# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- PaREP1 PF05942.11 AAL62494.1 - 3.3e-29 101.1 1.2 4.1e-29 100.8 1.2 1.1 1 0 0 1 1 1 1 Archaeal PaREP1/PaREP8 family Rossmann-like PF10727.9 AAL62494.1 - 0.029 14.2 0.2 0.042 13.7 0.2 1.3 1 0 0 1 1 1 0 Rossmann-like domain Peptidase_M19 PF01244.21 AAL62495.1 - 1.1e-87 294.3 0.0 1.2e-87 294.1 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Amidohydro_2 PF04909.14 AAL62495.1 - 0.0022 17.8 0.0 0.0058 16.4 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase DUF4253 PF14062.6 AAL62495.1 - 0.16 12.1 0.0 0.43 10.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4253) AAA_15 PF13175.6 AAL62496.1 - 1.4e-25 90.9 0.0 7.4e-15 55.5 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 AAL62496.1 - 2e-16 60.7 0.0 4.3e-11 43.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF2813 PF11398.8 AAL62496.1 - 9.2e-05 21.9 0.0 0.028 13.7 0.0 2.5 3 0 0 3 3 3 2 Protein of unknown function (DUF2813) AAA_23 PF13476.6 AAL62496.1 - 0.0099 16.4 0.0 0.016 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_27 PF13514.6 AAL62496.1 - 0.011 15.3 0.1 0.82 9.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 AAL62496.1 - 0.16 12.1 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 AAL62496.1 - 0.16 11.4 0.0 1.8 7.9 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain CSD2 PF17876.1 AAL62497.1 - 0.087 13.0 0.2 0.12 12.6 0.2 1.2 1 0 0 1 1 1 0 Cold shock domain Exonuc_VII_S PF02609.16 AAL62498.1 - 0.014 15.5 2.8 0.014 15.5 2.8 2.0 2 1 0 2 2 2 0 Exonuclease VII small subunit DUF892 PF05974.12 AAL62498.1 - 0.017 15.2 0.2 0.017 15.2 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF892) FliS PF02561.14 AAL62498.1 - 0.025 14.8 0.1 0.03 14.6 0.1 1.1 1 0 0 1 1 1 0 Flagellar protein FliS HisKA_3 PF07730.13 AAL62498.1 - 0.025 15.1 0.2 0.47 11.0 0.0 2.0 2 0 0 2 2 2 0 Histidine kinase DUF4175 PF13779.6 AAL62498.1 - 0.048 11.6 0.1 0.048 11.6 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF4363 PF14276.6 AAL62498.1 - 0.063 13.4 0.1 0.07 13.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) Arm-DNA-bind_4 PF14657.6 AAL62498.1 - 0.13 12.0 0.1 0.18 11.6 0.1 1.2 1 0 0 1 1 1 0 Arm DNA-binding domain Radical_SAM PF04055.21 AAL62499.1 - 1.1e-11 45.5 0.0 1.4e-11 45.0 0.0 1.4 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 AAL62499.1 - 3e-11 43.5 0.0 3.9e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 AAL62499.1 - 2.1e-09 37.8 0.0 2.9e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 4Fe-4S single cluster domain zf-CHCC PF10276.9 AAL62499.1 - 0.02 15.0 0.3 0.037 14.1 0.3 1.4 1 0 0 1 1 1 0 Zinc-finger domain STAT1_TAZ2bind PF12162.8 AAL62499.1 - 0.46 10.1 2.2 0.55 9.9 0.0 2.1 2 0 0 2 2 2 0 STAT1 TAZ2 binding domain PadR PF03551.14 AAL62501.1 - 1.3e-15 57.1 0.0 2.5e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_45 PF14947.6 AAL62501.1 - 0.03 14.3 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix HTH_27 PF13463.6 AAL62501.1 - 0.039 14.5 0.1 0.45 11.1 0.0 2.4 3 0 0 3 3 3 0 Winged helix DNA-binding domain Mrr_N PF14338.6 AAL62501.1 - 0.083 13.0 0.0 0.29 11.3 0.0 1.8 2 0 0 2 2 2 0 Mrr N-terminal domain DprA_WH PF17782.1 AAL62501.1 - 0.12 12.5 0.0 0.65 10.1 0.0 2.1 1 1 0 1 1 1 0 DprA winged helix domain DUF505 PF04458.12 AAL62501.1 - 0.14 10.5 0.0 0.14 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF505) MarR PF01047.22 AAL62501.1 - 0.16 11.9 0.0 0.57 10.2 0.0 1.9 2 0 0 2 2 2 0 MarR family DUF4097 PF13349.6 AAL62502.1 - 6.1e-06 25.8 0.0 8.2e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Putative adhesin bZIP_2 PF07716.15 AAL62504.1 - 0.035 14.2 0.4 0.036 14.1 0.4 1.1 1 0 0 1 1 1 0 Basic region leucine zipper COMP PF11598.8 AAL62504.1 - 0.042 14.3 0.7 0.042 14.3 0.7 1.1 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein ASCH PF04266.14 AAL62505.1 - 0.15 12.6 0.0 0.17 12.5 0.0 1.2 1 0 0 1 1 1 0 ASCH domain DUF3850 PF12961.7 AAL62505.1 - 0.2 11.7 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3850) PBP_like PF12727.7 AAL62506.1 - 3.1e-30 104.8 0.0 4.6e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 PBP superfamily domain HTH_1 PF00126.27 AAL62506.1 - 2.8e-14 52.8 0.7 6.6e-14 51.6 0.1 1.9 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 AAL62506.1 - 9.8e-05 21.8 0.0 0.00043 19.7 0.0 1.8 1 1 1 2 2 2 1 LysR substrate binding domain HTH_Tnp_ISL3 PF13542.6 AAL62506.1 - 0.15 11.5 0.0 1.3 8.5 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 PBP_like_2 PF12849.7 AAL62507.1 - 2e-19 70.3 0.1 2.7e-19 69.9 0.1 1.1 1 0 0 1 1 1 1 PBP superfamily domain SBP_bac_11 PF13531.6 AAL62507.1 - 0.00012 21.9 0.0 0.00016 21.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein PBP_like PF12727.7 AAL62507.1 - 0.0076 15.4 0.0 0.018 14.2 0.0 1.6 1 1 0 1 1 1 1 PBP superfamily domain LysR_substrate PF03466.20 AAL62507.1 - 0.0098 15.3 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 LysR substrate binding domain Adenyl_cycl_N PF12633.7 AAL62507.1 - 0.028 14.3 0.0 0.077 12.9 0.0 1.6 2 0 0 2 2 2 0 Adenylate cyclase NT domain DUF2807 PF10988.8 AAL62507.1 - 0.13 12.0 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative auto-transporter adhesin, head GIN domain BPD_transp_1 PF00528.22 AAL62508.1 - 4.8e-08 33.0 15.7 4.8e-08 33.0 15.7 1.3 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 AAL62509.1 - 1.8e-26 93.3 0.0 2.3e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAL62509.1 - 1.5e-11 44.7 0.0 5e-06 26.5 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAL62509.1 - 2.4e-10 40.2 0.0 7.1e-05 22.3 0.0 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 AAL62509.1 - 4.2e-07 30.0 0.0 2.8e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 AAL62509.1 - 1.8e-06 28.6 0.0 2.8e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAL62509.1 - 8e-05 22.3 0.0 0.00014 21.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_5 PF07728.14 AAL62509.1 - 0.00033 20.7 0.0 0.00057 19.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 AAL62509.1 - 0.001 19.3 0.0 0.0018 18.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AAL62509.1 - 0.0016 18.2 0.0 0.003 17.3 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 AAL62509.1 - 0.0034 17.0 0.0 0.008 15.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 AAL62509.1 - 0.006 16.5 0.0 0.014 15.4 0.0 1.5 2 0 0 2 2 2 1 NACHT domain SRP54 PF00448.22 AAL62509.1 - 0.0097 15.6 0.0 0.079 12.6 0.0 2.2 1 1 1 2 2 2 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 AAL62509.1 - 0.011 16.1 0.0 0.012 16.0 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 AAL62509.1 - 0.014 15.5 0.0 0.044 13.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 AAL62509.1 - 0.035 14.5 0.0 0.1 13.0 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 AAL62509.1 - 0.039 13.0 0.0 0.049 12.7 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_13 PF13166.6 AAL62509.1 - 0.072 11.7 0.0 0.086 11.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 AAL62509.1 - 0.086 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain SbcCD_C PF13558.6 AAL62509.1 - 0.097 12.9 0.0 1.9 8.8 0.0 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF3584 PF12128.8 AAL62509.1 - 0.098 10.2 0.0 0.13 9.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) cobW PF02492.19 AAL62509.1 - 0.1 12.2 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 AAL62509.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 AAL62509.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea TsaE PF02367.17 AAL62509.1 - 0.16 12.0 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 AAL62509.1 - 0.19 11.7 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AAL62509.1 - 0.2 11.4 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 AAL62509.1 - 0.21 12.0 0.0 0.58 10.6 0.0 1.8 2 0 0 2 2 2 0 RNA helicase G-alpha PF00503.20 AAL62509.1 - 0.22 10.6 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit adh_short_C2 PF13561.6 AAL62510.1 - 1.3e-38 132.9 0.2 2.7e-38 131.9 0.2 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAL62510.1 - 2.1e-34 118.7 0.0 2.7e-34 118.4 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAL62510.1 - 5.9e-07 29.6 0.0 9e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 AAL62510.1 - 0.0017 17.7 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) ATP-cone PF03477.16 AAL62511.1 - 5.4e-09 36.5 1.7 6.7e-09 36.2 1.7 1.3 1 1 0 1 1 1 1 ATP cone domain MHCassoc_trimer PF08831.10 AAL62511.1 - 0.029 14.4 0.2 0.046 13.7 0.2 1.4 1 0 0 1 1 1 0 Class II MHC-associated invariant chain trimerisation domain Polbeta PF18765.1 AAL62512.1 - 8.6e-11 41.8 0.0 1.7e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase DUF86 PF01934.17 AAL62512.1 - 1.8e-09 37.5 0.1 3.1e-09 36.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF86 DUF402 PF04167.13 AAL62513.1 - 5.7e-12 45.7 0.7 9.9e-12 44.9 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF402) RNase_E_G PF10150.9 AAL62513.1 - 0.13 11.7 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribonuclease E/G family DUF2969 PF11184.8 AAL62514.1 - 0.0061 16.9 0.1 0.011 16.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2969) Paz_1 PF18349.1 AAL62514.1 - 0.14 12.1 2.2 0.62 10.1 2.2 1.9 1 1 0 1 1 1 0 PAZ domain DpnD-PcfM PF14207.6 AAL62514.1 - 2.6 8.0 5.0 0.28 11.1 0.6 1.6 2 0 0 2 2 2 0 DpnD/PcfM-like protein PIN PF01850.21 AAL62515.1 - 1.7e-11 44.7 1.0 8.6e-11 42.4 1.0 1.8 1 1 0 1 1 1 1 PIN domain GHMP_kinases_N PF00288.26 AAL62516.1 - 1.1e-11 44.8 2.5 3.4e-11 43.2 2.5 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 AAL62516.1 - 2.5e-10 40.6 0.3 2.5e-10 40.6 0.3 2.0 3 0 0 3 3 3 1 GHMP kinases C terminal Cyclase PF04199.13 AAL62517.1 - 7.8e-28 97.4 0.0 9.6e-28 97.1 0.0 1.1 1 0 0 1 1 1 1 Putative cyclase FtsX PF02687.21 AAL62518.1 - 7e-09 36.0 7.6 7e-09 36.0 7.6 2.9 3 0 0 3 3 3 1 FtsX-like permease family MacB_PCD PF12704.7 AAL62518.1 - 2.7e-08 34.4 3.4 2.7e-08 34.4 3.4 2.2 2 0 0 2 2 2 1 MacB-like periplasmic core domain YtpI PF14007.6 AAL62518.1 - 9.2 6.5 9.2 0.58 10.3 1.4 2.9 3 0 0 3 3 3 0 YtpI-like protein DUF4199 PF13858.6 AAL62520.1 - 0.0012 19.2 0.2 0.0012 19.2 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF4199) Romo1 PF10247.9 AAL62520.1 - 0.0058 17.0 5.3 0.041 14.3 0.3 2.3 2 0 0 2 2 2 1 Reactive mitochondrial oxygen species modulator 1 TssN PF17555.2 AAL62520.1 - 0.12 11.7 1.4 0.36 10.2 0.1 1.9 2 0 0 2 2 2 0 Type VI secretion system, TssN EMP70 PF02990.16 AAL62520.1 - 0.22 10.2 1.2 0.23 10.1 1.2 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 TraL PF07178.11 AAL62520.1 - 5.6 7.5 8.8 2.8 8.5 2.2 2.4 1 1 1 2 2 2 0 TraL protein Phage_holin_2_1 PF04971.12 AAL62520.1 - 6.4 6.9 13.1 7.9 6.6 1.8 3.3 2 1 1 3 3 3 0 Bacteriophage P21 holin S Glyco_trans_2_3 PF13632.6 AAL62521.1 - 2.5e-17 63.4 2.2 3.4e-17 63.0 2.2 1.2 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 AAL62521.1 - 2.6e-09 37.3 0.9 1e-08 35.4 0.9 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 AAL62521.1 - 1.2e-05 24.9 0.0 1.6e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 HEPN PF05168.14 AAL62522.1 - 4.2e-35 120.4 1.0 4.9e-35 120.2 1.0 1.0 1 0 0 1 1 1 1 HEPN domain HEPN_AbiV PF18728.1 AAL62522.1 - 0.044 13.9 3.8 0.047 13.8 2.0 1.8 2 0 0 2 2 2 0 AbiV REV1_C PF16727.5 AAL62522.1 - 0.073 13.5 0.2 0.22 11.9 0.1 1.8 2 0 0 2 2 2 0 DNA repair protein REV1 C-terminal domain DUF4398 PF14346.6 AAL62522.1 - 8.5 7.1 10.8 9.2 7.0 6.5 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4398) NTP_transf_2 PF01909.23 AAL62523.1 - 7.9e-10 38.9 0.0 9.5e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 AAL62523.1 - 2.8e-07 30.5 0.0 3.9e-07 30.1 0.0 1.4 1 1 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase Glycos_trans_3N PF02885.17 AAL62523.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain Serpin PF00079.20 AAL62526.1 - 2.9e-68 230.9 0.0 6.2e-68 229.8 0.0 1.5 1 1 0 1 1 1 1 Serpin (serine protease inhibitor) FliS_cochap PF16522.5 AAL62528.1 - 0.01 15.8 0.4 0.015 15.2 0.2 1.4 1 1 0 1 1 1 0 Flagellar FLiS export co-chaperone, HP1076 Metallophos PF00149.28 AAL62529.1 - 1.3e-12 48.6 1.6 2.3e-12 47.8 1.6 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AAL62529.1 - 0.00068 19.9 0.0 0.0031 17.7 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MHYT PF03707.16 AAL62529.1 - 3.2 8.0 7.0 0.63 10.3 2.4 2.2 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat Pex14_N PF04695.13 AAL62529.1 - 5.6 7.6 13.1 10 6.7 13.1 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MotA_ExbB PF01618.16 AAL62530.1 - 0.063 13.0 1.6 0.069 12.9 1.6 1.1 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family PsaM PF07465.13 AAL62530.1 - 0.14 11.9 5.8 0.26 11.1 5.8 1.5 1 0 0 1 1 1 0 Photosystem I protein M (PsaM) Gram_pos_anchor PF00746.21 AAL62530.1 - 0.23 11.4 3.2 0.33 10.9 3.2 1.3 1 0 0 1 1 1 0 LPXTG cell wall anchor motif VirB8 PF04335.13 AAL62530.1 - 0.29 10.9 2.7 0.29 10.9 2.7 1.0 1 0 0 1 1 1 0 VirB8 protein ABC_transp_aux PF09822.9 AAL62531.1 - 5.1e-05 22.9 0.0 7.4e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 ABC-type uncharacterized transport system PP2C_2 PF13672.6 AAL62531.1 - 0.011 15.3 0.2 0.45 10.1 0.0 2.3 2 0 0 2 2 2 0 Protein phosphatase 2C Baculo_PEP_C PF04513.12 AAL62531.1 - 0.013 15.5 0.1 0.022 14.8 0.1 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 AAL62531.1 - 0.075 13.1 0.3 0.14 12.2 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) SBP_bac_1 PF01547.25 AAL62532.1 - 1.4e-16 61.3 7.6 1.4e-16 61.3 7.6 2.0 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 AAL62532.1 - 1.5e-16 61.0 3.2 1.5e-16 61.0 3.2 2.0 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AAL62532.1 - 4.7e-16 58.9 0.3 1.1e-15 57.8 0.3 1.5 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 AAL62532.1 - 0.00018 21.3 0.7 0.00018 21.3 0.7 2.3 3 0 0 3 3 3 1 Bacterial extracellular solute-binding protein SBP_bac_3 PF00497.20 AAL62532.1 - 0.019 14.4 0.2 2.6 7.4 0.0 2.6 3 0 0 3 3 3 0 Bacterial extracellular solute-binding proteins, family 3 BPD_transp_1 PF00528.22 AAL62533.1 - 9.6e-25 87.4 27.1 5.6e-14 52.3 7.8 4.0 2 2 1 4 4 4 2 Binding-protein-dependent transport system inner membrane component Tmemb_170 PF10190.9 AAL62533.1 - 0.00083 19.7 0.2 0.00083 19.7 0.2 4.1 4 0 0 4 4 4 1 Putative transmembrane protein 170 SNARE_assoc PF09335.11 AAL62533.1 - 0.0015 19.0 2.5 0.0015 19.0 2.5 5.2 5 1 0 5 5 5 1 SNARE associated Golgi protein Myelin_PLP PF01275.19 AAL62533.1 - 1 9.2 4.3 0.65 9.8 1.6 1.9 2 0 0 2 2 2 0 Myelin proteolipid protein (PLP or lipophilin) ABC_tran PF00005.27 AAL62534.1 - 5.6e-36 124.1 0.0 8.1e-36 123.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAL62534.1 - 1.1e-09 38.5 0.3 2.2e-05 24.4 0.1 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system TOBE_2 PF08402.10 AAL62534.1 - 1.9e-08 34.3 5.5 1.4e-07 31.6 0.1 3.7 3 2 1 4 4 3 1 TOBE domain AAA_16 PF13191.6 AAL62534.1 - 0.00042 20.7 0.5 0.00097 19.6 0.5 1.7 1 1 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 AAL62534.1 - 0.0009 19.2 0.0 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea SMC_N PF02463.19 AAL62534.1 - 0.0012 18.4 0.0 0.0098 15.4 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AAL62534.1 - 0.0013 19.0 1.6 0.0075 16.5 1.2 2.2 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 AAL62534.1 - 0.0072 16.8 1.5 0.029 14.8 0.4 2.4 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) TOBE PF03459.17 AAL62534.1 - 0.01 16.1 2.1 2.2 8.7 0.0 3.5 2 1 0 2 2 2 1 TOBE domain ABC_ATPase PF09818.9 AAL62534.1 - 0.01 14.6 0.4 0.26 10.1 0.1 2.6 2 1 0 2 2 2 0 Predicted ATPase of the ABC class CysA_C_terminal PF17850.1 AAL62534.1 - 0.015 15.8 2.8 0.14 12.7 1.6 2.7 2 0 0 2 2 2 0 CysA C-terminal regulatory domain RsgA_GTPase PF03193.16 AAL62534.1 - 0.029 14.3 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Rad17 PF03215.15 AAL62534.1 - 0.035 14.0 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain DUF2236 PF09995.9 AAL62534.1 - 0.038 14.2 2.6 0.11 12.7 0.7 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2236) NACHT PF05729.12 AAL62534.1 - 0.048 13.6 0.0 0.086 12.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 AAL62534.1 - 0.057 13.6 1.1 0.41 10.8 1.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AAL62534.1 - 0.062 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AAL62534.1 - 0.069 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.22 AAL62534.1 - 0.082 12.1 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ATPase PF06745.13 AAL62534.1 - 0.085 12.2 0.1 7.5 5.8 0.0 2.2 2 0 0 2 2 2 0 KaiC AAA_14 PF13173.6 AAL62534.1 - 0.094 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 AAL62534.1 - 0.16 11.3 0.0 0.35 10.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 AAL62534.1 - 0.21 12.1 0.0 0.55 10.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain Rop PF01815.16 AAL62534.1 - 0.22 11.4 0.0 0.42 10.5 0.0 1.4 1 0 0 1 1 1 0 Rop protein GTP_EFTU PF00009.27 AAL62535.1 - 3.4e-25 88.7 1.3 5.5e-24 84.8 1.3 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.11 AAL62535.1 - 1.4e-18 66.9 0.4 2.7e-18 66.0 0.4 1.5 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.25 AAL62535.1 - 4.9e-10 39.6 0.3 1.2e-09 38.4 0.3 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 AAL62535.1 - 0.00011 22.1 0.1 0.0002 21.3 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1_Xtn PF16897.5 AAL62535.1 - 0.0073 16.3 0.1 0.016 15.2 0.1 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain PduV-EutP PF10662.9 AAL62535.1 - 0.042 13.6 1.2 0.13 12.0 0.1 2.3 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF4235 PF14019.6 AAL62535.1 - 0.17 12.0 4.4 1.4 9.1 2.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4235) HD_6 PF18019.1 AAL62538.1 - 2.8e-06 27.6 0.0 3.9e-06 27.1 0.0 1.3 1 1 0 1 1 1 1 HD domain HD PF01966.22 AAL62538.1 - 8.8e-06 25.9 0.9 0.00057 20.1 0.9 2.8 1 1 0 1 1 1 1 HD domain Helicase_C PF00271.31 AAL62539.1 - 2.5e-10 40.7 0.1 1.3e-09 38.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 AAL62539.1 - 3.2e-08 33.6 0.0 0.0024 17.7 0.0 2.7 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 AAL62539.1 - 0.00054 20.0 0.0 0.0018 18.3 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 AAL62539.1 - 0.0029 17.1 0.0 0.011 15.2 0.0 1.9 2 0 0 2 2 2 1 PhoH-like protein IstB_IS21 PF01695.17 AAL62539.1 - 0.043 13.6 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein Rtt106_N PF18215.1 AAL62539.1 - 0.072 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Histone chaperone Rtt106 N-terminal domain GDNF PF02351.16 AAL62540.1 - 0.0093 16.9 0.2 0.012 16.6 0.2 1.2 1 0 0 1 1 1 1 GDNF/GAS1 domain CRISPR_Cas6 PF10040.9 AAL62543.1 - 4.2e-14 52.9 0.1 1.9e-13 50.8 0.1 1.9 2 0 0 2 2 2 1 CRISPR-associated endoribonuclease Cas6 Cas_Cas4 PF01930.17 AAL62546.1 - 1.1e-16 61.4 0.0 1.3e-16 61.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF83 PDDEXK_1 PF12705.7 AAL62546.1 - 0.00023 21.2 0.0 0.00024 21.1 0.0 1.2 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily CRISPR_Cas2 PF09827.9 AAL62547.1 - 1.5e-11 44.3 0.0 1.6e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 CRISPR associated protein Cas2 HNH_repeat PF18780.1 AAL62547.1 - 0.56 10.1 2.8 0.77 9.6 0.2 2.5 2 0 0 2 2 2 0 Homing endonuclease repeat Cas_Cas1 PF01867.16 AAL62548.1 - 4.6e-61 206.4 0.0 5.5e-61 206.2 0.0 1.0 1 0 0 1 1 1 1 CRISPR associated protein Cas1 Csa1 PF06023.12 AAL62549.1 - 2.6e-106 355.2 0.0 3.2e-106 355.0 0.0 1.0 1 0 0 1 1 1 1 CRISPR-associated exonuclease Csa1 CD225 PF04505.12 AAL62550.1 - 0.013 15.6 0.6 0.018 15.2 0.6 1.4 1 1 0 1 1 1 0 Interferon-induced transmembrane protein DUF2177 PF09945.9 AAL62552.1 - 0.023 14.8 5.0 0.031 14.4 5.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2177) DUF1304 PF06993.12 AAL62552.1 - 0.093 12.7 4.4 0.26 11.3 4.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1304) 7TMR-DISM_7TM PF07695.11 AAL62552.1 - 0.48 10.3 12.0 0.6 10.0 11.8 1.3 1 1 0 1 1 1 0 7TM diverse intracellular signalling Ion_trans_2 PF07885.16 AAL62552.1 - 0.73 9.8 7.0 1.8 8.6 7.0 1.8 1 1 0 1 1 1 0 Ion channel MerC PF03203.14 AAL62552.1 - 4.8 7.7 10.6 7.5 7.0 8.3 1.9 1 1 1 2 2 2 0 MerC mercury resistance protein DUF2201 PF09967.9 AAL62553.1 - 4.6e-14 52.6 0.0 9.8e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 VWA-like domain (DUF2201) DUF2201_N PF13203.6 AAL62553.1 - 2.4e-13 50.3 0.0 3.4e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Putative metallopeptidase domain VWA_CoxE PF05762.14 AAL62553.1 - 9.6e-08 31.7 0.0 2.5e-07 30.3 0.0 1.5 1 1 0 1 1 1 1 VWA domain containing CoxE-like protein VWA PF00092.28 AAL62553.1 - 0.00011 22.5 0.0 0.00019 21.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 AAL62553.1 - 0.0002 22.0 0.0 0.00043 20.9 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain AAA_5 PF07728.14 AAL62555.1 - 0.00019 21.4 0.0 0.019 15.0 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA PF00004.29 AAL62555.1 - 0.0032 17.9 0.0 0.012 16.1 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AAL62555.1 - 0.0053 17.2 0.0 0.045 14.1 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.6 AAL62555.1 - 0.016 15.5 0.0 0.41 11.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 AAL62555.1 - 0.033 14.0 0.0 0.63 9.8 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 AAL62555.1 - 0.058 13.7 0.0 0.6 10.4 0.0 2.4 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 AAL62555.1 - 0.18 11.1 0.0 9.5 5.5 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PaREP1 PF05942.11 AAL62557.1 - 7.8e-32 109.6 0.3 7.8e-32 109.6 0.3 1.5 2 0 0 2 2 2 1 Archaeal PaREP1/PaREP8 family AAA_21 PF13304.6 AAL62559.1 - 4.9e-19 69.3 0.0 2.9e-09 37.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AAL62559.1 - 1.9e-14 54.2 0.0 8e-09 35.7 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 AAL62559.1 - 2.6e-05 23.8 0.0 4.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_tran PF00005.27 AAL62559.1 - 3.7e-05 24.3 0.0 0.0001 22.8 0.0 1.9 2 0 0 2 2 2 1 ABC transporter DUF2813 PF11398.8 AAL62559.1 - 3.7e-05 23.1 0.0 0.00081 18.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2813) AAA_23 PF13476.6 AAL62559.1 - 0.00013 22.6 0.0 0.00021 21.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAL62559.1 - 0.00025 20.7 0.0 0.00082 19.1 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AAL62559.1 - 0.001 19.5 0.0 0.0017 18.7 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 AAL62559.1 - 0.0015 17.9 0.1 0.91 8.8 0.0 2.6 2 1 0 2 2 2 2 FtsK/SpoIIIE family AAA_27 PF13514.6 AAL62559.1 - 0.0026 17.4 0.0 0.004 16.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AAL62559.1 - 0.015 15.6 0.0 0.032 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 AAL62559.1 - 0.019 15.0 0.0 0.033 14.2 0.0 1.3 1 0 0 1 1 1 0 Dynamin family NACHT PF05729.12 AAL62559.1 - 0.056 13.4 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 AAL62559.1 - 0.073 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 AAL62559.1 - 0.13 12.3 0.0 14 5.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 AAL62559.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase RNA12 PF10443.9 AAL62559.1 - 0.14 10.8 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 RNA12 protein MMR_HSR1 PF01926.23 AAL62559.1 - 0.17 11.9 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase MraZ PF02381.18 AAL62560.1 - 0.063 13.3 0.0 0.08 12.9 0.0 1.2 1 0 0 1 1 1 0 MraZ protein, putative antitoxin-like MazE_antitoxin PF04014.18 AAL62560.1 - 0.11 12.5 0.6 0.26 11.3 0.6 1.6 1 1 0 1 1 1 0 Antidote-toxin recognition MazE, bacterial antitoxin PIN PF01850.21 AAL62561.1 - 1.4e-12 48.2 0.0 1.8e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 PIN domain DUF2684 PF10885.8 AAL62561.1 - 0.046 13.9 0.0 0.075 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2684) AAA_21 PF13304.6 AAL62562.1 - 7e-11 42.5 0.3 0.00032 20.6 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AAL62562.1 - 4.2e-08 33.3 0.0 5.7e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 AAL62562.1 - 4.7e-05 24.0 0.0 5.8e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAL62562.1 - 0.00041 20.0 0.0 0.00085 19.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 AAL62562.1 - 0.00082 18.9 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_tran PF00005.27 AAL62562.1 - 0.0025 18.3 0.0 0.0075 16.8 0.0 1.9 1 1 0 1 1 1 1 ABC transporter DUF2813 PF11398.8 AAL62562.1 - 0.0091 15.3 0.3 0.061 12.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2813) AAA_PrkA PF08298.11 AAL62562.1 - 0.029 13.3 0.0 0.04 12.8 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain DUF815 PF05673.13 AAL62562.1 - 0.052 12.7 0.0 0.073 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 AAL62562.1 - 0.056 13.2 0.0 0.58 9.9 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_27 PF13514.6 AAL62562.1 - 0.12 12.0 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 AAL62562.1 - 0.13 11.7 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 AAL62562.1 - 0.16 11.7 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain PPL4 PF18188.1 AAL62563.1 - 0.013 15.4 0.6 0.026 14.5 0.5 1.5 2 0 0 2 2 2 0 Prim-pol 4 PIN PF01850.21 AAL62564.1 - 6.7e-07 29.9 3.6 6.3e-05 23.5 3.6 2.9 1 1 0 1 1 1 1 PIN domain DUF5615 PF18480.1 AAL62564.1 - 0.013 15.3 0.0 0.26 11.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5615) Csm1_B PF18211.1 AAL62566.1 - 8.2e-07 28.8 0.0 3e-06 27.0 0.0 2.0 1 0 0 1 1 1 1 Csm1 subunit domain B HD PF01966.22 AAL62566.1 - 2.5e-06 27.7 0.5 1.9e-05 24.8 0.1 2.4 2 0 0 2 2 2 1 HD domain mRNA_decap_C PF16741.5 AAL62566.1 - 0.15 11.4 0.0 0.32 10.3 0.0 1.5 1 0 0 1 1 1 0 mRNA-decapping enzyme C-terminus RAMPs PF03787.15 AAL62567.1 - 0.033 14.2 0.1 0.055 13.5 0.1 1.6 1 1 0 1 1 1 0 RAMP superfamily RAMPs PF03787.15 AAL62569.1 - 1.7e-09 38.1 0.0 2.8e-09 37.3 0.0 1.4 1 1 0 1 1 1 1 RAMP superfamily Csm2_III-A PF03750.13 AAL62570.1 - 0.0091 16.8 0.0 0.013 16.3 0.0 1.3 1 0 0 1 1 1 1 Csm2 Type III-A AAA_15 PF13175.6 AAL62571.1 - 1.6e-08 34.6 0.0 0.00066 19.5 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 AAL62571.1 - 8.5e-06 25.8 0.0 0.023 14.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AAL62571.1 - 0.032 14.7 0.0 0.074 13.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AAL62571.1 - 0.041 14.4 0.0 0.066 13.7 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 AAL62571.1 - 0.058 13.8 0.0 0.18 12.2 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 AAL62571.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain CAMP_factor PF07373.11 AAL62571.1 - 0.15 11.6 0.1 0.3 10.6 0.1 1.4 1 0 0 1 1 1 0 CAMP factor (Cfa) Cas_DxTHG PF09455.10 AAL62572.1 - 5.1e-17 62.5 0.0 4.7e-16 59.3 0.0 2.0 1 1 0 1 1 1 1 CRISPR-associated (Cas) DxTHG family Sin3a_C PF16879.5 AAL62572.1 - 0.0011 18.7 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 C-terminal domain of Sin3a protein HTH_Tnp_Tc3_2 PF01498.18 AAL62572.1 - 0.077 13.3 0.1 0.84 9.9 0.0 2.3 2 0 0 2 2 2 0 Transposase UTRA PF07702.13 AAL62573.1 - 0.04 13.8 0.0 0.045 13.6 0.0 1.2 1 0 0 1 1 1 0 UTRA domain Cas_DxTHG PF09455.10 AAL62574.1 - 3.4e-12 46.6 0.0 1.3e-08 34.8 0.0 2.1 2 0 0 2 2 2 2 CRISPR-associated (Cas) DxTHG family Cas_Cmr3 PF09700.10 AAL62574.1 - 0.081 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cmr3) Cas_DxTHG PF09455.10 AAL62576.1 - 0.00052 19.7 0.0 0.0014 18.3 0.0 1.7 1 1 0 1 1 1 1 CRISPR-associated (Cas) DxTHG family NurA PF09376.10 AAL62577.1 - 7.5e-17 61.8 0.0 9.3e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 NurA domain Cas_APE2256 PF09651.10 AAL62578.1 - 0.00077 19.4 0.0 0.00087 19.2 0.0 1.1 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_APE2256) Adenine_deam_C PF13382.6 AAL62578.1 - 0.0053 16.1 0.0 0.0059 16.0 0.0 1.1 1 0 0 1 1 1 1 Adenine deaminase C-terminal domain Cas_APE2256 PF09651.10 AAL62579.1 - 5e-37 126.8 0.0 6.2e-37 126.5 0.0 1.1 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_APE2256) Frag1 PF10277.9 AAL62579.1 - 0.042 13.4 0.0 0.057 13.0 0.0 1.1 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family DUF853 PF05872.12 AAL62580.1 - 2.5e-12 46.2 0.2 8.4e-06 24.6 0.1 2.2 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF853) DUF87 PF01935.17 AAL62580.1 - 1.8e-11 44.6 0.0 3.7e-11 43.6 0.0 1.6 1 1 0 1 1 1 1 Helicase HerA, central domain AAA_22 PF13401.6 AAL62580.1 - 3.1e-07 30.7 0.0 0.013 15.7 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA PF00004.29 AAL62580.1 - 1.2e-06 29.0 0.3 0.052 14.0 0.1 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 AAL62580.1 - 1.9e-06 27.4 0.0 0.00064 19.2 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_16 PF13191.6 AAL62580.1 - 7.7e-06 26.4 0.9 0.00018 21.9 0.9 2.3 1 1 0 1 1 1 1 AAA ATPase domain TrwB_AAD_bind PF10412.9 AAL62580.1 - 1.2e-05 24.4 0.0 7.8e-05 21.8 0.0 2.0 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_10 PF12846.7 AAL62580.1 - 4.8e-05 22.4 0.1 0.17 10.8 0.0 2.2 2 0 0 2 2 2 2 AAA-like domain AAA_25 PF13481.6 AAL62580.1 - 0.00027 20.5 0.1 0.32 10.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.9 AAL62580.1 - 0.00048 19.5 0.2 0.29 10.3 0.0 2.1 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 AAL62580.1 - 0.0018 17.8 0.0 0.0032 17.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region NACHT PF05729.12 AAL62580.1 - 0.0046 16.9 0.1 0.0092 15.9 0.1 1.5 1 0 0 1 1 1 1 NACHT domain Zot PF05707.12 AAL62580.1 - 0.0048 16.6 0.2 0.055 13.1 0.0 2.6 3 0 0 3 3 3 1 Zonular occludens toxin (Zot) ResIII PF04851.15 AAL62580.1 - 0.0059 16.6 0.0 0.053 13.5 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Mg_chelatase PF01078.21 AAL62580.1 - 0.024 14.0 0.0 0.048 13.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 AAL62580.1 - 0.042 13.8 0.2 0.24 11.4 0.1 2.2 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 AAL62580.1 - 0.045 14.3 0.0 0.1 13.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 AAL62580.1 - 0.045 13.5 0.1 3.4 7.4 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase T2SSE PF00437.20 AAL62580.1 - 0.049 12.7 0.0 0.12 11.4 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.6 AAL62580.1 - 0.08 13.1 0.1 0.33 11.1 0.1 2.1 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 AAL62580.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 AAL62580.1 - 0.11 11.8 0.2 0.22 10.8 0.2 1.4 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 AAL62580.1 - 0.11 13.0 0.1 0.31 11.5 0.1 1.7 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 AAL62580.1 - 0.14 12.4 0.6 0.31 11.3 0.6 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AAL62580.1 - 0.15 11.8 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 AAL62580.1 - 0.17 11.6 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain NB-ARC PF00931.22 AAL62580.1 - 0.18 11.0 0.0 0.3 10.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 AAL62580.1 - 0.19 12.3 0.1 0.51 10.9 0.1 1.7 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 AAL62580.1 - 0.25 10.8 0.0 0.43 10.0 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Cas6_N PF17952.1 AAL62581.1 - 1.2e-10 41.7 0.0 1.5e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Cas6 N-terminal domain CRISPR_Cas6 PF10040.9 AAL62582.1 - 5.1e-09 36.7 0.0 5.5e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 CRISPR-associated endoribonuclease Cas6 Cas_Cas6 PF01881.16 AAL62582.1 - 0.04 14.5 0.0 0.046 14.3 0.0 1.2 1 0 0 1 1 1 0 CRISPR associated protein Cas6 Cas6b_C PF17262.2 AAL62582.1 - 0.043 13.9 0.2 0.086 13.0 0.1 1.5 1 1 0 1 1 1 0 Cas6b C-terminal domain RAMPs PF03787.15 AAL62582.1 - 0.055 13.5 0.1 0.064 13.3 0.1 1.1 1 0 0 1 1 1 0 RAMP superfamily DUF5558 PF17713.1 AAL62582.1 - 0.18 12.2 0.0 0.21 12.0 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5558) DUF4781 PF16013.5 AAL62583.1 - 0.19 10.5 1.0 0.19 10.5 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) DUF5518 PF17647.1 AAL62585.1 - 1.9e-13 50.6 30.8 2.2e-13 50.4 30.8 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5518) Gly-zipper_Omp PF13488.6 AAL62585.1 - 0.095 12.7 0.2 0.095 12.7 0.2 3.4 2 1 0 3 3 3 0 Glycine zipper Herpes_UL56 PF04534.12 AAL62588.1 - 0.03 13.8 0.6 0.031 13.8 0.6 1.1 1 0 0 1 1 1 0 Herpesvirus UL56 protein DUF1664 PF07889.12 AAL62590.1 - 1.7e-06 28.1 0.3 0.00035 20.6 0.2 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) PspA_IM30 PF04012.12 AAL62590.1 - 3e-06 27.0 0.0 0.0078 15.8 0.1 2.1 1 1 1 2 2 2 2 PspA/IM30 family SlyX PF04102.12 AAL62590.1 - 3.4e-06 27.6 0.7 0.00027 21.5 0.1 2.2 1 1 1 2 2 2 2 SlyX BLOC1_2 PF10046.9 AAL62590.1 - 8.1e-06 26.0 0.0 0.12 12.7 0.0 2.2 1 1 1 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlaC_arch PF05377.11 AAL62590.1 - 1.4e-05 25.4 2.1 0.017 15.5 1.9 3.2 1 1 2 3 3 3 2 Flagella accessory protein C (FlaC) DUF2730 PF10805.8 AAL62590.1 - 2.7e-05 24.2 0.4 0.00019 21.5 0.3 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF2730) Baculo_PEP_C PF04513.12 AAL62590.1 - 4.5e-05 23.5 0.1 0.0021 18.1 0.2 2.0 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 AAL62590.1 - 4.5e-05 23.4 0.4 6.2e-05 22.9 0.4 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain HSBP1 PF06825.12 AAL62590.1 - 5e-05 23.1 1.1 0.17 11.8 0.1 3.9 1 1 3 4 4 4 1 Heat shock factor binding protein 1 TMF_TATA_bd PF12325.8 AAL62590.1 - 5e-05 23.5 0.5 7e-05 23.0 0.5 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding Laminin_II PF06009.12 AAL62590.1 - 7.6e-05 22.7 0.4 0.00016 21.7 0.4 1.5 1 1 0 1 1 1 1 Laminin Domain II CLZ PF16526.5 AAL62590.1 - 8.8e-05 22.8 1.4 0.0055 17.0 1.0 2.6 1 1 2 3 3 3 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TMF_DNA_bd PF12329.8 AAL62590.1 - 9e-05 22.4 1.0 0.00018 21.4 1.0 1.6 1 1 0 1 1 1 1 TATA element modulatory factor 1 DNA binding DUF948 PF06103.11 AAL62590.1 - 0.00011 22.4 0.4 0.00055 20.1 0.3 2.2 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF948) Spc7 PF08317.11 AAL62590.1 - 0.00028 19.9 0.0 0.00036 19.5 0.0 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein bZIP_1 PF00170.21 AAL62590.1 - 0.00031 20.8 2.7 0.018 15.1 0.4 2.8 1 1 2 3 3 3 2 bZIP transcription factor DUF3450 PF11932.8 AAL62590.1 - 0.00035 20.0 0.0 0.00037 19.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Myosin_tail_1 PF01576.19 AAL62590.1 - 0.00039 18.4 0.2 0.00045 18.2 0.2 1.0 1 0 0 1 1 1 1 Myosin tail ABC_tran_CTD PF16326.5 AAL62590.1 - 0.00047 20.4 0.0 0.001 19.3 0.0 1.6 2 0 0 2 2 1 1 ABC transporter C-terminal domain TolA_bind_tri PF16331.5 AAL62590.1 - 0.00047 20.2 2.0 0.031 14.4 0.7 3.0 1 1 1 2 2 2 2 TolA binding protein trimerisation ATG16 PF08614.11 AAL62590.1 - 0.00051 20.3 0.6 0.00063 20.0 0.6 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) ADIP PF11559.8 AAL62590.1 - 0.00065 19.8 0.1 0.0015 18.6 0.1 1.6 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding PspB PF06667.12 AAL62590.1 - 0.0013 18.7 0.2 0.042 13.9 0.1 2.5 1 1 1 2 2 2 1 Phage shock protein B HemX PF04375.14 AAL62590.1 - 0.0014 18.0 0.0 0.0016 17.8 0.0 1.1 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase DUF16 PF01519.16 AAL62590.1 - 0.0017 18.8 0.1 0.0073 16.8 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function DUF16 CENP-F_leu_zip PF10473.9 AAL62590.1 - 0.0017 18.4 0.9 0.0027 17.7 0.9 1.4 1 1 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4988 PF16378.5 AAL62590.1 - 0.0019 17.9 1.5 0.031 14.0 0.5 2.4 1 1 1 2 2 2 1 Domain of unknown function DUF4618 PF15397.6 AAL62590.1 - 0.0021 17.5 0.1 0.012 15.1 0.0 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4618) Fib_alpha PF08702.10 AAL62590.1 - 0.0025 18.0 0.2 0.024 14.8 0.3 1.8 1 1 0 1 1 1 1 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 AAL62590.1 - 0.0029 18.0 0.1 0.4 11.2 0.3 2.4 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein DASH_Dam1 PF08653.10 AAL62590.1 - 0.0032 17.2 0.3 1.3 8.9 0.5 2.4 1 1 1 2 2 2 1 DASH complex subunit Dam1 DUF4164 PF13747.6 AAL62590.1 - 0.0039 17.4 1.5 0.0039 17.4 1.5 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4164) EzrA PF06160.12 AAL62590.1 - 0.0043 15.3 0.0 0.0055 15.0 0.0 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Prefoldin_2 PF01920.20 AAL62590.1 - 0.0051 16.7 0.1 0.067 13.1 0.1 2.2 1 1 0 2 2 2 1 Prefoldin subunit TACC_C PF05010.14 AAL62590.1 - 0.0053 16.6 0.0 0.0068 16.2 0.0 1.2 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Flagellin_C PF00700.21 AAL62590.1 - 0.0064 16.8 0.2 0.023 15.0 0.2 2.0 1 1 0 1 1 1 1 Bacterial flagellin C-terminal helical region GrpE PF01025.19 AAL62590.1 - 0.0065 16.1 0.4 0.05 13.3 0.4 1.9 1 1 1 2 2 2 1 GrpE Prominin PF05478.11 AAL62590.1 - 0.007 14.4 0.2 0.0085 14.1 0.2 1.1 1 0 0 1 1 1 1 Prominin DUF5082 PF16888.5 AAL62590.1 - 0.007 16.6 0.2 0.11 12.8 0.2 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF5082) AAA_13 PF13166.6 AAL62590.1 - 0.0074 15.0 0.0 0.0089 14.7 0.0 1.0 1 0 0 1 1 1 1 AAA domain ZapB PF06005.12 AAL62590.1 - 0.0077 16.7 0.2 0.014 15.9 0.2 1.5 1 0 0 1 1 1 1 Cell division protein ZapB Atg14 PF10186.9 AAL62590.1 - 0.008 15.3 0.0 0.01 15.0 0.0 1.0 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 XhlA PF10779.9 AAL62590.1 - 0.0097 16.1 3.0 0.033 14.4 1.8 2.3 1 1 1 2 2 2 1 Haemolysin XhlA Snapin_Pallidin PF14712.6 AAL62590.1 - 0.0097 16.3 1.0 1.4 9.3 0.7 2.5 1 1 1 2 2 2 1 Snapin/Pallidin STAT_alpha PF01017.20 AAL62590.1 - 0.012 15.5 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 STAT protein, all-alpha domain COG5 PF10392.9 AAL62590.1 - 0.013 15.7 0.1 0.42 10.8 0.1 2.1 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Fzo_mitofusin PF04799.13 AAL62590.1 - 0.013 15.0 0.2 0.24 10.9 0.3 2.3 1 1 1 2 2 2 0 fzo-like conserved region DUF2046 PF09755.9 AAL62590.1 - 0.014 14.7 0.3 0.017 14.3 0.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) DHR10 PF18595.1 AAL62590.1 - 0.018 15.1 0.5 0.065 13.3 0.4 1.8 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain HalX PF08663.10 AAL62590.1 - 0.018 15.4 1.9 7.2 7.0 0.1 3.5 1 1 2 3 3 3 0 HalX domain JIP_LZII PF16471.5 AAL62590.1 - 0.018 15.2 3.2 0.027 14.7 1.2 2.1 1 1 2 3 3 2 0 JNK-interacting protein leucine zipper II KxDL PF10241.9 AAL62590.1 - 0.02 15.1 0.2 0.062 13.6 0.1 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein TelA PF05816.11 AAL62590.1 - 0.021 13.9 0.1 0.046 12.8 0.0 1.5 1 1 1 2 2 2 0 Toxic anion resistance protein (TelA) Tropomyosin PF00261.20 AAL62590.1 - 0.021 14.2 0.6 0.033 13.5 0.6 1.4 1 0 0 1 1 1 0 Tropomyosin Cortex-I_coil PF09304.10 AAL62590.1 - 0.024 14.9 1.3 0.032 14.5 1.3 1.2 1 0 0 1 1 1 0 Cortexillin I, coiled coil BRE1 PF08647.11 AAL62590.1 - 0.024 14.7 0.1 0.035 14.2 0.1 1.3 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase DivIC PF04977.15 AAL62590.1 - 0.024 14.4 0.8 0.61 9.9 0.5 2.4 1 1 1 2 2 2 0 Septum formation initiator DUF4795 PF16043.5 AAL62590.1 - 0.025 14.2 0.1 0.045 13.3 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) FapA PF03961.13 AAL62590.1 - 0.028 13.1 0.0 0.033 12.8 0.0 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A CdvA PF18822.1 AAL62590.1 - 0.028 14.2 0.5 0.64 9.9 0.4 2.3 1 1 1 2 2 2 0 CdvA-like coiled-coil domain Spectrin PF00435.21 AAL62590.1 - 0.029 14.8 0.0 0.046 14.2 0.0 1.3 1 0 0 1 1 1 0 Spectrin repeat DUF4472 PF14739.6 AAL62590.1 - 0.03 15.1 0.0 0.041 14.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) APG17 PF04108.12 AAL62590.1 - 0.03 13.4 0.1 0.081 12.0 0.1 1.4 1 1 0 1 1 1 0 Autophagy protein Apg17 TPR_MLP1_2 PF07926.12 AAL62590.1 - 0.031 14.3 0.2 0.13 12.4 0.3 1.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein IFT57 PF10498.9 AAL62590.1 - 0.032 13.2 0.0 0.038 13.0 0.0 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Exonuc_VII_L PF02601.15 AAL62590.1 - 0.032 13.8 0.0 0.037 13.6 0.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit PTRF_SDPR PF15237.6 AAL62590.1 - 0.032 13.9 0.2 0.045 13.4 0.2 1.2 1 0 0 1 1 1 0 PTRF/SDPR family CCDC154 PF15450.6 AAL62590.1 - 0.033 12.7 0.1 0.041 12.4 0.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 154 Nup54 PF13874.6 AAL62590.1 - 0.033 14.3 0.4 0.07 13.2 0.4 1.6 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 HrpB7 PF09486.10 AAL62590.1 - 0.037 14.4 0.6 0.73 10.2 0.2 2.0 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Occludin_ELL PF07303.13 AAL62590.1 - 0.038 14.7 0.0 0.11 13.3 0.0 1.7 1 1 0 1 1 1 0 Occludin homology domain Trimer_CC PF08954.11 AAL62590.1 - 0.041 13.4 2.2 0.74 9.4 0.0 3.1 2 1 1 3 3 3 0 Trimerisation motif DUF745 PF05335.13 AAL62590.1 - 0.041 13.6 0.0 0.052 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) MbeD_MobD PF04899.12 AAL62590.1 - 0.043 13.9 0.1 3 8.0 0.0 2.4 1 1 1 2 2 2 0 MbeD/MobD like DUF3552 PF12072.8 AAL62590.1 - 0.043 13.2 0.2 0.054 12.9 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) COG2 PF06148.11 AAL62590.1 - 0.044 13.9 0.9 2 8.5 0.3 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Not3 PF04065.15 AAL62590.1 - 0.046 13.1 0.0 0.057 12.9 0.0 1.1 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component HMMR_N PF15905.5 AAL62590.1 - 0.047 13.2 0.1 0.063 12.8 0.1 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Lebercilin PF15619.6 AAL62590.1 - 0.049 13.3 0.7 0.14 11.8 0.7 1.7 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease FPP PF05911.11 AAL62590.1 - 0.052 11.8 0.0 0.057 11.6 0.0 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil SHE3 PF17078.5 AAL62590.1 - 0.053 13.2 0.5 0.1 12.3 0.5 1.4 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 CALCOCO1 PF07888.11 AAL62590.1 - 0.053 12.4 0.4 0.069 12.0 0.4 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Tropomyosin_1 PF12718.7 AAL62590.1 - 0.054 13.6 0.4 0.088 13.0 0.4 1.5 1 1 0 1 1 1 0 Tropomyosin like Tektin PF03148.14 AAL62590.1 - 0.055 12.2 0.1 0.079 11.7 0.1 1.3 1 0 0 1 1 1 0 Tektin family Surfac_D-trimer PF09006.11 AAL62590.1 - 0.058 13.3 0.4 15 5.6 0.1 3.2 1 1 2 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation WXG100 PF06013.12 AAL62590.1 - 0.059 13.6 0.0 11 6.3 0.0 2.5 1 1 0 2 2 2 0 Proteins of 100 residues with WXG FH2 PF02181.23 AAL62590.1 - 0.062 12.4 0.0 0.075 12.1 0.0 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain RmuC PF02646.16 AAL62590.1 - 0.064 12.4 0.1 0.21 10.7 0.2 1.6 1 1 1 2 2 2 0 RmuC family YscO PF07321.12 AAL62590.1 - 0.071 13.1 1.0 2.6 8.0 0.5 2.1 1 1 1 2 2 2 0 Type III secretion protein YscO Nup88 PF10168.9 AAL62590.1 - 0.071 10.9 0.1 0.078 10.8 0.1 1.1 1 0 0 1 1 1 0 Nuclear pore component MscS_porin PF12795.7 AAL62590.1 - 0.075 12.6 0.0 0.16 11.5 0.0 1.4 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain Wtap PF17098.5 AAL62590.1 - 0.081 12.9 0.7 0.42 10.5 0.7 2.1 1 1 0 1 1 1 0 WTAP/Mum2p family DASH_Spc19 PF08287.11 AAL62590.1 - 0.081 12.8 1.0 0.78 9.6 0.4 2.0 1 1 1 2 2 2 0 Spc19 Fez1 PF06818.15 AAL62590.1 - 0.082 13.4 0.0 0.1 13.1 0.0 1.1 1 0 0 1 1 1 0 Fez1 HAUS-augmin3 PF14932.6 AAL62590.1 - 0.085 12.4 0.1 0.15 11.6 0.1 1.4 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 DLP_helical PF18709.1 AAL62590.1 - 0.095 11.9 0.1 0.11 11.7 0.1 1.2 1 0 0 1 1 1 0 Dynamin-like helical domain CENP-K PF11802.8 AAL62590.1 - 0.097 12.2 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Centromere-associated protein K DegS PF05384.11 AAL62590.1 - 0.097 12.2 1.7 0.15 11.5 0.9 1.6 1 1 0 1 1 1 0 Sensor protein DegS Macoilin PF09726.9 AAL62590.1 - 0.098 11.2 0.2 0.12 11.0 0.2 1.0 1 0 0 1 1 1 0 Macoilin family LPP PF04728.13 AAL62590.1 - 0.099 13.1 0.4 3.9 7.9 0.1 3.1 2 1 2 4 4 3 0 Lipoprotein leucine-zipper YabA PF06156.13 AAL62590.1 - 0.11 13.1 0.2 0.54 10.9 0.2 1.9 1 1 0 1 1 1 0 Initiation control protein YabA FliJ PF02050.16 AAL62590.1 - 0.12 12.6 0.0 0.77 10.0 0.0 1.9 1 1 1 2 2 2 0 Flagellar FliJ protein Hemagglutinin PF00509.18 AAL62590.1 - 0.12 10.8 0.1 0.14 10.6 0.1 1.3 1 0 0 1 1 1 0 Haemagglutinin Syntaxin-6_N PF09177.11 AAL62590.1 - 0.13 12.8 0.2 1.2 9.7 0.3 1.9 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Med9 PF07544.13 AAL62590.1 - 0.13 12.4 0.5 3.8 7.7 0.2 2.4 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Fmp27_WPPW PF10359.9 AAL62590.1 - 0.14 11.0 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Spc24 PF08286.11 AAL62590.1 - 0.15 12.3 0.7 0.39 11.0 0.7 1.7 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DUF724 PF05266.14 AAL62590.1 - 0.16 11.8 0.1 0.46 10.3 0.1 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF724) BRI3BP PF14965.6 AAL62590.1 - 0.29 10.6 2.1 2.9 7.4 1.0 2.6 1 1 1 2 2 2 0 Negative regulator of p53/TP53 DUF4349 PF14257.6 AAL62590.1 - 0.31 10.5 5.9 0.86 9.0 0.1 2.4 2 1 1 3 3 2 0 Domain of unknown function (DUF4349) CCDC-167 PF15188.6 AAL62590.1 - 1.1 9.7 5.2 0.54 10.6 1.0 2.4 2 1 1 3 3 2 0 Coiled-coil domain-containing protein 167 GGACT PF06094.12 AAL62592.1 - 7.1e-21 75.1 0.3 7.5e-21 75.0 0.3 1.0 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 AAL62592.1 - 0.053 13.9 0.0 0.081 13.3 0.0 1.3 1 0 0 1 1 1 0 AIG2-like family HTH_24 PF13412.6 AAL62593.1 - 2e-09 36.9 0.0 3.2e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 AAL62593.1 - 5.2e-08 32.7 0.4 9.2e-08 31.9 0.4 1.4 1 0 0 1 1 1 1 MarR family TrmB PF01978.19 AAL62593.1 - 7.4e-08 32.2 0.2 1.3e-07 31.4 0.2 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR PF01047.22 AAL62593.1 - 5.6e-07 29.4 0.0 9.6e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_IclR PF09339.10 AAL62593.1 - 2.5e-06 27.2 0.1 5.8e-06 26.0 0.1 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_20 PF12840.7 AAL62593.1 - 6e-06 26.2 0.3 1.6e-05 24.8 0.3 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_27 PF13463.6 AAL62593.1 - 1.1e-05 25.8 0.1 2e-05 25.0 0.1 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain GntR PF00392.21 AAL62593.1 - 2.3e-05 23.9 1.7 3.2e-05 23.5 0.3 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family Fe_dep_repress PF01325.19 AAL62593.1 - 8.3e-05 22.7 0.0 0.00016 21.8 0.0 1.5 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_Crp_2 PF13545.6 AAL62593.1 - 0.0011 18.9 0.1 0.0021 18.0 0.1 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain DUF2250 PF10007.9 AAL62593.1 - 0.0014 18.7 0.0 0.0023 18.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) RPA_C PF08784.11 AAL62593.1 - 0.0016 19.1 0.8 0.014 16.0 0.8 2.2 1 1 0 1 1 1 1 Replication protein A C terminal HTH_23 PF13384.6 AAL62593.1 - 0.0016 18.2 0.1 0.0031 17.3 0.1 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_AsnC-type PF13404.6 AAL62593.1 - 0.0042 16.9 0.0 0.0077 16.0 0.0 1.5 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_29 PF13551.6 AAL62593.1 - 0.0046 16.9 0.1 0.0094 16.0 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn helix Penicillinase_R PF03965.16 AAL62593.1 - 0.022 15.1 0.0 0.049 14.0 0.0 1.5 1 0 0 1 1 1 0 Penicillinase repressor HTH_28 PF13518.6 AAL62593.1 - 0.028 14.5 0.4 0.067 13.3 0.2 1.8 1 1 0 1 1 1 0 Helix-turn-helix domain TFIIE_alpha PF02002.17 AAL62593.1 - 0.065 13.1 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 TFIIE alpha subunit Sigma70_r4_2 PF08281.12 AAL62593.1 - 0.066 12.9 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 Pex14_N PF04695.13 AAL62593.1 - 0.1 13.2 12.4 0.3 11.8 12.9 1.5 2 0 0 2 2 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Rrf2 PF02082.20 AAL62593.1 - 0.1 12.9 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator Sigma70_r4 PF04545.16 AAL62593.1 - 0.11 12.1 1.0 0.24 11.0 1.0 1.6 1 1 0 1 1 1 0 Sigma-70, region 4 DUF4366 PF14283.6 AAL62593.1 - 0.14 12.2 2.6 0.23 11.5 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) PheRS_DBD1 PF18552.1 AAL62593.1 - 0.18 11.6 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 PheRS DNA binding domain 1 PerB PF06590.11 AAL62594.1 - 0.065 13.7 0.2 0.11 13.0 0.2 1.3 1 0 0 1 1 1 0 PerB protein WYL PF13280.6 AAL62594.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.6 2 0 0 2 2 2 0 WYL domain PIN PF01850.21 AAL62596.1 - 2.9e-14 53.6 2.4 3.6e-14 53.3 2.4 1.1 1 0 0 1 1 1 1 PIN domain PIN_2 PF10130.9 AAL62596.1 - 0.0022 18.3 0.4 0.0026 18.0 0.4 1.0 1 0 0 1 1 1 1 PIN domain Arg_decarb_HB PF17810.1 AAL62596.1 - 0.011 16.0 0.1 0.027 14.7 0.1 1.8 1 1 0 1 1 1 0 Arginine decarboxylase helical bundle domain CcdA PF07362.12 AAL62597.1 - 0.0007 20.0 0.9 0.001 19.5 0.9 1.3 1 0 0 1 1 1 1 Post-segregation antitoxin CcdA PVL_ORF50 PF07768.11 AAL62597.1 - 0.056 13.8 2.4 0.071 13.4 2.4 1.2 1 0 0 1 1 1 0 PVL ORF-50-like family PSK_trans_fac PF07704.11 AAL62597.1 - 0.085 13.6 6.0 0.13 13.1 6.0 1.3 1 1 0 1 1 1 0 Rv0623-like transcription factor AAA_31 PF13614.6 AAL62598.1 - 1e-12 48.3 0.0 1.9e-12 47.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 AAL62598.1 - 4.9e-09 36.3 0.0 8.1e-09 35.6 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 AAL62598.1 - 0.00081 18.7 0.0 0.0037 16.5 0.0 1.9 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.6 AAL62598.1 - 0.0013 18.3 0.9 0.0066 16.1 0.9 2.1 1 1 0 1 1 1 1 AAA domain SAM_DrpA PF18255.1 AAL62598.1 - 0.0018 18.5 0.0 0.0039 17.4 0.0 1.5 1 0 0 1 1 1 1 DNA processing protein A sterile alpha motif domain Ribosomal_L4 PF00573.22 AAL62598.1 - 0.096 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L4/L1 family ParA PF10609.9 AAL62598.1 - 0.19 11.2 0.1 0.87 9.0 0.1 1.8 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 AAL62598.1 - 0.2 11.1 0.0 0.84 9.1 0.0 1.9 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ DUF35_N PF12172.8 AAL62600.1 - 3.7e-06 26.7 2.1 0.00039 20.2 0.1 2.1 2 0 0 2 2 2 1 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-ribbon_3 PF13248.6 AAL62600.1 - 2.3e-05 23.6 1.5 0.1 12.0 0.1 2.2 2 0 0 2 2 2 2 zinc-ribbon domain DZR PF12773.7 AAL62600.1 - 2.5e-05 24.2 0.2 2.7e-05 24.1 0.2 1.1 1 0 0 1 1 1 1 Double zinc ribbon UPF0547 PF10571.9 AAL62600.1 - 3.1e-05 24.0 2.6 0.003 17.6 0.1 2.1 2 0 0 2 2 2 1 Uncharacterised protein family UPF0547 Nudix_N_2 PF14803.6 AAL62600.1 - 6.2e-05 22.8 1.7 9.2e-05 22.3 1.7 1.4 1 1 0 1 1 1 1 Nudix N-terminal Zn-ribbon_8 PF09723.10 AAL62600.1 - 0.00013 22.1 0.3 0.00018 21.6 0.3 1.3 1 0 0 1 1 1 1 Zinc ribbon domain YhfH PF14149.6 AAL62600.1 - 0.00022 21.1 0.1 0.3 11.1 0.0 2.1 2 0 0 2 2 2 2 YhfH-like protein zinc_ribbon_2 PF13240.6 AAL62600.1 - 0.00025 20.6 0.5 0.47 10.2 0.0 2.1 2 0 0 2 2 2 2 zinc-ribbon domain zf-NADH-PPase PF09297.11 AAL62600.1 - 0.00046 19.8 0.6 0.6 9.8 0.1 2.2 2 0 0 2 2 2 2 NADH pyrophosphatase zinc ribbon domain zf-TFIIB PF13453.6 AAL62600.1 - 0.00058 19.1 0.6 0.00071 18.9 0.6 1.2 1 0 0 1 1 1 1 Transcription factor zinc-finger Methyltransf_13 PF08421.11 AAL62600.1 - 0.00088 19.5 0.7 0.013 15.7 0.0 2.0 1 1 1 2 2 2 1 Putative zinc binding domain TF_Zn_Ribbon PF08271.12 AAL62600.1 - 0.0031 17.0 5.3 0.085 12.4 0.5 2.1 1 1 1 2 2 2 2 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.11 AAL62600.1 - 0.0049 16.8 0.8 0.008 16.1 0.8 1.4 1 1 0 1 1 1 1 Putative transposase DNA-binding domain zf-tcix PF14952.6 AAL62600.1 - 0.005 16.4 3.3 0.23 11.1 0.1 2.3 2 0 0 2 2 2 1 Putative treble-clef, zinc-finger, Zn-binding zf-FPG_IleRS PF06827.14 AAL62600.1 - 0.0056 16.5 0.8 0.18 11.7 0.1 2.1 2 0 0 2 2 2 1 Zinc finger found in FPG and IleRS zinc_ribbon_4 PF13717.6 AAL62600.1 - 0.0078 16.1 2.0 0.31 11.0 2.4 2.5 2 1 0 2 2 2 1 zinc-ribbon domain RNA_POL_M_15KD PF02150.16 AAL62600.1 - 0.0096 15.8 0.1 0.016 15.1 0.1 1.3 1 0 0 1 1 1 1 RNA polymerases M/15 Kd subunit zf-ISL3 PF14690.6 AAL62600.1 - 0.01 16.5 1.1 1.5 9.6 0.1 2.1 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-C2HC5 PF06221.13 AAL62600.1 - 0.011 15.7 0.3 0.014 15.3 0.3 1.3 1 1 0 1 1 1 0 Putative zinc finger motif, C2HC5-type zf-H2C2_2 PF13465.6 AAL62600.1 - 0.018 15.4 1.6 0.94 10.0 0.1 2.1 2 0 0 2 2 2 0 Zinc-finger double domain IBR PF01485.21 AAL62600.1 - 0.021 15.0 0.2 0.027 14.7 0.2 1.2 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain CpXC PF14353.6 AAL62600.1 - 0.022 14.8 1.4 0.41 10.7 0.0 2.0 1 1 1 2 2 2 0 CpXC protein zf-C2H2_4 PF13894.6 AAL62600.1 - 0.026 15.3 1.1 9.4 7.4 0.0 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger Ogr_Delta PF04606.12 AAL62600.1 - 0.028 14.4 0.4 6.1 6.9 0.0 2.1 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zf_UBZ PF18439.1 AAL62600.1 - 0.031 13.9 1.0 0.23 11.1 0.1 2.1 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger NMD3 PF04981.13 AAL62600.1 - 0.032 13.7 0.4 0.034 13.6 0.4 1.0 1 0 0 1 1 1 0 NMD3 family HypA PF01155.19 AAL62600.1 - 0.046 13.7 0.3 0.049 13.6 0.3 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF1936 PF09151.10 AAL62600.1 - 0.056 13.4 2.9 0.076 12.9 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1936) Zn_Tnp_IS1595 PF12760.7 AAL62600.1 - 0.074 13.0 4.4 1.4 9.0 0.2 2.1 1 1 1 2 2 2 0 Transposase zinc-ribbon domain DUF2256 PF10013.9 AAL62600.1 - 0.083 13.0 1.1 7 6.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) eIF-5_eIF-2B PF01873.17 AAL62600.1 - 0.11 12.4 0.2 0.12 12.2 0.2 1.1 1 0 0 1 1 1 0 Domain found in IF2B/IF5 Rubredoxin_2 PF18073.1 AAL62600.1 - 0.12 12.2 3.6 1.4 8.7 0.1 2.1 2 0 0 2 2 2 0 Rubredoxin metal binding domain YacG PF03884.14 AAL62600.1 - 0.13 12.0 1.0 3.8 7.3 0.1 2.1 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG Prok-RING_1 PF14446.6 AAL62600.1 - 0.14 12.1 3.9 0.25 11.3 3.9 1.4 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-LITAF-like PF10601.9 AAL62600.1 - 0.18 12.1 2.3 12 6.3 0.1 2.1 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain ADK_lid PF05191.14 AAL62600.1 - 0.2 11.7 4.3 0.94 9.5 0.6 2.2 2 0 0 2 2 2 0 Adenylate kinase, active site lid zf-ACC PF17848.1 AAL62600.1 - 0.2 11.8 3.8 8.1 6.6 0.3 2.2 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain zf-C2H2 PF00096.26 AAL62600.1 - 0.23 12.0 3.5 6.1 7.5 0.7 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type zinc_ribbon_9 PF14369.6 AAL62600.1 - 0.33 11.2 4.9 2.5 8.5 1.4 2.2 1 1 1 2 2 2 0 zinc-ribbon zf-C4_Topoisom PF01396.19 AAL62600.1 - 0.37 10.6 6.8 1.8 8.4 0.7 2.3 1 1 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Zn-C2H2_12 PF18112.1 AAL62600.1 - 0.39 11.2 3.7 3.8 8.1 0.5 2.1 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-RING_7 PF02591.15 AAL62600.1 - 0.71 10.1 6.9 1.6 9.0 0.5 2.2 1 1 1 2 2 2 0 C4-type zinc ribbon domain DNA_ligase_ZBD PF03119.16 AAL62600.1 - 1.1 9.3 8.8 11 6.1 4.7 2.5 1 1 1 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zinc_ribbon_5 PF13719.6 AAL62600.1 - 1.8 8.4 5.3 6.8 6.5 5.3 1.8 1 1 0 1 1 1 0 zinc-ribbon domain DUF1610 PF07754.11 AAL62600.1 - 2 8.5 7.9 2.9 7.9 0.6 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1610) zf-CCHC_5 PF14787.6 AAL62600.1 - 4.1 7.2 6.7 3.5 7.4 1.0 2.1 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger NUDIX PF00293.28 AAL62603.1 - 5.2e-20 71.8 1.2 6.4e-20 71.5 1.2 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 AAL62603.1 - 0.0065 16.5 0.2 0.013 15.5 0.2 1.6 1 1 0 1 1 1 1 NUDIX domain Radical_SAM PF04055.21 AAL62604.1 - 9.6e-20 71.6 0.0 3e-19 70.0 0.0 1.8 1 1 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.12 AAL62604.1 - 9.6e-19 67.5 0.0 1.7e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 Wyosine base formation Carla_C4 PF01623.17 AAL62604.1 - 0.28 11.2 1.6 0.54 10.3 1.6 1.4 1 0 0 1 1 1 0 Carlavirus putative nucleic acid binding protein DUF86 PF01934.17 AAL62606.1 - 5.9e-18 64.9 0.0 6.7e-18 64.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF86 Polbeta PF18765.1 AAL62607.1 - 3.4e-13 49.5 0.0 4.8e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 AAL62607.1 - 3.2e-06 27.4 0.2 4.5e-06 26.9 0.2 1.3 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 AAL62608.1 - 1.7e-07 31.2 0.0 2.2e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 AAL62608.1 - 2.6e-07 30.9 0.0 3.7e-07 30.3 0.0 1.3 1 1 0 1 1 1 1 Nucleotidyltransferase domain HEPN PF05168.14 AAL62609.1 - 2.8e-28 98.4 0.0 3.2e-28 98.2 0.0 1.0 1 0 0 1 1 1 1 HEPN domain TENA_THI-4 PF03070.16 AAL62610.1 - 3.9e-44 151.0 0.5 4.6e-44 150.7 0.5 1.1 1 0 0 1 1 1 1 TENA/THI-4/PQQC family TENA_THI-4 PF03070.16 AAL62611.1 - 5.4e-12 46.0 0.1 7.7e-12 45.5 0.1 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family AAA_14 PF13173.6 AAL62612.1 - 7.5e-22 77.8 0.0 1.2e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 AAL62612.1 - 0.0013 18.7 0.0 0.0064 16.4 0.0 2.0 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 AAL62612.1 - 0.036 14.3 0.0 0.14 12.4 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 AAL62612.1 - 0.069 13.5 0.0 1.4 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain zf-SNAP50_C PF12251.8 AAL62613.1 - 0.022 14.4 1.9 0.025 14.3 1.9 1.0 1 0 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal zf-C6H2 PF15801.5 AAL62613.1 - 0.6 10.5 9.5 14 6.1 9.5 2.1 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-FCS PF06467.14 AAL62613.1 - 0.78 9.7 10.0 4 7.5 10.0 2.2 1 1 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif Thi4 PF01946.17 AAL62614.1 - 1.1e-72 244.1 0.2 1.3e-72 243.9 0.2 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 AAL62614.1 - 6.8e-14 52.2 2.9 1e-07 31.9 0.8 2.1 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AAL62614.1 - 6.1e-09 36.0 0.5 1.7e-08 34.6 0.4 1.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 AAL62614.1 - 6.2e-09 35.4 2.8 4.1e-07 29.4 0.6 2.9 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.14 AAL62614.1 - 1.4e-08 34.3 0.2 2.1e-08 33.8 0.1 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AAL62614.1 - 8.2e-08 31.9 0.0 1.2e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 AAL62614.1 - 1.4e-07 31.2 0.3 2.2e-07 30.6 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 AAL62614.1 - 6.2e-06 25.2 0.1 8.4e-06 24.7 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.24 AAL62614.1 - 9.8e-05 21.8 0.1 0.00017 21.0 0.1 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 AAL62614.1 - 0.00043 19.6 0.0 0.00085 18.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 AAL62614.1 - 0.00097 18.3 0.3 0.0019 17.3 0.0 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.22 AAL62614.1 - 0.001 18.3 1.0 0.0018 17.5 0.8 1.4 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 AAL62614.1 - 0.0011 19.5 0.2 0.0052 17.3 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 AAL62614.1 - 0.0016 18.5 0.0 0.0032 17.5 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 AAL62614.1 - 0.014 15.4 1.5 0.018 15.0 0.3 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 AAL62614.1 - 0.022 14.7 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 AAL62614.1 - 0.024 14.0 0.0 0.048 13.0 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 AAL62614.1 - 0.038 13.3 0.0 0.085 12.1 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 AAL62614.1 - 0.06 13.8 0.2 0.14 12.7 0.1 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding Trp_halogenase PF04820.14 AAL62614.1 - 0.068 12.0 0.9 0.085 11.7 0.3 1.4 2 0 0 2 2 2 0 Tryptophan halogenase Sugar_tr PF00083.24 AAL62615.1 - 7.2e-25 87.8 23.7 4.3e-24 85.2 22.8 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 AAL62615.1 - 5.2e-20 71.7 43.2 5.2e-20 71.7 43.2 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily HypA PF01155.19 AAL62616.1 - 8e-05 22.6 1.4 0.00013 21.9 1.4 1.3 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 AAL62616.1 - 0.00039 20.5 4.3 0.00073 19.6 4.3 1.4 1 0 0 1 1 1 1 Zinc ribbon domain DZR PF12773.7 AAL62616.1 - 0.0074 16.3 1.2 0.012 15.6 1.2 1.3 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.6 AAL62616.1 - 0.012 15.0 4.2 0.012 15.0 4.2 1.8 2 1 0 2 2 2 0 zinc-ribbon domain RNA_POL_M_15KD PF02150.16 AAL62616.1 - 0.016 15.1 0.6 3.8 7.5 0.1 2.3 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Nudix_N_2 PF14803.6 AAL62616.1 - 0.029 14.3 3.1 1.5 8.8 0.2 2.3 2 0 0 2 2 2 0 Nudix N-terminal zf-C3HC4_3 PF13920.6 AAL62616.1 - 0.032 14.1 0.2 0.055 13.3 0.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-dskA_traR PF01258.17 AAL62616.1 - 0.037 14.0 3.3 0.53 10.3 0.3 2.4 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger Anti-TRAP PF15777.5 AAL62616.1 - 0.057 13.4 1.0 0.093 12.7 1.0 1.4 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein zinc_ribbon_2 PF13240.6 AAL62616.1 - 0.083 12.6 6.1 1.5 8.6 6.1 2.4 1 1 0 1 1 1 0 zinc-ribbon domain DiS_P_DiS PF06750.13 AAL62616.1 - 0.093 12.9 0.6 6.4 7.0 0.2 2.4 1 1 1 2 2 2 0 Bacterial Peptidase A24 N-terminal domain OrfB_Zn_ribbon PF07282.11 AAL62616.1 - 0.13 12.2 2.9 0.2 11.6 2.9 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DUF35_N PF12172.8 AAL62616.1 - 0.15 12.0 2.2 8.3 6.4 0.1 2.3 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Desulfoferrod_N PF06397.12 AAL62616.1 - 0.28 10.8 6.8 0.13 11.9 3.2 2.3 2 1 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain DNA_RNApol_7kD PF03604.13 AAL62616.1 - 0.82 9.4 4.6 1.8 8.3 4.6 1.6 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit zf-FPG_IleRS PF06827.14 AAL62616.1 - 1.1 9.2 6.2 8.2 6.4 0.9 2.2 1 1 1 2 2 2 0 Zinc finger found in FPG and IleRS Methyltransf_23 PF13489.6 AAL62617.1 - 3.1e-07 30.4 0.0 4e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAL62617.1 - 0.0018 18.1 0.0 0.0042 16.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAL62617.1 - 0.03 15.0 0.0 0.068 13.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 AAL62617.1 - 0.061 14.1 0.0 0.15 12.8 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain SUI1 PF01253.22 AAL62617.1 - 0.21 12.1 0.0 0.35 11.4 0.0 1.3 1 0 0 1 1 1 0 Translation initiation factor SUI1 CRISPR_Cas6 PF10040.9 AAL62618.1 - 6e-16 58.9 1.5 1e-15 58.1 1.5 1.4 1 0 0 1 1 1 1 CRISPR-associated endoribonuclease Cas6 Cas_Cas4 PF01930.17 AAL62619.1 - 3.5e-15 56.5 0.0 4.1e-15 56.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF83 PDDEXK_1 PF12705.7 AAL62619.1 - 1e-09 38.7 0.4 2.3e-09 37.6 0.4 1.5 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily SDH_C PF18317.1 AAL62619.1 - 0.015 15.1 4.0 0.03 14.1 0.1 2.8 3 0 0 3 3 3 0 Shikimate 5'-dehydrogenase C-terminal domain CRISPR_Cas2 PF09827.9 AAL62620.1 - 3.4e-19 68.8 0.1 4.1e-19 68.5 0.1 1.1 1 0 0 1 1 1 1 CRISPR associated protein Cas2 RcsD_ABL PF16359.5 AAL62620.1 - 0.066 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 RcsD-ABL domain DUF5042 PF16445.5 AAL62620.1 - 0.072 11.5 0.0 0.09 11.1 0.0 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF5042) CGI-121 PF08617.10 AAL62620.1 - 0.098 12.8 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 Kinase binding protein CGI-121 Cas_Cas1 PF01867.16 AAL62621.1 - 9e-61 205.5 0.0 1.1e-60 205.2 0.0 1.1 1 0 0 1 1 1 1 CRISPR associated protein Cas1 Hydrolase PF00702.26 AAL62621.1 - 0.13 12.5 0.4 0.35 11.1 0.4 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Csa1 PF06023.12 AAL62622.1 - 8.9e-108 360.1 0.0 1e-107 359.8 0.0 1.0 1 0 0 1 1 1 1 CRISPR-associated exonuclease Csa1 HTH_29 PF13551.6 AAL62623.1 - 2.5e-07 30.6 0.0 1.2e-06 28.5 0.0 2.1 2 1 0 2 2 2 1 Winged helix-turn helix HTH_IclR PF09339.10 AAL62623.1 - 3e-07 30.1 0.0 9.8e-07 28.5 0.0 1.9 2 0 0 2 2 1 1 IclR helix-turn-helix domain HTH_5 PF01022.20 AAL62623.1 - 4.8e-07 29.5 0.1 4.1e-06 26.6 0.0 2.4 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family TrmB PF01978.19 AAL62623.1 - 4.8e-06 26.4 0.1 9.4e-06 25.4 0.1 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_28 PF13518.6 AAL62623.1 - 2.8e-05 24.2 0.0 0.00046 20.3 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_40 PF14493.6 AAL62623.1 - 0.00016 22.1 0.1 0.0005 20.5 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_20 PF12840.7 AAL62623.1 - 0.00017 21.6 1.1 0.00026 21.0 0.1 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain DprA_WH PF17782.1 AAL62623.1 - 0.0027 17.8 0.4 0.0079 16.3 0.1 2.0 2 0 0 2 2 2 1 DprA winged helix domain HTH_11 PF08279.12 AAL62623.1 - 0.0033 17.3 0.1 0.0069 16.3 0.1 1.5 1 0 0 1 1 1 1 HTH domain HTH_24 PF13412.6 AAL62623.1 - 0.0039 16.7 0.1 0.013 15.0 0.1 2.0 1 1 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 AAL62623.1 - 0.0056 16.5 0.2 0.016 15.1 0.1 1.8 2 0 0 2 2 2 1 MarR family HTH_36 PF13730.6 AAL62623.1 - 0.017 15.0 0.1 0.064 13.2 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.6 AAL62623.1 - 0.019 14.8 0.0 0.076 12.8 0.0 2.1 2 1 0 2 2 1 0 Homeodomain-like domain HTH_47 PF16221.5 AAL62623.1 - 0.022 14.3 0.0 0.049 13.2 0.0 1.6 1 0 0 1 1 1 0 winged helix-turn-helix Rrf2 PF02082.20 AAL62623.1 - 0.03 14.6 0.1 0.098 13.0 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator MarR PF01047.22 AAL62623.1 - 0.043 13.8 0.0 0.097 12.6 0.0 1.6 1 0 0 1 1 1 0 MarR family TnsD PF15978.5 AAL62623.1 - 0.047 12.7 0.0 0.061 12.3 0.0 1.1 1 0 0 1 1 1 0 Tn7-like transposition protein D HTH_38 PF13936.6 AAL62623.1 - 0.053 13.3 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain GerE PF00196.19 AAL62623.1 - 0.07 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_12 PF08461.10 AAL62623.1 - 0.07 13.1 0.2 0.13 12.2 0.2 1.6 1 1 0 1 1 1 0 Ribonuclease R winged-helix domain DUF4423 PF14394.6 AAL62623.1 - 0.091 12.5 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) AAA_15 PF13175.6 AAL62624.1 - 6.2e-08 32.7 0.0 0.0004 20.2 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 AAL62624.1 - 1.7e-06 28.0 0.0 0.0049 16.7 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 AAL62624.1 - 0.00017 21.9 0.0 0.52 10.6 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 AAL62624.1 - 0.0028 18.2 0.0 0.0037 17.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 AAL62624.1 - 0.0066 16.8 0.0 0.013 15.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 AAL62624.1 - 0.011 15.5 0.0 0.079 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 AAL62624.1 - 0.011 16.3 0.0 0.019 15.5 0.0 1.5 2 0 0 2 2 1 0 ABC transporter AAA_16 PF13191.6 AAL62624.1 - 0.036 14.5 0.0 0.08 13.3 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 AAL62624.1 - 0.092 13.2 0.1 0.51 10.8 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 AAL62624.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 AAL62624.1 - 0.11 13.1 0.0 1.1 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 AAL62624.1 - 0.14 11.9 0.4 8.9 6.0 0.0 2.7 2 1 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain Gtr1_RagA PF04670.12 AAL62624.1 - 0.14 11.5 0.0 0.34 10.2 0.0 1.6 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region DUF3584 PF12128.8 AAL62624.1 - 0.26 8.8 0.0 0.32 8.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Cas_Csa4 PF09703.10 AAL62625.1 - 1.7e-123 412.5 0.0 1.9e-123 412.3 0.0 1.0 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Csa4) HD PF01966.22 AAL62626.1 - 2.8e-05 24.3 0.2 4.6e-05 23.6 0.2 1.4 1 0 0 1 1 1 1 HD domain HD_6 PF18019.1 AAL62626.1 - 0.04 14.0 0.1 0.2 11.7 0.1 1.9 1 1 0 1 1 1 0 HD domain DEAD PF00270.29 AAL62627.1 - 3.9e-16 59.3 0.0 1.7e-14 54.0 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AAL62627.1 - 5.8e-08 33.1 0.1 1.2e-07 32.0 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 AAL62627.1 - 4.5e-07 30.0 0.0 1.2e-06 28.6 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Cas_Cas5d PF09704.10 AAL62628.1 - 4e-20 72.6 0.1 4.8e-20 72.4 0.1 1.1 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Cas5) DevR PF01905.16 AAL62629.1 - 1.2e-66 224.6 0.0 1.4e-66 224.3 0.0 1.1 1 0 0 1 1 1 1 CRISPR-associated negative auto-regulator DevR/Csa2 DUF296 PF03479.15 AAL62629.1 - 0.076 13.4 0.1 0.17 12.3 0.1 1.5 1 0 0 1 1 1 0 Plants and Prokaryotes Conserved (PCC) domain MtaB PF12176.8 AAL62630.1 - 0.0071 15.2 0.1 0.0085 14.9 0.1 1.0 1 0 0 1 1 1 1 Methanol-cobalamin methyltransferase B subunit PHA_synth_III_E PF09712.10 AAL62630.1 - 0.042 12.9 0.0 0.047 12.8 0.0 1.0 1 0 0 1 1 1 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) JmjN PF02375.17 AAL62630.1 - 0.078 13.0 0.1 4.5 7.3 0.0 2.4 2 0 0 2 2 2 0 jmjN domain SesA PF17107.5 AAL62630.1 - 0.1 12.8 0.1 0.15 12.2 0.0 1.4 1 1 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DinB PF05163.12 AAL62630.1 - 0.14 12.1 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 DinB family CRISPR_Cas6 PF10040.9 AAL62631.1 - 1.2e-16 61.1 0.5 2.7e-16 60.0 0.5 1.6 2 0 0 2 2 2 1 CRISPR-associated endoribonuclease Cas6 Cas6_N PF17952.1 AAL62631.1 - 0.19 12.0 0.0 0.32 11.3 0.0 1.3 1 0 0 1 1 1 0 Cas6 N-terminal domain ATP-synt_ab_Xtn PF16886.5 AAL62632.1 - 0.035 14.0 0.0 0.04 13.8 0.0 1.2 1 0 0 1 1 1 0 ATPsynthase alpha/beta subunit N-term extension SAICAR_synt PF01259.18 AAL62634.1 - 1.6e-43 149.2 0.0 1.9e-43 148.9 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase GARS_A PF01071.19 AAL62635.1 - 5.5e-35 120.9 0.0 1.3e-34 119.7 0.0 1.7 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 AAL62635.1 - 1.6e-20 73.7 0.1 4e-20 72.4 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 AAL62635.1 - 1.2e-10 41.5 0.0 3.8e-10 39.9 0.0 1.9 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain ATP-grasp_4 PF13535.6 AAL62635.1 - 0.0013 18.3 0.1 0.015 14.9 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.17 AAL62635.1 - 0.007 15.9 0.1 0.018 14.5 0.0 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 AAL62635.1 - 0.024 14.7 0.0 0.11 12.6 0.0 2.0 1 1 0 1 1 1 0 ATP-grasp domain GSH-S_ATP PF02955.16 AAL62635.1 - 0.033 13.6 0.0 0.065 12.6 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain ATPgrasp_ST PF14397.6 AAL62635.1 - 0.15 11.3 0.0 0.52 9.5 0.0 1.8 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Pribosyltran PF00156.27 AAL62636.1 - 6e-12 45.4 0.6 9.9e-12 44.7 0.6 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Formyl_trans_N PF00551.19 AAL62637.1 - 2.2e-30 105.8 0.0 3.1e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase THF_DHG_CYH_C PF02882.19 AAL62638.1 - 4e-42 143.2 0.0 6.6e-42 142.5 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 AAL62638.1 - 1.5e-23 83.3 0.0 2.3e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AIRS_C PF02769.22 AAL62639.1 - 2.1e-18 66.9 0.1 4.8e-18 65.8 0.0 1.6 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 AAL62639.1 - 3.6e-12 46.8 1.3 5.9e-12 46.1 1.3 1.4 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain GATase_5 PF13507.6 AAL62640.1 - 1.7e-38 132.2 0.0 1.6e-36 125.8 0.0 2.0 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 AAL62640.1 - 2.6e-09 37.1 0.0 4.3e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.14 AAL62640.1 - 7.8e-09 35.4 0.0 1.4e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 AAL62640.1 - 4.1e-07 29.9 0.0 4.3e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AAL62640.1 - 0.0014 18.5 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase C26 YkuD PF03734.14 AAL62640.1 - 0.0061 17.0 0.0 0.01 16.3 0.0 1.3 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain PurS PF02700.14 AAL62641.1 - 1.2e-15 57.5 0.0 1.4e-15 57.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoribosylformylglycinamidine (FGAM) synthase AIRS PF00586.24 AAL62642.1 - 4.9e-45 152.1 1.2 1.3e-22 80.2 0.1 2.4 2 0 0 2 2 2 2 AIR synthase related protein, N-terminal domain AIRS_C PF02769.22 AAL62642.1 - 4.5e-38 130.8 3.9 3.1e-24 85.9 0.5 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_linker PF18072.1 AAL62642.1 - 2e-10 41.1 0.1 3.5e-10 40.3 0.1 1.4 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain GATase_6 PF13522.6 AAL62643.1 - 2.4e-09 37.5 0.0 5.7e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 AAL62643.1 - 2.4e-08 33.6 0.3 4.5e-08 32.8 0.3 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_7 PF13537.6 AAL62643.1 - 6.4e-08 32.6 0.0 1.2e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain PaREP1 PF05942.11 AAL62646.1 - 8e-28 96.7 2.6 1.1e-27 96.2 2.6 1.2 1 0 0 1 1 1 1 Archaeal PaREP1/PaREP8 family ATP-grasp PF02222.22 AAL62647.1 - 6.2e-41 139.8 0.0 8.8e-41 139.3 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 AAL62647.1 - 6.5e-14 51.4 0.0 1.1e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain EVE PF01878.18 AAL62650.1 - 3.1e-17 62.9 0.0 7.6e-17 61.7 0.0 1.7 2 0 0 2 2 2 1 EVE domain Hydrolase PF00702.26 AAL62650.1 - 0.077 13.3 0.7 0.21 11.9 0.7 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Zn_Tnp_IS1595 PF12760.7 AAL62651.1 - 0.00028 20.8 1.1 0.00038 20.4 1.1 1.2 1 0 0 1 1 1 1 Transposase zinc-ribbon domain TF_Zn_Ribbon PF08271.12 AAL62651.1 - 0.0066 15.9 4.2 0.065 12.8 4.2 2.0 1 1 0 1 1 1 1 TFIIB zinc-binding HypA PF01155.19 AAL62651.1 - 0.007 16.4 0.3 0.73 9.9 0.1 2.0 1 1 1 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF3268 PF11672.8 AAL62651.1 - 0.0099 16.2 0.6 0.01 16.1 0.6 1.1 1 0 0 1 1 1 1 zinc-finger-containing domain Zn-ribbon_8 PF09723.10 AAL62651.1 - 0.01 16.0 2.4 2.7 8.2 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain zf-TFIIB PF13453.6 AAL62651.1 - 0.05 12.9 1.2 0.11 11.8 1.2 1.5 1 1 0 1 1 1 0 Transcription factor zinc-finger zf-ribbon_3 PF13248.6 AAL62651.1 - 0.091 12.2 0.2 0.091 12.2 0.2 1.9 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 AAL62651.1 - 0.11 12.3 0.3 0.11 12.3 0.3 2.0 2 0 0 2 2 2 0 zinc-ribbon domain TFIIS_C PF01096.18 AAL62651.1 - 0.19 11.6 2.7 3.3 7.6 0.2 2.1 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-ISL3 PF14690.6 AAL62651.1 - 0.89 10.3 0.1 0.89 10.3 0.1 2.8 2 1 1 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Rubredoxin_2 PF18073.1 AAL62651.1 - 1.5 8.6 7.1 1.6 8.5 1.1 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain N6_Mtase PF02384.16 AAL62652.1 - 4.7e-07 29.4 0.0 0.0003 20.1 0.0 2.4 2 0 0 2 2 2 2 N-6 DNA Methylase Eco57I PF07669.11 AAL62652.1 - 0.0069 16.9 0.0 0.025 15.1 0.0 1.9 1 1 0 1 1 1 1 Eco57I restriction-modification methylase Methyltransf_23 PF13489.6 AAL62652.1 - 0.042 13.7 0.0 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain VSG_B PF13206.6 AAL62652.1 - 0.077 12.2 0.5 0.14 11.3 0.5 1.3 1 0 0 1 1 1 0 Trypanosomal VSG domain EVC2_like PF12297.8 AAL62652.1 - 0.077 11.7 3.5 0.12 11.0 3.5 1.2 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein UPF0020 PF01170.18 AAL62652.1 - 0.11 12.1 0.0 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 YfdX PF10938.8 AAL62652.1 - 0.21 11.5 0.5 0.78 9.7 0.0 2.0 2 0 0 2 2 2 0 YfdX protein TPD52 PF04201.15 AAL62652.1 - 0.42 10.2 3.1 0.81 9.3 3.1 1.4 1 0 0 1 1 1 0 Tumour protein D52 family Lon_2 PF13337.6 AAL62653.1 - 7.9e-150 499.4 0.0 8.9e-150 499.2 0.0 1.0 1 0 0 1 1 1 1 Putative ATP-dependent Lon protease AAA_14 PF13173.6 AAL62653.1 - 0.029 14.4 0.0 0.13 12.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain DUF853 PF05872.12 AAL62654.1 - 7e-09 34.8 0.0 0.00055 18.7 0.0 2.2 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF853) DUF87 PF01935.17 AAL62654.1 - 9.3e-09 35.7 0.0 3.4e-08 33.8 0.0 2.0 2 0 0 2 2 2 1 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 AAL62654.1 - 3.7e-06 26.1 0.0 5.9e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.18 AAL62654.1 - 8e-06 25.4 0.1 7.9e-05 22.1 0.0 2.0 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA PF00004.29 AAL62654.1 - 8e-06 26.3 0.1 0.015 15.7 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AAL62654.1 - 0.0018 18.5 0.0 0.2 12.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 AAL62654.1 - 0.013 16.0 0.0 0.062 13.8 0.0 2.0 2 0 0 2 2 2 0 ABC transporter ResIII PF04851.15 AAL62654.1 - 0.024 14.7 0.1 9.8 6.1 0.0 2.5 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_10 PF12846.7 AAL62654.1 - 0.043 12.7 0.0 1.3 7.8 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain Zot PF05707.12 AAL62654.1 - 0.048 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) NACHT PF05729.12 AAL62654.1 - 0.051 13.5 0.5 0.48 10.3 0.1 2.2 2 0 0 2 2 2 0 NACHT domain Pox_A32 PF04665.12 AAL62654.1 - 0.052 13.0 0.0 0.085 12.3 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein T2SSE PF00437.20 AAL62654.1 - 0.11 11.6 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein CbiA PF01656.23 AAL62654.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.6 AAL62654.1 - 0.12 12.9 0.0 0.34 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 AAL62654.1 - 0.14 11.8 0.2 0.9 9.1 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 AAL62654.1 - 0.18 11.8 0.0 0.43 10.6 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 AAL62654.1 - 0.22 11.7 0.1 0.49 10.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 AAL62654.1 - 0.22 11.1 0.1 0.37 10.4 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NurA PF09376.10 AAL62655.1 - 5.2e-23 82.0 0.1 6.6e-23 81.6 0.1 1.1 1 0 0 1 1 1 1 NurA domain Toxin_23 PF08093.11 AAL62656.1 - 0.054 13.7 0.4 0.054 13.7 0.4 2.2 3 0 0 3 3 3 0 Magi 5 toxic peptide family Ribonuclease_P PF00825.18 AAL62657.1 - 0.037 14.1 0.0 0.068 13.3 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease P Tn7_Tnp_TnsA_N PF08722.11 AAL62657.1 - 0.067 13.4 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 TnsA endonuclease N terminal Helicase_PWI PF18149.1 AAL62657.1 - 0.069 13.3 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 N-terminal helicase PWI domain AIRC PF00731.20 AAL62658.1 - 5.7e-65 217.4 0.3 6.5e-65 217.2 0.3 1.0 1 0 0 1 1 1 1 AIR carboxylase MazG-like PF12643.7 AAL62658.1 - 0.052 13.8 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 MazG-like family NUDIX PF00293.28 AAL62659.1 - 6.9e-19 68.2 0.3 8.9e-19 67.8 0.3 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 AAL62659.1 - 0.0029 17.6 0.1 0.004 17.1 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain LZ_Tnp_IS481 PF13011.6 AAL62661.1 - 0.0016 18.9 0.1 0.0027 18.2 0.1 1.3 1 0 0 1 1 1 1 leucine-zipper of insertion element IS481 HTH_32 PF13565.6 AAL62661.1 - 0.037 14.6 0.3 0.081 13.6 0.3 1.5 1 0 0 1 1 1 0 Homeodomain-like domain PALP PF00291.25 AAL62663.1 - 1.8e-45 155.6 0.4 2.2e-45 155.3 0.4 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Methyltransf_31 PF13847.6 AAL62664.1 - 1.4e-15 57.4 0.0 1.9e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAL62664.1 - 2.2e-14 53.9 0.1 4.2e-14 53.0 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AAL62664.1 - 6.9e-12 45.2 0.0 9.8e-12 44.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 AAL62664.1 - 3.9e-11 43.4 0.0 9e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 AAL62664.1 - 6.2e-10 38.9 0.1 7.6e-10 38.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 AAL62664.1 - 9.3e-10 38.4 0.0 1.1e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.18 AAL62664.1 - 1e-06 28.6 0.0 4.5e-06 26.5 0.0 1.9 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_23 PF13489.6 AAL62664.1 - 2.3e-06 27.6 0.0 2.3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAL62664.1 - 1.3e-05 25.8 0.0 2.6e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AAL62664.1 - 3.1e-05 23.4 0.0 8.1e-05 22.1 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Met_10 PF02475.16 AAL62664.1 - 0.0013 18.6 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_32 PF13679.6 AAL62664.1 - 0.0042 17.1 0.0 0.0077 16.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 AAL62664.1 - 0.0045 16.4 0.0 0.0063 15.9 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB NodS PF05401.11 AAL62664.1 - 0.013 15.1 0.1 0.022 14.4 0.1 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) DUF43 PF01861.16 AAL62664.1 - 0.017 14.3 0.0 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Methyltransf_4 PF02390.17 AAL62664.1 - 0.018 14.5 0.7 0.041 13.3 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase tRNA_U5-meth_tr PF05958.11 AAL62664.1 - 0.023 13.7 0.0 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_24 PF13578.6 AAL62664.1 - 0.028 15.4 0.0 0.41 11.7 0.0 2.1 1 1 1 2 2 2 0 Methyltransferase domain ADH_zinc_N PF00107.26 AAL62664.1 - 0.031 14.2 0.0 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase PCMT PF01135.19 AAL62664.1 - 0.032 14.0 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 AAL62664.1 - 0.048 13.8 0.0 0.07 13.2 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_15 PF09445.10 AAL62664.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_16 PF10294.9 AAL62664.1 - 0.16 11.7 0.1 0.7 9.6 0.0 1.9 1 1 1 2 2 2 0 Lysine methyltransferase Band_7 PF01145.25 AAL62665.1 - 5.4e-20 72.1 6.5 5.4e-20 72.1 6.5 1.6 1 1 1 2 2 2 1 SPFH domain / Band 7 family DUF1995 PF09353.10 AAL62665.1 - 0.96 9.4 3.9 1.5 8.8 3.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1995) HTH_27 PF13463.6 AAL62666.1 - 0.0033 17.9 0.0 0.0045 17.5 0.0 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR_2 PF12802.7 AAL62666.1 - 0.012 15.5 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_42 PF06224.12 AAL62666.1 - 0.03 13.9 0.1 0.03 13.9 0.1 1.1 1 0 0 1 1 1 0 Winged helix DNA-binding domain Penicillinase_R PF03965.16 AAL62666.1 - 0.037 14.4 0.0 0.049 14.0 0.0 1.1 1 0 0 1 1 1 0 Penicillinase repressor TrmB PF01978.19 AAL62666.1 - 0.041 13.8 0.1 0.061 13.2 0.1 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB RPA_C PF08784.11 AAL62666.1 - 0.071 13.8 0.0 0.099 13.3 0.0 1.2 1 0 0 1 1 1 0 Replication protein A C terminal HTH_Crp_2 PF13545.6 AAL62666.1 - 0.092 12.7 0.1 0.18 11.8 0.1 1.5 1 1 0 1 1 1 0 Crp-like helix-turn-helix domain DUF4131 PF13567.6 AAL62666.1 - 0.1 12.2 1.3 0.11 12.1 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) HTH_15 PF12324.8 AAL62666.1 - 0.11 12.5 0.1 0.2 11.7 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase DUF2250 PF10007.9 AAL62666.1 - 0.17 12.1 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) DUF4423 PF14394.6 AAL62666.1 - 0.17 11.6 0.0 0.22 11.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) DUF2244 PF10003.9 AAL62666.1 - 1.8 8.3 4.7 2.7 7.7 4.7 1.2 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) Peptidase_S24 PF00717.23 AAL62667.1 - 1e-05 25.4 0.0 2.3e-05 24.3 0.0 1.6 2 0 0 2 2 2 1 Peptidase S24-like Alpha-amylase_N PF02903.14 AAL62668.1 - 0.012 15.7 0.0 0.015 15.4 0.0 1.2 1 0 0 1 1 1 0 Alpha amylase, N-terminal ig-like domain DJ-1_PfpI PF01965.24 AAL62669.1 - 1.6e-49 167.9 0.0 1.9e-49 167.7 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.14 AAL62669.1 - 0.00056 19.6 0.0 0.00082 19.0 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Catalase_C PF18011.1 AAL62669.1 - 0.0014 18.2 0.0 0.0029 17.3 0.0 1.5 1 1 0 1 1 1 1 C-terminal domain found in long catalases GATase PF00117.28 AAL62669.1 - 0.002 18.0 0.0 0.0025 17.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I ThiJ_like PF17124.5 AAL62669.1 - 0.0029 17.3 0.0 0.041 13.6 0.0 2.1 2 0 0 2 2 2 1 ThiJ/PfpI family-like DUF4328 PF14219.6 AAL62670.1 - 0.026 14.1 1.9 0.031 13.8 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) PRA1 PF03208.19 AAL62670.1 - 1.2 8.7 7.3 1.5 8.4 7.3 1.2 1 0 0 1 1 1 0 PRA1 family protein CitMHS PF03600.16 AAL62670.1 - 1.8 7.7 9.9 2.7 7.1 9.9 1.3 1 0 0 1 1 1 0 Citrate transporter Pox_P21 PF05313.12 AAL62670.1 - 2.5 7.6 6.8 3.2 7.3 6.8 1.2 1 0 0 1 1 1 0 Poxvirus P21 membrane protein DUF3481 PF11980.8 AAL62670.1 - 3.1 7.6 5.2 6.2 6.6 0.7 2.5 1 1 1 2 2 2 0 C-terminal domain of neuropilin glycoprotein ABC_tran PF00005.27 AAL62671.1 - 2e-28 99.6 0.0 3e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAL62671.1 - 5.9e-11 42.7 0.6 3.6e-05 23.7 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 AAL62671.1 - 3.1e-05 24.6 0.1 7.8e-05 23.3 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) AAA PF00004.29 AAL62671.1 - 0.0034 17.8 0.2 0.038 14.4 0.2 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 AAL62671.1 - 0.005 16.5 0.1 0.012 15.3 0.1 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_23 PF13476.6 AAL62671.1 - 0.0057 17.2 0.0 0.0094 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AAL62671.1 - 0.0061 16.3 0.1 0.012 15.3 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAL62671.1 - 0.049 14.0 0.0 0.075 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain IMS PF00817.20 AAL62671.1 - 0.095 12.7 0.1 0.2 11.7 0.1 1.5 1 1 0 1 1 1 0 impB/mucB/samB family AAA_29 PF13555.6 AAL62671.1 - 0.13 12.0 0.2 0.29 10.9 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 AAL62671.1 - 0.15 12.0 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain MutS_V PF00488.21 AAL62671.1 - 0.15 12.1 0.0 0.95 9.5 0.0 2.1 2 0 0 2 2 2 0 MutS domain V AAA_15 PF13175.6 AAL62671.1 - 0.21 11.2 0.0 2.9 7.5 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain ABC2_membrane PF01061.24 AAL62672.1 - 1.9e-33 115.7 19.9 2.5e-33 115.3 19.9 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 AAL62672.1 - 8.9e-14 51.3 15.9 8.9e-14 51.3 15.9 1.3 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 AAL62672.1 - 3.5e-07 30.4 8.9 6.2e-07 29.5 8.7 1.6 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 AAL62672.1 - 0.072 12.4 18.7 0.49 9.6 18.8 2.3 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF846 PF05832.12 AAL62672.1 - 2.3 8.3 6.3 0.32 11.0 0.9 2.2 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF846) OATP PF03137.20 AAL62672.1 - 2.3 6.4 11.1 9.1 4.4 11.1 1.9 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Rieske PF00355.26 AAL62673.1 - 2.1e-10 40.4 0.0 2.3e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain NusG_II PF07009.11 AAL62673.1 - 0.11 12.7 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 NusG domain II HEPN PF05168.14 AAL62674.1 - 3.1e-29 101.5 1.2 3.2e-29 101.4 0.2 1.5 2 0 0 2 2 2 1 HEPN domain NTP_transf_2 PF01909.23 AAL62674.1 - 1.1e-10 41.6 0.0 2e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 AAL62674.1 - 7.9e-08 32.3 0.0 1.5e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase DUF294 PF03445.13 AAL62674.1 - 0.09 12.6 0.0 7.9 6.3 0.0 2.5 1 1 1 2 2 2 0 Putative nucleotidyltransferase DUF294 Sod_Fe_C PF02777.18 AAL62675.1 - 8.6e-36 122.2 1.1 1.3e-35 121.6 1.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 AAL62675.1 - 9.9e-32 109.3 2.8 1.3e-31 108.9 0.9 2.0 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain AcrZ PF10766.9 AAL62678.1 - 4.6 6.9 5.3 3.7 7.2 1.1 2.6 3 0 0 3 3 3 0 Multidrug efflux pump-associated protein AcrZ Trm112p PF03966.16 AAL62682.1 - 1.9e-19 70.0 1.6 3.2e-19 69.3 1.6 1.4 1 0 0 1 1 1 1 Trm112p-like protein zf-RING_7 PF02591.15 AAL62682.1 - 0.0014 18.8 1.0 0.028 14.6 0.1 2.9 2 0 0 2 2 2 1 C4-type zinc ribbon domain zinc_ribbon_15 PF17032.5 AAL62682.1 - 0.015 16.0 1.5 0.021 15.6 1.5 1.3 1 0 0 1 1 1 0 zinc-ribbon family DUF35_N PF12172.8 AAL62682.1 - 0.07 13.0 5.8 0.48 10.4 0.0 3.0 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) NOB1_Zn_bind PF08772.11 AAL62682.1 - 0.077 13.2 0.9 0.15 12.3 0.1 1.8 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like HypA PF01155.19 AAL62682.1 - 0.11 12.5 0.8 0.2 11.7 0.8 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ribbon_3 PF13248.6 AAL62682.1 - 0.25 10.8 3.8 0.24 10.8 1.6 2.1 2 0 0 2 2 2 0 zinc-ribbon domain zf-H2C2_2 PF13465.6 AAL62682.1 - 3.9 8.1 12.2 1.5 9.4 1.8 3.4 3 0 0 3 3 3 0 Zinc-finger double domain PIN PF01850.21 AAL62683.1 - 2.1e-10 41.2 0.0 2.5e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 PIN domain PaRep2b PF07775.11 AAL62684.1 - 0.00017 20.2 0.2 0.00017 20.2 0.2 1.0 1 0 0 1 1 1 1 PaRep2b protein K1 PF02960.14 AAL62685.1 - 0.14 12.3 0.1 0.15 12.2 0.1 1.0 1 0 0 1 1 1 0 K1 glycoprotein Radical_SAM PF04055.21 AAL62686.1 - 1.2e-13 51.8 0.0 2e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily SPASM PF13186.6 AAL62686.1 - 1.1e-05 25.8 0.1 5.9e-05 23.5 0.2 2.1 1 1 1 2 2 2 1 Iron-sulfur cluster-binding domain Fer4_12 PF13353.6 AAL62686.1 - 0.00021 21.6 0.0 0.00096 19.4 0.0 1.9 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AAL62686.1 - 0.0021 18.2 0.0 0.0069 16.5 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S single cluster domain AP_endonuc_2 PF01261.24 AAL62686.1 - 0.029 13.8 0.0 0.24 10.8 0.1 2.3 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel CPBP PF02517.16 AAL62690.1 - 6.9e-16 58.4 9.3 6.9e-16 58.4 9.3 3.1 3 1 0 3 3 3 1 CPBP intramembrane metalloprotease PaRep2a PF07903.11 AAL62692.1 - 1.2e-10 41.3 0.0 1.2e-10 41.3 0.0 1.0 1 0 0 1 1 1 1 PaRep2a protein RHH_1 PF01402.21 AAL62693.1 - 3.2e-08 33.2 1.3 7.8e-08 32.0 0.5 1.9 2 0 0 2 2 2 1 Ribbon-helix-helix protein, copG family RHH_4 PF13467.6 AAL62693.1 - 3.5e-06 26.8 0.0 4.4e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Ribbon-helix-helix domain RHH_3 PF12651.7 AAL62693.1 - 7.3e-05 22.7 0.1 0.0039 17.1 0.1 2.2 2 0 0 2 2 2 1 Ribbon-helix-helix domain RHH_5 PF07878.11 AAL62693.1 - 0.0044 16.9 0.1 0.0063 16.4 0.1 1.3 1 0 0 1 1 1 1 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 MatP_C PF17414.2 AAL62693.1 - 0.019 15.1 0.0 0.028 14.6 0.0 1.2 1 0 0 1 1 1 0 MatP C-terminal ribbon-helix-helix domain CopG_antitoxin PF12441.8 AAL62693.1 - 0.081 13.5 0.0 0.16 12.5 0.0 1.5 2 0 0 2 2 2 0 CopG antitoxin of type II toxin-antitoxin system TGT PF01702.18 AAL62694.1 - 7e-05 22.1 0.0 0.0001 21.6 0.0 1.2 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase LexA_DNA_bind PF01726.16 AAL62694.1 - 0.14 12.0 0.0 0.36 10.6 0.0 1.7 1 0 0 1 1 1 0 LexA DNA binding domain PaRep2a PF07903.11 AAL62695.1 - 3.1e-61 204.6 1.5 3.7e-61 204.3 1.5 1.1 1 0 0 1 1 1 1 PaRep2a protein PaRep2b PF07775.11 AAL62696.1 - 5.9e-132 440.7 7.1 3.5e-91 306.2 0.6 2.0 1 1 1 2 2 2 2 PaRep2b protein HGD-D PF06050.13 AAL62696.1 - 0.0019 18.0 0.0 0.0029 17.4 0.0 1.3 1 0 0 1 1 1 1 2-hydroxyglutaryl-CoA dehydratase, D-component PaREP1 PF05942.11 AAL62698.1 - 2.5e-29 101.5 4.2 3e-29 101.3 4.2 1.1 1 0 0 1 1 1 1 Archaeal PaREP1/PaREP8 family L-fibroin PF05849.11 AAL62698.1 - 0.018 14.3 0.0 0.025 13.9 0.0 1.1 1 0 0 1 1 1 0 Fibroin light chain (L-fibroin) Mrr_N PF14338.6 AAL62701.1 - 1.8e-05 24.8 0.0 2.4e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Mrr N-terminal domain HTH_20 PF12840.7 AAL62701.1 - 3.7e-05 23.7 0.0 5.4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 AAL62701.1 - 7.6e-05 22.5 0.0 0.00018 21.3 0.0 1.6 1 1 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 AAL62701.1 - 0.024 14.2 0.0 0.054 13.1 0.0 1.5 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_45 PF14947.6 AAL62701.1 - 0.081 12.9 0.0 0.081 12.9 0.0 1.1 1 0 0 1 1 1 0 Winged helix-turn-helix Amidohydro_1 PF01979.20 AAL62704.1 - 2.2e-05 23.9 0.3 0.0011 18.4 0.0 2.1 1 1 0 2 2 2 2 Amidohydrolase family DUF2866 PF11065.8 AAL62705.1 - 0.059 13.4 0.1 0.14 12.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2866) DUF2283 PF10049.9 AAL62706.1 - 0.085 13.1 0.6 0.12 12.6 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2283) DUF308 PF03729.13 AAL62707.1 - 0.013 15.8 0.1 0.015 15.6 0.1 1.1 1 0 0 1 1 1 0 Short repeat of unknown function (DUF308) Phage_holin_5_2 PF16079.5 AAL62707.1 - 0.015 15.6 0.6 0.017 15.4 0.6 1.1 1 0 0 1 1 1 0 Phage holin family Hol44, in holin superfamily V DUF979 PF06166.12 AAL62708.1 - 0.00052 19.3 0.8 0.00066 18.9 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF979) DUF996 PF06195.13 AAL62708.1 - 0.0088 16.3 15.9 0.66 10.3 3.8 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF996) DUF373 PF04123.13 AAL62708.1 - 0.35 10.3 8.0 0.52 9.7 8.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) ABC_tran PF00005.27 AAL62709.1 - 1.5e-27 96.8 0.0 2.1e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAL62709.1 - 1.2e-13 51.6 0.4 7.4e-09 35.8 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system MeaB PF03308.16 AAL62709.1 - 0.0014 17.7 0.3 0.0029 16.6 0.3 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 AAL62709.1 - 0.0031 17.8 0.1 0.14 12.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AAL62709.1 - 0.0055 17.1 0.0 0.013 15.9 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 AAL62709.1 - 0.0081 15.6 0.1 2.9 7.2 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAL62709.1 - 0.01 15.6 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 AAL62709.1 - 0.011 16.3 0.0 0.017 15.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 AAL62709.1 - 0.015 15.8 0.1 0.069 13.6 0.0 2.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 AAL62709.1 - 0.023 14.4 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 AAL62709.1 - 0.025 14.5 0.0 0.059 13.3 0.0 1.6 2 0 0 2 2 2 0 Rad17 P-loop domain NTPase_1 PF03266.15 AAL62709.1 - 0.06 13.2 0.9 0.41 10.5 0.0 2.6 2 1 1 3 3 3 0 NTPase HTH_11 PF08279.12 AAL62709.1 - 0.092 12.7 0.0 0.28 11.2 0.0 1.8 1 0 0 1 1 1 0 HTH domain KAP_NTPase PF07693.14 AAL62709.1 - 0.093 12.0 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain DUF87 PF01935.17 AAL62709.1 - 0.099 12.7 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain cobW PF02492.19 AAL62709.1 - 0.1 12.2 0.1 0.18 11.4 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 AAL62709.1 - 0.12 12.1 0.0 0.39 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 AAL62709.1 - 0.13 12.5 0.0 0.22 11.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain MobB PF03205.14 AAL62709.1 - 0.15 12.0 0.3 0.49 10.3 0.1 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 AAL62709.1 - 0.15 12.6 0.0 0.32 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 AAL62709.1 - 0.18 11.3 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 AAL62709.1 - 0.21 10.8 0.2 0.77 8.9 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain ABC2_membrane PF01061.24 AAL62710.1 - 0.00025 20.5 20.8 0.00025 20.5 20.8 1.4 2 0 0 2 2 2 1 ABC-2 type transporter QueF PF14489.6 AAL62711.1 - 2.6e-08 33.9 0.1 3.5e-08 33.5 0.1 1.2 1 0 0 1 1 1 1 QueF-like protein GTP_cyclohydroI PF01227.22 AAL62711.1 - 4.5e-07 29.4 0.1 5.3e-07 29.2 0.1 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I IF3_C PF00707.22 AAL62711.1 - 0.0034 17.3 0.0 0.0049 16.8 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain Alpha-amylase PF00128.24 AAL62712.1 - 1.2e-25 90.9 0.0 1.3e-22 80.9 0.0 2.9 1 1 0 1 1 1 1 Alpha amylase, catalytic domain ATPase PF06745.13 AAL62713.1 - 2.8e-17 62.8 0.0 2e-15 56.8 0.0 2.4 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 AAL62713.1 - 6.6e-08 32.3 0.0 1.3e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 AAL62713.1 - 1.2e-05 25.1 0.0 2.6e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 AAL62713.1 - 2.1e-05 24.3 0.0 0.00017 21.4 0.0 2.2 2 1 0 2 2 2 1 IstB-like ATP binding protein GvpD PF07088.11 AAL62713.1 - 0.0001 21.1 0.0 0.012 14.2 0.0 2.1 1 1 0 1 1 1 1 GvpD gas vesicle protein AAA PF00004.29 AAL62713.1 - 0.00018 21.9 0.0 0.0015 19.0 0.0 2.1 1 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AAL62713.1 - 0.00076 19.8 0.0 0.0012 19.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 AAL62713.1 - 0.0011 18.4 0.0 0.0029 17.0 0.0 1.6 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain ATPase_2 PF01637.18 AAL62713.1 - 0.0067 16.4 0.0 0.017 15.1 0.0 1.7 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea ABC_tran PF00005.27 AAL62713.1 - 0.0076 16.8 0.0 0.015 15.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_30 PF13604.6 AAL62713.1 - 0.013 15.3 0.2 0.032 13.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 AAL62713.1 - 0.013 14.7 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.22 AAL62713.1 - 0.015 14.5 0.0 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 AAL62713.1 - 0.016 15.6 0.0 0.099 13.0 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.23 AAL62713.1 - 0.025 14.7 0.0 0.05 13.7 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase NACHT PF05729.12 AAL62713.1 - 0.044 13.7 0.0 0.092 12.7 0.0 1.6 1 1 0 1 1 1 0 NACHT domain AAA_13 PF13166.6 AAL62713.1 - 0.05 12.2 0.0 0.064 11.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 AAL62713.1 - 0.11 12.9 0.0 0.37 11.2 0.0 1.9 2 1 0 2 2 2 0 RNA helicase AAA_23 PF13476.6 AAL62713.1 - 0.14 12.6 0.0 0.25 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rad51 PF08423.11 AAL62713.1 - 0.16 11.2 0.2 1.5 8.0 0.2 2.1 1 1 0 1 1 1 0 Rad51 AAA_5 PF07728.14 AAL62713.1 - 0.16 11.9 0.0 0.52 10.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) TniB PF05621.11 AAL62713.1 - 0.19 11.1 0.0 2.1 7.7 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein Amidohydro_1 PF01979.20 AAL62714.1 - 2.7e-11 43.4 0.0 6.6e-11 42.1 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase family Gate PF07670.14 AAL62715.1 - 1.2e-23 83.5 14.7 1.8e-20 73.3 4.2 4.0 4 1 1 5 5 5 2 Nucleoside recognition FeoB_N PF02421.18 AAL62715.1 - 0.061 12.9 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B FeoB_N PF02421.18 AAL62716.1 - 3.3e-18 65.7 0.0 3.8e-18 65.5 0.0 1.0 1 0 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 AAL62716.1 - 4.9e-17 62.0 0.0 5.8e-17 61.8 0.0 1.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 AAL62716.1 - 0.033 14.0 0.0 0.033 14.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system SRPRB PF09439.10 AAL62716.1 - 0.082 12.3 0.0 0.28 10.6 0.0 1.7 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.6 AAL62716.1 - 0.094 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 AAL62717.1 - 4e-36 124.6 0.0 5.5e-36 124.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAL62717.1 - 6.2e-11 42.7 1.0 0.00011 22.1 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AAL62717.1 - 0.00025 20.7 0.1 0.00043 20.0 0.1 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 AAL62717.1 - 0.00089 18.8 0.0 0.76 9.2 0.1 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AAL62717.1 - 0.001 19.5 0.0 0.0014 19.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 AAL62717.1 - 0.0099 15.6 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 AAL62717.1 - 0.013 15.5 0.0 0.055 13.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 AAL62717.1 - 0.015 15.7 0.0 0.081 13.4 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 AAL62717.1 - 0.025 15.1 0.1 0.034 14.6 0.1 1.1 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AAL62717.1 - 0.026 14.8 0.1 0.038 14.2 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AAL62717.1 - 0.032 14.4 0.0 0.053 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 AAL62717.1 - 0.04 13.8 0.2 0.062 13.2 0.2 1.2 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 AAL62717.1 - 0.042 13.9 0.1 0.068 13.3 0.1 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 AAL62717.1 - 0.055 12.7 0.0 0.096 12.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 AAL62717.1 - 0.06 13.3 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 NACHT domain Cytidylate_kin PF02224.18 AAL62717.1 - 0.12 12.1 0.2 0.2 11.4 0.2 1.3 1 0 0 1 1 1 0 Cytidylate kinase DUF87 PF01935.17 AAL62717.1 - 0.13 12.4 0.1 0.22 11.6 0.1 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain ATP-synt_ab PF00006.25 AAL62717.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.6 AAL62717.1 - 0.15 11.8 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AAL62717.1 - 0.16 12.6 0.2 0.25 11.9 0.2 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 AAL62717.1 - 0.25 10.9 0.0 0.42 10.2 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SBP_bac_6 PF13343.6 AAL62719.1 - 5.3e-19 68.6 0.0 1.2e-18 67.5 0.0 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AAL62719.1 - 7.8e-17 62.2 0.5 1.2e-16 61.6 0.5 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 AAL62719.1 - 1.8e-16 60.8 0.0 3e-16 60.1 0.0 1.3 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 AAL62719.1 - 9.7e-13 48.4 0.0 3e-12 46.8 0.0 1.8 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein TraE PF05309.11 AAL62719.1 - 0.13 11.7 0.4 0.18 11.2 0.4 1.2 1 0 0 1 1 1 0 TraE protein GTP_EFTU PF00009.27 AAL62720.1 - 2.3e-57 193.7 0.0 3.4e-57 193.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 AAL62720.1 - 1.4e-29 102.3 0.0 4.5e-29 100.7 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 AAL62720.1 - 9.8e-23 80.0 0.1 2e-22 79.0 0.1 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 AAL62720.1 - 4.6e-20 71.4 0.0 1.3e-19 70.0 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 AAL62720.1 - 1.3e-15 57.5 0.2 3e-15 56.4 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 AAL62720.1 - 0.028 14.5 0.0 0.061 13.4 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase RF3_C PF16658.5 AAL62720.1 - 0.084 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain ThiC_Rad_SAM PF01964.18 AAL62721.1 - 7e-165 548.8 0.0 8.3e-165 548.6 0.0 1.0 1 0 0 1 1 1 1 Radical SAM ThiC family Met_asp_mut_E PF06368.11 AAL62721.1 - 0.12 10.8 0.0 0.19 10.2 0.0 1.2 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) PUA PF01472.20 AAL62721.1 - 0.36 10.8 4.0 0.44 10.5 0.1 2.8 3 0 0 3 3 3 0 PUA domain PIN PF01850.21 AAL62723.1 - 2.2e-11 44.3 2.1 5.2e-11 43.1 2.1 1.5 1 1 0 1 1 1 1 PIN domain CbiG_N PF11760.8 AAL62725.1 - 1.5e-25 89.0 1.6 2.3e-25 88.4 0.1 2.1 3 0 0 3 3 3 1 Cobalamin synthesis G N-terminal CbiG_C PF01890.16 AAL62725.1 - 1.5e-16 61.0 0.8 2.4e-16 60.3 0.1 1.7 2 0 0 2 2 2 1 Cobalamin synthesis G C-terminus HTH_AsnC-type PF13404.6 AAL62725.1 - 0.021 14.6 1.1 24 4.8 0.1 3.4 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain TP_methylase PF00590.20 AAL62726.1 - 3.1e-32 112.2 0.0 3.6e-32 112.0 0.0 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Peptidase_S24 PF00717.23 AAL62726.1 - 0.042 13.8 0.0 0.092 12.7 0.0 1.6 1 0 0 1 1 1 0 Peptidase S24-like B12-binding PF02310.19 AAL62726.1 - 0.084 12.9 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 B12 binding domain Peripla_BP_6 PF13458.6 AAL62726.1 - 0.16 11.6 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein MCM PF00493.23 AAL62726.1 - 0.17 11.0 0.0 0.24 10.5 0.0 1.1 1 0 0 1 1 1 0 MCM P-loop domain CbtB PF09489.10 AAL62727.1 - 5.5e-05 23.2 3.0 0.00023 21.2 3.0 2.0 1 1 0 1 1 1 1 Probable cobalt transporter subunit (CbtB) DUF4203 PF13886.6 AAL62728.1 - 0.0046 16.6 5.0 0.0064 16.2 5.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) CbiC PF02570.15 AAL62729.1 - 3.5e-44 150.8 0.0 8.7e-44 149.5 0.1 1.6 2 0 0 2 2 2 1 Precorrin-8X methylmutase CbiX PF01903.17 AAL62729.1 - 8.5e-16 58.2 0.0 2e-15 57.0 0.0 1.6 2 0 0 2 2 2 1 CbiX TP_methylase PF00590.20 AAL62730.1 - 1.1e-36 126.8 2.3 1.3e-36 126.6 2.3 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases CbiD PF01888.17 AAL62731.1 - 2.7e-75 252.9 0.8 4e-75 252.4 0.8 1.2 1 0 0 1 1 1 1 CbiD Methyltransf_31 PF13847.6 AAL62732.1 - 1.6e-10 41.0 0.0 2.5e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 AAL62732.1 - 2.2e-09 37.1 0.0 3e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_3 PF01596.17 AAL62732.1 - 2.5e-08 33.4 0.1 5.8e-07 28.9 0.1 2.0 1 1 1 2 2 2 2 O-methyltransferase UPF0020 PF01170.18 AAL62732.1 - 1.2e-07 31.6 0.4 1.9e-06 27.7 0.4 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 MTS PF05175.14 AAL62732.1 - 2.1e-07 30.6 0.0 3.2e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 AAL62732.1 - 6.7e-07 29.9 0.0 1.3e-06 29.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 AAL62732.1 - 1.8e-06 27.8 0.1 2.8e-06 27.3 0.1 1.3 1 1 1 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.15 AAL62732.1 - 2.6e-06 27.2 0.0 3.6e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_15 PF09445.10 AAL62732.1 - 2.8e-06 27.0 0.0 3.6e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 AAL62732.1 - 4.3e-05 23.3 0.0 4.9e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_23 PF13489.6 AAL62732.1 - 0.00032 20.6 0.0 0.0008 19.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 AAL62732.1 - 0.00033 20.0 0.1 0.0004 19.8 0.1 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 AAL62732.1 - 0.00037 20.5 0.0 0.0006 19.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAL62732.1 - 0.00085 19.9 0.0 0.0016 19.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 AAL62732.1 - 0.0021 19.0 0.0 0.0035 18.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AAL62732.1 - 0.011 15.1 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 AAL62732.1 - 0.016 15.2 0.0 0.02 14.9 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 AAL62732.1 - 0.02 15.6 0.0 0.034 14.9 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 AAL62732.1 - 0.08 13.0 0.0 0.41 10.8 0.0 1.8 2 0 0 2 2 2 0 FtsJ-like methyltransferase TRM PF02005.16 AAL62732.1 - 0.15 11.2 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase TP_methylase PF00590.20 AAL62733.1 - 3.5e-32 112.1 0.1 4.3e-32 111.8 0.1 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases RTTN_N PF14726.6 AAL62733.1 - 0.15 12.9 0.0 0.36 11.7 0.0 1.6 1 0 0 1 1 1 0 Rotatin, an armadillo repeat protein, centriole functioning TP_methylase PF00590.20 AAL62734.1 - 1.3e-48 165.8 3.8 1.3e-48 165.8 3.8 1.7 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF5612 PF18462.1 AAL62734.1 - 0.02 14.7 2.0 1.5 8.6 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5612) Erv26 PF04148.13 AAL62735.1 - 0.037 13.9 4.7 0.043 13.6 4.7 1.1 1 0 0 1 1 1 0 Transmembrane adaptor Erv26 RAMP PF04901.13 AAL62735.1 - 0.62 10.1 2.8 0.31 11.0 0.5 1.6 1 1 1 2 2 2 0 Receptor activity modifying family Phage_holin_3_6 PF07332.11 AAL62736.1 - 0.14 12.2 7.3 0.04 14.0 4.6 1.4 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III PDDEXK_10 PF07788.11 AAL62737.1 - 4.3e-32 109.9 2.2 9.1e-32 108.8 2.2 1.6 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily DUF3782 PF12644.7 AAL62737.1 - 2.5e-26 91.6 1.1 4.3e-26 90.9 1.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3782) ScsC_N PF18312.1 AAL62737.1 - 0.0098 15.7 4.2 0.18 11.7 0.5 3.1 2 1 1 3 3 3 2 Copper resistance protein ScsC N-terminal domain Peptidase_S24 PF00717.23 AAL62737.1 - 0.049 13.6 0.1 0.13 12.2 0.1 1.6 1 1 0 1 1 1 0 Peptidase S24-like DUF3618 PF12277.8 AAL62737.1 - 0.075 13.3 0.2 0.17 12.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3618) ATPase_2 PF01637.18 AAL62738.1 - 3.3e-62 210.4 0.0 4.1e-62 210.1 0.0 1.1 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 AAL62738.1 - 0.0025 18.2 0.0 0.004 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 AAL62738.1 - 0.0033 17.6 0.0 0.0056 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AAL62738.1 - 0.0042 17.4 0.0 0.008 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 AAL62738.1 - 0.013 15.9 0.0 0.02 15.3 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 AAL62738.1 - 0.014 15.1 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 AAL62738.1 - 0.071 13.0 0.0 0.32 10.9 0.0 2.0 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.27 AAL62739.1 - 2.4e-21 76.7 0.1 1.1e-20 74.6 0.1 1.9 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAL62739.1 - 3.9e-15 56.5 0.5 6.5e-07 29.5 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAL62739.1 - 3.2e-10 39.8 0.0 0.00018 21.0 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 AAL62739.1 - 6.7e-08 32.6 0.0 8.7e-05 22.4 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 AAL62739.1 - 4.7e-06 27.2 0.0 7.2e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AAL62739.1 - 0.00021 21.5 0.0 0.0013 18.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAL62739.1 - 0.00037 20.2 0.1 0.0009 18.9 0.1 1.6 2 0 0 2 2 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 AAL62739.1 - 0.00048 19.9 0.1 0.00093 19.0 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AAL62739.1 - 0.00051 20.3 0.2 0.0009 19.5 0.2 1.7 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 AAL62739.1 - 0.00064 18.6 0.1 0.017 13.9 0.0 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class SbcCD_C PF13558.6 AAL62739.1 - 0.0011 19.2 0.0 0.0081 16.4 0.0 2.1 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 AAL62739.1 - 0.0013 19.1 0.1 0.0031 17.9 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 AAL62739.1 - 0.0028 18.2 0.1 0.1 13.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain DUF3584 PF12128.8 AAL62739.1 - 0.0055 14.3 0.1 0.0074 13.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA PF00004.29 AAL62739.1 - 0.0059 17.0 0.1 0.014 15.8 0.1 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 AAL62739.1 - 0.0066 16.1 0.1 0.013 15.2 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain IstB_IS21 PF01695.17 AAL62739.1 - 0.011 15.4 0.0 3.2 7.4 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein NACHT PF05729.12 AAL62739.1 - 0.012 15.5 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 AAL62739.1 - 0.013 15.5 0.1 0.049 13.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 AAL62739.1 - 0.019 15.0 0.0 0.15 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 AAL62739.1 - 0.02 14.5 0.3 0.037 13.6 0.1 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 AAL62739.1 - 0.023 14.3 0.9 0.11 12.1 0.1 2.1 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 AAL62739.1 - 0.03 14.6 0.1 0.064 13.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 AAL62739.1 - 0.043 13.2 0.0 3.3 7.1 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 AAL62739.1 - 0.056 13.8 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 AAL62739.1 - 0.057 13.3 0.1 2.5 8.0 0.1 2.2 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.6 AAL62739.1 - 0.073 12.8 0.1 0.16 11.6 0.1 1.6 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 AAL62739.1 - 0.091 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_13 PF13166.6 AAL62739.1 - 0.1 11.2 0.0 0.66 8.5 0.1 1.8 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 AAL62739.1 - 0.11 12.2 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein T2SSE PF00437.20 AAL62739.1 - 0.11 11.5 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase_2 PF01637.18 AAL62739.1 - 0.16 11.9 0.1 0.33 10.9 0.1 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea PrpR_N PF06506.11 AAL62739.1 - 0.19 11.3 0.0 0.75 9.4 0.0 1.8 2 0 0 2 2 2 0 Propionate catabolism activator Rad17 PF03215.15 AAL62739.1 - 0.22 11.4 0.1 0.64 9.9 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain PaRep2b PF07775.11 AAL62740.1 - 2e-277 920.7 11.5 2.2e-277 920.5 11.5 1.0 1 0 0 1 1 1 1 PaRep2b protein PASTA PF03793.19 AAL62740.1 - 0.0018 18.1 1.5 0.79 9.6 0.0 3.4 2 1 1 3 3 3 1 PASTA domain SPOR PF05036.13 AAL62740.1 - 0.019 15.4 1.2 1.5 9.3 0.0 3.2 3 0 0 3 3 3 0 Sporulation related domain PEGA PF08308.11 AAL62740.1 - 0.14 12.1 0.3 0.46 10.4 0.3 1.9 1 0 0 1 1 1 0 PEGA domain Glyco_hydro_36C PF16874.5 AAL62740.1 - 0.17 12.4 1.0 2 9.0 0.1 3.2 2 1 1 3 3 3 0 Glycosyl hydrolase family 36 C-terminal domain PaRep2a PF07903.11 AAL62741.1 - 9.4e-20 70.7 0.0 9.9e-20 70.6 0.0 1.0 1 0 0 1 1 1 1 PaRep2a protein FecCD PF01032.18 AAL62742.1 - 3e-60 203.8 34.5 4e-60 203.4 34.5 1.1 1 0 0 1 1 1 1 FecCD transport family BPD_transp_2 PF02653.16 AAL62742.1 - 0.014 14.5 2.0 0.014 14.5 2.0 3.1 2 1 2 4 4 4 0 Branched-chain amino acid transport system / permease component Peripla_BP_2 PF01497.18 AAL62743.1 - 6.8e-23 81.5 0.0 9.9e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein COG2 PF06148.11 AAL62743.1 - 0.0062 16.6 0.1 0.011 15.8 0.1 1.3 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Baculo_PEP_C PF04513.12 AAL62743.1 - 0.018 15.1 0.3 0.037 14.1 0.3 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus COG5 PF10392.9 AAL62743.1 - 0.022 14.9 0.4 0.039 14.1 0.4 1.3 1 0 0 1 1 1 0 Golgi transport complex subunit 5 CENP-Q PF13094.6 AAL62743.1 - 0.024 14.8 0.5 0.038 14.2 0.5 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit ATG16 PF08614.11 AAL62743.1 - 0.033 14.4 0.1 0.05 13.8 0.1 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) RPW8 PF05659.11 AAL62743.1 - 0.04 13.6 0.1 0.071 12.8 0.1 1.3 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 TMF_DNA_bd PF12329.8 AAL62743.1 - 0.059 13.4 0.6 0.12 12.4 0.6 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding MPS2 PF17060.5 AAL62743.1 - 0.073 12.3 0.1 0.11 11.8 0.1 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 HrpB7 PF09486.10 AAL62743.1 - 0.087 13.2 0.5 0.14 12.6 0.5 1.2 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) ADIP PF11559.8 AAL62743.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding CENP-H PF05837.12 AAL62743.1 - 0.17 12.3 0.1 0.26 11.7 0.1 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Spc7 PF08317.11 AAL62743.1 - 0.19 10.6 0.0 0.27 10.1 0.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein TolA_bind_tri PF16331.5 AAL62743.1 - 0.28 11.3 2.1 0.59 10.3 2.1 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation Cep57_CLD_2 PF14197.6 AAL62743.1 - 0.4 10.8 2.1 1.6 8.9 0.1 2.4 2 1 0 2 2 1 0 Centrosome localisation domain of PPC89 Peptidase_M16 PF00675.20 AAL62744.1 - 1.3e-17 64.2 0.0 1.9e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 AAL62744.1 - 8e-08 32.5 0.0 1.5e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain NTP_transf_3 PF12804.7 AAL62745.1 - 1.4e-14 54.8 0.0 1.7e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF1015 PF06245.11 AAL62745.1 - 0.044 12.6 0.0 4.6 6.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1015) DUF5043 PF16446.5 AAL62745.1 - 0.053 13.5 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5043) CTP_transf_3 PF02348.19 AAL62745.1 - 0.056 13.4 0.0 0.17 11.8 0.0 1.7 2 0 0 2 2 2 0 Cytidylyltransferase ParBc PF02195.18 AAL62745.1 - 0.07 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 ParB-like nuclease domain CobA_CobO_BtuR PF02572.15 AAL62746.1 - 5.2e-29 101.7 0.8 1.4e-27 97.0 0.8 2.0 1 1 0 1 1 1 1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP IstB_IS21 PF01695.17 AAL62746.1 - 0.16 11.7 1.4 4 7.1 1.4 2.1 1 1 0 1 1 1 0 IstB-like ATP binding protein Herpes_ori_bp PF02399.15 AAL62746.1 - 0.24 9.4 0.0 0.32 9.0 0.0 1.1 1 0 0 1 1 1 0 Origin of replication binding protein CbiZ PF01955.18 AAL62747.1 - 5.9e-29 101.5 0.2 1.5e-28 100.2 0.2 1.7 1 1 0 1 1 1 1 Adenosylcobinamide amidohydrolase Diphthami_syn_2 PF01902.17 AAL62749.1 - 7.1e-19 68.2 0.0 9e-19 67.8 0.0 1.1 1 0 0 1 1 1 1 Diphthamide synthase DUF460 PF04312.13 AAL62749.1 - 0.16 11.6 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF460) Asn_synthase PF00733.21 AAL62750.1 - 7.9e-21 75.1 0.0 3e-14 53.4 0.0 2.0 2 0 0 2 2 2 2 Asparagine synthase QueC PF06508.13 AAL62750.1 - 0.0019 17.8 0.0 0.005 16.4 0.0 1.6 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Aminotran_1_2 PF00155.21 AAL62751.1 - 5.6e-20 71.8 0.0 5.4e-19 68.6 0.0 2.4 1 1 0 1 1 1 1 Aminotransferase class I and II CobS PF02654.15 AAL62752.1 - 3.5e-32 112.3 10.1 4e-32 112.1 10.1 1.0 1 0 0 1 1 1 1 Cobalamin-5-phosphate synthase CobD_Cbib PF03186.13 AAL62753.1 - 3e-44 151.3 0.4 4.4e-44 150.8 0.4 1.3 1 0 0 1 1 1 1 CobD/Cbib protein MarR PF01047.22 AAL62755.1 - 1.9e-06 27.7 0.1 5.1e-06 26.3 0.1 1.7 2 0 0 2 2 2 1 MarR family HTH_5 PF01022.20 AAL62755.1 - 3e-06 27.0 0.0 4.7e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 AAL62755.1 - 2.8e-05 23.6 0.0 4.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Penicillinase_R PF03965.16 AAL62755.1 - 4.1e-05 23.9 0.1 4.8e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Penicillinase repressor HTH_20 PF12840.7 AAL62755.1 - 0.0001 22.3 0.1 0.00024 21.1 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain TrmB PF01978.19 AAL62755.1 - 0.00019 21.3 0.0 0.00029 20.6 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HxlR PF01638.17 AAL62755.1 - 0.0011 18.8 0.2 0.0012 18.6 0.2 1.2 1 0 0 1 1 1 1 HxlR-like helix-turn-helix MarR_2 PF12802.7 AAL62755.1 - 0.0029 17.4 0.4 0.0058 16.5 0.1 1.5 1 1 0 1 1 1 1 MarR family HTH_CodY PF08222.11 AAL62755.1 - 0.017 14.7 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 CodY helix-turn-helix domain Rrf2 PF02082.20 AAL62755.1 - 0.022 15.1 0.1 0.029 14.7 0.1 1.3 1 0 0 1 1 1 0 Transcriptional regulator DUF4763 PF15960.5 AAL62755.1 - 0.037 13.3 0.2 0.042 13.2 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) HTH_28 PF13518.6 AAL62755.1 - 0.051 13.7 0.3 0.1 12.8 0.2 1.5 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_27 PF13463.6 AAL62755.1 - 0.099 13.1 0.1 0.17 12.4 0.1 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain Oxidored_molyb PF00174.19 AAL62757.1 - 1.8e-31 109.0 0.0 2.4e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Inhibitor_I67 PF11405.8 AAL62757.1 - 0.15 12.4 0.1 0.25 11.6 0.1 1.4 1 0 0 1 1 1 0 Bromelain inhibitor VI UPF0175 PF03683.13 AAL62760.1 - 0.0076 15.9 0.1 0.063 13.0 0.0 2.3 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0175) DUF1918 PF08940.11 AAL62761.1 - 0.0098 15.5 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1918) NTP_transf_2 PF01909.23 AAL62766.1 - 1.8e-05 24.9 0.1 4.6e-05 23.6 0.1 1.8 1 1 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 AAL62766.1 - 0.085 13.0 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase ATPase_2 PF01637.18 AAL62767.1 - 1.5e-63 214.8 0.0 2.3e-63 214.2 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_33 PF13671.6 AAL62767.1 - 0.0076 16.4 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAL62767.1 - 0.013 15.9 0.7 0.041 14.3 0.2 2.1 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 AAL62767.1 - 0.02 15.1 0.0 0.036 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AAL62767.1 - 0.08 12.7 0.0 0.19 11.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain SieB PF14163.6 AAL62767.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Super-infection exclusion protein B AAA_30 PF13604.6 AAL62767.1 - 0.15 11.8 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 AAL62767.1 - 0.15 12.4 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ChaC PF04752.12 AAL62767.1 - 0.17 12.0 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 ChaC-like protein ATPase_2 PF01637.18 AAL62768.1 - 7.5e-64 215.8 0.0 9.1e-64 215.5 0.0 1.1 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA PF00004.29 AAL62768.1 - 0.0022 18.4 0.0 0.0044 17.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 AAL62768.1 - 0.0064 16.2 0.0 0.0098 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AAL62768.1 - 0.0067 16.7 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AAL62768.1 - 0.008 16.3 0.0 0.016 15.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAL62768.1 - 0.027 14.9 0.2 0.06 13.7 0.1 1.7 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.22 AAL62768.1 - 0.16 12.3 0.0 0.28 11.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 AAL62768.1 - 0.18 11.7 0.2 0.8 9.6 0.2 2.0 1 1 0 1 1 1 0 NACHT domain AAA_14 PF13173.6 AAL62768.1 - 0.2 11.7 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain PaREP1 PF05942.11 AAL62769.1 - 1.6e-26 92.5 2.9 1.7e-26 92.4 2.9 1.0 1 0 0 1 1 1 1 Archaeal PaREP1/PaREP8 family HEPN PF05168.14 AAL62769.1 - 0.025 14.7 0.5 0.037 14.2 0.5 1.3 1 0 0 1 1 1 0 HEPN domain ParE_toxin PF05016.15 AAL62769.1 - 0.061 13.9 0.5 0.072 13.7 0.5 1.3 1 1 0 1 1 1 0 ParE toxin of type II toxin-antitoxin system, parDE Gpi16 PF04113.14 AAL62769.1 - 0.12 10.8 0.0 0.12 10.7 0.0 1.0 1 0 0 1 1 1 0 Gpi16 subunit, GPI transamidase component Pox_E2-like PF04497.12 AAL62774.1 - 0.061 11.8 0.1 0.081 11.4 0.1 1.1 1 0 0 1 1 1 0 Poxviridae protein PaREP1 PF05942.11 AAL62776.1 - 3.6e-31 107.5 0.5 3.6e-31 107.5 0.5 1.6 2 0 0 2 2 2 1 Archaeal PaREP1/PaREP8 family Glycos_transf_2 PF00535.26 AAL62778.1 - 2.4e-36 125.1 0.0 3.4e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAL62778.1 - 1.6e-23 83.8 0.9 1e-22 81.2 0.9 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 AAL62778.1 - 1.1e-15 57.5 0.8 8.1e-15 54.7 0.0 2.5 3 0 0 3 3 3 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 AAL62778.1 - 4.1e-15 56.2 0.5 2.1e-14 53.9 0.2 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_2 PF10111.9 AAL62778.1 - 2e-10 40.6 0.0 3.7e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 YAcAr PF10686.9 AAL62778.1 - 1.2e-05 25.2 0.0 3.4e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 YspA, cpYpsA-related SLOG family Glyco_tranf_2_4 PF13704.6 AAL62778.1 - 0.0029 18.1 0.0 0.0074 16.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 TniB PF05621.11 AAL62778.1 - 0.073 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein DUF2283 PF10049.9 AAL62779.1 - 2.1e-07 31.1 0.2 2.4e-07 30.8 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2283) ATP-grasp PF02222.22 AAL62779.1 - 0.082 12.5 0.0 0.082 12.5 0.0 1.0 1 0 0 1 1 1 0 ATP-grasp domain PaREP1 PF05942.11 AAL62780.1 - 1.1e-30 105.9 2.5 1.7e-30 105.3 2.5 1.3 1 0 0 1 1 1 1 Archaeal PaREP1/PaREP8 family ATPase_2 PF01637.18 AAL62781.1 - 1.3e-61 208.5 0.0 1.9e-61 208.0 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_30 PF13604.6 AAL62781.1 - 0.0037 17.0 0.0 0.0075 16.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAL62781.1 - 0.0042 17.5 0.0 0.0095 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AAL62781.1 - 0.011 16.0 0.0 0.019 15.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AAL62781.1 - 0.031 14.4 0.0 0.054 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 AAL62781.1 - 0.073 13.5 0.0 0.15 12.5 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 AAL62781.1 - 0.14 12.2 0.0 0.33 11.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 AAL62781.1 - 0.16 11.1 0.0 0.46 9.6 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF815) SRP54 PF00448.22 AAL62781.1 - 0.16 11.6 0.0 14 5.2 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain BrnT_toxin PF04365.13 AAL62783.1 - 0.017 15.4 0.0 0.025 14.9 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system DUF4258 PF14076.6 AAL62783.1 - 0.071 13.5 0.3 0.2 12.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4258) DUF2283 PF10049.9 AAL62784.1 - 4.1e-19 68.5 1.1 5e-19 68.3 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2283) Glyco_transf_4 PF13439.6 AAL62785.1 - 1.4e-30 106.5 6.7 3.7e-30 105.2 6.1 1.9 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AAL62785.1 - 4.7e-20 72.6 12.7 4.7e-20 72.6 12.7 2.1 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 AAL62785.1 - 6e-12 46.2 0.2 8.8e-10 39.1 0.1 2.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AAL62785.1 - 2.3e-10 40.3 0.0 7.6e-10 38.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 AAL62785.1 - 1.6e-06 28.0 1.1 4.6e-05 23.2 0.2 2.4 1 1 1 2 2 2 1 Starch synthase catalytic domain Glyco_transf_28 PF03033.20 AAL62785.1 - 0.015 15.4 0.2 0.52 10.4 0.0 2.4 2 0 0 2 2 2 0 Glycosyltransferase family 28 N-terminal domain Glyco_trans_4_2 PF13477.6 AAL62785.1 - 0.016 15.2 0.0 0.03 14.3 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase 4-like AP_endonuc_2 PF01261.24 AAL62785.1 - 0.036 13.5 0.2 0.21 11.0 0.0 2.1 1 1 0 2 2 2 0 Xylose isomerase-like TIM barrel XdhC_C PF13478.6 AAL62785.1 - 0.043 14.3 0.6 3 8.4 0.1 2.5 2 1 0 2 2 2 0 XdhC Rossmann domain MeaB PF03308.16 AAL62785.1 - 0.11 11.4 0.0 13 4.7 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Glyco_trans_1_4 PF13692.6 AAL62786.1 - 1e-12 48.6 0.3 1.5e-10 41.7 0.0 2.8 2 1 1 3 3 3 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAL62786.1 - 6.8e-11 42.5 4.0 6.8e-11 42.5 4.0 2.2 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 AAL62786.1 - 2.5e-10 40.1 0.0 8.4e-10 38.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 AAL62786.1 - 3.1e-07 31.0 6.7 3.1e-07 31.0 6.7 2.3 2 0 0 2 2 2 2 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 AAL62786.1 - 0.0017 18.7 0.0 0.015 15.7 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 DUF1897 PF09005.10 AAL62789.1 - 0.099 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1897) GPI2 PF06432.11 AAL62791.1 - 1.2 8.5 6.7 0.15 11.5 1.6 2.2 2 2 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase Glycos_transf_2 PF00535.26 AAL62792.1 - 3.1e-20 72.7 0.0 5.1e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAL62792.1 - 3.1e-06 27.3 0.0 5.2e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AAL62792.1 - 1.4e-05 25.5 0.0 4.2e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 Peptidase_A8 PF01252.18 AAL62792.1 - 1 9.6 3.1 2.8 8.2 0.2 2.1 2 0 0 2 2 2 0 Signal peptidase (SPase) II Phage_holin_3_6 PF07332.11 AAL62792.1 - 5.4 7.1 16.1 10 6.2 2.7 2.5 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Glycos_transf_2 PF00535.26 AAL62794.1 - 1.8e-24 86.4 0.0 4.4e-24 85.2 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAL62794.1 - 4.5e-08 33.3 0.0 8.3e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 AAL62794.1 - 0.00027 20.5 0.0 0.00085 18.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 UvrC_HhH_N PF08459.11 AAL62794.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal Glycos_transf_1 PF00534.20 AAL62795.1 - 3.1e-39 134.3 0.0 4.7e-39 133.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAL62795.1 - 1.4e-27 96.7 0.0 2.3e-27 96.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAL62795.1 - 9.9e-23 81.0 0.6 2.1e-22 79.9 0.6 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AAL62795.1 - 1.2e-12 48.5 0.0 6.7e-12 46.1 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 AAL62795.1 - 4.8e-09 36.5 0.0 1.1e-08 35.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_2 PF00535.26 AAL62796.1 - 1.4e-30 106.3 0.3 2.3e-30 105.7 0.1 1.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAL62796.1 - 1.2e-15 58.0 0.0 2e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 AAL62796.1 - 5.5e-11 42.4 0.4 2e-10 40.6 0.1 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 AAL62796.1 - 0.00016 21.6 0.1 0.0072 16.3 0.1 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_4 PF13704.6 AAL62796.1 - 0.00096 19.6 0.0 0.0027 18.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Anp1 PF03452.14 AAL62796.1 - 0.0045 16.5 0.0 0.007 15.8 0.0 1.3 1 0 0 1 1 1 1 Anp1 Glyco_tranf_2_5 PF13712.6 AAL62796.1 - 0.0068 16.1 0.0 0.015 15.0 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family Glyco_transf_4 PF13439.6 AAL62797.1 - 4e-14 53.0 0.0 8.3e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 AAL62797.1 - 2.6e-11 43.4 0.1 5.6e-11 42.3 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAL62797.1 - 9.1e-07 29.4 0.0 2.1e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 AAL62797.1 - 6.6e-05 23.4 0.0 9.4e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 AAL62797.1 - 0.015 15.3 0.7 0.058 13.4 0.1 2.1 2 0 0 2 2 2 0 Glycosyl transferase 4-like Polysacc_synt_3 PF13440.6 AAL62797.1 - 0.15 11.2 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Met_10 PF02475.16 AAL62798.1 - 3.7e-10 39.9 0.6 7.2e-10 38.9 0.5 1.4 1 1 0 1 1 1 1 Met-10+ like-protein Methyltransf_21 PF05050.12 AAL62798.1 - 8.2e-09 35.7 0.2 1.3e-08 35.1 0.2 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain RrnaAD PF00398.20 AAL62798.1 - 0.0013 17.8 0.0 0.0019 17.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltr_RsmB-F PF01189.17 AAL62798.1 - 0.073 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Glycos_transf_2 PF00535.26 AAL62800.1 - 4.5e-23 81.9 0.0 7.8e-23 81.1 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 AAL62800.1 - 2.5e-07 30.4 0.2 0.0074 15.8 0.1 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 AAL62800.1 - 6.1e-06 26.3 0.0 3e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 DUF1656 PF07869.12 AAL62805.1 - 0.035 14.1 3.0 0.06 13.4 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) Bact_lectin PF18483.1 AAL62807.1 - 5.5e-07 29.8 0.0 9.4e-07 29.0 0.0 1.4 1 1 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 AAL62807.1 - 0.0006 19.4 0.0 0.0032 17.0 0.0 2.0 1 1 0 1 1 1 1 Legume lectin domain Glycos_transf_1 PF00534.20 AAL62809.1 - 1.6e-12 47.3 0.0 2e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAL62809.1 - 2.9e-10 40.7 0.0 3.4e-10 40.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferases group 1 Peptidase_M11 PF05548.11 AAL62818.1 - 1.9e-05 24.0 0.5 4e-05 22.9 0.5 1.5 1 0 0 1 1 1 1 Gametolysin peptidase M11 Reprolysin_5 PF13688.6 AAL62818.1 - 0.025 14.7 0.0 0.05 13.8 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 AAL62818.1 - 0.03 14.2 0.1 0.053 13.4 0.1 1.3 1 0 0 1 1 1 0 Matrixin Peptidase_M66 PF10462.9 AAL62818.1 - 0.039 12.9 0.1 0.062 12.2 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_3 PF13582.6 AAL62818.1 - 0.049 14.1 0.0 0.096 13.2 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 AAL62818.1 - 0.25 10.5 0.2 0.4 9.8 0.2 1.2 1 0 0 1 1 1 0 Met-zincin DUF948 PF06103.11 AAL62820.1 - 1.4e-07 31.7 3.5 0.00048 20.3 0.3 2.5 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF948) DUF3450 PF11932.8 AAL62820.1 - 3.1e-05 23.4 2.1 4e-05 23.0 2.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) TPR_MLP1_2 PF07926.12 AAL62820.1 - 8.7e-05 22.6 4.4 0.00018 21.6 4.3 1.6 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein AAA_13 PF13166.6 AAL62820.1 - 8.7e-05 21.4 2.5 9.9e-05 21.2 2.5 1.1 1 0 0 1 1 1 1 AAA domain MCPsignal PF00015.21 AAL62820.1 - 0.0001 22.1 2.0 0.00015 21.6 2.0 1.3 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain KxDL PF10241.9 AAL62820.1 - 0.00011 22.4 4.3 0.24 11.7 0.2 2.4 1 1 1 2 2 2 2 Uncharacterized conserved protein DUF16 PF01519.16 AAL62820.1 - 0.00012 22.5 3.3 0.00016 22.1 3.3 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF16 DUF1351 PF07083.11 AAL62820.1 - 0.00016 21.5 2.4 0.00025 20.9 2.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1351) EzrA PF06160.12 AAL62820.1 - 0.00017 19.9 6.4 0.00021 19.6 6.4 1.0 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Laminin_II PF06009.12 AAL62820.1 - 0.00021 21.3 5.2 0.0039 17.2 2.6 2.2 1 1 1 2 2 2 1 Laminin Domain II HSBP1 PF06825.12 AAL62820.1 - 0.00026 20.8 14.3 0.25 11.2 0.7 4.6 1 1 2 3 3 3 2 Heat shock factor binding protein 1 Spc7 PF08317.11 AAL62820.1 - 0.00032 19.7 6.4 0.00053 19.0 6.5 1.3 1 1 0 1 1 1 1 Spc7 kinetochore protein DUF1664 PF07889.12 AAL62820.1 - 0.00033 20.7 6.1 0.025 14.6 3.2 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) TMPIT PF07851.13 AAL62820.1 - 0.00044 19.6 0.9 0.00055 19.3 0.9 1.1 1 0 0 1 1 1 1 TMPIT-like protein RmuC PF02646.16 AAL62820.1 - 0.00058 19.1 2.4 0.0009 18.5 2.1 1.5 1 1 0 1 1 1 1 RmuC family ApoLp-III PF07464.11 AAL62820.1 - 0.00062 19.9 2.2 0.003 17.6 2.2 1.7 1 1 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) NPV_P10 PF05531.12 AAL62820.1 - 0.00064 20.1 6.2 0.14 12.7 3.0 2.5 1 1 1 2 2 2 2 Nucleopolyhedrovirus P10 protein Filament PF00038.21 AAL62820.1 - 0.00066 19.4 6.8 0.00081 19.1 6.8 1.1 1 0 0 1 1 1 1 Intermediate filament protein Golgin_A5 PF09787.9 AAL62820.1 - 0.00075 19.1 4.3 0.00093 18.8 4.3 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 Exonuc_VII_L PF02601.15 AAL62820.1 - 0.00079 19.1 1.9 0.00083 19.0 1.9 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit Atg14 PF10186.9 AAL62820.1 - 0.00081 18.6 4.8 0.00084 18.5 4.8 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Snapin_Pallidin PF14712.6 AAL62820.1 - 0.00083 19.7 6.8 0.0079 16.6 0.4 2.3 1 1 1 2 2 2 1 Snapin/Pallidin IFT57 PF10498.9 AAL62820.1 - 0.0011 18.1 1.2 0.0012 17.9 1.2 1.2 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Nup88 PF10168.9 AAL62820.1 - 0.0012 16.8 2.4 0.0013 16.6 2.4 1.0 1 0 0 1 1 1 1 Nuclear pore component Tho2 PF11262.8 AAL62820.1 - 0.0014 17.9 2.0 0.0017 17.6 2.0 1.1 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 DUF4407 PF14362.6 AAL62820.1 - 0.0019 17.6 3.0 0.0021 17.5 3.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Swi5 PF07061.11 AAL62820.1 - 0.0025 17.9 1.7 0.72 10.0 0.7 2.4 2 0 0 2 2 2 1 Swi5 Apolipoprotein PF01442.18 AAL62820.1 - 0.0026 17.6 5.5 0.0044 16.9 4.1 1.9 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Muted PF14942.6 AAL62820.1 - 0.0029 18.0 3.2 0.0039 17.5 3.2 1.3 1 0 0 1 1 1 1 Organelle biogenesis, Muted-like protein CdvA PF18822.1 AAL62820.1 - 0.0032 17.3 1.8 0.0032 17.3 1.8 2.3 1 1 1 2 2 2 1 CdvA-like coiled-coil domain HMMR_N PF15905.5 AAL62820.1 - 0.0034 16.9 4.3 0.0036 16.8 4.3 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal ABC_tran_CTD PF16326.5 AAL62820.1 - 0.0038 17.4 4.6 0.036 14.3 3.9 2.6 1 1 0 1 1 1 1 ABC transporter C-terminal domain Mt_ATP-synt_D PF05873.12 AAL62820.1 - 0.0039 17.1 2.1 0.96 9.3 0.1 2.2 1 1 1 2 2 2 1 ATP synthase D chain, mitochondrial (ATP5H) YjcZ PF13990.6 AAL62820.1 - 0.0047 16.3 0.1 0.0055 16.1 0.1 1.1 1 0 0 1 1 1 1 YjcZ-like protein KH_5 PF13184.6 AAL62820.1 - 0.0048 16.9 4.3 0.058 13.5 3.4 2.7 1 1 0 1 1 1 1 NusA-like KH domain DHR10 PF18595.1 AAL62820.1 - 0.0052 16.8 6.7 0.0073 16.4 5.5 1.8 1 1 1 2 2 1 1 Designed helical repeat protein 10 domain TSKS PF15358.6 AAL62820.1 - 0.0053 15.2 1.3 0.0062 15.0 1.3 1.0 1 0 0 1 1 1 1 Testis-specific serine kinase substrate Fib_alpha PF08702.10 AAL62820.1 - 0.0054 16.9 5.1 0.0082 16.3 5.1 1.3 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family CHD5 PF04420.14 AAL62820.1 - 0.0056 16.6 3.2 0.89 9.4 0.5 2.3 1 1 1 2 2 2 1 CHD5-like protein Nup54 PF13874.6 AAL62820.1 - 0.0058 16.7 3.3 0.01 16.0 3.3 1.4 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 APG17 PF04108.12 AAL62820.1 - 0.0067 15.6 3.9 0.019 14.1 3.3 1.7 1 1 0 1 1 1 1 Autophagy protein Apg17 Prominin PF05478.11 AAL62820.1 - 0.0071 14.4 1.6 0.0075 14.3 1.6 1.1 1 0 0 1 1 1 1 Prominin TMF_DNA_bd PF12329.8 AAL62820.1 - 0.0071 16.3 8.5 0.22 11.6 4.6 2.9 1 1 1 2 2 2 1 TATA element modulatory factor 1 DNA binding DUF4200 PF13863.6 AAL62820.1 - 0.0078 16.6 7.4 0.01 16.2 7.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) TssO PF17561.2 AAL62820.1 - 0.0088 16.2 4.4 0.017 15.2 4.4 1.4 1 1 0 1 1 1 1 Type VI secretion system, TssO COG2 PF06148.11 AAL62820.1 - 0.0091 16.1 3.8 0.031 14.3 2.8 2.2 1 1 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Cep57_MT_bd PF06657.13 AAL62820.1 - 0.0096 16.4 2.7 0.11 12.9 1.4 2.3 1 1 1 2 2 2 1 Centrosome microtubule-binding domain of Cep57 HIP1_clath_bdg PF16515.5 AAL62820.1 - 0.0098 16.5 5.2 0.017 15.7 4.6 1.7 1 1 1 2 2 2 1 Clathrin-binding domain of Huntingtin-interacting protein 1 Transcrip_act PF04949.13 AAL62820.1 - 0.01 15.7 8.7 0.019 14.8 8.7 1.6 1 1 0 1 1 1 0 Transcriptional activator XhlA PF10779.9 AAL62820.1 - 0.011 15.9 14.0 0.047 13.9 9.3 2.3 1 1 1 2 2 2 0 Haemolysin XhlA HAP1_N PF04849.13 AAL62820.1 - 0.011 15.0 4.3 0.016 14.4 4.3 1.4 1 1 0 1 1 1 0 HAP1 N-terminal conserved region Baculo_PEP_C PF04513.12 AAL62820.1 - 0.012 15.7 5.5 0.026 14.6 5.4 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5098 PF17023.5 AAL62820.1 - 0.012 14.6 1.2 0.012 14.6 1.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF5098) HR1 PF02185.16 AAL62820.1 - 0.013 15.6 6.2 1.5 9.0 5.7 2.7 1 1 1 2 2 2 0 Hr1 repeat MscS_porin PF12795.7 AAL62820.1 - 0.013 15.0 7.1 0.085 12.4 6.7 2.1 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain V_ATPase_I PF01496.19 AAL62820.1 - 0.013 13.4 0.6 0.015 13.3 0.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ZapA PF05164.13 AAL62820.1 - 0.014 15.8 4.6 0.61 10.6 4.1 2.7 1 1 1 2 2 1 0 Cell division protein ZapA FliD_C PF07195.12 AAL62820.1 - 0.015 14.7 5.9 0.39 10.1 5.9 2.1 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DUF3552 PF12072.8 AAL62820.1 - 0.016 14.6 7.7 0.017 14.5 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Trimer_CC PF08954.11 AAL62820.1 - 0.016 14.8 7.5 0.37 10.4 2.0 3.1 1 1 2 3 3 3 0 Trimerisation motif FemAB PF02388.16 AAL62820.1 - 0.016 14.1 2.0 0.021 13.7 2.0 1.1 1 0 0 1 1 1 0 FemAB family DUF1732 PF08340.11 AAL62820.1 - 0.02 14.9 5.2 0.72 9.9 5.2 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1732) Laminin_I PF06008.14 AAL62820.1 - 0.022 14.5 5.4 0.032 13.9 5.4 1.3 1 0 0 1 1 1 0 Laminin Domain I DUF4509 PF14970.6 AAL62820.1 - 0.023 14.7 0.5 0.03 14.3 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) LMBR1 PF04791.16 AAL62820.1 - 0.027 13.4 2.6 0.028 13.3 2.6 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein ECH_2 PF16113.5 AAL62820.1 - 0.027 14.0 0.4 0.034 13.6 0.4 1.1 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase LXG PF04740.12 AAL62820.1 - 0.028 14.1 2.2 0.035 13.8 2.2 1.3 1 0 0 1 1 1 0 LXG domain of WXG superfamily DUF2730 PF10805.8 AAL62820.1 - 0.029 14.5 3.0 0.25 11.4 0.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Seryl_tRNA_N PF02403.22 AAL62820.1 - 0.032 14.4 7.6 0.035 14.3 6.9 1.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF148 PF02520.17 AAL62820.1 - 0.033 14.3 3.4 0.057 13.5 3.4 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF148 DUF3498 PF12004.8 AAL62820.1 - 0.039 13.2 2.3 0.045 12.9 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) Fusion_gly PF00523.18 AAL62820.1 - 0.039 12.2 1.0 0.056 11.7 0.6 1.5 1 1 0 1 1 1 0 Fusion glycoprotein F0 TMF_TATA_bd PF12325.8 AAL62820.1 - 0.041 14.1 5.6 0.17 12.1 5.6 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding E2R135 PF11570.8 AAL62820.1 - 0.042 14.2 1.6 0.92 9.8 1.4 2.3 1 1 1 2 2 2 0 Coiled-coil receptor-binding R-domain of colicin E2 DLP_helical PF18709.1 AAL62820.1 - 0.044 13.0 7.1 0.065 12.4 7.1 1.4 1 1 0 1 1 1 0 Dynamin-like helical domain UPF0242 PF06785.11 AAL62820.1 - 0.044 13.9 6.8 0.051 13.7 6.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus BLOC1_2 PF10046.9 AAL62820.1 - 0.046 14.0 5.0 1.2 9.5 4.0 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 WXG100 PF06013.12 AAL62820.1 - 0.047 13.9 1.2 3.2 8.1 0.3 3.1 1 1 1 2 2 2 0 Proteins of 100 residues with WXG FAM76 PF16046.5 AAL62820.1 - 0.05 13.0 2.0 0.057 12.8 2.0 1.1 1 0 0 1 1 1 0 FAM76 protein Allexi_40kDa PF05549.11 AAL62820.1 - 0.051 13.1 1.2 0.061 12.8 1.2 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein HSCB_C PF07743.13 AAL62820.1 - 0.052 14.0 6.9 1.8 9.1 6.9 2.7 1 1 0 1 1 1 0 HSCB C-terminal oligomerisation domain DinI PF06183.13 AAL62820.1 - 0.054 13.8 1.0 12 6.4 0.0 3.2 1 1 2 3 3 2 0 DinI-like family Tropomyosin_1 PF12718.7 AAL62820.1 - 0.055 13.6 7.6 0.25 11.5 7.0 2.0 1 1 1 2 2 2 0 Tropomyosin like VASP_tetra PF08776.11 AAL62820.1 - 0.056 13.0 4.1 23 4.7 0.1 3.7 3 0 0 3 3 3 0 VASP tetramerisation domain DASH_Duo1 PF08651.10 AAL62820.1 - 0.056 13.2 6.9 0.31 10.8 1.8 2.4 1 1 1 2 2 2 0 DASH complex subunit Duo1 Uds1 PF15456.6 AAL62820.1 - 0.058 13.6 4.7 0.19 11.9 4.5 2.0 1 1 0 1 1 1 0 Up-regulated During Septation TBCA PF02970.16 AAL62820.1 - 0.061 13.7 3.8 0.17 12.2 3.8 1.8 1 1 0 1 1 1 0 Tubulin binding cofactor A DUF2802 PF10975.8 AAL62820.1 - 0.062 13.4 2.4 5.4 7.2 2.4 3.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2802) HAUS6_N PF14661.6 AAL62820.1 - 0.063 12.9 1.2 0.078 12.6 1.2 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus MutS_IV PF05190.18 AAL62820.1 - 0.069 13.5 5.2 2.6 8.5 1.2 2.9 1 1 1 2 2 2 0 MutS family domain IV CENP-H PF05837.12 AAL62820.1 - 0.072 13.5 6.4 0.12 12.8 6.1 1.5 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Phage_GPO PF05929.11 AAL62820.1 - 0.076 12.6 0.8 0.093 12.3 0.8 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF2203 PF09969.9 AAL62820.1 - 0.077 13.7 4.0 0.18 12.5 3.8 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Spectrin PF00435.21 AAL62820.1 - 0.077 13.5 2.3 0.19 12.2 2.3 1.7 1 1 0 1 1 1 0 Spectrin repeat HrpB7 PF09486.10 AAL62820.1 - 0.078 13.4 8.9 0.47 10.8 8.6 2.0 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Occludin_ELL PF07303.13 AAL62820.1 - 0.088 13.5 1.5 0.22 12.3 1.5 1.8 1 1 0 1 1 1 0 Occludin homology domain KfrA_N PF11740.8 AAL62820.1 - 0.091 13.4 2.4 0.31 11.7 2.4 1.9 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term Fzo_mitofusin PF04799.13 AAL62820.1 - 0.093 12.3 4.0 0.3 10.6 0.2 2.1 1 1 1 2 2 2 0 fzo-like conserved region FlaC_arch PF05377.11 AAL62820.1 - 0.094 13.1 8.8 0.86 10.0 0.4 3.1 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) DUF885 PF05960.11 AAL62820.1 - 0.11 12.1 0.4 0.13 11.9 0.4 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) USP8_interact PF08941.10 AAL62820.1 - 0.11 12.3 1.8 0.16 11.8 1.8 1.2 1 0 0 1 1 1 0 USP8 interacting DUF1640 PF07798.11 AAL62820.1 - 0.11 12.5 11.2 0.43 10.6 11.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Acyl-CoA_dh_2 PF08028.11 AAL62820.1 - 0.12 12.7 0.1 0.18 12.1 0.1 1.4 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain LUC7 PF03194.15 AAL62820.1 - 0.12 12.1 7.3 0.2 11.3 1.1 1.9 1 1 1 2 2 2 0 LUC7 N_terminus Rad50_zn_hook PF04423.14 AAL62820.1 - 0.13 12.1 3.0 20 5.1 0.4 3.9 1 1 3 4 4 4 0 Rad50 zinc hook motif Phage_Mu_Gam PF07352.12 AAL62820.1 - 0.13 12.2 6.5 1.7 8.6 6.5 2.2 1 1 0 1 1 1 0 Bacteriophage Mu Gam like protein S6OS1 PF15676.5 AAL62820.1 - 0.14 10.6 3.6 0.15 10.5 3.6 1.1 1 0 0 1 1 1 0 Six6 opposite strand transcript 1 family Tweety PF04906.13 AAL62820.1 - 0.15 10.7 0.1 0.18 10.4 0.1 1.1 1 0 0 1 1 1 0 Tweety PRKG1_interact PF15898.5 AAL62820.1 - 0.15 13.0 5.6 0.92 10.4 5.6 2.1 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain SlyX PF04102.12 AAL62820.1 - 0.18 12.5 6.0 2.7 8.7 0.9 2.5 1 1 1 2 2 2 0 SlyX DUF4140 PF13600.6 AAL62820.1 - 0.18 12.3 6.2 0.83 10.1 2.4 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) HalX PF08663.10 AAL62820.1 - 0.19 12.1 10.4 1.1 9.6 1.9 3.2 2 1 1 3 3 2 0 HalX domain SOAR PF16533.5 AAL62820.1 - 0.2 11.6 4.8 11 6.1 4.9 2.8 1 1 1 2 2 2 0 STIM1 Orai1-activating region Prefoldin PF02996.17 AAL62820.1 - 0.21 11.5 5.6 0.95 9.4 0.9 2.4 1 1 1 2 2 2 0 Prefoldin subunit CorA PF01544.18 AAL62820.1 - 0.24 10.7 10.2 0.71 9.1 10.2 1.7 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Hemagglutinin PF00509.18 AAL62820.1 - 0.26 9.6 6.0 0.33 9.3 1.3 2.0 1 1 1 2 2 2 0 Haemagglutinin DUF4665 PF15679.5 AAL62820.1 - 0.28 11.8 4.4 1.8 9.2 1.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4665) DUF1515 PF07439.11 AAL62820.1 - 0.29 11.2 7.5 3.5 7.7 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) RPW8 PF05659.11 AAL62820.1 - 0.31 10.7 5.1 2 8.1 5.1 2.2 1 1 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF4795 PF16043.5 AAL62820.1 - 0.34 10.5 5.7 1.4 8.5 5.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DSX_dimer PF08828.10 AAL62820.1 - 0.36 10.5 4.3 9.9 5.9 0.4 3.2 1 1 2 3 3 3 0 Doublesex dimerisation domain MIP-T3_C PF17749.1 AAL62820.1 - 0.36 10.8 11.4 0.26 11.2 5.0 2.2 1 1 1 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region Cortex-I_coil PF09304.10 AAL62820.1 - 0.37 11.0 9.4 0.35 11.1 2.8 2.4 1 1 1 2 2 2 0 Cortexillin I, coiled coil HU-CCDC81_bac_2 PF18175.1 AAL62820.1 - 0.39 10.6 5.4 23 4.9 0.1 3.3 1 1 3 4 4 4 0 CCDC81-like prokaryotic HU domain 2 MtrG PF04210.13 AAL62820.1 - 0.41 10.5 5.9 5.8 6.8 2.2 3.0 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF3782 PF12644.7 AAL62820.1 - 0.41 10.8 7.1 15 5.8 5.1 2.8 2 1 0 2 2 1 0 Protein of unknown function (DUF3782) Syntaxin_2 PF14523.6 AAL62820.1 - 0.41 11.0 9.8 10 6.6 9.8 2.4 1 1 0 1 1 1 0 Syntaxin-like protein DivIC PF04977.15 AAL62820.1 - 0.5 10.2 8.4 0.38 10.6 2.4 2.4 1 1 1 2 2 2 0 Septum formation initiator YojJ PF10372.9 AAL62820.1 - 0.69 10.1 3.4 6.3 7.0 1.0 3.1 1 1 1 2 2 2 0 Bacterial membrane-spanning protein N-terminus Med9 PF07544.13 AAL62820.1 - 0.82 9.8 7.4 2.4 8.3 7.4 2.0 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 YabA PF06156.13 AAL62820.1 - 0.91 10.2 4.2 2.9 8.6 3.4 2.1 1 1 0 1 1 1 0 Initiation control protein YabA ARGLU PF15346.6 AAL62820.1 - 0.93 9.4 12.1 1.7 8.5 6.0 2.3 1 1 1 2 2 2 0 Arginine and glutamate-rich 1 CCDC-167 PF15188.6 AAL62820.1 - 1.3 9.4 8.6 11 6.4 8.6 2.4 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 zf-C4H2 PF10146.9 AAL62820.1 - 1.9 8.8 6.6 2.4 8.4 6.6 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein DUF5446 PF17522.2 AAL62820.1 - 2.3 8.5 11.3 2.1 8.6 2.3 3.0 1 1 2 3 3 2 0 Family of unknown function (DUF5446) Csm1_N PF18504.1 AAL62820.1 - 2.5 8.5 7.7 12 6.3 0.8 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain Prefoldin_3 PF13758.6 AAL62820.1 - 2.7 8.1 11.0 65 3.7 0.5 2.5 1 1 1 2 2 2 0 Prefoldin subunit DUF4988 PF16378.5 AAL62820.1 - 3.2 7.4 7.4 3.3 7.3 1.7 2.1 1 1 1 2 2 2 0 Domain of unknown function DASH_Dad4 PF08650.10 AAL62820.1 - 3.3 7.8 7.2 6.7 6.8 1.3 2.5 1 1 1 2 2 2 0 DASH complex subunit Dad4 WASH_WAHD PF11945.8 AAL62820.1 - 7.6 6.0 10.0 5.4 6.4 3.8 2.0 1 1 1 2 2 2 0 WAHD domain of WASH complex PaREP1 PF05942.11 AAL62823.1 - 0.0027 17.6 0.0 0.0027 17.6 0.0 1.3 1 1 0 1 1 1 1 Archaeal PaREP1/PaREP8 family PaREP1 PF05942.11 AAL62825.1 - 1.9e-32 111.6 2.8 1.9e-32 111.6 2.8 1.5 2 0 0 2 2 2 1 Archaeal PaREP1/PaREP8 family DUF948 PF06103.11 AAL62827.1 - 7.7e-09 35.7 4.5 4e-05 23.8 0.3 2.7 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF948) KxDL PF10241.9 AAL62827.1 - 7.9e-06 26.1 9.8 0.00013 22.1 3.5 2.3 1 1 1 2 2 2 2 Uncharacterized conserved protein TPR_MLP1_2 PF07926.12 AAL62827.1 - 2.3e-05 24.5 6.4 3e-05 24.1 5.3 1.7 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 AAL62827.1 - 2.8e-05 24.1 16.6 0.00024 21.1 6.2 1.8 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) Filament PF00038.21 AAL62827.1 - 3e-05 23.8 6.6 3.4e-05 23.6 6.6 1.1 1 0 0 1 1 1 1 Intermediate filament protein ApoLp-III PF07464.11 AAL62827.1 - 4e-05 23.8 2.9 0.00084 19.5 2.8 2.1 1 1 1 2 2 2 1 Apolipophorin-III precursor (apoLp-III) DUF16 PF01519.16 AAL62827.1 - 6.2e-05 23.4 4.0 9.2e-05 22.9 4.0 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF16 MCPsignal PF00015.21 AAL62827.1 - 6.8e-05 22.7 2.6 0.00011 22.1 2.6 1.4 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF3450 PF11932.8 AAL62827.1 - 0.0001 21.7 3.4 0.00014 21.3 3.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Laminin_II PF06009.12 AAL62827.1 - 0.00016 21.7 6.3 0.0034 17.4 2.3 2.4 1 1 1 2 2 2 2 Laminin Domain II Atg14 PF10186.9 AAL62827.1 - 0.00017 20.8 6.1 0.00019 20.6 6.1 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_13 PF13166.6 AAL62827.1 - 0.00018 20.3 4.6 0.00021 20.1 4.6 1.1 1 0 0 1 1 1 1 AAA domain Trimer_CC PF08954.11 AAL62827.1 - 0.00024 20.6 7.8 0.12 11.9 0.1 3.1 1 1 2 3 3 3 2 Trimerisation motif Spc7 PF08317.11 AAL62827.1 - 0.00025 20.0 8.0 0.00038 19.4 7.9 1.4 1 1 0 1 1 1 1 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 AAL62827.1 - 0.00029 20.5 2.6 0.00031 20.4 2.6 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit Snapin_Pallidin PF14712.6 AAL62827.1 - 0.00031 21.1 8.2 0.0091 16.4 0.5 2.3 1 1 1 2 2 2 1 Snapin/Pallidin EzrA PF06160.12 AAL62827.1 - 0.00034 18.9 7.4 0.00044 18.6 7.4 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA RmuC PF02646.16 AAL62827.1 - 0.00055 19.2 3.1 0.0011 18.1 2.3 1.8 1 1 0 1 1 1 1 RmuC family DUF1351 PF07083.11 AAL62827.1 - 0.00055 19.8 7.6 0.0023 17.7 8.0 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF1351) Golgin_A5 PF09787.9 AAL62827.1 - 0.00064 19.3 7.1 0.0007 19.1 7.1 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 5 KH_5 PF13184.6 AAL62827.1 - 0.00084 19.4 5.9 0.065 13.3 1.0 2.8 1 1 1 2 2 2 2 NusA-like KH domain TMPIT PF07851.13 AAL62827.1 - 0.00098 18.5 0.7 0.0012 18.2 0.7 1.1 1 0 0 1 1 1 1 TMPIT-like protein MAD PF05557.13 AAL62827.1 - 0.0012 17.3 5.7 0.0013 17.3 5.7 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein DUF4200 PF13863.6 AAL62827.1 - 0.0012 19.2 7.7 0.0017 18.7 7.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) HSBP1 PF06825.12 AAL62827.1 - 0.0012 18.7 17.5 0.097 12.5 1.8 4.7 1 1 2 3 3 3 1 Heat shock factor binding protein 1 IFT57 PF10498.9 AAL62827.1 - 0.0012 17.9 2.9 0.0016 17.5 2.9 1.3 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Fib_alpha PF08702.10 AAL62827.1 - 0.0014 18.8 6.6 0.0021 18.3 6.6 1.3 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family NYD-SP28 PF14772.6 AAL62827.1 - 0.0015 18.5 7.7 0.003 17.6 7.7 1.4 1 0 0 1 1 1 1 Sperm tail HMMR_N PF15905.5 AAL62827.1 - 0.0016 18.0 5.7 0.0017 17.9 5.7 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal Nup88 PF10168.9 AAL62827.1 - 0.0016 16.3 2.4 0.0018 16.2 2.4 1.0 1 0 0 1 1 1 1 Nuclear pore component NPV_P10 PF05531.12 AAL62827.1 - 0.0019 18.6 8.0 0.13 12.8 5.2 2.6 1 1 1 2 2 2 2 Nucleopolyhedrovirus P10 protein WEMBL PF05701.11 AAL62827.1 - 0.0021 16.9 4.7 0.0029 16.4 4.7 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light CENP-H PF05837.12 AAL62827.1 - 0.0024 18.3 5.2 0.0039 17.6 5.2 1.5 1 0 0 1 1 1 1 Centromere protein H (CENP-H) Prominin PF05478.11 AAL62827.1 - 0.0024 15.9 2.0 0.0028 15.7 2.0 1.0 1 0 0 1 1 1 1 Prominin DUF4407 PF14362.6 AAL62827.1 - 0.0025 17.2 4.0 0.0028 17.1 4.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) ABC_tran_CTD PF16326.5 AAL62827.1 - 0.0025 18.0 6.3 0.12 12.6 5.9 2.7 1 1 0 1 1 1 1 ABC transporter C-terminal domain Nup54 PF13874.6 AAL62827.1 - 0.0026 17.9 3.4 0.0044 17.1 3.4 1.3 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 Mt_ATP-synt_D PF05873.12 AAL62827.1 - 0.0028 17.5 2.8 0.42 10.4 2.8 2.5 1 1 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) TBCA PF02970.16 AAL62827.1 - 0.0031 17.8 4.8 0.051 13.9 4.9 2.2 1 1 0 1 1 1 1 Tubulin binding cofactor A FliD_C PF07195.12 AAL62827.1 - 0.0033 16.9 7.0 0.12 11.7 1.1 2.1 1 1 1 2 2 2 2 Flagellar hook-associated protein 2 C-terminus LMBR1 PF04791.16 AAL62827.1 - 0.0034 16.4 2.7 0.0036 16.3 2.7 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein DHR10 PF18595.1 AAL62827.1 - 0.0047 17.0 8.6 0.0068 16.5 6.6 2.0 1 1 0 2 2 1 1 Designed helical repeat protein 10 domain Seryl_tRNA_N PF02403.22 AAL62827.1 - 0.0052 17.0 8.5 0.0059 16.8 8.0 1.5 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Apolipoprotein PF01442.18 AAL62827.1 - 0.0052 16.7 6.2 0.0054 16.6 4.7 1.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain V_ATPase_I PF01496.19 AAL62827.1 - 0.0054 14.7 0.9 0.0066 14.4 0.9 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family VASP_tetra PF08776.11 AAL62827.1 - 0.0061 16.1 5.8 1.2 8.7 0.2 3.7 3 0 0 3 3 3 0 VASP tetramerisation domain Allexi_40kDa PF05549.11 AAL62827.1 - 0.0068 16.0 1.2 0.0084 15.7 1.2 1.2 1 0 0 1 1 1 1 Allexivirus 40kDa protein Cep57_MT_bd PF06657.13 AAL62827.1 - 0.0069 16.8 3.3 0.11 12.9 0.8 2.3 1 1 1 2 2 2 1 Centrosome microtubule-binding domain of Cep57 Fez1 PF06818.15 AAL62827.1 - 0.0069 16.9 3.7 0.0096 16.4 3.7 1.2 1 0 0 1 1 1 1 Fez1 XhlA PF10779.9 AAL62827.1 - 0.0071 16.5 15.9 0.021 15.0 6.5 2.7 1 1 1 2 2 2 1 Haemolysin XhlA Muted PF14942.6 AAL62827.1 - 0.0074 16.6 7.1 0.012 15.9 7.1 1.5 1 1 0 1 1 1 1 Organelle biogenesis, Muted-like protein COG2 PF06148.11 AAL62827.1 - 0.0075 16.4 5.3 0.042 13.9 1.1 2.4 1 1 1 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3552 PF12072.8 AAL62827.1 - 0.0082 15.6 8.0 0.0098 15.3 8.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) Transcrip_act PF04949.13 AAL62827.1 - 0.0086 16.0 9.8 0.02 14.8 9.6 1.9 1 1 0 1 1 1 1 Transcriptional activator Baculo_PEP_C PF04513.12 AAL62827.1 - 0.0086 16.1 6.2 0.019 15.0 5.9 1.8 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus YjcZ PF13990.6 AAL62827.1 - 0.0092 15.4 0.1 0.011 15.2 0.1 1.1 1 0 0 1 1 1 1 YjcZ-like protein FemAB PF02388.16 AAL62827.1 - 0.01 14.8 2.8 0.013 14.4 2.8 1.2 1 0 0 1 1 1 1 FemAB family DUF1732 PF08340.11 AAL62827.1 - 0.011 15.7 5.9 0.37 10.8 3.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1732) TMF_TATA_bd PF12325.8 AAL62827.1 - 0.011 16.0 5.8 0.14 12.4 5.8 2.1 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF5098 PF17023.5 AAL62827.1 - 0.011 14.7 6.8 0.012 14.6 1.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5098) APG17 PF04108.12 AAL62827.1 - 0.012 14.8 4.9 0.027 13.6 4.8 1.6 1 1 0 1 1 1 0 Autophagy protein Apg17 Uds1 PF15456.6 AAL62827.1 - 0.014 15.5 6.1 0.04 14.1 6.1 2.0 1 1 0 1 1 1 0 Up-regulated During Septation Tropomyosin_1 PF12718.7 AAL62827.1 - 0.015 15.4 8.8 0.26 11.5 7.7 2.2 1 1 1 2 2 2 0 Tropomyosin like CR6_interact PF10147.9 AAL62827.1 - 0.016 15.0 2.3 0.017 14.8 2.3 1.1 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 CdvA PF18822.1 AAL62827.1 - 0.016 15.0 9.3 0.22 11.3 0.9 2.5 1 1 1 2 2 2 0 CdvA-like coiled-coil domain ECH_2 PF16113.5 AAL62827.1 - 0.016 14.7 0.6 0.02 14.4 0.6 1.1 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase MscS_porin PF12795.7 AAL62827.1 - 0.016 14.7 9.4 0.094 12.2 8.2 2.2 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain Tropomyosin PF00261.20 AAL62827.1 - 0.017 14.5 8.9 0.045 13.1 8.9 1.7 1 1 0 1 1 1 0 Tropomyosin ATG16 PF08614.11 AAL62827.1 - 0.017 15.3 5.2 0.025 14.8 5.2 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) V-SNARE_C PF12352.8 AAL62827.1 - 0.017 15.4 7.0 0.59 10.5 0.9 3.2 1 1 2 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus DUF2730 PF10805.8 AAL62827.1 - 0.017 15.2 4.2 0.23 11.6 2.9 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) Tho2 PF11262.8 AAL62827.1 - 0.018 14.3 2.3 0.023 13.9 2.3 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 TMF_DNA_bd PF12329.8 AAL62827.1 - 0.018 15.0 11.1 0.54 10.3 6.3 3.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Sec5 PF15469.6 AAL62827.1 - 0.02 14.7 3.5 0.23 11.3 2.8 2.1 1 1 1 2 2 2 0 Exocyst complex component Sec5 TssO PF17561.2 AAL62827.1 - 0.02 15.0 5.3 0.13 12.4 4.7 2.0 1 1 0 1 1 1 0 Type VI secretion system, TssO E2R135 PF11570.8 AAL62827.1 - 0.02 15.2 3.1 1.1 9.6 1.4 2.3 1 1 1 2 2 2 0 Coiled-coil receptor-binding R-domain of colicin E2 ZapA PF05164.13 AAL62827.1 - 0.02 15.3 6.8 1.9 9.0 5.7 3.0 1 1 1 2 2 2 0 Cell division protein ZapA TSKS PF15358.6 AAL62827.1 - 0.021 13.2 1.2 0.024 13.0 1.2 1.1 1 0 0 1 1 1 0 Testis-specific serine kinase substrate KfrA_N PF11740.8 AAL62827.1 - 0.023 15.4 3.2 0.056 14.1 3.2 1.7 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term Occludin_ELL PF07303.13 AAL62827.1 - 0.024 15.4 2.2 0.073 13.8 1.7 1.9 1 1 1 2 2 2 0 Occludin homology domain MutS_IV PF05190.18 AAL62827.1 - 0.025 14.9 6.8 2.6 8.5 0.5 3.2 1 1 2 3 3 3 0 MutS family domain IV WXG100 PF06013.12 AAL62827.1 - 0.026 14.8 2.8 4.8 7.5 1.3 3.6 1 1 1 2 2 2 0 Proteins of 100 residues with WXG DUF2802 PF10975.8 AAL62827.1 - 0.027 14.6 4.2 2.7 8.2 0.4 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2802) BAR_3 PF16746.5 AAL62827.1 - 0.028 14.1 3.5 0.63 9.7 3.4 2.5 1 1 0 1 1 1 0 BAR domain of APPL family Swi5 PF07061.11 AAL62827.1 - 0.028 14.5 4.5 5.9 7.1 4.5 2.6 1 1 0 1 1 1 0 Swi5 DUF4795 PF16043.5 AAL62827.1 - 0.029 14.0 7.8 0.73 9.4 7.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DinI PF06183.13 AAL62827.1 - 0.03 14.6 0.7 8.7 6.8 0.0 3.2 2 1 1 3 3 2 0 DinI-like family HAUS6_N PF14661.6 AAL62827.1 - 0.032 13.8 1.8 0.04 13.5 1.8 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Spectrin PF00435.21 AAL62827.1 - 0.033 14.7 3.2 0.072 13.6 3.3 1.7 1 1 0 1 1 1 0 Spectrin repeat Phage_GPO PF05929.11 AAL62827.1 - 0.034 13.8 0.9 0.039 13.6 0.9 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase HSCB_C PF07743.13 AAL62827.1 - 0.034 14.6 9.1 11 6.6 9.1 2.8 1 1 0 1 1 1 0 HSCB C-terminal oligomerisation domain DUF2203 PF09969.9 AAL62827.1 - 0.035 14.8 5.6 0.26 12.0 5.6 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) HalX PF08663.10 AAL62827.1 - 0.036 14.4 12.2 0.64 10.4 4.0 3.6 2 1 1 3 3 2 0 HalX domain COG6 PF06419.11 AAL62827.1 - 0.036 12.3 5.3 0.12 10.6 1.7 1.9 1 1 1 2 2 2 0 Conserved oligomeric complex COG6 ISG65-75 PF11727.8 AAL62827.1 - 0.048 12.9 1.0 0.066 12.4 1.0 1.3 1 0 0 1 1 1 0 Invariant surface glycoprotein LacI PF00356.21 AAL62827.1 - 0.052 13.3 1.3 12 5.8 0.0 3.5 1 1 2 3 3 3 0 Bacterial regulatory proteins, lacI family Fusion_gly PF00523.18 AAL62827.1 - 0.055 11.7 2.0 0.069 11.4 0.6 1.7 1 1 0 1 1 1 0 Fusion glycoprotein F0 Mod_r PF07200.13 AAL62827.1 - 0.056 13.6 2.7 0.087 12.9 2.7 1.4 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Ran-binding PF05508.11 AAL62827.1 - 0.058 12.4 4.5 0.067 12.2 4.5 1.2 1 0 0 1 1 1 0 RanGTP-binding protein DUF885 PF05960.11 AAL62827.1 - 0.06 13.0 0.5 0.07 12.8 0.5 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) MIP-T3_C PF17749.1 AAL62827.1 - 0.063 13.2 13.4 0.27 11.2 4.9 2.4 1 1 2 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region DASH_Duo1 PF08651.10 AAL62827.1 - 0.064 13.0 7.7 0.32 10.8 1.8 2.6 1 1 1 2 2 2 0 DASH complex subunit Duo1 UPF0242 PF06785.11 AAL62827.1 - 0.065 13.3 6.1 0.075 13.1 6.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SlyX PF04102.12 AAL62827.1 - 0.07 13.8 8.0 2.5 8.8 1.6 2.5 1 1 1 2 2 2 0 SlyX DLP_helical PF18709.1 AAL62827.1 - 0.075 12.2 8.5 0.41 9.8 8.7 1.8 1 1 1 2 2 2 0 Dynamin-like helical domain FlaC_arch PF05377.11 AAL62827.1 - 0.081 13.3 10.4 0.9 10.0 0.3 3.2 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DSX_dimer PF08828.10 AAL62827.1 - 0.085 12.5 6.8 41 3.9 4.3 3.5 1 1 1 2 2 2 0 Doublesex dimerisation domain Rad50_zn_hook PF04423.14 AAL62827.1 - 0.088 12.7 4.3 37 4.3 0.1 4.3 1 1 5 6 6 6 0 Rad50 zinc hook motif HrpB7 PF09486.10 AAL62827.1 - 0.094 13.1 11.9 0.15 12.4 6.0 2.2 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) LUC7 PF03194.15 AAL62827.1 - 0.096 12.3 8.5 0.46 10.1 8.7 1.8 1 1 1 2 2 2 0 LUC7 N_terminus Acyl-CoA_dh_2 PF08028.11 AAL62827.1 - 0.097 12.9 0.2 0.21 11.8 0.2 1.6 1 1 1 2 2 1 0 Acyl-CoA dehydrogenase, C-terminal domain Med22 PF06179.12 AAL62827.1 - 0.1 12.8 6.4 0.92 9.7 2.3 2.6 1 1 1 2 2 2 0 Surfeit locus protein 5 subunit 22 of Mediator complex DUF724 PF05266.14 AAL62827.1 - 0.1 12.4 1.6 0.15 11.9 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) FAM76 PF16046.5 AAL62827.1 - 0.1 11.9 3.6 0.12 11.7 3.6 1.1 1 0 0 1 1 1 0 FAM76 protein Herpes_UL14 PF03580.14 AAL62827.1 - 0.1 12.8 6.6 0.17 12.1 6.6 1.4 1 1 0 1 1 1 0 Herpesvirus UL14-like protein DUF4140 PF13600.6 AAL62827.1 - 0.11 13.0 8.6 37 4.8 8.6 2.4 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF3498 PF12004.8 AAL62827.1 - 0.11 11.7 3.3 0.12 11.6 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) DUF3782 PF12644.7 AAL62827.1 - 0.11 12.6 8.9 1.7 8.9 0.8 2.8 2 1 1 3 3 2 0 Protein of unknown function (DUF3782) CREPT PF16566.5 AAL62827.1 - 0.12 12.5 3.9 0.25 11.5 3.7 1.7 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour CHD5 PF04420.14 AAL62827.1 - 0.12 12.2 4.5 9.7 6.0 4.5 2.4 1 1 0 1 1 1 0 CHD5-like protein FUSC PF04632.12 AAL62827.1 - 0.13 10.7 0.4 0.13 10.8 0.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family BLOC1_2 PF10046.9 AAL62827.1 - 0.15 12.4 6.0 0.91 9.9 5.0 2.2 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LXG PF04740.12 AAL62827.1 - 0.16 11.7 5.3 0.27 10.9 5.2 1.5 1 1 0 1 1 1 0 LXG domain of WXG superfamily Phage_Mu_Gam PF07352.12 AAL62827.1 - 0.16 11.9 8.9 0.18 11.7 3.3 2.3 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein Ku_C PF03730.14 AAL62827.1 - 0.16 12.7 3.0 1.9 9.2 0.2 2.5 1 1 1 2 2 2 0 Ku70/Ku80 C-terminal arm Cortex-I_coil PF09304.10 AAL62827.1 - 0.18 12.0 10.8 0.39 10.9 2.8 2.6 1 1 1 2 2 2 0 Cortexillin I, coiled coil Fzo_mitofusin PF04799.13 AAL62827.1 - 0.19 11.3 5.0 0.34 10.5 0.5 2.1 1 1 1 2 2 2 0 fzo-like conserved region YkyA PF10368.9 AAL62827.1 - 0.2 11.3 7.4 0.43 10.2 2.1 2.1 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein Prefoldin PF02996.17 AAL62827.1 - 0.2 11.6 7.1 1.1 9.2 0.8 2.4 1 1 1 2 2 2 0 Prefoldin subunit DUF745 PF05335.13 AAL62827.1 - 0.22 11.2 1.3 0.62 9.8 1.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF745) Syntaxin_2 PF14523.6 AAL62827.1 - 0.22 11.9 11.4 14 6.1 11.4 2.6 1 1 0 1 1 1 0 Syntaxin-like protein Vip3A_N PF12495.8 AAL62827.1 - 0.23 11.4 4.3 2 8.3 3.9 2.0 1 1 1 2 2 2 0 Vegetative insecticide protein 3A N terminal ACCA PF03255.14 AAL62827.1 - 0.23 11.3 4.9 1.1 9.1 4.9 2.0 1 1 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit SOAR PF16533.5 AAL62827.1 - 0.25 11.3 7.0 2.1 8.4 1.1 3.0 1 1 3 4 4 4 0 STIM1 Orai1-activating region RPW8 PF05659.11 AAL62827.1 - 0.26 11.0 6.6 0.77 9.4 1.5 2.4 1 1 2 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Phasin PF05597.11 AAL62827.1 - 0.29 11.2 5.7 0.56 10.2 5.0 1.9 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF1640 PF07798.11 AAL62827.1 - 0.29 11.2 13.0 7.1 6.6 7.3 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) Fmp27_WPPW PF10359.9 AAL62827.1 - 0.29 9.9 7.7 0.43 9.4 7.7 1.4 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF148 PF02520.17 AAL62827.1 - 0.31 11.1 7.1 0.87 9.7 7.1 1.9 1 1 0 1 1 1 0 Domain of unknown function DUF148 PRKG1_interact PF15898.5 AAL62827.1 - 0.33 11.9 7.1 1.7 9.6 7.1 2.1 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain DUF4446 PF14584.6 AAL62827.1 - 0.35 10.8 5.4 1.4 8.9 3.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) S6OS1 PF15676.5 AAL62827.1 - 0.35 9.3 5.1 0.36 9.3 5.1 1.1 1 0 0 1 1 1 0 Six6 opposite strand transcript 1 family DUF4988 PF16378.5 AAL62827.1 - 0.37 10.4 8.8 0.22 11.2 1.3 2.1 1 1 1 2 2 2 0 Domain of unknown function Pullulanase_Ins PF18494.1 AAL62827.1 - 0.37 11.3 2.4 2.3 8.8 1.8 2.5 1 1 1 2 2 2 0 Pullulanase Ins domain DUF1515 PF07439.11 AAL62827.1 - 0.38 10.8 9.7 2.8 8.0 1.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) DivIC PF04977.15 AAL62827.1 - 0.39 10.5 11.3 0.38 10.6 2.3 2.6 1 1 1 2 2 2 0 Septum formation initiator MtrG PF04210.13 AAL62827.1 - 0.43 10.5 7.5 3.3 7.6 1.6 3.2 1 1 2 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G CCDC-167 PF15188.6 AAL62827.1 - 0.43 10.9 10.0 42 4.6 9.8 2.7 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 HIP1_clath_bdg PF16515.5 AAL62827.1 - 0.43 11.2 5.6 0.76 10.4 4.7 1.8 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 APG6_N PF17675.1 AAL62827.1 - 0.44 11.1 5.9 0.85 10.1 5.7 1.6 1 1 1 2 2 1 0 Apg6 coiled-coil region Med9 PF07544.13 AAL62827.1 - 0.48 10.6 8.6 1.9 8.6 8.6 2.0 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 YabA PF06156.13 AAL62827.1 - 0.56 10.9 4.8 1.8 9.3 4.1 2.1 1 1 0 1 1 1 0 Initiation control protein YabA CorA PF01544.18 AAL62827.1 - 0.58 9.4 11.0 1.3 8.2 11.0 1.6 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF5446 PF17522.2 AAL62827.1 - 0.67 10.2 13.0 0.66 10.2 3.8 3.0 1 1 2 3 3 2 0 Family of unknown function (DUF5446) HU-CCDC81_bac_2 PF18175.1 AAL62827.1 - 0.67 9.9 6.3 25 4.8 0.1 3.5 1 1 3 4 4 4 0 CCDC81-like prokaryotic HU domain 2 EspB PF05802.11 AAL62827.1 - 0.69 9.9 5.4 2.1 8.3 5.4 1.8 1 1 0 1 1 1 0 Enterobacterial EspB protein DUF4665 PF15679.5 AAL62827.1 - 0.73 10.5 5.2 2.1 9.0 1.2 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4665) Hemagglutinin PF00509.18 AAL62827.1 - 0.84 8.0 7.2 0.79 8.1 1.8 1.9 1 1 1 2 2 2 0 Haemagglutinin DUF1910 PF08928.10 AAL62827.1 - 1 9.4 5.2 29 4.7 5.2 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF1910) YojJ PF10372.9 AAL62827.1 - 1.2 9.3 4.4 10 6.3 0.1 3.2 1 1 2 3 3 3 0 Bacterial membrane-spanning protein N-terminus DUF4404 PF14357.6 AAL62827.1 - 1.2 9.8 5.5 4.6 7.9 0.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) NPA PF16469.5 AAL62827.1 - 1.7 9.2 5.4 5.7 7.5 0.8 2.5 2 1 1 3 3 2 0 Nematode polyprotein allergen ABA-1 TolA_bind_tri PF16331.5 AAL62827.1 - 1.7 8.8 9.7 4.3 7.5 4.2 2.5 1 1 1 2 2 2 0 TolA binding protein trimerisation Csm1_N PF18504.1 AAL62827.1 - 2.1 8.7 9.5 12 6.3 2.9 2.6 1 1 1 2 2 2 0 Csm1 N-terminal domain WASH_WAHD PF11945.8 AAL62827.1 - 2.3 7.7 12.2 6.5 6.2 3.9 2.1 1 1 1 2 2 2 0 WAHD domain of WASH complex DASH_Dad4 PF08650.10 AAL62827.1 - 2.9 7.9 9.2 3.4 7.7 1.5 2.7 1 1 2 3 3 3 0 DASH complex subunit Dad4 DUF4254 PF14063.6 AAL62827.1 - 4.1 7.2 15.6 4.4 7.1 4.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4254) Prefoldin_3 PF13758.6 AAL62827.1 - 4.1 7.5 13.4 5.9 7.0 4.4 3.0 1 1 1 2 2 2 0 Prefoldin subunit Alanine_zipper PF11839.8 AAL62827.1 - 5.3 7.5 5.5 31 5.0 1.6 3.5 2 1 1 3 3 1 0 Alanine-zipper, major outer membrane lipoprotein DASH_Dad1 PF08649.10 AAL62827.1 - 7.6 6.8 10.6 11 6.3 2.2 3.1 1 1 1 2 2 2 0 DASH complex subunit Dad1 MazE_antitoxin PF04014.18 AAL62829.1 - 7e-10 38.6 0.2 9.6e-10 38.2 0.2 1.3 1 0 0 1 1 1 1 Antidote-toxin recognition MazE, bacterial antitoxin Lip_prot_lig_C PF10437.9 AAL62829.1 - 0.004 17.1 0.0 0.0049 16.8 0.0 1.1 1 0 0 1 1 1 1 Bacterial lipoate protein ligase C-terminus PIN PF01850.21 AAL62830.1 - 0.00015 22.2 0.0 0.00017 22.1 0.0 1.1 1 0 0 1 1 1 1 PIN domain zf-FPG_IleRS PF06827.14 AAL62832.1 - 0.13 12.1 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS DUF948 PF06103.11 AAL62833.1 - 1.1e-15 57.7 17.8 0.00028 21.1 3.7 4.8 1 1 2 3 3 3 3 Bacterial protein of unknown function (DUF948) Apolipoprotein PF01442.18 AAL62833.1 - 9.4e-11 41.9 16.5 5.6e-10 39.4 15.7 2.3 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain HSBP1 PF06825.12 AAL62833.1 - 2.2e-09 37.0 38.6 0.13 12.1 2.0 8.6 1 1 8 9 9 9 4 Heat shock factor binding protein 1 DUF1664 PF07889.12 AAL62833.1 - 4.5e-09 36.4 20.9 0.0011 19.0 7.2 3.9 1 1 4 5 5 5 5 Protein of unknown function (DUF1664) Trimer_CC PF08954.11 AAL62833.1 - 7.9e-09 34.9 25.9 0.014 14.9 2.3 7.2 1 1 7 8 8 8 3 Trimerisation motif ApoLp-III PF07464.11 AAL62833.1 - 1.5e-08 34.9 14.1 0.00019 21.5 4.8 3.3 1 1 2 3 3 3 2 Apolipophorin-III precursor (apoLp-III) KxDL PF10241.9 AAL62833.1 - 1.6e-08 34.7 15.8 0.00098 19.3 3.3 4.1 1 1 3 4 4 4 3 Uncharacterized conserved protein DinI PF06183.13 AAL62833.1 - 6.4e-08 32.8 14.9 0.35 11.2 1.6 7.8 2 1 5 7 7 6 1 DinI-like family Exonuc_VII_L PF02601.15 AAL62833.1 - 4.5e-07 29.7 14.4 0.00012 21.7 8.1 2.0 1 1 1 2 2 2 2 Exonuclease VII, large subunit MCPsignal PF00015.21 AAL62833.1 - 6.3e-07 29.4 19.4 0.0002 21.2 10.7 2.7 1 1 2 3 3 3 3 Methyl-accepting chemotaxis protein (MCP) signalling domain Laminin_II PF06009.12 AAL62833.1 - 1.5e-06 28.3 19.2 0.0024 17.9 3.7 3.6 1 1 2 3 3 3 3 Laminin Domain II FliD_C PF07195.12 AAL62833.1 - 1.6e-06 27.8 18.1 0.0045 16.4 3.6 3.5 1 1 2 3 3 3 2 Flagellar hook-associated protein 2 C-terminus NPV_P10 PF05531.12 AAL62833.1 - 2e-06 28.1 22.2 0.16 12.5 3.6 4.8 1 1 2 3 3 3 2 Nucleopolyhedrovirus P10 protein MscS_porin PF12795.7 AAL62833.1 - 2.3e-06 27.4 19.1 9.8e-05 22.0 11.7 2.4 1 1 1 2 2 2 2 Mechanosensitive ion channel porin domain TPR_MLP1_2 PF07926.12 AAL62833.1 - 2.3e-06 27.7 17.1 0.00011 22.3 3.4 3.7 1 1 2 3 3 3 1 TPR/MLP1/MLP2-like protein CdvA PF18822.1 AAL62833.1 - 2.3e-06 27.4 26.3 0.09 12.6 4.5 4.2 1 1 3 4 4 4 3 CdvA-like coiled-coil domain Baculo_PEP_C PF04513.12 AAL62833.1 - 2.7e-06 27.5 18.6 0.013 15.6 4.2 3.3 1 1 2 3 3 3 3 Baculovirus polyhedron envelope protein, PEP, C terminus DUF16 PF01519.16 AAL62833.1 - 3.6e-06 27.4 26.8 0.0042 17.5 8.9 3.0 1 1 1 2 2 2 2 Protein of unknown function DUF16 AAA_13 PF13166.6 AAL62833.1 - 4e-06 25.8 22.7 1.5e-05 23.9 22.4 1.9 1 1 0 1 1 1 1 AAA domain KH_5 PF13184.6 AAL62833.1 - 4.4e-06 26.7 23.8 0.013 15.5 1.3 5.8 1 1 4 5 5 5 1 NusA-like KH domain RmuC PF02646.16 AAL62833.1 - 4.5e-06 26.0 14.2 0.0031 16.7 2.1 3.2 1 1 2 3 3 3 2 RmuC family DUF4407 PF14362.6 AAL62833.1 - 5.4e-06 26.0 22.7 0.00028 20.3 12.7 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4407) DUF3584 PF12128.8 AAL62833.1 - 6.7e-06 24.0 17.4 1.1e-05 23.3 17.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) VASP_tetra PF08776.11 AAL62833.1 - 9.9e-06 25.0 22.2 1.9 8.1 0.1 8.1 8 0 0 8 8 7 0 VASP tetramerisation domain ABC_tran_CTD PF16326.5 AAL62833.1 - 1.2e-05 25.5 17.2 0.093 13.0 2.4 4.4 1 1 2 3 3 3 2 ABC transporter C-terminal domain Mt_ATP-synt_D PF05873.12 AAL62833.1 - 1.3e-05 25.1 14.5 0.53 10.1 0.3 4.9 1 1 3 4 4 4 1 ATP synthase D chain, mitochondrial (ATP5H) GAS PF13851.6 AAL62833.1 - 1.7e-05 24.2 18.0 0.00023 20.6 17.6 2.0 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 AAL62833.1 - 2.1e-05 23.6 22.2 0.00039 19.4 6.4 2.2 1 1 1 2 2 2 1 Spc7 kinetochore protein TMPIT PF07851.13 AAL62833.1 - 2.1e-05 24.0 11.8 0.0097 15.2 4.6 2.2 1 1 1 2 2 2 2 TMPIT-like protein Fib_alpha PF08702.10 AAL62833.1 - 2.4e-05 24.6 23.4 0.016 15.4 6.0 2.9 1 1 2 3 3 3 2 Fibrinogen alpha/beta chain family EzrA PF06160.12 AAL62833.1 - 3.6e-05 22.1 22.1 0.00054 18.3 21.7 2.1 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA Muted PF14942.6 AAL62833.1 - 4.1e-05 24.0 18.8 0.028 14.7 10.7 2.4 1 1 1 2 2 2 2 Organelle biogenesis, Muted-like protein Filament PF00038.21 AAL62833.1 - 4.5e-05 23.2 24.2 0.00047 19.8 8.7 2.4 1 1 1 2 2 2 1 Intermediate filament protein DUF1732 PF08340.11 AAL62833.1 - 5.7e-05 23.0 17.0 0.28 11.2 1.6 5.1 1 1 3 4 4 4 1 Domain of unknown function (DUF1732) TMP_2 PF06791.13 AAL62833.1 - 6.4e-05 22.7 0.1 0.13 11.9 0.1 2.8 1 1 1 2 2 2 1 Prophage tail length tape measure protein Spectrin PF00435.21 AAL62833.1 - 9.4e-05 22.9 13.4 0.0069 16.9 6.2 2.4 1 1 1 2 2 2 2 Spectrin repeat TACC_C PF05010.14 AAL62833.1 - 9.7e-05 22.2 16.8 0.00063 19.6 17.1 2.1 1 1 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal HAP1_N PF04849.13 AAL62833.1 - 0.00014 21.2 16.6 0.0068 15.6 3.0 2.8 1 1 1 2 2 2 1 HAP1 N-terminal conserved region HalX PF08663.10 AAL62833.1 - 0.00016 21.9 25.3 0.096 13.0 1.5 6.2 1 1 4 5 5 5 1 HalX domain Transcrip_act PF04949.13 AAL62833.1 - 0.0002 21.3 28.3 0.15 11.9 3.9 3.8 1 1 2 3 3 3 2 Transcriptional activator DUF4455 PF14643.6 AAL62833.1 - 0.00023 20.0 15.0 0.0025 16.6 1.5 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4455) HSCB_C PF07743.13 AAL62833.1 - 0.00029 21.3 23.6 1.8e+04 -6.5 23.6 5.2 1 1 0 1 1 0 0 HSCB C-terminal oligomerisation domain Fzo_mitofusin PF04799.13 AAL62833.1 - 0.0003 20.4 15.5 0.13 11.8 0.4 4.3 1 1 4 5 5 5 1 fzo-like conserved region DUF2703 PF10865.8 AAL62833.1 - 0.00035 20.7 5.9 2.4 8.3 0.7 4.3 1 1 3 4 4 4 0 Domain of unknown function (DUF2703) MIS13 PF08202.11 AAL62833.1 - 0.00039 19.8 12.1 0.011 15.1 2.6 2.2 1 1 1 2 2 2 2 Mis12-Mtw1 protein family TMF_DNA_bd PF12329.8 AAL62833.1 - 0.0004 20.3 23.1 0.85 9.7 3.5 5.2 1 1 2 4 4 4 0 TATA element modulatory factor 1 DNA binding Nup54 PF13874.6 AAL62833.1 - 0.00047 20.3 16.3 0.025 14.7 8.1 2.4 1 1 1 2 2 2 2 Nucleoporin complex subunit 54 Snapin_Pallidin PF14712.6 AAL62833.1 - 0.00051 20.4 23.4 0.015 15.7 0.4 4.4 1 1 3 4 4 4 2 Snapin/Pallidin Uds1 PF15456.6 AAL62833.1 - 0.00051 20.2 17.2 1 9.6 12.4 3.5 1 1 2 3 3 3 0 Up-regulated During Septation Tropomyosin PF00261.20 AAL62833.1 - 0.00053 19.4 24.5 0.0053 16.2 24.6 2.5 1 1 0 1 1 1 1 Tropomyosin IFT57 PF10498.9 AAL62833.1 - 0.00056 19.0 19.5 0.058 12.4 8.9 2.2 1 1 1 2 2 2 2 Intra-flagellar transport protein 57 T3SSipB PF16535.5 AAL62833.1 - 0.00068 20.1 4.6 0.6 10.6 0.1 2.8 1 1 1 2 2 2 1 Type III cell invasion protein SipB DUF4795 PF16043.5 AAL62833.1 - 0.00068 19.3 20.5 0.015 14.9 20.1 2.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4795) Tropomyosin_1 PF12718.7 AAL62833.1 - 0.0007 19.8 23.5 0.031 14.4 3.9 2.9 1 1 1 2 2 2 2 Tropomyosin like BAR_3 PF16746.5 AAL62833.1 - 0.0008 19.2 12.9 0.11 12.2 0.5 3.9 1 1 2 4 4 4 1 BAR domain of APPL family ATF7IP_BD PF16788.5 AAL62833.1 - 0.00088 19.4 13.9 0.083 13.0 1.3 3.5 1 1 3 4 4 3 2 ATF-interacting protein binding domain Mod_r PF07200.13 AAL62833.1 - 0.00089 19.4 9.1 0.49 10.5 9.1 2.8 1 1 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein TBCA PF02970.16 AAL62833.1 - 0.00092 19.5 15.5 0.63 10.4 2.5 4.2 1 1 2 3 3 3 1 Tubulin binding cofactor A APG17 PF04108.12 AAL62833.1 - 0.0011 18.2 16.7 0.1 11.7 3.8 2.4 1 1 0 1 1 1 1 Autophagy protein Apg17 HIP1_clath_bdg PF16515.5 AAL62833.1 - 0.0012 19.4 17.1 0.37 11.4 1.6 4.0 1 1 4 5 5 5 1 Clathrin-binding domain of Huntingtin-interacting protein 1 PMC2NT PF08066.12 AAL62833.1 - 0.0016 19.1 11.7 0.51 11.1 4.3 4.1 1 1 2 3 3 3 1 PMC2NT (NUC016) domain DUF3450 PF11932.8 AAL62833.1 - 0.0016 17.8 19.1 0.1 11.9 7.9 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3450) SHE3 PF17078.5 AAL62833.1 - 0.0018 18.0 19.5 0.43 10.3 19.5 2.9 1 1 0 1 1 1 1 SWI5-dependent HO expression protein 3 XhlA PF10779.9 AAL62833.1 - 0.0019 18.4 40.0 0.034 14.4 9.8 5.1 1 1 5 6 6 6 2 Haemolysin XhlA WXG100 PF06013.12 AAL62833.1 - 0.0019 18.4 10.2 15 5.9 0.9 5.5 1 1 3 4 4 4 0 Proteins of 100 residues with WXG Occludin_ELL PF07303.13 AAL62833.1 - 0.0021 18.8 9.4 0.37 11.5 0.8 3.5 1 1 3 4 4 4 1 Occludin homology domain DUF148 PF02520.17 AAL62833.1 - 0.0021 18.2 18.3 0.23 11.6 7.6 3.3 1 1 3 4 4 4 2 Domain of unknown function DUF148 BLOC1_2 PF10046.9 AAL62833.1 - 0.0021 18.3 17.4 0.25 11.6 2.1 3.7 1 1 2 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 T7SS_ESX_EspC PF10824.8 AAL62833.1 - 0.0021 18.5 0.0 0.99 9.9 0.0 2.9 1 1 1 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm DUF4854 PF16146.5 AAL62833.1 - 0.0023 18.3 1.9 8.8 6.7 0.1 3.7 1 1 3 4 4 4 0 Domain of unknown function (DUF4854) KMP11 PF03037.16 AAL62833.1 - 0.0023 18.7 9.1 2.2 9.1 0.8 5.0 1 1 2 4 4 3 0 Kinetoplastid membrane protein 11 HMMR_N PF15905.5 AAL62833.1 - 0.0025 17.4 20.8 0.059 12.8 12.9 2.1 1 1 1 2 2 2 2 Hyaluronan mediated motility receptor N-terminal YjcZ PF13990.6 AAL62833.1 - 0.0026 17.2 4.1 0.51 9.7 0.9 2.4 1 1 1 2 2 2 1 YjcZ-like protein Golgin_A5 PF09787.9 AAL62833.1 - 0.0033 17.0 17.5 0.0033 17.0 17.5 1.9 1 1 1 2 2 2 1 Golgin subfamily A member 5 Uso1_p115_C PF04871.13 AAL62833.1 - 0.0033 17.8 8.1 0.73 10.2 0.7 2.7 1 1 1 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region HAUS-augmin3 PF14932.6 AAL62833.1 - 0.0035 17.0 6.7 0.56 9.7 0.6 2.6 1 1 2 3 3 3 1 HAUS augmin-like complex subunit 3 HR1 PF02185.16 AAL62833.1 - 0.0036 17.4 21.5 2.1 8.5 0.4 5.3 1 1 3 4 4 4 0 Hr1 repeat LacI PF00356.21 AAL62833.1 - 0.0039 16.9 11.4 17 5.3 0.1 7.2 2 1 6 8 8 6 0 Bacterial regulatory proteins, lacI family DUF3782 PF12644.7 AAL62833.1 - 0.0042 17.2 21.5 4.6 7.5 0.8 5.4 2 1 3 5 5 4 0 Protein of unknown function (DUF3782) DUF2937 PF11157.8 AAL62833.1 - 0.0042 16.8 4.7 0.56 9.9 0.5 2.7 1 1 3 4 4 4 1 Protein of unknown function (DUF2937) Stathmin PF00836.19 AAL62833.1 - 0.0043 17.0 14.6 0.09 12.8 1.7 2.7 1 1 1 2 2 2 1 Stathmin family FUSC PF04632.12 AAL62833.1 - 0.0046 15.6 2.2 0.0071 15.0 1.2 1.6 1 1 1 2 2 2 1 Fusaric acid resistance protein family Tektin PF03148.14 AAL62833.1 - 0.0047 15.7 30.4 0.17 10.6 5.1 3.1 1 1 2 3 3 3 2 Tektin family TMF_TATA_bd PF12325.8 AAL62833.1 - 0.0057 16.9 17.5 0.35 11.1 4.0 3.5 1 1 2 3 3 3 1 TATA element modulatory factor 1 TATA binding Collagen_mid PF15984.5 AAL62833.1 - 0.0058 16.4 0.0 0.11 12.2 0.0 2.0 1 1 1 2 2 2 1 Bacterial collagen, middle region Not3 PF04065.15 AAL62833.1 - 0.0061 16.0 18.2 0.076 12.4 4.6 3.0 1 1 1 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component RasGAP_C PF03836.15 AAL62833.1 - 0.0062 16.7 19.6 0.16 12.1 4.0 3.2 1 1 2 3 3 3 2 RasGAP C-terminus NYD-SP28 PF14772.6 AAL62833.1 - 0.0065 16.5 25.0 0.35 10.9 9.0 3.4 1 1 2 3 3 3 1 Sperm tail Prominin PF05478.11 AAL62833.1 - 0.0067 14.5 16.1 0.019 12.9 16.1 1.8 1 1 0 1 1 1 1 Prominin ISG65-75 PF11727.8 AAL62833.1 - 0.0072 15.6 15.6 0.23 10.7 3.1 2.3 1 1 1 2 2 2 2 Invariant surface glycoprotein Taxilin PF09728.9 AAL62833.1 - 0.0094 15.2 18.6 0.02 14.1 13.9 2.1 1 1 1 2 2 2 1 Myosin-like coiled-coil protein Sulfatase_C PF14707.6 AAL62833.1 - 0.0096 16.7 4.0 30 5.4 0.2 4.0 1 1 4 5 5 5 0 C-terminal region of aryl-sulfatase CCDC154 PF15450.6 AAL62833.1 - 0.0097 14.5 22.0 0.066 11.8 14.1 2.6 1 1 1 2 2 2 2 Coiled-coil domain-containing protein 154 Phage_Mu_Gam PF07352.12 AAL62833.1 - 0.01 15.8 25.4 1.1 9.2 3.9 4.1 1 1 3 4 4 4 0 Bacteriophage Mu Gam like protein Allexi_40kDa PF05549.11 AAL62833.1 - 0.01 15.4 13.0 0.09 12.3 2.4 2.6 1 1 2 3 3 3 0 Allexivirus 40kDa protein DUF1043 PF06295.12 AAL62833.1 - 0.011 15.8 3.1 7.6 6.6 1.8 3.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) Erythro-docking PF09277.11 AAL62833.1 - 0.011 15.6 5.0 7.5 6.5 0.2 5.2 1 1 4 5 5 4 0 Erythronolide synthase, docking T3SS_basalb_I PF17001.5 AAL62833.1 - 0.011 16.3 2.6 24 5.6 1.1 4.0 1 1 1 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI Phage_GPO PF05929.11 AAL62833.1 - 0.011 15.4 10.6 0.065 12.8 1.9 2.2 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase YabA PF06156.13 AAL62833.1 - 0.012 16.2 16.3 0.44 11.2 4.2 3.5 1 1 2 3 3 3 0 Initiation control protein YabA ARGLU PF15346.6 AAL62833.1 - 0.013 15.4 31.5 0.65 9.9 3.5 3.9 1 1 2 3 3 3 0 Arginine and glutamate-rich 1 Swi5 PF07061.11 AAL62833.1 - 0.014 15.5 15.4 7.9 6.6 0.8 4.9 1 1 2 3 3 3 0 Swi5 Atg14 PF10186.9 AAL62833.1 - 0.014 14.5 24.8 0.058 12.5 12.4 2.4 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2333 PF10095.9 AAL62833.1 - 0.016 14.2 4.6 0.48 9.4 1.4 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2333) DLP_helical PF18709.1 AAL62833.1 - 0.018 14.3 23.6 0.017 14.3 14.5 2.2 1 1 1 2 2 2 0 Dynamin-like helical domain Syntaxin_2 PF14523.6 AAL62833.1 - 0.023 15.1 28.7 2.6 8.4 8.0 4.1 1 1 3 4 4 4 0 Syntaxin-like protein DUF745 PF05335.13 AAL62833.1 - 0.024 14.4 6.9 0.19 11.4 2.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF745) Perilipin PF03036.16 AAL62833.1 - 0.025 13.6 4.9 0.1 11.6 4.9 1.8 1 1 0 1 1 1 0 Perilipin family LUC7 PF03194.15 AAL62833.1 - 0.026 14.2 25.6 0.3 10.7 6.4 3.2 1 1 2 3 3 3 0 LUC7 N_terminus Tho2 PF11262.8 AAL62833.1 - 0.028 13.6 17.4 0.08 12.1 6.8 2.1 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Sec16_C PF12931.7 AAL62833.1 - 0.029 14.0 0.4 3.7 7.1 0.1 2.9 1 1 3 4 4 4 0 Sec23-binding domain of Sec16 Mobilization_B PF17511.2 AAL62833.1 - 0.031 14.7 9.7 4.7 7.6 1.4 4.2 1 1 4 5 5 5 0 Mobilization protein B YlqD PF11068.8 AAL62833.1 - 0.033 14.6 18.1 0.3 11.5 4.4 3.1 1 1 2 3 3 3 0 YlqD protein DUF2203 PF09969.9 AAL62833.1 - 0.034 14.9 18.2 0.52 11.1 1.8 3.3 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) AIP3 PF03915.13 AAL62833.1 - 0.035 13.2 22.8 0.11 11.5 22.8 1.8 1 1 0 1 1 1 0 Actin interacting protein 3 DUF2802 PF10975.8 AAL62833.1 - 0.04 14.0 14.5 14 5.9 0.8 6.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2802) EspB PF05802.11 AAL62833.1 - 0.04 13.9 17.3 0.58 10.1 1.4 3.1 1 1 2 3 3 3 0 Enterobacterial EspB protein KfrA_N PF11740.8 AAL62833.1 - 0.041 14.6 12.4 0.94 10.2 3.0 3.6 1 1 2 3 3 3 0 Plasmid replication region DNA-binding N-term DUF4200 PF13863.6 AAL62833.1 - 0.044 14.2 25.7 0.38 11.2 14.9 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) BshC PF10079.9 AAL62833.1 - 0.045 12.5 14.0 0.2 10.4 6.5 2.2 1 1 1 2 2 2 0 Bacillithiol biosynthesis BshC FAM76 PF16046.5 AAL62833.1 - 0.047 13.0 15.8 0.39 10.0 2.7 2.3 1 1 1 2 2 2 0 FAM76 protein COG5 PF10392.9 AAL62833.1 - 0.061 13.5 13.4 0.18 12.0 2.9 2.7 1 1 1 2 2 2 0 Golgi transport complex subunit 5 MutS_IV PF05190.18 AAL62833.1 - 0.062 13.7 17.9 8 6.9 0.5 5.4 1 1 6 7 7 7 0 MutS family domain IV DUF2959 PF11172.8 AAL62833.1 - 0.064 13.4 14.4 7 6.7 4.3 3.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2959) RPW8 PF05659.11 AAL62833.1 - 0.065 12.9 15.0 0.68 9.6 2.7 3.6 1 1 3 4 4 4 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 ACCA PF03255.14 AAL62833.1 - 0.068 13.0 15.6 1.1 9.1 2.8 3.5 1 1 2 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit COG2 PF06148.11 AAL62833.1 - 0.072 13.2 17.1 17 5.5 2.1 4.4 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 V_ATPase_I PF01496.19 AAL62833.1 - 0.077 10.9 16.1 0.24 9.3 2.6 2.8 1 1 2 3 3 3 0 V-type ATPase 116kDa subunit family Prefoldin_2 PF01920.20 AAL62833.1 - 0.082 12.9 19.8 5.5 7.0 1.7 4.8 1 1 4 5 5 5 0 Prefoldin subunit Ku_C PF03730.14 AAL62833.1 - 0.082 13.6 13.0 5.4 7.8 3.4 3.9 1 1 1 2 2 2 0 Ku70/Ku80 C-terminal arm CorA PF01544.18 AAL62833.1 - 0.086 12.1 25.6 0.29 10.4 19.4 2.4 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein DUF885 PF05960.11 AAL62833.1 - 0.091 12.4 10.4 1.6 8.3 3.6 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF885) Rad50_zn_hook PF04423.14 AAL62833.1 - 0.093 12.6 16.6 62 3.5 0.2 7.5 1 1 5 7 7 7 0 Rad50 zinc hook motif Zwint PF15556.6 AAL62833.1 - 0.093 12.2 11.8 1 8.8 1.1 2.7 1 1 1 2 2 2 0 ZW10 interactor Peripla_BP_2 PF01497.18 AAL62833.1 - 0.097 12.2 11.6 7 6.1 1.2 3.8 1 1 3 4 4 4 0 Periplasmic binding protein Alpha-2-MRAP_C PF06401.11 AAL62833.1 - 0.097 12.6 16.8 0.43 10.5 4.3 3.1 1 1 2 3 3 3 0 Alpha-2-macroglobulin RAP, C-terminal domain CLZ PF16526.5 AAL62833.1 - 0.1 13.0 16.8 1.1 9.6 1.2 3.6 1 1 3 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels MIP-T3_C PF17749.1 AAL62833.1 - 0.1 12.6 31.1 0.83 9.6 4.0 3.7 1 1 2 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region E2R135 PF11570.8 AAL62833.1 - 0.1 12.9 12.4 0.23 11.7 0.8 3.7 1 1 2 4 4 4 0 Coiled-coil receptor-binding R-domain of colicin E2 LXG PF04740.12 AAL62833.1 - 0.11 12.2 17.1 2.3 7.9 4.5 2.8 1 1 1 2 2 2 0 LXG domain of WXG superfamily Nup88 PF10168.9 AAL62833.1 - 0.11 10.3 20.2 0.058 11.2 16.9 1.8 1 1 1 2 2 2 0 Nuclear pore component Zw10 PF06248.13 AAL62833.1 - 0.12 10.9 12.7 0.41 9.2 6.7 2.2 1 1 1 2 2 2 0 Centromere/kinetochore Zw10 DUF1640 PF07798.11 AAL62833.1 - 0.12 12.4 32.5 4.4 7.3 2.5 4.5 1 1 4 5 5 5 0 Protein of unknown function (DUF1640) Mce4_CUP1 PF11887.8 AAL62833.1 - 0.12 11.8 5.8 1.6 8.1 0.4 2.4 1 1 1 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative Phasin PF05597.11 AAL62833.1 - 0.12 12.3 18.9 6.6 6.7 6.7 3.5 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF2205 PF10224.9 AAL62833.1 - 0.12 12.3 21.4 0.6 10.1 2.6 4.5 1 1 3 4 4 4 0 Short coiled-coil protein DUF2730 PF10805.8 AAL62833.1 - 0.14 12.3 13.2 1.2 9.3 1.8 4.0 1 1 4 5 5 5 0 Protein of unknown function (DUF2730) DUF4618 PF15397.6 AAL62833.1 - 0.14 11.6 18.1 0.21 11.0 6.6 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4618) DHR10 PF18595.1 AAL62833.1 - 0.14 12.2 23.4 0.25 11.4 7.1 3.3 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain COG6 PF06419.11 AAL62833.1 - 0.14 10.3 15.7 0.33 9.1 2.6 3.2 1 1 2 3 3 3 0 Conserved oligomeric complex COG6 CHD5 PF04420.14 AAL62833.1 - 0.14 12.0 18.2 1.6 8.5 0.4 4.9 1 1 4 5 5 5 0 CHD5-like protein MtrG PF04210.13 AAL62833.1 - 0.16 11.9 21.2 7.8 6.4 1.7 6.0 1 1 3 4 4 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G TssO PF17561.2 AAL62833.1 - 0.16 12.1 17.7 4.7 7.3 10.4 3.9 1 1 1 2 2 2 0 Type VI secretion system, TssO GldM_N PF12081.8 AAL62833.1 - 0.17 12.0 11.5 0.3 11.2 2.7 2.4 1 1 1 2 2 2 0 GldM N-terminal domain CR6_interact PF10147.9 AAL62833.1 - 0.18 11.5 18.4 0.38 10.5 6.9 2.2 1 1 1 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Hemagglutinin PF00509.18 AAL62833.1 - 0.21 9.9 21.7 1.8 6.8 10.3 3.2 1 1 2 3 3 3 0 Haemagglutinin ArAE_2 PF10334.9 AAL62833.1 - 0.22 11.3 2.3 3.9 7.2 0.2 2.8 1 1 2 3 3 3 0 Aromatic acid exporter family member 2 T3SS_needle_F PF09392.10 AAL62833.1 - 0.23 11.7 3.9 39 4.5 0.1 4.2 2 2 3 5 5 4 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF UPF0242 PF06785.11 AAL62833.1 - 0.23 11.5 23.8 2.3 8.3 9.4 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus SlyX PF04102.12 AAL62833.1 - 0.23 12.1 22.3 5.4 7.7 0.6 4.8 1 1 2 3 3 3 0 SlyX FliJ PF02050.16 AAL62833.1 - 0.24 11.6 13.4 0.33 11.2 2.0 3.2 1 1 1 2 2 2 0 Flagellar FliJ protein SF-assemblin PF06705.11 AAL62833.1 - 0.26 10.6 31.4 1.1 8.6 21.7 2.1 1 1 1 2 2 2 0 SF-assemblin/beta giardin DUF3552 PF12072.8 AAL62833.1 - 0.3 10.5 29.3 0.42 10.0 9.8 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) DUF4527 PF15030.6 AAL62833.1 - 0.31 10.4 5.9 0.24 10.8 1.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4527) Alanine_zipper PF11839.8 AAL62833.1 - 0.34 11.3 14.0 41 4.6 2.2 6.9 1 1 4 5 5 5 0 Alanine-zipper, major outer membrane lipoprotein Fmp27_WPPW PF10359.9 AAL62833.1 - 0.35 9.6 22.7 5.8 5.7 1.7 2.9 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain APG6_N PF17675.1 AAL62833.1 - 0.37 11.3 15.5 1.5 9.3 7.0 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF4446 PF14584.6 AAL62833.1 - 0.37 10.8 16.3 4.5 7.3 3.2 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) DUF4208 PF13907.6 AAL62833.1 - 0.38 11.2 11.2 0.26 11.8 0.6 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4208) HAUS6_N PF14661.6 AAL62833.1 - 0.4 10.2 16.6 9.4e+02 -0.8 16.6 2.4 1 1 0 1 1 0 0 HAUS augmin-like complex subunit 6 N-terminus Fez1 PF06818.15 AAL62833.1 - 0.41 11.1 18.1 8.9 6.7 18.1 2.3 1 1 0 1 1 1 0 Fez1 DUF5098 PF17023.5 AAL62833.1 - 0.46 9.4 16.7 0.031 13.2 1.6 3.3 1 1 3 4 4 4 0 Domain of unknown function (DUF5098) DUF1848 PF08902.11 AAL62833.1 - 0.47 10.1 6.0 1.5 8.4 5.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1848) DUF5446 PF17522.2 AAL62833.1 - 0.56 10.4 30.7 7.6 6.8 3.2 5.7 1 1 5 6 6 5 0 Family of unknown function (DUF5446) AvrM-A PF18241.1 AAL62833.1 - 0.59 10.5 16.3 2.2 8.7 6.8 3.1 1 1 1 2 2 2 0 Flax-rust effector AvrM-A DUF1515 PF07439.11 AAL62833.1 - 0.6 10.2 23.7 3.5 7.7 2.7 4.0 1 1 4 5 5 5 0 Protein of unknown function (DUF1515) LMBR1 PF04791.16 AAL62833.1 - 0.6 8.9 19.1 0.45 9.4 12.9 2.0 1 1 1 2 2 2 0 LMBR1-like membrane protein FlaC_arch PF05377.11 AAL62833.1 - 0.68 10.4 25.3 2.3 8.7 0.4 5.8 1 1 2 3 3 2 0 Flagella accessory protein C (FlaC) HrpB7 PF09486.10 AAL62833.1 - 0.68 10.3 29.6 0.64 10.4 5.7 4.0 1 1 2 3 3 2 0 Bacterial type III secretion protein (HrpB7) Peptidase_M75 PF09375.10 AAL62833.1 - 0.72 9.3 12.5 3.3 7.1 0.5 3.5 1 1 3 4 4 4 0 Imelysin Prefoldin PF02996.17 AAL62833.1 - 0.8 9.6 21.7 2.1 8.3 0.6 4.6 1 1 3 4 4 4 0 Prefoldin subunit CENP-H PF05837.12 AAL62833.1 - 0.82 10.1 19.2 1.5 9.3 6.8 2.8 1 1 1 2 2 2 0 Centromere protein H (CENP-H) p450 PF00067.22 AAL62833.1 - 0.85 8.3 6.4 0.35 9.6 1.1 2.2 1 1 1 2 2 2 0 Cytochrome P450 Pullulanase_Ins PF18494.1 AAL62833.1 - 0.95 10.0 11.5 5.2 7.6 0.5 4.3 1 1 2 4 4 3 0 Pullulanase Ins domain DUF489 PF04356.12 AAL62833.1 - 1 9.4 7.7 3.6 7.5 0.5 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF489) Fusion_gly PF00523.18 AAL62833.1 - 1 7.5 10.5 0.29 9.3 0.4 2.8 1 1 2 3 3 3 0 Fusion glycoprotein F0 Vicilin_N PF04702.12 AAL62833.1 - 1.1 9.1 7.5 0.48 10.2 2.8 2.0 1 1 1 2 2 2 0 Vicilin N terminal region EDR1 PF14381.6 AAL62833.1 - 1.1 8.9 6.8 9 6.0 0.9 2.6 1 1 2 3 3 3 0 Ethylene-responsive protein kinase Le-CTR1 FemAB PF02388.16 AAL62833.1 - 1.2 7.9 19.6 0.21 10.5 1.8 3.0 1 1 2 3 3 3 0 FemAB family TMCO5 PF14992.6 AAL62833.1 - 1.2 8.6 20.5 1.1 8.8 16.9 2.5 1 1 1 2 2 2 0 TMCO5 family Pex26 PF07163.12 AAL62833.1 - 1.3 8.2 4.1 5.1 6.3 0.8 2.2 1 1 1 2 2 2 0 Pex26 protein HU-CCDC81_bac_2 PF18175.1 AAL62833.1 - 1.4 8.8 16.2 55 3.7 0.1 5.8 3 2 3 6 6 6 0 CCDC81-like prokaryotic HU domain 2 DUF4665 PF15679.5 AAL62833.1 - 1.6 9.4 15.0 2.5 8.8 0.7 3.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4665) Syntaxin PF00804.25 AAL62833.1 - 1.9 8.1 21.9 4 7.1 7.6 2.8 1 1 1 2 2 2 0 Syntaxin ZapA PF05164.13 AAL62833.1 - 2 8.9 16.8 0.64 10.5 0.7 4.9 1 1 2 3 3 2 0 Cell division protein ZapA DASH_Duo1 PF08651.10 AAL62833.1 - 2 8.2 18.0 2.8 7.8 1.2 4.7 1 1 3 4 4 4 0 DASH complex subunit Duo1 DUF1759 PF03564.15 AAL62833.1 - 2.1 8.3 15.3 0.45 10.4 5.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1759) DUF1845 PF08900.11 AAL62833.1 - 2.2 7.9 11.5 13 5.5 0.9 4.1 1 1 3 4 4 4 0 Domain of unknown function (DUF1845) GrpE PF01025.19 AAL62833.1 - 2.3 7.8 18.7 16 5.1 1.3 3.0 1 1 2 3 3 3 0 GrpE DUF883 PF05957.13 AAL62833.1 - 2.7 8.6 15.2 6.2 7.5 3.3 3.6 2 1 2 4 4 3 0 Bacterial protein of unknown function (DUF883) SOAR PF16533.5 AAL62833.1 - 3 7.9 19.2 5.3 7.1 0.6 5.2 1 1 4 5 5 5 0 STIM1 Orai1-activating region Tweety PF04906.13 AAL62833.1 - 3.2 6.3 6.2 9 4.8 2.6 2.2 1 1 2 3 3 3 0 Tweety DUF4226 PF10774.9 AAL62833.1 - 3.2 8.1 16.1 11 6.3 1.0 4.1 1 1 3 4 4 4 0 Domain of unknown function (DUF4226) Syntaxin-6_N PF09177.11 AAL62833.1 - 3.3 8.3 17.9 40 4.8 3.3 3.4 1 1 1 2 2 1 0 Syntaxin 6, N-terminal FAP206 PF12018.8 AAL62833.1 - 3.7 7.0 8.9 70 2.8 8.6 2.8 1 1 1 2 2 2 0 Domain of unknown function STAT_alpha PF01017.20 AAL62833.1 - 3.8 7.4 15.8 2.6e+02 1.4 15.8 2.5 1 1 0 1 1 1 0 STAT protein, all-alpha domain NPA PF16469.5 AAL62833.1 - 3.8 8.1 11.5 9.1 6.9 0.7 4.1 1 1 3 4 4 4 0 Nematode polyprotein allergen ABA-1 DUF5082 PF16888.5 AAL62833.1 - 4.1 7.7 28.3 22 5.4 21.0 3.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) 5_nucleotid PF05761.14 AAL62833.1 - 4.2 6.2 13.4 13 4.5 6.4 2.3 1 1 1 2 2 2 0 5' nucleotidase family YojJ PF10372.9 AAL62833.1 - 4.4 7.5 12.9 8.9 6.5 0.6 4.8 1 1 3 4 4 3 0 Bacterial membrane-spanning protein N-terminus AI-2E_transport PF01594.16 AAL62833.1 - 5.1 6.2 3.9 15 4.6 1.4 2.5 1 1 1 2 2 2 0 AI-2E family transporter FlxA PF14282.6 AAL62833.1 - 5.4 7.1 20.5 7.3 6.7 3.8 3.5 1 1 2 3 3 3 0 FlxA-like protein DUF724 PF05266.14 AAL62833.1 - 5.8 6.7 17.3 4.5 7.1 6.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF4140 PF13600.6 AAL62833.1 - 5.9 7.4 25.3 1.8e+04 -13.1 25.3 4.8 1 1 0 1 1 0 0 N-terminal domain of unknown function (DUF4140) DASH_Spc19 PF08287.11 AAL62833.1 - 6.3 6.7 22.4 15 5.4 4.2 3.5 1 1 2 3 3 3 0 Spc19 Coiled-coil_56 PF09813.9 AAL62833.1 - 6.6 6.8 11.5 32 4.6 0.2 4.0 1 1 4 5 5 5 0 Coiled-coil domain-containing protein 56 Med22 PF06179.12 AAL62833.1 - 6.8 7.0 21.6 15 5.8 1.1 5.0 1 1 4 5 5 5 0 Surfeit locus protein 5 subunit 22 of Mediator complex Cortex-I_coil PF09304.10 AAL62833.1 - 7.3 6.9 26.9 0.91 9.8 2.9 4.6 1 1 3 4 4 3 0 Cortexillin I, coiled coil Translin PF01997.16 AAL62833.1 - 7.4 6.5 17.4 8.7 6.3 2.5 3.0 1 1 2 3 3 3 0 Translin family Alb1 PF09135.11 AAL62833.1 - 8.5 7.3 16.7 6 7.8 6.1 2.4 1 1 1 2 2 2 0 Alb1 DSX_dimer PF08828.10 AAL62833.1 - 9.8 5.9 20.1 7.1 6.4 0.5 6.5 1 1 5 6 6 5 0 Doublesex dimerisation domain MRF_C1 PF13887.6 AAL62833.1 - 9.9 5.4 22.6 3.4 6.9 0.1 7.6 2 2 4 8 8 8 0 Myelin gene regulatory factor -C-terminal domain 1 KorB PF08535.10 AAL62836.1 - 0.038 14.0 0.2 0.17 11.9 0.1 2.1 2 0 0 2 2 2 0 KorB domain DUF2225 PF09986.9 AAL62837.1 - 0.42 10.3 1.8 0.56 9.9 0.8 1.6 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) ATPase_2 PF01637.18 AAL62839.1 - 1.1e-65 221.9 0.0 1.3e-65 221.6 0.0 1.1 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA PF00004.29 AAL62839.1 - 0.00059 20.3 0.0 0.0011 19.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AAL62839.1 - 0.0043 17.4 0.2 0.01 16.3 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 AAL62839.1 - 0.0082 16.4 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 AAL62839.1 - 0.011 15.5 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 AAL62839.1 - 0.024 14.6 0.1 0.77 9.7 0.1 2.8 2 1 0 2 2 2 0 NACHT domain AAA_33 PF13671.6 AAL62839.1 - 0.032 14.4 0.0 0.059 13.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 AAL62839.1 - 0.049 14.0 0.0 0.081 13.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase RNA12 PF10443.9 AAL62839.1 - 0.084 11.6 0.1 2 7.1 0.0 2.5 2 1 1 3 3 3 0 RNA12 protein His_Phos_1 PF00300.22 AAL62840.1 - 4.8e-11 42.7 0.2 9.6e-10 38.5 0.2 2.0 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) HSBP1 PF06825.12 AAL62841.1 - 3.5e-08 33.2 17.0 0.084 12.7 0.4 4.6 1 1 3 4 4 4 4 Heat shock factor binding protein 1 DUF948 PF06103.11 AAL62841.1 - 5.3e-07 29.8 6.6 0.00073 19.7 1.0 2.6 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 AAL62841.1 - 1.6e-05 25.0 8.1 2.4e-05 24.3 2.8 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) Apolipoprotein PF01442.18 AAL62841.1 - 6.9e-05 22.8 3.5 9.7e-05 22.3 3.5 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain V_ATPase_I PF01496.19 AAL62841.1 - 0.00019 19.5 3.7 0.00022 19.3 3.7 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family CdvA PF18822.1 AAL62841.1 - 0.00026 20.8 6.6 0.00028 20.7 4.3 2.3 1 1 0 1 1 1 1 CdvA-like coiled-coil domain MCPsignal PF00015.21 AAL62841.1 - 0.00059 19.7 3.1 0.0053 16.6 1.8 2.1 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Baculo_PEP_C PF04513.12 AAL62841.1 - 0.00082 19.4 3.9 0.0017 18.4 3.4 1.9 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Phage_Mu_Gam PF07352.12 AAL62841.1 - 0.00089 19.2 3.5 0.0011 18.8 2.5 1.7 1 1 0 1 1 1 1 Bacteriophage Mu Gam like protein Zw10 PF06248.13 AAL62841.1 - 0.0011 17.6 3.6 0.0012 17.5 3.6 1.2 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 TMF_TATA_bd PF12325.8 AAL62841.1 - 0.002 18.3 5.2 0.0031 17.7 3.2 1.9 1 1 1 2 2 2 1 TATA element modulatory factor 1 TATA binding IFT57 PF10498.9 AAL62841.1 - 0.0023 17.0 3.7 0.0027 16.7 0.8 1.8 1 1 0 1 1 1 1 Intra-flagellar transport protein 57 DUF2959 PF11172.8 AAL62841.1 - 0.0027 17.9 0.6 0.0031 17.7 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2959) Mt_ATP-synt_D PF05873.12 AAL62841.1 - 0.0031 17.4 1.2 0.0046 16.8 1.2 1.3 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Exonuc_VII_L PF02601.15 AAL62841.1 - 0.0033 17.0 1.1 0.0037 16.9 1.1 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit KxDL PF10241.9 AAL62841.1 - 0.0033 17.7 7.7 0.56 10.5 0.5 3.0 1 1 2 3 3 3 2 Uncharacterized conserved protein DUF148 PF02520.17 AAL62841.1 - 0.0035 17.4 1.9 0.0035 17.4 1.9 2.2 1 1 1 2 2 2 1 Domain of unknown function DUF148 DUF4455 PF14643.6 AAL62841.1 - 0.0037 16.0 3.5 0.0047 15.6 3.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4455) MscS_porin PF12795.7 AAL62841.1 - 0.004 16.7 1.2 0.0053 16.3 1.2 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain XhlA PF10779.9 AAL62841.1 - 0.0043 17.2 11.1 0.17 12.1 4.0 2.5 1 1 1 2 2 2 2 Haemolysin XhlA NPV_P10 PF05531.12 AAL62841.1 - 0.0047 17.4 6.9 0.081 13.4 0.6 3.1 1 1 2 3 3 3 2 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 AAL62841.1 - 0.0048 16.9 2.8 0.041 13.9 1.0 2.2 1 1 1 2 2 2 2 Laminin Domain II Phage_GPO PF05929.11 AAL62841.1 - 0.0051 16.5 0.9 0.0061 16.2 0.9 1.1 1 0 0 1 1 1 1 Phage capsid scaffolding protein (GPO) serine peptidase AAA_13 PF13166.6 AAL62841.1 - 0.0051 15.5 3.1 0.0052 15.5 3.1 1.1 1 0 0 1 1 1 1 AAA domain DUF1351 PF07083.11 AAL62841.1 - 0.0055 16.5 5.3 0.46 10.2 1.5 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF1351) BLI1 PF17324.2 AAL62841.1 - 0.0055 17.4 4.6 0.098 13.3 0.4 2.2 1 1 1 2 2 2 1 BLOC-1 interactor 1 RPW8 PF05659.11 AAL62841.1 - 0.0058 16.3 7.3 0.15 11.7 0.5 3.0 1 1 2 3 3 3 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF3450 PF11932.8 AAL62841.1 - 0.006 15.9 3.4 0.0081 15.5 3.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) ApoLp-III PF07464.11 AAL62841.1 - 0.0075 16.4 2.1 0.012 15.7 2.1 1.6 1 1 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) DHC_N1 PF08385.12 AAL62841.1 - 0.008 14.9 4.3 0.009 14.7 4.3 1.1 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 Sec5 PF15469.6 AAL62841.1 - 0.0093 15.8 6.7 0.014 15.2 5.5 1.9 1 1 1 2 2 2 1 Exocyst complex component Sec5 CorA PF01544.18 AAL62841.1 - 0.0094 15.3 8.2 0.013 14.9 7.6 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Prefoldin PF02996.17 AAL62841.1 - 0.011 15.6 6.1 0.27 11.1 0.3 2.9 1 1 2 3 3 3 0 Prefoldin subunit FliD_C PF07195.12 AAL62841.1 - 0.014 14.9 3.9 1 8.7 0.6 2.2 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Syntaxin PF00804.25 AAL62841.1 - 0.015 15.0 9.8 0.1 12.3 7.7 2.0 1 1 1 2 2 2 0 Syntaxin T3SSipB PF16535.5 AAL62841.1 - 0.017 15.6 0.8 0.067 13.7 0.6 1.9 1 1 1 2 2 2 0 Type III cell invasion protein SipB GCN5L1 PF06320.13 AAL62841.1 - 0.017 15.2 2.6 0.43 10.7 0.3 2.2 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) ABC_tran_CTD PF16326.5 AAL62841.1 - 0.018 15.3 2.6 0.08 13.2 0.8 2.5 1 1 2 3 3 3 0 ABC transporter C-terminal domain KMP11 PF03037.16 AAL62841.1 - 0.019 15.8 3.3 0.16 12.8 0.4 2.7 1 1 0 1 1 1 0 Kinetoplastid membrane protein 11 TPR_MLP1_2 PF07926.12 AAL62841.1 - 0.019 15.0 1.0 0.04 14.0 0.5 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Seryl_tRNA_N PF02403.22 AAL62841.1 - 0.023 14.9 7.4 0.02 15.1 5.3 1.8 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Fib_alpha PF08702.10 AAL62841.1 - 0.029 14.5 6.7 0.053 13.7 6.4 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF16 PF01519.16 AAL62841.1 - 0.032 14.7 8.6 0.041 14.4 6.3 1.9 1 1 1 2 2 2 0 Protein of unknown function DUF16 HAUS6_N PF14661.6 AAL62841.1 - 0.033 13.7 1.2 0.038 13.6 1.2 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus YkyA PF10368.9 AAL62841.1 - 0.033 13.8 6.8 0.23 11.1 6.7 2.0 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein Sec34 PF04136.15 AAL62841.1 - 0.035 14.0 2.9 0.2 11.6 0.5 2.3 1 1 2 3 3 3 0 Sec34-like family Mer2 PF09074.10 AAL62841.1 - 0.035 13.9 6.6 0.059 13.2 6.6 1.5 1 1 0 1 1 1 0 Mer2 BLOC1_2 PF10046.9 AAL62841.1 - 0.037 14.3 4.0 0.069 13.5 2.4 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SHE3 PF17078.5 AAL62841.1 - 0.037 13.8 5.6 0.061 13.0 5.5 1.4 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 TBCC_N PF16752.5 AAL62841.1 - 0.042 14.3 3.6 0.2 12.1 3.3 2.1 1 1 1 2 2 2 0 Tubulin-specific chaperone C N-terminal domain HR1 PF02185.16 AAL62841.1 - 0.043 13.9 2.7 0.35 11.0 2.6 2.5 1 1 0 1 1 1 0 Hr1 repeat Tropomyosin_1 PF12718.7 AAL62841.1 - 0.047 13.9 3.6 0.062 13.4 3.6 1.4 1 0 0 1 1 1 0 Tropomyosin like ISG65-75 PF11727.8 AAL62841.1 - 0.059 12.6 1.2 0.067 12.4 1.2 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein TMPIT PF07851.13 AAL62841.1 - 0.06 12.6 1.0 0.075 12.3 1.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF4041 PF13250.6 AAL62841.1 - 0.061 13.2 5.0 1.1 9.2 0.5 3.2 2 1 2 4 4 3 0 Domain of unknown function (DUF4041) SL4P PF17618.2 AAL62841.1 - 0.069 13.2 2.0 2.2 8.4 0.1 2.6 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein MADF_DNA_bdg PF10545.9 AAL62841.1 - 0.074 13.4 0.9 0.11 12.8 0.5 1.6 1 1 1 2 2 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like APG17 PF04108.12 AAL62841.1 - 0.075 12.1 6.6 0.12 11.5 6.6 1.4 1 1 0 1 1 1 0 Autophagy protein Apg17 Transcrip_act PF04949.13 AAL62841.1 - 0.079 12.8 7.7 0.3 11.0 7.6 1.9 1 1 0 1 1 1 0 Transcriptional activator FAM76 PF16046.5 AAL62841.1 - 0.1 11.9 3.1 0.13 11.6 3.1 1.1 1 0 0 1 1 1 0 FAM76 protein Matrilin_ccoil PF10393.9 AAL62841.1 - 0.1 12.5 1.6 15 5.5 0.1 3.4 3 1 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin SlyX PF04102.12 AAL62841.1 - 0.11 13.1 7.9 0.52 11.0 0.6 3.1 1 1 2 3 3 3 0 SlyX Spectrin PF00435.21 AAL62841.1 - 0.12 12.8 2.6 0.4 11.2 2.0 2.3 1 1 0 1 1 1 0 Spectrin repeat Phasin PF05597.11 AAL62841.1 - 0.14 12.2 3.2 0.46 10.5 2.9 2.0 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DinI PF06183.13 AAL62841.1 - 0.14 12.5 1.4 10 6.5 0.1 3.0 2 1 1 3 3 2 0 DinI-like family DUF4200 PF13863.6 AAL62841.1 - 0.14 12.5 8.8 0.25 11.7 8.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) MRP-L51 PF10244.9 AAL62841.1 - 0.15 12.3 1.1 5.6 7.2 0.1 2.4 1 1 1 2 2 2 0 Mitochondrial ribosomal subunit DUF4446 PF14584.6 AAL62841.1 - 0.16 12.0 3.2 0.49 10.4 2.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) PMC2NT PF08066.12 AAL62841.1 - 0.16 12.7 3.8 0.29 11.9 1.3 2.4 1 1 1 2 2 2 0 PMC2NT (NUC016) domain Snapin_Pallidin PF14712.6 AAL62841.1 - 0.17 12.3 9.3 3.4 8.2 1.9 2.6 1 1 1 2 2 2 0 Snapin/Pallidin DUF3782 PF12644.7 AAL62841.1 - 0.19 11.9 5.6 1.3 9.2 0.7 3.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3782) Fzo_mitofusin PF04799.13 AAL62841.1 - 0.2 11.2 2.4 0.64 9.5 2.3 1.9 1 1 0 1 1 1 0 fzo-like conserved region HIP1_clath_bdg PF16515.5 AAL62841.1 - 0.2 12.3 4.1 0.17 12.5 2.8 1.6 2 1 0 2 2 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 HSCB_C PF07743.13 AAL62841.1 - 0.27 11.8 9.6 11 6.6 9.6 2.7 1 1 0 1 1 1 0 HSCB C-terminal oligomerisation domain DHR10 PF18595.1 AAL62841.1 - 0.27 11.3 6.0 0.93 9.6 5.6 2.0 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain TssO PF17561.2 AAL62841.1 - 0.35 11.0 7.4 12 6.0 7.4 2.4 1 1 0 1 1 1 0 Type VI secretion system, TssO DUF2203 PF09969.9 AAL62841.1 - 0.39 11.5 3.6 1.6 9.4 3.6 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) YabA PF06156.13 AAL62841.1 - 0.39 11.4 2.7 0.77 10.4 1.9 1.9 1 1 0 1 1 1 0 Initiation control protein YabA COG2 PF06148.11 AAL62841.1 - 0.39 10.8 4.2 0.61 10.2 0.8 2.2 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 LUC7 PF03194.15 AAL62841.1 - 0.4 10.3 5.4 0.77 9.4 5.3 1.6 1 1 1 2 2 2 0 LUC7 N_terminus Prefoldin_3 PF13758.6 AAL62841.1 - 0.5 10.4 9.3 6.3 6.9 7.1 3.2 1 1 1 2 2 2 0 Prefoldin subunit Uds1 PF15456.6 AAL62841.1 - 0.55 10.4 4.4 3 8.0 1.7 2.6 1 1 1 2 2 2 0 Up-regulated During Septation Noelin-1 PF12308.8 AAL62841.1 - 0.6 10.1 2.8 1.4 8.9 0.5 2.2 1 1 1 2 2 2 0 Neurogenesis glycoprotein TRPM_tetra PF16519.5 AAL62841.1 - 0.66 10.1 6.8 1.5 9.0 0.3 3.4 1 1 2 3 3 3 0 Tetramerisation domain of TRPM Alanine_zipper PF11839.8 AAL62841.1 - 0.74 10.2 3.9 41 4.6 0.1 3.2 1 1 1 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein Hemagglutinin PF00509.18 AAL62841.1 - 0.79 8.0 6.7 0.67 8.3 3.8 1.9 1 1 1 2 2 2 0 Haemagglutinin MtrG PF04210.13 AAL62841.1 - 1.2 9.0 4.9 38 4.2 0.9 3.3 1 1 2 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF4795 PF16043.5 AAL62841.1 - 1.6 8.3 9.5 4 7.0 9.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) zf-C4H2 PF10146.9 AAL62841.1 - 3.8 7.8 6.8 4.8 7.4 6.8 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein PaREP1 PF05942.11 AAL62842.1 - 3.7e-31 107.4 3.4 1.2e-30 105.8 0.5 2.0 2 0 0 2 2 2 2 Archaeal PaREP1/PaREP8 family Asp_protease_2 PF13650.6 AAL62843.1 - 7.7e-06 26.5 0.1 1.9e-05 25.2 0.1 1.6 1 1 1 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 AAL62843.1 - 9.5e-06 26.1 0.0 1.4e-05 25.6 0.0 1.4 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 AAL62843.1 - 0.013 15.8 0.0 0.077 13.3 0.0 1.9 1 1 0 1 1 1 0 Retroviral aspartyl protease Putative_G5P PF17426.2 AAL62843.1 - 0.02 15.0 0.0 0.027 14.6 0.0 1.4 1 1 0 1 1 1 0 Putative Gamma DNA binding protein G5P ATPase_2 PF01637.18 AAL62845.1 - 3.1e-16 60.0 0.0 4e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Glycos_transf_1 PF00534.20 AAL62849.1 - 1.2e-25 90.0 0.0 2.1e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAL62849.1 - 1.5e-18 67.5 0.0 2.3e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AAL62849.1 - 7.1e-06 26.3 0.0 1.7e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAL62849.1 - 0.00036 20.6 0.0 0.002 18.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase Family 4 ALG11_N PF15924.5 AAL62849.1 - 0.0015 18.6 0.1 0.0039 17.3 0.0 1.7 2 0 0 2 2 2 1 ALG11 mannosyltransferase N-terminus Epimerase_2 PF02350.19 AAL62849.1 - 0.0077 15.1 0.0 0.031 13.1 0.0 1.7 1 1 1 2 2 2 1 UDP-N-acetylglucosamine 2-epimerase Glycos_transf_1 PF00534.20 AAL62850.1 - 1.1e-10 41.3 0.0 1.9e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAL62850.1 - 2.1e-09 37.9 0.1 3.4e-09 37.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AAL62850.1 - 6e-08 33.0 0.0 1.1e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3880 PF12996.7 AAL62850.1 - 7.3e-06 26.0 0.1 2.3e-05 24.4 0.1 1.9 1 0 0 1 1 1 1 DUF based on E. rectale Gene description (DUF3880) Glyco_transf_4 PF13439.6 AAL62850.1 - 3.6e-05 23.8 0.0 6.6e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 AAL62851.1 - 1.7e-21 76.5 0.0 3.2e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAL62851.1 - 1.6e-14 54.5 0.0 3e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AAL62852.1 - 3.6e-12 46.2 0.0 7.1e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAL62852.1 - 4e-06 27.3 0.0 8e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AAL62852.1 - 0.00094 19.5 0.0 0.002 18.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAL62852.1 - 0.036 14.1 0.1 0.091 12.8 0.1 1.7 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Glycos_transf_2 PF00535.26 AAL62853.1 - 2.8e-14 53.3 0.1 5.9e-14 52.2 0.1 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 AAL62853.1 - 1.6e-07 31.1 0.2 3.6e-06 26.7 0.2 2.2 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 AAL62853.1 - 3.5e-06 27.1 0.0 0.057 13.3 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 AAL62853.1 - 2.9e-05 23.6 0.0 0.00025 20.5 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 AAL62853.1 - 0.00013 21.9 0.1 0.00023 21.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Anp1 PF03452.14 AAL62853.1 - 0.04 13.3 0.1 0.066 12.6 0.1 1.3 1 0 0 1 1 1 0 Anp1 Glycos_transf_2 PF00535.26 AAL62854.1 - 0.0072 16.1 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Amino_oxidase PF01593.24 AAL62855.1 - 1.5e-11 44.3 0.1 3e-09 36.7 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 AAL62855.1 - 2.4e-05 24.5 0.2 7.3e-05 22.9 0.2 1.9 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AAL62855.1 - 0.0055 16.3 0.1 0.065 12.8 0.1 2.4 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 AAL62855.1 - 0.19 10.9 0.0 0.33 10.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DnaG_DnaB_bind PF08278.11 AAL62856.1 - 0.023 15.3 0.9 0.045 14.3 0.9 1.5 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding baeRF_family3 PF18845.1 AAL62856.1 - 0.044 14.0 2.5 0.59 10.4 1.1 2.6 2 1 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 3 PDDEXK_10 PF07788.11 AAL62856.1 - 0.046 13.7 0.5 0.046 13.7 0.5 1.6 2 0 0 2 2 2 0 PD-(D/E)XK nuclease superfamily Bap31_Bap29_C PF18035.1 AAL62856.1 - 0.091 12.8 0.1 0.29 11.2 0.0 1.8 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain ATPgrasp_YheCD PF14398.6 AAL62856.1 - 0.093 12.0 0.1 0.33 10.2 0.0 1.8 1 1 1 2 2 2 0 YheC/D like ATP-grasp Apolipoprotein PF01442.18 AAL62856.1 - 0.11 12.4 4.6 0.21 11.4 4.6 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain PSK_trans_fac PF07704.11 AAL62856.1 - 4.7 8.0 13.2 1.4e+02 3.3 13.2 2.8 1 1 0 1 1 1 0 Rv0623-like transcription factor Ubiq_cyt_C_chap PF03981.12 AAL62857.1 - 0.038 14.1 0.2 0.039 14.0 0.2 1.1 1 0 0 1 1 1 0 Ubiquinol-cytochrome C chaperone PSK_trans_fac PF07704.11 AAL62857.1 - 0.073 13.8 2.2 0.078 13.7 2.2 1.2 1 0 0 1 1 1 0 Rv0623-like transcription factor HU-DNA_bdg PF14848.6 AAL62857.1 - 0.078 13.0 0.1 0.09 12.8 0.1 1.1 1 0 0 1 1 1 0 DNA-binding domain Hypoth_Ymh PF09509.10 AAL62857.1 - 0.086 12.7 0.2 0.096 12.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (Hypoth_ymh) DUF3782 PF12644.7 AAL62858.1 - 0.00038 20.6 0.1 0.00038 20.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3782) PDDEXK_10 PF07788.11 AAL62859.1 - 5.7e-11 42.2 2.1 7.8e-11 41.8 2.1 1.2 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily AA_permease_2 PF13520.6 AAL62861.1 - 4.7e-39 134.4 41.7 1.1e-38 133.2 41.5 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 AAL62861.1 - 7.6e-25 87.4 41.6 1.1e-24 86.9 41.6 1.1 1 0 0 1 1 1 1 Amino acid permease PaREP1 PF05942.11 AAL62864.1 - 5.2e-27 94.0 2.0 6.3e-27 93.8 2.0 1.1 1 0 0 1 1 1 1 Archaeal PaREP1/PaREP8 family DUF4518 PF15008.6 AAL62864.1 - 0.15 11.2 0.0 0.18 11.0 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) NUDIX PF00293.28 AAL62865.1 - 2.2e-15 56.9 0.0 3.7e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain ZnuA PF01297.17 AAL62866.1 - 0.0023 17.4 0.0 0.0032 16.9 0.0 1.3 1 1 0 1 1 1 1 Zinc-uptake complex component A periplasmic Trp_oprn_chp PF09534.10 AAL62866.1 - 3.8 7.3 9.4 1.3 8.8 3.6 2.3 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Na_Ca_ex PF01699.24 AAL62867.1 - 6.3e-14 52.2 25.6 8e-08 32.4 7.8 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Phage_holin_3_6 PF07332.11 AAL62868.1 - 6.4e-05 23.0 2.8 8.2e-05 22.6 2.8 1.2 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III DUF4131 PF13567.6 AAL62868.1 - 0.042 13.5 0.2 0.046 13.4 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF4307 PF14155.6 AAL62868.1 - 0.083 12.7 0.9 1.5 8.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) Topo-VIb_trans PF09239.11 AAL62868.1 - 0.097 12.5 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Topoisomerase VI B subunit, transducer HemY_N PF07219.13 AAL62868.1 - 0.3 11.3 4.0 0.41 10.9 3.7 1.5 1 1 0 1 1 1 0 HemY protein N-terminus Cation_efflux PF01545.21 AAL62869.1 - 1.4e-32 113.0 14.6 1.7e-32 112.8 14.6 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 AAL62869.1 - 1.9e-21 75.9 1.7 3.4e-21 75.1 1.7 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter IGPS PF00218.21 AAL62870.1 - 3.8e-52 177.0 0.0 5.1e-52 176.6 0.0 1.2 1 1 0 1 1 1 1 Indole-3-glycerol phosphate synthase His_biosynth PF00977.21 AAL62870.1 - 5.8e-05 22.7 0.0 0.0003 20.3 0.0 1.8 1 1 1 2 2 2 1 Histidine biosynthesis protein FMN_dh PF01070.18 AAL62870.1 - 0.0036 16.4 0.1 0.0091 15.1 0.0 1.5 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Ferritin PF00210.24 AAL62870.1 - 0.032 14.2 0.0 0.056 13.4 0.0 1.4 1 0 0 1 1 1 0 Ferritin-like domain Vut_1 PF02592.15 AAL62871.1 - 1.7e-29 103.1 8.9 1.7e-29 103.1 8.9 1.7 2 0 0 2 2 2 1 Putative vitamin uptake transporter BacA PF02673.18 AAL62872.1 - 5.6e-42 144.2 21.6 6.6e-42 144.0 21.6 1.0 1 0 0 1 1 1 1 Bacitracin resistance protein BacA Sugar_transport PF06800.12 AAL62872.1 - 3.5e-05 23.3 14.4 0.009 15.4 3.9 2.1 1 1 1 2 2 2 2 Sugar transport protein DUF5472 PF17566.2 AAL62872.1 - 4.4 7.3 5.6 2 8.4 0.7 2.7 1 1 1 2 2 2 0 Family of unknown function (DUF5472) H2O2_YaaD PF03883.14 AAL62873.1 - 0.00075 19.1 0.0 0.00082 18.9 0.0 1.1 1 0 0 1 1 1 1 Peroxide stress protein YaaA Radical_SAM PF04055.21 AAL62874.1 - 1.4e-26 93.9 0.0 3.1e-26 92.7 0.0 1.6 1 1 1 2 2 2 1 Radical SAM superfamily SPASM PF13186.6 AAL62874.1 - 1.8e-09 38.0 0.1 4.4e-09 36.7 0.1 1.6 1 0 0 1 1 1 1 Iron-sulfur cluster-binding domain Fer4_14 PF13394.6 AAL62874.1 - 3.9e-07 30.2 0.0 8.8e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 AAL62874.1 - 7.8e-07 29.4 0.0 1.8e-06 28.3 0.0 1.6 2 0 0 2 2 2 1 4Fe-4S single cluster domain Glyco_hydro_97 PF10566.9 AAL62874.1 - 0.004 16.5 0.0 0.96 8.7 0.0 2.2 1 1 0 2 2 2 2 Glycoside hydrolase 97 gag_pre-integrs PF13976.6 AAL62874.1 - 0.012 15.4 0.1 0.021 14.7 0.1 1.4 1 0 0 1 1 1 0 GAG-pre-integrase domain AP_endonuc_2 PF01261.24 AAL62874.1 - 0.033 13.6 0.1 1.6 8.2 0.0 2.5 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel Porphobil_deam PF01379.20 AAL62875.1 - 1.9e-61 207.2 0.0 2.3e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 AAL62875.1 - 5.8e-06 26.6 0.1 1.2e-05 25.6 0.1 1.6 1 1 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain UPF0767 PF15990.5 AAL62875.1 - 0.14 12.3 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 UPF0767 family AsnC_trans_reg2 PF17805.1 AAL62876.1 - 1e-35 121.7 0.3 4.8e-19 68.3 0.0 2.8 3 0 0 3 3 3 2 AsnC-like ligand binding domain HTH_AsnC-type PF13404.6 AAL62876.1 - 0.00016 21.4 0.0 0.94 9.4 0.0 2.7 2 0 0 2 2 2 2 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 AAL62876.1 - 0.021 14.4 0.4 0.092 12.3 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding ALAD PF00490.21 AAL62877.1 - 1.2e-139 464.9 0.0 1.4e-139 464.7 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase PEP_mutase PF13714.6 AAL62877.1 - 0.038 13.4 1.4 0.53 9.7 0.1 2.7 2 2 1 3 3 3 0 Phosphoenolpyruvate phosphomutase NAD_binding_7 PF13241.6 AAL62878.1 - 3e-19 69.4 0.0 6.1e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding CysG_dimeriser PF10414.9 AAL62878.1 - 0.00011 21.9 0.1 0.00028 20.6 0.1 1.7 1 0 0 1 1 1 1 Sirohaem synthase dimerisation region AlaDh_PNT_C PF01262.21 AAL62878.1 - 0.0061 15.9 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 AAL62878.1 - 0.0082 16.7 0.2 0.021 15.3 0.2 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rossmann-like PF10727.9 AAL62878.1 - 0.012 15.5 0.2 0.019 14.8 0.2 1.5 1 0 0 1 1 1 0 Rossmann-like domain 2-Hacid_dh_C PF02826.19 AAL62878.1 - 0.013 14.9 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 AAL62878.1 - 0.024 14.3 0.0 0.17 11.6 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 AAL62878.1 - 0.054 13.5 0.2 0.24 11.4 0.0 2.0 1 1 1 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Flavodoxin_1 PF00258.25 AAL62878.1 - 0.072 13.3 0.0 0.21 11.8 0.0 1.9 1 1 1 2 2 2 0 Flavodoxin F420_oxidored PF03807.17 AAL62878.1 - 0.13 12.9 0.8 0.47 11.1 0.2 2.3 2 1 1 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Flp1_like PF16982.5 AAL62879.1 - 0.0015 17.9 3.0 0.0037 16.6 2.1 1.8 1 1 1 2 2 2 1 Putative Flagellin, Flp1-like, domain VIT1 PF01988.19 AAL62879.1 - 0.016 15.1 1.7 0.017 15.0 1.7 1.0 1 0 0 1 1 1 0 VIT family DUF3852 PF12963.7 AAL62879.1 - 0.069 13.5 2.0 0.075 13.4 2.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3852) Ribosomal_S5_C PF03719.15 AAL62879.1 - 0.073 12.5 0.2 0.085 12.3 0.2 1.2 1 0 0 1 1 1 0 Ribosomal protein S5, C-terminal domain HEM4 PF02602.15 AAL62880.1 - 1.2e-17 64.1 1.0 1.6e-17 63.7 1.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD AIRS_C PF02769.22 AAL62880.1 - 0.054 13.6 0.1 0.073 13.2 0.1 1.4 1 0 0 1 1 1 0 AIR synthase related protein, C-terminal domain UDPG_MGDP_dh_C PF03720.15 AAL62880.1 - 0.11 12.9 0.1 0.36 11.3 0.1 2.0 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain LRV PF01816.17 AAL62880.1 - 2.3 8.8 4.3 23 5.7 0.4 3.3 3 0 0 3 3 3 0 Leucine rich repeat variant TP_methylase PF00590.20 AAL62881.1 - 9.5e-46 156.4 0.1 1.1e-45 156.2 0.1 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases AlaDh_PNT_C PF01262.21 AAL62881.1 - 0.065 12.5 0.0 0.17 11.1 0.0 1.7 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Aminotran_3 PF00202.21 AAL62882.1 - 2.3e-62 211.0 0.0 2.9e-62 210.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III DegT_DnrJ_EryC1 PF01041.17 AAL62882.1 - 0.011 15.1 0.0 0.024 14.0 0.0 1.5 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Radical_SAM PF04055.21 AAL62883.1 - 8.7e-17 62.0 0.0 1.8e-16 61.0 0.0 1.6 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 AAL62883.1 - 1.2e-06 28.8 0.0 3.7e-06 27.3 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S single cluster domain SPASM PF13186.6 AAL62883.1 - 5.8e-05 23.5 0.0 0.00021 21.7 0.0 2.0 1 1 1 2 2 2 1 Iron-sulfur cluster-binding domain Fer4_14 PF13394.6 AAL62883.1 - 0.0011 19.1 0.0 0.0021 18.2 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Dioxygenase_N PF04444.14 AAL62883.1 - 0.0069 16.2 0.0 0.019 14.8 0.0 1.7 1 0 0 1 1 1 1 Catechol dioxygenase N terminus zf-TFIIB PF13453.6 AAL62884.1 - 6.4e-16 57.4 1.6 9.3e-16 56.9 1.6 1.3 1 0 0 1 1 1 1 Transcription factor zinc-finger zinc_ribbon_2 PF13240.6 AAL62884.1 - 0.0037 16.9 0.0 0.0076 15.9 0.0 1.5 1 1 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.6 AAL62884.1 - 0.011 15.1 2.0 1.8 8.1 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Prok-RING_1 PF14446.6 AAL62884.1 - 0.096 12.6 0.8 0.16 12.0 0.8 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-tcix PF14952.6 AAL62884.1 - 0.4 10.3 2.7 15 5.3 0.3 2.2 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding zf-NADH-PPase PF09297.11 AAL62884.1 - 1.7 8.4 4.5 28 4.5 0.0 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Zn-ribbon_8 PF09723.10 AAL62884.1 - 1.9 8.7 5.7 4.1 7.6 3.0 2.4 2 1 0 2 2 2 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 AAL62884.1 - 3.6 7.6 5.7 34 4.5 3.7 2.7 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Mu-like_Com PF10122.9 AAL62884.1 - 4.7 6.7 5.0 2 8.0 0.6 2.3 2 1 1 3 3 3 0 Mu-like prophage protein Com CbiX PF01903.17 AAL62885.1 - 0.011 16.0 0.1 0.14 12.5 0.0 2.5 2 2 0 2 2 2 0 CbiX Zip PF02535.22 AAL62886.1 - 1.2e-05 24.8 11.5 0.00015 21.1 4.5 2.3 2 0 0 2 2 2 2 ZIP Zinc transporter DUF4149 PF13664.6 AAL62886.1 - 8.6 6.7 13.6 0.55 10.6 5.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) GlutR_N PF05201.15 AAL62887.1 - 5.3e-29 100.9 4.4 8.8e-29 100.2 0.2 2.5 3 0 0 3 3 3 1 Glutamyl-tRNAGlu reductase, N-terminal domain Shikimate_DH PF01488.20 AAL62887.1 - 3.1e-21 75.9 0.1 7.6e-21 74.6 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 AAL62887.1 - 9.7e-10 38.9 0.2 9.7e-10 38.9 0.2 2.3 3 0 0 3 3 2 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 AAL62887.1 - 7e-05 23.1 0.1 0.00018 21.8 0.1 1.7 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ThiF PF00899.21 AAL62887.1 - 9.3e-05 21.9 0.3 0.00019 20.9 0.3 1.5 1 0 0 1 1 1 1 ThiF family NAD_binding_2 PF03446.15 AAL62887.1 - 0.00012 22.2 0.1 0.00036 20.7 0.1 1.8 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 AAL62887.1 - 0.00055 19.3 0.1 0.0021 17.5 0.0 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 AAL62887.1 - 0.0012 18.9 0.0 0.0039 17.2 0.0 1.9 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.21 AAL62887.1 - 0.0016 17.8 0.1 0.0036 16.6 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 AAL62887.1 - 0.0057 16.5 0.3 0.0057 16.5 0.3 2.1 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2201 PF09967.9 AAL62887.1 - 0.01 16.0 0.1 1.8 8.7 0.0 2.7 2 0 0 2 2 2 0 VWA-like domain (DUF2201) NAD_binding_7 PF13241.6 AAL62887.1 - 0.012 16.1 0.1 0.028 14.9 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding GlutR_dimer PF00745.20 AAL62887.1 - 0.012 16.1 7.3 0.02 15.4 2.8 3.4 3 1 0 3 3 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain FAD_binding_3 PF01494.19 AAL62887.1 - 0.022 14.0 0.2 0.044 13.0 0.2 1.5 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 AAL62887.1 - 0.027 13.7 0.1 0.053 12.8 0.1 1.6 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.16 AAL62887.1 - 0.033 13.8 0.0 0.059 13.0 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.6 AAL62887.1 - 0.051 13.5 0.4 0.093 12.6 0.4 1.6 1 0 0 1 1 1 0 NAD(P)H-binding KR PF08659.10 AAL62887.1 - 0.057 13.3 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 KR domain IlvN PF07991.12 AAL62887.1 - 0.075 12.6 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain DAO PF01266.24 AAL62887.1 - 1.1 8.8 4.9 0.51 9.9 1.7 2.0 2 1 0 2 2 2 0 FAD dependent oxidoreductase PaRep2a PF07903.11 AAL62888.1 - 0.0085 15.9 0.0 0.0085 15.9 0.0 1.0 1 0 0 1 1 1 1 PaRep2a protein DUF1297 PF06973.12 AAL62889.1 - 1.4e-80 269.3 0.0 1.7e-80 269.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1297) DUF1246 PF06849.12 AAL62889.1 - 2.6e-47 159.8 0.0 3.9e-47 159.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1246) Fer4_15 PF13459.6 AAL62890.1 - 3.9e-16 59.6 0.1 4.3e-16 59.4 0.1 1.0 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_13 PF13370.6 AAL62890.1 - 5.6e-05 23.6 0.1 0.00014 22.3 0.1 1.6 1 1 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4 PF00037.27 AAL62890.1 - 0.011 15.6 4.1 0.12 12.3 1.1 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_2 PF12797.7 AAL62890.1 - 0.012 15.7 0.4 0.012 15.7 0.4 1.9 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.7 AAL62890.1 - 0.064 13.4 1.3 0.2 11.8 0.2 2.0 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_3 PF12798.7 AAL62890.1 - 5.3 8.2 7.4 21 6.4 3.6 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Aldo_ket_red PF00248.21 AAL62891.1 - 2.9e-39 135.0 0.0 2.5e-37 128.7 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family DUF1297 PF06973.12 AAL62892.1 - 3.1e-55 186.7 0.2 6.9e-55 185.5 0.2 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1297) DUF1246 PF06849.12 AAL62892.1 - 5.8e-40 136.1 0.0 9.2e-40 135.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1246) ATP-grasp_3 PF02655.14 AAL62892.1 - 0.00018 21.6 0.0 0.00038 20.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 AAL62892.1 - 0.00071 19.2 0.0 0.0018 17.9 0.0 1.6 1 1 0 1 1 1 1 RimK-like ATP-grasp domain CPSase_L_D2 PF02786.17 AAL62892.1 - 0.0035 16.9 0.0 0.0063 16.0 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 AAL62892.1 - 0.13 11.9 0.1 0.44 10.1 0.0 1.8 2 0 0 2 2 2 0 ATP-grasp domain DUF3182 PF11379.8 AAL62892.1 - 0.19 10.7 0.0 0.35 9.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3182) TFIIB PF00382.19 AAL62893.1 - 0.00031 20.7 0.3 0.0007 19.6 0.1 1.6 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Beta-APP PF03494.13 AAL62893.1 - 0.079 12.8 0.3 0.16 11.8 0.3 1.5 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Arch_fla_DE PF04659.13 AAL62893.1 - 0.089 12.7 0.3 0.98 9.3 0.1 2.3 2 0 0 2 2 2 0 Archaeal flagella protein HTH_45 PF14947.6 AAL62894.1 - 4.4e-11 42.6 0.0 5.5e-11 42.3 0.0 1.0 1 0 0 1 1 1 1 Winged helix-turn-helix HemN_C PF06969.16 AAL62894.1 - 0.032 14.3 0.0 0.057 13.5 0.0 1.4 1 0 0 1 1 1 0 HemN C-terminal domain HTH_5 PF01022.20 AAL62894.1 - 0.05 13.5 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family DUF488 PF04343.13 AAL62896.1 - 4.1e-27 95.2 0.0 6.9e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF488 ILVD_EDD PF00920.21 AAL62897.1 - 1.8e-199 663.7 0.0 2e-199 663.5 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family Radical_SAM PF04055.21 AAL62898.1 - 3.7e-23 82.7 0.0 6.1e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Complex1_49kDa PF00346.19 AAL62899.1 - 1.9e-29 102.6 0.0 2.3e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit DUF1845 PF08900.11 AAL62899.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1845) CitMHS PF03600.16 AAL62900.1 - 0.25 10.5 10.3 0.28 10.3 10.3 1.0 1 0 0 1 1 1 0 Citrate transporter Bacteriocin_IId PF09221.10 AAL62900.1 - 0.68 10.1 13.0 0.2 11.8 9.2 2.2 1 1 1 2 2 2 0 Bacteriocin class IId cyclical uberolysin-like AFOR_C PF01314.18 AAL62901.1 - 3e-118 395.1 0.1 3.9e-118 394.8 0.1 1.1 1 0 0 1 1 1 1 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 AFOR_N PF02730.15 AAL62901.1 - 2.8e-72 242.8 0.1 5.4e-72 241.8 0.1 1.5 1 0 0 1 1 1 1 Aldehyde ferredoxin oxidoreductase, N-terminal domain NAD_kinase PF01513.21 AAL62902.1 - 2.2e-18 66.5 0.2 4.9e-18 65.3 0.2 1.5 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 AAL62902.1 - 0.025 14.2 0.0 0.05 13.2 0.0 1.5 1 1 0 1 1 1 0 Diacylglycerol kinase catalytic domain NUC205 PF08168.11 AAL62902.1 - 0.15 11.6 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 NUC205 domain PIN_6 PF17146.4 AAL62903.1 - 1.1e-07 32.2 0.0 2.6e-07 31.0 0.0 1.5 1 1 0 1 1 1 1 PIN domain of ribonuclease PIN PF01850.21 AAL62903.1 - 5.9e-07 30.0 0.1 1.3e-06 29.0 0.1 1.7 1 1 0 1 1 1 1 PIN domain PIN_5 PF08745.11 AAL62903.1 - 0.00067 19.1 0.4 0.0013 18.2 0.4 1.5 1 1 0 1 1 1 1 PINc domain ribonuclease DUF4411 PF14367.6 AAL62903.1 - 0.0022 17.9 0.0 0.12 12.3 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4411) TPR_12 PF13424.6 AAL62904.1 - 0.038 14.3 0.3 0.33 11.3 0.1 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF371 PF04027.13 AAL62905.1 - 1.5e-37 128.5 0.0 1.8e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF371) tRNA-synt_1b PF00579.25 AAL62906.1 - 4.3e-42 144.4 0.0 6.7e-42 143.8 0.0 1.3 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) HD PF01966.22 AAL62907.1 - 2.5e-11 43.9 0.3 6.8e-11 42.5 0.3 1.9 1 0 0 1 1 1 1 HD domain HDOD PF08668.12 AAL62907.1 - 0.17 11.3 0.1 0.29 10.6 0.1 1.3 1 0 0 1 1 1 0 HDOD domain Pyr_redox_2 PF07992.14 AAL62908.1 - 0.00047 19.5 0.0 0.001 18.4 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 AAL62908.1 - 0.0012 18.0 0.2 0.49 9.4 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein DAO PF01266.24 AAL62908.1 - 0.0082 15.8 0.2 0.044 13.4 0.2 1.9 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AAL62908.1 - 0.033 14.4 0.5 0.11 12.7 0.1 2.1 2 1 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 AAL62908.1 - 0.045 13.0 1.8 4.8 6.3 0.2 2.2 2 0 0 2 2 2 0 FAD binding domain SapB_1 PF05184.15 AAL62909.1 - 0.1 12.6 0.2 9.2 6.4 0.0 2.4 2 0 0 2 2 2 0 Saposin-like type B, region 1 Methyltransf_25 PF13649.6 AAL62910.1 - 3e-06 27.9 0.0 5.5e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AAL62910.1 - 1.5e-05 24.6 0.0 2e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 AAL62910.1 - 2.5e-05 24.0 0.0 4.3e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 AAL62910.1 - 3.1e-05 24.5 0.0 0.0001 22.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Spermine_synth PF01564.17 AAL62910.1 - 0.00018 21.0 0.0 0.00053 19.5 0.0 1.7 1 1 0 1 1 1 1 Spermine/spermidine synthase domain UPF0020 PF01170.18 AAL62910.1 - 0.0085 15.8 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Peptidase_M24 PF00557.24 AAL62911.1 - 6.4e-58 195.9 0.3 8.8e-58 195.4 0.3 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 AAL62911.1 - 0.00025 21.7 0.0 0.00069 20.3 0.0 1.7 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Transketolase_C PF02780.20 AAL62911.1 - 0.22 11.4 2.9 10 6.0 0.1 2.7 3 0 0 3 3 3 0 Transketolase, C-terminal domain ASCH PF04266.14 AAL62912.1 - 1.5e-11 44.9 0.2 1.8e-11 44.5 0.2 1.1 1 0 0 1 1 1 1 ASCH domain DUF3051 PF11252.8 AAL62912.1 - 0.15 11.8 0.1 0.18 11.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3051) PLU-1 PF08429.11 AAL62913.1 - 0.069 12.3 0.1 0.088 12.0 0.1 1.1 1 0 0 1 1 1 0 PLU-1-like protein Peptidase_C26 PF07722.13 AAL62913.1 - 0.072 12.8 0.0 0.099 12.4 0.0 1.1 1 0 0 1 1 1 0 Peptidase C26 HTH_IclR PF09339.10 AAL62914.1 - 1.4e-09 37.6 0.6 2.5e-09 36.8 0.0 1.6 2 0 0 2 2 2 1 IclR helix-turn-helix domain MarR_2 PF12802.7 AAL62914.1 - 1.4e-08 34.5 0.3 3.2e-08 33.3 0.0 1.7 2 0 0 2 2 2 1 MarR family Fe_dep_repress PF01325.19 AAL62914.1 - 2.6e-08 33.9 0.1 4.2e-08 33.3 0.1 1.3 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_24 PF13412.6 AAL62914.1 - 6.9e-08 31.9 1.1 1.3e-07 31.1 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding TrmB PF01978.19 AAL62914.1 - 8.9e-08 31.9 0.1 1.4e-07 31.3 0.1 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.7 AAL62914.1 - 1e-05 25.5 0.0 2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 AAL62914.1 - 2.4e-05 24.1 0.1 4.3e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family GntR PF00392.21 AAL62914.1 - 6.2e-05 22.6 0.1 0.00014 21.5 0.1 1.8 1 1 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_27 PF13463.6 AAL62914.1 - 0.00018 21.9 0.0 0.00034 21.0 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_23 PF13384.6 AAL62914.1 - 0.00019 21.1 0.0 0.00046 19.9 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_11 PF08279.12 AAL62914.1 - 0.00026 20.9 0.1 0.00047 20.0 0.1 1.4 1 0 0 1 1 1 1 HTH domain MarR PF01047.22 AAL62914.1 - 0.00034 20.5 0.1 0.0008 19.3 0.0 1.6 2 0 0 2 2 2 1 MarR family Rrf2 PF02082.20 AAL62914.1 - 0.0011 19.3 0.1 0.0019 18.5 0.1 1.3 1 0 0 1 1 1 1 Transcriptional regulator HTH_AsnC-type PF13404.6 AAL62914.1 - 0.0018 18.0 0.5 0.008 16.0 0.0 2.2 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_Crp_2 PF13545.6 AAL62914.1 - 0.0026 17.7 0.1 0.0072 16.3 0.0 1.7 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_29 PF13551.6 AAL62914.1 - 0.0031 17.5 0.1 0.0063 16.5 0.0 1.6 2 0 0 2 2 1 1 Winged helix-turn helix HTH_41 PF14502.6 AAL62914.1 - 0.0033 17.1 0.0 0.0082 15.8 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain LexA_DNA_bind PF01726.16 AAL62914.1 - 0.0047 16.7 0.1 0.024 14.4 0.1 2.1 1 1 1 2 2 2 1 LexA DNA binding domain Penicillinase_R PF03965.16 AAL62914.1 - 0.005 17.2 0.0 0.0086 16.4 0.0 1.4 1 0 0 1 1 1 1 Penicillinase repressor TFIIE_alpha PF02002.17 AAL62914.1 - 0.005 16.7 0.0 0.0071 16.2 0.0 1.2 1 0 0 1 1 1 1 TFIIE alpha subunit HTH_46 PF15977.5 AAL62914.1 - 0.0053 16.8 0.1 0.0084 16.1 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA binding RPA_C PF08784.11 AAL62914.1 - 0.015 15.9 0.0 0.02 15.5 0.0 1.2 1 0 0 1 1 1 0 Replication protein A C terminal HTH_CodY PF08222.11 AAL62914.1 - 0.048 13.2 0.0 0.076 12.6 0.0 1.3 1 0 0 1 1 1 0 CodY helix-turn-helix domain DUF2250 PF10007.9 AAL62914.1 - 0.055 13.6 0.0 0.076 13.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) PaaX PF07848.12 AAL62914.1 - 0.062 13.5 0.2 0.12 12.7 0.0 1.6 2 0 0 2 2 1 0 PaaX-like protein HTH_10 PF04967.12 AAL62914.1 - 0.063 13.1 0.5 0.2 11.5 0.0 2.0 2 1 0 2 2 2 0 HTH DNA binding domain HTH_28 PF13518.6 AAL62914.1 - 0.072 13.2 0.1 0.17 12.1 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_34 PF13601.6 AAL62914.1 - 0.076 13.2 0.0 0.14 12.3 0.0 1.5 2 0 0 2 2 1 0 Winged helix DNA-binding domain HTH_36 PF13730.6 AAL62914.1 - 0.096 12.7 0.0 0.23 11.4 0.0 1.6 1 1 0 1 1 1 0 Helix-turn-helix domain CM_2 PF01817.21 AAL62914.1 - 0.1 12.9 0.0 0.18 12.2 0.0 1.6 1 1 0 1 1 1 0 Chorismate mutase type II HTH_micro PF17007.5 AAL62914.1 - 0.22 10.3 0.0 0.29 9.9 0.0 1.1 1 0 0 1 1 1 0 HTH-like DUF5645 PF18713.1 AAL62915.1 - 0.041 14.2 0.0 0.058 13.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5645) SLAC1 PF03595.17 AAL62916.1 - 0.047 12.9 17.0 0.058 12.6 17.0 1.1 1 0 0 1 1 1 0 Voltage-dependent anion channel RimK PF08443.11 AAL62918.1 - 1.2e-34 119.6 0.0 1.6e-34 119.2 0.0 1.1 1 0 0 1 1 1 1 RimK-like ATP-grasp domain GSH-S_ATP PF02955.16 AAL62918.1 - 2.1e-14 53.3 0.0 3.1e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATP-grasp_3 PF02655.14 AAL62918.1 - 1.4e-09 38.2 0.0 2.2e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 AAL62918.1 - 3.1e-09 36.5 0.0 0.0044 16.3 0.0 3.1 1 1 2 3 3 3 3 Sugar-transfer associated ATP-grasp TTL PF03133.15 AAL62918.1 - 0.0019 17.4 0.0 0.0055 15.9 0.0 1.6 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 AAL62918.1 - 0.0042 16.4 0.0 0.23 10.7 0.0 2.4 2 0 0 2 2 2 1 YheC/D like ATP-grasp Rimk_N PF18030.1 AAL62918.1 - 0.02 15.3 0.0 0.032 14.6 0.0 1.4 1 0 0 1 1 1 0 RimK PreATP-grasp domain ATP-grasp PF02222.22 AAL62918.1 - 0.026 14.1 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain THOC7 PF05615.13 AAL62920.1 - 0.0063 16.8 4.8 0.009 16.3 4.8 1.4 1 0 0 1 1 1 1 Tho complex subunit 7 HrpB7 PF09486.10 AAL62920.1 - 0.011 16.1 6.1 0.33 11.3 5.0 2.1 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) V-SNARE_C PF12352.8 AAL62920.1 - 0.012 15.9 0.9 0.75 10.1 0.2 2.4 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus AAA_13 PF13166.6 AAL62920.1 - 0.019 13.6 4.0 0.022 13.4 4.0 1.1 1 0 0 1 1 1 0 AAA domain Leu_zip PF15294.6 AAL62920.1 - 0.026 14.0 8.4 0.05 13.1 8.4 1.4 1 1 0 1 1 1 0 Leucine zipper DUF4200 PF13863.6 AAL62920.1 - 0.063 13.7 8.5 1.1 9.6 4.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Baculo_PEP_C PF04513.12 AAL62920.1 - 0.075 13.1 0.9 0.45 10.6 0.6 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Atg14 PF10186.9 AAL62920.1 - 0.13 11.3 7.5 0.2 10.7 7.5 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 AAL62920.1 - 0.14 12.2 4.0 0.21 11.6 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Snapin_Pallidin PF14712.6 AAL62920.1 - 0.24 11.9 7.0 0.27 11.7 3.8 2.3 1 1 1 2 2 2 0 Snapin/Pallidin BLOC1_2 PF10046.9 AAL62920.1 - 0.24 11.7 7.1 5.3 7.4 2.9 2.5 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 AAL62920.1 - 0.3 9.9 7.6 0.42 9.5 7.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF724 PF05266.14 AAL62920.1 - 0.31 10.8 4.4 0.49 10.2 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DLP_helical PF18709.1 AAL62920.1 - 0.37 9.9 6.4 2.7 7.1 6.4 1.9 1 1 1 2 2 2 0 Dynamin-like helical domain COG5 PF10392.9 AAL62920.1 - 0.42 10.8 5.4 1.2 9.3 0.2 2.6 1 1 1 2 2 2 0 Golgi transport complex subunit 5 DUF745 PF05335.13 AAL62920.1 - 0.79 9.4 3.1 1.1 9.0 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DUF16 PF01519.16 AAL62920.1 - 0.9 10.1 5.9 6 7.4 5.9 2.3 1 1 0 1 1 1 0 Protein of unknown function DUF16 Prefoldin PF02996.17 AAL62920.1 - 1.3 8.9 9.0 4.5 7.2 0.2 2.9 2 1 1 3 3 3 0 Prefoldin subunit OmpH PF03938.14 AAL62920.1 - 1.8 8.9 9.8 2.7 8.3 0.6 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF3782 PF12644.7 AAL62920.1 - 3.6 7.8 5.7 16 5.7 0.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3782) UDG PF03167.19 AAL62921.1 - 2e-40 138.3 0.0 2.5e-40 138.0 0.0 1.0 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily SHOCT PF09851.9 AAL62922.1 - 9.6 6.1 5.8 6.4 6.6 3.4 2.0 2 0 0 2 2 2 0 Short C-terminal domain DUF2070 PF09843.9 AAL62923.1 - 4e-114 381.9 3.0 4.9e-114 381.7 3.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) Rad51 PF08423.11 AAL62924.1 - 1.5e-97 325.9 0.0 1.9e-97 325.5 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 AAL62924.1 - 4.3e-15 55.9 0.1 6.4e-15 55.3 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 AAL62924.1 - 5.2e-12 45.6 0.0 1.1e-11 44.5 0.0 1.7 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.6 AAL62924.1 - 5.9e-10 39.6 1.1 5.7e-09 36.5 0.4 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain AAA_25 PF13481.6 AAL62924.1 - 1.7e-08 34.3 0.1 3e-08 33.5 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AAL62924.1 - 0.0004 20.7 0.1 0.00085 19.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AAL62924.1 - 0.0014 19.2 0.0 0.0031 18.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain PAXNEB PF05625.11 AAL62924.1 - 0.0092 15.2 0.1 0.25 10.4 0.0 2.2 2 0 0 2 2 2 1 PAXNEB protein BAF PF02961.14 AAL62924.1 - 0.015 15.7 0.0 0.035 14.5 0.0 1.5 1 0 0 1 1 1 0 Barrier to autointegration factor HhH-GPD PF00730.25 AAL62924.1 - 0.025 15.0 0.0 0.075 13.5 0.0 1.9 1 1 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein DUF1318 PF07027.12 AAL62924.1 - 0.031 14.7 0.2 11 6.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1318) AAA_24 PF13479.6 AAL62924.1 - 0.057 13.1 0.0 0.087 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 AAL62924.1 - 0.075 12.7 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain IMS_HHH PF11798.8 AAL62924.1 - 0.078 13.3 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 IMS family HHH motif ABC_tran PF00005.27 AAL62924.1 - 0.1 13.1 0.1 0.25 11.8 0.0 1.8 2 1 0 2 2 2 0 ABC transporter YafQ_toxin PF15738.5 AAL62925.1 - 0.16 12.3 0.0 0.33 11.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial toxin of type II toxin-antitoxin system, YafQ Radical_SAM PF04055.21 AAL62926.1 - 1.9e-15 57.7 0.1 2.3e-14 54.1 0.0 2.5 3 0 0 3 3 3 1 Radical SAM superfamily TERT_thumb PF17984.1 AAL62927.1 - 0.24 11.3 0.0 0.33 10.8 0.0 1.2 1 0 0 1 1 1 0 Telomerase reverse transcriptase thumb DNA binding domain zf-Di19 PF05605.12 AAL62928.1 - 7.6e-09 35.7 9.3 4e-06 27.0 5.8 2.6 1 1 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 AAL62928.1 - 1.6e-07 31.6 14.7 0.0011 19.6 0.0 3.6 4 0 0 4 4 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 AAL62928.1 - 3.9e-07 30.2 13.3 5.3e-05 23.4 0.0 3.7 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf_UBZ PF18439.1 AAL62928.1 - 0.00044 19.8 6.1 0.19 11.4 0.2 3.5 3 0 0 3 3 3 1 Ubiquitin-Binding Zinc Finger zf-C2H2_jaz PF12171.8 AAL62928.1 - 0.00073 19.8 4.6 0.16 12.3 0.0 3.7 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 AAL62928.1 - 0.00088 19.1 5.5 0.3 11.0 0.0 3.6 3 0 0 3 3 3 1 zinc-finger of a C2HC-type zf-C2H2_9 PF16293.5 AAL62928.1 - 0.0034 17.2 7.1 0.98 9.3 0.3 3.2 1 1 2 3 3 3 1 C2H2 type zinc-finger (1 copy) zf-C3HC4_3 PF13920.6 AAL62928.1 - 0.0035 17.2 7.7 0.57 10.1 1.6 3.1 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Zn-ribbon_8 PF09723.10 AAL62928.1 - 0.0042 17.2 3.3 0.19 11.9 0.3 3.0 2 1 1 3 3 3 1 Zinc ribbon domain zf-C2H2_6 PF13912.6 AAL62928.1 - 0.015 15.3 9.6 0.04 13.9 0.0 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger YacG PF03884.14 AAL62928.1 - 0.016 14.9 5.0 1.5 8.7 0.2 2.7 3 0 0 3 3 2 0 DNA gyrase inhibitor YacG zf-RING_5 PF14634.6 AAL62928.1 - 0.033 14.2 8.1 8.5 6.4 3.1 3.1 3 0 0 3 3 3 0 zinc-RING finger domain Sgf11 PF08209.11 AAL62928.1 - 0.033 13.8 5.1 3.8 7.2 0.1 3.2 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) Cript PF10235.9 AAL62928.1 - 0.044 14.4 9.3 0.14 12.7 1.8 2.3 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT DUF1644 PF07800.12 AAL62928.1 - 0.047 13.8 5.5 0.13 12.3 5.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) zinc-ribbons_6 PF07191.12 AAL62928.1 - 0.047 13.7 8.2 3.7 7.6 8.4 2.6 1 1 0 1 1 1 0 zinc-ribbons DUF2318 PF10080.9 AAL62928.1 - 0.053 13.6 9.7 0.53 10.4 1.6 2.9 1 1 2 3 3 3 0 Predicted membrane protein (DUF2318) Prok-RING_4 PF14447.6 AAL62928.1 - 0.054 13.4 8.3 0.69 9.8 0.4 3.0 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 DZR PF12773.7 AAL62928.1 - 0.063 13.3 9.3 1.2 9.2 0.9 2.6 1 1 0 2 2 2 0 Double zinc ribbon RNF220 PF15926.5 AAL62928.1 - 0.068 12.8 3.9 0.065 12.9 2.2 1.9 1 1 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 zf-BED PF02892.15 AAL62928.1 - 0.15 12.1 14.2 3.2 7.9 2.0 3.4 1 1 2 3 3 3 0 BED zinc finger PRP21_like_P PF12230.8 AAL62928.1 - 0.16 11.8 1.9 1.3 8.8 0.1 2.2 1 1 1 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein zf-C2H2_2 PF12756.7 AAL62928.1 - 0.19 12.1 11.7 1.6 9.1 1.4 3.4 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) UCH_1 PF13423.6 AAL62928.1 - 0.24 11.0 3.1 0.27 10.8 3.1 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Cys_rich_KTR PF14205.6 AAL62928.1 - 0.29 10.9 4.7 0.11 12.3 0.7 2.4 2 1 0 2 2 2 0 Cysteine-rich KTR DUF629 PF04780.12 AAL62928.1 - 0.3 9.6 5.9 1.9 6.9 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF629) Endonuclease_7 PF02945.15 AAL62928.1 - 0.31 11.0 11.0 0.48 10.4 6.0 2.4 1 1 1 2 2 2 0 Recombination endonuclease VII zinc_ribbon_9 PF14369.6 AAL62928.1 - 0.67 10.3 9.7 5.3 7.4 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon DUF2256 PF10013.9 AAL62928.1 - 0.69 10.1 10.3 2 8.6 0.3 3.5 4 0 0 4 4 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-met PF12874.7 AAL62928.1 - 0.87 10.1 0.0 0.87 10.1 0.0 4.5 5 1 0 5 5 4 0 Zinc-finger of C2H2 type zf-LSD1 PF06943.12 AAL62928.1 - 1.1 9.2 0.1 1.1 9.2 0.1 2.9 3 0 0 3 3 2 0 LSD1 zinc finger zf-piccolo PF05715.13 AAL62928.1 - 1.1 9.5 9.7 0.28 11.4 0.4 2.6 2 1 0 2 2 2 0 Piccolo Zn-finger zf-ribbon_3 PF13248.6 AAL62928.1 - 1.2 8.6 9.7 0.75 9.3 0.2 3.6 4 0 0 4 4 4 0 zinc-ribbon domain DUF2039 PF10217.9 AAL62928.1 - 1.7 9.0 12.9 4.7 7.6 12.9 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) HNH PF01844.23 AAL62928.1 - 2.4 8.4 16.2 1.8 8.8 2.8 3.5 3 1 1 4 4 3 0 HNH endonuclease DUF2197 PF09963.9 AAL62928.1 - 3.9 7.8 10.1 4.2 7.7 0.8 2.6 3 0 0 3 3 2 0 Uncharacterized protein conserved in bacteria (DUF2197) Zf_RING PF16744.5 AAL62928.1 - 4.6 7.4 10.6 13 6.0 0.2 3.1 2 1 1 3 3 3 0 KIAA1045 RING finger DUF2225 PF09986.9 AAL62928.1 - 4.7 6.9 8.4 1.9 8.2 2.0 2.4 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C3HC4 PF00097.25 AAL62928.1 - 8.4 6.4 11.2 9.2 6.2 2.2 2.9 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) BIR PF00653.21 AAL62928.1 - 9.2 7.0 12.4 16 6.3 2.5 2.9 1 1 2 3 3 3 0 Inhibitor of Apoptosis domain CarS-like PF01864.17 AAL62929.1 - 7.1e-40 136.8 2.9 2.5e-39 135.0 2.9 1.7 1 1 0 1 1 1 1 CDP-archaeol synthase CTP_transf_1 PF01148.20 AAL62929.1 - 0.003 17.4 0.4 0.003 17.4 0.4 1.7 2 0 0 2 2 2 1 Cytidylyltransferase family ATP-synt_F PF01990.17 AAL62930.1 - 1.8e-15 57.0 0.2 2.2e-15 56.7 0.2 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit vATP-synt_E PF01991.18 AAL62931.1 - 7.2e-12 45.1 2.6 3.3e-11 43.0 2.6 1.9 1 1 0 1 1 1 1 ATP synthase (E/31 kDa) subunit AAA_21 PF13304.6 AAL62931.1 - 0.019 14.8 0.2 0.024 14.4 0.2 1.1 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system ATP-synt_ab PF00006.25 AAL62932.1 - 1.2e-79 266.9 0.0 1.6e-79 266.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 AAL62932.1 - 1.2e-37 128.5 0.0 1.9e-37 127.8 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 AAL62932.1 - 4e-12 46.5 0.2 9.4e-12 45.3 0.2 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_22 PF13401.6 AAL62932.1 - 0.018 15.3 0.0 0.037 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Peptidase_M23 PF01551.22 AAL62932.1 - 0.18 12.0 0.0 14 5.9 0.0 2.7 2 0 0 2 2 2 0 Peptidase family M23 RNA_pol_Rpb5_C PF01191.19 AAL62933.1 - 2.8e-24 84.8 0.0 3.2e-24 84.6 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb2_6 PF00562.28 AAL62934.1 - 2.9e-134 448.0 0.0 3.7e-134 447.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 AAL62934.1 - 2.2e-47 161.2 0.0 3.3e-47 160.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 AAL62934.1 - 9.1e-30 103.7 0.0 1.6e-29 102.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 AAL62934.1 - 2.3e-28 98.4 0.0 6.3e-28 97.0 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 AAL62934.1 - 7.4e-27 93.3 0.0 1.8e-26 92.1 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 AAL62934.1 - 5.4e-21 74.7 1.0 1.3e-20 73.5 1.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 AAL62934.1 - 3.5e-09 37.1 1.8 3.1e-08 34.0 1.8 2.4 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_45 PF10385.9 AAL62934.1 - 0.065 13.5 0.0 0.5 10.7 0.0 2.4 2 0 0 2 2 2 0 RNA polymerase beta subunit external 1 domain RNA_pol_Rpb1_1 PF04997.12 AAL62935.1 - 1.2e-97 327.1 0.0 1.6e-97 326.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 AAL62935.1 - 2.9e-73 245.5 0.0 4.7e-73 244.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 AAL62935.1 - 1.5e-33 116.0 0.0 3.7e-33 114.7 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 AAL62935.1 - 1.3e-26 92.6 0.0 2.7e-26 91.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_5 PF04998.17 AAL62935.1 - 9e-26 90.9 0.2 1.7e-25 90.0 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 zf-RING_7 PF02591.15 AAL62935.1 - 0.015 15.4 8.9 0.13 12.5 0.3 4.0 4 0 0 4 4 4 0 C4-type zinc ribbon domain CpXC PF14353.6 AAL62935.1 - 0.02 14.9 4.2 0.26 11.3 0.0 3.5 3 1 0 3 3 3 0 CpXC protein IBR PF01485.21 AAL62935.1 - 0.1 12.9 0.8 0.26 11.5 0.1 2.0 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-ribbon_3 PF13248.6 AAL62935.1 - 0.16 11.4 8.1 2.1 7.9 0.2 3.6 4 0 0 4 4 4 0 zinc-ribbon domain DZR PF12773.7 AAL62935.1 - 0.19 11.8 3.4 2.7 8.1 0.2 2.9 3 0 0 3 3 3 0 Double zinc ribbon zf-ISL3 PF14690.6 AAL62935.1 - 0.25 12.0 10.2 5.1 7.9 0.4 3.9 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zinc_ribbon_4 PF13717.6 AAL62935.1 - 0.46 10.4 4.3 13 5.8 0.2 3.5 3 0 0 3 3 3 0 zinc-ribbon domain Nudix_N_2 PF14803.6 AAL62935.1 - 0.5 10.3 8.2 8.3 6.4 0.1 3.5 3 0 0 3 3 3 0 Nudix N-terminal Zn-ribbon_8 PF09723.10 AAL62935.1 - 0.9 9.7 7.0 15 5.8 0.1 3.4 2 1 0 2 2 2 0 Zinc ribbon domain OrfB_Zn_ribbon PF07282.11 AAL62935.1 - 1.9 8.5 4.6 18 5.3 0.3 3.3 3 0 0 3 3 3 0 Putative transposase DNA-binding domain Auto_anti-p27 PF06677.12 AAL62935.1 - 2.3 8.5 6.2 0.85 9.8 0.0 2.9 3 0 0 3 3 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Zn_Tnp_IS1595 PF12760.7 AAL62935.1 - 3.7 7.6 10.1 1.7 8.7 0.2 3.5 4 0 0 4 4 3 0 Transposase zinc-ribbon domain Ribosomal_L44 PF00935.19 AAL62935.1 - 4.1 7.9 6.2 3.8 8.1 1.0 3.0 3 0 0 3 3 3 0 Ribosomal protein L44 zf-IS66 PF13005.7 AAL62935.1 - 6.2 7.3 7.6 8.4 6.9 0.0 3.8 4 0 0 4 4 3 0 zinc-finger binding domain of transposase IS66 RNA_pol_Rpb1_5 PF04998.17 AAL62936.1 - 2.6e-51 174.6 0.0 3.7e-51 174.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 HMA PF00403.26 AAL62936.1 - 0.0075 16.7 6.2 0.077 13.5 1.6 3.7 1 1 2 3 3 3 1 Heavy-metal-associated domain DUF211 PF02680.14 AAL62936.1 - 0.081 13.1 1.8 3 8.1 0.2 2.9 2 1 0 2 2 2 0 Uncharacterized ArCR, COG1888 PCI PF01399.27 AAL62936.1 - 0.14 12.7 0.2 0.53 10.8 0.0 2.0 2 0 0 2 2 2 0 PCI domain Ribosomal_L7Ae PF01248.26 AAL62937.1 - 5.3e-16 58.1 0.0 6.4e-16 57.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family KH_2 PF07650.17 AAL62938.1 - 1.3e-19 69.8 4.7 9.1e-15 54.3 0.7 2.1 1 1 1 2 2 2 2 KH domain KH_5 PF13184.6 AAL62938.1 - 1.9e-10 40.7 5.9 3.3e-10 39.9 1.5 2.2 2 0 0 2 2 2 1 NusA-like KH domain KH_4 PF13083.6 AAL62938.1 - 2.2e-05 24.2 0.5 0.0065 16.3 0.0 2.2 2 0 0 2 2 2 2 KH domain KH_1 PF00013.29 AAL62938.1 - 0.0024 17.6 2.9 0.18 11.7 0.3 2.9 2 1 1 3 3 3 2 KH domain Ribosom_S12_S23 PF00164.25 AAL62939.1 - 3.2e-44 149.2 0.2 4e-44 148.9 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 RNA_pol_A_bac PF01000.26 AAL62940.1 - 2.1e-26 92.5 0.0 3.9e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 AAL62940.1 - 1.7e-14 53.0 0.0 2.3e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Ribosomal_L18 PF17135.4 AAL62941.1 - 1.4e-10 40.9 0.2 1.8e-10 40.5 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 AAL62941.1 - 6.9e-08 33.2 1.7 1.1e-07 32.6 1.7 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_L13 PF00572.18 AAL62942.1 - 4e-12 46.5 0.6 2.1e-10 40.9 0.6 2.3 1 1 0 1 1 1 1 Ribosomal protein L13 Ribosomal_S9 PF00380.19 AAL62943.1 - 3.8e-31 108.1 0.1 4.6e-31 107.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S9/S16 RNA_pol_N PF01194.17 AAL62944.1 - 5.9e-27 93.7 0.3 6.6e-27 93.6 0.3 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 AAL62944.1 - 0.0079 16.4 0.2 0.017 15.4 0.2 1.5 1 1 0 1 1 1 1 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) LSM PF01423.22 AAL62945.1 - 2.5e-18 65.5 0.1 2.9e-18 65.3 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 AAL62945.1 - 0.017 15.3 0.0 0.021 15.0 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain AdoMet_Synthase PF01941.19 AAL62946.1 - 3.8e-172 572.5 4.1 4.2e-172 572.4 4.1 1.0 1 0 0 1 1 1 1 S-adenosylmethionine synthetase (AdoMet synthetase) TBCA PF02970.16 AAL62946.1 - 0.064 13.6 0.7 0.13 12.6 0.1 1.9 2 0 0 2 2 2 0 Tubulin binding cofactor A S-AdoMet_synt_N PF00438.20 AAL62946.1 - 1.4 9.6 3.8 6 7.6 0.0 3.1 3 1 1 4 4 4 0 S-adenosylmethionine synthetase, N-terminal domain DUF460 PF04312.13 AAL62947.1 - 2.8e-41 140.5 0.0 6e-41 139.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF460) GAS PF13851.6 AAL62947.1 - 9.6e-05 21.8 4.5 9.6e-05 21.8 4.5 2.9 3 0 0 3 3 3 1 Growth-arrest specific micro-tubule binding bZIP_1 PF00170.21 AAL62947.1 - 0.00022 21.2 1.2 0.00022 21.2 1.2 2.8 2 0 0 2 2 2 1 bZIP transcription factor ADIP PF11559.8 AAL62947.1 - 0.0035 17.4 5.4 0.0091 16.1 5.4 1.7 1 1 0 1 1 1 1 Afadin- and alpha -actinin-Binding Angiomotin_C PF12240.8 AAL62947.1 - 0.0097 15.5 3.6 0.064 12.8 1.3 2.6 2 0 0 2 2 2 1 Angiomotin C terminal RNase_E_G PF10150.9 AAL62947.1 - 0.012 15.1 2.0 0.025 14.0 2.0 1.7 1 0 0 1 1 1 0 Ribonuclease E/G family Cnn_1N PF07989.11 AAL62947.1 - 0.034 14.3 0.6 0.034 14.3 0.6 2.5 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 DUF3489 PF11994.8 AAL62947.1 - 0.045 13.8 0.0 4.1 7.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3489) bZIP_2 PF07716.15 AAL62947.1 - 0.29 11.2 9.2 0.051 13.7 1.4 2.9 2 0 0 2 2 2 0 Basic region leucine zipper FlaC_arch PF05377.11 AAL62947.1 - 0.4 11.1 4.8 20 5.7 0.4 3.3 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) Golgin_A5 PF09787.9 AAL62947.1 - 0.41 10.1 8.8 0.64 9.4 8.2 1.6 1 1 0 1 1 1 0 Golgin subfamily A member 5 CENP-F_leu_zip PF10473.9 AAL62947.1 - 1.3 9.0 12.2 0.22 11.6 6.9 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 THOC7 PF05615.13 AAL62947.1 - 2.6 8.3 11.1 9.6 6.5 4.0 3.4 3 1 1 4 4 4 0 Tho complex subunit 7 Cep57_CLD_2 PF14197.6 AAL62947.1 - 3.7 7.7 9.8 25 5.1 1.6 3.4 2 1 0 3 3 3 0 Centrosome localisation domain of PPC89 APG6_N PF17675.1 AAL62947.1 - 4.1 7.9 13.5 16 6.1 12.2 2.6 1 1 1 2 2 2 0 Apg6 coiled-coil region RIO1 PF01163.22 AAL62948.1 - 2.3e-35 121.9 0.0 3.4e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 AAL62948.1 - 6.1e-27 93.7 0.3 1.5e-26 92.4 0.3 1.7 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 AAL62948.1 - 1e-06 28.9 2.1 0.0011 19.0 0.0 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase PF00069.25 AAL62948.1 - 0.0049 16.3 0.0 0.0099 15.3 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain ABC1 PF03109.16 AAL62948.1 - 0.13 12.5 0.1 0.32 11.2 0.0 1.7 2 0 0 2 2 2 0 ABC1 family UPF0179 PF03684.13 AAL62949.1 - 9.5e-32 109.8 2.9 1.1e-31 109.6 2.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0179) DUF357 PF04010.13 AAL62950.1 - 1e-17 64.0 2.3 1.8e-17 63.1 2.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF357) CTP_transf_like PF01467.26 AAL62950.1 - 2.3e-12 47.3 0.0 3.7e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like Mur_ligase PF01225.25 AAL62950.1 - 0.048 14.0 0.0 0.29 11.5 0.0 2.2 2 0 0 2 2 2 0 Mur ligase family, catalytic domain Endonuclease_5 PF04493.14 AAL62951.1 - 1.9e-47 161.5 0.2 2.9e-47 160.9 0.2 1.2 1 0 0 1 1 1 1 Endonuclease V Usp PF00582.26 AAL62952.1 - 2.6e-31 109.0 6.7 7.1e-31 107.6 6.7 1.6 1 1 0 1 1 1 1 Universal stress protein family PGM_PMM_I PF02878.16 AAL62952.1 - 0.0018 18.0 0.3 0.43 10.3 0.1 2.1 1 1 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I ETF PF01012.21 AAL62952.1 - 0.007 16.3 3.8 0.009 15.9 3.2 1.5 1 1 0 1 1 1 1 Electron transfer flavoprotein domain Pilus_CpaD PF09476.10 AAL62952.1 - 0.011 15.5 0.6 0.012 15.4 0.6 1.2 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) PmbA_TldD PF01523.16 AAL62952.1 - 0.016 15.0 0.7 0.018 14.9 0.7 1.0 1 0 0 1 1 1 0 Putative modulator of DNA gyrase HGTP_anticodon PF03129.20 AAL62952.1 - 0.027 14.6 0.1 0.055 13.6 0.0 1.6 2 0 0 2 2 2 0 Anticodon binding domain DUF1471 PF07338.13 AAL62952.1 - 0.046 13.7 0.5 0.1 12.6 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1471) DAGK_cat PF00781.24 AAL62952.1 - 0.055 13.1 0.3 0.17 11.5 0.1 1.8 1 1 1 2 2 2 0 Diacylglycerol kinase catalytic domain VWA PF00092.28 AAL62952.1 - 0.078 13.2 0.2 0.27 11.5 0.2 1.7 1 1 0 1 1 1 0 von Willebrand factor type A domain AIRS PF00586.24 AAL62952.1 - 0.1 13.3 0.3 8.8 7.1 0.1 2.4 1 1 1 2 2 2 0 AIR synthase related protein, N-terminal domain AP_endonuc_2 PF01261.24 AAL62952.1 - 0.1 12.0 0.1 0.12 11.8 0.1 1.3 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel DUF5619 PF18505.1 AAL62952.1 - 0.1 12.6 0.9 0.23 11.5 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5619) Diphthamide_syn PF01866.17 AAL62952.1 - 0.11 12.0 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 Putative diphthamide synthesis protein SIMPL PF04402.14 AAL62952.1 - 0.13 12.7 4.6 2.1 8.8 4.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF541) PepSY PF03413.19 AAL62952.1 - 0.22 12.1 3.5 0.49 11.0 1.1 2.2 1 1 1 2 2 2 0 Peptidase propeptide and YPEB domain BPD_transp_1 PF00528.22 AAL62953.1 - 3.9e-12 46.3 17.7 3.9e-12 46.3 17.7 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 AAL62954.1 - 3e-10 40.1 20.3 3e-10 40.1 20.3 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF443 PF04276.12 AAL62954.1 - 0.0042 16.9 7.1 0.0042 16.9 7.1 2.8 2 1 0 3 3 3 1 Protein of unknown function (DUF443) TMEM252 PF15664.5 AAL62954.1 - 0.067 12.9 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 Transmembrane protein 252 family DUF5585 PF17823.1 AAL62954.1 - 0.27 10.2 0.6 0.4 9.6 0.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5585) SBP_bac_1 PF01547.25 AAL62955.1 - 7.3e-18 65.6 0.0 1.4e-17 64.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 AAL62955.1 - 1.9e-17 64.0 0.0 3e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein Pkinase PF00069.25 AAL62956.1 - 1.9e-10 40.6 0.0 2.2e-10 40.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AAL62956.1 - 4.3e-06 26.2 0.0 4.9e-06 26.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 AAL62956.1 - 0.28 10.8 0.0 0.32 10.6 0.0 1.1 1 0 0 1 1 1 0 RIO1 family Toxin_23 PF08093.11 AAL62956.1 - 0.42 10.8 3.4 1.6 8.9 3.4 2.1 1 1 0 1 1 1 0 Magi 5 toxic peptide family DUF1610 PF07754.11 AAL62957.1 - 7.8e-17 60.9 0.9 2.5e-13 49.7 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1610) zf-RING_7 PF02591.15 AAL62957.1 - 0.00011 22.3 0.7 0.23 11.7 0.1 2.2 2 0 0 2 2 2 2 C4-type zinc ribbon domain zf-ribbon_3 PF13248.6 AAL62957.1 - 0.00016 21.0 1.8 0.31 10.5 0.1 2.4 2 0 0 2 2 2 2 zinc-ribbon domain zinc_ribbon_4 PF13717.6 AAL62957.1 - 0.00044 20.1 0.7 0.00065 19.6 0.7 1.3 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_2 PF13240.6 AAL62957.1 - 0.00072 19.2 2.4 0.19 11.5 0.1 2.3 2 0 0 2 2 2 2 zinc-ribbon domain zinc_ribbon_10 PF10058.9 AAL62957.1 - 0.00075 19.2 0.3 0.39 10.5 0.1 2.1 2 0 0 2 2 2 1 Predicted integral membrane zinc-ribbon metal-binding protein TF_Zn_Ribbon PF08271.12 AAL62957.1 - 0.0019 17.7 4.2 0.014 14.9 4.2 2.0 1 1 0 1 1 1 1 TFIIB zinc-binding zf-Mss51 PF13824.6 AAL62957.1 - 0.0023 18.0 2.3 1.1 9.5 0.2 2.1 1 1 1 2 2 2 2 Zinc-finger of mitochondrial splicing suppressor 51 Zn-ribbon_8 PF09723.10 AAL62957.1 - 0.0049 17.0 2.0 0.012 15.7 2.0 1.6 1 1 0 1 1 1 1 Zinc ribbon domain zf-ISL3 PF14690.6 AAL62957.1 - 0.0065 17.1 1.9 0.34 11.6 0.1 2.2 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn_Tnp_IS1595 PF12760.7 AAL62957.1 - 0.009 16.0 4.2 0.02 14.9 4.2 1.5 1 1 0 1 1 1 1 Transposase zinc-ribbon domain Zn_ribbon_SprT PF17283.2 AAL62957.1 - 0.0096 15.8 3.7 0.026 14.4 3.7 1.6 1 1 0 1 1 1 1 SprT-like zinc ribbon domain Zn_Tnp_IS1 PF03811.13 AAL62957.1 - 0.01 15.6 1.4 0.016 14.9 1.4 1.3 1 0 0 1 1 1 0 InsA N-terminal domain Rubredoxin_2 PF18073.1 AAL62957.1 - 0.012 15.3 2.2 0.85 9.4 0.3 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain DZR PF12773.7 AAL62957.1 - 0.016 15.2 0.6 0.028 14.5 0.7 1.4 1 1 0 1 1 1 0 Double zinc ribbon zf-H2C2_2 PF13465.6 AAL62957.1 - 0.016 15.6 2.7 2 9.0 0.6 2.4 2 1 0 2 2 2 0 Zinc-finger double domain zf_UBZ PF18439.1 AAL62957.1 - 0.016 14.7 1.4 2.5 7.8 0.2 2.1 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger HypA PF01155.19 AAL62957.1 - 0.019 15.0 0.1 0.022 14.8 0.1 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2 PF00096.26 AAL62957.1 - 0.019 15.4 2.5 4.6 7.9 0.1 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type PhnA_Zn_Ribbon PF08274.12 AAL62957.1 - 0.02 14.8 0.3 1.9 8.5 0.0 2.1 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Sgf11 PF08209.11 AAL62957.1 - 0.02 14.4 1.4 0.45 10.1 0.1 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Ogr_Delta PF04606.12 AAL62957.1 - 0.021 14.8 3.8 0.31 11.0 0.2 2.2 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger tRNA-synt_1f PF01921.18 AAL62957.1 - 0.024 13.5 0.0 0.024 13.5 0.0 1.0 1 0 0 1 1 1 0 tRNA synthetases class I (K) zinc_ribbon_5 PF13719.6 AAL62957.1 - 0.032 14.0 0.7 0.05 13.4 0.7 1.3 1 0 0 1 1 1 0 zinc-ribbon domain TFIIS_C PF01096.18 AAL62957.1 - 0.036 13.9 1.2 3.7 7.5 0.1 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) OrfB_Zn_ribbon PF07282.11 AAL62957.1 - 0.039 13.9 1.8 0.092 12.7 1.8 1.5 1 1 1 2 2 2 0 Putative transposase DNA-binding domain Nudix_N_2 PF14803.6 AAL62957.1 - 0.044 13.7 1.4 8 6.5 0.1 2.2 2 0 0 2 2 2 0 Nudix N-terminal zinc_ribbon_9 PF14369.6 AAL62957.1 - 0.047 14.0 0.3 3 8.2 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon Rubredoxin PF00301.20 AAL62957.1 - 0.05 13.6 1.9 4.9 7.3 0.0 2.3 2 1 0 2 2 2 0 Rubredoxin DNA_RNApol_7kD PF03604.13 AAL62957.1 - 0.051 13.3 0.9 3.1 7.6 0.1 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-C4_Topoisom PF01396.19 AAL62957.1 - 0.069 12.9 2.8 2 8.3 0.0 2.5 3 0 0 3 3 2 0 Topoisomerase DNA binding C4 zinc finger Elf1 PF05129.13 AAL62957.1 - 0.074 13.1 0.8 0.18 11.8 0.8 1.6 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like A2L_zn_ribbon PF08792.10 AAL62957.1 - 0.084 12.6 0.9 3.1 7.6 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain PADR1 PF08063.12 AAL62957.1 - 0.092 12.5 2.2 1.5 8.6 0.3 2.1 1 1 1 2 2 2 0 PADR1 (NUC008) domain DUF3268 PF11672.8 AAL62957.1 - 0.097 13.0 0.4 0.13 12.6 0.4 1.2 1 0 0 1 1 1 0 zinc-finger-containing domain zf-TFIIB PF13453.6 AAL62957.1 - 0.097 12.0 2.2 0.2 11.0 2.2 1.5 1 1 0 1 1 1 0 Transcription factor zinc-finger DUF35_N PF12172.8 AAL62957.1 - 0.097 12.6 2.3 6.3 6.8 0.1 2.3 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Anti-TRAP PF15777.5 AAL62957.1 - 0.1 12.6 1.7 0.42 10.6 1.5 1.8 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein C1_2 PF03107.16 AAL62957.1 - 0.12 12.7 0.5 0.21 11.9 0.5 1.3 1 1 0 1 1 1 0 C1 domain zf-C2H2_3 PF13878.6 AAL62957.1 - 0.14 12.0 0.4 2.3 8.1 0.0 2.2 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO zf_C2H2_10 PF18414.1 AAL62957.1 - 0.21 11.1 2.8 4 7.0 0.2 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger DNA_ligase_ZBD PF03119.16 AAL62957.1 - 0.23 11.5 4.4 1.4 9.0 4.4 2.1 1 1 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain HalOD2 PF18547.1 AAL62957.1 - 0.25 11.3 1.9 13 5.8 0.2 2.2 1 1 1 2 2 2 0 Halobacterial output domain 2 DUF2614 PF11023.8 AAL62957.1 - 0.29 11.2 0.8 1.5 8.9 1.0 1.8 1 1 0 1 1 1 0 Zinc-ribbon containing domain UPF0547 PF10571.9 AAL62957.1 - 0.3 11.2 5.7 0.76 9.9 0.8 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 CpXC PF14353.6 AAL62957.1 - 0.35 10.9 3.3 3.8 7.6 0.2 2.1 1 1 1 2 2 2 0 CpXC protein zf-C2H2_6 PF13912.6 AAL62957.1 - 0.45 10.6 1.8 12 6.0 0.2 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger NOB1_Zn_bind PF08772.11 AAL62957.1 - 0.9 9.7 4.2 0.97 9.6 0.1 2.6 2 1 1 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like zf-IS66 PF13005.7 AAL62957.1 - 1.2 9.6 6.0 8.4 6.9 0.2 2.2 1 1 1 2 2 2 0 zinc-finger binding domain of transposase IS66 DUF3797 PF12677.7 AAL62957.1 - 1.3 9.0 5.4 3.7 7.5 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3797) zf-C2H2_4 PF13894.6 AAL62957.1 - 1.3 10.0 3.3 36 5.6 0.3 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-tcix PF14952.6 AAL62957.1 - 2.1 8.0 8.0 5.7 6.6 1.1 2.2 1 1 1 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding EF1_GNE PF00736.19 AAL62958.1 - 5.8e-15 55.2 0.0 6.5e-15 55.1 0.0 1.0 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain AAA PF00004.29 AAL62959.1 - 1.7e-99 329.4 0.0 8e-50 168.7 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 AAL62959.1 - 4.1e-37 125.7 1.3 6.8e-19 67.4 0.5 2.7 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 AAL62959.1 - 2e-29 101.6 1.3 4.1e-28 97.4 3.1 2.3 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 AAL62959.1 - 3.7e-16 59.3 0.0 2.4e-07 30.7 0.0 2.8 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain CDC48_2 PF02933.17 AAL62959.1 - 1.1e-14 53.9 0.5 3.1e-14 52.5 0.5 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.6 AAL62959.1 - 2.5e-14 53.7 0.2 0.00045 20.5 0.0 5.5 4 2 2 6 6 5 2 AAA domain TIP49 PF06068.13 AAL62959.1 - 1.6e-13 50.6 0.8 1.3e-05 24.6 0.0 3.4 3 0 0 3 3 3 2 TIP49 P-loop domain AAA_2 PF07724.14 AAL62959.1 - 3.5e-13 50.0 0.0 1.5e-07 31.7 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 AAL62959.1 - 1.3e-12 48.4 0.2 1.1e-05 25.9 0.0 3.5 2 1 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 AAL62959.1 - 2.5e-12 47.0 0.9 3.8e-05 23.7 0.1 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 AAL62959.1 - 7.3e-11 42.4 0.0 7.7e-05 22.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain UFD1 PF03152.14 AAL62959.1 - 7.8e-11 41.7 0.1 1.5e-10 40.8 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 AAA_14 PF13173.6 AAL62959.1 - 4.9e-10 39.5 0.0 6.2e-05 23.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 AAL62959.1 - 3.6e-09 36.6 0.0 0.0031 17.3 0.0 2.8 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_28 PF13521.6 AAL62959.1 - 1e-08 35.6 0.0 0.0018 18.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 AAL62959.1 - 2.7e-08 34.4 0.0 0.0059 17.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.10 AAL62959.1 - 3.1e-08 33.5 0.8 0.00011 22.1 0.1 3.3 3 0 0 3 3 2 2 Vps4 C terminal oligomerisation domain Mg_chelatase PF01078.21 AAL62959.1 - 4.8e-07 29.4 1.0 0.027 13.9 0.1 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 AAL62959.1 - 9.8e-07 28.7 0.0 0.043 13.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 AAL62959.1 - 3.7e-06 26.8 0.1 0.087 12.5 0.0 3.6 3 1 0 3 3 3 2 Sigma-54 interaction domain RNA_helicase PF00910.22 AAL62959.1 - 1.1e-05 25.8 0.0 0.25 11.8 0.0 2.6 2 0 0 2 2 2 2 RNA helicase PhoH PF02562.16 AAL62959.1 - 1.6e-05 24.4 0.5 0.2 11.1 0.0 2.7 2 0 0 2 2 2 2 PhoH-like protein Zeta_toxin PF06414.12 AAL62959.1 - 2e-05 23.9 0.8 0.22 10.8 0.0 3.0 3 0 0 3 3 3 2 Zeta toxin AAA_7 PF12775.7 AAL62959.1 - 2.6e-05 23.8 0.1 0.12 11.8 0.0 2.9 2 1 0 2 2 2 2 P-loop containing dynein motor region DUF815 PF05673.13 AAL62959.1 - 2.8e-05 23.4 0.0 0.21 10.7 0.0 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF815) TsaE PF02367.17 AAL62959.1 - 3e-05 24.0 0.0 0.46 10.5 0.0 2.6 2 1 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 AAL62959.1 - 5.5e-05 22.6 2.7 0.36 10.1 0.0 3.5 3 1 0 4 4 3 2 KaiC ABC_tran PF00005.27 AAL62959.1 - 0.0001 22.8 0.0 0.41 11.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter NACHT PF05729.12 AAL62959.1 - 0.00034 20.6 0.9 1.1 9.1 0.0 3.6 4 0 0 4 4 4 1 NACHT domain AAA_3 PF07726.11 AAL62959.1 - 0.00044 20.1 0.0 0.98 9.3 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 AAL62959.1 - 0.00071 18.7 0.0 0.81 8.7 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.6 AAL62959.1 - 0.0012 18.9 0.0 2 8.5 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF2075 PF09848.9 AAL62959.1 - 0.0016 17.7 0.0 0.67 9.1 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 AAL62959.1 - 0.0018 18.0 2.2 0.83 9.3 0.0 3.3 3 1 0 3 3 2 1 AAA domain Viral_helicase1 PF01443.18 AAL62959.1 - 0.0032 17.3 0.0 0.16 11.6 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 AAL62959.1 - 0.0032 17.3 0.0 1.5 8.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 AAL62959.1 - 0.0033 17.2 0.0 0.88 9.3 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.6 AAL62959.1 - 0.0037 17.7 0.0 4.6 7.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 AAL62959.1 - 0.0045 16.6 10.2 2.2 7.8 1.5 4.2 2 2 1 3 3 3 1 AAA domain AAA_19 PF13245.6 AAL62959.1 - 0.0046 17.3 4.6 1.2 9.5 0.2 3.4 3 1 1 4 4 3 1 AAA domain Guanylate_kin PF00625.21 AAL62959.1 - 0.0048 16.6 0.3 17 5.0 0.0 3.9 2 2 2 4 4 4 0 Guanylate kinase Molydop_binding PF01568.21 AAL62959.1 - 0.0048 16.9 0.2 0.057 13.4 0.3 2.8 3 0 0 3 3 2 1 Molydopterin dinucleotide binding domain ATPase_2 PF01637.18 AAL62959.1 - 0.0051 16.8 0.4 1.9 8.3 0.1 3.3 2 2 1 3 3 2 1 ATPase domain predominantly from Archaea Bac_DnaA PF00308.18 AAL62959.1 - 0.0083 16.0 0.0 1.9 8.2 0.0 3.1 2 1 1 3 3 2 1 Bacterial dnaA protein NB-ARC PF00931.22 AAL62959.1 - 0.012 14.8 0.0 3.4 6.8 0.0 2.7 3 0 0 3 3 2 0 NB-ARC domain T2SSE PF00437.20 AAL62959.1 - 0.014 14.4 0.0 2.6 7.0 0.0 2.8 3 0 0 3 3 2 0 Type II/IV secretion system protein TniB PF05621.11 AAL62959.1 - 0.023 14.1 0.1 5.6 6.3 0.0 3.3 3 1 0 4 4 3 0 Bacterial TniB protein AAA_29 PF13555.6 AAL62959.1 - 0.029 14.1 0.0 8.1 6.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Rad17 PF03215.15 AAL62959.1 - 0.036 14.0 0.0 17 5.3 0.0 2.9 2 1 0 2 2 2 0 Rad17 P-loop domain Cytidylate_kin PF02224.18 AAL62959.1 - 0.042 13.6 0.2 11 5.7 0.0 2.7 3 0 0 3 3 2 0 Cytidylate kinase ResIII PF04851.15 AAL62959.1 - 0.048 13.7 0.0 7 6.6 0.0 2.5 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit NTPase_1 PF03266.15 AAL62959.1 - 0.08 12.9 6.4 7.4 6.5 0.0 4.7 4 2 2 6 6 5 0 NTPase cobW PF02492.19 AAL62959.1 - 0.085 12.4 0.1 13 5.3 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IPT PF01745.16 AAL62959.1 - 0.1 12.0 0.5 2.5 7.4 0.1 2.3 2 0 0 2 2 2 0 Isopentenyl transferase AFG1_ATPase PF03969.16 AAL62959.1 - 0.1 11.4 0.0 11 4.8 0.0 2.4 2 0 0 2 2 2 0 AFG1-like ATPase SKI PF01202.22 AAL62959.1 - 0.12 12.5 0.0 22 5.1 0.0 2.8 3 0 0 3 3 2 0 Shikimate kinase MCM PF00493.23 AAL62959.1 - 0.12 11.5 0.0 15 4.6 0.0 2.5 2 0 0 2 2 2 0 MCM P-loop domain SRPRB PF09439.10 AAL62959.1 - 0.18 11.3 0.0 13 5.2 0.0 2.4 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit Roc PF08477.13 AAL62959.1 - 0.2 11.9 0.0 11 6.3 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RTX_C PF08339.10 AAL62960.1 - 0.0021 18.1 0.4 0.0022 18.1 0.4 1.1 1 0 0 1 1 1 1 RTX C-terminal domain Type2_restr_D3 PF16902.5 AAL62960.1 - 0.035 14.0 1.2 0.048 13.6 1.0 1.3 1 1 0 1 1 1 0 Type-2 restriction enzyme D3 domain HTH_12 PF08461.10 AAL62960.1 - 0.039 13.9 2.4 0.047 13.6 2.4 1.1 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain XPG_I PF00867.18 AAL62961.1 - 9.4e-28 96.4 0.0 1.7e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 AAL62961.1 - 5.6e-24 84.5 0.0 1.2e-23 83.5 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 AAL62961.1 - 5.8e-07 30.0 0.0 1.4e-06 28.8 0.0 1.8 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.7 AAL62961.1 - 0.043 13.9 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH_5 PF14520.6 AAL62961.1 - 0.059 14.0 0.0 0.24 12.0 0.0 2.0 1 0 0 1 1 1 0 Helix-hairpin-helix domain PHP_C PF13263.6 AAL62961.1 - 0.89 9.4 2.6 12 5.8 0.2 2.8 3 0 0 3 3 3 0 PHP-associated PCMT PF01135.19 AAL62963.1 - 1.1e-67 227.9 0.1 1.2e-67 227.8 0.1 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 AAL62963.1 - 5.2e-10 39.3 0.0 7.2e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 AAL62963.1 - 2.4e-08 33.4 0.0 3.2e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase GCD14 PF08704.10 AAL62963.1 - 1.4e-07 31.5 0.0 1.8e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_25 PF13649.6 AAL62963.1 - 4.2e-07 30.6 0.0 6.3e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 AAL62963.1 - 6.8e-06 27.1 0.0 1.1e-05 26.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAL62963.1 - 7.5e-05 23.3 0.0 0.00016 22.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AAL62963.1 - 8.5e-05 22.0 0.0 0.00012 21.5 0.0 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltr_RsmB-F PF01189.17 AAL62963.1 - 0.001 18.8 0.0 0.0022 17.6 0.0 1.6 1 1 1 2 2 2 1 16S rRNA methyltransferase RsmB/F CMAS PF02353.20 AAL62963.1 - 0.0038 16.5 0.0 0.0051 16.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 AAL62963.1 - 0.0073 17.0 0.0 0.011 16.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 AAL62963.1 - 0.0088 16.0 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AAL62963.1 - 0.0091 15.6 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Fibrillarin PF01269.17 AAL62963.1 - 0.0092 15.1 0.0 0.017 14.3 0.0 1.4 1 0 0 1 1 1 1 Fibrillarin Methyltransf_32 PF13679.6 AAL62963.1 - 0.026 14.5 0.0 0.038 14.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.12 AAL62963.1 - 0.071 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_23 PF13489.6 AAL62963.1 - 0.083 12.7 0.0 0.15 11.9 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain DUF1422 PF07226.11 AAL62964.1 - 0.057 13.4 0.0 0.058 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1422) tRNA-synt_2 PF00152.20 AAL62965.1 - 4.7e-79 265.7 0.0 5.5e-79 265.5 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 AAL62965.1 - 3.1e-11 43.1 1.6 5.3e-11 42.4 1.6 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 AAL62965.1 - 0.0053 16.3 0.0 1.3 8.5 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) SseB_C PF14581.6 AAL62965.1 - 0.061 13.4 0.7 0.16 12.1 0.1 2.0 2 0 0 2 2 2 0 SseB protein C-terminal domain KH_5 PF13184.6 AAL62966.1 - 0.0059 16.7 0.8 0.77 9.9 0.1 2.4 2 0 0 2 2 2 2 NusA-like KH domain Radical_SAM PF04055.21 AAL62967.1 - 1e-13 52.0 0.0 1e-12 48.7 0.0 2.5 3 0 0 3 3 3 1 Radical SAM superfamily HHH_3 PF12836.7 AAL62967.1 - 2.7e-05 24.3 0.0 6.1e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif AXE1 PF05448.12 AAL62967.1 - 0.14 10.8 0.0 0.22 10.1 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF4040 PF13244.6 AAL62968.1 - 0.97 9.6 7.1 2.6 8.3 7.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4040) PTH2 PF01981.16 AAL62969.1 - 8.9e-40 135.6 0.1 9.8e-40 135.5 0.1 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 HrpB1_HrpK PF09613.10 AAL62969.1 - 0.075 12.7 1.3 0.1 12.2 1.3 1.2 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) DUF2000 PF09391.10 AAL62969.1 - 0.11 12.4 0.0 13 5.7 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2000) CdhD PF03599.16 AAL62969.1 - 0.16 10.6 0.0 0.17 10.5 0.0 1.0 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit Peptidase_S8 PF00082.22 AAL62970.1 - 1.3e-29 103.4 0.1 2.2e-29 102.7 0.1 1.3 1 0 0 1 1 1 1 Subtilase family EF-hand_5 PF13202.6 AAL62970.1 - 0.0099 15.3 0.0 0.023 14.2 0.0 1.6 1 0 0 1 1 1 1 EF hand NUDIX PF00293.28 AAL62971.1 - 3.4e-15 56.2 0.6 3.9e-15 56.1 0.6 1.1 1 0 0 1 1 1 1 NUDIX domain PS_pyruv_trans PF04230.13 AAL62972.1 - 0.16 11.8 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide pyruvyl transferase FAD_binding_2 PF00890.24 AAL62973.1 - 4.4e-111 371.9 0.4 5.2e-111 371.7 0.4 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 AAL62973.1 - 4.2e-36 123.8 0.0 6.5e-36 123.1 0.0 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term DAO PF01266.24 AAL62973.1 - 0.0021 17.7 0.7 0.0053 16.4 0.7 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 AAL62973.1 - 0.0038 16.5 2.5 0.0065 15.7 1.1 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 AAL62973.1 - 0.036 13.3 0.2 0.65 9.2 0.1 2.6 3 0 0 3 3 3 0 Thi4 family GIDA PF01134.22 AAL62973.1 - 0.39 9.7 1.3 2.5 7.1 1.3 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 AAL62973.1 - 0.8 9.0 2.5 7.1 5.8 2.6 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Fer2_3 PF13085.6 AAL62974.1 - 1e-32 112.4 0.0 1.7e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_8 PF13183.6 AAL62974.1 - 1.8e-11 44.3 0.9 1.8e-11 44.3 0.9 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAL62974.1 - 3.5e-09 36.6 1.6 3.5e-09 36.6 1.6 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAL62974.1 - 9.2e-07 29.3 1.2 9.2e-07 29.3 1.2 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AAL62974.1 - 6.6e-06 26.6 13.8 7.6e-05 23.2 4.3 2.7 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAL62974.1 - 6.6e-06 26.2 1.8 6.6e-06 26.2 1.8 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4 PF00037.27 AAL62974.1 - 0.0001 22.0 2.0 0.0001 22.0 2.0 3.1 3 0 0 3 3 3 1 4Fe-4S binding domain Fer2 PF00111.27 AAL62974.1 - 0.00011 22.0 0.1 0.00011 22.0 0.1 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_18 PF13746.6 AAL62974.1 - 0.00068 19.8 2.1 0.2 11.8 0.1 2.6 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAL62974.1 - 0.0014 19.5 6.3 0.0017 19.3 3.5 2.4 2 1 0 2 2 2 1 4Fe-4S double cluster binding domain Fer4_4 PF12800.7 AAL62974.1 - 0.0022 18.4 0.3 0.0022 18.4 0.3 3.0 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_6 PF12837.7 AAL62974.1 - 0.0042 17.1 2.4 0.0042 17.1 2.4 2.9 3 0 0 3 3 2 1 4Fe-4S binding domain Fer4_2 PF12797.7 AAL62974.1 - 0.0059 16.6 1.3 0.0059 16.6 1.3 3.4 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_21 PF14697.6 AAL62974.1 - 0.022 14.9 0.7 0.022 14.9 0.7 2.6 3 0 0 3 3 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 AAL62974.1 - 0.025 15.5 3.9 0.025 15.5 3.9 3.0 3 0 0 3 3 2 0 4Fe-4S binding domain Sdh_cyt PF01127.22 AAL62975.1 - 5.4e-09 36.1 2.1 8.6e-09 35.5 2.0 1.5 1 1 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DctQ PF04290.12 AAL62976.1 - 0.027 14.4 1.8 0.027 14.4 1.8 2.0 1 1 1 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Sdh_cyt PF01127.22 AAL62976.1 - 0.25 11.4 8.8 0.21 11.6 6.7 1.8 1 1 1 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2892 PF11127.8 AAL62976.1 - 0.46 10.6 10.8 1.5 8.9 1.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2892) Fig1 PF12351.8 AAL62976.1 - 0.74 9.7 8.9 3 7.7 9.2 1.7 1 1 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 PCNA_C PF02747.15 AAL62977.1 - 4.2e-09 36.7 0.1 6.2e-09 36.1 0.1 1.3 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.18 AAL62977.1 - 8.7e-09 35.2 0.0 1.7e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad9 PF04139.13 AAL62977.1 - 0.00011 21.8 0.0 0.00016 21.3 0.0 1.2 1 0 0 1 1 1 1 Rad9 DUF4115 PF13464.6 AAL62977.1 - 0.15 12.3 0.0 0.41 10.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4115) ETF PF01012.21 AAL62978.1 - 2.8e-43 147.9 0.3 5.1e-43 147.1 0.1 1.5 2 0 0 2 2 2 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 AAL62978.1 - 2e-33 114.3 2.0 6.4e-33 112.6 0.6 2.2 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain TPP_enzyme_M PF00205.22 AAL62978.1 - 0.028 14.1 0.8 0.68 9.7 0.8 2.6 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain AcetDehyd-dimer PF09290.11 AAL62978.1 - 0.14 12.3 0.4 0.57 10.4 0.1 2.0 2 0 0 2 2 2 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation Cons_hypoth95 PF03602.15 AAL62978.1 - 0.69 9.5 2.6 17 5.0 0.2 2.7 3 0 0 3 3 3 0 Conserved hypothetical protein 95 ETF PF01012.21 AAL62979.1 - 4e-38 131.1 0.1 5.7e-38 130.6 0.1 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Gly_kinase PF02595.15 AAL62979.1 - 0.16 10.9 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Glycerate kinase family Fer4_2 PF12797.7 AAL62980.1 - 1.9e-08 33.9 14.0 2.7e-05 24.0 3.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 AAL62980.1 - 1.5e-07 31.8 9.8 0.00027 21.5 0.8 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain ETF_QO PF05187.13 AAL62980.1 - 1.6e-07 31.4 3.5 2.1e-07 31.0 3.5 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4 PF00037.27 AAL62980.1 - 4.5e-06 26.2 2.7 4.5e-06 26.2 2.7 3.1 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_11 PF13247.6 AAL62980.1 - 2.4e-05 24.4 8.5 3.1e-05 24.0 8.5 1.1 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAL62980.1 - 4e-05 24.5 8.7 0.002 19.0 1.2 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 AAL62980.1 - 6.3e-05 23.1 16.3 0.00013 22.1 16.4 1.4 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 AAL62980.1 - 0.00021 21.7 7.6 0.0029 18.0 0.7 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAL62980.1 - 0.00051 20.1 18.7 0.004 17.2 2.6 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain NSP11 PF06471.12 AAL62980.1 - 0.0018 16.8 1.4 0.002 16.7 1.4 1.0 1 0 0 1 1 1 1 NSP11 Fer4_4 PF12800.7 AAL62980.1 - 0.0024 18.2 1.3 0.0024 18.2 1.3 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_6 PF12837.7 AAL62980.1 - 0.0045 17.0 16.0 0.0066 16.5 2.1 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_21 PF14697.6 AAL62980.1 - 0.012 15.7 14.7 0.024 14.7 14.7 1.5 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAL62980.1 - 0.087 13.4 4.8 0.087 13.4 4.8 2.2 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 AAL62980.1 - 9.3 7.5 22.4 0.25 12.4 6.7 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain DAO PF01266.24 AAL62981.1 - 3.7e-18 66.2 1.8 1.1e-08 35.1 0.3 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 AAL62981.1 - 5.7e-12 45.4 0.5 3.6e-09 36.2 0.0 2.3 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 AAL62981.1 - 1.1e-10 41.3 0.5 6.7e-07 28.9 0.1 2.6 2 1 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.24 AAL62981.1 - 3.3e-09 36.3 2.1 1.3e-07 31.1 0.8 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 AAL62981.1 - 3.5e-09 36.8 0.2 1.1e-08 35.1 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 AAL62981.1 - 2.1e-08 33.3 2.2 6.8e-08 31.6 0.3 2.4 3 0 0 3 3 3 1 HI0933-like protein FAD_oxidored PF12831.7 AAL62981.1 - 2.2e-08 33.9 1.1 2.6e-08 33.7 0.2 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 AAL62981.1 - 3.2e-08 33.1 1.0 3.4e-07 29.8 0.0 2.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAL62981.1 - 7.3e-08 32.0 1.1 4e-06 26.3 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 AAL62981.1 - 9.2e-08 31.4 1.5 4.2e-05 22.6 0.0 2.3 1 1 1 2 2 2 2 Tryptophan halogenase Lycopene_cycl PF05834.12 AAL62981.1 - 2.9e-06 26.6 2.9 4.1e-05 22.8 2.9 2.1 1 1 0 1 1 1 1 Lycopene cyclase protein Amino_oxidase PF01593.24 AAL62981.1 - 3.4e-05 23.3 1.2 0.00019 20.9 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 AAL62981.1 - 4.5e-05 23.9 0.3 0.016 15.7 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AAL62981.1 - 0.00016 20.9 0.4 0.00026 20.2 0.4 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_9 PF13454.6 AAL62981.1 - 0.0035 17.4 1.6 0.044 13.8 1.6 2.3 1 1 0 1 1 1 1 FAD-NAD(P)-binding ApbA PF02558.16 AAL62981.1 - 0.025 14.2 0.0 0.061 13.0 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 AAL62981.1 - 0.03 14.2 1.4 0.036 14.0 0.1 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Chlorosome_CsmC PF11098.8 AAL62981.1 - 0.076 13.0 0.3 6 6.8 0.1 2.4 1 1 1 2 2 2 0 Chlorosome envelope protein C NAD_binding_7 PF13241.6 AAL62981.1 - 0.14 12.6 0.1 0.35 11.3 0.1 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding GDI PF00996.18 AAL62981.1 - 0.15 10.5 0.0 0.39 9.2 0.0 1.7 1 0 0 1 1 1 0 GDP dissociation inhibitor MoaE PF02391.17 AAL62982.1 - 3.2e-24 85.4 0.3 4.4e-24 84.9 0.3 1.1 1 0 0 1 1 1 1 MoaE protein ThiS PF02597.20 AAL62982.1 - 1.6e-18 67.1 0.0 3.3e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 ThiS family Ub-Mut7C PF14451.6 AAL62982.1 - 0.0084 15.9 0.0 0.036 13.9 0.0 2.0 2 0 0 2 2 2 1 Mut7-C ubiquitin ATPase PF06745.13 AAL62984.1 - 3.2e-68 229.5 0.5 3.7e-68 229.3 0.5 1.0 1 0 0 1 1 1 1 KaiC RecA PF00154.21 AAL62984.1 - 0.0017 17.9 0.0 0.0026 17.3 0.0 1.4 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Rad51 PF08423.11 AAL62984.1 - 0.011 15.1 0.2 0.016 14.4 0.2 1.2 1 0 0 1 1 1 0 Rad51 AAA_25 PF13481.6 AAL62984.1 - 0.013 15.1 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain MEDS PF14417.6 AAL62984.1 - 0.036 13.9 0.0 0.082 12.7 0.0 1.6 2 0 0 2 2 2 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain GvpD PF07088.11 AAL62984.1 - 0.069 11.8 0.3 0.15 10.7 0.3 1.6 1 1 0 1 1 1 0 GvpD gas vesicle protein DnaB_C PF03796.15 AAL62984.1 - 0.082 12.2 0.0 0.15 11.4 0.0 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain PAXNEB PF05625.11 AAL62984.1 - 0.091 11.9 0.1 0.13 11.4 0.1 1.1 1 0 0 1 1 1 0 PAXNEB protein HTH_24 PF13412.6 AAL62986.1 - 2.1e-08 33.6 0.9 4.3e-08 32.6 0.7 1.6 1 1 1 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 AAL62986.1 - 4e-08 33.1 0.2 6.9e-08 32.4 0.2 1.4 1 1 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_5 PF01022.20 AAL62986.1 - 1.4e-06 28.0 0.1 2.2e-06 27.4 0.1 1.3 1 1 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_23 PF13384.6 AAL62986.1 - 3e-06 26.9 0.2 3.9e-06 26.5 0.2 1.2 1 0 0 1 1 1 1 Homeodomain-like domain MarR_2 PF12802.7 AAL62986.1 - 5e-06 26.3 0.7 8.1e-05 22.4 0.2 2.0 1 1 1 2 2 2 1 MarR family Fe_dep_repress PF01325.19 AAL62986.1 - 1e-05 25.7 0.0 1.2e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain Rrf2 PF02082.20 AAL62986.1 - 1.1e-05 25.7 0.1 3.4e-05 24.1 0.1 1.7 1 1 1 2 2 2 1 Transcriptional regulator HTH_11 PF08279.12 AAL62986.1 - 1.2e-05 25.2 0.3 1.7e-05 24.7 0.3 1.2 1 0 0 1 1 1 1 HTH domain HTH_9 PF08221.11 AAL62986.1 - 1.4e-05 25.1 0.0 1.8e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TrmB PF01978.19 AAL62986.1 - 2.5e-05 24.0 0.3 4.6e-05 23.2 0.2 1.4 1 1 1 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_28 PF13518.6 AAL62986.1 - 4.4e-05 23.5 0.2 6e-05 23.1 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain MarR PF01047.22 AAL62986.1 - 7.6e-05 22.6 0.0 0.00011 22.0 0.0 1.2 1 0 0 1 1 1 1 MarR family HTH_29 PF13551.6 AAL62986.1 - 8.3e-05 22.5 0.1 0.00012 22.0 0.1 1.2 1 0 0 1 1 1 1 Winged helix-turn helix Sigma70_r4_2 PF08281.12 AAL62986.1 - 9.6e-05 22.0 0.2 0.00013 21.6 0.2 1.2 1 0 0 1 1 1 1 Sigma-70, region 4 TFIIE_alpha PF02002.17 AAL62986.1 - 0.00014 21.7 0.1 0.00018 21.3 0.1 1.2 1 0 0 1 1 1 1 TFIIE alpha subunit HTH_IclR PF09339.10 AAL62986.1 - 0.00016 21.4 0.1 0.00032 20.5 0.0 1.5 1 1 1 2 2 2 1 IclR helix-turn-helix domain HTH_AsnC-type PF13404.6 AAL62986.1 - 0.00029 20.6 0.7 0.00047 19.9 0.7 1.3 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain GntR PF00392.21 AAL62986.1 - 0.00037 20.1 1.3 0.00096 18.8 1.2 1.7 1 1 1 2 2 2 1 Bacterial regulatory proteins, gntR family z-alpha PF02295.17 AAL62986.1 - 0.0012 18.8 0.1 0.0017 18.4 0.1 1.2 1 0 0 1 1 1 1 Adenosine deaminase z-alpha domain HTH_27 PF13463.6 AAL62986.1 - 0.0023 18.4 0.2 0.0095 16.4 0.1 1.7 1 1 1 2 2 2 1 Winged helix DNA-binding domain AbiEi_4 PF13338.6 AAL62986.1 - 0.0034 17.5 0.5 0.0056 16.8 0.3 1.5 1 1 1 2 2 2 1 Transcriptional regulator, AbiEi antitoxin DUF977 PF06163.11 AAL62986.1 - 0.0073 16.2 0.1 0.0077 16.2 0.1 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF977) UPF0175 PF03683.13 AAL62986.1 - 0.0091 15.7 0.1 0.012 15.3 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0175) DUF1013 PF06242.11 AAL62986.1 - 0.0098 15.9 0.0 0.012 15.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1013) PheRS_DBD1 PF18552.1 AAL62986.1 - 0.014 15.1 0.1 0.021 14.6 0.1 1.5 1 1 0 1 1 1 0 PheRS DNA binding domain 1 HTH_36 PF13730.6 AAL62986.1 - 0.017 15.1 0.1 0.085 12.8 0.0 1.9 1 1 1 2 2 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 AAL62986.1 - 0.022 14.3 0.3 0.03 13.8 0.3 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 Terminase_5 PF06056.12 AAL62986.1 - 0.03 14.2 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) CENP-B_N PF04218.13 AAL62986.1 - 0.042 13.5 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain SelB-wing_3 PF09107.11 AAL62986.1 - 0.047 13.3 0.0 0.066 12.9 0.0 1.2 1 0 0 1 1 1 0 Elongation factor SelB, winged helix HTH_47 PF16221.5 AAL62986.1 - 0.051 13.1 0.1 0.078 12.5 0.1 1.4 1 1 0 1 1 1 0 winged helix-turn-helix HTH_50 PF18024.1 AAL62986.1 - 0.053 13.1 0.1 0.39 10.4 0.1 2.0 1 1 1 2 2 2 0 Helix-turn-helix domain Replic_Relax PF13814.6 AAL62986.1 - 0.064 13.3 0.0 0.079 13.0 0.0 1.2 1 0 0 1 1 1 0 Replication-relaxation Sigma70_r1_1 PF03979.14 AAL62986.1 - 0.066 13.3 0.0 0.087 12.9 0.0 1.1 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 Crp PF00325.20 AAL62986.1 - 0.07 12.8 0.2 0.11 12.2 0.2 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family PCI PF01399.27 AAL62986.1 - 0.073 13.6 0.0 0.077 13.5 0.0 1.1 1 0 0 1 1 1 0 PCI domain CtsR_C PF17727.1 AAL62986.1 - 0.088 12.9 0.4 2.5 8.3 0.1 2.0 1 1 1 2 2 2 0 CtsR C-terminal dimerization domain BLACT_WH PF17778.1 AAL62986.1 - 0.089 12.8 0.0 0.17 11.9 0.0 1.6 2 0 0 2 2 1 0 Beta-lactamase associated winged helix domain TnsD PF15978.5 AAL62986.1 - 0.092 11.7 0.1 0.11 11.5 0.1 1.1 1 0 0 1 1 1 0 Tn7-like transposition protein D LexA_DNA_bind PF01726.16 AAL62986.1 - 0.094 12.5 0.2 0.15 11.8 0.2 1.4 1 1 0 1 1 1 0 LexA DNA binding domain Abhydrolase_1 PF00561.20 AAL62986.1 - 0.18 11.4 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ribosomal_S7 PF00177.21 AAL62988.1 - 2.3e-44 150.6 0.1 2.8e-44 150.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Rep_fac_C PF08542.11 AAL62989.1 - 2.7e-18 66.2 0.2 7e-18 64.8 0.1 1.8 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA PF00004.29 AAL62989.1 - 3.3e-16 59.9 0.0 7.9e-16 58.7 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 AAL62989.1 - 1.4e-15 57.4 0.0 5e-11 42.6 0.1 2.4 1 1 1 2 2 2 2 DNA polymerase III, delta subunit RuvB_N PF05496.12 AAL62989.1 - 6e-09 35.8 0.0 1.4e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 AAL62989.1 - 7.1e-08 33.0 0.1 0.00053 20.4 0.0 2.9 2 1 1 3 3 3 2 AAA ATPase domain AAA_14 PF13173.6 AAL62989.1 - 9.5e-07 28.9 0.0 7.5e-06 26.0 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 AAL62989.1 - 9.9e-07 29.0 0.3 3.3e-06 27.3 0.3 1.9 1 0 0 1 1 1 1 AAA C-terminal domain AAA_22 PF13401.6 AAL62989.1 - 2.5e-06 27.8 0.2 0.067 13.5 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_3 PF07726.11 AAL62989.1 - 1.3e-05 25.1 0.0 2.1e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 AAL62989.1 - 2.6e-05 24.2 0.0 5.7e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_18 PF13238.6 AAL62989.1 - 4.4e-05 24.0 0.1 0.0007 20.1 0.0 2.4 1 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 AAL62989.1 - 0.00011 22.0 0.0 0.00022 21.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 AAL62989.1 - 0.00012 21.6 0.0 0.0023 17.3 0.0 2.5 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 AAL62989.1 - 0.00016 21.7 0.1 0.00062 19.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 AAL62989.1 - 0.00017 21.2 0.0 0.00032 20.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 AAL62989.1 - 0.00035 20.6 0.0 0.0051 16.8 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 AAL62989.1 - 0.00035 20.1 0.0 0.35 10.3 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_30 PF13604.6 AAL62989.1 - 0.0012 18.6 0.2 0.0067 16.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 AAL62989.1 - 0.0024 18.0 0.0 0.0052 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 AAL62989.1 - 0.0025 17.6 0.0 0.0043 16.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_11 PF13086.6 AAL62989.1 - 0.0025 17.6 0.0 0.01 15.6 0.0 1.7 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.22 AAL62989.1 - 0.0044 17.4 0.0 0.0098 16.3 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_7 PF12775.7 AAL62989.1 - 0.0055 16.2 0.0 0.012 15.1 0.0 1.6 2 0 0 2 2 1 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 AAL62989.1 - 0.0058 16.4 0.0 0.019 14.7 0.0 1.9 1 1 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 AAL62989.1 - 0.0059 15.9 0.0 0.018 14.3 0.0 1.7 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_19 PF13245.6 AAL62989.1 - 0.0077 16.6 0.1 0.039 14.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 AAL62989.1 - 0.0083 15.9 0.2 0.16 11.7 0.0 2.2 1 1 1 2 2 2 1 DEAD/DEAH box helicase TIP49_C PF17856.1 AAL62989.1 - 0.011 15.8 0.2 0.029 14.5 0.2 1.7 1 0 0 1 1 1 0 TIP49 AAA-lid domain TniB PF05621.11 AAL62989.1 - 0.014 14.8 0.1 0.35 10.2 0.0 2.2 1 1 0 2 2 2 0 Bacterial TniB protein AAA_28 PF13521.6 AAL62989.1 - 0.028 14.6 0.0 0.057 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 AAL62989.1 - 0.05 12.8 0.0 0.86 8.8 0.0 2.2 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 AAL62989.1 - 0.06 13.1 0.0 0.085 12.6 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 AAL62989.1 - 0.066 13.7 0.0 0.23 11.9 0.0 2.0 1 1 0 1 1 1 0 ABC transporter T2SSE PF00437.20 AAL62989.1 - 0.076 12.1 0.0 0.38 9.8 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein ATPase_2 PF01637.18 AAL62989.1 - 0.084 12.8 0.0 0.18 11.7 0.0 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 AAL62989.1 - 0.23 10.5 0.0 0.39 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 HSCB_C PF07743.13 AAL62989.1 - 3 8.4 6.9 1.7 9.2 0.0 3.7 4 2 0 4 4 3 0 HSCB C-terminal oligomerisation domain AAA PF00004.29 AAL62990.1 - 9.1e-16 58.5 0.0 2.3e-14 53.9 0.0 2.5 1 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AAL62990.1 - 3e-08 34.3 0.2 2.4e-07 31.3 0.1 2.3 2 1 0 2 2 1 1 AAA ATPase domain DNA_pol3_delta PF06144.13 AAL62990.1 - 2.5e-07 30.7 0.1 1.4e-05 24.9 0.0 2.8 3 0 0 3 3 3 1 DNA polymerase III, delta subunit AAA_22 PF13401.6 AAL62990.1 - 3.4e-07 30.6 1.0 0.00024 21.4 0.0 3.9 2 1 2 4 4 4 1 AAA domain RuvB_N PF05496.12 AAL62990.1 - 4.8e-06 26.4 0.0 2.9e-05 23.9 0.0 2.3 2 1 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 AAL62990.1 - 5.5e-06 26.4 0.3 4.6e-05 23.4 0.1 2.4 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 AAL62990.1 - 7e-06 26.4 0.0 5.2e-05 23.6 0.0 2.3 2 0 0 2 2 2 1 RNA helicase Rad17 PF03215.15 AAL62990.1 - 7.1e-06 26.1 0.0 0.00011 22.1 0.0 2.7 2 1 0 2 2 1 1 Rad17 P-loop domain AAA_14 PF13173.6 AAL62990.1 - 1.8e-05 24.8 0.0 0.00014 21.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 AAL62990.1 - 1.9e-05 25.2 0.1 7.4e-05 23.3 0.0 2.1 2 0 0 2 2 1 1 AAA domain RFC1 PF08519.12 AAL62990.1 - 3.2e-05 24.2 0.0 5.9e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain Zeta_toxin PF06414.12 AAL62990.1 - 4.7e-05 22.8 0.0 0.0001 21.7 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 AAL62990.1 - 9.3e-05 22.6 0.0 0.0004 20.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain Bac_DnaA PF00308.18 AAL62990.1 - 0.00019 21.4 0.2 0.0023 17.8 0.0 2.6 2 1 0 2 2 2 1 Bacterial dnaA protein AAA_7 PF12775.7 AAL62990.1 - 0.00026 20.5 0.0 0.00042 19.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_2 PF07724.14 AAL62990.1 - 0.00027 21.1 0.0 0.00063 19.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 AAL62990.1 - 0.00067 19.0 0.0 0.0014 17.9 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 AAL62990.1 - 0.0007 19.4 0.1 0.0032 17.2 0.0 2.0 2 1 0 2 2 2 1 IstB-like ATP binding protein NACHT PF05729.12 AAL62990.1 - 0.00071 19.5 0.1 0.016 15.1 0.0 2.8 2 1 0 3 3 3 1 NACHT domain NTPase_1 PF03266.15 AAL62990.1 - 0.00081 19.3 0.0 0.0024 17.8 0.0 1.8 2 0 0 2 2 1 1 NTPase AAA_assoc_2 PF16193.5 AAL62990.1 - 0.0009 19.5 0.2 0.004 17.5 0.0 2.2 2 0 0 2 2 1 1 AAA C-terminal domain DUF815 PF05673.13 AAL62990.1 - 0.0012 18.0 0.0 0.0043 16.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_28 PF13521.6 AAL62990.1 - 0.0017 18.7 0.0 0.0072 16.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 AAL62990.1 - 0.0022 17.6 0.0 0.008 15.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 AAL62990.1 - 0.0023 18.4 0.0 0.0068 16.9 0.0 2.0 2 1 0 2 2 1 1 ABC transporter RsgA_GTPase PF03193.16 AAL62990.1 - 0.0025 17.8 0.0 0.0054 16.7 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase TsaE PF02367.17 AAL62990.1 - 0.0029 17.6 0.0 0.0061 16.5 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 AAL62990.1 - 0.0047 17.4 0.1 0.018 15.4 0.0 2.1 2 0 0 2 2 1 1 AAA domain NB-ARC PF00931.22 AAL62990.1 - 0.0058 15.8 0.0 0.61 9.2 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_30 PF13604.6 AAL62990.1 - 0.0071 16.1 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAL62990.1 - 0.013 15.3 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRP54 PF00448.22 AAL62990.1 - 0.02 14.5 0.0 0.23 11.0 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain T2SSE PF00437.20 AAL62990.1 - 0.021 13.9 0.0 0.043 12.9 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein MMR_HSR1 PF01926.23 AAL62990.1 - 0.024 14.7 0.0 0.065 13.3 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_3 PF07726.11 AAL62990.1 - 0.024 14.5 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HEAT_2 PF13646.6 AAL62990.1 - 0.027 14.8 0.7 1.1 9.7 0.0 2.5 2 0 0 2 2 2 0 HEAT repeats AAA_19 PF13245.6 AAL62990.1 - 0.042 14.2 0.0 0.088 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 AAL62990.1 - 0.043 13.6 0.1 0.097 12.4 0.0 1.6 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 AAL62990.1 - 0.045 13.1 0.0 0.098 12.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 AAL62990.1 - 0.059 13.1 0.0 0.098 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 AAL62990.1 - 0.063 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AFG1_ATPase PF03969.16 AAL62990.1 - 0.08 11.8 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase MeaB PF03308.16 AAL62990.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Sigma54_activat PF00158.26 AAL62990.1 - 0.11 12.2 0.0 0.49 10.1 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain cobW PF02492.19 AAL62990.1 - 0.12 11.9 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF3195 PF11424.8 AAL62991.1 - 6.5e-45 151.1 6.3 7.8e-45 150.8 6.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3195) Cdc6_C PF09079.11 AAL62992.1 - 6.4e-19 67.7 0.0 1.7e-18 66.3 0.0 1.8 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_22 PF13401.6 AAL62992.1 - 5.4e-09 36.4 0.0 1.2e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAL62992.1 - 1.7e-05 25.3 0.2 4.9e-05 23.8 0.1 1.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 AAL62992.1 - 0.049 13.3 0.0 0.083 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 AAL62992.1 - 0.055 13.9 0.0 0.14 12.5 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AAL62992.1 - 0.081 12.9 0.1 0.3 11.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 AAL62992.1 - 0.09 13.1 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain HTH_5 PF01022.20 AAL62993.1 - 2.6e-10 40.0 0.1 2.4e-09 36.9 0.0 2.1 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 AAL62993.1 - 2.3e-08 33.9 1.4 7.5e-08 32.3 0.1 2.1 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_24 PF13412.6 AAL62993.1 - 2.9e-05 23.5 0.1 5.4e-05 22.7 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 AAL62993.1 - 8.7e-05 22.6 0.6 0.00015 21.8 0.6 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.19 AAL62993.1 - 0.00017 21.4 0.0 0.00029 20.6 0.0 1.4 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_29 PF13551.6 AAL62993.1 - 0.00019 21.4 0.2 0.00027 20.9 0.2 1.2 1 0 0 1 1 1 1 Winged helix-turn helix MarR PF01047.22 AAL62993.1 - 0.00063 19.6 0.1 0.001 18.9 0.1 1.3 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.20 AAL62993.1 - 0.00081 19.7 0.1 0.0012 19.2 0.1 1.4 1 1 0 1 1 1 1 Transcriptional regulator HTH_Crp_2 PF13545.6 AAL62993.1 - 0.0029 17.5 0.3 0.0055 16.7 0.2 1.5 1 1 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_34 PF13601.6 AAL62993.1 - 0.0096 16.1 0.1 0.014 15.5 0.1 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_IclR PF09339.10 AAL62993.1 - 0.027 14.3 0.5 0.067 13.0 0.1 1.8 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_27 PF13463.6 AAL62993.1 - 0.069 13.7 0.8 0.17 12.4 0.1 1.8 1 1 1 2 2 2 0 Winged helix DNA-binding domain NucS PF01939.16 AAL62994.1 - 0.00041 19.8 0.1 0.00057 19.3 0.1 1.3 1 0 0 1 1 1 1 Endonuclease NucS DUF4143 PF13635.6 AAL62994.1 - 0.0025 18.0 0.0 0.0051 17.0 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4143) UPF0102 PF02021.17 AAL62994.1 - 0.0062 16.8 0.1 0.01 16.1 0.1 1.5 1 0 0 1 1 1 1 Uncharacterised protein family UPF0102 DUF234 PF03008.14 AAL62994.1 - 0.064 13.7 0.0 0.15 12.5 0.0 1.6 2 0 0 2 2 2 0 Archaea bacterial proteins of unknown function IF-2B PF01008.17 AAL62995.1 - 7.8e-77 258.3 0.3 9.6e-77 258.0 0.3 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family YycI PF09648.10 AAL62996.1 - 0.012 15.2 0.1 0.015 14.9 0.1 1.1 1 0 0 1 1 1 0 YycH protein DUF4883 PF16224.5 AAL62996.1 - 0.077 13.2 0.0 0.095 13.0 0.0 1.1 1 0 0 1 1 1 0 DOmain of unknown function (DUF4883) Methyltr_RsmB-F PF01189.17 AAL62997.1 - 9e-24 84.2 0.0 1.6e-23 83.4 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F PUA PF01472.20 AAL62997.1 - 1.1e-15 57.3 3.3 2.5e-15 56.2 3.3 1.6 1 0 0 1 1 1 1 PUA domain Methyltr_RsmF_N PF17125.5 AAL62997.1 - 0.00012 22.5 0.0 0.039 14.4 0.0 2.4 2 0 0 2 2 2 1 N-terminal domain of 16S rRNA methyltransferase RsmF ADH_zinc_N PF00107.26 AAL62997.1 - 0.014 15.4 0.1 0.21 11.5 0.0 2.4 2 1 0 2 2 2 0 Zinc-binding dehydrogenase Methyltransf_31 PF13847.6 AAL62997.1 - 0.03 14.1 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain UPF0113 PF03657.13 AAL62997.1 - 0.046 14.0 0.2 0.084 13.2 0.2 1.4 1 0 0 1 1 1 0 UPF0113 PUA domain Methyltransf_25 PF13649.6 AAL62997.1 - 0.058 14.1 0.0 0.13 13.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.14 AAL62997.1 - 0.065 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_15 PF09445.10 AAL62997.1 - 0.066 12.8 0.0 0.097 12.2 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase DUF4428 PF14471.6 AAL62998.1 - 0.0037 17.2 4.2 0.0037 17.2 4.2 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4428) ADD_ATRX PF17981.1 AAL62998.1 - 0.046 13.6 4.0 0.046 13.6 4.0 1.9 2 1 0 2 2 2 0 Cysteine Rich ADD domain DNA_RNApol_7kD PF03604.13 AAL62998.1 - 0.078 12.7 6.3 5.1 6.9 0.1 3.0 1 1 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-UDP PF14569.6 AAL62998.1 - 1.7 8.8 9.0 2.2e+02 2.0 9.1 2.3 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-H2C2_2 PF13465.6 AAL62998.1 - 5.8 7.5 8.4 2.6 8.6 0.2 3.2 3 0 0 3 3 3 0 Zinc-finger double domain DUF3268 PF11672.8 AAL62998.1 - 8.4 6.8 10.1 2.3e+02 2.1 10.1 2.1 1 1 0 1 1 1 0 zinc-finger-containing domain AMMECR1 PF01871.17 AAL62999.1 - 8.7e-43 145.8 0.0 1e-42 145.6 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 DUF3040 PF11239.8 AAL63001.1 - 0.15 12.4 5.8 0.18 12.1 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) NfeD PF01957.18 AAL63002.1 - 3.1e-10 40.3 0.0 3.1e-10 40.3 0.0 2.6 3 0 0 3 3 3 1 NfeD-like C-terminal, partner-binding SDH_sah PF01972.16 AAL63002.1 - 0.00019 20.5 0.1 0.00019 20.5 0.1 1.6 2 0 0 2 2 2 1 Serine dehydrogenase proteinase Band_7 PF01145.25 AAL63003.1 - 6e-34 117.6 2.6 8.1e-34 117.2 2.6 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 AAL63003.1 - 0.00024 20.9 0.2 0.001 18.9 0.0 2.0 1 1 0 2 2 2 1 SPFH domain-Band 7 family pPIWI_RE_REase PF18154.1 AAL63003.1 - 0.031 14.3 0.8 0.085 12.8 0.2 1.9 2 0 0 2 2 2 0 REase associating with pPIWI_RE DUF4713 PF15831.5 AAL63003.1 - 0.19 12.2 4.9 0.38 11.2 4.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4713) HemY_N PF07219.13 AAL63003.1 - 7.4 6.8 7.3 20 5.4 1.5 2.3 2 0 0 2 2 2 0 HemY protein N-terminus ApoLp-III PF07464.11 AAL63004.1 - 0.00027 21.0 7.9 0.00033 20.8 7.9 1.1 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) V-ATPase_G_2 PF16999.5 AAL63004.1 - 0.00046 20.6 13.7 0.00095 19.6 13.2 1.7 1 1 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit Muted PF14942.6 AAL63004.1 - 0.0036 17.6 8.6 0.0053 17.1 8.6 1.3 1 0 0 1 1 1 1 Organelle biogenesis, Muted-like protein V-ATPase_G PF03179.15 AAL63004.1 - 0.0038 17.7 13.2 0.0045 17.5 5.5 2.2 1 1 1 2 2 2 1 Vacuolar (H+)-ATPase G subunit SIMPL PF04402.14 AAL63004.1 - 0.015 15.8 4.5 0.017 15.5 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF541) Nnf1 PF03980.14 AAL63004.1 - 0.023 15.1 6.7 0.043 14.2 6.7 1.6 1 1 0 1 1 1 0 Nnf1 VWA_3 PF13768.6 AAL63004.1 - 0.023 14.6 0.2 0.031 14.2 0.2 1.3 1 1 0 1 1 1 0 von Willebrand factor type A domain Phage_Mu_Gam PF07352.12 AAL63004.1 - 0.026 14.4 16.2 0.41 10.5 8.4 2.1 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein DDHD PF02862.17 AAL63004.1 - 0.06 13.5 0.1 0.061 13.5 0.1 1.1 1 0 0 1 1 1 0 DDHD domain MRP-S27 PF10037.9 AAL63004.1 - 0.093 11.6 7.5 0.1 11.4 7.5 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 DctP PF03480.13 AAL63004.1 - 0.15 11.3 2.9 0.17 11.2 2.9 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 TBCC_N PF16752.5 AAL63004.1 - 0.16 12.4 8.8 2.5 8.5 3.5 2.1 1 1 1 2 2 2 0 Tubulin-specific chaperone C N-terminal domain Prominin PF05478.11 AAL63004.1 - 0.31 9.0 5.5 0.34 8.8 5.5 1.1 1 0 0 1 1 1 0 Prominin DUF948 PF06103.11 AAL63004.1 - 0.36 11.1 5.3 3.2 8.1 0.2 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) HSP70 PF00012.20 AAL63004.1 - 0.36 9.0 9.5 0.39 8.8 9.5 1.1 1 0 0 1 1 1 0 Hsp70 protein ISG65-75 PF11727.8 AAL63004.1 - 0.4 9.9 13.4 0.51 9.5 13.4 1.0 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF1664 PF07889.12 AAL63004.1 - 0.54 10.3 8.3 0.76 9.8 7.7 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Spore_GerAC PF05504.11 AAL63004.1 - 0.98 9.6 10.6 3.4 7.8 3.5 2.1 1 1 1 2 2 2 0 Spore germination B3/ GerAC like, C-terminal Pox_RNA_Pol_19 PF05320.12 AAL63004.1 - 1.1 9.2 11.2 0.98 9.4 6.0 1.9 1 1 1 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit MCU PF04678.13 AAL63004.1 - 1.6 8.8 4.8 2.1 8.4 4.8 1.3 1 0 0 1 1 1 0 Mitochondrial calcium uniporter LMBR1 PF04791.16 AAL63004.1 - 1.8 7.4 6.1 2.1 7.1 6.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2228 PF10228.9 AAL63004.1 - 2.4 7.8 6.9 2.3 7.9 6.0 1.4 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2228) Nore1-SARAH PF16517.5 AAL63004.1 - 2.7 8.0 8.6 1.1 9.2 4.1 2.4 2 0 0 2 2 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain DUF4065 PF13274.6 AAL63004.1 - 2.7 8.9 8.8 3 8.8 8.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4065) DUF4168 PF13767.6 AAL63004.1 - 3.7 8.8 11.4 15 6.8 11.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4168) DUF1492 PF07374.11 AAL63004.1 - 3.9 7.7 10.1 0.21 11.8 2.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1492) HSCB_C PF07743.13 AAL63004.1 - 4.1 8.0 12.6 16 6.0 5.8 2.6 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain HK97-gp10_like PF04883.12 AAL63004.1 - 4.6 8.3 9.8 4.5 8.3 4.8 2.7 1 1 1 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component PdaC PF13739.6 AAL63004.1 - 7.3 7.6 10.5 9.3 7.3 2.6 2.2 1 1 1 2 2 2 0 Deacetylase PdaC Atrophin-1 PF03154.15 AAL63004.1 - 8.2 4.6 7.3 8.1 4.6 7.3 1.2 1 0 0 1 1 1 0 Atrophin-1 family vATP-synt_AC39 PF01992.16 AAL63005.1 - 4.7e-14 52.7 2.3 6.9e-14 52.1 2.3 1.2 1 1 0 1 1 1 1 ATP synthase (C/AC39) subunit Alpha_Helical PF18489.1 AAL63005.1 - 0.13 12.5 0.4 0.66 10.2 0.0 2.1 2 0 0 2 2 2 0 Alpha helical domain ATP-synt_C PF00137.21 AAL63006.1 - 2.5e-19 69.3 14.8 2.5e-19 69.3 14.8 1.8 2 0 0 2 2 2 1 ATP synthase subunit C DUF3094 PF11293.8 AAL63006.1 - 0.12 12.1 1.7 0.84 9.4 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) CdvA PF18822.1 AAL63007.1 - 0.01 15.6 1.3 0.01 15.6 1.3 1.0 1 0 0 1 1 1 0 CdvA-like coiled-coil domain dCache_2 PF08269.11 AAL63007.1 - 0.066 12.4 0.4 0.067 12.3 0.4 1.0 1 0 0 1 1 1 0 Cache domain Apolipoprotein PF01442.18 AAL63007.1 - 0.074 12.9 0.0 0.079 12.8 0.0 1.0 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain ATP-synt_D PF01813.17 AAL63008.1 - 1.9e-40 138.8 11.2 2.1e-40 138.6 11.2 1.0 1 0 0 1 1 1 1 ATP synthase subunit D GPAT_N PF14829.6 AAL63008.1 - 0.0018 18.2 0.1 0.005 16.8 0.0 1.8 2 0 0 2 2 2 1 Glycerol-3-phosphate acyltransferase N-terminal Cep57_CLD_2 PF14197.6 AAL63008.1 - 0.024 14.7 2.3 0.024 14.7 2.3 2.0 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 AMIN PF11741.8 AAL63008.1 - 0.043 13.9 0.2 0.088 13.0 0.1 1.5 2 0 0 2 2 2 0 AMIN domain Rx_N PF18052.1 AAL63008.1 - 0.12 12.7 3.9 0.86 9.9 0.3 2.6 2 1 0 2 2 2 0 Rx N-terminal domain MMR_HSR1 PF01926.23 AAL63009.1 - 5e-16 58.8 0.3 1.6e-13 50.7 0.0 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 AAL63009.1 - 1.4e-12 47.9 0.0 2.4e-12 47.1 0.0 1.4 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 AAL63009.1 - 3.9e-11 42.7 1.5 6.8e-05 22.4 0.1 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B Dynamin_N PF00350.23 AAL63009.1 - 4.1e-08 33.5 0.1 0.00031 20.8 0.0 3.1 2 1 1 3 3 3 1 Dynamin family GTP_EFTU PF00009.27 AAL63009.1 - 5.3e-05 22.8 0.3 0.0012 18.4 0.1 2.7 2 2 1 3 3 3 1 Elongation factor Tu GTP binding domain cobW PF02492.19 AAL63009.1 - 0.00086 18.9 0.1 0.046 13.3 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.21 AAL63009.1 - 0.0015 18.0 0.2 0.094 12.2 0.0 2.2 1 1 1 2 2 2 1 ADP-ribosylation factor family Ras PF00071.22 AAL63009.1 - 0.0026 17.4 0.0 2.3 7.8 0.0 2.2 2 0 0 2 2 2 2 Ras family AIG1 PF04548.16 AAL63009.1 - 0.0031 16.9 0.1 0.016 14.5 0.0 1.9 2 0 0 2 2 2 1 AIG1 family PduV-EutP PF10662.9 AAL63009.1 - 0.01 15.6 0.0 0.2 11.4 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1_Xtn PF16897.5 AAL63009.1 - 0.016 15.2 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AAA_18 PF13238.6 AAL63009.1 - 0.017 15.7 0.0 0.041 14.4 0.0 1.9 2 1 0 2 2 2 0 AAA domain MeaB PF03308.16 AAL63009.1 - 0.055 12.4 0.1 0.65 8.9 0.0 2.1 1 1 1 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF1139 PF06599.11 AAL63009.1 - 0.059 12.8 0.0 0.079 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1139) Mrr_cat PF04471.12 AAL63011.1 - 9.2e-06 25.7 0.0 1.2e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Restriction endonuclease NERD PF08378.11 AAL63011.1 - 9.4e-06 26.1 0.0 1.6e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Nuclease-related domain Imm51 PF15595.6 AAL63011.1 - 0.013 15.4 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 51 Hjc PF01870.18 AAL63011.1 - 0.037 14.0 0.0 0.058 13.4 0.0 1.3 1 0 0 1 1 1 0 Archaeal holliday junction resolvase (hjc) UPF0102 PF02021.17 AAL63011.1 - 0.04 14.1 0.0 0.056 13.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0102 DpnII PF04556.12 AAL63011.1 - 0.057 12.7 0.0 0.075 12.3 0.0 1.2 1 0 0 1 1 1 0 DpnII restriction endonuclease Pyr_redox_2 PF07992.14 AAL63012.1 - 4.2e-11 42.6 1.6 3.5e-10 39.6 1.6 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AAL63012.1 - 2.6e-07 30.1 0.1 0.00056 19.1 1.2 3.0 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_3 PF13738.6 AAL63012.1 - 1.6e-05 24.3 4.4 0.0021 17.4 0.2 3.3 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AAL63012.1 - 3.8e-05 23.1 0.6 0.002 17.4 0.7 2.6 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.6 AAL63012.1 - 0.00041 20.5 1.8 0.055 13.7 1.5 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 AAL63012.1 - 0.0016 18.9 2.7 2.3 8.8 0.9 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AAL63012.1 - 0.015 14.7 0.1 0.052 12.9 0.2 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 AAL63012.1 - 0.059 12.5 1.2 0.16 11.0 0.9 1.8 1 1 1 2 2 2 0 Glucose inhibited division protein A NAD_binding_7 PF13241.6 AAL63012.1 - 0.17 12.3 2.3 0.35 11.3 0.1 2.5 3 0 0 3 3 3 0 Putative NAD(P)-binding PGM_PMM_I PF02878.16 AAL63013.1 - 7e-30 103.5 0.1 1.1e-29 102.9 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 AAL63013.1 - 1.3e-19 70.7 0.1 4.5e-19 69.0 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 AAL63013.1 - 2.4e-19 69.6 0.0 4.7e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 AAL63013.1 - 2.5e-11 43.6 0.0 6.2e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF763 PF05559.11 AAL63014.1 - 1.7e-118 395.4 0.0 1.9e-118 395.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF763) OMPdecase PF00215.24 AAL63015.1 - 2.8e-14 53.2 0.1 5.2e-13 49.1 0.1 2.0 1 1 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family OTCace_N PF02729.21 AAL63016.1 - 1.3e-46 158.3 0.0 1.8e-46 157.8 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 AAL63016.1 - 1.6e-28 99.8 0.0 2.8e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Acetyltransf_1 PF00583.25 AAL63017.1 - 6.8e-19 68.2 0.1 8.3e-19 68.0 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAL63017.1 - 1.5e-11 44.5 0.1 2.3e-11 43.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAL63017.1 - 4.4e-10 39.6 0.1 7.8e-10 38.8 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AAL63017.1 - 9.6e-10 38.6 0.2 1.6e-09 37.9 0.2 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAL63017.1 - 3.4e-08 33.3 0.1 5.4e-08 32.7 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 AAL63017.1 - 0.00013 22.7 0.0 0.00017 22.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AAL63017.1 - 0.00014 22.0 0.2 0.00096 19.3 0.2 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 AAL63017.1 - 0.0003 20.5 0.0 0.00041 20.0 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4821 PF16092.5 AAL63017.1 - 0.0098 15.5 0.0 0.014 15.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4821) Acetyltransf_18 PF18014.1 AAL63017.1 - 0.092 12.6 0.0 3.8 7.4 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 AAL63017.1 - 0.16 11.5 0.0 0.33 10.5 0.0 1.6 1 1 0 1 1 1 0 GNAT acetyltransferase T2SSE PF00437.20 AAL63019.1 - 2.4e-35 122.0 0.0 3.6e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 AAL63019.1 - 0.00022 20.9 0.0 0.00059 19.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_7 PF12775.7 AAL63019.1 - 0.00031 20.3 0.0 0.0006 19.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_23 PF13476.6 AAL63019.1 - 0.0019 18.8 0.0 0.0033 18.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 AAL63019.1 - 0.0021 18.6 0.0 0.0044 17.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_28 PF13521.6 AAL63019.1 - 0.0033 17.7 0.1 0.008 16.4 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AAL63019.1 - 0.0042 17.4 0.0 0.0093 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.18 AAL63019.1 - 0.0072 15.7 0.1 0.015 14.6 0.1 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_19 PF13245.6 AAL63019.1 - 0.01 16.2 0.1 0.031 14.6 0.1 1.7 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 AAL63019.1 - 0.012 15.7 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 AAL63019.1 - 0.028 14.3 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase TrwB_AAD_bind PF10412.9 AAL63019.1 - 0.031 13.2 0.0 0.047 12.6 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain PduV-EutP PF10662.9 AAL63019.1 - 0.049 13.4 0.0 0.087 12.6 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 AAL63019.1 - 0.053 13.1 0.1 0.089 12.4 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 AAL63019.1 - 0.057 13.8 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.6 AAL63019.1 - 0.062 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 AAL63019.1 - 0.079 12.7 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 AAL63019.1 - 0.081 12.3 0.1 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MobB PF03205.14 AAL63019.1 - 0.12 12.3 0.2 0.23 11.4 0.2 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.12 AAL63019.1 - 0.12 12.3 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.17 AAL63019.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Septin PF00735.18 AAL63019.1 - 0.18 11.0 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_24 PF13479.6 AAL63019.1 - 0.18 11.5 0.1 0.42 10.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 AAL63019.1 - 0.2 11.1 0.0 0.36 10.2 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein ABC2_membrane_3 PF12698.7 AAL63020.1 - 1.3 8.1 5.7 8.2 5.4 6.2 1.8 2 0 0 2 2 2 0 ABC-2 family transporter protein TGT PF01702.18 AAL63021.1 - 1.3e-62 212.0 0.0 1.7e-62 211.7 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase DUF5591 PF17884.1 AAL63021.1 - 2.7e-09 37.1 0.0 6.7e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5591) PAC2 PF09754.9 AAL63022.1 - 1.7e-31 109.9 0.0 2e-31 109.7 0.0 1.0 1 0 0 1 1 1 1 PAC2 family DUF3618 PF12277.8 AAL63022.1 - 0.61 10.4 4.2 1 9.7 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3618) TFIIE_alpha PF02002.17 AAL63023.1 - 9e-07 28.7 0.9 9e-07 28.7 0.9 1.6 2 0 0 2 2 2 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.12 AAL63023.1 - 0.001 18.5 1.6 0.0027 17.2 1.6 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding PhnA_Zn_Ribbon PF08274.12 AAL63023.1 - 0.003 17.5 0.7 1.2 9.2 0.1 2.3 2 0 0 2 2 2 1 PhnA Zinc-Ribbon zinc_ribbon_4 PF13717.6 AAL63023.1 - 0.0049 16.8 0.8 0.019 14.9 0.8 2.0 1 1 0 1 1 1 1 zinc-ribbon domain Rad50_zn_hook PF04423.14 AAL63023.1 - 0.0064 16.3 0.1 0.026 14.3 0.1 2.1 1 0 0 1 1 1 1 Rad50 zinc hook motif Ogr_Delta PF04606.12 AAL63023.1 - 0.014 15.3 0.1 2.3 8.3 0.1 2.4 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Phage_rep_org_N PF09681.10 AAL63023.1 - 0.016 15.1 0.2 0.032 14.1 0.2 1.6 1 1 0 1 1 1 0 N-terminal phage replisome organiser (Phage_rep_org_N) zinc_ribbon_2 PF13240.6 AAL63023.1 - 0.025 14.3 0.5 2.2 8.1 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain HTH_9 PF08221.11 AAL63023.1 - 0.028 14.5 0.0 0.071 13.2 0.0 1.6 2 0 0 2 2 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain DNA_ligase_ZBD PF03119.16 AAL63023.1 - 0.029 14.4 1.1 0.31 11.1 0.3 2.3 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain ADK_lid PF05191.14 AAL63023.1 - 0.036 14.1 1.5 0.062 13.3 1.5 1.4 1 0 0 1 1 1 0 Adenylate kinase, active site lid zinc-ribbons_6 PF07191.12 AAL63023.1 - 0.062 13.3 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbons A2L_zn_ribbon PF08792.10 AAL63023.1 - 0.067 12.9 0.6 2.6 7.8 0.0 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-TFIIB PF13453.6 AAL63023.1 - 0.072 12.4 0.1 4.3 6.7 0.0 2.3 2 0 0 2 2 2 0 Transcription factor zinc-finger DUF4428 PF14471.6 AAL63023.1 - 0.077 12.9 0.1 6 6.9 0.0 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4428) zf-C2H2_3 PF13878.6 AAL63023.1 - 0.078 12.8 3.3 0.38 10.6 0.6 2.4 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO HypA PF01155.19 AAL63023.1 - 0.083 12.9 0.3 0.09 12.8 0.3 1.4 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 AAL63023.1 - 0.083 12.9 0.4 0.21 11.6 0.4 1.6 1 1 0 1 1 1 0 Double zinc ribbon DUF4423 PF14394.6 AAL63023.1 - 0.095 12.4 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) zf-ACC PF17848.1 AAL63023.1 - 0.12 12.4 1.2 3.6 7.7 0.0 2.6 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain Aida_N PF08910.10 AAL63023.1 - 0.17 12.3 0.4 0.57 10.6 0.0 1.9 2 0 0 2 2 2 0 Aida N-terminus DUF1610 PF07754.11 AAL63023.1 - 0.2 11.7 2.1 1.1 9.2 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) TrmB PF01978.19 AAL63023.1 - 0.22 11.4 0.1 0.22 11.4 0.1 2.1 3 0 0 3 3 2 0 Sugar-specific transcriptional regulator TrmB zf-Di19 PF05605.12 AAL63023.1 - 0.38 11.1 1.7 5.3 7.4 0.1 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RRN7 PF11781.8 AAL63023.1 - 0.46 10.2 0.1 0.46 10.2 0.1 2.5 3 0 0 3 3 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-HIT PF04438.16 AAL63023.1 - 0.69 9.8 5.2 1.3 9.0 1.1 2.1 2 0 0 2 2 2 0 HIT zinc finger Zn_Tnp_IS1595 PF12760.7 AAL63023.1 - 0.98 9.4 4.4 10 6.2 0.2 2.3 1 1 1 2 2 2 0 Transposase zinc-ribbon domain HTH_Crp_2 PF13545.6 AAL63023.1 - 2 8.4 6.7 0.88 9.6 1.0 2.4 2 1 1 3 3 2 0 Crp-like helix-turn-helix domain zf-ribbon_3 PF13248.6 AAL63023.1 - 2.3 7.8 4.8 10 5.7 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain GTP-bdg_M PF16360.5 AAL63024.1 - 7.3e-17 61.7 3.0 1.4e-16 60.8 3.0 1.5 1 0 0 1 1 1 1 GTP-binding GTPase Middle Region GTP-bdg_N PF13167.6 AAL63024.1 - 9.3e-17 61.5 0.0 2.5e-16 60.1 0.0 1.8 1 0 0 1 1 1 1 GTP-binding GTPase N-terminal MMR_HSR1 PF01926.23 AAL63024.1 - 1.4e-15 57.4 0.0 3.3e-15 56.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AAL63024.1 - 1.3e-05 24.8 0.0 2.4e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 AAL63024.1 - 5e-05 22.9 0.0 0.022 14.3 0.0 2.6 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 AAL63024.1 - 0.00059 19.8 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 AAL63024.1 - 0.001 19.0 0.0 0.67 9.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase cobW PF02492.19 AAL63024.1 - 0.0028 17.3 0.1 0.13 11.9 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 AAL63024.1 - 0.033 14.2 0.0 0.11 12.6 0.0 1.8 2 0 0 2 2 2 0 Dynamin family PduV-EutP PF10662.9 AAL63024.1 - 0.033 13.9 0.1 1.1 9.0 0.1 2.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation T2SSE PF00437.20 AAL63024.1 - 0.045 12.8 0.0 0.089 11.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein SRPRB PF09439.10 AAL63024.1 - 0.061 12.7 0.1 0.11 12.0 0.1 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_28 PF13521.6 AAL63024.1 - 0.14 12.4 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain HTH_3 PF01381.22 AAL63025.1 - 8.7e-14 51.3 2.3 6e-13 48.6 0.7 2.1 2 0 0 2 2 2 1 Helix-turn-helix HTH_31 PF13560.6 AAL63025.1 - 4.7e-08 33.3 0.8 1.1e-07 32.1 0.5 1.7 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 AAL63025.1 - 1.7e-07 31.2 1.1 1.4e-06 28.2 0.3 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_25 PF13413.6 AAL63025.1 - 2.9e-07 30.2 2.3 1.1e-05 25.2 0.4 2.7 2 1 0 2 2 2 1 Helix-turn-helix domain Arc_trans_TRASH PF08394.10 AAL63025.1 - 0.0017 18.6 1.2 0.0026 18.1 1.2 1.3 1 0 0 1 1 1 1 Archaeal TRASH domain MqsA_antitoxin PF15731.5 AAL63025.1 - 0.0067 16.5 2.0 0.0073 16.4 0.1 2.0 3 0 0 3 3 3 1 Antitoxin component of bacterial toxin-antitoxin system, MqsA HTH_37 PF13744.6 AAL63025.1 - 0.019 14.9 0.1 0.041 13.8 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 AAL63025.1 - 0.065 13.0 0.7 0.24 11.3 0.0 2.1 2 1 0 2 2 2 0 Homeodomain-like domain CENP-B_N PF04218.13 AAL63025.1 - 0.11 12.2 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain TGT_C2 PF14810.6 AAL63026.1 - 2.9e-15 56.2 0.1 4.7e-15 55.5 0.1 1.3 1 0 0 1 1 1 1 Patch-forming domain C2 of tRNA-guanine transglycosylase PUA PF01472.20 AAL63026.1 - 3.1e-14 52.7 0.4 5.6e-14 51.9 0.4 1.4 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 AAL63026.1 - 0.0002 21.5 0.2 0.001 19.3 0.0 2.0 2 0 0 2 2 2 1 UPF0113 PUA domain TruB-C_2 PF09157.11 AAL63026.1 - 0.0097 15.9 0.1 0.051 13.6 0.0 2.0 2 0 0 2 2 2 1 Pseudouridine synthase II TruB, C-terminal TruB_C PF09142.11 AAL63026.1 - 0.075 12.8 1.0 0.23 11.3 1.0 1.8 1 1 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal Sen15 PF09631.10 AAL63027.1 - 0.00058 20.1 0.2 0.00074 19.8 0.2 1.4 1 1 0 1 1 1 1 Sen15 protein tRNA_int_endo PF01974.17 AAL63027.1 - 0.025 14.6 0.0 0.12 12.5 0.0 1.8 1 1 0 1 1 1 0 tRNA intron endonuclease, catalytic C-terminal domain LSM PF01423.22 AAL63028.1 - 6.7e-22 77.0 0.2 7.5e-22 76.8 0.2 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 AAL63028.1 - 0.00039 20.5 0.0 0.00047 20.2 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF150_C PF17384.2 AAL63028.1 - 0.021 14.9 0.0 0.029 14.5 0.0 1.2 1 0 0 1 1 1 0 RimP C-terminal SH3 domain Hfq PF17209.3 AAL63028.1 - 0.035 13.8 0.0 0.044 13.4 0.0 1.2 1 0 0 1 1 1 0 Hfq protein DUF1320 PF07030.12 AAL63028.1 - 0.052 13.7 0.0 0.065 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1320) MarC PF01914.17 AAL63029.1 - 6.5e-31 107.3 16.9 8.5e-31 106.9 16.9 1.1 1 0 0 1 1 1 1 MarC family integral membrane protein ParA PF10609.9 AAL63030.1 - 5.4e-83 278.2 0.0 6.3e-83 278.0 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 AAL63030.1 - 3.2e-10 40.2 0.0 8.8e-10 38.7 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 AAL63030.1 - 0.00047 19.4 2.4 0.0011 18.2 1.6 1.9 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.6 AAL63030.1 - 0.0024 17.8 0.4 0.0061 16.5 0.2 1.7 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 AAL63030.1 - 0.007 15.7 0.1 0.01 15.2 0.1 1.4 1 1 0 1 1 1 1 ATPase MipZ MeaB PF03308.16 AAL63030.1 - 0.025 13.6 0.5 0.043 12.8 0.5 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Fer4_NifH PF00142.18 AAL63030.1 - 0.026 14.0 0.2 0.077 12.4 0.2 1.7 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family APS_kinase PF01583.20 AAL63030.1 - 0.062 13.2 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_25 PF13481.6 AAL63030.1 - 0.09 12.3 0.1 0.17 11.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 AAL63030.1 - 0.11 11.7 0.3 0.17 11.0 0.3 1.2 1 0 0 1 1 1 0 NB-ARC domain dCMP_cyt_deam_1 PF00383.23 AAL63031.1 - 6.2e-18 64.5 0.0 7.3e-18 64.3 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 AAL63031.1 - 4.6e-09 36.6 0.0 8.3e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 AAL63031.1 - 0.00071 19.2 0.7 0.096 12.3 0.2 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases MafB19-deam PF14437.6 AAL63031.1 - 0.058 13.1 0.0 0.069 12.9 0.0 1.1 1 0 0 1 1 1 0 MafB19-like deaminase EndIII_4Fe-2S PF10576.9 AAL63032.1 - 0.013 15.8 3.0 0.025 14.9 3.0 1.5 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III DUF2007 PF09413.10 AAL63032.1 - 0.03 14.5 0.0 0.091 12.9 0.0 1.8 1 0 0 1 1 1 0 Putative prokaryotic signal transducing protein DsbC_N PF10411.9 AAL63032.1 - 0.096 12.2 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Disulfide bond isomerase protein N-terminus adh_short_C2 PF13561.6 AAL63033.1 - 2.9e-52 177.6 0.0 4.1e-52 177.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAL63033.1 - 1.9e-40 138.4 0.0 2.3e-40 138.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAL63033.1 - 8e-07 29.1 0.0 1.2e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 AAL63033.1 - 0.0059 16.9 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Spore_IV_A PF09547.10 AAL63033.1 - 0.0073 15.3 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Stage IV sporulation protein A (spore_IV_A) DUF4853 PF16145.5 AAL63033.1 - 0.034 14.3 0.0 10 6.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4853) F420_oxidored PF03807.17 AAL63033.1 - 0.052 14.1 0.1 0.13 12.9 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.6 AAL63033.1 - 0.065 13.1 0.0 0.09 12.7 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Shikimate_DH PF01488.20 AAL63033.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Rnk_N PF14760.6 AAL63033.1 - 8.6 6.9 8.0 14 6.2 0.0 2.8 3 0 0 3 3 3 0 Rnk N-terminus SHMT PF00464.19 AAL63034.1 - 9e-74 248.4 0.1 1.2e-73 248.1 0.1 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 AAL63034.1 - 3.7e-06 26.4 0.0 9.3e-06 25.0 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 AAL63034.1 - 2.4e-05 23.8 0.0 6e-05 22.5 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 AAL63034.1 - 0.00038 19.9 0.0 0.00064 19.1 0.0 1.6 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 AAL63034.1 - 0.013 14.5 0.0 0.12 11.3 0.0 2.0 1 1 0 1 1 1 0 Aminotransferase class-V SelA PF03841.13 AAL63034.1 - 0.13 11.2 0.4 0.99 8.3 0.1 2.4 2 1 0 2 2 2 0 L-seryl-tRNA selenium transferase MoaC PF01967.21 AAL63035.1 - 1.4e-16 60.8 0.1 1.6e-09 38.0 0.0 3.5 1 1 1 3 3 3 3 MoaC family TF_Zn_Ribbon PF08271.12 AAL63036.1 - 4.1e-09 35.8 0.8 7.9e-09 34.9 0.8 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding TFIIS_C PF01096.18 AAL63036.1 - 8.6e-05 22.3 1.0 0.096 12.6 0.4 2.3 2 0 0 2 2 2 2 Transcription factor S-II (TFIIS) OrfB_Zn_ribbon PF07282.11 AAL63036.1 - 0.0016 18.3 0.4 0.0031 17.4 0.4 1.5 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Zn_Tnp_IS1595 PF12760.7 AAL63036.1 - 0.0018 18.2 0.7 0.0018 18.2 0.7 2.0 2 0 0 2 2 2 1 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.10 AAL63036.1 - 0.01 15.5 4.3 0.18 11.6 4.3 2.3 1 1 0 1 1 1 0 A2L zinc ribbon domain DZR PF12773.7 AAL63036.1 - 0.013 15.5 1.1 0.025 14.6 0.6 1.7 1 1 0 1 1 1 0 Double zinc ribbon Lar_restr_allev PF14354.6 AAL63036.1 - 0.016 15.6 0.6 0.035 14.5 0.6 1.6 1 1 0 1 1 1 0 Restriction alleviation protein Lar zinc_ribbon_2 PF13240.6 AAL63036.1 - 0.021 14.6 3.4 4.3 7.2 0.1 2.8 2 0 0 2 2 2 0 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 AAL63036.1 - 0.03 14.3 2.4 0.69 9.9 2.4 2.4 1 1 0 1 1 1 0 PhnA Zinc-Ribbon RNA_POL_M_15KD PF02150.16 AAL63036.1 - 0.031 14.1 1.8 0.18 11.7 1.8 2.1 1 1 0 1 1 1 0 RNA polymerases M/15 Kd subunit Zn-ribbon_8 PF09723.10 AAL63036.1 - 0.033 14.3 5.3 1.7 8.8 0.3 2.9 3 0 0 3 3 3 0 Zinc ribbon domain Rubredoxin_2 PF18073.1 AAL63036.1 - 0.039 13.7 2.9 0.38 10.5 0.1 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain YueH PF14166.6 AAL63036.1 - 0.058 13.3 0.4 0.099 12.5 0.4 1.4 1 0 0 1 1 1 0 YueH-like protein zf-ribbon_3 PF13248.6 AAL63036.1 - 0.064 12.7 4.8 1.5 8.3 0.3 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf_C2H2_10 PF18414.1 AAL63036.1 - 0.1 12.1 3.4 4.6 6.9 0.3 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger UPF0547 PF10571.9 AAL63036.1 - 0.11 12.6 5.2 1.3 9.1 5.2 2.4 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 RNA_pol_L_2 PF13656.6 AAL63036.1 - 0.12 12.1 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain zf_UBZ PF18439.1 AAL63036.1 - 0.2 11.3 2.4 5.6 6.6 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-RRN7 PF11781.8 AAL63036.1 - 0.48 10.2 3.7 4.5 7.1 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DUF4428 PF14471.6 AAL63036.1 - 2.1 8.3 5.5 1.3 9.0 0.6 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4428) ADK_lid PF05191.14 AAL63036.1 - 4.3 7.4 8.0 5.1 7.2 5.2 2.3 2 1 0 2 2 1 0 Adenylate kinase, active site lid FMN_dh PF01070.18 AAL63037.1 - 1.6e-19 70.1 3.6 8e-17 61.3 3.6 2.2 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 AAL63037.1 - 7.2e-05 22.1 1.0 0.00023 20.4 0.3 2.0 2 0 0 2 2 2 1 Conserved region in glutamate synthase IMPDH PF00478.25 AAL63037.1 - 0.00055 19.0 5.7 0.019 14.0 0.3 3.0 2 1 1 3 3 3 2 IMP dehydrogenase / GMP reductase domain Ribosomal_L2_C PF03947.18 AAL63038.1 - 4.2e-40 136.8 2.6 6.1e-40 136.3 2.6 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 AAL63038.1 - 3.6e-11 42.9 0.0 1e-10 41.4 0.0 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Ribosomal_S17e PF00833.18 AAL63039.1 - 1.5e-17 63.6 0.1 1.7e-17 63.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal S17 FKBP26_C PF18046.1 AAL63040.1 - 1.8e-11 44.0 0.1 3.7e-11 42.9 0.1 1.6 1 0 0 1 1 1 1 FKBP26_C-terminal FKBP_C PF00254.28 AAL63040.1 - 1.5e-06 28.4 0.0 3.7e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase CorC_HlyC PF03471.17 AAL63040.1 - 0.042 13.8 0.6 3.1 7.9 0.0 3.0 3 0 0 3 3 3 0 Transporter associated domain ArsA_HSP20 PF17886.1 AAL63040.1 - 0.12 11.9 0.2 0.36 10.4 0.0 1.8 2 0 0 2 2 2 0 HSP20-like domain found in ArsA Proteasome PF00227.26 AAL63041.1 - 3.1e-54 183.4 0.6 3.5e-54 183.2 0.6 1.0 1 0 0 1 1 1 1 Proteasome subunit NUDIX PF00293.28 AAL63044.1 - 4.5e-11 42.9 0.1 5.3e-11 42.7 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain Enolase_C PF00113.22 AAL63046.1 - 2.2e-55 188.0 0.0 2.9e-55 187.6 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 AAL63046.1 - 4.6e-26 91.5 0.1 9.3e-26 90.5 0.0 1.6 2 0 0 2 2 2 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 AAL63046.1 - 1.6e-10 41.0 0.0 2.5e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 AAL63046.1 - 0.011 14.9 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus HTH_1 PF00126.27 AAL63047.1 - 1.5e-14 53.7 0.0 2.2e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_29 PF13551.6 AAL63047.1 - 0.0012 18.8 0.0 0.0019 18.2 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_8 PF02954.19 AAL63047.1 - 0.008 15.9 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family HTH_11 PF08279.12 AAL63047.1 - 0.011 15.7 0.1 0.05 13.5 0.1 1.9 1 1 0 1 1 1 0 HTH domain DUF505 PF04458.12 AAL63047.1 - 0.013 13.9 0.1 2.1 6.6 0.0 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF505) DUF4817 PF16087.5 AAL63047.1 - 0.016 15.0 0.0 2 8.3 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain (DUF4817) NUMOD1 PF07453.13 AAL63047.1 - 0.031 14.5 0.1 0.071 13.4 0.1 1.6 1 0 0 1 1 1 0 NUMOD1 domain HTH_28 PF13518.6 AAL63047.1 - 0.039 14.1 0.0 0.072 13.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 AAL63047.1 - 0.042 13.7 0.1 0.099 12.5 0.0 1.6 2 0 0 2 2 2 0 Homeodomain-like domain REV1_C PF16727.5 AAL63047.1 - 0.072 13.5 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 DNA repair protein REV1 C-terminal domain Mob_synth_C PF06463.13 AAL63048.1 - 1.2e-25 89.9 0.0 1.8e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 AAL63048.1 - 3.4e-25 89.4 0.0 5.4e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 AAL63048.1 - 2e-05 24.7 0.0 3.8e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 AAL63048.1 - 0.00014 22.2 0.0 0.00026 21.2 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain HMGL-like PF00682.19 AAL63048.1 - 0.076 12.6 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 HMGL-like Pkinase PF00069.25 AAL63049.1 - 4.5e-39 134.4 0.0 1.1e-38 133.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AAL63049.1 - 8.9e-23 80.9 0.0 1.9e-22 79.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 AAL63049.1 - 0.0015 17.9 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 AAL63049.1 - 0.0073 15.9 0.2 4 7.0 0.1 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 AAL63049.1 - 0.21 10.9 0.0 0.32 10.3 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FHA PF00498.26 AAL63050.1 - 1.8e-12 47.4 0.1 2.6e-12 46.9 0.1 1.3 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 AAL63050.1 - 2e-12 47.3 0.0 2.7e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zinc_ribbon_2 PF13240.6 AAL63050.1 - 1e-05 25.1 3.0 1.7e-05 24.4 3.0 1.3 1 0 0 1 1 1 1 zinc-ribbon domain zf-RanBP PF00641.18 AAL63050.1 - 3.9e-05 22.9 0.4 5.4e-05 22.4 0.4 1.2 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zf-ribbon_3 PF13248.6 AAL63050.1 - 0.00042 19.6 3.4 0.00078 18.8 3.4 1.3 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 AAL63050.1 - 0.0047 16.9 0.2 0.0064 16.5 0.2 1.2 1 0 0 1 1 1 1 Double zinc ribbon TF_Zn_Ribbon PF08271.12 AAL63050.1 - 0.006 16.1 2.5 0.015 14.8 2.5 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding Vps36-NZF-N PF16988.5 AAL63050.1 - 0.051 13.0 2.8 0.46 9.9 2.8 2.1 1 1 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Prok-RING_1 PF14446.6 AAL63050.1 - 0.075 13.0 1.2 0.12 12.3 1.2 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Zf_RING PF16744.5 AAL63050.1 - 0.091 12.9 0.3 0.14 12.3 0.3 1.2 1 0 0 1 1 1 0 KIAA1045 RING finger zf-nanos PF05741.13 AAL63050.1 - 0.45 10.8 3.6 1.1 9.5 0.3 2.2 1 1 1 2 2 2 0 Nanos RNA binding domain RecR PF02132.15 AAL63050.1 - 0.71 9.5 2.5 4.6 6.9 0.1 2.5 2 1 1 3 3 3 0 RecR protein zf-Sec23_Sec24 PF04810.15 AAL63050.1 - 0.9 9.6 5.4 0.69 10.0 0.4 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-tcix PF14952.6 AAL63050.1 - 1.8 8.2 5.7 18 5.1 5.2 2.3 1 1 1 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding Ribosomal_S2 PF00318.20 AAL63051.1 - 4.4e-26 91.4 0.0 3.6e-17 62.3 0.0 2.0 1 1 1 2 2 2 2 Ribosomal protein S2 PHP PF02811.19 AAL63051.1 - 0.029 14.7 0.0 0.051 13.9 0.0 1.3 1 0 0 1 1 1 0 PHP domain SRPRB PF09439.10 AAL63051.1 - 0.047 13.1 0.0 0.069 12.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Peripla_BP_4 PF13407.6 AAL63051.1 - 0.14 11.7 0.1 0.19 11.3 0.1 1.1 1 0 0 1 1 1 0 Periplasmic binding protein domain Memo PF01875.17 AAL63052.1 - 4.6e-78 262.1 0.0 5.2e-78 261.9 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein LigB PF02900.18 AAL63052.1 - 1.1e-06 28.0 0.0 1.4e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase DUF5488 PF17590.2 AAL63052.1 - 0.063 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5488) PK PF00224.21 AAL63053.1 - 1.3e-67 228.2 0.0 1.6e-67 227.9 0.0 1.0 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 AAL63053.1 - 2.3e-12 47.2 0.0 2.5e-11 43.9 0.0 2.5 3 0 0 3 3 3 1 Pyruvate kinase, alpha/beta domain Beta-Casp PF10996.8 AAL63054.1 - 1.1e-25 90.0 0.0 5.7e-25 87.7 0.0 2.3 3 0 0 3 3 3 1 Beta-Casp domain RMMBL PF07521.12 AAL63054.1 - 6.4e-17 61.2 0.1 2.9e-16 59.1 0.1 2.2 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_6 PF16661.5 AAL63054.1 - 3.8e-15 55.8 0.0 9.2e-15 54.6 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 AAL63054.1 - 3.9e-12 46.1 0.0 1e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain KH_7 PF17214.3 AAL63054.1 - 6.4e-12 45.3 3.5 9.6e-12 44.7 0.8 2.8 4 0 0 4 4 4 1 KH domain Lactamase_B PF00753.27 AAL63054.1 - 1.9e-11 44.3 0.2 1.2e-10 41.8 0.2 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily DRMBL PF07522.14 AAL63054.1 - 0.14 12.3 0.0 0.37 11.0 0.0 1.7 1 0 0 1 1 1 0 DNA repair metallo-beta-lactamase tRNA-synt_1e PF01406.19 AAL63055.1 - 2.9e-114 381.5 0.0 6.4e-114 380.4 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 AAL63055.1 - 1.2e-10 40.7 0.4 2.7e-06 26.4 0.1 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1f PF01921.18 AAL63055.1 - 2.1e-09 36.8 0.4 7.6e-06 25.1 0.2 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (K) DALR_2 PF09190.11 AAL63055.1 - 1.8e-08 34.7 0.0 5.4e-08 33.2 0.0 1.9 1 0 0 1 1 1 1 DALR domain tRNA-synt_1 PF00133.22 AAL63055.1 - 2.6e-08 32.6 0.0 6.1e-08 31.4 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) MIEAP PF16026.5 AAL63055.1 - 0.095 12.9 0.1 0.42 10.8 0.0 2.0 1 1 1 2 2 2 0 Mitochondria-eating protein Helicase_C_3 PF13625.6 AAL63055.1 - 0.11 12.7 0.4 0.24 11.6 0.4 1.5 1 0 0 1 1 1 0 Helicase conserved C-terminal domain PaREP1 PF05942.11 AAL63056.1 - 4.5e-26 91.0 2.1 5.7e-26 90.7 2.1 1.2 1 0 0 1 1 1 1 Archaeal PaREP1/PaREP8 family ATPase_2 PF01637.18 AAL63057.1 - 5.3e-59 200.0 0.0 6.5e-59 199.7 0.0 1.1 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 AAL63057.1 - 0.00059 20.3 0.0 0.001 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AAL63057.1 - 0.0025 18.1 0.0 0.0047 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AAL63057.1 - 0.0048 16.6 0.0 0.017 14.8 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 AAL63057.1 - 0.0084 16.2 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AAL63057.1 - 0.019 15.1 0.0 0.035 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 AAL63057.1 - 0.024 15.1 0.0 0.033 14.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 AAL63057.1 - 0.066 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 AAL63057.1 - 0.084 13.3 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 RNA helicase Cupin_2 PF07883.11 AAL63059.1 - 0.15 11.8 0.0 2.6 7.8 0.0 2.9 2 0 0 2 2 2 0 Cupin domain DUF3244 PF11589.8 AAL63059.1 - 0.18 11.9 3.2 2 8.6 0.1 3.6 3 2 1 4 4 4 0 Domain of unknown function (DUF3244) DUF5633 PF18656.1 AAL63059.1 - 0.2 11.6 0.2 0.5 10.3 0.2 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5633) CarboxypepD_reg PF13620.6 AAL63059.1 - 2.4 8.5 14.6 1.6 9.1 0.1 5.6 5 0 0 5 5 5 0 Carboxypeptidase regulatory-like domain CarboxypepD_reg PF13620.6 AAL63060.1 - 9.3e-06 25.8 17.3 0.54 10.6 0.2 7.1 5 1 1 6 6 6 3 Carboxypeptidase regulatory-like domain Big_1 PF02369.16 AAL63060.1 - 0.0056 16.7 0.9 0.0056 16.7 0.9 6.9 9 0 0 9 9 9 1 Bacterial Ig-like domain (group 1) DUF824 PF05688.11 AAL63060.1 - 0.0093 15.8 0.2 0.079 12.8 0.1 2.7 2 0 0 2 2 2 1 Salmonella repeat of unknown function (DUF824) AMMECR1 PF01871.17 AAL63061.1 - 1.4e-08 34.5 0.0 1.8e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 DUF3809 PF12723.7 AAL63061.1 - 0.047 14.0 0.0 0.12 12.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3809) DUF1525 PF07511.11 AAL63062.1 - 0.0084 16.2 0.5 0.015 15.4 0.3 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1525) Thioredoxin_3 PF13192.6 AAL63062.1 - 0.02 14.9 0.1 0.046 13.8 0.1 1.6 1 0 0 1 1 1 0 Thioredoxin domain CYTH PF01928.21 AAL63063.1 - 5.6e-38 130.7 1.4 6.4e-38 130.5 1.4 1.0 1 0 0 1 1 1 1 CYTH domain Glyoxalase_5 PF14696.6 AAL63063.1 - 0.045 13.9 0.0 0.1 12.8 0.0 1.7 2 0 0 2 2 2 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal DNA_ligase_A_M PF01068.21 AAL63064.1 - 9.1e-66 221.4 0.0 1.4e-65 220.8 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 AAL63064.1 - 4.1e-37 128.2 0.0 3.8e-36 125.0 0.0 2.1 1 1 1 2 2 2 2 DNA ligase N terminus DNA_ligase_A_C PF04679.15 AAL63064.1 - 2.2e-23 82.7 0.0 9.7e-23 80.6 0.0 2.0 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 AAL63064.1 - 4.4e-07 30.3 0.0 6.8e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 RNA ligase DNA_ligase_OB_2 PF14743.6 AAL63064.1 - 0.058 13.4 0.2 0.3 11.1 0.0 2.4 4 0 0 4 4 4 0 DNA ligase OB-like domain PocR PF10114.9 AAL63064.1 - 0.18 11.5 0.0 0.43 10.3 0.0 1.5 1 0 0 1 1 1 0 Sensory domain found in PocR DUF3361 PF11841.8 AAL63064.1 - 0.23 11.4 0.0 23 4.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) Lzipper-MIP1 PF14389.6 AAL63065.1 - 0.028 14.7 0.6 0.028 14.7 0.6 1.8 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 PfkB PF00294.24 AAL63066.1 - 8.5e-54 182.9 1.8 1.1e-53 182.6 1.8 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DMPK_coil PF08826.10 AAL63067.1 - 0.11 12.6 0.5 0.17 12.0 0.5 1.3 1 0 0 1 1 1 0 DMPK coiled coil domain like zf-CCCH_2 PF14608.6 AAL63067.1 - 2.4 8.8 5.7 14 6.3 0.6 2.8 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger NTP_transferase PF00483.23 AAL63068.1 - 2.6e-21 76.3 0.0 3.5e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AAL63068.1 - 3.6e-08 33.9 0.0 3.9e-08 33.8 0.0 1.3 1 1 0 1 1 1 1 MobA-like NTP transferase domain CdvA PF18822.1 AAL63069.1 - 0.00057 19.7 9.6 0.0021 17.9 1.6 3.1 2 1 2 4 4 3 2 CdvA-like coiled-coil domain SHOCT PF09851.9 AAL63069.1 - 0.003 17.2 4.8 0.003 17.2 4.8 3.1 3 0 0 3 3 3 1 Short C-terminal domain Uso1_p115_C PF04871.13 AAL63069.1 - 0.13 12.7 6.3 0.056 13.8 2.8 1.9 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF3232 PF11554.8 AAL63070.1 - 0.00029 21.2 1.7 0.11 12.8 0.2 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3232) COG5 PF10392.9 AAL63070.1 - 0.00035 20.8 2.0 0.00069 19.8 1.0 1.9 1 1 1 2 2 2 1 Golgi transport complex subunit 5 Syntaxin PF00804.25 AAL63070.1 - 0.011 15.4 2.2 0.012 15.3 1.2 1.6 1 1 1 2 2 1 0 Syntaxin MscS_porin PF12795.7 AAL63070.1 - 0.012 15.2 3.2 0.014 15.0 0.7 2.1 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain FapA PF03961.13 AAL63070.1 - 0.023 13.3 3.9 0.027 13.1 3.9 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF5063 PF16702.5 AAL63070.1 - 0.024 15.0 3.2 1.4 9.3 0.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5063) MbeD_MobD PF04899.12 AAL63070.1 - 0.04 14.0 0.8 8.7 6.5 0.0 2.6 3 1 0 3 3 2 0 MbeD/MobD like Snapin_Pallidin PF14712.6 AAL63070.1 - 0.049 14.1 1.6 0.67 10.4 0.0 2.6 2 1 0 2 2 2 0 Snapin/Pallidin PLA2_B PF01735.18 AAL63070.1 - 0.073 11.5 0.0 0.085 11.2 0.0 1.1 1 0 0 1 1 1 0 Lysophospholipase catalytic domain Spc7 PF08317.11 AAL63070.1 - 0.08 11.8 9.8 0.37 9.6 9.8 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein CdvA PF18822.1 AAL63070.1 - 0.088 12.6 10.2 1.8 8.4 6.9 2.7 2 1 0 2 2 2 0 CdvA-like coiled-coil domain DUF948 PF06103.11 AAL63070.1 - 0.094 13.0 0.1 2.7 8.3 0.3 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 AAL63070.1 - 0.1 13.1 0.8 0.98 9.9 0.8 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein AKNA PF12443.8 AAL63070.1 - 0.11 13.2 0.6 1.3 9.7 0.1 2.3 2 0 0 2 2 2 0 AT-hook-containing transcription factor CENP-Q PF13094.6 AAL63070.1 - 0.13 12.4 7.6 0.25 11.6 1.6 2.0 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit CorA PF01544.18 AAL63070.1 - 0.18 11.1 2.4 0.2 10.9 0.9 1.7 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein ZapB PF06005.12 AAL63070.1 - 0.19 12.2 8.6 2.2 8.8 2.3 3.5 2 1 1 3 3 3 0 Cell division protein ZapB DUF2205 PF10224.9 AAL63070.1 - 0.2 11.7 8.0 0.61 10.1 0.2 2.9 3 1 0 3 3 3 0 Short coiled-coil protein XhlA PF10779.9 AAL63070.1 - 0.21 11.8 9.5 0.39 11.0 0.0 3.8 3 1 0 3 3 3 0 Haemolysin XhlA Transcrip_act PF04949.13 AAL63070.1 - 0.3 10.9 8.2 0.21 11.5 6.8 1.6 2 1 0 2 2 1 0 Transcriptional activator Spectrin PF00435.21 AAL63070.1 - 0.35 11.4 7.7 0.9 10.1 0.4 2.8 1 1 1 2 2 2 0 Spectrin repeat DUF1664 PF07889.12 AAL63070.1 - 0.45 10.6 4.7 0.99 9.4 1.4 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 AAL63070.1 - 0.48 10.6 2.7 1.3 9.2 1.2 2.4 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DivIC PF04977.15 AAL63070.1 - 0.62 9.9 9.7 1.9 8.3 1.5 3.1 2 1 1 3 3 3 0 Septum formation initiator BLOC1_2 PF10046.9 AAL63070.1 - 0.69 10.3 6.2 1.4 9.2 0.2 3.3 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Atg14 PF10186.9 AAL63070.1 - 0.75 8.8 4.0 0.98 8.4 4.0 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SlyX PF04102.12 AAL63070.1 - 0.86 10.3 4.8 1.2 9.8 0.1 3.1 3 2 1 4 4 4 0 SlyX BMFP PF04380.13 AAL63070.1 - 0.98 9.9 5.1 1.7 9.2 0.2 3.2 3 1 0 3 3 2 0 Membrane fusogenic activity DUF2203 PF09969.9 AAL63070.1 - 1.3 9.7 6.4 0.59 10.9 1.7 2.4 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF1690 PF07956.11 AAL63070.1 - 1.3 9.4 6.8 0.6 10.5 3.4 2.0 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) DUF4337 PF14235.6 AAL63070.1 - 2.9 8.0 8.6 0.93 9.6 1.9 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4337) TPR_MLP1_2 PF07926.12 AAL63070.1 - 3.1 7.9 10.9 3 7.9 0.6 2.8 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein YvrJ PF12841.7 AAL63070.1 - 3.4 7.3 5.4 19 4.9 0.3 3.4 3 0 0 3 3 3 0 YvrJ protein family DUF4315 PF14193.6 AAL63070.1 - 7.1 6.7 10.2 0.46 10.5 1.2 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4315) NfeD PF01957.18 AAL63071.1 - 1.9e-12 47.4 0.4 3.3e-12 46.6 0.4 1.3 1 0 0 1 1 1 1 NfeD-like C-terminal, partner-binding Phage_holin_3_6 PF07332.11 AAL63071.1 - 0.37 10.8 7.3 0.49 10.5 7.3 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III CLP1_P PF16575.5 AAL63072.1 - 1.2e-28 100.2 0.1 1.7e-27 96.4 0.0 2.0 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CbiA PF01656.23 AAL63072.1 - 0.0018 18.3 0.0 0.0022 18.1 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 AAL63072.1 - 0.06 13.6 0.0 0.12 12.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain MobB PF03205.14 AAL63072.1 - 0.11 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MipZ PF09140.11 AAL63072.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 ATPase MipZ MMR_HSR1 PF01926.23 AAL63072.1 - 0.11 12.5 0.0 0.4 10.8 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase PaREP1 PF05942.11 AAL63073.1 - 6.7e-26 90.5 0.0 7.9e-26 90.2 0.0 1.1 1 0 0 1 1 1 1 Archaeal PaREP1/PaREP8 family F420_oxidored PF03807.17 AAL63073.1 - 0.16 12.6 0.1 0.26 11.9 0.1 1.3 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent PaRep2a PF07903.11 AAL63074.1 - 4.1e-14 52.5 0.1 4.5e-14 52.3 0.1 1.0 1 0 0 1 1 1 1 PaRep2a protein PaRep2b PF07775.11 AAL63076.1 - 4.3e-135 451.1 10.5 5.6e-103 345.1 2.3 2.6 1 1 1 2 2 2 2 PaRep2b protein SesA PF17107.5 AAL63076.1 - 0.73 10.0 7.9 0.22 11.7 0.6 3.8 4 0 0 4 4 4 0 N-terminal domain on NACHT_NTPase and P-loop NTPases PaRep2b PF07775.11 AAL63077.1 - 1.1e-08 34.0 0.1 1.2e-08 33.9 0.1 1.0 1 0 0 1 1 1 1 PaRep2b protein DUF1653 PF07866.11 AAL63078.1 - 0.13 12.6 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1653) Fer4 PF00037.27 AAL63079.1 - 1.1e-06 28.2 10.7 0.00061 19.5 2.2 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 AAL63079.1 - 7.9e-06 25.7 14.8 0.00042 20.3 4.4 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 AAL63079.1 - 9e-06 25.8 8.0 1.8e-05 24.8 8.0 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAL63079.1 - 3.5e-05 23.6 12.8 0.0024 17.9 2.2 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 AAL63079.1 - 0.00079 20.0 9.7 0.2 12.3 1.9 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAL63079.1 - 0.0015 18.6 12.0 0.0049 16.9 12.0 1.9 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAL63079.1 - 0.025 15.1 7.0 1.7 9.3 0.4 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 AAL63079.1 - 0.4 10.9 10.1 0.98 9.6 10.1 1.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 AAL63079.1 - 1 10.1 9.3 9.2 7.1 0.6 2.4 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_3 PF12798.7 AAL63079.1 - 2.3 9.3 13.8 0.86 10.7 5.3 2.8 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_4 PF12800.7 AAL63079.1 - 3.4 8.4 11.5 0.35 11.5 1.9 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain MTHFR_C PF12225.8 AAL63079.1 - 5 6.8 10.2 4.2 7.1 0.5 2.3 1 1 1 2 2 2 0 Methylene-tetrahydrofolate reductase C terminal Fer4_8 PF13183.6 AAL63079.1 - 9.4 6.8 12.9 9e+02 0.4 12.6 2.4 1 1 0 1 1 1 0 4Fe-4S dicluster domain CxxCxxCC PF03692.15 AAL63080.1 - 8e-05 23.2 0.0 9.9e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Putative zinc- or iron-chelating domain DUF3109 PF11307.8 AAL63080.1 - 0.032 14.0 0.3 0.06 13.2 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3109) Ribosomal_L14e PF01929.17 AAL63081.1 - 5.8e-05 23.5 0.1 0.00013 22.4 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L14 GlcV_C_terminal PF17847.1 AAL63081.1 - 0.021 15.2 1.2 0.033 14.7 1.2 1.4 1 0 0 1 1 1 0 Glucose ABC transporter C-terminal domain KOW PF00467.29 AAL63081.1 - 0.6 10.1 10.5 0.081 12.9 6.1 1.9 2 0 0 2 2 2 0 KOW motif TruB_N PF01509.18 AAL63082.1 - 1.1e-24 87.6 0.1 3.7e-21 76.1 0.1 3.1 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 AAL63082.1 - 2.1e-22 79.0 0.0 4.5e-22 78.0 0.0 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 AAL63082.1 - 2.7e-20 72.1 0.0 6e-20 71.0 0.0 1.6 1 0 0 1 1 1 1 PUA domain DKCLD PF08068.12 AAL63082.1 - 3.1e-14 52.8 0.1 7e-14 51.6 0.1 1.6 1 0 0 1 1 1 1 DKCLD (NUC011) domain UPF0113 PF03657.13 AAL63082.1 - 0.013 15.8 0.0 0.066 13.5 0.0 2.2 3 0 0 3 3 3 0 UPF0113 PUA domain DUF211 PF02680.14 AAL63083.1 - 1.2e-29 102.3 7.5 1.3e-29 102.2 7.5 1.0 1 0 0 1 1 1 1 Uncharacterized ArCR, COG1888 VIT1 PF01988.19 AAL63084.1 - 0.0051 16.7 5.4 0.0051 16.7 5.4 2.4 1 1 1 2 2 2 2 VIT family DUF4245 PF14030.6 AAL63084.1 - 0.097 12.7 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4245) Gp_UL130 PF11668.8 AAL63085.1 - 0.14 12.0 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 HCMV glycoprotein pUL130 GFO_IDH_MocA PF01408.22 AAL63086.1 - 1.8e-17 64.3 0.1 2.5e-17 63.8 0.1 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 AAL63086.1 - 2.2e-05 24.5 0.0 6.7e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain AAA_16 PF13191.6 AAL63087.1 - 0.00015 22.2 0.0 0.00022 21.6 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 AAL63087.1 - 0.0002 21.1 0.0 0.00028 20.7 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 AAL63087.1 - 0.002 18.4 0.1 0.0047 17.2 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.6 AAL63087.1 - 0.003 17.3 0.0 0.0042 16.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 AAL63087.1 - 0.0034 17.0 0.0 0.0045 16.6 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 AAL63087.1 - 0.0035 16.4 0.0 0.0048 15.9 0.0 1.1 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54 PF00448.22 AAL63087.1 - 0.0056 16.3 0.0 0.0067 16.1 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA PF00004.29 AAL63087.1 - 0.0077 16.7 0.0 0.01 16.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 AAL63087.1 - 0.0079 15.6 0.0 0.0097 15.3 0.0 1.2 1 0 0 1 1 1 1 KaiC ATP_bind_1 PF03029.17 AAL63087.1 - 0.0084 15.9 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MobB PF03205.14 AAL63087.1 - 0.015 15.2 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATPase_2 PF01637.18 AAL63087.1 - 0.016 15.1 0.0 0.021 14.7 0.0 1.4 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 AAL63087.1 - 0.023 15.1 0.0 0.035 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 AAL63087.1 - 0.037 14.1 0.0 0.07 13.2 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain KTI12 PF08433.10 AAL63087.1 - 0.04 13.4 0.0 0.057 12.9 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 NACHT PF05729.12 AAL63087.1 - 0.041 13.8 0.0 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 AAL63087.1 - 0.045 13.3 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Ploopntkinase3 PF18751.1 AAL63087.1 - 0.048 13.6 0.0 0.058 13.3 0.0 1.2 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 ABC_tran PF00005.27 AAL63087.1 - 0.065 13.7 0.0 0.091 13.3 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Mg_chelatase PF01078.21 AAL63087.1 - 0.077 12.4 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 AAL63087.1 - 0.078 13.0 0.1 0.11 12.5 0.1 1.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 AAL63087.1 - 0.078 13.1 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AAL63087.1 - 0.088 12.5 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 AAL63087.1 - 0.09 12.5 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_32 PF13654.6 AAL63087.1 - 0.098 11.4 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 AAL63087.1 - 0.098 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 NTPase FtsK_SpoIIIE PF01580.18 AAL63087.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_18 PF13238.6 AAL63087.1 - 0.1 13.1 0.0 0.14 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 AAL63087.1 - 0.13 12.5 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 AAL63087.1 - 0.14 12.5 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase T2SSE PF00437.20 AAL63087.1 - 0.2 10.7 0.0 0.27 10.3 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_10 PF12846.7 AAL63087.1 - 0.24 10.3 0.1 0.31 9.9 0.1 1.2 1 0 0 1 1 1 0 AAA-like domain CPBP PF02517.16 AAL63088.1 - 7.3e-16 58.3 5.0 7.3e-16 58.3 5.0 2.0 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease YhfC PF10086.9 AAL63088.1 - 0.015 14.6 4.6 0.014 14.8 3.7 1.4 1 1 0 1 1 1 0 YhfC intramembrane metalloprotease Tricorn_C1 PF14684.6 AAL63089.1 - 0.15 12.2 0.2 0.94 9.6 0.0 2.1 2 0 0 2 2 2 0 Tricorn protease C1 domain MoCF_biosynth PF00994.24 AAL63090.1 - 1e-39 135.5 0.0 1.4e-39 135.0 0.0 1.2 1 0 0 1 1 1 1 Probable molybdopterin binding domain DpnD-PcfM PF14207.6 AAL63090.1 - 0.0013 18.5 0.3 0.18 11.7 0.0 2.4 2 0 0 2 2 2 2 DpnD/PcfM-like protein PNP_UDP_1 PF01048.20 AAL63090.1 - 0.0049 16.2 0.0 0.015 14.6 0.0 1.8 2 0 0 2 2 2 1 Phosphorylase superfamily EamA PF00892.20 AAL63091.1 - 1.1e-18 67.7 43.0 1.1e-10 41.8 9.8 3.0 3 0 0 3 3 3 2 EamA-like transporter family AhpC-TSA PF00578.21 AAL63092.1 - 1.1e-26 93.2 0.0 1.2e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AAL63092.1 - 1.9e-18 66.6 0.0 2.1e-18 66.4 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 AAL63092.1 - 5.8e-05 23.2 0.0 6.8e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme DUF899 PF05988.12 AAL63092.1 - 0.013 15.0 0.0 0.015 14.9 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) Thioredoxin_8 PF13905.6 AAL63092.1 - 0.014 15.7 0.0 0.019 15.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like DUF2551 PF10826.8 AAL63092.1 - 0.018 15.3 0.0 0.071 13.4 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2551) DUF4850 PF16142.5 AAL63092.1 - 0.12 11.9 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4850) TusA PF01206.17 AAL63093.1 - 6.5e-05 22.7 0.0 7.7e-05 22.4 0.0 1.0 1 0 0 1 1 1 1 Sulfurtransferase TusA DrsE_2 PF13686.6 AAL63094.1 - 1.1e-12 48.1 0.2 6.2e-06 26.2 0.1 2.0 1 1 1 2 2 2 2 DsrE/DsrF/DrsH-like family DrsE PF02635.15 AAL63094.1 - 9e-10 38.9 0.0 1.1e-09 38.7 0.0 1.1 1 0 0 1 1 1 1 DsrE/DsrF-like family HhH-GPD PF00730.25 AAL63095.1 - 2.9e-23 82.4 0.0 3.6e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 AAL63095.1 - 6.4e-06 25.8 0.1 2.1e-05 24.1 0.1 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 AAL63095.1 - 0.00028 21.4 0.1 0.0068 17.0 0.0 2.6 2 1 1 3 3 3 1 Helix-hairpin-helix domain EndIII_4Fe-2S PF10576.9 AAL63095.1 - 0.0011 19.2 6.7 0.002 18.4 6.7 1.5 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III HHH_8 PF14716.6 AAL63095.1 - 0.011 16.0 0.5 0.87 10.0 0.2 2.8 1 1 1 2 2 2 0 Helix-hairpin-helix domain IMS_HHH PF11798.8 AAL63095.1 - 0.019 15.3 0.1 0.27 11.6 0.0 2.7 2 0 0 2 2 2 0 IMS family HHH motif IF2_N PF04760.15 AAL63096.1 - 0.013 15.3 0.2 0.62 9.9 0.0 2.4 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region HTH_10 PF04967.12 AAL63096.1 - 0.035 13.9 0.1 5.1 7.0 0.0 3.0 3 0 0 3 3 3 0 HTH DNA binding domain AAA_16 PF13191.6 AAL63097.1 - 0.03 14.7 0.0 0.056 13.8 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 AAL63097.1 - 0.12 12.8 0.1 0.6 10.5 0.0 2.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Peptidase_M32 PF02074.15 AAL63098.1 - 1.5e-157 525.3 0.0 1.8e-157 525.1 0.0 1.0 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase Thg1 PF04446.12 AAL63099.1 - 2.9e-12 46.7 0.0 4.4e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase CTP_transf_like PF01467.26 AAL63100.1 - 1.5e-08 34.9 0.0 3.9e-08 33.6 0.0 1.7 1 1 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 AAL63100.1 - 0.025 14.4 0.0 0.048 13.6 0.0 1.5 2 0 0 2 2 2 0 FAD synthetase Peptidase_M28 PF04389.17 AAL63101.1 - 1.2e-06 28.4 0.0 1.4e-05 24.9 0.0 2.1 1 1 0 1 1 1 1 Peptidase family M28 PA PF02225.22 AAL63101.1 - 0.00052 20.0 0.4 0.0016 18.4 0.3 1.8 2 0 0 2 2 2 1 PA domain tRNA_bind_2 PF13725.6 AAL63102.1 - 0.00069 19.4 1.7 0.00078 19.2 1.7 1.1 1 0 0 1 1 1 1 Possible tRNA binding domain NPV_P10 PF05531.12 AAL63102.1 - 0.0071 16.8 9.0 0.039 14.4 3.8 2.8 1 1 2 3 3 3 1 Nucleopolyhedrovirus P10 protein MCPsignal PF00015.21 AAL63102.1 - 0.0093 15.8 1.3 0.011 15.5 1.3 1.1 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain DEAD PF00270.29 AAL63102.1 - 0.018 14.8 0.6 0.02 14.6 0.6 1.2 1 0 0 1 1 1 0 DEAD/DEAH box helicase Zea_mays_MuDR PF05928.11 AAL63102.1 - 0.036 13.7 0.3 0.039 13.6 0.3 1.1 1 0 0 1 1 1 0 Zea mays MURB-like protein (MuDR) DUF4795 PF16043.5 AAL63102.1 - 0.043 13.4 5.6 0.056 13.1 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) DUF4446 PF14584.6 AAL63102.1 - 0.047 13.7 1.7 0.054 13.5 1.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) Rep_1 PF01446.17 AAL63102.1 - 0.051 13.0 0.9 0.061 12.8 0.9 1.2 1 0 0 1 1 1 0 Replication protein Urocanase PF01175.18 AAL63102.1 - 0.055 13.1 0.5 0.08 12.6 0.5 1.3 1 1 0 1 1 1 0 Urocanase Rossmann-like domain Baculo_PEP_C PF04513.12 AAL63102.1 - 0.068 13.2 4.8 0.17 11.9 4.8 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Dad1 PF08649.10 AAL63102.1 - 0.076 13.2 0.5 7.4 6.9 0.0 2.6 2 0 0 2 2 2 0 DASH complex subunit Dad1 V-SNARE PF05008.15 AAL63102.1 - 0.12 12.8 5.3 1.5 9.2 0.3 3.0 2 1 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DUF2465 PF10239.9 AAL63102.1 - 0.12 11.5 3.9 0.13 11.4 3.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2465) DUF948 PF06103.11 AAL63102.1 - 0.17 12.2 4.0 2.5 8.4 2.1 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) TraF_2 PF13729.6 AAL63102.1 - 0.18 11.1 2.0 0.25 10.7 2.0 1.4 1 1 0 1 1 1 0 F plasmid transfer operon, TraF, protein YlbD_coat PF14071.6 AAL63102.1 - 0.27 11.5 3.1 0.43 10.8 2.5 1.7 1 1 1 2 2 2 0 Putative coat protein Turandot PF07240.11 AAL63102.1 - 0.34 10.9 2.0 0.34 10.9 0.6 1.8 2 0 0 2 2 2 0 Stress-inducible humoral factor Turandot DUF16 PF01519.16 AAL63102.1 - 0.49 10.9 6.2 2.1 8.9 5.5 1.9 1 1 1 2 2 2 0 Protein of unknown function DUF16 Acylphosphatase PF00708.18 AAL63103.1 - 1e-07 32.2 0.0 1.1e-07 32.1 0.0 1.0 1 0 0 1 1 1 1 Acylphosphatase BLUF PF04940.12 AAL63103.1 - 0.14 12.3 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Sensors of blue-light using FAD Hist_deacetyl PF00850.19 AAL63104.1 - 0.00012 21.6 0.0 0.00023 20.7 0.0 1.5 1 1 0 1 1 1 1 Histone deacetylase domain PDT PF00800.18 AAL63105.1 - 1.4e-33 116.2 0.0 1.9e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 AAL63105.1 - 6.3e-11 41.9 0.0 4.6e-10 39.1 0.0 2.4 2 1 0 2 2 2 1 ACT domain AsnC_trans_reg2 PF17805.1 AAL63105.1 - 0.098 12.8 0.0 0.27 11.4 0.0 1.8 1 0 0 1 1 1 0 AsnC-like ligand binding domain DEAD PF00270.29 AAL63106.1 - 3.5e-20 72.5 0.0 7.7e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase HHH_5 PF14520.6 AAL63106.1 - 4e-14 53.0 0.1 1.4e-13 51.3 0.1 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain Helicase_C PF00271.31 AAL63106.1 - 2.3e-09 37.6 0.0 2.5e-08 34.2 0.0 2.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain HHH_2 PF12826.7 AAL63106.1 - 9.4e-06 25.6 0.0 4.8e-05 23.4 0.0 2.3 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.23 AAL63106.1 - 2.2e-05 24.1 0.1 0.017 15.0 0.1 3.8 4 0 0 4 4 4 1 Helix-hairpin-helix motif ResIII PF04851.15 AAL63106.1 - 7.5e-05 22.8 0.0 0.00012 22.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DNA_pol_lambd_f PF10391.9 AAL63106.1 - 0.001 18.9 0.0 0.0031 17.3 0.0 1.8 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_3 PF12836.7 AAL63106.1 - 0.015 15.5 0.0 0.043 14.1 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif SNF2_N PF00176.23 AAL63106.1 - 0.023 13.4 0.0 0.036 12.8 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain HhH-GPD PF00730.25 AAL63106.1 - 0.08 13.4 0.0 0.24 11.9 0.0 1.8 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein IMS_HHH PF11798.8 AAL63106.1 - 0.14 12.6 0.0 18 5.9 0.0 2.9 2 0 0 2 2 2 0 IMS family HHH motif TilS_C PF11734.8 AAL63107.1 - 0.046 13.1 0.4 5 6.6 0.1 2.1 2 0 0 2 2 2 0 TilS substrate C-terminal domain MCM PF00493.23 AAL63108.1 - 7.3e-101 335.9 0.0 1e-100 335.5 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 AAL63108.1 - 4e-38 130.1 0.0 7.3e-38 129.3 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 AAL63108.1 - 1.5e-26 92.6 4.6 1.9e-26 92.3 2.7 2.1 2 0 0 2 2 2 1 MCM AAA-lid domain Mg_chelatase PF01078.21 AAL63108.1 - 1.9e-10 40.5 0.1 7.5e-07 28.7 0.0 2.5 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI MCM_N PF14551.6 AAL63108.1 - 2.2e-08 34.6 1.6 5e-08 33.5 0.1 2.4 3 0 0 3 3 2 1 MCM N-terminal domain AAA_5 PF07728.14 AAL63108.1 - 3.5e-07 30.3 0.0 1e-06 28.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 AAL63108.1 - 5.8e-07 29.4 0.0 1.6e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zn-ribbon_8 PF09723.10 AAL63108.1 - 5.1e-06 26.5 1.4 1.1e-05 25.5 1.4 1.4 1 0 0 1 1 1 1 Zinc ribbon domain Sigma54_activat PF00158.26 AAL63108.1 - 0.0014 18.3 0.1 0.0072 16.1 0.1 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.29 AAL63108.1 - 0.0019 18.6 0.0 0.0067 16.9 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AAL63108.1 - 0.0062 16.9 0.0 0.044 14.2 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain HypA PF01155.19 AAL63108.1 - 0.014 15.4 0.1 0.034 14.2 0.1 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA AAA_30 PF13604.6 AAL63108.1 - 0.018 14.8 1.2 0.046 13.4 1.2 1.6 1 0 0 1 1 1 0 AAA domain Zn_ribbon_SprT PF17283.2 AAL63108.1 - 0.16 11.9 2.2 0.49 10.4 2.3 1.8 1 1 0 1 1 1 0 SprT-like zinc ribbon domain zinc_ribbon_2 PF13240.6 AAL63108.1 - 0.64 9.8 4.6 8.9 6.2 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Rubredoxin_2 PF18073.1 AAL63108.1 - 1.2 8.9 5.4 4.3 7.1 1.0 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain PaREP1 PF05942.11 AAL63109.1 - 1.1e-27 96.2 1.8 1.6e-27 95.7 1.8 1.2 1 0 0 1 1 1 1 Archaeal PaREP1/PaREP8 family HEPN PF05168.14 AAL63111.1 - 3.4e-26 91.7 1.4 4.2e-26 91.4 1.4 1.0 1 0 0 1 1 1 1 HEPN domain NTP_transf_2 PF01909.23 AAL63112.1 - 1.8e-13 50.5 0.0 2.3e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 AAL63112.1 - 7.3e-08 32.4 0.0 9.2e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase DUF294 PF03445.13 AAL63112.1 - 0.046 13.5 0.0 0.087 12.6 0.0 1.6 1 1 0 1 1 1 0 Putative nucleotidyltransferase DUF294 DNA_pol_B_palm PF14792.6 AAL63112.1 - 0.057 13.6 0.0 0.061 13.5 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase beta palm SPOR PF05036.13 AAL63113.1 - 9.7e-05 22.7 0.7 0.00026 21.3 0.7 1.7 1 0 0 1 1 1 1 Sporulation related domain Arg_decarbox_C PF17944.1 AAL63113.1 - 2 9.0 5.6 23 5.7 0.1 4.4 5 0 0 5 5 5 0 Arginine decarboxylase C-terminal helical extension Exonuc_VII_L PF02601.15 AAL63113.1 - 3.1 7.3 18.4 0.87 9.1 8.2 2.4 2 1 1 3 3 3 0 Exonuclease VII, large subunit Tropomyosin PF00261.20 AAL63113.1 - 4.6 6.5 33.2 0.097 12.0 1.4 3.9 2 1 2 4 4 4 0 Tropomyosin DUF1697 PF08002.11 AAL63113.1 - 8.7 6.8 6.1 2.6 8.5 0.1 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF1697) Class_IIIsignal PF04021.12 AAL63116.1 - 0.0022 17.9 6.6 0.0048 16.8 6.6 1.6 1 0 0 1 1 1 1 Class III signal peptide PMT PF02366.18 AAL63117.1 - 2e-05 24.3 6.3 3.9e-05 23.3 6.3 1.4 1 1 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase SH3_6 PF12913.7 AAL63120.1 - 0.017 14.6 0.0 0.052 13.1 0.0 1.8 1 0 0 1 1 1 0 SH3 domain (SH3b1 type) WD40_like PF17005.5 AAL63120.1 - 0.087 12.1 0.0 0.28 10.5 0.0 1.8 2 0 0 2 2 2 0 WD40-like domain ATPase_2 PF01637.18 AAL63121.1 - 8.6e-24 84.7 0.0 2.5e-23 83.2 0.0 1.7 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 AAL63121.1 - 0.00032 21.1 0.0 0.00044 20.7 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AAL63121.1 - 0.0021 18.3 0.0 0.004 17.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain RecA PF00154.21 AAL63121.1 - 0.0026 17.2 0.0 0.009 15.5 0.0 1.7 1 1 0 1 1 1 1 recA bacterial DNA recombination protein AAA PF00004.29 AAL63121.1 - 0.0036 17.7 0.0 0.0071 16.8 0.0 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 AAL63121.1 - 0.013 15.2 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AAL63121.1 - 0.064 12.8 0.0 0.19 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 AAL63121.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TIP49 PF06068.13 AAL63121.1 - 0.17 11.0 0.2 14 4.8 0.0 2.1 2 0 0 2 2 2 0 TIP49 P-loop domain Aminotran_1_2 PF00155.21 AAL63123.1 - 9.2e-32 110.6 0.0 1.1e-31 110.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II HSBP1 PF06825.12 AAL63124.1 - 1.2e-06 28.2 23.3 0.016 15.1 3.7 5.1 1 1 4 5 5 5 3 Heat shock factor binding protein 1 DUF948 PF06103.11 AAL63124.1 - 7.3e-06 26.1 13.2 0.018 15.3 4.1 3.4 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF948) Apolipoprotein PF01442.18 AAL63124.1 - 1.6e-05 24.9 8.7 0.00011 22.1 8.6 1.9 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain ABC_tran_CTD PF16326.5 AAL63124.1 - 0.00018 21.7 8.2 0.079 13.2 1.3 2.9 1 1 1 2 2 2 2 ABC transporter C-terminal domain TPR_MLP1_2 PF07926.12 AAL63124.1 - 0.00048 20.2 9.5 0.0057 16.7 2.7 2.6 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein ApoLp-III PF07464.11 AAL63124.1 - 0.00054 20.1 10.2 0.0055 16.8 8.4 2.2 1 1 1 2 2 2 2 Apolipophorin-III precursor (apoLp-III) Exonuc_VII_L PF02601.15 AAL63124.1 - 0.00085 19.0 6.2 0.001 18.7 6.2 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit DUF1664 PF07889.12 AAL63124.1 - 0.0012 18.8 15.2 0.027 14.5 6.1 2.7 1 1 2 3 3 3 2 Protein of unknown function (DUF1664) T3SSipB PF16535.5 AAL63124.1 - 0.0013 19.3 3.4 0.079 13.4 0.2 2.5 1 1 1 2 2 2 1 Type III cell invasion protein SipB KxDL PF10241.9 AAL63124.1 - 0.0023 18.2 11.6 0.27 11.5 4.6 3.3 1 1 2 3 3 3 2 Uncharacterized conserved protein DUF16 PF01519.16 AAL63124.1 - 0.0029 18.1 18.4 0.039 14.5 4.9 2.7 1 1 1 2 2 2 1 Protein of unknown function DUF16 Fzo_mitofusin PF04799.13 AAL63124.1 - 0.0036 16.8 11.3 0.044 13.3 1.9 2.9 1 1 2 3 3 3 1 fzo-like conserved region EspB PF05802.11 AAL63124.1 - 0.0038 17.3 4.7 0.0053 16.8 4.3 1.4 1 1 0 1 1 1 1 Enterobacterial EspB protein DUF4407 PF14362.6 AAL63124.1 - 0.0046 16.4 7.6 0.012 15.0 7.6 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4407) Uds1 PF15456.6 AAL63124.1 - 0.006 16.8 10.6 0.006 16.7 6.6 2.2 1 1 1 2 2 2 1 Up-regulated During Septation Muted PF14942.6 AAL63124.1 - 0.0078 16.6 13.6 0.14 12.5 8.7 2.2 1 1 1 2 2 2 1 Organelle biogenesis, Muted-like protein Glyco_H_20C_C PF18088.1 AAL63124.1 - 0.0087 15.9 1.8 0.02 14.7 1.5 1.9 1 1 0 1 1 1 1 Glycoside Hydrolase 20C C-terminal domain FliD_C PF07195.12 AAL63124.1 - 0.0087 15.5 13.9 0.17 11.2 4.2 2.9 1 1 2 3 3 3 2 Flagellar hook-associated protein 2 C-terminus MSP1b PF03429.13 AAL63124.1 - 0.012 13.7 0.1 0.013 13.6 0.1 1.2 1 0 0 1 1 1 0 Major surface protein 1B CorA PF01544.18 AAL63124.1 - 0.013 14.8 13.4 0.017 14.5 12.5 1.7 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Myb_CC_LHEQLE PF14379.6 AAL63124.1 - 0.014 15.1 5.7 5.6 6.8 0.1 4.6 2 2 3 5 5 5 0 MYB-CC type transfactor, LHEQLE motif BLOC1_2 PF10046.9 AAL63124.1 - 0.014 15.6 14.1 0.092 13.1 6.3 2.7 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ArgJ PF01960.18 AAL63124.1 - 0.016 14.0 0.1 0.034 12.9 0.0 1.5 1 1 1 2 2 2 0 ArgJ family YkyA PF10368.9 AAL63124.1 - 0.017 14.8 13.3 0.073 12.7 5.1 2.6 1 1 0 2 2 2 0 Putative cell-wall binding lipoprotein CdvA PF18822.1 AAL63124.1 - 0.018 14.8 21.9 0.32 10.8 1.5 4.1 2 1 2 4 4 4 0 CdvA-like coiled-coil domain V-SNARE_C PF12352.8 AAL63124.1 - 0.019 15.3 15.8 8.1 6.8 0.0 5.5 1 1 3 5 5 5 0 Snare region anchored in the vesicle membrane C-terminus DUF3540 PF12059.8 AAL63124.1 - 0.024 14.5 2.5 1.1 9.0 0.3 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3540) Transcrip_act PF04949.13 AAL63124.1 - 0.026 14.4 14.8 0.66 9.8 3.4 3.0 1 1 2 3 3 3 0 Transcriptional activator HAP1_N PF04849.13 AAL63124.1 - 0.048 12.9 14.2 0.89 8.7 8.6 2.1 1 1 1 2 2 2 0 HAP1 N-terminal conserved region HMMR_N PF15905.5 AAL63124.1 - 0.068 12.6 17.0 0.81 9.1 3.5 1.8 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Snapin_Pallidin PF14712.6 AAL63124.1 - 0.078 13.4 18.8 0.61 10.5 6.2 3.4 1 1 3 4 4 4 0 Snapin/Pallidin MCPsignal PF00015.21 AAL63124.1 - 0.078 12.8 10.1 1.4 8.7 10.4 2.3 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF3496 PF12001.8 AAL63124.1 - 0.084 13.3 8.9 2.8 8.3 1.1 3.8 1 1 3 4 4 4 0 Domain of unknown function (DUF3496) Syntaphilin PF15290.6 AAL63124.1 - 0.088 12.5 10.8 0.11 12.1 10.8 1.1 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp HlyE PF06109.13 AAL63124.1 - 0.094 12.0 7.8 0.38 10.0 0.5 2.5 1 1 1 2 2 2 0 Haemolysin E (HlyE) HalX PF08663.10 AAL63124.1 - 0.1 12.9 5.7 3.6 8.0 0.1 3.5 2 1 1 3 3 3 0 HalX domain ALMT PF11744.8 AAL63124.1 - 0.1 11.4 5.8 0.047 12.5 2.8 1.7 1 1 1 2 2 2 0 Aluminium activated malate transporter Baculo_PEP_C PF04513.12 AAL63124.1 - 0.11 12.5 12.8 0.18 11.8 4.3 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SH3BP5 PF05276.14 AAL63124.1 - 0.11 12.2 7.5 0.1 12.4 0.7 2.3 1 1 1 2 2 2 0 SH3 domain-binding protein 5 (SH3BP5) AAT PF03417.16 AAL63124.1 - 0.12 12.1 1.7 0.26 10.9 1.7 1.7 1 1 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase DUF2203 PF09969.9 AAL63124.1 - 0.12 13.1 7.7 2.7 8.7 0.5 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) GCN5L1 PF06320.13 AAL63124.1 - 0.12 12.5 8.7 1.4 9.1 1.4 3.1 1 1 2 3 3 3 0 GCN5-like protein 1 (GCN5L1) COG2 PF06148.11 AAL63124.1 - 0.13 12.3 10.7 0.12 12.5 1.9 2.6 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 SOAR PF16533.5 AAL63124.1 - 0.13 12.2 11.3 1.5 8.8 1.5 3.3 1 1 2 3 3 3 0 STIM1 Orai1-activating region Cluap1 PF10234.9 AAL63124.1 - 0.15 11.5 12.1 0.89 8.9 2.4 2.3 1 1 1 2 2 2 0 Clusterin-associated protein-1 DUF1845 PF08900.11 AAL63124.1 - 0.15 11.7 6.6 1.8 8.3 0.4 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF1845) RasGAP_C PF03836.15 AAL63124.1 - 0.16 12.1 11.4 0.56 10.3 0.9 3.1 1 1 2 3 3 3 0 RasGAP C-terminus Rad50_zn_hook PF04423.14 AAL63124.1 - 0.17 11.8 7.7 1.2e+02 2.6 0.0 5.7 6 1 0 6 6 5 0 Rad50 zinc hook motif Nup54 PF13874.6 AAL63124.1 - 0.17 12.0 10.6 2.9 8.0 10.6 2.2 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 LMBR1 PF04791.16 AAL63124.1 - 0.18 10.7 6.7 0.21 10.4 6.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein NPV_P10 PF05531.12 AAL63124.1 - 0.18 12.3 14.9 0.86 10.1 4.4 3.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein HypA PF01155.19 AAL63124.1 - 0.19 11.7 1.0 3 7.9 0.7 2.8 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Mt_ATP-synt_D PF05873.12 AAL63124.1 - 0.21 11.4 8.6 4.1 7.2 0.9 2.9 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) TcpS PF17456.2 AAL63124.1 - 0.22 11.6 11.8 1.6 8.8 4.3 2.8 1 1 1 2 2 2 0 Toxin-coregulated pilus protein S Spc7 PF08317.11 AAL63124.1 - 0.24 10.2 14.8 0.39 9.6 3.5 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein ApoO PF09769.9 AAL63124.1 - 0.25 11.3 1.2 2.7 8.0 0.2 2.3 1 1 1 2 2 2 0 Apolipoprotein O Spc42p PF11544.8 AAL63124.1 - 0.29 11.2 13.6 0.32 11.0 6.1 3.1 1 1 2 3 3 3 0 Spindle pole body component Spc42p LUC7 PF03194.15 AAL63124.1 - 0.32 10.6 12.4 3.5 7.2 12.4 2.1 1 1 0 1 1 1 0 LUC7 N_terminus Oleosin PF01277.17 AAL63124.1 - 0.35 10.6 1.8 25 4.7 0.1 2.8 1 1 2 3 3 3 0 Oleosin DUF883 PF05957.13 AAL63124.1 - 0.36 11.5 4.3 3 8.5 0.2 2.9 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) TMPIT PF07851.13 AAL63124.1 - 0.39 9.9 9.9 5.9 6.0 9.7 2.0 1 1 0 1 1 1 0 TMPIT-like protein DUF1515 PF07439.11 AAL63124.1 - 0.54 10.3 12.0 0.16 12.0 1.3 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1515) DUF2935 PF11155.8 AAL63124.1 - 0.56 10.6 5.7 4 7.8 1.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) Prefoldin_2 PF01920.20 AAL63124.1 - 0.65 10.0 13.8 2.9 7.9 2.7 3.2 1 1 3 4 4 4 0 Prefoldin subunit MafB PF06255.13 AAL63124.1 - 0.7 9.3 2.3 23 4.3 0.1 2.7 1 1 2 3 3 3 0 Neisseria toxin MafB DUF745 PF05335.13 AAL63124.1 - 0.72 9.5 4.7 1.7 8.3 4.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF745) DUF4413 PF14372.6 AAL63124.1 - 0.81 10.1 5.4 11 6.4 0.3 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4413) ApoC-I PF04691.12 AAL63124.1 - 0.93 9.5 4.8 5.2 7.1 0.3 3.1 1 1 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) Erp_C PF06780.11 AAL63124.1 - 0.97 9.4 15.7 6.1 6.9 0.9 4.9 1 1 4 5 5 5 0 Erp protein C-terminus TMCO5 PF14992.6 AAL63124.1 - 0.98 8.9 17.2 4.9 6.6 7.8 2.5 1 1 0 2 2 2 0 TMCO5 family MutS_IV PF05190.18 AAL63124.1 - 1.1 9.7 8.4 10 6.5 1.4 3.1 2 2 0 2 2 2 0 MutS family domain IV V_ATPase_I PF01496.19 AAL63124.1 - 1.1 7.0 8.3 2.5 5.9 7.6 1.7 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Prominin PF05478.11 AAL63124.1 - 1.2 7.0 11.9 1.8 6.4 11.9 1.4 1 1 0 1 1 1 0 Prominin MerR-DNA-bind PF09278.11 AAL63124.1 - 1.2 9.7 12.3 11 6.7 0.1 4.6 1 1 3 4 4 3 0 MerR, DNA binding DASH_Dad4 PF08650.10 AAL63124.1 - 1.3 9.1 12.8 11 6.1 0.3 3.7 1 1 2 3 3 3 0 DASH complex subunit Dad4 DUF4351 PF14261.6 AAL63124.1 - 1.4 9.1 8.0 23 5.2 0.1 4.4 1 1 4 5 5 3 0 Domain of unknown function (DUF4351) Fib_alpha PF08702.10 AAL63124.1 - 1.4 9.1 18.2 4.1 7.6 9.2 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family LCIB_C_CA PF18599.1 AAL63124.1 - 1.8 7.8 7.9 2.6 7.3 1.9 2.2 1 1 1 2 2 2 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases CagE_TrbE_VirB PF03135.14 AAL63124.1 - 2.3 8.3 7.2 3.9 7.5 1.9 2.9 1 1 2 3 3 3 0 CagE, TrbE, VirB family, component of type IV transporter system Prefoldin PF02996.17 AAL63124.1 - 2.4 8.1 11.9 2.6e+02 1.5 0.2 3.3 1 1 1 2 2 2 0 Prefoldin subunit Allexi_40kDa PF05549.11 AAL63124.1 - 2.4 7.6 9.1 7.5 6.0 0.7 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein Cortex-I_coil PF09304.10 AAL63124.1 - 2.6 8.3 12.9 1.8 8.8 2.1 3.0 1 1 1 2 2 2 0 Cortexillin I, coiled coil ACCA PF03255.14 AAL63124.1 - 3 7.7 10.5 2 8.2 1.6 2.3 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Med21 PF11221.8 AAL63124.1 - 3.2 8.0 11.8 0.39 11.0 1.2 2.8 1 1 1 3 3 3 0 Subunit 21 of Mediator complex DUF5426 PF17473.2 AAL63124.1 - 3.2 8.0 7.0 7.9 6.8 0.4 2.6 1 1 2 3 3 3 0 Family of unknown function (DUF5426) YabA PF06156.13 AAL63124.1 - 3.7 8.2 13.1 0.9 10.2 5.1 2.9 1 1 2 3 3 3 0 Initiation control protein YabA Baculo_ME53 PF06061.11 AAL63124.1 - 6 6.0 9.2 13 4.9 2.1 2.3 1 1 1 2 2 2 0 Baculoviridae ME53 FAM76 PF16046.5 AAL63124.1 - 7.1 5.9 14.0 4.4 6.6 0.7 2.0 1 1 0 2 2 2 0 FAM76 protein TolA_bind_tri PF16331.5 AAL63124.1 - 8.6 6.5 12.8 7.9 6.6 3.2 3.0 2 1 0 2 2 2 0 TolA binding protein trimerisation Radical_SAM_C PF16199.5 AAL63125.1 - 1.2e-23 82.9 0.1 2.2e-23 82.1 0.1 1.4 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 AAL63125.1 - 3.6e-22 79.5 0.0 1.3e-21 77.7 0.0 1.9 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_10 PF13673.7 AAL63125.1 - 0.00051 20.0 0.0 0.00089 19.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAL63125.1 - 0.0042 17.3 0.0 0.0092 16.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF2204 PF09970.9 AAL63127.1 - 3.3e-05 23.6 0.0 0.00028 20.6 0.0 2.0 1 1 1 2 2 2 1 Nucleotidyl transferase of unknown function (DUF2204) NTP_transf_5 PF14907.6 AAL63127.1 - 0.011 15.3 0.0 2.6 7.6 0.0 2.9 1 1 1 2 2 2 0 Uncharacterised nucleotidyltransferase TrmB PF01978.19 AAL63128.1 - 7.2e-05 22.6 0.1 9.7e-05 22.2 0.1 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR PF01047.22 AAL63128.1 - 0.0018 18.2 0.0 0.0025 17.7 0.0 1.2 1 0 0 1 1 1 1 MarR family DUF4423 PF14394.6 AAL63128.1 - 0.0022 17.7 0.0 0.0025 17.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) MarR_2 PF12802.7 AAL63128.1 - 0.0053 16.6 0.8 0.008 16.1 0.8 1.2 1 0 0 1 1 1 1 MarR family FeoC PF09012.10 AAL63128.1 - 0.0096 16.0 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 1 FeoC like transcriptional regulator Rrf2 PF02082.20 AAL63128.1 - 0.014 15.7 0.1 0.014 15.7 0.1 1.4 2 0 0 2 2 2 0 Transcriptional regulator HTH_27 PF13463.6 AAL63128.1 - 0.018 15.5 0.1 0.026 15.0 0.1 1.2 1 0 0 1 1 1 0 Winged helix DNA-binding domain DUF4381 PF14316.6 AAL63128.1 - 0.019 15.2 0.8 0.021 15.1 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF2250 PF10007.9 AAL63128.1 - 0.032 14.4 0.0 0.039 14.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) PaaX PF07848.12 AAL63128.1 - 0.04 14.1 0.2 0.054 13.7 0.2 1.3 1 0 0 1 1 1 0 PaaX-like protein DprA_WH PF17782.1 AAL63128.1 - 0.051 13.7 1.3 0.064 13.4 1.3 1.2 1 0 0 1 1 1 0 DprA winged helix domain HTH_47 PF16221.5 AAL63128.1 - 0.055 13.0 0.0 0.07 12.7 0.0 1.2 1 0 0 1 1 1 0 winged helix-turn-helix BLACT_WH PF17778.1 AAL63128.1 - 0.061 13.3 0.1 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 Beta-lactamase associated winged helix domain Methyltransf_11 PF08241.12 AAL63129.1 - 1e-09 38.9 0.0 2.4e-09 37.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAL63129.1 - 2.1e-07 31.6 0.0 7.9e-06 26.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAL63129.1 - 0.00012 22.0 0.0 0.00014 21.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAL63129.1 - 0.018 15.7 0.0 0.14 13.0 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain TatC PF00902.18 AAL63131.1 - 0.043 13.6 0.4 0.049 13.4 0.4 1.3 1 0 0 1 1 1 0 Sec-independent protein translocase protein (TatC) DUF5336 PF17270.2 AAL63131.1 - 0.34 10.5 3.9 1.5 8.4 1.9 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5336) OmpA_membrane PF01389.17 AAL63133.1 - 0.25 11.0 0.0 0.29 10.9 0.0 1.1 1 0 0 1 1 1 0 OmpA-like transmembrane domain UPF0051 PF01458.17 AAL63135.1 - 1.2e-21 77.4 0.3 1.7e-21 76.9 0.3 1.2 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) DUF1743 PF08489.11 AAL63136.1 - 4e-27 94.6 0.0 1.3e-26 93.0 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1743) Zn-ribbon_8 PF09723.10 AAL63136.1 - 0.03 14.5 0.5 3.6 7.8 0.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain C1_1 PF00130.22 AAL63136.1 - 0.032 14.1 1.7 0.054 13.4 0.7 1.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) OrfB_Zn_ribbon PF07282.11 AAL63136.1 - 0.049 13.6 3.8 0.099 12.6 3.8 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Zn_Tnp_IS1595 PF12760.7 AAL63136.1 - 0.081 12.9 2.9 0.2 11.7 2.9 1.7 1 0 0 1 1 1 0 Transposase zinc-ribbon domain HypA PF01155.19 AAL63136.1 - 0.15 12.1 0.1 0.4 10.7 0.1 1.6 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 AAL63136.1 - 0.21 11.6 1.8 0.19 11.8 0.3 1.5 2 0 0 2 2 2 0 Double zinc ribbon zf_Rg PF17915.1 AAL63136.1 - 0.39 10.2 2.0 0.86 9.1 2.0 1.5 1 0 0 1 1 1 0 Reverse gyrase zinc finger zf-ribbon_3 PF13248.6 AAL63136.1 - 0.59 9.6 3.2 7.1 6.2 3.2 2.2 1 1 0 1 1 1 0 zinc-ribbon domain Peripla_BP_2 PF01497.18 AAL63137.1 - 0.00018 21.1 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein DUF348 PF03990.14 AAL63137.1 - 0.044 13.5 0.0 0.77 9.6 0.0 2.4 2 0 0 2 2 2 0 G5-linked-Ubiquitin-like domain TauE PF01925.19 AAL63138.1 - 0.014 15.1 7.8 0.018 14.7 7.8 1.2 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE Neurensin PF14927.6 AAL63138.1 - 0.021 14.5 0.6 0.026 14.3 0.6 1.2 1 0 0 1 1 1 0 Neurensin PrgI PF12666.7 AAL63138.1 - 1.7 9.4 6.9 1.6 9.5 6.0 1.3 1 1 0 1 1 1 0 PrgI family protein ATPase_gene1 PF09527.10 AAL63138.1 - 3.2 8.0 17.2 1.2 9.3 3.1 3.1 2 1 1 3 3 3 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter CxxCxxCC PF03692.15 AAL63139.1 - 0.0014 19.3 0.0 0.0029 18.3 0.0 1.6 1 1 1 2 2 2 1 Putative zinc- or iron-chelating domain TPP_enzyme_C PF02775.21 AAL63140.1 - 1e-27 96.8 0.0 2.1e-27 95.8 0.0 1.5 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PFO_beta_C PF12367.8 AAL63140.1 - 4.3e-21 74.8 0.8 6.9e-21 74.2 0.8 1.3 1 0 0 1 1 1 1 Pyruvate ferredoxin oxidoreductase beta subunit C terminal POR_N PF01855.19 AAL63141.1 - 2.5e-49 168.1 0.0 4.1e-49 167.4 0.0 1.3 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.18 AAL63141.1 - 1e-36 126.7 0.1 2.8e-36 125.2 0.1 1.7 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 AAL63141.1 - 1.9e-06 28.1 0.0 1.6e-05 25.1 0.0 2.6 2 0 0 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II OxoGdeHyase_C PF16870.5 AAL63141.1 - 0.012 15.3 0.0 1.5 8.5 0.0 2.6 2 0 0 2 2 2 0 2-oxoglutarate dehydrogenase C-terminal TPP_enzyme_N PF02776.18 AAL63141.1 - 0.083 12.5 0.4 0.2 11.2 0.3 1.6 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain UvrC_HhH_N PF08459.11 AAL63141.1 - 0.17 11.8 0.0 0.73 9.7 0.0 1.9 2 0 0 2 2 2 0 UvrC Helix-hairpin-helix N-terminal MarC PF01914.17 AAL63143.1 - 6.8e-15 55.0 6.9 8.1e-15 54.8 6.9 1.1 1 0 0 1 1 1 1 MarC family integral membrane protein MarC PF01914.17 AAL63144.1 - 6.2e-11 42.1 2.6 7.1e-11 41.9 2.6 1.0 1 0 0 1 1 1 1 MarC family integral membrane protein SecE PF00584.20 AAL63144.1 - 1.3 9.0 7.6 3.9 7.5 7.6 1.9 1 1 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex FBPase_3 PF01950.16 AAL63145.1 - 1.6e-178 593.5 0.0 1.9e-178 593.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-1,6-bisphosphatase Acetyltransf_3 PF13302.7 AAL63146.1 - 1e-06 29.5 0.0 1.1e-06 29.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAL63146.1 - 7.7e-06 26.1 0.1 9.6e-06 25.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAL63146.1 - 0.00033 21.0 0.4 0.0011 19.3 0.1 2.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAL63146.1 - 0.00091 19.2 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein GNAT_acetyltran PF12746.7 AAL63146.1 - 0.086 12.4 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase CPSase_sm_chain PF00988.22 AAL63147.1 - 1.6e-45 154.1 0.0 2.3e-45 153.6 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 AAL63147.1 - 1.1e-40 139.5 0.0 1.4e-40 139.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AAL63147.1 - 5.6e-12 45.9 0.2 7.8e-10 38.9 0.2 2.2 1 1 0 1 1 1 1 Peptidase C26 CPSase_L_D2 PF02786.17 AAL63148.1 - 9.1e-95 316.1 0.0 1.1e-62 211.3 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 AAL63148.1 - 2.4e-25 89.2 0.0 5.6e-25 88.0 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 AAL63148.1 - 8.1e-16 58.1 0.1 1.4e-07 31.2 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 AAL63148.1 - 1.9e-11 43.9 0.0 7.3e-05 22.5 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.13 AAL63148.1 - 2.8e-11 43.4 0.1 7.5e-05 22.3 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp_5 PF13549.6 AAL63148.1 - 1.3e-10 41.1 0.0 0.00014 21.4 0.0 2.9 2 1 0 2 2 2 2 ATP-grasp domain RimK PF08443.11 AAL63148.1 - 3.7e-06 26.7 0.0 0.072 12.7 0.0 2.8 3 0 0 3 3 3 2 RimK-like ATP-grasp domain ATP-grasp_2 PF08442.10 AAL63148.1 - 0.0058 16.2 0.0 0.051 13.1 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain Exonuc_VII_S PF02609.16 AAL63148.1 - 0.12 12.5 1.8 0.92 9.6 0.0 3.2 3 0 0 3 3 3 0 Exonuclease VII small subunit RimK PF08443.11 AAL63149.1 - 8.7e-33 113.5 0.0 1.4e-32 112.8 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain GSH-S_ATP PF02955.16 AAL63149.1 - 1.3e-09 37.7 0.0 2.1e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATP-grasp_3 PF02655.14 AAL63149.1 - 2.3e-08 34.2 0.0 3.8e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 AAL63149.1 - 0.02 14.5 0.1 0.085 12.4 0.1 1.9 1 1 0 1 1 1 0 D-ala D-ala ligase C-terminus AIRS_C PF02769.22 AAL63150.1 - 8.6e-25 87.7 0.9 8.6e-25 87.7 0.9 1.6 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 AAL63150.1 - 4.7e-15 56.0 2.0 2.2e-14 53.8 0.3 2.5 2 1 0 2 2 2 1 AIR synthase related protein, N-terminal domain DUF2007 PF09413.10 AAL63150.1 - 0.072 13.3 0.1 1.7 8.9 0.1 2.5 2 0 0 2 2 2 0 Putative prokaryotic signal transducing protein Aminotran_1_2 PF00155.21 AAL63151.1 - 0.0014 17.9 0.0 1.8 7.7 0.0 2.6 1 1 1 2 2 2 2 Aminotransferase class I and II DUF63 PF01889.17 AAL63151.1 - 0.028 14.6 0.3 0.041 14.1 0.3 1.2 1 0 0 1 1 1 0 Membrane protein of unknown function DUF63 DUF4374 PF14298.6 AAL63151.1 - 0.099 11.4 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4374) DUF99 PF01949.16 AAL63152.1 - 5.2e-50 169.4 0.0 5.8e-50 169.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF99 HEAT_2 PF13646.6 AAL63152.1 - 0.034 14.5 0.1 8.9 6.8 0.1 2.3 2 0 0 2 2 2 0 HEAT repeats SBP_bac_8 PF13416.6 AAL63153.1 - 4.6e-25 89.0 0.1 5.5e-25 88.7 0.1 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AAL63153.1 - 5.4e-17 62.0 0.9 7.6e-17 61.5 0.9 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AAL63153.1 - 1e-15 58.5 3.2 1.5e-15 58.0 3.2 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 AAL63153.1 - 3.4e-06 27.0 0.0 7.7e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein PaRep2b PF07775.11 AAL63154.1 - 9.1e-271 898.7 13.7 1e-270 898.5 13.7 1.0 1 0 0 1 1 1 1 PaRep2b protein TrwB_AAD_bind PF10412.9 AAL63154.1 - 0.023 13.6 0.1 0.037 13.0 0.1 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain GA-like PF17573.2 AAL63154.1 - 6.4 6.8 7.9 24 4.9 1.0 3.4 3 0 0 3 3 3 0 GA-like domain PaRep2a PF07903.11 AAL63155.1 - 4.1e-13 49.2 0.8 4.1e-13 49.2 0.8 1.0 1 0 0 1 1 1 1 PaRep2a protein GATase PF00117.28 AAL63156.1 - 1.1e-14 54.6 0.0 1.3e-14 54.4 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 AAL63156.1 - 2.2e-05 24.4 0.0 6.8e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 AAL63156.1 - 0.00019 21.1 0.0 0.00022 20.9 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 AAL63156.1 - 0.0005 19.9 2.4 0.33 10.7 0.6 3.0 2 1 0 2 2 2 2 Peptidase C26 PRA-CH PF01502.18 AAL63157.1 - 2.3e-29 101.0 0.1 3.2e-29 100.6 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase Aminotran_1_2 PF00155.21 AAL63158.1 - 2e-30 106.2 0.0 2.4e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 AAL63158.1 - 0.1 11.4 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Allinase PaREP1 PF05942.11 AAL63159.1 - 5.9e-05 23.0 0.6 6.2e-05 22.9 0.6 1.0 1 0 0 1 1 1 1 Archaeal PaREP1/PaREP8 family HisG PF01634.18 AAL63160.1 - 1.7e-46 158.1 0.0 2.3e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 AAL63160.1 - 3.3e-22 78.4 0.2 8.5e-22 77.1 0.2 1.7 1 0 0 1 1 1 1 HisG, C-terminal domain FAP PF07174.11 AAL63160.1 - 0.09 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Thymidylate_kin PF02223.17 AAL63161.1 - 2.4e-47 161.0 0.0 2.8e-47 160.8 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase dNK PF01712.19 AAL63161.1 - 2.5e-08 34.1 0.2 1.7e-05 24.8 0.2 2.9 1 1 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.6 AAL63161.1 - 1.2e-06 29.1 0.0 4e-06 27.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 AAL63161.1 - 4e-05 23.9 0.0 5.4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AAL63161.1 - 0.0028 17.8 0.0 0.041 14.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain Ploopntkinase1 PF18748.1 AAL63161.1 - 0.0041 16.7 0.0 1.1 8.7 0.0 2.1 2 0 0 2 2 2 2 P-loop Nucleotide Kinase1 Ribosomal_L2 PF00181.23 AAL63161.1 - 0.067 13.2 0.1 17 5.4 0.0 2.4 1 1 1 2 2 2 0 Ribosomal Proteins L2, RNA binding domain AAA_22 PF13401.6 AAL63161.1 - 0.072 13.4 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 AAL63161.1 - 0.11 12.9 0.0 0.4 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AAL63161.1 - 0.2 12.2 0.1 0.33 11.5 0.1 1.4 1 1 0 1 1 1 0 ABC transporter Sld5 PF05916.11 AAL63162.1 - 3.3e-10 40.4 0.0 4e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein CPBP PF02517.16 AAL63163.1 - 5.1e-14 52.4 8.7 5.1e-14 52.4 8.7 2.5 1 1 1 2 2 2 1 CPBP intramembrane metalloprotease DUF4112 PF13430.6 AAL63163.1 - 0.17 12.2 1.9 8.7 6.7 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4112) LDcluster4 PF18306.1 AAL63164.1 - 8.2e-19 67.7 0.0 1e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 SLOG cluster4 family Lysine_decarbox PF03641.14 AAL63164.1 - 3.8e-05 23.8 0.1 7.3e-05 22.9 0.0 1.6 1 1 1 2 2 2 1 Possible lysine decarboxylase LSDAT_prok PF18171.1 AAL63164.1 - 0.0012 18.2 0.0 0.27 10.4 0.0 2.1 2 0 0 2 2 2 2 SLOG in TRPM, prokaryote Nuc_deoxyrib_tr PF05014.15 AAL63164.1 - 0.0025 17.8 0.1 0.0038 17.2 0.1 1.4 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase Cutinase PF01083.22 AAL63164.1 - 0.021 14.8 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 Cutinase MoCF_biosynth PF00994.24 AAL63165.1 - 2.5e-33 114.8 0.1 2.9e-33 114.6 0.1 1.0 1 0 0 1 1 1 1 Probable molybdopterin binding domain SCP2 PF02036.17 AAL63166.1 - 0.0021 18.5 0.0 0.0023 18.4 0.0 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Acid_PPase PF12689.7 AAL63167.1 - 1.2e-09 38.3 0.0 1.4e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase NIF PF03031.18 AAL63167.1 - 0.00011 22.0 0.1 0.00012 21.9 0.1 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.6 AAL63167.1 - 0.0019 18.3 0.0 0.016 15.3 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Lyase_1 PF00206.20 AAL63168.1 - 6.6e-32 111.1 0.0 1.6e-31 109.9 0.0 1.7 2 1 0 2 2 2 1 Lyase ASL_C PF08328.11 AAL63168.1 - 0.0026 17.9 0.1 0.0073 16.4 0.1 1.8 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminal HD_assoc PF13286.6 AAL63168.1 - 0.13 12.9 0.8 0.57 10.7 0.1 2.3 2 0 0 2 2 2 0 Phosphohydrolase-associated domain PaREP1 PF05942.11 AAL63169.1 - 2.3e-27 95.2 0.1 2.8e-27 94.9 0.1 1.1 1 0 0 1 1 1 1 Archaeal PaREP1/PaREP8 family Adenylsucc_synt PF00709.21 AAL63170.1 - 2.5e-69 234.2 0.0 6.1e-37 127.5 0.0 3.0 1 1 2 3 3 3 3 Adenylosuccinate synthetase UPF0175 PF03683.13 AAL63171.1 - 2.3e-09 36.8 0.0 3.6e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0175) PaREP1 PF05942.11 AAL63174.1 - 2.3e-23 82.3 2.3 2.8e-23 82.0 2.3 1.1 1 0 0 1 1 1 1 Archaeal PaREP1/PaREP8 family Pyr_redox_2 PF07992.14 AAL63175.1 - 3.3e-14 52.8 1.3 1.9e-07 30.6 0.1 3.1 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AAL63175.1 - 2.1e-10 39.9 1.7 3.3e-05 22.8 0.4 2.5 3 0 0 3 3 3 2 HI0933-like protein DAO PF01266.24 AAL63175.1 - 2.4e-09 37.2 7.4 4e-05 23.4 1.0 2.9 2 1 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.22 AAL63175.1 - 5.2e-09 35.7 0.9 0.0016 17.6 0.0 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 AAL63175.1 - 9.2e-09 35.0 1.1 0.0036 16.6 0.4 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 AAL63175.1 - 1.3e-06 27.9 0.1 2.3e-06 27.0 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 AAL63175.1 - 1.6e-06 27.5 1.2 1.6e-06 27.5 1.2 2.9 3 0 0 3 3 3 1 FAD binding domain FAD_binding_3 PF01494.19 AAL63175.1 - 3.5e-05 23.2 0.5 5.5e-05 22.6 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 AAL63175.1 - 0.00032 19.8 1.3 0.00041 19.5 0.5 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 AAL63175.1 - 0.002 18.3 3.2 0.0033 17.6 0.8 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 AAL63175.1 - 0.0044 17.0 0.9 0.32 11.0 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 AAL63175.1 - 0.0063 15.9 3.2 0.079 12.3 2.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 AAL63175.1 - 0.0085 16.6 2.3 2 9.0 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EVE PF01878.18 AAL63175.1 - 0.032 14.3 0.0 8.8 6.3 0.0 2.2 1 1 1 2 2 2 0 EVE domain ThiF PF00899.21 AAL63175.1 - 0.1 11.9 0.2 0.19 11.1 0.2 1.4 1 0 0 1 1 1 0 ThiF family Trp_halogenase PF04820.14 AAL63175.1 - 0.22 10.3 1.1 0.32 9.8 1.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Amino_oxidase PF01593.24 AAL63175.1 - 0.31 10.3 4.7 8.7 5.5 0.0 3.0 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase DUF202 PF02656.15 AAL63176.1 - 1.9 9.0 0.0 1.9 9.0 0.0 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF202) PRA-PH PF01503.17 AAL63178.1 - 5.4e-17 62.0 0.1 6e-17 61.9 0.1 1.0 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 AAL63178.1 - 1.6e-05 25.0 0.3 2.1e-05 24.6 0.3 1.2 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain MazG-like PF12643.7 AAL63178.1 - 0.046 14.0 0.2 0.085 13.1 0.1 1.5 2 0 0 2 2 2 0 MazG-like family Histidinol_dh PF00815.20 AAL63179.1 - 1.7e-68 231.5 0.0 3.1e-68 230.7 0.0 1.3 1 1 0 1 1 1 1 Histidinol dehydrogenase Rho_N PF07498.12 AAL63179.1 - 0.15 12.0 2.1 3.8 7.5 0.3 2.4 2 0 0 2 2 2 0 Rho termination factor, N-terminal domain His_biosynth PF00977.21 AAL63180.1 - 7.2e-86 287.4 2.1 8.2e-86 287.2 2.1 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Dus PF01207.17 AAL63180.1 - 3.1e-10 39.6 0.1 1e-06 28.1 0.0 2.1 1 1 1 2 2 2 2 Dihydrouridine synthase (Dus) ThiG PF05690.14 AAL63180.1 - 8.8e-10 38.3 1.7 0.00047 19.5 0.2 2.2 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG NMO PF03060.15 AAL63180.1 - 1.9e-09 37.4 6.6 0.00015 21.3 0.8 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase DHO_dh PF01180.21 AAL63180.1 - 2.1e-09 37.0 0.0 0.00069 18.9 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase IMPDH PF00478.25 AAL63180.1 - 1.4e-07 30.9 2.0 0.0011 18.0 0.1 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain TMP-TENI PF02581.17 AAL63180.1 - 4.5e-07 29.4 1.0 0.014 14.7 0.1 2.3 2 0 0 2 2 2 2 Thiamine monophosphate synthase G3P_antiterm PF04309.12 AAL63180.1 - 8e-07 28.6 0.2 0.013 14.9 0.0 2.2 2 0 0 2 2 2 2 Glycerol-3-phosphate responsive antiterminator FMN_dh PF01070.18 AAL63180.1 - 7.4e-05 21.9 3.4 0.088 11.8 0.3 2.2 2 0 0 2 2 2 2 FMN-dependent dehydrogenase BtpA PF03437.15 AAL63180.1 - 0.0019 17.7 0.6 0.076 12.4 0.1 2.2 2 0 0 2 2 2 1 BtpA family PcrB PF01884.17 AAL63180.1 - 0.0021 17.5 0.3 0.037 13.5 0.1 2.1 2 0 0 2 2 2 1 PcrB family SOR_SNZ PF01680.17 AAL63180.1 - 0.0045 16.8 0.2 0.24 11.2 0.0 2.4 2 0 0 2 2 2 1 SOR/SNZ family Trp_syntA PF00290.20 AAL63180.1 - 0.0046 15.8 0.6 0.046 12.6 0.1 2.0 2 0 0 2 2 2 1 Tryptophan synthase alpha chain IGPS PF00218.21 AAL63180.1 - 0.0057 15.9 0.0 0.19 10.9 0.0 2.3 2 1 0 2 2 2 1 Indole-3-glycerol phosphate synthase DUF561 PF04481.12 AAL63180.1 - 0.017 14.3 0.0 3 6.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF561) PE PF00934.20 AAL63180.1 - 0.29 11.5 3.1 0.47 10.8 0.3 2.3 2 0 0 2 2 2 0 PE family IGPD PF00475.18 AAL63181.1 - 6.8e-44 149.7 0.1 8.3e-44 149.4 0.1 1.1 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase His_biosynth PF00977.21 AAL63182.1 - 3.2e-49 167.5 0.1 3.6e-49 167.3 0.1 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein FMN_dh PF01070.18 AAL63182.1 - 0.0043 16.1 1.5 0.0063 15.6 1.0 1.4 1 1 0 1 1 1 1 FMN-dependent dehydrogenase PcrB PF01884.17 AAL63182.1 - 0.0069 15.9 0.5 0.21 11.0 0.3 2.2 2 0 0 2 2 2 1 PcrB family ThiG PF05690.14 AAL63182.1 - 0.13 11.5 0.1 0.19 11.0 0.1 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG Dus PF01207.17 AAL63182.1 - 0.21 10.7 0.1 0.29 10.2 0.1 1.1 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) gag-asp_proteas PF13975.6 AAL63184.1 - 6.5e-09 36.2 0.0 9.2e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 AAL63184.1 - 5.4e-07 30.2 0.0 7.8e-07 29.7 0.0 1.4 1 1 0 1 1 1 1 Aspartyl protease RVP PF00077.20 AAL63184.1 - 0.0054 17.0 0.1 0.017 15.4 0.1 1.8 1 1 0 1 1 1 1 Retroviral aspartyl protease RtcB PF01139.17 AAL63187.1 - 5.5e-162 539.7 0.0 6.3e-162 539.5 0.0 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB Virulence_fact PF13769.6 AAL63187.1 - 0.084 13.1 0.1 0.28 11.4 0.1 1.9 1 0 0 1 1 1 0 Virulence factor Wzz PF02706.15 AAL63190.1 - 0.48 10.8 3.6 0.74 10.2 3.6 1.3 1 0 0 1 1 1 0 Chain length determinant protein Peptidase_S9 PF00326.21 AAL63191.1 - 5.5e-51 173.0 0.0 7.7e-51 172.6 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 AAL63191.1 - 3.4e-16 58.7 2.0 9.2e-07 28.6 0.0 4.1 4 0 0 4 4 4 3 WD40-like Beta Propeller Repeat Peptidase_S15 PF02129.18 AAL63191.1 - 2.2e-10 40.6 0.0 3.1e-08 33.5 0.1 2.2 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 AAL63191.1 - 1.3e-06 28.3 0.1 3e-06 27.1 0.1 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold AXE1 PF05448.12 AAL63191.1 - 0.00057 18.7 0.0 0.12 11.1 0.0 2.6 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) DPPIV_N PF00930.21 AAL63191.1 - 0.00074 18.4 0.0 0.036 12.8 0.0 3.0 2 1 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Hydrolase_4 PF12146.8 AAL63191.1 - 0.00082 18.7 0.1 0.89 8.8 0.1 2.5 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Gmad1 PF10647.9 AAL63191.1 - 0.0025 17.6 0.0 0.085 12.6 0.0 2.5 1 1 2 3 3 3 1 Lipoprotein LpqB beta-propeller domain DUF2920 PF11144.8 AAL63191.1 - 0.014 14.6 0.0 0.41 9.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) Abhydrolase_3 PF07859.13 AAL63191.1 - 0.095 12.5 0.0 2.2 8.1 0.0 2.3 1 1 0 1 1 1 0 alpha/beta hydrolase fold WD40 PF00400.32 AAL63191.1 - 0.13 13.2 0.4 1.1 10.3 0.2 2.8 3 0 0 3 3 2 0 WD domain, G-beta repeat DLH PF01738.18 AAL63191.1 - 0.22 11.1 0.0 0.48 9.9 0.0 1.5 1 1 0 1 1 1 0 Dienelactone hydrolase family Asparaginase PF00710.20 AAL63192.1 - 1.4e-53 181.3 0.2 2.5e-53 180.5 0.2 1.4 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 AAL63192.1 - 2.6e-28 98.5 0.2 2.1e-27 95.6 0.1 2.2 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain GatD_N PF18195.1 AAL63192.1 - 1.1e-14 53.5 0.5 2e-14 52.6 0.5 1.5 1 0 0 1 1 1 1 GatD N-terminal domain DUF2064 PF09837.9 AAL63192.1 - 0.017 14.9 0.0 0.039 13.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2064) HD_3 PF13023.6 AAL63193.1 - 2e-08 34.4 0.0 3.1e-08 33.7 0.0 1.5 1 1 0 1 1 1 1 HD domain HD_2 PF12917.7 AAL63193.1 - 2.1e-06 27.6 1.0 1e-05 25.4 1.0 1.9 1 1 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 AAL63193.1 - 2.3e-05 24.6 1.2 5.7e-05 23.3 1.2 1.7 1 1 0 1 1 1 1 HD domain zf-ZPR1 PF03367.13 AAL63194.1 - 1.1e-27 96.8 0.0 1.3e-27 96.6 0.0 1.0 1 0 0 1 1 1 1 ZPR1 zinc-finger domain Prim_Zn_Ribbon PF08273.12 AAL63194.1 - 0.00048 20.3 1.0 0.00088 19.5 1.0 1.4 1 0 0 1 1 1 1 Zinc-binding domain of primase-helicase zf-ribbon_3 PF13248.6 AAL63194.1 - 0.0043 16.4 1.3 0.92 9.0 0.1 2.3 2 0 0 2 2 2 2 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 AAL63194.1 - 0.065 13.2 0.9 0.7 9.9 1.2 2.1 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_2 PF13240.6 AAL63194.1 - 0.069 12.9 4.7 3.9 7.3 0.5 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DNA_ligase_ZBD PF03119.16 AAL63194.1 - 0.07 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain DZR PF12773.7 AAL63194.1 - 0.087 12.9 0.0 0.17 11.9 0.0 1.4 1 1 0 1 1 1 0 Double zinc ribbon TF_Zn_Ribbon PF08271.12 AAL63194.1 - 0.21 11.1 2.1 2.8 7.5 0.1 2.9 3 0 0 3 3 3 0 TFIIB zinc-binding zf-RRN7 PF11781.8 AAL63194.1 - 0.28 10.9 2.8 0.32 10.7 0.2 2.2 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-NADH-PPase PF09297.11 AAL63194.1 - 0.4 10.4 6.1 4.1 7.1 0.4 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain AA_permease PF00324.21 AAL63195.1 - 0.0024 16.6 2.2 0.0028 16.3 2.2 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2892 PF11127.8 AAL63195.1 - 1.3 9.1 12.5 11 6.2 7.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2892) AA_kinase PF00696.28 AAL63197.1 - 2.6e-33 115.6 0.1 3e-33 115.4 0.1 1.0 1 0 0 1 1 1 1 Amino acid kinase family polyprenyl_synt PF00348.17 AAL63198.1 - 1.7e-53 181.3 0.0 2e-53 181.1 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DUF92 PF01940.16 AAL63200.1 - 2.7e-55 187.4 14.1 3.1e-55 187.2 14.1 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 UPF0047 PF01894.17 AAL63201.1 - 6e-34 116.6 0.0 7.2e-34 116.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Polbeta PF18765.1 AAL63201.1 - 0.16 12.1 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase RP-C PF03428.13 AAL63202.1 - 0.021 14.5 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 Replication protein C N-terminal domain DUF4242 PF14026.6 AAL63203.1 - 0.063 13.5 0.2 0.17 12.0 0.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4242) AIRS PF00586.24 AAL63205.1 - 1.7e-11 44.6 0.0 2.5e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain Rib_5-P_isom_A PF06026.14 AAL63208.1 - 2.4e-53 180.3 0.0 2.8e-53 180.1 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 AAL63208.1 - 3.6e-06 27.0 0.2 1.6e-05 24.9 0.1 1.9 2 0 0 2 2 2 1 DeoR C terminal sensor domain CoA_trans PF01144.23 AAL63208.1 - 0.0041 16.5 0.1 0.081 12.3 0.0 2.1 2 0 0 2 2 2 1 Coenzyme A transferase Sugar-bind PF04198.13 AAL63208.1 - 0.0098 15.0 0.1 0.022 13.9 0.1 1.5 1 1 1 2 2 2 1 Putative sugar-binding domain Glyco_trans_4_4 PF13579.6 AAL63208.1 - 0.13 12.7 0.1 0.24 11.8 0.0 1.5 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain CBS PF00571.28 AAL63209.1 - 4.3e-29 100.7 2.7 2.8e-14 53.3 0.4 2.1 2 0 0 2 2 2 2 CBS domain AFOR_N PF02730.15 AAL63210.1 - 2.4e-36 125.5 0.2 4.3e-36 124.7 0.2 1.4 1 0 0 1 1 1 1 Aldehyde ferredoxin oxidoreductase, N-terminal domain AFOR_C PF01314.18 AAL63210.1 - 2e-14 53.4 0.0 6.3e-14 51.8 0.0 1.8 2 0 0 2 2 2 1 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 DUF4229 PF14012.6 AAL63212.1 - 0.0029 17.7 0.8 0.004 17.2 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4229) Nitro_FeMo-Co PF02579.17 AAL63214.1 - 1.6e-06 28.3 0.0 2e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Dinitrogenase iron-molybdenum cofactor Anophelin PF10731.9 AAL63215.1 - 0.24 11.3 0.0 0.41 10.5 0.0 1.4 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito 2-Hacid_dh_C PF02826.19 AAL63218.1 - 3.3e-61 205.7 0.0 5.6e-61 205.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 AAL63218.1 - 1.6e-32 112.0 0.0 1.9e-32 111.7 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 AAL63218.1 - 6.8e-05 23.1 0.0 0.00021 21.5 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 AAL63218.1 - 0.0085 16.6 0.1 0.06 13.9 0.0 2.3 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 AAL63218.1 - 0.014 15.0 0.0 0.035 13.7 0.0 1.7 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain XdhC_C PF13478.6 AAL63218.1 - 0.021 15.3 0.0 0.06 13.9 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain YAcAr PF10686.9 AAL63218.1 - 0.087 12.8 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 YspA, cpYpsA-related SLOG family POR PF01558.18 AAL63219.1 - 1.2e-36 126.5 0.1 5.8e-36 124.2 0.1 1.8 1 1 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Fer4 PF00037.27 AAL63220.1 - 1.9e-13 49.6 14.4 1.6e-07 30.8 5.2 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 AAL63220.1 - 4e-12 46.1 6.8 5.2e-12 45.7 6.8 1.1 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AAL63220.1 - 4.1e-11 43.3 28.3 4.2e-07 30.4 10.0 1.9 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.7 AAL63220.1 - 6.5e-08 32.3 12.4 0.00017 21.5 4.0 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 AAL63220.1 - 9.9e-08 32.0 17.1 1.8e-06 28.0 9.0 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAL63220.1 - 1.3e-07 32.5 8.8 0.0011 19.9 3.7 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 AAL63220.1 - 2.1e-07 30.9 9.9 1e-06 28.7 10.1 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAL63220.1 - 2.1e-06 27.5 10.7 0.0018 18.2 2.2 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 AAL63220.1 - 5.3e-05 23.6 7.8 0.00015 22.1 7.8 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_4 PF12800.7 AAL63220.1 - 0.00032 21.0 11.8 0.043 14.3 1.0 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 AAL63220.1 - 0.0013 19.2 10.7 0.21 12.2 1.4 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 AAL63220.1 - 0.0023 18.5 10.3 0.026 15.0 1.4 2.4 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_22 PF17179.4 AAL63220.1 - 0.012 16.5 9.3 0.037 14.9 1.0 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 AAL63220.1 - 0.033 14.9 12.2 32 5.4 12.2 2.5 1 1 0 1 1 1 0 4Fe-4S single cluster domain Fer4_18 PF13746.6 AAL63220.1 - 0.37 11.0 6.3 3.4 7.9 0.4 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 AAL63220.1 - 0.72 10.9 15.3 3.2 8.9 5.3 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain POR_N PF01855.19 AAL63221.1 - 2.1e-74 250.1 2.0 2.1e-74 250.1 2.0 1.4 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg PFOR_II PF17147.4 AAL63221.1 - 4.5e-30 104.0 0.2 1.2e-29 102.6 0.2 1.8 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_C PF02780.20 AAL63221.1 - 8.6e-06 25.7 0.0 2.7e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.21 AAL63222.1 - 3.7e-26 91.8 0.3 5.4e-26 91.2 0.3 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CarboxypepD_reg PF13620.6 AAL63223.1 - 4e-05 23.8 0.8 4e-05 23.8 0.8 4.4 4 1 0 4 4 4 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 AAL63223.1 - 0.0039 17.2 3.5 0.13 12.2 0.1 3.9 4 0 0 4 4 4 1 CarboxypepD_reg-like domain TIG PF01833.24 AAL63223.1 - 2.9 8.0 4.7 7.6 6.7 0.0 3.9 5 1 1 6 6 6 0 IPT/TIG domain Glyco_hydro_57 PF03065.15 AAL63225.1 - 9.3e-22 77.6 0.0 1.3e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DUF3536 PF12055.8 AAL63225.1 - 1.5e-10 40.9 0.2 2e-08 33.9 0.2 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3536) MFS_1 PF07690.16 AAL63226.1 - 1.8e-37 129.1 75.9 1.6e-30 106.2 45.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AAL63226.1 - 4.4e-05 22.5 5.5 4.4e-05 22.5 5.5 3.0 2 1 1 3 3 3 3 Sugar (and other) transporter PUCC PF03209.15 AAL63226.1 - 0.0026 16.8 3.0 0.0026 16.8 3.0 2.9 2 1 1 3 3 3 2 PUCC protein MFS_1_like PF12832.7 AAL63226.1 - 0.036 12.9 19.4 0.18 10.6 0.4 4.1 2 2 3 5 5 5 0 MFS_1 like family OATP PF03137.20 AAL63226.1 - 4.7 5.4 7.1 4.5 5.4 0.4 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family PALP PF00291.25 AAL63227.1 - 1.8e-38 132.6 0.0 7.4e-38 130.6 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme HTH_36 PF13730.6 AAL63228.1 - 0.00043 20.2 0.0 0.00084 19.2 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 AAL63228.1 - 0.048 13.5 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 MarR family ThiF PF00899.21 AAL63229.1 - 2.9e-62 210.2 0.0 3.6e-62 209.9 0.0 1.0 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 AAL63229.1 - 0.077 13.3 1.2 0.35 11.1 1.2 1.9 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GDPD PF03009.17 AAL63230.1 - 3.1e-31 109.0 0.1 9.7e-23 81.2 0.0 2.1 1 1 1 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 AAL63230.1 - 1.5e-05 25.2 2.0 1.5e-05 25.2 2.0 2.1 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family AAA_15 PF13175.6 AAL63231.1 - 1.2e-12 48.3 0.0 1.2e-12 48.3 0.0 1.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 AAL63231.1 - 5.2e-11 43.4 0.0 6.8e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 AAL63231.1 - 4.3e-10 39.4 0.0 6.2e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AAL63231.1 - 7.9e-08 32.5 0.1 8.6e-08 32.3 0.1 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AAL63231.1 - 0.001 18.7 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF2813 PF11398.8 AAL63231.1 - 0.0064 15.8 0.0 0.0073 15.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2813) AAA_27 PF13514.6 AAL63231.1 - 0.0065 16.1 0.0 0.0077 15.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 AAL63231.1 - 0.038 14.5 0.0 0.043 14.3 0.0 1.1 1 0 0 1 1 1 0 ABC transporter ABC_ATPase PF09818.9 AAL63231.1 - 0.1 11.4 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Predicted ATPase of the ABC class TniB PF05621.11 AAL63231.1 - 0.1 12.0 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Bacterial TniB protein BPD_transp_1 PF00528.22 AAL63232.1 - 7.5e-25 87.7 41.3 6.6e-14 52.1 12.8 2.9 2 1 0 2 2 2 2 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 AAL63233.1 - 2.8e-34 118.6 0.0 3.8e-34 118.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAL63233.1 - 8e-11 42.3 0.1 0.00018 21.4 0.1 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AAL63233.1 - 7.5e-05 23.2 0.1 0.00015 22.2 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AAL63233.1 - 0.00043 20.2 0.0 0.00093 19.1 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 AAL63233.1 - 0.0005 19.8 0.0 0.00094 18.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 AAL63233.1 - 0.00091 19.7 0.0 0.014 15.8 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AAL63233.1 - 0.0011 19.2 0.0 0.0046 17.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 AAL63233.1 - 0.0088 15.5 0.0 2.3 7.6 0.0 2.1 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 AAL63233.1 - 0.013 15.8 0.1 0.029 14.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AAL63233.1 - 0.018 15.6 0.1 0.026 15.0 0.1 1.2 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 AAL63233.1 - 0.019 14.9 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain ATPase_2 PF01637.18 AAL63233.1 - 0.021 14.7 0.0 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea ABC_ATPase PF09818.9 AAL63233.1 - 0.027 13.3 0.4 0.12 11.1 0.0 2.0 2 1 0 2 2 2 0 Predicted ATPase of the ABC class NACHT PF05729.12 AAL63233.1 - 0.029 14.3 0.0 0.082 12.8 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_5 PF07728.14 AAL63233.1 - 0.058 13.4 0.1 0.26 11.3 0.1 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 AAL63233.1 - 0.077 12.6 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 AAL63233.1 - 0.079 12.1 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 AAL63233.1 - 0.1 13.1 0.1 0.46 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 AAL63233.1 - 0.11 12.6 0.1 0.43 10.7 0.1 2.0 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 AAL63233.1 - 0.17 12.0 0.0 0.4 10.8 0.0 1.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF2614 PF11023.8 AAL63235.1 - 0.72 10.0 3.9 2.3 8.4 0.6 2.3 2 0 0 2 2 2 0 Zinc-ribbon containing domain AAA_assoc_C PF09821.9 AAL63236.1 - 1.7e-19 70.5 0.1 2.3e-19 70.1 0.1 1.2 1 0 0 1 1 1 1 C-terminal AAA-associated domain DUF2240 PF09999.9 AAL63236.1 - 0.0067 16.1 0.2 2.3 7.9 0.1 2.4 1 1 1 2 2 2 2 Uncharacterized protein conserved in archaea (DUF2240) HemN_C PF06969.16 AAL63236.1 - 0.01 15.9 0.1 0.98 9.5 0.0 2.9 2 1 1 3 3 3 0 HemN C-terminal domain HTH_34 PF13601.6 AAL63236.1 - 0.018 15.2 0.0 18 5.6 0.0 3.0 2 1 0 2 2 2 0 Winged helix DNA-binding domain eIF-1a PF01176.19 AAL63237.1 - 1.4e-23 82.5 0.2 1.7e-23 82.2 0.2 1.1 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 AHJR-like PF18743.1 AAL63238.1 - 0.0041 16.7 0.0 0.006 16.1 0.0 1.2 1 0 0 1 1 1 1 REase_AHJR-like Hjc PF01870.18 AAL63238.1 - 0.18 11.8 0.1 0.44 10.6 0.0 1.6 1 1 1 2 2 2 0 Archaeal holliday junction resolvase (hjc) DUF4065 PF13274.6 AAL63239.1 - 6.1e-07 30.3 0.0 4e-06 27.7 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF4065) RTP PF02334.16 AAL63239.1 - 0.084 13.5 1.0 0.37 11.5 0.0 2.4 2 1 1 3 3 3 0 Replication terminator protein Helicase_C_3 PF13625.6 AAL63239.1 - 0.18 11.9 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Helicase conserved C-terminal domain PaRep2b PF07775.11 AAL63240.1 - 6.3e-29 100.8 0.0 6.7e-26 90.8 0.0 2.0 1 1 1 2 2 2 2 PaRep2b protein OrfB_Zn_ribbon PF07282.11 AAL63241.1 - 2.9e-09 36.7 0.1 5.6e-09 35.8 0.1 1.4 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Prok-RING_1 PF14446.6 AAL63241.1 - 0.0092 15.9 0.5 0.015 15.2 0.5 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 DZR PF12773.7 AAL63241.1 - 0.027 14.5 0.3 0.044 13.8 0.3 1.2 1 0 0 1 1 1 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 AAL63241.1 - 0.063 13.3 0.2 0.097 12.7 0.2 1.2 1 0 0 1 1 1 0 zinc-ribbons DUF1272 PF06906.11 AAL63241.1 - 0.18 11.9 2.0 0.37 10.9 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1272) Auto_anti-p27 PF06677.12 AAL63241.1 - 0.38 10.9 3.6 0.98 9.6 3.6 1.7 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Zn-ribbon_8 PF09723.10 AAL63241.1 - 3.2 8.0 5.1 7.2 6.8 3.2 2.3 2 1 1 3 3 3 0 Zinc ribbon domain zf-C2H2_9 PF16293.5 AAL63241.1 - 3.2 7.7 4.1 17 5.3 3.0 2.8 2 1 0 2 2 2 0 C2H2 type zinc-finger (1 copy) DUF3087 PF11286.8 AAL63243.1 - 0.11 11.9 0.6 0.18 11.3 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) Peptidase_U4 PF03419.13 AAL63245.1 - 1.1 8.5 7.4 1.2 8.4 7.4 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Radical_SAM PF04055.21 AAL63246.1 - 6.9e-11 42.8 0.0 2.1e-10 41.3 0.0 1.8 1 1 1 2 2 2 1 Radical SAM superfamily DUF1848 PF08902.11 AAL63246.1 - 1.8e-08 34.4 1.1 0.00044 20.0 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1848) ATPase PF06745.13 AAL63247.1 - 8.7e-17 61.2 0.0 1.3e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.6 AAL63247.1 - 1.8e-08 34.2 0.1 3.6e-08 33.2 0.1 1.6 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 AAL63247.1 - 5.4e-05 23.0 0.0 9.7e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein DnaB_C PF03796.15 AAL63247.1 - 9.1e-05 21.9 0.0 0.00048 19.5 0.0 2.0 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_30 PF13604.6 AAL63247.1 - 0.00084 19.1 0.1 0.0022 17.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain Elong_Iki1 PF10483.9 AAL63247.1 - 0.00088 18.9 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 Elongator subunit Iki1 Sigma54_activat PF00158.26 AAL63247.1 - 0.0019 17.9 0.0 0.0033 17.1 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain CbiA PF01656.23 AAL63247.1 - 0.023 14.8 0.0 0.031 14.3 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54 PF00448.22 AAL63247.1 - 0.046 13.3 0.0 0.081 12.5 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NACHT PF05729.12 AAL63247.1 - 0.087 12.7 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain TsaE PF02367.17 AAL63247.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IGR PF09597.10 AAL63247.1 - 0.16 12.1 0.1 0.4 10.8 0.1 1.7 1 0 0 1 1 1 0 IGR protein motif FSA_C PF10479.9 AAL63247.1 - 0.18 9.9 0.0 0.23 9.5 0.0 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Metallophos_2 PF12850.7 AAL63249.1 - 2e-16 60.6 0.0 2.8e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 AAL63249.1 - 5.4e-12 45.6 2.0 2.5e-11 43.4 2.0 2.0 1 1 0 1 1 1 1 Metallophosphoesterase, calcineurin superfamily Metallophos PF00149.28 AAL63249.1 - 4.9e-09 37.0 0.2 2.5e-08 34.7 0.2 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase BclA_C PF18573.1 AAL63252.1 - 0.24 11.3 8.7 0.32 10.9 0.9 3.1 3 0 0 3 3 3 0 BclA C-terminal domain QCR10 PF09796.9 AAL63253.1 - 5.4e-05 23.2 1.5 0.0054 16.8 0.1 2.9 2 1 1 3 3 3 2 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) FtsK_4TM PF13491.6 AAL63253.1 - 0.024 14.4 1.7 0.024 14.4 1.7 2.2 1 1 1 2 2 2 0 4TM region of DNA translocase FtsK/SpoIIIE Rhomboid PF01694.22 AAL63254.1 - 5.8e-38 130.2 21.1 5.8e-38 130.2 21.1 1.4 2 0 0 2 2 2 1 Rhomboid family DoxX_3 PF13781.6 AAL63254.1 - 4.7 7.9 15.8 0.21 12.3 8.8 2.3 2 1 0 3 3 3 0 DoxX-like family NNMT_PNMT_TEMT PF01234.17 AAL63255.1 - 0.043 13.0 0.0 0.053 12.7 0.0 1.1 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family HTH_20 PF12840.7 AAL63255.1 - 0.11 12.5 0.0 0.57 10.3 0.0 2.2 3 0 0 3 3 3 0 Helix-turn-helix domain Glyoxalase_4 PF13669.6 AAL63255.1 - 0.17 12.2 0.0 0.44 10.9 0.0 1.6 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily PIN PF01850.21 AAL63256.1 - 0.00061 20.3 1.6 0.0029 18.1 1.6 2.0 1 1 0 1 1 1 1 PIN domain HTH_24 PF13412.6 AAL63257.1 - 1.5e-05 24.5 0.0 4.3e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 AAL63257.1 - 7e-05 22.6 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_45 PF14947.6 AAL63257.1 - 0.015 15.3 0.0 0.019 14.9 0.0 1.3 1 1 0 1 1 1 0 Winged helix-turn-helix DUF3116 PF11313.8 AAL63257.1 - 0.075 12.9 0.3 0.19 11.6 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3116) HTH_CodY PF08222.11 AAL63257.1 - 0.086 12.4 0.1 12 5.5 0.2 2.5 1 1 2 3 3 3 0 CodY helix-turn-helix domain TRF PF08558.10 AAL63257.1 - 0.094 12.3 0.0 0.094 12.3 0.0 1.2 1 0 0 1 1 1 0 Telomere repeat binding factor (TRF) TrmB PF01978.19 AAL63257.1 - 0.097 12.6 0.0 0.12 12.3 0.0 1.4 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB LexA_DNA_bind PF01726.16 AAL63257.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 LexA DNA binding domain NfeD PF01957.18 AAL63258.1 - 5.2e-10 39.6 1.1 5.2e-10 39.6 1.1 1.4 2 0 0 2 2 2 1 NfeD-like C-terminal, partner-binding Methyltransf_25 PF13649.6 AAL63259.1 - 0.00012 22.7 0.0 0.00017 22.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAL63259.1 - 0.0067 17.0 0.0 0.0097 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AAL63259.1 - 0.021 14.4 0.1 0.028 14.0 0.1 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.6 AAL63259.1 - 0.1 12.4 0.0 0.26 11.1 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain MetW PF07021.12 AAL63259.1 - 0.12 12.0 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_23 PF13489.6 AAL63259.1 - 0.19 11.5 0.0 0.32 10.8 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 AAL63259.1 - 0.29 10.5 0.0 0.43 9.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) tRNA-synt_1 PF00133.22 AAL63260.1 - 1.3e-58 198.8 0.0 3.7e-49 167.5 0.0 2.5 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 AAL63260.1 - 3.8e-28 98.4 0.1 5.2e-12 45.2 0.0 3.2 2 1 1 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 AAL63260.1 - 3.9e-15 56.1 0.0 8.4e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.6 AAL63260.1 - 1.2e-10 41.2 0.0 2.3e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 AAL63260.1 - 2.3e-09 37.1 0.0 8.3e-06 25.4 0.0 2.5 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 AAL63260.1 - 0.012 14.6 0.0 0.16 10.9 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (K) Topoisom_bac PF01131.20 AAL63261.1 - 6.8e-76 255.9 0.2 2.3e-75 254.2 0.0 1.9 2 0 0 2 2 2 1 DNA topoisomerase Toprim PF01751.22 AAL63261.1 - 1.9e-20 73.0 0.0 8.7e-20 70.9 0.0 2.3 1 0 0 1 1 1 1 Toprim domain DEAD PF00270.29 AAL63261.1 - 6.6e-16 58.6 0.0 2.5e-15 56.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf_Rg PF17915.1 AAL63261.1 - 2.7e-13 49.1 0.8 5.9e-13 48.0 0.8 1.5 1 0 0 1 1 1 1 Reverse gyrase zinc finger Helicase_C PF00271.31 AAL63261.1 - 1.3e-07 32.0 0.0 0.00075 19.8 0.0 3.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 AAL63261.1 - 1e-05 25.6 0.0 2.1e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 AAL63261.1 - 0.02 15.3 0.0 0.045 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Toprim_4 PF13662.6 AAL63261.1 - 0.021 15.3 0.1 0.8 10.2 0.0 3.1 2 0 0 2 2 2 0 Toprim domain AAA_30 PF13604.6 AAL63261.1 - 0.049 13.3 1.1 0.072 12.8 0.1 1.7 2 0 0 2 2 2 0 AAA domain DUF1640 PF07798.11 AAL63261.1 - 0.068 13.2 0.3 0.16 12.0 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) SecA_DEAD PF07517.14 AAL63261.1 - 0.077 12.3 0.1 0.24 10.7 0.0 1.7 1 1 0 1 1 1 0 SecA DEAD-like domain CbiA PF01656.23 AAL63261.1 - 0.094 12.8 0.0 23 5.1 0.0 3.0 2 2 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF87 PF01935.17 AAL63261.1 - 0.14 12.2 0.1 0.42 10.7 0.1 1.8 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_23 PF13476.6 AAL63261.1 - 1.2 9.6 2.3 1.5 9.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain Macro PF01661.21 AAL63263.1 - 2.2e-37 127.7 0.2 2.9e-37 127.3 0.2 1.1 1 0 0 1 1 1 1 Macro domain Phage_Treg PF04761.12 AAL63263.1 - 0.022 14.9 0.0 2.7 8.2 0.0 2.3 2 0 0 2 2 2 0 Lactococcus bacteriophage putative transcription regulator Sel_put PF04328.13 AAL63263.1 - 0.15 12.1 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Selenoprotein, putative LtuA PF17446.2 AAL63263.1 - 0.18 12.2 0.7 0.34 11.3 0.7 1.4 1 0 0 1 1 1 0 Late transcription unit A Radical_SAM PF04055.21 AAL63264.1 - 2.3e-15 57.4 0.0 4.1e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily B12-binding PF02310.19 AAL63264.1 - 2.5e-10 40.4 0.0 7.3e-10 38.9 0.0 1.8 1 0 0 1 1 1 1 B12 binding domain DNA_pol_B PF00136.21 AAL63265.1 - 0.0001 21.2 0.0 0.27 9.9 0.0 2.1 2 0 0 2 2 2 2 DNA polymerase family B DKCLD PF08068.12 AAL63266.1 - 0.16 12.1 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 DKCLD (NUC011) domain PaREP1 PF05942.11 AAL63268.1 - 2.1e-14 53.4 0.3 2.1e-14 53.4 0.3 1.1 1 0 0 1 1 1 1 Archaeal PaREP1/PaREP8 family ATPase_2 PF01637.18 AAL63269.1 - 1.2e-19 71.1 0.0 6.4e-18 65.5 0.0 2.4 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea DUF234 PF03008.14 AAL63269.1 - 3.3e-13 49.9 0.0 2.1e-12 47.4 0.0 2.1 2 0 0 2 2 2 1 Archaea bacterial proteins of unknown function AAA_14 PF13173.6 AAL63269.1 - 8.7e-07 29.0 0.0 1.6e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAL63269.1 - 4.2e-06 27.2 1.7 0.00011 22.6 0.6 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 AAL63269.1 - 2.5e-05 24.5 0.0 8.7e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain HTH_20 PF12840.7 AAL63269.1 - 0.00011 22.2 0.0 0.00052 20.0 0.0 2.2 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.19 AAL63269.1 - 0.00039 20.2 0.1 0.0069 16.2 0.0 2.4 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 AAL63269.1 - 0.00043 19.8 0.2 0.0018 17.8 0.1 2.1 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Rrf2 PF02082.20 AAL63269.1 - 0.0026 18.0 0.0 0.098 13.0 0.0 2.4 2 0 0 2 2 2 1 Transcriptional regulator MarR_2 PF12802.7 AAL63269.1 - 0.0069 16.3 2.2 0.08 12.8 0.1 2.9 3 0 0 3 3 3 1 MarR family HTH_IclR PF09339.10 AAL63269.1 - 0.011 15.5 0.5 0.11 12.3 0.1 2.5 2 0 0 2 2 2 0 IclR helix-turn-helix domain TniB PF05621.11 AAL63269.1 - 0.015 14.7 0.0 0.081 12.3 0.0 2.2 2 1 0 2 2 2 0 Bacterial TniB protein CENP-B_N PF04218.13 AAL63269.1 - 0.029 14.0 0.0 0.058 13.0 0.0 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain DUF4423 PF14394.6 AAL63269.1 - 0.049 13.3 0.0 0.21 11.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) HTH_45 PF14947.6 AAL63269.1 - 0.049 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix HTH_27 PF13463.6 AAL63269.1 - 0.2 12.2 0.3 1.5 9.3 0.0 2.6 3 0 0 3 3 3 0 Winged helix DNA-binding domain Rhomboid PF01694.22 AAL63270.1 - 6.6e-30 104.1 6.9 6.6e-30 104.1 6.9 1.7 2 0 0 2 2 2 1 Rhomboid family DUF1751 PF08551.10 AAL63270.1 - 0.048 14.2 0.1 0.048 14.2 0.1 1.8 2 0 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) TSC22 PF01166.18 AAL63270.1 - 0.21 11.9 0.2 0.35 11.2 0.2 1.3 1 0 0 1 1 1 0 TSC-22/dip/bun family GlgS PF08971.11 AAL63270.1 - 0.23 11.5 1.3 0.5 10.4 1.3 1.5 1 0 0 1 1 1 0 Glycogen synthesis protein ATG_C PF09333.11 AAL63270.1 - 0.25 11.7 0.6 3.8 7.9 0.3 2.1 2 0 0 2 2 2 0 Autophagy-related protein C terminal domain Aldo_ket_red PF00248.21 AAL63272.1 - 9.2e-30 103.8 0.0 2.4e-29 102.4 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family DUF996 PF06195.13 AAL63273.1 - 1.4e-37 129.0 17.6 1.4e-37 129.0 17.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF996) UbiA PF01040.18 AAL63273.1 - 1.8 7.8 28.1 2.8 7.2 28.1 1.2 1 0 0 1 1 1 0 UbiA prenyltransferase family DUF973 PF06157.11 AAL63273.1 - 6 5.8 20.5 0.5 9.4 9.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF973) Pyr_redox_2 PF07992.14 AAL63275.1 - 3e-18 66.1 0.4 3.4e-17 62.6 0.4 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAL63275.1 - 5.4e-06 26.9 2.3 0.027 15.0 0.2 2.6 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AAL63275.1 - 0.00012 21.8 3.5 0.024 14.2 0.2 3.1 2 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 AAL63275.1 - 0.0024 17.9 0.2 0.092 12.7 0.2 2.5 1 1 1 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 AAL63275.1 - 0.0097 15.0 0.0 0.024 13.7 0.0 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_7 PF13241.6 AAL63275.1 - 0.021 15.2 0.2 0.053 14.0 0.1 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding Trp_halogenase PF04820.14 AAL63275.1 - 0.095 11.5 0.2 0.16 10.8 0.2 1.3 1 0 0 1 1 1 0 Tryptophan halogenase TrkA_N PF02254.18 AAL63275.1 - 0.11 12.8 0.8 0.29 11.4 0.1 2.1 3 0 0 3 3 3 0 TrkA-N domain FAD_binding_2 PF00890.24 AAL63275.1 - 0.15 11.1 0.1 0.36 9.8 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain Shikimate_DH PF01488.20 AAL63275.1 - 0.2 11.7 0.3 0.36 10.9 0.3 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 AAL63275.1 - 0.56 9.5 3.0 0.96 8.7 2.9 1.5 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF2678 PF10856.8 AAL63276.1 - 9.4 6.2 13.0 0.59 10.1 1.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) TP_methylase PF00590.20 AAL63277.1 - 2.2e-32 112.7 0.3 2.6e-32 112.5 0.3 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Phosphatase PF15698.5 AAL63277.1 - 0.0046 16.1 0.0 0.096 11.8 0.0 2.1 1 1 0 1 1 1 1 Phosphatase TPP_enzyme_M PF00205.22 AAL63277.1 - 0.0059 16.3 0.1 0.26 11.0 0.1 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Fer4_12 PF13353.6 AAL63277.1 - 0.2 11.9 0.0 0.3 11.3 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S single cluster domain Molydop_binding PF01568.21 AAL63278.1 - 6.2e-06 26.2 0.1 8.4e-06 25.8 0.1 1.3 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Rad9_Rad53_bind PF08605.10 AAL63278.1 - 0.011 15.9 0.0 0.015 15.4 0.0 1.2 1 0 0 1 1 1 0 Fungal Rad9-like Rad53-binding DUF1451 PF07295.11 AAL63279.1 - 0.028 14.5 0.1 0.3 11.1 0.0 2.2 1 1 1 2 2 2 0 Zinc-ribbon containing domain PseudoU_synth_1 PF01416.20 AAL63280.1 - 7.3e-19 68.2 0.0 1.8e-18 66.9 0.0 1.7 2 0 0 2 2 2 1 tRNA pseudouridine synthase Acetyltransf_1 PF00583.25 AAL63281.1 - 1.1e-12 48.2 0.0 1.6e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 AAL63281.1 - 2.4e-07 30.6 0.1 3.6e-07 30.0 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 AAL63281.1 - 3.1e-06 27.2 0.0 4.3e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAL63281.1 - 1.2e-05 25.6 0.0 2e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 AAL63281.1 - 0.0001 22.0 0.0 0.00015 21.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_9 PF13527.7 AAL63281.1 - 0.0011 19.1 0.1 0.015 15.4 0.1 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AAL63281.1 - 0.0011 19.6 0.4 0.03 15.0 0.4 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AAL63281.1 - 0.0012 18.9 0.0 0.0021 18.2 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_6 PF13480.7 AAL63281.1 - 0.0035 17.5 0.3 0.0058 16.8 0.3 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4148 PF13663.6 AAL63282.1 - 0.21 11.8 0.0 0.38 11.0 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) NAD_binding_2 PF03446.15 AAL63283.1 - 7.6e-50 169.2 0.1 1.4e-49 168.3 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 AAL63283.1 - 1.2e-29 103.1 0.7 1.6e-29 102.6 0.7 1.2 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 AAL63283.1 - 4.2e-05 23.0 0.2 0.00011 21.6 0.0 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 AAL63283.1 - 0.00029 21.4 0.0 0.00063 20.3 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 AAL63283.1 - 0.00067 19.3 0.1 0.0014 18.3 0.0 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA GFO_IDH_MocA PF01408.22 AAL63283.1 - 0.0015 19.4 0.0 0.0028 18.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Shikimate_DH PF01488.20 AAL63283.1 - 0.0015 18.6 0.0 0.0028 17.7 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 AAL63283.1 - 0.019 14.9 0.2 0.037 13.9 0.2 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh PF00984.19 AAL63283.1 - 0.033 14.4 0.0 0.066 13.4 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain DUF1967 PF09269.11 AAL63283.1 - 0.17 11.8 0.0 0.7 9.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) ATP-synt_ab PF00006.25 AAL63284.1 - 4.9e-63 212.6 0.0 6.5e-63 212.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 AAL63284.1 - 8.3e-08 32.6 2.6 2.1e-07 31.3 2.6 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain STAR_dimer PF16544.5 AAL63285.1 - 0.19 11.3 0.1 0.38 10.3 0.1 1.6 1 0 0 1 1 1 0 Homodimerisation region of STAR domain protein NTP_transf_2 PF01909.23 AAL63287.1 - 9e-12 45.1 0.1 1.1e-11 44.9 0.1 1.1 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 AAL63287.1 - 2.7e-09 37.0 0.0 3.3e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase Glyco_trans_4_4 PF13579.6 AAL63287.1 - 0.093 13.2 0.2 0.11 13.0 0.2 1.1 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 AAL63287.1 - 0.11 12.5 0.1 0.15 12.1 0.1 1.1 1 0 0 1 1 1 0 Glycosyltransferase Family 4 DUF294 PF03445.13 AAL63287.1 - 0.11 12.3 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative nucleotidyltransferase DUF294 BolA PF01722.18 AAL63287.1 - 0.13 12.5 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 BolA-like protein HEPN PF05168.14 AAL63288.1 - 1.4e-29 102.6 0.3 1.7e-29 102.4 0.3 1.0 1 0 0 1 1 1 1 HEPN domain ATPase PF06745.13 AAL63289.1 - 1.4e-43 148.9 1.3 1.4e-41 142.3 1.3 2.3 1 1 0 1 1 1 1 KaiC Rad51 PF08423.11 AAL63289.1 - 4.6e-07 29.4 0.0 3.9e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 Rad51 AAA_25 PF13481.6 AAL63289.1 - 1.9e-06 27.6 0.0 6.2e-06 25.9 0.0 2.0 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 AAL63289.1 - 5.4e-06 26.3 0.0 1.5e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 IstB-like ATP binding protein GvpD PF07088.11 AAL63289.1 - 6.8e-06 25.0 0.0 1.9e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 GvpD gas vesicle protein DnaB_C PF03796.15 AAL63289.1 - 7e-05 22.3 0.0 0.0006 19.2 0.0 2.2 2 1 1 3 3 3 1 DnaB-like helicase C terminal domain RecA PF00154.21 AAL63289.1 - 0.00056 19.5 0.0 0.00078 19.0 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_16 PF13191.6 AAL63289.1 - 0.0013 19.1 0.0 0.0025 18.2 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain PAXNEB PF05625.11 AAL63289.1 - 0.0013 17.9 0.0 0.042 13.0 0.0 2.1 1 1 0 2 2 2 1 PAXNEB protein AAA_22 PF13401.6 AAL63289.1 - 0.0024 18.1 0.1 0.014 15.7 0.0 2.1 2 1 0 3 3 3 1 AAA domain AAA_24 PF13479.6 AAL63289.1 - 0.0028 17.4 0.1 0.069 12.9 0.0 2.7 1 1 0 2 2 2 1 AAA domain DUF2075 PF09848.9 AAL63289.1 - 0.004 16.5 0.0 0.0067 15.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.7 AAL63289.1 - 0.0065 15.4 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain DAP3 PF10236.9 AAL63289.1 - 0.0066 15.6 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 MMR_HSR1 PF01926.23 AAL63289.1 - 0.01 15.9 0.0 0.025 14.6 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase MEDS PF14417.6 AAL63289.1 - 0.023 14.5 0.0 0.074 12.9 0.0 1.8 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain AAA_30 PF13604.6 AAL63289.1 - 0.023 14.4 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 AAL63289.1 - 0.047 13.7 0.0 0.52 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.6 AAL63289.1 - 0.065 13.3 0.0 4.9 7.3 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.6 AAL63289.1 - 0.07 13.7 0.1 0.3 11.6 0.0 2.2 2 1 0 2 2 1 0 AAA domain MeaB PF03308.16 AAL63289.1 - 0.077 12.0 1.6 1.1 8.2 0.1 2.7 2 1 1 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 AAL63289.1 - 0.12 12.9 0.0 0.24 11.9 0.0 1.8 1 1 0 1 1 1 0 ABC transporter Thiamine_BP PF01910.17 AAL63290.1 - 1.9e-29 101.4 0.1 2.1e-29 101.3 0.1 1.0 1 0 0 1 1 1 1 Thiamine-binding protein MazG PF03819.17 AAL63291.1 - 2.4e-07 30.8 0.4 3.6e-07 30.3 0.4 1.3 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain MazG-like PF12643.7 AAL63291.1 - 1.5e-05 25.2 0.1 2.1e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 MazG-like family dUTPase_2 PF08761.11 AAL63291.1 - 0.026 14.7 0.3 0.55 10.4 0.0 2.0 2 0 0 2 2 2 0 dUTPase FHA PF00498.26 AAL63292.1 - 1e-15 57.8 0.0 1.3e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 AAL63292.1 - 1.7e-06 28.3 0.0 2.3e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Thioredoxin_3 PF13192.6 AAL63293.1 - 5.2e-05 23.2 0.0 0.018 15.0 0.0 2.1 2 0 0 2 2 2 2 Thioredoxin domain Radical_SAM PF04055.21 AAL63294.1 - 1.1e-14 55.2 0.0 1.9e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Radical_SAM PF04055.21 AAL63295.1 - 2.7e-18 66.9 0.1 7.3e-18 65.5 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily Methyltransf_11 PF08241.12 AAL63296.1 - 8.5e-20 71.2 0.0 1.2e-19 70.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAL63296.1 - 8.3e-15 55.0 0.0 1.1e-14 54.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAL63296.1 - 3e-14 53.5 0.0 4.2e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAL63296.1 - 1.6e-12 48.0 0.0 2.5e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAL63296.1 - 6.8e-09 35.7 0.0 9.3e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AAL63296.1 - 2e-08 33.8 0.0 2.4e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 AAL63296.1 - 1.9e-05 24.4 0.0 2.4e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_8 PF05148.15 AAL63296.1 - 0.085 12.7 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase VitK2_biosynth PF02621.14 AAL63297.1 - 1.1e-17 64.5 0.0 1.3e-17 64.2 0.0 1.1 1 0 0 1 1 1 1 Menaquinone biosynthesis Bcl-2 PF00452.19 AAL63297.1 - 0.13 13.0 0.0 0.21 12.3 0.0 1.3 1 0 0 1 1 1 0 Apoptosis regulator proteins, Bcl-2 family ABC_tran PF00005.27 AAL63298.1 - 1.3e-19 71.1 0.0 1.8e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAL63298.1 - 3.9e-11 43.3 0.1 7.1e-05 22.7 0.2 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SRP54 PF00448.22 AAL63298.1 - 0.0064 16.1 0.1 0.015 14.9 0.1 1.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 AAL63298.1 - 0.012 15.4 0.2 0.023 14.4 0.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AAL63298.1 - 0.027 15.0 0.0 0.046 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AAL63298.1 - 0.046 13.4 0.0 0.093 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 AAL63298.1 - 0.057 13.8 0.0 0.095 13.1 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AAL63298.1 - 0.074 13.4 0.0 0.17 12.2 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.19 AAL63298.1 - 0.1 12.0 0.2 8.8 5.7 0.1 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 AAL63298.1 - 0.11 12.2 0.0 0.25 11.0 0.0 1.4 1 1 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 AAL63298.1 - 0.13 12.5 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AAL63298.1 - 0.14 12.4 0.1 0.22 11.8 0.1 1.6 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 AAL63298.1 - 0.16 11.2 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Rad17 PF03215.15 AAL63298.1 - 0.17 11.8 0.0 0.65 9.9 0.0 1.8 2 0 0 2 2 2 0 Rad17 P-loop domain ABC2_membrane_3 PF12698.7 AAL63299.1 - 6e-10 38.7 20.0 9.9e-10 38.0 19.9 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 AAL63299.1 - 2.5e-06 27.0 30.1 6.4e-06 25.7 30.1 1.7 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 AAL63299.1 - 2.4e-05 23.8 19.1 2.4e-05 23.8 19.1 2.8 2 1 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_4 PF12730.7 AAL63299.1 - 0.00029 20.8 14.7 0.00029 20.8 14.7 2.7 2 1 1 3 3 3 1 ABC-2 family transporter protein ABC2_membrane_5 PF13346.6 AAL63299.1 - 0.064 12.8 22.0 0.019 14.5 17.5 2.2 2 1 0 2 2 2 0 ABC-2 family transporter protein 2-Hacid_dh_C PF02826.19 AAL63301.1 - 1.2e-36 125.7 0.0 1.9e-36 125.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 AAL63301.1 - 1.4e-11 44.2 0.0 1.7e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 AAL63301.1 - 0.00029 21.0 0.0 0.00057 20.1 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 AAL63301.1 - 0.0014 18.6 0.0 0.0031 17.5 0.0 1.6 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 AAL63301.1 - 0.041 14.5 0.4 0.49 11.0 0.2 2.6 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 AAL63301.1 - 0.074 13.1 0.3 1.4 9.0 0.3 2.2 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AlaDh_PNT_C PF01262.21 AAL63301.1 - 0.089 12.1 0.0 2 7.7 0.1 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Leuk-A4-hydro_C PF09127.11 AAL63302.1 - 0.052 13.6 0.0 0.066 13.3 0.0 1.2 1 0 0 1 1 1 0 Leukotriene A4 hydrolase, C-terminal PaRep2b PF07775.11 AAL63304.1 - 1.1e-20 73.6 0.1 1.2e-20 73.5 0.1 1.0 1 0 0 1 1 1 1 PaRep2b protein PaRep2b PF07775.11 AAL63305.1 - 2.4e-221 735.7 10.8 2.4e-221 735.7 10.8 1.9 2 0 0 2 2 2 1 PaRep2b protein EzrA PF06160.12 AAL63305.1 - 4.2e-05 21.9 1.4 5.3e-05 21.6 0.2 1.7 2 0 0 2 2 2 1 Septation ring formation regulator, EzrA PASTA PF03793.19 AAL63305.1 - 0.15 11.9 0.8 5.6 6.9 0.0 3.5 2 1 1 3 3 3 0 PASTA domain SPOR PF05036.13 AAL63305.1 - 3.3 8.1 6.8 5.5 7.5 0.1 3.5 3 0 0 3 3 3 0 Sporulation related domain PaRep2a PF07903.11 AAL63306.1 - 2.8e-64 214.4 2.2 5.3e-64 213.5 2.2 1.5 1 0 0 1 1 1 1 PaRep2a protein Ribosomal_S5 PF00333.20 AAL63307.1 - 1.1e-24 86.2 1.0 1.1e-24 86.2 1.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 AAL63307.1 - 7.4e-24 83.0 0.1 1.5e-23 82.0 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_L30 PF00327.20 AAL63308.1 - 9.8e-13 47.8 0.2 1.7e-12 47.0 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e VbhA PF18495.1 AAL63308.1 - 0.086 12.7 0.1 7.6 6.5 0.0 2.4 2 0 0 2 2 2 0 Antitoxin VbhA GalP_UDP_transf PF01087.22 AAL63309.1 - 6.5e-19 69.1 0.0 6.2e-18 65.9 0.0 2.4 2 1 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 AAL63309.1 - 1.2e-13 51.2 0.2 2e-13 50.4 0.2 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.23 AAL63309.1 - 0.00072 20.2 0.1 0.75 10.6 0.0 2.4 2 0 0 2 2 2 2 HIT domain DUF4931 PF16285.5 AAL63309.1 - 0.001 18.4 0.0 0.0028 17.0 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4931) DcpS_C PF11969.8 AAL63309.1 - 0.0022 18.4 0.3 0.01 16.3 0.3 1.9 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding GHMP_kinases_N PF00288.26 AAL63310.1 - 4.9e-14 52.3 1.8 8.4e-14 51.6 0.5 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 AAL63310.1 - 3.5e-13 49.7 0.5 1.1e-12 48.2 0.1 1.9 2 0 0 2 2 2 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 AAL63310.1 - 4.5e-06 26.1 0.0 1e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature TetR_C_22 PF17928.1 AAL63310.1 - 0.027 14.8 0.4 4.9 7.5 0.1 2.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Peptidase_M50 PF02163.22 AAL63311.1 - 3.1e-09 36.5 12.5 6.3e-07 28.9 0.4 3.1 2 1 1 3 3 3 3 Peptidase family M50 AbiEi_4 PF13338.6 AAL63312.1 - 0.011 15.8 0.0 0.024 14.8 0.0 1.6 1 1 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin EAP30 PF04157.16 AAL63312.1 - 0.12 11.7 0.2 0.15 11.3 0.2 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family Peptidase_S9 PF00326.21 AAL63313.1 - 1.7e-41 142.0 0.0 2.3e-41 141.6 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 AAL63313.1 - 2.2e-12 46.6 0.7 8.1e-07 28.8 0.0 4.6 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Abhydrolase_1 PF00561.20 AAL63313.1 - 1.1e-11 44.9 0.0 2.3e-06 27.5 0.0 2.4 1 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 AAL63313.1 - 3e-11 43.4 0.0 3e-06 27.0 0.1 2.4 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 AAL63313.1 - 3.2e-10 39.7 0.0 3e-06 26.7 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AAL63313.1 - 1e-09 39.3 0.7 7e-08 33.3 0.7 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.14 AAL63313.1 - 1.5e-05 24.4 0.2 0.0077 15.6 0.1 2.2 2 0 0 2 2 2 2 Secretory lipase BAAT_C PF08840.11 AAL63313.1 - 0.00036 20.5 0.0 0.0024 17.8 0.0 2.0 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 AAL63313.1 - 0.00037 20.4 0.1 0.012 15.5 0.0 2.7 2 1 0 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 AAL63313.1 - 0.00041 20.0 0.0 0.00082 19.0 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family DUF2920 PF11144.8 AAL63313.1 - 0.0017 17.6 0.0 0.45 9.6 0.1 2.2 1 1 0 2 2 2 2 Protein of unknown function (DUF2920) Esterase PF00756.20 AAL63313.1 - 0.0023 17.6 0.0 0.017 14.8 0.0 2.2 1 1 0 1 1 1 1 Putative esterase PQQ_2 PF13360.6 AAL63313.1 - 0.0066 16.1 0.1 0.022 14.3 0.1 1.8 1 1 0 1 1 1 1 PQQ-like domain Abhydrolase_2 PF02230.16 AAL63313.1 - 0.015 15.2 0.1 0.35 10.6 0.0 2.4 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase PGM1_C PF18105.1 AAL63313.1 - 0.02 14.4 0.0 7.4 6.2 0.0 2.8 2 0 0 2 2 2 0 PGM1 C-terminal domain Abhydrolase_4 PF08386.10 AAL63313.1 - 0.023 14.8 0.0 0.087 12.9 0.0 1.8 2 0 0 2 2 2 0 TAP-like protein PaRep2b PF07775.11 AAL63314.1 - 7.6e-145 483.3 7.9 8.5e-145 483.1 7.9 1.0 1 0 0 1 1 1 1 PaRep2b protein Gamma_PGA_hydro PF05908.11 AAL63314.1 - 0.077 12.4 0.2 0.27 10.6 0.0 1.9 2 1 0 2 2 2 0 Poly-gamma-glutamate hydrolase ABC_tran PF00005.27 AAL63319.1 - 3.4e-16 60.0 0.0 4.9e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAL63319.1 - 8.6e-10 38.9 0.0 4.3e-05 23.5 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AAL63319.1 - 0.00068 20.2 0.4 0.0022 18.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 AAL63319.1 - 0.013 15.2 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AAL63319.1 - 0.016 14.9 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 AAL63319.1 - 0.025 15.0 0.0 0.036 14.5 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.19 AAL63319.1 - 0.034 13.6 0.2 5.9 6.3 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain TsaE PF02367.17 AAL63319.1 - 0.064 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MukB PF04310.12 AAL63319.1 - 0.076 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 MukB N-terminal cobW PF02492.19 AAL63319.1 - 0.091 12.3 0.1 0.25 10.9 0.1 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 AAL63319.1 - 0.1 12.9 0.0 0.23 11.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 AAL63319.1 - 0.16 10.9 0.1 0.69 8.8 0.1 1.9 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain YcaO PF02624.16 AAL63320.1 - 0.00088 18.6 0.1 0.00088 18.6 0.1 1.0 1 0 0 1 1 1 1 YcaO cyclodehydratase, ATP-ad Mg2+-binding Phage_min_cap2 PF06152.11 AAL63320.1 - 0.0016 17.4 0.9 0.002 17.1 0.9 1.0 1 0 0 1 1 1 1 Phage minor capsid protein 2 YojJ PF10372.9 AAL63320.1 - 0.029 14.5 0.0 0.036 14.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus DnaB_2 PF07261.11 AAL63320.1 - 0.079 12.7 0.3 0.16 11.7 0.2 1.5 1 1 0 1 1 1 0 Replication initiation and membrane attachment PaRep2a PF07903.11 AAL63321.1 - 9.8e-47 157.8 0.3 1.1e-46 157.7 0.3 1.0 1 0 0 1 1 1 1 PaRep2a protein Spermine_synth PF01564.17 AAL63322.1 - 3.9e-49 166.6 0.0 5.8e-49 166.1 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 AAL63322.1 - 2.8e-07 30.3 0.1 6.4e-07 29.2 0.1 1.6 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_12 PF08242.12 AAL63322.1 - 0.00014 22.5 0.1 0.00043 21.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAL63322.1 - 0.00028 21.5 0.0 0.0011 19.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAL63322.1 - 0.013 16.1 0.0 0.029 15.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 AAL63322.1 - 0.025 14.2 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_23 PF13489.6 AAL63322.1 - 0.041 13.7 0.0 0.087 12.6 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 AAL63322.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DFP PF04127.15 AAL63323.1 - 2.8e-48 164.2 0.0 6e-48 163.1 0.0 1.6 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein Flavoprotein PF02441.19 AAL63323.1 - 9.1e-32 110.0 0.2 1.5e-31 109.3 0.2 1.3 1 0 0 1 1 1 1 Flavoprotein YjeF_N PF03853.15 AAL63323.1 - 0.0022 17.9 0.1 0.66 9.8 0.0 2.9 1 1 2 3 3 3 2 YjeF-related protein N-terminus Pyr_redox_2 PF07992.14 AAL63323.1 - 0.039 13.2 0.0 0.7 9.1 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_trans_4_4 PF13579.6 AAL63323.1 - 0.11 12.9 1.6 0.83 10.1 0.0 2.9 2 1 0 2 2 2 0 Glycosyl transferase 4-like domain HTH_3 PF01381.22 AAL63324.1 - 5.8e-05 23.1 0.2 0.00018 21.5 0.2 1.9 1 0 0 1 1 1 1 Helix-turn-helix Rubrerythrin PF02915.17 AAL63324.1 - 0.00029 21.3 0.5 0.00096 19.6 0.2 2.1 1 1 0 2 2 2 1 Rubrerythrin Phenol_Hydrox PF02332.18 AAL63324.1 - 0.012 15.1 0.0 0.39 10.2 0.0 2.2 1 1 1 2 2 2 0 Methane/Phenol/Toluene Hydroxylase HTH_1 PF00126.27 AAL63324.1 - 0.038 13.9 2.4 0.069 13.1 0.2 2.7 3 1 0 3 3 3 0 Bacterial regulatory helix-turn-helix protein, lysR family PaREP1 PF05942.11 AAL63324.1 - 0.04 13.8 0.4 0.078 12.9 0.3 1.6 1 1 0 1 1 1 0 Archaeal PaREP1/PaREP8 family Ferritin_2 PF13668.6 AAL63324.1 - 0.084 13.1 0.0 2.8 8.1 0.0 2.7 1 1 0 1 1 1 0 Ferritin-like domain RNA_replicase_B PF03431.13 AAL63324.1 - 0.15 10.5 0.0 0.23 9.9 0.0 1.3 1 0 0 1 1 1 0 RNA replicase, beta-chain HTH_23 PF13384.6 AAL63324.1 - 0.15 11.9 1.1 0.76 9.7 0.1 2.6 3 0 0 3 3 3 0 Homeodomain-like domain HTH_31 PF13560.6 AAL63324.1 - 0.41 11.0 3.8 0.47 10.8 0.4 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain DUF1138 PF06592.13 AAL63325.1 - 0.09 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1138) Glyco_hydro_77 PF02446.17 AAL63326.1 - 1.1e-135 453.2 0.0 1.6e-135 452.6 0.0 1.2 1 0 0 1 1 1 1 4-alpha-glucanotransferase PaRep2a PF07903.11 AAL63327.1 - 7.3e-67 222.8 2.2 7.3e-67 222.8 2.2 1.8 2 0 0 2 2 2 1 PaRep2a protein PaRep2a PF07903.11 AAL63328.1 - 9.1e-64 212.8 1.9 1e-63 212.6 1.9 1.0 1 0 0 1 1 1 1 PaRep2a protein PaRep2b PF07775.11 AAL63330.1 - 7.5e-276 915.5 11.8 1e-275 915.1 11.8 1.2 1 0 0 1 1 1 1 PaRep2b protein HSR PF03172.13 AAL63330.1 - 0.049 13.8 0.1 14 5.9 0.0 3.2 3 0 0 3 3 3 0 HSR domain DUF1465 PF07323.12 AAL63330.1 - 0.4 10.5 2.8 0.23 11.3 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) SPOR PF05036.13 AAL63330.1 - 0.77 10.2 2.7 5.4 7.5 0.2 3.1 2 1 1 3 3 3 0 Sporulation related domain RNase_HII PF01351.18 AAL63331.1 - 1.2e-37 129.7 0.0 1.4e-37 129.5 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease HII PadR PF03551.14 AAL63332.1 - 8.2e-20 70.6 0.5 8.2e-20 70.6 0.5 1.7 2 0 0 2 2 2 1 Transcriptional regulator PadR-like family HTH_34 PF13601.6 AAL63332.1 - 0.00015 21.9 0.0 0.00042 20.4 0.0 1.8 1 1 0 1 1 1 1 Winged helix DNA-binding domain Replic_Relax PF13814.6 AAL63332.1 - 0.0055 16.8 0.0 0.007 16.5 0.0 1.2 1 0 0 1 1 1 1 Replication-relaxation Herpes_BBRF1 PF04793.12 AAL63332.1 - 0.018 14.1 0.1 0.025 13.6 0.1 1.2 1 0 0 1 1 1 0 BRRF1-like protein Cdc6_C PF09079.11 AAL63332.1 - 0.034 14.1 0.3 0.12 12.4 0.0 2.1 2 1 1 3 3 3 0 CDC6, C terminal winged helix domain DUF2513 PF10711.9 AAL63332.1 - 0.048 13.9 0.0 0.21 11.9 0.0 2.0 2 1 0 3 3 3 0 Hypothetical protein (DUF2513) HxlR PF01638.17 AAL63332.1 - 0.061 13.2 0.2 0.3 11.0 0.0 2.1 2 1 0 2 2 2 0 HxlR-like helix-turn-helix HTH_45 PF14947.6 AAL63332.1 - 0.1 12.6 0.1 0.33 11.0 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix DUF2635 PF10948.8 AAL63332.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2635) NAD_synthase PF02540.17 AAL63333.1 - 3.5e-75 252.2 0.0 4.3e-75 251.9 0.0 1.0 1 0 0 1 1 1 1 NAD synthase tRNA_Me_trans PF03054.16 AAL63333.1 - 5.3e-09 35.3 0.0 2.3e-05 23.3 0.0 2.3 2 0 0 2 2 2 2 tRNA methyl transferase Asn_synthase PF00733.21 AAL63333.1 - 0.041 13.5 0.0 0.044 13.5 0.0 1.1 1 0 0 1 1 1 0 Asparagine synthase QueC PF06508.13 AAL63333.1 - 0.073 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC ThiI PF02568.14 AAL63333.1 - 0.12 11.9 0.0 0.28 10.8 0.0 1.6 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) Thiolase_N PF00108.23 AAL63334.1 - 2.6e-80 269.6 0.0 3.1e-80 269.3 0.0 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 AAL63334.1 - 5.8e-41 139.0 0.0 4.1e-40 136.3 0.0 2.2 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 AAL63334.1 - 7.1e-07 29.1 1.9 4.7e-06 26.4 0.8 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 AAL63334.1 - 0.11 12.3 0.3 13 5.7 0.0 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ABC_tran PF00005.27 AAL63335.1 - 8.6e-35 120.2 0.0 1.4e-34 119.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAL63335.1 - 9.4e-11 42.1 0.2 2.5e-05 24.2 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAL63335.1 - 0.00011 21.8 0.1 0.12 11.8 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain CysA_C_terminal PF17850.1 AAL63335.1 - 0.0008 19.9 0.1 0.0024 18.4 0.1 1.9 1 0 0 1 1 1 1 CysA C-terminal regulatory domain AAA_29 PF13555.6 AAL63335.1 - 0.0012 18.6 0.0 0.0028 17.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AAL63335.1 - 0.0014 19.1 0.1 0.0026 18.2 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain OB_MalK PF17912.1 AAL63335.1 - 0.0014 19.4 0.3 0.0048 17.7 0.3 2.0 1 0 0 1 1 1 1 MalK OB fold domain AAA_23 PF13476.6 AAL63335.1 - 0.006 17.1 0.0 0.012 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AAL63335.1 - 0.01 16.1 0.9 0.043 14.1 0.1 2.0 2 0 0 2 2 2 0 AAA domain DLIC PF05783.11 AAL63335.1 - 0.014 14.2 0.0 0.022 13.6 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) RsgA_GTPase PF03193.16 AAL63335.1 - 0.035 14.0 0.0 0.074 13.0 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_24 PF13479.6 AAL63335.1 - 0.049 13.3 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AAL63335.1 - 0.052 13.3 0.1 0.12 12.0 0.0 1.5 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 AAL63335.1 - 0.054 13.7 0.1 0.44 10.8 0.1 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA PF00004.29 AAL63335.1 - 0.062 13.7 0.2 1.1 9.7 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TOBE_2 PF08402.10 AAL63335.1 - 0.08 13.1 0.0 0.24 11.6 0.0 1.8 1 0 0 1 1 1 0 TOBE domain AAA_25 PF13481.6 AAL63335.1 - 0.084 12.4 0.3 0.62 9.6 0.0 2.3 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 AAL63335.1 - 0.09 12.7 0.1 0.22 11.4 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 AAL63335.1 - 0.1 12.8 0.2 0.2 11.8 0.2 1.7 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 AAL63335.1 - 0.13 12.2 0.3 0.27 11.1 0.0 1.6 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.6 AAL63335.1 - 0.15 12.4 0.2 0.43 10.9 0.2 1.7 1 0 0 1 1 1 0 AAA domain UPF0160 PF03690.13 AAL63336.1 - 0.0078 15.9 0.0 0.02 14.6 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0160) Radical_SAM PF04055.21 AAL63336.1 - 0.059 13.7 0.0 7.6 6.9 0.0 2.8 2 1 0 2 2 2 0 Radical SAM superfamily Methyltransf_11 PF08241.12 AAL63337.1 - 9.3e-18 64.7 0.1 1.4e-17 64.1 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAL63337.1 - 2e-15 57.3 0.0 3e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAL63337.1 - 1.1e-09 38.9 0.0 1.8e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AAL63337.1 - 5.5e-07 29.2 0.0 7e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 AAL63337.1 - 1.2e-06 28.5 0.0 1.6e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAL63337.1 - 4.9e-06 26.4 0.0 5.5e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 AAL63337.1 - 0.00039 19.8 0.0 0.00042 19.7 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Met_10 PF02475.16 AAL63337.1 - 0.035 13.8 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein MetW PF07021.12 AAL63337.1 - 0.037 13.6 0.0 0.12 11.9 0.0 1.9 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW FtsJ PF01728.19 AAL63337.1 - 0.053 13.6 0.0 0.091 12.9 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.14 AAL63337.1 - 0.1 12.1 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain PLDc_2 PF13091.6 AAL63338.1 - 2e-32 111.8 0.0 2.8e-23 82.2 0.0 2.1 2 0 0 2 2 2 2 PLD-like domain Regulator_TrmB PF11495.8 AAL63338.1 - 0.0002 20.6 0.0 0.00033 19.9 0.0 1.4 1 0 0 1 1 1 1 Archaeal transcriptional regulator TrmB PLDc PF00614.22 AAL63338.1 - 0.0029 17.7 6.6 0.34 11.2 0.4 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PP_kinase_C_1 PF17941.1 AAL63338.1 - 0.011 15.2 0.1 0.022 14.3 0.1 1.5 1 0 0 1 1 1 0 Polyphosphate kinase C-terminal domain 1 FAM83 PF07894.12 AAL63338.1 - 0.14 11.7 0.1 0.26 10.8 0.1 1.4 1 0 0 1 1 1 0 FAM83 A-H PQQ_3 PF13570.6 AAL63338.1 - 0.17 12.4 1.0 10 6.8 0.4 2.8 2 0 0 2 2 2 0 PQQ-like domain MarR_2 PF12802.7 AAL63339.1 - 1.9e-07 30.8 0.0 3.3e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 MarR family TrmB PF01978.19 AAL63339.1 - 5.6e-05 22.9 0.0 0.0001 22.1 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR PF01047.22 AAL63339.1 - 0.00047 20.0 0.0 0.0012 18.7 0.0 1.7 1 0 0 1 1 1 1 MarR family HTH_45 PF14947.6 AAL63339.1 - 0.0016 18.3 0.0 0.0028 17.6 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DUF4364 PF14277.6 AAL63339.1 - 0.0028 17.4 0.0 0.0033 17.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) HTH_27 PF13463.6 AAL63339.1 - 0.0029 18.1 0.0 0.0048 17.4 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain DotU PF09850.9 AAL63339.1 - 0.0086 15.8 0.1 0.012 15.3 0.1 1.2 1 0 0 1 1 1 1 Type VI secretion system protein DotU HTH_24 PF13412.6 AAL63339.1 - 0.0087 15.6 0.0 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding DUF505 PF04458.12 AAL63339.1 - 0.0094 14.4 0.3 0.0098 14.3 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF505) Rrf2 PF02082.20 AAL63339.1 - 0.02 15.2 0.1 0.044 14.1 0.0 1.6 2 0 0 2 2 2 0 Transcriptional regulator HTH_12 PF08461.10 AAL63339.1 - 0.029 14.3 0.7 0.07 13.1 0.1 1.9 2 0 0 2 2 2 0 Ribonuclease R winged-helix domain DUF2250 PF10007.9 AAL63339.1 - 0.037 14.1 0.1 0.33 11.1 0.0 2.1 1 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) LexA_DNA_bind PF01726.16 AAL63339.1 - 0.065 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 LexA DNA binding domain Replic_Relax PF13814.6 AAL63339.1 - 0.074 13.1 0.0 0.094 12.8 0.0 1.1 1 0 0 1 1 1 0 Replication-relaxation DeoC PF01791.9 AAL63340.1 - 2.7e-06 27.2 0.1 3.3e-06 26.9 0.1 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase Radical_SAM PF04055.21 AAL63340.1 - 0.15 12.4 0.0 0.56 10.6 0.0 2.0 1 1 0 1 1 1 0 Radical SAM superfamily Acylphosphatase PF00708.18 AAL63341.1 - 1.2e-27 96.1 0.3 1.3e-27 96.0 0.3 1.0 1 0 0 1 1 1 1 Acylphosphatase DUF1122 PF06557.11 AAL63342.1 - 1.1e-37 129.2 0.1 1.4e-37 128.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1122) UCR_14kD PF02271.16 AAL63343.1 - 0.075 13.0 0.0 0.087 12.8 0.0 1.2 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit DUF4190 PF13828.6 AAL63344.1 - 0.026 14.3 5.6 0.35 10.7 5.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4190) DUF4282 PF14110.6 AAL63344.1 - 0.065 14.0 1.9 0.082 13.7 1.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) DUF308 PF03729.13 AAL63344.1 - 0.12 12.8 5.6 0.2 12.0 5.5 1.4 1 1 0 1 1 1 0 Short repeat of unknown function (DUF308) RimK PF08443.11 AAL63346.1 - 6.9e-41 139.9 0.0 8.7e-41 139.6 0.0 1.1 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 AAL63346.1 - 2.6e-14 53.6 0.0 3.6e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 ATP-grasp domain GSH-S_ATP PF02955.16 AAL63346.1 - 4.7e-12 45.7 0.0 6.6e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain CPSase_L_D2 PF02786.17 AAL63346.1 - 1.4e-09 37.7 0.0 4.1e-09 36.2 0.0 1.8 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.13 AAL63346.1 - 5.1e-07 29.4 0.0 1.3e-05 24.8 0.0 2.1 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 AAL63346.1 - 2.3e-05 24.0 0.0 3.7e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 AAL63346.1 - 2.9e-05 23.5 0.0 0.053 12.8 0.0 2.4 1 1 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_5 PF13549.6 AAL63346.1 - 0.023 14.2 0.0 0.21 11.0 0.0 2.1 2 0 0 2 2 2 0 ATP-grasp domain TTL PF03133.15 AAL63346.1 - 0.053 12.6 0.0 0.18 10.9 0.0 1.7 2 0 0 2 2 2 0 Tubulin-tyrosine ligase family ATP-grasp_4 PF13535.6 AAL63346.1 - 0.054 13.1 0.0 0.093 12.3 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_YheCD PF14398.6 AAL63346.1 - 0.062 12.5 0.0 1.3 8.2 0.0 2.6 1 1 0 1 1 1 0 YheC/D like ATP-grasp DUF2203 PF09969.9 AAL63347.1 - 1.9e-22 80.3 0.3 2.2e-20 73.6 0.3 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2203) Gag_p15 PF08723.10 AAL63347.1 - 0.089 13.0 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Gag protein p15 SWIM PF04434.17 AAL63348.1 - 1.2e-07 31.2 0.3 2.6e-07 30.2 0.3 1.6 1 0 0 1 1 1 1 SWIM zinc finger IF-2B PF01008.17 AAL63349.1 - 6.5e-06 25.6 0.0 0.00015 21.0 0.0 2.0 1 1 0 1 1 1 1 Initiation factor 2 subunit family ABC_tran PF00005.27 AAL63350.1 - 4.8e-22 79.0 0.0 6.9e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAL63350.1 - 1.3e-10 41.6 0.7 0.0001 22.2 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAL63350.1 - 1.3e-06 28.0 0.0 0.003 17.0 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AAL63350.1 - 1.7e-06 28.7 0.0 2.7e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAL63350.1 - 6.7e-05 23.3 0.1 0.00011 22.7 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 AAL63350.1 - 0.0001 22.1 0.1 0.039 13.7 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_27 PF13514.6 AAL63350.1 - 0.00012 21.8 0.0 0.00025 20.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAL63350.1 - 0.00012 21.7 0.0 0.00021 21.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SSE PF00437.20 AAL63350.1 - 0.00079 18.6 0.0 0.0013 17.9 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein NTPase_1 PF03266.15 AAL63350.1 - 0.0086 16.0 0.1 0.041 13.8 0.0 2.0 2 0 0 2 2 2 1 NTPase AAA_30 PF13604.6 AAL63350.1 - 0.021 14.6 0.0 0.043 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AAL63350.1 - 0.023 15.0 0.1 0.083 13.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AAL63350.1 - 0.045 13.3 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 AAL63350.1 - 0.059 13.1 0.0 0.081 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 AAL63350.1 - 0.064 12.5 0.0 0.13 11.5 0.0 1.5 1 1 0 1 1 1 0 Zeta toxin RsgA_GTPase PF03193.16 AAL63350.1 - 0.089 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase TIP49 PF06068.13 AAL63350.1 - 0.096 11.9 0.1 0.64 9.2 0.0 2.1 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_33 PF13671.6 AAL63350.1 - 0.096 12.8 0.0 2.7 8.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 AAL63350.1 - 0.11 11.3 0.2 3.5 6.3 0.1 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA PF00004.29 AAL63350.1 - 0.12 12.9 0.1 0.46 10.9 0.0 2.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 AAL63350.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 AAL63350.1 - 0.14 11.8 0.0 0.8 9.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 AAL63350.1 - 0.19 12.1 0.1 0.81 10.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 AAL63350.1 - 0.23 11.1 0.0 0.88 9.2 0.1 1.7 2 0 0 2 2 2 0 AAA ATPase domain ABC-3 PF00950.17 AAL63351.1 - 1.4e-17 64.1 26.7 1.9e-17 63.6 26.7 1.2 1 0 0 1 1 1 1 ABC 3 transport family FecCD PF01032.18 AAL63351.1 - 3.6e-08 32.8 26.6 3.6e-08 32.8 26.6 1.9 1 1 1 2 2 2 1 FecCD transport family GAS PF13851.6 AAL63352.1 - 4e-08 32.8 63.2 5e-05 22.7 20.4 2.7 1 1 2 3 3 3 3 Growth-arrest specific micro-tubule binding Yuri_gagarin PF15934.5 AAL63352.1 - 1.1e-07 31.9 15.8 1.7e-07 31.4 15.8 1.2 1 0 0 1 1 1 1 Yuri gagarin TMF_DNA_bd PF12329.8 AAL63352.1 - 2.7e-07 30.5 30.5 0.002 18.1 4.6 3.9 1 1 4 5 5 5 3 TATA element modulatory factor 1 DNA binding Spc7 PF08317.11 AAL63352.1 - 3.8e-07 29.3 29.4 0.00011 21.3 17.9 2.4 1 1 1 2 2 2 2 Spc7 kinetochore protein APG6_N PF17675.1 AAL63352.1 - 4.7e-07 30.4 40.1 0.0061 17.1 8.5 2.9 1 1 1 2 2 2 2 Apg6 coiled-coil region Prefoldin_2 PF01920.20 AAL63352.1 - 9.8e-07 28.7 23.8 0.00084 19.3 0.2 4.2 2 1 1 3 3 3 1 Prefoldin subunit DUF3584 PF12128.8 AAL63352.1 - 4.1e-06 24.7 22.2 5.4e-06 24.3 22.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) ATG16 PF08614.11 AAL63352.1 - 7.1e-06 26.4 35.9 0.00093 19.5 21.4 2.2 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) IFT57 PF10498.9 AAL63352.1 - 9.2e-06 24.9 23.3 0.0066 15.5 8.3 2.8 1 1 1 2 2 2 2 Intra-flagellar transport protein 57 EzrA PF06160.12 AAL63352.1 - 9.4e-06 24.1 23.3 3.4e-05 22.3 23.3 1.8 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA Tektin PF03148.14 AAL63352.1 - 1.2e-05 24.3 26.0 6e-05 22.0 9.0 2.1 1 1 1 2 2 2 2 Tektin family Myosin_tail_1 PF01576.19 AAL63352.1 - 1.4e-05 23.2 25.2 2.3e-05 22.4 23.9 1.9 1 1 1 2 2 2 1 Myosin tail XhlA PF10779.9 AAL63352.1 - 2e-05 24.7 13.5 0.0024 18.1 1.5 4.1 2 1 1 4 4 4 1 Haemolysin XhlA DUF3450 PF11932.8 AAL63352.1 - 2.3e-05 23.8 38.9 0.0023 17.3 15.6 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF3450) Rootletin PF15035.6 AAL63352.1 - 2.9e-05 24.2 30.6 0.0044 17.1 16.6 2.1 1 1 1 2 2 2 2 Ciliary rootlet component, centrosome cohesion Rab5-bind PF09311.11 AAL63352.1 - 3.8e-05 23.3 21.0 0.0051 16.2 11.6 2.3 1 1 1 2 2 2 2 Rabaptin-like protein DUF1664 PF07889.12 AAL63352.1 - 3.8e-05 23.7 12.7 0.21 11.6 2.8 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF1664) DUF4201 PF13870.6 AAL63352.1 - 4e-05 23.4 26.3 0.00084 19.1 15.8 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4201) MscS_porin PF12795.7 AAL63352.1 - 4.7e-05 23.1 46.1 0.0021 17.6 32.2 2.1 1 1 1 2 2 2 2 Mechanosensitive ion channel porin domain CENP-F_leu_zip PF10473.9 AAL63352.1 - 5.2e-05 23.3 26.7 0.00036 20.6 15.1 2.7 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin PF02996.17 AAL63352.1 - 5.7e-05 23.0 30.8 0.013 15.4 3.7 4.8 2 1 3 5 5 5 2 Prefoldin subunit DUF5082 PF16888.5 AAL63352.1 - 6.3e-05 23.3 22.2 0.0054 17.0 1.1 3.7 2 1 1 3 3 3 2 Domain of unknown function (DUF5082) SHE3 PF17078.5 AAL63352.1 - 6.5e-05 22.7 25.4 0.00045 20.0 25.4 2.2 1 1 0 1 1 1 1 SWI5-dependent HO expression protein 3 DivIC PF04977.15 AAL63352.1 - 8.2e-05 22.3 37.3 0.0058 16.4 1.8 5.2 1 1 3 4 4 4 1 Septum formation initiator FPP PF05911.11 AAL63352.1 - 9.4e-05 20.8 25.1 0.00019 19.8 21.2 2.0 1 1 1 2 2 2 1 Filament-like plant protein, long coiled-coil DUF4349 PF14257.6 AAL63352.1 - 0.0001 21.8 25.6 0.04 13.3 5.5 2.8 1 1 2 3 3 3 2 Domain of unknown function (DUF4349) Fez1 PF06818.15 AAL63352.1 - 0.00011 22.7 22.0 0.0015 19.0 16.6 2.4 1 1 1 2 2 2 1 Fez1 Filament PF00038.21 AAL63352.1 - 0.00013 21.7 29.1 0.00084 19.0 15.2 2.2 1 1 0 1 1 1 1 Intermediate filament protein Nup54 PF13874.6 AAL63352.1 - 0.00013 22.1 25.6 0.00042 20.4 8.5 2.8 1 1 1 2 2 2 1 Nucleoporin complex subunit 54 BLOC1_2 PF10046.9 AAL63352.1 - 0.00017 21.8 25.0 0.0051 17.1 4.5 3.8 1 1 3 4 4 4 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_II PF06009.12 AAL63352.1 - 0.00026 21.0 18.5 0.0065 16.5 5.0 3.0 1 1 2 3 3 3 1 Laminin Domain II DUF948 PF06103.11 AAL63352.1 - 0.00027 21.1 6.3 0.43 10.9 0.0 3.8 2 1 1 3 3 3 1 Bacterial protein of unknown function (DUF948) Seryl_tRNA_N PF02403.22 AAL63352.1 - 0.00028 21.1 24.9 0.035 14.3 8.3 3.4 1 1 3 4 4 4 3 Seryl-tRNA synthetase N-terminal domain Fib_alpha PF08702.10 AAL63352.1 - 0.00029 21.0 15.7 0.032 14.4 0.5 2.8 2 1 1 3 3 3 3 Fibrinogen alpha/beta chain family MAD PF05557.13 AAL63352.1 - 0.00037 19.0 22.6 0.00052 18.5 22.6 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein AAA_13 PF13166.6 AAL63352.1 - 0.00038 19.3 20.8 0.0036 16.0 2.7 2.3 1 1 1 2 2 2 2 AAA domain TPR_MLP1_2 PF07926.12 AAL63352.1 - 0.00042 20.4 39.4 0.0097 16.0 23.6 3.0 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.12 AAL63352.1 - 0.00042 20.4 18.6 0.067 13.2 2.6 3.1 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Atg14 PF10186.9 AAL63352.1 - 0.00043 19.5 26.6 0.033 13.3 10.7 2.2 1 1 1 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 Spectrin PF00435.21 AAL63352.1 - 0.00045 20.7 25.0 0.0098 16.4 7.4 3.0 1 1 0 2 2 2 1 Spectrin repeat Jnk-SapK_ap_N PF09744.9 AAL63352.1 - 0.00045 20.5 27.3 31 4.8 26.3 2.8 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 KxDL PF10241.9 AAL63352.1 - 0.00056 20.1 19.3 0.2 12.0 1.6 3.6 2 1 1 3 3 3 2 Uncharacterized conserved protein COG5 PF10392.9 AAL63352.1 - 0.00059 20.0 17.4 0.015 15.5 1.3 3.0 1 1 2 3 3 3 2 Golgi transport complex subunit 5 Macoilin PF09726.9 AAL63352.1 - 0.0007 18.3 27.4 0.002 16.8 15.5 2.0 1 1 0 2 2 2 1 Macoilin family ADIP PF11559.8 AAL63352.1 - 0.00073 19.6 32.6 0.0047 17.0 6.6 3.4 1 1 3 4 4 4 2 Afadin- and alpha -actinin-Binding ABC_tran_CTD PF16326.5 AAL63352.1 - 0.00077 19.7 39.2 0.15 12.3 4.0 4.8 1 1 2 3 3 2 1 ABC transporter C-terminal domain BRE1 PF08647.11 AAL63352.1 - 0.00092 19.2 29.7 0.13 12.3 4.2 3.2 2 1 1 3 3 3 2 BRE1 E3 ubiquitin ligase DUF4795 PF16043.5 AAL63352.1 - 0.00095 18.8 22.7 0.082 12.5 17.2 3.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4795) DUF812 PF05667.11 AAL63352.1 - 0.00096 18.2 24.0 0.094 11.6 2.8 2.9 1 1 2 3 3 3 3 Protein of unknown function (DUF812) Taxilin PF09728.9 AAL63352.1 - 0.00097 18.4 23.7 0.023 13.9 11.5 2.1 1 1 1 2 2 2 2 Myosin-like coiled-coil protein T3SSipB PF16535.5 AAL63352.1 - 0.0012 19.3 18.3 0.0012 19.3 18.3 2.3 1 1 1 2 2 2 1 Type III cell invasion protein SipB HMMR_N PF15905.5 AAL63352.1 - 0.0013 18.3 26.3 0.0069 15.9 15.0 2.0 1 1 1 2 2 2 1 Hyaluronan mediated motility receptor N-terminal HAUS-augmin3 PF14932.6 AAL63352.1 - 0.0015 18.2 32.8 0.0082 15.7 21.2 2.3 1 1 1 2 2 2 1 HAUS augmin-like complex subunit 3 UPF0242 PF06785.11 AAL63352.1 - 0.0015 18.7 31.3 0.04 14.0 3.5 3.1 1 1 2 3 3 3 1 Uncharacterised protein family (UPF0242) N-terminus DHR10 PF18595.1 AAL63352.1 - 0.0017 18.4 37.6 0.12 12.5 5.8 3.6 1 1 2 3 3 3 2 Designed helical repeat protein 10 domain PspA_IM30 PF04012.12 AAL63352.1 - 0.0017 17.9 37.7 0.021 14.4 5.7 2.9 1 1 1 2 2 2 1 PspA/IM30 family HAP1_N PF04849.13 AAL63352.1 - 0.0018 17.5 27.4 0.075 12.2 10.9 2.1 1 1 0 2 2 2 2 HAP1 N-terminal conserved region DUF4407 PF14362.6 AAL63352.1 - 0.0019 17.6 32.8 0.034 13.5 25.7 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4407) Troponin PF00992.20 AAL63352.1 - 0.0019 18.5 16.8 0.24 11.7 0.2 3.2 2 1 1 3 3 3 2 Troponin FH2 PF02181.23 AAL63352.1 - 0.002 17.3 17.7 0.011 14.9 3.1 3.3 1 1 1 3 3 3 1 Formin Homology 2 Domain YabA PF06156.13 AAL63352.1 - 0.0024 18.5 19.4 0.19 12.4 3.6 3.3 1 1 3 4 4 4 1 Initiation control protein YabA phiKZ_IP PF12699.7 AAL63352.1 - 0.0025 17.0 4.7 0.039 13.1 0.1 2.6 2 1 1 3 3 2 1 phiKZ-like phage internal head proteins Lebercilin PF15619.6 AAL63352.1 - 0.0027 17.4 31.4 0.029 14.0 31.5 2.3 1 1 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease HOOK PF05622.12 AAL63352.1 - 0.0029 15.8 27.3 0.025 12.7 16.6 2.0 1 1 1 2 2 2 2 HOOK protein ZapB PF06005.12 AAL63352.1 - 0.0029 18.0 38.7 0.21 12.0 14.2 4.0 1 1 2 3 3 3 1 Cell division protein ZapB DUF2730 PF10805.8 AAL63352.1 - 0.003 17.6 11.9 0.2 11.8 2.8 3.8 1 1 3 4 4 4 2 Protein of unknown function (DUF2730) TACC_C PF05010.14 AAL63352.1 - 0.0033 17.3 24.0 0.61 9.8 24.0 2.3 1 1 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal CENP-Q PF13094.6 AAL63352.1 - 0.0038 17.4 36.3 0.029 14.6 8.6 3.4 1 1 2 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit Mod_r PF07200.13 AAL63352.1 - 0.0038 17.3 34.6 0.99 9.5 11.3 3.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF713 PF05218.14 AAL63352.1 - 0.0041 16.9 5.4 0.015 15.0 1.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF713) Fmp27_WPPW PF10359.9 AAL63352.1 - 0.0045 15.9 13.3 6.1 5.6 13.3 2.3 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain CLZ PF16526.5 AAL63352.1 - 0.0049 17.2 1.1 0.0049 17.2 1.1 4.4 2 1 3 5 5 4 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels bZIP_2 PF07716.15 AAL63352.1 - 0.0053 16.8 0.8 0.0053 16.8 0.8 4.8 3 2 2 5 5 4 1 Basic region leucine zipper CENP-H PF05837.12 AAL63352.1 - 0.0054 17.1 28.7 0.013 15.8 3.8 3.1 1 1 1 2 2 2 1 Centromere protein H (CENP-H) NPV_P10 PF05531.12 AAL63352.1 - 0.0062 17.0 19.0 0.26 11.8 4.8 3.6 1 1 2 3 3 3 1 Nucleopolyhedrovirus P10 protein HSBP1 PF06825.12 AAL63352.1 - 0.0062 16.4 1.3 0.2 11.6 0.0 3.2 3 1 0 3 3 2 1 Heat shock factor binding protein 1 Phage_GP20 PF06810.11 AAL63352.1 - 0.0064 16.3 24.8 0.072 12.9 8.0 3.6 1 1 3 4 4 4 2 Phage minor structural protein GP20 WEMBL PF05701.11 AAL63352.1 - 0.0074 15.0 21.0 0.011 14.5 21.0 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light WXG100 PF06013.12 AAL63352.1 - 0.0074 16.5 27.2 0.08 13.2 0.9 4.0 2 1 2 4 4 4 1 Proteins of 100 residues with WXG HIP1_clath_bdg PF16515.5 AAL63352.1 - 0.0076 16.8 3.3 0.0076 16.8 3.3 3.1 2 1 1 3 3 3 1 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4600 PF15372.6 AAL63352.1 - 0.0091 16.4 21.6 0.083 13.3 10.3 2.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4600) Tropomyosin PF00261.20 AAL63352.1 - 0.0099 15.3 26.6 0.22 10.9 10.0 2.4 1 1 1 2 2 2 2 Tropomyosin FapA PF03961.13 AAL63352.1 - 0.011 14.4 19.5 0.12 11.0 10.0 2.7 1 1 1 2 2 2 0 Flagellar Assembly Protein A TMF_TATA_bd PF12325.8 AAL63352.1 - 0.012 15.8 27.4 0.77 10.0 5.1 3.2 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding Spc24 PF08286.11 AAL63352.1 - 0.014 15.6 30.6 0.17 12.1 3.9 4.8 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 HrpB7 PF09486.10 AAL63352.1 - 0.017 15.5 33.2 0.41 11.0 2.8 3.4 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Lectin_N PF03954.14 AAL63352.1 - 0.018 14.8 1.4 0.018 14.8 1.4 3.3 1 1 1 3 3 3 0 Hepatic lectin, N-terminal domain FliD_C PF07195.12 AAL63352.1 - 0.022 14.2 17.5 0.062 12.7 0.5 3.3 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus FlaC_arch PF05377.11 AAL63352.1 - 0.023 15.1 13.5 0.59 10.6 0.9 4.8 1 1 3 5 5 5 0 Flagella accessory protein C (FlaC) DUF4763 PF15960.5 AAL63352.1 - 0.023 14.0 27.7 0.67 9.2 15.7 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) Cep57_MT_bd PF06657.13 AAL63352.1 - 0.023 15.1 23.3 1.5 9.4 4.5 5.0 2 1 3 5 5 5 0 Centrosome microtubule-binding domain of Cep57 DUF724 PF05266.14 AAL63352.1 - 0.024 14.5 17.0 2 8.2 9.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Prominin PF05478.11 AAL63352.1 - 0.026 12.5 9.2 0.039 11.9 9.2 1.3 1 0 0 1 1 1 0 Prominin Tup_N PF08581.10 AAL63352.1 - 0.027 14.8 20.3 0.15 12.4 1.0 4.0 2 1 1 3 3 3 0 Tup N-terminal Golgin_A5 PF09787.9 AAL63352.1 - 0.028 13.9 25.8 0.13 11.7 18.9 2.6 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF4472 PF14739.6 AAL63352.1 - 0.028 15.1 26.2 0.047 14.4 4.2 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) THOC7 PF05615.13 AAL63352.1 - 0.031 14.6 31.1 0.62 10.3 2.6 3.8 1 1 3 4 4 4 0 Tho complex subunit 7 Tropomyosin_1 PF12718.7 AAL63352.1 - 0.034 14.3 28.4 0.18 11.9 17.4 2.5 1 1 1 2 2 2 0 Tropomyosin like Laminin_I PF06008.14 AAL63352.1 - 0.034 13.8 25.0 0.029 14.1 14.4 2.2 1 1 1 2 2 2 0 Laminin Domain I FAM76 PF16046.5 AAL63352.1 - 0.038 13.4 17.5 0.047 13.0 9.2 2.1 1 1 1 2 2 2 0 FAM76 protein FliJ PF02050.16 AAL63352.1 - 0.039 14.2 40.8 0.44 10.8 11.7 3.1 1 1 3 4 4 4 0 Flagellar FliJ protein JIP_LZII PF16471.5 AAL63352.1 - 0.041 14.1 16.4 2.4 8.4 0.2 4.4 2 1 3 5 5 5 0 JNK-interacting protein leucine zipper II FUSC PF04632.12 AAL63352.1 - 0.048 12.2 22.6 0.16 10.5 22.6 1.7 1 1 0 1 1 1 0 Fusaric acid resistance protein family Sec34 PF04136.15 AAL63352.1 - 0.049 13.5 19.4 0.38 10.6 5.2 3.4 1 1 2 3 3 3 0 Sec34-like family FlxA PF14282.6 AAL63352.1 - 0.05 13.6 34.9 0.24 11.4 8.3 3.9 1 1 3 4 4 4 0 FlxA-like protein PKcGMP_CC PF16808.5 AAL63352.1 - 0.055 13.3 0.2 0.055 13.3 0.2 4.0 3 1 1 4 4 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase OmpH PF03938.14 AAL63352.1 - 0.056 13.8 39.3 11 6.3 16.7 2.9 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) GrpE PF01025.19 AAL63352.1 - 0.064 12.9 27.6 0.14 11.8 3.6 3.8 1 1 2 3 3 2 0 GrpE DUF4140 PF13600.6 AAL63352.1 - 0.079 13.4 29.9 0.092 13.2 0.6 4.6 3 1 1 4 4 2 0 N-terminal domain of unknown function (DUF4140) DUF4686 PF15742.5 AAL63352.1 - 0.081 12.1 30.7 0.17 11.0 30.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4686) TSKS PF15358.6 AAL63352.1 - 0.081 11.3 12.9 0.47 8.8 12.8 1.7 1 1 0 1 1 1 0 Testis-specific serine kinase substrate Vps52 PF04129.12 AAL63352.1 - 0.091 11.5 9.9 0.059 12.1 5.4 2.0 1 1 1 2 2 2 0 Vps52 / Sac2 family Occludin_ELL PF07303.13 AAL63352.1 - 0.091 13.5 20.7 0.36 11.6 9.1 3.6 1 1 2 3 3 3 0 Occludin homology domain HemX PF04375.14 AAL63352.1 - 0.095 12.0 33.0 0.43 9.8 4.3 2.9 1 1 1 2 2 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase SlyX PF04102.12 AAL63352.1 - 0.095 13.3 34.9 0.32 11.6 5.0 4.5 1 1 3 4 4 2 0 SlyX DUF4988 PF16378.5 AAL63352.1 - 0.096 12.3 7.0 0.72 9.5 0.7 4.1 4 1 0 4 4 3 0 Domain of unknown function TolA_bind_tri PF16331.5 AAL63352.1 - 0.097 12.8 35.9 1 9.5 8.6 4.4 1 1 4 5 5 5 0 TolA binding protein trimerisation SKA1 PF07160.12 AAL63352.1 - 0.099 12.5 17.1 0.13 12.1 3.2 2.2 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF2959 PF11172.8 AAL63352.1 - 0.1 12.8 20.3 0.3 11.2 8.1 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF2959) Lip_prot_lig_C PF10437.9 AAL63352.1 - 0.12 12.4 3.6 8 6.5 0.1 3.5 1 1 1 3 3 3 0 Bacterial lipoate protein ligase C-terminus Syntaxin-6_N PF09177.11 AAL63352.1 - 0.12 13.0 18.5 5.9 7.5 1.4 3.9 1 1 1 2 2 1 0 Syntaxin 6, N-terminal Filo_VP35 PF02097.15 AAL63352.1 - 0.12 11.4 3.7 0.82 8.7 0.4 2.5 1 1 1 2 2 2 0 Filoviridae VP35 DUF4200 PF13863.6 AAL63352.1 - 0.13 12.7 28.4 1.2 9.6 3.0 3.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4200) DUF4315 PF14193.6 AAL63352.1 - 0.13 12.3 19.3 0.53 10.3 6.1 4.5 1 1 3 4 4 3 0 Domain of unknown function (DUF4315) Osmo_CC PF08946.10 AAL63352.1 - 0.13 12.5 0.4 0.13 12.5 0.4 3.4 3 1 0 3 3 2 0 Osmosensory transporter coiled coil PI3K_P85_iSH2 PF16454.5 AAL63352.1 - 0.14 11.7 25.1 2.7 7.6 1.9 4.2 1 1 2 4 4 4 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF2046 PF09755.9 AAL63352.1 - 0.17 11.1 22.9 7.9 5.6 22.9 2.6 1 1 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) She9_MDM33 PF05546.11 AAL63352.1 - 0.17 11.7 19.1 0.24 11.2 11.4 2.5 1 1 1 2 2 2 0 She9 / Mdm33 family Sec2p PF06428.11 AAL63352.1 - 0.18 11.8 30.5 0.22 11.5 4.8 4.2 1 1 2 4 4 4 0 GDP/GTP exchange factor Sec2p DUF16 PF01519.16 AAL63352.1 - 0.18 12.3 17.5 2 8.9 2.7 2.9 1 1 1 2 2 1 0 Protein of unknown function DUF16 CdvA PF18822.1 AAL63352.1 - 0.18 11.6 22.4 1.9 8.3 9.0 3.5 1 1 1 2 2 2 0 CdvA-like coiled-coil domain DegS PF05384.11 AAL63352.1 - 0.18 11.3 24.1 0.13 11.7 6.7 3.1 1 1 1 3 3 3 0 Sensor protein DegS Med9 PF07544.13 AAL63352.1 - 0.18 11.9 21.3 13 5.9 7.9 3.3 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 TMPIT PF07851.13 AAL63352.1 - 0.18 11.0 19.2 2.9 7.0 5.3 2.9 1 1 1 2 2 2 0 TMPIT-like protein Exonuc_VII_L PF02601.15 AAL63352.1 - 0.21 11.1 26.7 58 3.1 26.9 2.1 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF4618 PF15397.6 AAL63352.1 - 0.21 10.9 20.2 0.29 10.5 17.3 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) CCDC144C PF14915.6 AAL63352.1 - 0.23 10.5 25.5 0.83 8.7 25.5 1.7 1 1 0 1 1 1 0 CCDC144C protein coiled-coil region CALCOCO1 PF07888.11 AAL63352.1 - 0.25 10.2 28.3 1.1 8.1 28.4 1.8 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like CHD5 PF04420.14 AAL63352.1 - 0.26 11.1 20.4 0.2 11.5 1.2 3.5 1 1 2 3 3 3 0 CHD5-like protein Sulfatase_C PF14707.6 AAL63352.1 - 0.3 11.8 10.0 7.6 7.3 1.1 3.6 1 1 3 4 4 3 0 C-terminal region of aryl-sulfatase Snapin_Pallidin PF14712.6 AAL63352.1 - 0.31 11.5 29.0 2.4 8.6 7.9 3.8 1 1 2 3 3 3 0 Snapin/Pallidin Scaffolding_pro PF11418.8 AAL63352.1 - 0.33 11.5 9.6 17 6.1 0.2 3.5 1 1 3 4 4 3 0 Phi29 scaffolding protein Uso1_p115_C PF04871.13 AAL63352.1 - 0.35 11.2 34.8 7.8 6.9 9.4 3.1 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region KASH_CCD PF14662.6 AAL63352.1 - 0.37 10.6 26.9 0.37 10.6 23.4 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Syntaxin PF00804.25 AAL63352.1 - 0.39 10.3 16.6 1.6 8.4 9.2 2.2 1 1 1 2 2 2 0 Syntaxin PRKG1_interact PF15898.5 AAL63352.1 - 0.4 11.6 27.1 0.59 11.1 8.5 3.6 1 1 2 3 3 2 0 cGMP-dependent protein kinase interacting domain DUF2203 PF09969.9 AAL63352.1 - 0.4 11.4 20.1 1.1 10.0 1.9 3.2 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) MMPL PF03176.15 AAL63352.1 - 0.44 9.4 5.4 0.26 10.2 3.0 1.8 1 1 1 2 2 1 0 MMPL family Cortex-I_coil PF09304.10 AAL63352.1 - 0.44 10.8 25.1 6.1 7.1 6.8 3.3 1 1 2 3 3 3 0 Cortexillin I, coiled coil DASH_Dam1 PF08653.10 AAL63352.1 - 0.44 10.4 7.6 13 5.7 0.1 4.4 2 1 2 4 4 4 0 DASH complex subunit Dam1 APG17 PF04108.12 AAL63352.1 - 0.48 9.5 21.8 0.68 9.0 5.3 2.1 1 1 1 2 2 2 0 Autophagy protein Apg17 Ax_dynein_light PF10211.9 AAL63352.1 - 0.57 10.1 24.0 3.8 7.4 5.1 3.4 1 1 2 3 3 3 0 Axonemal dynein light chain Med8 PF10232.9 AAL63352.1 - 0.63 9.6 10.4 0.93 9.0 1.8 2.3 1 1 1 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 Swi5 PF07061.11 AAL63352.1 - 0.65 10.1 27.5 0.41 10.8 3.3 4.7 1 1 2 4 4 4 0 Swi5 Cluap1 PF10234.9 AAL63352.1 - 0.65 9.3 25.6 2.2 7.6 15.2 2.4 1 1 1 2 2 2 0 Clusterin-associated protein-1 CorA PF01544.18 AAL63352.1 - 0.67 9.2 21.5 0.35 10.1 10.9 2.6 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein AATF-Che1 PF13339.6 AAL63352.1 - 0.81 10.4 18.2 7e+02 0.8 18.2 2.6 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor MbeD_MobD PF04899.12 AAL63352.1 - 0.81 9.8 22.6 0.45 10.7 0.2 4.1 2 1 2 4 4 4 0 MbeD/MobD like BST2 PF16716.5 AAL63352.1 - 0.82 10.3 28.6 2 9.0 4.2 3.4 1 1 1 3 3 3 0 Bone marrow stromal antigen 2 Vip3A_N PF12495.8 AAL63352.1 - 0.87 9.5 5.7 1.3 8.9 4.3 2.0 2 1 0 2 2 1 0 Vegetative insecticide protein 3A N terminal NleF_casp_inhib PF16809.5 AAL63352.1 - 0.88 9.5 6.4 0.64 9.9 0.7 2.6 1 1 2 3 3 2 0 NleF caspase inhibitor TSC22 PF01166.18 AAL63352.1 - 0.89 9.9 10.0 0.7 10.2 0.5 3.8 1 1 0 3 3 2 0 TSC-22/dip/bun family bZIP_1 PF00170.21 AAL63352.1 - 0.89 9.7 26.4 0.24 11.5 1.3 4.7 2 2 3 5 5 5 0 bZIP transcription factor Lipoprotein_20 PF13942.6 AAL63352.1 - 0.94 9.4 23.7 0.17 11.8 5.7 3.2 1 1 2 3 3 3 0 YfhG lipoprotein SLATT_5 PF18160.1 AAL63352.1 - 0.95 8.8 12.3 0.045 13.1 6.0 2.1 2 1 0 2 2 1 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF3552 PF12072.8 AAL63352.1 - 0.96 8.8 28.2 1.2 8.5 16.8 2.5 1 1 1 2 2 1 0 Domain of unknown function (DUF3552) HAUS5 PF14817.6 AAL63352.1 - 1 8.1 25.3 0.6 8.8 13.7 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 5 COG2 PF06148.11 AAL63352.1 - 1.1 9.4 17.6 1.8 8.7 1.2 3.3 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Noelin-1 PF12308.8 AAL63352.1 - 1.1 9.3 12.2 0.56 10.2 1.3 3.1 1 1 2 3 3 3 0 Neurogenesis glycoprotein MPS2 PF17060.5 AAL63352.1 - 1.1 8.4 17.1 1.7 7.8 1.0 2.9 1 1 2 3 3 3 0 Monopolar spindle protein 2 DUF641 PF04859.12 AAL63352.1 - 1.1 9.6 21.4 1 9.7 2.1 3.0 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) SYCE1 PF15233.6 AAL63352.1 - 1.2 9.2 23.1 5.2 7.1 13.7 2.8 1 1 1 2 2 2 0 Synaptonemal complex central element protein 1 HalX PF08663.10 AAL63352.1 - 1.2 9.5 35.8 0.87 10.0 1.8 5.7 1 1 4 5 5 5 0 HalX domain AIP3 PF03915.13 AAL63352.1 - 1.2 8.1 14.7 2.6 7.0 14.7 1.4 1 1 0 1 1 1 0 Actin interacting protein 3 USP8_interact PF08941.10 AAL63352.1 - 1.3 8.9 20.4 0.4 10.5 2.0 3.5 2 1 2 4 4 3 0 USP8 interacting PI_PP_I PF18363.1 AAL63352.1 - 1.3 9.3 3.7 26 5.1 0.3 2.7 1 1 1 2 2 2 0 Phosphoinositide phosphatase insertion domain DUF5098 PF17023.5 AAL63352.1 - 1.3 7.9 10.2 3.1 6.7 10.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5098) MctB PF11382.8 AAL63352.1 - 1.6 8.4 25.4 1.3 8.7 12.6 3.1 1 1 2 3 3 3 0 Copper transport outer membrane protein, MctB DUF745 PF05335.13 AAL63352.1 - 1.6 8.4 32.1 1 9.1 13.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF745) YkyA PF10368.9 AAL63352.1 - 1.6 8.3 29.1 14 5.3 27.5 2.1 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein DUF773 PF05600.12 AAL63352.1 - 1.6 7.3 21.2 2.3 6.9 12.8 2.2 1 1 1 2 2 2 0 CDK5 regulatory subunit-associated protein 3 POTRA_2 PF08479.11 AAL63352.1 - 1.7 8.5 5.0 2.5 8.0 0.2 3.1 1 1 2 3 3 2 0 POTRA domain, ShlB-type Sigma70_ner PF04546.13 AAL63352.1 - 1.8 8.4 17.0 2.2 8.1 5.3 2.5 1 1 1 2 2 2 0 Sigma-70, non-essential region FAD_binding_1 PF00667.20 AAL63352.1 - 1.9 8.0 7.7 5.6 6.5 7.8 1.7 1 1 0 1 1 1 0 FAD binding domain DUF2968 PF11180.8 AAL63352.1 - 2 8.0 39.8 3.4 7.3 5.6 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2968) LPP PF04728.13 AAL63352.1 - 2.2 8.7 25.5 6.9 7.1 0.1 4.5 2 1 1 3 3 2 0 Lipoprotein leucine-zipper ERM PF00769.19 AAL63352.1 - 2.5 7.9 34.6 15 5.3 32.3 2.0 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Rho_Binding PF08912.11 AAL63352.1 - 2.7 8.9 27.7 3.4 8.6 2.4 4.3 2 1 2 4 4 4 0 Rho Binding ApoO PF09769.9 AAL63352.1 - 3 7.8 10.7 21 5.1 0.2 3.4 1 1 1 2 2 2 0 Apolipoprotein O ACCA PF03255.14 AAL63352.1 - 3.5 7.5 15.2 9.6 6.1 0.8 3.1 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit V_ATPase_I PF01496.19 AAL63352.1 - 4 5.2 15.7 1.4e+02 0.1 15.8 2.1 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Csm1_N PF18504.1 AAL63352.1 - 4.1 7.8 26.6 1.8 9.0 3.7 4.4 1 1 2 3 3 3 0 Csm1 N-terminal domain Cep57_CLD PF14073.6 AAL63352.1 - 4.2 7.4 28.1 6.2 6.8 25.0 2.0 1 1 1 2 2 2 0 Centrosome localisation domain of Cep57 DASH_Dad3 PF08656.10 AAL63352.1 - 4.3 7.5 17.9 0.89 9.7 0.7 3.9 3 2 0 3 3 2 0 DASH complex subunit Dad3 LMBR1 PF04791.16 AAL63352.1 - 4.9 5.9 12.3 21 3.8 12.3 1.9 1 1 0 1 1 1 0 LMBR1-like membrane protein Fungal_TACC PF12709.7 AAL63352.1 - 5.3 7.6 17.6 0.49 10.9 1.5 3.9 1 1 1 3 3 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins HAUS6_N PF14661.6 AAL63352.1 - 5.7 6.4 24.2 0.64 9.5 7.8 2.8 1 1 1 2 2 1 0 HAUS augmin-like complex subunit 6 N-terminus Sas10_Utp3 PF04000.15 AAL63352.1 - 5.8 7.6 17.4 2.2 9.0 1.2 4.1 2 1 0 2 2 1 0 Sas10/Utp3/C1D family MutS_IV PF05190.18 AAL63352.1 - 6 7.3 16.8 8.4 6.8 0.2 4.6 1 1 3 4 4 4 0 MutS family domain IV DUF4527 PF15030.6 AAL63352.1 - 6.1 6.2 24.0 5 6.5 10.2 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF4527) CENP-K PF11802.8 AAL63352.1 - 6.1 6.3 17.9 19 4.7 17.9 1.8 1 1 0 1 1 1 0 Centromere-associated protein K CREPT PF16566.5 AAL63352.1 - 6.4 6.9 21.5 5.2 7.2 1.8 2.8 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Hrs_helical PF12210.8 AAL63352.1 - 7.2 7.2 20.2 2.8 8.5 9.3 3.1 1 1 2 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate UPF0270 PF06794.12 AAL63352.1 - 7.3 6.8 7.5 1.9 8.6 1.6 2.9 2 2 0 2 2 1 0 Uncharacterised protein family (UPF0270) DUF3322 PF11795.8 AAL63352.1 - 7.5 6.5 11.8 5.1 7.1 8.0 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) HALZ PF02183.18 AAL63352.1 - 7.9 6.8 32.2 2.7 8.3 1.2 5.8 2 1 4 6 6 6 0 Homeobox associated leucine zipper DUF3837 PF12939.7 AAL63352.1 - 8.8 6.8 7.1 9.4 6.7 0.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3837) Radical_SAM PF04055.21 AAL63353.1 - 2.5e-12 47.5 0.0 5.1e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 AAL63353.1 - 6.1e-05 23.3 0.0 0.00013 22.3 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AAL63353.1 - 0.0029 17.7 0.0 0.0053 16.9 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain YqjK PF13997.6 AAL63353.1 - 0.14 12.5 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 YqjK-like protein ATPase_2 PF01637.18 AAL63354.1 - 7.6e-08 32.6 0.0 1.1e-07 32.1 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 AAL63354.1 - 0.045 13.8 0.0 0.12 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain Nitrate_red_del PF02613.15 AAL63355.1 - 1.8e-05 24.7 0.1 2.6e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 Nitrate reductase delta subunit Fer4_11 PF13247.6 AAL63357.1 - 3.6e-29 100.8 8.9 3.6e-29 100.8 8.9 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AAL63357.1 - 1.3e-15 57.7 28.2 1.4e-08 35.2 9.0 3.2 2 2 1 3 3 3 3 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAL63357.1 - 6.3e-13 48.7 45.8 8e-06 25.9 7.9 3.0 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4 PF00037.27 AAL63357.1 - 9.1e-13 47.4 40.6 5.3e-09 35.5 2.9 5.8 5 1 0 5 5 5 3 4Fe-4S binding domain Fer4_10 PF13237.6 AAL63357.1 - 1.2e-12 47.7 27.9 1e-07 31.9 8.8 3.3 2 1 1 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.7 AAL63357.1 - 4.2e-11 42.4 35.1 4.2e-07 29.8 2.0 4.5 5 0 0 5 5 5 4 4Fe-4S binding domain Fer4_2 PF12797.7 AAL63357.1 - 3.7e-10 39.3 32.4 5.9e-06 26.1 1.4 4.4 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4_3 PF12798.7 AAL63357.1 - 1.2e-09 38.4 44.4 0.00034 21.4 6.0 4.3 4 0 0 4 4 4 4 4Fe-4S binding domain Fer4_16 PF13484.6 AAL63357.1 - 1.4e-06 29.1 21.6 0.052 14.5 3.8 4.3 4 0 0 4 4 4 3 4Fe-4S double cluster binding domain Fer4_17 PF13534.6 AAL63357.1 - 1.9e-05 25.1 19.2 0.72 10.5 7.2 4.3 3 1 0 3 3 3 3 4Fe-4S dicluster domain Fer4_21 PF14697.6 AAL63357.1 - 0.00047 20.2 28.6 0.032 14.3 8.4 3.5 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_4 PF12800.7 AAL63357.1 - 0.0024 18.2 2.6 0.0024 18.2 2.6 4.5 4 1 0 4 4 4 1 4Fe-4S binding domain Fer4_8 PF13183.6 AAL63357.1 - 0.003 18.0 30.0 0.89 10.0 11.5 4.1 2 2 0 2 2 2 1 4Fe-4S dicluster domain TAT_signal PF10518.9 AAL63357.1 - 0.003 17.3 0.1 0.0064 16.3 0.1 1.6 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence Fer4_15 PF13459.6 AAL63357.1 - 0.014 16.1 0.7 0.014 16.1 0.7 3.4 4 0 0 4 4 3 0 4Fe-4S single cluster domain Fer4_18 PF13746.6 AAL63357.1 - 3.2 8.0 20.2 0.37 11.0 8.1 3.3 2 1 1 3 3 3 0 4Fe-4S dicluster domain Molybdopterin PF00384.22 AAL63359.1 - 2.5e-17 63.0 0.0 8e-13 48.1 0.0 2.8 2 1 0 2 2 2 2 Molybdopterin oxidoreductase Molydop_binding PF01568.21 AAL63359.1 - 1.5e-15 57.2 0.0 3.4e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 AAL63359.1 - 0.00042 20.2 0.4 0.0023 17.9 0.4 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain CDC48_N PF02359.18 AAL63359.1 - 0.1 12.8 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain LysE PF01810.18 AAL63360.1 - 1.4e-12 47.5 15.0 1.9e-12 47.1 15.0 1.2 1 0 0 1 1 1 1 LysE type translocator AAA_14 PF13173.6 AAL63361.1 - 4.8e-31 107.5 0.0 8.8e-31 106.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 AAL63361.1 - 0.00017 22.0 0.0 0.00042 20.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF4143 PF13635.6 AAL63361.1 - 0.00048 20.3 0.0 0.0029 17.7 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4143) AAA_16 PF13191.6 AAL63361.1 - 0.0026 18.2 0.1 0.35 11.2 0.1 3.0 2 1 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 AAL63361.1 - 0.0069 16.3 0.2 5.6 6.8 0.0 3.9 3 1 1 4 4 4 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 AAL63361.1 - 0.011 15.4 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AAL63361.1 - 0.024 14.9 0.0 7.3 6.9 0.0 2.5 1 1 1 2 2 2 0 AAA domain AAA_25 PF13481.6 AAL63361.1 - 0.16 11.5 0.1 1 8.9 0.0 2.2 2 1 0 2 2 2 0 AAA domain Nre_N PF04894.12 AAL63362.1 - 2.6e-97 325.9 0.0 3.5e-97 325.5 0.0 1.2 1 0 0 1 1 1 1 Archaeal Nre, N-terminal Nre_C PF04895.12 AAL63362.1 - 2.9e-35 120.5 0.1 5.3e-35 119.7 0.1 1.5 1 0 0 1 1 1 1 Archaeal Nre, C-terminal DUF2452 PF10504.9 AAL63362.1 - 0.057 12.9 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) MS_channel PF00924.18 AAL63363.1 - 9.6e-20 71.0 0.3 9.6e-20 71.0 0.3 1.9 1 1 1 2 2 2 1 Mechanosensitive ion channel TAL_effector PF03377.13 AAL63363.1 - 0.023 15.0 0.0 1.6 9.1 0.0 3.2 3 0 0 3 3 3 0 TAL effector repeat GatD_N PF18195.1 AAL63363.1 - 0.065 12.6 0.0 0.33 10.3 0.0 2.1 2 0 0 2 2 2 0 GatD N-terminal domain Tim17 PF02466.19 AAL63363.1 - 0.17 12.3 1.4 0.29 11.5 1.4 1.4 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family ATPase_2 PF01637.18 AAL63364.1 - 7.4e-65 219.1 0.0 1.2e-64 218.5 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_33 PF13671.6 AAL63364.1 - 0.0012 19.1 0.0 0.002 18.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 AAL63364.1 - 0.0029 16.8 0.0 0.0051 16.0 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 AAL63364.1 - 0.0033 17.8 0.3 0.0063 16.9 0.3 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AAL63364.1 - 0.0041 17.4 0.0 0.0079 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain MgsA_C PF12002.8 AAL63364.1 - 0.011 15.7 0.3 0.021 14.8 0.3 1.4 1 0 0 1 1 1 0 MgsA AAA+ ATPase C terminal AAA PF00004.29 AAL63364.1 - 0.05 14.0 0.0 0.12 12.8 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 AAL63364.1 - 0.056 13.5 0.0 0.13 12.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 AAL63364.1 - 0.16 11.8 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Glyco_transf_20 PF00982.21 AAL63365.1 - 7.6e-146 486.5 0.0 9.9e-146 486.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 AAL63365.1 - 8.9e-52 175.5 0.0 1.7e-51 174.6 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 AAL63365.1 - 1.4e-05 24.9 0.0 0.013 15.3 0.0 2.6 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.13 AAL63365.1 - 2.7e-05 23.8 0.0 6.9e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase Glyco_transf_5 PF08323.11 AAL63365.1 - 0.015 15.0 0.0 0.035 13.8 0.0 1.6 1 0 0 1 1 1 0 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 AAL63365.1 - 0.06 12.9 0.1 3.5 7.1 0.0 2.6 2 0 0 2 2 2 0 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AAL63366.1 - 2.6e-14 53.1 0.0 3.9e-13 49.3 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAL63366.1 - 7.5e-09 36.1 0.0 8.9e-08 32.6 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAL63366.1 - 3.5e-05 23.9 0.1 0.00034 20.7 0.1 2.3 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 AAL63366.1 - 0.00013 22.3 0.0 0.00027 21.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 AAL63366.1 - 0.016 15.7 0.0 0.035 14.6 0.0 1.6 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain TM_helix PF05552.12 AAL63367.1 - 0.0046 16.9 1.9 0.0046 16.9 1.9 3.9 4 0 0 4 4 4 1 Conserved TM helix EI24 PF07264.11 AAL63367.1 - 7.3 6.8 16.7 14 5.9 16.7 1.5 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DUF373 PF04123.13 AAL63367.1 - 9.5 5.6 23.4 18 4.6 23.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF373) Glycos_transf_1 PF00534.20 AAL63369.1 - 4.1e-24 85.0 0.0 1.3e-23 83.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAL63369.1 - 8e-07 29.6 0.0 1.3e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AAL63369.1 - 1e-06 29.0 0.0 2.1e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Hydrolase_3 PF08282.12 AAL63370.1 - 1.3e-08 34.9 0.0 0.00012 21.9 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.16 AAL63370.1 - 3.1e-05 23.2 0.0 5.6e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase PF00702.26 AAL63370.1 - 0.00061 20.1 0.0 0.0078 16.5 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 AAL63370.1 - 0.001 18.6 0.0 0.0021 17.6 0.0 1.4 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase HAD PF12710.7 AAL63370.1 - 0.0049 17.3 0.1 0.41 11.0 0.0 2.4 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 AAL63370.1 - 0.0095 16.0 0.0 0.91 9.6 0.0 2.2 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase CCG PF02754.16 AAL63371.1 - 3.8e-07 30.2 0.0 0.00066 19.9 0.0 2.6 2 1 0 2 2 2 2 Cysteine-rich domain Antimicrobial20 PF08256.11 AAL63371.1 - 0.24 12.0 4.4 1.9 9.2 0.4 2.5 2 0 0 2 2 2 0 Aurein-like antibiotic peptide Fer4_8 PF13183.6 AAL63372.1 - 1.8e-14 53.9 3.3 2.2e-14 53.6 3.3 1.1 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAL63372.1 - 1.6e-09 38.1 4.4 2.2e-09 37.7 4.4 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AAL63372.1 - 2.6e-09 37.5 5.2 3.5e-09 37.1 5.2 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 AAL63372.1 - 1.2e-06 28.1 14.4 5.8e-05 22.7 2.7 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 AAL63372.1 - 2.6e-06 27.5 8.6 7.2e-05 22.8 9.8 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_20 PF14691.6 AAL63372.1 - 2.3e-05 24.1 3.4 0.044 13.6 0.1 2.1 2 0 0 2 2 2 2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_9 PF13187.6 AAL63372.1 - 2.9e-05 24.1 7.9 0.00023 21.3 8.4 1.9 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAL63372.1 - 4.6e-05 24.3 5.1 0.0001 23.2 5.1 1.6 1 1 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_2 PF12797.7 AAL63372.1 - 6.7e-05 22.7 11.3 0.0013 18.7 1.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.6 AAL63372.1 - 0.001 19.3 4.5 0.12 12.6 0.3 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 AAL63372.1 - 0.0046 17.0 1.9 0.0046 17.0 1.9 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_22 PF17179.4 AAL63372.1 - 0.0086 16.9 9.0 0.53 11.2 2.0 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 AAL63372.1 - 0.0092 16.1 9.3 0.29 11.3 9.3 2.1 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_4 PF12800.7 AAL63372.1 - 0.031 14.8 10.3 1.2 9.8 1.1 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_3 PF12798.7 AAL63372.1 - 1.5 9.9 15.9 3.8 8.7 4.8 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain CCG PF02754.16 AAL63373.1 - 2.1e-20 72.7 0.0 8.6e-10 38.7 0.0 2.5 2 0 0 2 2 2 2 Cysteine-rich domain Fer4_8 PF13183.6 AAL63373.1 - 1.2e-11 44.8 2.9 1.2e-11 44.8 2.9 1.8 2 0 0 2 2 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAL63373.1 - 6.9e-11 42.5 3.4 1.6e-10 41.4 3.4 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AAL63373.1 - 6.9e-10 39.4 4.1 1.6e-09 38.2 4.1 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 AAL63373.1 - 9.1e-07 28.4 11.0 0.00092 18.9 1.4 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 AAL63373.1 - 7.6e-06 26.0 5.9 9.4e-05 22.5 7.0 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAL63373.1 - 3.9e-05 23.5 10.7 0.019 15.0 2.3 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 AAL63373.1 - 0.00023 21.3 8.1 0.007 16.5 9.4 2.5 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.7 AAL63373.1 - 0.00047 20.1 11.8 0.064 13.4 1.8 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 AAL63373.1 - 0.0005 20.4 10.2 0.022 15.2 1.3 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.6 AAL63373.1 - 0.057 13.6 1.2 10 6.3 0.2 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAL63373.1 - 0.27 12.2 12.3 6.5 7.8 2.9 2.4 1 1 1 2 2 2 0 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 AAL63373.1 - 0.46 10.6 12.2 7.5 6.8 10.9 2.8 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 AAL63373.1 - 9 7.2 13.0 13 6.7 2.0 2.8 2 1 1 3 3 2 0 4Fe-4S dicluster domain FAD_binding_4 PF01565.23 AAL63374.1 - 2.9e-23 82.1 0.0 4.2e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 AAL63374.1 - 0.00012 21.8 0.1 0.00028 20.6 0.1 1.6 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD-oxidase_C PF02913.19 AAL63375.1 - 4.3e-67 226.4 1.2 6.7e-67 225.7 0.7 1.6 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 AAL63375.1 - 1.4e-35 122.1 1.1 1.1e-34 119.1 1.1 2.3 1 1 0 1 1 1 1 FAD binding domain AP_endonuc_2 PF01261.24 AAL63375.1 - 0.00038 20.0 0.0 0.66 9.4 0.0 2.6 2 1 0 2 2 2 2 Xylose isomerase-like TIM barrel FAD_binding_5 PF00941.21 AAL63375.1 - 0.025 14.3 0.1 0.043 13.6 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain in molybdopterin dehydrogenase Malate_synthase PF01274.22 AAL63376.1 - 3.7e-40 137.7 0.0 3e-35 121.5 0.0 2.2 2 0 0 2 2 2 2 Malate synthase HpcH_HpaI PF03328.14 AAL63376.1 - 0.037 13.2 0.0 0.068 12.3 0.0 1.3 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family CCG PF02754.16 AAL63377.1 - 2.6e-06 27.6 0.0 0.00014 22.0 0.0 2.5 3 0 0 3 3 3 2 Cysteine-rich domain LUD_dom PF02589.15 AAL63378.1 - 1.5e-45 155.2 0.8 2.2e-45 154.7 0.8 1.2 1 0 0 1 1 1 1 LUD domain Fer4_8 PF13183.6 AAL63378.1 - 4.7e-10 39.8 1.7 9e-10 38.9 1.7 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAL63378.1 - 1.7e-08 34.9 0.5 3.3e-08 33.9 0.5 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AAL63378.1 - 3.3e-07 30.8 3.6 6.2e-07 29.9 3.6 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAL63378.1 - 5.7e-06 26.4 6.5 0.00012 22.2 7.2 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAL63378.1 - 1.3e-05 25.2 1.7 4.6e-05 23.5 1.8 1.8 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_20 PF14691.6 AAL63378.1 - 1.9e-05 24.4 2.4 0.0015 18.3 0.1 2.8 3 0 0 3 3 3 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4 PF00037.27 AAL63378.1 - 5.6e-05 22.8 6.3 0.0023 17.7 0.9 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 AAL63378.1 - 7.9e-05 22.6 6.3 0.0048 16.9 0.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 AAL63378.1 - 0.0001 22.5 6.0 0.036 14.6 0.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 AAL63378.1 - 0.00041 20.4 2.3 0.11 12.6 0.2 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAL63378.1 - 0.0015 18.5 7.8 0.14 12.4 1.6 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.6 AAL63378.1 - 0.0027 17.9 1.6 0.096 12.9 0.2 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_22 PF17179.4 AAL63378.1 - 0.017 16.0 3.5 0.72 10.7 0.2 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAL63378.1 - 0.027 15.4 6.3 0.15 13.0 6.3 2.2 1 1 0 1 1 1 0 4Fe-4S double cluster binding domain Aminotran_1_2 PF00155.21 AAL63378.1 - 0.11 11.7 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Fer4_13 PF13370.6 AAL63378.1 - 2.4 8.8 4.1 18 6.0 0.2 2.6 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Na_Ca_ex PF01699.24 AAL63379.1 - 0.00011 22.2 13.6 0.00011 22.2 13.6 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF5326 PF17260.2 AAL63380.1 - 0.078 13.1 2.6 0.076 13.2 2.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5326) DDDD PF10161.9 AAL63380.1 - 0.48 10.2 2.1 0.59 9.9 2.1 1.1 1 0 0 1 1 1 0 Putative mitochondrial precursor protein Flavin_Reduct PF01613.18 AAL63382.1 - 2.5e-22 79.6 0.0 4.7e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 Flavin reductase like domain HNH_repeat PF18780.1 AAL63382.1 - 0.0041 16.9 1.1 0.0077 16.0 1.1 1.4 1 0 0 1 1 1 1 Homing endonuclease repeat ABC_tran PF00005.27 AAL63383.1 - 5.6e-33 114.4 0.0 7.3e-33 114.0 0.0 1.1 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 AAL63383.1 - 8.4e-18 64.7 0.2 1.4e-17 63.9 0.2 1.4 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 AAL63383.1 - 2.1e-08 34.3 4.2 1.8e-06 28.0 0.5 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 AAL63383.1 - 0.00015 22.0 0.2 0.0011 19.2 0.2 2.0 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 AAL63383.1 - 0.002 17.6 0.1 0.031 13.7 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain TniB PF05621.11 AAL63383.1 - 0.0088 15.5 0.4 0.076 12.4 0.1 2.1 2 0 0 2 2 2 1 Bacterial TniB protein DUF87 PF01935.17 AAL63383.1 - 0.012 15.7 0.2 0.023 14.8 0.2 1.5 1 1 0 1 1 1 0 Helicase HerA, central domain AAA PF00004.29 AAL63383.1 - 0.012 16.0 0.0 0.067 13.6 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AAL63383.1 - 0.016 15.6 0.3 0.039 14.3 0.2 1.8 2 1 0 2 2 2 0 AAA ATPase domain DEAD PF00270.29 AAL63383.1 - 0.022 14.5 1.1 0.8 9.5 1.1 2.2 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_25 PF13481.6 AAL63383.1 - 0.022 14.3 0.2 0.42 10.1 0.2 2.4 2 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 AAL63383.1 - 0.046 12.8 0.0 0.07 12.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.14 AAL63383.1 - 0.083 12.9 0.5 0.37 10.8 0.3 2.1 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 AAL63383.1 - 0.13 12.1 0.1 0.22 11.3 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 AAL63383.1 - 0.21 11.3 0.1 4.1 7.1 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain NB-ARC PF00931.22 AAL63383.1 - 0.23 10.6 0.1 0.36 10.0 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 AAL63384.1 - 8.2e-26 91.2 0.0 1.1e-25 90.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 AAL63384.1 - 8.3e-18 64.7 0.2 1.5e-17 63.9 0.2 1.4 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 AAL63384.1 - 3.1e-08 33.8 0.1 7.8e-05 22.6 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAL63384.1 - 0.00067 19.2 0.0 0.43 10.0 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AAL63384.1 - 0.00094 19.5 0.5 0.01 16.1 0.5 2.1 1 1 0 1 1 1 1 AAA domain DUF87 PF01935.17 AAL63384.1 - 0.0033 17.5 0.0 0.0058 16.7 0.0 1.4 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_29 PF13555.6 AAL63384.1 - 0.0047 16.6 0.0 0.0082 15.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain TniB PF05621.11 AAL63384.1 - 0.0099 15.3 0.3 0.37 10.2 0.1 2.6 2 1 1 3 3 3 1 Bacterial TniB protein AAA_16 PF13191.6 AAL63384.1 - 0.018 15.5 0.1 0.034 14.5 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 AAL63384.1 - 0.096 13.2 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 AAL63384.1 - 0.098 11.4 0.6 0.48 9.2 0.1 2.3 2 1 0 2 2 2 0 Predicted ATPase of the ABC class adh_short_C2 PF13561.6 AAL63384.1 - 0.11 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase IstB_IS21 PF01695.17 AAL63384.1 - 0.14 11.9 0.0 5 6.8 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein BPD_transp_1 PF00528.22 AAL63385.1 - 1.9e-30 106.0 14.1 1.9e-30 106.0 14.1 2.2 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 AAL63385.1 - 0.00085 19.2 0.0 0.00085 19.2 0.0 3.1 3 1 0 3 3 3 1 N-terminal TM domain of oligopeptide transport permease C Sulf_transp PF04143.14 AAL63385.1 - 0.3 10.6 9.1 0.056 13.0 3.1 2.1 1 1 0 2 2 2 0 Sulphur transport BPD_transp_1 PF00528.22 AAL63386.1 - 1e-37 129.7 16.2 1e-37 129.7 16.2 1.9 3 0 0 3 3 3 1 Binding-protein-dependent transport system inner membrane component SBP_bac_5 PF00496.22 AAL63387.1 - 2.4e-59 201.2 12.5 9.2e-43 146.6 2.1 2.3 2 0 0 2 2 2 2 Bacterial extracellular solute-binding proteins, family 5 Middle DUF3530 PF12048.8 AAL63387.1 - 5.2 6.4 6.3 2 7.7 1.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3530) Tricorn_C1 PF14684.6 AAL63388.1 - 1.1e-30 105.5 0.5 2.1e-30 104.6 0.5 1.5 1 0 0 1 1 1 1 Tricorn protease C1 domain Tricorn_PDZ PF14685.6 AAL63388.1 - 3.6e-25 87.7 0.0 7.8e-25 86.7 0.0 1.5 1 0 0 1 1 1 1 Tricorn protease PDZ domain Peptidase_S41 PF03572.18 AAL63388.1 - 3.1e-23 82.2 0.0 6.5e-23 81.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase family S41 PD40 PF07676.12 AAL63388.1 - 2.1e-16 59.4 6.8 0.00053 19.8 0.1 7.2 7 0 0 7 7 7 3 WD40-like Beta Propeller Repeat ANAPC4_WD40 PF12894.7 AAL63388.1 - 2.3e-09 37.4 0.0 0.0012 19.1 0.0 4.2 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DPPIV_N PF00930.21 AAL63388.1 - 2.2e-05 23.4 0.0 0.76 8.5 0.0 5.0 4 2 1 5 5 5 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region WD40 PF00400.32 AAL63388.1 - 0.029 15.2 0.1 63 4.7 0.0 4.5 4 1 1 5 5 5 0 WD domain, G-beta repeat PQQ_2 PF13360.6 AAL63388.1 - 0.066 12.8 0.0 0.71 9.4 0.0 2.7 2 1 0 2 2 2 0 PQQ-like domain PQQ_3 PF13570.6 AAL63388.1 - 0.24 11.9 0.0 0.24 11.9 0.0 4.4 5 0 0 5 5 5 0 PQQ-like domain BNR PF02012.20 AAL63388.1 - 9.1 6.8 5.6 2.2 8.6 0.1 3.2 3 0 0 3 3 3 0 BNR/Asp-box repeat VKOR PF07884.14 AAL63389.1 - 1.1e-15 57.9 10.9 1.6e-15 57.4 10.9 1.3 1 1 0 1 1 1 1 Vitamin K epoxide reductase family PSII PF00421.19 AAL63389.1 - 0.08 11.6 0.7 0.091 11.4 0.7 1.1 1 0 0 1 1 1 0 Photosystem II protein G0-G1_switch_2 PF15103.6 AAL63389.1 - 9.3 6.7 6.0 3.9 7.9 1.2 2.2 2 0 0 2 2 2 0 G0/G1 switch protein 2 COXG PF06240.13 AAL63390.1 - 4.8e-41 139.8 0.1 5.4e-41 139.6 0.1 1.0 1 0 0 1 1 1 1 Carbon monoxide dehydrogenase subunit G (CoxG) Polyketide_cyc2 PF10604.9 AAL63390.1 - 3.6e-14 53.2 0.4 4.4e-14 53.0 0.4 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AAA_14 PF13173.6 AAL63391.1 - 0.0003 20.8 0.0 0.0006 19.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 AAL63391.1 - 0.0039 17.1 0.0 0.034 14.1 0.0 2.2 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea Fe_dep_repress PF01325.19 AAL63391.1 - 0.009 16.2 0.0 0.023 14.9 0.0 1.7 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain AAA_22 PF13401.6 AAL63391.1 - 0.02 15.1 0.0 4.6 7.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 AAL63391.1 - 0.21 11.3 0.0 0.36 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF4147 PF13660.6 AAL63393.1 - 1.7e-70 237.1 0.3 2.3e-70 236.7 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4147) MOFRL PF05161.13 AAL63393.1 - 5.7e-37 126.2 1.4 1.3e-36 125.1 1.4 1.7 1 0 0 1 1 1 1 MOFRL family HEPN PF05168.14 AAL63394.1 - 1.6e-33 115.3 2.2 1.8e-33 115.2 2.2 1.0 1 0 0 1 1 1 1 HEPN domain HEPN_AbiV PF18728.1 AAL63394.1 - 0.053 13.7 1.0 0.067 13.3 1.0 1.3 1 1 0 1 1 1 0 AbiV NTP_transf_2 PF01909.23 AAL63395.1 - 5.6e-09 36.2 0.0 6.7e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 AAL63395.1 - 8.4e-07 29.0 0.0 9.5e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase DUF294 PF03445.13 AAL63395.1 - 0.0079 16.0 0.0 0.0084 15.9 0.0 1.1 1 0 0 1 1 1 1 Putative nucleotidyltransferase DUF294 CBS PF00571.28 AAL63397.1 - 8.5e-25 87.0 2.9 1.7e-12 47.6 0.2 2.2 2 0 0 2 2 2 2 CBS domain DUF131 PF01998.17 AAL63398.1 - 1.9e-21 75.4 2.2 1.9e-21 75.4 2.2 2.0 1 1 1 2 2 2 1 Protein of unknown function DUF131 DUF2298 PF10060.9 AAL63398.1 - 0.21 10.2 2.9 0.25 10.0 2.9 1.0 1 0 0 1 1 1 0 Uncharacterized membrane protein (DUF2298) DUF3671 PF12420.8 AAL63398.1 - 0.37 10.9 3.4 1.3 9.1 3.4 1.9 1 1 0 1 1 1 0 Protein of unknown function DUF2207 PF09972.9 AAL63398.1 - 0.5 9.1 3.3 0.56 8.9 3.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF5383 PF17355.2 AAL63398.1 - 8.6 6.7 10.0 2.1 8.7 1.9 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5383) DUF131 PF01998.17 AAL63399.1 - 0.34 10.6 10.8 0.25 11.0 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF131 DUF2207 PF09972.9 AAL63399.1 - 4.2 6.0 8.4 6.2 5.5 8.4 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF202 PF02656.15 AAL63399.1 - 4.7 7.7 12.3 33 5.0 12.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF202) UPF0542 PF15086.6 AAL63399.1 - 9.9 6.2 7.4 14 5.7 0.4 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 HEPN PF05168.14 AAL63400.1 - 2.9e-10 40.3 0.3 3.5e-10 40.0 0.3 1.1 1 0 0 1 1 1 1 HEPN domain NTP_transf_2 PF01909.23 AAL63401.1 - 5.7e-15 55.4 0.0 8.7e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 AAL63401.1 - 3.6e-09 36.6 0.0 5.2e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase DNA_pol_B_palm PF14792.6 AAL63401.1 - 0.00026 21.2 0.0 0.0003 20.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase beta palm ABC_tran PF00005.27 AAL63402.1 - 1.2e-37 129.4 0.0 1.8e-37 128.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter OB_MalK PF17912.1 AAL63402.1 - 1.2e-05 26.0 0.1 4.6e-05 24.2 0.1 2.1 1 0 0 1 1 1 1 MalK OB fold domain AAA_21 PF13304.6 AAL63402.1 - 0.00013 21.9 0.1 0.25 11.1 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 AAL63402.1 - 0.00019 21.8 0.0 0.00046 20.6 0.0 1.7 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) TOBE_2 PF08402.10 AAL63402.1 - 0.00024 21.2 0.0 0.00057 20.0 0.0 1.7 1 0 0 1 1 1 1 TOBE domain AAA_16 PF13191.6 AAL63402.1 - 0.00067 20.1 0.1 0.0012 19.3 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 AAL63402.1 - 0.0018 17.8 0.0 0.076 12.4 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain TOBE PF03459.17 AAL63402.1 - 0.0019 18.5 0.0 0.006 16.8 0.0 1.9 1 0 0 1 1 1 1 TOBE domain Rad17 PF03215.15 AAL63402.1 - 0.002 18.1 0.0 0.003 17.5 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 AAL63402.1 - 0.0071 16.6 0.5 0.021 15.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 AAL63402.1 - 0.013 15.7 0.0 0.028 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 AAL63402.1 - 0.028 14.4 0.0 0.07 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AAL63402.1 - 0.04 13.5 0.1 0.27 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 AAL63402.1 - 0.04 13.8 0.3 0.13 12.2 0.0 1.9 2 1 0 2 2 2 0 RsgA GTPase RNA_helicase PF00910.22 AAL63402.1 - 0.041 14.3 0.0 0.079 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase sCache_3_2 PF17203.4 AAL63402.1 - 0.056 13.6 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Single cache domain 3 ATPase_2 PF01637.18 AAL63402.1 - 0.06 13.2 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea G-alpha PF00503.20 AAL63402.1 - 0.067 12.3 0.0 0.1 11.7 0.0 1.3 1 1 0 1 1 1 0 G-protein alpha subunit AAA_30 PF13604.6 AAL63402.1 - 0.087 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain HSM3_N PF18795.1 AAL63402.1 - 0.088 12.2 0.1 0.28 10.6 0.0 1.7 2 0 0 2 2 2 0 DNA mismatch repair protein HSM3, N terminal domain AAA_29 PF13555.6 AAL63402.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PduV-EutP PF10662.9 AAL63402.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 AAL63402.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 AAL63402.1 - 0.17 12.3 0.1 0.37 11.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AAL63402.1 - 0.17 12.4 0.2 0.35 11.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain BPD_transp_1 PF00528.22 AAL63403.1 - 2.3e-17 63.4 19.6 2.3e-17 63.4 19.6 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 AAL63404.1 - 3.3e-17 62.8 23.0 3.3e-17 62.8 23.0 1.9 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component SBP_bac_1 PF01547.25 AAL63405.1 - 1e-35 124.2 5.6 1e-35 124.2 5.6 1.7 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 AAL63405.1 - 5.6e-26 92.0 0.3 9.1e-26 91.3 0.3 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein FF PF01846.19 AAL63405.1 - 0.11 12.6 0.4 5.5 7.2 0.0 2.8 3 0 0 3 3 3 0 FF domain DEC-1_N PF04625.13 AAL63405.1 - 0.2 10.7 4.6 0.28 10.2 4.6 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region TALPID3 PF15324.6 AAL63405.1 - 2 6.0 9.1 2.9 5.5 9.1 1.1 1 0 0 1 1 1 0 Hedgehog signalling target Trypan_PARP PF05887.11 AAL63405.1 - 7.2 6.6 11.2 13 5.8 11.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) NusB PF01029.18 AAL63406.1 - 0.026 14.8 0.0 0.026 14.8 0.0 1.0 1 0 0 1 1 1 0 NusB family UDG PF03167.19 AAL63408.1 - 5.8e-40 136.8 0.0 7.2e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily EamA PF00892.20 AAL63409.1 - 1.5e-36 125.6 37.5 8e-21 74.7 16.4 2.0 2 0 0 2 2 2 2 EamA-like transporter family 4HBT PF03061.22 AAL63410.1 - 4.4e-17 62.2 0.1 5.9e-17 61.8 0.1 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 AAL63410.1 - 0.0024 18.2 0.0 0.0033 17.7 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4442 PF14539.6 AAL63410.1 - 0.079 13.1 0.0 0.24 11.5 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4442) HMGL-like PF00682.19 AAL63411.1 - 1.8e-53 181.8 0.0 4.1e-53 180.6 0.0 1.6 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 AAL63411.1 - 8e-25 87.3 0.0 1.4e-24 86.5 0.0 1.4 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Radical_SAM PF04055.21 AAL63411.1 - 0.069 13.5 0.0 3.5 8.0 0.0 2.9 1 1 1 2 2 2 0 Radical SAM superfamily Fer4_8 PF13183.6 AAL63412.1 - 4.8e-13 49.3 2.5 4.8e-13 49.3 2.5 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAL63412.1 - 7.8e-10 39.2 2.8 7.8e-10 39.2 2.8 2.2 2 1 0 2 2 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AAL63412.1 - 8.6e-10 39.1 4.8 4e-09 36.9 5.0 2.1 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAL63412.1 - 1.5e-08 35.4 2.3 1.5e-08 35.4 2.3 2.1 2 0 0 2 2 1 1 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 AAL63412.1 - 3.2e-08 33.6 6.6 3.2e-08 33.6 6.6 2.2 2 1 0 2 2 1 1 4Fe-4S dicluster domain CCG PF02754.16 AAL63412.1 - 9e-08 32.2 3.0 3.6e-07 30.3 0.6 2.9 3 0 0 3 3 3 1 Cysteine-rich domain Fer4_9 PF13187.6 AAL63412.1 - 3.9e-07 30.1 7.1 2.4e-05 24.4 8.6 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 AAL63412.1 - 2.9e-05 24.2 11.6 0.00045 20.5 2.2 2.8 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4 PF00037.27 AAL63412.1 - 3.7e-05 23.3 15.3 0.00012 21.7 4.3 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.6 AAL63412.1 - 0.00017 21.8 5.8 0.094 12.9 0.1 2.8 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 AAL63412.1 - 0.00018 21.6 5.4 0.047 13.8 1.3 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAL63412.1 - 0.00028 20.8 3.8 0.00028 20.8 3.8 2.9 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 AAL63412.1 - 0.0003 20.7 12.9 0.00056 19.9 3.0 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_22 PF17179.4 AAL63412.1 - 0.0041 17.9 4.7 0.45 11.4 0.2 2.8 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.6 AAL63412.1 - 0.024 15.4 2.6 0.33 11.7 0.3 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_3 PF12798.7 AAL63412.1 - 0.043 14.7 5.0 0.043 14.7 5.0 3.1 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_13 PF13370.6 AAL63412.1 - 0.07 13.7 8.1 0.29 11.7 1.8 2.6 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I ETF_QO PF05187.13 AAL63412.1 - 1.5 9.0 4.2 0.28 11.3 0.2 1.8 2 0 0 2 2 1 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S PCuAC PF04314.13 AAL63413.1 - 3.1e-11 43.0 0.0 4.1e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Copper chaperone PCu(A)C UbiA PF01040.18 AAL63414.1 - 6.8e-46 156.6 28.6 8.7e-46 156.3 28.6 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF996 PF06195.13 AAL63415.1 - 0.0023 18.2 12.1 0.024 14.9 12.1 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF996) RseC_MucC PF04246.12 AAL63416.1 - 0.051 13.5 0.7 0.054 13.5 0.7 1.0 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC DUF2207 PF09972.9 AAL63416.1 - 0.18 10.5 0.9 0.18 10.5 0.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) COX1 PF00115.20 AAL63417.1 - 2e-120 402.6 56.6 2e-120 402.6 56.6 3.0 2 1 1 3 3 3 1 Cytochrome C and Quinol oxidase polypeptide I COX3 PF00510.18 AAL63417.1 - 7.1e-15 55.5 14.9 7.1e-15 55.5 14.9 2.8 3 0 0 3 3 3 1 Cytochrome c oxidase subunit III COX2 PF00116.20 AAL63418.1 - 1.6e-13 50.6 0.1 7.6e-13 48.4 0.0 1.9 1 1 1 2 2 2 1 Cytochrome C oxidase subunit II, periplasmic domain Cupredoxin_1 PF13473.6 AAL63418.1 - 2.5e-05 24.3 0.0 3.8e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 Cupredoxin-like domain MFS_Mycoplasma PF07672.13 AAL63419.1 - 0.0067 15.8 1.2 0.0079 15.5 1.2 1.0 1 0 0 1 1 1 1 Mycoplasma MFS transporter NCU-G1 PF15065.6 AAL63419.1 - 0.047 12.7 0.7 0.055 12.4 0.7 1.1 1 0 0 1 1 1 0 Lysosomal transcription factor, NCU-G1 DUF4190 PF13828.6 AAL63419.1 - 0.12 12.1 1.1 0.12 12.1 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) DUF2070 PF09843.9 AAL63420.1 - 8.3 4.6 21.2 22 3.1 21.2 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) TMEM89 PF15098.6 AAL63421.1 - 0.097 12.9 0.1 0.24 11.6 0.1 1.6 1 0 0 1 1 1 0 TMEM89 protein family Cytochrom_C PF00034.21 AAL63422.1 - 0.00035 21.7 0.1 0.00076 20.6 0.1 1.7 1 1 0 1 1 1 1 Cytochrome c Cytochrom_C1 PF02167.15 AAL63422.1 - 0.0025 17.6 0.0 0.0066 16.2 0.0 1.7 1 1 1 2 2 2 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 AAL63422.1 - 0.053 13.9 0.1 0.3 11.4 0.0 2.1 1 1 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III FAP PF07174.11 AAL63422.1 - 0.24 10.8 12.6 0.4 10.1 12.6 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DUF4006 PF13179.6 AAL63422.1 - 1.6 8.7 4.0 3.8 7.5 4.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF4006) DEC-1_N PF04625.13 AAL63422.1 - 8.6 5.3 10.7 5.1 6.0 8.4 1.6 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region Rieske PF00355.26 AAL63423.1 - 1e-07 31.8 0.1 1.7e-07 31.1 0.1 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_Fe-S_N PF10399.9 AAL63423.1 - 0.0022 17.3 0.5 0.0042 16.4 0.1 1.6 2 0 0 2 2 2 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal TAT_signal PF10518.9 AAL63423.1 - 0.12 12.3 1.1 0.23 11.4 1.1 1.5 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Cytochrom_B_N_2 PF13631.6 AAL63424.1 - 2.2e-22 79.8 9.6 2.2e-22 79.8 9.6 2.0 3 0 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Cytochrome_B PF00033.19 AAL63424.1 - 3.9e-17 62.7 23.2 6.9e-15 55.4 13.4 2.9 3 0 0 3 3 3 2 Cytochrome b/b6/petB DUF4395 PF14340.6 AAL63424.1 - 0.01 16.2 0.4 0.01 16.2 0.4 3.7 3 1 0 3 3 3 1 Domain of unknown function (DUF4395) DUF4405 PF14358.6 AAL63424.1 - 0.017 15.7 12.1 0.027 15.0 0.8 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) Ferric_reduct PF01794.19 AAL63424.1 - 9.1 6.4 18.6 2.8 8.1 8.6 3.5 3 1 0 3 3 3 0 Ferric reductase like transmembrane component Wzy_C PF04932.15 AAL63425.1 - 0.88 9.2 8.6 0.83 9.3 7.8 1.5 1 1 0 1 1 1 0 O-Antigen ligase TMEMspv1-c74-12 PF11044.8 AAL63425.1 - 1.8 8.6 5.9 15 5.7 0.2 2.3 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein DUF4233 PF14017.6 AAL63425.1 - 3.5 8.0 12.3 0.89 9.9 8.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4233) Gram_pos_anchor PF00746.21 AAL63426.1 - 0.0015 18.4 2.5 1.3 9.0 0.0 2.2 2 0 0 2 2 2 2 LPXTG cell wall anchor motif COX2 PF00116.20 AAL63427.1 - 5.6e-07 29.5 0.4 8.2e-07 28.9 0.1 1.4 1 1 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain COX8 PF02285.15 AAL63427.1 - 5.4 7.0 6.2 3.7 7.5 4.1 1.8 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIII COX1 PF00115.20 AAL63428.1 - 4.8e-92 309.1 55.6 7.9e-92 308.3 55.6 1.4 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I SCO1-SenC PF02630.14 AAL63429.1 - 8.1e-22 77.6 0.0 1.3e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 AAL63429.1 - 9.5e-06 25.5 0.0 1.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AAL63429.1 - 0.018 14.7 0.0 0.06 13.1 0.0 1.8 1 1 0 1 1 1 0 Redoxin Sulfolobus_pRN PF05584.11 AAL63430.1 - 0.04 13.9 0.1 0.069 13.2 0.1 1.4 1 0 0 1 1 1 0 Sulfolobus plasmid regulatory protein MarR_2 PF12802.7 AAL63430.1 - 0.058 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 MarR family NosL PF05573.12 AAL63431.1 - 1e-09 38.8 0.1 3.8e-09 37.0 0.1 1.8 1 1 0 1 1 1 1 NosL NosL PF05573.12 AAL63432.1 - 0.00068 20.0 0.0 0.0011 19.3 0.0 1.2 1 0 0 1 1 1 1 NosL NosD PF05048.13 AAL63433.1 - 1.8e-20 73.2 0.5 1e-19 70.7 0.1 1.9 1 1 1 2 2 2 1 Periplasmic copper-binding protein (NosD) Beta_helix PF13229.6 AAL63433.1 - 3.7e-18 65.9 3.6 2e-10 40.8 0.1 2.4 1 1 1 2 2 2 2 Right handed beta helix region DUF3737 PF12541.8 AAL63433.1 - 0.092 11.9 0.1 2.6 7.2 0.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3737) Desulfoferrod_N PF06397.12 AAL63433.1 - 0.18 11.5 0.8 0.33 10.6 0.1 1.7 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain NHL PF01436.21 AAL63433.1 - 0.19 11.8 0.9 43 4.4 0.1 3.4 3 0 0 3 3 3 0 NHL repeat LpxD PF04613.14 AAL63433.1 - 0.2 11.5 0.4 1.6 8.6 0.0 2.2 2 0 0 2 2 2 0 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD ABC_tran PF00005.27 AAL63434.1 - 8.4e-14 52.3 0.0 2.1e-13 51.0 0.0 1.6 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAL63434.1 - 3.1e-11 43.7 0.0 0.00011 22.2 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AAL63434.1 - 0.0004 20.9 0.0 0.00054 20.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAL63434.1 - 0.0013 18.4 0.1 0.0021 17.8 0.1 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 AAL63434.1 - 0.016 14.9 0.0 0.022 14.5 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.19 AAL63434.1 - 0.04 13.3 0.1 0.059 12.8 0.1 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_27 PF13514.6 AAL63434.1 - 0.046 13.3 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain Pilin_N PF07790.11 AAL63436.1 - 0.064 14.2 0.1 0.15 13.0 0.0 1.6 2 0 0 2 2 2 0 Archaeal Type IV pilin, N-terminal PARM PF17061.5 AAL63436.1 - 0.3 11.2 0.5 0.37 10.9 0.5 1.2 1 0 0 1 1 1 0 PARM TrmB PF01978.19 AAL63437.1 - 2.8e-06 27.1 0.5 4.8e-06 26.4 0.5 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 AAL63437.1 - 4.1e-05 23.4 0.2 7.6e-05 22.5 0.2 1.5 1 0 0 1 1 1 1 MarR family TFIIE_alpha PF02002.17 AAL63437.1 - 0.00024 20.9 0.5 0.00082 19.2 0.5 1.8 1 1 0 1 1 1 1 TFIIE alpha subunit Dimerisation2 PF16864.5 AAL63437.1 - 0.00076 19.4 0.0 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain HTH_45 PF14947.6 AAL63437.1 - 0.00092 19.2 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix HTH_27 PF13463.6 AAL63437.1 - 0.0096 16.4 0.9 0.023 15.2 0.3 1.9 2 0 0 2 2 2 1 Winged helix DNA-binding domain Replic_Relax PF13814.6 AAL63437.1 - 0.01 15.9 0.3 0.014 15.4 0.3 1.1 1 0 0 1 1 1 0 Replication-relaxation DUF2250 PF10007.9 AAL63437.1 - 0.012 15.7 0.6 0.033 14.3 0.2 1.9 1 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) HTH_IclR PF09339.10 AAL63437.1 - 0.018 14.9 0.8 0.039 13.8 0.8 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain DUF4423 PF14394.6 AAL63437.1 - 0.02 14.6 0.1 0.03 14.0 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4423) DUF2802 PF10975.8 AAL63437.1 - 0.03 14.4 1.2 0.057 13.6 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) HTH_20 PF12840.7 AAL63437.1 - 0.048 13.7 1.1 0.1 12.7 1.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Phage_rep_org_N PF09681.10 AAL63437.1 - 0.062 13.2 0.0 0.084 12.8 0.0 1.2 1 0 0 1 1 1 0 N-terminal phage replisome organiser (Phage_rep_org_N) CtsR_C PF17727.1 AAL63437.1 - 0.073 13.2 0.1 0.13 12.4 0.1 1.5 1 1 0 1 1 1 0 CtsR C-terminal dimerization domain EamA PF00892.20 AAL63438.1 - 0.0012 19.1 20.7 0.068 13.3 12.5 2.8 2 1 0 2 2 2 2 EamA-like transporter family DUF3792 PF12670.7 AAL63438.1 - 0.12 12.5 13.1 0.65 10.2 4.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) DUF202 PF02656.15 AAL63438.1 - 1.9 9.0 14.0 1.2 9.6 8.3 3.0 2 2 0 2 2 2 0 Domain of unknown function (DUF202) EamA PF00892.20 AAL63439.1 - 1.7e-11 44.4 4.1 1.8e-11 44.3 4.1 1.0 1 0 0 1 1 1 1 EamA-like transporter family TMEM144 PF07857.12 AAL63439.1 - 0.029 13.4 0.1 0.029 13.4 0.1 1.1 1 0 0 1 1 1 0 Transmembrane family, TMEM144 of transporters VitK2_biosynth PF02621.14 AAL63440.1 - 8.9e-84 281.1 0.3 1e-83 281.0 0.3 1.0 1 0 0 1 1 1 1 Menaquinone biosynthesis Helicase_RecD PF05127.14 AAL63441.1 - 4e-53 179.9 0.0 7.3e-53 179.0 0.0 1.5 1 0 0 1 1 1 1 Helicase GNAT_acetyltr_2 PF13718.6 AAL63441.1 - 6.6e-43 146.7 0.0 4.2e-29 101.6 0.0 2.2 1 1 1 2 2 2 2 GNAT acetyltransferase 2 DUF1726 PF08351.11 AAL63441.1 - 4.3e-33 113.1 0.0 1.5e-32 111.3 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) Acetyltransf_1 PF00583.25 AAL63441.1 - 2e-05 24.8 0.0 4.6e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family tRNA_bind_2 PF13725.6 AAL63441.1 - 0.0028 17.4 0.0 0.0052 16.5 0.0 1.4 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_7 PF13508.7 AAL63441.1 - 0.013 15.9 0.1 0.056 13.9 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAL63441.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain EamA PF00892.20 AAL63442.1 - 6e-27 94.5 46.1 1.5e-13 51.1 18.9 2.1 2 0 0 2 2 2 2 EamA-like transporter family TMEM234 PF10639.9 AAL63442.1 - 0.0044 17.1 1.7 0.0044 17.1 1.7 2.5 2 1 0 2 2 2 2 Putative transmembrane family 234 eIF-5_eIF-2B PF01873.17 AAL63443.1 - 7.8e-29 99.9 0.0 9.1e-29 99.7 0.0 1.0 1 0 0 1 1 1 1 Domain found in IF2B/IF5 DUF35_N PF12172.8 AAL63443.1 - 0.011 15.6 0.1 0.011 15.6 0.1 2.1 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) A2L_zn_ribbon PF08792.10 AAL63443.1 - 0.099 12.4 0.6 5.3 6.9 0.0 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain Lar_restr_allev PF14354.6 AAL63443.1 - 0.11 12.8 0.4 0.21 12.0 0.4 1.4 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf-RRN7 PF11781.8 AAL63443.1 - 0.14 11.9 0.5 3.2 7.5 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 OB_aCoA_assoc PF01796.17 AAL63444.1 - 2e-14 53.3 0.0 3e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 DUF35 OB-fold domain, acyl-CoA-associated DUF35_N PF12172.8 AAL63444.1 - 1e-11 44.4 0.4 1.8e-11 43.7 0.4 1.3 1 0 0 1 1 1 1 Rubredoxin-like zinc ribbon domain (DUF35_N) TackOD1 PF18551.1 AAL63444.1 - 0.007 16.1 0.0 0.0091 15.7 0.0 1.2 1 0 0 1 1 1 1 Thaumarchaeal output domain 1 Ribosomal_L37e PF01907.19 AAL63444.1 - 0.013 15.7 0.2 0.021 15.0 0.2 1.3 1 0 0 1 1 1 0 Ribosomal protein L37e HypA PF01155.19 AAL63444.1 - 0.035 14.1 0.0 0.051 13.6 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TF_Zn_Ribbon PF08271.12 AAL63444.1 - 0.11 12.0 1.4 7 6.3 0.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding TFIIS_C PF01096.18 AAL63444.1 - 0.14 12.0 1.7 12 5.9 0.1 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-RING_5 PF14634.6 AAL63444.1 - 0.41 10.6 2.7 0.61 10.1 2.7 1.2 1 0 0 1 1 1 0 zinc-RING finger domain zinc_ribbon_4 PF13717.6 AAL63444.1 - 3.5 7.6 7.4 4.7 7.2 0.9 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Thiolase_N PF00108.23 AAL63445.1 - 2.5e-26 92.6 0.0 8.1e-26 90.9 0.0 1.8 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 AAL63445.1 - 9.1e-10 38.2 0.9 1.4e-08 34.4 0.0 2.9 2 1 1 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 AAL63445.1 - 8.1e-07 28.9 3.2 2.1e-05 24.3 0.7 2.8 3 0 0 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 AAL63445.1 - 5e-05 23.1 0.1 0.0029 17.4 0.1 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Acyl-CoA_dh_1 PF00441.24 AAL63446.1 - 1.2e-43 148.9 4.5 1.5e-43 148.5 3.7 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 AAL63446.1 - 1.8e-36 125.2 1.3 3.5e-36 124.3 0.1 2.1 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 AAL63446.1 - 5e-26 90.7 0.0 9.3e-26 89.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 AAL63446.1 - 3e-20 72.8 1.9 4.6e-20 72.2 1.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 AAL63446.1 - 0.15 12.6 0.0 0.38 11.3 0.0 1.7 2 0 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal AMP-binding PF00501.28 AAL63447.1 - 7.5e-110 367.4 0.0 8.9e-110 367.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAL63447.1 - 3.7e-21 75.9 1.5 1e-20 74.5 0.9 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Aldo_ket_red PF00248.21 AAL63448.1 - 3.2e-63 213.7 0.0 3.6e-63 213.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ECH_1 PF00378.20 AAL63449.1 - 5.1e-69 232.4 0.0 7e-69 231.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 3HCDH_N PF02737.18 AAL63449.1 - 4.3e-66 222.2 1.1 6.7e-66 221.6 1.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 AAL63449.1 - 3.4e-50 168.6 0.1 6.4e-24 84.4 0.0 2.9 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 AAL63449.1 - 2.4e-34 119.3 0.0 1.3e-33 116.9 0.0 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Pyr_redox_2 PF07992.14 AAL63449.1 - 0.0004 19.7 0.8 0.00097 18.4 0.4 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 AAL63449.1 - 0.001 19.6 0.7 0.0045 17.6 0.7 2.1 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 AAL63449.1 - 0.0011 19.1 0.0 0.0024 18.0 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox PF00070.27 AAL63449.1 - 0.021 15.4 0.4 0.1 13.1 0.2 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CbiA PF01656.23 AAL63449.1 - 0.022 14.8 0.0 0.084 12.9 0.0 1.9 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short_C2 PF13561.6 AAL63449.1 - 0.023 14.2 0.5 0.11 12.0 0.5 2.2 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase NAD_Gly3P_dh_N PF01210.23 AAL63449.1 - 0.034 14.1 1.1 0.1 12.6 0.6 2.1 1 1 1 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.14 AAL63449.1 - 0.064 12.8 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 AAL63449.1 - 0.085 13.1 0.2 0.31 11.3 0.1 2.1 2 0 0 2 2 2 0 TrkA-N domain MORN PF02493.20 AAL63449.1 - 2.1 8.4 3.5 40 4.4 0.2 3.0 3 0 0 3 3 3 0 MORN repeat Peptidase_M42 PF05343.14 AAL63450.1 - 3.1e-108 361.2 0.2 3.6e-108 361.0 0.2 1.0 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.28 AAL63450.1 - 1.4e-10 41.2 0.1 2.2e-10 40.6 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 AAL63450.1 - 1.5e-07 31.3 0.0 1.7e-05 24.6 0.0 2.5 2 1 0 2 2 2 2 Peptidase family M28 PhoU PF01895.19 AAL63451.1 - 4.5e-20 71.9 8.0 4.5e-12 46.3 0.9 2.4 2 1 0 2 2 2 2 PhoU domain DUF416 PF04222.12 AAL63451.1 - 0.011 15.2 0.7 0.38 10.2 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF416) DUF1699 PF08004.11 AAL63451.1 - 0.03 14.0 0.3 8.4 6.1 0.0 2.8 2 2 2 4 4 4 0 Protein of unknown function (DUF1699) ATP-cone PF03477.16 AAL63451.1 - 0.058 14.0 1.3 0.91 10.1 0.0 2.6 2 1 0 2 2 2 0 ATP cone domain DUF5330 PF17264.2 AAL63451.1 - 0.21 11.6 0.5 1.6 8.8 0.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5330) ARGLU PF15346.6 AAL63451.1 - 5.5 6.9 6.9 0.58 10.0 0.8 2.0 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 PaREP1 PF05942.11 AAL63452.1 - 2.4e-27 95.2 0.2 3e-27 94.8 0.2 1.1 1 0 0 1 1 1 1 Archaeal PaREP1/PaREP8 family HEPN PF05168.14 AAL63452.1 - 0.014 15.5 2.2 0.068 13.3 0.7 2.1 2 0 0 2 2 2 0 HEPN domain ABC_tran PF00005.27 AAL63453.1 - 1.5e-28 100.0 0.0 3e-28 99.0 0.0 1.5 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 AAL63453.1 - 1.7e-10 41.3 0.2 1.3e-06 28.5 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system BCA_ABC_TP_C PF12399.8 AAL63453.1 - 0.00061 19.6 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter SMC_N PF02463.19 AAL63453.1 - 0.0013 18.2 0.6 0.73 9.2 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_19 PF13245.6 AAL63453.1 - 0.0052 17.1 0.5 0.023 15.0 0.5 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AAL63453.1 - 0.0054 16.5 0.5 0.032 13.9 0.5 1.9 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 AAL63453.1 - 0.0058 16.8 0.1 0.061 13.6 0.1 2.2 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 AAL63453.1 - 0.0072 16.6 0.3 3.1 8.1 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 AAL63453.1 - 0.017 15.5 0.0 0.029 14.8 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 AAL63453.1 - 0.021 15.3 0.5 0.034 14.6 0.5 1.3 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 AAL63453.1 - 0.043 13.4 0.1 0.069 12.8 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA PF00004.29 AAL63453.1 - 0.065 13.7 0.7 0.68 10.4 0.7 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MukB PF04310.12 AAL63453.1 - 0.067 13.0 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 MukB N-terminal AAA_27 PF13514.6 AAL63453.1 - 0.068 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AAL63453.1 - 0.083 12.6 0.2 0.16 11.7 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain KdpD PF02702.17 AAL63453.1 - 0.1 12.1 0.0 4.4 6.7 0.0 2.3 1 1 1 2 2 2 0 Osmosensitive K+ channel His kinase sensor domain ABC_tran PF00005.27 AAL63454.1 - 4.6e-29 101.7 0.0 6.3e-29 101.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter BCA_ABC_TP_C PF12399.8 AAL63454.1 - 3.1e-08 33.3 0.3 7.4e-08 32.1 0.2 1.8 2 0 0 2 2 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_21 PF13304.6 AAL63454.1 - 2.3e-07 31.0 0.6 0.00022 21.1 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAL63454.1 - 3.9e-07 29.7 0.1 0.0069 15.9 0.1 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AAL63454.1 - 4.7e-05 24.0 0.1 9.4e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAL63454.1 - 0.00012 21.7 0.0 0.00028 20.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AAL63454.1 - 0.00029 21.1 0.4 0.0081 16.4 0.4 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AAL63454.1 - 0.00057 19.7 0.1 0.0057 16.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.9 AAL63454.1 - 0.0009 18.2 0.3 0.77 8.5 0.0 2.1 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 AAL63454.1 - 0.0024 18.3 0.1 0.0045 17.4 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.6 AAL63454.1 - 0.0036 17.1 0.0 0.005 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain SRP54 PF00448.22 AAL63454.1 - 0.0094 15.6 0.0 0.086 12.5 0.0 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain T2SSE PF00437.20 AAL63454.1 - 0.014 14.5 0.2 0.046 12.8 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein ATP-synt_ab PF00006.25 AAL63454.1 - 0.018 14.7 0.0 0.024 14.3 0.0 1.1 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.22 AAL63454.1 - 0.022 14.0 0.1 0.16 11.1 0.0 2.1 2 1 0 2 2 2 0 NB-ARC domain RsgA_GTPase PF03193.16 AAL63454.1 - 0.023 14.6 0.0 0.041 13.8 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase ATPase_2 PF01637.18 AAL63454.1 - 0.031 14.2 0.1 0.041 13.8 0.1 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 AAL63454.1 - 0.031 14.3 0.0 1.4 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 AAL63454.1 - 0.032 13.6 0.3 1.3 8.4 0.1 2.2 2 0 0 2 2 2 0 Bacterial TniB protein AAA PF00004.29 AAL63454.1 - 0.054 13.9 0.1 2.8 8.4 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 AAL63454.1 - 0.056 13.0 0.3 0.34 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 AAL63454.1 - 0.058 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_27 PF13514.6 AAL63454.1 - 0.069 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 AAL63454.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 AAL63454.1 - 0.17 12.1 0.1 0.8 9.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain DLIC PF05783.11 AAL63454.1 - 0.2 10.4 0.0 0.38 9.5 0.0 1.4 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) AAA_19 PF13245.6 AAL63454.1 - 0.23 11.8 0.3 0.46 10.8 0.1 1.8 1 1 1 2 2 2 0 AAA domain BPD_transp_2 PF02653.16 AAL63455.1 - 6.1e-30 104.3 47.8 8.9e-30 103.8 47.8 1.2 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component Pam17 PF08566.10 AAL63455.1 - 0.85 9.4 4.7 0.78 9.6 1.9 2.2 1 1 1 2 2 2 0 Mitochondrial import protein Pam17 BPD_transp_2 PF02653.16 AAL63456.1 - 1.1e-32 113.3 49.0 1.3e-32 113.1 49.0 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component Peripla_BP_6 PF13458.6 AAL63457.1 - 2.1e-53 182.2 2.2 2.1e-53 182.2 2.2 1.7 2 0 0 2 2 2 1 Periplasmic binding protein ANF_receptor PF01094.28 AAL63457.1 - 5.8e-14 51.9 0.0 8.1e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_5 PF13433.6 AAL63457.1 - 2.7e-11 43.1 0.3 1.7e-09 37.1 0.1 2.2 2 0 0 2 2 2 2 Periplasmic binding protein domain ABC_sub_bind PF04392.12 AAL63457.1 - 1.9e-05 24.1 0.2 3e-05 23.4 0.2 1.3 1 0 0 1 1 1 1 ABC transporter substrate binding protein Peripla_BP_4 PF13407.6 AAL63457.1 - 0.0015 18.2 1.6 0.026 14.1 1.0 2.9 2 2 0 2 2 2 1 Periplasmic binding protein domain Mucin PF01456.17 AAL63457.1 - 0.33 10.9 19.2 0.52 10.3 19.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF2613 PF11021.8 AAL63457.1 - 0.75 9.9 4.2 6.5 6.9 1.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) ABC_tran PF00005.27 AAL63458.1 - 1.1e-32 113.4 0.0 1.4e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAL63458.1 - 9e-11 42.1 0.0 6.8e-05 22.8 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAL63458.1 - 6.8e-07 28.9 0.0 9.2e-05 22.0 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AAL63458.1 - 3.8e-06 27.2 0.0 8.7e-06 26.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAL63458.1 - 1.7e-05 24.5 0.0 3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 AAL63458.1 - 0.00058 19.7 0.0 0.02 14.6 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 AAL63458.1 - 0.00073 19.5 0.0 0.0016 18.3 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 AAL63458.1 - 0.0011 19.4 0.2 0.0026 18.1 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 AAL63458.1 - 0.0029 18.1 1.6 0.0085 16.6 1.6 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AAL63458.1 - 0.01 15.6 0.0 0.026 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 AAL63458.1 - 0.011 15.7 0.0 0.033 14.1 0.0 1.8 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_PrkA PF08298.11 AAL63458.1 - 0.035 13.0 0.0 0.054 12.4 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain AAA_18 PF13238.6 AAL63458.1 - 0.038 14.5 0.0 0.1 13.2 0.0 1.8 2 1 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 AAL63458.1 - 0.047 13.9 0.1 1 9.7 0.1 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Adeno_IVa2 PF02456.15 AAL63458.1 - 0.098 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_25 PF13481.6 AAL63458.1 - 0.14 11.7 0.3 0.47 10.0 0.1 1.9 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 AAL63458.1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain BPD_transp_1 PF00528.22 AAL63459.1 - 2.8e-11 43.5 11.7 2.8e-11 43.5 11.7 2.4 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 AAL63460.1 - 1.3e-10 41.3 21.2 1.3e-10 41.3 21.2 3.1 1 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component MscL PF01741.18 AAL63460.1 - 6.8 7.0 16.5 0.068 13.5 1.3 3.4 3 1 0 3 3 3 0 Large-conductance mechanosensitive channel, MscL PBP_like_2 PF12849.7 AAL63461.1 - 4.8e-50 170.8 3.7 6e-50 170.5 3.7 1.0 1 0 0 1 1 1 1 PBP superfamily domain PBP_like PF12727.7 AAL63461.1 - 8e-07 28.4 0.0 3.3e-06 26.4 0.0 1.8 1 1 0 1 1 1 1 PBP superfamily domain FixQ PF05545.11 AAL63461.1 - 0.053 13.5 0.5 0.15 12.1 0.5 1.8 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ PhoU PF01895.19 AAL63462.1 - 0.0015 18.9 1.0 0.0034 17.8 0.1 2.0 2 1 0 2 2 2 1 PhoU domain SWIM PF04434.17 AAL63464.1 - 0.00024 20.7 0.1 0.00052 19.6 0.1 1.5 1 0 0 1 1 1 1 SWIM zinc finger Pertussis_S2S3 PF02918.15 AAL63465.1 - 0.02 14.8 0.5 0.56 10.1 0.1 2.2 1 1 1 2 2 2 0 Pertussis toxin, subunit 2 and 3, C-terminal domain EthD PF07110.11 AAL63465.1 - 0.13 13.4 0.0 0.2 12.8 0.0 1.3 1 0 0 1 1 1 0 EthD domain Bacteriocin_IIc PF10439.9 AAL63466.1 - 0.3 11.2 2.4 30 4.8 2.2 2.6 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide ABA_GPCR PF12430.8 AAL63468.1 - 0.065 13.0 0.4 0.19 11.5 0.4 1.9 1 1 0 1 1 1 0 Abscisic acid G-protein coupled receptor Baculo_PEP_C PF04513.12 AAL63471.1 - 1.5e-05 25.1 0.4 3.4e-05 23.9 0.4 1.6 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus KxDL PF10241.9 AAL63471.1 - 0.00015 22.0 4.1 0.11 12.8 0.9 2.2 1 1 1 2 2 2 2 Uncharacterized conserved protein CdvA PF18822.1 AAL63471.1 - 0.00016 21.5 10.7 0.0041 16.9 3.4 2.1 1 1 1 2 2 2 2 CdvA-like coiled-coil domain OmpH PF03938.14 AAL63471.1 - 0.00049 20.4 0.5 0.00069 20.0 0.5 1.2 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) Apolipoprotein PF01442.18 AAL63471.1 - 0.0008 19.3 4.2 0.00095 19.1 4.2 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Spc7 PF08317.11 AAL63471.1 - 0.00097 18.1 5.2 0.0013 17.7 5.2 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein CREPT PF16566.5 AAL63471.1 - 0.0011 19.2 4.4 0.0023 18.1 4.2 1.5 1 1 1 2 2 2 1 Cell-cycle alteration and expression-elevated protein in tumour DUF1664 PF07889.12 AAL63471.1 - 0.0011 19.0 2.9 0.0016 18.5 2.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Gp-FAR-1 PF05823.12 AAL63471.1 - 0.0015 18.9 1.2 0.002 18.5 1.2 1.2 1 0 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) FlxA PF14282.6 AAL63471.1 - 0.0017 18.3 0.4 0.0099 15.9 0.3 2.0 1 1 0 1 1 1 1 FlxA-like protein COG2 PF06148.11 AAL63471.1 - 0.0023 18.0 4.8 0.0035 17.4 4.5 1.5 1 1 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Prefoldin_2 PF01920.20 AAL63471.1 - 0.0029 17.5 4.7 0.0042 17.0 2.5 2.1 1 1 1 2 2 2 1 Prefoldin subunit Occludin_ELL PF07303.13 AAL63471.1 - 0.003 18.2 2.5 0.0042 17.8 2.5 1.3 1 0 0 1 1 1 1 Occludin homology domain DASH_Spc34 PF08657.10 AAL63471.1 - 0.0031 17.4 0.3 0.0034 17.2 0.3 1.2 1 0 0 1 1 1 1 DASH complex subunit Spc34 ApoLp-III PF07464.11 AAL63471.1 - 0.0032 17.6 0.1 0.0039 17.3 0.1 1.2 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) PTRF_SDPR PF15237.6 AAL63471.1 - 0.0032 17.1 3.5 0.005 16.5 3.5 1.3 1 1 0 1 1 1 1 PTRF/SDPR family FH2 PF02181.23 AAL63471.1 - 0.0033 16.6 1.1 0.0038 16.4 1.1 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain Lectin_N PF03954.14 AAL63471.1 - 0.0033 17.1 1.8 0.0055 16.4 0.6 1.8 1 1 1 2 2 2 1 Hepatic lectin, N-terminal domain Mod_r PF07200.13 AAL63471.1 - 0.0035 17.5 2.7 0.0044 17.1 2.7 1.2 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein GrpE PF01025.19 AAL63471.1 - 0.0036 17.0 2.1 0.0046 16.6 2.1 1.3 1 0 0 1 1 1 1 GrpE DASH_Dam1 PF08653.10 AAL63471.1 - 0.0042 16.8 4.3 0.49 10.2 0.8 3.0 1 1 2 3 3 3 1 DASH complex subunit Dam1 FlgN PF05130.12 AAL63471.1 - 0.0047 17.4 2.3 0.0058 17.1 2.3 1.1 1 0 0 1 1 1 1 FlgN protein DUF3584 PF12128.8 AAL63471.1 - 0.0054 14.3 1.8 0.006 14.2 1.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) PhaP_Bmeg PF09602.10 AAL63471.1 - 0.0056 16.6 1.0 0.0074 16.2 1.0 1.1 1 0 0 1 1 1 1 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF1640 PF07798.11 AAL63471.1 - 0.0056 16.7 6.5 0.0065 16.5 6.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) LPP PF04728.13 AAL63471.1 - 0.0061 16.9 1.2 0.3 11.5 0.0 3.1 1 1 1 2 2 2 1 Lipoprotein leucine-zipper Fzo_mitofusin PF04799.13 AAL63471.1 - 0.0068 16.0 3.9 0.13 11.8 1.1 2.0 1 1 1 2 2 2 2 fzo-like conserved region LOH1CR12 PF10158.9 AAL63471.1 - 0.0071 16.4 0.6 0.009 16.0 0.6 1.3 1 0 0 1 1 1 1 Tumour suppressor protein DLP_helical PF18709.1 AAL63471.1 - 0.0072 15.6 1.2 0.0085 15.3 1.2 1.2 1 0 0 1 1 1 1 Dynamin-like helical domain IFT57 PF10498.9 AAL63471.1 - 0.0075 15.3 1.3 0.0089 15.0 1.3 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 DUF4618 PF15397.6 AAL63471.1 - 0.0076 15.7 4.5 0.082 12.3 4.4 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4618) Ran-binding PF05508.11 AAL63471.1 - 0.0077 15.2 1.5 0.0091 15.0 1.5 1.1 1 0 0 1 1 1 1 RanGTP-binding protein Fmp27_WPPW PF10359.9 AAL63471.1 - 0.0083 15.0 2.2 0.0098 14.8 2.2 1.1 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain TMPIT PF07851.13 AAL63471.1 - 0.0083 15.4 1.0 0.0095 15.2 1.0 1.1 1 0 0 1 1 1 1 TMPIT-like protein AAA_32 PF13654.6 AAL63471.1 - 0.011 14.6 1.1 0.012 14.4 1.1 1.1 1 0 0 1 1 1 0 AAA domain Phage_GP20 PF06810.11 AAL63471.1 - 0.011 15.5 1.5 0.017 14.9 1.4 1.4 1 1 0 1 1 1 0 Phage minor structural protein GP20 DUF4446 PF14584.6 AAL63471.1 - 0.013 15.5 1.5 0.018 15.0 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) HAUS5 PF14817.6 AAL63471.1 - 0.013 14.3 3.1 0.014 14.2 3.1 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 FapA PF03961.13 AAL63471.1 - 0.014 14.1 3.0 0.015 13.9 3.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A NPV_P10 PF05531.12 AAL63471.1 - 0.014 15.9 0.5 0.19 12.2 0.5 2.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein T3SS_needle_F PF09392.10 AAL63471.1 - 0.015 15.5 0.2 0.75 10.0 0.1 2.3 1 1 1 2 2 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF AAA_13 PF13166.6 AAL63471.1 - 0.015 14.0 1.8 0.017 13.8 1.8 1.0 1 0 0 1 1 1 0 AAA domain DUF2452 PF10504.9 AAL63471.1 - 0.016 14.6 0.8 0.028 13.9 0.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2452) Atg14 PF10186.9 AAL63471.1 - 0.018 14.1 2.9 0.021 13.9 2.9 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 YlqD PF11068.8 AAL63471.1 - 0.02 15.2 0.6 0.028 14.8 0.6 1.2 1 0 0 1 1 1 0 YlqD protein Ax_dynein_light PF10211.9 AAL63471.1 - 0.021 14.8 2.8 0.025 14.5 2.8 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain Fez1 PF06818.15 AAL63471.1 - 0.021 15.3 2.2 0.023 15.1 2.2 1.2 1 0 0 1 1 1 0 Fez1 Spectrin PF00435.21 AAL63471.1 - 0.022 15.2 0.8 0.031 14.8 0.8 1.3 1 0 0 1 1 1 0 Spectrin repeat UPF0242 PF06785.11 AAL63471.1 - 0.022 14.9 5.2 0.025 14.7 5.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF489 PF04356.12 AAL63471.1 - 0.022 14.8 0.7 0.027 14.5 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF489) Syntaxin-6_N PF09177.11 AAL63471.1 - 0.023 15.2 2.6 0.28 11.7 0.2 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF948 PF06103.11 AAL63471.1 - 0.024 14.9 0.4 0.054 13.8 0.4 1.8 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) FAM76 PF16046.5 AAL63471.1 - 0.027 13.8 5.2 0.032 13.6 5.2 1.1 1 0 0 1 1 1 0 FAM76 protein CENP-F_leu_zip PF10473.9 AAL63471.1 - 0.027 14.5 7.6 0.046 13.7 7.4 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TFR_dimer PF04253.15 AAL63471.1 - 0.027 14.5 0.8 0.042 14.0 0.8 1.3 1 0 0 1 1 1 0 Transferrin receptor-like dimerisation domain Med4 PF10018.9 AAL63471.1 - 0.028 14.1 3.8 0.048 13.3 3.8 1.5 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Laminin_II PF06009.12 AAL63471.1 - 0.03 14.4 2.1 0.042 13.9 2.1 1.3 1 0 0 1 1 1 0 Laminin Domain II FliD_C PF07195.12 AAL63471.1 - 0.031 13.7 0.6 0.051 13.0 0.3 1.5 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DUF3375 PF11855.8 AAL63471.1 - 0.032 13.2 2.3 0.042 12.8 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) DASH_Hsk3 PF08227.11 AAL63471.1 - 0.033 14.5 0.3 1.5 9.2 0.1 2.5 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like APG6_N PF17675.1 AAL63471.1 - 0.034 14.7 4.4 0.045 14.3 4.4 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Mitofilin PF09731.9 AAL63471.1 - 0.037 12.9 4.2 0.043 12.7 4.2 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SPX PF03105.19 AAL63471.1 - 0.039 13.9 3.7 0.054 13.4 3.7 1.3 1 1 0 1 1 1 0 SPX domain bZIP_1 PF00170.21 AAL63471.1 - 0.04 14.0 8.6 0.078 13.1 1.5 3.2 1 1 2 3 3 3 0 bZIP transcription factor Nsp1_C PF05064.13 AAL63471.1 - 0.04 13.7 2.7 0.093 12.5 1.2 1.9 1 1 1 2 2 2 0 Nsp1-like C-terminal region HAUS-augmin3 PF14932.6 AAL63471.1 - 0.043 13.4 2.3 0.051 13.1 2.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF16 PF01519.16 AAL63471.1 - 0.051 14.1 1.6 0.069 13.6 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 SF-assemblin PF06705.11 AAL63471.1 - 0.052 12.9 6.0 0.065 12.6 6.0 1.2 1 0 0 1 1 1 0 SF-assemblin/beta giardin ECM11 PF15463.6 AAL63471.1 - 0.056 14.0 5.7 0.078 13.6 2.6 2.0 1 1 1 2 2 2 0 Extracellular mutant protein 11 Fib_alpha PF08702.10 AAL63471.1 - 0.056 13.6 3.7 2.3 8.4 0.6 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family COG5 PF10392.9 AAL63471.1 - 0.057 13.6 3.9 0.21 11.7 3.9 1.8 1 1 0 1 1 1 0 Golgi transport complex subunit 5 Exonuc_VII_L PF02601.15 AAL63471.1 - 0.065 12.8 1.7 0.073 12.6 1.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF745 PF05335.13 AAL63471.1 - 0.066 12.9 1.0 0.08 12.7 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) SpoIIID PF12116.8 AAL63471.1 - 0.075 13.1 1.0 0.89 9.7 0.1 2.3 1 1 1 2 2 2 0 Stage III sporulation protein D Allexi_40kDa PF05549.11 AAL63471.1 - 0.076 12.5 1.3 0.095 12.2 1.3 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF1515 PF07439.11 AAL63471.1 - 0.077 13.0 3.8 0.16 12.0 3.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) Tup_N PF08581.10 AAL63471.1 - 0.079 13.3 5.8 0.11 12.8 4.7 1.8 1 1 2 3 3 3 0 Tup N-terminal TMF_TATA_bd PF12325.8 AAL63471.1 - 0.084 13.1 7.6 0.11 12.7 6.7 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF4795 PF16043.5 AAL63471.1 - 0.084 12.5 6.9 0.13 11.9 6.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF1319 PF07028.11 AAL63471.1 - 0.09 13.0 5.5 0.49 10.6 5.5 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1319) Prominin PF05478.11 AAL63471.1 - 0.093 10.7 3.0 0.1 10.6 3.0 1.0 1 0 0 1 1 1 0 Prominin DUF4407 PF14362.6 AAL63471.1 - 0.094 12.0 0.3 0.17 11.2 0.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) RmuC PF02646.16 AAL63471.1 - 0.1 11.7 4.0 0.78 8.8 0.8 1.9 1 1 1 2 2 2 0 RmuC family CCDC-167 PF15188.6 AAL63471.1 - 0.1 12.9 9.8 1.7 9.1 4.8 2.5 1 1 2 3 3 3 0 Coiled-coil domain-containing protein 167 betaPIX_CC PF16523.5 AAL63471.1 - 0.11 12.4 8.4 1.2 9.0 4.8 2.3 1 1 1 2 2 2 0 betaPIX coiled coil Uso1_p115_C PF04871.13 AAL63471.1 - 0.12 12.7 8.1 1 9.8 7.5 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF1451 PF07295.11 AAL63471.1 - 0.13 12.3 1.9 0.16 12.0 1.9 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain LMBR1 PF04791.16 AAL63471.1 - 0.13 11.1 0.6 0.14 11.1 0.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein FlaC_arch PF05377.11 AAL63471.1 - 0.14 12.5 5.1 3.7 8.0 5.1 2.6 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) Wtap PF17098.5 AAL63471.1 - 0.16 11.9 6.4 0.18 11.8 4.8 1.8 1 1 1 2 2 2 0 WTAP/Mum2p family Spc24 PF08286.11 AAL63471.1 - 0.16 12.2 4.3 0.28 11.4 4.1 1.6 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 MetOD2 PF18548.1 AAL63471.1 - 0.18 11.9 5.7 0.4 10.8 0.4 2.2 1 1 1 2 2 2 0 Metanogen output domain 2 YabA PF06156.13 AAL63471.1 - 0.19 12.4 4.9 0.55 10.9 4.8 1.9 1 1 0 1 1 1 0 Initiation control protein YabA XhlA PF10779.9 AAL63471.1 - 0.21 11.8 7.1 0.39 11.0 0.8 2.2 1 1 1 2 2 2 0 Haemolysin XhlA DUF4988 PF16378.5 AAL63471.1 - 0.24 11.1 3.6 5.9 6.5 0.5 2.7 1 1 1 2 2 2 0 Domain of unknown function DUF5446 PF17522.2 AAL63471.1 - 0.33 11.2 5.0 3.5 7.9 0.3 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5446) MutS_IV PF05190.18 AAL63471.1 - 0.34 11.3 4.6 1 9.7 2.3 2.5 1 1 2 3 3 3 0 MutS family domain IV CorA PF01544.18 AAL63471.1 - 0.49 9.7 5.4 0.6 9.4 5.4 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Tsc35 PF15079.6 AAL63471.1 - 0.57 9.7 7.2 3.2 7.3 5.8 1.9 1 1 0 1 1 1 0 Testis-specific protein 35 HalX PF08663.10 AAL63471.1 - 0.63 10.4 6.0 3.4 8.1 3.9 2.5 1 1 1 2 2 2 0 HalX domain Med21 PF11221.8 AAL63471.1 - 0.69 10.2 5.7 1.2 9.4 4.8 1.8 1 1 1 2 2 2 0 Subunit 21 of Mediator complex DUF848 PF05852.11 AAL63471.1 - 0.7 10.0 6.9 2.3 8.4 1.1 2.1 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) PMT_2 PF13231.6 AAL63474.1 - 0.023 14.9 5.8 0.025 14.8 5.8 1.0 1 0 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase CPP1-like PF11833.8 AAL63474.1 - 0.075 12.7 3.1 0.13 11.9 3.1 1.4 1 1 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DoxX_2 PF13564.6 AAL63474.1 - 5.8 7.1 12.0 6.5 6.9 3.3 2.2 1 1 1 2 2 2 0 DoxX-like family CstA PF02554.14 AAL63476.1 - 1.4e-103 346.7 26.1 1.4e-103 346.7 26.1 2.2 1 1 0 2 2 2 1 Carbon starvation protein CstA CstA_5TM PF13722.6 AAL63476.1 - 5.2e-19 68.7 12.6 5.2e-19 68.7 12.6 3.5 3 1 0 3 3 3 1 5TM C-terminal transporter carbon starvation CstA HrpJ PF07201.11 AAL63477.1 - 0.011 16.0 0.5 0.017 15.5 0.5 1.4 1 1 0 1 1 1 0 HrpJ-like domain ARL2_Bind_BART PF11527.8 AAL63477.1 - 0.047 13.8 0.3 0.073 13.2 0.3 1.2 1 0 0 1 1 1 0 The ARF-like 2 binding protein BART SbsC_C PF18058.1 AAL63477.1 - 0.052 13.8 0.1 0.071 13.4 0.1 1.2 1 0 0 1 1 1 0 SbsC C-terminal domain DisA-linker PF10635.9 AAL63477.1 - 0.053 13.3 0.2 0.059 13.1 0.2 1.1 1 0 0 1 1 1 0 DisA bacterial checkpoint controller linker region CSN8_PSD8_EIF3K PF10075.9 AAL63477.1 - 0.073 13.1 0.0 0.092 12.7 0.0 1.1 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family ArsA_ATPase PF02374.15 AAL63478.1 - 8.8e-65 218.9 0.0 4.7e-64 216.5 0.0 1.8 1 1 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 AAL63478.1 - 4.9e-13 49.4 0.0 7.9e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 AAL63478.1 - 1.1e-12 48.1 0.0 6.7e-12 45.6 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 AAL63478.1 - 5.7e-07 29.2 0.1 0.00014 21.4 0.0 2.3 2 0 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 AAL63478.1 - 1.3e-05 24.8 0.0 8.4e-05 22.1 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 AAL63478.1 - 0.00067 19.2 0.1 0.0013 18.3 0.1 1.4 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ AAA_26 PF13500.6 AAL63478.1 - 0.0013 18.6 0.4 0.015 15.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 AAL63478.1 - 0.0036 16.9 0.0 0.0065 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 AAL63478.1 - 0.011 15.2 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein ATP_bind_1 PF03029.17 AAL63478.1 - 0.014 15.2 0.3 0.22 11.3 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein IstB_IS21 PF01695.17 AAL63478.1 - 0.014 15.1 0.1 0.026 14.3 0.1 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein MeaB PF03308.16 AAL63478.1 - 0.014 14.4 0.1 0.025 13.5 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54 PF00448.22 AAL63478.1 - 0.023 14.3 0.0 0.17 11.5 0.1 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NACHT PF05729.12 AAL63478.1 - 0.028 14.3 0.2 0.054 13.4 0.2 1.4 1 0 0 1 1 1 0 NACHT domain APS_kinase PF01583.20 AAL63478.1 - 0.029 14.3 0.1 0.065 13.1 0.1 1.6 2 0 0 2 2 2 0 Adenylylsulphate kinase NTPase_1 PF03266.15 AAL63478.1 - 0.058 13.3 0.1 0.95 9.4 0.1 2.7 3 1 0 3 3 3 0 NTPase Zeta_toxin PF06414.12 AAL63478.1 - 0.095 12.0 0.0 0.25 10.6 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.22 AAL63478.1 - 0.14 11.3 0.2 0.23 10.6 0.2 1.3 1 0 0 1 1 1 0 NB-ARC domain VirC1 PF07015.11 AAL63478.1 - 0.19 11.0 0.1 0.32 10.3 0.1 1.3 1 0 0 1 1 1 0 VirC1 protein DUF4418 PF14387.6 AAL63481.1 - 0.014 15.6 1.0 0.019 15.2 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4418) CPBP PF02517.16 AAL63482.1 - 1.5e-11 44.5 1.7 1.5e-11 44.5 1.7 2.6 2 1 1 3 3 3 2 CPBP intramembrane metalloprotease LysE PF01810.18 AAL63483.1 - 0.011 15.2 1.6 0.014 14.9 1.6 1.2 1 0 0 1 1 1 0 LysE type translocator ProSAAS PF07259.12 AAL63486.1 - 0.068 13.1 0.0 0.072 13.0 0.0 1.1 1 0 0 1 1 1 0 ProSAAS precursor CTP_transf_like PF01467.26 AAL63487.1 - 2.1e-14 53.9 0.0 1.3e-13 51.4 0.0 1.9 1 1 0 1 1 1 1 Cytidylyltransferase-like ATP-sulfurylase PF01747.17 AAL63487.1 - 0.063 12.7 0.0 2.1 7.8 0.0 2.1 2 0 0 2 2 2 0 ATP-sulfurylase HIGH_NTase1 PF05636.11 AAL63487.1 - 0.16 11.1 0.0 4.8 6.3 0.0 2.0 2 0 0 2 2 2 0 HIGH Nucleotidyl Transferase tRNA-synt_2d PF01409.20 AAL63488.1 - 2.1e-79 266.5 0.0 2.7e-79 266.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA_synthFbeta PF17759.1 AAL63488.1 - 3.5e-08 33.2 0.0 3.9e-07 29.7 0.0 2.1 2 0 0 2 2 2 1 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 AAL63488.1 - 4e-07 29.4 0.1 0.0051 15.9 0.0 3.6 4 0 0 4 4 4 2 tRNA synthetases class II (D, K and N) HBS1_N PF08938.10 AAL63488.1 - 0.015 15.6 0.2 0.67 10.3 0.0 3.0 3 0 0 3 3 3 0 HBS1 N-terminus MAF_flag10 PF01973.18 AAL63488.1 - 0.072 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF115 RHH_1 PF01402.21 AAL63489.1 - 3.6e-13 48.9 0.1 5.8e-13 48.3 0.1 1.4 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family RHH_8 PF17723.1 AAL63489.1 - 0.00071 19.7 0.0 0.0013 18.9 0.0 1.5 1 1 0 1 1 1 1 Ribbon-Helix-Helix transcriptional regulator family Rnk_N PF14760.6 AAL63490.1 - 0.052 14.0 0.3 0.65 10.5 0.1 2.2 1 1 1 2 2 2 0 Rnk N-terminus DUF1512 PF07431.12 AAL63491.1 - 7.9e-132 439.6 0.6 9.1e-132 439.4 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1512) Nucleos_tra2_N PF01773.20 AAL63493.1 - 0.0036 17.9 0.2 0.0036 17.9 0.2 2.2 1 1 1 2 2 2 1 Na+ dependent nucleoside transporter N-terminus ZYG-11_interact PF05884.12 AAL63493.1 - 0.012 15.0 2.4 0.014 14.8 2.4 1.0 1 0 0 1 1 1 0 Interactor of ZYG-11 DUF5592 PF17332.2 AAL63493.1 - 0.24 11.9 3.7 0.27 11.8 1.8 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5592) ABC2_membrane_2 PF12679.7 AAL63493.1 - 1.5 8.0 8.7 1.9 7.7 8.7 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4407 PF14362.6 AAL63494.1 - 0.00018 21.0 2.2 0.00018 21.0 2.2 3.4 1 1 2 3 3 3 1 Domain of unknown function (DUF4407) IFT57 PF10498.9 AAL63494.1 - 0.00028 20.0 1.0 0.00028 20.0 1.0 4.0 1 1 3 4 4 4 2 Intra-flagellar transport protein 57 Baculo_PEP_C PF04513.12 AAL63494.1 - 0.0012 18.9 30.2 0.017 15.2 5.7 5.6 1 1 4 5 5 5 3 Baculovirus polyhedron envelope protein, PEP, C terminus Uso1_p115_C PF04871.13 AAL63494.1 - 0.0026 18.1 5.4 0.0026 18.1 5.4 5.1 1 1 3 5 5 5 1 Uso1 / p115 like vesicle tethering protein, C terminal region DHR10 PF18595.1 AAL63494.1 - 0.0059 16.7 20.2 0.0059 16.7 20.2 5.9 1 1 5 6 6 5 4 Designed helical repeat protein 10 domain Mce4_CUP1 PF11887.8 AAL63494.1 - 0.0059 16.1 14.8 1.4 8.4 1.3 3.6 1 1 2 4 4 4 2 Cholesterol uptake porter CUP1 of Mce4, putative Sec34 PF04136.15 AAL63494.1 - 0.0071 16.2 35.3 0.2 11.5 7.1 5.5 1 1 3 5 5 5 2 Sec34-like family CheZ PF04344.13 AAL63494.1 - 0.0075 16.2 3.3 0.0075 16.2 3.3 4.6 1 1 3 4 4 3 1 Chemotaxis phosphatase, CheZ DUF1664 PF07889.12 AAL63494.1 - 0.011 15.8 0.9 0.011 15.8 0.9 5.4 1 1 5 6 6 6 0 Protein of unknown function (DUF1664) AAA_13 PF13166.6 AAL63494.1 - 0.022 13.4 45.9 0.064 11.9 23.1 3.0 1 1 3 4 4 4 0 AAA domain DUF3584 PF12128.8 AAL63494.1 - 0.023 12.2 51.3 0.0076 13.8 19.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Spc7 PF08317.11 AAL63494.1 - 0.025 13.5 69.3 0.21 10.4 20.7 4.7 1 1 5 6 6 6 0 Spc7 kinetochore protein FPP PF05911.11 AAL63494.1 - 0.033 12.4 47.6 0.13 10.4 37.2 2.2 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil MerR-DNA-bind PF09278.11 AAL63494.1 - 0.037 14.5 8.0 0.037 14.5 8.0 7.3 5 3 4 9 9 9 0 MerR, DNA binding Spectrin PF00435.21 AAL63494.1 - 0.043 14.3 49.3 0.92 10.0 0.5 5.6 1 1 5 6 6 6 0 Spectrin repeat NPV_P10 PF05531.12 AAL63494.1 - 0.043 14.3 23.2 0.34 11.4 3.1 5.3 1 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 AAL63494.1 - 0.11 12.7 24.5 4.4 7.6 2.7 5.7 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 AAL63494.1 - 0.25 11.3 47.7 0.021 14.8 5.9 4.8 2 2 2 4 4 4 0 Laminin Domain II Vip3A_N PF12495.8 AAL63494.1 - 0.49 10.3 7.4 2.6 7.9 0.3 2.7 2 1 1 3 3 3 0 Vegetative insecticide protein 3A N terminal FUSC PF04632.12 AAL63494.1 - 0.67 8.4 39.5 0.62 8.5 2.0 3.1 1 1 2 3 3 3 0 Fusaric acid resistance protein family APG17 PF04108.12 AAL63494.1 - 0.9 8.6 43.0 0.29 10.2 3.4 4.0 1 1 4 5 5 5 0 Autophagy protein Apg17 EzrA PF06160.12 AAL63494.1 - 1.5 6.9 45.8 0.029 12.5 4.8 3.6 1 1 2 3 3 3 0 Septation ring formation regulator, EzrA Exonuc_VII_L PF02601.15 AAL63494.1 - 2.1 7.8 49.9 9.5 5.7 18.6 3.3 1 1 1 2 2 1 0 Exonuclease VII, large subunit PI3K_P85_iSH2 PF16454.5 AAL63494.1 - 3.6 7.2 43.7 48 3.5 16.4 4.2 1 1 1 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4279 PF14106.6 AAL63494.1 - 4.4 7.5 9.3 38 4.5 0.1 4.7 3 2 0 3 3 3 0 Domain of unknown function (DUF4279) BLOC1_2 PF10046.9 AAL63494.1 - 5 7.5 47.5 0.12 12.7 1.8 6.3 2 1 6 8 8 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MCPsignal PF00015.21 AAL63494.1 - 5.3 6.8 23.4 0.2 11.4 3.3 3.9 1 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF4200 PF13863.6 AAL63494.1 - 6.4 7.2 73.3 0.89 10.0 13.5 5.0 1 1 2 4 4 4 0 Domain of unknown function (DUF4200) Mod_r PF07200.13 AAL63494.1 - 8.4 6.5 59.4 1.3 9.2 19.3 5.4 1 1 5 6 6 4 0 Modifier of rudimentary (Mod(r)) protein Seryl_tRNA_N PF02403.22 AAL63495.1 - 6.9e-05 23.0 1.0 0.00011 22.4 1.0 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain MinC_N PF05209.13 AAL63495.1 - 0.00027 20.8 0.6 0.00033 20.6 0.6 1.1 1 0 0 1 1 1 1 Septum formation inhibitor MinC, N-terminal domain TSC22 PF01166.18 AAL63495.1 - 0.0041 17.4 0.7 0.86 10.0 0.0 2.4 2 0 0 2 2 2 1 TSC-22/dip/bun family Cnn_1N PF07989.11 AAL63495.1 - 0.0081 16.3 0.1 0.019 15.1 0.1 1.5 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 Cast PF10174.9 AAL63495.1 - 0.0082 14.4 0.2 0.009 14.3 0.2 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone GAS PF13851.6 AAL63495.1 - 0.0085 15.5 0.2 0.01 15.2 0.2 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding HrpB7 PF09486.10 AAL63495.1 - 0.0098 16.3 2.8 0.0098 16.3 2.8 1.3 1 1 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) TMF_DNA_bd PF12329.8 AAL63495.1 - 0.011 15.7 1.0 0.037 14.0 0.8 1.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.15 AAL63495.1 - 0.016 14.9 0.5 0.029 14.1 0.5 1.4 1 0 0 1 1 1 0 Septum formation initiator NPV_P10 PF05531.12 AAL63495.1 - 0.019 15.4 1.5 0.099 13.1 1.5 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.10 AAL63495.1 - 0.021 15.0 1.2 0.12 12.5 1.4 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family CHASE3 PF05227.13 AAL63495.1 - 0.022 14.7 2.5 0.027 14.4 2.5 1.2 1 0 0 1 1 1 0 CHASE3 domain Spc7 PF08317.11 AAL63495.1 - 0.027 13.3 0.8 0.029 13.3 0.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2203 PF09969.9 AAL63495.1 - 0.029 15.1 0.7 0.037 14.7 0.7 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) ADIP PF11559.8 AAL63495.1 - 0.031 14.4 0.5 0.037 14.1 0.5 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF948 PF06103.11 AAL63495.1 - 0.032 14.5 0.4 0.048 13.9 0.4 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Syntaxin PF00804.25 AAL63495.1 - 0.033 13.9 0.8 0.037 13.7 0.8 1.2 1 0 0 1 1 1 0 Syntaxin DUF4201 PF13870.6 AAL63495.1 - 0.034 13.9 0.3 0.062 13.0 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Occludin_ELL PF07303.13 AAL63495.1 - 0.037 14.7 0.0 0.051 14.3 0.0 1.3 1 0 0 1 1 1 0 Occludin homology domain Mod_r PF07200.13 AAL63495.1 - 0.038 14.1 0.2 0.05 13.7 0.1 1.3 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF4795 PF16043.5 AAL63495.1 - 0.039 13.6 0.1 0.045 13.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) DUF677 PF05055.12 AAL63495.1 - 0.042 12.7 1.8 0.054 12.4 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) ZapB PF06005.12 AAL63495.1 - 0.048 14.1 3.3 0.088 13.3 3.3 1.7 1 1 0 1 1 1 0 Cell division protein ZapB SlyX PF04102.12 AAL63495.1 - 0.054 14.1 2.4 0.12 13.0 0.4 2.3 2 1 0 2 2 2 0 SlyX DivIVA PF05103.13 AAL63495.1 - 0.061 13.4 2.6 0.08 13.0 2.6 1.2 1 0 0 1 1 1 0 DivIVA protein Noc2 PF03715.13 AAL63495.1 - 0.065 12.5 0.1 0.068 12.4 0.1 1.2 1 0 0 1 1 1 0 Noc2p family SKA2 PF16740.5 AAL63495.1 - 0.075 12.8 2.4 0.21 11.4 0.7 2.1 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 TPR_MLP1_2 PF07926.12 AAL63495.1 - 0.08 13.0 2.5 0.13 12.4 2.3 1.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein COG7 PF10191.9 AAL63495.1 - 0.091 11.0 1.1 0.1 10.8 1.1 1.0 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) APG6_N PF17675.1 AAL63495.1 - 0.091 13.3 0.9 0.11 13.0 0.9 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Syntaxin_2 PF14523.6 AAL63495.1 - 0.095 13.1 0.2 0.15 12.4 0.2 1.4 1 1 0 1 1 1 0 Syntaxin-like protein Nas2_N PF18265.1 AAL63495.1 - 0.1 12.5 0.5 0.31 11.0 0.0 2.0 3 0 0 3 3 2 0 Nas2 N_terminal domain CCDC92 PF14916.6 AAL63495.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain of unknown function Val_tRNA-synt_C PF10458.9 AAL63495.1 - 0.14 12.5 4.0 0.32 11.3 4.0 1.9 1 1 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm Spc24 PF08286.11 AAL63495.1 - 0.19 12.0 0.7 0.26 11.6 0.7 1.3 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DUF3138 PF11336.8 AAL63495.1 - 0.21 10.1 0.2 0.23 10.0 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) LPP PF04728.13 AAL63495.1 - 0.24 11.8 4.4 1.8 9.0 4.4 2.0 1 1 0 1 1 1 0 Lipoprotein leucine-zipper COG2 PF06148.11 AAL63495.1 - 1.1 9.3 4.3 3.3 7.8 0.4 2.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Csm1_N PF18504.1 AAL63495.1 - 2.2 8.7 6.5 1.9 8.9 1.1 2.5 1 1 0 2 2 2 0 Csm1 N-terminal domain PaRep2a PF07903.11 AAL63496.1 - 4.1e-19 68.6 0.3 4.4e-19 68.5 0.3 1.0 1 0 0 1 1 1 1 PaRep2a protein ApoA-II PF04711.13 AAL63500.1 - 0.14 12.3 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Apolipoprotein A-II (ApoA-II) EVE PF01878.18 AAL63501.1 - 1.5e-07 31.5 0.0 1.6e-07 31.4 0.0 1.0 1 0 0 1 1 1 1 EVE domain DXPR_C PF13288.6 AAL63502.1 - 0.011 16.0 0.0 0.036 14.3 0.0 2.0 2 1 1 3 3 3 0 DXP reductoisomerase C-terminal domain TF_Zn_Ribbon PF08271.12 AAL63503.1 - 0.00028 20.3 3.0 0.049 13.2 0.1 2.2 2 0 0 2 2 2 2 TFIIB zinc-binding Zn_Tnp_IS1595 PF12760.7 AAL63503.1 - 0.00037 20.4 1.9 0.00057 19.8 1.9 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.10 AAL63503.1 - 0.0016 18.5 3.8 0.17 12.0 0.7 2.2 2 0 0 2 2 2 2 Zinc ribbon domain zf-TFIIB PF13453.6 AAL63503.1 - 0.0019 17.5 1.7 0.0033 16.7 1.7 1.4 1 1 0 1 1 1 1 Transcription factor zinc-finger zf-ribbon_3 PF13248.6 AAL63503.1 - 0.0039 16.5 3.7 0.11 11.9 0.1 2.3 2 0 0 2 2 2 1 zinc-ribbon domain DUF3268 PF11672.8 AAL63503.1 - 0.0064 16.8 1.4 0.0067 16.7 1.4 1.1 1 0 0 1 1 1 1 zinc-finger-containing domain DZR PF12773.7 AAL63503.1 - 0.0074 16.3 0.4 0.0099 15.9 0.4 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-IS66 PF13005.7 AAL63503.1 - 0.0083 16.5 2.1 0.52 10.7 2.9 2.3 1 1 1 2 2 2 1 zinc-finger binding domain of transposase IS66 Rubredoxin_2 PF18073.1 AAL63503.1 - 0.013 15.2 6.5 0.039 13.7 1.3 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain HypA PF01155.19 AAL63503.1 - 0.038 14.0 1.5 0.88 9.6 0.1 2.0 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TFIIS_C PF01096.18 AAL63503.1 - 0.038 13.8 2.5 3.7 7.5 0.2 2.1 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) DUF35_N PF12172.8 AAL63503.1 - 0.039 13.8 2.2 2.4 8.1 0.1 2.2 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Lar_restr_allev PF14354.6 AAL63503.1 - 0.058 13.8 2.5 0.084 13.3 2.5 1.4 1 1 0 1 1 1 0 Restriction alleviation protein Lar zf-LITAF-like PF10601.9 AAL63503.1 - 0.061 13.6 1.0 9.8 6.5 0.2 2.1 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain Terminase_GpA PF05876.12 AAL63503.1 - 0.1 11.1 0.3 0.11 11.0 0.3 1.0 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) OrfB_Zn_ribbon PF07282.11 AAL63503.1 - 0.13 12.2 2.1 0.43 10.5 2.1 1.8 1 1 0 1 1 1 0 Putative transposase DNA-binding domain zf-ZPR1 PF03367.13 AAL63503.1 - 0.14 12.0 0.2 0.15 11.9 0.2 1.1 1 0 0 1 1 1 0 ZPR1 zinc-finger domain FdhE PF04216.12 AAL63503.1 - 0.19 11.6 2.8 0.17 11.7 2.8 1.0 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation zf-ISL3 PF14690.6 AAL63503.1 - 0.2 12.3 5.4 0.75 10.5 0.4 2.2 1 1 2 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zinc_ribbon_2 PF13240.6 AAL63503.1 - 0.22 11.3 7.4 0.4 10.5 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Hexapep PF00132.24 AAL63504.1 - 1.2e-27 94.5 28.7 1.8e-08 33.8 0.2 5.5 5 1 1 6 6 6 5 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AAL63504.1 - 5.7e-20 70.8 17.6 5.2e-07 29.3 3.5 6.2 5 1 1 6 6 6 4 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 AAL63504.1 - 0.13 10.4 1.2 0.22 9.6 0.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4954) Peptidase_M42 PF05343.14 AAL63505.1 - 2.8e-87 292.5 0.0 3.3e-87 292.2 0.0 1.0 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.28 AAL63505.1 - 3.7e-07 30.0 0.2 8.5e-07 28.9 0.2 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M18 PF02127.15 AAL63505.1 - 0.00013 21.0 0.0 0.0019 17.1 0.0 2.0 1 1 1 2 2 2 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M28 PF04389.17 AAL63505.1 - 0.0075 16.0 0.0 0.05 13.3 0.0 2.2 2 1 0 2 2 2 1 Peptidase family M28 PNP_UDP_1 PF01048.20 AAL63506.1 - 8.9e-34 116.8 2.8 1.1e-33 116.5 2.8 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily DUF676 PF05057.14 AAL63506.1 - 0.08 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Lys_export PF03956.13 AAL63508.1 - 3e-36 124.7 15.7 3e-36 124.7 15.7 2.0 2 0 0 2 2 2 1 Lysine exporter LysO Flavoprotein PF02441.19 AAL63510.1 - 1.1e-26 93.5 0.1 1.3e-26 93.2 0.1 1.1 1 0 0 1 1 1 1 Flavoprotein RHH_1 PF01402.21 AAL63512.1 - 0.00035 20.4 0.6 0.00035 20.4 0.6 1.5 2 0 0 2 2 2 1 Ribbon-helix-helix protein, copG family RHH_8 PF17723.1 AAL63512.1 - 0.0046 17.1 0.0 0.0054 16.9 0.0 1.1 1 0 0 1 1 1 1 Ribbon-Helix-Helix transcriptional regulator family GerD PF17898.1 AAL63512.1 - 0.012 15.6 0.0 0.015 15.2 0.0 1.1 1 0 0 1 1 1 0 Spore germination GerD central core domain VapB_antitoxin PF09957.9 AAL63512.1 - 0.012 15.5 0.2 0.018 15.0 0.2 1.3 1 0 0 1 1 1 0 Bacterial antitoxin of type II TA system, VapB HicB_lk_antitox PF15919.5 AAL63512.1 - 0.22 11.7 0.0 0.3 11.2 0.0 1.3 1 1 0 1 1 1 0 HicB_like antitoxin of bacterial toxin-antitoxin system Met_10 PF02475.16 AAL63513.1 - 6.8e-55 185.9 0.0 8.2e-55 185.6 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Methyltr_RsmB-F PF01189.17 AAL63513.1 - 0.00012 21.8 0.0 0.0002 21.1 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F TRM PF02005.16 AAL63513.1 - 0.00018 20.8 0.0 0.00024 20.4 0.0 1.2 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase PrmA PF06325.13 AAL63513.1 - 0.0018 17.7 0.0 0.0026 17.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 AAL63513.1 - 0.0053 16.4 0.0 0.0091 15.7 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 ADH_zinc_N PF00107.26 AAL63513.1 - 0.063 13.3 0.0 0.19 11.7 0.0 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase MTS PF05175.14 AAL63513.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain DUF2153 PF09921.9 AAL63514.1 - 4.5e-46 155.7 0.7 5.5e-46 155.4 0.7 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2153) CorA PF01544.18 AAL63514.1 - 0.0026 17.1 0.6 0.0032 16.8 0.6 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF3891 PF13030.6 AAL63514.1 - 0.023 14.5 0.1 0.028 14.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3891) Glyco_H_20C_C PF18088.1 AAL63514.1 - 0.025 14.4 1.7 0.052 13.4 1.7 1.5 1 0 0 1 1 1 0 Glycoside Hydrolase 20C C-terminal domain COG5 PF10392.9 AAL63514.1 - 0.038 14.2 0.3 1.2 9.3 0.2 2.1 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF16 PF01519.16 AAL63514.1 - 0.05 14.1 0.1 0.088 13.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 RPW8 PF05659.11 AAL63514.1 - 0.052 13.2 1.1 0.86 9.3 0.2 2.1 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF4635 PF15466.6 AAL63514.1 - 0.078 12.5 5.5 0.31 10.5 3.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4635) THOC7 PF05615.13 AAL63514.1 - 0.09 13.1 0.8 0.54 10.5 0.4 2.0 2 0 0 2 2 2 0 Tho complex subunit 7 DUF1912 PF08930.10 AAL63514.1 - 0.13 12.5 1.4 2 8.6 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1912) Herpes_UL33 PF03581.13 AAL63514.1 - 0.15 12.5 0.0 0.86 10.0 0.0 2.1 1 1 0 1 1 1 0 Herpesvirus UL33-like protein DUF99 PF01949.16 AAL63514.1 - 0.15 11.5 0.6 2.6 7.4 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF99 KR PF08659.10 AAL63514.1 - 0.2 11.6 0.1 0.55 10.1 0.0 1.7 1 1 1 2 2 2 0 KR domain SIS PF01380.22 AAL63515.1 - 4.2e-17 62.2 0.1 7.9e-17 61.3 0.1 1.4 1 0 0 1 1 1 1 SIS domain SIS_2 PF13580.6 AAL63515.1 - 3.6e-11 43.2 1.9 6.7e-07 29.4 0.9 2.4 1 1 1 2 2 2 2 SIS domain LigB PF02900.18 AAL63515.1 - 0.018 14.2 0.0 0.027 13.6 0.0 1.5 2 0 0 2 2 2 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase DSPc PF00782.20 AAL63515.1 - 0.02 14.7 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain PRMT5 PF05185.16 AAL63515.1 - 0.024 14.5 2.5 2.5 7.9 0.1 2.9 2 1 1 3 3 3 0 PRMT5 arginine-N-methyltransferase AdoMet_dc PF02675.15 AAL63516.1 - 9.1e-36 122.3 0.0 1e-35 122.2 0.0 1.0 1 0 0 1 1 1 1 S-adenosylmethionine decarboxylase TF_Zn_Ribbon PF08271.12 AAL63518.1 - 0.00021 20.7 1.6 0.0007 19.0 1.6 1.7 1 1 0 1 1 1 1 TFIIB zinc-binding DUF1922 PF09082.10 AAL63518.1 - 0.0007 19.8 1.1 0.00075 19.7 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1922) zf-ribbon_3 PF13248.6 AAL63518.1 - 0.0018 17.6 0.5 0.064 12.7 0.1 2.2 2 0 0 2 2 2 1 zinc-ribbon domain DZR PF12773.7 AAL63518.1 - 0.0026 17.8 0.3 0.0038 17.2 0.3 1.3 1 0 0 1 1 1 1 Double zinc ribbon CpXC PF14353.6 AAL63518.1 - 0.0072 16.4 0.1 0.11 12.6 0.0 2.0 2 0 0 2 2 2 1 CpXC protein Zn-ribbon_8 PF09723.10 AAL63518.1 - 0.0075 16.4 0.3 0.013 15.6 0.3 1.4 1 0 0 1 1 1 1 Zinc ribbon domain HypA PF01155.19 AAL63518.1 - 0.012 15.7 1.1 0.014 15.4 0.9 1.3 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_ribbon_SprT PF17283.2 AAL63518.1 - 0.015 15.2 0.9 0.025 14.5 0.9 1.4 1 0 0 1 1 1 0 SprT-like zinc ribbon domain NOB1_Zn_bind PF08772.11 AAL63518.1 - 0.017 15.3 0.2 0.018 15.2 0.2 1.2 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zinc_ribbon_2 PF13240.6 AAL63518.1 - 0.017 14.8 5.0 0.37 10.6 5.1 2.1 1 1 0 1 1 1 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 AAL63518.1 - 0.022 14.7 0.3 0.026 14.5 0.3 1.2 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf_UBZ PF18439.1 AAL63518.1 - 0.03 13.9 0.3 5.2 6.7 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DUF1610 PF07754.11 AAL63518.1 - 0.042 13.8 0.4 0.09 12.8 0.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1610) zf-C3HC4_4 PF15227.6 AAL63518.1 - 0.047 13.8 0.6 0.064 13.4 0.6 1.2 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-ISL3 PF14690.6 AAL63518.1 - 0.059 14.1 3.9 0.32 11.7 0.3 2.3 1 1 1 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zinc_ribbon_4 PF13717.6 AAL63518.1 - 0.066 13.1 0.8 3.3 7.7 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain FUR PF01475.19 AAL63518.1 - 0.11 12.7 0.4 0.66 10.1 0.0 1.9 1 1 1 2 2 2 0 Ferric uptake regulator family DUF3268 PF11672.8 AAL63518.1 - 0.11 12.9 1.4 0.53 10.6 1.4 1.9 1 1 0 1 1 1 0 zinc-finger-containing domain MRNIP PF15749.5 AAL63518.1 - 0.11 13.2 0.1 0.12 13.0 0.1 1.1 1 0 0 1 1 1 0 MRN-interacting protein zf-LITAF-like PF10601.9 AAL63518.1 - 0.17 12.2 2.0 1 9.7 0.1 2.0 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain Aconitase PF00330.20 AAL63519.1 - 2.5e-167 557.6 0.0 2.9e-167 557.3 0.0 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 AAL63519.1 - 3.4e-36 124.5 0.0 5.4e-36 123.8 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain HTH_38 PF13936.6 AAL63519.1 - 0.11 12.2 0.0 1.8 8.4 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain ESPR PF13018.6 AAL63520.1 - 0.042 13.7 0.0 0.069 13.0 0.0 1.5 1 0 0 1 1 1 0 Extended Signal Peptide of Type V secretion system Nucleoporin_FG2 PF15967.5 AAL63520.1 - 0.13 10.7 0.4 0.15 10.6 0.4 1.0 1 0 0 1 1 1 0 Nucleoporin FG repeated region FAM165 PF14981.6 AAL63520.1 - 6.1 6.7 7.8 4.7 7.1 1.2 2.5 2 0 0 2 2 2 0 FAM165 family TIM PF00121.18 AAL63521.1 - 3.8e-11 42.8 0.1 2.6e-10 40.1 0.0 1.8 1 1 1 2 2 2 1 Triosephosphate isomerase ThiG PF05690.14 AAL63521.1 - 3.1e-06 26.7 1.6 3.4e-06 26.5 0.2 1.7 1 1 0 1 1 1 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 AAL63521.1 - 0.0017 17.8 0.0 0.0046 16.4 0.0 1.7 1 0 0 1 1 1 1 Histidine biosynthesis protein NMO PF03060.15 AAL63521.1 - 0.0054 16.2 1.0 0.0054 16.2 1.0 2.0 1 1 0 2 2 2 1 Nitronate monooxygenase IGPS PF00218.21 AAL63521.1 - 0.0059 15.8 0.0 0.011 14.9 0.0 1.6 1 1 0 1 1 1 1 Indole-3-glycerol phosphate synthase FMN_dh PF01070.18 AAL63521.1 - 0.011 14.8 1.7 0.015 14.3 0.3 1.8 2 1 0 2 2 2 0 FMN-dependent dehydrogenase Hydrolase PF00702.26 AAL63521.1 - 0.041 14.2 0.6 0.098 12.9 0.6 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase G8 PF10162.9 AAL63523.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 G8 domain Ribosomal_S6e PF01092.19 AAL63524.1 - 1.9e-29 102.1 0.0 2.4e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6e AsnC_trans_reg PF01037.21 AAL63525.1 - 2.5e-15 56.2 0.1 2.8e-15 56.1 0.1 1.0 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain GTP_EFTU_D4 PF14578.6 AAL63529.1 - 8e-36 121.8 4.1 8e-36 121.8 4.1 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 4 GTP_EFTU PF00009.27 AAL63529.1 - 5.5e-27 94.6 0.0 2.2e-26 92.6 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 AAL63529.1 - 3e-17 62.7 0.1 6.6e-17 61.5 0.1 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 AAL63529.1 - 2.2e-10 40.8 8.1 4.5e-08 33.4 0.2 2.8 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 AAL63529.1 - 6.9e-05 22.9 0.0 0.00016 21.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF1905 PF08922.11 AAL63529.1 - 0.057 13.5 0.2 0.54 10.4 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1905) Roc PF08477.13 AAL63529.1 - 0.08 13.2 0.0 0.24 11.6 0.0 1.8 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 AAL63529.1 - 0.14 11.9 0.0 0.44 10.3 0.0 1.8 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation PaRep2b PF07775.11 AAL63530.1 - 1e-74 251.9 0.4 1.1e-74 251.8 0.4 1.0 1 0 0 1 1 1 1 PaRep2b protein PaREP1 PF05942.11 AAL63531.1 - 4.1e-28 97.6 2.6 5.2e-28 97.3 2.6 1.1 1 0 0 1 1 1 1 Archaeal PaREP1/PaREP8 family HEPN PF05168.14 AAL63531.1 - 0.032 14.4 1.0 0.077 13.1 1.0 1.7 1 1 0 1 1 1 0 HEPN domain Thioredoxin_3 PF13192.6 AAL63531.1 - 0.15 12.2 0.1 0.28 11.2 0.1 1.4 1 0 0 1 1 1 0 Thioredoxin domain Cren7 PF11520.8 AAL63532.1 - 2.9e-24 84.8 1.9 3.2e-24 84.6 1.9 1.0 1 0 0 1 1 1 1 Chromatin protein Cren7 UPF0122 PF04297.14 AAL63533.1 - 0.0011 19.2 0.2 0.0018 18.5 0.2 1.4 1 0 0 1 1 1 1 Putative helix-turn-helix protein, YlxM / p13 like CBS PF00571.28 AAL63534.1 - 2.2e-22 79.3 2.7 3.6e-10 40.1 0.2 2.2 2 0 0 2 2 2 2 CBS domain GGDEF_2 PF17853.1 AAL63534.1 - 0.046 14.0 0.1 0.087 13.1 0.1 1.5 1 1 0 1 1 1 0 GGDEF-like domain Glyco_hydro_67M PF07488.12 AAL63534.1 - 0.06 12.4 0.0 0.069 12.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 middle domain Clp_N PF02861.20 AAL63536.1 - 0.13 12.5 0.0 1.8 8.7 0.0 2.0 2 0 0 2 2 2 0 Clp amino terminal domain, pathogenicity island component Presenilin PF01080.17 AAL63537.1 - 2.4e-05 23.3 27.2 0.002 17.0 13.9 2.1 2 0 0 2 2 2 2 Presenilin Translin PF01997.16 AAL63538.1 - 6.4e-14 52.4 1.0 1.3e-12 48.1 1.0 2.0 1 1 0 1 1 1 1 Translin family ABC_tran_CTD PF16326.5 AAL63538.1 - 0.008 16.4 0.9 0.017 15.3 0.9 1.6 1 0 0 1 1 1 1 ABC transporter C-terminal domain DUF1570 PF07607.11 AAL63538.1 - 0.073 13.4 0.1 0.16 12.2 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1570) MbeD_MobD PF04899.12 AAL63538.1 - 0.11 12.7 0.3 2 8.6 0.1 2.7 2 1 1 3 3 3 0 MbeD/MobD like DUF4201 PF13870.6 AAL63538.1 - 0.21 11.3 2.8 0.14 11.8 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DivIC PF04977.15 AAL63538.1 - 2.1 8.2 5.3 3.8 7.4 0.1 2.9 2 1 1 3 3 3 0 Septum formation initiator Amidase PF01425.21 AAL63539.1 - 6.8e-84 282.4 6.3 6.4e-83 279.2 6.3 1.9 1 1 0 1 1 1 1 Amidase Lactamase_B PF00753.27 AAL63540.1 - 2.1e-18 67.0 7.7 8.7e-18 65.0 7.7 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AAL63540.1 - 1.2e-05 25.0 0.4 1.8e-05 24.3 0.4 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 AAL63540.1 - 5.7e-05 23.1 0.0 7.8e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain fn3_6 PF17766.1 AAL63541.1 - 0.085 13.0 0.2 0.54 10.5 0.0 2.4 2 1 0 2 2 2 0 Fibronectin type-III domain ChitinaseA_N PF08329.10 AAL63541.1 - 0.14 11.8 0.4 0.83 9.3 0.0 2.4 3 0 0 3 3 3 0 Chitinase A, N-terminal domain DUF2505 PF10698.9 AAL63541.1 - 0.3 11.2 1.9 0.73 9.9 1.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2505) Ig_3 PF13927.6 AAL63542.1 - 0.024 15.2 0.1 1.7 9.3 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin domain Cupredoxin_1 PF13473.6 AAL63542.1 - 0.049 13.8 0.0 1.1 9.4 0.0 2.1 2 0 0 2 2 2 0 Cupredoxin-like domain Motile_Sperm PF00635.26 AAL63542.1 - 0.12 12.3 0.1 2.6 8.0 0.0 2.2 2 0 0 2 2 2 0 MSP (Major sperm protein) domain DUF5374 PF17344.2 AAL63542.1 - 0.18 11.8 0.4 5.3 7.0 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5374) Gram_pos_anchor PF00746.21 AAL63543.1 - 0.02 14.8 0.7 0.031 14.2 0.7 1.3 1 0 0 1 1 1 0 LPXTG cell wall anchor motif DUF11 PF01345.18 AAL63543.1 - 0.027 14.8 2.0 0.035 14.4 1.1 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF11 DUF3040 PF11239.8 AAL63544.1 - 0.025 14.8 0.2 0.049 13.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) TPR_2 PF07719.17 AAL63544.1 - 0.24 11.6 4.6 1.6 9.0 4.6 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 AAL63544.1 - 0.3 11.0 4.2 4.6 7.2 4.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2892 PF11127.8 AAL63544.1 - 0.63 10.1 4.7 1.1 9.3 4.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2892) TPR_8 PF13181.6 AAL63544.1 - 0.94 9.9 3.4 0.97 9.8 1.9 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DSPc PF00782.20 AAL63545.1 - 3.3e-12 46.4 0.0 4e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 AAL63545.1 - 2.5e-06 27.2 0.0 3.1e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 AAL63545.1 - 2.8e-05 24.3 0.0 5.2e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate CDKN3 PF05706.12 AAL63545.1 - 0.0081 15.8 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.6 AAL63545.1 - 0.096 12.6 0.0 0.43 10.5 0.0 1.9 1 1 0 1 1 1 0 Tyrosine phosphatase family DsbD PF02683.15 AAL63546.1 - 1.8e-13 50.9 19.2 2.3e-12 47.3 19.2 2.5 1 1 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region Thioredoxin_2 PF13098.6 AAL63546.1 - 7.5e-05 23.1 0.0 0.00023 21.6 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 AAL63546.1 - 0.0075 16.4 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Lactamase_B PF00753.27 AAL63547.1 - 7.6e-29 101.1 0.7 1.1e-28 100.6 0.7 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AAL63547.1 - 0.00031 20.3 0.0 0.00044 19.8 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DAO PF01266.24 AAL63549.1 - 5.9e-13 49.1 3.3 3.6e-10 39.9 3.3 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 AAL63549.1 - 1.8e-07 30.7 0.0 0.00056 19.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AAL63549.1 - 0.0027 17.9 0.3 0.0061 16.8 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 AAL63549.1 - 0.074 12.3 0.1 0.14 11.3 0.1 1.5 2 0 0 2 2 2 0 FAD binding domain RHH_1 PF01402.21 AAL63550.1 - 2e-12 46.6 0.0 2.4e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family VapB_antitoxin PF09957.9 AAL63550.1 - 0.0012 18.8 0.0 0.0015 18.4 0.0 1.2 1 0 0 1 1 1 1 Bacterial antitoxin of type II TA system, VapB RHH_8 PF17723.1 AAL63550.1 - 0.0049 17.0 0.0 0.005 17.0 0.0 1.1 1 0 0 1 1 1 1 Ribbon-Helix-Helix transcriptional regulator family ParD_antitoxin PF03693.14 AAL63550.1 - 0.014 15.8 0.0 0.016 15.6 0.0 1.1 1 0 0 1 1 1 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH EamA PF00892.20 AAL63551.1 - 4.9e-29 101.2 40.6 2.6e-15 56.8 13.2 2.0 2 0 0 2 2 2 2 EamA-like transporter family TMEM234 PF10639.9 AAL63551.1 - 0.00019 21.4 8.2 0.0093 16.0 0.8 3.2 2 2 0 2 2 2 2 Putative transmembrane family 234 ATP1G1_PLM_MAT8 PF02038.16 AAL63551.1 - 0.2 11.1 2.9 1.7 8.1 0.5 2.7 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family MttA_Hcf106 PF02416.16 AAL63552.1 - 5.6e-17 60.8 2.1 1.2e-15 56.6 0.3 2.6 3 0 0 3 3 3 1 mttA/Hcf106 family Hom_end PF05204.14 AAL63552.1 - 0.0012 19.0 0.2 0.0017 18.5 0.2 1.2 1 0 0 1 1 1 1 Homing endonuclease ATG22 PF11700.8 AAL63552.1 - 0.041 12.5 0.0 0.043 12.5 0.0 1.0 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like YqgF PF14639.6 AAL63552.1 - 0.083 12.7 0.2 0.098 12.4 0.2 1.1 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 TatC PF00902.18 AAL63553.1 - 4e-43 147.7 18.0 5e-43 147.3 18.0 1.1 1 0 0 1 1 1 1 Sec-independent protein translocase protein (TatC) DUF1772 PF08592.11 AAL63553.1 - 5.6 7.3 9.8 13 6.1 0.9 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) MFS_1 PF07690.16 AAL63556.1 - 2.5e-34 118.8 49.5 2.5e-34 118.8 49.5 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 AAL63556.1 - 0.00082 17.8 0.1 0.00082 17.8 0.1 2.5 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family PSI_PsaF PF02507.15 AAL63556.1 - 0.31 10.9 2.0 0.32 10.8 0.3 1.8 2 0 0 2 2 2 0 Photosystem I reaction centre subunit III AA_kinase PF00696.28 AAL63557.1 - 9.3e-39 133.4 0.0 1.3e-38 133.0 0.0 1.2 1 0 0 1 1 1 1 Amino acid kinase family NT5C PF06941.12 AAL63557.1 - 0.23 11.3 0.0 0.81 9.5 0.0 1.7 2 0 0 2 2 2 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) tRNA-synt_His PF13393.6 AAL63558.1 - 1.3e-66 225.0 0.0 1.7e-66 224.6 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 AAL63558.1 - 8.8e-12 45.0 0.3 2.2e-11 43.8 0.3 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 AAL63558.1 - 5.9e-07 29.6 0.0 3.9e-06 27.0 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.20 AAL63558.1 - 0.001 18.6 0.0 0.0081 15.7 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.20 AAL63558.1 - 0.53 9.3 1.5 21 4.1 0.4 2.6 2 1 1 3 3 3 0 tRNA synthetases class II (D, K and N) Sacchrp_dh_C PF16653.5 AAL63559.1 - 2.4e-22 80.3 0.0 3.1e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 AAL63559.1 - 2.1e-11 44.2 0.0 4.4e-09 36.7 0.0 2.4 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 AAL63559.1 - 0.00018 21.7 0.0 0.00033 20.9 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain Semialdhyde_dh PF01118.24 AAL63559.1 - 0.0014 19.1 0.0 0.0028 18.1 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain ApbA PF02558.16 AAL63559.1 - 0.058 13.0 0.0 0.097 12.3 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Gp_dh_N PF00044.24 AAL63559.1 - 0.086 13.2 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 AAL63559.1 - 0.095 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glycos_transf_2 PF00535.26 AAL63560.1 - 9.3e-33 113.4 0.0 1.7e-32 112.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 GtrA PF04138.14 AAL63560.1 - 1.1e-17 64.3 9.3 1.7e-17 63.7 9.3 1.3 1 0 0 1 1 1 1 GtrA-like protein Glyco_tranf_2_3 PF13641.6 AAL63560.1 - 2.4e-15 57.1 0.2 3.6e-15 56.5 0.2 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 AAL63560.1 - 0.085 12.3 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase like family 2 ATPase PF06745.13 AAL63561.1 - 4.1e-13 49.2 1.0 1.1e-08 34.7 0.0 2.5 2 1 0 2 2 2 2 KaiC AAA_22 PF13401.6 AAL63561.1 - 3.3e-06 27.4 0.0 6e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 AAL63561.1 - 3.7e-05 23.4 0.1 0.00012 21.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 AAL63561.1 - 4.6e-05 22.8 0.0 0.004 16.4 0.1 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 AAL63561.1 - 0.00021 21.3 0.3 0.0023 17.9 0.3 2.1 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea NACHT PF05729.12 AAL63561.1 - 0.00023 21.1 0.0 0.00051 20.0 0.0 1.7 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 AAL63561.1 - 0.00031 21.2 0.0 0.0007 20.0 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 AAL63561.1 - 0.00037 20.9 0.0 0.00069 20.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 AAL63561.1 - 0.001 19.4 0.0 0.0029 18.0 0.0 1.8 2 0 0 2 2 1 1 RNA helicase IstB_IS21 PF01695.17 AAL63561.1 - 0.0019 17.9 0.0 0.011 15.5 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_30 PF13604.6 AAL63561.1 - 0.0031 17.3 0.0 0.0074 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 AAL63561.1 - 0.005 16.9 0.1 0.0052 16.8 0.1 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain PIF1 PF05970.14 AAL63561.1 - 0.0053 16.0 0.6 0.013 14.6 0.1 1.7 2 0 0 2 2 2 1 PIF1-like helicase MobB PF03205.14 AAL63561.1 - 0.008 16.1 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.22 AAL63561.1 - 0.013 15.1 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 AAL63561.1 - 0.013 15.4 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase NTPase_1 PF03266.15 AAL63561.1 - 0.016 15.1 0.1 0.051 13.5 0.1 1.8 2 0 0 2 2 2 0 NTPase PhoH PF02562.16 AAL63561.1 - 0.017 14.6 0.5 0.033 13.7 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein Integrin_alpha PF00357.20 AAL63561.1 - 0.03 14.3 0.6 0.085 12.9 0.6 1.8 1 0 0 1 1 1 0 Integrin alpha cytoplasmic region AAA_18 PF13238.6 AAL63561.1 - 0.034 14.7 0.0 0.061 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 AAL63561.1 - 0.037 13.5 0.0 0.071 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_19 PF13245.6 AAL63561.1 - 0.045 14.1 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 AAL63561.1 - 0.056 12.4 0.1 0.096 11.7 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 AAL63561.1 - 0.057 13.7 0.0 0.16 12.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AAL63561.1 - 0.076 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 AAL63561.1 - 0.1 11.8 0.1 0.15 11.2 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_5 PF07728.14 AAL63561.1 - 0.13 12.2 0.0 0.48 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) TPP_enzyme_C PF02775.21 AAL63562.1 - 2.3e-36 124.9 0.4 3.9e-36 124.2 0.4 1.4 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PFO_beta_C PF12367.8 AAL63562.1 - 5.2e-26 90.6 0.2 1.1e-25 89.6 0.2 1.5 1 0 0 1 1 1 1 Pyruvate ferredoxin oxidoreductase beta subunit C terminal POR_N PF01855.19 AAL63563.1 - 6.1e-58 196.3 0.1 9.4e-58 195.7 0.1 1.2 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.18 AAL63563.1 - 6.8e-30 104.4 2.2 2.1e-15 57.2 0.1 2.6 1 1 1 2 2 2 2 Pyruvate ferredoxin/flavodoxin oxidoreductase TPP_enzyme_N PF02776.18 AAL63563.1 - 3.9e-05 23.3 0.3 9.1e-05 22.1 0.3 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain NDK PF00334.19 AAL63565.1 - 1.4e-45 154.7 0.0 1.9e-26 92.7 0.0 2.1 2 0 0 2 2 2 2 Nucleoside diphosphate kinase DsrH PF04077.12 AAL63565.1 - 0.079 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 DsrH like protein DUF2156 PF09924.9 AAL63565.1 - 0.088 11.8 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2156) PaRep2a PF07903.11 AAL63567.1 - 2.7e-55 185.4 1.3 3e-55 185.3 1.3 1.0 1 0 0 1 1 1 1 PaRep2a protein Glutaredoxin PF00462.24 AAL63567.1 - 0.07 13.4 0.0 0.1 12.9 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin PaRep2b PF07775.11 AAL63568.1 - 6.4e-144 480.2 26.8 3.3e-97 326.1 4.7 3.1 2 2 2 4 4 4 2 PaRep2b protein SesA PF17107.5 AAL63568.1 - 0.0038 17.4 0.5 0.022 15.0 0.5 2.3 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases SDH_sah PF01972.16 AAL63568.1 - 0.021 13.8 0.8 0.23 10.4 0.0 2.5 2 0 0 2 2 2 0 Serine dehydrogenase proteinase Syntaxin-18_N PF10496.9 AAL63568.1 - 0.021 15.0 0.2 0.061 13.6 0.2 1.7 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus UPF0728 PF15092.6 AAL63568.1 - 0.056 13.3 0.3 4 7.3 0.1 3.0 2 1 1 3 3 3 0 Uncharacterised protein family UPF0728 CBFD_NFYB_HMF PF00808.23 AAL63568.1 - 0.11 12.8 0.3 2.1 8.7 0.1 3.3 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF5344 PF17279.2 AAL63568.1 - 0.14 12.7 0.5 0.46 11.1 0.5 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5344) Phasin_2 PF09361.10 AAL63568.1 - 2 8.7 5.5 6.9 7.0 0.6 3.2 2 0 0 2 2 2 0 Phasin protein DUF5446 PF17522.2 AAL63568.1 - 3.5 7.8 5.1 0.67 10.2 0.5 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5446) Proton_antipo_M PF00361.20 AAL63569.1 - 8.6e-18 64.6 20.9 8.6e-18 64.6 20.9 3.0 1 1 1 2 2 2 2 Proton-conducting membrane transporter Proton_antipo_M PF00361.20 AAL63570.1 - 7.1e-48 163.3 25.0 2.3e-45 155.1 22.9 2.7 2 0 0 2 2 2 2 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 AAL63570.1 - 5.3e-07 29.6 1.3 4.2e-06 26.7 0.8 2.9 2 0 0 2 2 2 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus PaRep2a PF07903.11 AAL63572.1 - 1.1e-62 209.3 1.8 1.3e-62 209.0 0.3 1.8 2 0 0 2 2 2 1 PaRep2a protein PaRep2a PF07903.11 AAL63573.1 - 2.4e-60 201.7 0.3 2.7e-60 201.6 0.3 1.0 1 0 0 1 1 1 1 PaRep2a protein PaRep2b PF07775.11 AAL63574.1 - 3.7e-127 424.9 12.3 2.9e-90 303.2 2.1 2.0 1 1 1 2 2 2 2 PaRep2b protein DUF3016 PF11454.8 AAL63574.1 - 0.015 15.0 0.0 0.046 13.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3016) PmbA_TldD PF01523.16 AAL63574.1 - 0.12 12.2 0.4 0.17 11.7 0.4 1.2 1 0 0 1 1 1 0 Putative modulator of DNA gyrase HGD-D PF06050.13 AAL63574.1 - 0.14 11.9 0.1 0.24 11.1 0.1 1.3 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component Proton_antipo_M PF00361.20 AAL63575.1 - 4.3e-48 164.0 26.5 8.9e-48 163.0 26.5 1.5 1 0 0 1 1 1 1 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 AAL63575.1 - 0.00029 20.8 0.9 0.0017 18.4 0.1 2.8 2 0 0 2 2 2 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus DUF2530 PF10745.9 AAL63575.1 - 8.6 6.7 7.9 1.2 9.4 0.7 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF2530) Oxidored_q2 PF00420.24 AAL63576.1 - 2.7e-12 46.3 7.4 3.4e-12 45.9 7.4 1.2 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L BCLP PF12304.8 AAL63576.1 - 0.02 14.5 7.2 0.028 14.0 7.2 1.3 1 1 0 1 1 1 0 Beta-casein like protein DUF3188 PF11384.8 AAL63576.1 - 0.051 13.3 0.4 0.051 13.3 0.4 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3188) Tetraspanin PF00335.20 AAL63576.1 - 3.3 7.4 5.7 4.6 6.9 5.7 1.1 1 0 0 1 1 1 0 Tetraspanin family DUF4418 PF14387.6 AAL63576.1 - 4.1 7.6 9.3 12 6.1 9.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4418) DUF308 PF03729.13 AAL63576.1 - 9.8 6.6 14.4 6.7 7.1 3.0 2.3 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) Oxidored_q3 PF00499.20 AAL63577.1 - 6.9e-06 25.8 19.5 1.8e-05 24.5 19.5 1.7 1 1 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Peptidase_U4 PF03419.13 AAL63577.1 - 0.41 9.9 16.4 0.46 9.7 16.4 1.0 1 0 0 1 1 1 0 Sporulation factor SpoIIGA DUF4436 PF14494.6 AAL63577.1 - 5.5 6.2 12.4 31 3.7 12.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4436) Fer4 PF00037.27 AAL63578.1 - 9.4e-13 47.4 10.5 1.4e-06 27.8 2.9 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 AAL63578.1 - 3.9e-10 40.2 19.3 6e-08 33.2 9.6 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAL63578.1 - 2.8e-09 37.8 5.0 0.00048 21.0 1.0 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_6 PF12837.7 AAL63578.1 - 5e-09 35.8 12.2 0.00013 21.9 2.3 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 AAL63578.1 - 8.4e-09 35.5 7.2 1.3e-08 34.8 7.2 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 AAL63578.1 - 8.8e-09 35.4 4.4 8.5e-05 22.6 0.2 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAL63578.1 - 2.1e-06 28.2 2.4 0.049 14.2 0.4 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 AAL63578.1 - 5.5e-06 26.7 2.2 0.042 14.3 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAL63578.1 - 2.1e-05 24.5 19.4 0.00036 20.6 11.3 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAL63578.1 - 4.3e-05 23.4 13.8 0.002 18.1 1.9 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 AAL63578.1 - 0.00023 21.4 11.5 0.013 16.0 1.2 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_3 PF12798.7 AAL63578.1 - 0.0015 19.3 13.7 0.1 13.6 3.2 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_15 PF13459.6 AAL63578.1 - 0.0028 18.3 5.4 1.1 10.1 1.5 2.4 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_18 PF13746.6 AAL63578.1 - 0.022 15.0 10.0 0.12 12.6 1.4 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 AAL63578.1 - 0.27 11.8 13.0 1.7 9.2 2.3 2.4 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_20 PF14691.6 AAL63578.1 - 0.51 10.1 7.1 0.59 9.9 0.6 2.2 1 1 2 3 3 3 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_22 PF17179.4 AAL63578.1 - 1.2 10.0 8.2 6.7 7.6 0.4 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain NADHdh PF00146.21 AAL63579.1 - 3e-74 250.0 25.0 3.7e-74 249.7 25.0 1.0 1 0 0 1 1 1 1 NADH dehydrogenase Complex1_49kDa PF00346.19 AAL63580.1 - 2.7e-75 252.9 0.0 6.4e-75 251.7 0.0 1.5 2 0 0 2 2 2 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Glycos_transf_2 PF00535.26 AAL63582.1 - 0.016 15.0 0.1 0.041 13.7 0.1 1.6 2 0 0 2 2 2 0 Glycosyl transferase family 2 NTP_transf_3 PF12804.7 AAL63582.1 - 0.047 14.0 1.1 0.085 13.2 0.1 1.9 2 1 0 2 2 2 0 MobA-like NTP transferase domain Glyco_tranf_2_3 PF13641.6 AAL63582.1 - 0.08 12.8 0.1 0.22 11.4 0.0 1.7 2 0 0 2 2 2 0 Glycosyltransferase like family 2 GTP_cyclohydroI PF01227.22 AAL63584.1 - 3.1e-47 160.3 0.0 3.8e-47 160.0 0.0 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I CobW_C PF07683.14 AAL63584.1 - 0.0074 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain DUF3701 PF12482.8 AAL63584.1 - 0.11 12.5 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Phage integrase protein adh_short_C2 PF13561.6 AAL63585.1 - 1.4e-37 129.5 0.0 2.1e-37 128.9 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAL63585.1 - 1.1e-23 83.8 0.0 5.2e-23 81.5 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAL63585.1 - 7.7e-07 29.2 0.1 6.8e-05 22.9 0.1 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 AAL63585.1 - 1.3e-05 24.8 0.0 6.1e-05 22.6 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family LDcluster4 PF18306.1 AAL63585.1 - 0.0016 18.1 0.0 0.0049 16.5 0.0 1.7 2 0 0 2 2 2 1 SLOG cluster4 family RmlD_sub_bind PF04321.17 AAL63585.1 - 0.0057 15.8 0.0 0.0089 15.2 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain DapB_N PF01113.20 AAL63585.1 - 0.014 15.6 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.6 AAL63585.1 - 0.028 14.3 0.1 0.051 13.5 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H-binding CarboxypepD_reg PF13620.6 AAL63586.1 - 0.00021 21.5 7.2 0.33 11.3 0.1 4.1 4 0 0 4 4 4 2 Carboxypeptidase regulatory-like domain B277 PF17623.2 AAL63586.1 - 0.0065 15.6 1.8 1.3 8.0 1.4 2.3 2 0 0 2 2 2 2 Domain of unknown function DUF4493 PF14900.6 AAL63586.1 - 0.016 15.1 0.1 0.065 13.1 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4493) PEGA PF08308.11 AAL63586.1 - 0.076 12.9 1.3 0.49 10.3 0.0 3.0 3 1 0 3 3 3 0 PEGA domain UBX PF00789.20 AAL63586.1 - 0.18 12.0 0.0 3.1 8.1 0.0 2.7 3 0 0 3 3 3 0 UBX domain MarR_2 PF12802.7 AAL63587.1 - 9.1e-09 35.1 0.2 2.3e-08 33.8 0.4 1.5 2 0 0 2 2 2 1 MarR family HTH_Crp_2 PF13545.6 AAL63587.1 - 7.3e-06 25.9 0.1 1.3e-05 25.1 0.1 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain AsnC_trans_reg PF01037.21 AAL63587.1 - 1.5e-05 24.9 0.1 0.00017 21.5 0.0 2.5 2 1 0 2 2 2 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 AAL63587.1 - 4.3e-05 23.0 0.9 6.7e-05 22.4 0.1 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 AAL63587.1 - 4.4e-05 23.3 0.1 0.0001 22.1 0.0 1.6 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 AAL63587.1 - 0.00014 21.9 0.3 0.00031 20.7 0.3 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain RP-C PF03428.13 AAL63587.1 - 0.0016 18.1 0.1 0.0027 17.4 0.1 1.4 1 0 0 1 1 1 1 Replication protein C N-terminal domain LexA_DNA_bind PF01726.16 AAL63587.1 - 0.015 15.0 3.4 0.056 13.2 2.1 2.3 2 1 0 2 2 2 0 LexA DNA binding domain MarR PF01047.22 AAL63587.1 - 0.016 15.2 0.0 0.038 13.9 0.1 1.6 2 0 0 2 2 2 0 MarR family HTH_11 PF08279.12 AAL63587.1 - 0.018 15.0 0.1 0.018 15.0 0.1 2.1 3 0 0 3 3 3 0 HTH domain HTH_8 PF02954.19 AAL63587.1 - 0.033 14.0 0.3 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family HTH_27 PF13463.6 AAL63587.1 - 0.04 14.4 0.7 0.17 12.4 0.7 2.1 1 1 0 1 1 1 0 Winged helix DNA-binding domain Sigma70_r4_2 PF08281.12 AAL63587.1 - 0.043 13.5 0.1 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_IclR PF09339.10 AAL63587.1 - 0.068 13.0 1.4 0.33 10.8 1.4 2.0 1 1 0 1 1 1 0 IclR helix-turn-helix domain HTH_10 PF04967.12 AAL63587.1 - 0.12 12.2 0.5 2.3 8.1 0.1 2.5 2 0 0 2 2 2 0 HTH DNA binding domain Peptidase_M1 PF01433.20 AAL63589.1 - 1.4e-46 158.8 0.2 2.7e-46 157.9 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain HEAT_2 PF13646.6 AAL63589.1 - 7.3e-35 119.2 16.1 1.4e-13 51.0 0.1 4.0 1 1 4 5 5 5 5 HEAT repeats Peptidase_M1_N PF17900.1 AAL63589.1 - 4e-18 66.3 0.0 9.4e-18 65.1 0.0 1.6 1 1 0 1 1 1 1 Peptidase M1 N-terminal domain HEAT_PBS PF03130.16 AAL63589.1 - 1.6e-15 56.1 7.3 0.0072 16.9 0.2 6.9 6 0 0 6 6 6 3 PBS lyase HEAT-like repeat Vitellogenin_N PF01347.22 AAL63589.1 - 4.1e-06 25.5 0.0 0.0011 17.5 0.0 2.1 2 0 0 2 2 2 2 Lipoprotein amino terminal region HEAT PF02985.22 AAL63589.1 - 1.1e-05 25.3 0.2 9.1 6.8 0.0 5.3 5 0 0 5 5 5 1 HEAT repeat DUF2063 PF09836.9 AAL63589.1 - 0.16 12.2 0.2 0.76 10.0 0.0 2.3 2 0 0 2 2 2 0 Putative DNA-binding domain DUF1048 PF06304.11 AAL63589.1 - 0.33 11.4 1.8 9.5 6.7 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1048) TSC22 PF01166.18 AAL63589.1 - 0.38 11.1 3.0 1.1 9.7 3.0 1.8 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF4200 PF13863.6 AAL63589.1 - 0.57 10.6 8.0 0.38 11.2 5.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Atg14 PF10186.9 AAL63589.1 - 1.5 7.9 2.7 27 3.7 0.0 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 BMFP PF04380.13 AAL63589.1 - 3.4 8.2 6.8 28 5.3 6.8 2.5 1 1 0 1 1 1 0 Membrane fusogenic activity UPRTase PF14681.6 AAL63590.1 - 3.5e-51 173.6 0.0 3.9e-51 173.4 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 AAL63590.1 - 2.5e-08 33.6 2.1 4.2e-08 32.8 2.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Peptidase_A24 PF01478.18 AAL63591.1 - 0.0027 18.1 5.2 0.0027 18.1 5.2 1.8 2 0 0 2 2 2 1 Type IV leader peptidase family Arc_PepC_II PF06847.11 AAL63591.1 - 0.069 13.7 0.7 0.21 12.1 0.7 2.0 1 1 0 1 1 1 0 Archaeal Peptidase A24 C-terminus Type II CD20 PF04103.15 AAL63591.1 - 0.23 11.5 3.2 26 4.8 3.0 2.2 2 0 0 2 2 2 0 CD20-like family PaRep2b PF07775.11 AAL63592.1 - 6.4e-07 28.2 0.8 9.6e-07 27.6 0.8 1.3 1 1 0 1 1 1 1 PaRep2b protein PaRep2b PF07775.11 AAL63593.1 - 2.4e-07 29.7 0.0 2.6e-07 29.5 0.0 1.0 1 0 0 1 1 1 1 PaRep2b protein PaRep2b PF07775.11 AAL63594.1 - 3.2e-12 45.7 0.0 3.2e-12 45.7 0.0 1.0 1 0 0 1 1 1 1 PaRep2b protein PaRep2b PF07775.11 AAL63595.1 - 0.016 13.7 0.0 0.016 13.7 0.0 1.0 1 0 0 1 1 1 0 PaRep2b protein PaRep2b PF07775.11 AAL63596.1 - 0.018 13.5 0.0 0.02 13.4 0.0 1.0 1 0 0 1 1 1 0 PaRep2b protein PaRep2a PF07903.11 AAL63598.1 - 9.9e-32 109.3 0.4 1.2e-31 109.1 0.4 1.0 1 0 0 1 1 1 1 PaRep2a protein AXIN1_TNKS_BD PF16646.5 AAL63598.1 - 0.18 12.8 0.0 0.27 12.2 0.0 1.4 1 0 0 1 1 1 0 Axin-1 tankyrase binding domain bact-PGI_C PF10432.9 AAL63599.1 - 4.7e-18 65.7 0.2 1.2e-17 64.4 0.2 1.7 1 1 0 1 1 1 1 Bacterial phospho-glucose isomerase C-terminal SIS domain SIS PF01380.22 AAL63599.1 - 1.1e-05 25.3 0.2 5.7e-05 23.0 0.2 2.1 1 1 0 1 1 1 1 SIS domain ResIII PF04851.15 AAL63600.1 - 2.6e-17 63.3 0.0 8.3e-17 61.7 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 AAL63600.1 - 5.6e-17 62.1 0.2 1.7e-16 60.6 0.2 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 AAL63600.1 - 8.6e-12 44.8 0.1 1.4e-11 44.1 0.1 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 AAL63600.1 - 2.4e-07 30.7 0.1 3.8e-06 26.8 0.0 2.7 2 1 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.23 AAL63600.1 - 5.4e-05 22.1 0.0 0.00087 18.1 0.0 2.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C_2 PF13307.6 AAL63600.1 - 0.0034 17.6 0.9 0.0086 16.3 0.0 1.9 1 1 1 2 2 2 1 Helicase C-terminal domain AAA_22 PF13401.6 AAL63600.1 - 0.011 16.0 0.0 0.046 14.0 0.0 2.1 1 0 0 1 1 1 0 AAA domain HGTP_anticodon PF03129.20 AAL63600.1 - 0.022 14.9 0.1 1 9.6 0.0 3.3 3 0 0 3 3 3 0 Anticodon binding domain DUF2075 PF09848.9 AAL63600.1 - 0.094 11.9 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Terminase_6 PF03237.15 AAL63600.1 - 0.1 12.2 0.0 0.6 9.7 0.0 2.1 2 0 0 2 2 2 0 Terminase-like family TrmB PF01978.19 AAL63601.1 - 3.7e-07 29.9 0.2 6.4e-07 29.2 0.2 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_5 PF01022.20 AAL63601.1 - 6e-06 26.0 0.3 1.1e-05 25.1 0.3 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family MarR PF01047.22 AAL63601.1 - 8e-05 22.5 0.2 0.00013 21.8 0.2 1.2 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 AAL63601.1 - 9e-05 22.3 0.1 0.00013 21.8 0.1 1.2 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 AAL63601.1 - 0.00015 21.2 0.2 0.00026 20.5 0.2 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding TFIIE_alpha PF02002.17 AAL63601.1 - 0.00076 19.3 0.1 0.0016 18.3 0.1 1.5 1 0 0 1 1 1 1 TFIIE alpha subunit HTH_IclR PF09339.10 AAL63601.1 - 0.00085 19.1 0.7 0.0013 18.5 0.7 1.2 1 0 0 1 1 1 1 IclR helix-turn-helix domain DUF977 PF06163.11 AAL63601.1 - 0.0012 18.7 0.0 0.0026 17.7 0.0 1.5 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF977) HTH_17 PF12728.7 AAL63601.1 - 0.0015 18.7 0.1 0.0032 17.6 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain Replic_Relax PF13814.6 AAL63601.1 - 0.0024 18.0 0.1 0.0034 17.5 0.1 1.2 1 0 0 1 1 1 1 Replication-relaxation Penicillinase_R PF03965.16 AAL63601.1 - 0.012 15.9 0.0 0.018 15.4 0.0 1.2 1 0 0 1 1 1 0 Penicillinase repressor HTH_20 PF12840.7 AAL63601.1 - 0.012 15.6 0.2 0.02 14.9 0.2 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Fe_dep_repress PF01325.19 AAL63601.1 - 0.012 15.8 0.5 0.054 13.7 0.0 2.0 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain HTH_DeoR PF08220.12 AAL63601.1 - 0.018 14.8 0.1 0.029 14.1 0.1 1.3 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_27 PF13463.6 AAL63601.1 - 0.044 14.3 0.1 0.078 13.5 0.1 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_Crp_2 PF13545.6 AAL63601.1 - 0.051 13.6 0.1 0.1 12.6 0.1 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_AsnC-type PF13404.6 AAL63601.1 - 0.063 13.1 0.5 0.12 12.2 0.5 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_39 PF14090.6 AAL63601.1 - 0.087 12.6 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_9 PF08221.11 AAL63601.1 - 0.17 12.0 0.1 0.25 11.5 0.1 1.3 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Rrf2 PF02082.20 AAL63601.1 - 0.18 12.2 0.0 0.29 11.5 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator DDRGK PF09756.9 AAL63603.1 - 0.0041 16.7 0.4 0.0048 16.5 0.4 1.1 1 0 0 1 1 1 1 DDRGK domain LIAS_N PF16881.5 AAL63603.1 - 0.065 13.7 0.3 0.096 13.1 0.3 1.4 1 1 0 1 1 1 0 N-terminal domain of lipoyl synthase of Radical_SAM family APS_kinase PF01583.20 AAL63604.1 - 0.16 11.9 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 Adenylylsulphate kinase tRNA-synt_1 PF00133.22 AAL63605.1 - 9e-165 549.3 0.8 1.2e-164 548.9 0.8 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 AAL63605.1 - 3.9e-28 98.3 1.0 7.4e-28 97.4 1.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 AAL63605.1 - 1.4e-24 86.6 1.3 1.2e-09 37.5 0.3 4.2 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 AAL63605.1 - 5.2e-09 35.9 0.0 1.3e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 AAL63605.1 - 4e-07 29.7 0.0 0.00084 18.8 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 AAL63605.1 - 2.7e-05 23.3 0.0 0.00013 21.0 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (K) HscB_4_cys PF18256.1 AAL63605.1 - 0.81 9.6 5.3 1.5 8.7 0.5 2.4 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif PaRep2a PF07903.11 AAL63606.1 - 4.6e-57 191.1 0.8 5.4e-57 190.9 0.8 1.0 1 0 0 1 1 1 1 PaRep2a protein PaRep2b PF07775.11 AAL63607.1 - 2e-76 257.5 1.8 2.4e-76 257.3 1.8 1.0 1 0 0 1 1 1 1 PaRep2b protein WH2 PF02205.20 AAL63607.1 - 0.092 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 WH2 motif DUF2914 PF11141.8 AAL63607.1 - 0.14 11.9 1.3 2 8.2 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2914) TAFH PF07531.14 AAL63607.1 - 0.23 11.6 0.0 0.42 10.8 0.0 1.4 1 0 0 1 1 1 0 NHR1 homology to TAF PaRep2b PF07775.11 AAL63608.1 - 3.7e-54 184.1 2.6 6.2e-42 143.7 1.7 2.0 1 1 1 2 2 2 2 PaRep2b protein PMT_2 PF13231.6 AAL63609.1 - 7.3e-11 42.5 12.5 7.3e-11 42.5 12.5 2.4 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT PF02366.18 AAL63609.1 - 1.9e-09 37.5 16.6 2.6e-08 33.7 14.5 3.4 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 AAL63609.1 - 0.055 13.1 0.2 0.055 13.1 0.2 2.2 2 0 0 2 2 2 0 C-terminal four TMM region of protein-O-mannosyltransferase Auto_anti-p27 PF06677.12 AAL63610.1 - 2.9e-12 46.5 0.8 4.3e-12 46.0 0.8 1.3 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) TF_Zn_Ribbon PF08271.12 AAL63610.1 - 0.0003 20.2 1.9 0.00055 19.4 1.9 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Zn_ribbon_SprT PF17283.2 AAL63610.1 - 0.0014 18.5 0.6 0.0022 17.9 0.6 1.4 1 0 0 1 1 1 1 SprT-like zinc ribbon domain CpXC PF14353.6 AAL63610.1 - 0.0014 18.6 0.1 0.0017 18.4 0.1 1.1 1 0 0 1 1 1 1 CpXC protein OrfB_Zn_ribbon PF07282.11 AAL63610.1 - 0.0015 18.4 0.7 0.0025 17.7 0.2 1.5 2 0 0 2 2 2 1 Putative transposase DNA-binding domain zinc-ribbons_6 PF07191.12 AAL63610.1 - 0.0047 16.9 0.5 0.0073 16.3 0.5 1.3 1 0 0 1 1 1 1 zinc-ribbons DZR PF12773.7 AAL63610.1 - 0.0054 16.7 0.3 0.0085 16.1 0.3 1.3 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.6 AAL63610.1 - 0.0078 15.6 1.0 0.017 14.5 1.0 1.5 1 1 0 1 1 1 1 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 AAL63610.1 - 0.011 15.7 3.1 0.027 14.4 0.5 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-IS66 PF13005.7 AAL63610.1 - 0.047 14.1 3.5 4.6 7.7 0.3 2.4 1 1 1 2 2 2 0 zinc-finger binding domain of transposase IS66 zinc_ribbon_2 PF13240.6 AAL63610.1 - 0.048 13.4 0.7 2.3 8.0 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-RRPl_C4 PF17026.5 AAL63610.1 - 0.049 13.7 0.1 0.057 13.5 0.1 1.2 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type GFA PF04828.14 AAL63610.1 - 0.049 14.0 0.2 1.3 9.4 0.0 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.6 AAL63610.1 - 0.058 13.3 0.1 1.2 9.2 0.0 2.2 2 0 0 2 2 2 0 Nudix N-terminal zf-RRN7 PF11781.8 AAL63610.1 - 0.075 12.7 0.5 0.12 12.1 0.5 1.3 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Sgf11 PF08209.11 AAL63610.1 - 0.076 12.6 0.9 1.7 8.3 0.1 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-C2HC5 PF06221.13 AAL63610.1 - 0.087 12.8 0.3 0.13 12.2 0.3 1.2 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type DNA_ligase_ZBD PF03119.16 AAL63610.1 - 0.091 12.8 5.6 0.82 9.8 5.6 2.3 1 1 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain DUF1258 PF06869.12 AAL63610.1 - 0.14 11.6 0.1 0.17 11.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) Zn-ribbon_8 PF09723.10 AAL63610.1 - 0.21 11.8 2.0 1.6 8.9 1.3 2.4 1 1 2 3 3 3 0 Zinc ribbon domain APH PF01636.23 AAL63611.1 - 0.056 13.4 0.0 2.5 8.0 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 AAL63611.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 RIO1 family PUA PF01472.20 AAL63612.1 - 2.5e-20 72.2 0.4 5e-20 71.3 0.4 1.5 1 0 0 1 1 1 1 PUA domain DUF1947 PF09183.10 AAL63612.1 - 2.4e-07 30.9 0.8 5.8e-07 29.7 0.8 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1947) UPF0113 PF03657.13 AAL63612.1 - 3.5e-06 27.2 0.1 7e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 UPF0113 PUA domain Pre-PUA PF17832.1 AAL63612.1 - 0.00014 22.5 0.2 0.00027 21.6 0.2 1.5 1 1 0 1 1 1 1 Pre-PUA-like domain PUA_3 PF17785.1 AAL63612.1 - 0.033 14.0 0.7 0.23 11.3 0.1 2.5 2 1 0 2 2 2 0 PUA-like domain HTH_3 PF01381.22 AAL63613.1 - 1.1e-11 44.6 0.5 5.6e-11 42.3 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix HTH_31 PF13560.6 AAL63613.1 - 2e-08 34.4 0.2 4.9e-07 30.0 0.0 3.0 3 1 0 3 3 3 1 Helix-turn-helix domain HTH_19 PF12844.7 AAL63613.1 - 1.1e-05 25.3 1.8 4.4e-05 23.4 1.1 2.1 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_11 PF08279.12 AAL63613.1 - 0.00032 20.6 0.5 0.0089 16.0 0.1 2.8 2 0 0 2 2 2 1 HTH domain HTH_23 PF13384.6 AAL63613.1 - 0.0025 17.5 0.0 0.0066 16.2 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain MqsA_antitoxin PF15731.5 AAL63613.1 - 0.0039 17.3 0.0 0.02 15.0 0.0 2.1 2 0 0 2 2 2 1 Antitoxin component of bacterial toxin-antitoxin system, MqsA HTH_7 PF02796.15 AAL63613.1 - 0.0043 17.1 0.1 0.009 16.1 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_25 PF13413.6 AAL63613.1 - 0.039 13.8 0.1 0.089 12.7 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_22 PF13309.6 AAL63613.1 - 0.055 13.6 0.1 0.15 12.1 0.1 1.7 1 0 0 1 1 1 0 HTH domain HTH_Crp_2 PF13545.6 AAL63613.1 - 0.06 13.3 0.1 2.6 8.1 0.0 2.8 3 0 0 3 3 3 0 Crp-like helix-turn-helix domain TRM PF02005.16 AAL63614.1 - 8.2e-77 258.9 0.0 1.3e-76 258.2 0.0 1.3 1 1 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_31 PF13847.6 AAL63614.1 - 1.6e-05 24.8 0.0 2.5e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 AAL63614.1 - 5.3e-05 23.1 0.0 8.3e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 AAL63614.1 - 0.001 18.7 0.0 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 AAL63614.1 - 0.0012 18.7 0.1 0.0018 18.1 0.1 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 AAL63614.1 - 0.0028 18.3 0.0 0.0053 17.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 AAL63614.1 - 0.0047 16.6 0.0 0.0067 16.1 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 AAA_17 PF13207.6 AAL63615.1 - 3.3e-17 63.2 0.1 5.4e-17 62.5 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AAL63615.1 - 5.7e-14 52.8 0.0 8.6e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AAL63615.1 - 1.1e-05 25.6 0.0 2e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 AAL63615.1 - 3.2e-05 23.7 0.1 0.032 13.9 0.0 2.7 2 1 1 3 3 3 2 Thymidylate kinase ADK PF00406.22 AAL63615.1 - 0.00012 22.2 0.0 0.0002 21.5 0.0 1.4 1 1 0 1 1 1 1 Adenylate kinase ATP_bind_2 PF03668.15 AAL63615.1 - 0.00017 21.0 0.3 0.0034 16.7 0.3 2.0 1 1 0 1 1 1 1 P-loop ATPase protein family AAA_5 PF07728.14 AAL63615.1 - 0.0027 17.7 0.1 0.0084 16.1 0.0 1.7 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) SKI PF01202.22 AAL63615.1 - 0.014 15.5 0.3 0.11 12.6 0.3 2.0 1 1 0 1 1 1 0 Shikimate kinase KTI12 PF08433.10 AAL63615.1 - 0.021 14.3 0.0 0.033 13.6 0.0 1.6 1 1 0 1 1 1 0 Chromatin associated protein KTI12 cobW PF02492.19 AAL63615.1 - 0.023 14.3 0.0 1.5 8.3 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain APS_kinase PF01583.20 AAL63615.1 - 0.026 14.4 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Zeta_toxin PF06414.12 AAL63615.1 - 0.04 13.2 0.0 0.064 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 AAL63615.1 - 0.051 13.9 0.1 0.073 13.3 0.1 1.7 1 1 0 1 1 1 0 AAA domain dNK PF01712.19 AAL63615.1 - 0.063 13.1 0.0 4.9 7.0 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase Viral_helicase1 PF01443.18 AAL63615.1 - 0.067 12.9 0.0 0.084 12.6 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.6 AAL63615.1 - 0.08 13.2 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AAL63615.1 - 0.19 12.3 0.1 0.51 10.8 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_19 PF13245.6 AAL63615.1 - 0.31 11.4 1.9 2.8 8.3 1.9 2.3 1 1 0 1 1 1 0 AAA domain PaRep2b PF07775.11 AAL63616.1 - 2e-06 26.6 0.0 2.1e-06 26.6 0.0 1.0 1 0 0 1 1 1 1 PaRep2b protein RNA_binding PF01877.17 AAL63617.1 - 7.1e-17 61.8 0.0 8.4e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 RNA binding UPF0020 PF01170.18 AAL63618.1 - 4.3e-12 46.1 0.0 1.7e-07 31.1 0.0 2.3 1 1 1 2 2 2 2 Putative RNA methylase family UPF0020 MTS PF05175.14 AAL63618.1 - 8.2e-05 22.2 0.0 0.00011 21.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 AAL63618.1 - 0.0012 19.5 0.1 0.0033 18.0 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Eco57I PF07669.11 AAL63618.1 - 0.0013 19.2 0.0 0.0024 18.4 0.0 1.4 1 0 0 1 1 1 1 Eco57I restriction-modification methylase Methyltransf_25 PF13649.6 AAL63618.1 - 0.0016 19.1 0.0 0.0027 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.18 AAL63618.1 - 0.016 14.9 0.0 2.8 7.6 0.0 2.4 2 1 0 2 2 2 0 DNA methylase MethyltransfD12 PF02086.15 AAL63618.1 - 0.17 11.6 0.0 0.17 11.6 0.0 1.8 2 1 1 3 3 3 0 D12 class N6 adenine-specific DNA methyltransferase DUF373 PF04123.13 AAL63619.1 - 2.9e-74 250.5 9.9 4.2e-74 250.0 9.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF373) DUF4395 PF14340.6 AAL63619.1 - 0.071 13.4 0.5 0.071 13.4 0.5 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4395) MscS_porin PF12795.7 AAL63620.1 - 2.6e-07 30.4 47.5 3.7e-05 23.4 25.3 2.5 2 1 0 2 2 2 2 Mechanosensitive ion channel porin domain Sec34 PF04136.15 AAL63620.1 - 7.6e-06 25.9 26.7 0.019 14.9 3.7 4.1 1 1 3 4 4 4 2 Sec34-like family DUF1664 PF07889.12 AAL63620.1 - 2e-05 24.6 31.3 0.0067 16.5 3.1 4.1 2 2 2 4 4 4 3 Protein of unknown function (DUF1664) EzrA PF06160.12 AAL63620.1 - 0.00015 20.1 42.9 0.00016 20.0 10.1 2.8 2 1 0 2 2 2 1 Septation ring formation regulator, EzrA TPR_MLP1_2 PF07926.12 AAL63620.1 - 0.00031 20.8 50.9 0.0076 16.3 3.9 5.0 2 2 3 5 5 4 3 TPR/MLP1/MLP2-like protein Laminin_II PF06009.12 AAL63620.1 - 0.00037 20.5 32.9 0.00073 19.6 6.2 3.2 2 1 1 3 3 3 2 Laminin Domain II Mod_r PF07200.13 AAL63620.1 - 0.00047 20.3 42.3 0.0035 17.4 14.1 4.2 1 1 2 4 4 4 2 Modifier of rudimentary (Mod(r)) protein DUF948 PF06103.11 AAL63620.1 - 0.0013 19.0 15.7 0.011 16.0 0.7 3.8 2 2 2 4 4 4 2 Bacterial protein of unknown function (DUF948) FPP PF05911.11 AAL63620.1 - 0.0022 16.3 40.1 0.0044 15.3 24.4 2.1 1 1 1 2 2 2 2 Filament-like plant protein, long coiled-coil IFT57 PF10498.9 AAL63620.1 - 0.0035 16.4 35.8 0.009 15.0 14.7 3.1 1 1 3 4 4 4 2 Intra-flagellar transport protein 57 DUF4201 PF13870.6 AAL63620.1 - 0.0061 16.3 50.3 0.43 10.3 21.2 3.9 2 2 1 3 3 3 2 Domain of unknown function (DUF4201) Spc7 PF08317.11 AAL63620.1 - 0.0075 15.2 48.1 0.19 10.6 9.5 2.8 1 1 0 2 2 2 2 Spc7 kinetochore protein DUF3450 PF11932.8 AAL63620.1 - 0.0082 15.5 38.8 0.12 11.6 2.4 4.1 2 2 2 4 4 4 3 Protein of unknown function (DUF3450) TACC_C PF05010.14 AAL63620.1 - 0.011 15.6 42.0 0.23 11.2 7.3 3.0 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal CENP-H PF05837.12 AAL63620.1 - 0.014 15.8 42.0 0.16 12.4 7.6 4.0 2 2 2 4 4 4 0 Centromere protein H (CENP-H) Tup_N PF08581.10 AAL63620.1 - 0.015 15.5 3.3 0.015 15.5 3.3 4.3 2 2 1 4 4 3 0 Tup N-terminal MCPsignal PF00015.21 AAL63620.1 - 0.02 14.7 11.1 0.44 10.3 1.8 2.8 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain YkyA PF10368.9 AAL63620.1 - 0.024 14.3 46.9 0.023 14.4 8.1 3.3 1 1 2 3 3 3 0 Putative cell-wall binding lipoprotein Seryl_tRNA_N PF02403.22 AAL63620.1 - 0.027 14.7 46.7 0.07 13.4 16.8 4.8 2 2 3 5 5 5 0 Seryl-tRNA synthetase N-terminal domain KfrA_N PF11740.8 AAL63620.1 - 0.037 14.7 6.5 0.037 14.7 6.5 4.5 2 2 1 4 4 3 0 Plasmid replication region DNA-binding N-term MtrB PF05440.12 AAL63620.1 - 0.038 14.4 4.7 51 4.4 0.0 4.3 2 2 2 4 4 4 0 Tetrahydromethanopterin S-methyltransferase subunit B SHE3 PF17078.5 AAL63620.1 - 0.039 13.7 32.7 0.18 11.5 6.1 2.7 1 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 CENP-F_leu_zip PF10473.9 AAL63620.1 - 0.04 13.9 51.3 0.86 9.6 12.3 3.6 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 AAL63620.1 - 0.048 14.2 52.0 0.074 13.6 28.8 3.9 1 1 2 3 3 3 0 Apg6 coiled-coil region NPV_P10 PF05531.12 AAL63620.1 - 0.051 14.0 20.9 0.33 11.5 6.8 4.4 2 2 3 5 5 4 0 Nucleopolyhedrovirus P10 protein PI3K_P85_iSH2 PF16454.5 AAL63620.1 - 0.059 13.0 41.0 8.5 5.9 5.0 4.0 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain V_ATPase_I PF01496.19 AAL63620.1 - 0.061 11.2 28.1 0.072 11.0 15.7 2.6 1 1 2 3 3 3 0 V-type ATPase 116kDa subunit family SKA2 PF16740.5 AAL63620.1 - 0.062 13.1 35.5 0.2 11.4 3.3 5.3 1 1 3 5 5 5 0 Spindle and kinetochore-associated protein 2 JmjN PF02375.17 AAL63620.1 - 0.068 13.2 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 jmjN domain Atg14 PF10186.9 AAL63620.1 - 0.13 11.3 49.7 0.043 12.9 10.4 3.1 1 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fez1 PF06818.15 AAL63620.1 - 0.13 12.7 37.7 2.2 8.7 11.3 2.6 1 1 1 2 2 2 0 Fez1 AAA_13 PF13166.6 AAL63620.1 - 0.14 10.8 36.7 15 4.1 35.8 2.3 1 1 0 1 1 1 0 AAA domain Golgin_A5 PF09787.9 AAL63620.1 - 0.19 11.2 42.1 0.8 9.1 24.4 2.3 1 1 0 2 2 2 0 Golgin subfamily A member 5 Laminin_I PF06008.14 AAL63620.1 - 0.22 11.2 40.0 0.21 11.3 8.3 2.1 2 0 0 2 2 2 0 Laminin Domain I RasGAP_C PF03836.15 AAL63620.1 - 0.23 11.6 37.7 0.27 11.4 10.4 4.1 2 2 1 3 3 3 0 RasGAP C-terminus TMPIT PF07851.13 AAL63620.1 - 0.24 10.6 31.7 0.14 11.4 10.2 3.5 1 1 3 4 4 4 0 TMPIT-like protein FlaC_arch PF05377.11 AAL63620.1 - 0.24 11.8 26.8 2.7 8.5 2.3 5.8 2 2 4 6 6 6 0 Flagella accessory protein C (FlaC) LPP PF04728.13 AAL63620.1 - 0.26 11.7 15.0 3.7 8.0 0.2 5.0 3 2 2 5 5 5 0 Lipoprotein leucine-zipper zf-C4H2 PF10146.9 AAL63620.1 - 0.27 11.5 38.5 0.49 10.7 8.8 2.4 1 1 1 2 2 2 0 Zinc finger-containing protein COG2 PF06148.11 AAL63620.1 - 0.28 11.3 31.8 1.6 8.8 3.1 4.7 1 1 3 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 WXG100 PF06013.12 AAL63620.1 - 0.29 11.4 10.5 2.1 8.6 1.8 4.7 2 2 2 4 4 4 0 Proteins of 100 residues with WXG YabA PF06156.13 AAL63620.1 - 0.33 11.6 39.6 1.2 9.8 3.3 4.4 2 2 2 4 4 4 0 Initiation control protein YabA DUF4618 PF15397.6 AAL63620.1 - 0.34 10.3 40.5 0.019 14.4 10.9 4.8 1 1 4 5 5 5 0 Domain of unknown function (DUF4618) Med10 PF09748.9 AAL63620.1 - 0.35 10.8 15.2 0.79 9.7 3.3 4.0 2 2 0 2 2 2 0 Transcription factor subunit Med10 of Mediator complex eIF3_N PF09440.10 AAL63620.1 - 0.37 11.2 27.8 0.95 9.9 2.2 4.9 2 2 3 5 5 5 0 eIF3 subunit 6 N terminal domain DUF4407 PF14362.6 AAL63620.1 - 0.47 9.7 29.7 0.41 10.0 3.6 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) TMF_TATA_bd PF12325.8 AAL63620.1 - 0.55 10.5 44.2 0.13 12.5 3.5 4.6 2 2 3 5 5 5 0 TATA element modulatory factor 1 TATA binding OmpH PF03938.14 AAL63620.1 - 0.56 10.5 45.9 0.43 10.9 7.3 3.5 1 1 2 4 4 4 0 Outer membrane protein (OmpH-like) PI_PP_I PF18363.1 AAL63620.1 - 0.62 10.3 11.6 0.14 12.4 2.3 3.7 1 1 4 5 5 4 0 Phosphoinositide phosphatase insertion domain DUF4239 PF14023.6 AAL63620.1 - 0.88 9.3 15.0 0.019 14.7 2.6 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4239) HOOK PF05622.12 AAL63620.1 - 1 7.4 45.4 0.28 9.3 6.8 2.3 1 1 0 2 2 2 0 HOOK protein DUF773 PF05600.12 AAL63620.1 - 1.3 7.7 36.0 0.44 9.2 3.5 3.2 2 1 1 3 3 3 0 CDK5 regulatory subunit-associated protein 3 THOC7 PF05615.13 AAL63620.1 - 1.3 9.3 49.1 0.31 11.3 5.2 4.8 1 1 3 4 4 3 0 Tho complex subunit 7 DUF745 PF05335.13 AAL63620.1 - 1.6 8.4 28.3 0.024 14.3 1.6 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF745) Filament PF00038.21 AAL63620.1 - 2.1 7.8 51.0 0.12 12.0 12.3 3.0 2 1 0 2 2 2 0 Intermediate filament protein FUSC PF04632.12 AAL63620.1 - 2.2 6.7 14.2 8.4 4.8 10.0 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein family ATG16 PF08614.11 AAL63620.1 - 2.3 8.4 45.6 1.7 8.8 27.1 3.0 2 2 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF724 PF05266.14 AAL63620.1 - 2.3 8.0 42.4 0.035 13.9 15.1 3.3 2 1 2 4 4 4 0 Protein of unknown function (DUF724) GAS PF13851.6 AAL63620.1 - 2.4 7.5 55.6 0.1 11.9 7.3 3.8 2 2 1 3 3 3 0 Growth-arrest specific micro-tubule binding DUF2746 PF10874.8 AAL63620.1 - 2.6 8.5 8.6 3.4 8.1 0.3 3.3 2 2 1 3 3 3 0 Protein of unknown function (DUF2746) APG17 PF04108.12 AAL63620.1 - 2.8 6.9 29.3 1.4e+03 -2.0 29.1 3.1 1 1 0 1 1 1 0 Autophagy protein Apg17 FapA PF03961.13 AAL63620.1 - 3.1 6.3 46.9 0.49 8.9 15.0 3.2 1 1 1 3 3 3 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 AAL63620.1 - 3.3 7.9 35.0 1.3 9.2 10.5 3.4 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family FAP206 PF12018.8 AAL63620.1 - 3.4 7.1 27.2 1.7 8.1 4.9 3.1 1 1 2 3 3 3 0 Domain of unknown function Flagellin_C PF00700.21 AAL63620.1 - 4.7 7.6 14.5 1.8 9.0 0.7 4.1 2 2 2 4 4 4 0 Bacterial flagellin C-terminal helical region DASH_Dam1 PF08653.10 AAL63620.1 - 5.5 6.9 8.3 33 4.4 0.1 4.7 3 1 3 6 6 6 0 DASH complex subunit Dam1 HMMR_C PF15908.5 AAL63620.1 - 5.8 7.2 34.9 0.18 12.0 6.7 3.4 2 1 1 3 3 3 0 Hyaluronan mediated motility receptor C-terminal Prefoldin_2 PF01920.20 AAL63620.1 - 5.9 6.9 51.5 6.4 6.8 3.2 5.9 1 1 3 4 4 4 0 Prefoldin subunit DUF812 PF05667.11 AAL63620.1 - 7.8 5.2 45.2 1.3 7.8 10.4 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF812) DUF2730 PF10805.8 AAL63620.1 - 8.3 6.6 25.8 0.94 9.6 3.1 4.2 2 2 2 4 4 4 0 Protein of unknown function (DUF2730) Exonuc_VII_L PF02601.15 AAL63620.1 - 8.6 5.8 36.7 0.88 9.1 9.2 2.2 1 1 1 2 2 2 0 Exonuclease VII, large subunit HMMR_N PF15905.5 AAL63620.1 - 9.7 5.5 47.4 1.6 8.1 26.5 3.0 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor N-terminal DUF4795 PF16043.5 AAL63620.1 - 9.9 5.7 39.0 13 5.3 7.5 3.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4795) HTH_19 PF12844.7 AAL63621.1 - 3.6e-08 33.3 0.0 6.7e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 AAL63621.1 - 7.8e-07 29.1 0.0 1.6e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 AAL63621.1 - 3e-06 27.5 0.0 5.5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.6 AAL63621.1 - 0.0059 16.3 0.1 0.014 15.1 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 AAL63621.1 - 0.022 14.6 0.0 4.9 7.1 0.0 2.5 2 0 0 2 2 2 0 MarR family Ribosomal_L13e PF01294.18 AAL63622.1 - 1.3e-09 38.2 1.3 5e-09 36.3 1.4 1.9 1 1 0 1 1 1 1 Ribosomal protein L13e Ribosomal_L15e PF00827.17 AAL63622.1 - 4.9e-06 26.4 1.9 7.5e-06 25.8 1.9 1.4 1 0 0 1 1 1 1 Ribosomal L15 30K_MP_core PF17644.1 AAL63625.1 - 0.14 12.1 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Core domain of 30K viral movement proteins TFIIB PF00382.19 AAL63626.1 - 3.1e-33 113.6 3.3 1.1e-17 63.8 0.4 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 AAL63626.1 - 3.5e-17 61.6 0.3 5.6e-17 61.0 0.3 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 AAL63626.1 - 2.4e-09 37.0 0.5 4.7e-05 23.1 0.3 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 AAL63626.1 - 2.9e-07 30.6 0.0 0.0016 18.5 0.0 2.4 2 0 0 2 2 2 2 Cyclin, C-terminal domain HTH_11 PF08279.12 AAL63626.1 - 0.00043 20.2 0.1 1.6 8.7 0.0 3.0 3 0 0 3 3 3 2 HTH domain Desulfoferrod_N PF06397.12 AAL63626.1 - 0.0025 17.4 6.8 0.0065 16.1 6.1 2.0 1 1 1 2 2 2 1 Desulfoferrodoxin, N-terminal domain TFIIB_C_1 PF18542.1 AAL63626.1 - 0.0063 16.5 2.2 0.0063 16.5 2.2 2.2 2 0 0 2 2 2 1 Transcription factor IIB C-terminal module 1 A2L_zn_ribbon PF08792.10 AAL63626.1 - 0.013 15.2 2.3 0.023 14.4 2.3 1.3 1 0 0 1 1 1 0 A2L zinc ribbon domain Zn_Tnp_IS91 PF14319.6 AAL63626.1 - 0.022 14.8 0.0 0.056 13.5 0.0 1.6 1 0 0 1 1 1 0 Transposase zinc-binding domain HTH_AsnC-type PF13404.6 AAL63626.1 - 0.027 14.3 0.0 1.3 9.0 0.0 2.8 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Ribosomal_S27e PF01667.17 AAL63626.1 - 0.043 13.5 0.9 0.077 12.7 0.9 1.3 1 0 0 1 1 1 0 Ribosomal protein S27 HTH_Tnp_ISL3 PF13542.6 AAL63626.1 - 0.044 13.2 0.8 3.2 7.2 0.0 3.4 4 0 0 4 4 4 0 Helix-turn-helix domain of transposase family ISL3 Lar_restr_allev PF14354.6 AAL63626.1 - 0.062 13.7 0.3 0.14 12.6 0.3 1.6 1 0 0 1 1 1 0 Restriction alleviation protein Lar Prim_Zn_Ribbon PF08273.12 AAL63626.1 - 0.073 13.4 0.4 0.16 12.3 0.4 1.5 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase Sigma70_r4 PF04545.16 AAL63626.1 - 0.074 12.6 0.5 3.1 7.4 0.0 3.2 3 0 0 3 3 3 0 Sigma-70, region 4 RB_B PF01857.20 AAL63626.1 - 0.15 12.1 0.1 0.26 11.3 0.1 1.4 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain HTH_36 PF13730.6 AAL63626.1 - 0.19 11.7 0.4 9.7 6.2 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain DNA_pol3_delta2 PF13177.6 AAL63627.1 - 4.6e-15 55.8 0.0 2e-10 40.7 0.1 2.3 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 AAL63627.1 - 7.5e-15 55.5 0.0 1.8e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 AAL63627.1 - 9.5e-10 38.8 0.1 4.4e-09 36.6 0.0 2.1 2 0 0 2 2 2 1 Replication factor C C-terminal domain RuvB_N PF05496.12 AAL63627.1 - 3.4e-09 36.7 0.0 8.8e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 AAL63627.1 - 1.5e-07 31.9 0.0 0.00052 20.4 0.0 2.5 1 1 1 2 2 2 2 AAA ATPase domain AAA_assoc_2 PF16193.5 AAL63627.1 - 2.9e-07 30.7 0.1 8.9e-07 29.2 0.1 1.9 1 0 0 1 1 1 1 AAA C-terminal domain AAA_14 PF13173.6 AAL63627.1 - 7.1e-07 29.3 0.0 5.3e-06 26.5 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.6 AAL63627.1 - 8.5e-07 29.3 0.5 0.067 13.5 0.0 3.0 2 1 1 3 3 3 2 AAA domain AAA_3 PF07726.11 AAL63627.1 - 1e-05 25.4 0.0 1.8e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 AAL63627.1 - 1.6e-05 24.9 0.0 4.4e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain Sigma54_activat PF00158.26 AAL63627.1 - 7.6e-05 22.5 0.0 0.46 10.2 0.0 3.1 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_24 PF13479.6 AAL63627.1 - 9e-05 22.3 0.0 0.00024 20.9 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.6 AAL63627.1 - 9.6e-05 22.9 0.0 0.00063 20.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 AAL63627.1 - 0.00013 22.0 0.1 0.00062 19.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 AAL63627.1 - 0.00017 21.2 0.0 0.00033 20.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 AAL63627.1 - 0.00019 20.9 0.0 0.0028 17.1 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI ResIII PF04851.15 AAL63627.1 - 0.00022 21.2 0.0 0.0041 17.1 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 AAL63627.1 - 0.00032 20.2 0.0 0.32 10.4 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_33 PF13671.6 AAL63627.1 - 0.0012 19.0 0.0 0.0027 17.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AAL63627.1 - 0.0013 18.5 0.1 0.0057 16.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain DNA_pol3_delta PF06144.13 AAL63627.1 - 0.0021 17.9 0.0 0.0036 17.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_11 PF13086.6 AAL63627.1 - 0.0022 17.8 0.0 0.0091 15.8 0.0 1.7 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.22 AAL63627.1 - 0.004 17.5 0.0 0.0092 16.4 0.0 1.6 2 0 0 2 2 1 1 RNA helicase AAA_7 PF12775.7 AAL63627.1 - 0.0048 16.4 0.0 0.0092 15.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 AAL63627.1 - 0.0049 16.6 0.0 0.016 14.9 0.0 1.9 1 1 0 1 1 1 1 IstB-like ATP binding protein DEAD PF00270.29 AAL63627.1 - 0.0062 16.3 0.6 0.15 11.8 0.0 2.5 2 1 0 3 3 3 1 DEAD/DEAH box helicase AAA_19 PF13245.6 AAL63627.1 - 0.01 16.2 0.1 0.15 12.4 0.0 2.3 2 1 1 3 3 2 1 AAA domain TIP49 PF06068.13 AAL63627.1 - 0.01 15.0 0.0 0.021 14.0 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain TniB PF05621.11 AAL63627.1 - 0.011 15.2 0.1 0.32 10.4 0.0 2.3 1 1 0 2 2 2 0 Bacterial TniB protein AAA_28 PF13521.6 AAL63627.1 - 0.022 15.0 0.0 0.055 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 AAL63627.1 - 0.049 12.9 0.1 0.82 8.8 0.1 2.2 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 AAL63627.1 - 0.053 13.3 0.0 0.081 12.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_2 PF07724.14 AAL63627.1 - 0.055 13.6 0.0 0.37 10.9 0.0 2.2 3 0 0 3 3 3 0 AAA domain (Cdc48 subfamily) ABC_tran PF00005.27 AAL63627.1 - 0.16 12.5 0.0 0.49 10.9 0.0 1.8 1 1 0 1 1 1 0 ABC transporter Parvo_NS1 PF01057.17 AAL63627.1 - 0.18 10.8 0.0 0.33 10.0 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 KinB_sensor PF16767.5 AAL63628.1 - 0.065 13.7 1.0 0.083 13.3 0.2 1.6 2 0 0 2 2 2 0 Sensor domain of alginate biosynthesis sensor protein KinB CDC37_C PF08564.10 AAL63628.1 - 0.1 12.7 1.1 0.31 11.2 0.4 2.0 2 0 0 2 2 2 0 Cdc37 C terminal domain PIN PF01850.21 AAL63628.1 - 0.3 11.6 4.5 0.26 11.8 2.0 1.9 1 1 1 2 2 2 0 PIN domain z-alpha PF02295.17 AAL63628.1 - 1 9.5 3.9 5.2 7.2 1.2 2.5 1 1 1 2 2 2 0 Adenosine deaminase z-alpha domain TGS PF02824.21 AAL63629.1 - 1.6e-14 53.7 0.0 3e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1_Xtn PF16897.5 AAL63629.1 - 9.1e-13 48.1 0.5 2.4e-12 46.8 0.1 1.9 3 0 0 3 3 3 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 AAL63629.1 - 5.4e-08 32.9 0.0 1.4e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AAL63629.1 - 0.0021 17.6 0.0 0.0036 16.8 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B YchF-GTPase_C PF06071.13 AAL63629.1 - 0.0032 17.6 0.2 0.11 12.7 0.1 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF933) Flavi_capsid PF01003.19 AAL63629.1 - 0.1 12.4 0.7 0.23 11.2 0.3 1.7 2 0 0 2 2 2 0 Flavivirus capsid protein C AAA_28 PF13521.6 AAL63629.1 - 0.1 12.8 0.1 0.51 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 AAL63629.1 - 0.15 12.5 0.0 0.52 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain ECH_1 PF00378.20 AAL63630.1 - 7e-17 61.6 0.0 9.1e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AAL63630.1 - 0.00033 20.2 0.0 0.00035 20.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Iso_dh PF00180.20 AAL63631.1 - 4.4e-96 322.1 0.0 5.3e-96 321.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Acetyltransf_1 PF00583.25 AAL63632.1 - 4.8e-16 59.0 0.0 5.7e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAL63632.1 - 8.9e-14 51.7 0.0 1.3e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAL63632.1 - 3.2e-13 49.7 0.0 4.1e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AAL63632.1 - 1e-09 38.7 0.0 1.2e-09 38.4 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAL63632.1 - 1.2e-08 34.8 0.0 1.8e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 AAL63632.1 - 1.8e-07 31.3 0.1 4.9e-07 29.9 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 AAL63632.1 - 0.0003 20.3 0.4 0.0029 17.1 0.4 2.0 1 1 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_CG PF14542.6 AAL63632.1 - 0.00039 20.5 0.0 0.00068 19.7 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 AAL63632.1 - 0.045 14.4 0.0 0.06 14.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NMD3 PF04981.13 AAL63633.1 - 2.4e-42 145.1 0.0 2.9e-42 144.8 0.0 1.1 1 0 0 1 1 1 1 NMD3 family zf-ribbon_3 PF13248.6 AAL63633.1 - 0.037 13.4 0.8 5.8 6.5 0.0 2.8 3 0 0 3 3 3 0 zinc-ribbon domain DZR PF12773.7 AAL63633.1 - 0.059 13.4 0.9 1.4 9.0 0.6 2.3 2 0 0 2 2 2 0 Double zinc ribbon PyrI_C PF02748.15 AAL63633.1 - 0.074 13.0 0.3 0.75 9.8 0.3 2.4 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Zn-ribbon_8 PF09723.10 AAL63633.1 - 0.11 12.7 5.0 7.7 6.7 0.0 3.2 3 0 0 3 3 3 0 Zinc ribbon domain zf-RING_7 PF02591.15 AAL63633.1 - 0.13 12.4 3.6 8.7 6.6 0.1 3.4 4 0 0 4 4 4 0 C4-type zinc ribbon domain zf-C2HC5 PF06221.13 AAL63633.1 - 0.2 11.7 2.2 6.2 6.9 0.2 3.0 3 0 0 3 3 3 0 Putative zinc finger motif, C2HC5-type PriA_CRR PF18319.1 AAL63633.1 - 0.35 10.9 1.9 0.54 10.3 0.0 2.3 2 0 0 2 2 2 0 PriA DNA helicase Cys-rich region (CRR) domain zf-C2HC_2 PF13913.6 AAL63633.1 - 0.42 10.6 3.5 1 9.4 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zinc-ribbons_6 PF07191.12 AAL63633.1 - 0.44 10.6 4.1 11 6.0 0.0 2.7 2 1 0 2 2 2 0 zinc-ribbons PaRep2b PF07775.11 AAL63634.1 - 1.6e-278 924.3 18.0 2.1e-278 923.9 18.0 1.2 1 0 0 1 1 1 1 PaRep2b protein SPOR PF05036.13 AAL63634.1 - 0.041 14.3 1.9 4.6 7.7 0.1 3.3 2 1 1 3 3 3 0 Sporulation related domain YscJ_FliF PF01514.17 AAL63634.1 - 0.078 12.6 0.1 0.23 11.1 0.1 1.7 1 1 1 2 2 2 0 Secretory protein of YscJ/FliF family PaRep2a PF07903.11 AAL63636.1 - 2.1e-65 218.1 2.4 2.5e-65 217.8 2.4 1.1 1 0 0 1 1 1 1 PaRep2a protein Glutaredoxin PF00462.24 AAL63636.1 - 0.086 13.1 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin DNA_methylase PF00145.17 AAL63637.1 - 7.9e-60 202.9 0.0 5.9e-43 147.5 0.0 2.1 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase Methyltransf_15 PF09445.10 AAL63637.1 - 0.0034 17.0 0.0 0.006 16.2 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 AAL63637.1 - 0.091 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PaRep2b PF07775.11 AAL63640.1 - 1.2e-06 27.4 0.0 1.2e-06 27.3 0.0 1.0 1 0 0 1 1 1 1 PaRep2b protein PaRep2a PF07903.11 AAL63641.1 - 1.5e-11 44.2 0.2 1.5e-11 44.1 0.2 1.0 1 0 0 1 1 1 1 PaRep2a protein PaRep2a PF07903.11 AAL63642.1 - 2.4e-13 50.0 0.0 2.9e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 PaRep2a protein tRNA_synthFbeta PF17759.1 AAL63643.1 - 1.3e-21 77.1 0.0 2e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain B3_4 PF03483.17 AAL63643.1 - 1.2e-11 44.5 0.0 2.1e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 AAL63643.1 - 3.3e-10 40.1 0.4 1.4e-07 31.7 0.1 2.9 3 0 0 3 3 3 2 tRNA synthetase B5 domain PhetRS_B1 PF18262.1 AAL63643.1 - 0.057 13.7 0.0 1.4 9.2 0.0 2.6 1 1 0 1 1 1 0 Phe-tRNA synthetase beta subunit B1 domain PaRep2b PF07775.11 AAL63645.1 - 2.4e-271 900.6 14.3 2.8e-271 900.4 14.3 1.0 1 0 0 1 1 1 1 PaRep2b protein TrwB_AAD_bind PF10412.9 AAL63645.1 - 0.015 14.2 0.0 0.034 13.1 0.0 1.5 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain TBPIP PF07106.13 AAL63645.1 - 0.13 12.2 0.0 0.74 9.8 0.0 2.3 2 0 0 2 2 2 0 TBPIP/Hop2 winged helix domain PaRep2a PF07903.11 AAL63646.1 - 1.2e-14 54.2 0.0 1.2e-14 54.2 0.0 1.0 1 0 0 1 1 1 1 PaRep2a protein PaRep2a PF07903.11 AAL63647.1 - 1.1e-57 193.1 2.6 2.1e-57 192.2 2.6 1.5 1 0 0 1 1 1 1 PaRep2a protein YacG PF03884.14 AAL63648.1 - 0.00099 18.8 0.4 0.0014 18.3 0.4 1.2 1 0 0 1 1 1 1 DNA gyrase inhibitor YacG Lar_restr_allev PF14354.6 AAL63648.1 - 0.0073 16.7 0.2 0.0097 16.3 0.2 1.3 1 0 0 1 1 1 1 Restriction alleviation protein Lar zf-TFIIB PF13453.6 AAL63648.1 - 0.018 14.3 0.2 0.025 13.9 0.2 1.2 1 0 0 1 1 1 0 Transcription factor zinc-finger TF_Zn_Ribbon PF08271.12 AAL63648.1 - 0.048 13.2 1.0 0.1 12.2 0.9 1.6 1 1 0 1 1 1 0 TFIIB zinc-binding RNA_POL_M_15KD PF02150.16 AAL63648.1 - 0.062 13.2 0.7 0.13 12.1 0.7 1.5 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit DUF4503 PF14951.6 AAL63648.1 - 0.071 11.6 0.1 0.076 11.5 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) Ogr_Delta PF04606.12 AAL63648.1 - 0.074 13.0 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger Prok-RING_4 PF14447.6 AAL63648.1 - 0.099 12.5 0.7 0.3 11.0 0.0 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 YdjO PF14169.6 AAL63648.1 - 0.22 11.3 2.8 0.33 10.7 0.2 2.2 1 1 2 3 3 3 0 Cold-inducible protein YdjO tRNA_edit PF04073.15 AAL63650.1 - 1.4e-21 76.9 0.1 3.4e-21 75.6 0.1 1.6 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain DUF1805 PF08827.11 AAL63650.1 - 0.089 13.1 0.1 0.18 12.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) Archease PF01951.16 AAL63651.1 - 6.8e-42 143.0 0.5 7.6e-42 142.8 0.5 1.0 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) OMPdecase PF00215.24 AAL63652.1 - 3.2e-16 59.6 1.1 4.2e-16 59.2 1.1 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family GTP_EFTU_D4 PF14578.6 AAL63652.1 - 0.0026 17.6 2.8 3.5 7.6 0.0 3.1 2 1 1 3 3 3 2 Elongation factor Tu domain 4 HMGL-like PF00682.19 AAL63652.1 - 0.031 13.8 0.3 0.32 10.5 0.1 2.3 1 1 1 2 2 2 0 HMGL-like AAA_17 PF13207.6 AAL63653.1 - 6.6e-32 110.8 0.1 8.2e-32 110.5 0.1 1.1 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 AAL63653.1 - 4.5e-07 29.7 1.3 0.005 16.6 0.0 3.0 2 1 1 3 3 3 2 Thymidylate kinase AAA_18 PF13238.6 AAL63653.1 - 0.00016 22.3 0.1 0.00038 21.0 0.1 1.7 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 AAL63653.1 - 0.013 15.4 0.2 5.2 6.9 0.1 2.5 2 1 0 2 2 2 0 Deoxynucleoside kinase AAA_33 PF13671.6 AAL63653.1 - 0.025 14.7 0.0 0.08 13.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AAL63653.1 - 0.027 14.7 0.0 0.059 13.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 AAL63653.1 - 0.032 14.5 0.2 0.38 11.1 0.1 2.2 1 1 1 2 2 2 0 AAA domain Zeta_toxin PF06414.12 AAL63653.1 - 0.035 13.4 0.0 0.071 12.4 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.6 AAL63653.1 - 0.035 14.3 0.0 0.085 13.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain Arf PF00025.21 AAL63653.1 - 0.1 12.1 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family Viral_helicase1 PF01443.18 AAL63653.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase cobW PF02492.19 AAL63653.1 - 0.17 11.5 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DJ-1_PfpI PF01965.24 AAL63654.1 - 2.3e-15 56.8 0.1 3.4e-14 53.0 0.1 1.9 1 1 0 1 1 1 1 DJ-1/PfpI family Fe-ADH_2 PF13685.6 AAL63655.1 - 2.3e-57 194.6 0.7 5.5e-57 193.3 0.7 1.6 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 AAL63655.1 - 4.2e-24 85.0 4.5 2e-22 79.5 4.5 2.7 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.20 AAL63655.1 - 1.6e-06 27.5 1.9 6.2e-05 22.3 1.9 2.7 1 1 0 1 1 1 1 3-dehydroquinate synthase PUL PF08324.11 AAL63655.1 - 0.0028 16.9 0.8 0.0039 16.5 0.0 1.6 2 0 0 2 2 2 1 PUL domain malic PF00390.19 AAL63657.1 - 9.8e-24 84.1 0.1 2.7e-17 63.2 0.2 2.5 1 1 1 2 2 2 2 Malic enzyme, N-terminal domain Malic_M PF03949.15 AAL63657.1 - 1.7e-23 83.2 0.4 3e-22 79.1 0.4 2.1 1 1 0 1 1 1 1 Malic enzyme, NAD binding domain Shikimate_DH PF01488.20 AAL63657.1 - 0.04 14.0 1.2 6 6.9 0.0 3.0 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Citrate_synt PF00285.21 AAL63658.1 - 2.8e-127 424.7 0.0 3.2e-127 424.5 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain TIP49 PF06068.13 AAL63660.1 - 1.3e-133 445.6 0.5 1.8e-133 445.1 0.5 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 AAL63660.1 - 4.7e-20 71.5 0.9 1.1e-19 70.3 0.3 2.1 2 0 0 2 2 1 1 TIP49 AAA-lid domain AAA PF00004.29 AAL63660.1 - 2.7e-11 44.0 2.2 1.8e-07 31.7 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 AAL63660.1 - 2e-09 37.4 0.9 8.1e-07 28.9 0.0 2.8 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 AAL63660.1 - 2.4e-07 31.3 0.2 1.7e-06 28.5 0.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AAL63660.1 - 4.9e-07 30.1 0.5 0.031 14.5 0.0 3.1 3 0 0 3 3 3 2 AAA domain DnaB_C PF03796.15 AAL63660.1 - 4.5e-05 22.9 0.0 0.00014 21.3 0.0 1.8 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_25 PF13481.6 AAL63660.1 - 0.0013 18.4 0.0 0.0024 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 AAL63660.1 - 0.0014 18.6 0.8 0.0047 16.9 0.1 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 AAL63660.1 - 0.0028 17.4 0.1 0.1 12.3 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_33 PF13671.6 AAL63660.1 - 0.0056 16.8 0.0 0.015 15.5 0.0 1.8 2 0 0 2 2 1 1 AAA domain MazE_antitoxin PF04014.18 AAL63660.1 - 0.008 16.1 0.4 0.035 14.0 0.4 2.1 1 0 0 1 1 1 1 Antidote-toxin recognition MazE, bacterial antitoxin IstB_IS21 PF01695.17 AAL63660.1 - 0.0085 15.8 0.1 0.021 14.5 0.1 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 AAL63660.1 - 0.011 15.2 0.1 0.028 13.9 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 AAL63660.1 - 0.011 15.1 0.3 0.034 13.5 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 AAL63660.1 - 0.012 15.9 0.1 0.06 13.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 AAL63660.1 - 0.013 16.0 0.0 0.031 14.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 AAL63660.1 - 0.016 15.1 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_11 PF13086.6 AAL63660.1 - 0.02 14.7 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 AAL63660.1 - 0.044 14.1 0.3 0.26 11.6 0.1 2.2 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 AAL63660.1 - 0.058 12.8 0.1 0.12 11.8 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.22 AAL63660.1 - 0.066 13.6 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.12 AAL63660.1 - 0.072 12.4 0.1 0.16 11.2 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin ResIII PF04851.15 AAL63660.1 - 0.08 12.9 0.1 0.59 10.1 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF2075 PF09848.9 AAL63660.1 - 0.1 11.8 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 AAL63660.1 - 0.11 12.2 0.2 0.45 10.2 0.1 2.0 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 AAL63660.1 - 0.13 12.2 0.1 0.31 11.0 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 AAL63660.1 - 0.16 12.4 1.4 0.42 11.0 0.0 2.5 3 0 0 3 3 1 0 AAA domain AAA_30 PF13604.6 AAL63660.1 - 0.63 9.7 2.8 1.1 9.0 1.0 2.3 2 1 0 2 2 2 0 AAA domain DUF4064 PF13273.6 AAL63661.1 - 0.16 12.3 8.9 0.73 10.1 8.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) LptF_LptG PF03739.14 AAL63661.1 - 1.6 7.5 12.6 0.049 12.5 5.9 1.7 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG ATP_synt_H PF05493.13 AAL63661.1 - 2.7 8.5 8.7 1.8 9.1 3.8 2.3 2 0 0 2 2 2 0 ATP synthase subunit H DUF4131 PF13567.6 AAL63661.1 - 9.3 5.9 8.7 3.1 7.4 5.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) PaRep2b PF07775.11 AAL63662.1 - 2.6e-113 379.3 9.3 5.4e-74 249.5 1.0 2.0 1 1 1 2 2 2 2 PaRep2b protein SPOR PF05036.13 AAL63662.1 - 0.019 15.4 0.6 12 6.4 0.0 3.2 2 1 0 2 2 2 0 Sporulation related domain PaRep2b PF07775.11 AAL63663.1 - 0.00017 20.2 0.2 0.0002 20.0 0.2 1.0 1 0 0 1 1 1 1 PaRep2b protein DUF4564 PF15169.6 AAL63663.1 - 0.045 13.5 0.2 0.053 13.2 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4564) PaRep2a PF07903.11 AAL63664.1 - 5.3e-35 119.9 3.9 6.3e-35 119.7 3.9 1.0 1 0 0 1 1 1 1 PaRep2a protein Peptidase_M50 PF02163.22 AAL63665.1 - 1.8e-19 70.0 4.1 4.1e-19 68.8 4.1 1.6 1 1 0 1 1 1 1 Peptidase family M50 PDZ_2 PF13180.6 AAL63665.1 - 0.014 15.7 0.1 0.12 12.7 0.0 2.5 2 1 0 2 2 2 0 PDZ domain DUF747 PF05346.11 AAL63665.1 - 0.082 12.4 1.0 0.21 11.0 0.0 1.9 2 0 0 2 2 2 0 Eukaryotic membrane protein family PaRep2b PF07775.11 AAL63668.1 - 2.5e-268 890.6 6.6 3e-268 890.4 6.6 1.0 1 0 0 1 1 1 1 PaRep2b protein SPOR PF05036.13 AAL63668.1 - 0.023 15.0 2.4 3.6 8.0 0.0 3.7 3 1 1 4 4 4 0 Sporulation related domain SusF_SusE PF16411.5 AAL63668.1 - 0.19 12.2 0.9 13 6.3 0.0 2.5 1 1 0 2 2 2 0 Outer membrane protein SusF_SusE PaRep2a PF07903.11 AAL63669.1 - 1.2e-09 38.0 0.6 1.2e-09 38.0 0.6 1.0 1 0 0 1 1 1 1 PaRep2a protein PaRep2a PF07903.11 AAL63670.1 - 1.1e-27 96.3 0.1 1.1e-27 96.2 0.1 1.0 1 0 0 1 1 1 1 PaRep2a protein DUF2208 PF09973.9 AAL63672.1 - 4e-63 213.1 4.2 4.5e-63 213.0 4.2 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2208) Ribosomal_60s PF00428.19 AAL63673.1 - 8e-18 64.8 18.4 1.1e-17 64.4 18.4 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein EF-hand_14 PF17959.1 AAL63673.1 - 0.0061 16.9 0.0 0.0094 16.3 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain GP57 PF17594.2 AAL63673.1 - 0.014 15.1 0.3 0.022 14.5 0.3 1.3 1 0 0 1 1 1 0 Phage Tail fiber assembly helper gene product 57 DUF5010 PF16402.5 AAL63673.1 - 0.14 11.0 0.2 0.15 10.8 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5010) Ribosomal_L38e PF01781.18 AAL63674.1 - 4.1e-05 23.6 0.2 4.6e-05 23.4 0.2 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Cob_adeno_trans PF01923.18 AAL63675.1 - 9.5e-18 64.9 0.0 1.1e-17 64.6 0.0 1.1 1 0 0 1 1 1 1 Cobalamin adenosyltransferase DUF2108 PF09881.9 AAL63675.1 - 0.19 11.7 0.0 0.4 10.7 0.0 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2108) PEP_mutase PF13714.6 AAL63676.1 - 6.2e-60 202.6 0.8 7.1e-60 202.4 0.8 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 AAL63676.1 - 1.3e-13 50.3 0.3 3e-13 49.1 0.2 1.6 1 1 1 2 2 2 1 Isocitrate lyase family ThiG PF05690.14 AAL63676.1 - 0.11 11.7 3.4 2 7.7 1.4 2.7 2 1 0 3 3 3 0 Thiazole biosynthesis protein ThiG MmgE_PrpD PF03972.14 AAL63677.1 - 6e-134 446.9 0.0 7.1e-134 446.6 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family PKcGMP_CC PF16808.5 AAL63678.1 - 0.036 13.9 1.8 0.047 13.6 1.8 1.1 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase RDD PF06271.12 AAL63680.1 - 0.0066 16.7 4.1 0.0066 16.7 4.1 2.7 2 1 0 2 2 2 1 RDD family Peptidase_U4 PF03419.13 AAL63680.1 - 0.77 9.0 10.7 0.15 11.3 7.6 1.4 1 1 1 2 2 2 0 Sporulation factor SpoIIGA Ssu72 PF04722.13 AAL63682.1 - 0.053 13.1 0.0 0.079 12.5 0.0 1.2 1 0 0 1 1 1 0 Ssu72-like protein Radical_SAM PF04055.21 AAL63683.1 - 0.022 15.2 0.0 0.095 13.1 0.0 1.9 1 1 0 1 1 1 0 Radical SAM superfamily Pyr_redox_2 PF07992.14 AAL63684.1 - 2.2e-31 109.2 0.5 2.8e-31 108.9 0.5 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAL63684.1 - 7.6e-16 58.2 1.4 1.4e-11 44.2 0.1 3.0 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AAL63684.1 - 3e-09 36.5 3.6 3.3e-06 26.4 1.1 3.7 1 1 3 4 4 4 2 FAD binding domain DAO PF01266.24 AAL63684.1 - 1.1e-08 35.1 5.3 2.4e-05 24.1 0.3 3.1 2 1 0 3 3 3 2 FAD dependent oxidoreductase GIDA PF01134.22 AAL63684.1 - 2.1e-07 30.4 3.1 5.8e-05 22.3 0.3 3.1 2 1 1 3 3 3 1 Glucose inhibited division protein A Thi4 PF01946.17 AAL63684.1 - 3.9e-06 26.3 0.1 7.7e-06 25.3 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 AAL63684.1 - 9e-06 26.2 1.3 0.027 15.0 0.4 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AAL63684.1 - 5.2e-05 22.8 0.0 5.2e-05 22.8 0.0 2.1 3 0 0 3 3 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AAL63684.1 - 8.3e-05 22.7 0.0 0.00016 21.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 AAL63684.1 - 0.00035 19.4 0.1 0.02 13.6 0.1 2.3 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 AAL63684.1 - 0.0039 16.5 0.6 0.023 13.9 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 AAL63684.1 - 0.0076 15.3 0.5 0.037 13.1 0.3 2.0 1 1 1 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 AAL63684.1 - 0.014 15.4 2.5 0.61 10.1 0.0 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding K_oxygenase PF13434.6 AAL63684.1 - 0.064 12.4 0.2 7.6 5.6 0.0 2.8 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) RcsD_ABL PF16359.5 AAL63684.1 - 0.17 12.0 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 RcsD-ABL domain Mesothelin PF06060.12 AAL63685.1 - 0.028 12.6 0.0 0.045 11.9 0.0 1.3 1 0 0 1 1 1 0 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) Trypsin PF00089.26 AAL63686.1 - 1.2e-07 31.8 0.0 0.014 15.2 0.0 2.1 2 0 0 2 2 2 2 Trypsin Sec_GG PF07549.14 AAL63686.1 - 0.017 14.6 0.0 0.036 13.6 0.0 1.6 1 0 0 1 1 1 0 SecD/SecF GG Motif Ribosomal_S19 PF00203.21 AAL63687.1 - 7.4e-32 109.1 0.2 1.1e-31 108.5 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 Myb_DNA-bind_7 PF15963.5 AAL63687.1 - 0.17 11.8 0.3 0.25 11.3 0.3 1.3 1 0 0 1 1 1 0 Myb DNA-binding like Ribosomal_S17 PF00366.20 AAL63688.1 - 5.2e-20 71.3 3.7 8.1e-20 70.7 3.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Peptidase_M11 PF05548.11 AAL63688.1 - 0.096 11.8 0.1 0.13 11.4 0.1 1.1 1 0 0 1 1 1 0 Gametolysin peptidase M11 PaRep2a PF07903.11 AAL63689.1 - 2.6e-23 82.2 0.0 3.1e-23 81.9 0.0 1.0 1 0 0 1 1 1 1 PaRep2a protein PaRep2a PF07903.11 AAL63690.1 - 1.2e-09 38.0 0.6 1.2e-09 38.0 0.6 1.0 1 0 0 1 1 1 1 PaRep2a protein PaRep2b PF07775.11 AAL63691.1 - 4.5e-270 896.4 15.3 5.2e-270 896.2 15.3 1.0 1 0 0 1 1 1 1 PaRep2b protein PEGA PF08308.11 AAL63691.1 - 0.12 12.2 0.4 0.52 10.2 0.2 2.1 2 0 0 2 2 2 0 PEGA domain ERCC4 PF02732.15 AAL63692.1 - 9.2e-16 58.4 0.0 1.4e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 ERCC4 domain HHH_5 PF14520.6 AAL63692.1 - 0.029 15.0 0.0 0.075 13.6 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain OspE PF02471.17 AAL63692.1 - 0.049 13.8 0.0 0.089 13.0 0.0 1.4 1 0 0 1 1 1 0 Borrelia outer surface protein E RE_ApaLI PF09499.10 AAL63692.1 - 0.18 11.5 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 ApaLI-like restriction endonuclease Glyco_hydro_1 PF00232.18 AAL63693.1 - 6.5e-27 94.0 3.2 1.7e-26 92.7 0.1 2.3 1 1 2 3 3 3 1 Glycosyl hydrolase family 1 Cellulase PF00150.18 AAL63693.1 - 1.6e-06 27.8 0.0 6.3e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_35 PF01301.19 AAL63693.1 - 1.6e-05 24.7 0.1 2.9e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 AAL63693.1 - 1.9e-05 24.2 0.3 0.00023 20.7 0.0 2.0 2 0 0 2 2 2 1 Beta-galactosidase Usp PF00582.26 AAL63694.1 - 2.4e-15 57.3 0.0 3.9e-15 56.6 0.0 1.3 1 1 0 1 1 1 1 Universal stress protein family Pilus_CpaD PF09476.10 AAL63694.1 - 0.019 14.7 0.0 0.024 14.4 0.0 1.1 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) TIR PF01582.20 AAL63694.1 - 0.031 14.1 0.1 0.037 13.8 0.1 1.1 1 0 0 1 1 1 0 TIR domain Gp_dh_C PF02800.20 AAL63695.1 - 5.5e-17 61.8 0.0 7.9e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DapB_N PF01113.20 AAL63695.1 - 3.7e-09 36.8 0.2 9.1e-09 35.5 0.1 1.7 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Gp_dh_N PF00044.24 AAL63695.1 - 0.00037 20.8 0.1 0.0013 19.0 0.2 1.9 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 AAL63695.1 - 0.0023 17.3 2.0 0.012 15.0 0.4 2.5 2 1 1 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 AAL63695.1 - 0.0038 18.0 0.0 0.0082 17.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Sacchrp_dh_NADP PF03435.18 AAL63695.1 - 0.087 13.1 0.1 0.26 11.5 0.1 1.9 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 AAL63695.1 - 0.18 12.4 2.9 1.2 9.8 0.4 3.2 3 2 1 4 4 4 0 NADP oxidoreductase coenzyme F420-dependent PGK PF00162.19 AAL63696.1 - 2.7e-92 309.6 0.0 3.2e-92 309.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Transketolase_C PF02780.20 AAL63696.1 - 0.023 14.6 0.0 0.054 13.4 0.0 1.6 1 0 0 1 1 1 0 Transketolase, C-terminal domain DUF2204 PF09970.9 AAL63697.1 - 4.3e-66 222.0 4.9 4.9e-66 221.8 4.9 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF2204) EspA PF03433.13 AAL63697.1 - 0.045 13.6 0.1 0.08 12.8 0.1 1.4 1 0 0 1 1 1 0 EspA-like secreted protein S4 PF01479.25 AAL63697.1 - 0.2 11.4 0.9 0.89 9.3 0.0 2.5 3 0 0 3 3 3 0 S4 domain tRNA-Thr_ED PF08915.11 AAL63698.1 - 9.3e-45 152.1 0.0 1.7e-44 151.2 0.0 1.5 1 0 0 1 1 1 1 Archaea-specific editing domain of threonyl-tRNA synthetase HGTP_anticodon PF03129.20 AAL63698.1 - 2.8e-23 81.9 1.8 6.4e-23 80.7 1.8 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 AAL63698.1 - 7.4e-21 74.9 0.2 2.3e-20 73.3 0.1 1.8 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) AdoMet_dc PF02675.15 AAL63699.1 - 9.1e-36 122.3 0.1 1e-35 122.2 0.1 1.0 1 0 0 1 1 1 1 S-adenosylmethionine decarboxylase SpoVIF PF14069.6 AAL63699.1 - 0.0022 17.7 0.0 0.0037 17.0 0.0 1.3 1 0 0 1 1 1 1 Stage VI sporulation protein F fragilysinNterm PF16376.5 AAL63699.1 - 0.057 13.2 0.0 0.08 12.7 0.0 1.3 1 1 0 1 1 1 0 N-terminal domain of fragilysin MobB PF03205.14 AAL63703.1 - 2.2e-16 60.0 0.4 3.9e-16 59.1 0.4 1.4 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 AAL63703.1 - 0.0014 18.5 0.1 0.0024 17.8 0.1 1.3 1 0 0 1 1 1 1 NTPase AAA_14 PF13173.6 AAL63703.1 - 0.0059 16.6 0.0 0.0081 16.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 AAL63703.1 - 0.0079 15.4 0.2 0.011 15.0 0.2 1.2 1 0 0 1 1 1 1 NB-ARC domain MeaB PF03308.16 AAL63703.1 - 0.013 14.5 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 AAL63703.1 - 0.033 14.3 0.1 0.033 14.3 0.1 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATPase PF06745.13 AAL63703.1 - 0.054 12.8 0.0 0.065 12.6 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA_35 PF14516.6 AAL63703.1 - 0.054 12.3 0.0 0.065 12.1 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain ATPase_2 PF01637.18 AAL63703.1 - 0.061 13.2 0.0 0.068 13.1 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea APS_kinase PF01583.20 AAL63703.1 - 0.067 13.1 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase PadR PF03551.14 AAL63704.1 - 2.1e-06 27.6 0.0 2.8e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family PaaX PF07848.12 AAL63704.1 - 0.016 15.4 0.2 0.022 15.0 0.2 1.2 1 0 0 1 1 1 0 PaaX-like protein HTH_42 PF06224.12 AAL63704.1 - 0.017 14.7 0.0 0.021 14.4 0.0 1.0 1 0 0 1 1 1 0 Winged helix DNA-binding domain Inos-1-P_synth PF01658.17 AAL63705.1 - 1.6e-22 79.8 0.0 5.6e-22 78.1 0.0 1.8 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase CCG PF02754.16 AAL63706.1 - 1.2e-24 86.3 2.8 4.2e-12 46.1 0.0 3.1 4 0 0 4 4 4 2 Cysteine-rich domain Fer4_8 PF13183.6 AAL63706.1 - 4.3e-08 33.5 4.6 4.3e-08 33.5 4.6 1.8 2 0 0 2 2 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAL63706.1 - 2.6e-05 24.2 13.0 3.8e-05 23.7 10.6 2.4 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAL63706.1 - 3.2e-05 24.0 6.0 3.2e-05 24.0 6.0 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAL63706.1 - 6.2e-05 23.5 4.0 6.2e-05 23.5 4.0 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AAL63706.1 - 0.00071 20.1 10.0 0.002 18.7 8.9 2.4 2 1 1 3 3 3 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAL63706.1 - 0.0021 18.9 5.4 0.0079 17.1 5.4 2.0 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_4 PF12800.7 AAL63706.1 - 0.014 15.9 1.6 0.014 15.9 1.6 2.9 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_2 PF12797.7 AAL63706.1 - 0.014 15.4 11.8 0.12 12.5 2.3 2.9 2 0 0 2 2 2 0 4Fe-4S binding domain CBP_BcsF PF11120.8 AAL63706.1 - 0.035 14.2 0.8 0.1 12.7 0.8 1.8 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsF DUF325 PF03804.13 AAL63706.1 - 0.15 12.1 0.2 0.39 10.8 0.0 1.7 2 0 0 2 2 2 0 Viral proteins of unknown function Fer4_18 PF13746.6 AAL63706.1 - 0.16 12.2 2.0 0.42 10.8 0.1 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain DUF2062 PF09835.9 AAL63706.1 - 0.19 11.6 6.9 0.37 10.7 6.9 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) Cas_Cas4 PF01930.17 AAL63707.1 - 2.9e-16 60.0 0.5 4.7e-16 59.3 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF83 PDDEXK_1 PF12705.7 AAL63707.1 - 2.4e-09 37.5 4.5 0.005 16.8 0.0 3.1 1 1 1 2 2 2 2 PD-(D/E)XK nuclease superfamily PDDEXK_3 PF13366.6 AAL63707.1 - 0.00048 20.5 0.2 0.0012 19.2 0.2 1.7 1 1 1 2 2 2 1 PD-(D/E)XK nuclease superfamily HSDR_N_2 PF13588.6 AAL63707.1 - 0.00078 19.4 0.2 0.0017 18.4 0.2 1.5 1 0 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) Tox-REase-9 PF15650.6 AAL63707.1 - 0.12 12.7 0.1 0.24 11.7 0.1 1.5 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 9 GTP_EFTU PF00009.27 AAL63708.1 - 2.3e-23 82.8 0.0 3.8e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 AAL63708.1 - 1.1e-08 35.3 0.1 7.1e-08 32.7 0.2 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 AAL63708.1 - 0.00033 20.9 0.0 0.00082 19.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain PduV-EutP PF10662.9 AAL63708.1 - 0.0023 17.7 0.5 0.56 9.9 0.2 3.1 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 AAL63708.1 - 0.0067 16.5 0.0 0.019 15.1 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 AAL63708.1 - 0.095 12.9 0.0 8.1 6.7 0.1 2.4 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SKG6 PF08693.10 AAL63708.1 - 1.9 8.0 8.2 0.062 12.7 0.6 2.2 2 0 0 2 2 2 0 Transmembrane alpha-helix domain PaRep2a PF07903.11 AAL63710.1 - 0.15 11.9 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 PaRep2a protein PaRep2a PF07903.11 AAL63712.1 - 3.8e-65 217.2 1.9 4.2e-65 217.1 1.9 1.0 1 0 0 1 1 1 1 PaRep2a protein Glutaredoxin PF00462.24 AAL63712.1 - 0.094 12.9 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin SWC7 PF17330.2 AAL63713.1 - 0.094 12.8 0.1 0.29 11.2 0.1 1.8 1 0 0 1 1 1 0 SWR1 chromatin-remodelling complex, sub-unit Swc7 SMP_C2CD2L PF18696.1 AAL63713.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Synaptotagmin-like, mitochondrial and lipid-binding domain TPR_2 PF07719.17 AAL63713.1 - 2.3 8.5 6.1 20 5.6 0.8 3.9 2 1 1 3 3 3 0 Tetratricopeptide repeat H_PPase PF03030.16 AAL63714.1 - 1.5e-234 780.5 42.8 1.8e-234 780.2 42.8 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase F1F0-ATPsyn_F PF10791.9 AAL63714.1 - 0.18 12.3 0.4 0.62 10.6 0.4 1.9 1 0 0 1 1 1 0 Mitochondrial F1-F0 ATP synthase subunit F of fungi PaRep2a PF07903.11 AAL63715.1 - 3.3e-23 81.8 0.4 3.6e-23 81.7 0.4 1.0 1 0 0 1 1 1 1 PaRep2a protein V_ATPase_I PF01496.19 AAL63716.1 - 7e-21 73.9 14.4 1.5e-16 59.6 0.0 4.1 2 2 3 5 5 5 2 V-type ATPase 116kDa subunit family Prefoldin PF02996.17 AAL63716.1 - 0.076 12.9 8.8 2.7 7.9 0.8 4.0 4 0 0 4 4 4 0 Prefoldin subunit CEP63 PF17045.5 AAL63716.1 - 0.13 12.1 1.7 0.28 11.0 0.1 2.2 2 1 0 2 2 2 0 Centrosomal protein of 63 kDa Lebercilin PF15619.6 AAL63716.1 - 0.36 10.5 8.2 0.37 10.4 0.5 3.0 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease CCDC-167 PF15188.6 AAL63716.1 - 0.99 9.8 3.3 5.6 7.4 0.1 3.3 3 1 1 4 4 4 0 Coiled-coil domain-containing protein 167 Snapin_Pallidin PF14712.6 AAL63716.1 - 1.2 9.5 5.8 7.5 7.0 0.0 4.2 5 1 0 6 6 6 0 Snapin/Pallidin BLOC1_2 PF10046.9 AAL63716.1 - 3 8.2 8.8 27 5.1 0.1 3.9 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spectrin PF00435.21 AAL63716.1 - 4 8.0 5.5 13 6.3 0.1 3.5 3 1 1 4 4 4 0 Spectrin repeat DUF4795 PF16043.5 AAL63716.1 - 4.5 6.8 4.8 12 5.4 0.1 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4795) MTHFR PF02219.17 AAL63717.1 - 2.3e-05 23.9 0.0 3.5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase AAA_31 PF13614.6 AAL63718.1 - 3.2e-20 72.8 0.0 4.2e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 AAL63718.1 - 1e-10 41.8 0.0 1.9e-10 40.9 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 AAL63718.1 - 3.9e-05 23.0 0.4 0.00011 21.5 0.4 1.8 1 1 0 1 1 1 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 AAL63718.1 - 9.8e-05 21.9 0.1 0.0029 17.1 0.1 2.3 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 AAL63718.1 - 0.00041 19.9 0.0 0.00066 19.2 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MipZ PF09140.11 AAL63718.1 - 0.0011 18.3 0.0 0.1 11.9 0.0 2.3 1 1 0 2 2 2 2 ATPase MipZ ParA PF10609.9 AAL63718.1 - 0.0042 16.6 0.2 0.0087 15.5 0.2 1.5 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase VirC1 PF07015.11 AAL63718.1 - 0.032 13.5 0.3 0.058 12.7 0.3 1.4 1 0 0 1 1 1 0 VirC1 protein UPF0086 PF01868.16 AAL63720.1 - 0.00046 20.1 0.0 0.00049 20.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Ribosomal_L29 PF00831.23 AAL63721.1 - 2.3e-16 59.5 5.1 2.3e-16 59.5 5.1 1.4 1 1 0 1 1 1 1 Ribosomal L29 protein DUF2299 PF10061.9 AAL63721.1 - 0.0018 18.0 0.3 0.0019 18.0 0.3 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2299) Spectrin_like PF18373.1 AAL63721.1 - 0.081 13.0 0.9 0.096 12.8 0.2 1.5 2 0 0 2 2 2 0 Spectrin like domain Rad50_zn_hook PF04423.14 AAL63721.1 - 0.09 12.6 0.9 0.09 12.6 0.9 1.9 2 0 0 2 2 2 0 Rad50 zinc hook motif Ribosomal_S3_C PF00189.20 AAL63722.1 - 1.6e-22 79.8 2.2 2.5e-22 79.2 2.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 AAL63722.1 - 2.6e-10 40.0 1.4 4.6e-10 39.2 0.7 1.8 2 0 0 2 2 2 1 KH domain KH_5 PF13184.6 AAL63722.1 - 0.062 13.4 0.3 0.11 12.5 0.3 1.5 1 0 0 1 1 1 0 NusA-like KH domain KH_1 PF00013.29 AAL63722.1 - 0.091 12.6 1.5 0.19 11.6 0.9 2.0 2 0 0 2 2 2 0 KH domain NosD PF05048.13 AAL63723.1 - 5.1e-29 101.2 5.1 6.3e-29 100.9 5.1 1.1 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Beta_helix PF13229.6 AAL63723.1 - 3.4e-13 49.7 12.8 5.3e-13 49.1 12.8 1.2 1 0 0 1 1 1 1 Right handed beta helix region Ribosomal_L22 PF00237.19 AAL63725.1 - 4.2e-25 88.0 0.1 5e-25 87.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF3253 PF11625.8 AAL63725.1 - 0.076 13.3 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3253) TAT_signal PF10518.9 AAL63726.1 - 0.24 11.3 2.0 0.49 10.3 2.0 1.5 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence UbiA PF01040.18 AAL63727.1 - 1.5e-32 112.9 29.7 1.5e-32 112.9 29.7 1.3 1 1 0 1 1 1 1 UbiA prenyltransferase family Hydrolase PF00702.26 AAL63728.1 - 2.1e-08 34.7 0.0 7.4e-08 32.9 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 AAL63728.1 - 2.6e-07 30.9 0.0 2.9e-06 27.5 0.0 2.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 AAL63728.1 - 1.3e-06 28.9 0.1 1.7e-06 28.6 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AAL63728.1 - 0.015 15.3 0.0 0.049 13.7 0.0 1.9 2 0 0 2 2 2 0 HAD-hyrolase-like Hydrolase_3 PF08282.12 AAL63728.1 - 0.034 13.9 0.0 1.8 8.2 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AAL63728.1 - 0.06 13.5 0.1 0.7 10.0 0.0 2.4 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase EF-hand_7 PF13499.6 AAL63729.1 - 0.13 12.8 0.0 0.19 12.2 0.0 1.6 1 1 0 1 1 1 0 EF-hand domain pair TM_helix PF05552.12 AAL63730.1 - 7.9e-11 41.8 15.8 2.8e-07 30.4 4.0 5.0 6 0 0 6 6 6 2 Conserved TM helix ATPase_2 PF01637.18 AAL63731.1 - 1.4e-18 67.7 0.0 7.9e-17 62.0 0.0 2.3 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 AAL63731.1 - 3e-07 30.8 0.0 6.3e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain HTH_IclR PF09339.10 AAL63731.1 - 1.8e-06 27.6 0.0 7.3e-06 25.7 0.0 2.1 1 0 0 1 1 1 1 IclR helix-turn-helix domain AAA_16 PF13191.6 AAL63731.1 - 3.1e-06 27.7 1.6 2.1e-05 24.9 0.8 2.4 2 1 0 2 2 2 1 AAA ATPase domain DUF234 PF03008.14 AAL63731.1 - 3.2e-06 27.5 0.0 9.3e-06 26.0 0.0 1.8 1 1 0 1 1 1 1 Archaea bacterial proteins of unknown function AAA_14 PF13173.6 AAL63731.1 - 9e-06 25.8 0.0 1.9e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain HTH_45 PF14947.6 AAL63731.1 - 0.025 14.6 0.0 0.085 12.9 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn-helix TrmB PF01978.19 AAL63731.1 - 0.035 14.0 0.2 0.26 11.2 0.0 2.4 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB Ribosomal_S6 PF01250.17 AAL63731.1 - 0.052 13.8 0.0 0.3 11.4 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein S6 TniB PF05621.11 AAL63731.1 - 0.19 11.1 0.0 0.53 9.7 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein RVT_3 PF13456.6 AAL63733.1 - 3.8e-16 59.0 0.0 4.8e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase-like RNase_H PF00075.24 AAL63733.1 - 0.0013 18.9 0.0 0.0022 18.2 0.0 1.4 1 1 0 1 1 1 1 RNase H TetR_C_31 PF17940.1 AAL63733.1 - 0.012 15.8 1.1 0.63 10.3 0.4 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain GyrI-like PF06445.15 AAL63734.1 - 1.3e-05 25.5 0.0 2.7e-05 24.5 0.0 1.5 2 0 0 2 2 2 1 GyrI-like small molecule binding domain Cass2 PF14526.6 AAL63734.1 - 0.019 15.1 0.0 0.038 14.1 0.0 1.5 2 0 0 2 2 2 0 Integron-associated effector binding protein NucS PF01939.16 AAL63735.1 - 1.9e-53 181.2 0.0 2.3e-53 180.9 0.0 1.0 1 0 0 1 1 1 1 Endonuclease NucS PDDEXK_4 PF14281.6 AAL63735.1 - 0.0021 18.3 0.0 0.0026 17.9 0.0 1.1 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.17 AAL63735.1 - 0.0075 16.4 0.0 0.016 15.3 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function DUF83 UPF0102 PF02021.17 AAL63735.1 - 0.036 14.3 0.1 0.18 12.1 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0102 Aminotran_3 PF00202.21 AAL63737.1 - 2.4e-119 398.6 0.0 2.9e-119 398.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 AAL63737.1 - 0.046 12.9 0.0 0.082 12.1 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II DciA PF05258.12 AAL63737.1 - 0.12 12.8 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 Dna[CI] antecedent, DciA CelD_N PF02927.14 AAL63738.1 - 0.076 13.9 0.1 0.48 11.3 0.1 2.3 1 1 1 2 2 2 0 Cellulase N-terminal ig-like domain ABC_tran PF00005.27 AAL63744.1 - 2.7e-22 79.7 0.0 4e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAL63744.1 - 3.7e-10 40.1 0.0 4.8e-05 23.3 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAL63744.1 - 4.6e-06 26.2 0.0 0.0026 17.3 0.1 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAL63744.1 - 9.7e-06 25.2 0.1 2.3e-05 24.1 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.6 AAL63744.1 - 1.9e-05 24.8 0.0 3.9e-05 23.8 0.0 1.5 2 0 0 2 2 1 1 AAA domain AAA_23 PF13476.6 AAL63744.1 - 7.6e-05 23.3 0.0 0.00011 22.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AAL63744.1 - 0.0012 18.8 0.1 0.0029 17.5 0.1 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 AAL63744.1 - 0.0089 16.6 0.0 0.18 12.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 AAL63744.1 - 0.016 15.0 0.1 0.028 14.1 0.1 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_16 PF13191.6 AAL63744.1 - 0.016 15.6 0.1 0.043 14.2 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 AAL63744.1 - 0.029 14.3 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_27 PF13514.6 AAL63744.1 - 0.03 13.9 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AAL63744.1 - 0.034 13.7 0.1 0.092 12.3 0.1 1.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 AAL63744.1 - 0.047 14.1 0.0 0.097 13.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 AAL63744.1 - 0.063 13.0 0.1 0.19 11.4 0.1 1.7 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 AAL63744.1 - 0.067 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.6 AAL63744.1 - 0.068 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AAL63744.1 - 0.077 13.3 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 AAL63744.1 - 0.078 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ABC_ATPase PF09818.9 AAL63744.1 - 0.097 11.5 0.1 0.15 10.8 0.1 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class Cytidylate_kin PF02224.18 AAL63744.1 - 0.1 12.3 0.3 0.61 9.8 0.0 2.3 3 1 0 3 3 3 0 Cytidylate kinase MutS_V PF00488.21 AAL63744.1 - 0.11 12.5 0.1 11 5.9 0.1 2.2 2 0 0 2 2 2 0 MutS domain V TsaE PF02367.17 AAL63744.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 AAL63744.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.6 AAL63744.1 - 0.14 12.6 0.0 0.36 11.2 0.0 1.7 2 0 0 2 2 1 0 AAA domain NB-ARC PF00931.22 AAL63744.1 - 0.17 11.0 0.1 0.29 10.3 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain IstB_IS21 PF01695.17 AAL63744.1 - 0.18 11.5 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein cobW PF02492.19 AAL63744.1 - 0.2 11.3 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 AAL63744.1 - 0.2 11.4 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2813 PF11398.8 AAL63744.1 - 0.25 10.5 0.1 0.37 10.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) PaRep2a PF07903.11 AAL63746.1 - 1.1e-09 38.2 0.2 1.2e-09 38.1 0.2 1.0 1 0 0 1 1 1 1 PaRep2a protein PaRep2b PF07775.11 AAL63747.1 - 6.7e-07 28.2 0.0 7.1e-07 28.1 0.0 1.0 1 0 0 1 1 1 1 PaRep2b protein UPF0051 PF01458.17 AAL63748.1 - 1.4e-60 204.7 1.9 4.4e-60 203.1 1.1 1.9 2 0 0 2 2 2 1 Uncharacterized protein family (UPF0051) GIY-YIG PF01541.24 AAL63749.1 - 0.00021 21.5 0.0 0.00029 21.1 0.0 1.2 1 0 0 1 1 1 1 GIY-YIG catalytic domain RHH_3 PF12651.7 AAL63750.1 - 0.061 13.3 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 Ribbon-helix-helix domain DUF2527 PF10736.9 AAL63750.1 - 0.16 11.8 0.1 0.36 10.7 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2627) RimK PF08443.11 AAL63752.1 - 8.6e-30 103.7 0.0 1.1e-29 103.4 0.0 1.1 1 0 0 1 1 1 1 RimK-like ATP-grasp domain GSH-S_ATP PF02955.16 AAL63752.1 - 1.2e-11 44.3 0.0 1.7e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATP-grasp_3 PF02655.14 AAL63752.1 - 3.8e-09 36.8 0.0 9.8e-09 35.5 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.6 AAL63752.1 - 0.01 15.6 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon ATPgrasp_YheCD PF14398.6 AAL63752.1 - 0.011 15.0 0.0 4.1 6.6 0.0 2.2 2 0 0 2 2 2 0 YheC/D like ATP-grasp Ins134_P3_kin PF05770.11 AAL63752.1 - 0.015 14.8 0.1 1.9 7.9 0.1 2.8 3 0 0 3 3 3 0 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain OrfB_Zn_ribbon PF07282.11 AAL63759.1 - 1.4e-09 37.7 0.0 2.9e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Vps16_C PF04840.12 AAL63759.1 - 0.0067 15.5 0.0 0.0095 15.0 0.0 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region LTP_2 PF14368.6 AAL63759.1 - 0.16 12.1 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Probable lipid transfer zf-IS66 PF13005.7 AAL63759.1 - 3.1 8.3 5.4 2.2 8.7 0.9 2.5 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 RNA_binding PF01877.17 AAL63763.1 - 1e-16 61.3 0.0 2.7e-16 59.9 0.0 1.6 1 1 0 1 1 1 1 RNA binding Ribosomal_L15e PF00827.17 AAL63764.1 - 1.4e-55 188.0 4.8 1.7e-55 187.8 4.8 1.0 1 0 0 1 1 1 1 Ribosomal L15 Thy1 PF02511.15 AAL63766.1 - 3.3e-41 141.2 0.7 4e-41 140.9 0.7 1.1 1 0 0 1 1 1 1 Thymidylate synthase complementing protein DUF234 PF03008.14 AAL63766.1 - 0.088 13.3 0.1 0.15 12.6 0.1 1.3 1 0 0 1 1 1 0 Archaea bacterial proteins of unknown function Glycos_transf_2 PF00535.26 AAL63767.1 - 4.8e-19 68.8 0.0 7.3e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAL63767.1 - 8.4e-18 65.1 0.0 1.4e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 AAL63767.1 - 3.2e-13 50.1 23.7 1.6e-12 47.7 17.5 3.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 AAL63767.1 - 7.9e-09 35.2 0.0 2.6e-08 33.5 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 AAL63767.1 - 0.0001 21.9 0.0 0.00025 20.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Osmo_MPGsynth PF09488.10 AAL63767.1 - 0.087 11.5 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) tRNA-synt_2 PF00152.20 AAL63768.1 - 6.4e-76 255.4 0.0 8.9e-76 254.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 AAL63768.1 - 7.3e-09 35.5 0.0 1.5e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 AAL63768.1 - 2.7e-05 23.8 0.0 0.1 12.0 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) LEM PF03020.15 AAL63768.1 - 0.51 9.9 1.4 0.9 9.2 0.0 2.2 2 0 0 2 2 2 0 LEM domain Pyr_redox_2 PF07992.14 AAL63769.1 - 6.1e-05 22.4 0.0 0.00068 19.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 AAL63769.1 - 0.039 14.0 0.1 0.45 10.5 0.0 2.6 4 0 0 4 4 4 0 FAD-NAD(P)-binding UbiD PF01977.16 AAL63771.1 - 8e-132 439.9 0.0 1e-131 439.6 0.0 1.1 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase DUF4129 PF13559.6 AAL63771.1 - 0.094 13.0 4.4 0.15 12.3 0.5 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4129) VIT1 PF01988.19 AAL63772.1 - 1.2e-07 31.8 23.2 1.4e-05 25.1 5.9 2.4 1 1 1 2 2 2 2 VIT family Rubrerythrin PF02915.17 AAL63772.1 - 0.00017 22.0 6.0 0.0014 19.0 6.0 2.1 1 1 0 1 1 1 1 Rubrerythrin SelB-wing_2 PF09106.11 AAL63772.1 - 0.0058 16.8 1.4 0.014 15.6 0.2 2.1 2 0 0 2 2 2 1 Elongation factor SelB, winged helix Peptidase_M26_C PF07580.14 AAL63772.1 - 0.18 10.2 0.2 0.25 9.8 0.2 1.1 1 0 0 1 1 1 0 M26 IgA1-specific Metallo-endopeptidase C-terminal region COQ7 PF03232.13 AAL63772.1 - 0.23 11.2 1.3 1.2 8.9 0.4 2.3 1 1 1 2 2 2 0 Ubiquinone biosynthesis protein COQ7 HTH_24 PF13412.6 AAL63773.1 - 4.4e-07 29.4 0.0 7.8e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 AAL63773.1 - 1.5e-06 28.2 0.0 7.9e-06 25.8 0.0 2.1 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_5 PF01022.20 AAL63773.1 - 1.6e-05 24.7 0.0 3.3e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_23 PF13384.6 AAL63773.1 - 0.0019 18.0 0.0 0.0048 16.7 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain LexA_DNA_bind PF01726.16 AAL63773.1 - 0.0034 17.1 0.0 0.0061 16.3 0.0 1.4 1 0 0 1 1 1 1 LexA DNA binding domain FtsK_gamma PF09397.10 AAL63773.1 - 0.0067 16.2 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Ftsk gamma domain FaeA PF04703.12 AAL63773.1 - 0.0095 16.3 0.0 0.021 15.2 0.0 1.6 1 0 0 1 1 1 1 FaeA-like protein TrmB PF01978.19 AAL63773.1 - 0.0095 15.8 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Sigma70_r4_2 PF08281.12 AAL63773.1 - 0.017 14.8 0.1 0.28 10.9 0.0 2.3 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_11 PF08279.12 AAL63773.1 - 0.02 14.8 0.0 0.054 13.5 0.0 1.8 1 1 0 1 1 1 0 HTH domain HTH_IclR PF09339.10 AAL63773.1 - 0.029 14.1 0.0 0.61 9.9 0.0 2.2 2 0 0 2 2 2 0 IclR helix-turn-helix domain MarR_2 PF12802.7 AAL63773.1 - 0.032 14.1 0.0 0.056 13.3 0.0 1.3 1 0 0 1 1 1 0 MarR family EAP30 PF04157.16 AAL63773.1 - 0.075 12.3 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 EAP30/Vps36 family HTH_28 PF13518.6 AAL63773.1 - 0.075 13.2 0.2 0.14 12.3 0.2 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_41 PF14502.6 AAL63773.1 - 0.084 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_34 PF13601.6 AAL63773.1 - 0.097 12.9 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_38 PF13936.6 AAL63773.1 - 0.14 12.0 0.4 0.44 10.3 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LAGLIDADG_3 PF14528.6 AAL63774.1 - 7.9e-11 42.1 0.0 1.5e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 LAGLIDADG-like domain Staphopain_pro PF14731.6 AAL63774.1 - 0.012 15.6 0.7 5.3 7.0 0.3 2.4 2 0 0 2 2 2 0 Staphopain proregion NucS PF01939.16 AAL63775.1 - 0.014 14.8 0.7 0.03 13.7 0.4 1.6 2 0 0 2 2 2 0 Endonuclease NucS Phage_Mu_Gp45 PF06890.12 AAL63776.1 - 0.11 12.2 0.0 0.32 10.8 0.0 1.7 2 0 0 2 2 2 0 Bacteriophage Mu Gp45 protein Ank_2 PF12796.7 AAL63778.1 - 2.8e-45 152.8 0.2 6.1e-17 62.0 0.1 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 AAL63778.1 - 2.7e-41 139.1 5.2 2.7e-15 56.2 0.1 5.8 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 AAL63778.1 - 2.5e-40 136.3 0.8 1.5e-08 35.0 0.0 6.2 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 AAL63778.1 - 8.3e-35 117.7 12.2 1.3e-07 31.8 0.1 7.3 7 1 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 AAL63778.1 - 1.2e-28 96.0 6.9 9.7e-05 22.5 0.0 8.2 9 1 0 9 9 9 5 Ankyrin repeat GATase_7 PF13537.6 AAL63778.1 - 8.8e-06 25.6 0.1 7.8 6.4 0.0 5.0 5 0 0 5 5 5 1 Glutamine amidotransferase domain EMP70 PF02990.16 AAL63780.1 - 0.0038 16.0 1.6 0.0044 15.8 1.6 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 SUR7 PF06687.12 AAL63780.1 - 0.12 12.0 0.8 0.22 11.1 0.8 1.3 1 0 0 1 1 1 0 SUR7/PalI family Phage_holin_3_6 PF07332.11 AAL63780.1 - 2.5 8.2 20.4 2.1 8.4 1.7 2.2 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III HDOD PF08668.12 AAL63781.1 - 0.077 12.5 0.1 0.1 12.1 0.1 1.1 1 0 0 1 1 1 0 HDOD domain BAG6 PF12057.8 AAL63781.1 - 0.11 12.2 0.7 0.15 11.7 0.7 1.2 1 0 0 1 1 1 0 BCL2-associated athanogene 6 DUF5320 PF17253.2 AAL63781.1 - 0.73 10.9 3.5 2.6 9.2 3.5 1.9 1 1 0 1 1 1 0 Family of unknown function (DUF5320) Tropomyosin PF00261.20 AAL63782.1 - 0.001 18.5 5.1 0.0011 18.4 5.1 1.1 1 0 0 1 1 1 1 Tropomyosin DUF4670 PF15709.5 AAL63782.1 - 0.075 12.4 10.4 0.084 12.2 10.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4670) ARGLU PF15346.6 AAL63782.1 - 0.096 12.6 11.6 0.2 11.5 11.7 1.6 1 1 0 1 1 1 0 Arginine and glutamate-rich 1 Jnk-SapK_ap_N PF09744.9 AAL63782.1 - 0.1 12.8 6.3 0.11 12.7 6.3 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Exonuc_VII_L PF02601.15 AAL63782.1 - 0.19 11.2 1.9 0.21 11.2 1.9 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit U79_P34 PF03064.16 AAL63782.1 - 0.64 9.3 6.3 0.65 9.3 6.3 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF86 PF01934.17 AAL63784.1 - 2.6e-18 66.0 0.2 3.3e-18 65.7 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF86 DUF4145 PF13643.6 AAL63784.1 - 0.058 13.5 0.0 0.1 12.7 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4145) DUF3323 PF11796.8 AAL63784.1 - 0.11 12.3 0.1 0.19 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) Polbeta PF18765.1 AAL63785.1 - 9.1e-05 22.5 0.0 0.00013 22.0 0.0 1.2 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 AAL63785.1 - 0.14 12.4 0.1 0.23 11.8 0.1 1.6 1 1 0 1 1 1 0 Nucleotidyltransferase domain PEP_mutase PF13714.6 AAL63786.1 - 1.7e-40 139.0 0.1 2e-40 138.8 0.1 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 AAL63786.1 - 3.1e-36 125.0 2.4 1.4e-18 66.7 0.2 2.9 2 1 1 3 3 3 2 Isocitrate lyase family ComA PF02679.15 AAL63786.1 - 0.058 12.9 0.1 0.67 9.4 0.1 2.3 2 1 0 2 2 2 0 (2R)-phospho-3-sulfolactate synthase (ComA) Pantoate_transf PF02548.15 AAL63786.1 - 0.084 12.2 0.0 1.2 8.5 0.0 2.1 1 1 1 2 2 2 0 Ketopantoate hydroxymethyltransferase CBS PF00571.28 AAL63787.1 - 4.6e-28 97.4 0.4 3.3e-14 53.1 0.1 2.3 2 1 0 2 2 2 2 CBS domain Dynamitin PF04912.14 AAL63788.1 - 0.11 11.9 0.0 0.17 11.2 0.0 1.3 1 1 0 1 1 1 0 Dynamitin TrmB PF01978.19 AAL63789.1 - 3.7e-05 23.5 0.1 0.0001 22.1 0.1 1.7 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_23 PF13384.6 AAL63789.1 - 0.00016 21.4 1.0 0.0023 17.7 0.0 2.9 2 1 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 AAL63789.1 - 0.0012 18.9 0.3 0.0051 16.9 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_24 PF13412.6 AAL63789.1 - 0.004 16.7 0.1 0.011 15.2 0.0 1.8 1 1 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 AAL63789.1 - 0.0044 16.8 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 AAL63789.1 - 0.0046 16.8 0.1 0.013 15.4 0.1 1.7 1 0 0 1 1 1 1 MarR family GntR PF00392.21 AAL63789.1 - 0.0049 16.5 0.1 0.048 13.3 0.1 2.4 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family RPA_C PF08784.11 AAL63789.1 - 0.0079 16.8 0.0 0.014 16.1 0.0 1.3 1 0 0 1 1 1 1 Replication protein A C terminal HTH_29 PF13551.6 AAL63789.1 - 0.041 13.9 0.0 0.091 12.8 0.0 1.7 1 1 0 1 1 1 0 Winged helix-turn helix HTH_Crp_2 PF13545.6 AAL63789.1 - 0.058 13.4 0.1 0.14 12.2 0.1 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Fe_dep_repress PF01325.19 AAL63789.1 - 0.084 13.1 0.2 0.41 10.9 0.1 2.0 1 1 1 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain Rrf2 PF02082.20 AAL63789.1 - 0.13 12.7 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator Mnd1 PF03962.15 AAL63789.1 - 0.13 12.6 0.1 0.47 10.8 0.0 2.0 2 0 0 2 2 2 0 Mnd1 HTH domain Penicillinase_R PF03965.16 AAL63789.1 - 0.16 12.3 0.1 0.34 11.3 0.1 1.5 1 0 0 1 1 1 0 Penicillinase repressor Phage_terminase PF10668.9 AAL63789.1 - 0.17 11.9 0.0 0.48 10.5 0.0 1.7 2 0 0 2 2 2 0 Phage terminase small subunit ABC_membrane PF00664.23 AAL63790.1 - 0.00054 19.7 0.1 0.0011 18.7 0.1 1.5 1 1 0 1 1 1 1 ABC transporter transmembrane region DUF3800 PF12686.7 AAL63791.1 - 0.00021 21.9 0.0 0.00097 19.8 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3800) PDDEXK_10 PF07788.11 AAL63792.1 - 8.1e-31 105.8 4.0 8.1e-31 105.8 4.0 1.7 2 0 0 2 2 2 1 PD-(D/E)XK nuclease superfamily DUF3782 PF12644.7 AAL63792.1 - 2e-25 88.8 4.0 2.2e-25 88.6 0.7 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3782) ScsC_N PF18312.1 AAL63792.1 - 0.0011 18.8 4.9 0.0049 16.7 0.6 3.4 3 0 0 3 3 3 1 Copper resistance protein ScsC N-terminal domain DUF1664 PF07889.12 AAL63792.1 - 0.011 15.7 0.8 0.79 9.8 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.8 AAL63792.1 - 0.023 14.9 1.7 0.045 14.0 1.7 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding HALZ PF02183.18 AAL63792.1 - 0.028 14.6 0.7 0.3 11.3 0.0 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper PEP-utilisers_N PF05524.13 AAL63792.1 - 0.051 13.7 1.8 0.14 12.3 1.8 1.8 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal NPV_P10 PF05531.12 AAL63792.1 - 0.059 13.8 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF2730 PF10805.8 AAL63792.1 - 0.098 12.8 0.7 0.23 11.6 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Seryl_tRNA_N PF02403.22 AAL63792.1 - 0.14 12.4 2.2 0.26 11.5 2.2 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain PHO4 PF01384.20 AAL63793.1 - 5.3e-23 81.6 33.5 2.7e-12 46.4 3.2 3.1 1 1 2 3 3 3 3 Phosphate transporter family Cu-oxidase_3 PF07732.15 AAL63794.1 - 2.3e-24 85.7 0.8 1.4e-23 83.2 0.2 2.4 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 AAL63794.1 - 2.4e-23 82.4 4.4 2.9e-20 72.4 0.2 3.0 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 AAL63794.1 - 4.7e-07 30.1 0.0 0.00013 22.1 0.0 3.4 3 2 0 3 3 3 1 Multicopper oxidase TAT_signal PF10518.9 AAL63794.1 - 0.0033 17.2 1.2 0.0061 16.4 1.2 1.4 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence Copper-bind PF00127.20 AAL63794.1 - 0.0037 17.7 0.1 3.6 8.1 0.0 2.5 2 0 0 2 2 2 2 Copper binding proteins, plastocyanin/azurin family DUF1192 PF06698.11 AAL63795.1 - 0.022 14.8 1.3 0.052 13.6 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) UBM PF14377.6 AAL63795.1 - 0.16 11.4 1.2 1.6 8.3 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin binding region UPF0175 PF03683.13 AAL63797.1 - 0.0064 16.2 0.1 0.0064 16.2 0.1 1.8 2 1 0 2 2 2 1 Uncharacterised protein family (UPF0175) NTP_transf_2 PF01909.23 AAL63798.1 - 1.3e-08 35.0 0.0 1.8e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 AAL63798.1 - 1.2e-06 28.5 0.0 1.9e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase DUF294 PF03445.13 AAL63798.1 - 0.045 13.6 0.0 0.067 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative nucleotidyltransferase DUF294 HEPN PF05168.14 AAL63799.1 - 2.1e-32 111.7 2.0 2.4e-32 111.5 2.0 1.0 1 0 0 1 1 1 1 HEPN domain SPO22 PF08631.10 AAL63799.1 - 0.0043 16.6 0.1 0.0053 16.3 0.1 1.1 1 0 0 1 1 1 1 Meiosis protein SPO22/ZIP4 like T4SS_CagC PF16943.5 AAL63800.1 - 0.48 10.6 0.0 0.48 10.6 0.0 2.1 2 1 0 2 2 2 0 Cag pathogenicity island, type IV secretory system PaRep2b PF07775.11 AAL63803.1 - 1.4e-72 244.8 3.2 3.9e-53 180.7 0.0 2.1 1 1 1 2 2 2 2 PaRep2b protein SPOR PF05036.13 AAL63803.1 - 0.01 16.2 0.1 0.058 13.8 0.1 2.3 1 0 0 1 1 1 0 Sporulation related domain PaREP1 PF05942.11 AAL63804.1 - 8.1e-26 90.2 8.1 1.1e-25 89.7 8.1 1.2 1 0 0 1 1 1 1 Archaeal PaREP1/PaREP8 family HEPN PF05168.14 AAL63804.1 - 0.00083 19.5 1.6 0.0014 18.8 1.6 1.4 1 0 0 1 1 1 1 HEPN domain DUF5618 PF18498.1 AAL63804.1 - 0.08 13.1 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5618) HEPN PF05168.14 AAL63805.1 - 2e-34 118.3 2.8 2.4e-34 118.0 2.8 1.0 1 0 0 1 1 1 1 HEPN domain NTP_transf_2 PF01909.23 AAL63806.1 - 3.5e-10 40.0 0.0 4.1e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 AAL63806.1 - 1.3e-08 34.8 0.0 1.6e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase Adenyl_cycl_N PF12633.7 AAL63806.1 - 0.17 11.8 0.0 0.2 11.6 0.0 1.1 1 0 0 1 1 1 0 Adenylate cyclase NT domain Adenyl_transf PF04439.12 AAL63806.1 - 0.23 10.5 0.0 0.28 10.3 0.0 1.1 1 0 0 1 1 1 0 Streptomycin adenylyltransferase CPBP PF02517.16 AAL63807.1 - 1.2e-17 64.1 7.3 1.7e-17 63.5 7.3 1.2 1 0 0 1 1 1 1 CPBP intramembrane metalloprotease DUF2516 PF10724.9 AAL63808.1 - 0.0018 18.5 0.1 0.0024 18.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2516) MFS_1 PF07690.16 AAL63810.1 - 2.6e-06 26.6 10.4 3e-06 26.4 10.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 AAL63810.1 - 0.00028 19.9 0.6 0.00048 19.1 0.4 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 AAL63811.1 - 2.9e-10 39.6 14.1 2.9e-10 39.6 14.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.19 AAL63811.1 - 2.5e-05 23.2 5.5 2.8e-05 23.1 5.5 1.2 1 0 0 1 1 1 1 LacY proton/sugar symporter MFS_2 PF13347.6 AAL63811.1 - 0.063 11.8 16.1 0.0074 14.9 7.2 2.2 1 1 1 2 2 2 0 MFS/sugar transport protein Chorismate_synt PF01264.21 AAL63812.1 - 5.3e-119 396.7 0.0 6e-119 396.6 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Shikimate_dh_N PF08501.11 AAL63813.1 - 1.1e-28 99.2 0.1 4.2e-28 97.4 0.1 1.9 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 AAL63813.1 - 8.3e-11 42.1 0.1 1.6e-10 41.2 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase SDH_C PF18317.1 AAL63813.1 - 3.8e-09 36.2 0.1 8.1e-09 35.1 0.1 1.6 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain F420_oxidored PF03807.17 AAL63813.1 - 3.4e-06 27.6 0.9 1.4e-05 25.5 0.6 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 AAL63813.1 - 0.0069 15.7 0.6 0.0069 15.7 0.6 2.0 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain WH2 PF02205.20 AAL63813.1 - 0.046 13.6 0.7 0.084 12.7 0.7 1.4 1 0 0 1 1 1 0 WH2 motif NAD_binding_7 PF13241.6 AAL63813.1 - 0.078 13.4 0.1 0.14 12.7 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF4974 PF16344.5 AAL63815.1 - 0.15 12.1 0.1 0.28 11.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4974) P5CR_dimer PF14748.6 AAL63816.1 - 3.4e-18 65.8 0.0 6.6e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 AAL63816.1 - 3.7e-10 40.2 0.4 1.2e-09 38.6 0.1 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 AAL63816.1 - 6e-06 25.7 0.0 8.7e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 AAL63816.1 - 8.9e-05 22.7 0.0 0.0002 21.6 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Rossmann-like PF10727.9 AAL63816.1 - 0.005 16.7 0.1 0.011 15.6 0.1 1.6 1 0 0 1 1 1 1 Rossmann-like domain ApbA PF02558.16 AAL63816.1 - 0.0067 16.1 0.3 0.014 15.0 0.3 1.6 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 AAL63816.1 - 0.014 15.4 0.1 0.029 14.4 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 AAL63816.1 - 0.017 14.7 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain DapB_N PF01113.20 AAL63816.1 - 0.03 14.5 0.0 0.049 13.8 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.22 AAL63816.1 - 0.089 13.6 0.0 0.21 12.4 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold TrkA_N PF02254.18 AAL63816.1 - 0.13 12.5 0.1 0.26 11.6 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain NUDIX PF00293.28 AAL63817.1 - 6.1e-24 84.5 0.5 6.7e-24 84.4 0.5 1.0 1 0 0 1 1 1 1 NUDIX domain DUF4916 PF16262.5 AAL63817.1 - 0.02 14.4 0.1 0.064 12.8 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4916) dCache_3 PF14827.6 AAL63817.1 - 0.05 13.2 0.0 0.089 12.4 0.0 1.4 1 0 0 1 1 1 0 Double sensory domain of two-component sensor kinase PhoH PF02562.16 AAL63818.1 - 4.2e-52 176.6 0.0 8.5e-52 175.6 0.0 1.5 2 0 0 2 2 2 1 PhoH-like protein KH_2 PF07650.17 AAL63818.1 - 1.5e-13 50.4 0.8 8.7e-12 44.7 0.3 2.5 1 1 1 2 2 2 1 KH domain KH_1 PF00013.29 AAL63818.1 - 3.2e-05 23.7 0.2 0.001 18.9 0.1 2.4 2 0 0 2 2 2 1 KH domain KH_5 PF13184.6 AAL63818.1 - 4.1e-05 23.6 2.1 0.0065 16.5 0.0 2.7 3 0 0 3 3 3 2 NusA-like KH domain AAA_22 PF13401.6 AAL63818.1 - 5.5e-05 23.5 0.0 9.6e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 AAL63818.1 - 0.0003 20.6 0.0 0.00059 19.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_30 PF13604.6 AAL63818.1 - 0.0078 15.9 0.0 0.029 14.1 0.0 2.0 2 1 0 2 2 2 1 AAA domain KH_4 PF13083.6 AAL63818.1 - 0.05 13.5 0.4 6.2 6.8 0.3 2.6 2 0 0 2 2 2 0 KH domain ABC_tran PF00005.27 AAL63818.1 - 0.093 13.2 0.0 0.26 11.8 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AAA_19 PF13245.6 AAL63818.1 - 0.15 12.4 0.0 0.8 10.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain ADH_N PF08240.12 AAL63819.1 - 3.1e-31 107.5 0.2 6.1e-31 106.5 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AAL63819.1 - 2.4e-21 76.1 0.1 3.6e-21 75.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AAL63819.1 - 1.3e-06 29.5 0.0 2.4e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 AAL63819.1 - 0.0098 15.4 0.5 0.014 14.8 0.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 AAL63819.1 - 0.013 14.9 0.1 0.019 14.4 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family KR PF08659.10 AAL63819.1 - 0.043 13.7 0.0 0.065 13.1 0.0 1.2 1 0 0 1 1 1 0 KR domain CMAS PF02353.20 AAL63819.1 - 0.069 12.4 0.0 0.098 11.9 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Epimerase PF01370.21 AAL63820.1 - 1e-54 185.6 0.0 1.2e-54 185.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AAL63820.1 - 1.3e-46 159.6 0.0 2.8e-46 158.5 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 AAL63820.1 - 1.8e-18 66.5 0.0 2.7e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 AAL63820.1 - 9.9e-17 60.9 0.0 1.2e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 AAL63820.1 - 2.9e-16 59.5 0.2 6.4e-15 55.1 0.2 2.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 AAL63820.1 - 2.9e-11 43.0 0.3 2.6e-06 26.8 0.1 2.5 2 1 0 2 2 2 2 Male sterility protein adh_short PF00106.25 AAL63820.1 - 2.5e-06 27.1 0.5 0.00053 19.5 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.6 AAL63820.1 - 3.7e-06 26.9 0.0 7.1e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 AAL63820.1 - 0.0059 16.5 0.1 0.014 15.3 0.0 1.6 2 0 0 2 2 2 1 KR domain NmrA PF05368.13 AAL63820.1 - 0.017 14.7 0.4 0.037 13.6 0.3 1.7 2 1 0 2 2 2 0 NmrA-like family NAD_binding_2 PF03446.15 AAL63820.1 - 0.022 15.0 0.0 0.039 14.1 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.18 AAL63820.1 - 0.024 14.9 0.1 0.051 13.8 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 AAL63820.1 - 0.029 13.9 0.0 0.053 13.1 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 AAL63820.1 - 0.034 14.7 0.0 0.078 13.6 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox PF00070.27 AAL63820.1 - 0.045 14.3 0.2 0.1 13.1 0.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 AAL63820.1 - 0.071 12.3 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PAC2 PF09754.9 AAL63820.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.5 1 1 0 1 1 1 0 PAC2 family EPSP_synthase PF00275.20 AAL63821.1 - 2.4e-61 207.7 0.0 3.1e-61 207.3 0.0 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) B5 PF03484.15 AAL63821.1 - 0.037 14.3 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 tRNA synthetase B5 domain DIM PF08194.12 AAL63821.1 - 1 9.6 3.8 24 5.2 0.0 3.5 3 0 0 3 3 3 0 DIM protein DHQ_synthase PF01761.20 AAL63822.1 - 2.1e-88 295.9 0.0 2.5e-88 295.6 0.0 1.0 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 AAL63822.1 - 1.9e-05 24.5 0.1 0.00011 22.0 0.1 2.0 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 AAL63822.1 - 0.00031 19.7 2.0 0.0044 15.9 2.0 2.4 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Transket_pyr PF02779.24 AAL63823.1 - 5e-33 114.2 0.1 1.6e-32 112.6 0.0 1.7 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 AAL63823.1 - 3.5e-27 94.7 0.0 5.7e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 AAL63823.1 - 0.011 16.0 0.0 0.021 15.2 0.0 1.5 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II HCV_NS4a PF01006.20 AAL63823.1 - 0.74 9.6 2.6 12 5.8 1.3 2.6 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein NS4a Transketolase_N PF00456.21 AAL63824.1 - 5.1e-39 134.1 0.2 1.1e-38 133.0 0.2 1.4 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.6 AAL63824.1 - 5.3e-13 48.8 0.2 1.9e-09 37.2 0.3 2.7 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 AAL63824.1 - 4.3e-08 33.1 1.5 2.2e-06 27.6 0.2 3.0 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 AAL63824.1 - 1.6e-07 30.6 0.0 2.5e-07 29.9 0.0 1.2 1 1 0 1 1 1 1 Dehydrogenase E1 component GTP_EFTU_D4 PF14578.6 AAL63824.1 - 0.039 13.9 0.3 0.1 12.5 0.3 1.7 1 0 0 1 1 1 0 Elongation factor Tu domain 4 tRNA-synt_1b PF00579.25 AAL63825.1 - 1.1e-43 149.7 0.0 1.2e-41 143.0 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) DAHP_synth_1 PF00793.20 AAL63826.1 - 1.2e-68 231.0 0.0 1.5e-68 230.7 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family NeuB PF03102.14 AAL63826.1 - 1.2e-06 28.1 0.0 4.3e-06 26.4 0.0 1.7 1 1 0 1 1 1 1 NeuB family NdhM PF10664.9 AAL63826.1 - 0.09 13.0 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Cyanobacterial and plastid NDH-1 subunit M NTP_transf_3 PF12804.7 AAL63827.1 - 2.1e-30 106.2 0.7 2.7e-30 105.8 0.7 1.0 1 0 0 1 1 1 1 MobA-like NTP transferase domain CTP_transf_3 PF02348.19 AAL63827.1 - 6e-06 26.3 0.0 7.9e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase Hydrolase PF00702.26 AAL63827.1 - 0.19 12.0 0.0 0.26 11.5 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase MTS PF05175.14 AAL63827.1 - 0.21 11.1 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Ald_Xan_dh_C2 PF02738.18 AAL63828.1 - 1.1e-164 549.0 0.4 1.6e-164 548.4 0.4 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 AAL63828.1 - 3.7e-22 78.8 0.2 6.5e-14 52.2 0.0 2.7 1 1 1 2 2 2 2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 AAL63829.1 - 6.1e-22 77.4 0.2 6.1e-22 77.4 0.2 1.8 2 0 0 2 2 2 1 [2Fe-2S] binding domain Fer2 PF00111.27 AAL63829.1 - 2.4e-06 27.4 0.3 2.4e-06 27.4 0.3 2.1 1 1 1 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 AAL63829.1 - 7.7e-05 22.7 0.6 7.7e-05 22.7 0.6 1.8 1 1 1 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain FAD_binding_5 PF00941.21 AAL63830.1 - 6.6e-40 136.6 0.0 1.3e-39 135.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 AAL63830.1 - 1.2e-22 80.0 0.7 2.3e-22 79.1 0.7 1.5 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain PDH PF02153.17 AAL63831.1 - 1e-11 44.4 0.0 1.7e-11 43.6 0.0 1.3 1 1 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 AAL63831.1 - 0.00037 21.0 0.1 0.0088 16.6 0.1 2.4 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.9 AAL63831.1 - 0.24 11.3 0.6 3.3 7.6 0.6 2.3 1 1 0 1 1 1 0 Rossmann-like domain BiPBP_C PF06832.12 AAL63834.1 - 0.12 12.4 0.1 22 5.2 0.0 3.7 4 0 0 4 4 4 0 Penicillin-Binding Protein C-terminus Family HTH_24 PF13412.6 AAL63835.1 - 9.9e-07 28.2 0.0 2.6e-06 26.9 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 AAL63835.1 - 2.2e-05 24.2 0.0 3.8e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 AAL63835.1 - 0.00023 21.2 0.0 0.00042 20.3 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain DUF977 PF06163.11 AAL63835.1 - 0.1 12.5 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) FaeA PF04703.12 AAL63835.1 - 0.2 12.1 0.2 0.2 12.1 0.2 1.7 2 0 0 2 2 2 0 FaeA-like protein DUF86 PF01934.17 AAL63836.1 - 2.3e-11 43.6 0.0 2.6e-11 43.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF86 Polbeta PF18765.1 AAL63837.1 - 1.3e-13 50.8 0.0 1.9e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 AAL63837.1 - 3.3e-07 30.5 0.4 1.1e-05 25.7 0.1 2.1 2 0 0 2 2 2 1 Nucleotidyltransferase domain DUF1576 PF07613.11 AAL63838.1 - 0.0055 16.2 2.8 0.0059 16.1 2.4 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1576) Wzy_C PF04932.15 AAL63838.1 - 2.4 7.8 22.4 2 8.1 6.7 2.0 1 1 1 2 2 2 0 O-Antigen ligase DUF2070 PF09843.9 AAL63838.1 - 2.6 6.2 11.5 2.9 6.1 11.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Peptidase_A24 PF01478.18 AAL63838.1 - 4.5 7.7 12.8 0.24 11.8 2.6 2.3 1 1 1 2 2 2 0 Type IV leader peptidase family Tad PF13400.6 AAL63839.1 - 0.15 12.3 1.1 0.15 12.3 1.1 3.7 3 1 0 3 3 3 0 Putative Flp pilus-assembly TadE/G-like MMR_HSR1 PF01926.23 AAL63842.1 - 4.3e-06 26.8 0.0 5.5e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 AAL63842.1 - 2.2e-05 24.1 0.2 0.00019 21.1 0.2 2.0 1 1 0 1 1 1 1 Ras family RsgA_GTPase PF03193.16 AAL63842.1 - 0.0055 16.6 0.1 0.42 10.5 0.2 2.4 2 1 0 2 2 2 1 RsgA GTPase Arf PF00025.21 AAL63842.1 - 0.0065 15.9 0.0 0.011 15.2 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 AAL63842.1 - 0.017 15.4 0.4 0.14 12.4 0.4 2.0 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 AAL63842.1 - 0.078 12.6 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 AAL63842.1 - 0.18 11.5 0.0 0.18 11.5 0.0 1.2 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 AAL63842.1 - 0.21 11.3 0.0 0.25 11.0 0.0 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DHquinase_I PF01487.15 AAL63843.1 - 1.8e-45 156.0 0.0 2.5e-45 155.5 0.0 1.1 1 0 0 1 1 1 1 Type I 3-dehydroquinase CM_2 PF01817.21 AAL63843.1 - 9.4e-13 48.3 0.1 4.5e-12 46.2 0.0 2.1 2 0 0 2 2 2 1 Chorismate mutase type II GP88 PF17338.2 AAL63844.1 - 3.8e-14 52.7 0.6 6.3e-14 52.0 0.6 1.2 1 0 0 1 1 1 1 Gene product 88 Aminotran_1_2 PF00155.21 AAL63845.1 - 2.1e-32 112.7 0.0 3.3e-32 112.0 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 AAL63845.1 - 0.0006 18.8 0.0 0.00082 18.3 0.0 1.1 1 0 0 1 1 1 1 Allinase DUF4380 PF14315.6 AAL63845.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4380) GHMP_kinases_N PF00288.26 AAL63847.1 - 2.5e-09 37.2 1.1 6.9e-09 35.8 1.1 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 AAL63847.1 - 0.023 15.0 0.2 0.11 12.9 0.0 2.3 2 0 0 2 2 2 0 GHMP kinases C terminal Glyco_hydro_31 PF01055.26 AAL63848.1 - 1.5e-124 416.6 0.0 1.8e-124 416.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 AAL63848.1 - 2.5e-15 56.6 0.2 6.9e-15 55.1 0.2 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like GHL10 PF02638.15 AAL63848.1 - 0.00051 19.2 0.5 0.15 11.1 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase-like 10 GHL15 PF14885.6 AAL63848.1 - 0.085 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 15 GHL6 PF14871.6 AAL63848.1 - 0.15 12.2 0.0 22 5.2 0.0 2.5 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 DUF2175 PF09943.9 AAL63849.1 - 3.6e-35 120.2 0.3 4e-35 120.0 0.3 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2175) XkdW PF09636.10 AAL63849.1 - 0.013 15.6 0.2 0.025 14.7 0.2 1.5 2 0 0 2 2 2 0 XkdW protein YhfH PF14149.6 AAL63849.1 - 0.03 14.3 0.2 0.056 13.4 0.2 1.4 1 0 0 1 1 1 0 YhfH-like protein Nbl1_Borealin_N PF10444.9 AAL63849.1 - 0.032 13.9 0.1 0.046 13.4 0.1 1.3 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal Coagulin PF02035.15 AAL63849.1 - 0.15 12.0 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 Coagulin Ribosomal_L3 PF00297.22 AAL63850.1 - 2.9e-77 260.1 0.0 7.9e-77 258.7 0.0 1.6 1 1 0 1 1 1 1 Ribosomal protein L3 Ribosomal_L4 PF00573.22 AAL63851.1 - 4.4e-41 140.7 0.0 5.2e-41 140.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_L23 PF00276.20 AAL63852.1 - 1.4e-15 57.4 6.9 1.2e-14 54.5 6.9 1.9 1 1 0 1 1 1 1 Ribosomal protein L23 TusA PF01206.17 AAL63852.1 - 0.035 13.9 0.9 0.044 13.6 0.9 1.3 1 1 0 1 1 1 0 Sulfurtransferase TusA SWI2_SNF2 PF18766.1 AAL63852.1 - 0.042 13.5 0.2 0.042 13.5 0.2 1.1 1 0 0 1 1 1 0 SWI2/SNF2 ATPase ResIII PF04851.15 AAL63852.1 - 0.077 13.0 0.5 0.081 12.9 0.5 1.0 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit adh_short PF00106.25 AAL63852.1 - 0.08 12.4 0.3 0.098 12.1 0.3 1.0 1 0 0 1 1 1 0 short chain dehydrogenase zf-ribbon_3 PF13248.6 AAL63854.1 - 6.2e-06 25.4 1.7 0.066 12.7 0.1 2.4 2 0 0 2 2 2 2 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 AAL63854.1 - 0.00022 21.1 0.6 0.00055 19.8 0.6 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain zinc_ribbon_2 PF13240.6 AAL63854.1 - 0.00028 20.5 4.4 0.071 12.8 0.5 2.4 2 0 0 2 2 2 2 zinc-ribbon domain DZR PF12773.7 AAL63854.1 - 0.00048 20.1 0.4 0.00092 19.2 0.4 1.4 1 0 0 1 1 1 1 Double zinc ribbon Nudix_N_2 PF14803.6 AAL63854.1 - 0.00049 20.0 1.9 0.043 13.7 0.1 2.4 2 0 0 2 2 2 1 Nudix N-terminal zf-ACC PF17848.1 AAL63854.1 - 0.0016 18.5 2.5 0.33 11.0 0.1 2.5 2 0 0 2 2 2 1 Acetyl-coA carboxylase zinc finger domain zf-NADH-PPase PF09297.11 AAL63854.1 - 0.0019 17.8 2.9 0.0075 15.9 2.9 2.0 1 1 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Zn-ribbon_8 PF09723.10 AAL63854.1 - 0.0031 17.6 3.8 0.028 14.5 3.8 2.3 1 1 0 1 1 1 1 Zinc ribbon domain DUF35_N PF12172.8 AAL63854.1 - 0.008 16.0 3.2 0.72 9.8 3.2 2.4 1 1 0 1 1 1 1 Rubredoxin-like zinc ribbon domain (DUF35_N) Auto_anti-p27 PF06677.12 AAL63854.1 - 0.011 15.9 2.8 0.021 15.0 2.8 1.5 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) NOB1_Zn_bind PF08772.11 AAL63854.1 - 0.013 15.7 1.1 0.037 14.2 0.3 2.1 3 0 0 3 3 2 0 Nin one binding (NOB1) Zn-ribbon like Prok-RING_1 PF14446.6 AAL63854.1 - 0.013 15.4 0.2 0.031 14.2 0.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 DNA_ligase_ZBD PF03119.16 AAL63854.1 - 0.014 15.4 4.9 1 9.5 0.1 3.2 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain zinc-ribbons_6 PF07191.12 AAL63854.1 - 0.023 14.7 0.2 0.046 13.7 0.2 1.4 1 0 0 1 1 1 0 zinc-ribbons TF_Zn_Ribbon PF08271.12 AAL63854.1 - 0.031 13.8 3.2 2.8 7.6 0.1 2.2 1 1 0 1 1 1 0 TFIIB zinc-binding EspB PF05802.11 AAL63854.1 - 0.034 14.2 0.2 0.047 13.7 0.2 1.1 1 0 0 1 1 1 0 Enterobacterial EspB protein zf-RING_7 PF02591.15 AAL63854.1 - 0.035 14.3 3.2 2 8.7 0.2 2.6 1 1 1 2 2 2 0 C4-type zinc ribbon domain zf-TFIIB PF13453.6 AAL63854.1 - 0.048 13.0 0.3 11 5.5 0.0 2.4 2 0 0 2 2 2 0 Transcription factor zinc-finger zinc_ribbon_4 PF13717.6 AAL63854.1 - 0.059 13.3 3.1 11 6.0 0.4 2.5 1 1 1 2 2 2 0 zinc-ribbon domain zf-C4_Topoisom PF01396.19 AAL63854.1 - 0.071 12.9 2.4 5.2 6.9 0.3 2.3 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger DUF1610 PF07754.11 AAL63854.1 - 0.093 12.7 5.4 0.81 9.7 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) Zn_ribbon_SprT PF17283.2 AAL63854.1 - 0.1 12.5 1.0 11 6.1 0.1 2.4 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-IS66 PF13005.7 AAL63854.1 - 0.14 12.6 1.6 20 5.7 0.1 2.6 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 zf-ISL3 PF14690.6 AAL63854.1 - 0.14 12.9 2.4 17 6.2 0.2 2.5 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HypA PF01155.19 AAL63854.1 - 0.15 12.0 0.2 0.34 11.0 0.2 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-LITAF-like PF10601.9 AAL63854.1 - 0.25 11.6 2.4 6.7 7.1 0.2 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain Ogr_Delta PF04606.12 AAL63854.1 - 0.26 11.3 2.4 12 6.0 0.2 2.4 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger A2L_zn_ribbon PF08792.10 AAL63854.1 - 0.29 10.9 1.3 12 5.8 0.2 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain PhnA_Zn_Ribbon PF08274.12 AAL63854.1 - 0.34 10.9 4.1 4.8 7.2 4.1 2.3 1 1 0 1 1 1 0 PhnA Zinc-Ribbon Zn_ribbon_recom PF13408.6 AAL63854.1 - 1.2 9.7 6.4 6.9 7.3 0.3 2.8 2 1 1 3 3 3 0 Recombinase zinc beta ribbon domain zf-tcix PF14952.6 AAL63854.1 - 1.5 8.5 6.8 3.7 7.2 0.8 2.3 1 1 1 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding Lar_restr_allev PF14354.6 AAL63854.1 - 3.4 8.1 5.1 7.5 7.0 3.5 2.3 2 1 0 2 2 2 0 Restriction alleviation protein Lar DUF2067 PF09840.9 AAL63855.1 - 5e-48 163.1 0.4 5.7e-48 163.0 0.4 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2067) HAUS-augmin3 PF14932.6 AAL63855.1 - 7.9e-05 22.4 0.3 0.0028 17.3 0.1 2.1 2 0 0 2 2 2 2 HAUS augmin-like complex subunit 3 DUF3524 PF12038.8 AAL63855.1 - 0.035 13.9 0.3 11 5.8 0.0 2.9 2 1 0 3 3 3 0 Domain of unknown function (DUF3524) RNA_pol_L_2 PF13656.6 AAL63856.1 - 5.5e-15 54.9 0.0 6.5e-15 54.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF1093 PF06486.11 AAL63856.1 - 0.0059 17.3 0.1 0.02 15.6 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1093) EMG1 PF03587.14 AAL63857.1 - 1.8e-42 145.2 0.0 2.1e-42 145.0 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Glyco_transf_4 PF13439.6 AAL63857.1 - 0.029 14.4 1.0 0.081 12.9 0.7 1.8 1 1 1 2 2 2 0 Glycosyltransferase Family 4 Peptidase_S8 PF00082.22 AAL63859.1 - 6e-05 22.4 0.0 8.4e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Subtilase family Peptidase_S8 PF00082.22 AAL63860.1 - 2.9e-38 131.8 2.7 3.3e-38 131.6 2.7 1.0 1 0 0 1 1 1 1 Subtilase family Aconitase PF00330.20 AAL63861.1 - 2.9e-78 263.9 1.5 1.2e-75 255.3 1.5 2.7 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) DUF521 PF04412.13 AAL63861.1 - 9.1e-05 21.3 0.0 0.00014 20.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF521) OTCace PF00185.24 AAL63862.1 - 3.9e-56 189.5 0.1 1.2e-54 184.6 0.0 2.0 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 AAL63862.1 - 5.4e-42 143.3 0.1 8.3e-42 142.7 0.1 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain GSH-S_N PF02951.14 AAL63862.1 - 0.082 13.0 0.2 0.29 11.3 0.1 1.9 2 1 0 2 2 2 0 Prokaryotic glutathione synthetase, N-terminal domain HMGL-like PF00682.19 AAL63863.1 - 4.2e-64 216.6 1.9 4.2e-64 216.6 1.9 1.6 2 0 0 2 2 2 1 HMGL-like AsnC_trans_reg PF01037.21 AAL63863.1 - 4.7e-17 61.7 0.6 1.7e-16 59.9 0.6 2.1 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain TRAPP PF04051.16 AAL63863.1 - 0.002 17.9 0.1 0.0041 16.9 0.1 1.5 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component NapD PF03927.13 AAL63863.1 - 0.024 14.7 2.3 0.089 12.9 1.0 2.7 2 0 0 2 2 2 0 NapD protein CinA_KH PF18146.1 AAL63863.1 - 0.048 13.8 0.5 3.2 8.0 0.0 3.3 2 1 1 3 3 3 0 Damage-inducible protein CinA KH domain AP_endonuc_2 PF01261.24 AAL63863.1 - 0.084 12.3 0.1 1.6 8.1 0.0 2.7 2 1 1 3 3 3 0 Xylose isomerase-like TIM barrel ACT_4 PF13291.6 AAL63863.1 - 0.093 13.3 5.5 0.11 13.1 1.6 2.8 2 1 1 3 3 3 0 ACT domain AlkA_N PF06029.11 AAL63863.1 - 0.11 12.8 1.3 4.3 7.6 0.1 2.7 3 0 0 3 3 3 0 AlkA N-terminal domain PAPS_reduct PF01507.19 AAL63864.1 - 4.5e-39 134.3 0.0 9e-39 133.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Fer4_21 PF14697.6 AAL63864.1 - 6.4e-06 26.2 6.6 6.4e-06 26.2 6.6 1.9 2 1 0 2 2 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AAL63864.1 - 1e-05 26.0 8.1 3e-05 24.5 8.1 1.9 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 AAL63864.1 - 5.5e-05 23.1 12.5 0.00036 20.5 0.8 2.9 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4 PF00037.27 AAL63864.1 - 6.4e-05 22.6 16.7 8.9e-05 22.1 1.9 2.7 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_9 PF13187.6 AAL63864.1 - 0.00015 21.8 7.8 0.00015 21.8 7.8 1.8 2 0 0 2 2 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAL63864.1 - 0.00026 21.1 11.6 0.0018 18.3 11.0 2.5 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAL63864.1 - 0.00039 20.4 1.8 0.00039 20.4 1.8 3.0 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_18 PF13746.6 AAL63864.1 - 0.0017 18.5 2.4 0.004 17.4 2.4 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAL63864.1 - 0.0021 19.0 10.8 0.013 16.5 0.5 3.1 2 1 0 3 3 3 1 4Fe-4S double cluster binding domain Fer4_8 PF13183.6 AAL63864.1 - 0.019 15.4 7.0 0.23 11.9 1.1 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 AAL63864.1 - 1.5 9.4 13.0 0.29 11.7 2.2 2.7 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_17 PF13534.6 AAL63864.1 - 3.1 8.4 12.3 4.7 7.8 2.8 2.8 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 AAL63864.1 - 7.4 7.8 24.4 0.12 13.4 3.6 2.9 3 0 0 3 3 2 0 4Fe-4S binding domain Peptidase_M54 PF07998.11 AAL63865.1 - 1.4e-25 90.4 0.0 1.9e-25 90.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M54 Peptidase_M10 PF00413.24 AAL63865.1 - 0.0016 18.3 0.0 0.0016 18.3 0.0 1.2 1 0 0 1 1 1 1 Matrixin Peptidase_M43 PF05572.13 AAL63865.1 - 0.0084 16.0 0.0 0.027 14.4 0.0 1.7 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Peptidase_M66 PF10462.9 AAL63865.1 - 0.026 13.5 0.0 0.034 13.1 0.0 1.1 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_5 PF13688.6 AAL63865.1 - 0.045 13.9 0.0 0.051 13.7 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 AAL63865.1 - 0.088 12.4 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Cys_rich_KTR PF14205.6 AAL63865.1 - 0.12 12.2 0.4 0.3 10.9 0.2 1.7 2 0 0 2 2 2 0 Cysteine-rich KTR HscB_4_cys PF18256.1 AAL63865.1 - 0.25 11.2 0.2 0.25 11.2 0.2 2.1 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif Aconitase_C PF00694.19 AAL63866.1 - 1.1e-16 61.4 0.0 1.4e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 Aconitase C-terminal domain HMGL-like PF00682.19 AAL63867.1 - 7.3e-81 271.6 3.8 9.8e-81 271.2 3.8 1.2 1 0 0 1 1 1 1 HMGL-like AP_endonuc_2 PF01261.24 AAL63867.1 - 0.002 17.6 0.8 0.0072 15.8 0.6 2.1 1 1 1 2 2 2 1 Xylose isomerase-like TIM barrel Glyco_hydro_97 PF10566.9 AAL63867.1 - 0.0096 15.2 0.3 0.033 13.5 0.1 1.8 2 1 1 3 3 3 1 Glycoside hydrolase 97 Pro_dh PF01619.18 AAL63867.1 - 0.048 13.2 0.1 0.072 12.6 0.1 1.3 1 0 0 1 1 1 0 Proline dehydrogenase PTE PF02126.18 AAL63867.1 - 0.053 12.9 0.1 0.12 11.8 0.0 1.7 2 0 0 2 2 2 0 Phosphotriesterase family TPP_enzyme_C PF02775.21 AAL63867.1 - 0.066 13.0 0.7 2.3 8.0 0.1 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain SpoU_sub_bind PF08032.12 AAL63867.1 - 0.083 13.2 0.6 11 6.4 0.2 3.1 2 1 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding IMPDH PF00478.25 AAL63867.1 - 1.4 7.9 4.7 0.16 10.9 0.5 1.7 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Iso_dh PF00180.20 AAL63868.1 - 3.6e-80 269.7 0.4 4.4e-80 269.4 0.4 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF166 PF02593.14 AAL63868.1 - 0.046 13.3 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function PdxA PF04166.12 AAL63868.1 - 0.092 12.1 0.1 0.18 11.2 0.1 1.4 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthetic protein PdxA ELFV_dehydrog PF00208.21 AAL63869.1 - 1e-65 221.9 0.1 1.3e-65 221.5 0.1 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 AAL63869.1 - 2.3e-51 173.0 0.0 3.6e-51 172.4 0.0 1.3 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 2-Hacid_dh_C PF02826.19 AAL63869.1 - 0.0041 16.5 0.2 0.0091 15.4 0.2 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Bac_GDH PF05088.12 AAL63869.1 - 0.038 11.5 0.0 0.053 11.0 0.0 1.1 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase PALP PF00291.25 AAL63869.1 - 0.079 12.4 0.2 0.13 11.6 0.2 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme DUF3420 PF11900.8 AAL63870.1 - 0.035 14.2 0.3 0.69 10.1 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3420) WLM PF08325.10 AAL63871.1 - 0.11 12.5 0.1 0.22 11.6 0.1 1.5 1 1 0 1 1 1 0 WLM domain BPD_transp_1 PF00528.22 AAL63872.1 - 2.2e-15 56.9 10.7 2.2e-15 56.9 10.7 1.4 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component BofA PF07441.11 AAL63872.1 - 0.036 14.3 3.5 0.096 12.9 0.4 2.4 1 1 0 2 2 2 0 SigmaK-factor processing regulatory protein BofA Deltameth_res PF16020.5 AAL63872.1 - 0.96 9.4 3.8 0.45 10.4 0.2 2.2 2 0 0 2 2 2 0 Deltamethrin resistance ABC_tran PF00005.27 AAL63873.1 - 4.7e-37 127.6 0.0 6.2e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAL63873.1 - 4.5e-12 46.4 0.6 2.6e-07 30.8 0.0 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAL63873.1 - 3.5e-09 36.4 0.0 1.4e-07 31.2 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAL63873.1 - 4.5e-05 23.1 0.0 8.5e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AAL63873.1 - 0.00035 20.9 0.9 0.0096 16.2 0.9 2.5 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.18 AAL63873.1 - 0.00054 19.4 0.1 0.0015 18.0 0.0 1.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_16 PF13191.6 AAL63873.1 - 0.00057 20.3 0.1 0.0015 18.9 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 AAL63873.1 - 0.0017 18.1 0.0 0.004 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AAL63873.1 - 0.0027 17.8 0.0 0.0057 16.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 AAL63873.1 - 0.0029 17.4 0.0 0.059 13.1 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 AAL63873.1 - 0.0031 18.0 0.0 0.0071 16.9 0.0 1.6 1 1 1 2 2 1 1 AAA domain IstB_IS21 PF01695.17 AAL63873.1 - 0.0035 17.1 0.1 0.97 9.1 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein RsgA_GTPase PF03193.16 AAL63873.1 - 0.0057 16.6 0.1 0.013 15.4 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase T2SSE PF00437.20 AAL63873.1 - 0.0061 15.6 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein SbcCD_C PF13558.6 AAL63873.1 - 0.0072 16.5 0.1 0.11 12.8 0.1 2.6 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF87 PF01935.17 AAL63873.1 - 0.0081 16.3 0.1 0.02 15.0 0.1 1.6 2 0 0 2 2 2 1 Helicase HerA, central domain AAA PF00004.29 AAL63873.1 - 0.013 16.0 0.1 0.22 12.0 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 AAL63873.1 - 0.015 15.3 0.2 0.033 14.1 0.0 1.7 2 0 0 2 2 1 0 NACHT domain AAA_25 PF13481.6 AAL63873.1 - 0.015 14.9 0.6 0.15 11.7 0.6 2.4 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 AAL63873.1 - 0.021 14.8 1.3 1.8 8.6 0.1 3.1 2 2 2 4 4 4 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 AAL63873.1 - 0.022 14.5 0.2 0.082 12.6 0.2 1.9 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 AAL63873.1 - 0.022 14.6 0.1 0.083 12.8 0.1 1.9 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea ABC_ATPase PF09818.9 AAL63873.1 - 0.025 13.4 0.1 1.8 7.3 0.0 2.7 2 1 0 2 2 2 0 Predicted ATPase of the ABC class MMR_HSR1 PF01926.23 AAL63873.1 - 0.03 14.4 0.0 0.06 13.4 0.0 1.7 2 0 0 2 2 1 0 50S ribosome-binding GTPase CobU PF02283.16 AAL63873.1 - 0.035 13.7 0.2 2.1 7.9 0.0 2.2 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Pox_A32 PF04665.12 AAL63873.1 - 0.042 13.3 0.0 0.071 12.6 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_7 PF12775.7 AAL63873.1 - 0.049 13.2 0.0 0.076 12.5 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 AAL63873.1 - 0.052 14.1 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 AAL63873.1 - 0.054 12.4 0.0 0.1 11.5 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.19 AAL63873.1 - 0.06 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Mg_chelatase PF01078.21 AAL63873.1 - 0.073 12.4 0.1 0.26 10.6 0.0 1.8 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 AAL63873.1 - 0.076 13.3 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Adeno_IVa2 PF02456.15 AAL63873.1 - 0.08 11.7 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein ATP_bind_1 PF03029.17 AAL63873.1 - 0.09 12.5 0.1 0.27 11.0 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.6 AAL63873.1 - 0.11 12.9 0.0 0.18 12.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 AAL63873.1 - 0.15 11.9 0.7 1.7 8.6 0.2 2.5 2 1 0 2 2 2 0 NTPase RNA_helicase PF00910.22 AAL63873.1 - 0.16 12.4 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase DEAD PF00270.29 AAL63873.1 - 0.16 11.7 0.0 0.32 10.8 0.0 1.5 1 1 0 1 1 1 0 DEAD/DEAH box helicase G-alpha PF00503.20 AAL63873.1 - 0.17 11.0 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_14 PF13173.6 AAL63873.1 - 0.17 11.9 0.1 1.8 8.6 0.1 2.4 2 1 1 3 3 3 0 AAA domain ResIII PF04851.15 AAL63873.1 - 0.2 11.7 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PPV_E1_C PF00519.17 AAL63873.1 - 0.27 10.0 0.0 0.37 9.6 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase Molybdopterin PF00384.22 AAL63874.1 - 1.9e-23 83.1 0.0 8.6e-10 38.1 0.0 3.0 3 0 0 3 3 3 3 Molybdopterin oxidoreductase Molydop_binding PF01568.21 AAL63874.1 - 0.0012 18.8 0.0 0.0037 17.3 0.0 1.8 1 1 0 1 1 1 1 Molydopterin dinucleotide binding domain TatD_DNase PF01026.21 AAL63875.1 - 3.6e-44 151.1 0.0 4.1e-44 150.9 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Metallophos PF00149.28 AAL63876.1 - 6.5e-22 79.0 0.0 8.3e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AAL63876.1 - 5.3e-06 26.7 0.1 0.0098 16.1 0.0 2.0 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Ntox22 PF15527.6 AAL63877.1 - 0.23 11.5 2.5 0.26 11.4 0.1 2.3 3 0 0 3 3 3 0 Bacterial toxin 22 dUTPase PF00692.19 AAL63879.1 - 4.6e-19 68.4 0.0 2.1e-18 66.3 0.0 1.8 1 1 1 2 2 2 1 dUTPase DCD PF06559.11 AAL63879.1 - 0.00072 18.4 0.0 0.0052 15.6 0.0 2.5 1 1 0 1 1 1 1 2'-deoxycytidine 5'-triphosphate deaminase (DCD) TcpE PF12648.7 AAL63880.1 - 5.9 7.5 6.9 1.6 9.3 2.9 1.9 1 1 1 2 2 2 0 TcpE family ThiS PF02597.20 AAL63881.1 - 1.2e-08 35.5 0.0 1.2e-08 35.4 0.0 1.0 1 0 0 1 1 1 1 ThiS family Urm1 PF09138.11 AAL63881.1 - 0.0015 18.9 0.0 0.0018 18.6 0.0 1.3 1 1 0 1 1 1 1 Urm1 (Ubiquitin related modifier) DNA_binding_1 PF01035.20 AAL63882.1 - 1.4e-22 79.6 0.0 2e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Fer4_15 PF13459.6 AAL63883.1 - 8e-10 39.3 0.0 9.1e-10 39.1 0.0 1.0 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_13 PF13370.6 AAL63883.1 - 3.9e-07 30.5 0.0 5.2e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_19 PF06902.11 AAL63883.1 - 5.6e-05 23.1 0.0 0.00012 22.0 0.0 1.5 1 1 0 1 1 1 1 Divergent 4Fe-4S mono-cluster Flp1_like PF16982.5 AAL63884.1 - 0.0015 17.9 3.0 0.0037 16.6 2.1 1.8 1 1 1 2 2 2 1 Putative Flagellin, Flp1-like, domain VIT1 PF01988.19 AAL63884.1 - 0.016 15.1 1.7 0.017 15.0 1.7 1.0 1 0 0 1 1 1 0 VIT family DUF3852 PF12963.7 AAL63884.1 - 0.069 13.5 2.0 0.075 13.4 2.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3852) Ribosomal_S5_C PF03719.15 AAL63884.1 - 0.073 12.5 0.2 0.085 12.3 0.2 1.2 1 0 0 1 1 1 0 Ribosomal protein S5, C-terminal domain Hydrolase_3 PF08282.12 AAL63885.1 - 4.9e-10 39.6 0.0 8.8e-10 38.7 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAL63885.1 - 6.2e-07 29.9 0.3 2.8e-05 24.5 0.3 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AAL63885.1 - 3e-05 24.5 0.3 6.2e-05 23.5 0.3 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase 3HCDH_RFF PF18321.1 AAL63885.1 - 0.018 15.5 0.1 0.077 13.5 0.1 2.1 2 0 0 2 2 2 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain HAD_2 PF13419.6 AAL63885.1 - 0.039 14.1 0.0 0.087 12.9 0.0 1.6 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase PhoU PF01895.19 AAL63886.1 - 1.2e-12 48.1 3.9 2.5e-10 40.7 0.7 2.8 3 0 0 3 3 3 2 PhoU domain MazE_antitoxin PF04014.18 AAL63886.1 - 1.2e-07 31.5 0.8 3.1e-07 30.2 0.2 2.1 2 0 0 2 2 2 1 Antidote-toxin recognition MazE, bacterial antitoxin SymE_toxin PF08845.10 AAL63886.1 - 0.021 14.9 0.1 0.038 14.0 0.1 1.4 1 0 0 1 1 1 0 Toxin SymE, type I toxin-antitoxin system DUF502 PF04367.13 AAL63886.1 - 0.034 14.0 0.1 0.65 9.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF502) DUF1664 PF07889.12 AAL63886.1 - 0.086 12.9 0.6 0.5 10.4 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF1614 PF07758.11 AAL63887.1 - 8.8e-46 156.0 14.6 8.8e-46 156.0 14.6 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF1614) DMRL_synthase PF00885.19 AAL63888.1 - 5.1e-09 36.1 0.0 6.3e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase RHH_1 PF01402.21 AAL63889.1 - 3.7e-07 29.8 0.1 7.7e-07 28.8 0.1 1.6 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family NikR_C PF08753.11 AAL63889.1 - 2.3e-06 27.7 0.8 1.4e-05 25.1 0.0 2.4 2 1 1 3 3 3 1 NikR C terminal nickel binding domain RHH_3 PF12651.7 AAL63889.1 - 2.9e-06 27.1 0.1 5.2e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 Ribbon-helix-helix domain RHH_5 PF07878.11 AAL63889.1 - 8.7e-05 22.3 0.6 0.00012 21.9 0.6 1.2 1 0 0 1 1 1 1 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 PSK_trans_fac PF07704.11 AAL63889.1 - 0.00075 20.2 0.0 0.0011 19.7 0.0 1.3 1 0 0 1 1 1 1 Rv0623-like transcription factor VapB_antitoxin PF09957.9 AAL63889.1 - 0.13 12.2 0.1 0.22 11.5 0.1 1.4 1 0 0 1 1 1 0 Bacterial antitoxin of type II TA system, VapB Prok-JAB PF14464.6 AAL63890.1 - 1.7e-16 60.1 0.1 1.9e-16 59.9 0.1 1.0 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Peptidase_M24 PF00557.24 AAL63891.1 - 2e-55 187.8 0.0 2.9e-55 187.2 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 AAL63891.1 - 4.6e-07 30.6 0.0 9.3e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Hydantoinase_B PF02538.14 AAL63893.1 - 3.1e-188 626.4 0.2 3.5e-188 626.2 0.2 1.0 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 AAL63894.1 - 2e-101 339.1 3.1 5.8e-101 337.6 0.7 2.0 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 AAL63894.1 - 4.3e-51 173.1 0.0 6.9e-51 172.5 0.0 1.3 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase N-terminal region MarR_2 PF12802.7 AAL63894.1 - 0.12 12.3 0.3 20 5.2 0.0 3.8 4 0 0 4 4 4 0 MarR family GYD PF08734.11 AAL63895.1 - 1.3e-27 95.6 0.0 1.4e-27 95.4 0.0 1.0 1 0 0 1 1 1 1 GYD domain DUF86 PF01934.17 AAL63896.1 - 5.6e-19 68.2 0.0 6.4e-19 68.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF86 Polbeta PF18765.1 AAL63897.1 - 0.0094 16.0 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase FAD-oxidase_C PF02913.19 AAL63898.1 - 5.2e-49 167.1 0.0 7.9e-49 166.5 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 AAL63898.1 - 6.6e-42 142.5 0.7 1.3e-41 141.5 0.7 1.5 1 0 0 1 1 1 1 FAD binding domain DUF58 PF01882.18 AAL63900.1 - 2.2e-16 59.9 0.0 4.3e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF58 AAA_3 PF07726.11 AAL63901.1 - 5e-63 210.8 0.0 6.8e-63 210.4 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 AAL63901.1 - 1.8e-19 69.4 0.3 3.2e-19 68.5 0.3 1.4 1 0 0 1 1 1 1 AAA lid domain AAA_5 PF07728.14 AAL63901.1 - 2.6e-15 56.6 0.0 5e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 AAL63901.1 - 7.4e-10 38.8 0.0 5.6e-07 29.4 0.0 2.2 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 AAL63901.1 - 1.1e-07 32.4 0.0 1.9e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MCM PF00493.23 AAL63901.1 - 0.00021 20.5 0.0 0.00097 18.3 0.0 2.0 1 1 0 1 1 1 1 MCM P-loop domain Sigma54_activat PF00158.26 AAL63901.1 - 0.00039 20.2 0.0 0.0089 15.7 0.0 2.1 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 AAL63901.1 - 0.0012 18.3 0.3 0.23 10.8 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 AAL63901.1 - 0.0041 17.7 0.0 0.0099 16.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain SKI PF01202.22 AAL63901.1 - 0.066 13.3 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase Rad17 PF03215.15 AAL63901.1 - 0.081 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_2 PF07724.14 AAL63901.1 - 0.12 12.5 0.0 0.44 10.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) MCM_lid PF17855.1 AAL63901.1 - 0.13 12.7 0.0 0.34 11.3 0.0 1.7 1 1 0 1 1 1 0 MCM AAA-lid domain TsaE PF02367.17 AAL63901.1 - 0.16 12.0 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE YwiC PF14256.6 AAL63902.1 - 0.012 15.9 7.7 0.012 15.9 7.7 3.0 2 1 1 3 3 3 0 YwiC-like protein MFS_1 PF07690.16 AAL63902.1 - 0.26 10.2 33.7 0.69 8.8 7.9 2.6 1 1 1 2 2 2 0 Major Facilitator Superfamily PLA2_B PF01735.18 AAL63902.1 - 0.28 9.5 0.2 0.39 9.1 0.2 1.1 1 0 0 1 1 1 0 Lysophospholipase catalytic domain DUF751 PF05421.11 AAL63902.1 - 1.8 9.3 16.4 0.33 11.7 0.8 4.4 3 2 2 5 5 5 0 Protein of unknown function (DUF751) Transglut_core PF01841.19 AAL63903.1 - 9.6e-21 74.3 0.0 1.5e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF4129 PF13559.6 AAL63903.1 - 3.5e-05 24.0 2.0 0.00011 22.4 2.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) Transglut_core3 PF13471.6 AAL63903.1 - 0.00042 20.2 0.4 0.001 19.0 0.1 1.8 2 0 0 2 2 2 1 Transglutaminase-like superfamily PEGA PF08308.11 AAL63903.1 - 0.015 15.2 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 PEGA domain HTH_24 PF13412.6 AAL63904.1 - 1.3e-08 34.3 0.1 5.9e-08 32.2 0.0 2.0 2 1 0 2 2 2 1 Winged helix-turn-helix DNA-binding TrmB PF01978.19 AAL63904.1 - 1e-06 28.5 0.3 2.3e-06 27.4 0.1 1.7 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 AAL63904.1 - 1.4e-05 24.9 0.0 0.00037 20.3 0.0 2.1 2 0 0 2 2 2 1 MarR family HTH_11 PF08279.12 AAL63904.1 - 4.3e-05 23.4 0.0 0.00035 20.4 0.0 2.0 2 0 0 2 2 2 1 HTH domain MarR PF01047.22 AAL63904.1 - 6e-05 22.9 0.0 0.00048 20.0 0.0 2.1 2 1 0 2 2 2 1 MarR family HTH_AsnC-type PF13404.6 AAL63904.1 - 0.00086 19.1 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain DprA_WH PF17782.1 AAL63904.1 - 0.0013 18.8 0.0 0.0024 18.0 0.0 1.4 1 0 0 1 1 1 1 DprA winged helix domain HTH_IclR PF09339.10 AAL63904.1 - 0.0014 18.4 0.0 0.0035 17.1 0.0 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain FaeA PF04703.12 AAL63904.1 - 0.0028 18.0 0.0 0.0054 17.1 0.0 1.5 1 0 0 1 1 1 1 FaeA-like protein HTH_41 PF14502.6 AAL63904.1 - 0.0034 17.1 0.0 0.007 16.0 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_20 PF12840.7 AAL63904.1 - 0.0093 16.0 0.0 0.052 13.6 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_5 PF01022.20 AAL63904.1 - 0.02 14.7 0.0 0.058 13.3 0.0 1.7 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family GntR PF00392.21 AAL63904.1 - 0.028 14.1 0.2 5.4 6.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_27 PF13463.6 AAL63904.1 - 0.054 14.0 0.0 0.79 10.3 0.0 2.1 2 0 0 2 2 2 0 Winged helix DNA-binding domain Penicillinase_R PF03965.16 AAL63904.1 - 0.058 13.7 0.0 0.15 12.4 0.0 1.7 1 1 1 2 2 2 0 Penicillinase repressor HTH_45 PF14947.6 AAL63904.1 - 0.068 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix PaaX PF07848.12 AAL63904.1 - 0.069 13.4 0.4 1.8 8.9 0.1 2.1 1 1 1 2 2 2 0 PaaX-like protein Rrf2 PF02082.20 AAL63904.1 - 0.087 13.2 0.0 0.22 11.9 0.0 1.7 2 1 0 2 2 2 0 Transcriptional regulator ATPase PF06745.13 AAL63905.1 - 4.8e-12 45.7 0.0 3.8e-07 29.7 0.0 2.3 2 0 0 2 2 2 2 KaiC AAA PF00004.29 AAL63905.1 - 1.7e-07 31.7 0.0 3.2e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 AAL63905.1 - 1.1e-05 25.2 0.1 2.7e-05 23.9 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 AAL63905.1 - 0.00013 22.0 0.0 0.00075 19.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 AAL63905.1 - 0.00015 21.5 0.1 0.13 12.0 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_24 PF13479.6 AAL63905.1 - 0.00053 19.8 0.0 0.0018 18.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain RecA PF00154.21 AAL63905.1 - 0.00056 19.5 0.0 0.00091 18.8 0.0 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_16 PF13191.6 AAL63905.1 - 0.0006 20.2 0.0 0.0014 19.0 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 AAL63905.1 - 0.00064 19.7 0.0 0.0016 18.4 0.0 1.6 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 AAL63905.1 - 0.00085 19.6 0.0 0.003 17.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 AAL63905.1 - 0.0039 17.6 0.0 0.0059 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 AAL63905.1 - 0.0057 17.2 0.1 0.0094 16.5 0.1 1.2 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 AAL63905.1 - 0.008 15.9 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 AAL63905.1 - 0.012 15.4 0.0 0.018 14.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 AAL63905.1 - 0.019 15.0 0.0 0.059 13.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain RNA12 PF10443.9 AAL63905.1 - 0.022 13.5 0.0 0.027 13.2 0.0 1.1 1 0 0 1 1 1 0 RNA12 protein CobU PF02283.16 AAL63905.1 - 0.039 13.5 0.0 0.079 12.5 0.0 1.5 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_18 PF13238.6 AAL63905.1 - 0.046 14.3 0.0 0.097 13.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain KdpD PF02702.17 AAL63905.1 - 0.052 13.0 0.0 0.078 12.4 0.0 1.2 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain PhoH PF02562.16 AAL63905.1 - 0.055 12.9 0.0 0.091 12.2 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 AAL63905.1 - 0.07 13.0 0.0 0.51 10.2 0.0 2.3 2 1 0 2 2 2 0 NACHT domain TIP49 PF06068.13 AAL63905.1 - 0.086 12.0 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain SMC_N PF02463.19 AAL63905.1 - 0.17 11.3 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain NTPase_1 PF03266.15 AAL63905.1 - 0.18 11.7 0.0 0.52 10.2 0.0 1.6 1 1 0 1 1 1 0 NTPase AAA_29 PF13555.6 AAL63905.1 - 0.18 11.5 0.0 0.38 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2075 PF09848.9 AAL63905.1 - 0.27 10.4 0.1 0.37 10.0 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 AAL63907.1 - 4e-06 26.4 0.0 0.0022 17.4 0.0 2.5 1 1 1 2 2 2 2 KaiC AAA_24 PF13479.6 AAL63907.1 - 5.4e-05 23.0 0.0 0.00014 21.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 AAL63907.1 - 6.4e-05 22.6 0.0 0.00015 21.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAL63907.1 - 6.8e-05 23.3 0.0 0.00013 22.4 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 AAL63907.1 - 7.6e-05 23.2 0.0 0.00017 22.0 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) GvpD PF07088.11 AAL63907.1 - 0.00047 18.9 0.0 0.37 9.4 0.0 2.1 2 0 0 2 2 2 2 GvpD gas vesicle protein AAA_22 PF13401.6 AAL63907.1 - 0.00074 19.8 0.0 0.0013 19.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 AAL63907.1 - 0.0019 18.0 0.0 0.0028 17.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 AAL63907.1 - 0.0027 17.6 0.0 0.005 16.8 0.0 1.6 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_5 PF07728.14 AAL63907.1 - 0.0056 16.7 0.0 0.0097 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 AAL63907.1 - 0.01 15.6 0.2 0.041 13.6 0.0 2.0 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 AAL63907.1 - 0.016 15.8 0.0 0.032 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 AAL63907.1 - 0.019 14.9 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain CobU PF02283.16 AAL63907.1 - 0.02 14.5 0.0 0.047 13.3 0.0 1.6 1 1 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_17 PF13207.6 AAL63907.1 - 0.02 15.3 0.0 0.04 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 AAL63907.1 - 0.039 14.2 0.0 0.059 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AAL63907.1 - 0.048 14.2 0.0 0.086 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 AAL63907.1 - 0.061 12.5 0.0 0.091 12.0 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain RNA_helicase PF00910.22 AAL63907.1 - 0.07 13.5 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 AAL63907.1 - 0.071 12.9 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mg_chelatase PF01078.21 AAL63907.1 - 0.11 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 AAL63907.1 - 0.11 12.8 0.0 0.57 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 AAL63907.1 - 0.13 11.3 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2075 PF09848.9 AAL63907.1 - 0.19 10.9 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RecA PF00154.21 AAL63907.1 - 0.19 11.2 0.0 0.43 10.0 0.0 1.5 1 0 0 1 1 1 0 recA bacterial DNA recombination protein AAA_33 PF13671.6 AAL63907.1 - 0.21 11.8 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain TatD_DNase PF01026.21 AAL63908.1 - 4.4e-27 95.1 0.0 5.3e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase ADH_N PF08240.12 AAL63909.1 - 4.3e-19 68.4 0.0 8.3e-19 67.5 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AAL63909.1 - 3.1e-18 66.0 0.2 6.8e-18 64.9 0.1 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.6 AAL63909.1 - 0.00019 21.2 0.2 0.00096 19.0 0.0 1.9 1 1 0 2 2 2 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 AAL63909.1 - 0.017 16.2 0.0 0.032 15.3 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 AAL63909.1 - 0.11 13.2 0.0 0.24 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain AFOR_C PF01314.18 AAL63910.1 - 3.7e-104 348.8 0.0 4.3e-104 348.6 0.0 1.1 1 0 0 1 1 1 1 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 AFOR_N PF02730.15 AAL63910.1 - 5.6e-72 241.8 0.2 1.2e-71 240.7 0.2 1.4 1 0 0 1 1 1 1 Aldehyde ferredoxin oxidoreductase, N-terminal domain DegT_DnrJ_EryC1 PF01041.17 AAL63911.1 - 4.4e-114 381.6 0.9 1.6e-113 379.7 0.9 1.7 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 AAL63911.1 - 4.5e-07 29.1 0.5 9.6e-07 28.1 0.4 1.5 2 0 0 2 2 2 1 Aminotransferase class-V TFIIF_beta PF02270.15 AAL63911.1 - 1.4e-05 25.1 0.6 0.053 13.7 0.1 3.1 3 0 0 3 3 3 2 TFIIF, beta subunit HTH domain Beta_elim_lyase PF01212.21 AAL63911.1 - 0.0029 16.9 0.2 0.004 16.5 0.2 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 AAL63911.1 - 0.003 16.2 0.1 0.0041 15.7 0.1 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme ALS_ss_C PF10369.9 AAL63911.1 - 0.037 14.2 0.1 0.1 12.8 0.1 1.7 1 0 0 1 1 1 0 Small subunit of acetolactate synthase DUF4516 PF14990.6 AAL63912.1 - 0.13 12.1 0.0 0.13 12.1 0.0 2.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4516) Abhydrolase_9_N PF15420.6 AAL63912.1 - 0.26 11.3 10.8 0.42 10.6 7.8 2.0 1 1 1 2 2 2 0 Alpha/beta-hydrolase family N-terminus Phage_holin_3_6 PF07332.11 AAL63912.1 - 7.8 6.6 20.8 8.7 6.4 11.5 2.7 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III FeS_assembly_P PF01883.19 AAL63913.1 - 6.7e-18 64.6 2.4 8.8e-18 64.2 2.4 1.2 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein BET PF17035.5 AAL63913.1 - 0.092 12.9 0.1 14 5.9 0.0 2.2 2 0 0 2 2 2 0 Bromodomain extra-terminal - transcription regulation TusA PF01206.17 AAL63914.1 - 1.9e-11 43.6 0.0 2.1e-11 43.5 0.0 1.0 1 0 0 1 1 1 1 Sulfurtransferase TusA UPF0175 PF03683.13 AAL63915.1 - 0.011 15.4 0.0 0.013 15.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) SinI PF08671.10 AAL63916.1 - 0.0021 17.8 2.1 0.0032 17.2 2.1 1.4 1 0 0 1 1 1 1 Anti-repressor SinI Flavin_Reduct PF01613.18 AAL63917.1 - 5.1e-25 88.3 0.0 5.7e-25 88.2 0.0 1.0 1 0 0 1 1 1 1 Flavin reductase like domain VWA_CoxE PF05762.14 AAL63918.1 - 1.7e-07 30.9 0.2 3.8e-07 29.7 0.0 1.7 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein VWA_2 PF13519.6 AAL63918.1 - 1.2e-05 25.9 0.1 3.8e-05 24.3 0.1 1.9 1 1 0 1 1 1 1 von Willebrand factor type A domain REV1_C PF16727.5 AAL63918.1 - 0.032 14.6 0.2 4.6 7.7 0.0 2.8 2 0 0 2 2 2 0 DNA repair protein REV1 C-terminal domain Fe_dep_repr_C PF02742.15 AAL63918.1 - 0.097 12.8 0.0 0.3 11.2 0.0 1.8 2 0 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain VWA PF00092.28 AAL63918.1 - 0.12 12.6 0.2 0.4 10.9 0.2 1.8 1 1 0 1 1 1 0 von Willebrand factor type A domain Pilin_N PF07790.11 AAL63920.1 - 0.026 15.4 0.4 0.041 14.8 0.4 1.5 1 1 0 1 1 1 0 Archaeal Type IV pilin, N-terminal DUF1180 PF06679.12 AAL63920.1 - 0.038 14.4 2.3 0.046 14.1 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF2749 PF10907.8 AAL63920.1 - 3.4 7.9 7.0 19 5.5 7.0 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2749) PaRep2b PF07775.11 AAL63921.1 - 1.7e-26 92.8 1.7 8.1e-13 47.7 0.8 2.0 1 1 1 2 2 2 2 PaRep2b protein B2-adapt-app_C PF09066.10 AAL63921.1 - 0.18 11.9 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain PaRep2b PF07775.11 AAL63922.1 - 0.00011 20.8 0.2 0.00012 20.7 0.2 1.0 1 0 0 1 1 1 1 PaRep2b protein Acyl-CoA_dh_1 PF00441.24 AAL63924.1 - 2.1e-35 122.1 2.7 3.3e-35 121.5 2.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 AAL63924.1 - 8.1e-20 71.6 0.1 2.6e-19 69.9 0.1 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 AAL63924.1 - 3.5e-18 65.6 0.0 6.8e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 AAL63924.1 - 3.9e-16 59.6 1.6 6e-16 58.9 1.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Pribosyltran PF00156.27 AAL63925.1 - 4.1e-15 55.7 0.1 6.2e-15 55.1 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain HTH_3 PF01381.22 AAL63925.1 - 1.1e-08 35.0 0.1 2.2e-08 34.0 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 AAL63925.1 - 0.0025 18.1 0.0 0.0069 16.7 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain Glyco_tranf_2_3 PF13641.6 AAL63925.1 - 0.038 13.9 0.0 0.083 12.8 0.0 1.6 2 0 0 2 2 2 0 Glycosyltransferase like family 2 UPRTase PF14681.6 AAL63925.1 - 0.057 12.9 0.0 0.09 12.2 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase RNase_HII PF01351.18 AAL63925.1 - 0.062 13.1 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease HII Sigma70_r4_2 PF08281.12 AAL63925.1 - 0.065 12.9 0.2 0.43 10.3 0.0 2.2 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_26 PF13443.6 AAL63925.1 - 0.11 13.0 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain PRTase_2 PF15609.6 AAL63925.1 - 0.13 11.8 0.0 0.25 10.8 0.0 1.6 2 0 0 2 2 2 0 Phosphoribosyl transferase HTH_24 PF13412.6 AAL63925.1 - 0.13 11.8 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Phage_CI_repr PF07022.13 AAL63925.1 - 0.17 12.0 0.0 0.33 11.1 0.0 1.6 1 1 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain CBS PF00571.28 AAL63926.1 - 2.6e-23 82.2 1.0 7.9e-12 45.4 0.1 2.1 2 0 0 2 2 2 2 CBS domain QueC PF06508.13 AAL63927.1 - 2.6e-38 131.6 0.0 3.6e-38 131.2 0.0 1.2 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC ThiI PF02568.14 AAL63927.1 - 0.00016 21.4 0.0 0.00023 20.8 0.0 1.2 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) CN_hydrolase PF00795.22 AAL63928.1 - 1.7e-35 122.7 0.0 2e-35 122.4 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase AIRS PF00586.24 AAL63928.1 - 0.026 15.2 0.0 0.062 14.0 0.0 1.6 1 0 0 1 1 1 0 AIR synthase related protein, N-terminal domain LysE PF01810.18 AAL63929.1 - 1e-24 87.1 14.1 1.3e-24 86.7 14.1 1.1 1 0 0 1 1 1 1 LysE type translocator Phtf-FEM1B_bdg PF12129.8 AAL63929.1 - 0.096 12.5 0.9 0.17 11.7 0.9 1.5 1 0 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor MaoC_dehydratas PF01575.19 AAL63929.1 - 0.16 11.5 0.1 0.25 10.9 0.1 1.3 1 0 0 1 1 1 0 MaoC like domain Ycf4 PF02392.16 AAL63929.1 - 2.9 7.4 5.3 0.92 9.1 0.7 2.0 2 0 0 2 2 2 0 Ycf4 DUF72 PF01904.18 AAL63930.1 - 1.4e-45 156.1 0.3 1.7e-45 155.8 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF72 DUF4148 PF13663.6 AAL63931.1 - 0.36 11.1 3.1 0.74 10.0 3.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) ABC_tran PF00005.27 AAL63932.1 - 7.1e-30 104.3 0.0 9.3e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAL63932.1 - 2.6e-16 60.3 0.3 3.8e-07 30.2 0.2 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAL63932.1 - 1.2e-08 34.6 0.1 0.00036 20.0 0.0 2.0 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAL63932.1 - 1.8e-05 24.3 0.0 3.7e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AAL63932.1 - 2.8e-05 24.7 0.4 6.8e-05 23.5 0.0 1.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AAL63932.1 - 0.0001 22.7 0.0 0.00015 22.2 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.6 AAL63932.1 - 0.00016 21.5 0.0 0.0011 18.7 0.0 1.9 1 1 0 2 2 2 1 AAA ATPase domain AAA_27 PF13514.6 AAL63932.1 - 0.00088 18.9 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 AAL63932.1 - 0.0061 15.4 0.2 0.045 12.5 0.1 2.0 2 0 0 2 2 2 1 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 AAL63932.1 - 0.0087 16.0 0.1 0.087 12.7 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 AAL63932.1 - 0.012 15.9 0.0 0.029 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AAL63932.1 - 0.014 15.1 0.1 0.03 14.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AAL63932.1 - 0.017 15.3 0.1 0.056 13.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 AAL63932.1 - 0.019 14.8 0.2 0.14 12.0 0.1 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA PF00004.29 AAL63932.1 - 0.024 15.1 0.0 0.042 14.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 AAL63932.1 - 0.028 14.3 0.2 0.056 13.4 0.2 1.8 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 AAL63932.1 - 0.038 14.0 0.1 1.1 9.3 0.0 2.3 1 1 0 2 2 2 0 AAA domain NACHT PF05729.12 AAL63932.1 - 0.071 13.0 0.1 0.15 12.0 0.1 1.5 2 0 0 2 2 1 0 NACHT domain Dynamin_N PF00350.23 AAL63932.1 - 0.13 12.3 0.4 0.24 11.4 0.4 1.4 1 0 0 1 1 1 0 Dynamin family NTPase_1 PF03266.15 AAL63932.1 - 0.14 12.0 0.0 0.38 10.7 0.0 1.7 2 0 0 2 2 2 0 NTPase Herpes_UL31 PF02718.14 AAL63932.1 - 0.18 10.8 0.0 0.33 9.9 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL31-like protein MMR_HSR1 PF01926.23 AAL63932.1 - 0.19 11.8 0.4 0.5 10.5 0.3 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase cobW PF02492.19 AAL63932.1 - 0.2 11.2 0.1 0.36 10.4 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 AAL63932.1 - 0.29 11.4 0.5 1.1 9.5 0.2 2.0 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 AAL63933.1 - 2.8e-26 92.7 0.0 3.5e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAL63933.1 - 1.6e-11 44.6 1.7 0.00012 22.0 0.1 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AAL63933.1 - 7.9e-06 25.5 0.1 1.4e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AAL63933.1 - 4.8e-05 23.8 0.1 7.1e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 AAL63933.1 - 0.00011 22.7 0.2 0.00017 22.2 0.2 1.2 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 AAL63933.1 - 0.00014 21.4 0.1 0.026 14.0 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 AAL63933.1 - 0.00015 21.6 0.0 0.073 12.8 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 AAL63933.1 - 0.0012 18.6 0.1 0.0027 17.4 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AAL63933.1 - 0.0016 18.7 0.1 0.01 16.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain BCA_ABC_TP_C PF12399.8 AAL63933.1 - 0.0023 17.8 0.0 0.0038 17.1 0.0 1.4 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter T2SSE PF00437.20 AAL63933.1 - 0.004 16.2 0.2 0.0063 15.6 0.2 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_25 PF13481.6 AAL63933.1 - 0.012 15.2 0.2 0.1 12.1 0.1 2.2 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 AAL63933.1 - 0.024 14.6 0.0 0.052 13.5 0.0 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 AAL63933.1 - 0.033 13.8 0.3 0.055 13.0 0.3 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 AAL63933.1 - 0.034 14.6 0.0 0.071 13.5 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 AAL63933.1 - 0.044 13.7 0.0 0.074 12.9 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase ATPase_2 PF01637.18 AAL63933.1 - 0.076 12.9 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 AAL63933.1 - 0.096 12.0 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin SRP54 PF00448.22 AAL63933.1 - 0.12 12.0 0.1 0.2 11.3 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_19 PF13245.6 AAL63933.1 - 0.15 12.4 0.1 0.34 11.2 0.1 1.5 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 AAL63933.1 - 0.18 11.1 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MobB PF03205.14 AAL63933.1 - 0.21 11.5 0.1 0.41 10.6 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DnaB_C PF03796.15 AAL63933.1 - 0.26 10.6 0.0 5.1 6.4 0.1 2.0 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain ANF_receptor PF01094.28 AAL63934.1 - 5.4e-45 154.0 0.4 7e-45 153.7 0.4 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 AAL63934.1 - 2e-31 109.9 12.0 2.8e-31 109.4 12.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein SKG6 PF08693.10 AAL63934.1 - 0.52 9.8 4.6 1.5 8.3 4.6 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain BPD_transp_2 PF02653.16 AAL63935.1 - 2.6e-35 121.9 33.1 3.7e-35 121.4 33.1 1.2 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component BPD_transp_2 PF02653.16 AAL63936.1 - 6.7e-41 140.2 31.2 6.7e-41 140.2 31.2 1.5 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component AhpC-TSA PF00578.21 AAL63937.1 - 5.3e-29 100.7 0.0 6.8e-29 100.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 AAL63937.1 - 6.6e-14 51.5 0.8 1.2e-13 50.7 0.8 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 AAL63937.1 - 6.4e-13 48.6 0.0 7.2e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin adh_short_C2 PF13561.6 AAL63939.1 - 3.7e-60 203.4 0.6 4.6e-60 203.1 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAL63939.1 - 9.1e-49 165.6 0.1 1.2e-48 165.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAL63939.1 - 2.2e-13 50.5 0.2 4.2e-13 49.6 0.2 1.4 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 AAL63939.1 - 8.9e-06 25.3 0.1 2.6e-05 23.8 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 AAL63939.1 - 0.00054 19.9 1.1 0.00098 19.1 1.1 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Robl_LC7 PF03259.17 AAL63939.1 - 0.0095 15.7 0.5 0.5 10.2 0.0 2.9 3 0 0 3 3 3 1 Roadblock/LC7 domain NmrA PF05368.13 AAL63939.1 - 0.094 12.3 1.1 0.14 11.7 0.5 1.5 2 0 0 2 2 2 0 NmrA-like family Glyco_transf_28 PF03033.20 AAL63939.1 - 0.11 12.5 0.1 0.35 10.9 0.1 1.9 2 0 0 2 2 2 0 Glycosyltransferase family 28 N-terminal domain GIDA PF01134.22 AAL63939.1 - 0.16 11.0 0.2 0.21 10.6 0.2 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF429 PF04250.13 AAL63940.1 - 3.6e-12 46.5 0.4 3.5e-06 27.0 0.0 3.0 1 1 1 2 2 2 2 Protein of unknown function (DUF429) DAO PF01266.24 AAL63941.1 - 1.2e-36 127.0 2.7 1.6e-36 126.6 2.7 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 AAL63941.1 - 1.1e-06 28.1 3.5 0.015 14.6 0.1 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AAL63941.1 - 4.1e-06 26.9 0.1 8.8e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 AAL63941.1 - 5.2e-05 22.5 0.6 0.00016 20.9 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 AAL63941.1 - 0.00049 19.4 0.3 0.00078 18.8 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 AAL63941.1 - 0.0019 17.4 0.2 0.63 9.1 0.3 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Lycopene_cycl PF05834.12 AAL63941.1 - 0.0026 16.9 0.4 0.56 9.2 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.14 AAL63941.1 - 0.0039 15.9 0.9 0.008 14.9 0.5 1.6 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 AAL63941.1 - 0.0062 15.8 0.1 0.019 14.3 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAL63941.1 - 0.015 15.8 2.4 0.03 14.9 0.6 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 AAL63941.1 - 0.054 13.1 0.1 0.094 12.4 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.7 AAL63941.1 - 0.07 12.5 0.2 0.13 11.6 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase CoA_transf_3 PF02515.17 AAL63941.1 - 0.095 11.8 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 CoA-transferase family III NAD_binding_7 PF13241.6 AAL63941.1 - 0.17 12.3 0.0 0.34 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 AAL63941.1 - 0.31 10.6 0.5 0.49 9.9 0.5 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 AAL63941.1 - 6.3 6.0 5.0 0.71 9.1 0.5 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain SBP_bac_3 PF00497.20 AAL63942.1 - 3.7e-56 190.1 0.1 4.6e-56 189.8 0.1 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 AAL63942.1 - 6.3e-08 32.8 0.0 2.9e-07 30.7 0.0 2.0 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site NMT1 PF09084.11 AAL63942.1 - 0.00062 19.8 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.7 AAL63942.1 - 0.0014 18.3 0.3 0.015 14.9 0.3 2.4 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein DctP PF03480.13 AAL63942.1 - 0.021 14.2 0.0 0.078 12.3 0.0 1.8 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein, family 7 CPP1-like PF11833.8 AAL63942.1 - 0.04 13.6 0.1 0.067 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like LysR_substrate PF03466.20 AAL63942.1 - 0.072 12.4 0.1 0.34 10.2 0.0 2.0 2 0 0 2 2 2 0 LysR substrate binding domain EpuA PF11772.8 AAL63942.1 - 0.61 9.8 5.1 1.2 8.9 5.1 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta Ribosomal_S14 PF00253.21 AAL63943.1 - 1.5e-11 43.9 3.5 1.8e-11 43.6 3.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e zf-FPG_IleRS PF06827.14 AAL63943.1 - 0.0053 16.6 4.8 0.007 16.2 4.8 1.2 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS zf-CCHC_2 PF13696.6 AAL63943.1 - 1.2 9.1 5.9 1.1 9.2 0.8 2.2 2 0 0 2 2 2 0 Zinc knuckle Ribosomal_L37e PF01907.19 AAL63943.1 - 5.1 7.3 8.5 1.4 9.1 0.7 2.2 1 1 1 2 2 2 0 Ribosomal protein L37e Ribosomal_S8 PF00410.19 AAL63944.1 - 5e-22 78.2 0.7 1.4e-21 76.8 0.7 1.6 1 1 0 1 1 1 1 Ribosomal protein S8 Ribosomal_L32e PF01655.18 AAL63945.1 - 4.8e-37 126.7 0.3 6e-37 126.4 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Ribosomal_L19e PF01280.20 AAL63946.1 - 1.5e-45 154.8 5.9 1.7e-45 154.7 5.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L19e DUF4188 PF13826.6 AAL63946.1 - 0.08 13.3 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4188) B56 PF01603.20 AAL63946.1 - 0.11 11.5 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Ribosomal_L5e PF17144.4 AAL63947.1 - 2.5e-31 108.9 2.6 3.8e-19 69.3 0.6 2.6 2 1 1 3 3 3 2 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 AAL63947.1 - 2.5e-14 54.0 1.9 4.5e-14 53.2 1.9 1.4 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region Ribosomal_L18p PF00861.22 AAL63947.1 - 9.8e-09 35.6 0.2 1.6e-08 34.9 0.2 1.4 1 0 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast DUF4231 PF14015.6 AAL63948.1 - 2.9 8.4 7.9 0.3 11.6 2.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) PaRep2b PF07775.11 AAL63949.1 - 1.4e-27 96.4 0.1 1.6e-27 96.2 0.1 1.0 1 0 0 1 1 1 1 PaRep2b protein Big_1 PF02369.16 AAL63949.1 - 0.062 13.3 0.0 0.091 12.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) WXG100 PF06013.12 AAL63949.1 - 0.12 12.7 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 Proteins of 100 residues with WXG PaRep2a PF07903.11 AAL63951.1 - 7.1e-42 142.1 0.3 7.6e-42 142.0 0.3 1.0 1 0 0 1 1 1 1 PaRep2a protein DNA_pol_B PF00136.21 AAL63952.1 - 8.6e-70 235.7 0.0 1.2e-69 235.3 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 AAL63952.1 - 9.8e-36 123.6 0.0 1.7e-19 70.1 0.0 2.3 1 1 1 2 2 2 2 DNA polymerase family B, exonuclease domain DNA_pol_B_exo2 PF10108.9 AAL63952.1 - 6.3e-08 32.5 0.0 1.1e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 AAL63952.1 - 8.2e-06 25.9 0.0 1.8e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 RNase_H superfamily Bac_luciferase PF00296.20 AAL63952.1 - 0.12 11.7 0.1 0.24 10.8 0.1 1.4 1 0 0 1 1 1 0 Luciferase-like monooxygenase Glyco_transf_4 PF13439.6 AAL63952.1 - 0.23 11.4 1.8 13 5.7 0.0 3.4 3 0 0 3 3 3 0 Glycosyltransferase Family 4 Toprim_4 PF13662.6 AAL63955.1 - 4.4e-08 33.5 0.2 1.5e-07 31.8 0.2 2.0 1 0 0 1 1 1 1 Toprim domain Toprim_2 PF13155.6 AAL63955.1 - 7.7e-05 23.0 0.0 0.00024 21.4 0.0 1.9 1 0 0 1 1 1 1 Toprim-like Toprim PF01751.22 AAL63955.1 - 0.00016 21.8 1.4 0.0011 19.2 0.1 2.5 2 0 0 2 2 2 1 Toprim domain PBSX_XtrA PF17356.2 AAL63955.1 - 0.048 13.5 1.2 0.11 12.4 0.2 2.2 2 0 0 2 2 2 0 Phage-like element PBSX protein XtrA Peptidase_M24 PF00557.24 AAL63956.1 - 1.4e-36 126.2 0.0 1.6e-36 126.0 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 Cpn60_TCP1 PF00118.24 AAL63957.1 - 2.6e-179 597.0 9.4 2.9e-179 596.8 9.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Dak2 PF02734.17 AAL63957.1 - 9.2e-06 25.7 0.8 0.003 17.5 0.8 2.5 2 0 0 2 2 2 2 DAK2 domain DUF2710 PF10921.8 AAL63957.1 - 0.023 15.1 0.2 1.4 9.3 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2710) T2SSE PF00437.20 AAL63959.1 - 2.2e-23 82.7 0.1 2.9e-23 82.3 0.1 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 AAL63959.1 - 2.3e-06 28.2 0.0 4e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 AAL63959.1 - 2.2e-05 24.9 0.0 4.1e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 AAL63959.1 - 2.8e-05 23.9 0.0 6.3e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AAL63959.1 - 2.8e-05 24.7 0.0 5.5e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 AAL63959.1 - 6.8e-05 22.8 2.8 0.0031 17.4 0.1 2.9 2 1 0 3 3 3 1 NTPase AAA_22 PF13401.6 AAL63959.1 - 0.0002 21.6 2.3 0.0051 17.1 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 AAL63959.1 - 0.00034 20.6 0.1 0.00057 19.9 0.1 1.4 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 AAL63959.1 - 0.00076 19.5 0.2 0.0017 18.3 0.1 1.7 2 0 0 2 2 1 1 ATPase domain predominantly from Archaea RNA12 PF10443.9 AAL63959.1 - 0.0019 17.0 0.0 0.0029 16.4 0.0 1.3 1 0 0 1 1 1 1 RNA12 protein AAA_23 PF13476.6 AAL63959.1 - 0.0037 17.8 0.0 0.0071 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 AAL63959.1 - 0.0042 16.5 0.0 0.0073 15.7 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI cobW PF02492.19 AAL63959.1 - 0.0043 16.7 0.0 0.0075 15.9 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 AAL63959.1 - 0.0058 16.3 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_28 PF13521.6 AAL63959.1 - 0.0064 16.8 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 AAL63959.1 - 0.007 16.1 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 AAL63959.1 - 0.0083 15.9 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 AAL63959.1 - 0.011 16.1 0.0 0.026 14.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 AAL63959.1 - 0.011 15.4 0.0 0.024 14.4 0.0 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_21 PF13304.6 AAL63959.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 AAL63959.1 - 0.012 15.5 0.2 0.036 14.0 0.0 1.9 1 1 1 2 2 2 0 NACHT domain AAA_24 PF13479.6 AAL63959.1 - 0.014 15.1 0.1 0.026 14.2 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AAL63959.1 - 0.016 14.8 0.1 0.031 13.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain dNK PF01712.19 AAL63959.1 - 0.017 15.0 1.9 1.2 8.9 0.1 2.7 2 1 1 3 3 3 0 Deoxynucleoside kinase RsgA_GTPase PF03193.16 AAL63959.1 - 0.021 14.8 0.0 0.05 13.5 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase KTI12 PF08433.10 AAL63959.1 - 0.021 14.3 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DEAD PF00270.29 AAL63959.1 - 0.035 13.9 2.3 1.5 8.6 0.0 3.1 2 1 1 3 3 3 0 DEAD/DEAH box helicase TrwB_AAD_bind PF10412.9 AAL63959.1 - 0.038 12.9 0.0 0.063 12.2 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_5 PF07728.14 AAL63959.1 - 0.042 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 AAL63959.1 - 0.05 12.9 0.0 0.17 11.1 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin Rad17 PF03215.15 AAL63959.1 - 0.054 13.4 0.0 0.14 12.1 0.0 1.7 1 1 0 1 1 1 0 Rad17 P-loop domain DUF2075 PF09848.9 AAL63959.1 - 0.096 11.9 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.18 AAL63959.1 - 0.096 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA PF00004.29 AAL63959.1 - 0.13 12.7 4.4 2.5 8.5 4.4 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 AAL63959.1 - 0.16 11.7 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 AAL63959.1 - 0.22 11.7 0.5 0.48 10.6 0.5 1.8 1 1 0 1 1 1 0 AAA domain TF_Zn_Ribbon PF08271.12 AAL63960.1 - 2.1e-07 30.3 1.3 3.4e-07 29.7 1.3 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding TFIIB PF00382.19 AAL63960.1 - 9.5e-07 28.8 0.1 1.6e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 Transcription factor TFIIB repeat zf-RRN7 PF11781.8 AAL63960.1 - 0.00017 21.2 0.4 0.00023 20.8 0.4 1.2 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 A2L_zn_ribbon PF08792.10 AAL63960.1 - 0.0019 17.8 1.4 0.0029 17.3 1.4 1.3 1 0 0 1 1 1 1 A2L zinc ribbon domain Cyclin_C PF02984.19 AAL63960.1 - 0.0049 17.0 0.1 0.043 13.9 0.0 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain HTH_23 PF13384.6 AAL63960.1 - 0.014 15.2 1.0 24 4.9 0.1 3.7 1 1 2 3 3 3 0 Homeodomain-like domain OrfB_Zn_ribbon PF07282.11 AAL63960.1 - 0.021 14.7 0.3 0.049 13.6 0.3 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.6 AAL63960.1 - 0.035 13.5 2.5 0.11 12.0 2.5 1.8 1 1 0 1 1 1 0 zinc-ribbon domain HTH_22 PF13309.6 AAL63960.1 - 0.063 13.4 0.1 11 6.2 0.0 2.7 2 0 0 2 2 2 0 HTH domain Fe_dep_repress PF01325.19 AAL63960.1 - 0.064 13.5 0.0 5.4 7.3 0.0 2.3 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain RPA_interact_C PF14768.6 AAL63960.1 - 0.072 13.7 0.1 0.1 13.2 0.1 1.4 1 0 0 1 1 1 0 Replication protein A interacting C-terminal zf-ISL3 PF14690.6 AAL63960.1 - 0.09 13.5 0.6 16 6.3 0.1 2.5 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Phage_terminase PF10668.9 AAL63960.1 - 0.15 12.1 0.0 18 5.5 0.0 2.5 2 1 0 2 2 2 0 Phage terminase small subunit zf-RRPl_C4 PF17026.5 AAL63960.1 - 0.34 11.0 1.5 0.56 10.3 1.5 1.6 1 1 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type Rubredoxin_2 PF18073.1 AAL63960.1 - 0.36 10.6 2.8 5.7 6.7 0.2 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain RNA_pol_RpbG PF16992.5 AAL63961.1 - 0.00061 19.8 0.1 0.00068 19.7 0.1 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase, subunit G Lsm_C PF14894.6 AAL63962.1 - 3.2e-23 81.3 1.2 7.2e-23 80.1 1.2 1.5 1 0 0 1 1 1 1 Lsm C-terminal SM-ATX PF14438.6 AAL63962.1 - 4e-12 46.1 0.1 8.3e-12 45.1 0.1 1.6 1 1 0 1 1 1 1 Ataxin 2 SM domain LSM PF01423.22 AAL63962.1 - 1.4e-10 40.7 1.0 2.2e-10 40.1 1.1 1.6 1 1 0 1 1 1 1 LSM domain LSM14 PF12701.7 AAL63962.1 - 0.0041 17.2 0.1 0.012 15.7 0.1 1.9 1 1 0 1 1 1 1 Scd6-like Sm domain Gemin6 PF06372.12 AAL63962.1 - 0.065 12.8 0.1 0.1 12.1 0.1 1.4 1 1 0 1 1 1 0 Gemin6 protein PaRep2a PF07903.11 AAL63963.1 - 2.5e-62 208.1 0.9 5e-62 207.1 0.9 1.5 1 0 0 1 1 1 1 PaRep2a protein PaRep2a PF07903.11 AAL63964.1 - 9.1e-64 212.8 1.9 1e-63 212.6 1.9 1.0 1 0 0 1 1 1 1 PaRep2a protein PaRep2b PF07775.11 AAL63966.1 - 1.7e-271 901.2 15.2 2.2e-271 900.7 15.2 1.1 1 0 0 1 1 1 1 PaRep2b protein SusF_SusE PF16411.5 AAL63966.1 - 1.2 9.7 3.2 12 6.4 0.1 3.0 1 1 2 3 3 3 0 Outer membrane protein SusF_SusE DEAD PF00270.29 AAL63967.1 - 6.3e-30 104.2 0.0 2.7e-29 102.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AAL63967.1 - 9.5e-20 71.0 0.0 2.2e-17 63.4 0.1 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD_assoc PF08494.11 AAL63967.1 - 5.1e-14 52.5 0.0 2.9e-13 50.0 0.0 2.2 1 1 0 1 1 1 1 DEAD/H associated ResIII PF04851.15 AAL63967.1 - 1.2e-06 28.6 0.0 3e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HypA PF01155.19 AAL63967.1 - 0.0019 18.2 0.0 0.0045 17.0 0.0 1.5 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA HHH_5 PF14520.6 AAL63967.1 - 0.01 16.4 0.2 1.2 9.8 0.0 3.3 3 0 0 3 3 3 0 Helix-hairpin-helix domain AAA_22 PF13401.6 AAL63967.1 - 0.038 14.3 0.0 0.15 12.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain Fumerase_C PF05683.12 AAL63968.1 - 5.9e-51 172.7 0.4 7e-51 172.5 0.4 1.0 1 0 0 1 1 1 1 Fumarase C-terminus CDC24_OB3 PF17244.2 AAL63968.1 - 0.051 13.3 0.0 0.077 12.7 0.0 1.2 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 3 Fumerase PF05681.14 AAL63969.1 - 7.4e-81 271.5 0.0 8.3e-81 271.3 0.0 1.0 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) H-K_ATPase_N PF09040.11 AAL63969.1 - 0.15 12.5 0.0 0.47 10.9 0.0 1.8 1 0 0 1 1 1 0 Gastric H+/K+-ATPase, N terminal domain RHH_1 PF01402.21 AAL63970.1 - 0.0001 22.1 0.0 0.00012 21.9 0.0 1.1 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family RHH_8 PF17723.1 AAL63970.1 - 0.00047 20.3 0.0 0.00047 20.3 0.0 1.1 1 0 0 1 1 1 1 Ribbon-Helix-Helix transcriptional regulator family MtlR PF05068.12 AAL63970.1 - 0.0096 16.0 0.0 0.0096 16.0 0.0 1.0 1 0 0 1 1 1 1 Mannitol repressor LINES_C PF14695.6 AAL63970.1 - 0.097 12.1 0.2 0.28 10.7 0.0 1.8 2 0 0 2 2 2 0 Lines C-terminus Flavin_Reduct PF01613.18 AAL63971.1 - 2.6e-07 30.8 0.0 3.9e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain ThiS PF02597.20 AAL63972.1 - 1.7e-21 76.6 0.0 1.9e-21 76.5 0.0 1.0 1 0 0 1 1 1 1 ThiS family Urm1 PF09138.11 AAL63972.1 - 4.7e-08 33.3 0.0 5.2e-08 33.1 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS-like PF14453.6 AAL63972.1 - 0.0021 18.0 0.3 0.033 14.2 0.3 2.9 1 1 2 3 3 3 1 ThiS-like ubiquitin NLE PF08154.12 AAL63972.1 - 0.003 18.0 0.1 0.0055 17.2 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain YukD PF08817.10 AAL63972.1 - 0.046 14.4 0.0 0.054 14.2 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD PaRep2a PF07903.11 AAL63973.1 - 0.0077 16.1 0.1 0.0083 16.0 0.1 1.1 1 0 0 1 1 1 1 PaRep2a protein PTPS PF01242.19 AAL63974.1 - 2.6e-07 30.6 0.0 3.2e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase NepR PF18557.1 AAL63974.1 - 0.042 13.5 0.5 0.071 12.8 0.5 1.3 1 0 0 1 1 1 0 Anti-sigma factor NepR AGOG PF09171.10 AAL63975.1 - 0.00011 21.6 0.0 0.00017 21.0 0.0 1.2 1 0 0 1 1 1 1 N-glycosylase/DNA lyase zf-C2HC_2 PF13913.6 AAL63976.1 - 0.07 13.0 1.1 0.25 11.3 0.1 2.1 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Baculo_ODV-E27 PF05314.11 AAL63976.1 - 0.13 11.4 0.0 0.16 11.1 0.0 1.0 1 0 0 1 1 1 0 Baculovirus occlusion-derived virus envelope protein EC27 LpxD PF04613.14 AAL63976.1 - 0.19 11.5 0.0 0.28 11.0 0.0 1.2 1 0 0 1 1 1 0 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD Radical_SAM PF04055.21 AAL63981.1 - 1.1e-13 51.8 0.0 1.8e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 AAL63981.1 - 0.0095 16.2 0.0 0.014 15.7 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AAL63981.1 - 0.03 14.4 0.0 0.045 13.9 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S single cluster domain SPASM PF13186.6 AAL63981.1 - 0.067 13.7 0.2 0.15 12.6 0.2 1.6 1 0 0 1 1 1 0 Iron-sulfur cluster-binding domain DUF711 PF05167.12 AAL63984.1 - 7.4e-31 107.5 0.0 2e-30 106.0 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised ACR (DUF711) ASCH PF04266.14 AAL63985.1 - 5e-14 52.8 0.0 7.7e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 ASCH domain Radical_SAM PF04055.21 AAL63986.1 - 1.9e-05 25.1 0.0 7.5e-05 23.2 0.0 2.1 1 1 0 1 1 1 1 Radical SAM superfamily Urease_linker PF18473.1 AAL63986.1 - 0.014 15.3 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Urease subunit beta-alpha linker domain UPF0180 PF03698.13 AAL63986.1 - 0.21 11.8 0.0 0.71 10.1 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0180) NurA PF09376.10 AAL63987.1 - 5.4e-44 150.7 0.1 1.6e-43 149.1 0.1 1.7 1 1 0 1 1 1 1 NurA domain DUF87 PF01935.17 AAL63988.1 - 2.7e-26 93.1 0.1 4.5e-26 92.4 0.1 1.4 1 0 0 1 1 1 1 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 AAL63988.1 - 1.2e-09 37.6 0.0 7.9e-08 31.6 0.0 2.1 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_10 PF12846.7 AAL63988.1 - 5.4e-06 25.6 0.0 0.0092 14.9 0.0 2.2 2 0 0 2 2 2 2 AAA-like domain AAA_16 PF13191.6 AAL63988.1 - 7.1e-06 26.5 0.0 8.9e-05 22.9 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AAL63988.1 - 5.3e-05 23.5 0.1 0.021 15.1 0.1 2.3 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 AAL63988.1 - 9.4e-05 21.7 0.0 0.00018 20.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.18 AAL63988.1 - 0.00011 21.7 0.0 0.005 16.2 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family ATPase_2 PF01637.18 AAL63988.1 - 0.00037 20.5 3.1 0.0065 16.4 3.1 2.2 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea MeaB PF03308.16 AAL63988.1 - 0.00064 18.8 0.1 0.0012 17.9 0.1 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 AAL63988.1 - 0.0011 19.0 0.0 0.0052 16.9 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase CLP1_P PF16575.5 AAL63988.1 - 0.0022 17.8 0.1 0.017 14.9 0.0 2.2 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Zot PF05707.12 AAL63988.1 - 0.0032 17.1 0.0 0.0061 16.2 0.0 1.4 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) PhoH PF02562.16 AAL63988.1 - 0.0046 16.4 0.5 0.083 12.3 0.0 2.6 2 1 1 3 3 3 1 PhoH-like protein AAA PF00004.29 AAL63988.1 - 0.0082 16.6 0.4 0.57 10.6 0.3 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MobB PF03205.14 AAL63988.1 - 0.01 15.7 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.23 AAL63988.1 - 0.01 15.9 0.0 0.019 15.0 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_14 PF13173.6 AAL63988.1 - 0.014 15.4 0.1 5.6 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 AAL63988.1 - 0.025 15.1 0.0 0.05 14.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_30 PF13604.6 AAL63988.1 - 0.031 14.0 0.4 0.69 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 AAL63988.1 - 0.063 12.8 0.0 0.15 11.6 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 AAL63988.1 - 0.068 12.9 0.1 0.21 11.3 0.1 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_19 PF13245.6 AAL63988.1 - 0.074 13.4 0.5 13 6.1 0.1 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 AAL63988.1 - 0.079 13.4 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 AAL63988.1 - 0.084 12.8 0.5 0.21 11.5 0.1 1.9 2 0 0 2 2 2 0 NTPase AAA_18 PF13238.6 AAL63988.1 - 0.1 13.2 0.1 0.22 12.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain DUF853 PF05872.12 AAL63988.1 - 0.14 10.7 0.0 1.1 7.7 0.0 2.2 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF853) RsgA_GTPase PF03193.16 AAL63988.1 - 0.15 11.9 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase CTP-dep_RFKase PF01982.16 AAL63989.1 - 2.2e-47 160.1 0.0 2.9e-47 159.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF120 HTH_29 PF13551.6 AAL63989.1 - 0.00011 22.2 0.0 0.00018 21.5 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 AAL63989.1 - 0.0017 18.4 0.0 0.0034 17.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AAL63989.1 - 0.0019 17.9 0.0 0.0037 17.0 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain MarR_2 PF12802.7 AAL63989.1 - 0.015 15.2 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_Crp_2 PF13545.6 AAL63989.1 - 0.016 15.2 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain MazE_antitoxin PF04014.18 AAL63989.1 - 0.024 14.6 0.5 0.27 11.2 0.1 2.6 2 0 0 2 2 2 0 Antidote-toxin recognition MazE, bacterial antitoxin HTH_34 PF13601.6 AAL63989.1 - 0.053 13.7 0.0 8.3 6.7 0.0 3.2 2 1 0 2 2 2 0 Winged helix DNA-binding domain Sigma70_r4_2 PF08281.12 AAL63989.1 - 0.087 12.5 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 Rrf2 PF02082.20 AAL63989.1 - 0.13 12.6 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator HTH_Tnp_1 PF01527.20 AAL63989.1 - 0.15 12.4 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 Transposase Aldolase_II PF00596.21 AAL63990.1 - 1.3e-41 142.6 0.0 1.5e-41 142.4 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Peptidase_C92 PF05708.12 AAL63990.1 - 0.027 14.6 0.0 0.034 14.2 0.0 1.3 1 0 0 1 1 1 0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family Peptidase_M19 PF01244.21 AAL63990.1 - 0.094 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) Trp_halogenase PF04820.14 AAL63991.1 - 3.7e-11 42.5 0.6 0.014 14.3 0.0 3.1 2 1 1 3 3 3 3 Tryptophan halogenase FAD_oxidored PF12831.7 AAL63991.1 - 3e-07 30.2 4.0 8.3e-07 28.7 4.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 AAL63991.1 - 3.4e-07 30.2 4.6 0.0019 17.9 0.1 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AAL63991.1 - 5.4e-07 29.0 5.8 0.00062 19.0 2.6 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 AAL63991.1 - 7.5e-06 25.4 0.9 2.8e-05 23.5 0.2 2.0 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 AAL63991.1 - 1.2e-05 24.7 0.5 2e-05 23.8 0.5 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 AAL63991.1 - 5.9e-05 22.5 2.7 0.00079 18.8 0.4 3.0 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.6 AAL63991.1 - 0.0002 21.5 0.9 0.00059 20.0 0.9 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 AAL63991.1 - 0.00038 19.3 0.1 0.00052 18.8 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 AAL63991.1 - 0.00093 18.5 0.2 0.0013 18.0 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 AAL63991.1 - 0.0077 15.3 1.7 2.8 6.9 2.7 2.8 2 1 0 2 2 2 1 Lycopene cyclase protein 3HCDH_N PF02737.18 AAL63991.1 - 0.11 12.4 0.4 0.19 11.6 0.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lactamase_B_3 PF13483.6 AAL63992.1 - 1.6e-26 93.2 0.0 1.9e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 AAL63992.1 - 8.7e-26 90.7 0.6 1e-25 90.4 0.6 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 AAL63992.1 - 2.5e-11 44.0 1.9 8.7e-11 42.2 1.9 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Hjc PF01870.18 AAL63994.1 - 6.1e-31 106.3 0.1 8.1e-31 105.9 0.1 1.2 1 0 0 1 1 1 1 Archaeal holliday junction resolvase (hjc) AHJR-like PF18743.1 AAL63994.1 - 0.00037 20.0 0.0 0.0005 19.6 0.0 1.2 1 0 0 1 1 1 1 REase_AHJR-like NERD PF08378.11 AAL63994.1 - 0.008 16.6 0.0 0.0097 16.4 0.0 1.4 1 1 0 1 1 1 1 Nuclease-related domain TBP PF00352.21 AAL63996.1 - 1.9e-63 210.4 0.1 8e-31 105.8 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 AAL63996.1 - 0.00029 20.9 0.0 0.0081 16.3 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3378) Cobl PF09469.10 AAL63996.1 - 0.074 13.3 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Cordon-bleu ubiquitin-like domain tRNA-synt_2b PF00587.25 AAL63997.1 - 2.2e-26 92.9 0.0 3.8e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 AAL63997.1 - 4.1e-22 78.1 0.1 8.8e-22 77.1 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain ProRS-C_1 PF09180.11 AAL63997.1 - 8.1e-09 35.6 0.0 2.1e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal Imm30 PF15565.6 AAL63997.1 - 0.03 14.4 0.2 0.18 11.9 0.0 2.2 2 0 0 2 2 2 0 Immunity protein 30 GCD14 PF08704.10 AAL63998.1 - 6e-33 114.5 0.0 7.9e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 AAL63998.1 - 6.3e-07 29.4 0.1 1.3e-06 28.4 0.1 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 AAL63998.1 - 1.5e-06 28.1 0.0 2.2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAL63998.1 - 4.5e-05 24.1 0.0 0.00012 22.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAL63998.1 - 0.00012 22.7 0.0 0.00037 21.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_24 PF13578.6 AAL63998.1 - 0.00018 22.5 0.0 0.00062 20.8 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain GCD14_N PF14801.6 AAL63998.1 - 0.0013 18.6 0.0 0.0029 17.4 0.0 1.7 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term Ubie_methyltran PF01209.18 AAL63998.1 - 0.063 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family ADH_zinc_N PF00107.26 AAL63998.1 - 0.073 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase CMAS PF02353.20 AAL63998.1 - 0.098 11.9 0.0 0.18 11.0 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 AAL63998.1 - 0.15 12.2 0.0 1.5 8.9 0.0 1.8 1 1 1 2 2 2 0 FtsJ-like methyltransferase Ribosomal_S26e PF01283.19 AAL64000.1 - 4.6e-26 91.4 2.5 5.1e-26 91.2 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e DUF5637 PF18687.1 AAL64000.1 - 0.031 14.2 1.7 0.065 13.2 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5637) Auto_anti-p27 PF06677.12 AAL64000.1 - 0.044 13.9 0.2 13 6.1 0.1 2.3 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zinc_ribbon_15 PF17032.5 AAL64000.1 - 0.046 14.5 0.2 0.18 12.6 0.1 1.8 1 1 0 1 1 1 0 zinc-ribbon family zf-dskA_traR PF01258.17 AAL64000.1 - 0.071 13.1 0.6 7.1 6.7 0.2 2.4 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger PaRep2b PF07775.11 AAL64002.1 - 6.9e-14 51.2 0.3 8.5e-13 47.6 0.0 2.3 2 1 0 2 2 2 1 PaRep2b protein Methyltrn_RNA_2 PF04013.12 AAL64003.1 - 2.1e-08 34.1 0.0 2.6e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Putative SAM-dependent RNA methyltransferase DUF4213 PF13938.6 AAL64003.1 - 0.026 14.7 0.0 0.05 13.8 0.0 1.4 1 0 0 1 1 1 0 Putative heavy-metal chelation Lipocalin PF00061.23 AAL64003.1 - 0.11 12.7 0.0 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family CDP-OH_P_transf PF01066.21 AAL64004.1 - 1.2e-08 35.6 0.9 1.2e-08 35.6 0.9 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF2286 PF10051.9 AAL64005.1 - 1.2e-42 144.9 2.4 1.3e-42 144.8 2.4 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2286) DUF3201 PF11447.8 AAL64005.1 - 0.023 14.2 0.1 0.048 13.2 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3201) DNA_pol_B PF00136.21 AAL64007.1 - 1.1e-48 166.1 0.4 2.5e-48 165.0 0.4 1.6 1 1 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 AAL64007.1 - 1.9e-31 109.5 1.9 1.9e-31 109.5 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B_exo2 PF10108.9 AAL64007.1 - 3.1e-05 23.8 0.0 7.8e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 AAL64007.1 - 0.00091 19.2 0.1 0.0031 17.5 0.1 1.9 1 0 0 1 1 1 1 RNase_H superfamily YscJ_FliF_C PF08345.11 AAL64007.1 - 0.23 11.8 1.1 0.43 10.9 1.1 1.4 1 0 0 1 1 1 0 Flagellar M-ring protein C-terminal HMG-CoA_red PF00368.18 AAL64009.1 - 3.1e-134 447.6 2.5 3.5e-134 447.5 2.5 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Thiolase_N PF00108.23 AAL64010.1 - 1.1e-13 51.2 0.0 4.8e-13 49.1 0.0 2.0 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 AAL64010.1 - 3.1e-07 30.1 0.1 5.8e-07 29.2 0.1 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 AAL64010.1 - 0.0056 16.5 0.2 3.8 7.4 0.0 2.5 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FrhB_FdhB_N PF04422.13 AAL64010.1 - 0.016 15.3 0.1 0.09 12.9 0.0 2.2 1 1 2 3 3 3 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term Ketoacyl-synt_C PF02801.22 AAL64010.1 - 0.034 14.2 0.5 0.31 11.1 0.0 2.6 3 1 1 4 4 4 0 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 AAL64010.1 - 0.072 12.6 0.1 8.2 5.9 0.0 2.6 2 1 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain OB_aCoA_assoc PF01796.17 AAL64011.1 - 6.6e-16 58.1 0.1 9.3e-16 57.6 0.1 1.2 1 0 0 1 1 1 1 DUF35 OB-fold domain, acyl-CoA-associated DUF35_N PF12172.8 AAL64011.1 - 5.8e-10 38.8 2.0 5.8e-10 38.8 2.0 1.5 2 0 0 2 2 2 1 Rubredoxin-like zinc ribbon domain (DUF35_N) ACP_syn_III_C PF08541.10 AAL64012.1 - 5.5e-13 48.9 0.0 4.2e-12 46.1 0.0 2.2 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Thiolase_N PF00108.23 AAL64012.1 - 1.2e-07 31.3 0.1 1.9e-07 30.7 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain HMG_CoA_synt_N PF01154.17 AAL64012.1 - 0.00016 21.6 0.0 0.00022 21.1 0.0 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 AAL64012.1 - 0.00059 19.5 0.0 0.0024 17.6 0.0 1.8 1 1 1 2 2 2 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal FaeA PF04703.12 AAL64013.1 - 2.4e-07 31.0 0.4 2.8e-07 30.8 0.4 1.1 1 0 0 1 1 1 1 FaeA-like protein HTH_9 PF08221.11 AAL64013.1 - 8.2e-06 25.8 0.1 1.1e-05 25.5 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 helix-turn-helix domain HTH_5 PF01022.20 AAL64013.1 - 9.6e-05 22.2 0.2 0.00012 21.9 0.2 1.1 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 AAL64013.1 - 0.00013 21.5 0.3 0.00018 21.0 0.3 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_DeoR PF08220.12 AAL64013.1 - 0.00093 18.9 0.2 0.0021 17.7 0.2 1.7 1 1 0 1 1 1 1 DeoR-like helix-turn-helix domain MarR_2 PF12802.7 AAL64013.1 - 0.0024 17.7 0.0 0.0034 17.2 0.0 1.2 1 0 0 1 1 1 1 MarR family HTH_IclR PF09339.10 AAL64013.1 - 0.0043 16.8 0.0 0.0055 16.5 0.0 1.2 1 0 0 1 1 1 1 IclR helix-turn-helix domain B-block_TFIIIC PF04182.12 AAL64013.1 - 0.0064 16.6 0.1 0.0087 16.2 0.1 1.2 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC TrmB PF01978.19 AAL64013.1 - 0.011 15.7 0.1 0.014 15.2 0.1 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_46 PF15977.5 AAL64013.1 - 0.031 14.3 0.5 0.057 13.4 0.5 1.6 1 1 0 1 1 1 0 Winged helix-turn-helix DNA binding MarR PF01047.22 AAL64013.1 - 0.039 13.9 0.2 0.052 13.5 0.2 1.2 1 0 0 1 1 1 0 MarR family Phage_rep_O PF04492.13 AAL64013.1 - 0.046 14.3 0.1 0.052 14.1 0.1 1.2 1 0 0 1 1 1 0 Bacteriophage replication protein O PheRS_DBD1 PF18552.1 AAL64013.1 - 0.07 12.9 0.2 0.1 12.3 0.2 1.3 1 1 0 1 1 1 0 PheRS DNA binding domain 1 HTH_20 PF12840.7 AAL64013.1 - 0.081 13.0 0.0 0.1 12.7 0.0 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain Med31 PF05669.12 AAL64013.1 - 0.086 12.9 0.1 0.1 12.6 0.1 1.1 1 0 0 1 1 1 0 SOH1 DDRGK PF09756.9 AAL64014.1 - 0.083 12.5 5.7 0.12 12.0 5.7 1.2 1 0 0 1 1 1 0 DDRGK domain TERB2 PF15101.6 AAL64014.1 - 0.15 12.1 4.5 0.21 11.6 4.5 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Phage_holin_7_1 PF16081.5 AAL64014.1 - 0.21 11.8 5.1 0.3 11.3 3.1 1.9 1 1 1 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family Serinc PF03348.15 AAL64014.1 - 0.3 10.0 0.5 0.37 9.7 0.5 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Presenilin PF01080.17 AAL64014.1 - 0.35 9.6 3.3 0.42 9.3 3.3 1.1 1 0 0 1 1 1 0 Presenilin PHC2_SAM_assoc PF16616.5 AAL64014.1 - 0.49 11.2 6.6 0.9 10.4 6.6 1.3 1 0 0 1 1 1 0 Unstructured region on Polyhomeotic-like protein 1 and 2 Dicty_REP PF05086.12 AAL64014.1 - 0.51 8.3 4.2 0.53 8.2 4.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pannexin_like PF12534.8 AAL64014.1 - 1.2 8.2 4.2 1.5 7.8 4.2 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Ribosomal_S25 PF03297.15 AAL64015.1 - 1.3e-20 73.5 7.1 1.5e-20 73.2 7.1 1.1 1 0 0 1 1 1 1 S25 ribosomal protein TrmB PF01978.19 AAL64015.1 - 0.00055 19.8 0.5 0.00096 19.0 0.2 1.6 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.20 AAL64015.1 - 0.047 14.0 0.2 0.13 12.6 0.0 1.7 1 1 1 2 2 2 0 Transcriptional regulator DUF3235 PF11574.8 AAL64015.1 - 0.068 14.0 1.6 0.096 13.6 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) ZnuA PF01297.17 AAL64015.1 - 0.086 12.2 1.1 0.099 12.0 1.1 1.1 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic PRC2_HTH_1 PF18118.1 AAL64015.1 - 0.11 13.3 2.4 0.14 13.0 2.4 1.2 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain DDRGK PF09756.9 AAL64015.1 - 0.15 11.7 9.9 0.3 10.7 9.8 1.4 1 1 0 1 1 1 0 DDRGK domain Radical_SAM PF04055.21 AAL64017.1 - 1e-13 52.0 0.0 2e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 AAL64017.1 - 2.5e-10 40.8 0.0 5.5e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AAL64017.1 - 3.7e-05 23.8 0.0 8.5e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain RIO1 PF01163.22 AAL64018.1 - 2.4e-11 43.6 0.0 3.1e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 AAL64018.1 - 6.9e-10 38.6 0.0 1.3e-09 37.8 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 AAL64018.1 - 9.4e-08 32.3 0.1 0.00024 21.1 0.2 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 AAL64018.1 - 4.3e-07 29.6 0.0 5.7e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AAL64018.1 - 0.001 18.4 0.0 0.0018 17.6 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 AAL64018.1 - 0.025 14.2 0.0 0.16 11.5 0.0 1.8 1 1 1 2 2 2 0 Choline/ethanolamine kinase WaaY PF06176.11 AAL64018.1 - 0.026 14.2 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) zf-H2C2_2 PF13465.6 AAL64019.1 - 0.019 15.4 1.4 0.78 10.3 0.4 2.4 2 0 0 2 2 2 0 Zinc-finger double domain zf-HIT PF04438.16 AAL64019.1 - 0.034 14.0 2.7 1.3 8.9 0.7 2.4 2 0 0 2 2 2 0 HIT zinc finger PhnA_Zn_Ribbon PF08274.12 AAL64019.1 - 0.052 13.5 1.0 0.082 12.9 0.4 1.7 2 0 0 2 2 2 0 PhnA Zinc-Ribbon DUF723 PF05265.13 AAL64019.1 - 0.052 13.5 1.4 4.2 7.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF723) Zn-ribbon_8 PF09723.10 AAL64019.1 - 0.66 10.1 5.0 8.9 6.5 5.0 2.3 1 1 0 1 1 1 0 Zinc ribbon domain zf-C2H2_4 PF13894.6 AAL64019.1 - 2.1 9.4 4.2 8.6 7.5 0.5 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger DHH PF01368.20 AAL64020.1 - 5.2e-06 26.6 0.1 1.6e-05 25.0 0.1 1.9 2 0 0 2 2 2 1 DHH family DHHA1 PF02272.19 AAL64020.1 - 4.9e-05 23.8 0.3 9e-05 22.9 0.3 1.4 1 0 0 1 1 1 1 DHHA1 domain Prefoldin_2 PF01920.20 AAL64022.1 - 2e-26 92.0 13.4 2.2e-26 91.8 13.4 1.0 1 0 0 1 1 1 1 Prefoldin subunit Enkurin PF13864.6 AAL64022.1 - 0.0047 17.3 7.2 0.016 15.6 0.5 2.4 2 0 0 2 2 2 1 Calmodulin-binding Tho2 PF11262.8 AAL64022.1 - 0.015 14.5 1.8 0.019 14.2 1.8 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 LXG PF04740.12 AAL64022.1 - 0.016 14.9 3.1 1.1 8.9 0.4 2.2 2 0 0 2 2 2 0 LXG domain of WXG superfamily DUF4510 PF14971.6 AAL64022.1 - 0.017 15.5 2.0 0.017 15.5 2.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4510) SbcD_C PF12320.8 AAL64022.1 - 0.036 14.3 5.0 0.087 13.1 5.0 1.7 1 1 0 1 1 1 0 Type 5 capsule protein repressor C-terminal domain CENP-F_leu_zip PF10473.9 AAL64022.1 - 0.039 14.0 10.6 0.57 10.2 0.3 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 T2SSE PF00437.20 AAL64022.1 - 0.058 12.4 0.1 0.068 12.2 0.1 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein Fzo_mitofusin PF04799.13 AAL64022.1 - 0.073 12.6 6.5 0.072 12.6 0.7 2.1 1 1 1 2 2 2 0 fzo-like conserved region Utp12 PF04003.12 AAL64022.1 - 0.077 13.3 1.7 0.13 12.5 0.1 2.0 2 1 0 2 2 2 0 Dip2/Utp12 Family DUF2408 PF10303.9 AAL64022.1 - 0.079 13.5 7.4 0.13 12.8 7.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) DUF1640 PF07798.11 AAL64022.1 - 0.094 12.8 12.1 1.8 8.6 11.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) Elongin_A PF06881.11 AAL64022.1 - 0.097 13.2 4.3 0.12 12.9 4.3 1.1 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A MscS_porin PF12795.7 AAL64022.1 - 0.099 12.2 13.7 0.081 12.5 3.1 2.0 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Tropomyosin PF00261.20 AAL64022.1 - 0.11 11.9 11.2 0.41 10.0 4.1 2.0 2 0 0 2 2 2 0 Tropomyosin Snf7 PF03357.21 AAL64022.1 - 0.17 11.5 7.8 0.74 9.4 2.8 2.1 2 0 0 2 2 2 0 Snf7 DUF948 PF06103.11 AAL64022.1 - 0.22 11.8 3.7 3.7 7.9 0.4 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) FeoB_Cyto PF17910.1 AAL64022.1 - 0.49 11.0 4.3 0.58 10.7 3.3 1.6 1 1 0 1 1 1 0 FeoB cytosolic helical domain Com_YlbF PF06133.11 AAL64022.1 - 0.71 10.5 13.3 0.063 13.9 4.1 2.1 1 1 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA Atg14 PF10186.9 AAL64022.1 - 0.81 8.7 7.8 1.1 8.3 7.8 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 IFT57 PF10498.9 AAL64022.1 - 0.83 8.5 8.9 2.4 7.0 1.2 2.0 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Prefoldin PF02996.17 AAL64022.1 - 0.88 9.5 10.0 9.2 6.2 1.1 2.6 1 1 0 1 1 1 0 Prefoldin subunit CENP-Q PF13094.6 AAL64022.1 - 0.95 9.7 13.4 0.97 9.6 4.9 2.2 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Cauli_AT PF03233.13 AAL64022.1 - 1 9.3 7.0 3.7 7.4 0.6 2.0 1 1 1 2 2 2 0 Aphid transmission protein DHR10 PF18595.1 AAL64022.1 - 1.3 9.1 17.8 0.55 10.3 6.5 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Nup54 PF13874.6 AAL64022.1 - 1.4 9.0 11.6 38 4.4 11.6 2.1 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 FadA PF09403.10 AAL64022.1 - 1.4 9.4 11.6 0.54 10.8 2.6 2.4 1 1 1 2 2 2 0 Adhesion protein FadA XkdW PF09636.10 AAL64022.1 - 1.8 8.7 5.6 0.8 9.8 0.9 2.1 2 0 0 2 2 2 0 XkdW protein FlaC_arch PF05377.11 AAL64022.1 - 1.8 9.0 8.5 1.9 8.9 1.7 2.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) NuA4 PF09340.10 AAL64022.1 - 1.9 8.4 8.0 0.25 11.3 0.4 2.4 2 1 0 2 2 2 0 Histone acetyltransferase subunit NuA4 DUF3450 PF11932.8 AAL64022.1 - 2.3 7.5 14.2 0.91 8.8 3.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF724 PF05266.14 AAL64022.1 - 2.4 7.9 8.8 11 5.8 8.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF724) TPR_MLP1_2 PF07926.12 AAL64022.1 - 2.9 8.0 16.1 45 4.1 16.1 2.2 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4200 PF13863.6 AAL64022.1 - 3 8.3 15.0 1 9.8 4.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Spc7 PF08317.11 AAL64022.1 - 3.9 6.3 14.1 1.5 7.6 2.3 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein Cor1 PF04803.12 AAL64022.1 - 4.7 7.4 12.5 29 4.9 12.5 1.9 1 1 0 1 1 1 0 Cor1/Xlr/Xmr conserved region Spc24 PF08286.11 AAL64022.1 - 7.1 6.9 11.4 9.2 6.6 1.9 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Microtub_bind PF13931.6 AAL64022.1 - 8.1 6.8 9.7 3.3 8.1 0.9 2.0 1 1 1 2 2 2 0 Kinesin-associated microtubule-binding bZIP_1 PF00170.21 AAL64022.1 - 8.5 6.6 14.9 0.69 10.0 6.2 2.6 2 1 0 2 2 2 0 bZIP transcription factor APG6_N PF17675.1 AAL64022.1 - 8.9 6.8 17.3 4.4 7.9 3.2 1.9 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF4763 PF15960.5 AAL64022.1 - 9.3 5.5 14.5 6 6.1 4.5 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4763) Ribosomal_L37ae PF01780.19 AAL64025.1 - 7.7e-30 102.8 0.4 9.1e-30 102.6 0.4 1.1 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 AAL64025.1 - 0.0012 18.8 2.1 0.0019 18.2 2.1 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-C2H2_3 PF13878.6 AAL64025.1 - 0.0071 16.1 0.1 0.82 9.5 0.0 2.2 2 0 0 2 2 2 1 zinc-finger of acetyl-transferase ESCO zf-H2C2_2 PF13465.6 AAL64025.1 - 0.0074 16.7 0.8 1.9 9.0 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger double domain Zn_ribbon_SprT PF17283.2 AAL64025.1 - 0.011 15.7 5.0 0.12 12.4 5.3 2.1 1 1 1 2 2 2 0 SprT-like zinc ribbon domain IBR PF01485.21 AAL64025.1 - 0.017 15.4 0.1 0.026 14.7 0.1 1.3 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zinc_ribbon_5 PF13719.6 AAL64025.1 - 0.021 14.6 1.7 4.3 7.2 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 AAL64025.1 - 0.028 14.5 0.4 4.4 7.5 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain zf-TFIIB PF13453.6 AAL64025.1 - 0.037 13.4 1.3 0.1 12.0 1.3 1.7 1 1 0 1 1 1 0 Transcription factor zinc-finger DZR PF12773.7 AAL64025.1 - 0.037 14.0 0.4 0.07 13.2 0.4 1.5 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_7 PF02591.15 AAL64025.1 - 0.076 13.2 2.2 3.7 7.8 0.1 3.0 3 0 0 3 3 3 0 C4-type zinc ribbon domain zinc_ribbon_10 PF10058.9 AAL64025.1 - 0.088 12.6 2.6 7.2 6.4 3.0 2.3 1 1 1 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein OrfB_Zn_ribbon PF07282.11 AAL64025.1 - 0.12 12.3 0.8 0.27 11.2 0.8 1.6 1 1 0 1 1 1 0 Putative transposase DNA-binding domain HypA PF01155.19 AAL64025.1 - 0.12 12.4 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA UPF0547 PF10571.9 AAL64025.1 - 0.12 12.5 3.6 2.5 8.3 0.6 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zinc_ribbon_4 PF13717.6 AAL64025.1 - 0.13 12.2 4.4 2.6 8.0 0.4 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-RING_4 PF14570.6 AAL64025.1 - 0.18 11.6 1.5 1.2 8.9 0.2 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-ribbon_3 PF13248.6 AAL64025.1 - 0.35 10.3 2.9 5.1 6.7 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf_C2H2_10 PF18414.1 AAL64025.1 - 0.53 9.9 2.6 6 6.5 0.2 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger zf-tcix PF14952.6 AAL64025.1 - 0.55 9.9 5.5 0.65 9.7 0.1 2.2 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding Rubredoxin_2 PF18073.1 AAL64025.1 - 1.1 9.0 8.5 1.2 8.9 0.7 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain DUF4379 PF14311.6 AAL64025.1 - 1.8 9.0 8.3 7.3 7.0 0.7 3.1 2 1 1 3 3 3 0 Probable Zinc-ribbon domain RNase_PH PF01138.21 AAL64026.1 - 2.1e-25 89.8 0.0 3.1e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 AAL64026.1 - 1.5e-10 41.0 1.4 5.8e-10 39.1 0.0 2.7 4 0 0 4 4 4 1 3' exoribonuclease family, domain 2 RNase_PH PF01138.21 AAL64027.1 - 9.7e-36 123.2 0.0 1.3e-35 122.8 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 AAL64027.1 - 2.9e-14 52.8 0.0 7.9e-14 51.4 0.0 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 KH_6 PF15985.5 AAL64028.1 - 1.2e-12 48.0 0.3 2.4e-12 47.0 0.3 1.5 1 0 0 1 1 1 1 KH domain KH_1 PF00013.29 AAL64028.1 - 1.9e-05 24.4 0.2 4.6e-05 23.2 0.1 1.7 2 0 0 2 2 2 1 KH domain KH_2 PF07650.17 AAL64028.1 - 0.0081 16.0 0.1 0.022 14.6 0.1 1.8 1 0 0 1 1 1 1 KH domain ECR1_N PF14382.6 AAL64028.1 - 0.013 15.3 0.0 0.05 13.4 0.0 2.0 2 0 0 2 2 2 0 Exosome complex exonuclease RRP4 N-terminal region KH_4 PF13083.6 AAL64028.1 - 0.018 14.9 0.1 0.14 12.0 0.0 2.3 1 1 1 2 2 2 0 KH domain S1 PF00575.23 AAL64028.1 - 0.038 14.3 2.6 0.094 13.1 0.1 2.6 2 1 0 2 2 2 0 S1 RNA binding domain TcpF PF06340.11 AAL64028.1 - 0.078 11.8 0.1 0.11 11.4 0.1 1.2 1 0 0 1 1 1 0 Vibrio cholerae toxin co-regulated pilus biosynthesis protein F SBDS PF01172.18 AAL64029.1 - 1.1e-22 79.9 0.1 2.4e-22 78.8 0.1 1.6 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 AAL64029.1 - 4.9e-20 71.7 0.8 8e-20 71.0 0.8 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain TEX13 PF15186.6 AAL64029.1 - 0.1 12.3 0.6 0.18 11.5 0.2 1.6 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family TMEM237 PF15383.6 AAL64029.1 - 0.1 11.7 0.1 0.14 11.2 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 237 ThiP_synth PF10120.9 AAL64030.1 - 1.1e-33 116.2 0.1 1.5e-33 115.7 0.1 1.2 1 0 0 1 1 1 1 Thiamine-phosphate synthase HTH_37 PF13744.6 AAL64030.1 - 0.00083 19.3 0.0 0.0021 18.0 0.0 1.7 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 AAL64030.1 - 0.0068 16.4 1.2 0.042 13.9 0.0 2.8 4 0 0 4 4 4 1 Helix-turn-helix HTH_23 PF13384.6 AAL64030.1 - 0.0078 16.0 0.0 0.028 14.2 0.0 1.9 1 0 0 1 1 1 1 Homeodomain-like domain XAF1_C PF18608.1 AAL64030.1 - 0.008 15.7 0.8 0.051 13.1 0.0 2.4 3 0 0 3 3 3 1 XIAP-associated factor 1 C-terminal domain HTH_1 PF00126.27 AAL64030.1 - 0.03 14.3 0.1 0.083 12.9 0.1 1.8 1 1 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family ABC_tran PF00005.27 AAL64031.1 - 0.03 14.8 1.0 1 9.9 1.0 2.5 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 AAL64031.1 - 0.031 14.6 0.0 0.85 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain ALAD PF00490.21 AAL64031.1 - 0.048 12.8 0.0 0.084 12.0 0.0 1.4 2 0 0 2 2 2 0 Delta-aminolevulinic acid dehydratase Latarcin PF10279.9 AAL64032.1 - 0.044 14.2 1.7 1.6 9.1 0.5 2.1 2 0 0 2 2 2 0 Latarcin precursor RNA_binding PF01877.17 AAL64033.1 - 1.5e-27 96.2 0.2 2.9e-27 95.3 0.0 1.5 2 0 0 2 2 2 1 RNA binding Proteasome PF00227.26 AAL64035.1 - 5.7e-58 195.5 0.3 1e-57 194.7 0.1 1.6 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.9 AAL64035.1 - 1.1e-12 47.4 0.3 3.5e-12 45.7 0.1 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Topo-VIb_trans PF09239.11 AAL64036.1 - 5.3e-59 198.6 0.0 9.1e-59 197.8 0.0 1.4 1 0 0 1 1 1 1 Topoisomerase VI B subunit, transducer HATPase_c PF02518.26 AAL64036.1 - 2.5e-11 44.0 0.0 4.7e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 AAL64036.1 - 9.1e-08 32.0 0.0 3.5e-07 30.1 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DASH_Dad3 PF08656.10 AAL64036.1 - 0.04 14.0 4.4 0.037 14.1 2.3 2.0 2 0 0 2 2 2 0 DASH complex subunit Dad3 DUF3969 PF13108.6 AAL64036.1 - 0.15 12.1 1.5 0.36 10.8 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3969) TP6A_N PF04406.14 AAL64037.1 - 4.7e-22 77.7 0.1 1.1e-21 76.6 0.1 1.6 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF2399 PF09664.10 AAL64037.1 - 0.0095 15.9 0.0 0.024 14.5 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2399) PhoU PF01895.19 AAL64038.1 - 1.7e-18 66.8 6.9 3.9e-18 65.7 4.9 2.4 2 0 0 2 2 2 1 PhoU domain MazE_antitoxin PF04014.18 AAL64038.1 - 1.8e-10 40.5 0.2 6.2e-10 38.8 0.2 2.0 1 0 0 1 1 1 1 Antidote-toxin recognition MazE, bacterial antitoxin TOBE PF03459.17 AAL64038.1 - 0.011 16.1 0.1 0.037 14.3 0.1 1.9 2 0 0 2 2 2 0 TOBE domain eIF-1a PF01176.19 AAL64038.1 - 0.011 15.5 0.0 0.032 14.0 0.0 1.8 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 TOBE_2 PF08402.10 AAL64038.1 - 0.06 13.5 0.1 0.16 12.1 0.1 1.8 1 0 0 1 1 1 0 TOBE domain PaRep2a PF07903.11 AAL64039.1 - 0.0015 18.4 0.0 0.0026 17.6 0.0 1.5 1 1 0 1 1 1 1 PaRep2a protein Methyltransf_25 PF13649.6 AAL64041.1 - 0.068 13.9 0.1 0.1 13.3 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 AAL64041.1 - 0.093 12.1 0.5 0.12 11.7 0.5 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 AAL64041.1 - 0.11 13.1 0.1 0.22 12.2 0.1 1.5 1 1 0 1 1 1 0 Methyltransferase domain HTH_20 PF12840.7 AAL64042.1 - 1.4e-07 31.5 0.2 3e-07 30.4 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 AAL64042.1 - 3.8e-07 29.9 0.5 7.8e-07 28.9 0.2 1.7 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 AAL64042.1 - 3.9e-05 23.1 0.3 0.00012 21.5 0.1 1.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 AAL64042.1 - 0.00064 19.6 0.1 0.0015 18.4 0.1 1.6 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 AAL64042.1 - 0.001 18.9 1.0 0.0037 17.1 0.4 2.1 2 0 0 2 2 2 1 MarR family HTH_11 PF08279.12 AAL64042.1 - 0.0022 17.9 0.4 0.0046 16.9 0.4 1.6 1 0 0 1 1 1 1 HTH domain HTH_IclR PF09339.10 AAL64042.1 - 0.035 13.9 0.7 0.081 12.7 0.2 1.9 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_DeoR PF08220.12 AAL64042.1 - 0.067 13.0 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Alba PF01918.21 AAL64043.1 - 4.2e-16 58.5 0.9 5.4e-16 58.2 0.9 1.2 1 0 0 1 1 1 1 Alba Rpp20 PF12328.8 AAL64043.1 - 0.023 14.6 1.3 0.038 13.9 0.5 1.7 1 1 1 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P Phage_SSB PF16773.5 AAL64043.1 - 0.071 13.2 0.2 0.084 12.9 0.2 1.2 1 0 0 1 1 1 0 Lactococcus phage single-stranded DNA binding protein PaRep2a PF07903.11 AAL64044.1 - 3.9e-28 97.7 0.1 7.5e-28 96.8 0.1 1.4 2 0 0 2 2 2 1 PaRep2a protein PaRep2b PF07775.11 AAL64045.1 - 2.2e-245 814.9 13.7 2.7e-245 814.7 13.7 1.0 1 0 0 1 1 1 1 PaRep2b protein PASTA PF03793.19 AAL64045.1 - 0.0019 18.0 0.2 0.69 9.8 0.1 3.6 2 1 1 3 3 3 1 PASTA domain DUF3216 PF11505.8 AAL64045.1 - 0.066 13.4 0.0 0.27 11.5 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) SusF_SusE PF16411.5 AAL64045.1 - 0.12 12.9 0.0 0.31 11.6 0.0 1.9 1 1 0 1 1 1 0 Outer membrane protein SusF_SusE PaRep2b PF07775.11 AAL64046.1 - 7.2e-07 28.1 0.1 7.3e-07 28.0 0.1 1.0 1 0 0 1 1 1 1 PaRep2b protein UbiD PF01977.16 AAL64047.1 - 1.4e-75 254.7 0.0 1.7e-75 254.4 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase DUF521 PF04412.13 AAL64048.1 - 2e-84 283.6 0.0 2.5e-84 283.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF521) VirD1 PF07328.11 AAL64048.1 - 0.15 12.0 0.0 26 4.8 0.0 3.1 2 1 1 3 3 3 0 T-DNA border endonuclease VirD1 DUF126 PF01989.16 AAL64049.1 - 9.5e-19 67.0 0.1 1.6e-18 66.3 0.1 1.4 1 0 0 1 1 1 1 Aconitase X swivel domain AGOG PF09171.10 AAL64050.1 - 1.3e-76 257.2 0.0 1.5e-76 257.0 0.0 1.0 1 0 0 1 1 1 1 N-glycosylase/DNA lyase DUF3517 PF12030.8 AAL64050.1 - 0.056 12.4 0.0 0.13 11.1 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3517) DNA_primase_lrg PF04104.14 AAL64051.1 - 6.9e-35 120.7 0.0 1.6e-34 119.5 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit RXLR_WY PF18634.1 AAL64051.1 - 0.062 13.2 0.0 0.23 11.4 0.0 2.0 1 0 0 1 1 1 0 RXLR phytopathogen effector protein WY-domain PhdYeFM_antitox PF02604.19 AAL64051.1 - 0.13 12.1 0.1 0.3 10.9 0.1 1.6 1 0 0 1 1 1 0 Antitoxin Phd_YefM, type II toxin-antitoxin system KdpC PF02669.15 AAL64051.1 - 0.18 11.6 0.1 0.47 10.3 0.0 1.6 2 0 0 2 2 2 0 K+-transporting ATPase, c chain VWA_2 PF13519.6 AAL64052.1 - 7.1e-09 36.3 0.0 1.6e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 AAL64052.1 - 1.6e-05 24.9 0.0 2.6e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 AAL64052.1 - 1.7e-05 24.3 0.5 3.9e-05 23.2 0.2 1.7 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein VWA PF00092.28 AAL64052.1 - 0.00015 22.1 0.0 0.00045 20.5 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain DUF58 PF01882.18 AAL64052.1 - 0.084 13.2 0.1 0.23 11.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function DUF58 AAA_5 PF07728.14 AAL64053.1 - 5.2e-21 75.1 0.0 8.6e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 AAL64053.1 - 4.7e-19 68.5 0.0 7.3e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 AAL64053.1 - 1.2e-09 38.1 0.0 2.6e-09 37.0 0.0 1.5 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.6 AAL64053.1 - 5.8e-09 36.3 0.0 1.9e-08 34.6 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA PF00004.29 AAL64053.1 - 2.3e-07 31.3 0.0 5.3e-07 30.1 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 AAL64053.1 - 9.5e-07 28.4 0.0 0.00025 20.5 0.0 2.4 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 AAL64053.1 - 9.3e-06 25.5 0.1 0.03 14.1 0.0 2.3 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 AAL64053.1 - 5.3e-05 23.0 0.0 0.0001 22.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain MCM PF00493.23 AAL64053.1 - 5.5e-05 22.4 0.0 8.5e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain AAA_16 PF13191.6 AAL64053.1 - 0.00032 21.1 0.0 0.00083 19.8 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain Sigma54_activ_2 PF14532.6 AAL64053.1 - 0.00035 20.7 0.0 0.0012 19.0 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_14 PF13173.6 AAL64053.1 - 0.00056 19.9 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 AAL64053.1 - 0.0013 18.7 0.0 0.0028 17.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_PrkA PF08298.11 AAL64053.1 - 0.0017 17.3 0.1 0.18 10.7 0.0 2.1 1 1 1 2 2 2 1 PrkA AAA domain TsaE PF02367.17 AAL64053.1 - 0.003 17.5 0.0 0.0062 16.5 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 AAL64053.1 - 0.019 15.1 0.0 0.064 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 AAL64053.1 - 0.021 14.6 0.2 0.12 12.1 0.2 2.1 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 AAL64053.1 - 0.023 15.0 0.1 0.069 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 AAL64053.1 - 0.024 15.0 0.4 2.2 8.6 0.4 2.3 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 AAL64053.1 - 0.03 13.7 0.1 0.25 10.7 0.0 2.1 2 0 0 2 2 2 0 KaiC AAA_7 PF12775.7 AAL64053.1 - 0.031 13.8 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 AAL64053.1 - 0.037 13.9 0.0 0.35 10.8 0.0 2.2 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.6 AAL64053.1 - 0.056 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 AAL64053.1 - 0.068 12.8 0.1 0.15 11.7 0.0 1.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.6 AAL64053.1 - 0.076 13.6 0.0 0.19 12.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.13 AAL64053.1 - 0.092 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain ABC_tran PF00005.27 AAL64053.1 - 0.093 13.2 0.0 0.22 12.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 AAL64053.1 - 0.094 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_21 PF13304.6 AAL64053.1 - 0.11 12.2 0.0 0.93 9.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system PduV-EutP PF10662.9 AAL64053.1 - 0.13 12.0 0.0 0.31 10.8 0.0 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Bombolitin PF08096.11 AAL64053.1 - 0.25 11.7 2.3 9.3 6.8 0.5 3.1 2 0 0 2 2 2 0 Bombolitin family CLP1_P PF16575.5 AAL64054.1 - 1.8e-31 109.4 0.0 2.6e-31 108.9 0.0 1.2 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CbiA PF01656.23 AAL64054.1 - 4.6e-06 26.7 0.1 8.1e-06 25.9 0.1 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 AAL64054.1 - 0.00071 19.1 0.2 0.0014 18.2 0.2 1.4 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase MeaB PF03308.16 AAL64054.1 - 0.0032 16.5 0.0 0.0047 16.0 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_31 PF13614.6 AAL64054.1 - 0.023 14.6 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 AAL64054.1 - 0.032 13.9 0.0 0.062 13.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_29 PF13555.6 AAL64054.1 - 0.039 13.7 0.0 0.081 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain UPF0128 PF03673.13 AAL64054.1 - 0.041 13.4 0.1 0.19 11.2 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0128) AAA_24 PF13479.6 AAL64054.1 - 0.041 13.6 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 AAL64054.1 - 0.048 13.3 1.6 0.11 12.1 0.9 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Metallophos_2 PF12850.7 AAL64055.1 - 7.8e-09 35.9 0.1 1.1e-08 35.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 AAL64055.1 - 2.1e-08 34.9 0.5 4.1e-07 30.7 0.0 1.9 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase CbiA PF01656.23 AAL64056.1 - 7.3e-05 22.8 0.1 0.00015 21.9 0.1 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.6 AAL64056.1 - 0.0011 18.9 0.4 0.43 10.4 0.0 2.2 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 AAL64056.1 - 0.0055 16.4 0.1 0.0099 15.6 0.0 1.5 2 0 0 2 2 2 1 AAA domain ParA PF10609.9 AAL64056.1 - 0.02 14.3 0.6 0.047 13.1 0.3 1.7 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase AAA_31 PF13614.6 AAL64056.1 - 0.023 14.6 0.5 0.17 11.8 0.4 2.0 2 0 0 2 2 2 0 AAA domain Nuc_deoxyri_tr2 PF15891.5 AAL64056.1 - 0.038 14.3 0.0 0.059 13.7 0.0 1.3 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase like Acetyltransf_1 PF00583.25 AAL64057.1 - 3.7e-18 65.9 0.1 5.1e-18 65.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAL64057.1 - 6.8e-13 48.9 0.1 1.1e-12 48.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAL64057.1 - 3.4e-11 43.2 0.0 5.2e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AAL64057.1 - 7.3e-08 32.6 0.0 1.3e-06 28.5 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAL64057.1 - 1.1e-07 31.7 0.0 1.5e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 AAL64057.1 - 9.2e-05 23.1 0.0 0.00012 22.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 AAL64057.1 - 0.00018 21.2 0.0 0.0003 20.5 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AAL64057.1 - 0.00087 19.5 0.0 0.0012 19.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 AAL64057.1 - 0.0062 16.0 0.1 0.032 13.7 0.0 2.0 1 1 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_6 PF13480.7 AAL64057.1 - 0.012 15.8 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 AAL64057.1 - 0.017 14.9 0.1 0.036 13.8 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_CG PF14542.6 AAL64057.1 - 0.024 14.7 0.0 0.049 13.8 0.0 1.5 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 AAL64057.1 - 0.084 12.9 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase AAA_16 PF13191.6 AAL64058.1 - 0.00012 22.5 0.1 0.00089 19.7 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain IncFII_repA PF02387.15 AAL64058.1 - 0.023 13.9 0.7 0.064 12.5 0.3 1.9 2 0 0 2 2 2 0 IncFII RepA protein family AAA_22 PF13401.6 AAL64058.1 - 0.085 13.1 0.5 51 4.1 0.0 3.9 3 1 1 4 4 4 0 AAA domain MarR_2 PF12802.7 AAL64058.1 - 0.24 11.3 0.9 0.77 9.7 0.1 2.3 2 0 0 2 2 2 0 MarR family CdvA PF18822.1 AAL64059.1 - 0.0092 15.8 1.6 0.016 15.1 1.6 1.3 1 0 0 1 1 1 1 CdvA-like coiled-coil domain PTPlike_phytase PF14566.6 AAL64059.1 - 0.017 15.2 0.0 0.022 14.9 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate MukF_M PF17192.4 AAL64059.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 MukF middle domain NurA PF09376.10 AAL64060.1 - 8.6e-11 42.0 1.1 2.6e-10 40.4 1.1 1.8 1 1 0 1 1 1 1 NurA domain Aminotran_1_2 PF00155.21 AAL64061.1 - 4e-57 194.0 0.0 4.6e-57 193.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 AAL64061.1 - 2.8e-08 32.7 0.0 4e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 AAL64061.1 - 1.1e-06 28.3 0.0 1.7e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DUF498 PF04430.14 AAL64061.1 - 0.2 11.7 0.1 0.77 9.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF498/DUF598) PCuAC PF04314.13 AAL64061.1 - 0.21 11.4 0.0 0.66 9.8 0.0 1.7 2 0 0 2 2 2 0 Copper chaperone PCu(A)C NUDIX PF00293.28 AAL64062.1 - 7.6e-14 51.9 0.6 7.6e-14 51.9 0.6 1.4 2 0 0 2 2 2 1 NUDIX domain ssDBP_DBD PF18361.1 AAL64063.1 - 1.6e-60 203.2 2.1 2e-60 202.9 2.1 1.1 1 0 0 1 1 1 1 Single stranded DNA-binding protein ss DNA binding domain ZapB PF06005.12 AAL64063.1 - 0.0029 18.0 3.5 0.0061 17.0 3.5 1.5 1 0 0 1 1 1 1 Cell division protein ZapB Cnn_1N PF07989.11 AAL64063.1 - 0.0033 17.6 1.9 0.0033 17.6 1.9 1.6 2 0 0 2 2 1 1 Centrosomin N-terminal motif 1 bZIP_1 PF00170.21 AAL64063.1 - 0.01 15.9 3.4 0.019 15.0 3.4 1.4 1 0 0 1 1 1 0 bZIP transcription factor DivIC PF04977.15 AAL64063.1 - 0.015 15.1 0.6 0.032 14.0 0.6 1.5 1 0 0 1 1 1 0 Septum formation initiator HALZ PF02183.18 AAL64063.1 - 0.032 14.4 2.7 0.061 13.6 2.7 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Seryl_tRNA_N PF02403.22 AAL64063.1 - 0.043 14.0 1.5 0.15 12.3 1.3 1.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HMMR_C PF15908.5 AAL64063.1 - 0.045 14.0 0.9 0.045 14.0 0.9 2.1 2 1 1 3 3 3 0 Hyaluronan mediated motility receptor C-terminal IFP_35_N PF07334.13 AAL64063.1 - 0.047 13.8 2.1 0.17 12.0 1.6 2.0 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF5320 PF17253.2 AAL64063.1 - 0.054 14.6 4.0 0.12 13.4 0.5 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5320) DUF1192 PF06698.11 AAL64063.1 - 0.39 10.8 3.5 0.87 9.7 3.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) YabA PF06156.13 AAL64063.1 - 0.41 11.3 2.7 0.38 11.4 1.0 1.9 2 1 1 3 3 2 0 Initiation control protein YabA Radical_SAM PF04055.21 AAL64064.1 - 5.9e-10 39.8 0.0 1.3e-09 38.7 0.0 1.6 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 AAL64064.1 - 0.00017 21.8 0.0 0.00028 21.2 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AAL64064.1 - 0.0018 18.4 0.0 0.0038 17.3 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain PhaG_MnhG_YufB PF03334.14 AAL64065.1 - 0.0038 17.4 0.6 0.0038 17.4 0.6 2.0 2 0 0 2 2 2 1 Na+/H+ antiporter subunit TrbC PF04956.13 AAL64065.1 - 0.013 15.7 3.3 0.078 13.2 3.3 1.9 1 1 0 1 1 1 0 TrbC/VIRB2 family DUF2892 PF11127.8 AAL64065.1 - 2.1 8.4 5.3 0.81 9.8 1.6 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2892) FeoB_associated PF12669.7 AAL64065.1 - 7.6 7.0 7.3 23 5.5 0.2 3.0 3 0 0 3 3 3 0 FeoB-associated Cys-rich membrane protein DNA_RNApol_7kD PF03604.13 AAL64067.1 - 1.6e-05 24.5 4.2 4.6e-05 23.0 4.2 1.7 1 1 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit DUF2072 PF09845.9 AAL64067.1 - 0.0029 17.9 0.2 0.0034 17.6 0.2 1.1 1 0 0 1 1 1 1 Zn-ribbon containing protein Zn-ribbon_8 PF09723.10 AAL64067.1 - 0.003 17.7 0.2 0.0041 17.2 0.2 1.3 1 0 0 1 1 1 1 Zinc ribbon domain zf-C2H2 PF00096.26 AAL64067.1 - 0.003 17.9 1.2 0.37 11.3 0.1 2.1 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf_UBZ PF18439.1 AAL64067.1 - 0.0056 16.3 1.3 0.15 11.7 0.1 2.1 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger zf-C2HC5 PF06221.13 AAL64067.1 - 0.0056 16.6 0.3 0.007 16.3 0.3 1.2 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type zf-C2H2_4 PF13894.6 AAL64067.1 - 0.013 16.3 1.2 3.9 8.6 0.1 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger Zn_ribbon_SprT PF17283.2 AAL64067.1 - 0.026 14.4 1.6 0.096 12.6 1.6 1.8 1 1 0 1 1 1 0 SprT-like zinc ribbon domain DZR PF12773.7 AAL64067.1 - 0.039 14.0 0.3 0.079 13.0 0.3 1.6 1 1 0 1 1 1 0 Double zinc ribbon HypA PF01155.19 AAL64067.1 - 0.052 13.6 0.1 0.052 13.6 0.1 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_Tnp_IS1595 PF12760.7 AAL64067.1 - 0.062 13.3 1.1 7.5 6.6 0.1 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain C1_1 PF00130.22 AAL64067.1 - 0.066 13.1 0.3 0.085 12.8 0.3 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TackOD1 PF18551.1 AAL64067.1 - 0.075 12.7 0.2 0.085 12.5 0.2 1.1 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 zf-BED PF02892.15 AAL64067.1 - 0.075 13.1 3.7 1.7 8.7 0.2 2.1 1 1 1 2 2 2 0 BED zinc finger zf-CSL PF05207.13 AAL64067.1 - 0.096 12.4 0.9 0.12 12.1 0.9 1.3 1 1 0 1 1 1 0 CSL zinc finger Mut7-C PF01927.16 AAL64067.1 - 0.1 12.7 0.6 7.7 6.6 0.1 2.0 1 1 1 2 2 2 0 Mut7-C RNAse domain zf_C2H2_6 PF18450.1 AAL64067.1 - 0.27 11.0 2.8 1.1 9.0 0.1 2.4 2 1 0 2 2 2 0 Zinc Finger domain CTP_transf_like PF01467.26 AAL64068.1 - 4e-10 40.0 0.0 9e-10 38.9 0.0 1.5 2 0 0 2 2 2 1 Cytidylyltransferase-like Arm_3 PF16186.5 AAL64068.1 - 0.067 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Atypical Arm repeat Arginase PF00491.21 AAL64069.1 - 8.8e-55 186.2 0.0 1e-54 185.9 0.0 1.0 1 0 0 1 1 1 1 Arginase family Cytidylate_kin PF02224.18 AAL64069.1 - 0.18 11.5 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase Cation_efflux PF01545.21 AAL64070.1 - 1.2e-22 80.7 16.5 1.6e-22 80.2 16.5 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 AAL64070.1 - 0.00017 21.7 0.1 0.00027 21.0 0.1 1.3 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter PaRep2b PF07775.11 AAL64071.1 - 1.4e-271 901.4 16.2 1.6e-271 901.2 16.2 1.0 1 0 0 1 1 1 1 PaRep2b protein SPOR PF05036.13 AAL64071.1 - 0.0079 16.6 0.2 2.8 8.4 0.0 2.7 2 0 0 2 2 2 2 Sporulation related domain Transposon_TraM PF12508.8 AAL64071.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Conjugative transposon, TraM PaRep2a PF07903.11 AAL64072.1 - 2.2e-30 105.0 0.0 4.2e-30 104.1 0.0 1.4 1 0 0 1 1 1 1 PaRep2a protein HGTP_anticodon PF03129.20 AAL64073.1 - 1.6e-18 66.7 0.0 3.6e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 AAL64073.1 - 7e-06 26.1 0.1 6.3e-05 23.0 0.0 2.1 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Zn_ribbon_recom PF13408.6 AAL64073.1 - 0.035 14.6 0.2 5.6 7.6 0.0 2.9 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-C2HC_2 PF13913.6 AAL64073.1 - 0.036 14.0 2.6 0.18 11.7 0.0 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.10 AAL64073.1 - 0.11 12.6 3.0 0.85 9.8 0.0 2.8 3 0 0 3 3 3 0 Zinc ribbon domain zf-ribbon_3 PF13248.6 AAL64073.1 - 0.14 11.6 0.1 0.14 11.6 0.1 2.9 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 AAL64073.1 - 0.16 11.7 2.5 13 5.6 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain ADK_lid PF05191.14 AAL64073.1 - 0.19 11.7 0.7 1 9.4 0.7 2.2 1 1 0 1 1 1 0 Adenylate kinase, active site lid zinc_ribbon_4 PF13717.6 AAL64073.1 - 0.2 11.6 1.1 9.4 6.2 0.0 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Peptidase_S55 PF05580.12 AAL64074.1 - 0.16 11.9 0.1 0.21 11.5 0.1 1.1 1 0 0 1 1 1 0 SpoIVB peptidase S55 tRNA_int_endo PF01974.17 AAL64075.1 - 1.5e-25 89.1 1.0 1.5e-25 89.0 0.1 1.6 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 AAL64075.1 - 1e-21 76.3 1.3 1.5e-21 75.8 1.3 1.2 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain tRNA_int_end_N2 PF12928.7 AAL64075.1 - 0.028 14.6 0.2 0.093 12.9 0.0 1.9 2 0 0 2 2 2 0 tRNA-splicing endonuclease subunit sen54 N-term HSP20 PF00011.21 AAL64076.1 - 2e-09 37.5 0.0 2.4e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 AAL64076.1 - 1.1e-06 28.1 0.0 1.8e-06 27.4 0.0 1.4 1 1 0 1 1 1 1 HSP20-like domain found in ArsA zf-C2HC_2 PF13913.6 AAL64077.1 - 2.1e-05 24.3 4.4 0.0035 17.2 0.4 2.2 2 0 0 2 2 2 2 zinc-finger of a C2HC-type Cys_rich_CPXG PF14255.6 AAL64077.1 - 0.00026 20.8 2.0 0.025 14.5 0.2 2.2 2 0 0 2 2 2 1 Cysteine-rich CPXCG zinc_ribbon_4 PF13717.6 AAL64077.1 - 0.00029 20.7 4.6 0.0032 17.3 4.6 2.1 1 1 0 1 1 1 1 zinc-ribbon domain zf_UBZ PF18439.1 AAL64077.1 - 0.00032 20.2 0.8 0.053 13.1 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger CpXC PF14353.6 AAL64077.1 - 0.00037 20.5 1.7 0.43 10.6 0.2 2.1 1 1 1 2 2 2 2 CpXC protein zf-ribbon_3 PF13248.6 AAL64077.1 - 0.00085 18.6 2.5 0.4 10.2 0.1 2.2 2 0 0 2 2 2 2 zinc-ribbon domain Rad50_zn_hook PF04423.14 AAL64077.1 - 0.0013 18.6 0.2 0.33 10.8 0.0 2.2 2 0 0 2 2 2 1 Rad50 zinc hook motif Cys_rich_KTR PF14205.6 AAL64077.1 - 0.002 17.9 0.1 0.0027 17.5 0.1 1.2 1 0 0 1 1 1 1 Cysteine-rich KTR HypA PF01155.19 AAL64077.1 - 0.0023 17.9 0.0 0.0025 17.8 0.0 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_5 PF13719.6 AAL64077.1 - 0.0033 17.2 1.0 1.3 8.8 0.1 2.2 2 0 0 2 2 2 2 zinc-ribbon domain zinc_ribbon_9 PF14369.6 AAL64077.1 - 0.0036 17.5 0.5 1.3 9.3 0.0 2.2 2 0 0 2 2 2 1 zinc-ribbon Elf1 PF05129.13 AAL64077.1 - 0.0052 16.8 0.1 0.0077 16.3 0.1 1.3 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Trm112p PF03966.16 AAL64077.1 - 0.0069 16.9 2.0 0.17 12.5 2.0 2.2 1 1 0 1 1 1 1 Trm112p-like protein YacG PF03884.14 AAL64077.1 - 0.0071 16.1 0.9 1.5 8.6 0.1 2.2 2 0 0 2 2 2 1 DNA gyrase inhibitor YacG zf-Di19 PF05605.12 AAL64077.1 - 0.0087 16.3 2.2 0.14 12.4 0.2 2.1 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding DZR PF12773.7 AAL64077.1 - 0.0087 16.1 0.1 0.016 15.2 0.1 1.5 1 1 0 1 1 1 1 Double zinc ribbon zf-AN1 PF01428.16 AAL64077.1 - 0.0099 16.0 2.4 1 9.6 0.2 2.1 2 0 0 2 2 2 1 AN1-like Zinc finger ADK_lid PF05191.14 AAL64077.1 - 0.01 15.8 1.4 0.32 11.0 0.1 2.2 2 0 0 2 2 2 0 Adenylate kinase, active site lid TackOD1 PF18551.1 AAL64077.1 - 0.012 15.3 0.1 0.013 15.1 0.1 1.1 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 IBR PF01485.21 AAL64077.1 - 0.015 15.6 2.0 0.64 10.3 0.1 2.0 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-CHCC PF10276.9 AAL64077.1 - 0.015 15.3 1.2 1.1 9.4 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger domain Lar_restr_allev PF14354.6 AAL64077.1 - 0.02 15.3 0.5 0.026 14.9 0.5 1.2 1 0 0 1 1 1 0 Restriction alleviation protein Lar C1_4 PF07975.12 AAL64077.1 - 0.024 14.9 0.1 0.54 10.5 0.0 2.0 2 0 0 2 2 2 0 TFIIH C1-like domain zf-RING_7 PF02591.15 AAL64077.1 - 0.029 14.6 1.1 4 7.7 0.1 2.2 2 0 0 2 2 2 0 C4-type zinc ribbon domain zinc_ribbon_2 PF13240.6 AAL64077.1 - 0.03 14.0 3.6 1.7 8.5 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain FYDLN_acid PF09538.10 AAL64077.1 - 0.035 14.8 1.2 8.1 7.2 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-H2C2_2 PF13465.6 AAL64077.1 - 0.036 14.5 3.9 2.3 8.8 0.4 2.2 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.26 AAL64077.1 - 0.042 14.3 5.7 0.37 11.3 0.2 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type Zn-ribbon_8 PF09723.10 AAL64077.1 - 0.048 13.8 1.8 0.13 12.4 1.8 1.7 1 1 0 1 1 1 0 Zinc ribbon domain T4_baseplate PF12322.8 AAL64077.1 - 0.051 13.0 0.5 2.5 7.5 0.2 2.0 1 1 1 2 2 2 0 T4 bacteriophage base plate protein Sgf11 PF08209.11 AAL64077.1 - 0.056 13.0 2.7 2.1 8.0 0.1 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-DNL PF05180.12 AAL64077.1 - 0.072 13.0 0.5 0.097 12.6 0.5 1.2 1 0 0 1 1 1 0 DNL zinc finger UPF0547 PF10571.9 AAL64077.1 - 0.074 13.1 3.8 1.8 8.7 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 A2L_zn_ribbon PF08792.10 AAL64077.1 - 0.076 12.8 2.2 1.2 8.9 0.2 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain Zn_Tnp_IS1 PF03811.13 AAL64077.1 - 0.09 12.5 2.6 2.8 7.7 0.2 2.1 2 0 0 2 2 2 0 InsA N-terminal domain TRAF6_Z2 PF18048.1 AAL64077.1 - 0.092 12.9 0.8 5.1 7.3 0.1 2.2 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 Anti-TRAP PF15777.5 AAL64077.1 - 0.099 12.6 0.6 0.19 11.7 0.5 1.6 1 1 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein DUF35_N PF12172.8 AAL64077.1 - 0.12 12.3 1.2 5 7.1 0.2 2.2 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF983 PF06170.12 AAL64077.1 - 0.14 12.6 0.2 5 7.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF983) zf-C2H2_4 PF13894.6 AAL64077.1 - 0.15 13.0 3.6 3.2 8.8 0.2 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-DNA_Pol PF08996.10 AAL64077.1 - 0.15 11.8 1.0 8.2 6.1 1.5 2.0 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger Zn_Tnp_IS1595 PF12760.7 AAL64077.1 - 0.17 11.9 5.1 2.6 8.1 0.4 2.1 1 1 1 2 2 2 0 Transposase zinc-ribbon domain DUF2256 PF10013.9 AAL64077.1 - 0.17 12.0 2.1 12 6.1 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) FANCL_C PF11793.8 AAL64077.1 - 0.25 11.6 0.2 0.25 11.6 0.2 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain TF_Zn_Ribbon PF08271.12 AAL64077.1 - 0.29 10.7 5.5 6.1 6.4 5.6 2.1 1 1 1 2 2 2 0 TFIIB zinc-binding TFIIS_C PF01096.18 AAL64077.1 - 0.54 10.1 3.7 8.5 6.3 0.4 2.1 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf_C2H2_10 PF18414.1 AAL64077.1 - 1.2 8.7 6.4 0.5 10.0 0.6 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger Nitroreductase PF00881.24 AAL64078.1 - 1.4e-22 80.6 1.2 6.8e-22 78.3 1.2 1.9 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 AAL64078.1 - 6.4e-07 29.2 0.0 0.025 14.2 0.0 2.4 2 0 0 2 2 2 2 Putative TM nitroreductase Arcadin_1 PF18653.1 AAL64079.1 - 3.8e-43 146.1 0.5 4.2e-43 145.9 0.5 1.0 1 0 0 1 1 1 1 Arcadin 1 Actin PF00022.19 AAL64080.1 - 7.9e-09 34.6 0.1 3e-07 29.4 0.1 2.1 1 1 0 1 1 1 1 Actin AP_endonuc_2_N PF07582.12 AAL64080.1 - 0.13 12.1 0.1 0.41 10.4 0.1 1.9 1 0 0 1 1 1 0 AP endonuclease family 2 C terminus RNase_J_C PF17770.1 AAL64081.1 - 0.1 13.7 0.1 0.2 12.7 0.1 1.5 1 0 0 1 1 1 0 Ribonuclease J C-terminal domain SMC_N PF02463.19 AAL64082.1 - 4.5e-19 68.8 0.0 1.1e-18 67.5 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 AAL64082.1 - 1e-11 45.2 4.8 1.8e-06 27.9 0.3 3.4 1 1 1 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 AAL64082.1 - 3.7e-09 37.4 55.1 5.6 7.4 55.1 4.9 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 AAL64082.1 - 1.5e-07 31.5 0.4 7.9e-05 22.6 0.2 2.9 2 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system GAS PF13851.6 AAL64082.1 - 6.3e-05 22.4 57.2 0.012 15.0 3.6 5.4 3 1 2 5 5 5 4 Growth-arrest specific micro-tubule binding AAA_29 PF13555.6 AAL64082.1 - 0.00025 20.7 0.0 0.00045 19.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Rad50_zn_hook PF04423.14 AAL64082.1 - 0.018 14.9 0.0 0.018 14.9 0.0 5.4 5 0 0 5 5 5 0 Rad50 zinc hook motif ABC_tran PF00005.27 AAL64082.1 - 0.11 13.0 7.4 5.2 7.6 0.2 4.2 3 2 0 3 3 3 0 ABC transporter OmpH PF03938.14 AAL64082.1 - 0.12 12.7 40.6 0.19 12.1 7.5 5.0 3 1 1 4 4 4 0 Outer membrane protein (OmpH-like) FPP PF05911.11 AAL64082.1 - 0.2 9.8 35.7 0.0048 15.2 6.2 3.2 3 0 0 3 3 3 0 Filament-like plant protein, long coiled-coil NdhM PF10664.9 AAL64082.1 - 0.36 11.1 5.6 1.4 9.2 0.6 3.2 2 1 0 2 2 2 0 Cyanobacterial and plastid NDH-1 subunit M DUF948 PF06103.11 AAL64082.1 - 1 9.7 17.4 3.9 7.8 0.2 5.4 5 2 1 6 6 6 0 Bacterial protein of unknown function (DUF948) Flg_hook PF02120.16 AAL64082.1 - 1.1 9.2 4.0 26 4.8 0.0 3.7 3 0 0 3 3 2 0 Flagellar hook-length control protein FliK SesA PF17107.5 AAL64082.1 - 2.4 8.4 14.4 7.4 6.8 6.1 4.5 2 2 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF1664 PF07889.12 AAL64082.1 - 3.2 7.8 27.5 3.8 7.6 0.5 5.7 4 2 0 6 6 5 0 Protein of unknown function (DUF1664) AAA_25 PF13481.6 AAL64082.1 - 3.4 7.2 6.1 3.2 7.3 0.0 3.7 4 2 0 4 4 4 0 AAA domain Syntaxin-6_N PF09177.11 AAL64082.1 - 3.5 8.3 33.9 6 7.5 5.9 6.3 2 2 3 5 5 5 0 Syntaxin 6, N-terminal zf-CpG_bind_C PF12269.8 AAL64082.1 - 4 7.1 17.8 2.1 8.1 3.0 4.2 1 1 2 3 3 3 0 CpG binding protein zinc finger C terminal domain BLOC1_2 PF10046.9 AAL64082.1 - 4.6 7.6 36.8 3.1 8.1 7.0 6.3 3 2 3 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TRPM_tetra PF16519.5 AAL64082.1 - 6.3 7.0 14.6 0.29 11.3 2.6 4.3 3 0 0 3 3 3 0 Tetramerisation domain of TRPM TAF8_C PF10406.9 AAL64082.1 - 8.3 7.1 6.4 1.7 9.2 1.3 2.7 2 0 0 2 2 1 0 Transcription factor TFIID complex subunit 8 C-term T3SS_ATPase_C PF18269.1 AAL64082.1 - 9.7 6.1 8.6 2.2 8.2 0.5 3.9 4 0 0 4 4 3 0 T3SS EscN ATPase C-terminal domain TrmB PF01978.19 AAL64083.1 - 5.7e-22 77.4 0.2 2.5e-21 75.3 0.0 2.1 1 1 1 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 AAL64083.1 - 1.4e-06 27.8 0.0 3.1e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 AAL64083.1 - 0.00011 21.9 0.0 0.00024 20.9 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_27 PF13463.6 AAL64083.1 - 0.00068 20.1 0.0 0.0024 18.3 0.0 1.8 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_29 PF13551.6 AAL64083.1 - 0.0016 18.4 0.0 0.0026 17.7 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix Rrf2 PF02082.20 AAL64083.1 - 0.0059 16.9 0.0 0.037 14.4 0.0 2.0 2 0 0 2 2 2 1 Transcriptional regulator HTH_11 PF08279.12 AAL64083.1 - 0.011 15.6 0.0 0.03 14.3 0.0 1.7 1 0 0 1 1 1 0 HTH domain HTH_IclR PF09339.10 AAL64083.1 - 0.012 15.4 0.1 0.076 12.8 0.0 2.3 3 0 0 3 3 3 0 IclR helix-turn-helix domain MarR_2 PF12802.7 AAL64083.1 - 0.02 14.7 0.0 0.088 12.7 0.0 2.0 2 0 0 2 2 2 0 MarR family Penicillinase_R PF03965.16 AAL64083.1 - 0.023 15.1 0.0 0.042 14.2 0.0 1.5 1 0 0 1 1 1 0 Penicillinase repressor FtsK_gamma PF09397.10 AAL64083.1 - 0.036 13.9 0.0 0.074 12.9 0.0 1.5 1 0 0 1 1 1 0 Ftsk gamma domain HTH_28 PF13518.6 AAL64083.1 - 0.046 13.9 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Fe_dep_repress PF01325.19 AAL64083.1 - 0.048 13.9 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_20 PF12840.7 AAL64083.1 - 0.063 13.3 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain DUF2250 PF10007.9 AAL64083.1 - 0.073 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) Clp_N PF02861.20 AAL64083.1 - 0.076 13.2 0.1 0.8 9.9 0.0 2.3 2 0 0 2 2 2 0 Clp amino terminal domain, pathogenicity island component HTH_9 PF08221.11 AAL64083.1 - 0.12 12.5 0.0 0.52 10.5 0.0 2.1 3 0 0 3 3 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Radical_SAM PF04055.21 AAL64084.1 - 1.6e-21 77.4 2.1 2.2e-21 76.9 0.0 2.3 3 0 0 3 3 3 1 Radical SAM superfamily Fer4_14 PF13394.6 AAL64084.1 - 1.1e-05 25.5 0.0 4.3e-05 23.6 0.0 2.0 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 AAL64084.1 - 1.7e-05 25.1 0.0 3.3e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain YdaS_antitoxin PF15943.5 AAL64084.1 - 0.11 12.4 0.0 0.43 10.5 0.0 2.1 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT ComA PF02679.15 AAL64084.1 - 0.15 11.5 0.0 0.36 10.3 0.0 1.5 2 0 0 2 2 2 0 (2R)-phospho-3-sulfolactate synthase (ComA) ParD_antitoxin PF03693.14 AAL64085.1 - 0.036 14.5 1.0 5.3 7.5 0.0 2.5 2 0 0 2 2 2 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH UXS1_N PF11803.8 AAL64085.1 - 0.064 13.6 0.0 0.61 10.5 0.0 2.5 2 0 0 2 2 2 0 UDP-glucuronate decarboxylase N-terminal CspB_prodomain PF18425.1 AAL64085.1 - 0.07 13.1 0.3 0.33 11.0 0.3 2.2 1 0 0 1 1 1 0 Csp protease B prodomain TPR_MLP1_2 PF07926.12 AAL64085.1 - 1.1 9.3 4.0 13 5.9 0.0 3.4 2 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein MCPsignal PF00015.21 AAL64085.1 - 1.3 8.8 16.1 47 3.7 0.1 3.5 1 1 2 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain ABC_tran PF00005.27 AAL64086.1 - 3.5e-34 118.3 0.0 4.6e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAL64086.1 - 3e-11 43.7 0.1 8.7e-08 32.3 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAL64086.1 - 8.3e-06 25.4 0.0 0.0035 16.8 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAL64086.1 - 0.0004 20.1 0.1 0.00076 19.2 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AAL64086.1 - 0.00045 20.2 0.1 0.00086 19.2 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 AAL64086.1 - 0.00082 19.8 0.0 0.0013 19.1 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AAL64086.1 - 0.00088 19.6 0.1 0.0069 16.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 AAL64086.1 - 0.0013 19.2 0.1 0.012 16.0 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 AAL64086.1 - 0.003 17.3 0.1 0.0071 16.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 AAL64086.1 - 0.0033 16.5 0.1 0.0052 15.9 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_28 PF13521.6 AAL64086.1 - 0.0093 16.2 0.0 0.02 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 AAL64086.1 - 0.0097 15.8 0.0 0.033 14.1 0.0 1.8 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_25 PF13481.6 AAL64086.1 - 0.014 15.0 0.1 0.039 13.5 0.1 1.7 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 AAL64086.1 - 0.015 14.9 0.1 0.027 14.1 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 AAL64086.1 - 0.017 15.6 0.0 0.11 13.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 AAL64086.1 - 0.023 14.4 0.2 0.044 13.4 0.1 1.6 2 0 0 2 2 1 0 SRP54-type protein, GTPase domain Gtr1_RagA PF04670.12 AAL64086.1 - 0.027 13.8 0.1 0.047 13.0 0.1 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region RuvB_N PF05496.12 AAL64086.1 - 0.032 14.0 0.1 0.09 12.5 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 AAL64086.1 - 0.047 13.6 0.0 0.11 12.4 0.0 1.6 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 AAL64086.1 - 0.049 13.4 0.1 0.073 12.8 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AAL64086.1 - 0.052 14.1 0.0 0.086 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AAL64086.1 - 0.083 13.0 0.0 0.16 12.2 0.0 1.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 AAL64086.1 - 0.09 12.5 0.1 0.59 9.8 0.0 2.1 2 1 0 2 2 2 0 IstB-like ATP binding protein Rad17 PF03215.15 AAL64086.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain NB-ARC PF00931.22 AAL64086.1 - 0.12 11.6 0.0 1.1 8.4 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain DnaB_C PF03796.15 AAL64086.1 - 0.12 11.6 0.1 0.25 10.7 0.1 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain RNA_helicase PF00910.22 AAL64086.1 - 0.14 12.5 0.0 0.26 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 AAL64086.1 - 0.14 12.5 0.2 0.37 11.1 0.1 1.6 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 AAL64086.1 - 0.19 11.8 0.0 0.33 10.9 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FtsX PF02687.21 AAL64087.1 - 1.8e-12 47.5 4.2 1.8e-12 47.5 4.2 3.1 3 0 0 3 3 3 2 FtsX-like permease family MacB_PCD PF12704.7 AAL64087.1 - 6.3e-11 43.0 4.1 6.3e-11 43.0 4.1 1.9 2 0 0 2 2 2 1 MacB-like periplasmic core domain MMPL PF03176.15 AAL64088.1 - 4.2e-68 229.7 45.3 3.3e-43 147.9 12.4 2.7 3 0 0 3 3 3 2 MMPL family HTH_24 PF13412.6 AAL64089.1 - 0.0077 15.8 0.1 0.041 13.4 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 AAL64089.1 - 0.053 13.4 0.0 0.058 13.3 0.0 1.1 1 0 0 1 1 1 0 MarR family HAD_2 PF13419.6 AAL64090.1 - 3.5e-07 30.5 0.0 4.2e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAL64090.1 - 8.6e-06 26.2 0.0 3.8e-05 24.1 0.0 1.9 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AAL64090.1 - 0.0014 19.1 0.0 0.0019 18.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AAL64090.1 - 0.0099 15.9 0.0 0.027 14.5 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like ATP_bind_3 PF01171.20 AAL64092.1 - 1.7e-11 44.2 0.0 3.1e-11 43.4 0.0 1.4 1 1 0 1 1 1 1 PP-loop family RecR PF02132.15 AAL64092.1 - 0.00027 20.4 5.9 0.0015 18.1 0.2 3.3 3 0 0 3 3 3 1 RecR protein zn-ribbon_14 PF16503.5 AAL64092.1 - 0.0031 17.0 1.7 0.0031 17.0 1.7 2.8 2 1 0 2 2 2 1 Zinc-ribbon tRNA_Me_trans PF03054.16 AAL64092.1 - 0.005 15.7 0.0 0.007 15.2 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase PAPS_reduct PF01507.19 AAL64092.1 - 0.0072 16.4 0.0 0.55 10.2 0.0 2.2 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family DZR PF12773.7 AAL64092.1 - 0.056 13.5 6.9 1.6 8.8 0.8 2.4 2 0 0 2 2 2 0 Double zinc ribbon Glyco_transf_4 PF13439.6 AAL64092.1 - 0.087 12.8 0.1 0.33 10.9 0.0 1.9 1 1 1 2 2 2 0 Glycosyltransferase Family 4 zf-B_box PF00643.24 AAL64092.1 - 0.63 10.2 4.9 4.8 7.4 0.3 2.3 2 0 0 2 2 2 0 B-box zinc finger zf-ribbon_3 PF13248.6 AAL64092.1 - 1.1 8.8 4.8 2 7.9 1.5 2.6 2 0 0 2 2 2 0 zinc-ribbon domain ACT PF01842.25 AAL64093.1 - 1.7e-10 40.5 0.3 3.7e-10 39.4 0.3 1.5 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 AAL64093.1 - 2.9e-07 31.0 0.3 5.3e-07 30.1 0.3 1.4 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 AAL64093.1 - 0.00012 21.9 0.0 0.00023 21.1 0.0 1.4 1 0 0 1 1 1 1 ACT domain ACT_7 PF13840.6 AAL64093.1 - 0.0004 20.1 0.0 0.0046 16.7 0.0 2.4 3 0 0 3 3 3 1 ACT domain ACT_5 PF13710.6 AAL64093.1 - 0.045 13.6 0.1 0.073 12.9 0.1 1.4 1 0 0 1 1 1 0 ACT domain tRNA-synt_1 PF00133.22 AAL64094.1 - 9.3e-104 347.8 0.0 1.5e-102 343.8 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 AAL64094.1 - 2.4e-31 108.8 0.7 4.5e-31 107.9 0.7 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 AAL64094.1 - 2.8e-21 75.7 0.0 2.2e-13 49.8 0.0 3.3 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 AAL64094.1 - 0.0051 16.3 0.1 0.28 10.7 0.0 2.3 1 1 1 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 AAL64094.1 - 0.16 11.3 0.0 3.2 7.0 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain DEAD PF00270.29 AAL64095.1 - 2.7e-27 95.7 0.0 7.8e-27 94.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AAL64095.1 - 3.4e-18 66.0 0.0 6.5e-16 58.7 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1998 PF09369.10 AAL64095.1 - 1.6e-12 48.0 0.1 5.1e-12 46.4 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) ResIII PF04851.15 AAL64095.1 - 0.00086 19.3 0.0 0.002 18.2 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Glyco_transf_4 PF13439.6 AAL64095.1 - 0.65 10.0 3.1 7.6 6.5 0.9 2.7 1 1 2 3 3 3 0 Glycosyltransferase Family 4 HTH_IclR PF09339.10 AAL64096.1 - 0.00026 20.7 0.1 0.00044 20.0 0.1 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_24 PF13412.6 AAL64096.1 - 0.00072 19.1 0.0 0.0016 17.9 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding TrmB PF01978.19 AAL64096.1 - 0.0011 18.8 0.2 0.0022 17.9 0.2 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB GntR PF00392.21 AAL64096.1 - 0.0045 16.6 0.2 0.013 15.2 0.1 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_Crp_2 PF13545.6 AAL64096.1 - 0.012 15.6 0.2 0.028 14.4 0.2 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Rrf2 PF02082.20 AAL64096.1 - 0.023 15.0 0.0 0.098 13.0 0.0 2.0 2 0 0 2 2 2 0 Transcriptional regulator ABC_membrane PF00664.23 AAL64097.1 - 6.4e-10 39.1 8.1 6.4e-10 39.1 8.1 1.9 2 1 0 2 2 2 1 ABC transporter transmembrane region Nucleos_tra2_C PF07662.13 AAL64097.1 - 0.083 12.7 0.2 0.083 12.7 0.2 2.7 3 0 0 3 3 3 0 Na+ dependent nucleoside transporter C-terminus MFS_1 PF07690.16 AAL64098.1 - 1.8e-26 92.9 63.8 3.7e-22 78.7 40.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 AAL64098.1 - 1.6e-05 24.0 26.4 0.00075 18.5 8.0 2.3 2 0 0 2 2 2 2 MFS_1 like family Adenosine_kin PF04008.14 AAL64099.1 - 4.4e-73 244.2 0.5 4.9e-73 244.0 0.5 1.0 1 0 0 1 1 1 1 Adenosine specific kinase FUR PF01475.19 AAL64100.1 - 1.6e-21 76.7 0.1 1.9e-21 76.5 0.1 1.1 1 0 0 1 1 1 1 Ferric uptake regulator family PadR PF03551.14 AAL64100.1 - 0.00021 21.2 0.0 0.00065 19.6 0.0 1.8 2 0 0 2 2 2 1 Transcriptional regulator PadR-like family Penicillinase_R PF03965.16 AAL64100.1 - 0.00029 21.1 0.0 0.00041 20.7 0.0 1.4 1 1 0 1 1 1 1 Penicillinase repressor TrmB PF01978.19 AAL64100.1 - 0.0011 18.8 0.1 0.004 17.0 0.1 2.0 1 1 1 2 2 2 1 Sugar-specific transcriptional regulator TrmB Pyr_excise PF03013.14 AAL64100.1 - 0.025 14.6 0.0 0.2 11.6 0.0 2.1 2 1 0 2 2 2 0 Pyrimidine dimer DNA glycosylase LexA_DNA_bind PF01726.16 AAL64100.1 - 0.031 14.0 0.0 0.08 12.7 0.0 1.7 1 1 0 1 1 1 0 LexA DNA binding domain HTH_27 PF13463.6 AAL64100.1 - 0.073 13.6 0.1 0.27 11.8 0.0 2.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain HTH_24 PF13412.6 AAL64100.1 - 0.089 12.4 0.1 0.29 10.7 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 AAL64100.1 - 0.092 12.6 0.2 0.65 9.9 0.2 2.3 1 1 0 1 1 1 0 Bacterial regulatory protein, arsR family NAD_binding_5 PF07994.12 AAL64100.1 - 0.1 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase DUF3427 PF11907.8 AAL64100.1 - 0.13 11.6 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3427) Methyltransf_23 PF13489.6 AAL64100.1 - 0.15 11.9 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DAO PF01266.24 AAL64101.1 - 1.3e-54 186.1 0.5 1.5e-54 185.9 0.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AAL64101.1 - 1.9e-06 28.0 0.2 5.1e-06 26.6 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AAL64101.1 - 6.9e-06 25.5 0.1 8.6e-05 21.9 0.1 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AAL64101.1 - 1.8e-05 24.0 0.2 8.7e-05 21.8 0.2 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 AAL64101.1 - 0.00028 20.3 0.5 0.26 10.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 AAL64101.1 - 0.00086 18.6 0.1 0.0016 17.7 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 AAL64101.1 - 0.0042 17.6 0.1 0.19 12.3 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AAL64101.1 - 0.0057 15.4 0.0 0.33 9.6 0.1 2.4 3 0 0 3 3 3 1 HI0933-like protein FAD_oxidored PF12831.7 AAL64101.1 - 0.031 13.6 0.2 0.06 12.7 0.2 1.4 1 1 1 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 AAL64101.1 - 0.045 13.8 0.9 0.35 10.9 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.22 AAL64101.1 - 0.055 12.6 0.4 4.1 6.4 0.1 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A TrkA_N PF02254.18 AAL64101.1 - 0.055 13.7 0.1 0.34 11.2 0.0 2.2 1 1 1 2 2 2 0 TrkA-N domain Mqo PF06039.15 AAL64101.1 - 0.14 10.7 0.0 0.19 10.2 0.0 1.1 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) AlaDh_PNT_C PF01262.21 AAL64101.1 - 0.14 11.4 0.1 0.25 10.6 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ATP-grasp_2 PF08442.10 AAL64103.1 - 1.1e-66 224.2 1.1 1.2e-66 224.1 0.3 1.5 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 AAL64103.1 - 3.3e-17 62.7 0.6 8e-17 61.5 0.4 1.7 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.6 AAL64103.1 - 1.8e-12 47.2 0.9 7.5e-12 45.2 0.9 2.0 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 AAL64103.1 - 6.7e-09 35.6 0.1 1.4e-08 34.5 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain GARS_A PF01071.19 AAL64103.1 - 0.00022 21.0 0.1 0.00053 19.8 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp PF02222.22 AAL64103.1 - 0.00039 20.0 0.1 0.00069 19.2 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain CoA_binding PF02629.19 AAL64104.1 - 2.2e-31 108.4 3.5 1e-30 106.3 0.6 2.4 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 AAL64104.1 - 2.2e-12 47.1 0.1 4.3e-12 46.1 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 AAL64104.1 - 6.4e-11 42.2 0.0 1.1e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 AAL64104.1 - 1.2e-08 35.4 1.0 2.5e-08 34.4 0.4 1.9 2 0 0 2 2 2 1 CoA binding domain GFO_IDH_MocA PF01408.22 AAL64104.1 - 0.0064 17.3 0.4 0.04 14.7 0.2 2.2 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Radical_SAM PF04055.21 AAL64104.1 - 0.16 12.3 0.1 1.7 9.0 0.0 2.5 2 1 0 2 2 2 0 Radical SAM superfamily Aminotran_1_2 PF00155.21 AAL64105.1 - 3e-39 135.2 0.0 3.3e-39 135.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 AAL64105.1 - 1.7e-13 50.2 0.0 2.9e-13 49.4 0.0 1.4 2 0 0 2 2 2 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.17 AAL64105.1 - 0.018 14.4 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family PALP PF00291.25 AAL64106.1 - 2.2e-88 296.5 3.5 2.7e-88 296.2 3.5 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ACT PF01842.25 AAL64106.1 - 1.5e-09 37.4 0.1 5.3e-09 35.7 0.0 1.9 2 0 0 2 2 2 1 ACT domain ACT_7 PF13840.6 AAL64106.1 - 0.0034 17.2 1.1 0.22 11.4 0.0 2.8 2 1 0 2 2 2 1 ACT domain ACT_6 PF13740.6 AAL64106.1 - 0.08 12.9 0.0 0.33 10.9 0.0 2.0 1 1 0 1 1 1 0 ACT domain tRNA_SAD PF07973.14 AAL64107.1 - 2.7e-12 46.6 0.3 4.6e-12 45.8 0.3 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.19 AAL64107.1 - 2e-07 29.9 0.1 2.9e-07 29.4 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) Na_H_Exchanger PF00999.21 AAL64108.1 - 1.5e-14 53.6 51.2 1.5e-14 53.6 51.2 2.4 2 1 0 2 2 2 1 Sodium/hydrogen exchanger family DUF5518 PF17647.1 AAL64108.1 - 0.00092 19.3 11.5 0.00092 19.3 11.5 6.0 4 2 1 5 5 5 1 Family of unknown function (DUF5518) HD PF01966.22 AAL64110.1 - 5e-06 26.7 0.2 9e-06 25.9 0.2 1.4 1 0 0 1 1 1 1 HD domain TRI12 PF06609.13 AAL64110.1 - 0.063 11.7 0.0 0.088 11.2 0.0 1.1 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) CutA1 PF03091.15 AAL64111.1 - 1.9e-39 133.5 0.8 2.2e-39 133.3 0.8 1.0 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein PhosphMutase PF10143.9 AAL64112.1 - 4.3e-51 173.2 0.0 6.5e-51 172.6 0.0 1.3 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Metalloenzyme PF01676.18 AAL64112.1 - 1e-33 116.8 0.0 1.3e-33 116.4 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Alk_phosphatase PF00245.20 AAL64112.1 - 0.001 18.1 0.1 0.005 15.8 0.1 1.8 1 1 0 1 1 1 1 Alkaline phosphatase MAF_flag10 PF01973.18 AAL64114.1 - 2.1e-08 34.1 0.0 3.4e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF115 MFS_1 PF07690.16 AAL64115.1 - 3.9e-54 183.9 66.4 1.7e-48 165.4 37.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AAL64115.1 - 5.8e-41 140.8 22.4 4.1e-31 108.3 5.4 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 AAL64115.1 - 4.1e-13 49.4 26.4 5.5e-13 49.0 26.4 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 AAL64115.1 - 0.011 14.6 21.7 0.038 12.9 1.6 3.0 1 1 2 4 4 4 0 MFS_1 like family DUF3017 PF11222.8 AAL64115.1 - 0.022 15.0 7.2 0.048 13.9 0.6 3.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3017) 2TM PF13239.6 AAL64115.1 - 1.9 8.9 0.0 1.9 8.9 0.0 4.3 5 0 0 5 5 5 0 2TM domain tRNA_deacylase PF04414.12 AAL64116.1 - 2.1e-39 135.2 0.0 2.9e-39 134.7 0.0 1.1 1 0 0 1 1 1 1 D-aminoacyl-tRNA deacylase SpoU_sub_bind PF08032.12 AAL64116.1 - 0.091 13.1 0.4 0.18 12.1 0.4 1.4 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding Ribosomal_L25p PF01386.19 AAL64116.1 - 0.14 12.7 0.3 0.77 10.3 0.0 2.1 2 0 0 2 2 2 0 Ribosomal L25p family ADH_N PF08240.12 AAL64117.1 - 2e-29 101.6 0.1 3.2e-29 101.0 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AAL64117.1 - 6.5e-20 71.4 0.0 1.8e-18 66.7 0.0 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AAL64117.1 - 1.4e-14 55.2 0.1 2.4e-14 54.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 AAL64117.1 - 0.0011 18.3 1.6 0.002 17.4 1.6 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 AAL64117.1 - 0.0016 18.5 0.1 0.0033 17.5 0.1 1.5 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF1188 PF06690.11 AAL64117.1 - 0.0016 18.0 0.1 0.0023 17.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1188) 2-Hacid_dh_C PF02826.19 AAL64117.1 - 0.0024 17.3 0.1 0.0041 16.5 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 AAL64117.1 - 0.0038 16.9 0.1 0.0072 16.0 0.1 1.5 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 AAL64117.1 - 0.033 13.4 0.1 0.059 12.6 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAL64117.1 - 0.069 13.7 0.5 0.13 12.8 0.5 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF364 PF04016.12 AAL64117.1 - 0.08 12.5 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 Putative heavy-metal chelation TrkA_N PF02254.18 AAL64117.1 - 0.1 12.9 0.2 1.7 8.9 0.1 2.1 1 1 1 2 2 2 0 TrkA-N domain 3HCDH_N PF02737.18 AAL64117.1 - 0.13 12.1 0.4 0.19 11.6 0.4 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 AAL64117.1 - 0.15 11.2 0.6 0.2 10.8 0.6 1.2 1 0 0 1 1 1 0 FAD binding domain AMP-binding PF00501.28 AAL64118.1 - 1.1e-87 294.5 0.0 1.3e-87 294.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAL64118.1 - 1.3e-22 80.6 0.1 3.5e-22 79.2 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Peptidase_M20 PF01546.28 AAL64119.1 - 3e-42 144.7 0.1 4e-42 144.3 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AAL64119.1 - 3.3e-21 75.2 0.0 7.6e-21 74.1 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Nitroreductase PF00881.24 AAL64120.1 - 1.3e-33 116.5 0.0 1.6e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 AAL64120.1 - 1.7e-07 31.0 0.0 0.00076 19.1 0.0 2.2 2 0 0 2 2 2 2 Putative TM nitroreductase Ubie_methyltran PF01209.18 AAL64122.1 - 1.9e-13 50.3 0.1 4.5e-13 49.1 0.1 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 AAL64122.1 - 4e-09 37.0 0.0 7.3e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAL64122.1 - 1.2e-07 32.3 0.0 3.3e-07 30.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAL64122.1 - 0.0015 19.2 0.0 0.0052 17.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAL64122.1 - 0.0021 17.9 0.0 0.0026 17.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAL64122.1 - 0.0041 16.9 0.0 0.032 14.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain PCC_BT PF18140.1 AAL64122.1 - 0.11 12.9 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 Propionyl-coenzyme A carboxylase BT domain PGM_PMM_I PF02878.16 AAL64123.1 - 0.076 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I Methyltransf_23 PF13489.6 AAL64123.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Zn-ribbon_8 PF09723.10 AAL64124.1 - 0.038 14.1 0.1 0.11 12.6 0.1 1.8 2 0 0 2 2 2 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 AAL64124.1 - 0.066 13.2 0.6 0.17 11.9 0.3 1.8 1 1 1 2 2 2 0 Transposase zinc-ribbon domain COPI_C PF06957.11 AAL64124.1 - 0.081 11.7 0.1 0.11 11.2 0.1 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus zf-RING_7 PF02591.15 AAL64124.1 - 0.22 11.8 1.2 11 6.3 0.1 3.0 3 1 0 3 3 3 0 C4-type zinc ribbon domain UPF0126 PF03458.13 AAL64128.1 - 6.6e-39 131.7 20.2 8.4e-22 76.8 1.8 2.5 3 0 0 3 3 3 2 UPF0126 domain 2_5_RNA_ligase2 PF13563.6 AAL64130.1 - 5.7e-08 32.8 0.1 6.1e-07 29.5 0.1 1.9 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily ABC_tran PF00005.27 AAL64131.1 - 1.5e-37 129.2 0.0 1.3e-18 67.8 0.0 2.5 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 AAL64131.1 - 1.2e-12 47.7 1.0 2.5e-05 23.8 0.0 3.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain RLI PF04068.15 AAL64131.1 - 2.6e-12 46.3 4.6 6.7e-12 45.0 4.6 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.6 AAL64131.1 - 1.7e-10 41.2 3.6 0.011 15.6 0.0 4.2 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system Fer4_6 PF12837.7 AAL64131.1 - 7.8e-08 32.1 14.4 9.1e-05 22.4 3.1 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4 PF00037.27 AAL64131.1 - 2.7e-07 30.1 3.9 2.7e-07 30.1 3.9 2.7 3 0 0 3 3 2 1 4Fe-4S binding domain AAA PF00004.29 AAL64131.1 - 3.4e-05 24.3 0.2 0.33 11.4 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Fer4_21 PF14697.6 AAL64131.1 - 0.00011 22.3 9.8 0.00021 21.4 9.8 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain RuvB_N PF05496.12 AAL64131.1 - 0.00012 21.8 0.0 0.29 10.9 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain Fer4_7 PF12838.7 AAL64131.1 - 0.00015 22.3 9.0 0.00098 19.7 0.5 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAL64131.1 - 0.00019 21.3 9.9 0.00066 19.6 0.5 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_10 PF13237.6 AAL64131.1 - 0.00023 21.2 11.9 0.0039 17.3 12.4 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain MMR_HSR1 PF01926.23 AAL64131.1 - 0.0003 20.8 0.4 0.1 12.7 0.0 2.8 2 2 0 2 2 2 1 50S ribosome-binding GTPase AAA_24 PF13479.6 AAL64131.1 - 0.0012 18.6 0.5 0.23 11.2 0.1 2.3 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 AAL64131.1 - 0.0019 18.4 0.0 4 7.7 0.0 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Fer4_9 PF13187.6 AAL64131.1 - 0.0024 18.0 10.0 0.0052 16.9 9.6 1.8 1 1 0 1 1 1 1 4Fe-4S dicluster domain AAA_14 PF13173.6 AAL64131.1 - 0.0027 17.7 0.4 3.6 7.6 0.1 2.8 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 AAL64131.1 - 0.0033 17.2 0.5 0.45 10.2 0.1 3.1 3 0 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 AAL64131.1 - 0.0034 17.3 0.2 0.19 11.6 0.1 2.8 3 0 0 3 3 2 1 RsgA GTPase Fer4_16 PF13484.6 AAL64131.1 - 0.012 16.6 7.3 0.049 14.6 1.1 2.5 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain RNA_helicase PF00910.22 AAL64131.1 - 0.016 15.6 0.0 4.7 7.7 0.0 2.9 3 0 0 3 3 2 0 RNA helicase IstB_IS21 PF01695.17 AAL64131.1 - 0.032 14.0 0.4 0.8 9.4 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein NACHT PF05729.12 AAL64131.1 - 0.035 14.0 0.9 0.22 11.4 0.1 2.3 2 0 0 2 2 2 0 NACHT domain Rad17 PF03215.15 AAL64131.1 - 0.038 13.9 0.3 9.6 6.1 0.0 2.7 3 0 0 3 3 3 0 Rad17 P-loop domain AAA_33 PF13671.6 AAL64131.1 - 0.041 14.0 1.8 0.64 10.2 0.1 3.0 2 2 0 2 2 2 0 AAA domain MobB PF03205.14 AAL64131.1 - 0.06 13.2 1.5 1.6 8.6 0.2 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.6 AAL64131.1 - 0.066 13.5 0.2 2 8.7 0.0 2.8 2 2 0 2 2 2 0 AAA domain AAA_29 PF13555.6 AAL64131.1 - 0.096 12.4 0.3 3.3 7.5 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_25 PF13481.6 AAL64131.1 - 0.11 12.1 1.9 2.7 7.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 AAL64131.1 - 0.13 12.6 0.1 1.8 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain RecA PF00154.21 AAL64131.1 - 0.14 11.6 0.1 6.9 6.1 0.0 2.3 2 0 0 2 2 2 0 recA bacterial DNA recombination protein AAA_23 PF13476.6 AAL64131.1 - 0.14 12.7 2.2 2.1 8.8 0.1 2.5 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.22 AAL64131.1 - 0.37 9.9 2.4 4.4 6.4 0.2 2.3 2 0 0 2 2 2 0 NB-ARC domain TsaE PF02367.17 AAL64131.1 - 0.53 10.3 3.5 2.3 8.2 0.0 3.0 4 0 0 4 4 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Fer4_8 PF13183.6 AAL64131.1 - 0.96 9.9 7.1 0.21 12.1 0.3 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAL64131.1 - 1.4 9.5 9.6 32 5.2 9.7 2.4 1 1 0 1 1 1 0 4Fe-4S dicluster domain NTPase_1 PF03266.15 AAL64131.1 - 1.5 8.7 5.5 4.2 7.3 0.3 3.3 3 0 0 3 3 3 0 NTPase Fer4_4 PF12800.7 AAL64131.1 - 1.6 9.4 14.3 0.63 10.7 2.6 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_3 PF12798.7 AAL64131.1 - 4.1 8.6 17.2 3 9.0 4.4 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Glucos_trans_II PF14264.6 AAL64132.1 - 0.013 14.9 5.0 0.014 14.8 5.0 1.0 1 0 0 1 1 1 0 Glucosyl transferase GtrII PKD_channel PF08016.12 AAL64132.1 - 0.43 9.2 4.8 8 5.0 4.8 2.0 1 1 0 1 1 1 0 Polycystin cation channel DUF4131 PF13567.6 AAL64132.1 - 0.59 9.8 4.2 0.71 9.5 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Glycos_transf_2 PF00535.26 AAL64133.1 - 4.3e-14 52.7 0.0 5.9e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 AAL64133.1 - 2.3e-09 36.9 0.0 4.2e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 AAL64133.1 - 2.8e-09 37.2 0.0 4.3e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF1404 PF07185.11 AAL64133.1 - 0.0042 16.8 0.4 0.0077 16.0 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1404) RHH_1 PF01402.21 AAL64134.1 - 3.3e-06 26.8 0.2 1e-05 25.3 0.2 1.8 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family PsiB PF06290.11 AAL64136.1 - 0.089 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Plasmid SOS inhibition protein (PsiB) Arm-DNA-bind_1 PF09003.10 AAL64136.1 - 0.12 12.6 0.1 0.25 11.5 0.1 1.5 1 0 0 1 1 1 0 Bacteriophage lambda integrase, Arm DNA-binding domain DUF4471 PF14740.6 AAL64137.1 - 0.044 13.0 0.0 0.062 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) Hexapep PF00132.24 AAL64137.1 - 0.059 13.1 0.0 12 5.8 0.0 3.6 3 2 1 4 4 4 0 Bacterial transferase hexapeptide (six repeats) DEAD PF00270.29 AAL64138.1 - 6.4e-33 114.0 0.0 2.5e-32 112.0 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase DEAD_assoc PF08494.11 AAL64138.1 - 8.5e-31 107.2 0.1 2e-30 106.0 0.1 1.7 1 0 0 1 1 1 1 DEAD/H associated Helicase_C PF00271.31 AAL64138.1 - 1.1e-19 70.8 0.0 3.5e-18 66.0 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 AAL64138.1 - 1.4e-10 41.4 0.0 3.4e-10 40.2 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_11 PF13086.6 AAL64138.1 - 0.004 17.0 0.0 0.11 12.3 0.0 3.0 3 1 1 4 4 4 1 AAA domain AAA_25 PF13481.6 AAL64138.1 - 0.054 13.1 0.0 0.16 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 AAL64138.1 - 0.078 13.3 0.0 0.35 11.2 0.0 2.1 1 1 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 AAL64138.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain SNF2_N PF00176.23 AAL64138.1 - 0.14 10.9 0.0 0.24 10.1 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain CBS PF00571.28 AAL64140.1 - 6.7e-46 154.6 14.5 5.3e-13 49.2 0.0 4.1 4 0 0 4 4 4 4 CBS domain DUF4894 PF16235.5 AAL64140.1 - 0.0041 17.5 0.2 0.021 15.2 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4894) Ham1p_like PF01725.16 AAL64141.1 - 5.6e-50 169.9 0.0 6.3e-50 169.7 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Thioredoxin_3 PF13192.6 AAL64142.1 - 1.1e-15 57.4 1.4 2.9e-11 43.3 0.3 2.5 3 0 0 3 3 3 2 Thioredoxin domain Thioredoxin PF00085.20 AAL64142.1 - 1.9e-06 27.8 0.1 5.1e-05 23.2 0.0 2.3 2 1 0 2 2 2 1 Thioredoxin TraF PF13728.6 AAL64142.1 - 0.0028 17.5 0.0 0.012 15.5 0.0 1.9 3 0 0 3 3 3 1 F plasmid transfer operon protein ABC_transp_aux PF09822.9 AAL64142.1 - 0.0039 16.7 0.0 0.0081 15.7 0.0 1.5 1 1 1 2 2 2 1 ABC-type uncharacterized transport system Thioredoxin_2 PF13098.6 AAL64142.1 - 0.0057 17.1 1.9 0.048 14.1 0.4 2.9 2 2 0 2 2 2 1 Thioredoxin-like domain DSBA PF01323.20 AAL64142.1 - 0.15 11.9 0.3 0.28 10.9 0.1 1.7 1 1 0 1 1 1 0 DSBA-like thioredoxin domain Sigma70_r1_1 PF03979.14 AAL64143.1 - 0.038 14.0 0.1 0.1 12.6 0.0 1.7 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 SnAPC_2_like PF11035.8 AAL64143.1 - 0.045 13.9 0.4 0.056 13.6 0.4 1.0 1 0 0 1 1 1 0 Small nuclear RNA activating complex subunit 2, SNAP190 Myb KH_5 PF13184.6 AAL64143.1 - 0.05 13.7 0.0 0.15 12.2 0.0 1.7 2 0 0 2 2 2 0 NusA-like KH domain Peptidase_S49_N PF08496.10 AAL64143.1 - 0.14 12.3 5.0 0.22 11.6 5.0 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal D5_N PF08706.11 AAL64143.1 - 0.15 12.3 2.7 0.19 12.0 2.7 1.1 1 0 0 1 1 1 0 D5 N terminal like AP3D1 PF06375.11 AAL64143.1 - 1.3 9.3 8.7 1.5 9.0 8.7 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Ldh_1_N PF00056.23 AAL64144.1 - 5.1e-41 140.1 0.1 7.6e-41 139.5 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 AAL64144.1 - 8.3e-19 68.1 0.0 1.3e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.16 AAL64144.1 - 2.6e-06 27.1 0.6 7.8e-05 22.3 0.0 2.5 3 0 0 3 3 3 1 Family 4 glycosyl hydrolase UDPG_MGDP_dh_N PF03721.14 AAL64144.1 - 0.0097 15.5 2.6 0.012 15.2 0.8 2.1 2 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PEP_hydrolase PF09370.10 AAL64144.1 - 0.087 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like Pyr_redox_2 PF07992.14 AAL64145.1 - 5.7e-66 222.7 6.3 7.1e-66 222.4 6.3 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAL64145.1 - 4.9e-24 84.7 13.8 2.9e-19 69.4 1.1 3.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAL64145.1 - 1e-20 74.2 2.8 8e-18 64.7 0.3 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 AAL64145.1 - 1.7e-17 63.7 0.8 1e-16 61.1 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain DAO PF01266.24 AAL64145.1 - 8.6e-11 42.0 16.7 0.00049 19.8 1.2 4.1 2 2 2 4 4 4 3 FAD dependent oxidoreductase HI0933_like PF03486.14 AAL64145.1 - 3.8e-09 35.7 9.3 0.0035 16.1 0.6 4.3 3 1 1 4 4 4 3 HI0933-like protein K_oxygenase PF13434.6 AAL64145.1 - 2.2e-08 33.7 0.6 3.5e-06 26.4 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 AAL64145.1 - 1.6e-07 31.5 1.8 0.00028 21.0 0.4 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 AAL64145.1 - 5.5e-06 25.7 9.1 0.0032 16.6 1.7 3.5 2 2 1 3 3 3 3 Glucose inhibited division protein A NAD_binding_9 PF13454.6 AAL64145.1 - 7.9e-05 22.7 7.1 3.1 7.8 0.0 4.2 4 0 0 4 4 4 2 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 AAL64145.1 - 0.0004 19.7 4.1 0.031 13.6 0.9 2.6 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 AAL64145.1 - 0.0011 19.3 1.6 1.8 9.0 0.1 2.8 2 1 0 2 2 2 2 Putative NAD(P)-binding FAD_binding_2 PF00890.24 AAL64145.1 - 0.0034 16.5 9.1 0.058 12.5 5.3 2.7 1 1 1 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 AAL64145.1 - 0.0061 15.6 2.1 0.028 13.5 0.5 2.4 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_oxidored PF12831.7 AAL64145.1 - 0.007 15.8 15.6 0.0073 15.7 2.5 3.5 3 1 1 4 4 4 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 AAL64145.1 - 0.0091 15.3 3.0 0.56 9.4 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain 2-Hacid_dh_C PF02826.19 AAL64145.1 - 0.027 13.8 0.3 0.2 11.0 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 AAL64145.1 - 0.034 13.0 0.1 0.034 13.0 0.1 2.3 3 0 0 3 3 3 0 Tryptophan halogenase ocr PF08684.10 AAL64145.1 - 0.041 14.3 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 DNA mimic ocr GMC_oxred_N PF00732.19 AAL64145.1 - 0.084 12.2 0.2 0.27 10.6 0.0 2.0 3 0 0 3 3 3 0 GMC oxidoreductase TrkA_N PF02254.18 AAL64145.1 - 0.095 13.0 0.3 4.9 7.4 0.1 2.6 2 0 0 2 2 2 0 TrkA-N domain 3HCDH_N PF02737.18 AAL64145.1 - 0.11 12.3 1.0 0.5 10.2 0.1 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UbiA PF01040.18 AAL64147.1 - 1.8e-31 109.4 23.0 2.3e-31 109.0 23.0 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family MFS_1 PF07690.16 AAL64148.1 - 3.9e-21 75.4 45.5 1e-12 47.7 21.9 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Ribosomal_L6 PF00347.23 AAL64149.1 - 8.6e-22 77.6 5.5 2.8e-10 40.7 0.7 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 Cob_adeno_trans PF01923.18 AAL64150.1 - 1e-13 51.7 0.0 2e-13 50.8 0.0 1.4 1 1 0 1 1 1 1 Cobalamin adenosyltransferase Unstab_antitox PF09720.10 AAL64150.1 - 0.06 13.4 0.5 0.12 12.5 0.5 1.4 1 0 0 1 1 1 0 Putative addiction module component CBS PF00571.28 AAL64152.1 - 6.3e-25 87.4 3.8 1.3e-13 51.2 0.2 2.1 2 0 0 2 2 2 2 CBS domain Ribosomal_L9_C PF03948.14 AAL64152.1 - 0.025 15.1 0.1 4.5 7.8 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein L9, C-terminal domain Cas_csx3 PF09620.10 AAL64152.1 - 0.052 13.4 1.3 0.11 12.4 0.1 1.9 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_csx3) HTH_21 PF13276.6 AAL64152.1 - 0.3 11.3 2.0 2.4 8.4 0.1 2.7 2 1 1 3 3 3 0 HTH-like domain Usp PF00582.26 AAL64153.1 - 1.8e-37 129.0 0.8 2e-37 128.8 0.8 1.0 1 0 0 1 1 1 1 Universal stress protein family DNA_photolyase PF00875.18 AAL64153.1 - 0.022 14.8 0.1 0.029 14.4 0.1 1.2 1 0 0 1 1 1 0 DNA photolyase PGM_PMM_I PF02878.16 AAL64153.1 - 0.044 13.5 0.0 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I MFS_1 PF07690.16 AAL64154.1 - 1.4e-13 50.5 23.1 1.4e-13 50.5 23.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DDOST_48kD PF03345.14 AAL64154.1 - 0.1 11.4 0.5 0.22 10.3 0.2 1.6 2 0 0 2 2 2 0 Oligosaccharyltransferase 48 kDa subunit beta IncD PF17628.2 AAL64154.1 - 3.8 7.3 6.1 1.3 8.8 2.3 2.1 1 1 1 2 2 2 0 Inclusion membrane protein D MFS_1 PF07690.16 AAL64155.1 - 2.6e-11 43.1 13.4 3.1e-11 42.8 13.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 AAL64155.1 - 7.2e-05 21.8 5.3 9.7e-05 21.4 5.3 1.2 1 0 0 1 1 1 1 MFS_1 like family MFS_3 PF05977.13 AAL64155.1 - 0.00087 17.8 1.2 0.0012 17.4 1.2 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector DUF21 PF01595.20 AAL64155.1 - 0.35 10.6 3.8 0.5 10.0 3.8 1.2 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain DUF3433 PF11915.8 AAL64156.1 - 1.5 9.3 6.2 0.34 11.4 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3433) TauE PF01925.19 AAL64157.1 - 3e-41 141.6 46.0 3.4e-41 141.4 46.0 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE Sec61_beta PF03911.16 AAL64158.1 - 3.3e-09 36.6 0.5 3.7e-09 36.4 0.5 1.1 1 0 0 1 1 1 1 Sec61beta family SBP_bac_5 PF00496.22 AAL64159.1 - 3.7e-89 299.3 0.1 4.9e-89 298.9 0.1 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle DUF2749 PF10907.8 AAL64159.1 - 0.098 12.8 1.0 0.21 11.8 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) BPD_transp_1 PF00528.22 AAL64160.1 - 2e-25 89.6 9.3 2e-25 89.6 9.3 1.9 3 0 0 3 3 3 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 AAL64160.1 - 0.0021 18.0 1.9 0.0021 18.0 1.9 4.2 5 0 0 5 5 5 1 N-terminal TM domain of oligopeptide transport permease C BPD_transp_1 PF00528.22 AAL64161.1 - 1.2e-37 129.5 20.7 1.6e-37 129.0 15.1 2.1 2 0 0 2 2 2 2 Binding-protein-dependent transport system inner membrane component CbiA PF01656.23 AAL64165.1 - 8.4e-05 22.6 0.0 0.00011 22.2 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 AAL64165.1 - 0.0024 17.8 0.3 0.014 15.3 0.2 2.1 2 0 0 2 2 2 1 AAA domain ParA PF10609.9 AAL64165.1 - 0.011 15.2 0.1 0.023 14.2 0.1 1.5 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase ArsA_ATPase PF02374.15 AAL64165.1 - 0.37 9.9 2.2 0.39 9.8 0.4 1.9 3 0 0 3 3 3 0 Anion-transporting ATPase T2SSE PF00437.20 AAL64166.1 - 3.1e-11 42.8 0.0 4.9e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_28 PF13521.6 AAL64166.1 - 0.0055 17.0 0.0 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 AAL64166.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region IF2_N PF04760.15 AAL64168.1 - 0.042 13.7 0.7 0.092 12.6 0.7 1.6 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region DUF2267 PF10025.9 AAL64168.1 - 0.081 13.2 0.4 0.1 12.9 0.4 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) T2SSF PF00482.23 AAL64168.1 - 0.11 12.5 0.1 0.67 9.9 0.1 2.0 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F Trypan_glycop PF00913.19 AAL64168.1 - 0.42 9.8 2.3 0.39 9.9 2.3 1.3 1 1 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) PDR_CDR PF06422.12 AAL64169.1 - 0.035 14.0 0.1 0.1 12.5 0.1 1.7 1 0 0 1 1 1 0 CDR ABC transporter MpPF26 PF07666.11 AAL64169.1 - 0.14 12.3 4.4 0.056 13.6 1.5 1.7 2 0 0 2 2 2 0 M penetrans paralogue family 26 DUF2207 PF09972.9 AAL64169.1 - 3.3 6.4 9.6 1.5 7.5 1.5 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF4407 PF14362.6 AAL64171.1 - 1.6e-05 24.4 9.4 2.8e-05 23.6 9.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Spc7 PF08317.11 AAL64171.1 - 2.7e-05 23.2 18.8 3.8e-05 22.7 18.8 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein SHE3 PF17078.5 AAL64171.1 - 6.4e-05 22.8 8.1 8.9e-05 22.3 8.1 1.1 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 EzrA PF06160.12 AAL64171.1 - 0.00011 20.6 10.4 0.00015 20.1 10.4 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA APG6_N PF17675.1 AAL64171.1 - 0.00013 22.5 25.2 0.00043 20.8 24.4 1.9 1 1 0 1 1 1 1 Apg6 coiled-coil region ATG16 PF08614.11 AAL64171.1 - 0.00018 21.8 19.9 0.00018 21.8 19.9 2.0 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) Troponin PF00992.20 AAL64171.1 - 0.00033 21.0 10.5 0.00045 20.5 9.1 1.7 1 1 1 2 2 2 1 Troponin FUSC PF04632.12 AAL64171.1 - 0.00042 19.0 11.8 0.00067 18.3 11.8 1.3 1 0 0 1 1 1 1 Fusaric acid resistance protein family Tropomyosin PF00261.20 AAL64171.1 - 0.00053 19.4 17.6 0.0017 17.8 17.4 1.7 1 1 0 1 1 1 1 Tropomyosin CEP63 PF17045.5 AAL64171.1 - 0.00076 19.5 11.4 0.00076 19.5 11.4 1.7 1 1 0 1 1 1 1 Centrosomal protein of 63 kDa TMF_DNA_bd PF12329.8 AAL64171.1 - 0.0014 18.6 7.7 0.0014 18.6 7.7 2.8 1 1 2 3 3 3 1 TATA element modulatory factor 1 DNA binding Tropomyosin_1 PF12718.7 AAL64171.1 - 0.0017 18.5 13.1 0.0017 18.5 13.1 1.8 1 1 1 2 2 2 1 Tropomyosin like BicD PF09730.9 AAL64171.1 - 0.0019 16.8 13.9 0.082 11.3 3.9 2.0 1 1 1 2 2 2 2 Microtubule-associated protein Bicaudal-D Syntaxin_2 PF14523.6 AAL64171.1 - 0.0019 18.6 11.1 0.056 13.8 1.7 2.5 1 1 1 2 2 2 1 Syntaxin-like protein DUF641 PF04859.12 AAL64171.1 - 0.0025 18.1 13.4 0.0043 17.4 10.7 2.5 1 1 1 2 2 2 1 Plant protein of unknown function (DUF641) TolA_bind_tri PF16331.5 AAL64171.1 - 0.0026 17.8 6.7 0.0026 17.8 6.7 3.2 1 1 2 3 3 3 1 TolA binding protein trimerisation CENP-F_leu_zip PF10473.9 AAL64171.1 - 0.0029 17.7 18.0 0.034 14.2 5.1 2.2 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_PEP_C PF04513.12 AAL64171.1 - 0.0033 17.5 13.3 0.0058 16.7 13.3 1.4 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus GAS PF13851.6 AAL64171.1 - 0.0042 16.5 18.1 0.016 14.6 17.6 1.8 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding Filament PF00038.21 AAL64171.1 - 0.0049 16.5 19.1 0.029 14.0 12.9 2.0 1 1 1 2 2 2 1 Intermediate filament protein Lebercilin PF15619.6 AAL64171.1 - 0.0053 16.4 15.9 0.0079 15.9 15.9 1.2 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease TACC_C PF05010.14 AAL64171.1 - 0.0063 16.3 10.3 0.0089 15.8 10.3 1.2 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal CREPT PF16566.5 AAL64171.1 - 0.0082 16.3 8.9 0.015 15.5 8.9 1.4 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour Cluap1 PF10234.9 AAL64171.1 - 0.0092 15.4 13.1 0.014 14.8 13.1 1.2 1 0 0 1 1 1 1 Clusterin-associated protein-1 BAR_2 PF10455.9 AAL64171.1 - 0.0098 15.1 7.1 0.014 14.6 7.1 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking FlaC_arch PF05377.11 AAL64171.1 - 0.011 16.1 2.7 3.8 8.0 0.1 3.7 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) HAUS-augmin3 PF14932.6 AAL64171.1 - 0.011 15.3 14.8 0.019 14.6 14.8 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 FapA PF03961.13 AAL64171.1 - 0.012 14.2 7.6 0.096 11.3 7.7 1.9 1 1 0 1 1 1 0 Flagellar Assembly Protein A ADIP PF11559.8 AAL64171.1 - 0.014 15.5 25.2 0.21 11.6 10.8 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding BLOC1_2 PF10046.9 AAL64171.1 - 0.017 15.4 14.1 0.13 12.5 4.0 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 KASH_CCD PF14662.6 AAL64171.1 - 0.023 14.6 14.0 0.039 13.8 14.0 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF4201 PF13870.6 AAL64171.1 - 0.023 14.4 13.7 0.054 13.2 13.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) DUF3584 PF12128.8 AAL64171.1 - 0.026 12.1 17.3 0.039 11.5 17.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF3450 PF11932.8 AAL64171.1 - 0.031 13.6 23.8 0.16 11.3 6.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TMF_TATA_bd PF12325.8 AAL64171.1 - 0.033 14.4 16.9 0.076 13.2 14.6 2.1 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Fez1 PF06818.15 AAL64171.1 - 0.034 14.6 14.5 0.066 13.7 14.5 1.4 1 1 0 1 1 1 0 Fez1 AAA_13 PF13166.6 AAL64171.1 - 0.035 12.8 7.1 0.06 12.0 7.1 1.3 1 0 0 1 1 1 0 AAA domain IFT57 PF10498.9 AAL64171.1 - 0.04 12.9 10.2 0.074 12.0 10.0 1.4 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 DUF2959 PF11172.8 AAL64171.1 - 0.044 13.9 13.3 0.035 14.3 9.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2959) Prominin PF05478.11 AAL64171.1 - 0.045 11.7 7.6 0.065 11.2 7.6 1.1 1 0 0 1 1 1 0 Prominin TPR_MLP1_2 PF07926.12 AAL64171.1 - 0.047 13.8 25.9 1.9 8.5 26.0 2.2 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein AIP3 PF03915.13 AAL64171.1 - 0.049 12.7 6.0 0.068 12.3 6.0 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 DUF724 PF05266.14 AAL64171.1 - 0.052 13.4 10.6 0.087 12.6 10.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) FPP PF05911.11 AAL64171.1 - 0.052 11.7 11.9 0.089 11.0 11.9 1.3 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Atg14 PF10186.9 AAL64171.1 - 0.054 12.6 16.2 0.073 12.1 16.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DASH_Dad4 PF08650.10 AAL64171.1 - 0.058 13.4 3.5 0.14 12.1 0.3 2.5 1 1 0 2 2 2 0 DASH complex subunit Dad4 HAP1_N PF04849.13 AAL64171.1 - 0.063 12.5 16.0 0.092 11.9 16.0 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region HMMR_N PF15905.5 AAL64171.1 - 0.079 12.4 14.9 0.12 11.9 14.9 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal YabA PF06156.13 AAL64171.1 - 0.081 13.6 13.0 0.83 10.3 5.4 2.3 1 1 1 2 2 2 0 Initiation control protein YabA Rootletin PF15035.6 AAL64171.1 - 0.097 12.7 17.4 1.1 9.2 17.4 2.1 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion GIT_CC PF16559.5 AAL64171.1 - 0.1 12.5 17.1 0.68 9.8 0.0 3.5 1 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Taxilin PF09728.9 AAL64171.1 - 0.11 11.7 18.2 0.15 11.2 18.2 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein DUF2009 PF09418.10 AAL64171.1 - 0.11 11.5 2.1 0.15 11.1 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) GIDA_assoc PF13932.6 AAL64171.1 - 0.15 12.3 5.9 0.21 11.7 5.9 1.2 1 0 0 1 1 1 0 GidA associated domain CCDC144C PF14915.6 AAL64171.1 - 0.15 11.1 17.3 0.31 10.1 17.3 1.4 1 1 0 1 1 1 0 CCDC144C protein coiled-coil region Mod_r PF07200.13 AAL64171.1 - 0.17 11.9 21.3 0.32 11.1 5.6 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein XLF PF09302.11 AAL64171.1 - 0.17 12.0 6.8 0.088 13.0 2.7 2.1 1 1 1 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component GOLGA2L5 PF15070.6 AAL64171.1 - 0.18 10.4 18.7 0.022 13.5 5.4 2.2 1 1 1 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 ALIX_LYPXL_bnd PF13949.6 AAL64171.1 - 0.18 11.1 16.3 0.15 11.3 5.8 2.0 1 1 0 1 1 1 0 ALIX V-shaped domain binding to HIV PspA_IM30 PF04012.12 AAL64171.1 - 0.19 11.3 28.7 0.28 10.7 28.7 1.2 1 0 0 1 1 1 0 PspA/IM30 family Myosin_tail_1 PF01576.19 AAL64171.1 - 0.2 9.4 16.2 0.27 9.0 16.2 1.1 1 0 0 1 1 1 0 Myosin tail DUF885 PF05960.11 AAL64171.1 - 0.21 11.2 8.3 0.36 10.4 8.3 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) PIN_8 PF18476.1 AAL64171.1 - 0.21 11.4 5.2 0.3 10.9 5.2 1.2 1 0 0 1 1 1 0 PIN like domain V_ATPase_I PF01496.19 AAL64171.1 - 0.25 9.2 4.3 0.44 8.4 4.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_23 PF13476.6 AAL64171.1 - 0.25 11.8 8.0 0.45 11.0 8.0 1.4 1 0 0 1 1 1 0 AAA domain NPV_P10 PF05531.12 AAL64171.1 - 0.26 11.8 12.7 0.43 11.1 2.5 3.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Peptidase_S46 PF10459.9 AAL64171.1 - 0.26 9.9 6.9 0.35 9.5 6.9 1.1 1 0 0 1 1 1 0 Peptidase S46 DUF4515 PF14988.6 AAL64171.1 - 0.27 11.1 18.4 0.21 11.4 4.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4515) YkyA PF10368.9 AAL64171.1 - 0.28 10.8 12.2 0.47 10.1 12.2 1.3 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein UPF0242 PF06785.11 AAL64171.1 - 0.29 11.2 19.6 0.41 10.7 6.9 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus HrpB7 PF09486.10 AAL64171.1 - 0.3 11.4 22.9 0.069 13.5 17.9 2.2 1 1 1 2 2 1 0 Bacterial type III secretion protein (HrpB7) ERM PF00769.19 AAL64171.1 - 0.32 10.8 23.9 0.57 9.9 23.9 1.3 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Golgin_A5 PF09787.9 AAL64171.1 - 0.33 10.4 18.6 0.24 10.9 6.7 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 NYD-SP28 PF14772.6 AAL64171.1 - 0.38 10.8 13.8 0.32 11.1 5.6 2.7 1 1 1 2 2 2 0 Sperm tail DUF948 PF06103.11 AAL64171.1 - 0.39 11.0 8.6 3.1 8.1 1.7 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) MAD PF05557.13 AAL64171.1 - 0.39 9.0 16.2 0.53 8.6 16.2 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Seryl_tRNA_N PF02403.22 AAL64171.1 - 0.39 11.0 17.3 2.5 8.4 6.4 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Phage_GP20 PF06810.11 AAL64171.1 - 0.42 10.4 10.9 1.7 8.5 7.9 2.5 1 1 1 2 2 2 0 Phage minor structural protein GP20 Syntaxin PF00804.25 AAL64171.1 - 0.44 10.2 12.1 0.39 10.4 8.3 1.8 1 1 1 2 2 2 0 Syntaxin Mt_ATP-synt_D PF05873.12 AAL64171.1 - 0.45 10.4 1.9 0.76 9.6 1.9 1.3 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) DUF1682 PF07946.14 AAL64171.1 - 0.47 9.6 8.5 0.69 9.1 8.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) TMPIT PF07851.13 AAL64171.1 - 0.5 9.6 8.7 1.1 8.4 8.6 1.6 1 1 0 1 1 1 0 TMPIT-like protein DUF4795 PF16043.5 AAL64171.1 - 0.58 9.7 14.7 1.1 8.9 14.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Exonuc_VII_L PF02601.15 AAL64171.1 - 0.61 9.6 13.6 0.85 9.1 13.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Fungal_TACC PF12709.7 AAL64171.1 - 0.63 10.5 9.5 3.4 8.2 0.4 3.5 1 1 1 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins SlyX PF04102.12 AAL64171.1 - 0.63 10.7 25.3 7.6 7.2 7.9 3.9 2 1 2 4 4 3 0 SlyX DUF4472 PF14739.6 AAL64171.1 - 0.65 10.7 15.3 2.1 9.1 9.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) Jnk-SapK_ap_N PF09744.9 AAL64171.1 - 0.67 10.2 18.6 1.2 9.3 17.1 1.8 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF1664 PF07889.12 AAL64171.1 - 0.68 10.0 14.4 0.096 12.7 1.7 2.7 2 1 1 3 3 2 0 Protein of unknown function (DUF1664) Not3 PF04065.15 AAL64171.1 - 0.69 9.3 10.5 2.4 7.6 7.4 2.1 1 1 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component SOGA PF11365.8 AAL64171.1 - 0.73 11.0 11.6 0.1 13.8 2.7 2.3 1 1 1 2 2 2 0 Protein SOGA EST1 PF10374.9 AAL64171.1 - 0.74 10.4 2.8 1.9 9.2 2.8 1.7 1 1 0 1 1 1 0 Telomerase activating protein Est1 PI3K_P85_iSH2 PF16454.5 AAL64171.1 - 0.74 9.4 13.2 0.43 10.2 6.8 2.5 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF812 PF05667.11 AAL64171.1 - 0.75 8.6 17.1 2.1 7.2 17.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DivIC PF04977.15 AAL64171.1 - 0.84 9.4 26.0 0.33 10.8 5.3 3.8 1 1 2 3 3 3 0 Septum formation initiator ZapB PF06005.12 AAL64171.1 - 0.95 10.0 26.9 1.9 9.0 8.1 3.2 1 1 1 2 2 2 0 Cell division protein ZapB COG2 PF06148.11 AAL64171.1 - 1 9.4 11.8 2.1 8.5 2.0 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 zf-C4H2 PF10146.9 AAL64171.1 - 1.1 9.5 8.7 1.5 9.1 8.7 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein Spc29 PF17082.5 AAL64171.1 - 1.1 9.0 6.9 0.75 9.6 2.0 2.0 1 1 1 2 2 2 0 Spindle Pole Component 29 Occludin_ELL PF07303.13 AAL64171.1 - 1.3 9.8 7.4 9.4 7.0 1.1 2.4 1 1 1 2 2 2 0 Occludin homology domain COG5 PF10392.9 AAL64171.1 - 1.5 9.0 13.3 1.4 9.1 11.1 1.9 1 1 0 1 1 1 0 Golgi transport complex subunit 5 Rab5-bind PF09311.11 AAL64171.1 - 1.7 7.9 17.1 22 4.3 16.6 2.0 1 1 0 1 1 1 0 Rabaptin-like protein Sec34 PF04136.15 AAL64171.1 - 1.8 8.4 14.4 0.99 9.3 3.9 2.4 1 1 1 2 2 2 0 Sec34-like family HSCB_C PF07743.13 AAL64171.1 - 1.8 9.1 18.5 0.12 12.8 4.8 3.1 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain FH2 PF02181.23 AAL64171.1 - 2 7.4 8.4 7.6 5.5 8.3 1.8 1 1 0 1 1 1 0 Formin Homology 2 Domain Bap31_Bap29_C PF18035.1 AAL64171.1 - 2.5 8.2 12.6 0.33 11.0 6.1 2.8 2 2 0 2 2 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain Syntaxin-6_N PF09177.11 AAL64171.1 - 2.5 8.7 10.3 2.6 8.7 7.4 2.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Fib_alpha PF08702.10 AAL64171.1 - 2.6 8.2 12.4 2.7 8.2 6.0 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TMCO5 PF14992.6 AAL64171.1 - 2.6 7.6 11.4 6.2 6.3 2.2 2.0 1 1 1 2 2 2 0 TMCO5 family PRKG1_interact PF15898.5 AAL64171.1 - 2.7 8.9 17.5 2.9 8.8 5.0 2.3 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain JIP_LZII PF16471.5 AAL64171.1 - 2.9 8.1 11.7 8.7 6.6 0.8 3.1 1 1 2 3 3 3 0 JNK-interacting protein leucine zipper II DUF4200 PF13863.6 AAL64171.1 - 2.9 8.3 18.3 16 6.0 16.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF2730 PF10805.8 AAL64171.1 - 2.9 8.0 7.4 15 5.8 0.2 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) CdvA PF18822.1 AAL64171.1 - 3.2 7.6 12.1 9.1 6.1 4.0 2.7 1 1 1 2 2 2 0 CdvA-like coiled-coil domain SYCE1 PF15233.6 AAL64171.1 - 3.4 7.7 16.4 5.9 6.9 16.4 1.3 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 DUF16 PF01519.16 AAL64171.1 - 4.1 8.0 10.2 81 3.8 10.1 2.4 1 1 0 1 1 1 0 Protein of unknown function DUF16 Nsp1_C PF05064.13 AAL64171.1 - 4.2 7.2 13.1 0.93 9.3 2.6 2.3 1 1 1 2 2 2 0 Nsp1-like C-terminal region SKA1 PF07160.12 AAL64171.1 - 4.4 7.1 10.4 14 5.5 10.4 1.7 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 1 FlgN PF05130.12 AAL64171.1 - 4.4 7.8 23.8 13 6.3 17.7 2.0 1 1 0 1 1 1 0 FlgN protein OmpH PF03938.14 AAL64171.1 - 4.5 7.6 26.4 6.3e+02 0.6 27.2 2.2 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) FlxA PF14282.6 AAL64171.1 - 4.5 7.3 29.7 0.19 11.7 7.8 2.3 1 1 1 2 2 2 0 FlxA-like protein Nup54 PF13874.6 AAL64171.1 - 4.5 7.4 20.9 3.2 7.9 11.9 2.2 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 YlqD PF11068.8 AAL64171.1 - 4.7 7.6 22.9 7.5e+03 -2.8 22.9 2.3 1 1 0 1 1 0 0 YlqD protein Uso1_p115_C PF04871.13 AAL64171.1 - 4.8 7.6 22.3 1.8e+02 2.5 22.4 2.3 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Csm1_N PF18504.1 AAL64171.1 - 5.5 7.4 19.1 3.5 8.0 2.1 4.1 1 1 4 5 5 5 0 Csm1 N-terminal domain Leu_zip PF15294.6 AAL64171.1 - 5.7 6.4 14.3 23 4.4 14.4 1.7 1 1 0 1 1 1 0 Leucine zipper CENP-H PF05837.12 AAL64171.1 - 5.8 7.4 22.9 0.47 10.9 10.9 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) MPS2 PF17060.5 AAL64171.1 - 6.1 6.0 9.2 7 5.8 8.2 1.5 1 1 0 1 1 1 0 Monopolar spindle protein 2 RasGAP_C PF03836.15 AAL64171.1 - 6.5 6.9 11.4 4.9 7.3 1.6 2.2 1 1 1 2 2 2 0 RasGAP C-terminus DUF2203 PF09969.9 AAL64171.1 - 6.8 7.4 13.9 11 6.7 4.2 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) FliJ PF02050.16 AAL64171.1 - 7.4 6.8 27.6 8.2 6.7 11.7 2.3 1 1 1 2 2 2 0 Flagellar FliJ protein Spectrin PF00435.21 AAL64171.1 - 7.5 7.1 17.9 4.3 7.9 4.8 2.2 1 1 1 2 2 2 0 Spectrin repeat CDC37_N PF03234.14 AAL64171.1 - 8 7.4 8.8 42 5.1 8.8 1.9 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding CorA PF01544.18 AAL64171.1 - 9.3 5.5 13.2 3.7 6.8 10.3 1.8 2 0 0 2 2 1 0 CorA-like Mg2+ transporter protein GIDE PF12483.8 AAL64176.1 - 0.17 11.2 0.0 0.35 10.2 0.0 1.4 1 0 0 1 1 1 0 E3 Ubiquitin ligase DUF1967 PF09269.11 AAL64176.1 - 0.21 11.6 0.0 0.84 9.6 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) DUF4179 PF13786.6 AAL64177.1 - 0.061 13.8 4.6 0.3 11.6 3.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) SnoaL_4 PF13577.6 AAL64177.1 - 0.084 13.0 0.0 1.7 8.8 0.0 2.0 2 0 0 2 2 2 0 SnoaL-like domain Nre_N PF04894.12 AAL64180.1 - 9.5e-85 284.7 0.0 1.2e-84 284.4 0.0 1.1 1 0 0 1 1 1 1 Archaeal Nre, N-terminal Nre_C PF04895.12 AAL64180.1 - 7.4e-17 61.3 0.3 1.3e-16 60.5 0.3 1.3 1 0 0 1 1 1 1 Archaeal Nre, C-terminal Cys_Met_Meta_PP PF01053.20 AAL64181.1 - 5.7e-112 374.0 0.0 6.5e-112 373.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 AAL64181.1 - 0.0024 16.9 0.0 0.0032 16.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V GDC-P PF02347.16 AAL64181.1 - 0.16 10.8 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein TrkA_C PF02080.21 AAL64182.1 - 1.4e-08 34.4 0.6 8.1e-08 32.0 0.0 2.6 3 1 1 4 4 4 1 TrkA-C domain TrkA_N PF02254.18 AAL64182.1 - 1.6e-05 25.1 0.9 1.6e-05 25.1 0.9 1.7 2 0 0 2 2 2 1 TrkA-N domain SIS PF01380.22 AAL64182.1 - 0.00055 19.8 0.6 0.024 14.5 0.3 2.3 2 1 0 2 2 2 1 SIS domain DUF166 PF02593.14 AAL64182.1 - 0.0084 15.7 0.2 0.015 14.8 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function Response_reg PF00072.24 AAL64182.1 - 0.052 13.7 0.9 2.7 8.2 0.9 2.6 1 1 0 1 1 1 0 Response regulator receiver domain DUF2590 PF10761.9 AAL64182.1 - 0.07 13.3 0.2 0.89 9.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2590) MS_channel PF00924.18 AAL64183.1 - 3.7e-09 36.4 0.8 6.1e-09 35.7 0.0 1.7 2 0 0 2 2 2 1 Mechanosensitive ion channel Phage_holin_2_1 PF04971.12 AAL64183.1 - 0.029 14.4 1.2 0.062 13.3 1.2 1.5 1 0 0 1 1 1 0 Bacteriophage P21 holin S 7tm_3 PF00003.22 AAL64183.1 - 0.14 11.8 7.6 0.18 11.5 7.6 1.1 1 0 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR TraQ PF09679.10 AAL64183.1 - 2.1 8.3 5.1 0.99 9.4 0.6 2.5 2 1 1 3 3 3 0 Type-F conjugative transfer system pilin chaperone (TraQ) DUF2981 PF11200.8 AAL64183.1 - 2.8 7.6 4.0 4.5 6.9 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) DUF4131 PF13567.6 AAL64183.1 - 4.4 6.9 9.2 2.6 7.7 5.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Glycophorin_A PF01102.18 AAL64183.1 - 5.2 7.3 7.1 0.31 11.3 1.2 1.8 2 0 0 2 2 2 0 Glycophorin A PPDK_N PF01326.19 AAL64184.1 - 1.7e-113 379.3 0.0 2.6e-113 378.6 0.0 1.3 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers_C PF02896.18 AAL64184.1 - 4.1e-75 252.6 0.0 6.6e-75 251.9 0.0 1.3 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilizers PF00391.23 AAL64184.1 - 1e-28 98.8 0.2 2.7e-28 97.5 0.2 1.8 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain Radical_SAM PF04055.21 AAL64186.1 - 9.8e-23 81.4 0.1 3.6e-22 79.5 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily B12-binding PF02310.19 AAL64186.1 - 6.6e-07 29.4 0.0 1.5e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 B12 binding domain Peptidase_M22 PF00814.25 AAL64189.1 - 8.1e-78 261.8 0.1 1e-77 261.5 0.1 1.0 1 0 0 1 1 1 1 Glycoprotease family Ribosomal_S27 PF01599.19 AAL64190.1 - 4.1e-10 39.6 0.4 5e-10 39.4 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S27a OrfB_Zn_ribbon PF07282.11 AAL64190.1 - 0.00019 21.2 0.2 0.00021 21.1 0.2 1.1 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Zn_Tnp_IS1595 PF12760.7 AAL64190.1 - 0.0016 18.4 3.1 0.0023 17.9 3.1 1.2 1 0 0 1 1 1 1 Transposase zinc-ribbon domain DUF2387 PF09526.10 AAL64190.1 - 0.0068 16.5 0.8 0.011 15.9 0.8 1.3 1 0 0 1 1 1 1 Probable metal-binding protein (DUF2387) RNA_POL_M_15KD PF02150.16 AAL64190.1 - 0.0089 15.9 0.5 0.023 14.6 0.5 1.6 1 1 0 1 1 1 1 RNA polymerases M/15 Kd subunit DUF1451 PF07295.11 AAL64190.1 - 0.011 15.8 1.4 0.014 15.4 1.3 1.3 1 1 0 1 1 1 0 Zinc-ribbon containing domain Nudix_N_2 PF14803.6 AAL64190.1 - 0.021 14.7 3.7 0.091 12.7 3.7 1.9 1 1 0 1 1 1 0 Nudix N-terminal Lar_restr_allev PF14354.6 AAL64190.1 - 0.032 14.6 2.2 0.053 13.9 2.2 1.4 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf-NADH-PPase PF09297.11 AAL64190.1 - 0.034 13.8 3.6 0.56 9.9 0.0 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Ribosomal_L37ae PF01780.19 AAL64190.1 - 0.036 14.2 0.6 0.049 13.7 0.6 1.2 1 0 0 1 1 1 0 Ribosomal L37ae protein family PriA_CRR PF18319.1 AAL64190.1 - 0.065 13.2 1.5 0.28 11.2 1.5 2.1 1 1 0 1 1 1 0 PriA DNA helicase Cys-rich region (CRR) domain HalOD2 PF18547.1 AAL64190.1 - 0.07 13.0 1.8 0.81 9.6 0.6 2.1 2 0 0 2 2 2 0 Halobacterial output domain 2 TF_Zn_Ribbon PF08271.12 AAL64190.1 - 0.11 12.1 1.5 0.67 9.5 0.0 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding zf-RRN7 PF11781.8 AAL64190.1 - 0.11 12.2 3.3 0.87 9.3 0.0 2.4 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-ribbon_3 PF13248.6 AAL64190.1 - 0.11 11.9 5.5 0.34 10.4 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf_C2H2_10 PF18414.1 AAL64190.1 - 0.12 12.0 3.6 4.9 6.8 0.5 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger zinc_ribbon_2 PF13240.6 AAL64190.1 - 0.15 11.8 6.6 0.27 11.0 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf_UBZ PF18439.1 AAL64190.1 - 0.31 10.7 2.4 0.59 9.8 0.1 2.1 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger ADK_lid PF05191.14 AAL64190.1 - 0.57 10.2 4.7 2.4 8.2 4.7 2.0 1 1 0 1 1 1 0 Adenylate kinase, active site lid Zn-ribbon_8 PF09723.10 AAL64190.1 - 0.59 10.3 4.3 1.6 8.9 0.3 2.2 1 1 0 1 1 1 0 Zinc ribbon domain YhfH PF14149.6 AAL64190.1 - 2.2 8.3 6.9 0.56 10.2 0.6 2.2 1 1 1 2 2 2 0 YhfH-like protein Ribosomal_S24e PF01282.19 AAL64191.1 - 4.7e-20 71.3 0.0 4.7e-20 71.3 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S24e MazG-like PF12643.7 AAL64191.1 - 0.0041 17.3 0.7 0.036 14.3 0.2 2.3 2 1 0 2 2 2 1 MazG-like family PsiE PF06146.12 AAL64192.1 - 2.8e-13 50.0 7.8 2.8e-13 50.0 7.8 2.0 2 1 1 3 3 3 1 Phosphate-starvation-inducible E Ninjurin PF04923.12 AAL64192.1 - 5 7.1 9.2 9.5 6.2 4.4 2.1 1 1 1 2 2 2 0 Ninjurin DUF805 PF05656.14 AAL64192.1 - 9.1 6.8 7.7 73 3.9 7.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF805) Radical_SAM PF04055.21 AAL64193.1 - 9.2e-13 48.9 0.0 2.8e-12 47.3 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily B12-binding PF02310.19 AAL64193.1 - 0.036 14.1 0.0 0.14 12.2 0.0 2.1 2 0 0 2 2 2 0 B12 binding domain CPBP PF02517.16 AAL64194.1 - 3.7e-10 40.1 1.0 3.7e-10 40.1 1.0 1.9 1 1 1 2 2 2 1 CPBP intramembrane metalloprotease CorA PF01544.18 AAL64195.1 - 7.9e-17 61.5 3.2 5.4e-16 58.8 3.2 1.9 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Ubiq_cyt_C_chap PF03981.12 AAL64195.1 - 0.18 11.9 2.0 0.34 11.0 0.1 2.0 1 1 1 2 2 2 0 Ubiquinol-cytochrome C chaperone OCD_Mu_crystall PF02423.15 AAL64196.1 - 4e-35 121.3 0.1 7.5e-35 120.4 0.1 1.4 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 AAL64196.1 - 3.4e-07 30.4 0.0 5.6e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 AAL64196.1 - 0.00035 21.1 0.0 0.00064 20.3 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 AAL64196.1 - 0.012 14.9 0.2 0.019 14.2 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GFO_IDH_MocA PF01408.22 AAL64196.1 - 0.035 14.9 0.0 0.11 13.3 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold 2-Hacid_dh_C PF02826.19 AAL64196.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 AAL64196.1 - 0.11 11.8 0.3 0.26 10.6 0.1 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ResIII PF04851.15 AAL64197.1 - 1.4e-29 103.3 0.0 1.2e-28 100.3 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 AAL64197.1 - 1.3e-17 64.1 0.0 4e-17 62.5 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain XPB_DRD PF18458.1 AAL64197.1 - 1.1e-15 57.2 0.2 3e-15 55.8 0.2 1.8 1 0 0 1 1 1 1 Xeroderma pigmentosum group B helicase damage recognition domain ERCC3_RAD25_C PF16203.5 AAL64197.1 - 8.8e-14 51.3 0.0 1.3e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 AAL64197.1 - 6.6e-12 45.5 0.0 2.1e-11 43.9 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase IstB_IS21 PF01695.17 AAL64197.1 - 0.02 14.6 0.1 0.071 12.8 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_22 PF13401.6 AAL64197.1 - 0.17 12.1 0.0 3.8 7.8 0.0 2.8 2 1 0 2 2 2 0 AAA domain DUF790 PF05626.11 AAL64198.1 - 6.2e-102 341.2 1.2 7e-102 341.1 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF790) HTH_10 PF04967.12 AAL64199.1 - 1.6e-17 63.0 0.1 2.9e-17 62.2 0.1 1.5 1 0 0 1 1 1 1 HTH DNA binding domain Sigma70_r4 PF04545.16 AAL64199.1 - 2.1e-05 24.0 0.1 3.7e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 AAL64199.1 - 0.00043 19.9 1.3 0.0005 19.7 0.2 1.7 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_Crp_2 PF13545.6 AAL64199.1 - 0.0082 16.1 0.0 0.29 11.1 0.0 2.7 3 0 0 3 3 3 1 Crp-like helix-turn-helix domain MarR PF01047.22 AAL64199.1 - 0.015 15.2 0.1 0.11 12.5 0.0 2.2 2 1 0 2 2 2 0 MarR family MarR_2 PF12802.7 AAL64199.1 - 0.032 14.1 0.2 0.16 11.9 0.0 2.0 2 0 0 2 2 2 0 MarR family HTH_24 PF13412.6 AAL64199.1 - 0.067 12.8 0.1 0.26 10.9 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_AraC PF00165.23 AAL64199.1 - 0.16 12.1 0.0 1.3 9.3 0.0 2.1 1 1 1 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_AsnC-type PF13404.6 AAL64199.1 - 0.28 11.1 2.0 0.57 10.1 0.4 2.1 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Fer4_10 PF13237.6 AAL64200.1 - 3e-10 40.0 5.3 4.8e-10 39.4 5.3 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 AAL64200.1 - 3.6e-10 39.8 9.3 4.5e-10 39.5 9.3 1.1 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 AAL64200.1 - 1.6e-09 37.2 16.8 5.3e-09 35.5 2.8 2.4 2 1 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 AAL64200.1 - 3.3e-09 36.4 14.5 7.1e-09 35.4 2.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 AAL64200.1 - 4.5e-09 36.7 9.2 1.8e-08 34.9 9.3 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAL64200.1 - 1.7e-08 35.3 7.1 9.5e-05 23.3 2.3 2.1 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_2 PF12797.7 AAL64200.1 - 3.1e-07 30.1 10.3 1.1e-06 28.3 2.9 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_15 PF13459.6 AAL64200.1 - 9.9e-07 29.4 10.1 5.7e-05 23.8 10.1 2.4 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_9 PF13187.6 AAL64200.1 - 3.5e-06 27.1 10.0 9e-06 25.8 10.2 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_4 PF12800.7 AAL64200.1 - 2.2e-05 24.6 14.5 7.6e-05 22.9 4.3 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_3 PF12798.7 AAL64200.1 - 0.0007 20.4 17.9 0.014 16.3 6.3 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_13 PF13370.6 AAL64200.1 - 0.00072 20.0 13.6 0.039 14.5 13.6 2.4 1 1 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_11 PF13247.6 AAL64200.1 - 0.0014 18.7 4.6 0.0043 17.2 4.5 1.7 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 AAL64200.1 - 0.0017 18.8 11.3 0.0056 17.1 2.2 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAL64200.1 - 0.01 16.3 10.0 0.025 15.1 2.9 2.3 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 AAL64200.1 - 0.018 15.9 3.2 0.17 12.8 0.6 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 AAL64200.1 - 1.8 8.8 12.6 0.64 10.2 3.0 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Radical_SAM PF04055.21 AAL64201.1 - 2.7e-17 63.7 0.1 1.3e-16 61.4 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 AAL64201.1 - 4.8e-05 23.6 0.0 8.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain DUF3795 PF12675.7 AAL64201.1 - 4.3 7.8 5.5 0.33 11.4 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3795) TK PF00265.18 AAL64203.1 - 7.6e-48 162.7 0.0 8.4e-48 162.6 0.0 1.0 1 0 0 1 1 1 1 Thymidine kinase zf-C4_ClpX PF06689.13 AAL64203.1 - 0.044 13.7 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 ClpX C4-type zinc finger AAA_14 PF13173.6 AAL64203.1 - 0.077 13.0 0.0 0.13 12.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain DUF401 PF04165.12 AAL64204.1 - 3.4e-47 161.6 21.5 4.1e-47 161.4 21.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF401) Ribosomal_S30 PF04758.14 AAL64205.1 - 2.3e-11 43.7 1.9 2.8e-11 43.4 1.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S30 TrmO PF01980.16 AAL64206.1 - 3.7e-31 107.8 0.0 4.3e-31 107.6 0.0 1.0 1 0 0 1 1 1 1 tRNA-methyltransferase O CitMHS PF03600.16 AAL64207.1 - 2.4e-26 92.7 40.2 2.4e-26 92.7 40.2 2.0 1 1 1 2 2 2 1 Citrate transporter Na_sulph_symp PF00939.19 AAL64207.1 - 5.4e-05 22.4 25.2 0.003 16.7 3.9 3.4 1 1 2 3 3 3 3 Sodium:sulfate symporter transmembrane region Trp_syntA PF00290.20 AAL64208.1 - 4.1e-19 68.4 0.0 5.3e-11 41.9 0.0 2.0 2 0 0 2 2 2 2 Tryptophan synthase alpha chain NanE PF04131.14 AAL64208.1 - 5.1e-05 22.5 0.0 6.6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase ThiG PF05690.14 AAL64208.1 - 0.00021 20.7 0.0 0.00026 20.4 0.0 1.1 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG IGPS PF00218.21 AAL64208.1 - 0.0045 16.2 0.0 0.0068 15.6 0.0 1.1 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase IMPDH PF00478.25 AAL64208.1 - 0.0092 15.0 0.0 0.012 14.6 0.0 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 AAL64208.1 - 0.011 15.2 0.0 0.014 14.8 0.0 1.1 1 0 0 1 1 1 0 Histidine biosynthesis protein FMN_dh PF01070.18 AAL64208.1 - 0.091 11.8 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 FMN-dependent dehydrogenase GATase PF00117.28 AAL64209.1 - 2.4e-49 167.7 0.0 2.9e-49 167.4 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AAL64209.1 - 3.4e-13 49.9 0.3 2.1e-12 47.3 0.1 2.2 1 1 1 2 2 2 1 Peptidase C26 Chorismate_bind PF00425.18 AAL64210.1 - 1.3e-91 306.7 0.0 1.6e-91 306.4 0.0 1.1 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 AAL64210.1 - 9.6e-05 22.6 0.1 0.01 16.0 0.1 2.7 1 1 0 1 1 1 1 Anthranilate synthase component I, N terminal region DUF4073 PF13285.6 AAL64210.1 - 0.075 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4073) Glycos_transf_3 PF00591.21 AAL64211.1 - 1.1e-77 261.1 1.2 1.4e-77 260.7 1.2 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 AAL64211.1 - 4.5e-15 55.2 0.7 1.2e-14 53.8 0.7 1.8 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain PALP PF00291.25 AAL64212.1 - 4.2e-47 161.0 1.3 5.2e-47 160.7 1.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme AMP-binding PF00501.28 AAL64213.1 - 1e-73 248.3 0.0 1.4e-73 247.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ABC_tran PF00005.27 AAL64213.1 - 1.4e-22 80.7 0.0 3.3e-22 79.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAL64213.1 - 8.1e-13 48.8 1.3 6.6e-06 26.1 0.1 2.4 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAL64213.1 - 4.1e-05 23.1 0.0 0.00012 21.6 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 AAL64213.1 - 0.00044 20.1 0.1 0.0076 16.0 0.0 2.2 1 1 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 AAL64213.1 - 0.001 19.6 0.3 0.0025 18.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 AAL64213.1 - 0.0049 16.8 0.2 1.3 8.9 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.6 AAL64213.1 - 0.0053 16.5 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 AAL64213.1 - 0.014 15.1 0.2 0.033 13.9 0.2 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 AAL64213.1 - 0.016 15.6 0.0 0.026 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_PrkA PF08298.11 AAL64213.1 - 0.021 13.8 0.0 0.04 12.8 0.0 1.4 1 0 0 1 1 1 0 PrkA AAA domain AAA_27 PF13514.6 AAL64213.1 - 0.031 13.9 0.1 0.06 12.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 AAL64213.1 - 0.063 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase RNA_helicase PF00910.22 AAL64213.1 - 0.12 12.8 0.3 4 7.9 0.1 2.4 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 AAL64213.1 - 0.14 12.6 0.1 0.67 10.4 0.0 2.1 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 AAL64213.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain ABC_tran PF00005.27 AAL64214.1 - 1.4e-29 103.4 0.0 1.8e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAL64214.1 - 6.6e-06 26.1 0.1 0.00036 20.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system BCA_ABC_TP_C PF12399.8 AAL64214.1 - 2.8e-05 23.9 0.0 6.6e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_23 PF13476.6 AAL64214.1 - 6e-05 23.6 0.1 9.3e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AAL64214.1 - 0.0012 18.8 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 AAL64214.1 - 0.0022 17.7 0.1 0.0072 16.0 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_15 PF13175.6 AAL64214.1 - 0.0036 17.1 0.0 0.0067 16.2 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_27 PF13514.6 AAL64214.1 - 0.0066 16.1 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 AAL64214.1 - 0.01 15.5 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA PF00004.29 AAL64214.1 - 0.012 16.0 0.4 4.2 7.8 0.1 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 AAL64214.1 - 0.017 14.8 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 AAL64214.1 - 0.019 14.4 0.1 0.085 12.3 0.0 1.8 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain U6-snRNA_bdg PF10596.9 AAL64214.1 - 0.025 14.6 0.1 0.088 12.8 0.0 1.8 2 0 0 2 2 2 0 U6-snRNA interacting domain of PrP8 AAA_13 PF13166.6 AAL64214.1 - 0.035 12.8 0.1 0.073 11.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 AAL64214.1 - 0.049 14.0 0.1 0.075 13.4 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 AAL64214.1 - 0.053 13.6 0.3 0.12 12.5 0.3 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.6 AAL64214.1 - 0.059 12.9 0.1 0.59 9.7 0.1 2.2 2 1 0 2 2 2 0 AAA domain Rad17 PF03215.15 AAL64214.1 - 0.068 13.1 0.0 0.38 10.7 0.0 1.9 1 1 0 2 2 2 0 Rad17 P-loop domain AAA_28 PF13521.6 AAL64214.1 - 0.072 13.3 0.1 1.5 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 AAL64214.1 - 0.08 11.7 1.2 0.95 8.2 0.1 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class cobW PF02492.19 AAL64214.1 - 0.1 12.2 0.1 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 AAL64214.1 - 0.11 11.5 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein TniB PF05621.11 AAL64214.1 - 0.14 11.5 0.4 15 4.9 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_22 PF13401.6 AAL64214.1 - 0.15 12.4 0.2 0.42 10.9 0.1 1.8 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 AAL64214.1 - 0.17 11.1 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AMP-binding PF00501.28 AAL64215.1 - 2.7e-43 148.1 0.1 3.9e-42 144.3 0.1 2.1 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAL64215.1 - 2.7e-09 37.9 0.2 6.3e-09 36.7 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CoA_transf_3 PF02515.17 AAL64216.1 - 3.7e-49 167.8 0.0 4.9e-49 167.4 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III 4HBT_2 PF13279.6 AAL64217.1 - 4.6e-06 27.1 0.0 5.6e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 AAL64217.1 - 0.00012 22.3 0.1 0.0002 21.7 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily CobW_C PF07683.14 AAL64217.1 - 0.02 14.8 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain Thiolase_N PF00108.23 AAL64218.1 - 1.3e-22 80.4 4.3 4.2e-22 78.8 4.3 1.8 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 AAL64218.1 - 1.2e-08 34.6 0.1 2.9e-08 33.4 0.1 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 AAL64218.1 - 0.00058 19.5 3.6 0.0015 18.2 3.3 1.6 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 AAL64218.1 - 0.1 12.7 5.6 1.2 9.2 0.0 3.8 4 0 0 4 4 4 0 Beta-ketoacyl synthase, C-terminal domain DUF35_N PF12172.8 AAL64219.1 - 4e-11 42.6 0.2 6.1e-11 42.0 0.2 1.2 1 0 0 1 1 1 1 Rubredoxin-like zinc ribbon domain (DUF35_N) OB_aCoA_assoc PF01796.17 AAL64219.1 - 0.0014 18.6 0.3 0.002 18.1 0.3 1.2 1 0 0 1 1 1 1 DUF35 OB-fold domain, acyl-CoA-associated zf-CCCH_6 PF18585.1 AAL64219.1 - 0.021 14.7 0.6 0.03 14.2 0.6 1.3 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 TackOD1 PF18551.1 AAL64219.1 - 0.037 13.7 0.3 0.047 13.4 0.3 1.1 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 NRDD PF13597.6 AAL64219.1 - 0.04 12.7 0.9 0.051 12.3 0.9 1.1 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase Mcm10 PF09332.11 AAL64219.1 - 0.14 11.5 0.2 0.18 11.2 0.2 1.1 1 0 0 1 1 1 0 Mcm10 replication factor A2L_zn_ribbon PF08792.10 AAL64219.1 - 0.36 10.6 2.5 15 5.5 0.2 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain AMP-binding PF00501.28 AAL64220.1 - 3.4e-91 306.0 0.0 4.4e-91 305.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAL64220.1 - 1.5e-20 73.9 3.0 3e-20 73.0 3.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 AAL64220.1 - 5.9e-19 67.7 2.5 5.9e-19 67.7 2.5 2.1 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus Acyl-CoA_dh_1 PF00441.24 AAL64221.1 - 1.6e-51 174.4 1.0 2.8e-51 173.7 1.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 AAL64221.1 - 4.9e-26 91.6 0.0 1.2e-25 90.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 AAL64221.1 - 1.6e-21 76.3 0.0 2.9e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 AAL64221.1 - 8.9e-21 74.6 0.3 1.6e-20 73.8 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB PF03241.13 AAL64221.1 - 0.00041 19.5 0.1 0.001 18.2 0.1 1.6 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase C terminal FAD_binding_5 PF00941.21 AAL64222.1 - 1.7e-42 145.1 0.0 2.6e-42 144.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Fer2_2 PF01799.20 AAL64222.1 - 1.6e-22 79.3 0.1 3.9e-22 78.1 0.1 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 AAL64222.1 - 2.9e-06 27.1 0.1 7.7e-06 25.8 0.1 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 AAL64222.1 - 0.0013 18.7 0.1 0.0028 17.6 0.1 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain CO_deh_flav_C PF03450.17 AAL64222.1 - 0.044 14.0 0.0 0.25 11.5 0.0 2.3 3 0 0 3 3 3 0 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C2 PF02738.18 AAL64223.1 - 1.2e-129 433.3 0.0 1.6e-129 432.9 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 AAL64223.1 - 8.2e-15 55.1 0.0 1.7e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain ECH_1 PF00378.20 AAL64224.1 - 2.9e-53 180.8 0.0 3.3e-53 180.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AAL64224.1 - 3.6e-27 95.7 0.0 7.5e-26 91.4 0.1 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Aldedh PF00171.22 AAL64225.1 - 5.4e-168 559.3 0.1 6.2e-168 559.1 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AMP-binding PF00501.28 AAL64226.1 - 6.3e-72 242.5 0.0 8.3e-72 242.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAL64226.1 - 3.5e-22 79.2 0.6 8.5e-22 77.9 0.6 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 AAL64226.1 - 1.4e-09 37.7 0.5 1.4e-09 37.7 0.5 2.0 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AcrZ PF10766.9 AAL64226.1 - 0.19 11.3 0.7 0.45 10.1 0.7 1.5 1 0 0 1 1 1 0 Multidrug efflux pump-associated protein AcrZ Thiolase_N PF00108.23 AAL64230.1 - 0.015 14.7 0.3 0.035 13.5 0.3 1.5 1 1 0 1 1 1 0 Thiolase, N-terminal domain Thiolase_C PF02803.18 AAL64230.1 - 0.15 11.7 0.0 0.37 10.4 0.0 1.6 1 0 0 1 1 1 0 Thiolase, C-terminal domain Thiolase_N PF00108.23 AAL64231.1 - 9.1e-09 35.0 0.1 2.9e-07 30.1 0.1 2.2 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 AAL64231.1 - 5.3e-05 22.9 0.0 0.84 9.3 0.0 3.1 3 0 0 3 3 3 2 Thiolase, C-terminal domain ACP_syn_III PF08545.10 AAL64231.1 - 0.016 15.0 0.0 4.5 7.2 0.0 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Peptidase_M22 PF00814.25 AAL64231.1 - 0.042 13.5 0.1 0.075 12.7 0.1 1.5 1 0 0 1 1 1 0 Glycoprotease family OB_aCoA_assoc PF01796.17 AAL64232.1 - 3.7e-14 52.4 0.1 5.5e-14 51.9 0.1 1.3 1 0 0 1 1 1 1 DUF35 OB-fold domain, acyl-CoA-associated DUF35_N PF12172.8 AAL64232.1 - 2.6e-12 46.3 0.8 4.9e-12 45.5 0.8 1.4 1 0 0 1 1 1 1 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF35_N PF12172.8 AAL64233.1 - 7.3e-08 32.1 0.4 1.2e-07 31.5 0.4 1.2 1 0 0 1 1 1 1 Rubredoxin-like zinc ribbon domain (DUF35_N) OB_aCoA_assoc PF01796.17 AAL64233.1 - 3.9e-05 23.6 0.0 5.7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 DUF35 OB-fold domain, acyl-CoA-associated CpXC PF14353.6 AAL64233.1 - 0.094 12.8 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 CpXC protein zf-C2HC_2 PF13913.6 AAL64233.1 - 0.11 12.4 0.6 0.2 11.6 0.6 1.3 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Acyl-CoA_dh_1 PF00441.24 AAL64234.1 - 8e-42 143.0 0.4 1.3e-41 142.2 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 AAL64234.1 - 2.8e-28 98.8 0.1 4.9e-28 98.0 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 AAL64234.1 - 2.8e-24 85.1 0.1 5e-24 84.3 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 AAL64234.1 - 9.5e-18 64.8 0.5 3e-17 63.1 0.1 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain UPF0102 PF02021.17 AAL64235.1 - 0.005 17.1 0.2 0.0094 16.2 0.2 1.4 1 0 0 1 1 1 1 Uncharacterised protein family UPF0102 DUF4143 PF13635.6 AAL64235.1 - 0.0067 16.6 0.1 0.014 15.6 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4143) NERD PF08378.11 AAL64235.1 - 0.01 16.3 0.8 0.066 13.7 0.1 2.2 2 0 0 2 2 2 0 Nuclease-related domain Octopine_DH PF02317.17 AAL64235.1 - 0.05 13.7 0.0 0.075 13.1 0.0 1.3 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain FliG_C PF01706.16 AAL64236.1 - 0.017 15.3 0.3 0.027 14.7 0.3 1.2 1 0 0 1 1 1 0 FliG C-terminal domain Alanine_zipper PF11839.8 AAL64237.1 - 0.0013 19.0 17.3 0.0013 19.0 17.3 3.1 3 1 0 3 3 3 1 Alanine-zipper, major outer membrane lipoprotein DUF812 PF05667.11 AAL64237.1 - 0.015 14.2 23.4 0.038 12.9 23.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF812) YtxH PF12732.7 AAL64237.1 - 0.034 14.7 9.1 0.034 14.7 9.1 3.5 1 1 1 2 2 2 0 YtxH-like protein ISG65-75 PF11727.8 AAL64237.1 - 0.15 11.3 25.8 0.015 14.5 18.8 2.2 1 1 1 2 2 2 0 Invariant surface glycoprotein Sec34 PF04136.15 AAL64237.1 - 0.24 11.3 6.7 0.23 11.3 0.8 2.4 2 0 0 2 2 2 0 Sec34-like family CCDC53 PF10152.9 AAL64237.1 - 0.25 11.8 7.8 0.57 10.6 7.8 1.6 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Noelin-1 PF12308.8 AAL64237.1 - 0.27 11.3 7.2 0.34 10.9 1.3 3.0 1 1 1 3 3 3 0 Neurogenesis glycoprotein Prominin PF05478.11 AAL64237.1 - 0.29 9.0 11.3 0.53 8.2 11.3 1.3 1 1 0 1 1 1 0 Prominin DUF1687 PF07955.11 AAL64237.1 - 0.48 10.9 4.7 19 5.8 1.6 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1687) Cu PF17563.2 AAL64237.1 - 1.3 9.3 6.6 0.77 10.0 1.2 3.1 3 1 0 3 3 3 0 Cupiennin DIM PF08194.12 AAL64237.1 - 1.7 8.9 3.7 3.7 7.8 3.7 1.6 1 0 0 1 1 1 0 DIM protein CBFD_NFYB_HMF PF00808.23 AAL64237.1 - 1.8 8.9 11.2 3 8.2 9.0 2.6 2 1 0 2 2 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Synaptobrevin PF00957.21 AAL64237.1 - 1.9 8.3 8.5 0.96 9.3 3.2 2.7 2 0 0 2 2 2 0 Synaptobrevin DUF3106 PF11304.8 AAL64237.1 - 1.9 9.0 9.5 0.66 10.5 3.4 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3106) DUF1664 PF07889.12 AAL64237.1 - 2.1 8.4 11.8 7.8 6.6 2.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) T2SSM PF04612.12 AAL64237.1 - 6.5 6.8 12.5 0.95 9.5 2.5 2.7 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M FUSC PF04632.12 AAL64237.1 - 6.8 5.1 10.0 14 4.0 10.0 1.5 1 1 0 1 1 1 0 Fusaric acid resistance protein family CorA PF01544.18 AAL64237.1 - 7.7 5.7 7.5 1.6 8.0 1.6 2.0 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein ArAE_2_N PF10337.9 AAL64237.1 - 8 5.4 11.1 15 4.5 11.1 1.5 1 1 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal PRAI PF00697.22 AAL64238.1 - 1.7e-22 80.2 0.0 1.9e-22 80.0 0.0 1.0 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase AAA_14 PF13173.6 AAL64240.1 - 6.3e-16 58.6 0.0 8.1e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 AAL64240.1 - 0.00098 19.1 0.0 0.0092 15.9 0.0 1.9 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea CLP1_P PF16575.5 AAL64240.1 - 0.021 14.6 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_22 PF13401.6 AAL64240.1 - 0.028 14.7 0.0 0.14 12.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 AAL64240.1 - 0.035 14.5 0.0 0.051 14.0 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 AAL64240.1 - 0.092 13.1 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 AAL64240.1 - 0.1 13.0 0.1 0.33 11.3 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain DUF3225 PF11533.8 AAL64241.1 - 0.071 12.8 0.0 0.079 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3225) DCD PF06559.11 AAL64242.1 - 0.034 12.9 0.0 0.041 12.7 0.0 1.1 1 0 0 1 1 1 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) DUF86 PF01934.17 AAL64243.1 - 5.5e-18 65.0 0.0 8.8e-18 64.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF86 Polbeta PF18765.1 AAL64243.1 - 7.3e-13 48.4 0.0 1.4e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 AAL64243.1 - 0.029 14.7 0.0 0.06 13.6 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain Radical_SAM PF04055.21 AAL64244.1 - 3e-13 50.5 0.0 4.9e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily DUF4072 PF13284.6 AAL64244.1 - 0.064 13.7 0.0 5 7.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4072) DUF1848 PF08902.11 AAL64244.1 - 0.29 10.8 4.0 4.4 7.0 4.3 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1848) VKOR PF07884.14 AAL64247.1 - 2.4e-20 73.0 12.1 3.1e-20 72.6 12.1 1.2 1 0 0 1 1 1 1 Vitamin K epoxide reductase family DUF973 PF06157.11 AAL64248.1 - 2.4e-05 23.6 14.0 9.1e-05 21.6 14.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF973) DUF962 PF06127.11 AAL64248.1 - 0.026 14.6 8.6 27 5.0 8.6 3.1 1 1 0 1 1 1 0 Protein of unknown function (DUF962) FeoB_associated PF12669.7 AAL64248.1 - 0.78 10.2 0.1 0.78 10.2 0.1 4.8 4 1 1 5 5 5 0 FeoB-associated Cys-rich membrane protein DUF1240 PF06836.12 AAL64248.1 - 1.2 9.7 5.3 16 6.1 0.1 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1240) Wzy_C_2 PF11846.8 AAL64248.1 - 1.8 8.4 10.3 0.76 9.7 2.3 2.2 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal Phage_holin_3_6 PF07332.11 AAL64248.1 - 3 7.9 43.4 0.23 11.5 2.7 3.1 1 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4231 PF14015.6 AAL64248.1 - 3.1 8.3 8.5 2 8.9 3.8 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF4231) Aminotran_3 PF00202.21 AAL64249.1 - 4.3e-100 335.2 0.0 6.3e-100 334.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_5 PF00266.19 AAL64249.1 - 0.00057 18.9 0.0 0.001 18.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 AAL64249.1 - 0.054 12.7 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II DUF3673 PF12425.8 AAL64249.1 - 0.15 12.0 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3673) CCB2_CCB4 PF11152.8 AAL64249.1 - 0.16 11.2 0.0 11 5.3 0.0 2.3 2 0 0 2 2 2 0 Cofactor assembly of complex C subunit B, CCB2/CCB4 MJ1316 PF04457.12 AAL64251.1 - 6.8e-07 29.9 0.0 7.7e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain Carb_kinase PF01256.17 AAL64252.1 - 1.9e-55 188.0 1.6 1.9e-55 188.0 1.6 1.5 2 0 0 2 2 2 1 Carbohydrate kinase YjeF_N PF03853.15 AAL64252.1 - 1.1e-42 145.9 0.4 3.2e-42 144.3 0.2 1.9 2 0 0 2 2 2 1 YjeF-related protein N-terminus HK PF02110.15 AAL64252.1 - 1.5e-08 34.4 0.2 2.3e-08 33.7 0.2 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.12 AAL64252.1 - 0.00021 20.8 0.1 0.00036 20.0 0.1 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PaREP1 PF05942.11 AAL64253.1 - 1.9e-24 85.8 10.5 2.4e-24 85.4 10.5 1.2 1 0 0 1 1 1 1 Archaeal PaREP1/PaREP8 family HEPN PF05168.14 AAL64253.1 - 0.019 15.1 2.7 0.033 14.3 2.7 1.5 1 1 0 1 1 1 0 HEPN domain OrfB_Zn_ribbon PF07282.11 AAL64255.1 - 3.7e-10 39.6 0.1 7.8e-10 38.5 0.1 1.5 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Vps16_C PF04840.12 AAL64255.1 - 0.0059 15.7 0.0 0.0085 15.2 0.0 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region DNA_RNApol_7kD PF03604.13 AAL64255.1 - 0.056 13.1 3.4 0.13 12.0 3.4 1.6 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Ribosomal_L37e PF01907.19 AAL64255.1 - 0.096 12.9 0.3 0.23 11.6 0.3 1.6 1 0 0 1 1 1 0 Ribosomal protein L37e FYVE_2 PF02318.16 AAL64255.1 - 0.15 12.2 0.0 0.15 12.2 0.0 2.2 3 0 0 3 3 3 0 FYVE-type zinc finger zf-TFIIB PF13453.6 AAL64255.1 - 0.17 11.3 3.6 0.58 9.5 3.4 2.0 2 0 0 2 2 2 0 Transcription factor zinc-finger FYVE PF01363.21 AAL64255.1 - 0.19 11.9 1.5 0.38 10.9 1.5 1.4 1 0 0 1 1 1 0 FYVE zinc finger zf_UBZ PF18439.1 AAL64255.1 - 0.95 9.1 2.4 24 4.6 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DUF981 PF06168.11 AAL64257.1 - 5.2e-54 183.0 20.8 6.1e-54 182.8 20.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF981) DUF2232 PF09991.9 AAL64257.1 - 0.0018 17.5 8.5 0.0018 17.5 8.5 2.4 1 1 1 2 2 2 2 Predicted membrane protein (DUF2232) DUF4064 PF13273.6 AAL64257.1 - 2.9 8.2 15.4 11 6.3 6.3 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) ThiW PF09512.10 AAL64258.1 - 1.2e-43 148.8 15.5 1.3e-43 148.6 15.5 1.0 1 0 0 1 1 1 1 Thiamine-precursor transporter protein (ThiW) NACHT PF05729.12 AAL64259.1 - 0.00044 20.2 0.1 0.0011 18.9 0.1 1.6 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 AAL64259.1 - 0.00081 19.2 0.3 0.0011 18.8 0.3 1.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAL64259.1 - 0.0023 18.4 0.3 0.0037 17.7 0.3 1.3 1 1 0 1 1 1 1 AAA ATPase domain ATP_bind_1 PF03029.17 AAL64259.1 - 0.0044 16.8 0.1 0.0073 16.1 0.1 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MobB PF03205.14 AAL64259.1 - 0.0047 16.8 0.1 0.0085 16.0 0.1 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_7 PF12775.7 AAL64259.1 - 0.015 14.8 0.1 0.41 10.1 0.1 2.3 2 1 1 3 3 3 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 AAL64259.1 - 0.017 14.5 0.1 0.025 14.0 0.1 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 AAL64259.1 - 0.033 14.5 0.3 0.045 14.0 0.3 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AAL64259.1 - 0.037 13.6 0.3 0.057 13.0 0.3 1.5 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AAL64259.1 - 0.049 14.2 0.3 0.088 13.3 0.3 1.4 1 0 0 1 1 1 0 ABC transporter DUF2075 PF09848.9 AAL64259.1 - 0.071 12.3 0.1 0.096 11.9 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 AAL64259.1 - 0.077 13.3 0.3 0.18 12.2 0.3 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AAL64259.1 - 0.085 12.6 0.0 0.095 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 AAL64259.1 - 0.094 12.2 0.2 0.13 11.7 0.2 1.1 1 0 0 1 1 1 0 Poxvirus A32 protein TrwB_AAD_bind PF10412.9 AAL64259.1 - 0.098 11.5 0.1 0.14 11.1 0.1 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain NTPase_1 PF03266.15 AAL64259.1 - 0.11 12.4 0.2 0.26 11.2 0.1 1.6 2 0 0 2 2 2 0 NTPase Adeno_IVa2 PF02456.15 AAL64259.1 - 0.13 11.0 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_10 PF12846.7 AAL64259.1 - 0.2 10.6 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain NB-ARC PF00931.22 AAL64259.1 - 0.23 10.6 0.2 0.37 9.9 0.2 1.2 1 0 0 1 1 1 0 NB-ARC domain DAP3 PF10236.9 AAL64259.1 - 0.27 10.4 0.2 0.36 9.9 0.2 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 ABC_tran PF00005.27 AAL64260.1 - 8.3e-24 84.7 0.6 1.9e-05 25.2 0.0 4.1 3 1 0 4 4 4 4 ABC transporter AAA_21 PF13304.6 AAL64260.1 - 3.4e-20 73.0 0.1 1.5e-06 28.2 0.0 4.1 2 2 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAL64260.1 - 1.7e-08 34.2 0.5 0.00032 20.2 0.0 3.8 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 AAL64260.1 - 7.5e-07 29.0 0.0 0.0051 16.6 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA PF00004.29 AAL64260.1 - 1.9e-05 25.1 0.0 0.15 12.5 0.0 2.4 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 AAL64260.1 - 6.6e-05 22.6 0.2 0.15 11.8 0.0 3.5 4 0 0 4 4 4 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AAL64260.1 - 0.00062 20.2 0.0 0.032 14.6 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 AAL64260.1 - 0.0009 18.9 1.6 1.2 8.7 0.1 3.1 2 1 0 3 3 3 2 AAA domain AAA_22 PF13401.6 AAL64260.1 - 0.0012 19.1 0.1 2.1 8.6 0.1 2.5 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 AAL64260.1 - 0.0016 19.0 0.0 1.3 9.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 AAL64260.1 - 0.0024 18.4 0.0 0.019 15.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 AAL64260.1 - 0.0029 17.4 0.1 4.4 7.0 0.0 2.9 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_28 PF13521.6 AAL64260.1 - 0.0031 17.8 0.8 1.7 8.9 0.1 2.6 2 1 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 AAL64260.1 - 0.0065 16.8 0.1 0.34 11.3 0.0 2.2 2 0 0 2 2 2 1 RNA helicase RsgA_GTPase PF03193.16 AAL64260.1 - 0.01 15.8 0.0 0.099 12.5 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase T2SSE PF00437.20 AAL64260.1 - 0.011 14.8 0.0 0.28 10.2 0.0 2.3 3 0 0 3 3 3 0 Type II/IV secretion system protein TsaE PF02367.17 AAL64260.1 - 0.026 14.5 0.0 4.7 7.2 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 AAL64260.1 - 0.032 13.4 0.0 0.22 10.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 AAL64260.1 - 0.036 13.8 0.3 1.4 8.6 0.2 2.2 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 AAL64260.1 - 0.053 13.0 0.2 4.4 6.8 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region SbcCD_C PF13558.6 AAL64260.1 - 0.055 13.7 0.0 2.6 8.4 0.0 2.7 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 AAL64260.1 - 0.087 12.8 0.1 6 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SRP54 PF00448.22 AAL64260.1 - 0.096 12.3 0.8 3.6 7.2 0.3 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 AAL64260.1 - 0.14 12.3 0.0 7.4 6.7 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 AAL64260.1 - 0.16 12.3 0.0 5 7.5 0.1 2.3 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 AAL64260.1 - 0.18 11.5 1.8 10 5.8 0.1 3.0 3 0 0 3 3 3 0 Cytidylate kinase AAA_15 PF13175.6 AAL64260.1 - 0.37 10.5 0.1 33 4.0 0.0 2.8 2 1 1 3 3 3 0 AAA ATPase domain Phos_pyr_kin PF08543.12 AAL64262.1 - 3.9e-93 311.4 0.4 5.5e-93 310.9 0.4 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase ThiP_synth PF10120.9 AAL64262.1 - 3.7e-58 195.8 1.3 1.7e-57 193.6 0.4 2.1 2 0 0 2 2 2 1 Thiamine-phosphate synthase PfkB PF00294.24 AAL64262.1 - 2e-12 47.1 0.2 3e-12 46.4 0.2 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase MRP_L53 PF10780.9 AAL64262.1 - 0.0028 17.8 0.0 0.012 15.8 0.0 2.0 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 5-FTHF_cyc-lig PF01812.20 AAL64263.1 - 7.7e-33 113.9 0.0 9.6e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family SDH_sah PF01972.16 AAL64264.1 - 3.8e-06 26.1 0.6 5.2e-06 25.7 0.6 1.2 1 0 0 1 1 1 1 Serine dehydrogenase proteinase CLP_protease PF00574.23 AAL64264.1 - 0.019 14.9 0.5 0.036 14.0 0.5 1.5 1 1 0 1 1 1 0 Clp protease Peptidase_S49 PF01343.18 AAL64264.1 - 0.026 14.5 1.1 0.045 13.7 0.6 1.6 2 0 0 2 2 2 0 Peptidase family S49 ATPase_2 PF01637.18 AAL64265.1 - 3.1e-15 56.7 0.0 5e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 AAL64265.1 - 1.5e-11 44.9 0.3 2.7e-11 44.1 0.3 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 AAL64265.1 - 4e-10 39.8 0.0 2.5e-07 30.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AAL64265.1 - 1.2e-05 25.6 0.0 2.7e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain GAF_3 PF13492.6 AAL64265.1 - 0.028 14.8 0.0 0.052 13.9 0.0 1.4 1 0 0 1 1 1 0 GAF domain AAA_24 PF13479.6 AAL64265.1 - 0.2 11.4 0.0 1.7 8.3 0.0 2.2 1 1 0 1 1 1 0 AAA domain Beta_propel PF09826.9 AAL64267.1 - 1.7e-87 294.4 0.0 5.5e-85 286.2 0.0 3.0 1 1 0 1 1 1 1 Beta propeller domain LVIVD PF08309.11 AAL64267.1 - 0.98 8.8 3.5 36 3.8 0.0 3.6 3 0 0 3 3 3 0 LVIVD repeat Polbeta PF18765.1 AAL64268.1 - 3.9e-22 78.1 0.0 5.6e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 AAL64268.1 - 3.4e-11 43.3 0.7 8.1e-11 42.1 0.6 1.7 1 1 1 2 2 2 1 Nucleotidyltransferase domain RlaP PF10127.9 AAL64268.1 - 0.054 13.1 0.0 0.074 12.6 0.0 1.2 1 0 0 1 1 1 0 RNA repair pathway DNA polymerase beta family DUF2070 PF09843.9 AAL64270.1 - 0.33 9.2 16.9 0.39 8.9 16.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF5392 PF17370.2 AAL64270.1 - 4.7 7.3 9.0 7.4 6.6 9.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5392) HEPN PF05168.14 AAL64272.1 - 1.1e-30 106.1 0.3 1.3e-30 105.9 0.3 1.0 1 0 0 1 1 1 1 HEPN domain POTRA_2 PF08479.11 AAL64272.1 - 0.092 12.6 0.1 0.13 12.2 0.1 1.2 1 0 0 1 1 1 0 POTRA domain, ShlB-type NTP_transf_2 PF01909.23 AAL64273.1 - 1e-08 35.3 0.0 1.2e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 AAL64273.1 - 5.2e-07 29.7 0.0 7.1e-07 29.2 0.0 1.4 1 1 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase DUF294 PF03445.13 AAL64273.1 - 0.0085 15.9 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Putative nucleotidyltransferase DUF294 TauE PF01925.19 AAL64274.1 - 7.6e-28 97.7 27.1 8.7e-28 97.6 27.1 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE DUF2569 PF10754.9 AAL64275.1 - 0.054 13.9 3.6 0.098 13.1 3.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2569) Gln-synt_C PF00120.24 AAL64276.1 - 1.7e-94 316.7 0.0 2.6e-94 316.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 AAL64276.1 - 4.2e-13 48.8 0.0 8e-13 47.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Gln-synt_N_2 PF16952.5 AAL64276.1 - 0.028 14.3 0.0 0.069 13.0 0.0 1.6 2 0 0 2 2 2 0 Glutamine synthetase N-terminal domain tRNA-synt_2 PF00152.20 AAL64277.1 - 8.4e-60 202.5 0.0 9.6e-60 202.3 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2704 PF10866.8 AAL64277.1 - 0.072 13.0 0.3 0.15 11.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2704) MFS_1 PF07690.16 AAL64278.1 - 2.8e-40 138.3 61.0 1.6e-31 109.5 26.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AAL64278.1 - 4.2e-09 35.8 11.2 4.2e-09 35.8 11.2 2.6 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 AAL64278.1 - 2.2e-06 27.2 14.5 2.2e-06 27.2 14.5 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 AAL64278.1 - 8.3e-05 21.3 2.5 8.3e-05 21.3 2.5 3.3 1 1 1 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.13 AAL64278.1 - 0.0004 19.0 7.1 0.00069 18.2 7.1 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 AAL64278.1 - 0.00084 18.3 11.9 0.0033 16.3 0.1 3.4 2 1 0 3 3 3 2 MFS_1 like family DUF4271 PF14093.6 AAL64278.1 - 0.18 11.7 3.3 0.62 9.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) Fer4 PF00037.27 AAL64280.1 - 1.1e-09 37.7 13.4 2.9e-06 26.9 2.3 2.1 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 AAL64280.1 - 2.6e-09 37.5 12.9 5e-09 36.6 13.1 1.4 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAL64280.1 - 2.7e-09 37.1 11.9 3.2e-09 36.8 11.9 1.1 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 AAL64280.1 - 1.6e-08 34.3 16.2 2.6e-05 24.1 3.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 AAL64280.1 - 2.1e-08 34.1 26.5 3.1e-06 27.2 15.2 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAL64280.1 - 4e-08 34.1 9.3 0.00024 22.0 1.1 2.1 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_2 PF12797.7 AAL64280.1 - 3.1e-07 30.1 12.6 0.0003 20.7 2.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 AAL64280.1 - 4.6e-06 26.7 16.7 0.00046 20.5 4.2 2.2 1 1 1 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 AAL64280.1 - 6.4e-06 26.2 8.3 0.0034 17.5 1.6 2.0 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 AAL64280.1 - 0.00046 20.9 17.3 0.025 15.5 3.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 AAL64280.1 - 0.0005 20.6 15.5 0.094 13.3 2.9 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 AAL64280.1 - 0.0011 19.3 14.7 0.036 14.5 14.7 2.1 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_22 PF17179.4 AAL64280.1 - 0.003 18.4 6.7 0.045 14.6 0.9 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_18 PF13746.6 AAL64280.1 - 0.0033 17.6 9.5 0.026 14.7 0.8 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 AAL64280.1 - 0.014 15.9 13.3 0.5 11.0 2.4 2.1 1 1 1 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 AAL64280.1 - 0.2 12.4 8.4 0.46 11.3 0.9 2.1 2 0 0 2 2 2 0 4Fe-4S single cluster domain APS-reductase_C PF12139.8 AAL64281.1 - 3e-15 56.2 0.0 3.4e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 Adenosine-5'-phosphosulfate reductase beta subunit FAD_binding_2 PF00890.24 AAL64282.1 - 7.6e-12 45.0 1.7 3.2e-10 39.7 0.0 2.9 2 1 1 3 3 3 1 FAD binding domain DAO PF01266.24 AAL64282.1 - 1.8e-06 27.8 0.1 6.1e-05 22.8 0.1 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 AAL64282.1 - 0.0016 17.6 4.5 0.57 9.2 1.2 2.5 3 0 0 3 3 3 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 AAL64282.1 - 0.018 14.3 2.0 0.021 14.1 0.4 1.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AAL64282.1 - 0.097 12.0 0.1 0.24 10.7 0.1 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 AAL64282.1 - 0.11 11.2 0.2 0.64 8.7 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Succ_DH_flav_C PF02910.20 AAL64283.1 - 7.6e-09 35.6 0.0 1.2e-08 35.0 0.0 1.4 1 1 0 1 1 1 1 Fumarate reductase flavoprotein C-term Metallophos_2 PF12850.7 AAL64284.1 - 2.4e-32 112.4 0.1 2.7e-32 112.2 0.1 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 AAL64284.1 - 8.2e-08 33.0 0.8 1.2e-05 25.9 0.0 2.1 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_3 PF14582.6 AAL64284.1 - 0.0017 17.8 0.2 0.0076 15.6 0.2 1.9 1 1 1 2 2 2 1 Metallophosphoesterase, calcineurin superfamily DsrC PF04358.13 AAL64285.1 - 5.5e-35 120.1 0.0 6.2e-35 119.9 0.0 1.0 1 0 0 1 1 1 1 DsrC like protein MerR-DNA-bind PF09278.11 AAL64285.1 - 0.048 14.2 0.0 0.78 10.3 0.0 2.1 2 0 0 2 2 2 0 MerR, DNA binding DrsE PF02635.15 AAL64286.1 - 3.4e-21 75.8 0.0 3.7e-21 75.6 0.0 1.0 1 0 0 1 1 1 1 DsrE/DsrF-like family DrsE_2 PF13686.6 AAL64286.1 - 7.7e-11 42.1 2.9 1.5e-07 31.5 0.4 2.1 1 1 1 2 2 2 2 DsrE/DsrF/DrsH-like family NIR_SIR PF01077.22 AAL64288.1 - 2e-41 141.2 0.0 2.9e-41 140.6 0.0 1.2 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 AAL64288.1 - 1.4e-08 34.5 0.0 2.7e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Fer4_8 PF13183.6 AAL64288.1 - 0.003 18.0 0.1 0.049 14.1 0.0 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAL64288.1 - 0.0053 16.9 1.9 0.0053 16.9 1.9 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AAL64288.1 - 0.03 14.9 3.5 0.15 12.6 3.7 2.0 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 AAL64288.1 - 0.036 14.2 1.0 0.11 12.7 1.0 1.8 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 AAL64288.1 - 0.04 14.5 0.8 0.13 12.8 0.8 1.8 1 0 0 1 1 1 0 4Fe-4S single cluster domain of Ferredoxin I Fer4 PF00037.27 AAL64288.1 - 0.87 9.5 9.5 4.3 7.3 4.5 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.7 AAL64288.1 - 3.2 8.0 7.7 4.6 7.5 3.8 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain NIR_SIR PF01077.22 AAL64289.1 - 3.6e-23 81.8 0.2 5.2e-23 81.3 0.2 1.2 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 AAL64289.1 - 0.038 13.8 0.1 0.17 11.7 0.0 2.1 3 0 0 3 3 3 0 Nitrite/Sulfite reductase ferredoxin-like half domain ImmE5 PF11480.8 AAL64289.1 - 0.11 13.0 0.1 0.21 12.1 0.1 1.4 1 0 0 1 1 1 0 Colicin-E5 Imm protein TP_methylase PF00590.20 AAL64290.1 - 3.3e-43 148.1 0.4 3.9e-43 147.9 0.4 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases TSC22 PF01166.18 AAL64291.1 - 0.0093 16.3 0.0 5.3 7.4 0.0 2.2 2 0 0 2 2 2 2 TSC-22/dip/bun family PAPS_reduct PF01507.19 AAL64292.1 - 1.1e-45 155.9 0.0 1.4e-45 155.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family NIR_SIR PF01077.22 AAL64294.1 - 2.4e-50 170.2 0.0 3.8e-42 143.5 0.0 2.3 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 AAL64294.1 - 1.3e-36 124.2 0.1 5.5e-17 61.4 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Ribosomal_L12_N PF16320.5 AAL64294.1 - 0.32 10.7 1.0 17 5.2 0.2 3.5 4 0 0 4 4 4 0 Ribosomal protein L7/L12 dimerisation domain TauE PF01925.19 AAL64295.1 - 7.2e-19 68.3 24.1 7.2e-19 68.3 24.1 1.3 2 0 0 2 2 2 1 Sulfite exporter TauE/SafE ThiS PF02597.20 AAL64296.1 - 3e-15 56.6 0.1 3.3e-15 56.5 0.1 1.0 1 0 0 1 1 1 1 ThiS family S4 PF01479.25 AAL64296.1 - 0.027 14.2 0.2 0.048 13.4 0.2 1.4 1 0 0 1 1 1 0 S4 domain S4_2 PF13275.6 AAL64296.1 - 0.027 14.3 0.8 0.26 11.1 0.0 2.2 2 1 1 3 3 3 0 S4 domain Ub-Mut7C PF14451.6 AAL64296.1 - 0.084 12.7 0.1 0.18 11.7 0.1 1.6 1 1 0 1 1 1 0 Mut7-C ubiquitin Rhodanese PF00581.20 AAL64297.1 - 2e-27 95.8 0.3 2.6e-13 50.4 0.2 2.2 2 0 0 2 2 2 2 Rhodanese-like domain PaREP1 PF05942.11 AAL64298.1 - 9e-15 54.6 0.7 9.1e-15 54.6 0.7 1.0 1 0 0 1 1 1 1 Archaeal PaREP1/PaREP8 family GATase_3 PF07685.14 AAL64299.1 - 7.1e-25 87.8 0.0 1.1e-24 87.1 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AAA_26 PF13500.6 AAL64299.1 - 1e-10 41.8 1.9 3.8e-10 39.9 1.2 2.1 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 AAL64299.1 - 1.8e-05 24.8 0.0 3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain IncF PF17626.2 AAL64299.1 - 0.013 15.8 0.3 0.034 14.5 0.3 1.7 1 0 0 1 1 1 0 Inclusion membrane protein F AAA_26 PF13500.6 AAL64300.1 - 0.066 13.0 0.1 0.066 13.0 0.1 1.0 1 0 0 1 1 1 0 AAA domain RHH_5 PF07878.11 AAL64301.1 - 0.082 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 COXG PF06240.13 AAL64302.1 - 0.13 12.0 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Carbon monoxide dehydrogenase subunit G (CoxG) HEM4 PF02602.15 AAL64303.1 - 1e-10 41.3 3.6 1e-10 41.3 3.6 1.3 1 1 0 1 1 1 1 Uroporphyrinogen-III synthase HemD E3_binding PF02817.17 AAL64303.1 - 0.04 14.3 4.0 5.7 7.4 0.7 3.2 3 0 0 3 3 3 0 e3 binding domain HEM4 PF02602.15 AAL64304.1 - 1.4e-27 96.5 1.4 1.7e-27 96.3 1.4 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD BetR PF08667.10 AAL64304.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 BetR domain ANF_receptor PF01094.28 AAL64304.1 - 0.16 11.0 0.0 0.4 9.7 0.0 1.5 1 1 0 1 1 1 0 Receptor family ligand binding region NIR_SIR PF01077.22 AAL64305.1 - 1.5e-19 70.1 0.1 2.2e-19 69.5 0.1 1.2 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 AAL64305.1 - 2.2e-06 27.4 0.0 9.7e-06 25.3 0.0 2.1 3 0 0 3 3 3 1 Nitrite/Sulfite reductase ferredoxin-like half domain ImmE5 PF11480.8 AAL64305.1 - 0.1 13.1 0.1 0.21 12.1 0.1 1.5 1 0 0 1 1 1 0 Colicin-E5 Imm protein NIR_SIR PF01077.22 AAL64306.1 - 1.6e-38 131.7 0.0 2.4e-38 131.1 0.0 1.2 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 AAL64306.1 - 1.4e-08 34.4 0.0 2.5e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Fer4 PF00037.27 AAL64306.1 - 1.6e-05 24.5 8.7 0.0042 16.9 4.3 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 AAL64306.1 - 0.0021 18.6 3.3 0.0027 18.3 1.6 2.0 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_13 PF13370.6 AAL64306.1 - 0.003 18.1 2.0 0.37 11.4 0.5 2.7 2 0 0 2 2 2 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_9 PF13187.6 AAL64306.1 - 0.0034 17.5 1.1 0.01 16.0 1.1 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_15 PF13459.6 AAL64306.1 - 0.0075 17.0 1.5 0.95 10.2 0.2 2.5 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_8 PF13183.6 AAL64306.1 - 0.013 16.0 0.4 0.1 13.0 0.2 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAL64306.1 - 0.018 16.0 2.3 2 9.4 1.2 2.5 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain Fer4_6 PF12837.7 AAL64306.1 - 0.23 11.6 10.0 1.1 9.5 5.1 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_10 PF13237.6 AAL64306.1 - 2 8.6 10.3 0.073 13.2 2.2 2.3 3 1 1 4 4 4 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 AAL64306.1 - 3.2 8.0 8.6 0.82 9.8 4.5 2.1 2 1 0 2 2 2 0 4Fe-4S dicluster domain TrmB PF01978.19 AAL64308.1 - 0.00072 19.4 0.1 0.0015 18.3 0.1 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB TusA PF01206.17 AAL64310.1 - 4.6e-24 84.0 0.1 5e-24 83.9 0.1 1.0 1 0 0 1 1 1 1 Sulfurtransferase TusA TusA PF01206.17 AAL64311.1 - 3e-20 71.8 0.0 3.4e-20 71.6 0.0 1.0 1 0 0 1 1 1 1 Sulfurtransferase TusA DUF2249 PF10006.9 AAL64311.1 - 0.0012 18.7 0.0 0.0028 17.5 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2249) Acylphosphatase PF00708.18 AAL64312.1 - 3e-22 78.8 0.1 6.6e-22 77.7 0.1 1.6 1 0 0 1 1 1 1 Acylphosphatase AIRS_C PF02769.22 AAL64312.1 - 0.0081 16.3 1.0 0.025 14.7 0.1 2.2 2 1 0 2 2 2 1 AIR synthase related protein, C-terminal domain DrsE PF02635.15 AAL64313.1 - 1.5e-06 28.5 0.0 1.9e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 DsrE/DsrF-like family DrsE_2 PF13686.6 AAL64313.1 - 0.13 12.2 0.2 2.7 7.9 0.0 2.0 1 1 1 2 2 2 0 DsrE/DsrF/DrsH-like family HEPN PF05168.14 AAL64314.1 - 0.00034 20.7 0.0 0.00057 20.0 0.0 1.4 1 1 0 1 1 1 1 HEPN domain ATP-sulfurylase PF01747.17 AAL64316.1 - 2e-71 239.8 0.0 2.9e-71 239.3 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 AAL64316.1 - 5.8e-43 146.3 0.0 1.7e-42 144.8 0.0 1.7 2 0 0 2 2 2 1 PUA-like domain DUF309 PF03745.14 AAL64316.1 - 0.12 12.1 0.7 0.23 11.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF309) Nitrate_red_gam PF02665.14 AAL64318.1 - 1.7e-39 135.6 12.0 2.2e-37 128.8 6.7 2.1 2 0 0 2 2 2 2 Nitrate reductase gamma subunit CCG PF02754.16 AAL64320.1 - 2.2e-05 24.6 0.0 0.00012 22.2 0.1 2.2 2 0 0 2 2 2 1 Cysteine-rich domain Fer4_17 PF13534.6 AAL64320.1 - 0.00019 21.9 0.1 0.00037 21.0 0.1 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 AAL64320.1 - 0.0017 18.8 0.1 0.0035 17.7 0.1 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AAL64320.1 - 0.0018 18.8 0.1 0.0041 17.7 0.1 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAL64320.1 - 0.0029 17.7 0.0 0.0057 16.7 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAL64320.1 - 0.0053 16.9 0.2 0.011 15.8 0.2 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_4 PF12800.7 AAL64320.1 - 0.0064 16.9 1.6 0.016 15.7 1.6 1.6 1 0 0 1 1 1 1 4Fe-4S binding domain Fer4_2 PF12797.7 AAL64320.1 - 0.007 16.4 1.1 0.013 15.5 1.1 1.5 1 0 0 1 1 1 1 4Fe-4S binding domain Fer4 PF00037.27 AAL64320.1 - 0.013 15.2 1.4 0.027 14.3 1.4 1.5 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4_16 PF13484.6 AAL64320.1 - 0.035 15.1 0.2 0.092 13.7 0.2 1.7 1 0 0 1 1 1 0 4Fe-4S double cluster binding domain Fer4_6 PF12837.7 AAL64320.1 - 0.05 13.7 2.8 0.1 12.7 2.8 1.5 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4_3 PF12798.7 AAL64320.1 - 0.23 12.5 2.9 0.5 11.4 2.9 1.6 1 0 0 1 1 1 0 4Fe-4S binding domain Pyr_redox_2 PF07992.14 AAL64321.1 - 4.3e-16 59.0 0.0 1.3e-15 57.4 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 AAL64321.1 - 0.00021 21.3 0.1 0.021 14.8 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 AAL64321.1 - 0.00039 20.1 0.7 0.0012 18.6 0.2 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AAL64321.1 - 0.0088 16.2 0.2 0.037 14.3 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 AAL64321.1 - 0.036 14.6 0.2 0.48 11.0 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AAL64321.1 - 0.042 12.6 0.2 1.3 7.6 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 AAL64321.1 - 0.043 12.9 0.3 0.8 8.7 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 AAL64321.1 - 0.071 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 AAL64321.1 - 0.093 11.6 0.0 0.2 10.5 0.0 1.5 2 0 0 2 2 2 0 Tryptophan halogenase DUF1641 PF07849.11 AAL64322.1 - 2.9e-18 65.4 1.1 5.5e-18 64.5 1.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1641) DUF3562 PF12085.8 AAL64322.1 - 0.003 17.1 0.0 2.1 8.0 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3562) Pyr_redox_2 PF07992.14 AAL64324.1 - 9.1e-59 199.1 5.3 1.3e-58 198.6 5.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 AAL64324.1 - 7e-21 74.6 0.0 2.9e-20 72.6 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_3 PF13738.6 AAL64324.1 - 4.6e-17 62.2 2.1 3e-16 59.5 2.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AAL64324.1 - 1.2e-14 54.2 15.4 1.8e-11 43.8 0.6 3.3 2 1 1 4 4 4 2 Glucose inhibited division protein A Pyr_redox PF00070.27 AAL64324.1 - 2.2e-13 50.5 8.8 1.8e-10 41.2 0.8 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AAL64324.1 - 3.9e-11 43.0 2.0 4e-10 39.6 0.9 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 AAL64324.1 - 6.2e-07 28.9 1.2 5.1e-06 25.9 0.0 2.2 2 1 1 3 3 2 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 AAL64324.1 - 1.7e-06 27.4 18.8 0.00032 19.9 8.4 3.1 2 1 0 3 3 3 2 FAD binding domain HI0933_like PF03486.14 AAL64324.1 - 0.00011 21.0 6.5 0.0011 17.7 3.1 3.1 3 0 0 3 3 3 1 HI0933-like protein AlaDh_PNT_C PF01262.21 AAL64324.1 - 0.00039 19.8 8.1 0.0021 17.4 2.9 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 AAL64324.1 - 0.00099 18.8 13.7 0.014 15.0 12.0 3.5 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 AAL64324.1 - 0.0054 17.2 2.1 3.2 8.2 0.1 2.6 2 0 0 2 2 2 2 Putative NAD(P)-binding NAD_binding_9 PF13454.6 AAL64324.1 - 0.014 15.4 2.9 0.018 15.0 0.1 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding XdhC_C PF13478.6 AAL64324.1 - 0.015 15.8 0.4 1.9 9.0 0.0 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain Thi4 PF01946.17 AAL64324.1 - 0.015 14.6 3.8 0.067 12.4 1.5 2.8 2 0 0 2 2 2 0 Thi4 family 2-Hacid_dh_C PF02826.19 AAL64324.1 - 0.03 13.7 1.9 2.5 7.4 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glyco_transf_4 PF13439.6 AAL64324.1 - 0.058 13.4 0.1 0.15 12.0 0.1 1.7 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AAL64324.1 - 0.085 13.3 0.9 0.2 12.1 0.2 1.9 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain DUF4388 PF14332.6 AAL64324.1 - 0.12 12.7 0.0 0.35 11.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4388) F420_oxidored PF03807.17 AAL64324.1 - 0.26 11.9 6.3 0.48 11.1 0.2 3.0 3 0 0 3 3 2 0 NADP oxidoreductase coenzyme F420-dependent Trp_halogenase PF04820.14 AAL64324.1 - 0.48 9.2 2.5 0.29 9.9 0.3 1.8 2 0 0 2 2 2 0 Tryptophan halogenase FAD_binding_3 PF01494.19 AAL64324.1 - 0.48 9.6 4.3 7.9 5.6 2.1 2.2 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 AAL64324.1 - 1 8.3 15.7 0.79 8.7 3.4 3.5 3 1 1 4 4 4 0 Lycopene cyclase protein 3HCDH_N PF02737.18 AAL64324.1 - 1.7 8.5 7.3 2.5 8.0 0.1 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 AAL64324.1 - 3.1 8.1 9.4 2 8.7 2.9 2.7 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AAL64326.1 - 2.9e-20 72.7 0.5 4.6e-10 39.2 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase TAT_signal PF10518.9 AAL64326.1 - 0.00063 19.5 0.7 0.0015 18.3 0.7 1.7 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence UCR_Fe-S_N PF10399.9 AAL64326.1 - 0.0047 16.2 0.3 0.015 14.7 0.3 1.9 1 0 0 1 1 1 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Lycopene_cycl PF05834.12 AAL64326.1 - 0.02 14.0 0.3 0.034 13.2 0.3 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.24 AAL64326.1 - 0.022 14.4 4.4 0.09 12.3 3.6 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 AAL64326.1 - 0.069 13.7 1.6 5.1 7.7 1.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 AAL64326.1 - 0.14 11.4 3.5 0.23 10.7 3.5 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 AAL64326.1 - 0.16 11.1 2.5 0.18 10.8 1.6 1.5 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.6 AAL64326.1 - 0.26 11.6 1.3 0.48 10.7 0.3 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 AAL64326.1 - 0.32 10.2 0.7 0.48 9.6 0.7 1.2 1 0 0 1 1 1 0 FAD binding domain Cytochrom_D1 PF02239.16 AAL64328.1 - 1.7e-05 23.6 0.0 0.0022 16.6 0.0 2.5 2 1 0 2 2 2 1 Cytochrome D1 heme domain DUF4446 PF14584.6 AAL64328.1 - 0.00026 21.0 1.6 0.0012 18.9 1.9 1.9 2 0 0 2 2 1 1 Protein of unknown function (DUF4446) Spc7 PF08317.11 AAL64328.1 - 0.00045 19.2 3.8 0.00065 18.7 3.8 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein AAA_13 PF13166.6 AAL64328.1 - 0.00089 18.0 0.6 0.0012 17.6 0.6 1.1 1 0 0 1 1 1 1 AAA domain HAP1_N PF04849.13 AAL64328.1 - 0.00098 18.4 4.6 0.0014 17.9 4.6 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region CENP-F_leu_zip PF10473.9 AAL64328.1 - 0.0011 19.0 2.6 0.0017 18.4 2.6 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Lebercilin PF15619.6 AAL64328.1 - 0.0012 18.6 4.7 0.0017 18.0 4.7 1.1 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease APG6_N PF17675.1 AAL64328.1 - 0.0012 19.3 6.1 0.0024 18.4 6.1 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region SYCE1 PF15233.6 AAL64328.1 - 0.0013 18.8 3.7 0.002 18.2 3.7 1.2 1 0 0 1 1 1 1 Synaptonemal complex central element protein 1 LRRFIP PF09738.9 AAL64328.1 - 0.0013 18.3 0.3 0.0018 17.8 0.3 1.1 1 0 0 1 1 1 1 LRRFIP family Atg14 PF10186.9 AAL64328.1 - 0.0016 17.6 4.3 0.0023 17.1 4.3 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 ATG16 PF08614.11 AAL64328.1 - 0.0019 18.4 6.5 0.0028 17.9 6.5 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.12 AAL64328.1 - 0.002 18.2 8.7 0.003 17.6 8.7 1.2 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein MAD PF05557.13 AAL64328.1 - 0.0025 16.3 2.5 0.0034 15.8 2.5 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein AI-2E_transport PF01594.16 AAL64328.1 - 0.0034 16.6 1.1 0.0048 16.1 1.1 1.2 1 0 0 1 1 1 1 AI-2E family transporter DHR10 PF18595.1 AAL64328.1 - 0.0037 17.3 6.2 0.0052 16.8 6.2 1.2 1 0 0 1 1 1 1 Designed helical repeat protein 10 domain OmpH PF03938.14 AAL64328.1 - 0.0039 17.5 4.6 0.0085 16.4 4.6 1.6 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) Phage_GP20 PF06810.11 AAL64328.1 - 0.0041 16.9 2.4 0.0069 16.2 2.4 1.3 1 0 0 1 1 1 1 Phage minor structural protein GP20 HOOK PF05622.12 AAL64328.1 - 0.0044 15.2 4.3 0.006 14.8 4.3 1.0 1 0 0 1 1 1 1 HOOK protein DUF812 PF05667.11 AAL64328.1 - 0.0052 15.7 3.6 0.0072 15.3 3.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) COG2 PF06148.11 AAL64328.1 - 0.006 16.7 0.4 0.01 15.9 0.4 1.3 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Nsp1_C PF05064.13 AAL64328.1 - 0.0066 16.2 4.5 0.012 15.4 4.5 1.3 1 0 0 1 1 1 1 Nsp1-like C-terminal region FlaC_arch PF05377.11 AAL64328.1 - 0.0072 16.7 2.2 0.019 15.4 2.2 1.8 1 0 0 1 1 1 1 Flagella accessory protein C (FlaC) HemX PF04375.14 AAL64328.1 - 0.0074 15.6 6.2 0.011 15.1 6.2 1.2 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase IFT57 PF10498.9 AAL64328.1 - 0.0096 14.9 4.9 0.017 14.1 4.9 1.3 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 TPD52 PF04201.15 AAL64328.1 - 0.011 15.3 2.2 0.018 14.7 2.2 1.2 1 0 0 1 1 1 0 Tumour protein D52 family DUF948 PF06103.11 AAL64328.1 - 0.012 15.9 5.4 0.16 12.3 6.2 2.3 2 1 0 2 2 1 0 Bacterial protein of unknown function (DUF948) BRE1 PF08647.11 AAL64328.1 - 0.012 15.7 4.2 0.02 15.0 4.2 1.2 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Filament PF00038.21 AAL64328.1 - 0.013 15.1 3.7 0.02 14.5 3.7 1.1 1 0 0 1 1 1 0 Intermediate filament protein GAS PF13851.6 AAL64328.1 - 0.015 14.6 5.5 0.024 14.0 5.5 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding EzrA PF06160.12 AAL64328.1 - 0.017 13.4 1.9 0.025 12.8 1.9 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF4618 PF15397.6 AAL64328.1 - 0.017 14.5 1.7 0.028 13.9 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) CCDC144C PF14915.6 AAL64328.1 - 0.021 14.0 3.2 0.03 13.5 3.2 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region FtsL PF04999.13 AAL64328.1 - 0.023 14.7 2.1 0.05 13.6 2.1 1.5 1 0 0 1 1 1 0 Cell division protein FtsL Fez1 PF06818.15 AAL64328.1 - 0.024 15.1 4.4 0.036 14.5 4.4 1.1 1 0 0 1 1 1 0 Fez1 DUF4330 PF14221.6 AAL64328.1 - 0.024 14.9 5.5 0.8 9.9 1.2 2.7 3 0 0 3 3 2 0 Domain of unknown function (DUF4330) DUF1664 PF07889.12 AAL64328.1 - 0.024 14.7 0.4 0.049 13.7 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF724 PF05266.14 AAL64328.1 - 0.026 14.3 1.6 0.041 13.7 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) TMPIT PF07851.13 AAL64328.1 - 0.029 13.6 1.8 0.044 13.0 1.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein TMF_TATA_bd PF12325.8 AAL64328.1 - 0.029 14.6 3.6 0.05 13.8 3.6 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.15 AAL64328.1 - 0.032 14.0 15.9 0.035 13.9 2.1 3.4 2 1 1 3 3 3 0 Septum formation initiator Cluap1 PF10234.9 AAL64328.1 - 0.033 13.6 3.3 0.052 12.9 3.3 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 ADIP PF11559.8 AAL64328.1 - 0.039 14.0 7.3 0.062 13.4 7.3 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding MT PF12777.7 AAL64328.1 - 0.042 12.9 0.4 0.074 12.1 0.4 1.3 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor PspA_IM30 PF04012.12 AAL64328.1 - 0.042 13.4 8.5 0.062 12.9 8.5 1.1 1 0 0 1 1 1 0 PspA/IM30 family Dor1 PF04124.12 AAL64328.1 - 0.045 12.4 1.4 0.073 11.7 1.4 1.2 1 0 0 1 1 1 0 Dor1-like family CC2-LZ PF16516.5 AAL64328.1 - 0.045 14.1 2.8 0.086 13.2 2.8 1.4 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator CENP-H PF05837.12 AAL64328.1 - 0.047 14.1 4.3 0.077 13.4 4.3 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) LMBR1 PF04791.16 AAL64328.1 - 0.05 12.5 0.1 0.073 12.0 0.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF148 PF02520.17 AAL64328.1 - 0.058 13.5 4.7 0.1 12.7 4.7 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF148 DUF713 PF05218.14 AAL64328.1 - 0.058 13.1 0.3 0.1 12.3 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF713) Sec3_C PF09763.9 AAL64328.1 - 0.059 11.8 1.0 0.08 11.3 1.0 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 BST2 PF16716.5 AAL64328.1 - 0.059 14.0 5.4 0.095 13.3 5.4 1.3 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 JAKMIP_CC3 PF16034.5 AAL64328.1 - 0.065 13.2 4.2 0.13 12.2 4.2 1.4 1 0 0 1 1 1 0 JAKMIP CC3 domain BLOC1_2 PF10046.9 AAL64328.1 - 0.065 13.5 7.1 0.11 12.8 7.1 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF5128 PF17170.4 AAL64328.1 - 0.071 12.3 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 6-bladed beta-propeller Tektin PF03148.14 AAL64328.1 - 0.071 11.9 2.9 0.1 11.4 2.9 1.1 1 0 0 1 1 1 0 Tektin family DUF3450 PF11932.8 AAL64328.1 - 0.072 12.4 7.7 0.11 11.7 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) FemAB PF02388.16 AAL64328.1 - 0.078 11.8 0.6 0.13 11.1 0.6 1.2 1 0 0 1 1 1 0 FemAB family FPP PF05911.11 AAL64328.1 - 0.081 11.1 2.1 0.11 10.7 2.1 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Lactonase PF10282.9 AAL64328.1 - 0.09 12.0 1.0 1 8.5 0.0 2.5 3 0 0 3 3 2 0 Lactonase, 7-bladed beta-propeller Laminin_II PF06009.12 AAL64328.1 - 0.1 12.6 3.7 0.17 11.9 3.7 1.2 1 0 0 1 1 1 0 Laminin Domain II DUF3573 PF12097.8 AAL64328.1 - 0.1 11.4 0.5 0.16 10.8 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF4407 PF14362.6 AAL64328.1 - 0.11 11.8 2.3 0.18 11.1 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PD40 PF07676.12 AAL64328.1 - 0.12 12.4 0.4 47 4.1 0.0 3.5 4 0 0 4 4 3 0 WD40-like Beta Propeller Repeat DUF2203 PF09969.9 AAL64328.1 - 0.13 13.0 0.9 0.23 12.2 0.9 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) UPF0242 PF06785.11 AAL64328.1 - 0.13 12.4 4.3 0.21 11.7 4.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus EMC3_TMCO1 PF01956.16 AAL64328.1 - 0.15 11.8 0.2 0.25 11.0 0.2 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF2730 PF10805.8 AAL64328.1 - 0.15 12.1 2.5 0.3 11.2 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) YabA PF06156.13 AAL64328.1 - 0.16 12.6 1.0 0.29 11.8 1.0 1.3 1 0 0 1 1 1 0 Initiation control protein YabA JIP_LZII PF16471.5 AAL64328.1 - 0.16 12.1 1.7 0.31 11.2 1.7 1.5 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II PspB PF06667.12 AAL64328.1 - 0.17 12.0 0.8 0.26 11.3 0.8 1.3 1 0 0 1 1 1 0 Phage shock protein B FH2 PF02181.23 AAL64328.1 - 0.17 11.0 1.4 0.25 10.4 1.4 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain Baculo_PEP_C PF04513.12 AAL64328.1 - 0.18 11.8 3.5 0.29 11.2 3.5 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Med9 PF07544.13 AAL64328.1 - 0.18 11.9 2.7 0.46 10.6 2.7 1.6 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Spc24 PF08286.11 AAL64328.1 - 0.2 11.9 4.1 0.097 12.9 1.5 1.7 2 0 0 2 2 1 0 Spc24 subunit of Ndc80 Seryl_tRNA_N PF02403.22 AAL64328.1 - 0.21 11.9 5.5 0.34 11.2 5.5 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF16 PF01519.16 AAL64328.1 - 0.21 12.1 1.6 0.42 11.1 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 KLRAQ PF10205.9 AAL64328.1 - 0.21 11.8 7.9 0.12 12.6 5.7 1.6 2 0 0 2 2 1 0 Predicted coiled-coil domain-containing protein Fib_alpha PF08702.10 AAL64328.1 - 0.23 11.6 2.4 0.38 10.9 2.4 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4795 PF16043.5 AAL64328.1 - 0.26 10.9 5.2 0.4 10.3 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Uso1_p115_C PF04871.13 AAL64328.1 - 0.28 11.6 7.7 0.42 11.0 7.7 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region tRNA_anti-like PF12869.7 AAL64328.1 - 0.28 10.8 2.0 0.5 10.0 2.0 1.4 1 0 0 1 1 1 0 tRNA_anti-like Yuri_gagarin PF15934.5 AAL64328.1 - 0.31 10.8 2.5 1.5 8.6 2.6 1.7 1 1 0 1 1 1 0 Yuri gagarin FlaG PF03646.15 AAL64328.1 - 0.35 11.1 2.6 1.9 8.7 2.6 2.1 1 1 0 1 1 1 0 FlaG protein PKcGMP_CC PF16808.5 AAL64328.1 - 0.35 10.8 1.2 0.69 9.8 1.1 1.6 1 1 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Phage_GPO PF05929.11 AAL64328.1 - 0.41 10.2 3.6 0.63 9.6 3.6 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase TSC22 PF01166.18 AAL64328.1 - 0.42 11.0 3.0 1.8 8.9 1.6 2.4 2 1 1 3 3 2 0 TSC-22/dip/bun family DUF1043 PF06295.12 AAL64328.1 - 0.53 10.3 4.0 0.98 9.4 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) GrpE PF01025.19 AAL64328.1 - 0.54 9.9 4.3 0.98 9.1 4.3 1.3 1 0 0 1 1 1 0 GrpE DUF5082 PF16888.5 AAL64328.1 - 0.56 10.5 5.5 1.1 9.5 5.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) SlyX PF04102.12 AAL64328.1 - 0.66 10.6 10.1 0.85 10.3 6.1 2.2 1 1 1 2 2 2 0 SlyX Sec2p PF06428.11 AAL64328.1 - 0.67 10.0 6.4 1.2 9.2 6.4 1.3 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p DUF4140 PF13600.6 AAL64328.1 - 0.84 10.1 4.1 2.1 8.8 4.1 1.6 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) SseC PF04888.12 AAL64328.1 - 0.88 9.1 4.9 1.4 8.5 4.9 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family ABC_tran_CTD PF16326.5 AAL64328.1 - 1.1 9.6 10.8 1.8 8.8 7.1 2.2 1 1 1 2 2 2 0 ABC transporter C-terminal domain HAUS-augmin3 PF14932.6 AAL64328.1 - 1.1 8.8 6.7 1.7 8.2 6.7 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Cnn_1N PF07989.11 AAL64328.1 - 1.4 9.1 6.7 2.4 8.4 6.7 1.3 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 DASH_Hsk3 PF08227.11 AAL64328.1 - 3.4 8.1 10.7 17 5.9 4.4 2.4 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like DUF4404 PF14357.6 AAL64328.1 - 4 8.1 7.7 6.8 7.4 7.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) DUF2304 PF10066.9 AAL64328.1 - 5.2 7.3 8.1 19 5.6 0.9 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) DUF2681 PF10883.8 AAL64328.1 - 5.4 7.5 8.9 16 5.9 8.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) LPP PF04728.13 AAL64328.1 - 5.5 7.5 8.3 27 5.3 1.1 2.4 1 1 1 2 2 2 0 Lipoprotein leucine-zipper TMF_DNA_bd PF12329.8 AAL64328.1 - 6.2 6.9 12.0 16 5.6 12.1 1.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Lectin_N PF03954.14 AAL64328.1 - 7.8 6.3 7.6 16 5.2 7.6 1.5 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain ZapB PF06005.12 AAL64328.1 - 9.5 6.7 11.0 26 5.4 11.0 1.7 1 1 0 1 1 1 0 Cell division protein ZapB Csm1_N PF18504.1 AAL64328.1 - 9.9 6.6 9.0 16 5.9 1.4 2.0 1 1 1 2 2 2 0 Csm1 N-terminal domain CNH PF00780.22 AAL64329.1 - 0.0011 18.7 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 CNH domain Coatomer_WDAD PF04053.14 AAL64329.1 - 0.052 12.6 0.0 0.091 11.8 0.0 1.4 1 0 0 1 1 1 0 Coatomer WD associated region PQQ_2 PF13360.6 AAL64329.1 - 0.079 12.5 0.0 0.33 10.5 0.0 1.9 2 1 0 2 2 2 0 PQQ-like domain TusA PF01206.17 AAL64330.1 - 3.7e-19 68.3 0.0 4.2e-19 68.1 0.0 1.0 1 0 0 1 1 1 1 Sulfurtransferase TusA DUF2249 PF10006.9 AAL64330.1 - 0.056 13.3 0.0 0.18 11.7 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2249) DUF1854 PF08909.11 AAL64330.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1854) DrsE PF02635.15 AAL64331.1 - 6.2e-07 29.8 0.0 7.2e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 DsrE/DsrF-like family DrsE_2 PF13686.6 AAL64331.1 - 0.0034 17.3 0.1 0.0056 16.6 0.1 1.4 1 1 0 1 1 1 1 DsrE/DsrF/DrsH-like family Sulf_transp PF04143.14 AAL64332.1 - 1.5e-40 139.7 37.0 2.1e-25 89.9 10.7 2.5 3 0 0 3 3 3 2 Sulphur transport SieB PF14163.6 AAL64332.1 - 0.48 9.9 3.8 0.15 11.6 0.4 1.9 2 0 0 2 2 2 0 Super-infection exclusion protein B SCO1-SenC PF02630.14 AAL64334.1 - 1.5e-18 67.0 0.0 2.1e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC Rhabdo_ncap PF00945.18 AAL64334.1 - 0.0079 15.1 0.1 0.01 14.7 0.1 1.1 1 0 0 1 1 1 1 Rhabdovirus nucleocapsid protein AhpC-TSA PF00578.21 AAL64334.1 - 0.036 14.0 0.0 0.062 13.2 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family SepRS_C PF18006.1 AAL64334.1 - 0.12 12.5 0.7 0.24 11.5 0.7 1.5 1 0 0 1 1 1 0 O-phosphoseryl-tRNA synthetase C-terminal domain Rrf2 PF02082.20 AAL64335.1 - 7.3e-06 26.2 0.1 3.1e-05 24.2 0.1 1.9 2 0 0 2 2 2 1 Transcriptional regulator HTH_28 PF13518.6 AAL64335.1 - 6.8e-05 22.9 0.2 0.00012 22.2 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_36 PF13730.6 AAL64335.1 - 0.00012 21.9 0.0 0.00022 21.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 AAL64335.1 - 0.00048 19.6 0.0 0.00075 19.0 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 AAL64335.1 - 0.0016 18.3 0.2 0.0025 17.7 0.2 1.4 1 0 0 1 1 1 1 MarR family SgrR_N PF12793.7 AAL64335.1 - 0.0021 18.3 0.0 0.0033 17.6 0.0 1.3 1 0 0 1 1 1 1 Sugar transport-related sRNA regulator N-term HTH_20 PF12840.7 AAL64335.1 - 0.0041 17.2 0.1 0.0081 16.2 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_11 PF08279.12 AAL64335.1 - 0.02 14.9 0.0 0.044 13.7 0.0 1.6 1 0 0 1 1 1 0 HTH domain HxlR PF01638.17 AAL64335.1 - 0.024 14.5 0.0 0.039 13.8 0.0 1.2 1 0 0 1 1 1 0 HxlR-like helix-turn-helix PaaX PF07848.12 AAL64335.1 - 0.031 14.5 0.3 0.068 13.4 0.3 1.5 1 0 0 1 1 1 0 PaaX-like protein HTH_DeoR PF08220.12 AAL64335.1 - 0.031 14.0 0.1 0.062 13.0 0.1 1.5 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain TrmB PF01978.19 AAL64335.1 - 0.071 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_Mga PF08280.11 AAL64335.1 - 0.099 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain CPBP PF02517.16 AAL64336.1 - 1.9e-14 53.8 7.3 1.9e-14 53.8 7.3 2.4 1 1 1 2 2 2 1 CPBP intramembrane metalloprotease Radical_SAM PF04055.21 AAL64337.1 - 1e-17 65.0 0.0 6.9e-17 62.3 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily AP_endonuc_2 PF01261.24 AAL64337.1 - 0.061 12.8 0.0 6.5 6.1 0.0 3.1 2 2 1 3 3 3 0 Xylose isomerase-like TIM barrel E1_dh PF00676.20 AAL64338.1 - 1.3e-70 237.7 0.0 1.5e-70 237.5 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 AAL64338.1 - 0.0076 16.0 0.4 0.028 14.2 0.4 1.9 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 AAL64338.1 - 0.038 13.2 0.0 0.059 12.6 0.0 1.2 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.24 AAL64339.1 - 1.2e-52 178.2 0.0 1.7e-52 177.7 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 AAL64339.1 - 6.8e-35 119.7 1.1 1.4e-34 118.6 0.5 1.8 2 0 0 2 2 2 1 Transketolase, C-terminal domain 2-oxoacid_dh PF00198.23 AAL64340.1 - 8e-85 284.0 0.0 9.9e-85 283.7 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 AAL64340.1 - 4.4e-21 74.5 1.2 4.4e-21 74.5 1.2 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 AAL64340.1 - 3e-17 62.7 1.9 1.8e-16 60.2 0.8 2.5 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 AAL64340.1 - 3e-13 49.3 0.2 2.9e-06 27.0 0.1 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 AAL64340.1 - 2.9e-06 27.9 0.7 0.012 16.2 0.1 2.5 1 1 1 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 AAL64340.1 - 6.1e-05 22.3 1.1 0.022 14.0 0.1 2.6 2 1 1 3 3 3 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion PTS_EIIA_1 PF00358.20 AAL64340.1 - 0.00021 21.0 0.5 0.14 12.0 0.0 2.9 2 1 1 3 3 3 2 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 DUF2118 PF09891.9 AAL64340.1 - 0.0074 16.2 0.5 0.026 14.5 0.5 2.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2118) RnfC_N PF13375.6 AAL64340.1 - 0.014 15.3 0.2 0.051 13.5 0.2 2.0 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain PYNP_C PF07831.13 AAL64340.1 - 0.032 13.9 1.3 1.1 9.0 0.0 2.7 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain NQRA PF05896.11 AAL64340.1 - 0.036 13.5 0.6 0.15 11.5 0.6 1.9 1 1 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) QRPTase_N PF02749.16 AAL64340.1 - 0.037 14.1 0.3 11 6.2 0.0 2.9 1 1 1 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain Pyr_redox_2 PF07992.14 AAL64341.1 - 6e-69 232.5 0.1 8e-69 232.1 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 AAL64341.1 - 3.8e-32 110.8 0.1 6.8e-32 110.0 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 AAL64341.1 - 3.2e-24 85.3 6.0 2e-18 66.7 0.1 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAL64341.1 - 2.8e-18 66.2 0.0 5.3e-18 65.3 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AAL64341.1 - 5e-11 41.9 5.6 2.3e-05 23.3 0.6 3.5 4 0 0 4 4 4 3 HI0933-like protein GIDA PF01134.22 AAL64341.1 - 7.2e-11 41.8 4.2 2e-07 30.5 0.6 3.6 4 0 0 4 4 4 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 AAL64341.1 - 2.1e-10 40.7 2.5 2.4e-06 27.7 0.1 3.3 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 AAL64341.1 - 1.1e-08 34.9 0.3 1.1e-08 34.9 0.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AAL64341.1 - 4.4e-08 32.6 8.2 4.8e-07 29.2 0.3 3.3 3 0 0 3 3 3 1 FAD binding domain FAD_binding_3 PF01494.19 AAL64341.1 - 7.1e-08 32.1 11.1 0.0074 15.6 1.3 3.9 4 0 0 4 4 4 3 FAD binding domain AlaDh_PNT_C PF01262.21 AAL64341.1 - 9.9e-08 31.5 0.7 0.0051 16.1 0.2 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 AAL64341.1 - 6.7e-06 25.2 7.6 4.1e-05 22.6 0.1 3.0 4 0 0 4 4 4 2 Tryptophan halogenase DAO PF01266.24 AAL64341.1 - 7e-06 25.9 11.9 0.0013 18.4 1.4 4.0 3 1 0 4 4 4 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 AAL64341.1 - 7.8e-06 25.2 7.2 0.0098 15.0 0.2 3.3 3 0 0 3 3 3 3 Lycopene cyclase protein 3HCDH_N PF02737.18 AAL64341.1 - 8.3e-06 25.8 1.1 0.00068 19.6 0.2 2.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 AAL64341.1 - 0.0028 18.1 0.8 1.5 9.3 0.1 2.7 3 0 0 3 3 2 1 Putative NAD(P)-binding NAD_binding_9 PF13454.6 AAL64341.1 - 0.0032 17.5 3.9 2.4 8.1 0.1 3.8 4 0 0 4 4 4 1 FAD-NAD(P)-binding XdhC_C PF13478.6 AAL64341.1 - 0.026 15.0 0.1 3.4 8.2 0.0 2.5 2 0 0 2 2 2 0 XdhC Rossmann domain Thi4 PF01946.17 AAL64341.1 - 0.048 12.9 1.9 0.74 9.0 0.1 2.5 2 0 0 2 2 2 0 Thi4 family DFP PF04127.15 AAL64341.1 - 0.12 12.2 0.2 12 5.7 0.0 2.3 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein 2-Hacid_dh_C PF02826.19 AAL64341.1 - 0.14 11.5 0.3 3.3 7.0 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K_oxygenase PF13434.6 AAL64341.1 - 0.42 9.7 0.8 3.5 6.7 0.6 2.5 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) BPL_LplA_LipB PF03099.19 AAL64342.1 - 1.8e-08 34.4 0.3 2.7e-08 33.8 0.3 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family TusA PF01206.17 AAL64343.1 - 0.00023 20.9 0.0 0.00031 20.5 0.0 1.2 1 0 0 1 1 1 1 Sulfurtransferase TusA HTH_36 PF13730.6 AAL64344.1 - 9.8e-05 22.2 0.0 0.00031 20.6 0.0 1.9 2 1 0 2 2 2 1 Helix-turn-helix domain Rrf2 PF02082.20 AAL64344.1 - 0.00037 20.8 0.0 0.0016 18.7 0.0 1.9 2 0 0 2 2 2 1 Transcriptional regulator TrmB PF01978.19 AAL64344.1 - 0.00045 20.0 0.0 0.001 18.9 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB DUF2250 PF10007.9 AAL64344.1 - 0.00065 19.8 0.1 0.0025 17.9 0.0 1.8 1 1 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2250) HTH_20 PF12840.7 AAL64344.1 - 0.0015 18.5 0.0 0.0025 17.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain TFIIE_alpha PF02002.17 AAL64344.1 - 0.0033 17.3 0.0 0.0072 16.2 0.0 1.6 1 0 0 1 1 1 1 TFIIE alpha subunit PaaX PF07848.12 AAL64344.1 - 0.0036 17.5 0.1 0.0084 16.3 0.1 1.6 1 0 0 1 1 1 1 PaaX-like protein MarR_2 PF12802.7 AAL64344.1 - 0.0057 16.5 0.0 0.016 15.1 0.0 1.7 2 0 0 2 2 2 1 MarR family Penicillinase_R PF03965.16 AAL64344.1 - 0.013 15.8 0.0 0.021 15.1 0.0 1.3 1 0 0 1 1 1 0 Penicillinase repressor RP-C PF03428.13 AAL64344.1 - 0.019 14.6 0.1 0.03 14.0 0.1 1.3 1 0 0 1 1 1 0 Replication protein C N-terminal domain HTH_DeoR PF08220.12 AAL64344.1 - 0.019 14.7 0.1 0.037 13.8 0.1 1.4 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Methyltransf_23 PF13489.6 AAL64344.1 - 0.031 14.1 0.0 0.051 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain HTH_5 PF01022.20 AAL64344.1 - 0.053 13.4 0.0 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_Crp_2 PF13545.6 AAL64344.1 - 0.068 13.2 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Pirin PF02678.16 AAL64345.1 - 2.9e-36 123.7 0.0 4.3e-36 123.2 0.0 1.3 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 AAL64345.1 - 6.9e-29 100.3 0.0 5e-28 97.5 0.0 2.0 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 AAL64345.1 - 0.00025 20.7 0.2 0.00056 19.6 0.2 1.6 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 AAL64345.1 - 0.03 14.0 0.0 0.083 12.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF861) FdhE PF04216.12 AAL64347.1 - 0.016 15.1 2.7 0.023 14.6 2.7 1.1 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation zf-TFIIB PF13453.6 AAL64347.1 - 0.019 14.3 0.6 0.019 14.3 0.6 1.8 2 0 0 2 2 2 0 Transcription factor zinc-finger Zn_Tnp_IS1595 PF12760.7 AAL64347.1 - 0.022 14.7 5.8 0.03 14.3 4.4 2.0 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_4 PF13717.6 AAL64347.1 - 0.032 14.2 0.6 1.8 8.6 0.0 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zf-IS66 PF13005.7 AAL64347.1 - 0.18 12.2 4.3 14 6.2 0.1 3.6 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 zf-HIT PF04438.16 AAL64347.1 - 0.26 11.2 10.8 6.1 6.8 3.2 3.4 3 0 0 3 3 3 0 HIT zinc finger Lar_restr_allev PF14354.6 AAL64347.1 - 0.26 11.7 4.7 11 6.5 4.7 2.4 1 1 0 1 1 1 0 Restriction alleviation protein Lar ADK_lid PF05191.14 AAL64347.1 - 2.2 8.3 4.7 76 3.4 0.0 3.5 3 0 0 3 3 3 0 Adenylate kinase, active site lid zf-RanBP PF00641.18 AAL64347.1 - 4.2 6.8 10.0 0.2 11.0 0.6 2.8 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others A2L_zn_ribbon PF08792.10 AAL64347.1 - 5.7 6.8 6.8 29 4.5 0.3 3.3 3 0 0 3 3 3 0 A2L zinc ribbon domain Ni_hydr_CYTB PF01292.20 AAL64348.1 - 1.2e-16 60.9 12.5 1.4e-16 60.6 12.5 1.1 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 SUR7 PF06687.12 AAL64348.1 - 0.038 13.6 5.6 1.2 8.7 0.0 3.0 1 1 2 3 3 3 0 SUR7/PalI family DUF4405 PF14358.6 AAL64348.1 - 0.046 14.3 10.7 0.046 14.3 10.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) Fer4_11 PF13247.6 AAL64349.1 - 6.3e-22 77.6 10.4 6.3e-22 77.6 10.4 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AAL64349.1 - 9.9e-18 64.5 16.1 3.4e-09 37.1 0.1 3.9 1 1 3 4 4 4 4 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAL64349.1 - 3.7e-13 49.4 20.9 3e-06 27.3 9.5 3.0 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 AAL64349.1 - 1.3e-12 47.0 45.7 2.2e-07 30.4 6.4 5.4 6 0 0 6 6 6 4 4Fe-4S binding domain Fer4_10 PF13237.6 AAL64349.1 - 2.9e-11 43.3 28.6 6.5e-07 29.4 11.2 3.5 2 1 1 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.7 AAL64349.1 - 8.1e-09 35.2 44.9 6.5e-05 22.8 4.8 4.7 5 0 0 5 5 5 4 4Fe-4S binding domain Fer4_8 PF13183.6 AAL64349.1 - 7.8e-08 32.7 22.6 5.3e-06 26.8 1.9 3.6 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAL64349.1 - 1.5e-07 31.1 39.7 0.00021 21.2 2.5 4.5 4 1 0 4 4 4 3 4Fe-4S binding domain Fer4_21 PF14697.6 AAL64349.1 - 2.4e-07 30.8 28.9 4.6e-05 23.5 10.9 3.4 4 0 0 4 4 3 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 AAL64349.1 - 8e-07 29.6 42.8 0.053 14.5 4.0 4.3 4 0 0 4 4 4 4 4Fe-4S binding domain Fer4_4 PF12800.7 AAL64349.1 - 2.1e-06 27.8 35.9 0.001 19.4 3.6 4.5 5 0 0 5 5 4 3 4Fe-4S binding domain Fer4_16 PF13484.6 AAL64349.1 - 3.6e-06 27.8 27.7 0.23 12.4 2.9 4.7 3 1 3 6 6 6 4 4Fe-4S double cluster binding domain Fer4_15 PF13459.6 AAL64349.1 - 9.1e-05 23.1 19.7 0.22 12.3 1.7 4.1 3 1 0 3 3 3 3 4Fe-4S single cluster domain Fer4_17 PF13534.6 AAL64349.1 - 0.0039 17.7 28.9 0.93 10.1 1.0 4.5 3 2 0 3 3 3 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 AAL64349.1 - 0.45 11.1 33.4 3 8.4 4.8 4.7 3 2 1 4 4 4 0 4Fe-4S single cluster domain of Ferredoxin I SCIFF PF13165.6 AAL64349.1 - 2.5 8.1 12.5 1.2 9.2 0.3 3.2 3 0 0 3 3 3 0 Six-cysteine peptide SCIFF Fer4_22 PF17179.4 AAL64349.1 - 2.7 8.9 21.2 0.27 12.1 2.2 4.1 3 1 1 4 4 4 0 4Fe-4S dicluster domain Molybdopterin PF00384.22 AAL64350.1 - 2.6e-44 151.9 0.0 1.2e-42 146.4 0.0 3.3 2 1 0 2 2 2 1 Molybdopterin oxidoreductase Molybdop_Fe4S4 PF04879.16 AAL64350.1 - 4.8e-16 58.5 0.1 9.6e-16 57.5 0.1 1.5 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain Molydop_binding PF01568.21 AAL64350.1 - 1.1e-09 38.3 0.0 2.9e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain MazE_antitoxin PF04014.18 AAL64350.1 - 0.00046 20.0 0.1 0.26 11.2 0.0 3.6 3 0 0 3 3 3 1 Antidote-toxin recognition MazE, bacterial antitoxin TAT_signal PF10518.9 AAL64350.1 - 0.4 10.6 3.2 1 9.3 3.2 1.7 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence FdhD-NarQ PF02634.15 AAL64351.1 - 4.8e-26 91.9 0.3 2e-25 89.9 0.3 1.7 1 1 0 1 1 1 1 FdhD/NarQ family TrmB PF01978.19 AAL64352.1 - 8.9e-07 28.7 0.4 1.5e-06 28.0 0.4 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.10 AAL64352.1 - 0.00031 20.5 0.7 0.0025 17.6 0.0 2.5 2 1 0 2 2 2 1 IclR helix-turn-helix domain MarR PF01047.22 AAL64352.1 - 0.003 17.4 0.0 0.0065 16.4 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_5 PF01022.20 AAL64352.1 - 0.004 17.0 0.0 0.0091 15.8 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_27 PF13463.6 AAL64352.1 - 0.011 16.2 0.1 0.041 14.4 0.0 1.8 2 0 0 2 2 2 0 Winged helix DNA-binding domain GntR PF00392.21 AAL64352.1 - 0.012 15.3 0.0 0.035 13.8 0.0 1.9 1 1 0 1 1 1 0 Bacterial regulatory proteins, gntR family MarR_2 PF12802.7 AAL64352.1 - 0.025 14.5 0.1 0.087 12.7 0.0 1.9 2 0 0 2 2 2 0 MarR family PadR PF03551.14 AAL64352.1 - 0.027 14.4 0.1 0.053 13.5 0.1 1.5 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Fe_dep_repress PF01325.19 AAL64352.1 - 0.053 13.7 0.2 0.11 12.7 0.2 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_24 PF13412.6 AAL64352.1 - 0.063 12.8 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 AAL64352.1 - 0.064 13.1 0.1 0.92 9.4 0.0 2.3 2 0 0 2 2 2 0 Homeodomain-like domain DUF2513 PF10711.9 AAL64352.1 - 0.069 13.4 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 Hypothetical protein (DUF2513) HTH_20 PF12840.7 AAL64352.1 - 0.12 12.4 0.4 0.43 10.7 0.0 2.0 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_11 PF08279.12 AAL64352.1 - 0.16 12.0 0.0 0.38 10.7 0.0 1.7 1 0 0 1 1 1 0 HTH domain CoA_binding_2 PF13380.6 AAL64353.1 - 3e-33 114.7 0.1 3.4e-33 114.6 0.1 1.0 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 AAL64353.1 - 0.0014 19.2 0.0 0.0026 18.4 0.0 1.4 1 0 0 1 1 1 1 CoA binding domain XdhC_C PF13478.6 AAL64354.1 - 3.6e-23 82.4 0.6 5.1e-23 81.9 0.6 1.2 1 0 0 1 1 1 1 XdhC Rossmann domain 2-Hacid_dh_C PF02826.19 AAL64354.1 - 0.064 12.6 0.0 0.098 12.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PaREP1 PF05942.11 AAL64355.1 - 2.1e-25 88.9 3.0 2.4e-25 88.7 3.0 1.0 1 0 0 1 1 1 1 Archaeal PaREP1/PaREP8 family GH114_assoc PF14741.6 AAL64355.1 - 0.1 12.8 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 N-terminal glycosyl-hydrolase-114-associated domain Diphthami_syn_2 PF01902.17 AAL64356.1 - 6.3e-57 192.6 0.0 7.1e-57 192.4 0.0 1.0 1 0 0 1 1 1 1 Diphthamide synthase BON PF04972.17 AAL64356.1 - 0.14 12.5 0.1 0.35 11.2 0.1 1.6 1 0 0 1 1 1 0 BON domain PaREP1 PF05942.11 AAL64357.1 - 1.8e-25 89.1 3.9 2.3e-25 88.8 3.9 1.1 1 0 0 1 1 1 1 Archaeal PaREP1/PaREP8 family EF-hand_9 PF14658.6 AAL64357.1 - 0.1 13.0 0.0 3.1 8.2 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain GH114_assoc PF14741.6 AAL64357.1 - 0.13 12.5 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 N-terminal glycosyl-hydrolase-114-associated domain PIN PF01850.21 AAL64358.1 - 1e-08 35.7 0.0 1.1e-08 35.6 0.0 1.1 1 0 0 1 1 1 1 PIN domain RHH_6 PF16762.5 AAL64359.1 - 0.037 14.6 0.0 0.055 14.1 0.0 1.3 1 0 0 1 1 1 0 Ribbon-helix-helix domain MarR_2 PF12802.7 AAL64360.1 - 2.9e-11 43.1 0.7 1.3e-09 37.8 0.1 2.7 2 1 1 3 3 3 1 MarR family TrmB PF01978.19 AAL64360.1 - 1.2e-10 41.1 0.4 3.3e-09 36.5 0.2 2.6 2 1 1 3 3 3 1 Sugar-specific transcriptional regulator TrmB HTH_27 PF13463.6 AAL64360.1 - 1.8e-10 41.2 0.6 3e-09 37.3 0.1 2.3 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_5 PF01022.20 AAL64360.1 - 2.4e-08 33.7 0.6 1.8e-07 30.9 0.1 2.6 3 0 0 3 3 3 1 Bacterial regulatory protein, arsR family Fe_dep_repress PF01325.19 AAL64360.1 - 4.5e-07 30.0 0.6 9.5e-07 28.9 0.1 1.8 2 0 0 2 2 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_24 PF13412.6 AAL64360.1 - 6.7e-07 28.8 0.9 1.2e-05 24.7 0.1 2.4 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_34 PF13601.6 AAL64360.1 - 7.2e-07 29.3 0.1 1.3e-06 28.5 0.1 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_IclR PF09339.10 AAL64360.1 - 1.1e-06 28.3 0.6 8.6e-06 25.5 0.2 2.6 2 1 0 2 2 2 1 IclR helix-turn-helix domain MarR PF01047.22 AAL64360.1 - 3e-06 27.0 0.1 3.5e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 MarR family HTH_20 PF12840.7 AAL64360.1 - 4.9e-05 23.3 0.1 0.00023 21.1 0.1 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain Rrf2 PF02082.20 AAL64360.1 - 0.00032 21.0 1.0 0.0053 17.1 0.3 2.5 1 1 1 3 3 3 1 Transcriptional regulator HTH_36 PF13730.6 AAL64360.1 - 0.0004 20.3 1.2 0.0021 18.0 0.1 2.5 2 1 1 3 3 3 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 AAL64360.1 - 0.0027 17.7 0.1 0.036 14.0 0.1 2.3 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_11 PF08279.12 AAL64360.1 - 0.003 17.5 0.1 0.0066 16.4 0.1 1.5 1 0 0 1 1 1 1 HTH domain HTH_28 PF13518.6 AAL64360.1 - 0.0034 17.5 0.7 0.2 11.8 0.1 3.1 3 0 0 3 3 3 1 Helix-turn-helix domain FeoC PF09012.10 AAL64360.1 - 0.0049 16.9 0.1 0.021 14.9 0.0 1.9 2 0 0 2 2 2 1 FeoC like transcriptional regulator HTH_45 PF14947.6 AAL64360.1 - 0.0057 16.6 0.0 0.037 14.0 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn-helix HTH_Tnp_ISL3 PF13542.6 AAL64360.1 - 0.017 14.5 0.1 0.049 13.1 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_1 PF00126.27 AAL64360.1 - 0.02 14.9 2.4 0.072 13.0 0.8 2.4 1 1 1 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_23 PF13384.6 AAL64360.1 - 0.025 14.4 1.0 0.085 12.7 0.1 2.3 3 0 0 3 3 3 0 Homeodomain-like domain HTH_9 PF08221.11 AAL64360.1 - 0.026 14.6 0.2 0.094 12.8 0.0 1.9 3 0 0 3 3 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain FtsK_gamma PF09397.10 AAL64360.1 - 0.026 14.3 0.6 0.084 12.7 0.3 1.9 2 0 0 2 2 2 0 Ftsk gamma domain DUF1495 PF07381.11 AAL64360.1 - 0.026 14.3 0.1 0.15 11.9 0.1 2.2 2 1 0 2 2 1 0 Winged helix DNA-binding domain (DUF1495) HTH_DeoR PF08220.12 AAL64360.1 - 0.036 13.8 0.0 0.086 12.6 0.0 1.7 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_38 PF13936.6 AAL64360.1 - 0.041 13.6 0.3 0.39 10.5 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain GntR PF00392.21 AAL64360.1 - 0.05 13.3 0.2 0.12 12.1 0.2 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_AsnC-type PF13404.6 AAL64360.1 - 0.093 12.6 1.0 0.39 10.6 0.1 2.3 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain LexA_DNA_bind PF01726.16 AAL64360.1 - 0.13 12.0 0.1 0.38 10.6 0.1 1.8 2 1 0 2 2 1 0 LexA DNA binding domain Hemerythrin PF01814.23 AAL64361.1 - 6.5e-19 68.9 0.1 1.3e-18 67.9 0.0 1.4 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain FTO_CTD PF12934.7 AAL64361.1 - 0.3 10.8 3.8 2 8.1 0.8 2.3 1 1 1 2 2 2 0 FTO C-terminal domain DUF2981 PF11200.8 AAL64362.1 - 0.6 9.8 3.6 0.66 9.7 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) MarR PF01047.22 AAL64363.1 - 5e-08 32.8 0.4 2.2e-07 30.7 0.1 2.1 2 0 0 2 2 2 1 MarR family TrmB PF01978.19 AAL64363.1 - 3.6e-05 23.6 0.2 6.3e-05 22.8 0.0 1.5 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 AAL64363.1 - 7.6e-05 22.5 0.4 0.00023 21.0 0.3 1.8 1 1 1 2 2 2 1 MarR family Fe_dep_repress PF01325.19 AAL64363.1 - 0.0011 19.1 0.1 0.0024 18.1 0.0 1.7 2 0 0 2 2 2 1 Iron dependent repressor, N-terminal DNA binding domain HTH_20 PF12840.7 AAL64363.1 - 0.0047 16.9 1.6 0.011 15.7 1.6 1.7 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.10 AAL64363.1 - 0.0072 16.1 0.6 0.027 14.2 0.2 2.0 1 1 1 2 2 2 1 IclR helix-turn-helix domain DUF4423 PF14394.6 AAL64363.1 - 0.01 15.6 0.4 0.016 14.9 0.1 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) HTH_27 PF13463.6 AAL64363.1 - 0.022 15.3 0.8 0.042 14.3 0.4 1.7 1 1 1 2 2 2 0 Winged helix DNA-binding domain HTH_Crp_2 PF13545.6 AAL64363.1 - 0.034 14.1 0.3 0.13 12.2 0.0 1.8 1 1 0 2 2 2 0 Crp-like helix-turn-helix domain Penicillinase_R PF03965.16 AAL64363.1 - 0.043 14.2 0.3 0.085 13.2 0.2 1.6 1 1 1 2 2 2 0 Penicillinase repressor LexA_DNA_bind PF01726.16 AAL64363.1 - 0.048 13.4 0.1 0.21 11.4 0.0 2.1 1 1 1 2 2 2 0 LexA DNA binding domain DUF4364 PF14277.6 AAL64363.1 - 0.064 13.0 0.0 0.088 12.5 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4364) HTH_29 PF13551.6 AAL64363.1 - 0.065 13.3 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix HTH_24 PF13412.6 AAL64363.1 - 0.069 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF3116 PF11313.8 AAL64363.1 - 0.16 11.8 0.0 0.21 11.5 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3116) Glyoxalase PF00903.25 AAL64364.1 - 3.7e-13 49.8 0.0 7.8e-07 29.3 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 AAL64364.1 - 0.00083 19.6 0.1 0.46 10.8 0.1 3.1 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 AAL64364.1 - 0.0088 16.2 0.2 4.6 7.3 0.0 2.7 2 1 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_6 PF18029.1 AAL64364.1 - 0.016 16.0 0.0 0.17 12.7 0.0 2.3 1 1 1 2 2 2 0 Glyoxalase-like domain TPR_7 PF13176.6 AAL64364.1 - 0.17 12.0 0.1 8 6.8 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Haem_degrading PF03928.14 AAL64365.1 - 3.6e-24 85.1 0.6 4e-24 85.0 0.6 1.0 1 0 0 1 1 1 1 Haem-degrading ADH_N PF08240.12 AAL64366.1 - 5.8e-27 93.7 1.4 9e-27 93.1 1.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AAL64366.1 - 1.4e-18 67.1 0.2 3e-18 66.1 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AAL64366.1 - 7.7e-16 59.4 0.1 1.5e-15 58.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 AAL64366.1 - 4.2e-05 23.4 0.0 0.0001 22.2 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase AlaDh_PNT_C PF01262.21 AAL64366.1 - 0.0036 16.6 0.2 0.0068 15.7 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.21 AAL64366.1 - 0.0052 16.5 0.1 0.008 15.9 0.1 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_10 PF13460.6 AAL64366.1 - 0.055 13.4 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H-binding NmrA PF05368.13 AAL64366.1 - 0.095 12.2 0.6 0.56 9.7 0.2 2.1 2 0 0 2 2 2 0 NmrA-like family 2-Hacid_dh_C PF02826.19 AAL64366.1 - 0.13 11.6 0.1 0.52 9.6 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DapB_N PF01113.20 AAL64366.1 - 0.13 12.3 0.7 1 9.5 0.1 2.4 1 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 AAL64366.1 - 6.7 7.2 5.6 0.98 9.9 1.3 1.9 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain FAA_hydrolase PF01557.18 AAL64367.1 - 7.3e-68 228.5 0.0 9.1e-68 228.2 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family GSDH PF07995.11 AAL64368.1 - 6.4e-87 291.9 0.0 8.6e-87 291.5 0.0 1.1 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase Fer2_3 PF13085.6 AAL64369.1 - 3.6e-26 91.3 0.1 4.8e-26 90.9 0.1 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.27 AAL64369.1 - 5e-07 29.6 0.3 1.2e-06 28.4 0.3 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 AAL64369.1 - 0.015 15.3 0.4 0.028 14.5 0.1 1.7 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain DHODB_Fe-S_bind PF10418.9 AAL64369.1 - 0.017 14.9 3.9 0.042 13.7 3.9 1.6 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B CBS PF00571.28 AAL64370.1 - 1.3e-23 83.2 3.8 4.3e-11 43.1 0.6 2.1 2 0 0 2 2 2 2 CBS domain Ribosomal_L9_C PF03948.14 AAL64370.1 - 5.4e-05 23.6 0.1 0.26 11.8 0.0 2.4 2 0 0 2 2 2 2 Ribosomal protein L9, C-terminal domain HpaB_N PF11794.8 AAL64371.1 - 1.3e-99 333.3 0.1 1.7e-99 332.9 0.1 1.2 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal HpaB PF03241.13 AAL64371.1 - 6.2e-66 221.3 0.0 9.3e-66 220.8 0.0 1.3 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase C terminal Acyl-CoA_dh_1 PF00441.24 AAL64371.1 - 0.0015 18.8 0.0 0.0029 17.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 AAL64371.1 - 0.0032 17.6 0.0 0.0066 16.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain DrsE_2 PF13686.6 AAL64372.1 - 2.9e-07 30.5 0.0 3.7e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 DsrE/DsrF/DrsH-like family DrsE PF02635.15 AAL64372.1 - 0.00072 19.9 0.0 0.0017 18.7 0.0 1.6 1 1 0 1 1 1 1 DsrE/DsrF-like family Mn_catalase PF05067.12 AAL64373.1 - 9e-80 267.7 0.0 1e-79 267.5 0.0 1.0 1 0 0 1 1 1 1 Manganese containing catalase Ferritin-like PF12902.7 AAL64373.1 - 0.051 13.4 0.0 0.082 12.8 0.0 1.3 1 0 0 1 1 1 0 Ferritin-like NADH-u_ox-rdase PF10785.9 AAL64374.1 - 2.6 8.8 5.0 1.5e+02 3.2 5.0 2.6 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit ABC_tran PF00005.27 AAL64375.1 - 9.7e-28 97.4 0.0 1.3e-27 97.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAL64375.1 - 0.00046 20.1 1.1 0.14 11.9 0.4 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AAL64375.1 - 0.001 18.7 0.1 0.002 17.9 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AAL64375.1 - 0.016 15.2 0.1 0.028 14.3 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 AAL64375.1 - 0.02 15.3 0.5 0.036 14.4 0.5 1.6 1 1 0 1 1 1 0 AAA ATPase domain SbcCD_C PF13558.6 AAL64375.1 - 0.044 14.0 0.1 0.42 10.9 0.1 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit TsaE PF02367.17 AAL64375.1 - 0.1 12.6 0.2 0.18 11.8 0.2 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Phosphonate-bd PF12974.7 AAL64376.1 - 1.2e-34 120.0 0.0 1.5e-34 119.6 0.0 1.1 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 AAL64376.1 - 0.00024 20.6 0.0 0.13 11.7 0.0 2.3 1 1 1 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 Transferrin PF00405.17 AAL64376.1 - 0.015 14.5 0.0 0.022 13.9 0.0 1.4 1 0 0 1 1 1 0 Transferrin Ferritin PF00210.24 AAL64377.1 - 3.2e-25 88.7 0.2 3.9e-25 88.5 0.2 1.0 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 AAL64377.1 - 2.9e-08 34.2 3.0 0.0037 17.7 0.3 2.0 2 0 0 2 2 2 2 Rubrerythrin Ferritin_2 PF13668.6 AAL64377.1 - 2e-05 24.8 0.1 4.7e-05 23.6 0.1 1.5 1 1 0 1 1 1 1 Ferritin-like domain COQ7 PF03232.13 AAL64377.1 - 0.0027 17.5 0.2 0.97 9.2 0.1 2.0 2 0 0 2 2 2 2 Ubiquinone biosynthesis protein COQ7 Sigma70_r3 PF04539.16 AAL64377.1 - 0.2 11.8 1.4 0.34 11.0 0.1 2.0 2 0 0 2 2 2 0 Sigma-70 region 3 Nitro_FeMo-Co PF02579.17 AAL64378.1 - 9.3e-08 32.3 0.0 5e-05 23.6 0.0 2.1 1 1 0 1 1 1 1 Dinitrogenase iron-molybdenum cofactor Glyoxal_oxid_N PF07250.11 AAL64378.1 - 0.079 12.1 0.0 0.096 11.9 0.0 1.1 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus DAO PF01266.24 AAL64379.1 - 1.7e-34 120.0 0.2 2.1e-34 119.6 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 AAL64379.1 - 2.4e-06 27.0 0.2 0.0019 17.5 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AAL64379.1 - 3.3e-06 27.2 0.5 9e-06 25.8 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 AAL64379.1 - 0.00036 19.9 0.1 0.00051 19.4 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 AAL64379.1 - 0.00056 19.1 0.1 0.55 9.2 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_binding_2 PF00890.24 AAL64379.1 - 0.00078 18.6 0.2 0.0014 17.8 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 AAL64379.1 - 0.00088 19.8 0.3 0.0026 18.3 0.3 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 AAL64379.1 - 0.0056 16.3 0.1 0.01 15.5 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 AAL64379.1 - 0.0086 14.8 0.1 0.012 14.4 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 AAL64379.1 - 0.0093 15.2 0.2 0.018 14.3 0.1 1.5 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 AAL64379.1 - 0.01 15.2 0.1 0.015 14.7 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 AAL64379.1 - 0.012 16.1 0.1 0.018 15.4 0.1 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding GIDA PF01134.22 AAL64379.1 - 0.014 14.5 1.8 0.096 11.7 0.7 2.4 3 0 0 3 3 3 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 AAL64379.1 - 0.026 13.4 0.2 0.038 12.9 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase UDPG_MGDP_dh_N PF03721.14 AAL64379.1 - 0.077 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 AAL64379.1 - 0.089 12.1 0.2 0.14 11.4 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 AAL64379.1 - 0.095 11.9 0.0 0.6 9.3 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UPF0086 PF01868.16 AAL64380.1 - 0.00022 21.1 0.8 0.00026 20.8 0.5 1.3 1 1 0 1 1 1 1 Domain of unknown function UPF0086 Fer4 PF00037.27 AAL64381.1 - 1.6e-10 40.4 12.3 3.3e-07 29.8 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 AAL64381.1 - 5.7e-09 35.7 11.8 8.9e-06 25.6 3.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 AAL64381.1 - 4.8e-08 33.8 2.9 0.0015 19.5 1.3 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 AAL64381.1 - 8.4e-08 32.7 19.9 3.8e-05 24.2 9.1 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAL64381.1 - 1.1e-06 28.7 3.3 2.1e-06 27.8 3.3 1.4 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAL64381.1 - 1.2e-06 28.2 8.4 0.00011 22.1 3.0 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 AAL64381.1 - 6.3e-06 26.2 6.5 0.0001 22.3 7.4 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 AAL64381.1 - 8e-06 25.9 4.1 1.2e-05 25.4 4.1 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAL64381.1 - 0.00014 22.3 5.1 0.0043 17.6 0.6 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 AAL64381.1 - 0.00027 21.2 3.2 0.00027 21.2 3.2 2.5 2 1 0 2 2 2 1 4Fe-4S binding domain Fer4_3 PF12798.7 AAL64381.1 - 0.0007 20.4 13.3 0.037 15.0 5.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 AAL64381.1 - 0.0029 18.0 8.6 1 9.8 8.6 2.3 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_13 PF13370.6 AAL64381.1 - 0.024 15.2 2.1 0.024 15.2 2.1 2.3 2 1 1 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 AAL64381.1 - 0.035 14.3 6.6 0.34 11.1 1.4 2.1 1 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 AAL64381.1 - 0.096 13.4 1.0 0.096 13.4 1.0 2.8 1 1 2 3 3 3 0 4Fe-4S single cluster domain Fer4_22 PF17179.4 AAL64381.1 - 0.17 12.7 2.9 1.5 9.7 1.6 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain TusA PF01206.17 AAL64384.1 - 8.8e-17 60.7 0.0 9.7e-17 60.6 0.0 1.0 1 0 0 1 1 1 1 Sulfurtransferase TusA DrsE_2 PF13686.6 AAL64385.1 - 5.4e-28 97.8 0.5 1.1e-14 54.6 0.1 2.0 1 1 1 2 2 2 2 DsrE/DsrF/DrsH-like family DrsE PF02635.15 AAL64385.1 - 1.5e-11 44.7 0.0 2.4e-11 44.0 0.0 1.4 1 1 0 1 1 1 1 DsrE/DsrF-like family Pterin_4a PF01329.19 AAL64386.1 - 1.6e-17 63.5 0.0 1.9e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Cation_efflux PF01545.21 AAL64387.1 - 1.1e-31 110.2 23.1 1.3e-31 109.9 23.1 1.0 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 AAL64387.1 - 0.00029 20.9 0.4 0.00053 20.1 0.4 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter PaREP1 PF05942.11 AAL64388.1 - 2.3e-31 108.1 1.6 2.8e-31 107.8 0.1 1.7 2 0 0 2 2 2 1 Archaeal PaREP1/PaREP8 family Thioredox_DsbH PF03190.15 AAL64389.1 - 8.9e-60 201.3 0.0 1.4e-59 200.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 AAL64389.1 - 1.1e-14 54.4 0.1 1.8e-14 53.7 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 AAL64389.1 - 0.00027 21.4 0.0 0.00053 20.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.20 AAL64389.1 - 0.0054 16.7 0.2 0.011 15.8 0.2 1.4 1 0 0 1 1 1 1 Thioredoxin C5-epim_C PF06662.13 AAL64389.1 - 0.026 14.0 2.4 1.4 8.4 0.1 3.1 3 1 0 3 3 3 0 D-glucuronyl C5-epimerase C-terminus PaREP1 PF05942.11 AAL64390.1 - 2.4e-16 59.7 0.2 3.3e-16 59.2 0.2 1.2 1 0 0 1 1 1 1 Archaeal PaREP1/PaREP8 family TPR_20 PF14561.6 AAL64390.1 - 0.0052 17.1 2.0 0.0064 16.8 0.8 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat Mdv1 PF11542.8 AAL64390.1 - 0.08 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial division protein 1 Endonuc_Holl PF10107.9 AAL64394.1 - 6.5e-61 204.9 4.3 1.1e-60 204.1 4.3 1.3 1 0 0 1 1 1 1 Endonuclease related to archaeal Holliday junction resolvase UPF0102 PF02021.17 AAL64394.1 - 0.037 14.2 1.5 0.065 13.5 0.0 2.3 2 2 0 2 2 2 0 Uncharacterised protein family UPF0102 Thump_like PF18096.1 AAL64394.1 - 0.095 12.6 1.9 0.22 11.5 1.9 1.7 1 0 0 1 1 1 0 THUMP domain-like PIN_8 PF18476.1 AAL64394.1 - 0.11 12.3 2.8 0.082 12.7 0.8 1.6 2 0 0 2 2 2 0 PIN like domain SBP56 PF05694.11 AAL64395.1 - 5.9e-200 664.9 0.0 6.7e-200 664.7 0.0 1.0 1 0 0 1 1 1 1 56kDa selenium binding protein (SBP56) Lactonase PF10282.9 AAL64395.1 - 0.013 14.8 0.0 0.23 10.7 0.0 2.5 2 1 1 3 3 3 0 Lactonase, 7-bladed beta-propeller Topo_Zn_Ribbon PF08272.11 AAL64395.1 - 0.026 14.2 0.1 0.054 13.2 0.1 1.6 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like Rad54_N PF08658.10 AAL64395.1 - 0.26 11.4 0.1 0.4 10.8 0.1 1.2 1 0 0 1 1 1 0 Rad54 N terminal AhpC-TSA PF00578.21 AAL64397.1 - 1.3e-37 128.5 0.0 1.5e-37 128.3 0.0 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AAL64397.1 - 3e-22 78.9 0.0 3.4e-22 78.7 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 AAL64397.1 - 0.047 13.8 0.0 0.28 11.3 0.0 1.9 1 1 1 2 2 2 0 AhpC/TSA antioxidant enzyme SCO1-SenC PF02630.14 AAL64397.1 - 0.19 11.6 0.0 0.29 11.1 0.0 1.2 1 0 0 1 1 1 0 SCO1/SenC Rhodanese PF00581.20 AAL64398.1 - 3.9e-41 139.9 0.1 4e-19 69.1 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain Rieske PF00355.26 AAL64399.1 - 6.4e-12 45.2 0.1 7.5e-12 45.0 0.1 1.1 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 AAL64399.1 - 3.4e-11 43.0 0.0 4e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain DUF4851 PF16143.5 AAL64399.1 - 0.14 11.6 0.1 0.19 11.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4851) POR_N PF01855.19 AAL64401.1 - 3.5e-63 213.5 0.0 4.9e-63 213.0 0.0 1.2 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.18 AAL64401.1 - 1.7e-37 129.2 0.0 3.5e-37 128.2 0.0 1.5 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 AAL64401.1 - 1.4e-06 28.5 0.2 4.6e-06 26.9 0.1 2.0 2 0 0 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_C PF02780.20 AAL64401.1 - 0.0001 22.2 0.0 0.00027 20.8 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_N PF02776.18 AAL64401.1 - 0.00093 18.8 0.1 0.0029 17.2 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Methyltranf_PUA PF13636.6 AAL64401.1 - 0.1 12.6 1.3 0.29 11.1 0.0 2.3 2 0 0 2 2 2 0 RNA-binding PUA-like domain of methyltransferase RsmF ACC_epsilon PF13822.6 AAL64401.1 - 0.18 12.5 0.9 0.46 11.2 0.9 1.7 1 0 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit TPP_enzyme_C PF02775.21 AAL64402.1 - 2e-30 105.6 0.1 3.1e-30 105.0 0.1 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PFO_beta_C PF12367.8 AAL64402.1 - 9.8e-20 70.5 0.3 1.9e-19 69.6 0.3 1.4 1 0 0 1 1 1 1 Pyruvate ferredoxin oxidoreductase beta subunit C terminal BLOC1_2 PF10046.9 AAL64403.1 - 2e-07 31.2 0.1 0.0015 18.8 0.0 2.2 1 1 2 3 3 3 3 Biogenesis of lysosome-related organelles complex-1 subunit 2 PspA_IM30 PF04012.12 AAL64403.1 - 9e-07 28.7 0.0 0.0022 17.6 0.1 2.1 1 1 1 2 2 2 2 PspA/IM30 family DUF1664 PF07889.12 AAL64403.1 - 2.3e-06 27.6 0.1 0.00028 20.9 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) DUF2730 PF10805.8 AAL64403.1 - 3.4e-06 27.1 1.8 0.00057 19.9 0.2 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF2730) FlaC_arch PF05377.11 AAL64403.1 - 8.5e-06 26.1 2.1 0.011 16.2 1.6 3.1 1 1 2 3 3 3 2 Flagella accessory protein C (FlaC) TMF_TATA_bd PF12325.8 AAL64403.1 - 6.5e-05 23.1 0.6 9.8e-05 22.6 0.6 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding CLZ PF16526.5 AAL64403.1 - 7.4e-05 23.0 1.2 0.0043 17.4 1.2 2.6 1 1 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Apolipoprotein PF01442.18 AAL64403.1 - 8e-05 22.6 0.3 0.00011 22.1 0.3 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 AAL64403.1 - 9e-05 22.5 0.0 0.004 17.2 0.0 2.0 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus HSBP1 PF06825.12 AAL64403.1 - 0.00014 21.6 1.8 0.52 10.2 0.1 4.0 1 1 2 3 3 3 1 Heat shock factor binding protein 1 DUF948 PF06103.11 AAL64403.1 - 0.00019 21.6 0.1 0.0012 19.1 0.1 2.1 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF948) bZIP_1 PF00170.21 AAL64403.1 - 0.00021 21.3 1.8 0.018 15.1 0.4 2.8 1 1 2 3 3 3 1 bZIP transcription factor SlyX PF04102.12 AAL64403.1 - 0.00022 21.7 0.2 0.17 12.5 0.0 2.3 1 1 0 2 2 2 1 SlyX Laminin_II PF06009.12 AAL64403.1 - 0.00024 21.1 0.1 0.00054 20.0 0.1 1.5 1 1 0 1 1 1 1 Laminin Domain II Spc7 PF08317.11 AAL64403.1 - 0.00025 20.0 0.0 0.00032 19.7 0.0 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF3450 PF11932.8 AAL64403.1 - 0.00029 20.2 0.0 0.00032 20.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) TMF_DNA_bd PF12329.8 AAL64403.1 - 0.00078 19.4 0.6 0.0017 18.3 0.6 1.6 1 1 0 1 1 1 1 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.9 AAL64403.1 - 0.0009 19.3 0.4 0.0012 18.8 0.4 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 AAL64403.1 - 0.0014 18.9 0.4 0.0017 18.6 0.4 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) TolA_bind_tri PF16331.5 AAL64403.1 - 0.0014 18.6 2.2 0.046 13.8 1.1 3.0 1 1 1 2 2 2 1 TolA binding protein trimerisation PspB PF06667.12 AAL64403.1 - 0.0017 18.4 0.2 0.053 13.6 0.1 2.5 1 1 1 2 2 2 1 Phage shock protein B Myosin_tail_1 PF01576.19 AAL64403.1 - 0.0025 15.7 0.2 0.0029 15.5 0.2 1.0 1 0 0 1 1 1 1 Myosin tail DUF4988 PF16378.5 AAL64403.1 - 0.0028 17.4 0.7 0.055 13.1 0.2 2.3 1 1 0 2 2 2 1 Domain of unknown function ADIP PF11559.8 AAL64403.1 - 0.0028 17.7 0.0 0.0069 16.5 0.0 1.6 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding TACC_C PF05010.14 AAL64403.1 - 0.0031 17.3 0.0 0.0042 16.9 0.0 1.2 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Prefoldin_2 PF01920.20 AAL64403.1 - 0.0035 17.3 0.0 0.035 14.1 0.1 2.2 1 1 0 2 2 2 1 Prefoldin subunit DUF4618 PF15397.6 AAL64403.1 - 0.0037 16.7 0.1 0.02 14.3 0.0 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4618) ABC_tran_CTD PF16326.5 AAL64403.1 - 0.0038 17.5 0.0 0.0083 16.4 0.0 1.6 2 0 0 2 2 1 1 ABC transporter C-terminal domain DUF4164 PF13747.6 AAL64403.1 - 0.0043 17.3 3.5 0.0065 16.7 1.0 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4164) HemX PF04375.14 AAL64403.1 - 0.0044 16.3 0.0 0.005 16.2 0.0 1.1 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase DASH_Dam1 PF08653.10 AAL64403.1 - 0.0048 16.7 0.1 1.6 8.6 0.2 2.4 1 1 1 2 2 2 1 DASH complex subunit Dam1 DUF16 PF01519.16 AAL64403.1 - 0.005 17.3 0.1 0.019 15.5 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function DUF16 Fib_alpha PF08702.10 AAL64403.1 - 0.0052 17.0 0.1 0.017 15.3 0.1 1.7 1 1 0 1 1 1 1 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 AAL64403.1 - 0.0058 17.1 0.0 0.74 10.3 0.1 2.4 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein EzrA PF06160.12 AAL64403.1 - 0.0058 14.9 0.0 0.0073 14.5 0.0 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA HalX PF08663.10 AAL64403.1 - 0.0074 16.6 1.6 7.6 6.9 0.1 3.4 1 1 2 3 3 3 0 HalX domain Atg14 PF10186.9 AAL64403.1 - 0.011 14.8 0.0 0.014 14.5 0.0 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ZapB PF06005.12 AAL64403.1 - 0.011 16.1 0.1 0.02 15.4 0.1 1.5 1 0 0 1 1 1 0 Cell division protein ZapB JIP_LZII PF16471.5 AAL64403.1 - 0.011 15.9 2.4 0.023 14.9 0.9 2.1 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II XhlA PF10779.9 AAL64403.1 - 0.012 15.8 2.1 0.05 13.8 1.1 2.4 1 1 0 2 2 1 0 Haemolysin XhlA DUF4349 PF14257.6 AAL64403.1 - 0.013 15.0 0.6 0.013 15.0 0.6 1.6 1 1 1 2 2 1 0 Domain of unknown function (DUF4349) Flagellin_C PF00700.21 AAL64403.1 - 0.013 15.8 0.1 0.049 14.0 0.1 2.0 1 1 0 1 1 1 0 Bacterial flagellin C-terminal helical region Spectrin PF00435.21 AAL64403.1 - 0.014 15.8 0.0 0.021 15.3 0.0 1.3 1 0 0 1 1 1 0 Spectrin repeat Snapin_Pallidin PF14712.6 AAL64403.1 - 0.014 15.7 0.6 1.9 8.9 0.4 2.5 1 1 1 2 2 2 0 Snapin/Pallidin Fzo_mitofusin PF04799.13 AAL64403.1 - 0.019 14.5 0.1 0.32 10.5 0.1 2.2 1 1 1 2 2 2 0 fzo-like conserved region STAT_alpha PF01017.20 AAL64403.1 - 0.019 14.9 0.0 0.025 14.5 0.0 1.2 1 0 0 1 1 1 0 STAT protein, all-alpha domain DUF4795 PF16043.5 AAL64403.1 - 0.02 14.5 0.1 0.06 12.9 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Prominin PF05478.11 AAL64403.1 - 0.021 12.8 0.1 0.025 12.6 0.1 1.1 1 0 0 1 1 1 0 Prominin GrpE PF01025.19 AAL64403.1 - 0.023 14.4 0.2 0.32 10.6 0.1 1.9 1 1 1 2 2 2 0 GrpE Occludin_ELL PF07303.13 AAL64403.1 - 0.026 15.2 0.0 0.072 13.8 0.0 1.7 1 1 0 1 1 1 0 Occludin homology domain DHR10 PF18595.1 AAL64403.1 - 0.029 14.4 0.3 0.11 12.5 0.2 1.8 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain Hemagglutinin PF00509.18 AAL64403.1 - 0.032 12.6 0.1 0.037 12.5 0.1 1.3 1 0 0 1 1 1 0 Haemagglutinin COG5 PF10392.9 AAL64403.1 - 0.035 14.3 0.1 1.1 9.4 0.1 2.0 1 1 1 2 2 2 0 Golgi transport complex subunit 5 PTRF_SDPR PF15237.6 AAL64403.1 - 0.036 13.7 0.2 0.05 13.2 0.2 1.2 1 0 0 1 1 1 0 PTRF/SDPR family Nup54 PF13874.6 AAL64403.1 - 0.038 14.1 0.3 0.11 12.6 0.2 1.7 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DUF5082 PF16888.5 AAL64403.1 - 0.041 14.2 0.1 1.6 9.0 0.1 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF5082) MbeD_MobD PF04899.12 AAL64403.1 - 0.041 14.0 0.1 3.5 7.8 0.0 2.4 1 1 1 2 2 2 0 MbeD/MobD like DivIC PF04977.15 AAL64403.1 - 0.041 13.6 0.3 1.1 9.1 0.2 2.4 1 1 1 2 2 2 0 Septum formation initiator IFT57 PF10498.9 AAL64403.1 - 0.044 12.7 0.0 0.054 12.5 0.0 1.0 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 FapA PF03961.13 AAL64403.1 - 0.051 12.2 0.0 0.061 11.9 0.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A APG17 PF04108.12 AAL64403.1 - 0.059 12.5 0.0 0.081 12.0 0.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg17 CALCOCO1 PF07888.11 AAL64403.1 - 0.06 12.2 0.2 0.076 11.9 0.2 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Exonuc_VII_L PF02601.15 AAL64403.1 - 0.06 12.9 0.0 0.069 12.7 0.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Fez1 PF06818.15 AAL64403.1 - 0.061 13.8 0.0 0.075 13.5 0.0 1.1 1 0 0 1 1 1 0 Fez1 Matrilin_ccoil PF10393.9 AAL64403.1 - 0.064 13.1 0.2 0.89 9.5 0.0 2.5 2 1 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF2353 PF09789.9 AAL64403.1 - 0.065 12.6 0.2 0.079 12.3 0.2 1.0 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) COG2 PF06148.11 AAL64403.1 - 0.073 13.2 0.6 1.4 9.0 0.6 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Tropomyosin PF00261.20 AAL64403.1 - 0.073 12.4 1.1 0.12 11.7 1.1 1.4 1 1 0 1 1 1 0 Tropomyosin HOOK PF05622.12 AAL64403.1 - 0.079 11.1 0.2 0.086 11.0 0.2 1.1 1 0 0 1 1 1 0 HOOK protein HrpB7 PF09486.10 AAL64403.1 - 0.08 13.3 0.4 0.67 10.3 0.1 1.9 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Lebercilin PF15619.6 AAL64403.1 - 0.08 12.6 0.4 0.21 11.2 0.4 1.7 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF745 PF05335.13 AAL64403.1 - 0.085 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) TelA PF05816.11 AAL64403.1 - 0.088 11.9 0.0 0.13 11.3 0.0 1.4 1 1 0 1 1 1 0 Toxic anion resistance protein (TelA) Cortex-I_coil PF09304.10 AAL64403.1 - 0.089 13.0 1.4 0.13 12.5 1.4 1.3 1 0 0 1 1 1 0 Cortexillin I, coiled coil CdvA PF18822.1 AAL64403.1 - 0.091 12.6 0.4 2.1 8.2 0.4 2.3 1 1 1 2 2 2 0 CdvA-like coiled-coil domain RmuC PF02646.16 AAL64403.1 - 0.093 11.8 0.1 0.19 10.8 0.1 1.6 1 1 0 1 1 1 0 RmuC family Nup88 PF10168.9 AAL64403.1 - 0.096 10.5 0.1 0.11 10.3 0.1 1.1 1 0 0 1 1 1 0 Nuclear pore component DUF4201 PF13870.6 AAL64403.1 - 0.099 12.4 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) TPR_MLP1_2 PF07926.12 AAL64403.1 - 0.1 12.7 0.1 0.34 11.0 0.1 1.7 1 1 1 2 2 1 0 TPR/MLP1/MLP2-like protein DUF3552 PF12072.8 AAL64403.1 - 0.1 12.0 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Tektin PF03148.14 AAL64403.1 - 0.11 11.3 0.0 0.14 10.8 0.0 1.3 1 0 0 1 1 1 0 Tektin family HMMR_N PF15905.5 AAL64403.1 - 0.11 11.9 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Trimer_CC PF08954.11 AAL64403.1 - 0.12 12.0 3.5 1.5 8.4 0.1 3.2 2 1 2 4 4 4 0 Trimerisation motif Vps53_N PF04100.12 AAL64403.1 - 0.12 11.3 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Vps53-like, N-terminal DUF2205 PF10224.9 AAL64403.1 - 0.12 12.3 1.0 5.6 7.0 0.4 3.0 1 1 1 2 2 2 0 Short coiled-coil protein Not3 PF04065.15 AAL64403.1 - 0.12 11.7 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component DASH_Spc19 PF08287.11 AAL64403.1 - 0.13 12.2 0.7 0.57 10.1 0.4 1.9 1 1 1 2 2 2 0 Spc19 FPP PF05911.11 AAL64403.1 - 0.14 10.3 0.0 0.15 10.2 0.0 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil AAA_13 PF13166.6 AAL64403.1 - 0.15 10.7 0.0 0.17 10.5 0.0 1.0 1 0 0 1 1 1 0 AAA domain KxDL PF10241.9 AAL64403.1 - 0.15 12.3 0.3 0.65 10.3 0.2 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein Macoilin PF09726.9 AAL64403.1 - 0.16 10.5 0.2 0.19 10.3 0.2 1.0 1 0 0 1 1 1 0 Macoilin family DegS PF05384.11 AAL64403.1 - 0.16 11.4 1.5 0.22 11.0 0.7 1.7 1 1 0 1 1 1 0 Sensor protein DegS Med9 PF07544.13 AAL64403.1 - 0.18 11.9 0.4 3 8.0 0.1 2.4 1 1 2 3 3 2 0 RNA polymerase II transcription mediator complex subunit 9 WXG100 PF06013.12 AAL64403.1 - 0.19 12.0 0.0 11 6.3 0.0 2.5 1 1 0 2 2 2 0 Proteins of 100 residues with WXG Fmp27_WPPW PF10359.9 AAL64403.1 - 0.22 10.4 0.0 0.23 10.3 0.0 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DrsE PF02635.15 AAL64405.1 - 0.0019 18.5 0.0 0.0025 18.1 0.0 1.2 1 1 0 1 1 1 1 DsrE/DsrF-like family RNR_N PF08343.10 AAL64405.1 - 0.12 12.4 0.0 0.29 11.2 0.0 1.6 2 0 0 2 2 2 0 Ribonucleotide reductase N-terminal Lyase_1 PF00206.20 AAL64406.1 - 1.4e-84 284.2 0.0 1.9e-84 283.7 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 AAL64406.1 - 1.5e-08 34.9 0.1 9.1e-08 32.4 0.1 2.4 2 1 0 2 2 2 1 Fumarase C C-terminus Pyr_redox_2 PF07992.14 AAL64407.1 - 4.5e-44 150.8 0.3 5.5e-44 150.6 0.3 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAL64407.1 - 4.8e-27 95.0 0.1 8.7e-20 71.2 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAL64407.1 - 3.5e-17 62.7 1.3 4.5e-11 43.2 0.0 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AAL64407.1 - 1.1e-10 41.2 5.1 1.5e-05 24.3 1.0 3.5 3 1 0 4 4 4 2 FAD binding domain GIDA PF01134.22 AAL64407.1 - 5.7e-09 35.5 4.5 2.6e-05 23.5 0.6 3.7 4 0 0 4 4 4 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 AAL64407.1 - 6.2e-09 35.7 3.0 1.7e-08 34.3 0.3 2.4 2 1 1 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 AAL64407.1 - 4.5e-06 25.6 5.8 0.0013 17.5 0.7 3.4 4 0 0 4 4 4 2 HI0933-like protein FAD_binding_3 PF01494.19 AAL64407.1 - 5.1e-06 26.0 1.1 0.0007 18.9 0.6 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 AAL64407.1 - 5.7e-05 23.3 0.7 0.0016 18.7 0.2 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 AAL64407.1 - 0.00013 21.3 1.7 0.00032 20.0 0.2 2.3 3 0 0 3 3 3 1 Thi4 family DAO PF01266.24 AAL64407.1 - 0.00021 21.0 3.3 0.0053 16.4 1.8 2.4 1 1 1 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 AAL64407.1 - 0.00043 19.6 1.0 0.11 11.8 0.6 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 AAL64407.1 - 0.0017 18.7 0.1 0.44 11.0 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding Lycopene_cycl PF05834.12 AAL64407.1 - 0.014 14.4 1.4 0.031 13.3 0.4 2.0 2 1 1 3 3 3 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 AAL64407.1 - 0.14 12.2 0.8 20 5.2 0.0 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 AAL64407.1 - 0.23 10.3 4.4 0.58 8.9 0.5 2.3 3 0 0 3 3 3 0 Tryptophan halogenase DUF2654 PF10849.8 AAL64407.1 - 0.25 11.6 1.7 0.63 10.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2654) K_oxygenase PF13434.6 AAL64407.1 - 0.39 9.8 1.0 35 3.4 0.0 2.7 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Leader_Thr PF08254.11 AAL64407.1 - 0.88 9.4 2.3 10 6.0 0.1 2.4 2 0 0 2 2 2 0 Threonine leader peptide YHS PF04945.13 AAL64408.1 - 1.4e-20 73.1 1.3 1.8e-20 72.8 1.3 1.1 1 0 0 1 1 1 1 YHS domain Arc_trans_TRASH PF08394.10 AAL64408.1 - 0.00026 21.3 0.9 0.00038 20.7 0.9 1.3 1 0 0 1 1 1 1 Archaeal TRASH domain zf-FCS PF06467.14 AAL64408.1 - 0.0017 18.2 1.1 0.0024 17.8 0.8 1.5 1 1 0 1 1 1 1 MYM-type Zinc finger with FCS sequence motif FAP206 PF12018.8 AAL64408.1 - 0.07 12.6 0.0 0.074 12.5 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function DUF2116 PF09889.9 AAL64408.1 - 0.16 12.0 0.8 0.36 10.9 0.2 1.8 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) MarR_2 PF12802.7 AAL64410.1 - 0.0076 16.1 0.2 0.012 15.5 0.2 1.3 1 0 0 1 1 1 1 MarR family TrmB PF01978.19 AAL64410.1 - 0.014 15.3 0.4 0.02 14.8 0.4 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Laminin_II PF06009.12 AAL64410.1 - 0.022 14.8 0.1 0.031 14.3 0.1 1.1 1 0 0 1 1 1 0 Laminin Domain II Pilin_N PF07790.11 AAL64410.1 - 0.14 13.1 0.6 17 6.4 0.0 2.3 2 0 0 2 2 2 0 Archaeal Type IV pilin, N-terminal Phage_terminase PF10668.9 AAL64410.1 - 0.14 12.2 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Phage terminase small subunit DUF411 PF04214.13 AAL64411.1 - 3e-14 52.7 0.0 4.7e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF Thioredoxin_2 PF13098.6 AAL64412.1 - 1.5e-05 25.4 0.0 2.8e-05 24.5 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.20 AAL64412.1 - 0.072 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin AC_N PF16214.5 AAL64413.1 - 2 7.4 5.4 2.3 7.3 5.4 1.1 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region DUF2070 PF09843.9 AAL64413.1 - 4.3 5.5 10.8 4.9 5.3 10.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) SAYSvFN PF10260.9 AAL64413.1 - 8.4 6.4 6.4 13 5.8 2.9 2.3 1 1 1 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) PIN PF01850.21 AAL64414.1 - 8e-11 42.5 0.6 1e-10 42.2 0.6 1.1 1 0 0 1 1 1 1 PIN domain CcdA PF07362.12 AAL64415.1 - 6.1e-06 26.6 2.1 6.1e-06 26.6 2.1 1.9 1 1 1 2 2 2 1 Post-segregation antitoxin CcdA DUF4145 PF13643.6 AAL64415.1 - 0.00049 20.2 1.1 0.00058 19.9 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4145) PSK_trans_fac PF07704.11 AAL64415.1 - 0.0027 18.4 10.2 0.0035 18.1 10.2 1.3 1 1 0 1 1 1 1 Rv0623-like transcription factor PRP1_N PF06424.12 AAL64415.1 - 0.0056 17.1 1.3 0.0058 17.0 1.3 1.2 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal DUF4140 PF13600.6 AAL64415.1 - 0.036 14.5 3.3 0.043 14.3 3.3 1.1 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) MazG-like PF12643.7 AAL64415.1 - 0.047 14.0 0.7 0.086 13.1 0.7 1.4 1 1 0 1 1 1 0 MazG-like family Dabb PF07876.12 AAL64415.1 - 0.085 13.5 0.2 0.12 13.0 0.2 1.3 1 0 0 1 1 1 0 Stress responsive A/B Barrel Domain bVLRF1 PF18826.1 AAL64415.1 - 0.098 12.5 0.8 0.11 12.3 0.8 1.3 1 1 0 1 1 1 0 bacteroidetes VLRF1 release factor NEMP PF10225.9 AAL64415.1 - 0.19 11.3 0.5 0.18 11.5 0.5 1.0 1 0 0 1 1 1 0 NEMP family E1-E2_ATPase PF00122.20 AAL64417.1 - 2e-58 196.9 0.5 4.1e-58 195.9 0.5 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 AAL64417.1 - 1.4e-37 130.1 2.0 2.8e-37 129.0 2.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 AAL64417.1 - 1.7e-13 50.8 0.3 6.2e-12 45.8 0.0 3.1 3 0 0 3 3 3 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 AAL64417.1 - 8e-07 29.0 0.4 0.00026 20.8 0.5 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 AAL64417.1 - 1.2e-06 29.0 0.1 3e-06 27.8 0.1 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DAHP_snth_FXD PF18152.1 AAL64417.1 - 0.023 14.5 0.2 0.5 10.2 0.1 2.8 2 0 0 2 2 2 0 DAHP synthase ferredoxin-like domain DUF86 PF01934.17 AAL64418.1 - 1.2e-09 38.0 0.0 1.5e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF86 HTH_12 PF08461.10 AAL64418.1 - 0.051 13.5 0.1 0.083 12.8 0.1 1.3 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain Polbeta PF18765.1 AAL64419.1 - 4.2e-07 29.9 0.0 5.8e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 AAL64419.1 - 0.00039 20.6 0.0 0.00066 19.9 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF996 PF06195.13 AAL64420.1 - 1.1e-27 96.9 10.1 1.5e-27 96.6 10.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF996) COX7a PF02238.15 AAL64420.1 - 4.9 7.6 12.3 2.2 8.8 0.1 3.7 2 2 1 3 3 3 0 Cytochrome c oxidase subunit VII Pox_A9 PF04835.12 AAL64420.1 - 5.6 7.2 5.5 11 6.2 1.6 2.5 2 0 0 2 2 2 0 A9 protein conserved region DUF2070 PF09843.9 AAL64420.1 - 9.6 4.4 9.5 13 4.0 9.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Sugar_tr PF00083.24 AAL64422.1 - 6.5e-29 101.1 26.6 2.4e-21 76.1 3.0 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 AAL64422.1 - 3.8e-28 98.4 49.1 4.9e-18 65.2 20.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 AAL64422.1 - 1.9e-05 23.7 19.5 0.0011 17.9 10.7 3.2 1 1 2 3 3 3 3 MFS_1 like family DUF1646 PF07854.12 AAL64423.1 - 3.1e-142 474.1 29.3 3.6e-142 473.9 29.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1646) Capsid_VP7 PF17071.5 AAL64423.1 - 0.088 12.1 0.2 0.14 11.4 0.2 1.3 1 0 0 1 1 1 0 Outer capsid protein VP7 FGase PF05013.12 AAL64424.1 - 0.12 12.5 0.0 0.12 12.5 0.0 1.0 1 0 0 1 1 1 0 N-formylglutamate amidohydrolase Chorismate_bind PF00425.18 AAL64427.1 - 4.5e-06 26.4 0.0 5.9e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 chorismate binding enzyme T2SSE PF00437.20 AAL64428.1 - 9.5e-37 126.5 0.2 1.2e-36 126.2 0.2 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 AAL64428.1 - 9.7e-07 29.4 0.0 1.5e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 AAL64428.1 - 2.1e-05 25.1 0.0 4.2e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAL64428.1 - 0.00019 21.1 0.0 0.00065 19.4 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AAL64428.1 - 0.00019 21.7 0.0 0.00066 20.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 AAL64428.1 - 0.00047 20.1 0.0 0.00085 19.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 AAL64428.1 - 0.00078 19.4 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase cobW PF02492.19 AAL64428.1 - 0.00079 19.1 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 AAL64428.1 - 0.00089 19.3 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 AAL64428.1 - 0.001 19.3 0.0 0.002 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAL64428.1 - 0.0018 18.7 0.1 0.0035 17.7 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.27 AAL64428.1 - 0.0032 17.0 0.0 0.0058 16.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 AAL64428.1 - 0.0041 16.7 0.0 0.0067 16.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 AAL64428.1 - 0.0071 15.7 0.4 0.015 14.7 0.0 1.7 2 0 0 2 2 1 1 FtsK/SpoIIIE family IstB_IS21 PF01695.17 AAL64428.1 - 0.012 15.3 0.0 0.029 14.1 0.0 1.6 2 0 0 2 2 1 0 IstB-like ATP binding protein Dynamin_N PF00350.23 AAL64428.1 - 0.013 15.6 0.0 0.057 13.5 0.0 1.9 2 0 0 2 2 2 0 Dynamin family Guanylate_kin PF00625.21 AAL64428.1 - 0.014 15.1 0.0 0.03 14.0 0.0 1.6 1 0 0 1 1 1 0 Guanylate kinase AAA_18 PF13238.6 AAL64428.1 - 0.02 15.4 0.1 0.037 14.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 AAL64428.1 - 0.026 13.5 0.0 0.042 12.8 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 AAL64428.1 - 0.026 14.3 0.0 0.067 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AAL64428.1 - 0.032 14.0 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 AAL64428.1 - 0.033 13.5 0.0 0.048 12.9 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_33 PF13671.6 AAL64428.1 - 0.033 14.3 0.1 0.14 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 AAL64428.1 - 0.035 13.9 0.0 0.084 12.6 0.0 1.7 2 0 0 2 2 2 0 DEAD/DEAH box helicase SMC_N PF02463.19 AAL64428.1 - 0.037 13.5 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain NACHT PF05729.12 AAL64428.1 - 0.04 13.8 0.0 0.098 12.6 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Mg_chelatase PF01078.21 AAL64428.1 - 0.05 13.0 0.0 0.078 12.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Roc PF08477.13 AAL64428.1 - 0.057 13.6 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 AAL64428.1 - 0.058 13.4 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ResIII PF04851.15 AAL64428.1 - 0.075 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TsaE PF02367.17 AAL64428.1 - 0.081 12.9 0.1 0.19 11.7 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 AAL64428.1 - 0.082 12.5 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_14 PF13173.6 AAL64428.1 - 0.086 12.9 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 AAL64428.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 AAL64428.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_10 PF12846.7 AAL64428.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain MobB PF03205.14 AAL64428.1 - 0.16 11.8 0.1 0.34 10.8 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATPase_2 PF01637.18 AAL64428.1 - 0.17 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_15 PF13175.6 AAL64428.1 - 0.25 11.0 0.0 0.35 10.5 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain T2SSF PF00482.23 AAL64429.1 - 4e-17 62.3 7.1 4e-17 62.3 7.1 2.0 2 0 0 2 2 2 1 Type II secretion system (T2SS), protein F NitrOD5 PF11537.8 AAL64430.1 - 0.0033 17.5 0.2 0.0038 17.3 0.2 1.2 1 0 0 1 1 1 1 Nitrosopumilus output domain 5 HEPN PF05168.14 AAL64432.1 - 1.5e-32 112.2 0.1 1.7e-32 112.0 0.1 1.0 1 0 0 1 1 1 1 HEPN domain PaREP1 PF05942.11 AAL64432.1 - 0.076 12.9 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Archaeal PaREP1/PaREP8 family NTP_transf_2 PF01909.23 AAL64433.1 - 1.8e-09 37.7 0.0 2e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 AAL64433.1 - 5e-05 23.3 0.0 7.5e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase ABC_tran PF00005.27 AAL64434.1 - 4.1e-32 111.6 0.0 5.1e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAL64434.1 - 2.3e-07 30.9 0.0 0.012 15.5 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AAL64434.1 - 0.0004 20.1 0.0 0.00076 19.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 AAL64434.1 - 0.00083 18.9 0.0 0.88 9.0 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 AAL64434.1 - 0.02 14.8 0.5 0.061 13.2 0.1 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_25 PF13481.6 AAL64434.1 - 0.025 14.1 0.0 0.28 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 AAL64434.1 - 0.034 14.3 0.0 0.069 13.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AAL64434.1 - 0.047 14.2 0.0 0.085 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AAL64434.1 - 0.052 13.3 0.0 0.094 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 AAL64434.1 - 0.074 13.3 0.1 1.8 8.9 0.1 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 AAL64434.1 - 0.16 12.3 0.2 0.19 12.1 0.2 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 AAL64434.1 - 0.24 11.7 2.0 0.68 10.2 0.5 2.2 2 1 1 3 3 3 0 AAA domain Apolipoprotein PF01442.18 AAL64435.1 - 0.00039 20.4 1.7 0.0014 18.5 0.7 1.9 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain DUF1664 PF07889.12 AAL64435.1 - 0.00057 19.9 1.0 0.0019 18.2 0.8 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF1664) Mst1_SARAH PF11629.8 AAL64435.1 - 0.0096 16.0 3.5 0.072 13.2 0.4 2.8 2 1 0 2 2 2 1 C terminal SARAH domain of Mst1 DUF3450 PF11932.8 AAL64435.1 - 0.013 14.8 0.1 0.018 14.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Seryl_tRNA_N PF02403.22 AAL64435.1 - 0.015 15.5 2.1 0.018 15.3 0.9 1.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF948 PF06103.11 AAL64435.1 - 0.019 15.2 0.3 0.045 14.0 0.1 1.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) TMF_DNA_bd PF12329.8 AAL64435.1 - 0.025 14.5 3.0 0.025 14.5 3.0 1.9 2 1 1 3 3 2 0 TATA element modulatory factor 1 DNA binding Nup54 PF13874.6 AAL64435.1 - 0.036 14.2 0.1 0.18 11.9 0.0 1.9 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Vac_Fusion PF02346.16 AAL64435.1 - 0.038 13.6 0.3 0.11 12.1 0.3 1.9 1 1 0 1 1 1 0 Chordopoxvirus multifunctional envelope protein A27 PEARLI-4 PF05278.12 AAL64435.1 - 0.055 13.1 1.9 0.096 12.3 1.9 1.4 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Laminin_II PF06009.12 AAL64435.1 - 0.061 13.3 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Laminin Domain II IlvC PF01450.19 AAL64435.1 - 0.073 13.4 0.4 0.33 11.2 0.0 1.9 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain Syntaxin-6_N PF09177.11 AAL64435.1 - 0.073 13.6 1.5 1.1 9.8 0.3 2.5 1 1 0 2 2 2 0 Syntaxin 6, N-terminal Vip3A_N PF12495.8 AAL64435.1 - 0.11 12.4 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal Baculo_PEP_C PF04513.12 AAL64435.1 - 0.11 12.5 0.0 0.61 10.1 0.0 1.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SGIII PF15467.6 AAL64435.1 - 0.22 10.7 1.5 0.3 10.3 0.3 1.6 2 0 0 2 2 2 0 Secretogranin-3 TPR_MLP1_2 PF07926.12 AAL64435.1 - 0.53 10.3 6.0 0.25 11.4 3.6 1.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF883 PF05957.13 AAL64435.1 - 0.79 10.4 7.2 2.6 8.7 1.8 2.9 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF883) CdvA PF18822.1 AAL64435.1 - 1.1 9.1 6.9 1.3 8.8 3.6 2.5 1 1 0 1 1 1 0 CdvA-like coiled-coil domain Prefoldin_2 PF01920.20 AAL64435.1 - 1.4 8.9 6.3 0.81 9.7 3.0 2.2 2 1 0 2 2 2 0 Prefoldin subunit Ras PF00071.22 AAL64437.1 - 4.4e-08 32.9 1.1 9e-05 22.1 0.0 2.1 2 0 0 2 2 2 2 Ras family Arf PF00025.21 AAL64437.1 - 6.5e-05 22.4 0.0 0.00023 20.7 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 AAL64437.1 - 0.00029 20.9 0.0 0.00037 20.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 AAL64437.1 - 0.011 15.9 0.1 0.2 11.9 0.0 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 AAL64437.1 - 0.012 15.4 0.1 0.022 14.5 0.1 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SmpA_OmlA PF04355.13 AAL64437.1 - 0.051 13.4 0.0 0.079 12.8 0.0 1.2 1 0 0 1 1 1 0 SmpA / OmlA family RsgA_GTPase PF03193.16 AAL64437.1 - 0.055 13.4 0.1 0.21 11.5 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase SRP54 PF00448.22 AAL64437.1 - 0.06 13.0 0.1 0.1 12.2 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 AAL64437.1 - 0.076 13.4 0.0 0.08 13.3 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_3 PF07726.11 AAL64437.1 - 0.14 12.1 0.0 19 5.2 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 AAL64437.1 - 0.16 12.0 0.4 0.25 11.4 0.4 1.5 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 AAL64437.1 - 0.19 11.6 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 AAL64437.1 - 0.19 11.3 0.0 0.33 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 AAL64437.1 - 0.2 11.6 0.1 0.33 11.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.17 AAL64437.1 - 0.21 11.4 0.0 13 5.5 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 AAL64437.1 - 0.21 12.1 0.1 0.22 12.0 0.1 1.4 1 1 0 1 1 1 0 ABC transporter DHH PF01368.20 AAL64439.1 - 7.9e-07 29.3 0.0 2.2e-06 27.8 0.0 1.6 2 0 0 2 2 2 1 DHH family DHHA1 PF02272.19 AAL64440.1 - 2.9e-13 50.4 0.1 3.3e-13 50.2 0.1 1.1 1 0 0 1 1 1 1 DHHA1 domain Peptidase_S49 PF01343.18 AAL64441.1 - 6.2e-18 65.2 3.5 2.2e-16 60.2 3.5 2.3 1 1 0 1 1 1 1 Peptidase family S49 CLP_protease PF00574.23 AAL64441.1 - 1.8e-12 47.5 0.4 8.7e-10 38.8 0.3 2.2 2 0 0 2 2 2 2 Clp protease DUF881 PF05949.12 AAL64441.1 - 0.0053 16.6 0.1 0.81 9.6 0.1 3.0 3 0 0 3 3 3 1 Bacterial protein of unknown function (DUF881) Trypsin_2 PF13365.6 AAL64442.1 - 3.1e-24 86.6 0.8 4.4e-24 86.1 0.8 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 AAL64442.1 - 4.3e-10 39.8 0.0 9.5e-10 38.7 0.0 1.5 1 1 0 1 1 1 1 Trypsin PDZ_6 PF17820.1 AAL64442.1 - 6.8e-10 38.6 0.1 3.3e-09 36.4 0.1 2.1 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 AAL64442.1 - 7.6e-10 39.0 0.0 2.1e-09 37.6 0.0 1.7 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 AAL64442.1 - 9.4e-08 32.3 0.0 3.1e-07 30.6 0.0 1.9 2 0 0 2 2 2 1 PDZ domain Peptidase_S29 PF02907.15 AAL64442.1 - 0.035 13.9 0.1 0.092 12.5 0.0 1.6 2 0 0 2 2 2 0 Hepatitis C virus NS3 protease Peptidase_S46 PF10459.9 AAL64442.1 - 0.052 12.2 0.2 0.073 11.7 0.2 1.1 1 0 0 1 1 1 0 Peptidase S46 Tricorn_PDZ PF14685.6 AAL64442.1 - 0.13 12.2 0.0 0.37 10.8 0.0 1.8 1 0 0 1 1 1 0 Tricorn protease PDZ domain Cupin_2 PF07883.11 AAL64443.1 - 1.8e-14 53.2 0.2 2.4e-14 52.8 0.2 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 AAL64443.1 - 1.1e-08 35.0 0.0 1.5e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 AraC-like ligand binding domain PCO_ADO PF07847.12 AAL64443.1 - 4.7e-05 22.9 0.0 0.059 12.8 0.0 2.0 1 1 0 2 2 2 2 PCO_ADO EutQ PF06249.12 AAL64443.1 - 0.00066 19.5 0.0 0.0008 19.2 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_1 PF00190.22 AAL64443.1 - 0.0013 18.4 0.2 0.0033 17.0 0.2 1.5 1 1 0 1 1 1 1 Cupin DMSP_lyase PF16867.5 AAL64443.1 - 0.0047 16.6 0.0 0.0053 16.4 0.0 1.1 1 0 0 1 1 1 1 Dimethlysulfonioproprionate lyase Cupin_3 PF05899.12 AAL64443.1 - 0.0068 16.1 0.0 0.0094 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) ARD PF03079.14 AAL64443.1 - 0.011 15.9 0.1 0.014 15.6 0.1 1.2 1 0 0 1 1 1 0 ARD/ARD' family DUF4863 PF16155.5 AAL64443.1 - 0.034 14.0 0.0 0.04 13.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4863) KduI PF04962.12 AAL64443.1 - 0.046 13.0 0.0 0.062 12.6 0.0 1.2 1 0 0 1 1 1 0 KduI/IolB family MannoseP_isomer PF01050.18 AAL64443.1 - 0.078 12.9 0.0 0.093 12.6 0.0 1.1 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase Cupin_7 PF12973.7 AAL64443.1 - 0.086 12.8 0.0 0.12 12.3 0.0 1.4 1 1 0 1 1 1 0 ChrR Cupin-like domain HTH_42 PF06224.12 AAL64444.1 - 0.00016 21.3 0.1 0.00017 21.2 0.1 1.0 1 0 0 1 1 1 1 Winged helix DNA-binding domain Peptidase_M20 PF01546.28 AAL64445.1 - 9.8e-28 97.3 0.0 3.5e-27 95.5 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AAL64445.1 - 9.3e-09 35.2 0.0 1.6e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 AAL64445.1 - 0.0003 20.5 0.0 0.00041 20.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 ATPase PF06745.13 AAL64446.1 - 2.3e-13 50.1 0.2 3.3e-08 33.2 0.1 3.4 2 1 0 2 2 2 2 KaiC RecA PF00154.21 AAL64446.1 - 2.4e-05 24.0 0.0 0.11 11.9 0.0 2.3 2 0 0 2 2 2 2 recA bacterial DNA recombination protein AAA_16 PF13191.6 AAL64446.1 - 0.00087 19.7 0.0 0.0016 18.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AAL64446.1 - 0.0089 16.3 0.0 0.036 14.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 AAL64446.1 - 0.0096 15.9 0.1 0.16 11.9 0.1 2.5 2 1 0 2 2 2 1 NACHT domain DUF2075 PF09848.9 AAL64446.1 - 0.012 14.9 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.6 AAL64446.1 - 0.014 15.8 0.0 0.024 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AAL64446.1 - 0.039 14.1 0.0 0.068 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 AAL64446.1 - 0.04 14.2 0.0 0.25 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain GvpD PF07088.11 AAL64446.1 - 0.049 12.3 0.3 5.5 5.5 0.1 2.4 2 1 0 2 2 2 0 GvpD gas vesicle protein AAA PF00004.29 AAL64446.1 - 0.1 13.0 0.0 0.2 12.1 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 AAL64446.1 - 0.14 11.4 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Rad51 PF08423.11 AAL64446.1 - 0.21 10.8 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 Rad51 AAA_25 PF13481.6 AAL64446.1 - 0.29 10.7 4.6 5.3 6.6 0.5 3.4 2 2 0 2 2 2 0 AAA domain DUF3665 PF12427.8 AAL64447.1 - 0.23 11.2 0.4 0.36 10.6 0.4 1.3 1 0 0 1 1 1 0 Branched-chain amino acid aminotransferase Methyltransf_11 PF08241.12 AAL64450.1 - 4.7e-06 27.2 0.0 8e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAL64450.1 - 0.032 14.9 0.0 0.06 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain NTPase_I-T PF01931.18 AAL64451.1 - 1.1e-43 148.8 0.0 1.2e-43 148.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF84 Baculo_PEP_C PF04513.12 AAL64453.1 - 0.0074 16.3 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus PaREP1 PF05942.11 AAL64454.1 - 9.7e-26 90.0 1.8 1.3e-25 89.6 1.8 1.2 1 0 0 1 1 1 1 Archaeal PaREP1/PaREP8 family Sec16_C PF12931.7 AAL64454.1 - 0.086 12.5 0.0 0.098 12.3 0.0 1.1 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 PaREP1 PF05942.11 AAL64456.1 - 7.6e-32 109.6 0.5 7.6e-32 109.6 0.5 1.6 2 0 0 2 2 2 1 Archaeal PaREP1/PaREP8 family SOR_SNZ PF01680.17 AAL64457.1 - 2.4e-94 314.9 2.8 3.1e-94 314.6 2.8 1.1 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 AAL64457.1 - 1.8e-06 27.4 1.8 3e-06 26.7 0.1 2.0 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG Dus PF01207.17 AAL64457.1 - 0.00019 20.6 3.4 0.068 12.2 0.0 3.3 2 2 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 AAL64457.1 - 0.0013 18.3 0.4 0.45 9.9 0.1 3.1 2 1 0 2 2 2 1 Histidine biosynthesis protein NMO PF03060.15 AAL64457.1 - 0.0023 17.4 0.1 0.0023 17.4 0.1 1.7 2 0 0 2 2 2 1 Nitronate monooxygenase IGPS PF00218.21 AAL64457.1 - 0.0072 15.5 0.0 0.11 11.7 0.0 2.2 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase NanE PF04131.14 AAL64457.1 - 0.014 14.6 0.6 0.065 12.4 0.0 2.4 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase TetR_C_27 PF17935.1 AAL64457.1 - 0.032 14.3 0.0 0.07 13.2 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain OMPdecase PF00215.24 AAL64457.1 - 0.035 13.7 0.0 0.2 11.2 0.1 2.1 1 1 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Glu_synthase PF01645.17 AAL64457.1 - 0.083 12.0 0.1 0.18 10.9 0.1 1.5 1 0 0 1 1 1 0 Conserved region in glutamate synthase PA PF02225.22 AAL64457.1 - 0.14 12.2 0.5 0.31 11.1 0.2 1.7 2 0 0 2 2 2 0 PA domain SNO PF01174.19 AAL64458.1 - 5.9e-49 166.5 0.1 7.2e-49 166.2 0.1 1.0 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 AAL64458.1 - 2.6e-08 33.7 0.0 4.2e-08 33.0 0.0 1.3 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 AAL64458.1 - 5e-08 32.9 0.1 2.5e-07 30.7 0.1 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_S51 PF03575.17 AAL64458.1 - 7.3e-08 32.3 0.1 1.1e-07 31.8 0.1 1.2 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.24 AAL64458.1 - 0.0016 18.3 0.4 0.0029 17.4 0.4 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_5 PF13507.6 AAL64458.1 - 0.089 11.9 0.0 0.17 10.9 0.0 1.7 1 1 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain PaREP1 PF05942.11 AAL64459.1 - 2.3e-27 95.2 3.1 2.9e-27 94.9 3.1 1.1 1 0 0 1 1 1 1 Archaeal PaREP1/PaREP8 family HEPN PF05168.14 AAL64459.1 - 0.00036 20.6 7.1 0.048 13.8 7.1 2.2 1 1 0 1 1 1 1 HEPN domain DUF973 PF06157.11 AAL64460.1 - 8.5e-13 48.0 27.4 1e-12 47.7 27.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF973) TctB PF07331.11 AAL64462.1 - 0.00025 21.3 4.0 0.00025 21.3 4.0 2.1 1 1 1 2 2 2 1 Tripartite tricarboxylate transporter TctB family Phage_holin_4_2 PF04020.13 AAL64462.1 - 0.0013 19.4 13.3 0.0047 17.6 12.5 1.8 1 1 0 1 1 1 1 Mycobacterial 4 TMS phage holin, superfamily IV Gly-zipper_Omp PF13488.6 AAL64462.1 - 0.0065 16.5 0.2 0.0065 16.5 0.2 1.8 2 1 0 2 2 2 1 Glycine zipper Yip1 PF04893.17 AAL64462.1 - 0.13 12.0 21.0 0.24 11.1 21.0 1.5 1 1 0 1 1 1 0 Yip1 domain Phage_holin_2_4 PF16082.5 AAL64462.1 - 0.21 11.3 0.1 0.21 11.3 0.1 2.3 3 0 0 3 3 3 0 Bacteriophage holin family, superfamily II-like UcrQ PF02939.16 AAL64463.1 - 0.15 12.0 0.0 0.19 11.7 0.0 1.1 1 0 0 1 1 1 0 UcrQ family Fer4 PF00037.27 AAL64464.1 - 9.8e-22 75.8 48.3 3.7e-07 29.7 2.8 5.5 6 0 0 6 6 5 4 4Fe-4S binding domain Fer4_7 PF12838.7 AAL64464.1 - 1.7e-18 66.9 37.3 6.3e-10 39.5 10.4 3.9 3 2 1 4 4 4 4 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAL64464.1 - 2.4e-16 60.4 27.2 0.0019 19.1 5.4 4.7 4 1 0 4 4 4 4 4Fe-4S double cluster binding domain Fer4_6 PF12837.7 AAL64464.1 - 4e-16 58.3 43.9 5.8e-05 23.0 2.6 5.5 5 0 0 5 5 5 4 4Fe-4S binding domain Fer4_10 PF13237.6 AAL64464.1 - 3.8e-15 55.7 35.7 1.3e-09 38.0 6.6 4.3 4 1 1 5 5 4 3 4Fe-4S dicluster domain Fer4_21 PF14697.6 AAL64464.1 - 1.1e-14 54.2 36.3 8.7e-12 45.0 10.7 3.9 3 1 2 5 5 5 4 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAL64464.1 - 2.4e-14 53.2 35.1 7.7e-06 26.0 9.9 4.2 4 2 1 5 5 4 4 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAL64464.1 - 2.8e-13 49.1 41.9 0.00077 19.4 2.3 6.0 6 0 0 6 6 6 4 4Fe-4S binding domain Fer4_8 PF13183.6 AAL64464.1 - 2.9e-11 43.6 31.9 0.002 18.5 0.5 4.6 3 2 1 4 4 4 4 4Fe-4S dicluster domain Fer4_4 PF12800.7 AAL64464.1 - 7.8e-10 38.5 37.6 0.012 16.0 3.4 5.4 5 0 0 5 5 5 4 4Fe-4S binding domain Fer4_17 PF13534.6 AAL64464.1 - 1.6e-06 28.5 38.5 0.016 15.7 0.6 5.3 4 3 2 6 6 6 4 4Fe-4S dicluster domain Fer4_15 PF13459.6 AAL64464.1 - 7.2e-05 23.4 25.5 0.02 15.6 1.3 5.0 4 1 0 4 4 4 3 4Fe-4S single cluster domain Fer4_13 PF13370.6 AAL64464.1 - 0.00023 21.6 37.5 0.32 11.6 2.6 4.9 5 0 0 5 5 4 4 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 AAL64464.1 - 0.00024 21.3 28.4 0.015 15.5 8.9 3.8 2 2 1 3 3 3 3 4Fe-4S dicluster domain Fer4_3 PF12798.7 AAL64464.1 - 0.0028 18.5 18.0 0.0047 17.8 6.0 5.2 6 0 0 6 6 4 2 4Fe-4S binding domain ETF_QO PF05187.13 AAL64464.1 - 0.023 14.9 1.3 0.023 14.9 1.3 2.5 2 0 0 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 AAL64464.1 - 0.041 14.7 28.5 2.5 9.0 0.5 4.7 3 2 2 5 5 5 0 4Fe-4S dicluster domain zf-trcl PF13451.6 AAL64464.1 - 0.11 12.4 0.2 0.11 12.4 0.2 3.3 4 1 0 4 4 4 0 Probable zinc-ribbon domain UCR_Fe-S_N PF10399.9 AAL64464.1 - 0.69 9.3 2.0 1.9 7.9 0.0 2.4 3 0 0 3 3 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal CoA_trans PF01144.23 AAL64465.1 - 4e-40 137.5 0.4 2.3e-35 122.0 0.0 2.9 2 1 0 2 2 2 2 Coenzyme A transferase Mal_decarbox_Al PF16957.5 AAL64465.1 - 1.6e-05 23.5 0.1 2.9e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 Malonate decarboxylase, alpha subunit, transporter DUF4310 PF14187.6 AAL64465.1 - 0.026 14.2 0.1 0.048 13.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4310) MazE_antitoxin PF04014.18 AAL64466.1 - 5.4e-15 54.9 0.8 9.1e-15 54.2 0.8 1.4 1 0 0 1 1 1 1 Antidote-toxin recognition MazE, bacterial antitoxin PrlF_antitoxin PF15937.5 AAL64466.1 - 0.00033 21.1 0.2 0.00059 20.2 0.1 1.4 1 1 0 1 1 1 1 prlF antitoxin for toxin YhaV_toxin eIF-1a PF01176.19 AAL64466.1 - 0.0065 16.2 1.3 0.29 11.0 0.3 2.1 1 1 1 2 2 2 2 Translation initiation factor 1A / IF-1 DUF1905 PF08922.11 AAL64466.1 - 0.018 15.1 0.2 0.085 12.9 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1905) AbrB-like PF14250.6 AAL64466.1 - 0.021 14.9 0.0 0.029 14.5 0.0 1.3 1 0 0 1 1 1 0 AbrB-like transcriptional regulator SH3_2 PF07653.17 AAL64466.1 - 0.08 12.6 0.1 0.28 10.9 0.1 1.9 1 1 0 1 1 1 0 Variant SH3 domain PIN PF01850.21 AAL64467.1 - 1.6e-14 54.5 1.7 1.8e-14 54.3 1.7 1.0 1 0 0 1 1 1 1 PIN domain PIN_9 PF18477.1 AAL64467.1 - 4.4e-05 23.8 0.4 0.0016 18.7 0.4 2.3 1 1 0 1 1 1 1 PIN like domain PIN_4 PF13638.6 AAL64467.1 - 0.0025 18.1 0.3 0.0048 17.2 0.3 1.5 1 1 0 1 1 1 1 PIN domain PIN_2 PF10130.9 AAL64467.1 - 0.011 15.9 0.1 0.015 15.5 0.1 1.1 1 0 0 1 1 1 0 PIN domain Mut7-C PF01927.16 AAL64467.1 - 0.16 12.1 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Mut7-C RNAse domain PaREP1 PF05942.11 AAL64468.1 - 2.8e-31 107.8 4.7 2.8e-31 107.8 4.7 1.3 2 0 0 2 2 2 1 Archaeal PaREP1/PaREP8 family DUF4398 PF14346.6 AAL64468.1 - 0.62 10.7 10.7 0.53 10.9 9.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4398) adh_short_C2 PF13561.6 AAL64469.1 - 9.4e-55 185.7 3.8 1.2e-54 185.3 3.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAL64469.1 - 4e-52 176.5 3.3 5.2e-52 176.1 3.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAL64469.1 - 8.8e-08 32.3 0.7 1.1e-07 31.9 0.7 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AAL64469.1 - 0.00067 19.2 0.7 0.0025 17.3 0.4 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family MEF2_binding PF09047.10 AAL64469.1 - 0.024 14.5 0.1 0.061 13.2 0.1 1.6 1 0 0 1 1 1 0 MEF2 binding PAS_3 PF08447.12 AAL64469.1 - 0.12 12.7 0.0 0.81 10.0 0.0 2.3 3 0 0 3 3 3 0 PAS fold DUF1641 PF07849.11 AAL64470.1 - 2e-15 56.4 0.6 3.8e-15 55.5 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1641) HALZ PF02183.18 AAL64470.1 - 0.014 15.6 1.1 0.025 14.8 1.1 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper DASH_Dad3 PF08656.10 AAL64470.1 - 0.1 12.7 0.1 5.8 7.1 0.0 2.3 2 0 0 2 2 2 0 DASH complex subunit Dad3 Pyr_redox_2 PF07992.14 AAL64471.1 - 2.2e-17 63.3 0.0 1.2e-16 60.9 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAL64471.1 - 5.1e-05 23.7 0.1 0.013 16.0 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AAL64471.1 - 0.065 13.5 1.3 3.1 8.1 0.0 3.1 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain NrfD PF03916.14 AAL64472.1 - 1.1e-13 51.6 18.6 1.1e-13 51.6 18.6 2.0 2 0 0 2 2 2 1 Polysulphide reductase, NrfD Fer4_7 PF12838.7 AAL64473.1 - 1.8e-19 70.0 17.8 6.1e-10 39.5 3.2 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 AAL64473.1 - 3.3e-15 55.4 33.9 1.8e-07 30.9 1.9 4.7 4 1 0 4 4 4 3 4Fe-4S binding domain Fer4_9 PF13187.6 AAL64473.1 - 5.8e-15 55.2 12.8 5.7e-07 29.6 3.6 3.0 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_11 PF13247.6 AAL64473.1 - 7.3e-15 54.9 14.3 2.3e-09 37.3 4.7 2.9 2 1 0 3 3 3 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 AAL64473.1 - 1e-13 51.5 8.1 8.3e-07 29.4 0.1 2.4 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 AAL64473.1 - 1.6e-13 49.8 39.2 4e-08 32.7 2.8 5.6 6 0 0 6 6 6 4 4Fe-4S binding domain Fer4_10 PF13237.6 AAL64473.1 - 2.2e-12 46.9 23.8 3.4e-06 27.1 7.0 4.1 2 1 1 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAL64473.1 - 1.8e-10 40.2 34.4 3e-05 23.8 1.2 4.6 4 1 0 4 4 4 3 4Fe-4S binding domain Fer4_3 PF12798.7 AAL64473.1 - 5.4e-09 36.4 37.8 0.0059 17.5 1.4 4.2 4 0 0 4 4 4 4 4Fe-4S binding domain Fer4_17 PF13534.6 AAL64473.1 - 2.3e-08 34.4 16.5 0.00023 21.6 0.8 3.8 3 2 1 4 4 4 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 AAL64473.1 - 1.7e-07 31.3 21.4 0.00029 20.9 0.7 4.5 5 0 0 5 5 5 3 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAL64473.1 - 6.4e-06 27.0 20.7 0.11 13.5 2.7 4.4 4 1 0 4 4 4 3 4Fe-4S double cluster binding domain Fer4_4 PF12800.7 AAL64473.1 - 0.00016 21.9 36.2 0.0013 19.1 1.8 4.6 5 0 0 5 5 4 2 4Fe-4S binding domain Fer4_15 PF13459.6 AAL64473.1 - 0.0018 19.0 4.5 0.014 16.1 0.5 3.6 5 0 0 5 5 4 2 4Fe-4S single cluster domain Fer4_13 PF13370.6 AAL64473.1 - 0.013 16.1 0.3 0.013 16.1 0.3 3.9 4 0 0 4 4 3 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_22 PF17179.4 AAL64473.1 - 5.4 7.9 24.1 0.41 11.5 1.6 4.0 3 1 1 4 4 4 0 4Fe-4S dicluster domain Molydop_binding PF01568.21 AAL64474.1 - 3e-12 46.5 0.0 8.4e-09 35.4 0.0 2.4 2 0 0 2 2 2 2 Molydopterin dinucleotide binding domain Molybdopterin PF00384.22 AAL64475.1 - 2.5e-37 128.9 0.0 4.4e-37 128.1 0.0 1.3 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Molybdop_Fe4S4 PF04879.16 AAL64475.1 - 2.2e-08 33.9 0.5 4.3e-08 33.0 0.5 1.5 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain TAT_signal PF10518.9 AAL64475.1 - 0.019 14.8 0.0 0.056 13.3 0.0 1.9 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Adeno_PIX PF03955.14 AAL64475.1 - 0.11 12.7 2.0 1.5 9.0 1.0 2.6 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) FDC-SP PF15215.6 AAL64475.1 - 0.29 11.7 2.0 0.83 10.2 2.0 1.7 1 0 0 1 1 1 0 Follicular dendritic cell secreted peptide LPP PF04728.13 AAL64479.1 - 0.013 15.8 0.4 0.1 13.0 0.3 2.2 1 1 1 2 2 2 0 Lipoprotein leucine-zipper Caps_synth PF05704.12 AAL64479.1 - 0.03 13.7 0.0 0.036 13.5 0.0 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein FlaC_arch PF05377.11 AAL64479.1 - 0.039 14.3 0.5 0.12 12.8 0.2 1.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) WD40_alt PF14077.6 AAL64479.1 - 0.039 13.8 0.1 0.11 12.3 0.1 1.7 1 0 0 1 1 1 0 Alternative WD40 repeat motif DUF948 PF06103.11 AAL64479.1 - 0.14 12.4 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DivIC PF04977.15 AAL64479.1 - 0.2 11.5 3.2 0.85 9.4 0.3 2.8 2 1 0 2 2 2 0 Septum formation initiator NPV_P10 PF05531.12 AAL64479.1 - 0.2 12.1 0.8 0.7 10.4 0.1 2.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Asp_protease PF09668.10 AAL64481.1 - 0.13 12.1 0.0 0.13 12.1 0.0 1.0 1 0 0 1 1 1 0 Aspartyl protease Peptidase_U4 PF03419.13 AAL64481.1 - 0.16 11.3 0.0 0.16 11.2 0.0 1.0 1 0 0 1 1 1 0 Sporulation factor SpoIIGA UPF0175 PF03683.13 AAL64482.1 - 0.012 15.3 0.1 0.032 13.9 0.0 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0175) ATPase_2 PF01637.18 AAL64485.1 - 1.8e-45 155.6 0.0 2.4e-45 155.3 0.0 1.1 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 AAL64485.1 - 6.2e-07 29.9 0.1 1.5e-06 28.7 0.0 1.8 2 1 0 2 2 1 1 AAA ATPase domain NB-ARC PF00931.22 AAL64485.1 - 0.0009 18.5 0.0 0.036 13.3 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain NACHT PF05729.12 AAL64485.1 - 0.0029 17.5 0.0 0.0052 16.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 AAL64485.1 - 0.003 17.8 0.0 0.0062 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 AAL64485.1 - 0.0073 16.7 0.0 0.013 15.9 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 AAL64485.1 - 0.0073 16.3 0.2 0.045 13.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 AAL64485.1 - 0.0092 16.0 0.0 0.029 14.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.6 AAL64485.1 - 0.011 15.9 0.0 0.038 14.1 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain TniB PF05621.11 AAL64485.1 - 0.011 15.2 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein RNA_helicase PF00910.22 AAL64485.1 - 0.012 16.0 0.0 0.022 15.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Rad17 PF03215.15 AAL64485.1 - 0.029 14.3 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_28 PF13521.6 AAL64485.1 - 0.041 14.1 0.0 0.083 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 AAL64485.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 AAL64485.1 - 0.071 12.8 0.0 0.24 11.1 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain Pox_A32 PF04665.12 AAL64485.1 - 0.079 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein ATPase PF06745.13 AAL64485.1 - 0.081 12.3 0.1 0.69 9.2 0.0 2.2 2 0 0 2 2 2 0 KaiC ABC_tran PF00005.27 AAL64485.1 - 0.11 13.0 0.0 0.2 12.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 AAL64485.1 - 0.14 12.7 0.0 0.48 11.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AAL64485.1 - 0.14 11.9 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 AAL64485.1 - 0.2 11.4 0.0 0.5 10.2 0.0 1.6 2 0 0 2 2 2 0 Bacterial dnaA protein Adeno_IVa2 PF02456.15 AAL64485.1 - 0.27 10.0 0.0 0.5 9.1 0.0 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein gag-asp_proteas PF13975.6 AAL64486.1 - 1.6e-09 38.2 0.0 1.9e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 AAL64486.1 - 4.8e-08 33.5 0.0 7.5e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 AAL64486.1 - 2e-05 24.4 0.0 2.3e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease HupF_HypC PF01455.18 AAL64486.1 - 0.22 11.7 1.0 0.69 10.1 0.3 1.9 2 0 0 2 2 2 0 HupF/HypC family DUF1697 PF08002.11 AAL64487.1 - 0.055 13.9 0.0 0.078 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1697) Molybdopterin PF00384.22 AAL64489.1 - 2.6e-51 175.0 0.0 1.4e-50 172.5 0.0 2.0 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 AAL64489.1 - 4.2e-12 46.1 0.0 8.7e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain CDC48_N PF02359.18 AAL64489.1 - 0.014 15.6 0.0 0.029 14.5 0.0 1.5 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain Molybdop_Fe4S4 PF04879.16 AAL64489.1 - 0.039 14.0 0.0 0.079 13.0 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin oxidoreductase Fe4S4 domain Fer4_11 PF13247.6 AAL64490.1 - 2.1e-22 79.1 8.9 2.1e-22 79.1 8.9 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AAL64490.1 - 2.1e-16 60.3 22.8 1.6e-09 38.2 6.4 2.7 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 AAL64490.1 - 3.9e-14 51.8 29.7 7.1e-07 28.8 2.1 4.6 4 0 0 4 4 4 4 4Fe-4S binding domain Fer4_6 PF12837.7 AAL64490.1 - 8.1e-13 47.8 34.3 2.4e-05 24.2 2.1 4.3 4 0 0 4 4 4 4 4Fe-4S binding domain Fer4_9 PF13187.6 AAL64490.1 - 3.1e-11 43.3 21.8 8.9e-06 25.8 6.8 2.9 2 2 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAL64490.1 - 6.3e-10 39.0 27.1 0.00049 20.2 10.3 3.9 2 1 2 4 4 4 4 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAL64490.1 - 1.6e-07 31.0 32.9 0.0019 18.2 1.4 4.5 4 1 0 4 4 4 3 4Fe-4S binding domain Fer4_16 PF13484.6 AAL64490.1 - 1.8e-06 28.7 23.8 0.16 12.9 0.6 4.2 3 1 1 4 4 4 3 4Fe-4S double cluster binding domain Fer4_4 PF12800.7 AAL64490.1 - 4.4e-06 26.8 34.9 0.0098 16.3 2.6 4.4 4 1 0 4 4 4 3 4Fe-4S binding domain Fer4_3 PF12798.7 AAL64490.1 - 1.1e-05 26.0 44.1 0.051 14.5 7.3 4.4 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4_17 PF13534.6 AAL64490.1 - 4.3e-05 24.0 23.3 0.074 13.6 4.0 3.9 1 1 3 4 4 4 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 AAL64490.1 - 7e-05 23.2 27.2 0.01 16.2 9.7 3.6 2 2 0 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 AAL64490.1 - 8.9e-05 22.6 30.0 0.0014 18.7 0.5 3.7 2 1 1 3 3 3 3 4Fe-4S dicluster domain Fer4_15 PF13459.6 AAL64490.1 - 0.097 13.4 0.7 0.097 13.4 0.7 3.5 3 1 1 4 4 4 0 4Fe-4S single cluster domain Fer4_18 PF13746.6 AAL64490.1 - 0.11 12.7 24.9 0.4 10.9 7.5 3.7 2 1 2 4 4 4 0 4Fe-4S dicluster domain Rieske_3 PF18465.1 AAL64490.1 - 0.88 9.9 5.3 0.64 10.3 0.6 2.2 2 0 0 2 2 2 0 Rieske 3Fe-4S Fer4_22 PF17179.4 AAL64490.1 - 4.8 8.1 21.8 0.82 10.6 1.1 3.6 3 1 1 4 4 3 0 4Fe-4S dicluster domain NrfD PF03916.14 AAL64491.1 - 1.1e-24 87.6 36.0 1.5e-24 87.2 36.0 1.1 1 0 0 1 1 1 1 Polysulphide reductase, NrfD NrfD_2 PF14589.6 AAL64491.1 - 1.7e-05 24.9 42.8 2.7e-05 24.3 42.8 1.3 1 1 0 1 1 1 1 Polysulfide reductase PaREP1 PF05942.11 AAL64492.1 - 6.8e-27 93.7 4.3 8.4e-27 93.4 4.3 1.1 1 0 0 1 1 1 1 Archaeal PaREP1/PaREP8 family Peptidase_M24 PF00557.24 AAL64492.1 - 0.019 14.7 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Metallopeptidase family M24 HEPN PF05168.14 AAL64492.1 - 0.81 9.8 8.5 1.3 9.2 6.0 2.0 2 0 0 2 2 2 0 HEPN domain CBS PF00571.28 AAL64493.1 - 1e-28 99.5 4.7 1.7e-14 53.9 0.4 2.1 2 0 0 2 2 2 2 CBS domain IF3_N PF05198.16 AAL64493.1 - 0.054 13.8 0.3 0.51 10.6 0.1 2.2 2 0 0 2 2 2 0 Translation initiation factor IF-3, N-terminal domain AMP-binding PF00501.28 AAL64494.1 - 1.1e-85 287.9 0.0 1.4e-85 287.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAL64494.1 - 1.1e-28 100.0 0.3 2.6e-28 98.8 0.3 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 AAL64494.1 - 1.7e-10 40.7 4.8 1.7e-10 40.7 4.8 1.9 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus XRN1_DBM PF18245.1 AAL64494.1 - 0.13 12.3 0.3 26 5.0 0.0 3.0 2 0 0 2 2 2 0 5-3 exonuclease XRN1 DCP1-binding motif CBS PF00571.28 AAL64495.1 - 1e-28 99.6 1.5 1.7e-14 54.0 0.4 2.2 2 0 0 2 2 2 2 CBS domain GerE PF00196.19 AAL64495.1 - 0.075 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family GAF_2 PF13185.6 AAL64495.1 - 0.083 13.2 0.3 8.8 6.6 0.0 2.3 1 1 0 2 2 2 0 GAF domain MFS_1 PF07690.16 AAL64496.1 - 8.7e-22 77.5 68.6 1.8e-13 50.1 39.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AAL64496.1 - 3.1e-21 75.8 35.3 1.9e-15 56.7 19.6 2.2 1 1 0 2 2 2 2 Sugar (and other) transporter CBS PF00571.28 AAL64496.1 - 8.6e-09 35.7 0.0 0.0016 18.8 0.0 2.5 2 0 0 2 2 2 2 CBS domain AMP-binding PF00501.28 AAL64497.1 - 9.7e-97 324.2 0.0 1.2e-96 324.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAL64497.1 - 3.6e-30 104.8 0.6 8.6e-30 103.5 0.6 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 AAL64497.1 - 1.7e-21 75.8 1.5 6.2e-21 74.1 1.5 2.1 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Homoserine_dh PF00742.19 AAL64498.1 - 3.3e-33 115.0 0.0 2e-32 112.5 0.0 2.0 1 1 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 AAL64498.1 - 3e-05 24.7 0.0 5.8e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 AAL64498.1 - 0.017 14.9 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase PaREP1 PF05942.11 AAL64499.1 - 2.1e-26 92.1 0.7 2.6e-26 91.8 0.7 1.1 1 0 0 1 1 1 1 Archaeal PaREP1/PaREP8 family Blt1_C PF17183.4 AAL64499.1 - 0.069 12.8 0.1 0.2 11.3 0.0 1.8 2 0 0 2 2 2 0 Get5 carboxyl domain DUF86 PF01934.17 AAL64500.1 - 9.9e-16 57.7 0.0 1.2e-15 57.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF86 DUF2250 PF10007.9 AAL64500.1 - 0.005 16.9 0.0 0.0059 16.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) PhoU_div PF01865.16 AAL64500.1 - 0.04 13.2 0.0 0.05 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF47 Semialdhyde_dh PF01118.24 AAL64504.1 - 4.3e-35 120.8 0.0 9.2e-35 119.7 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.18 AAL64504.1 - 3.1e-32 112.1 0.0 5.3e-32 111.4 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain DXP_reductoisom PF02670.16 AAL64504.1 - 0.0062 17.3 0.0 0.013 16.2 0.0 1.6 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DapB_N PF01113.20 AAL64504.1 - 0.01 16.0 0.0 0.081 13.0 0.0 2.1 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Sacchrp_dh_NADP PF03435.18 AAL64504.1 - 0.046 14.0 0.0 0.083 13.1 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain RhodobacterPufX PF11511.8 AAL64504.1 - 0.061 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Intrinsic membrane protein PufX GFO_IDH_MocA PF01408.22 AAL64504.1 - 0.14 13.0 0.0 0.36 11.7 0.0 1.7 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Epimerase PF01370.21 AAL64504.1 - 0.14 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Fe-S_biosyn PF01521.20 AAL64504.1 - 0.16 12.2 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 Iron-sulphur cluster biosynthesis AA_kinase PF00696.28 AAL64505.1 - 3e-38 131.8 0.0 4.4e-38 131.2 0.0 1.3 1 0 0 1 1 1 1 Amino acid kinase family PRTase_1 PF11202.8 AAL64505.1 - 0.061 12.5 0.0 0.096 11.9 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase (PRTase) PALP PF00291.25 AAL64506.1 - 3.1e-68 230.3 3.3 3.8e-68 230.0 3.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ApoL PF05461.11 AAL64507.1 - 0.074 12.4 0.1 0.1 11.9 0.1 1.1 1 0 0 1 1 1 0 Apolipoprotein L Semialdhyde_dh PF01118.24 AAL64508.1 - 2.8e-32 111.7 0.0 4.9e-32 110.9 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.18 AAL64508.1 - 1.7e-12 47.8 0.0 4.8e-12 46.3 0.0 1.7 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Epimerase PF01370.21 AAL64508.1 - 0.0093 15.4 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 AAL64508.1 - 0.011 15.9 0.0 0.019 15.1 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Sacchrp_dh_NADP PF03435.18 AAL64508.1 - 0.017 15.4 0.0 0.027 14.7 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GFO_IDH_MocA PF01408.22 AAL64508.1 - 0.045 14.6 0.0 0.13 13.1 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 AAL64508.1 - 0.057 14.0 0.0 0.17 12.5 0.0 1.8 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AA_kinase PF00696.28 AAL64509.1 - 9.1e-31 107.3 0.6 1.2e-30 106.9 0.6 1.1 1 0 0 1 1 1 1 Amino acid kinase family Cytadhesin_P30 PF07271.11 AAL64509.1 - 0.069 12.7 0.0 0.094 12.3 0.0 1.2 1 0 0 1 1 1 0 Cytadhesin P30/P32 HypA PF01155.19 AAL64510.1 - 1.6e-06 28.1 0.3 1.7e-06 28.0 0.3 1.0 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 AAL64510.1 - 6.3e-06 26.2 0.3 8.7e-06 25.8 0.3 1.2 1 0 0 1 1 1 1 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 AAL64510.1 - 3.4e-05 23.3 1.2 6.3e-05 22.4 1.2 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding zinc_ribbon_4 PF13717.6 AAL64510.1 - 6.4e-05 22.8 1.3 0.0042 17.0 1.4 2.2 1 1 1 2 2 2 2 zinc-ribbon domain zinc_ribbon_5 PF13719.6 AAL64510.1 - 0.00067 19.4 0.3 0.16 11.8 0.0 2.2 2 0 0 2 2 2 1 zinc-ribbon domain Prok-RING_1 PF14446.6 AAL64510.1 - 0.0014 18.5 2.6 0.0033 17.3 2.6 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 1 zf-CHCC PF10276.9 AAL64510.1 - 0.0018 18.3 0.4 2 8.5 0.0 2.2 2 0 0 2 2 2 2 Zinc-finger domain zf-CSL PF05207.13 AAL64510.1 - 0.0019 17.9 1.0 0.0021 17.8 0.3 1.5 2 0 0 2 2 2 1 CSL zinc finger zf-HYPF PF07503.12 AAL64510.1 - 0.007 16.1 0.7 0.61 9.9 0.1 2.1 2 0 0 2 2 2 1 HypF finger DNA_RNApol_7kD PF03604.13 AAL64510.1 - 0.0085 15.7 0.6 3.9 7.2 0.1 2.2 2 0 0 2 2 2 2 DNA directed RNA polymerase, 7 kDa subunit DUF1451 PF07295.11 AAL64510.1 - 0.03 14.4 0.2 0.036 14.1 0.2 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain PhnA_Zn_Ribbon PF08274.12 AAL64510.1 - 0.03 14.3 0.8 0.048 13.6 0.8 1.3 1 0 0 1 1 1 0 PhnA Zinc-Ribbon zf-IS66 PF13005.7 AAL64510.1 - 0.034 14.5 0.8 3.2 8.2 0.0 2.1 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 Ogr_Delta PF04606.12 AAL64510.1 - 0.035 14.1 0.2 2.5 8.1 0.1 2.2 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger DZR PF12773.7 AAL64510.1 - 0.035 14.1 0.5 0.055 13.5 0.5 1.3 1 1 0 1 1 1 0 Double zinc ribbon Elf1 PF05129.13 AAL64510.1 - 0.039 14.0 0.7 1.1 9.3 0.1 2.1 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-C2H2_3 PF13878.6 AAL64510.1 - 0.039 13.8 3.0 3.5 7.5 0.1 2.2 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO DUF3797 PF12677.7 AAL64510.1 - 0.059 13.3 1.2 0.44 10.5 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3797) Zn_ribbon_SprT PF17283.2 AAL64510.1 - 0.065 13.1 1.2 0.84 9.6 0.1 2.1 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Lar_restr_allev PF14354.6 AAL64510.1 - 0.068 13.6 1.2 1.4 9.3 0.1 2.1 1 1 1 2 2 2 0 Restriction alleviation protein Lar zf-Sec23_Sec24 PF04810.15 AAL64510.1 - 0.07 13.2 0.0 2.2 8.4 0.0 2.1 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-RING_7 PF02591.15 AAL64510.1 - 0.071 13.3 1.1 0.48 10.6 0.1 2.2 2 0 0 2 2 2 0 C4-type zinc ribbon domain RNA_POL_M_15KD PF02150.16 AAL64510.1 - 0.075 12.9 0.4 2.2 8.2 0.0 2.1 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit zf-NADH-PPase PF09297.11 AAL64510.1 - 0.081 12.6 0.9 5.3 6.8 0.2 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Cys_rich_CPXG PF14255.6 AAL64510.1 - 0.095 12.6 2.1 5.5 7.0 0.1 2.2 1 1 1 2 2 2 0 Cysteine-rich CPXCG zf-C2H2_4 PF13894.6 AAL64510.1 - 0.12 13.3 0.5 5.3 8.2 0.0 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger A2L_zn_ribbon PF08792.10 AAL64510.1 - 0.13 12.1 1.4 0.93 9.3 1.4 2.0 1 1 0 1 1 1 0 A2L zinc ribbon domain DUF983 PF06170.12 AAL64510.1 - 0.14 12.5 1.4 3.4 8.2 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF983) zf-C2H2 PF00096.26 AAL64510.1 - 0.22 12.0 0.6 8.6 7.0 0.0 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type CpXC PF14353.6 AAL64510.1 - 0.25 11.4 1.7 6.3 6.9 1.8 2.0 1 1 1 2 2 2 0 CpXC protein zf-C2H2_6 PF13912.6 AAL64510.1 - 0.92 9.6 3.2 16 5.6 0.8 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-HIT PF04438.16 AAL64510.1 - 1.6 8.7 6.0 4.1 7.4 0.9 2.1 2 0 0 2 2 2 0 HIT zinc finger Arginosuc_synth PF00764.19 AAL64511.1 - 3.4e-122 408.5 0.0 4.2e-122 408.2 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase zf-ribbon_3 PF13248.6 AAL64512.1 - 4.1e-05 22.8 7.9 0.028 13.8 1.5 2.4 2 1 0 2 2 2 2 zinc-ribbon domain zf_UBZ PF18439.1 AAL64512.1 - 0.0037 16.8 6.7 0.39 10.3 0.7 2.3 2 1 0 2 2 2 2 Ubiquitin-Binding Zinc Finger zinc_ribbon_2 PF13240.6 AAL64512.1 - 0.0053 16.4 11.8 0.028 14.1 0.6 3.0 2 1 1 3 3 3 2 zinc-ribbon domain zf_Rg PF17915.1 AAL64512.1 - 0.01 15.2 4.3 0.24 10.8 0.1 2.1 2 0 0 2 2 2 0 Reverse gyrase zinc finger Sgf11 PF08209.11 AAL64512.1 - 0.015 14.8 9.2 0.024 14.2 0.3 2.9 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) DZR PF12773.7 AAL64512.1 - 0.019 15.0 7.0 0.082 12.9 7.0 1.9 1 1 0 1 1 1 0 Double zinc ribbon zf-NADH-PPase PF09297.11 AAL64512.1 - 0.038 13.7 3.5 3.3 7.4 0.1 2.5 2 1 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Auto_anti-p27 PF06677.12 AAL64512.1 - 0.042 14.0 3.7 0.76 10.0 0.3 2.2 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-TFIIB PF13453.6 AAL64512.1 - 0.056 12.8 7.8 0.5 9.7 0.1 2.3 2 1 0 2 2 2 0 Transcription factor zinc-finger Acetone_carb_G PF08882.11 AAL64512.1 - 0.07 13.3 2.5 0.14 12.3 2.5 1.6 1 1 0 1 1 1 0 Acetone carboxylase gamma subunit zf_C2H2_10 PF18414.1 AAL64512.1 - 0.11 12.0 1.4 0.11 12.0 1.4 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger zinc-ribbons_6 PF07191.12 AAL64512.1 - 0.15 12.1 6.1 0.57 10.2 6.1 1.9 1 1 0 1 1 1 0 zinc-ribbons DUF35_N PF12172.8 AAL64512.1 - 0.17 11.8 4.6 1.6 8.7 0.4 2.3 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-HYPF PF07503.12 AAL64512.1 - 0.2 11.5 9.5 2.8 7.8 9.6 2.1 1 1 0 1 1 1 0 HypF finger zf-ACC PF17848.1 AAL64512.1 - 0.3 11.2 0.8 0.3 11.2 0.8 2.4 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain TF_Zn_Ribbon PF08271.12 AAL64512.1 - 0.31 10.6 11.2 0.62 9.6 2.7 2.3 2 1 0 2 2 2 0 TFIIB zinc-binding FYDLN_acid PF09538.10 AAL64512.1 - 0.51 11.0 5.3 2.3 8.9 1.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) Zn-ribbon_8 PF09723.10 AAL64512.1 - 0.57 10.4 9.9 3.8 7.7 0.7 2.4 1 1 1 2 2 2 0 Zinc ribbon domain YacG PF03884.14 AAL64512.1 - 0.61 9.9 8.4 0.87 9.4 2.1 2.2 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG zinc_ribbon_10 PF10058.9 AAL64512.1 - 0.69 9.7 9.5 6.7 6.5 9.5 2.1 1 1 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein Zn_Tnp_IS1595 PF12760.7 AAL64512.1 - 0.82 9.7 11.2 5.9 6.9 1.5 2.1 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Rad50_zn_hook PF04423.14 AAL64512.1 - 2.3 8.1 7.4 0.37 10.7 0.7 2.1 2 0 0 2 2 2 0 Rad50 zinc hook motif OrfB_Zn_ribbon PF07282.11 AAL64512.1 - 2.5 8.1 8.0 10 6.1 0.3 2.1 1 1 1 2 2 2 0 Putative transposase DNA-binding domain Lyase_1 PF00206.20 AAL64513.1 - 1.2e-35 123.4 0.0 1.7e-35 122.9 0.0 1.1 1 0 0 1 1 1 1 Lyase DUF2680 PF10925.8 AAL64513.1 - 0.0025 17.8 0.1 0.0054 16.7 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2680) ASL_C2 PF14698.6 AAL64513.1 - 0.085 13.6 0.4 0.65 10.8 0.0 2.5 2 0 0 2 2 2 0 Argininosuccinate lyase C-terminal Endonuc-MspI PF09208.10 AAL64513.1 - 0.11 11.8 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease MspI DUF4088 PF13317.6 AAL64513.1 - 0.17 11.4 1.0 1.6 8.3 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4088) DUF998 PF06197.13 AAL64514.1 - 4.7e-31 107.8 20.4 5.3e-31 107.6 20.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF998) DoxX_2 PF13564.6 AAL64514.1 - 3.2 7.9 15.6 0.2 11.8 4.9 2.4 1 1 1 2 2 2 0 DoxX-like family Zip PF02535.22 AAL64514.1 - 3.2 6.9 9.6 1.4 8.0 0.8 2.3 2 1 0 2 2 2 0 ZIP Zinc transporter ABC_tran PF00005.27 AAL64515.1 - 1.4e-34 119.5 0.0 2e-34 119.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAL64515.1 - 1.1e-09 38.5 2.9 0.00026 20.9 0.3 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system TOBE_2 PF08402.10 AAL64515.1 - 1.3e-08 34.9 0.1 4.9e-08 33.0 0.0 2.1 3 0 0 3 3 2 1 TOBE domain AAA_22 PF13401.6 AAL64515.1 - 3.1e-05 24.3 1.0 0.0003 21.1 1.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAL64515.1 - 0.00013 21.6 0.0 0.00025 20.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AAL64515.1 - 0.00035 21.0 0.2 0.00054 20.4 0.2 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 AAL64515.1 - 0.002 18.1 0.2 0.014 15.4 0.1 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 AAL64515.1 - 0.0053 16.2 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI SbcCD_C PF13558.6 AAL64515.1 - 0.0057 16.9 0.1 0.1 12.9 0.1 2.2 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 AAL64515.1 - 0.0085 16.0 0.1 0.018 15.0 0.1 1.5 2 0 0 2 2 2 1 RsgA GTPase AAA PF00004.29 AAL64515.1 - 0.0088 16.5 0.2 0.11 12.9 0.2 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 AAL64515.1 - 0.018 14.7 0.3 0.057 13.1 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein NACHT PF05729.12 AAL64515.1 - 0.035 14.0 0.0 0.061 13.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 AAL64515.1 - 0.035 13.8 0.0 0.097 12.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 AAL64515.1 - 0.04 13.3 0.1 2.4 7.5 0.1 2.1 2 0 0 2 2 2 0 Bacterial TniB protein AAA_23 PF13476.6 AAL64515.1 - 0.047 14.2 0.0 0.088 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 AAL64515.1 - 0.095 12.1 0.1 7.1 6.0 0.1 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain MIT_C PF16565.5 AAL64515.1 - 0.11 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Phospholipase D-like domain at C-terminus of MIT AAA_33 PF13671.6 AAL64515.1 - 0.12 12.5 0.3 0.27 11.4 0.1 1.6 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 AAL64515.1 - 0.13 11.3 0.1 0.21 10.6 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein G-alpha PF00503.20 AAL64515.1 - 0.22 10.7 0.0 0.33 10.1 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_19 PF13245.6 AAL64515.1 - 0.4 11.0 1.0 2.9 8.2 1.0 2.0 1 1 0 1 1 1 0 AAA domain BPD_transp_1 PF00528.22 AAL64516.1 - 1.1e-12 48.1 18.2 1.1e-12 48.1 18.2 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 AAL64517.1 - 1.1e-08 35.0 16.4 1.1e-08 35.0 16.4 2.2 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF1240 PF06836.12 AAL64517.1 - 0.051 14.1 3.4 0.11 13.0 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1240) Succ_CoA_lig PF13607.6 AAL64518.1 - 1.7e-46 157.4 1.5 2.7e-45 153.6 0.3 2.3 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 AAL64518.1 - 4e-21 75.7 1.1 6.8e-21 74.9 0.1 1.9 3 0 0 3 3 3 1 CoA binding domain CoA_binding PF02629.19 AAL64518.1 - 9.6e-08 32.6 0.4 2e-07 31.6 0.4 1.5 1 0 0 1 1 1 1 CoA binding domain Thioredoxin_2 PF13098.6 AAL64519.1 - 0.0055 17.1 0.1 0.015 15.8 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_4 PF13462.6 AAL64519.1 - 0.011 15.9 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin DSBA PF01323.20 AAL64519.1 - 5.7 6.7 5.4 0.75 9.5 0.9 1.7 2 0 0 2 2 2 0 DSBA-like thioredoxin domain CBS PF00571.28 AAL64520.1 - 6.6e-25 87.3 1.0 4.4e-13 49.5 0.1 2.2 2 0 0 2 2 2 2 CBS domain IF3_N PF05198.16 AAL64520.1 - 0.083 13.2 1.5 3.6 7.9 0.1 2.7 2 1 1 3 3 3 0 Translation initiation factor IF-3, N-terminal domain US22 PF02393.16 AAL64520.1 - 0.18 12.1 0.1 0.37 11.0 0.1 1.7 1 1 0 1 1 1 0 US22 like VWA_2 PF13519.6 AAL64521.1 - 5.8e-05 23.7 0.1 0.00046 20.8 0.0 2.4 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 AAL64521.1 - 0.00055 19.4 0.3 0.0035 16.8 0.3 2.0 1 1 0 1 1 1 1 VWA domain containing CoxE-like protein VWA PF00092.28 AAL64521.1 - 0.018 15.3 1.6 0.052 13.8 0.3 2.4 2 2 0 2 2 2 0 von Willebrand factor type A domain DUF5104 PF17117.5 AAL64521.1 - 0.065 13.7 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5104) AAA_5 PF07728.14 AAL64522.1 - 4e-26 91.7 0.0 9.1e-26 90.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 AAL64522.1 - 2.9e-06 27.7 0.0 3.5e-05 24.2 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AAL64522.1 - 0.00053 20.4 0.0 0.0035 17.8 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_3 PF07726.11 AAL64522.1 - 0.00062 19.6 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 AAL64522.1 - 0.0014 18.0 0.0 0.0041 16.5 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 AAL64522.1 - 0.002 17.9 0.0 0.0043 16.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.12 AAL64522.1 - 0.033 13.9 1.7 3 7.6 0.2 2.9 2 1 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 AAL64522.1 - 0.035 13.6 0.0 0.067 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 AAL64522.1 - 0.065 12.9 0.0 0.14 11.9 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 AAL64522.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AAL64522.1 - 0.16 12.2 0.1 4.7 7.5 0.0 2.6 2 1 1 3 3 3 0 AAA domain NurA PF09376.10 AAL64523.1 - 6.3e-70 235.6 0.8 8.1e-70 235.3 0.8 1.1 1 0 0 1 1 1 1 NurA domain DUF87 PF01935.17 AAL64524.1 - 3.6e-43 148.3 0.0 5.2e-43 147.8 0.0 1.2 1 0 0 1 1 1 1 Helicase HerA, central domain HAS-barrel PF09378.10 AAL64524.1 - 5e-13 49.0 0.1 5.7e-12 45.6 0.1 2.6 2 0 0 2 2 2 1 HAS barrel domain TrwB_AAD_bind PF10412.9 AAL64524.1 - 1.6e-07 30.6 0.0 4.4e-05 22.6 0.0 2.2 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain DUF853 PF05872.12 AAL64524.1 - 2.4e-06 26.4 0.0 0.03 12.9 0.0 2.2 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF853) ResIII PF04851.15 AAL64524.1 - 4.7e-06 26.7 0.0 9.4e-05 22.5 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T4SS-DNA_transf PF02534.14 AAL64524.1 - 7.6e-05 21.7 0.0 0.00024 20.1 0.0 1.7 2 0 0 2 2 2 1 Type IV secretory system Conjugative DNA transfer FtsK_SpoIIIE PF01580.18 AAL64524.1 - 0.001 18.4 0.0 0.61 9.4 0.0 2.5 2 1 0 2 2 2 2 FtsK/SpoIIIE family AAA_10 PF12846.7 AAL64524.1 - 0.013 14.5 0.0 0.035 13.0 0.0 1.6 2 0 0 2 2 2 0 AAA-like domain AAA PF00004.29 AAL64524.1 - 0.022 15.2 0.1 0.076 13.4 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AAL64524.1 - 0.023 15.0 0.0 2.4 8.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 AAL64524.1 - 0.026 14.4 0.0 0.049 13.5 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Vps36-NZF-N PF16988.5 AAL64524.1 - 0.027 13.9 0.1 0.056 12.9 0.1 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain DEAD PF00270.29 AAL64524.1 - 0.061 13.1 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase Zot PF05707.12 AAL64524.1 - 0.07 12.8 0.0 0.73 9.4 0.0 2.1 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) Pox_A32 PF04665.12 AAL64524.1 - 0.13 11.7 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein T2SSE PF00437.20 AAL64524.1 - 0.16 11.0 0.0 0.36 9.9 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Metallophos PF00149.28 AAL64525.1 - 1.2e-11 45.5 0.0 2.4e-11 44.6 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AAL64525.1 - 3.6e-08 33.8 0.0 8.6e-08 32.5 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SMC_N PF02463.19 AAL64526.1 - 1.3e-23 83.6 0.0 2.4e-23 82.7 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AAL64526.1 - 5.3e-16 59.7 56.8 5.4e-09 36.9 41.7 4.9 1 1 1 2 2 2 1 AAA domain AAA_21 PF13304.6 AAL64526.1 - 4.6e-10 39.8 10.2 3.9e-06 26.9 0.0 3.0 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AAL64526.1 - 1e-09 38.6 21.9 2.3e-06 27.6 6.2 3.7 2 2 0 2 2 2 2 AAA ATPase domain AAA_13 PF13166.6 AAL64526.1 - 6.7e-08 31.7 36.9 4.8e-05 22.2 14.1 3.4 2 1 0 3 3 3 2 AAA domain Spc7 PF08317.11 AAL64526.1 - 4.7e-07 29.0 62.0 0.024 13.5 14.0 4.2 2 2 2 4 4 4 4 Spc7 kinetochore protein AAA_29 PF13555.6 AAL64526.1 - 7.1e-07 28.9 0.0 1.2e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 AAL64526.1 - 4.1e-06 27.4 8.0 0.013 16.0 1.3 3.9 3 1 0 3 3 2 2 ABC transporter AAA_27 PF13514.6 AAL64526.1 - 7.1e-05 22.5 0.0 7.1e-05 22.5 0.0 4.4 4 2 1 5 5 5 1 AAA domain GAS PF13851.6 AAL64526.1 - 8.2e-05 22.0 64.1 0.00016 21.1 16.7 4.2 2 2 2 4 4 4 2 Growth-arrest specific micro-tubule binding FlaC_arch PF05377.11 AAL64526.1 - 0.00034 21.0 34.4 0.029 14.7 1.2 6.7 6 0 0 6 6 6 2 Flagella accessory protein C (FlaC) NPV_P10 PF05531.12 AAL64526.1 - 0.00063 20.1 7.5 5.4 7.6 0.1 5.6 5 1 1 6 6 5 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.10 AAL64526.1 - 0.0007 19.8 8.9 0.0007 19.8 8.9 3.8 3 1 1 4 4 3 1 Fibrinogen alpha/beta chain family Nup54 PF13874.6 AAL64526.1 - 0.0026 17.9 37.7 0.08 13.1 9.3 3.9 2 1 0 3 3 3 2 Nucleoporin complex subunit 54 MAD PF05557.13 AAL64526.1 - 0.0026 16.2 31.6 0.0026 16.2 31.6 2.4 2 0 0 2 2 2 1 Mitotic checkpoint protein Snapin_Pallidin PF14712.6 AAL64526.1 - 0.0073 16.7 38.2 0.13 12.7 0.7 5.8 3 2 1 5 5 5 2 Snapin/Pallidin DUF641 PF04859.12 AAL64526.1 - 0.0092 16.3 10.4 0.0092 16.3 10.4 5.0 3 2 2 5 5 5 1 Plant protein of unknown function (DUF641) KxDL PF10241.9 AAL64526.1 - 0.0095 16.2 35.5 0.033 14.5 0.9 6.7 5 2 2 7 7 6 2 Uncharacterized conserved protein Sec34 PF04136.15 AAL64526.1 - 0.011 15.7 23.3 0.66 9.8 4.0 5.4 3 2 2 5 5 5 0 Sec34-like family PIF1 PF05970.14 AAL64526.1 - 0.012 14.8 0.7 5.6 6.0 0.0 3.3 3 0 0 3 3 3 0 PIF1-like helicase DUF3584 PF12128.8 AAL64526.1 - 0.014 13.0 42.6 0.098 10.2 20.4 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) SbcCD_C PF13558.6 AAL64526.1 - 0.016 15.4 0.0 0.062 13.5 0.0 2.0 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit MscS_porin PF12795.7 AAL64526.1 - 0.016 14.7 49.7 0.031 13.8 12.7 4.4 2 2 0 3 3 3 0 Mechanosensitive ion channel porin domain V_ATPase_I PF01496.19 AAL64526.1 - 0.019 12.9 28.1 0.54 8.1 8.9 3.2 2 1 1 3 3 3 0 V-type ATPase 116kDa subunit family AAA_5 PF07728.14 AAL64526.1 - 0.02 14.9 0.5 2.8 7.9 0.0 3.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Baculo_PEP_C PF04513.12 AAL64526.1 - 0.023 14.7 8.2 5 7.2 2.2 4.8 4 1 0 4 4 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus V-SNARE_C PF12352.8 AAL64526.1 - 0.026 14.8 4.7 3.8 7.9 0.1 3.9 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus DUF1664 PF07889.12 AAL64526.1 - 0.035 14.2 27.6 0.17 12.0 3.7 5.7 3 2 3 7 7 6 0 Protein of unknown function (DUF1664) EzrA PF06160.12 AAL64526.1 - 0.048 11.8 44.6 0.2 9.8 22.7 3.1 2 2 0 2 2 2 0 Septation ring formation regulator, EzrA Prefoldin_2 PF01920.20 AAL64526.1 - 0.085 12.8 52.4 0.38 10.7 2.3 6.6 4 2 1 6 6 6 0 Prefoldin subunit Laminin_II PF06009.12 AAL64526.1 - 0.1 12.6 33.9 1.2 9.2 2.1 5.6 2 2 3 5 5 5 0 Laminin Domain II MCPsignal PF00015.21 AAL64526.1 - 0.1 12.4 9.9 0.8 9.5 1.1 4.0 4 1 1 5 5 4 0 Methyl-accepting chemotaxis protein (MCP) signalling domain RNF220 PF15926.5 AAL64526.1 - 0.1 12.2 3.7 0.25 11.0 3.7 1.7 1 1 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 AAA_19 PF13245.6 AAL64526.1 - 0.12 12.7 0.3 2.3 8.5 0.3 2.7 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AAL64526.1 - 0.14 11.8 1.4 2.9 7.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 AAL64526.1 - 0.21 12.0 5.0 0.2 12.1 0.2 3.1 2 2 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) DUF948 PF06103.11 AAL64526.1 - 0.38 11.1 12.3 6.6 7.1 0.2 5.3 4 2 1 5 5 5 0 Bacterial protein of unknown function (DUF948) IFT57 PF10498.9 AAL64526.1 - 0.39 9.6 42.1 0.11 11.4 2.7 3.8 3 1 1 4 4 4 0 Intra-flagellar transport protein 57 Exonuc_VII_L PF02601.15 AAL64526.1 - 0.53 9.8 37.6 0.44 10.1 10.4 3.3 1 1 1 2 2 1 0 Exonuclease VII, large subunit Uso1_p115_C PF04871.13 AAL64526.1 - 0.59 10.5 51.4 0.5 10.8 10.8 4.8 1 1 4 5 5 5 0 Uso1 / p115 like vesicle tethering protein, C terminal region BLOC1_2 PF10046.9 AAL64526.1 - 0.68 10.3 40.8 7.1 7.0 4.4 7.3 4 2 3 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Syntaxin-6_N PF09177.11 AAL64526.1 - 0.82 10.3 39.3 0.51 10.9 3.7 5.8 1 1 4 5 5 5 0 Syntaxin 6, N-terminal MukB PF04310.12 AAL64526.1 - 0.88 9.3 0.0 0.88 9.3 0.0 3.0 3 1 2 5 5 3 0 MukB N-terminal FliD_C PF07195.12 AAL64526.1 - 1.7 8.0 12.4 10 5.5 3.3 4.2 2 2 1 3 3 3 0 Flagellar hook-associated protein 2 C-terminus DUF3287 PF11690.8 AAL64526.1 - 2.3 7.9 20.7 1 9.1 0.4 4.3 3 1 1 4 4 4 0 Protein of unknown function (DUF3287) AAA_30 PF13604.6 AAL64526.1 - 2.5 7.8 7.6 0.48 10.1 0.1 3.1 3 1 1 4 4 4 0 AAA domain Tropomyosin_1 PF12718.7 AAL64526.1 - 2.5 8.2 71.9 2.3 8.4 7.8 6.3 3 2 2 5 5 5 0 Tropomyosin like Vps51 PF08700.11 AAL64526.1 - 3.3 7.9 15.0 0.41 10.7 1.4 5.2 4 2 1 5 5 5 0 Vps51/Vps67 TACC_C PF05010.14 AAL64526.1 - 3.5 7.4 51.0 0.062 13.1 15.4 3.9 2 2 1 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF3829 PF12889.7 AAL64526.1 - 4.2 6.8 17.8 0.79 9.2 11.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3829) SesA PF17107.5 AAL64526.1 - 4.5 7.5 25.2 0.9 9.7 6.4 4.7 2 1 2 4 4 4 0 N-terminal domain on NACHT_NTPase and P-loop NTPases HMMR_N PF15905.5 AAL64526.1 - 4.7 6.6 53.8 0.28 10.6 28.5 2.8 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal LOH1CR12 PF10158.9 AAL64526.1 - 5.3 7.1 8.6 0.34 10.9 1.6 2.7 3 1 1 4 4 1 0 Tumour suppressor protein Fez1 PF06818.15 AAL64526.1 - 5.4 7.4 56.3 0.11 12.9 3.4 4.8 1 1 3 4 4 4 0 Fez1 HemX PF04375.14 AAL64526.1 - 6.5 5.9 28.5 0.91 8.8 2.3 4.1 3 1 1 4 4 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF3450 PF11932.8 AAL64526.1 - 6.9 5.9 47.2 0.26 10.5 4.3 5.2 2 2 3 5 5 5 0 Protein of unknown function (DUF3450) CorA PF01544.18 AAL64526.1 - 7.7 5.7 48.4 0.48 9.7 10.5 4.2 2 2 2 4 4 4 0 CorA-like Mg2+ transporter protein eRF1_2 PF03464.15 AAL64527.1 - 2.3e-34 118.6 0.0 4.4e-34 117.7 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 2 acVLRF1 PF18859.1 AAL64527.1 - 6.2e-14 52.4 0.0 1.5e-13 51.2 0.0 1.6 1 1 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 AAL64527.1 - 2.4e-13 50.5 0.0 4.7e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 eRF1_3 PF03465.15 AAL64527.1 - 4.3e-09 36.9 4.7 1.3e-08 35.3 2.8 2.7 2 1 0 2 2 2 1 eRF1 domain 3 eRF1_1 PF03463.15 AAL64527.1 - 7.1e-06 26.1 0.0 1.4e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 Ribosomal_L7Ae PF01248.26 AAL64527.1 - 7.8e-05 22.3 0.3 0.00019 21.1 0.3 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SpoU_sub_bind PF08032.12 AAL64527.1 - 0.043 14.1 1.2 0.14 12.5 0.2 2.3 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding FAM25 PF15825.5 AAL64527.1 - 0.97 9.8 7.1 4.3 7.8 2.6 2.8 2 0 0 2 2 2 0 FAM25 family Ribosomal_S10 PF00338.22 AAL64528.1 - 1.1e-24 86.5 0.0 1.2e-24 86.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e PriA_C PF18074.1 AAL64528.1 - 0.012 16.4 0.0 0.019 15.7 0.0 1.4 1 0 0 1 1 1 0 Primosomal protein N C-terminal domain SurE PF01975.17 AAL64529.1 - 1.8e-43 148.6 0.0 2.2e-43 148.3 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE HTH_24 PF13412.6 AAL64531.1 - 8.5e-08 31.6 0.0 1.3e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 AAL64531.1 - 1.1e-06 28.4 0.0 1.9e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 AAL64531.1 - 4.6e-06 26.6 0.0 6e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain DprA_WH PF17782.1 AAL64531.1 - 0.011 15.9 0.0 0.014 15.5 0.0 1.2 1 0 0 1 1 1 0 DprA winged helix domain HTH_12 PF08461.10 AAL64531.1 - 0.11 12.4 0.1 0.89 9.5 0.1 2.0 1 1 0 1 1 1 0 Ribonuclease R winged-helix domain TFIIE_alpha PF02002.17 AAL64531.1 - 0.13 12.1 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 TFIIE alpha subunit TYW3 PF02676.14 AAL64532.1 - 1.4e-27 96.5 0.0 4.1e-27 94.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase TYW3 DHDPS PF00701.22 AAL64533.1 - 4.8e-56 189.6 0.0 6e-56 189.3 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PT-VENN PF04829.13 AAL64533.1 - 0.29 11.2 1.5 0.35 11.0 0.4 1.7 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif PmbA_TldD PF01523.16 AAL64535.1 - 7.3e-48 163.8 0.3 1.5e-47 162.7 0.0 1.6 2 0 0 2 2 2 1 Putative modulator of DNA gyrase PmbA_TldD PF01523.16 AAL64536.1 - 4.5e-29 102.2 0.0 7.1e-29 101.5 0.0 1.3 1 0 0 1 1 1 1 Putative modulator of DNA gyrase NifW PF03206.14 AAL64537.1 - 0.11 13.0 0.0 0.12 12.9 0.0 1.1 1 0 0 1 1 1 0 Nitrogen fixation protein NifW DUF4663 PF15668.5 AAL64538.1 - 0.7 8.9 2.1 1.1 8.2 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) Ion_trans_2 PF07885.16 AAL64539.1 - 0.18 11.8 3.9 3.4 7.7 0.2 2.3 2 0 0 2 2 2 0 Ion channel MFS_1 PF07690.16 AAL64540.1 - 1.1e-47 162.7 75.7 4.8e-37 127.7 50.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 AAL64540.1 - 0.039 12.8 14.5 0.58 9.0 0.1 2.9 2 1 0 2 2 2 0 MFS_1 like family OATP PF03137.20 AAL64540.1 - 7.5 4.7 7.7 5 5.3 0.5 3.0 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Complex1_30kDa PF00329.19 AAL64541.1 - 2.3e-33 115.4 0.0 3.3e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit PAC2 PF09754.9 AAL64541.1 - 0.19 11.7 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 PAC2 family Oxidored_q6 PF01058.22 AAL64542.1 - 1.8e-23 82.8 0.3 2.4e-23 82.4 0.3 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Aldo_ket_red PF00248.21 AAL64543.1 - 1.6e-76 257.3 0.0 1.9e-76 257.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RHS PF03527.14 AAL64543.1 - 0.15 11.9 3.7 3.8 7.3 0.2 2.7 2 0 0 2 2 2 0 RHS protein ADH_N PF08240.12 AAL64544.1 - 5.8e-32 109.8 0.1 9.2e-32 109.2 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AAL64544.1 - 1.4e-28 99.5 0.0 2.1e-28 98.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 AAL64544.1 - 1.1e-05 24.9 0.4 1.8e-05 24.2 0.4 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Glu_dehyd_C PF16912.5 AAL64544.1 - 5.7e-05 22.7 0.1 8.5e-05 22.1 0.1 1.1 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus TrkA_N PF02254.18 AAL64544.1 - 0.013 15.8 0.1 0.02 15.1 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 AAL64544.1 - 0.018 14.4 0.1 0.031 13.6 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF4213 PF13938.6 AAL64544.1 - 0.12 12.6 0.5 0.33 11.2 0.5 1.7 1 0 0 1 1 1 0 Putative heavy-metal chelation SCP2 PF02036.17 AAL64545.1 - 4.5e-07 30.3 0.0 5.9e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 SCP-2 sterol transfer family SCP_3 PF17844.1 AAL64545.1 - 0.15 11.8 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial SCP ortholog RBFA PF02033.18 AAL64546.1 - 0.0025 18.2 0.1 0.0062 17.0 0.1 1.7 1 0 0 1 1 1 1 Ribosome-binding factor A TMEM135_C_rich PF15982.5 AAL64546.1 - 0.014 16.0 0.2 0.027 15.1 0.2 1.4 1 0 0 1 1 1 0 N-terminal cysteine-rich region of Transmembrane protein 135 THUMP PF02926.17 AAL64547.1 - 6.1e-18 65.3 1.0 8.4e-18 64.9 0.8 1.3 1 1 0 1 1 1 1 THUMP domain Abhydrolase_1 PF00561.20 AAL64548.1 - 1.8e-12 47.5 0.0 1.2e-07 31.6 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAL64548.1 - 8.8e-10 39.6 0.7 0.00038 21.1 0.5 2.0 1 1 1 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAL64548.1 - 0.17 11.1 0.0 0.28 10.4 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Pterin_bind PF00809.22 AAL64549.1 - 2.3e-50 171.6 0.0 3e-37 128.6 0.0 2.0 2 0 0 2 2 2 2 Pterin binding enzyme CdhD PF03599.16 AAL64549.1 - 0.035 12.8 0.0 0.052 12.3 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit Radical_SAM PF04055.21 AAL64551.1 - 1.7e-28 100.1 0.3 2.9e-28 99.3 0.1 1.5 2 0 0 2 2 2 1 Radical SAM superfamily UPF0004 PF00919.20 AAL64551.1 - 1.2e-14 54.2 0.0 2.2e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM_2 PF18693.1 AAL64551.1 - 8.7e-05 22.6 0.4 0.00055 20.0 0.4 2.3 1 1 0 1 1 1 1 TRAM domain TRAM PF01938.20 AAL64551.1 - 0.0009 19.2 0.4 0.0018 18.2 0.4 1.6 1 0 0 1 1 1 1 TRAM domain DUF1450 PF07293.11 AAL64551.1 - 0.019 14.8 0.2 0.063 13.1 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1450) tRNA-synt_1g PF09334.11 AAL64552.1 - 1.3e-155 518.0 0.0 1.6e-155 517.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 AAL64552.1 - 8e-12 44.2 0.1 9.3e-07 27.5 0.1 3.6 3 1 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 AAL64552.1 - 3.4e-07 30.3 0.6 6.6e-07 29.4 0.6 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 AAL64552.1 - 6.4e-05 22.4 0.0 0.0011 18.4 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain DZR PF12773.7 AAL64552.1 - 0.084 12.9 3.9 0.16 12.0 3.9 1.4 1 0 0 1 1 1 0 Double zinc ribbon IL34 PF15036.6 AAL64552.1 - 0.1 12.7 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Interleukin 34 Arg_decarbox_C PF17944.1 AAL64552.1 - 0.23 12.0 1.6 4.2 8.0 0.0 3.1 3 1 0 3 3 3 0 Arginine decarboxylase C-terminal helical extension zinc_ribbon_2 PF13240.6 AAL64552.1 - 0.49 10.2 10.1 4.1 7.3 1.6 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zf-RING_7 PF02591.15 AAL64552.1 - 3 8.1 8.5 2 8.7 0.6 3.5 3 0 0 3 3 3 0 C4-type zinc ribbon domain Zn-ribbon_8 PF09723.10 AAL64552.1 - 3.2 7.9 5.9 0.82 9.8 0.9 2.4 1 1 1 2 2 2 0 Zinc ribbon domain SNARE_assoc PF09335.11 AAL64553.1 - 8.6e-08 32.7 6.5 8.6e-08 32.7 6.5 2.3 2 1 1 3 3 3 1 SNARE associated Golgi protein DUF2062 PF09835.9 AAL64553.1 - 6.3 6.6 16.0 51 3.7 16.0 2.1 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) Prenyltransf PF01255.19 AAL64554.1 - 5e-65 219.2 0.0 5.6e-65 219.0 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Phytochelatin_C PF09328.10 AAL64554.1 - 0.17 11.2 0.1 0.24 10.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1984) tRNA_bind PF01588.20 AAL64555.1 - 1.4e-26 92.4 0.2 1.6e-26 92.2 0.2 1.1 1 0 0 1 1 1 1 Putative tRNA binding domain RuvA_N PF01330.21 AAL64556.1 - 0.0021 18.1 3.5 0.29 11.3 0.2 2.4 1 1 1 2 2 2 2 RuvA N terminal domain DUF3924 PF13062.6 AAL64556.1 - 0.017 15.1 0.1 0.043 13.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3924) SseC PF04888.12 AAL64556.1 - 0.44 10.1 1.6 0.51 9.9 1.6 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Big_3_5 PF16640.5 AAL64558.1 - 1.2e-17 63.8 12.9 0.0001 22.4 0.1 7.6 7 0 0 7 7 7 5 Bacterial Ig-like domain (group 3) TcfC PF16967.5 AAL64558.1 - 0.00085 18.8 0.0 8.2 6.0 0.0 4.3 4 0 0 4 4 4 2 E-set like domain CarboxypepD_reg PF13620.6 AAL64558.1 - 0.032 14.5 1.0 11 6.4 0.0 3.9 3 0 0 3 3 3 0 Carboxypeptidase regulatory-like domain HAD_2 PF13419.6 AAL64559.1 - 7.6e-08 32.6 0.0 1.1e-07 32.1 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAL64559.1 - 1.4e-05 25.5 0.6 0.00015 22.1 0.6 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AAL64559.1 - 0.00055 20.0 0.0 1.2 9.3 0.0 2.6 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase HAD PF12710.7 AAL64559.1 - 0.00087 19.7 0.0 0.0015 18.9 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AAL64559.1 - 0.0093 16.0 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like CbiA PF01656.23 AAL64560.1 - 0.00016 21.7 0.1 0.00076 19.5 0.1 2.0 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 AAL64560.1 - 0.00093 18.7 0.5 0.086 12.3 0.1 2.2 2 0 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase AAA_31 PF13614.6 AAL64560.1 - 0.0047 16.9 0.1 0.027 14.4 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 AAL64560.1 - 0.039 13.5 0.1 0.36 10.4 0.2 2.0 2 0 0 2 2 2 0 AAA domain IF3_N PF05198.16 AAL64560.1 - 0.11 12.8 0.1 0.2 12.0 0.1 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-3, N-terminal domain Phage_holin_3_6 PF07332.11 AAL64561.1 - 0.0038 17.3 0.0 0.0041 17.1 0.0 1.0 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III Wzz PF02706.15 AAL64561.1 - 0.045 14.1 0.1 0.048 14.0 0.1 1.1 1 0 0 1 1 1 0 Chain length determinant protein HTH_16 PF12645.7 AAL64562.1 - 0.042 13.9 0.0 0.36 10.9 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain Vault_4 PF17796.1 AAL64562.1 - 0.12 12.4 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Major Vault Protein repeat domain AAA_17 PF13207.6 AAL64563.1 - 0.036 14.5 0.0 0.075 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain SBP_bac_3 PF00497.20 AAL64564.1 - 8.5e-52 175.8 0.2 1e-51 175.6 0.2 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.7 AAL64564.1 - 1.7e-05 24.5 0.1 0.0002 21.0 0.1 2.1 2 0 0 2 2 2 1 ABC transporter, phosphonate, periplasmic substrate-binding protein Lig_chan-Glu_bd PF10613.9 AAL64564.1 - 5.3e-05 23.4 0.0 0.00023 21.3 0.0 1.9 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site NMT1 PF09084.11 AAL64564.1 - 0.0052 16.8 0.3 0.012 15.5 0.3 1.6 1 1 1 2 2 2 1 NMT1/THI5 like LysR_substrate PF03466.20 AAL64564.1 - 0.015 14.7 0.1 0.47 9.8 0.0 2.2 2 0 0 2 2 2 0 LysR substrate binding domain ATPase_gene1 PF09527.10 AAL64564.1 - 2.5 8.4 5.4 47 4.3 0.0 2.4 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter DUF192 PF02643.15 AAL64565.1 - 6.8e-12 45.4 0.0 1.2e-11 44.6 0.0 1.4 1 1 0 1 1 1 1 Uncharacterized ACR, COG1430 DUF4234 PF14018.6 AAL64566.1 - 0.0052 16.9 5.4 0.0052 16.9 5.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4234) DUF1700 PF08006.11 AAL64566.1 - 4.6 6.7 8.5 0.74 9.3 1.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) Stevor PF17410.2 AAL64566.1 - 5.1 6.6 7.6 0.61 9.6 2.6 1.8 1 1 1 2 2 2 0 Subtelomeric Variable Open Reading frame SIR2 PF02146.17 AAL64567.1 - 3.8e-52 176.8 0.0 4.6e-52 176.5 0.0 1.1 1 0 0 1 1 1 1 Sir2 family zinc_ribbon_4 PF13717.6 AAL64567.1 - 0.00027 20.8 0.7 0.00056 19.8 0.7 1.6 1 0 0 1 1 1 1 zinc-ribbon domain Zn-ribbon_8 PF09723.10 AAL64567.1 - 0.0046 17.0 0.2 0.0087 16.2 0.2 1.4 1 0 0 1 1 1 1 Zinc ribbon domain zf-ribbon_3 PF13248.6 AAL64567.1 - 0.013 14.9 3.8 0.22 11.0 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 AAL64567.1 - 0.022 14.8 0.2 0.044 13.8 0.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon TF_Zn_Ribbon PF08271.12 AAL64567.1 - 0.027 14.0 2.1 0.21 11.1 2.5 2.0 1 1 1 2 2 2 0 TFIIB zinc-binding zinc_ribbon_2 PF13240.6 AAL64567.1 - 0.031 14.0 3.0 2.6 7.9 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain HypA PF01155.19 AAL64567.1 - 0.043 13.8 0.2 0.089 12.8 0.2 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_15 PF17032.5 AAL64567.1 - 0.063 14.0 0.0 0.12 13.1 0.0 1.4 1 0 0 1 1 1 0 zinc-ribbon family DUF35_N PF12172.8 AAL64567.1 - 0.29 11.1 1.8 22 5.1 0.1 2.3 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Zn_ribbon_SprT PF17283.2 AAL64567.1 - 0.55 10.2 3.3 2.8 7.9 3.3 1.9 1 1 0 1 1 1 0 SprT-like zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 AAL64567.1 - 0.7 9.9 5.6 0.29 11.1 0.8 2.2 1 1 1 2 2 2 0 Transposase zinc-ribbon domain DUF309 PF03745.14 AAL64568.1 - 5.8e-17 61.1 0.1 8.7e-17 60.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF309) CBS PF00571.28 AAL64569.1 - 5.6e-30 103.6 6.6 1.2e-14 54.5 0.2 2.1 2 0 0 2 2 2 2 CBS domain PRC PF05239.16 AAL64569.1 - 0.012 15.7 5.0 0.089 12.9 0.1 2.8 1 1 1 2 2 2 0 PRC-barrel domain DUF3659 PF12396.8 AAL64569.1 - 0.017 15.0 0.2 5.4 7.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) Glyco_hydro_38 PF18438.1 AAL64569.1 - 0.023 14.8 0.0 3.7 7.6 0.0 2.1 2 0 0 2 2 2 0 Glycosyl hydrolases family 38 C-terminal domain 1 IF3_N PF05198.16 AAL64569.1 - 0.024 14.9 0.3 3.7 7.9 0.1 2.5 2 0 0 2 2 2 0 Translation initiation factor IF-3, N-terminal domain NTP_transferase PF00483.23 AAL64574.1 - 1.1e-33 116.8 0.0 1.4e-33 116.6 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AAL64574.1 - 5.3e-13 49.6 0.0 8.9e-13 48.9 0.0 1.4 1 1 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 AAL64574.1 - 0.00018 21.3 0.0 0.00027 20.7 0.0 1.5 1 1 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase tRNA-synt_1c PF00749.21 AAL64575.1 - 6.3e-75 252.0 0.0 8.3e-75 251.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 AAL64575.1 - 1.1e-24 87.2 0.0 2.2e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain DUF354 PF04007.12 AAL64576.1 - 3.6e-39 134.8 0.0 4.3e-39 134.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF354) DUF386 PF04074.12 AAL64576.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 YhcH/YjgK/YiaL AAA_18 PF13238.6 AAL64578.1 - 2.7e-12 47.4 0.0 7.2e-12 46.0 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.6 AAL64578.1 - 4.5e-06 27.1 0.1 3.9e-05 24.1 0.1 2.2 1 1 1 2 2 2 1 AAA domain NTPase_1 PF03266.15 AAL64578.1 - 0.00019 21.4 0.2 0.00035 20.5 0.2 1.6 1 1 0 1 1 1 1 NTPase ATP_bind_1 PF03029.17 AAL64578.1 - 0.00051 19.9 0.0 0.0007 19.5 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_28 PF13521.6 AAL64578.1 - 0.0017 18.7 0.9 0.0038 17.5 0.2 1.8 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 AAL64578.1 - 0.0023 18.4 0.1 0.0037 17.7 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AAL64578.1 - 0.0026 18.0 0.0 0.0049 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 AAL64578.1 - 0.0046 16.6 0.2 0.0079 15.8 0.2 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 AAL64578.1 - 0.0049 17.3 0.0 0.0081 16.6 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain ADK PF00406.22 AAL64578.1 - 0.0083 16.2 0.4 0.018 15.2 0.1 1.6 2 0 0 2 2 2 1 Adenylate kinase Thymidylate_kin PF02223.17 AAL64578.1 - 0.026 14.2 0.1 0.053 13.2 0.0 1.7 2 0 0 2 2 2 0 Thymidylate kinase Viral_helicase1 PF01443.18 AAL64578.1 - 0.043 13.5 0.0 0.1 12.3 0.0 1.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 AAL64578.1 - 0.044 13.5 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 AAL64578.1 - 0.057 12.4 0.1 0.092 11.7 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_5 PF07728.14 AAL64578.1 - 0.057 13.4 0.1 0.1 12.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Cytidylate_kin PF02224.18 AAL64578.1 - 0.091 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase AAA_3 PF07726.11 AAL64578.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 AAL64578.1 - 0.12 12.5 0.0 0.28 11.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 AAL64578.1 - 0.13 12.5 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AAL64578.1 - 0.17 11.6 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 AAL64578.1 - 0.19 11.6 0.1 3.7 7.5 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.22 AAL64578.1 - 0.21 12.0 0.0 0.31 11.5 0.0 1.3 1 0 0 1 1 1 0 RNA helicase KTI12 PF08433.10 AAL64578.1 - 0.25 10.8 0.0 0.35 10.3 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 tRNA-synt_2 PF00152.20 AAL64579.1 - 6.8e-90 301.3 0.0 8.1e-90 301.1 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 AAL64579.1 - 5.4e-13 48.7 0.0 1e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 AAL64579.1 - 0.0027 17.3 0.1 0.011 15.3 0.0 2.0 3 0 0 3 3 3 1 tRNA synthetases class II core domain (F) FGFR3_TM PF18123.1 AAL64579.1 - 0.08 12.5 0.4 0.16 11.5 0.4 1.5 1 0 0 1 1 1 0 Fibroblast growth factor receptor 3 transmembrane domain SIT PF15330.6 AAL64580.1 - 0.2 12.1 0.0 0.21 12.1 0.0 1.2 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT NAD_binding_2 PF03446.15 AAL64581.1 - 4.3e-21 75.7 0.0 1.2e-20 74.3 0.0 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 AAL64581.1 - 2.3e-12 47.2 1.0 4.8e-12 46.2 1.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 AAL64581.1 - 8.2e-05 22.0 0.0 0.00015 21.2 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 AAL64581.1 - 0.00024 21.0 0.0 0.00045 20.2 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 AAL64581.1 - 0.0019 18.8 0.0 0.0075 16.8 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 AAL64581.1 - 0.0022 18.0 0.0 0.004 17.2 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 AAL64581.1 - 0.0027 17.8 0.0 0.0098 16.0 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 AAL64581.1 - 0.015 15.0 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Sua5_yciO_yrdC PF01300.18 AAL64582.1 - 5.9e-53 179.0 0.0 8.1e-53 178.6 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 AAL64582.1 - 2.2e-26 93.0 0.0 3.2e-26 92.5 0.0 1.2 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding IN_DBD_C PF00552.21 AAL64582.1 - 0.017 14.4 0.1 0.036 13.4 0.1 1.5 1 0 0 1 1 1 0 Integrase DNA binding domain Methyltransf_25 PF13649.6 AAL64583.1 - 1.5e-09 38.4 0.0 2.7e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAL64583.1 - 1.4e-07 32.0 0.0 2.7e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAL64583.1 - 0.0005 19.9 0.0 0.00084 19.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 AAL64583.1 - 0.0022 17.3 0.0 0.0046 16.3 0.0 1.4 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 AAL64583.1 - 0.0026 17.6 0.0 0.007 16.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AAL64583.1 - 0.0027 17.1 0.0 0.0059 16.0 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 AAL64583.1 - 0.021 14.4 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PCMT PF01135.19 AAL64583.1 - 0.022 14.5 0.0 0.086 12.6 0.0 2.0 1 1 1 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_8 PF05148.15 AAL64583.1 - 0.067 13.0 0.0 5.1 6.9 0.0 2.1 2 0 0 2 2 2 0 Hypothetical methyltransferase FtsJ PF01728.19 AAL64583.1 - 0.08 13.0 0.0 0.61 10.2 0.0 2.0 2 0 0 2 2 2 0 FtsJ-like methyltransferase Pribosyltran_N PF13793.6 AAL64584.1 - 9.3e-22 77.2 0.0 4.8e-21 74.9 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 AAL64584.1 - 4.5e-17 62.0 0.1 3.3e-16 59.2 0.2 1.9 2 0 0 2 2 2 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.6 AAL64584.1 - 6.8e-09 36.0 0.1 3.4e-08 33.7 0.0 2.0 2 0 0 2 2 2 1 Phosphoribosyl synthetase-associated domain PRTase_2 PF15609.6 AAL64584.1 - 0.015 14.8 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase Hist_deacetyl PF00850.19 AAL64585.1 - 3.7e-69 233.5 0.0 4.7e-69 233.2 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Sod_Fe_N PF00081.22 AAL64585.1 - 0.083 13.4 0.0 0.19 12.2 0.0 1.6 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain Rep_1 PF01446.17 AAL64586.1 - 0.047 13.2 0.3 0.057 12.9 0.3 1.0 1 0 0 1 1 1 0 Replication protein Creatininase PF02633.14 AAL64587.1 - 4.4e-38 131.1 0.0 5.3e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 Creatinine amidohydrolase GCH_III PF05165.12 AAL64588.1 - 9.2e-33 113.5 0.0 8.9e-18 64.4 0.0 2.1 1 1 1 2 2 2 2 GTP cyclohydrolase III Csm1_B PF18211.1 AAL64588.1 - 0.05 13.4 0.0 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 Csm1 subunit domain B Guanylate_cyc PF00211.20 AAL64588.1 - 0.086 12.5 0.0 0.17 11.5 0.0 1.5 1 1 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain RibD_C PF01872.17 AAL64589.1 - 1.3e-48 165.5 0.0 1.4e-48 165.4 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain DHBP_synthase PF00926.19 AAL64590.1 - 2.9e-46 157.4 0.0 3.3e-46 157.2 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase CxxCxxCC PF03692.15 AAL64591.1 - 2.2e-17 63.5 3.0 2.2e-17 63.5 3.0 1.4 2 0 0 2 2 2 1 Putative zinc- or iron-chelating domain FAD_binding_3 PF01494.19 AAL64592.1 - 1.7e-17 63.7 2.0 2.2e-10 40.3 0.0 3.2 2 2 0 3 3 3 2 FAD binding domain FAD_oxidored PF12831.7 AAL64592.1 - 1.8e-06 27.6 0.1 1.8e-06 27.6 0.1 1.5 2 0 0 2 2 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 AAL64592.1 - 2.3e-05 23.8 0.1 3.2e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AAL64592.1 - 3.7e-05 23.0 1.4 5.2e-05 22.5 0.1 1.9 3 0 0 3 3 3 1 FAD binding domain GIDA PF01134.22 AAL64592.1 - 7.5e-05 22.0 0.0 0.00013 21.2 0.0 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 AAL64592.1 - 0.00014 21.2 0.0 0.00029 20.2 0.0 1.6 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 AAL64592.1 - 0.00034 19.6 0.0 0.035 12.9 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase HI0933_like PF03486.14 AAL64592.1 - 0.00043 19.1 0.1 0.00072 18.4 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 AAL64592.1 - 0.00074 19.2 2.3 0.0018 18.0 0.1 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AAL64592.1 - 0.00088 19.5 0.3 0.0054 16.9 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 AAL64592.1 - 0.0044 16.3 0.5 0.009 15.3 0.0 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 AAL64592.1 - 0.0051 16.1 0.2 0.0085 15.4 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAL64592.1 - 0.006 17.1 0.0 0.011 16.2 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase XdhC_C PF13478.6 AAL64592.1 - 0.0081 16.7 0.0 0.023 15.2 0.0 1.9 1 1 0 1 1 1 1 XdhC Rossmann domain Succ_CoA_lig PF13607.6 AAL64592.1 - 0.012 15.4 0.1 0.023 14.5 0.1 1.4 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain Lycopene_cycl PF05834.12 AAL64592.1 - 0.025 13.7 4.3 0.12 11.4 0.7 2.4 2 1 0 2 2 2 0 Lycopene cyclase protein QRPTase_C PF01729.19 AAL64593.1 - 3.8e-16 59.3 0.0 5.4e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain NAPRTase_N PF17767.1 AAL64593.1 - 4.9e-06 27.0 0.0 0.0065 16.9 0.0 2.4 1 1 1 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain QRPTase_N PF02749.16 AAL64593.1 - 5.2e-05 23.2 0.0 9.8e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain NAPRTase_C PF17956.1 AAL64593.1 - 0.0027 18.1 0.0 0.006 17.0 0.0 1.5 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase C-terminal domain Helicase_C_2 PF13307.6 AAL64594.1 - 1.6e-27 96.8 0.0 1.2e-26 93.9 0.0 2.1 1 1 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 AAL64594.1 - 9.8e-17 61.1 0.5 2.4e-16 59.9 0.5 1.7 1 1 0 1 1 1 1 DEAD_2 DEAD PF00270.29 AAL64594.1 - 6.4e-07 29.3 0.1 4.8e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 AAL64594.1 - 1.4e-05 25.2 0.0 0.0057 16.7 0.0 2.3 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit PhoH PF02562.16 AAL64594.1 - 0.0018 17.8 0.0 0.56 9.6 0.1 2.2 2 0 0 2 2 2 2 PhoH-like protein DUF2231 PF09990.9 AAL64595.1 - 0.095 13.1 5.8 0.13 12.7 5.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2231) DUF751 PF05421.11 AAL64595.1 - 0.29 11.9 3.0 0.48 11.2 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF751) Topoisom_bac PF01131.20 AAL64596.1 - 3.6e-105 352.3 0.0 4.6e-105 352.0 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 AAL64596.1 - 1.4e-19 70.2 0.1 7.8e-19 67.8 0.0 2.3 2 0 0 2 2 2 1 Toprim domain CdvA PF18822.1 AAL64596.1 - 0.0021 17.9 1.4 0.0051 16.6 1.4 1.7 1 0 0 1 1 1 1 CdvA-like coiled-coil domain Toprim_4 PF13662.6 AAL64596.1 - 0.0042 17.5 0.0 0.01 16.3 0.0 1.6 1 0 0 1 1 1 1 Toprim domain Toprim_2 PF13155.6 AAL64596.1 - 0.12 12.8 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 Toprim-like Diphthamide_syn PF01866.17 AAL64597.1 - 1e-17 64.6 0.0 8.8e-16 58.2 0.0 2.1 2 0 0 2 2 2 2 Putative diphthamide synthesis protein Glyco_transf_4 PF13439.6 AAL64597.1 - 0.06 13.3 0.1 0.31 11.0 0.0 2.0 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Cys_rich_CPXG PF14255.6 AAL64598.1 - 0.099 12.6 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 Cysteine-rich CPXCG Elf1 PF05129.13 AAL64598.1 - 0.11 12.5 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Rad50_zn_hook PF04423.14 AAL64598.1 - 0.19 11.6 0.3 0.41 10.5 0.2 1.6 2 0 0 2 2 2 0 Rad50 zinc hook motif DUF87 PF01935.17 AAL64599.1 - 3.4e-46 158.2 0.0 5.1e-46 157.6 0.0 1.2 1 0 0 1 1 1 1 Helicase HerA, central domain HAS-barrel PF09378.10 AAL64599.1 - 6.9e-12 45.3 1.4 3e-11 43.3 1.1 2.2 2 0 0 2 2 2 1 HAS barrel domain AAA_10 PF12846.7 AAL64599.1 - 1.3e-07 30.9 0.0 2.3e-05 23.5 0.0 2.2 2 0 0 2 2 2 2 AAA-like domain DUF853 PF05872.12 AAL64599.1 - 2e-05 23.4 0.0 0.023 13.3 0.0 2.1 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF853) Zot PF05707.12 AAL64599.1 - 0.0016 18.2 0.0 0.0051 16.5 0.0 1.8 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) TrwB_AAD_bind PF10412.9 AAL64599.1 - 0.0031 16.5 0.0 1.1 8.0 0.0 2.6 3 0 0 3 3 3 2 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 AAL64599.1 - 0.011 16.0 0.0 4.2 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 AAL64600.1 - 2e-50 171.0 0.0 3.2e-50 170.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 AAL64600.1 - 4.3e-38 130.1 0.1 3e-37 127.3 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 AAL64600.1 - 1.3e-17 63.9 5.8 3.8e-17 62.4 4.5 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 AAL64600.1 - 5.5e-07 29.4 2.5 1.6e-06 27.9 2.5 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 AAL64600.1 - 6.7e-06 26.2 0.0 4.3e-05 23.6 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AAL64600.1 - 0.00038 20.0 0.3 0.021 14.3 0.2 2.9 2 1 0 2 2 2 1 Ferrous iron transport protein B Septin PF00735.18 AAL64600.1 - 0.0015 17.9 0.0 0.0035 16.7 0.0 1.6 1 1 0 1 1 1 1 Septin Dynamin_N PF00350.23 AAL64600.1 - 0.013 15.6 0.1 2.3 8.2 0.0 2.4 1 1 1 2 2 2 0 Dynamin family Gtr1_RagA PF04670.12 AAL64600.1 - 0.033 13.6 0.0 0.068 12.5 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.10 AAL64600.1 - 0.12 11.8 0.0 3.5 7.0 0.0 2.4 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit Isochorismatase PF00857.20 AAL64601.1 - 3.6e-45 154.3 0.0 4.6e-45 153.9 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family PaRep2a PF07903.11 AAL64602.1 - 6e-08 32.6 0.0 7.1e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 PaRep2a protein Ribonuc_L-PSP PF01042.21 AAL64603.1 - 8.2e-45 151.7 0.0 9e-45 151.6 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP YtxH PF12732.7 AAL64603.1 - 0.083 13.4 0.0 0.12 13.0 0.0 1.2 1 0 0 1 1 1 0 YtxH-like protein PaRep2a PF07903.11 AAL64607.1 - 2.3e-60 201.8 0.4 2.6e-60 201.6 0.4 1.0 1 0 0 1 1 1 1 PaRep2a protein PaRep2b PF07775.11 AAL64608.1 - 2.8e-134 448.4 12.3 4.7e-91 305.8 1.6 2.0 1 1 1 2 2 2 2 PaRep2b protein DUF3016 PF11454.8 AAL64608.1 - 0.022 14.5 0.0 0.056 13.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3016) PmbA_TldD PF01523.16 AAL64608.1 - 0.034 14.0 0.1 0.05 13.4 0.1 1.2 1 0 0 1 1 1 0 Putative modulator of DNA gyrase TrmO PF01980.16 AAL64610.1 - 2.9e-28 98.5 0.0 3.5e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 tRNA-methyltransferase O HTH_45 PF14947.6 AAL64612.1 - 1.4e-06 28.2 0.0 1.8e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix DUF4364 PF14277.6 AAL64612.1 - 0.11 12.2 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) DUF3742 PF12553.8 AAL64613.1 - 0.48 10.5 4.8 3.5 7.8 2.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3742) DUF4990 PF16380.5 AAL64615.1 - 0.12 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function CN_hydrolase PF00795.22 AAL64617.1 - 2.8e-21 76.0 0.0 2e-20 73.2 0.0 1.9 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase NTP_transf_3 PF12804.7 AAL64618.1 - 3.8e-12 46.8 0.0 6.7e-12 46.1 0.0 1.5 1 1 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 AAL64618.1 - 3.2e-11 42.5 1.4 1.4e-06 27.8 0.4 4.9 2 1 4 6 6 6 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AAL64618.1 - 0.022 14.5 0.1 16 5.3 0.0 3.7 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase DUF1024 PF06260.12 AAL64618.1 - 0.037 14.3 0.2 0.091 13.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1024) SIS PF01380.22 AAL64619.1 - 1e-49 167.7 0.7 7.8e-28 96.9 0.5 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 AAL64619.1 - 1.7e-23 83.3 0.3 6e-23 81.5 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.6 AAL64619.1 - 2.8e-17 62.8 0.0 6.1e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain SIS_2 PF13580.6 AAL64619.1 - 6.3e-06 26.3 0.9 9.3e-05 22.5 0.1 2.8 3 0 0 3 3 3 1 SIS domain GATase_4 PF13230.6 AAL64619.1 - 0.0079 15.1 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Aconitase_2_N PF06434.13 AAL64619.1 - 0.046 13.4 0.1 0.087 12.4 0.1 1.4 1 0 0 1 1 1 0 Aconitate hydratase 2 N-terminus bact-PGI_C PF10432.9 AAL64619.1 - 0.13 12.3 0.5 0.47 10.5 0.1 2.3 2 1 0 2 2 2 0 Bacterial phospho-glucose isomerase C-terminal SIS domain T7SS_ESX_EspC PF10824.8 AAL64619.1 - 0.27 11.7 1.7 0.79 10.2 0.5 2.5 2 0 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm DHHA1 PF02272.19 AAL64620.1 - 2.4e-05 24.8 0.0 0.00012 22.5 0.0 2.1 2 0 0 2 2 2 1 DHHA1 domain STT3 PF02516.14 AAL64622.1 - 1.6e-16 60.3 35.2 2.9e-16 59.5 35.2 1.3 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit Nop10p PF04135.12 AAL64623.1 - 4.3e-23 81.1 0.8 5.5e-23 80.7 0.8 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Ribosomal_L32p PF01783.23 AAL64623.1 - 0.0061 16.8 1.3 0.01 16.0 1.3 1.4 1 0 0 1 1 1 1 Ribosomal L32p protein family Zn_ribbon_SprT PF17283.2 AAL64623.1 - 0.015 15.2 3.1 0.028 14.3 2.9 1.6 1 1 0 1 1 1 0 SprT-like zinc ribbon domain DUF1272 PF06906.11 AAL64623.1 - 0.052 13.6 1.9 0.07 13.2 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) RecO_C PF02565.15 AAL64623.1 - 0.059 13.2 0.0 0.066 13.0 0.0 1.0 1 0 0 1 1 1 0 Recombination protein O C terminal zf-ribbon_3 PF13248.6 AAL64623.1 - 0.064 12.7 5.9 0.77 9.2 5.9 2.2 1 1 0 1 1 1 0 zinc-ribbon domain zf-FPG_IleRS PF06827.14 AAL64623.1 - 0.086 12.7 3.6 0.35 10.8 0.6 2.2 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS PolC_DP2 PF03833.13 AAL64623.1 - 0.097 10.5 0.0 0.097 10.5 0.0 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DUF1258 PF06869.12 AAL64623.1 - 0.11 12.0 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) DUF35_N PF12172.8 AAL64623.1 - 0.12 12.3 4.5 0.11 12.3 3.3 1.6 1 1 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Zn-ribbon_8 PF09723.10 AAL64623.1 - 0.13 12.4 3.7 0.44 10.7 3.7 1.8 1 1 0 1 1 1 0 Zinc ribbon domain HypA PF01155.19 AAL64623.1 - 0.13 12.3 0.8 0.17 11.9 0.8 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ACC PF17848.1 AAL64623.1 - 0.19 11.9 3.3 3.9 7.6 0.3 2.2 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain zf-NADH-PPase PF09297.11 AAL64623.1 - 1.4 8.6 5.6 1.7 8.4 1.1 2.1 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain EIF_2_alpha PF07541.12 AAL64624.1 - 3.2e-22 78.8 0.1 8.1e-22 77.5 0.1 1.7 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 AAL64624.1 - 9.6e-06 25.9 0.5 3.5e-05 24.1 0.5 2.0 1 1 0 1 1 1 1 S1 RNA binding domain Ribosomal_S27e PF01667.17 AAL64625.1 - 1.3e-22 79.2 1.2 1.5e-22 79.0 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 AAL64625.1 - 0.00023 20.6 0.5 0.00031 20.2 0.5 1.2 1 0 0 1 1 1 1 TFIIB zinc-binding DUF35_N PF12172.8 AAL64625.1 - 0.0064 16.4 1.0 1.1 9.2 0.1 2.2 2 0 0 2 2 2 2 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF3797 PF12677.7 AAL64625.1 - 0.012 15.5 0.3 0.023 14.6 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3797) zf-ribbon_3 PF13248.6 AAL64625.1 - 0.022 14.2 0.4 0.2 11.1 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain Desulfoferrod_N PF06397.12 AAL64625.1 - 0.029 14.0 6.0 0.13 11.9 0.3 2.9 2 1 1 3 3 3 0 Desulfoferrodoxin, N-terminal domain zf-RING_10 PF16685.5 AAL64625.1 - 0.044 13.9 0.3 0.62 10.2 0.1 2.0 2 0 0 2 2 2 0 zinc RING finger of MSL2 Zn_Tnp_IS1595 PF12760.7 AAL64625.1 - 0.048 13.6 0.7 0.063 13.3 0.7 1.2 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DZR PF12773.7 AAL64625.1 - 0.056 13.5 0.5 0.11 12.6 0.5 1.4 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_6 PF14599.6 AAL64625.1 - 0.098 12.7 0.2 0.13 12.3 0.2 1.2 1 0 0 1 1 1 0 Zinc-ribbon zf-C2H2 PF00096.26 AAL64625.1 - 0.14 12.6 0.7 3 8.5 0.1 2.2 1 1 1 2 2 2 0 Zinc finger, C2H2 type TFIIS_C PF01096.18 AAL64625.1 - 0.17 11.8 1.7 2 8.4 1.7 2.1 1 1 0 1 1 1 0 Transcription factor S-II (TFIIS) Zn-ribbon_8 PF09723.10 AAL64625.1 - 0.23 11.6 2.2 2.4 8.4 0.5 2.1 1 1 1 2 2 2 0 Zinc ribbon domain CcmH PF03918.14 AAL64625.1 - 0.47 9.7 2.2 0.48 9.7 0.0 1.7 1 1 1 2 2 2 0 Cytochrome C biogenesis protein zinc_ribbon_5 PF13719.6 AAL64625.1 - 3.3 7.5 6.6 63 3.5 6.6 2.4 1 1 0 1 1 1 0 zinc-ribbon domain Ribosomal_L44 PF00935.19 AAL64626.1 - 5e-26 91.0 5.6 6.4e-26 90.6 5.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L44 zf-Mss51 PF13824.6 AAL64626.1 - 0.0028 17.7 1.5 1.9 8.6 0.3 2.1 1 1 0 2 2 2 2 Zinc-finger of mitochondrial splicing suppressor 51 zinc_ribbon_2 PF13240.6 AAL64626.1 - 0.0074 16.0 1.9 0.67 9.8 0.1 2.3 2 0 0 2 2 2 1 zinc-ribbon domain Rubredoxin_2 PF18073.1 AAL64626.1 - 0.0087 15.8 1.2 0.36 10.6 0.1 2.2 2 0 0 2 2 2 1 Rubredoxin metal binding domain DUF2225 PF09986.9 AAL64626.1 - 0.016 14.9 1.6 0.024 14.4 1.6 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) RNA_POL_M_15KD PF02150.16 AAL64626.1 - 0.021 14.7 1.1 0.21 11.5 0.1 2.2 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 AAL64626.1 - 0.03 14.3 0.3 6.8 6.8 0.0 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Zn_Tnp_IS1 PF03811.13 AAL64626.1 - 0.039 13.7 1.6 0.1 12.4 0.1 2.2 2 0 0 2 2 2 0 InsA N-terminal domain HNH_5 PF14279.6 AAL64626.1 - 0.042 13.7 0.7 0.96 9.4 0.1 2.2 2 0 0 2 2 2 0 HNH endonuclease zf-ribbon_3 PF13248.6 AAL64626.1 - 0.043 13.2 2.4 3.1 7.3 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-LITAF-like PF10601.9 AAL64626.1 - 0.047 14.0 1.1 0.62 10.4 0.1 2.1 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain zf_UBZ PF18439.1 AAL64626.1 - 0.049 13.2 1.6 4.4 7.0 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger TF_Zn_Ribbon PF08271.12 AAL64626.1 - 0.077 12.5 1.4 4.2 7.0 0.1 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding zinc_ribbon_4 PF13717.6 AAL64626.1 - 0.078 12.9 2.2 3.7 7.6 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain CpXC PF14353.6 AAL64626.1 - 0.086 12.9 0.2 5.1 7.2 0.0 2.1 2 0 0 2 2 2 0 CpXC protein HMA PF00403.26 AAL64626.1 - 0.14 12.6 2.0 0.82 10.2 0.2 2.3 2 1 0 2 2 2 0 Heavy-metal-associated domain IBR PF01485.21 AAL64626.1 - 0.16 12.2 2.9 0.3 11.3 2.9 1.4 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zf-DNL PF05180.12 AAL64626.1 - 0.18 11.8 2.4 2.4 8.2 0.1 2.2 2 0 0 2 2 2 0 DNL zinc finger DUF1660 PF07874.11 AAL64626.1 - 0.19 12.3 1.6 0.61 10.6 0.1 2.0 2 0 0 2 2 2 0 Prophage protein (DUF1660) zf-AN1 PF01428.16 AAL64626.1 - 0.19 11.9 3.8 0.81 9.9 0.3 2.2 2 0 0 2 2 2 0 AN1-like Zinc finger zf_C2H2_10 PF18414.1 AAL64626.1 - 0.49 10.0 2.9 5 6.8 0.2 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger zf-H2C2_2 PF13465.6 AAL64626.1 - 0.75 10.3 4.4 2.8 8.5 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger double domain TFIIS_C PF01096.18 AAL64626.1 - 1.4 8.8 6.1 2.5 8.0 0.6 2.5 2 1 0 2 2 2 0 Transcription factor S-II (TFIIS) DNA_primase_S PF01896.19 AAL64628.1 - 6e-28 98.1 0.0 9e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 DNA primase small subunit PCNA_N PF00705.18 AAL64629.1 - 1.3e-13 50.7 0.1 1.2e-12 47.6 0.0 2.0 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 AAL64629.1 - 8.7e-13 48.6 1.3 2.4e-12 47.2 0.6 1.8 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.16 AAL64629.1 - 1.3e-05 24.5 1.0 0.00022 20.4 0.3 2.2 1 1 0 2 2 2 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 AAL64629.1 - 3.7e-05 23.3 0.1 7.8e-05 22.2 0.1 1.5 1 1 0 1 1 1 1 Rad9 DUF3236 PF11576.8 AAL64629.1 - 0.064 13.0 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3236) DNA_pol3_beta PF00712.19 AAL64629.1 - 0.12 12.5 2.1 3.8 7.7 0.3 2.4 2 1 0 2 2 2 0 DNA polymerase III beta subunit, N-terminal domain XLF PF09302.11 AAL64629.1 - 0.16 12.1 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component TFIIS_C PF01096.18 AAL64630.1 - 2.5e-21 75.2 7.5 8.6e-20 70.3 4.1 2.3 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 AAL64630.1 - 1e-08 34.9 7.8 2.4e-07 30.5 0.1 3.2 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 AAL64630.1 - 3.6e-06 26.9 5.0 0.0029 17.5 2.9 2.4 2 0 0 2 2 2 2 Transposase zinc-ribbon domain Lar_restr_allev PF14354.6 AAL64630.1 - 5.3e-05 23.5 2.8 0.06 13.7 1.3 2.2 2 0 0 2 2 2 2 Restriction alleviation protein Lar DZR PF12773.7 AAL64630.1 - 0.00018 21.4 4.8 0.22 11.5 0.1 2.6 2 1 0 2 2 2 2 Double zinc ribbon TF_Zn_Ribbon PF08271.12 AAL64630.1 - 0.00028 20.3 6.5 0.0079 15.7 0.3 2.7 2 2 0 2 2 2 1 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 AAL64630.1 - 0.00034 20.7 6.5 3.2 8.0 0.1 3.3 3 0 0 3 3 3 2 Zinc ribbon domain PhnA_Zn_Ribbon PF08274.12 AAL64630.1 - 0.00097 19.0 0.7 1.8 8.6 0.1 2.9 2 1 0 2 2 2 2 PhnA Zinc-Ribbon UPF0547 PF10571.9 AAL64630.1 - 0.0011 19.0 10.8 1.5 9.0 0.1 4.0 4 0 0 4 4 4 2 Uncharacterised protein family UPF0547 zinc_ribbon_2 PF13240.6 AAL64630.1 - 0.0013 18.4 14.7 0.72 9.7 0.2 4.1 4 0 0 4 4 4 2 zinc-ribbon domain zf-TFIIB PF13453.6 AAL64630.1 - 0.0015 17.8 10.3 0.0061 15.9 0.4 2.9 2 1 0 2 2 2 1 Transcription factor zinc-finger Zn_Tnp_IS91 PF14319.6 AAL64630.1 - 0.0016 18.5 6.0 0.083 12.9 0.6 3.0 1 1 2 3 3 3 1 Transposase zinc-binding domain zinc_ribbon_4 PF13717.6 AAL64630.1 - 0.0016 18.3 9.6 0.72 9.8 0.5 3.3 3 0 0 3 3 3 2 zinc-ribbon domain zinc_ribbon_13 PF09855.9 AAL64630.1 - 0.0018 18.4 5.6 4.2 7.6 0.0 3.2 3 0 0 3 3 3 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) Elf1 PF05129.13 AAL64630.1 - 0.0021 18.0 2.0 1.4 9.0 0.2 2.4 1 1 0 2 2 2 2 Transcription elongation factor Elf1 like CpXC PF14353.6 AAL64630.1 - 0.0021 18.1 4.4 0.079 13.0 0.0 3.0 2 1 0 2 2 2 1 CpXC protein OrfB_Zn_ribbon PF07282.11 AAL64630.1 - 0.0022 17.8 5.9 0.13 12.2 1.6 2.5 2 1 0 2 2 2 2 Putative transposase DNA-binding domain Baculo_LEF5_C PF11792.8 AAL64630.1 - 0.006 16.2 3.1 0.009 15.7 0.2 2.4 2 1 1 3 3 3 1 Baculoviridae late expression factor 5 C-terminal domain DUF2387 PF09526.10 AAL64630.1 - 0.006 16.7 6.4 0.86 9.8 1.3 2.4 1 1 1 2 2 2 2 Probable metal-binding protein (DUF2387) HypA PF01155.19 AAL64630.1 - 0.01 15.9 2.3 0.09 12.8 0.2 2.2 1 1 1 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ZPR1 PF03367.13 AAL64630.1 - 0.047 13.5 0.3 6.4 6.6 0.1 2.2 2 0 0 2 2 2 0 ZPR1 zinc-finger domain zf-Mss51 PF13824.6 AAL64630.1 - 0.06 13.5 5.4 3.8 7.7 2.3 2.5 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Zn_ribbon_SprT PF17283.2 AAL64630.1 - 0.093 12.7 6.1 3 7.8 0.4 3.1 3 0 0 3 3 3 0 SprT-like zinc ribbon domain DUF1936 PF09151.10 AAL64630.1 - 0.1 12.5 9.0 0.56 10.2 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1936) zinc_ribbon_15 PF17032.5 AAL64630.1 - 0.11 13.3 4.0 2.2 9.1 4.0 2.4 1 1 0 1 1 1 0 zinc-ribbon family zf_C2H2_10 PF18414.1 AAL64630.1 - 0.12 11.9 9.3 2.4 7.8 0.5 3.3 3 0 0 3 3 3 0 C2H2 type zinc-finger zf-NADH-PPase PF09297.11 AAL64630.1 - 0.14 11.9 8.4 4.8 6.9 0.1 3.9 4 0 0 4 4 4 0 NADH pyrophosphatase zinc ribbon domain A2L_zn_ribbon PF08792.10 AAL64630.1 - 0.17 11.6 5.4 6.1 6.7 0.1 3.4 3 0 0 3 3 3 0 A2L zinc ribbon domain zf-ribbon_3 PF13248.6 AAL64630.1 - 0.3 10.6 15.1 2.3 7.8 0.5 4.1 4 0 0 4 4 4 0 zinc-ribbon domain zf-tcix PF14952.6 AAL64630.1 - 0.39 10.4 10.0 6.6 6.4 0.2 3.4 3 0 0 3 3 3 0 Putative treble-clef, zinc-finger, Zn-binding DNA_RNApol_7kD PF03604.13 AAL64630.1 - 0.54 10.0 11.4 2.1 8.1 0.2 3.3 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit DUF35_N PF12172.8 AAL64630.1 - 0.81 9.6 11.0 7.2 6.6 0.2 3.5 4 0 0 4 4 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zinc_ribbon_10 PF10058.9 AAL64630.1 - 0.87 9.4 5.9 49 3.7 0.0 3.0 2 1 1 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein DUF4379 PF14311.6 AAL64630.1 - 0.9 10.0 11.9 7.2 7.1 0.5 3.2 2 1 1 3 3 3 0 Probable Zinc-ribbon domain Rubredoxin_2 PF18073.1 AAL64630.1 - 1 9.2 13.0 1.8 8.4 1.8 3.3 3 0 0 3 3 3 0 Rubredoxin metal binding domain DUF2072 PF09845.9 AAL64630.1 - 1.1 9.5 7.0 1.8 8.8 0.5 2.8 1 1 2 3 3 3 0 Zn-ribbon containing protein zf-ISL3 PF14690.6 AAL64630.1 - 1.2 9.9 10.7 7.1 7.4 0.5 3.7 3 1 1 4 4 4 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-H2C2_2 PF13465.6 AAL64630.1 - 2.1 8.9 10.8 5.9 7.5 0.5 3.3 3 0 0 3 3 3 0 Zinc-finger double domain Opy2 PF09463.10 AAL64630.1 - 2.3 8.6 8.1 7.8 6.9 0.1 3.2 4 0 0 4 4 3 0 Opy2 protein Rubredoxin PF00301.20 AAL64630.1 - 2.7 8.1 9.8 31 4.7 1.8 3.3 3 0 0 3 3 3 0 Rubredoxin zinc_ribbon_5 PF13719.6 AAL64630.1 - 2.7 7.8 5.8 36 4.2 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Nudix_N_2 PF14803.6 AAL64630.1 - 3.1 7.8 13.3 2.2 8.3 3.2 3.4 2 2 0 2 2 2 0 Nudix N-terminal Ogr_Delta PF04606.12 AAL64630.1 - 3.5 7.7 12.3 1.3 9.0 2.5 3.1 2 2 0 2 2 2 0 Ogr/Delta-like zinc finger Ribosomal_S19e PF01090.19 AAL64631.1 - 3.6e-52 175.7 0.0 4.1e-52 175.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e RuvB_C PF05491.13 AAL64631.1 - 0.0074 16.1 0.0 0.069 13.0 0.0 2.2 2 0 0 2 2 2 1 RuvB C-terminal winged helix domain HTH_45 PF14947.6 AAL64631.1 - 0.022 14.7 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix HemN_C PF06969.16 AAL64631.1 - 0.091 12.8 0.1 0.18 11.9 0.0 1.5 2 0 0 2 2 2 0 HemN C-terminal domain dsDNA_bind PF01984.20 AAL64632.1 - 2.5e-22 79.3 9.4 4.1e-22 78.5 9.4 1.2 1 0 0 1 1 1 1 Double-stranded DNA-binding domain SDA1 PF05285.12 AAL64632.1 - 0.00085 18.8 1.7 0.00096 18.7 1.7 1.1 1 0 0 1 1 1 1 SDA1 DUF4332 PF14229.6 AAL64632.1 - 0.016 15.4 1.9 0.023 15.0 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) FHIPEP PF00771.20 AAL64632.1 - 0.042 12.3 3.1 0.048 12.1 3.1 1.0 1 0 0 1 1 1 0 FHIPEP family Phage_Arf PF17585.2 AAL64632.1 - 0.078 12.9 0.2 0.078 12.9 0.2 1.9 2 0 0 2 2 2 0 Accessory recombination function protein DUF5401 PF17380.2 AAL64632.1 - 0.57 8.2 9.5 0.53 8.3 9.0 1.2 1 1 0 1 1 1 0 Family of unknown function (DUF5401) PcrB PF01884.17 AAL64634.1 - 4e-50 170.4 0.0 4.7e-50 170.2 0.0 1.0 1 0 0 1 1 1 1 PcrB family B12-binding PF02310.19 AAL64634.1 - 0.00088 19.3 0.4 1.1 9.4 0.0 3.1 2 1 1 3 3 3 2 B12 binding domain His_biosynth PF00977.21 AAL64634.1 - 0.0021 17.5 0.1 0.0044 16.5 0.0 1.5 2 0 0 2 2 2 1 Histidine biosynthesis protein TMP-TENI PF02581.17 AAL64634.1 - 0.025 13.9 0.1 0.065 12.6 0.1 1.7 1 0 0 1 1 1 0 Thiamine monophosphate synthase FIST PF08495.10 AAL64634.1 - 0.062 13.3 0.2 0.15 12.1 0.0 1.7 2 1 0 2 2 2 0 FIST N domain LSDAT_prok PF18171.1 AAL64634.1 - 0.1 11.8 0.0 0.38 10.0 0.0 1.8 2 0 0 2 2 2 0 SLOG in TRPM, prokaryote IMPDH PF00478.25 AAL64634.1 - 0.11 11.4 0.0 1.7 7.6 0.0 2.0 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Epimerase_2 PF02350.19 AAL64634.1 - 0.16 10.8 0.1 0.75 8.6 0.1 2.1 2 0 0 2 2 2 0 UDP-N-acetylglucosamine 2-epimerase Elf1 PF05129.13 AAL64635.1 - 4.6e-16 58.6 0.0 5.7e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Lar_restr_allev PF14354.6 AAL64635.1 - 3.1e-05 24.3 0.3 4.7e-05 23.7 0.3 1.3 1 0 0 1 1 1 1 Restriction alleviation protein Lar Desulfoferrod_N PF06397.12 AAL64635.1 - 0.00099 18.7 2.3 0.0015 18.1 2.3 1.3 1 0 0 1 1 1 1 Desulfoferrodoxin, N-terminal domain TF_Zn_Ribbon PF08271.12 AAL64635.1 - 0.0022 17.5 1.4 0.0036 16.8 1.4 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding zinc_ribbon_4 PF13717.6 AAL64635.1 - 0.0022 17.8 0.1 2.9 7.9 0.1 2.3 2 0 0 2 2 2 2 zinc-ribbon domain zf-ribbon_3 PF13248.6 AAL64635.1 - 0.0025 17.2 2.6 0.11 11.9 0.1 2.3 2 0 0 2 2 2 1 zinc-ribbon domain zf-RING_7 PF02591.15 AAL64635.1 - 0.003 17.7 0.3 0.13 12.5 0.0 2.2 2 0 0 2 2 2 1 C4-type zinc ribbon domain Zn_ribbon_recom PF13408.6 AAL64635.1 - 0.011 16.2 3.5 1.1 9.8 3.5 2.4 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain Rubredoxin PF00301.20 AAL64635.1 - 0.014 15.4 1.0 0.24 11.5 0.1 2.3 2 0 0 2 2 2 0 Rubredoxin DZR PF12773.7 AAL64635.1 - 0.014 15.4 0.2 0.021 14.8 0.2 1.3 1 0 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 AAL64635.1 - 0.019 15.1 0.4 1.3 9.2 0.0 2.3 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_10 PF10058.9 AAL64635.1 - 0.034 13.9 1.4 4.1 7.2 0.2 2.2 1 1 1 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-ISL3 PF14690.6 AAL64635.1 - 0.036 14.7 0.7 0.37 11.5 0.1 2.4 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn_Tnp_IS1595 PF12760.7 AAL64635.1 - 0.036 14.0 2.5 0.38 10.8 2.5 2.1 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zf-C4_Topoisom PF01396.19 AAL64635.1 - 0.045 13.5 2.3 0.11 12.3 2.4 1.6 1 1 1 2 2 2 0 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_2 PF13240.6 AAL64635.1 - 0.045 13.5 4.9 0.42 10.4 4.9 2.1 1 1 0 1 1 1 0 zinc-ribbon domain zf-HYPF PF07503.12 AAL64635.1 - 0.049 13.4 1.1 4 7.3 0.1 2.3 2 0 0 2 2 2 0 HypF finger Zn_ribbon_SprT PF17283.2 AAL64635.1 - 0.055 13.4 1.2 0.055 13.4 1.2 1.8 2 1 0 2 2 2 0 SprT-like zinc ribbon domain RNA_POL_M_15KD PF02150.16 AAL64635.1 - 0.078 12.9 0.2 0.15 11.9 0.2 1.5 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit OrfB_Zn_ribbon PF07282.11 AAL64635.1 - 0.11 12.4 0.3 0.19 11.7 0.3 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-NADH-PPase PF09297.11 AAL64635.1 - 0.11 12.1 1.6 1 9.1 1.3 2.2 1 1 1 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Ribosomal_L32p PF01783.23 AAL64635.1 - 0.15 12.3 4.3 1.8 8.9 4.3 2.1 1 1 0 1 1 1 0 Ribosomal L32p protein family DUF678 PF05077.12 AAL64635.1 - 0.2 11.8 1.3 0.32 11.2 1.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF678) zf-RRN7 PF11781.8 AAL64635.1 - 0.27 11.0 4.2 8 6.2 0.4 2.3 1 1 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 MoeA_N PF03453.17 AAL64636.1 - 2.4e-30 105.4 1.1 3.9e-30 104.7 1.1 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 AAL64636.1 - 5e-10 39.2 0.2 2.4e-09 37.0 0.1 2.1 2 1 0 2 2 2 1 Probable molybdopterin binding domain Pribosyltran PF00156.27 AAL64637.1 - 4.1e-18 65.4 0.1 5.8e-18 64.9 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 AAL64637.1 - 0.032 13.7 0.0 0.041 13.3 0.0 1.1 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase SWIM PF04434.17 AAL64639.1 - 0.0012 18.4 0.1 0.002 17.8 0.1 1.3 1 0 0 1 1 1 1 SWIM zinc finger Inositol_P PF00459.25 AAL64640.1 - 2.5e-20 73.1 0.0 3.2e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.20 AAL64640.1 - 7e-05 22.4 0.0 0.00014 21.4 0.0 1.5 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain ATPase PF06745.13 AAL64641.1 - 2.3e-07 30.4 0.0 0.017 14.5 0.0 2.7 1 1 1 2 2 2 2 KaiC AAA_24 PF13479.6 AAL64641.1 - 7.6e-07 29.0 0.0 1.8e-05 24.6 0.0 2.6 3 1 0 3 3 3 1 AAA domain AAA_22 PF13401.6 AAL64641.1 - 2.8e-06 27.6 0.0 5e-05 23.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 AAL64641.1 - 5.5e-06 26.1 0.1 2.2e-05 24.1 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 AAL64641.1 - 2.3e-05 24.9 0.0 4.1e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AAL64641.1 - 0.00019 21.8 0.0 0.00037 20.9 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 AAL64641.1 - 0.0044 17.0 0.0 0.032 14.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) GvpD PF07088.11 AAL64641.1 - 0.0052 15.5 0.0 1.1 7.8 0.0 2.2 1 1 1 2 2 2 2 GvpD gas vesicle protein AAA_18 PF13238.6 AAL64641.1 - 0.0061 17.1 0.0 0.032 14.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 AAL64641.1 - 0.009 16.4 0.0 0.017 15.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase NACHT PF05729.12 AAL64641.1 - 0.011 15.6 0.0 0.035 14.0 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_11 PF13086.6 AAL64641.1 - 0.02 14.7 0.0 0.039 13.7 0.0 1.4 2 0 0 2 2 1 0 AAA domain ATPase_2 PF01637.18 AAL64641.1 - 0.027 14.4 0.0 0.18 11.7 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_17 PF13207.6 AAL64641.1 - 0.04 14.3 0.0 0.11 13.0 0.0 1.7 2 0 0 2 2 1 0 AAA domain NTPase_1 PF03266.15 AAL64641.1 - 0.051 13.5 0.0 1.5 8.7 0.0 2.3 1 1 1 2 2 2 0 NTPase RuvB_N PF05496.12 AAL64641.1 - 0.056 13.2 0.1 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Bac_DnaA PF00308.18 AAL64641.1 - 0.059 13.2 0.0 0.19 11.5 0.0 1.8 1 1 0 1 1 1 0 Bacterial dnaA protein CobU PF02283.16 AAL64641.1 - 0.081 12.5 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_33 PF13671.6 AAL64641.1 - 0.1 12.7 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AAL64641.1 - 0.11 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 AAL64641.1 - 0.12 12.7 0.2 0.23 11.8 0.2 1.6 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.10 AAL64641.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF2075 PF09848.9 AAL64641.1 - 0.14 11.4 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 AAL64641.1 - 0.17 11.2 0.0 0.33 10.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.6 AAL64641.1 - 0.19 12.2 0.0 0.31 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain TRAM PF01938.20 AAL64642.1 - 2.6e-14 53.0 3.3 3e-14 52.7 3.3 1.1 1 0 0 1 1 1 1 TRAM domain CSD2 PF17876.1 AAL64642.1 - 0.0022 18.1 3.2 0.81 9.9 0.4 2.1 1 1 1 2 2 2 2 Cold shock domain CusF_Ec PF11604.8 AAL64642.1 - 0.0027 17.6 0.0 0.49 10.4 0.0 2.1 2 0 0 2 2 2 2 Copper binding periplasmic protein CusF OB_RNB PF08206.11 AAL64642.1 - 0.11 12.1 1.2 0.46 10.2 0.5 2.1 2 0 0 2 2 2 0 Ribonuclease B OB domain RseC_MucC PF04246.12 AAL64642.1 - 0.16 11.9 0.2 16 5.4 0.0 2.1 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC HTH_20 PF12840.7 AAL64643.1 - 0.0001 22.3 0.0 0.00022 21.2 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain UPF0154 PF03672.13 AAL64643.1 - 0.0018 18.3 0.0 0.0027 17.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0154) CitMHS PF03600.16 AAL64645.1 - 2.6e-26 92.5 16.3 2.7e-26 92.5 15.4 1.4 1 1 0 1 1 1 1 Citrate transporter TrkA_C PF02080.21 AAL64645.1 - 1e-05 25.2 0.1 2.4e-05 24.1 0.1 1.7 1 0 0 1 1 1 1 TrkA-C domain PsbM PF05151.12 AAL64645.1 - 0.12 12.2 6.0 7.1 6.5 1.9 3.9 2 0 0 2 2 2 0 Photosystem II reaction centre M protein (PsbM) ABC2_membrane PF01061.24 AAL64646.1 - 1.2e-08 34.6 20.7 1.2e-08 34.6 20.7 1.6 1 1 1 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 AAL64646.1 - 2.1e-05 23.8 18.5 2.1e-05 23.8 18.5 1.9 1 1 1 2 2 2 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 AAL64647.1 - 6.3e-10 38.8 19.2 6.3e-10 38.8 19.2 1.5 1 1 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 AAL64647.1 - 0.034 13.2 26.5 0.047 12.8 26.5 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein TcdA_TcdB_pore PF12920.7 AAL64647.1 - 3.2 5.9 6.1 4.4 5.4 6.1 1.1 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain ABC_tran PF00005.27 AAL64648.1 - 1.6e-24 87.0 0.0 2.1e-24 86.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAL64648.1 - 1.8e-12 47.7 0.0 1.3e-06 28.4 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AAL64648.1 - 0.00017 21.3 0.0 0.0003 20.5 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain Rad17 PF03215.15 AAL64648.1 - 0.012 15.5 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_15 PF13175.6 AAL64648.1 - 0.013 15.2 0.0 0.031 14.0 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 AAL64648.1 - 0.016 15.7 0.0 0.027 15.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 AAL64648.1 - 0.046 13.4 0.0 0.074 12.7 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 AAL64648.1 - 0.048 14.0 0.0 0.068 13.5 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain MukB PF04310.12 AAL64648.1 - 0.051 13.4 0.1 0.098 12.4 0.1 1.5 1 1 0 1 1 1 0 MukB N-terminal TsaE PF02367.17 AAL64648.1 - 0.16 12.0 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 AAL64648.1 - 0.18 12.0 0.1 0.49 10.5 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AAL64648.1 - 0.18 11.5 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AAL64648.1 - 0.19 11.4 0.0 0.43 10.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.6 AAL64648.1 - 0.24 10.0 0.0 0.32 9.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain HAD_2 PF13419.6 AAL64649.1 - 1.2e-31 110.1 0.0 1.5e-31 109.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAL64649.1 - 4.9e-15 56.4 0.2 1.9e-12 47.9 0.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AAL64649.1 - 1.7e-09 38.4 0.0 5.6e-09 36.7 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AAL64649.1 - 3.5e-06 27.0 0.0 6.6e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_3 PF08282.12 AAL64649.1 - 0.00035 20.4 0.0 0.18 11.5 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.13 AAL64649.1 - 0.0011 18.6 0.0 0.026 14.1 0.0 2.2 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase PaRep2b PF07775.11 AAL64650.1 - 3.2e-21 75.4 0.2 3.5e-21 75.3 0.2 1.0 1 0 0 1 1 1 1 PaRep2b protein ATPase_2 PF01637.18 AAL64652.1 - 2.8e-62 210.7 0.0 3.6e-62 210.3 0.0 1.1 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 AAL64652.1 - 3.6e-05 24.2 1.6 9.6e-05 22.8 0.3 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 AAL64652.1 - 0.00012 22.4 0.0 0.00037 20.8 0.0 1.7 1 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 AAL64652.1 - 0.00067 19.8 0.0 0.0023 18.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 AAL64652.1 - 0.0008 19.2 0.0 0.0018 18.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 AAL64652.1 - 0.0012 18.1 0.0 0.0018 17.5 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain Rad17 PF03215.15 AAL64652.1 - 0.0053 16.7 0.0 0.0083 16.1 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_14 PF13173.6 AAL64652.1 - 0.0056 16.7 0.0 0.0086 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 AAL64652.1 - 0.007 16.2 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein KAP_NTPase PF07693.14 AAL64652.1 - 0.0099 15.2 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain RNA_helicase PF00910.22 AAL64652.1 - 0.011 16.2 0.0 0.018 15.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 AAL64652.1 - 0.02 14.6 0.0 0.047 13.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 AAL64652.1 - 0.023 15.1 0.0 0.072 13.5 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 AAL64652.1 - 0.096 12.3 0.1 8.9 5.9 0.0 2.1 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain Adeno_IVa2 PF02456.15 AAL64652.1 - 0.14 11.0 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein DAP3 PF10236.9 AAL64652.1 - 0.19 10.8 0.0 0.33 10.1 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 DUF72 PF01904.18 AAL64654.1 - 3.3e-33 115.6 0.2 3.9e-33 115.4 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF72 DUF3275 PF11679.8 AAL64656.1 - 0.099 12.6 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) Asparaginase_2 PF01112.18 AAL64657.1 - 7.1e-80 268.3 6.1 8.3e-80 268.1 6.1 1.0 1 0 0 1 1 1 1 Asparaginase LPD30 PF18850.1 AAL64657.1 - 0.063 13.0 0.3 0.32 10.8 0.1 2.3 1 1 1 2 2 2 0 Large polyvalent protein associated domain 30 S4 PF01479.25 AAL64658.1 - 7.7e-17 60.7 0.1 1.7e-16 59.6 0.1 1.6 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 AAL64658.1 - 0.015 16.2 0.6 0.021 15.7 0.5 1.4 1 1 0 1 1 1 0 Ribosomal protein S4/S9 N-terminal domain TyrRSs_C PF16714.5 AAL64658.1 - 0.033 14.0 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 Tyrosyl-tRNA synthetase C-terminal domain Ribosomal_S13 PF00416.22 AAL64659.1 - 6.7e-36 123.5 0.0 7.9e-36 123.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 AAL64659.1 - 0.095 11.4 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) BPD_transp_1 PF00528.22 AAL64660.1 - 1.2e-25 90.4 15.4 1.2e-25 90.4 15.4 2.3 3 0 0 3 3 3 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 AAL64660.1 - 0.17 11.9 0.1 0.17 11.9 0.1 3.3 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C NADH_B2 PF14813.6 AAL64660.1 - 1.3 8.8 5.2 18 5.2 0.2 2.7 2 0 0 2 2 2 0 NADH dehydrogenase 1 beta subcomplex subunit 2 BPD_transp_1 PF00528.22 AAL64661.1 - 3.3e-33 115.0 15.0 3.3e-33 115.0 15.0 2.6 3 0 0 3 3 3 1 Binding-protein-dependent transport system inner membrane component DUF4473 PF14747.6 AAL64661.1 - 0.2 12.2 0.1 0.33 11.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) SBP_bac_5 PF00496.22 AAL64662.1 - 1.4e-25 90.1 3.2 4.1e-21 75.4 0.1 2.6 2 1 0 2 2 2 2 Bacterial extracellular solute-binding proteins, family 5 Middle Gram_pos_anchor PF00746.21 AAL64662.1 - 0.064 13.2 1.0 0.11 12.4 1.0 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif N_BRCA1_IG PF16158.5 AAL64662.1 - 0.1 13.4 0.0 0.25 12.1 0.0 1.6 1 0 0 1 1 1 0 Ig-like domain from next to BRCA1 gene PsbR PF04725.12 AAL64662.1 - 0.23 11.8 1.4 1.1 9.7 0.1 2.6 2 0 0 2 2 2 0 Photosystem II 10 kDa polypeptide PsbR Glucodextran_C PF09985.9 AAL64663.1 - 5.7e-35 120.8 0.0 3e-18 66.1 0.3 2.3 1 1 1 2 2 2 2 C-terminal binding-module, SLH-like, of glucodextranase tRNA-synt_1b PF00579.25 AAL64664.1 - 3.1e-33 115.3 0.0 6.4e-33 114.3 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA-synt_1f PF01921.18 AAL64664.1 - 0.013 14.4 0.0 1.8 7.4 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (K) HHH PF00633.23 AAL64665.1 - 0.00033 20.4 0.0 0.0008 19.2 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif Radical_SAM PF04055.21 AAL64666.1 - 6.8e-18 65.6 0.0 1.1e-17 65.0 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 AAL64666.1 - 7.8e-07 29.4 0.0 1.2e-06 28.9 0.0 1.2 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AAL64666.1 - 1.4e-06 28.4 0.0 2.3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Ribosomal_L31e PF01198.19 AAL64667.1 - 3.9e-14 52.6 0.2 5e-14 52.3 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e eIF-6 PF01912.18 AAL64668.1 - 4.4e-62 209.0 0.8 5.1e-62 208.8 0.8 1.0 1 0 0 1 1 1 1 eIF-6 family Ribosomal_L18A PF01775.17 AAL64669.1 - 8.9e-07 29.0 0.0 1.5e-06 28.3 0.0 1.4 1 1 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Prefoldin PF02996.17 AAL64670.1 - 2.9e-24 85.3 0.1 3.5e-24 85.0 0.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 AAL64670.1 - 0.00069 19.5 3.5 0.11 12.5 1.8 2.1 2 0 0 2 2 2 2 Prefoldin subunit APG17 PF04108.12 AAL64670.1 - 0.0072 15.5 0.7 2.1 7.3 0.1 2.0 2 0 0 2 2 2 2 Autophagy protein Apg17 DUF615 PF04751.14 AAL64670.1 - 0.009 16.0 2.2 0.018 15.0 2.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF615) ZapB PF06005.12 AAL64670.1 - 0.03 14.7 5.9 0.37 11.2 0.9 2.3 2 0 0 2 2 2 0 Cell division protein ZapB THOC7 PF05615.13 AAL64670.1 - 0.03 14.6 4.5 0.098 12.9 0.8 2.1 2 0 0 2 2 2 0 Tho complex subunit 7 DUF4446 PF14584.6 AAL64670.1 - 0.036 14.1 0.1 0.22 11.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Hemerythrin PF01814.23 AAL64670.1 - 0.05 14.2 1.6 0.29 11.8 0.1 2.1 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain DUF4226 PF10774.9 AAL64670.1 - 0.076 13.3 2.6 1.1 9.5 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4226) BLOC1_2 PF10046.9 AAL64670.1 - 0.096 13.0 4.1 1.3 9.4 0.4 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2203 PF09969.9 AAL64670.1 - 0.15 12.8 1.2 0.75 10.5 0.3 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) ALIX_LYPXL_bnd PF13949.6 AAL64670.1 - 0.16 11.2 4.1 0.68 9.2 4.1 1.8 1 1 0 1 1 1 0 ALIX V-shaped domain binding to HIV Seryl_tRNA_N PF02403.22 AAL64670.1 - 0.26 11.6 4.6 3.1 8.1 0.6 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FAA_hydro_N_2 PF18288.1 AAL64670.1 - 0.3 11.6 1.0 5.6 7.5 0.0 2.5 2 1 0 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 Spc7 PF08317.11 AAL64670.1 - 0.31 9.9 5.1 0.86 8.4 0.5 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Tektin PF03148.14 AAL64670.1 - 0.74 8.5 8.1 0.36 9.5 1.6 2.0 2 0 0 2 2 2 0 Tektin family APG6_N PF17675.1 AAL64670.1 - 2.5 8.7 10.1 0.65 10.5 2.5 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region SRP54 PF00448.22 AAL64671.1 - 7e-67 224.9 0.0 9.1e-67 224.5 0.0 1.1 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 AAL64671.1 - 1.8e-09 37.7 3.1 4e-09 36.6 3.1 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain CbiA PF01656.23 AAL64671.1 - 1.3e-06 28.5 0.0 6.6e-06 26.2 0.0 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.15 AAL64671.1 - 7.9e-05 22.6 0.1 0.0014 18.6 0.1 2.6 1 1 1 2 2 2 1 NTPase Zeta_toxin PF06414.12 AAL64671.1 - 0.00013 21.3 0.1 0.00048 19.5 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.6 AAL64671.1 - 0.00027 20.7 0.6 0.0006 19.6 0.1 1.9 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 AAL64671.1 - 0.00062 20.1 0.1 0.0016 18.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 AAL64671.1 - 0.001 19.5 0.0 0.003 18.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 AAL64671.1 - 0.0013 19.0 0.0 0.0039 17.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain MeaB PF03308.16 AAL64671.1 - 0.0023 17.0 0.4 0.055 12.4 0.0 2.7 1 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA PF00004.29 AAL64671.1 - 0.0024 18.3 0.0 0.014 15.8 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 AAL64671.1 - 0.0035 17.4 0.0 0.018 15.1 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 AAL64671.1 - 0.0036 17.5 0.0 0.007 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain MipZ PF09140.11 AAL64671.1 - 0.0038 16.6 0.8 13 5.0 0.0 3.6 2 1 2 4 4 4 0 ATPase MipZ cobW PF02492.19 AAL64671.1 - 0.0054 16.4 0.0 0.017 14.7 0.0 1.8 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 AAL64671.1 - 0.0085 16.5 0.0 0.014 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 AAL64671.1 - 0.011 15.4 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain VirC1 PF07015.11 AAL64671.1 - 0.013 14.8 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 VirC1 protein AAA_19 PF13245.6 AAL64671.1 - 0.023 15.0 0.1 0.059 13.7 0.0 1.6 1 1 1 2 2 2 0 AAA domain T2SSE PF00437.20 AAL64671.1 - 0.024 13.7 0.0 0.048 12.7 0.0 1.5 1 1 1 2 2 2 0 Type II/IV secretion system protein GTP_EFTU PF00009.27 AAL64671.1 - 0.044 13.3 0.0 0.081 12.5 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain NACHT PF05729.12 AAL64671.1 - 0.058 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain APS_kinase PF01583.20 AAL64671.1 - 0.06 13.2 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_31 PF13614.6 AAL64671.1 - 0.068 13.1 0.0 0.34 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 AAL64671.1 - 0.076 13.5 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 AAL64671.1 - 0.18 12.3 0.0 0.28 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain ECSCR PF15820.5 AAL64672.1 - 0.18 11.7 0.8 0.27 11.1 0.8 1.3 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Spt5-NGN PF03439.13 AAL64673.1 - 3.8e-14 52.4 1.4 4.6e-14 52.1 0.6 1.5 2 0 0 2 2 2 1 Early transcription elongation factor of RNA pol II, NGN section Ribosomal_L11 PF00298.19 AAL64674.1 - 8.6e-16 58.2 0.0 1.5e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_S30AE PF02482.19 AAL64674.1 - 0.058 14.2 0.1 0.15 12.9 0.1 1.9 1 1 0 1 1 1 0 Sigma 54 modulation protein / S30EA ribosomal protein HicA_toxin PF07927.12 AAL64674.1 - 0.19 11.8 0.4 14 5.8 0.1 2.5 2 0 0 2 2 2 0 HicA toxin of bacterial toxin-antitoxin, SAP PF02037.27 AAL64674.1 - 0.24 11.2 2.5 7.6 6.4 0.0 3.6 4 0 0 4 4 4 0 SAP domain Ribosomal_L1 PF00687.21 AAL64675.1 - 5.8e-36 124.2 0.0 7.1e-36 123.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family RL10P_insert PF17777.1 AAL64676.1 - 2.2e-21 75.6 0.0 4.5e-21 74.6 0.0 1.6 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 AAL64676.1 - 2.5e-21 75.7 0.0 4e-20 71.8 0.0 2.3 2 0 0 2 2 2 1 Ribosomal protein L10 GHMP_kinases_N PF00288.26 AAL64677.1 - 8.2e-10 38.8 0.4 1.8e-09 37.7 0.4 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 AAL64677.1 - 1.5e-09 38.0 0.3 4e-09 36.7 0.2 1.7 1 1 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 AAL64677.1 - 0.052 13.1 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 Galactokinase galactose-binding signature MtN3_slv PF03083.16 AAL64678.1 - 0.00043 20.3 1.5 0.00043 20.3 1.5 1.3 1 1 0 1 1 1 1 Sugar efflux transporter for intercellular exchange LAB_N PF07578.11 AAL64678.1 - 0.003 17.6 1.2 0.0034 17.4 1.2 1.3 1 1 0 1 1 1 1 Lipid A Biosynthesis N-terminal domain Imp-YgjV PF10688.9 AAL64678.1 - 0.0049 16.7 0.9 0.0056 16.5 0.9 1.2 1 0 0 1 1 1 1 Bacterial inner membrane protein Got1 PF04178.12 AAL64678.1 - 0.16 12.4 4.4 0.067 13.6 1.8 1.5 2 0 0 2 2 2 0 Got1/Sft2-like family PNP_UDP_1 PF01048.20 AAL64679.1 - 7.4e-40 136.7 0.4 9e-40 136.4 0.4 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily DUF2122 PF09895.9 AAL64681.1 - 4.1e-26 91.4 0.1 5.2e-26 91.1 0.1 1.1 1 0 0 1 1 1 1 RecB-family nuclease (DUF2122) QRPTase_C PF01729.19 AAL64682.1 - 2.8e-48 163.9 0.0 4.6e-48 163.2 0.0 1.3 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 AAL64682.1 - 7.4e-20 70.8 0.2 3.8e-19 68.5 0.0 2.3 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain NAD_binding_3 PF03447.16 AAL64682.1 - 3.7e-14 53.4 0.9 8e-14 52.3 0.2 1.9 2 0 0 2 2 1 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.20 AAL64682.1 - 3.7e-10 40.0 0.1 3.6e-09 36.8 0.1 2.3 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus DUF108 PF01958.18 AAL64682.1 - 2.3e-08 34.3 0.0 1.2e-07 32.0 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function DUF108 GFO_IDH_MocA PF01408.22 AAL64682.1 - 8.9e-06 26.5 0.1 2.8e-05 24.9 0.0 1.9 2 0 0 2 2 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 AAL64682.1 - 5.7e-05 23.6 0.4 0.0011 19.5 0.1 2.6 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent CoA_binding PF02629.19 AAL64682.1 - 0.0003 21.4 0.2 0.00085 20.0 0.0 1.9 2 0 0 2 2 2 1 CoA binding domain 2-Hacid_dh_C PF02826.19 AAL64682.1 - 0.00043 19.7 0.1 0.0016 17.8 0.0 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 AAL64682.1 - 0.00053 20.2 0.1 0.012 15.8 0.0 2.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 AAL64682.1 - 0.0031 17.7 0.1 0.015 15.5 0.1 2.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Gp_dh_N PF00044.24 AAL64682.1 - 0.0037 17.6 0.0 0.016 15.5 0.0 2.1 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain TrkA_N PF02254.18 AAL64682.1 - 0.013 15.7 0.8 0.039 14.2 0.1 2.2 2 0 0 2 2 2 0 TrkA-N domain DHQS PF01959.16 AAL64682.1 - 0.069 12.1 0.1 0.18 10.7 0.0 1.6 2 0 0 2 2 2 0 3-dehydroquinate synthase II Peripla_BP_1 PF00532.21 AAL64682.1 - 0.17 11.3 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family NadA PF02445.16 AAL64683.1 - 3.9e-107 357.9 0.0 4.4e-107 357.7 0.0 1.0 1 0 0 1 1 1 1 Quinolinate synthetase A protein NAD_kinase PF01513.21 AAL64684.1 - 8.6e-21 74.4 0.2 1.3e-20 73.8 0.2 1.2 1 0 0 1 1 1 1 ATP-NAD kinase HTH_5 PF01022.20 AAL64684.1 - 1.1e-09 38.0 0.0 2e-08 33.9 0.0 2.3 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_27 PF13463.6 AAL64684.1 - 1.1e-07 32.3 0.1 2.5e-07 31.1 0.1 1.7 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_11 PF08279.12 AAL64684.1 - 4e-07 29.9 0.3 1.6e-06 28.0 0.1 2.0 2 0 0 2 2 2 1 HTH domain HTH_24 PF13412.6 AAL64684.1 - 4.5e-07 29.3 1.3 6e-06 25.7 0.2 2.4 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding TrmB PF01978.19 AAL64684.1 - 3.3e-06 26.9 0.1 7.1e-06 25.8 0.1 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 AAL64684.1 - 4.7e-06 26.4 1.2 1.6e-05 24.7 0.4 2.1 2 0 0 2 2 2 1 MarR family HTH_42 PF06224.12 AAL64684.1 - 5.1e-05 23.0 0.1 6.7e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_20 PF12840.7 AAL64684.1 - 8e-05 22.6 0.2 0.00047 20.2 0.1 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 AAL64684.1 - 0.0001 22.3 0.1 0.0002 21.3 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_DeoR PF08220.12 AAL64684.1 - 0.00026 20.7 0.4 0.00078 19.1 0.1 1.9 2 0 0 2 2 2 1 DeoR-like helix-turn-helix domain MarR PF01047.22 AAL64684.1 - 0.0003 20.6 0.1 0.00056 19.8 0.1 1.4 1 0 0 1 1 1 1 MarR family HTH_9 PF08221.11 AAL64684.1 - 0.00064 19.8 0.1 0.0012 18.9 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 helix-turn-helix domain HTH_23 PF13384.6 AAL64684.1 - 0.00078 19.2 0.1 0.0019 17.9 0.1 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_IclR PF09339.10 AAL64684.1 - 0.00087 19.0 0.7 0.002 17.9 0.4 1.8 2 0 0 2 2 2 1 IclR helix-turn-helix domain Replic_Relax PF13814.6 AAL64684.1 - 0.0012 19.0 0.0 0.0023 18.0 0.0 1.4 1 0 0 1 1 1 1 Replication-relaxation GntR PF00392.21 AAL64684.1 - 0.0012 18.4 1.4 0.0028 17.2 1.0 1.8 1 1 1 2 2 2 1 Bacterial regulatory proteins, gntR family Rrf2 PF02082.20 AAL64684.1 - 0.0014 19.0 0.2 0.0029 17.9 0.2 1.5 1 0 0 1 1 1 1 Transcriptional regulator HTH_28 PF13518.6 AAL64684.1 - 0.0016 18.5 0.0 0.0041 17.2 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 AAL64684.1 - 0.007 16.0 0.1 0.015 14.9 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_36 PF13730.6 AAL64684.1 - 0.0085 16.0 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HrcA_DNA-bdg PF03444.15 AAL64684.1 - 0.011 15.4 0.1 0.029 14.0 0.1 1.7 1 1 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding TFIIE_alpha PF02002.17 AAL64684.1 - 0.013 15.4 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 TFIIE alpha subunit Ribosomal_S18 PF01084.20 AAL64684.1 - 0.014 15.6 0.2 0.023 14.9 0.2 1.3 1 0 0 1 1 1 0 Ribosomal protein S18 HTH_Crp_2 PF13545.6 AAL64684.1 - 0.015 15.3 0.1 0.031 14.3 0.1 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Fe_dep_repress PF01325.19 AAL64684.1 - 0.018 15.2 0.1 0.037 14.2 0.1 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_AsnC-type PF13404.6 AAL64684.1 - 0.018 14.8 0.9 0.018 14.8 0.9 2.4 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HxlR PF01638.17 AAL64684.1 - 0.022 14.6 0.1 0.048 13.5 0.1 1.6 1 0 0 1 1 1 0 HxlR-like helix-turn-helix PadR PF03551.14 AAL64684.1 - 0.026 14.5 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family LexA_DNA_bind PF01726.16 AAL64684.1 - 0.057 13.2 0.2 0.16 11.8 0.2 1.8 1 0 0 1 1 1 0 LexA DNA binding domain Sigma70_r4 PF04545.16 AAL64684.1 - 0.063 12.8 0.3 0.19 11.3 0.3 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 DUF742 PF05331.11 AAL64684.1 - 0.07 12.9 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF742) Cdc6_C PF09079.11 AAL64684.1 - 0.16 11.9 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain RNA_pol_Rpc34 PF05158.12 AAL64684.1 - 0.21 11.0 0.0 0.27 10.6 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit HTH_17 PF12728.7 AAL64684.1 - 0.25 11.6 1.5 1.2 9.4 0.1 2.7 3 0 0 3 3 2 0 Helix-turn-helix domain HSP20 PF00011.21 AAL64685.1 - 8.7e-09 35.5 0.0 1.8e-07 31.2 0.0 2.1 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 AAL64685.1 - 1.1e-06 28.1 0.0 1.7e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA BPD_transp_2 PF02653.16 AAL64686.1 - 1.7e-38 132.3 29.7 2.2e-38 132.0 29.7 1.1 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component BPD_transp_2 PF02653.16 AAL64687.1 - 2.3e-36 125.4 27.6 2.3e-36 125.4 27.6 2.0 2 0 0 2 2 2 2 Branched-chain amino acid transport system / permease component LapA_dom PF06305.11 AAL64687.1 - 0.033 14.0 2.9 0.033 14.0 2.9 4.6 6 0 0 6 6 6 0 Lipopolysaccharide assembly protein A domain ABC_tran PF00005.27 AAL64688.1 - 1e-42 145.9 0.0 3.7e-32 111.7 0.0 2.5 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 AAL64688.1 - 1.9e-07 31.2 0.4 0.0083 16.0 0.2 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AAL64688.1 - 3.3e-05 23.5 0.1 0.016 14.9 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Rad17 PF03215.15 AAL64688.1 - 0.0037 17.2 0.0 0.0082 16.1 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain IstB_IS21 PF01695.17 AAL64688.1 - 0.0043 16.8 0.2 14 5.4 0.0 3.4 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_15 PF13175.6 AAL64688.1 - 0.012 15.4 0.0 0.07 12.8 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 AAL64688.1 - 0.016 15.0 0.3 0.09 12.5 0.3 2.2 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AAL64688.1 - 0.021 15.4 0.0 0.032 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 AAL64688.1 - 0.024 14.1 0.0 10 5.5 0.0 3.3 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_14 PF13173.6 AAL64688.1 - 0.024 14.6 0.0 1 9.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 AAL64688.1 - 0.054 13.9 0.0 0.18 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain TsaE PF02367.17 AAL64688.1 - 0.055 13.5 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 AAL64688.1 - 0.073 13.0 0.2 0.34 10.8 0.0 2.1 3 0 0 3 3 3 0 RsgA GTPase NACHT PF05729.12 AAL64688.1 - 0.083 12.8 0.1 0.22 11.5 0.1 1.7 1 0 0 1 1 1 0 NACHT domain DLIC PF05783.11 AAL64688.1 - 0.091 11.6 0.1 0.17 10.7 0.1 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA PF00004.29 AAL64688.1 - 0.098 13.1 0.2 0.33 11.4 0.2 2.0 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AAL64688.1 - 0.11 12.8 0.1 0.58 10.4 0.0 2.2 2 1 1 3 3 3 0 AAA domain Pox_A11 PF05061.13 AAL64688.1 - 0.12 11.6 0.1 0.21 10.9 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A11 Protein SRP54 PF00448.22 AAL64688.1 - 0.14 11.7 0.2 0.35 10.5 0.2 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF3584 PF12128.8 AAL64688.1 - 0.15 9.6 0.1 0.21 9.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_13 PF13166.6 AAL64688.1 - 0.2 10.3 0.0 0.28 9.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain Bmp PF02608.14 AAL64689.1 - 3.1e-52 177.4 1.5 5.1e-52 176.7 1.5 1.2 1 0 0 1 1 1 1 ABC transporter substrate-binding protein PnrA-like UPF0444 PF15475.6 AAL64689.1 - 0.057 13.7 0.4 0.18 12.1 0.4 1.8 1 0 0 1 1 1 0 Transmembrane protein C12orf23, UPF0444 DUF5518 PF17647.1 AAL64690.1 - 0.01 16.0 11.0 0.014 15.5 11.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5518) Penicil_amidase PF01804.18 AAL64691.1 - 2e-157 526.1 0.0 2.6e-157 525.7 0.0 1.0 1 0 0 1 1 1 1 Penicillin amidase HypA PF01155.19 AAL64696.1 - 9.1e-05 22.5 0.1 0.0001 22.3 0.1 1.2 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 AAL64696.1 - 0.00026 21.0 1.1 0.00042 20.4 1.1 1.3 1 0 0 1 1 1 1 Zinc ribbon domain DZR PF12773.7 AAL64696.1 - 0.016 15.2 1.5 0.027 14.5 1.5 1.5 1 1 0 1 1 1 0 Double zinc ribbon PhnA_Zn_Ribbon PF08274.12 AAL64696.1 - 0.018 15.0 1.4 2.9 7.9 0.5 2.2 2 0 0 2 2 2 0 PhnA Zinc-Ribbon HTH_11 PF08279.12 AAL64696.1 - 0.059 13.3 0.1 2.5 8.1 0.1 2.2 2 0 0 2 2 2 0 HTH domain TFIIS_C PF01096.18 AAL64696.1 - 0.061 13.2 1.8 3.4 7.6 0.1 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) TF_Zn_Ribbon PF08271.12 AAL64696.1 - 0.065 12.8 3.0 5.6 6.6 0.1 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding zf-trcl PF13451.6 AAL64696.1 - 0.095 12.6 5.8 2.1 8.3 2.2 2.2 2 0 0 2 2 2 0 Probable zinc-ribbon domain PUB_1 PF18486.1 AAL64696.1 - 0.11 12.3 0.0 1 9.3 0.1 2.0 2 0 0 2 2 2 0 PNGase/UBA- or UBX-containing domain NRDD PF13597.6 AAL64696.1 - 0.11 11.2 0.2 0.13 11.1 0.2 1.1 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase DUF1451 PF07295.11 AAL64696.1 - 0.12 12.4 0.5 0.19 11.8 0.5 1.4 1 1 0 1 1 1 0 Zinc-ribbon containing domain zf-ribbon_3 PF13248.6 AAL64696.1 - 0.13 11.7 4.0 2.6 7.6 0.4 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2 PF00096.26 AAL64696.1 - 0.26 11.8 0.4 0.26 11.8 0.4 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type zinc_ribbon_2 PF13240.6 AAL64696.1 - 0.27 11.0 4.4 0.69 9.7 4.4 1.7 1 1 0 1 1 1 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 AAL64696.1 - 0.35 10.9 4.4 9.1 6.3 1.1 2.2 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Rubredoxin_2 PF18073.1 AAL64696.1 - 0.48 10.2 7.0 0.53 10.1 0.2 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain UPF0547 PF10571.9 AAL64696.1 - 1.1 9.4 5.8 2.2 8.4 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 FYDLN_acid PF09538.10 AAL64696.1 - 1.5 9.5 3.9 3.5 8.4 3.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) TruD PF01142.18 AAL64697.1 - 1.1e-110 370.4 0.0 4.6e-110 368.3 0.0 1.7 1 1 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) DUF362 PF04015.12 AAL64698.1 - 6e-05 23.4 0.0 0.00022 21.5 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF362) Ribosomal_L14 PF00238.19 AAL64699.1 - 6.1e-35 120.0 0.1 7e-35 119.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e HR1 PF02185.16 AAL64701.1 - 0.048 13.8 0.6 0.079 13.1 0.5 1.5 1 1 0 1 1 1 0 Hr1 repeat RecX PF02631.16 AAL64701.1 - 0.11 12.9 0.5 0.19 12.2 0.2 1.5 2 0 0 2 2 2 0 RecX family DUF2721 PF11026.8 AAL64701.1 - 0.26 11.2 0.8 0.34 10.8 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) AdoHcyase PF05221.17 AAL64702.1 - 3e-67 226.9 0.0 6.4e-67 225.8 0.0 1.5 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 AAL64702.1 - 3.6e-52 176.7 0.1 6e-52 176.0 0.1 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 AAL64702.1 - 1.7e-06 27.5 0.1 4.5e-06 26.1 0.1 1.7 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 AAL64702.1 - 0.00045 19.8 0.2 0.0011 18.5 0.2 1.7 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 AAL64702.1 - 0.0017 18.6 0.3 0.03 14.6 0.2 2.4 2 0 0 2 2 2 1 TrkA-N domain FAD-oxidase_C PF02913.19 AAL64703.1 - 0.039 13.6 0.0 0.057 13.0 0.0 1.2 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain ATPase PF06745.13 AAL64704.1 - 1.3e-85 286.4 0.0 1.6e-85 286.1 0.0 1.1 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.6 AAL64704.1 - 1.5e-05 24.6 0.0 3.1e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain GvpD PF07088.11 AAL64704.1 - 0.0022 16.7 0.0 0.003 16.2 0.0 1.1 1 0 0 1 1 1 1 GvpD gas vesicle protein DUF2075 PF09848.9 AAL64704.1 - 0.0022 17.3 0.1 0.027 13.7 0.1 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 AAL64704.1 - 0.013 15.9 0.5 0.076 13.4 0.5 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 AAL64704.1 - 0.14 12.6 0.2 1.1 9.7 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AAL64704.1 - 0.22 11.8 0.3 0.57 10.5 0.3 1.7 1 1 0 1 1 1 0 AAA domain HTH_23 PF13384.6 AAL64705.1 - 6.9e-06 25.7 0.0 2.3e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_IclR PF09339.10 AAL64705.1 - 2.6e-05 23.9 0.1 5.7e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_40 PF14493.6 AAL64705.1 - 4.2e-05 23.9 0.2 9.4e-05 22.8 0.2 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_20 PF12840.7 AAL64705.1 - 6.2e-05 23.0 0.8 0.0018 18.3 0.0 2.9 3 0 0 3 3 3 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 AAL64705.1 - 8.2e-05 22.2 0.3 0.00038 20.1 0.0 2.1 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_5 PF01022.20 AAL64705.1 - 8.5e-05 22.3 0.0 0.001 18.9 0.0 2.3 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_7 PF02796.15 AAL64705.1 - 0.00011 22.2 0.1 0.00044 20.3 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_11 PF08279.12 AAL64705.1 - 0.00014 21.8 1.4 0.0006 19.7 0.0 2.7 3 1 0 3 3 3 1 HTH domain HTH_24 PF13412.6 AAL64705.1 - 0.00014 21.4 0.1 0.0033 16.9 0.0 3.0 4 0 0 4 4 4 1 Winged helix-turn-helix DNA-binding Val_tRNA-synt_C PF10458.9 AAL64705.1 - 0.00014 22.1 4.2 0.00022 21.4 4.2 1.4 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm HTH_38 PF13936.6 AAL64705.1 - 0.00019 21.1 0.6 0.001 18.8 0.0 2.3 3 0 0 3 3 2 1 Helix-turn-helix domain HTH_DeoR PF08220.12 AAL64705.1 - 0.00036 20.2 1.1 0.0014 18.3 0.0 2.3 3 0 0 3 3 3 1 DeoR-like helix-turn-helix domain HTH_3 PF01381.22 AAL64705.1 - 0.00042 20.3 0.6 0.003 17.6 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix HTH_29 PF13551.6 AAL64705.1 - 0.00045 20.2 0.0 0.0015 18.5 0.0 1.9 2 0 0 2 2 1 1 Winged helix-turn helix Sigma70_r4 PF04545.16 AAL64705.1 - 0.0007 19.1 0.4 0.0053 16.3 0.0 2.4 2 1 1 3 3 3 1 Sigma-70, region 4 HTH_28 PF13518.6 AAL64705.1 - 0.0012 19.0 0.0 0.0028 17.7 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain GerE PF00196.19 AAL64705.1 - 0.0029 17.1 0.0 0.0077 15.8 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_Tnp_ISL3 PF13542.6 AAL64705.1 - 0.0031 16.9 0.8 0.0082 15.5 0.1 2.2 3 0 0 3 3 3 1 Helix-turn-helix domain of transposase family ISL3 HTH_AsnC-type PF13404.6 AAL64705.1 - 0.0034 17.2 0.4 0.0095 15.7 0.1 2.0 2 0 0 2 2 1 1 AsnC-type helix-turn-helix domain HTH_31 PF13560.6 AAL64705.1 - 0.0045 17.3 0.9 0.011 16.1 0.2 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.7 AAL64705.1 - 0.0057 16.5 0.1 0.022 14.7 0.1 2.0 1 1 1 2 2 2 1 MarR family Med9 PF07544.13 AAL64705.1 - 0.016 15.2 0.1 0.028 14.5 0.1 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 HTH_10 PF04967.12 AAL64705.1 - 0.018 14.8 0.1 0.13 12.1 0.0 2.2 2 0 0 2 2 2 0 HTH DNA binding domain HTH_22 PF13309.6 AAL64705.1 - 0.027 14.5 0.0 0.086 12.9 0.0 1.9 1 0 0 1 1 1 0 HTH domain YdaS_antitoxin PF15943.5 AAL64705.1 - 0.031 14.1 0.3 0.32 10.9 0.0 2.4 2 1 1 3 3 3 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT MarR PF01047.22 AAL64705.1 - 0.042 13.8 0.4 0.37 10.8 0.0 2.6 4 0 0 4 4 3 0 MarR family Fe_dep_repress PF01325.19 AAL64705.1 - 0.046 13.9 0.3 0.63 10.3 0.0 2.4 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain HTH_36 PF13730.6 AAL64705.1 - 0.048 13.6 0.0 0.35 10.9 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain DUF1804 PF08822.11 AAL64705.1 - 0.056 13.4 0.2 0.29 11.1 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1804) HTH_17 PF12728.7 AAL64705.1 - 0.062 13.5 0.1 0.19 11.9 0.1 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain Put_DNA-bind_N PF06971.13 AAL64705.1 - 0.077 13.0 0.1 0.45 10.6 0.0 2.2 2 1 0 2 2 2 0 Putative DNA-binding protein N-terminus ZnuA PF01297.17 AAL64705.1 - 0.078 12.4 0.5 0.18 11.2 0.5 1.6 1 1 0 1 1 1 0 Zinc-uptake complex component A periplasmic RP-C PF03428.13 AAL64705.1 - 0.08 12.6 0.9 0.49 10.0 0.1 2.1 2 0 0 2 2 2 0 Replication protein C N-terminal domain HTH_Tnp_1 PF01527.20 AAL64705.1 - 0.091 13.1 0.9 0.24 11.8 0.9 1.8 1 1 0 1 1 1 0 Transposase DUF2316 PF10078.9 AAL64705.1 - 0.1 12.9 0.1 1.6 9.1 0.0 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) Sigma70_r3 PF04539.16 AAL64705.1 - 0.14 12.3 2.7 4.1 7.6 0.0 2.4 2 0 0 2 2 2 0 Sigma-70 region 3 GntR PF00392.21 AAL64705.1 - 0.53 10.0 0.1 0.53 10.0 0.1 2.6 2 1 1 3 3 2 0 Bacterial regulatory proteins, gntR family IF2_N PF04760.15 AAL64705.1 - 0.72 9.7 4.8 3.4 7.6 0.0 2.9 3 0 0 3 3 2 0 Translation initiation factor IF-2, N-terminal region B3_4 PF03483.17 AAL64706.1 - 4.2e-24 85.2 0.0 6.1e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 B3/4 domain CbiA PF01656.23 AAL64707.1 - 0.00029 20.9 0.5 0.0018 18.3 0.5 2.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain cobW PF02492.19 AAL64707.1 - 0.007 16.0 0.0 0.65 9.6 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_26 PF13500.6 AAL64707.1 - 0.0099 15.7 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain MobB PF03205.14 AAL64707.1 - 0.01 15.7 0.0 0.029 14.3 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.12 AAL64707.1 - 0.016 14.5 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin ParA PF10609.9 AAL64707.1 - 0.022 14.2 2.4 0.028 13.9 0.3 2.1 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase PTS_IIB PF02302.17 AAL64707.1 - 0.031 15.0 0.6 13 6.6 0.0 3.2 3 0 0 3 3 3 0 PTS system, Lactose/Cellobiose specific IIB subunit MeaB PF03308.16 AAL64707.1 - 0.065 12.2 1.2 0.13 11.2 0.2 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Metallophos_2 PF12850.7 AAL64708.1 - 1.9e-05 24.9 0.9 0.00016 21.9 0.9 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 AAL64708.1 - 0.0026 18.3 0.3 0.016 15.7 0.3 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase FEZ PF07763.13 AAL64708.1 - 0.17 11.6 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 FEZ-like protein Thioredoxin_2 PF13098.6 AAL64710.1 - 1.7e-10 41.3 0.0 2.2e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_4 PF13462.6 AAL64710.1 - 5.3e-07 29.9 0.1 5.7e-06 26.6 0.1 1.9 1 1 0 2 2 2 1 Thioredoxin DSBA PF01323.20 AAL64710.1 - 1.8e-05 24.6 0.2 0.19 11.5 0.0 2.4 2 1 0 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin PF00085.20 AAL64710.1 - 0.02 14.9 0.0 4.9 7.2 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_3 PF13192.6 AAL64711.1 - 0.0088 16.1 0.0 0.018 15.1 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin domain MMS1_N PF10433.9 AAL64711.1 - 0.033 12.8 0.0 0.043 12.5 0.0 1.1 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Ribonuc_red_lgC PF02867.15 AAL64712.1 - 2.9e-143 478.2 0.0 3.5e-143 477.9 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 AAL64712.1 - 5.5e-13 48.7 0.2 1e-12 47.9 0.2 1.5 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 AAL64712.1 - 0.00058 20.4 0.0 0.0018 18.8 0.0 1.9 1 0 0 1 1 1 1 ATP cone domain NRDE-2 PF08424.10 AAL64712.1 - 0.028 13.5 0.0 0.05 12.7 0.0 1.3 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference CbbQ_C PF08406.10 AAL64713.1 - 0.058 13.6 0.0 0.25 11.6 0.0 1.9 2 0 0 2 2 2 0 CbbQ/NirQ/NorQ C-terminal Clathrin-link PF09268.10 AAL64713.1 - 0.82 9.1 4.4 0.78 9.2 0.4 2.7 2 1 0 2 2 2 0 Clathrin, heavy-chain linker Autophagy_act_C PF03987.15 AAL64714.1 - 0.13 12.9 0.1 0.64 10.7 0.0 2.0 2 0 0 2 2 2 0 Autophagocytosis associated protein, active-site domain tRNA-synt_2b PF00587.25 AAL64715.1 - 1.4e-32 113.1 0.0 2.2e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 AAL64715.1 - 5.7e-19 68.3 4.3 5.7e-19 68.3 4.3 1.7 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain OmpH PF03938.14 AAL64715.1 - 0.00017 21.9 0.6 0.0003 21.1 0.3 1.6 2 0 0 2 2 1 1 Outer membrane protein (OmpH-like) Dynamitin PF04912.14 AAL64715.1 - 0.00045 19.7 3.0 0.00066 19.1 3.0 1.1 1 0 0 1 1 1 1 Dynamitin THP2 PF09432.10 AAL64715.1 - 0.024 14.7 1.0 1.7 8.7 0.0 2.6 2 1 0 2 2 2 0 Tho complex subunit THP2 Fez1 PF06818.15 AAL64715.1 - 0.029 14.8 2.6 0.046 14.2 2.6 1.2 1 0 0 1 1 1 0 Fez1 DUF4618 PF15397.6 AAL64715.1 - 0.035 13.5 0.3 0.059 12.8 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) FapA PF03961.13 AAL64715.1 - 0.043 12.4 0.6 0.068 11.8 0.6 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A YabA PF06156.13 AAL64715.1 - 0.15 12.7 0.1 0.32 11.6 0.1 1.5 1 0 0 1 1 1 0 Initiation control protein YabA G10 PF01125.17 AAL64715.1 - 0.16 11.7 0.2 0.42 10.4 0.2 1.7 1 0 0 1 1 1 0 G10 protein UPF0242 PF06785.11 AAL64715.1 - 0.17 12.0 1.9 0.28 11.2 1.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Syntaxin-6_N PF09177.11 AAL64715.1 - 0.18 12.4 1.3 0.5 10.9 1.3 1.8 1 0 0 1 1 1 0 Syntaxin 6, N-terminal APG6_N PF17675.1 AAL64715.1 - 0.19 12.3 5.6 0.35 11.4 5.6 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region Cep57_MT_bd PF06657.13 AAL64715.1 - 0.24 11.9 3.8 0.55 10.7 3.8 1.6 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 GAS PF13851.6 AAL64715.1 - 0.45 9.8 4.1 0.77 9.1 4.1 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Cnn_1N PF07989.11 AAL64715.1 - 1.1 9.5 5.3 2.1 8.5 5.3 1.5 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Ax_dynein_light PF10211.9 AAL64715.1 - 1.1 9.2 5.8 1.8 8.5 5.2 1.6 1 1 0 1 1 1 0 Axonemal dynein light chain ZapB PF06005.12 AAL64715.1 - 3.3 8.2 8.7 37 4.8 8.7 2.4 1 1 0 1 1 1 0 Cell division protein ZapB AA_kinase PF00696.28 AAL64716.1 - 7.6e-26 91.2 0.1 5e-24 85.2 0.1 2.0 1 1 0 1 1 1 1 Amino acid kinase family ABC1 PF03109.16 AAL64717.1 - 0.072 13.3 0.1 0.17 12.0 0.1 1.6 1 1 0 1 1 1 0 ABC1 family HIT PF01230.23 AAL64718.1 - 5.7e-23 81.5 0.0 8.3e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 AAL64718.1 - 9.2e-15 55.1 0.0 2.1e-14 54.0 0.0 1.5 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Sigma70_r4_2 PF08281.12 AAL64719.1 - 1e-09 37.9 0.3 1.7e-09 37.2 0.3 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 GerE PF00196.19 AAL64719.1 - 2.8e-09 36.4 0.0 5.4e-09 35.5 0.0 1.5 2 0 0 2 2 1 1 Bacterial regulatory proteins, luxR family HTH_23 PF13384.6 AAL64719.1 - 1e-07 31.5 0.0 2.2e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.6 AAL64719.1 - 8.1e-07 28.7 0.1 1.5e-06 27.9 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_7 PF02796.15 AAL64719.1 - 1.4e-05 25.1 0.2 7.4e-05 22.7 0.1 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_28 PF13518.6 AAL64719.1 - 3.1e-05 24.0 0.1 5.9e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Terminase_5 PF06056.12 AAL64719.1 - 0.00021 21.1 0.0 0.00032 20.5 0.0 1.3 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) TnsD PF15978.5 AAL64719.1 - 0.00039 19.5 0.0 0.00047 19.3 0.0 1.1 1 0 0 1 1 1 1 Tn7-like transposition protein D Sigma70_ECF PF07638.11 AAL64719.1 - 0.00065 19.6 0.1 0.00099 19.0 0.1 1.2 1 0 0 1 1 1 1 ECF sigma factor HTH_40 PF14493.6 AAL64719.1 - 0.0011 19.4 0.0 0.0027 18.1 0.0 1.8 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_10 PF04967.12 AAL64719.1 - 0.0012 18.5 0.6 0.0033 17.2 0.0 1.9 2 0 0 2 2 2 1 HTH DNA binding domain HTH_24 PF13412.6 AAL64719.1 - 0.0017 17.9 0.0 0.0035 16.9 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_29 PF13551.6 AAL64719.1 - 0.0038 17.2 0.2 0.0082 16.1 0.0 1.6 2 0 0 2 2 1 1 Winged helix-turn helix HTH_11 PF08279.12 AAL64719.1 - 0.0066 16.4 0.0 0.017 15.1 0.0 1.7 1 0 0 1 1 1 1 HTH domain TrmB PF01978.19 AAL64719.1 - 0.0092 15.8 0.0 0.022 14.6 0.0 1.7 2 0 0 2 2 1 1 Sugar-specific transcriptional regulator TrmB Sigma70_r4 PF04545.16 AAL64719.1 - 0.01 15.4 0.2 0.021 14.4 0.2 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_22 PF13309.6 AAL64719.1 - 0.012 15.7 0.1 0.044 13.9 0.0 1.9 2 0 0 2 2 2 0 HTH domain Sigma70_r3 PF04539.16 AAL64719.1 - 0.017 15.2 0.1 0.03 14.4 0.1 1.4 1 0 0 1 1 1 0 Sigma-70 region 3 HTH_36 PF13730.6 AAL64719.1 - 0.017 15.0 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_8 PF02954.19 AAL64719.1 - 0.025 14.3 0.0 0.064 13.0 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family HTH_17 PF12728.7 AAL64719.1 - 0.028 14.6 0.0 0.056 13.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_30 PF13556.6 AAL64719.1 - 0.029 14.2 0.1 0.076 12.8 0.0 1.7 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_IclR PF09339.10 AAL64719.1 - 0.08 12.8 0.1 0.23 11.3 0.0 1.8 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_Crp_2 PF13545.6 AAL64719.1 - 0.082 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain PAX PF00292.18 AAL64719.1 - 0.094 12.6 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 'Paired box' domain HTH_Tnp_1 PF01527.20 AAL64719.1 - 0.1 13.0 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Transposase DUF433 PF04255.14 AAL64719.1 - 0.1 12.5 0.0 0.35 10.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF433) HTH_20 PF12840.7 AAL64719.1 - 0.11 12.5 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Phage_antitermQ PF06530.12 AAL64719.1 - 0.14 12.1 0.1 0.22 11.4 0.1 1.3 1 0 0 1 1 1 0 Phage antitermination protein Q MMR_HSR1_C PF08438.10 AAL64720.1 - 3.5e-35 121.0 0.0 5.2e-35 120.4 0.0 1.3 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 AAL64720.1 - 7.9e-20 71.0 0.0 1.6e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 AAL64720.1 - 5.8e-07 29.5 0.0 1.3e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 AAL64720.1 - 0.00052 19.6 0.0 0.0023 17.5 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 AAL64720.1 - 0.079 12.5 0.0 12 5.4 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain LexA_DNA_bind PF01726.16 AAL64720.1 - 0.095 12.5 0.0 10 6.0 0.0 2.4 2 0 0 2 2 2 0 LexA DNA binding domain PaRep2a PF07903.11 AAL64721.1 - 1.6e-14 53.8 0.0 1.7e-14 53.7 0.0 1.0 1 0 0 1 1 1 1 PaRep2a protein CBS PF00571.28 AAL64723.1 - 5.2e-60 199.7 24.8 4.1e-10 40.0 0.0 8.3 8 0 0 8 8 8 8 CBS domain IF3_N PF05198.16 AAL64723.1 - 0.067 13.5 2.6 42 4.5 0.0 4.9 5 0 0 5 5 5 0 Translation initiation factor IF-3, N-terminal domain DUF2384 PF09722.10 AAL64723.1 - 0.13 12.3 3.9 1.7 8.8 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2384) AAA PF00004.29 AAL64724.1 - 1.3e-99 329.8 0.0 3e-50 170.0 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 AAL64724.1 - 1.5e-36 123.9 2.0 7.7e-20 70.4 0.2 2.8 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 AAL64724.1 - 2.8e-33 113.9 0.5 3.2e-32 110.5 0.8 2.6 3 0 0 3 3 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 AAL64724.1 - 3.4e-15 56.2 0.0 2.3e-07 30.7 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 AAL64724.1 - 5.5e-14 52.6 0.0 1.5e-07 31.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 AAL64724.1 - 4.4e-12 46.7 0.0 1.1e-05 25.9 0.0 3.6 2 1 1 3 3 3 2 AAA ATPase domain CDC48_2 PF02933.17 AAL64724.1 - 4.7e-12 45.5 0.3 1.1e-11 44.4 0.3 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.6 AAL64724.1 - 7.1e-12 45.8 0.1 0.00045 20.5 0.0 4.2 2 2 1 4 4 4 2 AAA domain AAA_5 PF07728.14 AAL64724.1 - 2.3e-11 43.9 0.3 3.9e-05 23.7 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 AAL64724.1 - 2.4e-11 44.0 0.0 5.2e-05 23.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.10 AAL64724.1 - 4.1e-11 42.7 1.9 6e-06 26.2 0.1 3.4 3 0 0 3 3 3 2 Vps4 C terminal oligomerisation domain AAA_14 PF13173.6 AAL64724.1 - 4.9e-10 39.5 0.0 7.1e-05 22.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 AAL64724.1 - 3.4e-09 36.4 0.0 0.00029 20.2 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain IstB_IS21 PF01695.17 AAL64724.1 - 1.5e-08 34.6 0.0 0.0028 17.4 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 AAL64724.1 - 3.6e-08 34.0 0.0 0.0058 17.2 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.6 AAL64724.1 - 7.3e-07 29.6 0.0 0.0018 18.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 AAL64724.1 - 2e-06 27.3 0.2 0.027 13.9 0.1 2.7 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 AAL64724.1 - 5e-06 26.4 0.0 0.097 12.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 AAL64724.1 - 6.3e-06 26.0 0.1 0.088 12.5 0.0 3.5 2 2 0 2 2 2 2 Sigma-54 interaction domain TsaE PF02367.17 AAL64724.1 - 7.8e-06 25.9 0.1 0.46 10.5 0.0 3.1 2 1 1 3 3 3 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 AAL64724.1 - 9e-06 26.0 0.0 0.25 11.8 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_7 PF12775.7 AAL64724.1 - 4.7e-05 23.0 0.0 0.12 11.8 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_3 PF07726.11 AAL64724.1 - 6.2e-05 22.9 0.1 0.99 9.3 0.0 3.4 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 AAL64724.1 - 0.00014 21.2 0.0 0.22 10.7 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin ABC_tran PF00005.27 AAL64724.1 - 0.00025 21.6 0.0 0.41 11.2 0.0 2.7 2 0 0 2 2 2 1 ABC transporter DUF815 PF05673.13 AAL64724.1 - 0.00043 19.5 0.0 0.41 9.8 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF815) NACHT PF05729.12 AAL64724.1 - 0.00043 20.3 0.5 1.1 9.1 0.0 3.2 3 0 0 3 3 3 1 NACHT domain ATPase PF06745.13 AAL64724.1 - 0.00044 19.7 3.6 0.46 9.8 0.1 3.9 3 1 0 4 4 4 2 KaiC MazE_antitoxin PF04014.18 AAL64724.1 - 0.00088 19.2 2.9 0.0034 17.3 0.3 2.9 3 0 0 3 3 2 1 Antidote-toxin recognition MazE, bacterial antitoxin AAA_17 PF13207.6 AAL64724.1 - 0.00092 19.6 0.1 4.6 7.7 0.0 3.3 3 0 0 3 3 3 0 AAA domain PhoH PF02562.16 AAL64724.1 - 0.0012 18.3 2.0 0.2 11.1 0.0 3.1 4 0 0 4 4 2 1 PhoH-like protein Sigma54_activ_2 PF14532.6 AAL64724.1 - 0.003 17.7 0.0 2 8.5 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_25 PF13481.6 AAL64724.1 - 0.0033 17.0 7.4 3 7.4 0.2 4.1 2 2 1 3 3 3 1 AAA domain Guanylate_kin PF00625.21 AAL64724.1 - 0.0052 16.5 0.3 17 5.0 0.0 4.1 2 2 2 4 4 4 0 Guanylate kinase AAA_19 PF13245.6 AAL64724.1 - 0.0056 17.0 1.7 1.2 9.5 0.2 3.2 2 1 1 3 3 3 1 AAA domain ATPase_2 PF01637.18 AAL64724.1 - 0.0058 16.6 0.5 2 8.3 0.1 3.2 2 2 1 3 3 3 1 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 AAL64724.1 - 0.0076 16.2 1.7 7.4 6.4 0.0 3.9 3 1 1 4 4 3 0 NTPase NB-ARC PF00931.22 AAL64724.1 - 0.0093 15.2 0.1 3.4 6.8 0.0 3.1 3 0 0 3 3 3 0 NB-ARC domain AAA_30 PF13604.6 AAL64724.1 - 0.012 15.4 0.5 0.84 9.3 0.0 2.9 3 0 0 3 3 2 0 AAA domain UFD1 PF03152.14 AAL64724.1 - 0.018 14.5 0.0 2.4 7.6 0.0 2.9 2 1 1 3 3 3 0 Ubiquitin fusion degradation protein UFD1 Viral_helicase1 PF01443.18 AAL64724.1 - 0.019 14.7 0.0 0.74 9.5 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 AAL64724.1 - 0.021 14.8 0.0 7.1 6.5 0.0 2.6 2 1 0 2 2 2 0 Rad17 P-loop domain ATP-synt_ab PF00006.25 AAL64724.1 - 0.025 14.2 0.0 9.3 5.8 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_29 PF13555.6 AAL64724.1 - 0.026 14.3 0.0 8.1 6.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain PduV-EutP PF10662.9 AAL64724.1 - 0.033 13.9 0.0 0.89 9.3 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Bac_DnaA PF00308.18 AAL64724.1 - 0.035 13.9 0.0 4 7.2 0.0 3.3 4 1 0 4 4 3 0 Bacterial dnaA protein AAA_11 PF13086.6 AAL64724.1 - 0.045 13.5 0.0 1.4 8.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 AAL64724.1 - 0.066 12.3 0.1 1.1 8.3 0.0 2.1 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 ANAPC_CDC26 PF10471.9 AAL64724.1 - 0.068 14.0 0.5 17 6.3 0.1 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 AFG1_ATPase PF03969.16 AAL64724.1 - 0.087 11.7 0.0 12 4.6 0.0 2.6 2 0 0 2 2 2 0 AFG1-like ATPase DUF2075 PF09848.9 AAL64724.1 - 0.11 11.7 0.1 0.67 9.1 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Roc PF08477.13 AAL64724.1 - 0.17 12.1 0.0 11 6.3 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase IPT PF01745.16 AAL64724.1 - 0.18 11.1 0.3 4.9 6.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase ArsA_HSP20 PF17886.1 AAL64725.1 - 1.4e-15 56.6 0.1 2.3e-15 55.9 0.1 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA HSP20 PF00011.21 AAL64725.1 - 4.5e-13 49.2 3.8 1.3e-11 44.6 3.8 2.2 1 1 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.16 AAL64725.1 - 4.8e-05 24.3 0.6 7.9e-05 23.6 0.6 1.3 1 0 0 1 1 1 1 CS domain GvpH PF05455.11 AAL64725.1 - 0.00061 19.9 0.0 0.00078 19.6 0.0 1.2 1 0 0 1 1 1 1 GvpH PIH1_CS PF18201.1 AAL64725.1 - 0.017 15.6 0.1 0.024 15.1 0.1 1.3 1 0 0 1 1 1 0 PIH1 CS-like domain HECT_2 PF09814.9 AAL64725.1 - 0.14 11.0 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding PepSY_like PF11396.8 AAL64725.1 - 0.59 10.7 4.1 8.7 7.0 0.2 2.5 2 1 0 2 2 2 0 Putative beta-lactamase-inhibitor-like, PepSY-like DUF2258 PF10015.9 AAL64726.1 - 8.7e-24 83.5 1.0 1.1e-23 83.1 0.2 1.6 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2258) bZIP_2 PF07716.15 AAL64726.1 - 0.19 11.9 2.2 0.3 11.2 1.3 1.8 2 0 0 2 2 2 0 Basic region leucine zipper SPOUT_MTase_2 PF14419.6 AAL64727.1 - 1.4e-69 232.8 1.8 1.4e-69 232.8 1.8 1.6 2 0 0 2 2 2 1 AF2226-like SPOUT RNA Methylase fused to THUMP THUMP PF02926.17 AAL64727.1 - 4.8e-23 81.8 0.2 2.4e-22 79.6 0.2 2.1 1 1 1 2 2 2 1 THUMP domain FliMN_C PF01052.20 AAL64729.1 - 0.095 12.7 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Type III flagellar switch regulator (C-ring) FliN C-term Ribosomal_S11 PF00411.19 AAL64730.1 - 1.3e-42 144.6 1.0 1.8e-42 144.2 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 PaRep2b PF07775.11 AAL64730.1 - 0.19 10.2 0.0 0.34 9.3 0.0 1.4 1 1 1 2 2 2 0 PaRep2b protein Radical_SAM PF04055.21 AAL64734.1 - 3.7e-16 60.0 0.2 4.4e-15 56.5 0.0 2.4 3 0 0 3 3 3 1 Radical SAM superfamily TF_Zn_Ribbon PF08271.12 AAL64734.1 - 0.00073 19.0 2.1 0.0086 15.6 2.3 2.5 1 1 0 1 1 1 1 TFIIB zinc-binding Fer4_12 PF13353.6 AAL64734.1 - 0.0052 17.1 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain DZR PF12773.7 AAL64734.1 - 0.051 13.6 0.0 0.051 13.6 0.0 2.8 3 0 0 3 3 3 0 Double zinc ribbon A2L_zn_ribbon PF08792.10 AAL64734.1 - 0.067 12.9 2.5 8.3 6.3 0.1 3.4 3 0 0 3 3 3 0 A2L zinc ribbon domain AEP1 PF17049.5 AAL64734.1 - 0.16 11.0 0.0 0.22 10.6 0.0 1.1 1 0 0 1 1 1 0 ATPase expression protein 1 Zn-ribbon_8 PF09723.10 AAL64734.1 - 0.36 11.0 10.3 6.2 7.0 0.0 4.1 4 0 0 4 4 4 0 Zinc ribbon domain zf-ribbon_3 PF13248.6 AAL64734.1 - 0.48 9.9 7.3 0.73 9.3 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Ribosomal_L37ae PF01780.19 AAL64734.1 - 2.1 8.5 5.5 3.3 7.9 0.1 2.9 2 1 1 3 3 3 0 Ribosomal L37ae protein family DUF1272 PF06906.11 AAL64734.1 - 3.3 7.9 0.0 3.3 7.9 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1272) DUF4510 PF14971.6 AAL64735.1 - 0.085 13.2 0.1 0.11 12.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) PhoU_div PF01865.16 AAL64736.1 - 7.7e-21 74.4 9.0 9.6e-21 74.1 9.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF47 PhoU PF01895.19 AAL64736.1 - 0.00097 19.5 4.9 0.00097 19.5 4.9 2.5 2 1 0 2 2 2 1 PhoU domain DUF892 PF05974.12 AAL64736.1 - 0.0033 17.4 3.0 0.02 14.9 0.1 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF892) FliJ PF02050.16 AAL64736.1 - 0.016 15.4 1.1 0.044 14.0 0.1 2.0 2 1 0 2 2 2 0 Flagellar FliJ protein RYDR_ITPR PF01365.21 AAL64736.1 - 0.028 13.8 0.2 0.045 13.2 0.2 1.3 1 0 0 1 1 1 0 RIH domain Mito_fiss_reg PF05308.11 AAL64736.1 - 0.083 13.0 1.5 0.16 12.1 0.2 1.9 1 1 1 2 2 2 0 Mitochondrial fission regulator SesA PF17107.5 AAL64736.1 - 0.13 12.4 5.0 1.7 8.8 0.3 2.6 2 1 2 4 4 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Phage_Mu_Gam PF07352.12 AAL64736.1 - 0.14 12.1 2.2 5.2 7.0 0.1 2.5 2 1 0 2 2 2 0 Bacteriophage Mu Gam like protein HEAT_UF PF18817.1 AAL64736.1 - 0.14 12.5 1.3 18 5.7 0.1 2.9 2 0 0 2 2 2 0 Repeat of uncharacterized protein PH0542 Metal_resist PF13801.6 AAL64736.1 - 0.17 12.1 0.7 0.28 11.4 0.7 1.4 1 0 0 1 1 1 0 Heavy-metal resistance TBCC_N PF16752.5 AAL64736.1 - 0.22 12.0 1.7 7.3 7.1 0.1 2.4 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain Terminase_2 PF03592.16 AAL64736.1 - 0.68 10.4 3.4 2.7 8.5 3.4 1.9 1 1 0 1 1 1 0 Terminase small subunit HisKA PF00512.25 AAL64736.1 - 1.8 8.6 7.6 0.98 9.5 1.9 3.0 1 1 1 2 2 2 0 His Kinase A (phospho-acceptor) domain Fib_alpha PF08702.10 AAL64736.1 - 2.4 8.3 6.0 4.9 7.3 1.6 2.3 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family PHO4 PF01384.20 AAL64737.1 - 1.1 8.2 18.0 0.021 13.9 4.4 2.6 1 1 1 2 2 2 0 Phosphate transporter family Lactamase_B_3 PF13483.6 AAL64738.1 - 2e-34 118.8 0.0 2.8e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 AAL64738.1 - 1.4e-19 70.4 0.0 1.9e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 AAL64738.1 - 6.4e-06 26.3 0.3 0.0012 18.9 0.3 2.2 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Mtf2_C PF14061.6 AAL64738.1 - 0.072 13.3 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Peptidase_M48 PF01435.18 AAL64742.1 - 4.2e-32 111.5 0.2 4.8e-32 111.3 0.2 1.0 1 0 0 1 1 1 1 Peptidase family M48 OHCU_decarbox PF09349.10 AAL64742.1 - 0.15 12.5 0.1 0.3 11.6 0.1 1.6 1 1 0 1 1 1 0 OHCU decarboxylase PLDc_2 PF13091.6 AAL64743.1 - 5.1e-09 36.1 0.0 8.3e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 PLD-like domain RE_NgoFVII PF09565.10 AAL64743.1 - 2.9e-06 26.8 0.0 4e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 NgoFVII restriction endonuclease DEAD PF00270.29 AAL64745.1 - 1.6e-16 60.6 0.7 3.2e-07 30.3 0.0 2.8 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.31 AAL64745.1 - 2.8e-08 34.1 0.1 1.3e-07 31.9 0.0 2.2 2 0 0 2 2 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 AAL64745.1 - 2.4e-07 30.9 0.0 8.6e-07 29.1 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 AAL64745.1 - 2.8e-05 24.5 0.0 0.00016 22.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 AAL64745.1 - 0.00025 21.0 0.0 0.61 9.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 AAL64745.1 - 0.0057 16.4 0.0 0.082 12.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AAL64745.1 - 0.01 16.1 2.6 7.3 6.9 0.1 3.4 3 0 0 3 3 3 0 AAA domain CbiA PF01656.23 AAL64745.1 - 0.011 15.7 0.1 0.96 9.5 0.0 2.7 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.6 AAL64745.1 - 0.012 15.2 0.0 0.032 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 AAL64745.1 - 0.013 16.0 0.6 0.82 10.1 0.0 3.2 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) Baculo_PEP_C PF04513.12 AAL64745.1 - 0.056 13.5 6.0 0.15 12.1 6.0 1.7 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.9 AAL64745.1 - 0.075 13.3 2.7 0.23 11.8 2.7 1.9 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DASH_Duo1 PF08651.10 AAL64745.1 - 0.084 12.7 2.0 0.49 10.2 1.8 2.4 1 1 1 2 2 2 0 DASH complex subunit Duo1 WXG100 PF06013.12 AAL64745.1 - 0.16 12.2 0.1 0.52 10.6 0.1 1.8 1 0 0 1 1 1 0 Proteins of 100 residues with WXG HhH-GPD PF00730.25 AAL64746.1 - 7.6e-14 52.1 0.0 1e-13 51.7 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 AAL64746.1 - 4.2e-07 29.5 0.0 2.9e-05 23.7 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 AAL64746.1 - 4.3e-05 23.7 5.5 9.7e-05 22.6 5.5 1.7 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III Zn_clus PF00172.18 AAL64746.1 - 0.04 14.1 2.8 0.095 12.8 2.8 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain HHH_5 PF14520.6 AAL64746.1 - 0.11 13.1 0.0 9.5 6.9 0.0 2.4 1 1 1 2 2 2 0 Helix-hairpin-helix domain Antimicrobial_8 PF08103.11 AAL64746.1 - 1.6 9.0 0.0 1.6 9.0 0.0 2.6 3 0 0 3 3 3 0 Uperin family DNA_methylase PF00145.17 AAL64748.1 - 3.6e-52 177.8 0.0 8.9e-52 176.5 0.0 1.7 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase DUF3323 PF11796.8 AAL64748.1 - 0.013 15.4 0.2 0.02 14.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) Methyltransf_15 PF09445.10 AAL64748.1 - 0.22 11.1 0.0 0.43 10.1 0.0 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase OrfB_Zn_ribbon PF07282.11 AAL64750.1 - 7.2e-10 38.7 2.7 9.7e-10 38.2 0.1 2.4 3 0 0 3 3 3 1 Putative transposase DNA-binding domain Chorismate_bind PF00425.18 AAL64750.1 - 0.071 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 chorismate binding enzyme AAA_22 PF13401.6 AAL64751.1 - 5.4e-05 23.5 0.0 0.00024 21.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 AAL64751.1 - 7.4e-05 22.2 0.0 0.0024 17.3 0.0 2.1 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_16 PF13191.6 AAL64751.1 - 0.0053 17.2 0.2 0.0097 16.3 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain DUF853 PF05872.12 AAL64751.1 - 0.0065 15.1 0.1 0.19 10.3 0.0 2.1 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF853) TrwB_AAD_bind PF10412.9 AAL64751.1 - 0.0073 15.3 0.0 0.13 11.2 0.0 2.1 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain T2SSE PF00437.20 AAL64751.1 - 0.012 14.7 0.0 0.026 13.6 0.0 1.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_29 PF13555.6 AAL64751.1 - 0.02 14.6 0.1 0.04 13.7 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 AAL64751.1 - 0.023 14.8 0.0 0.04 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AAL64751.1 - 0.051 13.3 0.1 0.08 12.7 0.1 1.2 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 AAL64751.1 - 0.08 12.4 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein Zot PF05707.12 AAL64751.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.5 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) NACHT PF05729.12 AAL64751.1 - 0.16 11.9 0.1 0.28 11.1 0.1 1.3 1 0 0 1 1 1 0 NACHT domain PRK PF00485.18 AAL64751.1 - 0.16 11.6 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Glyco_hydro_36 PF17167.4 AAL64751.1 - 0.18 10.5 0.0 0.24 10.0 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain MobB PF03205.14 AAL64751.1 - 0.19 11.6 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATPase PF06745.13 AAL64751.1 - 0.2 11.0 0.0 0.36 10.1 0.0 1.4 1 0 0 1 1 1 0 KaiC cobW PF02492.19 AAL64751.1 - 0.26 10.9 0.0 0.41 10.2 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain PaREP1 PF05942.11 AAL64753.1 - 8.3e-27 93.4 0.6 1e-26 93.1 0.6 1.1 1 0 0 1 1 1 1 Archaeal PaREP1/PaREP8 family DUF1771 PF08590.10 AAL64753.1 - 0.09 13.2 0.3 0.2 12.1 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) PaREP1 PF05942.11 AAL64754.1 - 4.6e-25 87.8 2.0 6.1e-25 87.4 2.0 1.2 1 0 0 1 1 1 1 Archaeal PaREP1/PaREP8 family HTH_3 PF01381.22 AAL64755.1 - 2.6e-15 56.2 0.0 4.8e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 AAL64755.1 - 1.5e-12 47.7 0.4 3.7e-12 46.4 0.1 1.9 2 0 0 2 2 1 1 Helix-turn-helix domain HTH_19 PF12844.7 AAL64755.1 - 6.6e-08 32.5 0.1 4.3e-07 29.8 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_26 PF13443.6 AAL64755.1 - 1.6e-07 31.7 0.0 3.5e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_37 PF13744.6 AAL64755.1 - 0.00075 19.4 0.0 0.0021 18.0 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_35 PF13693.6 AAL64755.1 - 0.0024 17.8 0.0 0.0064 16.5 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_25 PF13413.6 AAL64755.1 - 0.0042 16.9 0.0 0.0095 15.8 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_psq PF05225.16 AAL64755.1 - 0.13 12.1 0.0 2.4 8.0 0.0 2.6 2 0 0 2 2 2 0 helix-turn-helix, Psq domain HTH_24 PF13412.6 AAL64755.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 AAL64755.1 - 0.16 11.8 0.1 0.32 10.8 0.1 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_38 PF13936.6 AAL64755.1 - 0.16 11.7 0.8 0.32 10.8 0.1 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain EamA PF00892.20 AAL64756.1 - 1.4e-27 96.5 49.1 2.5e-21 76.3 17.7 2.1 2 0 0 2 2 2 2 EamA-like transporter family GNAT_acetyltran PF12746.7 AAL64756.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase Metallophos PF00149.28 AAL64758.1 - 1.8e-08 35.2 0.0 3e-08 34.4 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AAL64758.1 - 5.4e-05 23.4 0.0 8.2e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF432 PF04254.13 AAL64759.1 - 4.8e-32 110.7 0.2 7.1e-32 110.2 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF432) MS_channel PF00924.18 AAL64760.1 - 8.6e-53 178.9 1.6 8.6e-53 178.9 1.6 1.3 2 0 0 2 2 2 1 Mechanosensitive ion channel FtsK_4TM PF13491.6 AAL64760.1 - 0.029 14.1 5.8 0.054 13.2 5.8 1.4 1 0 0 1 1 1 0 4TM region of DNA translocase FtsK/SpoIIIE DUF2768 PF10966.8 AAL64760.1 - 0.57 10.7 9.8 0.097 13.1 5.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2768) MacB_PCD PF12704.7 AAL64760.1 - 2.3 8.5 6.7 0.095 13.0 0.7 1.9 2 1 0 2 2 2 0 MacB-like periplasmic core domain UPF0020 PF01170.18 AAL64761.1 - 4.1e-21 75.6 0.0 1.9e-20 73.4 0.0 1.9 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 THUMP PF02926.17 AAL64761.1 - 4.1e-11 43.2 0.1 5.9e-11 42.7 0.1 1.3 1 0 0 1 1 1 1 THUMP domain MTS PF05175.14 AAL64761.1 - 1.7e-09 37.5 0.0 2.9e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 AAL64761.1 - 6.4e-06 26.0 0.0 2.1e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAL64761.1 - 0.00045 20.9 0.0 0.001 19.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 AAL64761.1 - 0.013 14.8 0.0 0.023 14.0 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_12 PF08242.12 AAL64761.1 - 0.016 16.0 0.0 0.031 15.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 AAL64761.1 - 0.03 14.9 0.0 0.074 13.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 AAL64761.1 - 0.034 13.6 0.0 0.058 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase T2SSE PF00437.20 AAL64762.1 - 9.9e-14 51.0 0.1 1.8e-13 50.2 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_18 PF13238.6 AAL64762.1 - 9.6e-05 22.9 0.0 0.00029 21.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAL64762.1 - 0.00052 20.4 0.0 0.001 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 AAL64762.1 - 0.0024 18.0 0.0 0.057 13.6 0.0 2.5 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.6 AAL64762.1 - 0.0041 17.4 0.0 0.011 16.0 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.6 AAL64762.1 - 0.0043 17.1 0.0 0.0095 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 AAL64762.1 - 0.0045 16.6 0.7 0.013 15.1 0.7 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 AAL64762.1 - 0.0049 16.6 0.0 0.0078 16.0 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.12 AAL64762.1 - 0.0081 15.5 0.1 0.017 14.4 0.1 1.5 1 0 0 1 1 1 1 Zeta toxin SRP54 PF00448.22 AAL64762.1 - 0.0085 15.7 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.17 AAL64762.1 - 0.0086 15.9 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein TsaE PF02367.17 AAL64762.1 - 0.011 15.7 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 AAL64762.1 - 0.011 15.4 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 AAL64762.1 - 0.012 15.4 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.12 AAL64762.1 - 0.014 15.2 0.0 0.035 13.9 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 AAL64762.1 - 0.015 15.6 0.0 0.043 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 AAL64762.1 - 0.018 14.7 0.0 0.05 13.3 0.0 1.8 1 1 0 1 1 1 0 Thymidylate kinase AAA_5 PF07728.14 AAL64762.1 - 0.019 15.0 0.0 0.044 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DnaB_C PF03796.15 AAL64762.1 - 0.027 13.8 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Sigma54_activ_2 PF14532.6 AAL64762.1 - 0.031 14.4 0.0 0.056 13.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.29 AAL64762.1 - 0.031 14.7 0.0 0.061 13.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 AAL64762.1 - 0.037 14.5 0.0 0.097 13.2 0.0 1.7 1 0 0 1 1 1 0 ABC transporter FtsK_SpoIIIE PF01580.18 AAL64762.1 - 0.04 13.3 0.0 0.071 12.4 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family NACHT PF05729.12 AAL64762.1 - 0.062 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain MeaB PF03308.16 AAL64762.1 - 0.066 12.2 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ResIII PF04851.15 AAL64762.1 - 0.073 13.1 0.1 0.33 11.0 0.0 1.8 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_24 PF13479.6 AAL64762.1 - 0.083 12.6 0.4 0.18 11.5 0.1 1.7 2 0 0 2 2 1 0 AAA domain ATPase PF06745.13 AAL64762.1 - 0.087 12.2 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 KaiC KTI12 PF08433.10 AAL64762.1 - 0.11 11.9 0.0 0.28 10.6 0.0 1.7 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_29 PF13555.6 AAL64762.1 - 0.18 11.6 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain PPV_E1_C PF00519.17 AAL64762.1 - 0.19 10.6 0.0 0.27 10.0 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase Methyltransf_11 PF08241.12 AAL64763.1 - 2.2e-15 57.1 0.0 3.4e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAL64763.1 - 3.2e-13 50.2 0.0 7.6e-13 49.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAL64763.1 - 2e-11 44.0 0.0 2.5e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAL64763.1 - 5.2e-09 36.1 0.0 3.3e-08 33.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAL64763.1 - 1.4e-08 35.4 0.0 3.5e-08 34.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AAL64763.1 - 1.1e-07 31.4 0.1 4.7e-07 29.4 0.1 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 AAL64763.1 - 4.9e-05 23.5 0.0 0.011 15.8 0.0 2.1 1 1 1 2 2 2 1 FtsJ-like methyltransferase CMAS PF02353.20 AAL64763.1 - 0.00013 21.4 0.0 0.00029 20.2 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase TehB PF03848.14 AAL64763.1 - 0.00038 19.9 0.0 0.00054 19.4 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB PCMT PF01135.19 AAL64763.1 - 0.012 15.3 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 AAL64763.1 - 0.022 14.3 0.0 0.081 12.5 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 AAL64763.1 - 0.035 13.5 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 AAL64763.1 - 0.049 13.6 0.0 0.063 13.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 AAL64763.1 - 0.051 13.5 0.0 0.096 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 AAL64763.1 - 0.052 13.1 0.0 0.074 12.6 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_8 PF05148.15 AAL64763.1 - 0.099 12.5 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase GidB PF02527.15 AAL64763.1 - 0.2 10.9 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Lactamase_B_2 PF12706.7 AAL64764.1 - 3.6e-23 82.1 0.0 2e-22 79.7 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 AAL64764.1 - 9.2e-08 32.3 0.3 3.9e-07 30.3 0.1 2.0 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 AAL64764.1 - 0.039 13.9 0.0 2.4 8.0 0.0 2.3 2 0 0 2 2 2 0 Beta-lactamase superfamily domain PaRep2b PF07775.11 AAL64765.1 - 1.1e-131 439.9 12.5 3e-129 431.8 10.0 2.0 1 1 1 2 2 2 2 PaRep2b protein PaRep2b PF07775.11 AAL64766.1 - 0.0032 16.0 0.0 0.0035 15.9 0.0 1.0 1 0 0 1 1 1 1 PaRep2b protein RrnaAD PF00398.20 AAL64767.1 - 2.1e-43 148.3 0.0 2.5e-43 148.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 AAL64767.1 - 0.00011 22.8 0.0 0.00019 22.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAL64767.1 - 0.00096 19.8 0.0 0.0023 18.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAL64767.1 - 0.025 14.4 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 AAL64767.1 - 0.032 14.0 0.0 0.046 13.5 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_31 PF13847.6 AAL64767.1 - 0.13 12.1 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.11 AAL64767.1 - 0.18 11.4 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) GatB_N PF02934.15 AAL64768.1 - 1.6e-63 214.7 0.0 2.2e-63 214.2 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GAD PF02938.14 AAL64768.1 - 5.3e-12 45.8 0.0 1.7e-11 44.2 0.0 1.9 2 0 0 2 2 2 1 GAD domain GatB_Yqey PF02637.18 AAL64768.1 - 8e-10 38.8 0.3 8.4e-09 35.5 0.3 2.3 1 1 0 1 1 1 1 GatB domain HTH_Tnp_1 PF01527.20 AAL64768.1 - 0.042 14.2 1.4 0.56 10.6 0.3 3.0 3 0 0 3 3 3 0 Transposase Ribosomal_L34e PF01199.18 AAL64769.1 - 4.5e-15 55.7 0.5 6e-15 55.3 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e Cytidylate_kin2 PF13189.6 AAL64770.1 - 6.3e-21 75.3 0.2 1.5e-18 67.6 0.2 2.0 1 1 0 1 1 1 1 Cytidylate kinase-like family Cytidylate_kin PF02224.18 AAL64770.1 - 1.3e-15 57.8 1.5 6.6e-08 32.5 0.4 2.1 1 1 1 2 2 2 2 Cytidylate kinase AAA_17 PF13207.6 AAL64770.1 - 1.1e-14 55.1 0.1 4.3e-14 53.1 0.1 2.0 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 AAL64770.1 - 2.2e-14 54.1 0.0 3e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AAL64770.1 - 3.7e-08 33.6 0.1 3.2e-06 27.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 AAL64770.1 - 7.2e-07 29.5 0.8 2.2e-05 24.6 0.8 2.5 1 1 0 1 1 1 1 Shikimate kinase PRK PF00485.18 AAL64770.1 - 0.00015 21.5 0.1 0.0042 16.8 0.0 2.2 1 1 1 2 2 2 1 Phosphoribulokinase / Uridine kinase family ADK PF00406.22 AAL64770.1 - 0.00022 21.3 0.0 0.00039 20.5 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase AAA PF00004.29 AAL64770.1 - 0.00028 21.3 0.0 0.00056 20.3 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) dNK PF01712.19 AAL64770.1 - 0.00072 19.5 0.0 1 9.2 0.0 2.3 2 0 0 2 2 2 2 Deoxynucleoside kinase AAA_16 PF13191.6 AAL64770.1 - 0.00073 20.0 0.1 0.001 19.5 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain CoaE PF01121.20 AAL64770.1 - 0.00096 18.9 0.1 0.17 11.6 0.0 2.1 2 0 0 2 2 2 1 Dephospho-CoA kinase Zeta_toxin PF06414.12 AAL64770.1 - 0.0011 18.3 0.1 0.0024 17.2 0.1 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.6 AAL64770.1 - 0.0024 18.1 0.1 0.0045 17.3 0.1 1.6 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 AAL64770.1 - 0.0037 16.5 0.8 0.0074 15.5 0.1 1.7 2 0 0 2 2 2 1 NB-ARC domain NACHT PF05729.12 AAL64770.1 - 0.0047 16.9 0.0 0.0097 15.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain NTPase_1 PF03266.15 AAL64770.1 - 0.0052 16.7 0.0 0.0078 16.1 0.0 1.3 1 0 0 1 1 1 1 NTPase AAA_5 PF07728.14 AAL64770.1 - 0.0055 16.7 0.0 0.0096 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 AAL64770.1 - 0.0061 16.3 0.0 0.013 15.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 AAL64770.1 - 0.0063 16.5 0.1 0.016 15.2 0.0 1.7 1 1 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE KTI12 PF08433.10 AAL64770.1 - 0.013 14.9 0.1 0.019 14.4 0.1 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_22 PF13401.6 AAL64770.1 - 0.016 15.5 0.1 0.034 14.4 0.0 1.6 2 0 0 2 2 1 0 AAA domain Thymidylate_kin PF02223.17 AAL64770.1 - 0.022 14.5 0.1 7.9 6.1 0.0 2.5 2 1 0 3 3 3 0 Thymidylate kinase CPT PF07931.12 AAL64770.1 - 0.039 13.8 0.1 0.49 10.2 0.0 2.1 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Viral_helicase1 PF01443.18 AAL64770.1 - 0.047 13.4 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase APS_kinase PF01583.20 AAL64770.1 - 0.061 13.2 0.1 0.32 10.9 0.0 2.0 1 1 0 2 2 2 0 Adenylylsulphate kinase DUF2075 PF09848.9 AAL64770.1 - 0.064 12.5 0.0 0.091 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 AAL64770.1 - 0.07 13.5 0.1 0.25 11.7 0.1 1.8 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 AAL64770.1 - 0.076 12.7 0.1 0.19 11.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 AAL64770.1 - 0.15 11.4 0.1 0.3 10.4 0.1 1.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 AAL64770.1 - 0.16 11.2 0.1 0.45 9.8 0.0 1.7 2 0 0 2 2 2 0 KaiC RNA_helicase PF00910.22 AAL64770.1 - 0.2 12.1 0.0 0.31 11.4 0.0 1.3 1 0 0 1 1 1 0 RNA helicase Pyr_redox_2 PF07992.14 AAL64771.1 - 2.9e-31 108.8 0.0 4.2e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAL64771.1 - 6.4e-10 39.5 2.5 1.6e-05 25.3 0.3 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AAL64771.1 - 9e-07 28.3 2.1 0.018 14.2 0.3 3.2 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_3 PF13738.6 AAL64771.1 - 1.7e-06 27.5 6.5 0.00087 18.6 0.1 3.4 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AAL64771.1 - 3.6e-06 26.5 1.1 0.0025 17.1 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 AAL64771.1 - 1.2e-05 25.4 3.2 0.00019 21.6 0.3 2.6 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 AAL64771.1 - 1.7e-05 24.4 1.4 0.13 11.6 1.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 AAL64771.1 - 5e-05 22.7 0.3 0.1 11.9 0.0 2.6 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 AAL64771.1 - 7.4e-05 22.8 0.4 0.027 14.5 0.1 3.0 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase FMO-like PF00743.19 AAL64771.1 - 0.00013 20.6 0.0 0.015 13.8 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_7 PF13241.6 AAL64771.1 - 0.00095 19.6 0.9 0.93 10.0 0.1 2.6 2 1 0 2 2 2 2 Putative NAD(P)-binding HI0933_like PF03486.14 AAL64771.1 - 0.0012 17.6 4.8 0.0013 17.5 0.4 2.6 3 0 0 3 3 3 1 HI0933-like protein Amino_oxidase PF01593.24 AAL64771.1 - 0.0015 17.9 0.1 1.1 8.5 0.0 2.5 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.24 AAL64771.1 - 0.0018 17.9 2.9 2.3 7.7 0.9 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 AAL64771.1 - 0.0035 16.7 0.1 0.73 9.2 0.0 3.0 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 AAL64771.1 - 0.0037 17.2 0.9 0.014 15.3 0.1 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 AAL64771.1 - 0.0089 15.1 7.3 1.2 8.1 0.2 3.3 4 0 0 4 4 4 2 Glucose inhibited division protein A GIDE PF12483.8 AAL64771.1 - 0.01 15.3 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 E3 Ubiquitin ligase K_oxygenase PF13434.6 AAL64771.1 - 0.053 12.6 0.0 0.34 10.0 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) IlvN PF07991.12 AAL64771.1 - 0.062 12.9 0.1 8.9 5.8 0.1 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Thi4 PF01946.17 AAL64771.1 - 0.1 11.8 0.8 0.27 10.5 0.1 1.8 2 0 0 2 2 2 0 Thi4 family F420_oxidored PF03807.17 AAL64771.1 - 0.19 12.3 2.0 20 5.9 0.1 3.1 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_9 PF13454.6 AAL64771.1 - 0.7 9.9 2.6 0.59 10.1 0.4 2.0 3 0 0 3 3 2 0 FAD-NAD(P)-binding Fibrillarin PF01269.17 AAL64772.1 - 3.6e-104 346.8 0.0 4.1e-104 346.6 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin PCMT PF01135.19 AAL64772.1 - 1.4e-08 34.7 0.0 2.1e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GCD14 PF08704.10 AAL64772.1 - 0.0089 15.7 0.0 0.016 14.9 0.0 1.4 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltr_RsmB-F PF01189.17 AAL64772.1 - 0.009 15.7 0.0 0.017 14.7 0.0 1.5 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Ubie_methyltran PF01209.18 AAL64772.1 - 0.017 14.5 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family LBR_tudor PF09465.10 AAL64772.1 - 0.08 12.8 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain Nop PF01798.18 AAL64773.1 - 7.8e-68 228.4 0.0 1.1e-67 227.9 0.0 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin vWA-TerF-like PF10138.9 AAL64773.1 - 0.056 13.5 0.1 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 vWA found in TerF C terminus CAP_N PF01213.19 AAL64773.1 - 8.7 5.7 9.9 15 4.9 9.9 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PaREP1 PF05942.11 AAL64774.1 - 5.1e-33 113.4 0.4 8.1e-33 112.8 0.4 1.3 1 0 0 1 1 1 1 Archaeal PaREP1/PaREP8 family TrwB_AAD_bind PF10412.9 AAL64774.1 - 0.12 11.3 0.1 0.17 10.8 0.1 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Beta-lactamase PF00144.24 AAL64775.1 - 1.7e-66 224.7 0.0 2.2e-66 224.4 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Pab87_oct PF13969.6 AAL64775.1 - 1.3e-29 102.1 0.3 2.5e-29 101.2 0.3 1.5 1 0 0 1 1 1 1 Pab87 octamerisation domain Imm26 PF15428.6 AAL64775.1 - 0.21 11.8 1.2 2.2 8.5 0.1 2.7 2 1 1 3 3 3 0 Immunity protein 26 Rad51 PF08423.11 AAL64776.1 - 5.3e-41 140.6 0.0 6.2e-41 140.3 0.0 1.1 1 0 0 1 1 1 1 Rad51 ATPase PF06745.13 AAL64776.1 - 1.2e-09 37.9 0.0 5.1e-09 35.8 0.0 2.0 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.6 AAL64776.1 - 3.5e-08 33.9 0.1 1.1e-07 32.4 0.1 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_25 PF13481.6 AAL64776.1 - 2.4e-06 27.3 0.1 4.3e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 AAL64776.1 - 4.3e-05 23.3 0.0 8.6e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain HHH PF00633.23 AAL64776.1 - 0.00038 20.2 0.2 0.0013 18.5 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif Cdd1 PF11731.8 AAL64776.1 - 0.00058 20.1 0.0 0.0012 19.1 0.0 1.5 1 0 0 1 1 1 1 Pathogenicity locus PhoH PF02562.16 AAL64776.1 - 0.0079 15.7 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein DNA_pol_lambd_f PF10391.9 AAL64776.1 - 0.0095 15.8 0.0 0.029 14.2 0.0 1.9 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_3 PF12836.7 AAL64776.1 - 0.011 16.0 0.1 0.027 14.7 0.1 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF4332 PF14229.6 AAL64776.1 - 0.03 14.6 0.1 0.061 13.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) Bac_DnaA PF00308.18 AAL64776.1 - 0.045 13.6 0.0 0.13 12.1 0.0 1.7 1 1 0 1 1 1 0 Bacterial dnaA protein AAA_10 PF12846.7 AAL64776.1 - 0.08 11.8 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain DUF4262 PF14081.6 AAL64776.1 - 0.14 12.4 0.3 5.4 7.2 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4262) Antimicrobial15 PF08110.12 AAL64776.1 - 0.15 12.3 1.4 9.2 6.7 0.1 2.5 2 0 0 2 2 2 0 Ocellatin family IMS_HHH PF11798.8 AAL64776.1 - 0.15 12.4 0.3 0.44 11.0 0.0 1.9 2 0 0 2 2 1 0 IMS family HHH motif SAM_2 PF07647.17 AAL64776.1 - 0.16 12.1 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) HTH_45 PF14947.6 AAL64779.1 - 1.1e-10 41.4 0.1 1.3e-10 41.1 0.1 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix RelB_N PF18506.1 AAL64779.1 - 0.049 13.4 3.4 0.22 11.3 0.4 2.8 3 0 0 3 3 3 0 RelB Antitoxin alpha helical domain DUF2250 PF10007.9 AAL64779.1 - 0.06 13.5 0.3 0.17 12.0 0.1 1.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) GPS2_interact PF15784.5 AAL64779.1 - 0.13 12.7 0.0 0.17 12.3 0.0 1.2 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain CHAT PF12770.7 AAL64780.1 - 0.0071 15.8 0.1 0.012 15.0 0.1 1.3 1 0 0 1 1 1 1 CHAT domain MgtC PF02308.16 AAL64780.1 - 0.085 13.2 3.9 0.13 12.6 3.9 1.4 1 1 0 1 1 1 0 MgtC family PrgI PF12666.7 AAL64780.1 - 2.2 9.1 5.6 1.5 9.6 1.0 2.3 1 1 1 2 2 2 0 PrgI family protein DUF2070 PF09843.9 AAL64780.1 - 4.4 5.5 6.9 5.5 5.2 6.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) AAA_31 PF13614.6 AAL64781.1 - 2.4e-20 73.2 0.0 3.2e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 AAL64781.1 - 3e-14 53.2 0.0 4.2e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 AAL64781.1 - 6.8e-08 32.3 0.0 1.3e-06 28.1 0.0 2.1 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 AAL64781.1 - 3.4e-06 26.7 0.0 0.00046 19.8 0.1 2.2 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ ArsA_ATPase PF02374.15 AAL64781.1 - 1.2e-05 24.7 0.0 4.9e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.11 AAL64781.1 - 0.00057 19.3 0.4 0.0034 16.7 0.1 2.2 3 0 0 3 3 3 1 ATPase MipZ VirC1 PF07015.11 AAL64781.1 - 0.0011 18.4 0.1 0.0026 17.1 0.0 1.7 2 0 0 2 2 2 1 VirC1 protein AAA_25 PF13481.6 AAL64781.1 - 0.0034 17.0 3.1 0.0037 16.9 0.6 2.1 2 1 0 2 2 2 1 AAA domain CLP1_P PF16575.5 AAL64781.1 - 0.0049 16.7 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Fer4_NifH PF00142.18 AAL64781.1 - 0.015 14.8 0.0 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 AAL64781.1 - 0.016 14.8 0.0 0.24 11.0 0.0 2.5 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain MeaB PF03308.16 AAL64781.1 - 0.022 13.7 0.0 0.085 11.8 0.1 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 AAL64781.1 - 0.12 12.8 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 AAL64781.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arg_decarbox_C PF17944.1 AAL64782.1 - 0.052 14.1 0.5 0.077 13.6 0.5 1.3 1 0 0 1 1 1 0 Arginine decarboxylase C-terminal helical extension Acetyltransf_1 PF00583.25 AAL64783.1 - 1e-09 38.6 0.1 1.4e-09 38.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAL64783.1 - 4.9e-07 30.1 0.0 7.3e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAL64783.1 - 2.5e-06 27.3 0.0 4.9e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 AAL64783.1 - 2.4e-05 24.3 0.0 3.4e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AAL64783.1 - 0.00016 22.3 0.0 0.00023 21.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AAL64783.1 - 0.033 14.3 0.0 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Aldo_ket_red PF00248.21 AAL64784.1 - 9.2e-66 222.0 0.0 5.4e-64 216.2 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family ATP-grasp_5 PF13549.6 AAL64785.1 - 5.6e-75 251.6 0.2 6.4e-75 251.4 0.2 1.0 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_2 PF08442.10 AAL64785.1 - 2.8e-05 23.8 0.1 4.1e-05 23.2 0.1 1.6 1 1 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 AAL64785.1 - 0.0018 17.9 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp PF02222.22 AAL64785.1 - 0.0037 16.9 0.0 0.0061 16.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 AAL64785.1 - 0.033 13.7 0.1 0.057 12.9 0.1 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Succ_CoA_lig PF13607.6 AAL64786.1 - 4.5e-50 169.0 2.5 2.1e-48 163.6 0.6 3.1 4 0 0 4 4 4 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 AAL64786.1 - 1.1e-23 83.9 1.1 6e-23 81.6 0.3 2.5 3 0 0 3 3 3 1 CoA binding domain CoA_binding PF02629.19 AAL64786.1 - 9.6e-12 45.4 0.2 4.3e-11 43.3 0.1 2.1 2 0 0 2 2 2 1 CoA binding domain GFO_IDH_MocA PF01408.22 AAL64786.1 - 0.0096 16.7 0.0 2.8 8.8 0.0 2.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 AAL64786.1 - 0.084 13.5 0.3 0.73 10.5 0.1 2.6 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent DUF348 PF03990.14 AAL64786.1 - 0.097 12.4 0.1 13 5.6 0.0 3.1 3 0 0 3 3 3 0 G5-linked-Ubiquitin-like domain Ligase_CoA PF00549.19 AAL64786.1 - 0.17 11.7 0.0 0.6 9.9 0.0 2.0 2 1 0 2 2 2 0 CoA-ligase MS_channel PF00924.18 AAL64788.1 - 1.8e-19 70.1 1.3 1.8e-19 70.1 1.3 2.1 1 1 0 2 2 2 1 Mechanosensitive ion channel Ras PF00071.22 AAL64789.1 - 3.9e-09 36.3 0.0 5.5e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Ras family FeoB_N PF02421.18 AAL64789.1 - 6.9e-09 35.4 0.0 8.8e-09 35.1 0.0 1.1 1 0 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 AAL64789.1 - 5.5e-08 32.4 0.0 7.1e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 AAL64789.1 - 3e-06 27.3 0.0 3.5e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 AAL64789.1 - 3.6e-06 26.8 0.1 1.8e-05 24.5 0.1 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 AAL64789.1 - 6.8e-05 23.1 0.1 0.00022 21.4 0.1 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 AAL64789.1 - 0.00077 18.9 0.0 0.00098 18.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 AAL64789.1 - 0.002 18.1 0.4 0.058 13.3 0.2 2.4 2 1 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 AAL64789.1 - 0.0033 17.0 0.2 0.023 14.2 0.0 1.9 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 AAL64789.1 - 0.13 12.7 0.2 0.13 12.6 0.2 1.4 1 1 0 1 1 1 0 AAA ATPase domain CbiA PF01656.23 AAL64789.1 - 0.14 12.2 0.3 0.41 10.7 0.1 1.7 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain ABC_tran PF00005.27 AAL64789.1 - 0.29 11.7 0.4 0.71 10.4 0.3 1.5 1 1 0 1 1 1 0 ABC transporter ParA PF10609.9 AAL64789.1 - 0.37 10.2 0.9 3.8 6.9 0.6 2.0 1 1 1 2 2 2 0 NUBPL iron-transfer P-loop NTPase ABC_tran PF00005.27 AAL64790.1 - 0.0002 21.9 0.0 0.00041 20.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 AAL64790.1 - 0.0044 17.4 0.9 0.016 15.6 0.0 2.3 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 AAL64790.1 - 0.014 15.6 0.0 0.06 13.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 AAL64790.1 - 0.015 15.0 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 AAL64790.1 - 0.019 15.5 0.0 0.083 13.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 AAL64790.1 - 0.072 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 AAL64790.1 - 0.12 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 AAL64790.1 - 0.13 11.8 0.0 0.32 10.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 AAL64790.1 - 0.17 11.9 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 AAL64790.1 - 0.18 10.9 0.0 0.33 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 AAL64790.1 - 0.26 10.8 0.0 0.42 10.1 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region NTP_transf_3 PF12804.7 AAL64790.1 - 0.6 10.4 3.0 1.9 8.8 0.2 2.8 2 1 0 2 2 2 0 MobA-like NTP transferase domain TPR_10 PF13374.6 AAL64790.1 - 2.6 8.0 4.9 11 6.0 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_L40e PF01020.17 AAL64791.1 - 8e-07 28.9 5.2 8.9e-07 28.7 5.2 1.1 1 0 0 1 1 1 1 Ribosomal L40e family zinc_ribbon_2 PF13240.6 AAL64791.1 - 3.2e-05 23.5 2.6 4.1e-05 23.1 2.6 1.2 1 0 0 1 1 1 1 zinc-ribbon domain zf-RanBP PF00641.18 AAL64791.1 - 0.00044 19.5 2.0 0.00057 19.1 2.0 1.2 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DZR PF12773.7 AAL64791.1 - 0.002 18.1 2.0 0.0026 17.8 2.0 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.6 AAL64791.1 - 0.027 13.9 2.8 0.035 13.5 2.8 1.2 1 0 0 1 1 1 0 zinc-ribbon domain HypA PF01155.19 AAL64791.1 - 0.034 14.2 0.3 0.035 14.1 0.3 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf_C2H2_13 PF18508.1 AAL64791.1 - 0.047 13.3 0.1 0.08 12.5 0.1 1.5 1 0 0 1 1 1 0 Zinc finger domain DUF35_N PF12172.8 AAL64791.1 - 0.12 12.3 5.1 0.21 11.5 5.1 1.5 1 1 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DHHC PF01529.20 AAL64791.1 - 1.1 9.3 3.3 1.3 9.2 3.3 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase DNA_RNApol_7kD PF03604.13 AAL64791.1 - 5 6.9 12.8 22 4.8 10.7 2.6 2 1 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit AP_endonuc_2 PF01261.24 AAL64792.1 - 1.2e-24 87.0 0.1 1.5e-24 86.6 0.1 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel UvdE PF03851.14 AAL64792.1 - 0.021 14.1 0.0 0.038 13.2 0.0 1.4 1 0 0 1 1 1 0 UV-endonuclease UvdE FbpA PF05833.11 AAL64793.1 - 2.2e-30 105.8 0.2 3e-30 105.4 0.2 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 AAL64793.1 - 9e-21 74.6 0.0 1.8e-20 73.6 0.0 1.5 1 0 0 1 1 1 1 NFACT protein RNA binding domain NFACT-R_2 PF18297.1 AAL64793.1 - 0.0082 16.3 0.0 0.023 14.9 0.0 1.8 1 0 0 1 1 1 1 NFACT protein RNA binding domain AAA_13 PF13166.6 AAL64793.1 - 0.018 13.7 11.3 0.025 13.2 11.3 1.1 1 0 0 1 1 1 0 AAA domain Occludin_ELL PF07303.13 AAL64793.1 - 0.02 15.6 8.7 0.49 11.1 1.7 2.3 2 0 0 2 2 2 0 Occludin homology domain DUF2205 PF10224.9 AAL64793.1 - 0.033 14.2 1.0 0.033 14.2 1.0 2.5 2 0 0 2 2 2 0 Short coiled-coil protein CASP_C PF08172.12 AAL64793.1 - 0.04 13.2 7.1 0.071 12.4 0.8 2.1 2 0 0 2 2 2 0 CASP C terminal Laminin_I PF06008.14 AAL64793.1 - 0.058 13.1 12.1 0.095 12.4 6.2 2.2 1 1 1 2 2 2 0 Laminin Domain I Spc24 PF08286.11 AAL64793.1 - 0.075 13.3 8.1 0.62 10.3 0.7 2.4 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF4763 PF15960.5 AAL64793.1 - 0.097 12.0 11.6 0.51 9.6 1.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) COG5 PF10392.9 AAL64793.1 - 0.1 12.8 3.5 1.9 8.6 0.4 2.4 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DprA_WH PF17782.1 AAL64793.1 - 0.13 12.4 1.0 0.35 11.0 0.1 2.1 2 0 0 2 2 2 0 DprA winged helix domain APG6_N PF17675.1 AAL64793.1 - 0.15 12.6 19.0 1.1 9.8 3.8 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region ZapB PF06005.12 AAL64793.1 - 0.17 12.3 20.9 1.4 9.4 5.0 2.5 2 0 0 2 2 2 0 Cell division protein ZapB GCN5L1 PF06320.13 AAL64793.1 - 0.18 12.0 7.3 2.5 8.3 0.3 2.3 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) TMF_DNA_bd PF12329.8 AAL64793.1 - 0.22 11.5 23.4 0.23 11.5 12.6 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Cauli_AT PF03233.13 AAL64793.1 - 0.25 11.3 5.8 2 8.3 1.8 2.5 2 0 0 2 2 2 0 Aphid transmission protein YabA PF06156.13 AAL64793.1 - 0.43 11.2 9.2 0.81 10.4 1.1 2.6 2 1 0 2 2 2 0 Initiation control protein YabA THOC7 PF05615.13 AAL64793.1 - 0.54 10.5 9.6 0.97 9.7 0.3 2.3 2 0 0 2 2 2 0 Tho complex subunit 7 HIP1_clath_bdg PF16515.5 AAL64793.1 - 0.71 10.5 13.9 0.82 10.3 3.6 2.3 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 bZIP_1 PF00170.21 AAL64793.1 - 0.84 9.8 13.0 1.4 9.1 1.2 2.6 2 0 0 2 2 2 0 bZIP transcription factor DUF1043 PF06295.12 AAL64793.1 - 0.89 9.6 5.1 0.94 9.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) FemAB PF02388.16 AAL64793.1 - 0.97 8.2 11.5 2.7 6.8 0.9 3.0 3 0 0 3 3 3 0 FemAB family ING PF12998.7 AAL64793.1 - 1.8 9.2 6.5 5.3 7.7 6.5 1.8 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding DUF4140 PF13600.6 AAL64793.1 - 2.2 8.8 8.4 9 6.8 2.0 2.7 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) TPR_MLP1_2 PF07926.12 AAL64793.1 - 2.9 8.0 18.7 5.6 7.0 1.9 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Snf7 PF03357.21 AAL64793.1 - 3 7.4 12.8 0.95 9.0 2.1 2.3 2 0 0 2 2 2 0 Snf7 Fzo_mitofusin PF04799.13 AAL64793.1 - 4.3 6.9 8.8 1.4 8.5 1.0 2.3 2 0 0 2 2 2 0 fzo-like conserved region V_ATPase_I PF01496.19 AAL64793.1 - 4.8 5.0 6.7 7.2 4.4 6.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4200 PF13863.6 AAL64793.1 - 6 7.3 22.6 5.3 7.5 7.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Uso1_p115_C PF04871.13 AAL64793.1 - 6.2 7.2 16.2 2.6 8.4 5.8 2.3 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF4407 PF14362.6 AAL64793.1 - 6.6 6.0 9.2 13 5.0 9.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Rootletin PF15035.6 AAL64793.1 - 7.3 6.6 14.4 13 5.7 14.3 1.4 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion TSC22 PF01166.18 AAL64793.1 - 7.9 6.9 7.6 4.9 7.5 0.9 3.3 3 1 0 3 3 3 0 TSC-22/dip/bun family Seryl_tRNA_N PF02403.22 AAL64793.1 - 8.3 6.7 19.9 9.1 6.6 9.1 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.12 AAL64793.1 - 8.5 6.4 7.0 17 5.5 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) XhlA PF10779.9 AAL64793.1 - 9.2 6.5 11.1 1.7 8.9 2.8 3.1 2 1 1 3 3 3 0 Haemolysin XhlA Herpes_UL6 PF01763.16 AAL64793.1 - 9.4 4.6 11.8 1.2 7.6 4.3 2.2 1 1 1 2 2 2 0 Herpesvirus UL6 like Prefoldin_2 PF01920.20 AAL64793.1 - 9.5 6.2 18.4 4.3 7.3 2.7 2.5 2 0 0 2 2 2 0 Prefoldin subunit CLZ PF16526.5 AAL64793.1 - 9.9 6.6 17.3 1.2 9.5 7.7 2.9 1 1 2 3 3 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Mut7-C PF01927.16 AAL64796.1 - 1.2e-21 77.4 0.4 1.6e-21 77.0 0.4 1.1 1 0 0 1 1 1 1 Mut7-C RNAse domain zf-C2H2_3 PF13878.6 AAL64796.1 - 0.016 15.0 0.7 0.1 12.4 0.0 2.2 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO Zn-ribbon_8 PF09723.10 AAL64796.1 - 0.053 13.6 3.1 0.36 11.0 0.0 2.6 2 1 1 3 3 3 0 Zinc ribbon domain ADK_lid PF05191.14 AAL64796.1 - 0.069 13.1 0.9 1.6 8.7 0.0 2.4 2 0 0 2 2 2 0 Adenylate kinase, active site lid DUF1272 PF06906.11 AAL64796.1 - 0.34 11.0 5.8 0.42 10.7 0.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1272) HalOD2 PF18547.1 AAL64796.1 - 0.36 10.8 5.5 0.75 9.7 5.5 1.6 1 0 0 1 1 1 0 Halobacterial output domain 2 NMD3 PF04981.13 AAL64796.1 - 0.44 10.0 5.8 0.63 9.5 5.8 1.2 1 0 0 1 1 1 0 NMD3 family DNA_RNApol_7kD PF03604.13 AAL64796.1 - 1.1 9.0 6.4 14 5.5 0.1 2.6 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-ribbon_3 PF13248.6 AAL64796.1 - 5.4 6.6 10.3 1.3 8.5 0.5 2.9 2 1 0 2 2 2 0 zinc-ribbon domain DHO_dh PF01180.21 AAL64797.1 - 3.1e-24 85.7 0.0 3.6e-23 82.2 0.0 2.0 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase His_biosynth PF00977.21 AAL64797.1 - 0.065 12.7 0.0 0.36 10.3 0.0 1.8 2 0 0 2 2 2 0 Histidine biosynthesis protein Pribosyltran PF00156.27 AAL64798.1 - 6.8e-19 67.9 0.3 9.4e-19 67.5 0.3 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 AAL64798.1 - 0.0066 15.9 0.0 0.0087 15.5 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 AAL64798.1 - 0.028 13.9 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase PyrI PF01948.18 AAL64799.1 - 8.9e-35 118.8 1.6 1.1e-34 118.6 1.6 1.1 1 0 0 1 1 1 1 Aspartate carbamoyltransferase regulatory chain, allosteric domain PyrI_C PF02748.15 AAL64799.1 - 1.3e-13 50.6 0.8 1.8e-13 50.1 0.1 1.6 2 0 0 2 2 2 1 Aspartate carbamoyltransferase regulatory chain, metal binding domain HTH_19 PF12844.7 AAL64799.1 - 0.029 14.4 0.0 0.098 12.7 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain ANF_receptor PF01094.28 AAL64800.1 - 7.8e-47 160.1 0.0 9.9e-47 159.7 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 AAL64800.1 - 7.7e-43 147.5 1.0 9.1e-43 147.2 1.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein Peripla_BP_5 PF13433.6 AAL64800.1 - 9.6e-10 38.0 0.0 0.00031 19.8 0.0 2.1 2 0 0 2 2 2 2 Periplasmic binding protein domain DUF2561 PF10812.8 AAL64800.1 - 0.0058 16.7 0.3 0.011 15.7 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2561) ABC_tran PF00005.27 AAL64801.1 - 6.4e-28 98.0 0.0 8.4e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAL64801.1 - 3.5e-11 43.4 0.7 0.00011 22.2 0.1 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AAL64801.1 - 6.1e-05 23.6 0.1 0.00011 22.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 AAL64801.1 - 7.7e-05 22.2 0.3 0.00067 19.1 0.3 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 AAL64801.1 - 0.00011 22.2 0.2 0.00018 21.4 0.2 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 AAL64801.1 - 0.00042 20.0 0.1 0.00096 18.9 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 AAL64801.1 - 0.00095 18.9 0.1 0.0021 17.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AAL64801.1 - 0.0012 19.1 0.0 0.0061 16.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_27 PF13514.6 AAL64801.1 - 0.0031 17.1 0.0 0.0054 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAL64801.1 - 0.0043 17.5 0.1 0.0058 17.0 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 AAL64801.1 - 0.0054 16.3 0.0 0.085 12.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.9 AAL64801.1 - 0.0063 15.4 0.1 0.69 8.6 0.2 2.2 2 0 0 2 2 2 1 Predicted ATPase of the ABC class MMR_HSR1 PF01926.23 AAL64801.1 - 0.021 14.9 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase TniB PF05621.11 AAL64801.1 - 0.035 13.5 0.1 0.38 10.1 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein AAA_15 PF13175.6 AAL64801.1 - 0.037 13.8 0.0 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 AAL64801.1 - 0.043 13.7 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 AAL64801.1 - 0.045 13.8 0.0 0.12 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 AAL64801.1 - 0.058 13.1 0.0 0.16 11.7 0.1 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein T2SSE PF00437.20 AAL64801.1 - 0.059 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.29 AAL64801.1 - 0.073 13.5 0.1 0.12 12.9 0.1 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 AAL64801.1 - 0.078 13.2 0.0 0.15 12.3 0.0 1.5 2 0 0 2 2 1 0 AAA domain Dynamin_N PF00350.23 AAL64801.1 - 0.079 13.0 0.2 0.12 12.4 0.2 1.3 1 0 0 1 1 1 0 Dynamin family cobW PF02492.19 AAL64801.1 - 0.092 12.3 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 AAL64801.1 - 0.093 12.9 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 AAL64801.1 - 0.095 12.9 0.0 3.9 7.8 0.0 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.6 AAL64801.1 - 0.1 12.6 0.0 0.49 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 AAL64801.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region SRP54 PF00448.22 AAL64801.1 - 0.16 11.6 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DLIC PF05783.11 AAL64801.1 - 0.16 10.8 0.1 0.23 10.3 0.1 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) ATPase_2 PF01637.18 AAL64801.1 - 0.16 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 AAL64801.1 - 0.23 10.7 0.1 0.34 10.1 0.1 1.2 1 0 0 1 1 1 0 Zeta toxin AIG1 PF04548.16 AAL64801.1 - 0.25 10.7 0.1 0.37 10.1 0.1 1.3 1 0 0 1 1 1 0 AIG1 family RNA_pol_Rpb6 PF01192.22 AAL64802.1 - 4.9e-13 48.8 0.0 8.6e-13 48.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb6 Cpn60_TCP1 PF00118.24 AAL64803.1 - 3.3e-182 606.5 6.5 3.8e-182 606.3 6.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SHOCT PF09851.9 AAL64803.1 - 0.0076 16.0 0.1 0.025 14.3 0.1 2.0 1 0 0 1 1 1 1 Short C-terminal domain TPP_enzyme_C PF02775.21 AAL64804.1 - 2.7e-23 82.5 0.4 4.2e-23 81.8 0.4 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 AAL64804.1 - 0.0099 15.1 0.1 0.014 14.7 0.1 1.2 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Amidohydro_2 PF04909.14 AAL64804.1 - 0.074 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase E1_dh PF00676.20 AAL64804.1 - 0.15 11.0 1.1 0.25 10.3 1.1 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component LpxK PF02606.14 AAL64804.1 - 0.2 10.7 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase POR_N PF01855.19 AAL64805.1 - 1.1e-67 228.2 0.3 1.5e-67 227.8 0.3 1.1 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg PFOR_II PF17147.4 AAL64805.1 - 2.9e-28 98.2 0.1 5.9e-28 97.2 0.1 1.5 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_C PF02780.20 AAL64805.1 - 9.5e-05 22.3 0.1 0.00027 20.8 0.0 1.7 2 0 0 2 2 2 1 Transketolase, C-terminal domain OxoGdeHyase_C PF16870.5 AAL64805.1 - 0.037 13.7 0.0 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 2-oxoglutarate dehydrogenase C-terminal Fer4 PF00037.27 AAL64806.1 - 8.4e-16 57.0 15.7 6.9e-09 35.2 5.9 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 AAL64806.1 - 4.8e-13 49.5 19.1 1.8e-09 38.1 8.4 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 AAL64806.1 - 3.1e-12 46.4 7.6 3.8e-12 46.2 7.6 1.1 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 AAL64806.1 - 3.4e-12 45.9 13.1 3.3e-06 26.9 4.9 2.1 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 AAL64806.1 - 8.6e-10 38.1 11.4 8.2e-06 25.6 2.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 AAL64806.1 - 1e-09 39.2 6.4 2.4e-05 25.2 1.7 2.1 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 AAL64806.1 - 4.9e-09 36.2 5.5 6.4e-09 35.9 5.5 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAL64806.1 - 3.7e-08 33.3 9.4 0.00012 22.2 2.0 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAL64806.1 - 1.5e-06 28.6 4.9 0.0098 16.4 0.1 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 AAL64806.1 - 1e-05 26.0 8.8 0.00079 19.9 0.4 2.3 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 AAL64806.1 - 0.00015 22.4 12.2 0.19 12.5 0.5 2.9 2 1 0 2 2 2 2 4Fe-4S single cluster domain Fer4_4 PF12800.7 AAL64806.1 - 0.00016 21.9 12.2 0.049 14.1 1.8 2.2 1 1 1 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 AAL64806.1 - 0.0002 21.7 9.7 0.061 13.8 1.0 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_22 PF17179.4 AAL64806.1 - 0.0034 18.2 9.6 0.086 13.7 1.9 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_18 PF13746.6 AAL64806.1 - 0.0077 16.4 8.0 0.027 14.7 8.0 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_3 PF12798.7 AAL64806.1 - 0.03 15.2 16.2 0.08 13.9 6.0 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain ETF_QO PF05187.13 AAL64806.1 - 1.5 9.0 5.7 1.9 8.7 0.7 2.0 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S POR PF01558.18 AAL64807.1 - 2.3e-29 102.7 1.5 5.7e-29 101.4 1.5 1.5 1 1 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase UDPG_MGDP_dh_N PF03721.14 AAL64808.1 - 4e-41 140.7 1.8 6.8e-41 139.9 1.0 1.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 AAL64808.1 - 5.8e-27 94.2 0.0 1.3e-26 93.1 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 AAL64808.1 - 7.2e-22 77.4 0.0 1.9e-21 76.1 0.0 1.8 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain F420_oxidored PF03807.17 AAL64808.1 - 1e-05 26.0 8.1 0.015 15.9 0.1 4.2 3 1 1 4 4 4 2 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 AAL64808.1 - 6.7e-05 23.1 2.8 0.0011 19.2 1.0 3.1 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 AAL64808.1 - 7.3e-05 22.2 0.4 0.083 12.3 0.1 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 AAL64808.1 - 0.0013 18.9 3.6 0.1 12.9 0.3 3.4 3 0 0 3 3 3 1 TrkA-N domain 3HCDH_N PF02737.18 AAL64808.1 - 0.0032 17.4 2.1 0.0035 17.3 0.8 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Urocanase PF01175.18 AAL64808.1 - 0.0033 17.1 0.9 0.007 16.0 0.9 1.5 1 0 0 1 1 1 1 Urocanase Rossmann-like domain NAD_Gly3P_dh_N PF01210.23 AAL64808.1 - 0.0037 17.3 1.9 2.2 8.3 0.0 2.4 2 0 0 2 2 2 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ThiF PF00899.21 AAL64808.1 - 0.024 14.0 0.8 0.04 13.3 0.8 1.3 1 0 0 1 1 1 0 ThiF family DpaA_N PF16924.5 AAL64808.1 - 0.075 13.1 1.0 5.3 7.2 0.1 3.2 4 0 0 4 4 4 0 Dipicolinate synthase subunit A N-terminal domain DUF4369 PF14289.6 AAL64808.1 - 0.15 12.6 0.2 0.36 11.4 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4369) Lactamase_B_2 PF12706.7 AAL64809.1 - 5.4e-22 78.3 0.4 6.3e-22 78.1 0.4 1.0 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 AAL64809.1 - 0.00016 21.7 0.5 0.00029 20.9 0.5 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 AAL64809.1 - 0.0081 15.6 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 AAL64809.1 - 0.1 12.5 0.1 0.18 11.7 0.1 1.6 1 1 0 1 1 1 0 Beta-lactamase superfamily domain DUF359 PF04019.12 AAL64810.1 - 3.8e-29 100.9 0.0 4.5e-29 100.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF359) Thioredoxin_4 PF13462.6 AAL64811.1 - 8.5e-19 68.3 0.0 1.1e-18 67.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 AAL64811.1 - 0.00014 21.8 0.7 0.069 12.9 0.0 2.4 1 1 1 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 AAL64811.1 - 0.12 12.8 0.0 0.85 10.1 0.0 2.1 1 1 0 1 1 1 0 Thioredoxin-like domain eRF1_1 PF03463.15 AAL64813.1 - 7.3e-20 71.3 0.1 1.2e-19 70.6 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 AAL64813.1 - 3.5e-09 37.1 3.3 4.8e-08 33.5 0.3 3.2 3 1 0 3 3 3 1 eRF1 domain 3 MMR_HSR1 PF01926.23 AAL64815.1 - 4.1e-07 30.1 0.0 5e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 AAL64815.1 - 6.2e-07 29.2 1.1 3.9e-06 26.6 1.1 1.9 1 1 0 1 1 1 1 Ras family Arf PF00025.21 AAL64815.1 - 7e-06 25.6 0.0 9.1e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.9 AAL64815.1 - 0.022 14.5 0.2 0.1 12.3 0.2 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 AAL64815.1 - 0.026 14.1 0.2 0.5 9.9 0.2 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_24 PF13479.6 AAL64815.1 - 0.037 13.7 0.0 0.039 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 AAL64815.1 - 0.049 12.8 0.1 0.073 12.2 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain Roc PF08477.13 AAL64815.1 - 0.051 13.8 0.2 0.4 10.9 0.2 2.1 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 AAL64815.1 - 0.085 13.0 0.2 0.085 13.0 0.2 1.3 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 AAL64815.1 - 0.17 12.3 0.1 0.4 11.1 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 AAL64816.1 - 8e-47 159.3 0.2 9.2e-47 159.1 0.2 1.0 1 0 0 1 1 1 1 NTPase DUF2478 PF10649.9 AAL64816.1 - 1.8e-06 27.6 0.2 2.8e-06 27.0 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2478) AAA_18 PF13238.6 AAL64816.1 - 4.2e-05 24.1 0.0 0.00014 22.4 0.0 1.8 1 1 1 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 AAL64816.1 - 0.00029 20.9 0.1 0.00045 20.3 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase MeaB PF03308.16 AAL64816.1 - 0.00069 18.7 0.5 0.00093 18.3 0.5 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 AAL64816.1 - 0.0013 18.5 0.1 0.002 17.8 0.1 1.4 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 AAL64816.1 - 0.0024 17.1 0.4 0.0031 16.8 0.3 1.3 1 1 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 AAL64816.1 - 0.0028 18.1 0.2 0.007 16.8 0.1 1.6 1 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 AAL64816.1 - 0.0037 17.7 0.1 0.007 16.8 0.1 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 AAL64816.1 - 0.012 15.4 0.3 0.06 13.1 0.3 2.0 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DnaB_C PF03796.15 AAL64816.1 - 0.014 14.7 0.0 0.14 11.5 0.0 2.1 2 1 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_24 PF13479.6 AAL64816.1 - 0.017 14.9 0.0 0.026 14.3 0.0 1.3 1 1 0 1 1 1 0 AAA domain KdpD PF02702.17 AAL64816.1 - 0.017 14.6 0.2 0.072 12.6 0.2 1.9 1 1 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain NACHT PF05729.12 AAL64816.1 - 0.018 15.0 0.1 0.028 14.3 0.1 1.3 1 0 0 1 1 1 0 NACHT domain SRP54 PF00448.22 AAL64816.1 - 0.024 14.3 0.2 0.062 12.9 0.2 1.8 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 AAL64816.1 - 0.026 14.8 0.1 0.053 13.8 0.1 1.6 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 AAL64816.1 - 0.034 13.7 0.1 0.081 12.4 0.1 1.7 2 1 0 2 2 2 0 Ferrous iron transport protein B AAA_28 PF13521.6 AAL64816.1 - 0.034 14.4 0.1 0.052 13.8 0.1 1.6 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 AAL64816.1 - 0.048 13.2 0.1 0.067 12.8 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 AAL64816.1 - 0.07 12.9 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein CbiA PF01656.23 AAL64816.1 - 0.11 12.5 0.2 0.23 11.5 0.2 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain RuvB_N PF05496.12 AAL64816.1 - 0.14 11.9 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_17 PF13207.6 AAL64816.1 - 0.14 12.6 0.1 0.26 11.7 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 AAL64816.1 - 0.16 11.7 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain polyprenyl_synt PF00348.17 AAL64817.1 - 2e-33 115.5 0.0 3e-33 115.0 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase HTH_11 PF08279.12 AAL64818.1 - 3.4e-05 23.7 0.1 3.6e-05 23.6 0.1 1.1 1 0 0 1 1 1 1 HTH domain AbiEi_4 PF13338.6 AAL64818.1 - 0.00058 19.9 0.1 0.00062 19.9 0.1 1.2 1 0 0 1 1 1 1 Transcriptional regulator, AbiEi antitoxin TrmB PF01978.19 AAL64818.1 - 0.00061 19.6 1.5 0.0011 18.8 1.5 1.4 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB FaeA PF04703.12 AAL64818.1 - 0.0013 19.0 0.3 0.0017 18.7 0.3 1.1 1 0 0 1 1 1 1 FaeA-like protein MarR_2 PF12802.7 AAL64818.1 - 0.0015 18.4 0.0 0.002 18.0 0.0 1.1 1 0 0 1 1 1 1 MarR family RuvB_C PF05491.13 AAL64818.1 - 0.0048 16.7 0.1 0.005 16.7 0.1 1.1 1 0 0 1 1 1 1 RuvB C-terminal winged helix domain PaaX PF07848.12 AAL64818.1 - 0.0075 16.5 0.1 0.0081 16.4 0.1 1.2 1 0 0 1 1 1 1 PaaX-like protein DUF4423 PF14394.6 AAL64818.1 - 0.0089 15.8 0.3 0.0098 15.6 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) LexA_DNA_bind PF01726.16 AAL64818.1 - 0.0096 15.7 0.1 0.01 15.6 0.1 1.1 1 0 0 1 1 1 1 LexA DNA binding domain Rrf2 PF02082.20 AAL64818.1 - 0.01 16.1 0.1 0.013 15.9 0.1 1.1 1 0 0 1 1 1 0 Transcriptional regulator Sigma70_r3 PF04539.16 AAL64818.1 - 0.017 15.2 0.1 0.025 14.7 0.1 1.3 1 1 0 1 1 1 0 Sigma-70 region 3 DUF2582 PF10771.9 AAL64818.1 - 0.017 15.2 0.2 0.022 14.9 0.2 1.1 1 0 0 1 1 1 0 Winged helix-turn-helix domain (DUF2582) GntR PF00392.21 AAL64818.1 - 0.021 14.5 0.9 0.03 14.0 0.9 1.3 1 1 0 1 1 1 0 Bacterial regulatory proteins, gntR family DUF1495 PF07381.11 AAL64818.1 - 0.022 14.6 0.0 0.03 14.2 0.0 1.3 1 1 0 1 1 1 0 Winged helix DNA-binding domain (DUF1495) HTH_20 PF12840.7 AAL64818.1 - 0.022 14.8 0.0 0.025 14.6 0.0 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain z-alpha PF02295.17 AAL64818.1 - 0.022 14.8 0.2 0.024 14.6 0.2 1.1 1 0 0 1 1 1 0 Adenosine deaminase z-alpha domain ANAPC2 PF08672.11 AAL64818.1 - 0.055 14.0 0.0 0.093 13.2 0.0 1.4 1 1 0 1 1 1 0 Anaphase promoting complex (APC) subunit 2 DsrD PF08679.11 AAL64818.1 - 0.073 13.3 0.7 0.092 13.0 0.7 1.1 1 0 0 1 1 1 0 Dissimilatory sulfite reductase D (DsrD) DUF3253 PF11625.8 AAL64818.1 - 0.073 13.3 0.2 0.1 12.8 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3253) TFIIE_beta PF02186.15 AAL64818.1 - 0.091 13.1 0.1 0.11 12.8 0.1 1.1 1 0 0 1 1 1 0 TFIIE beta subunit core domain FeoC PF09012.10 AAL64818.1 - 0.12 12.5 0.1 0.13 12.3 0.1 1.1 1 0 0 1 1 1 0 FeoC like transcriptional regulator MarR PF01047.22 AAL64818.1 - 0.12 12.3 0.1 0.16 12.0 0.1 1.2 1 0 0 1 1 1 0 MarR family HTH_24 PF13412.6 AAL64818.1 - 0.13 11.8 0.2 1.4 8.5 0.2 2.0 1 1 0 1 1 1 0 Winged helix-turn-helix DNA-binding DMRL_synthase PF00885.19 AAL64819.1 - 6.5e-34 116.8 3.6 7.3e-34 116.6 3.6 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase Usp PF00582.26 AAL64819.1 - 0.18 12.3 4.4 0.4 11.2 0.3 2.1 2 0 0 2 2 2 0 Universal stress protein family Aminotran_4 PF01063.19 AAL64820.1 - 2.7e-51 174.6 0.0 3.2e-51 174.3 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV IlvN PF07991.12 AAL64821.1 - 3.5e-76 254.4 0.1 6.2e-76 253.6 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 AAL64821.1 - 1.5e-56 190.7 0.6 2e-56 190.3 0.6 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.17 AAL64821.1 - 7.7e-09 36.0 0.0 1.9e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 AAL64821.1 - 2.9e-07 30.8 0.1 1.1e-06 28.9 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 AAL64821.1 - 1.1e-06 28.1 0.1 3.3e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 AAL64821.1 - 0.00011 22.3 0.0 0.00053 20.1 0.0 1.9 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ApbA PF02558.16 AAL64821.1 - 0.011 15.4 1.0 0.087 12.5 1.0 2.4 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 AAL64821.1 - 0.021 14.9 0.0 0.055 13.5 0.0 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 AAL64821.1 - 0.12 11.6 0.3 0.37 10.0 0.3 1.7 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ACT_5 PF13710.6 AAL64822.1 - 6.3e-15 54.8 0.0 7.6e-15 54.5 0.0 1.1 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 AAL64822.1 - 0.011 16.3 0.1 0.013 16.1 0.1 1.1 1 0 0 1 1 1 0 ACT domain TPP_enzyme_N PF02776.18 AAL64823.1 - 2.1e-48 164.2 0.0 3.4e-47 160.2 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 AAL64823.1 - 8.9e-44 148.6 0.0 5.2e-42 142.8 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 AAL64823.1 - 1.1e-41 142.1 0.0 1e-40 139.0 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain POR_N PF01855.19 AAL64823.1 - 0.005 16.6 0.5 0.015 15.1 0.4 1.8 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg NUDIX PF00293.28 AAL64824.1 - 6.8e-13 48.8 0.2 1e-12 48.2 0.2 1.2 1 0 0 1 1 1 1 NUDIX domain Gemini_AL1 PF00799.20 AAL64825.1 - 0.052 13.9 0.4 0.066 13.6 0.4 1.2 1 0 0 1 1 1 0 Geminivirus Rep catalytic domain Beta-Casp PF10996.8 AAL64827.1 - 2.9e-14 53.3 0.0 6.7e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 AAL64827.1 - 3.2e-14 52.6 0.0 6.8e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_6 PF16661.5 AAL64827.1 - 9.8e-14 51.2 0.0 1.6e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 AAL64827.1 - 1e-09 38.7 0.9 1.3e-08 35.1 0.8 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AAL64827.1 - 1.4e-09 37.7 0.0 2.5e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Ribosomal_L26 PF16906.5 AAL64828.1 - 1.5e-30 105.5 0.6 1.8e-30 105.2 0.6 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 AAL64828.1 - 2.2e-10 40.1 7.3 2.3e-10 40.0 3.9 2.1 2 0 0 2 2 2 1 KOW motif Ribosomal_S4e PF00900.20 AAL64829.1 - 2.5e-23 81.8 0.1 4.4e-23 81.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.12 AAL64829.1 - 2.5e-11 43.5 5.0 2.5e-11 43.5 5.0 2.0 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.25 AAL64829.1 - 1.3e-10 40.8 0.6 8.3e-10 38.2 0.1 2.3 2 0 0 2 2 2 1 S4 domain LDcluster4 PF18306.1 AAL64829.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 SLOG cluster4 family ABC_tran PF00005.27 AAL64831.1 - 2e-31 109.3 0.0 2.6e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 AAL64831.1 - 1.8e-19 70.0 0.2 3.2e-19 69.2 0.2 1.4 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 AAL64831.1 - 3.6e-06 27.0 0.2 0.29 10.9 0.0 3.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 AAL64831.1 - 1e-05 25.8 0.1 8.1e-05 22.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAL64831.1 - 0.00049 20.5 0.0 0.00082 19.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AAL64831.1 - 0.0073 16.0 0.2 0.013 15.2 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 AAL64831.1 - 0.016 14.9 0.2 0.073 12.8 0.1 1.8 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 AAL64831.1 - 0.026 14.0 0.0 2.4 7.5 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_13 PF13166.6 AAL64831.1 - 0.027 13.1 0.1 0.27 9.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 AAL64831.1 - 0.028 13.8 0.4 0.63 9.3 0.1 2.1 2 0 0 2 2 2 0 KaiC AAA_33 PF13671.6 AAL64831.1 - 0.034 14.3 0.1 0.17 12.0 0.1 2.0 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 AAL64831.1 - 0.13 12.2 0.2 0.21 11.5 0.2 1.3 1 0 0 1 1 1 0 NACHT domain MobB PF03205.14 AAL64831.1 - 0.22 11.4 0.2 0.35 10.8 0.2 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.17 AAL64831.1 - 0.24 11.1 0.1 1.3 8.8 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.6 AAL64831.1 - 0.28 10.9 0.2 0.44 10.2 0.2 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 AAL64831.1 - 0.29 10.3 0.2 0.46 9.6 0.2 1.2 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 AAL64832.1 - 1.6e-26 93.4 0.0 2.5e-26 92.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 AAL64832.1 - 4.1e-18 65.6 0.2 6.8e-18 64.9 0.2 1.4 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 AAL64832.1 - 8.1e-06 25.8 0.9 3.8e-05 23.6 0.0 2.0 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAL64832.1 - 2.2e-05 24.0 1.2 0.00032 20.2 0.3 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.17 AAL64832.1 - 0.0002 21.2 0.1 0.036 13.8 0.0 2.2 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_22 PF13401.6 AAL64832.1 - 0.0027 18.0 0.3 0.077 13.3 0.3 2.2 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AAL64832.1 - 0.0029 17.6 0.1 0.0062 16.4 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase TniB PF05621.11 AAL64832.1 - 0.0034 16.8 0.1 0.04 13.3 0.1 2.1 2 0 0 2 2 2 1 Bacterial TniB protein AAA_5 PF07728.14 AAL64832.1 - 0.051 13.6 0.0 0.24 11.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 AAL64832.1 - 0.078 12.7 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.6 AAL64832.1 - 0.11 12.8 0.3 0.37 11.1 0.0 2.1 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit PfkB PF00294.24 AAL64833.1 - 6.9e-11 42.0 0.0 7.4e-10 38.6 0.0 2.0 2 0 0 2 2 2 1 pfkB family carbohydrate kinase Carb_kinase PF01256.17 AAL64833.1 - 0.035 13.6 0.0 0.19 11.2 0.0 1.9 2 0 0 2 2 2 0 Carbohydrate kinase HrcA_DNA-bdg PF03444.15 AAL64834.1 - 9.5e-32 108.5 0.0 1.9e-31 107.6 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix transcription repressor, HrcA DNA-binding CBS PF00571.28 AAL64834.1 - 3e-27 94.8 5.6 1.2e-15 57.7 1.0 3.6 3 0 0 3 3 3 2 CBS domain Rrf2 PF02082.20 AAL64834.1 - 1.1e-10 41.7 0.1 2.4e-10 40.6 0.1 1.6 1 0 0 1 1 1 1 Transcriptional regulator Fe_dep_repress PF01325.19 AAL64834.1 - 2.3e-05 24.5 0.1 4.1e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_11 PF08279.12 AAL64834.1 - 0.00027 20.8 0.6 0.00069 19.5 0.0 2.1 2 0 0 2 2 2 1 HTH domain HTH_5 PF01022.20 AAL64834.1 - 0.0015 18.3 0.1 0.017 15.0 0.0 2.5 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family DUF4423 PF14394.6 AAL64834.1 - 0.0038 17.0 0.0 0.0077 16.0 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4423) TrmB PF01978.19 AAL64834.1 - 0.0044 16.9 1.8 0.2 11.6 0.2 3.0 2 1 1 3 3 3 1 Sugar-specific transcriptional regulator TrmB Rio2_N PF09202.11 AAL64834.1 - 0.0046 17.1 0.0 0.0089 16.2 0.0 1.5 1 0 0 1 1 1 1 Rio2, N-terminal MarR_2 PF12802.7 AAL64834.1 - 0.011 15.7 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 MarR family Phage_terminase PF10668.9 AAL64834.1 - 0.012 15.6 0.0 0.024 14.7 0.0 1.4 1 0 0 1 1 1 0 Phage terminase small subunit MarR PF01047.22 AAL64834.1 - 0.02 14.8 0.0 0.05 13.5 0.0 1.7 1 0 0 1 1 1 0 MarR family FeoC PF09012.10 AAL64834.1 - 0.084 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 FeoC like transcriptional regulator 2-Hacid_dh_C PF02826.19 AAL64835.1 - 5.1e-56 188.8 0.0 8.7e-56 188.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 AAL64835.1 - 5.9e-29 100.4 0.0 6.6e-29 100.3 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 AAL64835.1 - 9.8e-06 25.7 0.0 2.1e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 AAL64835.1 - 0.00013 21.5 0.1 0.00049 19.7 0.0 1.8 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_2 PF03446.15 AAL64835.1 - 0.0028 17.8 0.1 0.0063 16.7 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.21 AAL64835.1 - 0.0064 15.8 0.7 0.014 14.7 0.2 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Gp_dh_N PF00044.24 AAL64835.1 - 0.025 14.9 0.2 0.055 13.8 0.2 1.6 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain F420_oxidored PF03807.17 AAL64835.1 - 0.035 14.7 0.8 0.12 13.0 0.0 2.3 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent XdhC_C PF13478.6 AAL64835.1 - 0.13 12.7 0.1 0.45 11.0 0.0 1.9 2 0 0 2 2 2 0 XdhC Rossmann domain Aminotran_5 PF00266.19 AAL64836.1 - 3e-23 82.4 0.0 3.7e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 AAL64836.1 - 1.1e-05 24.9 0.0 0.00011 21.5 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 AAL64836.1 - 8.8e-05 21.2 0.0 0.00012 20.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SHMT PF00464.19 AAL64836.1 - 0.0089 14.7 0.0 0.014 14.1 0.0 1.4 1 1 0 1 1 1 1 Serine hydroxymethyltransferase DUF89 PF01937.19 AAL64837.1 - 2.8e-18 66.0 0.2 1.3e-15 57.2 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function DUF89 OmpH PF03938.14 AAL64838.1 - 0.0081 16.5 0.4 0.024 15.0 0.4 1.6 1 1 0 1 1 1 1 Outer membrane protein (OmpH-like) DUF4200 PF13863.6 AAL64838.1 - 0.02 15.3 0.6 0.034 14.6 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) MscS_porin PF12795.7 AAL64838.1 - 0.045 13.3 0.6 0.063 12.8 0.6 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Interferon PF00143.19 AAL64838.1 - 0.057 13.6 0.6 0.099 12.8 0.2 1.6 2 0 0 2 2 2 0 Interferon alpha/beta domain Fez1 PF06818.15 AAL64838.1 - 0.074 13.5 0.4 0.081 13.4 0.4 1.3 1 1 0 1 1 1 0 Fez1 DUF4298 PF14131.6 AAL64838.1 - 0.084 12.8 1.6 0.45 10.5 0.1 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4298) Sec8_exocyst PF04048.14 AAL64838.1 - 0.11 12.4 1.7 4.5 7.2 0.1 2.1 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF2203 PF09969.9 AAL64838.1 - 0.11 13.2 0.2 0.24 12.1 0.2 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Prefoldin PF02996.17 AAL64838.1 - 0.13 12.2 1.5 2.1 8.2 0.4 2.6 2 1 1 3 3 3 0 Prefoldin subunit TACC_C PF05010.14 AAL64838.1 - 0.13 12.0 1.3 0.45 10.3 0.4 1.9 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal ZapD PF07072.11 AAL64838.1 - 0.13 12.0 0.4 1.8 8.3 0.3 2.0 2 0 0 2 2 2 0 Cell division protein Sec2p PF06428.11 AAL64838.1 - 0.25 11.3 2.6 0.31 11.0 1.1 1.8 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p ZapB PF06005.12 AAL64838.1 - 0.62 10.6 4.3 1.8 9.1 0.6 2.2 2 0 0 2 2 2 0 Cell division protein ZapB COMP PF11598.8 AAL64838.1 - 0.63 10.6 2.1 15 6.1 0.1 2.4 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein tRNA_NucTransf2 PF09249.11 AAL64839.1 - 4.4e-43 146.1 0.0 8.4e-43 145.2 0.0 1.5 1 0 0 1 1 1 1 tRNA nucleotidyltransferase, second domain NTP_transf_2 PF01909.23 AAL64839.1 - 1.5e-12 47.6 0.0 3.7e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain SMODS PF18144.1 AAL64839.1 - 0.0002 21.6 0.0 0.00032 20.9 0.0 1.3 1 0 0 1 1 1 1 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain Polbeta PF18765.1 AAL64839.1 - 0.025 14.7 0.0 0.058 13.5 0.0 1.7 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase LigT_PEase PF02834.16 AAL64840.1 - 4.3e-33 113.4 0.3 1.7e-18 66.6 0.0 2.2 2 0 0 2 2 2 2 LigT like Phosphoesterase AKAP7_NLS PF10469.9 AAL64840.1 - 1.6e-16 60.9 0.0 2.4e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 AAL64840.1 - 4.2e-15 56.0 0.0 5.5e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily HVSL PF09749.9 AAL64840.1 - 0.021 14.3 0.0 0.026 14.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein Corona_NS2A PF05213.12 AAL64840.1 - 0.14 11.4 0.1 0.36 10.1 0.1 1.6 1 1 0 1 1 1 0 Coronavirus NS2A protein MarR PF01047.22 AAL64841.1 - 1.1e-06 28.5 0.1 2.5e-06 27.3 0.0 1.7 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 AAL64841.1 - 0.00011 22.6 0.0 0.00016 22.1 0.0 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain B-block_TFIIIC PF04182.12 AAL64841.1 - 0.0085 16.2 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC DUF2250 PF10007.9 AAL64841.1 - 0.015 15.4 0.0 0.024 14.7 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) MarR_2 PF12802.7 AAL64841.1 - 0.033 14.1 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 MarR family PadR PF03551.14 AAL64841.1 - 0.067 13.2 0.1 0.14 12.1 0.1 1.5 1 1 0 1 1 1 0 Transcriptional regulator PadR-like family PDDEXK_1 PF12705.7 AAL64841.1 - 0.14 12.0 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily TF_Zn_Ribbon PF08271.12 AAL64842.1 - 4.2e-15 55.0 0.3 6.9e-15 54.3 0.3 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding TFIIB PF00382.19 AAL64842.1 - 4.9e-09 36.1 0.5 2.3e-07 30.8 0.1 2.4 2 0 0 2 2 2 1 Transcription factor TFIIB repeat zf-ribbon_3 PF13248.6 AAL64842.1 - 0.0024 17.2 3.1 0.032 13.6 3.1 2.2 1 1 0 1 1 1 1 zinc-ribbon domain Zn-ribbon_8 PF09723.10 AAL64842.1 - 0.0044 17.1 0.3 0.0085 16.2 0.3 1.4 1 0 0 1 1 1 1 Zinc ribbon domain zf-RRN7 PF11781.8 AAL64842.1 - 0.01 15.5 1.1 0.018 14.7 1.1 1.3 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 TetR_N PF00440.23 AAL64842.1 - 0.023 14.5 0.3 0.16 11.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family Lar_restr_allev PF14354.6 AAL64842.1 - 0.025 14.9 0.3 0.052 13.9 0.3 1.5 1 0 0 1 1 1 0 Restriction alleviation protein Lar Sigma70_r4 PF04545.16 AAL64842.1 - 0.072 12.6 0.0 0.65 9.6 0.0 2.3 2 0 0 2 2 2 0 Sigma-70, region 4 OrfB_Zn_ribbon PF07282.11 AAL64842.1 - 0.083 12.8 0.2 0.22 11.4 0.2 1.7 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Elf1 PF05129.13 AAL64842.1 - 0.15 12.1 0.2 0.44 10.6 0.1 1.8 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Ribosomal_S27e PF01667.17 AAL64842.1 - 0.17 11.6 0.5 0.3 10.8 0.5 1.3 1 0 0 1 1 1 0 Ribosomal protein S27 Vps36-NZF-N PF16988.5 AAL64842.1 - 0.18 11.2 0.3 0.92 9.0 0.2 2.0 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Sigma70_r3 PF04539.16 AAL64842.1 - 0.19 11.9 0.7 3.2 7.9 0.1 2.5 2 0 0 2 2 2 0 Sigma-70 region 3 Prim_Zn_Ribbon PF08273.12 AAL64842.1 - 6.8 7.1 5.1 49 4.3 5.1 2.0 1 1 0 1 1 1 0 Zinc-binding domain of primase-helicase Gar1 PF04410.14 AAL64843.1 - 0.00073 19.3 0.1 0.00082 19.2 0.1 1.1 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Ribosomal_S8e PF01201.22 AAL64844.1 - 1.9e-28 99.3 0.8 2.2e-28 99.2 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e SRP19 PF01922.17 AAL64845.1 - 5.3e-17 62.5 0.0 5.8e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 SRP19 protein LacI PF00356.21 AAL64845.1 - 0.039 13.7 0.1 4 7.3 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family RuvA_C PF07499.13 AAL64845.1 - 0.08 13.4 0.1 0.18 12.3 0.0 1.6 2 0 0 2 2 2 0 RuvA, C-terminal domain ATP_bind_1 PF03029.17 AAL64846.1 - 1e-55 189.2 0.0 1.1e-55 189.0 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 AAL64846.1 - 1.1e-07 31.6 0.0 9.8e-07 28.5 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 AAL64846.1 - 6.2e-06 26.3 0.2 0.00017 21.7 0.2 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase MeaB PF03308.16 AAL64846.1 - 6.3e-06 25.4 0.0 0.0016 17.5 0.0 2.6 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 AAL64846.1 - 3e-05 24.0 0.4 0.35 10.7 0.0 3.8 3 1 0 3 3 3 2 RsgA GTPase CbiA PF01656.23 AAL64846.1 - 0.00037 20.5 0.0 0.00056 20.0 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain PduV-EutP PF10662.9 AAL64846.1 - 0.00046 20.0 0.4 2.1 8.1 0.0 3.6 3 1 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation ArsA_ATPase PF02374.15 AAL64846.1 - 0.00099 18.4 0.1 0.003 16.8 0.0 1.7 1 1 1 2 2 2 1 Anion-transporting ATPase AAA_16 PF13191.6 AAL64846.1 - 0.0024 18.3 0.0 0.0034 17.8 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain SRP54 PF00448.22 AAL64846.1 - 0.0035 17.0 0.0 0.011 15.3 0.0 1.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain CLP1_P PF16575.5 AAL64846.1 - 0.0064 16.3 0.0 0.22 11.3 0.0 2.3 2 1 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop cobW PF02492.19 AAL64846.1 - 0.0096 15.5 0.3 3.4 7.2 0.1 2.3 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 AAL64846.1 - 0.019 15.1 0.1 0.039 14.1 0.0 1.5 2 0 0 2 2 2 0 Helicase HerA, central domain MobB PF03205.14 AAL64846.1 - 0.028 14.3 0.0 0.081 12.8 0.0 1.8 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.27 AAL64846.1 - 0.033 14.7 0.0 0.043 14.3 0.0 1.6 1 1 0 1 1 1 0 ABC transporter Gtr1_RagA PF04670.12 AAL64846.1 - 0.043 13.2 0.3 0.82 9.0 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region ParA PF10609.9 AAL64846.1 - 0.043 13.3 0.0 0.071 12.5 0.0 1.4 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase AAA_30 PF13604.6 AAL64846.1 - 0.043 13.5 0.0 0.096 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 AAL64846.1 - 0.05 13.4 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 AAL64846.1 - 0.06 13.3 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 NACHT domain MMR_HSR1_Xtn PF16897.5 AAL64846.1 - 0.067 13.2 0.1 3.4 7.7 0.0 2.9 2 1 0 2 2 2 0 C-terminal region of MMR_HSR1 domain NTPase_1 PF03266.15 AAL64846.1 - 0.079 12.9 0.1 12 5.8 0.0 2.9 2 1 1 3 3 3 0 NTPase SRPRB PF09439.10 AAL64846.1 - 0.08 12.4 0.2 7.6 5.9 0.1 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit DUF815 PF05673.13 AAL64846.1 - 0.085 12.0 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 AAL64846.1 - 0.09 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 AAL64846.1 - 0.09 13.0 0.2 1.7 8.9 0.2 2.3 1 1 0 1 1 1 0 AAA domain Roc PF08477.13 AAL64846.1 - 0.12 12.6 0.1 4.1 7.6 0.0 2.3 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase APS_kinase PF01583.20 AAL64846.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_28 PF13521.6 AAL64846.1 - 0.17 12.1 0.0 0.26 11.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain Ribosomal_L21e PF01157.18 AAL64847.1 - 1.5e-31 108.3 0.9 1.6e-31 108.1 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L21e RNA_pol_Rpb4 PF03874.16 AAL64848.1 - 3.4e-11 43.5 2.2 4.1e-11 43.3 2.2 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 DUF1128 PF06569.11 AAL64848.1 - 0.052 13.5 0.1 0.1 12.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) Cnd1 PF12717.7 AAL64848.1 - 0.066 13.2 1.2 0.67 10.0 0.3 2.0 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF655 PF04919.12 AAL64849.1 - 6.5e-52 176.1 1.1 7.5e-52 175.9 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF655) HHH_6 PF14579.6 AAL64849.1 - 3.4e-06 27.2 0.2 1e-05 25.7 0.1 1.9 1 1 1 2 2 2 1 Helix-hairpin-helix motif HHH_3 PF12836.7 AAL64849.1 - 0.002 18.3 0.1 0.004 17.4 0.1 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif eIF-5a PF01287.20 AAL64850.1 - 6.3e-12 45.4 0.3 1.1e-11 44.7 0.3 1.4 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 AAL64850.1 - 6.4e-07 29.3 0.0 1.5e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain EFP PF01132.20 AAL64850.1 - 0.0011 18.9 0.0 0.0025 17.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain Phage_TAC_7 PF10109.9 AAL64850.1 - 0.078 13.1 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Phage tail assembly chaperone proteins, E, or 41 or 14 GTP_EFTU_D2 PF03144.25 AAL64850.1 - 0.099 13.0 0.6 0.69 10.3 0.5 2.4 1 1 1 2 2 2 0 Elongation factor Tu domain 2 PNP_UDP_1 PF01048.20 AAL64851.1 - 1e-38 132.9 0.0 1.1e-38 132.8 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily DUF1064 PF06356.11 AAL64851.1 - 0.16 12.3 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1064) SUI1 PF01253.22 AAL64853.1 - 9.4e-17 61.3 0.1 1.6e-16 60.6 0.1 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 Img2 PF05046.14 AAL64853.1 - 0.025 14.9 0.1 0.03 14.6 0.1 1.5 1 1 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) RE_EcoO109I PF14511.6 AAL64854.1 - 0.04 13.5 0.0 0.054 13.1 0.0 1.2 1 0 0 1 1 1 0 Type II restriction endonuclease EcoO109I Cyanate_lyase PF02560.14 AAL64854.1 - 0.046 13.6 0.0 3.9 7.4 0.0 2.3 1 1 1 2 2 2 0 Cyanate lyase C-terminal domain Hjc PF01870.18 AAL64854.1 - 0.11 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Archaeal holliday junction resolvase (hjc) tRNA-synt_1d PF00750.19 AAL64855.1 - 1.3e-35 123.0 0.5 1.4e-25 90.0 0.1 2.2 1 1 0 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.15 AAL64855.1 - 5.1e-29 100.9 0.5 2.4e-27 95.5 0.0 2.5 2 0 0 2 2 2 1 DALR anticodon binding domain tRNA-synt_1g PF09334.11 AAL64855.1 - 0.0022 16.8 0.2 0.052 12.3 0.1 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 AAL64855.1 - 0.0043 15.4 0.2 0.26 9.5 0.0 2.8 3 0 0 3 3 3 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 AAL64855.1 - 0.0084 15.1 0.4 1.1 8.1 0.0 3.1 2 2 1 3 3 3 1 tRNA synthetases class I (K) tRNA-synt_1e PF01406.19 AAL64855.1 - 0.017 14.5 0.0 0.083 12.2 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain DUF4404 PF14357.6 AAL64855.1 - 0.032 14.9 0.2 0.2 12.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Ribosomal_S28e PF01200.18 AAL64856.1 - 1.4e-29 101.9 4.8 1.5e-29 101.7 4.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Ribosomal_L24e PF01246.20 AAL64857.1 - 7.3e-22 77.4 1.2 7.8e-22 77.3 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L24e zf-FCS PF06467.14 AAL64857.1 - 0.00026 20.9 0.4 0.00036 20.4 0.4 1.3 1 0 0 1 1 1 1 MYM-type Zinc finger with FCS sequence motif VATC PF18716.1 AAL64857.1 - 0.013 15.4 1.5 0.026 14.4 1.5 1.5 1 1 0 1 1 1 0 Vms1-associating treble clef domain Ribosomal_L7Ae PF01248.26 AAL64858.1 - 1.7e-28 98.2 0.6 2.2e-28 97.8 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 AAL64858.1 - 7.3e-06 25.8 0.1 1.1e-05 25.2 0.1 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 AAL64858.1 - 0.0067 16.5 0.0 0.0081 16.2 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 BPD_transp_2 PF02653.16 AAL64859.1 - 6.2e-40 137.1 30.3 8.3e-40 136.6 30.3 1.1 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component BPD_transp_2 PF02653.16 AAL64860.1 - 8.3e-35 120.2 41.9 9.8e-35 120.0 41.9 1.1 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component ResB PF05140.14 AAL64860.1 - 0.33 9.6 0.8 0.49 9.1 0.8 1.2 1 0 0 1 1 1 0 ResB-like family ANF_receptor PF01094.28 AAL64861.1 - 2.3e-55 188.2 0.0 2.8e-55 187.9 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 AAL64861.1 - 2.1e-49 169.0 8.5 2.8e-49 168.6 8.5 1.2 1 0 0 1 1 1 1 Periplasmic binding protein LppC PF04348.13 AAL64861.1 - 5.6e-10 38.6 0.2 8e-10 38.1 0.2 1.2 1 0 0 1 1 1 1 LppC putative lipoprotein Peripla_BP_5 PF13433.6 AAL64861.1 - 5.3e-06 25.7 0.0 2.3e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 Periplasmic binding protein domain ABC_tran PF00005.27 AAL64862.1 - 5.8e-28 98.1 0.0 7.3e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter BCA_ABC_TP_C PF12399.8 AAL64862.1 - 1.2e-07 31.5 0.2 2.3e-07 30.6 0.2 1.5 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_21 PF13304.6 AAL64862.1 - 1.6e-07 31.4 0.1 6.4e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AAL64862.1 - 8.3e-07 29.7 0.0 1.5e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAL64862.1 - 5.1e-06 26.1 0.0 9.1e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 AAL64862.1 - 3.8e-05 23.5 0.4 0.0024 17.6 0.1 2.2 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 AAL64862.1 - 7.1e-05 22.4 0.1 0.0013 18.3 0.0 2.0 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 AAL64862.1 - 0.00012 21.9 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AAL64862.1 - 0.00093 19.1 0.1 0.0037 17.2 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase ATPase_2 PF01637.18 AAL64862.1 - 0.004 17.1 0.1 0.0081 16.1 0.1 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_25 PF13481.6 AAL64862.1 - 0.0045 16.6 1.7 0.071 12.7 0.0 2.5 2 1 0 2 2 2 1 AAA domain cobW PF02492.19 AAL64862.1 - 0.0056 16.3 0.5 0.058 13.0 0.2 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 AAL64862.1 - 0.0059 17.0 0.1 0.0085 16.5 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AAL64862.1 - 0.007 16.6 0.3 0.051 13.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.6 AAL64862.1 - 0.01 14.5 0.0 0.013 14.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 AAL64862.1 - 0.01 15.5 0.2 3.1 7.5 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_33 PF13671.6 AAL64862.1 - 0.022 14.9 0.2 0.22 11.7 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 AAL64862.1 - 0.023 14.7 0.1 0.11 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain DLIC PF05783.11 AAL64862.1 - 0.025 13.4 0.1 0.037 12.9 0.1 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_7 PF12775.7 AAL64862.1 - 0.028 13.9 0.0 0.055 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region T2SSE PF00437.20 AAL64862.1 - 0.029 13.4 0.1 0.048 12.7 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.29 AAL64862.1 - 0.03 14.7 0.4 0.099 13.1 0.4 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 AAL64862.1 - 0.049 12.4 0.3 0.049 12.4 0.3 1.9 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_19 PF13245.6 AAL64862.1 - 0.05 13.9 0.2 0.12 12.7 0.2 1.6 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 AAL64862.1 - 0.054 13.1 0.3 0.1 12.2 0.3 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_27 PF13514.6 AAL64862.1 - 0.062 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 AAL64862.1 - 0.073 13.0 0.2 0.18 11.7 0.2 1.6 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 AAL64862.1 - 0.11 12.8 0.4 0.73 10.1 0.0 2.3 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 AAL64862.1 - 0.11 12.4 1.6 1.9 8.4 0.3 2.3 2 0 0 2 2 2 0 NTPase MMR_HSR1 PF01926.23 AAL64862.1 - 0.12 12.5 0.4 0.27 11.3 0.4 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase Thymidylate_kin PF02223.17 AAL64862.1 - 0.12 12.0 0.2 0.26 11.0 0.1 1.5 2 0 0 2 2 2 0 Thymidylate kinase MobB PF03205.14 AAL64862.1 - 0.13 12.2 0.0 0.32 10.9 0.0 1.7 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF3232 PF11554.8 AAL64862.1 - 0.14 12.6 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3232) AAA_11 PF13086.6 AAL64862.1 - 0.18 11.6 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AAL64862.1 - 0.18 11.5 0.4 0.29 10.8 0.4 1.3 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 AAL64862.1 - 0.2 11.4 0.3 0.38 10.5 0.1 1.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NPCBM_assoc PF10633.9 AAL64863.1 - 1.2e-12 47.8 19.2 1.2e-05 25.5 0.6 7.3 8 1 0 8 8 8 3 NPCBM-associated, NEW3 domain of alpha-galactosidase CARDB PF07705.11 AAL64863.1 - 0.00051 20.3 7.3 0.15 12.3 0.2 4.0 4 0 0 4 4 4 2 CARDB DUF11 PF01345.18 AAL64863.1 - 0.0023 18.2 0.7 0.0023 18.2 0.7 4.0 3 1 0 3 3 3 1 Domain of unknown function DUF11 TMEM154 PF15102.6 AAL64863.1 - 0.097 12.6 0.8 0.16 11.9 0.8 1.3 1 0 0 1 1 1 0 TMEM154 protein family DUF4625 PF15418.6 AAL64863.1 - 0.15 12.3 0.2 90 3.3 0.0 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4625) Big_3 PF07523.12 AAL64863.1 - 0.23 11.8 3.4 0.28 11.5 0.1 2.8 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) DUF3869 PF12985.7 AAL64863.1 - 0.7 10.3 3.4 17 5.8 0.1 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3869) MFS_1 PF07690.16 AAL64864.1 - 1.4e-52 178.8 41.1 1.9e-52 178.3 41.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 AAL64864.1 - 6.5e-13 48.4 21.1 2.7e-12 46.3 7.5 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 AAL64864.1 - 0.00011 21.6 5.9 0.00011 21.6 5.9 3.3 1 1 2 3 3 3 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 AAL64864.1 - 0.0011 17.6 37.3 0.039 12.5 3.1 3.3 3 0 0 3 3 3 3 MFS/sugar transport protein DUF4535 PF15054.6 AAL64864.1 - 0.18 11.5 0.7 0.42 10.4 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4535) Flp_Fap PF04964.14 AAL64864.1 - 0.86 9.5 8.0 0.45 10.4 0.5 4.0 4 0 0 4 4 4 0 Flp/Fap pilin component MFS_3 PF05977.13 AAL64864.1 - 3.2 6.0 17.3 0.022 13.1 3.5 2.3 2 0 0 2 2 2 0 Transmembrane secretion effector MFS_1 PF07690.16 AAL64865.1 - 4.6e-11 42.2 50.2 7.6e-09 34.9 16.8 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF2976 PF11190.8 AAL64865.1 - 0.29 10.9 0.0 0.29 10.9 0.0 3.4 3 2 1 4 4 4 0 Protein of unknown function (DUF2976) Methyltransf_11 PF08241.12 AAL64866.1 - 1.9e-10 41.3 0.0 2.7e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAL64866.1 - 1.7e-08 35.0 0.0 2.3e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAL64866.1 - 7.5e-05 22.6 0.0 9.4e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AAL64866.1 - 0.00032 20.1 0.0 0.00046 19.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 AAL64866.1 - 0.00041 21.0 0.0 0.00053 20.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAL64866.1 - 0.00053 19.9 0.0 0.00055 19.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 AAL64866.1 - 0.069 13.1 0.0 0.088 12.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 AAL64866.1 - 0.25 10.9 0.2 0.38 10.3 0.2 1.4 1 1 0 1 1 1 0 Methyltransferase small domain ATPase PF06745.13 AAL64867.1 - 2.1e-74 249.8 0.0 2.4e-74 249.6 0.0 1.0 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.6 AAL64867.1 - 1.1e-05 25.1 0.0 1.7e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 AAL64867.1 - 0.00074 18.9 0.0 0.0015 17.9 0.0 1.4 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain GvpD PF07088.11 AAL64867.1 - 0.00084 18.1 0.1 0.16 10.6 0.0 2.1 2 0 0 2 2 2 2 GvpD gas vesicle protein Rad51 PF08423.11 AAL64867.1 - 0.002 17.5 0.0 0.0036 16.6 0.0 1.3 1 0 0 1 1 1 1 Rad51 AAA_22 PF13401.6 AAL64867.1 - 0.15 12.3 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 AAL64868.1 - 2.5e-68 229.6 0.7 3.5e-68 229.1 0.7 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 AAL64868.1 - 2.4e-24 85.8 0.0 9.5e-23 80.7 0.0 3.0 3 0 0 3 3 3 1 Signal peptide binding domain SRP54_N PF02881.19 AAL64868.1 - 1.3e-12 47.7 0.5 5.3e-12 45.8 0.0 2.4 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain CbiA PF01656.23 AAL64868.1 - 3.3e-10 40.1 0.0 1.5e-09 37.9 0.0 2.1 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 AAL64868.1 - 2.9e-05 24.3 0.0 0.00026 21.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 AAL64868.1 - 3.7e-05 23.7 0.0 7.2e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_16 PF13191.6 AAL64868.1 - 3.9e-05 24.1 0.1 0.00015 22.2 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain Zeta_toxin PF06414.12 AAL64868.1 - 4e-05 23.0 0.1 0.0001 21.6 0.1 1.6 1 1 0 1 1 1 1 Zeta toxin AAA_31 PF13614.6 AAL64868.1 - 4.4e-05 23.5 1.7 8.8e-05 22.5 0.2 2.2 2 1 0 2 2 1 1 AAA domain AAA_17 PF13207.6 AAL64868.1 - 0.00011 22.7 0.6 0.00081 19.8 0.2 2.4 2 0 0 2 2 2 1 AAA domain ParA PF10609.9 AAL64868.1 - 0.00014 21.4 0.1 0.00043 19.8 0.0 1.8 2 0 0 2 2 1 1 NUBPL iron-transfer P-loop NTPase MobB PF03205.14 AAL64868.1 - 0.0002 21.3 0.2 0.00066 19.6 0.1 1.9 2 0 0 2 2 1 1 Molybdopterin guanine dinucleotide synthesis protein B Thymidylate_kin PF02223.17 AAL64868.1 - 0.0002 21.1 0.4 0.0021 17.8 0.1 2.7 3 0 0 3 3 3 1 Thymidylate kinase cobW PF02492.19 AAL64868.1 - 0.00027 20.6 2.6 0.0027 17.3 2.6 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain KTI12 PF08433.10 AAL64868.1 - 0.00027 20.5 0.0 0.00054 19.5 0.0 1.5 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 AAL64868.1 - 0.00049 20.3 0.0 0.001 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain MipZ PF09140.11 AAL64868.1 - 0.00067 19.0 0.4 0.062 12.6 0.4 2.3 1 1 0 1 1 1 1 ATPase MipZ AAA_24 PF13479.6 AAL64868.1 - 0.00092 19.0 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 AAL64868.1 - 0.0011 19.0 0.1 0.0037 17.3 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 AAL64868.1 - 0.0025 18.1 0.0 0.0053 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain CLP1_P PF16575.5 AAL64868.1 - 0.0034 17.2 0.1 0.082 12.7 0.0 2.3 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_18 PF13238.6 AAL64868.1 - 0.004 17.7 0.0 0.012 16.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AAL64868.1 - 0.0046 16.7 1.6 0.0054 16.5 0.2 1.9 2 0 0 2 2 1 1 AAA domain MeaB PF03308.16 AAL64868.1 - 0.0047 16.0 0.6 0.013 14.5 0.0 1.9 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ResIII PF04851.15 AAL64868.1 - 0.0064 16.5 0.1 0.02 14.9 0.1 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit LytR_C PF13399.6 AAL64868.1 - 0.0072 17.3 0.6 0.039 14.9 0.5 2.5 2 1 0 2 2 1 1 LytR cell envelope-related transcriptional attenuator NACHT PF05729.12 AAL64868.1 - 0.0087 16.0 0.1 0.022 14.7 0.1 1.7 1 0 0 1 1 1 1 NACHT domain PFOR_II PF17147.4 AAL64868.1 - 0.01 16.2 0.1 0.095 13.0 0.0 2.5 1 1 0 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II NTPase_1 PF03266.15 AAL64868.1 - 0.01 15.8 5.4 0.041 13.8 2.1 2.9 2 1 0 2 2 2 0 NTPase AAA PF00004.29 AAL64868.1 - 0.013 15.9 0.9 0.042 14.3 0.4 2.4 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) ArsA_ATPase PF02374.15 AAL64868.1 - 0.013 14.7 1.9 0.04 13.1 0.2 2.5 2 1 0 3 3 3 0 Anion-transporting ATPase IstB_IS21 PF01695.17 AAL64868.1 - 0.014 15.2 0.1 1.2 8.9 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein ATPase PF06745.13 AAL64868.1 - 0.016 14.6 0.1 0.032 13.6 0.1 1.6 1 0 0 1 1 1 0 KaiC DUF1611 PF07755.11 AAL64868.1 - 0.017 14.4 0.2 0.087 12.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1611_C) P-loop domain LpxK PF02606.14 AAL64868.1 - 0.026 13.6 0.3 0.061 12.4 0.1 1.7 2 0 0 2 2 2 0 Tetraacyldisaccharide-1-P 4'-kinase Gtr1_RagA PF04670.12 AAL64868.1 - 0.027 13.8 0.0 0.068 12.5 0.0 1.7 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_14 PF13173.6 AAL64868.1 - 0.029 14.4 0.0 0.064 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 AAL64868.1 - 0.033 14.2 0.0 0.085 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 AAL64868.1 - 0.038 13.7 0.3 6.6 6.5 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 AAL64868.1 - 0.043 13.6 0.0 0.097 12.4 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein 6PF2K PF01591.18 AAL64868.1 - 0.048 13.0 0.0 0.09 12.1 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase G-alpha PF00503.20 AAL64868.1 - 0.062 12.4 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit VirC1 PF07015.11 AAL64868.1 - 0.062 12.6 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 VirC1 protein RNA_helicase PF00910.22 AAL64868.1 - 0.07 13.5 0.0 0.51 10.7 0.0 2.1 1 1 0 1 1 1 0 RNA helicase Transketolase_C PF02780.20 AAL64868.1 - 0.073 13.0 0.0 0.36 10.7 0.0 2.1 1 0 0 1 1 1 0 Transketolase, C-terminal domain AAA_26 PF13500.6 AAL64868.1 - 0.09 12.6 1.6 3.9 7.3 0.3 2.4 2 0 0 2 2 2 0 AAA domain TPP_enzyme_M PF00205.22 AAL64868.1 - 0.091 12.5 0.0 0.29 10.9 0.0 1.9 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain PPDK_N PF01326.19 AAL64868.1 - 0.11 11.8 0.0 0.36 10.0 0.0 1.8 1 0 0 1 1 1 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain Glyco_transf_4 PF13439.6 AAL64868.1 - 0.14 12.1 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase Family 4 TraC PF07820.12 AAL64868.1 - 0.48 10.8 3.3 0.47 10.8 0.1 2.6 3 0 0 3 3 1 0 TraC-like protein Methyltrn_RNA_2 PF04013.12 AAL64869.1 - 0.003 17.3 0.0 0.0038 17.0 0.0 1.1 1 0 0 1 1 1 1 Putative SAM-dependent RNA methyltransferase THUMP PF02926.17 AAL64870.1 - 8.7e-10 38.9 0.3 2.1e-09 37.7 0.3 1.7 1 0 0 1 1 1 1 THUMP domain TrmB PF01978.19 AAL64870.1 - 0.083 12.8 0.2 2.1 8.3 0.0 2.7 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB GATase PF00117.28 AAL64871.1 - 1.1e-34 119.9 0.0 1.6e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 AAL64871.1 - 4.9e-33 113.1 0.3 1.1e-32 112.0 0.1 1.7 2 0 0 2 2 2 1 GMP synthase C terminal domain NAD_synthase PF02540.17 AAL64871.1 - 1.7e-12 47.0 0.0 1.7e-08 33.9 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 AAL64871.1 - 3.2e-09 36.9 0.1 9.5e-08 32.0 0.1 2.7 2 1 0 2 2 2 1 Peptidase C26 tRNA_Me_trans PF03054.16 AAL64871.1 - 1.2e-05 24.3 0.0 0.00072 18.4 0.0 2.2 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.13 AAL64871.1 - 0.00012 21.7 0.0 0.00063 19.3 0.0 2.0 1 1 1 2 2 2 1 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.20 AAL64871.1 - 0.00015 21.6 0.0 0.00031 20.5 0.0 1.6 1 1 0 1 1 1 1 PP-loop family ThiI PF02568.14 AAL64871.1 - 0.0052 16.4 0.0 0.081 12.5 0.0 2.4 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) Arginosuc_synth PF00764.19 AAL64871.1 - 0.012 15.0 0.1 0.025 13.9 0.1 1.6 1 1 0 1 1 1 0 Arginosuccinate synthase Radical_SAM PF04055.21 AAL64871.1 - 0.034 14.5 0.8 1.2 9.5 0.2 2.9 2 1 0 3 3 3 0 Radical SAM superfamily PAPS_reduct PF01507.19 AAL64871.1 - 0.055 13.5 0.1 0.15 12.0 0.1 1.8 1 1 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family G_glu_transpept PF01019.21 AAL64872.1 - 4.5e-61 207.2 0.0 1.2e-58 199.2 0.0 2.3 1 1 0 1 1 1 1 Gamma-glutamyltranspeptidase ThiS PF02597.20 AAL64874.1 - 1.5e-12 48.0 0.0 1.7e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 ThiS family COG2 PF06148.11 AAL64874.1 - 0.0059 16.7 0.0 0.0078 16.3 0.0 1.1 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 TGS PF02824.21 AAL64874.1 - 0.0069 16.4 0.0 0.76 9.9 0.0 2.3 2 0 0 2 2 2 2 TGS domain Lactamase_B PF00753.27 AAL64875.1 - 4.5e-18 66.0 0.7 7.1e-18 65.3 0.7 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AAL64875.1 - 9.6e-05 22.0 0.0 0.00015 21.3 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain SfsA PF03749.13 AAL64876.1 - 1.3e-42 145.0 0.0 1.8e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 Sugar fermentation stimulation protein RE domain SfsA_N PF17746.1 AAL64876.1 - 7.1e-15 54.9 0.1 1.6e-14 53.8 0.1 1.6 1 0 0 1 1 1 1 SfsA N-terminal OB domain NucS PF01939.16 AAL64876.1 - 0.08 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Endonuclease NucS DUF1028 PF06267.12 AAL64877.1 - 2e-70 236.5 0.7 2.7e-70 236.1 0.7 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF1028) PG_binding_2 PF08823.11 AAL64877.1 - 5.8e-29 100.2 1.8 1e-28 99.4 0.4 2.0 2 0 0 2 2 2 1 Putative peptidoglycan binding domain PG_binding_1 PF01471.18 AAL64877.1 - 0.0015 18.7 0.0 0.0039 17.4 0.0 1.7 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Lactamase_B PF00753.27 AAL64878.1 - 1.6e-13 51.1 3.2 1.3e-12 48.1 3.2 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AAL64878.1 - 0.018 14.6 0.1 0.021 14.4 0.1 1.3 1 1 0 1 1 1 0 Beta-lactamase superfamily domain PEP-utilizers_C PF02896.18 AAL64879.1 - 6.4e-78 261.8 0.0 1e-77 261.1 0.0 1.3 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PPDK_N PF01326.19 AAL64879.1 - 5.6e-54 183.6 0.0 5.9e-45 154.0 0.0 2.5 1 1 1 2 2 2 2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 AAL64879.1 - 1.3e-25 88.9 1.0 4.1e-25 87.3 1.0 1.9 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain HTH_20 PF12840.7 AAL64881.1 - 0.00065 19.7 0.0 0.001 19.1 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 AAL64881.1 - 0.00084 19.2 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 AAL64881.1 - 0.0019 17.7 0.0 0.003 17.1 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HK97-gp10_like PF04883.12 AAL64881.1 - 0.16 13.0 0.3 0.21 12.6 0.3 1.4 1 1 0 1 1 1 0 Bacteriophage HK97-gp10, putative tail-component LpxD PF04613.14 AAL64882.1 - 0.085 12.6 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD HTH_27 PF13463.6 AAL64883.1 - 0.0056 17.1 1.1 0.014 15.9 0.6 1.9 1 1 1 2 2 2 1 Winged helix DNA-binding domain DUF2250 PF10007.9 AAL64883.1 - 0.026 14.6 0.5 0.04 14.0 0.5 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) RQC PF09382.10 AAL64883.1 - 0.046 13.5 0.1 0.075 12.8 0.1 1.4 1 1 0 1 1 1 0 RQC domain HTH_24 PF13412.6 AAL64883.1 - 0.057 13.0 0.2 0.21 11.2 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding DUF2703 PF10865.8 AAL64883.1 - 0.085 13.0 1.0 6.3 7.0 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF2703) ClpB_D2-small PF10431.9 AAL64883.1 - 0.24 11.5 2.2 2.2 8.4 0.1 2.1 2 0 0 2 2 2 0 C-terminal, D2-small domain, of ClpB protein CbiA PF01656.23 AAL64884.1 - 3.6e-07 30.3 0.0 5e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 AAL64884.1 - 1e-05 25.5 2.3 5e-05 23.3 2.3 1.9 1 1 0 1 1 1 1 AAA domain ParA PF10609.9 AAL64884.1 - 0.0074 15.8 1.0 0.012 15.0 1.0 1.5 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase AAA_24 PF13479.6 AAL64884.1 - 0.0087 15.8 0.1 0.017 14.9 0.1 1.4 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 AAL64884.1 - 0.1 11.9 0.3 0.29 10.4 0.3 1.8 1 1 0 1 1 1 0 ATPase MipZ AAA_25 PF13481.6 AAL64884.1 - 0.14 11.7 3.6 1.3 8.6 3.6 2.0 1 1 0 1 1 1 0 AAA domain Ribonuc_red_sm PF00268.21 AAL64885.1 - 0.0053 16.2 0.0 0.0066 16.0 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Linker_histone PF00538.19 AAL64885.1 - 0.11 12.9 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 linker histone H1 and H5 family ApoLp-III PF07464.11 AAL64886.1 - 9.9e-06 25.7 0.0 1.5e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) DUF4456 PF14644.6 AAL64886.1 - 0.0017 18.0 0.1 0.0027 17.4 0.1 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4456) DUF948 PF06103.11 AAL64886.1 - 0.0095 16.2 0.5 0.091 13.0 0.5 2.1 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF948) ERp29 PF07749.12 AAL64886.1 - 0.025 15.5 0.7 0.097 13.6 0.2 2.1 1 1 1 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain SOG2 PF10428.9 AAL64886.1 - 0.13 11.4 0.1 0.15 11.2 0.1 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein MLTR_LBD PF17765.1 AAL64886.1 - 0.18 11.9 1.5 14 5.8 0.3 2.2 1 1 1 2 2 2 0 MmyB-like transcription regulator ligand binding domain TBCA PF02970.16 AAL64886.1 - 0.27 11.6 2.9 6.5 7.2 0.8 2.7 1 1 1 2 2 2 0 Tubulin binding cofactor A Mer2 PF09074.10 AAL64886.1 - 1.9 8.2 5.5 2.3 8.0 1.8 2.1 1 1 1 2 2 2 0 Mer2 AAA_16 PF13191.6 AAL64887.1 - 0.00034 21.0 0.0 0.0009 19.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 AAL64887.1 - 0.01 16.0 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 AAL64887.1 - 0.016 14.9 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 AAL64887.1 - 0.025 14.1 0.0 0.1 12.2 0.1 1.9 2 0 0 2 2 2 0 AAA domain DUF2274 PF10038.9 AAL64887.1 - 0.045 14.2 0.0 0.2 12.1 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2274) DAP3 PF10236.9 AAL64887.1 - 0.077 12.2 0.1 0.17 11.0 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 ATPase PF06745.13 AAL64887.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.27 AAL64887.1 - 0.17 12.4 0.0 0.38 11.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter TIP49 PF06068.13 AAL64887.1 - 0.19 10.9 0.2 0.32 10.2 0.2 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain PduV-EutP PF10662.9 AAL64889.1 - 6.5e-08 32.4 0.0 1.3e-07 31.4 0.0 1.5 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 AAL64889.1 - 1e-07 32.0 0.0 1.2e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 AAL64889.1 - 9e-06 25.4 0.1 5.3e-05 22.9 0.1 1.9 1 1 0 1 1 1 1 Ras family Arf PF00025.21 AAL64889.1 - 4e-05 23.2 0.0 5.4e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 AAL64889.1 - 0.0012 19.0 0.0 0.0053 17.0 0.0 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 AAL64889.1 - 0.0019 17.7 0.0 0.0028 17.2 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 AAL64889.1 - 0.0071 16.3 0.1 0.13 12.2 0.1 2.4 2 1 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 AAL64889.1 - 0.01 15.3 0.0 0.012 15.1 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 AAL64889.1 - 0.016 15.3 0.0 0.053 13.6 0.0 1.7 1 1 1 2 2 2 0 Dynamin family Myb_DNA-bind_7 PF15963.5 AAL64889.1 - 0.026 14.4 0.0 0.042 13.7 0.0 1.2 1 0 0 1 1 1 0 Myb DNA-binding like AIG1 PF04548.16 AAL64889.1 - 0.037 13.4 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 AIG1 family SRP54 PF00448.22 AAL64889.1 - 0.041 13.5 0.2 0.48 10.0 0.4 2.0 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.17 AAL64889.1 - 0.07 12.9 1.3 8.8 6.0 0.2 2.3 1 1 0 2 2 2 0 Conserved hypothetical ATP binding protein TrwB_AAD_bind PF10412.9 AAL64889.1 - 0.23 10.3 0.0 1.1 8.1 0.0 1.8 1 1 1 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain 4HBT PF03061.22 AAL64890.1 - 1.5e-17 63.7 2.8 3.6e-08 33.6 0.2 2.3 2 0 0 2 2 2 2 Thioesterase superfamily MaoC_dehydratas PF01575.19 AAL64890.1 - 0.045 13.3 0.3 0.68 9.5 0.0 2.3 2 0 0 2 2 2 0 MaoC like domain PPS_PS PF02006.16 AAL64891.1 - 1.4e-78 262.5 1.5 1.7e-78 262.2 1.5 1.1 1 0 0 1 1 1 1 Phosphopantothenate/pantothenate synthetase DUF5053 PF16476.5 AAL64891.1 - 0.047 13.4 0.0 2.5 7.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5053) RTT107_BRCT_6 PF16771.5 AAL64891.1 - 0.15 12.2 0.0 0.42 10.8 0.0 1.7 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain ACP_PD PF04336.12 AAL64891.1 - 0.2 12.1 0.1 5.7 7.4 0.1 2.6 2 1 0 2 2 2 0 Acyl carrier protein phosphodiesterase GHMP_kinases_N PF00288.26 AAL64892.1 - 0.15 12.3 4.5 0.18 12.0 0.7 2.6 2 1 1 3 3 3 0 GHMP kinases N terminal domain ApbA_C PF08546.11 AAL64893.1 - 9.9e-35 119.5 0.5 1.3e-34 119.1 0.5 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 AAL64893.1 - 1.3e-12 47.6 0.0 5e-12 45.7 0.0 1.9 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Octopine_DH PF02317.17 AAL64893.1 - 0.11 12.5 0.0 3 7.9 0.0 2.2 1 1 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Pantoate_transf PF02548.15 AAL64894.1 - 1.4e-109 365.5 0.1 1.6e-109 365.2 0.1 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 AAL64894.1 - 6.3e-09 35.6 0.2 1.5e-08 34.4 0.2 1.6 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Robl_LC7 PF03259.17 AAL64894.1 - 0.02 14.7 0.0 0.15 11.8 0.1 2.1 2 0 0 2 2 2 0 Roadblock/LC7 domain Peptidase_U32 PF01136.19 AAL64894.1 - 0.81 8.8 2.4 1.4 8.0 0.1 2.5 3 1 0 3 3 3 0 Peptidase family U32 BPD_transp_2 PF02653.16 AAL64895.1 - 5.3e-20 71.7 30.6 4.1e-19 68.8 30.6 2.0 1 1 0 1 1 1 1 Branched-chain amino acid transport system / permease component BPD_transp_2 PF02653.16 AAL64896.1 - 1.4e-25 90.0 32.7 1.4e-25 90.0 32.7 1.5 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component ABC_tran PF00005.27 AAL64897.1 - 3.6e-47 160.3 0.0 4.5e-29 101.7 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 AAL64897.1 - 3.9e-08 33.5 1.3 0.0058 16.5 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AAL64897.1 - 0.0036 17.0 0.1 0.012 15.4 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 AAL64897.1 - 0.0071 15.8 0.1 9.5 5.6 0.0 3.1 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 AAL64897.1 - 0.011 15.6 0.3 0.085 12.8 0.0 2.4 3 0 0 3 3 3 0 RsgA GTPase AAA_15 PF13175.6 AAL64897.1 - 0.078 12.7 0.1 0.47 10.1 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain DUF3879 PF12995.7 AAL64897.1 - 0.097 12.4 0.0 0.71 9.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3879) AAA_23 PF13476.6 AAL64897.1 - 0.12 12.9 0.1 0.21 12.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain MukB PF04310.12 AAL64897.1 - 0.16 11.8 0.0 0.63 9.8 0.0 1.9 2 0 0 2 2 2 0 MukB N-terminal OTCace PF00185.24 AAL64897.1 - 0.21 11.6 0.0 11 6.0 0.0 2.2 2 0 0 2 2 2 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Bmp PF02608.14 AAL64898.1 - 5.1e-35 120.9 0.0 7e-35 120.5 0.0 1.1 1 0 0 1 1 1 1 ABC transporter substrate-binding protein PnrA-like Peripla_BP_6 PF13458.6 AAL64898.1 - 0.00068 19.4 4.0 0.056 13.1 0.0 2.4 3 0 0 3 3 3 2 Periplasmic binding protein UCR_Fe-S_N PF10399.9 AAL64898.1 - 0.53 9.7 5.8 1.4 8.3 5.8 1.7 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal PEPcase_2 PF14010.6 AAL64899.1 - 1.1e-131 439.7 0.0 1.3e-131 439.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase PEPcase PF00311.17 AAL64899.1 - 5.8e-05 21.4 0.0 7.6e-05 21.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase Lactamase_B_2 PF12706.7 AAL64900.1 - 2.5e-08 33.7 0.1 6.1e-08 32.4 0.1 1.5 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 AAL64900.1 - 1.3e-06 28.4 0.0 2.3e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 AAL64900.1 - 4.6e-06 26.8 2.2 8.2e-05 22.7 2.2 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 AAL64900.1 - 0.0081 16.1 0.1 0.067 13.1 0.0 2.3 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain DRMBL PF07522.14 AAL64900.1 - 0.019 15.2 0.0 0.034 14.3 0.0 1.4 1 0 0 1 1 1 0 DNA repair metallo-beta-lactamase PaRep2b PF07775.11 AAL64901.1 - 8.4e-06 24.5 0.3 8.8e-06 24.5 0.3 1.0 1 0 0 1 1 1 1 PaRep2b protein KCNQ_channel PF03520.14 AAL64901.1 - 0.054 13.3 0.0 0.054 13.3 0.0 1.1 1 0 0 1 1 1 0 KCNQ voltage-gated potassium channel ThiI PF02568.14 AAL64902.1 - 2.2e-52 177.5 0.0 3.4e-52 176.9 0.0 1.2 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) THUMP PF02926.17 AAL64902.1 - 2e-19 70.1 0.1 5.6e-19 68.7 0.1 1.8 1 0 0 1 1 1 1 THUMP domain Rhodanese PF00581.20 AAL64902.1 - 1.9e-08 34.8 0.0 2.2e-07 31.3 0.0 2.3 2 0 0 2 2 2 1 Rhodanese-like domain QueC PF06508.13 AAL64902.1 - 0.00057 19.4 0.0 0.54 9.7 0.0 2.4 2 0 0 2 2 2 2 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 AAL64902.1 - 0.094 11.5 0.1 0.16 10.7 0.1 1.3 1 0 0 1 1 1 0 tRNA methyl transferase ATP_bind_3 PF01171.20 AAL64902.1 - 0.15 11.8 0.0 1.2 8.9 0.0 2.1 2 0 0 2 2 2 0 PP-loop family Phosphorylase PF00343.20 AAL64903.1 - 8.2e-13 47.5 0.0 1.3e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate phosphorylase Glycos_transf_1 PF00534.20 AAL64903.1 - 5.8e-10 39.0 0.0 9.1e-09 35.1 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAL64903.1 - 5.2e-05 23.7 0.0 0.00019 21.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Imm51 PF15595.6 AAL64903.1 - 0.11 12.5 0.1 0.3 11.0 0.1 1.7 1 0 0 1 1 1 0 Immunity protein 51 HTH_IclR PF09339.10 AAL64904.1 - 3.4e-09 36.4 0.1 5.3e-09 35.7 0.1 1.2 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_5 PF01022.20 AAL64904.1 - 4.9e-08 32.7 0.0 8.4e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 AAL64904.1 - 5.3e-05 23.0 0.0 7.9e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 MarR family ATPase_2 PF01637.18 AAL64904.1 - 0.00023 21.2 0.0 0.00034 20.6 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea HTH_24 PF13412.6 AAL64904.1 - 0.0023 17.4 0.1 0.0039 16.7 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_47 PF16221.5 AAL64904.1 - 0.0028 17.2 0.1 0.0042 16.6 0.1 1.3 1 0 0 1 1 1 1 winged helix-turn-helix DprA_WH PF17782.1 AAL64904.1 - 0.0085 16.2 0.1 0.015 15.4 0.1 1.3 1 0 0 1 1 1 1 DprA winged helix domain HTH_45 PF14947.6 AAL64904.1 - 0.035 14.1 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix HTH_AsnC-type PF13404.6 AAL64904.1 - 0.062 13.1 0.2 0.1 12.4 0.2 1.3 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_36 PF13730.6 AAL64904.1 - 0.065 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain MarR PF01047.22 AAL64904.1 - 0.097 12.6 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 MarR family AFOR_C PF01314.18 AAL64905.1 - 1.3e-115 386.5 0.0 1.6e-115 386.2 0.0 1.1 1 0 0 1 1 1 1 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 AFOR_N PF02730.15 AAL64905.1 - 9.7e-80 267.1 0.3 1.6e-79 266.4 0.3 1.4 1 0 0 1 1 1 1 Aldehyde ferredoxin oxidoreductase, N-terminal domain Glyco_hydro_57 PF03065.15 AAL64906.1 - 3.3e-68 230.3 0.0 4.5e-68 229.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Glyco_transf_5 PF08323.11 AAL64907.1 - 4.7e-44 150.9 0.0 7.7e-44 150.2 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 AAL64907.1 - 5e-25 88.0 0.0 9.3e-25 87.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAL64907.1 - 2.1e-18 67.1 0.1 5.5e-18 65.7 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAL64907.1 - 4e-13 49.7 6.1 3.2e-12 46.8 3.9 3.1 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AAL64907.1 - 1.3e-09 38.7 2.9 5.7e-09 36.6 2.9 2.1 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 AAL64907.1 - 0.15 12.5 0.0 0.53 10.7 0.0 1.9 1 0 0 1 1 1 0 Glycosyl transferases group 1 NTP_transferase PF00483.23 AAL64908.1 - 9.7e-35 120.3 0.0 1.5e-34 119.7 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 AAL64908.1 - 3.5e-12 45.5 14.8 0.0001 21.9 2.7 4.0 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 AAL64908.1 - 2.2e-06 26.2 0.7 3.2e-06 25.6 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 AAL64908.1 - 1.8e-05 23.9 0.1 0.0082 15.1 0.1 3.0 2 1 0 2 2 2 1 L-fucokinase NTP_transf_3 PF12804.7 AAL64908.1 - 0.0016 18.8 0.0 0.0029 18.0 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 AAL64908.1 - 0.29 10.9 15.6 1.7 8.4 0.6 4.5 2 1 3 5 5 5 0 Hexapeptide repeat of succinyl-transferase Methyltrn_RNA_3 PF02598.17 AAL64909.1 - 5.8e-45 154.0 0.0 7.2e-45 153.7 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase Med19 PF10278.9 AAL64910.1 - 0.31 11.0 10.2 0.31 11.0 10.2 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 UPF0542 PF15086.6 AAL64910.1 - 1 9.4 4.8 1.3 9.0 4.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 PaRep2b PF07775.11 AAL64911.1 - 1.8e-05 23.5 0.1 1.8e-05 23.5 0.1 1.0 1 0 0 1 1 1 1 PaRep2b protein SecY PF00344.20 AAL64912.1 - 8e-54 183.0 18.5 1.2e-53 182.3 18.5 1.3 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 AAL64912.1 - 0.00045 20.0 0.8 0.0013 18.5 0.8 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p Ribosomal_L27A PF00828.19 AAL64913.1 - 2.9e-18 66.8 0.1 2.9e-18 66.8 0.1 1.5 1 1 1 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A ROK PF00480.20 AAL64914.1 - 2.6e-53 181.4 0.0 3.1e-53 181.2 0.0 1.1 1 0 0 1 1 1 1 ROK family FGGY_N PF00370.21 AAL64914.1 - 0.002 17.7 0.0 0.0051 16.4 0.0 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 AAL64914.1 - 0.0039 16.7 0.0 0.004 16.7 0.0 1.3 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family MutL PF13941.6 AAL64914.1 - 0.093 11.3 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 MutL protein Hydant_A_N PF05378.13 AAL64914.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region ELFV_dehydrog PF00208.21 AAL64915.1 - 2.5e-70 237.0 0.2 3.2e-70 236.6 0.2 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 AAL64915.1 - 1.2e-50 170.8 0.0 1.9e-50 170.1 0.0 1.3 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 2-Hacid_dh_C PF02826.19 AAL64915.1 - 0.00032 20.1 0.3 0.00071 19.0 0.3 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 AAL64915.1 - 0.011 15.8 0.2 0.027 14.5 0.1 1.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ApbA PF02558.16 AAL64915.1 - 0.04 13.6 0.3 0.067 12.8 0.3 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA PALP PF00291.25 AAL64915.1 - 0.062 12.7 0.1 0.1 12.0 0.1 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme UDPG_MGDP_dh_N PF03721.14 AAL64915.1 - 0.068 12.7 0.2 0.12 12.0 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GATase_6 PF13522.6 AAL64917.1 - 3.9e-09 36.8 0.0 4.1e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 AAL64917.1 - 0.0058 15.6 0.0 0.0078 15.1 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Gln-synt_C PF00120.24 AAL64918.1 - 1.7e-94 316.7 0.0 2.6e-94 316.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 AAL64918.1 - 1.6e-13 50.2 0.0 3e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Gln-synt_N_2 PF16952.5 AAL64918.1 - 0.04 13.7 0.0 0.1 12.5 0.0 1.6 2 0 0 2 2 2 0 Glutamine synthetase N-terminal domain GXGXG PF01493.19 AAL64919.1 - 2e-22 79.8 16.2 3.4e-22 79.0 16.2 1.3 1 0 0 1 1 1 1 GXGXG motif GATase_6 PF13522.6 AAL64919.1 - 3.2e-10 40.3 0.0 8e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain Glu_synthase PF01645.17 AAL64920.1 - 2.4e-99 332.9 4.0 5.9e-92 308.6 1.3 2.2 2 0 0 2 2 2 2 Conserved region in glutamate synthase Glu_syn_central PF04898.14 AAL64920.1 - 3.2e-11 43.2 0.6 3.9e-05 23.3 0.0 3.2 3 0 0 3 3 3 3 Glutamate synthase central domain FMN_dh PF01070.18 AAL64920.1 - 8.1e-05 21.8 9.1 0.78 8.7 0.6 3.6 3 1 0 3 3 3 3 FMN-dependent dehydrogenase HEPN PF05168.14 AAL64921.1 - 0.00036 20.7 0.2 0.00082 19.5 0.2 1.7 1 1 0 1 1 1 1 HEPN domain PaREP1 PF05942.11 AAL64921.1 - 0.0048 16.8 0.0 0.006 16.5 0.0 1.2 1 0 0 1 1 1 1 Archaeal PaREP1/PaREP8 family SMBP PF16785.5 AAL64921.1 - 0.071 13.3 0.1 0.098 12.9 0.1 1.1 1 0 0 1 1 1 0 Small metal-binding protein Aminotran_5 PF00266.19 AAL64922.1 - 7.6e-26 90.9 0.0 9.3e-26 90.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 AAL64922.1 - 0.0078 15.4 0.0 0.014 14.6 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Glyco_hydro_42C PF08533.10 AAL64923.1 - 0.094 12.4 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Beta-galactosidase C-terminal domain NTP_transf_3 PF12804.7 AAL64926.1 - 1.1e-22 81.1 0.1 1.8e-22 80.4 0.1 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Glyco_hydro_57 PF03065.15 AAL64927.1 - 7e-101 337.7 0.0 9.8e-101 337.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Glucodextran_C PF09985.9 AAL64927.1 - 6.6e-63 212.2 0.0 1.3e-62 211.2 0.0 1.5 1 0 0 1 1 1 1 C-terminal binding-module, SLH-like, of glucodextranase MGC-24 PF05283.11 AAL64927.1 - 0.039 14.4 2.9 0.068 13.6 2.9 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin SBP_bac_8 PF13416.6 AAL64928.1 - 1.8e-43 149.4 2.7 2.5e-43 148.9 2.7 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AAL64928.1 - 1.8e-29 103.7 5.2 2.9e-29 103.0 5.2 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AAL64928.1 - 1.7e-07 30.9 0.1 1.1e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein Gag_spuma PF03276.14 AAL64928.1 - 0.092 11.2 2.1 0.13 10.7 2.1 1.1 1 0 0 1 1 1 0 Spumavirus gag protein DEC-1_N PF04625.13 AAL64928.1 - 0.61 9.0 5.0 1.1 8.2 5.0 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region BPD_transp_1 PF00528.22 AAL64929.1 - 1.4e-13 51.0 19.2 1.4e-13 51.0 19.2 2.5 2 1 1 3 3 3 2 Binding-protein-dependent transport system inner membrane component TM_PBP2_N PF16296.5 AAL64929.1 - 0.017 15.3 2.9 0.036 14.2 2.9 1.6 1 0 0 1 1 1 0 N-terminal of TM subunit in PBP-dependent ABC transporters BPD_transp_1 PF00528.22 AAL64930.1 - 3.1e-15 56.4 17.0 3.1e-15 56.4 17.0 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component MuF_C PF18819.1 AAL64932.1 - 0.17 11.8 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Phage MuF-C-terminal domain Peptidase_M48 PF01435.18 AAL64933.1 - 9.5e-46 156.0 0.1 1.6e-45 155.3 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M48 DUF1345 PF07077.11 AAL64933.1 - 0.027 14.2 0.6 0.027 14.2 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) DUF4013 PF13197.6 AAL64933.1 - 1 9.2 34.5 0.032 14.1 2.5 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF4013) HTHP PF11534.8 AAL64934.1 - 0.098 13.1 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 Hexameric tyrosine-coordinated heme protein (HTHP) PBP_like PF12727.7 AAL64935.1 - 6.4e-55 185.3 0.1 1.9e-54 183.8 0.0 1.8 2 0 0 2 2 2 1 PBP superfamily domain MoeA_N PF03453.17 AAL64935.1 - 1.5e-46 158.0 0.8 2.9e-46 157.1 0.8 1.5 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 AAL64935.1 - 1.7e-27 95.9 0.0 3.5e-27 94.8 0.0 1.6 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_C PF03454.15 AAL64935.1 - 1.6e-17 63.5 0.5 2.1e-16 59.9 0.0 3.0 3 0 0 3 3 3 1 MoeA C-terminal region (domain IV) SBP_bac_11 PF13531.6 AAL64935.1 - 0.00057 19.7 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein Phosphonate-bd PF12974.7 AAL64935.1 - 0.061 12.9 0.0 0.18 11.3 0.0 1.8 2 0 0 2 2 2 0 ABC transporter, phosphonate, periplasmic substrate-binding protein T2SSE PF00437.20 AAL64935.1 - 0.061 12.4 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein MoeA_N PF03453.17 AAL64936.1 - 6.5e-44 149.5 1.2 1.3e-43 148.5 1.2 1.5 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 AAL64936.1 - 1.1e-28 99.7 0.0 1.7e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_C PF03454.15 AAL64936.1 - 4.2e-19 68.5 0.1 4.2e-19 68.5 0.1 3.1 4 0 0 4 4 4 1 MoeA C-terminal region (domain IV) 7TMR-HDED PF07697.11 AAL64936.1 - 0.086 12.9 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 7TM-HD extracellular GATase_6 PF13522.6 AAL64938.1 - 1e-08 35.5 0.0 1.5e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 AAL64938.1 - 8.4e-07 28.2 0.0 1.3e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II DNA_pol_A_exo1 PF01612.20 AAL64938.1 - 0.23 11.2 0.0 0.31 10.7 0.0 1.2 1 0 0 1 1 1 0 3'-5' exonuclease AsnC_trans_reg PF01037.21 AAL64939.1 - 2.6e-17 62.5 0.2 3e-17 62.4 0.2 1.1 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain GYD PF08734.11 AAL64939.1 - 0.00042 20.2 0.0 0.00047 20.1 0.0 1.3 1 0 0 1 1 1 1 GYD domain HMA PF00403.26 AAL64939.1 - 0.073 13.5 0.1 0.22 12.0 0.1 1.8 1 1 1 2 2 2 0 Heavy-metal-associated domain NapD PF03927.13 AAL64939.1 - 0.089 12.9 0.2 0.13 12.3 0.2 1.3 1 0 0 1 1 1 0 NapD protein AsnC_trans_reg PF01037.21 AAL64941.1 - 1.3e-25 89.1 0.0 2e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 AAL64941.1 - 1.5e-13 50.0 1.8 1.9e-13 49.8 0.9 1.7 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 AAL64941.1 - 1.8e-12 46.9 0.1 3e-12 46.1 0.1 1.4 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain TrmB PF01978.19 AAL64941.1 - 0.0013 18.6 0.0 0.0023 17.8 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.12 AAL64941.1 - 0.0017 18.2 0.0 0.0051 16.7 0.0 1.8 2 0 0 2 2 2 1 HTH domain HTH_5 PF01022.20 AAL64941.1 - 0.0047 16.8 0.0 0.0081 16.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HxlR PF01638.17 AAL64941.1 - 0.012 15.5 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 HxlR-like helix-turn-helix HTH_20 PF12840.7 AAL64941.1 - 0.017 15.2 0.0 0.033 14.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_47 PF16221.5 AAL64941.1 - 0.037 13.6 0.0 0.071 12.7 0.0 1.4 1 0 0 1 1 1 0 winged helix-turn-helix MarR PF01047.22 AAL64941.1 - 0.05 13.5 0.1 0.097 12.6 0.1 1.4 1 0 0 1 1 1 0 MarR family Sulfolobus_pRN PF05584.11 AAL64941.1 - 0.1 12.6 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 Sulfolobus plasmid regulatory protein HTH_IclR PF09339.10 AAL64941.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 1 0 IclR helix-turn-helix domain Ribosomal_S3Ae PF01015.18 AAL64942.1 - 6.6e-59 198.9 0.9 8.1e-59 198.6 0.9 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Phage_TAC_5 PF08890.11 AAL64942.1 - 0.028 14.4 0.1 0.06 13.4 0.1 1.5 1 0 0 1 1 1 0 Phage XkdN-like tail assembly chaperone protein, TAC KH_2 PF07650.17 AAL64943.1 - 0.77 9.6 4.6 3.3 7.6 2.7 2.6 2 1 0 2 2 2 0 KH domain RIO1 PF01163.22 AAL64944.1 - 3.9e-45 153.8 0.0 5.2e-45 153.4 0.0 1.1 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 AAL64944.1 - 3.5e-06 27.1 0.2 5.1e-05 23.3 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 AAL64944.1 - 0.0033 16.9 0.0 0.013 14.8 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.14 AAL64944.1 - 0.0065 15.9 0.0 1.4 8.2 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family POR PF01558.18 AAL64945.1 - 9.7e-36 123.5 0.0 1.2e-35 123.2 0.0 1.1 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase TPP_enzyme_C PF02775.21 AAL64946.1 - 4.3e-20 72.1 1.3 1.1e-19 70.8 1.3 1.7 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4 PF00037.27 AAL64946.1 - 5.3e-13 48.2 11.5 9.2e-09 34.8 3.8 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 AAL64946.1 - 2.4e-08 33.7 18.2 5e-07 29.5 3.6 3.0 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_21 PF14697.6 AAL64946.1 - 4.5e-08 33.1 7.3 9.6e-08 32.0 7.3 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAL64946.1 - 6.8e-07 29.0 19.5 2.2e-05 24.3 3.3 2.8 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 AAL64946.1 - 8.9e-07 29.4 8.9 4.7e-05 23.9 9.3 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAL64946.1 - 1.3e-05 25.2 6.1 0.0013 18.8 0.3 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAL64946.1 - 7e-05 23.7 4.6 0.00061 20.7 0.6 2.4 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 AAL64946.1 - 7.9e-05 22.7 19.5 0.0008 19.5 10.0 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_15 PF13459.6 AAL64946.1 - 0.00035 21.2 4.6 0.21 12.4 0.3 2.8 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_13 PF13370.6 AAL64946.1 - 0.00039 20.9 5.8 0.16 12.5 0.9 2.4 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Transketolase_C PF02780.20 AAL64946.1 - 0.0034 17.3 1.9 0.016 15.1 0.3 2.3 2 0 0 2 2 2 1 Transketolase, C-terminal domain Fer4_4 PF12800.7 AAL64946.1 - 0.0088 16.5 11.7 0.16 12.6 1.7 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain TPP_enzyme_N PF02776.18 AAL64946.1 - 0.018 14.7 0.2 0.031 13.9 0.2 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Fer4_17 PF13534.6 AAL64946.1 - 0.052 14.1 10.5 0.27 11.8 1.5 2.4 1 1 3 4 4 4 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 AAL64946.1 - 0.057 14.3 9.8 0.26 12.1 2.4 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 AAL64946.1 - 0.06 13.8 11.9 0.87 10.1 2.7 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 AAL64946.1 - 0.27 12.3 16.4 0.24 12.4 6.0 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain POR_N PF01855.19 AAL64947.1 - 5.8e-13 49.1 0.1 8.6e-13 48.6 0.1 1.2 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg TPP_enzyme_N PF02776.18 AAL64947.1 - 0.019 14.6 0.1 0.02 14.5 0.1 1.2 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Transket_pyr PF02779.24 AAL64947.1 - 0.02 14.5 0.0 0.26 10.9 0.0 2.0 1 1 0 1 1 1 0 Transketolase, pyrimidine binding domain RNA_POL_M_15KD PF02150.16 AAL64948.1 - 3.6e-05 23.6 0.1 7e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 RNA polymerases M/15 Kd subunit zf-TFIIB PF13453.6 AAL64948.1 - 0.00012 21.4 1.8 0.0003 20.0 0.2 2.3 2 1 0 2 2 2 1 Transcription factor zinc-finger zf-NADH-PPase PF09297.11 AAL64948.1 - 0.00065 19.3 0.4 0.0045 16.6 0.4 2.1 1 1 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain DUF2387 PF09526.10 AAL64948.1 - 0.0017 18.5 0.3 0.003 17.7 0.2 1.5 1 1 0 1 1 1 1 Probable metal-binding protein (DUF2387) DZR PF12773.7 AAL64948.1 - 0.0038 17.2 0.0 0.0058 16.6 0.0 1.2 1 0 0 1 1 1 1 Double zinc ribbon FYDLN_acid PF09538.10 AAL64948.1 - 0.014 16.0 1.7 0.019 15.6 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zinc_ribbon_2 PF13240.6 AAL64948.1 - 0.024 14.3 2.1 0.055 13.2 0.3 2.1 2 0 0 2 2 2 0 zinc-ribbon domain PorA PF11271.8 AAL64948.1 - 0.03 13.6 0.1 0.033 13.5 0.1 1.0 1 0 0 1 1 1 0 Porin PorA CpXC PF14353.6 AAL64948.1 - 0.049 13.7 0.3 0.072 13.1 0.3 1.3 1 1 0 1 1 1 0 CpXC protein UPF0547 PF10571.9 AAL64948.1 - 0.064 13.4 0.3 0.56 10.3 0.1 2.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Mu-like_Com PF10122.9 AAL64948.1 - 0.073 12.5 0.2 2.5 7.6 0.0 2.4 2 0 0 2 2 2 0 Mu-like prophage protein Com zf-Mss51 PF13824.6 AAL64948.1 - 0.3 11.2 1.8 0.36 11.0 0.2 2.0 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF1003 PF06210.11 AAL64948.1 - 1.2 9.2 4.0 1.3 9.1 3.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1003) DNase-RNase PF02577.14 AAL64949.1 - 1.6e-33 115.1 0.0 2e-33 114.8 0.0 1.0 1 0 0 1 1 1 1 Bifunctional nuclease Sec5 PF15469.6 AAL64951.1 - 0.045 13.6 0.0 0.077 12.8 0.0 1.4 1 0 0 1 1 1 0 Exocyst complex component Sec5 Ribosomal_S13_N PF08069.12 AAL64952.1 - 3.6e-25 87.8 0.0 5.8e-25 87.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 AAL64952.1 - 7.2e-15 55.0 0.4 1e-14 54.5 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 HTHP PF11534.8 AAL64952.1 - 0.14 12.6 0.0 0.33 11.4 0.0 1.6 2 0 0 2 2 2 0 Hexameric tyrosine-coordinated heme protein (HTHP) CMAS PF02353.20 AAL64953.1 - 1.6e-08 34.2 0.0 2.3e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DOT1 PF08123.13 AAL64953.1 - 1.3e-06 28.0 0.0 1.9e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.6 AAL64953.1 - 5.1e-06 27.1 0.0 8.7e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain HTH_47 PF16221.5 AAL64953.1 - 8.2e-05 22.1 0.0 0.00024 20.6 0.0 1.8 2 0 0 2 2 2 1 winged helix-turn-helix TrmB PF01978.19 AAL64953.1 - 0.00035 20.4 0.2 0.012 15.5 0.3 2.5 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Methyltransf_31 PF13847.6 AAL64953.1 - 0.00049 19.9 0.0 0.00068 19.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 AAL64953.1 - 0.002 17.9 0.0 0.0035 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 AAL64953.1 - 0.019 14.9 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 AAL64953.1 - 0.022 14.2 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase HTH_24 PF13412.6 AAL64953.1 - 0.026 14.1 0.3 0.071 12.7 0.0 1.9 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding RPA_C PF08784.11 AAL64953.1 - 0.044 14.5 0.0 0.078 13.6 0.0 1.3 1 0 0 1 1 1 0 Replication protein A C terminal Methyltransf_32 PF13679.6 AAL64953.1 - 0.059 13.4 0.0 0.081 12.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 AAL64953.1 - 0.07 12.7 0.0 0.096 12.3 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_2 PF00891.18 AAL64953.1 - 0.086 12.1 0.2 0.53 9.5 0.1 2.1 2 1 0 2 2 2 0 O-methyltransferase domain RrnaAD PF00398.20 AAL64953.1 - 0.2 10.7 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DS PF01916.17 AAL64954.1 - 1.5e-87 293.5 0.0 1.7e-87 293.4 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase PUA PF01472.20 AAL64954.1 - 0.07 13.1 0.3 17 5.5 0.0 3.3 2 1 1 3 3 3 0 PUA domain Glycos_transf_4 PF00953.21 AAL64955.1 - 2.9e-25 89.1 15.6 2.9e-25 89.1 15.6 2.3 3 0 0 3 3 3 1 Glycosyl transferase family 4 DUF3341 PF11821.8 AAL64955.1 - 7.1 6.3 8.6 0.16 11.6 0.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3341) YndJ PF14158.6 AAL64956.1 - 0.02 14.2 2.6 0.023 14.0 2.6 1.1 1 0 0 1 1 1 0 YndJ-like protein Ras PF00071.22 AAL64957.1 - 4.7e-08 32.8 0.2 1.6e-07 31.0 0.2 1.8 1 1 0 1 1 1 1 Ras family Arf PF00025.21 AAL64957.1 - 2e-07 30.6 0.0 2.2e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 AAL64957.1 - 1.5e-06 28.3 0.0 2e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 AAL64957.1 - 0.00026 20.7 0.0 0.00062 19.5 0.0 1.6 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 AAL64957.1 - 0.0028 17.2 0.0 0.0059 16.1 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B Roc PF08477.13 AAL64957.1 - 0.011 16.0 0.1 0.043 14.0 0.1 1.8 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 AAL64957.1 - 0.012 15.0 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Hydrolase_3 PF08282.12 AAL64959.1 - 2.7e-28 99.4 0.0 1.1e-15 58.1 0.0 2.0 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.13 AAL64959.1 - 7.6e-10 38.7 0.2 1.1e-06 28.3 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 AAL64959.1 - 2.9e-06 27.7 2.1 0.15 12.3 0.0 3.2 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase HAD PF12710.7 AAL64959.1 - 2.1e-05 25.0 4.3 0.0011 19.4 0.1 3.2 1 1 2 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AAL64959.1 - 0.00089 19.3 0.1 0.0021 18.2 0.1 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.16 AAL64959.1 - 0.012 14.7 0.0 0.099 11.8 0.0 2.0 2 0 0 2 2 2 0 Trehalose-phosphatase Lactamase_B PF00753.27 AAL64961.1 - 0.0028 17.7 0.5 0.0065 16.5 0.5 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Herpes_U5 PF05999.11 AAL64961.1 - 0.21 10.3 0.0 6.6 5.4 0.0 2.0 2 0 0 2 2 2 0 Herpesvirus U5-like family DUF123 PF01986.16 AAL64962.1 - 2.2e-14 53.8 0.0 3e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF123 SIR2 PF02146.17 AAL64963.1 - 3e-56 190.1 0.0 3.6e-56 189.9 0.0 1.1 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 AAL64963.1 - 7.8e-05 22.4 0.0 0.0034 17.1 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain ADK_lid PF05191.14 AAL64963.1 - 0.031 14.3 1.4 0.058 13.4 1.4 1.5 1 0 0 1 1 1 0 Adenylate kinase, active site lid Zn_ribbon_SprT PF17283.2 AAL64963.1 - 5.4 7.0 5.7 79 3.3 5.7 2.3 1 1 0 1 1 1 0 SprT-like zinc ribbon domain HTH_45 PF14947.6 AAL64967.1 - 1.6e-11 44.0 0.0 2e-11 43.7 0.0 1.0 1 0 0 1 1 1 1 Winged helix-turn-helix DUF4364 PF14277.6 AAL64967.1 - 0.0097 15.7 0.0 0.012 15.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) Lon_C PF05362.13 AAL64969.1 - 6.3e-12 45.5 3.0 6.9e-12 45.3 1.5 1.7 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain ChlI PF13541.6 AAL64969.1 - 0.047 13.5 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Subunit ChlI of Mg-chelatase CstA PF02554.14 AAL64970.1 - 0.074 11.9 2.6 0.085 11.7 2.6 1.0 1 0 0 1 1 1 0 Carbon starvation protein CstA DUF805 PF05656.14 AAL64970.1 - 2.8 8.4 4.7 3.5 8.1 4.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF805) Resolvase PF00239.21 AAL64972.1 - 6.7e-34 117.1 0.3 9.3e-34 116.6 0.3 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain Sigma70_r4 PF04545.16 AAL64972.1 - 0.00083 18.8 2.4 0.012 15.1 0.0 2.6 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_Tnp_IS1 PF12759.7 AAL64972.1 - 0.0098 15.5 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 InsA C-terminal domain Complex1_LYR PF05347.15 AAL64972.1 - 0.014 15.4 0.3 0.043 13.9 0.3 1.9 1 0 0 1 1 1 0 Complex 1 protein (LYR family) HTH_23 PF13384.6 AAL64972.1 - 0.024 14.4 0.0 0.085 12.7 0.0 2.0 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 AAL64972.1 - 0.045 13.9 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 AAL64972.1 - 0.049 13.3 2.1 0.078 12.7 0.1 2.4 3 0 0 3 3 3 0 Sigma-70, region 4 GCP_N_terminal PF17681.1 AAL64972.1 - 0.089 12.4 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Gamma tubulin complex component N-terminal TnsD PF15978.5 AAL64972.1 - 0.095 11.7 1.8 0.15 11.0 0.1 1.8 1 1 1 2 2 2 0 Tn7-like transposition protein D Lar_restr_allev PF14354.6 AAL64972.1 - 0.096 13.1 0.9 0.22 11.9 0.9 1.5 1 0 0 1 1 1 0 Restriction alleviation protein Lar TniQ PF06527.11 AAL64972.1 - 0.13 13.0 0.1 0.21 12.3 0.1 1.5 1 0 0 1 1 1 0 TniQ Zn_Tnp_IS1595 PF12760.7 AAL64972.1 - 0.13 12.2 1.4 0.34 10.9 1.4 1.7 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Phage_antitermQ PF06530.12 AAL64972.1 - 0.13 12.1 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 Phage antitermination protein Q Pribosyltran PF00156.27 AAL64973.1 - 3.5e-20 72.1 0.0 5.5e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 AAL64973.1 - 0.00083 18.9 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase CTP_synth_N PF06418.14 AAL64976.1 - 2e-116 387.9 0.1 2.5e-116 387.6 0.1 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 AAL64976.1 - 7.4e-52 175.9 0.0 1.4e-51 175.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AAL64976.1 - 3e-08 33.7 0.0 1e-07 32.0 0.0 1.8 2 0 0 2 2 2 1 Peptidase C26 CbiA PF01656.23 AAL64976.1 - 5.1e-05 23.3 0.0 7.3e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 AAL64976.1 - 0.71 8.8 3.8 0.29 10.1 0.8 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Oxidored_q4 PF00507.19 AAL64977.1 - 1.1e-06 28.8 0.2 1.9e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 EamA PF00892.20 AAL64978.1 - 4.7e-10 39.8 34.2 1.3e-06 28.7 13.8 2.7 1 1 2 3 3 3 2 EamA-like transporter family SurE PF01975.17 AAL64979.1 - 1.2e-38 132.8 0.1 1.6e-38 132.5 0.1 1.1 1 0 0 1 1 1 1 Survival protein SurE L27_1 PF09058.10 AAL64980.1 - 0.031 14.2 0.3 0.064 13.2 0.1 1.7 2 0 0 2 2 2 0 L27_1 Spore_III_AB PF09548.10 AAL64980.1 - 0.086 12.9 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Helicase_C_2 PF13307.6 AAL64981.1 - 3.7e-11 43.5 0.0 6.1e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 AAL64981.1 - 2.6e-08 33.7 0.0 4.3e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 DEAD_2 DEAD PF00270.29 AAL64981.1 - 0.1 12.3 0.0 1.1 9.0 0.0 2.3 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_22 PF13401.6 AAL64981.1 - 0.18 12.1 0.0 12 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 AAL64982.1 - 7.4e-10 39.3 0.7 1.5e-09 38.3 0.7 1.5 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_22 PF13401.6 AAL64982.1 - 9.8e-07 29.1 0.1 0.024 14.9 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.6 AAL64982.1 - 1.8e-05 24.8 2.2 0.087 12.9 0.2 2.4 2 1 0 2 2 2 2 AAA domain ATPase PF06745.13 AAL64982.1 - 0.0046 16.3 0.0 0.039 13.3 0.0 2.1 2 1 0 2 2 2 1 KaiC IPT PF01745.16 AAL64982.1 - 0.016 14.6 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase CobU PF02283.16 AAL64982.1 - 0.017 14.7 0.0 0.089 12.4 0.0 2.1 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase DUF853 PF05872.12 AAL64982.1 - 0.018 13.7 0.0 1.1 7.7 0.0 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) ATPase_2 PF01637.18 AAL64982.1 - 0.023 14.6 7.1 0.47 10.3 7.1 2.4 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 AAL64982.1 - 0.042 14.4 0.0 0.092 13.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 AAL64982.1 - 0.15 11.0 0.2 1.3 7.9 0.0 2.1 2 1 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain OrfB_Zn_ribbon PF07282.11 AAL64983.1 - 3.2e-08 33.4 0.1 6.1e-08 32.5 0.1 1.5 1 0 0 1 1 1 1 Putative transposase DNA-binding domain PriA_CRR PF18319.1 AAL64983.1 - 0.0048 16.9 0.3 0.025 14.6 0.3 2.1 1 1 0 1 1 1 1 PriA DNA helicase Cys-rich region (CRR) domain Zn_Tnp_IS1595 PF12760.7 AAL64983.1 - 0.043 13.8 0.6 0.043 13.8 0.6 2.0 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Ribosomal_L37e PF01907.19 AAL64983.1 - 0.054 13.7 0.3 0.11 12.7 0.3 1.4 1 0 0 1 1 1 0 Ribosomal protein L37e zf-NADH-PPase PF09297.11 AAL64983.1 - 0.055 13.1 1.5 0.12 12.0 1.5 1.6 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain Cortex-I_coil PF09304.10 AAL64983.1 - 0.094 12.9 0.5 0.21 11.8 0.5 1.5 1 0 0 1 1 1 0 Cortexillin I, coiled coil DNA_RNApol_7kD PF03604.13 AAL64983.1 - 0.45 10.2 2.7 1.1 9.0 2.7 1.6 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Rubredoxin_2 PF18073.1 AAL64983.1 - 0.58 9.9 5.0 0.43 10.4 0.5 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain TrwB_AAD_bind PF10412.9 AAL64984.1 - 1.4e-06 27.5 0.0 0.0019 17.2 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 AAL64984.1 - 6.5e-05 23.1 0.0 0.00012 22.3 0.0 1.4 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_22 PF13401.6 AAL64984.1 - 0.001 19.3 0.0 0.089 13.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.7 AAL64984.1 - 0.0044 16.0 0.0 0.0065 15.4 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain AAA_30 PF13604.6 AAL64984.1 - 0.0061 16.3 0.0 0.044 13.5 0.1 2.1 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 AAL64984.1 - 0.013 15.7 0.0 0.027 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF853 PF05872.12 AAL64984.1 - 0.017 13.7 0.0 0.64 8.5 0.0 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) FtsK_SpoIIIE PF01580.18 AAL64984.1 - 0.059 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family CbiA PF01656.23 AAL64984.1 - 0.1 12.6 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain GIY-YIG PF01541.24 AAL64990.1 - 0.00027 21.1 0.0 0.00036 20.7 0.0 1.2 1 0 0 1 1 1 1 GIY-YIG catalytic domain SesA PF17107.5 AAL64991.1 - 0.022 14.9 0.9 0.074 13.2 0.2 2.1 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_16 PF13191.6 AAL64991.1 - 0.099 13.0 0.9 0.2 12.0 0.5 1.7 1 1 1 2 2 2 0 AAA ATPase domain PaRep2b PF07775.11 AAL64992.1 - 2.6e-143 478.2 9.3 1.5e-96 324.0 1.9 2.2 1 1 1 2 2 2 2 PaRep2b protein YtxH PF12732.7 AAL64992.1 - 0.065 13.8 2.6 0.26 11.9 0.9 2.6 2 0 0 2 2 2 0 YtxH-like protein Flu_NS2 PF00601.19 AAL64992.1 - 0.33 11.3 1.6 14 6.0 0.0 2.9 3 0 0 3 3 3 0 Influenza non-structural protein (NS2) Herpes_UL36 PF03586.13 AAL64992.1 - 1.3 8.2 4.9 1.9 7.7 0.0 3.0 4 0 0 4 4 4 0 Herpesvirus UL36 tegument protein DUF3253 PF11625.8 AAL64993.1 - 0.033 14.4 0.0 0.052 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3253) Peptidase_M48 PF01435.18 AAL64994.1 - 1.7e-17 63.9 0.3 2.7e-17 63.2 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 AAL64994.1 - 0.0058 15.9 6.9 0.01 15.0 0.3 2.8 2 1 1 3 3 3 2 BlaR1 peptidase M56 DUF2201_N PF13203.6 AAL64994.1 - 0.07 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain BtpA PF03437.15 AAL64997.1 - 1.5e-48 165.5 0.1 2.3e-48 164.8 0.1 1.3 1 1 0 1 1 1 1 BtpA family NMO PF03060.15 AAL64997.1 - 0.087 12.2 0.1 0.57 9.5 0.0 2.1 2 0 0 2 2 2 0 Nitronate monooxygenase GGA_N-GAT PF18308.1 AAL64997.1 - 0.11 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 GGA N-GAT domain NTP_transferase PF00483.23 AAL64998.1 - 4.6e-37 127.9 0.0 5.8e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 AAL64998.1 - 9.8e-14 50.4 23.9 6.1e-08 32.1 2.4 4.4 1 1 4 5 5 5 5 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 AAL64998.1 - 4.3e-09 36.9 0.0 6.8e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 AAL64998.1 - 0.00035 20.3 1.3 0.00035 20.3 1.3 3.9 2 1 1 3 3 3 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 AAL64998.1 - 0.0098 14.1 0.1 0.014 13.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) DprA_WH PF17782.1 AAL65000.1 - 0.024 14.7 0.1 0.036 14.2 0.1 1.3 1 0 0 1 1 1 0 DprA winged helix domain HIT PF01230.23 AAL65001.1 - 2.3e-13 50.7 0.0 3.2e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 HIT domain CwfJ_C_1 PF04677.15 AAL65001.1 - 1.9e-05 24.5 0.0 2.9e-05 23.9 0.0 1.3 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 DcpS_C PF11969.8 AAL65001.1 - 3.7e-05 24.2 0.0 7.5e-05 23.2 0.0 1.5 1 1 1 2 2 2 2 Scavenger mRNA decapping enzyme C-term binding PT-VENN PF04829.13 AAL65001.1 - 0.057 13.5 0.0 0.099 12.7 0.0 1.4 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif DUF3525 PF12039.8 AAL65001.1 - 0.18 10.5 0.0 0.22 10.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3525) AAA_15 PF13175.6 AAL65002.1 - 9.6e-05 22.3 0.0 0.00012 21.9 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 AAL65002.1 - 0.00048 19.8 0.0 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 AAL65002.1 - 0.00055 19.8 0.0 0.032 14.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AAL65002.1 - 0.0051 17.3 0.0 0.0071 16.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 AAL65002.1 - 0.0063 16.9 0.0 0.17 12.3 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 AAL65002.1 - 0.0095 15.7 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AAL65002.1 - 0.019 15.4 0.0 0.64 10.4 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain T2SSE PF00437.20 AAL65002.1 - 0.027 13.5 0.0 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_11 PF13086.6 AAL65002.1 - 0.046 13.5 0.0 0.066 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 AAL65002.1 - 0.072 12.5 0.0 0.17 11.3 0.0 1.6 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AAL65002.1 - 0.074 13.3 0.0 0.26 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain PIN_9 PF18477.1 AAL65003.1 - 1.5e-14 54.3 0.0 1.8e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 PIN like domain PIN_4 PF13638.6 AAL65003.1 - 3e-08 34.0 0.0 3.5e-06 27.3 0.0 2.1 1 1 1 2 2 2 2 PIN domain PIN PF01850.21 AAL65003.1 - 9.4e-06 26.1 1.2 0.00071 20.1 1.3 2.0 1 1 0 1 1 1 1 PIN domain DUF5615 PF18480.1 AAL65003.1 - 0.011 15.4 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) Mut7-C PF01927.16 AAL65003.1 - 0.015 15.4 0.0 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 Mut7-C RNAse domain DUF188 PF02639.14 AAL65003.1 - 0.04 13.6 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized BCR, YaiI/YqxD family COG1671 EutA PF06277.11 AAL65003.1 - 0.086 11.7 0.0 0.086 11.7 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutA PIN_3 PF13470.6 AAL65003.1 - 0.11 13.2 0.3 0.55 11.0 0.3 2.0 1 1 0 1 1 1 0 PIN domain SHS2_Rpb7-N PF03876.17 AAL65004.1 - 3.5e-19 68.9 0.0 6e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 AAL65004.1 - 2.5e-08 34.2 1.6 2.6e-08 34.1 0.2 1.7 2 0 0 2 2 2 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 AAL65004.1 - 0.0047 17.1 0.1 0.045 14.0 0.0 2.1 1 1 1 2 2 2 1 RNA polymerase III subunit Rpc25 Spt4 PF06093.13 AAL65005.1 - 3.3e-17 62.3 0.3 4e-17 62.1 0.3 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger DZR PF12773.7 AAL65005.1 - 0.00015 21.7 0.6 0.0002 21.3 0.6 1.2 1 0 0 1 1 1 1 Double zinc ribbon UPF0547 PF10571.9 AAL65005.1 - 0.00017 21.6 4.1 0.00027 21.0 4.1 1.3 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 zinc_ribbon_2 PF13240.6 AAL65005.1 - 0.00034 20.2 3.6 0.00052 19.6 3.6 1.3 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_15 PF17032.5 AAL65005.1 - 0.0011 19.7 2.0 0.0015 19.2 2.0 1.3 1 0 0 1 1 1 1 zinc-ribbon family TF_Zn_Ribbon PF08271.12 AAL65005.1 - 0.0016 17.9 0.6 0.024 14.1 0.0 2.2 2 0 0 2 2 2 1 TFIIB zinc-binding HypA PF01155.19 AAL65005.1 - 0.004 17.2 0.4 0.0049 16.9 0.4 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ribbon_3 PF13248.6 AAL65005.1 - 0.0071 15.7 3.7 0.011 15.1 3.7 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zf-RING_4 PF14570.6 AAL65005.1 - 0.014 15.2 2.0 0.022 14.5 2.0 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF35_N PF12172.8 AAL65005.1 - 0.02 14.8 0.6 0.031 14.2 0.6 1.3 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF2072 PF09845.9 AAL65005.1 - 0.041 14.2 2.6 0.054 13.8 2.2 1.4 1 1 0 1 1 1 0 Zn-ribbon containing protein zf-NADH-PPase PF09297.11 AAL65005.1 - 0.057 13.1 1.2 0.065 12.9 0.1 1.6 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 AAL65005.1 - 0.08 12.9 2.9 0.34 10.9 0.1 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf_UBZ PF18439.1 AAL65005.1 - 0.081 12.5 3.9 0.23 11.1 1.4 2.3 1 1 1 2 2 2 0 Ubiquitin-Binding Zinc Finger NRDD PF13597.6 AAL65005.1 - 0.16 10.7 0.8 0.19 10.5 0.8 1.0 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase zf-tcix PF14952.6 AAL65005.1 - 0.37 10.5 8.0 2.3 7.9 0.8 2.2 1 1 1 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding zf-RRN7 PF11781.8 AAL65005.1 - 0.5 10.1 3.5 0.67 9.7 0.3 2.1 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 tRNA-synt_2c PF01411.19 AAL65007.1 - 7.2e-121 404.4 0.0 2.6e-120 402.5 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 AAL65007.1 - 1.5e-14 53.8 0.1 3.9e-14 52.5 0.1 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2e PF02091.15 AAL65007.1 - 0.0034 16.7 0.1 0.0063 15.8 0.1 1.3 1 0 0 1 1 1 1 Glycyl-tRNA synthetase alpha subunit DrsE_2 PF13686.6 AAL65007.1 - 0.18 11.7 0.0 0.42 10.5 0.0 1.6 1 0 0 1 1 1 0 DsrE/DsrF/DrsH-like family NAC PF01849.18 AAL65008.1 - 0.0001 22.2 0.1 0.00019 21.3 0.1 1.5 1 0 0 1 1 1 1 NAC domain UBA PF00627.31 AAL65008.1 - 0.0056 16.6 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain PixA PF12306.8 AAL65008.1 - 0.049 13.8 0.0 0.052 13.7 0.0 1.1 1 0 0 1 1 1 0 Inclusion body protein HOIP-UBA PF16678.5 AAL65008.1 - 0.051 13.6 0.9 0.062 13.3 0.9 1.5 1 1 0 1 1 1 0 HOIP UBA domain pair DUF3562 PF12085.8 AAL65008.1 - 0.054 13.1 0.7 0.1 12.2 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3562) Ribosomal_L16 PF00252.18 AAL65009.1 - 7.4e-36 123.1 0.1 8.5e-36 122.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DUF2192 PF09958.9 AAL65010.1 - 4.2e-74 248.9 0.8 4.8e-74 248.8 0.8 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2192) SBP_bac_11 PF13531.6 AAL65011.1 - 0.029 14.1 0.1 0.068 12.9 0.1 1.9 1 1 0 1 1 1 0 Bacterial extracellular solute-binding protein ABC_tran PF00005.27 AAL65013.1 - 1.9e-18 67.3 0.0 2.7e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAL65013.1 - 7.7e-11 42.3 0.1 2.2e-05 24.4 0.1 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAL65013.1 - 8.3e-08 31.9 0.0 0.0017 17.8 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAL65013.1 - 1.9e-06 27.5 0.0 3.4e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AAL65013.1 - 0.0003 21.3 0.0 0.00044 20.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AAL65013.1 - 0.00042 20.6 0.0 0.00058 20.2 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 AAL65013.1 - 0.0021 17.8 0.0 0.003 17.3 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 AAL65013.1 - 0.0023 17.7 0.0 0.0035 17.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 AAL65013.1 - 0.0087 16.0 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 AAL65013.1 - 0.026 14.9 0.1 0.03 14.7 0.1 1.3 1 1 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 AAL65013.1 - 0.027 13.6 0.0 0.043 13.0 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.6 AAL65013.1 - 0.042 14.0 0.0 0.25 11.5 0.1 1.9 2 0 0 2 2 2 0 AAA domain DUF3584 PF12128.8 AAL65013.1 - 0.047 11.2 0.0 0.058 10.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_25 PF13481.6 AAL65013.1 - 0.049 13.2 0.0 0.091 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 AAL65013.1 - 0.053 13.0 0.0 0.082 12.4 0.0 1.4 1 1 0 1 1 1 0 PhoH-like protein SRP54 PF00448.22 AAL65013.1 - 0.054 13.1 0.0 0.089 12.4 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain MobB PF03205.14 AAL65013.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.14 AAL65013.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 AAL65013.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA PF00004.29 AAL65013.1 - 0.18 12.3 0.1 0.25 11.7 0.1 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 AAL65013.1 - 0.18 11.9 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 AAL65013.1 - 0.18 11.7 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase TsaE PF02367.17 AAL65013.1 - 0.2 11.7 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 AAL65013.1 - 0.21 11.1 0.1 0.32 10.6 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Abhydrolase_1 PF00561.20 AAL65014.1 - 1e-08 35.2 0.0 5.7e-06 26.2 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Esterase PF00756.20 AAL65014.1 - 1.7e-08 34.4 0.0 2.1e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 AAL65014.1 - 2.8e-08 33.3 0.0 1.6e-05 24.3 0.1 3.2 2 1 1 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AAL65014.1 - 1.2e-07 32.6 0.6 3.4e-05 24.5 0.6 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 AAL65014.1 - 2.2e-06 27.3 0.0 3.5e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family PGAP1 PF07819.13 AAL65014.1 - 0.0002 21.2 0.0 0.00024 20.9 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Peptidase_S15 PF02129.18 AAL65014.1 - 0.0033 17.1 0.0 0.0094 15.6 0.0 1.7 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.16 AAL65014.1 - 0.004 17.0 0.0 2.6 7.8 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase DLH PF01738.18 AAL65014.1 - 0.0043 16.6 0.1 0.081 12.5 0.0 2.5 2 1 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 AAL65014.1 - 0.0068 16.2 0.0 0.027 14.2 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family BAAT_C PF08840.11 AAL65014.1 - 0.017 15.1 0.0 0.024 14.6 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Lipase_3 PF01764.25 AAL65014.1 - 0.039 13.8 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Pribosyltran PF00156.27 AAL65014.1 - 0.056 13.0 0.0 0.8 9.2 0.0 2.1 2 0 0 2 2 2 0 Phosphoribosyl transferase domain FSH1 PF03959.13 AAL65014.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.5 1 1 0 1 1 1 0 Serine hydrolase (FSH1) PAC2 PF09754.9 AAL65015.1 - 1.2e-35 123.4 0.3 1.7e-35 123.0 0.3 1.2 1 0 0 1 1 1 1 PAC2 family DUF1561 PF07598.11 AAL65015.1 - 0.27 9.4 0.0 0.38 8.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1561) Ribosomal_L5_C PF00673.21 AAL65016.1 - 4.8e-24 84.4 0.0 9.8e-24 83.4 0.0 1.6 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 AAL65016.1 - 2.3e-18 66.3 0.1 4.2e-18 65.4 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 Late_protein_L1 PF00500.18 AAL65016.1 - 0.035 12.9 0.0 0.048 12.5 0.0 1.1 1 0 0 1 1 1 0 L1 (late) protein Metallophos_2 PF12850.7 AAL65017.1 - 5.4e-31 108.0 0.0 6.1e-31 107.8 0.0 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 AAL65017.1 - 3.3e-08 34.3 0.2 2.3e-05 25.0 0.0 2.1 1 1 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_3 PF14582.6 AAL65017.1 - 3e-06 26.7 0.0 0.00029 20.3 0.0 2.2 2 0 0 2 2 2 2 Metallophosphoesterase, calcineurin superfamily ETF PF01012.21 AAL65017.1 - 0.11 12.3 0.1 8.7 6.2 0.0 2.3 1 1 1 2 2 2 0 Electron transfer flavoprotein domain Methyltr_RsmB-F PF01189.17 AAL65018.1 - 2.7e-37 128.4 0.0 4e-37 127.8 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 AAL65018.1 - 1e-07 31.9 0.0 1.8e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAL65018.1 - 0.00023 21.8 0.0 0.00099 19.8 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain FtsJ PF01728.19 AAL65018.1 - 0.0012 19.0 0.0 0.0022 18.1 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 AAL65018.1 - 0.043 13.1 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.19 AAL65018.1 - 0.053 13.3 0.0 0.095 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 AAL65018.1 - 0.15 12.7 0.3 0.88 10.3 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain UPF0020 PF01170.18 AAL65018.1 - 0.17 11.5 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 DUF711 PF05167.12 AAL65020.1 - 2.1e-137 458.4 0.3 2.5e-137 458.1 0.3 1.0 1 0 0 1 1 1 1 Uncharacterised ACR (DUF711) ACT_6 PF13740.6 AAL65021.1 - 2.7e-17 62.5 1.0 3e-17 62.3 1.0 1.0 1 0 0 1 1 1 1 ACT domain ACT PF01842.25 AAL65021.1 - 7.9e-12 44.7 2.0 9.7e-12 44.5 2.0 1.1 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 AAL65021.1 - 2.5e-06 28.0 2.6 3.3e-06 27.6 2.6 1.2 1 0 0 1 1 1 1 ACT domain ACT_7 PF13840.6 AAL65021.1 - 7.4e-06 25.7 1.9 1.1e-05 25.1 1.9 1.3 1 0 0 1 1 1 1 ACT domain COMMD1_N PF17221.3 AAL65021.1 - 0.086 13.1 0.0 0.1 12.9 0.0 1.2 1 0 0 1 1 1 0 COMMD1 N-terminal domain UDPG_MGDP_dh_N PF03721.14 AAL65021.1 - 0.14 11.7 4.0 0.15 11.6 1.9 1.7 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Citrate_synt PF00285.21 AAL65022.1 - 1.6e-102 343.2 0.0 1.9e-102 343.0 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Citrate_synt PF00285.21 AAL65023.1 - 8e-09 35.0 0.1 8.4e-09 35.0 0.1 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain ETF PF01012.21 AAL65024.1 - 4.3e-49 166.9 7.5 5.2e-49 166.6 7.5 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Mastoparan PF08249.11 AAL65024.1 - 1.2 10.1 5.2 7.5 7.6 5.2 2.5 1 0 0 1 1 1 0 Mastoparan protein ETF_alpha PF00766.19 AAL65025.1 - 1.8e-31 108.0 0.0 3.4e-31 107.1 0.0 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.21 AAL65025.1 - 1.1e-21 77.5 5.0 1.9e-21 76.8 5.0 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain CBS PF00571.28 AAL65026.1 - 9.6e-22 77.2 2.8 2.6e-14 53.4 0.3 2.1 2 0 0 2 2 2 2 CBS domain BPL_LplA_LipB_2 PF16917.5 AAL65026.1 - 0.066 12.7 0.9 0.13 11.8 0.6 1.6 1 1 1 2 2 2 0 Biotin/lipoate A/B protein ligase family AMP-binding PF00501.28 AAL65027.1 - 2.7e-34 118.5 0.0 3.1e-34 118.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Proteasome PF00227.26 AAL65028.1 - 5.3e-55 185.9 0.2 5.9e-55 185.7 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit RTC PF01137.21 AAL65029.1 - 2.9e-85 285.0 0.1 3.5e-85 284.7 0.1 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 AAL65029.1 - 1.8e-25 89.4 0.2 3.3e-25 88.6 0.2 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain CelD_N PF02927.14 AAL65029.1 - 0.093 13.6 0.0 0.23 12.4 0.0 1.7 1 0 0 1 1 1 0 Cellulase N-terminal ig-like domain UbiA PF01040.18 AAL65030.1 - 2.5e-46 158.0 27.5 3.3e-46 157.6 27.5 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Cytochrom_C PF00034.21 AAL65031.1 - 2.1e-05 25.6 0.2 3.9e-05 24.7 0.2 1.7 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 AAL65031.1 - 0.0058 16.9 0.4 0.0094 16.3 0.4 1.7 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III DUF285 PF03382.14 AAL65031.1 - 0.18 11.6 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Mycoplasma protein of unknown function, DUF285 Cytochrom_D1 PF02239.16 AAL65032.1 - 1.9e-30 105.7 0.0 2.5e-21 75.6 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain DUF4221 PF13970.6 AAL65032.1 - 0.00065 19.4 0.0 0.62 9.6 0.0 3.2 3 1 0 4 4 4 2 Domain of unknown function (DUF4221) Lactonase PF10282.9 AAL65032.1 - 0.0013 18.0 0.0 0.65 9.2 0.0 3.1 3 0 0 3 3 3 2 Lactonase, 7-bladed beta-propeller TAT_signal PF10518.9 AAL65032.1 - 0.003 17.3 1.8 0.0049 16.7 1.8 1.4 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence PepSY PF03413.19 AAL65032.1 - 0.096 13.3 0.1 0.39 11.3 0.0 2.1 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain VID27 PF08553.10 AAL65032.1 - 0.13 11.3 0.0 0.28 10.2 0.0 1.4 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain TP_methylase PF00590.20 AAL65033.1 - 1.7e-35 122.9 0.6 2.9e-35 122.2 0.6 1.3 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Rhomboid_SP PF12595.8 AAL65033.1 - 0.09 12.1 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Rhomboid serine protease NnrS PF05940.12 AAL65034.1 - 8.7e-05 22.1 50.6 0.00012 21.6 50.6 1.1 1 0 0 1 1 1 1 NnrS protein COX1 PF00115.20 AAL65035.1 - 7.4e-33 114.0 59.2 7.4e-33 114.0 59.2 2.7 3 0 0 3 3 3 2 Cytochrome C and Quinol oxidase polypeptide I GerE PF00196.19 AAL65036.1 - 0.0012 18.3 0.2 0.0021 17.6 0.2 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_10 PF04967.12 AAL65036.1 - 0.04 13.7 0.2 1.2 9.0 0.2 2.3 1 1 0 1 1 1 0 HTH DNA binding domain HTH_7 PF02796.15 AAL65036.1 - 0.052 13.6 0.1 0.13 12.4 0.1 1.8 1 1 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 AAL65036.1 - 0.056 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain UPF0122 PF04297.14 AAL65036.1 - 0.072 13.3 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like HTH_10 PF04967.12 AAL65037.1 - 6.8e-05 22.6 0.4 0.0014 18.3 0.0 2.5 3 0 0 3 3 3 1 HTH DNA binding domain Sigma70_r4 PF04545.16 AAL65037.1 - 0.00015 21.2 1.1 0.00023 20.6 0.0 1.9 2 1 0 2 2 2 1 Sigma-70, region 4 MarR_2 PF12802.7 AAL65037.1 - 0.027 14.4 0.4 0.073 13.0 0.0 1.9 2 1 0 2 2 2 0 MarR family Sigma70_r4_2 PF08281.12 AAL65037.1 - 0.041 13.6 0.1 0.041 13.6 0.1 2.3 2 1 0 2 2 2 0 Sigma-70, region 4 P22_Cro PF14549.6 AAL65037.1 - 0.06 13.2 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro DUF2715 PF10895.8 AAL65039.1 - 0.01 15.5 0.2 0.018 14.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2715) HTH_IclR PF09339.10 AAL65040.1 - 0.00012 21.8 0.5 0.00046 19.9 0.1 2.0 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_5 PF01022.20 AAL65040.1 - 0.0029 17.4 1.1 0.2 11.6 0.2 2.3 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 AAL65040.1 - 0.0036 16.8 0.0 0.01 15.4 0.1 1.7 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 AAL65040.1 - 0.0044 16.9 0.1 0.033 14.1 0.1 2.0 2 0 0 2 2 2 1 MarR family TrmB PF01978.19 AAL65040.1 - 0.0045 16.8 0.0 0.019 14.8 0.0 1.9 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.7 AAL65040.1 - 0.017 15.2 0.3 0.53 10.4 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 AAL65040.1 - 0.11 12.4 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Nitrate_red_del PF02613.15 AAL65041.1 - 7.8e-13 48.6 0.1 1.1e-12 48.1 0.1 1.2 1 0 0 1 1 1 1 Nitrate reductase delta subunit Molybdopterin PF00384.22 AAL65042.1 - 2e-131 438.9 0.0 2.3e-71 241.0 0.0 2.1 2 0 0 2 2 2 2 Molybdopterin oxidoreductase Molydop_binding PF01568.21 AAL65042.1 - 2.5e-21 75.8 0.1 7.6e-21 74.2 0.1 1.8 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Nitr_red_alph_N PF14710.6 AAL65042.1 - 0.0017 18.8 1.0 0.0047 17.3 1.0 1.8 1 0 0 1 1 1 1 Respiratory nitrate reductase alpha N-terminal Molybdop_Fe4S4 PF04879.16 AAL65042.1 - 0.003 17.5 0.0 0.01 15.8 0.0 1.9 2 0 0 2 2 2 1 Molybdopterin oxidoreductase Fe4S4 domain DUF4738 PF15889.5 AAL65042.1 - 0.094 12.6 0.0 0.31 10.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4738) Fer4_11 PF13247.6 AAL65043.1 - 3.6e-35 120.1 8.1 3.6e-35 120.1 8.1 1.7 2 0 0 2 2 1 1 4Fe-4S dicluster domain Nitr_red_bet_C PF14711.6 AAL65043.1 - 1.1e-26 92.3 0.0 2e-26 91.5 0.0 1.4 1 0 0 1 1 1 1 Respiratory nitrate reductase beta C-terminal Fer4_7 PF12838.7 AAL65043.1 - 7.5e-07 29.7 18.7 0.00015 22.2 6.0 3.3 2 1 1 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAL65043.1 - 2.5e-06 27.5 19.7 5e-05 23.3 6.7 3.2 2 1 1 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.7 AAL65043.1 - 5.9e-05 23.0 22.3 0.067 13.3 0.4 4.3 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4_2 PF12797.7 AAL65043.1 - 0.00036 20.5 25.8 0.033 14.3 2.4 4.4 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4 PF00037.27 AAL65043.1 - 0.0016 18.2 19.9 0.044 13.6 2.2 4.5 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_9 PF13187.6 AAL65043.1 - 0.0027 17.9 21.2 0.014 15.6 6.1 3.2 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_15 PF13459.6 AAL65043.1 - 0.017 15.9 9.4 0.93 10.3 0.4 3.5 3 1 0 3 3 3 0 4Fe-4S single cluster domain Fer4_13 PF13370.6 AAL65043.1 - 0.032 14.8 11.2 0.077 13.5 0.2 3.5 3 0 0 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_17 PF13534.6 AAL65043.1 - 0.041 14.4 18.3 0.86 10.2 1.4 3.7 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 AAL65043.1 - 0.048 13.8 21.0 0.14 12.3 1.9 2.9 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 AAL65043.1 - 0.2 12.1 0.1 0.2 12.1 0.1 3.5 2 1 1 3 3 2 0 4Fe-4S dicluster domain Fer4_19 PF06902.11 AAL65043.1 - 4.8 7.3 7.3 7.4 6.7 0.8 2.4 2 0 0 2 2 2 0 Divergent 4Fe-4S mono-cluster Fer4_16 PF13484.6 AAL65043.1 - 8.7 7.4 19.8 16 6.5 1.2 3.6 2 1 1 3 3 3 0 4Fe-4S double cluster binding domain EB_dh PF09459.10 AAL65044.1 - 2.4e-36 126.0 0.0 7e-36 124.5 0.0 1.7 1 1 0 1 1 1 1 Ethylbenzene dehydrogenase DUF3123 PF11321.8 AAL65044.1 - 0.017 15.8 1.4 0.036 14.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) DUF945 PF06097.11 AAL65045.1 - 0.23 10.5 1.0 0.31 10.1 1.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) ABC2_membrane_3 PF12698.7 AAL65048.1 - 0.021 13.9 5.3 0.019 14.1 4.3 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein ABC_tran PF00005.27 AAL65049.1 - 1e-21 77.9 0.0 1.4e-21 77.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAL65049.1 - 2.4e-08 34.2 0.6 0.0041 17.0 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AAL65049.1 - 0.00017 21.2 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.6 AAL65049.1 - 0.0052 15.5 0.0 0.0066 15.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain DUF3584 PF12128.8 AAL65049.1 - 0.0052 14.4 0.1 0.0066 14.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_23 PF13476.6 AAL65049.1 - 0.014 15.9 0.0 0.019 15.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 AAL65049.1 - 0.018 15.4 0.1 0.053 13.9 0.1 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AAL65049.1 - 0.025 15.0 0.2 0.031 14.7 0.2 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 AAL65049.1 - 0.045 13.9 0.0 0.12 12.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_8 PF12780.7 AAL65049.1 - 0.07 12.4 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 DLIC PF05783.11 AAL65049.1 - 0.075 11.9 0.1 0.13 11.0 0.1 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_22 PF13401.6 AAL65049.1 - 0.075 13.3 0.1 0.16 12.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 AAL65049.1 - 0.11 12.3 0.1 0.16 11.9 0.1 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 AAL65049.1 - 0.13 12.0 0.1 0.19 11.4 0.1 1.2 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 AAL65049.1 - 0.15 11.1 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 AAL65049.1 - 0.17 11.6 0.2 0.26 11.0 0.2 1.5 1 1 0 1 1 1 0 AAA domain Cytochrom_C_asm PF01578.20 AAL65050.1 - 1.4e-15 57.7 5.4 1.4e-15 57.7 5.4 2.2 2 0 0 2 2 2 1 Cytochrome C assembly protein MASE3 PF17159.4 AAL65050.1 - 0.097 12.3 16.6 0.058 13.0 3.9 2.5 3 0 0 3 3 3 0 Membrane-associated sensor domain OST3_OST6 PF04756.13 AAL65050.1 - 0.25 10.7 5.3 0.41 9.9 0.5 2.3 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family DUF4131 PF13567.6 AAL65050.1 - 4 7.1 25.0 0.062 12.9 3.2 3.5 5 0 0 5 5 5 0 Domain of unknown function (DUF4131) Flavi_NS4A PF01350.17 AAL65051.1 - 0.17 11.8 0.3 0.23 11.4 0.3 1.2 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4A Cytochrom_C_asm PF01578.20 AAL65052.1 - 5.1e-10 39.5 17.0 5.1e-10 39.5 17.0 3.4 3 2 1 4 4 4 2 Cytochrome C assembly protein TNFR_16_TM PF18422.1 AAL65053.1 - 0.3 11.1 0.2 0.3 11.1 0.2 2.4 3 0 0 3 3 3 0 Tumor necrosis factor receptor member 16 trans-membrane domain NOG1 PF06858.14 AAL65054.1 - 6.2e-23 80.3 0.0 4.5e-22 77.6 0.0 2.3 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) NOG1_N PF17835.1 AAL65054.1 - 5.4e-22 78.5 0.8 8.3e-22 77.9 0.8 1.3 1 0 0 1 1 1 1 NOG1 N-terminal helical domain MMR_HSR1 PF01926.23 AAL65054.1 - 6.9e-19 68.0 0.0 1.5e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AAL65054.1 - 1.3e-12 47.5 0.0 2.1e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.16 AAL65054.1 - 0.0012 18.2 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 AAL65054.1 - 0.0062 16.5 0.1 2.7 7.9 0.0 2.8 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1_Xtn PF16897.5 AAL65054.1 - 0.0074 16.3 0.0 0.25 11.4 0.0 2.5 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain cobW PF02492.19 AAL65054.1 - 0.035 13.7 0.0 0.075 12.6 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 AAL65054.1 - 0.087 12.9 0.3 3.5 7.7 0.0 2.4 1 1 1 2 2 2 0 Dynamin family ATP_bind_1 PF03029.17 AAL65054.1 - 0.13 12.0 0.0 4.8 6.9 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SAM_adeno_trans PF01887.16 AAL65055.1 - 4.4e-84 281.6 0.0 5e-84 281.4 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-l-methionine hydroxide adenosyltransferase SBBP PF06739.11 AAL65055.1 - 0.071 13.1 0.2 0.17 11.9 0.2 1.5 1 0 0 1 1 1 0 Beta-propeller repeat DUF2187 PF09953.9 AAL65055.1 - 0.13 12.3 0.0 2.6 8.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2187) PaRep2a PF07903.11 AAL65056.1 - 0.012 15.5 0.0 0.012 15.5 0.0 1.0 1 0 0 1 1 1 0 PaRep2a protein CarboxypepD_reg PF13620.6 AAL65057.1 - 8.2e-05 22.8 0.0 0.00028 21.1 0.0 1.9 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain Epimerase PF01370.21 AAL65058.1 - 1.9e-14 53.7 0.0 2.7e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 AAL65058.1 - 2.3e-09 36.7 0.0 8.9e-09 34.8 0.0 2.0 1 1 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 AAL65058.1 - 2.5e-06 27.2 0.0 3.1e-05 23.5 0.0 2.3 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 AAL65058.1 - 0.00076 18.6 0.2 0.017 14.2 0.2 2.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Cytochrom_C_2 PF01322.20 AAL65061.1 - 0.015 16.2 0.0 5.7 7.9 0.0 2.6 2 1 1 3 3 3 0 Cytochrome C' DUF3517 PF12030.8 AAL65061.1 - 0.056 12.4 0.0 0.074 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3517) RuvA_C PF07499.13 AAL65061.1 - 0.065 13.7 0.4 44 4.6 0.0 3.4 3 0 0 3 3 3 0 RuvA, C-terminal domain TetR_C_6 PF13977.6 AAL65061.1 - 0.18 12.0 3.0 0.24 11.6 0.8 2.2 2 1 0 2 2 2 0 BetI-type transcriptional repressor, C-terminal Zip PF02535.22 AAL65062.1 - 2e-20 73.3 16.5 1e-18 67.7 5.8 2.1 1 1 1 2 2 2 2 ZIP Zinc transporter E1-E2_ATPase PF00122.20 AAL65062.1 - 0.37 10.3 6.3 0.94 9.0 0.1 2.9 1 1 1 3 3 3 0 E1-E2 ATPase Band_7_1 PF13421.6 AAL65063.1 - 1.1e-30 106.9 0.0 1.7e-30 106.4 0.0 1.2 1 0 0 1 1 1 1 SPFH domain-Band 7 family Band_7 PF01145.25 AAL65063.1 - 6.2e-17 62.2 0.1 9.7e-17 61.5 0.1 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family zinc_ribbon_2 PF13240.6 AAL65063.1 - 4.4e-16 58.0 15.9 3.5e-08 32.9 4.8 2.3 2 0 0 2 2 2 2 zinc-ribbon domain DZR PF12773.7 AAL65063.1 - 6.9e-15 54.8 21.0 8.6e-12 44.9 11.4 1.8 1 1 1 2 2 2 2 Double zinc ribbon zf-ribbon_3 PF13248.6 AAL65063.1 - 2.1e-10 39.7 16.4 3.6e-06 26.2 5.3 2.3 2 0 0 2 2 2 2 zinc-ribbon domain zinc_ribbon_15 PF17032.5 AAL65063.1 - 2.4e-05 25.0 6.6 0.057 14.2 0.2 2.3 2 0 0 2 2 2 2 zinc-ribbon family zf-tcix PF14952.6 AAL65063.1 - 0.00012 21.7 12.4 0.0037 16.8 1.8 2.3 1 1 1 2 2 2 2 Putative treble-clef, zinc-finger, Zn-binding zf-RanBP PF00641.18 AAL65063.1 - 0.00021 20.6 7.5 0.091 12.1 1.6 2.2 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DUF35_N PF12172.8 AAL65063.1 - 0.00036 20.3 10.6 0.0012 18.7 0.7 2.4 2 0 0 2 2 2 1 Rubredoxin-like zinc ribbon domain (DUF35_N) HNH_repeat PF18780.1 AAL65063.1 - 0.0049 16.6 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Homing endonuclease repeat UPF0547 PF10571.9 AAL65063.1 - 0.014 15.5 20.3 0.045 13.8 5.6 3.1 2 1 0 2 2 2 0 Uncharacterised protein family UPF0547 DHHC PF01529.20 AAL65063.1 - 0.12 12.5 5.5 3.3 7.8 0.2 2.4 1 1 1 2 2 2 0 DHHC palmitoyltransferase zf-TRM13_CCCH PF11722.8 AAL65063.1 - 0.12 12.1 3.4 6.7 6.6 0.8 2.3 1 1 1 2 2 2 0 CCCH zinc finger in TRM13 protein OrfB_Zn_ribbon PF07282.11 AAL65063.1 - 0.35 10.8 8.6 1.4 8.9 1.3 2.5 1 1 1 2 2 2 0 Putative transposase DNA-binding domain TF_Zn_Ribbon PF08271.12 AAL65063.1 - 0.41 10.2 11.5 3.3 7.3 0.1 3.6 2 1 1 3 3 3 0 TFIIB zinc-binding Nudix_N_2 PF14803.6 AAL65063.1 - 0.98 9.4 17.6 9.1 6.3 0.3 4.2 3 1 1 4 4 4 0 Nudix N-terminal zf-FPG_IleRS PF06827.14 AAL65063.1 - 2.1 8.3 7.6 2.3 8.2 1.1 3.2 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS A2L_zn_ribbon PF08792.10 AAL65063.1 - 5.3 6.9 15.9 0.77 9.5 0.5 4.1 4 0 0 4 4 4 0 A2L zinc ribbon domain zf-NADH-PPase PF09297.11 AAL65063.1 - 7.7 6.3 13.0 6.7 6.5 0.3 3.7 4 0 0 4 4 3 0 NADH pyrophosphatase zinc ribbon domain PsbH PF00737.20 AAL65064.1 - 9.2 6.1 8.0 2 8.2 4.1 2.0 2 1 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein DUF1152 PF06626.12 AAL65065.1 - 4.9e-90 301.7 0.4 5.6e-90 301.5 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1152) TF_Zn_Ribbon PF08271.12 AAL65067.1 - 9.5e-09 34.6 0.4 1.6e-08 33.9 0.4 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding zf-ribbon_3 PF13248.6 AAL65067.1 - 0.00019 20.7 0.7 0.081 12.4 0.0 2.2 2 0 0 2 2 2 2 zinc-ribbon domain zinc_ribbon_4 PF13717.6 AAL65067.1 - 0.0046 16.9 1.1 0.035 14.0 1.1 2.1 1 1 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 AAL65067.1 - 0.013 15.5 0.2 0.022 14.8 0.2 1.2 1 0 0 1 1 1 0 Double zinc ribbon zf-RRN7 PF11781.8 AAL65067.1 - 0.024 14.3 0.4 0.024 14.3 0.4 1.9 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zinc_ribbon_2 PF13240.6 AAL65067.1 - 0.054 13.2 4.8 0.34 10.7 4.8 2.0 1 1 1 2 2 2 0 zinc-ribbon domain zf-BED PF02892.15 AAL65067.1 - 0.12 12.4 0.6 0.85 9.7 0.0 2.1 1 1 1 2 2 2 0 BED zinc finger zf-Di19 PF05605.12 AAL65067.1 - 0.14 12.5 2.5 11 6.5 0.1 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_5 PF13719.6 AAL65067.1 - 0.19 11.5 0.9 1 9.1 0.2 2.1 2 0 0 2 2 2 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 AAL65067.1 - 0.24 11.4 0.2 0.4 10.6 0.2 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-C2H2_4 PF13894.6 AAL65067.1 - 0.35 11.8 1.9 33 5.7 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Cys_rich_CPXG PF14255.6 AAL65067.1 - 0.41 10.6 6.1 4.6 7.2 0.4 2.7 3 0 0 3 3 3 0 Cysteine-rich CPXCG zf-H2C2_2 PF13465.6 AAL65067.1 - 0.54 10.8 2.2 19 5.9 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double domain UPF0547 PF10571.9 AAL65067.1 - 0.73 10.0 3.9 6.3 7.0 0.4 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 A2L_zn_ribbon PF08792.10 AAL65067.1 - 0.87 9.4 3.1 17 5.3 0.4 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-CHCC PF10276.9 AAL65067.1 - 1.1 9.4 4.5 9.2 6.4 1.1 2.4 2 0 0 2 2 2 0 Zinc-finger domain Prok-RING_1 PF14446.6 AAL65067.1 - 2.2 8.3 3.4 12 5.9 3.4 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zinc_ribbon_2 PF13240.6 AAL65068.1 - 0.0093 15.7 1.6 1.5 8.6 0.1 2.2 2 0 0 2 2 2 2 zinc-ribbon domain zf-ribbon_3 PF13248.6 AAL65068.1 - 0.0099 15.3 3.8 0.048 13.1 3.8 2.0 1 1 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 AAL65068.1 - 0.041 13.9 0.5 0.062 13.3 0.5 1.2 1 0 0 1 1 1 0 Double zinc ribbon Prok-RING_1 PF14446.6 AAL65068.1 - 0.047 13.6 1.6 0.073 13.0 1.6 1.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 A2L_zn_ribbon PF08792.10 AAL65068.1 - 0.25 11.1 1.3 0.65 9.8 1.2 1.7 1 1 0 1 1 1 0 A2L zinc ribbon domain TF_Zn_Ribbon PF08271.12 AAL65068.1 - 0.42 10.2 1.9 0.76 9.4 1.9 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding zf-CHCC PF10276.9 AAL65068.1 - 0.44 10.6 3.1 3.6 7.7 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger domain PyrI_C PF02748.15 AAL65068.1 - 2 8.4 3.6 13 5.8 0.1 2.3 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Aminotran_1_2 PF00155.21 AAL65069.1 - 1.8e-14 53.7 0.0 4.6e-14 52.4 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II ATP_bind_3 PF01171.20 AAL65070.1 - 1.3e-11 44.6 0.0 2.5e-11 43.7 0.0 1.4 1 1 0 1 1 1 1 PP-loop family tRNA_Me_trans PF03054.16 AAL65070.1 - 3.6e-05 22.7 0.7 9.6e-05 21.3 0.7 1.6 1 1 0 1 1 1 1 tRNA methyl transferase PAPS_reduct PF01507.19 AAL65070.1 - 0.00099 19.2 0.0 0.0014 18.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family QueC PF06508.13 AAL65070.1 - 0.0011 18.5 0.1 0.0044 16.5 0.0 1.9 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC RecR PF02132.15 AAL65070.1 - 0.007 15.9 4.5 0.013 15.1 1.3 2.4 2 0 0 2 2 2 1 RecR protein Asn_synthase PF00733.21 AAL65070.1 - 0.0093 15.7 0.0 0.012 15.3 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase C1_2 PF03107.16 AAL65070.1 - 0.092 13.1 0.5 0.75 10.2 0.1 2.4 2 0 0 2 2 2 0 C1 domain zf-HIT PF04438.16 AAL65070.1 - 0.13 12.2 6.7 1.4 8.8 0.2 2.8 2 1 0 2 2 2 0 HIT zinc finger NAD_synthase PF02540.17 AAL65070.1 - 0.19 10.8 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 NAD synthase zn-ribbon_14 PF16503.5 AAL65070.1 - 0.41 10.2 5.2 0.15 11.6 1.1 2.1 2 0 0 2 2 2 0 Zinc-ribbon zf-ribbon_3 PF13248.6 AAL65070.1 - 0.53 9.8 3.9 3.3 7.2 0.5 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-RRN7 PF11781.8 AAL65070.1 - 1.9 8.3 7.0 1.7 8.4 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 PTS_2-RNA PF01885.16 AAL65071.1 - 3.1e-29 102.3 0.0 3.8e-29 102.0 0.0 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family DUF1958 PF09211.10 AAL65071.1 - 0.0074 16.6 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1958) Desulfoferrod_N PF06397.12 AAL65071.1 - 0.013 15.1 1.3 0.029 14.0 1.3 1.7 1 1 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain PARP PF00644.20 AAL65071.1 - 0.026 14.1 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase catalytic domain HTH_24 PF13412.6 AAL65072.1 - 1.9e-07 30.5 0.0 3e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 AAL65072.1 - 3.7e-06 26.6 0.0 7.1e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_20 PF12840.7 AAL65072.1 - 2e-05 24.6 0.0 3.6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 AAL65072.1 - 0.00058 19.7 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family TrmB PF01978.19 AAL65072.1 - 0.00074 19.4 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 AAL65072.1 - 0.0018 18.1 0.1 0.0038 17.1 0.1 1.6 1 0 0 1 1 1 1 MarR family HTH_36 PF13730.6 AAL65072.1 - 0.0028 17.6 0.0 0.0059 16.5 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_34 PF13601.6 AAL65072.1 - 0.0087 16.2 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain AbiEi_4 PF13338.6 AAL65072.1 - 0.025 14.7 0.0 0.083 13.1 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin Fe_dep_repress PF01325.19 AAL65072.1 - 0.033 14.4 0.0 0.06 13.6 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain MarR PF01047.22 AAL65072.1 - 0.096 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 MarR family Herpes_gE PF02480.16 AAL65072.1 - 0.13 11.0 3.3 2.6 6.7 0.8 2.2 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E RP-C PF03428.13 AAL65072.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Replication protein C N-terminal domain DUF908 PF06012.12 AAL65072.1 - 0.39 10.1 0.7 0.54 9.6 0.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) PaREP1 PF05942.11 AAL65073.1 - 1.5e-20 73.2 2.3 2.6e-20 72.5 2.3 1.4 1 0 0 1 1 1 1 Archaeal PaREP1/PaREP8 family HEPN PF05168.14 AAL65073.1 - 1e-05 25.7 0.4 1e-05 25.7 0.4 1.5 2 0 0 2 2 2 1 HEPN domain DUF357 PF04010.13 AAL65073.1 - 0.11 12.5 0.1 0.27 11.4 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF357) Meth_synt_2 PF01717.18 AAL65074.1 - 4.6e-38 131.3 0.0 3.6e-23 82.3 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 AAL65074.1 - 0.00019 21.0 0.3 0.1 12.1 0.0 2.7 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain Thiolase_N PF00108.23 AAL65075.1 - 2.7e-64 217.0 0.0 3.8e-64 216.6 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 AAL65075.1 - 7.3e-47 158.0 0.9 2.2e-46 156.5 0.6 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 AAL65075.1 - 5.7e-06 26.1 0.6 0.0002 21.0 0.1 2.9 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Apocytochr_F_N PF16639.5 AAL65075.1 - 0.059 13.6 0.0 0.099 12.9 0.0 1.3 1 0 0 1 1 1 0 Apocytochrome F, N-terminal SBP_bac_8 PF13416.6 AAL65076.1 - 3e-10 40.4 0.3 1.2e-09 38.5 0.0 2.0 2 1 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AAL65076.1 - 4.8e-09 36.0 0.5 8.6e-09 35.2 0.0 1.6 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein PaREP1 PF05942.11 AAL65077.1 - 2.6e-09 37.0 2.2 8e-09 35.4 2.2 1.7 1 1 0 1 1 1 1 Archaeal PaREP1/PaREP8 family DUF5618 PF18498.1 AAL65077.1 - 0.0027 17.9 1.1 0.0035 17.5 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5618) HEPN PF05168.14 AAL65077.1 - 0.052 13.7 4.3 0.079 13.1 4.3 1.3 1 0 0 1 1 1 0 HEPN domain EDS1_EP PF18117.1 AAL65077.1 - 0.073 13.5 0.1 0.14 12.6 0.0 1.4 2 0 0 2 2 2 0 Enhanced disease susceptibility 1 protein EP domain HTH_45 PF14947.6 AAL65078.1 - 1.3e-20 73.1 0.0 1.6e-20 72.9 0.0 1.0 1 0 0 1 1 1 1 Winged helix-turn-helix AAA_assoc_C PF09821.9 AAL65078.1 - 0.00076 20.0 0.0 0.0012 19.3 0.0 1.3 1 0 0 1 1 1 1 C-terminal AAA-associated domain TrmB PF01978.19 AAL65078.1 - 0.005 16.7 0.0 0.0063 16.4 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_27 PF13463.6 AAL65078.1 - 0.017 15.6 0.0 0.024 15.1 0.0 1.4 1 1 0 1 1 1 0 Winged helix DNA-binding domain Topoisom_bac PF01131.20 AAL65078.1 - 0.026 13.5 0.0 0.034 13.2 0.0 1.1 1 0 0 1 1 1 0 DNA topoisomerase Transposase_22 PF02994.14 AAL65078.1 - 0.029 14.6 0.1 0.055 13.6 0.0 1.5 1 1 1 2 2 2 0 L1 transposable element RBD-like domain HemN_C PF06969.16 AAL65078.1 - 0.03 14.4 0.0 0.046 13.8 0.0 1.3 1 0 0 1 1 1 0 HemN C-terminal domain FtsK_gamma PF09397.10 AAL65078.1 - 0.084 12.7 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Ftsk gamma domain Rrf2 PF02082.20 AAL65078.1 - 0.13 12.7 0.0 0.17 12.2 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator MerC PF03203.14 AAL65079.1 - 8.1 6.9 11.6 1.1 9.7 2.2 2.3 1 1 1 2 2 2 0 MerC mercury resistance protein FtsX PF02687.21 AAL65080.1 - 9e-14 51.7 1.7 9e-14 51.7 1.7 3.6 3 1 0 3 3 3 1 FtsX-like permease family MacB_PCD PF12704.7 AAL65080.1 - 1.8e-09 38.2 11.5 1.8e-09 38.2 11.5 2.8 3 1 0 3 3 3 1 MacB-like periplasmic core domain DUF4064 PF13273.6 AAL65080.1 - 0.058 13.7 8.5 1.8 8.9 0.4 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) DUF2273 PF10031.9 AAL65080.1 - 0.082 12.9 0.6 0.082 12.9 0.6 3.7 4 0 0 4 4 4 0 Small integral membrane protein (DUF2273) NPCBM_assoc PF10633.9 AAL65081.1 - 0.00012 22.2 6.5 0.0021 18.3 0.0 4.1 4 1 0 4 4 4 1 NPCBM-associated, NEW3 domain of alpha-galactosidase CARDB PF07705.11 AAL65081.1 - 0.046 14.0 15.2 0.24 11.7 0.1 4.0 3 1 0 3 3 3 0 CARDB DUF3244 PF11589.8 AAL65081.1 - 0.6 10.2 5.5 0.62 10.2 0.2 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF3244) PKD PF00801.20 AAL65081.1 - 0.83 9.5 7.9 0.22 11.4 0.3 3.9 3 2 0 3 3 3 0 PKD domain DUF11 PF01345.18 AAL65081.1 - 0.99 9.7 19.3 0.1 12.9 2.3 4.3 2 2 0 3 3 3 0 Domain of unknown function DUF11 fn3_5 PF06280.12 AAL65081.1 - 9 7.0 8.8 2.3 8.9 1.3 3.3 3 0 0 3 3 3 0 Fn3-like domain PKI PF02827.16 AAL65082.1 - 0.11 12.7 0.0 0.62 10.3 0.0 1.9 2 0 0 2 2 2 0 cAMP-dependent protein kinase inhibitor LptF_LptG PF03739.14 AAL65083.1 - 0.061 12.2 10.4 0.078 11.8 10.4 1.1 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG DUF2062 PF09835.9 AAL65083.1 - 0.19 11.6 11.9 0.5 10.2 11.9 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) DUF2721 PF11026.8 AAL65083.1 - 2.6 8.0 12.3 0.18 11.7 6.3 1.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2721) FtsX PF02687.21 AAL65084.1 - 5.2 7.6 13.8 0.35 11.3 0.8 3.3 3 0 0 3 3 3 0 FtsX-like permease family Radical_SAM PF04055.21 AAL65085.1 - 6.9e-27 94.9 0.0 5.3e-26 92.0 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily zinc_ribbon_2 PF13240.6 AAL65085.1 - 0.0022 17.7 3.2 0.87 9.4 0.1 2.8 2 0 0 2 2 2 2 zinc-ribbon domain zf-NADH-PPase PF09297.11 AAL65085.1 - 0.013 15.1 2.9 0.07 12.8 0.1 2.6 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zf-C4_Topoisom PF01396.19 AAL65085.1 - 0.014 15.1 1.5 2.4 8.0 0.3 2.7 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger DZR PF12773.7 AAL65085.1 - 0.021 14.8 0.2 0.021 14.8 0.2 2.4 3 0 0 3 3 3 0 Double zinc ribbon DNA_ligase_ZBD PF03119.16 AAL65085.1 - 0.11 12.5 2.2 2.5 8.2 0.1 2.9 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain PknG_rubred PF16919.5 AAL65085.1 - 0.22 11.7 0.8 0.5 10.5 0.8 1.5 1 0 0 1 1 1 0 Protein kinase G rubredoxin domain zf-ribbon_3 PF13248.6 AAL65085.1 - 0.26 10.7 9.1 2 7.9 0.4 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zf_C2H2_10 PF18414.1 AAL65085.1 - 2.9 7.5 4.2 19 4.9 0.6 2.5 2 0 0 2 2 2 0 C2H2 type zinc-finger PaREP1 PF05942.11 AAL65086.1 - 7.6e-33 112.9 0.3 7.6e-33 112.9 0.3 1.5 2 0 0 2 2 2 1 Archaeal PaREP1/PaREP8 family Pro_CA PF00484.19 AAL65088.1 - 7.2e-23 81.6 0.1 9.2e-23 81.3 0.1 1.1 1 0 0 1 1 1 1 Carbonic anhydrase OST_IS PF18246.1 AAL65088.1 - 0.027 14.7 0.0 0.074 13.3 0.0 1.6 2 0 0 2 2 2 0 Oligosaccharyltransferase Insert domain Abhydrolase_1 PF00561.20 AAL65088.1 - 0.051 13.2 0.0 0.058 13.0 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S49 PF01343.18 AAL65089.1 - 7.4e-17 61.7 2.6 6.6e-10 39.1 1.3 2.3 2 0 0 2 2 2 2 Peptidase family S49 CLP_protease PF00574.23 AAL65089.1 - 1.8e-10 41.0 0.0 2.4e-08 34.1 0.0 2.3 2 0 0 2 2 2 1 Clp protease DUF948 PF06103.11 AAL65089.1 - 0.00093 19.4 0.6 0.0024 18.1 0.6 1.7 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) PSI_PsaH PF03244.14 AAL65089.1 - 0.082 12.4 0.2 0.52 9.8 0.1 2.2 2 0 0 2 2 2 0 Photosystem I reaction centre subunit VI L-fibroin PF05849.11 AAL65089.1 - 0.12 11.7 0.0 2.5 7.3 0.0 2.5 2 0 0 2 2 2 0 Fibroin light chain (L-fibroin) ECH_1 PF00378.20 AAL65089.1 - 0.27 10.5 1.0 3.5 6.8 0.0 2.2 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase Baculo_PEP_C PF04513.12 AAL65089.1 - 0.84 9.7 3.4 2.3 8.3 2.5 2.2 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus T4SS_CagC PF16943.5 AAL65089.1 - 0.96 9.7 3.2 0.96 9.6 0.1 2.5 3 0 0 3 3 3 0 Cag pathogenicity island, type IV secretory system Lactamase_B_3 PF13483.6 AAL65090.1 - 9e-06 25.7 0.0 1.8e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 AAL65090.1 - 0.00018 21.6 0.4 0.42 10.6 0.0 2.3 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AAL65090.1 - 0.00034 20.2 0.0 0.0011 18.6 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain PRA1 PF03208.19 AAL65091.1 - 0.29 10.7 5.2 1.4 8.6 5.2 2.0 1 1 0 1 1 1 0 PRA1 family protein FtsX PF02687.21 AAL65093.1 - 5.8e-12 45.9 1.2 5.8e-12 45.9 1.2 3.2 3 0 0 3 3 3 2 FtsX-like permease family MacB_PCD PF12704.7 AAL65093.1 - 3.2e-10 40.7 8.3 3.2e-10 40.7 8.3 2.9 3 0 0 3 3 3 1 MacB-like periplasmic core domain DUF2273 PF10031.9 AAL65093.1 - 0.08 13.0 0.6 0.08 13.0 0.6 3.5 5 0 0 5 5 5 0 Small integral membrane protein (DUF2273) LptF_LptG PF03739.14 AAL65093.1 - 0.42 9.4 9.3 0.11 11.3 5.2 2.0 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG Ribonuclease_P PF00825.18 AAL65094.1 - 0.0026 17.8 1.2 0.0033 17.5 1.2 1.3 1 0 0 1 1 1 1 Ribonuclease P AAA_5 PF07728.14 AAL65095.1 - 5.9e-26 91.1 0.0 8e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 AAL65095.1 - 0.0018 17.9 0.1 0.0047 16.5 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AAL65095.1 - 0.018 15.3 0.0 0.046 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 AAL65095.1 - 0.024 15.0 0.2 0.097 13.1 0.1 1.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 AAL65095.1 - 0.029 13.9 0.0 0.059 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 AAL65095.1 - 0.045 13.1 0.0 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 AAL65095.1 - 0.048 13.4 0.0 0.076 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 AAL65095.1 - 0.087 12.7 0.0 17 5.3 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 AAL65095.1 - 0.11 13.1 0.0 0.17 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 AAL65095.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Hpr_kinase_C PF07475.12 AAL65095.1 - 0.13 11.7 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA PF00004.29 AAL65095.1 - 0.15 12.5 0.0 0.3 11.5 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 AAL65095.1 - 0.16 11.1 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain DEAD PF00270.29 AAL65095.1 - 0.21 11.3 0.0 0.21 11.3 0.0 1.4 1 1 0 1 1 1 0 DEAD/DEAH box helicase # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Pyrobaculum_aerophilum_str._IM2-ASM722v1/GCA_000007225.1_ASM722v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Pyrobaculum_aerophilum_str._IM2-ASM722v1/GCA_000007225.1_ASM722v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Pyrobaculum_aerophilum_str._IM2-ASM722v1/GCA_000007225.1_ASM722v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Pyrobaculum_aerophilum_str._IM2-ASM722v1/GCA_000007225.1_ASM722v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 04:06:18 2019 # [ok]