 257.4 0.0 1.2e-76 257.2 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DXP_reductoisom PF02670.16 AIM23353.1 - 1.2e-44 152.2 4.2 1.2e-44 152.2 4.2 1.9 2 0 0 2 2 2 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXPR_C PF13288.6 AIM23353.1 - 2.3e-42 143.9 0.4 4.7e-42 142.9 0.4 1.5 1 0 0 1 1 1 1 DXP reductoisomerase C-terminal domain DXP_redisom_C PF08436.12 AIM23353.1 - 9.8e-37 125.0 0.0 2e-36 124.0 0.0 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain RRF PF01765.19 AIM23354.1 - 1.3e-63 213.8 2.3 1.3e-63 213.8 2.3 1.4 1 1 0 1 1 1 1 Ribosome recycling factor TPP1 PF10341.9 AIM23354.1 - 0.0009 19.2 0.1 0.0013 18.7 0.1 1.5 1 1 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD AA_kinase PF00696.28 AIM23355.1 - 1.8e-27 96.5 0.2 2.2e-27 96.2 0.2 1.1 1 0 0 1 1 1 1 Amino acid kinase family EF_TS PF00889.19 AIM23356.1 - 2.8e-67 226.3 3.8 2.8e-67 226.3 3.8 1.5 2 0 0 2 2 2 1 Elongation factor TS CUE PF02845.16 AIM23356.1 - 0.036 13.8 0.0 0.38 10.5 0.0 2.3 2 0 0 2 2 2 0 CUE domain HOIP-UBA PF16678.5 AIM23356.1 - 0.071 13.1 0.4 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 HOIP UBA domain pair Ribosomal_S2 PF00318.20 AIM23357.1 - 1.3e-92 308.9 0.0 1.4e-92 308.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S2 Peptidase_M24 PF00557.24 AIM23358.1 - 2.5e-52 177.6 0.3 2.9e-52 177.4 0.3 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 GlnD_UR_UTase PF08335.11 AIM23359.1 - 6.2e-36 123.7 0.6 6.2e-36 123.7 0.6 2.7 3 0 0 3 3 3 1 GlnD PII-uridylyltransferase ACT PF01842.25 AIM23359.1 - 1.3e-17 63.2 0.0 1.6e-08 34.2 0.0 2.6 2 0 0 2 2 2 2 ACT domain HD PF01966.22 AIM23359.1 - 2.2e-15 57.0 0.0 5.9e-15 55.6 0.0 1.8 1 0 0 1 1 1 1 HD domain NTP_transf_2 PF01909.23 AIM23359.1 - 9e-07 29.1 0.0 2.6e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF294 PF03445.13 AIM23359.1 - 2.8e-05 24.0 0.0 0.00011 22.1 0.0 2.0 1 0 0 1 1 1 1 Putative nucleotidyltransferase DUF294 Polbeta PF18765.1 AIM23359.1 - 0.09 12.9 0.0 0.32 11.1 0.0 1.9 2 0 0 2 2 2 0 Polymerase beta, Nucleotidyltransferase THDPS_N_2 PF14805.6 AIM23360.1 - 4.3e-25 87.7 0.4 6.8e-25 87.1 0.4 1.3 1 0 0 1 1 1 1 Tetrahydrodipicolinate N-succinyltransferase N-terminal Hexapep_2 PF14602.6 AIM23360.1 - 5.3e-13 48.5 6.7 7.8e-13 47.9 0.7 2.6 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 AIM23360.1 - 1.7e-12 46.5 7.2 1.9e-06 27.4 0.3 3.5 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Cas3_C PF18395.1 AIM23360.1 - 0.18 12.3 0.0 0.55 10.8 0.0 1.8 2 0 0 2 2 2 0 Cas3 C-terminal domain DUF3461 PF11944.8 AIM23361.1 - 2.2e-54 182.9 2.2 2.5e-54 182.7 2.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3461) Flavodoxin_1 PF00258.25 AIM23362.1 - 5e-23 81.9 0.0 5.9e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin PseudoU_synth_2 PF00849.22 AIM23363.1 - 3.5e-36 124.7 0.3 4.6e-36 124.3 0.3 1.1 1 0 0 1 1 1 1 RNA pseudouridylate synthase Transgly PF00912.22 AIM23364.1 - 7.2e-41 139.6 0.0 1.8e-40 138.3 0.0 1.6 1 0 0 1 1 1 1 Transglycosylase Transpeptidase PF00905.22 AIM23364.1 - 1e-17 64.4 0.0 1.8e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain BiPBP_C PF06832.12 AIM23364.1 - 1.8e-16 60.0 0.1 8.9e-16 57.7 0.0 2.2 2 0 0 2 2 2 1 Penicillin-Binding Protein C-terminus Family bMG3 PF11974.8 AIM23365.1 - 5.3e-25 87.4 2.9 2.6e-24 85.2 0.3 3.3 3 0 0 3 3 3 1 Bacterial alpha-2-macroglobulin MG3 domain bMG10 PF17973.1 AIM23365.1 - 4.5e-20 72.2 0.1 6e-19 68.5 0.0 2.8 2 0 0 2 2 2 1 Bacterial Alpha-2-macroglobulin MG10 domain A2M_BRD PF07703.14 AIM23365.1 - 9.5e-18 64.9 0.2 2.8e-15 56.9 0.0 3.5 4 0 0 4 4 4 1 Alpha-2-macroglobulin bait region domain MG2 PF01835.19 AIM23365.1 - 4.3e-17 62.3 0.0 2.7e-16 59.8 0.0 2.5 1 0 0 1 1 1 1 MG2 domain bMG5 PF17972.1 AIM23365.1 - 5.8e-14 52.5 0.7 3.6e-12 46.8 0.1 3.5 4 0 0 4 4 4 1 Bacterial Alpha-2-macroglobulin MG5 domain A2M PF00207.22 AIM23365.1 - 2.7e-11 43.2 0.1 1.1e-10 41.2 0.0 2.1 2 0 0 2 2 2 1 Alpha-2-macroglobulin family Big_5 PF13205.6 AIM23365.1 - 4.8e-06 27.2 1.2 0.24 12.1 0.0 3.5 4 0 0 4 4 3 2 Bacterial Ig-like domain bMG6 PF17962.1 AIM23365.1 - 7.2e-06 26.1 0.1 3.3e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 Bacterial macroglobulin domain 6 CarboxypepD_reg PF13620.6 AIM23365.1 - 0.00089 19.5 0.3 0.0059 16.8 0.3 2.5 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain Big_10 PF17964.1 AIM23365.1 - 0.0016 18.4 0.0 0.0061 16.6 0.0 1.9 1 0 0 1 1 1 1 Bacterial Ig domain DUF11 PF01345.18 AIM23365.1 - 0.022 15.0 3.8 1.9 8.8 0.0 4.2 3 0 0 3 3 3 0 Domain of unknown function DUF11 DUF2914 PF11141.8 AIM23365.1 - 0.047 13.4 0.0 3.3 7.5 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2914) Big_1 PF02369.16 AIM23365.1 - 0.1 12.6 5.6 0.089 12.8 0.8 3.5 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 1) DUF446 PF04287.12 AIM23366.1 - 1.4e-35 121.2 1.9 1.6e-35 121.0 1.9 1.0 1 0 0 1 1 1 1 tRNA pseudouridine synthase C RuBisCo_chap_C PF18087.1 AIM23366.1 - 0.021 14.5 0.0 0.023 14.4 0.0 1.1 1 0 0 1 1 1 0 Rubisco Assembly chaperone C-terminal domain MFS_1 PF07690.16 AIM23367.1 - 1.6e-54 185.2 64.6 1.2e-43 149.4 34.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AIM23367.1 - 2.7e-20 72.7 36.4 1.1e-18 67.4 11.5 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 AIM23367.1 - 4.2e-06 26.3 28.7 6.6e-06 25.7 28.7 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 AIM23367.1 - 0.00084 17.8 3.6 0.00084 17.8 3.6 2.6 2 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 AIM23367.1 - 0.025 13.5 29.9 0.03 13.2 7.8 2.4 1 1 1 2 2 2 0 MFS_1 like family Syd PF07348.12 AIM23368.1 - 2.9e-70 235.5 0.0 3.2e-70 235.3 0.0 1.0 1 0 0 1 1 1 1 Syd protein (SUKH-2) QueF_N PF14819.6 AIM23369.1 - 8.7e-48 161.2 0.0 2.2e-47 159.9 0.0 1.6 2 0 0 2 2 2 1 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term QueF PF14489.6 AIM23369.1 - 2e-32 111.2 0.0 9.6e-27 93.0 0.0 2.3 2 0 0 2 2 2 2 QueF-like protein DUF3412 PF11892.8 AIM23370.1 - 4.2e-57 191.5 0.0 8.8e-57 190.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3412) DUF4478 PF14793.6 AIM23370.1 - 2.5e-47 159.2 0.1 5.2e-47 158.2 0.1 1.5 1 0 0 1 1 1 1 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidases Lysine_decarbox PF03641.14 AIM23370.1 - 6.6e-34 116.8 0.0 1e-33 116.3 0.0 1.3 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 AIM23370.1 - 1.2e-05 25.0 0.0 2.1e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 SLOG cluster4 family 5_3_exonuc_N PF02739.16 AIM23371.1 - 4.3e-32 111.2 0.0 5.7e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 AIM23371.1 - 1.1e-24 86.8 0.0 1.8e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold RlmM_FDX PF18125.1 AIM23372.1 - 4.5e-32 110.4 0.2 9.3e-32 109.3 0.2 1.6 1 0 0 1 1 1 1 RlmM ferredoxin-like domain FtsJ PF01728.19 AIM23372.1 - 2e-08 34.5 0.0 4.3e-08 33.5 0.0 1.5 2 0 0 2 2 2 1 FtsJ-like methyltransferase Spt5-NGN PF03439.13 AIM23372.1 - 0.00016 21.5 0.0 0.00033 20.5 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section DUF4222 PF13973.6 AIM23372.1 - 0.015 14.9 0.1 5.8 6.6 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4222) DUF423 PF04241.15 AIM23373.1 - 2.4e-24 85.3 5.9 2.4e-24 85.3 5.9 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF423) Phage_holin_3_6 PF07332.11 AIM23373.1 - 0.00058 19.9 6.6 0.00058 19.9 6.6 2.1 1 1 1 2 2 2 1 Putative Actinobacterial Holin-X, holin superfamily III LapA_dom PF06305.11 AIM23373.1 - 0.062 13.1 1.2 0.062 13.1 1.2 2.9 2 1 1 3 3 3 0 Lipopolysaccharide assembly protein A domain COA2 PF17051.5 AIM23373.1 - 0.14 12.3 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase assembly factor 2 YrhK PF14145.6 AIM23373.1 - 0.21 11.5 6.9 0.85 9.5 6.9 2.0 1 1 0 1 1 1 0 YrhK-like protein SLC3A2_N PF16028.5 AIM23373.1 - 1 9.0 9.7 0.28 10.7 2.9 2.5 1 1 1 2 2 2 0 Solute carrier family 3 member 2 N-terminus DUF4233 PF14017.6 AIM23373.1 - 5.4 7.4 17.4 2.2 8.7 12.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4233) LysR_substrate PF03466.20 AIM23374.1 - 2.9e-40 137.9 1.0 4.5e-40 137.3 1.0 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM23374.1 - 9.8e-22 76.7 1.8 1.8e-21 75.8 1.8 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AIM23374.1 - 0.048 13.5 0.3 0.11 12.4 0.3 1.5 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain DUF903 PF06004.12 AIM23375.1 - 2.7e-26 91.2 2.3 3.2e-26 90.9 2.3 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF903) LPAM_1 PF08139.12 AIM23375.1 - 0.054 14.0 4.8 0.079 13.5 4.8 1.3 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Aminotran_5 PF00266.19 AIM23376.1 - 2.5e-138 461.1 0.0 2.9e-138 460.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 AIM23376.1 - 0.022 13.3 0.0 0.031 12.8 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme ART PF01129.18 AIM23376.1 - 0.096 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 NAD:arginine ADP-ribosyltransferase SufE PF02657.15 AIM23377.1 - 7.7e-39 132.3 0.0 8.8e-39 132.1 0.0 1.0 1 0 0 1 1 1 1 Fe-S metabolism associated domain ThiF PF00899.21 AIM23378.1 - 4.9e-37 127.6 1.0 7.3e-37 127.0 1.0 1.2 1 1 0 1 1 1 1 ThiF family DAO PF01266.24 AIM23378.1 - 0.0003 20.5 0.7 0.00054 19.7 0.7 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 AIM23378.1 - 0.0017 17.9 1.2 0.0038 16.8 1.2 1.7 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 AIM23378.1 - 0.0027 18.0 1.0 0.016 15.4 1.0 2.1 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ELFV_dehydrog PF00208.21 AIM23378.1 - 0.0044 16.8 0.0 0.0069 16.1 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 3HCDH_N PF02737.18 AIM23378.1 - 0.009 15.9 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 AIM23378.1 - 0.013 15.9 0.1 0.038 14.4 0.1 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 AIM23378.1 - 0.032 13.5 0.0 0.044 13.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AIM23378.1 - 0.096 11.9 0.2 0.13 11.5 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.18 AIM23378.1 - 0.1 12.8 0.5 0.66 10.2 0.2 2.1 1 1 1 2 2 2 0 TrkA-N domain Shikimate_DH PF01488.20 AIM23378.1 - 0.14 12.2 1.0 0.27 11.3 0.3 1.8 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase MltA PF03562.17 AIM23379.1 - 7.1e-39 133.9 9.5 7.8e-38 130.5 5.7 2.8 2 1 0 2 2 2 1 MltA specific insert domain 3D PF06725.11 AIM23379.1 - 8.4e-25 86.8 0.1 1.9e-24 85.6 0.1 1.6 1 0 0 1 1 1 1 3D domain Amidase_3 PF01520.18 AIM23380.1 - 2.3e-50 171.1 0.2 3.6e-50 170.5 0.2 1.3 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase AMIN PF11741.8 AIM23380.1 - 3.1e-25 88.1 0.1 5.9e-25 87.2 0.1 1.5 1 0 0 1 1 1 1 AMIN domain Herpes_pp85 PF04637.12 AIM23380.1 - 0.045 12.2 0.0 0.061 11.7 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) AA_kinase PF00696.28 AIM23381.1 - 4.1e-30 105.2 0.2 5.5e-30 104.7 0.2 1.2 1 0 0 1 1 1 1 Amino acid kinase family Acetyltransf_1 PF00583.25 AIM23381.1 - 1e-09 38.6 0.0 6e-08 32.9 0.0 2.5 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AIM23381.1 - 4.6e-07 30.2 0.0 1.6e-05 25.2 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AIM23381.1 - 2.7e-05 24.1 0.0 0.00071 19.5 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AIM23381.1 - 0.055 13.6 0.0 0.16 12.1 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain AAA_30 PF13604.6 AIM23382.1 - 7.9e-34 117.1 5.0 3.4e-32 111.7 4.3 2.4 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.6 AIM23382.1 - 5.3e-30 104.7 0.3 1e-29 103.8 0.3 1.5 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 AIM23382.1 - 2.5e-16 60.0 0.1 4.2e-16 59.3 0.1 1.3 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 AIM23382.1 - 8.5e-16 57.5 0.2 1.7e-15 56.6 0.2 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 AIM23382.1 - 5.8e-13 49.1 2.0 1.2e-06 28.5 0.1 3.2 2 1 1 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 AIM23382.1 - 3.2e-10 40.2 0.1 6.6e-06 26.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 AIM23382.1 - 1.4e-06 28.7 0.0 2.9e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain SH3_13 PF18335.1 AIM23382.1 - 3.8e-06 26.6 0.0 6.6e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent RecD-like DNA helicase SH3 domain UvrD-helicase PF00580.21 AIM23382.1 - 3.9e-06 26.6 0.1 6.1e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain PhoH PF02562.16 AIM23382.1 - 4.6e-06 26.2 0.0 8.3e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein DUF2075 PF09848.9 AIM23382.1 - 6.1e-06 25.7 0.0 2.5e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.6 AIM23382.1 - 0.001 19.3 0.7 0.004 17.4 0.1 2.2 2 0 0 2 2 2 1 AAA domain UvrD_C PF13361.6 AIM23382.1 - 0.0023 17.4 0.0 0.0039 16.6 0.0 1.2 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain T2SSE PF00437.20 AIM23382.1 - 0.0027 16.8 0.0 0.0055 15.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein CbiA PF01656.23 AIM23382.1 - 0.0051 16.9 0.2 0.011 15.8 0.2 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 AIM23382.1 - 0.008 16.6 2.4 0.008 16.6 2.4 2.5 3 2 0 3 3 2 1 AAA ATPase domain AAA PF00004.29 AIM23382.1 - 0.045 14.2 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 AIM23382.1 - 0.053 13.1 0.1 0.089 12.4 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 AIM23382.1 - 0.1 12.5 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 NTPase TrwB_AAD_bind PF10412.9 AIM23382.1 - 0.12 11.2 0.1 0.21 10.5 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain MukB PF04310.12 AIM23382.1 - 0.14 12.0 0.2 0.27 11.0 0.2 1.4 1 0 0 1 1 1 0 MukB N-terminal AAA_24 PF13479.6 AIM23382.1 - 0.18 11.5 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 AIM23382.1 - 0.21 11.7 0.1 0.37 10.9 0.1 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain UvrD-helicase PF00580.21 AIM23383.1 - 3.9e-61 207.3 0.0 8.3e-61 206.2 0.0 1.6 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 AIM23383.1 - 1.8e-22 80.2 0.0 4e-12 46.2 0.0 3.0 1 1 1 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 AIM23383.1 - 1.9e-18 67.2 0.0 8.9e-18 65.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 AIM23383.1 - 3.5e-07 29.9 0.3 0.005 16.6 0.0 2.9 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain PDDEXK_1 PF12705.7 AIM23383.1 - 8.4e-05 22.6 0.0 0.00037 20.5 0.0 2.1 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily AAA_30 PF13604.6 AIM23383.1 - 0.0025 17.5 0.1 0.48 10.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 AIM23383.1 - 0.068 12.9 0.0 0.27 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 AIM23383.1 - 0.068 13.4 1.1 6.4 7.0 0.0 3.8 4 0 0 4 4 4 0 AAA domain AAA_12 PF13087.6 AIM23383.1 - 0.1 12.2 0.0 0.29 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Peptidase_M16_M PF16187.5 AIM23384.1 - 5.1e-57 193.3 3.0 6.4e-57 193.0 0.1 2.1 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 AIM23384.1 - 6.4e-35 120.3 0.0 1.7e-34 118.9 0.0 1.8 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 AIM23384.1 - 1.6e-32 113.0 0.1 8.7e-20 71.5 0.0 3.7 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M3_N PF08439.10 AIM23384.1 - 0.07 13.4 0.2 0.21 11.9 0.2 1.8 1 0 0 1 1 1 0 Oligopeptidase F RPAP1_N PF08621.10 AIM23384.1 - 2.4 8.0 6.1 1.4 8.8 1.4 3.0 4 0 0 4 4 4 0 RPAP1-like, N-terminal T2SSppdC PF12528.8 AIM23385.1 - 1e-23 83.9 6.6 1.3e-23 83.6 6.6 1.1 1 0 0 1 1 1 1 Type II secretion prepilin peptidase dependent protein C N_methyl PF07963.12 AIM23385.1 - 4.8e-05 22.7 0.2 6.8e-05 22.3 0.2 1.2 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif MBD PF01429.19 AIM23385.1 - 0.094 12.4 1.0 0.24 11.1 0.1 2.0 2 0 0 2 2 2 0 Methyl-CpG binding domain DUF2509 PF10713.9 AIM23386.1 - 2.9e-36 124.4 1.3 3.4e-36 124.2 1.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2509) N_methyl PF07963.12 AIM23387.1 - 0.00064 19.2 1.0 0.0014 18.1 1.0 1.6 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif N_methyl PF07963.12 AIM23388.1 - 1e-06 28.0 0.0 1.7e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif HemX PF04375.14 AIM23388.1 - 0.12 11.7 0.6 0.15 11.3 0.6 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Thymidylat_synt PF00303.19 AIM23389.1 - 6.3e-127 422.2 0.0 7e-127 422.1 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase DASH_Hsk3 PF08227.11 AIM23389.1 - 0.056 13.8 0.7 13 6.3 0.0 2.5 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like LGT PF01790.18 AIM23390.1 - 1.3e-79 266.8 7.8 1.5e-79 266.6 7.8 1.0 1 0 0 1 1 1 1 Prolipoprotein diacylglyceryl transferase DUF4328 PF14219.6 AIM23390.1 - 0.013 15.1 3.9 2.7 7.5 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4328) DUF202 PF02656.15 AIM23390.1 - 0.49 10.9 8.3 5.1 7.6 0.2 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF202) PEP-utilizers_C PF02896.18 AIM23391.1 - 3.4e-102 341.5 0.0 4.6e-102 341.1 0.0 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilisers_N PF05524.13 AIM23391.1 - 3.8e-24 85.1 2.4 9.1e-24 83.9 2.4 1.7 1 0 0 1 1 1 1 PEP-utilising enzyme, N-terminal GAF PF01590.26 AIM23391.1 - 2.2e-15 57.4 0.1 7e-15 55.8 0.1 1.9 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 AIM23391.1 - 6.9e-15 55.6 0.0 1.8e-14 54.2 0.0 1.8 1 0 0 1 1 1 1 GAF domain PEP-utilizers PF00391.23 AIM23391.1 - 8.1e-15 54.3 0.3 2e-14 53.0 0.1 1.8 2 0 0 2 2 2 1 PEP-utilising enzyme, mobile domain GAF_3 PF13492.6 AIM23391.1 - 2e-11 44.3 0.1 7.7e-11 42.4 0.1 2.1 1 1 0 1 1 1 1 GAF domain Lipase_GDSL PF00657.22 AIM23391.1 - 0.23 11.4 0.0 1.3 8.9 0.0 2.1 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase NUDIX PF00293.28 AIM23392.1 - 1.7e-28 99.3 0.1 2.3e-28 98.9 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain MutH PF02976.15 AIM23393.1 - 9.2e-33 112.3 0.0 1.2e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 DNA mismatch repair enzyme MutH Tugs PF17840.1 AIM23393.1 - 0.11 12.7 0.2 2.9 8.2 0.1 2.4 2 0 0 2 2 2 0 Tethering Ubl4a to BAGS domain MvaI_BcnI PF15515.6 AIM23393.1 - 0.15 11.9 0.0 0.29 10.9 0.0 1.4 2 0 0 2 2 2 0 MvaI/BcnI restriction endonuclease family TerC PF03741.16 AIM23394.1 - 2.5e-53 180.5 15.7 3.1e-53 180.1 15.7 1.1 1 0 0 1 1 1 1 Integral membrane protein TerC family LysE PF01810.18 AIM23394.1 - 0.0033 16.9 9.2 0.021 14.3 4.6 2.4 2 0 0 2 2 2 2 LysE type translocator DUF4131 PF13567.6 AIM23394.1 - 1.6 8.3 10.1 5.1 6.7 0.6 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Tetraspanin PF00335.20 AIM23394.1 - 7.6 6.2 6.2 3.6 7.2 3.3 1.9 2 0 0 2 2 2 0 Tetraspanin family DUF903 PF06004.12 AIM23395.1 - 1.1e-23 82.9 3.3 1.2e-23 82.7 3.3 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF903) LPAM_1 PF08139.12 AIM23395.1 - 0.047 14.2 2.0 0.08 13.5 2.0 1.4 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site MLTD_N PF06474.12 AIM23395.1 - 0.8 9.9 3.8 1.3 9.3 3.8 1.3 1 0 0 1 1 1 0 MltD lipid attachment motif Aldo_ket_red PF00248.21 AIM23396.1 - 3.8e-73 246.2 0.0 4.3e-73 246.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Octopine_DH PF02317.17 AIM23396.1 - 0.13 12.3 0.0 1.9 8.6 0.0 2.1 2 0 0 2 2 2 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain MFS_1 PF07690.16 AIM23397.1 - 5.3e-17 61.8 43.2 5.3e-17 61.8 43.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1427 PF07235.11 AIM23397.1 - 1.7 8.7 7.6 0.074 13.0 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1427) AMP-binding PF00501.28 AIM23398.1 - 2.8e-66 223.9 0.0 3.8e-66 223.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Acyltransferase PF01553.21 AIM23398.1 - 7.1e-15 54.8 0.0 1.3e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase AMP-binding_C PF13193.6 AIM23398.1 - 0.0037 18.2 0.0 0.01 16.8 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Molybdopterin PF00384.22 AIM23399.1 - 4.2e-59 200.6 0.0 5.1e-59 200.4 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 AIM23399.1 - 6.4e-27 93.8 0.0 4.6e-26 91.0 0.0 2.3 2 0 0 2 2 2 1 Molydopterin dinucleotide binding domain Molybdopterin_N PF18364.1 AIM23399.1 - 1.1e-17 63.7 0.1 1.1e-16 60.6 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin oxidoreductase N-terminal domain Peripla_BP_3 PF13377.6 AIM23400.1 - 3.7e-33 115.2 3.0 1.1e-32 113.7 0.2 2.5 2 1 1 3 3 3 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 AIM23400.1 - 3.3e-28 98.9 0.0 5.4e-28 98.2 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 AIM23400.1 - 3.9e-21 74.6 1.5 9.2e-21 73.4 0.7 2.1 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 AIM23400.1 - 3.5e-13 49.7 0.0 2.5e-12 46.9 0.0 2.2 2 1 0 2 2 2 1 Periplasmic binding protein domain HTH_Tnp_ISL3 PF13542.6 AIM23400.1 - 0.0012 18.3 4.4 0.0034 16.8 0.3 3.3 4 0 0 4 4 4 1 Helix-turn-helix domain of transposase family ISL3 HTH_3 PF01381.22 AIM23400.1 - 0.012 15.6 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix HTH_31 PF13560.6 AIM23400.1 - 0.026 14.9 0.2 0.13 12.6 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.6 AIM23400.1 - 0.032 14.0 0.7 0.11 12.3 0.0 2.3 3 0 0 3 3 2 0 Homeodomain-like domain MerR PF00376.23 AIM23400.1 - 0.048 13.4 0.2 0.11 12.3 0.2 1.6 1 0 0 1 1 1 0 MerR family regulatory protein HTH_17 PF12728.7 AIM23400.1 - 0.059 13.6 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_7 PF02796.15 AIM23400.1 - 0.076 13.1 0.5 0.68 10.1 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_38 PF13936.6 AIM23400.1 - 0.098 12.4 2.3 0.44 10.4 0.1 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_26 PF13443.6 AIM23400.1 - 0.11 13.0 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain DUF3853 PF12964.7 AIM23400.1 - 0.11 12.7 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3853) HTH_29 PF13551.6 AIM23400.1 - 0.15 12.1 0.2 4.6 7.3 0.1 2.6 2 1 0 2 2 2 0 Winged helix-turn helix Gp49 PF05973.14 AIM23401.1 - 2.6e-17 62.7 0.0 3.9e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Phage derived protein Gp49-like (DUF891) HTH_37 PF13744.6 AIM23402.1 - 9.1e-12 44.8 0.3 1.2e-11 44.4 0.3 1.3 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 AIM23402.1 - 5.3e-09 36.0 0.8 7.8e-09 35.5 0.8 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 AIM23402.1 - 3.5e-06 27.3 0.2 5.9e-06 26.5 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 AIM23402.1 - 0.00018 21.4 0.2 0.00028 20.8 0.2 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain YdaS_antitoxin PF15943.5 AIM23402.1 - 0.0018 18.1 0.0 0.0037 17.1 0.0 1.6 1 1 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Sigma70_r4 PF04545.16 AIM23402.1 - 0.0031 17.0 0.1 0.0059 16.1 0.1 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_24 PF13412.6 AIM23402.1 - 0.004 16.7 0.1 0.01 15.4 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_26 PF13443.6 AIM23402.1 - 0.0073 16.7 0.1 0.011 16.2 0.1 1.4 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_25 PF13413.6 AIM23402.1 - 0.014 15.3 0.3 0.027 14.3 0.3 1.6 1 1 0 1 1 1 0 Helix-turn-helix domain MarR PF01047.22 AIM23402.1 - 0.019 14.9 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_23 PF13384.6 AIM23402.1 - 0.023 14.5 0.0 0.038 13.8 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_39 PF14090.6 AIM23402.1 - 0.026 14.3 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain MarR_2 PF12802.7 AIM23402.1 - 0.027 14.3 0.0 0.049 13.5 0.0 1.5 1 0 0 1 1 1 0 MarR family Phage_CI_repr PF07022.13 AIM23402.1 - 0.03 14.4 0.0 0.056 13.5 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain HTH_6 PF01418.17 AIM23402.1 - 0.039 13.9 0.1 0.06 13.3 0.1 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family HTH_AsnC-type PF13404.6 AIM23402.1 - 0.054 13.3 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_50 PF18024.1 AIM23402.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Orn_Arg_deC_N PF02784.16 AIM23403.1 - 1.2e-58 198.5 0.0 1.5e-58 198.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 AIM23403.1 - 4.6e-27 94.1 0.0 4.8e-27 94.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain LysR_substrate PF03466.20 AIM23404.1 - 9.9e-41 139.4 2.6 1.3e-40 139.0 2.6 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM23404.1 - 1.5e-15 56.9 1.3 1.5e-15 56.9 1.3 2.2 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_28 PF13518.6 AIM23404.1 - 0.0045 17.1 0.1 0.0098 16.0 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_30 PF13556.6 AIM23404.1 - 0.02 14.7 0.1 0.047 13.5 0.1 1.6 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_23 PF13384.6 AIM23404.1 - 0.039 13.8 0.0 0.084 12.7 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Crp_2 PF13545.6 AIM23404.1 - 0.081 12.9 0.1 0.19 11.7 0.1 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain LysR_substrate PF03466.20 AIM23405.1 - 4.9e-43 146.9 0.5 6.9e-43 146.4 0.5 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM23405.1 - 5.5e-16 58.3 0.9 1e-15 57.4 0.9 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MHB PF16525.5 AIM23405.1 - 0.026 14.8 0.0 1.2 9.5 0.0 2.9 3 0 0 3 3 3 0 Haemophore, haem-binding HTH_45 PF14947.6 AIM23405.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix Lactamase_B PF00753.27 AIM23406.1 - 1.1e-09 38.6 0.1 1.4e-09 38.2 0.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AIM23406.1 - 0.0029 17.2 0.0 0.021 14.4 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Sulfotransfer_3 PF13469.6 AIM23406.1 - 0.082 13.3 0.0 0.25 11.7 0.0 1.8 2 0 0 2 2 2 0 Sulfotransferase family DSBA PF01323.20 AIM23407.1 - 1.2e-07 31.7 0.0 2.8e-07 30.5 0.0 1.5 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_5 PF13743.6 AIM23407.1 - 0.013 15.2 0.0 0.06 13.0 0.0 1.9 1 1 0 1 1 1 0 Thioredoxin ABC_membrane_2 PF06472.15 AIM23408.1 - 2.6e-61 207.4 8.5 3.3e-61 207.1 8.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 SbmA_BacA PF05992.12 AIM23408.1 - 1.4e-38 133.1 10.1 1.8e-38 132.7 10.1 1.1 1 0 0 1 1 1 1 SbmA/BacA-like family ABC_tran PF00005.27 AIM23408.1 - 1.1e-21 77.8 0.0 2.3e-21 76.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 AIM23408.1 - 4.7e-06 27.1 0.0 9.8e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 AIM23408.1 - 0.00011 22.1 0.1 0.0024 17.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AIM23408.1 - 0.00014 21.5 0.0 0.00036 20.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 AIM23408.1 - 0.00016 22.1 0.0 0.00098 19.5 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.19 AIM23408.1 - 0.00046 19.7 0.0 0.82 9.1 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 AIM23408.1 - 0.00099 19.1 0.0 0.0023 17.9 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_23 PF13476.6 AIM23408.1 - 0.0013 19.3 0.1 0.0024 18.4 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 AIM23408.1 - 0.0039 17.2 0.0 0.0096 15.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 AIM23408.1 - 0.0039 17.1 0.2 0.007 16.3 0.2 1.6 1 1 0 1 1 1 1 NACHT domain AAA_30 PF13604.6 AIM23408.1 - 0.0062 16.3 0.0 0.016 14.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AIM23408.1 - 0.01 16.1 0.5 0.046 14.0 0.5 2.0 1 1 0 1 1 1 0 AAA domain ABC_membrane PF00664.23 AIM23408.1 - 0.01 15.5 14.0 0.21 11.2 0.1 2.1 2 0 0 2 2 2 0 ABC transporter transmembrane region IstB_IS21 PF01695.17 AIM23408.1 - 0.014 15.1 0.6 1 9.1 0.1 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein CRT-like PF08627.10 AIM23408.1 - 0.022 13.7 3.3 0.033 13.1 0.8 2.0 2 0 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like RsgA_GTPase PF03193.16 AIM23408.1 - 0.024 14.6 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase T2SSE PF00437.20 AIM23408.1 - 0.029 13.4 0.0 0.044 12.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein TrkA_C PF02080.21 AIM23408.1 - 0.034 14.0 0.0 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 TrkA-C domain Mg_chelatase PF01078.21 AIM23408.1 - 0.069 12.5 0.1 0.15 11.4 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_ATPase PF09818.9 AIM23408.1 - 0.073 11.9 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class MMR_HSR1 PF01926.23 AIM23408.1 - 0.092 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.6 AIM23408.1 - 0.11 12.0 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 AIM23408.1 - 0.12 12.6 0.1 0.3 11.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AIM23408.1 - 0.13 12.5 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain PapC_C PF13953.6 AIM23408.1 - 0.16 11.8 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 PapC C-terminal domain ATPase_2 PF01637.18 AIM23408.1 - 0.17 11.8 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ATP-synt_ab PF00006.25 AIM23408.1 - 0.19 11.3 0.0 0.32 10.6 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 AIM23408.1 - 0.2 11.1 0.0 0.4 10.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region EIIA-man PF03610.16 AIM23409.1 - 5.8e-27 94.2 0.0 6.6e-27 94.0 0.0 1.0 1 0 0 1 1 1 1 PTS system fructose IIA component EIID-AGA PF03613.14 AIM23410.1 - 2.8e-95 318.5 4.6 3.2e-95 318.3 4.6 1.0 1 0 0 1 1 1 1 PTS system mannose/fructose/sorbose family IID component EII-Sor PF03609.14 AIM23411.1 - 1.3e-73 247.3 27.1 1.4e-73 247.1 27.1 1.0 1 0 0 1 1 1 1 PTS system sorbose-specific iic component PTSIIB_sorb PF03830.15 AIM23412.1 - 8.7e-52 175.3 0.3 9.7e-52 175.1 0.3 1.0 1 0 0 1 1 1 1 PTS system sorbose subfamily IIB component Haem_oxygenas_2 PF14518.6 AIM23412.1 - 0.14 12.0 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Iron-containing redox enzyme GATase PF00117.28 AIM23412.1 - 0.15 11.9 0.0 1.2 8.8 0.0 1.9 1 1 0 2 2 2 0 Glutamine amidotransferase class-I Tagatose_6_P_K PF08013.11 AIM23413.1 - 5.6e-197 654.5 0.1 6.4e-197 654.3 0.1 1.0 1 0 0 1 1 1 1 Tagatose 6 phosphate kinase F_bP_aldolase PF01116.20 AIM23413.1 - 0.025 14.1 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-II TetR_C_15 PF17918.1 AIM23413.1 - 0.28 12.0 2.9 5.3 7.9 0.0 3.4 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain DeoRC PF00455.22 AIM23414.1 - 1e-52 178.3 0.0 2.9e-52 176.9 0.0 1.6 2 0 0 2 2 2 1 DeoR C terminal sensor domain HTH_DeoR PF08220.12 AIM23414.1 - 2e-17 62.6 0.4 5.5e-17 61.3 0.1 1.9 2 0 0 2 2 2 1 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 AIM23414.1 - 5.5e-08 32.6 0.0 1.4e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 HTH domain GntR PF00392.21 AIM23414.1 - 0.0013 18.4 0.0 0.0028 17.3 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family FeoC PF09012.10 AIM23414.1 - 0.0084 16.2 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 FeoC like transcriptional regulator HTH_5 PF01022.20 AIM23414.1 - 0.03 14.2 0.1 0.064 13.1 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family FaeA PF04703.12 AIM23414.1 - 0.13 12.6 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 FaeA-like protein HTH_Mga PF08280.11 AIM23414.1 - 0.16 12.0 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain MFS_1 PF07690.16 AIM23415.1 - 2e-20 73.0 80.7 1.2e-17 63.9 46.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC_tran PF00005.27 AIM23416.1 - 1.3e-24 87.3 0.0 1.9e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIM23416.1 - 8.7e-08 32.3 2.9 0.0018 18.2 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC_membrane PF00664.23 AIM23416.1 - 1.4e-05 24.9 7.6 6.1e-05 22.8 7.7 1.9 1 1 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 AIM23416.1 - 9.2e-05 22.0 0.0 0.069 12.6 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AIM23416.1 - 0.00037 20.9 0.3 0.00098 19.5 0.1 1.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_15 PF13175.6 AIM23416.1 - 0.0023 17.7 0.0 0.067 12.9 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 AIM23416.1 - 0.0067 16.1 0.3 0.017 14.9 0.3 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 AIM23416.1 - 0.065 12.8 0.2 0.18 11.3 0.1 1.9 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 AIM23416.1 - 0.13 12.2 0.1 0.31 11.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 AIM23416.1 - 0.14 12.3 0.0 0.38 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 AIM23416.1 - 0.16 11.9 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_23 PF13476.6 AIM23416.1 - 0.29 11.6 0.2 0.53 10.7 0.2 1.3 1 0 0 1 1 1 0 AAA domain Phage_integrase PF00589.22 AIM23417.1 - 2e-45 154.7 0.2 2.2e-45 154.5 0.2 1.0 1 0 0 1 1 1 1 Phage integrase family GerE PF00196.19 AIM23418.1 - 8e-12 44.5 0.1 1.2e-11 44.0 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AIM23418.1 - 0.019 14.6 1.6 0.022 14.4 0.1 1.8 2 0 0 2 2 2 0 Sigma-70, region 4 Sigma70_r4 PF04545.16 AIM23418.1 - 0.12 11.9 0.1 0.28 10.8 0.1 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 GerE PF00196.19 AIM23419.1 - 6.8e-12 44.8 0.0 1.4e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Response_reg PF00072.24 AIM23419.1 - 5.9e-06 26.4 0.0 1e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Fimbrial PF00419.20 AIM23421.1 - 5.5e-18 65.7 0.2 9.3e-18 65.0 0.2 1.4 1 0 0 1 1 1 1 Fimbrial protein Fimbrial PF00419.20 AIM23422.1 - 6.5e-16 59.0 4.1 7.8e-16 58.7 4.1 1.1 1 0 0 1 1 1 1 Fimbrial protein FimA PF16970.5 AIM23422.1 - 0.00039 20.6 5.1 0.01 16.0 5.1 2.3 1 1 0 1 1 1 1 Type-1 fimbrial protein, A DUF2574 PF10836.8 AIM23422.1 - 0.0034 17.2 0.1 0.007 16.2 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2574) Sugarporin_N PF11471.8 AIM23422.1 - 0.27 11.2 0.7 0.5 10.4 0.7 1.4 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Phage_integrase PF00589.22 AIM23423.1 - 5.3e-40 137.0 0.0 6e-40 136.8 0.0 1.0 1 0 0 1 1 1 1 Phage integrase family EXS PF03124.14 AIM23423.1 - 0.036 13.4 0.1 0.049 13.0 0.1 1.2 1 0 0 1 1 1 0 EXS family PP-binding PF00550.25 AIM23425.1 - 4.6e-10 39.7 0.1 5e-10 39.6 0.1 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ketoacyl-synt_C PF02801.22 AIM23426.1 - 6.6e-33 113.2 0.3 1.3e-32 112.3 0.3 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 AIM23426.1 - 1.2e-28 100.4 6.4 7.2e-28 97.8 4.7 2.3 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.23 AIM23426.1 - 0.0021 17.5 0.3 0.019 14.3 0.1 2.2 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 AIM23426.1 - 0.12 12.1 0.4 0.28 10.8 0.0 1.8 2 0 0 2 2 2 0 Thiolase, C-terminal domain OEP PF02321.18 AIM23427.1 - 3.5e-38 131.3 36.0 5.2e-21 75.3 13.8 2.0 2 0 0 2 2 2 2 Outer membrane efflux protein TFIIF_beta PF02270.15 AIM23427.1 - 0.035 14.2 0.0 0.073 13.2 0.0 1.5 1 0 0 1 1 1 0 TFIIF, beta subunit HTH domain She9_MDM33 PF05546.11 AIM23427.1 - 0.9 9.3 5.1 0.76 9.6 0.3 2.5 2 1 1 3 3 3 0 She9 / Mdm33 family SlyX PF04102.12 AIM23427.1 - 3.5 8.3 10.0 0.42 11.2 1.3 3.2 2 1 0 2 2 2 0 SlyX MacB_PCD PF12704.7 AIM23428.1 - 3.9e-34 118.7 1.6 3.9e-34 118.7 1.6 1.9 2 0 0 2 2 1 1 MacB-like periplasmic core domain ABC_tran PF00005.27 AIM23428.1 - 3.3e-31 108.6 0.0 5.5e-31 107.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter FtsX PF02687.21 AIM23428.1 - 6.4e-09 36.2 2.4 6.4e-09 36.2 2.4 3.2 3 0 0 3 3 3 1 FtsX-like permease family SMC_N PF02463.19 AIM23428.1 - 6.7e-06 25.7 0.1 0.021 14.3 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AIM23428.1 - 0.00026 20.7 0.1 0.00056 19.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AIM23428.1 - 0.00046 20.6 0.1 0.0014 19.0 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AIM23428.1 - 0.0054 16.6 0.1 0.011 15.6 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 AIM23428.1 - 0.0084 15.9 0.1 0.021 14.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 AIM23428.1 - 0.033 13.9 0.8 0.33 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 AIM23428.1 - 0.039 14.0 0.4 0.092 12.8 0.1 1.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_23 PF13476.6 AIM23428.1 - 0.056 13.9 0.0 0.098 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 AIM23428.1 - 0.06 13.1 0.5 1.4 8.6 0.0 2.6 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_22 PF13401.6 AIM23428.1 - 0.073 13.3 0.9 0.56 10.5 0.2 2.6 3 0 0 3 3 3 0 AAA domain ABC_ATPase PF09818.9 AIM23428.1 - 0.085 11.6 0.7 5.1 5.8 0.1 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class DUF5321 PF17254.2 AIM23428.1 - 0.19 11.2 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5321) AAA_33 PF13671.6 AIM23428.1 - 0.2 11.8 1.5 1.3 9.1 0.1 2.4 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 AIM23428.1 - 0.21 11.7 0.2 0.41 10.7 0.2 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain DUF4064 PF13273.6 AIM23428.1 - 3.3 8.0 12.5 1.6 9.1 5.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) HlyD_D23 PF16576.5 AIM23429.1 - 7.7e-17 61.2 7.2 8.8e-17 61.0 6.3 1.6 2 0 0 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AIM23429.1 - 4.8e-12 46.5 6.6 4.9e-07 30.4 0.2 3.3 2 2 0 3 3 3 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AIM23429.1 - 4.1e-10 39.3 16.0 1.7e-09 37.3 4.9 4.9 5 1 0 5 5 5 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AIM23429.1 - 9.6e-07 28.6 0.3 0.0052 16.6 0.0 3.1 3 0 0 3 3 3 2 Biotin-requiring enzyme PTS_EIIA_1 PF00358.20 AIM23429.1 - 1.9e-05 24.4 0.1 0.5 10.1 0.0 3.2 3 0 0 3 3 3 2 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Peptidase_M23 PF01551.22 AIM23429.1 - 0.0001 22.5 0.1 0.2 11.9 0.0 3.0 2 0 0 2 2 2 2 Peptidase family M23 RnfC_N PF13375.6 AIM23429.1 - 0.0013 18.7 2.1 0.081 12.9 0.1 2.6 2 0 0 2 2 2 1 RnfC Barrel sandwich hybrid domain PQQ_2 PF13360.6 AIM23429.1 - 0.04 13.5 0.7 0.09 12.3 0.3 1.9 1 1 0 1 1 1 0 PQQ-like domain HlyD_2 PF12700.7 AIM23429.1 - 0.047 12.4 0.0 0.075 11.8 0.0 1.4 1 0 0 1 1 1 0 HlyD family secretion protein ABC_tran PF00005.27 AIM23430.1 - 1.2e-26 93.8 0.0 2.3e-26 92.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Peptidase_C39 PF03412.15 AIM23430.1 - 1e-19 70.7 0.0 1.7e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase C39 family ABC_membrane PF00664.23 AIM23430.1 - 9.4e-11 41.9 16.0 1.4e-10 41.3 13.6 2.4 2 1 1 3 3 3 1 ABC transporter transmembrane region AAA_21 PF13304.6 AIM23430.1 - 1.4e-08 34.9 0.0 0.00038 20.4 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AIM23430.1 - 8.5e-05 22.2 0.0 0.00022 20.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 AIM23430.1 - 0.00044 19.8 0.1 0.0077 15.7 0.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 AIM23430.1 - 0.0026 17.7 0.0 0.005 16.8 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 AIM23430.1 - 0.0067 16.8 0.8 0.038 14.4 0.7 2.2 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 AIM23430.1 - 0.0095 15.7 0.0 0.39 10.4 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_30 PF13604.6 AIM23430.1 - 0.012 15.4 0.1 0.029 14.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AIM23430.1 - 0.013 15.8 0.2 0.042 14.1 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AIM23430.1 - 0.019 15.5 0.0 0.033 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AIM23430.1 - 0.022 14.4 0.1 0.28 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 AIM23430.1 - 0.035 14.3 0.0 0.071 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Guanylate_cyc_2 PF09778.9 AIM23430.1 - 0.054 12.8 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Guanylylate cyclase STAS_2 PF13466.6 AIM23430.1 - 0.061 13.7 2.2 0.56 10.6 0.1 3.3 3 0 0 3 3 3 0 STAS domain Rad17 PF03215.15 AIM23430.1 - 0.077 12.9 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain SbcCD_C PF13558.6 AIM23430.1 - 0.12 12.6 0.0 0.37 11.0 0.0 1.9 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 AIM23430.1 - 0.15 12.6 0.0 0.6 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain 5_3_exonuc_N PF02739.16 AIM23431.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain DSBA PF01323.20 AIM23432.1 - 6.2e-11 42.4 0.9 2.2e-08 34.1 0.9 2.1 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 AIM23432.1 - 5.6e-05 23.4 0.1 9.3e-05 22.6 0.1 1.3 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_5 PF13743.6 AIM23432.1 - 0.073 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin DUF4762 PF15959.5 AIM23433.1 - 2.8e-19 68.9 0.8 3.1e-19 68.7 0.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4762) LysR_substrate PF03466.20 AIM23434.1 - 2.2e-44 151.3 0.0 2.7e-44 151.0 0.0 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM23434.1 - 4.8e-18 64.9 0.1 8.4e-18 64.1 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_24 PF13412.6 AIM23434.1 - 0.071 12.7 0.0 0.22 11.1 0.0 1.9 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Lactate_perm PF02652.14 AIM23435.1 - 8e-129 430.7 34.6 9.7e-129 430.4 34.6 1.0 1 0 0 1 1 1 1 L-lactate permease FMN_dh PF01070.18 AIM23436.1 - 4.2e-126 420.7 0.1 5e-126 420.4 0.1 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 AIM23436.1 - 3.7e-06 26.2 2.7 2.2e-05 23.6 1.3 2.3 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 AIM23436.1 - 0.00042 19.6 0.8 0.0006 19.1 0.8 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 AIM23436.1 - 0.001 18.4 0.5 0.64 9.3 0.7 2.4 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG NMO PF03060.15 AIM23436.1 - 0.0011 18.4 4.5 0.0017 17.8 4.5 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IGPS PF00218.21 AIM23436.1 - 0.0014 17.9 0.0 0.0032 16.7 0.0 1.6 1 1 1 2 2 2 1 Indole-3-glycerol phosphate synthase His_biosynth PF00977.21 AIM23436.1 - 0.023 14.2 0.1 0.38 10.2 0.1 2.1 1 1 1 2 2 2 0 Histidine biosynthesis protein DHO_dh PF01180.21 AIM23436.1 - 0.094 11.9 0.3 0.15 11.3 0.3 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase MoaF_C PF17409.2 AIM23437.1 - 4.4e-34 116.5 0.2 9.8e-34 115.4 0.1 1.6 2 0 0 2 2 2 1 MoaF C-terminal domain MoaF PF10703.9 AIM23437.1 - 3.2e-20 72.1 0.0 4.3e-18 65.2 0.0 2.1 2 0 0 2 2 2 2 MoaF N-terminal domain HA1 PF18239.1 AIM23437.1 - 0.15 12.0 0.0 3.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Hemagglutinin I MFS_1 PF07690.16 AIM23438.1 - 1.1e-43 149.5 56.2 8.6e-43 146.6 48.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AIM23438.1 - 1.9e-08 33.6 38.8 8.3e-08 31.5 11.8 2.8 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 AIM23438.1 - 5.6e-07 28.7 22.8 2.3e-06 26.7 22.8 1.9 1 1 0 1 1 1 1 MFS_1 like family Nuc_H_symport PF03825.16 AIM23438.1 - 0.00016 20.8 22.1 0.00019 20.6 22.1 1.1 1 0 0 1 1 1 1 Nucleoside H+ symporter DUF4668 PF15701.5 AIM23438.1 - 2.6 7.8 6.6 0.28 11.0 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4668) Bac_luciferase PF00296.20 AIM23439.1 - 4.2e-28 98.7 0.2 7e-28 97.9 0.2 1.3 1 0 0 1 1 1 1 Luciferase-like monooxygenase TPR_7 PF13176.6 AIM23440.1 - 0.047 13.7 0.0 0.097 12.7 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Glyoxalase PF00903.25 AIM23440.1 - 0.13 12.4 0.0 6.4 7.0 0.0 2.1 1 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily BCCT PF02028.17 AIM23441.1 - 2.3e-171 570.5 38.4 2.6e-171 570.3 38.4 1.0 1 0 0 1 1 1 1 BCCT, betaine/carnitine/choline family transporter TetR_C_6 PF13977.6 AIM23442.1 - 7.2e-27 93.9 1.2 7.2e-27 93.9 1.2 2.0 1 1 1 2 2 2 1 BetI-type transcriptional repressor, C-terminal TetR_N PF00440.23 AIM23442.1 - 8.9e-12 44.6 0.1 2e-11 43.5 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_31 PF17940.1 AIM23442.1 - 0.0056 16.9 4.1 0.0085 16.3 0.7 2.2 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain HTH_3 PF01381.22 AIM23442.1 - 0.098 12.7 0.0 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix ABC_membrane PF00664.23 AIM23443.1 - 1.6e-34 119.8 14.7 2e-34 119.5 14.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 AIM23443.1 - 2.1e-34 119.0 0.0 3.4e-34 118.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AIM23443.1 - 3.1e-08 33.3 0.0 1.4e-06 27.9 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AIM23443.1 - 0.00025 21.5 0.2 0.00065 20.1 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 AIM23443.1 - 0.00088 18.6 0.3 0.0024 17.2 0.1 1.8 2 0 0 2 2 2 1 Zeta toxin APS_kinase PF01583.20 AIM23443.1 - 0.0057 16.6 0.1 0.012 15.6 0.1 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_22 PF13401.6 AIM23443.1 - 0.009 16.3 0.0 0.065 13.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 AIM23443.1 - 0.0098 15.5 0.0 0.034 13.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 AIM23443.1 - 0.013 15.5 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 AIM23443.1 - 0.015 15.5 0.0 0.039 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 AIM23443.1 - 0.024 14.7 0.1 0.049 13.7 0.1 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 AIM23443.1 - 0.043 13.6 1.0 0.085 12.6 0.1 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain SbcCD_C PF13558.6 AIM23443.1 - 0.06 13.6 1.3 1.9 8.8 0.2 3.2 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 AIM23443.1 - 0.1 12.4 0.2 0.41 10.4 0.1 1.9 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 AIM23443.1 - 0.13 12.9 0.1 0.54 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 AIM23443.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 AIM23443.1 - 0.15 12.1 0.1 1 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) GyrI-like PF06445.15 AIM23444.1 - 3.8e-32 111.7 0.0 6.6e-32 111.0 0.0 1.4 1 0 0 1 1 1 1 GyrI-like small molecule binding domain HTH_18 PF12833.7 AIM23444.1 - 1.7e-22 79.5 0.4 3.6e-22 78.4 0.4 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AIM23444.1 - 7.6e-19 67.3 0.6 6.4e-09 35.7 0.0 2.9 3 0 0 3 3 3 2 Bacterial regulatory helix-turn-helix proteins, AraC family Cass2 PF14526.6 AIM23444.1 - 2.6e-11 43.9 0.0 4.3e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Integron-associated effector binding protein VHP PF02209.19 AIM23444.1 - 0.049 13.7 0.2 0.13 12.3 0.2 1.7 1 0 0 1 1 1 0 Villin headpiece domain AvrLm4-7 PF18661.1 AIM23444.1 - 0.063 14.3 0.1 0.54 11.3 0.1 2.3 2 0 0 2 2 2 0 Avirulence Effector AvrLm4-7 Peptidase_M23 PF01551.22 AIM23445.1 - 5.9e-31 106.5 1.0 8.5e-31 106.0 1.0 1.2 1 0 0 1 1 1 1 Peptidase family M23 RnfC_N PF13375.6 AIM23445.1 - 0.0023 17.9 0.4 0.55 10.2 0.0 2.5 2 1 0 2 2 2 2 RnfC Barrel sandwich hybrid domain Biotin_lipoyl_2 PF13533.6 AIM23445.1 - 0.017 14.9 0.0 0.11 12.4 0.0 2.3 2 0 0 2 2 2 0 Biotin-lipoyl like PTS_EIIA_1 PF00358.20 AIM23445.1 - 0.14 11.9 0.2 0.27 11.0 0.2 1.5 1 1 0 1 1 1 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 DUF308 PF03729.13 AIM23446.1 - 4e-20 71.9 43.1 1.7e-12 47.5 17.8 3.1 2 1 1 3 3 3 3 Short repeat of unknown function (DUF308) SieB PF14163.6 AIM23446.1 - 0.39 10.2 2.9 1.3 8.5 2.9 1.9 1 0 0 1 1 1 0 Super-infection exclusion protein B DUF3488 PF11992.8 AIM23446.1 - 9.8 5.0 17.9 0.16 10.9 7.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3488) 2OG-Fe_Oxy_2 PF10014.9 AIM23448.1 - 4.7e-51 173.3 0.0 5.3e-51 173.2 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe dioxygenase Aminotran_5 PF00266.19 AIM23449.1 - 3.4e-67 227.0 0.0 1.1e-66 225.4 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 AIM23449.1 - 3.4e-11 42.3 0.2 4.6e-11 41.9 0.2 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 AIM23449.1 - 4.5e-05 22.9 3.1 7.4e-05 22.2 2.6 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 AIM23449.1 - 0.00012 21.4 0.0 0.00018 20.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II BAG PF02179.16 AIM23449.1 - 0.083 13.3 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 BAG domain Phage_head_fibr PF11133.8 AIM23449.1 - 0.12 11.8 0.5 0.18 11.2 0.5 1.2 1 0 0 1 1 1 0 Head fiber protein BCCT PF02028.17 AIM23451.1 - 1.9e-195 650.0 40.5 2.2e-195 649.7 40.5 1.0 1 0 0 1 1 1 1 BCCT, betaine/carnitine/choline family transporter NDUF_B12 PF08122.12 AIM23451.1 - 0.17 11.9 2.7 1.1 9.4 0.1 3.1 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family tRNA-synt_2 PF00152.20 AIM23452.1 - 1.3e-85 287.2 0.4 1.6e-85 287.0 0.4 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 AIM23452.1 - 6.7e-16 58.0 0.1 1.2e-15 57.2 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 AIM23452.1 - 1.6e-06 27.8 1.0 0.015 14.7 0.0 3.1 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) PCRF PF03462.18 AIM23453.1 - 1.2e-43 149.2 1.7 3.1e-43 147.9 0.1 2.0 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 AIM23453.1 - 1.8e-42 143.9 0.5 2.5e-42 143.5 0.5 1.2 1 0 0 1 1 1 1 RF-1 domain DHHA1 PF02272.19 AIM23454.1 - 3e-27 95.7 0.0 5.7e-27 94.8 0.0 1.5 1 0 0 1 1 1 1 DHHA1 domain RecJ_OB PF17768.1 AIM23454.1 - 2.4e-19 69.6 0.0 3.9e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 RecJ OB domain DHH PF01368.20 AIM23454.1 - 3.5e-09 36.8 0.0 5.4e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 DHH family DUF2065 PF09838.9 AIM23454.1 - 0.57 10.2 2.9 0.62 10.1 0.4 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2065) Thioredoxin_2 PF13098.6 AIM23455.1 - 1.7e-29 102.4 0.0 2.4e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain DsbC_N PF10411.9 AIM23455.1 - 1.7e-15 56.2 0.0 5.4e-15 54.6 0.0 1.8 2 0 0 2 2 2 1 Disulfide bond isomerase protein N-terminus Thioredoxin_4 PF13462.6 AIM23455.1 - 3.6e-09 37.0 0.3 0.0026 18.0 0.0 2.6 2 1 1 3 3 3 2 Thioredoxin DSBA PF01323.20 AIM23455.1 - 5e-08 32.9 1.1 0.0023 17.8 0.0 2.9 2 1 1 3 3 3 2 DSBA-like thioredoxin domain Thioredoxin PF00085.20 AIM23455.1 - 0.0004 20.3 0.1 0.16 12.0 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin TraF PF13728.6 AIM23455.1 - 0.0013 18.6 0.0 0.0043 16.9 0.0 1.7 2 0 0 2 2 2 1 F plasmid transfer operon protein Redoxin PF08534.10 AIM23455.1 - 0.013 15.2 0.2 0.032 13.9 0.2 1.7 1 1 0 1 1 1 0 Redoxin Glutaredoxin PF00462.24 AIM23455.1 - 0.11 12.8 0.3 0.3 11.3 0.1 1.9 2 0 0 2 2 2 0 Glutaredoxin Phage_integrase PF00589.22 AIM23456.1 - 1.8e-55 187.4 0.0 2.4e-55 187.0 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 AIM23456.1 - 5.8e-24 84.2 2.6 5.8e-24 84.2 2.6 2.2 2 1 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 AIM23456.1 - 3.2e-06 27.5 0.8 2.7e-05 24.6 0.2 2.5 3 0 0 3 3 3 1 Phage integrase, N-terminal SAM-like domain Flavodoxin_1 PF00258.25 AIM23457.1 - 2.7e-26 92.5 0.0 3.1e-26 92.3 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_3 PF12641.7 AIM23457.1 - 0.024 14.3 0.0 0.049 13.3 0.0 1.6 1 1 1 2 2 2 0 Flavodoxin domain Cpta_toxin PF07254.12 AIM23458.1 - 4.8e-55 185.1 7.8 5.3e-55 184.9 7.8 1.0 1 0 0 1 1 1 1 Membrane-bound toxin component of toxin-antitoxin system DUF4220 PF13968.6 AIM23458.1 - 0.087 12.2 0.3 0.098 12.0 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Sdh5 PF03937.16 AIM23459.1 - 6e-25 87.0 0.3 6.9e-25 86.8 0.3 1.0 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase RE_XamI PF09572.10 AIM23459.1 - 0.057 13.1 0.0 0.068 12.8 0.0 1.1 1 0 0 1 1 1 0 XamI restriction endonuclease GP88 PF17338.2 AIM23459.1 - 0.15 11.5 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 Gene product 88 GerA PF03323.13 AIM23460.1 - 0.2 10.1 0.1 0.24 9.8 0.1 1.0 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein GCV_T PF01571.21 AIM23461.1 - 4.2e-08 32.9 0.0 1.4e-07 31.2 0.0 1.7 1 1 1 2 2 2 1 Aminomethyltransferase folate-binding domain T3SchapCesA PF11439.8 AIM23461.1 - 0.1 12.7 0.0 3.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Type III secretion system filament chaperone CesA DUF2165 PF09933.9 AIM23462.1 - 8.2e-68 227.4 6.0 9.1e-68 227.2 6.0 1.0 1 0 0 1 1 1 1 Predicted small integral membrane protein (DUF2165) HlyIII PF03006.20 AIM23463.1 - 9e-40 136.8 16.6 1e-39 136.6 16.6 1.0 1 0 0 1 1 1 1 Haemolysin-III related CD52 PF15116.6 AIM23463.1 - 0.061 13.4 0.2 0.19 11.8 0.2 1.8 1 0 0 1 1 1 0 CAMPATH-1 antigen Asp4 PF16996.5 AIM23463.1 - 4.2 7.2 9.0 2.6 7.9 0.1 3.2 3 0 0 3 3 3 0 Accessory secretory protein Sec Asp4 HD_3 PF13023.6 AIM23464.1 - 4e-48 163.5 0.2 4e-48 163.5 0.2 1.3 2 0 0 2 2 2 1 HD domain HD_2 PF12917.7 AIM23464.1 - 1.6e-15 57.3 0.2 2.1e-15 56.9 0.2 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 AIM23464.1 - 0.0002 21.5 0.2 0.00033 20.9 0.2 1.4 1 0 0 1 1 1 1 HD domain PfkB PF00294.24 AIM23465.1 - 4e-65 220.1 1.1 4.5e-65 219.9 1.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 AIM23465.1 - 8.9e-16 58.0 0.1 1.3e-15 57.5 0.1 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Carb_kinase PF01256.17 AIM23465.1 - 9.7e-05 22.0 0.1 0.00016 21.2 0.1 1.3 1 0 0 1 1 1 1 Carbohydrate kinase ROK PF00480.20 AIM23466.1 - 2.6e-48 165.0 0.0 3e-48 164.8 0.0 1.0 1 0 0 1 1 1 1 ROK family Glucokinase PF02685.16 AIM23466.1 - 7e-05 22.0 0.1 0.00048 19.2 0.1 2.0 1 1 0 1 1 1 1 Glucokinase BcrAD_BadFG PF01869.20 AIM23466.1 - 0.00062 19.3 0.0 0.0014 18.2 0.0 1.6 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family FGGY_N PF00370.21 AIM23466.1 - 0.13 11.8 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain Hydant_A_N PF05378.13 AIM23466.1 - 0.16 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region Ribul_P_3_epim PF00834.19 AIM23467.1 - 2e-61 206.9 0.0 2.3e-61 206.7 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family BPD_transp_2 PF02653.16 AIM23468.1 - 4.4e-27 94.9 44.8 4.4e-27 94.9 44.8 1.6 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component Pentapeptide_3 PF13576.6 AIM23468.1 - 0.16 12.2 0.6 25 5.1 0.0 2.7 3 0 0 3 3 3 0 Pentapeptide repeats (9 copies) UPF0444 PF15475.6 AIM23468.1 - 1.3 9.3 7.1 0.16 12.2 2.6 1.8 2 0 0 2 2 2 0 Transmembrane protein C12orf23, UPF0444 BPD_transp_2 PF02653.16 AIM23469.1 - 3.1e-38 131.5 39.9 4.6e-38 130.9 39.9 1.2 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component ABC_tran PF00005.27 AIM23470.1 - 5.5e-53 179.2 0.0 5.9e-28 98.1 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 AIM23470.1 - 7.6e-06 25.9 0.4 0.002 18.0 0.0 3.0 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AIM23470.1 - 0.00013 21.7 0.1 0.0014 18.3 0.0 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA PF00004.29 AIM23470.1 - 0.00042 20.7 0.5 0.13 12.7 0.0 2.9 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.19 AIM23470.1 - 0.0017 17.9 0.3 0.1 12.0 0.0 2.5 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 AIM23470.1 - 0.0021 17.8 0.0 0.0093 15.7 0.0 2.1 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 AIM23470.1 - 0.0074 16.2 0.0 0.022 14.6 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_15 PF13175.6 AIM23470.1 - 0.0074 16.0 0.0 0.011 15.5 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain TsaE PF02367.17 AIM23470.1 - 0.011 15.7 0.2 1.7 8.7 0.0 3.0 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 AIM23470.1 - 0.013 15.9 0.2 0.21 11.9 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 AIM23470.1 - 0.016 15.7 0.0 0.034 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 AIM23470.1 - 0.024 13.9 0.0 0.066 12.5 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 AIM23470.1 - 0.03 14.6 3.5 7.6 6.8 0.2 3.3 3 0 0 3 3 3 0 AAA domain ABC_ATPase PF09818.9 AIM23470.1 - 0.052 12.3 0.6 0.38 9.5 0.0 2.2 2 1 0 2 2 2 0 Predicted ATPase of the ABC class MukB PF04310.12 AIM23470.1 - 0.06 13.2 0.0 0.52 10.1 0.0 2.1 2 0 0 2 2 2 0 MukB N-terminal AAA_18 PF13238.6 AIM23470.1 - 0.062 13.8 2.1 0.68 10.5 0.1 2.9 3 1 0 3 3 3 0 AAA domain AAA_28 PF13521.6 AIM23470.1 - 0.09 13.0 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 AIM23470.1 - 0.11 11.7 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 AIM23470.1 - 0.15 12.2 0.4 2.8 8.1 0.1 2.8 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 AIM23470.1 - 0.19 11.6 0.0 2.7 7.8 0.0 2.5 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea ATP-synt_ab PF00006.25 AIM23470.1 - 0.22 11.2 0.1 0.59 9.7 0.0 1.9 1 1 1 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.6 AIM23470.1 - 0.23 11.0 3.5 0.74 9.4 0.0 2.9 4 0 0 4 4 4 0 AAA domain Peripla_BP_4 PF13407.6 AIM23471.1 - 4e-46 157.7 0.3 4.9e-46 157.4 0.3 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 AIM23471.1 - 0.0007 19.1 0.0 0.00087 18.8 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family CoA_binding_2 PF13380.6 AIM23471.1 - 0.11 12.9 0.1 0.32 11.5 0.1 1.8 2 0 0 2 2 2 0 CoA binding domain DeoRC PF00455.22 AIM23472.1 - 2.1e-50 170.8 0.0 2.8e-50 170.4 0.0 1.1 1 0 0 1 1 1 1 DeoR C terminal sensor domain HTH_DeoR PF08220.12 AIM23472.1 - 6.3e-16 57.9 0.4 1.2e-15 57.0 0.4 1.4 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 AIM23472.1 - 0.0027 17.6 0.1 0.0055 16.6 0.1 1.5 1 0 0 1 1 1 1 HTH domain GntR PF00392.21 AIM23472.1 - 0.0028 17.3 0.6 0.0053 16.4 0.6 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family EAP30 PF04157.16 AIM23472.1 - 0.0069 15.7 0.2 1.7 7.9 0.1 2.3 2 0 0 2 2 2 2 EAP30/Vps36 family HTH_20 PF12840.7 AIM23472.1 - 0.028 14.5 0.4 0.059 13.4 0.4 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain MarR_2 PF12802.7 AIM23472.1 - 0.087 12.7 0.6 0.21 11.5 0.6 1.6 1 0 0 1 1 1 0 MarR family RepL PF05732.11 AIM23472.1 - 0.18 11.2 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) BrnA_antitoxin PF14384.6 AIM23473.1 - 1.9e-13 50.7 0.1 3e-13 50.0 0.1 1.3 1 0 0 1 1 1 1 BrnA antitoxin of type II toxin-antitoxin system BrnT_toxin PF04365.13 AIM23474.1 - 1.9e-22 79.4 0.3 2.2e-22 79.2 0.3 1.1 1 0 0 1 1 1 1 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system adh_short_C2 PF13561.6 AIM23475.1 - 1.6e-57 194.8 5.2 1.8e-57 194.6 5.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AIM23475.1 - 8.4e-52 175.5 2.8 1e-51 175.2 2.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AIM23475.1 - 2.9e-15 56.7 3.9 4.4e-15 56.0 3.9 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AIM23475.1 - 0.12 11.8 0.3 0.23 10.9 0.3 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Response_reg PF00072.24 AIM23477.1 - 1.4e-19 70.3 0.0 2e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AIM23477.1 - 3.7e-18 65.4 0.3 6.1e-18 64.7 0.3 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal HATPase_c PF02518.26 AIM23478.1 - 5.6e-17 62.3 0.0 1e-16 61.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AIM23478.1 - 2.5e-12 46.6 2.6 4.6e-12 45.8 2.6 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Acetyltransf_10 PF13673.7 AIM23479.1 - 9.7e-10 38.5 0.0 1.3e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AIM23479.1 - 1.8e-09 37.9 0.0 2.1e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AIM23479.1 - 7.8e-06 26.2 0.0 1.3e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AIM23479.1 - 0.0044 17.2 0.0 0.0057 16.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AIM23479.1 - 0.027 14.6 0.0 0.05 13.7 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_16 PF05301.11 AIM23479.1 - 0.11 12.3 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase, Mec-17 ADH_zinc_N PF00107.26 AIM23480.1 - 1.2e-05 25.3 0.6 5e-05 23.3 0.6 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AIM23480.1 - 0.0044 18.1 0.1 0.016 16.2 0.0 1.9 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AIM23480.1 - 0.064 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain DapB_N PF01113.20 AIM23480.1 - 0.071 13.2 0.0 0.2 11.8 0.0 1.9 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GDC-P PF02347.16 AIM23481.1 - 3.3e-194 645.7 1.4 3e-182 606.3 0.1 3.0 3 0 0 3 3 3 3 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 AIM23481.1 - 3.2e-05 23.4 0.3 8.2e-05 22.0 0.1 1.8 2 0 0 2 2 2 1 Beta-eliminating lyase Aminotran_5 PF00266.19 AIM23481.1 - 0.0007 18.6 0.4 0.0019 17.2 0.1 1.8 2 0 0 2 2 2 1 Aminotransferase class-V GCV_H PF01597.19 AIM23482.1 - 2.6e-45 153.3 0.0 2.8e-45 153.1 0.0 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 AIM23482.1 - 0.0064 16.4 0.1 0.0082 16.1 0.1 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.22 AIM23482.1 - 0.023 14.5 0.1 0.064 13.1 0.1 1.7 2 0 0 2 2 2 0 Biotin-requiring enzyme GCV_T PF01571.21 AIM23483.1 - 3e-82 275.8 0.3 3.8e-82 275.5 0.3 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 AIM23483.1 - 5.9e-11 42.1 0.1 1.3e-10 41.1 0.1 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain POPLD PF08170.12 AIM23483.1 - 0.0054 17.0 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 POPLD (NUC188) domain FAD_binding_3 PF01494.19 AIM23484.1 - 6.3e-31 107.9 0.1 1.2e-30 107.0 0.1 1.4 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 AIM23484.1 - 2.4e-06 26.8 0.4 0.094 11.7 0.1 3.1 3 0 0 3 3 3 2 Lycopene cyclase protein FAD_binding_2 PF00890.24 AIM23484.1 - 0.00019 20.7 0.2 0.00019 20.7 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain SE PF08491.10 AIM23484.1 - 0.00022 20.4 0.0 0.00043 19.4 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase Trp_halogenase PF04820.14 AIM23484.1 - 0.0011 17.9 0.4 0.028 13.3 0.0 2.2 2 0 0 2 2 2 1 Tryptophan halogenase DAO PF01266.24 AIM23484.1 - 0.0012 18.4 3.0 0.0025 17.5 2.4 1.8 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AIM23484.1 - 0.0016 18.7 0.5 0.0058 16.8 0.5 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AIM23484.1 - 0.0088 15.3 0.0 0.21 10.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AIM23484.1 - 0.011 16.3 0.0 0.044 14.3 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 AIM23484.1 - 0.016 14.5 0.0 0.092 12.0 0.1 2.0 2 0 0 2 2 2 0 Thi4 family XdhC_C PF13478.6 AIM23484.1 - 0.14 12.7 0.0 0.32 11.5 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain TrkA_N PF02254.18 AIM23484.1 - 0.19 12.0 0.0 0.41 10.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain DUF2334 PF10096.9 AIM23484.1 - 0.21 11.2 0.0 0.34 10.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Pyr_redox_3 PF13738.6 AIM23484.1 - 0.3 10.3 1.0 0.82 8.9 1.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AIM23484.1 - 0.51 9.0 1.2 1.2 7.7 0.5 1.8 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.19 AIM23485.1 - 3.5e-24 85.7 1.5 5.2e-24 85.1 1.5 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 AIM23485.1 - 6e-06 25.7 0.2 0.075 12.3 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 AIM23485.1 - 3.9e-05 22.7 3.7 0.0073 15.2 0.6 2.4 2 1 0 2 2 2 2 Tryptophan halogenase NAD_binding_9 PF13454.6 AIM23485.1 - 9.6e-05 22.4 0.6 0.29 11.1 0.1 2.7 2 0 0 2 2 2 2 FAD-NAD(P)-binding SE PF08491.10 AIM23485.1 - 0.00014 21.1 0.0 0.00021 20.5 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.24 AIM23485.1 - 0.00021 21.0 1.5 0.021 14.4 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 AIM23485.1 - 0.00095 18.3 1.1 0.88 8.6 0.1 3.0 3 0 0 3 3 3 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 AIM23485.1 - 0.0099 16.1 1.1 0.038 14.2 0.2 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 AIM23485.1 - 0.023 13.4 0.8 2.2 6.9 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein GoLoco PF02188.17 AIM23485.1 - 0.085 12.4 0.6 0.2 11.2 0.6 1.7 1 0 0 1 1 1 0 GoLoco motif Peptidase_M24 PF00557.24 AIM23486.1 - 2e-65 220.4 0.1 2.6e-65 220.0 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 AIM23486.1 - 1.1e-36 125.2 0.0 2.8e-36 124.0 0.0 1.7 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain UPF0149 PF03695.13 AIM23487.1 - 1.1e-37 130.0 4.7 1.3e-37 129.8 4.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0149) ZapA PF05164.13 AIM23488.1 - 3.7e-19 68.9 0.8 4.8e-19 68.6 0.8 1.1 1 0 0 1 1 1 1 Cell division protein ZapA SecA_DEAD PF07517.14 AIM23488.1 - 0.045 13.0 0.4 0.054 12.8 0.4 1.1 1 0 0 1 1 1 0 SecA DEAD-like domain SPACA9 PF15120.6 AIM23488.1 - 0.055 13.3 2.2 0.11 12.2 2.2 1.5 1 1 0 1 1 1 0 Sperm acrosome-associated protein 9 EccE PF11203.8 AIM23488.1 - 0.11 12.8 0.4 0.23 11.8 0.2 1.5 1 1 1 2 2 2 0 Putative type VII ESX secretion system translocon, EccE 5-FTHF_cyc-lig PF01812.20 AIM23489.1 - 6e-48 163.2 0.0 6.8e-48 163.0 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Lant_dehydr_C PF14028.6 AIM23489.1 - 2.1 7.8 5.0 5.7 6.4 1.2 2.0 1 1 1 2 2 2 0 Lantibiotic biosynthesis dehydratase C-term 2-Hacid_dh_C PF02826.19 AIM23490.1 - 1.4e-51 174.4 0.0 2.2e-51 173.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 AIM23490.1 - 3.2e-38 130.4 0.0 4.3e-38 130.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 AIM23490.1 - 4.5e-06 26.3 0.1 1.4e-05 24.8 0.1 1.8 1 0 0 1 1 1 1 ACT domain NAD_binding_2 PF03446.15 AIM23490.1 - 6.9e-05 23.1 0.2 0.00058 20.1 0.1 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT_4 PF13291.6 AIM23490.1 - 0.018 15.6 0.0 0.044 14.4 0.0 1.6 1 0 0 1 1 1 0 ACT domain 3HCDH_N PF02737.18 AIM23490.1 - 0.038 13.9 1.1 1.3 8.8 0.1 2.6 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 AIM23490.1 - 0.045 13.0 0.4 0.47 9.7 0.4 2.2 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.21 AIM23490.1 - 0.091 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Ldh_1_N PF00056.23 AIM23490.1 - 0.14 12.3 0.1 0.32 11.1 0.1 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Rib_5-P_isom_A PF06026.14 AIM23491.1 - 9.5e-59 197.9 0.8 1.1e-58 197.6 0.8 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 AIM23491.1 - 0.00045 20.2 0.1 0.0031 17.4 0.0 2.2 1 1 1 2 2 2 1 DeoR C terminal sensor domain RNase_PH_C PF03725.15 AIM23491.1 - 0.012 15.6 0.8 0.07 13.2 0.0 2.6 2 1 1 3 3 3 0 3' exoribonuclease family, domain 2 HTH_1 PF00126.27 AIM23492.1 - 2e-19 69.3 0.2 7e-19 67.5 0.1 2.0 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 AIM23492.1 - 1e-14 54.4 2.1 1.8e-14 53.6 2.1 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_30 PF13556.6 AIM23492.1 - 0.014 15.2 0.0 0.035 13.9 0.0 1.7 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain SIMPL PF04402.14 AIM23493.1 - 1.1e-44 153.3 8.9 1.3e-44 153.0 8.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF541) LysE PF01810.18 AIM23494.1 - 2.1e-53 180.7 18.1 2.5e-53 180.4 18.1 1.1 1 0 0 1 1 1 1 LysE type translocator DUF485 PF04341.12 AIM23494.1 - 0.06 13.3 8.2 0.099 12.6 1.1 2.9 3 0 0 3 3 3 0 Protein of unknown function, DUF485 ABC2_membrane_2 PF12679.7 AIM23494.1 - 6 6.0 9.5 6.4 6.0 8.7 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein PseudoU_synth_2 PF00849.22 AIM23495.1 - 1e-23 84.2 0.0 1.7e-23 83.5 0.0 1.3 1 1 0 1 1 1 1 RNA pseudouridylate synthase DUF4539 PF15072.6 AIM23495.1 - 0.21 11.7 0.0 3.3 7.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4539) DUF2058 PF09831.9 AIM23496.1 - 8.3e-60 201.9 11.7 9.3e-60 201.7 11.7 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2058) Dynactin_p62 PF05502.13 AIM23496.1 - 0.018 13.8 1.4 0.017 13.9 1.4 1.1 1 0 0 1 1 1 0 Dynactin p62 family RFX1_trans_act PF04589.13 AIM23496.1 - 0.11 12.7 0.2 0.15 12.2 0.2 1.2 1 0 0 1 1 1 0 RFX1 transcription activation region Ndc1_Nup PF09531.10 AIM23496.1 - 0.19 10.4 1.1 0.2 10.3 1.1 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup EMC3_TMCO1 PF01956.16 AIM23496.1 - 3 7.5 11.1 2.5 7.8 9.8 1.5 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like DUF1852 PF08908.11 AIM23497.1 - 2.2e-184 611.9 3.4 2.5e-184 611.7 3.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1852) Meth_synt_2 PF01717.18 AIM23498.1 - 5e-39 134.5 0.0 1.6e-38 132.8 0.0 1.7 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 AIM23498.1 - 5.4e-05 22.8 0.1 0.0014 18.2 0.0 2.3 2 1 0 2 2 2 1 Cobalamin-independent synthase, N-terminal domain CNP1 PF08750.11 AIM23498.1 - 0.001 19.0 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 CNP1-like family URO-D PF01208.17 AIM23498.1 - 0.0097 15.1 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) BtpA PF03437.15 AIM23498.1 - 0.11 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 BtpA family MFS_1 PF07690.16 AIM23499.1 - 4.1e-43 147.7 66.8 7.4e-37 127.1 30.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AIM23499.1 - 1.7e-24 86.5 24.2 3.5e-24 85.5 24.2 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 AIM23499.1 - 4.3e-08 32.8 6.1 4.3e-08 32.8 6.1 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB BT1 PF03092.16 AIM23499.1 - 0.61 8.2 10.7 1.8 6.7 7.5 2.3 2 0 0 2 2 2 0 BT1 family TMF_TATA_bd PF12325.8 AIM23500.1 - 0.033 14.4 3.5 2.4 8.4 0.2 2.8 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.15 AIM23500.1 - 0.52 10.1 6.1 2.7 7.8 0.0 3.4 3 0 0 3 3 3 0 Septum formation initiator DUF2570 PF10828.8 AIM23500.1 - 9.1 6.2 8.7 1.4 8.8 3.9 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2570) MS_channel PF00924.18 AIM23501.1 - 7.5e-57 192.2 3.2 7.5e-57 192.2 3.2 1.5 2 0 0 2 2 2 1 Mechanosensitive ion channel TM_helix PF05552.12 AIM23501.1 - 2.7e-13 49.7 4.1 2.7e-13 49.7 4.1 2.5 2 0 0 2 2 2 1 Conserved TM helix PLDc_2 PF13091.6 AIM23501.1 - 0.014 15.3 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 PLD-like domain DUF1345 PF07077.11 AIM23502.1 - 6.5e-55 185.5 5.3 7.8e-55 185.2 5.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1345) JAMP PF05571.12 AIM23502.1 - 0.19 11.3 5.8 0.13 11.8 0.5 2.1 1 1 1 2 2 2 0 JNK1/MAPK8-associated membrane protein F_bP_aldolase PF01116.20 AIM23503.1 - 3.1e-90 302.5 0.0 3.7e-90 302.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II MR_MLE_C PF13378.6 AIM23503.1 - 0.094 12.3 0.1 0.19 11.3 0.1 1.5 1 0 0 1 1 1 0 Enolase C-terminal domain-like PGK PF00162.19 AIM23504.1 - 9.4e-138 459.2 0.1 1.1e-137 459.1 0.1 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Fucose_iso_C PF02952.17 AIM23504.1 - 0.17 11.6 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 L-fucose isomerase, C-terminal domain Gp_dh_C PF02800.20 AIM23505.1 - 1.6e-52 177.3 0.5 2.1e-52 176.9 0.5 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 AIM23505.1 - 5.5e-34 116.5 0.0 4e-33 113.8 0.0 2.1 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain TrkA_N PF02254.18 AIM23505.1 - 0.021 15.1 0.0 0.057 13.7 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Asp23 PF03780.13 AIM23505.1 - 0.025 15.0 0.0 0.048 14.1 0.0 1.5 1 0 0 1 1 1 0 Asp23 family, cell envelope-related function GFO_IDH_MocA PF01408.22 AIM23505.1 - 0.04 14.7 0.1 0.11 13.3 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 AIM23505.1 - 0.042 14.4 0.3 0.26 11.9 0.0 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_3 PF03447.16 AIM23505.1 - 0.095 13.4 0.3 0.37 11.4 0.0 2.1 2 1 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.20 AIM23505.1 - 0.11 12.7 0.1 0.45 10.6 0.0 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus LysR_substrate PF03466.20 AIM23506.1 - 1.7e-39 135.3 0.8 2.4e-39 134.9 0.8 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM23506.1 - 7.5e-17 61.0 0.7 1.3e-16 60.3 0.7 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_11 PF08279.12 AIM23506.1 - 0.067 13.1 0.2 0.19 11.7 0.0 1.8 2 0 0 2 2 2 0 HTH domain MarR_2 PF12802.7 AIM23506.1 - 0.08 12.8 0.0 0.24 11.3 0.0 1.8 1 0 0 1 1 1 0 MarR family HTH_AsnC-type PF13404.6 AIM23506.1 - 0.087 12.7 0.1 0.23 11.3 0.1 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Iso_dh PF00180.20 AIM23507.1 - 1.3e-86 290.9 0.0 1.5e-86 290.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase BCCT PF02028.17 AIM23508.1 - 8.6e-119 397.1 41.5 1e-118 396.9 41.5 1.0 1 0 0 1 1 1 1 BCCT, betaine/carnitine/choline family transporter NapE PF06796.11 AIM23508.1 - 0.14 11.7 0.0 0.14 11.7 0.0 3.1 4 0 0 4 4 4 0 Periplasmic nitrate reductase protein NapE SLATT_5 PF18160.1 AIM23508.1 - 9.2 5.5 6.1 27 4.0 2.2 2.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Ring_hydroxyl_A PF00848.19 AIM23509.1 - 1.4e-21 77.5 0.3 5.2e-20 72.3 0.3 2.2 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 AIM23509.1 - 4.7e-20 71.3 0.1 8.8e-20 70.5 0.1 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 AIM23509.1 - 0.0081 16.1 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Aldedh PF00171.22 AIM23510.1 - 7.9e-174 578.5 0.0 8.9e-174 578.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TetR_N PF00440.23 AIM23510.1 - 0.06 13.2 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family Fer2 PF00111.27 AIM23511.1 - 1.3e-12 47.5 5.4 2.7e-12 46.4 5.4 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.21 AIM23511.1 - 7.8e-07 29.7 0.0 8e-05 23.3 0.0 2.6 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 AIM23511.1 - 2e-06 28.1 0.0 1.5e-05 25.2 0.0 2.2 3 0 0 3 3 3 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 AIM23511.1 - 1.6e-05 25.0 0.1 0.017 15.2 0.1 2.8 2 1 1 3 3 3 2 Ferric reductase NAD binding domain Fer2_3 PF13085.6 AIM23511.1 - 0.03 14.4 0.4 0.066 13.2 0.4 1.6 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain ABC_tran PF00005.27 AIM23512.1 - 2.7e-35 121.9 0.0 4.4e-35 121.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIM23512.1 - 1.4e-07 31.6 1.0 0.0083 16.0 0.1 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AIM23512.1 - 6.1e-05 22.7 0.0 0.0002 21.0 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AIM23512.1 - 0.00021 21.7 0.3 0.00038 20.9 0.3 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AIM23512.1 - 0.0029 17.9 0.2 0.018 15.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AIM23512.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 AIM23512.1 - 0.011 15.7 0.2 0.054 13.4 0.1 1.9 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.6 AIM23512.1 - 0.014 15.6 0.1 0.021 15.0 0.1 1.5 1 1 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 AIM23512.1 - 0.014 14.2 0.1 1.6 7.4 0.1 2.6 2 1 0 2 2 2 0 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 AIM23512.1 - 0.015 15.2 0.1 0.03 14.2 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase cobW PF02492.19 AIM23512.1 - 0.015 14.9 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 AIM23512.1 - 0.02 15.4 0.0 0.038 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 AIM23512.1 - 0.024 15.1 0.0 0.079 13.4 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 AIM23512.1 - 0.026 14.0 0.1 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein SMC_N PF02463.19 AIM23512.1 - 0.026 13.9 0.0 0.63 9.4 0.0 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 AIM23512.1 - 0.028 13.5 0.1 0.065 12.3 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_25 PF13481.6 AIM23512.1 - 0.046 13.3 0.3 0.14 11.7 0.1 1.8 2 0 0 2 2 2 0 AAA domain DLIC PF05783.11 AIM23512.1 - 0.058 12.2 0.1 0.085 11.7 0.1 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_18 PF13238.6 AIM23512.1 - 0.081 13.5 0.0 0.16 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 AIM23512.1 - 0.1 12.9 0.1 0.19 11.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain TOBE_2 PF08402.10 AIM23512.1 - 0.11 12.7 0.0 0.47 10.7 0.0 2.1 2 0 0 2 2 2 0 TOBE domain NB-ARC PF00931.22 AIM23512.1 - 0.15 11.2 0.1 0.25 10.5 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain TsaE PF02367.17 AIM23512.1 - 0.19 11.7 0.0 0.37 10.8 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 AIM23512.1 - 0.25 11.2 0.0 0.41 10.5 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea BPD_transp_1 PF00528.22 AIM23513.1 - 2e-21 76.5 36.6 5e-12 45.9 16.9 3.7 3 1 1 4 4 4 2 Binding-protein-dependent transport system inner membrane component SBP_bac_8 PF13416.6 AIM23514.1 - 3.5e-19 69.7 2.9 3.5e-19 69.7 2.9 1.5 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 AIM23514.1 - 9.6e-17 61.5 0.2 1.5e-16 60.8 0.2 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AIM23514.1 - 2.8e-14 53.2 0.3 4.7e-14 52.4 0.3 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AIM23514.1 - 2e-12 47.7 6.0 1.8e-11 44.6 6.0 2.3 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein Branch_AA_trans PF05525.13 AIM23515.1 - 1e-05 24.7 0.1 1e-05 24.7 0.1 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport protein Branch_AA_trans PF05525.13 AIM23516.1 - 5.4e-128 427.5 22.8 6e-128 427.4 22.8 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport protein Transketolase_N PF00456.21 AIM23517.1 - 1.5e-170 566.6 0.1 2.4e-170 565.8 0.1 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 AIM23517.1 - 7.1e-45 152.9 0.8 1.5e-44 151.8 0.0 1.9 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 AIM23517.1 - 3.1e-20 72.3 0.5 6.1e-20 71.4 0.2 1.7 2 0 0 2 2 2 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 AIM23517.1 - 4.2e-06 26.2 0.0 0.0063 15.7 0.0 2.5 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 AIM23517.1 - 4.3e-05 23.4 0.4 0.01 15.7 0.4 3.1 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Mur_ligase_C PF02875.21 AIM23517.1 - 0.11 12.8 0.0 0.39 11.0 0.0 1.9 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain CP12 PF02672.15 AIM23517.1 - 0.83 10.4 2.3 9.4 7.1 0.0 3.1 3 0 0 3 3 3 0 CP12 domain Peptidase_M48 PF01435.18 AIM23518.1 - 1.4e-25 90.3 0.1 2.1e-25 89.7 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M48 TPP_enzyme_N PF02776.18 AIM23519.1 - 4.2e-42 143.7 1.7 4.2e-42 143.7 1.7 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 AIM23519.1 - 2.4e-30 105.3 0.5 2.4e-30 105.3 0.5 3.0 3 1 1 4 4 4 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 AIM23519.1 - 1.5e-24 86.3 0.0 2.9e-24 85.3 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain DXP_synthase_N PF13292.6 AIM23519.1 - 0.016 14.4 0.1 0.032 13.5 0.1 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Aldedh PF00171.22 AIM23520.1 - 1.7e-168 560.9 0.0 2e-168 560.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 AIM23520.1 - 0.12 11.4 0.0 0.29 10.1 0.0 1.4 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) DUF108 PF01958.18 AIM23521.1 - 5e-31 106.9 0.3 1.7e-30 105.2 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function DUF108 NAD_binding_3 PF03447.16 AIM23521.1 - 3.9e-12 46.8 0.1 7.2e-12 46.0 0.1 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.20 AIM23521.1 - 0.0064 16.6 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Nif11 PF07862.11 AIM23521.1 - 0.031 14.6 0.3 1.6 9.1 0.0 2.5 2 0 0 2 2 2 0 Nif11 domain Shikimate_DH PF01488.20 AIM23521.1 - 0.033 14.2 0.0 0.056 13.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase T2SSM_b PF10741.9 AIM23521.1 - 0.086 12.7 1.0 0.22 11.3 0.2 2.0 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b IU_nuc_hydro PF01156.19 AIM23521.1 - 0.12 12.0 0.0 0.26 10.8 0.0 1.4 1 1 0 1 1 1 0 Inosine-uridine preferring nucleoside hydrolase adh_short_C2 PF13561.6 AIM23522.1 - 4.1e-44 150.9 0.0 6.2e-44 150.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AIM23522.1 - 8.2e-43 146.1 0.0 9.8e-43 145.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AIM23522.1 - 4e-09 36.6 0.0 5.6e-09 36.2 0.0 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 AIM23522.1 - 0.0085 15.6 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 AIM23522.1 - 0.034 13.5 0.0 0.047 13.0 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Glyco_tran_WecB PF03808.13 AIM23522.1 - 0.049 13.6 0.0 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family SPACA9 PF15120.6 AIM23522.1 - 0.14 11.9 0.0 8.9 6.1 0.0 2.1 2 0 0 2 2 2 0 Sperm acrosome-associated protein 9 Abhydrolase_1 PF00561.20 AIM23523.1 - 1.9e-20 73.6 0.1 1.5e-16 60.8 0.2 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AIM23523.1 - 2.9e-18 67.3 7.8 4e-18 66.8 7.8 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AIM23523.1 - 1.1e-12 47.8 0.1 5.8e-12 45.4 0.1 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 AIM23523.1 - 0.00082 19.3 0.0 0.15 11.9 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase Ndr PF03096.14 AIM23523.1 - 0.0063 15.3 0.0 0.0089 14.8 0.0 1.2 1 0 0 1 1 1 1 Ndr family Abhydrolase_4 PF08386.10 AIM23523.1 - 0.18 11.9 0.0 0.48 10.6 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein Cupin_2 PF07883.11 AIM23524.1 - 7.7e-12 44.8 0.0 1.2e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 AIM23524.1 - 2.9e-06 27.0 0.0 3.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Cupin FdtA PF05523.11 AIM23524.1 - 7.9e-05 22.4 0.0 0.00011 21.9 0.0 1.2 1 0 0 1 1 1 1 WxcM-like, C-terminal ARD PF03079.14 AIM23524.1 - 0.0023 18.1 0.0 0.0036 17.5 0.0 1.2 1 0 0 1 1 1 1 ARD/ARD' family Auxin_BP PF02041.16 AIM23524.1 - 0.0081 15.8 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Auxin binding protein Cupin_3 PF05899.12 AIM23524.1 - 0.011 15.4 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) MFS_1 PF07690.16 AIM23525.1 - 5.1e-53 180.2 69.8 1.1e-44 152.9 44.0 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily PhoLip_ATPase_C PF16212.5 AIM23525.1 - 0.035 13.9 5.0 0.061 13.1 2.6 2.3 1 1 1 2 2 2 0 Phospholipid-translocating P-type ATPase C-terminal MFS_4 PF06779.14 AIM23525.1 - 0.073 12.4 30.1 0.29 10.4 29.6 2.2 2 1 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 AIM23525.1 - 0.13 10.5 0.0 0.13 10.5 0.0 3.2 1 1 2 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family OAD_gamma PF04277.13 AIM23525.1 - 3 8.5 5.8 19 5.9 3.7 2.7 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Pyr_redox_2 PF07992.14 AIM23526.1 - 3.1e-51 174.4 0.0 3.9e-51 174.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 AIM23526.1 - 6.5e-20 71.5 1.5 9.1e-20 71.0 0.3 2.0 2 0 0 2 2 1 1 Reductase C-terminal Pyr_redox PF00070.27 AIM23526.1 - 5.8e-17 62.0 1.7 2.3e-14 53.7 0.0 2.7 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AIM23526.1 - 6.1e-09 36.0 1.7 2.2e-05 24.6 0.2 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 AIM23526.1 - 7.7e-07 28.6 0.2 0.00082 18.6 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 AIM23526.1 - 1.3e-05 24.1 0.4 0.59 8.8 0.0 3.1 3 0 0 3 3 3 3 HI0933-like protein AlaDh_PNT_C PF01262.21 AIM23526.1 - 2e-05 24.0 1.5 0.0023 17.3 0.1 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 AIM23526.1 - 3.1e-05 23.8 6.6 0.0092 15.6 0.6 3.4 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 AIM23526.1 - 0.00015 21.0 0.0 0.11 11.5 0.1 2.7 3 0 0 3 3 3 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 AIM23526.1 - 0.00028 20.3 1.3 0.13 11.5 0.5 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.24 AIM23526.1 - 0.00089 18.4 4.9 1.3 8.0 0.1 3.8 4 1 0 4 4 4 2 FAD binding domain NAD_binding_7 PF13241.6 AIM23526.1 - 0.0013 19.2 0.0 2.1 8.8 0.0 2.4 2 0 0 2 2 2 2 Putative NAD(P)-binding NAD_binding_9 PF13454.6 AIM23526.1 - 0.0026 17.7 1.1 12 5.9 0.1 3.4 2 1 1 3 3 3 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 AIM23526.1 - 0.0034 16.7 0.0 0.027 13.7 0.0 2.3 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 AIM23526.1 - 0.0065 15.8 0.8 0.01 15.2 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 AIM23526.1 - 0.0072 16.2 0.2 0.025 14.5 0.1 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 AIM23526.1 - 0.0094 16.2 0.7 5.1 7.4 0.0 2.7 3 0 0 3 3 2 1 TrkA-N domain PEP-utilizers PF00391.23 AIM23526.1 - 0.021 14.6 0.2 0.3 10.8 0.1 2.4 2 0 0 2 2 2 0 PEP-utilising enzyme, mobile domain XdhC_C PF13478.6 AIM23526.1 - 0.024 15.1 0.0 0.13 12.8 0.0 2.2 2 0 0 2 2 2 0 XdhC Rossmann domain Lycopene_cycl PF05834.12 AIM23526.1 - 0.03 13.4 0.1 3.1 6.7 0.1 3.0 3 0 0 3 3 3 0 Lycopene cyclase protein ThiF PF00899.21 AIM23526.1 - 0.21 10.9 0.1 7.6 5.8 0.0 2.4 2 0 0 2 2 2 0 ThiF family Trp_halogenase PF04820.14 AIM23526.1 - 0.29 9.9 2.1 0.92 8.3 0.2 2.2 2 0 0 2 2 2 0 Tryptophan halogenase FAD_oxidored PF12831.7 AIM23526.1 - 7.3 5.8 6.2 4.7 6.5 0.3 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Glyoxalase PF00903.25 AIM23527.1 - 1.8e-13 50.8 0.3 4.9e-13 49.4 0.2 1.8 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 AIM23527.1 - 4.9e-05 23.6 0.1 0.12 12.6 0.1 3.4 2 2 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 AIM23527.1 - 0.007 17.1 0.0 0.02 15.7 0.0 1.7 2 0 0 2 2 2 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 AIM23527.1 - 0.02 15.0 0.3 0.44 10.7 0.0 2.7 2 1 1 3 3 3 0 Glyoxalase-like domain IclR PF01614.18 AIM23528.1 - 2.5e-20 72.6 0.0 4.4e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 AIM23528.1 - 9.4e-18 63.8 0.2 1.7e-17 62.9 0.2 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain TrmB PF01978.19 AIM23528.1 - 1.2e-05 25.1 0.0 2.4e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR PF01047.22 AIM23528.1 - 0.00051 19.9 0.0 0.0012 18.7 0.0 1.6 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 AIM23528.1 - 0.00062 19.8 0.2 0.0024 17.9 0.1 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.7 AIM23528.1 - 0.029 14.3 0.0 0.069 13.1 0.0 1.6 1 0 0 1 1 1 0 MarR family adh_short_C2 PF13561.6 AIM23529.1 - 7e-55 186.1 1.9 7.9e-55 185.9 1.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AIM23529.1 - 4.3e-46 156.8 1.7 5.1e-46 156.6 1.7 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AIM23529.1 - 1.3e-13 51.2 1.3 2e-13 50.7 1.3 1.2 1 0 0 1 1 1 1 KR domain DUF43 PF01861.16 AIM23529.1 - 0.14 11.4 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain 3HCDH_N PF02737.18 AIM23529.1 - 0.16 11.8 0.3 0.29 11.0 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rieske PF00355.26 AIM23530.1 - 1.5e-18 66.5 0.0 2.5e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Aromatic_hydrox PF11723.8 AIM23530.1 - 0.00037 20.1 0.2 0.0084 15.6 0.0 2.2 2 0 0 2 2 2 1 Homotrimeric ring hydroxylase Ring_hydroxyl_A PF00848.19 AIM23530.1 - 0.03 14.3 1.2 2.3 8.1 0.1 2.1 2 0 0 2 2 2 0 Ring hydroxylating alpha subunit (catalytic domain) DUF1706 PF08020.11 AIM23531.1 - 0.044 13.7 0.0 0.046 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1706) Rieske PF00355.26 AIM23532.1 - 5e-20 71.2 0.0 5.8e-20 71.0 0.0 1.0 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 AIM23532.1 - 3.7e-16 59.0 0.0 4.1e-16 58.8 0.0 1.0 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain MFS_1 PF07690.16 AIM23533.1 - 1.7e-43 148.9 39.5 1.7e-43 148.9 39.5 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 AIM23533.1 - 9.1e-06 24.8 5.4 9.1e-06 24.8 5.4 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 AIM23533.1 - 0.0013 17.1 0.8 0.23 9.7 0.3 2.4 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Sec62 PF03839.16 AIM23533.1 - 0.19 11.2 2.1 0.36 10.3 2.1 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Arginase PF00491.21 AIM23534.1 - 6.6e-85 285.0 0.3 7.9e-85 284.7 0.3 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 AIM23534.1 - 0.22 11.7 0.9 0.33 11.2 0.9 1.3 1 0 0 1 1 1 0 UPF0489 domain Orn_Arg_deC_N PF02784.16 AIM23535.1 - 1.3e-68 231.1 0.0 1.6e-68 230.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Arg_decarb_HB PF17810.1 AIM23535.1 - 1.3e-26 92.6 1.7 2.9e-26 91.5 1.7 1.6 1 0 0 1 1 1 1 Arginine decarboxylase helical bundle domain Arg_decarbox_C PF17944.1 AIM23535.1 - 1.1e-16 61.1 1.3 3.6e-16 59.4 1.3 2.0 1 0 0 1 1 1 1 Arginine decarboxylase C-terminal helical extension S-AdoMet_synt_C PF02773.16 AIM23536.1 - 1.5e-69 232.3 0.0 2.5e-69 231.6 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 AIM23536.1 - 1e-46 158.0 0.0 3.5e-46 156.3 0.0 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 AIM23536.1 - 2.4e-43 146.9 0.1 4.5e-43 146.0 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 AIM23536.1 - 0.078 11.8 0.4 1.2 7.8 0.1 2.4 2 1 1 3 3 3 0 S-adenosylmethionine synthetase (AdoMet synthetase) HOK_GEF PF01848.16 AIM23537.1 - 1.7e-17 62.5 1.6 2e-17 62.3 1.6 1.1 1 0 0 1 1 1 1 Hok/gef family FecCD PF01032.18 AIM23539.1 - 2.3e-136 453.9 80.1 2.6e-70 236.9 38.8 2.1 2 0 0 2 2 2 2 FecCD transport family Crust_neuro_H PF03858.13 AIM23539.1 - 0.086 13.6 0.1 0.23 12.3 0.1 1.7 1 0 0 1 1 1 0 Crustacean neurohormone H ABC-3 PF00950.17 AIM23539.1 - 2.6 7.5 40.1 0.91 9.0 19.9 3.4 2 2 0 3 3 3 0 ABC 3 transport family Peripla_BP_2 PF01497.18 AIM23540.1 - 6.6e-37 127.3 0.0 8e-37 127.1 0.0 1.0 1 0 0 1 1 1 1 Periplasmic binding protein ABC_tran PF00005.27 AIM23541.1 - 5e-32 111.3 0.0 6.5e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AIM23541.1 - 1.2e-07 31.4 0.1 8.6e-05 22.1 0.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AIM23541.1 - 1.9e-06 27.9 0.2 0.0022 17.9 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AIM23541.1 - 0.0019 18.6 0.3 0.0031 17.9 0.3 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AIM23541.1 - 0.0023 17.6 0.1 0.0045 16.7 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain TniB PF05621.11 AIM23541.1 - 0.018 14.5 0.1 0.22 10.9 0.1 2.0 2 0 0 2 2 2 0 Bacterial TniB protein AAA_25 PF13481.6 AIM23541.1 - 0.019 14.5 0.1 0.084 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 AIM23541.1 - 0.026 14.8 0.3 0.28 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 AIM23541.1 - 0.029 14.1 0.1 0.045 13.4 0.1 1.2 1 0 0 1 1 1 0 AAA ATPase domain HD PF01966.22 AIM23541.1 - 0.031 14.5 0.4 0.11 12.8 0.4 1.8 2 0 0 2 2 2 0 HD domain MeaB PF03308.16 AIM23541.1 - 0.033 13.2 0.0 0.043 12.8 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 AIM23541.1 - 0.035 13.8 0.1 0.048 13.4 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AIM23541.1 - 0.035 14.6 0.0 0.053 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AIM23541.1 - 0.048 13.8 0.1 0.087 13.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 AIM23541.1 - 0.056 14.0 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 AIM23541.1 - 0.13 11.1 1.2 3.4 6.4 0.0 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 AIM23541.1 - 0.14 12.1 0.1 0.23 11.4 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase TonB_dep_Rec PF00593.24 AIM23542.1 - 2.1e-64 219.1 38.2 2.1e-64 219.1 38.2 1.9 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 AIM23542.1 - 2.7e-21 76.2 0.0 8.1e-21 74.6 0.0 1.9 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain OMP_b-brl PF13505.6 AIM23542.1 - 0.0049 17.0 30.0 0.013 15.6 5.6 4.6 2 1 3 5 5 5 4 Outer membrane protein beta-barrel domain Transgly PF00912.22 AIM23543.1 - 2.6e-55 186.6 0.0 4.7e-55 185.8 0.0 1.4 1 0 0 1 1 1 1 Transglycosylase PBP1_TM PF14812.6 AIM23543.1 - 4.2e-30 104.0 6.4 8.9e-30 102.9 6.4 1.6 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal UB2H PF14814.6 AIM23543.1 - 1e-29 102.4 0.1 2.2e-29 101.3 0.1 1.6 1 0 0 1 1 1 1 Bifunctional transglycosylase second domain Transpeptidase PF00905.22 AIM23543.1 - 3.5e-23 82.3 0.0 6.3e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain UvrB_inter PF17757.1 AIM23543.1 - 8.8e-07 29.0 0.0 2e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 UvrB interaction domain HrpB_C PF08482.10 AIM23544.1 - 4.3e-54 182.5 0.1 1.1e-53 181.2 0.1 1.8 1 0 0 1 1 1 1 ATP-dependent helicase C-terminal Helicase_C PF00271.31 AIM23544.1 - 5.2e-13 49.3 0.0 1e-12 48.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 AIM23544.1 - 4.1e-09 36.5 0.0 7e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase HA2 PF04408.23 AIM23544.1 - 4.5e-09 36.5 0.1 1.1e-08 35.4 0.1 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) AAA_22 PF13401.6 AIM23544.1 - 0.008 16.5 0.1 0.026 14.8 0.1 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AIM23544.1 - 0.038 13.7 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 AIM23544.1 - 0.059 13.4 0.0 0.14 12.2 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF3136 PF11334.8 AIM23544.1 - 0.12 12.2 0.1 0.72 9.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3136) LigT_PEase PF02834.16 AIM23545.1 - 2.1e-20 72.7 0.9 1.8e-12 47.2 0.1 2.3 2 1 0 2 2 2 2 LigT like Phosphoesterase 2_5_RNA_ligase2 PF13563.6 AIM23545.1 - 1.3e-08 34.9 0.3 1.4e-08 34.8 0.3 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily SfsA PF03749.13 AIM23546.1 - 2.3e-47 160.4 0.0 2.9e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 Sugar fermentation stimulation protein RE domain SfsA_N PF17746.1 AIM23546.1 - 7.8e-23 80.4 0.0 1.4e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 SfsA N-terminal OB domain PDDEXK_4 PF14281.6 AIM23546.1 - 0.078 13.1 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily zf-dskA_traR PF01258.17 AIM23547.1 - 1.4e-10 40.9 2.8 2.4e-10 40.2 2.8 1.3 1 0 0 1 1 1 1 Prokaryotic dksA/traR C4-type zinc finger Not3 PF04065.15 AIM23547.1 - 0.02 14.4 2.4 0.48 9.8 1.8 2.1 1 1 1 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component DZR PF12773.7 AIM23547.1 - 0.054 13.5 0.2 0.095 12.7 0.2 1.3 1 0 0 1 1 1 0 Double zinc ribbon tRNA-synt_1c PF00749.21 AIM23548.1 - 4.5e-46 157.2 0.0 7.3e-45 153.2 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain PolyA_pol_arg_C PF12626.7 AIM23549.1 - 2.1e-43 147.2 4.7 2.1e-43 147.2 4.7 1.9 2 0 0 2 2 2 1 Polymerase A arginine-rich C-terminus PolyA_pol PF01743.20 AIM23549.1 - 1.1e-41 142.2 0.2 2.8e-41 140.9 0.1 1.8 2 0 0 2 2 2 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 AIM23549.1 - 1e-18 66.8 1.5 1.7e-18 66.1 0.3 2.1 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A HPPK PF01288.20 AIM23550.1 - 1.1e-37 129.0 0.0 1.3e-37 128.8 0.0 1.1 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Ribosomal_S6 PF01250.17 AIM23550.1 - 0.23 11.7 0.0 0.39 11.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S6 HATPase_c PF02518.26 AIM23551.1 - 1.3e-17 64.3 0.0 1.9e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AIM23551.1 - 3.5e-11 43.0 1.5 8e-11 41.8 1.5 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain 2CSK_N PF08521.10 AIM23551.1 - 1.8e-07 31.3 0.1 5.3e-07 29.8 0.1 1.8 1 1 0 1 1 1 1 Two-component sensor kinase N-terminal HAMP PF00672.25 AIM23551.1 - 0.0012 19.2 2.3 0.0035 17.7 2.3 1.9 1 0 0 1 1 1 1 HAMP domain HPTransfase PF10090.9 AIM23551.1 - 0.081 12.7 0.4 7.2 6.5 0.0 3.2 3 0 0 3 3 3 0 Histidine phosphotransferase C-terminal domain Response_reg PF00072.24 AIM23552.1 - 2.4e-23 82.4 0.0 3.2e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AIM23552.1 - 8.5e-21 73.8 0.1 2.4e-20 72.4 0.0 1.7 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal GerE PF00196.19 AIM23552.1 - 0.0025 17.3 0.0 2.2 7.9 0.0 2.3 2 0 0 2 2 2 2 Bacterial regulatory proteins, luxR family FleQ PF06490.11 AIM23552.1 - 0.0041 17.5 0.0 0.0058 17.0 0.0 1.3 1 0 0 1 1 1 1 Flagellar regulatory protein FleQ Pantoate_transf PF02548.15 AIM23553.1 - 8.6e-108 359.6 0.0 9.8e-108 359.4 0.0 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase Asp_Glu_race PF01177.22 AIM23553.1 - 0.00019 21.3 0.0 0.00069 19.5 0.0 1.8 2 0 0 2 2 2 1 Asp/Glu/Hydantoin racemase PEP_mutase PF13714.6 AIM23553.1 - 0.0013 18.3 0.1 0.004 16.7 0.0 1.7 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Pantoate_ligase PF02569.15 AIM23554.1 - 1.6e-100 335.7 0.0 1.8e-100 335.6 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Mannitol_dh PF01232.23 AIM23554.1 - 0.024 14.8 0.0 0.46 10.6 0.0 2.1 2 0 0 2 2 2 0 Mannitol dehydrogenase Rossmann domain FAD_syn PF06574.12 AIM23554.1 - 0.11 12.4 0.0 0.86 9.5 0.0 2.1 2 0 0 2 2 2 0 FAD synthetase Asp_decarbox PF02261.16 AIM23555.1 - 1.4e-48 163.6 0.1 1.6e-48 163.4 0.1 1.0 1 0 0 1 1 1 1 Aspartate decarboxylase Polysacc_deac_1 PF01522.21 AIM23556.1 - 1.7e-20 73.2 0.0 3e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase ABC2_membrane PF01061.24 AIM23557.1 - 7.5e-39 133.3 25.7 7.5e-39 133.3 25.7 1.9 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 AIM23557.1 - 3.2e-06 26.5 30.3 3.2e-06 26.5 30.3 1.6 1 1 1 2 2 2 1 ABC-2 family transporter protein CcmB PF03379.13 AIM23557.1 - 0.0016 18.0 9.8 0.0016 18.0 9.8 1.4 1 1 0 1 1 1 1 CcmB protein ABC_tran PF00005.27 AIM23558.1 - 1.8e-32 112.7 0.0 3.2e-32 111.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIM23558.1 - 8.4e-14 52.1 1.4 6.4e-09 36.0 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AIM23558.1 - 8.9e-05 22.3 0.0 0.1 12.3 0.1 2.1 1 1 1 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 AIM23558.1 - 0.00021 20.8 0.1 0.021 14.3 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain DUF4162 PF13732.6 AIM23558.1 - 0.0026 18.5 0.0 0.0064 17.2 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) AAA_29 PF13555.6 AIM23558.1 - 0.0072 16.0 0.2 0.017 14.9 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 AIM23558.1 - 0.016 14.9 0.1 0.049 13.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_27 PF13514.6 AIM23558.1 - 0.019 14.6 0.1 0.042 13.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 AIM23558.1 - 0.025 14.2 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_23 PF13476.6 AIM23558.1 - 0.048 14.2 0.0 0.077 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pro_CA PF00484.19 AIM23559.1 - 2.2e-50 171.0 0.0 2.7e-50 170.7 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Pribosyltran PF00156.27 AIM23560.1 - 2.6e-26 92.0 0.1 3.2e-26 91.7 0.1 1.0 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 AIM23560.1 - 0.0068 15.9 0.0 0.0089 15.5 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Cu-oxidase_3 PF07732.15 AIM23561.1 - 2e-30 105.2 0.2 5.4e-30 103.8 0.0 1.8 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 AIM23561.1 - 2.4e-28 98.6 5.8 2.3e-26 92.2 2.0 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 AIM23561.1 - 6.4e-07 29.6 0.0 5.6e-05 23.3 0.0 2.7 3 0 0 3 3 3 1 Multicopper oxidase TAT_signal PF10518.9 AIM23561.1 - 7.3e-05 22.4 1.1 0.00024 20.8 1.1 1.9 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence T2SS_PulS_OutS PF09691.10 AIM23562.1 - 3.1e-11 43.4 0.0 4.1e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Type II secretion system pilotin lipoprotein (PulS_OutS) Spermine_synth PF01564.17 AIM23563.1 - 4.3e-68 228.4 0.0 5.9e-68 228.0 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 AIM23563.1 - 4.5e-19 68.1 0.2 7.5e-19 67.4 0.2 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 AIM23563.1 - 1.3e-06 29.0 0.0 2.5e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AIM23563.1 - 0.00056 20.5 0.0 0.0017 18.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AIM23563.1 - 0.0025 17.4 0.0 0.0039 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 AIM23563.1 - 0.0031 17.3 0.0 0.0042 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIM23563.1 - 0.049 14.4 0.0 0.093 13.5 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain AdoMet_dc PF02675.15 AIM23564.1 - 2.7e-29 101.5 0.0 5.5e-29 100.5 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine decarboxylase UPF0231 PF06062.11 AIM23565.1 - 5.4e-43 146.1 1.6 6e-43 146.0 1.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0231) Aconitase_2_N PF06434.13 AIM23566.1 - 2.3e-98 327.8 0.0 3.4e-98 327.3 0.0 1.2 1 0 0 1 1 1 1 Aconitate hydratase 2 N-terminus Aconitase_B_N PF11791.8 AIM23566.1 - 6.8e-68 227.6 0.2 1.1e-67 226.8 0.2 1.4 1 0 0 1 1 1 1 Aconitate B N-terminal domain Aconitase PF00330.20 AIM23566.1 - 2.1e-40 139.2 0.0 1.1e-38 133.5 0.0 2.4 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) DUF521 PF04412.13 AIM23566.1 - 0.19 10.4 0.0 0.3 9.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Pyr_redox_2 PF07992.14 AIM23567.1 - 3.5e-62 210.3 4.0 4.7e-62 209.9 4.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 AIM23567.1 - 7.6e-36 122.7 0.0 1.9e-35 121.4 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 AIM23567.1 - 6.3e-18 65.1 4.3 3.6e-15 56.3 0.8 3.0 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AIM23567.1 - 3.6e-09 36.3 0.7 3.5e-05 23.2 0.1 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AIM23567.1 - 8.1e-09 35.0 1.5 4.7e-08 32.5 0.7 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 AIM23567.1 - 1.6e-08 34.3 0.3 3.2e-08 33.3 0.3 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 AIM23567.1 - 1.1e-05 24.4 0.3 0.0018 17.1 0.1 2.3 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 AIM23567.1 - 3.2e-05 23.2 2.0 0.00013 21.2 0.3 2.5 3 0 0 3 3 3 1 FAD binding domain AlaDh_PNT_C PF01262.21 AIM23567.1 - 4.1e-05 23.0 2.2 0.32 10.3 0.2 3.2 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 AIM23567.1 - 0.00015 21.1 0.1 0.00034 19.9 0.1 1.7 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 AIM23567.1 - 0.00019 20.8 0.5 0.0007 18.9 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 AIM23567.1 - 0.00035 20.7 4.5 0.0012 19.0 0.2 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 AIM23567.1 - 0.041 13.8 1.8 4.3 7.2 0.1 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 AIM23567.1 - 0.11 11.5 0.2 0.58 9.2 0.1 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein DAO PF01266.24 AIM23567.1 - 4.1 6.9 10.5 0.34 10.4 0.6 3.0 3 1 1 4 4 4 0 FAD dependent oxidoreductase 2-oxoacid_dh PF00198.23 AIM23568.1 - 3.5e-80 268.8 0.1 4.9e-80 268.3 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 AIM23568.1 - 6.6e-44 147.6 20.4 8.7e-22 76.7 5.5 2.5 2 0 0 2 2 2 2 Biotin-requiring enzyme E3_binding PF02817.17 AIM23568.1 - 1.7e-15 57.0 0.2 5e-15 55.6 0.2 1.9 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 AIM23568.1 - 4.1e-10 39.3 6.1 0.0078 16.0 0.0 4.6 4 0 0 4 4 4 4 Biotin-lipoyl like RnfC_N PF13375.6 AIM23568.1 - 1.3e-09 37.9 5.9 0.00023 21.1 0.5 2.8 2 1 0 2 2 2 2 RnfC Barrel sandwich hybrid domain GCV_H PF01597.19 AIM23568.1 - 4.4e-07 29.8 9.4 0.0021 18.0 1.2 2.4 2 0 0 2 2 2 2 Glycine cleavage H-protein NQRA PF05896.11 AIM23568.1 - 0.00015 21.3 6.1 0.063 12.7 0.5 2.4 1 1 1 2 2 2 2 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) HlyD_D23 PF16576.5 AIM23568.1 - 0.00076 18.8 4.7 0.59 9.3 0.0 3.7 2 2 2 4 4 4 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion PYNP_C PF07831.13 AIM23568.1 - 0.0015 18.2 5.0 9.5 6.0 0.0 4.4 3 1 1 4 4 4 2 Pyrimidine nucleoside phosphorylase C-terminal domain PTS_EIIA_1 PF00358.20 AIM23568.1 - 0.0015 18.3 6.4 3.8 7.3 0.2 4.2 2 2 2 4 4 4 2 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 DUF1223 PF06764.11 AIM23568.1 - 0.11 12.5 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) DUF3597 PF12200.8 AIM23568.1 - 0.21 12.2 12.1 1.4 9.4 2.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) HlyD_3 PF13437.6 AIM23568.1 - 0.37 11.5 8.1 3.5 8.4 0.1 4.0 2 2 2 4 4 4 0 HlyD family secretion protein PDH_E1_M PF17831.1 AIM23569.1 - 1.3e-106 355.3 0.1 2.1e-106 354.7 0.1 1.3 1 0 0 1 1 1 1 Pyruvate dehydrogenase E1 component middle domain Transketolase_N PF00456.21 AIM23569.1 - 4.4e-16 58.7 0.0 2.4e-08 33.3 0.0 2.3 2 0 0 2 2 2 2 Transketolase, thiamine diphosphate binding domain GntR PF00392.21 AIM23570.1 - 1.3e-25 88.8 0.5 2.7e-25 87.8 0.5 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family FCD PF07729.12 AIM23570.1 - 1.4e-18 67.6 9.9 2.9e-18 66.5 9.9 1.6 1 0 0 1 1 1 1 FCD domain MarR PF01047.22 AIM23570.1 - 0.00013 21.8 0.1 0.00099 19.0 0.0 2.3 2 0 0 2 2 2 1 MarR family MarR_2 PF12802.7 AIM23570.1 - 0.00063 19.6 0.6 0.0016 18.3 0.1 2.0 2 0 0 2 2 1 1 MarR family TrmB PF01978.19 AIM23570.1 - 0.0011 18.9 0.0 0.021 14.7 0.0 2.7 3 0 0 3 3 3 1 Sugar-specific transcriptional regulator TrmB PaaX PF07848.12 AIM23570.1 - 0.0026 17.9 0.1 0.0059 16.8 0.1 1.6 1 0 0 1 1 1 1 PaaX-like protein HTH_11 PF08279.12 AIM23570.1 - 0.003 17.5 0.0 0.0084 16.0 0.0 1.8 1 0 0 1 1 1 1 HTH domain HTH_24 PF13412.6 AIM23570.1 - 0.0033 17.0 0.0 0.0066 16.0 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 AIM23570.1 - 0.0035 17.4 0.4 0.02 15.0 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_DeoR PF08220.12 AIM23570.1 - 0.0037 17.0 0.0 0.0091 15.7 0.0 1.6 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain Fe_dep_repress PF01325.19 AIM23570.1 - 0.015 15.5 0.0 0.029 14.5 0.0 1.6 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HATPase_c_2 PF13581.6 AIM23570.1 - 0.042 13.8 0.4 0.067 13.2 0.4 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain HTH_29 PF13551.6 AIM23570.1 - 0.046 13.7 0.3 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn helix Rrf2 PF02082.20 AIM23570.1 - 0.073 13.4 0.1 0.22 11.9 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator HTH_10 PF04967.12 AIM23570.1 - 0.086 12.7 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 HTH DNA binding domain AA_permease PF00324.21 AIM23571.1 - 3.2e-116 388.8 49.6 3.7e-116 388.6 49.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 AIM23571.1 - 5.6e-38 130.9 52.4 7.1e-38 130.5 52.4 1.1 1 0 0 1 1 1 1 Amino acid permease Thioesterase PF00975.20 AIM23571.1 - 0.19 11.8 0.1 0.35 11.0 0.1 1.4 1 0 0 1 1 1 0 Thioesterase domain YobH PF13996.6 AIM23571.1 - 0.4 10.8 4.9 0.96 9.5 0.3 3.0 2 0 0 2 2 2 0 YobH-like protein Cytochrom_C PF00034.21 AIM23572.1 - 1.2e-22 80.8 0.6 3e-08 34.7 0.0 3.7 3 1 0 3 3 3 3 Cytochrome c Cytochrome_CBB3 PF13442.6 AIM23572.1 - 3.3e-20 72.2 4.2 7.2e-09 35.8 0.0 3.9 3 1 0 3 3 3 3 Cytochrome C oxidase, cbb3-type, subunit III Paired_CXXCH_1 PF09699.10 AIM23572.1 - 0.00097 18.8 5.7 3.2 7.6 0.1 3.4 3 0 0 3 3 3 3 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrome_C7 PF14522.6 AIM23572.1 - 0.001 19.0 0.0 11 6.1 0.0 3.2 3 0 0 3 3 3 2 Cytochrome c7 and related cytochrome c DHOR PF06537.11 AIM23572.1 - 0.0045 15.7 0.1 0.4 9.2 0.0 2.6 3 0 0 3 3 3 1 Di-haem oxidoreductase, putative peroxidase Cytochrom_C550 PF14495.6 AIM23572.1 - 0.041 13.6 0.5 4.7 6.9 0.0 3.6 5 0 0 5 5 5 0 Cytochrome c-550 domain GSu_C4xC__C2xCH PF09698.10 AIM23572.1 - 0.36 11.6 8.8 6.3 7.7 0.2 3.6 3 0 0 3 3 3 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) Fer2_2 PF01799.20 AIM23573.1 - 8.8e-23 80.1 1.2 1.6e-22 79.3 0.2 1.8 2 0 0 2 2 2 1 [2Fe-2S] binding domain DHODB_Fe-S_bind PF10418.9 AIM23573.1 - 5.1e-05 23.0 1.6 0.00011 21.9 1.6 1.6 1 0 0 1 1 1 1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Fer2 PF00111.27 AIM23573.1 - 0.00051 19.9 0.9 0.00077 19.4 0.1 1.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain GMP_PDE_delta PF05351.11 AIM23573.1 - 0.17 12.0 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 GMP-PDE, delta subunit Ald_Xan_dh_C2 PF02738.18 AIM23574.1 - 3.5e-77 260.1 0.2 2.4e-55 188.0 0.1 2.2 2 0 0 2 2 2 2 Molybdopterin-binding domain of aldehyde dehydrogenase NTP_transf_3 PF12804.7 AIM23575.1 - 2.7e-23 83.1 3.8 3.4e-23 82.8 3.8 1.0 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 AIM23575.1 - 0.053 13.2 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase TMEM252 PF15664.5 AIM23575.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 252 family XdhC_C PF13478.6 AIM23576.1 - 5.2e-34 117.5 0.1 8.9e-34 116.7 0.1 1.4 1 0 0 1 1 1 1 XdhC Rossmann domain XdhC_CoxI PF02625.16 AIM23576.1 - 1.9e-17 63.2 0.1 4.5e-17 62.0 0.1 1.7 1 0 0 1 1 1 1 XdhC and CoxI family HTH_18 PF12833.7 AIM23577.1 - 3.1e-19 69.0 3.3 7e-19 67.9 1.5 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 AIM23577.1 - 1.6e-13 50.4 1.5 9.4e-06 25.6 0.4 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family GyrI-like PF06445.15 AIM23577.1 - 0.0005 20.4 0.0 0.0014 18.9 0.0 1.6 1 1 1 2 2 2 1 GyrI-like small molecule binding domain Cass2 PF14526.6 AIM23577.1 - 0.0015 18.7 0.0 0.0024 18.0 0.0 1.3 1 0 0 1 1 1 1 Integron-associated effector binding protein SnoaL_2 PF12680.7 AIM23577.1 - 0.11 13.1 0.0 0.52 11.0 0.0 2.0 1 1 1 2 2 2 0 SnoaL-like domain Fumerase_C PF05683.12 AIM23578.1 - 8.6e-90 299.6 0.0 1.4e-89 298.9 0.0 1.4 1 0 0 1 1 1 1 Fumarase C-terminus Fumerase PF05681.14 AIM23578.1 - 1.4e-84 283.8 0.0 1.7e-84 283.4 0.0 1.1 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) SprT-like PF10263.9 AIM23579.1 - 8e-16 57.9 0.0 1.1e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 AIM23579.1 - 3.3e-12 46.1 5.1 6.5e-12 45.1 5.1 1.5 1 0 0 1 1 1 1 SprT-like zinc ribbon domain DUF45 PF01863.17 AIM23579.1 - 0.0054 16.8 0.1 0.0075 16.3 0.1 1.3 1 1 0 1 1 1 1 Protein of unknown function DUF45 FAM101 PF15068.6 AIM23579.1 - 0.054 13.4 0.0 0.86 9.5 0.0 2.0 1 1 1 2 2 2 0 FAM101 family DUF3267 PF11667.8 AIM23579.1 - 0.14 12.5 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative zincin peptidase Endonuclease_1 PF04231.13 AIM23580.1 - 2.1e-41 142.1 6.1 4.1e-41 141.2 6.1 1.4 1 1 0 1 1 1 1 Endonuclease I Methyltrans_RNA PF04452.14 AIM23581.1 - 5.5e-71 238.5 0.0 6.2e-71 238.3 0.0 1.0 1 0 0 1 1 1 1 RNA methyltransferase S1 PF00575.23 AIM23581.1 - 0.037 14.4 0.1 0.09 13.1 0.1 1.7 1 0 0 1 1 1 0 S1 RNA binding domain NST1 PF13945.6 AIM23581.1 - 0.87 9.7 1.8 1.1 9.3 0.5 1.7 2 0 0 2 2 2 0 Salt tolerance down-regulator GSH-S_ATP PF02955.16 AIM23582.1 - 5.1e-80 267.0 0.0 7e-80 266.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain GSH-S_N PF02951.14 AIM23582.1 - 8.8e-48 161.4 0.0 1.4e-47 160.7 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, N-terminal domain RimK PF08443.11 AIM23582.1 - 1.1e-10 41.4 0.0 1.5e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATPgrasp_YheCD PF14398.6 AIM23582.1 - 1.2e-06 28.0 0.0 2.1e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 YheC/D like ATP-grasp ATP-grasp_3 PF02655.14 AIM23582.1 - 0.018 15.1 0.0 0.026 14.6 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_ST PF14397.6 AIM23582.1 - 0.11 11.7 0.0 0.69 9.1 0.0 1.8 1 1 0 2 2 2 0 Sugar-transfer associated ATP-grasp DUF179 PF02622.15 AIM23583.1 - 3.5e-49 166.8 0.0 4e-49 166.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 RuvX PF03652.15 AIM23584.1 - 8.9e-41 139.4 0.0 9.9e-41 139.3 0.0 1.0 1 0 0 1 1 1 1 Holliday junction resolvase TMEM210 PF15195.6 AIM23584.1 - 0.18 12.3 0.0 0.23 11.9 0.0 1.2 1 0 0 1 1 1 0 TMEM210 family T2SSE PF00437.20 AIM23585.1 - 3.6e-43 147.6 0.8 5.6e-43 147.0 0.8 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein TrwB_AAD_bind PF10412.9 AIM23585.1 - 9.3e-06 24.8 0.0 1.7e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.18 AIM23585.1 - 0.00032 20.1 0.1 0.00085 18.7 0.0 1.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.6 AIM23585.1 - 0.00036 20.8 0.0 0.00073 19.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AIM23585.1 - 0.0005 20.5 1.3 0.0005 20.5 1.3 2.0 1 1 1 2 2 2 1 AAA ATPase domain DUF87 PF01935.17 AIM23585.1 - 0.00059 20.0 0.0 0.001 19.2 0.0 1.4 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_29 PF13555.6 AIM23585.1 - 0.001 18.8 0.2 0.002 17.8 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 AIM23585.1 - 0.0012 18.2 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_30 PF13604.6 AIM23585.1 - 0.002 17.9 0.5 0.015 15.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 AIM23585.1 - 0.0021 18.1 0.0 0.0029 17.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ABC_tran PF00005.27 AIM23585.1 - 0.005 17.3 0.0 0.0088 16.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA PF00004.29 AIM23585.1 - 0.0066 16.9 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 AIM23585.1 - 0.0073 16.8 0.1 0.013 16.0 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 AIM23585.1 - 0.0073 16.3 0.0 0.019 15.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain DUF3313 PF11769.8 AIM23585.1 - 0.01 15.6 0.1 0.018 14.9 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3313) AAA_19 PF13245.6 AIM23585.1 - 0.014 15.7 0.2 0.034 14.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 AIM23585.1 - 0.017 15.1 0.0 0.043 13.7 0.0 1.7 1 0 0 1 1 1 0 NACHT domain DUF853 PF05872.12 AIM23585.1 - 0.023 13.3 0.4 0.92 8.0 0.1 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) NTPase_1 PF03266.15 AIM23585.1 - 0.031 14.2 0.2 0.57 10.1 0.2 2.6 1 1 0 1 1 1 0 NTPase DUF2075 PF09848.9 AIM23585.1 - 0.031 13.5 0.0 0.041 13.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 AIM23585.1 - 0.037 13.6 0.6 0.1 12.2 0.6 1.7 1 1 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 AIM23585.1 - 0.041 13.8 0.1 0.12 12.3 0.1 1.9 1 1 0 1 1 1 0 P-loop Nucleotide Kinase3 SRP54 PF00448.22 AIM23585.1 - 0.051 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_18 PF13238.6 AIM23585.1 - 0.083 13.4 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 AIM23585.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 AIM23585.1 - 0.15 11.2 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 AIM23585.1 - 0.17 11.4 0.0 0.49 9.9 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region Microtub_bd PF16796.5 AIM23585.1 - 0.23 11.4 0.0 0.44 10.5 0.0 1.4 1 0 0 1 1 1 0 Microtubule binding RNA_helicase PF00910.22 AIM23585.1 - 0.25 11.8 0.0 0.41 11.1 0.0 1.3 1 0 0 1 1 1 0 RNA helicase HEAT_EZ PF13513.6 AIM23585.1 - 1.3 9.6 6.5 0.18 12.3 0.9 2.5 2 0 0 2 2 1 0 HEAT-like repeat Ala_racemase_N PF01168.20 AIM23586.1 - 1.9e-29 102.9 0.5 2.3e-29 102.6 0.5 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain P5CR_dimer PF14748.6 AIM23587.1 - 3.4e-30 104.3 4.3 6.4e-30 103.4 4.3 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 AIM23587.1 - 1.7e-22 79.8 0.2 4e-22 78.6 0.2 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 AIM23587.1 - 0.00067 19.7 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.22 AIM23587.1 - 0.015 16.2 0.2 0.032 15.1 0.0 1.7 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold PDH PF02153.17 AIM23587.1 - 0.019 14.0 0.0 0.027 13.5 0.0 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase NAD_Gly3P_dh_N PF01210.23 AIM23587.1 - 0.021 14.8 1.8 0.076 13.0 0.9 2.3 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 AIM23587.1 - 0.023 14.9 0.1 0.051 13.8 0.1 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase YGGT PF02325.17 AIM23588.1 - 7.8e-40 135.1 22.8 5.4e-21 74.8 6.3 2.4 1 1 0 2 2 2 2 YGGT family DUF167 PF02594.16 AIM23589.1 - 1.2e-26 92.6 0.2 1.4e-26 92.4 0.2 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 Ham1p_like PF01725.16 AIM23590.1 - 2.1e-63 213.6 0.0 2.4e-63 213.5 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Radical_SAM PF04055.21 AIM23591.1 - 4e-18 66.4 0.0 6.1e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily HemN_C PF06969.16 AIM23591.1 - 5.2e-11 42.5 0.0 1.3e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 HemN C-terminal domain HTH_45 PF14947.6 AIM23591.1 - 0.041 13.9 0.1 0.29 11.1 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix TPR_1 PF00515.28 AIM23591.1 - 0.093 12.6 0.1 0.22 11.4 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 AIM23591.1 - 0.12 12.5 0.1 0.55 10.5 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Fer4_14 PF13394.6 AIM23591.1 - 0.14 12.3 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S single cluster domain DUF29 PF01724.16 AIM23592.1 - 2.1e-44 151.1 1.7 2.3e-44 150.9 1.7 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF29 Peptidase_C10 PF01640.17 AIM23592.1 - 0.068 13.5 0.1 0.082 13.2 0.1 1.1 1 0 0 1 1 1 0 Peptidase C10 family UPF0054 PF02130.17 AIM23592.1 - 0.13 12.1 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein family UPF0054 DUF2884 PF11101.8 AIM23593.1 - 1.1e-47 162.4 3.4 1.3e-47 162.2 3.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2884) Baculo_PEP_C PF04513.12 AIM23593.1 - 0.062 13.3 3.8 4.5 7.3 0.2 2.3 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Latrophilin PF02354.16 AIM23593.1 - 0.067 12.3 0.1 0.09 11.8 0.1 1.3 1 0 0 1 1 1 0 Latrophilin Cytoplasmic C-terminal region CorA PF01544.18 AIM23593.1 - 0.15 11.4 0.8 0.25 10.6 0.8 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Glutaminase PF04960.15 AIM23594.1 - 8.6e-113 376.3 0.0 9.8e-113 376.1 0.0 1.0 1 0 0 1 1 1 1 Glutaminase DUF469 PF04320.14 AIM23595.1 - 2e-43 147.4 0.3 2.2e-43 147.2 0.3 1.0 1 0 0 1 1 1 1 Protein with unknown function (DUF469) Pup PF05639.11 AIM23595.1 - 0.082 13.8 0.0 0.13 13.2 0.0 1.4 1 0 0 1 1 1 0 Pup-like protein Methyltransf_4 PF02390.17 AIM23596.1 - 3.5e-60 202.4 0.0 4.5e-60 202.0 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 AIM23596.1 - 0.00016 22.3 0.0 0.00058 20.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 AIM23596.1 - 0.00017 21.4 0.0 0.00069 19.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 AIM23596.1 - 0.0027 17.2 0.0 0.0035 16.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 AIM23596.1 - 0.04 14.6 0.1 0.26 12.0 0.0 2.3 2 2 0 2 2 2 0 Methyltransferase domain Spermine_synth PF01564.17 AIM23596.1 - 0.16 11.4 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Spermine/spermidine synthase domain NUDIX_4 PF14815.6 AIM23597.1 - 1.5e-22 79.7 0.1 3e-22 78.7 0.1 1.5 1 0 0 1 1 1 1 NUDIX domain HhH-GPD PF00730.25 AIM23597.1 - 3e-22 79.1 0.0 4.4e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 AIM23597.1 - 5.2e-08 32.4 0.0 1.2e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 AIM23597.1 - 0.00026 21.2 4.6 0.00046 20.4 4.6 1.4 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III IMS_HHH PF11798.8 AIM23597.1 - 0.16 12.4 0.0 0.64 10.5 0.0 2.1 1 0 0 1 1 1 0 IMS family HHH motif Iron_traffic PF04362.14 AIM23598.1 - 2.8e-39 132.7 0.2 3.1e-39 132.5 0.2 1.0 1 0 0 1 1 1 1 Bacterial Fe(2+) trafficking DUF5412 PF17428.2 AIM23598.1 - 0.037 13.9 0.2 0.052 13.4 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5412) Mltc_N PF11873.8 AIM23599.1 - 9e-70 233.6 0.0 1.3e-69 233.1 0.0 1.2 1 0 0 1 1 1 1 Membrane-bound lytic murein transglycosylase C, N-terminal domain SLT PF01464.20 AIM23599.1 - 2.7e-33 114.1 0.0 4.3e-33 113.5 0.0 1.3 1 0 0 1 1 1 1 Transglycosylase SLT domain Lysozyme_like PF13702.6 AIM23599.1 - 0.00042 20.0 0.1 0.0075 16.0 0.1 2.2 1 1 0 1 1 1 1 Lysozyme-like SLT_2 PF13406.6 AIM23599.1 - 0.0038 16.5 0.0 0.0074 15.6 0.0 1.4 1 0 0 1 1 1 1 Transglycosylase SLT domain Glucosaminidase PF01832.20 AIM23599.1 - 0.01 16.3 0.2 0.11 13.0 0.2 2.4 1 1 0 1 1 1 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase Phage_lysozyme2 PF18013.1 AIM23599.1 - 0.079 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Phage tail lysozyme OKR_DC_1 PF01276.20 AIM23600.1 - 1.3e-193 643.4 0.0 1.7e-193 643.1 0.0 1.1 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain OKR_DC_1_C PF03711.15 AIM23600.1 - 3.3e-48 163.3 0.2 1.4e-47 161.3 0.1 2.1 2 0 0 2 2 2 1 Orn/Lys/Arg decarboxylase, C-terminal domain OKR_DC_1_N PF03709.15 AIM23600.1 - 1.7e-19 70.1 0.1 4.1e-19 68.9 0.1 1.7 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, N-terminal domain Beta_elim_lyase PF01212.21 AIM23600.1 - 0.0021 17.4 0.0 0.0038 16.6 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase FAD-SLDH PF12318.8 AIM23601.1 - 5.7e-48 163.0 0.9 6.6e-48 162.8 0.9 1.0 1 0 0 1 1 1 1 Membrane bound FAD containing D-sorbitol dehydrogenase TAT_signal PF10518.9 AIM23601.1 - 0.019 14.8 2.8 0.045 13.6 2.8 1.7 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence UbiA PF01040.18 AIM23601.1 - 0.032 13.5 2.2 0.05 12.9 0.1 1.9 2 0 0 2 2 2 0 UbiA prenyltransferase family RP1-2 PF12042.8 AIM23601.1 - 0.73 9.7 7.8 0.066 13.1 3.3 1.4 2 0 0 2 2 2 0 Tubuliform egg casing silk strands structural domain GMC_oxred_C PF05199.13 AIM23602.1 - 6.3e-19 68.9 0.7 7.3e-18 65.5 0.4 2.7 2 1 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.19 AIM23602.1 - 1.9e-05 24.2 0.1 0.00093 18.7 0.1 2.4 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.24 AIM23602.1 - 3.1e-05 23.7 0.0 0.0005 19.8 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AIM23602.1 - 0.0031 17.7 0.2 0.0086 16.3 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 AIM23602.1 - 0.0039 16.3 0.1 0.3 10.1 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 AIM23602.1 - 0.047 12.7 0.7 0.063 12.3 0.1 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_2 PF07992.14 AIM23602.1 - 0.052 12.8 0.1 0.096 11.9 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AIM23602.1 - 0.18 11.0 2.0 0.26 10.5 1.1 1.7 2 0 0 2 2 2 0 FAD binding domain TrkA_N PF02254.18 AIM23602.1 - 0.2 11.9 0.7 6.8 7.0 0.5 2.7 2 0 0 2 2 2 0 TrkA-N domain ApbA PF02558.16 AIM23602.1 - 0.24 11.0 1.2 0.36 10.5 0.3 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 AIM23602.1 - 0.32 11.6 1.5 0.57 10.8 0.7 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AIM23602.1 - 0.37 9.4 1.3 0.63 8.7 1.3 1.3 1 0 0 1 1 1 0 HI0933-like protein Cytochrom_C PF00034.21 AIM23603.1 - 8.4e-23 81.3 0.4 3e-07 31.5 0.0 3.7 3 1 0 3 3 3 3 Cytochrome c Cytochrome_CBB3 PF13442.6 AIM23603.1 - 7.8e-22 77.4 0.1 8.1e-07 29.3 0.0 3.7 3 0 0 3 3 3 3 Cytochrome C oxidase, cbb3-type, subunit III CCP_MauG PF03150.14 AIM23603.1 - 2.8e-05 24.8 0.0 0.025 15.2 0.0 3.2 3 0 0 3 3 3 1 Di-haem cytochrome c peroxidase Cytochrom_C550 PF14495.6 AIM23603.1 - 3.3e-05 23.6 0.9 2.3 8.0 0.1 4.5 4 1 0 4 4 4 2 Cytochrome c-550 domain Cytochrome_C7 PF14522.6 AIM23603.1 - 7e-05 22.7 0.1 7.4 6.7 0.0 3.2 3 0 0 3 3 3 3 Cytochrome c7 and related cytochrome c Paired_CXXCH_1 PF09699.10 AIM23603.1 - 0.00013 21.7 5.9 0.12 12.2 0.1 3.3 3 0 0 3 3 3 2 Doubled CXXCH motif (Paired_CXXCH_1) DHOR PF06537.11 AIM23603.1 - 0.031 12.9 0.3 6.4 5.3 0.0 3.2 4 0 0 4 4 4 0 Di-haem oxidoreductase, putative peroxidase GSu_C4xC__C2xCH PF09698.10 AIM23603.1 - 0.069 13.9 7.6 3 8.7 0.5 3.6 3 0 0 3 3 3 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) ASFV_J13L PF05568.11 AIM23603.1 - 0.21 11.3 1.6 0.48 10.1 0.1 2.3 3 0 0 3 3 3 0 African swine fever virus J13L protein Lactonase PF10282.9 AIM23604.1 - 1.1e-59 202.4 0.0 1.3e-59 202.2 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller PD40 PF07676.12 AIM23604.1 - 1.7e-06 27.8 0.1 0.36 10.8 0.0 4.5 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat SGL PF08450.12 AIM23604.1 - 0.0029 17.2 0.1 2.8 7.5 0.0 3.3 2 2 0 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region WD40 PF00400.32 AIM23604.1 - 0.0032 18.3 0.0 35 5.5 0.0 3.6 3 0 0 3 3 3 0 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 AIM23604.1 - 0.014 14.0 0.2 1.7 7.1 0.0 3.3 2 2 0 3 3 3 0 Cytochrome D1 heme domain TruB_C PF09142.11 AIM23604.1 - 0.042 13.6 0.0 1.2 9.0 0.0 2.9 4 0 0 4 4 4 0 tRNA Pseudouridine synthase II, C terminal Arylesterase PF01731.20 AIM23604.1 - 0.11 12.7 0.0 47 4.3 0.0 3.9 5 0 0 5 5 5 0 Arylesterase DUF5640 PF18692.1 AIM23604.1 - 0.13 12.3 0.0 0.94 9.5 0.0 2.4 3 0 0 3 3 3 0 Family of unknown function (DUF5640) DUF1513 PF07433.11 AIM23604.1 - 0.14 11.2 0.1 24 3.9 0.0 2.7 1 1 2 4 4 4 0 Protein of unknown function (DUF1513) Proteasome_A_N PF10584.9 AIM23604.1 - 0.7 9.6 2.3 62 3.4 0.1 3.8 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Lactonase PF10282.9 AIM23605.1 - 3.7e-20 72.5 0.0 4.1e-20 72.3 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller K_oxygenase PF13434.6 AIM23606.1 - 4.3e-106 354.9 0.0 5e-106 354.7 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 AIM23606.1 - 6.9e-14 51.8 0.0 1.1e-10 41.3 0.0 2.1 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 AIM23606.1 - 9.1e-06 25.7 1.5 0.018 15.1 0.0 3.8 2 1 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 AIM23606.1 - 0.0018 17.6 0.0 0.39 9.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 AIM23606.1 - 0.0037 15.7 0.0 0.046 12.1 0.0 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like ATPgrasp_TupA PF14305.6 AIM23607.1 - 2.7e-43 148.5 0.1 3.1e-43 148.3 0.1 1.0 1 0 0 1 1 1 1 TupA-like ATPgrasp Esterase PF00756.20 AIM23608.1 - 9.1e-18 64.8 0.0 1.2e-17 64.4 0.0 1.1 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 AIM23608.1 - 3.2e-07 30.0 0.0 8.4e-07 28.7 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 AIM23608.1 - 0.00023 20.5 0.1 0.00036 19.9 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AIM23608.1 - 0.00085 19.0 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AIM23608.1 - 0.0069 17.0 6.6 0.0069 17.0 6.6 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 AIM23608.1 - 0.074 12.0 0.0 0.32 9.9 0.0 1.8 1 1 0 1 1 1 0 Chlorophyllase enzyme Acetyltransf_1 PF00583.25 AIM23609.1 - 1.1e-13 51.4 0.0 1.4e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AIM23609.1 - 1.3e-11 44.6 0.0 1.5e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AIM23609.1 - 3.9e-11 43.2 0.0 4.9e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AIM23609.1 - 2.7e-06 27.2 0.0 3.7e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 AIM23609.1 - 0.00054 20.1 0.0 0.00066 19.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AIM23609.1 - 0.024 14.7 0.2 0.042 13.9 0.2 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AIM23609.1 - 0.091 12.9 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Transp_cyt_pur PF02133.15 AIM23610.1 - 2e-23 82.9 33.8 7.5e-22 77.7 33.8 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin HTH_26 PF13443.6 AIM23611.1 - 2.8e-07 30.9 0.0 4.8e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_3 PF01381.22 AIM23611.1 - 0.00096 19.2 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 AIM23611.1 - 0.0065 16.8 0.0 0.01 16.1 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 AIM23611.1 - 0.053 13.6 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain CENP-B_N PF04218.13 AIM23611.1 - 0.057 13.1 0.1 0.2 11.3 0.0 1.9 1 1 1 2 2 2 0 CENP-B N-terminal DNA-binding domain Vut_1 PF02592.15 AIM23612.1 - 1.6e-37 129.1 14.3 1.6e-37 129.1 14.3 1.7 2 0 0 2 2 2 1 Putative vitamin uptake transporter QueF_N PF14819.6 AIM23613.1 - 8.9e-47 158.0 0.0 1.6e-45 153.9 0.0 2.2 2 0 0 2 2 2 1 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term QueF PF14489.6 AIM23613.1 - 4e-35 119.8 0.1 1.9e-27 95.2 0.0 2.2 2 0 0 2 2 2 2 QueF-like protein Phosphoesterase PF04185.14 AIM23614.1 - 3.3e-108 362.1 0.3 1.7e-107 359.7 0.3 2.0 1 1 0 1 1 1 1 Phosphoesterase family DUF756 PF05506.12 AIM23614.1 - 2e-36 124.7 0.5 9.8e-22 77.7 0.3 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF756) Peripla_BP_2 PF01497.18 AIM23615.1 - 9.4e-22 77.7 0.0 1.3e-21 77.3 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein TonB_dep_Rec PF00593.24 AIM23616.1 - 3.3e-50 172.3 51.2 3.5e-49 169.0 51.2 2.0 1 1 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AIM23616.1 - 1.1e-20 74.2 4.0 1.1e-20 74.2 4.0 2.5 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 AIM23616.1 - 1.6e-12 47.1 18.5 3e-12 46.2 18.5 1.4 1 0 0 1 1 1 1 Outer membrane protein beta-barrel family PfkB PF00294.24 AIM23617.1 - 4.6e-70 236.3 0.0 5.2e-70 236.1 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phage_holin_3_1 PF05106.12 AIM23617.1 - 0.24 11.9 2.4 0.41 11.1 0.5 2.1 2 0 0 2 2 2 0 Phage holin family (Lysis protein S) Porin_8 PF16966.5 AIM23618.1 - 7.2e-179 594.4 18.1 8.5e-179 594.2 18.1 1.0 1 0 0 1 1 1 1 Porin-like glycoporin RafY Sugarporin_N PF11471.8 AIM23618.1 - 9.4e-16 57.5 6.0 9.4e-16 57.5 6.0 2.4 1 1 1 2 2 2 1 Maltoporin periplasmic N-terminal extension Tropomyosin PF00261.20 AIM23618.1 - 0.00036 20.0 3.6 0.00053 19.4 3.6 1.1 1 0 0 1 1 1 1 Tropomyosin DUF3847 PF12958.7 AIM23618.1 - 0.0022 18.1 5.0 0.0049 16.9 5.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3847) XhlA PF10779.9 AIM23618.1 - 0.0077 16.4 0.3 0.016 15.4 0.3 1.6 1 0 0 1 1 1 1 Haemolysin XhlA Tropomyosin_1 PF12718.7 AIM23618.1 - 0.092 12.9 6.1 0.15 12.2 6.1 1.2 1 0 0 1 1 1 0 Tropomyosin like ABC_tran_CTD PF16326.5 AIM23618.1 - 0.18 12.1 6.8 0.41 10.9 6.8 1.6 1 0 0 1 1 1 0 ABC transporter C-terminal domain Uso1_p115_C PF04871.13 AIM23618.1 - 0.38 11.1 5.8 0.65 10.4 5.8 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Nup54 PF13874.6 AIM23618.1 - 0.48 10.5 7.7 0.89 9.7 7.7 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 ERM PF00769.19 AIM23618.1 - 2.4 7.9 14.3 3.5 7.4 14.3 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF4192 PF13830.6 AIM23618.1 - 3.8 7.5 13.7 9.4 6.2 13.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) PTS_EIIC PF02378.18 AIM23619.1 - 2.5e-46 158.2 38.4 2.5e-46 158.2 38.4 1.6 2 0 0 2 2 2 1 Phosphotransferase system, EIIC PTS_EIIB PF00367.20 AIM23619.1 - 1.2e-14 53.5 0.1 2.2e-14 52.6 0.1 1.5 1 0 0 1 1 1 1 phosphotransferase system, EIIB Glyco_hydro_32N PF00251.20 AIM23620.1 - 8.3e-98 327.7 0.0 9.8e-98 327.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 AIM23620.1 - 1.7e-08 34.6 0.0 2.7e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_43 PF04616.14 AIM23620.1 - 0.11 11.8 0.0 0.51 9.6 0.0 1.9 2 0 0 2 2 2 0 Glycosyl hydrolases family 43 LacI PF00356.21 AIM23621.1 - 1.5e-17 63.1 0.0 4e-17 61.7 0.0 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_3 PF13377.6 AIM23621.1 - 6.4e-13 49.4 0.0 1.4e-11 45.0 0.0 2.2 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_4 PF13407.6 AIM23621.1 - 1.5e-10 41.1 0.0 1.8e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 AIM23621.1 - 1e-09 38.2 0.0 1.2e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family HTH_19 PF12844.7 AIM23621.1 - 0.0019 18.2 0.0 1.7 8.7 0.0 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_10 PF04967.12 AIM23621.1 - 0.03 14.1 0.1 0.065 13.1 0.1 1.4 1 0 0 1 1 1 0 HTH DNA binding domain HTH_IclR PF09339.10 AIM23621.1 - 0.11 12.3 0.0 0.37 10.6 0.0 2.0 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_24 PF13412.6 AIM23621.1 - 0.12 11.9 0.0 0.32 10.6 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_3 PF01381.22 AIM23621.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix ExbD PF02472.16 AIM23622.1 - 1e-31 109.8 0.6 1.2e-31 109.5 0.6 1.0 1 0 0 1 1 1 1 Biopolymer transport protein ExbD/TolR NETI PF14044.6 AIM23622.1 - 0.046 13.5 0.1 3 7.6 0.0 2.3 2 0 0 2 2 2 0 NETI protein MotA_ExbB PF01618.16 AIM23623.1 - 1.5e-33 115.2 1.3 2.4e-33 114.6 0.4 1.8 2 0 0 2 2 2 1 MotA/TolQ/ExbB proton channel family LapA_dom PF06305.11 AIM23623.1 - 2.2 8.1 8.0 0.084 12.7 1.6 1.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Cys_Met_Meta_PP PF01053.20 AIM23624.1 - 7.2e-111 370.4 0.0 8.1e-111 370.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.11 AIM23624.1 - 0.011 14.3 0.0 0.022 13.3 0.0 1.5 1 1 0 1 1 1 0 Methionine gamma-lyase SNARE_assoc PF09335.11 AIM23625.1 - 8.3e-20 71.5 6.2 8.3e-20 71.5 6.2 1.7 2 0 0 2 2 2 1 SNARE associated Golgi protein Transport_MerF PF11431.8 AIM23625.1 - 0.21 11.5 9.5 0.31 10.9 1.1 3.4 3 0 0 3 3 3 0 Membrane transport protein MerF LysR_substrate PF03466.20 AIM23626.1 - 4.9e-48 163.3 4.5 7.8e-48 162.6 4.5 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM23626.1 - 1.1e-17 63.7 1.8 1.1e-17 63.7 1.8 2.0 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AIM23626.1 - 0.024 14.4 0.5 0.061 13.1 0.2 1.8 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain MarR_2 PF12802.7 AIM23626.1 - 0.055 13.4 1.1 0.23 11.4 0.2 2.4 2 0 0 2 2 2 0 MarR family MarR PF01047.22 AIM23626.1 - 0.13 12.2 0.1 0.52 10.3 0.1 2.0 2 0 0 2 2 2 0 MarR family ADH_zinc_N PF00107.26 AIM23627.1 - 4.2e-27 94.7 1.8 6.6e-27 94.0 1.8 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AIM23627.1 - 7.4e-17 62.6 0.3 2.1e-16 61.2 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AIM23627.1 - 3.6e-10 39.7 0.0 9.3e-10 38.4 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain NAD_binding_7 PF13241.6 AIM23627.1 - 0.084 13.3 0.1 0.15 12.5 0.1 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding AraC_N PF06719.13 AIM23628.1 - 2.1e-42 144.3 0.0 2.9e-42 143.8 0.0 1.2 1 0 0 1 1 1 1 AraC-type transcriptional regulator N-terminus HTH_18 PF12833.7 AIM23628.1 - 3.7e-21 75.2 0.7 1.1e-20 73.7 0.2 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 AIM23628.1 - 9.3e-17 60.7 0.0 1.8e-08 34.3 0.0 2.5 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Fe-ADH PF00465.19 AIM23629.1 - 1.2e-88 297.5 0.3 1.4e-88 297.2 0.3 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 AIM23629.1 - 5e-11 42.8 0.4 7.2e-07 29.2 0.1 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.20 AIM23629.1 - 0.013 14.7 0.1 0.32 10.1 0.0 2.6 3 0 0 3 3 3 0 3-dehydroquinate synthase Aldo_ket_red PF00248.21 AIM23630.1 - 9.4e-47 159.6 0.0 3.2e-35 121.7 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family SLT PF01464.20 AIM23631.1 - 1.4e-27 95.7 0.1 2e-27 95.2 0.1 1.2 1 0 0 1 1 1 1 Transglycosylase SLT domain Glucosaminidase PF01832.20 AIM23631.1 - 0.0013 19.2 0.0 0.0017 18.8 0.0 1.3 1 1 0 1 1 1 1 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase SLT_2 PF13406.6 AIM23631.1 - 0.0032 16.7 0.0 0.0049 16.1 0.0 1.3 1 0 0 1 1 1 1 Transglycosylase SLT domain Phage_lysozyme2 PF18013.1 AIM23631.1 - 0.014 15.4 0.0 0.031 14.3 0.0 1.5 1 1 0 1 1 1 0 Phage tail lysozyme Lysozyme_like PF13702.6 AIM23631.1 - 0.14 11.9 0.0 0.33 10.6 0.0 1.7 1 1 0 1 1 1 0 Lysozyme-like Radical_SAM_N PF08497.10 AIM23632.1 - 8.1e-148 491.5 0.0 1.2e-147 490.9 0.0 1.3 1 0 0 1 1 1 1 Radical SAM N-terminal DUF3362 PF11842.8 AIM23632.1 - 3.1e-43 147.7 0.4 5.5e-43 146.9 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3362) Radical_SAM PF04055.21 AIM23632.1 - 4.5e-20 72.7 0.0 1.8e-19 70.8 0.1 1.9 2 0 0 2 2 2 1 Radical SAM superfamily B12-binding PF02310.19 AIM23632.1 - 0.00049 20.1 0.0 0.091 12.8 0.0 2.6 2 0 0 2 2 2 2 B12 binding domain UTRA PF07702.13 AIM23633.1 - 7.2e-31 106.9 0.1 1.3e-30 106.1 0.0 1.4 2 0 0 2 2 2 1 UTRA domain GntR PF00392.21 AIM23633.1 - 7.5e-15 54.3 1.2 1.7e-14 53.2 1.2 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_Crp_2 PF13545.6 AIM23633.1 - 1.2e-06 28.4 0.5 3.2e-06 27.0 0.5 1.9 1 1 0 1 1 1 1 Crp-like helix-turn-helix domain Crp PF00325.20 AIM23633.1 - 0.00014 21.5 0.7 0.00072 19.2 0.2 2.2 2 0 0 2 2 2 1 Bacterial regulatory proteins, crp family MarR PF01047.22 AIM23633.1 - 0.00016 21.5 0.0 0.00037 20.4 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_11 PF08279.12 AIM23633.1 - 0.00052 19.9 0.0 0.0013 18.7 0.0 1.7 1 0 0 1 1 1 1 HTH domain RepL PF05732.11 AIM23633.1 - 0.00052 19.5 0.0 0.00085 18.8 0.0 1.3 1 0 0 1 1 1 1 Firmicute plasmid replication protein (RepL) MarR_2 PF12802.7 AIM23633.1 - 0.00073 19.4 0.1 0.0018 18.1 0.1 1.7 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 AIM23633.1 - 0.00077 19.0 0.1 0.0016 17.9 0.1 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_36 PF13730.6 AIM23633.1 - 0.0031 17.4 0.0 0.006 16.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain LexA_DNA_bind PF01726.16 AIM23633.1 - 0.0031 17.2 0.1 0.015 15.1 0.1 2.0 1 1 1 2 2 2 1 LexA DNA binding domain TrmB PF01978.19 AIM23633.1 - 0.0043 16.9 0.1 0.011 15.6 0.1 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_41 PF14502.6 AIM23633.1 - 0.0057 16.3 0.1 0.013 15.1 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain Rrf2 PF02082.20 AIM23633.1 - 0.0078 16.5 0.1 0.014 15.7 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulator HTH_20 PF12840.7 AIM23633.1 - 0.015 15.4 1.5 0.044 13.8 0.0 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_29 PF13551.6 AIM23633.1 - 0.088 12.8 0.2 0.67 10.0 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn helix HTH_17 PF12728.7 AIM23633.1 - 0.15 12.3 0.3 5.1 7.4 0.0 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain Fe_dep_repress PF01325.19 AIM23633.1 - 0.18 12.1 0.1 0.55 10.5 0.0 1.8 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain HTH_8 PF02954.19 AIM23633.1 - 0.64 9.8 4.8 0.66 9.8 0.1 3.1 4 0 0 4 4 4 0 Bacterial regulatory protein, Fis family Transp_cyt_pur PF02133.15 AIM23634.1 - 6.4e-41 140.5 40.4 7.6e-41 140.3 40.4 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin TNFR_16_TM PF18422.1 AIM23634.1 - 5.9 6.9 8.4 6.4 6.8 2.6 3.4 3 0 0 3 3 3 0 Tumor necrosis factor receptor member 16 trans-membrane domain PfkB PF00294.24 AIM23635.1 - 3e-41 141.7 0.0 3.6e-41 141.4 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Nuc_H_symport PF03825.16 AIM23636.1 - 2.6e-159 530.5 31.4 2.9e-159 530.3 31.4 1.0 1 0 0 1 1 1 1 Nucleoside H+ symporter MFS_1_like PF12832.7 AIM23636.1 - 3.9e-23 82.0 29.2 3.9e-23 82.0 29.2 1.9 2 1 0 2 2 2 1 MFS_1 like family MFS_1 PF07690.16 AIM23636.1 - 1e-16 60.8 68.0 2.1e-09 36.8 19.8 2.9 2 1 1 3 3 3 3 Major Facilitator Superfamily LacY_symp PF01306.19 AIM23636.1 - 1.3e-10 40.7 25.8 1.7e-10 40.2 25.8 1.1 1 0 0 1 1 1 1 LacY proton/sugar symporter PNP_UDP_1 PF01048.20 AIM23637.1 - 3.8e-42 144.2 1.3 4.3e-42 144.0 1.3 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily LysR_substrate PF03466.20 AIM23638.1 - 4.7e-38 130.7 2.4 7.4e-38 130.0 2.4 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM23638.1 - 1.3e-23 82.7 0.4 3.1e-23 81.5 0.1 1.9 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_24 PF13412.6 AIM23638.1 - 0.00036 20.0 0.0 0.0015 18.0 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 AIM23638.1 - 0.0015 18.6 0.0 0.0058 16.7 0.0 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_34 PF13601.6 AIM23638.1 - 0.011 15.9 0.0 0.028 14.6 0.0 1.8 1 1 0 1 1 1 0 Winged helix DNA-binding domain HTH_5 PF01022.20 AIM23638.1 - 0.016 15.0 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 AIM23638.1 - 0.069 13.0 0.0 0.3 11.0 0.0 2.0 2 0 0 2 2 2 0 MarR family Cu-oxidase_3 PF07732.15 AIM23639.1 - 2.4e-24 85.6 0.9 1.1e-23 83.5 0.0 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 AIM23639.1 - 3.5e-15 55.9 0.0 8.3e-15 54.7 0.0 1.6 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase PF00394.22 AIM23639.1 - 0.00011 22.4 0.0 0.0003 20.9 0.0 1.7 1 0 0 1 1 1 1 Multicopper oxidase TAT_signal PF10518.9 AIM23639.1 - 0.0059 16.4 0.1 0.013 15.3 0.1 1.6 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence Acyltransferase PF01553.21 AIM23640.1 - 5.8e-33 113.4 0.0 8.5e-33 112.8 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase DNA_topoisoIV PF00521.20 AIM23641.1 - 5.9e-134 447.2 0.0 7e-134 446.9 0.0 1.0 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.13 AIM23641.1 - 1.2e-13 50.3 0.0 3.7e-07 29.5 0.0 3.0 3 0 0 3 3 3 2 DNA gyrase C-terminal domain, beta-propeller DUF4890 PF16231.5 AIM23641.1 - 0.027 14.9 0.5 0.07 13.6 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4890) Flavodoxin_2 PF02525.17 AIM23642.1 - 5.5e-37 127.4 0.0 7.5e-37 127.0 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold ABM PF03992.16 AIM23643.1 - 6.8e-19 67.8 0.1 9.3e-19 67.3 0.1 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase LysR_substrate PF03466.20 AIM23644.1 - 1.4e-39 135.7 3.1 1.8e-39 135.3 3.1 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM23644.1 - 5.4e-17 61.5 2.2 1.1e-16 60.5 2.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family DUF596 PF04591.12 AIM23644.1 - 0.019 15.1 0.0 0.039 14.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF596 WASH-7_mid PF14744.6 AIM23644.1 - 0.031 13.4 0.0 0.048 12.7 0.0 1.2 1 0 0 1 1 1 0 WASH complex subunit 7 CM_2 PF01817.21 AIM23644.1 - 0.047 14.0 0.2 0.21 12.0 0.0 2.1 2 0 0 2 2 2 0 Chorismate mutase type II DNA_gyraseB PF00204.25 AIM23645.1 - 7.8e-40 136.2 0.0 1.4e-39 135.3 0.0 1.3 1 0 0 1 1 1 1 DNA gyrase B DNA_gyraseB_C PF00986.21 AIM23645.1 - 2.2e-23 82.2 0.8 6.7e-23 80.6 0.4 1.9 2 0 0 2 2 2 1 DNA gyrase B subunit, carboxyl terminus HATPase_c PF02518.26 AIM23645.1 - 7.6e-17 61.8 0.1 1.4e-16 61.0 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 AIM23645.1 - 4e-11 43.1 0.0 7.6e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Toprim domain HATPase_c_3 PF13589.6 AIM23645.1 - 0.0017 18.2 0.0 0.0032 17.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TOPRIM_C PF16898.5 AIM23645.1 - 0.076 13.3 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 C-terminal associated domain of TOPRIM UPF0227 PF05728.12 AIM23646.1 - 2e-69 233.3 0.0 2.3e-69 233.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_6 PF12697.7 AIM23646.1 - 0.037 14.6 0.5 0.11 13.1 0.2 1.7 1 1 1 2 2 2 0 Alpha/beta hydrolase family Metallophos PF00149.28 AIM23647.1 - 7.9e-20 72.2 1.1 1.2e-19 71.6 1.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AIM23647.1 - 1.2e-09 38.6 1.9 3e-09 37.3 1.9 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF1249 PF06853.12 AIM23648.1 - 2.1e-41 140.6 0.4 2.5e-41 140.4 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1249) HigB_toxin PF09907.9 AIM23648.1 - 0.074 13.3 0.0 2.8 8.2 0.0 2.4 1 1 1 2 2 2 0 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system LuxS PF02664.15 AIM23648.1 - 0.075 12.7 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 S-Ribosylhomocysteinase (LuxS) NUDIX PF00293.28 AIM23649.1 - 7.7e-11 42.2 0.3 1.3e-10 41.5 0.2 1.4 1 1 0 1 1 1 1 NUDIX domain Glyco_tranf_2_3 PF13641.6 AIM23649.1 - 0.0089 15.9 0.1 0.011 15.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF3892 PF13031.6 AIM23649.1 - 0.15 12.7 0.0 18 6.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3892) OEP PF02321.18 AIM23650.1 - 9.7e-63 211.4 33.1 4.6e-34 117.9 11.4 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein Ribosomal_S5_C PF03719.15 AIM23650.1 - 0.09 12.2 0.2 0.29 10.6 0.2 1.9 1 0 0 1 1 1 0 Ribosomal protein S5, C-terminal domain Sigma54_activat PF00158.26 AIM23651.1 - 8.2e-35 120.0 0.0 1.4e-34 119.2 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AIM23651.1 - 2.2e-19 69.9 0.1 4.1e-19 69.1 0.1 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 AIM23651.1 - 4.3e-12 45.6 0.9 1.4e-11 44.0 0.9 2.0 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family PAS PF00989.25 AIM23651.1 - 4.3e-11 42.8 0.0 2.8e-10 40.2 0.0 2.3 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 AIM23651.1 - 1.8e-07 31.4 0.1 0.00089 19.5 0.0 3.0 3 0 0 3 3 3 2 PAS fold GAF PF01590.26 AIM23651.1 - 0.00017 22.2 0.5 0.0028 18.3 0.1 3.1 3 2 2 5 5 5 1 GAF domain PAS_8 PF13188.7 AIM23651.1 - 0.0015 18.5 0.0 0.0053 16.7 0.0 2.0 1 0 0 1 1 1 1 PAS domain HTH_17 PF12728.7 AIM23651.1 - 0.0032 17.6 0.0 0.047 13.9 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain AAA_5 PF07728.14 AIM23651.1 - 0.0043 17.1 0.2 0.019 14.9 0.0 2.2 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 AIM23651.1 - 0.012 15.0 0.6 0.17 11.3 0.0 2.5 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI PAS_7 PF12860.7 AIM23651.1 - 0.018 15.2 0.0 0.058 13.6 0.0 1.9 1 0 0 1 1 1 0 PAS fold RWP-RK PF02042.15 AIM23651.1 - 0.019 14.9 0.1 0.083 12.9 0.0 2.1 2 0 0 2 2 2 0 RWP-RK domain AAA_16 PF13191.6 AIM23651.1 - 0.023 15.1 1.8 0.052 13.9 0.2 2.3 2 0 0 2 2 2 0 AAA ATPase domain PAS_9 PF13426.7 AIM23651.1 - 0.038 14.3 0.0 0.13 12.6 0.0 1.9 1 0 0 1 1 1 0 PAS domain HTH_50 PF18024.1 AIM23651.1 - 0.038 13.6 0.1 0.21 11.2 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain DUF2380 PF09533.10 AIM23651.1 - 0.086 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Predicted lipoprotein of unknown function (DUF2380) PEP-utilisers_N PF05524.13 AIM23652.1 - 7.1e-28 97.1 0.5 7.1e-28 97.1 0.5 2.4 2 0 0 2 2 2 1 PEP-utilising enzyme, N-terminal EIIA-man PF03610.16 AIM23652.1 - 2.2e-25 89.1 2.4 4.3e-25 88.2 1.7 1.9 2 0 0 2 2 2 1 PTS system fructose IIA component PTS-HPr PF00381.19 AIM23652.1 - 8.7e-21 74.0 0.3 2.9e-20 72.3 0.1 2.0 2 0 0 2 2 2 1 PTS HPr component phosphorylation site PEP-utilizers PF00391.23 AIM23652.1 - 9.7e-17 60.5 0.2 9.7e-17 60.5 0.2 2.8 3 0 0 3 3 3 1 PEP-utilising enzyme, mobile domain CortBP2 PF09727.9 AIM23652.1 - 0.091 12.7 0.7 0.28 11.1 0.3 2.0 2 0 0 2 2 2 0 Cortactin-binding protein-2 OmpH PF03938.14 AIM23652.1 - 0.4 11.0 4.9 13 6.1 0.3 3.6 4 0 0 4 4 4 0 Outer membrane protein (OmpH-like) FAA_hydro_N_2 PF18288.1 AIM23652.1 - 5.9 7.4 7.6 0.35 11.3 0.3 2.8 4 0 0 4 4 4 0 Fumarylacetoacetase N-terminal domain 2 Dak2 PF02734.17 AIM23653.1 - 1.7e-57 194.1 2.1 2e-57 193.9 2.1 1.0 1 0 0 1 1 1 1 DAK2 domain YfcL PF08891.11 AIM23653.1 - 0.02 15.2 0.0 0.053 13.9 0.0 1.7 1 1 0 1 1 1 0 YfcL protein Dak1 PF02733.17 AIM23654.1 - 1.8e-123 411.4 0.0 2.1e-123 411.2 0.0 1.0 1 0 0 1 1 1 1 Dak1 domain Fe-ADH PF00465.19 AIM23655.1 - 2e-64 217.7 10.0 2.3e-64 217.5 10.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 AIM23655.1 - 2.1e-32 112.8 2.6 3.1e-32 112.3 2.6 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase PFK PF00365.20 AIM23655.1 - 0.006 15.9 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Phosphofructokinase DUF1190 PF06693.11 AIM23656.1 - 7.9e-59 198.6 11.5 9.8e-59 198.3 11.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1190) NrsF PF06532.11 AIM23656.1 - 0.036 13.8 0.0 0.082 12.6 0.0 1.5 2 0 0 2 2 2 0 Negative regulator of sigma F LPAM_1 PF08139.12 AIM23656.1 - 0.37 11.4 2.9 0.95 10.1 2.9 1.6 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site GSP_synth PF03738.14 AIM23657.1 - 4.3e-165 549.5 0.1 4.9e-165 549.3 0.1 1.0 1 0 0 1 1 1 1 Glutathionylspermidine synthase preATP-grasp LigB PF02900.18 AIM23658.1 - 8e-32 110.4 0.0 9.2e-32 110.2 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Alk_phosphatase PF00245.20 AIM23659.1 - 2.2e-123 412.3 0.2 2.6e-123 412.1 0.2 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 AIM23659.1 - 6.2e-05 22.5 0.1 0.00038 19.9 0.0 2.0 2 0 0 2 2 2 1 Metalloenzyme superfamily Sulfatase PF00884.23 AIM23659.1 - 6.7e-05 22.4 2.1 0.0027 17.2 2.1 2.2 1 1 0 1 1 1 1 Sulfatase DUF229 PF02995.17 AIM23659.1 - 0.23 10.0 0.0 0.52 8.9 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF229) DHBP_synthase PF00926.19 AIM23660.1 - 8.4e-84 279.9 1.3 9.5e-84 279.7 1.3 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase BMFP PF04380.13 AIM23661.1 - 4.9e-29 100.6 5.4 6.2e-29 100.3 5.4 1.1 1 0 0 1 1 1 1 Membrane fusogenic activity ApoC-I PF04691.12 AIM23661.1 - 0.0035 17.2 0.2 0.019 14.9 0.0 2.1 2 0 0 2 2 2 1 Apolipoprotein C-I (ApoC-1) CREPT PF16566.5 AIM23661.1 - 0.027 14.7 2.7 0.03 14.5 2.7 1.1 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour SlyX PF04102.12 AIM23661.1 - 0.97 10.1 6.1 0.26 11.9 1.7 2.2 1 1 1 2 2 2 0 SlyX PfkB PF00294.24 AIM23662.1 - 3.2e-55 187.6 0.2 6e-55 186.7 0.0 1.5 2 0 0 2 2 2 1 pfkB family carbohydrate kinase CTP_transf_like PF01467.26 AIM23662.1 - 5e-15 55.9 0.0 8.6e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like Phos_pyr_kin PF08543.12 AIM23662.1 - 2.8e-06 26.9 0.0 8.1e-06 25.4 0.0 1.7 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase Carb_kinase PF01256.17 AIM23662.1 - 0.00049 19.6 0.1 0.00093 18.7 0.1 1.4 1 0 0 1 1 1 1 Carbohydrate kinase Pantoate_ligase PF02569.15 AIM23662.1 - 0.034 13.4 0.5 0.088 12.0 0.1 1.7 2 0 0 2 2 2 0 Pantoate-beta-alanine ligase FAD_syn PF06574.12 AIM23662.1 - 0.044 13.7 0.0 0.2 11.6 0.0 2.0 2 0 0 2 2 2 0 FAD synthetase DUF4394 PF14339.6 AIM23662.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4394) GlnE PF03710.15 AIM23663.1 - 9.2e-198 654.2 2.8 2.4e-99 331.8 0.3 2.6 2 0 0 2 2 2 2 Glutamate-ammonia ligase adenylyltransferase GlnD_UR_UTase PF08335.11 AIM23663.1 - 1.3e-56 190.8 9.4 3e-46 157.2 0.9 3.1 3 0 0 3 3 3 2 GlnD PII-uridylyltransferase CYTH PF01928.21 AIM23664.1 - 4.4e-32 111.4 0.0 8.5e-32 110.5 0.0 1.5 1 0 0 1 1 1 1 CYTH domain SH3_3 PF08239.11 AIM23665.1 - 3.9e-09 36.7 0.1 6.6e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 Bacterial SH3 domain TPR_MLP1_2 PF07926.12 AIM23665.1 - 0.00017 21.7 3.7 0.00026 21.0 3.7 1.2 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein UPF0242 PF06785.11 AIM23665.1 - 0.00051 20.2 1.7 0.00069 19.8 1.7 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus FlaC_arch PF05377.11 AIM23665.1 - 0.0018 18.6 2.7 0.046 14.1 1.1 2.3 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) Ax_dynein_light PF10211.9 AIM23665.1 - 0.0055 16.7 2.7 0.0081 16.1 2.7 1.2 1 0 0 1 1 1 1 Axonemal dynein light chain DUF4407 PF14362.6 AIM23665.1 - 0.0056 16.1 0.2 0.0081 15.5 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Seryl_tRNA_N PF02403.22 AIM23665.1 - 0.0083 16.4 5.2 0.013 15.7 5.2 1.2 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain HemX PF04375.14 AIM23665.1 - 0.0094 15.3 5.5 0.013 14.9 5.5 1.1 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase GAS PF13851.6 AIM23665.1 - 0.012 14.9 6.0 0.013 14.8 4.5 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF3972 PF13118.6 AIM23665.1 - 0.016 15.7 0.3 0.023 15.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) Spc7 PF08317.11 AIM23665.1 - 0.016 14.1 5.5 0.022 13.7 5.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3584 PF12128.8 AIM23665.1 - 0.019 12.5 3.5 0.023 12.3 3.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Jnk-SapK_ap_N PF09744.9 AIM23665.1 - 0.019 15.2 3.5 0.028 14.6 3.5 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 TMF_DNA_bd PF12329.8 AIM23665.1 - 0.02 14.9 7.0 0.88 9.6 3.8 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Golgin_A5 PF09787.9 AIM23665.1 - 0.02 14.3 1.2 0.025 14.0 1.2 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 ATG16 PF08614.11 AIM23665.1 - 0.024 14.9 4.0 0.033 14.4 4.0 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DivIVA PF05103.13 AIM23665.1 - 0.027 14.6 6.4 0.25 11.4 6.6 1.9 1 1 1 2 2 2 0 DivIVA protein Fmp27_WPPW PF10359.9 AIM23665.1 - 0.03 13.2 2.3 0.04 12.8 2.3 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain GIT_CC PF16559.5 AIM23665.1 - 0.03 14.2 5.3 0.033 14.0 3.9 1.8 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Lebercilin PF15619.6 AIM23665.1 - 0.031 14.0 3.5 0.056 13.1 3.5 1.4 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Prominin PF05478.11 AIM23665.1 - 0.034 12.1 1.5 0.04 11.9 1.5 1.1 1 0 0 1 1 1 0 Prominin CCDC92 PF14916.6 AIM23665.1 - 0.042 13.6 0.5 0.12 12.2 0.1 1.9 2 0 0 2 2 2 0 Coiled-coil domain of unknown function HALZ PF02183.18 AIM23665.1 - 0.046 13.9 1.8 0.87 9.9 0.2 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper FPP PF05911.11 AIM23665.1 - 0.053 11.7 3.7 0.068 11.4 3.7 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Cnn_1N PF07989.11 AIM23665.1 - 0.054 13.6 4.4 0.86 9.8 4.4 2.2 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 Tropomyosin PF00261.20 AIM23665.1 - 0.055 12.8 3.0 0.12 11.7 3.0 1.5 1 1 0 1 1 1 0 Tropomyosin DUF4686 PF15742.5 AIM23665.1 - 0.06 12.5 8.3 0.08 12.1 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) Packaging_FI PF14000.6 AIM23665.1 - 0.076 13.5 0.8 0.12 12.9 0.8 1.2 1 0 0 1 1 1 0 DNA packaging protein FI AAA_13 PF13166.6 AIM23665.1 - 0.11 11.2 3.4 0.14 10.8 3.4 1.1 1 0 0 1 1 1 0 AAA domain DUF1515 PF07439.11 AIM23665.1 - 0.11 12.5 1.2 0.22 11.6 0.7 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF1515) DUF4140 PF13600.6 AIM23665.1 - 0.12 12.8 3.0 8.6 6.9 0.1 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) FlxA PF14282.6 AIM23665.1 - 0.13 12.2 11.6 0.53 10.3 0.7 2.2 1 1 1 2 2 2 0 FlxA-like protein DUF948 PF06103.11 AIM23665.1 - 0.16 12.2 3.5 0.13 12.5 1.6 1.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) TolA_bind_tri PF16331.5 AIM23665.1 - 0.17 12.0 6.7 0.37 10.9 6.7 1.6 1 1 0 1 1 1 0 TolA binding protein trimerisation Apolipoprotein PF01442.18 AIM23665.1 - 0.18 11.7 5.3 0.32 10.8 5.3 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain ZapB PF06005.12 AIM23665.1 - 0.19 12.2 6.8 2.7 8.5 2.4 2.1 1 1 1 2 2 2 0 Cell division protein ZapB ABC_tran_CTD PF16326.5 AIM23665.1 - 0.2 11.9 2.0 1.2 9.5 0.9 2.2 1 1 1 2 2 2 0 ABC transporter C-terminal domain Tropomyosin_1 PF12718.7 AIM23665.1 - 0.23 11.6 7.4 1.1 9.4 7.4 1.8 1 1 0 1 1 1 0 Tropomyosin like Prefoldin_2 PF01920.20 AIM23665.1 - 0.23 11.4 5.6 0.68 9.9 0.2 2.2 1 1 1 2 2 2 0 Prefoldin subunit ADIP PF11559.8 AIM23665.1 - 0.29 11.2 8.0 0.94 9.5 4.2 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Laminin_II PF06009.12 AIM23665.1 - 0.33 11.0 6.1 2.9 7.9 0.2 2.1 1 1 1 2 2 2 0 Laminin Domain II DUF1664 PF07889.12 AIM23665.1 - 0.37 10.8 3.7 0.56 10.2 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) bZIP_1 PF00170.21 AIM23665.1 - 0.44 10.7 3.2 12 6.1 0.1 2.4 1 1 1 2 2 2 0 bZIP transcription factor CLZ PF16526.5 AIM23665.1 - 0.45 10.9 3.7 0.72 10.3 0.3 2.1 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF5320 PF17253.2 AIM23665.1 - 0.5 11.5 1.5 27 5.9 0.5 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5320) DivIC PF04977.15 AIM23665.1 - 0.67 9.8 5.5 3.5 7.5 1.7 2.4 1 1 1 2 2 2 0 Septum formation initiator Swi5 PF07061.11 AIM23665.1 - 0.72 10.0 5.3 7.3 6.8 0.2 2.3 1 1 1 2 2 2 0 Swi5 Fib_alpha PF08702.10 AIM23665.1 - 0.82 9.9 6.4 1.1 9.4 6.4 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family MbeD_MobD PF04899.12 AIM23665.1 - 0.97 9.6 5.1 1.2 9.3 0.1 2.2 1 1 1 2 2 2 0 MbeD/MobD like SlyX PF04102.12 AIM23665.1 - 0.98 10.1 5.9 3.5 8.3 1.9 2.3 1 1 1 2 2 2 0 SlyX YabA PF06156.13 AIM23665.1 - 1.4 9.6 3.9 5.3 7.7 3.9 1.9 1 1 0 1 1 1 0 Initiation control protein YabA PRKG1_interact PF15898.5 AIM23665.1 - 1.4 9.8 6.4 5.8 7.9 6.4 1.8 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain DUF3251 PF11622.8 AIM23665.1 - 2 8.0 6.3 0.93 9.1 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3251) Prefoldin PF02996.17 AIM23665.1 - 2.2 8.2 6.8 1.4 8.9 0.5 2.2 1 1 1 2 2 2 0 Prefoldin subunit Csm1_N PF18504.1 AIM23665.1 - 3.4 8.1 8.6 16 5.9 4.4 2.2 1 1 1 2 2 2 0 Csm1 N-terminal domain PolyA_pol PF01743.20 AIM23666.1 - 2.7e-18 66.6 0.0 1.3e-17 64.4 0.0 2.2 2 1 0 2 2 2 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 AIM23666.1 - 8.5e-17 60.7 0.0 2e-16 59.5 0.0 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A HD PF01966.22 AIM23666.1 - 4.8e-11 42.9 1.1 7.2e-11 42.4 0.1 1.7 2 0 0 2 2 2 1 HD domain BacA PF02673.18 AIM23667.1 - 5.3e-86 288.5 13.6 6.1e-86 288.3 13.6 1.0 1 0 0 1 1 1 1 Bacitracin resistance protein BacA FolB PF02152.18 AIM23668.1 - 1.8e-31 109.0 0.1 2e-31 108.8 0.1 1.0 1 0 0 1 1 1 1 Dihydroneopterin aldolase DUF3141 PF11339.8 AIM23668.1 - 0.066 11.6 0.0 0.079 11.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) G3P_acyltransf PF02660.15 AIM23669.1 - 5.5e-51 172.9 6.8 6.5e-51 172.6 6.8 1.1 1 0 0 1 1 1 1 Glycerol-3-phosphate acyltransferase Peptidase_M22 PF00814.25 AIM23670.1 - 1.2e-104 349.8 0.0 1.4e-104 349.6 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 AIM23670.1 - 2.3e-05 24.2 0.0 0.00034 20.4 0.0 2.0 2 0 0 2 2 2 1 Carbamoyltransferase N-terminus BcrAD_BadFG PF01869.20 AIM23670.1 - 0.0005 19.7 0.0 0.0018 17.8 0.0 1.8 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family TrwC PF08751.11 AIM23670.1 - 0.038 13.5 0.0 0.064 12.8 0.0 1.3 1 1 0 1 1 1 0 TrwC relaxase baeRF_family10 PF18854.1 AIM23670.1 - 0.11 12.8 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 10 Ribosomal_S21 PF01165.20 AIM23671.1 - 6e-22 77.1 6.5 6e-22 77.1 6.5 1.9 1 1 1 2 2 2 1 Ribosomal protein S21 Toprim_N PF08275.11 AIM23672.1 - 1.9e-43 147.6 0.0 3.3e-43 146.8 0.0 1.4 1 0 0 1 1 1 1 DNA primase catalytic core, N-terminal domain zf-CHC2 PF01807.20 AIM23672.1 - 6.6e-41 138.1 0.1 1.5e-40 137.0 0.1 1.6 1 0 0 1 1 1 1 CHC2 zinc finger DnaG_DnaB_bind PF08278.11 AIM23672.1 - 1.5e-34 119.2 3.3 1.5e-34 119.2 3.3 2.0 2 0 0 2 2 2 1 DNA primase DnaG DnaB-binding Toprim_2 PF13155.6 AIM23672.1 - 7.9e-15 55.1 0.0 1.7e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 Toprim-like Toprim_4 PF13662.6 AIM23672.1 - 4.3e-14 52.7 0.0 1e-13 51.5 0.0 1.6 1 0 0 1 1 1 1 Toprim domain DnaB_bind PF10410.9 AIM23672.1 - 1e-12 48.0 0.0 3.2e-12 46.4 0.0 1.9 1 0 0 1 1 1 1 DnaB-helicase binding domain of primase Toprim PF01751.22 AIM23672.1 - 6.8e-11 42.3 0.0 1.4e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Toprim domain Toprim_3 PF13362.6 AIM23672.1 - 4.2e-08 33.5 0.0 7.6e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Toprim domain SANTA PF09133.10 AIM23672.1 - 0.15 12.5 0.0 0.42 11.1 0.0 1.8 1 0 0 1 1 1 0 SANTA (SANT Associated) Sigma70_ner PF04546.13 AIM23673.1 - 4.7e-74 248.7 7.3 4.7e-74 248.7 7.3 2.8 3 0 0 3 3 3 1 Sigma-70, non-essential region Sigma70_r1_1 PF03979.14 AIM23673.1 - 3.4e-30 103.9 5.5 3.4e-30 103.9 5.5 2.9 2 0 0 2 2 2 1 Sigma-70 factor, region 1.1 Sigma70_r3 PF04539.16 AIM23673.1 - 3.8e-29 100.6 1.0 3.8e-29 100.6 1.0 4.7 4 1 1 5 5 5 1 Sigma-70 region 3 Sigma70_r2 PF04542.14 AIM23673.1 - 6.4e-22 77.1 0.3 1.8e-21 75.7 0.3 1.9 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 AIM23673.1 - 1e-18 66.6 0.8 1e-18 66.6 0.8 3.6 3 1 1 4 4 4 1 Sigma-70, region 4 Sigma70_r1_2 PF00140.20 AIM23673.1 - 2.2e-13 49.9 0.3 1.8e-12 47.0 0.1 2.6 2 0 0 2 2 2 1 Sigma-70 factor, region 1.2 DNA_ligase_A_N PF04675.14 AIM23673.1 - 0.0012 19.3 0.8 0.0051 17.1 0.8 2.2 1 0 0 1 1 1 1 DNA ligase N terminus DUF4611 PF15387.6 AIM23673.1 - 0.018 15.3 2.1 0.018 15.3 2.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Sun2_CC2 PF18580.1 AIM23673.1 - 0.082 13.1 4.0 0.51 10.6 0.1 3.0 3 0 0 3 3 2 0 SUN2 coiled coil domain 2 FlgN PF05130.12 AIM23673.1 - 0.16 12.4 0.1 0.16 12.4 0.1 3.6 5 0 0 5 5 4 0 FlgN protein TMPIT PF07851.13 AIM23673.1 - 0.27 10.4 2.4 0.28 10.4 0.6 1.9 2 1 0 2 2 2 0 TMPIT-like protein PAC1 PF16094.5 AIM23673.1 - 0.27 10.3 1.7 0.48 9.5 1.7 1.4 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 BLOC1_2 PF10046.9 AIM23673.1 - 0.5 10.7 3.8 1.5 9.1 0.2 3.4 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HTH_25 PF13413.6 AIM23673.1 - 0.54 10.2 4.1 30 4.6 0.0 3.7 3 0 0 3 3 3 0 Helix-turn-helix domain FAM176 PF14851.6 AIM23673.1 - 4.4 7.0 10.3 15 5.2 4.8 2.5 2 0 0 2 2 2 0 FAM176 family NOA36 PF06524.12 AIM23673.1 - 6.7 5.9 7.8 14 4.9 7.8 1.4 1 0 0 1 1 1 0 NOA36 protein SnoaL PF07366.12 AIM23674.1 - 5.7e-15 55.2 0.3 6.8e-14 51.8 0.3 2.0 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 AIM23674.1 - 3.3e-14 53.4 0.0 4.2e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain UDG PF03167.19 AIM23675.1 - 8.4e-25 87.6 0.0 8.9e-25 87.5 0.0 1.0 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Acetyltransf_1 PF00583.25 AIM23676.1 - 1.7e-14 54.0 0.0 2.1e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 AIM23676.1 - 3.2e-06 27.0 0.0 4.3e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 AIM23676.1 - 1.2e-05 25.0 0.2 4.8e-05 23.1 0.2 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AIM23676.1 - 0.00022 21.9 0.0 0.00027 21.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AIM23676.1 - 0.00053 19.9 0.0 0.00078 19.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AIM23676.1 - 0.0015 18.9 0.0 0.0021 18.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AIM23676.1 - 0.0025 17.9 0.0 0.0029 17.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AIM23676.1 - 0.022 14.8 0.0 0.033 14.3 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AIM23676.1 - 0.08 13.1 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase HPP PF04982.13 AIM23677.1 - 6.5e-40 136.1 10.9 1e-39 135.5 10.9 1.3 1 0 0 1 1 1 1 HPP family GST_C_4 PF14834.6 AIM23678.1 - 8.2e-52 174.5 0.2 1.2e-51 174.0 0.2 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 AIM23678.1 - 2.3e-13 50.4 0.0 5.3e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AIM23678.1 - 6.6e-11 42.4 0.0 1.5e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 AIM23678.1 - 8.2e-11 42.1 0.0 1.6e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain PHM7_cyt PF14703.6 AIM23678.1 - 0.087 13.0 0.0 0.39 10.9 0.0 1.9 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter CLAMP PF14769.6 AIM23678.1 - 0.2 12.1 0.0 0.4 11.2 0.0 1.4 1 0 0 1 1 1 0 Flagellar C1a complex subunit C1a-32 Trp_Tyr_perm PF03222.13 AIM23679.1 - 2.5e-32 112.4 25.6 3.9e-32 111.8 25.6 1.3 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family Aa_trans PF01490.18 AIM23679.1 - 4.5e-10 38.8 27.7 3.7e-08 32.5 27.6 3.0 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Aldedh PF00171.22 AIM23680.1 - 4.1e-172 572.9 5.6 4.5e-172 572.7 5.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aminotran_3 PF00202.21 AIM23681.1 - 3.1e-128 427.9 0.1 3.5e-128 427.7 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 AIM23681.1 - 3.3e-06 26.5 0.0 5.5e-05 22.5 0.0 2.0 2 0 0 2 2 2 2 Aminotransferase class I and II Aminotran_1_2 PF00155.21 AIM23682.1 - 3.4e-24 85.7 0.0 4.4e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II GntR PF00392.21 AIM23682.1 - 6.1e-14 51.4 0.0 1.7e-13 50.0 0.0 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_24 PF13412.6 AIM23682.1 - 0.017 14.7 0.0 0.038 13.6 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF4055 PF13264.6 AIM23682.1 - 0.025 14.7 0.0 0.053 13.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4055) Rrf2 PF02082.20 AIM23682.1 - 0.11 12.9 0.0 0.3 11.5 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator ABC_tran PF00005.27 AIM23683.1 - 1.7e-38 132.3 0.1 3.4e-18 66.5 0.0 3.4 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 AIM23683.1 - 4.3e-20 72.7 3.8 4.6e-05 23.4 0.1 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIM23683.1 - 2e-12 47.0 0.0 0.0075 15.7 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AIM23683.1 - 1.5e-06 28.7 16.6 8.9e-05 22.9 0.3 3.3 2 1 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.23 AIM23683.1 - 1.1e-05 25.5 0.0 0.14 12.2 0.0 3.3 4 0 0 4 4 3 2 50S ribosome-binding GTPase NACHT PF05729.12 AIM23683.1 - 1.4e-05 25.1 0.2 0.026 14.4 0.0 2.6 3 0 0 3 3 2 2 NACHT domain AAA_23 PF13476.6 AIM23683.1 - 2.9e-05 24.7 1.8 0.024 15.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 AIM23683.1 - 4.5e-05 23.1 0.0 0.011 15.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AIM23683.1 - 0.00029 20.8 0.0 0.32 10.9 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 AIM23683.1 - 0.00041 20.6 4.2 0.065 13.5 0.1 3.7 2 2 1 3 3 3 1 AAA domain AAA PF00004.29 AIM23683.1 - 0.00056 20.3 0.2 0.31 11.5 0.1 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 AIM23683.1 - 0.00059 19.1 0.0 0.21 10.7 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain AAA_5 PF07728.14 AIM23683.1 - 0.00084 19.3 0.4 0.67 9.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 AIM23683.1 - 0.0016 18.4 0.3 0.059 13.3 0.1 2.4 2 0 0 2 2 2 1 NTPase AAA_30 PF13604.6 AIM23683.1 - 0.0022 17.7 6.7 0.76 9.5 0.0 3.5 3 1 0 3 3 3 2 AAA domain AAA_15 PF13175.6 AIM23683.1 - 0.0027 17.5 0.0 1.9 8.1 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_24 PF13479.6 AIM23683.1 - 0.003 17.3 0.0 0.33 10.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 AIM23683.1 - 0.0044 17.0 0.0 0.17 11.8 0.0 2.3 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea SbcCD_C PF13558.6 AIM23683.1 - 0.0049 17.1 0.9 1.6 9.0 0.0 3.6 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ABC_tran_Xtn PF12848.7 AIM23683.1 - 0.0056 16.7 10.4 0.13 12.3 10.4 2.5 1 1 0 1 1 1 1 ABC transporter RNA_helicase PF00910.22 AIM23683.1 - 0.0067 16.8 0.1 0.28 11.6 0.0 2.3 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 AIM23683.1 - 0.012 15.7 2.5 0.83 9.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 AIM23683.1 - 0.021 14.8 0.0 0.31 11.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 AIM23683.1 - 0.027 14.0 0.5 1.1 8.8 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 AIM23683.1 - 0.036 13.6 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 AIM23683.1 - 0.087 12.8 0.0 5.5 7.0 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 AIM23683.1 - 0.097 13.0 0.0 8.4 6.7 0.0 2.5 2 1 0 2 2 2 0 AAA domain FeoB_N PF02421.18 AIM23683.1 - 0.12 11.9 0.2 10 5.6 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B Rad17 PF03215.15 AIM23683.1 - 0.12 12.3 0.1 0.33 10.9 0.1 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_28 PF13521.6 AIM23683.1 - 0.19 12.0 0.1 0.19 12.0 0.1 3.8 3 1 0 3 3 2 0 AAA domain Roc PF08477.13 AIM23683.1 - 0.24 11.6 0.1 17 5.6 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase KfrA_N PF11740.8 AIM23683.1 - 0.53 11.0 11.1 1.4 9.6 1.5 2.6 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term AAA_18 PF13238.6 AIM23683.1 - 0.99 10.0 0.0 0.99 10.0 0.0 3.8 5 0 0 5 5 3 0 AAA domain AAA_25 PF13481.6 AIM23683.1 - 2.2 7.8 6.5 3 7.4 0.0 3.5 3 1 0 3 3 3 0 AAA domain DUF3584 PF12128.8 AIM23683.1 - 2.8 5.4 14.1 2 5.8 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) Oxidored_FMN PF00724.20 AIM23684.1 - 1.3e-92 310.7 0.0 1.7e-92 310.3 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.14 AIM23684.1 - 5.4e-26 91.5 0.3 9.7e-26 90.7 0.3 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AIM23684.1 - 8.9e-12 45.1 0.2 4.5e-09 36.4 0.0 2.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 AIM23684.1 - 1.8e-09 38.0 0.9 0.00018 22.0 0.1 3.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AIM23684.1 - 1.4e-07 30.6 1.1 9.5e-07 27.8 0.4 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 AIM23684.1 - 1.4e-07 31.1 0.6 0.0027 17.0 0.0 2.7 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AIM23684.1 - 1.5e-06 28.0 4.7 0.0041 16.8 0.6 3.9 5 1 0 5 5 5 2 FAD dependent oxidoreductase 3HCDH_N PF02737.18 AIM23684.1 - 1.1e-05 25.4 0.1 0.0053 16.7 0.0 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 AIM23684.1 - 1.6e-05 24.3 0.3 0.091 12.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.24 AIM23684.1 - 2e-05 23.9 1.0 5.2e-05 22.5 1.0 1.7 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 AIM23684.1 - 9.2e-05 22.0 0.0 0.00015 21.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 AIM23684.1 - 0.00071 19.2 0.1 0.077 12.6 0.0 2.3 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 AIM23684.1 - 0.00077 18.9 0.0 0.96 8.8 0.0 2.6 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 AIM23684.1 - 0.00085 18.5 0.6 0.0075 15.4 0.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A ThiF PF00899.21 AIM23684.1 - 0.0027 17.1 0.0 0.019 14.3 0.0 2.1 2 0 0 2 2 2 1 ThiF family NAD_Gly3P_dh_N PF01210.23 AIM23684.1 - 0.0028 17.6 0.1 0.074 13.0 0.0 2.4 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_9 PF13454.6 AIM23684.1 - 0.0052 16.8 1.8 0.18 11.8 0.1 3.6 4 0 0 4 4 4 1 FAD-NAD(P)-binding Thi4 PF01946.17 AIM23684.1 - 0.0077 15.5 0.8 0.18 11.0 0.1 2.3 1 1 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.21 AIM23684.1 - 0.012 14.9 2.7 0.013 14.8 0.3 2.1 2 1 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Ldh_1_N PF00056.23 AIM23684.1 - 0.019 15.1 0.1 5.7 7.0 0.0 3.4 4 0 0 4 4 4 0 lactate/malate dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 AIM23684.1 - 0.021 13.9 0.1 0.044 12.8 0.1 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein FMO-like PF00743.19 AIM23684.1 - 0.048 12.1 0.0 0.4 9.1 0.0 2.0 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like F420_oxidored PF03807.17 AIM23684.1 - 0.057 14.0 1.1 11 6.6 0.0 3.0 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 AIM23684.1 - 0.078 13.2 1.9 2.5 8.4 0.1 2.8 3 0 0 3 3 2 0 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 AIM23684.1 - 0.17 11.5 0.5 24 4.6 0.0 2.9 3 0 0 3 3 2 0 Ketopantoate reductase PanE/ApbA MTS PF05175.14 AIM23685.1 - 7e-57 191.6 0.0 5.8e-56 188.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 AIM23685.1 - 1.3e-08 35.5 0.1 3.2e-08 34.1 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AIM23685.1 - 4.8e-08 32.9 0.1 9.2e-08 32.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIM23685.1 - 2.8e-07 31.2 0.1 3.1e-06 27.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 AIM23685.1 - 1.4e-06 28.0 0.0 2.1e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 AIM23685.1 - 1.3e-05 25.0 0.0 3e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 AIM23685.1 - 0.00011 22.8 0.0 0.00023 21.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 AIM23685.1 - 0.00093 19.0 0.1 0.0045 16.8 0.0 2.1 2 0 0 2 2 2 1 Lysine methyltransferase Methyltransf_23 PF13489.6 AIM23685.1 - 0.012 15.4 0.0 0.037 13.9 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 AIM23685.1 - 0.026 14.5 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_10 PF05971.12 AIM23685.1 - 0.061 12.7 0.0 0.091 12.1 0.0 1.4 1 0 0 1 1 1 0 RNA methyltransferase HigB-like_toxin PF05015.13 AIM23686.1 - 7.6e-27 93.6 0.1 8.5e-27 93.4 0.1 1.0 1 0 0 1 1 1 1 RelE-like toxin of type II toxin-antitoxin system HigB HTH_3 PF01381.22 AIM23687.1 - 5.1e-09 36.1 0.0 7.9e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 AIM23687.1 - 3e-06 27.5 0.0 5e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain YdaS_antitoxin PF15943.5 AIM23687.1 - 2.3e-05 24.2 0.0 6.1e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_Crp_2 PF13545.6 AIM23687.1 - 6.6e-05 22.8 0.1 0.00012 21.9 0.1 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_26 PF13443.6 AIM23687.1 - 0.0014 19.0 0.0 0.0032 17.9 0.0 1.6 2 0 0 2 2 1 1 Cro/C1-type HTH DNA-binding domain Crp PF00325.20 AIM23687.1 - 0.0054 16.4 0.1 0.012 15.2 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, crp family LacI PF00356.21 AIM23687.1 - 0.011 15.5 0.0 0.032 14.0 0.0 1.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family HTH_23 PF13384.6 AIM23687.1 - 0.011 15.5 0.2 0.031 14.1 0.0 1.9 2 1 0 2 2 2 0 Homeodomain-like domain HTH_19 PF12844.7 AIM23687.1 - 0.012 15.6 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_17 PF12728.7 AIM23687.1 - 0.017 15.3 0.0 0.04 14.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_6 PF01418.17 AIM23687.1 - 0.037 14.0 0.0 0.054 13.5 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family HTH_24 PF13412.6 AIM23687.1 - 0.041 13.5 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 AIM23687.1 - 0.041 13.7 0.0 0.07 12.9 0.0 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_37 PF13744.6 AIM23687.1 - 0.051 13.5 0.0 0.57 10.2 0.0 2.0 1 1 0 2 2 2 0 Helix-turn-helix domain MarR_2 PF12802.7 AIM23687.1 - 0.075 12.9 0.0 0.19 11.6 0.0 1.8 1 1 0 1 1 1 0 MarR family HTH_11 PF08279.12 AIM23687.1 - 0.087 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 HTH domain Sigma70_r4 PF04545.16 AIM23687.1 - 0.093 12.3 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 DUF45 PF01863.17 AIM23688.1 - 6.2e-11 42.7 1.7 8.2e-11 42.3 0.8 1.3 1 1 0 1 1 1 1 Protein of unknown function DUF45 WLM PF08325.10 AIM23688.1 - 2.1e-05 24.7 0.4 3.6e-05 23.9 0.4 1.4 1 0 0 1 1 1 1 WLM domain Peptidase_M56 PF05569.11 AIM23688.1 - 0.032 13.4 2.0 0.088 12.0 2.0 1.7 1 1 0 1 1 1 0 BlaR1 peptidase M56 GFO_IDH_MocA PF01408.22 AIM23689.1 - 4.1e-26 92.1 0.1 5.9e-26 91.7 0.1 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 AIM23689.1 - 0.012 16.3 0.1 0.02 15.6 0.1 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain GATase PF00117.28 AIM23690.1 - 8.6e-18 64.8 0.0 1.2e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AIM23690.1 - 1.1e-08 35.2 0.3 8.9e-08 32.1 0.1 2.5 2 1 0 2 2 2 1 Peptidase C26 Glyco_trans_4_4 PF13579.6 AIM23690.1 - 1 9.8 4.7 5.4 7.4 4.8 1.9 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain TerC PF03741.16 AIM23691.1 - 2.8e-56 190.1 15.0 2.8e-56 190.1 15.0 2.1 2 0 0 2 2 2 1 Integral membrane protein TerC family MLANA PF14991.6 AIM23691.1 - 0.049 13.9 0.5 1.2 9.5 0.1 2.5 2 0 0 2 2 2 0 Protein melan-A TMEM169 PF15052.6 AIM23691.1 - 2.6 8.2 9.3 0.36 11.0 3.7 2.3 2 1 0 2 2 2 0 TMEM169 protein family SDF PF00375.18 AIM23692.1 - 4.2e-62 210.4 40.9 5.2e-62 210.1 40.9 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF1129 PF06570.11 AIM23692.1 - 2.6 7.5 7.0 9.6 5.6 7.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) GD_AH_C PF04295.13 AIM23693.1 - 5.8e-152 506.0 0.0 2.1e-151 504.2 0.0 1.7 2 0 0 2 2 2 1 D-galactarate dehydratase / Altronate hydrolase, C terminus SAF PF08666.12 AIM23693.1 - 7.7e-15 55.3 0.7 1.5e-14 54.3 0.7 1.5 1 0 0 1 1 1 1 SAF domain UxaC PF02614.14 AIM23694.1 - 4.6e-218 724.7 0.0 5.1e-218 724.5 0.0 1.0 1 0 0 1 1 1 1 Glucuronate isomerase MFS_1 PF07690.16 AIM23695.1 - 8.3e-56 189.4 40.8 5.5e-49 167.0 19.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 AIM23695.1 - 0.21 9.8 15.2 0.0093 14.3 3.7 2.6 1 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Vpu PF00558.19 AIM23695.1 - 0.84 9.5 5.6 7.4 6.4 2.3 2.9 2 1 0 2 2 2 0 Vpu protein GntR PF00392.21 AIM23696.1 - 1.2e-23 82.5 0.5 2.5e-23 81.5 0.2 1.7 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family FCD PF07729.12 AIM23696.1 - 3e-18 66.4 4.6 5.3e-18 65.6 4.6 1.4 1 0 0 1 1 1 1 FCD domain Fe_dep_repress PF01325.19 AIM23696.1 - 0.00057 20.0 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain Rrf2 PF02082.20 AIM23696.1 - 0.00096 19.5 0.1 0.0051 17.1 0.0 2.1 2 0 0 2 2 2 1 Transcriptional regulator HTH_46 PF15977.5 AIM23696.1 - 0.0038 17.2 0.2 0.013 15.4 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA binding HTH_11 PF08279.12 AIM23696.1 - 0.0072 16.2 0.2 0.029 14.3 0.1 2.0 2 0 0 2 2 2 1 HTH domain TrmB PF01978.19 AIM23696.1 - 0.087 12.7 0.2 0.21 11.5 0.2 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB SNARE_assoc PF09335.11 AIM23697.1 - 4.7e-21 75.5 7.1 4.7e-21 75.5 7.1 1.8 2 0 0 2 2 2 1 SNARE associated Golgi protein SecD-TM1 PF13721.6 AIM23698.1 - 1.7e-20 73.4 0.0 2e-20 73.1 0.0 1.0 1 0 0 1 1 1 1 SecD export protein N-terminal TM region DUF1090 PF06476.12 AIM23699.1 - 4e-37 126.7 15.0 4.7e-37 126.5 15.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1090) SMBP PF16785.5 AIM23699.1 - 0.0031 17.7 6.1 0.0035 17.5 6.1 1.1 1 0 0 1 1 1 1 Small metal-binding protein Glyco_hydro_46 PF01374.18 AIM23699.1 - 0.042 13.5 2.5 0.049 13.2 2.5 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 46 RVT_N PF13655.6 AIM23699.1 - 0.094 13.0 5.4 0.61 10.4 0.3 2.2 1 1 1 2 2 2 0 N-terminal domain of reverse transcriptase MCU PF04678.13 AIM23699.1 - 0.75 9.9 5.7 0.9 9.6 5.7 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter TetR_C_21 PF17926.1 AIM23699.1 - 2.2 8.4 8.7 0.67 10.1 4.6 2.1 2 2 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain U1snRNP70_N PF12220.8 AIM23699.1 - 4.6 8.0 11.8 24 5.7 11.8 1.9 1 1 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal EMC3_TMCO1 PF01956.16 AIM23699.1 - 6 6.6 11.7 2.8 7.7 9.3 1.6 1 1 1 2 2 2 0 Integral membrane protein EMC3/TMCO1-like DUF4407 PF14362.6 AIM23699.1 - 6.2 6.1 15.9 7.8 5.8 15.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF883 PF05957.13 AIM23700.1 - 3.5e-31 107.6 1.1 4e-31 107.5 1.1 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 AIM23700.1 - 1.8e-05 25.2 13.1 0.05 14.1 2.1 3.1 3 0 0 3 3 3 2 YtxH-like protein Apolipoprotein PF01442.18 AIM23700.1 - 0.00078 19.4 4.1 0.0011 18.9 4.1 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain CdvA PF18822.1 AIM23700.1 - 0.00091 19.1 1.3 0.0019 18.0 0.6 1.7 1 1 0 1 1 1 1 CdvA-like coiled-coil domain HisKA_3 PF07730.13 AIM23700.1 - 0.0039 17.7 0.6 0.0072 16.8 0.3 1.6 1 1 1 2 2 2 1 Histidine kinase MscS_porin PF12795.7 AIM23700.1 - 0.01 15.4 5.7 0.013 15.1 5.7 1.0 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Remorin_C PF03763.13 AIM23700.1 - 0.011 15.6 1.5 0.012 15.4 1.5 1.1 1 0 0 1 1 1 0 Remorin, C-terminal region DUF543 PF04418.12 AIM23700.1 - 0.016 15.1 0.1 0.022 14.8 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF543) DUF1640 PF07798.11 AIM23700.1 - 0.022 14.8 0.8 0.028 14.5 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) ApoLp-III PF07464.11 AIM23700.1 - 0.027 14.6 0.5 0.047 13.8 0.5 1.3 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) MCU PF04678.13 AIM23700.1 - 0.049 13.7 0.0 0.06 13.4 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF4404 PF14357.6 AIM23700.1 - 0.084 13.5 4.0 0.27 11.9 3.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4404) Acyl-CoA_dh_C PF12806.7 AIM23700.1 - 0.12 12.6 1.2 2.2 8.5 1.3 2.1 1 1 0 1 1 1 0 Acetyl-CoA dehydrogenase C-terminal like DUF4375 PF14300.6 AIM23700.1 - 0.14 12.4 0.1 0.16 12.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4375) Lectin_N PF03954.14 AIM23700.1 - 0.15 11.9 0.4 0.19 11.5 0.4 1.2 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain MukF_M PF17192.4 AIM23700.1 - 0.15 11.8 0.4 0.19 11.4 0.4 1.2 1 0 0 1 1 1 0 MukF middle domain Spc7 PF08317.11 AIM23700.1 - 0.15 10.9 2.5 0.2 10.5 2.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein MbeB_N PF04837.12 AIM23700.1 - 0.47 10.8 3.1 2.8 8.3 3.0 2.0 1 1 0 1 1 1 0 MbeB-like, N-term conserved region Phage_holin_3_6 PF07332.11 AIM23701.1 - 7.9e-18 64.6 11.5 9.5e-18 64.3 11.5 1.0 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III YqjK PF13997.6 AIM23702.1 - 1.7e-30 105.0 4.2 2.2e-30 104.7 4.2 1.1 1 0 0 1 1 1 1 YqjK-like protein DoxX PF07681.12 AIM23703.1 - 1.8e-16 60.5 12.3 1.8e-16 60.5 12.3 1.4 2 0 0 2 2 2 1 DoxX SURF4 PF02077.15 AIM23703.1 - 0.0023 17.6 0.8 0.004 16.8 0.8 1.5 1 1 0 1 1 1 1 SURF4 family DoxD PF04173.13 AIM23703.1 - 0.0035 17.3 0.8 0.006 16.5 0.8 1.4 1 0 0 1 1 1 1 TQO small subunit DoxD DUF1700 PF08006.11 AIM23703.1 - 0.56 9.7 3.3 0.77 9.3 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) GST_N_2 PF13409.6 AIM23704.1 - 4.7e-24 84.5 0.0 8.8e-24 83.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 AIM23704.1 - 5.2e-13 48.8 0.0 1.2e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 AIM23704.1 - 3e-06 27.3 0.0 4.8e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 AIM23704.1 - 4.9e-05 23.4 0.0 8.6e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 AIM23704.1 - 0.00015 22.1 0.0 0.0012 19.2 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 AIM23704.1 - 0.032 14.0 0.0 0.061 13.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain LysR_substrate PF03466.20 AIM23705.1 - 1.9e-17 63.3 1.6 2.9e-17 62.7 1.6 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM23705.1 - 2.4e-16 59.4 0.1 5.4e-16 58.3 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 AIM23705.1 - 0.012 15.5 0.6 0.026 14.4 0.1 1.8 2 0 0 2 2 2 0 MarR family HTH_20 PF12840.7 AIM23705.1 - 0.037 14.1 1.1 0.095 12.8 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain DUF536 PF04394.14 AIM23705.1 - 2.5 8.0 5.7 0.65 9.9 0.5 2.5 3 0 0 3 3 3 0 Protein of unknown function, DUF536 Pirin_C_2 PF17954.1 AIM23706.1 - 5.4e-23 81.0 0.0 1.2e-22 79.9 0.0 1.6 2 0 0 2 2 2 1 Quercetinase C-terminal cupin domain Pirin PF02678.16 AIM23706.1 - 5.9e-22 77.7 0.0 1.6e-21 76.3 0.0 1.7 2 0 0 2 2 2 1 Pirin Cupin_2 PF07883.11 AIM23706.1 - 9.2e-06 25.3 0.0 0.00071 19.2 0.0 2.2 2 0 0 2 2 2 1 Cupin domain Pirin_C PF05726.13 AIM23706.1 - 0.0094 16.3 0.0 1.6 9.2 0.0 2.2 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_3 PF05899.12 AIM23706.1 - 0.04 13.6 0.0 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Amidase02_C PF12123.8 AIM23706.1 - 0.17 11.6 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase TP_methylase PF00590.20 AIM23707.1 - 5.6e-27 95.1 0.1 9.1e-27 94.4 0.1 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases LppC PF04348.13 AIM23708.1 - 2e-142 475.8 22.2 1e-90 305.1 0.3 2.0 2 0 0 2 2 2 2 LppC putative lipoprotein UPF0102 PF02021.17 AIM23709.1 - 5.9e-24 84.1 0.0 6.9e-24 83.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0102 SIS_2 PF13580.6 AIM23710.1 - 2.4e-33 115.1 1.2 2.9e-33 114.8 1.2 1.1 1 0 0 1 1 1 1 SIS domain SIS PF01380.22 AIM23710.1 - 5.1e-07 29.6 0.4 2.2e-05 24.3 0.0 2.6 3 0 0 3 3 3 1 SIS domain HobA PF12163.8 AIM23710.1 - 0.014 15.0 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 DNA replication regulator BON PF04972.17 AIM23711.1 - 1.2e-31 108.8 6.4 2.5e-17 63.0 0.8 2.2 2 0 0 2 2 2 2 BON domain T6SS_Vgr PF13296.6 AIM23711.1 - 0.25 11.5 5.6 12 6.1 0.5 2.9 1 1 2 3 3 3 0 Putative type VI secretion system Rhs element Vgr Peptidase_S10 PF00450.22 AIM23712.1 - 7.1e-20 71.8 0.9 1.2e-19 71.0 0.9 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase DJ-1_PfpI PF01965.24 AIM23713.1 - 2.7e-06 27.3 0.0 1.1e-05 25.2 0.0 1.9 1 1 0 1 1 1 1 DJ-1/PfpI family Catalase_C PF18011.1 AIM23713.1 - 0.075 12.7 0.0 0.31 10.7 0.0 1.9 2 0 0 2 2 2 0 C-terminal domain found in long catalases HATPase_c PF02518.26 AIM23714.1 - 1.8e-30 105.7 0.1 5.3e-30 104.2 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HKR_ArcB_TM PF18415.1 AIM23714.1 - 7.2e-30 103.6 7.1 7.9e-30 103.5 6.0 1.7 1 1 0 1 1 1 1 Histidine kinase receptor ArcB trans-membrane domain Response_reg PF00072.24 AIM23714.1 - 2.1e-22 79.4 0.3 6.9e-22 77.7 0.3 2.0 1 0 0 1 1 1 1 Response regulator receiver domain PAS PF00989.25 AIM23714.1 - 1.3e-18 67.0 0.2 6.9e-18 64.7 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 AIM23714.1 - 3.3e-16 59.5 0.0 8.3e-16 58.2 0.0 1.7 1 0 0 1 1 1 1 PAS fold HisKA PF00512.25 AIM23714.1 - 6.6e-14 51.7 0.2 6.6e-14 51.7 0.2 3.4 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Hpt PF01627.23 AIM23714.1 - 6.8e-13 48.7 0.1 6.8e-13 48.7 0.1 3.5 2 1 0 2 2 1 1 Hpt domain PAS_9 PF13426.7 AIM23714.1 - 2e-06 28.0 0.0 6e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 PAS domain HATPase_c_3 PF13589.6 AIM23714.1 - 0.00033 20.5 0.0 0.00065 19.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Syntaxin_2 PF14523.6 AIM23714.1 - 0.014 15.7 5.7 0.076 13.4 4.9 2.4 2 0 0 2 2 2 0 Syntaxin-like protein PAS_8 PF13188.7 AIM23714.1 - 0.023 14.7 0.0 0.1 12.7 0.0 2.2 1 0 0 1 1 1 0 PAS domain CCB1 PF12046.8 AIM23714.1 - 0.078 12.3 0.2 0.17 11.3 0.2 1.6 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B HATPase_c_2 PF13581.6 AIM23714.1 - 0.1 12.6 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Exonuc_VII_L PF02601.15 AIM23714.1 - 0.17 11.4 5.4 0.056 13.0 2.1 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF3086 PF11285.8 AIM23714.1 - 0.22 10.6 6.6 0.67 9.0 4.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3086) Atg14 PF10186.9 AIM23714.1 - 0.66 9.0 5.8 1.4 8.0 5.8 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 7TMR-HDED PF07697.11 AIM23714.1 - 0.97 9.5 7.0 0.71 10.0 3.6 2.2 2 0 0 2 2 2 0 7TM-HD extracellular FapA PF03961.13 AIM23714.1 - 1.7 7.2 4.9 3 6.3 4.9 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A UPF0242 PF06785.11 AIM23714.1 - 6.5 6.8 12.9 18 5.4 12.9 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Radical_SAM PF04055.21 AIM23715.1 - 1.8e-16 61.0 0.0 2.7e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Radical_SAM_C PF16199.5 AIM23715.1 - 1.2e-14 54.0 0.0 2.4e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain zf-4CXXC_R1 PF10497.9 AIM23715.1 - 0.063 13.5 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 GATase_2 PF00310.21 AIM23716.1 - 1.6e-175 583.9 0.0 2e-175 583.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 AIM23716.1 - 8.2e-157 522.0 0.0 2.2e-156 520.7 0.0 1.7 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 AIM23716.1 - 1.1e-105 353.1 0.0 7.4e-105 350.4 0.0 2.1 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 AIM23716.1 - 6.7e-76 254.1 8.4 1e-75 253.5 7.6 1.7 2 0 0 2 2 2 1 GXGXG motif FMN_dh PF01070.18 AIM23716.1 - 2.6e-06 26.7 0.4 4.1e-05 22.8 0.4 2.2 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Fer4_20 PF14691.6 AIM23717.1 - 2e-38 130.6 0.7 3.1e-38 130.0 0.7 1.2 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.14 AIM23717.1 - 9.3e-30 103.9 7.1 3.3e-24 85.6 3.2 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AIM23717.1 - 3e-12 46.4 0.3 3.1e-06 26.7 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AIM23717.1 - 6.7e-12 45.8 1.5 1.2e-05 25.7 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AIM23717.1 - 7.4e-09 35.7 0.1 1.9e-08 34.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 AIM23717.1 - 2e-06 27.3 0.2 4.1e-06 26.3 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 AIM23717.1 - 2.2e-06 27.1 0.0 4.7e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_7 PF13241.6 AIM23717.1 - 3.1e-06 27.6 1.0 0.1 13.1 0.2 2.9 2 1 0 2 2 2 2 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 AIM23717.1 - 2e-05 24.0 0.1 0.0006 19.2 0.0 2.6 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 AIM23717.1 - 2e-05 23.8 2.0 0.0049 16.0 0.4 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 AIM23717.1 - 2.3e-05 23.9 0.1 4.1e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FMO-like PF00743.19 AIM23717.1 - 4.5e-05 22.1 0.0 0.008 14.7 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like HI0933_like PF03486.14 AIM23717.1 - 7.5e-05 21.6 0.1 0.00015 20.6 0.1 1.5 1 0 0 1 1 1 1 HI0933-like protein Shikimate_DH PF01488.20 AIM23717.1 - 0.00019 21.5 0.0 1.3 9.1 0.0 2.8 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 AIM23717.1 - 0.00073 19.2 2.4 0.0065 16.1 0.8 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase F420_oxidored PF03807.17 AIM23717.1 - 0.0046 17.5 0.2 13 6.5 0.0 3.9 4 1 1 5 5 5 0 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 AIM23717.1 - 0.0047 16.3 2.6 0.79 9.0 0.1 2.8 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 AIM23717.1 - 0.0082 16.1 1.0 0.21 11.6 0.2 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 AIM23717.1 - 0.0092 15.2 0.0 1.3 8.1 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 AIM23717.1 - 0.042 13.1 0.2 0.2 10.9 0.0 2.1 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase XdhC_C PF13478.6 AIM23717.1 - 0.056 13.9 0.4 2.1 8.8 0.0 2.5 2 1 0 2 2 2 0 XdhC Rossmann domain Oxidored_nitro PF00148.19 AIM23717.1 - 0.059 12.1 0.1 5.2 5.7 0.0 2.3 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase Fer4_7 PF12838.7 AIM23717.1 - 0.071 13.7 3.6 0.11 13.1 0.2 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain IlvN PF07991.12 AIM23717.1 - 0.08 12.5 0.0 1.1 8.8 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 AIM23717.1 - 0.085 12.7 0.1 0.19 11.6 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 AIM23717.1 - 0.092 12.7 0.0 0.18 11.8 0.0 1.6 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ELFV_dehydrog PF00208.21 AIM23717.1 - 0.1 12.3 0.1 6.5 6.4 0.0 2.3 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AdoHcyase_NAD PF00670.21 AIM23717.1 - 0.11 12.5 1.2 8.9 6.4 0.1 2.4 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Fer4_17 PF13534.6 AIM23717.1 - 9.6 6.8 9.4 0.75 10.4 1.4 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain SspB PF04386.13 AIM23719.1 - 1.3e-41 142.2 0.0 1.5e-41 142.0 0.0 1.0 1 0 0 1 1 1 1 Stringent starvation protein B GST_N PF02798.20 AIM23720.1 - 1e-21 77.0 0.0 1.7e-18 66.7 0.0 2.2 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 AIM23720.1 - 1.4e-16 60.7 0.0 1e-15 57.9 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AIM23720.1 - 1.7e-12 47.4 0.0 4e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 AIM23720.1 - 4.7e-12 46.0 0.0 6.9e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 AIM23720.1 - 8.5e-07 28.9 0.0 1.5e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 AIM23720.1 - 0.00046 20.3 0.0 0.00095 19.3 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_C_5 PF16865.5 AIM23720.1 - 0.044 14.4 0.0 0.25 11.9 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Ribosomal_S9 PF00380.19 AIM23721.1 - 5.9e-47 159.1 1.1 6.6e-47 159.0 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Flg_hook PF02120.16 AIM23721.1 - 0.0098 15.8 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Flagellar hook-length control protein FliK Ribosomal_L13 PF00572.18 AIM23722.1 - 8.4e-57 190.8 0.2 9.6e-57 190.6 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 DUF3659 PF12396.8 AIM23722.1 - 0.074 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) AFG1_ATPase PF03969.16 AIM23723.1 - 1.2e-148 494.9 0.1 1.3e-148 494.7 0.1 1.0 1 0 0 1 1 1 1 AFG1-like ATPase DUF1043 PF06295.12 AIM23724.1 - 1.8e-48 163.6 0.0 2e-48 163.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1043) HemX PF04375.14 AIM23724.1 - 0.0025 17.2 0.1 0.003 16.9 0.1 1.1 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase KAP PF05804.12 AIM23724.1 - 0.016 13.4 0.0 0.018 13.2 0.0 1.0 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) MctB PF11382.8 AIM23724.1 - 0.041 13.6 0.2 0.06 13.0 0.2 1.2 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB DUF883 PF05957.13 AIM23724.1 - 0.17 12.5 4.4 0.2 12.3 0.1 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF4514 PF14986.6 AIM23724.1 - 0.19 11.7 0.5 0.37 10.8 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4514) AAA_9 PF12781.7 AIM23724.1 - 0.19 10.8 0.9 0.24 10.5 0.9 1.1 1 0 0 1 1 1 0 ATP-binding dynein motor region 7tm_7 PF08395.12 AIM23724.1 - 0.27 10.4 0.3 0.33 10.1 0.3 1.0 1 0 0 1 1 1 0 7tm Chemosensory receptor Trypsin_2 PF13365.6 AIM23725.1 - 1.1e-31 110.8 0.2 1.9e-31 110.0 0.2 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ PF00595.24 AIM23725.1 - 2.6e-28 98.2 3.9 8.5e-15 54.9 0.0 3.3 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 AIM23725.1 - 1.1e-25 89.7 5.4 2.2e-16 60.0 0.0 3.2 3 0 0 3 3 3 2 PDZ domain PDZ_6 PF17820.1 AIM23725.1 - 4.7e-22 77.6 1.2 4.1e-11 42.6 0.0 2.7 2 0 0 2 2 2 2 PDZ domain Trypsin PF00089.26 AIM23725.1 - 3.3e-17 63.0 0.0 6.4e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.6 AIM23725.1 - 1.8e-05 24.6 0.7 0.17 11.9 0.0 3.2 2 0 0 2 2 2 2 Tricorn protease PDZ domain PDZ_1 PF12812.7 AIM23725.1 - 0.00055 19.9 0.1 0.85 9.7 0.0 3.0 2 1 0 2 2 2 2 PDZ-like domain DUF3394 PF11874.8 AIM23725.1 - 0.011 15.4 0.1 0.063 13.0 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3394) Peptidase_S46 PF10459.9 AIM23725.1 - 0.036 12.7 0.8 0.31 9.6 0.8 2.0 2 0 0 2 2 2 0 Peptidase S46 Trypsin_2 PF13365.6 AIM23726.1 - 1.5e-30 107.1 0.6 2.1e-30 106.6 0.6 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 AIM23726.1 - 6.1e-17 62.2 0.2 1.6e-16 60.8 0.2 1.6 1 1 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 AIM23726.1 - 4.1e-13 49.5 0.4 2e-12 47.3 0.1 2.2 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 AIM23726.1 - 1.5e-10 41.3 1.5 1.4e-09 38.2 0.6 2.4 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 AIM23726.1 - 4.8e-07 29.5 0.8 2.5e-06 27.2 0.1 2.3 2 0 0 2 2 2 1 PDZ domain Peptidase_S46 PF10459.9 AIM23726.1 - 0.0042 15.8 0.6 0.14 10.8 0.3 2.0 2 0 0 2 2 2 1 Peptidase S46 LSM PF01423.22 AIM23726.1 - 0.071 12.8 0.0 0.26 11.0 0.0 1.9 1 0 0 1 1 1 0 LSM domain EPSP_synthase PF00275.20 AIM23727.1 - 4.1e-127 424.3 0.7 4.7e-127 424.1 0.7 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) BolA PF01722.18 AIM23728.1 - 1.7e-15 57.0 0.0 2.1e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein DUF3206 PF11472.8 AIM23728.1 - 0.0037 17.3 0.0 0.0039 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3206) GP70 PF17429.2 AIM23728.1 - 0.15 11.9 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Gene product 70 STAS_2 PF13466.6 AIM23729.1 - 6.2e-17 61.7 3.0 7.5e-17 61.5 3.0 1.1 1 0 0 1 1 1 1 STAS domain STAS PF01740.21 AIM23729.1 - 1e-05 25.1 0.0 1e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 STAS domain MlaC PF05494.12 AIM23730.1 - 1.6e-53 180.9 0.3 1.8e-53 180.7 0.3 1.0 1 0 0 1 1 1 1 MlaC protein MlaD PF02470.20 AIM23731.1 - 1.5e-21 76.5 0.0 2e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 MlaD protein MlaE PF02405.16 AIM23732.1 - 6.8e-76 254.6 15.7 1e-75 254.0 15.7 1.3 1 0 0 1 1 1 1 Permease MlaE ABC_tran PF00005.27 AIM23733.1 - 2.2e-29 102.7 0.0 3.3e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIM23733.1 - 5e-08 33.1 0.1 0.003 17.4 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 AIM23733.1 - 0.00023 21.1 0.0 0.00037 20.4 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 AIM23733.1 - 0.00023 21.6 0.0 0.00037 20.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 AIM23733.1 - 0.00038 20.1 0.0 0.011 15.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 AIM23733.1 - 0.0016 18.7 0.0 0.0032 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain BCA_ABC_TP_C PF12399.8 AIM23733.1 - 0.0017 18.2 0.1 0.004 17.0 0.1 1.7 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_23 PF13476.6 AIM23733.1 - 0.003 18.1 0.1 0.0042 17.6 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AIM23733.1 - 0.011 15.5 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_3 PF07726.11 AIM23733.1 - 0.011 15.5 0.0 0.027 14.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 AIM23733.1 - 0.012 14.5 4.7 1 8.1 0.9 2.4 2 1 0 2 2 2 0 Predicted ATPase of the ABC class AAA_24 PF13479.6 AIM23733.1 - 0.029 14.1 0.1 0.048 13.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 AIM23733.1 - 0.03 14.4 0.0 0.056 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 AIM23733.1 - 0.094 13.1 0.0 0.33 11.4 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 AIM23733.1 - 0.1 12.9 0.3 1.2 9.4 0.2 2.6 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 AIM23733.1 - 0.15 11.9 0.2 0.27 11.1 0.2 1.4 1 0 0 1 1 1 0 NACHT domain Na_Ca_ex PF01699.24 AIM23734.1 - 3e-58 196.1 36.2 2.2e-29 102.4 14.3 2.0 2 0 0 2 2 2 2 Sodium/calcium exchanger protein COX7a PF02238.15 AIM23734.1 - 0.57 10.6 2.0 49 4.4 1.1 3.3 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VII SIS PF01380.22 AIM23735.1 - 1.6e-31 108.9 0.2 2.6e-31 108.2 0.2 1.4 1 0 0 1 1 1 1 SIS domain CBS PF00571.28 AIM23735.1 - 1.2e-13 51.2 4.6 1.5e-05 25.3 0.1 3.3 3 0 0 3 3 3 2 CBS domain DUF2529 PF10740.9 AIM23735.1 - 0.0047 16.6 0.0 0.0074 15.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2529) SIS_2 PF13580.6 AIM23735.1 - 0.07 13.1 1.4 1.1 9.3 0.1 2.3 1 1 1 2 2 2 0 SIS domain Hydrolase_3 PF08282.12 AIM23736.1 - 5.9e-12 45.9 0.0 5.6e-09 36.1 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AIM23736.1 - 0.00057 20.2 0.0 0.0047 17.2 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 AIM23736.1 - 0.0029 17.7 1.0 0.017 15.2 0.1 2.3 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase S6PP PF05116.13 AIM23736.1 - 0.12 11.9 0.0 1.8 8.0 0.0 2.0 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Hydrolase_6 PF13344.6 AIM23736.1 - 0.16 12.1 0.1 0.35 11.0 0.1 1.5 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase LptC PF06835.13 AIM23737.1 - 7.1e-54 182.0 3.7 8.7e-54 181.7 3.7 1.0 1 0 0 1 1 1 1 Lipopolysaccharide-assembly, LptC-related ABC2_membrane_3 PF12698.7 AIM23737.1 - 0.1 11.7 0.4 0.13 11.4 0.4 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein OstA PF03968.14 AIM23738.1 - 6.1e-30 103.7 2.6 8e-30 103.4 2.6 1.1 1 0 0 1 1 1 1 OstA-like protein OstA_2 PF13100.6 AIM23738.1 - 2.2e-05 24.1 1.2 3e-05 23.7 1.2 1.1 1 0 0 1 1 1 1 OstA-like protein LptC PF06835.13 AIM23738.1 - 0.0019 17.8 1.5 0.01 15.4 1.5 2.0 1 1 0 1 1 1 1 Lipopolysaccharide-assembly, LptC-related Band_7_C PF16200.5 AIM23738.1 - 0.06 13.4 0.1 1.6 8.9 0.0 2.6 3 0 0 3 3 3 0 C-terminal region of band_7 PUB_1 PF18486.1 AIM23738.1 - 0.38 10.6 1.3 18 5.3 0.3 2.5 1 1 1 2 2 2 0 PNGase/UBA- or UBX-containing domain ABC_tran PF00005.27 AIM23739.1 - 6.9e-34 117.3 0.0 1.1e-33 116.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter BCA_ABC_TP_C PF12399.8 AIM23739.1 - 8.6e-09 35.1 0.0 1.8e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_21 PF13304.6 AIM23739.1 - 0.0022 17.9 2.9 0.4 10.4 0.2 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 AIM23739.1 - 0.0028 16.8 0.0 0.0037 16.4 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein SMC_N PF02463.19 AIM23739.1 - 0.0059 16.1 0.1 3.3 7.1 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AIM23739.1 - 0.069 13.6 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 AIM23739.1 - 0.1 12.9 0.1 0.92 9.8 0.1 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Sigma54_DBD PF04552.13 AIM23740.1 - 4.9e-70 234.4 0.5 9.4e-70 233.4 0.3 1.6 2 0 0 2 2 2 1 Sigma-54, DNA binding domain Sigma54_CBD PF04963.13 AIM23740.1 - 1.5e-61 207.4 0.3 1.5e-61 207.4 0.3 1.7 2 0 0 2 2 2 1 Sigma-54 factor, core binding domain Sigma54_AID PF00309.20 AIM23740.1 - 1.2e-15 57.1 19.4 3.7e-15 55.5 19.4 1.9 1 0 0 1 1 1 1 Sigma-54 factor, Activator interacting domain (AID) Ribosomal_S30AE PF02482.19 AIM23741.1 - 9.2e-29 100.1 1.2 1e-28 99.9 1.2 1.0 1 0 0 1 1 1 1 Sigma 54 modulation protein / S30EA ribosomal protein HJURP_C PF12347.8 AIM23741.1 - 0.031 14.3 0.1 6.7 6.8 0.0 2.1 1 1 1 2 2 2 0 Holliday junction regulator protein family C-terminal repeat Baculo_PEP_C PF04513.12 AIM23741.1 - 0.04 13.9 0.2 0.26 11.3 0.2 2.0 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus PTS_EIIA_2 PF00359.22 AIM23742.1 - 8.3e-37 126.3 0.0 9.3e-37 126.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 ATP_bind_2 PF03668.15 AIM23743.1 - 1.3e-144 480.8 0.0 1.4e-144 480.6 0.0 1.0 1 0 0 1 1 1 1 P-loop ATPase protein family AAA_18 PF13238.6 AIM23743.1 - 0.021 15.4 0.0 0.83 10.2 0.0 2.9 2 1 0 2 2 2 0 AAA domain CPT PF07931.12 AIM23743.1 - 0.08 12.8 0.0 2 8.2 0.0 2.1 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_16 PF13191.6 AIM23743.1 - 0.081 13.3 0.1 0.19 12.1 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 AIM23743.1 - 0.098 12.8 0.0 0.34 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AIM23743.1 - 0.12 12.7 0.1 0.35 11.1 0.1 2.1 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 AIM23743.1 - 0.13 11.6 0.2 0.13 11.6 0.2 1.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family PTS-HPr PF00381.19 AIM23744.1 - 6.7e-23 80.7 0.6 7.3e-23 80.6 0.6 1.0 1 0 0 1 1 1 1 PTS HPr component phosphorylation site HigB_toxin PF09907.9 AIM23745.1 - 4.3e-22 78.1 0.0 5.3e-22 77.8 0.0 1.1 1 0 0 1 1 1 1 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system DUF4296 PF14129.6 AIM23745.1 - 0.01 16.5 0.3 0.8 10.4 0.4 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4296) HTH_3 PF01381.22 AIM23746.1 - 4.1e-09 36.4 0.0 1.4e-07 31.5 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix HTH_26 PF13443.6 AIM23746.1 - 0.0015 18.9 0.0 0.0023 18.3 0.0 1.3 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain TPR_16 PF13432.6 AIM23746.1 - 0.0076 16.9 0.4 0.9 10.2 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat Lactonase PF10282.9 AIM23747.1 - 3.2e-104 348.9 0.0 3.7e-104 348.7 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SGL PF08450.12 AIM23747.1 - 1.9e-08 34.2 0.0 0.00055 19.6 0.0 4.6 1 1 3 5 5 5 3 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 AIM23747.1 - 0.00012 22.0 0.1 0.34 11.0 0.0 4.5 4 0 0 4 4 4 1 NHL repeat DUF1513 PF07433.11 AIM23747.1 - 0.003 16.7 0.2 0.25 10.4 0.1 2.9 2 1 1 3 3 3 1 Protein of unknown function (DUF1513) Arylesterase PF01731.20 AIM23747.1 - 0.06 13.5 0.0 2.7 8.3 0.0 3.2 4 0 0 4 4 4 0 Arylesterase Phytase-like PF13449.6 AIM23747.1 - 0.082 12.8 0.0 1.2 9.0 0.0 2.9 3 1 0 3 3 3 0 Esterase-like activity of phytase PD40 PF07676.12 AIM23747.1 - 0.084 12.8 0.0 11 6.1 0.0 4.1 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat KDGP_aldolase PF07071.11 AIM23748.1 - 3e-107 357.3 0.2 3.5e-107 357.1 0.2 1.0 1 0 0 1 1 1 1 KDGP aldolase Arabinose_bd PF12625.7 AIM23748.1 - 0.0033 17.5 0.0 0.0058 16.7 0.0 1.4 1 0 0 1 1 1 1 Arabinose-binding domain of AraC transcription regulator, N-term SelA PF03841.13 AIM23749.1 - 2.3e-15 56.5 1.5 2.3e-14 53.2 1.5 2.1 1 1 0 1 1 1 1 L-seryl-tRNA selenium transferase Cys_Met_Meta_PP PF01053.20 AIM23749.1 - 1.2e-07 30.6 0.6 4.1e-07 28.9 0.0 1.8 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 AIM23749.1 - 0.00028 20.3 3.7 0.00057 19.3 3.7 1.6 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 AIM23749.1 - 0.002 17.4 0.4 0.0047 16.3 0.4 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Amidohydro_1 PF01979.20 AIM23750.1 - 4.8e-10 39.3 0.2 1.4e-08 34.5 0.2 2.6 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AIM23750.1 - 3.4e-08 33.4 0.2 6.7e-07 29.1 0.0 2.3 2 1 0 2 2 2 1 Amidohydrolase family DUF4310 PF14187.6 AIM23751.1 - 6.3e-106 352.7 28.2 7.4e-106 352.5 28.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4310) DUF4311 PF14188.6 AIM23752.1 - 1.2e-121 404.3 11.0 1.5e-121 404.0 11.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4311) DUF2232 PF09991.9 AIM23752.1 - 0.056 12.6 11.6 0.013 14.7 7.1 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2232) DUF4312 PF14189.6 AIM23753.1 - 5.7e-37 125.6 0.8 6.7e-37 125.4 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4312) Gly_rich_SFCGS PF14272.6 AIM23754.1 - 4.2e-62 207.2 8.2 4.7e-62 207.0 8.2 1.0 1 0 0 1 1 1 1 Glycine-rich SFCGS LacAB_rpiB PF02502.18 AIM23754.1 - 0.0091 16.0 0.4 0.011 15.7 0.4 1.2 1 0 0 1 1 1 1 Ribose/Galactose Isomerase DUF1685 PF07939.11 AIM23754.1 - 0.11 12.3 0.1 0.18 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1685) PRD PF00874.20 AIM23755.1 - 0.0038 17.5 0.1 0.0053 17.0 0.1 1.3 1 0 0 1 1 1 1 PRD domain GreA_GreB PF01272.19 AIM23756.1 - 6.5e-18 64.4 0.0 8.7e-18 64.0 0.0 1.2 1 0 0 1 1 1 1 Transcription elongation factor, GreA/GreB, C-term Rnk_N PF14760.6 AIM23756.1 - 7.7e-13 48.7 4.2 1.4e-12 47.9 4.2 1.4 1 0 0 1 1 1 1 Rnk N-terminus TauE PF01925.19 AIM23757.1 - 4.6e-35 121.4 34.9 5.7e-35 121.1 34.9 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE B12D PF06522.11 AIM23757.1 - 1.2 9.0 3.4 1.4 8.8 0.4 2.8 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Formyl_trans_N PF00551.19 AIM23758.1 - 6.5e-09 35.8 0.0 9.6e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase FrhB_FdhB_N PF04422.13 AIM23758.1 - 0.19 11.9 0.0 0.4 10.8 0.0 1.5 1 0 0 1 1 1 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term NAD_binding_9 PF13454.6 AIM23759.1 - 9.3e-26 90.7 0.0 1.5e-25 90.0 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 AIM23759.1 - 7e-05 23.0 0.0 0.00016 21.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 AIM23759.1 - 0.029 13.6 0.0 0.65 9.2 0.1 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AIM23759.1 - 0.037 13.6 0.0 0.64 9.5 0.0 2.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase HTH_18 PF12833.7 AIM23760.1 - 3.1e-19 69.0 0.8 7.4e-19 67.8 0.8 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AIM23760.1 - 2.1e-11 43.6 2.2 7.7e-07 29.1 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family AraC_binding PF02311.19 AIM23760.1 - 3.3e-09 36.8 0.1 5.8e-09 36.0 0.1 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_2 PF07883.11 AIM23760.1 - 0.00027 20.6 0.1 0.00043 19.9 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cytochrom_B562 PF07361.11 AIM23761.1 - 6.9e-32 110.1 3.8 1e-31 109.6 3.8 1.2 1 0 0 1 1 1 1 Cytochrome b562 4HB_MCP_1 PF12729.7 AIM23761.1 - 0.008 15.7 1.5 0.021 14.4 1.5 1.7 1 1 0 1 1 1 1 Four helix bundle sensory module for signal transduction DUF3220 PF11516.8 AIM23761.1 - 0.04 14.1 0.4 0.058 13.6 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3120) DUF4972 PF16342.5 AIM23761.1 - 0.09 12.5 0.3 0.12 12.0 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4972) TrbC PF04956.13 AIM23761.1 - 0.27 11.5 1.8 0.32 11.3 0.7 1.7 2 0 0 2 2 2 0 TrbC/VIRB2 family PmbA_TldD PF01523.16 AIM23762.1 - 7e-61 206.5 0.2 2.6e-60 204.7 0.0 1.8 1 1 1 2 2 2 1 Putative modulator of DNA gyrase HTH_37 PF13744.6 AIM23763.1 - 4.2e-18 65.1 1.2 1.4e-16 60.2 1.2 2.0 1 1 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 AIM23763.1 - 0.0016 18.1 0.1 0.34 10.6 0.0 2.2 2 0 0 2 2 2 2 Sigma-70, region 4 NDK PF00334.19 AIM23763.1 - 0.0021 18.1 0.1 0.0027 17.7 0.1 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase HTH_3 PF01381.22 AIM23763.1 - 0.0038 17.3 0.0 0.0069 16.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_23 PF13384.6 AIM23763.1 - 0.012 15.4 0.3 0.034 14.0 0.2 1.8 1 1 1 2 2 2 0 Homeodomain-like domain HTH_31 PF13560.6 AIM23763.1 - 0.056 13.8 0.1 0.091 13.1 0.1 1.5 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_17 PF12728.7 AIM23763.1 - 0.12 12.6 0.1 0.28 11.4 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain MarR_2 PF12802.7 AIM23763.1 - 0.13 12.1 0.1 0.26 11.2 0.1 1.7 1 1 0 1 1 1 0 MarR family Gp49 PF05973.14 AIM23764.1 - 2.3e-21 75.7 0.0 2.7e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 Phage derived protein Gp49-like (DUF891) Somatostatin PF03002.15 AIM23764.1 - 0.33 10.9 1.0 0.57 10.2 1.0 1.4 1 0 0 1 1 1 0 Somatostatin/Cortistatin family DUF615 PF04751.14 AIM23765.1 - 1.4e-56 190.7 7.3 1.7e-56 190.5 7.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF615) GvpL_GvpF PF06386.11 AIM23765.1 - 1.8 8.4 5.8 1.2 9.1 1.8 2.0 1 1 1 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF Barstar PF01337.18 AIM23766.1 - 8.7e-11 41.7 0.1 1.1e-10 41.4 0.1 1.1 1 0 0 1 1 1 1 Barstar (barnase inhibitor) Ribonuclease PF00545.20 AIM23767.1 - 4.5e-24 85.0 0.0 6.4e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 ribonuclease FUSC PF04632.12 AIM23768.1 - 3.4e-135 452.2 26.2 3.8e-135 452.0 26.2 1.0 1 0 0 1 1 1 1 Fusaric acid resistance protein family FUSC_2 PF13515.6 AIM23768.1 - 3.2e-12 46.7 15.4 3.2e-12 46.7 15.4 3.2 2 1 1 3 3 3 1 Fusaric acid resistance protein-like DUF1427 PF07235.11 AIM23768.1 - 0.16 12.0 0.6 0.73 9.8 0.6 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1427) ALMT PF11744.8 AIM23768.1 - 0.31 9.8 2.9 0.45 9.3 2.4 1.5 1 1 0 1 1 1 0 Aluminium activated malate transporter Biotin_lipoyl_2 PF13533.6 AIM23769.1 - 1.8e-18 66.1 2.9 5.2e-15 55.0 1.8 2.8 2 0 0 2 2 2 2 Biotin-lipoyl like HlyD_D23 PF16576.5 AIM23769.1 - 1.7e-15 56.8 2.1 4e-15 55.6 2.1 1.5 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AIM23769.1 - 4.6e-13 49.8 1.2 2.6e-09 37.7 0.0 2.7 2 1 0 2 2 2 2 HlyD family secretion protein HlyD PF00529.20 AIM23769.1 - 2.6e-05 24.0 0.0 5.8e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS ChapFlgA PF13144.6 AIM23769.1 - 0.0033 17.5 1.4 0.0038 17.3 0.2 1.7 2 0 0 2 2 2 1 Chaperone for flagella basal body P-ring formation Phage_DNA_bind PF02303.17 AIM23769.1 - 0.021 15.1 0.0 0.04 14.2 0.0 1.4 1 0 0 1 1 1 0 Helix-destabilising protein DUF3880 PF12996.7 AIM23769.1 - 0.03 14.4 0.0 0.091 12.8 0.0 1.8 1 1 0 1 1 1 0 DUF based on E. rectale Gene description (DUF3880) Biotin_lipoyl PF00364.22 AIM23769.1 - 0.045 13.6 0.1 11 5.9 0.0 2.7 2 1 0 2 2 2 0 Biotin-requiring enzyme DUF1656 PF07869.12 AIM23770.1 - 2e-20 72.6 9.5 2.4e-20 72.3 9.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1656) LysR_substrate PF03466.20 AIM23771.1 - 7.7e-38 130.0 0.0 9.7e-38 129.6 0.0 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM23771.1 - 7.5e-20 70.6 0.3 1.4e-19 69.8 0.3 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family GST_N_4 PF17172.4 AIM23771.1 - 0.11 13.3 0.0 0.28 11.9 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain P22_Cro PF14549.6 AIM23771.1 - 0.17 11.7 0.0 0.95 9.4 0.0 2.1 2 0 0 2 2 2 0 DNA-binding transcriptional regulator Cro DZR PF12773.7 AIM23773.1 - 1.7e-10 40.7 14.8 2.3e-10 40.3 14.8 1.2 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 AIM23773.1 - 1.7e-08 33.9 17.1 0.00018 21.1 4.6 2.2 2 0 0 2 2 2 2 zinc-ribbon domain zinc_ribbon_15 PF17032.5 AIM23773.1 - 1.1e-06 29.3 8.2 0.0085 16.8 0.6 2.1 2 0 0 2 2 2 2 zinc-ribbon family zf-ribbon_3 PF13248.6 AIM23773.1 - 0.0019 17.5 17.9 0.0048 16.3 5.8 2.2 2 0 0 2 2 2 2 zinc-ribbon domain Cript PF10235.9 AIM23773.1 - 0.01 16.4 8.1 0.25 11.9 3.0 2.1 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT TerY_C PF15616.6 AIM23773.1 - 0.023 14.8 6.1 0.027 14.6 6.1 1.1 1 0 0 1 1 1 0 TerY-C metal binding domain zf-RanBP PF00641.18 AIM23773.1 - 0.036 13.4 1.3 0.036 13.4 1.3 2.6 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others zf-TRM13_CCCH PF11722.8 AIM23773.1 - 0.051 13.4 2.5 1.3 8.8 0.0 2.6 2 0 0 2 2 2 0 CCCH zinc finger in TRM13 protein DHHC PF01529.20 AIM23773.1 - 0.056 13.6 6.1 1.2 9.2 2.2 2.1 1 1 1 2 2 2 0 DHHC palmitoyltransferase zf-P11 PF03854.14 AIM23773.1 - 0.14 11.9 3.2 0.078 12.7 1.1 1.8 1 1 0 1 1 1 0 P-11 zinc finger Nudix_N_2 PF14803.6 AIM23773.1 - 0.25 11.3 1.0 0.25 11.3 1.0 4.0 4 0 0 4 4 4 0 Nudix N-terminal zf-NADH-PPase PF09297.11 AIM23773.1 - 1.3 8.7 26.1 0.36 10.5 2.6 4.2 4 0 0 4 4 4 0 NADH pyrophosphatase zinc ribbon domain zf-C3HC4_3 PF13920.6 AIM23773.1 - 2.4 8.1 9.5 2.1e+02 1.9 9.5 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) NOB1_Zn_bind PF08772.11 AIM23773.1 - 3.4 7.9 12.7 5.8 7.2 2.1 2.4 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like IU_nuc_hydro PF01156.19 AIM23774.1 - 6e-06 26.0 0.4 6e-06 26.0 0.4 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase IU_nuc_hydro PF01156.19 AIM23775.1 - 1.1e-94 317.4 0.3 1.3e-94 317.2 0.3 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Wzy_C_2 PF11846.8 AIM23776.1 - 2.7e-19 69.8 8.0 2.7e-19 69.8 8.0 3.6 3 1 1 4 4 4 1 Virulence factor membrane-bound polymerase, C-terminal Wzy_C PF04932.15 AIM23776.1 - 1.9e-15 56.8 6.9 1.9e-15 56.8 6.9 3.8 4 1 0 4 4 4 1 O-Antigen ligase PglL_A PF15864.5 AIM23776.1 - 1.4e-08 34.2 3.0 1.4e-08 34.2 3.0 5.5 5 0 0 5 5 5 1 Protein glycosylation ligase CDH PF02611.15 AIM23777.1 - 1e-73 247.7 0.0 1.2e-73 247.5 0.0 1.0 1 0 0 1 1 1 1 CDP-diacylglycerol pyrophosphatase HIT PF01230.23 AIM23777.1 - 0.22 12.3 0.0 0.4 11.4 0.0 1.5 1 0 0 1 1 1 0 HIT domain PmbA_TldD PF01523.16 AIM23778.1 - 4.1e-71 240.1 0.2 5.6e-71 239.6 0.2 1.2 1 0 0 1 1 1 1 Putative modulator of DNA gyrase CN_hydrolase PF00795.22 AIM23779.1 - 3.6e-46 157.6 0.1 4.2e-46 157.4 0.1 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Lipase_GDSL_2 PF13472.6 AIM23779.1 - 0.021 15.2 0.3 0.26 11.7 0.1 2.2 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase family RNase_E_G PF10150.9 AIM23780.1 - 3.1e-100 335.0 0.4 5.4e-100 334.3 0.4 1.4 1 0 0 1 1 1 1 Ribonuclease E/G family S1 PF00575.23 AIM23780.1 - 7.6e-08 32.6 0.2 4.8e-07 30.0 0.0 2.2 2 0 0 2 2 2 1 S1 RNA binding domain HARE-HTH PF05066.13 AIM23780.1 - 0.011 16.1 0.0 0.26 11.7 0.0 3.0 3 0 0 3 3 3 0 HB1, ASXL, restriction endonuclease HTH domain Maf PF02545.14 AIM23781.1 - 6e-58 195.4 0.1 6.7e-58 195.2 0.1 1.0 1 0 0 1 1 1 1 Maf-like protein MreD PF04093.12 AIM23782.1 - 8.4e-44 149.5 23.3 9.4e-44 149.3 23.3 1.0 1 0 0 1 1 1 1 rod shape-determining protein MreD MreC PF04085.14 AIM23783.1 - 6.4e-37 126.8 0.3 1e-36 126.1 0.3 1.3 1 0 0 1 1 1 1 rod shape-determining protein MreC MreB_Mbl PF06723.13 AIM23784.1 - 3.7e-117 390.8 1.2 4.6e-117 390.5 1.2 1.0 1 0 0 1 1 1 1 MreB/Mbl protein HSP70 PF00012.20 AIM23784.1 - 1.9e-13 49.5 0.0 1.9e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein FtsA PF14450.6 AIM23784.1 - 2.2e-11 44.1 0.0 4.3e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Cell division protein FtsA Actin PF00022.19 AIM23784.1 - 4.7e-08 32.1 0.0 0.00038 19.2 0.0 2.1 1 1 0 2 2 2 2 Actin PilM_2 PF11104.8 AIM23784.1 - 6.1e-08 32.1 0.0 0.0016 17.6 0.0 2.3 2 0 0 2 2 2 2 Type IV pilus assembly protein PilM; Ppx-GppA PF02541.16 AIM23784.1 - 0.00044 19.8 0.1 0.00073 19.1 0.1 1.4 1 0 0 1 1 1 1 Ppx/GppA phosphatase family EutA PF06277.11 AIM23784.1 - 0.002 17.1 0.2 0.0025 16.7 0.2 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutA DDR PF08841.10 AIM23784.1 - 0.0053 15.8 1.5 0.011 14.8 0.4 1.9 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain MreB_Mbl PF06723.13 AIM23785.1 - 5.1e-23 81.4 0.0 5.9e-23 81.2 0.0 1.0 1 0 0 1 1 1 1 MreB/Mbl protein EAL PF00563.20 AIM23786.1 - 7.2e-39 133.7 0.7 1.1e-38 133.2 0.1 1.6 2 0 0 2 2 2 1 EAL domain GAPES4 PF17157.4 AIM23786.1 - 2.8e-24 85.4 0.0 8.7e-24 83.8 0.0 1.9 2 0 0 2 2 2 1 Gammaproteobacterial periplasmic sensor domain GGDEF PF00990.21 AIM23786.1 - 5.9e-24 84.6 0.1 1.2e-23 83.6 0.1 1.6 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Hrs_helical PF12210.8 AIM23786.1 - 0.1 13.2 0.1 1.5 9.4 0.0 2.4 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Proton_antipo_N PF00662.20 AIM23786.1 - 0.5 10.5 4.5 2 8.5 1.2 2.9 3 0 0 3 3 3 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus ADH_zinc_N PF00107.26 AIM23787.1 - 1.4e-14 54.2 0.0 2.4e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AIM23787.1 - 1.6e-06 28.0 0.0 7.9e-06 25.7 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.21 AIM23787.1 - 0.0025 17.3 0.1 0.0039 16.7 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AlaDh_PNT_C PF01262.21 AIM23787.1 - 0.0035 16.7 0.4 0.0054 16.0 0.4 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GDP_Man_Dehyd PF16363.5 AIM23787.1 - 0.015 14.7 0.1 0.021 14.2 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 AIM23787.1 - 0.017 14.6 0.1 0.03 13.8 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase PALP PF00291.25 AIM23787.1 - 0.041 13.3 0.6 0.09 12.2 0.6 1.7 1 1 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme NmrA PF05368.13 AIM23787.1 - 0.063 12.8 0.0 0.089 12.3 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Oxidored_molyb PF00174.19 AIM23788.1 - 3.4e-29 101.7 0.0 5.7e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Ferric_reduct PF01794.19 AIM23789.1 - 3.4e-14 53.0 7.5 3.4e-14 53.0 7.5 2.0 2 1 1 3 3 3 1 Ferric reductase like transmembrane component DUF3021 PF11457.8 AIM23789.1 - 1.4 9.3 6.8 0.46 10.8 2.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) DHquinase_II PF01220.19 AIM23790.1 - 2.7e-62 208.5 0.1 3e-62 208.3 0.1 1.0 1 0 0 1 1 1 1 Dehydroquinase class II Biotin_lipoyl PF00364.22 AIM23791.1 - 1.1e-26 92.4 0.7 1.1e-26 92.4 0.7 1.6 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 AIM23791.1 - 1.3e-05 24.9 7.4 0.003 17.3 0.2 2.9 3 1 1 4 4 4 2 Biotin-lipoyl like RnfC_N PF13375.6 AIM23791.1 - 0.0034 17.3 1.8 0.0046 16.9 0.3 1.9 1 1 0 2 2 2 1 RnfC Barrel sandwich hybrid domain GCV_H PF01597.19 AIM23791.1 - 0.0071 16.2 0.9 0.022 14.7 0.2 2.1 2 2 0 2 2 2 1 Glycine cleavage H-protein YqfD PF06898.11 AIM23791.1 - 0.035 12.9 0.9 0.15 10.9 0.1 1.9 1 1 1 2 2 2 0 Putative stage IV sporulation protein YqfD CPSase_L_D2 PF02786.17 AIM23792.1 - 2.4e-86 288.6 0.1 3.6e-86 288.0 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 AIM23792.1 - 2e-44 150.6 0.1 5e-44 149.4 0.1 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 AIM23792.1 - 1.2e-38 131.5 0.0 2.5e-38 130.5 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_3 PF02655.14 AIM23792.1 - 1.7e-09 37.9 0.0 3.5e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 AIM23792.1 - 4.7e-09 36.0 0.0 9.1e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 AIM23792.1 - 2e-08 34.1 0.0 4.6e-08 32.9 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus GARS_A PF01071.19 AIM23792.1 - 0.003 17.4 0.0 0.0055 16.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 AIM23792.1 - 0.0066 16.1 0.2 0.063 12.9 0.0 2.5 2 1 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.6 AIM23792.1 - 0.0094 15.6 0.0 0.037 13.6 0.0 2.1 2 1 0 2 2 2 1 ATP-grasp domain DUF997 PF06196.12 AIM23793.1 - 4e-29 100.4 0.3 4.5e-29 100.3 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF997) SSF PF00474.17 AIM23794.1 - 6.4e-132 440.2 26.0 7.6e-132 440.0 26.0 1.0 1 0 0 1 1 1 1 Sodium:solute symporter family PrmA PF06325.13 AIM23795.1 - 9.9e-103 343.6 0.0 1.1e-102 343.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 AIM23795.1 - 1e-09 38.3 0.0 1.4e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AIM23795.1 - 8e-09 35.3 0.0 1.2e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 AIM23795.1 - 6.6e-08 33.2 0.0 1.5e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AIM23795.1 - 8.5e-06 26.3 0.0 2.2e-05 25.0 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AIM23795.1 - 1.5e-05 24.9 0.0 2.3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 AIM23795.1 - 7.1e-05 22.5 0.0 0.00014 21.6 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_12 PF08242.12 AIM23795.1 - 0.00011 22.9 0.0 0.00021 22.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 AIM23795.1 - 0.00011 22.1 0.0 0.00018 21.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 AIM23795.1 - 0.00031 20.8 0.0 0.00048 20.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.18 AIM23795.1 - 0.00032 20.5 0.0 0.0004 20.2 0.0 1.2 1 0 0 1 1 1 1 DNA methylase Met_10 PF02475.16 AIM23795.1 - 0.00035 20.4 0.0 0.00052 19.8 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.19 AIM23795.1 - 0.0004 20.2 0.0 0.00061 19.6 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.11 AIM23795.1 - 0.0072 15.3 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) UPF0020 PF01170.18 AIM23795.1 - 0.0076 16.0 0.6 0.027 14.1 0.6 1.8 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 CMAS PF02353.20 AIM23795.1 - 0.02 14.2 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_15 PF09445.10 AIM23795.1 - 0.021 14.4 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Dus PF01207.17 AIM23796.1 - 7.4e-105 350.5 0.0 8.8e-105 350.2 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 AIM23796.1 - 6.4e-05 22.5 0.0 0.00019 21.0 0.1 1.7 1 1 0 1 1 1 1 Histidine biosynthesis protein DHO_dh PF01180.21 AIM23796.1 - 0.00012 21.4 0.0 0.022 14.0 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase SOR_SNZ PF01680.17 AIM23796.1 - 0.0098 15.7 0.5 1.5 8.6 0.1 2.3 1 1 1 2 2 2 2 SOR/SNZ family NMO PF03060.15 AIM23796.1 - 0.012 15.1 1.6 0.022 14.1 0.1 2.0 2 0 0 2 2 2 0 Nitronate monooxygenase PEP_mutase PF13714.6 AIM23796.1 - 0.015 14.8 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase NanE PF04131.14 AIM23796.1 - 0.021 14.0 0.0 0.045 12.9 0.0 1.6 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase MR_MLE_C PF13378.6 AIM23796.1 - 0.06 12.9 0.1 0.31 10.6 0.0 2.0 1 1 1 2 2 2 0 Enolase C-terminal domain-like Pterin_bind PF00809.22 AIM23796.1 - 0.075 12.7 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Pterin binding enzyme ThiG PF05690.14 AIM23796.1 - 0.25 10.6 1.2 0.41 9.9 0.1 1.9 2 1 0 2 2 2 0 Thiazole biosynthesis protein ThiG HTH_8 PF02954.19 AIM23797.1 - 2.6e-14 52.7 0.4 3.8e-14 52.2 0.4 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family Phage_NinH PF06322.11 AIM23797.1 - 0.00053 19.8 0.1 0.0011 18.8 0.1 1.5 1 0 0 1 1 1 1 Phage NinH protein DUF3333 PF11812.8 AIM23797.1 - 0.025 14.8 0.3 0.029 14.6 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3333) HTH_30 PF13556.6 AIM23797.1 - 0.1 12.4 0.1 0.26 11.1 0.0 1.7 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain Inhibitor_I24 PF10465.9 AIM23797.1 - 0.14 12.1 0.1 0.17 11.9 0.1 1.1 1 0 0 1 1 1 0 PinA peptidase inhibitor DUF2574 PF10836.8 AIM23798.1 - 0.053 13.4 0.0 0.062 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2574) DUF3316 PF11777.8 AIM23798.1 - 0.1 12.7 0.5 0.12 12.4 0.5 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3316) LPAM_1 PF08139.12 AIM23798.1 - 0.15 12.6 1.3 0.25 11.9 1.3 1.3 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site YtxH PF12732.7 AIM23798.1 - 0.61 10.7 13.7 0.67 10.5 5.4 2.3 1 1 1 2 2 2 0 YtxH-like protein DUF883 PF05957.13 AIM23798.1 - 1.3 9.6 8.1 2 9.1 3.0 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Presenilin PF01080.17 AIM23798.1 - 4.5 5.9 4.4 4.9 5.8 4.4 1.0 1 0 0 1 1 1 0 Presenilin Lip_A_acyltrans PF03279.13 AIM23799.1 - 2e-100 335.8 0.2 2.2e-100 335.6 0.2 1.0 1 0 0 1 1 1 1 Bacterial lipid A biosynthesis acyltransferase DUF374 PF04028.13 AIM23799.1 - 0.067 12.7 0.0 0.13 11.8 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF374) GATase PF00117.28 AIM23800.1 - 1.8e-12 47.5 0.0 2.2e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 AIM23800.1 - 0.042 13.5 0.0 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain AMP-binding PF00501.28 AIM23801.1 - 0 1616.9 0.0 1.5e-108 363.2 0.0 5.4 5 0 0 5 5 5 5 AMP-binding enzyme Condensation PF00668.20 AIM23801.1 - 0 1148.1 0.0 1.6e-104 350.1 0.0 6.2 6 0 0 6 6 6 6 Condensation domain AMP-binding_C PF13193.6 AIM23801.1 - 4.1e-73 242.4 8.5 4.2e-15 56.5 0.1 6.6 6 0 0 6 6 6 5 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 AIM23801.1 - 9.3e-62 205.3 7.2 1.1e-11 44.9 0.0 6.3 6 0 0 6 6 6 5 Phosphopantetheine attachment site Thioesterase PF00975.20 AIM23801.1 - 6.9e-23 82.0 9.3 3.2e-22 79.8 0.1 4.0 4 0 0 4 4 4 1 Thioesterase domain Formyl_trans_C PF02911.18 AIM23801.1 - 0.00029 21.0 0.0 0.00085 19.5 0.0 1.8 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Peptidase_S48 PF03574.15 AIM23801.1 - 0.0015 18.8 0.1 4 7.6 0.0 4.5 5 0 0 5 5 5 1 Peptidase family S48 zf-RING_5 PF14634.6 AIM23801.1 - 1.2 9.1 2.3 33 4.5 0.3 2.4 2 0 0 2 2 2 0 zinc-RING finger domain DUF5122 PF17164.4 AIM23801.1 - 1.6 9.1 7.1 88 3.5 0.3 5.3 5 0 0 5 5 5 0 Domain of unknown function (DUF5122) beta-propeller LrgB PF04172.16 AIM23802.1 - 4.9e-71 238.7 12.1 5.5e-71 238.5 12.1 1.0 1 0 0 1 1 1 1 LrgB-like family Glucos_trans_II PF14264.6 AIM23802.1 - 0.42 9.9 9.0 0.079 12.3 5.5 1.5 2 0 0 2 2 2 0 Glucosyl transferase GtrII LrgA PF03788.14 AIM23803.1 - 1.9e-25 88.7 13.3 1.9e-25 88.7 13.3 1.5 1 1 0 1 1 1 1 LrgA family LysR_substrate PF03466.20 AIM23804.1 - 9.5e-44 149.3 0.1 1.3e-43 148.9 0.1 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM23804.1 - 1.9e-22 79.0 0.4 5.7e-22 77.4 0.3 1.9 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AIM23804.1 - 0.0038 17.0 0.2 0.017 14.9 0.2 2.0 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain MarR PF01047.22 AIM23804.1 - 0.043 13.7 0.0 0.13 12.2 0.0 1.9 1 0 0 1 1 1 0 MarR family Fe_dep_repress PF01325.19 AIM23804.1 - 0.15 12.3 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Na_H_Exchanger PF00999.21 AIM23805.1 - 3.9e-76 256.3 42.0 4.7e-76 256.0 42.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Xan_ur_permease PF00860.20 AIM23806.1 - 9e-83 278.1 50.6 1.1e-82 277.8 50.6 1.1 1 0 0 1 1 1 1 Permease family MFS_MOT1 PF16983.5 AIM23806.1 - 0.0061 17.0 15.1 0.0061 17.0 15.1 4.0 3 1 1 4 4 4 2 Molybdate transporter of MFS superfamily Glyoxalase PF00903.25 AIM23807.1 - 0.026 14.7 0.1 0.18 12.0 0.1 1.9 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily MHC_I_2 PF14586.6 AIM23807.1 - 0.15 11.9 0.0 0.19 11.6 0.0 1.1 1 0 0 1 1 1 0 Class I Histocompatibility antigen, NKG2D ligand, domains 1 and 2 GST_N PF02798.20 AIM23808.1 - 1.1e-16 61.0 0.0 2.1e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 AIM23808.1 - 3.5e-13 49.7 0.0 6.8e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AIM23808.1 - 5.6e-10 39.4 0.0 1.1e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 AIM23808.1 - 8.5e-09 35.5 0.0 1.6e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 AIM23808.1 - 7.5e-07 29.3 0.0 1.4e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 AIM23808.1 - 0.0023 17.9 0.0 0.0043 17.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 AIM23808.1 - 0.11 13.3 0.0 0.27 12.0 0.0 1.8 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain Lipocalin_5 PF13924.6 AIM23809.1 - 2.5e-39 134.3 0.0 2.8e-39 134.1 0.0 1.0 1 0 0 1 1 1 1 Lipocalin-like domain DUF1471 PF07338.13 AIM23810.1 - 3e-15 55.9 1.3 4.3e-15 55.4 1.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1471) ChapFlgA_N PF17656.1 AIM23810.1 - 0.12 12.6 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 FlgA N-terminal domain adh_short_C2 PF13561.6 AIM23811.1 - 3.2e-62 210.2 6.7 3.9e-62 209.9 6.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AIM23811.1 - 4.8e-54 182.8 3.7 5.7e-54 182.5 3.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AIM23811.1 - 1.4e-07 31.6 2.6 2.2e-07 31.0 2.6 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AIM23811.1 - 0.0031 17.0 0.6 0.0058 16.1 0.6 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 AIM23811.1 - 0.008 15.5 0.3 0.014 14.7 0.3 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1471 PF07338.13 AIM23812.1 - 2.6e-08 33.7 1.6 3.3e-08 33.4 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1471) DUF4730 PF15873.5 AIM23812.1 - 0.025 14.8 0.6 0.033 14.5 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4730) Cyclase PF04199.13 AIM23813.1 - 2e-27 96.1 0.0 2.4e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Putative cyclase SSB PF00436.25 AIM23814.1 - 8.2e-44 147.9 0.6 1e-43 147.6 0.6 1.1 1 0 0 1 1 1 1 Single-strand binding protein family UvrA_inter PF17760.1 AIM23815.1 - 7.2e-39 132.2 0.0 2.2e-38 130.6 0.0 1.9 1 0 0 1 1 1 1 UvrA interaction domain UvrA_DNA-bind PF17755.1 AIM23815.1 - 9.8e-36 122.5 0.0 2.4e-34 118.0 0.0 2.8 3 0 0 3 3 2 1 UvrA DNA-binding domain ABC_tran PF00005.27 AIM23815.1 - 5.4e-22 78.8 0.0 1.5e-05 25.5 0.0 5.0 4 1 0 4 4 4 4 ABC transporter SMC_N PF02463.19 AIM23815.1 - 3.9e-11 42.8 0.1 0.051 13.0 0.0 4.2 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AIM23815.1 - 1.4e-07 31.2 0.2 0.0012 18.5 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 AIM23815.1 - 1.4e-06 28.8 3.4 0.033 14.6 0.1 3.9 4 2 0 4 4 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 AIM23815.1 - 2.3e-06 27.6 0.0 0.0077 16.2 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase DnaJ_CXXCXGXG PF00684.19 AIM23815.1 - 1.4e-05 25.4 3.3 0.013 15.9 0.3 3.5 3 0 0 3 3 3 1 DnaJ central domain AAA_22 PF13401.6 AIM23815.1 - 2.7e-05 24.5 1.5 1.2 9.4 0.0 4.2 4 1 0 4 4 4 2 AAA domain AAA_23 PF13476.6 AIM23815.1 - 0.0002 21.9 5.3 0.39 11.2 0.5 3.2 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.6 AIM23815.1 - 0.00043 19.9 0.5 0.21 11.2 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.6 AIM23815.1 - 0.00062 20.3 0.3 2.9 8.4 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 AIM23815.1 - 0.0014 18.8 0.0 2.8 8.1 0.0 3.2 3 0 0 3 3 2 1 AAA domain cobW PF02492.19 AIM23815.1 - 0.0014 18.3 0.4 0.13 11.8 0.1 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 AIM23815.1 - 0.0015 18.4 0.0 0.3 11.0 0.0 2.5 2 0 0 2 2 2 1 NACHT domain APS_kinase PF01583.20 AIM23815.1 - 0.0034 17.3 0.2 1.5 8.7 0.0 3.1 3 0 0 3 3 2 1 Adenylylsulphate kinase T2SSE PF00437.20 AIM23815.1 - 0.0055 15.8 0.3 3.8 6.5 0.0 2.8 3 0 0 3 3 3 2 Type II/IV secretion system protein DUF2075 PF09848.9 AIM23815.1 - 0.0055 16.0 0.0 0.94 8.7 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 AIM23815.1 - 0.0057 16.4 0.0 0.4 10.4 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 AIM23815.1 - 0.01 15.6 0.1 8.6 6.0 0.0 3.4 3 0 0 3 3 3 0 AAA domain ATPase PF06745.13 AIM23815.1 - 0.022 14.1 0.0 7.9 5.8 0.0 2.4 2 0 0 2 2 2 0 KaiC ATPase_2 PF01637.18 AIM23815.1 - 0.032 14.2 0.0 2.9 7.7 0.0 2.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 AIM23815.1 - 0.036 14.1 0.0 15 5.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_21 PF13304.6 AIM23815.1 - 0.04 13.7 7.8 6.4 6.5 0.0 4.1 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 AIM23815.1 - 0.047 13.4 0.2 9.2 5.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 AIM23815.1 - 0.057 13.5 0.0 3.3 7.8 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF2083 PF09856.9 AIM23815.1 - 0.063 13.1 0.0 0.23 11.3 0.0 1.9 2 0 0 2 2 2 0 Predicted transcriptional regulator (DUF2083) AAA_7 PF12775.7 AIM23815.1 - 0.075 12.5 0.0 17 4.9 0.0 2.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_28 PF13521.6 AIM23815.1 - 0.1 12.9 0.0 13 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 AIM23815.1 - 0.1 11.5 0.1 2.1 7.3 0.1 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 AIM23815.1 - 0.18 11.7 0.7 4.2 7.3 0.1 3.0 3 0 0 3 3 3 0 NTPase Zn-ribbon_8 PF09723.10 AIM23815.1 - 6.5 7.0 9.5 6.3 7.0 0.3 3.6 3 0 0 3 3 3 0 Zinc ribbon domain MipA PF06629.12 AIM23816.1 - 4.5e-37 128.4 7.4 5.3e-37 128.2 7.4 1.0 1 0 0 1 1 1 1 MltA-interacting protein MipA OMP_b-brl PF13505.6 AIM23816.1 - 1.6 8.8 11.0 5.2 7.2 1.3 2.7 2 1 0 2 2 2 0 Outer membrane protein beta-barrel domain Peptidase_M48 PF01435.18 AIM23817.1 - 3.2e-16 59.7 0.0 8.7e-11 42.0 0.1 2.1 1 1 1 2 2 2 2 Peptidase family M48 DUF45 PF01863.17 AIM23817.1 - 0.021 14.9 1.8 0.039 14.0 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF45 Mac PF12464.8 AIM23818.1 - 4e-16 59.0 0.4 6.2e-16 58.4 0.4 1.2 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.6 AIM23818.1 - 5.5e-16 58.0 13.5 1.6e-12 46.9 2.9 3.2 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 AIM23818.1 - 8e-14 50.7 14.0 3.3e-11 42.5 5.0 3.2 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) YjbR PF04237.13 AIM23819.1 - 1.3e-17 64.1 0.0 1.5e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 YjbR UPF0047 PF01894.17 AIM23820.1 - 4.4e-37 126.8 0.0 5e-37 126.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 DUF1059 PF06348.11 AIM23820.1 - 0.02 15.1 0.0 0.039 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1059) Aminotran_1_2 PF00155.21 AIM23821.1 - 2.4e-82 277.0 0.0 2.7e-82 276.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II OmpA_like PF16961.5 AIM23821.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative OmpA-OmpF-like porin family AsnC_trans_reg PF01037.21 AIM23822.1 - 1.9e-19 69.4 0.2 3.1e-19 68.7 0.2 1.3 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_AsnC-type PF13404.6 AIM23822.1 - 2.4e-14 52.9 0.2 5e-14 51.8 0.2 1.6 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 AIM23822.1 - 1.4e-12 46.9 0.6 1.4e-12 46.9 0.6 1.6 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 AIM23822.1 - 0.0023 17.9 0.3 0.0069 16.3 0.3 1.8 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain MarR PF01047.22 AIM23822.1 - 0.003 17.5 0.2 0.0062 16.5 0.2 1.5 1 0 0 1 1 1 1 MarR family HTH_IclR PF09339.10 AIM23822.1 - 0.031 14.1 0.5 0.061 13.1 0.5 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_20 PF12840.7 AIM23822.1 - 0.058 13.5 0.1 0.19 11.8 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_9 PF08221.11 AIM23822.1 - 0.078 13.1 0.7 0.55 10.4 0.2 2.4 2 1 1 3 3 3 0 RNA polymerase III subunit RPC82 helix-turn-helix domain TrmB PF01978.19 AIM23822.1 - 0.092 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB SBP_bac_3 PF00497.20 AIM23823.1 - 1.5e-42 145.6 0.0 1.7e-42 145.4 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 AIM23823.1 - 0.00023 21.3 0.1 0.046 13.9 0.0 2.9 2 1 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site Ala_racemase_N PF01168.20 AIM23824.1 - 2.2e-71 240.0 0.0 2.7e-71 239.7 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Ala_racemase_C PF00842.21 AIM23824.1 - 2e-39 134.2 0.1 3.1e-39 133.6 0.1 1.3 1 0 0 1 1 1 1 Alanine racemase, C-terminal domain DnaB_C PF03796.15 AIM23825.1 - 1.3e-111 372.0 0.8 1.8e-111 371.6 0.8 1.2 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain DnaB PF00772.21 AIM23825.1 - 7.2e-36 122.4 0.0 1.6e-35 121.3 0.0 1.6 1 0 0 1 1 1 1 DnaB-like helicase N terminal domain AAA_25 PF13481.6 AIM23825.1 - 7.7e-11 41.9 0.0 1.2e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 AIM23825.1 - 0.00092 18.6 0.0 0.0032 16.9 0.0 1.8 1 1 0 1 1 1 1 KaiC AAA_33 PF13671.6 AIM23825.1 - 0.0051 17.0 0.0 0.027 14.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain ADH_zinc_N PF00107.26 AIM23826.1 - 7.8e-27 93.8 0.3 1.8e-26 92.7 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AIM23826.1 - 1.9e-14 54.8 0.0 3.1e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AIM23826.1 - 8.9e-10 38.4 0.1 2e-09 37.3 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Phageshock_PspG PF09583.10 AIM23827.1 - 3.6e-26 91.2 23.2 4e-26 91.1 23.2 1.0 1 0 0 1 1 1 1 Phage shock protein G (Phageshock_PspG) DUF2933 PF11666.8 AIM23827.1 - 1.6 8.8 10.0 0.18 11.9 5.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2933) Dus PF01207.17 AIM23828.1 - 2.2e-94 316.1 0.0 2.5e-94 315.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 AIM23828.1 - 0.046 13.2 0.0 0.14 11.6 0.0 1.6 2 0 0 2 2 2 0 Histidine biosynthesis protein TPR_17 PF13431.6 AIM23829.1 - 1.9e-11 43.5 3.3 4e-05 23.7 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 AIM23829.1 - 4.3e-11 42.1 2.2 0.0016 18.4 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 AIM23829.1 - 1.7e-09 38.0 0.4 0.00012 22.5 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 AIM23829.1 - 4.1e-08 32.7 3.6 0.0029 17.4 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 AIM23829.1 - 7.7e-08 32.5 1.0 0.014 16.2 0.0 3.7 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 AIM23829.1 - 5.1e-07 30.2 1.5 0.0004 21.0 0.2 3.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 AIM23829.1 - 1.5e-06 27.8 1.9 4.4e-05 23.1 0.2 2.5 2 1 0 2 2 2 1 TPR repeat TPR_12 PF13424.6 AIM23829.1 - 1.8e-06 28.1 2.0 0.028 14.7 0.1 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 AIM23829.1 - 4.3e-05 23.4 2.3 0.23 11.8 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 AIM23829.1 - 0.00035 20.9 2.3 0.64 10.8 0.0 3.3 4 0 0 4 4 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 AIM23829.1 - 0.0009 19.4 0.4 0.0084 16.3 0.1 2.2 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 CBM_14 PF01607.24 AIM23829.1 - 0.0016 18.5 0.1 0.0029 17.7 0.1 1.4 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain TPR_10 PF13374.6 AIM23829.1 - 0.0028 17.5 5.9 0.53 10.2 0.4 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 AIM23829.1 - 0.004 17.7 2.1 13 6.7 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 AIM23829.1 - 0.0086 16.0 0.7 1.5 8.7 0.0 2.2 1 1 0 2 2 2 1 Virulence factor membrane-bound polymerase, C-terminal PPR PF01535.20 AIM23829.1 - 0.052 13.8 0.3 1 9.8 0.0 3.1 4 1 0 4 4 4 0 PPR repeat TPR_3 PF07720.12 AIM23829.1 - 0.068 13.2 0.2 0.2 11.7 0.2 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 AIM23829.1 - 0.18 11.9 0.9 34 4.8 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Sigma70_r4_2 PF08281.12 AIM23830.1 - 6.9e-14 51.3 0.5 9.3e-14 50.8 0.5 1.2 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AIM23830.1 - 1.1e-07 31.2 0.0 1.6e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 AIM23830.1 - 8.6e-06 25.8 0.1 9.9e-06 25.6 0.1 1.0 1 0 0 1 1 1 1 ECF sigma factor HTH_23 PF13384.6 AIM23830.1 - 0.038 13.8 0.0 0.067 13.0 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain TnsD PF15978.5 AIM23830.1 - 0.079 11.9 0.0 0.08 11.9 0.0 1.1 1 0 0 1 1 1 0 Tn7-like transposition protein D Phage_antitermQ PF06530.12 AIM23830.1 - 0.092 12.7 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Phage antitermination protein Q Hexapep PF00132.24 AIM23831.1 - 5e-17 60.9 16.8 1.3e-10 40.5 8.0 3.2 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AIM23831.1 - 6.1e-14 51.5 18.6 1e-07 31.6 8.0 2.6 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 AIM23831.1 - 1.9e-06 28.0 0.1 2.7e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase FUR PF01475.19 AIM23832.1 - 7e-16 58.5 0.3 1.1e-15 57.9 0.0 1.4 2 0 0 2 2 2 1 Ferric uptake regulator family MarR PF01047.22 AIM23832.1 - 0.0015 18.4 0.0 0.0052 16.7 0.0 1.9 1 1 0 1 1 1 1 MarR family HTH_20 PF12840.7 AIM23832.1 - 0.06 13.4 0.2 0.27 11.3 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_5 PF01022.20 AIM23832.1 - 0.07 13.0 0.0 0.54 10.2 0.0 2.2 1 1 0 1 1 1 0 Bacterial regulatory protein, arsR family CsbD PF05532.12 AIM23833.1 - 3.6e-23 81.2 9.6 4.4e-23 80.9 9.6 1.1 1 0 0 1 1 1 1 CsbD-like DUF739 PF05339.11 AIM23833.1 - 0.038 14.1 0.2 3.7 7.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF739) MatE PF01554.18 AIM23834.1 - 2.6e-48 163.7 24.7 8.7e-35 119.8 9.4 2.5 2 1 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 AIM23834.1 - 1.4e-05 25.2 16.4 1.4e-05 25.2 16.4 4.6 3 3 1 4 4 4 1 Polysaccharide biosynthesis C-terminal domain LexA_DNA_bind PF01726.16 AIM23835.1 - 7.7e-30 102.5 0.1 1.4e-29 101.7 0.1 1.4 1 0 0 1 1 1 1 LexA DNA binding domain Peptidase_S24 PF00717.23 AIM23835.1 - 1.4e-16 60.1 0.4 2.2e-16 59.6 0.4 1.3 1 0 0 1 1 1 1 Peptidase S24-like Rrf2 PF02082.20 AIM23835.1 - 0.0029 17.9 0.0 0.007 16.7 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulator HTH_Crp_2 PF13545.6 AIM23835.1 - 0.0057 16.6 0.1 0.015 15.3 0.1 1.7 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_20 PF12840.7 AIM23835.1 - 0.0083 16.2 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain GntR PF00392.21 AIM23835.1 - 0.033 13.8 0.2 0.2 11.3 0.1 2.4 2 1 0 2 2 2 0 Bacterial regulatory proteins, gntR family CSD2 PF17876.1 AIM23835.1 - 0.039 14.1 0.1 0.074 13.2 0.1 1.5 1 0 0 1 1 1 0 Cold shock domain DAGK_prokar PF01219.19 AIM23836.1 - 9.3e-35 118.5 5.4 1.1e-34 118.3 5.4 1.0 1 0 0 1 1 1 1 Prokaryotic diacylglycerol kinase Fig1 PF12351.8 AIM23836.1 - 0.38 10.6 5.3 0.35 10.8 1.0 2.1 1 1 1 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 DUF2607 PF10795.9 AIM23836.1 - 3 8.0 4.6 1.2 9.3 0.4 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF2607) DUF202 PF02656.15 AIM23836.1 - 6.7 7.2 8.6 83 3.7 8.6 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF202) DUF2976 PF11190.8 AIM23836.1 - 8.3 6.3 9.7 3 7.7 0.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2976) Acyltransferase PF01553.21 AIM23837.1 - 3.4e-26 91.5 0.0 7.2e-26 90.4 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase UbiA PF01040.18 AIM23838.1 - 3.2e-67 226.5 25.0 4e-67 226.2 25.0 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Chor_lyase PF04345.13 AIM23839.1 - 5.9e-35 120.4 0.0 7.6e-35 120.0 0.0 1.0 1 0 0 1 1 1 1 Chorismate lyase Sugar_tr PF00083.24 AIM23840.1 - 1e-28 100.4 22.4 1.1e-26 93.8 22.4 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 AIM23840.1 - 1.2e-26 93.6 47.4 3.4e-18 65.7 18.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 AIM23840.1 - 1.9e-06 26.7 9.0 1.9e-06 26.7 9.0 2.7 2 1 1 3 3 3 2 MFS/sugar transport protein DUF2069 PF09842.9 AIM23840.1 - 2.7 8.2 17.5 0.054 13.7 3.4 3.5 4 0 0 4 4 4 0 Predicted membrane protein (DUF2069) Peripla_BP_3 PF13377.6 AIM23841.1 - 4.9e-31 108.3 0.5 2.6e-29 102.7 0.1 2.2 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 AIM23841.1 - 2.7e-30 105.8 0.0 3.3e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_4 PF13407.6 AIM23841.1 - 7.2e-17 61.8 0.0 1.7e-16 60.6 0.0 1.5 2 0 0 2 2 2 1 Periplasmic binding protein domain LacI PF00356.21 AIM23841.1 - 4.2e-13 48.9 0.8 7.9e-13 48.0 0.8 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family IU_nuc_hydro PF01156.19 AIM23842.1 - 6.7e-62 209.8 0.0 7.5e-62 209.6 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase MalM PF07148.12 AIM23843.1 - 1.9e-53 179.8 0.0 2.8e-53 179.3 0.0 1.2 1 0 0 1 1 1 1 Maltose operon periplasmic protein precursor (MalM) LamB PF02264.15 AIM23844.1 - 5.3e-145 484.1 22.0 6e-145 483.9 22.0 1.0 1 0 0 1 1 1 1 LamB porin ABC_tran PF00005.27 AIM23845.1 - 2.1e-33 115.7 0.0 3.7e-33 114.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter OB_MalK PF17912.1 AIM23845.1 - 9.4e-14 52.0 0.2 5.3e-13 49.6 0.1 2.4 2 0 0 2 2 2 1 MalK OB fold domain TOBE_2 PF08402.10 AIM23845.1 - 7.4e-12 45.3 1.0 1.5e-11 44.2 0.2 2.0 2 0 0 2 2 1 1 TOBE domain RsgA_GTPase PF03193.16 AIM23845.1 - 3.3e-06 27.1 0.2 0.00031 20.7 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 AIM23845.1 - 7.2e-06 26.0 0.3 0.0043 16.9 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIM23845.1 - 2.4e-05 23.9 0.4 0.00029 20.3 0.4 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AIM23845.1 - 0.00065 20.1 0.2 0.0018 18.7 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain TOBE PF03459.17 AIM23845.1 - 0.00071 19.8 0.2 0.34 11.2 0.1 3.0 2 0 0 2 2 2 1 TOBE domain AAA_29 PF13555.6 AIM23845.1 - 0.0056 16.4 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AIM23845.1 - 0.0059 16.9 0.0 0.019 15.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 AIM23845.1 - 0.011 16.3 0.0 0.02 15.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AIM23845.1 - 0.011 15.9 0.1 0.022 14.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AIM23845.1 - 0.022 14.3 0.0 0.12 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 AIM23845.1 - 0.031 14.0 0.0 0.047 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 AIM23845.1 - 0.035 14.5 0.2 0.071 13.5 0.1 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 AIM23845.1 - 0.047 13.9 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 AIM23845.1 - 0.047 13.6 0.0 0.083 12.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain NACHT PF05729.12 AIM23845.1 - 0.068 13.1 0.1 0.16 11.9 0.0 1.6 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.23 AIM23845.1 - 0.068 13.3 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_30 PF13604.6 AIM23845.1 - 0.1 12.3 0.1 0.26 11.0 0.0 1.9 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 AIM23845.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 AIM23845.1 - 0.13 12.7 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.22 AIM23845.1 - 0.16 11.1 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_7 PF12775.7 AIM23845.1 - 0.2 11.2 0.0 0.39 10.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Alpha-amylase PF00128.24 AIM23846.1 - 3.2e-06 26.9 0.0 6.5e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 Alpha amylase, catalytic domain DUF3459 PF11941.8 AIM23846.1 - 0.022 15.0 0.3 0.022 15.0 0.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3459) SBP_bac_8 PF13416.6 AIM23847.1 - 2.8e-41 142.2 9.4 4e-41 141.7 9.4 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AIM23847.1 - 5.5e-40 138.3 13.6 7.4e-40 137.8 13.6 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AIM23847.1 - 0.0002 20.8 0.7 0.0045 16.4 0.0 2.2 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein DUF4179 PF13786.6 AIM23847.1 - 0.061 13.8 0.1 0.18 12.3 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) MalF_P2 PF14785.6 AIM23848.1 - 2.1e-62 210.0 0.1 2.7e-62 209.6 0.1 1.1 1 0 0 1 1 1 1 Maltose transport system permease protein MalF P2 domain BPD_transp_1 PF00528.22 AIM23848.1 - 3.3e-21 75.9 17.5 3.3e-21 75.9 17.5 2.9 2 2 1 3 3 3 1 Binding-protein-dependent transport system inner membrane component DUF4534 PF15049.6 AIM23848.1 - 0.0018 18.1 2.7 0.0055 16.5 2.7 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF4534) TM_PBP2_N PF16296.5 AIM23848.1 - 0.013 15.6 0.0 0.013 15.6 0.0 2.8 4 0 0 4 4 4 0 N-terminal of TM subunit in PBP-dependent ABC transporters BPD_transp_1 PF00528.22 AIM23849.1 - 1.1e-15 57.9 15.8 1.1e-15 57.9 15.8 2.2 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component PsiE PF06146.12 AIM23850.1 - 3.8e-16 59.2 6.1 3.8e-16 59.2 6.1 2.1 1 1 1 2 2 2 1 Phosphate-starvation-inducible E DUF347 PF03988.12 AIM23850.1 - 0.23 11.7 3.0 5.6 7.2 0.1 2.6 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) DUF2070 PF09843.9 AIM23850.1 - 2.4 6.3 10.6 2.9 6.1 10.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Caps_assemb_Wzi PF14052.6 AIM23851.1 - 2.3e-100 336.4 14.6 2.8e-100 336.1 14.6 1.0 1 0 0 1 1 1 1 Capsule assembly protein Wzi Prefoldin_3 PF13758.6 AIM23851.1 - 0.002 18.2 0.1 0.0035 17.4 0.1 1.3 1 0 0 1 1 1 1 Prefoldin subunit PGI PF00342.19 AIM23852.1 - 6.4e-255 846.3 0.0 7.3e-255 846.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Na_H_Exchanger PF00999.21 AIM23853.1 - 2.9e-38 131.7 44.3 3.9e-38 131.2 44.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TrkA_N PF02254.18 AIM23853.1 - 8.1e-08 32.5 0.0 1.6e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain XdhC_C PF13478.6 AIM23853.1 - 0.077 13.5 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain AA_kinase PF00696.28 AIM23854.1 - 2.2e-46 158.4 0.2 3.5e-46 157.8 0.2 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.6 AIM23854.1 - 3.7e-07 29.8 0.0 0.011 15.5 0.0 2.7 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 AIM23854.1 - 1.1e-06 28.2 0.1 5.9e-06 26.0 0.3 2.2 2 0 0 2 2 2 1 ACT domain AAA_22 PF13401.6 AIM23854.1 - 0.079 13.2 0.2 0.19 12.0 0.2 1.6 1 0 0 1 1 1 0 AAA domain SBF PF01758.16 AIM23855.1 - 1.8e-39 135.4 18.8 1.8e-39 135.4 18.8 1.8 1 1 1 2 2 2 1 Sodium Bile acid symporter family SBF_like PF13593.6 AIM23855.1 - 1.3e-18 67.4 17.7 1.4e-18 67.3 17.7 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Mem_trans PF03547.18 AIM23855.1 - 0.15 10.4 14.8 0.055 11.9 3.8 2.6 1 1 1 3 3 3 0 Membrane transport protein ShlB PF03865.13 AIM23856.1 - 1.5e-95 320.3 8.8 1.9e-95 319.9 8.8 1.1 1 0 0 1 1 1 1 Haemolysin secretion/activation protein ShlB/FhaC/HecB POTRA_2 PF08479.11 AIM23856.1 - 7.8e-20 70.5 0.1 3.5e-19 68.4 0.0 2.2 2 0 0 2 2 2 1 POTRA domain, ShlB-type POTRA_3 PF17287.2 AIM23856.1 - 4.6e-15 54.8 0.1 1.5e-14 53.1 0.1 2.0 1 0 0 1 1 1 1 POTRA domain POTRA PF07244.15 AIM23856.1 - 0.0072 16.9 0.0 0.035 14.7 0.0 2.1 2 0 0 2 2 2 1 Surface antigen variable number repeat Fil_haemagg_2 PF13332.6 AIM23857.1 - 8.1e-84 279.9 170.7 1.5e-25 90.3 14.6 11.2 7 3 3 10 10 10 9 Hemagglutinin repeat Haemagg_act PF05860.13 AIM23857.1 - 2.5e-30 104.9 3.1 2.5e-30 104.9 3.1 3.7 3 0 0 3 3 3 1 haemagglutination activity domain Fil_haemagg PF05594.14 AIM23857.1 - 0.0057 17.2 0.8 0.0057 17.2 0.8 17.0 5 2 2 7 7 7 1 Haemagluttinin repeat Na_Pi_cotrans PF02690.15 AIM23858.1 - 3.2e-43 147.2 25.4 2.3e-34 118.5 10.6 2.2 2 0 0 2 2 2 2 Na+/Pi-cotransporter PhoU PF01895.19 AIM23858.1 - 8.4e-09 35.8 3.1 2.1e-07 31.3 1.9 2.4 2 0 0 2 2 2 1 PhoU domain ABC_tran PF00005.27 AIM23859.1 - 7e-35 120.5 0.0 1.2e-34 119.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIM23859.1 - 8.1e-11 42.3 0.6 2.6e-05 24.2 0.2 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIM23859.1 - 0.00031 20.2 0.0 0.1 12.0 0.1 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AIM23859.1 - 0.00034 21.1 0.4 0.0015 18.9 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 AIM23859.1 - 0.00048 20.1 0.0 0.0013 18.7 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase TOBE_2 PF08402.10 AIM23859.1 - 0.00093 19.3 0.5 0.0026 17.9 0.3 1.9 2 0 0 2 2 2 1 TOBE domain AAA_29 PF13555.6 AIM23859.1 - 0.0015 18.2 0.0 0.0071 16.1 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AIM23859.1 - 0.0021 18.6 0.3 0.0043 17.6 0.0 1.5 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 AIM23859.1 - 0.0029 17.0 0.0 0.0054 16.1 0.0 1.5 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 AIM23859.1 - 0.0039 16.8 0.1 0.081 12.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 AIM23859.1 - 0.0071 16.6 1.3 0.041 14.2 1.3 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AIM23859.1 - 0.018 15.2 0.2 0.072 13.3 0.2 1.9 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 AIM23859.1 - 0.023 14.6 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA PF00004.29 AIM23859.1 - 0.029 14.8 0.3 0.19 12.1 0.3 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AIM23859.1 - 0.037 14.0 0.1 0.095 12.7 0.1 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 AIM23859.1 - 0.055 13.2 0.0 0.079 12.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AIM23859.1 - 0.076 13.6 0.1 0.3 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 AIM23859.1 - 0.1 12.3 0.1 0.66 9.7 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein TniB PF05621.11 AIM23859.1 - 0.11 11.9 0.1 3.1 7.2 0.1 2.2 2 0 0 2 2 2 0 Bacterial TniB protein ATPase PF06745.13 AIM23859.1 - 0.15 11.3 0.3 2.9 7.2 0.1 2.1 2 0 0 2 2 2 0 KaiC AAA_28 PF13521.6 AIM23859.1 - 0.33 11.2 1.0 0.55 10.5 0.2 1.7 2 0 0 2 2 2 0 AAA domain BPD_transp_1 PF00528.22 AIM23860.1 - 4e-13 49.5 16.0 4e-13 49.5 16.0 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component GP41 PF00517.17 AIM23860.1 - 0.74 9.7 2.7 1.6 8.6 2.7 1.5 1 0 0 1 1 1 0 Retroviral envelope protein BPD_transp_1 PF00528.22 AIM23861.1 - 9.8e-08 31.9 27.8 8.8e-07 28.8 27.8 2.2 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component Sarcolipin PF05366.11 AIM23861.1 - 0.25 11.1 2.0 0.49 10.1 0.4 2.3 2 0 0 2 2 2 0 Sarcolipin Phosphodiest PF01663.22 AIM23862.1 - 3.8e-15 56.3 0.1 3.2e-13 50.0 0.1 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase PglZ PF08665.12 AIM23862.1 - 0.00042 20.5 0.0 0.028 14.5 0.0 2.8 2 1 0 3 3 3 1 PglZ domain Metalloenzyme PF01676.18 AIM23862.1 - 0.00058 19.3 0.0 0.0018 17.7 0.0 1.7 2 0 0 2 2 2 1 Metalloenzyme superfamily SBP_bac_6 PF13343.6 AIM23863.1 - 1.8e-35 122.5 0.5 1.8e-35 122.5 0.5 1.4 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 AIM23863.1 - 2.5e-14 53.7 4.5 2.5e-14 53.7 4.5 1.7 1 1 1 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 AIM23863.1 - 1.2e-07 31.8 0.9 4e-07 30.0 0.0 1.9 1 1 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AIM23863.1 - 9.9e-06 25.7 9.4 1.4e-05 25.2 8.7 1.7 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein UTRA PF07702.13 AIM23864.1 - 1.2e-36 125.7 0.2 1.7e-36 125.2 0.2 1.2 1 0 0 1 1 1 1 UTRA domain GntR PF00392.21 AIM23864.1 - 1.1e-16 60.2 0.1 1.8e-16 59.6 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_Crp_2 PF13545.6 AIM23864.1 - 0.019 15.0 0.0 0.043 13.8 0.0 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_24 PF13412.6 AIM23864.1 - 0.16 11.6 0.1 20 4.8 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Met_synt_B12 PF02965.17 AIM23865.1 - 6.4e-128 426.0 0.1 1.2e-127 425.1 0.1 1.5 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain S-methyl_trans PF02574.16 AIM23865.1 - 3.6e-80 269.6 0.1 6.8e-80 268.7 0.1 1.5 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Pterin_bind PF00809.22 AIM23865.1 - 6.2e-63 212.7 1.6 2.7e-62 210.6 0.6 2.6 3 0 0 3 3 3 1 Pterin binding enzyme B12-binding_2 PF02607.17 AIM23865.1 - 1.6e-24 86.2 2.3 3.5e-24 85.0 0.2 2.6 2 0 0 2 2 2 1 B12 binding domain B12-binding PF02310.19 AIM23865.1 - 5e-19 68.5 0.1 2e-18 66.6 0.1 2.1 1 0 0 1 1 1 1 B12 binding domain IclR PF01614.18 AIM23866.1 - 1.7e-40 137.9 0.0 2.7e-40 137.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 AIM23866.1 - 1.6e-18 66.2 0.5 3.5e-18 65.1 0.5 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 AIM23866.1 - 0.00015 21.6 0.0 0.0003 20.6 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 AIM23866.1 - 0.00048 19.6 0.0 0.0009 18.8 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 AIM23866.1 - 0.0027 17.6 0.0 0.0063 16.4 0.0 1.6 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.20 AIM23866.1 - 0.0041 17.5 0.0 0.0098 16.2 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulator HTH_Crp_2 PF13545.6 AIM23866.1 - 0.039 13.9 0.1 0.091 12.7 0.1 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_47 PF16221.5 AIM23866.1 - 0.098 12.2 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 winged helix-turn-helix TrmB PF01978.19 AIM23866.1 - 0.16 11.9 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB SKI PF01202.22 AIM23867.1 - 2e-09 37.8 0.0 2.4e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 AIM23867.1 - 2.1e-05 24.7 0.0 3.1e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AIM23867.1 - 2.5e-05 24.8 0.0 3.5e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AIM23867.1 - 0.00018 22.0 0.0 0.00023 21.6 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.20 AIM23867.1 - 0.00042 20.2 0.0 0.00053 19.9 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_22 PF13401.6 AIM23867.1 - 0.0026 18.0 0.0 0.0038 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Ploopntkinase1 PF18748.1 AIM23867.1 - 0.032 13.8 0.0 4.7 6.7 0.0 2.1 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 Cytidylate_kin PF02224.18 AIM23867.1 - 0.035 13.9 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase DUF2075 PF09848.9 AIM23867.1 - 0.056 12.7 0.0 0.062 12.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 AIM23867.1 - 0.13 12.8 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA PF00004.29 AIM23867.1 - 0.14 12.6 0.0 0.22 12.0 0.0 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 AIM23867.1 - 0.16 11.4 0.1 0.22 11.0 0.1 1.3 1 1 0 1 1 1 0 PhoH-like protein GntP_permease PF02447.16 AIM23868.1 - 1.3e-144 482.2 43.4 1.5e-144 482.0 43.4 1.0 1 0 0 1 1 1 1 GntP family permease CitMHS PF03600.16 AIM23868.1 - 2.8e-18 66.1 37.5 4.5e-18 65.5 37.5 1.3 1 0 0 1 1 1 1 Citrate transporter Na_H_antiport_2 PF13726.6 AIM23868.1 - 0.00014 22.0 7.3 0.00014 22.0 7.3 3.4 4 1 0 4 4 4 1 Na+-H+ antiporter family DUF4271 PF14093.6 AIM23868.1 - 0.22 11.4 2.7 18 5.2 0.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4271) ILVD_EDD PF00920.21 AIM23869.1 - 6.2e-158 526.6 0.1 7.3e-158 526.4 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family zf-A20 PF01754.16 AIM23869.1 - 0.21 11.6 0.8 0.4 10.7 0.8 1.5 1 0 0 1 1 1 0 A20-like zinc finger AceK PF06315.11 AIM23870.1 - 2.8e-255 848.1 0.1 3.3e-255 847.9 0.1 1.0 1 0 0 1 1 1 1 Isocitrate dehydrogenase kinase/phosphatase (AceK) ICL PF00463.21 AIM23871.1 - 5.4e-111 371.7 2.4 4.7e-61 206.9 0.0 2.0 1 1 1 2 2 2 2 Isocitrate lyase family PEP_mutase PF13714.6 AIM23871.1 - 8.3e-19 68.0 1.2 1.9e-18 66.8 0.2 1.9 2 1 0 2 2 2 1 Phosphoenolpyruvate phosphomutase ETC_C1_NDUFA4 PF04800.12 AIM23871.1 - 0.11 12.8 1.2 0.41 10.9 0.8 2.2 3 0 0 3 3 3 0 ETC complex I subunit conserved region Malate_synthase PF01274.22 AIM23872.1 - 5.2e-209 694.9 0.0 5.9e-209 694.7 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.14 AIM23872.1 - 0.003 16.7 0.0 0.0052 16.0 0.0 1.4 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family BTAD PF03704.17 AIM23872.1 - 3.7 8.0 6.1 0.51 10.8 0.2 2.5 3 0 0 3 3 3 0 Bacterial transcriptional activator domain HTS PF04204.16 AIM23873.1 - 6e-133 442.4 0.0 6.7e-133 442.2 0.0 1.0 1 0 0 1 1 1 1 Homoserine O-succinyltransferase Hexapep PF00132.24 AIM23875.1 - 2.6e-18 65.0 5.8 4.4e-07 29.4 1.0 4.1 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AIM23875.1 - 8.8e-08 31.8 4.9 0.0062 16.3 0.4 4.0 3 1 0 4 4 4 3 Hexapeptide repeat of succinyl-transferase Shikimate_dh_N PF08501.11 AIM23876.1 - 1.6e-23 82.7 0.0 2.9e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 AIM23876.1 - 1.7e-10 41.1 0.0 2.8e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase SDH_C PF18317.1 AIM23876.1 - 3.7e-10 39.4 1.4 3.7e-10 39.4 1.4 2.0 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain Sua5_yciO_yrdC PF01300.18 AIM23877.1 - 1.6e-43 148.3 0.0 1.7e-43 148.2 0.0 1.0 1 0 0 1 1 1 1 Telomere recombination zf-C4_Topoisom PF01396.19 AIM23878.1 - 1.4e-47 159.1 23.6 3e-16 58.9 1.4 4.1 4 0 0 4 4 4 3 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_2 PF13240.6 AIM23878.1 - 0.00041 20.0 12.4 0.65 9.8 0.1 5.2 5 0 0 5 5 5 2 zinc-ribbon domain zf-ribbon_3 PF13248.6 AIM23878.1 - 0.0011 18.3 15.0 0.26 10.8 0.1 5.4 6 0 0 6 6 6 2 zinc-ribbon domain Zn_Tnp_IS1 PF03811.13 AIM23878.1 - 0.004 16.8 16.9 0.03 14.0 0.2 4.5 4 1 0 4 4 4 2 InsA N-terminal domain PhnA_Zn_Ribbon PF08274.12 AIM23878.1 - 0.0055 16.6 5.3 0.22 11.5 0.0 3.6 3 3 0 3 3 2 1 PhnA Zinc-Ribbon Toprim_C_rpt PF13368.6 AIM23878.1 - 0.0059 16.6 0.0 2 8.5 0.0 2.7 2 1 1 3 3 3 1 Topoisomerase C-terminal repeat Zn-ribbon_8 PF09723.10 AIM23878.1 - 0.026 14.6 19.5 0.16 12.1 1.4 4.1 4 1 1 5 5 4 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 AIM23878.1 - 0.036 13.6 9.4 0.72 9.4 0.3 3.7 4 0 0 4 4 4 0 TFIIB zinc-binding DZR PF12773.7 AIM23878.1 - 0.051 13.6 22.4 1.8e+04 -4.2 22.4 4.1 1 1 0 1 1 0 0 Double zinc ribbon Auto_anti-p27 PF06677.12 AIM23878.1 - 0.12 12.5 16.8 4.3 7.6 1.0 4.4 3 1 2 5 5 5 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF1272 PF06906.11 AIM23878.1 - 0.14 12.2 13.3 1.9 8.6 0.1 4.5 4 1 1 5 5 5 0 Protein of unknown function (DUF1272) zf_UBZ PF18439.1 AIM23878.1 - 0.18 11.4 9.5 12 5.6 0.1 4.4 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-IS66 PF13005.7 AIM23878.1 - 0.18 12.2 11.5 17 5.9 0.1 4.5 4 1 1 5 5 5 0 zinc-finger binding domain of transposase IS66 RNA_POL_M_15KD PF02150.16 AIM23878.1 - 0.18 11.7 0.2 0.18 11.7 0.2 4.1 4 0 0 4 4 4 0 RNA polymerases M/15 Kd subunit zinc_ribbon_9 PF14369.6 AIM23878.1 - 0.22 11.8 0.4 0.22 11.8 0.4 4.7 4 1 0 4 4 3 0 zinc-ribbon PADR1 PF08063.12 AIM23878.1 - 0.24 11.2 17.4 2.4 8.0 0.5 4.1 4 2 0 4 4 4 0 PADR1 (NUC008) domain ADK_lid PF05191.14 AIM23878.1 - 0.58 10.2 11.8 2.2 8.3 0.0 4.3 4 0 0 4 4 4 0 Adenylate kinase, active site lid zf-ACC PF17848.1 AIM23878.1 - 1 9.5 10.2 25 5.1 0.2 3.8 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain zf-RRN7 PF11781.8 AIM23878.1 - 1.1 9.0 16.2 0.97 9.2 0.3 4.2 4 0 0 4 4 4 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zinc_ribbon_4 PF13717.6 AIM23878.1 - 1.7 8.6 12.0 8.8 6.3 0.1 4.4 5 0 0 5 5 5 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 AIM23878.1 - 1.9 8.5 19.4 1.8 8.6 5.4 3.7 2 1 1 3 3 3 0 zinc-ribbons Ogr_Delta PF04606.12 AIM23878.1 - 2.6 8.1 25.8 0.27 11.3 0.6 5.5 4 3 0 4 4 4 0 Ogr/Delta-like zinc finger zf-NADH-PPase PF09297.11 AIM23878.1 - 2.9 7.6 17.0 1.6 8.4 0.1 4.7 4 1 1 5 5 5 0 NADH pyrophosphatase zinc ribbon domain YacG PF03884.14 AIM23878.1 - 3.2 7.6 13.8 8.3 6.2 0.9 4.0 4 0 0 4 4 3 0 DNA gyrase inhibitor YacG zf-TFIIB PF13453.6 AIM23878.1 - 8.1 5.9 17.7 3.7 6.9 0.1 4.1 4 0 0 4 4 3 0 Transcription factor zinc-finger zf-Mss51 PF13824.6 AIM23878.1 - 8.4 6.6 13.1 19 5.4 4.0 3.8 3 1 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF494 PF04361.13 AIM23879.1 - 7.5e-60 201.2 2.4 8.4e-60 201.1 2.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF494) DNA_processg_A PF02481.15 AIM23880.1 - 2.1e-74 249.3 0.0 2.7e-74 248.9 0.0 1.1 1 0 0 1 1 1 1 DNA recombination-mediator protein A DprA_WH PF17782.1 AIM23880.1 - 2.3e-10 40.5 0.2 2.3e-10 40.5 0.2 2.1 3 0 0 3 3 3 1 DprA winged helix domain LDcluster4 PF18306.1 AIM23880.1 - 0.022 14.4 0.1 0.11 12.1 0.1 2.1 1 1 1 2 2 2 0 SLOG cluster4 family Pep_deformylase PF01327.21 AIM23881.1 - 1.5e-49 167.7 0.1 1.8e-49 167.4 0.1 1.1 1 0 0 1 1 1 1 Polypeptide deformylase Scytalone_dh PF02982.14 AIM23881.1 - 0.16 11.8 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Scytalone dehydratase Formyl_trans_N PF00551.19 AIM23882.1 - 2.4e-52 177.3 0.0 3.5e-52 176.8 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 AIM23882.1 - 4.8e-32 110.2 0.0 7.2e-32 109.6 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Methyltr_RsmB-F PF01189.17 AIM23883.1 - 1e-75 253.8 0.0 1.7e-75 253.1 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F NusB PF01029.18 AIM23883.1 - 1.5e-24 86.7 0.0 4.4e-24 85.2 0.0 1.8 2 0 0 2 2 2 1 NusB family Methyltransf_31 PF13847.6 AIM23883.1 - 4.6e-10 39.5 0.0 8.6e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AIM23883.1 - 5.4e-07 30.2 0.0 1.5e-06 28.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AIM23883.1 - 2.2e-06 27.3 0.0 4.9e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 AIM23883.1 - 9.2e-06 25.9 0.0 1.6e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_5 PF01795.19 AIM23883.1 - 2.3e-05 24.1 0.0 3.6e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 MraW methylase family Methyltr_RsmF_N PF17125.5 AIM23883.1 - 5.2e-05 23.7 0.0 0.00012 22.4 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF Cons_hypoth95 PF03602.15 AIM23883.1 - 0.0008 19.1 0.0 0.0025 17.5 0.0 1.7 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_33 PF10017.9 AIM23883.1 - 0.0037 16.5 0.0 0.0076 15.4 0.0 1.5 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_24 PF13578.6 AIM23883.1 - 0.0049 17.9 0.3 0.18 12.9 0.1 2.7 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AIM23883.1 - 0.0099 16.5 0.0 0.025 15.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AIM23883.1 - 0.013 16.2 0.0 0.044 14.5 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.10 AIM23883.1 - 0.021 14.4 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.7 AIM23883.1 - 0.056 13.4 0.0 0.09 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF4089 PF13318.6 AIM23883.1 - 0.1 13.1 1.0 0.59 10.6 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4089) Met_10 PF02475.16 AIM23883.1 - 0.13 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Ubie_methyltran PF01209.18 AIM23883.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family LysM PF01476.20 AIM23883.1 - 0.2 11.7 0.3 0.65 10.1 0.3 1.8 1 0 0 1 1 1 0 LysM domain TrkA_N PF02254.18 AIM23884.1 - 1.3e-58 196.3 4.1 2.6e-30 105.1 0.0 2.4 2 0 0 2 2 2 2 TrkA-N domain TrkA_C PF02080.21 AIM23884.1 - 5.3e-25 87.0 2.4 1.4e-11 44.1 0.0 3.8 4 0 0 4 4 3 2 TrkA-C domain NAD_binding_7 PF13241.6 AIM23884.1 - 1.8e-12 47.6 4.4 6.1e-05 23.4 0.2 3.4 2 1 1 3 3 3 2 Putative NAD(P)-binding F420_oxidored PF03807.17 AIM23884.1 - 5.8e-11 42.8 5.6 9.5e-05 22.9 0.5 3.9 3 2 1 4 4 4 2 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 AIM23884.1 - 3.3e-10 40.1 3.6 9.5e-06 25.7 0.7 2.8 2 1 1 3 3 3 2 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 AIM23884.1 - 1.6e-09 38.1 2.1 0.00028 21.2 0.3 2.5 2 0 0 2 2 2 2 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 AIM23884.1 - 2.7e-09 36.8 0.8 0.0036 17.0 0.0 3.1 3 1 0 3 3 3 2 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 AIM23884.1 - 1.5e-06 28.2 3.3 0.01 15.7 0.7 2.4 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 AIM23884.1 - 2.6e-06 27.4 5.5 0.0013 18.7 0.9 2.6 2 1 0 2 2 2 2 NAD(P)H-binding AlaDh_PNT_C PF01262.21 AIM23884.1 - 2.9e-06 26.7 7.9 0.0082 15.5 0.2 3.0 2 1 1 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 AIM23884.1 - 4.9e-06 26.8 4.6 0.043 14.0 0.6 3.2 4 0 0 4 4 3 2 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox_2 PF07992.14 AIM23884.1 - 1e-05 24.9 0.2 0.0025 17.1 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AIM23884.1 - 1.5e-05 25.4 2.0 0.19 12.3 0.1 3.1 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 AIM23884.1 - 4.2e-05 23.2 0.6 0.0039 16.8 0.0 2.8 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.23 AIM23884.1 - 6.7e-05 22.9 1.1 0.13 12.3 0.0 3.4 2 2 1 3 3 3 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF1188 PF06690.11 AIM23884.1 - 0.00038 20.1 0.1 0.34 10.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1188) GFO_IDH_MocA PF01408.22 AIM23884.1 - 0.00053 20.8 0.6 0.16 12.8 0.2 2.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Epimerase PF01370.21 AIM23884.1 - 0.0011 18.5 1.4 0.61 9.5 0.1 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_8 PF13450.6 AIM23884.1 - 0.0014 18.8 0.1 1 9.7 0.0 2.9 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain XdhC_C PF13478.6 AIM23884.1 - 0.0038 17.7 0.8 1.2 9.6 0.0 2.5 2 1 0 2 2 2 1 XdhC Rossmann domain DAO PF01266.24 AIM23884.1 - 0.0097 15.5 3.0 0.11 12.0 0.2 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase ThiF PF00899.21 AIM23884.1 - 0.03 13.7 1.1 0.64 9.3 0.2 2.5 2 0 0 2 2 2 0 ThiF family Pyr_redox_3 PF13738.6 AIM23884.1 - 0.057 12.7 0.3 0.89 8.7 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 AIM23884.1 - 0.06 12.4 1.7 1.6 7.7 0.2 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 AIM23884.1 - 0.087 12.1 0.7 2.4 7.3 0.2 2.5 2 1 0 2 2 2 0 FAD binding domain K_oxygenase PF13434.6 AIM23884.1 - 0.088 11.9 0.2 2 7.4 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) MscL PF01741.18 AIM23885.1 - 1.7e-47 160.7 0.8 1.9e-47 160.5 0.8 1.0 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL DUF3487 PF11990.8 AIM23885.1 - 0.14 12.0 3.8 1.2 9.0 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3487) ArfA PF03889.13 AIM23886.1 - 7.9e-26 89.3 1.7 1e-25 89.0 1.7 1.1 1 0 0 1 1 1 1 Alternative ribosome-rescue factor A MerR_1 PF13411.6 AIM23887.1 - 3.4e-21 75.1 0.3 5.7e-21 74.4 0.3 1.3 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR-DNA-bind PF09278.11 AIM23887.1 - 4e-19 68.9 1.9 5.9e-19 68.4 1.9 1.3 1 0 0 1 1 1 1 MerR, DNA binding MerR PF00376.23 AIM23887.1 - 2.9e-14 52.5 0.0 6.5e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 MerR family regulatory protein DUF1836 PF08876.11 AIM23887.1 - 0.031 14.3 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1836) PDCD7 PF16021.5 AIM23887.1 - 0.08 12.1 0.2 0.12 11.5 0.2 1.2 1 0 0 1 1 1 0 Programmed cell death protein 7 CPSase_L_D3 PF02787.19 AIM23887.1 - 0.1 12.9 0.1 0.79 10.1 0.1 2.4 1 1 1 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain DUF1992 PF09350.10 AIM23888.1 - 3.2e-23 81.6 0.0 5.3e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) Ribosomal_L17 PF01196.19 AIM23889.1 - 8.8e-35 119.5 0.0 1.1e-34 119.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L17 RNA_pol_L PF01193.24 AIM23890.1 - 2.5e-24 84.5 0.0 4.1e-24 83.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_A_CTD PF03118.15 AIM23890.1 - 4.5e-24 84.0 0.1 8e-24 83.2 0.1 1.4 1 0 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain RNA_pol_A_bac PF01000.26 AIM23890.1 - 8.2e-24 84.1 0.2 1.9e-23 83.0 0.1 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L_2 PF13656.6 AIM23890.1 - 0.00012 21.8 0.0 0.61 9.9 0.0 2.6 2 0 0 2 2 2 2 RNA polymerase Rpb3/Rpb11 dimerisation domain YjbH PF06082.11 AIM23890.1 - 0.27 10.0 0.1 0.41 9.4 0.1 1.2 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH Ribosomal_S4 PF00163.19 AIM23891.1 - 9e-33 113.1 4.3 1e-32 112.9 3.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 AIM23891.1 - 1.6e-18 66.2 0.3 3.1e-18 65.2 0.3 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 AIM23891.1 - 0.021 14.6 0.2 0.045 13.6 0.2 1.5 1 0 0 1 1 1 0 S4 domain Ribosomal_S11 PF00411.19 AIM23892.1 - 1.8e-54 182.8 0.8 2.1e-54 182.6 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S11 Ribosomal_S13 PF00416.22 AIM23893.1 - 2.9e-35 121.5 6.5 1.3e-33 116.1 6.5 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 AIM23893.1 - 0.0005 18.9 0.0 0.00053 18.9 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DUF5053 PF16476.5 AIM23893.1 - 0.17 11.6 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5053) Ribosomal_L36 PF00444.18 AIM23894.1 - 1.8e-20 72.9 10.6 1.9e-20 72.8 10.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L36 SecY PF00344.20 AIM23895.1 - 1e-118 396.1 18.8 1.3e-118 395.8 18.8 1.1 1 0 0 1 1 1 1 SecY translocase TssN PF17555.2 AIM23895.1 - 4.9 6.5 10.3 0.15 11.4 2.7 2.2 2 0 0 2 2 2 0 Type VI secretion system, TssN Ribosomal_L27A PF00828.19 AIM23896.1 - 5.6e-31 107.9 1.7 7.1e-31 107.5 1.7 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_L18 PF17135.4 AIM23896.1 - 0.074 12.4 0.2 0.11 11.9 0.2 1.3 1 0 0 1 1 1 0 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L30 PF00327.20 AIM23897.1 - 6.4e-20 70.8 0.2 7.3e-20 70.6 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_S5_C PF03719.15 AIM23898.1 - 1e-30 105.0 0.9 1e-30 105.0 0.9 1.6 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 AIM23898.1 - 1.1e-29 102.2 2.8 1.1e-29 102.2 2.8 1.8 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_L6 PF00347.23 AIM23899.1 - 1.9e-41 140.6 0.1 4e-20 72.3 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Ribosomal_S8 PF00410.19 AIM23900.1 - 1.9e-48 163.6 0.1 2.1e-48 163.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S14 PF00253.21 AIM23901.1 - 2.9e-25 87.8 1.2 4.1e-25 87.3 1.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Ribosomal_L5_C PF00673.21 AIM23902.1 - 4.8e-41 138.9 0.0 7.4e-41 138.2 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 AIM23902.1 - 6.2e-29 100.1 0.3 1.1e-28 99.3 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 DUF2862 PF11061.8 AIM23902.1 - 0.054 13.3 0.0 0.24 11.2 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2862) ribosomal_L24 PF17136.4 AIM23903.1 - 8.1e-23 80.6 0.1 8.1e-23 80.6 0.1 1.5 2 0 0 2 2 2 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 AIM23903.1 - 5.6e-05 23.0 4.4 0.00013 21.8 4.4 1.7 1 0 0 1 1 1 1 KOW motif Ribosomal_L14 PF00238.19 AIM23904.1 - 6.8e-55 184.4 1.1 7.5e-55 184.2 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Gp58 PF07902.11 AIM23904.1 - 0.066 11.5 0.1 0.078 11.3 0.1 1.0 1 0 0 1 1 1 0 gp58-like protein Ribosomal_S17 PF00366.20 AIM23905.1 - 5.9e-34 116.0 1.8 7e-34 115.8 1.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_L29 PF00831.23 AIM23906.1 - 4.8e-23 80.9 7.4 5.3e-23 80.8 7.4 1.0 1 0 0 1 1 1 1 Ribosomal L29 protein MRP-L47 PF06984.13 AIM23906.1 - 0.00073 19.6 2.5 0.00088 19.4 2.5 1.1 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L16 PF00252.18 AIM23907.1 - 3e-47 159.9 0.7 3.4e-47 159.8 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DUF982 PF06169.12 AIM23907.1 - 0.075 13.1 2.0 9 6.4 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF982) Ribosomal_S3_C PF00189.20 AIM23908.1 - 1.2e-41 141.1 0.9 2.1e-41 140.3 0.9 1.4 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 AIM23908.1 - 2.8e-19 68.7 3.3 6.4e-19 67.6 3.3 1.6 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 AIM23908.1 - 0.00035 20.4 0.2 0.00085 19.1 0.2 1.7 1 1 0 1 1 1 1 KH domain MRP-S24 PF14955.6 AIM23908.1 - 0.025 14.5 0.0 0.041 13.8 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S24 Ribosomal_L22 PF00237.19 AIM23909.1 - 2.1e-34 117.9 1.6 2.3e-34 117.7 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF733 PF05306.11 AIM23909.1 - 0.069 13.5 0.3 0.077 13.3 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF733) Ribosomal_S19 PF00203.21 AIM23910.1 - 1.3e-35 121.1 0.0 1.5e-35 120.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19 Oest_recep PF02159.15 AIM23910.1 - 0.21 12.0 0.0 0.25 11.8 0.0 1.1 1 0 0 1 1 1 0 Oestrogen receptor Ribosomal_L2_C PF03947.18 AIM23911.1 - 4.1e-55 185.4 3.6 6.7e-55 184.7 3.6 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 AIM23911.1 - 1.9e-34 117.5 0.7 4.2e-34 116.3 0.7 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Ribosomal_L23 PF00276.20 AIM23912.1 - 3.7e-32 110.5 3.5 4.3e-32 110.3 3.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L23 ubiquitin PF00240.23 AIM23912.1 - 0.00083 19.1 0.2 0.0013 18.5 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin family WHEP-TRS PF00458.20 AIM23912.1 - 0.051 13.7 1.9 0.13 12.5 1.9 1.7 1 0 0 1 1 1 0 WHEP-TRS domain P16-Arc PF04699.14 AIM23912.1 - 0.052 14.0 0.7 0.069 13.6 0.7 1.1 1 0 0 1 1 1 0 ARP2/3 complex 16 kDa subunit (p16-Arc) DnaJ PF00226.31 AIM23912.1 - 0.15 12.2 0.4 0.34 11.1 0.1 1.7 2 0 0 2 2 2 0 DnaJ domain Ribosomal_L4 PF00573.22 AIM23913.1 - 4.4e-64 215.7 1.4 5e-64 215.5 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_L3 PF00297.22 AIM23914.1 - 6.9e-13 48.3 8.7 1.6e-12 47.1 6.7 2.3 1 1 1 2 2 2 2 Ribosomal protein L3 Ribosomal_S10 PF00338.22 AIM23915.1 - 2.1e-35 120.9 0.1 2.3e-35 120.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Ferritin PF00210.24 AIM23916.1 - 2.6e-39 134.4 4.4 3e-39 134.2 4.4 1.0 1 0 0 1 1 1 1 Ferritin-like domain COQ7 PF03232.13 AIM23916.1 - 0.08 12.7 0.4 0.12 12.2 0.0 1.4 2 0 0 2 2 2 0 Ubiquinone biosynthesis protein COQ7 Fer2_BFD PF04324.15 AIM23917.1 - 4.4e-15 55.7 1.5 5.2e-15 55.5 1.5 1.1 1 0 0 1 1 1 1 BFD-like [2Fe-2S] binding domain GTP_EFTU PF00009.27 AIM23918.1 - 1.3e-66 223.9 0.1 2e-66 223.3 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 AIM23918.1 - 1.9e-44 150.3 0.0 4.2e-44 149.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 AIM23918.1 - 4.4e-34 116.4 0.0 9.6e-34 115.3 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 AIM23918.1 - 1.1e-28 99.0 0.0 3e-28 97.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 AIM23918.1 - 2.5e-16 59.8 0.2 6.5e-16 58.5 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 AIM23918.1 - 1.4e-06 28.1 0.0 3.3e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Slu7 PF11708.8 AIM23918.1 - 0.064 13.0 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor Ribosomal_S7 PF00177.21 AIM23919.1 - 2.1e-65 218.9 2.1 2.3e-65 218.8 2.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e ArgJ PF01960.18 AIM23919.1 - 0.08 11.6 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 ArgJ family Ribosom_S12_S23 PF00164.25 AIM23920.1 - 6.1e-43 145.1 0.9 7.2e-43 144.8 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S12 PF17487.2 AIM23920.1 - 0.1 13.3 0.0 0.19 12.5 0.0 1.4 1 1 0 1 1 1 0 Ribosomal protein S12 DsrH PF04077.12 AIM23921.1 - 1.9e-26 92.0 0.0 2.1e-26 91.8 0.0 1.0 1 0 0 1 1 1 1 DsrH like protein DrsE PF02635.15 AIM23922.1 - 5.8e-25 87.9 0.0 6.4e-25 87.8 0.0 1.0 1 0 0 1 1 1 1 DsrE/DsrF-like family Ribosomal_L5 PF00281.19 AIM23922.1 - 0.032 14.6 0.0 0.064 13.6 0.0 1.5 2 0 0 2 2 2 0 Ribosomal protein L5 DrsE PF02635.15 AIM23923.1 - 9.8e-29 100.1 0.1 1.2e-28 99.8 0.1 1.0 1 0 0 1 1 1 1 DsrE/DsrF-like family PAS_6 PF08348.11 AIM23924.1 - 1.1e-36 125.2 0.0 1.9e-36 124.4 0.0 1.4 1 0 0 1 1 1 1 YheO-like PAS domain HTH_22 PF13309.6 AIM23924.1 - 1.1e-18 67.1 0.3 1.8e-18 66.4 0.3 1.4 1 0 0 1 1 1 1 HTH domain HTH_23 PF13384.6 AIM23924.1 - 1.2e-05 25.0 0.0 2.6e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.15 AIM23924.1 - 0.00025 21.1 0.1 0.0008 19.4 0.1 1.9 2 1 0 2 2 2 1 Helix-turn-helix domain of resolvase DUF658 PF04936.12 AIM23924.1 - 0.0038 17.0 0.1 0.0059 16.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF658) HTH_17 PF12728.7 AIM23924.1 - 0.0047 17.1 0.0 0.0098 16.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_10 PF04967.12 AIM23924.1 - 0.018 14.8 0.0 0.045 13.5 0.0 1.6 1 0 0 1 1 1 0 HTH DNA binding domain dCache_1 PF02743.18 AIM23924.1 - 0.021 14.6 0.1 0.042 13.6 0.0 1.6 2 0 0 2 2 2 0 Cache domain HTH_29 PF13551.6 AIM23924.1 - 0.032 14.2 0.0 0.067 13.2 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix Phage_CI_repr PF07022.13 AIM23924.1 - 0.054 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain GerE PF00196.19 AIM23924.1 - 0.073 12.6 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family DUF3791 PF12668.7 AIM23924.1 - 0.11 12.5 0.1 0.41 10.7 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3791) MerR PF00376.23 AIM23924.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 MerR family regulatory protein FKBP_C PF00254.28 AIM23925.1 - 6.4e-31 106.5 0.1 3.8e-28 97.7 0.0 2.5 2 1 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N PF01346.18 AIM23925.1 - 5.4e-22 78.6 7.5 1.2e-21 77.4 7.5 1.6 1 0 0 1 1 1 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase DUF4827 PF16109.5 AIM23925.1 - 0.038 14.0 0.2 1.1 9.3 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4827) DUF3811 PF11656.8 AIM23925.1 - 2.2 8.8 5.7 0.77 10.2 2.2 2.0 2 0 0 2 2 2 0 YjbD family (DUF3811) SlyX PF04102.12 AIM23926.1 - 9.1e-23 80.7 7.4 1e-22 80.5 7.4 1.0 1 0 0 1 1 1 1 SlyX MscS_porin PF12795.7 AIM23926.1 - 0.0016 18.0 9.4 0.0019 17.8 9.4 1.0 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain Mt_ATP-synt_D PF05873.12 AIM23926.1 - 0.044 13.6 0.3 0.061 13.2 0.3 1.3 1 1 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) SF1-HH PF16275.5 AIM23926.1 - 0.054 13.8 2.8 0.078 13.3 2.7 1.3 1 1 0 1 1 1 0 Splicing factor 1 helix-hairpin domain Atg14 PF10186.9 AIM23926.1 - 0.058 12.5 2.3 0.069 12.2 2.3 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1192 PF06698.11 AIM23926.1 - 0.064 13.3 0.8 0.096 12.8 0.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) DUF641 PF04859.12 AIM23926.1 - 0.15 12.4 3.8 0.17 12.2 3.8 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) TMF_DNA_bd PF12329.8 AIM23926.1 - 0.16 12.0 7.7 0.69 9.9 7.7 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF16 PF01519.16 AIM23926.1 - 0.19 12.3 3.5 0.24 11.9 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF16 FKBP_C PF00254.28 AIM23927.1 - 4.5e-09 36.5 0.0 6.4e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase SelP_N PF04592.14 AIM23927.1 - 5.2 6.4 11.2 8.2 5.7 11.2 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF2387 PF09526.10 AIM23928.1 - 6.4e-09 35.8 0.6 7.2e-09 35.7 0.6 1.1 1 0 0 1 1 1 1 Probable metal-binding protein (DUF2387) Na_H_Exchanger PF00999.21 AIM23929.1 - 3.5e-68 230.2 45.2 4.6e-68 229.8 45.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TrkA_N PF02254.18 AIM23929.1 - 2e-24 86.1 0.1 3.6e-24 85.2 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain 2-Hacid_dh_C PF02826.19 AIM23929.1 - 0.044 13.1 0.0 0.086 12.2 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 AIM23929.1 - 0.1 12.7 0.1 0.27 11.3 0.1 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 AIM23929.1 - 0.1 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Flavodoxin_2 PF02525.17 AIM23930.1 - 1.4e-41 142.4 0.0 1.6e-41 142.2 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 AIM23930.1 - 8.1e-05 22.4 0.0 0.00017 21.4 0.0 1.5 1 1 0 1 1 1 1 NADPH-dependent FMN reductase ABC_tran PF00005.27 AIM23931.1 - 8e-51 172.2 4.9 2.6e-24 86.3 0.0 4.0 4 0 0 4 4 4 2 ABC transporter ABC_tran_Xtn PF12848.7 AIM23931.1 - 4.7e-28 97.1 5.0 4.7e-28 97.1 5.0 3.1 2 1 1 3 3 2 1 ABC transporter AAA_21 PF13304.6 AIM23931.1 - 7.3e-15 55.6 12.1 0.0041 17.0 0.8 4.5 4 1 1 5 5 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIM23931.1 - 2.2e-07 30.5 1.6 0.073 12.5 0.0 4.2 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 AIM23931.1 - 7e-07 29.3 0.5 0.034 14.2 0.0 3.1 3 1 0 3 3 2 2 50S ribosome-binding GTPase ABC_tran_CTD PF16326.5 AIM23931.1 - 2.6e-06 27.6 12.9 2.6e-06 27.6 12.9 3.4 3 0 0 3 3 3 1 ABC transporter C-terminal domain AAA_29 PF13555.6 AIM23931.1 - 9.6e-06 25.3 1.8 0.086 12.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 AIM23931.1 - 2.1e-05 25.0 10.9 0.00019 21.8 0.0 3.4 3 1 0 4 4 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 AIM23931.1 - 2.2e-05 24.4 2.5 0.12 12.3 0.2 2.8 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 AIM23931.1 - 0.00059 20.4 1.3 2.1 8.9 0.0 3.4 4 0 0 4 4 2 2 AAA domain AAA_25 PF13481.6 AIM23931.1 - 0.00086 18.9 3.7 0.045 13.3 0.0 3.9 4 0 0 4 4 4 1 AAA domain MeaB PF03308.16 AIM23931.1 - 0.0011 18.0 6.4 0.11 11.5 0.2 2.8 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 AIM23931.1 - 0.0023 18.2 0.6 2.9 8.1 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.6 AIM23931.1 - 0.0031 17.2 0.6 2.7 7.7 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 AIM23931.1 - 0.0033 17.7 0.4 3.8 7.8 0.0 3.6 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 AIM23931.1 - 0.0051 17.2 0.8 3.1 8.2 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA PF00004.29 AIM23931.1 - 0.0069 16.8 0.0 4.6 7.7 0.0 2.9 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 AIM23931.1 - 0.0092 15.2 1.5 3.2 6.8 0.1 3.1 2 1 1 3 3 3 1 Protein of unknown function (DUF815) NACHT PF05729.12 AIM23931.1 - 0.014 15.3 5.7 0.96 9.3 0.2 3.5 3 0 0 3 3 3 0 NACHT domain AAA_24 PF13479.6 AIM23931.1 - 0.016 15.0 2.0 4.1 7.1 0.2 3.0 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 AIM23931.1 - 0.016 14.5 4.4 0.54 9.5 0.5 2.9 2 1 0 2 2 2 0 KAP family P-loop domain AAA_15 PF13175.6 AIM23931.1 - 0.021 14.5 12.8 0.1 12.3 0.3 4.4 5 0 0 5 5 5 0 AAA ATPase domain NB-ARC PF00931.22 AIM23931.1 - 0.023 13.9 0.5 2.2 7.4 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain ATP-synt_ab PF00006.25 AIM23931.1 - 0.023 14.3 0.8 0.63 9.7 0.1 2.4 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain PduV-EutP PF10662.9 AIM23931.1 - 0.095 12.4 2.2 4.4 7.1 0.3 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 AIM23931.1 - 0.12 11.9 0.1 6.7 6.2 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B SbcCD_C PF13558.6 AIM23931.1 - 0.14 12.4 1.7 2.9 8.2 0.1 3.6 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit NTPase_1 PF03266.15 AIM23931.1 - 0.15 11.9 1.3 9.9 6.0 0.1 2.5 2 0 0 2 2 2 0 NTPase AAA_13 PF13166.6 AIM23931.1 - 0.23 10.1 15.6 1.1 7.8 2.9 3.9 4 0 0 4 4 4 0 AAA domain MobB PF03205.14 AIM23931.1 - 0.24 11.3 1.5 14 5.6 0.2 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Roc PF08477.13 AIM23931.1 - 0.38 11.0 2.1 24 5.2 0.4 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 AIM23931.1 - 0.42 10.6 2.9 9.5 6.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Exonuc_VII_L PF02601.15 AIM23931.1 - 1.4 8.5 11.4 2.3 7.7 0.3 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF2730 PF10805.8 AIM23931.1 - 1.4 9.1 7.0 0.16 12.1 0.9 2.6 2 1 1 3 3 2 0 Protein of unknown function (DUF2730) Zeta_toxin PF06414.12 AIM23931.1 - 2.6 7.3 9.6 1.5 8.1 0.1 3.1 4 0 0 4 4 4 0 Zeta toxin AAA_33 PF13671.6 AIM23931.1 - 4.8 7.3 8.7 24 5.1 0.2 3.9 4 0 0 4 4 4 0 AAA domain FliD_N PF02465.18 AIM23931.1 - 5.9 7.7 18.0 0.12 13.0 5.5 3.2 2 2 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF87 PF01935.17 AIM23931.1 - 9.1 6.3 12.4 3 7.9 0.1 3.6 4 0 0 4 4 4 0 Helicase HerA, central domain TauD PF02668.16 AIM23932.1 - 3.1e-67 227.2 3.5 3.5e-67 227.0 3.5 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family BPD_transp_1 PF00528.22 AIM23933.1 - 3.3e-24 85.6 15.4 3.3e-24 85.6 15.4 2.0 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component HEAT_PBS PF03130.16 AIM23933.1 - 0.0053 17.3 1.9 0.079 13.7 0.3 3.1 2 0 0 2 2 2 1 PBS lyase HEAT-like repeat Bap31 PF05529.12 AIM23933.1 - 0.039 13.8 0.3 0.57 10.0 0.0 2.4 2 1 1 3 3 3 0 Bap31/Bap29 transmembrane region DUF4407 PF14362.6 AIM23933.1 - 0.16 11.3 1.0 0.3 10.4 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TNFR_16_TM PF18422.1 AIM23933.1 - 6.4 6.8 5.7 22 5.1 1.5 2.7 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain ABC_tran PF00005.27 AIM23934.1 - 2.3e-32 112.4 0.0 3.1e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AIM23934.1 - 3.4e-07 30.4 0.1 0.016 15.0 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AIM23934.1 - 8.1e-06 26.3 0.2 1.2e-05 25.7 0.2 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 AIM23934.1 - 1.6e-05 25.2 0.1 0.0033 17.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 AIM23934.1 - 6.1e-05 23.0 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 AIM23934.1 - 0.00013 22.2 0.2 0.00067 19.9 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AIM23934.1 - 0.00074 19.3 0.3 0.0044 16.8 0.3 2.0 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 AIM23934.1 - 0.0014 19.1 0.0 0.0055 17.1 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 AIM23934.1 - 0.0057 16.9 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 AIM23934.1 - 0.0079 16.1 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain NACHT PF05729.12 AIM23934.1 - 0.0085 16.0 0.2 0.025 14.5 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_23 PF13476.6 AIM23934.1 - 0.0099 16.4 0.0 0.016 15.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 AIM23934.1 - 0.011 14.9 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase_2 PF01637.18 AIM23934.1 - 0.019 14.9 0.1 0.059 13.3 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 AIM23934.1 - 0.021 15.0 0.4 0.27 11.4 0.2 2.2 2 1 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 AIM23934.1 - 0.027 14.1 0.1 0.25 11.0 0.1 2.0 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.6 AIM23934.1 - 0.035 13.7 0.1 0.1 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 AIM23934.1 - 0.048 13.4 0.0 0.37 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 AIM23934.1 - 0.049 13.4 0.1 0.095 12.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 AIM23934.1 - 0.051 13.0 0.0 9.6 5.6 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 AIM23934.1 - 0.066 12.0 0.0 1.2 7.8 0.0 2.0 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_5 PF07728.14 AIM23934.1 - 0.082 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 AIM23934.1 - 0.089 13.2 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 AIM23934.1 - 0.094 12.4 0.1 0.61 9.8 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_14 PF13173.6 AIM23934.1 - 0.096 12.7 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 AIM23934.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 AIM23934.1 - 0.12 12.1 0.1 0.24 11.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 AIM23934.1 - 0.17 12.2 0.2 0.53 10.6 0.0 1.8 3 0 0 3 3 1 0 AAA domain DLIC PF05783.11 AIM23934.1 - 0.22 10.3 0.0 0.32 9.8 0.0 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) OpuAC PF04069.12 AIM23935.1 - 2.3e-22 79.8 1.3 3.2e-22 79.4 1.3 1.2 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system NMT1 PF09084.11 AIM23935.1 - 5.7e-20 72.2 0.0 7.3e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 AIM23935.1 - 6.8e-19 68.6 2.6 1.5e-18 67.4 2.6 1.5 1 1 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.7 AIM23935.1 - 1.8e-09 37.5 0.4 2.7e-09 37.0 0.4 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 AIM23935.1 - 3e-06 26.8 0.1 0.00015 21.2 0.0 2.6 1 1 2 3 3 3 2 Bacterial extracellular solute-binding proteins, family 3 KN17_SH3 PF18131.1 AIM23935.1 - 0.12 12.5 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 KN17 SH3-like C-terminal domain PhzC-PhzF PF02567.16 AIM23936.1 - 2.9e-43 148.4 0.0 4.1e-43 147.9 0.0 1.2 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein LysE PF01810.18 AIM23937.1 - 7.2e-17 61.5 19.5 9e-17 61.2 19.5 1.1 1 0 0 1 1 1 1 LysE type translocator Abhydrolase_1 PF00561.20 AIM23938.1 - 8.3e-18 65.0 0.0 1.1e-17 64.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AIM23938.1 - 9.6e-09 34.9 0.0 2.2e-08 33.7 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF2048 PF09752.9 AIM23938.1 - 0.22 10.6 0.0 5.6 6.0 0.0 2.2 2 0 0 2 2 2 0 Abhydrolase domain containing 18 UPF0270 PF06794.12 AIM23939.1 - 1.9e-35 120.7 0.1 2.1e-35 120.6 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0270) HU-CCDC81_bac_2 PF18175.1 AIM23939.1 - 0.0022 17.8 0.0 0.0031 17.3 0.0 1.2 1 0 0 1 1 1 1 CCDC81-like prokaryotic HU domain 2 PRK PF00485.18 AIM23940.1 - 2.1e-73 246.3 0.0 2.5e-73 246.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family APS_kinase PF01583.20 AIM23940.1 - 0.022 14.6 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Zeta_toxin PF06414.12 AIM23940.1 - 0.17 11.2 0.0 0.51 9.6 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin OsmC PF02566.19 AIM23941.1 - 1.2e-18 67.5 0.1 1.5e-18 67.1 0.1 1.1 1 0 0 1 1 1 1 OsmC-like protein cNMP_binding PF00027.29 AIM23942.1 - 3.5e-24 84.7 0.0 5.4e-24 84.1 0.0 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HTH_Crp_2 PF13545.6 AIM23942.1 - 2.6e-14 52.9 0.1 2.2e-13 50.0 0.0 2.1 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain Crp PF00325.20 AIM23942.1 - 4.4e-09 35.8 0.1 9.2e-09 34.8 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, crp family MarR_2 PF12802.7 AIM23942.1 - 0.00048 20.0 0.1 0.0012 18.7 0.0 1.6 2 0 0 2 2 1 1 MarR family HTH_23 PF13384.6 AIM23942.1 - 0.00063 19.5 0.0 0.0014 18.4 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_36 PF13730.6 AIM23942.1 - 0.0013 18.6 0.0 0.0068 16.3 0.0 2.2 3 0 0 3 3 3 1 Helix-turn-helix domain RepL PF05732.11 AIM23942.1 - 0.0022 17.5 0.1 0.16 11.4 0.1 2.2 2 0 0 2 2 2 1 Firmicute plasmid replication protein (RepL) MarR PF01047.22 AIM23942.1 - 0.007 16.3 0.1 0.029 14.3 0.1 2.0 2 0 0 2 2 2 1 MarR family HTH_24 PF13412.6 AIM23942.1 - 0.0092 15.5 0.2 0.023 14.2 0.2 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.16 AIM23942.1 - 0.017 14.6 0.2 0.057 12.9 0.2 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_7 PF02796.15 AIM23942.1 - 0.072 13.2 0.1 0.23 11.5 0.1 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_11 PF08279.12 AIM23942.1 - 0.12 12.3 0.4 0.24 11.4 0.1 1.7 2 0 0 2 2 2 0 HTH domain DUF4868 PF16162.5 AIM23942.1 - 0.13 12.2 0.0 0.31 10.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4868) Asp1 PF16993.5 AIM23942.1 - 0.14 11.4 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Accessory Sec system protein Asp1 RPA_C PF08784.11 AIM23942.1 - 0.15 12.7 0.1 0.31 11.7 0.1 1.5 1 0 0 1 1 1 0 Replication protein A C terminal FUSC-like PF12805.7 AIM23943.1 - 4.3e-62 209.8 8.4 4.3e-62 209.8 8.4 2.5 3 0 0 3 3 3 1 FUSC-like inner membrane protein yccS FUSC_2 PF13515.6 AIM23943.1 - 5.3e-21 75.1 7.4 5.3e-21 75.1 7.4 2.4 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.12 AIM23943.1 - 2.9e-05 22.8 7.4 2.9e-05 22.8 7.4 3.0 2 1 0 2 2 2 1 Fusaric acid resistance protein family Aminotran_3 PF00202.21 AIM23944.1 - 4.8e-133 443.8 0.1 6e-133 443.4 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 AIM23944.1 - 0.0033 16.6 0.0 0.0048 16.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 AIM23944.1 - 0.094 12.0 0.0 0.24 10.6 0.0 1.6 2 0 0 2 2 2 0 Beta-eliminating lyase GATase PF00117.28 AIM23945.1 - 5.3e-54 182.9 0.0 5.9e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AIM23945.1 - 6.8e-09 35.8 0.1 7.9e-08 32.3 0.1 2.0 1 1 0 1 1 1 1 Peptidase C26 DUF853 PF05872.12 AIM23946.1 - 1.3e-232 772.9 1.2 1.5e-232 772.7 1.2 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) AAA_10 PF12846.7 AIM23946.1 - 4.3e-07 29.2 0.0 0.00053 19.0 0.0 2.2 2 0 0 2 2 2 2 AAA-like domain AAA_22 PF13401.6 AIM23946.1 - 7.2e-06 26.3 0.2 0.0018 18.6 0.1 2.4 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 AIM23946.1 - 2.8e-05 24.3 0.0 4.9e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Helicase HerA, central domain ResIII PF04851.15 AIM23946.1 - 4.5e-05 23.5 0.1 0.0069 16.4 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit FtsK_SpoIIIE PF01580.18 AIM23946.1 - 0.00011 21.6 0.1 0.0036 16.7 0.1 2.7 3 0 0 3 3 3 1 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.9 AIM23946.1 - 0.00034 19.6 0.1 0.001 18.1 0.1 1.8 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain DUF2075 PF09848.9 AIM23946.1 - 0.00086 18.6 0.1 0.53 9.5 0.1 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 AIM23946.1 - 0.0016 18.8 1.7 0.13 12.6 1.3 2.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 AIM23946.1 - 0.0043 17.4 0.0 0.031 14.6 0.0 2.4 3 0 0 3 3 3 1 AAA domain Zot PF05707.12 AIM23946.1 - 0.0054 16.4 0.0 0.043 13.4 0.0 2.1 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA PF00004.29 AIM23946.1 - 0.0071 16.8 0.0 2.7 8.4 0.1 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 AIM23946.1 - 0.013 15.2 1.9 0.02 14.6 0.1 2.2 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 AIM23946.1 - 0.017 14.7 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region T2SSE PF00437.20 AIM23946.1 - 0.023 13.7 0.0 0.042 12.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.6 AIM23946.1 - 0.049 13.9 0.1 0.098 12.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 AIM23946.1 - 0.054 13.1 0.2 0.11 12.1 0.2 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_25 PF13481.6 AIM23946.1 - 0.081 12.5 0.0 0.28 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 AIM23946.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain HrpJ PF07201.11 AIM23947.1 - 0.0034 17.7 0.7 0.0046 17.3 0.6 1.3 1 1 0 1 1 1 1 HrpJ-like domain Nbs1_C PF08599.10 AIM23947.1 - 0.015 15.4 1.6 0.032 14.4 1.2 1.7 1 1 0 1 1 1 0 DNA damage repair protein Nbs1 RHH_1 PF01402.21 AIM23947.1 - 0.046 13.7 0.3 0.046 13.7 0.3 2.1 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family RelB PF04221.12 AIM23947.1 - 0.068 13.1 0.1 0.076 13.0 0.1 1.4 1 1 0 1 1 1 0 RelB antitoxin Trns_repr_metal PF02583.17 AIM23947.1 - 0.09 13.2 0.1 0.12 12.8 0.1 1.2 1 0 0 1 1 1 0 Metal-sensitive transcriptional repressor ParE_toxin PF05016.15 AIM23948.1 - 1.4e-13 51.3 0.5 1.5e-13 51.1 0.5 1.0 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE YafQ_toxin PF15738.5 AIM23948.1 - 0.071 13.4 0.0 0.093 13.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial toxin of type II toxin-antitoxin system, YafQ Response_reg PF00072.24 AIM23949.1 - 1.7e-25 89.4 0.0 3.2e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain LytTR PF04397.15 AIM23949.1 - 6.7e-23 80.8 0.0 1.3e-22 79.8 0.0 1.5 1 0 0 1 1 1 1 LytTr DNA-binding domain 5TM-5TMR_LYT PF07694.12 AIM23950.1 - 1.9e-55 187.0 14.8 2.8e-55 186.4 14.8 1.3 1 0 0 1 1 1 1 5TMR of 5TMR-LYT His_kinase PF06580.13 AIM23950.1 - 7.6e-25 87.1 0.2 1.4e-24 86.2 0.2 1.4 1 0 0 1 1 1 1 Histidine kinase ECF-ribofla_trS PF07155.12 AIM23950.1 - 4e-05 23.7 8.5 8.7e-05 22.6 8.5 1.5 1 0 0 1 1 1 1 ECF-type riboflavin transporter, S component GAF_3 PF13492.6 AIM23950.1 - 8.6e-05 22.9 0.0 0.00026 21.4 0.0 1.7 2 0 0 2 2 2 1 GAF domain GAF_2 PF13185.6 AIM23950.1 - 0.00013 22.2 0.1 0.00079 19.7 0.0 2.2 2 1 0 2 2 2 1 GAF domain SpoVT_C PF15714.5 AIM23950.1 - 0.0031 17.6 0.0 0.0064 16.5 0.0 1.5 1 0 0 1 1 1 1 Stage V sporulation protein T C-terminal, transcription factor Toxin_23 PF08093.11 AIM23950.1 - 0.034 14.3 0.7 0.083 13.1 0.7 1.6 1 0 0 1 1 1 0 Magi 5 toxic peptide family HATPase_c PF02518.26 AIM23950.1 - 0.11 13.0 0.0 3.3 8.3 0.0 2.5 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ECF_trnsprt PF12822.7 AIM23950.1 - 0.88 9.6 12.9 3 7.9 12.9 1.8 1 1 0 1 1 1 0 ECF transporter, substrate-specific component Pro_isomerase PF00160.21 AIM23951.1 - 3e-48 164.1 0.5 3.5e-48 163.8 0.5 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PTS_IIA PF02255.16 AIM23952.1 - 2.3e-29 101.3 2.6 2.6e-29 101.1 2.6 1.0 1 0 0 1 1 1 1 PTS system, Lactose/Cellobiose specific IIA subunit Glyco_hydro_4 PF02056.16 AIM23953.1 - 1.4e-54 184.5 0.0 1.9e-54 184.0 0.0 1.2 1 0 0 1 1 1 1 Family 4 glycosyl hydrolase Glyco_hydro_4C PF11975.8 AIM23953.1 - 2.2e-51 174.9 0.0 3.4e-51 174.3 0.0 1.3 1 0 0 1 1 1 1 Family 4 glycosyl hydrolase C-terminal domain Ldh_1_N PF00056.23 AIM23953.1 - 0.027 14.6 0.1 0.13 12.3 0.0 2.0 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Peripla_BP_3 PF13377.6 AIM23954.1 - 1e-34 120.3 2.0 2.6e-34 118.9 0.2 2.2 3 0 0 3 3 3 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 AIM23954.1 - 5.4e-24 85.1 0.0 7.2e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 AIM23954.1 - 1e-19 70.0 0.7 1.8e-19 69.2 0.7 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 AIM23954.1 - 4.7e-16 59.1 0.0 7e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain HTH_3 PF01381.22 AIM23954.1 - 5.5e-06 26.3 0.0 1.3e-05 25.1 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix HTH_31 PF13560.6 AIM23954.1 - 3.6e-05 24.0 0.4 9.9e-05 22.6 0.4 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 AIM23954.1 - 0.017 15.1 0.5 0.064 13.2 0.1 2.3 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_17 PF12728.7 AIM23954.1 - 0.034 14.3 0.0 0.098 12.9 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 AIM23954.1 - 0.071 12.9 0.0 0.27 11.1 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain HTH_19 PF12844.7 AIM23954.1 - 0.13 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain MFS_1 PF07690.16 AIM23955.1 - 1.5e-21 76.7 56.0 2.4e-21 76.1 45.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Amidohydro_3 PF07969.11 AIM23956.1 - 1e-57 196.7 0.5 5.5e-56 191.0 0.5 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 AIM23956.1 - 6.9e-17 61.8 0.0 8.3e-17 61.5 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family RP-C PF03428.13 AIM23956.1 - 0.14 11.8 0.1 0.27 10.9 0.1 1.5 1 0 0 1 1 1 0 Replication protein C N-terminal domain Pyr_redox_2 PF07992.14 AIM23957.1 - 1.4e-50 172.2 0.2 2.7e-50 171.3 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 AIM23957.1 - 1.7e-21 76.3 2.5 3.1e-15 56.3 2.8 2.6 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Pyr_redox PF00070.27 AIM23957.1 - 2.7e-16 59.9 6.3 4.9e-16 59.0 0.4 3.7 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 AIM23957.1 - 1e-14 54.3 0.0 2.5e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 AIM23957.1 - 1.3e-11 44.1 0.0 2.6e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rubredoxin_C PF18267.1 AIM23957.1 - 6e-10 38.9 1.0 1.2e-09 37.9 0.3 2.0 2 0 0 2 2 2 1 Rubredoxin NAD+ reductase C-terminal domain Pyr_redox_3 PF13738.6 AIM23957.1 - 1.4e-08 34.3 0.0 2.2e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AIM23957.1 - 0.008 15.3 0.3 0.19 10.8 0.3 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.6 AIM23957.1 - 0.021 14.8 3.6 8 6.4 0.0 3.8 3 1 1 4 4 4 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 AIM23957.1 - 0.026 13.8 0.5 0.059 12.7 0.1 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 AIM23957.1 - 0.027 13.2 0.7 2 7.0 0.0 2.9 3 0 0 3 3 3 0 HI0933-like protein DAO PF01266.24 AIM23957.1 - 0.039 13.5 4.5 3.8 7.0 0.1 3.6 3 1 1 4 4 4 0 FAD dependent oxidoreductase K_oxygenase PF13434.6 AIM23957.1 - 0.069 12.3 0.0 0.24 10.5 0.0 1.7 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 AIM23957.1 - 0.12 11.6 1.7 0.21 10.8 1.7 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.24 AIM23957.1 - 0.36 9.8 4.2 12 4.8 0.0 2.6 2 0 0 2 2 2 0 FAD binding domain 3HCDH_N PF02737.18 AIM23957.1 - 1.1 9.1 5.4 11 5.9 0.3 3.6 3 1 1 4 4 4 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rieske_2 PF13806.6 AIM23958.1 - 5.6e-39 132.3 0.0 6.2e-39 132.1 0.0 1.0 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Rieske PF00355.26 AIM23958.1 - 0.022 14.7 0.0 0.025 14.5 0.0 1.1 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain TP_methylase PF00590.20 AIM23959.1 - 4e-48 164.2 0.6 8.2e-48 163.2 0.5 1.6 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 AIM23959.1 - 1.4e-25 89.7 0.2 2.1e-24 86.0 0.0 2.2 2 0 0 2 2 2 1 Putative NAD(P)-binding CysG_dimeriser PF10414.9 AIM23959.1 - 1.3e-18 66.4 7.5 3.7e-18 65.0 7.5 1.9 1 0 0 1 1 1 1 Sirohaem synthase dimerisation region Sirohm_synth_M PF14824.6 AIM23959.1 - 1.3e-08 34.1 0.1 3.2e-08 32.9 0.1 1.7 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Shikimate_DH PF01488.20 AIM23959.1 - 0.022 14.8 0.1 3.4 7.7 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Radical_SAM PF04055.21 AIM23959.1 - 0.024 15.0 0.0 1.7 9.0 0.0 2.4 2 0 0 2 2 2 0 Radical SAM superfamily tRNA-synt_1b PF00579.25 AIM23960.1 - 1.1e-86 290.8 0.0 1.4e-86 290.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) HAD_2 PF13419.6 AIM23961.1 - 1.2e-37 129.8 0.0 1.4e-37 129.5 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AIM23961.1 - 6.8e-23 82.1 0.0 9.7e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AIM23961.1 - 2.4e-18 67.2 0.1 3.2e-18 66.8 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AIM23961.1 - 2.4e-09 37.1 0.0 4.9e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_3 PF08282.12 AIM23961.1 - 1.5e-05 24.9 0.0 0.99 9.1 0.0 3.1 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AIM23961.1 - 5.3e-05 23.3 0.0 0.0004 20.5 0.0 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Ribul_P_3_epim PF00834.19 AIM23962.1 - 3.3e-92 307.3 0.1 3.8e-92 307.1 0.1 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 AIM23962.1 - 7.3e-06 25.9 0.1 0.00032 20.5 0.0 2.3 2 1 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.21 AIM23962.1 - 0.016 14.7 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein PGM_PMM_II PF02879.16 AIM23962.1 - 0.029 15.0 0.0 0.12 13.0 0.0 2.0 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II MethyltransfD12 PF02086.15 AIM23963.1 - 4.4e-77 259.3 0.1 4.9e-77 259.1 0.1 1.0 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase SPOR PF05036.13 AIM23964.1 - 1.5e-11 44.5 0.6 3.4e-11 43.4 0.6 1.6 1 0 0 1 1 1 1 Sporulation related domain DHQ_synthase PF01761.20 AIM23965.1 - 1.1e-109 365.7 0.0 1.3e-109 365.4 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 AIM23965.1 - 2.6e-13 50.3 0.1 9.5e-13 48.4 0.1 1.8 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 AIM23965.1 - 3.6e-06 26.1 2.4 1.7e-05 23.9 2.4 1.9 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase SKI PF01202.22 AIM23966.1 - 7.1e-57 191.9 0.6 8e-57 191.8 0.6 1.0 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 AIM23966.1 - 4.3e-09 36.7 0.1 2.9e-06 27.5 0.0 2.1 1 1 1 2 2 2 2 AAA domain AAA_18 PF13238.6 AIM23966.1 - 1.1e-07 32.4 0.0 1.7e-07 31.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 AIM23966.1 - 3e-06 27.1 0.6 4.7e-05 23.2 0.0 2.6 2 1 1 3 3 3 1 Cytidylate kinase dNK PF01712.19 AIM23966.1 - 9.6e-06 25.6 0.1 0.015 15.1 0.0 2.2 2 0 0 2 2 2 2 Deoxynucleoside kinase Cytidylate_kin2 PF13189.6 AIM23966.1 - 1.2e-05 25.5 0.2 0.0022 18.2 0.0 2.4 1 1 1 2 2 2 1 Cytidylate kinase-like family AAA PF00004.29 AIM23966.1 - 0.00039 20.9 0.0 0.0012 19.3 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AIM23966.1 - 0.001 19.5 0.1 0.0026 18.2 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AIM23966.1 - 0.0015 18.8 0.0 0.0021 18.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 AIM23966.1 - 0.0022 18.0 0.0 0.0045 17.0 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE APS_kinase PF01583.20 AIM23966.1 - 0.0028 17.6 0.1 0.006 16.5 0.1 1.6 1 1 0 1 1 1 1 Adenylylsulphate kinase ABC_tran PF00005.27 AIM23966.1 - 0.0041 17.6 0.1 0.0098 16.4 0.1 1.9 1 1 0 1 1 1 1 ABC transporter AAA_25 PF13481.6 AIM23966.1 - 0.0045 16.6 0.3 0.015 14.9 0.3 1.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 AIM23966.1 - 0.0056 16.7 0.0 0.015 15.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 AIM23966.1 - 0.0069 15.9 0.0 0.015 14.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region Ploopntkinase3 PF18751.1 AIM23966.1 - 0.011 15.7 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_17 PF13207.6 AIM23966.1 - 0.012 16.1 3.3 0.051 14.0 0.9 2.8 1 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 AIM23966.1 - 0.012 15.3 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 AIM23966.1 - 0.016 15.6 0.0 0.035 14.5 0.0 1.7 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.6 AIM23966.1 - 0.021 15.1 0.0 0.13 12.5 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_PrkA PF08298.11 AIM23966.1 - 0.024 13.5 0.0 0.047 12.6 0.0 1.4 1 0 0 1 1 1 0 PrkA AAA domain His_biosynth PF00977.21 AIM23966.1 - 0.025 14.0 0.1 0.032 13.7 0.1 1.2 1 0 0 1 1 1 0 Histidine biosynthesis protein AAA_29 PF13555.6 AIM23966.1 - 0.041 13.6 0.0 0.079 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AIM23966.1 - 0.052 13.5 0.0 0.11 12.3 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase AAA_14 PF13173.6 AIM23966.1 - 0.075 13.1 0.1 0.28 11.2 0.0 2.0 1 1 1 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 AIM23966.1 - 0.078 13.1 0.2 0.55 10.3 0.2 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase Mg_chelatase PF01078.21 AIM23966.1 - 0.079 12.3 0.0 0.13 11.7 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 AIM23966.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.14 AIM23966.1 - 0.11 12.6 1.6 0.33 11.0 0.7 2.2 1 1 1 2 2 2 0 AAA domain (Cdc48 subfamily) Secretin PF00263.21 AIM23967.1 - 1e-45 155.5 0.9 1e-45 155.5 0.9 1.5 2 0 0 2 2 2 1 Bacterial type II and III secretion system protein Secretin_N PF03958.17 AIM23967.1 - 6.5e-11 42.5 1.1 7.8e-10 39.0 0.6 2.5 2 0 0 2 2 2 1 Bacterial type II/III secretion system short domain STN PF07660.14 AIM23967.1 - 0.0028 17.4 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 Secretin and TonB N terminus short domain Cons_hypoth95 PF03602.15 AIM23967.1 - 0.13 11.9 0.0 0.35 10.5 0.0 1.7 1 0 0 1 1 1 0 Conserved hypothetical protein 95 HofP PF10748.9 AIM23968.1 - 1e-09 38.0 2.8 1.2e-09 37.8 2.8 1.1 1 0 0 1 1 1 1 DNA utilization proteins HofP PAP_PilO PF06864.12 AIM23969.1 - 0.056 12.3 0.8 0.068 12.0 0.8 1.1 1 0 0 1 1 1 0 Pilin accessory protein (PilO) PilN PF05137.13 AIM23970.1 - 2.2e-10 40.5 0.0 4.8e-10 39.4 0.0 1.5 2 0 0 2 2 2 1 Fimbrial assembly protein (PilN) SfLAP PF11139.8 AIM23970.1 - 0.038 13.4 0.1 0.051 13.0 0.1 1.2 1 0 0 1 1 1 0 Sap, sulfolipid-1-addressing protein OATP PF03137.20 AIM23970.1 - 0.29 9.4 0.0 0.31 9.3 0.0 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family PilM_2 PF11104.8 AIM23971.1 - 5e-12 45.5 0.0 2.5e-11 43.2 0.0 1.8 2 0 0 2 2 2 1 Type IV pilus assembly protein PilM; Transgly PF00912.22 AIM23972.1 - 7.4e-66 221.0 0.0 1.7e-65 219.8 0.0 1.6 1 0 0 1 1 1 1 Transglycosylase PCB_OB PF17092.5 AIM23972.1 - 2.9e-31 108.5 3.9 4.5e-31 107.9 2.8 2.0 2 0 0 2 2 2 1 Penicillin-binding protein OB-like domain Transpeptidase PF00905.22 AIM23972.1 - 8.6e-27 94.1 0.0 1.6e-24 86.7 0.0 2.6 2 1 0 2 2 2 2 Penicillin binding protein transpeptidase domain DUF3502 PF12010.8 AIM23972.1 - 0.021 15.4 0.0 0.047 14.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3502) NUDIX PF00293.28 AIM23973.1 - 2.3e-13 50.3 0.0 3.1e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain IgaA PF07095.11 AIM23974.1 - 0 1156.2 0.0 0 1156.0 0.0 1.0 1 0 0 1 1 1 1 Intracellular growth attenuator protein IgaA Metal_resist PF13801.6 AIM23974.1 - 0.0034 17.6 0.0 0.0085 16.3 0.0 1.7 1 0 0 1 1 1 1 Heavy-metal resistance EI24 PF07264.11 AIM23974.1 - 0.4 10.9 0.0 0.4 10.9 0.0 2.9 4 0 0 4 4 4 0 Etoposide-induced protein 2.4 (EI24) PSI_PsaJ PF01701.18 AIM23974.1 - 1.7 9.2 6.0 4.8 7.8 6.0 1.8 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ Hydrolase PF00702.26 AIM23975.1 - 5.4e-12 46.4 0.0 1.3e-07 32.1 0.0 2.1 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 AIM23975.1 - 5.2e-10 39.7 0.0 7.8e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 AIM23975.1 - 4.5e-06 27.2 0.5 5.6e-06 26.9 0.5 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AIM23975.1 - 0.0028 17.7 0.1 0.022 14.9 0.1 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase S4 PF01479.25 AIM23976.1 - 1.8e-12 46.8 0.0 2.9e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 AIM23976.1 - 0.099 12.5 0.0 0.24 11.3 0.0 1.7 1 1 0 1 1 1 0 S4 domain HSP33 PF01430.19 AIM23977.1 - 3.6e-87 292.2 0.1 4.1e-87 292.0 0.1 1.0 1 0 0 1 1 1 1 Hsp33 protein PEPCK_ATP PF01293.20 AIM23978.1 - 1.3e-209 696.6 0.0 1.5e-209 696.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 AIM23978.1 - 0.0028 17.8 0.3 0.43 10.7 0.1 2.9 3 0 0 3 3 3 2 AAA domain Arc PF03869.14 AIM23979.1 - 0.0054 16.5 0.2 0.0078 16.0 0.2 1.1 1 0 0 1 1 1 1 Arc-like DNA binding domain TraY PF05509.11 AIM23979.1 - 0.0059 16.6 0.3 0.0091 16.0 0.3 1.2 1 0 0 1 1 1 1 TraY domain PIN PF01850.21 AIM23980.1 - 7.3e-17 62.0 0.0 9.2e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 PIN domain PIN_3 PF13470.6 AIM23980.1 - 0.03 15.1 0.0 0.043 14.6 0.0 1.3 1 0 0 1 1 1 0 PIN domain DUF5615 PF18480.1 AIM23980.1 - 0.068 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) HATPase_c PF02518.26 AIM23981.1 - 3.5e-18 66.1 0.0 6.8e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AIM23981.1 - 8.6e-10 38.5 0.1 2e-09 37.4 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AIM23981.1 - 8.8e-09 35.6 0.1 2.5e-07 30.9 0.0 2.8 3 0 0 3 3 3 1 HAMP domain HATPase_c_3 PF13589.6 AIM23981.1 - 0.0072 16.2 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AIM23981.1 - 0.015 15.2 0.0 0.034 14.1 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Response_reg PF00072.24 AIM23982.1 - 9.6e-30 103.0 0.0 1.4e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AIM23982.1 - 9.1e-23 80.1 0.0 2.2e-22 78.9 0.0 1.7 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal FleQ PF06490.11 AIM23982.1 - 0.006 17.0 0.0 0.012 16.0 0.0 1.5 2 0 0 2 2 2 1 Flagellar regulatory protein FleQ MerR_2 PF13591.6 AIM23983.1 - 8.4e-21 73.6 0.1 9.5e-21 73.5 0.1 1.0 1 0 0 1 1 1 1 MerR HTH family regulatory protein Death PF00531.22 AIM23983.1 - 0.0081 16.3 0.6 0.011 15.8 0.6 1.2 1 0 0 1 1 1 1 Death domain HALZ PF02183.18 AIM23983.1 - 0.049 13.9 0.5 0.049 13.9 0.5 1.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF2399 PF09664.10 AIM23983.1 - 0.061 13.2 0.0 0.073 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2399) NYD-SP28_assoc PF14775.6 AIM23983.1 - 0.067 13.3 0.9 0.11 12.6 0.9 1.3 1 0 0 1 1 1 0 Sperm tail C-terminal domain DnaJ_C PF01556.18 AIM23984.1 - 4.8e-35 120.8 0.0 6.4e-35 120.4 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 AIM23984.1 - 7.3e-23 80.5 2.9 1.4e-22 79.5 2.9 1.5 1 0 0 1 1 1 1 DnaJ domain GreA_GreB_N PF03449.15 AIM23985.1 - 5.2e-27 93.8 1.2 7.3e-27 93.3 1.2 1.2 1 0 0 1 1 1 1 Transcription elongation factor, N-terminal GreA_GreB PF01272.19 AIM23985.1 - 1.6e-22 79.2 0.0 2.5e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 Transcription elongation factor, GreA/GreB, C-term Crl PF07417.12 AIM23985.1 - 0.081 13.0 0.1 0.18 11.9 0.0 1.5 1 1 0 1 1 1 0 Sigma factor-binding transcriptional regulator Crl Tex_N PF09371.10 AIM23986.1 - 1.2e-72 243.4 0.9 2.1e-72 242.6 0.9 1.4 1 0 0 1 1 1 1 Tex-like protein N-terminal domain Tex_YqgF PF16921.5 AIM23986.1 - 7.8e-50 168.6 0.4 1.4e-49 167.7 0.4 1.5 1 0 0 1 1 1 1 Tex protein YqgF-like domain HHH_3 PF12836.7 AIM23986.1 - 1.2e-28 99.1 0.0 3e-28 97.8 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif S1 PF00575.23 AIM23986.1 - 1.6e-23 82.8 0.7 3e-23 82.0 0.7 1.5 1 0 0 1 1 1 1 S1 RNA binding domain HHH_9 PF17674.1 AIM23986.1 - 2.4e-23 82.8 0.0 9.4e-23 80.9 0.0 2.1 1 0 0 1 1 1 1 HHH domain HHH_7 PF14635.6 AIM23986.1 - 2e-10 41.0 0.0 5.1e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 AIM23986.1 - 3.8e-07 30.0 0.0 9.8e-07 28.7 0.0 1.7 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_6 PF14579.6 AIM23986.1 - 0.064 13.5 0.0 0.28 11.4 0.0 2.1 1 0 0 1 1 1 0 Helix-hairpin-helix motif FeoA PF04023.14 AIM23987.1 - 5e-10 39.5 0.0 5.7e-10 39.3 0.0 1.0 1 0 0 1 1 1 1 FeoA domain FeoB_N PF02421.18 AIM23988.1 - 5.2e-63 211.2 0.6 8.1e-63 210.6 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B Gate PF07670.14 AIM23988.1 - 9.6e-49 164.3 15.1 6.7e-36 123.0 0.4 3.3 3 0 0 3 3 3 2 Nucleoside recognition FeoB_C PF07664.12 AIM23988.1 - 3.5e-22 77.8 1.3 1.8e-21 75.6 1.3 2.4 1 0 0 1 1 1 1 Ferrous iron transport protein B C terminus MMR_HSR1 PF01926.23 AIM23988.1 - 1e-19 70.7 0.0 3.4e-19 69.0 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_Cyto PF17910.1 AIM23988.1 - 4.7e-10 39.9 0.0 8.1e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 FeoB cytosolic helical domain SRPRB PF09439.10 AIM23988.1 - 8.7e-05 22.0 0.0 0.00014 21.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 AIM23988.1 - 0.0033 17.3 0.3 0.76 9.7 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 AIM23988.1 - 0.0068 16.5 0.1 3.5 7.7 0.0 2.4 2 0 0 2 2 2 2 Dynamin family ATP_bind_1 PF03029.17 AIM23988.1 - 0.0089 15.8 0.2 0.31 10.8 0.1 2.4 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 AIM23988.1 - 0.0097 15.5 0.1 0.86 9.1 0.1 2.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 AIM23988.1 - 0.09 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 AIG1 family DUF4229 PF14012.6 AIM23988.1 - 1.4 9.0 9.9 12 6.0 1.0 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) FeoC PF09012.10 AIM23989.1 - 1.8e-13 50.3 0.1 2e-13 50.2 0.1 1.0 1 0 0 1 1 1 1 FeoC like transcriptional regulator TrmB PF01978.19 AIM23989.1 - 0.0011 18.7 0.0 0.0011 18.7 0.0 1.1 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Fe_dep_repress PF01325.19 AIM23989.1 - 0.17 12.1 0.0 0.19 12.0 0.0 1.2 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain DUF1471 PF07338.13 AIM23990.1 - 1e-18 67.0 0.2 1.7e-18 66.3 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1471) Abhydrolase_1 PF00561.20 AIM23991.1 - 2.4e-25 89.7 0.1 2.9e-25 89.4 0.1 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AIM23991.1 - 7.2e-17 62.7 7.7 8.6e-17 62.5 7.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AIM23991.1 - 3.2e-10 39.7 0.1 1.3e-09 37.7 0.1 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 AIM23991.1 - 0.00023 21.0 0.0 3.9 7.2 0.0 3.1 3 0 0 3 3 3 3 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.7 AIM23991.1 - 0.00097 18.9 0.0 0.04 13.7 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.20 AIM23991.1 - 0.019 15.1 0.0 0.034 14.3 0.0 1.6 1 1 0 1 1 1 0 Thioesterase domain Pribosyltran PF00156.27 AIM23992.1 - 1.6e-08 34.2 0.1 3.9e-08 33.0 0.1 1.7 1 1 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 AIM23992.1 - 0.0064 16.0 0.9 0.058 12.9 0.2 2.1 1 1 1 2 2 2 2 Phosphoribosyl transferase UPRTase PF14681.6 AIM23992.1 - 0.0065 15.9 0.0 0.0092 15.4 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase NifU PF01106.17 AIM23993.1 - 6.1e-21 74.4 0.1 9.9e-21 73.7 0.1 1.4 1 0 0 1 1 1 1 NifU-like domain Fe-S_biosyn PF01521.20 AIM23993.1 - 1.2e-13 51.2 0.0 2.4e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Glyco_hydro_77 PF02446.17 AIM23994.1 - 3.8e-138 461.3 0.0 4.8e-138 460.9 0.0 1.0 1 0 0 1 1 1 1 4-alpha-glucanotransferase Phosphorylase PF00343.20 AIM23995.1 - 0 1019.7 0.0 0 1019.5 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase TPR_MalT PF17874.1 AIM23996.1 - 1.8e-110 369.5 30.2 1.8e-110 369.5 30.2 2.5 1 1 1 2 2 2 1 MalT-like TPR region GerE PF00196.19 AIM23996.1 - 1.1e-19 69.7 0.0 2.2e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family AAA_16 PF13191.6 AIM23996.1 - 3.6e-05 24.2 0.4 3.6e-05 24.2 0.4 4.9 5 2 0 5 5 5 1 AAA ATPase domain Sigma70_r4_2 PF08281.12 AIM23996.1 - 0.003 17.2 1.2 0.018 14.7 0.0 2.9 3 0 0 3 3 3 1 Sigma-70, region 4 TPR_8 PF13181.6 AIM23996.1 - 0.018 15.2 8.3 9.5 6.7 0.1 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat HTH_23 PF13384.6 AIM23996.1 - 0.019 14.8 1.9 0.033 14.0 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain RPN7 PF10602.9 AIM23996.1 - 0.025 14.3 0.6 4.2 7.0 0.0 3.2 2 2 1 3 3 3 0 26S proteasome subunit RPN7 AAA_22 PF13401.6 AIM23996.1 - 0.029 14.7 1.7 0.24 11.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain TPR_12 PF13424.6 AIM23996.1 - 0.03 14.6 42.0 0.027 14.7 4.2 7.7 7 2 0 7 7 7 0 Tetratricopeptide repeat Sigma70_r4 PF04545.16 AIM23996.1 - 0.06 12.9 0.0 0.18 11.4 0.0 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 TPR_19 PF14559.6 AIM23996.1 - 0.074 13.6 0.0 0.074 13.6 0.0 6.7 7 1 0 7 7 6 0 Tetratricopeptide repeat HTH_38 PF13936.6 AIM23996.1 - 0.075 12.8 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Penicillinase_R PF03965.16 AIM23996.1 - 0.1 12.9 0.3 0.62 10.4 0.0 2.5 2 0 0 2 2 2 0 Penicillinase repressor TPR_1 PF00515.28 AIM23996.1 - 0.36 10.7 5.8 42 4.2 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 AIM23996.1 - 0.43 11.4 38.2 2 9.3 0.2 9.7 10 0 0 10 10 8 0 Tetratricopeptide repeat TPR_2 PF07719.17 AIM23996.1 - 1.2 9.4 26.8 0.49 10.6 0.1 8.0 10 0 0 10 10 8 0 Tetratricopeptide repeat Aldolase_II PF00596.21 AIM23997.1 - 1.1e-46 159.2 0.3 1.4e-46 158.8 0.3 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain AP_endonuc_2 PF01261.24 AIM23998.1 - 2.4e-31 108.8 0.1 3.8e-31 108.2 0.1 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Glyco_hydro_114 PF03537.13 AIM23998.1 - 0.038 13.3 0.1 0.074 12.4 0.1 1.4 1 0 0 1 1 1 0 Glycoside-hydrolase family GH114 OMPdecase PF00215.24 AIM23999.1 - 7.3e-25 87.9 0.4 8.4e-25 87.7 0.4 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family PTS_EIIA_2 PF00359.22 AIM24000.1 - 2.1e-30 105.5 0.0 2.4e-30 105.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 PTS_IIB PF02302.17 AIM24001.1 - 1.5e-13 51.2 0.3 1.8e-13 51.0 0.3 1.1 1 0 0 1 1 1 1 PTS system, Lactose/Cellobiose specific IIB subunit IMPa_N_2 PF18650.1 AIM24001.1 - 0.046 13.0 0.0 0.055 12.7 0.0 1.1 1 0 0 1 1 1 0 Immunomodulating metalloprotease N-terminal domain Saccharop_dh_N PF04455.12 AIM24001.1 - 0.083 13.3 0.1 0.11 12.9 0.1 1.2 1 0 0 1 1 1 0 LOR/SDH bifunctional enzyme conserved region EIIC-GAT PF03611.14 AIM24002.1 - 1.5e-121 406.2 43.9 2.3e-121 405.7 43.9 1.2 1 0 0 1 1 1 1 PTS system sugar-specific permease component Lactamase_B_2 PF12706.7 AIM24003.1 - 2.2e-06 27.4 0.1 3.3e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 AIM24003.1 - 0.00014 21.8 0.0 0.00018 21.4 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF1840 PF08895.11 AIM24003.1 - 0.073 13.4 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) Lactamase_B_3 PF13483.6 AIM24004.1 - 6.4e-05 22.9 0.0 0.0001 22.2 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 AIM24004.1 - 0.0059 16.1 0.0 0.0079 15.7 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain TM231 PF10149.9 AIM24004.1 - 0.009 15.4 0.0 0.011 15.1 0.0 1.0 1 0 0 1 1 1 1 Transmembrane protein 231 DeoRC PF00455.22 AIM24005.1 - 1.7e-35 122.3 0.0 2.2e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 DeoR C terminal sensor domain HTH_DeoR PF08220.12 AIM24005.1 - 1.1e-17 63.5 0.5 3.2e-17 62.0 0.1 2.0 2 0 0 2 2 2 1 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 AIM24005.1 - 4.6e-06 26.5 0.3 9.2e-06 25.5 0.1 1.5 2 0 0 2 2 1 1 HTH domain HTH_24 PF13412.6 AIM24005.1 - 0.0002 20.9 0.1 0.00037 20.0 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 AIM24005.1 - 0.0022 17.7 0.0 0.0062 16.3 0.0 1.8 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_AsnC-type PF13404.6 AIM24005.1 - 0.0048 16.7 0.1 0.01 15.6 0.1 1.6 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain AbiEi_4 PF13338.6 AIM24005.1 - 0.012 15.8 0.0 0.027 14.6 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin Coatomer_g_Cpla PF16381.5 AIM24005.1 - 0.02 15.0 0.2 0.04 14.1 0.2 1.5 1 0 0 1 1 1 0 Coatomer subunit gamma-1 C-terminal appendage platform HTH_28 PF13518.6 AIM24005.1 - 0.02 15.0 0.7 0.056 13.6 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_20 PF12840.7 AIM24005.1 - 0.022 14.8 0.0 0.045 13.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Fe_dep_repress PF01325.19 AIM24005.1 - 0.026 14.7 0.1 0.098 12.9 0.0 1.9 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain F-112 PF09645.10 AIM24005.1 - 0.041 14.0 0.0 0.068 13.3 0.0 1.4 1 0 0 1 1 1 0 F-112 protein FeoC PF09012.10 AIM24005.1 - 0.058 13.5 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 FeoC like transcriptional regulator HTH_5 PF01022.20 AIM24005.1 - 0.095 12.6 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 AIM24005.1 - 0.097 12.6 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 MarR family HTH_23 PF13384.6 AIM24005.1 - 0.1 12.4 0.3 0.45 10.4 0.1 2.0 2 0 0 2 2 2 0 Homeodomain-like domain Rhodanese PF00581.20 AIM24006.1 - 2.5e-14 53.7 0.0 3.9e-14 53.1 0.0 1.3 1 1 0 1 1 1 1 Rhodanese-like domain Rhomboid PF01694.22 AIM24007.1 - 5.7e-28 97.8 19.0 5.7e-28 97.8 19.0 1.5 2 0 0 2 2 2 1 Rhomboid family Rhomboid_N PF12122.8 AIM24007.1 - 6.4e-28 96.8 0.1 9.8e-28 96.2 0.1 1.3 1 0 0 1 1 1 1 Cytoplasmic N-terminal domain of rhomboid serine protease Peptidase_A24 PF01478.18 AIM24007.1 - 6.8 7.1 14.3 2 8.9 0.2 2.4 2 1 0 2 2 2 0 Type IV leader peptidase family DeoRC PF00455.22 AIM24008.1 - 2.3e-54 183.6 0.0 3.8e-54 182.9 0.0 1.3 1 0 0 1 1 1 1 DeoR C terminal sensor domain HTH_DeoR PF08220.12 AIM24008.1 - 3.1e-24 84.5 0.0 7.5e-24 83.3 0.0 1.7 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 AIM24008.1 - 5.8e-07 29.4 0.0 1.1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 HTH domain GntR PF00392.21 AIM24008.1 - 7.5e-06 25.5 0.0 4.8e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family CoA_trans PF01144.23 AIM24008.1 - 0.0012 18.3 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 Coenzyme A transferase Methyltransf_28 PF02636.17 AIM24008.1 - 0.0036 17.0 0.0 0.0071 16.0 0.0 1.5 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase HTH_Crp_2 PF13545.6 AIM24008.1 - 0.027 14.4 0.1 0.28 11.2 0.0 2.2 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain Put_DNA-bind_N PF06971.13 AIM24008.1 - 0.031 14.3 0.0 0.056 13.5 0.0 1.4 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus HTH_28 PF13518.6 AIM24008.1 - 0.061 13.5 0.0 0.26 11.5 0.0 2.1 3 0 0 3 3 3 0 Helix-turn-helix domain DDRGK PF09756.9 AIM24008.1 - 0.073 12.6 0.1 0.1 12.2 0.1 1.2 1 0 0 1 1 1 0 DDRGK domain MarR_2 PF12802.7 AIM24008.1 - 0.086 12.7 0.0 0.23 11.4 0.0 1.7 2 0 0 2 2 2 0 MarR family Sigma70_ECF PF07638.11 AIM24008.1 - 0.11 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 ECF sigma factor TFIIE_alpha PF02002.17 AIM24008.1 - 0.11 12.3 0.0 0.49 10.3 0.0 2.0 2 0 0 2 2 2 0 TFIIE alpha subunit DUF977 PF06163.11 AIM24008.1 - 0.13 12.2 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) DAO PF01266.24 AIM24009.1 - 3.1e-49 168.4 0.0 3.1e-49 168.4 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO_C PF16901.5 AIM24009.1 - 1.7e-11 44.1 0.1 4.8e-11 42.6 0.1 1.8 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 AIM24009.1 - 0.00013 21.2 3.5 0.23 10.5 4.4 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 AIM24009.1 - 0.00087 19.5 1.5 0.011 15.9 0.9 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AIM24009.1 - 0.0026 17.0 0.0 0.011 15.0 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AIM24009.1 - 0.015 14.7 3.2 0.16 11.3 3.2 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 AIM24009.1 - 0.019 14.8 0.1 0.036 13.9 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 AIM24009.1 - 0.091 11.8 1.4 0.14 11.2 1.4 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 AIM24009.1 - 0.16 11.0 2.3 0.25 10.4 2.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 AIM24009.1 - 0.25 10.0 3.0 0.38 9.4 1.4 1.8 2 0 0 2 2 2 0 HI0933-like protein Phosphorylase PF00343.20 AIM24010.1 - 0 1075.9 0.0 0 1075.6 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate phosphorylase DUF2267 PF10025.9 AIM24010.1 - 0.074 13.3 0.6 44 4.4 0.0 3.5 3 1 1 4 4 4 0 Uncharacterized conserved protein (DUF2267) Glyco_transf_5 PF08323.11 AIM24011.1 - 6.4e-71 238.9 0.1 2.2e-70 237.2 0.0 1.9 2 0 0 2 2 2 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 AIM24011.1 - 1.5e-13 50.7 0.0 2.2e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 AIM24011.1 - 7.5e-12 46.0 3.7 2.6e-10 41.0 3.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 AIM24011.1 - 1.2e-10 41.6 2.7 2.7e-09 37.3 4.1 2.5 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 AIM24011.1 - 2.4e-07 31.2 0.1 4.6e-07 30.3 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF2267 PF10025.9 AIM24011.1 - 0.13 12.5 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) NTP_transferase PF00483.23 AIM24012.1 - 8.4e-69 231.9 0.0 1e-68 231.6 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AIM24012.1 - 1.8e-09 38.2 0.0 2.7e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 AIM24012.1 - 0.002 17.2 0.1 0.0086 15.1 0.1 1.8 2 0 0 2 2 2 1 L-fucokinase GlgX_C PF18390.1 AIM24013.1 - 1.2e-36 124.4 3.5 2.5e-36 123.3 3.5 1.6 1 0 0 1 1 1 1 Glycogen debranching enzyme C-terminal domain CBM_48 PF02922.18 AIM24013.1 - 7.7e-20 71.0 0.0 1.6e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 AIM24013.1 - 1e-09 38.4 0.1 0.002 17.8 0.0 3.1 1 1 0 2 2 2 2 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 AIM24013.1 - 0.028 12.7 0.0 0.041 12.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 70 DUF3459 PF11941.8 AIM24013.1 - 0.7 10.3 4.0 3.1 8.2 4.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3459) CBM_48 PF02922.18 AIM24014.1 - 3.7e-30 104.1 0.0 3.4e-25 88.2 0.0 2.7 2 0 0 2 2 2 2 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase_C PF02806.18 AIM24014.1 - 3.4e-20 72.3 0.0 6.8e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 AIM24014.1 - 5.6e-15 55.7 0.0 3e-10 40.2 0.0 2.2 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 AIM24014.1 - 0.029 12.6 0.0 0.051 11.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 70 LRR_10 PF18805.1 AIM24014.1 - 0.17 11.6 0.8 0.53 10.0 0.8 1.9 1 0 0 1 1 1 0 Leucine-rich repeat Semialdhyde_dhC PF02774.18 AIM24015.1 - 2.8e-58 197.0 0.0 3.5e-58 196.7 0.0 1.1 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 AIM24015.1 - 2.1e-24 86.3 0.0 3.6e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain MarC PF01914.17 AIM24016.1 - 6.2e-59 198.8 17.1 6.9e-59 198.6 17.1 1.0 1 0 0 1 1 1 1 MarC family integral membrane protein TerC PF03741.16 AIM24016.1 - 2.6e-06 27.2 1.3 2.6e-06 27.2 1.3 2.2 2 0 0 2 2 2 2 Integral membrane protein TerC family DUF1980 PF09323.10 AIM24016.1 - 0.066 13.1 2.0 0.095 12.6 2.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) AAA_33 PF13671.6 AIM24017.1 - 8.6e-07 29.2 0.0 1.3e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain SKI PF01202.22 AIM24017.1 - 2.2e-06 27.9 0.0 2.6e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 AIM24017.1 - 4.5e-05 24.0 0.0 6.1e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 AIM24017.1 - 0.0015 18.9 0.0 0.0034 17.8 0.0 1.6 1 1 1 2 2 2 1 AAA domain APS_kinase PF01583.20 AIM24017.1 - 0.027 14.4 0.0 0.029 14.3 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase Cytidylate_kin PF02224.18 AIM24017.1 - 0.059 13.1 0.0 0.074 12.8 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase AAA_16 PF13191.6 AIM24017.1 - 0.065 13.6 0.1 0.079 13.3 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 AIM24017.1 - 0.19 12.2 0.0 0.23 11.9 0.0 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) GntP_permease PF02447.16 AIM24018.1 - 2.6e-181 603.1 41.6 2.9e-181 603.0 41.6 1.0 1 0 0 1 1 1 1 GntP family permease CitMHS PF03600.16 AIM24018.1 - 1.6e-27 96.5 37.8 2.2e-27 96.0 37.8 1.2 1 0 0 1 1 1 1 Citrate transporter DUF3007 PF11460.8 AIM24018.1 - 0.11 12.8 0.7 0.39 11.0 0.7 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) Peripla_BP_1 PF00532.21 AIM24019.1 - 1.7e-29 103.1 0.0 2.2e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_3 PF13377.6 AIM24019.1 - 5e-25 88.7 0.1 1e-24 87.8 0.1 1.5 1 0 0 1 1 1 1 Periplasmic binding protein-like domain LacI PF00356.21 AIM24019.1 - 5.5e-17 61.3 0.1 1.9e-16 59.6 0.1 2.0 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 AIM24019.1 - 6.7e-11 42.2 0.0 9.5e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein domain HTH_3 PF01381.22 AIM24019.1 - 0.00056 19.9 0.0 0.0015 18.5 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix HTH_10 PF04967.12 AIM24019.1 - 0.011 15.5 0.0 0.044 13.6 0.0 2.1 1 0 0 1 1 1 0 HTH DNA binding domain HTH_23 PF13384.6 AIM24019.1 - 0.048 13.5 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_31 PF13560.6 AIM24019.1 - 0.11 12.8 0.0 0.32 11.4 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain rRNA_methylase PF06962.12 AIM24019.1 - 0.12 12.4 0.0 2.8 7.9 0.0 2.5 2 1 1 3 3 3 0 Putative rRNA methylase HTH_24 PF13412.6 AIM24019.1 - 0.13 11.8 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Pirin PF02678.16 AIM24020.1 - 5.3e-38 129.3 0.9 7.6e-38 128.8 0.9 1.2 1 0 0 1 1 1 1 Pirin Pirin_C_2 PF17954.1 AIM24020.1 - 1.4e-27 95.7 0.6 4e-27 94.2 0.1 1.9 2 0 0 2 2 2 1 Quercetinase C-terminal cupin domain Cupin_2 PF07883.11 AIM24020.1 - 2.1e-08 33.7 0.1 1.7e-07 30.8 0.2 2.1 2 0 0 2 2 2 1 Cupin domain Pirin_C PF05726.13 AIM24020.1 - 0.00065 20.0 0.0 0.28 11.5 0.0 2.2 2 0 0 2 2 2 2 Pirin C-terminal cupin domain Cupin_3 PF05899.12 AIM24020.1 - 0.11 12.2 0.0 1.5 8.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Acetyltransf_1 PF00583.25 AIM24021.1 - 1e-18 67.7 0.0 1.2e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AIM24021.1 - 1.4e-12 47.7 0.0 1.7e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AIM24021.1 - 3.3e-12 47.3 0.0 3.9e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AIM24021.1 - 4.4e-12 46.3 0.0 7e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AIM24021.1 - 1.6e-08 34.9 0.0 1.9e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AIM24021.1 - 9.4e-06 25.5 0.0 1.7e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 AIM24021.1 - 2.3e-05 24.5 0.0 6.9e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 AIM24021.1 - 0.00025 20.8 0.0 0.00035 20.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AIM24021.1 - 0.0014 18.7 0.0 0.004 17.2 0.0 1.8 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Peptidase_S58 PF03576.14 AIM24022.1 - 3.9e-58 197.3 7.2 4.9e-58 197.0 7.2 1.0 1 0 0 1 1 1 1 Peptidase family S58 AP_endonuc_2 PF01261.24 AIM24023.1 - 3.4e-25 88.7 0.0 5.3e-25 88.1 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel AP_endonuc_2_N PF07582.12 AIM24023.1 - 0.0049 16.6 0.0 0.073 12.8 0.0 2.4 2 0 0 2 2 2 1 AP endonuclease family 2 C terminus AP_endonuc_2 PF01261.24 AIM24024.1 - 1.7e-35 122.4 0.0 2.1e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel RtcR PF06956.11 AIM24024.1 - 0.013 14.9 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Regulator of RNA terminal phosphate cyclase GFO_IDH_MocA PF01408.22 AIM24025.1 - 6.4e-25 88.3 0.1 9.5e-25 87.8 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 AIM24025.1 - 2.3e-08 34.1 0.0 3.6e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain 2-Hacid_dh_C PF02826.19 AIM24025.1 - 0.0021 17.5 0.0 0.0044 16.4 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 AIM24025.1 - 0.0034 17.9 0.1 0.013 16.0 0.2 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 AIM24025.1 - 0.013 15.7 0.1 0.03 14.5 0.0 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Gp_dh_N PF00044.24 AIM24025.1 - 0.026 14.9 0.2 0.059 13.7 0.2 1.6 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 AIM24025.1 - 0.03 14.6 0.5 0.059 13.6 0.5 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain CoA_binding PF02629.19 AIM24025.1 - 0.043 14.5 0.3 0.29 11.8 0.1 2.2 2 0 0 2 2 2 0 CoA binding domain TPP_enzyme_C PF02775.21 AIM24026.1 - 5.5e-40 136.6 1.1 1.9e-39 134.9 0.1 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 AIM24026.1 - 3.5e-34 117.5 0.0 6.3e-34 116.6 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.18 AIM24026.1 - 2.2e-07 30.7 0.1 3.6e-06 26.7 0.0 2.5 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain DUF2090 PF09863.9 AIM24028.1 - 3e-139 463.3 0.3 5.1e-139 462.6 0.1 1.4 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2090) PfkB PF00294.24 AIM24028.1 - 4.8e-45 154.2 0.0 9.2e-45 153.2 0.0 1.5 1 1 0 1 1 1 1 pfkB family carbohydrate kinase DUF4148 PF13663.6 AIM24028.1 - 0.2 11.8 0.1 0.2 11.8 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) SIS PF01380.22 AIM24029.1 - 6.6e-26 90.7 0.1 1.1e-25 90.0 0.1 1.3 1 0 0 1 1 1 1 SIS domain HTH_6 PF01418.17 AIM24029.1 - 9.7e-13 47.9 0.9 1.9e-12 47.0 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain, rpiR family SIS_2 PF13580.6 AIM24029.1 - 0.004 17.2 0.2 0.015 15.3 0.0 2.0 2 1 0 2 2 2 1 SIS domain DASH_Dad3 PF08656.10 AIM24029.1 - 0.017 15.2 0.2 2.4 8.3 0.0 2.4 2 0 0 2 2 2 0 DASH complex subunit Dad3 KduI PF04962.12 AIM24030.1 - 1.2e-110 368.9 0.1 1.4e-110 368.7 0.1 1.0 1 0 0 1 1 1 1 KduI/IolB family Aldedh PF00171.22 AIM24031.1 - 2.4e-135 451.6 0.0 2.8e-135 451.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Sugar_tr PF00083.24 AIM24032.1 - 5.1e-104 348.7 34.6 5.8e-104 348.5 34.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 AIM24032.1 - 3.7e-37 128.1 35.1 3.7e-37 128.1 35.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 AIM24032.1 - 0.0034 16.0 6.6 0.0034 16.0 6.6 3.0 2 1 1 3 3 3 3 MFS/sugar transport protein AP_endonuc_2 PF01261.24 AIM24033.1 - 2.3e-13 50.1 0.1 5.3e-13 48.9 0.0 1.5 1 1 0 2 2 2 1 Xylose isomerase-like TIM barrel Band_7 PF01145.25 AIM24033.1 - 0.0015 18.6 0.3 0.0031 17.5 0.3 1.5 1 0 0 1 1 1 1 SPFH domain / Band 7 family UPF0014 PF03649.13 AIM24034.1 - 1.7e-82 276.4 15.8 1.9e-82 276.3 15.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) Ac76 PF05814.11 AIM24034.1 - 0.045 13.7 1.0 0.045 13.7 1.0 2.5 3 0 0 3 3 3 0 Orf76 (Ac76) Ammonium_transp PF00909.21 AIM24034.1 - 0.09 11.5 8.5 0.012 14.4 3.6 1.8 2 0 0 2 2 2 0 Ammonium Transporter Family DUF4231 PF14015.6 AIM24034.1 - 1.7 9.2 4.5 2.5 8.6 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) ABC_tran PF00005.27 AIM24035.1 - 1.1e-31 110.2 0.0 1.6e-31 109.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AIM24035.1 - 5.4e-10 39.1 0.7 3e-08 33.4 0.7 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 AIM24035.1 - 3.6e-06 27.0 0.1 0.00013 22.0 0.0 2.1 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_29 PF13555.6 AIM24035.1 - 7.2e-06 25.6 0.2 1.8e-05 24.4 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 AIM24035.1 - 7.3e-06 26.4 0.6 0.07 13.6 0.0 2.4 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 AIM24035.1 - 7.8e-06 25.9 0.4 0.0016 18.3 0.0 2.1 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_14 PF13173.6 AIM24035.1 - 0.00018 21.5 0.2 0.0053 16.8 0.0 2.4 3 0 0 3 3 2 1 AAA domain NTPase_1 PF03266.15 AIM24035.1 - 0.00037 20.5 0.2 0.11 12.4 0.0 2.2 2 0 0 2 2 2 1 NTPase AAA_11 PF13086.6 AIM24035.1 - 0.00041 20.2 0.0 0.0005 19.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AIM24035.1 - 0.00057 20.3 0.0 0.0012 19.3 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 AIM24035.1 - 0.00075 19.5 0.7 0.075 13.0 0.0 2.6 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 AIM24035.1 - 0.00085 19.9 0.1 0.0056 17.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 AIM24035.1 - 0.002 18.4 2.3 0.02 15.1 2.3 2.2 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 AIM24035.1 - 0.0024 17.9 0.1 0.0039 17.1 0.1 1.7 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 AIM24035.1 - 0.0034 17.3 0.0 0.0071 16.3 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 AIM24035.1 - 0.0036 16.9 0.1 0.1 12.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 AIM24035.1 - 0.0044 16.5 0.6 0.16 11.3 0.2 2.2 2 0 0 2 2 2 1 Bacterial TniB protein RNA_helicase PF00910.22 AIM24035.1 - 0.0059 17.0 0.0 0.013 15.8 0.0 1.6 2 0 0 2 2 1 1 RNA helicase NACHT PF05729.12 AIM24035.1 - 0.0066 16.4 0.2 0.13 12.2 0.0 2.2 2 0 0 2 2 2 1 NACHT domain SbcCD_C PF13558.6 AIM24035.1 - 0.0067 16.6 0.1 0.55 10.5 0.1 2.5 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Adeno_IVa2 PF02456.15 AIM24035.1 - 0.0081 15.0 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Adenovirus IVa2 protein AAA_30 PF13604.6 AIM24035.1 - 0.0099 15.6 0.0 0.032 14.0 0.0 1.8 2 1 1 3 3 2 1 AAA domain AAA_23 PF13476.6 AIM24035.1 - 0.014 15.9 3.1 0.02 15.4 3.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 AIM24035.1 - 0.024 14.9 0.3 0.12 12.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 AIM24035.1 - 0.027 14.2 0.0 0.037 13.7 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain ABC_ATPase PF09818.9 AIM24035.1 - 0.029 13.2 0.2 7.7 5.2 0.0 2.7 2 1 0 2 2 2 0 Predicted ATPase of the ABC class T2SSE PF00437.20 AIM24035.1 - 0.035 13.2 0.1 0.067 12.2 0.0 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein Mg_chelatase PF01078.21 AIM24035.1 - 0.043 13.2 0.0 0.094 12.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_27 PF13514.6 AIM24035.1 - 0.049 13.2 0.0 0.094 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 AIM24035.1 - 0.056 13.1 0.0 0.058 13.0 0.0 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain KAP_NTPase PF07693.14 AIM24035.1 - 0.069 12.4 0.0 0.25 10.5 0.0 1.8 1 1 1 2 2 2 0 KAP family P-loop domain PRK PF00485.18 AIM24035.1 - 0.097 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family ATPase PF06745.13 AIM24035.1 - 0.12 11.8 0.1 5 6.4 0.0 2.2 2 0 0 2 2 2 0 KaiC RuvB_N PF05496.12 AIM24035.1 - 0.89 9.3 3.3 1.3 8.7 0.1 2.6 2 2 2 4 4 4 0 Holliday junction DNA helicase RuvB P-loop domain FaeA PF04703.12 AIM24036.1 - 6e-05 23.3 0.0 9.2e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 FaeA-like protein DUF4702 PF15774.5 AIM24036.1 - 0.039 12.9 0.0 0.039 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4702) FKBP_N PF01346.18 AIM24037.1 - 5.7e-14 52.9 0.0 5.7e-14 52.9 0.0 2.6 2 1 1 3 3 3 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase FKBP_C PF00254.28 AIM24037.1 - 4.2e-06 27.0 0.0 7.9e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Med9 PF07544.13 AIM24037.1 - 0.071 13.2 5.4 0.85 9.8 0.8 2.7 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 MetOD2 PF18548.1 AIM24037.1 - 0.092 12.9 0.6 0.3 11.2 0.0 2.2 3 0 0 3 3 3 0 Metanogen output domain 2 TACC_C PF05010.14 AIM24037.1 - 0.26 11.0 4.7 0.63 9.8 4.7 1.6 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF1515 PF07439.11 AIM24037.1 - 0.53 10.3 3.6 0.37 10.8 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) Csm1_N PF18504.1 AIM24037.1 - 0.72 10.2 9.7 3.6 8.0 0.3 2.9 3 0 0 3 3 3 0 Csm1 N-terminal domain FlgN PF05130.12 AIM24037.1 - 2.4 8.6 22.0 3.4 8.2 13.2 3.0 1 1 1 2 2 2 0 FlgN protein Lebercilin PF15619.6 AIM24037.1 - 3 7.4 15.4 0.048 13.3 1.3 2.7 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Spc7 PF08317.11 AIM24037.1 - 4 6.2 7.7 1.1 8.1 0.6 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein Spc24 PF08286.11 AIM24037.1 - 6.2 7.1 5.9 3.3 8.0 0.5 2.5 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 Fimbrial PF00419.20 AIM24039.1 - 2.2e-17 63.7 1.1 3.1e-17 63.2 1.1 1.1 1 0 0 1 1 1 1 Fimbrial protein Fimbrial PF00419.20 AIM24040.1 - 3.4e-11 43.6 0.0 4.4e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Fimbrial protein Leu_leader PF08054.11 AIM24040.1 - 0.16 11.6 0.4 0.28 10.8 0.4 1.4 1 0 0 1 1 1 0 Leucine operon leader peptide Usher PF00577.20 AIM24041.1 - 3.2e-174 580.8 21.4 3.9e-174 580.6 21.4 1.1 1 0 0 1 1 1 1 Outer membrane usher protein PapC_N PF13954.6 AIM24041.1 - 1.8e-38 131.8 0.0 3.7e-38 130.8 0.0 1.6 1 0 0 1 1 1 1 PapC N-terminal domain PapC_C PF13953.6 AIM24041.1 - 3.7e-15 55.5 0.1 1.1e-14 54.0 0.0 1.9 2 0 0 2 2 2 1 PapC C-terminal domain PapD_N PF00345.20 AIM24042.1 - 7.6e-37 126.0 2.7 1.8e-36 124.8 2.8 1.6 2 0 0 2 2 2 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain PapD_C PF02753.17 AIM24042.1 - 3.2e-14 53.0 0.6 1.8e-13 50.6 0.1 2.5 2 1 0 2 2 2 1 Pili assembly chaperone PapD, C-terminal domain Fimbrial PF00419.20 AIM24043.1 - 3.5e-11 43.6 0.0 4.7e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Fimbrial protein PapJ PF14855.6 AIM24043.1 - 0.11 12.2 0.1 0.2 11.3 0.1 1.3 1 0 0 1 1 1 0 Pilus-assembly fibrillin subunit, chaperone Fimbrial PF00419.20 AIM24044.1 - 5.9e-17 62.3 0.1 1.2e-16 61.4 0.1 1.5 1 0 0 1 1 1 1 Fimbrial protein HU-DNA_bdg PF14848.6 AIM24044.1 - 0.18 11.8 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 DNA-binding domain Fimbrial PF00419.20 AIM24045.1 - 1.1e-14 55.0 1.7 1.3e-14 54.7 1.7 1.1 1 0 0 1 1 1 1 Fimbrial protein GerE PF00196.19 AIM24046.1 - 6.6e-12 44.8 1.1 1e-11 44.2 1.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_38 PF13936.6 AIM24046.1 - 0.035 13.9 0.1 0.091 12.5 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 AIM24046.1 - 0.095 12.2 0.3 0.27 10.8 0.0 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 Fimbrial PF00419.20 AIM24047.1 - 5.6e-11 42.9 0.6 4.6e-09 36.7 0.3 2.2 2 0 0 2 2 2 2 Fimbrial protein DUF834 PF05754.14 AIM24047.1 - 0.14 12.2 0.1 0.32 11.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF834) Usher PF00577.20 AIM24048.1 - 3.3e-165 551.1 19.8 4e-165 550.8 19.8 1.1 1 0 0 1 1 1 1 Outer membrane usher protein PapC_N PF13954.6 AIM24048.1 - 8.9e-41 139.3 0.0 4.8e-40 136.9 0.0 2.0 2 0 0 2 2 2 1 PapC N-terminal domain PapC_C PF13953.6 AIM24048.1 - 3.7e-18 65.1 0.8 2e-17 62.8 0.1 2.6 2 0 0 2 2 2 1 PapC C-terminal domain Big_6 PF17936.1 AIM24048.1 - 0.019 15.2 0.1 0.084 13.2 0.1 2.1 1 0 0 1 1 1 0 Bacterial Ig domain PapD_N PF00345.20 AIM24049.1 - 3.5e-45 152.9 0.0 4.5e-45 152.6 0.0 1.1 1 0 0 1 1 1 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain PapD_C PF02753.17 AIM24049.1 - 1e-13 51.4 1.3 2.4e-13 50.2 0.1 2.3 3 0 0 3 3 3 1 Pili assembly chaperone PapD, C-terminal domain FimA PF16970.5 AIM24050.1 - 2.1e-10 40.9 6.1 8.9e-10 38.9 6.1 1.8 1 1 0 1 1 1 1 Type-1 fimbrial protein, A Trans_reg_C PF00486.28 AIM24051.1 - 2.3e-10 40.4 0.1 3.2e-10 40.0 0.1 1.2 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal EamA PF00892.20 AIM24052.1 - 2.7e-24 85.9 34.7 2.6e-12 47.1 8.0 2.0 2 0 0 2 2 2 2 EamA-like transporter family SrfB PF07520.11 AIM24054.1 - 0 1344.6 0.0 0 1344.4 0.0 1.0 1 0 0 1 1 1 1 Virulence factor SrfB Virul_Fac PF10139.9 AIM24055.1 - 5.3e-105 352.5 7.6 2e-48 165.4 0.5 4.8 1 1 2 3 3 3 3 Putative bacterial virulence factor HsbA PF12296.8 AIM24055.1 - 0.15 12.5 1.6 0.38 11.2 0.9 2.1 2 0 0 2 2 2 0 Hydrophobic surface binding protein A Glyoxalase PF00903.25 AIM24056.1 - 8.7e-15 55.1 0.0 1e-14 54.8 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 AIM24056.1 - 0.00067 19.9 0.0 0.001 19.3 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 AIM24056.1 - 0.0067 17.2 0.0 0.013 16.3 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 AIM24056.1 - 0.016 15.1 0.0 0.075 13.0 0.0 1.9 1 1 0 1 1 1 0 Glyoxalase-like domain Flavi_M PF01004.19 AIM24057.1 - 0.13 12.0 0.3 5.5 6.8 0.0 2.1 2 0 0 2 2 2 0 Flavivirus envelope glycoprotein M HI0933_like PF03486.14 AIM24058.1 - 4.1e-154 513.2 0.0 4.6e-154 513.0 0.0 1.0 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 AIM24058.1 - 4.1e-10 39.3 3.1 1.4e-07 31.0 0.4 2.8 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.24 AIM24058.1 - 6.3e-10 39.2 2.8 4.5e-05 23.2 0.1 3.0 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 AIM24058.1 - 1.4e-09 37.6 0.0 3.4e-09 36.4 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AIM24058.1 - 2.2e-08 33.6 0.2 2e-05 23.9 0.0 2.5 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 AIM24058.1 - 4.5e-08 32.9 0.1 7e-08 32.2 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 AIM24058.1 - 9.6e-08 31.6 0.2 0.014 14.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 AIM24058.1 - 1.4e-05 24.4 0.8 0.0016 17.5 0.5 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 AIM24058.1 - 1.4e-05 25.2 1.0 1.4e-05 25.2 1.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 AIM24058.1 - 0.00061 20.3 0.3 0.021 15.4 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 AIM24058.1 - 0.001 18.4 1.2 0.019 14.3 1.3 2.2 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 AIM24058.1 - 0.0014 18.0 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 AIM24058.1 - 0.0025 17.8 0.0 0.0066 16.4 0.0 1.8 1 1 0 1 1 1 1 FAD-NAD(P)-binding Thi4 PF01946.17 AIM24058.1 - 0.02 14.2 0.1 0.055 12.7 0.1 1.8 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.19 AIM24058.1 - 0.026 13.8 0.3 0.17 11.1 0.2 1.9 2 0 0 2 2 2 0 FAD binding domain PHO4 PF01384.20 AIM24059.1 - 7.7e-91 304.6 17.9 9.1e-91 304.4 17.9 1.0 1 0 0 1 1 1 1 Phosphate transporter family Rax2 PF12768.7 AIM24059.1 - 0.36 10.3 2.1 0.55 9.6 0.0 2.3 3 0 0 3 3 3 0 Cortical protein marker for cell polarity UspB PF10625.9 AIM24060.1 - 1.4e-54 182.6 1.2 1.6e-54 182.4 1.2 1.0 1 0 0 1 1 1 1 Universal stress protein B (UspB) PsbN PF02468.15 AIM24060.1 - 0.34 10.8 0.0 0.34 10.8 0.0 2.5 3 0 0 3 3 3 0 Photosystem II reaction centre N protein (psbN) adh_short_C2 PF13561.6 AIM24061.1 - 1.1e-42 146.2 2.0 1.3e-42 145.9 2.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AIM24061.1 - 5.5e-31 107.6 1.7 7.2e-31 107.2 1.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AIM24061.1 - 7.5e-12 45.5 0.7 9.6e-12 45.2 0.7 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AIM24061.1 - 0.00092 18.7 0.3 0.0083 15.6 0.2 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family YjeF_N PF03853.15 AIM24061.1 - 0.031 14.2 1.6 0.041 13.8 1.6 1.5 1 1 0 1 1 1 0 YjeF-related protein N-terminus THF_DHG_CYH_C PF02882.19 AIM24061.1 - 0.11 11.8 1.2 0.21 10.9 1.2 1.5 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain LysR_substrate PF03466.20 AIM24062.1 - 2.9e-39 134.6 5.8 2.9e-39 134.6 5.8 1.4 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AIM24062.1 - 3e-19 68.7 1.4 5.9e-19 67.8 1.4 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family Usp PF00582.26 AIM24063.1 - 1.4e-20 74.2 0.0 1.6e-20 74.0 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family ETF PF01012.21 AIM24063.1 - 0.0047 16.8 0.0 0.087 12.7 0.0 2.1 2 0 0 2 2 2 1 Electron transfer flavoprotein domain TPP_enzyme_M PF00205.22 AIM24063.1 - 0.019 14.7 0.0 0.54 10.0 0.0 2.7 2 1 1 3 3 3 0 Thiamine pyrophosphate enzyme, central domain ELFV_dehydrog PF00208.21 AIM24064.1 - 7.2e-86 287.9 1.2 8.9e-86 287.6 1.2 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 AIM24064.1 - 3.1e-50 169.4 0.0 6e-50 168.5 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.6 AIM24064.1 - 0.011 16.2 0.0 0.019 15.4 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding XdhC_C PF13478.6 AIM24064.1 - 0.041 14.4 0.1 2.9 8.4 0.0 2.7 3 0 0 3 3 3 0 XdhC Rossmann domain 2-Hacid_dh_C PF02826.19 AIM24064.1 - 0.1 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Peripla_BP_4 PF13407.6 AIM24065.1 - 2.2e-53 181.5 7.5 2.6e-53 181.2 7.5 1.0 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 AIM24065.1 - 0.013 14.9 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family ABC_tran PF00005.27 AIM24066.1 - 3.1e-54 183.2 0.0 7.8e-28 97.7 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 AIM24066.1 - 2.4e-05 24.3 0.0 0.004 17.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIM24066.1 - 0.00014 21.4 1.6 0.54 9.6 0.1 3.3 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 AIM24066.1 - 0.0008 19.4 0.6 0.026 14.4 0.1 3.0 4 0 0 4 4 4 1 RsgA GTPase AAA_29 PF13555.6 AIM24066.1 - 0.002 17.8 0.1 0.0093 15.7 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 AIM24066.1 - 0.0033 16.7 0.0 0.011 15.0 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_23 PF13476.6 AIM24066.1 - 0.0036 17.8 0.2 0.014 15.9 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 AIM24066.1 - 0.0069 16.1 0.1 0.0096 15.7 0.1 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 AIM24066.1 - 0.0096 15.5 0.2 0.44 10.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 AIM24066.1 - 0.022 14.4 0.5 0.14 11.8 0.2 2.2 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.6 AIM24066.1 - 0.028 14.1 0.8 0.23 11.1 0.4 2.5 2 1 0 2 2 2 0 AAA domain Rad17 PF03215.15 AIM24066.1 - 0.033 14.1 0.0 0.091 12.7 0.1 1.6 2 0 0 2 2 2 0 Rad17 P-loop domain AAA PF00004.29 AIM24066.1 - 0.045 14.2 0.8 2.3 8.7 0.0 3.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Peptidase_M23_N PF18421.1 AIM24066.1 - 0.056 13.4 0.0 0.33 10.9 0.0 2.2 2 0 0 2 2 2 0 Peptidase family M23 N-terminal domain AAA_18 PF13238.6 AIM24066.1 - 0.068 13.7 0.1 14 6.2 0.0 3.7 4 0 0 4 4 4 0 AAA domain TsaE PF02367.17 AIM24066.1 - 0.12 12.4 0.1 16 5.5 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DnaB_C PF03796.15 AIM24066.1 - 0.17 11.2 0.6 4.5 6.5 0.0 2.8 3 0 0 3 3 3 0 DnaB-like helicase C terminal domain ATPase PF06745.13 AIM24066.1 - 0.31 10.4 1.5 3.4 7.0 0.0 2.7 4 0 0 4 4 4 0 KaiC AAA_33 PF13671.6 AIM24066.1 - 0.58 10.3 1.8 3.3 7.9 0.2 2.6 2 1 0 2 2 2 0 AAA domain BPD_transp_2 PF02653.16 AIM24067.1 - 7e-44 150.0 39.5 1e-43 149.5 39.5 1.2 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component BPD_transp_2 PF02653.16 AIM24068.1 - 1.1e-36 126.3 48.1 1.1e-36 126.3 48.1 1.4 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component FGGY_C PF02782.16 AIM24069.1 - 2.1e-40 138.6 1.1 3.2e-40 138.0 1.1 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 AIM24069.1 - 4.8e-32 111.5 0.0 7.5e-32 110.8 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 AIM24069.1 - 0.0078 15.7 0.5 0.7 9.3 0.1 3.1 2 2 1 4 4 4 1 BadF/BadG/BcrA/BcrD ATPase family SIS PF01380.22 AIM24070.1 - 2.5e-22 79.1 0.4 4.1e-22 78.4 0.3 1.4 2 0 0 2 2 2 1 SIS domain SIS_2 PF13580.6 AIM24070.1 - 0.00088 19.3 0.5 0.075 13.0 0.0 2.7 1 1 1 3 3 3 1 SIS domain DUF2529 PF10740.9 AIM24070.1 - 0.0042 16.7 0.0 0.0058 16.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2529) AhpC-TSA_2 PF13911.6 AIM24070.1 - 0.019 15.1 0.0 1.1 9.4 0.0 2.4 2 0 0 2 2 2 0 AhpC/TSA antioxidant enzyme AlaDh_PNT_C PF01262.21 AIM24070.1 - 0.03 13.6 0.1 4.7 6.4 0.0 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain PPS_PS PF02006.16 AIM24070.1 - 0.15 11.6 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Phosphopantothenate/pantothenate synthetase DUF1147 PF06615.11 AIM24070.1 - 0.43 10.6 2.6 31 4.7 0.0 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF1147) SAM_MT PF04445.13 AIM24071.1 - 7.6e-108 359.3 0.0 8.6e-108 359.1 0.0 1.0 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase TilS_C PF11734.8 AIM24071.1 - 0.091 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 TilS substrate C-terminal domain Peptidase_M3 PF01432.20 AIM24072.1 - 8.3e-168 559.4 0.0 1e-167 559.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 PSII_Pbs27 PF13326.6 AIM24072.1 - 0.062 13.6 0.7 1.2 9.5 0.1 2.5 2 0 0 2 2 2 0 Photosystem II Pbs27 HIT PF01230.23 AIM24073.1 - 1.9e-10 41.4 0.0 3.1e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 AIM24073.1 - 0.0017 18.8 0.0 0.0022 18.5 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding FliW PF02623.15 AIM24073.1 - 0.14 12.1 0.0 0.29 11.1 0.0 1.5 2 0 0 2 2 2 0 FliW protein ASCH PF04266.14 AIM24074.1 - 7.2e-22 78.0 0.0 7.9e-22 77.9 0.0 1.0 1 0 0 1 1 1 1 ASCH domain RsmJ PF04378.13 AIM24075.1 - 3.8e-112 373.4 0.0 4.5e-112 373.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA large subunit methyltransferase D, RlmJ Cons_hypoth95 PF03602.15 AIM24075.1 - 0.00056 19.6 0.0 0.027 14.1 0.0 2.4 3 0 0 3 3 3 2 Conserved hypothetical protein 95 Pyr_redox_2 PF07992.14 AIM24076.1 - 1.3e-68 231.4 3.2 1.3e-68 231.4 3.2 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 AIM24076.1 - 1.1e-34 119.0 3.8 1.1e-34 119.0 1.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_3 PF13738.6 AIM24076.1 - 9.7e-18 64.5 4.0 5.3e-17 62.0 4.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AIM24076.1 - 3.7e-17 62.6 1.6 5.1e-17 62.2 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AIM24076.1 - 0.00028 19.7 3.1 0.4 9.3 0.0 3.2 2 1 1 3 3 3 2 HI0933-like protein GIDA PF01134.22 AIM24076.1 - 0.0004 19.6 1.8 0.0046 16.1 0.1 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A K_oxygenase PF13434.6 AIM24076.1 - 0.0014 17.8 0.0 0.0023 17.1 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.19 AIM24076.1 - 0.032 13.6 0.1 0.2 11.0 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 AIM24076.1 - 0.043 13.1 1.1 0.64 9.3 0.1 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 AIM24076.1 - 0.044 13.1 0.2 0.086 12.2 0.1 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AIM24076.1 - 0.83 8.7 7.7 4.5 6.2 0.1 2.9 3 1 0 3 3 3 0 FAD binding domain Oxidored_molyb PF00174.19 AIM24077.1 - 1e-09 38.3 0.0 1.2e-08 34.8 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase molybdopterin binding domain HATPase_c PF02518.26 AIM24078.1 - 2e-25 89.5 0.1 3.5e-25 88.7 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AIM24078.1 - 4.1e-18 65.6 0.0 1.9e-17 63.4 0.0 2.2 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 AIM24078.1 - 1.8e-07 31.1 1.0 7.5e-07 29.1 0.2 2.5 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 AIM24078.1 - 0.00014 21.7 0.2 0.0012 18.7 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FleQ PF06490.11 AIM24078.1 - 0.031 14.6 0.0 0.068 13.6 0.0 1.6 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ DUF3671 PF12420.8 AIM24078.1 - 0.098 12.7 1.4 0.33 11.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF1003 PF06210.11 AIM24078.1 - 1.9 8.6 5.2 1.8 8.7 1.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1003) BetR PF08667.10 AIM24079.1 - 4.6e-33 114.4 0.0 6.8e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 BetR domain Response_reg PF00072.24 AIM24079.1 - 9.8e-05 22.5 0.0 0.00015 21.9 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain HTH_26 PF13443.6 AIM24079.1 - 0.0033 17.8 0.0 0.012 16.1 0.0 1.9 2 0 0 2 2 2 1 Cro/C1-type HTH DNA-binding domain DUF1601 PF07671.11 AIM24079.1 - 0.27 11.1 0.7 0.66 9.9 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1601) Autotransporter PF03797.19 AIM24080.1 - 8e-59 199.3 25.2 2.2e-58 197.9 25.2 1.8 1 0 0 1 1 1 1 Autotransporter beta-domain Peptidase_S8 PF00082.22 AIM24080.1 - 7.7e-45 153.4 2.2 1.9e-44 152.1 2.2 1.7 1 0 0 1 1 1 1 Subtilase family PATR PF12951.7 AIM24080.1 - 6.7e-11 42.1 2.9 6.7e-11 42.1 2.9 2.7 2 0 0 2 2 2 1 Passenger-associated-transport-repeat Autotransporter PF03797.19 AIM24081.1 - 1.8e-58 198.2 26.5 5.6e-58 196.6 26.5 1.9 1 0 0 1 1 1 1 Autotransporter beta-domain Peptidase_S8 PF00082.22 AIM24081.1 - 9.7e-47 159.7 3.4 2.4e-46 158.4 3.4 1.7 1 0 0 1 1 1 1 Subtilase family PATR PF12951.7 AIM24081.1 - 6.5e-11 42.1 2.9 6.5e-11 42.1 2.9 2.9 2 0 0 2 2 2 1 Passenger-associated-transport-repeat TetR_N PF00440.23 AIM24082.1 - 2.3e-06 27.3 0.1 4.2e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_7 PF02796.15 AIM24082.1 - 0.00021 21.3 0.0 0.0004 20.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_36 PF13730.6 AIM24082.1 - 0.0064 16.4 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.10 AIM24082.1 - 0.049 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain INTS5_C PF14838.6 AIM24082.1 - 0.13 10.8 0.1 0.14 10.8 0.1 1.1 1 0 0 1 1 1 0 Integrator complex subunit 5 C-terminus UPF0261 PF06792.11 AIM24083.1 - 2.7e-131 438.3 0.0 3e-131 438.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) Gate PF07670.14 AIM24083.1 - 0.13 12.6 0.1 0.27 11.5 0.1 1.5 1 0 0 1 1 1 0 Nucleoside recognition LTXXQ PF07813.12 AIM24084.1 - 1e-19 71.2 7.7 1e-19 71.2 7.7 2.7 1 1 2 3 3 3 1 LTXXQ motif family protein Metal_resist PF13801.6 AIM24084.1 - 1.4e-10 41.4 14.0 6.3e-08 32.9 9.3 2.5 1 1 1 2 2 2 2 Heavy-metal resistance CBP4 PF07960.11 AIM24084.1 - 0.017 14.9 4.2 0.017 14.9 4.2 2.3 1 1 1 2 2 2 0 CBP4 YbgS PF13985.6 AIM24084.1 - 0.042 14.1 1.9 0.042 14.1 1.9 2.0 2 1 0 2 2 2 0 YbgS-like protein HMG_box PF00505.19 AIM24084.1 - 0.064 13.7 4.5 0.064 13.7 4.5 1.9 2 1 0 2 2 2 0 HMG (high mobility group) box DUF778 PF05608.12 AIM24084.1 - 0.15 12.4 1.8 0.18 12.2 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF778) DUF3106 PF11304.8 AIM24084.1 - 6.8 7.2 15.8 15 6.1 9.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3106) EAL PF00563.20 AIM24085.1 - 2.9e-68 229.9 0.1 4.2e-68 229.4 0.1 1.2 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AIM24085.1 - 3e-45 153.9 0.0 4.9e-45 153.2 0.0 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_9 PF13426.7 AIM24085.1 - 4.3e-10 39.8 0.1 9.8e-10 38.6 0.1 1.6 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 AIM24085.1 - 4.5e-07 30.1 0.0 2e-06 28.0 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 AIM24085.1 - 2.2e-06 27.7 0.0 8.5e-06 25.7 0.0 2.1 2 0 0 2 2 2 1 PAS fold GGDEF_2 PF17853.1 AIM24085.1 - 0.011 16.0 0.0 0.067 13.4 0.0 2.3 2 0 0 2 2 2 0 GGDEF-like domain PAS_8 PF13188.7 AIM24085.1 - 0.023 14.7 0.2 4.4 7.4 0.0 3.1 3 0 0 3 3 3 0 PAS domain PAS_10 PF13596.6 AIM24085.1 - 0.032 14.8 0.0 0.074 13.6 0.0 1.7 1 0 0 1 1 1 0 PAS domain ECH_1 PF00378.20 AIM24086.1 - 1.5e-17 63.8 0.1 1.8e-17 63.5 0.1 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AIM24086.1 - 9e-09 35.3 0.5 1.4e-08 34.7 0.5 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Glucosaminidase PF01832.20 AIM24086.1 - 0.033 14.7 0.0 0.056 14.0 0.0 1.7 1 1 0 1 1 1 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase Virul_fac_BrkB PF03631.15 AIM24087.1 - 6.9e-46 157.0 17.6 8.8e-46 156.6 17.6 1.0 1 0 0 1 1 1 1 Virulence factor BrkB Sugar_tr PF00083.24 AIM24088.1 - 1.1e-32 113.5 32.0 6.2e-24 84.7 7.7 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 AIM24088.1 - 1.1e-29 103.5 60.0 3.5e-16 59.1 25.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 AIM24088.1 - 0.61 8.6 39.8 0.047 12.2 18.6 3.6 2 1 1 3 3 3 0 MFS/sugar transport protein CDH PF02611.15 AIM24089.1 - 3.3e-87 291.8 0.0 3.7e-87 291.6 0.0 1.0 1 0 0 1 1 1 1 CDP-diacylglycerol pyrophosphatase AsmA PF05170.14 AIM24090.1 - 7.8e-140 467.5 0.0 9.1e-140 467.3 0.0 1.0 1 0 0 1 1 1 1 AsmA family AsmA_2 PF13502.6 AIM24090.1 - 5.5e-16 58.8 5.4 1.8e-15 57.1 2.6 2.7 3 0 0 3 3 3 1 AsmA-like C-terminal region DUF748 PF05359.11 AIM24090.1 - 0.00034 20.8 1.9 0.026 14.7 0.0 4.0 3 2 3 6 6 6 1 Domain of Unknown Function (DUF748) EAL PF00563.20 AIM24091.1 - 7.8e-31 107.4 0.4 9.9e-31 107.1 0.4 1.1 1 0 0 1 1 1 1 EAL domain PfkB PF00294.24 AIM24092.1 - 1.7e-66 224.6 0.0 2.1e-66 224.3 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase IlvN PF07991.12 AIM24093.1 - 1.2e-58 197.4 0.3 1.9e-58 196.7 0.3 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 AIM24093.1 - 1.1e-52 178.2 0.2 7.4e-27 94.4 0.0 2.3 2 0 0 2 2 2 2 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.19 AIM24093.1 - 0.00014 21.3 0.0 0.00028 20.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 AIM24093.1 - 0.0025 18.2 0.0 0.011 16.2 0.0 2.0 2 0 0 2 2 2 1 Putative NAD(P)-binding AdoHcyase_NAD PF00670.21 AIM24093.1 - 0.0055 16.8 0.1 0.011 15.8 0.1 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ApbA PF02558.16 AIM24093.1 - 0.02 14.5 0.0 0.039 13.6 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA LysR_substrate PF03466.20 AIM24094.1 - 3.7e-38 131.0 0.6 3.7e-38 131.0 0.6 1.5 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AIM24094.1 - 2.3e-21 75.5 0.2 4.6e-21 74.5 0.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AIM24094.1 - 1.1e-06 28.3 0.1 2.5e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain Mga PF05043.13 AIM24094.1 - 0.013 16.1 0.4 0.39 11.3 0.0 2.2 1 1 1 2 2 2 0 Mga helix-turn-helix domain MarR PF01047.22 AIM24094.1 - 0.013 15.4 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_28 PF13518.6 AIM24094.1 - 0.037 14.2 0.0 0.087 13.0 0.0 1.7 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.6 AIM24094.1 - 0.04 13.5 0.1 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 AIM24094.1 - 0.042 13.7 0.0 0.21 11.5 0.0 2.1 2 0 0 2 2 2 0 Homeodomain-like domain Fe_dep_repress PF01325.19 AIM24094.1 - 0.13 12.5 0.0 0.45 10.7 0.0 1.8 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain PrpR_N PF06506.11 AIM24094.1 - 0.13 11.8 0.0 0.41 10.2 0.0 1.7 2 0 0 2 2 2 0 Propionate catabolism activator DUF2461 PF09365.10 AIM24095.1 - 2.2e-45 155.2 0.1 2.5e-45 155.0 0.1 1.0 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) Gag_p15 PF08723.10 AIM24096.1 - 0.13 12.5 0.1 0.21 11.8 0.1 1.3 1 0 0 1 1 1 0 Gag protein p15 Tad PF13400.6 AIM24096.1 - 9.1 6.7 26.7 0.086 13.2 10.6 3.0 2 1 1 3 3 3 0 Putative Flp pilus-assembly TadE/G-like PALP PF00291.25 AIM24097.1 - 1.3e-78 264.4 3.5 1.7e-78 264.0 3.5 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 AIM24097.1 - 1.8e-57 191.1 0.0 8.7e-29 99.1 0.0 2.4 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase TraT PF05818.12 AIM24097.1 - 0.098 12.3 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein ILVD_EDD PF00920.21 AIM24098.1 - 6.7e-219 727.8 2.8 7.6e-219 727.6 2.8 1.0 1 0 0 1 1 1 1 Dehydratase family DUF570 PF04489.13 AIM24098.1 - 0.22 10.1 0.0 0.32 9.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF570) Ribosomal_S27 PF01599.19 AIM24098.1 - 0.67 10.2 3.1 34 4.7 0.5 3.2 3 0 0 3 3 3 0 Ribosomal protein S27a Aminotran_4 PF01063.19 AIM24099.1 - 6.7e-50 170.0 0.0 7.8e-50 169.8 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV G-gamma PF00631.22 AIM24099.1 - 0.027 14.5 0.0 0.051 13.6 0.0 1.4 1 0 0 1 1 1 0 GGL domain ACT_5 PF13710.6 AIM24100.1 - 1.4e-24 85.7 0.0 1.7e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 AIM24100.1 - 0.00019 21.9 0.0 0.00022 21.7 0.0 1.1 1 0 0 1 1 1 1 ACT domain TPP_enzyme_N PF02776.18 AIM24101.1 - 5.3e-55 185.7 0.3 5.3e-55 185.7 0.3 2.7 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 AIM24101.1 - 1.3e-49 167.9 1.2 2.4e-49 167.0 0.0 2.1 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 AIM24101.1 - 2.1e-44 150.6 0.7 4.3e-44 149.6 0.4 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 AIM24101.1 - 0.081 12.7 1.1 0.17 11.6 1.1 1.5 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg CO_dh PF02552.16 AIM24101.1 - 0.095 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit MFS_1 PF07690.16 AIM24102.1 - 2.6e-47 161.5 59.4 2.2e-38 132.1 36.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AIM24102.1 - 3.7e-36 124.9 26.8 7.9e-26 90.9 10.0 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 AIM24102.1 - 1.4e-06 27.4 21.5 0.00061 18.7 1.2 3.1 1 1 0 2 2 2 2 MFS_1 like family MFS_5 PF05631.14 AIM24102.1 - 6.1e-05 22.1 6.6 0.00055 19.0 1.3 2.3 2 1 0 2 2 2 2 Sugar-tranasporters, 12 TM Mg_chelatase PF01078.21 AIM24103.1 - 3.5e-90 300.9 0.0 5.1e-90 300.4 0.0 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ChlI PF13541.6 AIM24103.1 - 1.9e-44 150.4 0.0 4.9e-44 149.0 0.0 1.7 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase Mg_chelatase_C PF13335.6 AIM24103.1 - 2e-28 98.8 3.8 4.1e-28 97.9 3.8 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI C-terminal MCM PF00493.23 AIM24103.1 - 1.2e-13 50.7 0.0 4.8e-11 42.2 0.0 2.3 2 0 0 2 2 2 2 MCM P-loop domain AAA_5 PF07728.14 AIM24103.1 - 2.4e-11 43.8 0.3 2.9e-10 40.3 0.1 2.5 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 AIM24103.1 - 1.9e-07 31.0 0.0 0.0016 18.1 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_32 PF13654.6 AIM24103.1 - 4.7e-06 25.7 0.1 0.00034 19.5 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA PF00004.29 AIM24103.1 - 0.0001 22.7 0.8 0.0028 18.1 0.6 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 AIM24103.1 - 0.00022 21.0 0.0 0.03 14.1 0.0 3.1 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activ_2 PF14532.6 AIM24103.1 - 0.00075 19.6 0.1 0.0069 16.5 0.1 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.6 AIM24103.1 - 0.00079 19.7 0.1 0.0047 17.2 0.0 2.3 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.6 AIM24103.1 - 0.0031 17.9 0.0 0.0031 17.9 0.0 3.2 4 1 0 4 4 4 1 AAA ATPase domain AAA_7 PF12775.7 AIM24103.1 - 0.0058 16.2 0.0 0.032 13.8 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 AIM24103.1 - 0.0072 16.5 0.8 0.077 13.2 0.0 2.8 3 1 0 3 3 3 1 AAA domain AAA_28 PF13521.6 AIM24103.1 - 0.013 15.8 0.1 0.14 12.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 AIM24103.1 - 0.014 15.1 0.0 0.057 13.1 0.1 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_30 PF13604.6 AIM24103.1 - 0.015 15.1 0.0 0.045 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 AIM24103.1 - 0.039 13.7 0.1 0.097 12.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 AIM24103.1 - 0.04 13.6 0.0 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AIM24103.1 - 0.051 13.2 0.4 0.16 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 AIM24103.1 - 0.06 13.7 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 AIM24103.1 - 0.061 12.5 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain TniB PF05621.11 AIM24103.1 - 0.076 12.4 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein ABC_tran PF00005.27 AIM24103.1 - 0.084 13.4 0.2 0.24 11.9 0.0 1.8 2 0 0 2 2 1 0 ABC transporter Parvo_NS1 PF01057.17 AIM24103.1 - 0.25 10.4 0.1 2.9 6.9 0.0 2.0 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 DUF413 PF04219.12 AIM24104.1 - 8.1e-39 131.5 0.5 9.5e-39 131.3 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF LysR_substrate PF03466.20 AIM24105.1 - 1.1e-20 74.0 1.4 1.5e-20 73.5 1.4 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM24105.1 - 1.3e-20 73.0 1.8 2.2e-20 72.3 0.9 1.9 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family Asp_Glu_race PF01177.22 AIM24106.1 - 1.9e-25 90.1 0.0 2.5e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase TonB_dep_Rec PF00593.24 AIM24107.1 - 5.2e-49 168.4 36.5 5.2e-49 168.4 36.5 2.1 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 AIM24107.1 - 1.9e-28 99.2 1.5 5.5e-28 97.7 1.5 1.8 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain tRNA_U5-meth_tr PF05958.11 AIM24108.1 - 6.2e-191 634.0 0.1 7.1e-191 633.8 0.1 1.0 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_25 PF13649.6 AIM24108.1 - 3.4e-06 27.7 0.0 1.1e-05 26.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 AIM24108.1 - 7.4e-05 22.3 0.1 0.00016 21.2 0.1 1.5 1 0 0 1 1 1 1 Putative methyltransferase Cons_hypoth95 PF03602.15 AIM24108.1 - 0.00021 21.0 0.3 0.00077 19.1 0.3 1.8 1 1 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 AIM24108.1 - 0.00034 21.2 0.0 0.00096 19.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AIM24108.1 - 0.00035 20.1 0.1 0.00058 19.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 AIM24108.1 - 0.0005 19.7 0.0 0.00089 18.9 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 AIM24108.1 - 0.0041 16.6 0.2 0.0083 15.5 0.1 1.4 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 AIM24108.1 - 0.0085 15.9 0.1 0.017 14.9 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 AIM24108.1 - 0.01 15.6 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_12 PF08242.12 AIM24108.1 - 0.054 14.3 0.0 0.12 13.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.11 AIM24108.1 - 0.071 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) DREV PF05219.12 AIM24108.1 - 0.15 11.2 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase DUF1422 PF07226.11 AIM24109.1 - 2.5e-56 188.5 1.0 2.8e-56 188.4 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1422) DUF4658 PF15555.6 AIM24109.1 - 0.11 12.6 2.1 9 6.4 0.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4658) TetR_N PF00440.23 AIM24110.1 - 2.2e-07 30.6 1.7 2.6e-07 30.3 0.1 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_Tnp_1 PF01527.20 AIM24110.1 - 0.038 14.3 0.0 11 6.4 0.0 3.2 3 0 0 3 3 3 0 Transposase TetR_C_15 PF17918.1 AIM24110.1 - 0.14 12.9 5.9 0.048 14.4 2.8 1.8 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Pyr_redox_2 PF07992.14 AIM24111.1 - 1.1e-57 195.5 0.0 1.5e-57 195.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 AIM24111.1 - 4.7e-30 104.1 0.3 2.5e-29 101.7 0.4 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 AIM24111.1 - 9.2e-20 71.0 3.3 1e-17 64.5 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AIM24111.1 - 1.5e-08 34.2 0.5 0.00023 20.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AIM24111.1 - 1.4e-06 27.9 0.0 2.4e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AIM24111.1 - 1.5e-06 28.3 0.8 9.4e-05 22.6 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 AIM24111.1 - 3.2e-05 23.3 1.1 0.0024 17.2 0.4 2.8 3 0 0 3 3 3 1 FAD binding domain FAD_binding_2 PF00890.24 AIM24111.1 - 3.5e-05 23.1 1.2 9.9e-05 21.6 1.1 1.8 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 AIM24111.1 - 5.9e-05 22.0 3.6 0.026 13.3 1.6 3.0 3 1 0 3 3 3 2 HI0933-like protein K_oxygenase PF13434.6 AIM24111.1 - 6.5e-05 22.2 0.0 0.00013 21.2 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 AIM24111.1 - 7e-05 22.2 0.7 0.0002 20.7 0.3 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 AIM24111.1 - 0.00023 21.2 0.8 2.5 8.1 0.0 3.2 2 1 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.22 AIM24111.1 - 0.00049 19.3 3.5 0.2 10.7 1.6 3.7 3 1 0 3 3 3 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 AIM24111.1 - 0.0012 18.2 0.0 0.022 14.1 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 AIM24111.1 - 0.0014 18.0 2.7 0.86 8.8 0.0 3.7 4 0 0 4 4 4 1 Flavin containing amine oxidoreductase 3HCDH_N PF02737.18 AIM24111.1 - 0.0075 16.2 0.9 1.8 8.4 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 AIM24111.1 - 0.012 15.2 4.3 0.032 13.8 0.1 3.2 4 0 0 4 4 4 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 AIM24111.1 - 0.082 12.3 0.0 0.37 10.1 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain LysR_substrate PF03466.20 AIM24112.1 - 1.8e-53 181.0 0.4 2.4e-53 180.6 0.4 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AIM24112.1 - 2.3e-21 75.5 0.4 9.1e-21 73.6 0.2 2.0 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AIM24112.1 - 0.0072 16.1 0.1 0.02 14.7 0.1 1.8 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain Redoxin PF08534.10 AIM24113.1 - 7e-34 116.7 0.7 1.7e-33 115.4 0.0 1.9 2 1 1 3 3 3 1 Redoxin Glutaredoxin PF00462.24 AIM24113.1 - 3.9e-20 71.8 0.3 1.6e-19 69.8 0.0 2.2 3 0 0 3 3 3 1 Glutaredoxin AhpC-TSA PF00578.21 AIM24113.1 - 1.6e-10 41.0 0.2 9.9e-10 38.4 0.0 2.1 2 1 0 2 2 2 1 AhpC/TSA family GST_N_3 PF13417.6 AIM24113.1 - 2.1e-07 31.2 0.0 4.1e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AIM24113.1 - 0.00014 22.1 0.0 0.00031 21.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF836 PF05768.14 AIM24113.1 - 0.00027 21.3 0.0 0.00083 19.7 0.0 1.9 2 0 0 2 2 2 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 AIM24113.1 - 0.03 14.8 0.0 0.1 13.0 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin-like domain Pyr_redox_2 PF07992.14 AIM24114.1 - 2.3e-39 135.4 0.1 2.9e-39 135.0 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 AIM24114.1 - 1.2e-18 67.4 0.0 2.1e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_3 PF13738.6 AIM24114.1 - 2.1e-09 37.1 0.0 4.1e-06 26.3 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AIM24114.1 - 4.8e-09 35.8 1.3 6.9e-09 35.3 0.0 1.9 3 0 0 3 3 3 1 Glucose inhibited division protein A Pyr_redox PF00070.27 AIM24114.1 - 1.3e-05 25.7 2.1 0.00012 22.5 0.1 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 AIM24114.1 - 8.5e-05 21.9 0.1 0.0089 15.2 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 AIM24114.1 - 0.0073 15.9 1.1 0.018 14.7 0.5 1.8 2 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 AIM24114.1 - 0.0076 15.0 0.5 0.52 9.0 0.8 2.3 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 AIM24114.1 - 0.022 13.8 2.4 0.1 11.6 1.7 2.1 1 1 1 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 AIM24114.1 - 0.11 11.5 0.1 0.25 10.3 0.1 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 AIM24114.1 - 0.24 10.7 4.1 1.4 8.1 0.7 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 AIM24114.1 - 0.32 10.2 7.1 29 3.8 0.1 3.8 3 1 1 4 4 4 0 FAD binding domain HicB PF05534.12 AIM24116.1 - 6.7e-13 48.3 0.0 9e-13 47.8 0.0 1.2 1 0 0 1 1 1 1 HicB family ParD PF09386.10 AIM24116.1 - 0.065 13.6 0.0 0.19 12.2 0.0 1.6 2 0 0 2 2 2 0 Antitoxin ParD Lyase_1 PF00206.20 AIM24117.1 - 8.2e-98 327.6 1.2 1.1e-97 327.2 0.1 1.8 3 0 0 3 3 3 1 Lyase ASL_C2 PF14698.6 AIM24117.1 - 9.8e-24 83.9 0.2 3e-23 82.4 0.0 2.0 2 0 0 2 2 2 1 Argininosuccinate lyase C-terminal SBP_bac_8 PF13416.6 AIM24117.1 - 0.0036 17.1 0.1 0.47 10.2 0.2 2.2 2 0 0 2 2 2 2 Bacterial extracellular solute-binding protein ADSL_C PF10397.9 AIM24117.1 - 0.1 13.1 1.0 1.5 9.4 0.0 2.8 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminus Arginosuc_synth PF00764.19 AIM24118.1 - 7.2e-144 479.8 0.0 8.3e-144 479.6 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 AIM24118.1 - 0.037 13.5 0.0 0.065 12.7 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC AA_kinase PF00696.28 AIM24119.1 - 6e-39 134.1 2.9 6.7e-39 133.9 2.9 1.0 1 0 0 1 1 1 1 Amino acid kinase family Smr PF01713.21 AIM24119.1 - 0.014 15.7 0.0 0.051 13.9 0.0 2.0 2 1 0 2 2 2 0 Smr domain YAcAr PF10686.9 AIM24119.1 - 0.022 14.7 0.0 0.097 12.6 0.0 2.1 1 1 1 2 2 2 0 YspA, cpYpsA-related SLOG family Semialdhyde_dh PF01118.24 AIM24120.1 - 5e-34 117.3 0.0 9.1e-34 116.5 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.18 AIM24120.1 - 6.3e-17 62.2 0.0 1e-16 61.6 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain NAD_binding_10 PF13460.6 AIM24120.1 - 0.00034 20.6 0.2 0.00053 19.9 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 AIM24120.1 - 0.0029 17.1 0.1 0.0046 16.5 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GFO_IDH_MocA PF01408.22 AIM24120.1 - 0.0061 17.4 0.1 0.017 15.9 0.1 1.8 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.20 AIM24120.1 - 0.026 14.7 0.0 0.049 13.7 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.13 AIM24120.1 - 0.12 11.9 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family Peptidase_M20 PF01546.28 AIM24121.1 - 1.9e-35 122.5 0.0 2.5e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AIM24121.1 - 5.6e-25 87.4 0.0 9.5e-25 86.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 AIM24121.1 - 0.00095 18.9 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 DUF3088 PF11287.8 AIM24121.1 - 0.018 14.8 0.0 0.23 11.3 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3088) Peptidase_M42 PF05343.14 AIM24121.1 - 0.049 12.6 0.0 0.091 11.8 0.0 1.4 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase PEPcase PF00311.17 AIM24122.1 - 2.2e-291 968.7 0.0 2.8e-291 968.3 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase PEPcase_2 PF14010.6 AIM24122.1 - 8.6e-05 21.2 0.0 0.00015 20.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase MTHFR PF02219.17 AIM24123.1 - 5.1e-109 364.0 0.0 5.8e-109 363.8 0.0 1.0 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Homoserine_dh PF00742.19 AIM24124.1 - 3e-43 147.7 0.0 5.2e-43 147.0 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase AA_kinase PF00696.28 AIM24124.1 - 1.1e-42 146.3 0.0 1.6e-42 145.7 0.0 1.3 1 0 0 1 1 1 1 Amino acid kinase family NAD_binding_3 PF03447.16 AIM24124.1 - 1.3e-21 77.4 0.0 4e-21 75.8 0.0 1.9 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Cys_Met_Meta_PP PF01053.20 AIM24125.1 - 2.4e-141 470.7 0.0 2.8e-141 470.5 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 AIM24125.1 - 1e-06 28.2 0.0 1.6e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 AIM24125.1 - 2e-05 23.7 0.0 3.1e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V MetJ PF01340.20 AIM24126.1 - 2.4e-58 194.1 0.0 2.7e-58 194.0 0.0 1.0 1 0 0 1 1 1 1 Met Apo-repressor, MetJ SWI2_SNF2 PF18766.1 AIM24126.1 - 0.035 13.8 0.0 0.039 13.6 0.0 1.1 1 0 0 1 1 1 0 SWI2/SNF2 ATPase AphA_like PF14557.6 AIM24126.1 - 0.092 12.5 0.0 0.097 12.4 0.0 1.1 1 0 0 1 1 1 0 Putative AphA-like transcriptional regulator Ribosomal_L31 PF01197.18 AIM24127.1 - 4.2e-30 103.8 0.1 4.7e-30 103.6 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L31 PriA_3primeBD PF17764.1 AIM24128.1 - 1.1e-29 102.1 0.0 2.4e-29 101.1 0.0 1.6 1 0 0 1 1 1 1 3′ DNA-binding domain (3′BD) PriA_C PF18074.1 AIM24128.1 - 9.1e-19 68.1 0.0 4.5e-18 65.9 0.0 2.3 2 0 0 2 2 2 1 Primosomal protein N C-terminal domain DEAD PF00270.29 AIM24128.1 - 4e-14 52.8 0.0 7.4e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 AIM24128.1 - 8.9e-13 48.6 0.0 1.6e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 AIM24128.1 - 1.8e-11 44.3 0.0 7e-06 26.4 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain PriA_CRR PF18319.1 AIM24128.1 - 3.3e-08 33.4 16.3 3.3e-08 33.4 16.3 2.9 3 0 0 3 3 3 1 PriA DNA helicase Cys-rich region (CRR) domain AAA_30 PF13604.6 AIM24128.1 - 0.0066 16.2 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain TrwB_AAD_bind PF10412.9 AIM24128.1 - 0.015 14.2 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain zinc-ribbons_6 PF07191.12 AIM24128.1 - 0.016 15.1 7.7 0.035 14.1 7.7 1.5 1 0 0 1 1 1 0 zinc-ribbons AAA_19 PF13245.6 AIM24128.1 - 0.053 13.9 0.0 0.17 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 AIM24128.1 - 0.13 12.5 0.0 0.67 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 AIM24128.1 - 0.17 11.2 0.0 0.34 10.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin HypA PF01155.19 AIM24128.1 - 9.7 6.3 10.9 73 3.4 10.9 2.2 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Peripla_BP_3 PF13377.6 AIM24129.1 - 3.5e-46 157.6 0.0 1.1e-45 156.0 0.0 1.7 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 AIM24129.1 - 1e-37 130.1 0.1 1.4e-37 129.7 0.1 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 AIM24129.1 - 4.4e-18 64.8 0.4 9.2e-18 63.8 0.4 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 AIM24129.1 - 4.4e-17 62.5 0.0 1.6e-16 60.7 0.0 1.8 1 1 0 1 1 1 1 Periplasmic binding protein domain HTH_Tnp_ISL3 PF13542.6 AIM24129.1 - 0.00092 18.6 0.1 0.0023 17.3 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_Crp_2 PF13545.6 AIM24129.1 - 0.0055 16.7 0.1 0.039 13.9 0.0 2.3 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_AraC PF00165.23 AIM24129.1 - 0.008 16.3 0.0 4.7 7.4 0.0 2.4 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix proteins, AraC family ANF_receptor PF01094.28 AIM24129.1 - 0.019 14.0 0.0 0.036 13.2 0.0 1.4 1 0 0 1 1 1 0 Receptor family ligand binding region HTH_23 PF13384.6 AIM24129.1 - 0.021 14.6 0.3 1.3 8.9 0.0 2.9 3 0 0 3 3 3 0 Homeodomain-like domain HTH_6 PF01418.17 AIM24129.1 - 0.025 14.5 0.1 1.6 8.7 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family MarR_2 PF12802.7 AIM24129.1 - 0.03 14.2 0.2 3.3 7.7 0.0 2.7 1 1 1 2 2 2 0 MarR family HTH_38 PF13936.6 AIM24129.1 - 0.036 13.8 0.0 1.4 8.7 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_3 PF01381.22 AIM24129.1 - 0.069 13.2 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix HTH_24 PF13412.6 AIM24129.1 - 0.12 11.9 0.1 0.45 10.1 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_29 PF13551.6 AIM24129.1 - 0.13 12.3 0.2 8.8 6.4 0.0 2.5 2 0 0 2 2 2 0 Winged helix-turn helix Sigma54_DBD PF04552.13 AIM24129.1 - 0.2 11.4 0.2 0.35 10.6 0.2 1.4 1 0 0 1 1 1 0 Sigma-54, DNA binding domain SPOR PF05036.13 AIM24130.1 - 5.1e-19 68.4 0.1 1.4e-18 67.0 0.0 1.8 2 0 0 2 2 2 1 Sporulation related domain TFIIA PF03153.13 AIM24130.1 - 0.014 15.4 25.2 0.017 15.2 25.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SOG2 PF10428.9 AIM24130.1 - 1.3 8.2 11.1 1.4 8.0 11.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein TonB_N PF16031.5 AIM24130.1 - 4.2 7.9 40.4 0.19 12.3 32.8 2.2 1 1 0 2 2 2 0 TonB polyproline region Proteasome PF00227.26 AIM24131.1 - 7e-22 77.8 0.3 1.2e-21 77.1 0.3 1.4 1 1 0 1 1 1 1 Proteasome subunit PspC PF04024.12 AIM24131.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 PspC domain AAA_2 PF07724.14 AIM24132.1 - 1.3e-50 171.8 0.6 1.5e-41 142.4 0.1 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 AIM24132.1 - 5.9e-17 62.3 0.1 3.6e-07 30.7 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AIM24132.1 - 1.1e-07 31.9 0.6 4.7e-06 26.7 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 AIM24132.1 - 1.7e-07 31.6 0.0 0.0001 22.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain ClpB_D2-small PF10431.9 AIM24132.1 - 9.9e-07 28.7 1.0 3.1e-06 27.1 0.1 2.3 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.6 AIM24132.1 - 7.4e-06 26.4 0.8 9.6e-05 22.8 0.2 2.5 2 1 0 2 2 2 1 AAA ATPase domain MCM PF00493.23 AIM24132.1 - 5.6e-05 22.4 0.1 0.0032 16.6 0.0 2.2 2 0 0 2 2 2 1 MCM P-loop domain Mg_chelatase PF01078.21 AIM24132.1 - 9.9e-05 21.8 0.7 0.0028 17.1 0.3 3.2 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 AIM24132.1 - 0.00052 19.8 0.2 0.037 13.8 0.0 2.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 AIM24132.1 - 0.00069 19.4 0.1 0.012 15.3 0.0 2.5 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_18 PF13238.6 AIM24132.1 - 0.0012 19.4 0.1 0.0046 17.5 0.0 2.1 2 0 0 2 2 1 1 AAA domain TniB PF05621.11 AIM24132.1 - 0.0016 17.8 0.5 0.0071 15.8 0.1 2.1 2 1 0 2 2 2 1 Bacterial TniB protein TIP49 PF06068.13 AIM24132.1 - 0.0019 17.5 0.9 0.0046 16.2 0.1 1.9 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_28 PF13521.6 AIM24132.1 - 0.0027 18.0 0.6 0.02 15.1 0.0 2.7 3 1 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 AIM24132.1 - 0.0091 15.7 0.0 0.024 14.4 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 AIM24132.1 - 0.012 15.8 0.0 0.026 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 AIM24132.1 - 0.016 15.0 0.1 1 9.1 0.0 2.5 3 0 0 3 3 2 0 DEAD/DEAH box helicase AAA_7 PF12775.7 AIM24132.1 - 0.035 13.6 0.0 0.087 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region ATP-synt_ab PF00006.25 AIM24132.1 - 0.036 13.7 0.2 0.34 10.6 0.0 2.1 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.6 AIM24132.1 - 0.04 13.6 0.2 0.14 11.9 0.1 2.0 2 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 AIM24132.1 - 0.045 12.8 0.0 0.097 11.7 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 AIM24132.1 - 0.047 14.2 0.0 0.15 12.6 0.0 1.8 1 1 0 1 1 1 0 ABC transporter RHH_1 PF01402.21 AIM24132.1 - 0.052 13.5 0.5 21 5.2 0.2 3.9 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family ResIII PF04851.15 AIM24132.1 - 0.056 13.5 0.5 1.3 9.0 0.0 2.7 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit NACHT PF05729.12 AIM24132.1 - 0.059 13.3 0.1 2.3 8.1 0.0 2.6 2 1 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.12 AIM24132.1 - 0.065 12.5 0.0 0.18 11.0 0.0 1.8 2 0 0 2 2 1 0 Zeta toxin TsaE PF02367.17 AIM24132.1 - 0.07 13.1 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 AIM24132.1 - 0.071 12.7 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 AIM24132.1 - 0.09 12.7 0.0 0.25 11.2 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase NTPase_1 PF03266.15 AIM24132.1 - 0.12 12.3 0.6 3.5 7.5 0.0 2.3 2 0 0 2 2 2 0 NTPase AAA_19 PF13245.6 AIM24132.1 - 0.71 10.2 2.8 4.2 7.7 2.8 2.2 1 1 0 1 1 1 0 AAA domain UbiA PF01040.18 AIM24133.1 - 3e-39 134.8 10.6 4.6e-39 134.2 10.6 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF4231 PF14015.6 AIM24133.1 - 2.7 8.5 6.7 27 5.3 0.5 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF4231) RraA-like PF03737.15 AIM24134.1 - 5.5e-35 120.7 0.1 6.1e-35 120.6 0.1 1.0 1 0 0 1 1 1 1 Aldolase/RraA baeRF_family5 PF18846.1 AIM24134.1 - 0.15 12.3 0.0 0.23 11.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 5 ZapB PF06005.12 AIM24135.1 - 9e-28 96.5 10.6 1e-27 96.4 10.6 1.0 1 0 0 1 1 1 1 Cell division protein ZapB Seryl_tRNA_N PF02403.22 AIM24135.1 - 0.0005 20.3 5.6 0.00065 19.9 5.6 1.2 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain CtIP_N PF10482.9 AIM24135.1 - 0.00076 19.5 7.5 0.077 13.0 2.5 2.0 2 0 0 2 2 2 2 Tumour-suppressor protein CtIP N-terminal domain PspA_IM30 PF04012.12 AIM24135.1 - 0.0014 18.3 5.9 0.0015 18.2 5.9 1.0 1 0 0 1 1 1 1 PspA/IM30 family Cnn_1N PF07989.11 AIM24135.1 - 0.0047 17.0 5.0 0.0059 16.7 5.0 1.3 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 UPF0242 PF06785.11 AIM24135.1 - 0.0062 16.7 5.7 0.0068 16.5 5.7 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus HemX PF04375.14 AIM24135.1 - 0.007 15.7 4.8 0.0073 15.6 4.8 1.0 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase Leu_zip PF15294.6 AIM24135.1 - 0.01 15.4 3.9 0.011 15.2 3.9 1.1 1 0 0 1 1 1 0 Leucine zipper HAUS-augmin3 PF14932.6 AIM24135.1 - 0.011 15.3 6.4 0.013 15.1 6.4 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF3450 PF11932.8 AIM24135.1 - 0.02 14.2 5.6 0.023 14.0 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) NRBF2 PF08961.10 AIM24135.1 - 0.024 14.2 2.2 0.027 14.1 2.2 1.1 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator DUF773 PF05600.12 AIM24135.1 - 0.024 13.4 3.0 0.028 13.2 3.0 1.0 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 KASH_CCD PF14662.6 AIM24135.1 - 0.026 14.3 7.7 0.027 14.3 7.7 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF4757 PF15949.5 AIM24135.1 - 0.027 15.0 3.3 0.034 14.6 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4757) DHR10 PF18595.1 AIM24135.1 - 0.027 14.5 8.4 0.033 14.2 8.4 1.1 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Herpes_UL6 PF01763.16 AIM24135.1 - 0.028 12.9 2.5 0.03 12.9 2.5 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like MCC-bdg_PDZ PF10506.9 AIM24135.1 - 0.039 14.0 2.7 0.066 13.2 1.6 2.0 1 1 1 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Tropomyosin_1 PF12718.7 AIM24135.1 - 0.055 13.6 9.2 0.21 11.7 9.2 1.7 1 1 0 1 1 1 0 Tropomyosin like HALZ PF02183.18 AIM24135.1 - 0.064 13.5 7.9 0.6 10.4 0.2 2.8 3 0 0 3 3 3 0 Homeobox associated leucine zipper YabA PF06156.13 AIM24135.1 - 0.084 13.5 8.1 0.43 11.2 8.1 1.8 1 1 0 1 1 1 0 Initiation control protein YabA V_ATPase_I PF01496.19 AIM24135.1 - 0.085 10.8 2.6 0.091 10.7 2.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6_N PF17675.1 AIM24135.1 - 0.12 12.9 7.7 0.13 12.8 7.7 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region Uso1_p115_C PF04871.13 AIM24135.1 - 0.16 12.4 6.3 0.18 12.1 6.3 1.0 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region bZIP_1 PF00170.21 AIM24135.1 - 0.21 11.7 6.9 3 8.0 0.5 2.5 1 1 1 2 2 2 0 bZIP transcription factor FlaC_arch PF05377.11 AIM24135.1 - 0.23 11.9 6.4 0.61 10.5 2.8 2.1 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) dCache_2 PF08269.11 AIM24135.1 - 0.3 10.2 3.3 0.35 10.0 3.3 1.0 1 0 0 1 1 1 0 Cache domain DivIC PF04977.15 AIM24135.1 - 0.31 10.8 8.9 0.51 10.1 2.2 2.2 1 1 1 2 2 2 0 Septum formation initiator bZIP_2 PF07716.15 AIM24135.1 - 0.46 10.6 8.5 0.8 9.8 1.3 2.7 2 1 1 3 3 3 0 Basic region leucine zipper GIT_CC PF16559.5 AIM24135.1 - 0.54 10.2 8.2 1.6 8.7 6.9 2.1 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Spc24 PF08286.11 AIM24135.1 - 1.3 9.3 6.9 3.2 8.1 6.9 1.6 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DUF5595 PF18077.1 AIM24135.1 - 1.9 8.6 6.5 1.2 9.2 1.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5595) MIP PF00230.20 AIM24136.1 - 1.6e-70 237.4 12.5 1.9e-70 237.1 12.5 1.0 1 0 0 1 1 1 1 Major intrinsic protein TauE PF01925.19 AIM24136.1 - 4.6 6.8 27.3 7.8 6.1 7.7 2.9 1 1 1 2 2 2 0 Sulfite exporter TauE/SafE FGGY_N PF00370.21 AIM24137.1 - 1.6e-83 280.0 0.1 2.1e-83 279.6 0.1 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 AIM24137.1 - 3.1e-62 209.8 0.2 1.4e-61 207.7 0.2 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FBPase_glpX PF03320.13 AIM24138.1 - 5.9e-134 445.8 6.6 6.7e-134 445.6 6.6 1.0 1 0 0 1 1 1 1 Bacterial fructose-1,6-bisphosphatase, glpX-encoded MFS_1 PF07690.16 AIM24139.1 - 4.8e-36 124.4 54.2 4.8e-36 124.4 54.2 1.7 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 AIM24139.1 - 6.4e-09 35.2 12.3 6.4e-09 35.2 12.3 2.6 1 1 1 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 AIM24139.1 - 2.4e-06 26.3 6.2 4.1e-06 25.5 6.2 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 AIM24139.1 - 0.0003 19.3 13.5 0.0003 19.3 13.5 1.8 1 1 0 2 2 2 1 Transmembrane secretion effector DUF2530 PF10745.9 AIM24139.1 - 0.014 15.6 1.1 0.014 15.6 1.1 4.2 4 1 2 6 6 6 0 Protein of unknown function (DUF2530) HTH_11 PF08279.12 AIM24140.1 - 1.8e-05 24.6 0.0 3.9e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 HTH domain PadR PF03551.14 AIM24140.1 - 6.7e-05 22.8 0.1 0.00012 22.0 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family MarR PF01047.22 AIM24140.1 - 0.00054 19.8 0.1 0.0011 18.8 0.1 1.4 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 AIM24140.1 - 0.00085 19.2 0.9 0.0017 18.2 0.1 1.9 2 0 0 2 2 2 1 MarR family HTH_20 PF12840.7 AIM24140.1 - 0.00088 19.3 1.2 0.0012 18.8 0.2 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain Fe_dep_repress PF01325.19 AIM24140.1 - 0.0014 18.8 0.0 0.0024 18.0 0.0 1.4 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_24 PF13412.6 AIM24140.1 - 0.0035 16.9 0.0 0.0066 16.0 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 AIM24140.1 - 0.0064 16.3 0.4 0.013 15.3 0.4 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family DUF2250 PF10007.9 AIM24140.1 - 0.0088 16.1 0.1 0.022 14.9 0.1 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) HTH_DeoR PF08220.12 AIM24140.1 - 0.019 14.7 0.0 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain TrmB PF01978.19 AIM24140.1 - 0.038 13.9 0.0 0.067 13.1 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_13 PF11972.8 AIM24140.1 - 0.064 13.3 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain Rrf2 PF02082.20 AIM24140.1 - 0.071 13.5 0.1 0.13 12.6 0.1 1.4 1 0 0 1 1 1 0 Transcriptional regulator HTH_27 PF13463.6 AIM24140.1 - 0.1 13.1 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_34 PF13601.6 AIM24140.1 - 0.11 12.7 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_9 PF08221.11 AIM24140.1 - 0.15 12.2 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain NAD_binding_1 PF00175.21 AIM24141.1 - 1e-18 68.0 0.0 1.5e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 AIM24141.1 - 2.8e-07 30.8 0.0 6.5e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 AIM24141.1 - 0.13 12.3 0.0 2.7 8.1 0.0 2.1 1 1 0 2 2 2 0 Ferric reductase NAD binding domain DUF805 PF05656.14 AIM24142.1 - 3e-22 79.0 6.4 3.7e-22 78.7 6.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF805) DUF1454 PF07305.12 AIM24143.1 - 6.7e-79 263.8 0.4 7.9e-79 263.5 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1454) TIM PF00121.18 AIM24144.1 - 1.1e-93 313.1 0.1 1.2e-93 313.0 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase TMP-TENI PF02581.17 AIM24144.1 - 0.0082 15.5 0.5 0.015 14.6 0.1 1.7 2 0 0 2 2 2 1 Thiamine monophosphate synthase SBP_bac_11 PF13531.6 AIM24145.1 - 6.6e-46 156.9 0.1 8.3e-46 156.6 0.1 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AIM24145.1 - 4.4e-18 66.3 2.4 5.8e-18 65.9 2.4 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 AIM24145.1 - 2.9e-09 37.2 0.6 9.5e-09 35.5 0.6 1.7 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AIM24145.1 - 4.7e-08 32.7 0.3 1e-07 31.7 0.2 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein PBP_like PF12727.7 AIM24145.1 - 0.0079 15.3 0.0 0.012 14.8 0.0 1.5 1 0 0 1 1 1 1 PBP superfamily domain PFK PF00365.20 AIM24146.1 - 4.1e-109 364.3 0.5 4.9e-109 364.0 0.5 1.1 1 0 0 1 1 1 1 Phosphofructokinase NAD_kinase PF01513.21 AIM24146.1 - 0.0009 18.5 0.0 0.0013 18.0 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase Peripla_BP_1 PF00532.21 AIM24146.1 - 0.032 13.7 0.0 0.059 12.8 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family DAGK_cat PF00781.24 AIM24146.1 - 0.11 12.1 0.3 0.37 10.4 0.0 1.9 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain Cation_efflux PF01545.21 AIM24147.1 - 1.1e-43 149.3 13.8 1.3e-43 149.0 13.8 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 AIM24147.1 - 4.2e-27 94.1 0.0 6.2e-27 93.5 0.0 1.2 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter LTXXQ PF07813.12 AIM24148.1 - 8.9e-21 74.6 12.9 8.9e-21 74.6 12.9 1.9 1 1 1 2 2 2 1 LTXXQ motif family protein Metal_resist PF13801.6 AIM24148.1 - 3.8e-09 36.8 9.0 3.8e-09 36.8 9.0 2.2 1 1 1 2 2 2 2 Heavy-metal resistance HBS1_N PF08938.10 AIM24148.1 - 0.22 11.8 0.2 0.22 11.8 0.2 2.2 1 1 1 2 2 2 0 HBS1 N-terminus YbgS PF13985.6 AIM24148.1 - 0.46 10.8 2.7 0.88 9.9 0.4 2.0 1 1 0 2 2 2 0 YbgS-like protein DUF668 PF05003.12 AIM24148.1 - 0.9 10.0 5.0 0.64 10.5 3.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF668) Response_reg PF00072.24 AIM24149.1 - 2.1e-30 105.2 0.2 3.8e-30 104.3 0.2 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AIM24149.1 - 4.7e-21 74.6 0.3 1.2e-20 73.4 0.0 1.8 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal FleQ PF06490.11 AIM24149.1 - 0.01 16.2 0.1 0.016 15.6 0.1 1.3 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ HATPase_c PF02518.26 AIM24150.1 - 4.8e-20 72.2 0.0 1.8e-19 70.3 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AIM24150.1 - 9e-14 51.3 3.7 9e-14 51.3 3.7 2.2 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain CpxA_peri PF16527.5 AIM24150.1 - 5.1e-11 43.1 0.0 1.3e-10 41.7 0.0 1.7 1 0 0 1 1 1 1 Two-component sensor protein CpxA, periplasmic domain HAMP PF00672.25 AIM24150.1 - 1.1e-09 38.5 0.6 3.9e-09 36.8 0.0 2.3 2 1 0 2 2 2 1 HAMP domain HATPase_c_3 PF13589.6 AIM24150.1 - 1.1e-05 25.3 0.0 2.2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AIM24150.1 - 0.00032 20.6 0.1 0.00064 19.7 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_5 PF14501.6 AIM24150.1 - 0.029 14.3 0.0 0.065 13.1 0.0 1.6 1 0 0 1 1 1 0 GHKL domain Innexin PF00876.18 AIM24150.1 - 0.22 10.8 0.2 9 5.5 0.1 2.1 2 0 0 2 2 2 0 Innexin SpoU_methylase PF00588.19 AIM24151.1 - 3.8e-34 117.9 0.0 4.3e-34 117.7 0.0 1.0 1 0 0 1 1 1 1 SpoU rRNA Methylase family Malate_DH PF12434.8 AIM24151.1 - 0.0039 17.2 0.1 0.0091 16.0 0.1 1.6 1 0 0 1 1 1 1 Malate dehydrogenase enzyme CHAD PF05235.14 AIM24152.1 - 3.4e-25 89.4 23.3 5.9e-25 88.6 23.3 1.3 1 0 0 1 1 1 1 CHAD domain HSCB_C PF07743.13 AIM24152.1 - 0.0086 16.5 3.5 2.6 8.6 1.7 2.9 2 0 0 2 2 2 2 HSCB C-terminal oligomerisation domain DUF4248 PF14053.6 AIM24152.1 - 0.39 10.8 2.6 1 9.5 0.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4248) DUF3313 PF11769.8 AIM24153.1 - 8.6e-49 165.9 2.3 1e-48 165.6 2.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3313) DUF4148 PF13663.6 AIM24153.1 - 0.45 10.7 2.5 20 5.4 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) MLTD_N PF06474.12 AIM24153.1 - 0.91 9.8 4.4 2.6 8.3 4.4 1.8 1 0 0 1 1 1 0 MltD lipid attachment motif SATase_N PF06426.14 AIM24154.1 - 3.2e-37 127.1 0.2 4.7e-37 126.6 0.2 1.2 1 0 0 1 1 1 1 Serine acetyltransferase, N-terminal Hexapep PF00132.24 AIM24154.1 - 4.3e-11 42.1 7.5 2.3e-09 36.6 0.9 2.6 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AIM24154.1 - 1e-05 25.1 11.3 0.00056 19.6 1.1 2.6 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase NAD_Gly3P_dh_C PF07479.14 AIM24155.1 - 1.3e-53 181.1 0.5 2.3e-53 180.3 0.5 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 AIM24155.1 - 5.4e-50 169.4 0.0 7.8e-50 168.9 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 AIM24155.1 - 8.8e-10 38.4 0.0 1.5e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 AIM24155.1 - 2.1e-05 25.0 0.0 9.7e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 AIM24155.1 - 2.4e-05 24.5 0.0 5.7e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.14 AIM24155.1 - 0.00023 20.8 0.0 0.0025 17.4 0.0 2.4 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 AIM24155.1 - 0.0011 18.9 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rossmann-like PF10727.9 AIM24155.1 - 0.0013 18.6 1.0 0.0021 17.9 0.2 1.8 2 0 0 2 2 2 1 Rossmann-like domain GIDA PF01134.22 AIM24155.1 - 0.0013 17.9 0.0 0.0022 17.2 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A TrkA_N PF02254.18 AIM24155.1 - 0.002 18.4 0.0 0.0094 16.2 0.0 2.2 2 0 0 2 2 2 1 TrkA-N domain ApbA_C PF08546.11 AIM24155.1 - 0.0067 16.6 0.0 0.057 13.6 0.0 2.3 3 0 0 3 3 3 1 Ketopantoate reductase PanE/ApbA C terminal NAD_binding_8 PF13450.6 AIM24155.1 - 0.0078 16.4 0.2 0.031 14.5 0.2 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AIM24155.1 - 0.015 14.5 0.0 0.028 13.6 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UIM PF02809.20 AIM24155.1 - 0.2 11.6 1.6 0.78 9.8 1.6 2.1 1 0 0 1 1 1 0 Ubiquitin interaction motif SecB PF02556.14 AIM24156.1 - 4.7e-58 195.1 0.4 5.9e-58 194.8 0.4 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit SecB Glutaredoxin PF00462.24 AIM24157.1 - 2.3e-23 82.2 0.0 2.7e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 AIM24157.1 - 1.2e-06 28.8 0.0 1.4e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AIM24157.1 - 0.00042 20.6 0.0 0.00051 20.3 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF836 PF05768.14 AIM24157.1 - 0.0016 18.8 0.0 0.0021 18.4 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) SH3BGR PF04908.15 AIM24157.1 - 0.0063 16.7 0.0 0.0095 16.1 0.0 1.3 1 1 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Thioredoxin_3 PF13192.6 AIM24157.1 - 0.0096 16.0 0.0 0.012 15.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_4 PF13462.6 AIM24157.1 - 0.066 13.4 0.2 10 6.2 0.2 2.0 1 1 1 2 2 2 0 Thioredoxin DUF99 PF01949.16 AIM24157.1 - 0.073 12.5 0.0 0.078 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF99 DSBA PF01323.20 AIM24157.1 - 0.095 12.5 0.0 1.8 8.3 0.0 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Rhodanese PF00581.20 AIM24158.1 - 4.8e-13 49.6 0.0 6.4e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain TspO_MBR PF03073.15 AIM24158.1 - 0.036 14.1 0.2 0.051 13.6 0.2 1.2 1 0 0 1 1 1 0 TspO/MBR family MNHE PF01899.16 AIM24158.1 - 0.07 12.9 0.0 0.074 12.8 0.0 1.2 1 0 0 1 1 1 0 Na+/H+ ion antiporter subunit CD34_antigen PF06365.12 AIM24158.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family Metalloenzyme PF01676.18 AIM24159.1 - 5.8e-85 284.6 0.0 6.7e-85 284.4 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.13 AIM24159.1 - 8.8e-82 273.7 0.0 1.2e-81 273.3 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Sulfatase PF00884.23 AIM24159.1 - 0.00078 18.9 0.0 0.0025 17.3 0.0 1.6 1 1 1 2 2 2 1 Sulfatase PglZ PF08665.12 AIM24159.1 - 0.19 11.8 0.1 0.33 11.0 0.1 1.3 1 0 0 1 1 1 0 PglZ domain Peptidase_M23 PF01551.22 AIM24160.1 - 3e-25 88.2 0.3 7.1e-25 87.0 0.3 1.6 1 0 0 1 1 1 1 Peptidase family M23 FliJ PF02050.16 AIM24160.1 - 0.21 11.8 57.4 0.97 9.7 20.3 2.7 2 1 0 2 2 2 0 Flagellar FliJ protein EzrA PF06160.12 AIM24160.1 - 2.3 6.3 31.0 0.15 10.2 11.6 2.1 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA PEARLI-4 PF05278.12 AIM24160.1 - 3.7 7.1 22.0 0.16 11.5 2.0 2.4 2 1 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) Polysacc_deac_2 PF04748.13 AIM24161.1 - 8.5e-76 253.9 1.4 1e-75 253.6 1.4 1.1 1 0 0 1 1 1 1 Divergent polysaccharide deacetylase ADH_N PF08240.12 AIM24162.1 - 2.7e-32 110.9 1.9 5.9e-32 109.8 1.9 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AIM24162.1 - 5.5e-28 97.5 0.0 9e-28 96.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 AIM24162.1 - 1e-08 34.9 0.1 2.8e-08 33.5 0.1 1.6 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 AIM24162.1 - 1.4e-06 29.4 0.0 2.8e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 AIM24162.1 - 0.0014 17.9 0.6 0.0023 17.3 0.6 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 AIM24162.1 - 0.0033 16.7 0.3 0.006 15.9 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 AIM24162.1 - 0.017 14.2 0.1 0.022 13.8 0.1 1.1 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 AIM24162.1 - 0.017 13.8 0.1 0.023 13.4 0.1 1.1 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 AIM24162.1 - 0.052 12.8 0.1 0.083 12.1 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AIM24162.1 - 0.095 12.0 0.7 0.13 11.6 0.7 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 AIM24162.1 - 0.2 12.2 1.2 0.47 11.1 0.3 2.1 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 AIM24162.1 - 0.47 10.0 2.4 0.37 10.3 0.1 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Aminotran_1_2 PF00155.21 AIM24163.1 - 6.9e-77 259.1 0.1 8e-77 258.8 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II SHMT PF00464.19 AIM24163.1 - 5e-05 22.1 0.1 0.00057 18.6 0.1 2.2 1 1 0 1 1 1 1 Serine hydroxymethyltransferase DegT_DnrJ_EryC1 PF01041.17 AIM24163.1 - 0.00022 20.7 0.3 0.00051 19.5 0.2 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 AIM24163.1 - 0.0015 17.6 0.0 0.0043 16.1 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 AIM24163.1 - 0.0059 15.9 0.8 0.014 14.7 0.8 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase HATPase_c_5 PF14501.6 AIM24163.1 - 0.021 14.7 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 GHKL domain Epimerase PF01370.21 AIM24164.1 - 5.7e-47 160.2 0.0 7.2e-47 159.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AIM24164.1 - 1.1e-22 80.9 0.1 2.4e-22 79.8 0.1 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 AIM24164.1 - 4.3e-12 45.6 0.0 5.8e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 AIM24164.1 - 2.7e-09 36.5 0.0 4.7e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 AIM24164.1 - 5.4e-06 25.8 0.0 0.075 12.1 0.0 2.1 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 AIM24164.1 - 0.00058 19.1 0.0 0.051 12.7 0.0 2.7 2 1 0 2 2 2 1 Male sterility protein KR PF08659.10 AIM24164.1 - 0.0019 18.2 0.6 0.035 14.0 0.6 2.3 1 1 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 AIM24164.1 - 0.15 12.1 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 AIM24164.1 - 0.18 11.2 0.1 0.34 10.3 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Glyco_transf_9 PF01075.17 AIM24165.1 - 3.7e-85 285.2 0.0 4.3e-85 285.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 9 (heptosyltransferase) PS_pyruv_trans PF04230.13 AIM24165.1 - 0.00093 19.2 0.0 0.2 11.5 0.0 2.6 2 1 1 3 3 3 2 Polysaccharide pyruvyl transferase Glyco_transf_9 PF01075.17 AIM24166.1 - 7.5e-71 238.3 0.0 9.7e-71 238.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 9 (heptosyltransferase) Epimerase_2 PF02350.19 AIM24166.1 - 0.15 10.9 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase Glycos_transf_1 PF00534.20 AIM24167.1 - 6.8e-23 81.1 0.0 2e-22 79.6 0.0 1.9 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AIM24167.1 - 1.1e-14 55.0 0.0 2.4e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AIM24167.1 - 3e-10 40.4 0.1 4.5e-08 33.3 0.0 2.5 2 1 0 2 2 2 2 Glycosyltransferase Family 4 Wzy_C PF04932.15 AIM24168.1 - 7.1e-09 35.5 0.1 7.1e-09 35.5 0.1 2.9 2 1 0 2 2 2 1 O-Antigen ligase FixQ PF05545.11 AIM24168.1 - 0.31 11.0 7.5 1.6 8.7 0.7 3.8 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ Glycos_transf_2 PF00535.26 AIM24169.1 - 2.2e-27 96.0 0.0 4.6e-27 94.9 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 AIM24169.1 - 2.2e-12 47.0 0.1 5.1e-12 45.8 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 AIM24169.1 - 2.5e-11 43.9 0.0 3.8e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AIM24169.1 - 0.002 18.6 0.0 0.0095 16.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_9 PF01075.17 AIM24170.1 - 6.4e-22 78.1 0.0 1.1e-21 77.4 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 9 (heptosyltransferase) LysR_substrate PF03466.20 AIM24170.1 - 0.00081 18.8 0.1 1 8.7 0.0 2.7 3 0 0 3 3 3 2 LysR substrate binding domain Thioredoxin_9 PF14595.6 AIM24170.1 - 0.21 11.4 0.0 0.36 10.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Polysacc_deac_1 PF01522.21 AIM24171.1 - 0.1 12.5 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide deacetylase Glyco_transf_9 PF01075.17 AIM24172.1 - 3.7e-50 170.6 0.0 4.9e-50 170.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 9 (heptosyltransferase) Glycos_transf_1 PF00534.20 AIM24173.1 - 3.1e-28 98.5 0.0 5e-28 97.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AIM24173.1 - 1.8e-23 83.5 0.0 3.5e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AIM24173.1 - 1.9e-20 73.5 1.2 2.4e-20 73.2 0.3 1.7 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AIM24173.1 - 1.4e-09 38.6 0.9 4e-09 37.1 0.9 1.8 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 AIM24173.1 - 2.6e-05 24.5 0.0 6.7e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF2325 PF10087.9 AIM24173.1 - 0.027 14.6 0.0 0.1 12.8 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2325) DUF4930 PF16284.5 AIM24173.1 - 0.16 11.9 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4930) Glycos_transf_1 PF00534.20 AIM24174.1 - 4.6e-26 91.4 0.0 8.8e-26 90.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AIM24174.1 - 1.1e-21 77.7 0.0 1.8e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AIM24174.1 - 4.4e-17 62.6 0.2 7.2e-17 61.9 0.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AIM24174.1 - 3.8e-09 37.2 0.6 7.7e-09 36.2 0.6 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 AIM24174.1 - 0.0008 19.8 0.0 0.0033 17.8 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 AIM24174.1 - 0.026 14.6 0.0 0.057 13.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase 4-like Glyco_transf_9 PF01075.17 AIM24175.1 - 1.6e-23 83.3 0.0 2e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 9 (heptosyltransferase) Glycos_transf_N PF04413.16 AIM24176.1 - 5e-68 228.2 0.0 1.8e-67 226.5 0.0 1.8 2 0 0 2 2 2 1 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) Glycos_transf_1 PF00534.20 AIM24176.1 - 7.7e-08 32.1 0.0 4.6e-07 29.5 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AIM24176.1 - 0.023 15.1 0.0 0.044 14.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AIM24176.1 - 0.038 14.4 0.0 0.089 13.2 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 SNF2_N PF00176.23 AIM24176.1 - 0.18 10.5 0.0 0.23 10.1 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain Glycos_transf_2 PF00535.26 AIM24177.1 - 1.5e-19 70.5 0.1 2.1e-19 70.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_4 PF13704.6 AIM24177.1 - 2.7e-08 34.2 0.1 9.8e-08 32.4 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AIM24177.1 - 0.00042 20.3 0.0 0.00056 19.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 AIM24177.1 - 0.024 14.1 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Glyco_transf_49 PF13896.6 AIM24177.1 - 0.15 11.4 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl-transferase for dystroglycan CTP_transf_like PF01467.26 AIM24178.1 - 7e-20 71.7 0.0 8.2e-20 71.5 0.0 1.0 1 0 0 1 1 1 1 Cytidylyltransferase-like Citrate_ly_lig PF08218.11 AIM24178.1 - 5.9e-06 26.1 0.0 1.1e-05 25.2 0.0 1.4 1 1 0 1 1 1 1 Citrate lyase ligase C-terminal domain Fapy_DNA_glyco PF01149.24 AIM24179.1 - 1.8e-30 105.9 0.0 3.6e-30 105.0 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 AIM24179.1 - 8.4e-30 102.6 0.0 1.3e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain zf-FPG_IleRS PF06827.14 AIM24179.1 - 2.5e-11 43.2 7.4 4.4e-11 42.4 7.4 1.4 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS zf-dskA_traR PF01258.17 AIM24179.1 - 0.011 15.7 4.0 0.019 14.9 4.0 1.5 1 0 0 1 1 1 0 Prokaryotic dksA/traR C4-type zinc finger Auto_anti-p27 PF06677.12 AIM24179.1 - 0.17 12.1 1.0 0.33 11.2 1.0 1.5 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Ribosomal_L33 PF00471.20 AIM24180.1 - 1.3e-18 67.2 1.0 1.4e-18 67.0 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L33 Ribosomal_L28 PF00830.19 AIM24181.1 - 4.3e-26 90.9 1.2 4.9e-26 90.7 1.2 1.1 1 0 0 1 1 1 1 Ribosomal L28 family RadC PF04002.15 AIM24182.1 - 2.2e-44 150.3 0.1 3.4e-44 149.7 0.1 1.3 1 0 0 1 1 1 1 RadC-like JAB domain Prok-JAB PF14464.6 AIM24182.1 - 0.00021 21.0 0.1 0.00034 20.4 0.1 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain RNB PF00773.19 AIM24182.1 - 0.05 12.9 0.0 0.063 12.6 0.0 1.1 1 0 0 1 1 1 0 RNB domain HHH_2 PF12826.7 AIM24182.1 - 0.08 13.0 0.0 0.32 11.1 0.0 1.9 1 1 0 1 1 1 0 Helix-hairpin-helix motif PA PF02225.22 AIM24182.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 PA domain DFP PF04127.15 AIM24183.1 - 4.7e-77 258.0 4.2 7.4e-76 254.1 0.7 2.2 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Flavoprotein PF02441.19 AIM24183.1 - 1.9e-43 148.0 0.1 4.9e-43 146.6 0.0 1.8 2 1 0 2 2 2 1 Flavoprotein YjeF_N PF03853.15 AIM24183.1 - 0.012 15.5 0.1 0.12 12.2 0.0 2.3 2 0 0 2 2 2 0 YjeF-related protein N-terminus Glyco_transf_4 PF13439.6 AIM24183.1 - 0.19 11.7 1.0 21 5.1 0.1 2.7 2 2 0 2 2 2 0 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AIM24183.1 - 0.35 11.3 12.1 2.9 8.3 4.6 2.9 2 2 0 2 2 2 0 Glycosyl transferase 4-like domain dUTPase PF00692.19 AIM24184.1 - 2.9e-44 149.8 0.0 3.3e-44 149.7 0.0 1.0 1 0 0 1 1 1 1 dUTPase TetR_N PF00440.23 AIM24185.1 - 1.4e-08 34.4 0.0 2.2e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_15 PF17918.1 AIM24185.1 - 0.016 15.9 0.8 0.55 11.0 0.1 2.5 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain HTH_AsnC-type PF13404.6 AIM24185.1 - 0.044 13.6 0.2 0.11 12.4 0.2 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain DUF390 PF04094.14 AIM24185.1 - 0.16 10.2 0.3 0.14 10.4 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF390) Pribosyltran PF00156.27 AIM24186.1 - 1.2e-11 44.4 0.0 1.9e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain TAF4 PF05236.14 AIM24186.1 - 0.039 13.7 0.0 0.04 13.7 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family RNase_PH PF01138.21 AIM24187.1 - 5.4e-24 85.2 0.0 9.2e-24 84.4 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 AIM24187.1 - 5e-11 42.5 0.4 8.2e-11 41.8 0.4 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 BrnA_antitoxin PF14384.6 AIM24187.1 - 0.17 12.4 0.1 2.7 8.6 0.0 2.2 2 0 0 2 2 2 0 BrnA antitoxin of type II toxin-antitoxin system YicC_N PF03755.13 AIM24188.1 - 7.1e-44 149.9 0.1 7.1e-44 149.9 0.1 2.2 2 1 0 2 2 2 1 YicC-like family, N-terminal region DUF1732 PF08340.11 AIM24188.1 - 1.4e-34 117.9 6.8 4e-34 116.5 6.8 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1732) Baculo_PEP_C PF04513.12 AIM24188.1 - 0.029 14.4 4.9 0.38 10.8 0.1 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cnn_1N PF07989.11 AIM24188.1 - 2 8.6 12.9 1.4 9.2 0.5 3.0 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 Nucleos_tra2_C PF07662.13 AIM24190.1 - 3.6e-62 209.9 14.6 3.6e-62 209.9 14.6 2.4 2 1 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 AIM24190.1 - 2.5e-18 66.4 4.1 2.5e-18 66.4 4.1 4.2 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 AIM24190.1 - 4.1e-05 23.8 8.1 4.1e-05 23.8 8.1 3.8 2 1 2 4 4 4 1 Nucleoside recognition DUF3574 PF12098.8 AIM24191.1 - 4.7e-39 132.3 0.0 5.7e-39 132.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3574) GPP34 PF05719.11 AIM24191.1 - 0.01 15.9 0.0 0.012 15.7 0.0 1.2 1 0 0 1 1 1 0 Golgi phosphoprotein 3 (GPP34) UPF0126 PF03458.13 AIM24192.1 - 5.1e-43 144.8 21.1 6.6e-22 77.2 6.2 2.3 2 0 0 2 2 2 2 UPF0126 domain ICMT PF04140.14 AIM24192.1 - 0.31 11.5 3.7 0.21 12.0 0.8 2.2 1 1 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Guanylate_kin PF00625.21 AIM24193.1 - 3.2e-69 232.3 0.0 3.7e-69 232.1 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.6 AIM24193.1 - 9e-05 22.7 0.1 0.00072 19.7 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AIM24193.1 - 0.0003 21.3 0.0 0.00055 20.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AIM24193.1 - 0.00035 21.0 0.5 0.0014 19.1 0.5 1.8 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AIM24193.1 - 0.0023 17.9 0.2 0.0048 16.8 0.1 1.6 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 AIM24193.1 - 0.0027 18.0 0.3 0.024 14.9 0.3 2.2 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 AIM24193.1 - 0.005 17.4 0.0 0.0064 17.0 0.0 1.4 1 1 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.23 AIM24193.1 - 0.032 14.3 0.0 0.064 13.3 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.6 AIM24193.1 - 0.1 12.2 0.5 6.4 6.3 0.1 2.2 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 AIM24193.1 - 0.11 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 AIM24193.1 - 0.2 11.6 0.0 0.36 10.7 0.0 1.5 1 1 0 1 1 1 0 Rad17 P-loop domain RNA_pol_Rpb6 PF01192.22 AIM24194.1 - 5.8e-17 61.4 0.2 9.5e-17 60.7 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 HD_4 PF13328.6 AIM24195.1 - 1e-54 184.5 1.3 2e-54 183.6 1.3 1.5 1 0 0 1 1 1 1 HD domain RelA_SpoT PF04607.17 AIM24195.1 - 1.2e-36 125.5 1.1 2.5e-36 124.5 0.2 2.0 2 0 0 2 2 2 1 Region found in RelA / SpoT proteins TGS PF02824.21 AIM24195.1 - 5.8e-21 74.3 0.0 1.4e-20 73.1 0.0 1.7 1 0 0 1 1 1 1 TGS domain ACT_4 PF13291.6 AIM24195.1 - 2.1e-15 57.1 2.9 2.6e-15 56.8 1.3 2.2 2 0 0 2 2 2 1 ACT domain HD PF01966.22 AIM24195.1 - 6.6e-12 45.7 0.6 6.6e-12 45.7 0.6 2.1 2 0 0 2 2 2 1 HD domain TFIIS_M PF07500.14 AIM24195.1 - 0.048 14.1 1.3 0.11 13.0 0.1 2.2 2 1 0 2 2 2 0 Transcription factor S-II (TFIIS), central domain EMC3_TMCO1 PF01956.16 AIM24195.1 - 0.073 12.8 0.5 0.17 11.6 0.5 1.5 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like SpoU_methylase PF00588.19 AIM24196.1 - 3e-35 121.4 0.1 3.9e-35 121.1 0.1 1.1 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_methylas_C PF12105.8 AIM24196.1 - 4.1e-24 84.0 0.6 7.7e-24 83.1 0.6 1.5 1 0 0 1 1 1 1 SpoU, rRNA methylase, C-terminal RecG_wedge PF17191.4 AIM24197.1 - 9.3e-22 77.4 0.0 1.6e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 RecG wedge domain Helicase_C PF00271.31 AIM24197.1 - 4.8e-20 72.0 0.0 1.8e-18 66.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 AIM24197.1 - 1.8e-19 70.2 2.3 3.9e-19 69.1 0.1 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.15 AIM24197.1 - 2e-12 47.5 0.0 3.2e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit tRNA_anti-codon PF01336.25 AIM24197.1 - 9.4e-09 35.1 0.0 3.9e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain SecA_DEAD PF07517.14 AIM24197.1 - 1.6e-06 27.6 0.5 4.1e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 SecA DEAD-like domain AAA_30 PF13604.6 AIM24197.1 - 7.3e-06 25.8 1.7 0.00012 21.9 1.7 2.5 1 1 0 1 1 1 1 AAA domain SNF2_N PF00176.23 AIM24197.1 - 0.0041 15.9 0.0 0.0059 15.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_RecD PF05127.14 AIM24197.1 - 0.013 15.4 0.1 0.032 14.1 0.1 1.7 1 0 0 1 1 1 0 Helicase ERCC3_RAD25_C PF16203.5 AIM24197.1 - 0.017 14.4 0.0 0.048 12.9 0.0 1.6 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase DUF2075 PF09848.9 AIM24197.1 - 0.017 14.3 0.1 0.027 13.7 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Glyco_tran_WecB PF03808.13 AIM24197.1 - 0.041 13.8 1.1 3.4 7.6 0.1 3.3 3 1 1 4 4 4 0 Glycosyl transferase WecB/TagA/CpsF family DNA_pol_lambd_f PF10391.9 AIM24197.1 - 0.061 13.2 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda RC-P840_PscD PF10657.9 AIM24197.1 - 0.09 12.9 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Photosystem P840 reaction centre protein PscD Cdd1 PF11731.8 AIM24197.1 - 0.11 12.7 0.0 0.47 10.7 0.0 2.0 2 0 0 2 2 2 0 Pathogenicity locus AAA_22 PF13401.6 AIM24197.1 - 0.33 11.2 1.3 4.8 7.5 0.2 3.0 2 2 0 2 2 2 0 AAA domain Sugarporin_N PF11471.8 AIM24198.1 - 0.015 15.3 0.4 0.023 14.6 0.4 1.2 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension TRAF_BIRC3_bd PF16673.5 AIM24198.1 - 0.036 13.8 0.1 0.062 13.1 0.1 1.4 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain PKcGMP_CC PF16808.5 AIM24198.1 - 0.053 13.4 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Pox_A_type_inc PF04508.12 AIM24198.1 - 0.18 11.7 0.4 0.41 10.6 0.4 1.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat rve PF00665.26 AIM24199.1 - 1.2e-26 93.2 0.1 2.1e-26 92.5 0.1 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 AIM24199.1 - 2.8e-20 71.9 0.0 5.8e-20 70.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 AIM24199.1 - 0.00086 19.6 0.0 0.0017 18.6 0.0 1.5 1 0 0 1 1 1 1 DDE domain HTH_21 PF13276.6 AIM24199.1 - 0.0028 17.8 1.6 0.0061 16.7 0.7 2.0 2 0 0 2 2 2 1 HTH-like domain rve_2 PF13333.6 AIM24199.1 - 0.0055 16.9 0.0 0.01 16.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DUF4802 PF16060.5 AIM24199.1 - 0.079 13.1 0.9 0.16 12.2 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4802) Glt_symporter PF03616.14 AIM24200.1 - 9.3e-160 531.3 21.4 1.2e-159 530.9 21.4 1.1 1 0 0 1 1 1 1 Sodium/glutamate symporter SVM_signal PF12113.8 AIM24200.1 - 0.043 13.7 1.5 0.14 12.0 1.5 1.9 1 0 0 1 1 1 0 SVM protein signal sequence YlaH PF14036.6 AIM24200.1 - 1.5 9.2 20.3 0.059 13.7 7.3 3.5 3 1 1 4 4 4 0 YlaH-like protein Xan_ur_permease PF00860.20 AIM24201.1 - 9.7e-108 360.3 37.2 1.3e-107 359.9 37.2 1.2 1 0 0 1 1 1 1 Permease family SprB PF13573.6 AIM24201.1 - 0.039 13.7 0.3 0.075 12.8 0.3 1.5 1 0 0 1 1 1 0 SprB repeat YtpI PF14007.6 AIM24201.1 - 0.71 10.1 6.2 1 9.5 0.6 3.1 2 0 0 2 2 2 0 YtpI-like protein DUF3925 PF13063.6 AIM24201.1 - 3.9 7.8 8.7 0.23 11.7 0.8 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3925) AsmA PF05170.14 AIM24202.1 - 1e-22 80.7 14.7 7.6e-15 54.7 2.8 3.9 3 1 0 3 3 3 3 AsmA family AsmA_2 PF13502.6 AIM24202.1 - 1.2e-07 31.5 12.7 3.6e-07 29.9 0.8 4.1 3 1 0 3 3 3 2 AsmA-like C-terminal region DUF4097 PF13349.6 AIM24202.1 - 0.00045 19.6 0.1 0.24 10.7 0.0 2.6 3 0 0 3 3 3 2 Putative adhesin YiiD_C PF09500.10 AIM24203.1 - 4.3e-46 156.3 0.0 6.2e-46 155.8 0.0 1.2 1 0 0 1 1 1 1 Putative thioesterase (yiiD_Cterm) Acetyltransf_1 PF00583.25 AIM24203.1 - 6.7e-14 52.1 0.0 1.1e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AIM24203.1 - 4e-11 42.9 0.0 6.6e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AIM24203.1 - 2e-06 28.2 0.0 3.7e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.6 AIM24203.1 - 0.00049 20.8 0.0 0.00099 19.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AIM24203.1 - 0.00099 19.0 0.0 0.0022 17.9 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein DUF4442 PF14539.6 AIM24203.1 - 0.0011 19.2 0.0 0.0018 18.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) Acetyltransf_4 PF13420.7 AIM24203.1 - 0.016 15.4 0.0 0.026 14.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Peptidase_S32 PF05579.13 AIM24203.1 - 0.054 12.7 0.0 0.087 12.0 0.0 1.2 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 Tyr_Deacylase PF02580.16 AIM24204.1 - 2e-52 177.6 0.1 2.4e-52 177.3 0.1 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Virul_fac_BrkB PF03631.15 AIM24205.1 - 9.7e-59 199.1 22.7 1.1e-58 198.9 22.7 1.0 1 0 0 1 1 1 1 Virulence factor BrkB SpoIIIAC PF06686.11 AIM24205.1 - 4.8 7.4 7.7 12 6.2 0.2 3.2 3 0 0 3 3 3 0 Stage III sporulation protein AC/AD protein family HAD_2 PF13419.6 AIM24206.1 - 7.9e-09 35.8 0.5 1e-08 35.5 0.0 1.5 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AIM24206.1 - 8.6e-05 22.9 0.0 0.00044 20.6 0.0 1.8 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AIM24206.1 - 0.0035 17.8 0.1 0.0052 17.2 0.1 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 AIM24206.1 - 0.0044 16.9 0.0 0.17 11.7 0.0 2.2 2 0 0 2 2 2 1 Acid Phosphatase SHOCT PF09851.9 AIM24206.1 - 0.031 14.0 0.0 0.21 11.4 0.1 2.1 2 0 0 2 2 2 0 Short C-terminal domain NT5C PF06941.12 AIM24206.1 - 0.073 12.9 0.1 0.12 12.2 0.1 1.5 1 1 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Hydrolase_6 PF13344.6 AIM24206.1 - 0.076 13.1 0.0 0.8 9.9 0.0 2.4 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AIM24206.1 - 0.077 13.1 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like Urocanase PF01175.18 AIM24206.1 - 0.088 12.4 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Urocanase Rossmann-like domain PNK3P PF08645.11 AIM24206.1 - 0.12 12.0 0.0 0.45 10.2 0.0 1.9 1 1 0 1 1 1 0 Polynucleotide kinase 3 phosphatase GTP_EFTU PF00009.27 AIM24207.1 - 1.9e-57 194.0 0.1 3.3e-57 193.2 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 AIM24207.1 - 5e-21 74.5 0.0 1.2e-20 73.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 AIM24207.1 - 6.7e-10 39.2 3.4 1.9e-09 37.8 3.4 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 AIM24207.1 - 3.3e-07 30.4 0.4 1.6e-06 28.1 0.1 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase EFG_II PF14492.6 AIM24207.1 - 0.00012 22.1 2.1 0.0002 21.4 0.0 2.4 4 0 0 4 4 3 1 Elongation Factor G, domain II Septin PF00735.18 AIM24207.1 - 0.0016 17.8 0.1 0.0028 17.0 0.1 1.3 1 0 0 1 1 1 1 Septin FeoB_N PF02421.18 AIM24207.1 - 0.02 14.5 0.1 0.39 10.2 0.0 3.1 2 1 0 2 2 2 0 Ferrous iron transport protein B Dynamin_N PF00350.23 AIM24207.1 - 0.036 14.1 0.1 0.67 10.0 0.0 2.6 2 1 0 2 2 2 0 Dynamin family SRPRB PF09439.10 AIM24207.1 - 0.051 13.0 0.0 0.14 11.6 0.0 1.7 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AIG1 PF04548.16 AIM24207.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 AIG1 family DUF4190 PF13828.6 AIM24207.1 - 0.12 12.1 1.7 0.22 11.3 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) Gln-synt_C PF00120.24 AIM24208.1 - 2.1e-136 454.5 0.0 2.5e-136 454.2 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 AIM24208.1 - 2.7e-32 110.3 0.1 6.2e-32 109.2 0.1 1.6 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain HATPase_c PF02518.26 AIM24209.1 - 1.6e-15 57.6 0.0 4.7e-15 56.1 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AIM24209.1 - 5.2e-14 52.0 1.1 1.2e-13 50.9 0.1 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 AIM24209.1 - 5e-07 29.7 0.0 1.5e-06 28.1 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AIM24209.1 - 0.00053 20.2 0.0 0.0014 18.8 0.0 1.8 1 1 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AIM24209.1 - 0.00083 19.6 0.0 0.0017 18.6 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 AIM24209.1 - 0.0011 19.0 0.0 0.0045 17.0 0.0 2.1 1 0 0 1 1 1 1 PAS domain DUF1688 PF07958.11 AIM24209.1 - 0.021 13.6 0.1 0.033 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1688) Sigma54_activat PF00158.26 AIM24210.1 - 5.6e-70 234.4 0.0 8.4e-70 233.8 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Response_reg PF00072.24 AIM24210.1 - 4.7e-31 107.2 0.0 8.8e-31 106.4 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Sigma54_activ_2 PF14532.6 AIM24210.1 - 3.8e-23 82.1 0.0 2.9e-22 79.3 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 AIM24210.1 - 2.2e-16 59.3 1.8 2e-15 56.3 1.5 2.3 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 AIM24210.1 - 1.5e-07 31.5 0.0 3.2e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 AIM24210.1 - 2.5e-05 24.5 0.0 4.3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 AIM24210.1 - 0.00082 19.8 0.0 0.0026 18.2 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 AIM24210.1 - 0.0066 15.9 0.1 0.76 9.1 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 AIM24210.1 - 0.028 13.9 0.0 0.15 11.5 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region FleQ PF06490.11 AIM24210.1 - 0.033 14.5 0.0 0.094 13.1 0.0 1.8 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ MCM PF00493.23 AIM24210.1 - 0.12 11.4 0.0 0.32 10.1 0.0 1.6 1 1 0 1 1 1 0 MCM P-loop domain AAA_16 PF13191.6 AIM24210.1 - 0.13 12.7 0.6 0.46 10.8 0.6 2.2 1 1 0 1 1 1 0 AAA ATPase domain DUF3948 PF13134.6 AIM24211.1 - 0.52 10.1 2.8 2.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3948) Radical_SAM PF04055.21 AIM24212.1 - 5.6e-17 62.6 0.0 8.7e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily HemN_C PF06969.16 AIM24212.1 - 4.8e-12 45.7 0.6 2e-11 43.8 0.3 2.3 2 0 0 2 2 2 1 HemN C-terminal domain YihI PF04220.12 AIM24213.1 - 1.1e-52 178.0 13.3 1.2e-52 177.8 13.3 1.0 1 0 0 1 1 1 1 Der GTPase activator (YihI) MMR_HSR1 PF01926.23 AIM24215.1 - 3.6e-21 75.4 0.0 5.2e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AIM24215.1 - 4.5e-07 29.5 0.0 6.2e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 AIM24215.1 - 2.7e-06 27.4 0.0 0.00099 19.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 AIM24215.1 - 1.9e-05 24.8 0.0 0.14 12.2 0.1 2.2 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 AIM24215.1 - 0.0011 18.5 0.2 0.019 14.5 0.1 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 AIM24215.1 - 0.0069 16.1 0.0 0.043 13.6 0.0 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 AIM24215.1 - 0.01 15.3 0.0 0.02 14.3 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 AIM24215.1 - 0.081 13.2 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AIG1 PF04548.16 AIM24215.1 - 0.1 11.9 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 AIG1 family DNA_pol_A PF00476.20 AIM24216.1 - 3.4e-154 513.4 0.0 4.8e-154 513.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A 5_3_exonuc_N PF02739.16 AIM24216.1 - 1.1e-54 184.6 0.0 1.9e-54 183.8 0.0 1.4 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain DNA_pol_A_exo1 PF01612.20 AIM24216.1 - 1.1e-45 155.5 0.2 2e-45 154.7 0.2 1.4 1 0 0 1 1 1 1 3'-5' exonuclease 5_3_exonuc PF01367.20 AIM24216.1 - 1.1e-30 106.1 0.3 3.4e-30 104.5 0.0 2.0 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH PF00633.23 AIM24216.1 - 0.0073 16.1 0.1 0.038 13.9 0.1 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif SCP2 PF02036.17 AIM24216.1 - 0.02 15.3 0.3 1.2 9.6 0.0 2.7 2 0 0 2 2 2 0 SCP-2 sterol transfer family HHH_5 PF14520.6 AIM24216.1 - 0.042 14.4 0.0 0.17 12.5 0.0 2.1 1 0 0 1 1 1 0 Helix-hairpin-helix domain Ribosomal_60s PF00428.19 AIM24216.1 - 0.19 12.4 3.7 0.5 11.0 2.2 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein Sigma54_AID PF00309.20 AIM24216.1 - 5.6 6.9 6.3 3.2 7.7 0.5 2.9 3 0 0 3 3 3 0 Sigma-54 factor, Activator interacting domain (AID) Acyltransferase PF01553.21 AIM24217.1 - 2.3e-12 46.7 0.0 3.2e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 AIM24217.1 - 0.0046 17.0 1.9 0.015 15.4 0.6 2.4 2 1 0 2 2 2 1 Acyltransferase C-terminus DSBA PF01323.20 AIM24218.1 - 7.8e-30 104.1 4.6 7.6e-29 100.9 4.6 1.9 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 AIM24218.1 - 1.2e-11 45.1 0.1 1.5e-11 44.7 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin PF00085.20 AIM24218.1 - 0.0016 18.4 0.1 0.12 12.3 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 AIM24218.1 - 0.026 15.0 0.9 0.73 10.3 0.9 2.2 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_3 PF13192.6 AIM24218.1 - 0.037 14.1 0.1 3 8.0 0.0 2.5 2 1 0 2 2 2 0 Thioredoxin domain Glutaredoxin PF00462.24 AIM24218.1 - 0.044 14.0 0.8 0.87 9.8 0.0 2.4 2 0 0 2 2 2 0 Glutaredoxin Thioredoxin_14 PF18402.1 AIM24218.1 - 0.06 13.3 0.1 0.06 13.3 0.1 1.3 1 1 0 1 1 1 0 Thioredoxin-like domain APH PF01636.23 AIM24219.1 - 3.3e-45 154.9 9.1 3.3e-45 154.9 9.1 1.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 AIM24219.1 - 0.28 9.9 0.0 0.65 8.7 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase DUF1040 PF06288.13 AIM24220.1 - 7.4e-45 151.2 0.1 8.3e-45 151.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1040) NTP_transf_3 PF12804.7 AIM24221.1 - 9.5e-35 120.3 2.3 1.2e-34 120.0 2.3 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain MobB PF03205.14 AIM24222.1 - 3.2e-47 159.8 0.0 3.8e-47 159.5 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.19 AIM24222.1 - 0.00067 19.3 0.0 0.0012 18.5 0.0 1.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.23 AIM24222.1 - 0.0075 16.3 0.0 0.01 15.9 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 AIM24222.1 - 0.011 16.1 0.1 0.014 15.8 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.15 AIM24222.1 - 0.025 14.5 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 NTPase NACHT PF05729.12 AIM24222.1 - 0.069 13.1 0.1 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 AIM24222.1 - 0.074 13.6 0.0 0.074 13.6 0.0 1.2 1 0 0 1 1 1 0 ABC transporter PRK PF00485.18 AIM24222.1 - 0.082 12.6 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.6 AIM24222.1 - 0.1 12.9 0.1 0.16 12.3 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AIM24222.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_26 PF13500.6 AIM24222.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain LpxK PF02606.14 AIM24222.1 - 0.13 11.4 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase AAA_19 PF13245.6 AIM24222.1 - 0.14 12.5 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain FCD PF07729.12 AIM24223.1 - 7.2e-25 87.8 0.9 1.2e-24 87.1 0.9 1.4 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 AIM24223.1 - 9.3e-19 66.9 0.2 1.9e-18 65.9 0.2 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family FadR_C PF07840.12 AIM24223.1 - 0.0024 17.8 0.0 0.0034 17.3 0.0 1.2 1 0 0 1 1 1 1 FadR C-terminal domain HTH_11 PF08279.12 AIM24223.1 - 0.0034 17.3 0.0 0.01 15.8 0.0 1.7 1 0 0 1 1 1 1 HTH domain PaaX PF07848.12 AIM24223.1 - 0.031 14.5 0.2 0.081 13.2 0.0 1.8 2 0 0 2 2 2 0 PaaX-like protein Peptidase_C50 PF03568.17 AIM24223.1 - 0.056 12.6 0.4 0.072 12.2 0.4 1.1 1 0 0 1 1 1 0 Peptidase family C50 HTH_24 PF13412.6 AIM24223.1 - 0.077 12.6 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 AIM24223.1 - 0.14 12.0 0.1 0.44 10.4 0.0 1.9 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain MFS_1 PF07690.16 AIM24224.1 - 2.1e-49 168.4 81.0 3e-42 144.8 54.7 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 AIM24224.1 - 7.6e-06 24.6 9.0 1.1e-05 24.1 8.7 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 AIM24224.1 - 1.3e-05 24.7 12.1 1.3e-05 24.7 12.1 2.7 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 AIM24224.1 - 0.00018 20.0 24.6 0.00038 19.0 9.4 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector Gram_pos_anchor PF00746.21 AIM24224.1 - 4.5 7.3 0.0 4.5 7.3 0.0 4.3 4 0 0 4 4 4 0 LPXTG cell wall anchor motif Peripla_BP_3 PF13377.6 AIM24225.1 - 1.8e-44 152.0 0.4 5.1e-44 150.5 0.2 1.8 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 AIM24225.1 - 1.7e-33 116.3 0.0 2.1e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 AIM24225.1 - 3.9e-21 74.6 1.7 7e-21 73.7 1.7 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 AIM24225.1 - 8e-18 64.9 0.0 1.2e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein domain HTH_38 PF13936.6 AIM24225.1 - 0.0022 17.7 0.3 0.11 12.3 0.0 3.6 5 0 0 5 5 5 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 AIM24225.1 - 0.0052 16.2 0.3 0.011 15.2 0.3 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_31 PF13560.6 AIM24225.1 - 0.017 15.5 0.0 0.045 14.1 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_3 PF01381.22 AIM24225.1 - 0.019 15.0 0.0 0.066 13.3 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix MerR PF00376.23 AIM24225.1 - 0.1 12.4 0.1 0.25 11.1 0.1 1.7 1 0 0 1 1 1 0 MerR family regulatory protein HTH_23 PF13384.6 AIM24225.1 - 0.12 12.2 0.0 0.41 10.5 0.0 1.9 1 0 0 1 1 1 0 Homeodomain-like domain HTH_IclR PF09339.10 AIM24225.1 - 0.17 11.7 1.1 5.4 6.9 0.0 3.2 3 0 0 3 3 3 0 IclR helix-turn-helix domain Rad10 PF03834.14 AIM24225.1 - 0.19 11.8 0.0 0.37 10.8 0.0 1.4 1 0 0 1 1 1 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) PfkB PF00294.24 AIM24226.1 - 8.5e-75 251.8 3.6 9.6e-75 251.7 3.6 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 AIM24226.1 - 7.3e-13 48.5 0.4 1.1e-12 47.9 0.4 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Carb_kinase PF01256.17 AIM24226.1 - 0.00018 21.1 0.8 0.007 15.9 0.2 2.3 2 0 0 2 2 2 2 Carbohydrate kinase Peripla_BP_4 PF13407.6 AIM24227.1 - 5.8e-59 199.7 10.5 6.9e-59 199.5 10.5 1.0 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 AIM24227.1 - 2.5e-25 89.5 1.5 3e-25 89.2 1.5 1.0 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_6 PF13458.6 AIM24227.1 - 8.5e-15 55.3 4.7 1.8e-14 54.2 4.6 1.4 1 1 1 2 2 2 1 Periplasmic binding protein Peripla_BP_3 PF13377.6 AIM24227.1 - 9.3e-14 52.1 0.1 2.3e-12 47.6 0.1 2.1 2 0 0 2 2 2 1 Periplasmic binding protein-like domain ABC_sub_bind PF04392.12 AIM24227.1 - 0.00023 20.5 6.8 0.017 14.4 0.7 2.3 1 1 1 2 2 2 2 ABC transporter substrate binding protein ATPgrasp_N PF18130.1 AIM24227.1 - 0.017 15.7 0.2 0.55 10.8 0.0 2.7 2 0 0 2 2 2 0 ATP-grasp N-terminal domain BPD_transp_2 PF02653.16 AIM24228.1 - 1.6e-52 178.4 41.8 1.6e-52 178.4 41.8 1.3 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component ABC_tran PF00005.27 AIM24229.1 - 1.4e-54 184.4 0.0 1.1e-27 97.2 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 AIM24229.1 - 3.2e-08 33.7 0.2 0.033 14.0 0.0 3.1 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AIM24229.1 - 0.00014 21.4 0.0 0.087 12.2 0.7 2.9 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 AIM24229.1 - 0.00065 19.6 0.2 0.064 13.2 0.1 2.7 3 0 0 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 AIM24229.1 - 0.0022 18.3 1.1 0.29 11.4 0.2 3.2 2 2 0 2 2 2 1 AAA domain AAA_30 PF13604.6 AIM24229.1 - 0.0037 17.0 6.3 0.0047 16.7 0.2 2.9 3 1 0 3 3 3 1 AAA domain AAA_29 PF13555.6 AIM24229.1 - 0.0067 16.2 0.1 0.017 14.8 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_ATPase PF09818.9 AIM24229.1 - 0.0074 15.1 3.0 0.42 9.4 0.0 2.8 3 1 0 3 3 3 2 Predicted ATPase of the ABC class Ploopntkinase3 PF18751.1 AIM24229.1 - 0.013 15.4 0.2 0.03 14.2 0.0 1.6 2 0 0 2 2 1 0 P-loop Nucleotide Kinase3 TsaE PF02367.17 AIM24229.1 - 0.017 15.1 0.8 1.3 9.0 0.1 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_15 PF13175.6 AIM24229.1 - 0.021 14.6 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 AIM24229.1 - 0.029 14.4 0.1 0.29 11.2 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 AIM24229.1 - 0.042 13.6 0.7 10 5.8 0.1 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 AIM24229.1 - 0.053 14.0 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2813 PF11398.8 AIM24229.1 - 0.093 12.0 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) AAA_16 PF13191.6 AIM24229.1 - 0.097 13.0 0.0 1.7 9.0 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain MEDS PF14417.6 AIM24229.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain AAA PF00004.29 AIM24229.1 - 0.21 12.0 3.3 22 5.5 0.8 4.1 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 AIM24229.1 - 0.4 9.9 1.4 10 5.3 0.2 2.3 2 0 0 2 2 2 0 Zeta toxin RbsD_FucU PF05025.13 AIM24230.1 - 7.4e-47 159.1 0.1 8.2e-47 159.0 0.1 1.0 1 0 0 1 1 1 1 RbsD / FucU transport protein family DUF1931 PF09123.11 AIM24230.1 - 0.095 12.8 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1931) K_trans PF02705.16 AIM24231.1 - 7.9e-207 688.0 23.7 9.1e-207 687.8 23.7 1.0 1 0 0 1 1 1 1 K+ potassium transporter YIF1 PF03878.15 AIM24231.1 - 0.29 10.6 5.1 0.87 9.1 0.6 2.5 2 0 0 2 2 2 0 YIF1 AAA_5 PF07728.14 AIM24232.1 - 1.3e-25 90.0 0.0 2.2e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_8 PF17868.1 AIM24232.1 - 1.9e-22 79.0 0.3 5.5e-22 77.4 0.1 1.9 1 1 1 2 2 2 1 AAA lid domain DUF3763 PF12592.8 AIM24232.1 - 3.9e-18 65.2 4.5 3.9e-18 65.2 4.5 3.2 4 0 0 4 4 4 1 Protein of unknown function (DUF3763) Mg_chelatase PF01078.21 AIM24232.1 - 0.00049 19.5 0.0 0.003 17.0 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA PF00004.29 AIM24232.1 - 0.00049 20.5 0.0 0.015 15.8 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.11 AIM24232.1 - 0.00062 19.6 0.0 0.0017 18.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 AIM24232.1 - 0.0009 19.0 0.0 0.016 14.9 0.0 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 AIM24232.1 - 0.016 15.6 5.6 0.28 11.6 5.6 3.0 1 1 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.17 AIM24232.1 - 0.037 13.8 0.0 0.55 9.9 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_2 PF07724.14 AIM24232.1 - 0.11 12.6 0.0 0.32 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) VWA_CoxE PF05762.14 AIM24233.1 - 2.7e-06 26.9 0.0 4.4e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein VWA_2 PF13519.6 AIM24233.1 - 5.7e-06 26.9 0.0 1.3e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF2201 PF09967.9 AIM24233.1 - 0.057 13.6 0.0 0.094 12.9 0.0 1.4 1 0 0 1 1 1 0 VWA-like domain (DUF2201) AsnA PF03590.15 AIM24234.1 - 3.6e-94 314.8 0.0 4.4e-94 314.5 0.0 1.1 1 0 0 1 1 1 1 Aspartate-ammonia ligase tRNA-synt_2 PF00152.20 AIM24234.1 - 7.6e-05 21.9 0.1 0.0017 17.5 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) AsnC_trans_reg PF01037.21 AIM24235.1 - 2.5e-17 62.6 0.1 4.4e-17 61.8 0.1 1.4 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 AIM24235.1 - 1.1e-13 50.4 0.0 2.2e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 AIM24235.1 - 5.3e-13 48.6 0.0 9.9e-13 47.7 0.0 1.5 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_20 PF12840.7 AIM24235.1 - 0.00016 21.7 0.0 0.00034 20.6 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_11 PF08279.12 AIM24235.1 - 0.00021 21.2 0.0 0.00059 19.7 0.0 1.8 1 0 0 1 1 1 1 HTH domain MarR_2 PF12802.7 AIM24235.1 - 0.0011 18.8 0.0 0.002 18.0 0.0 1.3 1 0 0 1 1 1 1 MarR family B-block_TFIIIC PF04182.12 AIM24235.1 - 0.018 15.2 0.1 0.17 12.1 0.0 2.3 2 1 1 3 3 3 0 B-block binding subunit of TFIIIC HTH_41 PF14502.6 AIM24235.1 - 0.021 14.5 0.5 0.33 10.7 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_5 PF01022.20 AIM24235.1 - 0.042 13.7 0.0 0.088 12.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_28 PF13518.6 AIM24235.1 - 0.14 12.3 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Flavodoxin_1 PF00258.25 AIM24236.1 - 5.3e-27 94.8 0.0 6e-27 94.6 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin FMN_red PF03358.15 AIM24236.1 - 0.00098 18.9 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_5 PF12724.7 AIM24236.1 - 0.032 14.5 0.0 0.066 13.4 0.0 1.5 1 1 0 1 1 1 0 Flavodoxin domain XPC-binding PF09280.11 AIM24236.1 - 0.033 13.9 2.0 0.055 13.2 2.0 1.3 1 0 0 1 1 1 0 XPC-binding domain GIDA PF01134.22 AIM24237.1 - 2e-168 560.5 0.0 2.6e-168 560.2 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 AIM24237.1 - 2.1e-76 256.8 1.2 3.1e-76 256.2 1.2 1.2 1 0 0 1 1 1 1 GidA associated domain FAD_binding_2 PF00890.24 AIM24237.1 - 3.2e-08 33.1 1.8 0.00019 20.7 0.2 2.3 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 AIM24237.1 - 7e-08 32.2 1.9 1.2e-07 31.5 1.9 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 AIM24237.1 - 2.3e-05 23.8 0.3 4.8e-05 22.7 0.3 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AIM24237.1 - 4.8e-05 22.2 2.0 0.0021 16.9 0.2 2.8 3 0 0 3 3 3 1 HI0933-like protein DAO PF01266.24 AIM24237.1 - 0.00014 21.6 0.3 0.35 10.4 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 AIM24237.1 - 0.00022 20.6 0.7 0.00047 19.5 0.7 1.6 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 AIM24237.1 - 0.011 14.9 0.8 0.12 11.6 0.8 2.1 1 1 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 AIM24237.1 - 0.017 15.7 0.2 0.05 14.2 0.2 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AIM24237.1 - 0.18 11.0 0.1 0.43 9.8 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 AIM24237.1 - 0.28 11.1 2.5 0.3 11.0 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 AIM24237.1 - 0.45 10.8 3.1 0.5 10.6 0.5 2.5 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain GidB PF02527.15 AIM24238.1 - 1.2e-58 197.5 0.0 1.4e-58 197.3 0.0 1.0 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_31 PF13847.6 AIM24238.1 - 1.8e-06 27.8 0.0 2.2e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AIM24238.1 - 9e-05 23.1 0.0 0.00013 22.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AIM24238.1 - 0.021 14.4 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain RecA PF00154.21 AIM24239.1 - 3.3e-131 436.5 1.7 4e-131 436.3 1.7 1.0 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Rad51 PF08423.11 AIM24239.1 - 8.6e-14 51.4 0.3 2.8e-13 49.7 0.3 1.7 1 1 0 1 1 1 1 Rad51 ATPase PF06745.13 AIM24239.1 - 6e-09 35.6 0.4 4e-07 29.6 0.4 2.6 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 AIM24239.1 - 0.0012 18.5 0.8 0.061 12.9 0.8 2.3 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 AIM24239.1 - 0.0018 18.3 0.0 0.003 17.5 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA PF00004.29 AIM24239.1 - 0.015 15.7 0.0 0.03 14.7 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 AIM24239.1 - 0.026 14.3 0.0 0.06 13.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain TK PF00265.18 AIM24239.1 - 0.029 14.3 0.0 0.044 13.7 0.0 1.2 1 0 0 1 1 1 0 Thymidine kinase AAA_16 PF13191.6 AIM24239.1 - 0.031 14.6 0.1 0.072 13.5 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain CobU PF02283.16 AIM24239.1 - 0.046 13.3 0.0 0.085 12.4 0.0 1.4 1 1 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase CbiA PF01656.23 AIM24239.1 - 0.067 13.2 0.0 0.11 12.6 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 AIM24239.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Peptidase_S24 PF00717.23 AIM24240.1 - 2.9e-11 43.2 0.0 3.9e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase S24-like IMS PF00817.20 AIM24241.1 - 1.9e-37 128.6 0.0 7.6e-37 126.6 0.0 2.0 2 0 0 2 2 2 1 impB/mucB/samB family DUF4113 PF13438.6 AIM24241.1 - 3.4e-16 59.0 0.1 7e-16 58.0 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4113) IMS_C PF11799.8 AIM24241.1 - 1.1e-15 58.3 0.1 2.5e-14 54.0 0.0 2.6 3 0 0 3 3 3 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 AIM24241.1 - 1.9e-05 24.7 0.0 5.6e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif DNA_pol_lambd_f PF10391.9 AIM24241.1 - 0.054 13.3 0.0 0.19 11.6 0.0 1.9 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda IncFII_repA PF02387.15 AIM24245.1 - 0.026 13.8 0.2 0.048 12.9 0.1 1.5 1 1 1 2 2 2 0 IncFII RepA protein family TraX PF05857.11 AIM24246.1 - 1.1e-30 107.4 7.6 1.3e-30 107.2 7.6 1.0 1 0 0 1 1 1 1 TraX protein PLDc_2 PF13091.6 AIM24247.1 - 1.1e-25 90.1 0.1 1.2e-25 89.9 0.1 1.1 1 0 0 1 1 1 1 PLD-like domain FAM83 PF07894.12 AIM24247.1 - 8.7e-05 22.2 0.0 0.00071 19.2 0.0 1.9 1 1 0 1 1 1 1 FAM83 A-H Regulator_TrmB PF11495.8 AIM24247.1 - 0.015 14.5 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB PP_kinase_C_1 PF17941.1 AIM24247.1 - 0.025 14.1 0.1 0.033 13.7 0.1 1.2 1 0 0 1 1 1 0 Polyphosphate kinase C-terminal domain 1 Isochorismatase PF00857.20 AIM24247.1 - 0.032 14.4 1.6 0.4 10.8 0.3 2.1 1 1 1 2 2 2 0 Isochorismatase family CopD PF05425.13 AIM24248.1 - 0.003 17.9 0.9 0.0036 17.7 0.9 1.1 1 0 0 1 1 1 1 Copper resistance protein D TrwC PF08751.11 AIM24249.1 - 5.4e-74 249.4 0.8 1.8e-73 247.7 0.8 2.0 1 0 0 1 1 1 1 TrwC relaxase AAA_30 PF13604.6 AIM24249.1 - 4e-35 121.3 17.5 3.3e-34 118.3 0.7 4.0 3 0 0 3 3 3 2 AAA domain TraI PF07057.11 AIM24249.1 - 1.2e-34 119.1 0.3 5e-34 117.1 0.3 2.2 1 0 0 1 1 1 1 DNA helicase TraI TraI_2B PF18340.1 AIM24249.1 - 7.3e-33 112.5 1.7 3.4e-31 107.1 0.9 2.9 2 0 0 2 2 2 1 DNA relaxase TraI 2B/2B-like domain ssDNA_TraI_N PF18272.1 AIM24249.1 - 4e-24 84.4 2.0 1.5e-23 82.5 0.5 2.9 3 0 0 3 3 3 1 single-stranded DNA binding TraI N-terminal subdomain AAA_19 PF13245.6 AIM24249.1 - 5.7e-11 42.9 0.5 2.6e-09 37.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 AIM24249.1 - 0.00017 21.4 0.1 0.00043 20.1 0.1 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_11 PF13086.6 AIM24249.1 - 0.026 14.3 0.0 0.58 9.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 AIM24249.1 - 0.031 14.5 0.1 0.74 10.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain Viral_DNA_bi PF02236.17 AIM24249.1 - 0.043 14.0 0.0 12 6.1 0.0 2.7 2 0 0 2 2 2 0 Viral DNA-binding protein, all alpha domain ABC_tran PF00005.27 AIM24249.1 - 0.24 11.9 1.6 27 5.3 0.0 3.6 2 1 1 3 3 3 0 ABC transporter TrwB_AAD_bind PF10412.9 AIM24250.1 - 8.1e-119 397.0 0.0 1e-118 396.6 0.0 1.1 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain TraG-D_C PF12696.7 AIM24250.1 - 1.6e-14 54.0 0.0 3.2e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TraD_N PF12615.8 AIM24250.1 - 1.2e-09 38.8 7.2 2.5e-09 37.8 7.2 1.6 1 0 0 1 1 1 1 F sex factor protein N terminal T4SS-DNA_transf PF02534.14 AIM24250.1 - 4e-06 25.9 0.0 4.7e-05 22.4 0.0 2.0 1 1 1 2 2 2 1 Type IV secretory system Conjugative DNA transfer PIF1 PF05970.14 AIM24250.1 - 0.044 12.9 0.0 0.063 12.4 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase Pilin_PilX PF11530.8 AIM24250.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Minor type IV pilin, PilX TraG_N PF07916.11 AIM24253.1 - 4.2e-89 299.6 15.7 4.2e-89 299.6 15.7 3.7 3 1 0 3 3 3 1 TraG-like protein, N-terminal region TraH PF06122.11 AIM24254.1 - 1.9e-109 366.3 1.4 2.5e-109 365.9 1.4 1.2 1 0 0 1 1 1 1 Conjugative relaxosome accessory transposon protein E1-E2_ATPase PF00122.20 AIM24255.1 - 0.01 15.3 0.3 0.014 14.9 0.3 1.1 1 0 0 1 1 1 0 E1-E2 ATPase Ureide_permease PF07168.11 AIM24255.1 - 0.24 10.1 3.2 0.44 9.2 0.6 2.0 2 0 0 2 2 2 0 Ureide permease YbhQ PF11076.8 AIM24255.1 - 0.35 10.9 5.0 0.85 9.6 1.0 2.1 2 0 0 2 2 2 0 Putative inner membrane protein YbhQ FtsX PF02687.21 AIM24255.1 - 8.1 7.0 9.6 4.9 7.7 2.0 2.1 1 1 1 2 2 2 0 FtsX-like permease family TraF PF13728.6 AIM24256.1 - 1e-08 35.3 0.0 1.6e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 AIM24256.1 - 0.0031 18.0 0.0 0.0055 17.1 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 AIM24256.1 - 0.058 13.1 0.0 0.17 11.6 0.0 1.8 1 1 2 3 3 3 0 Redoxin DSBA PF01323.20 AIM24256.1 - 0.099 12.4 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Glutaredoxin PF00462.24 AIM24256.1 - 0.14 12.4 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin Hydrolase_4 PF12146.8 AIM24256.1 - 0.15 11.3 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 TraQ PF09679.10 AIM24257.1 - 3.5e-25 87.7 0.0 4e-25 87.5 0.0 1.1 1 0 0 1 1 1 1 Type-F conjugative transfer system pilin chaperone (TraQ) TraF PF13728.6 AIM24258.1 - 1.8e-59 201.3 0.0 2.1e-59 201.1 0.0 1.0 1 0 0 1 1 1 1 F plasmid transfer operon protein TraN PF06986.11 AIM24259.1 - 3.1e-75 253.0 18.2 5.4e-75 252.2 18.2 1.3 1 0 0 1 1 1 1 Type-1V conjugative transfer system mating pair stabilisation TrbC_Ftype PF09673.10 AIM24260.1 - 9.9e-19 67.5 0.6 3.2e-18 65.8 0.0 2.2 3 1 0 3 3 3 1 Type-F conjugative transfer system pilin assembly protein BRF1 PF07741.13 AIM24260.1 - 0.042 14.2 0.2 0.2 12.0 0.2 1.9 1 1 0 1 1 1 0 Brf1-like TBP-binding domain TraU PF06834.11 AIM24261.1 - 2.5e-112 375.2 0.7 2.8e-112 375.0 0.7 1.0 1 0 0 1 1 1 1 TraU protein nec1 PF10379.9 AIM24261.1 - 0.18 11.3 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 Virulence protein nec1 HisKA_3 PF07730.13 AIM24262.1 - 0.0078 16.7 0.5 0.18 12.4 0.1 2.1 2 0 0 2 2 2 1 Histidine kinase DUF4948 PF16306.5 AIM24262.1 - 0.13 12.1 0.0 4.3 7.1 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4948) TraW_N PF12477.8 AIM24263.1 - 2e-05 24.4 0.1 4e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 Sex factor F TraW protein N terminal ScsC_N PF18312.1 AIM24264.1 - 5.8e-13 48.4 1.0 4.5e-12 45.6 0.7 2.3 2 0 0 2 2 2 1 Copper resistance protein ScsC N-terminal domain DSBA PF01323.20 AIM24264.1 - 2.1e-11 44.0 3.2 7.7e-10 38.9 3.2 2.3 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 AIM24264.1 - 5.2e-10 39.7 0.0 1.2e-09 38.5 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 AIM24264.1 - 5.2e-06 26.9 0.0 2.9e-05 24.5 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.20 AIM24264.1 - 0.0072 16.3 0.1 2.6 8.1 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin MHB PF16525.5 AIM24264.1 - 0.022 15.0 0.5 0.096 13.0 0.1 2.2 3 0 0 3 3 3 0 Haemophore, haem-binding HalOD1 PF18545.1 AIM24264.1 - 0.038 14.2 0.0 0.16 12.2 0.0 2.0 2 0 0 2 2 2 0 Halobacterial output domain 1 Thioredoxin_8 PF13905.6 AIM24264.1 - 0.1 12.9 0.1 2.6 8.5 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin-like TrbI_Ftype PF09677.10 AIM24265.1 - 2.4e-29 101.8 0.2 3.1e-29 101.4 0.2 1.2 1 0 0 1 1 1 1 Type-F conjugative transfer system protein (TrbI_Ftype) TraC_F_IV PF11130.8 AIM24266.1 - 2.9e-45 154.7 0.0 6.5e-45 153.6 0.0 1.6 1 0 0 1 1 1 1 F pilus assembly Type-IV secretion system for plasmid transfer AAA_10 PF12846.7 AIM24266.1 - 1e-05 24.7 0.1 0.00015 20.8 0.1 2.1 2 0 0 2 2 2 1 AAA-like domain DUF87 PF01935.17 AIM24266.1 - 4.2e-05 23.7 0.8 0.00027 21.1 0.0 2.6 4 0 0 4 4 4 1 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 AIM24266.1 - 0.0012 17.9 0.1 0.0032 16.4 0.0 1.7 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain T4SS-DNA_transf PF02534.14 AIM24266.1 - 0.0016 17.3 0.9 0.0033 16.3 0.5 1.7 1 1 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraV PF09676.10 AIM24268.1 - 8.7e-28 97.9 0.3 1.1e-27 97.6 0.3 1.1 1 0 0 1 1 1 1 Type IV conjugative transfer system lipoprotein (TraV) 7TMR-DISM_7TM PF07695.11 AIM24269.1 - 0.0015 18.5 5.7 0.0017 18.3 5.7 1.1 1 0 0 1 1 1 1 7TM diverse intracellular signalling AAA_22 PF13401.6 AIM24270.1 - 0.00032 21.0 0.0 0.00036 20.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 AIM24270.1 - 0.001 19.0 0.0 0.0013 18.7 0.0 1.1 1 0 0 1 1 1 1 NACHT domain AAA_30 PF13604.6 AIM24270.1 - 0.0011 18.7 0.0 0.0012 18.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 AIM24270.1 - 0.0013 19.3 0.0 0.0013 19.2 0.0 1.1 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 AIM24270.1 - 0.0038 16.6 0.0 0.0041 16.5 0.0 1.1 1 0 0 1 1 1 1 FtsK/SpoIIIE family NB-ARC PF00931.22 AIM24270.1 - 0.0074 15.5 0.0 0.0091 15.2 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_23 PF13476.6 AIM24270.1 - 0.0089 16.5 0.0 0.0094 16.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 AIM24270.1 - 0.013 15.1 0.0 0.014 15.0 0.0 1.1 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 AIM24270.1 - 0.013 15.5 0.1 0.021 14.8 0.1 1.4 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MMR_HSR1 PF01926.23 AIM24270.1 - 0.018 15.1 0.0 0.021 14.9 0.0 1.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 AIM24270.1 - 0.02 14.8 0.0 0.022 14.6 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase RNA_helicase PF00910.22 AIM24270.1 - 0.021 15.2 0.0 0.031 14.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 AIM24270.1 - 0.021 14.7 0.0 0.023 14.6 0.0 1.1 1 0 0 1 1 1 0 NTPase AAA_7 PF12775.7 AIM24270.1 - 0.022 14.3 0.0 0.025 14.1 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region Roc PF08477.13 AIM24270.1 - 0.024 14.8 0.0 0.03 14.5 0.0 1.1 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase T2SSE PF00437.20 AIM24270.1 - 0.029 13.4 0.0 0.031 13.3 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 AIM24270.1 - 0.029 14.1 0.0 0.039 13.7 0.0 1.2 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.18 AIM24270.1 - 0.03 13.6 0.0 0.032 13.5 0.0 1.1 1 0 0 1 1 1 0 Septin DUF87 PF01935.17 AIM24270.1 - 0.031 14.4 0.0 0.038 14.1 0.0 1.1 1 0 0 1 1 1 0 Helicase HerA, central domain GTP_EFTU PF00009.27 AIM24270.1 - 0.033 13.7 0.0 0.034 13.7 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 AIM24270.1 - 0.033 13.9 0.0 0.039 13.7 0.0 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.6 AIM24270.1 - 0.052 13.7 0.0 0.062 13.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 AIM24270.1 - 0.057 13.2 0.0 0.065 13.0 0.0 1.1 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.6 AIM24270.1 - 0.072 13.5 0.1 0.086 13.3 0.1 1.1 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 AIM24270.1 - 0.072 13.0 0.0 0.09 12.7 0.0 1.1 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.17 AIM24270.1 - 0.092 12.5 0.1 0.11 12.3 0.1 1.1 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein PLA2_B PF01735.18 AIM24270.1 - 0.094 11.1 0.0 0.094 11.1 0.0 1.0 1 0 0 1 1 1 0 Lysophospholipase catalytic domain DUF853 PF05872.12 AIM24270.1 - 0.13 10.8 0.2 0.15 10.6 0.2 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Zeta_toxin PF06414.12 AIM24270.1 - 0.15 11.3 0.0 0.2 10.9 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin Viral_helicase1 PF01443.18 AIM24270.1 - 0.16 11.6 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 AIM24270.1 - 0.17 11.8 0.0 0.2 11.6 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 AIM24270.1 - 0.19 11.5 0.1 0.21 11.3 0.1 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.9 AIM24270.1 - 0.2 10.8 0.0 0.23 10.7 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TrbI PF03743.14 AIM24271.1 - 4.4e-28 98.4 1.7 4.4e-28 98.4 1.7 1.9 2 0 0 2 2 2 1 Bacterial conjugation TrbI-like protein HemX PF04375.14 AIM24271.1 - 0.021 14.2 4.0 0.041 13.2 4.0 1.4 1 1 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF5082 PF16888.5 AIM24271.1 - 0.69 10.2 4.1 0.36 11.1 1.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) TraK PF06586.11 AIM24272.1 - 3.5e-39 134.8 0.0 4.1e-39 134.6 0.0 1.0 1 0 0 1 1 1 1 TraK protein TraE PF05309.11 AIM24273.1 - 4.8e-51 172.7 1.1 5.4e-51 172.6 1.1 1.0 1 0 0 1 1 1 1 TraE protein Saf_2TM PF18303.1 AIM24273.1 - 0.094 12.3 2.2 0.095 12.3 0.7 1.7 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain DUF2393 PF09624.10 AIM24273.1 - 0.46 10.5 3.0 0.92 9.5 3.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2393) TraL PF07178.11 AIM24274.1 - 8.3e-27 93.5 1.5 9.2e-27 93.4 1.5 1.0 1 0 0 1 1 1 1 TraL protein Iron_traffic PF04362.14 AIM24274.1 - 0.11 12.2 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 Bacterial Fe(2+) trafficking ArfA PF03889.13 AIM24274.1 - 0.15 11.5 0.5 0.36 10.3 0.0 1.8 2 0 0 2 2 2 0 Alternative ribosome-rescue factor A TraA PF05513.11 AIM24275.1 - 3.9e-38 130.5 7.2 4.3e-38 130.4 7.2 1.0 1 0 0 1 1 1 1 TraA Bac_export_2 PF01312.19 AIM24275.1 - 0.017 14.3 1.1 0.02 14.1 1.1 1.2 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family QueC PF06508.13 AIM24276.1 - 4.5e-83 277.9 0.1 5.2e-83 277.7 0.1 1.0 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC NAD_synthase PF02540.17 AIM24276.1 - 0.00031 19.9 0.0 0.0018 17.5 0.0 1.9 2 0 0 2 2 2 1 NAD synthase Asn_synthase PF00733.21 AIM24276.1 - 0.00045 20.0 0.1 0.00058 19.6 0.1 1.1 1 0 0 1 1 1 1 Asparagine synthase ATP_bind_3 PF01171.20 AIM24276.1 - 0.0016 18.3 0.1 0.0079 16.0 0.1 1.9 2 0 0 2 2 2 1 PP-loop family ThiI PF02568.14 AIM24276.1 - 0.0039 16.8 0.0 0.34 10.5 0.0 2.2 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) Arginosuc_synth PF00764.19 AIM24276.1 - 0.0071 15.7 0.1 0.01 15.2 0.1 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase PAPS_reduct PF01507.19 AIM24276.1 - 0.01 15.9 0.0 0.034 14.2 0.0 1.8 2 0 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family Diphthami_syn_2 PF01902.17 AIM24276.1 - 0.09 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Diphthamide synthase Cys_rich_VLP PF14194.6 AIM24276.1 - 0.65 10.2 4.2 6.6 6.9 0.0 2.3 2 0 0 2 2 2 0 Cysteine-rich VLP Vut_1 PF02592.15 AIM24277.1 - 6.3e-36 124.0 12.8 6.3e-36 124.0 12.8 1.8 2 0 0 2 2 2 1 Putative vitamin uptake transporter HTH_26 PF13443.6 AIM24278.1 - 6.8e-06 26.4 0.0 1.1e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_3 PF01381.22 AIM24278.1 - 9.3e-05 22.4 0.0 0.00016 21.7 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 AIM24278.1 - 0.00041 20.3 0.0 0.00067 19.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.19 AIM24278.1 - 0.037 13.9 0.1 0.079 12.8 0.1 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_31 PF13560.6 AIM24278.1 - 0.041 14.2 0.0 0.066 13.6 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain IZUMO PF15005.6 AIM24278.1 - 0.21 12.1 0.0 0.36 11.3 0.0 1.4 1 0 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated HTH_19 PF12844.7 AIM24279.1 - 7.3e-13 48.3 0.0 2.3e-12 46.7 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 AIM24279.1 - 8.8e-12 44.9 0.0 2.2e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 AIM24279.1 - 1.4e-06 28.5 0.0 2.9e-06 27.5 0.0 1.4 2 0 0 2 2 2 1 Helix-turn-helix domain MqsA_antitoxin PF15731.5 AIM24279.1 - 0.017 15.2 0.0 0.03 14.4 0.0 1.3 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA Pou PF00157.17 AIM24279.1 - 0.15 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Pou domain - N-terminal to homeobox domain Tra_M PF05261.11 AIM24280.1 - 3.2e-50 169.3 0.9 3.7e-50 169.1 0.9 1.0 1 0 0 1 1 1 1 TraM protein, DNA-binding RHH_5 PF07878.11 AIM24280.1 - 0.02 14.8 0.3 0.35 10.8 0.3 2.3 1 1 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 Tim44 PF04280.15 AIM24280.1 - 0.089 12.9 0.4 3.6 7.7 0.0 2.1 2 0 0 2 2 2 0 Tim44-like domain SLT PF01464.20 AIM24281.1 - 1.1e-25 89.5 0.0 1.5e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Transglycosylase SLT domain Glucosaminidase PF01832.20 AIM24281.1 - 0.0011 19.5 0.1 0.0015 18.9 0.1 1.3 1 0 0 1 1 1 1 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase RNase_H PF00075.24 AIM24281.1 - 0.097 12.8 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 RNase H DUF932 PF06067.11 AIM24282.1 - 2.4e-56 191.1 0.0 2.8e-56 190.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF932) N6_Mtase PF02384.16 AIM24284.1 - 2.2e-08 33.8 0.0 3.1e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase CBM_5_12_2 PF14600.6 AIM24285.1 - 0.65 10.0 2.6 1.4 9.0 1.4 2.0 2 0 0 2 2 2 0 Cellulose-binding domain PsiA PF06952.11 AIM24286.1 - 1.5e-33 116.1 1.3 1.6e-33 115.9 1.3 1.0 1 0 0 1 1 1 1 PsiA protein PsiB PF06290.11 AIM24287.1 - 1.7e-49 166.8 0.0 2e-49 166.7 0.0 1.0 1 0 0 1 1 1 1 Plasmid SOS inhibition protein (PsiB) HTH_23 PF13384.6 AIM24288.1 - 0.014 15.2 0.1 0.07 13.0 0.0 2.2 2 0 0 2 2 2 0 Homeodomain-like domain ParBc PF02195.18 AIM24288.1 - 0.087 13.1 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 ParB-like nuclease domain VirC1 PF07015.11 AIM24290.1 - 1.9e-06 27.4 0.0 3.3e-06 26.6 0.0 1.4 1 1 0 1 1 1 1 VirC1 protein MipZ PF09140.11 AIM24290.1 - 0.034 13.4 0.2 0.045 13.0 0.2 1.5 1 1 0 1 1 1 0 ATPase MipZ Sec34 PF04136.15 AIM24291.1 - 0.1 12.5 0.2 0.12 12.2 0.2 1.1 1 0 0 1 1 1 0 Sec34-like family Resolvase PF00239.21 AIM24292.1 - 1.4e-39 135.5 3.2 2e-39 135.0 3.2 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_7 PF02796.15 AIM24292.1 - 3.6e-09 36.6 0.1 7.5e-09 35.5 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 AIM24292.1 - 5.4e-08 32.4 0.1 1.3e-07 31.3 0.1 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 AIM24292.1 - 0.00013 22.0 1.1 0.00025 21.0 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 AIM24292.1 - 0.00018 21.6 0.1 0.00018 21.6 0.1 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 AIM24292.1 - 0.0003 20.7 0.8 0.0021 18.0 0.0 2.4 2 1 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_22 PF13309.6 AIM24292.1 - 0.0018 18.3 0.1 0.014 15.5 0.0 2.3 2 0 0 2 2 2 1 HTH domain HTH_IclR PF09339.10 AIM24292.1 - 0.016 15.0 0.0 0.049 13.5 0.0 1.8 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 AIM24292.1 - 0.019 14.4 1.0 0.04 13.3 0.1 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_3 PF01381.22 AIM24292.1 - 0.023 14.8 1.3 0.03 14.4 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix HTH_31 PF13560.6 AIM24292.1 - 0.03 14.7 6.2 0.13 12.6 6.2 2.2 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_IS1 PF12759.7 AIM24292.1 - 0.054 13.1 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 InsA C-terminal domain Barstar PF01337.18 AIM24292.1 - 0.062 13.3 0.3 0.33 11.0 0.3 2.1 1 1 0 1 1 1 0 Barstar (barnase inhibitor) Phage_AlpA PF05930.12 AIM24292.1 - 0.069 13.0 0.1 0.21 11.5 0.0 1.9 2 0 0 2 2 2 0 Prophage CP4-57 regulatory protein (AlpA) TrmB PF01978.19 AIM24292.1 - 0.096 12.6 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB GerE PF00196.19 AIM24292.1 - 0.1 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_19 PF12844.7 AIM24292.1 - 0.11 12.6 0.0 0.29 11.2 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_32 PF13565.6 AIM24292.1 - 0.16 12.6 4.5 0.11 13.2 1.9 2.1 2 1 0 2 2 2 0 Homeodomain-like domain Transposase_31 PF04754.12 AIM24293.1 - 5.5e-87 290.6 0.0 7.7e-87 290.2 0.0 1.2 1 0 0 1 1 1 1 Putative transposase, YhgA-like DUF2956 PF11169.8 AIM24293.1 - 0.012 15.7 2.0 0.02 15.1 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) LPD23 PF18838.1 AIM24293.1 - 0.061 13.1 2.4 0.22 11.3 0.1 2.6 3 0 0 3 3 3 0 Large polyvalent protein associated domain 23 Yae1_N PF09811.9 AIM24293.1 - 0.37 10.5 9.9 0.71 9.6 9.9 1.5 1 0 0 1 1 1 0 Essential protein Yae1, N terminal DUF2913 PF11140.8 AIM24294.1 - 6.7e-16 58.7 0.0 7.9e-16 58.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2913) PerC PF06069.11 AIM24295.1 - 1.5e-10 41.2 0.2 1.6e-10 41.1 0.2 1.1 1 0 0 1 1 1 1 PerC transcriptional activator DUF883 PF05957.13 AIM24296.1 - 2.1e-14 53.9 0.7 2.7e-14 53.5 0.7 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) CsbD PF05532.12 AIM24296.1 - 1e-08 35.0 10.9 1.3e-08 34.6 10.9 1.1 1 0 0 1 1 1 1 CsbD-like V-ATPase_G_2 PF16999.5 AIM24296.1 - 0.0079 16.6 2.5 0.0093 16.4 2.5 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit Apolipoprotein PF01442.18 AIM24296.1 - 0.011 15.6 0.3 0.013 15.4 0.3 1.0 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain baeRF_family10 PF18854.1 AIM24296.1 - 0.05 13.9 0.4 0.065 13.5 0.4 1.1 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 10 HTH_Tnp_1 PF01527.20 AIM24297.1 - 4.5e-12 46.1 0.3 5.6e-12 45.8 0.3 1.2 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 AIM24297.1 - 8.7e-07 28.6 0.0 4.1e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 AIM24297.1 - 1.9e-06 27.9 0.0 2.9e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_1 PF00126.27 AIM24297.1 - 0.00089 19.2 0.4 0.0018 18.2 0.0 1.8 2 1 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_3 PF01381.22 AIM24297.1 - 0.0014 18.6 0.9 0.0065 16.5 0.0 2.3 2 1 0 2 2 2 1 Helix-turn-helix P22_Cro PF14549.6 AIM24297.1 - 0.0093 15.8 0.1 0.014 15.2 0.1 1.3 1 0 0 1 1 1 1 DNA-binding transcriptional regulator Cro HTH_29 PF13551.6 AIM24297.1 - 0.028 14.4 0.0 0.048 13.7 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix Trp_repressor PF01371.19 AIM24297.1 - 0.029 14.5 0.2 0.093 12.9 0.0 1.7 2 0 0 2 2 2 0 Trp repressor protein HTH_31 PF13560.6 AIM24297.1 - 0.055 13.8 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain LapA_dom PF06305.11 AIM24297.1 - 1.3 8.9 3.3 1.9 8.4 3.3 1.4 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain rve PF00665.26 AIM24298.1 - 3.7e-31 107.8 0.2 5.6e-31 107.2 0.2 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 AIM24298.1 - 2.8e-12 46.2 0.1 5.1e-12 45.4 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 AIM24298.1 - 6.7e-07 29.6 0.0 9.8e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 DDE domain rve_2 PF13333.6 AIM24298.1 - 0.00013 22.1 0.5 0.00026 21.1 0.1 1.7 2 0 0 2 2 2 1 Integrase core domain HTH_21 PF13276.6 AIM24298.1 - 0.0011 19.0 0.1 0.0023 18.0 0.1 1.5 1 0 0 1 1 1 1 HTH-like domain DUF883 PF05957.13 AIM24299.1 - 0.0055 17.3 11.8 0.51 11.0 0.6 2.1 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 AIM24299.1 - 0.028 14.9 14.0 0.14 12.7 3.0 2.1 1 1 1 2 2 2 0 YtxH-like protein DUF842 PF05811.13 AIM24299.1 - 0.068 12.9 3.6 0.085 12.6 3.6 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) LEA_4 PF02987.16 AIM24299.1 - 0.66 10.1 19.6 1.5 9.0 4.7 2.8 2 1 0 2 2 2 0 Late embryogenesis abundant protein MT0933_antitox PF14013.6 AIM24299.1 - 2.1 8.7 13.3 2.1e+03 -0.9 13.3 2.9 1 1 0 1 1 1 0 MT0933-like antitoxin protein Borrelia_P83 PF05262.11 AIM24299.1 - 6.3 5.2 16.2 7.5 4.9 16.2 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Phage_holin_3_6 PF07332.11 AIM24300.1 - 1.1e-16 60.9 5.8 1.2e-16 60.7 5.8 1.0 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III MARVEL PF01284.23 AIM24300.1 - 0.0066 16.5 1.4 0.0074 16.3 1.4 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF1772 PF08592.11 AIM24300.1 - 0.044 14.1 0.5 0.049 13.9 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) DUF2207 PF09972.9 AIM24300.1 - 0.14 10.9 0.2 0.14 10.9 0.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) YqjK PF13997.6 AIM24301.1 - 7.1e-18 64.6 5.5 9.2e-18 64.3 5.5 1.1 1 0 0 1 1 1 1 YqjK-like protein DUF903 PF06004.12 AIM24303.1 - 2.8e-14 52.7 0.3 3.3e-14 52.5 0.3 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF903) DUF4179 PF13786.6 AIM24303.1 - 0.045 14.2 0.1 0.053 14.0 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) DUF3792 PF12670.7 AIM24304.1 - 0.0016 18.6 9.4 0.0016 18.6 9.4 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3792) YmgB PF10798.8 AIM24304.1 - 0.0043 16.8 0.1 0.013 15.3 0.1 1.8 1 0 0 1 1 1 1 Biofilm development protein YmgB/AriR LMBR1 PF04791.16 AIM24304.1 - 0.016 14.1 0.0 0.019 13.9 0.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein MCU PF04678.13 AIM24304.1 - 0.016 15.3 0.9 0.022 14.8 0.9 1.3 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF3486 PF11985.8 AIM24304.1 - 0.032 14.6 7.5 0.046 14.1 7.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3486) EspB PF05802.11 AIM24304.1 - 0.033 14.2 7.5 0.072 13.1 6.8 2.1 1 1 0 1 1 1 0 Enterobacterial EspB protein DUF2381 PF09544.10 AIM24304.1 - 0.035 13.6 3.1 0.051 13.1 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2381) EMP24_GP25L PF01105.24 AIM24304.1 - 0.038 13.9 0.3 0.038 13.9 0.3 2.3 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Spc7 PF08317.11 AIM24304.1 - 0.16 10.8 8.9 0.24 10.3 8.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Apolipoprotein PF01442.18 AIM24304.1 - 0.56 10.1 13.7 1.4 8.7 13.7 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain KfrA_N PF11740.8 AIM24304.1 - 0.58 10.8 13.0 1.2 9.9 12.0 1.9 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term Nuc_sug_transp PF04142.15 AIM24304.1 - 0.71 9.0 7.8 2.3 7.3 4.2 2.1 2 0 0 2 2 2 0 Nucleotide-sugar transporter Peripla_BP_2 PF01497.18 AIM24304.1 - 0.84 9.1 7.8 1.3 8.5 6.9 1.7 1 1 1 2 2 2 0 Periplasmic binding protein Fib_alpha PF08702.10 AIM24304.1 - 1.7 8.8 6.5 3.2 7.9 6.5 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Muted PF14942.6 AIM24304.1 - 2 8.7 9.1 0.96 9.8 4.7 2.1 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein DUF4337 PF14235.6 AIM24304.1 - 2.7 8.1 13.9 1.8 8.7 9.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) DUF4795 PF16043.5 AIM24304.1 - 4.7 6.8 17.8 6.7 6.3 15.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Mod_r PF07200.13 AIM24304.1 - 4.9 7.3 11.4 14 5.8 9.2 2.3 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Med2 PF11214.8 AIM24304.1 - 5.1 7.3 10.0 3.9 7.7 7.7 1.9 1 1 1 2 2 2 0 Mediator complex subunit 2 ISG65-75 PF11727.8 AIM24304.1 - 5.3 6.2 11.4 9.4 5.4 11.4 1.4 1 0 0 1 1 1 0 Invariant surface glycoprotein DltD PF04914.12 AIM24304.1 - 7.1 5.9 9.5 9.8 5.4 9.5 1.1 1 0 0 1 1 1 0 DltD protein DUF4199 PF13858.6 AIM24304.1 - 9.3 6.6 13.5 1.3 9.4 0.5 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF4199) DUF421 PF04239.12 AIM24305.1 - 1.1e-22 79.8 0.0 4.9e-22 77.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF421) HcyBio PF01837.16 AIM24305.1 - 0.014 14.2 0.0 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 Homocysteine biosynthesis enzyme, sulfur-incorporation DUF4203 PF13886.6 AIM24305.1 - 0.036 13.7 5.0 0.051 13.2 5.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) Peptidase_U4 PF03419.13 AIM24305.1 - 0.04 13.2 3.9 0.054 12.8 3.9 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Catalase_C PF18011.1 AIM24306.1 - 1.3e-10 41.1 0.0 1.5e-10 40.9 0.0 1.0 1 0 0 1 1 1 1 C-terminal domain found in long catalases Transposase_31 PF04754.12 AIM24310.1 - 4.7e-86 287.6 0.0 6.9e-86 287.1 0.0 1.2 1 0 0 1 1 1 1 Putative transposase, YhgA-like LPD23 PF18838.1 AIM24310.1 - 0.02 14.6 1.5 0.12 12.2 0.1 2.6 3 0 0 3 3 3 0 Large polyvalent protein associated domain 23 Yae1_N PF09811.9 AIM24310.1 - 0.021 14.5 10.9 0.038 13.7 10.9 1.4 1 0 0 1 1 1 0 Essential protein Yae1, N terminal CRAL_TRIO_2 PF13716.6 AIM24310.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain DUF2913 PF11140.8 AIM24311.1 - 5.3e-17 62.2 0.0 6.4e-17 62.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2913) # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Serratia_sp._SCBI-ASM74756v1/GCA_000747565.1_ASM74756v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Serratia_sp._SCBI-ASM74756v1/GCA_000747565.1_ASM74756v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Serratia_sp._SCBI-ASM74756v1/GCA_000747565.1_ASM74756v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Serratia_sp._SCBI-ASM74756v1/GCA_000747565.1_ASM74756v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 04:38:51 2019 # [ok]