# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- DUF1190 PF06693.11 AAZ32960.1 - 1e-33 117.0 10.5 6.6e-33 114.4 10.5 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1190) HD_4 PF13328.6 AAZ32961.1 - 4.5e-09 36.2 2.5 1e-06 28.6 0.2 2.1 2 0 0 2 2 2 2 HD domain DprA_WH PF17782.1 AAZ32961.1 - 0.07 13.3 0.6 1.2 9.3 0.2 2.2 2 0 0 2 2 2 0 DprA winged helix domain Phage_holin_3_1 PF05106.12 AAZ32962.1 - 2.1e-29 101.8 0.2 2.3e-29 101.7 0.2 1.0 1 0 0 1 1 1 1 Phage holin family (Lysis protein S) Phage_holin_3_3 PF16083.5 AAZ32962.1 - 1.6e-06 28.1 2.5 6.1e-06 26.3 2.0 1.9 1 1 1 2 2 2 1 LydA holin phage, holin superfamily III DUF3021 PF11457.8 AAZ32962.1 - 0.0083 16.5 0.5 0.0099 16.2 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3021) FtsK_4TM PF13491.6 AAZ32962.1 - 0.0091 15.7 1.0 0.011 15.4 1.0 1.1 1 0 0 1 1 1 1 4TM region of DNA translocase FtsK/SpoIIIE RecO_C PF02565.15 AAZ32964.1 - 4.8e-21 75.2 0.9 7.4e-21 74.6 0.9 1.3 1 0 0 1 1 1 1 Recombination protein O C terminal RecO_N PF11967.8 AAZ32964.1 - 7.9e-15 54.6 0.0 1.2e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Recombination protein O N terminal HDOD PF08668.12 AAZ32965.1 - 3.6e-45 153.9 0.0 5.1e-45 153.4 0.0 1.2 1 0 0 1 1 1 1 HDOD domain Lyase_aromatic PF00221.19 AAZ32967.1 - 3.4e-157 523.8 3.1 3.9e-157 523.7 3.1 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase TetR_C_33 PF13305.6 AAZ32968.1 - 9e-12 45.7 0.2 3.3e-11 43.9 0.0 1.8 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 AAZ32968.1 - 3.8e-06 26.6 0.0 8.4e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family MFS_1 PF07690.16 AAZ32969.1 - 7.9e-30 104.0 47.5 7.9e-30 104.0 47.5 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 AAZ32969.1 - 5.1e-22 78.3 5.9 5.1e-22 78.3 5.9 2.3 1 1 1 2 2 2 1 Sugar (and other) transporter Cu-oxidase_3 PF07732.15 AAZ32970.1 - 7.4e-36 122.8 0.0 3.9e-33 114.0 0.0 3.1 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 AAZ32970.1 - 4.7e-35 120.3 0.3 2.6e-26 92.0 0.1 4.0 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 AAZ32970.1 - 4.8e-10 39.8 0.0 0.00018 21.6 0.0 3.5 3 1 0 3 3 3 3 Multicopper oxidase MFS_1 PF07690.16 AAZ32971.1 - 1.1e-37 129.8 79.0 9.4e-29 100.4 43.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 AAZ32971.1 - 1.6e-09 37.1 26.9 3.2e-09 36.1 26.9 1.5 1 1 0 1 1 1 1 MFS_1 like family MFS_2 PF13347.6 AAZ32971.1 - 0.1 11.1 37.4 12 4.3 37.4 2.7 1 1 0 1 1 1 0 MFS/sugar transport protein Nuc_H_symport PF03825.16 AAZ32971.1 - 0.33 9.9 29.5 0.84 8.6 29.5 1.8 1 1 0 1 1 1 0 Nucleoside H+ symporter HemY_N PF07219.13 AAZ32972.1 - 1.6e-26 92.6 6.8 1.6e-26 92.6 6.8 3.4 4 1 0 5 5 4 1 HemY protein N-terminus TPR_19 PF14559.6 AAZ32972.1 - 1.3e-12 48.0 22.6 0.00054 20.4 8.5 4.8 3 2 1 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.6 AAZ32972.1 - 6.4e-09 35.9 33.8 0.19 12.6 3.5 7.4 2 2 5 7 7 7 4 Tetratricopeptide repeat TPR_4 PF07721.14 AAZ32972.1 - 5.9e-05 23.3 32.5 0.097 13.4 0.9 7.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 AAZ32972.1 - 0.00012 21.9 17.8 1.4 9.2 1.5 6.2 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 AAZ32972.1 - 0.00028 20.7 22.2 0.22 11.6 0.1 6.6 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 AAZ32972.1 - 0.00033 20.9 28.7 0.025 14.9 6.1 5.8 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 AAZ32972.1 - 0.002 18.8 30.2 0.056 14.1 4.4 5.8 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 AAZ32972.1 - 0.005 16.9 6.5 0.89 9.9 0.2 5.1 4 1 1 5 5 5 1 Tetratricopeptide repeat DUF2989 PF11207.8 AAZ32972.1 - 0.014 15.2 0.3 0.033 14.0 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2989) HrpB1_HrpK PF09613.10 AAZ32972.1 - 0.032 13.8 6.3 0.87 9.2 0.1 4.0 2 1 2 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) FAT PF02259.23 AAZ32972.1 - 0.061 12.5 1.3 0.11 11.6 0.4 1.9 2 1 0 2 2 2 0 FAT domain TPR_6 PF13174.6 AAZ32972.1 - 0.075 13.7 18.4 1.1 10.1 0.9 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat Coatomer_E PF04733.14 AAZ32972.1 - 0.076 12.4 1.2 0.41 10.0 0.1 2.5 3 1 0 3 3 3 0 Coatomer epsilon subunit TPR_1 PF00515.28 AAZ32972.1 - 1.7 8.6 7.2 2.7 8.0 0.7 4.0 4 1 1 5 5 4 0 Tetratricopeptide repeat DUF2976 PF11190.8 AAZ32972.1 - 2.5 8.0 5.0 4.3 7.2 5.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) DUF983 PF06170.12 AAZ32972.1 - 3.1 8.3 4.5 5.5 7.5 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF983) DUF5325 PF17259.2 AAZ32972.1 - 4.9 7.1 7.7 0.29 11.0 2.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5325) TPR_9 PF13371.6 AAZ32972.1 - 7.3 6.8 25.8 0.72 10.0 0.3 4.4 3 1 2 5 5 5 0 Tetratricopeptide repeat Cellulase PF00150.18 AAZ32973.1 - 1.8e-16 60.4 0.1 2.3e-16 60.0 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF2723 PF11028.8 AAZ32974.1 - 3.7e-05 23.7 7.3 3.7e-05 23.7 7.3 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2723) NDUF_B12 PF08122.12 AAZ32974.1 - 0.13 12.3 0.2 0.48 10.5 0.2 1.9 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B12 subunit family SCP2 PF02036.17 AAZ32975.1 - 0.0018 18.8 0.2 0.0024 18.3 0.2 1.2 1 0 0 1 1 1 1 SCP-2 sterol transfer family Adenine_glyco PF03352.13 AAZ32976.1 - 1.6e-69 233.2 0.0 1.9e-69 232.9 0.0 1.0 1 0 0 1 1 1 1 Methyladenine glycosylase CYTH PF01928.21 AAZ32976.1 - 0.14 12.1 0.0 0.5 10.3 0.0 1.7 2 0 0 2 2 2 0 CYTH domain DUF5510 PF17629.2 AAZ32978.1 - 0.0094 15.9 2.0 0.054 13.4 0.0 2.7 2 0 0 2 2 2 1 Family of unknown function (DUF5510) HemolysinCabind PF00353.19 AAZ32979.1 - 1.6e-56 187.7 173.9 3.5e-09 36.5 17.6 14.1 9 4 8 17 17 17 14 RTX calcium-binding nonapeptide repeat (4 copies) Pectate_lyase_3 PF12708.7 AAZ32979.1 - 3.3e-31 108.8 12.0 3.3e-31 108.8 12.0 3.3 2 1 0 2 2 2 1 Pectate lyase superfamily protein Beta_helix PF13229.6 AAZ32979.1 - 1.3e-18 67.3 34.5 1.4e-12 47.8 14.0 4.6 3 2 2 5 5 5 2 Right handed beta helix region Peptidase_M10_C PF08548.11 AAZ32979.1 - 2.1e-10 40.8 56.3 0.00014 21.8 0.4 7.6 3 2 2 5 5 5 4 Peptidase M10 serralysin C terminal He_PIG PF05345.12 AAZ32979.1 - 1.2e-09 38.2 8.0 3.6e-09 36.6 3.5 3.5 2 0 0 2 2 2 1 Putative Ig domain End_N_terminal PF12218.8 AAZ32979.1 - 0.0087 15.7 1.4 0.069 12.9 1.4 2.7 1 0 0 1 1 1 1 N terminal extension of bacteriophage endosialidase SulA PF03846.14 AAZ32980.1 - 3.6e-09 36.6 0.1 4.9e-09 36.1 0.1 1.2 1 0 0 1 1 1 1 Cell division inhibitor SulA cobW PF02492.19 AAZ32981.1 - 1.8e-35 122.1 0.0 2.3e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 AAZ32981.1 - 2e-06 27.0 0.0 0.001 18.1 0.0 2.1 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 AAZ32981.1 - 0.05 14.1 0.0 0.061 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AAZ32981.1 - 0.061 13.9 0.0 0.092 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 AAZ32981.1 - 0.085 12.9 0.0 0.095 12.8 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_2 PF07724.14 AAZ32981.1 - 0.12 12.5 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.12 AAZ32981.1 - 0.19 11.0 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Transposase_mut PF00872.18 AAZ32982.1 - 8.4e-64 215.8 0.0 9.5e-64 215.6 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ32982.1 - 2.8e-05 24.5 0.0 6.5e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 MULE transposase domain DUF4844 PF16133.5 AAZ32982.1 - 0.092 13.3 0.0 0.22 12.1 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4844) Nramp PF01566.18 AAZ32983.1 - 2.8e-45 154.8 22.0 3.4e-45 154.6 22.0 1.1 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Flg_hook PF02120.16 AAZ32984.1 - 8.6e-06 25.6 0.0 1.4e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Flagellar hook-length control protein FliK DUF3488 PF11992.8 AAZ32985.1 - 3.2e-91 305.6 6.0 4.7e-91 305.1 6.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3488) Transglut_core PF01841.19 AAZ32985.1 - 2.7e-22 79.3 0.1 5e-22 78.5 0.1 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF4129 PF13559.6 AAZ32985.1 - 2.3e-09 37.4 4.5 2.3e-09 37.4 4.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4129) Transglut_core3 PF13471.6 AAZ32985.1 - 0.0004 20.3 3.0 0.0027 17.6 0.1 2.7 2 0 0 2 2 2 1 Transglutaminase-like superfamily RimK PF08443.11 AAZ32986.1 - 1.7e-67 226.7 0.0 2.2e-67 226.3 0.0 1.1 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Rimk_N PF18030.1 AAZ32986.1 - 1.2e-45 153.9 0.0 2e-45 153.1 0.0 1.4 1 0 0 1 1 1 1 RimK PreATP-grasp domain GSH-S_ATP PF02955.16 AAZ32986.1 - 6.3e-17 61.5 0.1 1e-16 60.9 0.1 1.3 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATPgrasp_ST PF14397.6 AAZ32986.1 - 3.6e-07 29.7 0.0 0.0091 15.3 0.0 2.6 1 1 1 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 AAZ32986.1 - 7.7e-07 29.3 0.0 1.5e-06 28.4 0.0 1.4 1 1 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 AAZ32986.1 - 0.00011 21.8 0.1 0.0013 18.3 0.1 2.1 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_YheCD PF14398.6 AAZ32986.1 - 0.0012 18.2 0.0 0.054 12.7 0.0 2.8 1 1 0 1 1 1 1 YheC/D like ATP-grasp TTL PF03133.15 AAZ32986.1 - 0.19 10.8 0.0 4.1 6.4 0.0 2.2 2 0 0 2 2 2 0 Tubulin-tyrosine ligase family Polyketide_cyc PF03364.20 AAZ32987.1 - 5.1e-33 114.1 0.0 5.9e-33 113.8 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 AAZ32987.1 - 5.4e-07 30.0 0.0 6.4e-07 29.7 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Sigma70_r4_2 PF08281.12 AAZ32988.1 - 8.4e-14 51.0 0.0 1.4e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 AAZ32988.1 - 3.9e-13 49.0 0.4 6.6e-13 48.2 0.4 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 AAZ32988.1 - 1.9e-07 30.5 0.0 3.9e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_24 PF13412.6 AAZ32988.1 - 0.0032 17.0 0.0 0.0059 16.1 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Sigma70_ECF PF07638.11 AAZ32988.1 - 0.0075 16.2 0.0 0.011 15.7 0.0 1.3 1 1 0 1 1 1 1 ECF sigma factor HTH_3 PF01381.22 AAZ32988.1 - 0.0091 16.0 0.0 0.092 12.8 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix HTH_23 PF13384.6 AAZ32988.1 - 0.019 14.8 0.0 0.064 13.1 0.0 2.0 1 1 1 2 2 2 0 Homeodomain-like domain HTH_38 PF13936.6 AAZ32988.1 - 0.026 14.3 0.0 0.08 12.7 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 AAZ32988.1 - 0.036 13.5 0.0 0.072 12.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 MarR_2 PF12802.7 AAZ32988.1 - 0.046 13.6 0.0 0.11 12.5 0.0 1.6 2 0 0 2 2 2 0 MarR family Phage_terminase PF10668.9 AAZ32988.1 - 0.068 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Phage terminase small subunit HTH_10 PF04967.12 AAZ32988.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain KORA PF16509.5 AAZ32988.1 - 0.13 12.6 0.0 0.33 11.2 0.0 1.6 2 0 0 2 2 2 0 TrfB plasmid transcriptional repressor GerE PF00196.19 AAZ32988.1 - 0.14 11.7 0.0 0.33 10.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family BPD_transp_1 PF00528.22 AAZ32989.1 - 8.1e-18 64.8 14.0 8.1e-18 64.8 14.0 1.4 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component DUF2070 PF09843.9 AAZ32989.1 - 4.8 5.3 10.7 6.6 4.9 10.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) FCD PF07729.12 AAZ32990.1 - 1.1e-22 80.8 8.0 1.6e-22 80.2 8.0 1.3 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 AAZ32990.1 - 4e-18 64.8 0.4 1.5e-17 63.0 0.3 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_Crp_2 PF13545.6 AAZ32990.1 - 7.3e-05 22.7 0.0 0.00017 21.5 0.0 1.6 1 1 0 1 1 1 1 Crp-like helix-turn-helix domain MarR_2 PF12802.7 AAZ32990.1 - 0.001 18.9 0.6 0.0043 16.9 0.2 2.1 2 0 0 2 2 2 1 MarR family HTH_IclR PF09339.10 AAZ32990.1 - 0.0053 16.5 0.3 0.14 12.0 0.1 2.4 2 0 0 2 2 2 1 IclR helix-turn-helix domain Fe_dep_repress PF01325.19 AAZ32990.1 - 0.012 15.8 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_24 PF13412.6 AAZ32990.1 - 0.016 14.8 0.4 0.38 10.4 0.1 2.5 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding HTH_36 PF13730.6 AAZ32990.1 - 0.02 14.8 0.0 0.047 13.7 0.0 1.7 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_11 PF08279.12 AAZ32990.1 - 0.027 14.4 0.0 0.061 13.3 0.0 1.6 1 0 0 1 1 1 0 HTH domain TrmB PF01978.19 AAZ32990.1 - 0.033 14.1 0.0 0.06 13.2 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.20 AAZ32990.1 - 0.065 13.6 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator LexA_DNA_bind PF01726.16 AAZ32990.1 - 0.08 12.7 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 LexA DNA binding domain Transpeptidase PF00905.22 AAZ32991.1 - 1.6e-76 257.4 0.0 3.8e-76 256.2 0.0 1.5 2 0 0 2 2 2 1 Penicillin binding protein transpeptidase domain PBP_dimer PF03717.15 AAZ32991.1 - 1.2e-42 146.3 0.0 2e-42 145.6 0.0 1.4 1 0 0 1 1 1 1 Penicillin-binding Protein dimerisation domain Cyanate_lyase PF02560.14 AAZ32992.1 - 5.3e-33 112.7 0.0 8.1e-33 112.1 0.0 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.6 AAZ32992.1 - 0.00039 20.7 1.4 0.00088 19.6 1.6 1.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 AAZ32992.1 - 0.02 15.0 0.0 0.074 13.1 0.0 2.0 2 1 0 2 2 2 0 Helix-turn-helix NifU PF01106.17 AAZ32993.1 - 2e-19 69.5 0.1 3e-19 68.9 0.1 1.3 1 0 0 1 1 1 1 NifU-like domain Fe-S_biosyn PF01521.20 AAZ32993.1 - 6.4e-10 39.2 0.0 2.7e-09 37.2 0.0 2.0 2 1 0 2 2 2 1 Iron-sulphur cluster biosynthesis MFS_1 PF07690.16 AAZ32994.1 - 3.8e-34 118.2 57.3 1.3e-26 93.3 35.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AAZ32994.1 - 8.1e-33 113.9 33.8 1.1e-24 87.1 7.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 AAZ32994.1 - 3.9e-10 39.1 4.2 1.1e-05 24.5 0.1 3.8 1 1 3 4 4 4 2 MFS_1 like family AzlD PF05437.12 AAZ32994.1 - 0.0092 16.1 0.5 0.0092 16.1 0.5 4.0 3 1 1 4 4 4 1 Branched-chain amino acid transport protein (AzlD) Patatin PF01734.22 AAZ32995.1 - 9.7e-20 71.6 2.4 2.7e-19 70.1 2.4 1.8 1 1 0 1 1 1 1 Patatin-like phospholipase Transposase_mut PF00872.18 AAZ32996.1 - 2.8e-117 391.8 0.0 3.4e-117 391.5 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ32996.1 - 7.7e-05 23.0 0.0 0.00021 21.6 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain DUF4844 PF16133.5 AAZ32996.1 - 0.23 12.0 0.0 0.55 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) SBP_bac_5 PF00496.22 AAZ32997.1 - 2.7e-98 329.4 5.5 3.3e-98 329.1 5.5 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle CcmD PF04995.14 AAZ32998.1 - 3e-15 56.0 0.5 3.5e-15 55.8 0.5 1.1 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) TP_methylase PF00590.20 AAZ32999.1 - 1.5e-17 64.2 0.2 5.4e-17 62.4 0.2 1.8 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases PCMT PF01135.19 AAZ32999.1 - 0.054 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.15 AAZ32999.1 - 0.2 11.3 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Peptidase_S24 PF00717.23 AAZ33000.1 - 9.4e-17 60.7 0.0 1.5e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Acetyltransf_1 PF00583.25 AAZ33001.1 - 6.2e-12 45.8 0.1 7.5e-12 45.5 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AAZ33001.1 - 2.4e-11 43.7 0.0 3e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAZ33001.1 - 1.4e-09 38.2 0.1 1.9e-09 37.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAZ33001.1 - 3.9e-08 33.1 0.0 5.5e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 AAZ33001.1 - 0.00017 21.7 0.0 0.0072 16.4 0.0 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AAZ33001.1 - 0.00081 19.5 0.0 0.001 19.2 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AAZ33001.1 - 0.012 16.3 0.0 0.051 14.3 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 AAZ33001.1 - 0.1 12.3 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain BPD_transp_1 PF00528.22 AAZ33003.1 - 1.9e-11 44.0 15.0 1.9e-11 44.0 15.0 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 AAZ33004.1 - 5.8e-35 120.8 0.0 8e-35 120.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 AAZ33004.1 - 2.8e-18 66.2 0.8 6.8e-18 65.0 0.8 1.7 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 AAZ33004.1 - 1.1e-06 28.7 0.0 0.0043 16.9 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 AAZ33004.1 - 1.2e-06 28.9 0.5 1.1e-05 25.7 0.5 2.0 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 AAZ33004.1 - 1.5e-06 27.9 0.0 2.2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AAZ33004.1 - 0.00083 19.8 0.4 0.0012 19.3 0.4 1.4 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 AAZ33004.1 - 0.0016 18.2 0.1 0.025 14.3 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein RsgA_GTPase PF03193.16 AAZ33004.1 - 0.0029 17.6 0.2 0.0058 16.6 0.2 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 AAZ33004.1 - 0.0047 16.6 0.0 0.0097 15.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AAZ33004.1 - 0.0078 16.7 0.0 0.012 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 AAZ33004.1 - 0.011 15.7 0.1 0.047 13.6 0.0 2.0 2 0 0 2 2 2 0 NACHT domain Mg_chelatase PF01078.21 AAZ33004.1 - 0.017 14.5 0.2 0.071 12.5 0.0 1.9 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.23 AAZ33004.1 - 0.023 14.7 0.0 0.05 13.7 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA PF00004.29 AAZ33004.1 - 0.029 14.8 0.1 0.12 12.8 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 AAZ33004.1 - 0.047 13.1 0.2 4.6 6.6 0.1 2.3 1 1 1 2 2 2 0 Bacterial TniB protein PRK PF00485.18 AAZ33004.1 - 0.051 13.3 0.0 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_15 PF13175.6 AAZ33004.1 - 0.065 12.9 0.0 0.085 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 AAZ33004.1 - 0.07 13.3 0.1 0.12 12.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 AAZ33004.1 - 0.081 13.3 0.0 0.2 12.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_13 PF13166.6 AAZ33004.1 - 0.12 11.0 0.0 1.9 7.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 AAZ33004.1 - 0.14 11.3 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Septin PF00735.18 AAZ33004.1 - 0.14 11.4 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_25 PF13481.6 AAZ33004.1 - 0.22 11.1 0.5 0.54 9.8 0.2 1.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 AAZ33004.1 - 0.22 11.2 0.0 0.38 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 AAZ33004.1 - 0.26 10.4 0.4 0.45 9.6 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain Multi_Drug_Res PF00893.19 AAZ33005.1 - 1.7e-15 57.5 4.4 2.4e-15 57.0 4.4 1.2 1 0 0 1 1 1 1 Small Multidrug Resistance protein EamA PF00892.20 AAZ33005.1 - 0.00046 20.4 11.3 0.00054 20.1 11.3 1.1 1 0 0 1 1 1 1 EamA-like transporter family Tmemb_170 PF10190.9 AAZ33005.1 - 0.012 16.0 4.7 0.045 14.1 2.0 2.5 1 1 0 1 1 1 0 Putative transmembrane protein 170 EmrE PF13536.6 AAZ33005.1 - 0.028 14.0 5.1 0.034 13.7 5.1 1.1 1 0 0 1 1 1 0 Putative multidrug resistance efflux transporter DUF308 PF03729.13 AAZ33005.1 - 0.036 14.4 13.3 0.25 11.7 2.5 2.3 2 1 0 2 2 2 0 Short repeat of unknown function (DUF308) ThrE PF06738.12 AAZ33005.1 - 1.2 8.5 9.9 1.8 7.8 9.9 1.4 1 1 0 1 1 1 0 Putative threonine/serine exporter DUF202 PF02656.15 AAZ33005.1 - 4.4 7.8 11.0 9.6 6.7 2.5 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF202) zf-RING_7 PF02591.15 AAZ33006.1 - 0.062 13.5 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 C4-type zinc ribbon domain Glyoxalase PF00903.25 AAZ33007.1 - 5.5e-07 29.8 0.1 9.6e-07 29.0 0.1 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 AAZ33007.1 - 0.0089 16.3 0.1 0.013 15.8 0.1 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 AAZ33007.1 - 0.064 14.0 0.0 0.098 13.5 0.0 1.3 1 1 0 1 1 1 0 Glyoxalase-like domain RHS PF03527.14 AAZ33008.1 - 1.2e-18 66.6 0.1 8e-16 57.5 0.0 2.7 2 0 0 2 2 2 2 RHS protein RHS_repeat PF05593.14 AAZ33008.1 - 1.4e-12 47.9 2.6 0.0029 18.1 0.1 5.7 4 1 2 6 6 6 5 RHS Repeat DUF4595 PF15283.6 AAZ33008.1 - 0.031 14.4 3.8 0.26 11.3 3.7 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4595) with porin-like fold TctB PF07331.11 AAZ33009.1 - 3e-20 72.9 14.4 3.7e-20 72.6 14.4 1.0 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter TctB family PHO4 PF01384.20 AAZ33009.1 - 0.73 8.8 2.9 1 8.4 2.9 1.2 1 0 0 1 1 1 0 Phosphate transporter family Zn_protease PF05618.11 AAZ33010.1 - 1.3e-46 157.9 0.0 1.5e-46 157.7 0.0 1.0 1 0 0 1 1 1 1 Putative ATP-dependant zinc protease GreA_GreB PF01272.19 AAZ33011.1 - 6.4e-28 96.5 3.5 1e-27 95.8 3.5 1.3 1 0 0 1 1 1 1 Transcription elongation factor, GreA/GreB, C-term GreA_GreB_N PF03449.15 AAZ33011.1 - 1.9e-27 95.2 0.6 3e-27 94.5 0.6 1.3 1 0 0 1 1 1 1 Transcription elongation factor, N-terminal ABC_tran PF00005.27 AAZ33012.1 - 8.1e-30 104.1 0.0 1.2e-29 103.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAZ33012.1 - 5.6e-08 32.9 0.0 0.0016 18.3 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AAZ33012.1 - 5.4e-06 26.9 0.2 1.3e-05 25.6 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 AAZ33012.1 - 0.00069 19.8 0.0 0.0033 17.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AAZ33012.1 - 0.00096 19.1 0.2 0.0017 18.3 0.0 1.5 2 0 0 2 2 2 1 RsgA GTPase Rad17 PF03215.15 AAZ33012.1 - 0.0025 17.7 0.0 0.0046 16.9 0.0 1.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_29 PF13555.6 AAZ33012.1 - 0.0053 16.5 0.1 0.012 15.3 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 AAZ33012.1 - 0.0081 16.6 0.0 0.035 14.5 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AAZ33012.1 - 0.0095 16.2 1.4 0.04 14.2 0.4 2.3 2 1 0 2 2 2 1 AAA domain ABC_ATPase PF09818.9 AAZ33012.1 - 0.033 13.0 0.1 0.52 9.0 0.0 2.4 2 1 0 2 2 2 0 Predicted ATPase of the ABC class AAA_23 PF13476.6 AAZ33012.1 - 0.067 13.7 0.0 0.097 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 AAZ33012.1 - 0.067 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF4029 PF13221.6 AAZ33012.1 - 0.08 13.6 0.0 0.15 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4029) NACHT PF05729.12 AAZ33012.1 - 0.087 12.7 0.0 0.21 11.5 0.0 1.6 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.22 AAZ33012.1 - 0.097 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_28 PF13521.6 AAZ33012.1 - 0.1 12.9 0.0 0.65 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 AAZ33012.1 - 0.14 12.7 0.0 0.43 11.1 0.0 1.8 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 AAZ33012.1 - 0.15 12.0 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) dTDP_sugar_isom PF00908.17 AAZ33013.1 - 2.9e-76 254.9 0.0 3.2e-76 254.7 0.0 1.0 1 0 0 1 1 1 1 dTDP-4-dehydrorhamnose 3,5-epimerase Isochorismatase PF00857.20 AAZ33014.1 - 1.2e-28 100.5 0.0 1.4e-28 100.3 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family Peripla_BP_3 PF13377.6 AAZ33015.1 - 6.6e-45 153.4 0.5 1.6e-43 148.9 1.1 2.1 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 AAZ33015.1 - 1.1e-31 110.4 0.0 1.4e-31 110.0 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_4 PF13407.6 AAZ33015.1 - 1.7e-18 67.2 0.0 2.6e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein domain LacI PF00356.21 AAZ33015.1 - 3.3e-17 62.0 0.3 6.9e-17 61.0 0.3 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family HTH_3 PF01381.22 AAZ33015.1 - 0.018 15.1 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix HTH_Tnp_ISL3 PF13542.6 AAZ33015.1 - 0.022 14.1 0.0 0.062 12.7 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 SEC-C PF02810.15 AAZ33016.1 - 4.5e-12 45.6 6.3 5.7e-12 45.3 6.3 1.2 1 0 0 1 1 1 1 SEC-C motif Polysacc_synt_C PF14667.6 AAZ33017.1 - 1.4e-10 41.3 4.5 1.4e-10 41.3 4.5 4.7 2 1 2 4 4 4 1 Polysaccharide biosynthesis C-terminal domain Polysacc_synt PF01943.17 AAZ33017.1 - 5.9e-07 29.1 20.0 1.4e-06 27.9 20.0 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Polysacc_synt_3 PF13440.6 AAZ33017.1 - 1.1e-06 28.2 12.7 1.1e-06 28.2 12.7 2.0 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein IncE PF17627.2 AAZ33017.1 - 0.53 10.3 5.0 0.75 9.8 0.4 2.7 2 0 0 2 2 2 0 Inclusion membrane protein E Phos_pyr_kin PF08543.12 AAZ33018.1 - 2e-69 233.7 0.0 2.4e-69 233.4 0.0 1.0 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 AAZ33018.1 - 0.064 12.5 0.0 0.15 11.4 0.0 1.6 1 1 0 1 1 1 0 pfkB family carbohydrate kinase HTH_Tnp_Tc3_2 PF01498.18 AAZ33019.1 - 0.0058 16.8 0.0 0.008 16.4 0.0 1.1 1 0 0 1 1 1 1 Transposase Sigma70_r2 PF04542.14 AAZ33020.1 - 4.5e-10 39.1 0.1 7.7e-10 38.4 0.1 1.3 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 AAZ33020.1 - 4.6e-09 35.8 0.0 7.9e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAZ33020.1 - 6.3e-09 35.2 0.0 1.5e-08 34.0 0.0 1.7 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_30 PF13556.6 AAZ33020.1 - 1.4e-05 24.7 0.0 3e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain DUF2089 PF09862.9 AAZ33020.1 - 0.00036 20.5 0.0 0.016 15.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2089) B2 PF11473.8 AAZ33020.1 - 0.065 13.0 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 RNA binding protein B2 TonB_dep_Rec PF00593.24 AAZ33021.1 - 1.5e-51 176.8 44.9 1.5e-51 176.8 44.9 2.0 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 AAZ33021.1 - 6e-26 91.1 4.2 1.8e-25 89.6 4.2 1.8 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain Big_2 PF02368.18 AAZ33022.1 - 0.0001 22.1 0.5 0.0001 22.1 0.5 2.7 2 1 0 2 2 2 1 Bacterial Ig-like domain (group 2) SprB PF13573.6 AAZ33022.1 - 0.095 12.5 0.2 0.095 12.5 0.2 3.9 4 0 0 4 4 4 0 SprB repeat Lactamase_B PF00753.27 AAZ33023.1 - 1.2e-18 67.8 0.1 1.7e-18 67.3 0.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AAZ33023.1 - 2.6e-07 30.3 0.2 4e-07 29.7 0.2 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain MerR-DNA-bind PF09278.11 AAZ33024.1 - 1.9e-21 76.3 4.6 3.6e-21 75.5 4.6 1.5 1 0 0 1 1 1 1 MerR, DNA binding MerR_1 PF13411.6 AAZ33024.1 - 1.1e-16 60.7 0.0 2e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 AAZ33024.1 - 2.2e-15 56.1 0.1 3.7e-15 55.4 0.1 1.4 1 0 0 1 1 1 1 MerR family regulatory protein DUF5082 PF16888.5 AAZ33024.1 - 0.013 15.8 0.2 0.02 15.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) Death PF00531.22 AAZ33024.1 - 0.021 15.0 0.3 0.071 13.3 0.3 1.9 1 1 0 1 1 1 0 Death domain HopW1-1 PF15457.6 AAZ33024.1 - 0.034 13.4 0.2 0.044 13.1 0.2 1.1 1 0 0 1 1 1 0 Type III T3SS secreted effector HopW1-1/HopPmaA AbiEi_4 PF13338.6 AAZ33024.1 - 0.042 14.0 0.1 0.19 11.9 0.0 2.1 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin NMN_transporter PF04973.12 AAZ33026.1 - 6.3e-53 179.3 21.8 7e-53 179.2 21.8 1.0 1 0 0 1 1 1 1 Nicotinamide mononucleotide transporter Urate_ox_N PF06181.11 AAZ33027.1 - 3.5e-126 420.5 8.9 4.2e-126 420.3 8.9 1.1 1 0 0 1 1 1 1 Urate oxidase N-terminal Cytochrome-c551 PF10643.9 AAZ33027.1 - 0.027 14.0 0.5 0.054 13.1 0.0 1.9 2 0 0 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 Haem_bd PF14376.6 AAZ33027.1 - 0.032 14.2 0.1 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 Haem-binding domain DUF4131 PF13567.6 AAZ33027.1 - 0.51 10.0 8.0 1.5 8.5 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) PrgI PF12666.7 AAZ33027.1 - 7.1 7.4 6.0 12 6.7 0.2 3.2 3 0 0 3 3 3 0 PrgI family protein Gly-zipper_YMGG PF13441.6 AAZ33028.1 - 2.6e-10 39.9 56.7 1.8e-05 24.4 22.0 2.4 2 0 0 2 2 2 2 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 AAZ33028.1 - 8.2e-10 38.5 60.5 4.8e-07 29.7 23.2 2.4 3 0 0 3 3 3 2 Glycine zipper Rick_17kDa_Anti PF05433.15 AAZ33028.1 - 5.7e-05 22.9 70.2 0.00081 19.2 28.1 2.7 2 1 0 3 3 3 2 Glycine zipper 2TM domain CheW PF01584.19 AAZ33029.1 - 3.3e-26 91.5 0.0 3.9e-26 91.3 0.0 1.1 1 0 0 1 1 1 1 CheW-like domain MFS_1_like PF12832.7 AAZ33030.1 - 2.5e-80 270.2 32.5 3.3e-80 269.8 32.5 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 AAZ33030.1 - 3.4e-17 62.4 62.9 1.2e-12 47.4 30.1 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 AAZ33030.1 - 1.3e-12 47.4 27.9 1.7e-12 47.0 27.9 1.1 1 0 0 1 1 1 1 Nucleoside H+ symporter RHS_repeat PF05593.14 AAZ33031.1 - 8.2e-08 32.6 2.4 0.00036 21.0 0.3 2.2 2 0 0 2 2 2 2 RHS Repeat SBP_bac_8 PF13416.6 AAZ33032.1 - 3.6e-44 151.7 13.6 5.2e-44 151.2 13.6 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AAZ33032.1 - 2.2e-15 56.8 3.0 3.4e-15 56.1 3.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AAZ33032.1 - 9.1e-12 45.6 15.7 1.4e-11 44.9 15.7 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 AAZ33032.1 - 0.00027 20.8 1.2 0.00077 19.3 1.2 2.0 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SurE PF01975.17 AAZ33033.1 - 4e-55 186.6 0.0 4.8e-55 186.4 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE DUF4096 PF13340.6 AAZ33034.1 - 5.8e-25 87.3 0.4 1.5e-24 86.0 0.4 1.8 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1 PF01609.21 AAZ33034.1 - 3.2e-14 53.1 0.0 5.7e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AAZ33034.1 - 7.2e-10 39.1 0.2 2.1e-09 37.6 0.2 1.9 1 0 0 1 1 1 1 Transposase DDE domain HTH_Tnp_Tc3_2 PF01498.18 AAZ33034.1 - 0.061 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Transposase Polysacc_synt_2 PF02719.15 AAZ33036.1 - 2.3e-127 424.2 0.1 3.2e-127 423.7 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 AAZ33036.1 - 2e-14 53.6 0.1 1.4e-13 50.9 0.1 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AAZ33036.1 - 2.5e-10 40.3 0.0 9.3e-10 38.4 0.1 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 AAZ33036.1 - 5.4e-08 32.2 0.0 9.1e-08 31.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 AAZ33036.1 - 8.5e-08 31.6 0.3 7.7e-07 28.5 0.3 2.5 1 1 0 1 1 1 1 RmlD substrate binding domain CoA_binding_3 PF13727.6 AAZ33036.1 - 1.8e-06 28.1 0.3 1.8e-06 28.1 0.3 2.6 2 1 1 3 3 3 1 CoA-binding domain adh_short PF00106.25 AAZ33036.1 - 0.0006 19.3 0.1 0.0011 18.5 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Ldh_1_N PF00056.23 AAZ33036.1 - 0.004 17.2 0.0 4.1 7.5 0.0 2.4 2 0 0 2 2 2 2 lactate/malate dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 AAZ33036.1 - 0.0055 15.9 1.3 0.024 13.8 1.2 2.1 1 1 0 1 1 1 1 Male sterility protein ThiF PF00899.21 AAZ33036.1 - 0.011 15.1 0.3 0.42 9.9 0.0 2.5 3 0 0 3 3 3 0 ThiF family GFO_IDH_MocA PF01408.22 AAZ33036.1 - 0.062 14.1 0.0 0.47 11.3 0.0 2.4 3 1 0 3 3 2 0 Oxidoreductase family, NAD-binding Rossmann fold ribosomal_L24 PF17136.4 AAZ33037.1 - 6.1e-25 87.4 0.7 9.3e-25 86.8 0.7 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 AAZ33037.1 - 1.3e-05 25.0 1.7 3e-05 23.8 1.7 1.7 1 0 0 1 1 1 1 KOW motif Sulfate_transp PF00916.20 AAZ33038.1 - 2.4e-48 164.8 37.7 1.3e-46 159.1 33.0 2.8 1 1 1 2 2 2 1 Sulfate permease family STAS_2 PF13466.6 AAZ33038.1 - 3.5e-11 43.3 0.5 9.6e-11 41.9 0.1 2.0 2 0 0 2 2 2 1 STAS domain STAS PF01740.21 AAZ33038.1 - 1.2e-10 41.1 0.0 2e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 AAZ33038.1 - 4.1e-06 27.2 43.9 1.4e-05 25.5 4.6 4.2 3 1 1 4 4 4 3 Molybdate transporter of MFS superfamily RDD PF06271.12 AAZ33039.1 - 3.7e-20 72.6 4.8 4.9e-20 72.2 4.8 1.1 1 0 0 1 1 1 1 RDD family Muted PF14942.6 AAZ33040.1 - 0.072 13.4 7.6 0.086 13.2 7.6 1.0 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein CENP-H PF05837.12 AAZ33040.1 - 0.08 13.4 10.2 0.093 13.2 10.2 1.1 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF883 PF05957.13 AAZ33040.1 - 0.11 13.1 12.2 0.11 13.2 11.6 1.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) FAM176 PF14851.6 AAZ33040.1 - 0.15 11.7 4.5 0.18 11.5 4.5 1.1 1 0 0 1 1 1 0 FAM176 family VitK2_biosynth PF02621.14 AAZ33040.1 - 0.16 11.5 2.0 0.18 11.3 2.0 1.1 1 0 0 1 1 1 0 Menaquinone biosynthesis YtxH PF12732.7 AAZ33040.1 - 0.25 11.9 11.5 0.38 11.3 11.5 1.4 1 1 0 1 1 1 0 YtxH-like protein Oleosin PF01277.17 AAZ33040.1 - 0.31 10.8 3.1 0.19 11.5 1.0 1.6 1 1 1 2 2 2 0 Oleosin Methyltransf_32 PF13679.6 AAZ33040.1 - 0.34 10.9 6.3 0.4 10.6 6.3 1.1 1 0 0 1 1 1 0 Methyltransferase domain DUF2570 PF10828.8 AAZ33040.1 - 0.4 10.5 8.9 0.43 10.4 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) DUF4820 PF16091.5 AAZ33040.1 - 0.5 9.7 6.7 0.53 9.6 6.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF3450 PF11932.8 AAZ33040.1 - 0.65 9.3 15.3 1.1 8.5 15.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF1180 PF06679.12 AAZ33040.1 - 0.73 10.2 6.8 0.8 10.1 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Presenilin PF01080.17 AAZ33040.1 - 1 8.0 11.1 1 8.0 11.1 1.0 1 0 0 1 1 1 0 Presenilin PIP5K PF01504.18 AAZ33040.1 - 1.1 8.5 5.1 1.2 8.3 5.1 1.0 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Gti1_Pac2 PF09729.9 AAZ33040.1 - 1.4 9.0 7.7 1.6 8.8 7.7 1.0 1 0 0 1 1 1 0 Gti1/Pac2 family DUF2058 PF09831.9 AAZ33040.1 - 1.5 9.0 15.5 1.8 8.7 15.5 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) V_ATPase_I PF01496.19 AAZ33040.1 - 1.7 6.4 7.0 1.9 6.3 7.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RR_TM4-6 PF06459.12 AAZ33040.1 - 2.5 7.9 12.3 2.5 7.9 12.3 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CLN3 PF02487.17 AAZ33040.1 - 2.6 7.0 5.6 3.1 6.7 5.6 1.1 1 0 0 1 1 1 0 CLN3 protein ATP-synt_B PF00430.18 AAZ33040.1 - 2.8 8.1 22.5 3.3 7.8 22.5 1.1 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) TMPIT PF07851.13 AAZ33040.1 - 3 7.0 5.6 3.2 6.9 5.6 1.0 1 0 0 1 1 1 0 TMPIT-like protein CPSF100_C PF13299.6 AAZ33040.1 - 3.3 7.8 9.8 3.7 7.7 9.8 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Connexin PF00029.19 AAZ33040.1 - 3.7 7.3 5.1 3.9 7.2 5.1 1.1 1 0 0 1 1 1 0 Connexin Borrelia_P83 PF05262.11 AAZ33040.1 - 3.7 5.9 15.2 3.9 5.9 15.2 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein ALMT PF11744.8 AAZ33040.1 - 4.2 6.1 7.2 4.1 6.1 7.2 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter AIF_C PF14721.6 AAZ33040.1 - 4.3 7.7 8.3 5.5 7.3 8.3 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF913 PF06025.12 AAZ33040.1 - 4.5 6.1 8.7 4.4 6.2 8.7 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Kei1 PF08552.11 AAZ33040.1 - 4.7 7.1 9.2 5 6.9 9.2 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 SAPS PF04499.15 AAZ33040.1 - 4.9 5.8 9.4 4.9 5.8 9.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Neur_chan_memb PF02932.16 AAZ33040.1 - 5.6 6.9 6.1 5.7 6.9 6.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RNase_J_C PF17770.1 AAZ33040.1 - 5.8 8.0 5.7 5.5 8.1 4.8 1.4 1 1 0 1 1 1 0 Ribonuclease J C-terminal domain DDHD PF02862.17 AAZ33040.1 - 5.8 7.0 8.5 6.5 6.8 8.5 1.1 1 0 0 1 1 1 0 DDHD domain HisKA_3 PF07730.13 AAZ33040.1 - 6.5 7.4 8.8 1.2e+02 3.3 8.8 2.1 1 1 0 1 1 1 0 Histidine kinase Ureide_permease PF07168.11 AAZ33040.1 - 7 5.3 5.5 7.6 5.2 5.5 1.0 1 0 0 1 1 1 0 Ureide permease Alanine_zipper PF11839.8 AAZ33040.1 - 8.4 6.8 32.3 72 3.9 32.3 2.0 1 1 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein RNA_pol_Rpc4 PF05132.14 AAZ33040.1 - 8.5 6.8 12.4 11 6.5 12.4 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Glu_synthase PF01645.17 AAZ33041.1 - 5.2e-88 295.7 0.9 1.2e-80 271.5 1.5 2.0 2 0 0 2 2 2 2 Conserved region in glutamate synthase FMN_dh PF01070.18 AAZ33041.1 - 8.6e-17 61.2 3.7 2.7e-16 59.6 1.9 2.3 3 0 0 3 3 3 1 FMN-dependent dehydrogenase NMO PF03060.15 AAZ33041.1 - 3.9e-09 36.3 8.1 1.3e-08 34.6 7.0 2.0 1 1 1 2 2 2 1 Nitronate monooxygenase IMPDH PF00478.25 AAZ33041.1 - 4.8e-09 35.7 3.9 1.1e-08 34.5 3.9 1.5 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 AAZ33041.1 - 0.00012 21.7 0.1 0.00023 20.7 0.1 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein DHO_dh PF01180.21 AAZ33041.1 - 0.00013 21.3 0.3 0.00023 20.5 0.3 1.5 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase ThiG PF05690.14 AAZ33041.1 - 0.00021 20.7 0.6 0.00047 19.6 0.6 1.5 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG Glu_syn_central PF04898.14 AAZ33041.1 - 0.00091 18.8 0.1 0.0015 18.1 0.1 1.2 1 0 0 1 1 1 1 Glutamate synthase central domain QRPTase_C PF01729.19 AAZ33041.1 - 0.004 17.0 0.1 0.0082 15.9 0.1 1.4 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain G3P_antiterm PF04309.12 AAZ33041.1 - 0.013 14.9 0.5 0.023 14.1 0.5 1.4 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator PcrB PF01884.17 AAZ33041.1 - 0.061 12.8 3.0 0.27 10.7 1.2 2.2 1 1 1 2 2 2 0 PcrB family NanE PF04131.14 AAZ33041.1 - 0.1 11.8 0.4 1.8 7.7 0.3 2.3 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase DAP_epimerase PF01678.19 AAZ33043.1 - 3.9e-65 217.5 0.0 3.3e-32 111.2 0.0 2.1 2 0 0 2 2 2 2 Diaminopimelate epimerase PhzC-PhzF PF02567.16 AAZ33043.1 - 5.1e-06 26.2 0.0 9e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Endonuclease_NS PF01223.23 AAZ33044.1 - 2.4e-53 181.3 0.0 2.8e-53 181.1 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease FabA PF07977.13 AAZ33045.1 - 1.9e-52 176.6 0.0 2.2e-52 176.4 0.0 1.0 1 0 0 1 1 1 1 FabA-like domain rve PF00665.26 AAZ33046.1 - 4.2e-33 114.1 0.1 6.1e-33 113.5 0.1 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 AAZ33046.1 - 2.7e-11 43.1 0.8 5e-11 42.2 0.8 1.5 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 AAZ33046.1 - 7.5e-11 42.4 0.1 9.6e-11 42.1 0.1 1.1 1 0 0 1 1 1 1 DDE domain HTH_21 PF13276.6 AAZ33046.1 - 0.0011 19.1 0.5 0.0064 16.6 0.0 2.4 2 0 0 2 2 2 1 HTH-like domain rve_2 PF13333.6 AAZ33046.1 - 0.0015 18.7 0.0 0.0024 18.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Bac_surface_Ag PF01103.23 AAZ33047.1 - 2.3e-95 319.8 10.2 4e-95 319.0 10.2 1.4 1 0 0 1 1 1 1 Surface antigen POTRA PF07244.15 AAZ33047.1 - 4.6e-67 222.6 10.7 4.7e-17 62.3 0.3 5.4 5 0 0 5 5 5 5 Surface antigen variable number repeat POTRA_1 PF08478.10 AAZ33047.1 - 3.1e-10 40.2 0.1 0.011 16.0 0.0 4.7 4 0 0 4 4 4 2 POTRA domain, FtsQ-type POTRA_2 PF08479.11 AAZ33047.1 - 3e-07 30.2 2.3 0.74 9.7 0.1 5.1 5 0 0 5 5 5 3 POTRA domain, ShlB-type YqfD PF06898.11 AAZ33047.1 - 0.0028 16.5 0.0 0.0072 15.2 0.0 1.6 1 0 0 1 1 1 1 Putative stage IV sporulation protein YqfD ShlB PF03865.13 AAZ33047.1 - 0.032 13.7 2.4 0.56 9.6 4.2 2.1 2 1 0 2 2 2 0 Haemolysin secretion/activation protein ShlB/FhaC/HecB Transglut_core2 PF13369.6 AAZ33048.1 - 1.8e-32 112.1 0.2 2.8e-32 111.4 0.2 1.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily TPR_9 PF13371.6 AAZ33048.1 - 2.5e-10 40.4 5.5 6.8e-10 39.0 5.5 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 AAZ33048.1 - 0.04 14.2 1.2 0.12 12.6 1.2 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat HlyD_D23 PF16576.5 AAZ33049.1 - 1.3e-15 57.2 3.5 2e-15 56.6 3.5 1.2 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AAZ33049.1 - 7.2e-13 49.2 3.6 4.1e-10 40.3 0.7 2.7 2 0 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AAZ33049.1 - 4.8e-06 26.3 1.3 4.8e-06 26.3 1.3 3.3 4 0 0 4 4 4 1 Biotin-lipoyl like OEP PF02321.18 AAZ33049.1 - 0.032 14.0 7.9 0.21 11.3 8.6 2.0 2 0 0 2 2 2 0 Outer membrane efflux protein Biotin_lipoyl PF00364.22 AAZ33049.1 - 0.077 12.8 0.0 2.8 7.8 0.0 2.6 2 0 0 2 2 2 0 Biotin-requiring enzyme LPAM_2 PF13627.6 AAZ33049.1 - 3.4 7.6 5.7 7.5 6.5 5.7 1.6 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site DsrC PF04358.13 AAZ33050.1 - 3.7e-36 123.9 0.0 4.1e-36 123.8 0.0 1.0 1 0 0 1 1 1 1 DsrC like protein Asp_Glu_race PF01177.22 AAZ33052.1 - 2.8e-34 118.9 0.0 3.4e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase HPS3_C PF14763.6 AAZ33052.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3, C-terminal Phosphonate-bd PF12974.7 AAZ33053.1 - 5.3e-68 229.2 0.3 6e-68 229.0 0.3 1.0 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 AAZ33053.1 - 2.3e-11 43.6 0.1 5.8e-11 42.3 0.1 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1 PF09084.11 AAZ33053.1 - 7e-07 29.4 0.0 1e-06 28.9 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like GPP34 PF05719.11 AAZ33053.1 - 0.0037 17.3 0.0 0.0062 16.6 0.0 1.4 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) OpuAC PF04069.12 AAZ33053.1 - 0.0084 15.7 0.2 0.021 14.4 0.2 1.8 1 1 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system NMT1_3 PF16868.5 AAZ33053.1 - 0.044 13.2 0.0 0.057 12.8 0.0 1.2 1 0 0 1 1 1 0 NMT1-like family RNB PF00773.19 AAZ33054.1 - 4.1e-109 364.9 0.0 6.7e-109 364.2 0.0 1.3 1 0 0 1 1 1 1 RNB domain CSD2 PF17876.1 AAZ33054.1 - 4.3e-26 90.9 0.4 3.2e-23 81.7 0.5 2.7 2 0 0 2 2 2 2 Cold shock domain OB_RNB PF08206.11 AAZ33054.1 - 4.8e-22 77.4 6.4 9.6e-20 70.0 0.5 3.0 3 0 0 3 3 3 2 Ribonuclease B OB domain S1 PF00575.23 AAZ33054.1 - 4.2e-12 46.2 0.4 2.9e-11 43.5 0.1 2.5 2 0 0 2 2 2 1 S1 RNA binding domain HTH_12 PF08461.10 AAZ33054.1 - 2.7e-08 33.6 0.8 6.1e-08 32.5 0.3 1.9 2 0 0 2 2 2 1 Ribonuclease R winged-helix domain RNase_II_C_S1 PF18614.1 AAZ33054.1 - 1.2e-05 25.1 0.5 0.0016 18.4 0.1 2.9 3 0 0 3 3 3 1 RNase II-type exonuclease C-terminal S1 domain TRAM_2 PF18693.1 AAZ33054.1 - 0.01 16.0 0.6 0.15 12.3 0.1 3.0 3 0 0 3 3 3 0 TRAM domain TRAM PF01938.20 AAZ33054.1 - 0.033 14.2 0.8 0.19 11.8 0.4 2.3 2 0 0 2 2 2 0 TRAM domain OB_Dis3 PF17849.1 AAZ33054.1 - 0.065 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Dis3-like cold-shock domain 2 (CSD2) SRP-alpha_N PF04086.13 AAZ33054.1 - 0.99 9.3 8.2 1.6 8.6 8.2 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Sigma54_activat PF00158.26 AAZ33055.1 - 1.2e-54 184.6 0.0 2e-54 183.8 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AAZ33055.1 - 4.5e-17 62.4 0.0 1.2e-16 61.1 0.0 1.6 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 AAZ33055.1 - 1.3e-09 37.6 0.6 2.5e-09 36.8 0.6 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 AAZ33055.1 - 6e-09 36.0 0.0 1.4e-08 34.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA PF00004.29 AAZ33055.1 - 0.00053 20.4 0.0 0.00098 19.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 AAZ33055.1 - 0.0013 18.2 0.1 0.17 11.3 0.1 2.2 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI MCM PF00493.23 AAZ33055.1 - 0.0051 15.9 0.0 0.011 14.8 0.0 1.4 1 1 0 1 1 1 1 MCM P-loop domain AAA_2 PF07724.14 AAZ33055.1 - 0.013 15.6 0.0 0.044 13.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) Scramblase PF03803.15 AAZ33055.1 - 0.013 14.8 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Scramblase AAA_22 PF13401.6 AAZ33055.1 - 0.014 15.6 0.2 0.21 11.8 0.1 2.6 2 1 0 2 2 2 0 AAA domain RNase_T PF00929.24 AAZ33057.1 - 4.2e-33 115.2 0.0 4.7e-33 115.1 0.0 1.0 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 AAZ33057.1 - 8.3e-06 25.9 0.1 1.2e-05 25.4 0.1 1.3 1 1 0 1 1 1 1 3' exoribonuclease, RNase T-like MotA_ExbB PF01618.16 AAZ33058.1 - 5.1e-30 103.8 2.3 8.9e-30 103.0 0.2 2.0 2 0 0 2 2 2 1 MotA/TolQ/ExbB proton channel family HemY_N PF07219.13 AAZ33058.1 - 0.32 11.2 2.0 0.55 10.5 0.1 2.2 2 0 0 2 2 2 0 HemY protein N-terminus Rot1 PF10681.9 AAZ33059.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Chaperone for protein-folding within the ER, fungal DUF4130 PF13566.6 AAZ33060.1 - 2.2e-37 128.3 0.2 2.8e-37 128.0 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4130 BPD_transp_2 PF02653.16 AAZ33061.1 - 1.3e-48 165.5 31.9 1.3e-48 165.5 31.9 2.0 2 0 0 2 2 2 2 Branched-chain amino acid transport system / permease component DUF3382 PF11862.8 AAZ33061.1 - 2.1e-23 82.4 1.5 2.1e-23 82.4 1.5 4.4 5 0 0 5 5 5 1 Domain of unknown function (DUF3382) YqjK PF13997.6 AAZ33061.1 - 1.2 9.5 5.6 0.26 11.5 0.4 2.6 2 0 0 2 2 2 0 YqjK-like protein ABC_tran PF00005.27 AAZ33062.1 - 1.6e-31 109.6 0.0 3e-31 108.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter TOBE_2 PF08402.10 AAZ33062.1 - 5.1e-11 42.6 0.2 3.4e-10 39.9 0.1 2.3 2 0 0 2 2 2 1 TOBE domain AAA_21 PF13304.6 AAZ33062.1 - 3.2e-08 33.7 0.8 3.7e-05 23.7 0.1 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAZ33062.1 - 0.00059 19.3 0.0 0.0027 17.2 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 AAZ33062.1 - 0.0029 17.8 0.1 0.022 15.0 0.1 2.2 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 AAZ33062.1 - 0.0037 17.2 0.0 0.0059 16.5 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 AAZ33062.1 - 0.0043 17.3 0.2 0.015 15.6 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 AAZ33062.1 - 0.013 15.9 0.0 0.063 13.7 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 AAZ33062.1 - 0.063 13.5 0.4 0.14 12.4 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 AAZ33062.1 - 0.17 12.2 1.9 0.78 10.1 1.9 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 AAZ33062.1 - 0.21 12.0 0.0 0.32 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 AAZ33064.1 - 4.2e-67 225.1 0.0 6.1e-67 224.5 0.0 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain Response_reg PF00072.24 AAZ33064.1 - 4.2e-28 97.8 0.0 7.5e-28 96.9 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Sigma54_activ_2 PF14532.6 AAZ33064.1 - 2.5e-19 69.8 0.0 1.8e-18 67.0 0.0 2.4 2 1 0 2 2 2 1 Sigma-54 interaction domain HTH_8 PF02954.19 AAZ33064.1 - 1.6e-13 50.2 1.9 4.3e-13 48.8 1.9 1.8 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 AAZ33064.1 - 7.4e-06 26.0 0.0 1.7e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM PF00493.23 AAZ33064.1 - 5.3e-05 22.4 0.0 9.8e-05 21.5 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain AAA PF00004.29 AAZ33064.1 - 0.0001 22.7 0.0 0.00018 22.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FleQ PF06490.11 AAZ33064.1 - 0.00016 22.0 0.0 0.00083 19.7 0.0 2.2 2 0 0 2 2 2 1 Flagellar regulatory protein FleQ AAA_16 PF13191.6 AAZ33064.1 - 0.00017 22.1 0.8 0.00097 19.6 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain HTH_30 PF13556.6 AAZ33064.1 - 0.00037 20.2 0.0 0.00084 19.1 0.0 1.5 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_20 PF12840.7 AAZ33064.1 - 0.0015 18.6 0.2 0.005 16.9 0.2 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain MerR PF00376.23 AAZ33064.1 - 0.0016 18.1 0.0 0.0043 16.8 0.0 1.7 1 0 0 1 1 1 1 MerR family regulatory protein AAA_3 PF07726.11 AAZ33064.1 - 0.0018 18.1 0.0 0.0035 17.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) HTH_28 PF13518.6 AAZ33064.1 - 0.0027 17.8 0.1 0.0063 16.6 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AAZ33064.1 - 0.0037 17.0 0.2 0.01 15.6 0.2 1.7 1 0 0 1 1 1 1 Homeodomain-like domain AAA_2 PF07724.14 AAZ33064.1 - 0.015 15.4 0.0 0.027 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) HTH_24 PF13412.6 AAZ33064.1 - 0.03 13.9 0.9 0.15 11.7 0.0 2.6 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 AAZ33064.1 - 0.031 14.2 0.0 0.084 12.8 0.0 1.8 1 0 0 1 1 1 0 HTH domain HTH_1 PF00126.27 AAZ33064.1 - 0.047 13.6 0.5 0.28 11.2 0.1 2.6 2 0 0 2 2 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Sigma70_r4_2 PF08281.12 AAZ33064.1 - 0.053 13.2 0.1 0.18 11.5 0.1 1.9 1 0 0 1 1 1 0 Sigma-70, region 4 AAA_7 PF12775.7 AAZ33064.1 - 0.054 13.0 0.0 0.19 11.2 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region ATPase PF06745.13 AAZ33064.1 - 0.058 12.7 0.0 0.17 11.2 0.0 1.7 2 0 0 2 2 2 0 KaiC Mg_chelatase PF01078.21 AAZ33064.1 - 0.061 12.7 0.0 7.2 5.9 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI HTH_17 PF12728.7 AAZ33064.1 - 0.082 13.1 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain AAA_22 PF13401.6 AAZ33064.1 - 0.14 12.4 0.0 0.85 9.9 0.0 2.2 3 0 0 3 3 2 0 AAA domain HTH_Mga PF08280.11 AAZ33064.1 - 0.16 12.0 0.0 0.48 10.5 0.0 1.7 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain GDP_Man_Dehyd PF16363.5 AAZ33065.1 - 5.3e-102 341.6 0.0 6.4e-102 341.4 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 AAZ33065.1 - 1.2e-69 234.4 0.0 1.7e-69 233.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 AAZ33065.1 - 1e-13 51.1 0.0 2.4e-13 49.8 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 AAZ33065.1 - 8.3e-13 48.1 0.0 1.3e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 AAZ33065.1 - 2.7e-10 39.7 0.0 4.4e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 AAZ33065.1 - 1e-09 37.9 0.0 1.2e-07 31.2 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 AAZ33065.1 - 0.00079 18.9 0.0 0.42 10.0 0.0 2.8 2 1 0 2 2 2 2 short chain dehydrogenase NAD_binding_10 PF13460.6 AAZ33065.1 - 0.012 15.5 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding PAAR_motif PF05488.13 AAZ33066.1 - 5.4e-23 80.9 0.2 6.2e-23 80.7 0.2 1.1 1 0 0 1 1 1 1 PAAR motif Sigma54_activat PF00158.26 AAZ33067.1 - 1.5e-70 236.3 0.0 2.2e-70 235.7 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Response_reg PF00072.24 AAZ33067.1 - 2.3e-29 101.8 0.0 5.5e-29 100.6 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain Sigma54_activ_2 PF14532.6 AAZ33067.1 - 2.6e-24 85.9 0.0 2.2e-23 82.9 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 AAZ33067.1 - 1.3e-13 50.5 1.0 5.6e-13 48.4 0.2 2.5 3 0 0 3 3 3 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 AAZ33067.1 - 8.4e-08 32.3 0.0 1.8e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 AAZ33067.1 - 0.00057 20.3 0.0 0.0019 18.7 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 AAZ33067.1 - 0.00088 19.4 0.0 0.0014 18.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) HsbA PF12296.8 AAZ33067.1 - 0.0028 18.1 0.0 0.0065 16.9 0.0 1.6 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Mg_chelatase PF01078.21 AAZ33067.1 - 0.014 14.8 0.1 1.3 8.4 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI FleQ PF06490.11 AAZ33067.1 - 0.014 15.7 0.0 0.048 14.0 0.0 2.0 2 0 0 2 2 2 0 Flagellar regulatory protein FleQ MCM PF00493.23 AAZ33067.1 - 0.085 11.9 0.0 0.18 10.9 0.0 1.5 1 1 0 1 1 1 0 MCM P-loop domain OKR_DC_1_N PF03709.15 AAZ33067.1 - 0.13 12.6 0.0 0.36 11.1 0.0 1.7 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain AAA_7 PF12775.7 AAZ33067.1 - 0.17 11.4 0.0 0.38 10.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region LysR_substrate PF03466.20 AAZ33068.1 - 2.6e-26 92.3 2.0 3e-26 92.1 1.1 1.4 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ33068.1 - 1.7e-13 50.3 0.0 7.8e-13 48.2 0.0 2.2 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AAZ33068.1 - 0.0021 17.8 0.1 0.011 15.5 0.0 2.3 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain HTH_5 PF01022.20 AAZ33068.1 - 0.0076 16.1 0.1 0.016 15.1 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 AAZ33068.1 - 0.022 14.6 0.0 0.075 12.9 0.0 1.9 1 0 0 1 1 1 0 MarR family HTH_24 PF13412.6 AAZ33068.1 - 0.022 14.3 0.0 0.05 13.2 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.16 AAZ33068.1 - 0.032 13.7 0.0 0.068 12.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_27 PF13463.6 AAZ33068.1 - 0.04 14.4 0.1 0.13 12.8 0.0 1.9 1 1 1 2 2 2 0 Winged helix DNA-binding domain Fe_dep_repress PF01325.19 AAZ33068.1 - 0.078 13.2 0.1 0.47 10.7 0.0 2.1 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain HTH_Mga PF08280.11 AAZ33068.1 - 0.085 12.9 0.0 0.22 11.6 0.0 1.7 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain Condensation PF00668.20 AAZ33069.1 - 3.5e-113 378.7 0.0 4.6e-113 378.3 0.0 1.1 1 0 0 1 1 1 1 Condensation domain AMP-binding PF00501.28 AAZ33069.1 - 2.9e-104 349.0 0.0 4.2e-104 348.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 AAZ33069.1 - 5.5e-29 101.9 0.0 9.1e-29 101.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain TubC_N PF18563.1 AAZ33069.1 - 2.7e-12 46.5 0.1 7e-12 45.1 0.1 1.7 1 0 0 1 1 1 1 TubC N-terminal docking domain PP-binding PF00550.25 AAZ33069.1 - 1.6e-11 44.4 0.0 6.2e-11 42.5 0.0 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.7 AAZ33069.1 - 1.8e-08 35.3 0.9 1.8e-08 35.3 0.9 3.5 3 1 0 3 3 3 1 Alpha/beta hydrolase family AMP-binding_C PF13193.6 AAZ33069.1 - 2.6e-05 25.1 0.0 0.00011 23.2 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF2974 PF11187.8 AAZ33069.1 - 0.052 13.1 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) TPR_2 PF07719.17 AAZ33070.1 - 0.077 13.2 0.1 0.53 10.5 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat HlyU PF10115.9 AAZ33071.1 - 0.019 15.0 0.0 0.021 14.8 0.0 1.0 1 0 0 1 1 1 0 Transcriptional activator HlyU Autoind_bind PF03472.15 AAZ33072.1 - 2.5e-34 117.9 0.2 3.1e-34 117.6 0.2 1.1 1 0 0 1 1 1 1 Autoinducer binding domain GerE PF00196.19 AAZ33072.1 - 1.1e-16 60.1 0.4 1.7e-16 59.5 0.4 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AAZ33072.1 - 6.9e-06 25.6 0.1 2e-05 24.2 0.0 1.9 1 1 1 2 2 2 1 Sigma-70, region 4 HTH_28 PF13518.6 AAZ33072.1 - 0.00068 19.7 0.0 0.0015 18.6 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 AAZ33072.1 - 0.0015 18.0 0.0 0.0029 17.1 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 AAZ33072.1 - 0.0041 16.9 0.0 0.0098 15.7 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_10 PF04967.12 AAZ33072.1 - 0.02 14.7 0.2 0.11 12.3 0.0 2.2 2 0 0 2 2 2 0 HTH DNA binding domain HTH_20 PF12840.7 AAZ33072.1 - 0.02 14.9 0.0 0.04 14.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain MotY_N PF18393.1 AAZ33073.1 - 3.9e-42 143.8 0.0 5.8e-42 143.3 0.0 1.3 1 0 0 1 1 1 1 MotY N-terminal domain OmpA PF00691.20 AAZ33073.1 - 5.8e-17 61.9 0.0 8.5e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 OmpA family ABC-3 PF00950.17 AAZ33074.1 - 3.1e-51 174.4 31.8 3.5e-51 174.2 31.8 1.0 1 0 0 1 1 1 1 ABC 3 transport family P2_Phage_GpR PF06891.11 AAZ33075.1 - 8.8e-26 90.5 0.2 1.1e-25 90.3 0.2 1.1 1 0 0 1 1 1 1 P2 phage tail completion protein R (GpR) SMC_ScpB PF04079.16 AAZ33076.1 - 3.8e-49 166.4 0.0 4.9e-49 166.0 0.0 1.1 1 0 0 1 1 1 1 Segregation and condensation complex subunit ScpB PSD5 PF07637.11 AAZ33076.1 - 0.072 13.5 0.1 0.83 10.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1595) MucB_RseB PF03888.14 AAZ33077.1 - 4e-53 179.6 0.2 5.4e-53 179.2 0.2 1.1 1 0 0 1 1 1 1 MucB/RseB N-terminal domain MucB_RseB_C PF17188.4 AAZ33077.1 - 2.6e-25 88.5 0.1 4.7e-25 87.6 0.1 1.4 1 0 0 1 1 1 1 MucB/RseB C-terminal domain LolA_like PF17131.4 AAZ33077.1 - 0.00027 20.7 0.0 0.00048 19.9 0.0 1.4 1 0 0 1 1 1 1 Outer membrane lipoprotein-sorting protein PQQ PF01011.21 AAZ33079.1 - 3.2e-37 124.7 0.6 1.6e-05 24.6 0.0 8.1 8 0 0 8 8 8 7 PQQ enzyme repeat PQQ_2 PF13360.6 AAZ33079.1 - 1.8e-21 76.8 0.6 1.2e-07 31.5 0.0 4.4 2 1 0 3 3 3 3 PQQ-like domain PQQ_3 PF13570.6 AAZ33079.1 - 7.1e-06 26.3 30.3 0.83 10.2 0.0 9.1 9 1 0 9 9 9 4 PQQ-like domain DUF3040 PF11239.8 AAZ33079.1 - 3.9 7.8 7.9 1.6 9.0 3.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) NMT1 PF09084.11 AAZ33080.1 - 5.2e-14 52.7 0.0 8.1e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 AAZ33080.1 - 3.9e-10 39.9 0.6 5.6e-10 39.3 0.6 1.2 1 0 0 1 1 1 1 NMT1-like family SBP_bac_3 PF00497.20 AAZ33080.1 - 5.1e-09 35.9 0.1 1.8e-08 34.1 0.1 1.8 1 1 1 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.7 AAZ33080.1 - 6.9e-07 29.1 1.4 1.7e-06 27.9 1.4 1.7 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein OpuAC PF04069.12 AAZ33080.1 - 6.7e-06 25.9 1.5 8.8e-06 25.5 0.6 1.6 2 0 0 2 2 2 1 Substrate binding domain of ABC-type glycine betaine transport system NMT1_3 PF16868.5 AAZ33080.1 - 1.4e-05 24.7 0.0 2.7e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 NMT1-like family FtsK_gamma PF09397.10 AAZ33080.1 - 0.061 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Ftsk gamma domain CYSTM PF12734.7 AAZ33080.1 - 0.2 12.0 0.0 0.59 10.5 0.0 1.8 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance Fimbrial PF00419.20 AAZ33081.1 - 1.2e-05 25.7 0.1 8.7e-05 22.8 0.0 2.1 2 1 1 3 3 3 1 Fimbrial protein FimA PF16970.5 AAZ33081.1 - 0.026 14.7 1.4 2.8 8.1 1.4 2.4 1 1 0 1 1 1 0 Type-1 fimbrial protein, A Methyltransf_9 PF08003.11 AAZ33083.1 - 1.7e-149 497.0 0.0 1.9e-149 496.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.6 AAZ33083.1 - 9.7e-12 45.0 0.0 1.8e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAZ33083.1 - 2e-08 34.2 0.0 1e-07 31.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAZ33083.1 - 8.4e-08 32.8 0.0 1.1e-06 29.2 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAZ33083.1 - 9.1e-08 32.7 0.0 2e-06 28.3 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAZ33083.1 - 0.00029 21.5 0.0 0.00073 20.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 AAZ33083.1 - 0.16 11.5 0.1 0.4 10.2 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain CMAS PF02353.20 AAZ33083.1 - 0.46 9.7 1.3 0.59 9.4 0.3 1.8 2 1 0 2 2 2 0 Mycolic acid cyclopropane synthetase Abhydrolase_6 PF12697.7 AAZ33084.1 - 2.8e-10 41.2 0.0 3.3e-10 40.9 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AAZ33084.1 - 5.3e-07 29.6 0.1 2.6e-05 24.0 0.1 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AAZ33084.1 - 4.1e-06 26.2 0.0 6.8e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 AAZ33084.1 - 0.015 15.4 0.1 5.8 6.9 0.0 2.2 2 0 0 2 2 2 0 Thioesterase domain DUF2920 PF11144.8 AAZ33084.1 - 0.03 13.5 0.0 0.039 13.1 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2920) FSH1 PF03959.13 AAZ33084.1 - 0.12 12.1 0.0 0.55 9.9 0.0 2.0 1 1 0 1 1 1 0 Serine hydrolase (FSH1) FabA PF07977.13 AAZ33085.1 - 0.0019 17.8 0.0 0.0041 16.8 0.0 1.5 1 1 0 1 1 1 1 FabA-like domain CSTF_C PF14304.6 AAZ33085.1 - 0.094 12.3 0.5 0.16 11.6 0.5 1.3 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal Spermine_synth PF01564.17 AAZ33086.1 - 2.3e-62 209.8 0.0 4.4e-62 208.8 0.0 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 AAZ33086.1 - 2.3e-14 53.0 0.1 4.7e-14 52.0 0.1 1.5 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 AAZ33086.1 - 3.2e-06 27.7 0.0 6.5e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAZ33086.1 - 2e-05 25.1 0.0 6.5e-05 23.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AAZ33086.1 - 0.00014 21.4 0.0 0.00021 20.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 AAZ33086.1 - 0.0028 17.5 0.0 0.0042 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAZ33086.1 - 0.0036 18.0 0.0 0.0086 16.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_30 PF05430.11 AAZ33086.1 - 0.017 15.0 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_23 PF13489.6 AAZ33086.1 - 0.017 15.0 0.0 0.038 13.8 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Pyr_redox_2 PF07992.14 AAZ33086.1 - 0.11 11.7 0.1 0.21 10.8 0.1 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RrnaAD PF00398.20 AAZ33086.1 - 0.15 11.1 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Shikimate_DH PF01488.20 AAZ33086.1 - 0.28 11.3 0.8 0.76 9.8 0.4 1.8 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase EamA PF00892.20 AAZ33087.1 - 3.9e-26 91.8 39.1 5.9e-13 49.2 13.0 2.0 2 0 0 2 2 2 2 EamA-like transporter family DUF4234 PF14018.6 AAZ33087.1 - 0.4 10.8 4.0 0.22 11.7 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) Ribonuc_L-PSP PF01042.21 AAZ33089.1 - 4.8e-29 100.8 0.0 5.7e-29 100.6 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP HATPase_c PF02518.26 AAZ33090.1 - 1.9e-12 47.7 0.0 2.8e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAZ33090.1 - 1.4e-05 25.1 0.1 2.8e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 AAZ33090.1 - 0.00028 20.8 0.0 0.00049 20.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain Amidase_3 PF01520.18 AAZ33091.1 - 6.3e-45 153.4 0.1 9e-45 152.9 0.1 1.2 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase AMIN PF11741.8 AAZ33091.1 - 6.7e-24 83.9 0.1 1.3e-23 82.9 0.1 1.5 1 0 0 1 1 1 1 AMIN domain LysM PF01476.20 AAZ33091.1 - 9.1e-13 48.0 0.0 3.9e-12 46.0 0.0 2.2 2 0 0 2 2 2 1 LysM domain HlyIII PF03006.20 AAZ33092.1 - 1.4e-40 139.4 23.3 1.9e-40 139.0 23.3 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF747 PF05346.11 AAZ33092.1 - 1 8.8 4.4 5.8 6.3 0.4 2.2 1 1 1 2 2 2 0 Eukaryotic membrane protein family Peptidase_S8 PF00082.22 AAZ33093.1 - 4.4e-18 65.6 0.0 6.9e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 Subtilase family PrpF PF04303.13 AAZ33094.1 - 9.9e-174 577.6 2.5 1.1e-173 577.4 2.5 1.0 1 0 0 1 1 1 1 PrpF protein DUF3757 PF12582.8 AAZ33095.1 - 2.8e-23 82.6 0.1 3.3e-23 82.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3757) AbiEi_3_N PF17194.4 AAZ33095.1 - 0.15 12.1 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin N-terminal domain HAD_2 PF13419.6 AAZ33096.1 - 2.3e-05 24.5 0.0 2.8e-05 24.3 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AAZ33096.1 - 0.00051 20.0 0.0 0.00063 19.8 0.0 1.1 1 0 0 1 1 1 1 HAD-hyrolase-like HATPase_c PF02518.26 AAZ33097.1 - 3.4e-22 79.1 0.0 6.5e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAZ33097.1 - 2.2e-12 46.8 0.3 7.3e-12 45.1 0.1 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AAZ33097.1 - 1.1e-11 44.9 2.5 4e-11 43.1 1.3 2.6 2 0 0 2 2 2 1 HAMP domain HATPase_c_3 PF13589.6 AAZ33097.1 - 5.3e-05 23.1 0.0 9.4e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AAZ33097.1 - 0.0001 22.2 0.1 0.00066 19.6 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain DUF4381 PF14316.6 AAZ33097.1 - 0.36 11.1 2.5 0.56 10.4 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) FixQ PF05545.11 AAZ33097.1 - 0.87 9.6 2.9 29 4.7 0.1 2.4 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Cytochrom_C PF00034.21 AAZ33098.1 - 2.9e-09 37.9 0.0 3.8e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 AAZ33098.1 - 2.3e-05 24.6 0.2 7e-05 23.1 0.2 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Fer4 PF00037.27 AAZ33099.1 - 2.2e-14 52.6 16.6 7.1e-09 35.1 0.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 AAZ33099.1 - 9.1e-12 45.4 10.4 1.5e-11 44.7 10.4 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 AAZ33099.1 - 4.4e-10 39.5 8.8 5.4e-05 23.2 4.1 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAZ33099.1 - 6.4e-10 39.8 6.6 0.00013 22.8 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 AAZ33099.1 - 3.6e-09 36.6 19.2 3.1e-06 27.2 12.0 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 AAZ33099.1 - 1.4e-08 35.1 1.6 0.0017 18.7 0.0 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAZ33099.1 - 1.2e-07 31.8 10.4 4.9e-07 29.8 10.9 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAZ33099.1 - 5.2e-07 30.1 3.7 0.0066 17.0 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAZ33099.1 - 5.9e-06 26.1 12.7 0.013 15.6 1.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 AAZ33099.1 - 3e-05 23.9 16.9 0.0047 16.9 0.9 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_22 PF17179.4 AAZ33099.1 - 0.00046 21.0 4.0 0.52 11.2 0.5 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 AAZ33099.1 - 0.00059 20.3 6.9 0.19 12.3 0.3 2.7 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_4 PF12800.7 AAZ33099.1 - 0.0011 19.3 13.4 0.07 13.7 1.2 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.6 AAZ33099.1 - 0.0044 17.2 4.5 0.48 10.6 1.0 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 AAZ33099.1 - 0.0089 16.9 3.6 0.0089 16.9 3.6 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain ETF_QO PF05187.13 AAZ33099.1 - 0.19 11.9 5.6 0.43 10.7 2.6 2.1 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_15 PF13459.6 AAZ33099.1 - 2.9 8.7 13.2 0.82 10.5 0.3 2.8 2 1 0 2 2 2 0 4Fe-4S single cluster domain CstA PF02554.14 AAZ33100.1 - 7.5e-167 555.0 28.5 7.5e-167 555.0 28.5 1.7 2 0 0 2 2 2 1 Carbon starvation protein CstA CstA_5TM PF13722.6 AAZ33100.1 - 2.4e-35 121.4 6.8 2.4e-35 121.4 6.8 3.8 4 0 0 4 4 4 1 5TM C-terminal transporter carbon starvation CstA DUF1820 PF08850.11 AAZ33101.1 - 4.1e-43 145.8 0.4 4.8e-43 145.6 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1820) DUF485 PF04341.12 AAZ33102.1 - 4.5e-34 116.3 0.1 5.1e-34 116.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF485 E1-E2_ATPase PF00122.20 AAZ33102.1 - 0.17 11.4 0.4 0.2 11.2 0.4 1.1 1 0 0 1 1 1 0 E1-E2 ATPase CbtB PF09489.10 AAZ33102.1 - 0.2 11.8 0.6 0.46 10.6 0.1 1.8 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) FixS PF03597.15 AAZ33102.1 - 0.24 11.2 0.0 0.24 11.2 0.0 2.2 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type DUF202 PF02656.15 AAZ33102.1 - 0.47 10.9 3.1 0.65 10.5 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF202) ATP-synt_ab PF00006.25 AAZ33103.1 - 2.1e-63 213.9 0.0 2.8e-63 213.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 AAZ33103.1 - 2.5e-22 79.1 1.3 6.3e-22 77.9 1.3 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain T3SS_ATPase_C PF18269.1 AAZ33103.1 - 0.12 12.2 0.6 0.64 9.9 0.6 2.1 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain Acetyltransf_3 PF13302.7 AAZ33104.1 - 2.9e-11 44.2 0.1 4e-11 43.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAZ33104.1 - 0.0013 19.0 0.0 0.002 18.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 AAZ33104.1 - 0.0095 16.1 0.0 0.014 15.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4880 PF16220.5 AAZ33104.1 - 0.37 10.7 6.4 2.3 8.2 0.4 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4880) Pyr_redox_2 PF07992.14 AAZ33105.1 - 1.1e-47 162.7 3.6 1.8e-47 162.0 3.6 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAZ33105.1 - 4.7e-22 78.6 1.3 5.7e-19 68.5 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAZ33105.1 - 5.3e-14 52.5 7.6 1.1e-12 48.3 0.4 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AAZ33105.1 - 1.5e-10 40.8 10.2 0.00013 21.2 1.2 3.9 4 1 1 5 5 5 3 Glucose inhibited division protein A Thioredoxin_3 PF13192.6 AAZ33105.1 - 3.1e-09 36.8 0.0 1.2e-08 34.8 0.0 2.1 2 0 0 2 2 1 1 Thioredoxin domain FAD_binding_2 PF00890.24 AAZ33105.1 - 4.8e-07 29.2 20.7 0.0086 15.2 0.2 4.5 2 2 3 5 5 5 2 FAD binding domain DAO PF01266.24 AAZ33105.1 - 5.4e-05 22.9 11.1 0.049 13.2 3.0 3.4 3 0 0 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.14 AAZ33105.1 - 7e-05 21.7 8.4 0.17 10.6 1.4 3.3 3 0 0 3 3 3 2 HI0933-like protein FAD_oxidored PF12831.7 AAZ33105.1 - 0.00011 21.7 5.6 0.00011 21.7 5.6 3.4 2 2 1 3 3 3 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 AAZ33105.1 - 0.00039 19.8 3.1 0.24 10.7 0.1 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 AAZ33105.1 - 0.00065 19.0 0.5 0.033 13.4 0.1 2.4 2 0 0 2 2 2 1 Thi4 family Glutaredoxin PF00462.24 AAZ33105.1 - 0.0018 18.5 0.1 0.021 15.0 0.0 2.9 3 0 0 3 3 2 1 Glutaredoxin K_oxygenase PF13434.6 AAZ33105.1 - 0.0072 15.5 2.3 0.014 14.6 0.1 2.3 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 AAZ33105.1 - 0.0073 15.6 0.8 0.0073 15.6 0.8 2.5 2 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 AAZ33105.1 - 0.0084 16.3 4.2 0.032 14.5 0.5 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 AAZ33105.1 - 0.013 15.9 0.6 4.6 7.7 0.0 2.7 2 0 0 2 2 2 0 Putative NAD(P)-binding FMO-like PF00743.19 AAZ33105.1 - 0.04 12.4 0.0 0.077 11.4 0.0 1.4 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like Trp_halogenase PF04820.14 AAZ33105.1 - 0.42 9.4 6.3 2.2 7.0 1.4 2.6 3 0 0 3 3 3 0 Tryptophan halogenase ThiF PF00899.21 AAZ33105.1 - 0.78 9.0 2.6 11 5.3 0.3 2.3 2 0 0 2 2 2 0 ThiF family NAD_binding_9 PF13454.6 AAZ33105.1 - 1.6 8.7 6.5 5.2 7.0 0.0 3.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding LysR_substrate PF03466.20 AAZ33107.1 - 9.7e-25 87.2 0.2 2.5e-24 85.8 0.2 1.8 1 0 0 1 1 1 1 LysR substrate binding domain rve PF00665.26 AAZ33107.1 - 1.1e-13 51.4 0.0 4e-13 49.6 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain HTH_1 PF00126.27 AAZ33107.1 - 2.9e-13 49.6 0.1 9.4e-13 47.9 0.1 2.0 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_11 PF08279.12 AAZ33107.1 - 8.1e-05 22.5 0.3 0.46 10.5 0.1 3.4 3 0 0 3 3 3 1 HTH domain HTH_23 PF13384.6 AAZ33107.1 - 0.00013 21.7 0.1 0.00043 20.0 0.1 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_30 PF13556.6 AAZ33107.1 - 0.00016 21.4 0.3 0.32 10.8 0.0 2.6 2 0 0 2 2 2 2 PucR C-terminal helix-turn-helix domain DUF1804 PF08822.11 AAZ33107.1 - 0.00068 19.6 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1804) HTH_28 PF13518.6 AAZ33107.1 - 0.00068 19.7 0.2 0.34 11.1 0.1 2.9 3 0 0 3 3 2 1 Helix-turn-helix domain HTH_36 PF13730.6 AAZ33107.1 - 0.00071 19.5 0.7 0.039 13.9 0.1 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 AAZ33107.1 - 0.00083 19.3 0.2 0.05 13.6 0.0 2.6 2 0 0 2 2 2 1 Winged helix-turn helix HTH_3 PF01381.22 AAZ33107.1 - 0.0013 18.7 0.0 0.005 16.9 0.0 2.0 1 0 0 1 1 1 1 Helix-turn-helix HTH_IclR PF09339.10 AAZ33107.1 - 0.002 17.9 0.8 1.1 9.1 0.0 3.4 3 0 0 3 3 3 1 IclR helix-turn-helix domain Sigma70_r4 PF04545.16 AAZ33107.1 - 0.005 16.3 0.1 0.016 14.7 0.1 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_AsnC-type PF13404.6 AAZ33107.1 - 0.017 14.9 2.5 1.3 8.9 0.0 2.7 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_17 PF12728.7 AAZ33107.1 - 0.031 14.5 0.1 0.16 12.1 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_24 PF13412.6 AAZ33107.1 - 0.031 13.8 0.5 2 8.1 0.0 3.0 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding DUF746 PF05344.11 AAZ33107.1 - 0.033 14.0 0.0 0.21 11.4 0.0 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF746) HTH_7 PF02796.15 AAZ33107.1 - 0.037 14.1 0.2 0.63 10.2 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_38 PF13936.6 AAZ33107.1 - 0.038 13.8 5.2 0.15 11.8 0.2 2.8 3 0 0 3 3 2 0 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 AAZ33107.1 - 0.053 13.9 0.4 0.24 11.7 0.0 2.2 2 0 0 2 2 2 0 Transposase HTH_40 PF14493.6 AAZ33107.1 - 0.054 13.9 0.0 0.15 12.5 0.0 1.8 1 1 0 1 1 1 0 Helix-turn-helix domain MarR_2 PF12802.7 AAZ33107.1 - 0.12 12.3 0.7 10 6.1 0.2 2.8 3 0 0 3 3 2 0 MarR family Sigma70_r4_2 PF08281.12 AAZ33107.1 - 0.14 11.8 0.1 0.65 9.7 0.0 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.6 AAZ33107.1 - 0.33 10.4 2.3 16 5.0 0.4 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 ApbE PF02424.15 AAZ33108.1 - 7.4e-65 219.0 0.0 8.5e-65 218.8 0.0 1.0 1 0 0 1 1 1 1 ApbE family Abhydrolase_1 PF00561.20 AAZ33109.1 - 7e-08 32.4 0.1 3.4e-06 26.9 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AAZ33109.1 - 1.1e-06 28.1 0.0 0.009 15.3 0.0 2.5 2 1 0 2 2 2 2 Serine aminopeptidase, S33 BAAT_C PF08840.11 AAZ33109.1 - 0.0056 16.6 0.0 0.011 15.7 0.0 1.4 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_4 PF08386.10 AAZ33109.1 - 0.043 13.9 0.0 0.16 12.1 0.0 1.9 2 0 0 2 2 2 0 TAP-like protein RFX_DNA_binding PF02257.15 AAZ33109.1 - 0.049 14.2 0.3 16 6.2 0.0 3.0 3 0 0 3 3 3 0 RFX DNA-binding domain Glyco_tran_WecB PF03808.13 AAZ33109.1 - 0.099 12.6 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Peptidase_S15 PF02129.18 AAZ33109.1 - 0.15 11.6 0.1 0.77 9.3 0.1 2.2 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) TAL_FSA PF00923.19 AAZ33110.1 - 2.1e-97 326.0 0.0 2.3e-97 325.8 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase HTH_8 PF02954.19 AAZ33111.1 - 6e-14 51.6 0.1 8.9e-14 51.0 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family Phage_NinH PF06322.11 AAZ33111.1 - 0.026 14.4 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 Phage NinH protein HTH_28 PF13518.6 AAZ33111.1 - 0.15 12.2 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain UPF0175 PF03683.13 AAZ33111.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) FA_desaturase PF00487.24 AAZ33112.1 - 3.9e-12 46.6 13.4 1.2e-11 44.9 13.4 1.8 1 1 0 1 1 1 1 Fatty acid desaturase DDE_Tnp_ISL3 PF01610.17 AAZ33112.1 - 2.6e-09 37.1 2.0 6.1e-09 35.9 2.0 1.6 1 0 0 1 1 1 1 Transposase NapE PF06796.11 AAZ33112.1 - 0.11 12.1 3.9 0.29 10.7 3.9 1.8 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE ABC_tran PF00005.27 AAZ33113.1 - 2.2e-26 93.0 0.0 5e-26 91.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 AAZ33113.1 - 3.1e-12 46.7 8.2 4.6e-12 46.2 8.2 1.3 1 1 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.6 AAZ33113.1 - 1.4e-08 34.9 0.1 0.001 19.0 0.1 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAZ33113.1 - 5.1e-06 26.1 0.2 0.027 13.9 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AAZ33113.1 - 0.00024 21.5 0.0 0.00055 20.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AAZ33113.1 - 0.00032 21.0 0.0 0.0011 19.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain MobB PF03205.14 AAZ33113.1 - 0.00063 19.6 0.6 0.26 11.2 0.1 3.2 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.6 AAZ33113.1 - 0.0014 19.2 0.0 0.0029 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAZ33113.1 - 0.0017 18.1 0.0 0.0034 17.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 AAZ33113.1 - 0.0017 18.1 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 AAZ33113.1 - 0.0029 17.6 0.0 0.0072 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 AAZ33113.1 - 0.01 15.9 0.1 0.053 13.6 0.0 2.2 2 1 1 3 3 3 0 AAA domain NACHT PF05729.12 AAZ33113.1 - 0.011 15.7 0.5 0.068 13.1 0.0 2.5 3 0 0 3 3 3 0 NACHT domain ABC_ATPase PF09818.9 AAZ33113.1 - 0.013 14.3 0.4 0.9 8.3 0.1 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 AAZ33113.1 - 0.017 15.1 0.0 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase Zeta_toxin PF06414.12 AAZ33113.1 - 0.019 14.3 0.0 0.035 13.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ATPase_2 PF01637.18 AAZ33113.1 - 0.024 14.6 0.1 0.08 12.9 0.1 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Rad17 PF03215.15 AAZ33113.1 - 0.029 14.3 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA PF00004.29 AAZ33113.1 - 0.042 14.3 0.0 0.19 12.1 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 AAZ33113.1 - 0.052 13.0 0.2 0.46 9.9 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_7 PF12775.7 AAZ33113.1 - 0.083 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 AAZ33113.1 - 0.094 11.9 0.7 0.17 11.0 0.1 1.6 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.22 AAZ33113.1 - 0.098 13.1 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DLIC PF05783.11 AAZ33113.1 - 0.2 10.4 0.0 0.31 9.8 0.0 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) CobD_Cbib PF03186.13 AAZ33113.1 - 0.23 10.7 4.9 0.063 12.5 1.4 1.7 1 1 1 2 2 2 0 CobD/Cbib protein DUF4407 PF14362.6 AAZ33114.1 - 0.00041 19.8 1.3 0.00067 19.1 1.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) YlqD PF11068.8 AAZ33114.1 - 0.01 16.2 0.3 0.01 16.2 0.3 2.3 2 1 0 2 2 2 0 YlqD protein Prefoldin PF02996.17 AAZ33114.1 - 0.011 15.7 7.6 0.027 14.4 1.1 2.9 3 0 0 3 3 2 0 Prefoldin subunit PIN_8 PF18476.1 AAZ33114.1 - 0.019 14.8 0.5 0.019 14.8 0.5 1.8 2 0 0 2 2 2 0 PIN like domain DUF1192 PF06698.11 AAZ33114.1 - 0.021 14.8 0.2 0.08 13.0 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DivIC PF04977.15 AAZ33114.1 - 0.021 14.6 4.2 0.12 12.2 0.6 3.1 3 0 0 3 3 3 0 Septum formation initiator Spore_III_AB PF09548.10 AAZ33114.1 - 0.12 12.4 0.2 0.12 12.4 0.2 2.3 2 1 1 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) Fzo_mitofusin PF04799.13 AAZ33114.1 - 0.57 9.7 5.7 0.17 11.4 1.4 2.2 2 1 1 3 3 3 0 fzo-like conserved region Phage_GPO PF05929.11 AAZ33114.1 - 0.65 9.6 5.6 0.098 12.3 0.7 1.9 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase TolA_bind_tri PF16331.5 AAZ33114.1 - 1.6 8.9 7.2 0.15 12.2 0.6 2.7 3 0 0 3 3 3 0 TolA binding protein trimerisation DUF948 PF06103.11 AAZ33114.1 - 1.6 9.1 6.2 9 6.6 0.8 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) bZIP_1 PF00170.21 AAZ33114.1 - 2.1 8.5 9.1 2.5 8.3 1.6 2.7 2 0 0 2 2 2 0 bZIP transcription factor APG6_N PF17675.1 AAZ33114.1 - 3.7 8.1 10.0 0.11 13.1 0.8 2.8 3 0 0 3 3 3 0 Apg6 coiled-coil region Seryl_tRNA_N PF02403.22 AAZ33114.1 - 4.5 7.5 11.1 5.2 7.3 2.7 2.7 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain OmpH PF03938.14 AAZ33114.1 - 6.2 7.1 12.3 0.42 10.9 5.5 2.5 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) RHS_repeat PF05593.14 AAZ33115.1 - 6.6e-12 45.7 22.9 0.066 13.7 2.4 8.4 6 2 1 7 7 7 6 RHS Repeat ABC_tran PF00005.27 AAZ33116.1 - 1.5e-31 109.7 0.0 1.9e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 ABC transporter BCA_ABC_TP_C PF12399.8 AAZ33116.1 - 2.8e-11 43.1 0.2 5.7e-11 42.1 0.2 1.6 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_21 PF13304.6 AAZ33116.1 - 9.6e-07 28.9 1.5 0.00023 21.1 0.1 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 AAZ33116.1 - 2.7e-05 24.2 0.1 5.1e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 AAZ33116.1 - 0.00018 21.3 0.5 0.00097 18.9 0.5 1.9 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 AAZ33116.1 - 0.0015 18.1 0.7 0.6 9.6 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 AAZ33116.1 - 0.0018 18.7 0.1 0.0028 18.1 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AAZ33116.1 - 0.0018 18.0 0.1 0.0036 17.0 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AAZ33116.1 - 0.0025 18.3 0.1 0.004 17.7 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 AAZ33116.1 - 0.0027 17.5 0.0 0.0039 16.9 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 AAZ33116.1 - 0.0058 16.1 0.4 0.012 15.1 0.2 1.5 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 AAZ33116.1 - 0.0067 16.5 0.0 0.02 15.0 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_19 PF13245.6 AAZ33116.1 - 0.021 15.1 0.0 0.027 14.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 AAZ33116.1 - 0.026 13.4 0.2 1.7 7.4 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class TniB PF05621.11 AAZ33116.1 - 0.026 14.0 0.2 0.15 11.5 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein AAA_27 PF13514.6 AAZ33116.1 - 0.026 14.1 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AAZ33116.1 - 0.072 13.4 0.5 0.75 10.1 0.5 2.2 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 AAZ33116.1 - 0.072 12.6 0.0 0.92 9.0 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B IstB_IS21 PF01695.17 AAZ33116.1 - 0.074 12.8 0.1 0.25 11.1 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_10 PF12846.7 AAZ33116.1 - 0.12 11.3 0.1 0.29 10.0 0.0 1.7 2 1 0 2 2 2 0 AAA-like domain SPOR PF05036.13 AAZ33117.1 - 4.5e-18 65.4 2.0 5.2e-18 65.2 0.1 2.0 3 0 0 3 3 3 1 Sporulation related domain C166 PF17615.2 AAZ33117.1 - 0.1 12.7 0.6 0.18 11.9 0.6 1.4 1 0 0 1 1 1 0 Family of unknown function PHO4 PF01384.20 AAZ33118.1 - 9.8e-87 291.1 12.3 9.8e-87 291.1 12.3 1.9 2 1 0 2 2 2 1 Phosphate transporter family PsiF_repeat PF07769.14 AAZ33119.1 - 9.5e-38 127.8 20.2 8.2e-20 70.4 5.9 2.1 2 0 0 2 2 2 2 psiF repeat DUF2957 PF11170.8 AAZ33119.1 - 0.32 9.8 4.1 0.88 8.3 4.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2957) CcmH PF03918.14 AAZ33120.1 - 4.4e-56 188.1 0.0 5.4e-56 187.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C biogenesis protein DUF3565 PF12088.8 AAZ33120.1 - 0.087 12.8 0.4 3.4 7.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3565) DUF3797 PF12677.7 AAZ33120.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) HTH_38 PF13936.6 AAZ33120.1 - 0.16 11.8 1.1 6.5 6.6 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain CcmF_C PF16327.5 AAZ33120.1 - 0.19 11.0 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c-type biogenesis protein CcmF C-terminal Transposase_mut PF00872.18 AAZ33121.1 - 4e-116 388.0 0.0 5e-116 387.7 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ33121.1 - 7.7e-05 23.0 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain TonB_dep_Rec PF00593.24 AAZ33122.1 - 1.5e-36 127.3 29.2 2.4e-36 126.6 27.8 1.8 1 1 1 2 2 2 2 TonB dependent receptor Plug PF07715.15 AAZ33122.1 - 3.2e-12 47.0 0.2 8e-12 45.7 0.2 1.7 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain OMP_b-brl PF13505.6 AAZ33122.1 - 0.1 12.7 15.0 0.039 14.1 2.7 3.4 2 2 2 4 4 4 0 Outer membrane protein beta-barrel domain T6SS-SciN PF12790.7 AAZ33123.1 - 2.4e-28 98.3 0.0 3.9e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 LPAM_2 PF13627.6 AAZ33123.1 - 1.1 9.2 3.9 1.9 8.5 3.9 1.3 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site SBP_bac_3 PF00497.20 AAZ33124.1 - 1.4e-18 67.2 0.0 1.6e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lyase_aromatic PF00221.19 AAZ33125.1 - 2.6e-161 537.4 9.5 2.9e-161 537.2 9.5 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase CDPS PF16715.5 AAZ33125.1 - 0.081 12.6 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Cyclodipeptide synthase HisG PF01634.18 AAZ33126.1 - 7.5e-47 159.3 0.1 9.2e-47 159.0 0.1 1.1 1 0 0 1 1 1 1 ATP phosphoribosyltransferase NMT1 PF09084.11 AAZ33126.1 - 0.034 14.1 0.7 11 5.9 0.0 3.0 2 1 1 3 3 3 0 NMT1/THI5 like Bacteriocin_IId PF09221.10 AAZ33126.1 - 0.059 13.6 0.7 2.5 8.4 0.1 2.6 2 0 0 2 2 2 0 Bacteriocin class IId cyclical uberolysin-like Lactamase_B_2 PF12706.7 AAZ33127.1 - 2.4e-21 76.2 0.1 3.3e-21 75.7 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 AAZ33127.1 - 2.9e-16 60.1 0.1 4.5e-16 59.5 0.1 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 AAZ33127.1 - 0.00029 20.8 0.0 0.00045 20.1 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 AAZ33127.1 - 0.0036 16.8 0.0 0.0054 16.2 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain PDEase_II PF02112.15 AAZ33127.1 - 0.13 11.3 0.0 0.25 10.4 0.0 1.4 2 0 0 2 2 2 0 cAMP phosphodiesterases class-II Topoisom_I PF01028.20 AAZ33128.1 - 6.3e-34 117.2 0.0 1.6e-33 115.9 0.0 1.5 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Fer2_3 PF13085.6 AAZ33129.1 - 1e-29 102.8 0.0 1.5e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 AAZ33129.1 - 5.4e-09 36.5 2.2 1e-08 35.6 2.2 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 AAZ33129.1 - 1.2e-08 35.3 14.9 2.1e-07 31.3 4.0 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAZ33129.1 - 3.4e-07 30.3 1.7 6.5e-07 29.4 1.7 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAZ33129.1 - 0.00085 19.4 2.8 0.00085 19.4 2.8 2.1 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AAZ33129.1 - 0.0012 19.3 8.2 0.013 16.1 8.8 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_18 PF13746.6 AAZ33129.1 - 0.0041 17.3 2.5 0.97 9.6 0.1 2.9 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAZ33129.1 - 0.0067 17.3 2.2 3.6 8.6 1.0 2.4 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 AAZ33129.1 - 0.11 12.6 5.7 2.1 8.5 1.5 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 AAZ33129.1 - 0.14 12.8 7.8 4 8.2 1.9 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4 PF00037.27 AAZ33129.1 - 0.25 11.2 14.5 0.21 11.5 0.7 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.7 AAZ33129.1 - 2.2 8.5 12.0 0.23 11.6 0.8 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Mal_decarbox_Al PF16957.5 AAZ33131.1 - 5.4e-295 978.9 0.0 6.1e-295 978.7 0.0 1.0 1 0 0 1 1 1 1 Malonate decarboxylase, alpha subunit, transporter SnoaL_2 PF12680.7 AAZ33131.1 - 0.056 14.1 0.3 2.2 9.0 0.0 3.1 2 1 1 3 3 3 0 SnoaL-like domain MFS_1 PF07690.16 AAZ33132.1 - 1.1e-41 143.0 50.2 1.1e-41 143.0 50.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 AAZ33132.1 - 5.6e-08 31.8 9.6 5.6e-08 31.8 9.6 3.0 2 1 1 3 3 3 3 MFS/sugar transport protein DUF4096 PF13340.6 AAZ33133.1 - 5.7e-25 87.3 0.4 1.5e-24 86.0 0.4 1.8 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1 PF01609.21 AAZ33133.1 - 1.3e-13 51.1 0.0 2.3e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AAZ33133.1 - 7e-10 39.2 0.2 2.1e-09 37.6 0.2 1.9 1 0 0 1 1 1 1 Transposase DDE domain HTH_Tnp_Tc3_2 PF01498.18 AAZ33133.1 - 0.061 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Transposase Secretin PF00263.21 AAZ33134.1 - 4.7e-49 166.3 1.8 1e-48 165.2 1.8 1.6 1 0 0 1 1 1 1 Bacterial type II and III secretion system protein Secretin_N PF03958.17 AAZ33134.1 - 7.8e-13 48.6 3.4 2.1e-12 47.3 1.5 2.7 2 0 0 2 2 2 1 Bacterial type II/III secretion system short domain AMIN PF11741.8 AAZ33134.1 - 9.2e-10 38.5 3.4 1.2e-06 28.6 0.0 3.8 3 0 0 3 3 3 2 AMIN domain STN PF07660.14 AAZ33134.1 - 7.9e-08 32.0 1.2 4.1e-07 29.7 0.1 2.9 3 1 1 4 4 4 1 Secretin and TonB N terminus short domain TonB_C PF03544.14 AAZ33135.1 - 7.4e-15 55.2 0.0 2.4e-14 53.5 0.0 1.9 1 0 0 1 1 1 1 Gram-negative bacterial TonB protein C-terminal Rrn6 PF10214.9 AAZ33135.1 - 0.0059 15.2 11.8 0.0068 15.0 11.8 1.1 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor DDHD PF02862.17 AAZ33135.1 - 0.039 14.1 4.4 0.047 13.8 4.4 1.2 1 0 0 1 1 1 0 DDHD domain MID_MedPIWI PF18296.1 AAZ33135.1 - 0.076 12.8 8.4 0.1 12.4 8.4 1.1 1 0 0 1 1 1 0 MID domain of medPIWI ARGLU PF15346.6 AAZ33135.1 - 0.26 11.2 32.2 0.36 10.7 32.2 1.1 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 FAM60A PF15396.6 AAZ33135.1 - 0.27 11.2 7.9 0.37 10.8 7.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A TFIIA PF03153.13 AAZ33135.1 - 0.45 10.5 26.7 0.53 10.2 26.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hamartin PF04388.12 AAZ33135.1 - 0.46 9.1 11.6 0.57 8.8 11.6 1.0 1 0 0 1 1 1 0 Hamartin protein Presenilin PF01080.17 AAZ33135.1 - 0.62 8.8 16.9 0.77 8.5 16.9 1.1 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 AAZ33135.1 - 1.1 7.9 13.9 1.3 7.6 13.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF778 PF05608.12 AAZ33135.1 - 1.1 9.5 5.1 1.5 9.1 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF778) DUF390 PF04094.14 AAZ33135.1 - 1.8 6.8 16.7 2.1 6.5 16.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) Asp-B-Hydro_N PF05279.11 AAZ33135.1 - 1.8 8.5 15.5 2.4 8.2 15.5 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PAT1 PF09770.9 AAZ33135.1 - 3.3 5.8 22.7 3.9 5.6 22.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 V_ATPase_I PF01496.19 AAZ33135.1 - 3.5 5.4 10.9 4.1 5.2 10.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family eIF-3_zeta PF05091.12 AAZ33135.1 - 6.3 5.7 16.3 7.7 5.4 16.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Neur_chan_memb PF02932.16 AAZ33135.1 - 6.6 6.7 10.2 8.8 6.3 10.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region GREB1 PF15782.5 AAZ33135.1 - 9.4 3.2 12.9 11 3.0 12.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Glyco_transf_36 PF06165.11 AAZ33136.1 - 0.15 11.5 0.0 1.7 8.0 0.0 1.9 1 1 1 2 2 2 0 Glycosyltransferase family 36 DUF2442 PF10387.9 AAZ33137.1 - 4.7e-10 39.6 0.1 8.1e-10 38.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2442) HTH_31 PF13560.6 AAZ33137.1 - 0.00014 22.2 1.2 0.00026 21.3 1.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AAZ33137.1 - 0.0051 16.6 0.1 0.012 15.3 0.1 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_3 PF01381.22 AAZ33137.1 - 0.0066 16.5 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_29 PF13551.6 AAZ33137.1 - 0.014 15.4 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix HTH_8 PF02954.19 AAZ33137.1 - 0.1 12.4 0.1 0.28 11.0 0.1 1.8 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family Sel1 PF08238.12 AAZ33138.1 - 0.0017 18.9 0.3 0.006 17.2 0.3 2.0 1 0 0 1 1 1 1 Sel1 repeat cNMP_binding PF00027.29 AAZ33139.1 - 2e-19 69.4 0.0 3.4e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HTH_Crp_2 PF13545.6 AAZ33139.1 - 9.7e-12 44.7 0.0 1.9e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Crp PF00325.20 AAZ33139.1 - 1.1e-10 40.9 0.1 2.7e-10 39.7 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, crp family HTH_23 PF13384.6 AAZ33139.1 - 0.0021 17.8 0.0 0.0067 16.2 0.0 1.8 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 AAZ33139.1 - 0.008 16.1 0.0 0.021 14.7 0.0 1.7 1 0 0 1 1 1 1 MarR family MarR PF01047.22 AAZ33139.1 - 0.0086 16.0 0.1 0.022 14.7 0.1 1.7 1 0 0 1 1 1 1 MarR family TrmB PF01978.19 AAZ33139.1 - 0.05 13.5 0.1 0.094 12.6 0.1 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.12 AAZ33139.1 - 0.059 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 HTH domain HTH_28 PF13518.6 AAZ33139.1 - 0.067 13.3 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain ALS_ss_C PF10369.9 AAZ33140.1 - 9.3e-27 93.0 2.3 6.1e-26 90.4 0.8 2.1 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT_5 PF13710.6 AAZ33140.1 - 2.1e-15 56.3 0.0 4.1e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT PF01842.25 AAZ33140.1 - 5.6e-15 54.8 0.0 1.1e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 AAZ33140.1 - 0.0054 17.3 0.1 0.012 16.2 0.1 1.6 1 0 0 1 1 1 1 ACT domain T2SSF PF00482.23 AAZ33141.1 - 3.1e-17 62.7 0.3 7.4e-17 61.5 0.3 1.7 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein F SbcD_C PF12320.8 AAZ33142.1 - 3.7e-16 59.2 0.1 7.3e-16 58.2 0.1 1.5 1 0 0 1 1 1 1 Type 5 capsule protein repressor C-terminal domain Metallophos PF00149.28 AAZ33142.1 - 1.7e-13 51.5 0.0 4.5e-13 50.2 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AAZ33142.1 - 5.2e-06 26.7 0.0 0.00017 21.8 0.0 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Peripla_BP_2 PF01497.18 AAZ33143.1 - 1.9e-41 142.2 0.0 2.6e-41 141.8 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein DeoC PF01791.9 AAZ33144.1 - 9.8e-23 81.0 0.0 1.2e-22 80.7 0.0 1.0 1 0 0 1 1 1 1 DeoC/LacD family aldolase 4HFCP_synth PF04476.13 AAZ33144.1 - 0.0015 18.3 0.1 0.0021 17.8 0.1 1.2 1 0 0 1 1 1 1 4-HFC-P synthase Asparaginase_C PF17763.1 AAZ33144.1 - 0.077 13.2 0.1 6.9 6.9 0.0 2.3 1 1 1 2 2 2 0 Glutaminase/Asparaginase C-terminal domain S4 PF01479.25 AAZ33144.1 - 0.13 12.0 0.4 5.7 6.7 0.1 2.6 1 1 1 2 2 2 0 S4 domain Epimerase PF01370.21 AAZ33145.1 - 4.4e-33 114.7 0.0 5.3e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 AAZ33145.1 - 1.4e-28 99.7 0.0 1.8e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 AAZ33145.1 - 8.7e-16 58.3 0.0 1.2e-15 57.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 AAZ33145.1 - 2.3e-15 56.5 0.0 9.7e-14 51.1 0.0 2.3 1 1 1 2 2 2 1 Male sterility protein GDP_Man_Dehyd PF16363.5 AAZ33145.1 - 9.5e-13 48.2 0.0 3.8e-12 46.3 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 AAZ33145.1 - 3.6e-10 39.4 0.0 4.9e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 AAZ33145.1 - 1.5e-08 34.5 0.0 2e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 AAZ33145.1 - 0.00014 21.4 0.0 0.00024 20.6 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Ldh_1_N PF00056.23 AAZ33145.1 - 0.0048 17.0 0.0 0.0092 16.1 0.0 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 AAZ33145.1 - 0.0052 16.0 0.0 0.016 14.3 0.0 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein LysR_substrate PF03466.20 AAZ33146.1 - 1.5e-18 67.0 0.9 2.3e-18 66.4 0.9 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ33146.1 - 3.7e-17 62.0 0.3 7.4e-17 61.1 0.3 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family Acyl-CoA_dh_C PF12806.7 AAZ33147.1 - 3.1e-30 104.9 0.0 1e-29 103.2 0.0 1.9 2 0 0 2 2 2 1 Acetyl-CoA dehydrogenase C-terminal like Acyl-CoA_dh_1 PF00441.24 AAZ33147.1 - 6.1e-18 65.5 0.0 5e-17 62.5 0.0 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 AAZ33147.1 - 4.6e-14 52.4 0.0 8.3e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 AAZ33147.1 - 3.2e-11 43.9 0.0 7.1e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain AcylCoA_DH_N PF12418.8 AAZ33147.1 - 3.6e-07 30.1 0.1 8.1e-07 29.0 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase N terminal Acyl-CoA_dh_2 PF08028.11 AAZ33147.1 - 0.0013 19.0 0.0 0.0043 17.3 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain SelB-wing_3 PF09107.11 AAZ33147.1 - 0.12 12.0 0.0 0.34 10.6 0.0 1.7 1 0 0 1 1 1 0 Elongation factor SelB, winged helix NAD_kinase PF01513.21 AAZ33148.1 - 1.5e-69 234.4 0.2 2.9e-69 233.5 0.2 1.4 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 AAZ33148.1 - 0.0022 17.6 0.1 0.0035 16.9 0.1 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Phage_integrase PF00589.22 AAZ33149.1 - 0.0002 21.2 0.1 0.0003 20.6 0.1 1.3 1 0 0 1 1 1 1 Phage integrase family Apolipo_F PF15148.6 AAZ33149.1 - 0.18 11.3 0.1 0.79 9.2 0.0 2.0 2 1 0 2 2 2 0 Apolipoprotein F HlyD_D23 PF16576.5 AAZ33150.1 - 8.6e-16 57.8 2.6 8.6e-16 57.8 2.6 1.8 2 0 0 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AAZ33150.1 - 1.4e-12 48.3 3.4 6.5e-08 33.2 0.2 3.0 3 1 0 3 3 3 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AAZ33150.1 - 3.2e-09 36.5 11.7 2.3e-07 30.6 0.5 3.4 4 0 0 4 4 4 2 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AAZ33150.1 - 0.00014 21.6 0.1 0.43 10.4 0.2 2.5 2 0 0 2 2 2 2 Biotin-requiring enzyme PTS_EIIA_1 PF00358.20 AAZ33150.1 - 0.0002 21.1 0.0 0.06 13.1 0.0 2.4 2 0 0 2 2 2 2 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 YqfD PF06898.11 AAZ33150.1 - 0.017 14.0 0.3 0.16 10.8 0.1 2.1 1 1 0 2 2 2 0 Putative stage IV sporulation protein YqfD OEP PF02321.18 AAZ33150.1 - 0.089 12.6 11.1 0.17 11.7 11.1 1.4 1 0 0 1 1 1 0 Outer membrane efflux protein PASTA PF03793.19 AAZ33150.1 - 0.096 12.6 0.5 0.75 9.7 0.2 2.6 2 0 0 2 2 2 0 PASTA domain T2SSE PF00437.20 AAZ33151.1 - 1.5e-47 161.9 0.2 6.3e-47 159.9 0.2 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_29 PF13555.6 AAZ33151.1 - 5e-05 23.0 0.0 9.1e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AAZ33151.1 - 0.0002 21.6 0.1 0.00049 20.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 AAZ33151.1 - 0.00046 20.7 0.0 0.00091 19.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain DAP3 PF10236.9 AAZ33151.1 - 0.0013 18.0 0.0 0.011 14.9 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 AAZ33151.1 - 0.0013 19.1 0.0 0.0029 18.0 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 AAZ33151.1 - 0.0035 17.7 0.7 0.015 15.6 0.6 2.2 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.18 AAZ33151.1 - 0.0044 16.4 0.1 0.0086 15.5 0.1 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_30 PF13604.6 AAZ33151.1 - 0.006 16.3 0.2 0.033 13.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 AAZ33151.1 - 0.008 16.2 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_14 PF13173.6 AAZ33151.1 - 0.011 15.7 0.0 0.024 14.7 0.0 1.7 2 0 0 2 2 1 0 AAA domain DUF87 PF01935.17 AAZ33151.1 - 0.013 15.6 0.1 0.048 13.8 0.0 1.7 1 1 0 1 1 1 0 Helicase HerA, central domain NTPase_1 PF03266.15 AAZ33151.1 - 0.015 15.3 0.4 0.33 10.8 0.1 2.3 1 1 1 2 2 2 0 NTPase ABC_tran PF00005.27 AAZ33151.1 - 0.015 15.8 0.0 0.023 15.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter SRP54 PF00448.22 AAZ33151.1 - 0.015 14.9 0.0 0.032 13.8 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_27 PF13514.6 AAZ33151.1 - 0.015 14.9 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 AAZ33151.1 - 0.016 14.5 0.0 0.027 13.7 0.0 1.4 1 1 0 1 1 1 0 Zeta toxin cobW PF02492.19 AAZ33151.1 - 0.027 14.0 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 AAZ33151.1 - 0.031 14.1 0.0 0.067 13.0 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein TK PF00265.18 AAZ33151.1 - 0.032 14.1 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 Thymidine kinase NACHT PF05729.12 AAZ33151.1 - 0.04 13.8 0.0 0.4 10.6 0.0 2.5 3 0 0 3 3 3 0 NACHT domain AAA_18 PF13238.6 AAZ33151.1 - 0.044 14.3 0.0 0.078 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 AAZ33151.1 - 0.047 12.6 0.0 0.099 11.5 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain SMC_N PF02463.19 AAZ33151.1 - 0.061 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA PF00004.29 AAZ33151.1 - 0.061 13.7 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 AAZ33151.1 - 0.079 12.7 0.2 0.18 11.6 0.1 1.6 1 1 0 2 2 2 0 AAA domain Rad17 PF03215.15 AAZ33151.1 - 0.11 12.5 0.1 0.22 11.4 0.1 1.5 1 1 0 1 1 1 0 Rad17 P-loop domain AAA_25 PF13481.6 AAZ33151.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AAZ33151.1 - 0.12 12.5 0.1 0.28 11.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 AAZ33151.1 - 0.14 11.7 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Polyketide_cyc PF03364.20 AAZ33152.1 - 3.4e-20 72.6 0.1 4e-20 72.3 0.1 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 AAZ33152.1 - 8.3e-07 29.4 0.0 1.1e-06 29.0 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF4269 PF14091.6 AAZ33153.1 - 0.011 15.9 0.2 0.023 14.9 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4269) PMSR PF01625.21 AAZ33154.1 - 1.9e-63 213.2 0.3 2.2e-63 213.0 0.3 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Transgly PF00912.22 AAZ33155.1 - 1.1e-46 158.5 0.0 1.4e-46 158.2 0.0 1.1 1 0 0 1 1 1 1 Transglycosylase Phage_integrase PF00589.22 AAZ33156.1 - 4.9e-24 85.0 0.0 8.3e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 AAZ33156.1 - 1.1e-09 38.5 0.4 2.3e-09 37.4 0.4 1.5 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 AAZ33156.1 - 0.00019 21.8 0.0 0.00032 21.1 0.0 1.3 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Transposase_mut PF00872.18 AAZ33157.1 - 1.5e-117 392.7 0.0 1.9e-117 392.3 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ33157.1 - 7.7e-05 23.0 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain DUF4844 PF16133.5 AAZ33157.1 - 0.23 12.0 0.0 0.55 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) TetR_N PF00440.23 AAZ33159.1 - 1.1e-15 57.1 1.3 1.4e-15 56.8 0.3 1.7 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.6 AAZ33159.1 - 2e-05 24.8 0.0 4.7e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 BetI-type transcriptional repressor, C-terminal TetR_C_11 PF16859.5 AAZ33159.1 - 0.0079 16.5 0.2 1.3 9.4 0.0 2.5 1 1 0 2 2 2 2 Tetracyclin repressor-like, C-terminal domain LacI PF00356.21 AAZ33159.1 - 0.026 14.3 0.2 0.051 13.4 0.2 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family TetR_C_7 PF14246.6 AAZ33159.1 - 0.03 14.3 0.1 0.087 12.9 0.0 1.8 2 0 0 2 2 2 0 AefR-like transcriptional repressor, C-terminal domain Spindle_Spc25 PF08234.12 AAZ33159.1 - 0.13 12.5 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Chromosome segregation protein Spc25 LysR_substrate PF03466.20 AAZ33160.1 - 6e-46 156.5 0.4 8.7e-46 155.9 0.4 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ33160.1 - 4.3e-17 61.8 0.0 7.7e-17 61.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 AAZ33160.1 - 0.0055 16.6 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 MarR family BPD_transp_1 PF00528.22 AAZ33161.1 - 1.5e-16 60.7 20.9 1.5e-16 60.7 20.9 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component Multi_Drug_Res PF00893.19 AAZ33162.1 - 4.3e-11 43.3 4.5 8.6e-11 42.4 4.5 1.4 1 1 0 1 1 1 1 Small Multidrug Resistance protein EamA PF00892.20 AAZ33162.1 - 1.2e-08 35.2 7.8 5.8e-08 33.0 7.8 1.8 1 1 0 1 1 1 1 EamA-like transporter family TMEM234 PF10639.9 AAZ33162.1 - 0.00026 21.0 0.1 0.00032 20.7 0.1 1.2 1 0 0 1 1 1 1 Putative transmembrane family 234 UPF0060 PF02694.15 AAZ33162.1 - 0.0023 18.1 4.9 0.0033 17.6 4.9 1.4 1 1 0 1 1 1 1 Uncharacterised BCR, YnfA/UPF0060 family Na_H_antiporter PF03553.14 AAZ33162.1 - 0.024 13.9 0.3 0.024 13.9 0.3 1.1 1 0 0 1 1 1 0 Na+/H+ antiporter family Harakiri PF15196.6 AAZ33162.1 - 0.031 14.7 1.5 0.045 14.2 1.5 1.3 1 0 0 1 1 1 0 Activator of apoptosis harakiri DUF202 PF02656.15 AAZ33162.1 - 0.25 11.8 6.5 0.7 10.4 4.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF202) PAS_9 PF13426.7 AAZ33163.1 - 2.6e-19 69.4 0.0 5e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 PAS domain Response_reg PF00072.24 AAZ33163.1 - 5.7e-18 65.1 0.0 1.1e-17 64.2 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 AAZ33163.1 - 1.8e-15 57.4 0.0 5e-15 56.0 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 AAZ33163.1 - 1.8e-09 37.8 0.0 5.2e-09 36.3 0.0 1.8 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 AAZ33163.1 - 6.8e-09 35.7 0.1 1.8e-08 34.4 0.0 1.8 2 0 0 2 2 2 1 PAS fold HisKA PF00512.25 AAZ33163.1 - 5.2e-06 26.4 0.1 2.6e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 AAZ33163.1 - 1.5e-05 25.2 0.0 8.7e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 AAZ33163.1 - 0.00012 22.0 0.0 0.00029 20.8 0.0 1.7 1 0 0 1 1 1 1 PAS domain SPOB_a PF14689.6 AAZ33163.1 - 0.024 14.3 0.0 0.059 13.1 0.0 1.6 1 0 0 1 1 1 0 Sensor_kinase_SpoOB-type, alpha-helical domain HisKA_4TM PF16926.5 AAZ33163.1 - 0.12 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Archaeal 4TM region of histidine kinase CxxCxxCC PF03692.15 AAZ33164.1 - 9e-09 35.9 7.4 2.1e-08 34.7 7.4 1.6 1 1 0 1 1 1 1 Putative zinc- or iron-chelating domain ABC_tran PF00005.27 AAZ33165.1 - 1.3e-30 106.6 0.0 1.9e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 AAZ33165.1 - 1.2e-20 73.7 0.5 1.9e-20 73.1 0.5 1.3 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_22 PF13401.6 AAZ33165.1 - 1.3e-05 25.5 0.1 7.5e-05 23.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 AAZ33165.1 - 0.00052 19.5 0.2 0.0025 17.3 0.2 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AAZ33165.1 - 0.0018 18.2 0.1 0.026 14.4 0.1 2.1 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AAZ33165.1 - 0.0063 16.2 0.1 0.011 15.4 0.1 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 AAZ33165.1 - 0.011 15.9 0.1 0.027 14.6 0.1 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 AAZ33165.1 - 0.062 13.7 1.1 0.092 13.1 1.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 AAZ33165.1 - 0.066 13.1 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 AAZ33165.1 - 0.12 13.0 0.0 0.23 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AAZ33165.1 - 0.15 11.7 0.2 13 5.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 AAZ33165.1 - 0.23 10.6 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain PolyA_pol_arg_C PF12626.7 AAZ33166.1 - 8.2e-42 142.0 3.0 3.9e-41 139.9 0.7 2.4 2 0 0 2 2 2 1 Polymerase A arginine-rich C-terminus PolyA_pol PF01743.20 AAZ33166.1 - 3.6e-40 137.3 0.4 6.5e-40 136.5 0.4 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 AAZ33166.1 - 2.1e-19 69.0 0.3 2.1e-19 69.0 0.3 1.8 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A Flagellin_N PF00669.20 AAZ33167.1 - 9.7e-40 135.9 21.1 9.7e-40 135.9 21.1 2.7 2 1 0 2 2 2 1 Bacterial flagellin N-terminal helical region Flagellin_C PF00700.21 AAZ33167.1 - 4.1e-24 84.8 11.3 4.1e-24 84.8 11.3 4.1 2 1 0 3 3 3 1 Bacterial flagellin C-terminal helical region CCDC-167 PF15188.6 AAZ33167.1 - 0.051 13.9 1.7 1.3 9.4 0.3 2.8 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 IZUMO PF15005.6 AAZ33167.1 - 0.36 11.3 3.1 5.6 7.5 0.3 2.3 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated DUF3829 PF12889.7 AAZ33167.1 - 0.4 10.1 8.4 1.7 8.1 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) Med10 PF09748.9 AAZ33167.1 - 0.6 10.1 8.9 13 5.8 5.8 3.3 2 1 0 2 2 2 0 Transcription factor subunit Med10 of Mediator complex DUF2408 PF10303.9 AAZ33167.1 - 0.85 10.2 4.6 5.9 7.5 0.6 2.6 2 2 0 2 2 2 0 Protein of unknown function (DUF2408) TMF_TATA_bd PF12325.8 AAZ33167.1 - 1.4 9.1 7.2 1.5 9.1 0.3 2.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Seryl_tRNA_N PF02403.22 AAZ33167.1 - 1.9 8.8 8.0 0.26 11.5 1.0 2.6 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain THOC7 PF05615.13 AAZ33167.1 - 2.4 8.5 10.8 3.7 7.8 1.1 3.0 2 2 1 3 3 3 0 Tho complex subunit 7 ABC_membrane PF00664.23 AAZ33168.1 - 9.4e-54 182.9 11.0 1.2e-53 182.5 11.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 AAZ33168.1 - 4.4e-32 111.5 0.0 1.1e-31 110.2 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AAZ33168.1 - 4.9e-08 32.7 0.0 3.5e-05 23.3 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAZ33168.1 - 2.7e-05 23.8 0.0 9.3e-05 22.1 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AAZ33168.1 - 0.00044 20.2 0.0 0.00091 19.2 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 AAZ33168.1 - 0.00067 20.1 0.6 0.00067 20.1 0.6 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 AAZ33168.1 - 0.00085 19.2 0.5 0.032 14.0 0.0 2.3 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 AAZ33168.1 - 0.0021 18.4 0.2 0.039 14.2 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.6 AAZ33168.1 - 0.0073 16.8 0.0 0.023 15.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain DUF2116 PF09889.9 AAZ33168.1 - 0.019 15.0 0.2 0.062 13.3 0.2 1.9 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Guanylate_kin PF00625.21 AAZ33168.1 - 0.024 14.3 0.0 0.19 11.4 0.0 2.1 2 0 0 2 2 2 0 Guanylate kinase AAA_15 PF13175.6 AAZ33168.1 - 0.055 13.2 0.0 0.086 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain PepSY_2 PF13670.6 AAZ33169.1 - 8.7e-32 109.0 0.1 9.4e-32 108.9 0.1 1.0 1 0 0 1 1 1 1 Peptidase propeptide and YPEB domain PepSY PF03413.19 AAZ33169.1 - 0.027 15.0 0.4 0.036 14.6 0.4 1.2 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain ECH_1 PF00378.20 AAZ33170.1 - 3.8e-53 180.4 0.0 4.7e-53 180.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AAZ33170.1 - 4.5e-25 88.9 0.0 5.3e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase TraG_N PF07916.11 AAZ33171.1 - 5.2e-85 286.0 9.8 6.1e-85 285.8 9.8 1.0 1 0 0 1 1 1 1 TraG-like protein, N-terminal region ADH_N PF08240.12 AAZ33172.1 - 2.5e-27 94.9 1.1 4.7e-27 94.0 1.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AAZ33172.1 - 8.1e-06 25.8 0.2 1.8e-05 24.7 0.2 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 AAZ33172.1 - 2.7e-05 23.6 1.8 5.1e-05 22.7 1.8 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.21 AAZ33172.1 - 0.0004 20.5 0.2 0.00075 19.6 0.2 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 AAZ33172.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.19 AAZ33172.1 - 0.15 11.3 0.5 0.23 10.6 0.5 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 AAZ33172.1 - 9.7 5.4 9.1 4.5 6.5 7.1 1.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase Isochorismatase PF00857.20 AAZ33173.1 - 8e-44 149.9 0.0 1.2e-43 149.3 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family DUF2160 PF09928.9 AAZ33174.1 - 1.4e-36 124.7 10.1 1.5e-36 124.5 10.1 1.0 1 0 0 1 1 1 1 Predicted small integral membrane protein (DUF2160) PsbN PF02468.15 AAZ33174.1 - 0.36 10.7 1.6 5.6 6.9 0.1 2.2 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) UvrC_HhH_N PF08459.11 AAZ33175.1 - 4.1e-53 179.4 0.0 1.1e-52 178.0 0.0 1.8 2 0 0 2 2 2 1 UvrC Helix-hairpin-helix N-terminal GIY-YIG PF01541.24 AAZ33175.1 - 2.9e-11 43.5 0.0 5.8e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain HHH_5 PF14520.6 AAZ33175.1 - 3e-10 40.6 0.0 6.6e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain UVR PF02151.19 AAZ33175.1 - 4.9e-08 32.5 3.0 1.3e-07 31.1 3.0 1.8 1 0 0 1 1 1 1 UvrB/uvrC motif HHH_2 PF12826.7 AAZ33175.1 - 9.7e-08 32.0 0.0 8.3e-07 29.0 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH PF00633.23 AAZ33175.1 - 4.3e-07 29.5 0.1 0.00026 20.7 0.1 2.8 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_3 PF12836.7 AAZ33175.1 - 0.033 14.5 0.4 0.73 10.1 0.1 2.6 3 0 0 3 3 3 0 Helix-hairpin-helix motif 5_3_exonuc PF01367.20 AAZ33175.1 - 0.047 14.3 0.0 0.17 12.5 0.0 1.9 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold Transposase_mut PF00872.18 AAZ33176.1 - 5.8e-117 390.8 0.0 7.3e-117 390.4 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ33176.1 - 7.8e-05 23.0 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain DUF4844 PF16133.5 AAZ33176.1 - 0.23 12.0 0.0 0.55 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) PolyA_pol PF01743.20 AAZ33177.1 - 3.6e-18 66.2 0.0 7.9e-18 65.1 0.0 1.6 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 AAZ33177.1 - 3.6e-13 49.1 0.2 7.2e-13 48.1 0.2 1.5 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A HD PF01966.22 AAZ33177.1 - 8e-09 35.8 2.9 1.7e-08 34.7 0.5 2.4 2 1 0 2 2 2 1 HD domain OmpA PF00691.20 AAZ33178.1 - 1.7e-22 79.6 0.8 1.7e-22 79.6 0.8 1.6 2 0 0 2 2 2 1 OmpA family Gly-zipper_Omp PF13488.6 AAZ33178.1 - 7.4e-09 35.5 16.6 1.2e-08 34.8 15.9 1.7 2 0 0 2 2 2 1 Glycine zipper Gly-zipper_YMGG PF13441.6 AAZ33178.1 - 1.2e-05 24.9 17.6 2.2e-05 24.1 17.6 1.4 1 0 0 1 1 1 1 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.15 AAZ33178.1 - 0.00052 19.8 18.0 0.00097 19.0 18.0 1.4 1 0 0 1 1 1 1 Glycine zipper 2TM domain LPAM_1 PF08139.12 AAZ33178.1 - 0.0013 19.1 0.8 0.0013 19.1 0.8 2.0 2 0 0 2 2 2 1 Prokaryotic membrane lipoprotein lipid attachment site Gly-zipper_OmpA PF13436.6 AAZ33178.1 - 0.016 15.0 18.4 0.035 13.9 18.4 1.6 1 1 0 1 1 1 0 Glycine-zipper domain DUF3482 PF11981.8 AAZ33178.1 - 0.041 13.3 9.5 0.067 12.6 9.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Ribosomal_S11 PF00411.19 AAZ33178.1 - 0.14 12.6 4.3 0.26 11.7 0.1 2.7 1 1 2 3 3 3 0 Ribosomal protein S11 CreA PF05981.12 AAZ33179.1 - 3.8e-58 195.1 0.0 4.4e-58 194.9 0.0 1.0 1 0 0 1 1 1 1 CreA protein ABC_membrane PF00664.23 AAZ33181.1 - 2.8e-42 145.3 13.4 3.6e-42 144.9 13.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region Peptidase_C39 PF03412.15 AAZ33181.1 - 2.6e-34 117.9 0.0 4.1e-34 117.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase C39 family ABC_tran PF00005.27 AAZ33181.1 - 4.3e-29 101.8 0.0 6.8e-29 101.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AAZ33181.1 - 1.5e-07 31.1 0.2 5.3e-05 22.8 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain Peptidase_C70 PF12385.8 AAZ33181.1 - 4e-05 23.6 0.1 0.00013 22.0 0.1 1.8 1 1 0 1 1 1 1 Papain-like cysteine protease AvrRpt2 AAA_29 PF13555.6 AAZ33181.1 - 0.00016 21.3 0.0 0.00049 19.8 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AAZ33181.1 - 0.0012 18.8 0.0 0.0026 17.7 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 AAZ33181.1 - 0.0015 18.4 0.1 1.9 8.2 0.2 3.1 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 AAZ33181.1 - 0.054 13.1 0.0 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 AAZ33181.1 - 0.057 13.5 0.3 0.12 12.4 0.3 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Guanylate_cyc_2 PF09778.9 AAZ33181.1 - 0.061 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Guanylylate cyclase AAA_22 PF13401.6 AAZ33181.1 - 0.13 12.5 2.4 1.9 8.8 0.1 2.6 3 0 0 3 3 3 0 AAA domain SbcCD_C PF13558.6 AAZ33181.1 - 0.18 12.1 1.2 0.59 10.4 0.1 2.4 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit Peptidase_C39_2 PF13529.6 AAZ33181.1 - 0.2 12.2 0.3 1.1 9.8 0.0 2.0 2 0 0 2 2 2 0 Peptidase_C39 like family AAA_23 PF13476.6 AAZ33181.1 - 0.24 11.9 0.0 0.41 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF2252 PF10009.9 AAZ33182.1 - 1.1e-87 294.6 0.0 1.5e-87 294.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2252) APH PF01636.23 AAZ33182.1 - 0.0028 17.6 1.1 0.0037 17.2 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Ribosomal_S13 PF00416.22 AAZ33183.1 - 1.9e-34 118.8 5.9 1.5e-32 112.7 5.9 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 AAZ33183.1 - 0.00039 19.3 0.0 0.00042 19.2 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_3 PF12836.7 AAZ33183.1 - 0.0054 17.0 0.1 0.14 12.5 0.1 2.4 1 1 0 1 1 1 1 Helix-hairpin-helix motif DNA_pol_lambd_f PF10391.9 AAZ33183.1 - 0.016 15.0 0.1 0.031 14.1 0.1 1.8 1 1 0 1 1 1 0 Fingers domain of DNA polymerase lambda HHH_6 PF14579.6 AAZ33183.1 - 0.017 15.4 0.1 2.8 8.3 0.0 2.2 1 1 1 2 2 2 0 Helix-hairpin-helix motif GSHPx PF00255.19 AAZ33184.1 - 2.4e-22 78.6 0.0 3.3e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 AAZ33184.1 - 0.00081 19.3 0.1 0.0024 17.8 0.1 1.7 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AAZ33184.1 - 0.0056 16.4 0.1 0.016 14.9 0.1 1.8 1 1 0 1 1 1 1 Redoxin DnaJ PF00226.31 AAZ33187.1 - 1.2e-05 25.3 0.2 4.2e-05 23.6 0.2 1.9 1 0 0 1 1 1 1 DnaJ domain Topoisom_I_N PF02919.15 AAZ33187.1 - 0.019 14.5 0.9 0.05 13.1 0.9 1.7 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Phasin_2 PF09361.10 AAZ33187.1 - 0.05 13.9 2.8 0.054 13.8 0.0 2.5 3 0 0 3 3 3 0 Phasin protein T3SS_basalb_I PF17001.5 AAZ33187.1 - 0.31 11.6 10.9 4.3 8.0 0.1 3.6 2 1 1 3 3 3 0 Type III secretion basal body protein I, YscI, HrpB, PscI ABATE PF07336.11 AAZ33187.1 - 1.5 9.5 5.6 7.8 7.2 0.1 2.8 3 0 0 3 3 3 0 Putative stress-induced transcription regulator HTH_37 PF13744.6 AAZ33187.1 - 3.9 7.5 9.8 1.1 9.2 1.6 3.7 3 0 0 3 3 3 0 Helix-turn-helix domain DASH_Hsk3 PF08227.11 AAZ33187.1 - 6.3 7.2 8.4 26 5.3 0.0 4.2 4 0 0 4 4 4 0 DASH complex subunit Hsk3 like NUDIX PF00293.28 AAZ33188.1 - 4.9e-18 65.4 0.0 7.6e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DUF448 PF04296.13 AAZ33188.1 - 0.12 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF448) Sugar_tr PF00083.24 AAZ33189.1 - 1.9e-111 373.1 19.8 2.2e-111 372.9 19.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 AAZ33189.1 - 9e-35 120.2 30.6 9e-35 120.2 30.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 AAZ33189.1 - 7.6e-09 34.5 2.9 7.6e-09 34.5 2.9 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 AAZ33189.1 - 2.5e-05 23.3 10.0 0.021 13.7 0.1 3.1 2 2 1 3 3 3 2 MFS_1 like family DR2241 PF18069.1 AAZ33189.1 - 0.15 12.0 0.1 0.25 11.2 0.1 1.3 1 0 0 1 1 1 0 DR2241 stabilising domain Tmemb_55A PF09788.9 AAZ33189.1 - 0.46 9.5 3.4 0.86 8.6 3.4 1.3 1 0 0 1 1 1 0 Transmembrane protein 55A SBP_bac_8 PF13416.6 AAZ33190.1 - 8.2e-42 143.9 7.0 1.2e-41 143.4 7.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AAZ33190.1 - 3.3e-15 56.9 12.9 5.8e-15 56.0 12.7 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AAZ33190.1 - 3.9e-13 49.4 1.3 6.6e-13 48.6 1.3 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 AAZ33190.1 - 0.0084 15.9 0.3 0.014 15.1 0.3 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein Peptidase_S9_N PF02897.15 AAZ33191.1 - 3.5e-77 260.0 0.0 4.5e-77 259.6 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 AAZ33191.1 - 3.5e-70 235.8 0.0 5.1e-70 235.3 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 AAZ33191.1 - 6.3e-05 22.4 0.0 0.00014 21.3 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 AAZ33191.1 - 0.00036 20.2 0.1 0.086 12.4 0.0 2.4 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 AAZ33191.1 - 0.0013 18.4 0.0 0.0041 16.8 0.0 1.9 1 1 0 1 1 1 1 Putative esterase PAE PF03283.13 AAZ33191.1 - 0.0024 17.1 0.0 0.0038 16.4 0.0 1.2 1 0 0 1 1 1 1 Pectinacetylesterase Abhydrolase_1 PF00561.20 AAZ33191.1 - 0.003 17.2 0.0 0.024 14.3 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold PD40 PF07676.12 AAZ33191.1 - 0.031 14.2 1.6 0.13 12.2 0.1 2.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat HTH_Tnp_1 PF01527.20 AAZ33192.1 - 6.3e-10 39.2 0.1 6.8e-10 39.1 0.1 1.0 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 AAZ33192.1 - 0.032 14.0 0.0 0.037 13.8 0.0 1.2 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 AAZ33192.1 - 0.062 13.4 0.0 0.074 13.2 0.0 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain Mig-14 PF07395.11 AAZ33193.1 - 1.4e-142 473.7 0.0 1.7e-142 473.5 0.0 1.0 1 0 0 1 1 1 1 Mig-14 Acetyltransf_6 PF13480.7 AAZ33193.1 - 4.6e-10 39.8 1.0 1.2e-09 38.5 0.1 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DAHP_synth_1 PF00793.20 AAZ33194.1 - 9.6e-75 251.0 0.0 1.1e-74 250.8 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family PapD_N PF00345.20 AAZ33195.1 - 1.2e-38 131.8 0.0 3.8e-38 130.2 0.0 1.7 2 0 0 2 2 2 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain PapD_C PF02753.17 AAZ33195.1 - 6.1e-14 52.1 0.0 1.1e-12 48.2 0.0 2.4 1 1 1 2 2 2 1 Pili assembly chaperone PapD, C-terminal domain DUF4399 PF14347.6 AAZ33196.1 - 3e-39 133.3 0.5 3.8e-39 133.0 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4399) PEGA PF08308.11 AAZ33196.1 - 0.0034 17.2 0.5 0.58 10.1 0.0 2.6 2 1 1 3 3 3 2 PEGA domain Lipin_N PF04571.14 AAZ33196.1 - 0.025 14.5 0.0 0.044 13.8 0.0 1.6 1 1 0 1 1 1 0 lipin, N-terminal conserved region BiPBP_C PF06832.12 AAZ33196.1 - 0.09 12.8 0.1 1.2 9.3 0.1 2.1 1 1 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family Peptidase_M48 PF01435.18 AAZ33197.1 - 1.6e-37 129.2 0.5 2e-37 128.9 0.0 1.4 2 0 0 2 2 2 1 Peptidase family M48 Peptidase_M56 PF05569.11 AAZ33197.1 - 0.00016 20.9 0.1 0.00046 19.5 0.0 1.8 1 1 1 2 2 2 1 BlaR1 peptidase M56 SprT-like PF10263.9 AAZ33197.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 SprT-like family LPG_synthase_TM PF03706.13 AAZ33197.1 - 0.13 11.8 8.2 0.15 11.6 0.5 2.1 2 0 0 2 2 2 0 Lysylphosphatidylglycerol synthase TM region DUF3681 PF12442.8 AAZ33197.1 - 0.14 12.7 2.6 0.37 11.3 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3681) TssN PF17555.2 AAZ33197.1 - 2 7.8 9.3 0.1 12.0 2.0 1.9 2 0 0 2 2 2 0 Type VI secretion system, TssN Yip1 PF04893.17 AAZ33197.1 - 5.1 6.8 12.7 2.5 7.8 0.3 2.2 2 0 0 2 2 2 0 Yip1 domain FAD_binding_7 PF03441.14 AAZ33198.1 - 4.2e-80 268.0 0.1 7.3e-80 267.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 AAZ33198.1 - 9.8e-45 152.5 0.2 1.6e-44 151.8 0.2 1.3 1 0 0 1 1 1 1 DNA photolyase CAP59_mtransfer PF11735.8 AAZ33198.1 - 0.0015 18.3 0.0 0.0028 17.4 0.0 1.4 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 DUF3243 PF11588.8 AAZ33198.1 - 0.047 14.0 0.0 0.2 12.0 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3243) Amidinotransf PF02274.17 AAZ33199.1 - 1e-07 31.4 0.0 0.0028 16.8 0.0 3.1 3 1 0 3 3 3 2 Amidinotransferase Usp PF00582.26 AAZ33200.1 - 1.8e-33 116.0 0.3 2.1e-33 115.8 0.3 1.0 1 0 0 1 1 1 1 Universal stress protein family TPR_6 PF13174.6 AAZ33200.1 - 0.027 15.1 0.9 0.064 13.9 0.9 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat BRCT PF00533.26 AAZ33200.1 - 0.028 14.8 0.0 0.076 13.4 0.0 1.7 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain DXP_reductoisom PF02670.16 AAZ33200.1 - 0.077 13.7 0.1 0.1 13.3 0.1 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase ABC_tran PF00005.27 AAZ33201.1 - 1.8e-17 64.1 0.0 6.7e-17 62.3 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 AAZ33201.1 - 3.2e-06 26.8 0.1 6.2e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AAZ33201.1 - 0.00067 20.2 0.0 0.00084 19.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAZ33201.1 - 0.0012 19.3 0.0 0.0016 18.8 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 AAZ33201.1 - 0.0016 18.3 0.1 0.0021 18.0 0.1 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 AAZ33201.1 - 0.0032 17.8 0.0 0.0078 16.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 AAZ33201.1 - 0.0075 15.7 0.1 0.039 13.4 0.0 1.9 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 AAZ33201.1 - 0.017 15.1 0.0 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_15 PF13175.6 AAZ33201.1 - 0.018 14.8 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.15 AAZ33201.1 - 0.088 12.7 0.5 1 9.2 0.1 2.1 2 0 0 2 2 2 0 NTPase NACHT PF05729.12 AAZ33201.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 AAZ33201.1 - 0.13 12.3 0.1 0.26 11.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 AAZ33201.1 - 0.15 12.2 0.0 0.37 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AAZ33201.1 - 0.16 11.5 0.1 0.33 10.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain Rieske PF00355.26 AAZ33202.1 - 2.6e-19 68.9 0.2 3.1e-19 68.7 0.2 1.0 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 AAZ33202.1 - 4.6e-10 39.4 0.0 5.3e-10 39.2 0.0 1.0 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain gag-asp_proteas PF13975.6 AAZ33203.1 - 4.3e-24 84.9 0.8 6.1e-24 84.4 0.8 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 AAZ33203.1 - 3.1e-21 75.8 1.8 4.6e-21 75.3 1.8 1.2 1 0 0 1 1 1 1 Aspartyl protease RNase_PH PF01138.21 AAZ33204.1 - 8.8e-27 94.2 0.0 1.6e-26 93.3 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 AAZ33204.1 - 2.3e-10 40.4 0.1 6e-10 39.0 0.0 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 BrnA_antitoxin PF14384.6 AAZ33204.1 - 0.044 14.3 0.0 3.3 8.3 0.0 2.5 2 0 0 2 2 2 0 BrnA antitoxin of type II toxin-antitoxin system Lactonase PF10282.9 AAZ33205.1 - 1.8e-05 24.2 0.0 0.094 11.9 0.0 3.8 3 2 1 4 4 4 3 Lactonase, 7-bladed beta-propeller PD40 PF07676.12 AAZ33205.1 - 0.00013 21.8 0.1 0.18 11.8 0.0 4.0 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat SGL PF08450.12 AAZ33205.1 - 0.0037 16.9 0.1 0.97 9.0 0.0 3.5 1 1 2 4 4 4 1 SMP-30/Gluconolactonase/LRE-like region WD40 PF00400.32 AAZ33205.1 - 0.018 15.9 0.4 3.7 8.6 0.0 3.9 4 2 0 4 4 4 0 WD domain, G-beta repeat UBA_5 PF16577.5 AAZ33205.1 - 0.066 13.4 0.0 14 5.9 0.0 2.6 2 0 0 2 2 2 0 UBA domain PPDK_N PF01326.19 AAZ33207.1 - 1.5e-08 34.3 0.1 0.0046 16.3 0.0 3.0 2 1 0 3 3 3 2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 AAZ33207.1 - 0.00023 20.8 0.0 0.00054 19.6 0.0 1.7 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain Hydrolase_4 PF12146.8 AAZ33207.1 - 0.024 13.9 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 FliO PF04347.13 AAZ33208.1 - 6.2e-19 68.1 0.6 1.1e-18 67.3 0.4 1.5 2 0 0 2 2 2 1 Flagellar biosynthesis protein, FliO FeoA PF04023.14 AAZ33208.1 - 0.15 12.4 0.9 0.7 10.2 0.3 2.1 1 1 0 2 2 2 0 FeoA domain IstB_IS21 PF01695.17 AAZ33209.1 - 5.6e-62 208.6 0.1 8.3e-62 208.1 0.1 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein Bac_DnaA PF00308.18 AAZ33209.1 - 2.4e-06 27.5 0.0 3.4e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial dnaA protein AAA_28 PF13521.6 AAZ33209.1 - 4.2e-05 23.9 0.0 0.0002 21.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 AAZ33209.1 - 0.0013 18.2 0.1 0.0053 16.2 0.0 1.9 2 0 0 2 2 2 1 PhoH-like protein AAA PF00004.29 AAZ33209.1 - 0.0025 18.2 0.0 0.0047 17.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 AAZ33209.1 - 0.0041 16.9 0.0 0.0064 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 AAZ33209.1 - 0.017 15.5 0.1 0.046 14.1 0.1 1.8 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 AAZ33209.1 - 0.023 14.1 0.0 0.041 13.2 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.6 AAZ33209.1 - 0.025 15.0 0.1 0.05 14.0 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain A_deamin PF02137.18 AAZ33209.1 - 0.039 13.4 0.0 0.067 12.6 0.0 1.3 1 0 0 1 1 1 0 Adenosine-deaminase (editase) domain Parvo_NS1 PF01057.17 AAZ33209.1 - 0.043 12.9 0.2 1.4 7.9 0.0 2.3 1 1 1 2 2 2 0 Parvovirus non-structural protein NS1 FtsK_SpoIIIE PF01580.18 AAZ33209.1 - 0.044 13.1 0.0 0.078 12.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Mg_chelatase PF01078.21 AAZ33209.1 - 0.052 12.9 0.0 0.13 11.6 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 AAZ33209.1 - 0.06 13.6 0.4 0.37 11.1 0.1 2.3 2 1 1 3 3 3 0 AAA domain AAA_33 PF13671.6 AAZ33209.1 - 0.073 13.2 1.6 0.27 11.4 1.6 2.1 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AAZ33209.1 - 0.076 12.7 0.0 0.2 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 AAZ33209.1 - 0.096 12.2 0.0 0.44 10.0 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region Wzt_C PF14524.6 AAZ33210.1 - 6.8e-34 116.9 0.0 1.4e-33 116.0 0.0 1.5 1 0 0 1 1 1 1 Wzt C-terminal domain ABC_tran PF00005.27 AAZ33210.1 - 1.1e-23 84.2 0.0 4.3e-23 82.4 0.0 1.9 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 AAZ33210.1 - 0.00029 20.5 0.1 0.00087 19.0 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 AAZ33210.1 - 0.00039 20.3 1.4 0.016 15.0 0.3 2.4 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 AAZ33210.1 - 0.001 18.8 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 AAZ33210.1 - 0.0011 18.3 0.2 0.0018 17.6 0.2 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_23 PF13476.6 AAZ33210.1 - 0.0011 19.5 0.1 0.0022 18.5 0.1 1.4 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AAZ33210.1 - 0.0015 18.5 0.0 0.0039 17.1 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 AAZ33210.1 - 0.0087 16.1 0.2 0.02 14.9 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 AAZ33210.1 - 0.011 16.0 0.4 0.077 13.3 0.4 2.0 1 1 0 1 1 1 0 AAA domain Prok_Ub PF14454.6 AAZ33210.1 - 0.014 15.0 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic Ubiquitin AAA_15 PF13175.6 AAZ33210.1 - 0.034 13.9 0.0 0.047 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.23 AAZ33210.1 - 0.036 14.1 0.0 0.057 13.5 0.0 1.3 1 0 0 1 1 1 0 Dynamin family MeaB PF03308.16 AAZ33210.1 - 0.09 11.7 0.1 0.16 10.9 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 AAZ33210.1 - 0.092 12.7 0.8 0.31 10.9 0.3 2.0 2 0 0 2 2 2 0 NTPase SMC_N PF02463.19 AAZ33210.1 - 0.11 11.9 0.7 0.46 9.9 0.1 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain CARDB PF07705.11 AAZ33210.1 - 0.12 12.6 0.0 2.5 8.4 0.0 2.7 3 0 0 3 3 3 0 CARDB Lactamase_B_2 PF12706.7 AAZ33210.1 - 0.13 11.8 0.0 8.9 5.8 0.0 2.4 2 0 0 2 2 2 0 Beta-lactamase superfamily domain Shufflon_N PF04917.12 AAZ33211.1 - 7.3e-51 173.5 31.8 3.6e-32 112.1 17.6 2.2 1 1 1 2 2 2 2 Bacterial shufflon protein, N-terminal constant region FapA PF03961.13 AAZ33211.1 - 1.2e-06 27.4 3.1 1.2e-06 27.4 3.1 1.7 2 0 0 2 2 2 1 Flagellar Assembly Protein A Bactofilin PF04519.13 AAZ33211.1 - 0.00066 19.9 11.8 0.0021 18.3 5.9 2.4 2 0 0 2 2 2 2 Polymer-forming cytoskeletal DUF748 PF05359.11 AAZ33211.1 - 0.17 12.0 1.0 0.65 10.2 0.9 2.0 1 1 0 1 1 1 0 Domain of Unknown Function (DUF748) MinC_C PF03775.16 AAZ33211.1 - 0.21 11.6 14.1 0.9 9.6 7.6 3.0 2 1 0 2 2 2 0 Septum formation inhibitor MinC, C-terminal domain Cupin_2 PF07883.11 AAZ33212.1 - 0.00011 21.9 0.1 0.00015 21.4 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_7 PF12973.7 AAZ33212.1 - 0.014 15.3 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 ChrR Cupin-like domain Pirin PF02678.16 AAZ33212.1 - 0.036 14.0 0.0 0.042 13.8 0.0 1.1 1 0 0 1 1 1 0 Pirin AraC_binding PF02311.19 AAZ33212.1 - 0.091 12.7 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain Cupin_1 PF00190.22 AAZ33212.1 - 0.15 11.7 0.1 0.65 9.6 0.1 1.9 1 1 0 1 1 1 0 Cupin AA_permease PF00324.21 AAZ33213.1 - 6.5e-115 384.5 42.3 7.3e-115 384.3 42.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 AAZ33213.1 - 3.9e-39 134.7 45.3 4.7e-39 134.4 45.3 1.0 1 0 0 1 1 1 1 Amino acid permease Arabinose_bd PF12625.7 AAZ33214.1 - 8.6e-43 146.6 5.1 1.4e-42 145.9 5.1 1.4 1 0 0 1 1 1 1 Arabinose-binding domain of AraC transcription regulator, N-term HTH_18 PF12833.7 AAZ33214.1 - 8e-14 51.7 0.7 8e-14 51.7 0.7 2.6 3 1 0 3 3 3 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAZ33214.1 - 1.6e-07 31.2 0.0 4.2e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family Sigma70_r3 PF04539.16 AAZ33214.1 - 0.16 12.0 0.0 0.37 10.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-70 region 3 AIRS PF00586.24 AAZ33216.1 - 7.7e-24 84.2 0.6 1.9e-23 82.9 0.6 1.7 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain AIRS_C PF02769.22 AAZ33216.1 - 2.1e-07 31.2 0.1 3.6e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain Amidase PF01425.21 AAZ33217.1 - 2.5e-72 244.3 0.4 4.7e-72 243.4 0.4 1.4 1 1 0 1 1 1 1 Amidase EAL PF00563.20 AAZ33218.1 - 5.7e-69 232.3 0.6 9.3e-69 231.6 0.1 1.6 2 0 0 2 2 2 1 EAL domain GGDEF PF00990.21 AAZ33218.1 - 1.7e-46 157.9 0.1 2.7e-46 157.3 0.1 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_9 PF13426.7 AAZ33218.1 - 3.4e-13 49.7 0.0 1.1e-12 48.1 0.0 1.9 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 AAZ33218.1 - 2e-10 40.7 0.0 4.2e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 AAZ33218.1 - 4.7e-08 32.9 0.0 5.5e-07 29.5 0.0 2.6 2 0 0 2 2 2 1 PAS domain PAS_3 PF08447.12 AAZ33218.1 - 1.1e-07 32.1 0.2 2.3e-07 31.0 0.2 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AAZ33218.1 - 1.5e-06 28.4 0.1 1e-05 25.7 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS_7 PF12860.7 AAZ33218.1 - 0.00049 20.2 0.0 0.28 11.4 0.0 3.0 3 0 0 3 3 3 1 PAS fold GlpM PF06942.12 AAZ33218.1 - 0.14 12.6 1.5 0.39 11.2 1.5 1.8 1 0 0 1 1 1 0 GlpM protein SpoIIE PF07228.12 AAZ33219.1 - 7.3e-40 136.9 0.0 1.2e-39 136.2 0.0 1.4 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Response_reg PF00072.24 AAZ33219.1 - 1.5e-22 79.9 0.0 2.6e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c_2 PF13581.6 AAZ33219.1 - 4.5e-07 29.9 0.0 1.4e-06 28.2 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c PF02518.26 AAZ33219.1 - 0.0012 19.3 0.0 0.0027 18.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peptidase_S66 PF02016.15 AAZ33220.1 - 9.7e-36 122.5 0.0 1.4e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 LD-carboxypeptidase N-terminal domain Peptidase_S66C PF17676.1 AAZ33220.1 - 3.7e-30 105.0 0.1 5.4e-30 104.5 0.1 1.3 1 0 0 1 1 1 1 LD-carboxypeptidase C-terminal domain Radical_SAM PF04055.21 AAZ33221.1 - 4.9e-12 46.6 0.3 1.2e-11 45.2 0.3 1.7 1 1 0 1 1 1 1 Radical SAM superfamily DUF2937 PF11157.8 AAZ33222.1 - 1.5e-58 197.1 0.3 1.7e-58 196.9 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2937) TetR PF13972.6 AAZ33222.1 - 0.07 12.8 0.1 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 Bacterial transcriptional repressor Transposase_mut PF00872.18 AAZ33223.1 - 1.5e-115 386.2 0.0 1.8e-115 385.8 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ33223.1 - 7.6e-05 23.0 0.0 0.00021 21.6 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain DUF1835 PF08874.10 AAZ33224.1 - 1.1e-15 57.9 0.0 1.8e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1835) Thioredoxin_4 PF13462.6 AAZ33225.1 - 8.9e-20 71.5 0.0 2e-19 70.4 0.0 1.5 1 1 1 2 2 2 1 Thioredoxin DSBA PF01323.20 AAZ33225.1 - 3.8e-08 33.3 0.1 6.4e-06 26.1 0.1 2.3 2 0 0 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 AAZ33225.1 - 0.045 14.2 0.2 0.46 11.0 0.2 2.2 1 1 0 1 1 1 0 Thioredoxin-like domain Acetyltransf_5 PF13444.6 AAZ33226.1 - 3.2e-26 92.0 0.0 5.8e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Autoind_synth PF00765.17 AAZ33226.1 - 0.069 12.7 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Autoinducer synthase DUF3999 PF13163.6 AAZ33227.1 - 2.7e-143 478.3 7.0 3.1e-143 478.1 7.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3999) F5_F8_type_C PF00754.25 AAZ33227.1 - 0.042 14.0 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 F5/8 type C domain GntP_permease PF02447.16 AAZ33228.1 - 8e-179 594.9 45.4 9.3e-179 594.7 45.4 1.0 1 0 0 1 1 1 1 GntP family permease CitMHS PF03600.16 AAZ33228.1 - 1.1e-23 83.9 44.5 1.1e-23 83.9 44.5 1.5 1 1 0 1 1 1 1 Citrate transporter Na_H_antiport_2 PF13726.6 AAZ33228.1 - 0.0001 22.4 3.8 0.0001 22.4 3.8 3.5 3 0 0 3 3 3 2 Na+-H+ antiporter family DUF3007 PF11460.8 AAZ33228.1 - 2.8 8.3 5.5 1 9.6 1.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) DUF1285 PF06938.11 AAZ33229.1 - 2.1e-60 203.0 0.0 2.4e-60 202.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1285) AP_endonuc_2 PF01261.24 AAZ33230.1 - 6.9e-30 104.1 0.1 8.8e-30 103.7 0.1 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Bac_transf PF02397.16 AAZ33231.1 - 7.5e-68 227.8 0.0 1.4e-67 226.9 0.0 1.5 1 0 0 1 1 1 1 Bacterial sugar transferase CoA_binding_3 PF13727.6 AAZ33231.1 - 4.1e-27 95.3 0.2 6.9e-27 94.6 0.2 1.4 1 0 0 1 1 1 1 CoA-binding domain TssN PF17555.2 AAZ33231.1 - 0.21 10.9 6.9 1.2 8.5 8.2 1.5 2 0 0 2 2 2 0 Type VI secretion system, TssN DUF3021 PF11457.8 AAZ33231.1 - 0.3 11.4 5.2 0.59 10.5 5.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) SLT PF01464.20 AAZ33232.1 - 3.9e-30 103.9 0.0 7.2e-30 103.1 0.0 1.4 1 0 0 1 1 1 1 Transglycosylase SLT domain SLT_L PF14718.6 AAZ33232.1 - 7.9e-19 67.6 0.2 7.9e-19 67.6 0.2 3.8 3 0 0 3 3 3 1 Soluble lytic murein transglycosylase L domain Cucumo_coat PF00760.18 AAZ33232.1 - 6.8e-07 29.1 0.0 1.4e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Cucumovirus coat protein TPR_4 PF07721.14 AAZ33232.1 - 0.64 10.8 5.1 0.75 10.6 1.6 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat MNHE PF01899.16 AAZ33233.1 - 1.1e-35 122.6 2.6 1.2e-35 122.4 2.6 1.0 1 0 0 1 1 1 1 Na+/H+ ion antiporter subunit Flagellin_N PF00669.20 AAZ33234.1 - 1e-19 71.0 12.2 1e-19 71.0 12.2 2.8 2 0 0 2 2 2 1 Bacterial flagellin N-terminal helical region Flagellin_C PF00700.21 AAZ33234.1 - 7.6 7.0 17.7 1.9 8.9 3.9 2.9 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region Flavin_Reduct PF01613.18 AAZ33235.1 - 8.5e-26 90.8 0.1 1.1e-25 90.5 0.1 1.1 1 0 0 1 1 1 1 Flavin reductase like domain MqsA_antitoxin PF15731.5 AAZ33235.1 - 0.086 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA CABIT PF12736.7 AAZ33235.1 - 0.096 12.0 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Cell-cycle sustaining, positive selection, Abhydrolase_6 PF12697.7 AAZ33236.1 - 6.9e-20 72.6 1.9 8.1e-20 72.4 1.9 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AAZ33236.1 - 9.6e-17 61.5 0.8 7.1e-11 42.2 0.6 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AAZ33236.1 - 3.1e-11 43.0 0.7 7.6e-11 41.7 0.7 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 AAZ33236.1 - 0.00049 20.0 0.1 0.71 9.7 0.0 3.0 2 1 1 3 3 3 2 Serine hydrolase Abhydrolase_4 PF08386.10 AAZ33236.1 - 0.0038 17.3 0.0 0.0057 16.7 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_2 PF02230.16 AAZ33236.1 - 0.015 15.1 1.6 0.82 9.4 0.1 2.7 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase PhoPQ_related PF10142.9 AAZ33236.1 - 0.16 10.6 0.0 0.2 10.3 0.0 1.1 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein SMC_N PF02463.19 AAZ33237.1 - 9.5e-68 227.9 0.0 2.5e-67 226.6 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AAZ33237.1 - 6.2e-20 72.6 0.3 6.2e-20 72.6 0.3 7.1 2 2 2 4 4 4 1 AAA domain AAA_21 PF13304.6 AAZ33237.1 - 1.5e-13 51.3 3.0 6.6e-07 29.4 0.2 3.4 3 2 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AAZ33237.1 - 2e-12 47.5 0.0 2e-08 34.4 0.0 3.1 2 2 0 2 2 2 2 AAA ATPase domain SMC_hinge PF06470.13 AAZ33237.1 - 1.5e-07 31.7 1.4 1.7e-06 28.4 0.2 3.1 2 1 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_29 PF13555.6 AAZ33237.1 - 7.4e-05 22.4 0.0 0.00016 21.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain LpxC PF03331.13 AAZ33238.1 - 4.8e-108 360.7 0.0 5.5e-108 360.5 0.0 1.0 1 0 0 1 1 1 1 UDP-3-O-acyl N-acetylglycosamine deacetylase CM_2 PF01817.21 AAZ33239.1 - 1.2e-15 57.6 0.4 1.4e-15 57.4 0.4 1.1 1 0 0 1 1 1 1 Chorismate mutase type II HTH_AsnC-type PF13404.6 AAZ33239.1 - 0.017 15.0 0.6 0.031 14.1 0.6 1.5 1 1 0 1 1 1 0 AsnC-type helix-turn-helix domain Prefoldin_3 PF13758.6 AAZ33239.1 - 0.051 13.6 0.0 0.087 12.9 0.0 1.5 1 0 0 1 1 1 0 Prefoldin subunit Acetyltransf_1 PF00583.25 AAZ33240.1 - 3.5e-16 59.5 0.0 4.4e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AAZ33240.1 - 2.1e-13 50.3 0.0 2.8e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AAZ33240.1 - 4e-13 50.2 0.1 4.7e-13 50.0 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAZ33240.1 - 1.3e-11 44.7 0.0 1.9e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AAZ33240.1 - 3.4e-08 33.8 0.0 4.2e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 AAZ33240.1 - 0.0088 15.7 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAZ33240.1 - 0.014 15.4 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.6 AAZ33240.1 - 0.026 14.7 0.0 0.045 13.9 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF2269 PF10027.9 AAZ33241.1 - 1.7e-20 73.6 18.0 7.1e-20 71.6 18.0 1.7 1 1 0 1 1 1 1 Predicted integral membrane protein (DUF2269) DUF2796 PF10986.8 AAZ33242.1 - 3.5e-51 173.5 0.5 3.5e-51 173.5 0.5 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2796) FecR PF04773.13 AAZ33243.1 - 8e-17 61.7 0.3 1.6e-16 60.7 0.3 1.5 1 0 0 1 1 1 1 FecR protein DUF4880 PF16220.5 AAZ33243.1 - 8.5e-11 41.6 4.8 8.5e-11 41.6 4.8 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4880) DUF4974 PF16344.5 AAZ33243.1 - 0.00016 21.6 0.0 0.00026 20.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4974) DUF2059 PF09832.9 AAZ33245.1 - 8.4e-13 48.2 0.8 5.1e-07 29.7 0.1 2.7 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2059) AIRS_C PF02769.22 AAZ33245.1 - 0.027 14.6 0.0 0.038 14.1 0.0 1.3 1 0 0 1 1 1 0 AIR synthase related protein, C-terminal domain Glyco_trans_1_4 PF13692.6 AAZ33246.1 - 1.2e-24 87.3 0.0 2.1e-24 86.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AAZ33246.1 - 2e-23 82.8 0.0 3.5e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 AAZ33246.1 - 1.9e-14 54.4 3.3 3.9e-14 53.4 3.3 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 AAZ33246.1 - 1.1e-12 48.3 0.6 3e-12 46.9 0.6 1.7 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 AAZ33246.1 - 0.0013 19.0 0.0 0.003 17.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 AAZ33246.1 - 0.092 12.8 0.0 0.27 11.2 0.0 1.7 1 1 0 1 1 1 0 Glycosyl transferase 4-like Aldolase_II PF00596.21 AAZ33247.1 - 2.4e-44 151.5 0.0 2.8e-44 151.3 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain MCPsignal PF00015.21 AAZ33248.1 - 3.4e-34 118.1 29.0 5.2e-34 117.5 13.6 2.5 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AAZ33248.1 - 0.00019 21.7 0.6 0.0032 17.8 0.0 3.3 3 1 0 3 3 2 1 HAMP domain Syntaxin PF00804.25 AAZ33248.1 - 0.0065 16.2 9.2 0.013 15.2 1.0 3.4 2 1 2 4 4 4 1 Syntaxin BLOC1_2 PF10046.9 AAZ33248.1 - 0.0085 16.4 4.7 0.74 10.1 0.0 4.1 2 2 2 4 4 4 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.11 AAZ33248.1 - 0.012 15.8 14.8 5.3 7.4 1.7 5.1 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 AAZ33248.1 - 0.022 14.8 10.3 5.1 7.1 1.8 3.8 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) Mod_r PF07200.13 AAZ33248.1 - 0.042 14.0 5.3 0.26 11.4 0.1 3.2 2 2 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF3149 PF11346.8 AAZ33248.1 - 0.043 13.4 4.0 0.07 12.8 1.7 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3149) GCN5L1 PF06320.13 AAZ33248.1 - 0.052 13.7 1.7 6.1 7.0 0.1 3.0 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) Arv1 PF04161.13 AAZ33248.1 - 0.087 13.0 1.9 0.2 11.8 1.9 1.5 1 0 0 1 1 1 0 Arv1-like family Sec34 PF04136.15 AAZ33248.1 - 0.21 11.5 10.9 9.9 6.0 0.2 4.4 2 2 3 6 6 6 0 Sec34-like family Vps51 PF08700.11 AAZ33248.1 - 0.24 11.5 2.5 1.9 8.6 0.2 3.3 3 0 0 3 3 3 0 Vps51/Vps67 Laminin_II PF06009.12 AAZ33248.1 - 0.26 11.3 15.9 0.53 10.3 3.9 3.6 2 2 2 4 4 4 0 Laminin Domain II Tweety PF04906.13 AAZ33248.1 - 0.3 9.7 5.4 0.19 10.4 0.7 2.4 2 0 0 2 2 2 0 Tweety IFT57 PF10498.9 AAZ33248.1 - 0.77 8.7 8.4 0.092 11.7 2.3 2.2 2 1 0 2 2 2 0 Intra-flagellar transport protein 57 Phasin_2 PF09361.10 AAZ33248.1 - 1.4 9.2 16.5 2 8.7 2.5 4.0 3 1 1 4 4 4 0 Phasin protein WXG100 PF06013.12 AAZ33248.1 - 1.4 9.2 12.5 1.1 9.5 2.0 4.7 3 1 2 5 5 5 0 Proteins of 100 residues with WXG dCache_1 PF02743.18 AAZ33248.1 - 2 8.1 9.2 1.3 8.8 1.7 2.5 2 0 0 2 2 2 0 Cache domain AIP3 PF03915.13 AAZ33248.1 - 2.7 7.0 10.0 6.4 5.8 10.1 1.5 1 1 0 1 1 1 0 Actin interacting protein 3 T7SS_ESX_EspC PF10824.8 AAZ33248.1 - 3.1 8.3 16.5 0.74 10.3 2.7 3.8 2 2 2 4 4 4 0 Excreted virulence factor EspC, type VII ESX diderm DUF148 PF02520.17 AAZ33248.1 - 3.4 7.8 12.2 1.3 9.1 1.2 3.4 3 1 0 3 3 3 0 Domain of unknown function DUF148 BORCS6 PF10157.9 AAZ33248.1 - 4.5 7.5 10.6 3.1 8.0 1.5 3.3 1 1 1 3 3 3 0 BLOC-1-related complex sub-unit 6 PIN_8 PF18476.1 AAZ33248.1 - 4.7 7.0 6.0 13 5.5 1.2 2.4 2 1 1 3 3 3 0 PIN like domain Shikimate_dh_N PF08501.11 AAZ33249.1 - 4.2e-22 78.2 0.0 8.1e-22 77.3 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 AAZ33249.1 - 3.1e-11 42.8 0.4 6.7e-11 41.8 0.4 1.6 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 AAZ33249.1 - 1.6e-10 41.2 0.0 2.6e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 AAZ33249.1 - 0.047 13.9 0.0 0.085 13.1 0.0 1.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 AAZ33249.1 - 0.18 12.4 0.0 0.36 11.5 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent F_bP_aldolase PF01116.20 AAZ33250.1 - 5.5e-93 311.5 0.0 6.6e-93 311.2 0.0 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II OST_P2 PF18235.1 AAZ33250.1 - 0.022 14.7 0.0 0.047 13.6 0.0 1.5 2 0 0 2 2 2 0 Oligosaccharyltransferase Peripheral 2 domain DUF285 PF03382.14 AAZ33250.1 - 0.071 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Mycoplasma protein of unknown function, DUF285 GST_N PF02798.20 AAZ33252.1 - 2.2e-16 59.9 0.0 2.4e-15 56.6 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 AAZ33252.1 - 1.1e-14 54.6 0.0 2.2e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AAZ33252.1 - 3.1e-12 46.6 0.0 5.4e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 AAZ33252.1 - 8.5e-10 38.5 0.1 1.6e-09 37.6 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 AAZ33252.1 - 1.5e-09 37.9 0.0 2.2e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 AAZ33252.1 - 2.2e-06 27.8 0.0 3.5e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 AAZ33252.1 - 0.0051 17.5 0.0 0.023 15.4 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 AAZ33252.1 - 0.034 14.0 0.0 0.07 12.9 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_5 PF18485.1 AAZ33252.1 - 0.046 14.1 0.0 0.092 13.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 AAZ33253.1 - 3e-17 62.7 0.0 4.9e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 AAZ33253.1 - 5.3e-13 49.2 0.0 1e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AAZ33253.1 - 1.1e-09 38.4 0.0 1.9e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 AAZ33253.1 - 1.1e-06 28.8 0.0 1.6e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 AAZ33253.1 - 7.2e-06 26.1 0.0 1.2e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 AAZ33253.1 - 5.2e-05 23.2 0.0 0.00014 21.8 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ni_hydr_CYTB PF01292.20 AAZ33254.1 - 5.5e-21 75.0 13.1 1.2e-20 73.9 13.1 1.5 1 1 0 1 1 1 1 Prokaryotic cytochrome b561 Cytochrom_B561 PF03188.16 AAZ33254.1 - 0.068 13.3 8.8 0.37 10.9 0.9 2.2 1 1 1 2 2 2 0 Eukaryotic cytochrome b561 DUF1206 PF06724.11 AAZ33254.1 - 0.098 12.7 6.3 1.5 9.0 0.4 2.6 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1206) DUF4405 PF14358.6 AAZ33254.1 - 2 9.0 14.2 0.19 12.3 4.6 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4405) Med26 PF08711.11 AAZ33255.1 - 4.7e-09 36.1 0.0 21 5.2 0.0 11.0 12 2 2 14 14 14 2 TFIIS helical bundle-like domain TPR_16 PF13432.6 AAZ33255.1 - 1.6e-05 25.5 80.8 9.6 7.0 1.0 18.3 10 6 8 19 19 19 8 Tetratricopeptide repeat DUF2944 PF11161.8 AAZ33255.1 - 8.1e-05 22.6 54.6 13 5.6 0.0 17.6 21 0 0 21 21 21 4 Protein of unknown function (DUF2946) FOXP-CC PF16159.5 AAZ33255.1 - 0.087 13.5 29.8 17 6.1 0.0 14.6 19 1 1 20 20 20 0 FOXP coiled-coil domain DUF1400 PF07176.11 AAZ33255.1 - 0.25 11.7 9.6 37 4.6 0.0 6.5 5 2 2 7 7 7 0 Alpha/beta hydrolase of unknown function (DUF1400) Peptidase_M90 PF06167.12 AAZ33256.1 - 7.4e-91 304.1 0.0 8.5e-91 303.9 0.0 1.0 1 0 0 1 1 1 1 Glucose-regulated metallo-peptidase M90 UTRA PF07702.13 AAZ33257.1 - 5.1e-37 126.9 0.2 7.7e-37 126.3 0.2 1.3 1 0 0 1 1 1 1 UTRA domain GntR PF00392.21 AAZ33257.1 - 4e-18 64.8 0.0 8.3e-18 63.8 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_41 PF14502.6 AAZ33257.1 - 0.00016 21.3 0.0 0.00031 20.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma54_activat PF00158.26 AAZ33258.1 - 1e-66 223.8 0.3 2.1e-66 222.8 0.0 1.6 2 0 0 2 2 2 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AAZ33258.1 - 2.4e-19 69.8 0.0 6.8e-19 68.4 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 AAZ33258.1 - 2.3e-10 40.1 2.4 3.6e-10 39.5 0.2 2.5 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 AAZ33258.1 - 2.2e-06 27.7 0.0 5.8e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 AAZ33258.1 - 0.00085 18.8 0.0 0.073 12.4 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA PF00004.29 AAZ33258.1 - 0.00088 19.7 0.0 0.0021 18.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 AAZ33258.1 - 0.004 17.3 0.1 0.012 15.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) PAS_8 PF13188.7 AAZ33258.1 - 0.0047 16.9 0.0 0.014 15.4 0.0 1.9 1 0 0 1 1 1 1 PAS domain MCM PF00493.23 AAZ33258.1 - 0.0055 15.8 0.0 0.018 14.2 0.0 1.8 1 1 0 1 1 1 1 MCM P-loop domain HTH_50 PF18024.1 AAZ33258.1 - 0.0077 15.8 0.1 0.018 14.6 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain PAS_7 PF12860.7 AAZ33258.1 - 0.028 14.6 0.0 0.065 13.4 0.0 1.7 1 0 0 1 1 1 0 PAS fold AAA_16 PF13191.6 AAZ33258.1 - 0.04 14.3 0.5 0.14 12.6 0.1 2.2 2 1 0 2 2 2 0 AAA ATPase domain IclR PF01614.18 AAZ33258.1 - 0.07 13.0 0.0 0.38 10.6 0.0 2.1 2 0 0 2 2 2 0 Bacterial transcriptional regulator AAA_30 PF13604.6 AAZ33258.1 - 0.084 12.6 0.7 1.5 8.5 0.0 3.0 3 1 0 3 3 3 0 AAA domain ATPase PF06745.13 AAZ33258.1 - 0.12 11.7 0.0 0.42 9.9 0.0 1.8 2 0 0 2 2 2 0 KaiC Cons_hypoth95 PF03602.15 AAZ33258.1 - 0.12 12.0 0.1 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Hexapep PF00132.24 AAZ33259.1 - 4.2e-16 57.9 6.7 2.1e-05 24.1 2.0 4.1 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AAZ33259.1 - 2.9e-05 23.7 7.2 0.0052 16.5 0.3 3.8 3 1 1 4 4 4 2 Hexapeptide repeat of succinyl-transferase BPD_transp_1 PF00528.22 AAZ33260.1 - 2.5e-09 37.2 30.2 9.8e-09 35.2 26.0 2.8 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Extensin-like_C PF06904.12 AAZ33261.1 - 6.8e-62 208.6 0.0 8e-62 208.4 0.0 1.0 1 0 0 1 1 1 1 Extensin-like protein C-terminus PAS_4 PF08448.10 AAZ33263.1 - 1.1e-07 32.0 0.0 3.2e-07 30.6 0.0 1.7 1 1 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AAZ33263.1 - 2e-05 24.8 0.1 3.7e-05 23.9 0.0 1.5 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 AAZ33263.1 - 0.001 19.1 0.0 0.0017 18.3 0.0 1.5 1 1 0 1 1 1 1 PAS fold PAS_8 PF13188.7 AAZ33263.1 - 0.13 12.3 0.6 6.3 6.9 0.1 2.3 2 1 0 2 2 2 0 PAS domain PAS_7 PF12860.7 AAZ33263.1 - 0.13 12.4 0.3 0.36 11.0 0.1 1.7 2 0 0 2 2 2 0 PAS fold FecR PF04773.13 AAZ33264.1 - 1.1e-18 67.6 0.2 1.9e-18 66.9 0.2 1.3 1 0 0 1 1 1 1 FecR protein DUF4880 PF16220.5 AAZ33264.1 - 1.9e-13 50.1 7.3 4.7e-13 48.8 7.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4880) DUF2484 PF10658.9 AAZ33264.1 - 0.011 16.0 0.2 0.021 15.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2484) RskA PF10099.9 AAZ33264.1 - 0.016 15.5 0.5 0.023 15.0 0.5 1.4 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF4974 PF16344.5 AAZ33264.1 - 0.019 14.9 0.0 0.032 14.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4974) HGWP PF03578.15 AAZ33264.1 - 1.3 8.5 3.8 2.9 7.5 3.8 1.5 1 0 0 1 1 1 0 HGWP repeat CxxCxxCC PF03692.15 AAZ33265.1 - 8.7e-10 39.2 2.3 1.2e-09 38.7 2.3 1.3 1 0 0 1 1 1 1 Putative zinc- or iron-chelating domain MdoG PF04349.12 AAZ33266.1 - 1e-178 595.2 0.0 1.2e-178 595.0 0.0 1.0 1 0 0 1 1 1 1 Periplasmic glucan biosynthesis protein, MdoG TAT_signal PF10518.9 AAZ33266.1 - 0.0084 15.9 0.7 0.0084 15.9 0.7 1.8 2 0 0 2 2 2 1 TAT (twin-arginine translocation) pathway signal sequence SBP_bac_5 PF00496.22 AAZ33267.1 - 1.1e-71 241.8 0.0 1.4e-71 241.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle AAA_18 PF13238.6 AAZ33268.1 - 5.6e-07 30.2 0.1 1.2e-06 29.1 0.1 1.6 1 1 0 1 1 1 1 AAA domain Guanylate_kin PF00625.21 AAZ33268.1 - 1.5e-05 24.8 0.0 1.9e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 AAZ33268.1 - 0.00024 21.5 1.4 0.00075 19.9 1.4 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AAZ33268.1 - 0.0011 18.6 0.0 0.0024 17.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.6 AAZ33268.1 - 0.0012 19.0 2.5 1.7 8.8 0.0 3.1 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.6 AAZ33268.1 - 0.0092 15.7 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 AAZ33268.1 - 0.017 15.4 0.1 0.055 13.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 AAZ33268.1 - 0.017 14.6 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Ploopntkinase3 PF18751.1 AAZ33268.1 - 0.032 14.1 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_22 PF13401.6 AAZ33268.1 - 0.059 13.6 0.0 0.15 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 AAZ33268.1 - 0.07 13.6 0.0 0.11 13.1 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_PrkA PF08298.11 AAZ33268.1 - 0.15 10.9 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain P-II PF00543.22 AAZ33270.1 - 3.5e-43 146.3 2.5 4e-43 146.2 2.5 1.0 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II DUF3240 PF11582.8 AAZ33270.1 - 0.0035 17.5 0.0 0.0045 17.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3240) Cdc6_C PF09079.11 AAZ33270.1 - 0.031 14.3 0.0 0.057 13.4 0.0 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain Nit_Regul_Hom PF10126.9 AAZ33270.1 - 0.05 13.6 0.0 5.7 7.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein, homolog of nitrogen regulatory protein PII DUF2344 PF10105.9 AAZ33270.1 - 0.1 12.4 0.0 0.14 12.0 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) CdAMP_rec PF06153.11 AAZ33270.1 - 0.15 12.3 1.4 4.5 7.5 1.4 2.6 1 1 0 1 1 1 0 Cyclic-di-AMP receptor DEAD PF00270.29 AAZ33271.1 - 1.4e-19 70.5 0.0 3.8e-19 69.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AAZ33271.1 - 7.9e-19 68.0 0.0 2.2e-16 60.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecG_wedge PF17191.4 AAZ33271.1 - 3.6e-17 62.5 0.0 5.7e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 RecG wedge domain ResIII PF04851.15 AAZ33271.1 - 7.9e-10 39.0 0.0 1.5e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 AAZ33271.1 - 2.1e-05 24.3 0.2 5.8e-05 22.9 0.2 1.7 1 0 0 1 1 1 1 AAA domain SNF2_N PF00176.23 AAZ33271.1 - 0.00029 19.7 0.0 0.00038 19.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF2075 PF09848.9 AAZ33271.1 - 0.012 14.9 0.0 0.024 13.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 AAZ33271.1 - 0.033 14.5 0.7 0.82 9.9 0.1 3.4 3 2 1 4 4 4 0 AAA domain SecA_DEAD PF07517.14 AAZ33271.1 - 0.039 13.2 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 SecA DEAD-like domain AAA_16 PF13191.6 AAZ33271.1 - 0.047 14.1 0.9 0.8 10.1 0.0 2.9 2 1 0 2 2 2 0 AAA ATPase domain HHH_5 PF14520.6 AAZ33271.1 - 0.058 14.0 0.0 0.21 12.2 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain Cdd1 PF11731.8 AAZ33271.1 - 0.07 13.4 0.0 0.35 11.1 0.0 2.1 2 0 0 2 2 2 0 Pathogenicity locus DNA_pol_lambd_f PF10391.9 AAZ33271.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda APH PF01636.23 AAZ33272.1 - 2.4e-36 125.9 1.0 3.5e-36 125.4 1.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 AAZ33272.1 - 0.00027 20.4 0.1 0.00047 19.6 0.1 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase DUF2252 PF10009.9 AAZ33272.1 - 0.17 10.9 0.2 0.47 9.5 0.2 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2252) ExbD PF02472.16 AAZ33274.1 - 9.7e-26 90.5 0.1 1.1e-25 90.3 0.1 1.0 1 0 0 1 1 1 1 Biopolymer transport protein ExbD/TolR Adenine_glyco PF03352.13 AAZ33275.1 - 1.7e-18 67.0 0.0 2.4e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Methyladenine glycosylase zf-C2H2_6 PF13912.6 AAZ33275.1 - 0.19 11.8 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger Autoind_synth PF00765.17 AAZ33276.1 - 2.8e-43 147.6 0.0 4.1e-43 147.0 0.0 1.2 1 0 0 1 1 1 1 Autoinducer synthase RHH_1 PF01402.21 AAZ33277.1 - 7e-06 25.8 0.4 1.2e-05 25.0 0.4 1.4 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family UPF0054 PF02130.17 AAZ33278.1 - 9.9e-38 128.8 0.0 1.1e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 FixH PF05751.11 AAZ33279.1 - 4.9e-37 127.2 0.0 5.7e-37 127.0 0.0 1.0 1 0 0 1 1 1 1 FixH FtsK_SpoIIIE PF01580.18 AAZ33281.1 - 0.021 14.2 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_25 PF13481.6 AAZ33281.1 - 0.052 13.1 0.2 0.11 12.0 0.2 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 AAZ33281.1 - 0.13 12.3 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain Lyase_1 PF00206.20 AAZ33282.1 - 2.9e-92 309.4 1.7 3.9e-92 309.0 1.7 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 AAZ33282.1 - 5.2e-20 71.6 0.2 1.5e-19 70.1 0.2 1.9 1 0 0 1 1 1 1 Fumarase C C-terminus SUKH_5 PF14567.6 AAZ33283.1 - 6.7e-46 155.5 0.2 7.4e-46 155.3 0.2 1.0 1 0 0 1 1 1 1 SMI1-KNR4 cell-wall SMI1_KNR4 PF09346.10 AAZ33283.1 - 2.2e-07 31.3 0.3 1.9e-06 28.3 0.3 2.0 1 1 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SUKH_6 PF14568.6 AAZ33283.1 - 9.8e-06 26.0 0.2 3.3e-05 24.3 0.2 1.7 1 1 0 1 1 1 1 SMI1-KNR4 cell-wall Pan_kinase PF03309.14 AAZ33284.1 - 1.6e-41 142.5 0.0 2e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 Type III pantothenate kinase DUF748 PF05359.11 AAZ33285.1 - 2.6e-109 362.1 12.8 2.8e-40 138.0 0.1 4.5 5 0 0 5 5 5 3 Domain of Unknown Function (DUF748) AsmA PF05170.14 AAZ33285.1 - 1.5e-11 43.9 2.1 0.00013 20.9 0.1 3.4 3 0 0 3 3 3 3 AsmA family OmpA PF00691.20 AAZ33285.1 - 1.9e-07 31.3 0.0 0.00018 21.8 0.0 2.6 2 0 0 2 2 2 2 OmpA family Ribonuc_L-PSP PF01042.21 AAZ33286.1 - 2e-29 102.0 0.0 2.4e-29 101.8 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Eclosion PF04736.12 AAZ33286.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Eclosion hormone FliMN_C PF01052.20 AAZ33287.1 - 1.2e-24 86.1 1.9 2.6e-16 59.4 0.1 2.4 2 0 0 2 2 2 2 Type III flagellar switch regulator (C-ring) FliN C-term Kdo PF06293.14 AAZ33288.1 - 8.3e-54 182.1 0.0 1.1e-53 181.8 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 AAZ33288.1 - 0.0024 17.8 1.5 0.0038 17.2 1.5 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family HAD PF12710.7 AAZ33289.1 - 0.0066 16.9 0.0 0.033 14.6 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAZ33289.1 - 0.13 12.5 0.1 0.39 11.0 0.1 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase NolV PF06635.12 AAZ33290.1 - 1.7e-16 60.3 4.5 2.1e-16 59.9 4.5 1.1 1 0 0 1 1 1 1 Nodulation protein NolV FliH PF02108.16 AAZ33290.1 - 2.1e-09 37.5 0.1 2.9e-09 37.1 0.1 1.2 1 0 0 1 1 1 1 Flagellar assembly protein FliH SKI PF01202.22 AAZ33291.1 - 2.6e-54 183.6 0.0 3e-54 183.4 0.0 1.0 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 AAZ33291.1 - 5.5e-06 27.0 0.0 8.8e-06 26.3 0.0 1.3 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 AAZ33291.1 - 0.00036 20.4 0.1 0.0073 16.1 0.0 2.1 2 0 0 2 2 2 1 Cytidylate kinase Cytidylate_kin2 PF13189.6 AAZ33291.1 - 0.00065 19.9 0.1 0.036 14.2 0.0 2.1 1 1 0 2 2 2 1 Cytidylate kinase-like family AAA PF00004.29 AAZ33291.1 - 0.003 18.0 0.0 0.0052 17.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 AAZ33291.1 - 0.0089 16.2 0.0 0.018 15.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 AAZ33291.1 - 0.011 16.3 0.1 0.013 16.0 0.1 1.4 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 AAZ33291.1 - 0.018 15.4 0.3 0.036 14.5 0.3 1.8 1 1 0 1 1 1 0 AAA ATPase domain Rad17 PF03215.15 AAZ33291.1 - 0.018 15.0 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_5 PF07728.14 AAZ33291.1 - 0.04 13.9 0.0 0.07 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 AAZ33291.1 - 0.068 13.4 0.1 0.18 12.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 AAZ33291.1 - 0.068 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 AAZ33291.1 - 0.07 12.8 0.0 0.076 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain dNK PF01712.19 AAZ33291.1 - 0.086 12.7 0.0 0.31 10.9 0.0 1.8 2 0 0 2 2 2 0 Deoxynucleoside kinase APS_kinase PF01583.20 AAZ33291.1 - 0.11 12.4 0.1 0.66 9.9 0.0 2.0 1 1 0 2 2 2 0 Adenylylsulphate kinase RuvB_N PF05496.12 AAZ33291.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_29 PF13555.6 AAZ33291.1 - 0.14 11.9 0.1 0.24 11.2 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain Guanylate_kin PF00625.21 AAZ33291.1 - 0.16 11.7 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Guanylate kinase AAA_25 PF13481.6 AAZ33291.1 - 0.18 11.4 1.8 2.2 7.8 1.8 2.2 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 AAZ33291.1 - 0.28 11.6 0.0 0.43 11.0 0.0 1.3 1 0 0 1 1 1 0 RNA helicase LptE PF04390.12 AAZ33292.1 - 5e-08 33.6 1.2 5e-08 33.6 1.2 1.8 2 0 0 2 2 2 1 Lipopolysaccharide-assembly LPAM_2 PF13627.6 AAZ33292.1 - 3.7 7.5 5.1 6.3 6.8 5.1 1.4 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site T2SSF PF00482.23 AAZ33293.1 - 3.5e-15 56.0 3.9 3.5e-15 56.0 3.9 2.6 3 0 0 3 3 3 1 Type II secretion system (T2SS), protein F Ribosomal_L7Ae PF01248.26 AAZ33293.1 - 0.042 13.6 0.0 0.085 12.6 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SKG6 PF08693.10 AAZ33293.1 - 0.046 13.1 1.3 0.17 11.3 1.3 2.0 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Neurensin PF14927.6 AAZ33293.1 - 2.8 7.7 4.8 22 4.7 1.6 3.4 3 1 0 3 3 3 0 Neurensin Nramp PF01566.18 AAZ33294.1 - 5.4e-132 440.1 21.3 6.4e-132 439.9 21.3 1.0 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Metallophos PF00149.28 AAZ33295.1 - 1e-11 45.7 0.1 1.7e-11 45.0 0.1 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AAZ33295.1 - 6.4e-07 29.7 0.0 1.1e-06 29.0 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 AAZ33296.1 - 2.6e-09 37.9 0.1 4.6e-09 37.1 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ABC_tran PF00005.27 AAZ33297.1 - 5.8e-28 98.1 0.0 7.2e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAZ33297.1 - 2.1e-07 31.1 0.9 0.0056 16.5 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 AAZ33297.1 - 0.003 17.3 0.3 0.3 10.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 AAZ33297.1 - 0.0033 17.1 0.0 0.0065 16.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 AAZ33297.1 - 0.019 14.5 0.4 2 8.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 AAZ33297.1 - 0.025 14.7 0.0 0.058 13.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 AAZ33297.1 - 0.039 14.3 4.9 0.14 12.6 4.9 1.9 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 AAZ33297.1 - 0.078 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 AAZ33297.1 - 0.081 13.2 0.6 0.75 10.1 0.1 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 AAZ33297.1 - 0.094 12.6 0.6 0.22 11.4 0.6 1.6 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 AAZ33297.1 - 0.27 11.3 0.8 0.45 10.5 0.5 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 AAZ33297.1 - 1.4 9.4 3.3 5.3 7.6 1.5 2.2 1 1 1 2 2 2 0 AAA domain TetR_C_30 PF17939.1 AAZ33298.1 - 1.4e-28 99.4 0.5 2.7e-28 98.5 0.5 1.5 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 AAZ33298.1 - 2.6e-14 52.7 1.9 3.7e-14 52.2 0.7 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family S-methyl_trans PF02574.16 AAZ33299.1 - 8.6e-55 186.4 0.0 9.7e-55 186.2 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase SecB PF02556.14 AAZ33300.1 - 9.8e-55 184.3 0.0 1.2e-54 184.1 0.0 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit SecB DUF2012 PF09430.10 AAZ33300.1 - 0.07 13.3 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) DUF4424 PF14415.6 AAZ33300.1 - 0.16 11.2 0.0 0.21 10.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4424) DUF4727 PF15856.5 AAZ33300.1 - 0.2 11.2 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4727) IstB_IS21 PF01695.17 AAZ33301.1 - 0.0065 16.2 1.4 0.0065 16.2 1.4 1.4 2 0 0 2 2 2 1 IstB-like ATP binding protein DUF2059 PF09832.9 AAZ33302.1 - 1.9e-21 75.9 0.4 1.9e-21 75.9 0.4 2.1 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2059) tRNA-synt_His PF13393.6 AAZ33302.1 - 0.045 13.0 0.9 0.12 11.7 0.6 1.7 2 0 0 2 2 2 0 Histidyl-tRNA synthetase ApoA-II PF04711.13 AAZ33302.1 - 0.092 12.9 3.6 0.11 12.7 0.3 2.1 2 0 0 2 2 2 0 Apolipoprotein A-II (ApoA-II) Ribosomal_L12 PF00542.19 AAZ33303.1 - 2.3e-27 95.1 9.2 4.4e-27 94.2 9.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 AAZ33303.1 - 4.4e-14 51.9 5.4 4.4e-14 51.9 5.4 2.7 2 1 1 3 3 3 1 Ribosomal protein L7/L12 dimerisation domain Lycopene_cycl PF05834.12 AAZ33303.1 - 0.064 12.3 0.4 0.069 12.2 0.4 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein EutC PF05985.11 AAZ33304.1 - 3.8e-95 317.6 0.4 4.3e-95 317.4 0.4 1.0 1 0 0 1 1 1 1 Ethanolamine ammonia-lyase light chain (EutC) PTS_2-RNA PF01885.16 AAZ33305.1 - 2.1e-42 145.2 0.0 2.5e-42 145.0 0.0 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family PARP PF00644.20 AAZ33305.1 - 0.0044 16.6 0.0 0.0064 16.1 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Paralemmin PF03285.15 AAZ33305.1 - 0.045 13.3 0.0 0.065 12.8 0.0 1.1 1 0 0 1 1 1 0 Paralemmin PDDEXK_7 PF04411.12 AAZ33305.1 - 0.049 13.6 0.0 0.069 13.1 0.0 1.2 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily UTRA PF07702.13 AAZ33307.1 - 8.3e-36 122.9 0.4 1.2e-35 122.4 0.4 1.3 1 0 0 1 1 1 1 UTRA domain GntR PF00392.21 AAZ33307.1 - 4.1e-19 68.0 0.1 1.3e-18 66.4 0.1 1.9 1 1 1 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_DeoR PF08220.12 AAZ33307.1 - 0.002 17.8 0.0 0.0047 16.6 0.0 1.6 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain MarR PF01047.22 AAZ33307.1 - 0.0054 16.6 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 AAZ33307.1 - 0.024 14.2 0.1 0.27 10.8 0.1 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 AAZ33307.1 - 0.033 14.2 0.0 0.069 13.1 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain MarR_2 PF12802.7 AAZ33307.1 - 0.11 12.5 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 MarR family RP-C PF03428.13 AAZ33307.1 - 0.11 12.1 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 Replication protein C N-terminal domain FKBP_C PF00254.28 AAZ33308.1 - 6.7e-21 74.4 0.0 1.3e-20 73.5 0.0 1.5 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Na_H_Exchanger PF00999.21 AAZ33309.1 - 9.3e-33 113.5 27.7 2.5e-30 105.5 27.7 2.0 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family DUF575 PF04746.12 AAZ33309.1 - 0.13 12.5 0.5 0.68 10.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF575) Flavodoxin_2 PF02525.17 AAZ33310.1 - 1.1e-33 116.7 1.2 1.8e-33 115.9 1.2 1.4 1 1 0 1 1 1 1 Flavodoxin-like fold Cation_efflux PF01545.21 AAZ33311.1 - 1.7e-39 135.6 12.2 2.2e-39 135.3 12.2 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 AAZ33311.1 - 2e-23 82.3 0.0 3e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DUF1737 PF08410.10 AAZ33311.1 - 0.075 12.9 2.1 11 6.0 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF1737) Oxidored_q2 PF00420.24 AAZ33311.1 - 3.2 7.4 9.4 0.37 10.4 3.7 2.5 2 2 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L TauE PF01925.19 AAZ33312.1 - 2.2e-46 158.4 37.7 2.6e-46 158.2 37.7 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE Adeno_E3 PF06040.11 AAZ33312.1 - 6.4 7.0 7.0 0.34 11.1 0.2 2.2 2 0 0 2 2 2 0 Adenovirus E3 protein TruB_N PF01509.18 AAZ33313.1 - 1.2e-56 191.2 0.0 1.6e-56 190.8 0.0 1.2 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 AAZ33313.1 - 1.1e-21 76.7 0.1 2.7e-21 75.4 0.0 1.7 2 0 0 2 2 2 1 tRNA pseudouridylate synthase B C-terminal domain TruB-C_2 PF09157.11 AAZ33313.1 - 2.8e-18 65.7 0.0 5.8e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 Pseudouridine synthase II TruB, C-terminal PUA_3 PF17785.1 AAZ33313.1 - 0.017 14.9 0.0 0.052 13.4 0.0 1.9 1 0 0 1 1 1 0 PUA-like domain AP_endonuc_2 PF01261.24 AAZ33314.1 - 9.7e-21 74.2 0.1 2e-20 73.1 0.0 1.4 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel dUTPase PF00692.19 AAZ33315.1 - 4.9e-39 133.0 0.0 5.5e-39 132.8 0.0 1.0 1 0 0 1 1 1 1 dUTPase FtsX PF02687.21 AAZ33316.1 - 6.6e-13 48.9 18.9 2e-12 47.4 4.5 4.6 4 1 0 4 4 4 2 FtsX-like permease family MacB_PCD PF12704.7 AAZ33316.1 - 7.4e-09 36.2 0.0 7.4e-09 36.2 0.0 2.5 4 0 0 4 4 4 1 MacB-like periplasmic core domain Molydop_binding PF01568.21 AAZ33316.1 - 0.15 12.1 0.0 3.7 7.6 0.0 2.3 2 0 0 2 2 2 0 Molydopterin dinucleotide binding domain MCPsignal PF00015.21 AAZ33317.1 - 2e-45 154.7 31.9 1.9e-40 138.5 20.6 2.5 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain PAS_3 PF08447.12 AAZ33317.1 - 4.4e-17 62.2 0.1 1.7e-16 60.3 0.1 2.0 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 AAZ33317.1 - 8.6e-11 41.8 0.0 3.9e-10 39.7 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 AAZ33317.1 - 4.8e-10 39.6 0.0 1.7e-09 37.9 0.0 1.9 2 0 0 2 2 1 1 PAS domain PAS_4 PF08448.10 AAZ33317.1 - 0.00015 22.0 3.4 0.012 15.9 0.0 3.7 3 1 0 3 3 3 1 PAS fold BLOC1_2 PF10046.9 AAZ33317.1 - 0.011 16.0 14.8 0.3 11.4 1.8 4.2 2 2 3 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PAS_8 PF13188.7 AAZ33317.1 - 0.018 15.1 0.0 0.1 12.7 0.0 2.3 2 0 0 2 2 2 0 PAS domain DUF948 PF06103.11 AAZ33317.1 - 0.029 14.6 17.8 0.3 11.4 1.8 4.5 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Golgin_A5 PF09787.9 AAZ33317.1 - 0.031 13.8 19.2 0.22 11.0 2.6 2.3 2 0 0 2 2 2 0 Golgin subfamily A member 5 HBM PF16591.5 AAZ33317.1 - 0.047 13.1 26.1 0.18 11.2 11.4 2.4 2 0 0 2 2 2 0 Helical bimodular sensor domain SLATT_6 PF18169.1 AAZ33317.1 - 0.39 10.3 0.0 0.39 10.3 0.0 2.2 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 6 Fib_alpha PF08702.10 AAZ33317.1 - 0.43 10.8 14.7 0.59 10.3 4.2 3.4 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family ISG65-75 PF11727.8 AAZ33317.1 - 0.72 9.0 13.8 1 8.5 2.1 2.4 2 1 0 2 2 2 0 Invariant surface glycoprotein Snf7 PF03357.21 AAZ33317.1 - 0.78 9.3 19.1 0.12 12.0 3.7 2.6 2 1 0 2 2 2 0 Snf7 GAT PF03127.14 AAZ33317.1 - 0.8 10.1 6.9 3.6 8.0 0.1 3.3 2 1 1 3 3 3 0 GAT domain MIEAP PF16026.5 AAZ33317.1 - 0.91 9.7 8.6 0.15 12.3 2.5 2.3 2 0 0 2 2 2 0 Mitochondria-eating protein ACP_PD PF04336.12 AAZ33317.1 - 1.8 9.0 4.3 3.8 8.0 0.2 3.5 2 1 1 3 3 3 0 Acyl carrier protein phosphodiesterase Vps5 PF09325.10 AAZ33317.1 - 2 7.9 14.8 11 5.5 0.1 3.7 1 1 2 4 4 4 0 Vps5 C terminal like DUF16 PF01519.16 AAZ33317.1 - 2.4 8.7 14.0 0.37 11.3 1.0 3.4 2 1 1 3 3 3 0 Protein of unknown function DUF16 DUF3130 PF11328.8 AAZ33317.1 - 2.9 8.2 7.8 4.6 7.6 0.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3130 ATG16 PF08614.11 AAZ33317.1 - 2.9 8.1 28.0 5.2 7.2 8.7 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) NPV_P10 PF05531.12 AAZ33317.1 - 4.9 7.7 13.5 22 5.6 0.1 4.6 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DASH_Duo1 PF08651.10 AAZ33317.1 - 5.9 6.7 13.0 0.74 9.6 0.9 4.1 4 0 0 4 4 4 0 DASH complex subunit Duo1 Glycos_transf_2 PF00535.26 AAZ33318.1 - 2.4e-12 47.0 0.0 3.5e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAZ33318.1 - 2.7e-06 27.4 0.0 5.8e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 HemolysinCabind PF00353.19 AAZ33320.1 - 5.6e-15 55.0 41.2 4.7e-09 36.1 10.4 4.7 3 1 1 4 4 4 3 RTX calcium-binding nonapeptide repeat (4 copies) Peptidase_M10_C PF08548.11 AAZ33320.1 - 6.4e-14 52.3 21.7 7.8e-11 42.2 9.4 3.3 1 1 0 2 2 2 2 Peptidase M10 serralysin C terminal Peptidase_M10 PF00413.24 AAZ33320.1 - 1.2e-07 31.7 0.4 1.2e-06 28.4 0.4 2.3 1 1 0 1 1 1 1 Matrixin Reprolysin_4 PF13583.6 AAZ33320.1 - 1.5e-06 28.0 0.0 3e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 AAZ33320.1 - 2.7e-06 26.8 0.1 4.9e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Met-zincin Reprolysin_5 PF13688.6 AAZ33320.1 - 0.00011 22.4 0.0 0.00021 21.5 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 AAZ33320.1 - 0.0037 17.8 0.0 0.01 16.3 0.0 1.9 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 AAZ33320.1 - 0.0059 15.6 0.1 0.011 14.7 0.1 1.4 1 0 0 1 1 1 1 Peptidase M66 Peptidase_M43 PF05572.13 AAZ33320.1 - 0.043 13.7 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Peptidase_M11 PF05548.11 AAZ33320.1 - 0.078 12.1 0.2 0.21 10.7 0.0 1.7 2 0 0 2 2 2 0 Gametolysin peptidase M11 Reprolysin_2 PF13574.6 AAZ33320.1 - 0.097 12.6 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Phage_holin_3_6 PF07332.11 AAZ33321.1 - 1e-18 67.4 4.8 1.1e-18 67.3 4.8 1.0 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III TMEM43 PF07787.12 AAZ33321.1 - 0.35 10.2 1.1 0.4 10.0 1.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 43 Na_H_Exchanger PF00999.21 AAZ33322.1 - 7.2e-67 225.8 40.0 8.3e-67 225.6 40.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF412 PF04217.13 AAZ33322.1 - 4.1 7.3 5.6 14 5.6 1.0 2.8 2 0 0 2 2 2 0 Protein of unknown function, DUF412 MR_MLE_C PF13378.6 AAZ33323.1 - 2.6e-47 161.2 0.0 3.4e-47 160.8 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 AAZ33323.1 - 9.3e-12 45.2 0.0 2.6e-11 43.7 0.0 1.7 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain SmpA_OmlA PF04355.13 AAZ33324.1 - 3.7e-06 26.6 0.1 6.8e-06 25.8 0.1 1.4 1 0 0 1 1 1 1 SmpA / OmlA family DUF4124 PF13511.6 AAZ33324.1 - 0.00037 20.8 0.6 0.0013 19.0 0.6 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4124) cNMP_binding PF00027.29 AAZ33325.1 - 3.9e-13 49.3 0.0 1.6e-12 47.3 0.0 2.0 2 1 1 3 3 3 1 Cyclic nucleotide-binding domain HTH_Crp_2 PF13545.6 AAZ33325.1 - 0.0014 18.5 1.3 0.0021 18.0 0.3 1.9 2 1 0 2 2 2 1 Crp-like helix-turn-helix domain CsrA PF02599.16 AAZ33326.1 - 3.2e-27 94.2 1.4 3.6e-27 94.1 1.4 1.0 1 0 0 1 1 1 1 Global regulator protein family S1 PF00575.23 AAZ33326.1 - 0.053 13.9 0.2 2.5 8.5 0.1 2.0 1 1 1 2 2 2 0 S1 RNA binding domain GerE PF00196.19 AAZ33326.1 - 0.064 12.8 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family Aldolase_II PF00596.21 AAZ33327.1 - 0.057 13.4 0.0 0.2 11.6 0.0 1.8 2 0 0 2 2 2 0 Class II Aldolase and Adducin N-terminal domain Oxidored_FMN PF00724.20 AAZ33328.1 - 2.7e-77 260.4 0.0 3.3e-77 260.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family PsaL PF02605.15 AAZ33328.1 - 0.15 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Photosystem I reaction centre subunit XI Dus PF01207.17 AAZ33328.1 - 0.2 10.7 0.0 1.2 8.2 0.0 2.0 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) Cyt_bd_oxida_II PF02322.15 AAZ33329.1 - 1e-102 343.6 35.8 1.1e-102 343.4 35.8 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit II Mntp PF02659.15 AAZ33330.1 - 6e-54 181.9 17.8 7.8e-54 181.6 11.7 2.0 2 0 0 2 2 2 2 Putative manganese efflux pump Halogen_Hydrol PF10112.9 AAZ33330.1 - 1.5 8.8 0.0 1.5 8.8 0.0 2.3 1 1 1 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein PLDc_2 PF13091.6 AAZ33331.1 - 9.1e-39 132.4 0.0 1.8e-25 89.3 0.0 3.0 3 0 0 3 3 3 2 PLD-like domain PLDc PF00614.22 AAZ33331.1 - 4.9e-14 51.8 0.3 4.6e-08 32.9 0.0 3.1 3 0 0 3 3 3 2 Phospholipase D Active site motif PLDc_N PF13396.6 AAZ33331.1 - 1.8e-06 27.7 1.3 4e-06 26.6 1.3 1.6 1 0 0 1 1 1 1 Phospholipase_D-nuclease N-terminal DUF3010 PF11215.8 AAZ33332.1 - 1.2e-43 148.7 0.1 1.3e-43 148.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3010) MFS_1 PF07690.16 AAZ33333.1 - 5.8e-17 61.7 67.3 8.5e-13 48.0 42.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AAZ33333.1 - 4.5e-07 29.1 4.0 4.5e-07 29.1 4.0 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 AAZ33333.1 - 1.2e-05 24.4 4.8 1.2e-05 24.4 4.8 1.9 2 0 0 2 2 2 1 MFS_1 like family Folate_carrier PF01770.18 AAZ33333.1 - 0.00023 20.0 1.1 0.00023 20.0 1.1 2.5 3 0 0 3 3 3 1 Reduced folate carrier FKBP_C PF00254.28 AAZ33334.1 - 2.9e-26 91.6 0.0 5.4e-26 90.7 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N PF01346.18 AAZ33334.1 - 3.8e-25 88.7 5.2 5.5e-25 88.2 5.2 1.2 1 0 0 1 1 1 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Aldolase PF01081.19 AAZ33335.1 - 1.7e-83 278.8 0.0 2e-83 278.6 0.0 1.0 1 0 0 1 1 1 1 KDPG and KHG aldolase Mur_ligase_M PF08245.12 AAZ33336.1 - 5.1e-47 160.4 0.0 7.4e-47 159.8 0.0 1.2 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 AAZ33336.1 - 5e-11 42.7 1.3 7.1e-11 42.2 0.0 1.9 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain Mur_ligase PF01225.25 AAZ33336.1 - 1.6e-10 41.2 0.1 3.9e-10 39.9 0.1 1.8 1 0 0 1 1 1 1 Mur ligase family, catalytic domain PhageMin_Tail PF10145.9 AAZ33337.1 - 1.2e-24 87.3 20.5 1.2e-24 87.3 20.5 3.2 2 1 1 3 3 3 1 Phage-related minor tail protein WXG100 PF06013.12 AAZ33337.1 - 0.011 16.0 6.5 0.4 11.0 0.1 4.3 4 0 0 4 4 4 0 Proteins of 100 residues with WXG BPD_transp_1 PF00528.22 AAZ33338.1 - 9.3e-10 38.5 2.5 9.3e-10 38.5 2.5 1.9 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF3481 PF11980.8 AAZ33338.1 - 0.01 15.5 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 0 C-terminal domain of neuropilin glycoprotein CstA_5TM PF13722.6 AAZ33338.1 - 0.027 14.8 0.8 0.045 14.1 0.4 1.7 1 1 1 2 2 2 0 5TM C-terminal transporter carbon starvation CstA S_4TM PF18159.1 AAZ33338.1 - 0.96 8.7 2.3 0.5 9.6 0.2 1.6 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain DUF1289 PF06945.13 AAZ33339.1 - 2.2e-19 69.0 4.4 2.6e-19 68.8 4.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1289) Proton_antipo_M PF00361.20 AAZ33340.1 - 2.6e-89 299.3 20.0 2.6e-89 299.3 20.0 2.0 2 0 0 2 2 2 1 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 AAZ33340.1 - 4.9e-21 74.6 1.7 4.9e-21 74.6 1.7 2.5 2 0 0 2 2 2 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus SSF PF00474.17 AAZ33341.1 - 2.2e-18 66.3 29.8 4.5e-18 65.3 29.8 1.5 1 0 0 1 1 1 1 Sodium:solute symporter family DnaJ PF00226.31 AAZ33342.1 - 6.6e-19 67.8 0.2 1.2e-18 66.9 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain Ndc1_Nup PF09531.10 AAZ33342.1 - 1.1 7.8 4.8 1.5 7.4 4.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Y2_Tnp PF04986.13 AAZ33343.1 - 5.4e-47 160.2 1.9 9.5e-47 159.4 1.9 1.4 1 0 0 1 1 1 1 Putative transposase Zn_Tnp_IS91 PF14319.6 AAZ33343.1 - 1.4e-22 79.6 7.3 2.7e-22 78.6 7.3 1.5 1 0 0 1 1 1 1 Transposase zinc-binding domain zf-B_box PF00643.24 AAZ33343.1 - 0.16 12.2 12.7 0.39 10.9 12.7 1.7 1 0 0 1 1 1 0 B-box zinc finger Proteasome PF00227.26 AAZ33344.1 - 4.4e-21 75.2 0.3 8.4e-21 74.3 0.3 1.4 1 1 0 1 1 1 1 Proteasome subunit DUF2288 PF10052.9 AAZ33345.1 - 6.2e-31 106.3 1.2 7e-31 106.2 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2288) Acyl-CoA_dh_1 PF00441.24 AAZ33346.1 - 6.7e-32 110.8 2.1 9.7e-32 110.3 2.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 AAZ33346.1 - 1.5e-20 73.2 0.0 2.3e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 AAZ33346.1 - 6.2e-18 65.5 0.2 1.2e-17 64.6 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 AAZ33346.1 - 1.6e-11 44.6 1.1 3.7e-11 43.4 1.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 AAZ33346.1 - 0.00014 21.7 0.0 0.00031 20.5 0.0 1.6 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal NEL PF14496.6 AAZ33347.1 - 1.3e-59 201.3 0.9 2.7e-59 200.3 0.9 1.6 1 0 0 1 1 1 1 C-terminal novel E3 ligase, LRR-interacting LRR_8 PF13855.6 AAZ33347.1 - 2.9e-07 30.1 14.0 6.3e-05 22.7 2.0 4.0 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 AAZ33347.1 - 0.0001 22.6 9.7 0.0031 17.9 0.6 3.8 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) sCache_3_2 PF17203.4 AAZ33347.1 - 0.017 15.2 0.0 0.055 13.6 0.0 1.8 1 0 0 1 1 1 0 Single cache domain 3 LRR_1 PF00560.33 AAZ33347.1 - 9.4 7.2 13.4 15 6.6 0.2 5.6 4 1 0 4 4 4 0 Leucine Rich Repeat Secretin PF00263.21 AAZ33348.1 - 2.4e-52 177.0 8.5 4.6e-52 176.1 8.5 1.5 1 0 0 1 1 1 1 Bacterial type II and III secretion system protein Secretin_N PF03958.17 AAZ33348.1 - 1e-29 102.7 20.6 4e-08 33.6 0.0 4.9 3 1 0 3 3 3 3 Bacterial type II/III secretion system short domain RP-C PF03428.13 AAZ33348.1 - 0.055 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Replication protein C N-terminal domain HlyD_D23 PF16576.5 AAZ33349.1 - 1.2e-17 63.9 5.2 2e-17 63.1 5.2 1.3 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AAZ33349.1 - 1.2e-12 48.5 6.0 1.3e-10 41.9 0.5 3.4 4 1 0 4 4 4 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AAZ33349.1 - 2.5e-08 33.6 0.5 2.5e-08 33.6 0.5 3.5 4 0 0 4 4 4 2 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AAZ33349.1 - 0.00093 19.0 0.0 1.2 9.1 0.0 2.7 2 0 0 2 2 2 2 Biotin-requiring enzyme PTS_EIIA_1 PF00358.20 AAZ33349.1 - 0.034 13.9 0.0 1 9.1 0.0 2.4 2 0 0 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Peptidase_M23 PF01551.22 AAZ33349.1 - 0.15 12.3 1.4 7.9 6.8 0.0 3.4 3 1 0 3 3 3 0 Peptidase family M23 DUF4355 PF14265.6 AAZ33349.1 - 1.7 8.9 4.3 0.77 10.0 1.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4355) Putative_PNPOx PF01243.20 AAZ33350.1 - 1.6e-26 92.3 0.0 2.5e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 AAZ33350.1 - 6.7e-19 67.7 4.1 1.6e-18 66.5 4.1 1.7 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.7 AAZ33350.1 - 2.8e-09 37.5 0.1 5.1e-09 36.7 0.1 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase TPR_2 PF07719.17 AAZ33351.1 - 0.19 11.9 0.2 0.19 11.9 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 AAZ33351.1 - 0.52 10.6 0.1 0.52 10.6 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat MerR-DNA-bind PF09278.11 AAZ33351.1 - 7.3 7.2 9.7 15 6.2 0.7 3.4 3 1 0 3 3 3 0 MerR, DNA binding HATPase_c PF02518.26 AAZ33352.1 - 2.9e-17 63.2 0.0 9.4e-17 61.5 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAZ33352.1 - 9e-11 41.7 6.8 1e-10 41.5 2.2 2.8 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AAZ33352.1 - 1.1e-07 32.1 0.1 3.8e-07 30.4 0.1 2.0 1 0 0 1 1 1 1 HAMP domain HATPase_c_2 PF13581.6 AAZ33352.1 - 0.00019 21.4 0.5 0.00084 19.3 0.0 2.2 3 0 0 3 3 3 1 Histidine kinase-like ATPase domain PHTB1_C PF14728.6 AAZ33352.1 - 0.048 12.7 0.0 0.079 12.0 0.0 1.2 1 0 0 1 1 1 0 PTHB1 C-terminus DUF948 PF06103.11 AAZ33352.1 - 0.11 12.8 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Na_Ala_symp PF01235.17 AAZ33353.1 - 5.2e-149 496.8 24.9 6.3e-149 496.6 24.9 1.0 1 0 0 1 1 1 1 Sodium:alanine symporter family Hydrolase_6 PF13344.6 AAZ33354.1 - 7.3e-18 64.6 0.0 1.3e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AAZ33354.1 - 1.5e-17 63.4 0.1 4.9e-17 61.8 0.1 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 AAZ33354.1 - 1.8e-08 35.0 3.5 0.0028 18.0 0.1 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 AAZ33354.1 - 8.3e-07 29.3 0.0 0.00014 22.0 0.0 2.5 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase ADH_zinc_N PF00107.26 AAZ33355.1 - 7.2e-31 106.9 0.2 1.5e-30 105.9 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AAZ33355.1 - 1.4e-23 84.4 0.0 3.1e-23 83.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AAZ33355.1 - 1.7e-12 47.1 0.0 1.6e-11 44.0 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 AAZ33355.1 - 0.003 17.0 0.3 0.0049 16.4 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase AlaDh_PNT_C PF01262.21 AAZ33355.1 - 0.003 16.9 1.4 0.0049 16.2 1.4 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Eno-Rase_NADH_b PF12242.8 AAZ33355.1 - 0.013 15.2 0.1 0.048 13.4 0.1 2.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase TrkA_N PF02254.18 AAZ33355.1 - 0.061 13.6 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 AAZ33355.1 - 0.089 12.1 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ACP_syn_III_C PF08541.10 AAZ33355.1 - 0.56 10.4 2.5 1.7 8.8 0.4 2.6 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal AcetylCoA_hyd_C PF13336.6 AAZ33356.1 - 2.7e-42 144.3 0.0 5.1e-42 143.4 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 AAZ33356.1 - 1.3e-29 103.6 0.0 3e-29 102.4 0.0 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain CitF PF04223.12 AAZ33356.1 - 1.4e-05 24.2 0.6 1.4e-05 24.2 0.6 1.9 2 1 1 3 3 3 1 Citrate lyase, alpha subunit (CitF) CoA_trans PF01144.23 AAZ33356.1 - 1.8e-05 24.2 0.4 0.00033 20.1 0.1 2.3 1 1 1 2 2 2 1 Coenzyme A transferase LUD_dom PF02589.15 AAZ33356.1 - 5.1e-05 23.1 0.1 8.1e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 LUD domain TP_methylase PF00590.20 AAZ33357.1 - 3.5e-28 99.0 0.3 5.7e-28 98.3 0.3 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Flg_hook PF02120.16 AAZ33358.1 - 2.8e-16 59.2 0.0 2.3e-15 56.2 0.0 2.7 2 0 0 2 2 2 1 Flagellar hook-length control protein FliK Peptidase_M24 PF00557.24 AAZ33359.1 - 1.9e-42 145.3 0.0 2.7e-42 144.9 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.5 AAZ33359.1 - 2.3e-39 135.1 0.0 9.4e-39 133.1 0.0 1.9 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 AAZ33359.1 - 8e-24 83.5 0.6 3e-23 81.7 0.4 2.2 3 0 0 3 3 3 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 AAZ33359.1 - 5.3e-16 59.5 0.0 4.1e-12 46.9 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain DUF1177 PF06675.11 AAZ33359.1 - 0.12 11.1 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1177) Response_reg PF00072.24 AAZ33361.1 - 1.9e-21 76.3 0.0 7e-18 64.8 0.0 2.8 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 AAZ33361.1 - 2e-19 70.1 0.0 4.2e-19 69.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 AAZ33361.1 - 6e-14 52.1 0.1 2.8e-13 50.0 0.0 2.2 2 0 0 2 2 2 1 PAS fold HisKA PF00512.25 AAZ33361.1 - 8.7e-08 32.1 0.6 8.7e-08 32.1 0.6 4.4 6 0 0 6 6 6 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 AAZ33361.1 - 0.0014 18.8 0.0 0.0049 17.1 0.0 2.0 1 0 0 1 1 1 1 PAS fold HPTransfase PF10090.9 AAZ33361.1 - 0.005 16.6 0.1 0.014 15.2 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphotransferase C-terminal domain OmpH PF03938.14 AAZ33361.1 - 0.059 13.7 0.5 0.18 12.1 0.2 1.9 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) HATPase_c_3 PF13589.6 AAZ33361.1 - 0.14 12.0 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1244 PF06844.11 AAZ33362.1 - 1.4e-36 124.5 1.3 1.8e-36 124.1 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1244) Terminase_4 PF05119.12 AAZ33362.1 - 0.0022 18.4 0.2 0.0028 18.1 0.2 1.2 1 0 0 1 1 1 1 Phage terminase, small subunit DUF4186 PF13811.6 AAZ33362.1 - 0.09 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4186) adh_short_C2 PF13561.6 AAZ33363.1 - 1e-71 241.2 0.5 1.2e-71 241.0 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAZ33363.1 - 3.1e-57 193.2 0.9 3.6e-57 193.0 0.9 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAZ33363.1 - 1.4e-14 54.4 0.7 1.8e-14 54.1 0.7 1.1 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 AAZ33363.1 - 1.6e-07 31.7 0.2 2.7e-07 30.9 0.2 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 AAZ33363.1 - 0.00031 20.8 1.0 0.0016 18.5 1.0 2.1 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 AAZ33363.1 - 0.001 19.0 0.5 0.0016 18.4 0.5 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 AAZ33363.1 - 0.0012 18.4 0.1 0.0054 16.2 0.2 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 AAZ33363.1 - 0.011 16.3 0.2 0.021 15.4 0.2 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 AAZ33363.1 - 0.035 13.5 0.1 0.059 12.7 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 AAZ33363.1 - 0.052 14.0 0.5 0.086 13.3 0.5 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Polysacc_synt_2 PF02719.15 AAZ33363.1 - 0.057 12.5 0.0 0.082 12.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 AAZ33363.1 - 0.088 11.9 0.1 0.35 9.9 0.1 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain GIDA PF01134.22 AAZ33363.1 - 0.11 11.5 0.5 0.17 10.9 0.5 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A ApbA PF02558.16 AAZ33363.1 - 0.12 12.0 0.1 0.17 11.5 0.1 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NmrA PF05368.13 AAZ33363.1 - 0.47 10.0 2.0 0.69 9.4 1.5 1.5 2 0 0 2 2 2 0 NmrA-like family CYTH PF01928.21 AAZ33364.1 - 4.5e-34 117.9 1.5 6.6e-34 117.4 1.0 1.5 2 0 0 2 2 2 1 CYTH domain ABC_tran PF00005.27 AAZ33365.1 - 3.8e-32 111.6 0.0 5.9e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 AAZ33365.1 - 2.3e-05 24.9 0.1 4.7e-05 23.8 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AAZ33365.1 - 4.5e-05 23.7 0.0 0.00013 22.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 AAZ33365.1 - 0.00042 19.2 0.1 0.057 12.2 0.0 2.2 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_21 PF13304.6 AAZ33365.1 - 0.0019 18.1 0.0 0.41 10.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AAZ33365.1 - 0.002 17.8 0.2 0.0039 16.9 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AAZ33365.1 - 0.0054 16.7 0.1 0.011 15.7 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_33 PF13671.6 AAZ33365.1 - 0.01 16.0 0.0 0.019 15.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 AAZ33365.1 - 0.019 14.9 0.2 0.085 12.8 0.2 2.0 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea SMC_N PF02463.19 AAZ33365.1 - 0.034 13.6 0.1 0.5 9.8 0.1 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_14 PF13173.6 AAZ33365.1 - 0.044 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AAZ33365.1 - 0.054 13.2 0.0 0.091 12.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AAZ33365.1 - 0.07 12.8 0.0 0.43 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 AAZ33365.1 - 0.084 12.0 0.0 0.084 12.0 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit APS_kinase PF01583.20 AAZ33365.1 - 0.085 12.7 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_23 PF13476.6 AAZ33365.1 - 0.089 13.3 0.1 0.19 12.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 AAZ33365.1 - 0.093 13.1 0.0 4.3 7.8 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AAZ33365.1 - 0.096 12.7 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 AAZ33365.1 - 0.12 12.9 0.0 0.3 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 AAZ33365.1 - 0.14 12.5 0.6 0.32 11.2 0.6 1.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Adeno_IVa2 PF02456.15 AAZ33365.1 - 0.15 10.8 0.0 0.28 9.9 0.0 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein Zeta_toxin PF06414.12 AAZ33365.1 - 0.17 11.2 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin HAD PF12710.7 AAZ33366.1 - 1.1e-34 120.4 0.0 1.4e-34 120.2 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase GlcNAc_2-epim PF07221.11 AAZ33368.1 - 2e-41 142.4 0.9 2.7e-41 142.0 0.9 1.2 1 0 0 1 1 1 1 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) GreA_GreB PF01272.19 AAZ33369.1 - 9.7e-05 22.2 0.1 0.00024 20.9 0.1 1.6 1 1 0 1 1 1 1 Transcription elongation factor, GreA/GreB, C-term HAD_2 PF13419.6 AAZ33370.1 - 6.3e-26 91.5 0.0 7.9e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAZ33370.1 - 1.2e-11 45.3 0.0 1.3e-11 45.2 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AAZ33370.1 - 9.6e-06 25.6 0.0 1.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 AAZ33370.1 - 0.00054 20.4 0.0 0.00066 20.1 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase SBP_bac_6 PF13343.6 AAZ33371.1 - 2.3e-32 112.3 2.0 3.1e-32 112.0 2.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 AAZ33371.1 - 3.7e-11 43.4 8.9 3.7e-11 43.4 8.9 2.4 1 1 2 3 3 3 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 AAZ33371.1 - 5.1e-07 29.7 1.9 1.8e-06 27.9 1.9 1.9 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein GST_C_4 PF14834.6 AAZ33371.1 - 0.11 12.8 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain 2Fe-2S_thioredx PF01257.19 AAZ33372.1 - 3.5e-49 166.4 0.0 4e-49 166.2 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Alpha-amylase PF00128.24 AAZ33373.1 - 9.9e-18 64.8 0.0 5.1e-12 46.0 0.0 3.2 3 0 0 3 3 3 3 Alpha amylase, catalytic domain Peptidase_M23 PF01551.22 AAZ33374.1 - 9.5e-33 112.3 4.0 9.5e-33 112.3 4.0 2.5 3 0 0 3 3 3 1 Peptidase family M23 OapA PF04225.12 AAZ33374.1 - 6e-08 32.7 0.5 3.4e-07 30.3 0.1 2.3 2 0 0 2 2 2 1 Opacity-associated protein A LysM-like domain SNF2_assoc PF08455.10 AAZ33374.1 - 0.004 16.2 0.0 0.0059 15.7 0.0 1.2 1 0 0 1 1 1 1 Bacterial SNF2 helicase associated tRNA_synt_1c_R1 PF04558.15 AAZ33374.1 - 0.058 13.4 0.7 0.21 11.6 0.2 2.1 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Csd3_N PF18059.1 AAZ33374.1 - 0.081 13.5 0.1 0.38 11.3 0.0 2.0 2 0 0 2 2 2 0 Csd3 N-terminal Phage_integrase PF00589.22 AAZ33375.1 - 0.027 14.3 0.0 0.077 12.8 0.0 1.8 1 0 0 1 1 1 0 Phage integrase family IMS PF00817.20 AAZ33376.1 - 3.3e-18 66.1 0.0 1.8e-17 63.7 0.0 2.1 2 0 0 2 2 2 1 impB/mucB/samB family DUF4113 PF13438.6 AAZ33376.1 - 5.7e-18 64.7 1.1 1.3e-17 63.6 1.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4113) IMS_C PF11799.8 AAZ33376.1 - 6.5e-12 46.2 0.0 1.7e-11 44.8 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 AAZ33376.1 - 0.00012 22.1 0.0 0.00045 20.4 0.0 2.0 1 0 0 1 1 1 1 IMS family HHH motif Cdd1 PF11731.8 AAZ33376.1 - 0.02 15.1 0.0 0.085 13.1 0.0 2.0 2 0 0 2 2 2 0 Pathogenicity locus DUF4332 PF14229.6 AAZ33376.1 - 0.041 14.1 0.1 0.14 12.4 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) DUF2236 PF09995.9 AAZ33378.1 - 2e-52 178.7 4.2 2.5e-52 178.3 4.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) rve PF00665.26 AAZ33379.1 - 0.00051 20.2 0.0 0.0012 19.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain HTH_23 PF13384.6 AAZ33379.1 - 0.0031 17.3 0.0 0.45 10.4 0.0 2.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 AAZ33379.1 - 0.0047 17.0 0.0 0.19 11.9 0.0 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain Homeodomain PF00046.29 AAZ33379.1 - 0.012 15.4 0.0 0.034 14.0 0.0 1.7 1 0 0 1 1 1 0 Homeodomain Mu-transpos_C PF09299.11 AAZ33379.1 - 0.026 14.5 0.0 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 Mu transposase, C-terminal GerE PF00196.19 AAZ33379.1 - 0.12 11.9 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family TOBE_3 PF12857.7 AAZ33380.1 - 0.086 12.8 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 TOBE-like domain K_oxygenase PF13434.6 AAZ33381.1 - 7.1e-77 258.8 0.0 8.4e-77 258.6 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 AAZ33381.1 - 6.6e-08 32.2 0.0 0.0038 16.5 0.0 3.1 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 AAZ33381.1 - 0.00011 21.6 0.0 0.0074 15.5 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.25 AAZ33382.1 - 8.3e-42 142.9 0.3 1.4e-41 142.1 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAZ33382.1 - 1.3e-33 116.5 0.5 1.8e-33 116.0 0.5 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAZ33382.1 - 7.1e-18 65.1 0.5 1e-17 64.7 0.5 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AAZ33382.1 - 0.0011 18.5 0.3 0.0016 17.9 0.3 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 AAZ33382.1 - 0.03 14.2 1.3 0.14 12.0 1.3 2.0 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pirin PF02678.16 AAZ33383.1 - 1.7e-37 127.7 0.4 5.8e-37 126.0 0.3 2.0 3 0 0 3 3 3 1 Pirin Pirin_C PF05726.13 AAZ33383.1 - 1.1e-34 118.9 0.0 1.4e-33 115.3 0.0 2.5 3 0 0 3 3 3 1 Pirin C-terminal cupin domain Pirin_C_2 PF17954.1 AAZ33383.1 - 0.0059 16.8 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 Quercetinase C-terminal cupin domain ketoacyl-synt PF00109.26 AAZ33384.1 - 1.5e-58 198.4 0.7 2.3e-58 197.8 0.7 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 AAZ33384.1 - 1e-39 135.2 0.8 1.9e-39 134.3 0.8 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 AAZ33384.1 - 0.04 13.3 3.7 0.052 12.9 0.5 2.5 3 0 0 3 3 3 0 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 AAZ33384.1 - 0.096 13.1 0.0 0.29 11.6 0.0 1.8 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension ACP_syn_III PF08545.10 AAZ33384.1 - 0.14 12.0 0.0 0.14 12.0 0.0 3.0 3 1 1 4 4 4 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Cellulase PF00150.18 AAZ33385.1 - 1e-11 44.8 1.6 2.1e-11 43.8 1.6 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 AAZ33385.1 - 5.8e-05 22.6 0.1 0.0002 20.8 0.0 1.8 2 0 0 2 2 2 1 Beta-galactosidase Glyco_hydro_35 PF01301.19 AAZ33385.1 - 0.024 14.3 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 CMD PF02627.20 AAZ33386.1 - 1.9e-25 88.7 0.1 2.8e-25 88.2 0.1 1.3 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Alanine_zipper PF11839.8 AAZ33387.1 - 1.1e-09 38.5 22.3 1.5e-09 38.1 22.3 1.2 1 0 0 1 1 1 1 Alanine-zipper, major outer membrane lipoprotein SMBP PF16785.5 AAZ33387.1 - 0.022 15.0 7.0 0.024 14.9 7.0 1.0 1 0 0 1 1 1 0 Small metal-binding protein CMV_US PF08001.11 AAZ33387.1 - 0.11 11.7 0.5 0.13 11.6 0.5 1.1 1 0 0 1 1 1 0 CMV US RHS_repeat PF05593.14 AAZ33388.1 - 1.1e-45 153.6 67.8 1.9e-06 28.3 2.4 18.3 14 3 4 19 19 19 15 RHS Repeat RHS PF03527.14 AAZ33388.1 - 3.6e-21 74.6 1.2 1.6e-18 66.2 0.1 3.9 3 0 0 3 3 3 1 RHS protein PAAR_motif PF05488.13 AAZ33388.1 - 1.2e-18 67.0 3.1 5.9e-18 64.8 0.4 2.0 1 1 1 2 2 2 2 PAAR motif DUF4595 PF15283.6 AAZ33388.1 - 1.3e-08 35.2 21.0 0.092 12.8 0.1 6.9 4 2 1 6 6 6 4 Domain of unknown function (DUF4595) with porin-like fold Imm71 PF15602.6 AAZ33388.1 - 0.23 11.5 3.2 2.2 8.3 0.0 2.8 3 0 0 3 3 3 0 Immunity protein 71 COX1 PF00115.20 AAZ33389.1 - 1.7e-135 452.2 68.5 1.7e-135 452.2 68.5 2.3 3 0 0 3 3 3 1 Cytochrome C and Quinol oxidase polypeptide I Glyco_hydro_3 PF00933.21 AAZ33390.1 - 4.8e-85 285.7 0.2 6.4e-85 285.3 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 AAZ33390.1 - 4e-61 206.5 0.1 6.2e-61 205.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 AAZ33390.1 - 7.4e-22 77.2 0.0 1.4e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PHP PF02811.19 AAZ33390.1 - 0.0095 16.2 0.0 0.026 14.8 0.0 1.8 1 0 0 1 1 1 1 PHP domain Ig_GlcNase PF18368.1 AAZ33390.1 - 0.027 14.6 0.1 0.067 13.3 0.1 1.6 1 0 0 1 1 1 0 Exo-beta-D-glucosaminidase Ig-fold domain CARDB PF07705.11 AAZ33390.1 - 0.029 14.6 0.0 0.066 13.5 0.0 1.6 1 0 0 1 1 1 0 CARDB cobW PF02492.19 AAZ33391.1 - 9e-56 188.2 0.1 1.1e-55 187.9 0.1 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 AAZ33391.1 - 8.8e-28 96.1 0.1 2.6e-27 94.6 0.1 1.8 2 0 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 AAZ33391.1 - 1.9e-05 24.6 0.1 0.03 14.2 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase T2SSE PF00437.20 AAZ33391.1 - 0.01 14.9 0.0 0.054 12.5 0.0 2.0 1 1 1 2 2 2 0 Type II/IV secretion system protein AAA_16 PF13191.6 AAZ33391.1 - 0.016 15.6 0.0 0.036 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 AAZ33391.1 - 0.026 15.0 0.0 0.045 14.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.23 AAZ33391.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase MeaB PF03308.16 AAZ33391.1 - 0.12 11.3 0.0 0.5 9.3 0.0 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 AAZ33391.1 - 0.16 12.1 0.0 0.7 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF1656 PF07869.12 AAZ33392.1 - 1.7e-20 72.8 10.3 2e-20 72.5 10.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1656) Acetyltransf_4 PF13420.7 AAZ33393.1 - 6.5e-20 71.8 0.0 7.4e-20 71.6 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAZ33393.1 - 1.1e-16 61.2 0.0 1.3e-16 60.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 AAZ33393.1 - 2.1e-13 51.2 0.0 2.5e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAZ33393.1 - 1.2e-08 34.8 0.0 2e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 AAZ33393.1 - 7.1e-08 32.4 0.0 9.4e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAZ33393.1 - 1.2e-06 28.8 0.0 1.6e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 AAZ33393.1 - 0.00051 19.7 0.0 0.00066 19.3 0.0 1.1 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_CG PF14542.6 AAZ33393.1 - 0.041 14.0 0.0 0.063 13.4 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.6 AAZ33393.1 - 0.054 13.2 0.1 0.11 12.2 0.0 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain CMAS PF02353.20 AAZ33394.1 - 5.6e-89 298.1 0.2 7e-89 297.7 0.2 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 AAZ33394.1 - 1.5e-08 35.2 0.0 1.1e-07 32.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAZ33394.1 - 7.4e-07 29.1 0.0 2.7e-06 27.3 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAZ33394.1 - 1.7e-06 28.6 0.0 3.6e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAZ33394.1 - 3.7e-06 27.6 0.0 9.9e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 AAZ33394.1 - 0.00028 20.9 0.0 0.00055 19.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DOT1 PF08123.13 AAZ33394.1 - 0.022 14.3 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 DUF938 PF06080.12 AAZ33394.1 - 0.067 12.9 0.0 0.3 10.8 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF938) MTS PF05175.14 AAZ33394.1 - 0.092 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.19 AAZ33394.1 - 0.11 12.3 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 AAZ33394.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase SBP_bac_3 PF00497.20 AAZ33395.1 - 1.3e-10 41.1 0.0 1.6e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 DNTTIP1_dimer PF18192.1 AAZ33395.1 - 0.18 12.2 0.0 0.38 11.1 0.0 1.4 1 0 0 1 1 1 0 DNTTIP1 dimerisation domain SBP_bac_8 PF13416.6 AAZ33396.1 - 5.2e-30 105.2 4.4 6.3e-30 104.9 4.4 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AAZ33396.1 - 9.8e-22 77.5 0.6 1.4e-21 77.1 0.6 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AAZ33396.1 - 1.3e-11 45.0 8.3 4.4e-11 43.3 8.7 1.7 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 AAZ33396.1 - 0.00021 21.1 0.0 0.0015 18.3 0.0 2.2 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein DUF2845 PF11006.8 AAZ33397.1 - 7.3e-22 77.3 0.1 9.8e-22 76.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2845) AstB PF04996.12 AAZ33398.1 - 5.9e-223 740.4 0.0 6.6e-223 740.2 0.0 1.0 1 0 0 1 1 1 1 Succinylarginine dihydrolase SBP_bac_3 PF00497.20 AAZ33399.1 - 1.3e-46 158.9 0.1 1.6e-46 158.6 0.1 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 AAZ33399.1 - 4e-05 23.8 0.0 0.00012 22.2 0.0 1.8 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site SDH_C PF18317.1 AAZ33399.1 - 0.16 11.7 3.4 0.19 11.5 0.1 2.9 4 0 0 4 4 4 0 Shikimate 5'-dehydrogenase C-terminal domain RRF PF01765.19 AAZ33400.1 - 1.4e-55 187.6 1.6 1.5e-55 187.5 0.3 1.6 1 1 1 2 2 2 1 Ribosome recycling factor SpoIIIAH PF12685.7 AAZ33400.1 - 0.011 15.6 3.5 0.012 15.4 3.5 1.3 1 1 0 1 1 1 0 SpoIIIAH-like protein DUF4168 PF13767.6 AAZ33400.1 - 0.011 16.8 1.6 1.6 9.9 2.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4168) YtxH PF12732.7 AAZ33400.1 - 0.24 12.0 4.6 1.7 9.2 4.8 2.2 2 1 0 2 2 2 0 YtxH-like protein COX4_pro PF03626.14 AAZ33401.1 - 3.8e-17 62.5 13.4 5e-17 62.1 13.4 1.2 1 0 0 1 1 1 1 Prokaryotic Cytochrome C oxidase subunit IV ABC2_membrane_5 PF13346.6 AAZ33401.1 - 0.011 15.3 10.2 0.013 15.1 10.2 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF983 PF06170.12 AAZ33401.1 - 0.11 12.9 6.6 0.97 9.9 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF983) LRR19-TM PF15176.6 AAZ33401.1 - 1.9 8.5 5.4 11 6.0 0.1 2.5 2 1 1 3 3 3 0 Leucine-rich repeat family 19 TM domain GSP_synth PF03738.14 AAZ33402.1 - 1.4e-06 27.7 0.1 0.00056 19.2 0.0 2.0 2 0 0 2 2 2 2 Glutathionylspermidine synthase preATP-grasp CP_ATPgrasp_2 PF14403.6 AAZ33402.1 - 7.6e-05 21.8 0.0 0.00011 21.3 0.0 1.2 1 0 0 1 1 1 1 Circularly permuted ATP-grasp type 2 GSH-S_ATP PF02955.16 AAZ33402.1 - 0.00064 19.2 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATPgrasp_YheCD PF14398.6 AAZ33402.1 - 0.0078 15.5 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 YheC/D like ATP-grasp DUF4096 PF13340.6 AAZ33404.1 - 2.9e-25 88.3 0.4 6.6e-25 87.1 0.4 1.6 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1 PF01609.21 AAZ33404.1 - 0.03 13.9 0.0 0.056 13.1 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain HTH_Tnp_Tc3_2 PF01498.18 AAZ33404.1 - 0.036 14.3 0.0 0.072 13.3 0.0 1.4 1 0 0 1 1 1 0 Transposase HpcH_HpaI PF03328.14 AAZ33405.1 - 6.7e-35 120.2 0.1 8.6e-35 119.9 0.1 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Amidohydro_1 PF01979.20 AAZ33406.1 - 1.5e-43 149.5 0.4 1.8e-43 149.2 0.4 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AAZ33406.1 - 2.1e-14 53.9 3.9 1.6e-06 27.9 1.2 2.3 2 0 0 2 2 2 2 Amidohydrolase family LysR_substrate PF03466.20 AAZ33407.1 - 7.1e-41 139.9 1.1 9.3e-41 139.5 1.1 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ33407.1 - 2.9e-21 75.2 1.0 7e-21 74.0 1.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family SMP_2 PF10144.9 AAZ33408.1 - 5.2e-07 29.4 3.3 2.6e-06 27.2 3.3 2.0 1 1 0 1 1 1 1 Bacterial virulence factor haemolysin HAMP PF00672.25 AAZ33408.1 - 0.059 13.7 0.1 0.19 12.1 0.1 1.9 1 0 0 1 1 1 0 HAMP domain DctQ PF04290.12 AAZ33408.1 - 0.061 13.2 1.4 1.3 9.0 0.2 2.2 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Glycos_trans_3N PF02885.17 AAZ33409.1 - 1.3e-17 63.4 0.6 2.4e-17 62.5 0.2 1.6 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain Glycos_transf_3 PF00591.21 AAZ33409.1 - 0.0035 17.0 0.0 0.0055 16.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Amidohydro_1 PF01979.20 AAZ33410.1 - 9.3e-58 196.2 0.0 1.2e-57 195.9 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AAZ33410.1 - 1.8e-11 44.2 0.2 1.4e-07 31.4 0.0 2.3 1 1 1 2 2 2 2 Amidohydrolase family PfkB PF00294.24 AAZ33411.1 - 2.5e-73 247.0 6.0 2.9e-73 246.8 6.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 AAZ33411.1 - 2.9e-10 40.0 0.5 4.8e-10 39.2 0.5 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Asparaginase_C PF17763.1 AAZ33411.1 - 0.067 13.4 1.1 0.16 12.2 0.3 1.9 1 1 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain SBP_bac_8 PF13416.6 AAZ33413.1 - 2.9e-27 96.2 1.0 3.6e-27 95.9 1.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AAZ33413.1 - 8.8e-22 77.7 0.8 1.2e-21 77.3 0.8 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 AAZ33413.1 - 9.6e-17 61.5 0.5 1.5e-16 60.9 0.5 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AAZ33413.1 - 1.1e-09 38.7 1.3 2.8e-09 37.4 1.3 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein DUF1846 PF08903.11 AAZ33413.1 - 0.013 14.0 0.0 0.045 12.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1846) Phi29_Phage_SSB PF17427.2 AAZ33413.1 - 0.11 12.6 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 Phage Single-stranded DNA-binding protein Response_reg PF00072.24 AAZ33414.1 - 2.1e-24 85.8 0.0 3.1e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAZ33414.1 - 1.6e-18 66.6 0.1 4.1e-17 62.0 0.0 2.3 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal Transposase_mut PF00872.18 AAZ33415.1 - 5.8e-117 390.8 0.0 7.3e-117 390.4 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ33415.1 - 7.8e-05 23.0 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain DUF4844 PF16133.5 AAZ33415.1 - 0.23 12.0 0.0 0.55 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) Formyl_trans_N PF00551.19 AAZ33416.1 - 1e-34 119.8 0.0 1.3e-34 119.5 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.25 AAZ33416.1 - 0.054 13.3 0.0 0.16 11.7 0.0 1.9 1 0 0 1 1 1 0 ACT domain ACT_6 PF13740.6 AAZ33416.1 - 0.079 13.0 0.0 0.21 11.6 0.0 1.8 1 0 0 1 1 1 0 ACT domain Lactamase_B_2 PF12706.7 AAZ33417.1 - 4e-50 170.1 0.0 4.8e-50 169.9 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain PAAR_motif PF05488.13 AAZ33418.1 - 7.2e-18 64.5 2.9 8.4e-18 64.3 2.9 1.1 1 0 0 1 1 1 1 PAAR motif DsrH PF04077.12 AAZ33419.1 - 1.1e-21 76.7 0.0 1.3e-21 76.5 0.0 1.0 1 0 0 1 1 1 1 DsrH like protein RNA_pol_Rpb6 PF01192.22 AAZ33420.1 - 2.5e-17 62.5 0.3 1.2e-16 60.3 0.0 1.9 1 1 1 2 2 2 1 RNA polymerase Rpb6 GAD-like PF08887.11 AAZ33421.1 - 2e-38 130.4 0.3 2.8e-38 130.0 0.3 1.2 1 0 0 1 1 1 1 GAD-like domain DUF1851 PF08906.11 AAZ33421.1 - 1.9e-20 72.6 0.2 4.2e-20 71.5 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1851) tRNA-synt_2 PF00152.20 AAZ33422.1 - 5.6e-83 278.6 0.3 7.1e-83 278.3 0.3 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 AAZ33422.1 - 5.1e-09 36.0 0.2 1.5e-08 34.5 0.1 1.8 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 AAZ33422.1 - 1.3e-05 24.8 1.7 0.0058 16.2 0.2 2.8 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) ACCA PF03255.14 AAZ33423.1 - 2.3e-64 215.6 0.0 3.5e-64 215.0 0.0 1.3 1 0 0 1 1 1 1 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Carboxyl_trans PF01039.22 AAZ33423.1 - 3.5e-17 62.2 0.0 3.8e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain ECH_1 PF00378.20 AAZ33423.1 - 0.14 11.5 0.5 0.49 9.7 0.5 1.8 1 1 0 1 1 1 0 Enoyl-CoA hydratase/isomerase Ribosomal_S7 PF00177.21 AAZ33424.1 - 8e-67 223.5 3.8 8.9e-67 223.4 3.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DUF4443 PF14544.6 AAZ33425.1 - 0.018 15.3 0.1 0.052 13.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4443) AAA_16 PF13191.6 AAZ33425.1 - 0.058 13.8 1.0 0.19 12.1 0.0 2.4 2 2 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 AAZ33425.1 - 0.088 12.5 0.2 0.32 10.7 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 AAZ33425.1 - 0.12 12.4 0.0 1.9 8.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain Asp_protease PF09668.10 AAZ33425.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Peripla_BP_4 PF13407.6 AAZ33426.1 - 4.8e-56 190.2 11.6 5.8e-56 189.9 11.6 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 AAZ33426.1 - 8.5e-12 45.1 1.4 1e-11 44.8 1.4 1.2 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_3 PF13377.6 AAZ33426.1 - 2e-10 41.2 0.0 3.5e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein-like domain Peripla_BP_6 PF13458.6 AAZ33426.1 - 0.022 14.5 4.3 0.063 12.9 4.1 1.9 1 1 0 1 1 1 0 Periplasmic binding protein HATPase_c PF02518.26 AAZ33427.1 - 9.1e-25 87.3 0.0 1.8e-24 86.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAZ33427.1 - 6.2e-12 45.4 0.1 2e-11 43.7 0.1 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AAZ33427.1 - 3.5e-09 36.9 0.1 9.8e-09 35.5 0.1 1.8 1 0 0 1 1 1 1 HAMP domain HATPase_c_5 PF14501.6 AAZ33427.1 - 1e-06 28.5 0.0 2.2e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 GHKL domain HATPase_c_2 PF13581.6 AAZ33427.1 - 0.00011 22.2 0.1 0.00041 20.3 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain FH2 PF02181.23 AAZ33427.1 - 0.013 14.7 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain HemY_N PF07219.13 AAZ33427.1 - 1.4 9.2 4.4 15 5.8 1.0 2.7 3 0 0 3 3 3 0 HemY protein N-terminus DUF1656 PF07869.12 AAZ33427.1 - 4.9 7.2 10.4 0.086 12.9 2.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) BPD_transp_2 PF02653.16 AAZ33428.1 - 5.7e-40 137.2 32.0 8.5e-40 136.6 32.0 1.2 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component NiFe_hyd_3_EhaA PF17367.2 AAZ33428.1 - 0.046 13.9 1.1 0.046 13.9 1.1 2.9 3 0 0 3 3 3 0 NiFe-hydrogenase-type-3 Eha complex subunit A DNA_binding_1 PF01035.20 AAZ33429.1 - 2.2e-32 111.0 0.1 4.8e-32 109.9 0.1 1.6 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Ada_Zn_binding PF02805.16 AAZ33429.1 - 1.7e-21 76.0 0.0 3.4e-21 75.0 0.0 1.5 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_18 PF12833.7 AAZ33429.1 - 5e-17 61.9 0.5 8.6e-16 58.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAZ33429.1 - 9.1e-17 60.7 0.3 9.9e-09 35.1 0.0 2.8 3 0 0 3 3 3 2 Bacterial regulatory helix-turn-helix proteins, AraC family Transposase_20 PF02371.16 AAZ33429.1 - 0.01 16.1 0.2 0.091 13.1 0.1 2.2 1 1 1 2 2 2 0 Transposase IS116/IS110/IS902 family Methyltransf_1N PF02870.15 AAZ33429.1 - 0.071 13.9 0.0 0.13 13.1 0.0 1.4 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain Dodecin PF07311.12 AAZ33431.1 - 5.1e-30 103.5 0.4 5.6e-30 103.4 0.4 1.0 1 0 0 1 1 1 1 Dodecin Jag_N PF14804.6 AAZ33431.1 - 0.11 12.9 0.1 0.16 12.3 0.1 1.4 1 0 0 1 1 1 0 Jag N-terminus DNA_circ_N PF07157.12 AAZ33434.1 - 2.8e-31 107.7 0.0 6.3e-31 106.6 0.0 1.6 1 0 0 1 1 1 1 DNA circularisation protein N-terminus Phasin PF05597.11 AAZ33434.1 - 0.061 13.3 0.1 0.14 12.2 0.1 1.7 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF3483 PF11982.8 AAZ33435.1 - 1.1e-91 306.3 13.7 1.5e-91 305.9 13.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3483) CCG PF02754.16 AAZ33435.1 - 5.9e-20 71.3 0.0 1.8e-13 50.5 0.0 2.4 2 0 0 2 2 2 2 Cysteine-rich domain Fer4_8 PF13183.6 AAZ33435.1 - 5.2e-12 46.0 1.2 1.2e-11 44.8 1.2 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAZ33435.1 - 1.1e-10 41.4 3.0 1.1e-10 41.4 3.0 2.0 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAZ33435.1 - 1.7e-08 34.5 5.0 1.7e-08 34.5 5.0 2.3 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_4 PF12800.7 AAZ33435.1 - 2.2e-06 27.7 15.6 0.00063 20.1 1.9 3.3 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_2 PF12797.7 AAZ33435.1 - 9.5e-06 25.4 11.7 0.0014 18.6 2.1 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 AAZ33435.1 - 3.2e-05 24.4 12.9 0.00013 22.5 10.5 2.7 2 1 1 3 3 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 AAZ33435.1 - 3.5e-05 23.7 16.0 0.0014 18.6 4.7 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 AAZ33435.1 - 7.3e-05 23.3 10.5 7.3e-05 23.3 10.5 2.4 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4 PF00037.27 AAZ33435.1 - 9.3e-05 22.1 16.7 0.0054 16.5 4.7 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 AAZ33435.1 - 0.00037 21.4 11.0 0.062 14.2 2.0 2.7 3 0 0 3 3 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 AAZ33435.1 - 0.0088 16.2 10.1 0.14 12.3 0.5 2.8 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_18 PF13746.6 AAZ33435.1 - 0.019 15.1 3.1 0.5 10.6 0.2 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 AAZ33435.1 - 0.095 13.6 7.4 0.27 12.1 0.2 3.2 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 AAZ33435.1 - 3.3 8.5 11.2 1 10.2 0.2 3.5 3 1 1 4 4 4 0 4Fe-4S single cluster domain Fer4_13 PF13370.6 AAZ33435.1 - 4.5 7.9 14.1 4.5 7.9 1.8 2.6 3 0 0 3 3 2 0 4Fe-4S single cluster domain of Ferredoxin I DNA_pol3_alpha PF07733.12 AAZ33436.1 - 3.7e-102 341.4 0.0 5.9e-102 340.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha NTPase domain DNA_pol3_finger PF17657.1 AAZ33436.1 - 2.3e-65 219.0 0.0 9.3e-65 217.0 0.0 2.1 2 0 0 2 2 2 1 Bacterial DNA polymerase III alpha subunit finger domain PHP PF02811.19 AAZ33436.1 - 5.3e-42 143.9 0.0 1.1e-41 142.9 0.0 1.6 1 0 0 1 1 1 1 PHP domain HHH_6 PF14579.6 AAZ33436.1 - 4e-24 84.7 0.0 1.2e-23 83.2 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif tRNA_anti-codon PF01336.25 AAZ33436.1 - 6.9e-09 35.6 0.0 1.7e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 AAZ33436.1 - 0.0059 16.8 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Acetyltransf_1 PF00583.25 AAZ33437.1 - 3.8e-11 43.2 0.0 5.2e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 AAZ33437.1 - 5.2e-09 36.9 0.0 7.3e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAZ33437.1 - 1.5e-08 35.0 0.0 1.8e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAZ33437.1 - 5.7e-07 29.5 0.0 6.9e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AAZ33437.1 - 1.9e-06 28.1 0.0 2.6e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 AAZ33437.1 - 0.022 14.4 0.0 0.098 12.3 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAZ33437.1 - 0.066 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein AMP-binding PF00501.28 AAZ33438.1 - 1.7e-60 204.9 0.0 2.5e-60 204.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAZ33438.1 - 6e-08 33.6 0.0 1.3e-07 32.5 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Hexapep PF00132.24 AAZ33438.1 - 0.0021 17.7 23.0 0.39 10.5 0.0 8.2 8 1 0 8 8 8 1 Bacterial transferase hexapeptide (six repeats) PP-binding PF00550.25 AAZ33438.1 - 0.0059 16.9 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep_2 PF14602.6 AAZ33438.1 - 1.7 8.5 18.4 3 7.7 3.4 5.1 6 0 0 6 6 6 0 Hexapeptide repeat of succinyl-transferase Thiolase_N PF00108.23 AAZ33439.1 - 1.2e-77 260.8 0.5 1.6e-77 260.4 0.5 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 AAZ33439.1 - 3.6e-43 146.1 0.6 7.7e-43 145.1 0.6 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 AAZ33439.1 - 1.6e-06 27.9 0.8 3.9e-06 26.6 0.2 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain CitMHS PF03600.16 AAZ33440.1 - 0.036 13.3 0.2 0.054 12.7 0.2 1.3 1 1 0 1 1 1 0 Citrate transporter CesT PF05932.13 AAZ33441.1 - 8.1e-26 90.5 0.1 9.1e-26 90.3 0.1 1.0 1 0 0 1 1 1 1 Tir chaperone protein (CesT) family Sigma70_r4_2 PF08281.12 AAZ33442.1 - 5.7e-17 61.1 1.3 9.6e-17 60.4 0.5 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 AAZ33442.1 - 1.4e-11 44.0 1.1 3e-11 42.9 1.1 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 AAZ33442.1 - 2.6e-10 39.7 0.2 8.9e-10 37.9 0.1 2.0 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_23 PF13384.6 AAZ33442.1 - 7.3e-06 25.6 0.1 1.6e-05 24.6 0.1 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_10 PF04967.12 AAZ33442.1 - 0.00023 20.9 0.1 0.084 12.7 0.0 2.3 2 0 0 2 2 2 1 HTH DNA binding domain Sigma70_ECF PF07638.11 AAZ33442.1 - 0.00034 20.6 0.1 0.00063 19.7 0.1 1.5 1 1 0 1 1 1 1 ECF sigma factor HTH_24 PF13412.6 AAZ33442.1 - 0.00042 19.8 0.0 0.00075 19.0 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_31 PF13560.6 AAZ33442.1 - 0.0022 18.3 4.6 0.15 12.4 4.6 3.0 1 1 0 1 1 1 1 Helix-turn-helix domain Sigma70_r3 PF04539.16 AAZ33442.1 - 0.0058 16.7 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 Sigma-70 region 3 GerE PF00196.19 AAZ33442.1 - 0.0062 16.1 0.0 0.081 12.5 0.0 2.1 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family HTH_11 PF08279.12 AAZ33442.1 - 0.0081 16.1 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 HTH domain MarR_2 PF12802.7 AAZ33442.1 - 0.014 15.2 0.2 0.052 13.4 0.1 2.0 2 0 0 2 2 2 0 MarR family MerR PF00376.23 AAZ33442.1 - 0.017 14.9 0.0 0.044 13.6 0.0 1.6 1 0 0 1 1 1 0 MerR family regulatory protein HTH_5 PF01022.20 AAZ33442.1 - 0.029 14.2 0.0 0.066 13.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family DUF2236 PF09995.9 AAZ33442.1 - 0.034 14.3 1.1 0.068 13.4 1.1 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2236) HTH_40 PF14493.6 AAZ33442.1 - 0.035 14.5 0.0 0.097 13.1 0.0 1.7 1 1 1 2 2 2 0 Helix-turn-helix domain TnsD PF15978.5 AAZ33442.1 - 0.036 13.1 0.1 0.22 10.5 0.0 1.9 2 0 0 2 2 2 0 Tn7-like transposition protein D HTH_3 PF01381.22 AAZ33442.1 - 0.038 14.1 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix TetR_N PF00440.23 AAZ33442.1 - 0.04 13.7 0.1 2.4 8.0 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family FaeA PF04703.12 AAZ33442.1 - 0.064 13.6 0.1 0.11 12.8 0.1 1.4 1 0 0 1 1 1 0 FaeA-like protein HTH_29 PF13551.6 AAZ33442.1 - 0.089 12.8 0.1 0.58 10.2 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_IclR PF09339.10 AAZ33442.1 - 0.095 12.5 0.1 0.21 11.4 0.1 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain Response_reg PF00072.24 AAZ33443.1 - 1.2e-20 73.7 0.0 2.2e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AAZ33443.1 - 4.5e-18 64.5 0.1 6.6e-18 64.0 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AAZ33443.1 - 6.9e-08 32.1 0.3 2.2e-07 30.4 0.1 2.0 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAZ33443.1 - 0.0015 18.0 0.0 0.0041 16.6 0.0 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 AAZ33443.1 - 0.0037 17.2 0.0 0.0051 16.7 0.0 1.2 1 0 0 1 1 1 1 ECF sigma factor HTH_23 PF13384.6 AAZ33443.1 - 0.004 16.9 0.2 0.023 14.5 0.0 2.3 2 1 1 3 3 3 1 Homeodomain-like domain DUF2089 PF09862.9 AAZ33443.1 - 0.012 15.6 0.0 0.019 15.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) HTH_40 PF14493.6 AAZ33443.1 - 0.017 15.6 0.1 0.088 13.3 0.1 2.1 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_11 PF08279.12 AAZ33443.1 - 0.074 13.0 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 HTH domain HTH_6 PF01418.17 AAZ33443.1 - 0.13 12.2 1.7 4.5 7.3 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain, rpiR family HTH_7 PF02796.15 AAZ33443.1 - 0.15 12.2 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase FixP_N PF14715.6 AAZ33444.1 - 5.9e-24 83.5 2.9 5.9e-24 83.5 2.9 2.0 2 0 0 2 2 2 1 N-terminal domain of cytochrome oxidase-cbb3, FixP Cytochrome_CBB3 PF13442.6 AAZ33444.1 - 7.1e-24 83.9 0.2 1.6e-12 47.6 0.0 2.3 2 0 0 2 2 2 2 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AAZ33444.1 - 3e-16 60.3 0.1 3.1e-07 31.5 0.0 3.2 2 1 0 2 2 2 2 Cytochrome c Cytochrom_C550 PF14495.6 AAZ33444.1 - 0.0026 17.5 0.4 0.71 9.6 0.0 3.0 2 1 1 3 3 3 1 Cytochrome c-550 domain Paired_CXXCH_1 PF09699.10 AAZ33444.1 - 0.086 12.6 0.3 3.6 7.4 0.0 2.3 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) Ribosomal_L11_N PF03946.14 AAZ33444.1 - 0.18 11.7 0.1 0.35 10.7 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L11, N-terminal domain PSCyt1 PF07635.11 AAZ33444.1 - 0.25 12.0 1.0 24 5.6 0.2 2.7 2 1 0 2 2 2 0 Planctomycete cytochrome C HAD_2 PF13419.6 AAZ33446.1 - 5.1e-10 39.7 0.0 8.3e-10 39.0 0.0 1.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAZ33446.1 - 2.2e-08 34.7 0.0 4.3e-05 23.9 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 AAZ33446.1 - 2.5e-08 34.5 0.3 3.6e-08 34.0 0.3 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.18 AAZ33446.1 - 0.00068 19.4 0.0 0.0021 17.9 0.0 1.7 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase_6 PF13344.6 AAZ33446.1 - 0.0012 18.9 1.5 0.0094 16.1 1.5 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase MdcG PF10620.9 AAZ33447.1 - 1.5e-51 175.0 6.6 1.7e-51 174.9 6.6 1.0 1 0 0 1 1 1 1 Phosphoribosyl-dephospho-CoA transferase MdcG LysR_substrate PF03466.20 AAZ33448.1 - 8.8e-41 139.6 0.3 1.3e-40 139.0 0.3 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ33448.1 - 4.5e-23 81.0 0.5 9.9e-23 79.9 0.5 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_24 PF13412.6 AAZ33448.1 - 0.11 12.1 0.0 0.28 10.8 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding CLP_protease PF00574.23 AAZ33449.1 - 2.2e-87 291.7 0.0 2.7e-87 291.4 0.0 1.1 1 0 0 1 1 1 1 Clp protease Aldedh PF00171.22 AAZ33450.1 - 1.7e-142 475.2 0.7 2.1e-142 474.9 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 AAZ33450.1 - 0.0019 17.3 0.1 0.0041 16.2 0.1 1.5 1 1 1 2 2 2 1 Acyl-CoA reductase (LuxC) PLDc_2 PF13091.6 AAZ33451.1 - 8.8e-14 51.5 0.0 6.4e-08 32.6 0.0 3.3 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 AAZ33451.1 - 1.5e-06 28.1 1.1 0.03 14.5 0.3 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif DHQ_synthase PF01761.20 AAZ33452.1 - 1.2e-106 355.7 0.0 1.4e-106 355.5 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 AAZ33452.1 - 3.8e-12 46.4 0.3 5.6e-11 42.6 0.3 2.0 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 AAZ33452.1 - 1.6e-06 27.2 0.5 3.1e-06 26.2 0.1 1.6 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase TauD PF02668.16 AAZ33453.1 - 2e-49 168.8 0.0 2.5e-49 168.5 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Cytochrom_C_asm PF01578.20 AAZ33454.1 - 5.4e-38 130.9 20.5 7.7e-38 130.4 20.5 1.2 1 0 0 1 1 1 1 Cytochrome C assembly protein HlyD_3 PF13437.6 AAZ33456.1 - 4.9e-15 56.1 0.1 4e-10 40.4 0.0 2.7 2 1 0 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 AAZ33456.1 - 8.4e-10 38.2 0.7 0.00047 19.4 0.0 2.7 1 1 0 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD PF00529.20 AAZ33456.1 - 8.9e-07 28.7 0.0 1.1e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl_2 PF13533.6 AAZ33456.1 - 4.3e-06 26.4 0.8 0.00014 21.6 0.1 3.2 3 0 0 3 3 3 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AAZ33456.1 - 0.00028 20.7 0.0 0.22 11.4 0.0 2.5 2 0 0 2 2 2 2 Biotin-requiring enzyme ARA70 PF12489.8 AAZ33457.1 - 0.16 12.2 0.0 0.2 11.9 0.0 1.2 1 0 0 1 1 1 0 Nuclear coactivator TonB_C PF03544.14 AAZ33459.1 - 1.5e-23 83.0 0.0 2.5e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 Gram-negative bacterial TonB protein C-terminal TonB_2 PF13103.6 AAZ33459.1 - 0.00086 19.5 0.0 0.00086 19.5 0.0 2.5 3 0 0 3 3 3 1 TonB C terminal Gly-rich_Ago1 PF12764.7 AAZ33460.1 - 0.047 14.5 0.0 0.071 13.9 0.0 1.2 1 0 0 1 1 1 0 Glycine-rich region of argonaut CN_hydrolase PF00795.22 AAZ33460.1 - 0.14 11.5 0.1 0.19 11.1 0.1 1.1 1 0 0 1 1 1 0 Carbon-nitrogen hydrolase Fimbrial_CS1 PF04449.12 AAZ33461.1 - 4.6e-29 101.3 0.7 5.4e-29 101.1 0.7 1.0 1 0 0 1 1 1 1 CS1 type fimbrial major subunit SNF2_N PF00176.23 AAZ33462.1 - 3.5e-62 210.1 0.2 1e-61 208.6 0.2 1.5 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 AAZ33462.1 - 5.4e-18 65.4 0.0 1.3e-17 64.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 AAZ33462.1 - 3.8e-05 23.8 0.0 8.1e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWIM PF04434.17 AAZ33462.1 - 0.001 18.7 2.9 0.0024 17.5 2.9 1.6 1 0 0 1 1 1 1 SWIM zinc finger SNF2_assoc PF08455.10 AAZ33462.1 - 0.0061 15.6 0.0 0.0098 15.0 0.0 1.2 1 0 0 1 1 1 1 Bacterial SNF2 helicase associated Aldedh PF00171.22 AAZ33463.1 - 2.2e-159 530.9 1.4 2.5e-159 530.7 1.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Sulphotransf PF09037.10 AAZ33463.1 - 0.12 11.9 0.2 0.2 11.2 0.2 1.3 1 0 0 1 1 1 0 Stf0 sulphotransferase KfrA_N PF11740.8 AAZ33463.1 - 0.5 11.1 11.0 0.35 11.6 0.2 3.3 3 1 0 3 3 3 0 Plasmid replication region DNA-binding N-term Epimerase PF01370.21 AAZ33465.1 - 1.5e-15 57.3 0.0 3.4e-15 56.2 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 AAZ33465.1 - 5.3e-14 51.9 0.0 7.4e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 AAZ33465.1 - 2.4e-09 36.7 0.1 4.1e-08 32.7 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 AAZ33465.1 - 1.1e-06 28.3 0.0 1.5e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 AAZ33465.1 - 0.00055 19.9 0.0 0.00091 19.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Endonuc_subdom PF09062.10 AAZ33465.1 - 0.094 13.6 0.1 0.22 12.4 0.0 1.7 2 0 0 2 2 2 0 PI-PfuI Endonuclease subdomain NmrA PF05368.13 AAZ33465.1 - 0.14 11.7 0.0 2.1 7.9 0.1 2.1 2 0 0 2 2 2 0 NmrA-like family GSK-3_bind PF05350.12 AAZ33465.1 - 0.22 10.8 0.5 0.59 9.4 0.2 1.8 2 0 0 2 2 2 0 Glycogen synthase kinase-3 binding Sigma54_activat PF00158.26 AAZ33467.1 - 9.5e-63 210.9 0.0 2.4e-62 209.6 0.0 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain Response_reg PF00072.24 AAZ33467.1 - 4.2e-28 97.8 0.1 7.8e-28 96.9 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Sigma54_activ_2 PF14532.6 AAZ33467.1 - 1e-15 58.0 0.0 8.4e-15 55.1 0.0 2.4 2 1 0 2 2 2 1 Sigma-54 interaction domain HTH_8 PF02954.19 AAZ33467.1 - 6.3e-09 35.5 0.1 1.7e-08 34.1 0.1 1.8 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 AAZ33467.1 - 4.8e-07 29.9 0.0 1.4e-05 25.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA PF00004.29 AAZ33467.1 - 1.1e-06 29.1 0.0 2.9e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 AAZ33467.1 - 0.00011 21.6 0.1 0.0026 17.2 0.1 2.3 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 AAZ33467.1 - 0.0016 18.5 0.0 0.012 15.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 AAZ33467.1 - 0.0022 18.3 0.0 0.0063 16.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 AAZ33467.1 - 0.0024 17.6 0.0 0.0048 16.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein MCM PF00493.23 AAZ33467.1 - 0.0094 15.1 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain HTH_29 PF13551.6 AAZ33467.1 - 0.023 14.7 0.3 0.19 11.8 0.0 2.5 2 0 0 2 2 2 0 Winged helix-turn helix AAA_16 PF13191.6 AAZ33467.1 - 0.046 14.1 0.1 0.11 12.9 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain HTH_23 PF13384.6 AAZ33467.1 - 0.052 13.4 0.0 0.19 11.6 0.0 2.1 1 0 0 1 1 1 0 Homeodomain-like domain DUF1858 PF08984.11 AAZ33467.1 - 0.079 13.1 0.0 0.33 11.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1858) HTH_17 PF12728.7 AAZ33467.1 - 0.14 12.4 0.1 0.41 10.9 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain ABC_tran PF00005.27 AAZ33468.1 - 4.8e-26 91.9 0.0 6.8e-26 91.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 AAZ33468.1 - 1.9e-20 73.2 0.0 3.3e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 AAZ33468.1 - 7.1e-05 22.8 3.2 7.1e-05 22.7 0.2 1.9 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AIG1 PF04548.16 AAZ33468.1 - 0.061 12.6 0.3 0.12 11.7 0.3 1.4 1 0 0 1 1 1 0 AIG1 family AAA_22 PF13401.6 AAZ33468.1 - 0.14 12.4 0.6 4.3 7.6 0.1 2.2 2 0 0 2 2 2 0 AAA domain DUF1534 PF07551.11 AAZ33469.1 - 4.2e-20 71.2 36.9 8.2e-06 25.5 0.7 6.0 6 0 0 6 6 6 5 Protein of unknown function (DUF1534) Asp_decarbox PF02261.16 AAZ33469.1 - 0.017 15.0 0.0 8.9 6.3 0.0 2.3 2 0 0 2 2 2 0 Aspartate decarboxylase zinc_ribbon_9 PF14369.6 AAZ33469.1 - 0.019 15.2 4.0 4.1 7.8 0.3 2.7 2 0 0 2 2 2 0 zinc-ribbon Tat PF00539.18 AAZ33469.1 - 4.3 7.6 10.7 12 6.2 1.6 2.6 2 0 0 2 2 2 0 Transactivating regulatory protein (Tat) Methyltransf_23 PF13489.6 AAZ33470.1 - 1.7e-12 47.4 0.0 2.3e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAZ33470.1 - 1.7e-11 44.6 0.1 4.1e-11 43.4 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAZ33470.1 - 1.3e-07 31.6 0.0 2.1e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAZ33470.1 - 1.2e-06 29.2 0.0 2.6e-06 28.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAZ33470.1 - 3.2e-06 27.8 0.0 5.3e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AAZ33470.1 - 0.00013 21.4 0.0 0.00025 20.5 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 AAZ33470.1 - 0.012 15.3 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW zf-C2H2_4 PF13894.6 AAZ33470.1 - 0.078 13.9 1.0 0.078 13.9 1.0 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger NodS PF05401.11 AAZ33470.1 - 0.18 11.4 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Zn-C2H2_12 PF18112.1 AAZ33470.1 - 5.6 7.5 9.5 0.66 10.5 3.7 2.4 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Phage_integrase PF00589.22 AAZ33471.1 - 3.5e-18 66.0 0.0 2.4e-17 63.2 0.0 2.3 1 1 0 1 1 1 1 Phage integrase family Arm-DNA-bind_4 PF14657.6 AAZ33471.1 - 0.00065 19.4 0.3 0.0014 18.3 0.3 1.6 1 1 0 1 1 1 1 Arm DNA-binding domain DUF2188 PF09954.9 AAZ33471.1 - 0.038 14.1 0.1 0.17 12.0 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) LysR_substrate PF03466.20 AAZ33472.1 - 1.3e-45 155.3 0.7 1.7e-45 154.9 0.7 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ33472.1 - 6.1e-18 64.5 1.9 1.3e-17 63.5 1.9 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AAZ33472.1 - 0.00017 21.3 0.2 0.00047 19.9 0.2 1.8 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_28 PF13518.6 AAZ33472.1 - 0.0092 16.1 0.0 0.024 14.8 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_8 PF02954.19 AAZ33472.1 - 0.025 14.3 0.0 0.079 12.8 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family MarR_2 PF12802.7 AAZ33472.1 - 0.058 13.3 0.1 0.3 11.0 0.0 2.2 2 0 0 2 2 2 0 MarR family DUF2089 PF09862.9 AAZ33472.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) Abhydrolase_1 PF00561.20 AAZ33473.1 - 2.4e-18 66.7 0.0 8.9e-14 51.7 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AAZ33473.1 - 2.5e-16 59.7 0.0 5e-16 58.7 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AAZ33473.1 - 9.3e-14 52.6 1.1 1.2e-13 52.2 1.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 AAZ33473.1 - 0.0049 17.0 0.0 0.018 15.2 0.0 1.9 2 0 0 2 2 2 1 TAP-like protein FSH1 PF03959.13 AAZ33473.1 - 0.0089 15.7 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Ndr PF03096.14 AAZ33473.1 - 0.0094 14.7 0.0 0.011 14.4 0.0 1.1 1 0 0 1 1 1 1 Ndr family NTP_transf_3 PF12804.7 AAZ33474.1 - 2.6e-34 118.9 1.8 4e-34 118.3 1.8 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 AAZ33474.1 - 0.012 15.4 0.1 0.016 15.0 0.1 1.2 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DUF2064 PF09837.9 AAZ33474.1 - 0.08 12.8 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2064) M20_dimer PF07687.14 AAZ33475.1 - 8.1e-23 80.4 0.0 1.2e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 AAZ33475.1 - 5.5e-15 55.6 0.0 7.7e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 AFG1_ATPase PF03969.16 AAZ33476.1 - 8.9e-160 531.5 0.4 1e-159 531.3 0.4 1.0 1 0 0 1 1 1 1 AFG1-like ATPase WhiA_N PF10298.9 AAZ33476.1 - 0.1 12.7 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 WhiA N-terminal LAGLIDADG-like domain Secretin PF00263.21 AAZ33477.1 - 7.4e-45 152.6 0.0 1.3e-44 151.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial type II and III secretion system protein T2SS-T3SS_pil_N PF13629.6 AAZ33477.1 - 1.2e-19 69.8 0.2 3.5e-19 68.3 0.2 1.9 1 0 0 1 1 1 1 Pilus formation protein N terminal region Hist_deacetyl PF00850.19 AAZ33478.1 - 5.7e-46 157.4 0.0 1e-45 156.5 0.0 1.4 1 1 0 1 1 1 1 Histone deacetylase domain BPD_transp_2 PF02653.16 AAZ33479.1 - 5.4e-46 156.9 41.6 5.4e-46 156.9 41.6 1.4 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component Trp_syntA PF00290.20 AAZ33480.1 - 3.2e-99 331.0 0.2 3.6e-99 330.8 0.2 1.0 1 0 0 1 1 1 1 Tryptophan synthase alpha chain His_biosynth PF00977.21 AAZ33480.1 - 2.6e-06 27.1 0.2 7.1e-06 25.6 0.1 1.7 2 0 0 2 2 2 1 Histidine biosynthesis protein PcrB PF01884.17 AAZ33480.1 - 2.3e-05 24.0 0.1 4.5e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 PcrB family ThiG PF05690.14 AAZ33480.1 - 0.012 14.9 0.1 0.021 14.1 0.1 1.4 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG PEP_mutase PF13714.6 AAZ33480.1 - 0.03 13.8 0.2 0.25 10.8 0.2 2.1 2 0 0 2 2 2 0 Phosphoenolpyruvate phosphomutase PA PF02225.22 AAZ33480.1 - 0.051 13.6 0.1 0.44 10.6 0.0 2.4 3 0 0 3 3 3 0 PA domain DUF3416 PF11896.8 AAZ33481.1 - 2.8e-51 174.4 0.1 3.8e-51 173.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3416) Alpha-amylase PF00128.24 AAZ33481.1 - 2.4e-07 30.7 0.0 1.4e-06 28.2 0.0 2.1 1 1 0 1 1 1 1 Alpha amylase, catalytic domain GHL6 PF14871.6 AAZ33481.1 - 0.00056 20.1 0.0 0.001 19.2 0.0 1.3 1 0 0 1 1 1 1 Hypothetical glycosyl hydrolase 6 hDGE_amylase PF14701.6 AAZ33481.1 - 0.079 12.0 0.0 2.2 7.3 0.0 2.4 2 1 0 2 2 2 0 Glycogen debranching enzyme, glucanotransferase domain Ribosomal_S9 PF00380.19 AAZ33482.1 - 1.1e-46 158.3 0.8 1.2e-46 158.1 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 TetR_N PF00440.23 AAZ33483.1 - 1e-12 47.7 0.1 1.8e-12 46.9 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family DUF4096 PF13340.6 AAZ33484.1 - 5.8e-25 87.3 0.4 1.5e-24 86.0 0.4 1.8 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1 PF01609.21 AAZ33484.1 - 3.2e-14 53.1 0.0 5.7e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AAZ33484.1 - 7.2e-10 39.1 0.2 2.1e-09 37.6 0.2 1.9 1 0 0 1 1 1 1 Transposase DDE domain HTH_Tnp_Tc3_2 PF01498.18 AAZ33484.1 - 0.061 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Transposase TerC PF03741.16 AAZ33485.1 - 4.2e-46 156.9 13.4 6.6e-46 156.3 13.4 1.3 1 0 0 1 1 1 1 Integral membrane protein TerC family CorC_HlyC PF03471.17 AAZ33485.1 - 1.3e-16 60.4 0.0 2.6e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 Transporter associated domain CBS PF00571.28 AAZ33485.1 - 2.4e-12 47.1 0.1 7.1e-08 32.8 0.0 2.7 2 0 0 2 2 2 2 CBS domain DUF475 PF04332.15 AAZ33485.1 - 0.00078 19.3 2.9 0.0013 18.6 2.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF475) DUF751 PF05421.11 AAZ33485.1 - 1.8 9.3 8.5 12 6.7 0.5 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF751) DUF883 PF05957.13 AAZ33486.1 - 9.1e-31 106.3 3.1 1.1e-30 106.1 3.1 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) HALZ PF02183.18 AAZ33486.1 - 0.021 15.0 1.9 0.28 11.5 0.1 2.2 1 1 1 2 2 2 0 Homeobox associated leucine zipper Apolipoprotein PF01442.18 AAZ33486.1 - 0.034 14.0 6.8 0.038 13.8 6.8 1.0 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain YtxH PF12732.7 AAZ33486.1 - 2.4 8.8 5.6 1.4 9.5 0.6 2.4 2 1 1 3 3 3 0 YtxH-like protein BPL_LplA_LipB PF03099.19 AAZ33487.1 - 6.9e-06 26.0 0.0 1.7e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Trypsin_2 PF13365.6 AAZ33488.1 - 1.2e-34 120.3 0.1 2.3e-34 119.5 0.1 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 AAZ33488.1 - 3.2e-29 101.1 2.7 5e-17 62.0 0.1 2.8 3 0 0 3 3 3 2 PDZ domain PDZ_6 PF17820.1 AAZ33488.1 - 1.2e-21 76.2 0.9 8.4e-11 41.6 0.3 2.8 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 AAZ33488.1 - 8.2e-17 61.3 2.0 1.4e-09 38.1 0.2 2.7 2 0 0 2 2 2 2 PDZ domain Trypsin PF00089.26 AAZ33488.1 - 4.9e-14 52.7 0.0 9.7e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.6 AAZ33488.1 - 1.4e-05 24.9 0.9 0.011 15.7 0.1 2.9 3 0 0 3 3 3 2 Tricorn protease PDZ domain PDZ_1 PF12812.7 AAZ33488.1 - 4.9e-05 23.3 0.1 0.0013 18.7 0.0 3.1 3 1 1 4 4 4 1 PDZ-like domain Peptidase_S46 PF10459.9 AAZ33488.1 - 5.4e-05 22.0 0.4 0.026 13.2 0.3 2.1 2 0 0 2 2 2 2 Peptidase S46 T2SSI PF02501.17 AAZ33489.1 - 5.8e-13 48.8 0.1 1.4e-12 47.6 0.0 1.6 2 0 0 2 2 2 1 Type II secretion system (T2SS), protein I N_methyl PF07963.12 AAZ33489.1 - 6.2e-11 41.4 0.3 1.4e-10 40.2 0.3 1.7 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif AhpC-TSA PF00578.21 AAZ33490.1 - 1.3e-30 105.8 0.0 2e-30 105.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AAZ33490.1 - 1e-14 54.4 0.0 1.4e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 AAZ33490.1 - 7.6e-11 41.7 0.0 1.4e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin ASH PF15780.5 AAZ33490.1 - 0.099 12.9 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin AhpC-TSA_2 PF13911.6 AAZ33490.1 - 0.12 12.6 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme MFS_1 PF07690.16 AAZ33492.1 - 3.3e-12 46.0 41.9 3.3e-12 46.0 41.9 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily IncD PF17628.2 AAZ33492.1 - 0.061 13.1 0.2 0.061 13.1 0.2 2.7 3 0 0 3 3 3 0 Inclusion membrane protein D Ald_Xan_dh_C2 PF02738.18 AAZ33493.1 - 2.6e-202 673.1 4.5 3.4e-202 672.8 4.5 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 AAZ33493.1 - 1.2e-21 77.1 0.0 2.5e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain LysR_substrate PF03466.20 AAZ33494.1 - 1.4e-45 155.3 0.6 1.7e-45 154.9 0.6 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ33494.1 - 6.9e-18 64.4 0.2 6.9e-18 64.4 0.2 1.7 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 AAZ33494.1 - 0.014 15.2 0.0 0.087 12.7 0.0 2.2 2 0 0 2 2 2 0 MarR family DUF4912 PF16258.5 AAZ33494.1 - 0.16 12.2 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4912) Fe_dep_repress PF01325.19 AAZ33494.1 - 0.18 12.0 0.2 0.52 10.6 0.1 1.8 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain Hydrolase_3 PF08282.12 AAZ33495.1 - 5.9e-10 39.3 0.0 6.5e-07 29.4 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAZ33495.1 - 7.8e-08 32.9 0.7 0.00078 19.8 0.0 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 AAZ33495.1 - 0.00012 22.2 0.7 0.0067 16.5 0.0 2.7 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 AAZ33495.1 - 0.0042 17.5 1.6 0.14 12.6 0.0 2.6 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Pribosyltran_N PF13793.6 AAZ33496.1 - 3.4e-50 168.9 0.3 3.5e-48 162.3 0.0 2.4 2 1 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 AAZ33496.1 - 4e-35 121.5 1.8 7.7e-35 120.6 0.6 2.0 2 1 1 3 3 3 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 AAZ33496.1 - 5.1e-20 71.6 2.1 6.2e-19 68.1 1.0 2.3 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 AAZ33496.1 - 0.0022 17.5 0.1 0.0037 16.7 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Tad PF13400.6 AAZ33497.1 - 4.7e-06 26.8 3.2 4.7e-06 26.8 3.2 2.8 2 0 0 2 2 2 1 Putative Flp pilus-assembly TadE/G-like ImpA_N PF06812.12 AAZ33498.1 - 7.4e-28 97.0 0.8 1.5e-27 96.0 0.5 1.7 2 0 0 2 2 2 1 ImpA, N-terminal, type VI secretion system GNAT_acetyltr_2 PF13718.6 AAZ33498.1 - 0.068 12.6 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Nitroreductase PF00881.24 AAZ33499.1 - 5e-27 95.0 0.0 6.2e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 AAZ33499.1 - 0.018 14.6 0.0 1.3 8.6 0.0 2.4 2 1 0 2 2 2 0 Putative TM nitroreductase Cupin_2 PF07883.11 AAZ33500.1 - 9.6e-08 31.6 0.0 6.4e-07 29.0 0.0 2.0 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.12 AAZ33500.1 - 0.048 13.4 0.0 0.079 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) TnpB_IS66 PF05717.13 AAZ33501.1 - 1.3e-27 95.7 0.0 1.4e-27 95.5 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein Peptidase_M16 PF00675.20 AAZ33502.1 - 2.1e-32 112.2 0.0 3.8e-31 108.1 0.0 2.6 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 AAZ33502.1 - 2.3e-10 40.8 0.0 2.6e-05 24.3 0.0 2.9 2 0 0 2 2 2 2 Peptidase M16 inactive domain CHAD PF05235.14 AAZ33502.1 - 0.0064 16.5 0.7 0.025 14.6 0.0 2.3 3 0 0 3 3 3 1 CHAD domain Cons_hypoth95 PF03602.15 AAZ33503.1 - 1.8e-57 193.9 0.0 2.1e-57 193.7 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 AAZ33503.1 - 1.7e-09 37.4 0.0 2.3e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 AAZ33503.1 - 4.4e-07 29.8 0.0 5.3e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAZ33503.1 - 2.4e-05 24.9 0.0 3.2e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 AAZ33503.1 - 0.00024 20.6 0.0 0.00028 20.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltr_RsmB-F PF01189.17 AAZ33503.1 - 0.00052 19.7 0.0 0.00068 19.3 0.0 1.1 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F MethyltransfD12 PF02086.15 AAZ33503.1 - 0.0097 15.6 0.0 0.64 9.7 0.0 2.1 1 1 1 2 2 2 2 D12 class N6 adenine-specific DNA methyltransferase TRM PF02005.16 AAZ33503.1 - 0.052 12.7 0.0 0.058 12.6 0.0 1.0 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase N6_Mtase PF02384.16 AAZ33503.1 - 0.23 10.7 0.0 0.49 9.6 0.0 1.4 1 1 0 1 1 1 0 N-6 DNA Methylase Methyltransf_15 PF09445.10 AAZ33503.1 - 0.26 10.9 0.0 0.34 10.5 0.0 1.1 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Inositol_P PF00459.25 AAZ33504.1 - 2.4e-41 142.0 0.0 2.8e-41 141.8 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Citrate_synt PF00285.21 AAZ33505.1 - 2.5e-133 444.6 0.0 3e-133 444.4 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain ABC_tran PF00005.27 AAZ33507.1 - 3.3e-33 115.1 0.0 4.5e-33 114.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AAZ33507.1 - 7.7e-08 32.0 0.0 6.4e-05 22.5 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AAZ33507.1 - 2.8e-07 30.7 1.8 0.0026 17.6 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AAZ33507.1 - 0.0002 21.0 0.1 0.00038 20.2 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AAZ33507.1 - 0.00077 19.4 0.2 0.0015 18.4 0.2 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 AAZ33507.1 - 0.0014 19.0 0.8 0.0042 17.5 0.8 1.7 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 AAZ33507.1 - 0.0017 18.4 0.2 0.0082 16.2 0.1 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 AAZ33507.1 - 0.01 15.9 0.7 0.042 13.9 0.5 1.8 2 0 0 2 2 2 0 Dynamin family SbcCD_C PF13558.6 AAZ33507.1 - 0.012 15.8 0.0 0.2 11.9 0.0 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 AAZ33507.1 - 0.016 15.4 0.8 0.16 12.1 0.8 2.1 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 AAZ33507.1 - 0.022 14.7 0.5 0.47 10.3 0.1 2.2 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 AAZ33507.1 - 0.022 15.0 0.1 0.05 13.8 0.1 1.6 2 0 0 2 2 1 0 AAA domain DUF87 PF01935.17 AAZ33507.1 - 0.028 14.5 0.0 0.047 13.8 0.0 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain NTPase_1 PF03266.15 AAZ33507.1 - 0.035 14.0 0.1 8.7 6.2 0.0 2.1 2 0 0 2 2 2 0 NTPase FtsK_SpoIIIE PF01580.18 AAZ33507.1 - 0.038 13.3 0.1 0.062 12.7 0.1 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_13 PF13166.6 AAZ33507.1 - 0.066 11.8 0.0 1 7.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 AAZ33507.1 - 0.083 13.4 0.0 0.12 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AAZ33507.1 - 0.11 12.8 0.4 0.46 10.8 0.1 2.0 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 AAZ33507.1 - 0.15 11.3 0.0 0.35 10.1 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.6 AAZ33507.1 - 0.22 11.2 0.0 0.38 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain CPSase_sm_chain PF00988.22 AAZ33508.1 - 3.2e-52 175.7 0.0 4.8e-52 175.2 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 AAZ33508.1 - 5.2e-45 153.6 0.0 7.6e-45 153.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AAZ33508.1 - 2.2e-07 30.9 0.2 4.7e-06 26.5 0.2 2.5 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 AAZ33508.1 - 0.013 15.3 0.0 0.032 14.0 0.0 1.6 1 1 0 1 1 1 0 DJ-1/PfpI family RraB PF06877.11 AAZ33509.1 - 5.8e-22 78.3 0.0 6.6e-22 78.2 0.0 1.0 1 0 0 1 1 1 1 Regulator of ribonuclease activity B Lig_C PF18330.1 AAZ33509.1 - 0.035 14.1 0.0 0.051 13.6 0.0 1.2 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region Fer2 PF00111.27 AAZ33510.1 - 9e-14 51.2 4.0 1.2e-13 50.8 4.0 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Rhodanese PF00581.20 AAZ33511.1 - 4.8e-41 139.6 0.0 3.8e-10 40.2 0.0 4.2 4 0 0 4 4 4 4 Rhodanese-like domain NMT1 PF09084.11 AAZ33512.1 - 6.6e-16 58.9 0.0 6.9e-15 55.6 0.0 2.2 2 0 0 2 2 2 1 NMT1/THI5 like NMT1_2 PF13379.6 AAZ33512.1 - 1.8e-13 50.8 0.1 2.7e-13 50.2 0.1 1.3 1 0 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.7 AAZ33512.1 - 2e-11 44.0 0.4 2.8e-11 43.5 0.4 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 AAZ33512.1 - 1.8e-07 30.8 0.0 9.3e-07 28.5 0.0 2.1 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1_3 PF16868.5 AAZ33512.1 - 4.5e-06 26.3 0.1 2.1e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 NMT1-like family Lipoprotein_9 PF03180.14 AAZ33512.1 - 0.018 14.2 0.0 0.028 13.6 0.0 1.2 1 0 0 1 1 1 0 NLPA lipoprotein Sulfate_transp PF00916.20 AAZ33513.1 - 1.2e-41 142.7 23.3 4.1e-29 101.5 4.9 2.6 1 1 1 2 2 2 2 Sulfate permease family STAS PF01740.21 AAZ33513.1 - 3.3e-08 33.2 0.0 6.9e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 AAZ33513.1 - 5.6e-05 23.4 0.5 0.00013 22.3 0.5 1.6 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 AAZ33513.1 - 9e-05 22.8 5.0 9e-05 22.8 5.0 3.7 4 0 0 4 4 4 1 Molybdate transporter of MFS superfamily DIOX_N PF14226.6 AAZ33514.1 - 2.6e-30 105.6 0.0 3e-30 105.4 0.0 1.0 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Glyco_trans_1_4 PF13692.6 AAZ33515.1 - 1.7e-11 44.7 0.0 4.3e-11 43.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AAZ33515.1 - 0.00015 22.1 0.0 0.00074 19.9 0.0 2.1 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AAZ33515.1 - 0.00092 18.8 0.0 0.002 17.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Sin3a_C PF16879.5 AAZ33515.1 - 0.09 12.5 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 C-terminal domain of Sin3a protein adh_short_C2 PF13561.6 AAZ33516.1 - 5.5e-56 189.7 0.4 6.6e-56 189.5 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAZ33516.1 - 2.1e-50 170.9 0.0 2.6e-50 170.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAZ33516.1 - 5.3e-22 78.6 0.2 7.5e-22 78.1 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AAZ33516.1 - 2.4e-05 23.9 0.2 3.4e-05 23.4 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Rdx PF10262.9 AAZ33517.1 - 9.5e-33 112.2 0.0 1.1e-32 112.0 0.0 1.0 1 0 0 1 1 1 1 Rdx family HAD_2 PF13419.6 AAZ33518.1 - 1.6e-29 103.2 0.0 2e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAZ33518.1 - 8e-14 52.4 0.1 8.8e-13 49.0 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AAZ33518.1 - 3.2e-13 49.5 0.0 7.7e-13 48.3 0.0 1.6 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 AAZ33518.1 - 1.9e-09 38.2 0.3 2.5e-09 37.8 0.3 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AAZ33518.1 - 0.00072 19.4 0.1 3.5 7.3 0.1 3.0 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase DUF3530 PF12048.8 AAZ33519.1 - 1.4e-98 330.1 12.2 1.6e-98 329.9 12.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3530) LIDHydrolase PF10230.9 AAZ33519.1 - 4.7e-05 23.1 0.0 7.5e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 AAZ33519.1 - 0.00052 19.3 0.0 0.0013 18.0 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 AAZ33519.1 - 0.00073 19.3 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF3089 PF11288.8 AAZ33519.1 - 0.0012 18.5 0.1 0.0025 17.4 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3089) Ser_hydrolase PF06821.13 AAZ33519.1 - 0.0017 18.2 0.8 0.0031 17.4 0.8 1.4 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_6 PF12697.7 AAZ33519.1 - 0.0065 17.1 0.3 0.0065 17.1 0.3 2.2 1 1 1 2 2 1 1 Alpha/beta hydrolase family UPF0227 PF05728.12 AAZ33519.1 - 0.016 15.1 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_1 PF00561.20 AAZ33519.1 - 0.025 14.2 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.20 AAZ33519.1 - 0.05 13.7 1.4 0.08 13.0 0.3 1.9 2 1 1 3 3 3 0 Thioesterase domain DUF915 PF06028.11 AAZ33519.1 - 0.12 11.6 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) LCAT PF02450.15 AAZ33519.1 - 0.17 11.0 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase LysE PF01810.18 AAZ33520.1 - 9.3e-30 103.5 11.2 1.1e-29 103.3 11.2 1.0 1 0 0 1 1 1 1 LysE type translocator TerC PF03741.16 AAZ33520.1 - 0.026 14.2 0.5 0.026 14.2 0.5 2.0 2 0 0 2 2 2 0 Integral membrane protein TerC family ABC_tran PF00005.27 AAZ33521.1 - 6.9e-34 117.3 0.0 9.5e-34 116.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAZ33521.1 - 1.5e-12 47.9 0.1 6.7e-06 26.1 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAZ33521.1 - 1.2e-10 41.2 0.2 5.4e-09 35.8 0.2 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AAZ33521.1 - 1.7e-05 25.1 0.0 6.8e-05 23.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 AAZ33521.1 - 5e-05 22.3 0.0 0.08 11.7 0.0 2.1 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_23 PF13476.6 AAZ33521.1 - 5.9e-05 23.7 0.2 0.00013 22.6 0.2 1.8 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AAZ33521.1 - 6.3e-05 22.9 0.0 0.00015 21.8 0.0 1.6 2 0 0 2 2 1 1 RsgA GTPase Rad17 PF03215.15 AAZ33521.1 - 8.4e-05 22.6 0.0 0.00012 22.1 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 AAZ33521.1 - 0.00014 22.3 0.0 0.00028 21.3 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 AAZ33521.1 - 0.00018 21.3 0.1 0.029 14.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 AAZ33521.1 - 0.00025 20.7 0.0 0.00053 19.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 AAZ33521.1 - 0.00048 20.0 0.1 0.0015 18.4 0.0 1.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 AAZ33521.1 - 0.0033 17.2 0.0 0.01 15.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 AAZ33521.1 - 0.0034 17.3 0.2 0.0093 15.9 0.0 1.7 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea Adeno_IVa2 PF02456.15 AAZ33521.1 - 0.0045 15.8 0.0 0.016 14.0 0.0 1.8 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA_11 PF13086.6 AAZ33521.1 - 0.0062 16.4 0.1 0.01 15.7 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 AAZ33521.1 - 0.018 15.4 0.1 0.26 11.7 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 AAZ33521.1 - 0.02 14.5 0.0 0.084 12.4 0.0 1.9 2 1 0 2 2 2 0 AAA domain PRK PF00485.18 AAZ33521.1 - 0.022 14.5 0.0 0.053 13.3 0.0 1.7 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family TniB PF05621.11 AAZ33521.1 - 0.027 13.9 0.1 0.39 10.1 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein AAA_14 PF13173.6 AAZ33521.1 - 0.047 13.7 0.0 0.11 12.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 AAZ33521.1 - 0.056 12.8 0.2 0.17 11.2 0.0 1.8 2 0 0 2 2 2 0 KaiC NACHT PF05729.12 AAZ33521.1 - 0.062 13.2 0.0 0.22 11.4 0.0 1.9 2 0 0 2 2 2 0 NACHT domain SbcCD_C PF13558.6 AAZ33521.1 - 0.07 13.4 0.1 2.1 8.6 0.1 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit PhoH PF02562.16 AAZ33521.1 - 0.084 12.3 0.0 0.2 11.1 0.0 1.9 1 1 0 1 1 1 0 PhoH-like protein G-alpha PF00503.20 AAZ33521.1 - 0.12 11.5 0.0 0.25 10.4 0.0 1.4 1 1 0 1 1 1 0 G-protein alpha subunit AAA_5 PF07728.14 AAZ33521.1 - 0.13 12.2 0.2 0.5 10.4 0.0 2.0 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 AAZ33521.1 - 0.14 11.4 0.0 0.41 9.8 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA_28 PF13521.6 AAZ33521.1 - 0.15 12.3 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AAZ33522.1 - 3.3e-29 102.1 0.0 4.8e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAZ33522.1 - 3.8e-08 33.5 0.0 0.0023 17.8 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAZ33522.1 - 3.7e-06 26.5 0.1 5.4e-05 22.7 0.1 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 AAZ33522.1 - 0.00011 22.2 0.0 0.00021 21.2 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 AAZ33522.1 - 0.0002 21.7 0.0 0.0006 20.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAZ33522.1 - 0.0028 17.4 0.0 0.006 16.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AAZ33522.1 - 0.0038 17.6 0.0 0.0062 16.9 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.6 AAZ33522.1 - 0.0067 16.2 0.0 0.0079 15.9 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 AAZ33522.1 - 0.008 16.7 0.0 0.016 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 AAZ33522.1 - 0.0088 15.6 0.0 0.019 14.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AAZ33522.1 - 0.024 14.8 0.0 0.041 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 AAZ33522.1 - 0.032 14.1 0.0 0.061 13.3 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain TniB PF05621.11 AAZ33522.1 - 0.041 13.3 0.1 0.87 9.0 0.0 2.4 2 1 1 3 3 3 0 Bacterial TniB protein NB-ARC PF00931.22 AAZ33522.1 - 0.069 12.3 0.0 0.083 12.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Adeno_IVa2 PF02456.15 AAZ33522.1 - 0.11 11.3 0.0 0.45 9.3 0.0 1.8 2 0 0 2 2 2 0 Adenovirus IVa2 protein Spermine_synt_N PF17284.2 AAZ33522.1 - 0.12 12.3 0.3 0.28 11.1 0.3 1.6 1 0 0 1 1 1 0 Spermidine synthase tetramerisation domain AAA_5 PF07728.14 AAZ33522.1 - 0.14 12.1 0.0 0.97 9.4 0.0 2.2 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 AAZ33522.1 - 0.16 12.4 0.0 1.1 9.7 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) YchF-GTPase_C PF06071.13 AAZ33523.1 - 3.4e-41 139.3 0.4 7.7e-41 138.2 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 AAZ33523.1 - 2.1e-22 79.4 0.0 6.3e-22 77.8 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AAZ33523.1 - 1.6e-07 31.0 0.0 4.3e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 AAZ33523.1 - 0.036 14.1 0.6 0.32 11.1 0.3 2.5 2 1 0 2 2 2 0 TGS domain RNA_helicase PF00910.22 AAZ33523.1 - 0.2 12.1 0.0 31 5.0 0.0 2.5 2 0 0 2 2 2 0 RNA helicase CN_hydrolase PF00795.22 AAZ33524.1 - 1.1e-17 64.2 0.1 1.3e-17 64.0 0.1 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase URO-D PF01208.17 AAZ33525.1 - 7.7e-141 469.2 0.0 8.7e-141 469.1 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) COX_ARM PF06481.14 AAZ33526.1 - 2.6e-18 65.6 0.0 4.3e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 COX Aromatic Rich Motif COX2 PF00116.20 AAZ33526.1 - 1.2e-07 31.7 0.4 1.5e-05 24.8 0.0 2.3 1 1 1 2 2 2 2 Cytochrome C oxidase subunit II, periplasmic domain DUF4079 PF13301.6 AAZ33526.1 - 0.0012 19.0 0.2 0.0017 18.5 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4079) COX2_TM PF02790.15 AAZ33526.1 - 0.0037 17.4 2.4 0.0095 16.1 2.4 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, transmembrane domain K1 PF02960.14 AAZ33526.1 - 0.18 11.9 0.0 0.37 10.9 0.0 1.5 1 0 0 1 1 1 0 K1 glycoprotein Proton_antipo_N PF00662.20 AAZ33526.1 - 2 8.6 7.6 0.39 10.8 0.2 2.7 3 0 0 3 3 3 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Agglutinin PF07468.11 AAZ33527.1 - 0.021 15.1 0.0 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 Agglutinin domain DUF1654 PF07867.11 AAZ33528.1 - 3.4e-12 45.9 0.3 4.1e-12 45.7 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1654) GATase_6 PF13522.6 AAZ33529.1 - 1.6e-14 54.2 0.2 4e-14 52.9 0.2 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 AAZ33529.1 - 2.1e-11 43.8 0.0 8.6e-11 41.8 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 AAZ33529.1 - 3.2e-09 36.5 0.0 6.9e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 AAZ33529.1 - 1.2e-05 24.3 0.0 2.1e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferases class-II IU_nuc_hydro PF01156.19 AAZ33529.1 - 0.0048 16.5 0.0 0.0083 15.7 0.0 1.4 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase PRTase_2 PF15609.6 AAZ33529.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl transferase 2CSK_N PF08521.10 AAZ33531.1 - 2.2e-39 134.7 2.1 2.8e-39 134.4 0.2 2.1 2 0 0 2 2 2 1 Two-component sensor kinase N-terminal HATPase_c PF02518.26 AAZ33531.1 - 2.2e-18 66.8 0.0 4e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAZ33531.1 - 4.8e-14 52.1 1.1 1.9e-13 50.2 1.1 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AAZ33531.1 - 4.9e-06 26.8 0.7 4.9e-06 26.8 0.7 3.3 4 0 0 4 4 4 2 HAMP domain DUF1104 PF06518.11 AAZ33532.1 - 0.016 15.6 1.5 0.025 14.9 1.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1104) DUF5582 PF17819.1 AAZ33532.1 - 1.3 9.4 4.7 0.78 10.2 2.1 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5582) Fumerase PF05681.14 AAZ33533.1 - 7.5e-101 337.1 0.1 1e-100 336.6 0.1 1.2 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Fumerase_C PF05683.12 AAZ33533.1 - 2.9e-81 271.7 0.0 4.4e-81 271.1 0.0 1.3 1 0 0 1 1 1 1 Fumarase C-terminus PRTase_2 PF15609.6 AAZ33534.1 - 3.6e-58 196.2 0.0 6.5e-58 195.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase TRSP PF12500.8 AAZ33534.1 - 1.5e-20 73.4 0.0 5.2e-20 71.7 0.0 1.8 2 0 0 2 2 2 1 TRSP domain C terminus to PRTase_2 Pribosyltran PF00156.27 AAZ33534.1 - 0.00023 20.7 0.0 0.00041 19.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain EamA PF00892.20 AAZ33535.1 - 5.7e-21 75.1 34.4 4e-14 52.9 13.5 2.0 2 0 0 2 2 2 2 EamA-like transporter family TGT PF01702.18 AAZ33536.1 - 2.5e-148 493.9 0.0 3.4e-148 493.5 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Alginate_lyase2 PF08787.11 AAZ33537.1 - 7.3e-57 192.9 0.1 8.2e-57 192.8 0.1 1.0 1 0 0 1 1 1 1 Alginate lyase DUF5484 PF17583.2 AAZ33537.1 - 0.032 13.9 0.3 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5484) malic PF00390.19 AAZ33538.1 - 1.7e-28 99.6 0.2 1.1e-25 90.5 0.2 2.3 1 1 0 1 1 1 1 Malic enzyme, N-terminal domain Malic_M PF03949.15 AAZ33538.1 - 1e-24 87.3 1.0 3.5e-24 85.5 1.0 1.8 1 1 0 1 1 1 1 Malic enzyme, NAD binding domain AlaDh_PNT_C PF01262.21 AAZ33538.1 - 0.0034 16.7 0.8 0.0069 15.7 0.8 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.21 AAZ33538.1 - 0.033 13.9 0.0 0.063 13.0 0.0 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Shikimate_DH PF01488.20 AAZ33538.1 - 0.072 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Asp_Glu_race PF01177.22 AAZ33539.1 - 1.1e-11 45.0 0.3 1.3e-11 44.8 0.3 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Amdase PF17645.1 AAZ33539.1 - 0.0029 17.3 1.3 0.0034 17.0 0.4 1.7 2 1 1 3 3 3 1 Arylmalonate decarboxylase AdoHcyase PF05221.17 AAZ33540.1 - 6.3e-127 422.8 0.0 6.9e-73 245.4 0.4 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 AAZ33540.1 - 3.3e-58 196.3 1.3 1.9e-57 193.9 1.3 2.1 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_7 PF13241.6 AAZ33540.1 - 4.3e-05 23.9 0.0 0.00011 22.5 0.0 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding IlvN PF07991.12 AAZ33540.1 - 0.0022 17.6 0.0 0.006 16.2 0.0 1.7 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 AAZ33540.1 - 0.0054 17.0 0.1 0.012 15.9 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain 2-Hacid_dh_C PF02826.19 AAZ33540.1 - 0.0071 15.7 0.1 0.13 11.6 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 AAZ33540.1 - 0.12 12.1 0.1 0.26 11.0 0.1 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase CTNNB1_binding PF08347.11 AAZ33541.1 - 6.3 6.9 13.8 7.1 6.8 13.8 1.1 1 0 0 1 1 1 0 N-terminal CTNNB1 binding Peptidase_M78 PF06114.13 AAZ33542.1 - 9.9e-22 77.2 0.0 1.6e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 IrrE N-terminal-like domain HTH_3 PF01381.22 AAZ33542.1 - 1.3e-06 28.3 0.0 5.4e-06 26.4 0.0 2.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 AAZ33542.1 - 3.3e-06 27.4 3.6 1.6e-05 25.2 0.5 2.8 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_25 PF13413.6 AAZ33542.1 - 0.01 15.7 0.1 0.063 13.1 0.0 2.4 2 1 1 3 3 3 1 Helix-turn-helix domain HTH_19 PF12844.7 AAZ33542.1 - 0.014 15.4 0.0 0.084 12.9 0.0 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain Peptidase_M91 PF14891.6 AAZ33542.1 - 0.081 13.2 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 Effector protein CoA_transf_3 PF02515.17 AAZ33543.1 - 8.7e-56 189.6 0.1 1.1e-55 189.3 0.1 1.0 1 0 0 1 1 1 1 CoA-transferase family III SAM_4 PF18017.1 AAZ33543.1 - 0.12 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) LysR_substrate PF03466.20 AAZ33544.1 - 1e-31 110.0 3.4 1.6e-31 109.3 3.4 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ33544.1 - 2.5e-19 69.0 0.3 4.8e-19 68.1 0.3 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family Acyl-ACP_TE PF01643.17 AAZ33545.1 - 1.8e-10 40.5 0.0 6.1e-05 22.4 0.0 2.0 1 1 1 2 2 2 2 Acyl-ACP thioesterase 4HBT_2 PF13279.6 AAZ33545.1 - 7.1e-10 39.4 0.0 8.6e-10 39.2 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 AAZ33545.1 - 3.8e-08 33.6 0.0 5.9e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily NmrA PF05368.13 AAZ33546.1 - 2.1e-20 73.3 0.0 2.6e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 AAZ33546.1 - 2.8e-08 33.9 0.1 5e-08 33.1 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 AAZ33546.1 - 0.00017 21.8 0.1 0.00052 20.3 0.0 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 AAZ33546.1 - 0.00071 19.6 0.5 0.011 15.8 0.5 2.4 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 AAZ33546.1 - 0.099 12.1 0.2 0.18 11.3 0.2 1.4 1 0 0 1 1 1 0 short chain dehydrogenase DAO PF01266.24 AAZ33546.1 - 0.28 10.7 3.1 3.1 7.3 2.2 2.7 1 1 1 2 2 2 0 FAD dependent oxidoreductase Glyco_hydro_15 PF00723.21 AAZ33547.1 - 1.3e-49 169.2 0.1 2.9e-47 161.5 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 15 TPR_4 PF07721.14 AAZ33547.1 - 0.047 14.3 1.8 68 4.5 0.1 4.3 3 1 0 3 3 3 0 Tetratricopeptide repeat BPD_transp_1 PF00528.22 AAZ33548.1 - 2.7e-10 40.3 13.6 2.7e-10 40.3 13.6 2.2 1 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component TonB_dep_Rec PF00593.24 AAZ33549.1 - 1.1e-34 121.1 48.8 1.1e-34 121.1 47.4 1.6 1 1 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AAZ33549.1 - 1.8e-20 73.5 0.7 5.5e-20 71.9 0.7 1.9 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain BPD_transp_2 PF02653.16 AAZ33550.1 - 2.1e-30 105.8 30.7 2.7e-30 105.4 30.7 1.1 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component DUF883 PF05957.13 AAZ33550.1 - 0.19 12.3 4.2 0.53 10.9 4.2 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Peripla_BP_1 PF00532.21 AAZ33551.1 - 9.5e-18 64.6 0.0 1.1e-17 64.3 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 AAZ33551.1 - 7e-17 60.9 0.5 2e-16 59.5 0.2 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 AAZ33551.1 - 8.7e-11 41.9 0.0 1.2e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_3 PF13377.6 AAZ33551.1 - 0.0002 21.8 0.7 0.001 19.4 0.6 2.0 2 0 0 2 2 2 1 Periplasmic binding protein-like domain HTH_3 PF01381.22 AAZ33551.1 - 0.051 13.6 0.1 0.19 11.8 0.1 2.0 3 0 0 3 3 3 0 Helix-turn-helix IucA_IucC PF04183.12 AAZ33552.1 - 3.2e-42 144.7 0.0 5.7e-42 143.9 0.0 1.4 1 0 0 1 1 1 1 IucA / IucC family FhuF PF06276.12 AAZ33552.1 - 1.1e-33 117.0 2.8 1.1e-33 117.0 2.8 1.8 2 0 0 2 2 2 1 Ferric iron reductase FhuF-like transporter Peptidase_S49_N PF08496.10 AAZ33553.1 - 1.5e-53 180.9 2.2 2.6e-53 180.2 2.2 1.4 1 0 0 1 1 1 1 Peptidase family S49 N-terminal Peptidase_S49 PF01343.18 AAZ33553.1 - 4.9e-45 153.2 0.0 7.4e-45 152.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S49 SDH_sah PF01972.16 AAZ33553.1 - 0.014 14.4 0.1 0.021 13.8 0.1 1.3 1 0 0 1 1 1 0 Serine dehydrogenase proteinase Exostosin PF03016.15 AAZ33553.1 - 0.055 12.7 0.2 2.4 7.3 0.1 2.1 2 0 0 2 2 2 0 Exostosin family DUF4337 PF14235.6 AAZ33553.1 - 0.067 13.3 1.0 0.086 12.9 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) OprD PF03573.13 AAZ33554.1 - 1.6e-137 458.7 9.6 1.8e-137 458.6 9.6 1.0 1 0 0 1 1 1 1 outer membrane porin, OprD family DUF347 PF03988.12 AAZ33555.1 - 4.2e-67 222.2 40.3 1.5e-18 66.7 5.9 4.0 4 0 0 4 4 4 4 Repeat of Unknown Function (DUF347) DUF3149 PF11346.8 AAZ33555.1 - 0.04 13.5 0.0 0.04 13.5 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3149) DUF4293 PF14126.6 AAZ33555.1 - 0.058 13.6 4.9 1.9 8.8 3.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) DUF4389 PF14333.6 AAZ33556.1 - 1.4e-28 98.6 0.4 1.7e-28 98.3 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4389) TusA PF01206.17 AAZ33557.1 - 2.8e-20 71.9 0.0 3.2e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 Sulfurtransferase TusA Hexapep PF00132.24 AAZ33558.1 - 2.6e-17 61.8 16.7 1.2e-05 24.8 0.6 4.9 4 1 1 5 5 5 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AAZ33558.1 - 4.5e-06 26.3 10.3 0.0041 16.8 0.7 4.0 3 1 1 4 4 4 3 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 AAZ33558.1 - 0.069 11.3 3.0 0.092 10.9 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Fucokinase PF07959.12 AAZ33558.1 - 0.079 11.9 0.1 0.14 11.1 0.1 1.5 1 1 0 1 1 1 0 L-fucokinase TonB_dep_Rec PF00593.24 AAZ33559.1 - 6.1e-54 184.7 29.7 1.9e-53 183.0 17.1 2.1 1 1 1 2 2 2 2 TonB dependent receptor Plug PF07715.15 AAZ33559.1 - 6e-12 46.1 0.1 1.5e-11 44.8 0.1 1.7 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain BPD_transp_1 PF00528.22 AAZ33560.1 - 3.4e-16 59.5 8.7 3.4e-16 59.5 8.7 1.3 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component Stevor PF17410.2 AAZ33560.1 - 0.033 13.7 0.7 0.04 13.5 0.7 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF2892 PF11127.8 AAZ33561.1 - 4.5e-07 29.8 0.1 6.8e-07 29.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2892) PCRF PF03462.18 AAZ33562.1 - 3.4e-54 183.7 0.7 9.2e-54 182.3 0.1 1.9 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 AAZ33562.1 - 2.7e-41 140.1 0.8 5.4e-41 139.2 0.8 1.5 1 0 0 1 1 1 1 RF-1 domain MIR PF02815.19 AAZ33562.1 - 0.016 15.1 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 MIR domain DnaB_bind PF10410.9 AAZ33562.1 - 0.18 12.0 1.7 1.1 9.5 0.4 2.6 2 0 0 2 2 2 0 DnaB-helicase binding domain of primase ABC_tran_CTD PF16326.5 AAZ33562.1 - 2.6 8.4 8.7 6 7.2 0.0 3.3 3 0 0 3 3 3 0 ABC transporter C-terminal domain RNase_T PF00929.24 AAZ33563.1 - 1e-36 127.0 0.0 1.2e-36 126.7 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 AAZ33563.1 - 0.13 11.9 0.1 1.1 8.9 0.0 2.0 2 0 0 2 2 2 0 3'-5' exonuclease TonB_dep_Rec PF00593.24 AAZ33564.1 - 1.5e-53 183.3 26.0 1.5e-53 183.3 26.0 2.1 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 AAZ33564.1 - 4.4e-15 56.2 0.9 9.8e-15 55.0 0.9 1.6 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain DUF2490 PF10677.9 AAZ33564.1 - 0.12 12.3 2.9 0.92 9.4 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2490) Acetyltransf_7 PF13508.7 AAZ33565.1 - 1.2e-07 32.0 0.0 1.8e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAZ33565.1 - 2.3e-06 27.8 0.0 2.7e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AAZ33565.1 - 9.4e-06 25.6 0.0 1.2e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AAZ33565.1 - 0.19 11.8 0.0 0.4 10.8 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF805 PF05656.14 AAZ33566.1 - 5.9e-21 74.8 1.6 5.9e-21 74.8 1.6 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF805) Peptidase_U4 PF03419.13 AAZ33566.1 - 0.00013 21.4 0.0 0.00016 21.1 0.0 1.1 1 0 0 1 1 1 1 Sporulation factor SpoIIGA Ribosomal_L12 PF00542.19 AAZ33566.1 - 0.067 13.6 0.0 0.15 12.4 0.0 1.7 1 1 0 1 1 1 0 Ribosomal protein L7/L12 C-terminal domain UPF0126 PF03458.13 AAZ33566.1 - 2.2 8.2 10.2 0.33 10.8 0.8 2.7 3 0 0 3 3 3 0 UPF0126 domain ABC2_membrane_3 PF12698.7 AAZ33566.1 - 3.5 6.6 7.0 21 4.1 5.8 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein Sigma54_activat PF00158.26 AAZ33567.1 - 8.8e-55 185.0 0.0 1.4e-54 184.3 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain HTH_50 PF18024.1 AAZ33567.1 - 1.8e-18 65.9 0.0 5e-18 64.5 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma54_activ_2 PF14532.6 AAZ33567.1 - 2.7e-15 56.7 0.0 5.3e-15 55.7 0.0 1.5 1 1 0 1 1 1 1 Sigma-54 interaction domain PAS_8 PF13188.7 AAZ33567.1 - 3.5e-05 23.7 0.1 0.0002 21.3 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 AAZ33567.1 - 5.8e-05 23.1 0.0 0.00021 21.2 0.0 1.9 1 0 0 1 1 1 1 PAS fold ACT PF01842.25 AAZ33567.1 - 9.8e-05 22.0 0.0 0.00025 20.7 0.0 1.7 1 0 0 1 1 1 1 ACT domain HTH_38 PF13936.6 AAZ33567.1 - 0.001 18.7 0.0 0.0023 17.6 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain PAS_4 PF08448.10 AAZ33567.1 - 0.038 14.2 0.0 0.16 12.2 0.0 2.1 1 1 0 1 1 1 0 PAS fold PAS_9 PF13426.7 AAZ33567.1 - 0.085 13.1 0.0 0.37 11.1 0.0 2.1 2 0 0 2 2 2 0 PAS domain AAA_5 PF07728.14 AAZ33567.1 - 0.088 12.8 0.0 0.26 11.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) GST_C_2 PF13410.6 AAZ33568.1 - 1.9e-12 47.0 0.1 4.1e-12 45.9 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 AAZ33568.1 - 1.2e-09 38.3 0.0 2e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 AAZ33568.1 - 7.7e-07 29.4 0.0 1.7e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 AAZ33568.1 - 1.3e-06 28.5 0.0 2.2e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 AAZ33568.1 - 3.2e-05 23.6 0.0 5.6e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 AAZ33568.1 - 9.2e-05 22.7 0.0 0.00022 21.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 AAZ33568.1 - 0.0012 19.2 0.0 0.0023 18.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain MCPsignal PF00015.21 AAZ33569.1 - 2e-34 118.9 34.3 4.5e-34 117.7 16.9 2.9 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain 4HB_MCP_1 PF12729.7 AAZ33569.1 - 2.5e-17 63.0 0.3 2.5e-17 63.0 0.3 3.4 3 1 0 3 3 3 1 Four helix bundle sensory module for signal transduction HAMP PF00672.25 AAZ33569.1 - 1.8e-08 34.7 0.9 1.8e-08 34.7 0.9 3.2 4 1 0 4 4 4 1 HAMP domain Vma12 PF11712.8 AAZ33569.1 - 0.1 12.6 0.0 0.1 12.6 0.0 3.3 4 1 0 4 4 4 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Peptidase_S64 PF08192.11 AAZ33569.1 - 0.13 10.7 8.2 0.12 10.8 6.5 1.7 1 1 1 2 2 2 0 Peptidase family S64 Syntaxin-6_N PF09177.11 AAZ33569.1 - 0.19 12.3 3.6 0.59 10.7 0.3 2.8 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Fib_alpha PF08702.10 AAZ33569.1 - 0.47 10.6 9.6 0.14 12.4 1.1 3.4 3 2 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 AAZ33569.1 - 0.5 10.4 13.9 2.6 8.1 1.1 3.9 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) BRE1 PF08647.11 AAZ33569.1 - 6 7.0 8.9 0.43 10.7 1.0 3.2 3 1 1 4 4 4 0 BRE1 E3 ubiquitin ligase HTH_24 PF13412.6 AAZ33570.1 - 1.1e-18 66.6 0.3 1.6e-18 66.0 0.3 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 AAZ33570.1 - 3.5e-17 62.0 1.4 5.8e-17 61.2 1.4 1.4 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain AsnC_trans_reg PF01037.21 AAZ33570.1 - 2.2e-14 53.2 0.0 4e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_20 PF12840.7 AAZ33570.1 - 0.00026 21.0 0.1 0.0005 20.1 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 AAZ33570.1 - 0.0064 16.3 0.2 0.013 15.4 0.2 1.5 1 0 0 1 1 1 1 MarR family MarR PF01047.22 AAZ33570.1 - 0.026 14.4 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 MarR family Rrf2 PF02082.20 AAZ33570.1 - 0.054 13.9 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator Metallophos PF00149.28 AAZ33571.1 - 1.7e-19 71.2 0.0 2.6e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AAZ33571.1 - 4e-13 49.9 0.0 1.5e-12 48.0 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain LamB_YcsF PF03746.16 AAZ33571.1 - 0.067 12.9 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 LamB/YcsF family Flavin_Reduct PF01613.18 AAZ33572.1 - 1.5e-17 64.1 0.0 1.9e-17 63.7 0.0 1.0 1 0 0 1 1 1 1 Flavin reductase like domain Sel1 PF08238.12 AAZ33573.1 - 1.1e-12 48.1 8.1 3.6e-08 33.8 0.6 2.7 3 0 0 3 3 3 2 Sel1 repeat TPR_6 PF13174.6 AAZ33573.1 - 1.4 9.7 6.7 1.3 9.8 0.2 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 AAZ33573.1 - 5.2 7.1 6.3 63 3.6 0.3 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat AMP-binding PF00501.28 AAZ33574.1 - 6.8e-286 947.4 0.0 3.2e-100 335.7 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 AAZ33574.1 - 1.4e-142 475.6 0.0 1.4e-105 353.6 0.0 2.1 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.25 AAZ33574.1 - 6.3e-38 129.0 2.0 6.3e-12 45.7 0.1 4.3 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.6 AAZ33574.1 - 1.5e-33 115.6 0.0 1.5e-10 41.9 0.0 3.8 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain Nitroreductase PF00881.24 AAZ33574.1 - 1e-15 58.2 0.0 3.9e-15 56.3 0.0 2.1 1 0 0 1 1 1 1 Nitroreductase family FeoA PF04023.14 AAZ33574.1 - 0.059 13.6 1.5 23 5.4 0.1 4.3 5 0 0 5 5 5 0 FeoA domain Flg_hook PF02120.16 AAZ33574.1 - 0.13 12.2 2.4 2.7 7.9 0.1 3.2 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK Hpt PF01627.23 AAZ33575.1 - 3.1e-14 53.0 1.1 4.6e-14 52.4 1.1 1.3 1 0 0 1 1 1 1 Hpt domain UvrD_C_2 PF13538.6 AAZ33575.1 - 0.12 12.2 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DciA PF05258.12 AAZ33576.1 - 2.2e-12 47.2 1.6 2.6e-12 47.0 0.7 1.5 2 0 0 2 2 2 1 Dna[CI] antecedent, DciA BPD_transp_2 PF02653.16 AAZ33577.1 - 2.4e-38 131.8 43.8 3.2e-38 131.4 43.8 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component OmpH PF03938.14 AAZ33578.1 - 2.5e-19 70.0 7.7 3e-19 69.7 7.7 1.1 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) V-ATPase_G_2 PF16999.5 AAZ33578.1 - 0.02 15.3 1.0 0.033 14.6 1.0 1.4 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit DUF484 PF04340.12 AAZ33579.1 - 1.2e-70 237.8 0.6 1.3e-70 237.6 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF484 GATase PF00117.28 AAZ33580.1 - 2.9e-08 33.7 0.0 3.6e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AAZ33580.1 - 0.004 16.9 0.0 0.0062 16.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase C26 dUTPase PF00692.19 AAZ33581.1 - 6.4e-06 25.9 0.0 2.4e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 dUTPase Rick_17kDa_Anti PF05433.15 AAZ33582.1 - 2.6e-10 40.0 20.5 2.6e-10 40.0 20.5 2.7 2 1 0 2 2 2 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 AAZ33582.1 - 9.9e-06 25.5 24.6 3.1e-05 23.9 13.3 2.6 2 0 0 2 2 2 2 Glycine zipper Gly-zipper_YMGG PF13441.6 AAZ33582.1 - 0.00075 19.2 26.9 0.0019 17.9 17.6 2.3 2 0 0 2 2 2 2 YMGG-like Gly-zipper DUF533 PF04391.12 AAZ33582.1 - 0.61 9.6 2.7 0.31 10.6 0.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF533) Bacteriocin_IIc PF10439.9 AAZ33582.1 - 2.9 8.1 21.5 0.42 10.8 10.2 2.4 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Transgly_assoc PF04226.13 AAZ33582.1 - 9 6.6 16.3 4.7 7.5 8.1 2.5 2 1 0 2 2 2 0 Transglycosylase associated protein YicC_N PF03755.13 AAZ33583.1 - 4.3e-38 131.1 0.2 1.4e-37 129.5 0.0 1.9 2 1 0 2 2 2 1 YicC-like family, N-terminal region DUF1732 PF08340.11 AAZ33583.1 - 1e-34 118.4 2.3 1.4e-34 117.9 1.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1732) SpoIIM PF01944.17 AAZ33584.1 - 1.7e-33 115.9 14.8 1.7e-33 115.9 14.8 1.7 2 0 0 2 2 2 1 Stage II sporulation protein M Acyltransferase PF01553.21 AAZ33585.1 - 2.8e-21 75.5 0.0 5.2e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase TsaE PF02367.17 AAZ33586.1 - 4.4e-39 133.3 0.0 4.9e-39 133.2 0.0 1.0 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 AAZ33586.1 - 0.048 13.4 0.1 3 7.6 0.1 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_33 PF13671.6 AAZ33586.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.5 2 0 0 2 2 2 0 AAA domain DUF58 PF01882.18 AAZ33586.1 - 0.19 12.0 0.0 0.29 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF58 Phage_integrase PF00589.22 AAZ33587.1 - 4.7e-12 46.0 0.0 8.5e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family Sigma54_activat PF00158.26 AAZ33588.1 - 1e-68 230.3 0.1 2.1e-68 229.3 0.0 1.5 2 0 0 2 2 2 1 Sigma-54 interaction domain XylR_N PF06505.11 AAZ33588.1 - 3.6e-36 122.9 0.3 1.1e-35 121.4 0.1 1.9 2 0 0 2 2 2 1 Activator of aromatic catabolism Sigma54_activ_2 PF14532.6 AAZ33588.1 - 7.9e-20 71.4 0.0 3.2e-19 69.4 0.0 2.0 2 1 0 2 2 2 1 Sigma-54 interaction domain V4R PF02830.18 AAZ33588.1 - 1.8e-17 63.1 2.4 4.1e-17 61.9 2.4 1.6 1 0 0 1 1 1 1 V4R domain HTH_8 PF02954.19 AAZ33588.1 - 1e-10 41.2 0.3 2.5e-10 40.0 0.1 1.8 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 AAZ33588.1 - 1.1e-07 31.9 0.0 2.3e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 AAZ33588.1 - 2.8e-05 23.6 0.1 0.046 13.1 0.0 2.2 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA PF00004.29 AAZ33588.1 - 0.0003 21.2 0.0 0.00057 20.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AAZ33588.1 - 0.0039 17.6 0.6 0.011 16.1 0.1 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_3 PF07726.11 AAZ33588.1 - 0.036 13.9 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 AAZ33588.1 - 0.061 13.4 0.0 0.21 11.7 0.0 1.9 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_32 PF13654.6 AAZ33588.1 - 0.11 11.3 0.1 0.58 8.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 AAZ33588.1 - 0.13 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Hexapep PF00132.24 AAZ33589.1 - 1.6e-11 43.4 6.0 8.2e-07 28.5 0.6 2.8 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) SATase_N PF06426.14 AAZ33589.1 - 0.00078 19.8 0.0 0.0013 19.0 0.0 1.4 1 0 0 1 1 1 1 Serine acetyltransferase, N-terminal Hexapep_2 PF14602.6 AAZ33589.1 - 0.027 14.2 9.9 0.073 12.8 2.4 3.0 2 2 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase HlyD_D23 PF16576.5 AAZ33591.1 - 2.8e-14 52.9 9.4 7.7e-14 51.4 9.4 1.7 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AAZ33591.1 - 3.2e-14 53.5 6.4 2.5e-11 44.2 1.1 3.2 3 0 0 3 3 3 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AAZ33591.1 - 3e-12 46.2 10.2 2.4e-07 30.5 5.5 3.3 2 1 0 2 2 2 2 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AAZ33591.1 - 0.00014 21.6 3.1 0.12 12.3 0.1 3.1 3 1 0 3 3 3 2 Biotin-requiring enzyme PTS_EIIA_1 PF00358.20 AAZ33591.1 - 0.0064 16.2 0.2 4.5 7.1 0.0 2.6 3 0 0 3 3 3 2 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 DUF4685 PF15737.5 AAZ33591.1 - 0.025 15.0 0.2 0.055 13.9 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4685) TrbI_Ftype PF09677.10 AAZ33591.1 - 0.093 13.1 2.4 0.24 11.7 2.4 1.7 1 0 0 1 1 1 0 Type-F conjugative transfer system protein (TrbI_Ftype) ADH_N_2 PF16884.5 AAZ33592.1 - 3.1e-39 133.2 0.0 8.4e-39 131.8 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 AAZ33592.1 - 4e-23 81.8 1.0 6.8e-23 81.1 0.6 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AAZ33592.1 - 1.3e-12 48.9 0.1 2.8e-12 47.8 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF2855 PF11017.8 AAZ33592.1 - 0.24 11.1 0.0 1 9.0 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2855) FliE PF02049.18 AAZ33593.1 - 2.6e-31 107.6 6.3 3.3e-31 107.2 6.3 1.2 1 0 0 1 1 1 1 Flagellar hook-basal body complex protein FliE Ald_Xan_dh_C2 PF02738.18 AAZ33593.1 - 0.016 13.7 0.9 0.017 13.6 0.9 1.0 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase DUF86 PF01934.17 AAZ33593.1 - 0.025 14.4 0.0 0.033 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF86 FtsK_gamma PF09397.10 AAZ33593.1 - 0.39 10.6 2.7 5.8 6.8 0.1 2.8 2 1 1 3 3 3 0 Ftsk gamma domain AMP-binding PF00501.28 AAZ33594.1 - 6.5e-80 268.8 0.0 8.5e-80 268.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAZ33594.1 - 8.8e-07 29.8 0.0 2.3e-06 28.5 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Glycos_transf_2 PF00535.26 AAZ33595.1 - 3.1e-10 40.1 0.0 5e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAZ33595.1 - 4.5e-06 26.7 0.0 5.9e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 AAA_21 PF13304.6 AAZ33596.1 - 1.6e-19 70.9 0.1 2.1e-14 54.0 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AAZ33596.1 - 1.2e-18 67.9 0.0 6.5e-08 32.7 0.0 2.5 3 0 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 AAZ33596.1 - 1.4e-15 58.3 0.0 2.3e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 AAZ33596.1 - 6.8e-10 38.7 0.0 0.00058 19.4 0.0 2.3 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAZ33596.1 - 3.7e-05 23.4 0.0 8.8e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain MukB PF04310.12 AAZ33596.1 - 0.006 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 MukB N-terminal AAA_27 PF13514.6 AAZ33596.1 - 0.015 14.9 0.0 0.033 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2813 PF11398.8 AAZ33596.1 - 0.022 14.1 0.0 0.22 10.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) Rieske PF00355.26 AAZ33597.1 - 1.6e-12 47.2 0.0 1.8e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 AAZ33597.1 - 0.21 11.5 0.0 0.47 10.4 0.0 1.5 1 1 0 1 1 1 0 Rieske-like [2Fe-2S] domain Peptidase_M18 PF02127.15 AAZ33598.1 - 2e-143 478.3 0.0 2.3e-143 478.1 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 AAZ33598.1 - 4.7e-09 35.7 0.2 5.8e-05 22.3 0.1 2.5 3 0 0 3 3 3 2 M42 glutamyl aminopeptidase DUF3108 PF11306.8 AAZ33599.1 - 1.6e-24 87.2 0.3 1.9e-24 86.9 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3108) DUF3600 PF12207.8 AAZ33599.1 - 0.13 12.2 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3600) Cupin_2 PF07883.11 AAZ33600.1 - 1.2e-11 44.2 0.2 2.1e-11 43.4 0.2 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 AAZ33600.1 - 1.6e-07 31.0 0.0 2.3e-07 30.6 0.0 1.2 1 1 0 1 1 1 1 Cupin Auxin_BP PF02041.16 AAZ33600.1 - 0.0073 16.0 0.1 0.011 15.3 0.1 1.3 1 1 0 1 1 1 1 Auxin binding protein Cupin_4 PF08007.12 AAZ33600.1 - 0.048 13.1 0.0 0.064 12.7 0.0 1.4 1 1 0 1 1 1 0 Cupin superfamily protein Cupin_7 PF12973.7 AAZ33600.1 - 0.076 12.9 0.4 0.2 11.6 0.4 1.7 1 1 0 1 1 1 0 ChrR Cupin-like domain Response_reg PF00072.24 AAZ33601.1 - 2e-23 82.7 0.0 2.8e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAZ33601.1 - 4e-23 81.3 0.0 6.5e-23 80.6 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal DUF58 PF01882.18 AAZ33602.1 - 5.7e-11 42.6 0.0 1.1e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF58 CcmD PF04995.14 AAZ33602.1 - 4 7.6 6.1 1.1 9.4 0.7 2.7 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) CT_A_B PF02626.15 AAZ33603.1 - 4.4e-90 301.9 0.0 7.9e-90 301.1 0.0 1.4 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 AAZ33603.1 - 2.6e-63 213.3 0.0 4.5e-63 212.6 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CT_C_D PF02682.16 AAZ33603.1 - 3.5e-46 157.5 0.0 6.9e-46 156.5 0.0 1.5 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D Biotin_carb_N PF00289.22 AAZ33603.1 - 5.3e-41 139.6 0.5 2.3e-40 137.6 0.1 2.3 3 0 0 3 3 3 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 AAZ33603.1 - 5e-33 113.4 0.0 3e-32 110.9 0.0 2.3 3 0 0 3 3 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 AAZ33603.1 - 5.5e-16 58.2 0.2 1.9e-15 56.4 0.4 1.8 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 AAZ33603.1 - 7.4e-12 45.2 0.0 1.5e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 AAZ33603.1 - 1e-06 28.4 0.0 1.9e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 AAZ33603.1 - 1.6e-06 27.8 4.5 0.0021 17.8 0.1 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.14 AAZ33603.1 - 0.00011 22.2 0.0 0.0002 21.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 AAZ33603.1 - 0.00014 22.5 3.8 0.013 16.1 0.8 2.6 2 0 0 2 2 2 1 HlyD family secretion protein RimK PF08443.11 AAZ33603.1 - 0.00019 21.1 0.0 0.00037 20.2 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.6 AAZ33603.1 - 0.001 18.6 0.0 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD_D23 PF16576.5 AAZ33603.1 - 0.0081 15.4 0.8 0.25 10.6 0.1 2.2 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATPgrasp_Ter PF15632.6 AAZ33603.1 - 0.024 14.4 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon GCV_H PF01597.19 AAZ33603.1 - 0.034 14.0 0.1 0.081 12.8 0.1 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein NQRA PF05896.11 AAZ33603.1 - 0.11 12.0 0.1 0.18 11.2 0.1 1.2 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) RnfC_N PF13375.6 AAZ33603.1 - 0.12 12.3 0.5 0.24 11.4 0.5 1.4 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Acetyltransf_1 PF00583.25 AAZ33605.1 - 2.4e-15 56.8 0.0 3e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAZ33605.1 - 8.6e-10 38.9 0.0 1.2e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAZ33605.1 - 1.6e-09 37.7 0.0 2.1e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AAZ33605.1 - 2.6e-05 24.3 0.0 3.3e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAZ33605.1 - 0.00028 20.8 0.0 0.00042 20.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 AAZ33605.1 - 0.00059 19.9 0.0 0.001 19.1 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.6 AAZ33605.1 - 0.0028 17.3 0.0 0.008 15.9 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 AAZ33605.1 - 0.11 12.6 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyoxalase PF00903.25 AAZ33606.1 - 7.1e-23 81.2 0.0 8.5e-23 81.0 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 AAZ33606.1 - 2.7e-10 40.5 0.0 1.1e-06 28.9 0.0 2.3 1 1 1 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 AAZ33606.1 - 0.00016 22.4 0.0 0.00027 21.7 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 AAZ33606.1 - 0.0027 17.8 0.0 0.014 15.5 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 AAZ33606.1 - 0.088 12.8 0.1 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 Glyoxalase-like domain HD_4 PF13328.6 AAZ33607.1 - 8.5e-46 155.5 2.1 1.5e-45 154.7 2.1 1.4 1 0 0 1 1 1 1 HD domain RelA_SpoT PF04607.17 AAZ33607.1 - 3.4e-38 130.5 0.0 7.6e-38 129.4 0.0 1.5 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins TGS PF02824.21 AAZ33607.1 - 1.8e-22 79.2 0.0 5.7e-22 77.5 0.0 2.0 1 0 0 1 1 1 1 TGS domain ACT_4 PF13291.6 AAZ33607.1 - 9.1e-18 64.6 0.3 2.3e-17 63.3 0.3 1.7 1 0 0 1 1 1 1 ACT domain ACT PF01842.25 AAZ33607.1 - 1.1e-05 25.0 0.1 2.7e-05 23.8 0.1 1.7 1 0 0 1 1 1 1 ACT domain GspH PF12019.8 AAZ33608.1 - 5.3e-11 42.9 0.2 7e-11 42.5 0.2 1.1 1 0 0 1 1 1 1 Type II transport protein GspH N_methyl PF07963.12 AAZ33608.1 - 3.2e-07 29.6 2.1 6.8e-07 28.6 2.1 1.6 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif PSI_PSAK PF01241.18 AAZ33608.1 - 0.11 12.6 0.8 0.37 10.8 0.4 1.9 2 0 0 2 2 2 0 Photosystem I psaG / psaK 2-Hacid_dh_C PF02826.19 AAZ33609.1 - 8.5e-47 158.8 0.0 1.2e-46 158.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 AAZ33609.1 - 0.00078 20.0 0.1 0.0015 19.0 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 AAZ33609.1 - 0.0011 19.2 0.0 0.0016 18.6 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh PF00389.30 AAZ33609.1 - 0.027 14.1 0.0 0.056 13.1 0.0 1.6 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IlvN PF07991.12 AAZ33609.1 - 0.031 13.9 0.0 0.044 13.4 0.0 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain SBP_bac_5 PF00496.22 AAZ33610.1 - 1.8e-62 211.5 0.1 2.9e-62 210.8 0.1 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle NUDIX PF00293.28 AAZ33611.1 - 3.7e-14 52.9 0.1 7.2e-14 52.0 0.0 1.4 2 0 0 2 2 2 1 NUDIX domain PHP PF02811.19 AAZ33612.1 - 1.1e-07 32.3 0.0 1.1e-07 32.3 0.0 1.2 1 1 0 1 1 1 1 PHP domain PHP_C PF13263.6 AAZ33612.1 - 0.12 12.1 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 PHP-associated LigD_N PF13298.6 AAZ33613.1 - 1.1e-40 138.1 0.1 3.3e-40 136.6 0.0 1.9 2 0 0 2 2 2 1 DNA polymerase Ligase (LigD) DNA_ligase_A_M PF01068.21 AAZ33613.1 - 1e-25 90.6 0.0 1.8e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.15 AAZ33613.1 - 7.6e-25 87.4 0.0 2.2e-24 85.9 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_primase_S PF01896.19 AAZ33613.1 - 2.3e-06 27.8 0.0 3.9e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 DNA primase small subunit HTH_18 PF12833.7 AAZ33614.1 - 1.8e-22 79.4 0.4 7.8e-22 77.3 0.0 2.2 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAZ33614.1 - 3.6e-16 58.8 0.0 4.5e-08 33.0 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family AraC_binding PF02311.19 AAZ33614.1 - 0.0031 17.4 0.2 0.0059 16.5 0.2 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain PLDc_N PF13396.6 AAZ33615.1 - 1.4e-11 44.1 7.7 1.4e-11 44.1 7.7 1.4 2 0 0 2 2 2 1 Phospholipase_D-nuclease N-terminal FeoB_associated PF12669.7 AAZ33615.1 - 0.61 10.5 0.2 0.61 10.5 0.2 2.1 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein LysR_substrate PF03466.20 AAZ33616.1 - 3e-26 92.1 1.0 6e-26 91.1 1.0 1.4 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ33616.1 - 1.1e-18 66.9 0.2 2.7e-18 65.7 0.2 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AAZ33616.1 - 1.2e-05 25.0 0.0 2.4e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain MarR_2 PF12802.7 AAZ33616.1 - 2.1e-05 24.3 0.5 0.00013 21.8 0.1 2.2 2 0 0 2 2 2 1 MarR family DUF1349 PF07081.11 AAZ33618.1 - 1.3e-65 220.5 0.0 1.4e-65 220.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) GH43_C2 PF17851.1 AAZ33618.1 - 0.007 16.1 0.0 0.0081 15.9 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain HrpF PF06266.12 AAZ33619.1 - 2.7e-15 56.4 0.7 3e-15 56.3 0.7 1.0 1 0 0 1 1 1 1 HrpF protein MCPsignal PF00015.21 AAZ33620.1 - 2.3e-46 157.8 40.7 1.4e-45 155.2 23.0 3.4 1 1 2 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain 4HB_MCP_1 PF12729.7 AAZ33620.1 - 1.8e-17 63.5 0.6 1.8e-17 63.5 0.6 3.5 3 2 1 4 4 4 1 Four helix bundle sensory module for signal transduction HAMP PF00672.25 AAZ33620.1 - 1.8e-09 37.8 12.2 1.8e-08 34.6 0.6 4.5 5 0 0 5 5 4 1 HAMP domain KASH_CCD PF14662.6 AAZ33620.1 - 0.027 14.3 1.0 0.027 14.3 1.0 2.8 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Laminin_II PF06009.12 AAZ33620.1 - 0.07 13.1 27.3 0.065 13.2 7.8 4.5 2 2 2 4 4 4 0 Laminin Domain II Tropomyosin_1 PF12718.7 AAZ33620.1 - 0.087 13.0 7.2 1.2 9.2 0.8 2.9 2 0 0 2 2 2 0 Tropomyosin like COG2 PF06148.11 AAZ33620.1 - 0.087 12.9 8.5 0.34 11.0 1.0 3.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF948 PF06103.11 AAZ33620.1 - 0.15 12.3 28.7 0.17 12.2 1.3 4.8 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) BLOC1_2 PF10046.9 AAZ33620.1 - 0.18 12.1 11.8 9.9 6.5 2.1 3.9 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF148 PF02520.17 AAZ33620.1 - 0.68 10.1 14.6 0.18 11.9 2.8 3.3 2 1 0 2 2 2 0 Domain of unknown function DUF148 FixH PF05751.11 AAZ33620.1 - 0.78 9.7 4.6 0.31 11.0 0.5 2.4 2 0 0 2 2 2 0 FixH Vps53_N PF04100.12 AAZ33620.1 - 1.7 7.5 15.3 0.22 10.5 4.5 2.4 2 0 0 2 2 2 0 Vps53-like, N-terminal Folliculin PF11704.8 AAZ33620.1 - 2.3 8.1 17.2 0.21 11.4 3.2 2.8 2 1 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport DUF1664 PF07889.12 AAZ33620.1 - 4.3 7.4 16.5 1 9.4 3.0 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) HTH_psq PF05225.16 AAZ33620.1 - 5.4 6.8 7.6 0.49 10.2 1.2 2.5 2 0 0 2 2 2 0 helix-turn-helix, Psq domain LMBR1 PF04791.16 AAZ33620.1 - 8 5.2 13.5 6.9 5.4 5.9 2.4 2 1 0 2 2 2 0 LMBR1-like membrane protein Fib_alpha PF08702.10 AAZ33620.1 - 8.5 6.6 12.9 6.9 6.9 1.7 3.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family TMPIT PF07851.13 AAZ33620.1 - 8.6 5.5 10.6 12 5.0 2.6 2.5 2 0 0 2 2 2 0 TMPIT-like protein ISG65-75 PF11727.8 AAZ33620.1 - 9.4 5.4 17.3 0.044 13.0 1.5 3.0 3 0 0 3 3 3 0 Invariant surface glycoprotein FCD PF07729.12 AAZ33621.1 - 1.4e-21 77.2 8.6 2.3e-21 76.5 8.6 1.3 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 AAZ33621.1 - 1.5e-18 66.2 1.4 2e-18 65.8 0.2 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family MiaE PF06175.11 AAZ33622.1 - 1.4e-75 254.0 4.1 5.7e-61 206.2 1.8 2.0 1 1 1 2 2 2 2 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) SWI2_SNF2 PF18766.1 AAZ33623.1 - 9.3e-24 84.3 2.0 2.6e-23 82.9 1.6 2.1 1 1 0 1 1 1 1 SWI2/SNF2 ATPase ResIII PF04851.15 AAZ33623.1 - 5.3e-16 59.1 0.0 1.9e-15 57.3 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HSDR_N PF04313.14 AAZ33623.1 - 5.4e-12 46.1 0.0 1.4e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) DEAD PF00270.29 AAZ33623.1 - 5.1e-08 32.9 0.0 1.5e-07 31.3 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Aconitase PF00330.20 AAZ33624.1 - 9.8e-144 479.8 0.0 1.3e-143 479.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 AAZ33624.1 - 2.3e-27 95.9 0.0 4.8e-27 94.9 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain HemX PF04375.14 AAZ33625.1 - 0.00059 19.2 2.8 0.00069 19.0 2.8 1.0 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase ADIP PF11559.8 AAZ33625.1 - 0.0082 16.2 3.5 0.01 15.9 3.5 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF4407 PF14362.6 AAZ33625.1 - 0.0086 15.5 0.5 0.01 15.2 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Striatin PF08232.12 AAZ33625.1 - 0.015 15.9 1.6 0.015 15.9 1.6 1.4 1 1 1 2 2 2 0 Striatin family Uso1_p115_C PF04871.13 AAZ33625.1 - 0.11 12.9 6.5 0.14 12.5 6.5 1.1 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region TMF_DNA_bd PF12329.8 AAZ33625.1 - 0.35 10.9 8.2 0.52 10.4 8.2 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF2570 PF10828.8 AAZ33625.1 - 1.4 8.8 7.3 2.9 7.8 3.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) CALM_bind PF16025.5 AAZ33625.1 - 2.3 8.7 5.1 7.1 7.2 5.1 1.7 1 1 0 1 1 1 0 Calcium-dependent calmodulin binding DUF3509 PF12021.8 AAZ33626.1 - 5.4e-33 112.6 0.0 6.3e-33 112.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3509) 4HBT PF03061.22 AAZ33628.1 - 2.5e-12 46.9 0.0 3.2e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily Zn_Tnp_IS1595 PF12760.7 AAZ33629.1 - 0.033 14.2 0.4 0.056 13.4 0.4 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-MYND PF01753.18 AAZ33629.1 - 0.033 14.3 0.1 0.047 13.8 0.1 1.3 1 0 0 1 1 1 0 MYND finger XAF1_C PF18608.1 AAZ33629.1 - 0.041 13.4 0.1 0.051 13.1 0.1 1.3 1 0 0 1 1 1 0 XIAP-associated factor 1 C-terminal domain Metallothio_Pro PF02069.16 AAZ33629.1 - 0.058 13.6 0.1 0.077 13.2 0.1 1.1 1 0 0 1 1 1 0 Prokaryotic metallothionein Aminotran_3 PF00202.21 AAZ33630.1 - 9.3e-86 288.0 0.0 1.1e-85 287.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 AAZ33630.1 - 0.028 13.7 0.0 0.14 11.4 0.0 1.9 2 0 0 2 2 2 0 Beta-eliminating lyase Aminotran_1_2 PF00155.21 AAZ33630.1 - 0.041 13.1 0.0 0.18 10.9 0.0 1.9 2 1 1 3 3 3 0 Aminotransferase class I and II ABC_tran PF00005.27 AAZ33631.1 - 2.2e-33 115.6 0.0 4.2e-33 114.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter TOBE_2 PF08402.10 AAZ33631.1 - 1.4e-10 41.2 0.0 1.4e-09 37.9 0.0 2.7 3 0 0 3 3 3 1 TOBE domain OB_MalK PF17912.1 AAZ33631.1 - 2.5e-09 37.8 0.2 1.1e-08 35.8 0.0 2.3 2 0 0 2 2 1 1 MalK OB fold domain AAA_21 PF13304.6 AAZ33631.1 - 5e-07 29.8 0.1 0.00064 19.6 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system TOBE PF03459.17 AAZ33631.1 - 1.7e-05 25.0 0.0 0.00077 19.7 0.0 2.8 2 1 0 2 2 2 1 TOBE domain RsgA_GTPase PF03193.16 AAZ33631.1 - 4.8e-05 23.3 0.2 0.00028 20.8 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 AAZ33631.1 - 9.3e-05 22.0 0.1 0.0013 18.2 0.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain CysA_C_terminal PF17850.1 AAZ33631.1 - 0.00039 20.9 0.0 0.0017 18.9 0.0 2.2 1 0 0 1 1 1 1 CysA C-terminal regulatory domain AAA PF00004.29 AAZ33631.1 - 0.0007 20.0 0.0 0.0023 18.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AAZ33631.1 - 0.0012 19.3 0.2 0.0026 18.2 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 AAZ33631.1 - 0.0016 19.0 0.1 0.0027 18.2 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAZ33631.1 - 0.0045 16.7 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AAZ33631.1 - 0.0057 16.9 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 AAZ33631.1 - 0.011 15.7 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_33 PF13671.6 AAZ33631.1 - 0.017 15.3 0.0 0.037 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 AAZ33631.1 - 0.02 14.6 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 AAZ33631.1 - 0.022 14.9 0.0 0.056 13.5 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.6 AAZ33631.1 - 0.026 14.8 0.0 0.055 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 AAZ33631.1 - 0.078 12.2 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Myosin_N PF02736.19 AAZ33631.1 - 0.082 12.8 0.1 6.4 6.7 0.0 3.2 4 0 0 4 4 4 0 Myosin N-terminal SH3-like domain AAA_5 PF07728.14 AAZ33631.1 - 0.088 12.8 0.1 0.23 11.5 0.1 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 AAZ33631.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 AAZ33631.1 - 0.13 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 AAZ33631.1 - 0.14 12.6 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase CT_A_B PF02626.15 AAZ33632.1 - 1.6e-92 309.9 0.1 1.9e-92 309.7 0.1 1.0 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B HSP90 PF00183.18 AAZ33633.1 - 3.1e-133 445.4 0.0 9e-130 434.0 0.0 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c PF02518.26 AAZ33633.1 - 2.8e-12 47.1 0.1 5e-12 46.3 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 AAZ33633.1 - 1.1e-11 44.7 0.1 2.1e-11 43.8 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MCPsignal PF00015.21 AAZ33634.1 - 4.6e-36 124.2 19.8 4.6e-36 124.2 19.8 3.4 3 1 1 4 4 4 1 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AAZ33634.1 - 3.1e-10 40.3 0.2 3.1e-10 40.3 0.2 3.7 4 0 0 4 4 4 1 HAMP domain MA3 PF02847.17 AAZ33634.1 - 0.15 12.1 0.6 31 4.6 0.1 3.0 2 1 1 3 3 3 0 MA3 domain BLOC1_2 PF10046.9 AAZ33634.1 - 0.83 10.0 4.7 6.4 7.2 4.3 2.9 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3966 PF13110.6 AAZ33634.1 - 3.3 7.7 4.7 5.1 7.1 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3966) Bacillus_HBL PF05791.11 AAZ33634.1 - 8.2 6.2 10.6 5.2 6.9 4.4 3.1 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Methyltransf_25 PF13649.6 AAZ33635.1 - 3.5e-10 40.5 0.0 6.7e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAZ33635.1 - 2.3e-08 34.6 0.0 4e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAZ33635.1 - 6.6e-08 32.5 0.0 8.6e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAZ33635.1 - 2e-06 28.5 0.0 3.7e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 AAZ33635.1 - 2.7e-06 26.8 0.0 3.7e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 AAZ33635.1 - 6.3e-06 26.1 0.0 1.1e-05 25.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 AAZ33635.1 - 0.0089 15.6 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Rsm22 PF09243.10 AAZ33635.1 - 0.012 15.0 0.0 0.012 15.0 0.0 1.5 2 0 0 2 2 1 0 Mitochondrial small ribosomal subunit Rsm22 CheR PF01739.18 AAZ33635.1 - 0.059 12.9 0.0 4.3 6.8 0.0 2.2 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain FtsJ PF01728.19 AAZ33635.1 - 0.13 12.3 0.0 0.36 10.9 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 AAZ33635.1 - 0.18 11.8 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.16 AAZ33637.1 - 2.2e-49 168.3 45.1 2.2e-49 168.3 45.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily HemX PF04375.14 AAZ33638.1 - 2.2e-91 306.6 22.3 2.6e-91 306.4 22.3 1.0 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase DUF5516 PF17637.2 AAZ33638.1 - 0.74 9.6 3.2 1.5 8.6 3.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5516) Glycos_transf_4 PF00953.21 AAZ33639.1 - 1e-30 106.8 16.0 1e-30 106.8 16.0 2.2 2 1 0 2 2 2 1 Glycosyl transferase family 4 Sod_Cu PF00080.20 AAZ33640.1 - 1.8e-31 109.2 1.0 2.1e-31 109.0 1.0 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) DUF1615 PF07759.12 AAZ33641.1 - 5.1e-147 489.2 0.0 5.9e-147 489.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1615) PagL PF09411.10 AAZ33642.1 - 4.5e-40 136.9 2.0 5.8e-40 136.5 2.0 1.1 1 0 0 1 1 1 1 Lipid A 3-O-deacylase (PagL) OMP_b-brl PF13505.6 AAZ33642.1 - 0.0018 18.4 10.2 0.0035 17.5 10.2 1.4 1 1 0 1 1 1 1 Outer membrane protein beta-barrel domain LPAM_1 PF08139.12 AAZ33642.1 - 0.011 16.2 1.7 0.016 15.7 1.7 1.3 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Thioesterase PF00975.20 AAZ33643.1 - 2.1e-45 155.6 0.0 2.5e-45 155.4 0.0 1.0 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 AAZ33643.1 - 3.5e-07 31.1 0.6 4.3e-07 30.8 0.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAZ33643.1 - 0.00018 20.9 0.0 0.00037 19.8 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 AAZ33643.1 - 0.0076 16.1 0.0 0.01 15.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 AAZ33643.1 - 0.023 13.6 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme UPF0227 PF05728.12 AAZ33643.1 - 0.077 12.9 0.0 0.12 12.3 0.0 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) Lipase_3 PF01764.25 AAZ33643.1 - 0.09 12.6 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_1 PF00561.20 AAZ33643.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF4691 PF15762.5 AAZ33643.1 - 0.23 11.6 0.0 0.34 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4691) HATPase_c PF02518.26 AAZ33644.1 - 4.3e-15 56.2 0.0 9e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AAZ33644.1 - 7.9e-15 55.0 0.1 2.5e-14 53.4 0.0 1.9 2 0 0 2 2 2 1 Response regulator receiver domain GAF_2 PF13185.6 AAZ33644.1 - 1.7e-12 47.8 3.7 7.7e-06 26.2 0.2 3.1 3 0 0 3 3 3 2 GAF domain PAS_3 PF08447.12 AAZ33644.1 - 2.8e-10 40.3 0.0 5.5e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 PAS fold HisKA PF00512.25 AAZ33644.1 - 1.6e-09 37.7 0.5 9.3e-09 35.2 0.0 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.6 AAZ33644.1 - 6.7e-05 23.2 0.1 0.00051 20.4 0.0 2.6 3 0 0 3 3 3 1 GAF domain PAS PF00989.25 AAZ33644.1 - 0.0065 16.4 0.2 0.055 13.5 0.0 2.5 1 1 1 2 2 2 1 PAS fold DUF2218 PF09981.9 AAZ33644.1 - 0.056 13.8 0.2 0.056 13.8 0.2 2.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2218) HATPase_c_2 PF13581.6 AAZ33644.1 - 0.098 12.6 0.0 0.38 10.7 0.0 2.0 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain AI-2E_transport PF01594.16 AAZ33645.1 - 6.9e-09 35.3 35.7 1.9e-08 33.8 35.7 1.7 1 1 0 1 1 1 1 AI-2E family transporter IMS PF00817.20 AAZ33646.1 - 9.9e-53 178.2 0.0 1.4e-52 177.7 0.0 1.2 1 0 0 1 1 1 1 impB/mucB/samB family IMS_HHH PF11798.8 AAZ33646.1 - 8.2e-08 32.1 0.0 3.3e-07 30.2 0.0 2.1 1 0 0 1 1 1 1 IMS family HHH motif IMS_C PF11799.8 AAZ33646.1 - 0.0049 17.6 0.0 0.0088 16.7 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DNA_pol_lambd_f PF10391.9 AAZ33646.1 - 0.0089 15.8 0.0 0.023 14.5 0.0 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda Cdd1 PF11731.8 AAZ33646.1 - 0.046 14.0 0.0 0.096 12.9 0.0 1.4 1 0 0 1 1 1 0 Pathogenicity locus Pkinase PF00069.25 AAZ33647.1 - 1e-28 100.5 0.0 1.5e-28 99.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AAZ33647.1 - 2.1e-14 53.5 0.0 3.4e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PP2C_2 PF13672.6 AAZ33647.1 - 4.4e-08 33.0 1.8 8.5e-08 32.1 1.8 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C APH PF01636.23 AAZ33647.1 - 2e-05 24.6 3.0 2e-05 24.6 3.0 2.8 3 1 0 3 3 3 1 Phosphotransferase enzyme family PP2C PF00481.21 AAZ33647.1 - 0.00089 19.0 0.1 0.27 10.8 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C Kinase-like PF14531.6 AAZ33647.1 - 0.0017 17.7 0.0 0.01 15.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 AAZ33647.1 - 0.012 15.0 0.3 0.03 13.7 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family SpoIIE PF07228.12 AAZ33647.1 - 0.048 13.6 0.3 0.083 12.8 0.3 1.3 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) Pkinase_fungal PF17667.1 AAZ33647.1 - 0.21 10.3 0.0 0.32 9.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF350 PF03994.14 AAZ33648.1 - 1.3e-21 76.4 14.8 3.1e-12 46.4 0.8 2.2 2 0 0 2 2 2 2 Domain of Unknown Function (DUF350) FtsH_ext PF06480.15 AAZ33648.1 - 2.9 8.3 6.2 5 7.5 0.7 2.3 2 0 0 2 2 2 0 FtsH Extracellular VIT1 PF01988.19 AAZ33648.1 - 3.8 7.3 10.8 0.72 9.7 7.2 1.5 1 1 1 2 2 2 0 VIT family Transposase_mut PF00872.18 AAZ33649.1 - 1.5e-117 392.7 0.0 1.9e-117 392.3 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ33649.1 - 7.7e-05 23.0 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain DUF4844 PF16133.5 AAZ33649.1 - 0.23 12.0 0.0 0.55 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) T3SS_HrpK1 PF16937.5 AAZ33650.1 - 1.3e-96 323.3 14.0 1.3e-96 323.3 14.0 2.9 3 1 0 3 3 3 1 Type III secretion system translocator protein, HrpF HATPase_c PF02518.26 AAZ33651.1 - 3.3e-16 59.8 0.0 5.9e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAZ33651.1 - 1.8e-14 53.5 4.4 4.5e-14 52.2 4.4 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AAZ33651.1 - 5.8e-07 29.8 1.4 1.2e-06 28.8 0.0 2.3 3 0 0 3 3 3 1 HAMP domain HATPase_c_2 PF13581.6 AAZ33651.1 - 0.028 14.4 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain UDPG_MGDP_dh PF00984.19 AAZ33651.1 - 0.095 12.9 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain GidB PF02527.15 AAZ33652.1 - 3.2e-61 205.9 0.0 3.8e-61 205.6 0.0 1.0 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_31 PF13847.6 AAZ33652.1 - 0.00047 20.0 0.0 0.00095 19.0 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 AAZ33652.1 - 0.0019 17.8 0.0 0.0028 17.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 AAZ33652.1 - 0.066 12.9 0.0 0.092 12.5 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_25 PF13649.6 AAZ33652.1 - 0.076 13.7 0.0 0.57 10.9 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain RimM PF01782.18 AAZ33653.1 - 3.2e-25 88.1 0.0 6.4e-25 87.2 0.0 1.5 1 0 0 1 1 1 1 RimM N-terminal domain PRC PF05239.16 AAZ33653.1 - 3.8e-06 26.9 0.0 7.9e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 PRC-barrel domain ABC_tran PF00005.27 AAZ33655.1 - 5.5e-34 117.6 0.0 8.3e-34 117.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAZ33655.1 - 2.4e-12 47.3 0.0 2.8e-05 24.1 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAZ33655.1 - 6e-08 32.4 0.2 5.3e-06 26.0 0.2 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 AAZ33655.1 - 6.2e-05 22.9 0.0 0.0021 17.8 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 AAZ33655.1 - 0.00034 20.3 0.0 0.00067 19.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain APS_kinase PF01583.20 AAZ33655.1 - 0.0013 18.7 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_23 PF13476.6 AAZ33655.1 - 0.0049 17.4 0.3 0.0082 16.7 0.3 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAZ33655.1 - 0.0055 17.1 0.1 0.0096 16.3 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 AAZ33655.1 - 0.0081 15.9 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain G-alpha PF00503.20 AAZ33655.1 - 0.011 15.0 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_13 PF13166.6 AAZ33655.1 - 0.022 13.4 0.0 0.59 8.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 AAZ33655.1 - 0.024 14.8 0.1 0.055 13.6 0.1 2.0 1 1 1 2 2 2 0 AAA domain NACHT PF05729.12 AAZ33655.1 - 0.025 14.5 0.0 0.067 13.1 0.0 1.7 2 0 0 2 2 2 0 NACHT domain RsgA_GTPase PF03193.16 AAZ33655.1 - 0.025 14.5 0.1 0.04 13.8 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 AAZ33655.1 - 0.028 14.9 0.0 0.053 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AAZ33655.1 - 0.034 14.4 0.3 0.18 12.1 0.1 2.0 1 1 1 2 2 2 0 AAA domain ABC_ATPase PF09818.9 AAZ33655.1 - 0.035 12.9 0.0 4.6 5.9 0.0 2.5 2 1 0 2 2 2 0 Predicted ATPase of the ABC class Mg_chelatase PF01078.21 AAZ33655.1 - 0.054 12.9 0.0 0.095 12.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 AAZ33655.1 - 0.062 13.3 0.1 0.67 9.9 0.1 2.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 AAZ33655.1 - 0.081 12.6 0.1 0.28 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 AAZ33655.1 - 0.097 12.0 0.2 0.13 11.6 0.2 1.5 1 1 0 1 1 1 0 FtsK/SpoIIIE family PRK PF00485.18 AAZ33655.1 - 0.15 11.8 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_25 PF13481.6 AAZ33655.1 - 0.15 11.6 1.1 0.59 9.7 0.9 2.2 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 AAZ33655.1 - 0.25 11.5 3.2 1 9.6 0.3 2.6 2 1 0 3 3 3 0 AAA domain MethyltransfD12 PF02086.15 AAZ33657.1 - 2.1e-21 76.8 0.0 2.8e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase Baculo_RING PF05883.11 AAZ33657.1 - 2.7e-05 24.1 0.0 4.6e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Baculovirus U-box/Ring-like domain YscO PF07321.12 AAZ33658.1 - 4.4e-06 26.7 20.5 5.1e-06 26.5 20.5 1.1 1 0 0 1 1 1 1 Type III secretion protein YscO YscO-like PF16789.5 AAZ33658.1 - 0.0005 20.1 14.7 0.00058 19.9 14.7 1.0 1 0 0 1 1 1 1 YscO-like protein SAC3_GANP PF03399.16 AAZ33658.1 - 0.00081 18.9 4.9 0.00094 18.6 4.9 1.2 1 0 0 1 1 1 1 SAC3/GANP family KfrA_N PF11740.8 AAZ33658.1 - 0.82 10.4 16.9 0.3 11.8 4.6 2.3 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Amidohydro_1 PF01979.20 AAZ33659.1 - 1.8e-67 228.1 0.2 2.1e-67 227.9 0.2 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AAZ33659.1 - 5.1e-17 62.5 5.3 1.3e-15 57.9 1.1 2.1 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 AAZ33659.1 - 0.14 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Adenosine/AMP deaminase Usp PF00582.26 AAZ33660.1 - 3.2e-24 86.0 0.2 3.7e-24 85.8 0.2 1.1 1 0 0 1 1 1 1 Universal stress protein family NTP_transf_3 PF12804.7 AAZ33660.1 - 0.081 13.3 0.1 0.14 12.5 0.1 1.3 1 0 0 1 1 1 0 MobA-like NTP transferase domain ABC_tran PF00005.27 AAZ33661.1 - 1.7e-28 99.8 0.0 2.9e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter TOBE PF03459.17 AAZ33661.1 - 4.8e-14 52.4 0.2 2.4e-13 50.2 0.1 2.2 2 0 0 2 2 2 1 TOBE domain AAA_21 PF13304.6 AAZ33661.1 - 3.2e-06 27.2 1.1 0.034 14.0 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AAZ33661.1 - 0.00017 22.2 0.1 0.00025 21.6 0.1 1.2 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 AAZ33661.1 - 0.00079 18.9 0.0 0.35 10.3 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AAZ33661.1 - 0.00098 19.5 0.6 0.0042 17.5 0.6 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AAZ33661.1 - 0.0015 18.9 0.4 0.0046 17.2 0.1 1.9 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 AAZ33661.1 - 0.011 16.0 0.0 0.28 11.4 0.0 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 AAZ33661.1 - 0.012 15.4 0.1 0.023 14.5 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 AAZ33661.1 - 0.066 12.9 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 AAZ33661.1 - 0.088 12.2 0.0 0.59 9.5 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein AAA_33 PF13671.6 AAZ33661.1 - 0.12 12.6 0.0 0.28 11.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain BPD_transp_2 PF02653.16 AAZ33662.1 - 2.5e-51 174.4 38.9 2.5e-51 174.4 38.9 1.6 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component ABC_tran PF00005.27 AAZ33662.1 - 4.6e-21 75.8 0.0 1.2e-20 74.4 0.0 1.8 1 0 0 1 1 1 1 ABC transporter PspB PF06667.12 AAZ33662.1 - 0.029 14.4 0.1 0.079 13.0 0.1 1.8 1 0 0 1 1 1 0 Phage shock protein B SpoIISA_toxin PF14171.6 AAZ33662.1 - 5.9 6.5 5.5 0.73 9.5 0.5 1.8 2 0 0 2 2 2 0 Toxin SpoIISA, type II toxin-antitoxin system Transket_pyr PF02779.24 AAZ33663.1 - 2.1e-65 219.8 0.0 4e-65 218.8 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 AAZ33663.1 - 2.4e-54 183.2 0.0 4.4e-54 182.3 0.0 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 AAZ33663.1 - 2.1e-53 181.2 0.0 3.7e-53 180.4 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component 2-oxogl_dehyd_N PF16078.5 AAZ33663.1 - 1.1e-17 63.3 0.1 2.4e-17 62.2 0.1 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus Glyco_hydro_1 PF00232.18 AAZ33664.1 - 0.0003 19.4 0.0 0.02 13.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 1 Glyco_hydro_42 PF02449.15 AAZ33664.1 - 0.0085 15.5 0.0 0.018 14.4 0.0 1.5 1 1 0 1 1 1 1 Beta-galactosidase Glyco_hydr_30_2 PF14587.6 AAZ33664.1 - 0.0089 15.7 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 Glyco_hydro_53 PF07745.13 AAZ33664.1 - 0.14 11.1 0.0 0.37 9.7 0.0 1.6 2 0 0 2 2 2 0 Glycosyl hydrolase family 53 G_glu_transpept PF01019.21 AAZ33665.1 - 5e-150 500.7 0.3 5.7e-150 500.5 0.3 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase MS_channel PF00924.18 AAZ33667.1 - 8.4e-45 152.9 2.8 1.4e-44 152.1 2.8 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel Cas_Csa4 PF09703.10 AAZ33667.1 - 0.033 13.5 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa4) Molybdopterin PF00384.22 AAZ33668.1 - 3.1e-22 79.2 0.0 1.5e-11 43.9 0.0 2.0 2 0 0 2 2 2 2 Molybdopterin oxidoreductase DUF1127 PF06568.11 AAZ33668.1 - 0.094 12.5 0.0 0.28 10.9 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1127) PdxJ PF03740.13 AAZ33669.1 - 2.2e-99 331.3 3.5 2.5e-99 331.1 3.5 1.0 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthesis protein PdxJ AP_endonuc_2 PF01261.24 AAZ33669.1 - 0.0082 15.6 1.4 0.081 12.4 1.4 2.8 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel Glyco_trans_4_4 PF13579.6 AAZ33669.1 - 0.14 12.6 3.5 0.12 12.8 0.7 2.1 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain Flg_bbr_C PF06429.13 AAZ33670.1 - 4.8e-09 36.2 3.5 5.2e-09 36.1 0.8 2.7 2 0 0 2 2 2 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 AAZ33670.1 - 5.4e-05 23.0 7.8 0.00017 21.4 6.3 2.9 2 0 0 2 2 2 1 Flagella basal body rod protein Baculo_PEP_C PF04513.12 AAZ33670.1 - 0.011 15.8 14.6 0.026 14.6 13.1 2.5 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3450 PF11932.8 AAZ33670.1 - 0.027 13.8 2.1 0.056 12.7 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Lant_dehydr_C PF14028.6 AAZ33670.1 - 0.037 13.6 0.6 0.059 12.9 0.6 1.2 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term AAA_13 PF13166.6 AAZ33670.1 - 0.048 12.3 0.9 0.07 11.8 0.9 1.1 1 0 0 1 1 1 0 AAA domain IFT57 PF10498.9 AAZ33670.1 - 0.13 11.2 0.4 0.21 10.5 0.4 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Lectin_N PF03954.14 AAZ33670.1 - 0.13 12.0 1.9 0.32 10.8 1.9 1.6 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain KxDL PF10241.9 AAZ33670.1 - 0.48 10.7 4.7 1.6 9.1 4.7 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein DUF148 PF02520.17 AAZ33670.1 - 0.71 10.0 6.1 18 5.5 0.1 2.5 1 1 1 2 2 2 0 Domain of unknown function DUF148 Cluap1 PF10234.9 AAZ33670.1 - 0.97 8.8 4.4 0.3 10.4 0.6 2.0 3 0 0 3 3 3 0 Clusterin-associated protein-1 DotU PF09850.9 AAZ33671.1 - 1.4e-52 178.4 1.0 1.7e-52 178.1 1.0 1.1 1 0 0 1 1 1 1 Type VI secretion system protein DotU His_biosynth PF00977.21 AAZ33672.1 - 1.4e-91 306.1 0.4 1.6e-91 305.9 0.4 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein NMO PF03060.15 AAZ33672.1 - 5.1e-07 29.4 7.2 0.0017 17.8 2.2 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase ThiG PF05690.14 AAZ33672.1 - 2.1e-06 27.2 2.2 0.0051 16.1 0.1 2.1 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 AAZ33672.1 - 3.6e-06 26.4 0.5 0.00024 20.4 0.0 2.1 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase G3P_antiterm PF04309.12 AAZ33672.1 - 0.00011 21.6 0.3 0.0047 16.3 0.0 2.1 2 0 0 2 2 2 1 Glycerol-3-phosphate responsive antiterminator TMP-TENI PF02581.17 AAZ33672.1 - 0.00018 20.9 0.2 0.38 10.1 0.0 2.2 2 0 0 2 2 2 2 Thiamine monophosphate synthase Dus PF01207.17 AAZ33672.1 - 0.0002 20.6 0.2 0.0032 16.6 0.1 2.1 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) IMPDH PF00478.25 AAZ33672.1 - 0.0019 17.3 1.7 0.17 10.9 0.0 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain IGPS PF00218.21 AAZ33672.1 - 0.023 13.9 0.0 0.068 12.3 0.0 1.7 1 1 1 2 2 2 0 Indole-3-glycerol phosphate synthase PE PF00934.20 AAZ33672.1 - 0.058 13.7 0.4 0.17 12.2 0.0 1.9 2 0 0 2 2 2 0 PE family FMN_dh PF01070.18 AAZ33672.1 - 0.064 12.3 0.2 0.064 12.3 0.2 1.6 2 0 0 2 2 2 0 FMN-dependent dehydrogenase FecCD PF01032.18 AAZ33673.1 - 1.8e-89 299.8 43.7 2.2e-89 299.6 43.7 1.0 1 0 0 1 1 1 1 FecCD transport family ABC-3 PF00950.17 AAZ33673.1 - 1.8e-07 31.0 27.4 1.8e-07 31.0 27.4 2.0 2 1 0 2 2 2 1 ABC 3 transport family GspH PF12019.8 AAZ33674.1 - 1.3e-17 64.1 0.4 1.7e-17 63.8 0.4 1.1 1 0 0 1 1 1 1 Type II transport protein GspH N_methyl PF07963.12 AAZ33674.1 - 2.2e-07 30.2 2.5 4.2e-07 29.2 2.5 1.5 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif Gly_kinase PF02595.15 AAZ33675.1 - 8.9e-147 488.9 4.4 1e-146 488.7 4.4 1.0 1 0 0 1 1 1 1 Glycerate kinase family TPP_enzyme_N PF02776.18 AAZ33676.1 - 8.9e-60 201.2 0.3 1.3e-58 197.4 0.3 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 AAZ33676.1 - 3.9e-51 172.8 1.2 2.5e-49 167.0 0.0 3.0 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 AAZ33676.1 - 2.4e-46 156.9 0.1 5e-46 155.8 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 AAZ33676.1 - 0.0051 16.6 0.1 0.0079 16.0 0.1 1.3 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg ROQ_II PF18386.1 AAZ33676.1 - 0.13 12.1 0.1 0.26 11.2 0.1 1.5 1 0 0 1 1 1 0 Roquin II domain Coatomer_b_Cpla PF14806.6 AAZ33676.1 - 0.13 12.2 0.1 0.27 11.2 0.1 1.5 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform MgsA_C PF12002.8 AAZ33677.1 - 3e-69 232.2 0.0 4.5e-69 231.7 0.0 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 AAZ33677.1 - 7.3e-22 77.5 0.1 1.3e-20 73.5 0.1 2.4 2 0 0 2 2 2 1 AAA C-terminal domain AAA PF00004.29 AAZ33677.1 - 8.6e-16 58.6 0.0 1.5e-15 57.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 AAZ33677.1 - 2.4e-14 53.4 0.0 4.3e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 AAZ33677.1 - 4.6e-07 29.9 0.0 3.3e-06 27.2 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AAZ33677.1 - 3.5e-06 27.5 0.6 0.0016 18.8 0.0 3.1 2 1 1 3 3 3 1 AAA ATPase domain Mg_chelatase PF01078.21 AAZ33677.1 - 9.2e-06 25.2 0.1 0.0035 16.7 0.1 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 AAZ33677.1 - 3.2e-05 24.2 0.3 0.022 15.0 0.0 3.1 1 1 2 3 3 3 1 AAA domain Sigma54_activat PF00158.26 AAZ33677.1 - 8.1e-05 22.4 0.0 0.036 13.8 0.0 2.3 1 1 0 2 2 2 1 Sigma-54 interaction domain AAA_33 PF13671.6 AAZ33677.1 - 0.00017 21.7 0.0 0.00031 20.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 AAZ33677.1 - 0.00021 21.5 0.0 0.00037 20.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 AAZ33677.1 - 0.00056 19.9 0.0 0.0014 18.7 0.0 1.6 2 0 0 2 2 1 1 AAA domain ATPase_2 PF01637.18 AAZ33677.1 - 0.0015 18.5 0.0 0.55 10.1 0.0 2.4 1 1 1 2 2 2 2 ATPase domain predominantly from Archaea AAA_18 PF13238.6 AAZ33677.1 - 0.0015 19.1 0.0 0.0052 17.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 AAZ33677.1 - 0.0016 18.2 0.0 0.0036 17.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RsgA_GTPase PF03193.16 AAZ33677.1 - 0.002 18.1 0.0 0.0039 17.1 0.0 1.5 1 1 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 AAZ33677.1 - 0.0024 17.6 0.0 0.03 14.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 AAZ33677.1 - 0.0036 17.2 0.0 0.0079 16.1 0.0 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 AAZ33677.1 - 0.0042 16.9 0.0 2.6 7.8 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit ResIII PF04851.15 AAZ33677.1 - 0.006 16.6 0.0 0.59 10.1 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_24 PF13479.6 AAZ33677.1 - 0.01 15.6 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 AAZ33677.1 - 0.012 15.9 0.0 0.065 13.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 AAZ33677.1 - 0.015 15.8 0.0 0.028 15.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 AAZ33677.1 - 0.022 15.1 0.0 0.042 14.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 AAZ33677.1 - 0.035 14.4 0.1 11 6.3 0.0 2.3 1 1 1 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 AAZ33677.1 - 0.035 14.2 0.0 0.065 13.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_17 PF13207.6 AAZ33677.1 - 0.083 13.3 0.0 0.26 11.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 AAZ33677.1 - 0.14 11.6 0.0 3 7.2 0.0 2.5 1 1 2 3 3 3 0 Bacterial TniB protein DUF815 PF05673.13 AAZ33677.1 - 0.15 11.2 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Transposase_20 PF02371.16 AAZ33677.1 - 0.15 12.4 0.0 0.61 10.4 0.0 2.1 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family NB-ARC PF00931.22 AAZ33677.1 - 0.16 11.1 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_7 PF12775.7 AAZ33677.1 - 0.21 11.1 0.0 0.81 9.2 0.0 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region CBM_48 PF02922.18 AAZ33678.1 - 1.7e-27 95.6 0.0 6.2e-23 81.0 0.0 2.8 2 0 0 2 2 2 2 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase_C PF02806.18 AAZ33678.1 - 1.6e-22 79.8 0.0 3.2e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 AAZ33678.1 - 6.2e-12 45.7 0.0 2.9e-08 33.6 0.0 2.4 1 1 1 2 2 2 2 Alpha amylase, catalytic domain AMPK1_CBM PF16561.5 AAZ33678.1 - 0.0046 17.2 3.7 0.068 13.4 0.0 3.2 3 0 0 3 3 3 1 Glycogen recognition site of AMP-activated protein kinase Glyco_hydro_70 PF02324.16 AAZ33678.1 - 0.31 9.2 0.0 0.47 8.6 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 70 KinB_sensor PF16767.5 AAZ33679.1 - 4e-39 133.8 12.1 6e-38 130.0 3.2 3.3 2 1 1 3 3 3 2 Sensor domain of alginate biosynthesis sensor protein KinB HATPase_c PF02518.26 AAZ33679.1 - 6.3e-25 87.9 0.0 1.3e-24 86.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_4 PF08448.10 AAZ33679.1 - 6.6e-13 48.9 0.3 5.3e-12 46.0 0.1 2.4 2 0 0 2 2 2 1 PAS fold HisKA PF00512.25 AAZ33679.1 - 4.5e-12 45.8 0.4 4.5e-12 45.8 0.4 3.9 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AAZ33679.1 - 3e-10 40.3 1.4 7.3e-10 39.1 0.4 2.3 2 0 0 2 2 2 1 HAMP domain PAS PF00989.25 AAZ33679.1 - 1e-09 38.4 0.1 6.9e-09 35.7 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 AAZ33679.1 - 1.3e-07 31.5 0.4 1.6e-06 28.0 0.1 2.7 2 0 0 2 2 2 1 PAS domain HATPase_c_5 PF14501.6 AAZ33679.1 - 9.1e-06 25.5 0.0 1.9e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 GHKL domain PAS_9 PF13426.7 AAZ33679.1 - 1.1e-05 25.6 0.0 2.7e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_10 PF13596.6 AAZ33679.1 - 0.00096 19.7 0.0 0.0027 18.3 0.0 1.8 1 0 0 1 1 1 1 PAS domain HATPase_c_3 PF13589.6 AAZ33679.1 - 0.023 14.5 0.0 0.049 13.5 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 4HB_MCP_1 PF12729.7 AAZ33679.1 - 0.029 13.9 5.3 0.47 10.0 2.7 2.7 2 1 0 2 2 2 0 Four helix bundle sensory module for signal transduction HATPase_c_2 PF13581.6 AAZ33679.1 - 0.032 14.2 0.0 0.083 12.9 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain PAS_7 PF12860.7 AAZ33679.1 - 0.12 12.5 0.4 8.5 6.6 0.0 3.2 3 0 0 3 3 3 0 PAS fold SBP_bac_3 PF00497.20 AAZ33680.1 - 7.4e-46 156.4 0.0 9.3e-46 156.1 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1 PF09084.11 AAZ33680.1 - 0.00023 21.2 0.0 0.00052 20.0 0.0 1.6 1 1 0 1 1 1 1 NMT1/THI5 like Lig_chan-Glu_bd PF10613.9 AAZ33680.1 - 0.0062 16.7 0.0 0.017 15.3 0.0 1.8 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Phosphonate-bd PF12974.7 AAZ33680.1 - 0.026 14.1 0.0 1.1 8.8 0.0 2.7 2 1 0 2 2 2 0 ABC transporter, phosphonate, periplasmic substrate-binding protein YycC PF14174.6 AAZ33680.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 YycC-like protein GntR PF00392.21 AAZ33681.1 - 4.6e-16 58.2 3.1 9.2e-16 57.3 3.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family FCD PF07729.12 AAZ33681.1 - 2.9e-07 30.9 0.4 5.3e-07 30.1 0.1 1.6 2 0 0 2 2 2 1 FCD domain HOIP-UBA PF16678.5 AAZ33681.1 - 0.062 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 HOIP UBA domain pair Fe_dep_repress PF01325.19 AAZ33681.1 - 0.064 13.5 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain BolA PF01722.18 AAZ33682.1 - 5.2e-08 33.0 0.0 6.1e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein LysR_substrate PF03466.20 AAZ33683.1 - 4.1e-37 127.6 0.3 5.7e-37 127.1 0.3 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ33683.1 - 1.3e-17 63.5 0.4 2.2e-17 62.7 0.4 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_20 PF12840.7 AAZ33683.1 - 0.0014 18.6 0.4 0.0038 17.3 0.4 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 AAZ33683.1 - 0.025 14.5 0.5 0.072 13.0 0.5 1.7 1 0 0 1 1 1 0 MarR family HTH_23 PF13384.6 AAZ33683.1 - 0.13 12.1 0.1 0.31 10.9 0.1 1.6 1 0 0 1 1 1 0 Homeodomain-like domain DUF2153 PF09921.9 AAZ33683.1 - 0.15 11.9 0.3 9.1 6.1 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2153) HTH_5 PF01022.20 AAZ33683.1 - 0.28 11.1 2.7 0.51 10.2 1.5 2.0 1 1 0 1 1 1 0 Bacterial regulatory protein, arsR family C-C_Bond_Lyase PF15617.6 AAZ33686.1 - 5.2e-98 328.3 0.0 1.2e-97 327.1 0.0 1.5 1 1 0 1 1 1 1 C-C_Bond_Lyase of the TIM-Barrel fold HpcH_HpaI PF03328.14 AAZ33686.1 - 0.0058 15.8 0.1 0.033 13.3 0.1 2.0 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family DUF150 PF02576.17 AAZ33687.1 - 1.9e-30 105.1 0.1 3.6e-30 104.2 0.1 1.5 1 0 0 1 1 1 1 RimP N-terminal domain DUF150_C PF17384.2 AAZ33687.1 - 2.3e-18 66.1 0.1 3.7e-18 65.4 0.1 1.3 1 0 0 1 1 1 1 RimP C-terminal SH3 domain DUF839 PF05787.13 AAZ33688.1 - 9.4e-186 619.0 2.4 1.1e-185 618.8 2.4 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF839) TAT_signal PF10518.9 AAZ33688.1 - 0.24 11.3 3.5 0.6 10.0 3.5 1.7 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Glyco_hydro_3_C PF01915.22 AAZ33689.1 - 1.8e-52 178.3 0.0 9.3e-52 175.9 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 AAZ33689.1 - 6.7e-40 137.4 0.0 1.3e-39 136.4 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain PA14 PF07691.12 AAZ33689.1 - 4.9e-35 120.5 0.0 8.2e-35 119.8 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Fn3-like PF14310.6 AAZ33689.1 - 2.7e-24 85.1 3.5 5.3e-24 84.1 0.3 3.2 5 0 0 5 5 5 1 Fibronectin type III-like domain RHS PF03527.14 AAZ33690.1 - 3.4e-22 77.9 0.9 8.8e-20 70.2 0.2 2.8 2 0 0 2 2 2 2 RHS protein RHS_repeat PF05593.14 AAZ33690.1 - 3.1e-09 37.2 10.5 0.07 13.7 0.4 6.2 3 2 3 6 6 6 5 RHS Repeat Imm71 PF15602.6 AAZ33690.1 - 0.019 15.1 0.3 0.43 10.6 0.0 2.3 1 1 0 2 2 2 0 Immunity protein 71 DUF4585 PF15232.6 AAZ33690.1 - 0.12 12.4 0.7 0.26 11.3 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4585) DUF4595 PF15283.6 AAZ33690.1 - 0.13 12.3 4.2 0.5 10.4 1.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4595) with porin-like fold CPSase_L_D2 PF02786.17 AAZ33691.1 - 2.5e-109 363.7 0.1 8e-72 241.2 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 AAZ33691.1 - 1.2e-38 132.2 0.0 2.6e-38 131.1 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain MGS PF02142.22 AAZ33691.1 - 2.6e-21 75.6 0.4 2.6e-20 72.4 0.4 2.8 2 0 0 2 2 2 1 MGS-like domain ATP-grasp PF02222.22 AAZ33691.1 - 3.1e-18 65.9 0.0 1.8e-11 43.9 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.14 AAZ33691.1 - 1e-13 51.7 0.1 8.1e-09 35.7 0.0 2.7 3 0 0 3 3 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 AAZ33691.1 - 2.3e-11 43.6 0.0 1.9e-06 27.6 0.0 2.3 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 AAZ33691.1 - 3.6e-10 39.7 0.0 1.9e-06 27.7 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.6 AAZ33691.1 - 1.3e-07 31.3 0.0 0.011 15.3 0.0 4.0 3 1 0 3 3 3 2 ATP-grasp domain RimK PF08443.11 AAZ33691.1 - 7.7e-06 25.6 0.0 0.13 11.8 0.0 3.1 3 0 0 3 3 3 2 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.6 AAZ33691.1 - 0.00032 20.2 0.0 0.1 12.1 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain CoA_binding_2 PF13380.6 AAZ33691.1 - 0.00091 19.7 0.1 3.9 8.0 0.0 4.1 4 1 0 4 4 4 1 CoA binding domain B12-binding PF02310.19 AAZ33691.1 - 0.0051 16.8 1.9 10 6.2 0.0 4.4 5 1 1 6 6 6 2 B12 binding domain ATP-grasp_2 PF08442.10 AAZ33691.1 - 0.0096 15.5 0.0 1.8 8.1 0.0 3.1 3 0 0 3 3 3 1 ATP-grasp domain Isochorismatase PF00857.20 AAZ33691.1 - 0.048 13.8 0.7 1.5 8.9 0.1 3.1 3 0 0 3 3 3 0 Isochorismatase family EAL PF00563.20 AAZ33692.1 - 2.2e-75 253.2 0.0 2.2e-75 253.2 0.0 2.4 4 0 0 4 4 4 1 EAL domain GGDEF PF00990.21 AAZ33692.1 - 9e-41 139.3 0.8 2e-40 138.1 0.1 1.9 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain PAS_9 PF13426.7 AAZ33692.1 - 2e-13 50.5 0.0 4.9e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 PAS domain GAF PF01590.26 AAZ33692.1 - 8.1e-13 49.2 0.0 2.4e-12 47.6 0.0 1.9 2 0 0 2 2 2 1 GAF domain PAS PF00989.25 AAZ33692.1 - 6.4e-10 39.0 0.0 2.7e-08 33.8 0.0 2.6 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 AAZ33692.1 - 4.3e-09 36.5 0.0 2.5e-06 27.7 0.0 2.6 2 0 0 2 2 2 2 PAS fold GAF_2 PF13185.6 AAZ33692.1 - 1.2e-07 32.1 0.0 2.8e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 GAF domain PAS_4 PF08448.10 AAZ33692.1 - 1.5e-06 28.5 0.0 1.3e-05 25.4 0.0 2.5 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 AAZ33692.1 - 1.6e-05 24.8 0.0 0.00013 21.8 0.0 2.4 2 0 0 2 2 2 1 PAS domain GAF_3 PF13492.6 AAZ33692.1 - 0.0027 18.1 0.0 0.0069 16.7 0.0 1.7 1 0 0 1 1 1 1 GAF domain Pertactin PF03212.14 AAZ33692.1 - 0.044 13.7 0.5 0.32 11.0 0.0 2.5 3 0 0 3 3 3 0 Pertactin MltA PF03562.17 AAZ33693.1 - 1e-76 257.6 0.0 1.3e-76 257.3 0.0 1.1 1 0 0 1 1 1 1 MltA specific insert domain 3D PF06725.11 AAZ33693.1 - 2.9e-23 81.8 0.0 5.7e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 3D domain DcrB PF08786.11 AAZ33694.1 - 7.1e-20 71.4 0.0 8.9e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 DcrB DUF2220 PF09983.9 AAZ33694.1 - 0.12 11.8 1.7 0.53 9.6 0.5 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) ADH_zinc_N_2 PF13602.6 AAZ33695.1 - 5.4e-22 79.3 0.1 9.6e-22 78.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 AAZ33695.1 - 3.1e-11 43.4 0.0 1e-10 41.7 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AAZ33695.1 - 5.2e-08 32.7 0.0 8.3e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.21 AAZ33695.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family SPOUT_MTase PF02590.17 AAZ33696.1 - 5.2e-46 156.4 0.0 5.8e-46 156.3 0.0 1.0 1 0 0 1 1 1 1 Predicted SPOUT methyltransferase HTH_20 PF12840.7 AAZ33697.1 - 2.3e-18 66.0 0.0 3.6e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 AAZ33697.1 - 3.4e-08 33.2 0.2 4.9e-07 29.5 0.1 2.2 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 AAZ33697.1 - 0.00014 21.7 0.2 0.00026 20.8 0.2 1.5 1 1 0 1 1 1 1 MarR family HTH_IclR PF09339.10 AAZ33697.1 - 0.00015 21.5 0.1 0.00031 20.5 0.1 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_40 PF14493.6 AAZ33697.1 - 0.00061 20.2 0.0 0.0012 19.3 0.0 1.4 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 AAZ33697.1 - 0.00062 19.3 0.0 0.0015 18.0 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 AAZ33697.1 - 0.002 18.0 0.0 0.0025 17.8 0.0 1.3 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain MarR PF01047.22 AAZ33697.1 - 0.0024 17.8 0.0 0.0039 17.1 0.0 1.4 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.20 AAZ33697.1 - 0.0042 17.4 0.1 0.0088 16.4 0.0 1.6 2 0 0 2 2 1 1 Transcriptional regulator RP-C PF03428.13 AAZ33697.1 - 0.005 16.5 0.0 0.0069 16.0 0.0 1.3 1 0 0 1 1 1 1 Replication protein C N-terminal domain SAP130_C PF16014.5 AAZ33697.1 - 0.013 14.6 0.0 0.016 14.3 0.0 1.0 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus LexA_DNA_bind PF01726.16 AAZ33697.1 - 0.014 15.2 0.1 0.054 13.3 0.1 2.0 1 1 0 1 1 1 0 LexA DNA binding domain DUF2513 PF10711.9 AAZ33697.1 - 0.031 14.6 0.0 0.04 14.2 0.0 1.2 1 0 0 1 1 1 0 Hypothetical protein (DUF2513) HTH_11 PF08279.12 AAZ33697.1 - 0.033 14.1 0.1 0.11 12.4 0.1 1.9 1 1 1 2 2 2 0 HTH domain DUF4423 PF14394.6 AAZ33697.1 - 0.043 13.5 0.0 0.057 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) HTH_46 PF15977.5 AAZ33697.1 - 0.051 13.6 0.0 0.076 13.0 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA binding HTH_36 PF13730.6 AAZ33697.1 - 0.071 13.1 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_CodY PF08222.11 AAZ33697.1 - 0.087 12.4 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 CodY helix-turn-helix domain Mnd1 PF03962.15 AAZ33697.1 - 0.095 13.0 0.0 0.42 10.9 0.0 1.9 2 0 0 2 2 2 0 Mnd1 HTH domain TrmB PF01978.19 AAZ33697.1 - 0.099 12.5 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DprA_WH PF17782.1 AAZ33697.1 - 0.12 12.6 0.3 1.6 8.9 0.0 2.2 2 0 0 2 2 2 0 DprA winged helix domain Penicillinase_R PF03965.16 AAZ33697.1 - 0.12 12.7 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 Penicillinase repressor HTH_34 PF13601.6 AAZ33697.1 - 0.12 12.5 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain Molybdopterin PF00384.22 AAZ33698.1 - 3.9e-29 101.9 0.0 2.2e-28 99.4 0.0 2.1 2 1 0 2 2 2 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 AAZ33698.1 - 5.6e-05 23.1 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain E1-E2_ATPase PF00122.20 AAZ33699.1 - 7.5e-33 113.6 0.5 1.6e-32 112.5 0.5 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 AAZ33699.1 - 3e-18 66.9 0.1 9.4e-18 65.3 0.1 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AAZ33699.1 - 3.3e-05 24.4 0.0 8.6e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DNA_photolyase PF00875.18 AAZ33699.1 - 0.14 12.2 0.1 0.45 10.5 0.0 1.8 2 0 0 2 2 2 0 DNA photolyase DUF872 PF05915.12 AAZ33699.1 - 0.23 11.7 1.8 0.45 10.7 1.8 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) BPD_transp_1 PF00528.22 AAZ33700.1 - 5.2e-22 78.5 14.2 1.1e-21 77.4 11.2 2.4 2 1 1 3 3 3 2 Binding-protein-dependent transport system inner membrane component Transposase_mut PF00872.18 AAZ33701.1 - 5.4e-116 387.6 0.0 6.7e-116 387.3 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ33701.1 - 7.7e-05 23.0 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain DUF4844 PF16133.5 AAZ33701.1 - 0.23 12.0 0.0 0.55 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) TM_helix PF05552.12 AAZ33702.1 - 1.6e-20 72.8 12.1 6.8e-12 45.2 4.5 3.2 3 0 0 3 3 3 2 Conserved TM helix MS_channel PF00924.18 AAZ33702.1 - 3.8e-08 33.1 5.4 3.8e-08 33.1 5.4 2.7 3 0 0 3 3 3 1 Mechanosensitive ion channel Methyltransf_24 PF13578.6 AAZ33703.1 - 1.9e-08 35.3 0.0 3.7e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 AAZ33703.1 - 8.1e-06 26.1 0.0 1.6e-05 25.1 0.0 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase CmcI PF04989.12 AAZ33703.1 - 0.00068 19.4 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 Cephalosporin hydroxylase Methyltransf_25 PF13649.6 AAZ33703.1 - 0.029 15.1 0.0 0.083 13.6 0.0 1.8 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_3 PF01596.17 AAZ33703.1 - 0.19 10.9 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase adh_short_C2 PF13561.6 AAZ33704.1 - 4.4e-63 213.0 2.3 5.3e-63 212.7 2.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAZ33704.1 - 6.9e-54 182.3 1.6 8.2e-54 182.0 1.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAZ33704.1 - 2e-07 31.1 0.9 2.5e-07 30.8 0.9 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AAZ33704.1 - 0.038 13.4 0.2 0.13 11.7 0.2 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 AAZ33704.1 - 0.044 13.1 0.3 0.11 11.8 0.4 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glucokinase PF02685.16 AAZ33706.1 - 5.9e-108 360.6 0.0 6.6e-108 360.4 0.0 1.0 1 0 0 1 1 1 1 Glucokinase MMPL PF03176.15 AAZ33707.1 - 0.00051 19.1 14.4 0.00051 19.1 14.4 3.4 2 2 0 2 2 2 1 MMPL family Sterol-sensing PF12349.8 AAZ33707.1 - 0.0078 16.1 3.6 1.9 8.3 0.8 2.8 2 1 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation Transposase_mut PF00872.18 AAZ33708.1 - 1.4e-116 389.5 0.0 1.8e-116 389.2 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ33708.1 - 7.7e-05 23.0 0.0 0.00021 21.6 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain DUF4844 PF16133.5 AAZ33708.1 - 0.23 12.0 0.0 0.55 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) Sigma54_activat PF00158.26 AAZ33709.1 - 2.6e-63 212.7 0.0 3.7e-63 212.2 0.0 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AAZ33709.1 - 5e-22 78.5 0.0 1.2e-21 77.3 0.0 1.6 1 1 0 1 1 1 1 Sigma-54 interaction domain PAS_4 PF08448.10 AAZ33709.1 - 1.9e-20 73.1 0.7 8.2e-19 67.9 0.3 2.5 2 0 0 2 2 2 1 PAS fold HTH_8 PF02954.19 AAZ33709.1 - 7.6e-09 35.2 1.1 1.6e-08 34.2 1.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 AAZ33709.1 - 3.9e-07 30.1 0.0 1.1e-06 28.7 0.0 1.8 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AAZ33709.1 - 0.00031 21.2 0.5 0.00068 20.1 0.5 1.7 1 1 0 1 1 1 1 AAA ATPase domain HTH_28 PF13518.6 AAZ33709.1 - 0.00061 19.9 0.1 0.0015 18.6 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain Mg_chelatase PF01078.21 AAZ33709.1 - 0.00073 19.0 0.2 0.5 9.7 0.0 2.2 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI HTH_23 PF13384.6 AAZ33709.1 - 0.00098 18.9 0.1 0.0023 17.7 0.1 1.6 1 0 0 1 1 1 1 Homeodomain-like domain AAA_2 PF07724.14 AAZ33709.1 - 0.0015 18.6 0.0 0.0031 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 AAZ33709.1 - 0.0017 18.7 0.0 0.0031 17.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) HTH_Tnp_ISL3 PF13542.6 AAZ33709.1 - 0.003 16.9 0.0 0.0067 15.8 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_AsnC-type PF13404.6 AAZ33709.1 - 0.0047 16.7 3.2 0.012 15.5 1.6 2.3 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain PAS_9 PF13426.7 AAZ33709.1 - 0.0053 17.0 0.0 0.016 15.5 0.0 1.8 1 0 0 1 1 1 1 PAS domain RWP-RK PF02042.15 AAZ33709.1 - 0.0075 16.2 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 RWP-RK domain PAS PF00989.25 AAZ33709.1 - 0.0088 16.0 0.0 0.026 14.5 0.0 1.8 1 0 0 1 1 1 1 PAS fold HTH_11 PF08279.12 AAZ33709.1 - 0.0092 15.9 0.0 0.024 14.6 0.0 1.7 1 0 0 1 1 1 1 HTH domain HTH_24 PF13412.6 AAZ33709.1 - 0.012 15.2 0.9 0.035 13.7 0.4 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 AAZ33709.1 - 0.012 15.7 0.3 0.048 13.7 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_30 PF13556.6 AAZ33709.1 - 0.02 14.7 0.3 0.069 13.0 0.2 2.0 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain MLTR_LBD PF17765.1 AAZ33709.1 - 0.043 13.9 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 MmyB-like transcription regulator ligand binding domain HTH_50 PF18024.1 AAZ33709.1 - 0.072 12.7 0.0 0.22 11.2 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain PAS_8 PF13188.7 AAZ33709.1 - 0.073 13.1 0.0 0.31 11.1 0.0 2.1 1 0 0 1 1 1 0 PAS domain HTH_17 PF12728.7 AAZ33709.1 - 0.095 12.9 0.1 0.93 9.7 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_29 PF13551.6 AAZ33709.1 - 0.11 12.6 0.0 0.31 11.1 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn helix Sigma70_ECF PF07638.11 AAZ33709.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 ECF sigma factor HTH_22 PF13309.6 AAZ33709.1 - 0.14 12.3 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 HTH domain AAA_30 PF13604.6 AAZ33709.1 - 0.21 11.3 1.2 0.36 10.5 0.1 1.9 2 1 1 3 3 3 0 AAA domain DDE_Tnp_1 PF01609.21 AAZ33710.1 - 3.1e-36 125.1 1.3 5.4e-36 124.2 0.9 1.5 2 0 0 2 2 2 1 Transposase DDE domain DUF772 PF05598.11 AAZ33710.1 - 1.7e-19 69.6 0.0 3.6e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 Transposase domain (DUF772) DDE_Tnp_1_6 PF13751.6 AAZ33710.1 - 2.7e-06 27.6 0.9 5.3e-06 26.7 0.9 1.5 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 AAZ33710.1 - 1e-05 25.6 0.1 1.6e-05 25.0 0.1 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 AAZ33710.1 - 0.00028 20.6 1.1 0.00047 19.9 1.1 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease FecR PF04773.13 AAZ33711.1 - 4.2e-18 65.8 0.1 6.8e-18 65.1 0.1 1.4 1 0 0 1 1 1 1 FecR protein DUF4880 PF16220.5 AAZ33711.1 - 3e-07 30.2 3.9 3e-07 30.2 3.9 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4880) DUF4974 PF16344.5 AAZ33711.1 - 0.25 11.4 0.0 0.47 10.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4974) MR_MLE_C PF13378.6 AAZ33712.1 - 1.3e-62 211.2 0.0 1.7e-62 210.9 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 AAZ33712.1 - 4e-27 94.7 0.0 7.2e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Glyoxalase_4 PF13669.6 AAZ33713.1 - 2.5e-07 30.9 0.0 3.3e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 AAZ33713.1 - 9.2e-06 25.9 0.5 1.3e-05 25.4 0.5 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 AAZ33713.1 - 0.011 16.5 0.0 0.016 16.0 0.0 1.3 1 1 0 1 1 1 0 Glyoxalase-like domain Glyoxalase_2 PF12681.7 AAZ33713.1 - 0.016 15.1 0.1 0.13 12.2 0.1 2.1 1 1 0 1 1 1 0 Glyoxalase-like domain SBP_bac_3 PF00497.20 AAZ33714.1 - 5e-32 111.1 0.0 8.9e-32 110.3 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 SLT PF01464.20 AAZ33714.1 - 1.5e-21 76.2 0.1 2.7e-21 75.4 0.1 1.4 1 0 0 1 1 1 1 Transglycosylase SLT domain Lysozyme_like PF13702.6 AAZ33714.1 - 0.0053 16.5 0.0 0.011 15.5 0.0 1.5 1 1 0 1 1 1 1 Lysozyme-like NMT1 PF09084.11 AAZ33714.1 - 0.032 14.2 0.0 0.056 13.4 0.0 1.3 1 0 0 1 1 1 0 NMT1/THI5 like MCPsignal PF00015.21 AAZ33715.1 - 1.9e-43 148.2 32.8 7.1e-43 146.4 20.0 3.2 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain 4HB_MCP_1 PF12729.7 AAZ33715.1 - 1.9e-22 79.7 6.1 1.9e-22 79.7 6.1 3.6 4 1 1 5 5 5 1 Four helix bundle sensory module for signal transduction HAMP PF00672.25 AAZ33715.1 - 5.4e-11 42.7 16.9 5.7e-09 36.2 0.4 5.1 5 0 0 5 5 5 2 HAMP domain TarH PF02203.15 AAZ33715.1 - 2.3e-07 30.9 5.2 2.3e-07 30.9 5.2 3.8 3 2 0 4 4 4 1 Tar ligand binding domain homologue Nab2 PF11517.8 AAZ33715.1 - 0.058 13.7 1.5 1.1 9.6 0.0 3.3 4 0 0 4 4 4 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Renin_r PF07850.14 AAZ33715.1 - 0.079 13.6 0.2 0.55 10.9 0.2 2.5 1 0 0 1 1 1 0 Renin receptor-like protein AcetDehyd-dimer PF09290.11 AAZ33715.1 - 1.7 8.9 12.3 1.8 8.7 1.7 2.5 2 0 0 2 2 2 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation IFT57 PF10498.9 AAZ33715.1 - 2.2 7.2 17.8 0.13 11.2 0.6 3.3 3 0 0 3 3 3 0 Intra-flagellar transport protein 57 Dmrt1 PF12374.8 AAZ33715.1 - 2.2 8.8 6.3 24 5.5 0.3 2.9 2 1 0 2 2 2 0 Double-sex mab3 related transcription factor 1 DASH_Dad3 PF08656.10 AAZ33715.1 - 4.2 7.5 8.0 1.6 8.9 1.5 3.5 3 0 0 3 3 3 0 DASH complex subunit Dad3 LysR_substrate PF03466.20 AAZ33716.1 - 7.1e-30 103.9 2.1 1e-29 103.4 2.1 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ33716.1 - 1.9e-18 66.1 1.2 4.3e-18 65.0 1.2 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family Ogr_Delta PF04606.12 AAZ33716.1 - 0.18 11.8 0.1 0.39 10.7 0.1 1.5 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger Penicil_amidase PF01804.18 AAZ33717.1 - 2.5e-181 605.1 5.1 2.8e-181 604.9 5.1 1.0 1 0 0 1 1 1 1 Penicillin amidase AAA PF00004.29 AAZ33718.1 - 1.3e-28 100.0 0.0 2.8e-28 99.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 AAZ33718.1 - 9.7e-05 22.6 0.0 0.00018 21.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 AAZ33718.1 - 0.00012 22.1 0.0 0.0007 19.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 AAZ33718.1 - 0.0014 18.4 0.0 0.0035 17.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 AAZ33718.1 - 0.0015 18.8 1.1 0.051 13.9 0.2 2.8 2 1 0 2 2 2 1 AAA domain IPT PF01745.16 AAZ33718.1 - 0.0098 15.3 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 1 Isopentenyl transferase DUF853 PF05872.12 AAZ33718.1 - 0.02 13.5 0.0 0.034 12.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) NDUFV3 PF15880.5 AAZ33718.1 - 0.021 14.9 0.8 0.039 14.0 0.8 1.4 1 0 0 1 1 1 0 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial AAA_33 PF13671.6 AAZ33718.1 - 0.022 14.9 0.0 0.064 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain HTH_23 PF13384.6 AAZ33718.1 - 0.033 14.0 0.8 0.16 11.8 0.1 2.5 3 0 0 3 3 3 0 Homeodomain-like domain HTH_11 PF08279.12 AAZ33718.1 - 0.04 13.9 1.0 0.12 12.3 0.1 2.3 3 0 0 3 3 3 0 HTH domain Mg_chelatase PF01078.21 AAZ33718.1 - 0.057 12.8 0.0 1.3 8.4 0.0 2.4 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 AAZ33718.1 - 0.089 12.7 0.3 0.33 10.8 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 AAZ33718.1 - 0.1 12.8 0.0 0.22 11.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 AAZ33718.1 - 0.13 12.6 2.2 5.3 7.4 0.1 2.8 2 1 0 3 3 3 0 AAA ATPase domain 7TMR-DISM_7TM PF07695.11 AAZ33719.1 - 9.8e-53 179.1 29.8 1.4e-52 178.6 29.8 1.2 1 0 0 1 1 1 1 7TM diverse intracellular signalling 7TMR-DISMED2 PF07696.11 AAZ33719.1 - 2.3e-37 128.0 0.1 6e-37 126.7 0.1 1.8 2 0 0 2 2 2 1 7TMR-DISM extracellular 2 HATPase_c PF02518.26 AAZ33719.1 - 5.1e-25 88.2 0.0 7.8e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAZ33719.1 - 2.7e-12 46.6 0.2 2.7e-12 46.6 0.2 1.9 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain SLATT_fungal PF18142.1 AAZ33719.1 - 4.9 7.2 5.0 12 5.9 5.0 1.6 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain RIO1 PF01163.22 AAZ33720.1 - 2.1e-45 154.6 0.0 2.9e-45 154.2 0.0 1.1 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 AAZ33720.1 - 5.3e-05 23.3 7.9 0.11 12.4 0.0 3.7 2 1 2 4 4 4 2 Phosphotransferase enzyme family Kdo PF06293.14 AAZ33720.1 - 0.028 13.8 0.2 0.23 10.8 0.2 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family UDPG_MGDP_dh_N PF03721.14 AAZ33721.1 - 2.6e-64 216.2 0.2 1.1e-63 214.2 0.0 2.0 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 AAZ33721.1 - 1e-29 102.6 0.0 1.9e-29 101.7 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 AAZ33721.1 - 9.6e-14 51.7 0.0 5.8e-13 49.2 0.0 2.3 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain ApbA PF02558.16 AAZ33721.1 - 0.0043 16.7 0.0 0.0078 15.9 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 AAZ33721.1 - 0.039 14.1 0.0 0.19 11.9 0.0 2.2 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 AAZ33721.1 - 0.067 13.4 0.1 0.36 11.1 0.1 2.1 1 1 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_Gly3P_dh_N PF01210.23 AAZ33721.1 - 0.11 12.5 0.0 6.1 6.8 0.0 2.5 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 AAZ33721.1 - 0.15 11.9 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 AAZ33721.1 - 0.19 11.1 0.1 0.73 9.2 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SbcCD_C PF13558.6 AAZ33722.1 - 0.1 12.8 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Sacchrp_dh_NADP PF03435.18 AAZ33723.1 - 6.5e-10 39.4 0.0 1.1e-09 38.6 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 AAZ33723.1 - 0.00086 19.3 0.1 0.0031 17.4 0.0 1.9 2 0 0 2 2 2 1 KR domain Radical_SAM PF04055.21 AAZ33724.1 - 6.2e-06 26.7 0.0 1.2e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily HHH_3 PF12836.7 AAZ33724.1 - 2.2e-05 24.6 0.1 9.4e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 AAZ33724.1 - 0.011 16.3 0.0 0.026 15.1 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain PDH PF02153.17 AAZ33725.1 - 1.4e-32 112.7 0.0 3.2e-32 111.6 0.0 1.6 2 0 0 2 2 2 1 Prephenate dehydrogenase EPSP_synthase PF00275.20 AAZ33725.1 - 9.5e-27 93.7 0.0 1.2e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) UPF0270 PF06794.12 AAZ33727.1 - 5.4e-27 93.7 0.0 6e-27 93.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0270) cNMP_binding PF00027.29 AAZ33728.1 - 1.7e-23 82.5 0.6 2.5e-23 81.9 0.1 1.5 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain FliMN_C PF01052.20 AAZ33729.1 - 3.9e-24 84.4 1.5 5.8e-24 83.9 1.5 1.3 1 0 0 1 1 1 1 Type III flagellar switch regulator (C-ring) FliN C-term DUF5064 PF16703.5 AAZ33730.1 - 2.7e-50 169.7 0.3 3e-50 169.6 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5064) LysR_substrate PF03466.20 AAZ33731.1 - 2.8e-30 105.2 5.4 4.1e-30 104.7 5.4 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ33731.1 - 2.4e-21 75.4 0.3 6.6e-21 74.0 0.3 1.8 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family Glyco_tranf_2_3 PF13641.6 AAZ33732.1 - 0.0027 17.6 0.0 0.0038 17.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 PhoD PF09423.10 AAZ33733.1 - 7.2e-09 35.1 0.0 1e-06 28.0 0.0 3.0 2 1 0 2 2 2 1 PhoD-like phosphatase Mannitol_dh_C PF08125.13 AAZ33734.1 - 1e-77 261.0 0.0 1.5e-77 260.5 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain FGGY_N PF00370.21 AAZ33734.1 - 3.2e-74 249.6 0.0 5.4e-74 248.8 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Mannitol_dh PF01232.23 AAZ33734.1 - 1.4e-49 168.1 0.0 4.3e-49 166.6 0.0 1.9 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain FGGY_C PF02782.16 AAZ33734.1 - 2.2e-26 92.8 0.4 3.9e-26 92.0 0.4 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 AAZ33734.1 - 0.046 13.2 0.2 0.11 12.0 0.0 1.6 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Pentapeptide PF00805.22 AAZ33734.1 - 0.15 11.8 1.1 2.4 7.9 0.1 2.6 2 0 0 2 2 2 0 Pentapeptide repeats (8 copies) Dala_Dala_lig_C PF07478.13 AAZ33735.1 - 1.1e-70 237.3 0.0 1.4e-70 237.0 0.0 1.1 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Dala_Dala_lig_N PF01820.21 AAZ33735.1 - 2.8e-28 98.4 0.0 4.3e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase N-terminus ATP-grasp PF02222.22 AAZ33735.1 - 7.3e-12 45.2 0.0 1.2e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 AAZ33735.1 - 2.8e-06 27.0 0.0 4.5e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 AAZ33735.1 - 7.3e-05 22.9 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 AAZ33735.1 - 0.0022 17.3 0.0 1.5 8.0 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_4 PF13535.6 AAZ33735.1 - 0.0031 17.1 0.2 0.025 14.2 0.2 2.2 1 1 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 AAZ33735.1 - 0.0048 16.5 0.0 0.011 15.3 0.0 1.7 1 1 0 1 1 1 1 RimK-like ATP-grasp domain MCPsignal PF00015.21 AAZ33736.1 - 3.2e-48 163.8 34.2 7.6e-48 162.6 19.5 2.3 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain PAS_3 PF08447.12 AAZ33736.1 - 1.5e-17 63.6 0.0 3.6e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AAZ33736.1 - 8e-11 42.1 0.0 2.6e-10 40.5 0.0 1.9 2 0 0 2 2 1 1 PAS domain PAS PF00989.25 AAZ33736.1 - 1.7e-09 37.7 0.0 6.1e-09 35.9 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AAZ33736.1 - 6.3e-06 26.4 0.2 5.1e-05 23.5 0.0 2.5 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 AAZ33736.1 - 0.00019 21.3 0.0 0.00071 19.5 0.0 2.0 1 0 0 1 1 1 1 PAS domain KELK PF15796.5 AAZ33736.1 - 0.0097 16.3 1.4 0.018 15.5 0.5 2.0 2 0 0 2 2 1 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase DASH_Duo1 PF08651.10 AAZ33736.1 - 0.15 11.9 1.2 1.7 8.5 0.2 3.3 3 0 0 3 3 3 0 DASH complex subunit Duo1 ABC_membrane PF00664.23 AAZ33736.1 - 0.5 10.0 2.1 16 5.0 0.1 2.4 2 0 0 2 2 2 0 ABC transporter transmembrane region DUF948 PF06103.11 AAZ33736.1 - 0.68 10.2 21.5 4.5 7.6 0.2 4.4 1 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DASH_Dad3 PF08656.10 AAZ33736.1 - 0.69 10.0 3.1 2.4 8.3 2.3 2.5 2 1 0 2 2 1 0 DASH complex subunit Dad3 ISG65-75 PF11727.8 AAZ33736.1 - 0.77 8.9 13.1 1.9 7.6 2.4 2.1 2 0 0 2 2 2 0 Invariant surface glycoprotein Syntaxin_2 PF14523.6 AAZ33736.1 - 1.3 9.4 10.8 1.7 9.0 0.2 3.6 2 1 0 3 3 3 0 Syntaxin-like protein YkyA PF10368.9 AAZ33736.1 - 1.8 8.2 5.8 12 5.6 0.3 2.4 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein CorA PF01544.18 AAZ33736.1 - 1.8 7.8 9.2 0.27 10.5 1.9 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein CENP-F_leu_zip PF10473.9 AAZ33736.1 - 2.4 8.2 8.6 0.93 9.5 1.9 2.4 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ERM PF00769.19 AAZ33736.1 - 4.2 7.1 18.9 6.3 6.5 3.9 2.3 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Corazonin PF17308.2 AAZ33736.1 - 4.4 7.7 6.3 0.94 9.9 1.7 2.1 2 0 0 2 2 2 0 Pro-corazonin ZapB PF06005.12 AAZ33736.1 - 4.8 7.7 13.8 5.8 7.4 0.2 4.0 3 1 0 3 3 3 0 Cell division protein ZapB Spc7 PF08317.11 AAZ33736.1 - 5.2 5.9 12.5 1.2 8.0 3.3 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4200 PF13863.6 AAZ33736.1 - 6.3 7.2 9.2 5.3 7.5 1.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) RF-1 PF00472.20 AAZ33737.1 - 7.1e-24 84.0 0.3 9.1e-24 83.6 0.3 1.1 1 0 0 1 1 1 1 RF-1 domain MRP-S28 PF10213.9 AAZ33737.1 - 0.0065 16.9 0.0 0.0079 16.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein DUF4350 PF14258.6 AAZ33737.1 - 0.038 14.4 0.1 2.4 8.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) Pro_CA PF00484.19 AAZ33738.1 - 3.9e-51 173.4 0.3 4.7e-51 173.2 0.3 1.1 1 0 0 1 1 1 1 Carbonic anhydrase HTH_6 PF01418.17 AAZ33739.1 - 3e-13 49.6 0.1 5.6e-13 48.7 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain, rpiR family SIS PF01380.22 AAZ33739.1 - 2.3e-12 46.9 0.0 3.1e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 SIS domain SIS_2 PF13580.6 AAZ33739.1 - 4e-07 30.1 0.1 0.0017 18.3 0.0 2.4 1 1 1 2 2 2 2 SIS domain LacI PF00356.21 AAZ33739.1 - 0.0071 16.1 0.2 0.023 14.5 0.2 1.9 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family TetR_N PF00440.23 AAZ33739.1 - 0.019 14.7 0.2 0.066 13.0 0.2 1.9 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family HTH_31 PF13560.6 AAZ33739.1 - 0.034 14.5 1.2 0.1 13.0 1.2 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain MarR PF01047.22 AAZ33739.1 - 0.074 13.0 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 MarR family HRDC PF00570.23 AAZ33739.1 - 0.12 12.4 0.0 31 4.6 0.0 3.1 3 0 0 3 3 3 0 HRDC domain LysR_substrate PF03466.20 AAZ33740.1 - 1.1e-44 152.3 2.6 1.7e-44 151.7 2.6 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ33740.1 - 1.7e-16 59.9 0.5 3.4e-16 58.9 0.5 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family PBP_like PF12727.7 AAZ33740.1 - 0.00039 19.6 0.0 0.00053 19.2 0.0 1.2 1 0 0 1 1 1 1 PBP superfamily domain PALP PF00291.25 AAZ33741.1 - 2.6e-84 283.1 2.9 3.3e-84 282.8 2.9 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 AAZ33741.1 - 8.5e-47 156.9 0.0 6e-26 90.0 0.0 2.4 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase DUF3335 PF11814.8 AAZ33741.1 - 0.11 11.9 0.1 0.21 11.0 0.1 1.4 1 0 0 1 1 1 0 Peptidase_C39 like family TMP_2 PF06791.13 AAZ33741.1 - 0.18 11.5 2.5 0.53 9.9 0.9 2.2 2 0 0 2 2 2 0 Prophage tail length tape measure protein NTP_transferase PF00483.23 AAZ33742.1 - 1.1e-07 31.7 0.0 1.4e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase RBDV_coat PF06593.11 AAZ33742.1 - 0.11 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Raspberry bushy dwarf virus coat protein Aminotran_1_2 PF00155.21 AAZ33743.1 - 2.1e-47 162.0 0.0 2.4e-47 161.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 AAZ33743.1 - 1.6e-06 27.7 0.0 2.3e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 AAZ33743.1 - 0.0016 17.5 0.0 0.0023 17.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Costars PF14705.6 AAZ33743.1 - 0.12 12.5 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 Costars RNAse_A_bac PF18431.1 AAZ33744.1 - 3.9e-23 82.6 0.0 7.1e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial CdiA-CT RNAse A domain GTP_cyclohydro2 PF00925.20 AAZ33745.1 - 6e-67 224.3 0.0 7.4e-67 224.0 0.0 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase II Glyco_hydro_3_C PF01915.22 AAZ33746.1 - 2.4e-48 164.8 0.0 2.4e-47 161.5 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 AAZ33746.1 - 6.9e-42 143.9 0.0 1.4e-41 143.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain PA14 PF07691.12 AAZ33746.1 - 1.8e-30 105.6 0.0 3.8e-30 104.6 0.0 1.6 1 0 0 1 1 1 1 PA14 domain Fn3-like PF14310.6 AAZ33746.1 - 2.1e-26 91.8 0.1 2.2e-25 88.6 0.1 2.7 2 0 0 2 2 2 1 Fibronectin type III-like domain YscO PF07321.12 AAZ33747.1 - 0.0066 16.4 33.5 0.0086 16.0 33.5 1.1 1 0 0 1 1 1 1 Type III secretion protein YscO DIT1_PvcA PF05141.12 AAZ33747.1 - 0.07 12.6 4.8 0.081 12.4 4.8 1.1 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein DUF3713 PF12506.8 AAZ33747.1 - 0.089 13.1 0.4 0.15 12.3 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3713) PIN_4 PF13638.6 AAZ33747.1 - 0.19 12.0 7.4 0.49 10.7 7.4 1.8 1 1 0 1 1 1 0 PIN domain rve PF00665.26 AAZ33748.1 - 3.7e-34 117.5 0.1 5.8e-34 116.8 0.1 1.3 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 AAZ33748.1 - 5.5e-12 46.1 0.0 7.7e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 DDE domain rve_3 PF13683.6 AAZ33748.1 - 7.3e-11 41.7 0.8 7.3e-11 41.7 0.8 1.8 2 0 0 2 2 2 1 Integrase core domain HTH_21 PF13276.6 AAZ33748.1 - 5.2e-10 39.3 1.4 1.3e-09 38.0 0.1 2.2 2 0 0 2 2 2 1 HTH-like domain rve_2 PF13333.6 AAZ33748.1 - 0.0017 18.5 0.0 0.0033 17.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Sod_Fe_C PF02777.18 AAZ33749.1 - 4.8e-38 129.4 0.0 1.7e-37 127.7 0.0 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 AAZ33749.1 - 2.2e-33 114.6 0.8 3.4e-33 113.9 0.8 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Transgly PF00912.22 AAZ33750.1 - 3.7e-28 98.2 0.0 1e-27 96.7 0.0 1.7 2 0 0 2 2 2 1 Transglycosylase Transpeptidase PF00905.22 AAZ33750.1 - 7.2e-08 32.0 0.0 5.1e-06 25.9 0.0 2.2 2 0 0 2 2 2 2 Penicillin binding protein transpeptidase domain Bac_export_2 PF01312.19 AAZ33751.1 - 1.3e-17 64.0 0.5 1.5e-17 63.9 0.5 1.0 1 0 0 1 1 1 1 FlhB HrpN YscU SpaS Family Phosphonate-bd PF12974.7 AAZ33752.1 - 7.7e-70 235.2 0.2 9.9e-70 234.9 0.2 1.1 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein OpuAC PF04069.12 AAZ33752.1 - 0.0024 17.5 0.2 0.014 15.0 0.1 2.1 1 1 1 2 2 2 1 Substrate binding domain of ABC-type glycine betaine transport system SBP_bac_11 PF13531.6 AAZ33752.1 - 0.0083 15.9 0.2 0.015 15.1 0.2 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein OmpA PF00691.20 AAZ33753.1 - 9.4e-14 51.6 0.0 2.1e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 OmpA family FancD2 PF14631.6 AAZ33753.1 - 1.7 5.9 2.6 2.1 5.6 2.6 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease SNARE_assoc PF09335.11 AAZ33754.1 - 1.2e-16 61.3 5.8 7.8e-16 58.7 2.4 2.2 1 1 1 2 2 2 2 SNARE associated Golgi protein Pyr_redox_2 PF07992.14 AAZ33755.1 - 5.8e-66 222.7 0.0 7.9e-66 222.3 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 AAZ33755.1 - 5.9e-37 126.3 0.1 1.1e-36 125.4 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 AAZ33755.1 - 1.8e-20 73.3 4.9 4.5e-18 65.6 0.1 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAZ33755.1 - 9.8e-18 64.4 0.0 5e-16 58.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 AAZ33755.1 - 3.7e-06 26.4 0.9 0.015 14.6 1.1 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 AAZ33755.1 - 1.1e-05 24.7 0.0 0.0005 19.3 0.0 2.2 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 AAZ33755.1 - 1.3e-05 24.1 1.4 0.099 11.3 0.0 3.3 2 1 0 3 3 3 2 HI0933-like protein GIDA PF01134.22 AAZ33755.1 - 0.00011 21.5 2.9 0.002 17.3 1.8 2.5 2 1 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 AAZ33755.1 - 0.00039 19.9 1.6 0.00047 19.6 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 AAZ33755.1 - 0.0014 18.0 0.7 1.3 8.4 0.4 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 AAZ33755.1 - 0.0041 17.5 0.0 0.48 10.9 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding XdhC_C PF13478.6 AAZ33755.1 - 0.0091 16.5 0.1 3 8.4 0.0 2.4 2 0 0 2 2 2 1 XdhC Rossmann domain FAD_binding_2 PF00890.24 AAZ33755.1 - 0.0096 15.0 2.7 0.11 11.6 2.3 2.4 2 0 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.18 AAZ33755.1 - 0.016 15.1 0.5 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 AAZ33755.1 - 0.044 12.8 0.1 0.36 9.8 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 AAZ33755.1 - 0.073 12.3 0.4 0.16 11.2 0.4 1.5 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.6 AAZ33755.1 - 0.4 10.9 7.7 0.12 12.6 1.5 2.8 3 0 0 3 3 2 0 NAD(P)-binding Rossmann-like domain Response_reg PF00072.24 AAZ33756.1 - 2.7e-25 88.7 0.0 4.3e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAZ33756.1 - 7.6e-24 83.6 0.1 2e-23 82.3 0.0 1.7 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal TBD PF12845.7 AAZ33756.1 - 0.015 15.2 0.0 0.11 12.4 0.0 2.2 2 0 0 2 2 2 0 TBD domain dCMP_cyt_deam_1 PF00383.23 AAZ33757.1 - 2.8e-23 81.7 0.0 3.6e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 AAZ33757.1 - 2.3e-22 79.2 0.0 2.8e-22 79.0 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC4_like PF18774.1 AAZ33757.1 - 0.00017 21.5 0.0 0.0025 17.7 0.0 2.0 1 1 0 1 1 1 1 APOBEC4-like -AID/APOBEC-deaminase APOBEC2 PF18772.1 AAZ33757.1 - 0.00027 21.0 0.0 0.016 15.3 0.0 2.0 1 1 0 1 1 1 1 APOBEC2 SNAD4 PF18750.1 AAZ33757.1 - 0.00031 20.8 0.0 0.0061 16.7 0.0 2.0 2 0 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 AAZ33757.1 - 0.00035 20.7 0.0 0.51 10.4 0.0 2.1 2 0 0 2 2 2 2 Novel AID APOBEC clade 1 Bd3614-deam PF14439.6 AAZ33757.1 - 0.00041 20.4 0.0 0.00054 20.0 0.0 1.2 1 0 0 1 1 1 1 Bd3614-like deaminase APOBEC_N PF08210.11 AAZ33757.1 - 0.013 15.4 0.0 2.3 8.1 0.0 2.0 1 1 1 2 2 2 0 APOBEC-like N-terminal domain APOBEC4 PF18775.1 AAZ33757.1 - 0.03 14.5 0.0 4.2 7.6 0.0 2.2 2 0 0 2 2 2 0 APOBEC4 XOO_2897-deam PF14440.6 AAZ33757.1 - 0.074 13.2 0.0 0.13 12.4 0.0 1.5 1 1 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase NAD2 PF18782.1 AAZ33757.1 - 0.18 11.9 0.0 6.6 6.8 0.0 2.0 2 0 0 2 2 2 0 Novel AID APOBEC clade 2 Rotamase PF00639.21 AAZ33758.1 - 1.4e-48 163.8 0.0 4.2e-27 95.0 0.0 3.3 2 1 1 3 3 3 2 PPIC-type PPIASE domain Rotamase_3 PF13616.6 AAZ33758.1 - 1.9e-48 163.8 0.0 2.1e-30 105.6 0.0 2.4 2 0 0 2 2 2 2 PPIC-type PPIASE domain SurA_N PF09312.11 AAZ33758.1 - 7.3e-45 151.9 6.0 2e-44 150.4 6.0 1.8 1 0 0 1 1 1 1 SurA N-terminal domain Rotamase_2 PF13145.6 AAZ33758.1 - 4.3e-21 76.0 0.0 4.9e-10 40.3 0.0 2.6 1 1 1 2 2 2 2 PPIC-type PPIASE domain SurA_N_3 PF13624.6 AAZ33758.1 - 1.1e-15 57.8 2.6 1.1e-15 57.8 2.6 2.3 1 1 1 2 2 2 1 SurA N-terminal domain SurA_N_2 PF13623.6 AAZ33758.1 - 5e-09 36.2 8.9 1.2e-08 34.9 1.6 2.5 1 1 1 2 2 2 1 SurA N-terminal domain Trigger_C PF05698.14 AAZ33758.1 - 0.00038 20.5 1.4 0.00038 20.5 1.4 3.0 2 1 1 3 3 3 1 Bacterial trigger factor protein (TF) C-terminus KORA PF16509.5 AAZ33758.1 - 0.066 13.5 0.3 1 9.7 0.2 2.5 2 0 0 2 2 2 0 TrfB plasmid transcriptional repressor SpoVIF PF14069.6 AAZ33758.1 - 5.3 6.9 6.0 0.86 9.4 0.0 2.6 4 0 0 4 4 4 0 Stage VI sporulation protein F UPF0126 PF03458.13 AAZ33759.1 - 3.6e-44 148.5 18.6 4.4e-22 77.8 5.2 2.3 2 0 0 2 2 2 2 UPF0126 domain ICMT PF04140.14 AAZ33759.1 - 0.047 14.1 0.2 0.12 12.8 0.2 1.8 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family SpoIIIAC PF06686.11 AAZ33759.1 - 0.32 11.2 8.9 0.34 11.1 0.2 3.6 3 1 0 3 3 3 0 Stage III sporulation protein AC/AD protein family Haem_oxygenas_2 PF14518.6 AAZ33760.1 - 6.4e-33 114.0 0.1 1.1e-32 113.2 0.1 1.4 1 0 0 1 1 1 1 Iron-containing redox enzyme HTH_IclR PF09339.10 AAZ33761.1 - 9.4e-14 50.9 0.6 3.1e-13 49.3 0.2 2.0 2 0 0 2 2 2 1 IclR helix-turn-helix domain IclR PF01614.18 AAZ33761.1 - 3.8e-10 39.7 0.0 6.3e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_24 PF13412.6 AAZ33761.1 - 6.6e-06 25.6 0.0 2e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 AAZ33761.1 - 5.4e-05 23.0 0.1 0.00011 22.0 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family TrmB PF01978.19 AAZ33761.1 - 0.00033 20.5 0.0 0.0012 18.7 0.0 1.8 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 AAZ33761.1 - 0.0014 18.5 0.1 0.035 14.0 0.0 2.3 2 0 0 2 2 2 1 MarR family DUF4423 PF14394.6 AAZ33761.1 - 0.042 13.6 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) HTH_11 PF08279.12 AAZ33761.1 - 0.073 13.0 0.1 0.53 10.3 0.0 2.4 3 0 0 3 3 3 0 HTH domain Sigma70_r3 PF04539.16 AAZ33761.1 - 0.13 12.4 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-70 region 3 HTH_6 PF01418.17 AAZ33761.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family HTH_20 PF12840.7 AAZ33761.1 - 0.13 12.3 0.4 0.59 10.2 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.6 AAZ33761.1 - 0.15 11.9 0.0 2.3 8.1 0.0 2.3 2 0 0 2 2 2 0 Homeodomain-like domain Biotin_lipoyl_2 PF13533.6 AAZ33762.1 - 1.4e-19 69.6 8.8 2.9e-17 62.2 1.2 3.2 3 0 0 3 3 3 2 Biotin-lipoyl like HlyD_D23 PF16576.5 AAZ33762.1 - 4.5e-16 58.7 0.3 7.4e-16 58.0 0.3 1.3 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AAZ33762.1 - 3.2e-14 53.5 0.0 6.6e-08 33.2 0.0 2.5 2 1 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl PF00364.22 AAZ33762.1 - 0.0013 18.5 0.1 0.066 13.1 0.1 2.4 2 0 0 2 2 2 1 Biotin-requiring enzyme HlyD PF00529.20 AAZ33762.1 - 0.0031 17.4 0.0 0.02 14.8 0.0 2.0 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS PTS_EIIA_1 PF00358.20 AAZ33762.1 - 0.17 11.6 0.0 0.61 9.8 0.0 1.8 2 0 0 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 SCO1-SenC PF02630.14 AAZ33763.1 - 2.8e-39 134.1 0.0 3.7e-39 133.7 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 AAZ33763.1 - 1.7e-07 31.2 0.0 2.4e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 AAZ33763.1 - 0.00015 22.1 0.0 0.00024 21.4 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 AAZ33763.1 - 0.0016 18.1 0.0 0.0024 17.6 0.0 1.2 1 0 0 1 1 1 1 Redoxin BPD_transp_2 PF02653.16 AAZ33764.1 - 9.7e-50 169.2 37.4 1.1e-49 169.0 37.4 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component E1-E2_ATPase PF00122.20 AAZ33764.1 - 7.8 6.0 8.6 0.13 11.8 0.5 2.2 2 1 0 2 2 2 0 E1-E2 ATPase TonB_dep_Rec PF00593.24 AAZ33766.1 - 7.4e-44 151.4 46.2 7.4e-44 151.4 46.2 2.0 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 AAZ33766.1 - 3.8e-11 43.5 1.1 1.4e-10 41.7 1.1 2.0 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain OEP PF02321.18 AAZ33767.1 - 3.4e-48 164.0 26.5 1.3e-27 96.9 9.2 2.0 2 0 0 2 2 2 2 Outer membrane efflux protein Crr6 PF08847.11 AAZ33767.1 - 0.097 12.3 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Chlororespiratory reduction 6 Sugar_tr PF00083.24 AAZ33768.1 - 4.4e-32 111.5 27.4 9.9e-24 84.0 9.9 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 AAZ33768.1 - 6.9e-26 91.0 46.0 2.2e-18 66.3 26.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily HTH_Tnp_1 PF01527.20 AAZ33769.1 - 5.6e-18 65.0 1.4 7.9e-18 64.6 1.4 1.2 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.6 AAZ33769.1 - 0.00015 21.7 0.2 0.00031 20.7 0.0 1.6 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 AAZ33769.1 - 0.0003 20.8 0.1 0.00058 19.9 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AAZ33769.1 - 0.00035 20.3 1.4 0.0011 18.7 0.1 2.2 2 1 0 2 2 2 1 Homeodomain-like domain KASH_CCD PF14662.6 AAZ33769.1 - 0.006 16.4 3.0 0.0068 16.3 3.0 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH TSC22 PF01166.18 AAZ33769.1 - 0.0078 16.5 2.3 0.01 16.1 1.0 1.7 2 0 0 2 2 2 1 TSC-22/dip/bun family FlxA PF14282.6 AAZ33769.1 - 0.019 14.9 1.6 0.029 14.4 1.6 1.3 1 0 0 1 1 1 0 FlxA-like protein DivIC PF04977.15 AAZ33769.1 - 0.036 13.8 4.3 0.062 13.1 4.3 1.4 1 1 0 1 1 1 0 Septum formation initiator Shugoshin_N PF07558.11 AAZ33769.1 - 0.041 13.8 0.6 0.072 13.0 0.6 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region BLOC1_2 PF10046.9 AAZ33769.1 - 0.045 14.1 0.4 0.066 13.5 0.4 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3287 PF11690.8 AAZ33769.1 - 0.046 13.4 2.1 0.24 11.1 0.6 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF3287) M PF02370.16 AAZ33769.1 - 0.057 14.0 0.8 0.23 12.1 0.3 2.2 1 1 1 2 2 2 0 M protein repeat DUF4140 PF13600.6 AAZ33769.1 - 0.097 13.1 3.3 0.21 12.0 3.3 1.7 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) ZapB PF06005.12 AAZ33769.1 - 0.42 11.1 7.6 3.5 8.1 4.2 2.2 1 1 2 3 3 3 0 Cell division protein ZapB ABC_tran_CTD PF16326.5 AAZ33769.1 - 0.54 10.5 7.5 0.12 12.6 4.3 1.7 2 0 0 2 2 2 0 ABC transporter C-terminal domain GntP_permease PF02447.16 AAZ33770.1 - 1.9e-127 425.6 50.9 6.9e-65 219.5 24.5 2.0 1 1 0 2 2 2 2 GntP family permease CitMHS PF03600.16 AAZ33770.1 - 5.6e-19 68.4 52.0 5.6e-19 68.4 52.0 1.7 1 1 0 1 1 1 1 Citrate transporter ABC_tran PF00005.27 AAZ33771.1 - 1.3e-27 96.9 0.0 2.1e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAZ33771.1 - 4.5e-10 39.8 0.0 0.0003 20.7 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AAZ33771.1 - 5.1e-06 27.0 0.1 9e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AAZ33771.1 - 2.7e-05 23.8 0.1 5.3e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AAZ33771.1 - 0.00036 20.8 0.2 0.0054 17.0 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AAZ33771.1 - 0.0016 18.6 0.0 0.0099 16.1 0.0 2.1 3 0 0 3 3 2 1 AAA domain SMC_N PF02463.19 AAZ33771.1 - 0.0023 17.4 0.0 0.051 13.0 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AAZ33771.1 - 0.0024 18.4 0.0 0.0036 17.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 AAZ33771.1 - 0.0049 16.9 0.1 0.0094 16.0 0.1 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 AAZ33771.1 - 0.0055 17.1 0.1 0.0082 16.6 0.1 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 AAZ33771.1 - 0.0064 16.4 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_27 PF13514.6 AAZ33771.1 - 0.013 15.1 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 AAZ33771.1 - 0.024 14.4 0.0 0.031 14.0 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 AAZ33771.1 - 0.029 14.1 0.1 0.091 12.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 AAZ33771.1 - 0.04 13.1 0.2 0.36 10.0 0.1 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.6 AAZ33771.1 - 0.054 13.1 0.1 0.83 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain MukB PF04310.12 AAZ33771.1 - 0.073 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 MukB N-terminal IstB_IS21 PF01695.17 AAZ33771.1 - 0.079 12.7 0.1 3.4 7.3 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein NACHT PF05729.12 AAZ33771.1 - 0.09 12.7 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 AAZ33771.1 - 0.093 12.7 0.1 0.2 11.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 AAZ33771.1 - 0.1 12.5 0.1 0.24 11.3 0.1 1.6 1 0 0 1 1 1 0 NTPase ABC_ATPase PF09818.9 AAZ33771.1 - 0.11 11.2 0.2 4.7 5.9 0.1 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class T2SSE PF00437.20 AAZ33771.1 - 0.12 11.4 0.1 0.17 10.9 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 AAZ33771.1 - 0.14 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region cobW PF02492.19 AAZ33771.1 - 0.21 11.2 0.2 0.21 11.2 0.2 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 AAZ33771.1 - 0.28 11.1 0.0 0.46 10.4 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea BPD_transp_1 PF00528.22 AAZ33772.1 - 1.3e-08 34.8 23.9 1.3e-08 34.8 23.9 2.5 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Rotamase_3 PF13616.6 AAZ33773.1 - 1.1e-23 84.0 0.0 1.4e-23 83.6 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 AAZ33773.1 - 1.2e-21 77.5 0.0 1.5e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 AAZ33773.1 - 1.2e-07 32.6 0.0 1.3e-07 32.4 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain DUF4096 PF13340.6 AAZ33774.1 - 5.8e-25 87.3 0.4 1.5e-24 86.0 0.4 1.8 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1 PF01609.21 AAZ33774.1 - 2.5e-14 53.4 0.0 4.5e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AAZ33774.1 - 3.3e-10 40.2 0.2 9.4e-10 38.7 0.2 1.9 1 0 0 1 1 1 1 Transposase DDE domain HTH_Tnp_Tc3_2 PF01498.18 AAZ33774.1 - 0.061 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Transposase Orn_Arg_deC_N PF02784.16 AAZ33775.1 - 3.8e-31 108.3 0.0 4.9e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 AAZ33775.1 - 1.6e-05 25.1 0.0 8.7e-05 22.7 0.0 2.1 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ala_racemase_N PF01168.20 AAZ33775.1 - 0.00039 20.1 0.0 0.00051 19.8 0.0 1.3 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain Amidohydro_1 PF01979.20 AAZ33776.1 - 1.3e-10 41.1 0.2 3.1e-10 39.9 0.2 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.14 AAZ33776.1 - 0.0024 17.7 0.1 0.0035 17.2 0.1 1.3 1 0 0 1 1 1 1 Amidohydrolase ComA PF02679.15 AAZ33776.1 - 0.019 14.5 0.0 0.026 14.0 0.0 1.1 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) SprT-like PF10263.9 AAZ33777.1 - 7.5e-18 64.4 0.1 9.6e-18 64.1 0.1 1.1 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 AAZ33777.1 - 1.3e-07 31.4 4.3 2.9e-07 30.3 4.3 1.6 1 0 0 1 1 1 1 SprT-like zinc ribbon domain SBP_bac_5 PF00496.22 AAZ33778.1 - 1.1e-100 337.3 3.6 1.4e-100 337.0 3.6 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle TMEM65 PF10507.9 AAZ33778.1 - 0.16 12.0 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 65 Transposase_mut PF00872.18 AAZ33779.1 - 1.5e-117 392.7 0.0 1.9e-117 392.3 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ33779.1 - 7.7e-05 23.0 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain DUF4844 PF16133.5 AAZ33779.1 - 0.23 12.0 0.0 0.55 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) LysE PF01810.18 AAZ33780.1 - 6.2e-17 61.7 10.9 8.3e-17 61.3 10.9 1.1 1 0 0 1 1 1 1 LysE type translocator DUF5313 PF17240.2 AAZ33780.1 - 0.11 12.9 0.4 0.11 12.9 0.4 2.2 2 1 1 3 3 3 0 Family of unknown function (DUF5313) VRR_NUC PF08774.11 AAZ33781.1 - 1e-35 122.1 0.0 3e-35 120.6 0.0 1.9 2 0 0 2 2 2 1 VRR-NUC domain FANC_SAP PF18081.1 AAZ33781.1 - 2.7e-12 46.6 5.3 4.7e-12 45.9 3.7 2.3 2 0 0 2 2 2 1 Fanconi anemia-associated nuclease SAP domain FANCI_S1-cap PF14674.6 AAZ33781.1 - 0.15 12.1 0.2 0.56 10.3 0.0 2.0 2 0 0 2 2 2 0 FANCI solenoid 1 cap DTW PF03942.15 AAZ33783.1 - 2.9e-42 144.6 0.0 3.6e-42 144.3 0.0 1.0 1 0 0 1 1 1 1 DTW domain HI0933_like PF03486.14 AAZ33784.1 - 8.7e-153 508.8 0.0 9.8e-153 508.7 0.0 1.0 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 AAZ33784.1 - 2.8e-12 46.4 1.3 5.6e-10 38.9 0.2 2.9 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.6 AAZ33784.1 - 2.8e-11 43.2 0.5 8.4e-06 25.2 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 AAZ33784.1 - 3.9e-11 42.7 0.5 3.4e-10 39.7 0.5 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AAZ33784.1 - 4.8e-11 42.8 0.1 2.4e-06 27.4 0.1 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 AAZ33784.1 - 1.1e-09 38.2 0.0 1.3e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 AAZ33784.1 - 1.3e-07 32.0 0.4 0.0023 18.4 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AAZ33784.1 - 9.7e-07 28.2 1.8 0.00015 21.0 1.1 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 AAZ33784.1 - 1.1e-06 28.7 0.8 3.3e-06 27.2 0.8 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 AAZ33784.1 - 1.4e-05 25.2 0.0 6.9e-05 22.9 0.0 2.2 2 1 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 AAZ33784.1 - 2.5e-05 23.7 0.6 0.0012 18.2 0.5 2.3 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 AAZ33784.1 - 8.1e-05 22.0 0.0 0.00014 21.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 AAZ33784.1 - 0.00016 20.9 0.2 0.0055 15.8 0.2 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 AAZ33784.1 - 0.0028 17.0 0.0 0.0052 16.1 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 AAZ33784.1 - 0.032 13.8 0.1 0.059 12.9 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Amino_oxidase PF01593.24 AAZ33784.1 - 0.046 13.0 0.1 0.37 10.0 0.0 2.4 1 1 0 2 2 2 0 Flavin containing amine oxidoreductase ApbA PF02558.16 AAZ33784.1 - 0.073 12.7 0.1 0.22 11.2 0.1 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 AAZ33784.1 - 0.19 11.6 0.2 0.39 10.6 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2OG-FeII_Oxy_3 PF13640.6 AAZ33785.1 - 5.7e-20 72.0 0.0 8.4e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 AAZ33785.1 - 1e-14 54.9 0.0 1.6e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SBP_bac_5 PF00496.22 AAZ33786.1 - 3e-74 250.3 0.1 4.3e-74 249.7 0.1 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle Hydrolase_4 PF12146.8 AAZ33787.1 - 1.8e-28 99.4 0.0 2.1e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AAZ33787.1 - 1.3e-11 44.7 0.7 1e-09 38.4 0.6 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAZ33787.1 - 5.7e-10 40.2 8.4 8.4e-10 39.6 8.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family MOSC PF03473.17 AAZ33788.1 - 5.1e-32 110.6 0.0 7.2e-32 110.2 0.0 1.2 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 AAZ33788.1 - 4.3e-27 94.4 0.0 6e-27 93.9 0.0 1.2 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain LprI PF07007.12 AAZ33789.1 - 5.1e-19 68.8 10.0 6.1e-19 68.6 10.0 1.1 1 0 0 1 1 1 1 Lysozyme inhibitor LprI DUF3077 PF11275.8 AAZ33790.1 - 4.5e-08 33.2 0.0 5.2e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3077) DUF2333 PF10095.9 AAZ33791.1 - 6.2e-154 511.9 0.1 7.6e-154 511.6 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2333) DUF347 PF03988.12 AAZ33791.1 - 0.011 15.9 0.2 0.022 14.9 0.2 1.5 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) DUF3311 PF11755.8 AAZ33791.1 - 0.2 11.6 2.2 0.4 10.7 2.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3311) OmpW PF03922.14 AAZ33792.1 - 2.2e-68 229.9 0.3 2.5e-68 229.8 0.3 1.0 1 0 0 1 1 1 1 OmpW family OMP_b-brl PF13505.6 AAZ33792.1 - 4e-14 53.1 1.4 5.3e-14 52.7 1.4 1.1 1 0 0 1 1 1 1 Outer membrane protein beta-barrel domain Opacity PF02462.15 AAZ33792.1 - 8e-06 26.0 0.2 3.5e-05 23.9 0.1 1.9 1 1 0 2 2 2 1 Opacity family porin protein DUF2715 PF10895.8 AAZ33792.1 - 0.0081 15.8 0.0 2.1 7.9 0.0 2.2 1 1 0 2 2 2 2 Domain of unknown function (DUF2715) Porin_2 PF02530.14 AAZ33792.1 - 0.05 12.9 0.1 0.076 12.3 0.1 1.3 1 0 0 1 1 1 0 Porin subfamily YadA_anchor PF03895.15 AAZ33792.1 - 2.2 8.5 4.9 12 6.1 0.1 3.9 4 1 1 5 5 5 0 YadA-like membrane anchor domain CheW PF01584.19 AAZ33793.1 - 1.7e-33 115.2 0.2 2.5e-33 114.6 0.2 1.3 1 0 0 1 1 1 1 CheW-like domain Response_reg PF00072.24 AAZ33793.1 - 2e-17 63.4 0.3 3.6e-17 62.6 0.3 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Sulfate_transp PF00916.20 AAZ33794.1 - 2.3e-83 280.1 21.3 3.2e-83 279.6 21.3 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 AAZ33794.1 - 4.4e-11 42.4 0.0 8.4e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 AAZ33794.1 - 4.9e-08 33.2 0.3 1.7e-07 31.5 0.1 2.0 2 0 0 2 2 2 1 STAS domain EthD PF07110.11 AAZ33795.1 - 5.7e-12 46.6 0.0 7.2e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 EthD domain OsmC PF02566.19 AAZ33796.1 - 1.8e-15 57.2 0.0 2.8e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 OsmC-like protein ABC_tran PF00005.27 AAZ33797.1 - 2.8e-35 121.8 0.0 4.8e-35 121.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter BCA_ABC_TP_C PF12399.8 AAZ33797.1 - 1e-10 41.3 0.1 1.7e-10 40.5 0.1 1.4 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_21 PF13304.6 AAZ33797.1 - 5.5e-07 29.7 0.1 0.004 17.0 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AAZ33797.1 - 0.0013 19.3 0.1 0.0023 18.5 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AAZ33797.1 - 0.003 17.3 0.1 0.016 14.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAZ33797.1 - 0.018 15.4 0.1 0.037 14.4 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 AAZ33797.1 - 0.022 14.5 0.2 0.073 12.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain SMC_N PF02463.19 AAZ33797.1 - 0.033 13.6 0.4 0.54 9.7 0.2 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AAZ33797.1 - 0.048 13.9 0.3 0.63 10.3 0.3 2.2 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 AAZ33797.1 - 0.078 12.9 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase Mg_chelatase PF01078.21 AAZ33797.1 - 0.082 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SRP54 PF00448.22 AAZ33797.1 - 0.11 12.2 0.2 0.27 10.8 0.1 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 AAZ33797.1 - 0.11 12.6 0.3 0.19 11.9 0.3 1.7 1 1 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 AAZ33797.1 - 0.13 12.0 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Thymidylate kinase Lum_binding PF00677.17 AAZ33797.1 - 0.16 11.9 0.1 0.4 10.7 0.1 1.6 1 0 0 1 1 1 0 Lumazine binding domain PRA-PH PF01503.17 AAZ33798.1 - 4.1e-15 56.0 0.1 5e-15 55.7 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase Med25_VWA PF11265.8 AAZ33798.1 - 0.015 15.1 0.0 0.017 15.0 0.0 1.0 1 0 0 1 1 1 0 Mediator complex subunit 25 von Willebrand factor type A TerC PF03741.16 AAZ33799.1 - 8.4e-51 172.2 17.6 1.1e-50 171.9 17.6 1.1 1 0 0 1 1 1 1 Integral membrane protein TerC family Gate PF07670.14 AAZ33799.1 - 0.0042 17.3 0.4 0.0042 17.3 0.4 2.4 1 1 1 2 2 2 1 Nucleoside recognition Ubie_methyltran PF01209.18 AAZ33800.1 - 8.6e-99 329.6 0.0 1.1e-98 329.3 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 AAZ33800.1 - 4.1e-24 85.1 0.0 8.4e-24 84.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAZ33800.1 - 1.6e-22 79.9 0.0 2.5e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAZ33800.1 - 6e-21 74.9 0.0 1.3e-20 73.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAZ33800.1 - 1.2e-16 61.0 0.0 1.6e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAZ33800.1 - 8.9e-13 48.8 0.0 1.6e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 AAZ33800.1 - 7.8e-08 32.3 0.0 1.7e-07 31.2 0.0 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 AAZ33800.1 - 0.00014 21.0 0.0 0.00019 20.6 0.0 1.4 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase MetW PF07021.12 AAZ33800.1 - 0.0003 20.4 0.0 0.00054 19.6 0.0 1.4 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 AAZ33800.1 - 0.00032 20.3 0.0 0.00055 19.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 AAZ33800.1 - 0.00041 19.7 0.0 0.00053 19.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain UPF0020 PF01170.18 AAZ33800.1 - 0.001 18.8 0.0 0.0031 17.2 0.0 1.9 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_8 PF05148.15 AAZ33800.1 - 0.0017 18.3 0.0 0.0029 17.5 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase GCD14 PF08704.10 AAZ33800.1 - 0.0043 16.8 0.0 0.027 14.1 0.0 1.9 1 1 1 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Methyltr_RsmB-F PF01189.17 AAZ33800.1 - 0.0055 16.4 0.0 0.018 14.6 0.0 1.8 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F ABC_tran PF00005.27 AAZ33801.1 - 2e-49 167.6 1.5 1e-23 84.4 0.0 3.6 4 0 0 4 4 4 2 ABC transporter ABC_tran_Xtn PF12848.7 AAZ33801.1 - 7.8e-27 93.1 11.0 7.8e-27 93.1 11.0 3.0 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 AAZ33801.1 - 6.7e-14 52.4 13.4 0.00025 21.0 0.2 4.4 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAZ33801.1 - 1.5e-10 40.9 0.1 0.0095 15.4 0.0 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 AAZ33801.1 - 1.7e-06 28.1 0.1 0.012 15.5 0.1 2.8 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 AAZ33801.1 - 6.7e-06 25.8 0.4 0.063 13.0 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 AAZ33801.1 - 3.2e-05 24.4 12.5 0.025 15.0 0.1 3.7 3 1 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.23 AAZ33801.1 - 4.5e-05 23.5 0.1 0.12 12.4 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_33 PF13671.6 AAZ33801.1 - 7.2e-05 23.0 9.1 0.045 13.9 0.0 4.3 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.6 AAZ33801.1 - 0.00015 22.3 0.1 0.022 15.3 0.0 3.4 3 0 0 3 3 3 1 AAA domain ATG16 PF08614.11 AAZ33801.1 - 0.00031 21.0 12.6 0.00031 21.0 12.6 2.5 3 0 0 3 3 2 1 Autophagy protein 16 (ATG16) MeaB PF03308.16 AAZ33801.1 - 0.00055 19.0 0.3 0.031 13.3 0.1 2.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB KAP_NTPase PF07693.14 AAZ33801.1 - 0.00069 19.0 0.0 0.25 10.5 0.0 2.5 2 1 0 2 2 2 1 KAP family P-loop domain DLIC PF05783.11 AAZ33801.1 - 0.001 18.0 0.2 0.48 9.2 0.0 2.3 2 0 0 2 2 2 2 Dynein light intermediate chain (DLIC) DUF815 PF05673.13 AAZ33801.1 - 0.0016 17.6 0.0 0.35 10.0 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 AAZ33801.1 - 0.0051 17.1 2.5 0.44 10.8 0.0 3.8 4 1 0 4 4 3 1 AAA domain AAA_30 PF13604.6 AAZ33801.1 - 0.0061 16.3 4.8 0.78 9.4 0.0 4.0 3 2 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 AAZ33801.1 - 0.0078 15.5 0.2 2.7 7.2 0.1 2.6 2 0 0 2 2 2 1 Zeta toxin ABC_tran_CTD PF16326.5 AAZ33801.1 - 0.0096 16.1 8.4 0.0096 16.1 8.4 5.0 3 2 1 4 4 4 1 ABC transporter C-terminal domain AAA_24 PF13479.6 AAZ33801.1 - 0.013 15.3 1.0 0.45 10.2 0.0 3.0 4 0 0 4 4 2 0 AAA domain RNA_helicase PF00910.22 AAZ33801.1 - 0.017 15.5 0.0 0.46 10.9 0.0 2.5 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 AAZ33801.1 - 0.02 14.8 0.6 0.61 10.0 0.0 3.2 3 0 0 3 3 3 0 NACHT domain AAA PF00004.29 AAZ33801.1 - 0.022 15.2 0.0 0.32 11.4 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.23 AAZ33801.1 - 0.034 14.2 0.8 3.6 7.6 0.0 3.4 4 0 0 4 4 4 0 Dynamin family Mg_chelatase PF01078.21 AAZ33801.1 - 0.069 12.5 0.7 8.1 5.8 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Roc PF08477.13 AAZ33801.1 - 0.07 13.3 0.0 5.9 7.1 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 AAZ33801.1 - 0.071 12.6 0.0 1.7 8.1 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Rad17 PF03215.15 AAZ33801.1 - 0.083 12.8 0.0 0.28 11.1 0.0 1.8 2 0 0 2 2 1 0 Rad17 P-loop domain AAA_5 PF07728.14 AAZ33801.1 - 0.09 12.8 0.1 7 6.6 0.1 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MukB PF04310.12 AAZ33801.1 - 0.13 12.1 0.2 16 5.2 0.0 2.5 2 0 0 2 2 2 0 MukB N-terminal AAA_28 PF13521.6 AAZ33801.1 - 0.13 12.5 0.0 0.13 12.5 0.0 3.5 4 0 0 4 4 2 0 AAA domain AAA_23 PF13476.6 AAZ33801.1 - 0.15 12.5 25.7 0.28 11.6 0.0 4.6 4 1 0 4 4 3 0 AAA domain DUF572 PF04502.13 AAZ33801.1 - 1.8 8.1 8.2 0.28 10.8 0.9 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) AAA_25 PF13481.6 AAZ33801.1 - 2 8.0 5.8 7.6 6.1 0.0 3.6 3 1 0 3 3 2 0 AAA domain Laminin_II PF06009.12 AAZ33801.1 - 2.1 8.3 12.5 3.2 7.8 0.9 2.4 2 0 0 2 2 2 0 Laminin Domain II AAA_15 PF13175.6 AAZ33801.1 - 3.1 7.4 8.1 4.6 6.8 0.0 3.6 5 0 0 5 5 5 0 AAA ATPase domain FliD_N PF02465.18 AAZ33801.1 - 3.4 8.4 9.3 0.16 12.7 1.5 2.4 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Thymidylate_kin PF02223.17 AAZ33801.1 - 7.5 6.2 7.9 10 5.8 0.0 3.1 3 0 0 3 3 3 0 Thymidylate kinase Dus PF01207.17 AAZ33802.1 - 3.4e-66 223.4 0.0 8.5e-66 222.1 0.0 1.5 1 1 0 2 2 2 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 AAZ33802.1 - 0.006 16.1 0.0 0.0093 15.5 0.0 1.2 1 0 0 1 1 1 1 Histidine biosynthesis protein tRNA-synt_1c PF00749.21 AAZ33803.1 - 3.6e-109 364.5 0.0 4.6e-109 364.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 AAZ33803.1 - 3.5e-62 209.3 0.0 5.9e-62 208.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain HTH_3 PF01381.22 AAZ33804.1 - 8.5e-13 48.2 0.1 7.6e-12 45.1 0.0 1.9 1 1 1 2 2 2 1 Helix-turn-helix HTH_31 PF13560.6 AAZ33804.1 - 4.6e-11 42.9 0.1 5.3e-11 42.7 0.1 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 AAZ33804.1 - 3.7e-08 33.3 0.0 4.3e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 AAZ33804.1 - 1.1e-05 25.7 0.1 2.7e-05 24.5 0.0 1.6 1 1 1 2 2 2 1 Cro/C1-type HTH DNA-binding domain HTH_37 PF13744.6 AAZ33804.1 - 0.00056 19.8 0.0 0.00077 19.4 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 AAZ33804.1 - 0.0084 16.0 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain DUF3450 PF11932.8 AAZ33805.1 - 1.9e-05 24.1 2.9 2.4e-05 23.8 2.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) DUF4200 PF13863.6 AAZ33805.1 - 0.00046 20.6 2.5 0.00072 19.9 1.8 1.5 1 1 1 2 2 2 1 Domain of unknown function (DUF4200) Seryl_tRNA_N PF02403.22 AAZ33805.1 - 0.00052 20.2 1.3 0.00066 19.9 1.3 1.1 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DUF641 PF04859.12 AAZ33805.1 - 0.00055 20.3 1.5 0.00065 20.0 1.5 1.0 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) Fib_alpha PF08702.10 AAZ33805.1 - 0.0026 18.0 0.1 0.0033 17.6 0.1 1.1 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family Med21 PF11221.8 AAZ33805.1 - 0.0032 17.7 0.4 0.0039 17.4 0.4 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex YvrJ PF12841.7 AAZ33805.1 - 0.0038 16.7 0.2 0.0073 15.8 0.0 1.6 2 0 0 2 2 2 1 YvrJ protein family ADIP PF11559.8 AAZ33805.1 - 0.0045 17.1 0.6 0.0054 16.8 0.6 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Jnk-SapK_ap_N PF09744.9 AAZ33805.1 - 0.0079 16.4 0.9 0.0095 16.2 0.9 1.1 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 CALCOCO1 PF07888.11 AAZ33805.1 - 0.008 15.1 3.0 0.0089 14.9 3.0 1.0 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like DUF812 PF05667.11 AAZ33805.1 - 0.0084 15.1 0.6 0.0095 14.9 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF16 PF01519.16 AAZ33805.1 - 0.013 15.9 0.4 0.035 14.6 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF1664 PF07889.12 AAZ33805.1 - 0.015 15.3 0.6 0.02 15.0 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Phage_GPO PF05929.11 AAZ33805.1 - 0.016 14.8 2.3 0.018 14.7 2.3 1.0 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase COG5 PF10392.9 AAZ33805.1 - 0.017 15.3 0.1 0.021 15.0 0.1 1.2 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DUF724 PF05266.14 AAZ33805.1 - 0.018 14.9 0.9 0.023 14.5 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) SlyX PF04102.12 AAZ33805.1 - 0.027 15.1 1.8 0.045 14.4 0.1 2.0 1 1 0 2 2 2 0 SlyX UPF0184 PF03670.13 AAZ33805.1 - 0.027 14.8 1.6 0.097 13.1 1.4 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) Troponin PF00992.20 AAZ33805.1 - 0.033 14.5 1.1 0.041 14.2 1.1 1.2 1 0 0 1 1 1 0 Troponin ERM PF00769.19 AAZ33805.1 - 0.035 13.9 4.5 0.042 13.7 4.5 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Syntaxin-6_N PF09177.11 AAZ33805.1 - 0.035 14.6 0.5 0.044 14.3 0.5 1.1 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Imm58 PF15581.6 AAZ33805.1 - 0.036 14.2 0.0 0.045 13.9 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 58 TMF_DNA_bd PF12329.8 AAZ33805.1 - 0.042 13.8 0.7 0.11 12.5 0.3 1.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding TMCO5 PF14992.6 AAZ33805.1 - 0.057 13.0 0.3 0.065 12.8 0.3 1.1 1 0 0 1 1 1 0 TMCO5 family Atg14 PF10186.9 AAZ33805.1 - 0.067 12.3 1.4 0.073 12.1 1.4 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF948 PF06103.11 AAZ33805.1 - 0.077 13.3 0.5 0.12 12.6 0.5 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Tup_N PF08581.10 AAZ33805.1 - 0.087 13.1 1.3 0.18 12.1 1.3 1.5 1 1 0 1 1 1 0 Tup N-terminal DivIC PF04977.15 AAZ33805.1 - 0.31 10.9 4.0 0.33 10.8 0.1 2.1 1 1 1 2 2 2 0 Septum formation initiator DctP PF03480.13 AAZ33806.1 - 5.2e-75 252.4 0.0 6.6e-75 252.1 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein, family 7 AIM24 PF01987.17 AAZ33807.1 - 2.7e-66 223.2 1.8 3.1e-66 223.0 1.8 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Cupin_3 PF05899.12 AAZ33808.1 - 3e-24 84.5 0.2 3.9e-24 84.1 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Ppnp PF06865.11 AAZ33808.1 - 0.0014 19.0 0.0 0.0019 18.6 0.0 1.2 1 0 0 1 1 1 1 Pyrimidine/purine nucleoside phosphorylase EutQ PF06249.12 AAZ33808.1 - 0.0098 15.7 0.0 0.011 15.5 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_2 PF07883.11 AAZ33808.1 - 0.046 13.4 0.0 0.076 12.7 0.0 1.3 1 0 0 1 1 1 0 Cupin domain PBP_like_2 PF12849.7 AAZ33809.1 - 1.2e-35 123.6 0.4 2.2e-35 122.7 0.4 1.4 1 1 0 1 1 1 1 PBP superfamily domain PBP_like PF12727.7 AAZ33809.1 - 9.9e-11 41.1 0.0 1.4e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 PBP superfamily domain SBP_bac_11 PF13531.6 AAZ33809.1 - 5.7e-08 32.8 0.4 4.7e-07 29.8 0.2 2.4 1 1 1 2 2 2 1 Bacterial extracellular solute-binding protein LysR_substrate PF03466.20 AAZ33809.1 - 0.027 13.9 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 LysR substrate binding domain BPD_transp_2 PF02653.16 AAZ33810.1 - 1.3e-29 103.2 39.2 1.5e-29 103.0 39.2 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component Orn_Arg_deC_N PF02784.16 AAZ33811.1 - 2.8e-44 151.3 0.0 4e-44 150.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Arg_decarb_HB PF17810.1 AAZ33811.1 - 2e-21 76.1 0.1 5.2e-21 74.7 0.1 1.8 1 0 0 1 1 1 1 Arginine decarboxylase helical bundle domain Arg_decarbox_C PF17944.1 AAZ33811.1 - 7.3e-15 55.3 0.2 2.2e-14 53.7 0.2 1.9 1 0 0 1 1 1 1 Arginine decarboxylase C-terminal helical extension DUF2383 PF09537.10 AAZ33812.1 - 1.7e-41 141.0 0.7 2.5e-41 140.5 0.4 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF2383) Ferritin PF00210.24 AAZ33812.1 - 0.019 14.9 0.2 0.035 14.1 0.1 1.3 1 1 0 1 1 1 0 Ferritin-like domain HrpB2 PF09487.10 AAZ33812.1 - 0.027 14.9 0.3 0.49 10.8 0.1 2.2 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB2) DUF406 PF04175.12 AAZ33812.1 - 0.048 14.1 0.3 0.14 12.7 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF406) Oleosin PF01277.17 AAZ33813.1 - 0.03 14.1 0.4 0.037 13.8 0.4 1.1 1 0 0 1 1 1 0 Oleosin RPN2_C PF18004.1 AAZ33813.1 - 0.059 13.3 12.2 0.067 13.1 12.2 1.0 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Ureide_permease PF07168.11 AAZ33813.1 - 0.18 10.5 4.8 0.19 10.4 4.8 1.0 1 0 0 1 1 1 0 Ureide permease FemAB PF02388.16 AAZ33813.1 - 0.25 10.2 6.3 0.26 10.1 6.3 1.0 1 0 0 1 1 1 0 FemAB family R_equi_Vir PF05526.11 AAZ33813.1 - 0.27 11.1 3.7 0.29 11.0 3.7 1.2 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein EMC3_TMCO1 PF01956.16 AAZ33813.1 - 0.3 10.8 1.6 0.31 10.8 1.6 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF4192 PF13830.6 AAZ33813.1 - 0.49 10.4 4.2 0.52 10.3 4.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Connexin PF00029.19 AAZ33813.1 - 0.54 10.0 2.6 0.56 9.9 2.6 1.1 1 0 0 1 1 1 0 Connexin Spt20 PF12090.8 AAZ33813.1 - 0.62 9.6 9.6 0.71 9.4 9.6 1.0 1 0 0 1 1 1 0 Spt20 family O-antigen_lig PF13425.6 AAZ33813.1 - 0.73 8.5 2.6 0.84 8.4 2.6 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein SID-1_RNA_chan PF13965.6 AAZ33813.1 - 0.97 7.8 3.0 0.93 7.8 3.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF913 PF06025.12 AAZ33813.1 - 1.2 8.0 6.6 1.3 7.9 6.6 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) AIF_C PF14721.6 AAZ33813.1 - 1.3 9.4 5.7 1.5 9.2 5.7 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term CPSF100_C PF13299.6 AAZ33813.1 - 1.3 9.2 8.8 1.4 9.1 8.8 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF3138 PF11336.8 AAZ33813.1 - 1.4 7.4 7.7 1.5 7.4 7.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Presenilin PF01080.17 AAZ33813.1 - 1.8 7.3 7.9 1.7 7.3 7.9 1.0 1 0 0 1 1 1 0 Presenilin LPAM_2 PF13627.6 AAZ33813.1 - 2.4 8.1 5.3 3.2 7.7 5.3 1.2 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site CLN3 PF02487.17 AAZ33813.1 - 3.8 6.5 4.2 3.9 6.4 4.2 1.0 1 0 0 1 1 1 0 CLN3 protein Hid1 PF12722.7 AAZ33813.1 - 4.2 5.4 8.4 4.3 5.3 8.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Conotoxin PF02950.17 AAZ33813.1 - 6.8 7.8 6.3 30 5.7 6.3 1.9 1 1 0 1 1 1 0 Conotoxin RNA_pol_Rpc4 PF05132.14 AAZ33813.1 - 6.8 7.1 10.7 8.4 6.8 10.7 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Tim54 PF11711.8 AAZ33813.1 - 9.1 4.9 11.4 10 4.8 11.4 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Amidase_2 PF01510.25 AAZ33814.1 - 1e-30 106.7 0.0 1.7e-30 106.1 0.0 1.3 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase PG_binding_1 PF01471.18 AAZ33814.1 - 1.3e-08 34.9 0.1 2e-08 34.3 0.1 1.3 1 0 0 1 1 1 1 Putative peptidoglycan binding domain PG_binding_2 PF08823.11 AAZ33814.1 - 0.046 14.0 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Putative peptidoglycan binding domain Fungal_lectin PF07938.12 AAZ33814.1 - 0.062 12.7 0.0 0.088 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal fucose-specific lectin MCPsignal PF00015.21 AAZ33815.1 - 1.1e-44 152.3 44.1 2.7e-43 147.8 22.4 3.5 2 1 1 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain NIT PF08376.10 AAZ33815.1 - 1.7e-38 133.4 0.0 1.7e-38 133.4 0.0 3.5 2 1 1 3 3 2 1 Nitrate and nitrite sensing HAMP PF00672.25 AAZ33815.1 - 0.00012 22.4 0.7 0.00089 19.6 0.1 3.0 2 0 0 2 2 2 1 HAMP domain CD225 PF04505.12 AAZ33815.1 - 0.037 14.2 2.4 1.4 9.1 0.0 3.0 2 0 0 2 2 2 0 Interferon-induced transmembrane protein Syntaxin_2 PF14523.6 AAZ33815.1 - 0.16 12.3 17.3 0.095 13.1 0.8 5.2 3 2 1 5 5 5 0 Syntaxin-like protein UPF0242 PF06785.11 AAZ33815.1 - 0.65 10.1 4.0 4.8 7.2 0.4 2.9 2 2 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Goodbye PF17109.5 AAZ33815.1 - 7.2 7.1 7.7 11 6.5 0.3 3.4 3 1 0 3 3 3 0 fungal STAND N-terminal Goodbye domain Arfaptin PF06456.13 AAZ33815.1 - 7.6 6.0 7.0 3.9 7.0 0.1 2.8 2 1 1 3 3 3 0 Arfaptin-like domain COG2 PF06148.11 AAZ33815.1 - 8.7 6.4 15.6 1.1 9.4 0.3 4.8 3 3 2 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 Folliculin PF11704.8 AAZ33815.1 - 9 6.1 9.6 20 5.0 2.0 2.7 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport DUF1664 PF07889.12 AAZ33815.1 - 9.5 6.3 19.3 0.064 13.3 2.6 4.3 3 3 2 5 5 5 0 Protein of unknown function (DUF1664) SAICAR_synt PF01259.18 AAZ33816.1 - 1.6e-65 221.3 0.0 1.8e-65 221.1 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase IF2_N PF04760.15 AAZ33816.1 - 0.022 14.5 0.2 0.45 10.4 0.1 2.7 3 0 0 3 3 3 0 Translation initiation factor IF-2, N-terminal region Sigma70_r4_2 PF08281.12 AAZ33817.1 - 6e-14 51.5 0.4 1.2e-13 50.4 0.4 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 AAZ33817.1 - 3.9e-13 49.0 0.2 7e-13 48.1 0.2 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_ECF PF07638.11 AAZ33817.1 - 3.7e-09 36.7 0.4 1.1e-08 35.2 0.1 1.7 1 1 1 2 2 2 1 ECF sigma factor Sigma70_r4 PF04545.16 AAZ33817.1 - 4.3e-08 32.5 1.3 8.3e-08 31.6 0.2 2.0 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_23 PF13384.6 AAZ33817.1 - 0.00027 20.6 0.0 0.0007 19.3 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain GerE PF00196.19 AAZ33817.1 - 0.00038 20.0 0.1 0.00064 19.2 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_38 PF13936.6 AAZ33817.1 - 0.00043 20.0 0.0 0.00084 19.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_11 PF08279.12 AAZ33817.1 - 0.0095 15.9 0.1 0.019 14.9 0.1 1.6 1 0 0 1 1 1 1 HTH domain HTH_AsnC-type PF13404.6 AAZ33817.1 - 0.014 15.2 0.1 0.051 13.4 0.0 2.0 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain DUF3731 PF12531.8 AAZ33817.1 - 0.014 15.2 0.6 0.024 14.5 0.6 1.4 1 1 0 1 1 1 0 DNA-K related protein HTH_Tnp_ISL3 PF13542.6 AAZ33817.1 - 0.027 13.9 0.1 0.1 12.1 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 UPF0122 PF04297.14 AAZ33817.1 - 0.04 14.2 0.0 0.068 13.4 0.0 1.3 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like Fe_dep_repress PF01325.19 AAZ33817.1 - 0.05 13.8 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_28 PF13518.6 AAZ33817.1 - 0.051 13.7 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain FAD-SLDH PF12318.8 AAZ33817.1 - 0.11 12.5 0.8 2.4 8.2 0.0 2.1 1 1 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase HTH_20 PF12840.7 AAZ33817.1 - 0.17 11.9 2.2 0.45 10.6 0.0 2.6 3 2 0 3 3 3 0 Helix-turn-helix domain Amidohydro_1 PF01979.20 AAZ33818.1 - 2.7e-22 79.6 0.5 2e-21 76.7 0.5 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AAZ33818.1 - 2.3e-21 76.8 5.9 3.7e-16 59.6 1.2 2.2 1 1 1 2 2 2 2 Amidohydrolase family AA_kinase PF00696.28 AAZ33818.1 - 0.044 13.4 0.3 1 8.9 0.3 2.2 1 1 0 1 1 1 0 Amino acid kinase family Methyltransf_32 PF13679.6 AAZ33819.1 - 3.2e-27 95.5 1.2 1.2e-26 93.6 1.2 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAZ33819.1 - 3.9e-10 39.7 0.0 6.1e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAZ33819.1 - 1.9e-06 28.5 0.1 4.5e-06 27.3 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAZ33819.1 - 0.00019 22.0 0.1 0.00041 20.9 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 AAZ33819.1 - 0.001 18.9 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TRM13 PF05206.14 AAZ33819.1 - 0.0084 15.7 5.5 1.8 8.0 0.0 3.3 1 1 1 2 2 2 2 Methyltransferase TRM13 RrnaAD PF00398.20 AAZ33819.1 - 0.048 12.7 0.0 0.077 12.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase BPD_transp_1 PF00528.22 AAZ33820.1 - 3.2e-17 62.8 14.0 3.4e-17 62.8 13.5 1.3 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component PAD_porph PF04371.15 AAZ33821.1 - 1.4e-123 412.3 0.0 1.6e-123 412.1 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase Amidinotransf PF02274.17 AAZ33821.1 - 0.11 11.6 0.0 1.7 7.6 0.0 2.2 2 0 0 2 2 2 0 Amidinotransferase CitMHS PF03600.16 AAZ33822.1 - 1.8e-51 175.1 49.4 1.8e-51 175.1 49.4 2.2 2 1 0 2 2 2 1 Citrate transporter Transposase_mut PF00872.18 AAZ33823.1 - 1.5e-112 376.3 0.0 1.7e-112 376.1 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ33823.1 - 6e-05 23.4 0.0 0.00016 22.0 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain DUF4844 PF16133.5 AAZ33823.1 - 0.18 12.3 0.0 0.44 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) PAAR_motif PF05488.13 AAZ33824.1 - 6.8e-17 61.4 2.5 1.3e-16 60.5 1.4 1.8 2 0 0 2 2 2 1 PAAR motif BPL_LplA_LipB PF03099.19 AAZ33825.1 - 8.8e-18 64.5 0.0 1.6e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family HTH_11 PF08279.12 AAZ33825.1 - 2.8e-10 40.0 0.0 6.2e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 HTH domain HTH_1 PF00126.27 AAZ33825.1 - 1.6e-05 24.7 0.2 6.3e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family BPL_C PF02237.17 AAZ33825.1 - 0.0011 18.8 0.2 0.0039 17.0 0.2 2.0 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain HTH_24 PF13412.6 AAZ33825.1 - 0.0026 17.3 0.0 0.0052 16.3 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Cadherin_2 PF08266.12 AAZ33825.1 - 0.013 15.3 0.2 2.1 8.3 0.0 2.8 3 0 0 3 3 3 0 Cadherin-like HTH_AsnC-type PF13404.6 AAZ33825.1 - 0.029 14.2 0.0 0.059 13.2 0.0 1.6 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain SIR2 PF02146.17 AAZ33827.1 - 1.4e-46 158.7 0.0 1.7e-46 158.4 0.0 1.1 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 AAZ33827.1 - 0.0037 17.0 0.1 0.031 14.0 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TetR_N PF00440.23 AAZ33828.1 - 4.9e-15 55.0 0.4 7.8e-15 54.4 0.4 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_Tnp_1_2 PF13022.6 AAZ33828.1 - 0.0036 17.5 0.0 0.005 17.0 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix of insertion element transposase HTH_23 PF13384.6 AAZ33828.1 - 0.012 15.4 0.0 0.045 13.6 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain HTH_7 PF02796.15 AAZ33828.1 - 0.019 15.1 0.0 0.048 13.7 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_20 PF12840.7 AAZ33828.1 - 0.037 14.1 0.0 5.1 7.2 0.0 2.7 2 1 1 3 3 3 0 Helix-turn-helix domain ABC2_membrane_2 PF12679.7 AAZ33829.1 - 0.0044 16.3 0.3 0.0056 16.0 0.3 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein 7tm_3 PF00003.22 AAZ33829.1 - 0.0064 16.3 1.6 0.0088 15.8 1.6 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Terminase_6 PF03237.15 AAZ33830.1 - 1.1e-16 61.2 0.1 1.2e-16 61.0 0.1 1.0 1 0 0 1 1 1 1 Terminase-like family Coat_F PF07875.12 AAZ33831.1 - 0.038 14.2 0.8 1.2 9.4 0.0 3.0 3 0 0 3 3 3 0 Coat F domain EPSP_synthase PF00275.20 AAZ33832.1 - 4.4e-119 397.9 2.5 5e-119 397.7 2.5 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) TrmE_N PF10396.9 AAZ33832.1 - 0.059 13.7 0.0 0.35 11.2 0.0 2.3 2 0 0 2 2 2 0 GTP-binding protein TrmE N-terminus TonB_dep_Rec PF00593.24 AAZ33833.1 - 1.8e-50 173.2 30.5 1.8e-50 173.2 30.5 2.5 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 AAZ33833.1 - 5.2e-17 62.4 0.3 1.5e-16 60.9 0.3 1.8 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain Acyltransferase PF01553.21 AAZ33834.1 - 3.5e-17 62.3 0.0 5.8e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 AAZ33834.1 - 0.0024 17.9 1.1 0.011 15.9 1.1 2.0 1 1 0 1 1 1 1 Acyltransferase C-terminus PAP2 PF01569.21 AAZ33835.1 - 1e-19 70.7 8.0 1e-19 70.7 8.0 3.5 3 1 0 3 3 3 1 PAP2 superfamily SNARE_assoc PF09335.11 AAZ33835.1 - 1.4e-18 67.6 4.1 1.4e-18 67.6 4.1 3.5 3 1 0 3 3 3 1 SNARE associated Golgi protein PAP2_3 PF14378.6 AAZ33835.1 - 5.7e-05 22.9 26.7 0.00044 20.0 13.5 3.9 2 1 0 3 3 3 2 PAP2 superfamily ChlI PF13541.6 AAZ33836.1 - 1.5e-43 147.4 0.0 2.2e-43 147.0 0.0 1.2 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase Mg_chelatase PF01078.21 AAZ33836.1 - 7.2e-37 126.8 0.1 1.1e-36 126.1 0.1 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Lon_C PF05362.13 AAZ33836.1 - 5.1e-07 29.4 0.1 7.2e-07 29.0 0.1 1.2 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 AAZ33836.1 - 0.002 18.6 0.0 0.0039 17.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AAZ33836.1 - 0.0049 17.3 0.1 0.015 15.7 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 AAZ33836.1 - 0.032 14.2 0.0 0.054 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 AAZ33836.1 - 0.062 13.6 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain SAT PF16073.5 AAZ33836.1 - 0.066 12.9 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis IstB_IS21 PF01695.17 AAZ33836.1 - 0.099 12.4 0.1 0.22 11.2 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 AAZ33836.1 - 0.12 12.6 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 AAZ33836.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain T2SSE PF00437.20 AAZ33836.1 - 0.14 11.2 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 AAZ33836.1 - 0.17 11.4 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_11 PF13086.6 AAZ33836.1 - 0.17 11.6 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 AAZ33836.1 - 0.24 10.6 0.0 1 8.5 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) GGDEF PF00990.21 AAZ33837.1 - 3.2e-42 144.0 0.0 5.1e-42 143.3 0.0 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_3 PF08447.12 AAZ33837.1 - 6.7e-21 74.4 0.1 1.3e-20 73.5 0.1 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AAZ33837.1 - 1e-05 25.7 0.0 4.7e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 AAZ33837.1 - 0.0007 19.8 0.1 0.012 15.9 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 AAZ33837.1 - 0.0025 17.8 0.0 0.047 13.7 0.0 2.5 2 0 0 2 2 2 1 PAS domain GGDEF_2 PF17853.1 AAZ33837.1 - 0.033 14.4 0.1 0.29 11.4 0.0 2.2 2 0 0 2 2 2 0 GGDEF-like domain PAS PF00989.25 AAZ33837.1 - 0.089 12.8 0.0 0.23 11.5 0.0 1.8 1 0 0 1 1 1 0 PAS fold RuvA_N PF01330.21 AAZ33838.1 - 1.7e-23 82.5 0.0 3.4e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 RuvA N terminal domain HHH_5 PF14520.6 AAZ33838.1 - 1.6e-19 70.3 0.8 5.4e-18 65.4 0.1 3.1 3 1 0 3 3 3 1 Helix-hairpin-helix domain RuvA_C PF07499.13 AAZ33838.1 - 5.3e-16 58.8 2.2 6.9e-16 58.4 0.5 2.0 2 0 0 2 2 2 1 RuvA, C-terminal domain HHH PF00633.23 AAZ33838.1 - 1.5e-07 30.9 0.5 0.0031 17.3 0.0 3.2 4 0 0 4 4 4 2 Helix-hairpin-helix motif IMS_HHH PF11798.8 AAZ33838.1 - 0.00027 21.1 0.0 0.011 16.0 0.0 2.7 3 0 0 3 3 3 1 IMS family HHH motif HHH_8 PF14716.6 AAZ33838.1 - 0.0005 20.4 0.3 0.19 12.1 0.0 3.6 3 1 1 4 4 4 1 Helix-hairpin-helix domain Transposase_20 PF02371.16 AAZ33838.1 - 0.00058 20.1 0.0 0.015 15.6 0.0 2.2 2 0 0 2 2 2 1 Transposase IS116/IS110/IS902 family Cdd1 PF11731.8 AAZ33838.1 - 0.012 15.9 0.0 0.58 10.4 0.0 2.9 3 0 0 3 3 3 0 Pathogenicity locus Ribosomal_S13 PF00416.22 AAZ33838.1 - 0.017 15.5 0.0 3.2 8.2 0.0 2.3 1 1 1 2 2 2 0 Ribosomal protein S13/S18 HHH_2 PF12826.7 AAZ33838.1 - 0.022 14.8 0.0 12 6.1 0.0 2.9 2 1 0 3 3 3 0 Helix-hairpin-helix motif HHH_3 PF12836.7 AAZ33838.1 - 0.023 15.0 0.0 2 8.7 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif 5_3_exonuc PF01367.20 AAZ33838.1 - 0.029 15.0 0.0 0.66 10.6 0.0 2.3 1 1 1 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DNA_pol_lambd_f PF10391.9 AAZ33838.1 - 0.091 12.6 0.0 0.98 9.3 0.0 2.3 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda T2SSE PF00437.20 AAZ33839.1 - 4.6e-85 285.0 0.6 6.2e-85 284.6 0.6 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein Zeta_toxin PF06414.12 AAZ33839.1 - 0.0015 17.8 0.0 0.0045 16.3 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_7 PF12775.7 AAZ33839.1 - 0.0029 17.2 0.1 0.0049 16.4 0.1 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_30 PF13604.6 AAZ33839.1 - 0.0044 16.8 0.0 0.0075 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.18 AAZ33839.1 - 0.0044 16.4 0.0 0.0096 15.3 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family Mg_chelatase PF01078.21 AAZ33839.1 - 0.0085 15.5 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 AAZ33839.1 - 0.009 16.1 0.0 0.024 14.8 0.0 1.6 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_28 PF13521.6 AAZ33839.1 - 0.0091 16.2 0.0 0.021 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAZ33839.1 - 0.011 16.1 0.0 0.021 15.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 AAZ33839.1 - 0.012 16.0 0.0 0.028 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AAZ33839.1 - 0.018 14.8 0.1 0.052 13.3 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 AAZ33839.1 - 0.025 15.1 0.0 0.045 14.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter ATPase PF06745.13 AAZ33839.1 - 0.027 13.8 0.1 0.48 9.7 0.0 2.4 2 0 0 2 2 2 0 KaiC Sigma54_activat PF00158.26 AAZ33839.1 - 0.031 14.0 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.14 AAZ33839.1 - 0.066 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TrwB_AAD_bind PF10412.9 AAZ33839.1 - 0.094 11.6 0.1 0.16 10.9 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_18 PF13238.6 AAZ33839.1 - 0.11 13.0 0.0 0.24 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 AAZ33839.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase Septin PF00735.18 AAZ33839.1 - 0.2 10.9 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 Septin Lipoprotein_9 PF03180.14 AAZ33840.1 - 2e-96 321.7 0.1 2.2e-96 321.5 0.1 1.0 1 0 0 1 1 1 1 NLPA lipoprotein Phosphonate-bd PF12974.7 AAZ33840.1 - 6.1e-08 32.6 0.0 3.8e-05 23.4 0.0 2.2 2 0 0 2 2 2 2 ABC transporter, phosphonate, periplasmic substrate-binding protein YscJ_FliF PF01514.17 AAZ33842.1 - 2.8e-30 105.4 0.0 4.5e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 Secretory protein of YscJ/FliF family Glyco_tranf_2_3 PF13641.6 AAZ33843.1 - 1.6e-50 172.2 0.1 2.2e-50 171.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 AAZ33843.1 - 9.1e-32 110.6 2.3 2.4e-31 109.2 2.3 1.7 1 0 0 1 1 1 1 Glycosyl transferase family group 2 EamA PF00892.20 AAZ33844.1 - 7e-12 45.7 32.9 1.1e-10 41.9 13.3 2.3 1 1 0 2 2 2 2 EamA-like transporter family Phage_holin_2_4 PF16082.5 AAZ33844.1 - 5.2 6.9 8.3 28 4.6 0.9 3.5 2 1 1 3 3 3 0 Bacteriophage holin family, superfamily II-like Aminotran_3 PF00202.21 AAZ33845.1 - 1.4e-79 267.7 0.0 2.1e-79 267.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III CP_ATPgrasp_2 PF14403.6 AAZ33846.1 - 2.3e-159 530.3 0.0 3.4e-159 529.8 0.0 1.3 1 0 0 1 1 1 1 Circularly permuted ATP-grasp type 2 CP_ATPgrasp_1 PF04174.13 AAZ33846.1 - 3.5e-120 401.0 0.0 5.6e-120 400.3 0.0 1.3 1 0 0 1 1 1 1 A circularly permuted ATPgrasp Alpha-E PF04168.12 AAZ33846.1 - 7.4e-67 226.2 4.7 1.3e-66 225.4 4.7 1.4 1 0 0 1 1 1 1 A predicted alpha-helical domain with a conserved ER motif. zf-MYND PF01753.18 AAZ33847.1 - 0.076 13.1 0.9 0.076 13.1 0.9 2.5 2 1 0 2 2 2 0 MYND finger HTH_30 PF13556.6 AAZ33848.1 - 6.7e-20 70.6 0.0 1.3e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_8 PF02954.19 AAZ33848.1 - 8.8e-05 22.2 0.0 0.00015 21.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family TruD PF01142.18 AAZ33849.1 - 2.8e-57 194.4 0.0 4.2e-39 134.6 0.0 2.0 1 1 1 2 2 2 2 tRNA pseudouridine synthase D (TruD) AAA_15 PF13175.6 AAZ33850.1 - 2.4e-13 50.5 0.0 2.4e-13 50.5 0.0 1.0 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 AAZ33850.1 - 8.9e-10 38.4 0.0 1e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AAZ33850.1 - 1e-08 35.4 0.1 1.2e-08 35.2 0.1 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AAZ33850.1 - 6.3e-06 26.8 0.0 7.6e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAZ33850.1 - 8.9e-05 22.2 0.0 0.00015 21.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF2813 PF11398.8 AAZ33850.1 - 0.00092 18.6 0.2 0.0011 18.4 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2813) AAA_27 PF13514.6 AAZ33850.1 - 0.03 13.9 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AAZ33850.1 - 0.057 13.9 0.0 0.071 13.6 0.0 1.2 1 0 0 1 1 1 0 ABC transporter SGL PF08450.12 AAZ33851.1 - 3.8e-78 262.5 0.1 1.2e-77 260.8 0.1 1.7 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 AAZ33851.1 - 0.0014 18.7 0.0 0.0039 17.3 0.0 1.7 1 0 0 1 1 1 1 Strictosidine synthase WD40 PF00400.32 AAZ33851.1 - 0.0093 16.8 1.2 0.65 11.0 0.0 3.7 3 1 0 3 3 3 1 WD domain, G-beta repeat Reg_prop PF07494.11 AAZ33851.1 - 0.014 15.6 4.4 9.2 6.9 0.0 4.4 3 1 1 4 4 4 0 Two component regulator propeller Arylesterase PF01731.20 AAZ33851.1 - 0.041 14.1 0.0 0.067 13.4 0.0 1.3 1 0 0 1 1 1 0 Arylesterase PD40 PF07676.12 AAZ33851.1 - 0.084 12.8 0.1 0.83 9.7 0.0 2.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Phytase-like PF13449.6 AAZ33851.1 - 0.23 11.4 0.0 0.4 10.6 0.0 1.3 1 0 0 1 1 1 0 Esterase-like activity of phytase NUDIX PF00293.28 AAZ33853.1 - 2.5e-11 43.7 0.1 2.9e-11 43.5 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain AAA_27 PF13514.6 AAZ33853.1 - 0.0076 15.9 0.0 0.01 15.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain Trp_Tyr_perm PF03222.13 AAZ33854.1 - 3e-13 49.6 27.5 3.9e-13 49.2 27.5 1.1 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family Hyr1 PF15789.5 AAZ33854.1 - 0.059 12.9 1.5 0.13 11.8 1.5 1.6 1 0 0 1 1 1 0 Hyphally regulated cell wall GPI-anchored protein 1 AA_permease_2 PF13520.6 AAZ33854.1 - 0.89 8.3 37.1 0.28 10.0 29.1 2.4 1 1 1 2 2 2 0 Amino acid permease TRIQK PF15168.6 AAZ33854.1 - 1.5 8.8 0.0 1.5 8.8 0.0 3.0 4 0 0 4 4 4 0 Triple QxxK/R motif-containing protein family 7TM_transglut PF14402.6 AAZ33855.1 - 5e-95 317.7 19.0 8.2e-95 317.0 19.0 1.3 1 0 0 1 1 1 1 7 transmembrane helices usually fused to an inactive transglutaminase Transglut_i_TM PF14400.6 AAZ33855.1 - 2.1e-46 157.9 0.0 4e-46 157.0 0.0 1.5 1 0 0 1 1 1 1 Inactive transglutaminase fused to 7 transmembrane helices TMEM154 PF15102.6 AAZ33855.1 - 3.7 7.4 4.5 0.67 9.8 0.3 2.0 2 0 0 2 2 2 0 TMEM154 protein family Multi_Drug_Res PF00893.19 AAZ33856.1 - 2.9e-07 31.0 2.0 4.4e-07 30.5 2.0 1.3 1 0 0 1 1 1 1 Small Multidrug Resistance protein EamA PF00892.20 AAZ33856.1 - 4.9e-05 23.5 9.2 5.6e-05 23.3 8.8 1.2 1 1 0 1 1 1 1 EamA-like transporter family HutD PF05962.11 AAZ33857.1 - 3e-53 180.5 0.0 3.6e-53 180.3 0.0 1.0 1 0 0 1 1 1 1 HutD HNH PF01844.23 AAZ33858.1 - 0.0002 21.5 1.4 0.00045 20.3 1.4 1.6 1 0 0 1 1 1 1 HNH endonuclease TilS PF09179.11 AAZ33858.1 - 0.12 12.9 0.0 0.23 12.0 0.0 1.4 1 0 0 1 1 1 0 TilS substrate binding domain Cytochrom_C_asm PF01578.20 AAZ33860.1 - 8.9e-26 91.0 21.9 1.6e-25 90.1 21.9 1.4 1 0 0 1 1 1 1 Cytochrome C assembly protein CbtB PF09489.10 AAZ33860.1 - 0.72 10.0 0.0 0.72 10.0 0.0 3.0 4 0 0 4 4 4 0 Probable cobalt transporter subunit (CbtB) 7tm_7 PF08395.12 AAZ33860.1 - 3.7 6.7 9.1 5.3 6.1 3.5 2.6 1 1 2 3 3 3 0 7tm Chemosensory receptor DUF2070 PF09843.9 AAZ33860.1 - 6.4 4.9 8.9 8 4.6 8.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) GFA PF04828.14 AAZ33861.1 - 7.9e-19 67.8 0.9 7.9e-19 67.8 0.9 1.3 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme BPD_transp_1 PF00528.22 AAZ33862.1 - 2.4e-16 60.0 7.3 2.4e-16 60.0 7.3 1.7 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 AAZ33863.1 - 1.7e-29 103.0 0.0 2.9e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAZ33863.1 - 3.4e-08 33.6 0.4 0.00089 19.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 AAZ33863.1 - 0.00051 20.0 0.1 0.00094 19.1 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 AAZ33863.1 - 0.0019 18.6 1.4 0.0089 16.4 1.4 1.9 1 1 0 1 1 1 1 AAA ATPase domain ABC_ATPase PF09818.9 AAZ33863.1 - 0.0079 15.0 0.6 0.054 12.3 0.0 2.0 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_29 PF13555.6 AAZ33863.1 - 0.0089 15.8 0.1 0.02 14.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 AAZ33863.1 - 0.12 11.8 0.7 0.71 9.3 0.7 2.0 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain CBS PF00571.28 AAZ33863.1 - 0.13 12.7 0.0 0.47 11.0 0.0 2.0 1 0 0 1 1 1 0 CBS domain Cuticle_1 PF08140.11 AAZ33863.1 - 0.13 12.3 0.5 0.51 10.4 0.0 2.2 3 0 0 3 3 3 0 Crustacean cuticle protein repeat AAA_23 PF13476.6 AAZ33863.1 - 0.21 12.0 0.1 0.39 11.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain Acetyltransf_3 PF13302.7 AAZ33864.1 - 9.7e-29 100.8 0.0 1.3e-28 100.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAZ33864.1 - 6.3e-05 23.2 0.0 8.1e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family EAL PF00563.20 AAZ33865.1 - 1.1e-65 221.5 0.0 1.8e-65 220.8 0.0 1.4 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AAZ33865.1 - 1e-37 129.4 0.0 2e-37 128.4 0.0 1.5 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS PF00989.25 AAZ33865.1 - 5.5e-12 45.7 0.0 2e-11 43.9 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 AAZ33865.1 - 2.6e-11 43.7 0.0 1.4e-10 41.4 0.0 2.3 3 0 0 3 3 3 1 PAS fold PAS_9 PF13426.7 AAZ33865.1 - 2e-10 40.9 0.0 4.7e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 PAS domain GAF PF01590.26 AAZ33865.1 - 6.5e-08 33.3 0.1 2.4e-07 31.5 0.1 1.9 2 0 0 2 2 2 1 GAF domain PAS_8 PF13188.7 AAZ33865.1 - 3.9e-07 29.9 0.0 0.00018 21.4 0.0 2.7 2 0 0 2 2 2 1 PAS domain GAF_3 PF13492.6 AAZ33865.1 - 0.0011 19.4 0.1 0.008 16.5 0.0 2.5 2 1 0 2 2 2 1 GAF domain PAS_3 PF08447.12 AAZ33865.1 - 0.0062 16.8 0.0 0.015 15.5 0.0 1.7 1 0 0 1 1 1 1 PAS fold sCache_3_3 PF17202.4 AAZ33865.1 - 0.17 12.3 0.0 2.3 8.7 0.0 2.2 2 0 0 2 2 2 0 Single cache domain 3 MreD PF04093.12 AAZ33866.1 - 1.8e-34 119.1 16.8 2.5e-34 118.7 16.8 1.0 1 0 0 1 1 1 1 rod shape-determining protein MreD ZnuA PF01297.17 AAZ33867.1 - 2.7e-79 266.2 0.0 3.1e-79 266.0 0.0 1.0 1 0 0 1 1 1 1 Zinc-uptake complex component A periplasmic DUF1652 PF07865.11 AAZ33867.1 - 0.17 11.7 0.0 0.43 10.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1652) BPD_transp_1 PF00528.22 AAZ33868.1 - 1.6e-25 89.9 11.7 1.6e-25 89.9 11.7 2.2 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Trp_oprn_chp PF09534.10 AAZ33868.1 - 0.0096 15.7 0.1 0.0096 15.7 0.1 2.6 2 1 0 2 2 2 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF3464 PF11947.8 AAZ33868.1 - 0.081 12.7 3.1 0.15 11.8 3.1 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF3671 PF12420.8 AAZ33868.1 - 2.7 8.1 5.1 3 8.0 2.6 2.1 2 1 0 2 2 2 0 Protein of unknown function FtsX PF02687.21 AAZ33868.1 - 5.3 7.6 26.8 0.76 10.3 0.9 3.5 2 1 1 3 3 3 0 FtsX-like permease family HATPase_c PF02518.26 AAZ33869.1 - 6.5e-24 84.6 0.0 1.1e-23 83.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AAZ33869.1 - 3.6e-21 75.4 0.0 8.2e-21 74.3 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 AAZ33869.1 - 3.1e-10 39.9 1.0 3.1e-10 39.9 1.0 2.8 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 AAZ33869.1 - 1.6e-05 24.9 0.0 3.1e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 AAZ33869.1 - 0.0021 17.9 0.0 0.0043 16.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF945 PF06097.11 AAZ33869.1 - 0.022 13.9 0.1 0.039 13.1 0.1 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) Uds1 PF15456.6 AAZ33869.1 - 0.035 14.3 3.4 0.076 13.2 3.4 1.6 1 0 0 1 1 1 0 Up-regulated During Septation HATPase_c_5 PF14501.6 AAZ33869.1 - 0.075 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 GHKL domain DUF3557 PF12078.8 AAZ33869.1 - 0.077 12.9 1.0 0.14 12.1 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3557) MCD_N PF17408.2 AAZ33869.1 - 0.25 11.5 3.9 0.27 11.4 1.9 2.1 1 1 1 2 2 2 0 Malonyl-CoA decarboxylase N-terminal domain DivIC PF04977.15 AAZ33869.1 - 2.6 7.9 5.4 0.83 9.5 1.2 2.4 3 0 0 3 3 3 0 Septum formation initiator Spc29 PF17082.5 AAZ33869.1 - 5.2 6.8 7.0 1 9.2 2.3 1.9 1 1 1 2 2 2 0 Spindle Pole Component 29 PEP-utilizers_C PF02896.18 AAZ33870.1 - 6.4e-99 330.8 0.0 1.1e-98 330.0 0.0 1.4 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilisers_N PF05524.13 AAZ33870.1 - 9.1e-26 90.3 0.1 2.2e-25 89.1 0.1 1.7 1 0 0 1 1 1 1 PEP-utilising enzyme, N-terminal PEP-utilizers PF00391.23 AAZ33870.1 - 9.2e-17 60.5 0.1 2.1e-16 59.4 0.1 1.7 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain GAF PF01590.26 AAZ33870.1 - 4.3e-15 56.5 0.0 2.9e-14 53.8 0.0 2.4 2 0 0 2 2 2 1 GAF domain GAF_2 PF13185.6 AAZ33870.1 - 2.8e-14 53.6 0.1 1e-13 51.8 0.1 2.1 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 AAZ33870.1 - 2.6e-13 50.4 0.0 6.2e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 GAF domain HpcH_HpaI PF03328.14 AAZ33870.1 - 0.013 14.6 0.0 0.028 13.6 0.0 1.5 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family Sec8_exocyst PF04048.14 AAZ33870.1 - 0.058 13.3 0.0 0.19 11.6 0.0 1.9 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain SpoVT_C PF15714.5 AAZ33870.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Stage V sporulation protein T C-terminal, transcription factor MTS PF05175.14 AAZ33871.1 - 5.2e-55 185.6 0.0 7.9e-55 185.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain MTS_N PF08468.11 AAZ33871.1 - 7.7e-41 139.8 0.0 3.2e-40 137.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain N-terminal Methyltransf_25 PF13649.6 AAZ33871.1 - 7.4e-08 33.0 0.0 1.5e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 AAZ33871.1 - 3.8e-06 26.3 0.0 5.6e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 AAZ33871.1 - 1.5e-05 25.6 0.0 4.4e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAZ33871.1 - 1.6e-05 24.8 0.0 2.5e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 AAZ33871.1 - 1.7e-05 24.4 0.1 2.5e-05 23.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 AAZ33871.1 - 0.00086 19.2 0.0 0.0064 16.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 AAZ33871.1 - 0.0042 16.8 0.0 0.0065 16.2 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_11 PF08241.12 AAZ33871.1 - 0.006 17.2 0.1 0.025 15.2 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 AAZ33871.1 - 0.076 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TauD PF02668.16 AAZ33872.1 - 1.4e-50 172.6 0.0 1.6e-50 172.4 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family FlaE PF07559.14 AAZ33873.1 - 1.4e-27 96.6 3.3 3.1e-18 66.5 0.2 3.3 3 1 0 3 3 3 2 Flagellar basal body protein FlaE Flg_bbr_C PF06429.13 AAZ33873.1 - 1.1e-11 44.7 3.3 1.1e-11 44.7 0.5 2.5 2 0 0 2 2 2 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 AAZ33873.1 - 2.2e-06 27.5 0.9 2.2e-06 27.5 0.9 2.2 2 0 0 2 2 2 1 Flagella basal body rod protein Response_reg PF00072.24 AAZ33874.1 - 1.2e-20 73.7 0.0 1.9e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AAZ33874.1 - 6.9e-17 60.7 0.1 1.1e-16 60.1 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_28 PF13518.6 AAZ33874.1 - 4e-07 30.1 0.5 0.0032 17.6 0.1 2.5 2 1 0 2 2 2 2 Helix-turn-helix domain HTH_29 PF13551.6 AAZ33874.1 - 7.3e-06 25.9 0.4 0.0018 18.2 0.1 2.5 1 1 1 2 2 2 1 Winged helix-turn helix Sigma70_r4 PF04545.16 AAZ33874.1 - 1.9e-05 24.1 0.2 4.8e-05 22.8 0.2 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 AAZ33874.1 - 2.2e-05 24.1 0.4 0.00032 20.4 0.1 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.6 AAZ33874.1 - 8.2e-05 22.3 0.0 0.00017 21.2 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_7 PF02796.15 AAZ33874.1 - 0.00016 21.6 0.0 0.00037 20.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_20 PF12840.7 AAZ33874.1 - 0.00072 19.6 0.1 0.0018 18.3 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 AAZ33874.1 - 0.00099 18.9 0.1 0.0029 17.4 0.1 1.8 1 0 0 1 1 1 1 MarR family Sigma70_r4_2 PF08281.12 AAZ33874.1 - 0.006 16.2 0.4 0.011 15.4 0.4 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_11 PF08279.12 AAZ33874.1 - 0.047 13.6 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 HTH domain HTH_5 PF01022.20 AAZ33874.1 - 0.047 13.5 0.1 0.11 12.4 0.1 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_40 PF14493.6 AAZ33874.1 - 0.13 12.7 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain STAS_2 PF13466.6 AAZ33875.1 - 2.8e-17 62.8 0.1 3.5e-17 62.5 0.1 1.1 1 0 0 1 1 1 1 STAS domain STAS PF01740.21 AAZ33875.1 - 2.8e-08 33.4 0.0 3.5e-08 33.1 0.0 1.0 1 0 0 1 1 1 1 STAS domain Egh16-like PF11327.8 AAZ33875.1 - 0.043 14.2 0.1 0.05 14.0 0.1 1.1 1 0 0 1 1 1 0 Egh16-like virulence factor Response_reg PF00072.24 AAZ33876.1 - 1.4e-30 105.8 0.1 1.9e-30 105.3 0.1 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAZ33876.1 - 4.4e-25 87.6 0.1 7.7e-25 86.8 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal ABC_tran PF00005.27 AAZ33877.1 - 6.3e-35 120.7 0.0 1.7e-34 119.3 0.0 1.7 2 0 0 2 2 2 1 ABC transporter CBS PF00571.28 AAZ33877.1 - 3.3e-11 43.5 0.0 1.1e-06 28.9 0.0 2.8 2 0 0 2 2 2 2 CBS domain AAA_21 PF13304.6 AAZ33877.1 - 4.8e-06 26.6 0.1 0.0036 17.2 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 AAZ33877.1 - 0.00057 19.9 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_29 PF13555.6 AAZ33877.1 - 0.00087 19.0 0.0 0.002 17.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AAZ33877.1 - 0.00097 19.6 0.0 0.0024 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AAZ33877.1 - 0.001 19.0 0.1 0.0021 18.0 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_5 PF07728.14 AAZ33877.1 - 0.017 15.1 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) G-alpha PF00503.20 AAZ33877.1 - 0.019 14.2 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_30 PF13604.6 AAZ33877.1 - 0.028 14.1 0.0 0.064 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 AAZ33877.1 - 0.06 13.8 0.0 0.27 11.6 0.0 2.1 3 0 0 3 3 2 0 RNA helicase AAA_22 PF13401.6 AAZ33877.1 - 0.068 13.4 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 AAZ33877.1 - 0.068 13.2 0.0 0.22 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 AAZ33877.1 - 0.13 12.0 0.1 0.2 11.3 0.1 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.7 AAZ33877.1 - 0.14 11.0 0.0 0.93 8.3 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain MdoG PF04349.12 AAZ33878.1 - 7.9e-188 625.2 0.1 1.4e-187 624.4 0.0 1.4 2 0 0 2 2 2 1 Periplasmic glucan biosynthesis protein, MdoG Oxidored_q2 PF00420.24 AAZ33880.1 - 3.3e-24 84.5 5.6 3.8e-24 84.3 5.6 1.0 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L ATP1G1_PLM_MAT8 PF02038.16 AAZ33880.1 - 0.067 12.6 0.4 0.067 12.6 0.4 1.8 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family NAD4L PF06235.11 AAZ33880.1 - 0.069 13.1 7.2 0.36 10.9 7.2 2.0 1 1 0 1 1 1 0 NADH dehydrogenase subunit 4L (NAD4L) PP-binding PF00550.25 AAZ33881.1 - 0.0034 17.7 0.1 0.0038 17.5 0.1 1.2 1 1 0 1 1 1 1 Phosphopantetheine attachment site BPD_transp_1 PF00528.22 AAZ33882.1 - 3e-21 76.0 12.6 3.8e-21 75.7 12.6 1.2 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component DUF1516 PF07457.11 AAZ33882.1 - 0.082 13.1 0.2 0.082 13.1 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1516) PBP_like_2 PF12849.7 AAZ33883.1 - 3.4e-29 102.4 0.2 7.5e-29 101.3 0.2 1.5 1 1 0 1 1 1 1 PBP superfamily domain OmpA PF00691.20 AAZ33883.1 - 7.1e-16 58.4 1.6 9.2e-16 58.0 0.0 2.0 2 0 0 2 2 2 1 OmpA family PBP_like PF12727.7 AAZ33883.1 - 3e-15 55.8 0.0 6.7e-15 54.7 0.0 1.6 1 0 0 1 1 1 1 PBP superfamily domain SBP_bac_11 PF13531.6 AAZ33883.1 - 0.0001 22.1 1.0 0.0001 22.1 1.0 2.8 2 1 0 2 2 2 1 Bacterial extracellular solute-binding protein Phage_X PF05155.15 AAZ33883.1 - 0.18 12.2 0.0 0.45 11.0 0.0 1.6 1 0 0 1 1 1 0 Phage X family CDP-OH_P_transf PF01066.21 AAZ33884.1 - 1.3e-18 67.5 0.6 1.3e-18 67.5 0.6 2.6 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF1418 PF07214.12 AAZ33884.1 - 1.6 8.6 6.0 1.3 8.9 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1418) Ribosomal_L36 PF00444.18 AAZ33885.1 - 6.2e-21 74.3 8.8 6.6e-21 74.2 8.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L36 Ring_hydroxyl_A PF00848.19 AAZ33886.1 - 7.7e-45 153.5 1.3 1.3e-44 152.8 1.3 1.3 1 0 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 AAZ33886.1 - 5.5e-16 58.3 0.1 1e-15 57.4 0.1 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain FCD PF07729.12 AAZ33887.1 - 4e-23 82.2 14.8 4e-23 82.2 14.8 2.0 3 0 0 3 3 3 1 FCD domain GntR PF00392.21 AAZ33887.1 - 9.4e-22 76.4 1.0 9.4e-22 76.4 1.0 2.0 3 0 0 3 3 3 1 Bacterial regulatory proteins, gntR family Rrf2 PF02082.20 AAZ33887.1 - 4.5e-05 23.7 0.1 0.00027 21.2 0.0 2.2 2 0 0 2 2 2 1 Transcriptional regulator MarR_2 PF12802.7 AAZ33887.1 - 0.0041 17.0 0.1 0.0041 17.0 0.1 2.8 3 0 0 3 3 3 1 MarR family PaaX PF07848.12 AAZ33887.1 - 0.0041 17.3 0.1 0.0094 16.2 0.1 1.6 1 0 0 1 1 1 1 PaaX-like protein HTH_41 PF14502.6 AAZ33887.1 - 0.005 16.5 0.1 0.01 15.5 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_11 PF08279.12 AAZ33887.1 - 0.0052 16.7 0.1 0.013 15.4 0.1 1.6 1 0 0 1 1 1 1 HTH domain TrmB PF01978.19 AAZ33887.1 - 0.011 15.6 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_CodY PF08222.11 AAZ33887.1 - 0.017 14.6 0.3 0.038 13.5 0.1 1.6 2 0 0 2 2 2 0 CodY helix-turn-helix domain HTH_5 PF01022.20 AAZ33887.1 - 0.039 13.8 0.0 15 5.6 0.0 2.6 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 AAZ33887.1 - 0.052 13.1 0.1 0.13 11.8 0.1 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding EAP30 PF04157.16 AAZ33887.1 - 0.54 9.5 4.1 1.6 7.9 0.1 2.3 2 1 0 2 2 2 0 EAP30/Vps36 family adh_short PF00106.25 AAZ33888.1 - 3.3e-40 137.6 0.0 4.6e-40 137.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAZ33888.1 - 2.5e-33 115.6 0.0 3.1e-33 115.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAZ33888.1 - 2.4e-07 30.9 0.1 3.6e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 AAZ33888.1 - 4.6e-06 26.6 0.1 1.1e-05 25.5 0.1 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 AAZ33888.1 - 0.017 14.6 0.1 0.026 14.0 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 AAZ33888.1 - 0.03 13.7 0.0 0.28 10.5 0.0 1.9 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) RNA_pol_Rpb2_5 PF04567.17 AAZ33888.1 - 0.16 12.5 0.0 0.28 11.8 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 5 DUF1127 PF06568.11 AAZ33889.1 - 4.7e-09 35.8 3.5 6e-09 35.5 3.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1127) DUF1826 PF08856.11 AAZ33890.1 - 1.4e-66 224.3 0.0 1.5e-66 224.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1826) 2-Hacid_dh_C PF02826.19 AAZ33891.1 - 1.2e-56 190.9 0.0 1.8e-56 190.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 AAZ33891.1 - 1.1e-10 41.3 0.0 1.3e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 AAZ33891.1 - 0.00052 20.2 0.0 0.00089 19.5 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 AAZ33891.1 - 0.014 14.9 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 AAZ33891.1 - 0.14 12.7 0.0 0.28 11.8 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AICARFT_IMPCHas PF01808.18 AAZ33892.1 - 4.5e-116 387.4 4.2 5.6e-116 387.1 4.2 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 AAZ33892.1 - 6.6e-27 93.5 0.0 2.1e-26 91.9 0.0 1.9 1 0 0 1 1 1 1 MGS-like domain Fe-S_assembly PF04384.13 AAZ33893.1 - 9.6e-28 96.6 0.1 1e-27 96.5 0.1 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster assembly OST-HTH PF12872.7 AAZ33893.1 - 0.14 11.9 0.0 0.23 11.3 0.0 1.4 1 1 0 1 1 1 0 OST-HTH/LOTUS domain PhzC-PhzF PF02567.16 AAZ33894.1 - 4.4e-46 157.6 0.0 4.9e-46 157.4 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Peripla_BP_6 PF13458.6 AAZ33895.1 - 5.7e-67 226.8 7.7 6.9e-67 226.5 7.7 1.0 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 AAZ33895.1 - 3.9e-30 105.2 0.0 4.9e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_5 PF13433.6 AAZ33895.1 - 3.9e-27 95.2 0.4 6.1e-27 94.6 0.4 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain Fe-ADH PF00465.19 AAZ33895.1 - 0.011 14.6 0.1 0.011 14.6 0.1 1.7 2 0 0 2 2 2 0 Iron-containing alcohol dehydrogenase PGM_PMM_I PF02878.16 AAZ33895.1 - 0.022 14.5 0.5 0.27 11.0 0.1 2.5 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I AAA_PrkA PF08298.11 AAZ33896.1 - 1e-179 597.0 0.0 1.3e-179 596.6 0.0 1.1 1 0 0 1 1 1 1 PrkA AAA domain PrkA PF06798.12 AAZ33896.1 - 6.3e-73 245.6 2.0 1.1e-72 244.7 2.0 1.4 1 0 0 1 1 1 1 PrkA serine protein kinase C-terminal domain AAA_16 PF13191.6 AAZ33896.1 - 0.0018 18.7 0.0 0.0073 16.7 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 AAZ33896.1 - 0.0031 17.8 0.1 0.032 14.5 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 AAZ33896.1 - 0.011 15.7 0.1 0.088 12.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) FolB PF02152.18 AAZ33897.1 - 1.2e-26 93.4 2.2 1.4e-26 93.2 2.2 1.0 1 0 0 1 1 1 1 Dihydroneopterin aldolase Pro_isomerase PF00160.21 AAZ33899.1 - 1.3e-44 152.3 0.7 1.4e-44 152.1 0.7 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DHquinase_II PF01220.19 AAZ33900.1 - 2.1e-60 202.3 0.0 2.4e-60 202.2 0.0 1.0 1 0 0 1 1 1 1 Dehydroquinase class II DapB_N PF01113.20 AAZ33901.1 - 3.4e-44 149.9 0.5 5.2e-43 146.1 0.0 2.2 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus DapB_C PF05173.14 AAZ33901.1 - 3e-43 146.7 0.0 4.2e-43 146.2 0.0 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, C-terminus Semialdhyde_dh PF01118.24 AAZ33901.1 - 0.0094 16.4 1.3 0.08 13.4 0.2 2.6 2 1 1 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain ABC_sub_bind PF04392.12 AAZ33901.1 - 0.12 11.6 0.1 0.27 10.4 0.0 1.6 2 0 0 2 2 2 0 ABC transporter substrate binding protein Sacchrp_dh_NADP PF03435.18 AAZ33901.1 - 0.17 12.1 0.6 1.1 9.5 0.2 2.3 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DNA_pol3_chi PF04364.13 AAZ33902.1 - 2.1e-37 128.3 0.0 2.3e-37 128.2 0.0 1.0 1 0 0 1 1 1 1 DNA polymerase III chi subunit, HolC Peripla_BP_6 PF13458.6 AAZ33903.1 - 3.4e-17 63.1 0.2 9e-16 58.5 0.1 2.2 2 0 0 2 2 2 2 Periplasmic binding protein ANF_receptor PF01094.28 AAZ33903.1 - 3.8e-08 32.8 0.0 1.2e-07 31.1 0.0 1.6 2 0 0 2 2 2 1 Receptor family ligand binding region DUF2914 PF11141.8 AAZ33904.1 - 2.4e-23 81.7 1.9 4e-23 80.9 1.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2914) P5-ATPase PF12409.8 AAZ33904.1 - 0.22 11.6 1.1 0.45 10.6 1.1 1.5 1 0 0 1 1 1 0 P5-type ATPase cation transporter Tmemb_18A PF09771.9 AAZ33904.1 - 0.25 11.7 0.9 2.7 8.4 0.1 2.4 2 0 0 2 2 2 0 Transmembrane protein 188 Glyco_hydro_77 PF02446.17 AAZ33906.1 - 9e-114 380.9 0.0 1.1e-113 380.5 0.0 1.0 1 0 0 1 1 1 1 4-alpha-glucanotransferase Tannase PF07519.11 AAZ33907.1 - 4.7e-164 546.7 0.0 6.2e-164 546.3 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 AAZ33907.1 - 0.00013 21.6 0.0 0.061 12.8 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 AAZ33907.1 - 0.12 11.6 0.0 0.28 10.4 0.0 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 BPD_transp_1 PF00528.22 AAZ33908.1 - 3.7e-25 88.8 12.3 3.7e-25 88.8 12.3 2.3 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component 4HBT PF03061.22 AAZ33909.1 - 2.8e-18 66.0 0.6 4.3e-18 65.4 0.6 1.2 1 0 0 1 1 1 1 Thioesterase superfamily NAD_binding_10 PF13460.6 AAZ33910.1 - 1.7e-08 34.6 0.0 2e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 AAZ33910.1 - 0.00025 20.3 0.0 0.19 10.8 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein Epimerase PF01370.21 AAZ33910.1 - 0.00057 19.4 0.0 0.0015 18.1 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 AAZ33910.1 - 0.00078 19.9 0.0 0.0017 18.8 0.0 1.7 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Abhydrolase_2 PF02230.16 AAZ33911.1 - 5.7e-26 91.7 0.0 7.8e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.18 AAZ33911.1 - 4.6e-07 29.6 0.0 6.4e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 AAZ33911.1 - 1.2e-05 24.8 0.1 0.021 14.1 0.1 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AAZ33911.1 - 2.3e-05 25.1 0.0 0.00014 22.5 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AAZ33911.1 - 5.9e-05 22.8 0.2 0.00034 20.3 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 AAZ33911.1 - 7.2e-05 22.4 0.1 0.05 13.1 0.0 2.2 1 1 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.20 AAZ33911.1 - 0.00076 19.2 0.0 0.0017 18.1 0.0 1.5 1 1 0 1 1 1 1 Putative esterase FSH1 PF03959.13 AAZ33911.1 - 0.0025 17.5 0.0 0.0094 15.6 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DUF676 PF05057.14 AAZ33911.1 - 0.0027 17.2 0.0 0.089 12.3 0.0 2.6 1 1 1 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_3 PF07859.13 AAZ33911.1 - 0.0049 16.8 0.0 0.0078 16.1 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.9 AAZ33911.1 - 0.019 14.5 0.0 0.035 13.6 0.0 1.5 1 1 0 1 1 1 0 Esterase PHB depolymerase Abhydrolase_8 PF06259.12 AAZ33911.1 - 0.074 12.7 0.0 9.6 5.8 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase DAO PF01266.24 AAZ33913.1 - 3.8e-52 178.0 2.9 4.4e-52 177.8 2.9 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AAZ33913.1 - 1.1e-06 28.8 2.7 2.2e-06 27.8 1.8 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AAZ33913.1 - 1.1e-05 24.9 0.3 4.4e-05 22.9 0.3 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AAZ33913.1 - 1.5e-05 24.3 1.2 2.7e-05 23.4 1.2 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 AAZ33913.1 - 3.2e-05 23.5 0.1 4.6e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 AAZ33913.1 - 3.3e-05 23.2 1.7 5.5e-05 22.5 1.7 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 AAZ33913.1 - 0.00014 21.3 0.5 0.00014 21.3 0.5 1.6 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 AAZ33913.1 - 0.00058 19.1 0.4 0.0016 17.6 1.0 1.4 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 AAZ33913.1 - 0.0006 18.6 0.5 0.0015 17.4 0.2 1.6 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 AAZ33913.1 - 0.0018 17.6 0.0 0.034 13.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAZ33913.1 - 0.0025 18.3 1.2 0.0073 16.8 0.4 2.2 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 AAZ33913.1 - 0.01 15.1 0.3 0.34 10.1 0.2 2.4 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 AAZ33913.1 - 0.041 12.9 0.2 0.061 12.4 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.14 AAZ33913.1 - 0.15 11.7 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_9 PF13454.6 AAZ33913.1 - 2.6 8.0 5.0 0.58 10.1 0.4 2.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding Sulfatase PF00884.23 AAZ33914.1 - 2.2e-52 178.4 0.0 3.3e-52 177.8 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.8 AAZ33914.1 - 1.1e-26 92.4 1.3 2.1e-26 91.5 1.3 1.5 1 0 0 1 1 1 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.22 AAZ33914.1 - 6.7e-09 35.8 0.0 0.0026 17.4 0.0 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 AAZ33914.1 - 0.00015 22.0 0.0 0.00032 20.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) Sulfatase_C PF14707.6 AAZ33914.1 - 0.00076 20.2 1.8 0.0014 19.4 0.1 2.1 2 1 1 3 3 3 1 C-terminal region of aryl-sulfatase DUF229 PF02995.17 AAZ33914.1 - 0.065 11.8 0.0 0.085 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DUF1501 PF07394.12 AAZ33914.1 - 0.09 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Transketolase_N PF00456.21 AAZ33915.1 - 4e-39 134.5 0.1 7.3e-39 133.6 0.1 1.3 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain E1_dh PF00676.20 AAZ33915.1 - 2.6e-07 29.9 0.0 3.4e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 AAZ33915.1 - 0.00065 19.0 0.1 0.089 12.0 0.1 2.9 2 1 1 3 3 3 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 AAZ33915.1 - 0.045 13.5 0.1 0.21 11.4 0.1 2.0 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain XFP_N PF09364.10 AAZ33915.1 - 0.059 12.2 0.1 0.12 11.1 0.0 1.5 2 0 0 2 2 2 0 XFP N-terminal domain DUF5053 PF16476.5 AAZ33915.1 - 0.15 11.8 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5053) adh_short_C2 PF13561.6 AAZ33916.1 - 6.3e-57 192.8 0.3 7.2e-57 192.6 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAZ33916.1 - 2e-46 157.9 0.2 2.5e-46 157.6 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAZ33916.1 - 1.6e-15 57.5 0.4 2.3e-15 57.0 0.4 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AAZ33916.1 - 1.3e-05 24.8 0.0 2e-05 24.2 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 AAZ33916.1 - 0.0013 18.1 0.0 0.0035 16.7 0.0 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Polysacc_synt_2 PF02719.15 AAZ33916.1 - 0.0071 15.5 0.0 0.0097 15.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ApbA PF02558.16 AAZ33916.1 - 0.0087 15.7 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 AAZ33916.1 - 0.025 14.5 0.1 0.08 12.8 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 AAZ33916.1 - 0.041 13.8 0.1 0.1 12.5 0.1 1.6 2 0 0 2 2 2 0 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 AAZ33916.1 - 0.055 13.7 0.0 0.14 12.4 0.0 1.8 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 AAZ33916.1 - 0.056 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase CoA_binding_2 PF13380.6 AAZ33916.1 - 0.063 13.8 0.1 1.2 9.7 0.0 2.3 2 1 0 2 2 2 0 CoA binding domain Glyco_transf_4 PF13439.6 AAZ33916.1 - 0.086 12.8 0.1 13 5.7 0.0 2.2 2 0 0 2 2 2 0 Glycosyltransferase Family 4 NmrA PF05368.13 AAZ33916.1 - 0.15 11.6 0.2 3.1 7.3 0.1 2.1 2 0 0 2 2 2 0 NmrA-like family Orn_Arg_deC_N PF02784.16 AAZ33916.1 - 0.17 11.2 0.1 0.17 11.2 0.1 1.4 2 0 0 2 2 2 0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain FCD PF07729.12 AAZ33917.1 - 3.4e-27 95.4 8.0 5.5e-27 94.7 8.0 1.4 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 AAZ33917.1 - 6e-20 70.7 1.4 7.1e-20 70.4 0.2 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family Rrf2 PF02082.20 AAZ33917.1 - 0.00067 20.0 0.1 0.0017 18.6 0.1 1.7 1 0 0 1 1 1 1 Transcriptional regulator MarR_2 PF12802.7 AAZ33917.1 - 0.0018 18.1 2.8 0.0048 16.7 0.2 2.8 2 1 0 3 3 3 1 MarR family HTH_20 PF12840.7 AAZ33917.1 - 0.012 15.6 0.3 1.6 8.9 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_11 PF08279.12 AAZ33917.1 - 0.04 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 HTH domain Fe_dep_repress PF01325.19 AAZ33917.1 - 0.092 13.0 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_41 PF14502.6 AAZ33917.1 - 0.12 12.1 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain AstE_AspA PF04952.14 AAZ33918.1 - 2.4e-74 250.0 0.0 2.8e-74 249.8 0.0 1.0 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Complex1_51K PF01512.17 AAZ33919.1 - 2.8e-51 173.4 0.0 3.9e-51 172.9 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 AAZ33919.1 - 1.5e-23 82.7 0.0 2.5e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 AAZ33919.1 - 0.00043 20.1 0.0 0.001 18.9 0.0 1.6 1 0 0 1 1 1 1 SLBB domain DUF2339 PF10101.9 AAZ33920.1 - 1e-163 546.5 124.9 2.9e-163 545.0 124.9 1.6 1 1 0 1 1 1 1 Predicted membrane protein (DUF2339) SLATT_1 PF18181.1 AAZ33920.1 - 0.011 15.7 1.5 0.011 15.7 1.5 5.1 3 3 3 6 6 6 0 SMODS and SLOG-associating 2TM effector domain 1 DUF3810 PF12725.7 AAZ33920.1 - 2.2 7.5 3.3 2 7.7 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Kdo PF06293.14 AAZ33923.1 - 1.4e-51 174.8 0.2 1.6e-51 174.7 0.2 1.0 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family BPD_transp_1 PF00528.22 AAZ33924.1 - 2.6e-34 118.6 11.9 2.6e-34 118.6 11.9 2.0 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component MTHFR PF02219.17 AAZ33925.1 - 2.3e-89 299.5 0.0 2.8e-89 299.2 0.0 1.0 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Response_reg PF00072.24 AAZ33926.1 - 1.4e-27 96.1 0.1 1.5e-27 96.0 0.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain TonB_C PF03544.14 AAZ33927.1 - 0.00037 20.9 0.0 0.00068 20.0 0.0 1.4 1 0 0 1 1 1 1 Gram-negative bacterial TonB protein C-terminal GAD-like PF08887.11 AAZ33928.1 - 9.3e-35 118.7 0.2 1.3e-34 118.1 0.2 1.2 1 0 0 1 1 1 1 GAD-like domain DUF1851 PF08906.11 AAZ33928.1 - 3.2e-22 78.3 0.1 5.3e-22 77.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1851) Thiolase_N PF00108.23 AAZ33929.1 - 3.3e-104 347.8 4.5 4.3e-104 347.5 4.5 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 AAZ33929.1 - 3.7e-51 171.9 0.5 7.9e-51 170.8 0.5 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 AAZ33929.1 - 6.7e-07 29.1 1.3 6.7e-07 29.1 1.3 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 AAZ33929.1 - 0.0098 15.7 2.2 0.18 11.7 0.2 2.7 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.10 AAZ33929.1 - 0.072 13.3 0.1 0.22 11.7 0.1 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ABC_tran PF00005.27 AAZ33930.1 - 9.5e-37 126.6 0.0 1.6e-36 125.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAZ33930.1 - 2.4e-10 40.7 1.0 5.9e-05 23.0 0.2 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system TOBE_2 PF08402.10 AAZ33930.1 - 4.2e-08 33.2 0.1 9.7e-08 32.1 0.1 1.7 1 0 0 1 1 1 1 TOBE domain SMC_N PF02463.19 AAZ33930.1 - 0.00011 21.8 0.5 0.096 12.1 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AAZ33930.1 - 0.00036 21.0 1.5 0.0041 17.5 1.5 2.4 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AAZ33930.1 - 0.00089 19.2 0.1 0.0025 17.7 0.1 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 AAZ33930.1 - 0.0028 17.9 1.0 0.018 15.3 1.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAZ33930.1 - 0.0044 16.7 0.1 0.0097 15.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 AAZ33930.1 - 0.0052 16.4 0.1 0.11 12.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 AAZ33930.1 - 0.015 15.7 0.1 0.041 14.3 0.1 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 AAZ33930.1 - 0.015 15.8 0.8 0.026 15.0 0.1 1.7 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 AAZ33930.1 - 0.023 13.5 0.0 0.89 8.3 0.0 2.7 2 1 0 2 2 2 0 Predicted ATPase of the ABC class AAA_5 PF07728.14 AAZ33930.1 - 0.038 14.0 0.1 0.12 12.4 0.1 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 AAZ33930.1 - 0.039 13.3 0.1 0.14 11.5 0.0 1.8 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI sCache_3_2 PF17203.4 AAZ33930.1 - 0.06 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Single cache domain 3 Rad17 PF03215.15 AAZ33930.1 - 0.068 13.1 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain NACHT PF05729.12 AAZ33930.1 - 0.069 13.1 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 NACHT domain ATPase PF06745.13 AAZ33930.1 - 0.075 12.4 0.3 3.4 6.9 0.1 2.2 2 0 0 2 2 2 0 KaiC NB-ARC PF00931.22 AAZ33930.1 - 0.079 12.1 0.0 0.18 10.9 0.0 1.6 1 1 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.6 AAZ33930.1 - 0.084 13.0 0.5 0.4 10.8 0.5 2.1 1 1 0 1 1 1 0 AAA domain Urease_gamma PF00547.18 AAZ33931.1 - 1.5e-46 156.8 0.1 1.6e-46 156.6 0.1 1.0 1 0 0 1 1 1 1 Urease, gamma subunit Flavodoxin_1 PF00258.25 AAZ33932.1 - 2e-15 57.2 0.0 2.4e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_NdrI PF07972.11 AAZ33932.1 - 0.093 12.9 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 NrdI Flavodoxin like LysR_substrate PF03466.20 AAZ33933.1 - 4.5e-38 130.7 4.0 4.5e-38 130.7 4.0 1.7 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ33933.1 - 4.4e-14 52.2 1.0 8.4e-14 51.3 1.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family BCCT PF02028.17 AAZ33934.1 - 4.8e-176 586.0 37.7 5.6e-176 585.7 37.7 1.0 1 0 0 1 1 1 1 BCCT, betaine/carnitine/choline family transporter TetR_N PF00440.23 AAZ33935.1 - 4.6e-09 35.9 0.0 8.4e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family LysR_substrate PF03466.20 AAZ33936.1 - 4.4e-16 58.9 5.2 6.9e-16 58.2 5.2 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ33936.1 - 1.9e-13 50.2 1.8 2.7e-13 49.6 0.2 2.1 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_AsnC-type PF13404.6 AAZ33936.1 - 0.00025 20.8 0.1 0.0021 17.8 0.1 2.4 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 AAZ33936.1 - 0.03 13.9 0.1 0.09 12.4 0.1 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 AAZ33936.1 - 0.055 13.6 0.1 0.18 12.0 0.1 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_20 PF12840.7 AAZ33936.1 - 0.065 13.3 0.7 0.41 10.7 0.0 2.7 3 1 1 4 4 4 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 AAZ33936.1 - 0.078 12.5 0.1 0.22 11.1 0.1 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 MarR_2 PF12802.7 AAZ33936.1 - 0.092 12.6 0.3 0.092 12.6 0.3 4.0 5 0 0 5 5 5 0 MarR family P22_Cro PF14549.6 AAZ33936.1 - 0.14 12.0 0.1 0.25 11.2 0.1 1.3 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro HTH_3 PF01381.22 AAZ33937.1 - 0.00036 20.5 0.1 0.00076 19.5 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 AAZ33937.1 - 0.0067 16.7 0.1 0.012 16.0 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain MqsA_antitoxin PF15731.5 AAZ33937.1 - 0.031 14.4 0.0 0.058 13.5 0.0 1.4 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA AA_kinase PF00696.28 AAZ33938.1 - 2.8e-27 95.9 0.6 3.5e-27 95.5 0.6 1.1 1 0 0 1 1 1 1 Amino acid kinase family DUF2126 PF09899.9 AAZ33939.1 - 0 1351.6 0.0 0 1351.4 0.0 1.0 1 0 0 1 1 1 1 Putative amidoligase enzyme (DUF2126) Bact_transglu_N PF08379.10 AAZ33939.1 - 1.2e-27 96.6 1.1 2.6e-27 95.5 1.1 1.6 1 0 0 1 1 1 1 Bacterial transglutaminase-like N-terminal region Transglut_core PF01841.19 AAZ33939.1 - 1.2e-17 64.4 0.0 3.9e-17 62.7 0.0 1.8 2 0 0 2 2 2 1 Transglutaminase-like superfamily DDE_Tnp_1 PF01609.21 AAZ33940.1 - 5.8e-36 124.1 1.3 1e-35 123.3 0.9 1.5 2 0 0 2 2 2 1 Transposase DDE domain DUF772 PF05598.11 AAZ33940.1 - 1.7e-19 69.6 0.0 3.6e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 Transposase domain (DUF772) DDE_Tnp_1_6 PF13751.6 AAZ33940.1 - 2.4e-06 27.8 0.8 4.9e-06 26.8 0.8 1.5 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 AAZ33940.1 - 1.5e-05 25.0 0.1 2.4e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 AAZ33940.1 - 0.00018 21.2 0.2 0.00031 20.4 0.2 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Ribosomal_L27A PF00828.19 AAZ33941.1 - 4.4e-30 105.0 3.0 5.3e-30 104.7 3.0 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF4096 PF13340.6 AAZ33942.1 - 5.8e-25 87.3 0.4 1.5e-24 86.0 0.4 1.8 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1 PF01609.21 AAZ33942.1 - 3.2e-14 53.1 0.0 5.7e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AAZ33942.1 - 7.2e-10 39.1 0.2 2.1e-09 37.6 0.2 1.9 1 0 0 1 1 1 1 Transposase DDE domain HTH_Tnp_Tc3_2 PF01498.18 AAZ33942.1 - 0.061 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Transposase Ribosomal_L19 PF01245.20 AAZ33943.1 - 1.6e-48 163.2 1.7 1.8e-48 163.1 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L19 DUF2840 PF11000.8 AAZ33943.1 - 0.047 13.5 0.0 0.06 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2840) HxlR PF01638.17 AAZ33944.1 - 1.7e-20 72.7 0.1 2.5e-20 72.1 0.1 1.2 1 0 0 1 1 1 1 HxlR-like helix-turn-helix MarR PF01047.22 AAZ33944.1 - 0.0016 18.3 0.1 0.0027 17.6 0.1 1.4 1 0 0 1 1 1 1 MarR family PadR PF03551.14 AAZ33944.1 - 0.011 15.7 0.1 0.018 15.0 0.1 1.4 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family HTH_20 PF12840.7 AAZ33944.1 - 0.043 13.9 0.3 0.076 13.1 0.3 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 AAZ33944.1 - 0.063 13.3 0.0 0.09 12.8 0.0 1.3 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain MerR PF00376.23 AAZ33944.1 - 0.083 12.7 0.1 1 9.2 0.1 2.4 1 1 0 1 1 1 0 MerR family regulatory protein HTH_12 PF08461.10 AAZ33944.1 - 0.11 12.4 0.1 0.3 11.1 0.1 1.8 2 0 0 2 2 2 0 Ribonuclease R winged-helix domain DMRL_synthase PF00885.19 AAZ33945.1 - 5.9e-55 185.0 0.6 6.6e-55 184.8 0.6 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase COX3 PF00510.18 AAZ33946.1 - 1e-16 61.6 18.2 1.9e-16 60.7 18.2 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III DUF1691 PF07950.11 AAZ33946.1 - 0.32 11.7 3.9 0.17 12.7 1.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1691) Baseplate_J PF04865.14 AAZ33947.1 - 5.3e-27 94.6 0.1 6.7e-27 94.2 0.1 1.1 1 0 0 1 1 1 1 Baseplate J-like protein TPM_phosphatase PF04536.14 AAZ33948.1 - 2.7e-25 88.9 0.0 4e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 TPM domain DAG1 PF05454.11 AAZ33948.1 - 0.011 15.1 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) CrgA PF06781.12 AAZ33948.1 - 0.089 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Cell division protein CrgA SseB_C PF14581.6 AAZ33948.1 - 0.12 12.5 0.2 3.1 7.9 0.1 2.6 2 1 0 2 2 2 0 SseB protein C-terminal domain T2SSF PF00482.23 AAZ33949.1 - 2.2e-56 189.2 14.5 7e-30 103.6 1.2 2.2 2 0 0 2 2 2 2 Type II secretion system (T2SS), protein F Prok-E2_C PF14459.6 AAZ33949.1 - 0.04 14.1 0.2 11 6.1 0.0 2.4 2 0 0 2 2 2 0 Prokaryotic E2 family C DUF2976 PF11190.8 AAZ33949.1 - 0.99 9.2 5.1 3 7.7 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) LMSTEN PF07988.12 AAZ33950.1 - 0.015 14.8 0.1 0.045 13.2 0.0 1.8 2 0 0 2 2 2 0 LMSTEN motif Erythro_esteras PF05139.14 AAZ33950.1 - 0.2 11.5 2.3 0.33 10.7 2.3 1.4 1 1 0 1 1 1 0 Erythromycin esterase HisKA_3 PF07730.13 AAZ33950.1 - 2.9 8.5 6.1 24 5.5 0.4 3.8 2 1 2 4 4 4 0 Histidine kinase DUF1349 PF07081.11 AAZ33951.1 - 3.5e-42 144.1 0.3 4.2e-42 143.9 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) GH43_C2 PF17851.1 AAZ33951.1 - 0.0034 17.1 0.0 0.0039 16.9 0.0 1.1 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain AsnC_trans_reg PF01037.21 AAZ33952.1 - 1.8e-20 72.7 0.1 2.7e-20 72.1 0.1 1.3 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 AAZ33952.1 - 1.2e-18 66.4 0.1 2.2e-18 65.5 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 AAZ33952.1 - 7.3e-17 60.9 0.3 1.1e-16 60.3 0.3 1.3 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_CodY PF08222.11 AAZ33952.1 - 0.00031 20.2 0.0 0.00074 19.0 0.0 1.7 1 0 0 1 1 1 1 CodY helix-turn-helix domain MarR PF01047.22 AAZ33952.1 - 0.00082 19.2 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 AAZ33952.1 - 0.0084 16.0 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_34 PF13601.6 AAZ33952.1 - 0.015 15.5 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain Rrf2 PF02082.20 AAZ33952.1 - 0.056 13.8 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator HTH_20 PF12840.7 AAZ33952.1 - 0.06 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain TrmB PF01978.19 AAZ33952.1 - 0.13 12.2 0.1 0.39 10.6 0.1 1.8 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB OEP PF02321.18 AAZ33953.1 - 1.1e-41 142.8 28.0 1e-24 87.4 9.8 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein SecG PF03840.14 AAZ33954.1 - 5.5e-19 68.0 8.5 6.8e-19 67.7 8.5 1.1 1 0 0 1 1 1 1 Preprotein translocase SecG subunit DUF4113 PF13438.6 AAZ33955.1 - 5.7e-17 61.5 0.8 1.1e-16 60.7 0.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4113) IMS PF00817.20 AAZ33955.1 - 4.6e-12 46.2 0.0 9.2e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 AAZ33955.1 - 1.9e-11 44.7 0.0 4.7e-11 43.4 0.0 1.6 1 1 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 AAZ33955.1 - 0.00021 21.4 0.0 0.00073 19.7 0.0 2.0 1 0 0 1 1 1 1 IMS family HHH motif Phage_CI_repr PF07022.13 AAZ33957.1 - 0.057 13.5 0.0 0.16 12.1 0.0 1.8 2 0 0 2 2 2 0 Bacteriophage CI repressor helix-turn-helix domain DNA_pol3_delta2 PF13177.6 AAZ33958.1 - 9.8e-44 149.0 0.0 1.4e-43 148.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DNA_pol3_gamma3 PF12169.8 AAZ33958.1 - 2.7e-34 118.1 0.1 8.1e-34 116.6 0.1 1.8 1 0 0 1 1 1 1 DNA polymerase III subunits gamma and tau domain III DNA_pol3_tau_5 PF12170.8 AAZ33958.1 - 2e-19 70.0 0.0 3.5e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III tau subunit V interacting with alpha AAA PF00004.29 AAZ33958.1 - 1.1e-11 45.2 0.0 2.3e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 AAZ33958.1 - 4.2e-08 33.1 0.1 7e-07 29.1 0.0 2.2 1 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 AAZ33958.1 - 1.3e-05 25.2 0.1 0.17 11.9 0.0 2.2 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_5 PF07728.14 AAZ33958.1 - 2.3e-05 24.4 0.0 9.1e-05 22.5 0.0 2.1 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 AAZ33958.1 - 0.00024 20.9 0.0 0.00051 19.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 AAZ33958.1 - 0.00046 19.5 0.0 0.43 9.7 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 AAZ33958.1 - 0.00053 20.3 0.1 0.0019 18.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAZ33958.1 - 0.00067 20.1 0.1 0.0069 16.8 0.1 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 AAZ33958.1 - 0.00087 19.3 0.0 0.0025 17.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain PIF1 PF05970.14 AAZ33958.1 - 0.0014 17.9 0.0 0.0021 17.3 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_18 PF13238.6 AAZ33958.1 - 0.0016 19.0 0.0 0.0033 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 AAZ33958.1 - 0.012 15.7 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TniB PF05621.11 AAZ33958.1 - 0.023 14.1 0.0 0.044 13.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_19 PF13245.6 AAZ33958.1 - 0.024 15.0 0.1 0.099 13.0 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AAZ33958.1 - 0.04 13.6 0.0 0.068 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_assoc_2 PF16193.5 AAZ33958.1 - 0.041 14.2 0.4 4.4 7.7 0.1 2.7 1 1 1 2 2 2 0 AAA C-terminal domain DUF3646 PF12362.8 AAZ33958.1 - 0.043 14.1 0.2 0.13 12.5 0.1 1.9 2 0 0 2 2 1 0 DNA polymerase III gamma and tau subunits C terminal AAA_7 PF12775.7 AAZ33958.1 - 0.063 12.8 0.0 0.46 10.0 0.0 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region SKI PF01202.22 AAZ33958.1 - 0.1 12.7 0.5 0.34 11.0 0.0 2.1 3 0 0 3 3 2 0 Shikimate kinase Rad17 PF03215.15 AAZ33958.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain RsgA_GTPase PF03193.16 AAZ33958.1 - 0.14 12.1 0.0 0.5 10.3 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_23 PF13476.6 AAZ33958.1 - 0.18 12.3 0.0 0.37 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Herpes_Helicase PF02689.14 AAZ33958.1 - 0.21 9.4 0.6 0.32 8.8 0.6 1.1 1 0 0 1 1 1 0 Helicase Sigma54_activat PF00158.26 AAZ33958.1 - 0.22 11.2 0.0 1.5 8.5 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain zf-CXXC PF02008.20 AAZ33958.1 - 0.31 11.1 2.6 0.55 10.3 2.6 1.3 1 0 0 1 1 1 0 CXXC zinc finger domain EAL PF00563.20 AAZ33959.1 - 5.4e-54 183.2 0.4 8.2e-54 182.6 0.4 1.3 1 0 0 1 1 1 1 EAL domain Response_reg PF00072.24 AAZ33959.1 - 5.3e-13 49.1 0.1 1.5e-12 47.6 0.1 1.8 2 0 0 2 2 2 1 Response regulator receiver domain G6PD_C PF02781.16 AAZ33960.1 - 1.1e-118 395.6 0.0 1.4e-118 395.3 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 AAZ33960.1 - 7.6e-51 173.2 0.0 1.5e-50 172.3 0.0 1.5 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain UPF0225 PF17775.1 AAZ33961.1 - 5.6e-28 97.7 0.0 6.8e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 UPF0225 domain SEC-C PF02810.15 AAZ33961.1 - 1.1e-11 44.4 17.4 1.6e-08 34.3 7.6 2.6 2 0 0 2 2 2 2 SEC-C motif S_2TMBeta PF18153.1 AAZ33962.1 - 2.2e-46 157.9 0.0 2.6e-46 157.7 0.0 1.0 1 0 0 1 1 1 1 SMODS-associating 2TM, beta-strand rich effector domain Voltage_CLC PF00654.20 AAZ33962.1 - 0.072 12.3 0.1 0.097 11.9 0.1 1.1 1 0 0 1 1 1 0 Voltage gated chloride channel PLDc PF00614.22 AAZ33962.1 - 0.14 12.4 0.0 18 5.7 0.0 2.4 2 0 0 2 2 2 0 Phospholipase D Active site motif YebG PF07130.12 AAZ33963.1 - 1.9e-23 82.1 0.9 2.3e-23 81.8 0.9 1.1 1 0 0 1 1 1 1 YebG protein DUF3723 PF12520.8 AAZ33963.1 - 0.055 12.2 0.0 0.063 12.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3723) DEAD PF00270.29 AAZ33964.1 - 1.1e-48 165.4 0.4 5.5e-48 163.1 0.1 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AAZ33964.1 - 9.3e-30 103.2 0.0 1.4e-28 99.5 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DbpA PF03880.15 AAZ33964.1 - 2e-18 66.1 0.1 5.1e-18 64.8 0.0 1.8 2 0 0 2 2 2 1 DbpA RNA binding domain ResIII PF04851.15 AAZ33964.1 - 1.3e-05 25.3 0.0 2.3e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DXP_reductoisom PF02670.16 AAZ33964.1 - 0.15 12.7 1.7 7.3 7.3 0.1 2.7 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Na_Ca_ex PF01699.24 AAZ33965.1 - 2.1e-20 73.2 28.4 4.5e-13 49.4 7.2 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein CBM_4_9 PF02018.17 AAZ33966.1 - 0.026 14.8 0.3 5.2 7.3 0.0 2.2 2 0 0 2 2 2 0 Carbohydrate binding domain Response_reg PF00072.24 AAZ33967.1 - 1.6e-23 83.0 0.2 2.5e-23 82.4 0.2 1.3 1 0 0 1 1 1 1 Response regulator receiver domain CheX PF13690.6 AAZ33967.1 - 0.12 12.6 0.9 3.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Chemotaxis phosphatase CheX Acyl-CoA_dh_2 PF08028.11 AAZ33968.1 - 8.5e-22 77.9 4.0 8.5e-22 77.9 4.0 2.5 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 AAZ33968.1 - 1.7e-08 35.1 0.1 6.7e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 AAZ33968.1 - 2.9e-08 33.8 0.0 6e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 AAZ33968.1 - 9.2e-08 32.4 1.6 2e-07 31.3 1.6 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain ThiD2 PF17792.1 AAZ33968.1 - 0.0052 17.2 0.1 0.18 12.2 0.1 2.5 2 0 0 2 2 2 1 ThiD2 family FeoB_Cyto PF17910.1 AAZ33968.1 - 0.028 15.0 0.1 0.5 11.0 0.1 2.4 2 0 0 2 2 2 0 FeoB cytosolic helical domain Ammonium_transp PF00909.21 AAZ33969.1 - 1.2e-119 399.6 46.4 1.3e-119 399.5 46.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family ABC_tran PF00005.27 AAZ33970.1 - 3e-49 167.1 0.1 2.2e-28 99.5 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 AAZ33970.1 - 1.5e-06 28.2 1.4 0.045 13.6 0.5 3.2 2 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AAZ33970.1 - 0.00066 19.4 0.5 0.0064 16.2 0.2 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain TsaE PF02367.17 AAZ33970.1 - 0.0059 16.6 1.3 0.61 10.1 0.2 3.1 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 AAZ33970.1 - 0.0081 16.7 0.1 0.093 13.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 AAZ33970.1 - 0.033 14.6 0.9 0.89 10.0 0.9 2.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 AAZ33970.1 - 0.064 13.2 2.0 5.1 7.0 0.1 2.8 3 0 0 3 3 3 0 NTPase RsgA_GTPase PF03193.16 AAZ33970.1 - 0.066 13.1 0.4 0.59 10.0 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase SMC_N PF02463.19 AAZ33970.1 - 0.11 11.9 0.4 9.6 5.6 0.0 2.8 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_13 PF13166.6 AAZ33970.1 - 0.2 10.3 0.1 0.29 9.8 0.1 1.1 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AAZ33970.1 - 0.23 11.7 2.5 2.1 8.6 0.2 3.1 3 0 0 3 3 3 0 AAA domain Rotamase PF00639.21 AAZ33971.1 - 2.9e-17 63.4 0.0 4.2e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 AAZ33971.1 - 1e-14 55.1 0.0 1.4e-14 54.6 0.0 1.3 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 AAZ33971.1 - 0.0096 16.8 0.0 0.013 16.3 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Mtf2_C PF14061.6 AAZ33971.1 - 0.037 14.2 0.0 0.059 13.6 0.0 1.3 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 DUF1624 PF07786.12 AAZ33972.1 - 2.1e-17 63.4 11.8 2.1e-17 63.4 11.8 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF1624) OpgC_C PF10129.9 AAZ33972.1 - 0.023 13.6 25.3 0.42 9.5 9.2 3.0 1 1 1 2 2 2 0 OpgC protein MHYT PF03707.16 AAZ33972.1 - 0.27 11.4 9.3 0.65 10.2 2.1 3.6 4 0 0 4 4 4 0 Bacterial signalling protein N terminal repeat Orn_Arg_deC_N PF02784.16 AAZ33973.1 - 1.5e-34 119.5 0.0 1.8e-34 119.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 AAZ33973.1 - 2.4e-14 53.3 0.0 3e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ala_racemase_N PF01168.20 AAZ33973.1 - 9.4e-07 28.7 0.1 4.2e-06 26.6 0.1 1.9 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain Sulfotransfer_4 PF17784.1 AAZ33973.1 - 0.022 14.6 0.0 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 Sulfotransferase domain Sororin PF09666.10 AAZ33973.1 - 0.22 11.7 0.0 0.37 11.0 0.0 1.3 1 0 0 1 1 1 0 Sororin protein DUF4096 PF13340.6 AAZ33974.1 - 5.8e-25 87.3 0.4 1.5e-24 86.0 0.4 1.8 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1 PF01609.21 AAZ33974.1 - 3.2e-14 53.1 0.0 5.7e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AAZ33974.1 - 7.2e-10 39.1 0.2 2.1e-09 37.6 0.2 1.9 1 0 0 1 1 1 1 Transposase DDE domain HTH_Tnp_Tc3_2 PF01498.18 AAZ33974.1 - 0.061 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Transposase OEP PF02321.18 AAZ33975.1 - 2e-47 161.4 42.3 3.5e-28 98.7 10.4 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein SUA5 PF03481.13 AAZ33975.1 - 0.083 13.5 1.4 15 6.1 0.1 2.5 2 0 0 2 2 2 0 Putative GTP-binding controlling metal-binding NUDIX PF00293.28 AAZ33976.1 - 1.8e-15 57.1 0.3 2.1e-15 56.9 0.3 1.1 1 0 0 1 1 1 1 NUDIX domain M16C_assoc PF08367.11 AAZ33976.1 - 0.21 10.7 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Peptidase M16C associated DSBA PF01323.20 AAZ33977.1 - 8.7e-19 68.1 2.2 2.6e-15 56.7 0.3 2.1 1 1 1 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 AAZ33977.1 - 4.1e-09 36.8 0.0 6.2e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin PF00085.20 AAZ33977.1 - 1.8e-05 24.7 0.1 0.1 12.6 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_3 PF13192.6 AAZ33977.1 - 9e-05 22.5 0.0 0.0058 16.6 0.0 2.5 2 1 0 2 2 2 1 Thioredoxin domain DUF953 PF06110.11 AAZ33977.1 - 0.00057 19.5 0.0 0.0096 15.5 0.0 2.2 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_5 PF13743.6 AAZ33977.1 - 0.0013 18.4 0.0 0.059 13.0 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.6 AAZ33977.1 - 0.0017 18.7 0.0 0.19 12.1 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 AAZ33977.1 - 0.0024 18.3 0.0 0.019 15.4 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like domain DUF929 PF06053.11 AAZ33977.1 - 0.0045 16.3 0.0 0.0069 15.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF929) Sigma54_activat PF00158.26 AAZ33978.1 - 5.8e-59 198.6 0.0 8.5e-59 198.0 0.0 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AAZ33978.1 - 1.2e-19 70.8 0.0 2.1e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 AAZ33978.1 - 1.4e-07 31.2 0.0 6.8e-07 29.0 0.0 2.2 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 AAZ33978.1 - 2.9e-06 27.3 0.0 5.5e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 AAZ33978.1 - 0.00081 19.8 0.0 0.0013 19.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) HTH_29 PF13551.6 AAZ33978.1 - 0.001 19.0 0.0 0.0038 17.2 0.0 2.0 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.6 AAZ33978.1 - 0.0055 16.5 0.0 0.017 14.9 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_17 PF12728.7 AAZ33978.1 - 0.008 16.3 0.0 0.023 14.9 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 AAZ33978.1 - 0.012 15.7 0.0 0.043 14.0 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain AAA_16 PF13191.6 AAZ33978.1 - 0.013 15.9 1.2 0.038 14.4 1.2 2.1 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 AAZ33978.1 - 0.013 15.4 0.1 7 6.5 0.0 2.8 2 1 0 2 2 2 0 NACHT domain HTH_50 PF18024.1 AAZ33978.1 - 0.02 14.5 0.1 0.043 13.4 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain DUF815 PF05673.13 AAZ33978.1 - 0.062 12.4 0.0 8.7 5.4 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF815) HTH_22 PF13309.6 AAZ33978.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 HTH domain IstB_IS21 PF01695.17 AAZ33978.1 - 0.12 12.0 0.0 0.35 10.6 0.0 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 AAZ33978.1 - 0.13 11.7 0.1 5.7 6.3 0.0 2.6 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI HTH_18 PF12833.7 AAZ33979.1 - 3.9e-18 65.5 2.2 3.7e-17 62.4 0.2 2.5 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAZ33979.1 - 5.1e-11 42.4 0.1 1.9e-06 27.8 0.0 2.9 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family DBI_PRT PF02277.17 AAZ33980.1 - 2.7e-128 427.9 12.9 3e-128 427.7 12.9 1.0 1 0 0 1 1 1 1 Phosphoribosyltransferase MAAL_C PF07476.11 AAZ33980.1 - 0.038 13.2 0.5 0.073 12.2 0.5 1.4 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus Aldolase PF01081.19 AAZ33981.1 - 1.8e-32 112.3 0.4 4.6e-32 111.0 0.3 1.6 1 1 1 2 2 2 1 KDPG and KHG aldolase Amino_oxidase PF01593.24 AAZ33982.1 - 4.3e-45 154.8 0.5 1.5e-44 153.0 0.5 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 AAZ33982.1 - 1e-10 41.7 0.1 2.7e-10 40.4 0.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AAZ33982.1 - 2.4e-10 40.5 0.2 1.6e-09 37.9 0.3 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 AAZ33982.1 - 1.1e-07 31.3 0.9 1.1e-07 31.3 0.9 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 AAZ33982.1 - 2.9e-07 30.0 0.0 9e-05 21.8 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AAZ33982.1 - 3e-06 26.8 0.1 6.4e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 AAZ33982.1 - 9.7e-06 24.5 1.8 0.00028 19.7 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 AAZ33982.1 - 1.6e-05 24.3 3.1 0.037 13.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 AAZ33982.1 - 1.7e-05 24.2 0.6 3.3e-05 23.3 0.1 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 AAZ33982.1 - 3.9e-05 24.1 0.8 0.00073 20.1 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AAZ33982.1 - 0.00056 19.1 0.6 0.00088 18.5 0.6 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 AAZ33982.1 - 0.0012 18.1 0.3 0.0026 17.1 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 AAZ33982.1 - 0.0019 17.3 1.3 0.0063 15.6 0.2 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein YjeF_N PF03853.15 AAZ33982.1 - 0.0061 16.5 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 YjeF-related protein N-terminus NAD_binding_9 PF13454.6 AAZ33982.1 - 0.024 14.6 3.0 4 7.4 0.4 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding MCRA PF06100.11 AAZ33982.1 - 0.23 10.2 1.4 0.25 10.1 0.1 1.6 2 0 0 2 2 2 0 MCRA family DUF2076 PF09849.9 AAZ33982.1 - 5.5 7.0 22.4 1.1e+04 -3.9 22.5 3.1 1 1 0 1 1 0 0 Uncharacterized protein conserved in bacteria (DUF2076) PGK PF00162.19 AAZ33983.1 - 3.3e-137 457.5 0.5 3.8e-137 457.3 0.5 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Peptidase_S24 PF00717.23 AAZ33983.1 - 0.15 12.0 0.2 1.4 8.9 0.0 2.2 2 0 0 2 2 2 0 Peptidase S24-like HBM PF16591.5 AAZ33984.1 - 1.1e-56 192.1 12.3 1.1e-56 192.1 12.3 3.4 3 0 0 3 3 3 1 Helical bimodular sensor domain MCPsignal PF00015.21 AAZ33984.1 - 8.9e-46 155.8 27.7 8.9e-46 155.8 27.7 3.9 2 1 1 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AAZ33984.1 - 5.7e-10 39.4 0.5 5.7e-10 39.4 0.5 4.2 5 0 0 5 5 5 1 HAMP domain Laminin_II PF06009.12 AAZ33984.1 - 0.0023 18.0 40.8 0.18 11.8 2.7 4.6 3 2 1 4 4 4 3 Laminin Domain II Fib_alpha PF08702.10 AAZ33984.1 - 0.07 13.3 17.3 0.17 12.1 2.0 4.3 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family 4HB_MCP_1 PF12729.7 AAZ33984.1 - 0.1 12.2 19.8 0.032 13.8 0.8 5.3 2 2 2 5 5 5 0 Four helix bundle sensory module for signal transduction TMEM154 PF15102.6 AAZ33984.1 - 0.13 12.2 0.1 0.13 12.2 0.1 3.1 3 0 0 3 3 3 0 TMEM154 protein family UPF0444 PF15475.6 AAZ33984.1 - 0.25 11.6 2.9 0.73 10.1 0.2 2.9 3 0 0 3 3 3 0 Transmembrane protein C12orf23, UPF0444 T3SS_needle_E PF08988.10 AAZ33984.1 - 0.26 11.5 5.6 0.47 10.6 0.2 4.0 3 0 0 3 3 3 0 Type III secretion system, cytoplasmic E component of needle PLU-1 PF08429.11 AAZ33984.1 - 1.1 8.3 11.0 1.6 7.8 0.3 3.0 2 1 0 2 2 2 0 PLU-1-like protein DUF948 PF06103.11 AAZ33984.1 - 3.1 8.1 42.2 6.3 7.1 11.4 7.2 3 2 3 6 6 6 0 Bacterial protein of unknown function (DUF948) Abi_2 PF07751.11 AAZ33985.1 - 4.9e-07 30.2 0.2 7.7e-07 29.5 0.2 1.3 1 0 0 1 1 1 1 Abi-like protein DUF551 PF04448.12 AAZ33985.1 - 0.0096 16.8 0.8 0.091 13.7 0.1 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF551) HEPN_Swt1 PF18731.1 AAZ33985.1 - 0.059 13.7 0.4 1.4 9.2 0.4 2.3 1 1 0 1 1 1 0 Swt1-like HEPN Hydrolase_4 PF12146.8 AAZ33986.1 - 2.4e-22 79.4 0.0 3.9e-14 52.5 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AAZ33986.1 - 3.3e-14 54.0 0.0 1.6e-09 38.7 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AAZ33986.1 - 2.4e-10 40.5 0.1 4.7e-06 26.4 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 AAZ33986.1 - 1.5e-06 27.9 0.0 5.8e-06 25.9 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 AAZ33986.1 - 2.7e-06 27.2 0.0 0.014 15.0 0.0 2.1 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.13 AAZ33986.1 - 1.7e-05 24.6 0.0 3.3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) AXE1 PF05448.12 AAZ33986.1 - 0.00018 20.3 0.0 0.2 10.3 0.0 2.4 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) DLH PF01738.18 AAZ33986.1 - 0.00032 20.3 0.0 0.0045 16.6 0.0 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Lipase_3 PF01764.25 AAZ33986.1 - 0.001 19.0 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.7 AAZ33986.1 - 0.0012 18.6 0.0 0.2 11.4 0.0 2.8 3 0 0 3 3 3 1 Alpha/beta hydrolase family PhoPQ_related PF10142.9 AAZ33986.1 - 0.0017 17.1 0.0 0.0025 16.5 0.0 1.2 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Abhydrolase_4 PF08386.10 AAZ33986.1 - 0.0022 18.1 0.0 0.004 17.2 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Thioesterase PF00975.20 AAZ33986.1 - 0.0037 17.4 0.0 0.0064 16.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Chlorophyllase2 PF12740.7 AAZ33986.1 - 0.018 14.0 0.0 0.026 13.4 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_2 PF02230.16 AAZ33986.1 - 0.029 14.2 0.0 0.39 10.5 0.0 2.4 2 1 0 3 3 3 0 Phospholipase/Carboxylesterase Esterase PF00756.20 AAZ33986.1 - 0.053 13.1 0.0 2.1 7.9 0.0 2.6 3 0 0 3 3 3 0 Putative esterase bact-PGI_C PF10432.9 AAZ33986.1 - 0.063 13.3 0.0 6.1 6.9 0.0 2.3 2 0 0 2 2 2 0 Bacterial phospho-glucose isomerase C-terminal SIS domain tRNA-synt_1 PF00133.22 AAZ33987.1 - 8.7e-216 717.8 0.0 1.8e-214 713.5 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 AAZ33987.1 - 7.9e-46 155.8 0.0 1.5e-45 154.8 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Val_tRNA-synt_C PF10458.9 AAZ33987.1 - 8.1e-18 64.5 2.3 2.3e-17 63.0 2.3 1.8 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1g PF09334.11 AAZ33987.1 - 2.8e-15 56.0 0.8 5.7e-05 22.0 0.0 4.6 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 AAZ33987.1 - 3.6e-08 33.1 0.0 2.7e-07 30.3 0.0 2.0 1 1 1 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 ABC_tran_CTD PF16326.5 AAZ33987.1 - 0.0092 16.2 0.4 0.0092 16.2 0.4 2.0 2 0 0 2 2 2 1 ABC transporter C-terminal domain Phosphodiest PF01663.22 AAZ33988.1 - 1.4e-17 64.3 0.8 1.3e-15 57.9 0.8 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase PglZ PF08665.12 AAZ33988.1 - 3.9e-06 27.1 0.1 0.0012 19.0 0.1 2.3 2 1 0 2 2 2 2 PglZ domain Metalloenzyme PF01676.18 AAZ33988.1 - 5.1e-05 22.8 0.4 0.00019 20.9 0.4 1.8 1 1 0 1 1 1 1 Metalloenzyme superfamily TPR_14 PF13428.6 AAZ33989.1 - 1.9e-30 102.9 46.4 1.8e-05 25.1 0.3 12.4 4 4 9 13 13 13 10 Tetratricopeptide repeat TPR_16 PF13432.6 AAZ33989.1 - 3.7e-30 104.3 39.9 7e-07 29.8 0.1 9.1 5 2 2 9 9 9 6 Tetratricopeptide repeat TPR_19 PF14559.6 AAZ33989.1 - 2.5e-27 95.1 42.1 2.3e-09 37.6 0.2 8.4 4 1 4 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.17 AAZ33989.1 - 3.8e-21 73.4 32.6 5.6e-05 22.9 0.0 12.0 12 0 0 12 12 12 4 Tetratricopeptide repeat TPR_6 PF13174.6 AAZ33989.1 - 1.9e-18 65.8 27.9 0.0039 17.7 0.0 12.9 13 0 0 13 13 13 4 Tetratricopeptide repeat TPR_17 PF13431.6 AAZ33989.1 - 3.8e-17 61.3 10.6 0.031 14.7 0.3 9.3 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 AAZ33989.1 - 9.9e-16 57.8 31.8 3.1e-09 37.0 0.3 8.9 6 1 4 10 10 10 3 Tetratricopeptide repeat TPR_8 PF13181.6 AAZ33989.1 - 7.6e-15 53.8 5.0 0.022 15.0 0.0 8.8 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_11 PF13414.6 AAZ33989.1 - 8.2e-11 41.4 2.2 0.36 10.5 0.0 7.1 8 0 0 8 8 7 3 TPR repeat TPR_9 PF13371.6 AAZ33989.1 - 8.3e-11 41.9 31.1 0.0048 17.0 0.5 7.0 4 2 2 6 6 6 4 Tetratricopeptide repeat ANAPC3 PF12895.7 AAZ33989.1 - 1.4e-10 41.3 8.9 0.006 16.8 0.2 6.3 4 2 2 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 AAZ33989.1 - 3.7e-09 36.0 18.9 0.00085 19.0 0.0 9.5 12 0 0 12 12 11 1 Tetratricopeptide repeat TPR_20 PF14561.6 AAZ33989.1 - 1.2e-08 35.1 24.6 0.094 13.1 0.2 7.4 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_10 PF13374.6 AAZ33989.1 - 3.4e-08 33.1 37.3 0.0056 16.5 0.5 9.3 10 0 0 10 10 9 3 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 AAZ33989.1 - 1.1e-07 31.6 11.4 0.085 12.5 0.3 4.6 3 2 2 5 5 5 3 Bacterial type III secretion protein (HrpB1_HrpK) TPR_7 PF13176.6 AAZ33989.1 - 1.7e-07 30.8 13.3 0.91 9.7 0.0 8.1 8 2 1 9 9 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 AAZ33989.1 - 1.6e-06 27.6 25.5 0.00015 21.1 9.5 4.7 1 1 2 4 4 4 2 Tetratricopeptide repeat Coatomer_E PF04733.14 AAZ33989.1 - 3.7e-06 26.6 0.2 0.0099 15.3 0.1 2.9 2 2 0 2 2 2 2 Coatomer epsilon subunit TPR_21 PF09976.9 AAZ33989.1 - 3.7e-05 23.5 27.8 0.00082 19.1 3.1 5.0 3 2 3 6 6 6 2 Tetratricopeptide repeat-like domain NARP1 PF12569.8 AAZ33989.1 - 4.7e-05 22.5 9.2 0.01 14.8 0.5 3.7 2 2 2 4 4 4 2 NMDA receptor-regulated protein 1 Fis1_TPR_C PF14853.6 AAZ33989.1 - 0.00012 22.1 4.0 0.27 11.3 0.0 5.3 5 2 2 7 7 7 1 Fis1 C-terminal tetratricopeptide repeat DUF3808 PF10300.9 AAZ33989.1 - 0.0012 17.7 1.6 0.11 11.3 0.1 3.4 3 1 1 4 4 4 1 Protein of unknown function (DUF3808) DUF4810 PF16068.5 AAZ33989.1 - 0.014 15.9 0.1 22 5.7 0.0 4.4 3 2 2 5 5 3 0 Domain of unknown function (DUF4810) ChAPs PF09295.10 AAZ33989.1 - 0.015 14.3 0.5 0.44 9.5 0.1 2.4 2 1 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) RuvA_C PF07499.13 AAZ33989.1 - 0.17 12.3 2.1 37 4.9 0.1 3.7 3 0 0 3 3 3 0 RuvA, C-terminal domain FMN_red PF03358.15 AAZ33990.1 - 7.2e-09 35.6 0.0 1.2e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 AAZ33990.1 - 0.0017 18.1 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 AAZ33990.1 - 0.0021 18.3 0.0 0.0033 17.6 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 AAZ33990.1 - 0.021 15.1 0.0 0.11 12.8 0.0 1.9 2 0 0 2 2 2 0 Flavodoxin domain Colicin_V PF02674.16 AAZ33991.1 - 1.5e-34 119.1 14.0 1.9e-34 118.7 14.0 1.1 1 0 0 1 1 1 1 Colicin V production protein GN3L_Grn1 PF08701.11 AAZ33991.1 - 0.22 11.6 0.0 0.32 11.1 0.0 1.1 1 0 0 1 1 1 0 GNL3L/Grn1 putative GTPase TssN PF17555.2 AAZ33991.1 - 0.4 10.0 2.7 0.58 9.5 2.7 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssN DUF2085 PF09858.9 AAZ33991.1 - 1.3 9.6 6.5 0.76 10.3 1.7 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2085) DUF4131 PF13567.6 AAZ33991.1 - 2.1 8.0 7.0 0.54 9.9 3.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF2613 PF11021.8 AAZ33993.1 - 0.021 14.9 0.0 0.93 9.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) RVT_1 PF00078.27 AAZ33994.1 - 4.7e-12 45.9 0.8 2.4e-11 43.6 0.2 2.2 1 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RUN PF02759.19 AAZ33994.1 - 0.0093 15.9 4.4 0.058 13.4 0.3 3.2 3 1 0 3 3 3 1 RUN domain MA3 PF02847.17 AAZ33994.1 - 0.014 15.4 0.5 0.085 12.8 0.1 2.5 2 0 0 2 2 2 0 MA3 domain L27_1 PF09058.10 AAZ33994.1 - 0.17 11.9 1.2 0.51 10.4 0.5 2.2 2 0 0 2 2 2 0 L27_1 Baculo_PEP_N PF04512.12 AAZ33995.1 - 0.1 12.9 0.0 0.1 12.9 0.0 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, N terminus RNA_pol_Rpb5_C PF01191.19 AAZ33995.1 - 0.11 12.4 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain SmpA_OmlA PF04355.13 AAZ33996.1 - 9.3e-06 25.3 0.1 1.6e-05 24.6 0.0 1.4 2 0 0 2 2 2 1 SmpA / OmlA family DUF3862 PF12978.7 AAZ33996.1 - 0.038 13.8 0.0 0.13 12.0 0.0 1.7 1 1 1 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3862) DUF5061 PF16587.5 AAZ33996.1 - 0.054 13.6 0.1 0.065 13.3 0.1 1.1 1 0 0 1 1 1 0 17 kDa common-antigen outer membrane protein Acetyltransf_1 PF00583.25 AAZ33997.1 - 3e-13 50.0 0.0 3.7e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AAZ33997.1 - 6.4e-10 39.0 0.0 8.9e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAZ33997.1 - 6.5e-08 32.9 0.0 9.1e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AAZ33997.1 - 1.9e-05 25.3 0.0 2.1e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AAZ33997.1 - 2e-05 24.7 0.0 2.4e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 AAZ33997.1 - 0.00047 19.9 0.0 0.00066 19.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ FR47 PF08445.10 AAZ33997.1 - 0.00088 19.2 0.0 0.002 18.1 0.0 1.5 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_18 PF18014.1 AAZ33997.1 - 0.0081 16.0 0.0 0.15 11.9 0.1 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AAZ33997.1 - 0.05 13.7 0.0 0.072 13.2 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 AAZ33997.1 - 0.15 12.1 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase PAS_3 PF08447.12 AAZ33998.1 - 1.7e-40 137.2 0.1 4.1e-21 75.1 0.0 2.4 2 0 0 2 2 2 2 PAS fold MCPsignal PF00015.21 AAZ33998.1 - 2.5e-28 99.0 5.2 4.1e-28 98.3 5.2 1.3 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain PAS_9 PF13426.7 AAZ33998.1 - 1.3e-08 35.0 0.0 0.0038 17.5 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 AAZ33998.1 - 2e-08 34.2 0.0 0.0027 17.7 0.0 2.8 2 1 0 2 2 2 2 PAS fold PAS_4 PF08448.10 AAZ33998.1 - 0.02 15.1 0.5 8.5 6.7 0.0 3.0 3 1 0 3 3 3 0 PAS fold Sugarporin_N PF11471.8 AAZ33998.1 - 0.27 11.2 3.5 0.98 9.4 3.5 2.0 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Pox_A_type_inc PF04508.12 AAZ33998.1 - 0.45 10.4 0.1 0.45 10.4 0.1 2.1 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Transp_cyt_pur PF02133.15 AAZ33999.1 - 1.6e-21 76.6 19.8 1.9e-21 76.4 19.8 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin CorC_HlyC PF03471.17 AAZ34000.1 - 1.5e-19 69.8 0.1 6.2e-19 67.8 0.0 2.0 2 0 0 2 2 2 1 Transporter associated domain CBS PF00571.28 AAZ34000.1 - 4.9e-12 46.1 2.1 1.5e-05 25.3 0.1 2.6 3 0 0 3 3 3 2 CBS domain Transposase_mut PF00872.18 AAZ34001.1 - 5.4e-116 387.6 0.0 6.7e-116 387.3 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ34001.1 - 7.7e-05 23.0 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain DUF4844 PF16133.5 AAZ34001.1 - 0.23 12.0 0.0 0.55 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) MFS_1 PF07690.16 AAZ34002.1 - 1.2e-07 31.0 37.0 1.2e-07 31.0 37.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2070 PF09843.9 AAZ34002.1 - 2.3 6.4 12.8 1.5 7.0 11.0 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) QSregVF_b PF12843.7 AAZ34003.1 - 3.5e-30 103.7 0.5 4e-30 103.5 0.5 1.0 1 0 0 1 1 1 1 Putative quorum-sensing-regulated virulence factor PPDK_N PF01326.19 AAZ34004.1 - 9.6e-35 120.4 0.4 1.5e-25 90.2 0.3 2.5 2 1 1 3 3 3 2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 AAZ34004.1 - 1.4e-06 27.9 0.0 4.5e-06 26.3 0.0 1.9 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain DUF962 PF06127.11 AAZ34005.1 - 6.4e-27 93.5 1.2 4.2e-26 90.8 1.2 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF962) 7TM-7TMR_HD PF07698.11 AAZ34005.1 - 0.039 13.7 7.0 0.048 13.4 6.5 1.4 1 1 0 1 1 1 0 7TM receptor with intracellular HD hydrolase TauE PF01925.19 AAZ34005.1 - 0.053 13.1 14.5 0.074 12.7 14.5 1.3 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE HlyIII PF03006.20 AAZ34005.1 - 0.082 12.6 0.2 0.082 12.6 0.2 2.1 1 1 2 3 3 3 0 Haemolysin-III related AC_N PF16214.5 AAZ34005.1 - 0.27 10.3 2.6 0.36 9.9 2.6 1.1 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region FA_desaturase PF00487.24 AAZ34005.1 - 6.7 6.5 16.0 3.5 7.4 5.6 2.2 1 1 1 2 2 2 0 Fatty acid desaturase Bac_luciferase PF00296.20 AAZ34006.1 - 2.1e-91 306.6 1.1 2.4e-91 306.4 1.1 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase TauE PF01925.19 AAZ34009.1 - 7.3e-25 88.0 43.7 8.5e-25 87.8 43.7 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE GGDEF PF00990.21 AAZ34011.1 - 1.3e-46 158.3 0.5 2.2e-45 154.3 0.0 2.2 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain dCache_1 PF02743.18 AAZ34011.1 - 7.1e-15 55.5 1.5 1.3e-14 54.6 0.6 1.7 2 0 0 2 2 2 1 Cache domain DUF4381 PF14316.6 AAZ34011.1 - 0.0025 18.1 6.9 0.026 14.7 1.2 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4381) TIM21 PF08294.11 AAZ34011.1 - 0.15 12.0 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 TIM21 TPR_21 PF09976.9 AAZ34011.1 - 1.7 8.4 7.3 4.2 7.0 4.4 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat-like domain OmpA PF00691.20 AAZ34012.1 - 1.8e-26 92.3 0.3 5.6e-26 90.7 0.0 1.9 2 0 0 2 2 2 1 OmpA family DUF4398 PF14346.6 AAZ34012.1 - 1.9e-11 44.4 8.2 1.9e-11 44.4 8.2 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4398) CHASE3 PF05227.13 AAZ34012.1 - 0.00078 19.4 7.2 0.0016 18.3 7.2 1.6 1 0 0 1 1 1 1 CHASE3 domain Pilus_CpaD PF09476.10 AAZ34012.1 - 0.0065 16.2 6.2 0.077 12.7 0.0 2.3 1 1 1 2 2 2 2 Pilus biogenesis CpaD protein (pilus_cpaD) Swi5 PF07061.11 AAZ34012.1 - 0.075 13.1 0.3 0.29 11.2 0.0 2.1 1 1 2 3 3 3 0 Swi5 Mqo PF06039.15 AAZ34013.1 - 2.4e-230 765.1 0.0 2.8e-230 764.9 0.0 1.0 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) DAO PF01266.24 AAZ34013.1 - 1.7e-09 37.7 0.0 2.2e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 AAZ34013.1 - 0.0001 21.7 0.2 0.001 18.4 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 AAZ34013.1 - 0.057 12.6 0.0 0.66 9.2 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 AAZ34013.1 - 0.074 12.3 0.0 0.22 10.8 0.0 1.8 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase K_oxygenase PF13434.6 AAZ34013.1 - 0.09 11.9 0.1 9.1 5.3 0.1 2.7 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Acetyltransf_10 PF13673.7 AAZ34014.1 - 2.2e-23 82.6 0.0 2.5e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAZ34014.1 - 3.2e-12 46.7 0.0 3.9e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAZ34014.1 - 1e-10 41.9 0.1 1.6e-10 41.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.6 AAZ34014.1 - 2.3e-05 25.0 0.0 0.004 17.8 0.0 2.4 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAZ34014.1 - 0.0012 18.8 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 AAZ34014.1 - 0.017 15.2 0.0 0.032 14.3 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acyl-CoA_dh_M PF02770.19 AAZ34015.1 - 1.4e-08 34.8 0.0 2.4e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain DUF1330 PF07045.11 AAZ34016.1 - 2.4e-38 130.4 0.7 2.6e-38 130.3 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1330) Peptidase_M24 PF00557.24 AAZ34017.1 - 1.3e-64 217.8 0.1 2.5e-64 216.8 0.1 1.4 2 0 0 2 2 2 1 Metallopeptidase family M24 AMP_N PF05195.16 AAZ34017.1 - 1.3e-36 125.0 0.0 2.2e-36 124.3 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Cupin_2 PF07883.11 AAZ34017.1 - 0.013 15.1 0.1 4.7 7.0 0.0 2.5 2 0 0 2 2 2 0 Cupin domain Creatinase_N PF01321.18 AAZ34017.1 - 0.13 13.0 0.0 0.26 12.0 0.0 1.6 1 0 0 1 1 1 0 Creatinase/Prolidase N-terminal domain EAL PF00563.20 AAZ34018.1 - 3.1e-65 220.0 0.0 5.1e-65 219.3 0.0 1.3 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AAZ34018.1 - 6.1e-37 126.8 0.0 1.4e-36 125.7 0.0 1.6 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Holin_BlyA PF05102.12 AAZ34018.1 - 0.01 15.8 0.5 0.028 14.4 0.5 1.7 1 0 0 1 1 1 1 holin, BlyA family FTSW_RODA_SPOVE PF01098.19 AAZ34018.1 - 0.18 10.8 11.9 0.29 10.1 10.7 1.9 2 1 0 2 2 2 0 Cell cycle protein DUF3522 PF12036.8 AAZ34018.1 - 1.8 8.8 14.4 2.6 8.3 7.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3522) Bactofilin PF04519.13 AAZ34019.1 - 0.021 15.1 0.7 0.034 14.5 0.2 1.6 2 0 0 2 2 2 0 Polymer-forming cytoskeletal CDO_I PF05995.12 AAZ34020.1 - 3.3e-08 33.0 0.0 4.3e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I Auxin_BP PF02041.16 AAZ34020.1 - 0.0036 17.0 0.0 0.0049 16.5 0.0 1.2 1 0 0 1 1 1 1 Auxin binding protein PCO_ADO PF07847.12 AAZ34020.1 - 0.036 13.5 0.0 0.051 13.0 0.0 1.4 1 1 0 1 1 1 0 PCO_ADO SOBP PF15279.6 AAZ34022.1 - 0.18 12.3 19.2 0.29 11.7 19.2 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein DUF3584 PF12128.8 AAZ34022.1 - 1.4 6.3 38.3 1.8 6.0 38.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Presenilin PF01080.17 AAZ34022.1 - 4.3 6.0 31.8 5.7 5.6 31.8 1.1 1 0 0 1 1 1 0 Presenilin CDK5_activator PF03261.15 AAZ34022.1 - 4.3 6.8 22.3 5.7 6.4 22.3 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein AsnC_trans_reg PF01037.21 AAZ34023.1 - 2.3e-21 75.6 0.0 3.7e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_AsnC-type PF13404.6 AAZ34023.1 - 2e-20 72.3 0.3 3.5e-20 71.5 0.3 1.4 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 AAZ34023.1 - 3.6e-20 71.2 0.4 6.9e-20 70.3 0.4 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 AAZ34023.1 - 1.9e-05 24.5 0.0 3.7e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 AAZ34023.1 - 0.0042 17.1 0.0 0.0083 16.2 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_47 PF16221.5 AAZ34023.1 - 0.0057 16.2 0.0 0.0085 15.6 0.0 1.3 1 0 0 1 1 1 1 winged helix-turn-helix MarR_2 PF12802.7 AAZ34023.1 - 0.011 15.6 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 MarR family HTH_11 PF08279.12 AAZ34023.1 - 0.017 15.1 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 HTH domain GntR PF00392.21 AAZ34023.1 - 0.017 14.8 0.1 0.041 13.6 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family Sigma70_r4 PF04545.16 AAZ34023.1 - 0.057 13.0 0.5 0.16 11.5 0.5 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_Crp_2 PF13545.6 AAZ34023.1 - 0.062 13.3 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain LexA_DNA_bind PF01726.16 AAZ34023.1 - 0.082 12.7 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 LexA DNA binding domain HTH_Tnp_Tc3_2 PF01498.18 AAZ34023.1 - 0.11 12.7 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Transposase CrtC PF07143.11 AAZ34024.1 - 2e-54 184.7 8.3 3e-54 184.1 8.3 1.3 1 0 0 1 1 1 1 CrtC N-terminal lipocalin domain Lipocalin_9 PF17186.4 AAZ34024.1 - 2.7e-39 134.4 0.4 5.5e-39 133.4 0.4 1.5 1 0 0 1 1 1 1 Lipocalin-like domain DAHP_synth_1 PF00793.20 AAZ34025.1 - 4.4e-84 281.6 0.0 5.4e-84 281.3 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family EAL PF00563.20 AAZ34026.1 - 5.9e-71 238.8 0.0 1.3e-70 237.6 0.0 1.6 2 0 0 2 2 2 1 EAL domain GAF PF01590.26 AAZ34026.1 - 2.5e-10 41.1 0.0 1.4e-09 38.6 0.0 2.3 3 0 0 3 3 3 1 GAF domain GGDEF PF00990.21 AAZ34026.1 - 4.2e-10 39.6 0.0 8.6e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain GAF_3 PF13492.6 AAZ34026.1 - 0.014 15.7 0.0 0.047 14.0 0.0 1.9 2 0 0 2 2 2 0 GAF domain FTR1 PF03239.14 AAZ34027.1 - 3.7e-55 187.3 19.5 6.3e-55 186.5 19.5 1.3 1 1 0 1 1 1 1 Iron permease FTR1 family DUF2085 PF09858.9 AAZ34027.1 - 2.1 8.9 8.6 0.26 11.8 0.5 2.9 3 0 0 3 3 3 0 Predicted membrane protein (DUF2085) Peripla_BP_1 PF00532.21 AAZ34028.1 - 5.4e-28 98.2 0.0 7e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_3 PF13377.6 AAZ34028.1 - 1e-27 97.5 0.7 2.2e-27 96.4 0.2 1.8 2 0 0 2 2 2 1 Periplasmic binding protein-like domain LacI PF00356.21 AAZ34028.1 - 4.4e-14 52.0 0.0 1.1e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 AAZ34028.1 - 6.6e-14 52.1 0.0 8.6e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain DctQ PF04290.12 AAZ34029.1 - 4.6e-20 71.9 10.2 4.6e-20 71.9 10.2 1.2 1 1 0 1 1 1 1 Tripartite ATP-independent periplasmic transporters, DctQ component DUF1232 PF06803.12 AAZ34030.1 - 2.4e-13 49.6 7.6 2.4e-13 49.6 7.6 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1232) ACR_tran PF00873.19 AAZ34031.1 - 7.4e-148 494.0 12.2 9.2e-148 493.7 12.2 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family ABC_membrane PF00664.23 AAZ34031.1 - 0.0004 20.1 1.9 0.0004 20.1 1.9 2.7 2 0 0 2 2 2 1 ABC transporter transmembrane region OST3_OST6 PF04756.13 AAZ34031.1 - 0.16 11.3 0.6 0.76 9.1 0.6 2.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family HTH_18 PF12833.7 AAZ34032.1 - 8.5e-21 74.0 1.7 1.3e-20 73.4 0.5 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAZ34032.1 - 1.5e-09 37.7 0.1 1.8e-07 31.1 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family AraC_binding PF02311.19 AAZ34032.1 - 3.5e-05 23.7 5.0 0.00019 21.4 5.0 2.1 1 1 0 1 1 1 1 AraC-like ligand binding domain Pepdidase_M14_N PF18027.1 AAZ34033.1 - 2.3e-35 121.2 0.4 4.5e-35 120.3 0.4 1.5 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain Peptidase_M14 PF00246.24 AAZ34033.1 - 9.2e-22 78.2 0.0 2.6e-21 76.7 0.0 1.6 1 1 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 AAZ34033.1 - 0.016 14.3 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family DUF2817 PF10994.8 AAZ34033.1 - 0.042 13.2 0.0 0.066 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) ATP-synt_DE_N PF02823.16 AAZ34034.1 - 3.4e-30 103.8 0.1 4.6e-30 103.4 0.1 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain ATP-synt_DE PF00401.20 AAZ34034.1 - 2.3e-07 30.9 7.7 3.4e-07 30.4 7.7 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, long alpha-helix domain CobN-Mg_chel PF02514.16 AAZ34034.1 - 0.034 11.9 0.1 0.042 11.6 0.1 1.0 1 0 0 1 1 1 0 CobN/Magnesium Chelatase DUF4198 PF10670.9 AAZ34035.1 - 3e-16 60.4 0.2 3.7e-16 60.1 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4198) LysR_substrate PF03466.20 AAZ34036.1 - 4.1e-40 137.4 6.3 5.8e-40 136.9 6.3 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ34036.1 - 1.8e-21 75.9 2.4 4.2e-21 74.7 2.4 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 AAZ34036.1 - 0.08 12.8 1.8 0.55 10.2 0.2 2.9 3 0 0 3 3 3 0 MarR family Mg_chelatase PF01078.21 AAZ34037.1 - 4.2e-47 160.2 0.0 7.1e-47 159.5 0.0 1.4 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI Mg_chelatase_C PF13335.6 AAZ34037.1 - 7.2e-26 90.7 6.1 7.2e-26 90.7 6.1 1.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI C-terminal MCM PF00493.23 AAZ34037.1 - 1.5e-06 27.5 0.0 2.3e-06 26.9 0.0 1.4 1 1 0 1 1 1 1 MCM P-loop domain AAA_5 PF07728.14 AAZ34037.1 - 8.6e-05 22.6 0.0 0.00028 20.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) MAPEG PF01124.18 AAZ34038.1 - 1.1e-22 80.3 7.5 1.3e-22 80.1 7.5 1.0 1 0 0 1 1 1 1 MAPEG family DUF2813 PF11398.8 AAZ34039.1 - 2.4e-08 33.7 0.0 2.4e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2813) AAA_23 PF13476.6 AAZ34039.1 - 2.6e-08 34.6 0.0 2.6e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 AAZ34039.1 - 3.9e-08 33.4 0.0 4.4e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 AAZ34039.1 - 2e-07 30.7 0.0 2.5e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AAZ34039.1 - 0.00017 21.5 0.0 0.00025 21.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_27 PF13514.6 AAZ34039.1 - 0.00034 20.3 0.0 0.00051 19.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 AAZ34039.1 - 0.0022 18.5 0.0 0.0024 18.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 AAZ34039.1 - 0.0053 16.5 0.0 0.0082 15.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_ATPase PF09818.9 AAZ34039.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class SBP_bac_5 PF00496.22 AAZ34040.1 - 3.2e-65 220.6 4.6 4.3e-65 220.1 4.6 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle GYR PF02756.14 AAZ34040.1 - 3.7 7.3 6.4 0.3 10.8 1.5 1.7 2 0 0 2 2 2 0 GYR motif FtsX PF02687.21 AAZ34041.1 - 1.6e-16 60.5 8.0 1.5e-13 51.0 3.0 3.2 3 0 0 3 3 3 2 FtsX-like permease family MacB_PCD PF12704.7 AAZ34041.1 - 1.8e-14 54.6 0.3 1.8e-14 54.6 0.3 1.8 2 0 0 2 2 2 1 MacB-like periplasmic core domain 7tm_7 PF08395.12 AAZ34041.1 - 0.037 13.2 0.8 2.5 7.2 0.0 2.2 2 0 0 2 2 2 0 7tm Chemosensory receptor Peptidase_S37 PF05576.11 AAZ34041.1 - 0.12 11.1 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 PS-10 peptidase S37 MscL PF01741.18 AAZ34041.1 - 0.8 10.0 6.8 4.5 7.6 0.1 3.2 3 0 0 3 3 3 0 Large-conductance mechanosensitive channel, MscL Promethin PF16015.5 AAZ34041.1 - 1.1 9.2 8.0 0.2 11.6 0.9 2.5 2 0 0 2 2 2 0 Promethin DUF4064 PF13273.6 AAZ34041.1 - 1.7 9.0 11.1 34 4.8 8.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) ABC_trans_aux PF03886.13 AAZ34042.1 - 1.9e-37 128.3 6.4 2.3e-37 128.1 6.4 1.1 1 0 0 1 1 1 1 ABC-type transport auxiliary lipoprotein component OTCace PF00185.24 AAZ34043.1 - 5.4e-49 166.3 0.0 7.3e-49 165.8 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 AAZ34043.1 - 9e-46 155.6 0.0 1.4e-45 155.0 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain MCPsignal PF00015.21 AAZ34044.1 - 6.5e-42 143.2 23.2 6.5e-42 143.2 23.2 3.6 1 1 2 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain 4HB_MCP_1 PF12729.7 AAZ34044.1 - 1.5e-14 53.9 8.3 2.3e-14 53.3 0.0 3.9 3 2 1 4 4 4 1 Four helix bundle sensory module for signal transduction HAMP PF00672.25 AAZ34044.1 - 4.8e-14 52.5 14.3 9.1e-13 48.4 0.6 5.0 5 0 0 5 5 5 2 HAMP domain DUF948 PF06103.11 AAZ34044.1 - 0.012 15.8 25.5 0.063 13.5 1.1 4.8 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF948) Serine_rich PF08824.10 AAZ34044.1 - 0.015 15.3 3.4 0.015 15.3 3.4 3.2 2 1 1 3 3 3 0 Serine rich protein interaction domain Jiraiya PF15038.6 AAZ34044.1 - 0.024 14.1 0.9 3.7 7.0 0.5 2.7 2 0 0 2 2 2 0 Jiraiya BLOC1_2 PF10046.9 AAZ34044.1 - 0.56 10.5 15.6 3.1 8.2 0.9 4.4 3 2 2 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 OpuAC PF04069.12 AAZ34045.1 - 5.3e-68 229.4 0.1 6.2e-68 229.2 0.1 1.0 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system MarR_2 PF12802.7 AAZ34046.1 - 3e-12 46.2 1.6 3e-12 46.2 1.6 1.9 2 0 0 2 2 2 1 MarR family MarR PF01047.22 AAZ34046.1 - 9.2e-12 44.7 0.0 1.8e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_Crp_2 PF13545.6 AAZ34046.1 - 1.4e-06 28.2 0.2 3.5e-06 26.9 0.2 1.7 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_27 PF13463.6 AAZ34046.1 - 5e-06 26.9 0.1 9.4e-06 26.0 0.1 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_IclR PF09339.10 AAZ34046.1 - 6e-06 26.0 0.8 1.2e-05 24.9 0.8 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain TrmB PF01978.19 AAZ34046.1 - 3e-05 23.8 0.0 4.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 AAZ34046.1 - 5.7e-05 22.6 0.0 0.00011 21.7 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Rrf2 PF02082.20 AAZ34046.1 - 7.7e-05 23.0 0.1 0.00038 20.8 0.0 2.0 2 0 0 2 2 2 1 Transcriptional regulator GntR PF00392.21 AAZ34046.1 - 9.4e-05 22.0 0.3 0.00029 20.4 0.3 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family B-block_TFIIIC PF04182.12 AAZ34046.1 - 0.00022 21.3 0.0 0.00035 20.7 0.0 1.5 1 1 0 1 1 1 1 B-block binding subunit of TFIIIC HTH_36 PF13730.6 AAZ34046.1 - 0.0015 18.5 0.0 0.0029 17.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain LexA_DNA_bind PF01726.16 AAZ34046.1 - 0.0022 17.7 0.0 0.0041 16.9 0.0 1.4 1 0 0 1 1 1 1 LexA DNA binding domain HTH_5 PF01022.20 AAZ34046.1 - 0.014 15.2 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Fe_dep_repress PF01325.19 AAZ34046.1 - 0.022 15.0 0.0 0.04 14.1 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HxlR PF01638.17 AAZ34046.1 - 0.047 13.5 0.1 0.075 12.9 0.1 1.4 1 0 0 1 1 1 0 HxlR-like helix-turn-helix Unstab_antitox PF09720.10 AAZ34046.1 - 0.14 12.3 1.8 0.59 10.2 0.1 2.7 3 0 0 3 3 3 0 Putative addiction module component AAA_2 PF07724.14 AAZ34047.1 - 1e-49 169.0 0.0 1.8e-49 168.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) zf-C4_ClpX PF06689.13 AAZ34047.1 - 1.6e-20 72.7 4.2 4.4e-20 71.3 4.2 1.8 1 0 0 1 1 1 1 ClpX C4-type zinc finger AAA PF00004.29 AAZ34047.1 - 8.6e-16 58.6 0.0 4.2e-15 56.4 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 AAZ34047.1 - 2.9e-15 56.1 0.2 2.9e-15 56.1 0.2 2.4 3 0 0 3 3 3 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 AAZ34047.1 - 3.3e-07 30.4 0.0 6.7e-06 26.2 0.1 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 AAZ34047.1 - 2.1e-06 27.2 0.2 0.00018 21.0 0.1 3.0 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 AAZ34047.1 - 2.2e-06 28.0 0.1 1.7e-05 25.1 0.1 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 AAZ34047.1 - 8.6e-06 25.6 0.2 2.3e-05 24.2 0.2 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain MCM PF00493.23 AAZ34047.1 - 1.4e-05 24.3 0.1 2.3e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain AAA_18 PF13238.6 AAZ34047.1 - 0.00014 22.4 0.1 0.0038 17.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AAZ34047.1 - 0.00069 20.0 0.0 0.0017 18.8 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain Sigma54_activat PF00158.26 AAZ34047.1 - 0.00069 19.4 0.0 0.043 13.5 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_24 PF13479.6 AAZ34047.1 - 0.0016 18.2 0.1 0.0026 17.5 0.1 1.3 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 AAZ34047.1 - 0.0031 16.6 0.0 0.0051 15.9 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Sigma54_activ_2 PF14532.6 AAZ34047.1 - 0.0039 17.3 0.0 0.0089 16.1 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_14 PF13173.6 AAZ34047.1 - 0.0048 16.9 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 AAZ34047.1 - 0.0067 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 AAZ34047.1 - 0.0068 15.9 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 AAZ34047.1 - 0.01 15.1 0.1 0.026 13.7 0.0 1.6 1 1 0 1 1 1 0 TIP49 P-loop domain ABC_tran PF00005.27 AAZ34047.1 - 0.013 16.0 0.0 0.042 14.4 0.0 2.0 2 0 0 2 2 1 0 ABC transporter AAA_33 PF13671.6 AAZ34047.1 - 0.017 15.3 0.0 0.041 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 AAZ34047.1 - 0.02 14.7 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 AAZ34047.1 - 0.025 14.5 0.1 0.15 12.0 0.0 2.3 3 0 0 3 3 2 0 NACHT domain TsaE PF02367.17 AAZ34047.1 - 0.03 14.3 0.0 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 AAZ34047.1 - 0.035 13.9 0.0 0.078 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ResIII PF04851.15 AAZ34047.1 - 0.045 13.7 0.2 0.18 11.8 0.1 2.0 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit DUF1296 PF06972.11 AAZ34047.1 - 0.05 13.8 1.2 0.14 12.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) ATPase PF06745.13 AAZ34047.1 - 0.055 12.8 2.9 3.3 7.0 0.1 2.6 2 1 0 3 3 3 0 KaiC DEAD PF00270.29 AAZ34047.1 - 0.056 13.2 1.9 0.49 10.1 1.9 2.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_28 PF13521.6 AAZ34047.1 - 0.069 13.4 0.0 0.2 11.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_23 PF13476.6 AAZ34047.1 - 0.072 13.6 0.5 0.18 12.3 0.4 2.0 2 1 0 2 2 1 0 AAA domain AAA_8 PF12780.7 AAZ34047.1 - 0.08 12.3 0.0 0.45 9.8 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region D4 AAA_15 PF13175.6 AAZ34047.1 - 0.081 12.6 0.0 0.18 11.5 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.19 AAZ34047.1 - 0.085 12.3 0.0 0.2 11.1 0.0 1.6 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain PduV-EutP PF10662.9 AAZ34047.1 - 0.088 12.6 0.0 0.43 10.3 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PhoH PF02562.16 AAZ34047.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.22 AAZ34047.1 - 0.12 12.7 0.0 0.32 11.4 0.0 1.8 1 1 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 AAZ34047.1 - 0.17 12.2 0.1 4 7.8 0.1 2.5 2 1 1 3 3 2 0 AAA domain START PF01852.19 AAZ34048.1 - 0.0013 18.2 0.0 0.0015 18.0 0.0 1.1 1 0 0 1 1 1 1 START domain Polyketide_cyc PF03364.20 AAZ34048.1 - 0.0093 16.2 0.0 0.01 16.0 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 AAZ34048.1 - 0.069 13.4 0.0 0.072 13.4 0.0 1.0 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport CP_ATPgrasp_2 PF14403.6 AAZ34049.1 - 8.7e-161 535.0 0.0 1e-160 534.8 0.0 1.0 1 0 0 1 1 1 1 Circularly permuted ATP-grasp type 2 CP_ATPgrasp_1 PF04174.13 AAZ34049.1 - 3.9e-152 506.0 0.0 5.4e-152 505.6 0.0 1.2 1 0 0 1 1 1 1 A circularly permuted ATPgrasp SPOR PF05036.13 AAZ34049.1 - 0.059 13.7 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Sporulation related domain ATPgrasp_YheCD PF14398.6 AAZ34049.1 - 0.097 11.9 0.0 2.3 7.4 0.0 2.7 2 1 0 2 2 2 0 YheC/D like ATP-grasp DUF3617 PF12276.8 AAZ34050.1 - 8.1e-34 116.8 4.5 1.1e-33 116.4 4.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3617) CM_2 PF01817.21 AAZ34051.1 - 2.5e-10 40.5 0.8 4.5e-10 39.7 0.2 1.7 2 0 0 2 2 2 1 Chorismate mutase type II CheB_methylest PF01339.17 AAZ34052.1 - 4e-58 195.9 0.1 2.9e-57 193.1 0.0 2.1 2 0 0 2 2 2 1 CheB methylesterase Response_reg PF00072.24 AAZ34052.1 - 3.4e-22 78.7 0.1 6.7e-22 77.8 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain XPC-binding PF09280.11 AAZ34052.1 - 0.02 14.6 0.1 0.17 11.7 0.1 2.2 2 0 0 2 2 2 0 XPC-binding domain Stb3 PF10330.9 AAZ34052.1 - 0.05 13.6 0.1 0.2 11.7 0.0 1.9 2 0 0 2 2 2 0 Putative Sin3 binding protein Orn_Arg_deC_N PF02784.16 AAZ34053.1 - 5.8e-54 183.1 0.0 8.5e-54 182.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 AAZ34053.1 - 3e-12 46.6 0.0 5.3e-12 45.8 0.0 1.6 1 1 1 2 2 2 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain DUF962 PF06127.11 AAZ34054.1 - 1.8e-35 120.9 0.5 2e-35 120.8 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF962) MFS_1 PF07690.16 AAZ34055.1 - 2.6e-35 122.0 33.8 1.4e-19 70.2 18.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AAZ34055.1 - 1.7e-06 27.2 10.1 1.7e-06 27.2 10.1 2.5 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 AAZ34055.1 - 0.00015 20.8 5.7 0.00015 20.8 5.7 2.1 1 1 1 2 2 2 2 MFS_1 like family TMEM210 PF15195.6 AAZ34055.1 - 0.21 12.0 2.3 2.9 8.4 0.1 3.3 4 0 0 4 4 4 0 TMEM210 family BPD_transp_1 PF00528.22 AAZ34056.1 - 2.6e-17 63.2 14.3 2.6e-17 63.2 14.3 1.9 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component GntR PF00392.21 AAZ34057.1 - 2.4e-16 59.1 0.1 5.4e-16 58.0 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family FCD PF07729.12 AAZ34057.1 - 4.2e-15 56.3 6.8 4.2e-15 56.3 6.8 2.2 2 0 0 2 2 2 1 FCD domain HTH_24 PF13412.6 AAZ34057.1 - 0.00022 20.7 0.1 0.00073 19.1 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding TrmB PF01978.19 AAZ34057.1 - 0.00061 19.6 0.0 0.0086 15.9 0.0 2.4 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.6 AAZ34057.1 - 0.022 14.8 0.1 0.15 12.1 0.0 2.4 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain Fe_dep_repress PF01325.19 AAZ34057.1 - 0.027 14.6 0.0 0.074 13.3 0.0 1.6 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain PL48 PF15903.5 AAZ34057.1 - 0.03 13.3 1.9 0.049 12.6 1.9 1.3 1 0 0 1 1 1 0 Filopodia upregulated, FAM65 TFIIE_alpha PF02002.17 AAZ34057.1 - 0.062 13.2 0.0 2.5 8.0 0.0 2.5 2 0 0 2 2 2 0 TFIIE alpha subunit Rrf2 PF02082.20 AAZ34057.1 - 0.071 13.5 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator MarR_2 PF12802.7 AAZ34057.1 - 0.12 12.3 0.0 0.12 12.3 0.0 3.0 4 1 0 4 4 4 0 MarR family Kdo PF06293.14 AAZ34058.1 - 2.4e-18 66.3 0.1 3e-18 65.9 0.1 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 AAZ34058.1 - 0.00013 21.5 0.0 0.00019 20.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 AAZ34058.1 - 0.00014 21.5 0.0 0.0007 19.2 0.0 2.1 1 1 1 2 2 2 1 RIO1 family APH PF01636.23 AAZ34058.1 - 0.0014 18.6 3.7 0.005 16.8 3.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 AAZ34058.1 - 0.005 16.5 0.1 0.0083 15.7 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_Tyr PF07714.17 AAZ34058.1 - 0.0055 16.0 0.0 0.0066 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Asparaginase PF00710.20 AAZ34059.1 - 3.1e-43 147.6 0.0 4.4e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 AAZ34059.1 - 3.9e-25 88.3 0.0 6.6e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain DUF4124 PF13511.6 AAZ34060.1 - 1.2e-12 48.0 0.1 2.2e-12 47.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4124) BiPBP_C PF06832.12 AAZ34060.1 - 0.00074 19.5 0.0 0.0017 18.4 0.0 1.6 1 0 0 1 1 1 1 Penicillin-Binding Protein C-terminus Family SATase_N PF06426.14 AAZ34061.1 - 2e-21 76.3 1.1 3e-21 75.7 1.1 1.3 1 0 0 1 1 1 1 Serine acetyltransferase, N-terminal Hexapep PF00132.24 AAZ34061.1 - 9e-08 31.6 8.2 2.1e-06 27.2 1.1 3.0 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AAZ34061.1 - 0.025 14.3 1.6 0.025 14.3 1.6 2.9 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase CT_A_B PF02626.15 AAZ34062.1 - 1.1e-87 294.1 3.7 1.4e-87 293.7 3.3 1.4 2 0 0 2 2 2 1 Carboxyltransferase domain, subdomain A and B CT_C_D PF02682.16 AAZ34062.1 - 4e-62 209.6 0.0 8.8e-62 208.4 0.0 1.6 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D PEP_mutase PF13714.6 AAZ34063.1 - 1.7e-45 155.4 2.9 2e-45 155.1 2.9 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase NIL PF09383.10 AAZ34063.1 - 0.038 13.8 0.0 0.098 12.5 0.0 1.6 1 0 0 1 1 1 0 NIL domain LysR_substrate PF03466.20 AAZ34064.1 - 2.2e-19 69.7 0.1 3.1e-19 69.2 0.1 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ34064.1 - 1.8e-17 63.0 0.1 3.1e-17 62.3 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AAZ34064.1 - 0.0033 17.2 0.1 0.0078 16.0 0.1 1.7 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain NusG PF02357.19 AAZ34065.1 - 1.2e-28 99.4 0.1 2.1e-28 98.7 0.0 1.4 2 0 0 2 2 2 1 Transcription termination factor nusG KOW PF00467.29 AAZ34065.1 - 6.1e-09 35.5 0.1 1.1e-08 34.7 0.1 1.5 1 0 0 1 1 1 1 KOW motif Pilus_CpaD PF09476.10 AAZ34066.1 - 0.0028 17.4 0.5 0.014 15.1 0.0 2.0 1 1 1 2 2 2 1 Pilus biogenesis CpaD protein (pilus_cpaD) PAS_4 PF08448.10 AAZ34067.1 - 5.5e-22 78.1 0.0 1.6e-19 70.2 0.0 2.9 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 AAZ34067.1 - 2.7e-20 72.4 0.0 2.4e-17 63.0 0.0 2.6 2 0 0 2 2 2 2 PAS fold HATPase_c PF02518.26 AAZ34067.1 - 1e-18 67.9 0.0 1.8e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AAZ34067.1 - 2.9e-15 56.4 0.1 9.6e-15 54.7 0.0 2.0 2 0 0 2 2 2 1 Response regulator receiver domain PAS PF00989.25 AAZ34067.1 - 2.4e-12 46.9 0.0 1.6e-07 31.3 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 AAZ34067.1 - 1.9e-09 37.7 0.0 8.7e-07 29.1 0.0 2.7 2 1 0 2 2 2 1 PAS domain HisKA PF00512.25 AAZ34067.1 - 4.4e-08 33.1 1.1 1.2e-07 31.6 0.1 2.4 2 0 0 2 2 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 AAZ34067.1 - 0.0022 17.8 0.0 0.0063 16.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HPTransfase PF10090.9 AAZ34067.1 - 0.0059 16.4 0.1 0.024 14.4 0.0 2.0 2 0 0 2 2 2 1 Histidine phosphotransferase C-terminal domain RNase_E_G PF10150.9 AAZ34067.1 - 0.0081 15.6 0.0 0.055 12.9 0.0 2.2 2 1 0 2 2 2 1 Ribonuclease E/G family BcrAD_BadFG PF01869.20 AAZ34067.1 - 0.051 13.1 0.0 0.074 12.5 0.0 1.4 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family FeoB_Cyto PF17910.1 AAZ34067.1 - 0.1 13.2 0.5 0.38 11.3 0.3 2.1 2 0 0 2 2 2 0 FeoB cytosolic helical domain YceD PF02620.17 AAZ34068.1 - 5.6e-18 65.2 0.8 8.1e-18 64.7 0.8 1.3 1 0 0 1 1 1 1 Large ribosomal RNA subunit accumulation protein YceD ADH_N PF08240.12 AAZ34069.1 - 3.9e-29 100.7 0.1 7.6e-29 99.8 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.6 AAZ34069.1 - 5.8e-12 45.3 0.0 1.4e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.26 AAZ34069.1 - 1.3e-09 38.1 1.1 3.6e-08 33.4 0.1 2.3 1 1 1 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 AAZ34069.1 - 0.004 16.5 0.2 0.0067 15.7 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ATPgrasp_N PF18130.1 AAZ34069.1 - 0.059 13.9 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp N-terminal domain FAD_binding_3 PF01494.19 AAZ34069.1 - 0.11 11.8 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Glu_dehyd_C PF16912.5 AAZ34069.1 - 0.21 11.1 1.2 1.6 8.1 0.1 2.9 3 1 1 4 4 4 0 Glucose dehydrogenase C-terminus Bac_DnaA PF00308.18 AAZ34070.1 - 1e-20 74.6 0.0 1.1e-19 71.2 0.0 1.9 1 1 0 1 1 1 1 Bacterial dnaA protein AAA PF00004.29 AAZ34070.1 - 0.0015 18.9 0.0 0.013 15.9 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AAZ34070.1 - 0.011 16.1 0.8 1.2 9.4 0.8 3.0 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 AAZ34070.1 - 0.051 13.3 0.3 2.9 7.6 0.0 2.8 1 1 1 2 2 2 0 IstB-like ATP binding protein RNA_helicase PF00910.22 AAZ34070.1 - 0.22 11.9 0.0 0.48 10.8 0.0 1.5 1 1 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 AAZ34070.1 - 0.22 11.4 0.0 0.43 10.5 0.0 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea TetR_N PF00440.23 AAZ34071.1 - 6.8e-11 41.8 0.1 1.2e-10 41.0 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.6 AAZ34071.1 - 1.3e-07 31.9 0.4 2.4e-07 31.0 0.4 1.6 1 1 0 1 1 1 1 BetI-type transcriptional repressor, C-terminal TetR_C_2 PF08361.11 AAZ34071.1 - 0.07 13.2 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 MAATS-type transcriptional repressor, C-terminal region TetR_C_17 PF17922.1 AAZ34071.1 - 0.1 12.7 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain HATPase_c PF02518.26 AAZ34072.1 - 2.4e-19 69.9 0.0 3.7e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAZ34072.1 - 3.6e-10 39.7 2.4 7.8e-10 38.6 0.8 2.2 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AAZ34072.1 - 1.4e-07 31.7 0.1 5.5e-07 29.9 0.0 2.1 2 0 0 2 2 2 1 HAMP domain DUF4347 PF14252.6 AAZ34072.1 - 0.076 12.9 0.2 0.17 11.7 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4347) DUF4307 PF14155.6 AAZ34072.1 - 0.087 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) Peptidase_M75 PF09375.10 AAZ34073.1 - 3.8e-35 121.7 11.1 4.8e-35 121.4 11.1 1.1 1 0 0 1 1 1 1 Imelysin Cupredoxin_1 PF13473.6 AAZ34073.1 - 2.7e-16 59.5 0.0 4.3e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Cupredoxin-like domain Aminotran_5 PF00266.19 AAZ34074.1 - 3.6e-71 240.1 0.2 4.8e-71 239.7 0.2 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 AAZ34074.1 - 0.0053 15.3 0.0 0.0082 14.7 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 AAZ34074.1 - 0.018 14.4 0.2 0.038 13.3 0.2 1.5 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 AAZ34074.1 - 0.065 12.5 0.2 0.083 12.2 0.2 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase ACT_6 PF13740.6 AAZ34075.1 - 4.1e-19 68.3 0.0 5.6e-18 64.7 0.1 2.1 2 1 0 2 2 2 1 ACT domain DUF4745 PF15923.5 AAZ34075.1 - 0.0077 16.2 0.1 0.022 14.8 0.1 1.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4745) Sigma70_r2 PF04542.14 AAZ34076.1 - 8.7e-20 70.3 0.1 1.5e-19 69.5 0.1 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 AAZ34076.1 - 7.2e-12 44.6 0.0 1.3e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 AAZ34076.1 - 7.7e-09 35.1 0.0 1.7e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 AAZ34076.1 - 0.0041 17.0 0.6 0.0077 16.1 0.6 1.4 1 1 0 1 1 1 1 ECF sigma factor ABC_tran PF00005.27 AAZ34077.1 - 1.3e-50 171.5 0.0 8.8e-29 100.8 0.0 2.2 2 0 0 2 2 2 2 ABC transporter oligo_HPY PF08352.12 AAZ34077.1 - 2.5e-13 50.3 0.2 2e-10 41.0 0.1 2.5 2 0 0 2 2 2 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 AAZ34077.1 - 1.2e-11 45.0 2.8 0.011 15.5 0.0 4.1 2 2 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AAZ34077.1 - 5.4e-09 36.7 1.2 0.0013 19.2 0.2 2.6 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 AAZ34077.1 - 8.9e-09 35.1 0.1 5.7e-05 22.6 0.0 3.2 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAZ34077.1 - 7.3e-08 32.0 0.9 0.0069 16.1 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 AAZ34077.1 - 7.5e-08 32.7 0.9 0.0042 17.4 0.0 2.9 3 1 0 3 3 2 2 AAA domain AAA PF00004.29 AAZ34077.1 - 8.4e-07 29.5 0.1 0.02 15.3 0.0 3.2 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 AAZ34077.1 - 2.1e-05 25.1 0.0 0.1 13.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 AAZ34077.1 - 7.5e-05 22.5 0.1 0.052 13.3 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein RsgA_GTPase PF03193.16 AAZ34077.1 - 7.6e-05 22.7 0.8 0.41 10.5 0.1 2.7 3 0 0 3 3 3 2 RsgA GTPase AAA_25 PF13481.6 AAZ34077.1 - 0.0001 22.0 7.0 0.019 14.5 2.7 3.6 2 2 0 2 2 2 1 AAA domain AAA_24 PF13479.6 AAZ34077.1 - 0.00013 21.7 0.1 0.39 10.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 AAZ34077.1 - 0.00022 21.4 0.6 0.66 10.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain CbiA PF01656.23 AAZ34077.1 - 0.00027 21.0 0.1 0.097 12.7 0.0 2.4 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain PRK PF00485.18 AAZ34077.1 - 0.00053 19.8 2.2 1 9.0 0.2 3.5 4 0 0 4 4 3 1 Phosphoribulokinase / Uridine kinase family Sigma54_activat PF00158.26 AAZ34077.1 - 0.00085 19.1 0.1 0.6 9.8 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.12 AAZ34077.1 - 0.00096 19.1 4.7 0.69 9.8 0.1 3.5 4 0 0 4 4 4 2 NACHT domain AAA_5 PF07728.14 AAZ34077.1 - 0.0012 18.8 1.9 1.6 8.7 0.1 3.2 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.25 AAZ34077.1 - 0.0024 17.5 0.0 1.7 8.2 0.0 2.3 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.6 AAZ34077.1 - 0.0025 17.5 1.2 1.2 8.8 0.5 2.7 2 1 0 2 2 2 1 AAA domain PhoH PF02562.16 AAZ34077.1 - 0.0026 17.3 0.8 0.49 9.8 0.2 2.3 2 0 0 2 2 2 1 PhoH-like protein Zeta_toxin PF06414.12 AAZ34077.1 - 0.0026 17.0 0.2 2 7.6 0.1 2.5 2 0 0 2 2 2 2 Zeta toxin APS_kinase PF01583.20 AAZ34077.1 - 0.0038 17.1 0.8 2.7 7.9 0.1 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_23 PF13476.6 AAZ34077.1 - 0.0039 17.7 0.2 1.3 9.5 0.1 2.3 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 AAZ34077.1 - 0.004 16.6 0.1 1.1 8.6 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 AAZ34077.1 - 0.0067 15.6 1.6 2.4 7.3 0.0 2.5 3 0 0 3 3 2 2 NB-ARC domain DUF87 PF01935.17 AAZ34077.1 - 0.0072 16.4 0.6 0.45 10.6 0.0 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain ATPase PF06745.13 AAZ34077.1 - 0.0089 15.4 2.9 2.7 7.3 0.1 3.0 4 0 0 4 4 3 2 KaiC AAA_7 PF12775.7 AAZ34077.1 - 0.012 15.2 0.2 6.1 6.3 0.0 2.6 3 0 0 3 3 2 0 P-loop containing dynein motor region MMR_HSR1 PF01926.23 AAZ34077.1 - 0.018 15.1 0.2 2.8 8.0 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase TsaE PF02367.17 AAZ34077.1 - 0.02 14.9 0.4 2.8 7.9 0.1 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MobB PF03205.14 AAZ34077.1 - 0.021 14.7 0.2 1.7 8.5 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_15 PF13175.6 AAZ34077.1 - 0.024 14.4 0.0 2.5 7.7 0.2 2.3 2 0 0 2 2 2 0 AAA ATPase domain NTPase_1 PF03266.15 AAZ34077.1 - 0.032 14.1 0.7 9.2 6.2 0.2 2.7 3 0 0 3 3 2 0 NTPase Roc PF08477.13 AAZ34077.1 - 0.034 14.4 0.4 5.7 7.2 0.1 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_11 PF13086.6 AAZ34077.1 - 0.037 13.8 0.2 0.25 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 AAZ34077.1 - 0.059 13.1 0.3 8.9 6.0 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CPT PF07931.12 AAZ34077.1 - 0.068 13.0 0.6 10 6.0 0.1 2.7 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein DUF3987 PF13148.6 AAZ34077.1 - 0.082 11.9 0.3 0.75 8.7 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) RecA PF00154.21 AAZ34077.1 - 0.086 12.3 0.3 0.97 8.8 0.1 2.2 2 0 0 2 2 2 0 recA bacterial DNA recombination protein G-alpha PF00503.20 AAZ34077.1 - 0.11 11.6 0.0 11 5.1 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit RNA_helicase PF00910.22 AAZ34077.1 - 0.12 12.8 0.3 9.8 6.6 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Pox_A32 PF04665.12 AAZ34077.1 - 0.16 11.4 1.2 0.7 9.3 0.1 2.1 2 0 0 2 2 2 0 Poxvirus A32 protein TIP49 PF06068.13 AAZ34077.1 - 0.18 11.0 1.0 4.8 6.3 0.2 2.3 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_19 PF13245.6 AAZ34077.1 - 0.18 12.2 0.5 10 6.5 0.3 2.6 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 AAZ34077.1 - 1.3 9.2 3.6 31 4.7 0.3 3.1 3 0 0 3 3 3 0 AAA domain HATPase_c PF02518.26 AAZ34078.1 - 3.2e-17 63.0 0.0 5.4e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.26 AAZ34078.1 - 2.6e-07 31.4 0.1 5.4e-07 30.3 0.1 1.6 1 0 0 1 1 1 1 GAF domain HisKA PF00512.25 AAZ34078.1 - 0.0002 21.3 0.9 0.0002 21.3 0.9 2.3 1 1 1 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 AAZ34078.1 - 0.0094 15.8 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Proteasome PF00227.26 AAZ34078.1 - 0.18 11.3 0.1 0.52 9.8 0.0 1.7 1 1 1 2 2 2 0 Proteasome subunit IstB_IS21 PF01695.17 AAZ34080.1 - 5.6e-62 208.6 0.1 8.3e-62 208.1 0.1 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein Bac_DnaA PF00308.18 AAZ34080.1 - 2.4e-06 27.5 0.0 3.4e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial dnaA protein AAA_28 PF13521.6 AAZ34080.1 - 4.2e-05 23.9 0.0 0.0002 21.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 AAZ34080.1 - 0.0013 18.2 0.1 0.0053 16.2 0.0 1.9 2 0 0 2 2 2 1 PhoH-like protein AAA PF00004.29 AAZ34080.1 - 0.0025 18.2 0.0 0.0047 17.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 AAZ34080.1 - 0.0041 16.9 0.0 0.0064 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 AAZ34080.1 - 0.017 15.5 0.1 0.046 14.1 0.1 1.8 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 AAZ34080.1 - 0.023 14.1 0.0 0.041 13.2 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.6 AAZ34080.1 - 0.025 15.0 0.1 0.05 14.0 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain A_deamin PF02137.18 AAZ34080.1 - 0.039 13.4 0.0 0.067 12.6 0.0 1.3 1 0 0 1 1 1 0 Adenosine-deaminase (editase) domain Parvo_NS1 PF01057.17 AAZ34080.1 - 0.043 12.9 0.2 1.4 7.9 0.0 2.3 1 1 1 2 2 2 0 Parvovirus non-structural protein NS1 FtsK_SpoIIIE PF01580.18 AAZ34080.1 - 0.044 13.1 0.0 0.078 12.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Mg_chelatase PF01078.21 AAZ34080.1 - 0.052 12.9 0.0 0.13 11.6 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 AAZ34080.1 - 0.06 13.6 0.4 0.37 11.1 0.1 2.3 2 1 1 3 3 3 0 AAA domain AAA_33 PF13671.6 AAZ34080.1 - 0.073 13.2 1.6 0.27 11.4 1.6 2.1 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AAZ34080.1 - 0.076 12.7 0.0 0.2 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 AAZ34080.1 - 0.096 12.2 0.0 0.44 10.0 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region GDP_Man_Dehyd PF16363.5 AAZ34081.1 - 6.4e-44 150.7 0.0 9.5e-43 146.8 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 AAZ34081.1 - 1.9e-38 132.3 0.0 2.4e-38 132.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 AAZ34081.1 - 2.4e-15 56.4 0.0 3e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 AAZ34081.1 - 3.2e-09 36.3 0.1 4e-08 32.8 0.0 2.3 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 AAZ34081.1 - 3.3e-08 32.9 0.0 7.4e-08 31.7 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 AAZ34081.1 - 0.0039 16.4 0.0 0.0064 15.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Glyco_transf_4 PF13439.6 AAZ34081.1 - 0.016 15.2 0.1 0.08 12.9 0.1 1.9 1 1 0 1 1 1 0 Glycosyltransferase Family 4 adh_short PF00106.25 AAZ34081.1 - 0.2 11.1 1.3 0.51 9.8 0.1 2.4 3 1 0 3 3 3 0 short chain dehydrogenase DUF3100 PF11299.8 AAZ34082.1 - 1.4e-90 302.8 24.8 1.8e-89 299.2 16.9 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3100) Aminotran_4 PF01063.19 AAZ34083.1 - 6.2e-49 166.9 0.0 7.1e-49 166.7 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV Response_reg PF00072.24 AAZ34084.1 - 1.6e-26 92.7 0.0 2.5e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAZ34084.1 - 1.4e-18 66.7 0.0 2.6e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal FleQ PF06490.11 AAZ34084.1 - 0.073 13.4 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ DUF2390 PF09523.10 AAZ34085.1 - 5e-31 107.2 3.0 5e-31 107.2 3.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2390) Metallophos_2 PF12850.7 AAZ34086.1 - 1.7e-14 54.3 0.3 1.3e-13 51.5 0.3 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 AAZ34086.1 - 2.3e-11 44.6 2.6 3.2e-11 44.1 2.6 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ISN1 PF06437.11 AAZ34086.1 - 0.035 13.0 0.0 0.05 12.5 0.0 1.2 1 0 0 1 1 1 0 IMP-specific 5'-nucleotidase Fer4_18 PF13746.6 AAZ34086.1 - 0.14 12.3 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain SecA_DEAD PF07517.14 AAZ34088.1 - 5.7e-132 439.4 1.3 1.1e-131 438.4 1.3 1.5 1 0 0 1 1 1 1 SecA DEAD-like domain SecA_SW PF07516.13 AAZ34088.1 - 7e-68 228.6 6.0 7e-68 228.6 6.0 2.1 2 0 0 2 2 2 1 SecA Wing and Scaffold domain SecA_PP_bind PF01043.20 AAZ34088.1 - 6.3e-34 117.0 0.7 2.1e-33 115.3 0.1 2.3 2 0 0 2 2 2 1 SecA preprotein cross-linking domain SEC-C PF02810.15 AAZ34088.1 - 2e-10 40.4 5.1 3.2e-10 39.7 5.1 1.4 1 0 0 1 1 1 1 SEC-C motif DEAD PF00270.29 AAZ34088.1 - 0.0043 16.8 0.0 0.031 14.0 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AAZ34088.1 - 0.022 15.1 4.4 0.13 12.6 0.0 3.0 3 0 0 3 3 3 0 Helicase conserved C-terminal domain SBP_bac_11 PF13531.6 AAZ34089.1 - 1.6e-32 113.2 1.2 1.8e-32 113.0 1.2 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AAZ34089.1 - 1.5e-07 31.7 1.0 0.00028 20.9 0.2 2.2 1 1 1 2 2 2 2 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 AAZ34089.1 - 6.4e-05 22.9 0.4 0.097 12.5 0.1 2.1 1 1 0 2 2 2 2 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AAZ34089.1 - 0.011 15.2 0.0 0.037 13.4 0.0 1.8 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein Chalcone PF02431.15 AAZ34089.1 - 0.07 12.5 0.0 0.14 11.6 0.0 1.4 2 0 0 2 2 2 0 Chalcone-flavanone isomerase Aldedh PF00171.22 AAZ34090.1 - 2.9e-141 471.1 0.0 3.3e-141 471.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 AAZ34090.1 - 0.012 14.7 0.0 0.033 13.3 0.0 1.7 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) Wtap PF17098.5 AAZ34090.1 - 0.18 11.8 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 WTAP/Mum2p family NTP_transf_3 PF12804.7 AAZ34091.1 - 3.1e-10 40.7 0.0 3.6e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 AAZ34091.1 - 4.4e-08 33.0 0.0 5.9e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase DUF432 PF04254.13 AAZ34091.1 - 0.011 15.9 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF432) IspD PF01128.19 AAZ34091.1 - 0.12 12.2 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase SBF PF01758.16 AAZ34092.1 - 0.013 15.1 1.1 0.18 11.4 0.4 2.1 2 0 0 2 2 2 0 Sodium Bile acid symporter family RHS_repeat PF05593.14 AAZ34092.1 - 0.17 12.5 2.2 0.2 12.2 0.4 2.1 3 0 0 3 3 3 0 RHS Repeat DDE_Tnp_1_6 PF13751.6 AAZ34093.1 - 2.8e-17 63.1 4.8 4.6e-17 62.4 4.8 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 AAZ34093.1 - 2.2e-11 43.8 0.0 6.1e-11 42.4 0.0 1.7 1 1 0 1 1 1 1 Transposase DDE domain ArgoMid PF16487.5 AAZ34093.1 - 0.072 13.4 0.3 0.19 12.0 0.1 1.8 2 0 0 2 2 2 0 Mid domain of argonaute Ig_3 PF13927.6 AAZ34093.1 - 0.095 13.3 0.2 5.3 7.7 0.1 2.4 2 0 0 2 2 2 0 Immunoglobulin domain HTH_12 PF08461.10 AAZ34093.1 - 0.11 12.4 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain Amidohydro_3 PF07969.11 AAZ34094.1 - 5e-59 201.0 1.2 6.1e-59 200.7 1.2 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 AAZ34094.1 - 6.1e-07 29.1 0.2 0.014 14.7 0.9 2.9 2 1 0 2 2 2 2 Amidohydrolase family Urease_alpha PF00449.20 AAZ34094.1 - 0.00082 19.7 0.4 0.0017 18.6 0.4 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain DUF934 PF06073.12 AAZ34095.1 - 2.9e-45 152.6 0.1 3.6e-45 152.2 0.1 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF934) BPD_transp_2 PF02653.16 AAZ34096.1 - 4.2e-32 111.4 23.9 6.2e-32 110.8 23.9 1.3 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component DUF2061 PF09834.9 AAZ34096.1 - 0.073 13.6 0.8 0.39 11.3 0.8 2.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2061) DUF1294 PF06961.13 AAZ34096.1 - 1.1 9.5 6.3 21 5.5 0.3 4.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1294) HAD_2 PF13419.6 AAZ34097.1 - 4.6e-25 88.7 0.0 6.1e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAZ34097.1 - 3e-18 66.9 0.1 6.1e-18 65.9 0.1 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AAZ34097.1 - 1.8e-11 43.9 0.0 3.3e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 AAZ34097.1 - 9.6e-10 39.2 0.0 1.3e-09 38.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AAZ34097.1 - 0.0017 18.4 0.2 0.065 13.4 0.2 2.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF4032 PF13224.6 AAZ34097.1 - 0.13 12.1 0.1 0.27 11.1 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4032) VipB PF05943.12 AAZ34098.1 - 6.9e-196 651.0 0.0 8e-196 650.8 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion protein, EvpB/VC_A0108, tail sheath TssC PF17541.2 AAZ34098.1 - 0.0028 16.5 1.5 0.0052 15.7 1.5 1.3 1 0 0 1 1 1 1 Type VI secretion system, TssC, VipB CIDR1_gamma PF18562.1 AAZ34098.1 - 0.27 11.3 1.2 0.58 10.3 0.1 2.2 3 0 0 3 3 3 0 Cysteine-Rich Interdomain Region 1 gamma AMP-binding PF00501.28 AAZ34099.1 - 1.1e-85 287.8 0.1 1.4e-85 287.4 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAZ34099.1 - 3.2e-17 63.2 0.0 6.2e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HATPase_c PF02518.26 AAZ34100.1 - 6.2e-18 65.3 0.0 1.3e-17 64.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAZ34100.1 - 5.9e-12 45.5 1.1 2e-11 43.8 0.6 2.3 1 1 1 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AAZ34100.1 - 4.6e-11 42.9 5.4 8.6e-11 42.0 1.4 2.8 2 0 0 2 2 2 1 HAMP domain HATPase_c_2 PF13581.6 AAZ34100.1 - 0.00057 19.8 0.0 0.0022 17.9 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_5 PF14501.6 AAZ34100.1 - 0.0059 16.5 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 GHKL domain DUF4386 PF14329.6 AAZ34100.1 - 0.035 14.0 3.2 3.4 7.5 1.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4386) TPM_phosphatase PF04536.14 AAZ34100.1 - 0.12 12.6 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 TPM domain Usher PF00577.20 AAZ34101.1 - 6e-159 530.4 11.2 7.9e-159 530.0 11.2 1.1 1 0 0 1 1 1 1 Outer membrane usher protein PapC_N PF13954.6 AAZ34101.1 - 1.2e-36 125.9 0.0 2.1e-36 125.1 0.0 1.5 1 0 0 1 1 1 1 PapC N-terminal domain PapC_C PF13953.6 AAZ34101.1 - 1.1e-17 63.6 2.6 1.3e-17 63.4 0.1 2.4 3 0 0 3 3 3 1 PapC C-terminal domain DUF1652 PF07865.11 AAZ34102.1 - 7.9e-28 96.1 0.0 9.4e-28 95.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1652) Metalloenzyme PF01676.18 AAZ34103.1 - 6.6e-87 291.0 0.1 7.5e-87 290.8 0.1 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.13 AAZ34103.1 - 1.5e-78 263.2 0.3 2e-78 262.7 0.3 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.22 AAZ34103.1 - 0.0055 16.3 0.0 0.015 14.9 0.0 1.7 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 AAZ34103.1 - 0.011 15.2 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 Sulfatase PIG-L PF02585.17 AAZ34103.1 - 0.11 13.2 0.1 1.5 9.4 0.1 2.7 1 1 0 1 1 1 0 GlcNAc-PI de-N-acetylase PglZ PF08665.12 AAZ34103.1 - 0.2 11.7 0.3 0.51 10.4 0.2 1.7 2 0 0 2 2 2 0 PglZ domain Nitroreductase PF00881.24 AAZ34104.1 - 1.3e-15 57.8 0.0 1.6e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family AstE_AspA PF04952.14 AAZ34106.1 - 4.5e-25 88.3 0.0 2.3e-23 82.7 0.0 2.1 1 1 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Peptidase_M14 PF00246.24 AAZ34106.1 - 0.00013 21.9 0.0 0.00021 21.2 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase DAO PF01266.24 AAZ34107.1 - 1.5e-65 222.1 5.9 1.7e-65 221.9 5.9 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AAZ34107.1 - 3.1e-05 24.1 0.4 9.5e-05 22.6 0.4 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 AAZ34107.1 - 9.3e-05 21.7 4.1 0.00024 20.3 4.0 1.8 1 1 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 AAZ34107.1 - 0.00029 20.2 0.1 0.0084 15.4 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 AAZ34107.1 - 0.00045 19.7 1.3 0.0016 17.9 1.3 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 AAZ34107.1 - 0.0015 17.7 0.8 0.0022 17.1 0.8 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 AAZ34107.1 - 0.0025 17.1 0.0 1.2 8.3 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 AAZ34107.1 - 0.0038 16.5 0.1 0.0038 16.5 0.1 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 AAZ34107.1 - 0.0056 15.9 0.0 0.017 14.4 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAZ34107.1 - 0.01 16.4 0.1 0.036 14.6 0.3 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AAZ34107.1 - 0.015 14.0 0.1 0.13 10.9 0.5 1.9 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.14 AAZ34107.1 - 0.12 11.2 0.0 1.2 7.9 0.3 2.0 2 0 0 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.18 AAZ34107.1 - 0.24 11.2 0.1 0.42 10.5 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1883 PF08980.10 AAZ34109.1 - 5.2e-31 106.4 0.0 7.3e-31 106.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1883) ArsC PF03960.15 AAZ34110.1 - 1.9e-16 59.8 0.0 2e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 ArsC family Phage_term_sma PF07141.11 AAZ34110.1 - 0.068 12.9 0.8 1.5 8.6 0.1 2.0 1 1 1 2 2 2 0 Putative bacteriophage terminase small subunit DUF3110 PF11360.8 AAZ34110.1 - 0.085 13.1 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3110) Glutaredoxin PF00462.24 AAZ34110.1 - 0.2 11.9 0.0 0.29 11.4 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin BES1_N PF05687.13 AAZ34110.1 - 0.21 11.9 0.0 0.26 11.7 0.0 1.1 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal TerB PF05099.13 AAZ34111.1 - 1.2e-12 48.0 0.0 2e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TerB DnaJ PF00226.31 AAZ34111.1 - 7.9e-08 32.3 0.0 1.5e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain ThiW PF09512.10 AAZ34111.1 - 0.027 14.6 0.2 0.041 14.0 0.2 1.2 1 0 0 1 1 1 0 Thiamine-precursor transporter protein (ThiW) Rick_17kDa_Anti PF05433.15 AAZ34111.1 - 1.7 8.6 9.8 9.8 6.1 0.1 2.7 2 1 1 3 3 3 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 AAZ34111.1 - 1.9 8.6 7.2 7.7 6.6 7.2 1.9 1 1 0 1 1 1 0 Glycine zipper Gly-zipper_YMGG PF13441.6 AAZ34111.1 - 4.3 7.2 7.3 45 3.9 7.8 2.2 1 1 0 1 1 1 0 YMGG-like Gly-zipper PHY PF00360.20 AAZ34112.1 - 1.1e-38 132.4 0.0 2.3e-38 131.3 0.0 1.5 1 0 0 1 1 1 1 Phytochrome region PAS_2 PF08446.11 AAZ34112.1 - 1.2e-24 87.1 0.2 5e-24 85.0 0.1 2.2 2 0 0 2 2 2 1 PAS fold HATPase_c PF02518.26 AAZ34112.1 - 1.9e-24 86.3 0.0 3.7e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.26 AAZ34112.1 - 2.7e-19 70.1 0.1 1.1e-18 68.1 0.0 2.1 2 0 0 2 2 2 1 GAF domain HisKA PF00512.25 AAZ34112.1 - 1.5e-15 57.0 0.8 2.9e-14 52.8 0.1 2.8 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 AAZ34112.1 - 0.037 14.0 0.0 0.093 12.7 0.0 1.7 1 1 0 1 1 1 0 Histidine kinase-like ATPase domain His_Phos_1 PF00300.22 AAZ34113.1 - 6.4e-13 48.8 0.4 2.3e-11 43.8 0.2 2.0 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) GFO_IDH_MocA PF01408.22 AAZ34114.1 - 1.2e-21 77.8 0.0 1.8e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold AAA_21 PF13304.6 AAZ34115.1 - 1.3e-17 64.6 0.0 3.9e-16 59.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AAZ34115.1 - 1.1e-13 51.7 0.0 8.2e-06 25.8 0.0 2.1 1 1 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 AAZ34115.1 - 7.2e-10 38.7 0.0 2.5e-08 33.7 0.0 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AAZ34115.1 - 3.2e-06 27.8 0.0 6.4e-06 26.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 AAZ34115.1 - 0.00046 20.7 0.1 0.0023 18.5 0.0 2.2 2 1 0 2 2 2 1 ABC transporter AAA_13 PF13166.6 AAZ34115.1 - 0.0023 16.7 0.0 0.082 11.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AAZ34115.1 - 0.05 14.0 0.0 0.19 12.1 0.0 2.0 2 1 1 3 3 3 0 AAA ATPase domain Bac_DnaA PF00308.18 AAZ34115.1 - 0.067 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_22 PF13401.6 AAZ34115.1 - 0.096 13.0 0.1 0.44 10.8 0.1 2.2 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 AAZ34115.1 - 0.097 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain BPD_transp_1 PF00528.22 AAZ34116.1 - 4.2e-16 59.2 19.0 6.2e-16 58.7 13.9 2.1 2 0 0 2 2 2 2 Binding-protein-dependent transport system inner membrane component Bac_luciferase PF00296.20 AAZ34117.1 - 4.8e-58 197.1 0.2 5.3e-58 196.9 0.2 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase 2OG-Fe_Oxy_2 PF10014.9 AAZ34118.1 - 6.4e-34 117.4 0.1 7.8e-34 117.1 0.1 1.1 1 0 0 1 1 1 1 2OG-Fe dioxygenase LysR_substrate PF03466.20 AAZ34119.1 - 8.9e-36 123.2 0.7 8.9e-36 123.2 0.7 1.4 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ34119.1 - 4.7e-19 68.1 3.8 9.5e-19 67.1 3.8 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_34 PF13601.6 AAZ34119.1 - 0.16 12.2 0.0 0.37 11.0 0.0 1.7 1 0 0 1 1 1 0 Winged helix DNA-binding domain Hexapep PF00132.24 AAZ34120.1 - 2.1e-17 62.1 10.7 3.1e-08 33.0 3.7 4.3 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AAZ34120.1 - 6e-05 22.7 13.8 0.067 13.0 7.1 4.2 3 1 1 4 4 4 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 AAZ34120.1 - 0.13 11.2 0.2 0.32 9.9 0.2 1.8 1 1 0 1 1 1 0 L-fucokinase AP_endonuc_2 PF01261.24 AAZ34121.1 - 4.7e-05 22.9 0.8 7.2e-05 22.3 0.8 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Ldh_2 PF02615.14 AAZ34122.1 - 3.8e-107 358.3 0.2 4.2e-107 358.2 0.2 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Fer2 PF00111.27 AAZ34123.1 - 4.6e-15 55.3 0.7 8.2e-15 54.5 0.7 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.21 AAZ34123.1 - 2.1e-09 38.0 0.0 4.7e-09 36.9 0.0 1.6 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 AAZ34123.1 - 0.00014 22.1 0.0 0.00027 21.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain DUF2523 PF10734.9 AAZ34124.1 - 0.076 13.6 7.8 0.79 10.3 1.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2523) EMP70 PF02990.16 AAZ34124.1 - 0.12 11.0 2.8 0.13 10.9 2.8 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 Ycf4 PF02392.16 AAZ34124.1 - 0.73 9.4 2.3 1.3 8.5 2.3 1.3 1 0 0 1 1 1 0 Ycf4 SAM_MT PF04445.13 AAZ34125.1 - 7.4e-93 310.2 0.0 8.7e-93 310.0 0.0 1.0 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase CheR PF01739.18 AAZ34126.1 - 6.5e-36 123.7 0.0 8.8e-36 123.2 0.0 1.1 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain CheR_N PF03705.15 AAZ34126.1 - 2.1e-09 37.0 0.5 2.1e-09 37.0 0.5 1.8 2 0 0 2 2 2 1 CheR methyltransferase, all-alpha domain Queuosine_synth PF02547.15 AAZ34127.1 - 2.5e-135 450.8 0.0 2.9e-135 450.6 0.0 1.0 1 0 0 1 1 1 1 Queuosine biosynthesis protein Rx_N PF18052.1 AAZ34128.1 - 0.053 13.8 0.5 0.13 12.5 0.2 1.7 1 1 0 1 1 1 0 Rx N-terminal domain tRNA_U5-meth_tr PF05958.11 AAZ34129.1 - 9.3e-28 97.2 0.0 2.6e-26 92.5 0.0 2.6 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 AAZ34129.1 - 2.9e-08 33.6 0.0 4.9e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TRAM PF01938.20 AAZ34129.1 - 6.7e-08 32.4 0.1 1.4e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 TRAM domain Methyltransf_25 PF13649.6 AAZ34129.1 - 3.5e-06 27.6 0.0 9.7e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AAZ34129.1 - 0.00011 21.8 0.0 0.00018 21.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltr_RsmB-F PF01189.17 AAZ34129.1 - 0.00046 19.9 0.0 0.00083 19.0 0.0 1.5 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F RrnaAD PF00398.20 AAZ34129.1 - 0.002 17.3 0.0 0.0029 16.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Cons_hypoth95 PF03602.15 AAZ34129.1 - 0.0023 17.6 0.0 0.0041 16.8 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PCMT PF01135.19 AAZ34129.1 - 0.0024 17.6 0.0 0.0076 16.0 0.0 1.7 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.16 AAZ34129.1 - 0.0027 17.5 0.0 0.0045 16.8 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_11 PF08241.12 AAZ34129.1 - 0.0028 18.2 0.0 0.011 16.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAZ34129.1 - 0.013 15.4 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.10 AAZ34129.1 - 0.013 15.0 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PDGF PF00341.17 AAZ34129.1 - 0.17 12.2 0.1 0.36 11.2 0.1 1.5 1 0 0 1 1 1 0 PDGF/VEGF domain S4 PF01479.25 AAZ34130.1 - 1.7e-10 40.4 0.0 3.3e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 S4 domain PTS-HPr PF00381.19 AAZ34131.1 - 7.3e-27 93.4 0.1 8e-27 93.3 0.1 1.0 1 0 0 1 1 1 1 PTS HPr component phosphorylation site UPF0020 PF01170.18 AAZ34132.1 - 2e-47 161.4 0.0 6.3e-43 146.8 0.0 2.3 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 Methyltrans_SAM PF10672.9 AAZ34132.1 - 1e-19 70.8 0.0 1.5e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase Cons_hypoth95 PF03602.15 AAZ34132.1 - 5.5e-10 39.2 0.0 2.7e-07 30.4 0.0 2.4 2 0 0 2 2 2 2 Conserved hypothetical protein 95 THUMP PF02926.17 AAZ34132.1 - 3.7e-08 33.6 0.0 8.9e-08 32.3 0.0 1.6 2 0 0 2 2 2 1 THUMP domain Methyltransf_25 PF13649.6 AAZ34132.1 - 9.3e-05 23.1 0.0 0.0018 18.9 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.10 AAZ34132.1 - 0.0013 18.4 0.0 0.013 15.1 0.0 2.2 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_24 PF13578.6 AAZ34132.1 - 0.0084 17.1 0.0 0.068 14.2 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain GGDEF PF00990.21 AAZ34133.1 - 8.4e-47 158.9 0.0 1.2e-46 158.4 0.0 1.2 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain dCache_1 PF02743.18 AAZ34133.1 - 1.2e-12 48.1 0.1 2.5e-12 47.1 0.0 1.5 2 0 0 2 2 2 1 Cache domain GGDEF_2 PF17853.1 AAZ34133.1 - 0.005 17.1 0.3 0.015 15.6 0.1 1.9 2 0 0 2 2 2 1 GGDEF-like domain Phage_holin_5_2 PF16079.5 AAZ34133.1 - 0.13 12.6 0.4 0.85 10.0 0.1 2.3 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V DUF1970 PF09301.10 AAZ34133.1 - 0.2 11.9 1.3 1.4 9.2 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1970) HTH_18 PF12833.7 AAZ34134.1 - 1.3e-21 76.7 0.1 2.5e-21 75.7 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain DJ-1_PfpI PF01965.24 AAZ34134.1 - 8.5e-17 61.4 0.0 1.1e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family HTH_AraC PF00165.23 AAZ34134.1 - 2e-13 50.0 0.0 7.7e-07 29.1 0.0 2.7 3 0 0 3 3 3 2 Bacterial regulatory helix-turn-helix proteins, AraC family GGDEF PF00990.21 AAZ34135.1 - 3.5e-48 163.4 0.0 5e-48 162.9 0.0 1.2 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Response_reg PF00072.24 AAZ34135.1 - 3.3e-18 65.9 0.0 7.4e-18 64.8 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain TonB_2 PF13103.6 AAZ34136.1 - 9.6e-11 41.8 0.0 2.4e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 TonB C terminal TonB_C PF03544.14 AAZ34136.1 - 4.6e-07 30.2 1.3 1.9e-05 25.0 0.0 3.0 2 0 0 2 2 2 1 Gram-negative bacterial TonB protein C-terminal Mitofilin PF09731.9 AAZ34136.1 - 1.1 8.0 63.2 1.6 7.5 63.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Hamartin PF04388.12 AAZ34136.1 - 10 4.7 28.5 13 4.3 28.5 1.1 1 0 0 1 1 1 0 Hamartin protein DFP PF04127.15 AAZ34137.1 - 1.6e-70 236.8 0.1 1.6e-69 233.5 0.0 2.1 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein Flavoprotein PF02441.19 AAZ34137.1 - 1.1e-41 142.2 0.0 2e-41 141.4 0.0 1.3 1 0 0 1 1 1 1 Flavoprotein Glyco_trans_4_4 PF13579.6 AAZ34137.1 - 0.0015 18.9 6.1 0.63 10.5 0.1 2.8 2 1 0 2 2 2 2 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 AAZ34137.1 - 0.093 12.7 1.1 25 4.8 0.1 3.2 2 2 0 3 3 3 0 Glycosyltransferase Family 4 PspC PF04024.12 AAZ34137.1 - 0.19 11.6 0.2 0.4 10.5 0.2 1.5 1 0 0 1 1 1 0 PspC domain rpo30_N PF12410.8 AAZ34138.1 - 0.086 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Poxvirus DNA dependent RNA polymerase 30kDa subunit Cys_Met_Meta_PP PF01053.20 AAZ34139.1 - 4.9e-92 308.4 0.0 1.2e-91 307.1 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 AAZ34139.1 - 0.049 12.9 0.0 0.069 12.4 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 AAZ34139.1 - 0.079 11.9 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V PEP-utilizers_C PF02896.18 AAZ34140.1 - 1.6e-104 349.2 0.0 2.5e-104 348.5 0.0 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PTS_EIIA_2 PF00359.22 AAZ34140.1 - 2.4e-34 118.3 0.0 5.7e-28 97.6 0.0 2.6 2 0 0 2 2 2 2 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 PEP-utilisers_N PF05524.13 AAZ34140.1 - 1.5e-24 86.4 3.7 1.5e-24 86.4 3.7 2.3 2 0 0 2 2 2 1 PEP-utilising enzyme, N-terminal PEP-utilizers PF00391.23 AAZ34140.1 - 3.6e-21 74.7 0.2 9.2e-21 73.4 0.2 1.7 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain PTS-HPr PF00381.19 AAZ34140.1 - 1.9e-18 66.5 0.2 5.1e-18 65.1 0.2 1.8 1 0 0 1 1 1 1 PTS HPr component phosphorylation site HpcH_HpaI PF03328.14 AAZ34140.1 - 0.00059 19.0 0.0 0.0021 17.2 0.0 1.9 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Val_tRNA-synt_C PF10458.9 AAZ34140.1 - 0.18 12.1 1.4 2.3 8.5 0.1 2.6 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm GGDEF PF00990.21 AAZ34141.1 - 1.4e-40 138.7 0.4 1.8e-40 138.3 0.4 1.2 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain GGDEF_2 PF17853.1 AAZ34141.1 - 0.0052 17.0 0.3 0.01 16.1 0.3 1.6 1 1 0 1 1 1 1 GGDEF-like domain MLANA PF14991.6 AAZ34141.1 - 0.55 10.5 3.3 9.8 6.5 1.5 2.4 2 0 0 2 2 2 0 Protein melan-A TMCCDC2 PF15844.5 AAZ34141.1 - 0.71 9.8 4.4 0.44 10.5 0.7 2.1 2 0 0 2 2 2 0 Transmembrane and coiled-coil domain-containing protein 2 ThrE PF06738.12 AAZ34141.1 - 9.2 5.6 13.8 0.1 11.9 3.9 2.4 2 1 1 3 3 3 0 Putative threonine/serine exporter Condensation PF00668.20 AAZ34142.1 - 9.1e-09 34.5 0.0 0.0027 16.5 0.0 3.1 2 1 0 2 2 2 2 Condensation domain Glycos_transf_4 PF00953.21 AAZ34143.1 - 2.5e-36 125.1 12.7 2.5e-36 125.1 12.7 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 4 MraY_sig1 PF10555.9 AAZ34143.1 - 2.9e-05 23.4 0.7 2.9e-05 23.4 0.7 2.6 2 0 0 2 2 2 1 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 DUF4567 PF15131.6 AAZ34143.1 - 0.083 13.0 0.4 0.77 9.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4567) Tim29 PF10171.9 AAZ34143.1 - 0.11 12.0 0.0 0.64 9.5 0.0 1.9 2 0 0 2 2 2 0 Translocase of the Inner Mitochondrial membrane 29 Glycos_transf_2 PF00535.26 AAZ34144.1 - 1.2e-44 152.1 0.1 5.5e-22 78.4 0.0 2.8 3 0 0 3 3 3 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAZ34144.1 - 1.8e-28 100.0 0.4 1.4e-17 64.4 0.1 3.7 4 0 0 4 4 4 2 Glycosyltransferase like family 2 Glyco_tranf_2_5 PF13712.6 AAZ34144.1 - 1.2e-09 38.2 0.0 2.2e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family Glyco_tranf_2_2 PF10111.9 AAZ34144.1 - 5.5e-07 29.3 0.1 0.0098 15.4 0.0 4.2 3 1 0 3 3 3 1 Glycosyltransferase like family 2 Glyco_trans_1_4 PF13692.6 AAZ34144.1 - 7.2e-06 26.5 0.0 1.8e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_2_3 PF13632.6 AAZ34144.1 - 0.0031 17.4 0.6 0.12 12.3 0.1 2.6 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 AAZ34144.1 - 0.007 15.9 0.4 0.15 11.5 0.0 2.9 3 0 0 3 3 3 1 Glycosyl transferase family 21 RNase_E_G PF10150.9 AAZ34144.1 - 0.051 13.0 0.0 2.1 7.7 0.0 2.2 2 0 0 2 2 2 0 Ribonuclease E/G family YGGT PF02325.17 AAZ34145.1 - 6.6e-40 135.4 16.4 1.5e-20 73.3 2.6 2.2 2 0 0 2 2 2 2 YGGT family adh_short PF00106.25 AAZ34146.1 - 8e-43 146.2 0.6 9.8e-43 145.9 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAZ34146.1 - 6.6e-31 107.7 0.8 8.5e-31 107.3 0.8 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 AAZ34146.1 - 8.7e-08 31.9 0.0 2.2e-07 30.6 0.0 1.6 2 1 0 2 2 2 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 AAZ34146.1 - 1.5e-05 24.6 0.3 2.5e-05 23.8 0.3 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 AAZ34146.1 - 2.8e-05 24.1 1.0 4.4e-05 23.5 1.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 AAZ34146.1 - 0.00093 19.1 0.4 0.0017 18.3 0.4 1.6 2 0 0 2 2 2 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 AAZ34146.1 - 0.0049 16.0 0.3 0.01 15.0 0.1 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain NmrA PF05368.13 AAZ34146.1 - 0.052 13.1 0.2 0.083 12.4 0.2 1.3 1 0 0 1 1 1 0 NmrA-like family IstB_IS21 PF01695.17 AAZ34147.1 - 5.6e-62 208.6 0.1 8.3e-62 208.1 0.1 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein Bac_DnaA PF00308.18 AAZ34147.1 - 2.4e-06 27.5 0.0 3.4e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial dnaA protein AAA_28 PF13521.6 AAZ34147.1 - 4.2e-05 23.9 0.0 0.0002 21.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 AAZ34147.1 - 0.0013 18.2 0.1 0.0053 16.2 0.0 1.9 2 0 0 2 2 2 1 PhoH-like protein AAA PF00004.29 AAZ34147.1 - 0.0025 18.2 0.0 0.0047 17.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 AAZ34147.1 - 0.0041 16.9 0.0 0.0064 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 AAZ34147.1 - 0.017 15.5 0.1 0.046 14.1 0.1 1.8 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 AAZ34147.1 - 0.023 14.1 0.0 0.041 13.2 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.6 AAZ34147.1 - 0.025 15.0 0.1 0.05 14.0 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain A_deamin PF02137.18 AAZ34147.1 - 0.039 13.4 0.0 0.067 12.6 0.0 1.3 1 0 0 1 1 1 0 Adenosine-deaminase (editase) domain Parvo_NS1 PF01057.17 AAZ34147.1 - 0.043 12.9 0.2 1.4 7.9 0.0 2.3 1 1 1 2 2 2 0 Parvovirus non-structural protein NS1 FtsK_SpoIIIE PF01580.18 AAZ34147.1 - 0.044 13.1 0.0 0.078 12.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Mg_chelatase PF01078.21 AAZ34147.1 - 0.052 12.9 0.0 0.13 11.6 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 AAZ34147.1 - 0.06 13.6 0.4 0.37 11.1 0.1 2.3 2 1 1 3 3 3 0 AAA domain AAA_33 PF13671.6 AAZ34147.1 - 0.073 13.2 1.6 0.27 11.4 1.6 2.1 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AAZ34147.1 - 0.076 12.7 0.0 0.2 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 AAZ34147.1 - 0.096 12.2 0.0 0.44 10.0 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region OpuAC PF04069.12 AAZ34148.1 - 1.1e-60 205.5 9.7 1.2e-60 205.3 9.7 1.0 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system SBP_bac_3 PF00497.20 AAZ34148.1 - 0.0044 16.5 0.2 0.0056 16.1 0.2 1.4 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 OMPdecase PF00215.24 AAZ34149.1 - 1.3e-48 165.5 0.0 1.5e-48 165.3 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family PCuAC PF04314.13 AAZ34150.1 - 0.043 13.6 0.1 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 Copper chaperone PCu(A)C YcgR_2 PF12945.7 AAZ34150.1 - 0.07 13.3 0.1 0.16 12.1 0.0 1.7 1 1 1 2 2 2 0 Flagellar protein YcgR BPD_transp_1 PF00528.22 AAZ34151.1 - 3.6e-32 111.6 10.4 3.6e-32 111.6 10.4 2.3 2 1 0 2 2 2 2 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 AAZ34151.1 - 1.5e-11 44.1 1.1 1.5e-11 44.1 1.1 3.4 4 0 0 4 4 4 1 N-terminal TM domain of oligopeptide transport permease C Response_reg PF00072.24 AAZ34152.1 - 2.5e-25 88.8 0.0 3.8e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAZ34152.1 - 6.3e-16 58.2 0.0 1.2e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Mur_ligase_M PF08245.12 AAZ34153.1 - 1e-25 90.9 0.0 1.5e-25 90.3 0.0 1.3 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 AAZ34153.1 - 2.1e-08 34.3 0.0 1.8e-07 31.3 0.0 2.4 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain PAAR_motif PF05488.13 AAZ34154.1 - 8.5e-30 102.7 16.0 1.5e-17 63.5 1.3 3.6 2 1 2 4 4 4 3 PAAR motif GH-E PF14410.6 AAZ34154.1 - 1.8e-23 82.7 0.4 3.1e-23 81.9 0.4 1.4 1 0 0 1 1 1 1 HNH/ENDO VII superfamily nuclease with conserved GHE residues DUF4150 PF13665.6 AAZ34154.1 - 0.0019 18.3 0.3 2.1 8.6 0.2 3.0 2 1 1 3 3 3 2 Domain of unknown function (DUF4150) TraT PF05818.12 AAZ34154.1 - 0.041 13.6 7.4 0.08 12.6 0.1 2.3 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein Fe-S_biosyn PF01521.20 AAZ34155.1 - 3.3e-23 82.0 0.0 3.7e-23 81.8 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis PAAR_motif PF05488.13 AAZ34156.1 - 3.7e-16 59.1 9.2 2.1e-11 43.8 4.1 2.6 1 1 2 3 3 3 3 PAAR motif PBSX_XtrA PF17356.2 AAZ34156.1 - 0.043 13.7 0.1 0.21 11.5 0.0 2.0 2 0 0 2 2 2 0 Phage-like element PBSX protein XtrA Spore_IV_A PF09547.10 AAZ34156.1 - 0.28 10.1 0.0 0.36 9.7 0.0 1.0 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) T2SSC PF11356.8 AAZ34157.1 - 3.2e-06 27.1 3.1 3.4e-06 27.0 0.4 1.9 1 1 1 2 2 2 1 Type II secretion system protein C TLP1_add_C PF18313.1 AAZ34157.1 - 0.092 12.7 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Thiolase-like protein type 1 additional C-terminal domain T2SSB PF16537.5 AAZ34157.1 - 0.17 11.5 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Type II secretion system protein B FolB PF02152.18 AAZ34158.1 - 4.1e-31 107.8 0.0 4.5e-31 107.7 0.0 1.0 1 0 0 1 1 1 1 Dihydroneopterin aldolase Acyltransferase PF01553.21 AAZ34159.1 - 2.2e-08 33.8 0.0 6.1e-08 32.4 0.0 1.7 1 1 0 1 1 1 1 Acyltransferase ACPS PF01648.20 AAZ34161.1 - 2.2e-05 24.5 0.0 3.4e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily MdcE PF06833.11 AAZ34162.1 - 1.8e-98 328.6 7.6 2.1e-98 328.5 7.6 1.0 1 0 0 1 1 1 1 Malonate decarboxylase gamma subunit (MdcE) HAD PF12710.7 AAZ34163.1 - 5.8e-43 147.5 0.2 7.1e-43 147.2 0.2 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AAZ34163.1 - 0.0008 19.2 0.9 0.068 12.9 0.0 2.9 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAZ34163.1 - 0.0039 17.5 0.0 0.056 13.7 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 AAZ34163.1 - 0.021 14.9 0.0 0.033 14.3 0.0 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Asp1 PF16993.5 AAZ34163.1 - 0.024 13.9 0.0 0.032 13.5 0.0 1.1 1 0 0 1 1 1 0 Accessory Sec system protein Asp1 Put_Phosphatase PF06888.12 AAZ34163.1 - 0.094 12.1 0.0 0.22 10.9 0.0 1.6 1 1 0 1 1 1 0 Putative Phosphatase Metallophos_2 PF12850.7 AAZ34164.1 - 2.4e-33 115.7 0.1 2.7e-33 115.5 0.1 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 AAZ34164.1 - 4.7e-06 27.2 0.6 0.0018 18.8 0.1 2.2 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase Transgly PF00912.22 AAZ34165.1 - 4.3e-50 169.6 0.0 6e-50 169.2 0.0 1.2 1 0 0 1 1 1 1 Transglycosylase BiPBP_C PF06832.12 AAZ34165.1 - 6.7e-19 67.7 0.6 3.8e-18 65.3 0.0 2.5 3 0 0 3 3 3 1 Penicillin-Binding Protein C-terminus Family Transpeptidase PF00905.22 AAZ34165.1 - 8e-11 41.7 0.0 2.1e-08 33.7 0.0 2.1 2 0 0 2 2 2 2 Penicillin binding protein transpeptidase domain Ribonuc_L-PSP PF01042.21 AAZ34166.1 - 7.9e-17 61.4 0.0 1.1e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP FhuF PF06276.12 AAZ34167.1 - 0.05 14.0 1.3 0.12 12.8 1.1 1.7 1 1 0 1 1 1 0 Ferric iron reductase FhuF-like transporter AMP-binding PF00501.28 AAZ34168.1 - 5.6e-53 180.0 0.0 7e-53 179.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AvrE_T3Es PF11725.8 AAZ34169.1 - 0 2900.8 32.1 0 2843.7 13.4 2.0 1 1 1 2 2 2 2 AvrE-family Type-III effector proteins (T3Es) Lectin_N PF03954.14 AAZ34169.1 - 0.049 13.4 0.1 0.19 11.5 0.1 2.0 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain MCPsignal PF00015.21 AAZ34170.1 - 7.1e-49 165.9 23.2 7.1e-49 165.9 23.2 3.5 3 1 1 4 4 4 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AAZ34170.1 - 2.2e-08 34.3 5.0 5.2e-08 33.1 0.4 3.6 4 0 0 4 4 4 1 HAMP domain 4HB_MCP_1 PF12729.7 AAZ34170.1 - 1.2e-07 31.5 2.9 1.2e-07 31.5 2.9 3.0 3 1 0 3 3 3 1 Four helix bundle sensory module for signal transduction DHR10 PF18595.1 AAZ34170.1 - 0.024 14.7 11.3 1.2 9.2 0.0 4.4 4 1 0 4 4 4 0 Designed helical repeat protein 10 domain BMFP PF04380.13 AAZ34170.1 - 0.59 10.7 3.9 57 4.3 0.1 4.3 3 1 1 4 4 4 0 Membrane fusogenic activity DUF1664 PF07889.12 AAZ34170.1 - 0.6 10.2 13.0 6.5 6.8 2.8 4.3 3 3 2 5 5 5 0 Protein of unknown function (DUF1664) FliT PF05400.13 AAZ34170.1 - 0.64 10.9 9.6 1.8 9.4 0.1 4.4 2 2 3 5 5 5 0 Flagellar protein FliT ApoLp-III PF07464.11 AAZ34170.1 - 8.1 6.5 12.3 2.7 8.1 5.1 3.4 2 2 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Vps53_N PF04100.12 AAZ34170.1 - 9.1 5.1 11.8 1 8.3 3.6 2.6 3 0 0 3 3 3 0 Vps53-like, N-terminal Fib_alpha PF08702.10 AAZ34170.1 - 9.5 6.4 9.2 18 5.5 1.4 3.8 3 3 0 3 3 3 0 Fibrinogen alpha/beta chain family GTP_EFTU PF00009.27 AAZ34171.1 - 2.2e-51 174.2 0.1 3.5e-51 173.5 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 AAZ34171.1 - 4.4e-50 168.3 2.9 7.7e-50 167.5 2.9 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 AAZ34171.1 - 4.7e-20 71.4 0.0 3.9e-19 68.5 0.0 2.5 3 0 0 3 3 3 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 AAZ34171.1 - 1e-08 35.4 3.3 8.5e-08 32.5 1.9 2.6 3 0 0 3 3 3 1 Elongation factor Tu domain 2 EFG_II PF14492.6 AAZ34171.1 - 4.1e-05 23.6 0.0 0.00035 20.6 0.0 2.5 1 1 0 1 1 1 1 Elongation Factor G, domain II Ras PF00071.22 AAZ34171.1 - 5.9e-05 22.7 0.0 0.00012 21.7 0.0 1.5 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.23 AAZ34171.1 - 0.00033 20.7 0.0 0.0028 17.7 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase RF3_C PF16658.5 AAZ34171.1 - 0.0049 16.7 0.0 0.0091 15.8 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Arf PF00025.21 AAZ34171.1 - 0.1 12.1 0.1 0.45 10.0 0.0 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family FMO-like PF00743.19 AAZ34172.1 - 5.8e-51 173.5 0.0 7.4e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 AAZ34172.1 - 5.4e-25 88.3 0.0 1e-22 80.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 AAZ34172.1 - 1.4e-12 47.5 0.0 1.5e-09 37.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 AAZ34172.1 - 1.3e-11 44.2 0.0 1e-10 41.3 0.0 2.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 AAZ34172.1 - 1.4e-06 28.4 0.3 7.2e-06 26.2 0.1 2.4 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 AAZ34172.1 - 2.8e-06 27.4 1.8 0.00033 20.7 0.3 3.7 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 AAZ34172.1 - 5.3e-06 26.2 0.1 0.001 18.7 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 AAZ34172.1 - 2e-05 24.1 0.0 0.01 15.2 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 AAZ34172.1 - 0.0011 19.4 0.1 3.5 8.3 0.0 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AAZ34172.1 - 0.012 14.3 0.1 0.88 8.2 0.0 2.4 3 0 0 3 3 3 0 HI0933-like protein FAD_binding_3 PF01494.19 AAZ34172.1 - 0.021 14.1 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 AAZ34172.1 - 0.069 12.2 0.1 5 6.1 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein TENA_THI-4 PF03070.16 AAZ34173.1 - 4.7e-64 216.0 0.0 5.5e-64 215.8 0.0 1.0 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Haem_oxygenas_2 PF14518.6 AAZ34173.1 - 0.0016 18.2 0.1 0.0023 17.7 0.1 1.3 1 0 0 1 1 1 1 Iron-containing redox enzyme BON PF04972.17 AAZ34174.1 - 1.2e-13 51.2 3.1 2e-13 50.4 3.1 1.4 1 0 0 1 1 1 1 BON domain DUF469 PF04320.14 AAZ34174.1 - 0.0082 17.0 0.2 0.011 16.6 0.2 1.2 1 0 0 1 1 1 1 Protein with unknown function (DUF469) TraI_2 PF07514.11 AAZ34174.1 - 0.014 14.4 0.2 0.016 14.2 0.2 1.1 1 0 0 1 1 1 0 Putative helicase DUF4832 PF16116.5 AAZ34174.1 - 0.069 13.0 0.3 0.083 12.7 0.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4832) DUF4179 PF13786.6 AAZ34174.1 - 0.51 10.8 6.3 0.78 10.3 6.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4179) Lon_C PF05362.13 AAZ34175.1 - 6e-97 323.1 1.9 1e-96 322.4 1.9 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 AAZ34175.1 - 2e-42 145.5 0.2 4.2e-42 144.4 0.2 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 AAZ34175.1 - 6.9e-22 78.3 0.0 7.1e-20 71.8 0.0 3.1 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AAZ34175.1 - 1.1e-10 41.7 0.0 7.5e-10 38.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 AAZ34175.1 - 6.4e-07 29.2 0.0 2.2e-06 27.5 0.0 2.0 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_PrkA PF08298.11 AAZ34175.1 - 2.2e-06 26.8 0.0 4.5e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_16 PF13191.6 AAZ34175.1 - 2.2e-05 24.9 1.9 0.00013 22.4 0.0 2.9 3 1 0 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.17 AAZ34175.1 - 0.00014 21.6 0.0 0.00031 20.5 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.14 AAZ34175.1 - 0.00065 19.9 0.0 0.01 16.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 AAZ34175.1 - 0.00085 19.1 0.6 0.0022 17.8 0.0 2.0 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 AAZ34175.1 - 0.0013 19.0 0.1 0.021 15.1 0.0 2.9 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 AAZ34175.1 - 0.0045 16.9 0.0 0.096 12.6 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_23 PF13476.6 AAZ34175.1 - 0.0083 16.6 1.7 4.1 7.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 AAZ34175.1 - 0.01 15.7 0.0 0.041 13.8 0.0 2.1 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 AAZ34175.1 - 0.011 16.3 0.2 0.043 14.3 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 AAZ34175.1 - 0.011 15.7 0.0 0.036 14.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 AAZ34175.1 - 0.012 15.7 0.1 0.43 10.7 0.0 2.8 3 0 0 3 3 2 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 AAZ34175.1 - 0.02 14.8 0.0 0.053 13.4 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase NB-ARC PF00931.22 AAZ34175.1 - 0.024 13.8 0.0 0.049 12.8 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.6 AAZ34175.1 - 0.025 14.7 0.2 0.072 13.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.6 AAZ34175.1 - 0.026 14.2 0.0 0.15 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 AAZ34175.1 - 0.029 14.3 0.3 0.42 10.5 0.0 2.6 2 0 0 2 2 2 0 NTPase RNA_helicase PF00910.22 AAZ34175.1 - 0.046 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ATP-synt_ab PF00006.25 AAZ34175.1 - 0.061 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_28 PF13521.6 AAZ34175.1 - 0.12 12.7 0.0 0.43 10.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AAZ34175.1 - 0.12 12.0 0.6 1.4 8.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 AAZ34175.1 - 0.12 12.9 2.0 0.5 10.9 0.0 2.9 3 1 0 3 3 3 0 ABC transporter Roc PF08477.13 AAZ34175.1 - 0.14 12.4 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 AAZ34175.1 - 0.16 11.9 0.0 0.42 10.6 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 AAZ34175.1 - 0.2 12.0 0.9 0.75 10.1 0.1 2.4 3 0 0 3 3 2 0 AAA domain DUF1365 PF07103.11 AAZ34176.1 - 4.7e-68 229.4 0.0 5.4e-68 229.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) Acetyltransf_18 PF18014.1 AAZ34177.1 - 4.3e-21 75.0 0.0 8e-20 70.9 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAZ34177.1 - 2.3e-14 53.4 0.0 3.6e-13 49.6 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAZ34177.1 - 1.2e-11 44.9 0.0 3e-11 43.6 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAZ34177.1 - 4.9e-10 39.7 0.0 1.6e-08 34.8 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.10 AAZ34177.1 - 0.0075 16.2 0.1 0.022 14.7 0.0 1.8 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.6 AAZ34177.1 - 0.012 15.7 0.0 0.029 14.5 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 AAZ34177.1 - 0.013 15.6 0.0 0.23 11.6 0.0 2.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain RepB PF07506.11 AAZ34178.1 - 3.5e-49 167.4 0.1 4.5e-49 167.1 0.1 1.1 1 0 0 1 1 1 1 RepB plasmid partitioning protein ParBc PF02195.18 AAZ34178.1 - 1.9e-07 31.2 0.0 1.4e-06 28.5 0.0 2.1 2 0 0 2 2 2 1 ParB-like nuclease domain HTH_11 PF08279.12 AAZ34178.1 - 0.0019 18.1 0.0 0.006 16.5 0.0 1.9 1 0 0 1 1 1 1 HTH domain Sigma70_r4 PF04545.16 AAZ34178.1 - 0.0087 15.6 0.2 0.067 12.7 0.1 2.3 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_50 PF18024.1 AAZ34178.1 - 0.0098 15.5 0.1 0.024 14.2 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_20 PF12840.7 AAZ34178.1 - 0.019 15.0 0.0 0.14 12.3 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_AsnC-type PF13404.6 AAZ34178.1 - 0.023 14.5 0.0 0.092 12.6 0.0 2.0 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_3 PF01381.22 AAZ34178.1 - 0.029 14.4 0.3 0.23 11.6 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix ParBc_2 PF08857.11 AAZ34178.1 - 0.073 13.2 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative ParB-like nuclease HTH_28 PF13518.6 AAZ34178.1 - 0.1 12.8 0.6 0.29 11.3 0.0 2.1 2 0 0 2 2 1 0 Helix-turn-helix domain Glyco_trans_4_2 PF13477.6 AAZ34178.1 - 0.12 12.4 0.1 0.36 10.9 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase 4-like HTH_23 PF13384.6 AAZ34178.1 - 0.13 12.0 0.1 0.49 10.3 0.1 2.0 1 0 0 1 1 1 0 Homeodomain-like domain MCPsignal PF00015.21 AAZ34180.1 - 1.1e-44 152.3 34.5 4.9e-42 143.7 24.3 2.5 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AAZ34180.1 - 3.7e-16 59.3 11.2 1e-10 41.8 0.1 5.1 4 1 0 4 4 4 3 HAMP domain DUF948 PF06103.11 AAZ34180.1 - 0.03 14.6 0.9 0.03 14.6 0.9 5.7 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Glyoxalase PF00903.25 AAZ34180.1 - 0.047 13.9 0.2 0.15 12.3 0.1 1.9 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily APG17 PF04108.12 AAZ34180.1 - 0.11 11.6 15.7 0.017 14.2 5.2 2.3 1 1 1 2 2 2 0 Autophagy protein Apg17 DUF724 PF05266.14 AAZ34180.1 - 0.33 10.7 6.5 1.1 9.1 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF724) Seryl_tRNA_N PF02403.22 AAZ34180.1 - 0.47 10.7 7.7 1.6 9.0 2.2 3.3 1 1 3 4 4 4 0 Seryl-tRNA synthetase N-terminal domain DUF2064 PF09837.9 AAZ34180.1 - 0.5 10.2 11.1 2.2 8.1 1.2 4.2 2 2 2 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2064) DUF1664 PF07889.12 AAZ34180.1 - 0.54 10.3 17.8 4.3 7.4 3.1 4.1 2 2 3 5 5 5 0 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.11 AAZ34180.1 - 0.8 10.3 7.1 7.2 7.2 0.1 3.7 2 2 2 4 4 4 0 Syntaxin 6, N-terminal CTU2 PF10288.9 AAZ34180.1 - 1.3 9.3 3.9 5.2 7.3 3.6 2.3 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 FlgN PF05130.12 AAZ34180.1 - 3.1 8.3 17.3 3 8.3 2.2 3.8 2 1 1 4 4 4 0 FlgN protein Laminin_II PF06009.12 AAZ34180.1 - 6.1 6.9 20.5 2.7 8.0 0.3 4.0 1 1 3 4 4 4 0 Laminin Domain II AIP3 PF03915.13 AAZ34180.1 - 7.4 5.6 14.9 1.2 8.1 4.4 2.3 1 1 1 2 2 2 0 Actin interacting protein 3 ABC_tran PF00005.27 AAZ34181.1 - 2.5e-56 190.0 0.0 6.5e-32 110.9 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 AAZ34181.1 - 3.3e-10 40.3 0.2 0.0027 17.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AAZ34181.1 - 0.0004 20.1 0.1 0.0047 16.6 0.0 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AAZ34181.1 - 0.00052 20.3 1.8 0.32 11.3 0.3 3.8 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.6 AAZ34181.1 - 0.002 18.5 0.0 0.076 13.4 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 AAZ34181.1 - 0.0038 16.7 2.8 0.85 9.0 0.7 3.5 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 AAZ34181.1 - 0.013 15.3 0.2 0.12 12.1 0.1 2.6 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 AAZ34181.1 - 0.014 15.3 0.0 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase CP_ATPgrasp_2 PF14403.6 AAZ34181.1 - 0.017 14.0 0.0 0.031 13.2 0.0 1.3 1 0 0 1 1 1 0 Circularly permuted ATP-grasp type 2 AAA_23 PF13476.6 AAZ34181.1 - 0.023 15.2 0.1 0.14 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain MukB PF04310.12 AAZ34181.1 - 0.051 13.4 0.0 0.17 11.7 0.0 1.8 2 0 0 2 2 2 0 MukB N-terminal AAA PF00004.29 AAZ34181.1 - 0.082 13.3 1.1 1.6 9.2 0.5 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 AAZ34181.1 - 0.098 12.7 0.1 0.67 10.0 0.0 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_ATPase PF09818.9 AAZ34181.1 - 0.11 11.3 2.0 22 3.7 0.1 3.2 3 0 0 3 3 3 0 Predicted ATPase of the ABC class Zeta_toxin PF06414.12 AAZ34181.1 - 0.21 10.8 0.1 2.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_15 PF13175.6 AAZ34181.1 - 0.26 10.9 0.0 0.32 10.7 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain ATPase PF06745.13 AAZ34182.1 - 5.9e-77 258.1 0.1 1.1e-41 142.7 0.0 2.0 2 0 0 2 2 2 2 KaiC AAA_25 PF13481.6 AAZ34182.1 - 8.6e-16 58.1 1.4 1.2e-06 28.2 0.1 3.0 2 2 0 2 2 2 2 AAA domain DnaB_C PF03796.15 AAZ34182.1 - 4.5e-11 42.6 1.2 0.0021 17.5 0.2 4.2 3 2 0 3 3 3 2 DnaB-like helicase C terminal domain Rad51 PF08423.11 AAZ34182.1 - 6.8e-11 41.9 0.1 3.9e-06 26.3 0.0 2.5 2 0 0 2 2 2 2 Rad51 AAA_16 PF13191.6 AAZ34182.1 - 3.5e-09 37.3 1.6 0.00053 20.4 0.3 2.4 2 0 0 2 2 2 2 AAA ATPase domain RecA PF00154.21 AAZ34182.1 - 1.8e-08 34.2 1.2 2.4e-05 24.0 0.1 2.3 2 0 0 2 2 2 2 recA bacterial DNA recombination protein PAXNEB PF05625.11 AAZ34182.1 - 2.9e-08 33.3 4.1 7e-05 22.1 0.2 3.3 3 0 0 3 3 3 2 PAXNEB protein IstB_IS21 PF01695.17 AAZ34182.1 - 3.4e-08 33.4 2.3 0.0012 18.6 0.1 3.5 3 1 0 3 3 3 2 IstB-like ATP binding protein AAA_24 PF13479.6 AAZ34182.1 - 1.8e-06 27.8 0.0 0.035 13.8 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 AAZ34182.1 - 2.8e-06 27.7 0.8 0.12 12.6 0.0 2.9 2 2 0 2 2 2 2 AAA domain AAA PF00004.29 AAZ34182.1 - 5.4e-06 26.9 0.0 0.026 14.9 0.0 2.8 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 AAZ34182.1 - 7e-06 25.6 0.3 0.0021 17.5 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein GvpD PF07088.11 AAZ34182.1 - 1.5e-05 23.8 0.5 7.4e-05 21.6 0.1 2.3 2 1 0 2 2 2 1 GvpD gas vesicle protein DUF2075 PF09848.9 AAZ34182.1 - 1.6e-05 24.3 0.1 0.01 15.1 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) MEDS PF14417.6 AAZ34182.1 - 4e-05 23.5 0.1 0.39 10.5 0.0 2.6 2 0 0 2 2 2 2 MEDS: MEthanogen/methylotroph, DcmR Sensory domain AAA_11 PF13086.6 AAZ34182.1 - 4.3e-05 23.4 0.0 0.0078 16.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 AAZ34182.1 - 4.3e-05 23.3 0.0 0.12 12.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 AAZ34182.1 - 4.4e-05 23.5 0.8 0.026 14.5 0.0 2.8 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 AAZ34182.1 - 7.3e-05 22.4 0.3 0.13 11.8 0.0 2.6 3 0 0 3 3 2 2 P-loop containing dynein motor region ABC_tran PF00005.27 AAZ34182.1 - 0.00038 21.0 0.1 0.43 11.1 0.0 2.6 2 1 0 2 2 2 1 ABC transporter Sigma54_activat PF00158.26 AAZ34182.1 - 0.0021 17.8 0.2 2.5 7.8 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain CbiA PF01656.23 AAZ34182.1 - 0.0023 18.0 0.2 1.7 8.7 0.0 2.6 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_19 PF13245.6 AAZ34182.1 - 0.0026 18.1 0.9 0.39 11.0 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 AAZ34182.1 - 0.0046 16.7 2.5 0.57 10.0 0.3 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 AAZ34182.1 - 0.0056 17.2 0.0 1.9 9.1 0.0 2.7 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 AAZ34182.1 - 0.0064 15.9 0.4 0.76 9.1 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_10 PF12846.7 AAZ34182.1 - 0.0099 14.8 0.0 0.099 11.5 0.0 2.0 2 0 0 2 2 2 1 AAA-like domain TniB PF05621.11 AAZ34182.1 - 0.015 14.7 0.2 11 5.4 0.0 3.5 4 0 0 4 4 4 0 Bacterial TniB protein AAA_33 PF13671.6 AAZ34182.1 - 0.016 15.4 0.0 0.24 11.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 AAZ34182.1 - 0.019 13.9 0.3 3.7 6.3 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ResIII PF04851.15 AAZ34182.1 - 0.024 14.6 0.1 8.1 6.4 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit NACHT PF05729.12 AAZ34182.1 - 0.063 13.2 3.7 1.1 9.1 0.0 3.4 3 1 0 3 3 3 0 NACHT domain RNA_helicase PF00910.22 AAZ34182.1 - 0.083 13.3 0.0 13 6.3 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Sigma54_activ_2 PF14532.6 AAZ34182.1 - 0.084 13.0 0.1 12 6.0 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain DAP3 PF10236.9 AAZ34182.1 - 0.1 11.7 0.1 0.43 9.7 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Zot PF05707.12 AAZ34182.1 - 0.1 12.2 0.0 6.4 6.4 0.0 2.3 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_14 PF13173.6 AAZ34182.1 - 0.1 12.6 0.0 5.2 7.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 AAZ34182.1 - 0.11 11.6 0.5 3.9 6.5 0.1 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein ATP-synt_ab PF00006.25 AAZ34182.1 - 0.17 11.5 0.1 13 5.3 0.0 2.7 3 1 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DEAD PF00270.29 AAZ34182.1 - 0.29 10.9 1.4 13 5.5 0.3 3.0 2 1 0 2 2 2 0 DEAD/DEAH box helicase V-ATPase_G PF03179.15 AAZ34183.1 - 0.011 16.2 0.3 4.7 7.8 0.1 2.1 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit LysR_substrate PF03466.20 AAZ34184.1 - 9.8e-46 155.7 1.7 1.5e-45 155.2 1.7 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ34184.1 - 3.4e-14 52.5 0.8 7.6e-14 51.4 0.8 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_29 PF13551.6 AAZ34184.1 - 0.13 12.3 0.2 0.3 11.2 0.2 1.6 1 0 0 1 1 1 0 Winged helix-turn helix CheW PF01584.19 AAZ34185.1 - 9.7e-15 54.4 0.0 2e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 CheW-like domain Phage_integrase PF00589.22 AAZ34186.1 - 2.6e-06 27.3 0.4 5.2e-06 26.4 0.4 1.5 1 0 0 1 1 1 1 Phage integrase family Glyco_transf_56 PF07429.11 AAZ34187.1 - 0.018 14.2 0.3 0.023 13.8 0.3 1.1 1 0 0 1 1 1 0 4-alpha-L-fucosyltransferase glycosyl transferase group 56 DP PF08781.10 AAZ34187.1 - 0.024 14.6 0.2 0.036 13.9 0.2 1.3 1 0 0 1 1 1 0 Transcription factor DP Xpo1 PF08389.12 AAZ34187.1 - 0.05 13.6 0.1 0.072 13.1 0.1 1.4 1 1 0 1 1 1 0 Exportin 1-like protein ketoacyl-synt PF00109.26 AAZ34188.1 - 8.3e-46 156.6 0.3 7.5e-44 150.2 0.2 2.0 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 AAZ34188.1 - 1.5e-26 92.7 0.0 2.7e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 AAZ34188.1 - 0.0012 18.3 0.0 0.0091 15.4 0.0 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain PALP PF00291.25 AAZ34189.1 - 3.1e-45 154.8 0.1 4.1e-45 154.5 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF3034 PF11231.8 AAZ34190.1 - 5.3e-107 357.2 0.1 6.1e-107 357.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3034) Transposase_mut PF00872.18 AAZ34191.1 - 2e-117 392.3 0.0 2.5e-117 392.0 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ34191.1 - 7.8e-05 23.0 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain DUF3833 PF12915.7 AAZ34192.1 - 2.5e-65 219.0 0.0 2.9e-65 218.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3833) DsbD_2 PF13386.6 AAZ34193.1 - 7.5e-57 192.5 24.5 8.6e-57 192.3 24.5 1.0 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DsbD PF02683.15 AAZ34193.1 - 3.9e-10 40.0 5.4 3.9e-10 40.0 5.4 1.5 1 1 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region Thioesterase PF00975.20 AAZ34194.1 - 3.9e-10 40.2 0.2 1.1e-09 38.7 0.1 1.6 1 1 1 2 2 2 1 Thioesterase domain Hydrolase_4 PF12146.8 AAZ34194.1 - 5.1e-09 35.7 0.6 7.7e-08 31.9 0.2 2.0 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AAZ34194.1 - 9e-08 32.1 0.2 0.00019 21.2 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 AAZ34194.1 - 0.00063 19.4 0.0 0.00071 19.2 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 AAZ34194.1 - 0.002 17.6 0.1 0.025 14.1 0.1 2.0 1 1 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 AAZ34194.1 - 0.0043 16.9 0.0 0.0056 16.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAZ34194.1 - 0.0048 17.5 2.7 0.12 13.0 1.0 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family zf-RING_11 PF17123.5 AAZ34194.1 - 0.06 13.1 0.3 0.12 12.2 0.3 1.4 1 0 0 1 1 1 0 RING-like zinc finger DUF1989 PF09347.10 AAZ34195.1 - 2.2e-66 222.6 0.0 3.1e-66 222.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) PepSY_TM PF03929.16 AAZ34196.1 - 5.9e-58 196.8 6.3 7e-58 196.6 6.3 1.0 1 0 0 1 1 1 1 PepSY-associated TM region PepSY PF03413.19 AAZ34196.1 - 1.8e-08 34.8 0.0 0.016 15.8 0.0 2.9 2 1 0 2 2 2 2 Peptidase propeptide and YPEB domain adh_short_C2 PF13561.6 AAZ34197.1 - 1.5e-50 171.9 0.8 1.9e-50 171.6 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAZ34197.1 - 1.1e-44 152.2 0.7 1.4e-44 151.9 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAZ34197.1 - 8.8e-13 48.6 1.6 1.3e-12 47.9 1.6 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AAZ34197.1 - 0.0084 15.6 0.6 0.046 13.2 0.4 2.2 2 1 1 3 3 3 1 NAD dependent epimerase/dehydratase family Ribosom_S12_S23 PF00164.25 AAZ34198.1 - 7.2e-42 141.6 0.8 8.2e-42 141.4 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S12 PF17487.2 AAZ34198.1 - 0.14 12.9 0.0 0.29 11.9 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein S12 CPSase_L_D2 PF02786.17 AAZ34199.1 - 1.9e-73 246.4 0.1 2.8e-73 245.9 0.1 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 AAZ34199.1 - 2.3e-43 147.2 0.1 5.5e-43 146.0 0.1 1.7 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 AAZ34199.1 - 3.4e-40 136.5 0.0 7.8e-40 135.3 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 AAZ34199.1 - 5.8e-11 42.3 0.0 1.1e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 AAZ34199.1 - 2.6e-07 30.4 0.1 7.3e-07 28.9 0.1 1.7 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.11 AAZ34199.1 - 0.00038 20.1 0.0 0.0096 15.5 0.0 2.7 2 1 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 AAZ34199.1 - 0.005 16.9 0.0 0.013 15.5 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 AAZ34199.1 - 0.0057 16.3 0.0 0.013 15.1 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain SBP_bac_5 PF00496.22 AAZ34200.1 - 3e-68 230.5 0.0 3.6e-68 230.3 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle Acetyltransf_1 PF00583.25 AAZ34201.1 - 8.1e-09 35.7 0.0 1.1e-08 35.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AAZ34201.1 - 1.6e-08 34.5 0.0 2.2e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAZ34201.1 - 2.9e-07 30.8 0.0 4.6e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AAZ34201.1 - 4.4e-06 26.9 0.0 5.9e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AAZ34201.1 - 1.4e-05 25.8 0.0 1.9e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AAZ34201.1 - 0.047 13.8 0.0 0.1 12.7 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAZ34201.1 - 0.055 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein TPR_16 PF13432.6 AAZ34202.1 - 6.9 7.4 10.9 0.38 11.4 4.9 2.1 2 1 0 2 2 2 0 Tetratricopeptide repeat SpoU_methylase PF00588.19 AAZ34203.1 - 3.4e-16 59.7 0.0 4.8e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 SpoU rRNA Methylase family TPR_3 PF07720.12 AAZ34203.1 - 0.031 14.3 0.0 0.064 13.3 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF493 PF04359.14 AAZ34204.1 - 3.2e-22 78.9 0.0 4.1e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF493) ACT_4 PF13291.6 AAZ34204.1 - 0.0099 16.5 0.0 0.014 16.0 0.0 1.2 1 0 0 1 1 1 1 ACT domain GSH-S_ATP PF02955.16 AAZ34205.1 - 4.1e-78 260.8 0.0 5.5e-78 260.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain GSH-S_N PF02951.14 AAZ34205.1 - 7.2e-42 142.3 0.0 1e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, N-terminal domain RimK PF08443.11 AAZ34205.1 - 3.3e-11 43.2 0.0 4.5e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATPgrasp_YheCD PF14398.6 AAZ34205.1 - 0.00039 19.8 0.0 0.00062 19.1 0.0 1.3 1 0 0 1 1 1 1 YheC/D like ATP-grasp FKBP_C PF00254.28 AAZ34206.1 - 2.4e-12 47.0 0.0 3.5e-12 46.5 0.0 1.3 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Abhydrolase_1 PF00561.20 AAZ34208.1 - 4.2e-24 85.6 0.0 7.6e-24 84.7 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AAZ34208.1 - 1.4e-13 50.7 0.0 3.4e-13 49.4 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AAZ34208.1 - 7.1e-13 49.7 0.3 9e-13 49.3 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 AAZ34208.1 - 7e-06 25.8 0.0 1.1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Thioesterase PF00975.20 AAZ34208.1 - 0.097 12.8 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain NMT1 PF09084.11 AAZ34209.1 - 1.7e-20 73.9 0.0 2.3e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 AAZ34209.1 - 3.5e-17 62.9 0.3 9.2e-17 61.6 0.3 1.6 1 1 0 1 1 1 1 NMT1-like family OpuAC PF04069.12 AAZ34209.1 - 3.2e-13 49.9 0.6 4.6e-13 49.4 0.6 1.2 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system SBP_bac_3 PF00497.20 AAZ34209.1 - 2.6e-11 43.4 0.0 1e-10 41.5 0.0 1.8 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.7 AAZ34209.1 - 3.7e-08 33.3 0.3 7.4e-08 32.3 0.0 1.7 2 0 0 2 2 2 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1_3 PF16868.5 AAZ34209.1 - 8.9e-07 28.6 0.1 1.6e-06 27.8 0.0 1.5 2 0 0 2 2 2 1 NMT1-like family HEM4 PF02602.15 AAZ34209.1 - 0.091 12.1 0.2 0.38 10.1 0.0 2.1 2 1 0 2 2 2 0 Uroporphyrinogen-III synthase HemD GIDA PF01134.22 AAZ34210.1 - 2.7e-169 563.4 0.0 3.3e-169 563.1 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 AAZ34210.1 - 3.4e-76 256.1 0.0 4.7e-76 255.6 0.0 1.2 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 AAZ34210.1 - 6.2e-07 29.1 1.8 1e-06 28.4 1.8 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 AAZ34210.1 - 1.7e-06 27.5 0.3 5.1e-06 25.9 0.3 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AAZ34210.1 - 3.4e-06 26.4 5.5 0.0032 16.6 1.7 2.4 1 1 0 2 2 2 2 FAD binding domain AlaDh_PNT_C PF01262.21 AAZ34210.1 - 0.0014 18.0 0.1 0.0028 17.0 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 AAZ34210.1 - 0.0036 16.6 1.0 0.035 13.4 1.0 2.2 1 1 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 AAZ34210.1 - 0.052 14.1 0.3 0.12 13.0 0.3 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AAZ34210.1 - 0.053 12.2 4.3 0.044 12.5 0.7 2.4 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox_3 PF13738.6 AAZ34210.1 - 0.14 11.4 0.1 0.31 10.2 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AAZ34210.1 - 0.17 11.1 0.3 0.33 10.1 0.3 1.5 1 0 0 1 1 1 0 FAD binding domain AAA_23 PF13476.6 AAZ34211.1 - 5.7e-30 105.3 15.9 5.7e-30 105.3 15.9 8.4 1 1 2 4 4 4 1 AAA domain SbcCD_C PF13558.6 AAZ34211.1 - 1.8e-12 47.4 1.5 4.9e-12 45.9 0.4 2.5 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 AAZ34211.1 - 4.8e-07 29.4 9.0 2.3e-05 23.9 9.0 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAZ34211.1 - 1.5e-06 27.8 0.1 3.4e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 AAZ34211.1 - 8.4e-05 22.5 0.0 0.00024 21.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 AAZ34211.1 - 0.0025 17.9 0.4 0.019 15.0 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase KELK PF15796.5 AAZ34211.1 - 0.01 16.3 8.1 0.01 16.3 8.1 10.0 8 2 1 10 10 10 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2563 PF10817.8 AAZ34211.1 - 0.1 13.2 1.9 1.1 9.9 1.9 2.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2563) AAA_22 PF13401.6 AAZ34211.1 - 0.11 12.8 0.1 0.11 12.8 0.1 5.1 4 2 1 5 5 5 0 AAA domain RsgA_GTPase PF03193.16 AAZ34211.1 - 0.39 10.6 0.0 0.39 10.6 0.0 3.8 4 1 2 6 6 6 0 RsgA GTPase tRNA-synt_1b PF00579.25 AAZ34212.1 - 1.1e-51 175.9 0.0 1.3e-51 175.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF1508 PF07411.12 AAZ34212.1 - 0.00031 20.5 0.0 0.28 11.1 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF1508) tRNA-synt_1f PF01921.18 AAZ34212.1 - 0.026 13.4 0.0 0.17 10.8 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (K) Sigma54_activat PF00158.26 AAZ34213.1 - 4.5e-75 251.0 0.0 7.3e-75 250.3 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain FleQ PF06490.11 AAZ34213.1 - 2.7e-29 101.7 0.1 1.2e-28 99.7 0.1 2.1 2 0 0 2 2 2 1 Flagellar regulatory protein FleQ Sigma54_activ_2 PF14532.6 AAZ34213.1 - 1.4e-22 80.3 0.0 4.4e-22 78.7 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 AAZ34213.1 - 1.1e-10 41.1 1.0 1.1e-10 41.1 1.0 2.1 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 AAZ34213.1 - 4.5e-07 30.0 0.0 1.2e-06 28.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) HTH_50 PF18024.1 AAZ34213.1 - 2.6e-05 23.7 0.0 9e-05 22.0 0.0 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain AAA_16 PF13191.6 AAZ34213.1 - 4.7e-05 23.8 0.0 0.00018 21.9 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 AAZ34213.1 - 0.0019 18.5 0.0 0.41 10.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 AAZ34213.1 - 0.007 15.9 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 AAZ34213.1 - 0.01 15.2 0.1 3.2 7.1 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA PF00004.29 AAZ34213.1 - 0.011 16.1 0.1 0.082 13.3 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MTS PF05175.14 AAZ34214.1 - 0.0015 18.1 0.0 0.0028 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain N6_Mtase PF02384.16 AAZ34214.1 - 0.0084 15.4 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_31 PF13847.6 AAZ34214.1 - 0.0093 15.8 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAZ34214.1 - 0.017 15.8 0.0 0.069 13.9 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 AAZ34214.1 - 0.12 13.1 0.0 0.43 11.4 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain QRPTase_C PF01729.19 AAZ34215.1 - 3.4e-58 196.2 0.3 5.4e-58 195.5 0.3 1.3 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 AAZ34215.1 - 1.7e-27 95.3 0.0 8.7e-27 93.0 0.0 2.0 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain Ribul_P_3_epim PF00834.19 AAZ34215.1 - 0.028 13.8 0.1 0.11 11.9 0.1 1.9 2 1 0 2 2 2 0 Ribulose-phosphate 3 epimerase family DegV PF02645.16 AAZ34215.1 - 0.095 12.0 0.1 5.5 6.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein, DegV family COG1307 T6SS_VasE PF05936.12 AAZ34216.1 - 2.1e-133 445.2 0.5 2.4e-133 445.0 0.5 1.0 1 0 0 1 1 1 1 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE AAA_22 PF13401.6 AAZ34217.1 - 0.00013 22.2 1.0 0.045 14.0 0.2 3.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AAZ34217.1 - 0.0011 19.3 0.1 0.0026 18.1 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.14 AAZ34217.1 - 0.0049 16.1 0.5 0.013 14.7 0.1 2.0 2 0 0 2 2 2 1 KAP family P-loop domain AAA_28 PF13521.6 AAZ34217.1 - 0.0059 16.9 0.0 2.6 8.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 AAZ34217.1 - 0.0084 16.0 0.4 0.028 14.3 0.2 2.0 2 1 0 2 2 2 1 NACHT domain AAA_14 PF13173.6 AAZ34217.1 - 0.022 14.8 0.1 0.17 12.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 AAZ34217.1 - 0.066 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 AAZ34217.1 - 0.12 12.4 0.5 0.66 10.0 0.0 2.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) RTP1_C2 PF10304.9 AAZ34217.1 - 0.14 11.9 0.3 0.82 9.4 0.0 2.4 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 2 PhaG_MnhG_YufB PF03334.14 AAZ34218.1 - 5.4e-20 71.4 8.6 6.6e-20 71.1 8.6 1.1 1 0 0 1 1 1 1 Na+/H+ antiporter subunit DUF3537 PF12056.8 AAZ34218.1 - 0.13 11.1 0.4 7.6 5.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3537) BPD_transp_2 PF02653.16 AAZ34219.1 - 3.3e-32 111.7 37.4 4.1e-32 111.4 37.4 1.1 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component Pmp3 PF01679.17 AAZ34220.1 - 4.5e-22 78.0 10.7 5.1e-22 77.8 10.7 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Aldo_ket_red PF00248.21 AAZ34221.1 - 1.4e-36 126.2 0.0 2.3e-33 115.7 0.0 2.1 1 1 1 2 2 2 2 Aldo/keto reductase family DDE_3 PF13358.6 AAZ34222.1 - 2.4e-22 79.3 0.6 4.4e-22 78.4 0.1 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 AAZ34222.1 - 1.6e-12 47.8 3.0 1.6e-12 47.8 3.0 2.3 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 AAZ34222.1 - 3.7e-12 46.2 3.7 6.8e-11 42.1 0.4 2.9 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 AAZ34222.1 - 4.1e-09 36.3 3.1 1e-08 35.1 0.1 2.8 3 0 0 3 3 3 1 Winged helix-turn helix HTH_23 PF13384.6 AAZ34222.1 - 5.3e-08 32.4 3.3 8.8e-07 28.6 0.2 2.8 2 1 0 2 2 2 1 Homeodomain-like domain LZ_Tnp_IS481 PF13011.6 AAZ34222.1 - 4.4e-06 27.1 2.1 0.0038 17.7 0.3 2.6 1 1 1 2 2 2 2 leucine-zipper of insertion element IS481 rve PF00665.26 AAZ34222.1 - 0.0015 18.7 0.4 0.014 15.6 0.1 2.2 2 0 0 2 2 2 1 Integrase core domain Terminase_5 PF06056.12 AAZ34222.1 - 0.0069 16.3 0.4 0.31 11.0 0.0 2.8 3 0 0 3 3 3 1 Putative ATPase subunit of terminase (gpP-like) HTH_26 PF13443.6 AAZ34222.1 - 0.015 15.7 0.0 0.4 11.1 0.0 2.7 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain HTH_7 PF02796.15 AAZ34222.1 - 0.042 13.9 0.1 14 5.8 0.0 3.0 2 1 0 2 2 2 0 Helix-turn-helix domain of resolvase CTP_transf_1 PF01148.20 AAZ34223.1 - 7.8e-66 222.6 20.1 8.7e-66 222.4 20.1 1.0 1 0 0 1 1 1 1 Cytidylyltransferase family Aminotran_1_2 PF00155.21 AAZ34224.1 - 3.3e-19 69.3 0.0 4.9e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II GntR PF00392.21 AAZ34224.1 - 1.6e-14 53.3 0.0 3.7e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_Crp_2 PF13545.6 AAZ34224.1 - 0.0012 18.8 0.0 0.0037 17.2 0.0 1.9 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_24 PF13412.6 AAZ34224.1 - 0.044 13.3 0.0 0.2 11.3 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Aminotran_5 PF00266.19 AAZ34224.1 - 0.11 11.5 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V MarR PF01047.22 AAZ34224.1 - 0.13 12.2 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_36 PF13730.6 AAZ34224.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_28 PF13518.6 AAZ34225.1 - 0.0019 18.3 0.1 0.88 9.7 0.0 2.5 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_23 PF13384.6 AAZ34225.1 - 0.0098 15.7 0.1 0.27 11.1 0.0 2.8 2 1 0 2 2 2 1 Homeodomain-like domain AbiEi_4 PF13338.6 AAZ34225.1 - 0.045 13.9 1.5 0.64 10.2 0.1 3.0 3 0 0 3 3 3 0 Transcriptional regulator, AbiEi antitoxin HTH_29 PF13551.6 AAZ34225.1 - 0.13 12.3 3.4 5.1 7.2 0.1 3.2 4 0 0 4 4 4 0 Winged helix-turn helix HTH_3 PF01381.22 AAZ34225.1 - 0.15 12.1 0.1 1.8 8.7 0.0 2.4 2 1 1 3 3 3 0 Helix-turn-helix AstA PF04958.12 AAZ34226.1 - 1.3e-123 411.9 0.0 1.5e-123 411.7 0.0 1.0 1 0 0 1 1 1 1 Arginine N-succinyltransferase beta subunit HTH_Tnp_Tc3_2 PF01498.18 AAZ34227.1 - 0.014 15.6 0.0 0.024 14.9 0.0 1.3 1 0 0 1 1 1 0 Transposase DUF4096 PF13340.6 AAZ34227.1 - 0.098 12.9 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 Putative transposase of IS4/5 family (DUF4096) AA_permease PF00324.21 AAZ34228.1 - 6.3e-109 364.7 46.2 7e-109 364.6 46.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 AAZ34228.1 - 3.8e-45 154.5 51.0 4.6e-45 154.2 51.0 1.0 1 0 0 1 1 1 1 Amino acid permease Spore_permease PF03845.13 AAZ34228.1 - 4.4e-08 32.3 13.6 4.4e-08 32.3 13.6 3.2 2 2 1 3 3 3 1 Spore germination protein NAD_binding_2 PF03446.15 AAZ34229.1 - 3.2e-39 134.6 3.3 5e-39 134.0 3.3 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 AAZ34229.1 - 4.5e-37 127.0 0.1 1.1e-36 125.7 0.1 1.7 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 AAZ34229.1 - 2.2e-08 33.6 0.1 3.7e-08 32.9 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 AAZ34229.1 - 2.9e-06 27.7 0.4 6.4e-06 26.7 0.4 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 AAZ34229.1 - 4.4e-06 26.7 0.6 8.2e-06 25.8 0.6 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.12 AAZ34229.1 - 1.9e-05 24.3 0.1 3.5e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Rossmann-like PF10727.9 AAZ34229.1 - 0.0016 18.3 1.4 0.0031 17.4 1.4 1.4 1 0 0 1 1 1 1 Rossmann-like domain ApbA PF02558.16 AAZ34229.1 - 0.0056 16.3 0.1 0.01 15.5 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GFO_IDH_MocA PF01408.22 AAZ34229.1 - 0.093 13.6 0.1 0.15 12.9 0.1 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold AlaDh_PNT_C PF01262.21 AAZ34229.1 - 6.4 6.0 10.0 0.057 12.7 1.4 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain MCPsignal PF00015.21 AAZ34230.1 - 3.3e-40 137.7 24.2 3.3e-40 137.7 24.2 3.6 2 1 2 4 4 4 1 Methyl-accepting chemotaxis protein (MCP) signalling domain 4HB_MCP_1 PF12729.7 AAZ34230.1 - 4.7e-16 58.8 0.3 4.7e-16 58.8 0.3 3.0 4 1 1 5 5 5 1 Four helix bundle sensory module for signal transduction HAMP PF00672.25 AAZ34230.1 - 1.8e-07 31.4 10.7 1.3e-05 25.5 0.2 4.6 4 1 0 4 4 4 2 HAMP domain Chi-conotoxin PF16981.5 AAZ34230.1 - 0.034 14.4 0.4 0.099 12.9 0.4 1.8 1 0 0 1 1 1 0 chi-Conotoxin or t superfamily RestrictionSfiI PF11487.8 AAZ34230.1 - 0.71 9.7 2.9 0.37 10.6 0.3 1.8 2 0 0 2 2 2 0 Type II restriction enzyme SfiI FAD-oxidase_C PF02913.19 AAZ34231.1 - 4.5e-61 206.7 0.0 6e-61 206.2 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 AAZ34231.1 - 2.2e-36 124.7 0.9 3.7e-36 123.9 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain DUF4096 PF13340.6 AAZ34232.1 - 5.9e-25 87.3 0.4 1.5e-24 86.0 0.4 1.7 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1 PF01609.21 AAZ34232.1 - 5.5e-14 52.3 0.0 9.7e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AAZ34232.1 - 2.4e-08 34.2 0.1 7.4e-08 32.7 0.1 1.9 1 0 0 1 1 1 1 Transposase DDE domain HTH_Tnp_Tc3_2 PF01498.18 AAZ34232.1 - 0.063 13.5 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Transposase Acetyltransf_1 PF00583.25 AAZ34234.1 - 6.6e-15 55.4 0.0 7.7e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAZ34234.1 - 8.9e-12 45.3 0.1 1.2e-11 44.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAZ34234.1 - 1.2e-09 38.1 0.0 1.6e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AAZ34234.1 - 1.3e-05 25.2 0.0 0.00023 21.3 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAZ34234.1 - 2.9e-05 23.9 0.0 4.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein PanZ PF12568.8 AAZ34234.1 - 0.00098 18.9 0.0 0.0011 18.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_4 PF13420.7 AAZ34234.1 - 0.003 17.7 0.0 0.0038 17.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AAZ34234.1 - 0.016 15.3 0.0 0.028 14.5 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_6 PF13480.7 AAZ34234.1 - 0.04 14.1 0.1 0.048 13.8 0.1 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AAZ34234.1 - 0.07 13.8 0.0 0.075 13.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain 2-oxoacid_dh PF00198.23 AAZ34236.1 - 6.1e-83 277.8 0.1 8.7e-83 277.3 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 AAZ34236.1 - 3e-17 62.2 6.8 3.7e-17 61.9 1.4 2.6 2 1 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 AAZ34236.1 - 1.2e-16 60.8 0.6 3.6e-16 59.2 0.3 2.1 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 AAZ34236.1 - 0.019 14.8 0.0 0.055 13.3 0.0 1.8 1 0 0 1 1 1 0 Biotin-lipoyl like GCV_H PF01597.19 AAZ34236.1 - 0.11 12.3 2.3 2.6 7.9 0.2 2.8 2 1 0 2 2 2 0 Glycine cleavage H-protein DUF2868 PF11067.8 AAZ34236.1 - 0.37 10.3 3.2 0.52 9.8 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) MFS_1 PF07690.16 AAZ34237.1 - 4e-40 137.8 53.7 4e-40 137.8 53.7 3.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 AAZ34237.1 - 6.5e-05 21.7 4.5 6.5e-05 21.7 4.5 3.1 2 1 0 2 2 2 1 MFS/sugar transport protein Gp_dh_C PF02800.20 AAZ34238.1 - 3.5e-61 205.4 0.1 4.7e-61 205.0 0.1 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 AAZ34238.1 - 2.1e-37 127.5 0.0 7.2e-37 125.8 0.0 1.9 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain NAD_binding_3 PF03447.16 AAZ34238.1 - 0.0018 18.9 0.0 0.0083 16.8 0.0 2.0 1 1 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 AAZ34238.1 - 0.0063 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Semialdhyde_dhC PF02774.18 AAZ34238.1 - 0.033 14.3 0.0 0.065 13.3 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, dimerisation domain DapB_N PF01113.20 AAZ34238.1 - 0.056 13.6 0.0 0.13 12.3 0.0 1.8 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.22 AAZ34238.1 - 0.1 13.4 0.3 0.99 10.3 0.0 2.7 3 1 0 3 3 3 0 Oxidoreductase family, NAD-binding Rossmann fold Ribonuc_L-PSP PF01042.21 AAZ34239.1 - 4e-23 81.7 0.0 4.7e-23 81.5 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP FdhD-NarQ PF02634.15 AAZ34240.1 - 1.9e-63 214.4 0.0 2.1e-63 214.2 0.0 1.0 1 0 0 1 1 1 1 FdhD/NarQ family His_biosynth PF00977.21 AAZ34241.1 - 5.5e-78 261.6 0.4 6.2e-78 261.4 0.4 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Dus PF01207.17 AAZ34241.1 - 1.4e-07 31.0 0.8 0.0058 15.8 0.2 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) TMP-TENI PF02581.17 AAZ34241.1 - 1.2e-05 24.8 0.3 0.0078 15.6 0.3 2.3 2 0 0 2 2 2 2 Thiamine monophosphate synthase G3P_antiterm PF04309.12 AAZ34241.1 - 0.0018 17.7 0.4 1 8.8 0.1 2.4 2 0 0 2 2 2 2 Glycerol-3-phosphate responsive antiterminator DeoC PF01791.9 AAZ34241.1 - 0.0049 16.5 1.2 0.38 10.3 0.1 2.2 1 1 1 2 2 2 2 DeoC/LacD family aldolase NMO PF03060.15 AAZ34241.1 - 0.0055 16.1 5.4 0.0095 15.4 2.8 2.0 2 0 0 2 2 2 1 Nitronate monooxygenase DHO_dh PF01180.21 AAZ34241.1 - 0.0056 15.9 1.5 0.42 9.8 0.1 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase PcrB PF01884.17 AAZ34241.1 - 0.006 16.1 0.3 0.029 13.9 0.0 1.9 2 0 0 2 2 2 1 PcrB family IMPDH PF00478.25 AAZ34241.1 - 0.0092 15.0 3.7 0.23 10.4 1.4 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain Trp_syntA PF00290.20 AAZ34241.1 - 0.015 14.2 0.3 0.092 11.6 0.0 2.0 2 0 0 2 2 2 0 Tryptophan synthase alpha chain LysR_substrate PF03466.20 AAZ34242.1 - 4.5e-25 88.3 1.2 6.4e-25 87.7 1.2 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ34242.1 - 1.4e-16 60.1 0.2 3.7e-16 58.8 0.2 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family DUF4771 PF15995.5 AAZ34243.1 - 0.14 12.4 0.1 0.28 11.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4771) DDE_Tnp_IS1 PF03400.13 AAZ34243.1 - 0.17 12.2 0.1 10 6.5 0.0 2.2 1 1 1 2 2 2 0 IS1 transposase cobW PF02492.19 AAZ34244.1 - 1.3e-52 178.0 0.0 1.8e-52 177.5 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 AAZ34244.1 - 4.4e-19 68.2 0.0 7.1e-19 67.5 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain TsaE PF02367.17 AAZ34244.1 - 0.0035 17.3 0.1 0.0095 15.9 0.1 1.7 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 AAZ34244.1 - 0.0038 17.4 0.9 0.019 15.1 0.9 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AAZ34244.1 - 0.0053 17.3 0.1 0.08 13.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AAZ34244.1 - 0.0065 16.9 0.8 0.023 15.1 0.8 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AAZ34244.1 - 0.0089 16.3 0.0 0.026 14.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain MobB PF03205.14 AAZ34244.1 - 0.012 15.5 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.18 AAZ34244.1 - 0.013 15.3 0.1 0.023 14.4 0.1 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RsgA_GTPase PF03193.16 AAZ34244.1 - 0.028 14.3 0.0 0.37 10.7 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase CbiA PF01656.23 AAZ34244.1 - 0.04 14.0 0.0 0.088 12.9 0.0 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_28 PF13521.6 AAZ34244.1 - 0.06 13.6 0.0 0.2 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 AAZ34244.1 - 0.1 12.5 0.0 0.35 10.8 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 AAZ34244.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AAZ34244.1 - 0.13 12.7 0.0 0.27 11.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Pyr_redox PF00070.27 AAZ34245.1 - 0.057 14.0 0.0 3.9 8.1 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GLF PF03275.13 AAZ34246.1 - 4.7e-80 268.1 0.8 6.9e-80 267.6 0.8 1.2 1 0 0 1 1 1 1 UDP-galactopyranose mutase NAD_binding_8 PF13450.6 AAZ34246.1 - 2.2e-14 53.4 0.4 4.2e-14 52.5 0.4 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AAZ34246.1 - 3e-05 23.8 0.0 5.1e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 AAZ34246.1 - 0.00013 22.4 0.1 0.00033 21.2 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 AAZ34246.1 - 0.00025 21.0 0.0 0.00053 20.0 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 AAZ34246.1 - 0.00053 19.5 0.0 0.0011 18.5 0.0 1.6 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 AAZ34246.1 - 0.00079 18.7 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 AAZ34246.1 - 0.0046 16.6 0.2 0.013 15.1 0.2 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 AAZ34246.1 - 0.0073 15.4 0.1 0.012 14.7 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein TrkA_N PF02254.18 AAZ34246.1 - 0.011 16.0 0.1 0.036 14.3 0.0 1.9 2 0 0 2 2 1 0 TrkA-N domain GMC_oxred_N PF00732.19 AAZ34246.1 - 0.017 14.5 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 GMC oxidoreductase FAD_binding_3 PF01494.19 AAZ34246.1 - 0.054 12.7 0.1 0.081 12.2 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.24 AAZ34246.1 - 0.066 12.3 0.2 0.11 11.6 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Sacchrp_dh_NADP PF03435.18 AAZ34246.1 - 0.068 13.4 0.1 0.2 11.9 0.1 1.8 2 0 0 2 2 1 0 Saccharopine dehydrogenase NADP binding domain DUF1188 PF06690.11 AAZ34246.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) HI0933_like PF03486.14 AAZ34246.1 - 0.15 10.7 0.1 0.24 10.1 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.18 AAZ34246.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDI PF00996.18 AAZ34246.1 - 0.16 10.4 0.0 0.31 9.5 0.0 1.4 1 0 0 1 1 1 0 GDP dissociation inhibitor UDPG_MGDP_dh_N PF03721.14 AAZ34247.1 - 5e-61 205.5 0.0 8.1e-61 204.9 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 AAZ34247.1 - 2e-34 117.7 0.0 3.8e-34 116.8 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 AAZ34247.1 - 9.8e-31 106.3 0.0 3e-29 101.5 0.0 2.4 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 3HCDH_N PF02737.18 AAZ34247.1 - 0.00014 21.8 0.2 0.0024 17.8 0.0 2.5 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 AAZ34247.1 - 0.00017 21.3 0.0 0.00049 19.8 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 AAZ34247.1 - 0.00053 20.0 0.0 0.0023 17.9 0.0 2.1 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 AAZ34247.1 - 0.0016 19.0 0.0 4.7 7.9 0.0 3.7 3 1 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 AAZ34247.1 - 0.0047 17.3 0.0 0.4 11.1 0.0 2.8 3 0 0 3 3 3 1 Putative NAD(P)-binding NAD_binding_2 PF03446.15 AAZ34247.1 - 0.021 15.0 0.0 0.86 9.8 0.0 2.7 3 0 0 3 3 3 0 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.21 AAZ34247.1 - 0.027 13.8 0.0 0.053 12.8 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 AAZ34247.1 - 0.061 13.9 0.6 0.26 11.9 0.4 2.3 2 1 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 AAZ34247.1 - 0.11 12.7 1.1 0.35 11.1 0.1 2.4 3 0 0 3 3 3 0 TrkA-N domain Glycos_transf_1 PF00534.20 AAZ34248.1 - 3.8e-32 111.2 0.0 5.1e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAZ34248.1 - 1.2e-14 54.9 0.0 1.8e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAZ34248.1 - 1.5e-05 25.0 0.1 0.00068 19.7 0.1 2.3 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 AAZ34248.1 - 0.037 14.4 0.0 0.077 13.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 Radical_SAM_N PF08497.10 AAZ34249.1 - 3.3e-144 479.6 0.0 4.6e-144 479.2 0.0 1.2 1 0 0 1 1 1 1 Radical SAM N-terminal DUF3362 PF11842.8 AAZ34249.1 - 7.2e-51 172.4 2.0 1.6e-50 171.3 2.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3362) Radical_SAM PF04055.21 AAZ34249.1 - 1.3e-21 77.7 0.0 2.7e-21 76.7 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily B12-binding PF02310.19 AAZ34249.1 - 0.0052 16.8 0.0 0.86 9.7 0.0 2.6 2 0 0 2 2 2 2 B12 binding domain Acyltransferase PF01553.21 AAZ34251.1 - 8e-21 74.1 0.0 1.2e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase DUF808 PF05661.12 AAZ34251.1 - 0.083 11.9 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF808) FAD_binding_5 PF00941.21 AAZ34252.1 - 1.2e-50 171.6 0.0 2.3e-50 170.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 AAZ34252.1 - 7.1e-35 119.3 0.4 2.8e-34 117.4 0.5 2.0 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.20 AAZ34252.1 - 5.1e-29 100.1 1.8 1.3e-28 98.8 1.8 1.8 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 AAZ34252.1 - 6.1e-07 29.3 1.5 6.7e-05 22.8 0.2 2.5 2 0 0 2 2 2 2 2Fe-2S iron-sulfur cluster binding domain DUF2235 PF09994.9 AAZ34253.1 - 3.2e-20 72.7 0.0 2.8e-11 43.3 0.0 3.0 2 1 1 3 3 3 2 Uncharacterized alpha/beta hydrolase domain (DUF2235) PyocinActivator PF11112.8 AAZ34254.1 - 2.7e-23 81.8 0.0 3.2e-23 81.6 0.0 1.0 1 0 0 1 1 1 1 Pyocin activator protein PrtN FixS PF03597.15 AAZ34255.1 - 1.5e-22 79.0 2.2 1.9e-22 78.7 2.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase maturation protein cbb3-type DUF3981 PF13139.6 AAZ34255.1 - 0.065 13.6 0.2 0.073 13.4 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3981) DUF1127 PF06568.11 AAZ34257.1 - 5.6e-14 51.6 4.5 6.9e-14 51.3 4.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1127) DUF5596 PF18082.1 AAZ34257.1 - 0.0027 17.5 0.0 0.003 17.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5596) SAM_2 PF07647.17 AAZ34257.1 - 0.1 12.7 1.1 0.47 10.6 0.1 2.0 1 1 1 2 2 2 0 SAM domain (Sterile alpha motif) Nucleic_acid_bd PF13820.6 AAZ34257.1 - 0.17 11.7 0.3 0.22 11.3 0.3 1.1 1 0 0 1 1 1 0 Putative nucleic acid-binding region CtaG_Cox11 PF04442.14 AAZ34258.1 - 5.7e-39 133.5 0.0 6.8e-39 133.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Peripla_BP_4 PF13407.6 AAZ34259.1 - 1.9e-28 99.8 0.0 5.8e-27 94.9 0.0 2.0 1 1 1 2 2 2 1 Periplasmic binding protein domain LacI PF00356.21 AAZ34259.1 - 2.4e-08 33.6 0.5 4.8e-08 32.7 0.5 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_1 PF00532.21 AAZ34259.1 - 0.00092 18.7 0.0 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family HTH_31 PF13560.6 AAZ34259.1 - 0.0079 16.5 0.1 0.024 15.0 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 AAZ34259.1 - 0.011 15.1 0.2 0.029 13.8 0.2 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 ThiC_Rad_SAM PF01964.18 AAZ34259.1 - 0.048 12.4 0.0 0.073 11.8 0.0 1.2 1 0 0 1 1 1 0 Radical SAM ThiC family 2-Hacid_dh_C PF02826.19 AAZ34261.1 - 7.6e-44 149.2 0.0 9.7e-44 148.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 AAZ34261.1 - 9.6e-05 22.8 0.0 0.00016 22.1 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding NAD_binding_2 PF03446.15 AAZ34261.1 - 0.00026 21.2 0.0 0.00058 20.1 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 AAZ34261.1 - 0.00041 20.4 0.0 0.0013 18.8 0.0 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 AAZ34261.1 - 0.0049 17.4 0.0 0.0088 16.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Oxidored_nitro PF00148.19 AAZ34261.1 - 0.0072 15.1 0.0 0.011 14.5 0.0 1.3 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase Pyr_redox_2 PF07992.14 AAZ34261.1 - 0.0096 15.2 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 AAZ34261.1 - 0.021 15.1 0.2 1.9 8.7 0.2 2.5 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ThiF PF00899.21 AAZ34261.1 - 0.023 14.1 0.2 0.063 12.6 0.2 1.7 1 1 1 2 2 2 0 ThiF family ELFV_dehydrog PF00208.21 AAZ34261.1 - 0.024 14.4 0.0 0.036 13.8 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase GFO_IDH_MocA PF01408.22 AAZ34261.1 - 0.12 13.2 0.0 0.21 12.4 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold FAD_binding_3 PF01494.19 AAZ34261.1 - 0.13 11.4 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain AdoHcyase_NAD PF00670.21 AAZ34261.1 - 0.19 11.8 0.0 0.34 11.0 0.0 1.4 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain cobW PF02492.19 AAZ34262.1 - 2.5e-59 199.8 0.0 3.2e-59 199.5 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 AAZ34262.1 - 3.8e-17 62.0 0.1 8.2e-17 60.9 0.1 1.6 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_16 PF13191.6 AAZ34262.1 - 0.0011 19.4 0.7 0.0042 17.5 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 AAZ34262.1 - 0.0051 17.1 0.1 0.024 14.9 0.0 2.1 3 0 0 3 3 2 1 AAA domain Viral_helicase1 PF01443.18 AAZ34262.1 - 0.014 15.1 0.1 0.023 14.4 0.1 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 AAZ34262.1 - 0.017 14.9 0.5 0.23 11.2 0.1 2.2 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 AAZ34262.1 - 0.027 14.5 0.1 0.055 13.5 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TrwB_AAD_bind PF10412.9 AAZ34262.1 - 0.027 13.4 0.0 0.042 12.8 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain T2SSE PF00437.20 AAZ34262.1 - 0.038 13.1 0.1 0.093 11.8 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein ATPase_2 PF01637.18 AAZ34262.1 - 0.05 13.5 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 AAZ34262.1 - 0.065 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 AAZ34262.1 - 0.086 11.8 0.9 1.4 7.8 0.0 2.5 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 AAZ34262.1 - 0.099 12.5 0.0 1.8 8.5 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase NACHT PF05729.12 AAZ34262.1 - 0.099 12.6 0.2 0.25 11.2 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_29 PF13555.6 AAZ34262.1 - 0.15 11.8 0.5 0.44 10.3 0.1 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain MobB PF03205.14 AAZ34262.1 - 0.38 10.6 0.1 0.38 10.6 0.1 2.6 2 1 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B Glyco_transf_9 PF01075.17 AAZ34263.1 - 5.3e-87 291.3 0.0 6.4e-87 291.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 9 (heptosyltransferase) PS_pyruv_trans PF04230.13 AAZ34263.1 - 0.0078 16.2 0.0 0.41 10.5 0.0 2.1 2 0 0 2 2 2 2 Polysaccharide pyruvyl transferase ssDBP PF17878.1 AAZ34264.1 - 1.4e-12 47.7 0.1 1.7e-12 47.4 0.1 1.1 1 0 0 1 1 1 1 Single-stranded DNA-binding protein CTX_RstB PF07459.11 AAZ34264.1 - 0.0078 16.4 0.1 0.031 14.5 0.0 1.8 2 0 0 2 2 2 1 CTX phage RstB protein BNR_2 PF13088.6 AAZ34265.1 - 6.8e-82 274.9 0.0 8.5e-82 274.6 0.0 1.1 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 AAZ34265.1 - 0.00086 19.0 1.7 1.2 9.4 0.4 3.4 3 0 0 3 3 3 2 BNR/Asp-box repeat Glucos_trans_II PF14264.6 AAZ34266.1 - 4.6e-22 78.7 19.9 7.2e-22 78.1 19.9 1.3 1 0 0 1 1 1 1 Glucosyl transferase GtrII CheW PF01584.19 AAZ34267.1 - 1.9e-24 85.9 0.4 3e-24 85.2 0.4 1.4 1 0 0 1 1 1 1 CheW-like domain Hpt PF01627.23 AAZ34267.1 - 3.5e-18 65.6 0.5 3.5e-18 65.6 0.5 3.0 4 1 0 4 4 4 1 Hpt domain HATPase_c PF02518.26 AAZ34267.1 - 4.6e-18 65.8 0.1 1.1e-17 64.6 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase H-kinase_dim PF02895.14 AAZ34267.1 - 6.6e-14 52.1 2.6 3.2e-13 49.9 2.7 2.2 2 0 0 2 2 2 1 Signal transducing histidine kinase, homodimeric domain SHOCT PF09851.9 AAZ34267.1 - 4.1e-05 23.2 9.9 0.23 11.2 0.2 4.5 4 0 0 4 4 4 3 Short C-terminal domain HATPase_c_3 PF13589.6 AAZ34267.1 - 0.0027 17.6 0.1 0.0057 16.5 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1018 PF06252.12 AAZ34267.1 - 0.0087 17.0 0.1 13 6.8 0.0 4.0 1 1 3 4 4 4 1 Protein of unknown function (DUF1018) Herpes_UL25 PF01499.16 AAZ34267.1 - 0.19 10.2 0.7 0.41 9.1 0.0 1.7 2 0 0 2 2 2 0 Herpesvirus UL25 family ORF_12_N PF18042.1 AAZ34267.1 - 1 9.8 5.5 4.8 7.7 0.1 3.6 2 1 1 3 3 3 0 ORF 12 gene product N-terminal UPF0184 PF03670.13 AAZ34267.1 - 2.3 8.7 4.7 2 8.8 0.0 3.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) Bac_surface_Ag PF01103.23 AAZ34268.1 - 4e-34 118.6 0.4 6.3e-34 117.9 0.4 1.2 1 0 0 1 1 1 1 Surface antigen POTRA_TamA_1 PF17243.2 AAZ34268.1 - 2.1e-17 63.0 0.5 4.4e-16 58.7 0.3 2.4 2 0 0 2 2 2 1 POTRA domain TamA domain 1 POTRA PF07244.15 AAZ34268.1 - 2.4e-15 56.9 0.0 1.6e-06 28.5 0.0 3.4 3 0 0 3 3 3 3 Surface antigen variable number repeat AI-2E_transport PF01594.16 AAZ34269.1 - 8e-47 160.0 28.6 9.1e-47 159.8 28.6 1.0 1 0 0 1 1 1 1 AI-2E family transporter Abhydrolase_1 PF00561.20 AAZ34271.1 - 9.6e-29 100.8 0.1 6.8e-28 98.0 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAZ34271.1 - 3.5e-14 53.9 5.7 4.2e-14 53.7 5.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAZ34271.1 - 1.4e-11 44.2 0.0 2.4e-11 43.4 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 AAZ34271.1 - 0.0012 17.7 0.0 0.0016 17.2 0.0 1.1 1 0 0 1 1 1 1 Ndr family Abhydrolase_4 PF08386.10 AAZ34271.1 - 0.0025 17.9 0.0 0.0077 16.3 0.0 1.7 2 0 0 2 2 2 1 TAP-like protein HisKA PF00512.25 AAZ34272.1 - 2.3e-15 56.4 1.6 5.9e-15 55.1 0.1 2.5 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HATPase_c PF02518.26 AAZ34272.1 - 4.4e-15 56.2 0.1 7.9e-15 55.3 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.25 AAZ34272.1 - 2e-07 31.0 0.0 1.5e-06 28.2 0.0 2.4 3 0 0 3 3 3 1 PAS fold PAS_4 PF08448.10 AAZ34272.1 - 9.5e-07 29.1 0.0 2.3e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 AAZ34272.1 - 0.0016 18.4 0.1 0.0048 16.9 0.0 1.9 2 0 0 2 2 2 1 PAS domain HATPase_c_5 PF14501.6 AAZ34272.1 - 0.0025 17.7 0.0 0.0051 16.7 0.0 1.6 1 0 0 1 1 1 1 GHKL domain PAS_9 PF13426.7 AAZ34272.1 - 0.006 16.8 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 PAS domain DUF1688 PF07958.11 AAZ34272.1 - 0.036 12.8 0.2 0.056 12.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1688) UpxZ PF06603.11 AAZ34272.1 - 0.099 12.9 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 UpxZ family of transcription anti-terminator antagonists HATPase_c_3 PF13589.6 AAZ34272.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RRM_1 PF00076.22 AAZ34273.1 - 0.12 12.2 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Na_H_Exchanger PF00999.21 AAZ34274.1 - 2.2e-53 181.4 51.4 3e-53 181.0 51.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TrkA_C PF02080.21 AAZ34274.1 - 2.6e-13 49.6 0.0 4.9e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 TrkA-C domain CorC_HlyC PF03471.17 AAZ34274.1 - 2.1e-10 40.4 0.0 4.7e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Transporter associated domain Maf PF02545.14 AAZ34275.1 - 2.4e-56 190.2 0.0 2.7e-56 190.0 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein Vut_1 PF02592.15 AAZ34276.1 - 3.2e-05 24.3 11.5 0.0001 22.7 11.4 2.0 1 1 0 1 1 1 1 Putative vitamin uptake transporter TraQ PF09679.10 AAZ34276.1 - 0.062 13.2 1.5 1.1 9.2 0.1 2.5 1 1 0 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) LapA_dom PF06305.11 AAZ34276.1 - 0.11 12.3 6.6 0.22 11.3 0.6 2.8 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Phosphodiest PF01663.22 AAZ34277.1 - 1.1e-10 41.6 0.1 3.6e-05 23.5 0.0 2.3 2 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DDE_Tnp_1 PF01609.21 AAZ34278.1 - 2.3e-17 63.3 0.8 2.8e-17 63.1 0.8 1.0 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_6 PF13751.6 AAZ34278.1 - 1e-07 32.2 0.6 1.4e-07 31.8 0.6 1.3 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 AAZ34278.1 - 0.00015 21.4 0.1 0.00022 20.9 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1_2 PF13586.6 AAZ34278.1 - 0.0023 18.3 0.8 0.0034 17.7 0.8 1.2 1 0 0 1 1 1 1 Transposase DDE domain DUF4096 PF13340.6 AAZ34279.1 - 3.8e-25 87.9 0.4 9.5e-25 86.6 0.4 1.7 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1 PF01609.21 AAZ34279.1 - 1.8e-14 53.9 0.0 3e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AAZ34279.1 - 5.5e-10 39.5 0.2 1.3e-09 38.3 0.2 1.7 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 AAZ34279.1 - 0.19 11.7 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain RNase_PH PF01138.21 AAZ34280.1 - 3.8e-45 153.6 0.0 3e-22 79.5 0.0 2.6 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 PNPase PF03726.14 AAZ34280.1 - 6.6e-23 81.0 0.1 1.6e-22 79.8 0.1 1.7 1 0 0 1 1 1 1 Polyribonucleotide nucleotidyltransferase, RNA binding domain RNase_PH_C PF03725.15 AAZ34280.1 - 7.3e-20 70.8 1.2 3.3e-11 43.0 0.0 2.6 2 0 0 2 2 2 2 3' exoribonuclease family, domain 2 S1 PF00575.23 AAZ34280.1 - 2.5e-16 59.8 3.1 2.5e-16 59.8 3.1 2.2 2 0 0 2 2 2 1 S1 RNA binding domain KH_1 PF00013.29 AAZ34280.1 - 8.5e-13 47.9 2.6 2.7e-12 46.3 1.5 2.5 2 0 0 2 2 2 1 KH domain KH_2 PF07650.17 AAZ34280.1 - 0.0069 16.2 0.1 0.027 14.3 0.1 2.0 1 0 0 1 1 1 1 KH domain S1_2 PF13509.6 AAZ34280.1 - 0.011 15.8 1.2 0.092 12.8 0.4 2.9 2 1 0 2 2 2 0 S1 domain Transposase_mut PF00872.18 AAZ34281.1 - 3.3e-116 388.3 0.0 4.1e-116 388.0 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ34281.1 - 7.7e-05 23.0 0.0 0.00021 21.6 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain PIN PF01850.21 AAZ34282.1 - 0.00068 20.1 0.0 0.00089 19.8 0.0 1.2 1 0 0 1 1 1 1 PIN domain CDP-OH_P_transf PF01066.21 AAZ34283.1 - 1.2e-13 51.6 1.5 1.2e-13 51.6 1.5 2.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase CD225 PF04505.12 AAZ34283.1 - 0.0021 18.1 1.3 0.0062 16.7 1.3 1.8 1 0 0 1 1 1 1 Interferon-induced transmembrane protein DUF2976 PF11190.8 AAZ34283.1 - 0.044 13.6 6.1 0.041 13.7 3.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2976) PsbT PF01405.17 AAZ34283.1 - 0.054 13.3 2.5 0.18 11.6 2.5 1.9 1 0 0 1 1 1 0 Photosystem II reaction centre T protein Polysacc_synt_C PF14667.6 AAZ34283.1 - 5.8 7.0 15.8 0.31 11.1 6.1 2.7 2 1 1 3 3 3 0 Polysaccharide biosynthesis C-terminal domain TetR_N PF00440.23 AAZ34284.1 - 2e-09 37.1 0.0 4e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family Zot PF05707.12 AAZ34285.1 - 1.2e-51 175.2 0.0 1.5e-51 174.8 0.0 1.1 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Methyltransf_24 PF13578.6 AAZ34285.1 - 0.00088 20.3 0.0 0.002 19.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Sigma54_activat PF00158.26 AAZ34287.1 - 1.2e-65 220.3 0.0 1.7e-65 219.8 0.0 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain HTH_50 PF18024.1 AAZ34287.1 - 4e-21 74.4 0.1 7.9e-21 73.4 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma54_activ_2 PF14532.6 AAZ34287.1 - 4.3e-21 75.5 0.0 3.2e-20 72.6 0.0 2.4 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_5 PF07728.14 AAZ34287.1 - 2.9e-05 24.1 0.0 0.00016 21.7 0.0 2.1 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 AAZ34287.1 - 0.00024 20.6 0.3 0.023 14.1 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI PAS PF00989.25 AAZ34287.1 - 0.0013 18.7 0.0 0.0039 17.2 0.0 1.9 1 0 0 1 1 1 1 PAS fold ACT PF01842.25 AAZ34287.1 - 0.0091 15.8 0.0 0.023 14.5 0.0 1.7 1 0 0 1 1 1 1 ACT domain PAS_8 PF13188.7 AAZ34287.1 - 0.0098 15.9 0.0 0.029 14.4 0.0 1.8 1 0 0 1 1 1 1 PAS domain AAA PF00004.29 AAZ34287.1 - 0.011 16.1 0.0 0.022 15.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 AAZ34287.1 - 0.018 15.2 0.0 0.03 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) PAS_4 PF08448.10 AAZ34287.1 - 0.058 13.7 0.0 0.31 11.3 0.0 2.3 1 0 0 1 1 1 0 PAS fold HTH_38 PF13936.6 AAZ34287.1 - 0.063 13.0 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Beta-lactamase PF00144.24 AAZ34288.1 - 7.7e-78 262.0 3.3 9.2e-78 261.8 3.3 1.0 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 AAZ34288.1 - 0.031 13.9 0.1 0.59 9.7 0.0 2.2 2 0 0 2 2 2 0 Beta-lactamase enzyme family BNR_2 PF13088.6 AAZ34289.1 - 8e-68 228.7 0.4 9.3e-68 228.5 0.4 1.0 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 AAZ34289.1 - 2.9e-07 29.5 10.8 0.55 10.4 0.2 4.8 4 0 0 4 4 4 4 BNR/Asp-box repeat Glyco_hydro_43 PF04616.14 AAZ34289.1 - 0.00011 21.7 0.0 0.00019 20.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Sortilin-Vps10 PF15902.5 AAZ34289.1 - 0.00026 19.9 0.0 0.019 13.8 0.0 2.9 3 0 0 3 3 3 1 Sortilin, neurotensin receptor 3, BPD_transp_1 PF00528.22 AAZ34290.1 - 1.9e-14 53.8 19.7 1.9e-14 53.8 19.7 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF2790 PF10976.8 AAZ34291.1 - 2.8e-33 113.8 0.8 3.2e-33 113.6 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2790) YkuD PF03734.14 AAZ34292.1 - 6.3e-21 75.3 0.0 9.1e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain Ldt_C PF17969.1 AAZ34292.1 - 0.0045 17.7 0.0 0.0081 16.9 0.0 1.4 1 0 0 1 1 1 1 L,D-transpeptidase C-terminal domain Semialdhyde_dh PF01118.24 AAZ34293.1 - 3.4e-39 134.0 0.0 5.7e-39 133.3 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.18 AAZ34293.1 - 6.4e-17 62.2 0.0 1.4e-16 61.1 0.0 1.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, dimerisation domain F420_oxidored PF03807.17 AAZ34293.1 - 2.3e-05 24.9 0.0 4.5e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.22 AAZ34293.1 - 0.0018 19.1 0.0 0.0033 18.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Gp_dh_C PF02800.20 AAZ34293.1 - 0.028 14.0 0.0 0.06 12.9 0.0 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DapB_N PF01113.20 AAZ34293.1 - 0.033 14.3 0.0 0.055 13.6 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus KR PF08659.10 AAZ34293.1 - 0.035 14.0 0.0 0.062 13.2 0.0 1.5 1 0 0 1 1 1 0 KR domain Sacchrp_dh_NADP PF03435.18 AAZ34293.1 - 0.11 12.7 0.0 0.38 11.0 0.0 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 AAZ34293.1 - 0.12 11.8 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ADH_N PF08240.12 AAZ34294.1 - 6.7e-23 80.7 1.3 7.9e-23 80.4 0.2 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AAZ34294.1 - 2.9e-22 79.0 0.1 5.4e-22 78.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AAZ34294.1 - 1.5e-05 26.0 0.0 3.1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 AAZ34294.1 - 2.1e-05 24.1 0.0 4.6e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus Met_10 PF02475.16 AAZ34294.1 - 0.0044 16.8 0.0 0.0087 15.8 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein MinC_C PF03775.16 AAZ34294.1 - 0.044 13.8 1.4 0.63 10.1 0.5 2.2 2 0 0 2 2 2 0 Septum formation inhibitor MinC, C-terminal domain Mur_ligase_C PF02875.21 AAZ34294.1 - 0.12 12.6 0.0 18 5.7 0.0 2.4 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain CLLAC PF15675.5 AAZ34294.1 - 0.45 10.1 2.5 0.85 9.2 2.5 1.4 1 0 0 1 1 1 0 CLLAC-motif containing domain Glycos_transf_N PF04413.16 AAZ34296.1 - 2.1e-66 222.9 0.3 7.7e-66 221.1 0.0 1.8 2 0 0 2 2 2 1 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) IL5 PF02025.15 AAZ34296.1 - 0.0036 17.6 0.0 0.11 12.7 0.0 2.2 2 0 0 2 2 2 1 Interleukin 5 Glycos_transf_1 PF00534.20 AAZ34296.1 - 0.031 13.8 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferases group 1 Epimerase_2 PF02350.19 AAZ34296.1 - 0.053 12.4 0.0 0.079 11.8 0.0 1.3 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase Glyco_trans_4_4 PF13579.6 AAZ34296.1 - 0.081 13.4 14.5 0.032 14.7 7.4 2.8 2 1 0 2 2 2 0 Glycosyl transferase 4-like domain Guanylate_kin PF00625.21 AAZ34297.1 - 2.4e-52 177.3 0.0 3e-52 177.0 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.6 AAZ34297.1 - 0.0001 22.5 0.3 0.00054 20.1 0.1 2.1 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 AAZ34297.1 - 0.00023 21.7 0.0 0.00041 20.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AAZ34297.1 - 0.0012 19.1 0.2 0.0029 17.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AAZ34297.1 - 0.0016 18.4 0.1 0.0047 16.8 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 AAZ34297.1 - 0.0021 18.5 0.6 0.0068 16.8 0.6 1.9 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 AAZ34297.1 - 0.0043 17.6 0.5 0.011 16.2 0.5 1.9 1 1 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.23 AAZ34297.1 - 0.0049 17.0 0.0 0.0065 16.5 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 AAZ34297.1 - 0.011 16.0 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 AAZ34297.1 - 0.028 14.9 1.7 0.088 13.3 1.7 1.9 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 AAZ34297.1 - 0.029 14.7 0.7 0.11 12.8 0.1 2.0 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 AAZ34297.1 - 0.056 13.9 0.2 0.11 12.9 0.0 1.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 AAZ34297.1 - 0.073 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF1289 PF06945.13 AAZ34298.1 - 7.5e-18 64.1 1.1 9.1e-18 63.8 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1289) Fer4_15 PF13459.6 AAZ34298.1 - 0.013 16.2 0.3 0.016 15.9 0.3 1.2 1 0 0 1 1 1 0 4Fe-4S single cluster domain DUF1284 PF06935.11 AAZ34298.1 - 0.03 14.8 0.5 0.031 14.7 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1284) Fer4_6 PF12837.7 AAZ34298.1 - 4 7.7 6.8 0.45 10.7 1.3 2.0 1 1 1 2 2 2 0 4Fe-4S binding domain MetW PF07021.12 AAZ34299.1 - 4.1e-97 323.4 0.0 4.6e-97 323.2 0.0 1.0 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_11 PF08241.12 AAZ34299.1 - 5.2e-13 49.5 0.0 9.2e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAZ34299.1 - 2.3e-10 40.6 0.0 3.4e-10 40.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAZ34299.1 - 2.3e-10 41.0 0.1 4.1e-10 40.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAZ34299.1 - 1e-08 35.1 0.0 1.3e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAZ34299.1 - 2.2e-07 31.5 0.2 4.6e-07 30.5 0.2 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AAZ34299.1 - 0.013 15.1 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.7 AAZ34299.1 - 0.014 15.3 0.0 0.021 14.7 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 AAZ34299.1 - 0.13 11.3 0.0 0.26 10.4 0.0 1.4 2 0 0 2 2 2 0 DREV methyltransferase PrmA PF06325.13 AAZ34299.1 - 0.14 11.5 0.1 0.19 11.1 0.1 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_8 PF05148.15 AAZ34299.1 - 0.16 11.8 0.0 0.25 11.2 0.0 1.3 1 1 0 1 1 1 0 Hypothetical methyltransferase CoA_trans PF01144.23 AAZ34300.1 - 3.6e-43 147.5 0.5 4.1e-43 147.3 0.5 1.0 1 0 0 1 1 1 1 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 AAZ34300.1 - 8.4e-06 25.8 0.0 1e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain HATPase_c PF02518.26 AAZ34301.1 - 9.4e-20 71.2 0.4 2.9e-19 69.6 0.3 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAZ34301.1 - 7e-13 48.4 0.3 3e-12 46.4 0.3 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 AAZ34301.1 - 8e-06 25.7 0.0 1.7e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 GHKL domain RsbRD_N PF14361.6 AAZ34301.1 - 0.00017 22.2 1.7 0.00084 20.0 1.5 2.3 2 1 0 2 2 2 1 RsbT co-antagonist protein rsbRD N-terminal domain HATPase_c_2 PF13581.6 AAZ34301.1 - 0.022 14.7 2.9 0.24 11.4 0.0 3.1 3 0 0 3 3 3 0 Histidine kinase-like ATPase domain Transket_pyr PF02779.24 AAZ34305.1 - 1.4e-35 122.6 0.2 2e-35 122.0 0.2 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 AAZ34305.1 - 1.9e-29 102.1 0.3 1.1e-28 99.5 0.1 2.0 2 0 0 2 2 2 1 Transketolase, C-terminal domain PFOR_II PF17147.4 AAZ34305.1 - 0.015 15.6 0.0 0.029 14.7 0.0 1.5 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II Epimerase PF01370.21 AAZ34306.1 - 1.1e-61 208.4 0.0 1.3e-61 208.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AAZ34306.1 - 2.7e-51 174.9 0.0 3.1e-51 174.7 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 AAZ34306.1 - 5.8e-24 84.6 0.0 9.2e-24 83.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 AAZ34306.1 - 1.7e-19 70.5 0.0 2.2e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 AAZ34306.1 - 3.5e-16 59.2 0.0 2.2e-15 56.6 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 AAZ34306.1 - 6.1e-12 45.3 0.0 1.3e-10 40.9 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 AAZ34306.1 - 7.9e-12 44.9 0.0 8.7e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 AAZ34306.1 - 1.5e-11 44.3 0.1 7.7e-09 35.4 0.2 2.2 2 0 0 2 2 2 2 NmrA-like family KR PF08659.10 AAZ34306.1 - 3.4e-05 23.9 1.2 9.5e-05 22.4 1.2 1.7 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 AAZ34306.1 - 0.002 17.6 0.2 0.0035 16.8 0.2 1.4 1 1 0 1 1 1 1 short chain dehydrogenase Lipoprotein_9 PF03180.14 AAZ34307.1 - 1.6e-70 236.9 0.0 1.8e-70 236.8 0.0 1.0 1 0 0 1 1 1 1 NLPA lipoprotein PepSY_2 PF13670.6 AAZ34307.1 - 0.043 13.8 0.6 0.043 13.8 0.6 2.2 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain BPD_transp_1 PF00528.22 AAZ34308.1 - 5.7e-29 101.2 13.1 5.7e-29 101.2 13.1 2.1 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 AAZ34308.1 - 1.1e-08 34.9 0.7 1.1e-08 34.9 0.7 3.0 3 0 0 3 3 3 1 N-terminal TM domain of oligopeptide transport permease C Clostridium_P47 PF06597.11 AAZ34308.1 - 0.89 8.2 3.4 1.2 7.8 3.4 1.3 1 0 0 1 1 1 0 Clostridium P-47 protein Glu_cys_ligase PF04262.14 AAZ34309.1 - 5.6e-164 545.2 0.0 9.8e-164 544.4 0.0 1.4 2 0 0 2 2 2 1 Glutamate-cysteine ligase PDE4_UCR PF18100.1 AAZ34309.1 - 0.06 14.0 0.4 0.17 12.6 0.2 1.9 2 0 0 2 2 2 0 Phosphodiesterase 4 upstream conserved regions (UCR) TPR_19 PF14559.6 AAZ34311.1 - 1.7e-10 41.3 9.6 2.7e-05 24.6 0.1 4.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 AAZ34311.1 - 0.00079 19.4 0.9 1.8 9.0 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 AAZ34311.1 - 0.0009 19.9 1.7 0.058 14.2 0.2 4.6 4 0 0 4 4 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 AAZ34311.1 - 0.0013 19.2 9.5 0.43 11.3 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat ATG16 PF08614.11 AAZ34311.1 - 0.0022 18.3 2.2 0.0022 18.3 2.2 3.2 4 0 0 4 4 4 1 Autophagy protein 16 (ATG16) TPR_10 PF13374.6 AAZ34311.1 - 0.0033 17.2 1.3 0.12 12.3 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 AAZ34311.1 - 0.0055 16.7 0.2 1 9.7 0.1 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat LysM PF01476.20 AAZ34311.1 - 0.0058 16.7 0.1 0.012 15.7 0.1 1.5 1 0 0 1 1 1 1 LysM domain TPR_11 PF13414.6 AAZ34311.1 - 0.024 14.3 0.0 0.066 12.9 0.0 1.8 1 0 0 1 1 1 0 TPR repeat Alkyl_sulf_dimr PF14863.6 AAZ34311.1 - 0.084 13.3 1.0 11 6.5 0.4 3.1 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation Cytochrom_B562 PF07361.11 AAZ34311.1 - 0.12 13.0 9.2 0.56 10.9 0.3 3.5 3 0 0 3 3 2 0 Cytochrome b562 VPDSG-CTERM PF18205.1 AAZ34311.1 - 4.1 7.3 9.2 9.6 6.1 9.2 1.6 1 0 0 1 1 1 0 VPDSG-CTERM motif OEP PF02321.18 AAZ34312.1 - 3.3e-45 154.2 24.4 3.6e-23 82.4 13.0 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein LPAM_1 PF08139.12 AAZ34312.1 - 0.038 14.5 1.0 0.11 13.1 1.0 1.8 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site MCPsignal PF00015.21 AAZ34313.1 - 3.5e-43 147.4 36.9 1.1e-40 139.2 24.0 2.9 1 1 2 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain sCache_2 PF17200.4 AAZ34313.1 - 3e-27 95.4 0.0 3e-27 95.4 0.0 4.0 4 1 1 5 5 4 1 Single Cache domain 2 dCache_2 PF08269.11 AAZ34313.1 - 6.7e-23 81.3 3.7 9.4e-23 80.8 0.0 2.6 3 1 1 4 4 4 1 Cache domain HAMP PF00672.25 AAZ34313.1 - 5.2e-14 52.4 14.1 8.3e-12 45.3 0.2 5.7 7 0 0 7 7 4 1 HAMP domain Cache_3-Cache_2 PF17201.4 AAZ34313.1 - 1.2e-06 28.1 0.0 1.2e-06 28.1 0.0 3.4 3 1 0 4 4 4 1 Cache 3/Cache 2 fusion domain Laminin_I PF06008.14 AAZ34313.1 - 0.00094 19.0 2.0 0.00094 19.0 2.0 3.1 3 1 0 3 3 2 1 Laminin Domain I DUF948 PF06103.11 AAZ34313.1 - 0.006 16.8 32.2 0.026 14.8 1.6 6.2 3 1 2 6 6 5 1 Bacterial protein of unknown function (DUF948) FPP PF05911.11 AAZ34313.1 - 0.0067 14.7 8.0 0.2 9.8 1.4 2.1 2 0 0 2 2 2 2 Filament-like plant protein, long coiled-coil Syntaxin_2 PF14523.6 AAZ34313.1 - 0.012 15.9 11.6 0.55 10.6 0.1 4.7 3 1 1 4 4 4 0 Syntaxin-like protein BAR_2 PF10455.9 AAZ34313.1 - 0.038 13.1 1.9 0.049 12.8 0.4 1.8 1 1 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking AAA_13 PF13166.6 AAZ34313.1 - 0.073 11.7 8.7 0.63 8.6 2.4 2.1 1 1 0 2 2 2 0 AAA domain TolA_bind_tri PF16331.5 AAZ34313.1 - 0.08 13.0 0.5 0.08 13.0 0.5 3.5 3 0 0 3 3 3 0 TolA binding protein trimerisation Fib_alpha PF08702.10 AAZ34313.1 - 0.091 12.9 8.1 0.58 10.3 1.2 3.7 2 2 1 3 3 3 0 Fibrinogen alpha/beta chain family CAP_N PF01213.19 AAZ34313.1 - 0.099 12.1 7.0 3.2 7.2 0.1 2.3 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Syntaxin PF00804.25 AAZ34313.1 - 0.1 12.3 12.2 0.98 9.0 1.7 3.0 2 1 0 2 2 2 0 Syntaxin WXG100 PF06013.12 AAZ34313.1 - 0.18 12.1 24.4 0.87 9.9 4.8 4.8 2 2 1 3 3 3 0 Proteins of 100 residues with WXG COG2 PF06148.11 AAZ34313.1 - 0.21 11.7 9.2 2.6 8.1 0.0 4.4 4 1 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3450 PF11932.8 AAZ34313.1 - 0.27 10.5 17.6 0.31 10.3 6.2 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) DUF4200 PF13863.6 AAZ34313.1 - 0.29 11.5 3.0 14 6.1 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) ZapB PF06005.12 AAZ34313.1 - 0.57 10.7 8.5 1.1 9.7 0.1 4.3 4 2 0 4 4 4 0 Cell division protein ZapB AIP3 PF03915.13 AAZ34313.1 - 0.68 9.0 14.3 0.17 11.0 3.6 2.3 1 1 1 2 2 2 0 Actin interacting protein 3 APG6_N PF17675.1 AAZ34313.1 - 0.83 10.2 3.6 3.9 8.0 0.6 2.5 2 0 0 2 2 2 0 Apg6 coiled-coil region Mod_r PF07200.13 AAZ34313.1 - 1 9.4 5.5 5.5 7.1 0.1 3.4 1 1 3 4 4 4 0 Modifier of rudimentary (Mod(r)) protein UPF0242 PF06785.11 AAZ34313.1 - 1.2 9.2 3.6 2.3 8.3 0.1 2.8 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus ISG65-75 PF11727.8 AAZ34313.1 - 1.3 8.2 13.8 0.09 12.0 2.1 2.4 2 0 0 2 2 2 0 Invariant surface glycoprotein DUF2894 PF11445.8 AAZ34313.1 - 1.5 9.3 14.1 0.38 11.2 3.6 2.7 3 0 0 3 3 2 0 Protein of unknown function (DUF2894) YabA PF06156.13 AAZ34313.1 - 1.5 9.5 3.8 48 4.7 0.1 3.5 3 0 0 3 3 3 0 Initiation control protein YabA DUF16 PF01519.16 AAZ34313.1 - 1.7 9.2 10.1 6.4 7.3 0.9 3.8 3 2 1 4 4 3 0 Protein of unknown function DUF16 DUF4795 PF16043.5 AAZ34313.1 - 2.4 7.7 9.0 2.4e+02 1.2 9.1 2.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) ADIP PF11559.8 AAZ34313.1 - 2.4 8.2 10.5 1.8 8.7 1.3 3.1 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding BLOC1_2 PF10046.9 AAZ34313.1 - 3.3 8.1 11.5 11 6.4 0.2 4.5 3 2 1 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 V_ATPase_I PF01496.19 AAZ34313.1 - 4.1 5.2 6.1 32 2.3 6.1 2.1 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family PHA_synth_III_E PF09712.10 AAZ34313.1 - 5.6 6.0 10.1 1.6 7.7 2.1 2.2 1 1 0 2 2 2 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) HisKA_3 PF07730.13 AAZ34313.1 - 6 7.5 25.6 0.77 10.3 0.8 4.8 5 1 1 6 6 4 0 Histidine kinase TraI PF07057.11 AAZ34313.1 - 6.5 6.9 6.6 1.1 9.4 1.9 2.2 3 0 0 3 3 1 0 DNA helicase TraI Lectin_N PF03954.14 AAZ34313.1 - 7.7 6.3 8.6 1.7 8.4 1.3 3.2 2 2 0 2 2 2 0 Hepatic lectin, N-terminal domain TPR_MLP1_2 PF07926.12 AAZ34313.1 - 8 6.5 21.2 0.53 10.4 1.7 3.7 3 1 0 4 4 4 0 TPR/MLP1/MLP2-like protein Laminin_II PF06009.12 AAZ34313.1 - 8.8 6.3 21.9 8 6.5 3.4 4.0 3 2 1 4 4 3 0 Laminin Domain II ADH_zinc_N PF00107.26 AAZ34314.1 - 4.6e-25 88.1 0.1 8e-25 87.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AAZ34314.1 - 3.1e-14 54.2 0.0 5.6e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AAZ34314.1 - 8.4e-10 38.5 0.0 5.4e-09 35.9 0.0 2.2 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain SLT_2 PF13406.6 AAZ34315.1 - 2.3e-99 332.3 0.8 2.9e-99 332.0 0.8 1.1 1 0 0 1 1 1 1 Transglycosylase SLT domain PG_binding_1 PF01471.18 AAZ34315.1 - 1.8e-12 47.3 0.1 5.3e-12 45.8 0.1 1.9 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Glucosaminidase PF01832.20 AAZ34315.1 - 0.00015 22.2 0.1 0.00033 21.1 0.1 1.7 1 1 0 1 1 1 1 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase PG_binding_3 PF09374.10 AAZ34315.1 - 0.012 15.9 0.1 0.036 14.3 0.1 1.8 1 0 0 1 1 1 0 Predicted Peptidoglycan domain ABC_trans_N PF14510.6 AAZ34315.1 - 0.057 14.0 0.0 0.13 12.9 0.0 1.6 1 0 0 1 1 1 0 ABC-transporter N-terminal Neisseria_PilC PF05567.11 AAZ34316.1 - 2.1e-49 168.5 9.7 5.4e-49 167.1 9.7 1.7 1 0 0 1 1 1 1 Neisseria PilC beta-propeller domain PQQ PF01011.21 AAZ34316.1 - 0.066 13.2 0.1 14 5.8 0.0 3.8 4 0 0 4 4 4 0 PQQ enzyme repeat Glyco_trans_1_2 PF13524.6 AAZ34317.1 - 4.1e-09 36.7 0.1 4.1e-08 33.5 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAZ34317.1 - 0.001 19.5 0.0 0.0023 18.4 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 PPK2 PF03976.14 AAZ34318.1 - 3.8e-143 474.8 9.0 5.9e-92 307.3 5.6 2.0 2 0 0 2 2 2 2 Polyphosphate kinase 2 (PPK2) Thymidylate_kin PF02223.17 AAZ34318.1 - 0.0011 18.7 0.1 0.42 10.3 0.0 3.2 3 0 0 3 3 3 1 Thymidylate kinase SRP54_N PF02881.19 AAZ34318.1 - 0.0095 16.1 0.1 0.037 14.3 0.1 2.1 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain Zeta_toxin PF06414.12 AAZ34318.1 - 0.019 14.2 0.1 0.33 10.2 0.0 2.6 3 0 0 3 3 3 0 Zeta toxin AAA_18 PF13238.6 AAZ34318.1 - 0.04 14.5 0.0 16 6.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain GSHPx PF00255.19 AAZ34318.1 - 0.18 11.4 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione peroxidase GDP_Man_Dehyd PF16363.5 AAZ34319.1 - 2.6e-137 457.7 0.0 3e-137 457.5 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 AAZ34319.1 - 3.9e-66 222.9 0.0 4.9e-66 222.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 AAZ34319.1 - 1e-07 31.3 0.0 1.5e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain ketoacyl-synt PF00109.26 AAZ34320.1 - 2.1e-56 191.3 0.3 3.7e-56 190.5 0.0 1.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 AAZ34320.1 - 1.4e-36 125.1 0.2 2.7e-36 124.2 0.2 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 AAZ34320.1 - 2e-07 31.5 0.0 4.2e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 AAZ34320.1 - 0.013 14.9 0.1 0.026 13.9 0.1 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain TadZ_N PF16968.5 AAZ34321.1 - 2e-47 160.2 1.8 4.2e-47 159.1 1.8 1.5 1 0 0 1 1 1 1 Pilus assembly protein TadZ N-terminal UPF0114 PF03350.16 AAZ34322.1 - 2.4e-27 95.5 4.7 2.4e-27 95.5 4.7 1.3 2 0 0 2 2 2 1 Uncharacterized protein family, UPF0114 DUF3169 PF11368.8 AAZ34322.1 - 0.025 14.1 5.7 0.026 14.0 5.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) SBP_bac_6 PF13343.6 AAZ34323.1 - 4.7e-50 170.3 1.0 6.4e-50 169.8 1.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 AAZ34323.1 - 4.7e-22 79.1 2.5 6.4e-22 78.7 2.5 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 AAZ34323.1 - 9.4e-17 61.5 1.7 1.5e-16 60.9 1.7 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AAZ34323.1 - 5.8e-09 36.3 9.5 8.3e-09 35.8 9.5 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein PE_PPE_C PF12484.8 AAZ34323.1 - 0.059 14.3 1.6 1.5 9.8 0.0 2.8 2 0 0 2 2 2 0 Polymorphic PE/PPE proteins C terminal Acetyltransf_1 PF00583.25 AAZ34324.1 - 1.7e-10 41.2 0.0 2e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAZ34324.1 - 1.7e-07 31.5 0.0 2.6e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAZ34324.1 - 1.9e-07 31.1 0.0 2.4e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 AAZ34324.1 - 0.05 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_CG PF14542.6 AAZ34324.1 - 0.16 12.1 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase ABC_tran PF00005.27 AAZ34327.1 - 4e-32 111.6 0.0 7.2e-32 110.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter TOBE_2 PF08402.10 AAZ34327.1 - 1e-09 38.4 0.0 2.4e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 TOBE domain AAA_21 PF13304.6 AAZ34327.1 - 2.4e-09 37.5 0.1 0.00088 19.2 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system OB_MalK PF17912.1 AAZ34327.1 - 5.5e-08 33.5 0.0 1.7e-07 32.0 0.0 1.9 1 0 0 1 1 1 1 MalK OB fold domain TOBE PF03459.17 AAZ34327.1 - 0.00021 21.5 0.0 0.00058 20.1 0.0 1.7 2 0 0 2 2 1 1 TOBE domain SMC_N PF02463.19 AAZ34327.1 - 0.00036 20.0 0.0 0.36 10.2 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 AAZ34327.1 - 0.0011 18.9 0.1 0.0027 17.6 0.1 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 AAZ34327.1 - 0.0022 18.5 0.1 0.004 17.7 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAZ34327.1 - 0.0037 17.7 0.3 0.0082 16.5 0.3 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AAZ34327.1 - 0.0095 15.7 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AAZ34327.1 - 0.013 15.8 0.1 0.028 14.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AAZ34327.1 - 0.026 14.1 0.3 0.2 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 AAZ34327.1 - 0.032 14.2 0.1 0.053 13.4 0.1 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain ATPase_2 PF01637.18 AAZ34327.1 - 0.035 14.0 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 AAZ34327.1 - 0.037 13.8 0.0 0.29 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 AAZ34327.1 - 0.069 13.1 0.5 0.3 11.0 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 AAZ34327.1 - 0.095 13.1 0.1 0.4 11.1 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 AAZ34327.1 - 0.11 12.6 0.4 0.71 10.0 0.4 2.1 1 1 0 1 1 1 0 AAA domain Adeno_IVa2 PF02456.15 AAZ34327.1 - 0.14 10.9 0.0 0.23 10.2 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_24 PF13479.6 AAZ34327.1 - 0.17 11.6 0.2 4.9 6.8 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 AAZ34327.1 - 0.17 12.1 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.6 AAZ34327.1 - 0.29 9.7 0.0 1.4 7.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain ATP_bind_3 PF01171.20 AAZ34328.1 - 6.6e-54 182.4 0.0 8.8e-54 182.0 0.0 1.2 1 0 0 1 1 1 1 PP-loop family TilS_C PF11734.8 AAZ34328.1 - 1.3e-16 59.8 0.1 2.3e-16 59.0 0.1 1.4 1 0 0 1 1 1 1 TilS substrate C-terminal domain TilS PF09179.11 AAZ34328.1 - 1.2e-13 51.3 7.7 1.2e-13 51.3 7.7 3.1 3 0 0 3 3 3 1 TilS substrate binding domain Asn_synthase PF00733.21 AAZ34328.1 - 0.024 14.3 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase PAPS_reduct PF01507.19 AAZ34328.1 - 0.047 13.7 0.0 0.11 12.6 0.0 1.8 1 1 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family QueC PF06508.13 AAZ34328.1 - 0.073 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC CcmB PF03379.13 AAZ34329.1 - 2.9e-83 278.6 30.5 3.4e-83 278.4 30.5 1.0 1 0 0 1 1 1 1 CcmB protein ABC2_membrane PF01061.24 AAZ34329.1 - 1.5e-06 27.8 9.9 1.5e-06 27.8 9.9 1.3 1 1 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 AAZ34329.1 - 7.9 5.5 19.1 1.2 8.2 14.4 1.8 1 1 1 2 2 2 0 ABC-2 family transporter protein 3HCDH_N PF02737.18 AAZ34330.1 - 2.7e-62 209.8 0.5 6.4e-62 208.6 0.5 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 AAZ34330.1 - 9.3e-39 133.2 0.3 1.6e-38 132.5 0.3 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 AAZ34330.1 - 4.5e-30 104.1 0.5 3.9e-26 91.5 0.3 2.9 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 AAZ34330.1 - 1.8e-21 77.0 0.0 3.2e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase NAD_binding_2 PF03446.15 AAZ34330.1 - 0.033 14.4 0.2 0.074 13.2 0.2 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase FUR PF01475.19 AAZ34331.1 - 1.3e-10 41.5 0.0 2.6e-10 40.5 0.0 1.5 2 0 0 2 2 2 1 Ferric uptake regulator family Penicillinase_R PF03965.16 AAZ34331.1 - 0.013 15.9 0.0 0.02 15.2 0.0 1.2 1 0 0 1 1 1 0 Penicillinase repressor PadR PF03551.14 AAZ34331.1 - 0.063 13.2 0.0 0.095 12.7 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF1641 PF07849.11 AAZ34331.1 - 0.1 12.5 0.1 0.32 10.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1641) TBPIP PF07106.13 AAZ34331.1 - 0.14 12.1 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 TBPIP/Hop2 winged helix domain DUF2514 PF10721.9 AAZ34332.1 - 8.1e-48 162.5 20.8 9.6e-48 162.2 20.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2514) PhoD PF09423.10 AAZ34333.1 - 1.4e-104 349.9 0.7 1.8e-104 349.5 0.7 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 AAZ34333.1 - 1.5e-29 102.4 0.0 2.8e-29 101.5 0.0 1.5 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 AAZ34333.1 - 0.007 16.9 0.0 0.031 14.8 0.0 2.0 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 AAZ34333.1 - 0.071 13.6 0.0 0.28 11.6 0.0 2.0 2 1 1 3 3 3 0 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AAZ34333.1 - 0.19 11.9 0.0 0.39 10.9 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain UBA2_C PF16195.5 AAZ34334.1 - 0.013 16.1 0.9 0.013 16.1 0.9 1.1 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus DUF3545 PF12065.8 AAZ34334.1 - 0.046 13.7 1.0 0.057 13.5 1.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3545) Acyl-CoA_dh_2 PF08028.11 AAZ34335.1 - 2.6e-20 73.0 4.9 2.6e-20 73.0 4.9 2.3 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_1 PF00441.24 AAZ34335.1 - 8.9e-10 39.0 1.2 1.6e-09 38.1 1.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 AAZ34335.1 - 6e-09 36.0 0.0 1.3e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 AAZ34335.1 - 2.7e-08 34.4 0.1 8.1e-08 32.9 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain DNA_pol3_delta2 PF13177.6 AAZ34336.1 - 1.1e-45 155.4 0.0 2e-45 154.5 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DNApol3-delta_C PF09115.10 AAZ34336.1 - 3.6e-07 30.7 4.7 3.6e-07 30.7 4.7 1.8 2 0 0 2 2 2 1 DNA polymerase III, delta subunit, C terminal AAA PF00004.29 AAZ34336.1 - 9e-05 22.9 0.0 0.00026 21.4 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AAZ34336.1 - 0.00099 19.5 0.1 0.0018 18.7 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AAZ34336.1 - 0.013 15.8 0.5 0.46 10.8 0.0 3.1 2 1 1 3 3 3 0 AAA domain Mg_chelatase PF01078.21 AAZ34336.1 - 0.02 14.3 0.1 0.04 13.3 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 AAZ34336.1 - 0.052 13.5 0.1 0.46 10.5 0.0 2.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 AAZ34336.1 - 0.083 12.8 1.4 0.62 10.0 0.0 2.5 2 1 1 3 3 3 0 NACHT domain Pantoate_ligase PF02569.15 AAZ34337.1 - 8.4e-104 346.5 0.0 9.5e-104 346.3 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase DJ-1_PfpI PF01965.24 AAZ34338.1 - 2.6e-07 30.6 0.1 6.3e-07 29.3 0.0 1.7 1 1 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 AAZ34338.1 - 0.049 13.4 0.0 0.07 12.9 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferase class-I HATPase_c PF02518.26 AAZ34339.1 - 1.4e-19 70.6 0.0 2.7e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAZ34339.1 - 6.6e-14 51.7 1.4 5e-13 48.9 0.7 2.4 1 1 1 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 AAZ34339.1 - 9.2e-08 31.9 0.0 2.5e-07 30.5 0.0 1.7 2 0 0 2 2 2 1 GHKL domain HAMP PF00672.25 AAZ34339.1 - 4.8e-05 23.7 0.0 0.00013 22.3 0.0 1.8 1 0 0 1 1 1 1 HAMP domain HATPase_c_2 PF13581.6 AAZ34339.1 - 0.0021 18.0 0.0 0.0044 17.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain USP7_C2 PF14533.6 AAZ34339.1 - 0.13 11.9 0.0 12 5.5 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-specific protease C-terminal DUF1249 PF06853.12 AAZ34340.1 - 1.9e-42 143.9 0.0 2.3e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1249) zinc_ribbon_16 PF17034.5 AAZ34340.1 - 0.13 12.5 0.1 0.21 11.8 0.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon like family LysR_substrate PF03466.20 AAZ34341.1 - 3.9e-36 124.4 0.0 5.1e-36 124.0 0.0 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ34341.1 - 7.6e-19 67.4 3.1 2.5e-18 65.8 3.3 1.8 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family DUF3458_C PF17432.2 AAZ34342.1 - 1.7e-120 402.2 10.6 1.7e-120 402.2 10.6 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3458_C) ARM repeats Peptidase_M1 PF01433.20 AAZ34342.1 - 1.8e-52 178.1 0.8 3.1e-52 177.3 0.8 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain DUF3458 PF11940.8 AAZ34342.1 - 9.1e-30 103.0 0.1 3e-29 101.3 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3458) Ig-like fold Peptidase_M1_N PF17900.1 AAZ34342.1 - 1.5e-15 57.9 0.0 2.6e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 AAZ34342.1 - 0.003 17.9 0.4 0.047 14.1 0.4 2.7 1 1 0 1 1 1 1 M61 glycyl aminopeptidase DUF2268 PF10026.9 AAZ34342.1 - 0.09 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) H2TH PF06831.14 AAZ34342.1 - 0.12 12.3 0.0 0.39 10.7 0.0 1.8 1 0 0 1 1 1 0 Formamidopyrimidine-DNA glycosylase H2TH domain LysR_substrate PF03466.20 AAZ34343.1 - 8.6e-56 188.6 0.3 8.6e-56 188.6 0.3 1.5 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ34343.1 - 1.5e-16 60.1 2.9 1.5e-16 60.1 2.9 2.4 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family PBP_like PF12727.7 AAZ34343.1 - 7.3e-09 35.0 0.0 1.1e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 PBP superfamily domain MarR_2 PF12802.7 AAZ34343.1 - 0.33 10.9 2.1 0.58 10.1 1.0 2.1 2 0 0 2 2 2 0 MarR family HATPase_c PF02518.26 AAZ34344.1 - 2.1e-20 73.3 0.0 3.5e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 AAZ34344.1 - 4.4e-15 55.7 0.1 9.5e-15 54.7 0.1 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AAZ34344.1 - 2.5e-08 34.1 0.1 6.2e-08 32.9 0.1 1.7 1 0 0 1 1 1 1 PAS fold HisKA PF00512.25 AAZ34344.1 - 6.7e-08 32.5 0.1 6.7e-08 32.5 0.1 2.7 2 1 1 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 AAZ34344.1 - 5.3e-06 26.6 0.0 1e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 AAZ34344.1 - 0.00026 20.9 0.0 0.0006 19.8 0.0 1.7 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.6 AAZ34344.1 - 0.00032 20.5 0.0 0.00064 19.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AAZ34344.1 - 0.13 12.2 0.0 0.32 10.9 0.0 1.8 1 0 0 1 1 1 0 GHKL domain NusA_N PF08529.11 AAZ34345.1 - 2e-35 121.8 4.1 2e-35 121.8 4.1 1.9 2 0 0 2 2 2 1 NusA N-terminal domain KH_5 PF13184.6 AAZ34345.1 - 3.6e-28 97.4 2.9 1.6e-26 92.2 0.1 3.6 4 0 0 4 4 4 1 NusA-like KH domain HHH_5 PF14520.6 AAZ34345.1 - 3.3e-12 46.8 6.6 8.5e-09 35.9 1.6 3.2 3 0 0 3 3 3 2 Helix-hairpin-helix domain S1 PF00575.23 AAZ34345.1 - 7.4e-08 32.6 0.3 3.2e-07 30.6 0.3 2.2 1 0 0 1 1 1 1 S1 RNA binding domain KH_2 PF07650.17 AAZ34345.1 - 0.0032 17.3 1.1 0.06 13.2 0.0 3.1 3 0 0 3 3 3 1 KH domain HHH_2 PF12826.7 AAZ34345.1 - 0.024 14.8 1.9 0.45 10.6 0.1 2.8 1 1 2 3 3 3 0 Helix-hairpin-helix motif RNA_pol_A_CTD PF03118.15 AAZ34345.1 - 0.085 12.6 0.5 0.41 10.4 0.1 2.2 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain DUF2187 PF09953.9 AAZ34345.1 - 0.11 12.5 0.5 0.37 10.8 0.2 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2187) PKS_DE PF18369.1 AAZ34345.1 - 0.28 11.8 1.8 1.3 9.6 0.3 2.7 2 0 0 2 2 2 0 Polyketide synthase dimerisation element domain Rhodanese PF00581.20 AAZ34346.1 - 2.7e-12 47.1 0.0 3.7e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain DPBB_1 PF03330.18 AAZ34347.1 - 1.5e-24 86.1 0.0 2.3e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 Lytic transglycolase HATPase_c_2 PF13581.6 AAZ34347.1 - 0.04 13.9 0.0 0.073 13.0 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain LPAM_1 PF08139.12 AAZ34347.1 - 0.11 13.1 4.4 0.24 12.0 4.4 1.6 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site NusG PF02357.19 AAZ34348.1 - 3.3e-25 88.4 0.0 4.6e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 Transcription termination factor nusG DHOR PF06537.11 AAZ34349.1 - 3.1e-141 471.4 0.0 4e-141 471.0 0.0 1.1 1 0 0 1 1 1 1 Di-haem oxidoreductase, putative peroxidase Cytochrom_C PF00034.21 AAZ34349.1 - 2.4e-09 38.2 0.0 7.4e-05 23.8 0.0 3.0 2 1 0 2 2 2 2 Cytochrome c Cytochrome_CBB3 PF13442.6 AAZ34349.1 - 1.2e-05 25.5 0.1 0.24 11.7 0.0 3.3 2 1 0 2 2 2 2 Cytochrome C oxidase, cbb3-type, subunit III Cytochrome_C7 PF14522.6 AAZ34349.1 - 0.029 14.4 0.1 3.1 7.9 0.0 2.3 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c Cytochrom_C550 PF14495.6 AAZ34349.1 - 0.07 12.8 0.2 3.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Cytochrome c-550 domain Haem_bd PF14376.6 AAZ34349.1 - 0.14 12.1 0.0 2.9 7.8 0.0 2.4 2 0 0 2 2 2 0 Haem-binding domain FixO PF02433.15 AAZ34349.1 - 0.22 10.9 0.1 0.74 9.2 0.0 1.8 2 0 0 2 2 2 0 Cytochrome C oxidase, mono-heme subunit/FixO PAS_3 PF08447.12 AAZ34350.1 - 1.4e-22 79.8 0.0 2.7e-13 50.0 0.0 3.6 3 0 0 3 3 3 2 PAS fold HATPase_c PF02518.26 AAZ34350.1 - 3.7e-18 66.1 0.0 8.2e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_4 PF08448.10 AAZ34350.1 - 7.5e-12 45.5 5.6 4.4e-06 26.9 0.1 4.7 4 1 1 5 5 5 3 PAS fold PAS PF00989.25 AAZ34350.1 - 3.8e-07 30.1 0.0 0.012 15.6 0.0 3.5 3 0 0 3 3 3 2 PAS fold HisKA PF00512.25 AAZ34350.1 - 4e-07 30.0 0.6 2.8e-06 27.3 0.1 2.6 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 AAZ34350.1 - 2.4e-05 24.5 0.0 2.3 8.5 0.0 4.2 4 1 0 4 4 4 2 PAS domain HATPase_c_3 PF13589.6 AAZ34350.1 - 0.011 15.6 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Thioesterase PF00975.20 AAZ34351.1 - 8.8e-46 156.9 0.5 9.9e-46 156.7 0.5 1.0 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 AAZ34351.1 - 6.1e-08 33.5 5.0 7.8e-08 33.2 5.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAZ34351.1 - 4.4e-07 29.4 0.0 0.0015 17.8 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 AAZ34351.1 - 1.3e-05 25.1 0.1 2.8e-05 24.1 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 AAZ34351.1 - 0.0018 17.9 0.1 0.44 10.1 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold LCAT PF02450.15 AAZ34351.1 - 0.03 13.5 0.0 0.037 13.2 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Lipase_3 PF01764.25 AAZ34351.1 - 0.058 13.3 0.0 0.089 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_9 PF10081.9 AAZ34351.1 - 0.082 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family LIDHydrolase PF10230.9 AAZ34351.1 - 0.089 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Chlorophyllase2 PF12740.7 AAZ34351.1 - 0.13 11.2 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme FSH1 PF03959.13 AAZ34351.1 - 0.18 11.5 0.0 0.3 10.7 0.0 1.4 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Peptidase_C13 PF01650.18 AAZ34352.1 - 2.4e-43 148.5 0.0 1.4e-35 123.0 0.0 2.1 1 1 1 2 2 2 2 Peptidase C13 family MORN PF02493.20 AAZ34352.1 - 1.4e-34 115.9 49.6 0.00063 19.5 0.1 12.1 12 0 0 12 12 12 11 MORN repeat Peptidase_C14 PF00656.22 AAZ34352.1 - 9.4e-07 29.0 0.0 1.6e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Aminotran_5 PF00266.19 AAZ34354.1 - 8.8e-32 110.5 0.0 1.2e-31 110.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V TAT_signal PF10518.9 AAZ34354.1 - 8.3 6.4 10.4 0.89 9.5 3.3 2.4 1 1 1 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence Oxidored_q4 PF00507.19 AAZ34355.1 - 4e-34 116.7 0.8 5.4e-34 116.3 0.8 1.2 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 EptA_B_N PF08019.12 AAZ34355.1 - 0.044 13.7 2.5 0.12 12.2 0.9 1.9 2 0 0 2 2 2 0 Phosphoethanolamine transferase EptA/EptB K_trans PF02705.16 AAZ34355.1 - 0.67 8.4 4.5 0.66 8.4 4.2 1.2 1 1 0 1 1 1 0 K+ potassium transporter T6SS_VipA PF05591.12 AAZ34356.1 - 8.5e-62 207.6 0.6 9.7e-62 207.4 0.6 1.0 1 0 0 1 1 1 1 Type VI secretion system, VipA, VC_A0107 or Hcp2 ABC_tran PF00005.27 AAZ34357.1 - 2e-32 112.6 0.0 2.6e-32 112.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAZ34357.1 - 2.7e-11 43.8 0.1 2.2e-05 24.4 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system BCA_ABC_TP_C PF12399.8 AAZ34357.1 - 0.00019 21.3 0.0 0.00036 20.4 0.0 1.5 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_29 PF13555.6 AAZ34357.1 - 0.00022 20.9 0.0 0.00054 19.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AAZ34357.1 - 0.00054 19.9 0.1 0.0024 17.8 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 AAZ34357.1 - 0.0045 17.4 0.1 0.0082 16.5 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 AAZ34357.1 - 0.0082 15.6 0.3 0.87 9.0 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 AAZ34357.1 - 0.0086 16.2 0.1 0.023 14.8 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.6 AAZ34357.1 - 0.0086 16.6 0.1 0.02 15.4 0.1 1.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 AAZ34357.1 - 0.012 15.2 0.2 0.068 12.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 AAZ34357.1 - 0.013 14.3 0.1 4.4 6.0 0.0 2.8 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_15 PF13175.6 AAZ34357.1 - 0.022 14.5 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 AAZ34357.1 - 0.035 14.4 0.4 0.25 11.6 0.4 2.0 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AAZ34357.1 - 0.05 13.8 0.3 0.17 12.0 0.2 2.0 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 AAZ34357.1 - 0.05 13.7 0.0 0.2 11.7 0.0 1.8 1 1 0 1 1 1 0 Dynamin family SbcCD_C PF13558.6 AAZ34357.1 - 0.061 13.6 0.1 0.42 10.9 0.1 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.6 AAZ34357.1 - 0.07 11.8 0.0 0.09 11.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain Arm-DNA-bind_3 PF13356.6 AAZ34358.1 - 6.1e-19 68.2 0.3 1.6e-18 66.9 0.3 1.7 1 0 0 1 1 1 1 Arm DNA-binding domain Phage_integrase PF00589.22 AAZ34358.1 - 4.3e-14 52.7 0.8 9.9e-14 51.5 0.1 1.9 2 0 0 2 2 2 1 Phage integrase family GST_N PF02798.20 AAZ34360.1 - 1.3e-13 51.0 0.0 2.7e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 AAZ34360.1 - 4.7e-12 46.2 0.0 8.6e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AAZ34360.1 - 2.2e-06 27.8 0.0 3.7e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 AAZ34360.1 - 2.4e-06 27.7 0.0 3.6e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 AAZ34360.1 - 0.00015 21.7 0.0 0.00035 20.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 AAZ34360.1 - 0.00084 20.0 0.0 0.0015 19.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 AAZ34360.1 - 0.11 12.8 0.0 0.32 11.3 0.0 1.7 2 0 0 2 2 2 0 Outer mitochondrial membrane transport complex protein Aminotran_1_2 PF00155.21 AAZ34361.1 - 2.8e-69 234.0 0.0 3.3e-69 233.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 AAZ34361.1 - 4.1e-05 23.1 0.0 6.1e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_MocR PF12897.7 AAZ34361.1 - 0.065 12.0 0.0 0.095 11.5 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase Cys_Met_Meta_PP PF01053.20 AAZ34361.1 - 0.16 10.5 0.0 1.8 7.0 0.0 2.2 1 1 1 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Rho_RNA_bind PF07497.12 AAZ34363.1 - 1.5e-32 111.2 0.0 2.7e-32 110.4 0.0 1.4 1 0 0 1 1 1 1 Rho termination factor, RNA-binding domain ATP-synt_ab PF00006.25 AAZ34363.1 - 2.2e-24 86.3 0.1 3.9e-24 85.5 0.0 1.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Rho_N PF07498.12 AAZ34363.1 - 2.3e-17 62.7 1.5 7.4e-17 61.0 0.9 2.1 2 0 0 2 2 2 1 Rho termination factor, N-terminal domain OB_RNB PF08206.11 AAZ34363.1 - 0.00089 18.9 0.0 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease B OB domain AAA_25 PF13481.6 AAZ34363.1 - 0.0044 16.6 0.0 0.013 15.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 AAZ34363.1 - 0.015 15.2 0.0 0.04 13.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 AAZ34363.1 - 0.018 15.3 0.0 0.047 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 AAZ34363.1 - 0.035 14.5 0.0 0.091 13.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PS_Dcarbxylase PF02666.15 AAZ34364.1 - 1.3e-59 201.2 0.0 1.7e-59 200.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Rhodanese PF00581.20 AAZ34364.1 - 3.6e-34 117.5 0.0 1.1e-17 64.5 0.0 2.4 2 0 0 2 2 2 2 Rhodanese-like domain PapD_N PF00345.20 AAZ34365.1 - 1.3e-37 128.5 0.3 1.7e-37 128.1 0.3 1.2 1 0 0 1 1 1 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain PapD_C PF02753.17 AAZ34365.1 - 3.5e-15 56.1 0.2 1.9e-14 53.8 0.0 2.3 3 0 0 3 3 3 1 Pili assembly chaperone PapD, C-terminal domain Pribosyltran PF00156.27 AAZ34366.1 - 5.8e-07 29.2 0.0 8.5e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_3 PF15610.6 AAZ34366.1 - 8.1e-07 28.5 0.0 1.1e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 PRTase ComF-like PRTase_2 PF15609.6 AAZ34366.1 - 0.032 13.7 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase OpcA_G6PD_assem PF10128.9 AAZ34366.1 - 0.062 12.8 0.1 0.081 12.4 0.1 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase subunit Hydrolase_4 PF12146.8 AAZ34367.1 - 1.6e-11 43.9 0.4 2.6e-10 40.0 0.4 2.1 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AAZ34367.1 - 1e-10 41.7 0.8 3.3e-05 23.7 0.6 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAZ34367.1 - 1.2e-08 35.9 12.7 5.6e-08 33.6 10.3 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 AAZ34367.1 - 2.3e-05 24.4 0.0 4.3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Ser_hydrolase PF06821.13 AAZ34367.1 - 0.00043 20.2 0.0 0.0018 18.1 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase Peptidase_S24 PF00717.23 AAZ34369.1 - 1.7e-11 43.9 0.0 2.2e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase S24-like DRTGG PF07085.12 AAZ34369.1 - 0.094 12.5 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 DRTGG domain BPD_transp_1 PF00528.22 AAZ34370.1 - 9.1e-11 41.8 17.9 9.1e-11 41.8 17.9 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF3290 PF11694.8 AAZ34370.1 - 0.97 9.4 3.8 0.66 9.9 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3290) STAS_2 PF13466.6 AAZ34371.1 - 2e-19 69.7 1.0 2.4e-19 69.5 1.0 1.1 1 0 0 1 1 1 1 STAS domain STAS PF01740.21 AAZ34371.1 - 2.5e-06 27.1 0.0 2.7e-06 27.0 0.0 1.0 1 0 0 1 1 1 1 STAS domain ABC_tran PF00005.27 AAZ34372.1 - 4.3e-35 121.2 0.0 5.6e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAZ34372.1 - 1.2e-09 38.5 1.6 5.8e-05 23.0 0.3 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAZ34372.1 - 2.7e-05 23.7 0.1 0.032 13.6 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AAZ34372.1 - 6.1e-05 23.5 1.4 0.00043 20.7 0.9 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 AAZ34372.1 - 0.00032 20.4 0.2 0.0012 18.6 0.1 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_15 PF13175.6 AAZ34372.1 - 0.0023 17.7 0.3 0.011 15.5 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 AAZ34372.1 - 0.011 15.6 0.1 0.023 14.6 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 AAZ34372.1 - 0.014 15.9 0.0 0.021 15.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AAZ34372.1 - 0.015 15.6 1.6 0.11 12.8 1.6 2.5 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 AAZ34372.1 - 0.016 15.2 0.1 0.17 11.9 0.1 2.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 AAZ34372.1 - 0.044 13.9 0.7 0.095 12.9 0.6 1.8 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 AAZ34372.1 - 0.044 13.1 0.1 0.077 12.4 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 AAZ34372.1 - 0.05 13.5 0.2 0.12 12.3 0.2 1.6 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 AAZ34372.1 - 0.052 14.0 0.0 0.4 11.1 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.23 AAZ34372.1 - 0.09 12.8 0.2 0.15 12.1 0.1 1.4 1 1 0 1 1 1 0 Dynamin family AAA_30 PF13604.6 AAZ34372.1 - 0.098 12.4 0.9 0.2 11.3 0.9 1.8 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 AAZ34372.1 - 0.11 12.8 0.0 1.8 8.8 0.0 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.9 AAZ34372.1 - 0.15 10.8 0.0 4.7 5.9 0.1 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_28 PF13521.6 AAZ34372.1 - 0.16 12.2 0.2 0.36 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 AAZ34372.1 - 0.18 12.4 0.0 0.31 11.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 AAZ34372.1 - 0.2 11.7 0.0 0.6 10.2 0.0 1.7 1 1 1 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 AAZ34372.1 - 0.24 11.5 0.3 0.58 10.3 0.2 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.6 AAZ34373.1 - 1e-25 90.9 0.0 1.2e-25 90.6 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAZ34373.1 - 0.07 13.5 0.0 0.14 12.6 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 AAZ34373.1 - 0.11 13.1 0.0 0.17 12.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 AAZ34373.1 - 0.18 11.7 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea SBP_bac_11 PF13531.6 AAZ34374.1 - 1.6e-41 142.6 0.0 2.3e-41 142.0 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AAZ34374.1 - 1e-14 55.2 10.6 3.1e-14 53.6 5.5 2.1 2 0 0 2 2 2 2 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AAZ34374.1 - 6.9e-07 28.9 0.6 1.6e-06 27.7 0.4 1.5 1 1 1 2 2 2 1 Bacterial extracellular solute-binding protein PBP_like PF12727.7 AAZ34374.1 - 7.2e-05 22.0 0.0 0.00015 21.0 0.0 1.6 1 1 0 1 1 1 1 PBP superfamily domain BPD_transp_1 PF00528.22 AAZ34375.1 - 1.5e-13 50.9 16.4 1.8e-13 50.6 16.4 1.1 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component HSP20 PF00011.21 AAZ34376.1 - 5.5e-15 55.4 0.1 7.2e-15 55.0 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 AAZ34376.1 - 0.019 14.5 0.1 0.059 12.9 0.1 1.8 1 1 0 1 1 1 0 HSP20-like domain found in ArsA CSD PF00313.22 AAZ34377.1 - 1.8e-26 91.7 0.6 2e-26 91.6 0.6 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 AAZ34377.1 - 0.00062 19.4 1.1 0.001 18.7 1.1 1.6 1 1 0 1 1 1 1 Ribonuclease B OB domain SIS PF01380.22 AAZ34378.1 - 1.2e-23 83.4 0.2 1.9e-23 82.8 0.2 1.3 1 0 0 1 1 1 1 SIS domain HTH_6 PF01418.17 AAZ34378.1 - 4.9e-13 48.9 0.0 1.2e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain, rpiR family TFIIS_M PF07500.14 AAZ34378.1 - 0.013 16.0 0.1 0.17 12.4 0.0 2.2 1 1 0 2 2 2 0 Transcription factor S-II (TFIIS), central domain BLM10_mid PF16507.5 AAZ34378.1 - 0.093 11.4 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Proteasome-substrate-size regulator, mid region Polysacc_deac_2 PF04748.13 AAZ34378.1 - 0.14 11.4 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase NicO PF03824.16 AAZ34379.1 - 1.6e-13 50.6 21.8 2.9e-08 33.4 6.2 2.1 1 1 1 2 2 2 2 High-affinity nickel-transport protein DsbD_2 PF13386.6 AAZ34379.1 - 0.001 19.0 19.9 0.0025 17.8 19.6 1.9 1 1 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region BIV_Env PF05858.12 AAZ34379.1 - 1.7 6.8 4.8 2.9 5.9 4.8 1.6 1 1 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) TMEM43 PF07787.12 AAZ34379.1 - 7 6.0 6.0 9.2 5.6 6.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 43 TMP-TENI PF02581.17 AAZ34380.1 - 8.9e-37 126.2 0.0 1.3e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 Thiamine monophosphate synthase NUDIX_4 PF14815.6 AAZ34380.1 - 3.6e-20 72.0 0.1 1.7e-19 69.8 0.1 2.1 3 0 0 3 3 3 1 NUDIX domain NUDIX PF00293.28 AAZ34380.1 - 5.3e-18 65.3 0.3 8.8e-18 64.6 0.3 1.4 1 0 0 1 1 1 1 NUDIX domain Aldedh PF00171.22 AAZ34381.1 - 3.9e-169 563.0 0.2 4.5e-169 562.8 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 AAZ34381.1 - 0.0016 17.6 0.0 0.0026 16.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) CoA_binding_2 PF13380.6 AAZ34381.1 - 0.12 12.8 0.2 0.39 11.2 0.0 1.9 2 0 0 2 2 2 0 CoA binding domain YCII PF03795.14 AAZ34381.1 - 0.38 11.2 2.5 4.5 7.8 0.1 3.1 3 1 0 3 3 3 0 YCII-related domain Pribosyltran PF00156.27 AAZ34382.1 - 1.4e-21 76.7 0.0 1.7e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DUF4404 PF14357.6 AAZ34383.1 - 1.6e-25 89.5 4.1 1.8e-25 89.4 4.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4404) Baculo_PEP_C PF04513.12 AAZ34383.1 - 0.0043 17.1 0.5 0.0056 16.7 0.5 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus YihI PF04220.12 AAZ34383.1 - 0.034 13.9 2.0 0.043 13.6 2.0 1.1 1 0 0 1 1 1 0 Der GTPase activator (YihI) FlxA PF14282.6 AAZ34383.1 - 0.037 14.0 2.2 0.05 13.6 2.2 1.2 1 0 0 1 1 1 0 FlxA-like protein FliT PF05400.13 AAZ34383.1 - 0.088 13.6 2.4 0.13 13.1 2.4 1.3 1 0 0 1 1 1 0 Flagellar protein FliT HBS1_N PF08938.10 AAZ34383.1 - 0.24 11.7 1.7 0.41 11.0 1.7 1.5 1 1 0 1 1 1 0 HBS1 N-terminus PIG-L PF02585.17 AAZ34384.1 - 2.1e-22 80.2 0.0 2.9e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase FliMN_C PF01052.20 AAZ34385.1 - 1.4e-11 44.2 0.3 1.9e-11 43.8 0.3 1.1 1 0 0 1 1 1 1 Type III flagellar switch regulator (C-ring) FliN C-term Polyketide_cyc2 PF10604.9 AAZ34386.1 - 6.7e-19 68.6 0.1 7.4e-19 68.4 0.1 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 AAZ34386.1 - 0.0011 19.2 0.0 0.0015 18.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Ntox46 PF15538.6 AAZ34387.1 - 5.3e-67 224.7 0.0 8.2e-67 224.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial toxin 46 Gly-zipper_OmpA PF13436.6 AAZ34387.1 - 7.2 6.5 18.8 14 5.6 18.8 1.4 1 0 0 1 1 1 0 Glycine-zipper domain MFS_1 PF07690.16 AAZ34388.1 - 5.7e-39 134.0 92.6 3.2e-34 118.4 55.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 AAZ34388.1 - 1e-06 28.3 45.6 2.8e-06 26.9 45.7 1.6 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 AAZ34388.1 - 5.5e-06 25.5 13.1 5.5e-06 25.5 13.1 2.2 1 1 1 2 2 2 1 MFS_1 like family TMEM173 PF15009.6 AAZ34388.1 - 0.044 12.9 0.3 0.078 12.1 0.3 1.4 1 0 0 1 1 1 0 Transmembrane protein 173 Peripla_BP_3 PF13377.6 AAZ34389.1 - 1e-29 104.0 0.0 5.4e-29 101.7 0.0 1.9 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 AAZ34389.1 - 2.5e-22 79.6 0.0 3.3e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 AAZ34389.1 - 2.2e-16 59.3 0.2 4.5e-16 58.4 0.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 AAZ34389.1 - 2.1e-14 53.7 0.0 3.7e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein domain HTH_31 PF13560.6 AAZ34389.1 - 3.2e-05 24.2 0.5 6.8e-05 23.1 0.5 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain TetR_N PF00440.23 AAZ34389.1 - 0.0001 22.0 0.4 0.00044 20.0 0.1 2.1 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_Tnp_ISL3 PF13542.6 AAZ34389.1 - 0.0083 15.5 0.1 0.017 14.5 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_3 PF01381.22 AAZ34389.1 - 0.029 14.4 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix DNA_pol_lambd_f PF10391.9 AAZ34389.1 - 0.071 12.9 0.2 0.22 11.4 0.1 1.8 1 1 1 2 2 2 0 Fingers domain of DNA polymerase lambda HTH_7 PF02796.15 AAZ34389.1 - 0.095 12.8 0.3 0.24 11.5 0.3 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Aconitase PF00330.20 AAZ34391.1 - 6e-186 618.9 0.0 8.1e-186 618.5 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 AAZ34391.1 - 3e-47 160.2 0.0 5.2e-47 159.5 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain MinC_C PF03775.16 AAZ34392.1 - 7.9e-31 106.1 0.0 1.2e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Septum formation inhibitor MinC, C-terminal domain MinC_N PF05209.13 AAZ34392.1 - 2.8e-23 81.8 0.0 4.3e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 Septum formation inhibitor MinC, N-terminal domain Transposase_mut PF00872.18 AAZ34393.1 - 1.5e-117 392.7 0.0 1.9e-117 392.3 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ34393.1 - 7.7e-05 23.0 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain DUF4844 PF16133.5 AAZ34393.1 - 0.23 12.0 0.0 0.55 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) Ppnp PF06865.11 AAZ34394.1 - 5.4e-37 126.1 0.3 5.9e-37 126.0 0.3 1.0 1 0 0 1 1 1 1 Pyrimidine/purine nucleoside phosphorylase Cupin_3 PF05899.12 AAZ34394.1 - 0.0018 17.9 0.0 0.0023 17.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) CENP-C_C PF11699.8 AAZ34394.1 - 0.026 14.7 0.0 0.044 14.0 0.0 1.4 1 1 0 1 1 1 0 Mif2/CENP-C like Cupin_2 PF07883.11 AAZ34394.1 - 0.15 11.8 0.0 0.24 11.2 0.0 1.3 1 1 0 1 1 1 0 Cupin domain DUF4791 PF16039.5 AAZ34395.1 - 0.00051 19.6 0.7 0.00094 18.7 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4791) DUF420 PF04238.12 AAZ34395.1 - 0.032 14.5 1.4 0.032 14.5 1.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF420) DUF5013 PF16405.5 AAZ34395.1 - 0.15 12.4 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5013) CBP_BcsG PF11658.8 AAZ34395.1 - 0.15 10.4 1.9 0.23 9.8 1.9 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG DUF4131 PF13567.6 AAZ34395.1 - 0.48 10.1 12.6 5.5 6.6 0.7 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) SLATT_5 PF18160.1 AAZ34395.1 - 0.6 9.4 4.5 1.4 8.2 4.5 1.6 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF1772 PF08592.11 AAZ34395.1 - 2.3 8.5 16.5 1.3 9.4 2.5 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) SPC25 PF06703.11 AAZ34395.1 - 8.5 6.1 7.8 6.7 6.5 2.1 3.0 2 2 0 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Sdh_cyt PF01127.22 AAZ34396.1 - 2e-08 34.3 16.2 8.2e-08 32.3 8.7 2.0 1 1 1 2 2 2 2 Succinate dehydrogenase/Fumarate reductase transmembrane subunit CybS PF05328.12 AAZ34396.1 - 0.098 12.3 1.7 0.31 10.7 1.7 1.8 1 1 0 1 1 1 0 CybS, succinate dehydrogenase cytochrome B small subunit DUF945 PF06097.11 AAZ34397.1 - 3.9e-105 352.6 17.1 4.4e-105 352.5 17.1 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF945) DsbB PF02600.16 AAZ34398.1 - 2.2e-25 89.8 14.1 2.9e-25 89.4 14.1 1.1 1 0 0 1 1 1 1 Disulfide bond formation protein DsbB T2SSM PF04612.12 AAZ34398.1 - 0.062 13.3 0.7 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M ABC_tran PF00005.27 AAZ34399.1 - 2.9e-21 76.4 0.0 4.3e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter OB_MalK PF17912.1 AAZ34399.1 - 1.5e-08 35.3 0.0 9.8e-08 32.7 0.0 2.4 2 0 0 2 2 2 1 MalK OB fold domain AAA_29 PF13555.6 AAZ34399.1 - 3.5e-05 23.5 0.0 7.6e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain TOBE_2 PF08402.10 AAZ34399.1 - 6.3e-05 23.1 0.0 0.00011 22.3 0.0 1.4 1 0 0 1 1 1 1 TOBE domain RsgA_GTPase PF03193.16 AAZ34399.1 - 0.00041 20.3 0.0 0.0013 18.7 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 AAZ34399.1 - 0.0014 18.5 0.1 0.0093 15.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system Adeno_IVa2 PF02456.15 AAZ34399.1 - 0.0045 15.8 0.0 0.0072 15.2 0.0 1.2 1 0 0 1 1 1 1 Adenovirus IVa2 protein AAA_16 PF13191.6 AAZ34399.1 - 0.0074 16.7 0.0 0.01 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 AAZ34399.1 - 0.013 15.4 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain G-alpha PF00503.20 AAZ34399.1 - 0.026 13.7 0.0 0.035 13.3 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit AAA_18 PF13238.6 AAZ34399.1 - 0.039 14.5 0.1 0.35 11.4 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AAZ34399.1 - 0.057 13.7 0.0 0.29 11.4 0.0 2.1 2 1 0 2 2 2 0 AAA domain CysA_C_terminal PF17850.1 AAZ34399.1 - 0.064 13.8 0.0 0.16 12.5 0.0 1.8 1 0 0 1 1 1 0 CysA C-terminal regulatory domain AAA_23 PF13476.6 AAZ34399.1 - 0.073 13.6 1.6 0.13 12.7 0.3 1.8 1 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 AAZ34399.1 - 0.076 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 AAZ34399.1 - 0.079 12.9 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 AAZ34399.1 - 0.079 13.0 0.2 0.22 11.6 0.2 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.6 AAZ34399.1 - 0.099 12.2 0.0 0.27 10.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 AAZ34399.1 - 0.17 11.9 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase PF06745.13 AAZ34400.1 - 3.4e-18 65.8 0.0 5.4e-11 42.3 0.0 2.1 1 1 1 2 2 2 2 KaiC AAA_25 PF13481.6 AAZ34400.1 - 3.2e-14 53.0 0.0 9.7e-14 51.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain Rubredoxin_2 PF18073.1 AAZ34400.1 - 6.7e-11 41.7 6.3 1e-10 41.1 6.3 1.3 1 0 0 1 1 1 1 Rubredoxin metal binding domain ChlI PF13541.6 AAZ34400.1 - 2.8e-08 33.6 0.0 8.1e-08 32.1 0.0 1.8 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase Lon_C PF05362.13 AAZ34400.1 - 8e-07 28.8 0.0 1.8e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain DnaB_C PF03796.15 AAZ34400.1 - 6.2e-06 25.7 0.0 9.8e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 AAZ34400.1 - 2.8e-05 24.6 0.1 0.0014 19.0 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain RecA PF00154.21 AAZ34400.1 - 6.7e-05 22.5 0.3 0.0001 21.9 0.3 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Rad51 PF08423.11 AAZ34400.1 - 6.8e-05 22.3 0.4 0.00061 19.1 0.1 2.1 1 1 0 2 2 2 1 Rad51 AAA PF00004.29 AAZ34400.1 - 0.00055 20.4 0.0 0.001 19.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AAZ34400.1 - 0.00075 19.8 0.1 0.0018 18.5 0.1 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 AAZ34400.1 - 0.0041 16.4 0.0 0.0065 15.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) GvpD PF07088.11 AAZ34400.1 - 0.0059 15.3 0.1 0.096 11.3 0.0 2.3 1 1 2 3 3 3 1 GvpD gas vesicle protein AAA_24 PF13479.6 AAZ34400.1 - 0.0068 16.2 0.0 0.023 14.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 AAZ34400.1 - 0.015 15.3 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain MCM PF00493.23 AAZ34400.1 - 0.03 13.4 0.0 0.052 12.6 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain ABC_tran PF00005.27 AAZ34400.1 - 0.065 13.7 0.1 0.38 11.3 0.1 1.9 1 1 1 2 2 2 0 ABC transporter NTPase_1 PF03266.15 AAZ34400.1 - 0.071 13.0 0.3 0.32 10.9 0.3 2.0 1 1 0 1 1 1 0 NTPase AAA_29 PF13555.6 AAZ34400.1 - 0.17 11.7 0.4 0.48 10.2 0.1 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain NACHT PF05729.12 AAZ34400.1 - 0.18 11.7 0.1 0.44 10.4 0.1 1.8 1 1 0 1 1 1 0 NACHT domain PAXNEB PF05625.11 AAZ34400.1 - 0.25 10.5 0.4 0.42 9.7 0.4 1.3 1 0 0 1 1 1 0 PAXNEB protein zf-C2H2_6 PF13912.6 AAZ34400.1 - 0.32 11.1 2.4 0.7 10.0 0.1 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger MarR_2 PF12802.7 AAZ34402.1 - 8.2e-09 35.2 0.0 1.3e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 AAZ34402.1 - 3.6e-07 30.6 0.0 5.3e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR PF01047.22 AAZ34402.1 - 5e-06 26.3 0.0 8.3e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 AAZ34402.1 - 0.0008 18.9 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 AAZ34402.1 - 0.022 14.6 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 AAZ34402.1 - 0.051 13.6 0.1 0.12 12.5 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain Dpoe2NT PF12213.8 AAZ34402.1 - 0.083 13.2 0.1 0.22 11.8 0.0 1.6 2 0 0 2 2 2 0 DNA polymerases epsilon N terminal TrmB PF01978.19 AAZ34402.1 - 0.15 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_WhiA PF02650.14 AAZ34402.1 - 0.16 12.4 0.0 0.26 11.7 0.0 1.3 1 0 0 1 1 1 0 WhiA C-terminal HTH domain LolA PF03548.15 AAZ34403.1 - 2.1e-06 27.6 0.0 3.7e-06 26.7 0.0 1.4 1 1 0 1 1 1 1 Outer membrane lipoprotein carrier protein LolA TniQ PF06527.11 AAZ34404.1 - 1.7e-07 32.0 0.1 8.4e-07 29.8 0.1 2.2 1 1 0 1 1 1 1 TniQ TnsD PF15978.5 AAZ34404.1 - 0.0072 15.4 0.1 0.013 14.5 0.1 1.5 2 0 0 2 2 2 1 Tn7-like transposition protein D OpuAC PF04069.12 AAZ34405.1 - 3.4e-62 210.3 0.0 4e-62 210.1 0.0 1.1 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system TPR_14 PF13428.6 AAZ34406.1 - 1.6e-13 50.2 8.2 0.00037 21.1 0.0 3.1 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 AAZ34406.1 - 2.7e-11 42.7 1.1 0.0025 17.8 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 AAZ34406.1 - 1.2e-10 41.8 4.2 5.2e-08 33.3 1.7 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 AAZ34406.1 - 4.2e-09 36.9 8.3 3.7e-07 30.7 5.8 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 AAZ34406.1 - 4.3e-09 35.9 0.0 0.012 15.8 0.1 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 AAZ34406.1 - 1.4e-08 34.9 4.7 0.00018 21.8 2.7 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 AAZ34406.1 - 1.6e-08 34.7 2.4 0.18 12.5 0.0 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 AAZ34406.1 - 3.4e-07 29.8 0.0 0.022 14.5 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 AAZ34406.1 - 2.2e-06 27.1 1.1 1.4e-05 24.5 1.1 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 AAZ34406.1 - 5.9e-06 25.9 1.8 0.72 10.0 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 AAZ34406.1 - 9.4e-06 25.7 0.1 0.21 12.0 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 AAZ34406.1 - 0.00014 22.0 0.1 0.00098 19.3 0.1 1.9 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 AAZ34406.1 - 0.0022 18.1 8.4 0.014 15.6 4.9 2.1 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 AAZ34406.1 - 0.0029 17.3 0.0 2.2 8.1 0.0 2.3 2 1 0 2 2 2 2 TPR repeat TPR_10 PF13374.6 AAZ34406.1 - 0.0031 17.3 5.3 1.1 9.2 1.9 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 AAZ34406.1 - 0.017 15.7 16.4 0.03 14.9 1.9 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat NARP1 PF12569.8 AAZ34406.1 - 0.037 12.9 0.0 0.11 11.4 0.0 1.6 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 ABC_tran PF00005.27 AAZ34407.1 - 9.1e-34 116.9 0.0 1.8e-33 115.9 0.0 1.5 2 0 0 2 2 2 1 ABC transporter BCA_ABC_TP_C PF12399.8 AAZ34407.1 - 6.2e-05 22.8 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter SMC_N PF02463.19 AAZ34407.1 - 9.2e-05 22.0 0.0 0.00032 20.2 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AAZ34407.1 - 0.0004 20.3 0.3 0.15 11.8 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AAZ34407.1 - 0.012 16.1 0.2 0.03 14.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 AAZ34407.1 - 0.061 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 AAZ34407.1 - 0.065 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 AAZ34407.1 - 0.089 13.0 0.0 0.41 10.9 0.0 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 AAZ34407.1 - 0.12 12.2 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain HTH_18 PF12833.7 AAZ34408.1 - 6.5e-21 74.4 0.3 1.4e-20 73.3 0.3 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain DJ-1_PfpI PF01965.24 AAZ34408.1 - 2.9e-18 66.2 0.0 4e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family HTH_AraC PF00165.23 AAZ34408.1 - 2.3e-16 59.4 0.1 6.1e-09 35.8 0.0 2.3 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Fer2_2 PF01799.20 AAZ34408.1 - 0.075 13.1 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 [2Fe-2S] binding domain GATase_3 PF07685.14 AAZ34408.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain DUF4568 PF15132.6 AAZ34409.1 - 0.062 12.7 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4568) Tox-SHH PF15652.6 AAZ34410.1 - 1.4e-26 93.3 0.0 2.4e-26 92.6 0.0 1.4 1 0 0 1 1 1 1 HNH/Endo VII superfamily toxin with a SHH signature RHS PF03527.14 AAZ34410.1 - 3.4e-20 71.5 0.2 1e-19 70.0 0.2 1.8 1 0 0 1 1 1 1 RHS protein DUF4585 PF15232.6 AAZ34410.1 - 0.11 12.5 0.7 0.3 11.2 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4585) DLH PF01738.18 AAZ34411.1 - 6.7e-44 150.0 0.0 7.9e-44 149.8 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 AAZ34411.1 - 1.6e-06 28.1 0.0 2.3e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 AAZ34411.1 - 5.3e-06 26.1 0.1 0.0028 17.2 0.0 2.5 1 1 1 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 AAZ34411.1 - 2.6e-05 23.6 0.1 0.0015 17.9 0.0 2.4 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AAZ34411.1 - 0.0024 17.6 0.0 0.9 9.1 0.0 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold BAAT_C PF08840.11 AAZ34411.1 - 0.0044 17.0 0.2 2 8.3 0.0 2.2 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 AAZ34411.1 - 0.012 15.4 0.1 0.036 13.9 0.1 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold Methyltransf_20 PF12147.8 AAZ34411.1 - 0.021 14.0 0.0 0.028 13.6 0.0 1.1 1 0 0 1 1 1 0 Putative methyltransferase RbsD_FucU PF05025.13 AAZ34412.1 - 9.4e-44 149.1 0.0 1e-43 148.9 0.0 1.0 1 0 0 1 1 1 1 RbsD / FucU transport protein family GST_N_3 PF13417.6 AAZ34413.1 - 6.7e-14 52.1 0.0 1.2e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 AAZ34413.1 - 4.6e-12 46.1 0.0 7.2e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AAZ34413.1 - 2.4e-08 34.2 0.0 4e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 AAZ34413.1 - 5.1e-07 29.8 0.0 8.4e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 AAZ34413.1 - 1.9e-05 24.6 0.7 0.00013 22.0 0.2 2.7 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 AAZ34413.1 - 0.017 15.3 0.0 0.026 14.7 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Deltaretro_Tax PF05599.11 AAZ34413.1 - 0.11 13.0 0.0 0.18 12.3 0.0 1.3 1 0 0 1 1 1 0 Deltaretrovirus Tax protein HTH_18 PF12833.7 AAZ34414.1 - 1.9e-21 76.1 0.4 3.3e-21 75.3 0.4 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAZ34414.1 - 3.1e-10 39.9 0.0 0.00033 20.7 0.0 2.3 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family AraC_binding PF02311.19 AAZ34414.1 - 4.4e-07 29.9 0.2 1.1e-06 28.5 0.1 1.7 1 1 1 2 2 2 1 AraC-like ligand binding domain Cupin_2 PF07883.11 AAZ34414.1 - 0.0015 18.2 0.1 0.0031 17.2 0.1 1.5 1 0 0 1 1 1 1 Cupin domain HTH_23 PF13384.6 AAZ34414.1 - 0.096 12.5 0.0 0.7 9.8 0.0 2.2 2 0 0 2 2 2 0 Homeodomain-like domain PuR_N PF09182.10 AAZ34414.1 - 0.2 11.6 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal ACP_syn_III_C PF08541.10 AAZ34415.1 - 2.5e-06 27.5 0.9 3.6e-05 23.8 0.0 2.6 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 AAZ34415.1 - 6.7e-06 25.9 0.3 1.9e-05 24.4 0.3 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III HTH_20 PF12840.7 AAZ34416.1 - 1.1e-07 31.8 2.8 4.6e-07 29.8 0.4 2.6 2 1 0 2 2 2 1 Helix-turn-helix domain HemN_C PF06969.16 AAZ34416.1 - 0.014 15.4 0.1 0.68 10.0 0.0 2.5 2 0 0 2 2 2 0 HemN C-terminal domain DprA_WH PF17782.1 AAZ34416.1 - 0.015 15.4 0.5 0.052 13.7 0.5 1.9 1 0 0 1 1 1 0 DprA winged helix domain PaaX PF07848.12 AAZ34416.1 - 0.017 15.3 0.2 0.16 12.2 0.1 2.3 2 0 0 2 2 2 0 PaaX-like protein HTH_IclR PF09339.10 AAZ34416.1 - 0.029 14.2 2.7 0.12 12.1 0.2 2.9 3 0 0 3 3 3 0 IclR helix-turn-helix domain DUF4423 PF14394.6 AAZ34416.1 - 0.039 13.7 0.0 4.6 6.9 0.0 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4423) HTH_27 PF13463.6 AAZ34416.1 - 0.053 14.0 0.0 17 6.0 0.0 2.6 2 0 0 2 2 2 0 Winged helix DNA-binding domain GPP34 PF05719.11 AAZ34416.1 - 0.054 13.5 0.9 3.1 7.8 0.1 2.2 1 1 1 2 2 2 0 Golgi phosphoprotein 3 (GPP34) TrmB PF01978.19 AAZ34416.1 - 0.066 13.1 0.0 5.5 7.0 0.0 2.5 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB DUF1627 PF07789.12 AAZ34416.1 - 0.068 12.8 0.0 0.097 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1627) HTH_5 PF01022.20 AAZ34416.1 - 0.1 12.5 0.0 0.35 10.8 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family AbiEi_4 PF13338.6 AAZ34416.1 - 0.15 12.2 3.1 1.7 8.9 0.2 3.0 3 0 0 3 3 3 0 Transcriptional regulator, AbiEi antitoxin BPD_transp_1 PF00528.22 AAZ34417.1 - 5.9e-30 104.4 12.7 5.9e-30 104.4 12.7 1.8 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Pex2_Pex12 PF04757.14 AAZ34417.1 - 0.094 12.3 0.2 0.19 11.3 0.2 1.6 1 1 0 1 1 1 0 Pex2 / Pex12 amino terminal region DUF4148 PF13663.6 AAZ34417.1 - 0.23 11.7 3.4 0.47 10.7 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) Hydrolase_4 PF12146.8 AAZ34418.1 - 7.3e-13 48.3 0.0 8.5e-12 44.8 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AAZ34418.1 - 1.1e-07 32.7 1.4 1.4e-07 32.3 1.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AAZ34418.1 - 0.0014 18.4 0.0 0.047 13.3 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold DUF1100 PF06500.11 AAZ34418.1 - 0.0068 15.2 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_8 PF06259.12 AAZ34418.1 - 0.015 14.9 0.1 0.026 14.2 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Peptidase_S15 PF02129.18 AAZ34418.1 - 0.048 13.3 0.0 0.65 9.5 0.0 2.0 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) PdxA PF04166.12 AAZ34419.1 - 1e-106 356.5 0.0 1.2e-106 356.3 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthetic protein PdxA Methyltransf_23 PF13489.6 AAZ34420.1 - 1.5e-17 63.9 0.0 2.2e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAZ34420.1 - 1.4e-15 57.7 0.1 2.4e-15 57.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAZ34420.1 - 1.1e-14 54.9 0.1 2e-14 54.1 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAZ34420.1 - 9.3e-14 51.5 0.0 1.7e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAZ34420.1 - 1.5e-12 48.1 0.0 3.7e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain HTH_20 PF12840.7 AAZ34420.1 - 3.7e-12 46.1 0.1 2.3e-11 43.6 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_5 PF01022.20 AAZ34420.1 - 1.7e-06 27.8 0.0 6.7e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family Ubie_methyltran PF01209.18 AAZ34420.1 - 1.6e-05 24.4 0.0 2.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 AAZ34420.1 - 0.0039 16.5 0.0 0.0057 16.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain MarR_2 PF12802.7 AAZ34420.1 - 0.083 12.8 0.1 0.29 11.0 0.1 2.0 1 0 0 1 1 1 0 MarR family RrnaAD PF00398.20 AAZ34420.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PCMT PF01135.19 AAZ34420.1 - 0.12 12.1 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Peptidase_M48 PF01435.18 AAZ34421.1 - 3.6e-35 121.5 0.0 4.8e-35 121.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Ribosomal_L17 PF01196.19 AAZ34421.1 - 0.079 13.9 0.1 0.14 13.0 0.0 1.6 1 1 0 1 1 1 0 Ribosomal protein L17 DUF1403 PF07183.11 AAZ34421.1 - 0.1 12.2 1.9 0.23 11.0 0.2 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1403) LPAM_1 PF08139.12 AAZ34421.1 - 0.29 11.7 2.2 0.65 10.6 2.2 1.6 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Peptidase_M13 PF01431.21 AAZ34421.1 - 0.69 9.5 2.9 2.8 7.5 0.9 2.7 2 1 1 3 3 3 0 Peptidase family M13 Hydrolase_4 PF12146.8 AAZ34423.1 - 6.5e-06 25.6 0.2 0.042 13.1 0.1 2.4 1 1 1 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 AAZ34423.1 - 8.2e-05 22.3 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 AAZ34423.1 - 0.0004 21.1 3.4 0.0012 19.5 2.5 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 AAZ34423.1 - 0.013 15.2 0.0 0.096 12.4 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF2048 PF09752.9 AAZ34423.1 - 0.023 13.8 0.0 0.037 13.1 0.0 1.4 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Abhydrolase_1 PF00561.20 AAZ34423.1 - 0.029 14.0 0.0 0.17 11.5 0.0 1.9 1 1 1 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 AAZ34423.1 - 0.074 12.9 0.1 0.57 10.0 0.1 2.2 2 1 1 3 3 3 0 alpha/beta hydrolase fold MurJ PF03023.14 AAZ34424.1 - 2.6e-40 138.4 14.9 3.2e-40 138.1 14.9 1.1 1 0 0 1 1 1 1 Lipid II flippase MurJ Polysacc_synt_C PF14667.6 AAZ34424.1 - 2.1e-07 31.1 15.0 2.1e-07 31.1 15.0 4.5 3 2 0 4 4 4 1 Polysaccharide biosynthesis C-terminal domain Polysacc_synt_3 PF13440.6 AAZ34424.1 - 0.00084 18.6 0.1 0.0018 17.6 0.1 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein MatE PF01554.18 AAZ34424.1 - 9.5 5.8 21.9 0.23 11.1 4.3 4.0 4 1 0 4 4 4 0 MatE GATase_5 PF13507.6 AAZ34425.1 - 8.6e-105 349.5 0.3 1.2e-104 349.0 0.3 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 AAZ34425.1 - 3.8e-44 150.6 0.1 1.5e-28 99.9 0.0 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 AAZ34425.1 - 1.8e-41 140.7 0.0 3e-41 140.0 0.0 1.4 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 AAZ34425.1 - 4.7e-23 81.5 0.0 9.7e-23 80.5 0.0 1.6 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain AIRS PF00586.24 AAZ34425.1 - 0.035 14.8 0.1 1.4 9.6 0.0 2.9 2 0 0 2 2 2 0 AIR synthase related protein, N-terminal domain MlaA PF04333.13 AAZ34426.1 - 7.5e-66 221.6 0.1 9.9e-66 221.2 0.1 1.2 1 0 0 1 1 1 1 MlaA lipoprotein Terminase_6C PF17289.2 AAZ34427.1 - 0.011 15.8 0.0 0.022 14.9 0.0 1.4 1 1 0 1 1 1 0 Terminase RNaseH-like domain HTH_Tnp_1 PF01527.20 AAZ34428.1 - 5.6e-18 65.0 1.4 7.9e-18 64.6 1.4 1.2 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.6 AAZ34428.1 - 0.00015 21.7 0.2 0.00031 20.7 0.0 1.6 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 AAZ34428.1 - 0.0003 20.8 0.1 0.00058 19.9 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AAZ34428.1 - 0.00035 20.3 1.4 0.0011 18.7 0.1 2.2 2 1 0 2 2 2 1 Homeodomain-like domain KASH_CCD PF14662.6 AAZ34428.1 - 0.006 16.4 3.0 0.0068 16.3 3.0 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH TSC22 PF01166.18 AAZ34428.1 - 0.0078 16.5 2.3 0.01 16.1 1.0 1.7 2 0 0 2 2 2 1 TSC-22/dip/bun family FlxA PF14282.6 AAZ34428.1 - 0.019 14.9 1.6 0.029 14.4 1.6 1.3 1 0 0 1 1 1 0 FlxA-like protein DivIC PF04977.15 AAZ34428.1 - 0.036 13.8 4.3 0.062 13.1 4.3 1.4 1 1 0 1 1 1 0 Septum formation initiator Shugoshin_N PF07558.11 AAZ34428.1 - 0.041 13.8 0.6 0.072 13.0 0.6 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region BLOC1_2 PF10046.9 AAZ34428.1 - 0.045 14.1 0.4 0.066 13.5 0.4 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3287 PF11690.8 AAZ34428.1 - 0.046 13.4 2.1 0.24 11.1 0.6 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF3287) M PF02370.16 AAZ34428.1 - 0.057 14.0 0.8 0.23 12.1 0.3 2.2 1 1 1 2 2 2 0 M protein repeat DUF4140 PF13600.6 AAZ34428.1 - 0.097 13.1 3.3 0.21 12.0 3.3 1.7 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) ZapB PF06005.12 AAZ34428.1 - 0.42 11.1 7.6 3.5 8.1 4.2 2.2 1 1 2 3 3 3 0 Cell division protein ZapB ABC_tran_CTD PF16326.5 AAZ34428.1 - 0.54 10.5 7.5 0.12 12.6 4.3 1.7 2 0 0 2 2 2 0 ABC transporter C-terminal domain BPD_transp_1 PF00528.22 AAZ34429.1 - 1.3e-16 60.9 13.1 1.7e-16 60.5 13.1 1.2 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component Phage_holin_2_2 PF10746.9 AAZ34429.1 - 0.047 13.4 0.9 1.1 9.0 0.1 2.5 2 0 0 2 2 2 0 Phage holin T7 family, holin superfamily II Nuc_deoxyrib_tr PF05014.15 AAZ34430.1 - 2.5e-42 144.0 0.0 3e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase Nuc_deoxyri_tr2 PF15891.5 AAZ34430.1 - 0.072 13.4 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase like Tma16 PF11176.8 AAZ34430.1 - 0.23 11.4 0.0 0.36 10.7 0.0 1.2 1 0 0 1 1 1 0 Translation machinery-associated protein 16 SLT PF01464.20 AAZ34431.1 - 0.17 11.6 0.0 1.4 8.6 0.0 2.0 1 1 0 1 1 1 0 Transglycosylase SLT domain Metallophos PF00149.28 AAZ34432.1 - 6.4e-20 72.5 0.4 9.2e-20 72.0 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AAZ34432.1 - 4.1e-11 43.3 0.1 1.8e-10 41.3 0.1 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 AAZ34432.1 - 0.063 12.6 0.1 0.77 9.0 0.0 2.3 1 1 1 2 2 2 0 Metallophosphoesterase, calcineurin superfamily Lyase_1 PF00206.20 AAZ34433.1 - 2.3e-106 355.7 0.0 2.8e-106 355.4 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 AAZ34433.1 - 1.6e-25 89.3 0.1 3.4e-25 88.2 0.1 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus GATase_2 PF00310.21 AAZ34434.1 - 9.4e-171 568.2 0.0 1.2e-170 567.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 AAZ34434.1 - 4.4e-148 493.3 0.0 9.2e-148 492.3 0.0 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 AAZ34434.1 - 2.5e-103 345.4 0.0 3.7e-103 344.8 0.0 1.2 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.19 AAZ34434.1 - 5.5e-77 257.7 6.5 9.5e-77 256.9 6.5 1.4 1 0 0 1 1 1 1 GXGXG motif FMN_dh PF01070.18 AAZ34434.1 - 2.8e-05 23.3 0.1 6.4e-05 22.1 0.1 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase PAAR_motif PF05488.13 AAZ34435.1 - 1.1e-17 63.9 0.5 3.4e-17 62.4 0.5 1.8 1 0 0 1 1 1 1 PAAR motif Helicase_C_2 PF13307.6 AAZ34436.1 - 8.9e-35 120.4 0.0 2.8e-34 118.8 0.0 1.8 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 AAZ34436.1 - 3e-14 53.0 0.0 4.7e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 DEAD_2 DEAD PF00270.29 AAZ34436.1 - 6e-07 29.4 0.0 0.00043 20.1 0.0 3.1 3 0 0 3 3 3 2 DEAD/DEAH box helicase HBB PF06777.11 AAZ34436.1 - 0.006 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Helical and beta-bridge domain SNF2_N PF00176.23 AAZ34436.1 - 0.013 14.3 0.0 0.073 11.8 0.0 1.9 1 1 0 1 1 1 0 SNF2 family N-terminal domain Allantoicase PF03561.15 AAZ34438.1 - 4.2e-95 315.4 0.0 1.6e-47 161.1 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat Phage_integrase PF00589.22 AAZ34439.1 - 1.1e-11 44.8 0.5 4.8e-11 42.8 0.3 1.9 2 0 0 2 2 2 1 Phage integrase family Sigma54_activat PF00158.26 AAZ34440.1 - 4.2e-66 221.8 0.0 6.7e-66 221.1 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Response_reg PF00072.24 AAZ34440.1 - 1.2e-28 99.5 0.0 2.6e-28 98.4 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Sigma54_activ_2 PF14532.6 AAZ34440.1 - 2e-26 92.8 0.0 7.7e-26 90.8 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 AAZ34440.1 - 5.9e-15 54.8 2.9 5.9e-15 54.8 2.9 2.0 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family HTH_50 PF18024.1 AAZ34440.1 - 0.00027 20.5 0.2 0.00082 18.9 0.2 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain Mg_chelatase PF01078.21 AAZ34440.1 - 0.00067 19.1 0.0 0.013 14.9 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 AAZ34440.1 - 0.0034 17.4 0.0 0.0071 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) HTH_30 PF13556.6 AAZ34440.1 - 0.0042 16.8 0.3 0.0042 16.8 0.3 2.5 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain HTH_20 PF12840.7 AAZ34440.1 - 0.014 15.4 1.1 1.3 9.2 0.3 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain AAA_22 PF13401.6 AAZ34440.1 - 0.019 15.2 0.0 1.1 9.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 AAZ34440.1 - 0.07 13.6 0.0 0.14 12.5 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Hexapep PF00132.24 AAZ34441.1 - 1.2e-24 85.0 26.1 5.1e-07 29.2 0.2 5.7 4 1 1 5 5 5 5 Bacterial transferase hexapeptide (six repeats) LpxD PF04613.14 AAZ34441.1 - 1.3e-20 72.9 0.2 2.4e-20 72.1 0.2 1.4 1 0 0 1 1 1 1 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD Hexapep_2 PF14602.6 AAZ34441.1 - 5.6e-06 26.0 25.9 0.003 17.3 3.2 5.8 4 1 1 5 5 5 4 Hexapeptide repeat of succinyl-transferase HSBP1 PF06825.12 AAZ34441.1 - 0.021 14.7 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 Heat shock factor binding protein 1 HBM PF16591.5 AAZ34442.1 - 7.6e-68 228.7 26.3 7.6e-68 228.7 26.3 3.5 3 1 0 3 3 3 1 Helical bimodular sensor domain MCPsignal PF00015.21 AAZ34442.1 - 2.6e-44 151.1 25.8 2.6e-44 151.1 25.8 4.5 2 2 3 5 5 5 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AAZ34442.1 - 1.8e-12 47.4 11.9 8.2e-09 35.7 1.2 4.7 4 1 0 4 4 4 2 HAMP domain Elf4 PF07011.11 AAZ34442.1 - 0.067 13.1 5.4 0.084 12.8 0.1 3.3 2 1 1 3 3 3 0 Early Flowering 4 domain PEX11 PF05648.14 AAZ34442.1 - 2.4 7.6 15.5 0.54 9.7 0.3 4.1 3 1 0 4 4 4 0 Peroxisomal biogenesis factor 11 (PEX11) DUF4440 PF14534.6 AAZ34443.1 - 1.5e-17 63.9 0.0 1.8e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 AAZ34443.1 - 2.6e-06 28.0 0.0 3.2e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.6 AAZ34443.1 - 0.00023 21.4 0.1 0.00032 21.0 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.6 AAZ34443.1 - 0.0011 19.1 0.1 0.0013 18.9 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain CaMKII_AD PF08332.10 AAZ34443.1 - 0.0019 18.3 0.4 0.0035 17.5 0.4 1.4 1 1 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain SnoaL PF07366.12 AAZ34443.1 - 0.0035 17.2 0.0 0.0047 16.7 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase DUF4972 PF16342.5 AAZ34443.1 - 0.03 14.0 0.1 0.05 13.3 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4972) DUF3600 PF12207.8 AAZ34443.1 - 0.076 12.9 0.1 0.1 12.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3600) EAL PF00563.20 AAZ34444.1 - 7.7e-42 143.4 0.2 1.3e-41 142.7 0.2 1.3 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AAZ34444.1 - 1.2e-37 129.1 0.0 3e-37 127.9 0.0 1.6 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Holin_BlyA PF05102.12 AAZ34444.1 - 0.044 13.8 0.1 0.11 12.5 0.1 1.7 1 0 0 1 1 1 0 holin, BlyA family CheW PF01584.19 AAZ34445.1 - 5.6e-39 132.9 1.5 6.3e-39 132.8 1.5 1.0 1 0 0 1 1 1 1 CheW-like domain Biotin_lipoyl PF00364.22 AAZ34445.1 - 0.18 11.7 2.0 11 5.9 0.1 2.3 1 1 1 2 2 2 0 Biotin-requiring enzyme HAD_2 PF13419.6 AAZ34446.1 - 1.6e-20 73.9 0.0 1.9e-20 73.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAZ34446.1 - 6.5e-10 39.7 0.0 7.9e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AAZ34446.1 - 2.5e-08 33.8 0.0 3.8e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 AAZ34446.1 - 0.00029 21.3 0.0 0.00038 20.9 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AAZ34446.1 - 0.055 13.6 0.0 0.076 13.1 0.0 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Ribosomal_S13 PF00416.22 AAZ34447.1 - 0.02 15.3 0.5 0.037 14.4 0.5 1.4 1 0 0 1 1 1 0 Ribosomal protein S13/S18 Herpes_UL25 PF01499.16 AAZ34447.1 - 0.29 9.6 8.5 0.37 9.2 8.5 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF3584 PF12128.8 AAZ34447.1 - 0.34 8.4 13.4 0.44 8.0 13.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) NBD_C PF17042.5 AAZ34447.1 - 0.42 11.1 8.1 0.64 10.5 8.1 1.4 1 0 0 1 1 1 0 Nucleotide-binding C-terminal domain MafB PF06255.13 AAZ34447.1 - 0.88 8.9 5.7 2.1 7.7 2.6 2.0 1 1 1 2 2 2 0 Neisseria toxin MafB FUSC PF04632.12 AAZ34447.1 - 0.89 8.0 12.2 1.1 7.7 12.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Casc1_N PF15927.5 AAZ34447.1 - 1.4 8.6 13.8 2 8.0 13.8 1.3 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Atg14 PF10186.9 AAZ34447.1 - 1.9 7.5 5.9 2.7 7.0 5.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MgtE PF01769.16 AAZ34448.1 - 1.4e-25 90.1 9.4 1.4e-25 90.1 9.4 1.6 2 0 0 2 2 2 1 Divalent cation transporter MgtE_N PF03448.17 AAZ34448.1 - 1.4e-24 86.7 10.0 1.4e-24 86.7 10.0 2.8 3 0 0 3 3 3 1 MgtE intracellular N domain CBS PF00571.28 AAZ34448.1 - 7.1e-15 55.2 2.5 8.1e-08 32.6 0.1 2.9 2 0 0 2 2 2 2 CBS domain 5_3_exonuc PF01367.20 AAZ34448.1 - 0.15 12.7 1.3 3.5 8.3 0.1 2.6 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Alpha-amylase PF00128.24 AAZ34449.1 - 2.3e-20 73.4 0.0 9.5e-13 48.4 0.0 2.9 1 1 1 2 2 2 2 Alpha amylase, catalytic domain DUF3459 PF11941.8 AAZ34449.1 - 1.6e-18 66.8 0.0 5.6e-18 65.0 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3459) CBM_48 PF02922.18 AAZ34449.1 - 0.0006 20.1 0.0 0.0012 19.2 0.0 1.5 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) FecCD PF01032.18 AAZ34450.1 - 2e-82 276.7 37.0 2.4e-82 276.4 37.0 1.0 1 0 0 1 1 1 1 FecCD transport family ABC-3 PF00950.17 AAZ34450.1 - 3.2e-06 26.8 10.1 3.2e-06 26.8 10.1 2.1 1 1 1 2 2 2 1 ABC 3 transport family MCPsignal PF00015.21 AAZ34451.1 - 9.7e-44 149.2 39.6 3.4e-43 147.4 24.8 3.8 1 1 1 3 3 3 3 Methyl-accepting chemotaxis protein (MCP) signalling domain 4HB_MCP_1 PF12729.7 AAZ34451.1 - 4.8e-21 75.1 0.1 4.8e-21 75.1 0.1 4.0 3 2 1 4 4 4 1 Four helix bundle sensory module for signal transduction TarH PF02203.15 AAZ34451.1 - 1.2e-16 61.2 0.5 1.2e-16 61.2 0.5 3.7 3 2 1 4 4 4 1 Tar ligand binding domain homologue HAMP PF00672.25 AAZ34451.1 - 4.9e-07 30.0 9.5 2.7e-05 24.5 0.0 5.3 4 1 0 4 4 4 1 HAMP domain LAMTOR5 PF16672.5 AAZ34451.1 - 0.074 13.0 0.4 0.23 11.4 0.4 1.8 1 0 0 1 1 1 0 Ragulator complex protein LAMTOR5 IFT57 PF10498.9 AAZ34451.1 - 0.73 8.7 8.1 0.44 9.5 0.7 2.3 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DUF1664 PF07889.12 AAZ34451.1 - 2.9 7.9 11.1 5.8 7.0 0.9 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Sec34 PF04136.15 AAZ34451.1 - 5.5 6.9 6.9 3.1 7.7 0.4 3.2 2 2 0 3 3 3 0 Sec34-like family Fez1 PF06818.15 AAZ34451.1 - 9.6 6.6 12.3 0.31 11.5 1.8 2.5 3 0 0 3 3 3 0 Fez1 YceG PF02618.16 AAZ34452.1 - 3.1e-79 266.4 0.0 3.6e-79 266.2 0.0 1.0 1 0 0 1 1 1 1 YceG-like family DinB_2 PF12867.7 AAZ34452.1 - 0.092 13.3 0.1 0.98 9.9 0.0 2.4 1 1 1 2 2 2 0 DinB superfamily PDT PF00800.18 AAZ34453.1 - 4.5e-61 205.9 0.0 6.9e-61 205.2 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydratase CM_2 PF01817.21 AAZ34453.1 - 2.9e-21 75.6 0.7 2.9e-21 75.6 0.7 2.3 3 0 0 3 3 3 1 Chorismate mutase type II ACT PF01842.25 AAZ34453.1 - 2.6e-10 39.9 0.0 6.4e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 ACT domain HNHc_6 PF16784.5 AAZ34453.1 - 0.042 13.4 1.0 0.13 11.8 0.5 2.0 2 1 1 3 3 3 0 Putative HNHc nuclease CheW PF01584.19 AAZ34454.1 - 3.3e-63 211.4 0.0 6.8e-23 80.8 0.0 3.1 3 0 0 3 3 3 3 CheW-like domain Na_H_antiport_1 PF06965.12 AAZ34455.1 - 1e-142 475.5 30.2 1.1e-142 475.3 30.2 1.0 1 0 0 1 1 1 1 Na+/H+ antiporter 1 Romo1 PF10247.9 AAZ34455.1 - 0.0031 17.9 3.6 0.37 11.2 2.2 3.0 2 1 0 2 2 2 2 Reactive mitochondrial oxygen species modulator 1 ACR_tran PF00873.19 AAZ34456.1 - 5.2e-156 521.0 3.2 7.5e-156 520.5 3.2 1.1 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family Molybdopterin PF00384.22 AAZ34457.1 - 2e-84 284.0 0.0 2.4e-84 283.8 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 AAZ34457.1 - 1.1e-24 86.6 0.0 1.9e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 AAZ34457.1 - 2.6e-16 59.3 2.5 2.6e-16 59.3 2.5 1.9 2 0 0 2 2 2 1 Molybdopterin oxidoreductase Fe4S4 domain Fer2_BFD PF04324.15 AAZ34457.1 - 1.7e-07 31.4 4.5 4.1e-07 30.3 4.5 1.7 1 0 0 1 1 1 1 BFD-like [2Fe-2S] binding domain Acyltransferase PF01553.21 AAZ34458.1 - 7.4e-22 77.4 0.0 1.3e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase MFS_1 PF07690.16 AAZ34458.1 - 4.3e-14 52.2 34.7 4.3e-14 52.2 34.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2985 PF11204.8 AAZ34458.1 - 1 9.6 10.1 0.39 10.9 0.2 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2985) SOAR PF16533.5 AAZ34459.1 - 0.014 15.4 0.3 0.029 14.3 0.2 1.7 1 1 0 1 1 1 0 STIM1 Orai1-activating region Bunya_nucleocap PF00952.17 AAZ34459.1 - 0.028 14.4 0.1 0.039 14.0 0.1 1.1 1 0 0 1 1 1 0 Bunyavirus nucleocapsid (N) protein DivIC PF04977.15 AAZ34459.1 - 0.05 13.4 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 Septum formation initiator CHASE8 PF17152.4 AAZ34459.1 - 0.07 13.4 0.1 0.12 12.6 0.1 1.3 1 0 0 1 1 1 0 Periplasmic sensor domain Phage_integrase PF00589.22 AAZ34460.1 - 6.2e-43 146.5 0.0 2.2e-42 144.8 0.0 1.8 2 0 0 2 2 2 1 Phage integrase family Phage_int_SAM_1 PF02899.17 AAZ34460.1 - 5.1e-23 81.2 1.9 5.1e-23 81.2 1.9 2.3 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 AAZ34460.1 - 0.00011 22.6 0.8 0.0012 19.3 0.5 2.3 1 1 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 AAZ34460.1 - 0.023 15.0 0.0 0.047 14.0 0.0 1.5 1 0 0 1 1 1 0 Phage integrase SAM-like domain Ribosomal_S15 PF00312.22 AAZ34460.1 - 0.078 13.2 0.5 0.31 11.3 0.1 2.1 1 1 1 2 2 2 0 Ribosomal protein S15 ABC_tran PF00005.27 AAZ34461.1 - 7.7e-52 175.4 0.0 3.3e-30 105.4 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 AAZ34461.1 - 6.7e-13 49.1 1.4 0.002 18.0 0.1 3.2 2 1 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AAZ34461.1 - 0.0053 16.5 0.0 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AAZ34461.1 - 0.0058 16.5 0.4 0.022 14.7 0.1 2.0 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 AAZ34461.1 - 0.0061 16.0 0.1 0.81 9.1 0.1 2.8 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AAZ34461.1 - 0.051 14.1 0.0 0.084 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AAZ34461.1 - 0.058 13.7 0.8 0.9 9.8 0.0 2.9 4 0 0 4 4 4 0 AAA domain AAA_27 PF13514.6 AAZ34461.1 - 0.065 12.8 0.1 0.26 10.9 0.1 1.9 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 AAZ34461.1 - 0.12 12.4 0.4 3.1 7.8 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_15 PF13175.6 AAZ34461.1 - 0.26 11.0 0.0 0.47 10.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 AAZ34461.1 - 0.36 10.5 1.1 0.46 10.2 0.1 1.8 2 1 0 2 2 2 0 AAA domain HTH_31 PF13560.6 AAZ34463.1 - 3.9e-07 30.3 1.4 5.5e-07 29.8 1.4 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 AAZ34463.1 - 2.5e-05 24.2 0.1 3.4e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 AAZ34463.1 - 9.9e-05 22.3 0.1 0.00012 22.0 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 AAZ34463.1 - 0.0039 17.0 1.4 0.013 15.3 1.4 1.8 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 AAZ34463.1 - 0.031 14.2 0.2 0.04 13.9 0.2 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Pou PF00157.17 AAZ34463.1 - 0.069 13.1 0.2 0.097 12.7 0.2 1.4 1 1 0 1 1 1 0 Pou domain - N-terminal to homeobox domain DUF4447 PF14590.6 AAZ34463.1 - 0.099 12.4 0.0 0.11 12.3 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4447) Band_7 PF01145.25 AAZ34464.1 - 2.5e-28 99.3 1.2 4.2e-28 98.5 1.2 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 AAZ34464.1 - 0.014 15.1 0.1 0.029 14.1 0.1 1.6 1 1 1 2 2 2 0 SPFH domain-Band 7 family ILVD_EDD PF00920.21 AAZ34465.1 - 3.6e-173 576.9 0.3 4.1e-173 576.7 0.3 1.0 1 0 0 1 1 1 1 Dehydratase family MTS PF05175.14 AAZ34466.1 - 1e-18 67.5 0.0 2.9e-18 66.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 AAZ34466.1 - 2.9e-17 62.9 0.0 4.5e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAZ34466.1 - 4.6e-10 40.1 0.1 1.2e-09 38.7 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAZ34466.1 - 2e-08 34.8 0.1 7.9e-08 32.8 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 AAZ34466.1 - 3.5e-08 33.2 0.1 5.5e-08 32.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.18 AAZ34466.1 - 2.5e-07 30.6 0.0 4.3e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.12 AAZ34466.1 - 4.9e-07 30.4 0.0 1.2e-06 29.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain GidB PF02527.15 AAZ34466.1 - 2e-06 27.2 0.0 3.2e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_4 PF02390.17 AAZ34466.1 - 1.2e-05 24.9 0.0 3.7e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Cons_hypoth95 PF03602.15 AAZ34466.1 - 1.5e-05 24.7 0.0 2.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_18 PF12847.7 AAZ34466.1 - 2.7e-05 24.2 0.0 5.5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 AAZ34466.1 - 5.5e-05 22.8 0.0 8.1e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_23 PF13489.6 AAZ34466.1 - 0.0001 22.2 0.0 0.00036 20.4 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.16 AAZ34466.1 - 0.00045 20.0 0.0 0.00066 19.5 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltr_RsmB-F PF01189.17 AAZ34466.1 - 0.0015 18.2 0.0 0.0033 17.1 0.0 1.6 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F TehB PF03848.14 AAZ34466.1 - 0.0023 17.4 0.0 0.0036 16.7 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB N6_Mtase PF02384.16 AAZ34466.1 - 0.0024 17.2 0.0 0.0033 16.7 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_16 PF10294.9 AAZ34466.1 - 0.0026 17.5 0.0 0.0066 16.2 0.0 1.6 2 0 0 2 2 2 1 Lysine methyltransferase Ubie_methyltran PF01209.18 AAZ34466.1 - 0.0047 16.3 0.0 0.008 15.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 AAZ34466.1 - 0.0064 16.1 0.0 0.013 15.2 0.0 1.4 1 1 0 1 1 1 1 Nodulation protein S (NodS) PCMT PF01135.19 AAZ34466.1 - 0.0081 15.9 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 AAZ34466.1 - 0.01 15.9 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain rRNA_methylase PF06962.12 AAZ34466.1 - 0.11 12.5 0.0 0.51 10.3 0.0 2.2 2 1 1 3 3 3 0 Putative rRNA methylase Methyltransf_3 PF01596.17 AAZ34466.1 - 0.15 11.2 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase TPMT PF05724.11 AAZ34466.1 - 0.2 11.3 0.0 0.43 10.2 0.0 1.5 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) DUF3394 PF11874.8 AAZ34467.1 - 1.5 8.5 4.9 0.82 9.3 0.6 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3394) CobS PF02654.15 AAZ34468.1 - 4.5e-51 174.0 18.5 5.1e-51 173.8 18.5 1.0 1 0 0 1 1 1 1 Cobalamin-5-phosphate synthase DUF2754 PF10953.8 AAZ34468.1 - 0.4 11.0 3.2 0.25 11.6 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2754) CheW PF01584.19 AAZ34469.1 - 1.5e-10 40.9 0.0 1.9e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 CheW-like domain ABC_tran PF00005.27 AAZ34470.1 - 3e-29 102.3 0.0 5.4e-29 101.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 AAZ34470.1 - 3.8e-16 59.6 13.6 2.5e-15 56.9 12.9 2.2 2 0 0 2 2 2 1 ABC transporter transmembrane region AAA_21 PF13304.6 AAZ34470.1 - 3.9e-07 30.2 0.0 0.018 14.9 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAZ34470.1 - 0.00015 21.3 0.0 0.0027 17.2 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 AAZ34470.1 - 0.0044 17.2 0.0 0.022 14.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 AAZ34470.1 - 0.0044 15.9 0.2 0.31 9.8 0.1 3.2 4 0 0 4 4 4 1 Predicted ATPase of the ABC class AAA_16 PF13191.6 AAZ34470.1 - 0.0061 17.0 0.8 0.02 15.3 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 AAZ34470.1 - 0.0062 16.6 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 AAZ34470.1 - 0.029 14.1 0.0 0.07 12.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 AAZ34470.1 - 0.052 13.1 0.0 3.9 7.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 AAZ34470.1 - 0.061 13.2 0.0 0.21 11.5 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA_23 PF13476.6 AAZ34470.1 - 0.11 13.0 0.1 0.2 12.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain HATPase_c PF02518.26 AAZ34471.1 - 6.5e-17 62.1 0.0 1.1e-16 61.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAZ34471.1 - 2.2e-06 27.6 0.4 8.5e-06 25.7 0.1 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 AAZ34471.1 - 0.00076 19.3 0.0 0.0017 18.2 0.0 1.6 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AAZ34471.1 - 0.0058 16.6 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_5 PF14501.6 AAZ34471.1 - 0.034 14.0 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 GHKL domain SRA1 PF07304.11 AAZ34471.1 - 0.075 12.8 0.2 0.16 11.8 0.2 1.5 1 0 0 1 1 1 0 Steroid receptor RNA activator (SRA1) Ribonuc_red_lgC PF02867.15 AAZ34472.1 - 5.5e-181 602.7 0.0 7.8e-181 602.1 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain ATP-cone PF03477.16 AAZ34472.1 - 4.4e-28 97.7 0.5 2.4e-18 66.5 0.2 3.0 3 0 0 3 3 3 2 ATP cone domain Ribonuc_red_lgN PF00317.21 AAZ34472.1 - 1.9e-22 79.0 0.1 5.3e-22 77.6 0.1 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain AAA_3 PF07726.11 AAZ34473.1 - 6.7e-60 200.7 0.0 9.8e-60 200.1 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 AAZ34473.1 - 6.7e-21 73.9 0.2 1.3e-20 73.0 0.2 1.5 1 0 0 1 1 1 1 AAA lid domain AAA_5 PF07728.14 AAZ34473.1 - 7.7e-12 45.4 0.0 4.5e-11 42.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 AAZ34473.1 - 1.5e-05 24.5 0.1 0.011 15.1 0.1 2.2 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI MCM PF00493.23 AAZ34473.1 - 2.1e-05 23.8 0.0 3.3e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain RuvB_N PF05496.12 AAZ34473.1 - 0.00025 20.8 0.0 0.042 13.6 0.1 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 AAZ34473.1 - 0.00056 20.3 0.0 0.0024 18.3 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 AAZ34473.1 - 0.02 14.6 0.0 0.1 12.3 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.6 AAZ34473.1 - 0.085 13.4 0.0 0.24 11.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 AAZ34473.1 - 0.1 12.8 0.0 0.31 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain Response_reg PF00072.24 AAZ34474.1 - 3.9e-29 101.1 0.8 1.2e-27 96.2 0.2 2.8 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 AAZ34474.1 - 1.5e-28 99.5 0.0 3.9e-28 98.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAZ34474.1 - 6.6e-25 86.9 2.9 6e-22 77.5 0.0 4.3 1 1 1 2 2 2 1 His Kinase A (phospho-acceptor) domain DUF2222 PF09984.9 AAZ34474.1 - 7.6e-19 68.1 0.0 1.6e-18 67.0 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised signal transduction histidine kinase domain (DUF2222) HAMP PF00672.25 AAZ34474.1 - 1.1e-10 41.8 0.3 3.4e-10 40.1 0.3 2.0 1 0 0 1 1 1 1 HAMP domain Hpt PF01627.23 AAZ34474.1 - 1.9e-10 40.8 4.2 1.9e-10 40.8 4.2 3.1 2 0 0 2 2 2 1 Hpt domain Syntaxin-6_N PF09177.11 AAZ34474.1 - 0.0029 18.1 3.3 2.2 8.9 0.1 3.5 3 0 0 3 3 3 2 Syntaxin 6, N-terminal HATPase_c_3 PF13589.6 AAZ34474.1 - 0.0037 17.1 0.2 0.021 14.6 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase sCache_3_2 PF17203.4 AAZ34474.1 - 0.14 12.3 0.2 6.7 6.8 0.0 2.5 2 0 0 2 2 2 0 Single cache domain 3 TFIIF_beta PF02270.15 AAZ34474.1 - 0.18 12.0 0.1 1.1 9.5 0.0 2.2 2 0 0 2 2 2 0 TFIIF, beta subunit HTH domain Snapin_Pallidin PF14712.6 AAZ34474.1 - 9 6.8 10.3 7.9 7.0 1.8 3.5 4 0 0 4 4 3 0 Snapin/Pallidin Sel1 PF08238.12 AAZ34475.1 - 8.7e-07 29.4 0.4 8.7e-07 29.4 0.4 3.5 3 1 0 3 3 3 1 Sel1 repeat DUF4350 PF14258.6 AAZ34476.1 - 1.2e-09 38.4 0.6 4.8e-09 36.5 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4350) Ribosomal_S10 PF00338.22 AAZ34477.1 - 2.8e-35 120.5 0.3 3.4e-35 120.2 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Epimerase PF01370.21 AAZ34478.1 - 3.1e-20 72.7 0.0 4.1e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AAZ34478.1 - 1.6e-15 57.3 0.0 1.8e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 AAZ34478.1 - 1.5e-13 50.4 0.0 2e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 AAZ34478.1 - 3e-09 36.5 0.0 1.4e-07 30.9 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 AAZ34478.1 - 2.6e-07 30.7 0.0 3.5e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 AAZ34478.1 - 2.9e-07 29.9 0.0 4.1e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 AAZ34478.1 - 2e-05 23.9 0.0 4.2e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 AAZ34478.1 - 0.38 10.6 1.5 12 5.7 1.5 2.8 1 1 0 1 1 1 0 KR domain PAP2 PF01569.21 AAZ34479.1 - 7.9e-10 38.6 10.0 1.3e-09 37.9 10.0 1.3 1 0 0 1 1 1 1 PAP2 superfamily Cytochrom_B558a PF05038.13 AAZ34479.1 - 0.14 11.7 0.4 0.23 11.0 0.4 1.2 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit DAO PF01266.24 AAZ34480.1 - 1.6e-69 235.1 6.0 2e-69 234.8 6.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AAZ34480.1 - 2.1e-05 24.6 0.1 5.2e-05 23.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AAZ34480.1 - 0.00015 21.1 0.0 0.0012 18.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AAZ34480.1 - 0.00022 20.7 0.6 0.004 16.6 0.6 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AAZ34480.1 - 0.00022 20.5 4.4 0.00034 19.8 4.4 1.3 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.16 AAZ34480.1 - 0.0019 17.9 0.0 0.0032 17.1 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Thi4 PF01946.17 AAZ34480.1 - 0.0019 17.5 0.2 0.0031 16.8 0.2 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 AAZ34480.1 - 0.0022 17.3 0.6 0.0039 16.5 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 AAZ34480.1 - 0.0047 16.1 0.2 0.011 14.9 0.1 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 AAZ34480.1 - 0.0073 16.8 0.5 0.051 14.1 1.3 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 AAZ34480.1 - 0.012 15.5 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 AAZ34480.1 - 0.015 14.1 1.6 0.034 12.8 0.8 1.9 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.14 AAZ34480.1 - 0.018 13.9 0.5 0.029 13.2 0.5 1.3 1 0 0 1 1 1 0 Tryptophan halogenase DEAD PF00270.29 AAZ34481.1 - 3.3e-45 154.0 0.0 7.3e-45 152.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DbpA PF03880.15 AAZ34481.1 - 4.5e-26 90.7 0.2 9.9e-26 89.5 0.2 1.6 1 0 0 1 1 1 1 DbpA RNA binding domain Helicase_C PF00271.31 AAZ34481.1 - 9.1e-25 87.2 0.2 1e-22 80.6 0.1 3.1 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 AAZ34481.1 - 8.3e-07 29.2 0.0 1.4e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ESX-1_EspG PF14011.6 AAZ34481.1 - 0.013 15.1 0.2 0.026 14.1 0.2 1.4 1 0 0 1 1 1 0 EspG family CMS1 PF14617.6 AAZ34481.1 - 0.014 14.8 0.0 0.025 13.9 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit PRAI PF00697.22 AAZ34481.1 - 0.034 13.9 0.2 0.057 13.2 0.2 1.3 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase ERCC3_RAD25_C PF16203.5 AAZ34481.1 - 0.058 12.6 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase AAA_19 PF13245.6 AAZ34481.1 - 0.063 13.6 0.0 3 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain PPDK_N PF01326.19 AAZ34482.1 - 2e-118 395.4 0.0 2.7e-118 395.0 0.0 1.2 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers_C PF02896.18 AAZ34482.1 - 9e-63 212.1 0.0 1.6e-62 211.3 0.0 1.4 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilizers PF00391.23 AAZ34482.1 - 1.2e-26 92.2 0.5 2.5e-26 91.2 0.5 1.6 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain RHH_1 PF01402.21 AAZ34483.1 - 1.6e-09 37.4 0.1 1.6e-09 37.4 0.1 1.5 2 0 0 2 2 2 1 Ribbon-helix-helix protein, copG family Arc PF03869.14 AAZ34483.1 - 0.0015 18.3 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 Arc-like DNA binding domain PSK_trans_fac PF07704.11 AAZ34483.1 - 0.002 18.9 0.9 0.0039 17.9 0.9 1.5 1 1 0 1 1 1 1 Rv0623-like transcription factor RHH_5 PF07878.11 AAZ34483.1 - 0.0026 17.6 0.6 0.0046 16.8 0.1 1.7 2 0 0 2 2 2 1 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 TraY PF05509.11 AAZ34483.1 - 0.012 15.7 0.1 0.016 15.2 0.1 1.2 1 0 0 1 1 1 0 TraY domain DUF2533 PF10752.9 AAZ34483.1 - 0.014 15.8 0.1 0.068 13.6 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2533) CopG_antitoxin PF12441.8 AAZ34483.1 - 0.13 12.8 0.2 3.4 8.3 0.0 2.1 2 0 0 2 2 2 0 CopG antitoxin of type II toxin-antitoxin system Condensation PF00668.20 AAZ34484.1 - 4.1e-262 869.7 0.0 4.7e-98 328.8 0.0 3.1 3 0 0 3 3 3 3 Condensation domain AMP-binding PF00501.28 AAZ34484.1 - 2.9e-178 592.8 0.0 1.3e-96 323.8 0.0 3.1 3 1 0 3 3 3 2 AMP-binding enzyme PP-binding PF00550.25 AAZ34484.1 - 1.5e-29 102.2 0.6 3.2e-13 49.8 0.0 3.3 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 AAZ34484.1 - 3.2e-24 85.7 0.1 4.4e-13 50.0 0.0 2.8 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain SBP_bac_5 PF00496.22 AAZ34484.1 - 0.027 13.4 0.0 0.054 12.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle AATase PF07247.12 AAZ34484.1 - 0.09 11.3 0.0 0.39 9.2 0.0 1.9 2 0 0 2 2 2 0 Alcohol acetyltransferase Inhibitor_I42 PF09394.10 AAZ34485.1 - 2.3e-22 79.2 0.1 2.8e-22 78.9 0.1 1.1 1 0 0 1 1 1 1 Chagasin family peptidase inhibitor I42 Bmt2 PF11968.8 AAZ34485.1 - 0.2 11.5 0.0 0.21 11.4 0.0 1.1 1 0 0 1 1 1 0 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Y1_Tnp PF01797.16 AAZ34487.1 - 0.028 14.5 0.1 0.052 13.7 0.1 1.6 1 1 0 1 1 1 0 Transposase IS200 like DUF2235 PF09994.9 AAZ34487.1 - 0.08 12.3 0.1 0.096 12.0 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) YscJ_FliF PF01514.17 AAZ34488.1 - 9.3e-70 234.2 0.9 2.6e-69 232.8 0.2 2.0 1 1 1 2 2 2 1 Secretory protein of YscJ/FliF family YscJ_FliF_C PF08345.11 AAZ34488.1 - 3.9e-46 157.1 2.6 4.9e-46 156.8 0.4 2.3 2 0 0 2 2 2 1 Flagellar M-ring protein C-terminal Lipase_GDSL_2 PF13472.6 AAZ34489.1 - 0.00012 22.5 0.1 0.00022 21.7 0.1 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Peptidase_M75 PF09375.10 AAZ34490.1 - 2.3e-99 332.5 0.8 2.6e-99 332.3 0.5 1.2 1 1 0 1 1 1 1 Imelysin DUF3391 PF11871.8 AAZ34490.1 - 0.053 14.1 0.5 0.12 13.0 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) DEC-1_N PF04625.13 AAZ34490.1 - 0.54 9.2 11.0 0.79 8.7 11.0 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region CAP_N PF01213.19 AAZ34490.1 - 2.7 7.4 6.5 4.8 6.6 6.5 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal ABC_tran PF00005.27 AAZ34491.1 - 2.5e-32 112.3 0.0 4.1e-32 111.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAZ34491.1 - 9e-08 32.3 0.0 0.0002 21.3 0.0 2.4 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAZ34491.1 - 5.3e-06 26.0 0.0 0.012 15.1 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_membrane PF00664.23 AAZ34491.1 - 7.1e-06 25.9 0.6 1.2e-05 25.1 0.6 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_22 PF13401.6 AAZ34491.1 - 8.8e-05 22.8 0.0 0.0089 16.3 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_15 PF13175.6 AAZ34491.1 - 0.00025 20.9 0.0 0.00041 20.2 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_16 PF13191.6 AAZ34491.1 - 0.0004 20.8 1.9 0.0007 20.0 0.2 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 AAZ34491.1 - 0.0037 17.0 0.0 0.009 15.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 AAZ34491.1 - 0.0087 15.8 0.0 0.059 13.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 AAZ34491.1 - 0.0089 16.6 0.0 0.018 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain G-alpha PF00503.20 AAZ34491.1 - 0.017 14.3 0.0 0.026 13.7 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit DLIC PF05783.11 AAZ34491.1 - 0.021 13.7 0.0 0.029 13.2 0.0 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) KAP_NTPase PF07693.14 AAZ34491.1 - 0.022 14.0 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain DUF2794 PF10984.8 AAZ34491.1 - 0.022 14.9 0.0 0.058 13.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2794) SRP54 PF00448.22 AAZ34491.1 - 0.022 14.4 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NACHT PF05729.12 AAZ34491.1 - 0.041 13.8 0.0 0.086 12.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 AAZ34491.1 - 0.042 13.4 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 AAZ34491.1 - 0.059 13.3 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Zeta_toxin PF06414.12 AAZ34491.1 - 0.063 12.6 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.14 AAZ34491.1 - 0.064 13.3 0.0 0.19 11.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 AAZ34491.1 - 0.08 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 AAZ34491.1 - 0.13 11.9 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 AAZ34491.1 - 0.2 11.7 0.0 0.37 10.9 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain Transposase_mut PF00872.18 AAZ34492.1 - 1.5e-117 392.7 0.0 1.9e-117 392.3 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ34492.1 - 7.7e-05 23.0 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain DUF4844 PF16133.5 AAZ34492.1 - 0.23 12.0 0.0 0.55 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) DJ-1_PfpI PF01965.24 AAZ34493.1 - 1.9e-16 60.3 0.0 4e-16 59.2 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 AAZ34493.1 - 4.6e-07 29.7 0.0 5.4e-05 23.0 0.0 2.1 1 1 0 1 1 1 1 ThiJ/PfpI family-like Aminotran_1_2 PF00155.21 AAZ34494.1 - 6.8e-08 32.1 0.0 8.3e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF2623 PF11115.8 AAZ34494.1 - 0.12 12.5 0.0 0.33 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2623) FHIPEP PF00771.20 AAZ34495.1 - 5.3e-208 692.7 6.6 6.1e-208 692.5 6.6 1.0 1 0 0 1 1 1 1 FHIPEP family DUF4432 PF14486.6 AAZ34496.1 - 1.6e-112 375.2 0.0 1.9e-112 375.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4432) ACP_syn_III PF08545.10 AAZ34497.1 - 6.4e-08 32.3 0.0 1.3e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.10 AAZ34497.1 - 2.4e-06 27.6 0.0 1.3e-05 25.3 0.0 2.2 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal LysR_substrate PF03466.20 AAZ34499.1 - 3.1e-41 141.1 2.8 3.1e-41 141.1 2.8 1.5 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ34499.1 - 1.2e-19 70.0 0.9 2.5e-19 68.9 0.9 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_8 PF02954.19 AAZ34499.1 - 0.0042 16.8 0.0 0.0096 15.7 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family HTH_Tnp_ISL3 PF13542.6 AAZ34499.1 - 0.013 14.9 1.0 0.037 13.4 0.0 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_30 PF13556.6 AAZ34499.1 - 0.019 14.7 0.1 0.05 13.4 0.1 1.7 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_psq PF05225.16 AAZ34499.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 helix-turn-helix, Psq domain Hairpins PF04877.12 AAZ34500.1 - 2.1e-113 379.0 27.1 2.5e-113 378.8 27.1 1.1 1 0 0 1 1 1 1 HrpZ HATPase_c PF02518.26 AAZ34501.1 - 1.3e-22 80.4 0.1 1.1e-21 77.4 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAZ34501.1 - 4e-11 42.8 1.0 1e-10 41.5 0.0 2.2 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 AAZ34501.1 - 0.00094 19.0 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 GHKL domain HATPase_c_2 PF13581.6 AAZ34501.1 - 0.012 15.6 0.0 0.035 14.1 0.0 1.9 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Epimerase PF01370.21 AAZ34502.1 - 6.7e-34 117.4 0.0 8.9e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 AAZ34502.1 - 6.7e-21 74.5 0.0 9.2e-21 74.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 AAZ34502.1 - 1.8e-19 70.3 0.0 2.4e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 AAZ34502.1 - 9.2e-19 68.0 0.0 8.3e-18 64.9 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 AAZ34502.1 - 5.8e-18 65.0 0.1 2.8e-11 43.1 0.0 2.3 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 AAZ34502.1 - 3.9e-16 59.0 0.0 4.9e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 AAZ34502.1 - 4.3e-14 52.3 0.1 4.1e-12 45.8 0.1 2.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 AAZ34502.1 - 1.3e-09 38.0 0.1 2.3e-08 33.9 0.3 2.1 2 0 0 2 2 2 1 NmrA-like family KR PF08659.10 AAZ34502.1 - 0.00016 21.6 0.8 0.04 13.8 0.8 2.3 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 AAZ34502.1 - 0.012 15.8 0.7 0.035 14.3 0.7 1.8 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 AAZ34502.1 - 0.022 15.2 0.1 0.065 13.7 0.1 1.9 2 0 0 2 2 1 0 Semialdehyde dehydrogenase, NAD binding domain GATase_4 PF13230.6 AAZ34502.1 - 0.15 10.9 0.0 0.62 8.9 0.0 1.8 2 0 0 2 2 2 0 Glutamine amidotransferases class-II ATP-synt_ab PF00006.25 AAZ34504.1 - 6.4e-68 228.6 0.0 8.2e-68 228.2 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain T3SS_ATPase_C PF18269.1 AAZ34504.1 - 2e-24 85.2 0.1 4.1e-24 84.2 0.1 1.5 1 0 0 1 1 1 1 T3SS EscN ATPase C-terminal domain ATP-synt_ab_N PF02874.23 AAZ34504.1 - 8.9e-07 29.3 0.0 2.2e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Nitro_FeMo-Co PF02579.17 AAZ34504.1 - 0.006 16.9 0.0 0.19 12.1 0.0 2.3 2 0 0 2 2 2 1 Dinitrogenase iron-molybdenum cofactor AAA_28 PF13521.6 AAZ34504.1 - 0.0076 16.5 0.2 0.042 14.1 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 AAZ34504.1 - 0.014 16.0 0.0 0.033 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 AAZ34504.1 - 0.017 15.5 4.6 0.11 12.9 2.3 2.8 2 1 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.6 AAZ34504.1 - 0.034 14.6 0.0 0.072 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 AAZ34504.1 - 0.059 13.8 0.3 0.22 11.9 0.1 2.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 AAZ34504.1 - 0.065 13.1 1.7 0.56 10.1 0.2 2.8 2 1 0 2 2 2 0 NACHT domain AAA_22 PF13401.6 AAZ34504.1 - 0.089 13.1 0.1 0.22 11.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AAZ34504.1 - 0.11 12.3 0.2 0.3 10.8 0.2 1.7 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 AAZ34504.1 - 0.11 13.0 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter ATPase_2 PF01637.18 AAZ34504.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 AAZ34504.1 - 0.41 10.2 3.4 1 8.9 1.3 2.5 2 1 0 2 2 2 0 AAA domain MCPsignal PF00015.21 AAZ34505.1 - 3.3e-16 59.6 1.1 5.7e-16 58.8 1.1 1.3 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain dCache_1 PF02743.18 AAZ34505.1 - 2.1e-07 31.0 0.0 6.6e-07 29.4 0.0 1.7 2 0 0 2 2 2 1 Cache domain Noelin-1 PF12308.8 AAZ34505.1 - 0.18 11.8 0.5 16 5.6 0.1 2.3 1 1 1 2 2 2 0 Neurogenesis glycoprotein DUF2784 PF10861.8 AAZ34506.1 - 8.5e-39 132.1 3.3 9.8e-39 131.9 3.3 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF2784) DUF962 PF06127.11 AAZ34506.1 - 1.6 8.9 4.7 3.6 7.7 3.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF962) Phage_holin_3_6 PF07332.11 AAZ34506.1 - 5.4 7.1 8.8 11 6.1 4.1 2.1 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Transposase_mut PF00872.18 AAZ34507.1 - 1.5e-117 392.7 0.0 1.9e-117 392.3 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ34507.1 - 7.7e-05 23.0 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain DUF4844 PF16133.5 AAZ34507.1 - 0.23 12.0 0.0 0.55 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) CSD PF00313.22 AAZ34509.1 - 1.6e-28 98.4 2.3 1.9e-28 98.1 2.3 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 AAZ34509.1 - 0.0018 17.9 1.0 0.0028 17.3 1.0 1.4 1 0 0 1 1 1 1 Ribonuclease B OB domain CusF_Ec PF11604.8 AAZ34509.1 - 0.036 14.0 0.2 0.05 13.6 0.2 1.2 1 0 0 1 1 1 0 Copper binding periplasmic protein CusF GspL_C PF12693.7 AAZ34511.1 - 0.93 9.3 5.0 1 9.2 5.0 1.1 1 0 0 1 1 1 0 GspL periplasmic domain HATPase_c PF02518.26 AAZ34512.1 - 9.9e-17 61.5 0.0 2e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAZ34512.1 - 3.3e-14 52.6 1.7 3.3e-14 52.6 1.7 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 AAZ34512.1 - 3.2e-05 23.9 0.2 0.00013 21.9 0.2 2.1 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 AAZ34512.1 - 0.0098 15.9 0.0 0.025 14.6 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_7 PF12860.7 AAZ34512.1 - 0.012 15.7 0.2 0.045 13.9 0.0 2.0 2 0 0 2 2 2 0 PAS fold HATPase_c_2 PF13581.6 AAZ34512.1 - 0.022 14.7 0.0 0.053 13.5 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain SHR3_chaperone PF08229.11 AAZ34512.1 - 0.14 11.1 0.5 0.36 9.8 0.5 1.6 1 0 0 1 1 1 0 ER membrane protein SH3 DUF3112 PF11309.8 AAZ34513.1 - 0.2 11.1 0.0 0.21 11.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) UvrD_C PF13361.6 AAZ34514.1 - 6.9e-78 262.5 0.1 1.7e-77 261.2 0.1 1.6 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 AAZ34514.1 - 7.4e-73 245.8 0.0 1.9e-72 244.5 0.0 1.7 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 AAZ34514.1 - 2.1e-31 109.3 0.0 5.4e-31 107.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 AAZ34514.1 - 3.8e-11 42.6 0.0 1e-10 41.3 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 AAZ34514.1 - 3.6e-09 36.6 0.4 4e-05 23.4 0.2 2.6 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 AAZ34514.1 - 2.5e-05 24.2 0.0 0.05 13.3 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase Exonuc_V_gamma PF04257.14 AAZ34514.1 - 8.2e-05 21.0 0.0 0.00014 20.2 0.0 1.4 1 0 0 1 1 1 1 Exodeoxyribonuclease V, gamma subunit AAA_12 PF13087.6 AAZ34514.1 - 0.0022 17.6 0.0 3.2 7.3 0.0 2.9 2 1 1 3 3 3 2 AAA domain AAA_22 PF13401.6 AAZ34514.1 - 0.013 15.7 0.1 0.57 10.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain RHH_1 PF01402.21 AAZ34514.1 - 0.19 11.7 1.2 0.99 9.4 0.1 2.7 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family DUF423 PF04241.15 AAZ34515.1 - 9.2e-30 102.7 7.8 1.4e-29 102.1 7.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF423) Ribosomal_S30AE PF02482.19 AAZ34516.1 - 5e-08 33.6 0.1 6.5e-08 33.2 0.1 1.2 1 0 0 1 1 1 1 Sigma 54 modulation protein / S30EA ribosomal protein DNA_pol_B PF00136.21 AAZ34517.1 - 3.4e-41 141.4 0.0 9.4e-40 136.7 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 AAZ34517.1 - 9.5e-12 44.7 0.0 5.1e-10 39.0 0.0 2.5 1 1 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B_2 PF03175.13 AAZ34517.1 - 0.0001 21.3 0.0 0.025 13.5 0.0 2.1 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral MatE PF01554.18 AAZ34518.1 - 4.5e-35 120.7 27.6 5.6e-21 74.9 12.2 2.2 2 0 0 2 2 2 2 MatE Histone_HNS PF00816.21 AAZ34519.1 - 0.0027 18.5 0.2 0.004 17.9 0.2 1.3 1 0 0 1 1 1 1 H-NS histone family Ntox44 PF15607.6 AAZ34520.1 - 2.2e-26 92.1 0.0 3.4e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial toxin 44 PAAR_motif PF05488.13 AAZ34520.1 - 3.5e-17 62.3 5.5 1.4e-11 44.4 3.0 3.1 2 1 1 3 3 3 2 PAAR motif PBSX_XtrA PF17356.2 AAZ34520.1 - 0.00024 20.9 0.0 0.69 9.9 0.0 2.3 2 0 0 2 2 2 2 Phage-like element PBSX protein XtrA Inositol_P PF00459.25 AAZ34521.1 - 6.8e-68 229.1 0.0 7.9e-68 228.9 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.20 AAZ34521.1 - 0.032 13.7 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase, N-terminal domain Phage_GPD PF05954.11 AAZ34522.1 - 6.7e-19 68.3 0.1 7.6e-19 68.1 0.1 1.0 1 0 0 1 1 1 1 Phage late control gene D protein (GPD) Aldedh PF00171.22 AAZ34523.1 - 2.4e-170 567.0 0.1 2.7e-170 566.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 AAZ34523.1 - 0.038 13.4 0.0 0.22 10.9 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) Condensation PF00668.20 AAZ34524.1 - 0 1313.0 0.0 4.4e-110 368.5 1.5 4.1 4 0 0 4 4 4 4 Condensation domain AMP-binding PF00501.28 AAZ34524.1 - 0 1221.1 0.0 7.5e-103 344.4 0.0 4.2 4 0 0 4 4 4 4 AMP-binding enzyme PP-binding PF00550.25 AAZ34524.1 - 1.2e-62 208.2 4.4 6.5e-14 52.0 0.1 5.9 5 0 0 5 5 5 4 Phosphopantetheine attachment site AMP-binding_C PF13193.6 AAZ34524.1 - 3.7e-43 146.4 1.1 5.4e-14 52.9 0.0 4.8 4 0 0 4 4 4 4 AMP-binding enzyme C-terminal domain BrnA_antitoxin PF14384.6 AAZ34524.1 - 0.0016 18.9 2.4 0.71 10.4 0.5 2.9 2 0 0 2 2 2 2 BrnA antitoxin of type II toxin-antitoxin system AMP-binding_C_2 PF14535.6 AAZ34524.1 - 0.0047 17.2 0.1 0.015 15.6 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF2782 PF11191.8 AAZ34525.1 - 9.6e-22 77.0 0.0 1.1e-21 76.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2782) RNase_T PF00929.24 AAZ34526.1 - 2.1e-28 99.9 0.0 2.7e-28 99.6 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 AAZ34526.1 - 4.9e-06 26.6 0.1 3.6e-05 23.8 0.1 2.0 1 1 0 1 1 1 1 3' exoribonuclease, RNase T-like RNase_H_2 PF13482.6 AAZ34526.1 - 0.028 14.4 0.0 0.068 13.2 0.0 1.7 1 1 0 1 1 1 0 RNase_H superfamily MannoseP_isomer PF01050.18 AAZ34527.1 - 1.1e-74 249.3 0.4 1.9e-74 248.6 0.4 1.4 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase NTP_transferase PF00483.23 AAZ34527.1 - 1.8e-72 243.9 0.0 3.3e-72 243.0 0.0 1.4 2 0 0 2 2 2 1 Nucleotidyl transferase Cupin_2 PF07883.11 AAZ34527.1 - 4.7e-10 39.0 0.0 1.7e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 Cupin domain NTP_transf_3 PF12804.7 AAZ34527.1 - 5.5e-09 36.6 0.0 1.1e-08 35.6 0.0 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain AraC_binding PF02311.19 AAZ34527.1 - 0.046 13.6 0.1 0.087 12.7 0.1 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain GreA_GreB_N PF03449.15 AAZ34528.1 - 7.3e-24 83.7 0.7 1.2e-23 83.1 0.7 1.3 1 0 0 1 1 1 1 Transcription elongation factor, N-terminal GreA_GreB PF01272.19 AAZ34528.1 - 1.2e-21 76.4 0.0 1.8e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 Transcription elongation factor, GreA/GreB, C-term SBP_bac_1 PF01547.25 AAZ34529.1 - 3.3e-32 112.7 1.9 4.4e-32 112.3 1.9 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 AAZ34529.1 - 3.3e-29 102.6 2.3 4.2e-29 102.3 2.3 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 AAZ34529.1 - 0.0089 15.8 1.0 0.13 11.9 1.0 2.3 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AAZ34529.1 - 0.082 12.3 0.1 2.4 7.5 0.0 2.4 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein LysE PF01810.18 AAZ34530.1 - 3.6e-45 153.8 14.3 4.2e-45 153.6 14.3 1.0 1 0 0 1 1 1 1 LysE type translocator CAAD PF14159.6 AAZ34530.1 - 0.082 12.7 0.2 0.27 11.1 0.1 2.0 1 1 1 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Peptidase_M20 PF01546.28 AAZ34531.1 - 3.5e-40 137.9 0.1 4.2e-40 137.6 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AAZ34531.1 - 5.3e-26 90.7 0.0 1e-25 89.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 AAZ34531.1 - 0.0027 17.4 0.0 0.0058 16.3 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 BNR_2 PF13088.6 AAZ34531.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 BNR repeat-like domain Bac_luciferase PF00296.20 AAZ34532.1 - 3.6e-41 141.6 0.3 4.5e-41 141.3 0.3 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Glyco_tranf_2_4 PF13704.6 AAZ34532.1 - 0.044 14.3 0.2 0.4 11.2 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 BPD_transp_1 PF00528.22 AAZ34533.1 - 7.9e-47 159.4 13.7 7.9e-47 159.4 13.7 1.5 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component NAD_binding_10 PF13460.6 AAZ34534.1 - 8.9e-25 87.6 0.5 1.7e-24 86.7 0.5 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 AAZ34534.1 - 1.3e-20 74.0 0.0 2.4e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 AAZ34534.1 - 1.3e-05 24.5 0.0 3.1e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 AAZ34534.1 - 3.8e-05 22.9 0.0 9.3e-05 21.6 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 AAZ34534.1 - 0.00015 21.4 0.0 0.00037 20.0 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 AAZ34534.1 - 0.00018 21.8 0.1 0.00054 20.2 0.1 2.0 2 1 0 2 2 2 1 TrkA-N domain KR PF08659.10 AAZ34534.1 - 0.0016 18.4 0.4 0.0047 16.8 0.4 1.9 1 1 0 1 1 1 1 KR domain F420_oxidored PF03807.17 AAZ34534.1 - 0.0077 16.8 0.1 0.025 15.1 0.1 2.0 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.17 AAZ34534.1 - 0.042 12.9 0.3 2 7.4 0.2 2.5 2 1 0 2 2 2 0 RmlD substrate binding domain DapB_N PF01113.20 AAZ34534.1 - 0.057 13.5 0.1 0.096 12.8 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.15 AAZ34534.1 - 0.11 11.7 0.0 0.24 10.5 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Peptidase_M22 PF00814.25 AAZ34535.1 - 3.5e-103 345.0 0.0 4.1e-103 344.8 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 AAZ34535.1 - 0.0061 16.3 0.0 0.023 14.3 0.0 1.8 2 0 0 2 2 2 1 Carbamoyltransferase N-terminus BPD_transp_1 PF00528.22 AAZ34536.1 - 1e-24 87.3 13.8 1.9e-24 86.4 13.8 1.4 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 AAZ34536.1 - 9.4e-06 25.5 0.3 9.4e-06 25.5 0.3 3.7 4 0 0 4 4 4 2 N-terminal TM domain of oligopeptide transport permease C BPD_transp_1 PF00528.22 AAZ34537.1 - 1.5e-16 60.7 21.4 1.5e-16 60.7 21.4 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component Flp1_like PF16982.5 AAZ34537.1 - 0.062 12.7 0.8 0.16 11.4 0.8 1.7 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain Abhydrolase_6 PF12697.7 AAZ34538.1 - 9.6e-21 75.4 3.6 1.2e-20 75.1 3.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AAZ34538.1 - 9.7e-21 74.6 0.1 2.1e-19 70.2 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AAZ34538.1 - 2.7e-16 59.6 0.0 3.8e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 AAZ34538.1 - 1.5e-07 31.2 0.0 0.00046 19.8 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_4 PF08386.10 AAZ34538.1 - 5e-06 26.6 0.0 8.5e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Thioesterase PF00975.20 AAZ34538.1 - 9.1e-05 22.7 0.0 0.00019 21.6 0.0 1.4 2 0 0 2 2 2 1 Thioesterase domain FSH1 PF03959.13 AAZ34538.1 - 0.00049 19.8 0.0 0.0034 17.1 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) BAAT_C PF08840.11 AAZ34538.1 - 0.0041 17.1 0.0 0.023 14.6 0.0 1.9 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 AAZ34538.1 - 0.0058 16.3 0.0 0.01 15.5 0.0 1.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 AAZ34538.1 - 0.01 15.3 0.0 0.1 12.0 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family PGAP1 PF07819.13 AAZ34538.1 - 0.011 15.5 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Esterase PF00756.20 AAZ34538.1 - 0.022 14.4 0.1 0.054 13.1 0.0 1.5 2 0 0 2 2 2 0 Putative esterase UPF0227 PF05728.12 AAZ34538.1 - 0.062 13.2 0.0 0.41 10.6 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Abhydrolase_2 PF02230.16 AAZ34538.1 - 0.1 12.4 0.0 0.49 10.2 0.0 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF726 PF05277.12 AAZ34538.1 - 0.19 10.6 0.3 0.37 9.7 0.1 1.6 1 1 0 2 2 2 0 Protein of unknown function (DUF726) ETF PF01012.21 AAZ34539.1 - 6.8e-17 61.9 1.1 1.1e-16 61.2 1.1 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain MFS_1 PF07690.16 AAZ34540.1 - 5.8e-33 114.3 52.8 7.6e-30 104.0 26.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AAZ34540.1 - 1.8e-24 86.4 22.7 2.5e-24 86.0 22.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Nuc_H_symport PF03825.16 AAZ34540.1 - 0.069 12.1 16.7 0.0054 15.8 6.2 2.4 2 1 0 2 2 2 0 Nucleoside H+ symporter Pyr_redox_2 PF07992.14 AAZ34541.1 - 1.4e-61 208.4 0.0 1.6e-61 208.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAZ34541.1 - 1e-18 67.7 3.0 4e-17 62.5 0.2 3.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 AAZ34541.1 - 1.2e-10 41.8 0.0 3.5e-10 40.3 0.0 1.8 1 0 0 1 1 1 1 Reductase C-terminal NAD_binding_8 PF13450.6 AAZ34541.1 - 5.6e-08 32.9 4.3 1.3e-05 25.3 0.2 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 AAZ34541.1 - 1.5e-06 27.2 4.8 0.032 12.9 0.7 4.0 3 1 1 4 4 4 2 HI0933-like protein 2-Hacid_dh_C PF02826.19 AAZ34541.1 - 1.3e-05 24.7 0.4 3.5e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 AAZ34541.1 - 1.6e-05 24.1 4.1 0.036 13.2 0.0 2.5 2 1 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 AAZ34541.1 - 3.4e-05 23.3 1.4 0.13 11.5 1.1 3.8 3 1 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AAZ34541.1 - 4.1e-05 22.8 8.3 0.11 11.5 0.8 3.3 3 0 0 3 3 3 2 FAD binding domain Lycopene_cycl PF05834.12 AAZ34541.1 - 0.00056 19.1 7.8 0.048 12.7 0.9 3.2 2 1 1 3 3 3 2 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 AAZ34541.1 - 0.0006 19.2 0.0 0.0006 19.2 0.0 2.4 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain XdhC_C PF13478.6 AAZ34541.1 - 0.0015 19.0 0.2 0.019 15.5 0.0 2.4 2 0 0 2 2 2 1 XdhC Rossmann domain DAO PF01266.24 AAZ34541.1 - 0.013 15.1 14.2 0.033 13.8 1.7 3.5 2 2 2 4 4 4 0 FAD dependent oxidoreductase Amino_oxidase PF01593.24 AAZ34541.1 - 0.033 13.5 1.0 0.23 10.7 0.2 2.4 2 1 1 3 3 3 0 Flavin containing amine oxidoreductase TrkA_N PF02254.18 AAZ34541.1 - 0.1 12.8 0.2 6.9 7.0 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain 3HCDH_N PF02737.18 AAZ34541.1 - 0.29 11.0 0.1 0.29 11.0 0.1 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 AAZ34541.1 - 0.47 9.6 4.3 3.9 6.6 0.3 2.3 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 AAZ34541.1 - 1 9.3 8.4 5.5 7.0 0.1 3.8 3 1 1 4 4 4 0 FAD-NAD(P)-binding Glycos_transf_2 PF00535.26 AAZ34542.1 - 2.7e-23 82.6 0.0 4.1e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 AAZ34542.1 - 4e-10 40.0 11.5 4e-10 40.0 11.5 2.8 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 AAZ34542.1 - 1.6e-08 34.2 0.0 3.5e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 LysR_substrate PF03466.20 AAZ34543.1 - 3.7e-44 150.6 0.0 4.6e-44 150.3 0.0 1.1 1 0 0 1 1 1 1 LysR substrate binding domain SBP_bac_3 PF00497.20 AAZ34544.1 - 0.00024 20.6 0.0 0.00035 20.1 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 CheW PF01584.19 AAZ34545.1 - 2.3e-25 88.8 0.0 3e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 CheW-like domain Methyltransf_11 PF08241.12 AAZ34546.1 - 4.9e-06 27.1 0.0 1.4e-05 25.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAZ34546.1 - 0.001 19.7 0.0 0.0042 17.8 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAZ34546.1 - 0.0059 17.3 0.0 0.019 15.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_PK PF05891.12 AAZ34546.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Peripla_BP_2 PF01497.18 AAZ34547.1 - 2.9e-21 76.1 0.0 3.5e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein GDP_Man_Dehyd PF16363.5 AAZ34549.1 - 9e-99 331.0 0.0 1e-98 330.8 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 AAZ34549.1 - 2.3e-74 249.9 0.0 2.9e-74 249.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 AAZ34549.1 - 2.3e-15 56.5 0.0 5.8e-15 55.2 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 AAZ34549.1 - 7e-15 54.8 0.0 1.3e-14 53.9 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 AAZ34549.1 - 3.2e-14 52.7 0.0 5e-14 52.1 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 AAZ34549.1 - 5e-13 48.8 0.0 5.1e-11 42.2 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 AAZ34549.1 - 7.2e-07 28.9 0.1 0.012 15.1 0.0 2.5 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 AAZ34549.1 - 0.00012 22.0 0.1 0.00036 20.5 0.0 1.8 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 AAZ34549.1 - 0.0064 16.4 0.0 0.013 15.4 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 AAZ34549.1 - 0.13 12.5 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 AAZ34549.1 - 0.18 11.3 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family CoA_trans PF01144.23 AAZ34550.1 - 1.4e-23 83.5 0.0 1.7e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 Coenzyme A transferase His_Phos_1 PF00300.22 AAZ34551.1 - 1.4e-08 34.6 0.8 5.5e-07 29.5 0.1 2.4 2 1 1 3 3 3 2 Histidine phosphatase superfamily (branch 1) ExbD PF02472.16 AAZ34552.1 - 1.7e-26 92.9 0.4 2e-26 92.7 0.4 1.0 1 0 0 1 1 1 1 Biopolymer transport protein ExbD/TolR Nitroreductase PF00881.24 AAZ34553.1 - 1.5e-20 73.9 1.2 1.4e-17 64.3 1.2 2.1 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 AAZ34553.1 - 4e-07 29.8 0.0 0.00019 21.1 0.1 2.6 2 1 1 3 3 3 2 Putative TM nitroreductase DNA_pol3_alpha PF07733.12 AAZ34553.1 - 0.21 11.1 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial DNA polymerase III alpha NTPase domain YscJ_FliF PF01514.17 AAZ34554.1 - 2.8e-27 95.6 0.1 3.7e-27 95.3 0.1 1.1 1 0 0 1 1 1 1 Secretory protein of YscJ/FliF family DUF3180 PF11377.8 AAZ34554.1 - 0.048 13.8 0.1 0.13 12.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3180) HisG_C PF08029.11 AAZ34554.1 - 0.12 12.6 0.4 3.1 8.0 0.0 3.0 4 0 0 4 4 4 0 HisG, C-terminal domain PEP-CTERM PF07589.11 AAZ34554.1 - 0.47 10.6 2.5 1.3 9.2 2.5 1.9 1 0 0 1 1 1 0 PEP-CTERM motif SCO1-SenC PF02630.14 AAZ34555.1 - 4.3e-40 136.7 0.0 5.2e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 AAZ34555.1 - 4.9e-07 29.7 0.0 7.2e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 AAZ34555.1 - 0.081 13.3 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like DNA_topoisoIV PF00521.20 AAZ34556.1 - 6.7e-130 433.8 0.0 7.9e-130 433.6 0.0 1.0 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.13 AAZ34556.1 - 7e-11 41.4 0.2 6.1e-05 22.4 0.0 3.8 4 0 0 4 4 4 2 DNA gyrase C-terminal domain, beta-propeller ArsB PF02040.15 AAZ34557.1 - 5.3e-149 497.1 36.0 6.1e-149 496.9 36.0 1.0 1 0 0 1 1 1 1 Arsenical pump membrane protein CitMHS PF03600.16 AAZ34557.1 - 1.8e-26 93.1 45.7 1.8e-26 93.1 45.7 1.8 1 1 1 2 2 2 1 Citrate transporter MCPsignal PF00015.21 AAZ34558.1 - 4.4e-40 137.3 16.0 4.4e-40 137.3 16.0 2.7 1 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Uso1_p115_C PF04871.13 AAZ34558.1 - 0.83 10.0 13.7 0.77 10.1 1.6 3.0 3 0 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Laminin_II PF06009.12 AAZ34558.1 - 1.4 8.9 21.1 0.035 14.1 1.9 3.3 2 1 1 3 3 3 0 Laminin Domain II DUF1664 PF07889.12 AAZ34558.1 - 9 6.4 11.0 0.31 11.1 1.9 3.0 2 2 0 2 2 2 0 Protein of unknown function (DUF1664) P5CR_dimer PF14748.6 AAZ34559.1 - 1.1e-34 118.7 4.7 1.1e-34 118.7 4.7 2.1 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 AAZ34559.1 - 4.6e-22 78.4 2.3 4.6e-22 78.4 2.3 2.3 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 AAZ34559.1 - 1.4e-07 31.6 0.5 3.9e-07 30.2 0.1 1.9 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GFO_IDH_MocA PF01408.22 AAZ34559.1 - 1.4e-05 25.9 1.6 4.4e-05 24.3 0.2 2.3 3 0 0 3 3 3 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_2 PF03446.15 AAZ34559.1 - 5.2e-05 23.5 2.7 5.6e-05 23.4 1.1 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase OTCace PF00185.24 AAZ34559.1 - 0.00015 21.8 0.0 0.00026 21.1 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain PDH PF02153.17 AAZ34559.1 - 0.00037 19.6 0.3 0.0027 16.7 0.1 2.0 2 0 0 2 2 2 1 Prephenate dehydrogenase ApbA PF02558.16 AAZ34559.1 - 0.0041 16.8 2.1 0.011 15.3 2.1 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 AAZ34559.1 - 0.0043 17.1 0.3 0.013 15.5 0.1 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_C PF03720.15 AAZ34559.1 - 0.028 14.8 0.0 0.12 12.8 0.0 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Semialdhyde_dh PF01118.24 AAZ34559.1 - 0.12 12.8 0.8 0.3 11.5 0.4 2.0 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain 3HCDH_RFF PF18321.1 AAZ34559.1 - 0.14 12.6 4.1 1.2 9.6 0.2 3.4 3 0 0 3 3 3 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain Ribosomal_S11 PF00411.19 AAZ34559.1 - 0.8 10.1 4.8 2.1 8.8 0.2 3.0 2 1 0 3 3 3 0 Ribosomal protein S11 LysR_substrate PF03466.20 AAZ34561.1 - 3e-28 98.6 2.4 3e-28 98.6 2.4 1.8 1 1 1 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ34561.1 - 1.8e-17 63.0 1.4 5.6e-17 61.4 1.4 1.9 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_20 PF12840.7 AAZ34561.1 - 0.23 11.5 1.7 0.34 11.0 0.0 2.2 3 0 0 3 3 3 0 Helix-turn-helix domain ADH_N PF08240.12 AAZ34562.1 - 1.2e-25 89.5 0.6 2.7e-25 88.4 0.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AAZ34562.1 - 1.4e-11 44.5 1.4 6.5e-11 42.3 1.4 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 AAZ34562.1 - 2.6e-10 40.0 0.3 4.3e-10 39.3 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Glu_dehyd_C PF16912.5 AAZ34562.1 - 1.5e-05 24.6 0.2 0.00085 18.9 0.1 2.1 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 AAZ34562.1 - 0.00078 18.8 0.1 0.0013 18.1 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 AAZ34562.1 - 0.013 14.3 0.5 0.018 13.8 0.5 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 AAZ34562.1 - 0.028 13.7 0.1 0.041 13.1 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 AAZ34562.1 - 0.11 11.8 0.3 0.19 11.1 0.1 1.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase TonB_C PF03544.14 AAZ34563.1 - 6.2e-15 55.4 0.0 1.5e-14 54.1 0.0 1.7 1 0 0 1 1 1 1 Gram-negative bacterial TonB protein C-terminal TonB_2 PF13103.6 AAZ34563.1 - 0.00014 22.1 0.0 0.00026 21.1 0.0 1.5 1 0 0 1 1 1 1 TonB C terminal DUF5325 PF17259.2 AAZ34563.1 - 0.16 11.8 0.2 0.27 11.2 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5325) UbiA PF01040.18 AAZ34564.1 - 2.8e-66 223.4 21.1 3.4e-66 223.1 21.1 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF2178 PF09946.9 AAZ34564.1 - 0.13 12.5 0.2 0.13 12.5 0.2 2.5 3 1 0 3 3 3 0 Predicted membrane protein (DUF2178) Chalcone_3 PF16036.5 AAZ34565.1 - 1e-15 58.2 0.0 1.2e-15 58.0 0.0 1.1 1 0 0 1 1 1 1 Chalcone isomerase-like YbaJ PF10757.9 AAZ34565.1 - 0.041 14.4 0.0 0.06 13.9 0.0 1.2 1 0 0 1 1 1 0 Biofilm formation regulator YbaJ FtsJ PF01728.19 AAZ34566.1 - 7.6e-55 185.8 0.0 9.7e-55 185.4 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 AAZ34566.1 - 0.00011 22.0 0.0 0.0037 17.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAZ34566.1 - 0.025 15.3 0.1 0.47 11.2 0.1 2.5 1 1 0 1 1 1 0 Methyltransferase domain DUF1328 PF07043.13 AAZ34567.1 - 1.7e-17 63.3 21.3 2.2e-17 63.0 21.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1328) DUF2981 PF11200.8 AAZ34567.1 - 0.74 9.5 6.4 0.81 9.4 6.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) ATP-synt_A PF00119.20 AAZ34568.1 - 3.2e-56 190.6 20.9 3.9e-56 190.3 20.9 1.1 1 0 0 1 1 1 1 ATP synthase A chain Fer4_18 PF13746.6 AAZ34570.1 - 1.2e-46 157.6 7.9 2.1e-46 156.8 7.9 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain FixG_C PF11614.8 AAZ34570.1 - 3.7e-26 91.7 0.0 5.1e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 IG-like fold at C-terminal of FixG, putative oxidoreductase Fer4_7 PF12838.7 AAZ34570.1 - 3.6e-09 37.1 10.3 2.3e-05 24.9 1.7 3.2 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAZ34570.1 - 9.9e-08 32.0 10.9 5.2e-05 23.3 1.4 3.2 3 1 0 3 3 3 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAZ34570.1 - 1e-07 32.4 12.0 4.8e-05 23.8 1.3 2.9 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 AAZ34570.1 - 2e-07 31.3 9.2 5.4e-05 23.6 1.1 2.7 3 0 0 3 3 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAZ34570.1 - 2.3e-06 27.6 10.5 0.00016 21.7 1.9 2.7 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAZ34570.1 - 4.1e-06 27.6 7.2 0.00051 20.9 1.3 2.6 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_5 PF12801.7 AAZ34570.1 - 0.00016 21.5 8.7 0.00016 21.5 8.7 4.6 6 0 0 6 6 5 1 4Fe-4S binding domain Fer4_21 PF14697.6 AAZ34570.1 - 0.00041 20.4 12.6 0.14 12.3 5.2 3.2 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 AAZ34570.1 - 0.0021 17.8 24.1 0.0044 16.8 4.1 3.6 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_13 PF13370.6 AAZ34570.1 - 0.032 14.8 14.3 0.27 11.8 1.6 3.0 3 0 0 3 3 2 0 4Fe-4S single cluster domain of Ferredoxin I DUF1461 PF07314.11 AAZ34570.1 - 0.087 12.7 0.5 0.25 11.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1461) Fer4_22 PF17179.4 AAZ34570.1 - 0.091 13.6 6.3 1.5 9.7 0.7 2.8 2 0 0 2 2 2 0 4Fe-4S dicluster domain SpoIIM PF01944.17 AAZ34570.1 - 0.14 12.2 5.9 1.7 8.7 3.8 2.5 2 1 0 2 2 2 0 Stage II sporulation protein M Fer4_2 PF12797.7 AAZ34570.1 - 0.8 9.9 21.3 0.13 12.4 3.1 3.2 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_15 PF13459.6 AAZ34570.1 - 1.4 9.7 11.9 3.6 8.4 2.6 2.7 1 1 1 2 2 2 0 4Fe-4S single cluster domain DUF4823 PF16105.5 AAZ34571.1 - 3.5e-59 198.7 0.0 4.1e-59 198.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4823) LPAM_1 PF08139.12 AAZ34571.1 - 0.29 11.7 2.3 0.54 10.9 2.3 1.4 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site RepB PF07506.11 AAZ34572.1 - 2e-37 129.1 3.4 3e-37 128.5 3.4 1.2 1 0 0 1 1 1 1 RepB plasmid partitioning protein ParBc PF02195.18 AAZ34572.1 - 2e-11 44.0 0.0 4.3e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 ParB-like nuclease domain KorB PF08535.10 AAZ34572.1 - 0.013 15.5 0.2 0.096 12.7 0.1 2.6 1 1 0 2 2 2 0 KorB domain EAL PF00563.20 AAZ34573.1 - 2.6e-71 239.9 0.0 3.6e-71 239.4 0.0 1.2 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AAZ34573.1 - 7.2e-47 159.1 0.0 1.2e-46 158.3 0.0 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain MHYT PF03707.16 AAZ34573.1 - 7.3e-42 141.4 41.9 5.5e-19 68.1 4.0 5.2 5 0 0 5 5 5 4 Bacterial signalling protein N terminal repeat GGDEF_2 PF17853.1 AAZ34573.1 - 0.0094 16.2 0.1 0.08 13.2 0.0 2.6 2 0 0 2 2 2 1 GGDEF-like domain ParBc PF02195.18 AAZ34574.1 - 2.7e-29 101.3 0.7 6.4e-29 100.1 0.7 1.7 1 0 0 1 1 1 1 ParB-like nuclease domain HTH_ParB PF17762.1 AAZ34574.1 - 7.8e-17 60.8 1.3 7.8e-17 60.8 1.3 3.1 3 0 0 3 3 3 1 HTH domain found in ParB protein HTH_3 PF01381.22 AAZ34574.1 - 0.021 14.9 0.7 0.088 12.9 0.1 2.4 3 0 0 3 3 3 0 Helix-turn-helix HTH_Crp_2 PF13545.6 AAZ34574.1 - 0.028 14.4 1.5 0.071 13.1 0.1 2.4 3 0 0 3 3 3 0 Crp-like helix-turn-helix domain HTH_19 PF12844.7 AAZ34574.1 - 0.03 14.4 0.1 0.14 12.2 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain DUF1491 PF07372.12 AAZ34574.1 - 0.034 14.5 1.1 1.6 9.1 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1491) HTH_37 PF13744.6 AAZ34574.1 - 0.057 13.4 3.3 0.11 12.4 0.6 2.8 2 2 1 3 3 3 0 Helix-turn-helix domain RepB PF07506.11 AAZ34574.1 - 0.075 13.1 1.2 0.099 12.7 0.6 1.6 2 0 0 2 2 2 0 RepB plasmid partitioning protein HTH_23 PF13384.6 AAZ34574.1 - 0.11 12.3 0.4 0.37 10.6 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain SoPB_HTH PF18090.1 AAZ34574.1 - 0.12 12.5 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 Centromere-binding protein HTH domain HTH_31 PF13560.6 AAZ34574.1 - 0.16 12.4 0.1 0.16 12.4 0.1 3.3 4 1 0 4 4 4 0 Helix-turn-helix domain LysR_substrate PF03466.20 AAZ34575.1 - 6.4e-38 130.2 0.0 8.1e-38 129.9 0.0 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ34575.1 - 1.5e-18 66.5 0.0 8.5e-18 64.1 0.0 2.3 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 AAZ34575.1 - 0.043 13.7 0.4 0.21 11.5 0.1 2.1 2 0 0 2 2 2 0 MarR family BES1_N PF05687.13 AAZ34575.1 - 0.054 13.9 0.0 0.089 13.2 0.0 1.2 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal HTH_30 PF13556.6 AAZ34575.1 - 0.069 13.0 0.1 0.22 11.3 0.0 1.8 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_28 PF13518.6 AAZ34575.1 - 0.15 12.2 0.0 0.38 10.9 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain BPD_transp_1 PF00528.22 AAZ34576.1 - 1.6e-40 138.9 15.3 1.6e-40 138.9 15.3 1.8 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Ribonuc_L-PSP PF01042.21 AAZ34577.1 - 3.6e-42 143.2 0.1 4.1e-42 143.0 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP ATP-synt_I PF03899.15 AAZ34578.1 - 2.3e-22 79.2 13.3 2.3e-22 79.2 13.3 1.3 1 1 0 1 1 1 1 ATP synthase I chain Phage_holin_2_1 PF04971.12 AAZ34578.1 - 0.02 14.9 1.3 0.029 14.4 0.4 1.7 2 0 0 2 2 2 0 Bacteriophage P21 holin S DEAD PF00270.29 AAZ34579.1 - 2.9e-47 160.7 0.0 4.6e-46 156.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AAZ34579.1 - 2.6e-26 92.1 0.0 7.4e-26 90.7 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 AAZ34579.1 - 5.3e-07 29.8 0.0 8.7e-06 25.8 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 AAZ34579.1 - 0.00014 22.2 0.0 0.023 15.1 0.0 2.4 1 1 0 2 2 2 1 AAA domain ERCC3_RAD25_C PF16203.5 AAZ34579.1 - 0.034 13.3 0.0 0.055 12.7 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 AAZ34579.1 - 0.095 12.0 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 AAZ34579.1 - 0.22 11.8 1.9 1.2 9.4 0.4 2.6 2 1 0 2 2 2 0 AAA domain TonB_dep_Rec PF00593.24 AAZ34580.1 - 1.2e-63 216.6 16.1 1.2e-63 216.6 16.1 1.7 2 0 0 2 2 2 1 TonB dependent receptor Plug PF07715.15 AAZ34580.1 - 3.1e-17 63.1 0.2 7.5e-17 61.9 0.2 1.7 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain Phenol_MetA_deg PF13557.6 AAZ34580.1 - 0.31 11.0 9.2 0.071 13.1 0.5 3.1 3 0 0 3 3 3 0 Putative MetA-pathway of phenol degradation Acetyltransf_7 PF13508.7 AAZ34581.1 - 2.4e-10 40.7 0.0 3.6e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAZ34581.1 - 1.4e-09 38.0 0.0 2e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAZ34581.1 - 2.6e-08 34.1 0.0 3.3e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 AAZ34581.1 - 8.5e-07 29.0 0.0 1.4e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 AAZ34581.1 - 0.00097 19.1 0.0 0.0043 17.0 0.0 1.9 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_3 PF13302.7 AAZ34581.1 - 0.09 13.4 0.0 0.14 12.8 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain LolB PF03550.14 AAZ34582.1 - 9.6e-49 165.3 0.8 1.2e-48 165.0 0.8 1.1 1 0 0 1 1 1 1 Outer membrane lipoprotein LolB Hydrolase_4 PF12146.8 AAZ34583.1 - 1.1e-19 70.6 0.0 6.9e-16 58.2 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AAZ34583.1 - 2.3e-15 57.0 0.1 2e-13 50.6 0.2 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAZ34583.1 - 5e-11 43.6 6.3 6.9e-11 43.2 6.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 AAZ34583.1 - 2.7e-09 37.0 0.0 2.3e-06 27.4 0.1 2.1 1 1 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 AAZ34583.1 - 5.2e-07 29.4 0.0 2.1e-06 27.4 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 AAZ34583.1 - 8.2e-06 25.8 0.0 1.3e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.12 AAZ34583.1 - 1.2e-05 24.1 0.2 0.099 11.3 0.0 2.1 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) DUF3089 PF11288.8 AAZ34583.1 - 8.4e-05 22.2 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) FSH1 PF03959.13 AAZ34583.1 - 0.0036 17.0 0.0 0.011 15.4 0.0 1.7 2 0 0 2 2 2 1 Serine hydrolase (FSH1) BAAT_C PF08840.11 AAZ34583.1 - 0.013 15.4 0.0 0.038 13.9 0.0 1.6 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 AAZ34583.1 - 0.014 14.9 0.0 0.03 13.9 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family Esterase PF00756.20 AAZ34583.1 - 0.024 14.3 0.0 0.036 13.7 0.0 1.2 1 0 0 1 1 1 0 Putative esterase DUF1749 PF08538.10 AAZ34583.1 - 0.024 13.7 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) DUF3530 PF12048.8 AAZ34583.1 - 0.12 11.8 0.2 1.6 8.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) LIP PF03583.14 AAZ34583.1 - 0.18 11.1 0.0 14 4.9 0.0 2.2 2 0 0 2 2 2 0 Secretory lipase LPAM_1 PF08139.12 AAZ34583.1 - 0.34 11.5 1.7 0.77 10.4 1.7 1.6 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site OprD PF03573.13 AAZ34584.1 - 2.4e-128 428.6 15.1 2.7e-128 428.4 15.1 1.0 1 0 0 1 1 1 1 outer membrane porin, OprD family DUF2341 PF10102.9 AAZ34584.1 - 0.029 15.0 3.7 0.075 13.6 1.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2341) Ribosomal_TL5_C PF14693.6 AAZ34585.1 - 1.2e-27 96.0 0.3 2e-27 95.4 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein TL5, C-terminal domain Ribosomal_L25p PF01386.19 AAZ34585.1 - 8.2e-27 93.5 0.0 1.6e-26 92.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal L25p family CoA_binding PF02629.19 AAZ34586.1 - 3.9e-31 107.6 0.5 3.9e-31 107.6 0.5 2.2 3 1 0 3 3 3 1 CoA binding domain Ligase_CoA PF00549.19 AAZ34586.1 - 3.4e-22 78.9 0.3 5.2e-22 78.3 0.3 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 AAZ34586.1 - 3.1e-11 43.2 0.0 5.3e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 AAZ34586.1 - 0.0064 17.0 0.1 0.025 15.1 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain MCPsignal PF00015.21 AAZ34587.1 - 2.8e-45 154.2 26.8 3.4e-44 150.7 18.4 2.6 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.11 AAZ34587.1 - 4.4e-05 23.7 14.9 0.34 11.2 0.0 4.8 2 2 2 4 4 4 2 Bacterial protein of unknown function (DUF948) Prominin PF05478.11 AAZ34587.1 - 9.6e-05 20.6 1.1 0.00014 20.0 1.1 1.2 1 0 0 1 1 1 1 Prominin HAP1_N PF04849.13 AAZ34587.1 - 0.0058 15.9 0.4 0.0058 15.9 0.4 1.9 2 0 0 2 2 2 1 HAP1 N-terminal conserved region Spc7 PF08317.11 AAZ34587.1 - 0.014 14.3 3.1 1.2 7.9 0.7 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein BLOC1_2 PF10046.9 AAZ34587.1 - 0.031 14.6 7.5 0.63 10.4 0.3 4.1 2 2 3 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sec20 PF03908.13 AAZ34587.1 - 0.038 13.9 0.2 0.038 13.9 0.2 4.0 3 1 1 4 4 4 0 Sec20 Sec8_exocyst PF04048.14 AAZ34587.1 - 0.08 12.8 4.1 0.29 11.0 0.5 2.9 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain DUF812 PF05667.11 AAZ34587.1 - 0.098 11.5 8.4 0.05 12.5 6.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF1664 PF07889.12 AAZ34587.1 - 0.13 12.3 9.0 0.69 10.0 2.0 3.4 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) Arfaptin PF06456.13 AAZ34587.1 - 0.15 11.6 4.5 0.49 9.9 0.6 3.0 2 1 1 3 3 3 0 Arfaptin-like domain Pkip-1 PF06878.11 AAZ34587.1 - 0.16 12.0 0.1 0.36 10.9 0.1 1.7 1 0 0 1 1 1 0 Pkip-1 protein TetR_C_18 PF17923.1 AAZ34587.1 - 0.23 12.0 4.2 8.7 6.9 0.0 3.7 2 2 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain TACC_C PF05010.14 AAZ34587.1 - 0.24 11.2 5.5 0.51 10.1 0.1 3.1 3 1 0 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal TMPIT PF07851.13 AAZ34587.1 - 0.53 9.5 2.1 3.6 6.7 0.1 2.6 2 0 0 2 2 2 0 TMPIT-like protein DUF4200 PF13863.6 AAZ34587.1 - 0.55 10.6 4.5 0.82 10.1 0.1 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4200) Tropomyosin_1 PF12718.7 AAZ34587.1 - 0.76 9.9 3.9 4.8 7.3 0.1 3.0 2 1 0 2 2 2 0 Tropomyosin like BORCS6 PF10157.9 AAZ34587.1 - 0.87 9.8 4.7 0.88 9.8 0.5 2.7 2 2 1 3 3 3 0 BLOC-1-related complex sub-unit 6 V_ATPase_I PF01496.19 AAZ34587.1 - 0.92 7.3 3.0 1.6 6.5 1.1 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family MIP-T3_C PF17749.1 AAZ34587.1 - 0.93 9.4 5.5 0.4 10.6 0.5 2.7 3 0 0 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region DUF16 PF01519.16 AAZ34587.1 - 1.1 9.8 6.8 0.28 11.7 0.7 3.0 2 2 0 2 2 2 0 Protein of unknown function DUF16 GAT PF03127.14 AAZ34587.1 - 1.1 9.6 7.4 7.1 7.0 0.1 3.6 3 1 0 4 4 4 0 GAT domain NPV_P10 PF05531.12 AAZ34587.1 - 1.5 9.3 8.1 0.95 10.0 1.5 3.5 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Atg14 PF10186.9 AAZ34587.1 - 1.7 7.7 6.1 0.4 9.7 0.2 2.4 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2203 PF09969.9 AAZ34587.1 - 2.7 8.7 11.1 1.9 9.2 1.1 3.6 2 1 2 4 4 4 0 Uncharacterized conserved protein (DUF2203) TPR_MLP1_2 PF07926.12 AAZ34587.1 - 4.1 7.5 11.9 1.9 8.5 1.5 2.8 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4088 PF13317.6 AAZ34587.1 - 6.8 6.2 8.1 1.4 8.4 3.2 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF4088) DASH_Hsk3 PF08227.11 AAZ34587.1 - 7.7 7.0 7.9 2.2 8.7 0.3 3.5 4 0 0 4 4 2 0 DASH complex subunit Hsk3 like AAA_31 PF13614.6 AAZ34588.1 - 1.1e-37 129.6 0.0 1.7e-37 129.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 AAZ34588.1 - 2.9e-20 72.6 0.0 4.6e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 AAZ34588.1 - 4.9e-08 32.7 0.0 7.8e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase MipZ PF09140.11 AAZ34588.1 - 7e-08 32.1 0.1 1.2e-05 24.8 0.1 2.2 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 AAZ34588.1 - 1.7e-07 30.8 1.0 3.5e-06 26.4 0.0 3.0 3 1 0 3 3 3 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 AAZ34588.1 - 1.5e-06 27.9 0.2 5.9e-06 25.9 0.2 1.9 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 AAZ34588.1 - 4.1e-06 26.4 0.0 6.9e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CLP1_P PF16575.5 AAZ34588.1 - 0.033 14.0 0.1 0.18 11.6 0.0 2.2 1 1 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop GntP_permease PF02447.16 AAZ34589.1 - 1.1e-153 512.0 40.3 1.3e-153 511.8 40.3 1.0 1 0 0 1 1 1 1 GntP family permease CitMHS PF03600.16 AAZ34589.1 - 6.6e-19 68.2 48.7 1.1e-17 64.2 48.7 2.2 1 1 0 1 1 1 1 Citrate transporter DUF3007 PF11460.8 AAZ34589.1 - 0.17 12.1 0.3 0.17 12.1 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3007) T2SSF PF00482.23 AAZ34590.1 - 1.9e-66 221.7 3.0 4e-33 114.0 0.1 2.3 2 0 0 2 2 2 2 Type II secretion system (T2SS), protein F NADH5_C PF06455.11 AAZ34590.1 - 0.0047 16.5 7.0 0.55 9.8 0.2 2.3 2 0 0 2 2 2 2 NADH dehydrogenase subunit 5 C-terminus Cytochrom_C_2 PF01322.20 AAZ34590.1 - 0.25 12.2 0.9 31 5.5 0.1 2.8 3 0 0 3 3 3 0 Cytochrome C' DUF2897 PF11446.8 AAZ34590.1 - 3.1 7.7 9.8 6 6.8 1.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) Acetyltransf_7 PF13508.7 AAZ34591.1 - 2e-11 44.1 0.0 5.1e-11 42.9 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAZ34591.1 - 2.2e-11 44.0 0.0 2.8e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AAZ34591.1 - 5e-09 36.2 0.0 6.6e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GerE PF00196.19 AAZ34593.1 - 6.2e-09 35.3 0.0 8.7e-09 34.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AAZ34593.1 - 5.1e-06 26.1 0.0 1.2e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_10 PF04967.12 AAZ34593.1 - 0.007 16.1 0.0 0.017 14.9 0.0 1.8 1 1 0 1 1 1 1 HTH DNA binding domain HTH_38 PF13936.6 AAZ34593.1 - 0.0082 15.9 0.0 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 AAZ34593.1 - 0.011 15.6 0.9 0.019 14.9 0.0 1.8 2 0 0 2 2 2 0 MarR family HTH_24 PF13412.6 AAZ34593.1 - 0.019 14.5 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 AAZ34593.1 - 0.025 14.4 0.1 0.18 11.6 0.0 2.3 2 1 1 3 3 3 0 Homeodomain-like domain HTH_28 PF13518.6 AAZ34593.1 - 0.029 14.5 0.0 0.15 12.2 0.0 2.3 1 1 1 2 2 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 AAZ34593.1 - 0.037 13.5 0.0 0.091 12.3 0.0 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_20 PF12840.7 AAZ34593.1 - 0.038 14.1 0.1 0.13 12.4 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_IclR PF09339.10 AAZ34593.1 - 0.069 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 AAZ34593.1 - 0.13 11.7 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Sigma70_ECF PF07638.11 AAZ34593.1 - 0.5 10.2 3.4 0.71 9.7 0.0 2.4 2 1 1 3 3 3 0 ECF sigma factor Peptidase_M23 PF01551.22 AAZ34594.1 - 9.6e-32 109.1 0.5 2.9e-31 107.5 0.2 2.0 2 0 0 2 2 2 1 Peptidase family M23 LysM PF01476.20 AAZ34594.1 - 5.2e-14 52.0 0.0 1.4e-13 50.7 0.0 1.8 2 0 0 2 2 2 1 LysM domain Biotin_lipoyl_2 PF13533.6 AAZ34594.1 - 1.5e-06 28.0 0.0 8.4e-05 22.3 0.0 2.6 2 0 0 2 2 2 1 Biotin-lipoyl like RnfC_N PF13375.6 AAZ34594.1 - 0.024 14.6 1.9 0.12 12.4 0.0 2.6 3 0 0 3 3 3 0 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.22 AAZ34594.1 - 0.11 12.3 0.0 0.38 10.6 0.0 1.9 1 0 0 1 1 1 0 Biotin-requiring enzyme PAAR_motif PF05488.13 AAZ34595.1 - 8.3e-19 67.5 5.8 1.4e-18 66.8 2.2 2.9 2 1 1 3 3 3 1 PAAR motif DYW_deaminase PF14432.6 AAZ34595.1 - 8.6e-09 35.3 0.0 1.6e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 DYW family of nucleic acid deaminases DUF4150 PF13665.6 AAZ34595.1 - 0.00011 22.3 0.1 0.34 11.1 0.1 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4150) OTT_1508_deam PF14441.6 AAZ34595.1 - 0.012 15.6 0.1 0.029 14.4 0.1 1.6 1 0 0 1 1 1 0 OTT_1508-like deaminase Ku PF02735.16 AAZ34596.1 - 2.5e-33 115.5 0.1 3.6e-33 115.0 0.1 1.2 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Fer2 PF00111.27 AAZ34597.1 - 5.4e-13 48.7 0.4 1.2e-12 47.6 0.4 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.21 AAZ34597.1 - 4.3e-05 24.1 0.0 0.0011 19.5 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Fer2_4 PF13510.6 AAZ34597.1 - 0.014 15.4 0.0 0.089 12.9 0.0 2.2 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain NAD_binding_6 PF08030.12 AAZ34597.1 - 0.058 13.5 0.2 3.3 7.8 0.3 2.4 2 1 0 3 3 3 0 Ferric reductase NAD binding domain RicinB_lectin_2 PF14200.6 AAZ34597.1 - 0.22 12.3 0.0 0.49 11.2 0.0 1.5 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like DUF4113 PF13438.6 AAZ34598.1 - 0.025 14.7 0.1 0.041 14.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4113) JAMP PF05571.12 AAZ34598.1 - 0.13 11.9 0.1 0.15 11.6 0.1 1.1 1 0 0 1 1 1 0 JNK1/MAPK8-associated membrane protein Bac_luciferase PF00296.20 AAZ34599.1 - 5.5e-68 229.7 0.1 6.4e-68 229.5 0.1 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase MFS_1 PF07690.16 AAZ34600.1 - 1.8e-11 43.6 19.9 2e-11 43.4 19.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily GPI2 PF06432.11 AAZ34600.1 - 0.37 10.2 2.7 0.26 10.7 1.1 1.4 1 1 1 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase MCPsignal PF00015.21 AAZ34601.1 - 3.4e-42 144.2 32.5 2.1e-41 141.6 22.2 3.0 2 1 1 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain dCache_1 PF02743.18 AAZ34601.1 - 2.8e-34 119.0 0.5 2.8e-34 119.0 0.5 2.9 3 0 0 3 3 3 1 Cache domain Cache_3-Cache_2 PF17201.4 AAZ34601.1 - 2.1e-08 33.8 0.0 2.1e-08 33.8 0.0 2.7 3 0 0 3 3 3 1 Cache 3/Cache 2 fusion domain HAMP PF00672.25 AAZ34601.1 - 2.4e-06 27.8 0.0 2.4e-06 27.8 0.0 3.4 4 1 0 4 4 3 1 HAMP domain sCache_2 PF17200.4 AAZ34601.1 - 0.0023 17.8 0.2 0.016 15.0 0.0 2.5 2 0 0 2 2 2 1 Single Cache domain 2 Laminin_II PF06009.12 AAZ34601.1 - 0.0077 16.2 20.8 0.13 12.3 4.6 3.8 4 1 1 5 5 4 3 Laminin Domain II DUF1664 PF07889.12 AAZ34601.1 - 0.0084 16.1 16.0 0.35 10.9 1.4 4.5 2 2 2 4 4 4 2 Protein of unknown function (DUF1664) dCache_2 PF08269.11 AAZ34601.1 - 0.019 14.1 6.3 0.11 11.7 0.0 3.2 3 0 0 3 3 3 0 Cache domain DUF948 PF06103.11 AAZ34601.1 - 0.029 14.6 26.2 1.3 9.3 1.4 5.9 2 1 3 5 5 5 0 Bacterial protein of unknown function (DUF948) Serine_rich PF08824.10 AAZ34601.1 - 0.065 13.2 12.7 0.05 13.6 3.0 2.6 1 1 0 2 2 2 0 Serine rich protein interaction domain Aida_N PF08910.10 AAZ34601.1 - 0.11 12.8 4.5 1.7 9.1 0.1 3.1 2 2 1 3 3 3 0 Aida N-terminus VirionAssem_T7 PF11653.8 AAZ34601.1 - 0.5 10.9 3.0 5.7 7.5 0.1 3.1 3 0 0 3 3 2 0 Bacteriophage T7 virion assembly protein BLOC1_2 PF10046.9 AAZ34601.1 - 0.53 10.6 14.5 2 8.8 0.8 4.5 3 2 2 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF745 PF05335.13 AAZ34601.1 - 0.65 9.7 25.0 0.11 12.2 7.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF745) IFT57 PF10498.9 AAZ34601.1 - 0.98 8.3 8.9 3.1 6.7 1.6 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Fib_alpha PF08702.10 AAZ34601.1 - 1 9.6 9.0 8.1 6.6 1.3 2.9 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family CorA PF01544.18 AAZ34601.1 - 1.1 8.5 16.0 0.71 9.1 3.1 2.8 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein DASH_Duo1 PF08651.10 AAZ34601.1 - 1.2 9.0 8.4 3 7.7 0.5 3.9 3 1 1 4 4 4 0 DASH complex subunit Duo1 LXG PF04740.12 AAZ34601.1 - 2.1 8.0 11.3 0.31 10.7 3.8 2.7 1 1 1 2 2 2 0 LXG domain of WXG superfamily I_LWEQ PF01608.17 AAZ34601.1 - 2.4 8.4 19.0 0.18 12.0 9.6 3.0 2 1 1 3 3 3 0 I/LWEQ domain NPV_P10 PF05531.12 AAZ34601.1 - 2.4 8.7 8.0 1.7 9.2 0.8 3.6 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Cytochrome_B PF00033.19 AAZ34601.1 - 2.8 7.7 6.5 0.19 11.5 0.7 2.0 3 0 0 3 3 2 0 Cytochrome b/b6/petB WXG100 PF06013.12 AAZ34601.1 - 4.3 7.6 25.8 5.3 7.3 0.3 4.8 4 2 0 4 4 3 0 Proteins of 100 residues with WXG MafB PF06255.13 AAZ34601.1 - 8 5.8 10.7 2.5 7.4 6.0 2.2 1 1 1 2 2 2 0 Neisseria toxin MafB DUF3450 PF11932.8 AAZ34601.1 - 8.5 5.6 19.0 4.7 6.4 6.4 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) Methyltrans_SAM PF10672.9 AAZ34602.1 - 3.1e-137 456.5 0.0 3.5e-137 456.3 0.0 1.0 1 0 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase Cons_hypoth95 PF03602.15 AAZ34602.1 - 6.9e-09 35.6 0.0 1.1e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.6 AAZ34602.1 - 7.7e-05 22.5 0.0 0.00013 21.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AAZ34602.1 - 0.0027 17.3 0.0 0.0042 16.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 AAZ34602.1 - 0.0074 17.0 0.0 0.012 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 AAZ34602.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.16 AAZ34602.1 - 0.19 11.4 0.0 0.29 10.8 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein BPD_transp_1 PF00528.22 AAZ34604.1 - 3.2e-18 66.1 51.2 2.9e-13 50.0 19.6 4.1 2 2 1 3 3 3 2 Binding-protein-dependent transport system inner membrane component Toprim_4 PF13662.6 AAZ34605.1 - 3.8e-25 88.2 0.0 1.3e-24 86.5 0.0 1.8 2 0 0 2 2 2 1 Toprim domain RecR PF02132.15 AAZ34605.1 - 3.9e-15 55.1 0.4 7e-15 54.3 0.4 1.4 1 0 0 1 1 1 1 RecR protein Toprim PF01751.22 AAZ34605.1 - 9e-10 38.7 0.0 1.7e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Toprim domain HHH_5 PF14520.6 AAZ34605.1 - 0.0063 17.1 0.0 0.018 15.7 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain Toprim_2 PF13155.6 AAZ34605.1 - 0.02 15.3 0.0 0.046 14.2 0.0 1.6 2 0 0 2 2 2 0 Toprim-like HHH PF00633.23 AAZ34605.1 - 0.12 12.2 0.0 0.51 10.3 0.0 2.0 1 0 0 1 1 1 0 Helix-hairpin-helix motif HTH_1 PF00126.27 AAZ34606.1 - 8.6e-21 73.7 0.8 1.9e-20 72.5 0.7 1.7 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 AAZ34606.1 - 9e-21 74.2 0.0 1.4e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_5 PF01022.20 AAZ34606.1 - 0.0031 17.3 0.0 0.0059 16.5 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 AAZ34606.1 - 0.0034 17.4 0.2 0.0079 16.2 0.2 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.10 AAZ34606.1 - 0.013 15.3 0.9 0.028 14.2 0.5 1.8 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_24 PF13412.6 AAZ34606.1 - 0.031 13.8 0.1 0.063 12.9 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 AAZ34606.1 - 0.038 14.0 0.0 0.077 13.0 0.0 1.5 1 0 0 1 1 1 0 HTH domain MarR_2 PF12802.7 AAZ34606.1 - 0.047 13.6 2.5 0.17 11.8 0.2 2.6 3 0 0 3 3 3 0 MarR family DLH PF01738.18 AAZ34607.1 - 6.1e-54 182.9 0.1 7.4e-54 182.6 0.1 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 AAZ34607.1 - 8.1e-12 45.1 0.3 1.1e-05 25.0 0.0 2.3 1 1 1 2 2 2 2 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 AAZ34607.1 - 9.3e-09 35.3 0.6 5e-08 32.9 0.4 2.2 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.13 AAZ34607.1 - 3.2e-07 30.4 0.5 0.0018 18.2 0.0 2.7 2 1 1 3 3 3 2 alpha/beta hydrolase fold BAAT_C PF08840.11 AAZ34607.1 - 7.8e-07 29.2 0.9 0.00022 21.2 0.1 2.4 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 AAZ34607.1 - 0.0015 17.9 0.1 0.12 11.6 0.0 2.3 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 AAZ34607.1 - 0.0026 16.8 0.0 0.0034 16.5 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase GAF_2 PF13185.6 AAZ34607.1 - 0.0044 17.3 0.1 0.015 15.6 0.0 1.9 2 0 0 2 2 2 1 GAF domain AXE1 PF05448.12 AAZ34607.1 - 0.009 14.7 0.3 0.1 11.2 0.3 2.0 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Chlorophyllase2 PF12740.7 AAZ34607.1 - 0.042 12.8 0.0 0.058 12.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_2 PF02230.16 AAZ34607.1 - 0.048 13.5 0.0 0.069 12.9 0.0 1.1 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Esterase_phd PF10503.9 AAZ34607.1 - 0.05 13.1 0.7 0.36 10.3 0.1 2.4 2 1 1 3 3 3 0 Esterase PHB depolymerase E1-E2_ATPase PF00122.20 AAZ34608.1 - 3.7e-48 163.4 0.4 3.7e-48 163.4 0.4 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 AAZ34608.1 - 9.8e-21 75.0 0.0 1.7e-20 74.2 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Toxin_GhoT_OrtT PF10753.9 AAZ34608.1 - 0.17 12.1 1.5 0.26 11.5 0.1 2.0 2 0 0 2 2 2 0 Toxin GhoT_OrtT tRNA_U5-meth_tr PF05958.11 AAZ34609.1 - 3.7e-166 552.5 0.0 4.2e-166 552.3 0.0 1.0 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_25 PF13649.6 AAZ34609.1 - 2.7e-07 31.2 0.0 1.8e-06 28.6 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAZ34609.1 - 1.3e-06 28.3 0.0 2.6e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 AAZ34609.1 - 0.00015 21.3 0.0 0.00022 20.7 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_11 PF08241.12 AAZ34609.1 - 0.00037 21.1 0.0 0.0016 19.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 AAZ34609.1 - 0.0042 16.8 0.1 0.012 15.3 0.0 1.7 1 1 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 AAZ34609.1 - 0.0042 16.7 0.0 0.0071 15.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 AAZ34609.1 - 0.009 16.7 0.0 0.018 15.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 AAZ34609.1 - 0.022 13.9 0.0 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_15 PF09445.10 AAZ34609.1 - 0.026 14.1 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase DREV PF05219.12 AAZ34609.1 - 0.026 13.6 0.0 0.039 13.1 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Ubie_methyltran PF01209.18 AAZ34609.1 - 0.074 12.4 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PrmA PF06325.13 AAZ34609.1 - 0.18 11.1 0.1 0.27 10.6 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF3410 PF11890.8 AAZ34609.1 - 0.2 11.5 1.2 0.39 10.5 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3410) HDOD PF08668.12 AAZ34611.1 - 1.6e-10 40.8 2.0 5.4e-10 39.1 1.0 2.3 2 1 0 2 2 2 1 HDOD domain DpaA_N PF16924.5 AAZ34611.1 - 0.096 12.8 0.0 0.3 11.2 0.0 1.8 2 0 0 2 2 2 0 Dipicolinate synthase subunit A N-terminal domain DUF4329 PF14220.6 AAZ34612.1 - 2.1e-29 101.9 0.0 3.6e-28 97.9 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4329) Prok-JAB PF14464.6 AAZ34612.1 - 0.018 14.8 0.0 0.047 13.5 0.0 1.8 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain PsiE PF06146.12 AAZ34614.1 - 3.4e-15 56.2 0.0 4.3e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Phosphate-starvation-inducible E BPD_transp_1 PF00528.22 AAZ34615.1 - 2.7e-13 50.1 16.2 2.7e-13 50.1 16.2 1.5 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF4124 PF13511.6 AAZ34616.1 - 2.6e-15 56.5 7.6 1.4e-14 54.2 0.0 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4124) Acyl-CoA_dh_1 PF00441.24 AAZ34617.1 - 7.7e-53 178.7 2.3 1.2e-52 178.1 2.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 AAZ34617.1 - 2.5e-38 131.2 0.2 5.5e-38 130.1 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 AAZ34617.1 - 3.2e-27 95.4 1.3 6.2e-27 94.5 1.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 AAZ34617.1 - 4e-27 94.2 0.0 7.2e-27 93.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain LysR_substrate PF03466.20 AAZ34618.1 - 7.5e-23 81.0 4.9 1e-22 80.6 4.9 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ34618.1 - 6.2e-20 70.9 2.2 6.6e-20 70.8 0.7 1.9 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 AAZ34618.1 - 0.0011 18.8 0.2 0.0051 16.7 0.1 2.1 2 0 0 2 2 2 1 MarR family HTH_5 PF01022.20 AAZ34618.1 - 0.0045 16.8 0.1 0.0082 16.0 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_11 PF08279.12 AAZ34618.1 - 0.0092 15.9 0.1 0.031 14.2 0.0 1.9 2 0 0 2 2 2 1 HTH domain HTH_20 PF12840.7 AAZ34618.1 - 0.0097 16.0 0.1 0.028 14.5 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_30 PF13556.6 AAZ34618.1 - 0.012 15.4 0.0 0.042 13.7 0.0 2.0 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain P22_Cro PF14549.6 AAZ34618.1 - 0.028 14.3 0.1 0.06 13.2 0.1 1.5 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro HTH_IclR PF09339.10 AAZ34618.1 - 0.045 13.6 0.7 0.15 11.9 0.6 1.9 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_28 PF13518.6 AAZ34618.1 - 0.088 13.0 0.2 0.79 9.9 0.0 2.7 3 1 1 4 4 4 0 Helix-turn-helix domain HTH_24 PF13412.6 AAZ34618.1 - 0.099 12.2 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Sel_put PF04328.13 AAZ34619.1 - 3.5e-30 103.8 0.6 3.8e-30 103.7 0.6 1.0 1 0 0 1 1 1 1 Selenoprotein, putative HAD_2 PF13419.6 AAZ34620.1 - 1.4e-23 83.9 0.0 1.7e-23 83.6 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAZ34620.1 - 7.2e-18 65.6 0.2 5e-16 59.6 0.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AAZ34620.1 - 0.00021 21.3 0.0 0.00039 20.4 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 AAZ34620.1 - 0.002 18.5 0.1 0.0026 18.2 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AAZ34620.1 - 0.025 14.7 0.0 7.5 6.7 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase BPD_transp_2 PF02653.16 AAZ34621.1 - 1.5e-51 175.1 36.6 2e-51 174.8 36.6 1.1 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component HEAT_2 PF13646.6 AAZ34621.1 - 3.7e-07 30.4 15.2 0.00017 21.9 0.6 2.8 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.22 AAZ34621.1 - 0.77 10.2 0.0 0.77 10.2 0.0 4.1 4 1 1 5 5 5 0 HEAT repeat Aminotran_3 PF00202.21 AAZ34622.1 - 8.8e-79 265.0 0.0 1.2e-78 264.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 AAZ34622.1 - 1.5e-05 24.3 0.0 2.3e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II ACR_tran PF00873.19 AAZ34623.1 - 0 1284.0 18.5 0 1283.8 18.5 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AAZ34623.1 - 4.3e-10 39.0 29.4 2.6e-08 33.2 13.9 2.6 2 0 0 2 2 2 2 MMPL family SecD_SecF PF02355.16 AAZ34623.1 - 0.00025 20.5 25.9 0.034 13.5 17.6 2.4 2 0 0 2 2 2 2 Protein export membrane protein Patched PF02460.18 AAZ34623.1 - 0.21 9.6 17.1 0.4 8.7 17.1 1.4 1 0 0 1 1 1 0 Patched family Peptidase_M48_N PF16491.5 AAZ34623.1 - 1.9 8.4 7.5 1.9 8.4 0.2 2.9 2 0 0 2 2 2 0 CAAX prenyl protease N-terminal, five membrane helices RraA-like PF03737.15 AAZ34624.1 - 2.2e-32 112.3 0.7 2.7e-32 112.0 0.7 1.1 1 0 0 1 1 1 1 Aldolase/RraA Autotransporter PF03797.19 AAZ34625.1 - 1.1e-42 146.5 18.3 1.1e-42 146.5 18.3 2.0 2 0 0 2 2 2 1 Autotransporter beta-domain Lipase_GDSL PF00657.22 AAZ34625.1 - 7.7e-11 42.3 0.0 1.2e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 AAZ34625.1 - 7.5e-05 23.2 6.6 0.00053 20.4 6.6 2.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family OMP_b-brl PF13505.6 AAZ34625.1 - 0.00076 19.7 19.9 0.43 10.7 14.2 3.8 2 1 0 2 2 2 1 Outer membrane protein beta-barrel domain Acyltransferase PF01553.21 AAZ34626.1 - 2.6e-14 53.0 0.0 3.4e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 AAZ34626.1 - 0.06 13.5 0.3 0.21 11.7 0.0 2.1 3 0 0 3 3 3 0 Acyltransferase C-terminus QueF_N PF14819.6 AAZ34627.1 - 1.8e-46 157.0 0.0 5.2e-46 155.5 0.0 1.7 2 0 0 2 2 2 1 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term QueF PF14489.6 AAZ34627.1 - 6e-30 103.2 0.0 3.9e-24 84.6 0.0 2.2 2 0 0 2 2 2 2 QueF-like protein DHDPS PF00701.22 AAZ34628.1 - 7.3e-51 172.6 0.0 8.3e-51 172.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family CPBP PF02517.16 AAZ34629.1 - 1.9e-17 63.4 5.1 1.9e-17 63.4 5.1 2.7 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease Transp_cyt_pur PF02133.15 AAZ34630.1 - 1.3e-84 284.5 48.4 1.7e-84 284.2 48.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF3649 PF12365.8 AAZ34631.1 - 1.3e-06 28.0 11.8 1.3e-06 28.0 11.8 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3649) TusA PF01206.17 AAZ34632.1 - 1.5e-20 72.8 0.0 1.7e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 Sulfurtransferase TusA DUF1289 PF06945.13 AAZ34633.1 - 1.9e-15 56.4 3.3 2.3e-15 56.1 3.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1289) ADD_DNMT3 PF17980.1 AAZ34633.1 - 0.18 11.8 2.4 1.6 8.8 0.1 2.2 1 1 1 2 2 2 0 Cysteine rich ADD domain in DNMT3 Beta_helix PF13229.6 AAZ34634.1 - 3e-09 36.9 11.1 3e-09 36.9 11.1 2.3 2 1 1 3 3 3 2 Right handed beta helix region DUF4990 PF16380.5 AAZ34634.1 - 0.004 17.3 0.0 0.007 16.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function SLT_2 PF13406.6 AAZ34636.1 - 1.9e-111 372.0 0.4 2.3e-111 371.7 0.4 1.1 1 0 0 1 1 1 1 Transglycosylase SLT domain PG_binding_1 PF01471.18 AAZ34636.1 - 9.3e-13 48.2 0.6 2.5e-11 43.6 0.0 3.0 3 0 0 3 3 3 1 Putative peptidoglycan binding domain PG_binding_3 PF09374.10 AAZ34636.1 - 0.015 15.5 0.0 0.039 14.2 0.0 1.6 1 0 0 1 1 1 0 Predicted Peptidoglycan domain Glucosaminidase PF01832.20 AAZ34636.1 - 0.027 15.0 0.0 0.12 12.9 0.0 2.2 2 1 0 2 2 2 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase Metal_resist PF13801.6 AAZ34636.1 - 0.043 14.0 0.7 7.3 6.8 0.0 3.3 3 0 0 3 3 3 0 Heavy-metal resistance SLT PF01464.20 AAZ34636.1 - 0.052 13.2 0.0 0.61 9.8 0.0 2.5 2 1 0 2 2 2 0 Transglycosylase SLT domain GATase_3 PF07685.14 AAZ34637.1 - 8.4e-31 107.1 0.0 1.2e-30 106.6 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain CbiA PF01656.23 AAZ34637.1 - 4.8e-14 52.5 0.0 8.2e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.6 AAZ34637.1 - 4.1e-08 33.3 0.0 0.012 15.4 0.0 2.5 3 0 0 3 3 3 2 AAA domain DJ-1_PfpI PF01965.24 AAZ34637.1 - 0.039 13.8 0.0 0.066 13.0 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family AAA_30 PF13604.6 AAZ34637.1 - 0.079 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 AAZ34637.1 - 0.1 12.3 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain MobB PF03205.14 AAZ34637.1 - 0.15 12.0 0.0 4 7.3 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Ribosomal_S4 PF00163.19 AAZ34638.1 - 4.5e-31 107.6 1.4 7.1e-31 107.0 1.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 AAZ34638.1 - 1.1e-18 66.6 0.2 1.9e-18 65.9 0.2 1.4 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 AAZ34638.1 - 0.0019 18.0 0.2 0.0019 18.0 0.2 1.7 2 0 0 2 2 2 1 S4 domain PCB_OB PF17092.5 AAZ34638.1 - 0.15 12.8 0.9 0.2 12.4 0.2 1.5 2 0 0 2 2 2 0 Penicillin-binding protein OB-like domain DUF2177 PF09945.9 AAZ34639.1 - 1.4e-41 141.5 8.1 1.6e-41 141.3 8.1 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2177) DUF1761 PF08570.10 AAZ34639.1 - 0.3 11.3 6.1 0.43 10.8 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1761) ABC2_membrane_3 PF12698.7 AAZ34639.1 - 0.6 9.1 3.1 0.7 8.9 3.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein CCG PF02754.16 AAZ34641.1 - 2.9e-26 91.5 4.1 5.4e-13 49.0 0.2 3.2 3 0 0 3 3 3 2 Cysteine-rich domain Fer4_7 PF12838.7 AAZ34641.1 - 4.3e-13 49.6 4.7 9.7e-13 48.5 4.7 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 AAZ34641.1 - 1.9e-11 44.2 4.3 5.4e-11 42.8 4.3 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAZ34641.1 - 1.4e-10 41.6 4.5 3.7e-10 40.2 4.5 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 AAZ34641.1 - 4.5e-07 29.7 9.0 0.0032 17.5 2.1 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 AAZ34641.1 - 2.8e-06 28.1 3.4 6e-06 27.1 3.4 1.6 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 AAZ34641.1 - 3.3e-06 27.1 9.0 0.00018 21.6 10.5 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 AAZ34641.1 - 5.5e-06 26.0 6.6 0.014 15.2 0.5 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 AAZ34641.1 - 0.00011 22.1 13.5 0.031 14.4 3.3 2.8 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 AAZ34641.1 - 0.00034 20.7 10.6 0.02 15.1 11.6 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 AAZ34641.1 - 0.004 17.3 9.2 0.13 12.4 9.4 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 AAZ34641.1 - 0.0076 16.7 18.4 0.063 13.8 2.8 3.0 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_18 PF13746.6 AAZ34641.1 - 0.01 16.1 6.6 0.18 12.0 0.5 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_20 PF14691.6 AAZ34641.1 - 0.088 12.6 4.6 0.23 11.2 0.2 2.5 2 0 0 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_22 PF17179.4 AAZ34641.1 - 0.1 13.4 9.6 3.8 8.4 1.8 2.8 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 AAZ34641.1 - 1.1 9.9 9.7 4.4 7.9 1.1 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Glycos_transf_2 PF00535.26 AAZ34642.1 - 4.7e-22 78.6 0.0 6.2e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAZ34642.1 - 4.3e-05 23.5 0.0 5.9e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AAZ34642.1 - 0.0016 18.9 0.2 0.003 18.0 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 LAB_N PF07578.11 AAZ34642.1 - 0.0049 16.9 0.0 0.018 15.1 0.0 1.9 1 0 0 1 1 1 1 Lipid A Biosynthesis N-terminal domain Aminopep PF10023.9 AAZ34643.1 - 1.7e-135 451.6 0.1 1.9e-135 451.4 0.1 1.0 1 0 0 1 1 1 1 Putative aminopeptidase Peptidase_M1 PF01433.20 AAZ34643.1 - 0.088 12.4 0.0 0.15 11.6 0.0 1.4 1 1 0 1 1 1 0 Peptidase family M1 domain BcsB PF03170.13 AAZ34645.1 - 6.5e-11 41.3 0.0 4e-05 22.2 0.0 2.3 2 0 0 2 2 2 2 Bacterial cellulose synthase subunit Tn7_Tnp_TnsA_N PF08722.11 AAZ34646.1 - 1.1e-22 80.0 0.1 2.2e-22 79.0 0.1 1.5 1 0 0 1 1 1 1 TnsA endonuclease N terminal FliP PF00813.20 AAZ34647.1 - 6.6e-61 205.5 8.3 7.7e-61 205.3 8.3 1.0 1 0 0 1 1 1 1 FliP family ATG16 PF08614.11 AAZ34648.1 - 0.00097 19.4 9.1 0.0012 19.1 9.1 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) MscS_porin PF12795.7 AAZ34648.1 - 0.001 18.7 13.2 0.001 18.7 13.2 1.7 2 0 0 2 2 2 1 Mechanosensitive ion channel porin domain TMF_TATA_bd PF12325.8 AAZ34648.1 - 0.0054 16.9 3.4 0.0054 16.9 3.4 1.8 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding DUF4061 PF13270.6 AAZ34648.1 - 0.011 16.1 4.5 0.019 15.3 4.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) Spc7 PF08317.11 AAZ34648.1 - 0.047 12.6 6.4 0.073 11.9 6.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4140 PF13600.6 AAZ34648.1 - 0.056 13.9 8.0 0.025 15.0 3.9 1.9 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) FAM76 PF16046.5 AAZ34648.1 - 0.059 12.7 1.6 0.072 12.4 1.6 1.2 1 0 0 1 1 1 0 FAM76 protein DUF4407 PF14362.6 AAZ34648.1 - 0.062 12.6 9.0 0.086 12.2 9.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CDC48_2 PF02933.17 AAZ34648.1 - 0.085 12.6 0.4 0.17 11.7 0.4 1.4 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 Baculo_p24 PF05073.12 AAZ34648.1 - 0.19 11.5 1.7 0.35 10.6 1.7 1.3 1 0 0 1 1 1 0 Baculovirus P24 capsid protein DUF1690 PF07956.11 AAZ34648.1 - 0.19 12.1 6.4 0.12 12.8 3.0 1.9 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) Seryl_tRNA_N PF02403.22 AAZ34648.1 - 0.19 11.9 10.0 0.046 13.9 4.7 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ubiquitin PF00240.23 AAZ34648.1 - 0.26 11.1 2.3 0.57 10.0 2.3 1.5 1 0 0 1 1 1 0 Ubiquitin family FliJ PF02050.16 AAZ34648.1 - 0.43 10.8 15.6 0.22 11.8 10.7 2.1 1 1 1 2 2 2 0 Flagellar FliJ protein Sec8_exocyst PF04048.14 AAZ34648.1 - 0.59 10.0 8.9 1.6 8.6 2.4 2.8 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain TMPIT PF07851.13 AAZ34648.1 - 0.62 9.3 3.2 0.94 8.7 3.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein SlyX PF04102.12 AAZ34648.1 - 0.75 10.5 11.7 0.59 10.8 6.8 2.2 1 1 0 2 2 2 0 SlyX Snf7 PF03357.21 AAZ34648.1 - 0.95 9.0 11.6 0.24 11.0 8.9 1.4 2 0 0 2 2 2 0 Snf7 Sec2p PF06428.11 AAZ34648.1 - 1.1 9.2 11.8 0.71 9.9 6.3 2.3 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p FlxA PF14282.6 AAZ34648.1 - 1.3 9.1 28.5 0.14 12.2 22.3 2.3 2 1 0 2 2 2 0 FlxA-like protein Atg14 PF10186.9 AAZ34648.1 - 1.8 7.6 7.9 2.9 6.9 7.9 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 OmpH PF03938.14 AAZ34648.1 - 3.2 8.1 15.2 0.34 11.2 11.0 1.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF4094 PF13334.6 AAZ34648.1 - 9 6.8 8.3 24 5.4 3.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) CsiV PF10972.8 AAZ34649.1 - 3.5e-21 76.1 0.0 2.8e-13 50.2 0.0 3.3 1 1 1 2 2 2 2 Peptidoglycan-binding protein, CsiV DUF1942 PF09167.11 AAZ34649.1 - 0.054 13.5 0.0 0.091 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1942) HATPase_c PF02518.26 AAZ34650.1 - 8.8e-19 68.1 0.0 1.6e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 AAZ34650.1 - 2.4e-07 31.0 3.5 2.4e-07 31.0 3.5 2.2 2 0 0 2 2 2 1 HAMP domain HisKA PF00512.25 AAZ34650.1 - 0.0011 19.0 0.4 0.0011 19.0 0.4 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain DegS PF05384.11 AAZ34650.1 - 0.1 12.1 0.7 0.25 10.8 0.4 1.8 1 1 0 1 1 1 0 Sensor protein DegS UPF0184 PF03670.13 AAZ34650.1 - 0.48 10.8 1.4 2.4 8.6 0.2 2.5 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0184) Peptidase_U32 PF01136.19 AAZ34651.1 - 7.8e-71 237.9 0.0 1.1e-68 230.9 0.0 2.2 2 0 0 2 2 2 2 Peptidase family U32 DUF3656 PF12392.8 AAZ34651.1 - 1.8e-17 63.9 0.0 3.9e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 Collagenase Pap_E4 PF02711.14 AAZ34651.1 - 0.15 13.1 0.0 0.29 12.1 0.0 1.4 1 0 0 1 1 1 0 E4 protein GDPD PF03009.17 AAZ34651.1 - 0.16 11.7 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Ribosomal_L32p PF01783.23 AAZ34652.1 - 1.7e-20 73.0 0.4 1.8e-20 72.9 0.4 1.0 1 0 0 1 1 1 1 Ribosomal L32p protein family TadE PF07811.12 AAZ34653.1 - 9.9e-08 32.1 6.8 2.5e-07 30.9 6.8 1.7 1 0 0 1 1 1 1 TadE-like protein PAS_3 PF08447.12 AAZ34655.1 - 1.2e-43 147.3 1.4 7e-18 64.7 0.3 3.9 4 0 0 4 4 4 3 PAS fold PAS PF00989.25 AAZ34655.1 - 7.8e-23 80.6 0.0 3.3e-12 46.4 0.0 4.9 5 0 0 5 5 5 3 PAS fold PAS_9 PF13426.7 AAZ34655.1 - 4.4e-22 78.3 0.0 5.3e-12 45.9 0.0 4.6 4 0 0 4 4 4 3 PAS domain PAS_4 PF08448.10 AAZ34655.1 - 1.4e-18 67.1 6.5 1.6e-10 41.2 0.1 4.1 4 0 0 4 4 4 2 PAS fold PAS_8 PF13188.7 AAZ34655.1 - 2.6e-18 65.6 0.2 1e-06 28.6 0.0 4.2 4 0 0 4 4 3 3 PAS domain HATPase_c PF02518.26 AAZ34655.1 - 2.8e-17 63.3 0.0 4.9e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AAZ34655.1 - 2.6e-15 56.5 0.0 7.8e-15 55.0 0.0 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 AAZ34655.1 - 4.1e-07 29.9 4.1 6.9e-07 29.2 0.0 3.3 3 1 1 4 4 4 1 His Kinase A (phospho-acceptor) domain PAS_11 PF14598.6 AAZ34655.1 - 6.3e-07 29.5 0.0 0.13 12.4 0.0 3.4 3 0 0 3 3 3 3 PAS domain HPTransfase PF10090.9 AAZ34655.1 - 0.0018 18.1 0.1 0.011 15.5 0.0 2.4 2 0 0 2 2 2 1 Histidine phosphotransferase C-terminal domain HATPase_c_3 PF13589.6 AAZ34655.1 - 0.0029 17.4 0.0 0.0054 16.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Nup54 PF13874.6 AAZ34655.1 - 1.4 9.0 5.8 21 5.2 0.0 3.3 3 0 0 3 3 3 0 Nucleoporin complex subunit 54 OstA PF03968.14 AAZ34656.1 - 1.6e-26 92.7 6.2 2e-26 92.4 6.2 1.1 1 0 0 1 1 1 1 OstA-like protein LptC PF06835.13 AAZ34656.1 - 0.00059 19.5 1.8 0.15 11.7 0.3 2.1 1 1 1 2 2 2 2 Lipopolysaccharide-assembly, LptC-related YidD PF01809.18 AAZ34657.1 - 2e-29 101.2 0.8 2.3e-29 101.1 0.8 1.0 1 0 0 1 1 1 1 Putative membrane protein insertion efficiency factor Response_reg PF00072.24 AAZ34658.1 - 1.6e-27 95.9 0.0 2.6e-27 95.2 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AAZ34658.1 - 1.9e-18 65.7 0.4 3.3e-18 65.0 0.4 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Cadherin_2 PF08266.12 AAZ34658.1 - 0.00071 19.4 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 Cadherin-like HTH_40 PF14493.6 AAZ34658.1 - 0.005 17.3 0.1 0.0098 16.3 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 AAZ34658.1 - 0.0072 15.8 0.3 0.017 14.6 0.1 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_36 PF13730.6 AAZ34658.1 - 0.013 15.4 0.0 0.033 14.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 AAZ34658.1 - 0.017 14.8 0.1 0.035 13.8 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_28 PF13518.6 AAZ34658.1 - 0.045 13.9 0.1 0.34 11.1 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 AAZ34658.1 - 0.049 13.0 0.0 0.096 12.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Phage_terminase PF10668.9 AAZ34658.1 - 0.059 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Phage terminase small subunit HTH_38 PF13936.6 AAZ34658.1 - 0.086 12.6 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain FliL PF03748.14 AAZ34659.1 - 4.7e-20 72.1 0.2 6.3e-20 71.7 0.2 1.2 1 0 0 1 1 1 1 Flagellar basal body-associated protein FliL HrcA_DNA-bdg PF03444.15 AAZ34659.1 - 0.1 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Cpn10 PF00166.21 AAZ34660.1 - 3e-32 110.5 0.3 3.3e-32 110.4 0.3 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Metallophos PF00149.28 AAZ34661.1 - 4.1e-10 40.5 0.0 6.5e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AAZ34661.1 - 9.8e-08 32.4 0.1 6.5e-07 29.7 0.1 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SnoaL_2 PF12680.7 AAZ34662.1 - 1.1e-16 61.3 2.0 1.6e-16 60.8 2.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.6 AAZ34662.1 - 1.4e-08 35.0 0.3 2.1e-08 34.4 0.3 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 AAZ34662.1 - 6.9e-05 23.2 0.5 9.7e-05 22.7 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL PF07366.12 AAZ34662.1 - 0.00053 19.8 1.2 0.0016 18.3 1.2 1.7 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase AvrRpt-cleavage PF05627.11 AAZ34662.1 - 0.086 12.2 0.3 0.26 10.7 0.1 1.9 2 0 0 2 2 2 0 Cleavage site for pathogenic type III effector avirulence factor Avr DUF836 PF05768.14 AAZ34663.1 - 1e-16 61.1 0.0 1.1e-16 61.0 0.0 1.0 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 AAZ34663.1 - 0.01 16.1 0.1 0.013 15.7 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin TraF PF13728.6 AAZ34663.1 - 0.046 13.5 0.0 0.052 13.4 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein MS_channel PF00924.18 AAZ34664.1 - 6.1e-39 133.7 4.3 6.1e-39 133.7 4.3 2.5 2 0 0 2 2 2 1 Mechanosensitive ion channel DUF3772 PF12607.8 AAZ34664.1 - 7.1e-19 67.3 5.1 7.1e-19 67.3 5.1 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF3772) DUF4763 PF15960.5 AAZ34664.1 - 2.6 7.3 4.8 4 6.7 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) YlqD PF11068.8 AAZ34664.1 - 3.7 7.9 5.1 6.6 7.1 5.1 1.3 1 0 0 1 1 1 0 YlqD protein LPG_synthase_TM PF03706.13 AAZ34665.1 - 2.2e-45 155.5 45.9 2.7e-45 155.2 45.9 1.1 1 0 0 1 1 1 1 Lysylphosphatidylglycerol synthase TM region MoaE PF02391.17 AAZ34666.1 - 8.5e-37 125.9 0.0 9.7e-37 125.7 0.0 1.1 1 0 0 1 1 1 1 MoaE protein ABC_tran PF00005.27 AAZ34667.1 - 2.2e-38 131.8 0.0 3.5e-38 131.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter TOBE_2 PF08402.10 AAZ34667.1 - 4.8e-18 65.1 0.0 1.2e-17 63.9 0.0 1.7 1 0 0 1 1 1 1 TOBE domain AAA_21 PF13304.6 AAZ34667.1 - 5.1e-07 29.8 0.0 0.0062 16.4 0.0 2.5 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AAZ34667.1 - 0.00064 19.4 0.1 0.0013 18.5 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 AAZ34667.1 - 0.0016 17.9 0.6 0.036 13.5 0.2 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 AAZ34667.1 - 0.0029 17.5 0.1 0.0085 16.0 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_28 PF13521.6 AAZ34667.1 - 0.019 15.2 0.3 0.087 13.1 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 AAZ34667.1 - 0.031 14.7 0.1 0.049 14.0 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 AAZ34667.1 - 0.072 13.2 0.2 0.49 10.6 0.2 2.1 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AAZ34667.1 - 0.086 13.1 0.3 0.26 11.6 0.3 1.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AAZ34667.1 - 0.1 12.3 0.4 0.42 10.3 0.4 2.0 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 AAZ34667.1 - 0.12 11.6 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Peptidase_S3 PF00944.19 AAZ34667.1 - 0.12 12.2 0.0 0.3 10.9 0.0 1.6 2 0 0 2 2 2 0 Alphavirus core protein ABC_ATPase PF09818.9 AAZ34667.1 - 0.13 11.1 0.6 1.9 7.2 0.1 2.4 2 1 0 2 2 2 0 Predicted ATPase of the ABC class AAA_23 PF13476.6 AAZ34667.1 - 0.18 12.3 0.1 0.3 11.6 0.1 1.3 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 AAZ34667.1 - 0.23 10.9 0.2 3 7.3 0.2 2.1 2 0 0 2 2 2 0 Poxvirus A32 protein Peptidase_M10 PF00413.24 AAZ34668.1 - 2e-08 34.2 0.1 5.5e-08 32.8 0.1 1.7 2 0 0 2 2 2 1 Matrixin Astacin PF01400.24 AAZ34668.1 - 4.5e-05 23.1 5.8 0.0005 19.7 5.8 2.2 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Reprolysin_5 PF13688.6 AAZ34668.1 - 0.016 15.3 0.5 0.032 14.4 0.1 1.6 2 0 0 2 2 2 0 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 AAZ34668.1 - 0.059 13.3 0.1 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 AAZ34668.1 - 0.067 13.7 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 AAZ34668.1 - 0.09 12.4 0.9 0.12 12.0 0.0 1.6 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like 4HBT PF03061.22 AAZ34669.1 - 4.4e-15 55.8 0.4 7.4e-15 55.1 0.4 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 AAZ34669.1 - 0.029 14.6 0.2 0.036 14.3 0.2 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily CheB_methylest PF01339.17 AAZ34670.1 - 3.2e-51 173.4 0.0 3.7e-51 173.2 0.0 1.0 1 0 0 1 1 1 1 CheB methylesterase ComC PF03047.14 AAZ34671.1 - 0.0055 16.4 0.3 0.012 15.3 0.3 1.5 1 0 0 1 1 1 1 COMC family Bacteriocin_IIc PF10439.9 AAZ34671.1 - 0.018 15.2 13.2 0.032 14.3 13.2 1.5 1 1 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide MccV PF17508.2 AAZ34671.1 - 0.019 15.5 4.5 0.021 15.4 4.5 1.1 1 0 0 1 1 1 0 Microcin V bacteriocin Peptidase_Mx PF15887.5 AAZ34672.1 - 1.1e-104 348.9 0.2 1.4e-104 348.7 0.2 1.0 1 0 0 1 1 1 1 Putative zinc-binding metallo-peptidase zinc-ribbon_6 PF10005.9 AAZ34672.1 - 7e-28 97.2 0.5 1.2e-27 96.4 0.5 1.4 1 0 0 1 1 1 1 zinc-ribbon domain Peptidase_Mx1 PF15890.5 AAZ34672.1 - 0.0052 16.3 0.0 0.007 15.8 0.0 1.2 1 0 0 1 1 1 1 Putative zinc-binding metallo-peptidase LysR_substrate PF03466.20 AAZ34673.1 - 4.4e-35 120.9 1.4 5.8e-35 120.6 1.4 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ34673.1 - 1.3e-19 69.9 0.7 6.1e-19 67.7 0.1 2.2 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 AAZ34673.1 - 0.05 13.5 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 MarR family MarR PF01047.22 AAZ34673.1 - 0.054 13.4 0.0 0.19 11.7 0.0 1.9 1 0 0 1 1 1 0 MarR family HTH_24 PF13412.6 AAZ34673.1 - 0.086 12.4 0.2 0.31 10.6 0.0 2.1 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding P22_Cro PF14549.6 AAZ34673.1 - 0.17 11.7 0.1 0.41 10.5 0.1 1.5 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro PBP_like_2 PF12849.7 AAZ34673.1 - 0.21 11.2 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 PBP superfamily domain Glyoxalase PF00903.25 AAZ34674.1 - 5.8e-10 39.4 0.0 8.8e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 AAZ34674.1 - 2.7e-08 34.1 0.0 4.1e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 AAZ34674.1 - 0.0087 16.2 0.0 0.12 12.5 0.0 2.1 1 1 0 1 1 1 1 Glyoxalase-like domain Acetyltransf_10 PF13673.7 AAZ34674.1 - 0.1 12.5 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain COX1 PF00115.20 AAZ34675.1 - 5.5e-115 384.7 66.1 7.6e-115 384.2 66.1 1.2 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I LysR_substrate PF03466.20 AAZ34676.1 - 4.3e-31 107.9 0.0 6.4e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ34676.1 - 7.8e-17 61.0 0.2 1.5e-16 60.1 0.2 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_24 PF13412.6 AAZ34676.1 - 0.012 15.2 0.0 0.024 14.2 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 AAZ34676.1 - 0.012 15.4 0.3 0.085 12.7 0.0 2.2 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain MarR_2 PF12802.7 AAZ34676.1 - 0.024 14.5 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_Tnp_ISL3 PF13542.6 AAZ34676.1 - 0.094 12.1 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 MarR PF01047.22 AAZ34676.1 - 0.12 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 MarR family DUF2878 PF11086.8 AAZ34677.1 - 1.9e-44 151.6 28.2 2.2e-44 151.4 28.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2878) LacY_symp PF01306.19 AAZ34677.1 - 0.025 13.3 2.6 0.66 8.7 0.2 2.0 1 1 1 2 2 2 0 LacY proton/sugar symporter SCP2 PF02036.17 AAZ34678.1 - 1.8e-19 70.1 0.1 2e-19 69.9 0.1 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 AAZ34678.1 - 5e-09 36.5 0.1 5.9e-09 36.3 0.1 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal MarR_2 PF12802.7 AAZ34680.1 - 2.9e-10 39.9 0.5 2e-09 37.2 0.1 2.2 2 0 0 2 2 2 1 MarR family MarR PF01047.22 AAZ34680.1 - 1.3e-09 37.8 0.0 2.7e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 MarR family TFIIE_alpha PF02002.17 AAZ34680.1 - 0.0044 16.9 0.0 0.0072 16.2 0.0 1.5 1 1 0 1 1 1 1 TFIIE alpha subunit HTH_24 PF13412.6 AAZ34680.1 - 0.0093 15.5 0.0 0.021 14.4 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 AAZ34680.1 - 0.0098 15.7 0.2 0.093 12.5 0.0 2.3 2 0 0 2 2 2 1 IclR helix-turn-helix domain B-block_TFIIIC PF04182.12 AAZ34680.1 - 0.015 15.4 0.0 0.027 14.6 0.0 1.4 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC HTH_27 PF13463.6 AAZ34680.1 - 0.04 14.4 0.0 0.14 12.7 0.0 2.0 2 0 0 2 2 2 0 Winged helix DNA-binding domain HTH_37 PF13744.6 AAZ34680.1 - 0.07 13.1 0.2 0.17 11.9 0.2 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain DUF4174 PF13778.6 AAZ34682.1 - 4e-26 91.8 0.0 4.9e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4174) Sigma54_activat PF00158.26 AAZ34683.1 - 1.7e-66 223.1 0.1 2.4e-66 222.6 0.1 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain Response_reg PF00072.24 AAZ34683.1 - 3.7e-26 91.5 0.0 1e-25 90.1 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain Sigma54_activ_2 PF14532.6 AAZ34683.1 - 8.1e-24 84.3 0.1 3.8e-23 82.1 0.1 2.1 2 1 0 2 2 2 1 Sigma-54 interaction domain HTH_8 PF02954.19 AAZ34683.1 - 1.7e-10 40.5 0.5 5.7e-10 38.8 0.0 2.2 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family Mg_chelatase PF01078.21 AAZ34683.1 - 4.6e-06 26.2 0.1 0.00018 21.0 0.1 2.2 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 AAZ34683.1 - 2.2e-05 24.5 0.0 4.6e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) HTH_50 PF18024.1 AAZ34683.1 - 6.8e-05 22.4 0.0 0.00016 21.2 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain AAA_16 PF13191.6 AAZ34683.1 - 0.00044 20.7 2.4 0.00074 19.9 0.2 2.6 3 1 0 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 AAZ34683.1 - 0.00073 19.7 0.0 0.0012 19.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 AAZ34683.1 - 0.00091 19.7 0.0 0.002 18.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Phage_T7_tail PF03906.14 AAZ34684.1 - 2.6e-05 23.9 0.1 0.00045 19.9 0.0 2.9 2 1 0 2 2 2 1 Phage T7 tail fibre protein Pectate_lyase_3 PF12708.7 AAZ34684.1 - 2.7e-05 24.1 6.4 0.0074 16.1 0.0 3.3 2 1 1 3 3 3 2 Pectate lyase superfamily protein Beta_helix PF13229.6 AAZ34684.1 - 0.00038 20.3 12.3 0.0012 18.8 1.0 3.2 1 1 2 3 3 3 3 Right handed beta helix region GDC-P PF02347.16 AAZ34685.1 - 4.7e-194 645.1 0.0 5.3e-181 602.1 0.0 2.9 2 1 1 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 AAZ34685.1 - 1.6e-06 27.6 1.0 7.1e-06 25.5 0.2 2.0 2 0 0 2 2 2 1 Beta-eliminating lyase Aminotran_5 PF00266.19 AAZ34685.1 - 2.5e-06 26.7 0.1 0.0019 17.2 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Hpt PF01627.23 AAZ34686.1 - 1e-09 38.5 3.5 1.8e-09 37.7 3.5 1.4 1 0 0 1 1 1 1 Hpt domain Response_reg PF00072.24 AAZ34686.1 - 7e-09 35.9 0.0 1.6e-08 34.7 0.0 1.6 2 0 0 2 2 2 1 Response regulator receiver domain Zn_protease PF05618.11 AAZ34687.1 - 9.7e-44 148.6 0.0 1.1e-43 148.4 0.0 1.0 1 0 0 1 1 1 1 Putative ATP-dependant zinc protease HDV_ag PF01517.18 AAZ34687.1 - 0.079 12.7 0.1 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen PHA_gran_rgn PF09650.10 AAZ34688.1 - 2.1e-29 101.6 0.3 2.4e-29 101.4 0.3 1.1 1 0 0 1 1 1 1 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) EFG_IV PF03764.18 AAZ34688.1 - 0.0078 16.0 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor G, domain IV Rab_eff_C PF04698.12 AAZ34688.1 - 0.046 12.0 0.0 0.054 11.8 0.0 1.0 1 0 0 1 1 1 0 Rab effector MyRIP/melanophilin C-terminus Glucosaminidase PF01832.20 AAZ34689.1 - 1e-22 80.4 0.1 2.1e-22 79.4 0.1 1.5 1 0 0 1 1 1 1 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase Rod-binding PF10135.9 AAZ34689.1 - 2.2e-14 53.8 3.0 2.5e-14 53.6 0.5 2.6 2 0 0 2 2 2 1 Rod binding protein DUF4417 PF14386.6 AAZ34689.1 - 0.097 12.3 0.1 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4417) TonB_C PF03544.14 AAZ34690.1 - 7.3e-21 74.4 0.0 1.3e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 Gram-negative bacterial TonB protein C-terminal TonB_2 PF13103.6 AAZ34690.1 - 4.6e-05 23.6 0.0 4.6e-05 23.6 0.0 2.9 3 1 0 3 3 3 1 TonB C terminal TolA PF06519.11 AAZ34690.1 - 0.048 13.9 0.0 0.08 13.2 0.0 1.3 1 0 0 1 1 1 0 TolA C-terminal FixO PF02433.15 AAZ34691.1 - 1.2e-81 273.3 0.0 2.6e-77 259.1 0.0 2.0 1 1 1 2 2 2 2 Cytochrome C oxidase, mono-heme subunit/FixO Cytochrom_C PF00034.21 AAZ34691.1 - 9.4e-06 26.7 0.1 4.8e-05 24.4 0.1 2.0 1 1 0 1 1 1 1 Cytochrome c DUF2860 PF11059.8 AAZ34691.1 - 0.17 11.1 0.0 0.32 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2860) HhH-GPD PF00730.25 AAZ34692.1 - 1.1e-14 54.8 0.0 1.4e-14 54.4 0.0 1.1 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Ntox15 PF15604.6 AAZ34693.1 - 1.8e-28 99.6 0.0 3.4e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Novel toxin 15 CesT PF05932.13 AAZ34694.1 - 3.5e-06 27.1 0.0 4.1e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Tir chaperone protein (CesT) family NMT1_2 PF13379.6 AAZ34695.1 - 1.9e-91 306.2 0.0 2.4e-91 305.9 0.0 1.1 1 0 0 1 1 1 1 NMT1-like family NMT1 PF09084.11 AAZ34695.1 - 1.3e-05 25.2 0.0 0.00032 20.7 0.0 2.1 2 0 0 2 2 2 1 NMT1/THI5 like VirK PF06903.12 AAZ34696.1 - 6.9e-37 125.5 0.0 8.3e-37 125.2 0.0 1.1 1 0 0 1 1 1 1 VirK protein Methyltransf_23 PF13489.6 AAZ34697.1 - 1.2e-24 87.0 0.0 1.5e-24 86.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAZ34697.1 - 6.9e-22 77.9 0.0 1.1e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAZ34697.1 - 1.6e-18 67.2 0.0 2.3e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAZ34697.1 - 7.2e-17 62.0 0.0 1e-16 61.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAZ34697.1 - 7.3e-17 61.6 0.0 9.4e-17 61.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AAZ34697.1 - 9.4e-11 41.5 0.0 1.2e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 AAZ34697.1 - 2.4e-10 40.2 0.0 2.7e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 AAZ34697.1 - 7.9e-09 35.3 0.0 1.1e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 AAZ34697.1 - 1.8e-07 31.0 0.0 2.3e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 AAZ34697.1 - 1.4e-06 27.9 0.0 2.3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain TPMT PF05724.11 AAZ34697.1 - 1.3e-05 25.0 0.0 2.6e-05 24.0 0.0 1.5 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) DREV PF05219.12 AAZ34697.1 - 2.1e-05 23.7 0.0 2.9e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase MetW PF07021.12 AAZ34697.1 - 0.00013 21.6 0.0 0.00022 20.9 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.11 AAZ34697.1 - 0.00015 20.8 0.0 0.0002 20.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) TehB PF03848.14 AAZ34697.1 - 0.00026 20.4 0.0 0.00035 20.0 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 AAZ34697.1 - 0.0075 16.3 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 AAZ34697.1 - 0.052 13.5 0.0 0.088 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PilZ PF07238.14 AAZ34698.1 - 1.5e-06 28.5 0.0 1.6e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 PilZ domain RadC PF04002.15 AAZ34699.1 - 2.4e-45 153.4 0.1 3.5e-45 152.9 0.1 1.2 1 0 0 1 1 1 1 RadC-like JAB domain Prok-JAB PF14464.6 AAZ34699.1 - 0.002 17.9 0.3 0.0034 17.1 0.3 1.5 1 1 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF2316 PF10078.9 AAZ34699.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) TrkA_TMD PF18613.1 AAZ34699.1 - 0.34 10.4 1.5 0.81 9.2 1.5 1.6 1 0 0 1 1 1 0 Tyrosine kinase receptor A trans-membrane domain LysR_substrate PF03466.20 AAZ34700.1 - 5.3e-20 71.7 0.2 7.1e-20 71.3 0.2 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ34700.1 - 1.3e-16 60.3 0.6 2.7e-16 59.2 0.6 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family BPD_transp_1 PF00528.22 AAZ34701.1 - 1e-22 80.8 35.5 4.1e-16 59.3 14.1 3.8 2 2 1 3 3 3 2 Binding-protein-dependent transport system inner membrane component DUF4632 PF15451.6 AAZ34701.1 - 0.13 12.4 2.2 1.7 8.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) Glycos_transf_2 PF00535.26 AAZ34703.1 - 2.3e-13 50.3 0.0 3.8e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAZ34703.1 - 1.6e-12 47.8 0.0 2.1e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 AAZ34703.1 - 5e-07 29.3 0.0 7.9e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 AAZ34703.1 - 4.4e-06 26.7 0.0 6.1e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family group 2 DUF1534 PF07551.11 AAZ34704.1 - 1.7e-101 331.8 52.0 2.7e-30 103.8 4.0 4.1 4 0 0 4 4 4 4 Protein of unknown function (DUF1534) ExbD PF02472.16 AAZ34705.1 - 1.3e-27 96.6 0.5 1.5e-27 96.3 0.5 1.0 1 0 0 1 1 1 1 Biopolymer transport protein ExbD/TolR EAL PF00563.20 AAZ34706.1 - 4.9e-68 229.2 0.6 2.2e-66 223.8 0.0 2.9 3 0 0 3 3 3 1 EAL domain GGDEF PF00990.21 AAZ34706.1 - 8.7e-49 165.4 0.0 1.9e-48 164.3 0.0 1.6 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain GAF_2 PF13185.6 AAZ34706.1 - 2.3e-22 79.8 0.1 1.8e-10 41.2 0.0 3.2 2 0 0 2 2 2 2 GAF domain GAF PF01590.26 AAZ34706.1 - 1.3e-13 51.7 0.0 4.6e-06 27.3 0.0 2.9 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 AAZ34706.1 - 2.1e-11 44.2 0.1 0.00032 21.1 0.1 2.9 2 1 0 2 2 2 2 GAF domain ATP-cone PF03477.16 AAZ34707.1 - 2.7e-13 50.3 0.1 3.9e-13 49.8 0.1 1.2 1 0 0 1 1 1 1 ATP cone domain Lar_restr_allev PF14354.6 AAZ34707.1 - 0.0012 19.2 0.1 0.0018 18.6 0.1 1.3 1 0 0 1 1 1 1 Restriction alleviation protein Lar BAG PF02179.16 AAZ34707.1 - 0.025 15.0 0.1 0.06 13.8 0.1 1.6 1 0 0 1 1 1 0 BAG domain Zn-ribbon_8 PF09723.10 AAZ34707.1 - 0.029 14.5 0.7 8.2 6.6 0.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain Myc-LZ PF02344.15 AAZ34707.1 - 0.067 13.3 3.1 0.071 13.2 0.3 2.3 2 0 0 2 2 2 0 Myc leucine zipper domain Zn_Tnp_IS1595 PF12760.7 AAZ34707.1 - 0.071 13.1 0.8 0.13 12.3 0.8 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.6 AAZ34707.1 - 0.16 11.4 0.4 0.88 9.1 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain Iso_dh PF00180.20 AAZ34708.1 - 4e-138 460.3 0.0 4.6e-138 460.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Catalase PF00199.19 AAZ34709.1 - 5.1e-163 542.6 0.1 6.1e-163 542.4 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 AAZ34709.1 - 7.4e-16 58.1 0.0 1.7e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive Transposase_mut PF00872.18 AAZ34710.1 - 5.8e-117 390.8 0.0 7.3e-117 390.4 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ34710.1 - 7.8e-05 23.0 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain DUF4844 PF16133.5 AAZ34710.1 - 0.23 12.0 0.0 0.55 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) NA37 PF04245.13 AAZ34711.1 - 1e-87 294.5 0.0 1.2e-87 294.3 0.0 1.0 1 0 0 1 1 1 1 37-kD nucleoid-associated bacterial protein ACT_6 PF13740.6 AAZ34712.1 - 1.5e-17 63.3 0.1 2.3e-11 43.5 0.0 2.5 2 1 0 2 2 2 2 ACT domain ACT PF01842.25 AAZ34712.1 - 4.8e-09 35.8 0.8 1.9e-05 24.3 0.1 3.0 3 0 0 3 3 3 2 ACT domain ACT_4 PF13291.6 AAZ34712.1 - 5.9e-09 36.4 0.0 0.00048 20.6 0.0 2.2 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 AAZ34712.1 - 0.033 14.0 0.8 0.34 10.7 0.0 2.8 4 0 0 4 4 4 0 ACT domain Erythro-docking PF09277.11 AAZ34712.1 - 2 8.4 4.4 5 7.1 0.0 2.7 3 0 0 3 3 3 0 Erythronolide synthase, docking AP_endonuc_2 PF01261.24 AAZ34713.1 - 3.4e-18 65.9 0.6 4.3e-18 65.5 0.6 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel BPD_transp_1 PF00528.22 AAZ34714.1 - 2.9e-39 134.7 11.2 2.9e-39 134.7 11.2 1.6 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component CDP-OH_P_transf PF01066.21 AAZ34714.1 - 6.1 7.7 6.5 1e+03 0.6 6.5 3.5 1 1 0 1 1 1 0 CDP-alcohol phosphatidyltransferase rve PF00665.26 AAZ34715.1 - 1.5e-26 92.9 0.0 2.9e-26 92.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain HTH_21 PF13276.6 AAZ34715.1 - 2.9e-18 65.8 0.4 1.1e-16 60.7 1.5 2.4 2 0 0 2 2 2 1 HTH-like domain rve_3 PF13683.6 AAZ34715.1 - 4.8e-09 35.9 0.0 9.3e-09 34.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_2 PF13333.6 AAZ34715.1 - 0.16 12.2 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain DnaJ_C PF01556.18 AAZ34716.1 - 6.5e-38 130.1 0.0 8.3e-38 129.8 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 AAZ34716.1 - 8.8e-24 83.4 4.3 1.8e-23 82.4 4.3 1.5 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 AAZ34716.1 - 0.1 12.5 0.2 0.34 10.9 0.1 1.9 1 1 1 2 2 2 0 A repeated domain in UCH-protein RNase_E_G PF10150.9 AAZ34718.1 - 1.1e-94 316.9 0.1 1.6e-94 316.3 0.1 1.3 1 0 0 1 1 1 1 Ribonuclease E/G family S1 PF00575.23 AAZ34718.1 - 4.7e-15 55.7 0.1 1.1e-14 54.6 0.1 1.6 1 0 0 1 1 1 1 S1 RNA binding domain TcdA_TcdB PF12919.7 AAZ34718.1 - 0.093 12.0 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain OEP PF02321.18 AAZ34719.1 - 8.9e-62 208.2 46.8 2.4e-32 112.3 15.9 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein AAA_31 PF13614.6 AAZ34719.1 - 0.027 14.4 2.5 0.91 9.4 0.0 3.0 2 1 0 3 3 3 0 AAA domain IDH PF03971.14 AAZ34720.1 - 0 1314.3 0.2 0 1314.1 0.2 1.0 1 0 0 1 1 1 1 Monomeric isocitrate dehydrogenase PLDc_2 PF13091.6 AAZ34721.1 - 5e-35 120.3 0.0 4.6e-20 71.9 0.0 2.4 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 AAZ34721.1 - 8.4e-10 38.4 1.6 3.5e-05 23.8 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_3 PF13918.6 AAZ34721.1 - 2.9e-07 30.3 0.0 4.3e-05 23.2 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain FAM83 PF07894.12 AAZ34721.1 - 0.00043 19.9 0.0 0.00063 19.4 0.0 1.2 1 0 0 1 1 1 1 FAM83 A-H peroxidase PF00141.23 AAZ34722.1 - 2.3e-88 295.7 0.0 9e-47 159.7 0.0 2.3 2 0 0 2 2 2 2 Peroxidase Lip_A_acyltrans PF03279.13 AAZ34723.1 - 8.5e-85 284.5 0.0 9.6e-85 284.3 0.0 1.0 1 0 0 1 1 1 1 Bacterial lipid A biosynthesis acyltransferase DUF3671 PF12420.8 AAZ34724.1 - 0.16 12.1 0.8 7.2 6.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function ThiS PF02597.20 AAZ34725.1 - 9e-22 77.5 0.0 1e-21 77.4 0.0 1.0 1 0 0 1 1 1 1 ThiS family NAD_binding_1 PF00175.21 AAZ34726.1 - 7.8e-09 36.2 0.0 1.2e-08 35.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 AAZ34726.1 - 3.6e-08 33.7 0.0 8.3e-08 32.5 0.0 1.6 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 AAZ34726.1 - 0.1 12.8 0.0 1.8 8.7 0.0 2.4 3 0 0 3 3 3 0 Ferric reductase NAD binding domain BPD_transp_1 PF00528.22 AAZ34727.1 - 2.7e-10 40.3 18.0 2.7e-10 40.3 18.0 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component Sarcolipin PF05366.11 AAZ34727.1 - 0.16 11.7 2.1 0.19 11.5 0.2 2.1 2 0 0 2 2 2 0 Sarcolipin TP_methylase PF00590.20 AAZ34728.1 - 3.6e-47 161.1 0.6 4.2e-47 160.9 0.6 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Radical_SAM PF04055.21 AAZ34728.1 - 0.00094 19.6 0.0 0.0015 19.0 0.0 1.5 1 1 0 1 1 1 1 Radical SAM superfamily SBP_bac_1 PF01547.25 AAZ34729.1 - 1.9e-52 179.2 4.6 2.8e-52 178.6 4.6 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 AAZ34729.1 - 3.4e-27 96.0 5.1 5e-27 95.4 5.1 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein NUDIX PF00293.28 AAZ34730.1 - 5.9e-26 91.1 0.2 7.1e-26 90.8 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.6 AAZ34730.1 - 0.037 13.6 0.0 0.048 13.2 0.0 1.2 1 0 0 1 1 1 0 Nucleotide hydrolase NUDIX_4 PF14815.6 AAZ34730.1 - 0.058 13.4 0.2 0.079 12.9 0.2 1.5 1 1 0 1 1 1 0 NUDIX domain MCPsignal PF00015.21 AAZ34731.1 - 1.4e-42 145.5 44.4 9.7e-31 106.9 10.1 5.5 2 2 3 5 5 5 4 Methyl-accepting chemotaxis protein (MCP) signalling domain 4HB_MCP_1 PF12729.7 AAZ34731.1 - 1.1e-31 109.8 2.5 1.1e-31 109.8 2.5 4.5 3 2 3 6 6 6 1 Four helix bundle sensory module for signal transduction HAMP PF00672.25 AAZ34731.1 - 1.9e-10 40.9 0.1 1.9e-10 40.9 0.1 3.6 5 1 0 5 5 4 1 HAMP domain TarH PF02203.15 AAZ34731.1 - 1.1e-09 38.4 9.3 1.1e-09 38.4 9.3 4.9 5 0 0 5 5 5 1 Tar ligand binding domain homologue Mur_ligase_C PF02875.21 AAZ34731.1 - 0.0048 17.1 0.4 0.039 14.2 0.1 2.5 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain Tweety PF04906.13 AAZ34731.1 - 0.36 9.4 12.1 0.057 12.1 1.7 3.0 3 0 0 3 3 3 0 Tweety LMBR1 PF04791.16 AAZ34731.1 - 1.4 7.8 7.0 6.1 5.6 7.0 2.0 1 1 0 1 1 1 0 LMBR1-like membrane protein IFT57 PF10498.9 AAZ34731.1 - 2.6 6.9 17.9 0.94 8.4 2.3 2.5 3 0 0 3 3 3 0 Intra-flagellar transport protein 57 DUF1664 PF07889.12 AAZ34731.1 - 3 7.9 16.3 1.5 8.9 2.7 3.5 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 AAZ34731.1 - 4.3 6.5 13.5 1.9 7.7 1.8 2.5 2 0 0 2 2 2 0 TMPIT-like protein Sec34 PF04136.15 AAZ34731.1 - 4.5 7.1 11.8 11 5.9 0.7 3.0 2 1 0 2 2 2 0 Sec34-like family Muted PF14942.6 AAZ34731.1 - 6 7.2 19.2 6 7.2 0.4 3.6 3 0 0 3 3 3 0 Organelle biogenesis, Muted-like protein DUF948 PF06103.11 AAZ34731.1 - 6.1 7.2 28.5 1.8 8.9 6.9 5.0 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF948) SKA1 PF07160.12 AAZ34731.1 - 9.2 6.0 14.7 12 5.6 2.9 2.5 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF726 PF05277.12 AAZ34732.1 - 1.4e-12 47.2 0.0 2.2e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) DUF900 PF05990.12 AAZ34732.1 - 2.5e-06 27.2 0.2 1.4e-05 24.8 0.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_6 PF12697.7 AAZ34732.1 - 0.012 16.2 3.4 0.03 14.9 3.4 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAZ34732.1 - 0.037 13.3 0.0 0.065 12.5 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AAZ34732.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 AAZ34732.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.5 2 0 0 2 2 2 0 PGAP1-like protein FBPase PF00316.20 AAZ34733.1 - 2.3e-59 200.1 0.0 3e-59 199.7 0.0 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Methyltransf_10 PF05971.12 AAZ34734.1 - 1.4e-134 448.1 0.0 1.6e-134 447.9 0.0 1.0 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 AAZ34734.1 - 1.6e-06 27.7 0.0 3.6e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.18 AAZ34734.1 - 0.0019 17.9 0.0 0.0033 17.1 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.6 AAZ34734.1 - 0.0071 16.1 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAZ34734.1 - 0.022 15.4 0.0 0.041 14.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 AAZ34734.1 - 0.043 13.2 0.1 0.098 12.0 0.0 1.5 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 AAZ34734.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 AAZ34734.1 - 0.14 12.9 0.0 0.28 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Aminotran_1_2 PF00155.21 AAZ34735.1 - 3.2e-25 89.1 0.0 4.3e-25 88.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II GntR PF00392.21 AAZ34735.1 - 7.6e-12 44.7 0.0 1.8e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Aminotran_MocR PF12897.7 AAZ34735.1 - 0.00012 21.0 0.0 0.00026 19.9 0.0 1.5 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase HTH_41 PF14502.6 AAZ34735.1 - 0.056 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Aminotran_5 PF00266.19 AAZ34735.1 - 0.11 11.5 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V YaeQ PF07152.12 AAZ34736.1 - 6.6e-61 204.9 0.0 8e-61 204.6 0.0 1.1 1 0 0 1 1 1 1 YaeQ protein DUF1659 PF07872.11 AAZ34736.1 - 0.15 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1659) TPR_1 PF00515.28 AAZ34737.1 - 2.7e-18 64.9 2.3 0.0016 18.2 0.1 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 AAZ34737.1 - 2.1e-17 61.8 11.6 0.00028 20.8 0.0 5.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 AAZ34737.1 - 4.3e-14 51.9 7.8 6.2e-06 25.8 0.1 4.7 2 1 2 4 4 4 4 TPR repeat TPR_16 PF13432.6 AAZ34737.1 - 4.4e-13 49.6 20.7 2.3e-09 37.7 7.0 3.7 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 AAZ34737.1 - 1.4e-12 48.0 15.5 2.9e-07 30.9 5.9 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 AAZ34737.1 - 1.3e-11 44.2 20.1 6.1e-05 23.5 2.4 5.3 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 AAZ34737.1 - 5.3e-11 42.1 8.3 0.0003 21.0 0.1 5.1 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 AAZ34737.1 - 3e-10 39.5 0.6 0.022 15.0 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 AAZ34737.1 - 3.8e-08 33.5 17.9 0.0016 18.7 5.4 3.9 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 AAZ34737.1 - 2.2e-07 30.4 13.0 0.041 13.9 0.3 5.4 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 AAZ34737.1 - 3.8e-06 27.2 17.1 0.015 15.9 0.8 5.9 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_20 PF14561.6 AAZ34737.1 - 2.8e-05 24.3 7.9 0.0054 17.0 0.5 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 AAZ34737.1 - 0.00036 20.6 3.5 0.00036 20.6 3.5 4.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 AAZ34737.1 - 0.00065 19.0 7.6 0.016 14.4 0.8 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 AAZ34737.1 - 0.00071 19.7 2.3 0.025 14.8 0.1 3.1 1 1 2 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TolB_N PF04052.13 AAZ34737.1 - 0.0037 17.4 0.2 0.38 11.0 0.0 2.3 2 0 0 2 2 2 1 TolB amino-terminal domain Coatomer_WDAD PF04053.14 AAZ34737.1 - 0.0077 15.3 2.3 1.6 7.7 0.1 2.2 1 1 1 2 2 2 2 Coatomer WD associated region Coatomer_E PF04733.14 AAZ34737.1 - 0.0082 15.6 0.1 0.86 9.0 0.0 2.1 1 1 1 2 2 2 1 Coatomer epsilon subunit DUF3703 PF12487.8 AAZ34737.1 - 0.066 13.0 0.9 0.34 10.8 0.2 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3703) PSD5 PF07637.11 AAZ34737.1 - 0.41 11.0 3.7 7.1 7.1 0.4 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1595) TPR_21 PF09976.9 AAZ34737.1 - 0.51 10.0 9.5 3.9 7.1 9.2 2.4 1 1 0 1 1 1 0 Tetratricopeptide repeat-like domain Wzy_C_2 PF11846.8 AAZ34737.1 - 7.2 6.5 6.2 21 4.9 1.2 2.9 1 1 2 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal DUF1206 PF06724.11 AAZ34738.1 - 1.1e-39 134.3 38.2 5.8e-19 67.9 6.9 3.1 3 0 0 3 3 3 3 Domain of Unknown Function (DUF1206) Fumarate_red_D PF02313.17 AAZ34738.1 - 0.0071 16.4 0.4 0.0071 16.4 0.4 2.3 3 1 1 4 4 4 1 Fumarate reductase subunit D YtpI PF14007.6 AAZ34738.1 - 0.35 11.0 0.1 0.35 11.0 0.1 3.3 4 0 0 4 4 4 0 YtpI-like protein Ribosomal_L6 PF00347.23 AAZ34739.1 - 3.6e-41 139.7 0.2 3.1e-19 69.4 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Transposase_mut PF00872.18 AAZ34740.1 - 2e-117 392.3 0.0 2.5e-117 392.0 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ34740.1 - 7.8e-05 23.0 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain HTH_3 PF01381.22 AAZ34741.1 - 1.3e-11 44.3 0.1 2.3e-11 43.6 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix Cupin_2 PF07883.11 AAZ34741.1 - 5.9e-11 41.9 0.0 8.6e-11 41.4 0.0 1.3 1 0 0 1 1 1 1 Cupin domain HTH_31 PF13560.6 AAZ34741.1 - 9.5e-09 35.5 0.0 1.5e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 AAZ34741.1 - 4.3e-08 33.5 0.1 6.8e-08 32.8 0.1 1.3 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_19 PF12844.7 AAZ34741.1 - 5.8e-07 29.4 0.0 8.7e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 AAZ34741.1 - 0.0001 22.2 0.5 0.00015 21.6 0.5 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 AAZ34741.1 - 0.00091 19.0 0.3 0.0016 18.2 0.3 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Cupin_3 PF05899.12 AAZ34741.1 - 0.014 15.1 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) AraC_binding PF02311.19 AAZ34741.1 - 0.047 13.6 0.5 0.12 12.2 0.1 1.9 2 0 0 2 2 2 0 AraC-like ligand binding domain Cupin_7 PF12973.7 AAZ34741.1 - 0.088 12.7 0.1 0.21 11.6 0.1 1.6 1 1 0 1 1 1 0 ChrR Cupin-like domain TonB_C PF03544.14 AAZ34742.1 - 1.6e-19 70.1 0.0 3.6e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 Gram-negative bacterial TonB protein C-terminal TonB_2 PF13103.6 AAZ34742.1 - 2e-11 44.0 0.0 2e-11 44.0 0.0 2.8 3 1 0 3 3 3 1 TonB C terminal TolA PF06519.11 AAZ34742.1 - 0.025 14.7 0.0 0.06 13.6 0.0 1.6 1 0 0 1 1 1 0 TolA C-terminal LysR_substrate PF03466.20 AAZ34743.1 - 3.7e-46 157.1 5.4 5e-46 156.7 5.4 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ34743.1 - 6.8e-20 70.8 1.3 1.8e-19 69.4 1.3 1.8 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR PF01047.22 AAZ34743.1 - 0.062 13.2 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 MarR family FAST_1 PF06743.15 AAZ34743.1 - 0.07 13.1 0.1 0.17 11.8 0.0 1.7 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 HTH_24 PF13412.6 AAZ34743.1 - 0.099 12.2 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding XdhC_C PF13478.6 AAZ34744.1 - 7.2e-31 107.3 0.1 1.1e-30 106.8 0.1 1.3 1 0 0 1 1 1 1 XdhC Rossmann domain XdhC_CoxI PF02625.16 AAZ34744.1 - 1.9e-15 56.8 0.3 5.9e-15 55.2 0.3 1.9 1 0 0 1 1 1 1 XdhC and CoxI family DUF971 PF06155.12 AAZ34745.1 - 6.4e-25 87.6 0.0 9.8e-25 87.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF971) Beta-lactamase PF00144.24 AAZ34746.1 - 4.2e-59 200.4 1.4 5.6e-59 200.0 1.4 1.0 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 AAZ34746.1 - 0.007 15.8 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Response_reg PF00072.24 AAZ34747.1 - 3.7e-24 85.0 0.0 5.2e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAZ34747.1 - 1.1e-20 73.5 0.2 2.4e-20 72.4 0.2 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal BPD_transp_1 PF00528.22 AAZ34748.1 - 1.9e-39 135.3 11.6 1.9e-39 135.3 11.6 1.6 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Y2_Tnp PF04986.13 AAZ34750.1 - 5.4e-47 160.2 1.9 9.5e-47 159.4 1.9 1.4 1 0 0 1 1 1 1 Putative transposase Zn_Tnp_IS91 PF14319.6 AAZ34750.1 - 1.4e-22 79.6 7.3 2.7e-22 78.6 7.3 1.5 1 0 0 1 1 1 1 Transposase zinc-binding domain zf-B_box PF00643.24 AAZ34750.1 - 0.16 12.2 12.7 0.39 10.9 12.7 1.7 1 0 0 1 1 1 0 B-box zinc finger RseC_MucC PF04246.12 AAZ34752.1 - 0.0033 17.4 0.2 0.0036 17.2 0.2 1.0 1 0 0 1 1 1 1 Positive regulator of sigma(E), RseC/MucC DUF3040 PF11239.8 AAZ34752.1 - 0.024 14.9 0.0 0.028 14.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DUF973 PF06157.11 AAZ34752.1 - 0.027 13.6 0.1 0.029 13.4 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DUF2207 PF09972.9 AAZ34752.1 - 0.049 12.4 0.0 0.05 12.4 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4131 PF13567.6 AAZ34752.1 - 0.076 12.7 1.9 0.085 12.5 1.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF3377 PF11857.8 AAZ34752.1 - 0.2 11.6 0.0 3.4 7.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) DUF5392 PF17370.2 AAZ34752.1 - 0.2 11.7 0.7 0.24 11.5 0.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5392) HD PF01966.22 AAZ34753.1 - 8.6e-08 32.4 0.0 2.2e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 HD domain HD_assoc PF13286.6 AAZ34753.1 - 0.004 17.7 0.1 0.012 16.2 0.1 1.8 1 0 0 1 1 1 1 Phosphohydrolase-associated domain Aldedh PF00171.22 AAZ34754.1 - 2.8e-163 543.7 0.1 3.1e-163 543.6 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family OmdA PF13376.6 AAZ34754.1 - 0.052 13.6 0.2 0.13 12.2 0.2 1.6 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated Arc PF03869.14 AAZ34755.1 - 4.4e-25 87.3 1.2 5.5e-25 87.0 0.2 1.6 2 0 0 2 2 2 1 Arc-like DNA binding domain HicB PF05534.12 AAZ34755.1 - 0.05 13.4 0.0 0.083 12.8 0.0 1.4 1 0 0 1 1 1 0 HicB family DUF438 PF04282.13 AAZ34755.1 - 0.07 13.1 0.1 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF438) ParA PF10609.9 AAZ34756.1 - 1.7e-100 335.5 0.3 2.3e-100 335.1 0.3 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase FeS_assembly_P PF01883.19 AAZ34756.1 - 1.2e-15 57.4 0.0 3.6e-15 55.9 0.0 1.9 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein CbiA PF01656.23 AAZ34756.1 - 1.4e-15 57.4 0.0 2.8e-15 56.5 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 AAZ34756.1 - 1.1e-10 41.8 0.5 4.7e-08 33.1 0.2 2.2 2 0 0 2 2 2 2 AAA domain MipZ PF09140.11 AAZ34756.1 - 1.3e-08 34.4 0.1 4.8e-08 32.6 0.1 1.9 2 1 0 2 2 2 1 ATPase MipZ Fer4_NifH PF00142.18 AAZ34756.1 - 1e-07 31.7 0.4 0.00018 21.1 0.1 2.3 2 1 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 AAZ34756.1 - 6e-06 25.7 2.0 5e-05 22.6 0.2 2.6 2 1 1 3 3 3 1 Anion-transporting ATPase MeaB PF03308.16 AAZ34756.1 - 0.0007 18.7 0.1 0.0011 18.0 0.1 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB VirC1 PF07015.11 AAZ34756.1 - 0.00079 18.8 0.3 0.0069 15.7 0.1 2.1 2 0 0 2 2 2 1 VirC1 protein SRP54 PF00448.22 AAZ34756.1 - 0.0014 18.3 0.4 0.0062 16.2 0.1 2.0 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_26 PF13500.6 AAZ34756.1 - 0.0016 18.3 0.8 1.1 9.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 AAZ34756.1 - 0.0053 16.4 0.0 0.0086 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain CLP1_P PF16575.5 AAZ34756.1 - 0.02 14.7 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop FTHFS PF01268.19 AAZ34756.1 - 0.027 12.7 0.6 0.04 12.1 0.6 1.2 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase CBP_BcsQ PF06564.12 AAZ34756.1 - 0.05 13.1 1.0 0.17 11.3 0.2 1.9 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ DUF1974 PF09317.11 AAZ34757.1 - 4.5e-105 351.3 0.1 5.8e-105 350.9 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1974) Acyl-CoA_dh_N PF02771.16 AAZ34757.1 - 3.2e-19 69.6 0.1 7.2e-19 68.5 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 AAZ34757.1 - 6.1e-15 55.7 0.1 1.6e-14 54.3 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 AAZ34757.1 - 8.4e-09 35.5 0.0 1.8e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 AAZ34757.1 - 0.058 13.7 0.5 0.22 11.8 0.0 2.1 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain TetR_C_29 PF17938.1 AAZ34758.1 - 3.2e-46 156.3 0.1 4.5e-46 155.8 0.1 1.2 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 AAZ34758.1 - 1.1e-13 50.7 0.6 1.6e-13 50.2 0.6 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_9 PF14514.6 AAZ34758.1 - 0.026 14.6 0.0 0.044 13.9 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TetR_C_24 PF17932.1 AAZ34758.1 - 0.03 14.6 0.0 0.096 13.0 0.0 1.8 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DAO PF01266.24 AAZ34759.1 - 9.2e-72 242.5 0.4 1.1e-71 242.3 0.4 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 AAZ34759.1 - 4.3e-07 30.4 0.0 0.00018 22.0 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AAZ34759.1 - 9.3e-07 28.3 0.1 0.001 18.2 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 AAZ34759.1 - 1.7e-06 28.2 0.1 5.2e-05 23.4 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AAZ34759.1 - 3.3e-06 26.6 0.0 0.0015 17.8 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 AAZ34759.1 - 8.3e-06 25.5 0.0 2.8e-05 23.8 0.1 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 AAZ34759.1 - 3.7e-05 23.7 0.2 6.3e-05 22.9 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 AAZ34759.1 - 0.00048 19.7 0.0 0.00078 19.1 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 AAZ34759.1 - 0.00057 19.2 0.1 0.00085 18.7 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 AAZ34759.1 - 0.0011 18.3 0.3 0.0028 17.0 0.1 1.7 2 1 0 2 2 2 1 FAD binding domain XdhC_C PF13478.6 AAZ34759.1 - 0.005 17.3 0.0 0.011 16.3 0.0 1.6 1 0 0 1 1 1 1 XdhC Rossmann domain NAD_binding_7 PF13241.6 AAZ34759.1 - 0.0092 16.4 0.0 0.016 15.7 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Amino_oxidase PF01593.24 AAZ34759.1 - 0.014 14.7 0.0 0.74 9.0 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Thi4 PF01946.17 AAZ34759.1 - 0.018 14.3 0.0 0.054 12.7 0.1 1.7 2 0 0 2 2 2 0 Thi4 family NAD_binding_2 PF03446.15 AAZ34759.1 - 0.021 15.0 0.0 0.036 14.2 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ThiF PF00899.21 AAZ34759.1 - 0.027 13.8 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 ThiF family Sacchrp_dh_NADP PF03435.18 AAZ34759.1 - 0.031 14.5 0.0 0.073 13.3 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 AAZ34759.1 - 0.039 13.3 0.1 0.072 12.4 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 AAZ34759.1 - 0.06 13.4 0.1 0.19 11.8 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 AAZ34759.1 - 0.069 11.8 0.0 6.4 5.4 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 AAZ34759.1 - 0.13 11.4 0.2 0.23 10.5 0.2 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A TP6A_N PF04406.14 AAZ34759.1 - 0.16 12.0 0.2 0.38 10.8 0.2 1.6 1 1 0 1 1 1 0 Type IIB DNA topoisomerase FAD_oxidored PF12831.7 AAZ34759.1 - 0.16 11.3 1.1 1.2 8.4 0.7 2.2 2 1 0 2 2 2 0 FAD dependent oxidoreductase CbiA PF01656.23 AAZ34759.1 - 0.19 11.8 0.0 0.24 11.4 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Thioredoxin_4 PF13462.6 AAZ34760.1 - 2.8e-05 24.3 0.0 4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 AAZ34760.1 - 0.0022 17.8 0.0 0.11 12.3 0.0 2.1 1 1 0 1 1 1 1 DSBA-like thioredoxin domain YjbR PF04237.13 AAZ34761.1 - 5.3e-20 71.8 0.0 6.3e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 YjbR AbiEi_3 PF11459.8 AAZ34761.1 - 0.096 12.4 0.0 13 5.5 0.0 2.1 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system Phage_GPL PF05926.11 AAZ34762.1 - 1.2e-37 129.0 0.2 1.3e-37 128.8 0.2 1.0 1 0 0 1 1 1 1 Phage head completion protein (GPL) Aldolase_II PF00596.21 AAZ34763.1 - 5.7e-39 134.0 0.0 6.5e-39 133.8 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Xan_ur_permease PF00860.20 AAZ34764.1 - 5e-89 298.7 38.6 5e-89 298.7 38.6 1.3 1 1 0 1 1 1 1 Permease family SPW PF03779.14 AAZ34764.1 - 6.7 6.4 16.4 0.81 9.3 4.8 3.9 3 0 0 3 3 3 0 SPW repeat DNA_pol3_alpha PF07733.12 AAZ34765.1 - 2.3e-80 269.9 0.0 3.2e-80 269.5 0.0 1.2 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha NTPase domain DNA_pol3_finger PF17657.1 AAZ34765.1 - 2.2e-58 196.3 0.0 3.9e-58 195.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha subunit finger domain HHH_6 PF14579.6 AAZ34765.1 - 2.5e-20 72.5 0.1 7.8e-20 70.9 0.1 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif PHP PF02811.19 AAZ34765.1 - 1.3e-15 58.1 0.0 6.9e-15 55.7 0.0 2.0 2 0 0 2 2 2 1 PHP domain tRNA_anti-codon PF01336.25 AAZ34765.1 - 2.8e-08 33.6 0.1 5.2e-08 32.8 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF1560 PF07597.11 AAZ34765.1 - 0.086 12.9 0.2 0.77 9.8 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1560) tRNA_anti_2 PF13742.6 AAZ34765.1 - 0.19 11.9 0.0 0.46 10.7 0.0 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain PRTase_1 PF11202.8 AAZ34766.1 - 1.7e-90 302.6 0.0 2.3e-90 302.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase (PRTase) PELOTA_1 PF15608.6 AAZ34766.1 - 6.1e-28 96.5 0.2 1.3e-27 95.5 0.2 1.6 1 0 0 1 1 1 1 PELOTA RNA binding domain Radical_SAM PF04055.21 AAZ34767.1 - 1.1e-17 65.0 0.0 1.5e-17 64.5 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily HemN_C PF06969.16 AAZ34767.1 - 2.2e-12 46.9 0.4 4.5e-12 45.8 0.4 1.6 1 0 0 1 1 1 1 HemN C-terminal domain Fer4_12 PF13353.6 AAZ34767.1 - 0.058 13.7 0.0 0.092 13.0 0.0 1.2 1 0 0 1 1 1 0 4Fe-4S single cluster domain Fer4_14 PF13394.6 AAZ34767.1 - 0.21 11.7 0.0 0.34 11.1 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S single cluster domain zf-H2C2_5 PF13909.6 AAZ34767.1 - 0.55 10.0 1.7 1.1 9.0 1.7 1.5 1 0 0 1 1 1 0 C2H2-type zinc-finger domain G_glu_transpept PF01019.21 AAZ34768.1 - 1e-120 404.0 0.0 1.1e-120 403.8 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase ArgJ PF01960.18 AAZ34768.1 - 0.072 11.8 0.2 0.1 11.3 0.2 1.1 1 0 0 1 1 1 0 ArgJ family Peptidase_M75 PF09375.10 AAZ34769.1 - 6.8e-54 183.3 8.1 7.9e-54 183.1 8.1 1.0 1 0 0 1 1 1 1 Imelysin HTH_Tnp_Tc3_2 PF01498.18 AAZ34769.1 - 0.022 15.0 0.0 5 7.4 0.0 2.7 2 0 0 2 2 2 0 Transposase DUF4298 PF14131.6 AAZ34769.1 - 0.095 12.7 0.0 6.5 6.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) Shigella_OspC PF06128.11 AAZ34769.1 - 0.15 11.8 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Shigella flexneri OspC protein FAD_binding_3 PF01494.19 AAZ34770.1 - 4.3e-21 75.6 0.0 6.5e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 AAZ34770.1 - 2.4e-07 30.9 0.1 0.003 17.6 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 AAZ34770.1 - 2.1e-05 23.9 0.0 0.042 13.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AAZ34770.1 - 0.0003 20.5 3.3 0.00072 19.2 2.8 1.9 1 1 1 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 AAZ34770.1 - 0.0021 17.2 0.4 0.93 8.5 0.1 2.5 3 0 0 3 3 3 2 Lycopene cyclase protein HI0933_like PF03486.14 AAZ34770.1 - 0.031 13.0 0.1 0.15 10.7 0.0 2.0 3 0 0 3 3 3 0 HI0933-like protein SE PF08491.10 AAZ34770.1 - 0.054 12.5 0.0 0.084 11.9 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Trp_halogenase PF04820.14 AAZ34770.1 - 0.09 11.6 0.2 16 4.2 0.0 2.7 3 0 0 3 3 3 0 Tryptophan halogenase Kdo PF06293.14 AAZ34771.1 - 1.2e-62 210.9 0.0 1.5e-62 210.7 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Methylase_S PF01420.19 AAZ34772.1 - 2.6e-17 63.6 0.1 6.8e-09 36.2 0.0 2.4 2 0 0 2 2 2 2 Type I restriction modification DNA specificity domain GPS2_interact PF15784.5 AAZ34772.1 - 0.00055 20.3 1.9 0.24 11.8 0.1 2.4 2 0 0 2 2 2 2 G-protein pathway suppressor 2-interacting domain Osmo_CC PF08946.10 AAZ34772.1 - 3.5 8.0 6.9 11 6.4 4.3 2.5 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Transgly PF00912.22 AAZ34773.1 - 1.3e-63 213.6 0.0 2e-63 213.1 0.0 1.2 1 0 0 1 1 1 1 Transglycosylase Transpeptidase PF00905.22 AAZ34773.1 - 5.9e-30 104.5 0.0 2.5e-24 86.1 0.0 2.8 2 1 0 2 2 2 2 Penicillin binding protein transpeptidase domain PCB_OB PF17092.5 AAZ34773.1 - 3.5e-21 76.0 0.1 6.1e-21 75.3 0.1 1.4 1 0 0 1 1 1 1 Penicillin-binding protein OB-like domain DUF2384 PF09722.10 AAZ34774.1 - 1.9e-15 56.6 0.9 2.8e-15 56.1 0.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2384) HTH_8 PF02954.19 AAZ34774.1 - 0.0017 18.1 0.1 0.0039 16.9 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family HTH_24 PF13412.6 AAZ34774.1 - 0.063 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Phage_CI_repr PF07022.13 AAZ34774.1 - 0.066 13.3 0.0 0.26 11.4 0.0 2.0 2 1 1 3 3 3 0 Bacteriophage CI repressor helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 AAZ34774.1 - 0.091 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 DUF2164 PF09932.9 AAZ34776.1 - 1.1e-25 89.5 0.8 1.2e-25 89.3 0.8 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2164) SWC7 PF17330.2 AAZ34776.1 - 0.094 12.8 0.0 0.1 12.6 0.0 1.1 1 0 0 1 1 1 0 SWR1 chromatin-remodelling complex, sub-unit Swc7 F-box PF00646.33 AAZ34779.1 - 0.00014 21.7 0.1 0.00033 20.4 0.0 1.6 2 0 0 2 2 2 1 F-box domain DUF3106 PF11304.8 AAZ34779.1 - 0.058 13.9 1.1 0.11 13.0 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) RHS_repeat PF05593.14 AAZ34779.1 - 0.073 13.6 0.1 0.84 10.2 0.0 2.8 2 0 0 2 2 2 0 RHS Repeat F-box-like PF12937.7 AAZ34779.1 - 0.085 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 F-box-like INT_SG_DDX_CT_C PF15300.6 AAZ34779.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 INTS6/SAGE1/DDX26B/CT45 C-terminus FliJ PF02050.16 AAZ34779.1 - 0.1 12.8 6.2 0.7 10.1 3.3 2.3 1 1 1 2 2 2 0 Flagellar FliJ protein Cellulase PF00150.18 AAZ34780.1 - 4.1e-08 33.0 0.0 6.3e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) LysR_substrate PF03466.20 AAZ34781.1 - 8.8e-37 126.5 0.9 1.2e-36 126.1 0.9 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ34781.1 - 4.1e-22 77.9 1.8 6.8e-22 77.2 1.8 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_20 PF12840.7 AAZ34781.1 - 0.083 13.0 0.1 0.47 10.5 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain MarR_2 PF12802.7 AAZ34781.1 - 0.098 12.6 0.4 0.25 11.2 0.2 1.8 2 0 0 2 2 2 0 MarR family HTH_5 PF01022.20 AAZ34781.1 - 0.098 12.5 0.0 0.45 10.4 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family Fe-ADH PF00465.19 AAZ34782.1 - 4.8e-104 348.1 0.4 5.4e-104 347.9 0.4 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 AAZ34782.1 - 1.2e-15 57.9 2.1 2.7e-07 30.6 0.0 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase AA_kinase PF00696.28 AAZ34783.1 - 2.2e-19 70.0 0.0 3.3e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 Amino acid kinase family Acetyltransf_1 PF00583.25 AAZ34783.1 - 3.1e-09 37.1 0.1 7.5e-09 35.8 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAZ34783.1 - 7.2e-08 32.8 0.0 1.7e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAZ34783.1 - 4.1e-06 26.7 0.0 8.1e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MARVEL PF01284.23 AAZ34784.1 - 0.1 12.6 0.1 0.13 12.3 0.1 1.1 1 0 0 1 1 1 0 Membrane-associating domain AstA PF04958.12 AAZ34785.1 - 6.2e-135 449.1 0.0 6.9e-135 448.9 0.0 1.0 1 0 0 1 1 1 1 Arginine N-succinyltransferase beta subunit Glyco_tran_WecB PF03808.13 AAZ34785.1 - 0.16 11.9 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family DAO PF01266.24 AAZ34786.1 - 3.4e-34 119.0 2.4 4e-34 118.8 2.4 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AAZ34786.1 - 3.1e-07 29.9 1.3 4.9e-07 29.2 1.3 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 AAZ34786.1 - 0.00027 21.1 6.1 0.00081 19.6 4.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 AAZ34786.1 - 0.00028 20.9 0.7 0.0048 16.9 0.7 2.2 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 AAZ34786.1 - 0.00052 19.3 1.6 0.058 12.6 1.9 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AAZ34786.1 - 0.0007 18.9 2.4 0.0015 17.8 1.3 1.8 2 0 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.18 AAZ34786.1 - 0.00092 19.1 2.0 0.0015 18.5 2.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 AAZ34786.1 - 0.002 17.4 0.1 0.93 8.7 0.5 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AAZ34786.1 - 0.0042 15.8 4.9 1.2 7.7 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein ApbA PF02558.16 AAZ34786.1 - 0.033 13.8 3.5 0.067 12.8 3.5 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 AAZ34786.1 - 0.038 13.0 5.8 0.82 8.6 3.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_2 PF03446.15 AAZ34786.1 - 0.16 12.1 0.1 0.28 11.3 0.1 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase GIDA PF01134.22 AAZ34786.1 - 0.18 10.9 4.0 2.5 7.1 5.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.27 AAZ34786.1 - 0.18 12.4 1.6 0.66 10.6 1.6 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_M20 PF01546.28 AAZ34787.1 - 8.1e-17 61.6 0.0 1.5e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AAZ34787.1 - 2e-10 40.6 0.3 1.5e-06 28.1 0.0 3.8 2 2 0 2 2 2 2 Peptidase dimerisation domain Exo_endo_phos PF03372.23 AAZ34788.1 - 6.6e-20 71.6 0.0 1e-19 71.0 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 AAZ34788.1 - 0.01 15.7 0.0 0.39 10.6 0.0 2.3 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase PNP_UDP_1 PF01048.20 AAZ34789.1 - 5.1e-43 147.0 0.8 5.9e-43 146.8 0.8 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily NUDIX PF00293.28 AAZ34790.1 - 1.9e-17 63.5 0.0 3.2e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Nudix_hydro PF18290.1 AAZ34790.1 - 4.8e-14 52.1 0.0 8.6e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 Nudix hydrolase domain DUF4916 PF16262.5 AAZ34790.1 - 0.13 11.7 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4916) EVE PF01878.18 AAZ34791.1 - 4.3e-53 179.2 0.0 4.7e-53 179.1 0.0 1.0 1 0 0 1 1 1 1 EVE domain CBM32 PF18344.1 AAZ34791.1 - 0.26 11.2 0.5 0.42 10.5 0.5 1.3 1 0 0 1 1 1 0 Carbohydrate binding module family 32 Response_reg PF00072.24 AAZ34792.1 - 2.7e-19 69.4 0.5 2e-18 66.6 0.0 2.5 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 AAZ34792.1 - 3.4e-19 69.4 0.0 6.6e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAZ34792.1 - 1.6e-06 28.0 0.1 1.6e-06 28.0 0.1 2.8 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 AAZ34792.1 - 6.1e-05 23.2 1.4 0.00015 22.0 0.1 2.5 3 1 0 3 3 2 1 PAS fold PAS_9 PF13426.7 AAZ34792.1 - 0.024 14.9 0.0 0.12 12.7 0.0 2.2 2 0 0 2 2 2 0 PAS domain HATPase_c_3 PF13589.6 AAZ34792.1 - 0.025 14.4 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HPTransfase PF10090.9 AAZ34792.1 - 0.032 14.0 0.0 0.14 12.0 0.0 2.1 2 0 0 2 2 2 0 Histidine phosphotransferase C-terminal domain PAS_8 PF13188.7 AAZ34792.1 - 0.048 13.7 0.2 14 5.8 0.1 2.8 2 0 0 2 2 2 0 PAS domain PAS PF00989.25 AAZ34792.1 - 0.056 13.4 0.0 18 5.3 0.0 3.0 3 0 0 3 3 3 0 PAS fold PAS_10 PF13596.6 AAZ34792.1 - 0.072 13.7 0.1 5.3 7.7 0.0 3.0 3 0 0 3 3 3 0 PAS domain Sec34 PF04136.15 AAZ34792.1 - 0.22 11.4 3.3 33 4.3 0.0 3.0 3 0 0 3 3 3 0 Sec34-like family OmpH PF03938.14 AAZ34792.1 - 0.26 11.6 4.9 0.69 10.2 4.9 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HTH_31 PF13560.6 AAZ34793.1 - 4.6e-10 39.7 0.4 4.6e-10 39.7 0.4 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 AAZ34793.1 - 6.8e-08 32.5 0.1 1.2e-07 31.7 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 AAZ34793.1 - 1.1e-07 31.8 0.0 1.7e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 AAZ34793.1 - 8.6e-07 28.7 0.1 1.4e-06 28.1 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain PhdYeFM_antitox PF02604.19 AAZ34793.1 - 0.053 13.3 0.0 0.097 12.5 0.0 1.5 1 0 0 1 1 1 0 Antitoxin Phd_YefM, type II toxin-antitoxin system HTH_AraC PF00165.23 AAZ34793.1 - 0.13 12.4 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_24 PF13412.6 AAZ34793.1 - 0.14 11.7 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding AraC_N PF06719.13 AAZ34795.1 - 6.2e-35 120.0 0.0 8.6e-35 119.6 0.0 1.2 1 0 0 1 1 1 1 AraC-type transcriptional regulator N-terminus HTH_18 PF12833.7 AAZ34795.1 - 1.4e-21 76.5 1.4 2.1e-21 76.0 0.4 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAZ34795.1 - 1.5e-16 60.0 0.2 5.1e-07 29.6 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family YdiH PF15930.5 AAZ34795.1 - 0.0069 16.5 0.1 0.012 15.7 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function Lactamase_B_2 PF12706.7 AAZ34795.1 - 0.0077 15.8 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain ACR_tran PF00873.19 AAZ34796.1 - 0 1153.0 11.0 0 1152.8 11.0 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AAZ34796.1 - 3.2e-15 55.9 35.9 2e-10 40.2 12.7 2.3 2 0 0 2 2 2 2 MMPL family SecD_SecF PF02355.16 AAZ34796.1 - 0.0024 17.3 31.5 0.037 13.4 5.9 2.3 2 0 0 2 2 2 2 Protein export membrane protein Patched PF02460.18 AAZ34796.1 - 1.3 7.0 11.7 3.1 5.8 11.7 1.6 1 0 0 1 1 1 0 Patched family PmbA_TldD PF01523.16 AAZ34797.1 - 7.9e-59 199.8 0.1 1e-58 199.4 0.1 1.2 1 0 0 1 1 1 1 Putative modulator of DNA gyrase CxxCxxCC PF03692.15 AAZ34798.1 - 2.4e-11 44.2 4.8 2.6e-11 44.1 1.4 2.6 2 1 0 2 2 2 1 Putative zinc- or iron-chelating domain UMPH-1 PF05822.12 AAZ34798.1 - 0.021 14.4 0.0 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) GFRP PF06399.13 AAZ34798.1 - 0.16 11.9 0.1 20 5.1 0.0 2.5 1 1 1 3 3 3 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) OppC_N PF12911.7 AAZ34799.1 - 0.57 10.2 0.0 0.57 10.2 0.0 2.9 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C DUF1338 PF07063.13 AAZ34800.1 - 2.3e-120 401.7 0.1 2.7e-120 401.5 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) Peripla_BP_6 PF13458.6 AAZ34802.1 - 5.4e-65 220.3 12.4 6.5e-65 220.0 12.4 1.0 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 AAZ34802.1 - 5.6e-26 91.5 0.0 6.5e-26 91.3 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_5 PF13433.6 AAZ34802.1 - 2.3e-17 63.0 0.4 5.1e-17 61.9 0.4 1.6 1 1 0 1 1 1 1 Periplasmic binding protein domain NYN PF01936.18 AAZ34802.1 - 0.026 15.0 0.1 15 6.0 0.0 3.2 3 0 0 3 3 3 0 NYN domain ABC_sub_bind PF04392.12 AAZ34802.1 - 0.052 12.8 0.6 0.13 11.4 0.1 1.8 2 0 0 2 2 2 0 ABC transporter substrate binding protein LytR_C PF13399.6 AAZ34802.1 - 1.7 9.6 0.0 1.7 9.6 0.0 3.3 3 2 1 4 4 4 0 LytR cell envelope-related transcriptional attenuator Exonuc_V_gamma PF04257.14 AAZ34803.1 - 2.5e-276 918.9 0.0 3e-276 918.6 0.0 1.1 1 0 0 1 1 1 1 Exodeoxyribonuclease V, gamma subunit RecC_C PF17946.1 AAZ34803.1 - 1.3e-50 172.0 2.2 1.3e-50 172.0 2.2 2.2 2 0 0 2 2 2 1 RecC C-terminal domain GTP_cyclohydroI PF01227.22 AAZ34804.1 - 1.9e-75 252.2 0.1 2.1e-75 252.1 0.1 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I MAPKK1_Int PF08923.10 AAZ34804.1 - 0.0024 17.7 0.2 0.0031 17.3 0.2 1.3 1 0 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting QueF PF14489.6 AAZ34804.1 - 0.067 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 QueF-like protein FUR PF01475.19 AAZ34805.1 - 2.1e-42 144.0 0.1 2.7e-42 143.7 0.1 1.1 1 0 0 1 1 1 1 Ferric uptake regulator family PadR PF03551.14 AAZ34805.1 - 0.0088 16.0 0.0 0.02 14.9 0.0 1.6 2 0 0 2 2 2 1 Transcriptional regulator PadR-like family HTH_Tnp_Tc3_2 PF01498.18 AAZ34805.1 - 0.035 14.4 0.0 2.1 8.6 0.0 2.3 1 1 1 2 2 2 0 Transposase CDI PF02234.19 AAZ34805.1 - 0.037 14.2 0.2 0.22 11.8 0.0 2.3 3 0 0 3 3 3 0 Cyclin-dependent kinase inhibitor HTH_20 PF12840.7 AAZ34805.1 - 0.059 13.4 0.0 0.16 12.0 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_12 PF08461.10 AAZ34805.1 - 0.085 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain Bac_export_1 PF01311.20 AAZ34806.1 - 4.2e-67 226.1 35.7 4.8e-67 225.9 35.7 1.0 1 0 0 1 1 1 1 Bacterial export proteins, family 1 IMS PF00817.20 AAZ34807.1 - 2.2e-07 31.0 0.0 6.3e-07 29.5 0.0 1.7 2 0 0 2 2 2 1 impB/mucB/samB family ECH_2 PF16113.5 AAZ34808.1 - 1.3e-119 399.6 0.0 1.5e-119 399.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 AAZ34808.1 - 2.6e-31 108.9 0.0 3.2e-30 105.3 0.0 2.0 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase NADH-G_4Fe-4S_3 PF10588.9 AAZ34809.1 - 4.9e-15 54.8 0.7 1.1e-14 53.7 0.7 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Molybdop_Fe4S4 PF04879.16 AAZ34809.1 - 1.5e-11 44.1 0.3 4e-11 42.7 0.3 1.8 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain Fer2_4 PF13510.6 AAZ34809.1 - 2e-10 40.6 0.5 6.3e-10 39.0 0.1 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Molybdopterin PF00384.22 AAZ34809.1 - 8.5e-10 38.2 0.0 4e-08 32.7 0.0 2.4 2 1 0 2 2 2 1 Molybdopterin oxidoreductase Fer2 PF00111.27 AAZ34809.1 - 6.2e-09 35.7 0.2 6.2e-09 35.7 0.2 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 AAZ34809.1 - 0.044 13.5 1.9 0.1 12.4 0.7 2.1 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Peripla_BP_4 PF13407.6 AAZ34809.1 - 0.07 12.7 0.6 0.19 11.3 0.5 1.9 2 0 0 2 2 2 0 Periplasmic binding protein domain Fer4_6 PF12837.7 AAZ34809.1 - 0.72 10.0 8.8 0.27 11.4 0.9 3.4 3 0 0 3 3 3 0 4Fe-4S binding domain ExbD PF02472.16 AAZ34810.1 - 3.8e-29 101.5 0.5 4.2e-29 101.4 0.5 1.0 1 0 0 1 1 1 1 Biopolymer transport protein ExbD/TolR ChlI PF13541.6 AAZ34810.1 - 0.031 14.1 0.0 0.042 13.7 0.0 1.2 1 0 0 1 1 1 0 Subunit ChlI of Mg-chelatase Flg_bbr_C PF06429.13 AAZ34811.1 - 5.1e-25 87.4 3.3 8.1e-25 86.8 1.6 2.3 2 0 0 2 2 2 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 AAZ34811.1 - 3e-12 46.2 2.4 9.5e-12 44.6 2.4 2.0 1 0 0 1 1 1 1 Flagella basal body rod protein Sua5_yciO_yrdC PF01300.18 AAZ34812.1 - 6.2e-41 139.9 0.0 6.9e-41 139.7 0.0 1.0 1 0 0 1 1 1 1 Telomere recombination DegT_DnrJ_EryC1 PF01041.17 AAZ34813.1 - 3.6e-36 125.2 0.0 4e-36 125.1 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Flavin_Reduct PF01613.18 AAZ34814.1 - 2.7e-32 112.0 0.0 3.1e-32 111.8 0.0 1.0 1 0 0 1 1 1 1 Flavin reductase like domain ABC_tran PF00005.27 AAZ34815.1 - 4.2e-34 118.0 0.0 6.9e-34 117.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAZ34815.1 - 8.9e-13 48.7 0.5 5.6e-08 33.0 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAZ34815.1 - 8.2e-09 35.2 0.1 2.1e-08 33.9 0.1 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_13 PF13166.6 AAZ34815.1 - 1.3e-05 24.1 0.0 0.0021 16.8 0.0 2.1 1 1 1 2 2 2 2 AAA domain AAA_29 PF13555.6 AAZ34815.1 - 0.00061 19.5 0.1 0.0011 18.6 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_ATPase PF09818.9 AAZ34815.1 - 0.00084 18.3 0.0 0.51 9.1 0.0 2.2 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 AAZ34815.1 - 0.0021 18.5 0.9 0.006 17.0 0.9 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AAZ34815.1 - 0.0047 17.2 0.2 0.047 13.9 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 AAZ34815.1 - 0.0053 17.3 0.0 0.0096 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain G-alpha PF00503.20 AAZ34815.1 - 0.015 14.4 0.1 0.04 13.1 0.1 1.3 1 1 0 1 1 1 0 G-protein alpha subunit AAA_15 PF13175.6 AAZ34815.1 - 0.018 14.8 0.0 3.2 7.4 0.0 2.1 1 1 1 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 AAZ34815.1 - 0.018 14.9 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 AAZ34815.1 - 0.029 14.1 0.2 0.12 12.1 0.1 2.1 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 AAZ34815.1 - 0.046 13.9 0.1 0.41 10.9 0.1 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.22 AAZ34815.1 - 0.054 12.7 0.0 0.16 11.1 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain cobW PF02492.19 AAZ34815.1 - 0.055 13.1 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 AAZ34815.1 - 0.059 13.3 0.2 0.1 12.5 0.2 1.8 1 1 0 1 1 1 0 NACHT domain PRK PF00485.18 AAZ34815.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family DUF87 PF01935.17 AAZ34815.1 - 0.14 12.2 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain LexA_DNA_bind PF01726.16 AAZ34816.1 - 2.4e-30 104.1 0.0 3.6e-30 103.5 0.0 1.3 1 0 0 1 1 1 1 LexA DNA binding domain Peptidase_S24 PF00717.23 AAZ34816.1 - 1.1e-15 57.4 0.0 1.8e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like MarR_2 PF12802.7 AAZ34816.1 - 0.0005 19.9 0.0 0.0032 17.3 0.0 2.2 2 0 0 2 2 2 1 MarR family HTH_20 PF12840.7 AAZ34816.1 - 0.005 16.9 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 AAZ34816.1 - 0.02 14.9 0.0 0.049 13.6 0.0 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Rrf2 PF02082.20 AAZ34816.1 - 0.083 13.2 0.0 0.39 11.1 0.0 2.0 2 0 0 2 2 2 0 Transcriptional regulator HTH_36 PF13730.6 AAZ34816.1 - 0.15 12.0 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain AMP-binding PF00501.28 AAZ34817.1 - 3.5e-107 358.6 0.0 4.2e-107 358.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAZ34817.1 - 2.1e-19 70.2 3.1 2e-17 63.9 0.4 2.7 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.6 AAZ34817.1 - 0.0082 16.4 0.0 0.023 15.0 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Arabinose_bd PF12625.7 AAZ34818.1 - 7e-23 81.7 2.6 1.3e-22 80.8 2.6 1.4 1 0 0 1 1 1 1 Arabinose-binding domain of AraC transcription regulator, N-term HTH_18 PF12833.7 AAZ34818.1 - 2.5e-11 43.7 2.7 1.1e-10 41.7 0.2 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAZ34818.1 - 1.3e-09 37.9 0.0 0.00074 19.5 0.0 2.7 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Sigma70_r4_2 PF08281.12 AAZ34818.1 - 0.04 13.6 0.0 3.3 7.5 0.0 2.6 2 0 0 2 2 2 0 Sigma-70, region 4 Sec7 PF01369.20 AAZ34818.1 - 0.074 12.7 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 Sec7 domain RWP-RK PF02042.15 AAZ34818.1 - 0.083 12.9 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 RWP-RK domain DUF1281 PF06924.11 AAZ34818.1 - 0.091 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) SurA_N PF09312.11 AAZ34818.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 SurA N-terminal domain HTH_7 PF02796.15 AAZ34818.1 - 0.18 11.9 0.0 0.46 10.6 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase NadA PF02445.16 AAZ34819.1 - 3.4e-104 348.2 0.1 4e-104 348.0 0.1 1.0 1 0 0 1 1 1 1 Quinolinate synthetase A protein FleQ PF06490.11 AAZ34819.1 - 0.12 12.8 0.0 6 7.3 0.0 2.5 2 1 0 2 2 2 0 Flagellar regulatory protein FleQ TPM_phosphatase PF04536.14 AAZ34820.1 - 9.9e-11 41.9 0.0 8.5e-07 29.2 0.0 2.1 2 0 0 2 2 2 2 TPM domain T2SSE PF00437.20 AAZ34821.1 - 6.2e-86 287.8 3.1 8.4e-86 287.4 3.1 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.6 AAZ34821.1 - 0.0001 22.7 0.3 0.00088 19.7 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 AAZ34821.1 - 0.00043 20.6 0.0 0.0011 19.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 AAZ34821.1 - 0.0011 18.9 0.9 0.67 9.8 0.1 2.3 1 1 1 2 2 2 2 NTPase AAA_29 PF13555.6 AAZ34821.1 - 0.0033 17.1 0.1 0.007 16.1 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 AAZ34821.1 - 0.0038 17.7 0.0 0.009 16.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 AAZ34821.1 - 0.0039 17.2 0.0 0.0083 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 AAZ34821.1 - 0.0043 17.0 0.0 0.0079 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 AAZ34821.1 - 0.0056 17.2 0.0 0.012 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AAZ34821.1 - 0.009 15.8 0.3 0.031 14.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 AAZ34821.1 - 0.011 16.2 0.0 0.019 15.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 AAZ34821.1 - 0.023 14.6 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_19 PF13245.6 AAZ34821.1 - 0.04 14.3 0.3 0.13 12.5 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 AAZ34821.1 - 0.045 13.3 0.0 0.083 12.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 AAZ34821.1 - 0.045 13.6 0.0 0.066 13.1 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 AAZ34821.1 - 0.08 13.5 0.0 0.16 12.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_11 PF13086.6 AAZ34821.1 - 0.19 11.5 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain LysR_substrate PF03466.20 AAZ34822.1 - 0.0043 16.4 0.1 0.0056 16.1 0.1 1.3 1 0 0 1 1 1 1 LysR substrate binding domain ThiG PF05690.14 AAZ34823.1 - 1.8e-110 368.1 1.1 2e-110 367.9 1.1 1.0 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 AAZ34823.1 - 0.0023 17.4 0.0 0.0043 16.5 0.0 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein FMN_dh PF01070.18 AAZ34823.1 - 0.013 14.5 0.1 0.024 13.7 0.0 1.4 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Hydrolase PF00702.26 AAZ34823.1 - 0.026 14.8 0.0 0.038 14.3 0.0 1.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase IMPDH PF00478.25 AAZ34823.1 - 0.07 12.1 1.4 0.072 12.1 0.3 1.5 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Phage_AlpA PF05930.12 AAZ34824.1 - 1.1e-11 44.4 0.0 1.4e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Prophage CP4-57 regulatory protein (AlpA) HTH_17 PF12728.7 AAZ34824.1 - 1.9e-08 34.4 0.0 2.1e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain IlvN PF07991.12 AAZ34825.1 - 1e-74 249.6 2.8 1.4e-74 249.1 2.8 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 AAZ34825.1 - 2.5e-61 206.2 0.2 3.5e-61 205.7 0.2 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.19 AAZ34825.1 - 1.8e-06 27.4 0.0 3e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 AAZ34825.1 - 6.7e-06 26.4 0.2 1.7e-05 25.0 0.2 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 AAZ34825.1 - 3e-05 24.5 0.2 6.6e-05 23.4 0.2 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 AAZ34825.1 - 0.00023 21.3 0.6 0.00042 20.4 0.3 1.6 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ApbA PF02558.16 AAZ34825.1 - 0.00038 20.1 0.4 0.00091 18.9 0.4 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 AAZ34825.1 - 0.0012 19.2 0.2 0.0033 17.8 0.2 1.7 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.23 AAZ34825.1 - 0.019 15.0 0.5 1.8 8.5 0.5 2.4 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus CoA_binding PF02629.19 AAZ34825.1 - 0.042 14.5 0.3 0.12 13.1 0.3 1.8 1 0 0 1 1 1 0 CoA binding domain Xan_ur_permease PF00860.20 AAZ34826.1 - 1.9e-92 310.0 44.1 2.7e-92 309.5 44.1 1.1 1 0 0 1 1 1 1 Permease family MFS_MOT1 PF16983.5 AAZ34826.1 - 0.0016 18.9 3.0 0.0016 18.9 3.0 3.5 3 1 0 3 3 3 2 Molybdate transporter of MFS superfamily SmpA_OmlA PF04355.13 AAZ34827.1 - 1.1e-25 89.2 0.1 1.8e-25 88.5 0.1 1.3 1 0 0 1 1 1 1 SmpA / OmlA family HATPase_c PF02518.26 AAZ34828.1 - 4.2e-07 30.4 0.1 6.4e-07 29.9 0.1 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AAZ34828.1 - 0.0091 16.0 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain PhnA PF03831.14 AAZ34829.1 - 1.9e-32 110.9 8.7 2.6e-32 110.5 8.7 1.3 1 0 0 1 1 1 1 PhnA domain PhnA_Zn_Ribbon PF08274.12 AAZ34829.1 - 2.4e-16 59.4 7.3 4.2e-16 58.6 7.3 1.4 1 0 0 1 1 1 1 PhnA Zinc-Ribbon TF_Zn_Ribbon PF08271.12 AAZ34829.1 - 0.0021 17.6 0.7 0.0021 17.6 0.7 1.8 2 0 0 2 2 2 1 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.11 AAZ34829.1 - 0.0026 17.7 0.4 0.0044 16.9 0.4 1.3 1 0 0 1 1 1 1 Putative transposase DNA-binding domain zinc-ribbons_6 PF07191.12 AAZ34829.1 - 0.014 15.4 0.1 0.021 14.8 0.1 1.3 1 0 0 1 1 1 0 zinc-ribbons DUF2318 PF10080.9 AAZ34829.1 - 0.027 14.6 0.1 0.035 14.2 0.1 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2318) DNA_RNApol_7kD PF03604.13 AAZ34829.1 - 0.1 12.3 0.5 0.26 11.0 0.5 1.7 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_4 PF13717.6 AAZ34829.1 - 0.11 12.4 3.5 1.5 8.8 3.5 2.4 1 1 0 1 1 1 0 zinc-ribbon domain UPF0547 PF10571.9 AAZ34829.1 - 0.14 12.3 3.7 0.36 10.9 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-RRN7 PF11781.8 AAZ34829.1 - 0.18 11.5 2.0 0.53 10.0 2.0 1.7 1 1 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 ArsA_HSP20 PF17886.1 AAZ34829.1 - 0.19 11.3 0.6 3.9 7.1 0.1 2.8 3 1 0 3 3 3 0 HSP20-like domain found in ArsA A2L_zn_ribbon PF08792.10 AAZ34829.1 - 0.2 11.4 2.7 0.77 9.5 2.7 1.9 1 1 0 1 1 1 0 A2L zinc ribbon domain DUF4379 PF14311.6 AAZ34829.1 - 0.21 12.0 2.1 1.6 9.1 0.1 2.2 2 0 0 2 2 2 0 Probable Zinc-ribbon domain TFIIS_C PF01096.18 AAZ34829.1 - 0.22 11.4 2.7 13 5.8 0.1 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) PADR1 PF08063.12 AAZ34829.1 - 0.86 9.4 4.2 6.3 6.7 4.3 2.1 1 1 0 1 1 1 0 PADR1 (NUC008) domain Zn-ribbon_8 PF09723.10 AAZ34829.1 - 1.7 8.8 4.8 19 5.5 1.1 2.3 1 1 2 3 3 3 0 Zinc ribbon domain WavE PF07507.11 AAZ34830.1 - 2.6e-95 319.1 0.0 3e-95 318.9 0.0 1.0 1 0 0 1 1 1 1 WavE lipopolysaccharide synthesis Phage_TAC_7 PF10109.9 AAZ34831.1 - 1.1e-20 73.5 0.0 1.2e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 Phage tail assembly chaperone proteins, E, or 41 or 14 ABC_tran PF00005.27 AAZ34832.1 - 7.9e-34 117.1 0.0 1.4e-33 116.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter TOBE_2 PF08402.10 AAZ34832.1 - 7e-18 64.6 2.3 1.2e-17 63.9 0.0 2.6 4 0 0 4 4 4 1 TOBE domain SMC_N PF02463.19 AAZ34832.1 - 0.0011 18.4 0.0 0.032 13.7 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 AAZ34832.1 - 0.0058 16.2 0.4 0.055 13.0 0.0 2.4 3 0 0 3 3 3 1 AAA domain TOBE PF03459.17 AAZ34832.1 - 0.0061 16.8 0.0 0.42 10.9 0.0 3.1 2 1 0 2 2 2 1 TOBE domain DUF1513 PF07433.11 AAZ34832.1 - 0.011 14.8 0.1 0.015 14.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1513) AAA_22 PF13401.6 AAZ34832.1 - 0.029 14.6 0.5 0.065 13.5 0.5 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AAZ34832.1 - 0.091 12.5 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain PhoH PF02562.16 AAZ34832.1 - 0.1 12.0 0.2 14 5.1 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_16 PF13191.6 AAZ34832.1 - 0.12 12.7 0.0 0.32 11.4 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain FeoB_N PF02421.18 AAZ34832.1 - 0.13 11.7 0.5 0.37 10.3 0.1 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B Rad17 PF03215.15 AAZ34832.1 - 0.15 12.0 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain ArgJ PF01960.18 AAZ34833.1 - 7.9e-138 459.3 2.4 8.9e-138 459.1 2.4 1.0 1 0 0 1 1 1 1 ArgJ family Pyridoxal_deC PF00282.19 AAZ34834.1 - 2.4e-63 214.1 0.2 3.1e-63 213.8 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 AAZ34834.1 - 5.3e-07 29.2 0.1 1.6e-06 27.6 0.1 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 AAZ34834.1 - 0.0022 17.0 0.7 0.032 13.2 0.5 2.5 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 AAZ34834.1 - 0.0067 15.6 0.0 0.036 13.2 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class I and II ABC_tran PF00005.27 AAZ34835.1 - 8.1e-35 120.3 0.0 1.2e-34 119.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAZ34835.1 - 4.7e-10 39.8 0.0 0.00037 20.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAZ34835.1 - 2.2e-09 37.1 0.1 2.6e-06 27.1 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AAZ34835.1 - 7.3e-05 23.1 0.4 0.0014 19.0 0.4 2.1 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 AAZ34835.1 - 0.00062 19.4 0.0 0.46 10.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 AAZ34835.1 - 0.00067 19.7 0.2 0.23 11.4 0.1 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 AAZ34835.1 - 0.00084 19.0 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AAZ34835.1 - 0.0013 18.7 0.0 0.0029 17.5 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 AAZ34835.1 - 0.002 18.6 0.2 0.0029 18.0 0.2 1.5 1 1 0 1 1 1 1 AAA ATPase domain TniB PF05621.11 AAZ34835.1 - 0.0037 16.7 0.1 0.36 10.2 0.0 2.2 2 0 0 2 2 2 1 Bacterial TniB protein ABC_ATPase PF09818.9 AAZ34835.1 - 0.012 14.4 0.6 0.63 8.8 0.1 2.8 2 1 0 2 2 2 0 Predicted ATPase of the ABC class AAA_18 PF13238.6 AAZ34835.1 - 0.016 15.8 0.0 0.028 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AAZ34835.1 - 0.028 14.1 0.2 0.075 12.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 AAZ34835.1 - 0.033 13.7 0.0 0.053 13.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DLIC PF05783.11 AAZ34835.1 - 0.048 12.5 0.1 0.068 12.0 0.1 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA PF00004.29 AAZ34835.1 - 0.053 13.9 0.2 0.9 10.0 0.2 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 AAZ34835.1 - 0.057 13.6 0.1 0.28 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 AAZ34835.1 - 0.058 12.5 0.0 0.09 11.9 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_28 PF13521.6 AAZ34835.1 - 0.062 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AAZ34835.1 - 0.063 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 AAZ34835.1 - 0.065 12.4 0.0 0.69 9.0 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain ATP-synt_ab PF00006.25 AAZ34835.1 - 0.071 12.8 0.0 0.081 12.6 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Cytidylate_kin PF02224.18 AAZ34835.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase MMR_HSR1 PF01926.23 AAZ34835.1 - 0.13 12.3 0.0 0.31 11.1 0.0 1.7 2 0 0 2 2 1 0 50S ribosome-binding GTPase SbcCD_C PF13558.6 AAZ34835.1 - 0.14 12.4 0.2 1.7 9.0 0.2 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 AAZ34835.1 - 0.17 12.4 0.0 0.26 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 AAZ34835.1 - 0.2 11.3 0.0 0.28 10.8 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain BPD_transp_1 PF00528.22 AAZ34836.1 - 9.3e-15 54.8 14.3 9.3e-15 54.8 14.3 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component Ribosomal_S16 PF00886.19 AAZ34837.1 - 1.5e-22 79.4 0.0 2e-22 79.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 TubC_N PF18563.1 AAZ34837.1 - 0.014 15.3 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 TubC N-terminal docking domain DDDD PF10161.9 AAZ34837.1 - 0.081 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative mitochondrial precursor protein Gp138_N PF18352.1 AAZ34837.1 - 0.13 12.4 0.0 0.17 12.0 0.0 1.1 1 0 0 1 1 1 0 Phage protein Gp138 N-terminal domain Radical_SAM PF04055.21 AAZ34838.1 - 3.5e-28 99.1 0.0 5.4e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.20 AAZ34838.1 - 1.4e-27 95.5 0.0 2.9e-27 94.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 AAZ34838.1 - 3.6e-19 68.5 0.0 6.5e-19 67.7 0.0 1.5 1 0 0 1 1 1 1 TRAM domain B12-binding PF02310.19 AAZ34838.1 - 7.7e-05 22.7 0.2 0.00035 20.6 0.0 2.0 2 0 0 2 2 2 1 B12 binding domain TRAM_2 PF18693.1 AAZ34838.1 - 0.08 13.1 0.0 0.39 10.9 0.0 2.1 1 1 0 1 1 1 0 TRAM domain HATPase_c PF02518.26 AAZ34839.1 - 1.9e-20 73.4 0.0 3.4e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAZ34839.1 - 2.4e-10 40.3 0.3 5.7e-10 39.1 0.3 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 AAZ34839.1 - 1.4e-06 28.5 0.0 3e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c_2 PF13581.6 AAZ34839.1 - 0.0068 16.4 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain BRCT_3 PF18428.1 AAZ34839.1 - 0.18 11.9 0.0 0.44 10.6 0.0 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Glyco_hydro_10 PF00331.20 AAZ34840.1 - 5e-83 278.9 0.0 5.6e-83 278.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Proton_antipo_M PF00361.20 AAZ34841.1 - 2.4e-80 269.9 25.7 5.9e-80 268.6 25.7 1.7 1 0 0 1 1 1 1 Proton-conducting membrane transporter DUF3299 PF11736.8 AAZ34842.1 - 8.3e-44 148.9 0.0 1e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3299) Fe-ADH PF00465.19 AAZ34843.1 - 1.9e-125 418.5 8.0 2.1e-125 418.3 8.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 AAZ34843.1 - 9e-20 71.4 3.6 1.4e-10 41.3 0.0 2.1 1 1 1 2 2 2 2 Iron-containing alcohol dehydrogenase Lamprin PF06403.11 AAZ34843.1 - 0.027 14.4 0.7 0.069 13.1 0.7 1.7 1 0 0 1 1 1 0 Lamprin Glucosamine_iso PF01182.20 AAZ34844.1 - 3.8e-56 190.5 0.0 4.3e-56 190.3 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase baeRF_family10 PF18854.1 AAZ34844.1 - 0.11 12.8 0.2 0.61 10.3 0.1 2.1 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 10 Bac_luciferase PF00296.20 AAZ34845.1 - 1.6e-63 215.1 0.0 2.1e-63 214.7 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase MFS_1 PF07690.16 AAZ34847.1 - 1.5e-38 132.6 89.3 2.1e-36 125.6 50.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AAZ34847.1 - 1.5e-09 37.3 16.8 1.5e-09 37.3 16.8 3.0 1 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 AAZ34847.1 - 1.3e-06 28.0 48.0 1.5e-06 27.8 48.0 1.0 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB ABC_tran PF00005.27 AAZ34848.1 - 1e-25 90.9 0.0 1.3e-25 90.5 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAZ34848.1 - 4e-05 23.6 0.2 0.01 15.7 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAZ34848.1 - 6e-05 22.6 0.0 0.31 10.5 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AAZ34848.1 - 0.00083 19.8 0.0 0.0012 19.2 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AAZ34848.1 - 0.0098 15.6 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AAZ34848.1 - 0.015 15.8 0.0 0.022 15.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.8 AAZ34848.1 - 0.022 12.3 0.0 0.029 11.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) T2SSE PF00437.20 AAZ34848.1 - 0.056 12.5 0.0 0.078 12.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.19 AAZ34848.1 - 0.088 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 AAZ34848.1 - 0.2 12.1 0.0 0.44 11.0 0.0 1.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 AAZ34848.1 - 0.24 10.7 0.0 0.36 10.1 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_15 PF13175.6 AAZ34848.1 - 0.32 10.7 0.0 0.52 10.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Cupin_2 PF07883.11 AAZ34849.1 - 1.1e-12 47.4 0.1 1.6e-12 46.9 0.1 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 AAZ34849.1 - 0.00078 19.4 0.2 0.0015 18.4 0.0 1.5 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_3 PF05899.12 AAZ34849.1 - 0.0071 16.0 0.0 0.015 15.0 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_1 PF00190.22 AAZ34849.1 - 0.023 14.3 0.1 0.045 13.3 0.1 1.4 2 0 0 2 2 2 0 Cupin Clenterotox PF03505.14 AAZ34849.1 - 0.085 12.4 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Clostridium enterotoxin TetR_C_7 PF14246.6 AAZ34850.1 - 2.7e-22 79.0 2.9 4.7e-22 78.3 0.6 2.1 2 0 0 2 2 2 1 AefR-like transcriptional repressor, C-terminal domain TetR_N PF00440.23 AAZ34850.1 - 7.6e-17 60.8 0.1 2e-16 59.5 0.1 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_Tnp_1_2 PF13022.6 AAZ34850.1 - 6.1e-05 23.2 0.1 0.00017 21.7 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix of insertion element transposase KfrA_N PF11740.8 AAZ34850.1 - 0.0028 18.3 0.1 0.04 14.6 0.0 2.1 2 0 0 2 2 2 1 Plasmid replication region DNA-binding N-term HTH_22 PF13309.6 AAZ34850.1 - 0.019 15.0 0.1 0.066 13.3 0.0 1.9 2 0 0 2 2 2 0 HTH domain Coprogen_oxidas PF01218.18 AAZ34851.1 - 4.6e-131 435.9 0.0 5.3e-131 435.7 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Acetyltransf_1 PF00583.25 AAZ34853.1 - 7.1e-07 29.5 0.0 1.9e-06 28.1 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAZ34853.1 - 0.03 14.7 0.0 0.045 14.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RibD_C PF01872.17 AAZ34854.1 - 8.8e-48 162.8 0.0 1.6e-47 161.9 0.0 1.4 2 0 0 2 2 2 1 RibD C-terminal domain dCMP_cyt_deam_1 PF00383.23 AAZ34854.1 - 3.4e-20 71.8 0.0 7.1e-20 70.8 0.0 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 AAZ34854.1 - 2.9e-13 49.7 0.0 4.5e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase STAS PF01740.21 AAZ34854.1 - 0.099 12.3 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 STAS domain APOBEC_N PF08210.11 AAZ34854.1 - 0.16 11.8 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 APOBEC-like N-terminal domain Esterase PF00756.20 AAZ34855.1 - 1.9e-64 217.7 0.0 2.2e-64 217.5 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Esterase_phd PF10503.9 AAZ34855.1 - 1.2e-06 28.2 0.0 5.7e-06 26.0 0.0 2.0 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 AAZ34855.1 - 0.00018 21.0 0.0 0.00031 20.3 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 AAZ34855.1 - 0.00041 19.7 0.0 0.00099 18.4 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 AAZ34855.1 - 0.0054 15.7 0.0 0.0082 15.1 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_1 PF00561.20 AAZ34855.1 - 0.014 15.1 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Acetyltransf_3 PF13302.7 AAZ34856.1 - 8.6e-17 62.1 0.0 1.1e-16 61.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AAZ34856.1 - 8.1e-09 35.8 0.0 8.1e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAZ34856.1 - 1.3e-07 31.9 0.0 1.7e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 AAZ34856.1 - 0.00044 19.9 0.0 0.0008 19.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAZ34856.1 - 0.13 12.2 0.0 0.28 11.2 0.0 1.5 1 1 0 1 1 1 0 FR47-like protein PCMT PF01135.19 AAZ34857.1 - 1.1e-64 218.0 0.0 1.3e-64 217.8 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 AAZ34857.1 - 0.00021 21.1 0.0 0.00039 20.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 AAZ34857.1 - 0.0023 17.1 0.0 0.0032 16.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 AAZ34857.1 - 0.0067 17.1 0.0 0.011 16.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAZ34857.1 - 0.0076 16.9 0.0 0.018 15.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 AAZ34857.1 - 0.012 15.3 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_23 PF13489.6 AAZ34857.1 - 0.05 13.4 0.0 0.19 11.5 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_24 PF13578.6 AAZ34857.1 - 0.11 13.6 0.2 1.5 9.9 0.1 2.4 2 1 1 3 3 3 0 Methyltransferase domain Abhydrolase_1 PF00561.20 AAZ34858.1 - 8.9e-28 97.6 0.1 1.2e-27 97.2 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 AAZ34858.1 - 0.0044 16.7 0.0 0.0067 16.1 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 AAZ34858.1 - 0.009 15.3 0.0 0.046 13.0 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AAZ34859.1 - 6e-31 108.0 0.0 1.3e-29 103.7 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AAZ34859.1 - 8e-22 77.7 0.0 2.4e-21 76.1 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AAZ34859.1 - 5e-21 76.3 0.1 6.5e-21 75.9 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 AAZ34859.1 - 3.3e-07 30.0 0.1 3.8e-05 23.3 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 AAZ34859.1 - 6.8e-07 29.1 0.0 2.1e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family DUF915 PF06028.11 AAZ34859.1 - 0.00011 21.6 0.0 0.00035 20.0 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) DUF1100 PF06500.11 AAZ34859.1 - 0.0009 18.1 0.0 0.0013 17.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_2 PF02230.16 AAZ34859.1 - 0.0022 17.8 0.0 0.14 11.9 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.10 AAZ34859.1 - 0.0035 17.4 0.0 0.006 16.7 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Esterase_phd PF10503.9 AAZ34859.1 - 0.026 14.0 0.1 0.044 13.3 0.1 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase FSH1 PF03959.13 AAZ34859.1 - 0.056 13.1 0.0 0.19 11.3 0.0 1.9 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.7 AAZ34859.1 - 0.075 12.8 0.0 7.4 6.3 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 AAZ34859.1 - 0.13 11.8 0.0 5.3 6.6 0.0 2.2 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) HI0933_like PF03486.14 AAZ34860.1 - 5.9e-111 371.1 0.0 6.7e-111 370.9 0.0 1.0 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 AAZ34860.1 - 2.8e-06 27.5 0.1 8.3e-06 26.0 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AAZ34860.1 - 7.1e-06 25.5 0.0 8e-05 22.0 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AAZ34860.1 - 2.1e-05 23.8 0.1 0.0012 18.0 0.1 2.7 3 0 0 3 3 3 1 FAD binding domain FAD_binding_3 PF01494.19 AAZ34860.1 - 2.4e-05 23.8 0.2 3.7e-05 23.1 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 AAZ34860.1 - 0.00024 21.6 0.0 0.06 13.9 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 AAZ34860.1 - 0.0026 17.1 0.0 0.0042 16.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 AAZ34860.1 - 0.0035 16.5 1.3 0.012 14.7 0.6 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 AAZ34860.1 - 0.0052 16.1 0.0 0.0086 15.4 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 AAZ34860.1 - 0.0056 16.3 2.0 0.5 9.9 0.6 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 AAZ34860.1 - 0.021 13.9 0.2 0.034 13.2 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 AAZ34860.1 - 0.042 13.1 0.4 0.067 12.4 0.4 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 AAZ34860.1 - 0.051 13.5 0.1 0.079 12.8 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 AAZ34860.1 - 0.054 12.8 0.0 0.066 12.5 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 AAZ34860.1 - 0.084 11.7 0.1 0.12 11.2 0.1 1.1 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.6 AAZ34860.1 - 0.11 12.5 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding HPPK PF01288.20 AAZ34861.1 - 2.1e-19 70.1 0.0 2.9e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) CcmE PF03100.15 AAZ34862.1 - 2.7e-45 153.5 0.0 3.1e-45 153.3 0.0 1.0 1 0 0 1 1 1 1 CcmE Fer4_21 PF14697.6 AAZ34864.1 - 7.3e-17 61.2 16.7 7.3e-17 61.2 16.7 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain FeS PF04060.13 AAZ34864.1 - 9.3e-13 47.6 6.2 3.8e-12 45.6 6.2 2.2 1 0 0 1 1 1 1 Putative Fe-S cluster Fer4 PF00037.27 AAZ34864.1 - 3.8e-08 32.8 30.5 6.7e-06 25.7 5.2 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_7 PF12838.7 AAZ34864.1 - 4.8e-07 30.3 43.2 7.4e-05 23.3 17.4 2.9 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAZ34864.1 - 3e-06 27.3 13.0 3e-06 27.3 13.0 2.7 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAZ34864.1 - 3.3e-06 27.2 33.6 1.7e-05 24.8 15.3 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAZ34864.1 - 0.00086 20.2 3.2 0.00086 20.2 3.2 3.5 2 1 0 3 3 2 2 4Fe-4S double cluster binding domain Fer4_6 PF12837.7 AAZ34864.1 - 0.0049 16.9 4.6 0.0049 16.9 4.6 3.3 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_2 PF12797.7 AAZ34864.1 - 0.0071 16.4 2.3 0.0071 16.4 2.3 3.3 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_3 PF12798.7 AAZ34864.1 - 0.011 16.6 4.7 0.011 16.6 4.7 3.6 4 0 0 4 4 4 0 4Fe-4S binding domain Fer4_22 PF17179.4 AAZ34864.1 - 0.12 13.2 0.9 0.12 13.2 0.9 3.1 4 0 0 4 4 3 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 AAZ34864.1 - 0.39 11.3 24.7 0.38 11.4 3.9 3.4 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_18 PF13746.6 AAZ34864.1 - 0.72 10.1 16.4 1 9.6 3.6 2.7 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 AAZ34864.1 - 6.7 7.2 25.5 1.2 9.6 4.2 3.4 1 1 3 4 4 4 0 4Fe-4S dicluster domain Sel1 PF08238.12 AAZ34866.1 - 0.00026 21.6 1.4 0.00026 21.6 1.4 3.2 2 1 0 2 2 2 1 Sel1 repeat SBP_bac_3 PF00497.20 AAZ34867.1 - 1.9e-48 164.8 1.2 3e-48 164.2 0.9 1.4 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1 PF09084.11 AAZ34867.1 - 0.00012 22.1 0.4 0.00021 21.3 0.4 1.4 1 1 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.7 AAZ34867.1 - 0.0002 21.0 0.1 0.00036 20.2 0.1 1.4 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein TDH PF03347.13 AAZ34867.1 - 0.025 14.1 0.1 0.059 12.9 0.1 1.6 2 0 0 2 2 2 0 Vibrio thermostable direct hemolysin Pirin PF02678.16 AAZ34868.1 - 2.7e-34 117.4 0.4 3.9e-34 116.9 0.4 1.2 1 0 0 1 1 1 1 Pirin Pirin_C_2 PF17954.1 AAZ34868.1 - 1.7e-26 92.2 0.1 5.4e-26 90.6 0.0 1.8 2 0 0 2 2 2 1 Quercetinase C-terminal cupin domain Cupin_2 PF07883.11 AAZ34868.1 - 7.6e-05 22.3 1.0 0.00018 21.1 1.0 1.7 1 0 0 1 1 1 1 Cupin domain LysR_substrate PF03466.20 AAZ34869.1 - 1.2e-46 158.8 1.5 1.6e-46 158.3 1.5 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ34869.1 - 6e-27 93.4 0.5 1.5e-26 92.1 0.5 1.8 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AAZ34869.1 - 3.2e-05 23.6 0.1 9.5e-05 22.1 0.1 1.8 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain MarR_2 PF12802.7 AAZ34869.1 - 0.016 15.1 0.3 0.016 15.1 0.3 2.9 4 0 0 4 4 4 0 MarR family HTH_5 PF01022.20 AAZ34869.1 - 0.037 13.9 0.1 0.083 12.8 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family SBP_bac_11 PF13531.6 AAZ34869.1 - 0.043 13.5 0.3 0.33 10.7 0.2 2.4 1 1 1 2 2 2 0 Bacterial extracellular solute-binding protein HTH_28 PF13518.6 AAZ34869.1 - 0.15 12.2 0.1 0.37 11.0 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain PIG-L PF02585.17 AAZ34870.1 - 8.3e-15 55.6 0.0 1.3e-14 54.9 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase BCD PF15461.6 AAZ34870.1 - 0.005 16.4 0.2 0.0078 15.7 0.2 1.2 1 0 0 1 1 1 1 Beta-carotene 15,15'-dioxygenase ABC_tran PF00005.27 AAZ34871.1 - 1.4e-35 122.8 0.0 2.3e-35 122.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter NIL PF09383.10 AAZ34871.1 - 5.9e-16 58.1 0.1 1.4e-15 56.9 0.1 1.7 1 0 0 1 1 1 1 NIL domain AAA_21 PF13304.6 AAZ34871.1 - 4.1e-08 33.4 0.6 0.0047 16.8 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAZ34871.1 - 5e-06 26.1 0.3 0.0012 18.3 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AAZ34871.1 - 0.0011 19.2 0.1 0.0073 16.6 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAZ34871.1 - 0.0027 18.1 1.8 0.0095 16.3 0.8 2.4 2 1 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 AAZ34871.1 - 0.0081 16.1 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 AAZ34871.1 - 0.012 15.4 0.0 0.028 14.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.6 AAZ34871.1 - 0.013 15.7 0.5 0.34 11.2 0.1 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 AAZ34871.1 - 0.016 15.3 0.0 0.039 14.1 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase TniB PF05621.11 AAZ34871.1 - 0.024 14.0 0.1 2.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_30 PF13604.6 AAZ34871.1 - 0.077 12.7 0.0 0.87 9.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 AAZ34871.1 - 0.089 13.3 0.1 0.18 12.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 AAZ34871.1 - 0.42 9.4 1.4 22 3.7 0.1 2.8 2 1 0 2 2 2 0 Predicted ATPase of the ABC class 2-Hacid_dh_C PF02826.19 AAZ34872.1 - 2.9e-60 202.7 0.0 5.5e-60 201.8 0.0 1.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 AAZ34872.1 - 4.8e-27 94.2 0.0 5.6e-27 94.0 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 AAZ34872.1 - 9e-05 22.7 0.0 0.00017 21.8 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 AAZ34872.1 - 0.00033 21.2 0.0 0.0013 19.3 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 AAZ34872.1 - 0.013 15.1 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 AAZ34872.1 - 0.016 14.5 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HhH-GPD PF00730.25 AAZ34873.1 - 8.2e-22 77.7 0.0 1.3e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 AAZ34873.1 - 7.9e-09 34.9 0.0 1.9e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 AAZ34873.1 - 0.0023 18.2 4.8 0.0039 17.5 4.8 1.4 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III HHH_5 PF14520.6 AAZ34873.1 - 0.01 16.4 0.1 0.51 11.0 0.0 2.0 1 1 2 3 3 3 0 Helix-hairpin-helix domain DUF4817 PF16087.5 AAZ34873.1 - 0.016 15.0 0.0 0.68 9.8 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain (DUF4817) HHH_8 PF14716.6 AAZ34873.1 - 0.094 13.1 0.0 0.66 10.4 0.0 2.3 1 1 1 2 2 2 0 Helix-hairpin-helix domain Ferrochelatase PF00762.19 AAZ34874.1 - 2.3e-97 325.9 0.0 2.8e-97 325.6 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.17 AAZ34874.1 - 7.3e-07 29.5 0.0 0.0054 17.0 0.0 2.5 2 1 0 2 2 2 2 CbiX CbiK PF06180.11 AAZ34874.1 - 0.0023 17.3 0.0 0.004 16.5 0.0 1.3 1 0 0 1 1 1 1 Cobalt chelatase (CbiK) Gcw_chp PF09694.10 AAZ34875.1 - 2.1e-10 41.0 3.3 9.8e-10 38.8 3.3 1.9 1 1 0 1 1 1 1 Bacterial protein of unknown function (Gcw_chp) LptD PF04453.14 AAZ34876.1 - 5.7e-128 427.4 24.0 9.8e-128 426.7 24.0 1.4 1 0 0 1 1 1 1 LPS transport system D OstA PF03968.14 AAZ34876.1 - 4.7e-13 49.3 0.6 1.1e-12 48.1 0.6 1.6 1 0 0 1 1 1 1 OstA-like protein OstA_2 PF13100.6 AAZ34876.1 - 0.031 13.9 0.1 0.077 12.6 0.1 1.6 1 0 0 1 1 1 0 OstA-like protein LptC PF06835.13 AAZ34876.1 - 0.12 12.0 0.2 0.41 10.2 0.2 2.0 1 1 0 1 1 1 0 Lipopolysaccharide-assembly, LptC-related PASTA PF03793.19 AAZ34876.1 - 0.22 11.4 0.7 0.56 10.1 0.7 1.7 1 0 0 1 1 1 0 PASTA domain Caskin1-CID PF16600.5 AAZ34876.1 - 0.55 10.8 2.6 1.7 9.3 2.6 1.8 1 0 0 1 1 1 0 Caskin1 CASK-interaction domain Big_9 PF17963.1 AAZ34876.1 - 7.1 7.4 9.1 28 5.6 0.2 4.1 4 1 1 5 5 5 0 Bacterial Ig domain DUF2070 PF09843.9 AAZ34877.1 - 0.021 13.1 1.9 0.027 12.8 1.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Ribosomal_L12 PF00542.19 AAZ34878.1 - 0.0016 18.8 0.3 0.0028 18.0 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L7/L12 C-terminal domain DNA_gyraseB PF00204.25 AAZ34879.1 - 7.3e-57 191.6 0.2 1.3e-56 190.8 0.2 1.4 1 0 0 1 1 1 1 DNA gyrase B GyrB_insert PF18053.1 AAZ34879.1 - 1.2e-52 178.1 0.0 2e-52 177.5 0.0 1.4 1 0 0 1 1 1 1 DNA gyrase B subunit insert domain DNA_gyraseB_C PF00986.21 AAZ34879.1 - 2.6e-30 104.4 0.1 6e-30 103.2 0.1 1.7 1 0 0 1 1 1 1 DNA gyrase B subunit, carboxyl terminus HATPase_c PF02518.26 AAZ34879.1 - 3.7e-22 79.0 0.3 1.3e-21 77.2 0.2 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 AAZ34879.1 - 1.6e-17 63.6 0.0 5.6e-17 61.9 0.0 2.0 2 0 0 2 2 2 1 Toprim domain HATPase_c_3 PF13589.6 AAZ34879.1 - 9.8e-05 22.2 0.0 0.00024 20.9 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ketoacyl-synt PF00109.26 AAZ34880.1 - 2.2e-45 155.2 0.9 3.5e-45 154.6 0.9 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 AAZ34880.1 - 3.5e-31 107.7 0.8 2.8e-30 104.7 0.4 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 AAZ34880.1 - 0.00075 18.9 5.7 0.006 16.0 1.0 2.8 2 1 1 3 3 3 2 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 AAZ34880.1 - 0.0098 16.3 0.0 0.02 15.3 0.0 1.5 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension 2-Hacid_dh_C PF02826.19 AAZ34881.1 - 9.2e-51 171.7 0.0 1.7e-50 170.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 AAZ34881.1 - 1.6e-38 131.4 0.0 2.1e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 AAZ34881.1 - 5.6e-05 23.4 0.3 0.00015 22.0 0.2 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.25 AAZ34881.1 - 7.5e-05 22.4 0.0 0.00019 21.1 0.0 1.6 1 0 0 1 1 1 1 ACT domain IlvN PF07991.12 AAZ34881.1 - 0.0014 18.2 0.1 0.005 16.4 0.0 2.0 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 AAZ34881.1 - 0.0025 17.1 0.1 0.054 12.8 0.1 2.4 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ACT_4 PF13291.6 AAZ34881.1 - 0.031 14.9 0.1 0.069 13.7 0.1 1.5 1 0 0 1 1 1 0 ACT domain Csm4_C PF17953.1 AAZ34881.1 - 0.037 13.9 0.0 11 5.9 0.0 2.4 2 0 0 2 2 2 0 CRISPR Csm4 C-terminal domain AdoHcyase_NAD PF00670.21 AAZ34881.1 - 0.051 13.7 0.0 0.098 12.7 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain PilM_2 PF11104.8 AAZ34881.1 - 0.083 11.9 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; KfrA_N PF11740.8 AAZ34883.1 - 2.2e-18 67.0 11.0 2.2e-18 67.0 11.0 5.4 1 1 1 2 2 1 1 Plasmid replication region DNA-binding N-term TPR_MLP1_2 PF07926.12 AAZ34883.1 - 0.00033 20.7 62.2 0.012 15.7 28.0 3.0 1 1 2 3 3 3 2 TPR/MLP1/MLP2-like protein Tropomyosin_1 PF12718.7 AAZ34883.1 - 0.006 16.7 10.0 0.006 16.7 10.0 3.8 1 1 2 3 3 3 2 Tropomyosin like Phage_GP20 PF06810.11 AAZ34883.1 - 0.024 14.4 32.1 0.059 13.2 6.4 3.9 1 1 2 3 3 3 0 Phage minor structural protein GP20 DUF3584 PF12128.8 AAZ34883.1 - 0.031 11.8 51.9 0.04 11.5 51.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4686 PF15742.5 AAZ34883.1 - 0.12 11.5 62.7 0.016 14.4 49.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4686) Uso1_p115_C PF04871.13 AAZ34883.1 - 0.38 11.1 51.1 0.031 14.6 13.6 3.4 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Fez1 PF06818.15 AAZ34883.1 - 0.67 10.4 50.2 2.6 8.5 29.9 2.9 1 1 1 2 2 2 0 Fez1 Fib_alpha PF08702.10 AAZ34883.1 - 1.9 8.7 34.3 3.5 7.8 4.9 3.3 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family YtxH PF12732.7 AAZ34883.1 - 2.1 8.9 6.0 0.71 10.4 0.2 2.8 3 0 0 3 3 3 0 YtxH-like protein ATG16 PF08614.11 AAZ34883.1 - 5.3 7.2 64.7 0.34 11.1 42.1 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) FlaC_arch PF05377.11 AAZ34883.1 - 7 7.1 19.3 11 6.4 0.9 5.0 4 1 2 6 6 6 0 Flagella accessory protein C (FlaC) Spc7 PF08317.11 AAZ34883.1 - 8 5.2 53.2 2.4 6.9 30.9 2.7 1 1 1 2 2 2 0 Spc7 kinetochore protein Sec8_exocyst PF04048.14 AAZ34883.1 - 9.5 6.1 29.6 3 7.7 5.9 4.1 1 1 3 4 4 4 0 Sec8 exocyst complex component specific domain GTP_EFTU PF00009.27 AAZ34884.1 - 5.4e-36 124.0 1.0 2.6e-34 118.5 1.0 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 AAZ34884.1 - 4.1e-34 116.9 0.1 9.2e-34 115.7 0.1 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 IF2_N PF04760.15 AAZ34884.1 - 3.2e-23 81.3 2.6 3.2e-15 55.7 0.2 2.6 2 0 0 2 2 2 2 Translation initiation factor IF-2, N-terminal region IF2_assoc PF08364.11 AAZ34884.1 - 7.1e-10 39.0 8.3 7.1e-10 39.0 8.3 2.4 2 0 0 2 2 2 1 Bacterial translation initiation factor IF-2 associated region MMR_HSR1 PF01926.23 AAZ34884.1 - 6.6e-09 35.9 0.1 1.7e-08 34.5 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 AAZ34884.1 - 4.1e-08 33.5 2.5 0.0012 19.2 0.2 3.5 2 1 0 2 2 2 2 Elongation factor Tu domain 2 FeoB_N PF02421.18 AAZ34884.1 - 5.6e-05 22.7 0.0 0.00014 21.5 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B Ras PF00071.22 AAZ34884.1 - 6e-05 22.7 0.0 0.00013 21.6 0.0 1.6 1 0 0 1 1 1 1 Ras family Arf PF00025.21 AAZ34884.1 - 0.0018 17.8 0.0 0.0035 16.8 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family MeaB PF03308.16 AAZ34884.1 - 0.0039 16.2 0.1 0.0039 16.2 0.1 2.6 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRPRB PF09439.10 AAZ34884.1 - 0.0086 15.5 1.7 0.033 13.6 0.0 2.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_26 PF13500.6 AAZ34884.1 - 0.029 14.2 0.0 10 5.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 AAZ34884.1 - 0.06 13.6 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 AAZ34884.1 - 0.18 11.8 1.2 5.5 7.0 0.0 2.9 2 1 1 3 3 3 0 Dynamin family DUF3828 PF12883.7 AAZ34885.1 - 6.9e-06 26.4 0.1 1e-05 25.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3828) Glyoxalase PF00903.25 AAZ34887.1 - 6.2e-09 36.1 0.0 2.1e-08 34.4 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 AAZ34887.1 - 6.7e-08 32.5 0.0 2.9e-07 30.4 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase-like domain Secretin PF00263.21 AAZ34888.1 - 8.1e-44 149.3 0.0 1.2e-43 148.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial type II and III secretion system protein T2SS-T3SS_pil_N PF13629.6 AAZ34888.1 - 3.8e-18 65.0 0.3 8.4e-18 63.9 0.3 1.6 1 0 0 1 1 1 1 Pilus formation protein N terminal region APS_kinase PF01583.20 AAZ34889.1 - 8e-67 224.0 0.0 9.8e-67 223.8 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_18 PF13238.6 AAZ34889.1 - 4.1e-07 30.6 0.0 6.1e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AAZ34889.1 - 2e-06 28.0 0.0 3e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 AAZ34889.1 - 0.00039 19.8 0.0 0.00054 19.3 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.6 AAZ34889.1 - 0.00094 18.9 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AAZ34889.1 - 0.0018 18.7 0.1 0.0026 18.2 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 AAZ34889.1 - 0.022 14.3 1.2 4.1 6.9 0.0 2.1 1 1 1 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 AAZ34889.1 - 0.029 14.1 0.0 5.5 6.7 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase KTI12 PF08433.10 AAZ34889.1 - 0.05 13.0 0.0 0.075 12.5 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_22 PF13401.6 AAZ34889.1 - 0.059 13.7 0.0 0.12 12.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AAZ34889.1 - 0.062 13.8 0.0 0.083 13.4 0.0 1.3 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 AAZ34889.1 - 0.066 13.6 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 AAZ34889.1 - 0.12 12.1 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AAZ34889.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 AAZ34889.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase Parvo_NS1 PF01057.17 AAZ34889.1 - 0.14 11.3 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 N_methyl PF07963.12 AAZ34890.1 - 2.3e-08 33.2 1.4 3.8e-08 32.5 1.4 1.4 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif CbiA PF01656.23 AAZ34891.1 - 8.9e-20 71.0 0.2 1.2e-19 70.7 0.2 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 AAZ34891.1 - 6.9e-19 68.4 0.1 1.3e-18 67.5 0.1 1.4 1 1 0 1 1 1 1 AAA domain ParA PF10609.9 AAZ34891.1 - 3.1e-15 56.3 1.2 4.4e-14 52.5 1.2 2.4 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase MipZ PF09140.11 AAZ34891.1 - 2.8e-08 33.4 0.4 5.3e-08 32.5 0.4 1.5 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 AAZ34891.1 - 5.6e-08 32.3 4.2 1.6e-07 30.8 3.2 2.1 1 1 0 2 2 2 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 AAZ34891.1 - 8.5e-08 32.0 0.1 2.1e-07 30.7 0.1 1.4 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 AAZ34891.1 - 0.00043 19.8 1.1 0.01 15.3 0.6 2.3 1 1 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_24 PF13479.6 AAZ34891.1 - 0.0013 18.5 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain CLP1_P PF16575.5 AAZ34891.1 - 0.024 14.4 0.2 0.053 13.3 0.1 1.6 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop CobA_CobO_BtuR PF02572.15 AAZ34891.1 - 0.11 12.8 0.1 0.18 12.0 0.1 1.5 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP SRP54 PF00448.22 AAZ34891.1 - 0.23 11.1 2.7 0.35 10.5 1.1 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MCPsignal PF00015.21 AAZ34892.1 - 8.2e-38 129.9 20.8 1e-37 129.6 19.1 1.9 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain PAS_3 PF08447.12 AAZ34892.1 - 6.3e-36 122.6 0.0 1.2e-17 63.9 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 AAZ34892.1 - 1.4e-25 89.6 0.0 3.6e-11 43.3 0.0 2.9 3 1 1 4 4 4 2 PAS fold PAS_9 PF13426.7 AAZ34892.1 - 1.9e-23 82.7 0.0 3.2e-10 40.2 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 AAZ34892.1 - 2.2e-11 43.7 0.0 0.00023 21.1 0.0 2.9 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 AAZ34892.1 - 0.00053 19.9 0.0 1.1 9.4 0.0 2.7 2 0 0 2 2 2 2 PAS domain DUF3562 PF12085.8 AAZ34892.1 - 0.024 14.2 0.2 4.5 7.0 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3562) DUF2733 PF10813.8 AAZ34892.1 - 0.21 11.4 0.0 20 5.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2733) T7SS_ESX_EspC PF10824.8 AAZ34892.1 - 2.3 8.8 10.2 1.6 9.2 0.9 3.1 1 1 2 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm GGDEF PF00990.21 AAZ34893.1 - 1.7e-45 154.7 0.0 6.2e-45 152.8 0.0 2.0 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain GGDEF_2 PF17853.1 AAZ34893.1 - 0.0006 20.0 2.7 0.0021 18.3 0.0 3.1 3 1 0 3 3 3 1 GGDEF-like domain T3SS_needle_reg PF09025.10 AAZ34893.1 - 0.026 14.5 0.1 0.1 12.6 0.1 2.0 1 0 0 1 1 1 0 YopR, type III needle-polymerisation regulator Baculo_PEP_C PF04513.12 AAZ34893.1 - 0.065 13.3 2.0 0.95 9.5 0.8 2.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Golgin_A5 PF09787.9 AAZ34893.1 - 0.17 11.3 6.7 0.4 10.1 6.7 1.6 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF2850 PF11012.8 AAZ34893.1 - 0.21 11.9 0.0 0.48 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2850) CCDC144C PF14915.6 AAZ34893.1 - 0.37 9.9 7.7 0.31 10.1 2.8 2.4 1 1 0 2 2 2 0 CCDC144C protein coiled-coil region Gp58 PF07902.11 AAZ34893.1 - 1.8 6.8 4.5 2.8 6.1 4.5 1.2 1 0 0 1 1 1 0 gp58-like protein Sigma54_activat PF00158.26 AAZ34894.1 - 1.2e-57 194.2 0.0 2.4e-57 193.3 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AAZ34894.1 - 1e-17 64.5 0.0 3.2e-17 62.9 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 AAZ34894.1 - 6.7e-10 38.6 0.7 6.7e-10 38.6 0.7 2.3 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 AAZ34894.1 - 3e-09 37.0 0.0 5.1e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 AAZ34894.1 - 8.9e-05 22.9 0.0 0.00016 22.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 AAZ34894.1 - 0.00023 20.6 0.1 0.16 11.3 0.0 2.2 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI MCM PF00493.23 AAZ34894.1 - 0.0013 17.9 0.1 0.0032 16.6 0.1 1.6 1 1 0 1 1 1 1 MCM P-loop domain AAA_2 PF07724.14 AAZ34894.1 - 0.0017 18.5 0.0 0.0036 17.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 AAZ34894.1 - 0.051 14.0 1.3 0.091 13.1 0.3 2.0 2 1 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 AAZ34894.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region LcrG PF07216.12 AAZ34895.1 - 0.014 15.3 0.2 0.017 15.0 0.2 1.1 1 0 0 1 1 1 0 LcrG protein ATP-synt_DE PF00401.20 AAZ34895.1 - 0.74 10.1 5.1 4.4 7.7 0.2 2.1 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain CBS PF00571.28 AAZ34896.1 - 9.2e-27 93.3 1.9 5.3e-13 49.2 0.3 2.2 2 0 0 2 2 2 2 CBS domain DeoRC PF00455.22 AAZ34897.1 - 5.6e-39 133.6 0.0 7.2e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 DeoR C terminal sensor domain HTH_DeoR PF08220.12 AAZ34897.1 - 2e-17 62.7 0.7 4.7e-17 61.5 0.2 1.9 2 0 0 2 2 2 1 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 AAZ34897.1 - 5.7e-07 29.4 0.1 1.2e-06 28.4 0.1 1.5 1 0 0 1 1 1 1 HTH domain HTH_5 PF01022.20 AAZ34897.1 - 4e-06 26.6 0.1 8.2e-06 25.6 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family GntR PF00392.21 AAZ34897.1 - 4.5e-06 26.2 0.2 2.5e-05 23.8 0.1 2.2 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_29 PF13551.6 AAZ34897.1 - 1.3e-05 25.1 0.1 3.3e-05 23.8 0.1 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 AAZ34897.1 - 0.00023 21.2 0.0 0.00087 19.4 0.0 2.0 2 0 0 2 2 1 1 Helix-turn-helix domain MarR_2 PF12802.7 AAZ34897.1 - 0.00083 19.2 0.3 0.003 17.4 0.3 1.9 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 AAZ34897.1 - 0.0012 18.9 0.4 0.0071 16.4 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 AAZ34897.1 - 0.0013 18.4 0.0 0.003 17.3 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain TrmB PF01978.19 AAZ34897.1 - 0.0019 18.0 0.0 0.0039 17.0 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_Mga PF08280.11 AAZ34897.1 - 0.0021 18.1 0.0 0.004 17.1 0.0 1.5 1 0 0 1 1 1 1 M protein trans-acting positive regulator (MGA) HTH domain HTH_Tnp_ISL3 PF13542.6 AAZ34897.1 - 0.0021 17.4 0.0 0.0057 16.0 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_IclR PF09339.10 AAZ34897.1 - 0.0031 17.3 0.2 0.01 15.7 0.2 1.9 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_24 PF13412.6 AAZ34897.1 - 0.0046 16.5 0.3 0.018 14.6 0.1 2.0 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding RP-C PF03428.13 AAZ34897.1 - 0.0084 15.8 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 Replication protein C N-terminal domain GerE PF00196.19 AAZ34897.1 - 0.0093 15.5 0.1 0.038 13.5 0.0 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family PaaX PF07848.12 AAZ34897.1 - 0.011 16.0 0.0 0.023 14.9 0.0 1.5 1 0 0 1 1 1 0 PaaX-like protein DprA_WH PF17782.1 AAZ34897.1 - 0.012 15.8 0.4 0.012 15.8 0.4 2.3 3 0 0 3 3 2 0 DprA winged helix domain HTH_36 PF13730.6 AAZ34897.1 - 0.021 14.8 0.0 0.042 13.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 AAZ34897.1 - 0.028 14.4 0.1 0.099 12.6 0.1 1.9 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Sigma70_r4_2 PF08281.12 AAZ34897.1 - 0.033 13.9 0.6 0.13 12.0 0.0 2.3 3 0 0 3 3 3 0 Sigma-70, region 4 HTH_Tnp_1 PF01527.20 AAZ34897.1 - 0.082 13.2 0.0 0.26 11.6 0.0 1.8 1 0 0 1 1 1 0 Transposase MarR PF01047.22 AAZ34897.1 - 0.088 12.7 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 MarR family NAD_binding_3 PF03447.16 AAZ34897.1 - 0.089 13.5 0.2 0.57 10.8 0.0 2.2 2 1 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain Mga PF05043.13 AAZ34897.1 - 0.091 13.3 0.0 0.24 12.0 0.0 1.6 1 0 0 1 1 1 0 Mga helix-turn-helix domain SpoIIID PF12116.8 AAZ34897.1 - 0.12 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Stage III sporulation protein D Fe_dep_repress PF01325.19 AAZ34897.1 - 0.16 12.2 0.1 0.82 9.9 0.0 2.2 3 0 0 3 3 3 0 Iron dependent repressor, N-terminal DNA binding domain Bac_DNA_binding PF00216.21 AAZ34898.1 - 9.6e-26 89.8 0.1 1.1e-25 89.7 0.1 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 AAZ34898.1 - 2.1e-05 24.6 0.0 2.3e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_bac_2 PF18175.1 AAZ34898.1 - 6.3e-05 22.8 0.0 0.00012 21.9 0.0 1.3 1 0 0 1 1 1 1 CCDC81-like prokaryotic HU domain 2 HU-CCDC81_euk_2 PF18289.1 AAZ34898.1 - 0.00069 19.7 0.0 0.0011 19.1 0.0 1.2 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 NTS PF15447.6 AAZ34898.1 - 0.083 13.4 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 N-terminal segments of PfEMP1 HTH_IclR PF09339.10 AAZ34898.1 - 0.15 11.9 0.1 0.32 10.8 0.0 1.6 2 0 0 2 2 2 0 IclR helix-turn-helix domain SSPI PF14098.6 AAZ34898.1 - 0.18 12.0 1.0 0.44 10.7 0.2 1.9 1 1 1 2 2 2 0 Small, acid-soluble spore protein I DUF2292 PF10055.9 AAZ34899.1 - 1.9e-16 59.4 0.7 2.3e-16 59.2 0.7 1.1 1 0 0 1 1 1 1 Uncharacterized small protein (DUF2292) RACo_linker PF17650.1 AAZ34899.1 - 0.026 14.4 0.0 0.028 14.3 0.0 1.1 1 0 0 1 1 1 0 RACo linker region ABC_tran PF00005.27 AAZ34900.1 - 4.8e-25 88.7 0.0 7e-25 88.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter CysA_C_terminal PF17850.1 AAZ34900.1 - 0.00024 21.6 2.0 0.0092 16.5 0.2 3.9 5 0 0 5 5 5 1 CysA C-terminal regulatory domain AAA_21 PF13304.6 AAZ34900.1 - 0.00035 20.5 0.2 0.071 12.9 0.1 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system TOBE_2 PF08402.10 AAZ34900.1 - 0.00052 20.1 0.0 0.0013 18.8 0.0 1.7 1 0 0 1 1 1 1 TOBE domain OB_MalK PF17912.1 AAZ34900.1 - 0.015 16.1 0.1 0.054 14.3 0.1 2.0 1 0 0 1 1 1 0 MalK OB fold domain SMC_N PF02463.19 AAZ34900.1 - 0.031 13.7 0.1 0.22 10.9 0.1 2.0 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain DUF2384 PF09722.10 AAZ34901.1 - 3.7e-05 23.7 0.0 7.4e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2384) HXXSHH PF07586.11 AAZ34901.1 - 0.19 11.2 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) HlyD_3 PF13437.6 AAZ34902.1 - 7.1e-16 58.8 4.7 1.6e-10 41.6 0.0 3.3 2 1 0 3 3 3 2 HlyD family secretion protein HlyD_D23 PF16576.5 AAZ34902.1 - 2.3e-15 56.4 2.5 3.9e-15 55.6 2.5 1.3 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 AAZ34902.1 - 2.6e-14 52.8 8.7 6.1e-14 51.6 2.3 3.5 3 0 0 3 3 3 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AAZ34902.1 - 0.00023 20.9 0.1 0.0025 17.6 0.1 2.5 2 0 0 2 2 2 1 Biotin-requiring enzyme RnfC_N PF13375.6 AAZ34902.1 - 0.0076 16.2 0.6 3 7.9 0.0 3.2 3 0 0 3 3 3 1 RnfC Barrel sandwich hybrid domain PTS_EIIA_1 PF00358.20 AAZ34902.1 - 0.028 14.2 0.0 0.097 12.4 0.0 1.9 2 0 0 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Peptidase_M23 PF01551.22 AAZ34902.1 - 0.034 14.4 0.4 0.36 11.1 0.0 2.6 3 0 0 3 3 3 0 Peptidase family M23 SurA_N_3 PF13624.6 AAZ34902.1 - 0.28 11.0 7.9 0.58 9.9 6.4 2.4 2 1 0 2 2 2 0 SurA N-terminal domain Plasmid_RAQPRD PF09686.10 AAZ34902.1 - 3.7 7.8 9.6 2.9 8.2 6.5 2.4 2 1 1 3 3 3 0 Plasmid protein of unknown function (Plasmid_RAQPRD) HMGL-like PF00682.19 AAZ34903.1 - 1.5e-39 136.2 1.1 3e-39 135.2 1.1 1.5 1 1 0 1 1 1 1 HMGL-like HMGL-like PF00682.19 AAZ34905.1 - 1.2e-53 182.4 0.0 1.3e-53 182.3 0.0 1.0 1 0 0 1 1 1 1 HMGL-like Peptidase_M41 PF01434.18 AAZ34906.1 - 1e-72 244.0 0.0 1.7e-72 243.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 AAZ34906.1 - 2e-46 157.7 0.1 5.1e-46 156.4 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.15 AAZ34906.1 - 1.5e-12 47.8 1.4 4.6e-12 46.3 0.2 2.1 2 0 0 2 2 2 1 FtsH Extracellular AAA_lid_3 PF17862.1 AAZ34906.1 - 9.9e-12 44.5 0.0 2e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain TIP49 PF06068.13 AAZ34906.1 - 3.6e-06 26.4 0.5 8.2e-06 25.2 0.0 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_5 PF07728.14 AAZ34906.1 - 8.4e-06 25.8 0.0 4.7e-05 23.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 AAZ34906.1 - 0.00034 20.4 0.0 0.0023 17.7 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 AAZ34906.1 - 0.0026 18.1 0.4 0.078 13.4 0.1 2.4 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 AAZ34906.1 - 0.0057 16.9 0.1 0.41 10.9 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.14 AAZ34906.1 - 0.0058 16.8 0.0 0.019 15.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 AAZ34906.1 - 0.006 16.0 0.2 0.013 14.9 0.2 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 AAZ34906.1 - 0.0079 16.4 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 AAZ34906.1 - 0.014 15.1 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 AAZ34906.1 - 0.062 12.8 0.2 0.19 11.2 0.2 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 AAZ34906.1 - 0.11 12.1 0.0 0.36 10.5 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_17 PF13207.6 AAZ34906.1 - 0.12 12.8 0.0 0.38 11.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AAZ34906.1 - 0.16 11.7 0.1 0.58 9.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain GSHPx PF00255.19 AAZ34907.1 - 7e-39 131.7 0.0 8.5e-39 131.5 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 AAZ34907.1 - 0.00028 20.8 0.0 0.00043 20.2 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AAZ34907.1 - 0.00033 20.4 0.0 0.00052 19.7 0.0 1.3 1 0 0 1 1 1 1 Redoxin PQQ PF01011.21 AAZ34908.1 - 9.4e-34 113.8 3.9 3.8e-07 29.7 0.2 8.4 8 0 0 8 8 8 6 PQQ enzyme repeat PQQ_2 PF13360.6 AAZ34908.1 - 9.3e-18 64.7 1.7 9.4e-12 45.0 2.6 3.7 2 1 1 3 3 3 3 PQQ-like domain PQQ_3 PF13570.6 AAZ34908.1 - 1.7e-09 37.9 17.3 0.12 12.9 0.0 8.1 8 0 0 8 8 8 4 PQQ-like domain PseudoU_synth_2 PF00849.22 AAZ34909.1 - 1.3e-13 51.4 0.0 2.6e-13 50.3 0.0 1.5 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 AAZ34909.1 - 1.2e-10 41.0 1.8 2.6e-10 39.8 0.4 2.2 1 1 1 2 2 2 1 S4 domain Formyl_trans_N PF00551.19 AAZ34910.1 - 9.8e-37 126.4 0.0 1.2e-36 126.1 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase DUF489 PF04356.12 AAZ34912.1 - 1.6e-69 233.8 0.5 1.8e-69 233.6 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF489) HTH_38 PF13936.6 AAZ34912.1 - 0.074 12.8 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain MFS_1 PF07690.16 AAZ34913.1 - 6.7e-38 130.5 51.6 6e-37 127.4 40.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DegT_DnrJ_EryC1 PF01041.17 AAZ34914.1 - 1.4e-85 287.8 0.0 1.6e-85 287.6 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 AAZ34914.1 - 3.6e-06 26.5 0.0 7.3e-06 25.5 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 AAZ34914.1 - 0.0037 16.3 0.1 0.0058 15.6 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 AAZ34914.1 - 0.013 14.7 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II ABC_tran PF00005.27 AAZ34915.1 - 5.8e-31 107.8 0.0 1.2e-30 106.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAZ34915.1 - 3.4e-14 53.4 3.9 3.2e-10 40.3 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AAZ34915.1 - 1.3e-06 28.4 0.0 0.045 13.5 0.0 2.2 1 1 1 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 AAZ34915.1 - 0.0012 18.3 0.1 0.82 9.1 0.2 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAZ34915.1 - 0.0014 18.3 0.3 0.0031 17.2 0.3 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AAZ34915.1 - 0.0023 18.4 0.6 0.004 17.7 0.1 1.7 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 AAZ34915.1 - 0.01 15.5 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_30 PF13604.6 AAZ34915.1 - 0.018 14.8 0.0 0.05 13.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_27 PF13514.6 AAZ34915.1 - 0.033 13.8 0.1 0.052 13.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain DUF4162 PF13732.6 AAZ34915.1 - 0.036 14.8 0.0 0.11 13.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) AAA_22 PF13401.6 AAZ34915.1 - 0.14 12.4 0.9 18 5.6 0.1 2.8 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 AAZ34916.1 - 7.7e-48 162.5 0.0 4.1e-23 82.4 0.0 3.2 3 0 0 3 3 3 2 ABC transporter ABC_tran_CTD PF16326.5 AAZ34916.1 - 4.4e-20 71.7 7.6 4.4e-20 71.7 7.6 2.1 2 0 0 2 2 1 1 ABC transporter C-terminal domain AAA_21 PF13304.6 AAZ34916.1 - 2.1e-15 57.3 10.0 0.00011 22.1 0.1 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 AAZ34916.1 - 1.6e-10 40.9 2.1 1.7e-08 34.4 0.1 3.0 3 0 0 3 3 3 1 ABC transporter SMC_N PF02463.19 AAZ34916.1 - 1.3e-07 31.3 2.3 0.0076 15.7 0.1 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAZ34916.1 - 9.3e-06 25.3 0.2 0.04 13.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 AAZ34916.1 - 7.2e-05 22.6 0.0 0.31 10.8 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.6 AAZ34916.1 - 0.00012 22.6 9.9 0.001 19.5 0.1 3.2 4 1 0 4 4 3 2 AAA ATPase domain AAA_15 PF13175.6 AAZ34916.1 - 0.00017 21.4 0.1 0.28 10.9 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_24 PF13479.6 AAZ34916.1 - 0.00018 21.3 0.0 0.34 10.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 AAZ34916.1 - 0.00043 20.9 3.3 2.6 8.5 0.1 3.5 3 0 0 3 3 3 2 AAA domain MeaB PF03308.16 AAZ34916.1 - 0.00049 19.2 0.8 0.13 11.2 0.1 2.6 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 AAZ34916.1 - 0.0014 18.2 0.2 0.77 9.2 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region TrwB_AAD_bind PF10412.9 AAZ34916.1 - 0.0015 17.5 0.4 0.24 10.3 0.1 2.5 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain RsgA_GTPase PF03193.16 AAZ34916.1 - 0.0022 17.9 0.1 2.5 8.0 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 AAZ34916.1 - 0.003 17.6 0.1 4.1 7.5 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase NACHT PF05729.12 AAZ34916.1 - 0.0043 17.0 0.3 1.5 8.8 0.0 2.8 2 0 0 2 2 2 1 NACHT domain ATP-synt_ab PF00006.25 AAZ34916.1 - 0.0055 16.4 0.2 0.72 9.5 0.0 2.4 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.29 AAZ34916.1 - 0.0058 17.1 0.3 2.3 8.6 0.0 3.2 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 AAZ34916.1 - 0.0094 16.2 3.4 0.49 10.6 0.0 3.3 4 0 0 4 4 2 1 AAA domain DUF815 PF05673.13 AAZ34916.1 - 0.011 14.9 0.2 4.3 6.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 AAZ34916.1 - 0.014 15.7 8.4 0.54 10.5 0.3 4.3 4 1 0 4 4 3 0 AAA domain MobB PF03205.14 AAZ34916.1 - 0.015 15.2 0.5 0.2 11.5 0.1 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Roc PF08477.13 AAZ34916.1 - 0.015 15.5 0.9 4.2 7.6 0.0 2.8 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 AAZ34916.1 - 0.024 15.0 0.0 6.6 7.2 0.0 2.5 2 0 0 2 2 2 0 RNA helicase FapA PF03961.13 AAZ34916.1 - 0.028 13.0 0.5 0.053 12.1 0.1 1.6 2 0 0 2 2 2 0 Flagellar Assembly Protein A DUF87 PF01935.17 AAZ34916.1 - 0.03 14.4 0.1 6.7 6.7 0.0 3.6 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_5 PF07728.14 AAZ34916.1 - 0.032 14.2 4.4 6.5 6.8 0.3 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_13 PF13166.6 AAZ34916.1 - 0.036 12.7 3.5 5.6 5.5 0.1 3.1 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 AAZ34916.1 - 0.053 13.1 4.3 13 5.3 0.1 4.6 4 1 1 5 5 5 0 AAA domain AAA_18 PF13238.6 AAZ34916.1 - 0.067 13.7 2.6 3 8.4 0.0 3.5 4 0 0 4 4 3 0 AAA domain IstB_IS21 PF01695.17 AAZ34916.1 - 0.074 12.8 0.5 6.2 6.5 0.0 3.1 4 0 0 4 4 2 0 IstB-like ATP binding protein AAA_19 PF13245.6 AAZ34916.1 - 0.16 12.3 2.2 4 7.7 0.7 3.0 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 AAZ34916.1 - 0.18 11.7 3.1 1.6 8.6 0.3 3.2 3 0 0 3 3 3 0 NTPase Zeta_toxin PF06414.12 AAZ34916.1 - 0.19 11.0 0.7 2 7.7 0.0 2.6 3 0 0 3 3 2 0 Zeta toxin AAA_33 PF13671.6 AAZ34916.1 - 2.5 8.3 6.0 2.8 8.1 0.0 3.5 4 0 0 4 4 3 0 AAA domain MFS_1 PF07690.16 AAZ34917.1 - 1.2e-45 156.0 39.7 1.2e-45 156.0 39.7 1.7 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 AAZ34917.1 - 6e-11 41.9 22.3 2.7e-09 36.4 5.4 2.5 1 1 1 2 2 2 2 Sugar (and other) transporter OATP PF03137.20 AAZ34917.1 - 3.6e-07 28.9 15.0 0.0001 20.8 7.5 3.9 1 1 2 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_4 PF06779.14 AAZ34917.1 - 1.7e-06 27.6 24.0 2.4e-06 27.1 24.0 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Pyr_redox_2 PF07992.14 AAZ34919.1 - 3.4e-62 210.3 0.0 4.1e-62 210.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 AAZ34919.1 - 7.4e-28 97.0 0.6 5e-27 94.3 0.4 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 AAZ34919.1 - 1.3e-20 73.7 0.3 3.9e-17 62.6 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AAZ34919.1 - 3.8e-10 39.7 0.1 5.3e-10 39.2 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 AAZ34919.1 - 1.6e-09 37.5 0.1 2.2e-06 27.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 AAZ34919.1 - 1.6e-08 34.1 0.0 0.0049 16.2 0.0 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 AAZ34919.1 - 1.6e-07 30.7 0.2 3.5e-05 23.1 0.0 3.1 4 0 0 4 4 4 1 Glucose inhibited division protein A HI0933_like PF03486.14 AAZ34919.1 - 1e-06 27.8 1.8 0.00011 21.0 0.7 2.6 3 0 0 3 3 3 2 HI0933-like protein 3HCDH_N PF02737.18 AAZ34919.1 - 1.1e-06 28.7 0.1 0.027 14.3 0.2 2.4 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 AAZ34919.1 - 2.2e-06 27.8 0.5 6.9e-05 23.0 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 AAZ34919.1 - 1.6e-05 24.2 4.0 3.9e-05 22.9 1.6 2.3 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 AAZ34919.1 - 0.0016 17.7 0.1 0.0033 16.7 0.1 1.5 1 0 0 1 1 1 1 Thi4 family 2-Hacid_dh_C PF02826.19 AAZ34919.1 - 0.0036 16.7 0.0 0.47 9.8 0.0 2.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.6 AAZ34919.1 - 0.0063 17.0 0.0 1.1 9.8 0.0 2.3 2 0 0 2 2 2 1 XdhC Rossmann domain DAO PF01266.24 AAZ34919.1 - 0.012 15.2 0.2 0.012 15.2 0.2 2.4 3 1 0 3 3 3 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 AAZ34919.1 - 0.021 14.1 2.2 0.1 11.8 0.2 2.5 2 1 1 3 3 3 0 FAD binding domain K_oxygenase PF13434.6 AAZ34919.1 - 0.043 13.0 0.0 0.086 12.0 0.0 1.5 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) ABC1 PF03109.16 AAZ34920.1 - 1e-33 116.0 0.0 1.9e-33 115.1 0.0 1.5 1 0 0 1 1 1 1 ABC1 family LysE PF01810.18 AAZ34921.1 - 1.4e-30 106.2 12.9 1.6e-30 106.0 12.9 1.0 1 0 0 1 1 1 1 LysE type translocator Peptidase_M23_N PF18421.1 AAZ34922.1 - 2.9e-29 100.8 0.7 5.8e-29 99.8 0.7 1.5 1 0 0 1 1 1 1 Peptidase family M23 N-terminal domain Peptidase_M23 PF01551.22 AAZ34922.1 - 1.1e-27 96.0 0.0 2.6e-27 94.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M23 HATPase_c PF02518.26 AAZ34923.1 - 9.5e-17 61.5 0.0 1.7e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAZ34923.1 - 1.4e-11 44.2 3.8 1.7e-11 44.0 0.7 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 AAZ34923.1 - 2.4e-08 33.8 0.0 7.7e-08 32.2 0.0 1.9 1 0 0 1 1 1 1 PAS domain HATPase_c_3 PF13589.6 AAZ34923.1 - 4.7e-07 29.7 0.0 9.3e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.25 AAZ34923.1 - 5.9e-05 23.0 0.0 0.00015 21.7 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AAZ34923.1 - 0.0063 16.7 0.0 0.022 15.0 0.0 2.0 1 1 0 1 1 1 1 PAS fold HATPase_c_2 PF13581.6 AAZ34923.1 - 0.043 13.8 0.0 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain AAA_16 PF13191.6 AAZ34923.1 - 0.046 14.1 5.3 0.068 13.5 0.5 2.4 2 0 0 2 2 2 0 AAA ATPase domain Med21 PF11221.8 AAZ34923.1 - 0.057 13.7 0.6 0.057 13.7 0.6 2.1 2 1 0 2 2 2 0 Subunit 21 of Mediator complex Adeno_E1B_19K PF01691.16 AAZ34923.1 - 0.1 12.1 0.1 0.24 10.9 0.1 1.5 1 0 0 1 1 1 0 Adenovirus E1B 19K protein / small t-antigen Hpt PF01627.23 AAZ34923.1 - 2.7 8.3 8.6 0.75 10.1 0.7 3.2 2 1 0 2 2 2 0 Hpt domain MAF_flag10 PF01973.18 AAZ34924.1 - 5.3e-05 23.0 0.0 0.047 13.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function DUF115 ZnuA PF01297.17 AAZ34925.1 - 2.5e-57 194.2 0.0 2.8e-57 194.1 0.0 1.0 1 0 0 1 1 1 1 Zinc-uptake complex component A periplasmic MCPsignal PF00015.21 AAZ34926.1 - 1.4e-38 132.4 24.2 1.4e-38 132.4 24.2 3.3 2 1 1 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain 4HB_MCP_1 PF12729.7 AAZ34926.1 - 1.7e-19 70.1 0.5 1.7e-19 70.1 0.5 3.4 3 2 0 4 4 4 1 Four helix bundle sensory module for signal transduction TarH PF02203.15 AAZ34926.1 - 5e-08 33.1 1.0 5e-08 33.1 1.0 3.8 4 1 1 5 5 5 1 Tar ligand binding domain homologue HAMP PF00672.25 AAZ34926.1 - 0.00031 21.1 11.0 0.00051 20.4 0.5 4.8 4 0 0 4 4 4 1 HAMP domain TniB PF05621.11 AAZ34926.1 - 0.029 13.8 0.2 0.064 12.7 0.2 1.7 1 0 0 1 1 1 0 Bacterial TniB protein LysR_substrate PF03466.20 AAZ34927.1 - 5.9e-23 81.3 0.1 8.1e-23 80.9 0.1 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ34927.1 - 3.3e-19 68.6 1.4 6e-19 67.7 1.4 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family SlyX PF04102.12 AAZ34928.1 - 9.1e-23 80.7 3.2 1e-22 80.5 3.2 1.0 1 0 0 1 1 1 1 SlyX MscS_porin PF12795.7 AAZ34928.1 - 0.0023 17.5 0.5 0.0025 17.4 0.5 1.0 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain PKcGMP_CC PF16808.5 AAZ34928.1 - 0.0057 16.5 0.6 0.01 15.7 0.1 1.7 2 0 0 2 2 2 1 Coiled-coil N-terminus of cGMP-dependent protein kinase Nsp1_C PF05064.13 AAZ34928.1 - 0.0067 16.2 0.5 0.008 16.0 0.5 1.2 1 0 0 1 1 1 1 Nsp1-like C-terminal region KASH_CCD PF14662.6 AAZ34928.1 - 0.0067 16.3 2.2 0.0073 16.2 2.2 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH HBM PF16591.5 AAZ34928.1 - 0.0067 15.9 1.8 0.0071 15.8 1.8 1.0 1 0 0 1 1 1 1 Helical bimodular sensor domain HIP1_clath_bdg PF16515.5 AAZ34928.1 - 0.0081 16.7 2.9 0.0088 16.6 2.9 1.0 1 0 0 1 1 1 1 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF2968 PF11180.8 AAZ34928.1 - 0.0086 15.7 2.6 0.0093 15.6 2.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) DUF1635 PF07795.11 AAZ34928.1 - 0.0091 15.9 0.7 0.0092 15.9 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1635) ABC_tran_CTD PF16326.5 AAZ34928.1 - 0.0097 16.1 4.4 0.15 12.3 0.6 2.1 1 1 1 2 2 2 1 ABC transporter C-terminal domain Fib_alpha PF08702.10 AAZ34928.1 - 0.011 15.9 1.4 0.013 15.7 1.4 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family ADIP PF11559.8 AAZ34928.1 - 0.014 15.5 1.1 0.014 15.5 1.1 1.0 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF3347 PF11827.8 AAZ34928.1 - 0.025 14.7 0.4 0.026 14.7 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) CEP63 PF17045.5 AAZ34928.1 - 0.028 14.3 2.7 0.029 14.3 2.7 1.0 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa DUF16 PF01519.16 AAZ34928.1 - 0.042 14.3 2.4 0.046 14.2 2.4 1.0 1 0 0 1 1 1 0 Protein of unknown function DUF16 USP8_interact PF08941.10 AAZ34928.1 - 0.17 11.7 1.8 0.19 11.5 1.8 1.0 1 0 0 1 1 1 0 USP8 interacting GDPD PF03009.17 AAZ34929.1 - 2.6e-12 47.0 0.0 3.6e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family SnoaL PF07366.12 AAZ34930.1 - 1.3e-36 125.2 0.0 1.4e-36 125.0 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 AAZ34930.1 - 4.5e-11 43.3 0.1 8.2e-11 42.5 0.0 1.4 2 0 0 2 2 2 1 SnoaL-like domain Ral PF11058.8 AAZ34930.1 - 0.12 11.9 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Antirestriction protein Ral Epimerase PF01370.21 AAZ34931.1 - 1.3e-08 34.6 0.0 1.4e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 AAZ34931.1 - 5.1e-08 33.0 0.2 5.7e-08 32.9 0.2 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 AAZ34931.1 - 2.6e-05 23.9 0.1 2.7e-05 23.9 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 AAZ34931.1 - 0.00012 21.6 0.0 0.00017 21.1 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 AAZ34931.1 - 0.00055 19.1 0.1 0.00082 18.6 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 AAZ34931.1 - 0.00068 19.1 0.2 0.00095 18.7 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase THF_DHG_CYH_C PF02882.19 AAZ34931.1 - 0.00077 18.8 0.1 0.00095 18.5 0.1 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain F420_oxidored PF03807.17 AAZ34931.1 - 0.0028 18.2 0.1 0.0045 17.5 0.1 1.4 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.20 AAZ34931.1 - 0.013 15.6 0.1 0.018 15.1 0.1 1.2 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.18 AAZ34931.1 - 0.015 15.5 0.4 0.021 15.1 0.4 1.2 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_2 PF03446.15 AAZ34931.1 - 0.016 15.4 0.0 0.021 15.0 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3Beta_HSD PF01073.19 AAZ34931.1 - 0.031 13.3 0.0 0.035 13.1 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 AAZ34931.1 - 0.039 14.4 0.7 0.13 12.7 0.7 2.0 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 AAZ34931.1 - 0.062 13.4 0.3 0.078 13.1 0.3 1.4 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 AAZ34931.1 - 0.068 13.1 0.4 0.089 12.8 0.4 1.3 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Polysacc_synt_2 PF02719.15 AAZ34931.1 - 0.082 12.0 0.3 0.28 10.3 0.3 1.8 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein 2-Hacid_dh_C PF02826.19 AAZ34931.1 - 0.11 11.9 0.4 0.42 9.9 0.1 1.8 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Toprim PF01751.22 AAZ34932.1 - 1.3e-17 63.9 0.0 2.4e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Toprim domain Helicase_C PF00271.31 AAZ34932.1 - 2.1e-05 24.8 0.0 6.7e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Toprim_4 PF13662.6 AAZ34932.1 - 0.011 16.1 0.0 0.032 14.7 0.0 1.7 1 0 0 1 1 1 0 Toprim domain Toprim_2 PF13155.6 AAZ34932.1 - 0.033 14.6 0.0 0.15 12.5 0.0 2.0 2 0 0 2 2 2 0 Toprim-like EAL PF00563.20 AAZ34933.1 - 9.5e-48 162.8 0.0 1.2e-47 162.4 0.0 1.1 1 0 0 1 1 1 1 EAL domain SecE PF00584.20 AAZ34934.1 - 3e-21 75.1 4.3 3e-21 75.1 4.3 2.6 3 0 0 3 3 3 1 SecE/Sec61-gamma subunits of protein translocation complex VIT1 PF01988.19 AAZ34934.1 - 0.032 14.1 0.8 0.032 14.1 0.8 2.0 2 0 0 2 2 2 0 VIT family DUF1616 PF07760.11 AAZ34934.1 - 0.064 12.6 4.9 0.081 12.3 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) Ac76 PF05814.11 AAZ34934.1 - 0.26 11.3 3.6 0.34 11.0 0.9 2.1 2 0 0 2 2 2 0 Orf76 (Ac76) DUF4271 PF14093.6 AAZ34934.1 - 0.55 10.1 5.1 0.76 9.6 1.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4271) DUF4231 PF14015.6 AAZ34934.1 - 1.9 9.0 6.4 8.4 6.9 3.1 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF4231) DUF4366 PF14283.6 AAZ34934.1 - 2.2 8.3 3.9 65 3.5 0.1 2.9 1 1 3 4 4 4 0 Domain of unknown function (DUF4366) DUF983 PF06170.12 AAZ34934.1 - 2.8 8.4 9.7 2.4 8.6 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF983) DUF3043 PF11241.8 AAZ34934.1 - 7.1 6.6 8.7 0.93 9.5 1.6 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF3043) DUF4191 PF13829.6 AAZ34934.1 - 9.8 5.4 12.6 4.1 6.7 1.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4191) TerD PF02342.18 AAZ34935.1 - 2.7e-81 271.6 0.0 3e-81 271.4 0.0 1.0 1 0 0 1 1 1 1 TerD domain AMP-binding PF00501.28 AAZ34936.1 - 5.6e-67 226.2 0.0 7.2e-67 225.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAZ34936.1 - 2.9e-10 41.0 0.0 6.9e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain adh_short_C2 PF13561.6 AAZ34937.1 - 1e-64 218.3 0.0 1.3e-64 218.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAZ34937.1 - 4.3e-53 179.7 0.0 5e-53 179.5 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAZ34937.1 - 8.2e-09 35.6 0.0 1.1e-08 35.2 0.0 1.1 1 0 0 1 1 1 1 KR domain EamA PF00892.20 AAZ34938.1 - 8.3e-27 94.0 34.4 2.5e-13 50.4 8.8 2.0 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 AAZ34938.1 - 0.00032 20.1 1.2 0.00032 20.1 1.2 1.7 1 1 1 2 2 2 1 Triose-phosphate Transporter family DuoxA PF10204.9 AAZ34938.1 - 1.6 7.7 10.2 0.034 13.2 1.7 2.2 2 0 0 2 2 2 0 Dual oxidase maturation factor Transposase_mut PF00872.18 AAZ34939.1 - 2.5e-116 388.7 0.0 3.1e-116 388.4 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ34939.1 - 7.7e-05 23.0 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain DUF4844 PF16133.5 AAZ34939.1 - 0.22 12.1 0.0 0.55 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) PmbA_TldD PF01523.16 AAZ34942.1 - 3.3e-20 73.1 0.0 5.2e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 Putative modulator of DNA gyrase COG6 PF06419.11 AAZ34942.1 - 0.098 10.9 0.0 0.42 8.8 0.1 1.8 2 0 0 2 2 2 0 Conserved oligomeric complex COG6 ATPgrasp_ST PF14397.6 AAZ34944.1 - 3.1e-104 348.3 0.0 3.5e-104 348.1 0.0 1.0 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp RimK PF08443.11 AAZ34944.1 - 1e-09 38.3 0.0 1.5e-05 24.6 0.0 3.1 3 0 0 3 3 3 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 AAZ34944.1 - 9e-09 35.6 0.0 0.0043 17.1 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_YheCD PF14398.6 AAZ34944.1 - 3.8e-08 32.9 0.0 0.0075 15.5 0.0 2.4 3 0 0 3 3 3 2 YheC/D like ATP-grasp GSH-S_ATP PF02955.16 AAZ34944.1 - 2.8e-06 26.8 0.0 0.032 13.6 0.0 2.4 2 0 0 2 2 2 2 Prokaryotic glutathione synthetase, ATP-grasp domain TTL PF03133.15 AAZ34944.1 - 0.0049 16.0 0.0 0.052 12.7 0.0 2.0 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_Ter PF15632.6 AAZ34944.1 - 0.035 13.9 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon ATPgrasp_TupA PF14305.6 AAZ34944.1 - 0.11 12.3 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 TupA-like ATPgrasp Aminotran_1_2 PF00155.21 AAZ34945.1 - 1.6e-26 93.4 0.0 2e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II AAA_21 PF13304.6 AAZ34947.1 - 2.5e-21 76.8 1.2 4.1e-18 66.2 1.2 2.3 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AAZ34947.1 - 3.4e-19 69.8 0.1 4.9e-13 49.5 0.0 2.2 1 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 AAZ34947.1 - 0.00046 20.1 0.0 0.00085 19.3 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 AAZ34947.1 - 0.0014 19.2 0.0 0.0028 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAZ34947.1 - 0.0016 18.1 0.0 0.0045 16.7 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 AAZ34947.1 - 0.0021 17.5 0.1 0.027 13.9 0.1 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain ABC_tran PF00005.27 AAZ34947.1 - 0.0041 17.6 0.1 0.0093 16.5 0.1 1.5 1 1 0 1 1 1 1 ABC transporter AAA_13 PF13166.6 AAZ34947.1 - 0.13 10.8 0.1 0.6 8.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain Acetyltransf_10 PF13673.7 AAZ34948.1 - 1.4e-08 34.8 0.0 1.6e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAZ34948.1 - 8e-08 32.5 0.0 1e-07 32.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAZ34948.1 - 1.9e-06 28.2 0.0 2.6e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Condensation PF00668.20 AAZ34950.1 - 5.3e-106 355.0 0.0 7.7e-106 354.5 0.0 1.2 1 0 0 1 1 1 1 Condensation domain AMP-binding PF00501.28 AAZ34950.1 - 8e-91 304.7 0.0 1.1e-90 304.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 AAZ34950.1 - 5e-15 55.6 0.4 1.1e-13 51.3 0.1 2.6 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 AAZ34950.1 - 7.6e-13 49.3 0.0 1.9e-12 48.0 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF3925 PF13063.6 AAZ34951.1 - 0.2 11.9 0.8 0.27 11.5 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3925) Gram_pos_anchor PF00746.21 AAZ34951.1 - 2.1 8.4 6.0 0.23 11.4 0.6 2.0 2 0 0 2 2 2 0 LPXTG cell wall anchor motif BatD PF13584.6 AAZ34952.1 - 1.5e-103 347.3 0.0 1.8e-103 347.0 0.0 1.1 1 0 0 1 1 1 1 Oxygen tolerance TRAPPC10 PF12584.8 AAZ34952.1 - 0.013 15.2 0.0 2.2 8.0 0.0 2.5 2 0 0 2 2 2 0 Trafficking protein particle complex subunit 10, TRAPPC10 ChapFlgA PF13144.6 AAZ34954.1 - 1.9e-37 128.0 6.6 3.4e-37 127.2 6.6 1.4 1 0 0 1 1 1 1 Chaperone for flagella basal body P-ring formation ChapFlgA_N PF17656.1 AAZ34954.1 - 6.6e-21 74.3 0.1 5.3e-20 71.4 0.0 2.1 2 0 0 2 2 2 1 FlgA N-terminal domain SAF PF08666.12 AAZ34954.1 - 2.6e-09 37.6 0.8 1.1e-08 35.5 0.4 2.2 2 0 0 2 2 2 1 SAF domain PMT_2 PF13231.6 AAZ34955.1 - 3.8e-13 49.9 13.8 3.8e-13 49.9 13.8 3.7 4 1 0 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT PF02366.18 AAZ34955.1 - 2.2e-11 43.8 13.9 2.2e-11 43.8 13.9 2.3 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Acetyltransf_4 PF13420.7 AAZ34956.1 - 8.4e-20 71.5 0.0 9.7e-20 71.3 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAZ34956.1 - 1.3e-11 44.7 0.0 1.7e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 AAZ34956.1 - 1.9e-07 31.8 0.0 2.6e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAZ34956.1 - 2e-05 24.6 0.0 2.7e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAZ34956.1 - 3.7e-05 24.1 0.1 6.9e-05 23.2 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAZ34956.1 - 0.00035 20.5 0.1 0.00082 19.3 0.1 1.6 1 1 0 1 1 1 1 FR47-like protein FGE-sulfatase PF03781.16 AAZ34957.1 - 6e-58 196.5 2.8 6.8e-58 196.3 2.8 1.0 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 Cauli_VI PF01693.16 AAZ34957.1 - 0.23 11.8 1.1 0.73 10.2 0.2 2.3 2 0 0 2 2 2 0 Caulimovirus viroplasmin CBM_14 PF01607.24 AAZ34958.1 - 0.27 11.4 2.8 0.4 10.9 1.7 1.9 1 1 0 1 1 1 0 Chitin binding Peritrophin-A domain ABC_tran PF00005.27 AAZ34959.1 - 3.9e-35 121.3 0.0 6.1e-35 120.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter TOBE_2 PF08402.10 AAZ34959.1 - 1.2e-08 35.0 0.1 3.2e-08 33.6 0.1 1.8 1 0 0 1 1 1 1 TOBE domain AAA_21 PF13304.6 AAZ34959.1 - 0.001 19.0 0.8 0.027 14.3 0.1 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AAZ34959.1 - 0.01 15.6 0.1 0.029 14.1 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AAZ34959.1 - 0.01 15.7 0.1 0.029 14.3 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase DUF2158 PF09926.9 AAZ34959.1 - 0.036 13.8 0.2 0.077 12.7 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized small protein (DUF2158) AAA_16 PF13191.6 AAZ34959.1 - 0.049 14.0 0.1 0.1 13.0 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain MIT_C PF16565.5 AAZ34959.1 - 0.077 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Phospholipase D-like domain at C-terminus of MIT RcpC PF16976.5 AAZ34959.1 - 0.12 12.4 0.7 8.6 6.4 0.1 2.8 3 0 0 3 3 3 0 Flp pilus assembly protein RcpC/CpaB TniB PF05621.11 AAZ34959.1 - 0.15 11.5 1.1 0.75 9.2 0.1 2.3 3 0 0 3 3 3 0 Bacterial TniB protein AAA_28 PF13521.6 AAZ34959.1 - 1.6 9.0 3.3 4.1 7.6 0.5 2.4 2 1 0 2 2 2 0 AAA domain GrpE PF01025.19 AAZ34960.1 - 3.4e-50 170.0 1.2 4e-50 169.7 1.2 1.0 1 0 0 1 1 1 1 GrpE Tropomyosin_1 PF12718.7 AAZ34960.1 - 0.087 13.0 4.7 0.17 12.1 4.7 1.4 1 0 0 1 1 1 0 Tropomyosin like CLZ PF16526.5 AAZ34960.1 - 8.6 6.8 7.4 5 7.6 4.3 2.0 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels MFS_1 PF07690.16 AAZ34961.1 - 5e-48 163.8 97.3 1.5e-40 139.2 52.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AAZ34961.1 - 1.4e-17 63.7 34.3 9.2e-14 51.1 8.7 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 AAZ34961.1 - 0.00039 19.4 2.1 0.00039 19.4 2.1 3.1 1 1 2 3 3 3 3 MFS_1 like family DUF2854 PF11016.8 AAZ34961.1 - 0.16 11.8 0.1 0.38 10.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) DUF4946 PF16304.5 AAZ34962.1 - 1.5e-68 229.3 0.3 2.1e-68 228.8 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4946) Thymidylat_synt PF00303.19 AAZ34963.1 - 3.3e-87 292.0 0.0 3.8e-87 291.8 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Cupin_7 PF12973.7 AAZ34964.1 - 2.6e-10 40.1 0.0 4.6e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 ChrR Cupin-like domain zf-HC2 PF13490.6 AAZ34964.1 - 0.0073 16.5 0.6 0.032 14.5 0.4 2.2 2 0 0 2 2 2 1 Putative zinc-finger Cupin_2 PF07883.11 AAZ34964.1 - 0.0085 15.8 0.1 0.018 14.8 0.1 1.5 1 0 0 1 1 1 1 Cupin domain Auxin_BP PF02041.16 AAZ34964.1 - 0.027 14.1 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 Auxin binding protein E1-E2_ATPase PF00122.20 AAZ34965.1 - 2.6e-44 150.9 0.1 4.9e-44 150.0 0.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 AAZ34965.1 - 3.6e-30 105.8 0.0 6.4e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase ATPase-cat_bd PF12156.8 AAZ34965.1 - 3.3e-27 95.1 0.0 5.1e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 Putative metal-binding domain of cation transport ATPase Hydrolase_3 PF08282.12 AAZ34965.1 - 7.2e-09 35.8 0.1 1.2e-08 35.0 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 AAZ34965.1 - 3.5e-07 30.5 0.0 8.6e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Heavy-metal-associated domain HAD PF12710.7 AAZ34965.1 - 0.00036 21.0 0.0 0.0018 18.7 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase BPD_transp_2 PF02653.16 AAZ34966.1 - 4.3e-37 127.7 36.0 5.6e-37 127.4 36.0 1.1 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component AAA_21 PF13304.6 AAZ34967.1 - 2.5e-18 66.9 0.0 4e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AAZ34967.1 - 2e-06 27.8 0.0 3.3e-06 27.1 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain Amdase PF17645.1 AAZ34967.1 - 0.14 11.8 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Arylmalonate decarboxylase adh_short_C2 PF13561.6 AAZ34968.1 - 1.3e-23 83.8 0.0 1.5e-23 83.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAZ34968.1 - 1.6e-22 80.0 0.0 2e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAZ34968.1 - 0.00013 22.0 0.2 0.00017 21.5 0.2 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 AAZ34968.1 - 0.038 13.4 0.0 0.058 12.8 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 AAZ34968.1 - 0.052 13.1 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family DegT_DnrJ_EryC1 PF01041.17 AAZ34968.1 - 0.056 12.8 0.0 9.5 5.4 0.0 2.7 2 1 1 3 3 3 0 DegT/DnrJ/EryC1/StrS aminotransferase family NAD_binding_10 PF13460.6 AAZ34968.1 - 0.11 12.3 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Bax1-I PF01027.20 AAZ34969.1 - 9.1e-41 140.0 32.8 1e-40 139.8 32.8 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 CcmD PF04995.14 AAZ34969.1 - 0.049 13.7 0.1 0.049 13.7 0.1 2.7 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) Helicase_C_2 PF13307.6 AAZ34970.1 - 1e-34 120.1 0.0 2.6e-33 115.6 0.0 2.2 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD PF00270.29 AAZ34970.1 - 2.5e-05 24.1 0.1 0.00042 20.1 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 AAZ34970.1 - 0.0007 19.6 0.0 0.0083 16.1 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD_2 PF06733.15 AAZ34970.1 - 0.025 14.2 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 DEAD_2 Helicase_C PF00271.31 AAZ34970.1 - 0.049 14.0 0.0 0.097 13.0 0.0 1.5 1 0 0 1 1 1 0 Helicase conserved C-terminal domain 2-oxoacid_dh PF00198.23 AAZ34971.1 - 3e-76 255.9 0.0 4.2e-76 255.5 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 AAZ34971.1 - 3.5e-44 148.5 10.0 2.7e-22 78.4 2.1 2.7 3 0 0 3 3 2 2 Biotin-requiring enzyme E3_binding PF02817.17 AAZ34971.1 - 4.3e-15 55.8 0.0 1.1e-14 54.4 0.0 1.8 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 AAZ34971.1 - 5.5e-13 48.5 8.7 0.0049 16.7 0.1 4.9 3 2 2 5 5 5 4 Biotin-lipoyl like GCV_H PF01597.19 AAZ34971.1 - 2e-08 34.2 3.1 0.00087 19.2 0.3 2.5 2 0 0 2 2 2 2 Glycine cleavage H-protein RnfC_N PF13375.6 AAZ34971.1 - 1.8e-06 27.8 0.8 0.063 13.2 0.0 2.6 2 0 0 2 2 2 2 RnfC Barrel sandwich hybrid domain HlyD_D23 PF16576.5 AAZ34971.1 - 3.6e-06 26.4 0.6 0.15 11.2 0.0 4.1 2 2 2 4 4 4 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion PYNP_C PF07831.13 AAZ34971.1 - 6.6e-06 25.7 2.8 0.73 9.5 0.0 4.2 2 2 2 4 4 4 2 Pyrimidine nucleoside phosphorylase C-terminal domain HlyD_3 PF13437.6 AAZ34971.1 - 3.8e-05 24.3 3.2 0.32 11.7 0.0 4.2 2 2 2 4 4 4 1 HlyD family secretion protein NQRA PF05896.11 AAZ34971.1 - 0.00039 19.9 1.0 0.53 9.7 0.1 2.9 2 1 1 3 3 3 3 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) PTS_EIIA_1 PF00358.20 AAZ34971.1 - 0.0064 16.2 1.3 10 5.9 0.0 3.9 2 2 2 4 4 4 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 DEC-1_N PF04625.13 AAZ34971.1 - 0.05 12.6 24.7 0.34 9.9 7.4 2.5 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region DUF1285 PF06938.11 AAZ34971.1 - 0.2 11.7 0.0 13 5.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1285) CAT PF00302.18 AAZ34971.1 - 0.26 11.2 0.0 0.38 10.7 0.0 1.2 1 0 0 1 1 1 0 Chloramphenicol acetyltransferase DUF4813 PF16072.5 AAZ34971.1 - 1.6 8.3 39.2 3.3 7.3 13.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4813) DUF3597 PF12200.8 AAZ34971.1 - 3.5 8.2 18.1 8.2 7.0 4.9 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) PRCC PF10253.9 AAZ34971.1 - 4 8.2 6.2 12 6.6 0.2 2.2 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting PseudoU_synth_2 PF00849.22 AAZ34972.1 - 1.5e-33 116.2 0.5 2e-33 115.7 0.5 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 AAZ34972.1 - 3.6e-07 29.8 0.8 6.2e-07 29.0 0.1 1.8 2 0 0 2 2 2 1 S4 domain Acyl_transf_3 PF01757.22 AAZ34973.1 - 9e-25 87.4 35.8 1.2e-24 87.1 35.8 1.1 1 0 0 1 1 1 1 Acyltransferase family HHH_3 PF12836.7 AAZ34974.1 - 2.7e-22 78.8 0.5 4.2e-22 78.2 0.5 1.3 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.23 AAZ34974.1 - 1e-07 31.5 0.3 0.005 16.7 0.0 2.8 3 0 0 3 3 3 2 Helix-hairpin-helix motif T2SSK PF03934.13 AAZ34974.1 - 1.3e-05 24.7 0.1 2e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein K HHH_6 PF14579.6 AAZ34974.1 - 0.00019 21.6 0.1 0.00039 20.6 0.0 1.5 1 1 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 AAZ34974.1 - 0.00029 21.4 0.2 1.2 9.8 0.0 2.3 2 0 0 2 2 2 2 Helix-hairpin-helix domain HHH_8 PF14716.6 AAZ34974.1 - 0.026 14.9 0.9 2.1 8.8 0.1 2.2 1 1 1 2 2 2 0 Helix-hairpin-helix domain HHH_2 PF12826.7 AAZ34974.1 - 0.041 14.0 0.1 6.8 6.9 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif FliP PF00813.20 AAZ34975.1 - 4.7e-79 264.7 20.6 7.1e-79 264.1 20.6 1.2 1 0 0 1 1 1 1 FliP family Transposase_mut PF00872.18 AAZ34976.1 - 6.2e-60 203.1 0.0 7.8e-60 202.7 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ34976.1 - 0.00033 21.0 0.0 0.00086 19.7 0.0 1.7 2 0 0 2 2 2 1 MULE transposase domain DUF4844 PF16133.5 AAZ34976.1 - 0.088 13.4 0.0 0.21 12.1 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4844) UPRTase PF14681.6 AAZ34977.1 - 3.8e-62 209.4 0.1 4.3e-62 209.2 0.1 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 AAZ34977.1 - 3.2e-14 52.8 0.4 4.2e-14 52.4 0.4 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.6 AAZ34977.1 - 0.019 15.0 0.1 0.029 14.4 0.1 1.3 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain ABC_tran PF00005.27 AAZ34979.1 - 1.6e-30 106.4 0.0 3.9e-30 105.2 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 AAZ34979.1 - 8.4e-29 101.1 3.2 1.1e-28 100.7 3.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 AAZ34979.1 - 0.00027 20.4 0.3 0.011 15.2 0.5 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 AAZ34979.1 - 0.00095 19.1 0.1 0.0023 17.9 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 AAZ34979.1 - 0.0013 19.1 0.8 0.0056 17.1 0.3 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 AAZ34979.1 - 0.0055 16.4 0.1 0.016 14.9 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.6 AAZ34979.1 - 0.015 15.8 0.6 3.4 8.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 AAZ34979.1 - 0.017 15.4 0.4 0.11 12.8 0.4 2.2 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 AAZ34979.1 - 0.027 14.2 0.0 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_25 PF13481.6 AAZ34979.1 - 0.053 13.1 2.0 0.25 10.9 2.0 2.0 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 AAZ34979.1 - 0.068 13.3 0.1 0.15 12.1 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.6 AAZ34979.1 - 0.073 13.3 1.5 0.15 12.3 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_21 PF13304.6 AAZ34979.1 - 0.083 12.7 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system ATP-synt_ab PF00006.25 AAZ34979.1 - 0.12 12.1 0.0 0.72 9.5 0.0 2.1 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF87 PF01935.17 AAZ34979.1 - 0.12 12.4 1.7 0.14 12.2 0.5 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain HTH_1 PF00126.27 AAZ34980.1 - 7.8e-19 67.4 0.1 1.5e-18 66.5 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 AAZ34980.1 - 9.4e-13 48.0 0.3 2.2e-12 46.8 0.0 1.6 2 0 0 2 2 2 1 LysR substrate binding domain Acyl-CoA_dh_C PF12806.7 AAZ34982.1 - 1e-34 119.4 1.3 2.5e-34 118.1 0.4 2.1 2 0 0 2 2 2 1 Acetyl-CoA dehydrogenase C-terminal like Acyl-CoA_dh_1 PF00441.24 AAZ34982.1 - 8.9e-18 64.9 3.6 1.6e-17 64.1 0.3 2.6 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 AAZ34982.1 - 3.8e-17 62.3 0.0 8.4e-17 61.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain AcylCoA_DH_N PF12418.8 AAZ34982.1 - 2.8e-12 46.4 0.1 6.2e-12 45.3 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase N terminal Acyl-CoA_dh_N PF02771.16 AAZ34982.1 - 3.4e-12 47.0 0.0 9.8e-12 45.5 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain SOXp PF12336.8 AAZ34982.1 - 0.097 13.7 0.1 0.24 12.5 0.1 1.7 1 0 0 1 1 1 0 SOX transcription factor pRN1_helical PF13010.6 AAZ34982.1 - 0.21 11.5 0.0 0.48 10.4 0.0 1.5 1 0 0 1 1 1 0 Primase helical domain T6SS_HCP PF05638.12 AAZ34983.1 - 3.4e-36 124.5 0.2 4e-36 124.3 0.2 1.1 1 0 0 1 1 1 1 Type VI secretion system effector, Hcp Glycos_transf_2 PF00535.26 AAZ34985.1 - 8.3e-45 152.6 0.1 5.5e-23 81.6 0.0 3.2 3 0 0 3 3 3 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAZ34985.1 - 3e-25 89.5 0.7 3.4e-12 46.8 0.0 5.0 6 0 0 6 6 6 2 Glycosyltransferase like family 2 Glyco_trans_1_2 PF13524.6 AAZ34985.1 - 4.6e-07 30.2 0.0 3.4e-06 27.4 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_21 PF13506.6 AAZ34985.1 - 0.0001 21.9 0.0 0.097 12.1 0.1 2.7 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_5 PF13712.6 AAZ34985.1 - 0.00045 20.0 0.0 0.00092 18.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family Glyco_tranf_2_2 PF10111.9 AAZ34985.1 - 0.0008 19.0 0.0 1.2 8.5 0.0 3.7 4 0 0 4 4 4 1 Glycosyltransferase like family 2 Glyco_trans_1_4 PF13692.6 AAZ34985.1 - 0.0029 18.0 0.0 0.012 16.1 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_7C PF02709.14 AAZ34985.1 - 0.079 12.6 0.0 0.24 11.1 0.0 1.8 2 0 0 2 2 2 0 N-terminal domain of galactosyltransferase NTP_transf_3 PF12804.7 AAZ34985.1 - 0.13 12.7 0.5 3.1 8.1 0.0 3.0 3 0 0 3 3 3 0 MobA-like NTP transferase domain MFS_1 PF07690.16 AAZ34986.1 - 6.5e-26 91.1 60.8 2.7e-14 52.9 22.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 AAZ34986.1 - 0.00024 20.6 37.9 0.00051 19.4 37.9 2.2 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 AAZ34986.1 - 0.017 14.0 25.3 0.1 11.4 11.8 2.5 3 0 0 3 3 3 0 Sugar (and other) transporter MFS_2 PF13347.6 AAZ34986.1 - 0.45 9.0 26.2 0.26 9.8 6.3 2.3 2 0 0 2 2 2 0 MFS/sugar transport protein MFS_3 PF05977.13 AAZ34986.1 - 0.67 8.3 30.9 0.21 10.0 3.5 2.3 2 0 0 2 2 2 0 Transmembrane secretion effector MFS_1_like PF12832.7 AAZ34986.1 - 2 7.2 25.5 0.047 12.5 12.5 2.1 2 0 0 2 2 2 0 MFS_1 like family ATP-grasp PF02222.22 AAZ34988.1 - 4.1e-57 192.5 0.0 5.7e-57 192.0 0.0 1.1 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 AAZ34988.1 - 5e-14 51.7 0.0 8.5e-14 51.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain GARS_A PF01071.19 AAZ34988.1 - 0.0046 16.7 0.0 0.0077 16.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 2-Hacid_dh_C PF02826.19 AAZ34988.1 - 0.0069 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Chorismate_synt PF01264.21 AAZ34989.1 - 9.6e-138 458.3 0.0 1.1e-137 458.2 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase DUF1652 PF07865.11 AAZ34990.1 - 1.8e-19 69.3 0.5 2.4e-19 68.9 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1652) CheR PF01739.18 AAZ34991.1 - 1.1e-39 135.9 0.0 1.6e-39 135.5 0.0 1.1 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain CheR_N PF03705.15 AAZ34991.1 - 3e-07 30.1 0.0 5.9e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 CheR methyltransferase, all-alpha domain TPR_17 PF13431.6 AAZ34991.1 - 0.0002 21.5 1.9 0.00035 20.7 0.2 2.4 3 0 0 3 3 2 1 Tetratricopeptide repeat Methyltransf_25 PF13649.6 AAZ34991.1 - 0.00081 20.0 0.0 0.31 11.8 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain TPR_2 PF07719.17 AAZ34991.1 - 0.0096 16.0 9.3 0.1 12.7 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 AAZ34991.1 - 0.01 16.6 14.3 0.22 12.5 0.8 4.1 2 1 1 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 AAZ34991.1 - 0.013 16.1 10.8 0.16 12.7 4.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 AAZ34991.1 - 0.027 15.1 1.3 0.027 15.1 1.3 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat Methyltransf_23 PF13489.6 AAZ34991.1 - 0.036 13.9 0.0 0.072 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 AAZ34991.1 - 0.036 14.8 0.1 3.7 8.4 0.0 2.5 3 0 0 3 3 2 0 Methyltransferase domain TPR_19 PF14559.6 AAZ34991.1 - 0.067 13.7 8.6 0.097 13.2 5.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 AAZ34991.1 - 0.097 12.9 2.9 0.98 9.8 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 AAZ34991.1 - 0.16 11.8 2.6 1.1 9.2 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 AAZ34991.1 - 2.8 8.3 8.5 1.1 9.6 4.2 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat YitT_membrane PF02588.15 AAZ34992.1 - 0.0027 17.1 3.6 0.0031 16.9 0.3 2.2 2 0 0 2 2 2 1 Uncharacterised 5xTM membrane BCR, YitT family COG1284 ICMT PF04140.14 AAZ34992.1 - 0.088 13.2 1.6 0.22 12.0 0.6 2.1 1 1 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family SieB PF14163.6 AAZ34992.1 - 0.89 9.0 4.4 0.25 10.8 0.9 1.9 2 1 0 2 2 2 0 Super-infection exclusion protein B PEMT PF04191.13 AAZ34992.1 - 7.6 7.0 11.8 0.12 12.8 3.2 2.4 2 2 0 2 2 2 0 Phospholipid methyltransferase DUF3455 PF11937.8 AAZ34993.1 - 5.5e-30 104.8 3.9 7.8e-30 104.4 3.1 1.7 2 1 0 2 2 2 1 Protein of unknown function (DUF3455) Transposase_mut PF00872.18 AAZ34994.1 - 2.9e-117 391.8 0.0 3.5e-117 391.5 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ34994.1 - 8e-05 23.0 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain DUF4844 PF16133.5 AAZ34994.1 - 0.23 12.0 0.0 0.55 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) LamB_YcsF PF03746.16 AAZ34995.1 - 3.5e-92 308.4 0.4 4e-92 308.2 0.4 1.0 1 0 0 1 1 1 1 LamB/YcsF family ATP-grasp PF02222.22 AAZ34996.1 - 2.4e-54 183.5 0.0 3.9e-54 182.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 AAZ34996.1 - 9.4e-07 28.6 0.0 3.2e-06 26.8 0.0 1.8 2 1 0 2 2 2 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 AAZ34996.1 - 3.2e-06 26.8 0.0 7.6e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Epimerase PF01370.21 AAZ34996.1 - 1.9e-05 24.3 0.0 3.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ATP-grasp_3 PF02655.14 AAZ34996.1 - 7.1e-05 22.9 0.0 0.00023 21.2 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 AAZ34996.1 - 0.00064 19.5 0.0 0.003 17.3 0.0 1.9 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 2-Hacid_dh_C PF02826.19 AAZ34996.1 - 0.0039 16.6 0.0 0.0072 15.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RimK PF08443.11 AAZ34996.1 - 0.011 15.3 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 RimK-like ATP-grasp domain RmlD_sub_bind PF04321.17 AAZ34996.1 - 0.019 14.1 0.1 0.031 13.4 0.1 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Pyr_redox PF00070.27 AAZ34996.1 - 0.1 13.2 0.4 1.2 9.8 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 AAZ34996.1 - 0.11 12.8 0.2 0.33 11.2 0.1 1.8 1 1 0 1 1 1 0 TrkA-N domain DUF1853 PF08907.11 AAZ34997.1 - 1.2e-100 336.9 7.5 1.4e-100 336.8 7.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1853) Ish1 PF10281.9 AAZ34997.1 - 0.13 12.5 1.8 0.32 11.3 1.8 1.6 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein CbtA PF09490.10 AAZ34998.1 - 7.8e-66 222.3 25.5 9.1e-66 222.1 25.5 1.0 1 0 0 1 1 1 1 Probable cobalt transporter subunit (CbtA) DUF3040 PF11239.8 AAZ34998.1 - 0.0054 17.0 8.6 0.16 12.2 0.3 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF3040) DUF4199 PF13858.6 AAZ34998.1 - 0.024 15.1 3.7 5.6 7.3 0.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF4199) DUF4149 PF13664.6 AAZ34998.1 - 0.067 13.5 12.4 0.74 10.2 3.8 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4149) Ribosomal_S15 PF00312.22 AAZ34999.1 - 5.1e-35 119.5 0.1 5.7e-35 119.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S15 DUF3047 PF11249.8 AAZ34999.1 - 0.16 11.4 0.0 0.21 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3047) MazG-like PF12643.7 AAZ35000.1 - 9.8e-08 32.2 0.1 1.4e-07 31.7 0.1 1.2 1 0 0 1 1 1 1 MazG-like family MazG PF03819.17 AAZ35000.1 - 0.00012 22.2 0.1 0.00017 21.7 0.1 1.3 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain DUF3379 PF11859.8 AAZ35000.1 - 0.02 14.2 0.0 0.02 14.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3379) AI-2E_transport PF01594.16 AAZ35002.1 - 1.1e-56 192.4 33.0 1.2e-56 192.2 33.0 1.0 1 0 0 1 1 1 1 AI-2E family transporter Gemini_mov PF01708.16 AAZ35002.1 - 2.5 7.9 5.2 25 4.7 0.4 2.8 2 0 0 2 2 2 0 Geminivirus putative movement protein PDR_assoc PF08370.11 AAZ35002.1 - 3.9 7.3 7.6 0.13 12.1 1.0 2.1 2 0 0 2 2 2 0 Plant PDR ABC transporter associated MFS_1 PF07690.16 AAZ35003.1 - 1.5e-56 191.8 44.1 2.8e-49 167.9 26.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AAZ35003.1 - 3.2e-08 32.9 38.7 0.0017 17.3 6.7 3.2 2 1 1 3 3 3 3 Sugar (and other) transporter OATP PF03137.20 AAZ35003.1 - 0.00089 17.7 0.4 0.00089 17.7 0.4 3.0 2 2 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family Phage_holin_5_2 PF16079.5 AAZ35003.1 - 6.5 7.2 11.1 13 6.2 0.1 3.7 2 1 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V NAD_binding_9 PF13454.6 AAZ35004.1 - 1.7e-28 99.6 0.1 8.4e-28 97.3 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 AAZ35004.1 - 3.3e-08 33.6 0.8 1.4e-07 31.6 0.0 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AAZ35004.1 - 1.3e-05 24.6 0.0 0.00021 20.6 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AAZ35004.1 - 4.2e-05 23.3 0.3 4.2e-05 23.3 0.3 2.7 2 2 1 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 AAZ35004.1 - 0.00063 19.0 0.0 0.73 8.9 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 AAZ35004.1 - 0.00086 18.5 2.7 0.052 12.6 0.0 3.1 3 1 0 3 3 3 1 FAD binding domain FAD_binding_3 PF01494.19 AAZ35004.1 - 0.005 16.1 1.3 0.013 14.8 0.2 2.0 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 AAZ35004.1 - 0.0061 15.7 0.2 0.093 11.8 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.14 AAZ35004.1 - 0.0081 14.9 0.1 0.025 13.3 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 AAZ35004.1 - 0.014 15.9 0.2 0.14 12.7 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 AAZ35004.1 - 0.022 15.0 0.0 0.14 12.4 0.0 2.3 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox_3 PF13738.6 AAZ35004.1 - 0.041 13.1 0.0 1.4 8.1 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 AAZ35004.1 - 0.091 12.0 0.0 0.2 10.8 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 AAZ35004.1 - 0.094 11.5 0.8 0.15 10.9 0.0 1.7 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.22 AAZ35004.1 - 0.13 11.4 0.0 6 5.8 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Xan_ur_permease PF00860.20 AAZ35005.1 - 2.6e-55 187.7 48.1 3.3e-55 187.4 48.1 1.1 1 0 0 1 1 1 1 Permease family PhzC-PhzF PF02567.16 AAZ35006.1 - 2.5e-55 187.9 0.0 2.8e-55 187.8 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.11 AAZ35006.1 - 0.0011 18.1 0.0 0.0018 17.4 0.0 1.2 1 0 0 1 1 1 1 Proline racemase DUF4880 PF16220.5 AAZ35006.1 - 0.094 12.6 0.3 1.5 8.8 0.1 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4880) SnoaL_2 PF12680.7 AAZ35007.1 - 4.2e-09 37.0 0.0 6.1e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 AAZ35007.1 - 2.5e-05 24.1 0.1 0.0001 22.1 0.1 1.9 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase SoxG PF04268.12 AAZ35008.1 - 3.7e-07 30.4 0.0 5.6e-07 29.8 0.0 1.3 1 1 0 1 1 1 1 Sarcosine oxidase, gamma subunit family GCV_T PF01571.21 AAZ35008.1 - 3.1e-06 26.7 0.0 5.9e-06 25.8 0.0 1.4 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain Amidohydro_2 PF04909.14 AAZ35009.1 - 1.2e-31 110.6 1.3 1.4e-31 110.4 1.3 1.0 1 0 0 1 1 1 1 Amidohydrolase SCFA_trans PF02667.14 AAZ35010.1 - 1.4e-83 281.4 19.2 1.8e-83 281.1 19.2 1.0 1 0 0 1 1 1 1 Short chain fatty acid transporter DcuC PF03606.15 AAZ35010.1 - 9.5e-05 21.0 3.0 9.5e-05 21.0 3.0 2.5 3 0 0 3 3 3 1 C4-dicarboxylate anaerobic carrier Ribosomal_L5_C PF00673.21 AAZ35011.1 - 1.8e-40 137.0 0.0 6.6e-40 135.2 0.0 1.8 2 0 0 2 2 2 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 AAZ35011.1 - 8e-27 93.4 0.5 1.4e-26 92.6 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 TraC PF07820.12 AAZ35011.1 - 0.028 14.7 0.1 0.047 14.0 0.1 1.3 1 0 0 1 1 1 0 TraC-like protein ABC_tran PF00005.27 AAZ35012.1 - 8.6e-26 91.1 0.0 1.5e-25 90.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAZ35012.1 - 2.8e-10 40.5 3.0 1.7e-05 24.8 0.2 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAZ35012.1 - 3.2e-06 26.7 0.0 0.00013 21.5 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAZ35012.1 - 3.5e-06 26.6 0.1 9.3e-06 25.3 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AAZ35012.1 - 3.8e-06 27.5 0.1 5.7e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AAZ35012.1 - 4.1e-05 23.6 0.0 8e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 AAZ35012.1 - 0.00023 21.0 1.0 0.0011 18.8 0.7 2.1 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 AAZ35012.1 - 0.00031 20.8 0.0 0.00061 19.9 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_25 PF13481.6 AAZ35012.1 - 0.0011 18.6 0.3 0.0033 17.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AAZ35012.1 - 0.0021 18.4 1.1 0.0053 17.2 1.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 AAZ35012.1 - 0.0026 18.2 0.2 0.0083 16.5 0.2 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 AAZ35012.1 - 0.0027 17.2 0.0 0.5 9.8 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA_15 PF13175.6 AAZ35012.1 - 0.0032 17.2 0.1 0.0044 16.8 0.1 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_27 PF13514.6 AAZ35012.1 - 0.0046 16.6 0.0 0.0082 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AAZ35012.1 - 0.0058 16.9 0.1 0.015 15.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 AAZ35012.1 - 0.012 15.9 0.6 0.053 13.8 0.6 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.9 AAZ35012.1 - 0.016 14.1 0.4 0.026 13.3 0.1 1.4 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_35 PF14516.6 AAZ35012.1 - 0.025 13.4 0.0 3.3 6.5 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain AAA_33 PF13671.6 AAZ35012.1 - 0.027 14.7 0.6 0.24 11.5 0.0 2.2 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 AAZ35012.1 - 0.033 14.1 0.1 0.049 13.5 0.1 1.5 1 1 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.17 AAZ35012.1 - 0.034 13.9 0.7 2.9 7.6 0.1 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein NB-ARC PF00931.22 AAZ35012.1 - 0.086 12.0 0.0 0.56 9.3 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain Zeta_toxin PF06414.12 AAZ35012.1 - 0.095 12.0 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_10 PF12846.7 AAZ35012.1 - 0.11 11.4 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_28 PF13521.6 AAZ35012.1 - 0.11 12.7 0.2 0.25 11.6 0.2 1.6 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 AAZ35012.1 - 0.15 11.9 0.1 1 9.1 0.1 1.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 AAZ35012.1 - 0.18 11.7 0.2 0.43 10.5 0.1 1.6 2 0 0 2 2 2 0 NTPase Cytidylate_kin PF02224.18 AAZ35012.1 - 0.19 11.4 0.1 0.32 10.7 0.1 1.4 1 0 0 1 1 1 0 Cytidylate kinase cobW PF02492.19 AAZ35012.1 - 0.2 11.2 0.1 0.32 10.5 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain FAD_binding_3 PF01494.19 AAZ35013.1 - 3.3e-18 66.0 0.1 6e-18 65.2 0.1 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 AAZ35013.1 - 4.4e-06 26.5 0.6 0.00052 19.7 0.1 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 AAZ35013.1 - 3.1e-05 23.4 0.2 7.4 5.7 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AAZ35013.1 - 0.00041 20.5 0.4 0.0013 18.9 0.1 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 AAZ35013.1 - 0.0029 18.1 0.1 0.018 15.6 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 AAZ35013.1 - 0.0034 16.7 0.1 0.45 9.7 0.0 2.5 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 AAZ35013.1 - 0.035 13.2 0.2 0.064 12.3 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 AAZ35013.1 - 0.073 12.1 0.2 0.1 11.6 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 AAZ35013.1 - 0.11 11.3 0.3 17 4.1 0.1 2.9 3 0 0 3 3 3 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 AAZ35013.1 - 0.16 11.3 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 AAZ35013.1 - 0.19 10.4 0.0 3.9 6.1 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.6 AAZ35013.1 - 0.21 10.8 0.0 3.3 6.9 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Phage_integrase PF00589.22 AAZ35014.1 - 4.6e-13 49.3 1.9 8.4e-13 48.5 1.3 1.7 2 0 0 2 2 2 1 Phage integrase family DUF244 PF03112.14 AAZ35014.1 - 0.03 14.2 0.0 0.067 13.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF AAA_assoc_C PF09821.9 AAZ35015.1 - 2.9e-41 140.7 0.1 4.5e-41 140.1 0.1 1.3 1 0 0 1 1 1 1 C-terminal AAA-associated domain ABC_tran PF00005.27 AAZ35015.1 - 8.6e-30 104.0 0.0 1.4e-29 103.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 AAZ35015.1 - 9.3e-06 25.3 0.0 2.4e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 AAZ35015.1 - 0.00013 21.9 0.1 0.088 12.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 AAZ35015.1 - 0.0078 16.1 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 AAZ35015.1 - 0.015 15.7 0.3 0.057 13.8 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.23 AAZ35015.1 - 0.024 14.7 0.1 0.046 13.8 0.1 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase NB-ARC PF00931.22 AAZ35015.1 - 0.026 13.7 0.0 0.044 13.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 AAZ35015.1 - 0.056 13.4 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 AAZ35015.1 - 0.069 13.4 0.0 0.39 11.0 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AAZ35015.1 - 0.084 13.4 0.0 0.12 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AAZ35015.1 - 0.089 12.5 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 AAZ35015.1 - 0.17 10.6 0.3 2.3 6.9 0.0 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class DUF87 PF01935.17 AAZ35015.1 - 0.21 11.6 0.1 0.48 10.5 0.1 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain FliG_C PF01706.16 AAZ35016.1 - 5.7e-45 151.9 9.2 4.5e-41 139.4 3.8 2.4 2 0 0 2 2 2 2 FliG C-terminal domain FliG_N PF14842.6 AAZ35016.1 - 2.5e-44 150.1 7.2 3.9e-34 117.3 0.3 3.4 2 1 0 3 3 3 3 FliG N-terminal domain FliG_M PF14841.6 AAZ35016.1 - 7.1e-28 96.7 7.1 1.1e-22 80.0 0.1 3.7 4 0 0 4 4 4 2 FliG middle domain MgtE_N PF03448.17 AAZ35016.1 - 9.8e-07 29.3 8.3 0.12 13.0 0.1 3.9 3 1 0 4 4 4 3 MgtE intracellular N domain DUF3150 PF11348.8 AAZ35016.1 - 0.0091 15.3 0.6 1.2 8.3 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF3150) ACCA PF03255.14 AAZ35016.1 - 0.056 13.3 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Beta-Casp PF10996.8 AAZ35017.1 - 2.4e-28 98.6 0.0 3.8e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 AAZ35017.1 - 1.4e-11 44.8 0.0 4.1e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 AAZ35017.1 - 5.2e-07 29.5 0.2 4.9e-06 26.4 0.0 2.3 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 AAZ35017.1 - 0.00054 19.5 0.0 0.0016 18.0 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Bac_luciferase PF00296.20 AAZ35018.1 - 2.6e-74 250.5 2.0 3.4e-74 250.1 2.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase SpoVR PF04293.13 AAZ35019.1 - 1.2e-176 587.5 2.9 1.5e-176 587.2 2.9 1.0 1 0 0 1 1 1 1 SpoVR like protein MCRS_N PF13325.6 AAZ35019.1 - 0.099 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein LysE PF01810.18 AAZ35020.1 - 1.5e-38 132.2 11.8 1.8e-38 132.0 11.8 1.0 1 0 0 1 1 1 1 LysE type translocator CAAD PF14159.6 AAZ35020.1 - 0.017 15.0 0.1 0.017 15.0 0.1 2.7 2 1 1 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase TerC PF03741.16 AAZ35020.1 - 0.02 14.6 10.3 0.084 12.5 0.3 2.2 2 0 0 2 2 2 0 Integral membrane protein TerC family COX7C PF02935.16 AAZ35020.1 - 0.072 13.4 0.3 0.25 11.6 0.3 2.0 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIc EF-hand_6 PF13405.6 AAZ35021.1 - 7.7e-23 78.4 4.3 0.00028 20.6 0.0 5.6 5 1 0 5 5 5 5 EF-hand domain EF-hand_1 PF00036.32 AAZ35021.1 - 3.4e-21 73.1 1.3 0.00014 21.2 0.0 5.2 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 AAZ35021.1 - 9.8e-19 67.6 4.5 7.1e-08 32.8 0.2 4.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 AAZ35021.1 - 2.4e-17 61.5 8.0 5.8e-05 22.4 0.1 4.8 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 AAZ35021.1 - 1.3e-13 50.5 0.3 0.0017 18.2 0.0 4.4 4 0 0 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 AAZ35021.1 - 3.6e-07 30.5 1.2 0.0033 17.7 0.0 4.1 2 2 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region Dimerisation PF08100.11 AAZ35021.1 - 0.024 14.7 0.9 17 5.5 0.0 3.7 4 0 0 4 4 4 0 Dimerisation domain EF-hand_9 PF14658.6 AAZ35021.1 - 0.12 12.7 0.1 4.1 7.8 0.0 3.1 4 0 0 4 4 4 0 EF-hand domain DUF1542 PF07564.11 AAZ35021.1 - 0.44 10.7 6.2 0.11 12.6 2.6 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) EF-hand_4 PF12763.7 AAZ35021.1 - 0.49 10.4 0.0 0.49 10.4 0.0 3.1 3 1 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand Excalibur PF05901.11 AAZ35021.1 - 0.71 10.5 3.8 46 4.7 0.0 3.8 4 0 0 4 4 4 0 Excalibur calcium-binding domain SpaA PF17802.1 AAZ35021.1 - 2.9 8.3 7.8 11 6.4 3.8 3.3 2 1 0 2 2 2 0 Prealbumin-like fold domain PALP PF00291.25 AAZ35022.1 - 1.7e-66 224.6 0.6 3.1e-66 223.8 0.6 1.4 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DFP PF04127.15 AAZ35022.1 - 0.051 13.4 0.1 0.081 12.8 0.1 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Exonuc_VII_L PF02601.15 AAZ35023.1 - 1.4e-97 326.9 1.6 1.8e-97 326.6 1.6 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit tRNA_anti_2 PF13742.6 AAZ35023.1 - 5.5e-29 100.2 0.0 1.5e-28 98.8 0.0 1.7 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA_anti-codon PF01336.25 AAZ35023.1 - 6.2e-11 42.1 0.0 1.4e-10 41.0 0.0 1.6 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain DUF4807 PF16065.5 AAZ35023.1 - 0.022 14.4 0.1 0.058 13.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4807) DUF2064 PF09837.9 AAZ35023.1 - 0.4 10.5 3.4 5.5 6.8 1.0 2.8 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2064) HATPase_c PF02518.26 AAZ35024.1 - 5.3e-22 78.5 0.0 9.8e-22 77.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAZ35024.1 - 3.1e-12 46.3 0.2 1e-11 44.7 0.1 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 AAZ35024.1 - 4.3e-06 26.7 0.2 1.2e-05 25.3 0.0 1.8 2 0 0 2 2 2 1 PAS fold HATPase_c_5 PF14501.6 AAZ35024.1 - 0.0013 18.6 0.0 0.0024 17.7 0.0 1.3 1 0 0 1 1 1 1 GHKL domain PAS_4 PF08448.10 AAZ35024.1 - 0.0013 19.0 0.0 0.0033 17.6 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 AAZ35024.1 - 0.0019 18.2 0.0 0.005 16.8 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 AAZ35024.1 - 0.0044 17.2 0.0 0.01 16.1 0.0 1.7 1 0 0 1 1 1 1 PAS domain HATPase_c_2 PF13581.6 AAZ35024.1 - 0.007 16.3 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 AAZ35024.1 - 0.0073 16.1 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_7 PF12860.7 AAZ35024.1 - 0.098 12.8 0.0 0.38 10.9 0.0 2.0 2 0 0 2 2 2 0 PAS fold Ureidogly_lyase PF04115.12 AAZ35025.1 - 1.4e-52 178.2 0.0 1.7e-52 178.0 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate lyase ClpS PF02617.17 AAZ35026.1 - 6e-34 115.7 0.1 7.8e-34 115.3 0.1 1.2 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS Peptidase_M20 PF01546.28 AAZ35027.1 - 2.7e-30 105.7 0.0 3.6e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AAZ35027.1 - 1e-24 86.5 0.0 1.6e-24 85.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 AAZ35027.1 - 0.0027 17.4 0.0 0.0039 16.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 TonB_dep_Rec PF00593.24 AAZ35028.1 - 2.5e-44 153.0 22.1 2.5e-44 153.0 22.1 1.5 2 0 0 2 2 2 1 TonB dependent receptor Plug PF07715.15 AAZ35028.1 - 4.8e-11 43.2 0.7 1.1e-10 42.0 0.7 1.7 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 AAZ35028.1 - 1.5e-05 24.2 0.0 5e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 Outer membrane protein beta-barrel family DUF560 PF04575.13 AAZ35028.1 - 0.0089 15.5 0.6 0.021 14.3 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF560) GntR PF00392.21 AAZ35029.1 - 7.3e-09 35.1 0.1 2.4e-08 33.5 0.1 1.9 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_11 PF08279.12 AAZ35029.1 - 5e-05 23.2 0.1 0.00015 21.7 0.1 1.8 1 0 0 1 1 1 1 HTH domain HTH_Crp_2 PF13545.6 AAZ35029.1 - 0.0024 17.8 1.7 0.0075 16.2 0.1 2.5 2 1 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_36 PF13730.6 AAZ35029.1 - 0.0058 16.6 0.0 0.016 15.1 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 AAZ35029.1 - 0.0082 15.7 0.3 0.034 13.7 0.1 2.2 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_41 PF14502.6 AAZ35029.1 - 0.018 14.7 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Fe_dep_repress PF01325.19 AAZ35029.1 - 0.039 14.1 0.2 0.078 13.2 0.2 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain RPA_C PF08784.11 AAZ35029.1 - 0.11 13.1 0.0 0.21 12.2 0.0 1.4 1 0 0 1 1 1 0 Replication protein A C terminal Glyco_hydro_cc PF11790.8 AAZ35030.1 - 1.7e-60 204.5 1.0 2.1e-60 204.3 1.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_trans_4_4 PF13579.6 AAZ35030.1 - 0.12 12.9 0.1 0.2 12.1 0.1 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain RcnB PF11776.8 AAZ35031.1 - 4.8e-15 55.3 0.0 6.1e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 Nickel/cobalt transporter regulator PhrC_PhrF PF11131.8 AAZ35031.1 - 0.00063 19.3 0.4 0.0021 17.6 0.2 1.8 2 0 0 2 2 2 1 Rap-phr extracellular signalling HrpA_pilin PF09589.10 AAZ35032.1 - 1.8e-05 25.3 4.2 2.1e-05 25.1 4.2 1.3 1 1 0 1 1 1 1 HrpA pilus formation protein MFS_1 PF07690.16 AAZ35033.1 - 1e-32 113.5 60.4 9.6e-29 100.4 49.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 AAZ35033.1 - 3.9e-05 22.4 28.8 0.0015 17.2 5.7 2.4 2 1 0 2 2 2 2 MFS/sugar transport protein Pam17 PF08566.10 AAZ35033.1 - 8 6.3 5.9 1.5 8.6 1.2 2.0 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 Band_7 PF01145.25 AAZ35034.1 - 8.1e-26 91.1 5.9 8.1e-26 91.1 5.9 1.9 2 0 0 2 2 2 1 SPFH domain / Band 7 family HflK_N PF12221.8 AAZ35034.1 - 2.6e-17 62.5 9.7 8e-17 61.0 9.7 1.9 1 0 0 1 1 1 1 Bacterial membrane protein N terminal Gp-FAR-1 PF05823.12 AAZ35034.1 - 0.022 15.1 0.1 0.065 13.6 0.0 1.7 1 1 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Band_7_1 PF13421.6 AAZ35034.1 - 0.053 13.2 0.4 0.11 12.2 0.1 1.6 2 0 0 2 2 2 0 SPFH domain-Band 7 family PSII_Pbs27 PF13326.6 AAZ35034.1 - 0.071 13.4 1.3 8.3 6.7 0.5 2.3 1 1 1 2 2 2 0 Photosystem II Pbs27 DivIVA PF05103.13 AAZ35034.1 - 5.6 7.1 8.4 0.098 12.7 1.1 2.0 2 1 0 2 2 2 0 DivIVA protein Serglycin PF04360.12 AAZ35034.1 - 7 6.6 7.7 19 5.2 0.2 2.4 2 0 0 2 2 2 0 Serglycin CAP PF00188.26 AAZ35035.1 - 5e-18 66.2 1.1 8.2e-18 65.5 0.6 1.7 2 0 0 2 2 2 1 Cysteine-rich secretory protein family pRN1_helical PF13010.6 AAZ35035.1 - 0.044 13.8 0.0 0.071 13.1 0.0 1.3 1 0 0 1 1 1 0 Primase helical domain MdoG PF04349.12 AAZ35036.1 - 3.3e-187 623.2 0.0 3.7e-187 623.0 0.0 1.0 1 0 0 1 1 1 1 Periplasmic glucan biosynthesis protein, MdoG Ala_racemase_N PF01168.20 AAZ35037.1 - 2.4e-34 118.9 0.1 3.2e-34 118.5 0.1 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.6 AAZ35037.1 - 7e-22 77.9 0.1 1.4e-21 76.9 0.1 1.6 1 0 0 1 1 1 1 Putative serine dehydratase domain Haem_degrading PF03928.14 AAZ35038.1 - 1.4e-32 112.2 1.3 1.6e-32 112.0 1.3 1.0 1 0 0 1 1 1 1 Haem-degrading Diacid_rec PF05651.13 AAZ35038.1 - 0.055 13.2 0.4 0.11 12.2 0.4 1.4 1 0 0 1 1 1 0 Putative sugar diacid recognition GAF_2 PF13185.6 AAZ35038.1 - 0.085 13.1 1.8 0.83 9.9 1.8 2.1 1 1 0 1 1 1 0 GAF domain TamB PF04357.13 AAZ35039.1 - 2.1e-59 201.7 16.2 6.8e-54 183.6 2.3 5.3 4 2 1 5 5 5 4 TamB, inner membrane protein subunit of TAM complex AIRC PF00731.20 AAZ35041.1 - 7.6e-63 210.5 0.7 9.5e-63 210.2 0.7 1.1 1 0 0 1 1 1 1 AIR carboxylase DUF2802 PF10975.8 AAZ35042.1 - 1.7e-22 79.3 1.3 1.1e-21 76.8 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2802) Unstab_antitox PF09720.10 AAZ35042.1 - 0.0047 16.9 0.5 0.011 15.8 0.5 1.6 1 0 0 1 1 1 1 Putative addiction module component DnaB_bind PF10410.9 AAZ35042.1 - 0.25 11.6 2.5 12 6.2 0.5 2.7 3 0 0 3 3 3 0 DnaB-helicase binding domain of primase DUF4407 PF14362.6 AAZ35042.1 - 0.85 8.9 6.1 0.08 12.3 1.2 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) adh_short_C2 PF13561.6 AAZ35043.1 - 1.2e-30 106.9 0.0 2.7e-17 63.1 0.0 2.4 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAZ35043.1 - 2.2e-21 76.2 0.0 9.1e-16 57.9 0.0 2.4 2 1 0 2 2 2 2 short chain dehydrogenase Epimerase PF01370.21 AAZ35043.1 - 1.5e-05 24.6 0.0 2.1e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 AAZ35043.1 - 0.0044 16.2 0.0 0.011 14.9 0.0 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain 2-Hacid_dh_C PF02826.19 AAZ35043.1 - 0.029 13.7 0.0 0.066 12.6 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF4096 PF13340.6 AAZ35045.1 - 5.8e-25 87.3 0.4 1.5e-24 86.0 0.4 1.8 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1 PF01609.21 AAZ35045.1 - 3.2e-14 53.1 0.0 5.7e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AAZ35045.1 - 7.2e-10 39.1 0.2 2.1e-09 37.6 0.2 1.9 1 0 0 1 1 1 1 Transposase DDE domain HTH_Tnp_Tc3_2 PF01498.18 AAZ35045.1 - 0.061 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Transposase Peptidase_S41 PF03572.18 AAZ35046.1 - 2.6e-58 196.3 0.4 4.1e-58 195.6 0.4 1.3 1 0 0 1 1 1 1 Peptidase family S41 PDZ_6 PF17820.1 AAZ35046.1 - 1.4e-14 53.7 0.1 3.7e-14 52.3 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 AAZ35046.1 - 1.9e-12 47.3 0.6 5.1e-12 45.9 0.6 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 AAZ35046.1 - 1.7e-09 37.9 0.9 4.3e-09 36.6 0.9 1.7 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 AAZ35046.1 - 0.0056 16.6 0.2 0.014 15.4 0.2 1.8 1 0 0 1 1 1 1 Tricorn protease PDZ domain TSP_NTD PF17804.1 AAZ35046.1 - 0.14 12.4 0.0 0.23 11.7 0.0 1.2 1 0 0 1 1 1 0 Tail specific protease N-terminal domain SMC_ScpA PF02616.14 AAZ35047.1 - 1.6e-29 103.5 1.5 8.7e-20 71.7 0.2 2.2 2 1 0 2 2 2 2 Segregation and condensation protein ScpA Rad21_Rec8 PF04824.16 AAZ35047.1 - 0.027 13.8 0.0 0.047 13.0 0.0 1.4 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein T2SSG PF08334.11 AAZ35048.1 - 1.5e-38 131.2 0.1 1.8e-38 130.9 0.1 1.1 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein G N_methyl PF07963.12 AAZ35048.1 - 6.7e-10 38.1 1.7 9.7e-10 37.6 1.7 1.3 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif ComP_DUS PF16732.5 AAZ35048.1 - 0.14 13.0 0.2 0.21 12.5 0.2 1.2 1 0 0 1 1 1 0 Type IV minor pilin ComP, DNA uptake sequence receptor GCV_T PF01571.21 AAZ35049.1 - 0.00048 19.6 0.0 0.0013 18.1 0.0 1.6 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain HTH_IclR PF09339.10 AAZ35050.1 - 1.1e-13 50.7 0.0 2e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain IclR PF01614.18 AAZ35050.1 - 2.6e-08 33.7 0.0 4.2e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial transcriptional regulator TrmB PF01978.19 AAZ35050.1 - 0.0014 18.5 0.0 0.0026 17.6 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 AAZ35050.1 - 0.0059 16.5 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 AAZ35050.1 - 0.0089 15.6 0.0 0.082 12.5 0.0 2.3 1 1 1 2 2 2 1 Winged helix-turn-helix DNA-binding Vps23_core PF09454.10 AAZ35050.1 - 0.055 13.4 0.0 0.22 11.5 0.0 2.1 2 0 0 2 2 2 0 Vps23 core domain HTH_20 PF12840.7 AAZ35050.1 - 0.13 12.3 0.0 0.56 10.3 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain TFIIE_beta PF02186.15 AAZ35050.1 - 0.19 12.0 0.0 0.5 10.7 0.0 1.6 1 0 0 1 1 1 0 TFIIE beta subunit core domain PilZ PF07238.14 AAZ35051.1 - 2.8e-14 53.3 0.1 1.2e-13 51.3 0.0 2.0 2 0 0 2 2 2 1 PilZ domain HlyD_3 PF13437.6 AAZ35051.1 - 8.5e-10 39.3 0.1 4e-08 33.9 0.0 3.1 3 0 0 3 3 3 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AAZ35051.1 - 5.8e-05 22.8 0.0 0.0045 16.8 0.0 3.4 3 0 0 3 3 3 1 Biotin-lipoyl like HlyD_D23 PF16576.5 AAZ35051.1 - 0.00031 20.0 0.1 0.012 14.8 0.0 2.8 2 1 1 3 3 3 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl PF00364.22 AAZ35051.1 - 0.0052 16.6 0.0 0.93 9.4 0.0 3.4 4 0 0 4 4 4 1 Biotin-requiring enzyme MCPsignal PF00015.21 AAZ35052.1 - 8.6e-35 120.1 18.9 8.6e-35 120.1 18.9 2.2 2 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain PAS_3 PF08447.12 AAZ35052.1 - 5.7e-23 81.0 0.0 6e-14 52.1 0.0 3.6 3 1 1 4 4 4 2 PAS fold PAS_4 PF08448.10 AAZ35052.1 - 3.4e-20 72.4 0.2 1.7e-10 41.1 0.0 2.7 3 0 0 3 3 3 2 PAS fold PAS_9 PF13426.7 AAZ35052.1 - 1.8e-18 66.7 0.0 5.4e-08 33.0 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 AAZ35052.1 - 2.1e-15 56.7 0.7 7e-07 29.2 0.0 2.9 4 0 0 4 4 4 2 PAS fold PAS_11 PF14598.6 AAZ35052.1 - 0.051 13.7 0.0 0.33 11.1 0.0 2.1 2 0 0 2 2 2 0 PAS domain T7SS_ESX_EspC PF10824.8 AAZ35052.1 - 0.64 10.5 8.6 0.11 13.0 2.9 2.6 2 2 2 4 4 4 0 Excreted virulence factor EspC, type VII ESX diderm Glyco_transf_9 PF01075.17 AAZ35053.1 - 3.1e-75 252.7 0.0 3.9e-75 252.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 9 (heptosyltransferase) Kinase-PPPase PF03618.14 AAZ35054.1 - 1.3e-77 261.0 0.0 1.5e-77 260.8 0.0 1.0 1 0 0 1 1 1 1 Kinase/pyrophosphorylase MFS_1 PF07690.16 AAZ35055.1 - 1.4e-46 159.1 63.8 1.7e-45 155.5 37.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 AAZ35055.1 - 0.0033 16.8 17.4 0.11 11.7 8.4 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB ATG22 PF11700.8 AAZ35055.1 - 0.015 13.9 0.2 0.015 13.9 0.2 2.6 3 0 0 3 3 3 0 Vacuole effluxer Atg22 like DUF2157 PF09925.9 AAZ35055.1 - 5.7 6.7 16.4 1 9.1 6.0 3.3 2 2 1 3 3 3 0 Predicted membrane protein (DUF2157) YcgR PF07317.12 AAZ35056.1 - 1e-23 83.2 0.0 2e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 Flagellar regulator YcgR PilZ PF07238.14 AAZ35056.1 - 6e-10 39.4 0.1 1e-09 38.6 0.1 1.4 1 0 0 1 1 1 1 PilZ domain DctM PF06808.12 AAZ35057.1 - 1.1e-96 324.3 49.4 1.2e-96 324.1 49.4 1.0 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporter, DctM component GerE PF00196.19 AAZ35058.1 - 5.6e-19 67.4 0.1 6.6e-19 67.2 0.1 1.1 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AAZ35058.1 - 0.002 17.8 0.0 0.0031 17.2 0.0 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 AAZ35058.1 - 0.031 14.1 0.2 0.058 13.2 0.2 1.6 1 1 0 1 1 1 0 Homeodomain-like domain HAD_2 PF13419.6 AAZ35059.1 - 1.2e-23 84.1 0.0 6e-23 81.8 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAZ35059.1 - 1.8e-14 54.5 1.1 1.6e-13 51.4 1.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AAZ35059.1 - 2.1e-09 37.3 0.1 3.6e-09 36.6 0.1 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 AAZ35059.1 - 0.0013 19.2 1.8 0.0025 18.2 1.8 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 AAZ35059.1 - 0.032 14.1 0.2 0.075 12.9 0.2 1.6 2 0 0 2 2 2 0 Acid Phosphatase Glyco_hydro_19 PF00182.19 AAZ35060.1 - 6.9e-10 39.2 0.0 1e-09 38.7 0.0 1.4 1 0 0 1 1 1 1 Chitinase class I Lon_C PF05362.13 AAZ35061.1 - 9.1e-77 257.2 0.0 1.5e-76 256.5 0.0 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 AAZ35061.1 - 3.4e-24 85.9 0.0 6.7e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 AAZ35061.1 - 2.9e-23 82.7 0.0 5.4e-23 81.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 AAZ35061.1 - 4.2e-09 36.3 0.0 7.8e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 AAZ35061.1 - 1.9e-08 34.4 0.0 4e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AAZ35061.1 - 2.5e-05 24.7 0.1 0.00019 21.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_PrkA PF08298.11 AAZ35061.1 - 0.0001 21.3 0.1 0.00028 19.9 0.0 1.6 2 0 0 2 2 2 1 PrkA AAA domain RuvB_N PF05496.12 AAZ35061.1 - 0.00031 20.5 0.1 0.0025 17.6 0.1 2.3 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 AAZ35061.1 - 0.00048 20.4 0.3 0.028 14.7 0.2 3.1 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.11 AAZ35061.1 - 0.00069 19.5 0.0 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 AAZ35061.1 - 0.0022 18.6 0.0 0.0056 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain SKI PF01202.22 AAZ35061.1 - 0.0033 17.5 0.2 0.038 14.1 0.0 2.2 2 0 0 2 2 2 1 Shikimate kinase AAA_2 PF07724.14 AAZ35061.1 - 0.0036 17.4 0.0 0.0082 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 AAZ35061.1 - 0.0083 15.4 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 AAZ35061.1 - 0.0091 16.2 0.0 0.019 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 AAZ35061.1 - 0.093 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_17 PF13207.6 AAZ35061.1 - 0.13 12.7 1.2 0.42 11.0 0.0 2.4 3 0 0 3 3 3 0 AAA domain CCDC-167 PF15188.6 AAZ35061.1 - 0.19 12.1 1.0 0.75 10.2 0.0 2.3 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 BPD_transp_1 PF00528.22 AAZ35062.1 - 2.6e-25 89.2 10.5 2.6e-25 89.2 10.5 1.6 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 AAZ35062.1 - 0.00012 22.0 0.0 0.00012 22.0 0.0 3.8 5 0 0 5 5 5 1 N-terminal TM domain of oligopeptide transport permease C DUF1072 PF06380.11 AAZ35062.1 - 4 7.4 6.9 0.42 10.5 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) PilZ PF07238.14 AAZ35063.1 - 1.2e-11 44.8 0.0 1.5e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 PilZ domain DUF3459 PF11941.8 AAZ35063.1 - 0.11 12.8 0.0 0.16 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) SBP_bac_5 PF00496.22 AAZ35064.1 - 2.4e-71 240.7 0.6 3.2e-71 240.3 0.6 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle T6SS_HCP PF05638.12 AAZ35065.1 - 1.5e-34 119.2 0.0 1.7e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 Type VI secretion system effector, Hcp rve PF00665.26 AAZ35066.1 - 3.7e-34 117.5 0.1 5.8e-34 116.8 0.1 1.3 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 AAZ35066.1 - 5.5e-12 46.1 0.0 7.7e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 DDE domain rve_3 PF13683.6 AAZ35066.1 - 7.3e-11 41.7 0.8 7.3e-11 41.7 0.8 1.8 2 0 0 2 2 2 1 Integrase core domain HTH_21 PF13276.6 AAZ35066.1 - 5.2e-10 39.3 1.4 1.3e-09 38.0 0.1 2.2 2 0 0 2 2 2 1 HTH-like domain rve_2 PF13333.6 AAZ35066.1 - 0.0017 18.5 0.0 0.0033 17.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain HAD_2 PF13419.6 AAZ35068.1 - 6.2e-32 111.1 0.0 7.2e-32 110.9 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAZ35068.1 - 2.2e-18 67.4 0.1 2.7e-17 63.8 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AAZ35068.1 - 1e-11 44.7 0.1 2.1e-11 43.7 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 AAZ35068.1 - 2.3e-09 37.9 0.0 3.3e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AAZ35068.1 - 0.0063 16.3 0.5 6.7 6.4 0.2 3.0 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AAZ35068.1 - 0.067 13.3 0.0 0.59 10.3 0.0 2.1 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase bMG1 PF17970.1 AAZ35069.1 - 3.1e-51 171.8 0.1 8.8e-51 170.4 0.1 1.8 1 0 0 1 1 1 1 Bacterial Alpha-2-macroglobulin MG1 domain bMG5 PF17972.1 AAZ35069.1 - 1.4e-43 148.3 1.0 3.3e-42 143.9 0.0 3.7 4 0 0 4 4 4 1 Bacterial Alpha-2-macroglobulin MG5 domain bMG6 PF17962.1 AAZ35069.1 - 4.2e-34 117.1 0.3 9.3e-33 112.7 0.3 2.7 2 0 0 2 2 2 1 Bacterial macroglobulin domain 6 bMG10 PF17973.1 AAZ35069.1 - 2.2e-27 95.8 0.0 1.3e-26 93.3 0.0 2.4 2 0 0 2 2 2 1 Bacterial Alpha-2-macroglobulin MG10 domain bMG3 PF11974.8 AAZ35069.1 - 3e-23 81.8 0.2 1.3e-22 79.7 0.2 2.3 1 0 0 1 1 1 1 Bacterial alpha-2-macroglobulin MG3 domain MG2 PF01835.19 AAZ35069.1 - 9e-23 80.6 0.1 7.4e-21 74.4 0.0 4.1 5 0 0 5 5 4 1 MG2 domain A2M_BRD PF07703.14 AAZ35069.1 - 7.6e-14 52.3 0.0 3.9e-13 50.0 0.0 2.3 1 0 0 1 1 1 1 Alpha-2-macroglobulin bait region domain TED_complement PF07678.14 AAZ35069.1 - 3.6e-11 42.6 0.0 6.1e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M PF00207.22 AAZ35069.1 - 6.7e-11 41.9 0.0 1.6e-09 37.5 0.0 2.5 2 0 0 2 2 2 1 Alpha-2-macroglobulin family CarboxypepD_reg PF13620.6 AAZ35069.1 - 0.017 15.3 0.1 0.41 11.0 0.0 3.4 3 0 0 3 3 3 0 Carboxypeptidase regulatory-like domain Big_6 PF17936.1 AAZ35069.1 - 0.02 15.1 3.4 6.6 7.1 0.1 4.6 4 0 0 4 4 4 0 Bacterial Ig domain DUF11 PF01345.18 AAZ35069.1 - 0.86 9.9 2.8 84 3.6 0.0 4.6 5 0 0 5 5 5 0 Domain of unknown function DUF11 GreA_GreB PF01272.19 AAZ35070.1 - 1.7e-22 79.1 0.0 2.8e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Transcription elongation factor, GreA/GreB, C-term GreA_GreB_N PF03449.15 AAZ35070.1 - 0.03 14.5 0.8 2 8.6 0.2 2.3 1 1 1 2 2 2 0 Transcription elongation factor, N-terminal SBD_N PF07005.11 AAZ35071.1 - 6e-71 238.8 0.7 4.8e-70 235.9 0.1 2.2 2 1 0 2 2 2 1 Sugar-binding N-terminal domain NBD_C PF17042.5 AAZ35071.1 - 2.7e-41 141.9 4.3 7.7e-41 140.4 4.3 1.8 1 0 0 1 1 1 1 Nucleotide-binding C-terminal domain EccE PF11203.8 AAZ35071.1 - 1.6 9.1 6.2 0.51 10.7 0.4 2.9 3 0 0 3 3 3 0 Putative type VII ESX secretion system translocon, EccE PALP PF00291.25 AAZ35072.1 - 2.4e-42 145.4 0.0 2.9e-42 145.1 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Sin_N PF04801.13 AAZ35072.1 - 0.13 11.5 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region FabA PF07977.13 AAZ35073.1 - 2.5e-40 137.3 0.0 2.9e-40 137.1 0.0 1.0 1 0 0 1 1 1 1 FabA-like domain 4HBT PF03061.22 AAZ35073.1 - 0.00031 21.0 0.0 0.00043 20.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily MaoC_dehydratas PF01575.19 AAZ35073.1 - 0.00072 19.1 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain 4HBT_2 PF13279.6 AAZ35073.1 - 0.067 13.7 0.0 0.075 13.5 0.0 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily ATP-grasp_4 PF13535.6 AAZ35074.1 - 6.6e-19 68.1 0.0 1.9e-18 66.6 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.14 AAZ35074.1 - 4.2e-13 49.6 0.0 7.1e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 AAZ35074.1 - 1e-07 31.7 0.0 6.6e-06 25.8 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain LAL_C2 PF18603.1 AAZ35074.1 - 3.3e-05 24.0 0.0 9.4e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 L-amino acid ligase C-terminal domain 2 ATPgrasp_Ter PF15632.6 AAZ35074.1 - 0.003 17.3 0.0 0.0068 16.2 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.17 AAZ35074.1 - 0.0067 15.9 0.0 0.022 14.2 0.0 1.8 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain GARS_A PF01071.19 AAZ35074.1 - 0.0072 16.1 0.0 0.024 14.4 0.0 1.8 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Ppx-GppA PF02541.16 AAZ35075.1 - 1e-74 251.5 0.0 1.5e-74 251.0 0.0 1.1 1 0 0 1 1 1 1 Ppx/GppA phosphatase family ADP_ribosyl_GH PF03747.14 AAZ35076.1 - 9.3e-47 160.1 1.7 1.4e-46 159.5 1.7 1.3 1 1 0 1 1 1 1 ADP-ribosylglycohydrolase 2-ph_phosp PF04029.14 AAZ35076.1 - 0.16 11.1 0.1 0.45 9.7 0.0 1.7 2 0 0 2 2 2 0 2-phosphosulpholactate phosphatase Biotin_lipoyl_2 PF13533.6 AAZ35077.1 - 1.3e-16 60.1 0.7 6.1e-16 58.0 0.1 2.4 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 AAZ35077.1 - 2.8e-12 47.3 2.8 5.7e-07 30.2 0.2 3.2 3 0 0 3 3 3 2 HlyD family secretion protein HlyD_D23 PF16576.5 AAZ35077.1 - 7e-11 41.7 0.8 1.1e-10 41.1 0.8 1.3 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl PF00364.22 AAZ35077.1 - 0.002 17.9 0.0 0.0066 16.3 0.0 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme QRPTase_N PF02749.16 AAZ35077.1 - 0.069 13.2 0.0 1.9 8.6 0.0 2.8 3 0 0 3 3 3 0 Quinolinate phosphoribosyl transferase, N-terminal domain DUF4131 PF13567.6 AAZ35077.1 - 0.069 12.8 0.8 0.14 11.8 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) PTS_EIIA_1 PF00358.20 AAZ35077.1 - 0.075 12.8 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Peptidase_M23 PF01551.22 AAZ35077.1 - 0.11 12.7 0.0 2.2 8.6 0.0 2.4 2 0 0 2 2 2 0 Peptidase family M23 LysR_substrate PF03466.20 AAZ35078.1 - 7.5e-31 107.1 5.1 9.3e-31 106.8 5.1 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ35078.1 - 1.6e-15 56.8 0.0 3.4e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AAZ35078.1 - 0.0014 18.4 0.1 0.0041 16.9 0.1 1.8 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_20 PF12840.7 AAZ35078.1 - 0.0045 17.0 0.4 0.02 15.0 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.7 AAZ35078.1 - 0.056 13.3 0.1 0.38 10.7 0.0 2.2 2 0 0 2 2 2 0 MarR family HTH_24 PF13412.6 AAZ35078.1 - 0.16 11.6 0.1 0.35 10.5 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding FlgI PF02119.16 AAZ35079.1 - 6.3e-142 472.6 5.5 7.2e-142 472.4 5.5 1.0 1 0 0 1 1 1 1 Flagellar P-ring protein SepF PF04472.12 AAZ35079.1 - 0.0026 18.0 0.0 0.0084 16.4 0.0 1.9 1 0 0 1 1 1 1 Cell division protein SepF Flagellin_IN PF07196.13 AAZ35079.1 - 0.011 15.9 2.9 4.4 7.6 0.0 3.6 5 0 0 5 5 5 0 Flagellin hook IN motif 2OG-Fe_Oxy_2 PF10014.9 AAZ35080.1 - 1.1e-32 113.5 0.0 1.3e-32 113.2 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe dioxygenase Ribosomal_S18 PF01084.20 AAZ35081.1 - 5.3e-25 87.4 0.2 6.9e-25 87.0 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S18 HhH-GPD PF00730.25 AAZ35081.1 - 0.07 13.6 0.1 0.072 13.6 0.1 1.1 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein SpoU_methylase PF00588.19 AAZ35082.1 - 4.7e-39 133.8 0.0 6.3e-39 133.4 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 AAZ35082.1 - 1.1e-19 70.5 0.0 3.1e-19 69.0 0.1 1.7 2 0 0 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding Na_H_Exchanger PF00999.21 AAZ35083.1 - 7.8e-68 229.0 48.4 9.5e-68 228.7 48.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TrkA_N PF02254.18 AAZ35083.1 - 3.9e-25 88.4 0.7 7.8e-25 87.4 0.0 1.8 2 0 0 2 2 2 1 TrkA-N domain 2-Hacid_dh_C PF02826.19 AAZ35083.1 - 0.0019 17.6 0.1 0.0077 15.6 0.0 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CTP_transf_like PF01467.26 AAZ35083.1 - 0.18 12.0 0.0 0.35 11.1 0.0 1.4 1 0 0 1 1 1 0 Cytidylyltransferase-like adh_short_C2 PF13561.6 AAZ35084.1 - 9.3e-20 71.2 0.1 5.1e-11 42.6 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAZ35084.1 - 2.4e-08 33.7 0.8 6.2e-08 32.3 0.6 1.7 1 1 1 2 2 2 1 short chain dehydrogenase THF_DHG_CYH_C PF02882.19 AAZ35084.1 - 0.064 12.6 0.1 0.22 10.8 0.1 1.8 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 AAZ35084.1 - 0.15 12.0 0.1 0.16 11.9 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CheZ PF04344.13 AAZ35085.1 - 6e-74 248.4 1.0 7.5e-74 248.0 1.0 1.1 1 0 0 1 1 1 1 Chemotaxis phosphatase, CheZ phage_tail_N PF08400.10 AAZ35085.1 - 0.0028 17.7 0.0 0.005 16.8 0.0 1.4 1 0 0 1 1 1 1 Prophage tail fibre N-terminal ArnB_C PF18677.1 AAZ35085.1 - 0.046 13.8 1.2 6.3 7.0 0.1 2.8 1 1 1 2 2 2 0 Archaellum regulatory network B, C-terminal domain HSCB_C PF07743.13 AAZ35085.1 - 0.062 13.8 0.1 3.1 8.4 0.0 3.1 2 2 0 2 2 2 0 HSCB C-terminal oligomerisation domain Mer2 PF09074.10 AAZ35085.1 - 0.081 12.7 0.9 2.9 7.6 0.1 2.3 1 1 0 2 2 2 0 Mer2 Noelin-1 PF12308.8 AAZ35085.1 - 0.19 11.7 0.4 1 9.4 0.0 2.3 1 1 1 2 2 2 0 Neurogenesis glycoprotein ILVD_EDD PF00920.21 AAZ35086.1 - 2.6e-163 544.4 0.2 3e-163 544.2 0.2 1.0 1 0 0 1 1 1 1 Dehydratase family TPR_19 PF14559.6 AAZ35087.1 - 5.5e-11 42.8 37.5 8.8e-07 29.4 1.8 6.0 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 AAZ35087.1 - 1.4e-10 41.1 34.1 1.3e-05 25.6 1.9 7.2 3 2 5 8 8 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 AAZ35087.1 - 6.8e-10 38.4 0.1 0.00015 21.7 0.0 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 AAZ35087.1 - 2.5e-09 36.5 16.8 0.00079 19.4 0.2 6.6 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 AAZ35087.1 - 1.8e-08 34.0 2.5 0.00082 19.0 0.2 3.3 2 0 0 2 2 2 2 TPR repeat HEAT_2 PF13646.6 AAZ35087.1 - 2.8e-07 30.8 4.7 2.8e-07 30.8 4.7 2.9 3 1 0 3 3 3 1 HEAT repeats TPR_6 PF13174.6 AAZ35087.1 - 3e-06 27.5 12.0 0.023 15.3 0.2 5.4 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 AAZ35087.1 - 1e-05 25.5 12.2 0.13 12.7 0.2 6.2 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_20 PF14561.6 AAZ35087.1 - 1.1e-05 25.7 24.0 0.00024 21.4 1.0 4.6 2 2 2 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 AAZ35087.1 - 1.7e-05 25.3 36.1 3.5e-05 24.4 2.0 6.3 4 2 3 7 7 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 AAZ35087.1 - 9.3e-05 22.1 4.4 0.0055 16.5 0.0 4.9 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 AAZ35087.1 - 0.00014 21.9 18.4 0.012 15.8 1.4 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 AAZ35087.1 - 0.00024 21.3 1.5 0.00024 21.3 1.5 4.6 4 1 1 5 5 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 AAZ35087.1 - 0.0011 19.0 0.8 0.027 14.6 0.2 2.9 3 0 0 3 3 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 AAZ35087.1 - 0.0024 17.8 1.6 0.11 12.6 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat HEAT PF02985.22 AAZ35087.1 - 0.0024 18.0 0.3 1.5 9.3 0.2 3.2 2 0 0 2 2 2 1 HEAT repeat DUF4042 PF13251.6 AAZ35087.1 - 0.044 13.5 0.4 0.12 12.0 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4042) ANAPC3 PF12895.7 AAZ35087.1 - 0.061 13.5 10.8 0.22 11.7 0.6 3.5 2 1 3 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 SRP_TPR_like PF17004.5 AAZ35087.1 - 0.069 13.2 0.2 21 5.1 0.0 2.7 3 0 0 3 3 3 0 Putative TPR-like repeat ANAPC5 PF12862.7 AAZ35087.1 - 0.091 12.8 4.5 2.7 8.1 0.6 2.6 1 1 0 2 2 2 0 Anaphase-promoting complex subunit 5 RPN7 PF10602.9 AAZ35087.1 - 0.097 12.4 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 26S proteasome subunit RPN7 TPR_21 PF09976.9 AAZ35087.1 - 0.21 11.3 18.9 0.39 10.4 6.0 3.9 2 1 1 3 3 3 0 Tetratricopeptide repeat-like domain SNARE PF05739.19 AAZ35087.1 - 0.23 11.5 1.2 2.2 8.4 0.1 2.4 2 0 0 2 2 2 0 SNARE domain TPR_15 PF13429.6 AAZ35087.1 - 0.46 9.7 22.9 0.027 13.7 8.3 3.6 2 1 2 4 4 4 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 AAZ35087.1 - 4.2 7.8 11.5 4.8 7.6 0.4 3.3 3 1 1 4 4 4 0 Alkyl sulfatase dimerisation HEAT_EZ PF13513.6 AAZ35087.1 - 8.5 7.0 13.2 1.4 9.5 0.2 3.6 4 0 0 4 4 2 0 HEAT-like repeat tRNA_m1G_MT PF01746.21 AAZ35088.1 - 1e-63 214.6 0.0 1.2e-63 214.4 0.0 1.0 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase PilZ PF07238.14 AAZ35090.1 - 1.2e-12 48.1 0.1 1.4e-12 47.8 0.1 1.1 1 0 0 1 1 1 1 PilZ domain RlmM_FDX PF18125.1 AAZ35091.1 - 1.6e-18 67.0 0.0 2.7e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 RlmM ferredoxin-like domain FtsJ PF01728.19 AAZ35091.1 - 3.7e-07 30.4 0.0 5.7e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase ABC_tran PF00005.27 AAZ35092.1 - 2.1e-32 112.5 0.0 3.8e-32 111.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter TOBE_2 PF08402.10 AAZ35092.1 - 1.4e-12 47.6 0.3 7.6e-12 45.2 0.1 2.2 2 0 0 2 2 2 1 TOBE domain AAA_21 PF13304.6 AAZ35092.1 - 1.2e-05 25.3 0.1 0.013 15.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 AAZ35092.1 - 0.00045 20.7 0.0 0.002 18.5 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AAZ35092.1 - 0.0015 18.8 1.8 0.029 14.6 1.8 2.1 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 AAZ35092.1 - 0.0036 16.8 0.1 0.16 11.4 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AAZ35092.1 - 0.0051 17.2 0.1 0.0088 16.4 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 AAZ35092.1 - 0.0061 16.5 0.0 0.01 15.8 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 AAZ35092.1 - 0.01 15.6 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 AAZ35092.1 - 0.024 14.2 0.4 0.4 10.2 0.0 2.4 2 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 AAZ35092.1 - 0.033 13.2 0.1 0.06 12.4 0.0 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein ABC_ATPase PF09818.9 AAZ35092.1 - 0.19 10.5 0.7 0.53 9.0 0.1 2.0 2 1 0 2 2 2 0 Predicted ATPase of the ABC class Peripla_BP_6 PF13458.6 AAZ35093.1 - 6.4e-79 266.1 0.1 7.9e-79 265.8 0.1 1.1 1 0 0 1 1 1 1 Periplasmic binding protein T6SS_HCP PF05638.12 AAZ35095.1 - 6.1e-36 123.7 0.2 7.2e-36 123.4 0.2 1.1 1 0 0 1 1 1 1 Type VI secretion system effector, Hcp SNARE_assoc PF09335.11 AAZ35096.1 - 5.7e-22 78.5 3.4 5.7e-22 78.5 3.4 2.0 2 1 0 3 3 3 1 SNARE associated Golgi protein Osw5 PF17062.5 AAZ35096.1 - 0.04 14.0 0.6 0.04 14.0 0.6 2.0 2 1 1 3 3 3 0 Outer spore wall 5 Pam17 PF08566.10 AAZ35096.1 - 0.18 11.6 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 PAS_4 PF08448.10 AAZ35097.1 - 9.5e-26 90.2 0.0 3.9e-12 46.4 0.0 3.6 3 0 0 3 3 3 3 PAS fold Response_reg PF00072.24 AAZ35097.1 - 2.7e-19 69.4 0.0 5.8e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 AAZ35097.1 - 8.9e-19 68.1 0.0 1.5e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.25 AAZ35097.1 - 3e-18 65.9 0.0 4.4e-07 29.9 0.0 3.6 3 0 0 3 3 3 3 PAS fold PAS_3 PF08447.12 AAZ35097.1 - 6.4e-14 52.0 0.0 3.1e-09 37.0 0.0 3.2 4 0 0 4 4 4 2 PAS fold PAS_9 PF13426.7 AAZ35097.1 - 4.9e-10 39.6 0.0 0.0023 18.2 0.0 4.0 3 0 0 3 3 3 2 PAS domain HisKA PF00512.25 AAZ35097.1 - 8.9e-09 35.3 2.3 1.5e-08 34.5 0.1 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain FleQ PF06490.11 AAZ35097.1 - 0.0037 17.6 0.1 0.055 13.8 0.0 2.7 2 0 0 2 2 2 1 Flagellar regulatory protein FleQ Peptidase_M17 PF00883.21 AAZ35098.1 - 2.8e-129 430.9 0.0 3.6e-129 430.5 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 AAZ35098.1 - 7.9e-30 103.3 0.8 7.9e-30 103.3 0.8 2.2 2 0 0 2 2 2 1 Cytosol aminopeptidase family, N-terminal domain Aminotran_1_2 PF00155.21 AAZ35099.1 - 6.8e-79 265.7 0.0 7.6e-79 265.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II ILEI PF15711.5 AAZ35099.1 - 0.19 12.3 0.0 0.82 10.2 0.0 2.0 1 1 1 2 2 2 0 Interleukin-like EMT inducer EpuA PF11772.8 AAZ35100.1 - 0.061 13.0 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta TOBE PF03459.17 AAZ35101.1 - 7.4e-25 87.0 1.3 2.4e-14 53.3 0.4 2.2 2 0 0 2 2 2 2 TOBE domain TOBE_2 PF08402.10 AAZ35101.1 - 6.2e-07 29.5 0.2 0.0023 18.1 0.1 2.3 2 0 0 2 2 2 2 TOBE domain TOBE_3 PF12857.7 AAZ35101.1 - 9.9e-05 22.2 0.4 0.0062 16.4 0.3 2.4 2 0 0 2 2 2 1 TOBE-like domain Bac_luciferase PF00296.20 AAZ35102.1 - 1.8e-60 205.0 1.0 2.3e-60 204.7 1.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase NodS PF05401.11 AAZ35103.1 - 1.3e-16 60.8 0.0 1.8e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_25 PF13649.6 AAZ35103.1 - 3.3e-10 40.5 0.0 5.4e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAZ35103.1 - 1.2e-08 35.5 0.0 2e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAZ35103.1 - 4.6e-08 33.7 0.0 6.9e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAZ35103.1 - 5.5e-08 32.8 0.1 6.9e-08 32.5 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAZ35103.1 - 1.2e-06 28.4 0.0 1.6e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AAZ35103.1 - 1.9e-05 24.3 0.0 2.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CheR PF01739.18 AAZ35103.1 - 0.22 11.0 0.0 0.53 9.7 0.0 1.6 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Aldose_epim PF01263.20 AAZ35104.1 - 8.4e-30 104.1 0.0 9.4e-30 103.9 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase HrpJ PF07201.11 AAZ35105.1 - 4e-37 128.1 9.3 4e-37 128.1 9.3 2.3 3 0 0 3 3 3 1 HrpJ-like domain TyeA PF09059.10 AAZ35105.1 - 1.5e-05 25.0 0.1 5.7e-05 23.1 0.1 2.0 1 0 0 1 1 1 1 TyeA Trans_reg_C PF00486.28 AAZ35105.1 - 0.041 14.0 0.5 3.9 7.6 0.0 3.0 3 0 0 3 3 3 0 Transcriptional regulatory protein, C terminal AAA_assoc_2 PF16193.5 AAZ35105.1 - 0.12 12.7 0.4 0.38 11.1 0.1 2.0 2 0 0 2 2 2 0 AAA C-terminal domain CPSase_L_D2 PF02786.17 AAZ35106.1 - 5.3e-75 251.5 0.0 7.1e-75 251.1 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 AAZ35106.1 - 8.3e-42 142.2 0.0 2e-41 141.0 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 AAZ35106.1 - 8.2e-40 135.3 0.0 1.5e-39 134.4 0.0 1.4 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 AAZ35106.1 - 1.1e-06 28.3 0.0 4.6e-06 26.3 0.0 1.8 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 AAZ35106.1 - 1.8e-06 27.6 0.0 3.7e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 AAZ35106.1 - 7.4e-06 26.1 0.0 1.7e-05 25.0 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain LAL_C2 PF18603.1 AAZ35106.1 - 0.013 15.6 0.0 0.032 14.4 0.0 1.6 1 0 0 1 1 1 0 L-amino acid ligase C-terminal domain 2 RimK PF08443.11 AAZ35106.1 - 0.029 13.9 0.0 1.5 8.4 0.0 2.1 2 0 0 2 2 2 0 RimK-like ATP-grasp domain GARS_A PF01071.19 AAZ35106.1 - 0.069 12.9 0.0 0.24 11.1 0.0 1.8 1 1 1 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Phage_tail_S PF05069.13 AAZ35107.1 - 1.2e-10 41.4 3.8 2.2e-07 30.8 1.0 2.3 1 1 1 2 2 2 2 Phage virion morphogenesis family POP1 PF06978.11 AAZ35107.1 - 0.12 12.3 4.9 0.17 11.9 4.9 1.3 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 TilS PF09179.11 AAZ35107.1 - 2.8 8.5 7.2 5.2 7.6 0.6 3.0 3 0 0 3 3 3 0 TilS substrate binding domain Prenyltransf PF01255.19 AAZ35108.1 - 4.2e-76 255.4 0.0 4.8e-76 255.2 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase MCPsignal PF00015.21 AAZ35109.1 - 3.8e-42 144.0 34.4 1.6e-41 142.0 23.9 2.5 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain dCache_1 PF02743.18 AAZ35109.1 - 7.1e-31 107.9 0.0 7.1e-31 107.9 0.0 2.9 3 0 0 3 3 3 1 Cache domain HAMP PF00672.25 AAZ35109.1 - 3.8e-11 43.2 0.7 2.6e-09 37.3 0.1 3.4 3 0 0 3 3 3 1 HAMP domain dCache_2 PF08269.11 AAZ35109.1 - 8.7e-05 21.8 0.1 0.00054 19.2 0.0 2.3 2 1 0 2 2 2 1 Cache domain sCache_2 PF17200.4 AAZ35109.1 - 0.00023 21.0 0.2 0.0064 16.4 0.0 3.1 2 1 1 3 3 3 1 Single Cache domain 2 sCache_3_2 PF17203.4 AAZ35109.1 - 0.00032 20.9 2.0 0.045 13.9 0.0 3.4 2 2 1 3 3 3 1 Single cache domain 3 GAPES1 PF17155.4 AAZ35109.1 - 0.015 14.6 0.0 0.042 13.2 0.0 1.7 1 0 0 1 1 1 0 Gammaproteobacterial periplasmic sensor domain DUF1307 PF06998.11 AAZ35109.1 - 0.032 14.2 0.1 0.076 13.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1307) DUF5644 PF18712.1 AAZ35109.1 - 0.13 12.3 0.0 4.6 7.3 0.0 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5644) Arfaptin PF06456.13 AAZ35109.1 - 0.48 10.0 6.3 0.37 10.3 0.3 2.7 2 1 0 3 3 3 0 Arfaptin-like domain PLU-1 PF08429.11 AAZ35109.1 - 1.2 8.2 5.0 5.8 6.0 4.4 2.0 1 1 0 1 1 1 0 PLU-1-like protein BLOC1_2 PF10046.9 AAZ35109.1 - 1.8 8.9 16.9 1.5 9.2 0.3 4.0 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 AAZ35109.1 - 4.6 7.8 13.4 0.32 11.5 0.5 3.6 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein HEPN_Apea PF18739.1 AAZ35111.1 - 7e-05 23.2 0.0 0.00015 22.2 0.0 1.4 1 0 0 1 1 1 1 Apea-like HEPN Peptidase_M20 PF01546.28 AAZ35112.1 - 3.8e-32 111.7 0.0 4.9e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AAZ35112.1 - 7e-19 67.8 0.0 1.5e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 AAZ35112.1 - 1.6e-08 34.5 0.0 2.8e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.14 AAZ35112.1 - 0.00072 18.7 0.0 0.01 14.9 0.0 2.4 2 1 0 2 2 2 1 M42 glutamyl aminopeptidase Anthrax_toxA PF03497.16 AAZ35112.1 - 0.19 11.9 0.0 0.43 10.7 0.0 1.5 2 0 0 2 2 2 0 Anthrax toxin LF subunit FMN_bind_2 PF04299.12 AAZ35113.1 - 5.6e-61 205.1 0.0 7e-61 204.8 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain Pyridox_ox_2 PF12900.7 AAZ35113.1 - 0.11 12.5 0.0 0.17 11.8 0.0 1.5 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase AMP-binding PF00501.28 AAZ35114.1 - 2.8e-16 59.1 0.2 4.4e-09 35.4 0.0 3.1 1 1 2 3 3 3 3 AMP-binding enzyme FabA PF07977.13 AAZ35114.1 - 6.7e-08 32.3 0.0 2.2e-07 30.6 0.0 1.9 1 1 0 1 1 1 1 FabA-like domain AMP-binding_C PF13193.6 AAZ35114.1 - 0.00079 20.4 0.0 0.0015 19.4 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TPR_2 PF07719.17 AAZ35115.1 - 3.2e-07 29.9 3.5 0.018 15.1 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 AAZ35115.1 - 6.6e-06 26.7 5.2 0.0004 21.0 1.6 3.6 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 AAZ35115.1 - 2.7e-05 24.3 5.1 0.12 12.7 0.1 3.2 3 1 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 AAZ35115.1 - 7.4e-05 22.9 0.1 0.0012 19.0 0.0 2.4 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 AAZ35115.1 - 7.4e-05 23.2 11.5 0.0042 17.6 0.3 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 AAZ35115.1 - 0.00019 21.2 0.6 1.4 9.1 0.0 3.2 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 AAZ35115.1 - 0.00037 20.2 0.2 1.5 8.8 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 AAZ35115.1 - 0.00084 20.0 0.3 0.00084 20.0 0.3 5.0 2 1 3 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 AAZ35115.1 - 0.0096 15.8 5.3 0.27 11.1 0.1 3.2 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 AAZ35115.1 - 0.017 15.5 0.5 7.3 7.2 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 AAZ35115.1 - 0.043 14.1 0.0 2.2 8.7 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 AAZ35115.1 - 0.061 14.0 7.1 0.22 12.2 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 AAZ35115.1 - 1.1 9.7 9.9 0.53 10.6 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 AAZ35115.1 - 3.8 8.3 11.4 7.3 7.5 0.1 4.3 4 1 1 5 5 5 0 Tetratricopeptide repeat UreF PF01730.16 AAZ35116.1 - 1.6e-37 129.1 11.0 2.5e-37 128.4 11.0 1.3 1 0 0 1 1 1 1 UreF DAGK_cat PF00781.24 AAZ35116.1 - 0.23 11.1 0.2 0.51 10.0 0.0 1.6 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain PrgI PF12666.7 AAZ35117.1 - 0.12 13.1 7.5 0.35 11.6 0.4 2.3 2 0 0 2 2 2 0 PrgI family protein Halogen_Hydrol PF10112.9 AAZ35117.1 - 2.1 8.3 7.9 2 8.4 1.2 2.1 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein OsmC PF02566.19 AAZ35118.1 - 2.4e-19 69.7 0.0 4.7e-18 65.5 0.0 2.0 2 0 0 2 2 2 1 OsmC-like protein AMP-binding PF00501.28 AAZ35119.1 - 4.8e-69 233.0 0.2 3.9e-68 230.0 0.2 2.0 1 1 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 AAZ35119.1 - 1e-10 41.8 0.1 2.4e-10 40.6 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 AAZ35119.1 - 2.8e-05 25.0 0.0 6e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Methyltransf_4 PF02390.17 AAZ35120.1 - 1.8e-53 180.5 0.0 2.2e-53 180.3 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 AAZ35120.1 - 0.012 16.3 0.0 0.017 15.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.17 AAZ35120.1 - 0.02 14.1 0.0 0.032 13.4 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase CRS1_YhbY PF01985.21 AAZ35121.1 - 1.6e-17 63.4 0.1 1.9e-17 63.2 0.1 1.1 1 0 0 1 1 1 1 CRS1 / YhbY (CRM) domain Fimbrial PF00419.20 AAZ35123.1 - 2.6e-11 44.0 5.6 3.2e-11 43.7 5.6 1.2 1 0 0 1 1 1 1 Fimbrial protein DUF2574 PF10836.8 AAZ35123.1 - 0.0037 17.1 0.1 0.0082 16.0 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2574) TetR_N PF00440.23 AAZ35124.1 - 8.1e-10 38.3 0.1 2e-09 37.1 0.1 1.7 1 1 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 AAZ35124.1 - 0.00026 21.3 0.3 0.00061 20.1 0.4 1.7 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_13 PF16925.5 AAZ35124.1 - 0.1 12.5 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain A_deaminase PF00962.22 AAZ35126.1 - 7.7e-69 232.5 0.0 9.4e-69 232.2 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase SBF_like PF13593.6 AAZ35127.1 - 3.9e-102 341.7 23.1 4.5e-102 341.6 23.1 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) CcmD PF04995.14 AAZ35127.1 - 1.1 9.5 5.8 0.95 9.6 0.7 3.5 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) DUF3278 PF11683.8 AAZ35127.1 - 4.8 7.3 6.5 1.2 9.3 0.5 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3278) DPRP PF04244.13 AAZ35128.1 - 1e-81 274.1 0.0 1.5e-81 273.5 0.0 1.3 1 0 0 1 1 1 1 Deoxyribodipyrimidine photo-lyase-related protein Cupin_3 PF05899.12 AAZ35129.1 - 4.1e-09 36.0 0.0 5.8e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 AAZ35129.1 - 0.00041 20.0 0.0 0.0011 18.6 0.0 1.6 2 0 0 2 2 2 1 Cupin domain ADH_zinc_N_2 PF13602.6 AAZ35130.1 - 3.7e-09 37.7 0.0 4.1e-09 37.6 0.0 1.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DNA_pol_A PF00476.20 AAZ35132.1 - 5.4e-27 94.8 0.0 7.9e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A FadR_C PF07840.12 AAZ35132.1 - 0.062 13.2 0.2 0.15 11.9 0.2 1.8 1 0 0 1 1 1 0 FadR C-terminal domain Sigma54_activat PF00158.26 AAZ35133.1 - 6.4e-65 218.0 0.0 9.7e-65 217.4 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Response_reg PF00072.24 AAZ35133.1 - 9.7e-32 109.5 0.0 2.7e-31 108.0 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain Sigma54_activ_2 PF14532.6 AAZ35133.1 - 5.7e-21 75.1 0.0 1.5e-20 73.8 0.0 1.7 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 AAZ35133.1 - 3.4e-06 26.7 0.3 1e-05 25.2 0.3 1.9 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 AAZ35133.1 - 4.8e-06 26.6 0.0 0.00015 21.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) FleQ PF06490.11 AAZ35133.1 - 0.00066 20.0 0.0 0.0018 18.7 0.0 1.8 1 0 0 1 1 1 1 Flagellar regulatory protein FleQ AAA PF00004.29 AAZ35133.1 - 0.00077 19.9 0.0 0.0021 18.5 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 AAZ35133.1 - 0.0049 16.3 0.2 0.8 9.0 0.0 2.9 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 AAZ35133.1 - 0.014 15.5 0.0 0.028 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) MCM PF00493.23 AAZ35133.1 - 0.029 13.5 0.0 0.18 10.9 0.0 1.9 2 0 0 2 2 2 0 MCM P-loop domain FTSW_RODA_SPOVE PF01098.19 AAZ35134.1 - 3.8e-111 371.5 25.5 4.7e-111 371.3 25.5 1.0 1 0 0 1 1 1 1 Cell cycle protein DUF543 PF04418.12 AAZ35134.1 - 0.091 12.8 0.2 0.37 10.8 0.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF543) Bac_luciferase PF00296.20 AAZ35135.1 - 4.7e-79 266.1 5.0 6.2e-79 265.7 5.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Cob_adeno_trans PF01923.18 AAZ35138.1 - 9.3e-52 175.5 0.0 1.1e-51 175.3 0.0 1.0 1 0 0 1 1 1 1 Cobalamin adenosyltransferase Resolvase PF00239.21 AAZ35139.1 - 4e-24 85.4 0.0 6.8e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Resolvase, N terminal domain Recombinase PF07508.13 AAZ35139.1 - 1.4e-18 67.2 0.0 2.6e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Recombinase P-II PF00543.22 AAZ35140.1 - 0.0086 16.7 0.0 0.012 16.2 0.0 1.2 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II CutA1 PF03091.15 AAZ35140.1 - 0.012 15.5 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 CutA1 divalent ion tolerance protein DUF1424 PF07232.11 AAZ35140.1 - 0.046 12.7 0.0 0.05 12.6 0.0 1.1 1 0 0 1 1 1 0 Putative rep protein (DUF1424) ABC_tran PF00005.27 AAZ35142.1 - 5.5e-33 114.4 0.0 7.5e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAZ35142.1 - 6.9e-11 42.5 1.7 0.00019 21.4 0.2 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAZ35142.1 - 2.4e-08 33.7 0.0 5.2e-07 29.3 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 AAZ35142.1 - 2.9e-07 30.5 0.0 7.5e-06 25.9 0.0 2.0 1 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 AAZ35142.1 - 9.3e-06 25.3 0.0 1.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AAZ35142.1 - 1e-05 26.0 0.4 2.6e-05 24.7 0.4 1.7 1 1 0 1 1 1 1 AAA ATPase domain DUF2813 PF11398.8 AAZ35142.1 - 0.0001 21.7 0.0 0.00016 21.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2813) RsgA_GTPase PF03193.16 AAZ35142.1 - 0.00022 21.2 0.0 0.00039 20.4 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_5 PF07728.14 AAZ35142.1 - 0.00045 20.2 0.2 0.0025 17.8 0.1 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 AAZ35142.1 - 0.00047 20.1 0.5 0.0017 18.3 0.1 2.0 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.6 AAZ35142.1 - 0.00055 19.6 0.8 0.0016 18.1 0.8 2.1 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.22 AAZ35142.1 - 0.00064 19.4 0.1 0.0012 18.5 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_33 PF13671.6 AAZ35142.1 - 0.00085 19.5 0.2 0.0025 18.0 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 AAZ35142.1 - 0.0023 18.4 0.1 0.0066 16.9 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 AAZ35142.1 - 0.0023 18.2 0.3 0.0073 16.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 AAZ35142.1 - 0.0025 17.6 0.3 0.0054 16.5 0.3 1.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 AAZ35142.1 - 0.0036 17.3 0.0 0.016 15.3 0.0 2.0 2 1 1 3 3 3 1 AAA domain Mg_chelatase PF01078.21 AAZ35142.1 - 0.004 16.6 0.1 0.017 14.5 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 AAZ35142.1 - 0.0045 17.3 0.4 0.032 14.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 AAZ35142.1 - 0.0057 16.0 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin ABC_ATPase PF09818.9 AAZ35142.1 - 0.0079 15.0 0.1 0.48 9.2 0.0 2.6 2 1 0 2 2 2 1 Predicted ATPase of the ABC class Rad17 PF03215.15 AAZ35142.1 - 0.0086 16.0 0.2 0.024 14.6 0.0 1.8 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_18 PF13238.6 AAZ35142.1 - 0.014 16.0 0.2 0.17 12.4 0.2 2.6 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AAZ35142.1 - 0.017 15.6 0.0 0.026 15.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 AAZ35142.1 - 0.023 15.1 0.0 0.059 13.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ATP-synt_ab PF00006.25 AAZ35142.1 - 0.033 13.8 0.0 0.16 11.6 0.0 1.9 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_27 PF13514.6 AAZ35142.1 - 0.04 13.5 0.0 0.079 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 AAZ35142.1 - 0.041 13.8 0.0 0.054 13.4 0.0 1.4 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea DUF815 PF05673.13 AAZ35142.1 - 0.043 13.0 0.0 0.075 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) cobW PF02492.19 AAZ35142.1 - 0.052 13.1 0.1 0.092 12.3 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.18 AAZ35142.1 - 0.061 13.0 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase G-alpha PF00503.20 AAZ35142.1 - 0.069 12.3 0.1 0.11 11.6 0.1 1.5 1 1 0 1 1 1 0 G-protein alpha subunit TrwB_AAD_bind PF10412.9 AAZ35142.1 - 0.069 12.0 0.3 4.9 6.0 0.0 2.3 1 1 1 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain CbiA PF01656.23 AAZ35142.1 - 0.075 13.1 0.1 0.098 12.7 0.1 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 AAZ35142.1 - 0.13 11.7 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Adeno_IVa2 PF02456.15 AAZ35142.1 - 0.17 10.7 0.0 0.28 9.9 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein TMP-TENI PF02581.17 AAZ35143.1 - 1.2e-56 191.0 0.0 1.4e-56 190.7 0.0 1.1 1 0 0 1 1 1 1 Thiamine monophosphate synthase FMN_dh PF01070.18 AAZ35143.1 - 0.04 12.9 0.0 0.092 11.8 0.0 1.5 1 1 0 1 1 1 0 FMN-dependent dehydrogenase His_biosynth PF00977.21 AAZ35143.1 - 0.099 12.1 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 AAZ35143.1 - 0.1 11.9 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Dus PF01207.17 AAZ35143.1 - 0.2 10.7 0.0 0.62 9.1 0.0 1.7 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) Branch_AA_trans PF05525.13 AAZ35144.1 - 1.7e-152 508.2 34.0 2e-152 508.0 34.0 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport protein L6_membrane PF05805.12 AAZ35144.1 - 0.026 14.1 5.5 0.05 13.2 4.4 2.1 1 1 0 1 1 1 0 L6 membrane protein Trns_repr_metal PF02583.17 AAZ35145.1 - 8e-23 80.6 0.7 8.6e-23 80.5 0.7 1.1 1 0 0 1 1 1 1 Metal-sensitive transcriptional repressor HTH_50 PF18024.1 AAZ35145.1 - 0.031 13.9 1.2 0.067 12.8 0.4 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain SBP_bac_8 PF13416.6 AAZ35146.1 - 1e-30 107.5 0.6 1.3e-30 107.2 0.6 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AAZ35146.1 - 7.1e-20 71.4 0.1 1.1e-19 70.9 0.1 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AAZ35146.1 - 4e-14 53.3 1.2 6.7e-14 52.6 1.2 1.4 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein Lipoprotein_8 PF02030.15 AAZ35146.1 - 0.00037 19.3 0.0 0.49 9.1 0.0 2.2 2 0 0 2 2 2 2 Hypothetical lipoprotein (MG045 family) SBP_bac_11 PF13531.6 AAZ35146.1 - 0.0016 18.2 0.0 0.0053 16.5 0.0 1.7 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein IU_nuc_hydro PF01156.19 AAZ35147.1 - 6.2e-81 272.3 0.1 7.3e-81 272.1 0.1 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase MFS_1 PF07690.16 AAZ35148.1 - 4e-18 65.5 34.0 4e-18 65.5 34.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Bacillus_HBL PF05791.11 AAZ35148.1 - 0.17 11.7 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) WTF PF03303.13 AAZ35148.1 - 1.3 8.7 3.6 8.4 6.0 0.8 2.3 2 0 0 2 2 2 0 WTF protein Pyr_redox_2 PF07992.14 AAZ35149.1 - 2.6e-10 40.0 0.0 4.1e-08 32.8 0.0 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AAZ35149.1 - 8.1e-06 25.7 0.2 1.3e-05 25.0 0.2 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 AAZ35149.1 - 8.5e-06 25.8 0.4 0.00055 19.9 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 AAZ35149.1 - 0.00023 20.3 0.3 0.002 17.2 0.4 2.1 1 1 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 AAZ35149.1 - 0.0037 17.5 0.4 0.011 15.9 0.4 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 AAZ35149.1 - 0.0049 15.6 0.1 0.0094 14.7 0.0 1.5 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.14 AAZ35149.1 - 0.0052 15.7 0.3 0.0085 15.0 0.2 1.4 1 1 0 1 1 1 1 Tryptophan halogenase FAD_binding_3 PF01494.19 AAZ35149.1 - 0.027 13.7 0.0 0.12 11.5 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.6 AAZ35149.1 - 0.072 13.5 0.0 0.17 12.3 0.0 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox PF00070.27 AAZ35149.1 - 0.14 12.7 0.0 0.65 10.6 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AAZ35149.1 - 1.1 8.2 3.7 1.6 7.7 3.6 1.6 1 1 0 1 1 1 0 FAD binding domain DLH PF01738.18 AAZ35150.1 - 1.3e-45 155.6 0.3 1.5e-45 155.5 0.3 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 AAZ35150.1 - 3.5e-08 33.2 0.5 0.0033 16.9 0.1 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family BAAT_C PF08840.11 AAZ35150.1 - 4.9e-07 29.9 0.2 0.0012 18.8 0.0 2.2 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 AAZ35150.1 - 1.1e-06 28.1 0.1 0.00039 19.7 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 AAZ35150.1 - 0.0001 22.2 0.0 0.00015 21.7 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 AAZ35150.1 - 0.00064 19.4 0.0 0.0012 18.6 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.12 AAZ35150.1 - 0.004 15.9 0.1 0.015 14.0 0.1 1.8 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 AAZ35150.1 - 0.0063 17.2 0.1 0.01 16.4 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DAP3 PF10236.9 AAZ35150.1 - 0.02 14.1 0.0 0.16 11.1 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 TetR_N PF00440.23 AAZ35151.1 - 6.1e-12 45.1 1.5 1.3e-11 44.1 0.9 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_27 PF17935.1 AAZ35151.1 - 1.6e-10 41.0 0.0 3.1e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_24 PF17932.1 AAZ35151.1 - 2.2e-05 24.7 0.1 3.7e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain Herpes_IE68 PF02479.16 AAZ35151.1 - 0.049 13.3 0.2 0.18 11.4 0.0 1.9 2 1 0 2 2 2 0 Herpesvirus immediate early protein TetR_C_29 PF17938.1 AAZ35151.1 - 0.087 12.9 0.0 0.17 12.0 0.0 1.6 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Amidohydro_1 PF01979.20 AAZ35151.1 - 0.12 11.6 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Amidohydrolase family Aldedh PF00171.22 AAZ35153.1 - 2.2e-177 590.2 0.3 2.4e-177 590.1 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Methyltransf_31 PF13847.6 AAZ35154.1 - 3.9e-18 65.7 0.0 5.1e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AAZ35154.1 - 5.4e-18 65.1 0.0 2.1e-17 63.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain PrmC_N PF17827.1 AAZ35154.1 - 1e-16 61.3 0.7 5.8e-16 58.8 0.2 2.4 3 0 0 3 3 2 1 PrmC N-terminal domain Methyltransf_25 PF13649.6 AAZ35154.1 - 4.6e-10 40.1 0.0 7.6e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAZ35154.1 - 4.8e-09 36.3 0.0 9.9e-09 35.2 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 AAZ35154.1 - 4.6e-08 32.9 0.0 6.5e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_12 PF08242.12 AAZ35154.1 - 2.1e-07 31.6 0.0 3.7e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 AAZ35154.1 - 2.5e-07 30.4 0.0 3.8e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 AAZ35154.1 - 3.6e-07 30.7 0.0 6.6e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.15 AAZ35154.1 - 2.6e-06 26.9 0.0 3.7e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G UPF0020 PF01170.18 AAZ35154.1 - 8.2e-06 25.6 0.0 1.2e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 TehB PF03848.14 AAZ35154.1 - 2.2e-05 24.0 0.0 3.2e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_16 PF10294.9 AAZ35154.1 - 0.0001 22.1 0.0 0.00015 21.5 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PCMT PF01135.19 AAZ35154.1 - 0.00015 21.6 0.0 0.00022 21.1 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 AAZ35154.1 - 0.00049 20.1 0.0 0.0017 18.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 AAZ35154.1 - 0.0013 18.2 0.0 0.0021 17.6 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Rsm22 PF09243.10 AAZ35154.1 - 0.012 14.9 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_32 PF13679.6 AAZ35154.1 - 0.012 15.5 0.0 0.017 15.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 AAZ35154.1 - 0.014 14.6 0.0 0.019 14.1 0.0 1.1 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_10 PF05971.12 AAZ35154.1 - 0.022 14.1 0.0 0.03 13.6 0.0 1.1 1 0 0 1 1 1 0 RNA methyltransferase N6_Mtase PF02384.16 AAZ35154.1 - 0.072 12.4 0.0 0.089 12.0 0.0 1.1 1 0 0 1 1 1 0 N-6 DNA Methylase NodS PF05401.11 AAZ35154.1 - 0.13 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Eco57I PF07669.11 AAZ35154.1 - 0.19 12.3 0.0 0.33 11.5 0.0 1.3 1 0 0 1 1 1 0 Eco57I restriction-modification methylase Met_10 PF02475.16 AAZ35154.1 - 0.23 11.2 0.0 0.32 10.7 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Ubie_methyltran PF01209.18 AAZ35154.1 - 0.29 10.4 0.0 0.4 10.0 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family TPR_19 PF14559.6 AAZ35155.1 - 5e-11 42.9 5.7 0.00078 19.9 0.6 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 AAZ35155.1 - 6.6e-05 23.4 10.0 1.7 9.7 0.4 5.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 AAZ35155.1 - 0.0015 18.7 3.1 12 6.2 0.1 4.2 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 AAZ35155.1 - 0.0069 16.9 12.3 0.11 13.1 1.3 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 AAZ35155.1 - 0.011 16.3 12.0 2 9.1 2.2 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 AAZ35155.1 - 0.013 15.6 0.1 37 4.9 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 AAZ35155.1 - 0.018 15.1 1.4 1.8 8.9 0.2 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 AAZ35155.1 - 0.07 13.0 6.3 3 7.8 0.5 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 AAZ35155.1 - 0.53 11.0 2.2 5 8.0 0.4 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DGOK PF05035.12 AAZ35156.1 - 8.1e-102 339.9 0.3 9.3e-102 339.8 0.3 1.0 1 0 0 1 1 1 1 2-keto-3-deoxy-galactonokinase Mobilization_B PF17511.2 AAZ35156.1 - 0.1 13.0 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Mobilization protein B EamA PF00892.20 AAZ35157.1 - 2.7e-37 128.0 37.9 1.5e-18 67.3 16.9 2.0 2 0 0 2 2 2 2 EamA-like transporter family G0-G1_switch_2 PF15103.6 AAZ35157.1 - 0.024 15.1 1.5 7 7.1 0.0 2.4 2 0 0 2 2 2 0 G0/G1 switch protein 2 SRAP PF02586.14 AAZ35158.1 - 2.7e-36 125.2 0.0 3.1e-36 125.0 0.0 1.0 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) DUF3102 PF11300.8 AAZ35159.1 - 0.021 15.1 0.2 0.63 10.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3102) Matrilin_ccoil PF10393.9 AAZ35159.1 - 0.63 10.0 3.3 5.4 7.0 0.1 3.1 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF1664 PF07889.12 AAZ35159.1 - 0.65 10.0 24.7 6 6.9 0.7 5.0 3 2 1 5 5 5 0 Protein of unknown function (DUF1664) Ribosomal_L29 PF00831.23 AAZ35159.1 - 2 8.5 8.1 11 6.1 1.1 3.5 2 0 0 2 2 2 0 Ribosomal L29 protein DUF1993 PF09351.10 AAZ35159.1 - 2.7 8.1 9.5 0.28 11.3 0.4 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF1993) HALZ PF02183.18 AAZ35159.1 - 9.7 6.5 14.1 1.9 8.8 3.4 4.4 4 0 0 4 4 4 0 Homeobox associated leucine zipper HSP70 PF00012.20 AAZ35160.1 - 0.06 11.5 0.0 0.077 11.2 0.0 1.1 1 0 0 1 1 1 0 Hsp70 protein Inh PF02974.14 AAZ35161.1 - 6.2e-17 61.5 0.0 7.6e-17 61.2 0.0 1.1 1 0 0 1 1 1 1 Protease inhibitor Inh PAS_8 PF13188.7 AAZ35161.1 - 0.16 12.0 0.0 0.34 11.0 0.0 1.6 2 0 0 2 2 2 0 PAS domain MotA_ExbB PF01618.16 AAZ35162.1 - 1.4e-34 118.6 0.5 1.9e-34 118.1 0.5 1.2 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family Chlorosome_CsmC PF11098.8 AAZ35162.1 - 0.065 13.2 0.1 0.094 12.7 0.1 1.3 1 0 0 1 1 1 0 Chlorosome envelope protein C Aminotran_1_2 PF00155.21 AAZ35163.1 - 5.5e-55 187.0 0.0 6.2e-55 186.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 AAZ35163.1 - 0.059 12.6 0.0 0.49 9.6 0.0 2.1 2 0 0 2 2 2 0 Beta-eliminating lyase LTXXQ PF07813.12 AAZ35164.1 - 0.00022 21.9 16.9 0.00071 20.3 10.3 2.8 2 1 0 2 2 2 1 LTXXQ motif family protein Metal_resist PF13801.6 AAZ35164.1 - 0.22 11.7 21.1 0.67 10.2 12.8 3.3 1 1 1 2 2 2 0 Heavy-metal resistance DUF1266 PF06889.11 AAZ35164.1 - 0.67 10.0 6.1 0.84 9.7 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) Rota_VP2 PF05087.12 AAZ35164.1 - 0.69 8.0 2.5 0.85 7.7 2.5 1.0 1 0 0 1 1 1 0 Rotavirus VP2 protein FUSC PF04632.12 AAZ35164.1 - 0.87 8.0 4.1 0.97 7.9 4.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF612 PF04747.12 AAZ35164.1 - 1.7 7.7 12.7 2 7.4 12.7 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF612 Aspzincin_M35 PF14521.6 AAZ35165.1 - 0.00077 20.0 0.0 0.0017 18.9 0.0 1.5 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase LysR_substrate PF03466.20 AAZ35166.1 - 1.4e-26 93.1 0.9 1.8e-26 92.8 0.9 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ35166.1 - 1.4e-15 57.0 0.2 3.6e-15 55.6 0.2 1.8 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family SSB PF00436.25 AAZ35167.1 - 2.6e-38 130.2 0.5 3.3e-38 129.9 0.5 1.2 1 0 0 1 1 1 1 Single-strand binding protein family CCDC53 PF10152.9 AAZ35167.1 - 0.072 13.5 2.5 0.078 13.4 2.5 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF1294 PF06961.13 AAZ35168.1 - 7.9e-23 80.5 0.1 1.7e-22 79.4 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1294) MFS_1 PF07690.16 AAZ35168.1 - 0.022 13.7 2.5 0.025 13.5 2.5 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily Transposase_mut PF00872.18 AAZ35169.1 - 2.7e-117 391.9 0.0 3.3e-117 391.6 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ35169.1 - 7.8e-05 23.0 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain DUF4844 PF16133.5 AAZ35169.1 - 0.23 12.0 0.0 0.55 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) TP_methylase PF00590.20 AAZ35170.1 - 2.1e-56 191.2 0.3 3.2e-56 190.6 0.3 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 AAZ35170.1 - 1.4e-27 96.1 0.1 1.2e-26 93.2 0.0 2.2 2 0 0 2 2 2 1 Putative NAD(P)-binding CysG_dimeriser PF10414.9 AAZ35170.1 - 1.4e-20 72.7 2.8 3.8e-20 71.3 2.8 1.8 1 0 0 1 1 1 1 Sirohaem synthase dimerisation region Sirohm_synth_M PF14824.6 AAZ35170.1 - 1.4e-08 34.0 0.2 8.1e-08 31.6 0.1 2.2 2 0 0 2 2 2 1 Sirohaem biosynthesis protein central Radical_SAM PF04055.21 AAZ35170.1 - 0.0063 16.9 0.0 0.04 14.3 0.0 2.1 2 0 0 2 2 2 1 Radical SAM superfamily FCD PF07729.12 AAZ35171.1 - 2.7e-18 66.6 6.8 2.7e-18 66.6 6.8 1.7 2 0 0 2 2 2 1 FCD domain GntR PF00392.21 AAZ35171.1 - 2.1e-16 59.3 1.0 6.1e-16 57.8 1.0 1.9 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_28 PF13518.6 AAZ35171.1 - 0.013 15.6 0.1 0.038 14.1 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain TFIIE_alpha PF02002.17 AAZ35171.1 - 0.021 14.7 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 TFIIE alpha subunit HTH_11 PF08279.12 AAZ35171.1 - 0.031 14.2 0.0 0.07 13.1 0.0 1.6 1 0 0 1 1 1 0 HTH domain Rrf2 PF02082.20 AAZ35171.1 - 0.11 12.8 0.1 0.5 10.8 0.0 2.1 2 0 0 2 2 2 0 Transcriptional regulator RmlD_sub_bind PF04321.17 AAZ35172.1 - 1e-108 362.8 0.0 1.1e-108 362.7 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 AAZ35172.1 - 5.2e-17 62.1 0.0 1.3e-16 60.8 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AAZ35172.1 - 2.7e-10 40.2 0.0 6.3e-10 39.0 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 AAZ35172.1 - 1.4e-05 24.4 0.0 8.7e-05 21.8 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 AAZ35172.1 - 0.00031 20.0 0.0 0.0005 19.3 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein PqqA PF08042.11 AAZ35173.1 - 2.5e-11 43.1 0.2 2.7e-11 43.0 0.2 1.1 1 0 0 1 1 1 1 PqqA family BPD_transp_1 PF00528.22 AAZ35174.1 - 1.2e-24 87.1 16.9 1.2e-24 87.1 16.9 1.8 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Adenylate_cycl PF01295.18 AAZ35176.1 - 8.4e-121 404.5 0.0 3.2e-120 402.6 0.0 1.7 1 1 0 1 1 1 1 Adenylate cyclase, class-I Adenyl_cycl_N PF12633.7 AAZ35176.1 - 4.3e-77 258.5 0.0 6.9e-77 257.9 0.0 1.3 1 0 0 1 1 1 1 Adenylate cyclase NT domain Mur_ligase_M PF08245.12 AAZ35177.1 - 4.6e-53 180.1 0.0 6.5e-53 179.6 0.0 1.2 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 AAZ35177.1 - 1.3e-22 79.9 0.0 1.2e-21 76.7 0.0 2.4 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain Mur_ligase PF01225.25 AAZ35177.1 - 6.9e-14 51.9 0.2 6.9e-13 48.7 0.0 2.6 3 0 0 3 3 3 1 Mur ligase family, catalytic domain Arg_repressor_C PF02863.18 AAZ35177.1 - 0.068 13.0 0.4 9.4 6.2 0.0 2.5 2 0 0 2 2 2 0 Arginine repressor, C-terminal domain DUF4667 PF15700.5 AAZ35178.1 - 0.052 13.7 4.1 0.053 13.6 4.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) LGT PF01790.18 AAZ35179.1 - 1.3e-81 273.4 10.9 1.5e-81 273.3 10.9 1.0 1 0 0 1 1 1 1 Prolipoprotein diacylglyceryl transferase DUF4381 PF14316.6 AAZ35179.1 - 5.2 7.3 6.8 9.9 6.4 1.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF4124 PF13511.6 AAZ35180.1 - 5e-05 23.5 1.2 6.5e-05 23.2 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4124) DUF2780 PF11075.8 AAZ35181.1 - 2.3e-47 161.4 16.9 2.8e-47 161.1 16.9 1.1 1 0 0 1 1 1 1 Protein of unknown function VcgC/VcgE (DUF2780) T6SS_TssF PF05947.12 AAZ35182.1 - 8.5e-215 714.8 0.0 9.5e-215 714.7 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system, TssF Glyoxalase_3 PF13468.6 AAZ35183.1 - 1.3e-23 84.0 0.3 1.2e-22 80.9 0.0 1.9 2 0 0 2 2 2 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 AAZ35183.1 - 0.0001 22.5 0.0 0.00025 21.3 0.0 1.6 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 AAZ35183.1 - 0.038 14.2 0.1 1.2 9.3 0.0 2.5 2 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ABC_tran PF00005.27 AAZ35184.1 - 2.6e-52 177.0 0.5 1.8e-28 99.7 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 AAZ35184.1 - 6.6e-14 51.7 11.3 1.2e-11 44.5 6.2 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 AAZ35184.1 - 3.3e-12 46.8 11.3 0.0017 18.2 0.1 4.4 2 2 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAZ35184.1 - 7.4e-06 25.6 5.1 2.3 7.6 0.1 4.2 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 AAZ35184.1 - 1.6e-05 25.0 0.3 0.048 13.8 0.1 3.2 3 1 0 3 3 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 AAZ35184.1 - 0.00012 21.7 3.2 0.14 11.9 0.1 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain MeaB PF03308.16 AAZ35184.1 - 0.0011 18.0 0.2 1.2 8.0 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB DLIC PF05783.11 AAZ35184.1 - 0.0018 17.2 0.8 0.27 10.0 0.0 2.5 3 0 0 3 3 3 1 Dynein light intermediate chain (DLIC) RsgA_GTPase PF03193.16 AAZ35184.1 - 0.0028 17.6 0.5 0.23 11.3 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase SbcCD_C PF13558.6 AAZ35184.1 - 0.0034 17.6 0.9 2.4 8.5 0.0 3.9 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 AAZ35184.1 - 0.0041 17.7 0.1 1.6 9.3 0.0 3.0 2 1 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 AAZ35184.1 - 0.0081 16.2 4.0 0.54 10.3 0.0 3.4 3 2 0 3 3 3 1 Dynamin family AAA_22 PF13401.6 AAZ35184.1 - 0.016 15.5 1.2 1.8 8.8 0.1 3.1 2 2 0 2 2 2 0 AAA domain AAA_24 PF13479.6 AAZ35184.1 - 0.02 14.6 0.1 5.1 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 AAZ35184.1 - 0.031 14.4 3.6 4.3 7.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 AAZ35184.1 - 0.033 14.4 0.1 5.9 7.1 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 AAZ35184.1 - 0.033 14.7 13.6 0.31 11.5 0.1 3.3 2 1 0 2 2 2 0 AAA domain Arf PF00025.21 AAZ35184.1 - 0.034 13.6 0.0 2.2 7.7 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family NB-ARC PF00931.22 AAZ35184.1 - 0.037 13.2 0.4 2.8 7.1 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_28 PF13521.6 AAZ35184.1 - 0.11 12.7 5.7 0.94 9.7 0.0 3.3 3 1 0 3 3 2 0 AAA domain cobW PF02492.19 AAZ35184.1 - 0.12 12.0 0.6 11 5.6 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 AAZ35184.1 - 0.14 11.8 1.6 14 5.3 0.0 2.7 2 1 1 3 3 3 0 AAA ATPase domain AAA_17 PF13207.6 AAZ35184.1 - 0.16 12.4 1.2 19 5.7 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_14 PF13173.6 AAZ35184.1 - 0.17 11.9 0.0 22 5.1 0.0 2.9 3 0 0 3 3 2 0 AAA domain FeoB_N PF02421.18 AAZ35184.1 - 0.26 10.8 0.5 18 4.9 0.0 3.1 3 0 0 3 3 3 0 Ferrous iron transport protein B AAA_16 PF13191.6 AAZ35184.1 - 0.77 10.1 8.1 22 5.4 0.0 3.3 2 1 1 3 3 3 0 AAA ATPase domain NACHT PF05729.12 AAZ35184.1 - 1.5 8.7 4.0 24 4.8 0.1 2.4 2 0 0 2 2 2 0 NACHT domain MRP-L46 PF11788.8 AAZ35184.1 - 2.1 9.1 6.0 0.51 11.1 2.7 1.6 2 0 0 2 2 1 0 39S mitochondrial ribosomal protein L46 AAA_13 PF13166.6 AAZ35184.1 - 2.4 6.7 8.3 9.2 4.8 0.0 3.4 3 1 1 4 4 4 0 AAA domain CN_hydrolase PF00795.22 AAZ35185.1 - 6.7e-52 176.4 0.1 7.5e-52 176.2 0.1 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase SBP_bac_3 PF00497.20 AAZ35186.1 - 4.9e-23 81.7 0.0 7.1e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 HisKA_3 PF07730.13 AAZ35186.1 - 3.8e-13 49.8 0.3 3.8e-13 49.8 0.3 2.9 3 0 0 3 3 2 1 Histidine kinase PAS PF00989.25 AAZ35186.1 - 1.5e-07 31.4 0.0 5.1e-07 29.7 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 AAZ35186.1 - 2.9e-07 30.7 0.1 1.2e-06 28.7 0.1 2.2 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AAZ35186.1 - 3.5e-07 30.4 0.0 7.3e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 PAS domain HATPase_c PF02518.26 AAZ35186.1 - 2.7e-06 27.9 0.0 2.6e-05 24.7 0.0 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.7 AAZ35186.1 - 3.9e-06 26.7 0.0 1.3e-05 25.1 0.0 1.9 1 0 0 1 1 1 1 PAS domain HATPase_c_2 PF13581.6 AAZ35186.1 - 2.5e-05 24.2 0.0 5.9e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain DUF3301 PF11743.8 AAZ35186.1 - 0.0092 15.6 2.7 3.4 7.4 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF3301) DUF4381 PF14316.6 AAZ35186.1 - 0.13 12.5 5.5 0.1 12.8 0.9 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) Ly49 PF08391.10 AAZ35186.1 - 0.2 12.0 0.3 0.5 10.7 0.3 1.6 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region GspL_C PF12693.7 AAZ35186.1 - 1.7 8.5 10.8 0.77 9.6 1.7 3.2 3 0 0 3 3 3 0 GspL periplasmic domain S1_2 PF13509.6 AAZ35187.1 - 3.3e-30 103.9 0.2 1.3e-19 70.0 0.0 2.9 3 0 0 3 3 3 2 S1 domain CvfB_WH PF17783.1 AAZ35187.1 - 1.4e-22 79.2 0.1 2.4e-22 78.5 0.1 1.4 1 0 0 1 1 1 1 CvfB-like winged helix domain S1 PF00575.23 AAZ35187.1 - 0.011 16.1 0.0 3.1 8.2 0.0 3.8 1 1 2 3 3 3 0 S1 RNA binding domain CMAS PF02353.20 AAZ35188.1 - 3.7e-108 361.0 0.0 4.5e-108 360.7 0.0 1.0 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 AAZ35188.1 - 4.8e-16 59.2 0.1 9.8e-16 58.3 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAZ35188.1 - 1.4e-14 54.5 0.2 5.1e-14 52.7 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAZ35188.1 - 9.3e-12 45.0 0.0 1.8e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAZ35188.1 - 2.5e-10 40.4 0.0 4e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAZ35188.1 - 2.5e-09 37.8 0.0 4.7e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AAZ35188.1 - 4e-05 23.2 0.0 6.4e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 AAZ35188.1 - 0.0005 19.5 0.0 0.00071 19.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 AAZ35188.1 - 0.00079 19.4 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 AAZ35188.1 - 0.00093 18.2 0.0 0.0014 17.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_15 PF09445.10 AAZ35188.1 - 0.0039 16.8 0.0 0.0056 16.3 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Ubie_methyltran PF01209.18 AAZ35188.1 - 0.0042 16.5 0.0 0.011 15.1 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 AAZ35188.1 - 0.0051 16.6 0.0 0.0074 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.13 AAZ35188.1 - 0.0061 16.1 0.0 0.0097 15.4 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 MetW PF07021.12 AAZ35188.1 - 0.007 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 AAZ35188.1 - 0.0072 16.3 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 AAZ35188.1 - 0.0086 16.2 0.0 0.014 15.5 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase KaiB PF07689.12 AAZ35188.1 - 0.062 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 KaiB domain UPF0020 PF01170.18 AAZ35188.1 - 0.083 12.6 0.0 0.19 11.4 0.0 1.6 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Acyl-CoA_dh_2 PF08028.11 AAZ35189.1 - 3.6e-13 49.9 6.7 4.6e-13 49.6 5.4 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 AAZ35189.1 - 7.5e-08 32.5 0.1 1.6e-07 31.4 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 AAZ35189.1 - 2.7e-05 24.8 0.0 0.00011 22.8 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 AAZ35189.1 - 0.0098 16.1 0.8 0.018 15.3 0.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Glyco_hydro_3 PF00933.21 AAZ35190.1 - 3.9e-77 259.7 0.0 5.2e-77 259.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain FhuF PF06276.12 AAZ35191.1 - 6.8e-15 55.9 0.0 1.4e-14 54.8 0.0 1.5 1 1 0 1 1 1 1 Ferric iron reductase FhuF-like transporter FhuF_C PF11575.8 AAZ35191.1 - 2.2e-06 27.5 6.8 4.8e-06 26.4 6.8 1.6 1 0 0 1 1 1 1 FhuF 2Fe-2S C-terminal domain SARA PF11409.8 AAZ35191.1 - 0.048 13.9 0.9 0.11 12.8 0.9 1.5 1 0 0 1 1 1 0 Smad anchor for receptor activation (SARA) Hydrolase_like PF13242.6 AAZ35192.1 - 3.6e-11 42.9 0.1 8e-11 41.9 0.1 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like PNK3P PF08645.11 AAZ35192.1 - 5e-09 36.1 0.0 5.7e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase HAD_2 PF13419.6 AAZ35192.1 - 1.3e-07 31.9 0.0 0.00036 20.7 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAZ35192.1 - 2.3e-05 24.8 0.0 6.3e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AAZ35192.1 - 0.00056 20.0 0.0 0.0015 18.6 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 AAZ35192.1 - 0.0085 16.5 0.0 0.034 14.6 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Aldedh PF00171.22 AAZ35193.1 - 4.2e-87 292.6 0.0 5.2e-87 292.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Thymidylate_kin PF02223.17 AAZ35194.1 - 5.6e-48 163.1 0.0 6.3e-48 162.9 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 AAZ35194.1 - 7.6e-06 26.3 0.1 9.7e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AAZ35194.1 - 0.0014 19.0 0.0 0.0028 17.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 AAZ35194.1 - 0.0034 17.6 0.0 0.0057 16.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 AAZ35194.1 - 0.16 11.7 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase AAA_16 PF13191.6 AAZ35194.1 - 0.17 12.3 5.8 0.53 10.7 5.8 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 AAZ35194.1 - 0.19 12.3 0.0 0.34 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Peptidase_M16_C PF05193.21 AAZ35195.1 - 2.2e-34 119.0 0.0 3.1e-30 105.6 0.0 2.9 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 AAZ35195.1 - 6.9e-07 29.4 0.0 1.1e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) PT PF04886.12 AAZ35195.1 - 0.37 10.4 4.0 0.33 10.5 2.0 1.9 2 0 0 2 2 2 0 PT repeat Radical_SAM PF04055.21 AAZ35196.1 - 1.8e-13 51.2 0.0 2.9e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily LIAS_N PF16881.5 AAZ35196.1 - 4.6e-08 33.4 0.1 2.9e-07 30.9 0.1 2.0 2 0 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family UPF0149 PF03695.13 AAZ35197.1 - 7.2e-33 114.3 6.4 8.1e-33 114.1 6.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0149) NTP_transferase PF00483.23 AAZ35198.1 - 8.6e-71 238.4 0.0 1.1e-70 238.1 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AAZ35198.1 - 2.6e-11 44.1 0.0 2.8e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 AAZ35198.1 - 0.0039 16.9 0.0 0.0069 16.2 0.0 1.3 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase T6SS_HCP PF05638.12 AAZ35199.1 - 3.4e-36 124.5 0.0 4e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 Type VI secretion system effector, Hcp PseudoU_synth_2 PF00849.22 AAZ35200.1 - 5.1e-32 111.2 0.0 7.3e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 AAZ35200.1 - 1.5e-07 31.0 0.3 2.7e-07 30.2 0.3 1.4 1 0 0 1 1 1 1 S4 domain Ribonuclease_P PF00825.18 AAZ35201.1 - 8e-29 99.9 0.0 9.1e-29 99.8 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease P GvpL_GvpF PF06386.11 AAZ35202.1 - 0.12 12.2 0.0 0.13 12.2 0.0 1.0 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF AAA_2 PF07724.14 AAZ35203.1 - 7.5e-48 162.9 2.2 1.6e-39 135.8 0.3 2.5 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 AAZ35203.1 - 8.8e-17 61.8 0.2 1.8e-07 31.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AAZ35203.1 - 1.1e-07 32.0 0.0 2e-05 24.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 AAZ35203.1 - 2.6e-07 31.0 0.1 5.4e-05 23.5 0.0 2.8 3 0 0 3 3 2 1 AAA domain MCM PF00493.23 AAZ35203.1 - 1.2e-06 27.8 0.1 0.0002 20.6 0.0 2.2 2 0 0 2 2 2 1 MCM P-loop domain RuvB_N PF05496.12 AAZ35203.1 - 1.8e-05 24.5 0.8 0.057 13.2 0.1 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 AAZ35203.1 - 1.9e-05 25.1 3.3 0.00013 22.4 0.9 2.8 2 1 0 2 2 2 1 AAA ATPase domain ClpB_D2-small PF10431.9 AAZ35203.1 - 5.2e-05 23.2 1.0 0.00035 20.6 0.1 2.8 3 0 0 3 3 3 1 C-terminal, D2-small domain, of ClpB protein Mg_chelatase PF01078.21 AAZ35203.1 - 8e-05 22.1 0.7 0.0027 17.1 0.3 3.3 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 AAZ35203.1 - 0.00013 22.5 0.2 0.0017 18.9 0.0 2.7 3 0 0 3 3 3 1 AAA domain Sigma54_activat PF00158.26 AAZ35203.1 - 0.00076 19.2 0.0 0.011 15.5 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain TniB PF05621.11 AAZ35203.1 - 0.0028 17.1 0.1 0.013 14.9 0.0 2.2 2 0 0 2 2 2 1 Bacterial TniB protein AAA_28 PF13521.6 AAZ35203.1 - 0.0047 17.2 0.0 0.03 14.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 AAZ35203.1 - 0.0089 16.2 0.0 0.021 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 AAZ35203.1 - 0.014 15.1 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 AAZ35203.1 - 0.015 15.3 0.0 4.8 7.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 AAZ35203.1 - 0.02 14.9 0.0 0.27 11.2 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 AAZ35203.1 - 0.021 14.0 0.0 0.045 12.9 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain NTPase_1 PF03266.15 AAZ35203.1 - 0.03 14.2 0.2 1.9 8.3 0.0 2.3 2 0 0 2 2 2 0 NTPase DEAD PF00270.29 AAZ35203.1 - 0.053 13.3 0.3 1.4 8.7 0.0 2.5 3 0 0 3 3 3 0 DEAD/DEAH box helicase RNA_helicase PF00910.22 AAZ35203.1 - 0.055 13.9 0.0 1.3 9.5 0.0 2.2 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 AAZ35203.1 - 0.057 12.9 0.1 0.14 11.7 0.0 1.6 2 0 0 2 2 1 0 P-loop containing dynein motor region SRP54 PF00448.22 AAZ35203.1 - 0.064 12.9 0.1 0.16 11.6 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 AAZ35203.1 - 0.068 12.9 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 AAZ35203.1 - 0.07 13.0 0.1 2.3 8.1 0.0 2.9 3 1 0 3 3 3 0 NACHT domain ABC_tran PF00005.27 AAZ35203.1 - 0.08 13.4 0.0 0.22 12.0 0.0 1.8 1 1 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 AAZ35203.1 - 0.086 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase ResIII PF04851.15 AAZ35203.1 - 0.15 12.1 0.0 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 AAZ35203.1 - 0.38 11.1 2.5 3 8.2 2.5 2.5 1 1 0 1 1 1 0 AAA domain BPD_transp_1 PF00528.22 AAZ35204.1 - 6.7e-20 71.6 8.0 6.7e-20 71.6 8.0 2.1 2 1 1 3 3 3 1 Binding-protein-dependent transport system inner membrane component Sigma70_r4_2 PF08281.12 AAZ35205.1 - 9.2e-16 57.3 0.1 1.3e-14 53.6 0.0 2.4 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 AAZ35205.1 - 3.9e-15 55.4 0.5 5.9e-15 54.8 0.5 1.3 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_ECF PF07638.11 AAZ35205.1 - 9.8e-07 28.8 0.0 1.4e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 ECF sigma factor Sigma70_r4 PF04545.16 AAZ35205.1 - 9.5e-06 25.0 0.1 3.4e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_24 PF13412.6 AAZ35205.1 - 0.00018 21.0 0.0 0.00041 19.9 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 AAZ35205.1 - 0.00019 21.1 1.7 0.0005 19.8 0.0 2.5 2 2 1 3 3 3 1 Homeodomain-like domain GerE PF00196.19 AAZ35205.1 - 0.00022 20.7 0.0 0.0004 19.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_7 PF02796.15 AAZ35205.1 - 0.005 16.9 0.0 0.085 12.9 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_5 PF01022.20 AAZ35205.1 - 0.0055 16.5 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_10 PF04967.12 AAZ35205.1 - 0.0094 15.7 0.1 0.02 14.7 0.1 1.5 1 0 0 1 1 1 1 HTH DNA binding domain HTH_20 PF12840.7 AAZ35205.1 - 0.012 15.7 0.2 0.042 13.9 0.1 2.0 2 1 0 2 2 2 0 Helix-turn-helix domain MarR_2 PF12802.7 AAZ35205.1 - 0.012 15.5 0.3 0.051 13.5 0.0 2.1 3 0 0 3 3 2 0 MarR family HTH_40 PF14493.6 AAZ35205.1 - 0.02 15.3 0.0 0.048 14.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain TnsD PF15978.5 AAZ35205.1 - 0.023 13.7 0.0 0.04 12.9 0.0 1.4 1 0 0 1 1 1 0 Tn7-like transposition protein D HTH_11 PF08279.12 AAZ35205.1 - 0.031 14.2 0.0 0.089 12.8 0.0 1.7 2 0 0 2 2 1 0 HTH domain HTH_Crp_2 PF13545.6 AAZ35205.1 - 0.036 14.0 0.0 0.087 12.8 0.0 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Trp_repressor PF01371.19 AAZ35205.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Trp repressor protein HTH_IclR PF09339.10 AAZ35205.1 - 0.12 12.2 0.3 0.51 10.2 0.0 2.2 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_36 PF13730.6 AAZ35205.1 - 0.17 11.8 0.1 0.5 10.3 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_IclR PF09339.10 AAZ35206.1 - 1.7e-16 59.7 2.5 3.1e-16 58.9 0.3 2.5 2 1 1 3 3 3 1 IclR helix-turn-helix domain IclR PF01614.18 AAZ35206.1 - 1.7e-13 50.5 0.0 2.4e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_24 PF13412.6 AAZ35206.1 - 7.9e-07 28.5 0.0 2.8e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 AAZ35206.1 - 6.9e-06 25.9 1.1 3.1e-05 23.8 0.1 2.3 2 0 0 2 2 2 1 MarR family HTH_5 PF01022.20 AAZ35206.1 - 8e-05 22.4 0.0 0.00034 20.4 0.0 2.1 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family MarR PF01047.22 AAZ35206.1 - 0.0002 21.2 0.0 0.00049 20.0 0.0 1.7 1 0 0 1 1 1 1 MarR family TrmB PF01978.19 AAZ35206.1 - 0.00022 21.1 0.1 0.0006 19.7 0.0 1.7 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.6 AAZ35206.1 - 0.0018 18.2 0.1 0.004 17.1 0.1 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_27 PF13463.6 AAZ35206.1 - 0.0076 16.7 0.2 4.7 7.8 0.1 2.4 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_AsnC-type PF13404.6 AAZ35206.1 - 0.015 15.1 0.8 0.1 12.5 0.1 2.7 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain HTH_29 PF13551.6 AAZ35206.1 - 0.016 15.2 0.1 0.041 13.9 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn helix HTH_45 PF14947.6 AAZ35206.1 - 0.02 14.8 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix HTH_20 PF12840.7 AAZ35206.1 - 0.04 14.0 0.6 0.11 12.5 0.2 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.6 AAZ35206.1 - 0.045 13.6 0.0 0.21 11.5 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain HTH_1 PF00126.27 AAZ35206.1 - 0.1 12.6 0.0 1.4 8.9 0.0 2.7 3 0 0 3 3 3 0 Bacterial regulatory helix-turn-helix protein, lysR family Rrf2 PF02082.20 AAZ35206.1 - 0.14 12.5 0.0 0.46 10.9 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator DUF2829 PF11195.8 AAZ35207.1 - 0.076 13.3 0.1 36 4.7 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2829) TetR_C_3 PF08362.11 AAZ35208.1 - 5.8e-60 201.4 0.0 7.4e-60 201.0 0.0 1.1 1 0 0 1 1 1 1 YcdC-like protein, C-terminal region TetR_N PF00440.23 AAZ35208.1 - 6.2e-17 61.1 0.1 1.1e-16 60.3 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_29 PF17938.1 AAZ35208.1 - 0.0047 17.0 0.0 0.0065 16.6 0.0 1.3 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain Sigma54_CBD PF04963.13 AAZ35208.1 - 0.037 13.9 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain TetR_C_9 PF14514.6 AAZ35208.1 - 0.12 12.5 0.0 0.25 11.4 0.0 1.6 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Epimerase_2 PF02350.19 AAZ35209.1 - 1.9e-113 378.9 0.0 2.2e-113 378.6 0.0 1.0 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase ACP_syn_III_C PF08541.10 AAZ35209.1 - 0.15 12.2 0.0 4.7 7.5 0.0 3.0 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal AMP-binding PF00501.28 AAZ35210.1 - 2.7e-149 497.4 0.0 6.9e-82 275.3 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 AAZ35210.1 - 8.4e-51 173.1 0.0 1.2e-50 172.5 0.0 1.2 1 0 0 1 1 1 1 Condensation domain ketoacyl-synt PF00109.26 AAZ35210.1 - 2.8e-45 154.9 0.3 6.4e-45 153.7 0.3 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 AAZ35210.1 - 1.2e-35 123.1 0.0 3.4e-35 121.6 0.0 1.9 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 AAZ35210.1 - 4.5e-35 120.2 1.6 4.5e-35 120.2 1.6 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 AAZ35210.1 - 9.2e-28 96.4 4.3 2e-11 44.0 0.1 4.3 4 0 0 4 4 4 3 Phosphopantetheine attachment site AMP-binding_C PF13193.6 AAZ35210.1 - 5.6e-19 68.9 0.0 7.7e-13 49.2 0.0 2.7 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Thioesterase PF00975.20 AAZ35210.1 - 1.6e-17 64.4 0.2 3.4e-17 63.3 0.2 1.6 1 0 0 1 1 1 1 Thioesterase domain KAsynt_C_assoc PF16197.5 AAZ35210.1 - 3.2e-16 59.8 0.0 1.1e-15 58.1 0.0 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 AAZ35210.1 - 2.1e-13 50.2 0.0 4.4e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 AAZ35210.1 - 2.3e-07 30.5 0.0 2.3e-06 27.3 0.0 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 AAZ35210.1 - 7.3e-07 29.0 0.0 1.6e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 AAZ35210.1 - 0.00013 21.5 0.0 0.00024 20.5 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain NAD_binding_10 PF13460.6 AAZ35210.1 - 0.00042 20.3 0.0 0.0012 18.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 AAZ35210.1 - 0.0053 15.9 0.0 0.01 15.0 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 AAZ35210.1 - 0.11 11.9 0.0 0.33 10.3 0.0 1.8 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 AAZ35210.1 - 0.15 11.1 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 AAZ35210.1 - 0.18 10.9 0.0 0.93 8.6 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein SirB PF04247.12 AAZ35211.1 - 1.3 9.1 7.9 0.2 11.7 1.6 2.1 2 0 0 2 2 2 0 Invasion gene expression up-regulator, SirB NAD_binding_2 PF03446.15 AAZ35212.1 - 8.4e-40 136.5 4.4 1.4e-39 135.8 4.4 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 AAZ35212.1 - 4.1e-38 130.3 1.0 7.3e-38 129.5 1.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 AAZ35212.1 - 3.5e-06 26.5 0.9 6.1e-06 25.7 0.1 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 AAZ35212.1 - 5e-06 26.5 0.8 1.2e-05 25.3 0.8 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 AAZ35212.1 - 9e-06 26.2 0.3 9e-06 26.2 0.3 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.9 AAZ35212.1 - 0.00011 22.0 5.0 0.0013 18.6 0.5 2.3 2 0 0 2 2 2 1 Rossmann-like domain UDPG_MGDP_dh_N PF03721.14 AAZ35212.1 - 0.0006 19.4 0.4 0.0023 17.6 0.1 1.9 1 1 1 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain IlvN PF07991.12 AAZ35212.1 - 0.034 13.7 0.1 0.078 12.6 0.1 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 AAZ35212.1 - 0.038 14.2 0.0 0.14 12.5 0.0 1.9 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.16 AAZ35212.1 - 0.054 13.1 0.2 0.13 11.9 0.2 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 AAZ35212.1 - 0.078 13.0 0.4 0.37 10.9 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DpaA_N PF16924.5 AAZ35212.1 - 0.16 12.1 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Dipicolinate synthase subunit A N-terminal domain HlyD_D23 PF16576.5 AAZ35213.1 - 4.2e-14 52.3 4.1 3.1e-13 49.4 4.1 2.1 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 AAZ35213.1 - 3.4e-13 49.2 4.0 2.4e-11 43.2 0.4 3.6 4 0 0 4 4 4 2 Biotin-lipoyl like HlyD_3 PF13437.6 AAZ35213.1 - 7.9e-07 29.7 10.0 1.6e-05 25.5 0.2 3.5 3 2 0 3 3 3 2 HlyD family secretion protein HlyD PF00529.20 AAZ35213.1 - 0.0019 18.0 16.3 0.01 15.7 16.3 2.4 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS DUF4061 PF13270.6 AAZ35213.1 - 0.13 12.6 0.2 0.72 10.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) Ribosomal_L13 PF00572.18 AAZ35214.1 - 3.7e-58 195.2 0.0 4.2e-58 195.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 Acyl-CoA_dh_2 PF08028.11 AAZ35215.1 - 6.1e-18 65.4 5.9 6.1e-18 65.4 5.9 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_1 PF00441.24 AAZ35215.1 - 1.9e-09 37.9 2.9 3.3e-09 37.1 2.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Response_reg PF00072.24 AAZ35216.1 - 1.2e-16 60.9 0.7 2.3e-16 60.0 0.7 1.4 1 1 0 1 1 1 1 Response regulator receiver domain FleQ PF06490.11 AAZ35216.1 - 0.0075 16.6 0.0 0.0094 16.3 0.0 1.1 1 0 0 1 1 1 1 Flagellar regulatory protein FleQ Ribosomal_L31 PF01197.18 AAZ35217.1 - 2.6e-28 98.0 0.0 3e-28 97.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L31 AsmA PF05170.14 AAZ35218.1 - 8.7e-123 411.3 0.1 1e-122 411.0 0.1 1.0 1 0 0 1 1 1 1 AsmA family AsmA_2 PF13502.6 AAZ35218.1 - 2.8e-24 85.9 9.5 5.7e-23 81.7 1.1 3.3 3 2 0 3 3 3 2 AsmA-like C-terminal region DUF748 PF05359.11 AAZ35218.1 - 0.0044 17.2 8.2 0.091 12.9 0.8 4.2 3 1 1 4 4 4 2 Domain of Unknown Function (DUF748) LptC PF06835.13 AAZ35219.1 - 2.3e-54 183.6 0.3 2.6e-54 183.4 0.3 1.0 1 0 0 1 1 1 1 Lipopolysaccharide-assembly, LptC-related OstA PF03968.14 AAZ35219.1 - 0.01 16.0 0.6 0.078 13.2 0.1 2.0 1 1 1 2 2 2 0 OstA-like protein NAGLU_N PF12971.7 AAZ35219.1 - 0.04 13.7 0.0 0.07 12.9 0.0 1.5 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain CompInhib_SCIN PF11546.8 AAZ35219.1 - 0.15 12.1 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 Staphylococcal complement inhibitor SCIN Thioredoxin_2 PF13098.6 AAZ35220.1 - 2.1e-26 92.5 0.0 3.1e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain DsbC_N PF10411.9 AAZ35220.1 - 1.7e-16 59.4 0.0 2.9e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Disulfide bond isomerase protein N-terminus DSBA PF01323.20 AAZ35220.1 - 3.8e-09 36.6 0.1 0.00026 20.8 0.0 2.3 1 1 0 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 AAZ35220.1 - 1.8e-08 34.7 0.1 0.00034 20.8 0.1 2.2 1 1 1 2 2 2 2 Thioredoxin Thioredoxin_3 PF13192.6 AAZ35220.1 - 0.0017 18.4 0.1 1.6 8.8 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin domain Glutaredoxin PF00462.24 AAZ35220.1 - 0.0027 17.9 0.3 0.033 14.4 0.1 2.5 3 0 0 3 3 3 1 Glutaredoxin CT_A_B PF02626.15 AAZ35220.1 - 0.017 14.8 0.0 0.03 13.9 0.0 1.4 2 0 0 2 2 2 0 Carboxyltransferase domain, subdomain A and B LYTB PF02401.18 AAZ35220.1 - 0.053 12.8 0.0 0.075 12.3 0.0 1.2 1 0 0 1 1 1 0 LytB protein TraF PF13728.6 AAZ35220.1 - 0.14 11.9 0.0 1.6 8.5 0.0 2.1 2 0 0 2 2 2 0 F plasmid transfer operon protein FxsA PF04186.13 AAZ35221.1 - 5.9e-34 116.5 11.7 9.4e-34 115.8 11.7 1.2 1 0 0 1 1 1 1 FxsA cytoplasmic membrane protein DUF5325 PF17259.2 AAZ35221.1 - 1.8 8.5 7.8 0.42 10.5 4.6 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5325) MFS_1 PF07690.16 AAZ35222.1 - 2.4e-44 151.7 53.1 3.7e-43 147.8 46.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 AAZ35222.1 - 0.61 9.3 37.6 52 3.0 37.6 2.1 1 1 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB Bac_GDH PF05088.12 AAZ35223.1 - 0 2180.6 0.0 0 2180.4 0.0 1.0 1 0 0 1 1 1 1 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog PF00208.21 AAZ35223.1 - 0.0011 18.7 0.4 0.0037 17.0 0.0 1.9 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase HTH_31 PF13560.6 AAZ35223.1 - 0.022 15.1 0.3 13 6.2 0.0 4.2 3 0 0 3 3 3 0 Helix-turn-helix domain His_Phos_1 PF00300.22 AAZ35224.1 - 7.8e-22 77.9 0.0 1.2e-10 41.4 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) ABM PF03992.16 AAZ35225.1 - 0.049 13.8 0.1 0.071 13.2 0.1 1.2 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase Thioredoxin PF00085.20 AAZ35226.1 - 3.3e-35 120.2 0.0 3.7e-35 120.0 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 AAZ35226.1 - 1.3e-07 32.0 0.0 1.7e-06 28.4 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 AAZ35226.1 - 1e-06 28.9 0.0 1.9e-05 24.9 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.6 AAZ35226.1 - 0.00019 21.2 0.0 0.00021 21.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 AAZ35226.1 - 0.0013 18.6 0.0 0.0016 18.3 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 AAZ35226.1 - 0.0016 18.4 0.0 0.0027 17.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_7 PF13899.6 AAZ35226.1 - 0.002 18.3 0.0 0.0028 17.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 AAZ35226.1 - 0.0044 16.4 0.0 0.0051 16.2 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 AAZ35226.1 - 0.11 12.4 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family Redoxin PF08534.10 AAZ35226.1 - 0.14 11.9 0.0 0.87 9.3 0.0 1.9 1 1 1 2 2 2 0 Redoxin HipA_C PF07804.12 AAZ35227.1 - 7.2e-16 58.5 0.0 1.1e-15 58.0 0.0 1.3 1 1 0 1 1 1 1 HipA-like C-terminal domain DUF2252 PF10009.9 AAZ35227.1 - 0.18 10.8 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) HrpB_C PF08482.10 AAZ35228.1 - 9.4e-55 184.6 0.6 1.5e-54 184.0 0.6 1.3 1 0 0 1 1 1 1 ATP-dependent helicase C-terminal SBP_bac_3 PF00497.20 AAZ35229.1 - 1.7e-17 63.6 0.0 2.3e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Sugar_tr PF00083.24 AAZ35230.1 - 1.7e-31 109.6 33.1 1.1e-21 77.3 10.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 AAZ35230.1 - 7.4e-30 104.1 78.4 2.7e-24 85.8 50.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DNase-RNase PF02577.14 AAZ35230.1 - 0.18 11.5 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Bifunctional nuclease PhoU PF01895.19 AAZ35231.1 - 9.5e-43 144.6 11.3 2.6e-23 82.3 3.2 2.2 2 0 0 2 2 2 2 PhoU domain ING PF12998.7 AAZ35231.1 - 0.0015 19.1 1.5 0.0087 16.6 0.3 2.4 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding DUF1759 PF03564.15 AAZ35231.1 - 0.028 14.4 1.0 0.27 11.2 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1759) Apolipoprotein PF01442.18 AAZ35231.1 - 0.048 13.5 4.2 0.12 12.3 0.9 2.1 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF1664 PF07889.12 AAZ35231.1 - 0.088 12.8 2.3 1.2 9.2 0.4 3.1 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) Aminotran_5 PF00266.19 AAZ35232.1 - 4.2e-77 259.6 0.8 5.1e-77 259.3 0.8 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 AAZ35232.1 - 4.6e-05 22.9 0.2 6.1e-05 22.4 0.2 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 AAZ35232.1 - 0.0001 21.8 1.3 0.00016 21.1 1.3 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 AAZ35232.1 - 0.021 13.4 0.0 0.028 12.9 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Claudin_2 PF13903.6 AAZ35233.1 - 0.73 9.6 4.9 0.34 10.6 2.9 1.4 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction TssN PF17555.2 AAZ35233.1 - 1.2 8.5 6.2 1.2 8.5 6.2 1.0 1 0 0 1 1 1 0 Type VI secretion system, TssN DUF2530 PF10745.9 AAZ35233.1 - 7.5 6.9 8.2 0.97 9.7 2.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) GCV_H PF01597.19 AAZ35234.1 - 1.1e-32 112.5 0.0 1.2e-32 112.3 0.0 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein TonB_C PF03544.14 AAZ35235.1 - 8.9e-07 29.3 0.0 1.7e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Gram-negative bacterial TonB protein C-terminal TonB_2 PF13103.6 AAZ35235.1 - 0.0086 16.3 0.0 0.043 14.1 0.0 2.3 1 0 0 1 1 1 1 TonB C terminal Metal_hydrol PF10118.9 AAZ35236.1 - 0.11 12.2 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Predicted metal-dependent hydrolase FXR_C1 PF16096.5 AAZ35236.1 - 0.24 11.6 3.1 0.38 11.0 3.1 1.3 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 AMP-binding PF00501.28 AAZ35237.1 - 1.3e-71 241.4 0.0 2.3e-71 240.6 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 AAZ35237.1 - 4.2e-56 190.0 0.0 9.4e-56 188.8 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein PP-binding PF00550.25 AAZ35237.1 - 6.6e-14 52.0 0.4 1.8e-13 50.6 0.2 1.9 2 0 0 2 2 2 1 Phosphopantetheine attachment site Epimerase PF01370.21 AAZ35237.1 - 1.5e-10 41.0 0.0 2.6e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 AAZ35237.1 - 5.8e-06 26.3 0.0 1.3e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 KR domain AMP-binding_C PF13193.6 AAZ35237.1 - 0.00015 22.7 0.0 0.00039 21.3 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.19 AAZ35237.1 - 0.00025 20.1 0.0 0.00038 19.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 AAZ35237.1 - 0.0011 18.5 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 AAZ35237.1 - 0.02 14.3 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Polysacc_synt_2 PF02719.15 AAZ35237.1 - 0.041 13.0 0.0 0.066 12.3 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PEPCK_ATP PF01293.20 AAZ35238.1 - 4.2e-189 629.1 0.0 4.8e-189 628.9 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_24 PF13479.6 AAZ35238.1 - 0.012 15.3 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 AAZ35238.1 - 0.019 15.3 0.0 0.033 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 AAZ35238.1 - 0.077 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AAZ35238.1 - 0.14 12.3 0.1 0.32 11.1 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AAZ35238.1 - 0.23 11.3 1.2 0.55 10.0 0.1 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain Lyase_1 PF00206.20 AAZ35240.1 - 2.6e-97 326.0 0.0 3.2e-97 325.7 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 AAZ35240.1 - 1.9e-20 73.0 0.0 4.5e-20 71.8 0.0 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus BPD_transp_1 PF00528.22 AAZ35242.1 - 2.2e-15 56.9 17.2 2.2e-15 56.9 17.2 2.2 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component GST_N_2 PF13409.6 AAZ35243.1 - 6.8e-11 42.3 0.0 1.2e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 AAZ35243.1 - 2e-09 37.7 0.0 3.6e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 AAZ35243.1 - 1e-08 35.0 0.3 2.4e-08 33.8 0.3 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 AAZ35243.1 - 4.7e-06 26.9 0.0 1.3e-05 25.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 AAZ35243.1 - 0.0014 18.8 0.0 0.0025 18.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 AAZ35243.1 - 0.079 13.2 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain CsgG PF03783.14 AAZ35244.1 - 7.4e-29 100.5 0.7 9.4e-29 100.2 0.7 1.1 1 0 0 1 1 1 1 Curli production assembly/transport component CsgG TolB_N PF04052.13 AAZ35244.1 - 1.3e-05 25.3 0.0 2.5e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 TolB amino-terminal domain LpoB PF13036.6 AAZ35244.1 - 0.00088 19.2 0.6 0.025 14.5 0.6 2.8 1 1 0 1 1 1 1 Peptidoglycan-synthase activator LpoB MacB_PCD PF12704.7 AAZ35245.1 - 6.9e-16 59.2 1.1 6.9e-16 59.2 1.1 1.9 2 0 0 2 2 2 1 MacB-like periplasmic core domain FtsX PF02687.21 AAZ35245.1 - 1.6e-14 54.2 17.0 8.8e-13 48.5 5.5 3.2 3 0 0 3 3 3 2 FtsX-like permease family HAD_2 PF13419.6 AAZ35246.1 - 5.1e-34 117.9 0.0 6e-34 117.7 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAZ35246.1 - 8.1e-21 75.3 0.0 4.1e-18 66.4 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AAZ35246.1 - 1.8e-06 27.9 0.0 3.4e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like NIF PF03031.18 AAZ35246.1 - 8.3e-06 25.6 0.0 0.0011 18.8 0.0 2.2 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase_6 PF13344.6 AAZ35246.1 - 0.0085 16.2 0.1 3.2 7.9 0.0 2.8 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase TetR_C_2 PF08361.11 AAZ35246.1 - 0.073 13.2 0.1 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 MAATS-type transcriptional repressor, C-terminal region Response_reg PF00072.24 AAZ35248.1 - 1.5e-16 60.6 0.0 2.1e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Peptidase_M20 PF01546.28 AAZ35249.1 - 0.017 14.9 0.0 0.019 14.7 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Myb_DNA-bind_6 PF13921.6 AAZ35249.1 - 0.074 13.3 0.0 0.088 13.1 0.0 1.1 1 0 0 1 1 1 0 Myb-like DNA-binding domain MCPsignal PF00015.21 AAZ35250.1 - 1.5e-42 145.3 23.3 1.5e-42 145.3 23.3 5.6 2 2 3 5 5 5 1 Methyl-accepting chemotaxis protein (MCP) signalling domain PilJ PF13675.6 AAZ35250.1 - 1.7e-24 86.1 0.5 1.7e-24 86.1 0.5 6.0 3 2 4 7 7 7 2 Type IV pili methyl-accepting chemotaxis transducer N-term ATG16 PF08614.11 AAZ35250.1 - 0.019 15.2 1.3 0.019 15.2 1.3 4.5 5 1 0 5 5 5 0 Autophagy protein 16 (ATG16) Sh_2 PF17512.2 AAZ35250.1 - 0.045 13.5 2.0 0.17 11.7 2.0 2.0 1 0 0 1 1 1 0 Metapneumovirus Small hydrophobic protein BLOC1_2 PF10046.9 AAZ35250.1 - 0.14 12.5 0.2 0.14 12.5 0.2 6.0 4 1 2 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 EphA2_TM PF14575.6 AAZ35250.1 - 0.16 12.9 0.1 4.3 8.3 0.0 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Neur_chan_memb PF02932.16 AAZ35250.1 - 0.51 10.4 3.0 0.82 9.7 0.4 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region OppC_N PF12911.7 AAZ35250.1 - 0.82 9.7 2.8 26 4.9 1.2 2.4 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C TssO PF17561.2 AAZ35250.1 - 4.8 7.3 6.4 29 4.7 0.1 4.3 4 1 1 5 5 5 0 Type VI secretion system, TssO AAA PF00004.29 AAZ35250.1 - 9.1 6.7 8.6 2.8 8.4 0.3 3.6 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) Phage_integrase PF00589.22 AAZ35252.1 - 0.014 15.1 0.1 0.035 13.9 0.1 1.6 2 0 0 2 2 2 0 Phage integrase family GIT_SHD PF08518.11 AAZ35252.1 - 0.082 12.5 1.1 0.21 11.3 1.1 1.7 1 0 0 1 1 1 0 Spa2 homology domain (SHD) of GIT Peptidase_A6 PF01829.16 AAZ35252.1 - 0.16 11.3 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase A6 family DUF469 PF04320.14 AAZ35253.1 - 2.4e-36 124.6 0.1 2.8e-36 124.4 0.1 1.0 1 0 0 1 1 1 1 Protein with unknown function (DUF469) BON PF04972.17 AAZ35254.1 - 2.2e-50 168.8 12.5 2.7e-18 66.0 1.7 3.1 3 0 0 3 3 3 3 BON domain TbpB_B_D PF01298.18 AAZ35254.1 - 0.17 12.3 0.6 2.2 8.7 0.2 2.5 2 1 0 2 2 2 0 C-lobe and N-lobe beta barrels of Tf-binding protein B HMA PF00403.26 AAZ35254.1 - 2.5 8.6 5.0 17 5.9 0.2 3.4 3 0 0 3 3 3 0 Heavy-metal-associated domain Acetyltransf_3 PF13302.7 AAZ35255.1 - 2.4e-20 73.6 0.0 2.9e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain HIN PF02760.15 AAZ35255.1 - 0.089 12.5 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 HIN-200/IF120x domain 2OG-FeII_Oxy_2 PF13532.6 AAZ35256.1 - 4e-50 170.7 0.0 4.9e-50 170.4 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 AAZ35256.1 - 0.02 15.7 0.0 0.031 15.2 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Yop-YscD_cpl PF16697.5 AAZ35257.1 - 5.5e-19 68.3 0.0 1.4e-18 66.9 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Yop-YscD_ppl PF16693.5 AAZ35257.1 - 0.004 16.6 0.1 0.0054 16.2 0.1 1.1 1 0 0 1 1 1 1 Inner membrane component of T3SS, periplasmic domain FHA PF00498.26 AAZ35257.1 - 0.026 14.9 0.0 0.095 13.1 0.0 1.9 2 0 0 2 2 2 0 FHA domain GST_N_3 PF13417.6 AAZ35258.1 - 3.5e-12 46.6 0.0 6.5e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AAZ35258.1 - 4.9e-09 36.4 0.0 7.7e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 AAZ35258.1 - 1.9e-07 31.3 0.0 3.5e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 AAZ35258.1 - 1.5e-05 24.9 0.4 3.1e-05 23.9 0.4 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_4 PF14834.6 AAZ35258.1 - 0.002 18.5 0.2 0.003 17.9 0.2 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 AAZ35258.1 - 0.003 18.3 0.0 0.0055 17.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 AAZ35258.1 - 0.026 14.8 0.0 0.043 14.1 0.0 1.4 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein Microvir_H PF04687.12 AAZ35258.1 - 0.079 12.3 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Microvirus H protein (pilot protein) CoA_trans PF01144.23 AAZ35259.1 - 4.4e-49 166.8 0.0 5.1e-49 166.6 0.0 1.0 1 0 0 1 1 1 1 Coenzyme A transferase Gln-synt_C PF00120.24 AAZ35260.1 - 1.6e-110 369.4 0.0 1.8e-110 369.2 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 AAZ35260.1 - 0.00016 21.4 0.0 0.00033 20.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Glyco_transf_5 PF08323.11 AAZ35260.1 - 0.15 11.7 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Starch synthase catalytic domain polyprenyl_synt PF00348.17 AAZ35261.1 - 4.6e-73 245.4 0.0 5.4e-73 245.2 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase SQS_PSY PF00494.19 AAZ35261.1 - 0.00072 19.1 0.3 0.0012 18.4 0.3 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase HEPPP_synt_1 PF07307.11 AAZ35261.1 - 0.18 11.4 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 ADH_N PF08240.12 AAZ35262.1 - 6.6e-26 90.3 3.4 1.2e-25 89.5 3.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AAZ35262.1 - 1.2e-22 80.3 0.0 2.1e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AAZ35262.1 - 1.1e-05 26.5 0.0 1.9e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 AAZ35262.1 - 3e-05 23.4 0.0 4.9e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 AAZ35262.1 - 5.6e-05 22.5 0.1 9.6e-05 21.8 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 AAZ35262.1 - 0.00058 20.1 0.2 0.001 19.3 0.2 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Oxidored_nitro PF00148.19 AAZ35262.1 - 0.064 12.0 0.0 0.097 11.4 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase 3HCDH_N PF02737.18 AAZ35262.1 - 0.092 12.6 0.1 0.14 12.0 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NADH_4Fe-4S PF10589.9 AAZ35262.1 - 0.12 12.4 5.0 0.3 11.2 5.0 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region DUF1161 PF06649.12 AAZ35263.1 - 1e-22 80.1 1.2 1.3e-22 79.7 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1161) DUF4030 PF13222.6 AAZ35263.1 - 0.026 14.7 0.0 0.03 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4030) Acetyltransf_1 PF00583.25 AAZ35264.1 - 3.6e-08 33.6 0.1 5.9e-08 33.0 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAZ35264.1 - 5.7e-07 29.9 0.0 1.2e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAZ35264.1 - 0.00078 19.4 0.1 0.0027 17.6 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 AAZ35264.1 - 0.004 17.1 0.0 0.011 15.7 0.0 1.7 2 0 0 2 2 2 1 ESCO1/2 acetyl-transferase Acetyltransf_9 PF13527.7 AAZ35264.1 - 0.015 15.3 1.7 0.02 14.9 0.1 2.0 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AAZ35264.1 - 0.043 14.5 0.0 0.084 13.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-dskA_traR PF01258.17 AAZ35265.1 - 8.8e-12 44.8 0.0 1.6e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic dksA/traR C4-type zinc finger Sigma70_r1_1 PF03979.14 AAZ35265.1 - 0.32 11.1 2.3 0.18 11.9 0.5 1.5 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 TRAP-delta PF05404.12 AAZ35266.1 - 0.062 12.8 0.0 0.068 12.7 0.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein, delta subunit precursor (TRAP-delta) EAL PF00563.20 AAZ35267.1 - 4.5e-72 242.4 0.1 9.9e-72 241.3 0.1 1.6 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AAZ35267.1 - 2.4e-27 95.7 0.4 8.6e-27 93.9 0.1 2.1 3 0 0 3 3 3 1 Diguanylate cyclase, GGDEF domain dCache_3 PF14827.6 AAZ35267.1 - 2.4e-15 56.8 0.2 4.9e-15 55.8 0.2 1.5 1 0 0 1 1 1 1 Double sensory domain of two-component sensor kinase HAMP PF00672.25 AAZ35267.1 - 2.5e-13 50.2 0.1 9.1e-13 48.4 0.1 2.1 1 0 0 1 1 1 1 HAMP domain DJ-1_PfpI PF01965.24 AAZ35267.1 - 0.067 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family DUF4388 PF14332.6 AAZ35267.1 - 0.071 13.4 0.1 0.56 10.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4388) PCuAC PF04314.13 AAZ35268.1 - 9.3e-35 118.7 1.1 1.2e-34 118.3 1.1 1.1 1 0 0 1 1 1 1 Copper chaperone PCu(A)C DUF824 PF05688.11 AAZ35268.1 - 0.00047 19.9 0.2 0.0011 18.7 0.2 1.7 1 0 0 1 1 1 1 Salmonella repeat of unknown function (DUF824) adh_short PF00106.25 AAZ35269.1 - 8.5e-55 185.2 4.2 9.9e-55 185.0 4.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAZ35269.1 - 1e-53 182.3 3.1 1.4e-53 181.9 3.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAZ35269.1 - 6.6e-18 65.3 4.0 1.9e-17 63.7 4.0 1.7 1 1 0 1 1 1 1 KR domain Pyr_redox_2 PF07992.14 AAZ35270.1 - 1.2e-69 234.8 4.8 1.2e-69 234.8 4.8 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 AAZ35270.1 - 9e-41 138.6 1.4 1.6e-40 137.8 0.7 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 AAZ35270.1 - 1.1e-18 67.6 5.0 9.3e-16 58.2 0.5 3.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAZ35270.1 - 3.4e-12 46.2 1.0 1e-07 31.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AAZ35270.1 - 2.8e-09 36.6 9.2 1.4e-08 34.2 0.4 3.6 4 0 0 4 4 4 1 FAD binding domain GIDA PF01134.22 AAZ35270.1 - 9.1e-08 31.6 6.7 1e-06 28.1 2.0 2.5 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 AAZ35270.1 - 9.9e-08 31.6 2.2 0.0012 18.2 0.1 2.6 2 1 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 AAZ35270.1 - 7.9e-07 28.8 1.9 1.1e-06 28.3 0.7 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 AAZ35270.1 - 1.8e-06 26.9 9.0 1.7e-05 23.7 0.4 3.6 3 1 1 4 4 4 1 HI0933-like protein AlaDh_PNT_C PF01262.21 AAZ35270.1 - 8.7e-06 25.2 4.6 0.012 15.0 0.4 2.7 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 AAZ35270.1 - 2.9e-05 24.2 2.1 0.12 12.6 0.1 2.9 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 AAZ35270.1 - 6.7e-05 22.9 2.9 0.00058 19.8 0.3 2.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 AAZ35270.1 - 0.00025 20.4 4.0 0.00039 19.7 0.1 2.8 2 1 1 3 3 3 1 Thi4 family 2-Hacid_dh_C PF02826.19 AAZ35270.1 - 0.0015 17.9 0.6 0.077 12.3 0.0 2.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Amino_oxidase PF01593.24 AAZ35270.1 - 0.0022 17.3 1.1 0.32 10.2 0.1 2.4 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.24 AAZ35270.1 - 0.0024 17.5 14.7 2.2 7.8 0.1 4.4 3 1 1 4 4 4 2 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 AAZ35270.1 - 0.022 14.3 1.7 0.39 10.2 0.1 2.4 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Lycopene_cycl PF05834.12 AAZ35270.1 - 0.057 12.5 2.9 0.64 9.0 0.2 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein Big_6 PF17936.1 AAZ35270.1 - 0.15 12.3 1.3 5 7.5 0.1 2.8 2 1 0 2 2 2 0 Bacterial Ig domain LEA_2 PF03168.13 AAZ35271.1 - 1.4e-22 80.1 0.1 1.9e-22 79.7 0.1 1.2 1 0 0 1 1 1 1 Late embryogenesis abundant protein PBP_like_2 PF12849.7 AAZ35272.1 - 6e-62 209.9 10.6 7.8e-62 209.5 10.6 1.0 1 0 0 1 1 1 1 PBP superfamily domain PBP_like PF12727.7 AAZ35272.1 - 2.8e-09 36.4 0.1 1.7e-08 33.8 0.1 2.1 2 1 0 2 2 2 1 PBP superfamily domain MFS_1 PF07690.16 AAZ35273.1 - 9e-42 143.2 49.4 1.7e-33 116.0 31.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AAZ35273.1 - 1.1e-26 93.7 27.7 8.9e-16 57.8 12.4 2.3 1 1 1 2 2 2 2 Sugar (and other) transporter OATP PF03137.20 AAZ35273.1 - 0.00038 18.9 0.4 0.00038 18.9 0.4 3.0 1 1 2 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 AAZ35273.1 - 0.0031 16.4 13.5 0.019 13.8 3.5 3.8 2 1 0 3 3 3 2 MFS_1 like family DUF4212 PF13937.6 AAZ35273.1 - 0.082 13.3 0.1 0.082 13.3 0.1 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4212) DUF1275 PF06912.11 AAZ35273.1 - 0.79 9.6 27.6 0.011 15.6 8.1 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1275) BPD_transp_1 PF00528.22 AAZ35274.1 - 3.5e-34 118.1 10.0 3.5e-34 118.1 10.0 1.7 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Herpes_pp85 PF04637.12 AAZ35274.1 - 0.069 11.6 0.0 0.095 11.1 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Abhydrolase_1 PF00561.20 AAZ35275.1 - 3.9e-24 85.7 0.5 3.5e-15 56.4 0.3 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AAZ35275.1 - 3.8e-16 59.1 0.1 5e-16 58.7 0.1 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AAZ35275.1 - 6.3e-15 56.4 9.0 8.5e-15 55.9 9.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 AAZ35275.1 - 2.1e-05 24.6 0.0 4.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein FSH1 PF03959.13 AAZ35275.1 - 0.0028 17.3 0.0 0.0041 16.8 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.7 AAZ35275.1 - 0.0068 16.2 0.0 0.25 11.1 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.20 AAZ35275.1 - 0.033 14.3 0.0 0.057 13.5 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Ser_hydrolase PF06821.13 AAZ35275.1 - 0.035 14.0 0.0 0.067 13.0 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase Ndr PF03096.14 AAZ35275.1 - 0.12 11.0 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 Ndr family SGL PF08450.12 AAZ35276.1 - 2.7e-62 210.5 0.1 3.3e-62 210.3 0.1 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 AAZ35276.1 - 2e-06 27.8 0.0 0.0023 18.0 0.0 2.7 2 1 1 3 3 3 2 Strictosidine synthase Reg_prop PF07494.11 AAZ35276.1 - 6.8e-05 22.6 1.6 3.2 8.3 0.0 4.7 5 0 0 5 5 5 1 Two component regulator propeller Arylesterase PF01731.20 AAZ35276.1 - 0.00011 22.3 0.0 0.057 13.6 0.0 2.6 2 0 0 2 2 2 2 Arylesterase DUF839 PF05787.13 AAZ35276.1 - 0.00011 21.5 0.1 0.0053 16.0 0.0 2.5 2 1 0 2 2 2 1 Bacterial protein of unknown function (DUF839) Lactonase PF10282.9 AAZ35276.1 - 0.012 14.9 0.0 0.51 9.5 0.0 2.2 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller TAT_signal PF10518.9 AAZ35276.1 - 0.12 12.3 0.3 0.2 11.6 0.3 1.4 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence FHIPEP PF00771.20 AAZ35277.1 - 9.6e-203 675.3 1.3 1.1e-202 675.1 1.3 1.0 1 0 0 1 1 1 1 FHIPEP family DUF2304 PF10066.9 AAZ35277.1 - 0.15 12.3 7.5 1.4 9.2 3.8 2.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) DUF5313 PF17240.2 AAZ35277.1 - 0.92 10.0 3.6 8.9 6.8 3.7 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5313) Trigger_N PF05697.13 AAZ35278.1 - 5.1e-40 137.1 0.4 5.1e-40 137.1 0.4 3.9 3 1 1 4 4 4 1 Bacterial trigger factor protein (TF) Trigger_C PF05698.14 AAZ35278.1 - 1.4e-38 132.4 15.0 1.5e-36 125.9 10.0 2.4 2 0 0 2 2 2 2 Bacterial trigger factor protein (TF) C-terminus FKBP_C PF00254.28 AAZ35278.1 - 9.2e-15 54.7 0.1 2.7e-14 53.3 0.1 1.8 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase SurA_N_3 PF13624.6 AAZ35278.1 - 0.00088 19.1 3.2 0.00088 19.1 3.2 2.7 2 1 0 2 2 2 1 SurA N-terminal domain Med15_fungi PF05397.12 AAZ35278.1 - 0.24 11.7 0.2 0.24 11.7 0.2 1.9 2 0 0 2 2 2 0 Mediator complex subunit 15 Vps39_2 PF10367.9 AAZ35278.1 - 3.1 8.3 4.7 1.5 9.3 0.6 2.4 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 SurA_N_2 PF13623.6 AAZ35278.1 - 5.4 6.9 11.9 0.18 11.7 0.6 3.3 2 1 2 4 4 4 0 SurA N-terminal domain RVT_1 PF00078.27 AAZ35279.1 - 1.6e-18 67.0 0.0 7.8e-18 64.8 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) GIIM PF08388.11 AAZ35279.1 - 0.025 14.6 0.0 0.069 13.2 0.0 1.7 1 0 0 1 1 1 0 Group II intron, maturase-specific domain Chor_lyase PF04345.13 AAZ35280.1 - 1.3e-49 168.1 0.0 1.7e-49 167.7 0.0 1.0 1 0 0 1 1 1 1 Chorismate lyase DUF98 PF01947.16 AAZ35280.1 - 0.012 15.6 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 0 p-hydroxybenzoic acid synthase PepSY_TM PF03929.16 AAZ35281.1 - 1.6e-62 211.8 7.1 2e-62 211.5 5.5 1.9 2 0 0 2 2 2 1 PepSY-associated TM region Flavodoxin_1 PF00258.25 AAZ35281.1 - 5.6e-26 91.5 0.0 1.1e-25 90.6 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 AAZ35281.1 - 3.9e-11 43.6 0.0 6.6e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_1 PF00667.20 AAZ35281.1 - 2.6e-05 23.9 0.0 0.002 17.7 0.0 2.1 1 1 1 2 2 2 1 FAD binding domain PepSY_TM_like_2 PF16357.5 AAZ35281.1 - 0.00026 21.0 0.6 0.061 13.3 0.0 3.0 2 1 0 2 2 2 1 Putative PepSY_TM-like DUF2627 PF11118.8 AAZ35281.1 - 0.15 12.7 1.9 0.17 12.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) SBP_bac_3 PF00497.20 AAZ35282.1 - 7.1e-43 146.6 0.0 9.9e-43 146.2 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Adeno_shaft PF00608.17 AAZ35282.1 - 0.0043 16.8 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Adenoviral fibre protein (repeat/shaft region) Phosphonate-bd PF12974.7 AAZ35282.1 - 0.006 16.2 0.0 0.12 11.9 0.0 2.4 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_11 PF13531.6 AAZ35282.1 - 0.01 15.6 0.1 0.074 12.8 0.2 2.2 2 1 0 2 2 2 0 Bacterial extracellular solute-binding protein Lig_chan-Glu_bd PF10613.9 AAZ35282.1 - 0.026 14.7 0.0 0.049 13.8 0.0 1.6 1 1 0 1 1 1 0 Ligated ion channel L-glutamate- and glycine-binding site AAA_31 PF13614.6 AAZ35283.1 - 5.1e-63 212.2 0.0 8.6e-63 211.4 0.0 1.3 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 AAZ35283.1 - 1.4e-26 93.1 0.0 1.9e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 AAZ35283.1 - 5e-13 48.9 0.1 1.2e-11 44.4 0.1 2.1 1 1 0 1 1 1 1 ATPase MipZ CBP_BcsQ PF06564.12 AAZ35283.1 - 1.8e-12 47.2 0.0 1.3e-11 44.4 0.0 2.0 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ParA PF10609.9 AAZ35283.1 - 5.6e-10 39.1 0.3 3.3e-09 36.5 0.3 2.0 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 AAZ35283.1 - 1.6e-07 31.1 0.0 2.2e-05 24.1 0.0 2.1 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 AAZ35283.1 - 1.8e-06 27.4 0.2 1.7e-05 24.2 0.2 2.1 1 1 0 1 1 1 1 Anion-transporting ATPase VirC1 PF07015.11 AAZ35283.1 - 7.7e-05 22.1 0.2 0.00061 19.2 0.0 2.0 2 0 0 2 2 2 1 VirC1 protein CLP1_P PF16575.5 AAZ35283.1 - 0.00051 19.9 0.1 0.0011 18.7 0.0 1.6 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop ATP_bind_1 PF03029.17 AAZ35283.1 - 0.0013 18.5 0.1 0.03 14.1 0.1 2.1 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein SRP54 PF00448.22 AAZ35283.1 - 0.0055 16.3 0.1 0.022 14.4 0.1 1.9 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_25 PF13481.6 AAZ35283.1 - 0.075 12.6 0.0 0.47 10.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 AAZ35283.1 - 0.11 11.4 0.0 0.21 10.5 0.0 1.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DHO_dh PF01180.21 AAZ35284.1 - 9.1e-86 287.7 0.0 1.2e-85 287.3 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.15 AAZ35284.1 - 1.8e-06 27.6 4.4 4.5e-06 26.3 4.5 1.5 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 AAZ35284.1 - 0.008 15.2 0.4 0.018 14.1 0.4 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 AAZ35284.1 - 0.083 11.9 0.7 0.14 11.1 0.2 1.5 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Peptidase_M75 PF09375.10 AAZ35285.1 - 1.3e-43 149.5 0.1 1.6e-43 149.3 0.1 1.0 1 0 0 1 1 1 1 Imelysin TSP_NTD PF17804.1 AAZ35285.1 - 0.1 12.8 1.0 1.1 9.5 0.1 2.2 2 0 0 2 2 2 0 Tail specific protease N-terminal domain BLI1 PF17324.2 AAZ35285.1 - 0.15 12.7 0.4 12 6.6 0.0 2.6 3 0 0 3 3 3 0 BLOC-1 interactor 1 Peptidase_S24 PF00717.23 AAZ35286.1 - 8.7e-22 76.9 0.2 1.8e-21 75.9 0.2 1.5 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 AAZ35286.1 - 1.5e-06 28.1 0.0 0.013 15.3 0.0 2.3 2 0 0 2 2 2 2 Signal peptidase, peptidase S26 DUF4096 PF13340.6 AAZ35287.1 - 5.7e-25 87.3 0.4 1.5e-24 86.0 0.4 1.8 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1 PF01609.21 AAZ35287.1 - 1.3e-13 51.1 0.0 2.3e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AAZ35287.1 - 7e-10 39.2 0.2 2.1e-09 37.6 0.2 1.9 1 0 0 1 1 1 1 Transposase DDE domain HTH_Tnp_Tc3_2 PF01498.18 AAZ35287.1 - 0.061 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Transposase Amidase_3 PF01520.18 AAZ35288.1 - 1.6e-46 158.6 0.0 2e-46 158.3 0.0 1.1 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase AMIN PF11741.8 AAZ35288.1 - 2.2e-18 66.2 0.0 4e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 AMIN domain DEAD_assoc PF08494.11 AAZ35288.1 - 0.063 13.1 0.1 0.49 10.2 0.0 2.1 2 0 0 2 2 2 0 DEAD/H associated DUF4096 PF13340.6 AAZ35289.1 - 5.8e-25 87.3 0.4 1.5e-24 86.0 0.4 1.8 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1 PF01609.21 AAZ35289.1 - 3.2e-14 53.1 0.0 5.7e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AAZ35289.1 - 7.2e-10 39.1 0.2 2.1e-09 37.6 0.2 1.9 1 0 0 1 1 1 1 Transposase DDE domain HTH_Tnp_Tc3_2 PF01498.18 AAZ35289.1 - 0.061 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Transposase Ribosomal_L10 PF00466.20 AAZ35290.1 - 5.4e-25 87.4 0.2 7.9e-25 86.9 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 MotA_ExbB PF01618.16 AAZ35291.1 - 1.1e-39 135.1 0.2 2.1e-39 134.2 0.2 1.5 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family FAD-oxidase_C PF02913.19 AAZ35292.1 - 2.4e-55 187.9 0.0 3.7e-55 187.3 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 AAZ35292.1 - 1.7e-34 118.5 0.4 3.4e-34 117.5 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain Fer4_8 PF13183.6 AAZ35292.1 - 9.4e-13 48.4 1.6 2.3e-12 47.1 1.6 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_20 PF14691.6 AAZ35292.1 - 0.032 14.0 0.2 0.068 12.9 0.2 1.5 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster BBE PF08031.12 AAZ35292.1 - 0.039 14.1 0.0 0.086 13.0 0.0 1.5 1 0 0 1 1 1 0 Berberine and berberine like Fer4_17 PF13534.6 AAZ35292.1 - 0.058 14.0 4.2 0.53 10.9 4.2 2.3 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 AAZ35292.1 - 0.12 13.0 2.4 0.35 11.5 2.4 1.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAZ35292.1 - 2 8.6 6.0 1.9 8.6 2.6 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 AAZ35292.1 - 5.5 7.7 6.6 2.7 8.7 2.3 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain K_oxygenase PF13434.6 AAZ35293.1 - 3.1e-18 66.0 0.0 1.2e-16 60.9 0.0 2.7 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 AAZ35293.1 - 8.7e-18 64.6 0.0 8.5e-14 51.5 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 AAZ35293.1 - 3.9e-14 52.9 0.8 5.2e-11 42.8 0.1 2.9 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 AAZ35293.1 - 3.9e-14 52.6 0.0 3.8e-12 46.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AAZ35293.1 - 3.7e-12 46.5 1.9 2.2e-05 24.2 0.4 3.8 3 1 1 4 4 4 3 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AAZ35293.1 - 3.7e-07 30.3 1.5 2.5e-05 24.4 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 AAZ35293.1 - 4.5e-07 30.3 1.0 0.034 14.7 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AAZ35293.1 - 2.3e-06 27.1 0.2 2.5e-05 23.7 0.1 2.2 3 0 0 3 3 3 1 FAD binding domain FAD_binding_2 PF00890.24 AAZ35293.1 - 1.5e-05 24.2 6.4 0.00059 19.0 0.1 3.1 4 0 0 4 4 4 2 FAD binding domain AlaDh_PNT_C PF01262.21 AAZ35293.1 - 2.3e-05 23.8 0.9 0.024 13.9 0.0 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 AAZ35293.1 - 2.4e-05 23.2 3.9 0.13 10.9 1.3 3.8 4 0 0 4 4 4 2 HI0933-like protein Lycopene_cycl PF05834.12 AAZ35293.1 - 0.00098 18.3 0.4 0.00098 18.3 0.4 2.1 3 0 0 3 3 3 1 Lycopene cyclase protein Amino_oxidase PF01593.24 AAZ35293.1 - 0.009 15.3 0.1 1.7 7.8 0.0 2.5 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase GIDA PF01134.22 AAZ35293.1 - 0.014 14.5 3.8 0.15 11.1 0.3 2.8 3 0 0 3 3 3 0 Glucose inhibited division protein A NAD_binding_7 PF13241.6 AAZ35293.1 - 0.078 13.4 0.3 0.47 10.9 0.1 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding IlvN PF07991.12 AAZ35293.1 - 0.11 12.1 0.0 2.5 7.7 0.0 2.5 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain FMO-like PF00743.19 AAZ35293.1 - 0.18 10.2 0.0 1.5 7.1 0.0 2.2 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like Thi4 PF01946.17 AAZ35293.1 - 0.42 9.8 2.3 0.43 9.8 0.2 1.9 2 0 0 2 2 2 0 Thi4 family Trp_halogenase PF04820.14 AAZ35293.1 - 2.5 6.8 4.2 26 3.5 0.3 2.7 3 0 0 3 3 3 0 Tryptophan halogenase Rieske PF00355.26 AAZ35294.1 - 5.9e-18 64.6 0.1 1.1e-17 63.7 0.1 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain PaO PF08417.12 AAZ35294.1 - 0.0012 18.9 0.0 0.0023 18.1 0.0 1.5 1 0 0 1 1 1 1 Pheophorbide a oxygenase Ring_hydroxyl_A PF00848.19 AAZ35294.1 - 0.0061 16.5 0.2 0.62 10.0 0.0 2.4 2 0 0 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) GntR PF00392.21 AAZ35295.1 - 1.2e-21 76.1 2.5 8.5e-13 47.8 0.2 2.9 3 0 0 3 3 3 2 Bacterial regulatory proteins, gntR family FCD PF07729.12 AAZ35295.1 - 1e-10 42.1 8.6 1e-10 42.1 8.6 1.8 2 0 0 2 2 2 1 FCD domain HTH_Crp_2 PF13545.6 AAZ35295.1 - 1.2e-08 34.8 0.0 0.0024 17.8 0.0 3.2 3 0 0 3 3 3 2 Crp-like helix-turn-helix domain Rrf2 PF02082.20 AAZ35295.1 - 1.2e-05 25.5 0.1 0.14 12.6 0.0 3.3 3 1 0 3 3 3 2 Transcriptional regulator HTH_DeoR PF08220.12 AAZ35295.1 - 1.6e-05 24.6 0.0 0.013 15.2 0.0 2.6 2 0 0 2 2 2 2 DeoR-like helix-turn-helix domain TrmB PF01978.19 AAZ35295.1 - 2.4e-05 24.1 0.3 0.018 14.9 0.1 3.5 3 1 1 4 4 4 1 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.12 AAZ35295.1 - 0.00027 20.8 0.0 0.79 9.7 0.0 3.3 3 0 0 3 3 3 2 HTH domain MarR_2 PF12802.7 AAZ35295.1 - 0.00046 20.0 3.6 0.43 10.5 0.1 3.9 3 0 0 3 3 3 1 MarR family Fe_dep_repress PF01325.19 AAZ35295.1 - 0.003 17.7 0.0 0.095 12.9 0.0 2.6 2 0 0 2 2 2 1 Iron dependent repressor, N-terminal DNA binding domain FaeA PF04703.12 AAZ35295.1 - 0.0081 16.5 0.0 0.88 10.0 0.0 2.5 2 0 0 2 2 2 1 FaeA-like protein HTH_24 PF13412.6 AAZ35295.1 - 0.012 15.1 0.0 3.4 7.3 0.0 2.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding PaaX PF07848.12 AAZ35295.1 - 0.014 15.6 0.1 0.74 10.1 0.0 2.5 2 0 0 2 2 2 0 PaaX-like protein TFIIE_alpha PF02002.17 AAZ35295.1 - 0.02 14.7 0.0 3.6 7.5 0.0 2.7 2 0 0 2 2 2 0 TFIIE alpha subunit HTH_28 PF13518.6 AAZ35295.1 - 0.022 14.9 0.3 3.6 7.8 0.1 2.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_29 PF13551.6 AAZ35295.1 - 0.035 14.1 0.0 11 6.1 0.0 2.6 2 0 0 2 2 2 0 Winged helix-turn helix HTH_5 PF01022.20 AAZ35295.1 - 0.13 12.2 0.9 3.6 7.5 0.0 3.1 4 0 0 4 4 4 0 Bacterial regulatory protein, arsR family RepL PF05732.11 AAZ35295.1 - 0.14 11.6 0.0 0.57 9.6 0.0 1.9 2 0 0 2 2 2 0 Firmicute plasmid replication protein (RepL) Transposase_mut PF00872.18 AAZ35295.1 - 0.14 11.0 0.1 0.21 10.4 0.1 1.2 1 0 0 1 1 1 0 Transposase, Mutator family HTH_36 PF13730.6 AAZ35295.1 - 0.15 12.0 0.0 16 5.6 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain MS_channel PF00924.18 AAZ35296.1 - 8.8e-15 54.8 1.4 8.8e-15 54.8 1.4 1.7 2 0 0 2 2 2 1 Mechanosensitive ion channel PUA PF01472.20 AAZ35296.1 - 0.026 14.5 0.0 0.17 11.9 0.1 2.0 2 0 0 2 2 2 0 PUA domain TM_helix PF05552.12 AAZ35296.1 - 1.3 9.1 6.7 7.7 6.6 0.4 2.9 2 1 0 2 2 2 0 Conserved TM helix Ham1p_like PF01725.16 AAZ35297.1 - 3.1e-59 200.0 0.0 3.5e-59 199.9 0.0 1.0 1 0 0 1 1 1 1 Ham1 family SBP_bac_3 PF00497.20 AAZ35298.1 - 2.1e-30 105.9 0.0 2.6e-24 85.9 0.0 2.2 2 0 0 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 PAS PF00989.25 AAZ35298.1 - 2.1e-08 34.2 0.0 3.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AAZ35298.1 - 1.8e-06 28.2 0.0 7.6e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 AAZ35298.1 - 0.0068 16.7 0.0 0.48 10.7 0.0 2.6 2 0 0 2 2 2 1 PAS fold PAS_10 PF13596.6 AAZ35298.1 - 0.049 14.2 0.1 0.15 12.7 0.0 1.8 2 0 0 2 2 2 0 PAS domain MadL PF03817.13 AAZ35299.1 - 1.8e-48 163.4 16.3 2.1e-48 163.2 16.3 1.0 1 0 0 1 1 1 1 Malonate transporter MadL subunit Peripla_BP_5 PF13433.6 AAZ35300.1 - 4.1e-176 585.3 0.1 4.7e-176 585.1 0.1 1.0 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_6 PF13458.6 AAZ35300.1 - 9.4e-72 242.5 1.4 1.1e-71 242.3 1.4 1.0 1 0 0 1 1 1 1 Periplasmic binding protein CdiI_N PF18228.1 AAZ35300.1 - 0.16 11.9 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 CdiI N-terminal domain MCPsignal PF00015.21 AAZ35301.1 - 4.5e-42 143.8 24.6 4.5e-42 143.8 24.6 3.1 2 1 1 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain 4HB_MCP_1 PF12729.7 AAZ35301.1 - 7.9e-22 77.7 0.0 7.9e-22 77.7 0.0 3.5 2 1 0 4 4 4 1 Four helix bundle sensory module for signal transduction HAMP PF00672.25 AAZ35301.1 - 7.1e-07 29.5 14.7 9.4e-07 29.1 0.4 4.9 6 1 0 6 6 6 2 HAMP domain DUF948 PF06103.11 AAZ35301.1 - 5 7.5 29.5 1.4 9.3 1.2 5.2 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF948) Peptidase_C1 PF00112.23 AAZ35302.1 - 9.6e-17 61.8 0.0 1.7e-16 61.0 0.0 1.3 1 1 0 1 1 1 1 Papain family cysteine protease Peptidase_C39_2 PF13529.6 AAZ35302.1 - 0.00088 19.8 0.0 0.0018 18.8 0.0 1.4 1 1 0 1 1 1 1 Peptidase_C39 like family Response_reg PF00072.24 AAZ35303.1 - 1.5e-27 96.0 0.3 1.6e-27 95.9 0.3 1.0 1 0 0 1 1 1 1 Response regulator receiver domain B12-binding PF02310.19 AAZ35303.1 - 0.00042 20.4 0.0 0.00056 20.0 0.0 1.1 1 0 0 1 1 1 1 B12 binding domain FleQ PF06490.11 AAZ35303.1 - 0.034 14.5 0.0 0.039 14.3 0.0 1.1 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ She2p PF11435.8 AAZ35303.1 - 0.19 11.4 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 RNA binding protein She2p FliS PF02561.14 AAZ35304.1 - 6.1e-32 110.3 0.0 6.8e-32 110.1 0.0 1.0 1 0 0 1 1 1 1 Flagellar protein FliS HTH_18 PF12833.7 AAZ35305.1 - 2.7e-21 75.6 0.6 6.6e-21 74.4 0.6 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAZ35305.1 - 3.4e-16 58.9 0.5 1.5e-07 31.3 0.2 2.6 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family DJ-1_PfpI PF01965.24 AAZ35305.1 - 7.2e-07 29.2 0.0 9.5e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DiS_P_DiS PF06750.13 AAZ35307.1 - 3.6e-35 119.9 0.9 7.7e-35 118.9 0.2 1.8 2 0 0 2 2 2 1 Bacterial Peptidase A24 N-terminal domain Peptidase_A24 PF01478.18 AAZ35307.1 - 2.4e-25 89.0 15.3 2.4e-25 89.0 15.3 2.0 2 0 0 2 2 2 1 Type IV leader peptidase family zf-ribbon_3 PF13248.6 AAZ35307.1 - 0.42 10.1 4.3 4.5 6.8 0.4 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf_UBZ PF18439.1 AAZ35307.1 - 1.2 8.8 3.5 12 5.6 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Nudix_N_2 PF14803.6 AAZ35307.1 - 2.1 8.4 4.7 17 5.4 1.0 2.3 2 0 0 2 2 2 0 Nudix N-terminal Dus PF01207.17 AAZ35308.1 - 9e-110 366.6 0.0 1.1e-109 366.3 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) SOR_SNZ PF01680.17 AAZ35308.1 - 0.00023 21.0 0.9 0.0077 16.0 0.2 2.2 1 1 1 2 2 2 1 SOR/SNZ family His_biosynth PF00977.21 AAZ35308.1 - 0.00047 19.7 0.4 0.0027 17.2 0.5 1.7 1 1 0 1 1 1 1 Histidine biosynthesis protein NanE PF04131.14 AAZ35308.1 - 0.0032 16.7 0.4 0.014 14.6 0.1 2.0 1 1 1 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase MR_MLE_C PF13378.6 AAZ35308.1 - 0.022 14.3 0.2 0.079 12.5 0.0 2.0 2 0 0 2 2 2 0 Enolase C-terminal domain-like DHO_dh PF01180.21 AAZ35308.1 - 0.023 13.9 0.0 0.26 10.5 0.0 2.1 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase DeoC PF01791.9 AAZ35308.1 - 0.025 14.2 0.8 0.13 11.9 0.8 2.0 1 1 0 1 1 1 0 DeoC/LacD family aldolase PEP_mutase PF13714.6 AAZ35308.1 - 0.054 13.0 0.5 0.16 11.4 0.5 1.7 1 1 1 2 2 2 0 Phosphoenolpyruvate phosphomutase Pterin_bind PF00809.22 AAZ35308.1 - 0.086 12.5 0.4 0.2 11.3 0.1 1.8 2 0 0 2 2 2 0 Pterin binding enzyme PEP_hydrolase PF09370.10 AAZ35308.1 - 0.093 11.9 1.0 2.6 7.2 0.3 2.2 2 0 0 2 2 2 0 Phosphoenolpyruvate hydrolase-like Sod_Fe_C PF02777.18 AAZ35309.1 - 1.5e-40 137.5 0.0 1.3e-39 134.5 0.0 2.1 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 AAZ35309.1 - 1.2e-34 118.6 1.0 1.9e-34 118.0 1.0 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain FlgN PF05130.12 AAZ35310.1 - 3.5e-28 98.9 10.0 3.9e-28 98.8 10.0 1.0 1 0 0 1 1 1 1 FlgN protein Transposase_mut PF00872.18 AAZ35311.1 - 5.4e-116 387.6 0.0 6.7e-116 387.3 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ35311.1 - 7.7e-05 23.0 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain DUF4844 PF16133.5 AAZ35311.1 - 0.23 12.0 0.0 0.55 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) TP_methylase PF00590.20 AAZ35312.1 - 6.7e-32 111.2 0.2 1.4e-31 110.1 0.2 1.6 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases CbiG_N PF11760.8 AAZ35312.1 - 3.5e-24 84.6 1.1 1.1e-23 83.1 0.1 2.2 2 0 0 2 2 2 1 Cobalamin synthesis G N-terminal CbiG_C PF01890.16 AAZ35312.1 - 0.1 13.1 0.1 0.22 12.1 0.1 1.5 1 0 0 1 1 1 0 Cobalamin synthesis G C-terminus MarR_2 PF12802.7 AAZ35313.1 - 8.5e-10 38.4 1.1 1.9e-09 37.3 0.2 2.1 2 1 0 2 2 2 1 MarR family MarR PF01047.22 AAZ35313.1 - 1.9e-09 37.3 0.1 3.5e-09 36.5 0.1 1.4 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 AAZ35313.1 - 1.2e-06 28.9 0.3 2e-06 28.2 0.0 1.5 2 0 0 2 2 2 1 Winged helix DNA-binding domain HxlR PF01638.17 AAZ35313.1 - 0.0002 21.1 0.0 0.00032 20.5 0.0 1.2 1 0 0 1 1 1 1 HxlR-like helix-turn-helix HTH_Crp_2 PF13545.6 AAZ35313.1 - 0.009 16.0 0.2 0.017 15.1 0.2 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain PadR PF03551.14 AAZ35313.1 - 0.04 13.9 0.0 0.065 13.2 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family GntR PF00392.21 AAZ35313.1 - 0.04 13.6 0.1 0.04 13.6 0.1 1.9 3 0 0 3 3 3 0 Bacterial regulatory proteins, gntR family OEP PF02321.18 AAZ35314.1 - 8.9e-58 195.2 32.4 1.6e-32 112.9 6.8 2.0 2 0 0 2 2 2 2 Outer membrane efflux protein POT1PC PF16686.5 AAZ35314.1 - 0.097 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 ssDNA-binding domain of telomere protection protein DICT PF10069.9 AAZ35314.1 - 0.13 12.1 3.2 0.42 10.4 0.2 2.5 2 1 0 2 2 2 0 Sensory domain in DIguanylate Cyclases and Two-component system Sec8_exocyst PF04048.14 AAZ35314.1 - 0.4 10.5 5.6 0.21 11.5 0.3 2.5 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain Methyltrans_SAM PF10672.9 AAZ35315.1 - 2.8e-31 108.8 0.1 6.2e-23 81.4 0.1 2.1 2 0 0 2 2 2 2 S-adenosylmethionine-dependent methyltransferase Cons_hypoth95 PF03602.15 AAZ35315.1 - 0.00011 21.9 0.2 0.0075 15.9 0.2 2.2 1 1 0 1 1 1 1 Conserved hypothetical protein 95 HATPase_c_4 PF13749.6 AAZ35316.1 - 2.9e-20 72.2 0.0 5.8e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 Putative ATP-dependent DNA helicase recG C-terminal AlbA_2 PF04326.14 AAZ35316.1 - 1.5e-16 60.8 0.0 2.4e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Putative DNA-binding domain DUF2600 PF10776.9 AAZ35316.1 - 0.13 11.1 0.0 0.45 9.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2600) Glyco_transf_5 PF08323.11 AAZ35317.1 - 2e-70 237.3 0.0 3.8e-70 236.4 0.0 1.4 2 0 0 2 2 2 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 AAZ35317.1 - 1.3e-17 63.9 0.0 2e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 AAZ35317.1 - 5.2e-10 40.0 0.1 1.1e-09 38.9 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 AAZ35317.1 - 5.5e-10 39.8 0.0 1.1e-09 38.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAZ35317.1 - 2.6e-06 27.6 0.4 3.1e-05 24.0 0.4 2.7 1 1 0 1 1 1 1 Glycosyltransferase Family 4 TspO_MBR PF03073.15 AAZ35318.1 - 2.3e-35 121.6 27.7 2.8e-35 121.3 27.7 1.0 1 0 0 1 1 1 1 TspO/MBR family SmpA_OmlA PF04355.13 AAZ35319.1 - 2.6e-17 62.4 0.2 3.5e-17 61.9 0.2 1.2 1 0 0 1 1 1 1 SmpA / OmlA family BLIP PF07467.11 AAZ35319.1 - 8.6e-05 23.1 0.0 0.00014 22.5 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase inhibitor (BLIP) DUF3558 PF12079.8 AAZ35319.1 - 0.076 13.0 0.7 0.22 11.5 0.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3558) NADHdh PF00146.21 AAZ35320.1 - 5.1e-118 393.7 20.1 6e-118 393.5 20.1 1.0 1 0 0 1 1 1 1 NADH dehydrogenase DUF2976 PF11190.8 AAZ35320.1 - 0.092 12.6 0.2 0.092 12.6 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) Ribosomal_L35p PF01632.19 AAZ35321.1 - 9.8e-25 86.8 8.5 1.1e-24 86.7 8.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L35 MFS_1 PF07690.16 AAZ35322.1 - 8.6e-39 133.4 54.4 8.6e-39 133.4 54.4 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily tRNA-synt_1g PF09334.11 AAZ35323.1 - 1.1e-63 215.3 0.0 1.4e-63 215.0 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 AAZ35323.1 - 2.7e-07 30.2 0.0 0.021 14.2 0.0 2.5 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1 PF00133.22 AAZ35323.1 - 0.00043 18.7 0.0 0.0011 17.3 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 AAZ35323.1 - 0.054 12.4 0.0 0.1 11.5 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (K) RHH_5 PF07878.11 AAZ35323.1 - 0.16 11.9 0.1 1.1 9.2 0.0 2.4 3 0 0 3 3 3 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 PolC_DP2 PF03833.13 AAZ35323.1 - 0.38 8.5 1.1 0.52 8.1 1.1 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DOPA_dioxygen PF08883.11 AAZ35324.1 - 3.3e-32 110.8 0.1 3.7e-32 110.7 0.1 1.0 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family LAL_C2 PF18603.1 AAZ35324.1 - 0.041 14.0 0.0 0.28 11.4 0.0 2.0 2 0 0 2 2 2 0 L-amino acid ligase C-terminal domain 2 Aldose_epim PF01263.20 AAZ35325.1 - 3.3e-46 158.0 0.0 3.8e-46 157.8 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase MBD PF01429.19 AAZ35325.1 - 0.12 12.1 0.2 2.9 7.7 0.1 2.3 1 1 1 2 2 2 0 Methyl-CpG binding domain Glyco_hydro_25 PF01183.20 AAZ35326.1 - 1.4e-33 116.5 0.2 1.7e-33 116.3 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 BPD_transp_1 PF00528.22 AAZ35327.1 - 4.9e-23 81.8 7.7 4.9e-23 81.8 7.7 1.3 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component Isochorismatase PF00857.20 AAZ35328.1 - 1.6e-39 135.9 0.0 2.1e-39 135.5 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family Ketoacyl-synt_C PF02801.22 AAZ35329.1 - 2e-25 89.1 0.0 8.7e-25 87.0 0.1 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 AAZ35329.1 - 8.7e-23 81.2 0.1 1.8e-22 80.2 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.23 AAZ35329.1 - 0.0003 20.3 0.0 0.00058 19.3 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain ExbD PF02472.16 AAZ35330.1 - 6.7e-30 103.9 1.4 8.1e-30 103.7 1.4 1.0 1 0 0 1 1 1 1 Biopolymer transport protein ExbD/TolR DUF2149 PF09919.9 AAZ35330.1 - 0.18 12.1 1.6 0.24 11.6 1.6 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) EAL PF00563.20 AAZ35331.1 - 1.5e-73 247.3 0.0 2.8e-73 246.4 0.0 1.5 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AAZ35331.1 - 9.6e-50 168.5 0.9 2.8e-49 167.0 0.1 2.1 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain MHYT PF03707.16 AAZ35331.1 - 1.5e-27 95.5 25.6 2.9e-13 49.8 2.4 4.6 4 0 0 4 4 4 3 Bacterial signalling protein N terminal repeat AMP-binding PF00501.28 AAZ35332.1 - 8.1e-87 291.5 0.0 1.1e-86 291.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAZ35332.1 - 1.5e-25 90.0 0.0 3.2e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 AAZ35332.1 - 1.3e-22 79.4 0.4 2.8e-22 78.4 0.4 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus DUF3828 PF12883.7 AAZ35332.1 - 0.17 12.2 0.1 0.38 11.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3828) Ribosomal_S20p PF01649.18 AAZ35333.1 - 7.6e-28 97.0 10.6 8.6e-28 96.8 10.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S20 SPK PF04435.18 AAZ35333.1 - 0.0081 16.5 0.1 0.0093 16.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF545) 5-FTHF_cyc-lig PF01812.20 AAZ35334.1 - 2.4e-40 138.4 0.0 2.7e-40 138.2 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family TetR_C_11 PF16859.5 AAZ35334.1 - 0.22 11.9 7.0 1.5 9.1 5.1 2.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Lipoprotein_16 PF03923.13 AAZ35335.1 - 9.6e-12 44.8 0.0 1.2e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized lipoprotein T2SSM_b PF10741.9 AAZ35335.1 - 0.088 12.6 0.1 4.8 7.0 0.1 2.7 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b CobD_Cbib PF03186.13 AAZ35336.1 - 6.9e-96 320.7 1.1 9.5e-96 320.2 1.1 1.2 1 0 0 1 1 1 1 CobD/Cbib protein AmpE PF17113.5 AAZ35336.1 - 3.7e-07 29.8 2.2 5.9e-07 29.1 2.2 1.3 1 0 0 1 1 1 1 Regulatory signalling modulator protein AmpE TMEM208_SND2 PF05620.11 AAZ35336.1 - 0.71 9.6 5.9 1.1 9.0 0.1 2.5 3 0 0 3 3 3 0 SRP-independent targeting protein 2/TMEM208 TPR_19 PF14559.6 AAZ35337.1 - 8.8e-20 71.0 23.0 2.3e-08 34.4 1.4 6.3 6 0 0 6 6 6 5 Tetratricopeptide repeat Response_reg PF00072.24 AAZ35337.1 - 1.7e-19 70.0 0.1 5.8e-19 68.3 0.0 1.9 2 0 0 2 2 2 1 Response regulator receiver domain TPR_8 PF13181.6 AAZ35337.1 - 8.7e-14 50.5 6.1 0.00078 19.5 0.1 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 AAZ35337.1 - 3.3e-13 49.2 19.0 0.003 18.2 0.5 7.7 4 1 4 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 AAZ35337.1 - 2.1e-10 39.9 15.5 0.0048 16.9 0.4 6.3 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 AAZ35337.1 - 2.2e-07 30.4 7.6 0.037 13.8 0.2 5.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 AAZ35337.1 - 2.4e-07 31.3 9.6 7.4e-06 26.5 1.5 5.1 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 AAZ35337.1 - 3.3e-07 30.5 11.0 0.0021 18.3 0.4 5.3 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 AAZ35337.1 - 1.7e-06 27.6 0.5 0.051 13.3 0.1 4.8 4 1 1 5 5 5 1 TPR repeat TPR_4 PF07721.14 AAZ35337.1 - 1.9e-06 27.9 1.7 0.15 12.8 0.2 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 AAZ35337.1 - 1.3e-05 24.9 1.6 0.031 14.3 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 AAZ35337.1 - 0.00026 21.4 6.7 0.31 11.8 0.1 5.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_21 PF09976.9 AAZ35337.1 - 0.0025 17.6 11.9 0.013 15.2 0.2 3.4 4 0 0 4 4 3 2 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 AAZ35337.1 - 0.0063 16.4 3.4 0.21 11.5 0.2 4.2 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 AAZ35337.1 - 0.028 14.8 5.6 5.4 7.6 0.3 4.3 4 0 0 4 4 3 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 AAZ35337.1 - 0.084 12.9 0.0 0.57 10.2 0.0 2.3 2 0 0 2 2 2 0 Mad3/BUB1 homology region 1 Wzy_C_2 PF11846.8 AAZ35337.1 - 0.088 12.7 0.3 0.088 12.7 0.3 2.4 3 0 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal TPR_5 PF12688.7 AAZ35337.1 - 0.13 12.5 5.4 0.23 11.7 0.4 3.6 3 1 1 4 4 4 0 Tetratrico peptide repeat DUF4726 PF15855.5 AAZ35337.1 - 0.18 12.0 0.9 5.1 7.4 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4726) TPR_9 PF13371.6 AAZ35337.1 - 0.64 10.2 4.4 0.43 10.8 0.4 2.9 2 2 1 3 3 2 0 Tetratricopeptide repeat MarR PF01047.22 AAZ35338.1 - 6.4e-16 58.0 0.0 1.5e-15 56.8 0.0 1.6 2 0 0 2 2 2 1 MarR family MarR_2 PF12802.7 AAZ35338.1 - 7.8e-09 35.3 0.0 1.3e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 AAZ35338.1 - 1.4e-05 25.5 0.1 2.4e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain PadR PF03551.14 AAZ35338.1 - 0.00014 21.7 0.0 0.00025 20.9 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_34 PF13601.6 AAZ35338.1 - 0.0022 18.1 0.0 0.0034 17.5 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain TFIIE_alpha PF02002.17 AAZ35338.1 - 0.0027 17.5 0.0 0.0056 16.5 0.0 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit HxlR PF01638.17 AAZ35338.1 - 0.0041 17.0 0.3 0.013 15.4 0.0 1.9 2 0 0 2 2 2 1 HxlR-like helix-turn-helix Penicillinase_R PF03965.16 AAZ35338.1 - 0.026 14.8 0.0 0.047 14.0 0.0 1.4 1 0 0 1 1 1 0 Penicillinase repressor HTH_20 PF12840.7 AAZ35338.1 - 0.034 14.2 0.0 0.073 13.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain TrmB PF01978.19 AAZ35338.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HlyD_3 PF13437.6 AAZ35339.1 - 3.6e-18 66.2 0.1 1e-16 61.5 0.1 2.6 2 0 0 2 2 2 1 HlyD family secretion protein HlyD PF00529.20 AAZ35339.1 - 1.9e-12 46.9 0.0 8.1e-12 44.9 0.0 1.9 2 1 0 2 2 2 1 HlyD membrane-fusion protein of T1SS HlyD_D23 PF16576.5 AAZ35339.1 - 1.2e-08 34.5 3.2 8.3e-06 25.2 0.3 2.5 2 1 0 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 AAZ35339.1 - 9e-06 25.4 1.0 3.4e-05 23.6 0.2 2.4 2 0 0 2 2 2 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AAZ35339.1 - 5.9e-05 22.8 0.3 0.038 13.8 0.0 2.5 2 0 0 2 2 2 2 Biotin-requiring enzyme DivIC PF04977.15 AAZ35339.1 - 0.089 12.6 17.3 2 8.2 0.3 4.1 2 1 3 5 5 5 0 Septum formation initiator Spc7 PF08317.11 AAZ35339.1 - 0.13 11.1 19.0 0.74 8.6 5.7 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein Troponin PF00992.20 AAZ35339.1 - 1.6 9.1 8.8 1.2 9.4 1.6 2.4 1 1 1 2 2 2 0 Troponin Tup_N PF08581.10 AAZ35339.1 - 1.7 9.0 14.0 1.7 9.0 1.4 3.2 3 1 0 3 3 3 0 Tup N-terminal XhlA PF10779.9 AAZ35339.1 - 1.9 8.7 9.7 0.17 12.1 3.4 2.6 3 0 0 3 3 2 0 Haemolysin XhlA Atg14 PF10186.9 AAZ35339.1 - 2.1 7.4 17.4 13 4.8 17.4 1.9 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF5082 PF16888.5 AAZ35339.1 - 8.1 6.7 21.1 2.4 8.5 2.2 4.1 2 1 1 4 4 4 0 Domain of unknown function (DUF5082) AvrB_AvrC PF05394.11 AAZ35340.1 - 4.6e-148 492.7 0.2 5.2e-148 492.6 0.2 1.0 1 0 0 1 1 1 1 Avirulence protein SUFU PF05076.13 AAZ35341.1 - 1.6e-20 73.8 0.0 1.9e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 Suppressor of fused protein (SUFU) Methyltransf_25 PF13649.6 AAZ35342.1 - 1.3e-10 41.8 0.0 2.9e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAZ35342.1 - 2.3e-09 37.8 0.0 8.1e-09 36.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAZ35342.1 - 2.6e-09 37.1 0.0 4.3e-08 33.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAZ35342.1 - 7.8e-07 29.1 0.0 2.6e-06 27.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AAZ35342.1 - 8.2e-06 25.5 0.0 0.00014 21.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.12 AAZ35342.1 - 1.5e-05 25.7 0.0 5.1e-05 24.0 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.18 AAZ35342.1 - 0.0004 19.8 0.0 0.00059 19.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_32 PF13679.6 AAZ35342.1 - 0.00082 19.4 0.0 0.0013 18.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 AAZ35342.1 - 0.0028 17.1 0.0 0.0044 16.5 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Prok-RING_1 PF14446.6 AAZ35342.1 - 0.053 13.5 0.2 0.097 12.6 0.2 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Methyltransf_18 PF12847.7 AAZ35342.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 AAZ35342.1 - 0.16 11.7 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) adh_short PF00106.25 AAZ35343.1 - 4.1e-30 104.7 0.0 5.2e-30 104.4 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAZ35343.1 - 2.8e-22 79.4 0.1 3.4e-22 79.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAZ35343.1 - 7.3e-07 29.3 0.2 1e-06 28.8 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AAZ35343.1 - 0.018 14.5 0.0 0.026 14.0 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 AAZ35343.1 - 0.055 13.0 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Glyco_transf_4 PF13439.6 AAZ35343.1 - 0.068 13.2 0.5 0.32 11.0 0.0 2.2 2 2 1 3 3 3 0 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AAZ35343.1 - 0.34 11.3 2.8 0.74 10.2 2.8 1.9 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain DUF3418 PF11898.8 AAZ35344.1 - 2.2e-194 647.4 4.8 3.4e-194 646.8 4.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3418) OB_NTP_bind PF07717.16 AAZ35344.1 - 8.4e-20 70.9 0.0 1.8e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 AAZ35344.1 - 2.2e-18 66.5 0.0 5.7e-18 65.2 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 AAZ35344.1 - 6.4e-13 49.0 0.0 1.7e-12 47.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 AAZ35344.1 - 3.3e-05 23.7 0.0 0.00011 22.0 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 AAZ35344.1 - 3.4e-05 24.2 0.0 0.0001 22.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 AAZ35344.1 - 0.00039 19.6 0.0 0.00079 18.6 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 AAZ35344.1 - 0.00059 20.1 0.1 0.0028 17.9 0.1 2.2 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AAZ35344.1 - 0.001 18.8 0.0 0.0028 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 AAZ35344.1 - 0.002 17.7 0.2 0.035 13.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 AAZ35344.1 - 0.0099 15.8 0.1 0.0099 15.8 0.1 2.6 3 1 0 3 3 3 1 NACHT domain DUF2075 PF09848.9 AAZ35344.1 - 0.026 13.8 0.0 0.052 12.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 AAZ35344.1 - 0.05 13.6 0.0 12 5.8 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit HisKA PF00512.25 AAZ35344.1 - 0.077 13.0 4.5 2.2 8.4 0.3 4.0 4 0 0 4 4 4 0 His Kinase A (phospho-acceptor) domain SRP54 PF00448.22 AAZ35344.1 - 0.094 12.3 0.5 1.1 8.8 0.0 2.5 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain DUF2057 PF09829.9 AAZ35344.1 - 0.15 12.2 1.3 3.1 7.9 0.3 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) AAA_23 PF13476.6 AAZ35344.1 - 0.17 12.4 0.0 0.41 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 AAZ35345.1 - 6.5e-69 231.8 0.0 4.7e-37 127.5 0.0 2.1 2 0 0 2 2 2 2 KaiC AAA_25 PF13481.6 AAZ35345.1 - 1.4e-12 47.6 2.0 2.4e-06 27.2 0.1 3.4 2 2 0 2 2 2 2 AAA domain GvpD PF07088.11 AAZ35345.1 - 2e-11 43.2 0.3 1.1e-08 34.2 0.0 2.9 3 0 0 3 3 3 1 GvpD gas vesicle protein RecA PF00154.21 AAZ35345.1 - 2.9e-10 40.1 0.1 0.0001 21.9 0.0 2.2 2 0 0 2 2 2 2 recA bacterial DNA recombination protein AAA_16 PF13191.6 AAZ35345.1 - 4.9e-10 40.1 0.4 3.1e-05 24.4 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain IstB_IS21 PF01695.17 AAZ35345.1 - 1.1e-08 35.1 0.0 0.0023 17.7 0.0 2.9 4 0 0 4 4 2 2 IstB-like ATP binding protein DnaB_C PF03796.15 AAZ35345.1 - 7.5e-08 32.0 0.0 0.023 14.0 0.0 3.7 3 2 0 3 3 3 2 DnaB-like helicase C terminal domain MEDS PF14417.6 AAZ35345.1 - 1e-06 28.7 0.0 0.014 15.2 0.0 2.3 2 0 0 2 2 2 2 MEDS: MEthanogen/methylotroph, DcmR Sensory domain AAA_22 PF13401.6 AAZ35345.1 - 2.3e-06 27.9 2.3 0.006 16.9 0.1 3.0 2 2 0 2 2 2 2 AAA domain AAA_30 PF13604.6 AAZ35345.1 - 3.7e-06 26.8 0.2 0.005 16.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 AAZ35345.1 - 9.8e-06 25.6 1.3 0.021 14.8 0.0 2.7 2 1 0 2 2 2 2 NACHT domain AAA_18 PF13238.6 AAZ35345.1 - 1.1e-05 26.0 0.1 0.29 11.7 0.0 2.5 2 1 0 2 2 2 2 AAA domain Rad51 PF08423.11 AAZ35345.1 - 1.9e-05 24.1 0.1 0.069 12.4 0.1 2.4 2 0 0 2 2 2 2 Rad51 AAA_24 PF13479.6 AAZ35345.1 - 3.2e-05 23.7 0.0 0.15 11.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 AAZ35345.1 - 4.7e-05 23.0 1.7 0.011 15.5 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF2075 PF09848.9 AAZ35345.1 - 5.7e-05 22.5 0.0 0.14 11.4 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) TrwB_AAD_bind PF10412.9 AAZ35345.1 - 6.9e-05 21.9 0.2 0.037 12.9 0.0 3.0 3 0 0 3 3 3 1 Type IV secretion-system coupling protein DNA-binding domain T2SSE PF00437.20 AAZ35345.1 - 0.00012 21.3 0.3 0.015 14.4 0.1 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_19 PF13245.6 AAZ35345.1 - 0.00012 22.4 0.1 0.025 14.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain PAXNEB PF05625.11 AAZ35345.1 - 0.00012 21.3 0.8 0.013 14.7 0.1 2.9 3 0 0 3 3 3 1 PAXNEB protein cobW PF02492.19 AAZ35345.1 - 0.00068 19.3 0.5 0.22 11.1 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 AAZ35345.1 - 0.00068 19.7 0.0 0.35 10.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 AAZ35345.1 - 0.0032 17.0 0.0 1.5 8.3 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 AAZ35345.1 - 0.004 17.3 0.1 4.2 7.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 AAZ35345.1 - 0.0051 16.8 0.1 2.8 8.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) BAR PF03114.18 AAZ35345.1 - 0.0068 16.1 0.1 0.03 14.0 0.0 1.9 2 0 0 2 2 2 1 BAR domain Viral_helicase1 PF01443.18 AAZ35345.1 - 0.0073 16.1 0.3 4.5 6.9 0.0 2.6 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA PF00004.29 AAZ35345.1 - 0.0077 16.7 1.4 7 7.1 0.6 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 AAZ35345.1 - 0.012 16.2 0.2 8.7 6.9 0.0 2.7 2 1 0 2 2 2 0 ABC transporter PhoH PF02562.16 AAZ35345.1 - 0.013 14.9 0.9 0.85 9.0 0.5 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_11 PF13086.6 AAZ35345.1 - 0.016 15.0 0.0 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 AAZ35345.1 - 0.018 15.3 0.4 4.7 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 AAZ35345.1 - 0.02 14.9 0.2 3.2 7.8 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP_bind_1 PF03029.17 AAZ35345.1 - 0.036 13.8 0.1 0.42 10.4 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 AAZ35345.1 - 0.051 12.9 0.1 2.8 7.2 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin DEAD PF00270.29 AAZ35345.1 - 0.073 12.8 0.1 1.3 8.8 0.0 2.6 2 1 0 2 2 2 0 DEAD/DEAH box helicase SRP54 PF00448.22 AAZ35345.1 - 0.086 12.5 0.3 1.6 8.3 0.1 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 AAZ35345.1 - 0.11 12.4 1.3 3.1 7.7 0.2 2.5 2 0 0 2 2 2 0 NTPase CbiA PF01656.23 AAZ35345.1 - 0.11 12.5 0.1 1.8 8.7 0.0 2.6 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain DAP3 PF10236.9 AAZ35345.1 - 0.14 11.3 0.1 8.7 5.4 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_23 PF13476.6 AAZ35345.1 - 0.16 12.4 1.7 3 8.3 0.2 2.3 2 0 0 2 2 2 0 AAA domain SH3_3 PF08239.11 AAZ35346.1 - 6.1e-10 39.2 0.1 1.4e-09 38.1 0.1 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain FlxA PF14282.6 AAZ35346.1 - 0.00015 21.7 2.9 0.00023 21.1 2.9 1.2 1 0 0 1 1 1 1 FlxA-like protein SH3_4 PF06347.13 AAZ35346.1 - 0.00037 20.3 0.0 0.00083 19.1 0.0 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain Jnk-SapK_ap_N PF09744.9 AAZ35346.1 - 0.00041 20.6 0.8 0.00057 20.1 0.8 1.2 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 DUF745 PF05335.13 AAZ35346.1 - 0.0034 17.1 0.7 0.0048 16.6 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF745) DUF4407 PF14362.6 AAZ35346.1 - 0.0089 15.4 0.2 0.012 14.9 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Bacillus_HBL PF05791.11 AAZ35346.1 - 0.0099 15.7 0.6 0.014 15.2 0.6 1.2 1 0 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) DUF4140 PF13600.6 AAZ35346.1 - 0.011 16.2 4.9 4.1 7.9 4.9 2.2 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) PRKG1_interact PF15898.5 AAZ35346.1 - 0.012 16.5 3.1 0.018 15.9 3.1 1.2 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Spc7 PF08317.11 AAZ35346.1 - 0.013 14.4 2.7 0.018 13.9 2.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 AAZ35346.1 - 0.019 15.0 0.7 0.027 14.5 0.7 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_MLP1_2 PF07926.12 AAZ35346.1 - 0.022 14.8 1.5 0.022 14.8 1.5 1.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Golgin_A5 PF09787.9 AAZ35346.1 - 0.024 14.1 0.6 0.028 13.9 0.6 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 IFT57 PF10498.9 AAZ35346.1 - 0.034 13.1 1.6 0.51 9.2 1.6 1.9 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF3584 PF12128.8 AAZ35346.1 - 0.04 11.5 1.6 0.05 11.1 1.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1664 PF07889.12 AAZ35346.1 - 0.049 13.7 1.7 0.071 13.1 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) GAS PF13851.6 AAZ35346.1 - 0.051 12.9 2.7 0.068 12.5 2.4 1.3 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Cluap1 PF10234.9 AAZ35346.1 - 0.054 12.9 0.6 0.061 12.7 0.6 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 Atg14 PF10186.9 AAZ35346.1 - 0.054 12.6 0.7 0.078 12.1 0.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FliT PF05400.13 AAZ35346.1 - 0.066 14.0 4.1 0.11 13.4 4.1 1.3 1 0 0 1 1 1 0 Flagellar protein FliT ATG16 PF08614.11 AAZ35346.1 - 0.077 13.2 7.7 0.22 11.7 8.2 1.3 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Noelin-1 PF12308.8 AAZ35346.1 - 0.095 12.7 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 Neurogenesis glycoprotein Fib_alpha PF08702.10 AAZ35346.1 - 0.13 12.5 0.2 0.18 12.0 0.2 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family SKA2 PF16740.5 AAZ35346.1 - 0.14 12.0 2.4 0.35 10.7 1.9 1.8 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 ABC_tran_CTD PF16326.5 AAZ35346.1 - 0.14 12.4 4.7 1.7 9.0 0.6 2.2 1 1 1 2 2 2 0 ABC transporter C-terminal domain Fmp27_WPPW PF10359.9 AAZ35346.1 - 0.15 10.9 0.8 0.2 10.5 0.8 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Seryl_tRNA_N PF02403.22 AAZ35346.1 - 0.15 12.3 2.3 1.5 9.1 1.3 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain UPF0242 PF06785.11 AAZ35346.1 - 0.2 11.8 1.9 0.28 11.3 1.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus NPV_P10 PF05531.12 AAZ35346.1 - 0.2 12.1 3.4 0.69 10.4 3.4 1.9 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 AAZ35346.1 - 0.38 11.1 3.4 1.4 9.2 1.6 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DHR10 PF18595.1 AAZ35346.1 - 0.38 10.8 6.8 0.68 10.0 6.8 1.3 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain CHASE3 PF05227.13 AAZ35346.1 - 0.39 10.6 6.4 0.59 10.0 6.4 1.2 1 0 0 1 1 1 0 CHASE3 domain OmpH PF03938.14 AAZ35346.1 - 0.5 10.7 5.2 0.9 9.9 5.2 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Sec2p PF06428.11 AAZ35346.1 - 0.77 9.8 4.8 2.5 8.1 4.8 1.8 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p DUF349 PF03993.12 AAZ35346.1 - 0.96 9.8 5.4 3.6 7.9 5.6 1.8 1 1 0 1 1 1 0 Domain of Unknown Function (DUF349) SlyX PF04102.12 AAZ35346.1 - 2.1 9.1 7.3 14 6.4 2.8 2.2 1 1 1 2 2 2 0 SlyX FAD_binding_3 PF01494.19 AAZ35347.1 - 1.2e-29 103.7 0.6 1.7e-29 103.2 0.6 1.1 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 AAZ35347.1 - 4.5e-10 39.1 3.9 1.6e-06 27.5 1.9 3.2 2 1 0 2 2 2 2 Lycopene cyclase protein SE PF08491.10 AAZ35347.1 - 5.7e-08 32.2 0.0 4.3e-07 29.3 0.0 1.9 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_2 PF07992.14 AAZ35347.1 - 8.9e-06 25.1 0.1 0.024 13.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAZ35347.1 - 0.00036 21.0 0.2 0.07 13.7 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AAZ35347.1 - 0.0011 18.6 7.8 0.0023 17.6 3.2 2.3 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 AAZ35347.1 - 0.0024 17.2 0.0 0.095 11.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AAZ35347.1 - 0.0024 18.0 1.3 0.0061 16.8 1.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 AAZ35347.1 - 0.0065 15.9 0.1 0.011 15.1 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.16 AAZ35347.1 - 0.0067 16.1 0.1 0.018 14.7 0.1 1.7 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.6 AAZ35347.1 - 0.019 15.0 0.4 2 8.4 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Rossmann-like PF10727.9 AAZ35347.1 - 0.028 14.3 0.4 0.085 12.7 0.4 1.8 1 0 0 1 1 1 0 Rossmann-like domain TrkA_N PF02254.18 AAZ35347.1 - 0.031 14.5 0.0 0.081 13.2 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.14 AAZ35347.1 - 0.032 12.9 0.6 3.6 6.2 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein 2-Hacid_dh_C PF02826.19 AAZ35347.1 - 0.046 13.1 0.1 0.11 11.9 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 AAZ35347.1 - 0.058 13.3 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 AAZ35347.1 - 0.066 12.3 8.1 0.019 14.0 4.4 1.9 1 1 1 2 2 2 0 FAD binding domain Trp_halogenase PF04820.14 AAZ35347.1 - 0.097 11.5 3.1 0.95 8.2 0.1 2.6 2 1 0 2 2 2 0 Tryptophan halogenase UDPG_MGDP_dh_N PF03721.14 AAZ35347.1 - 0.099 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Epimerase PF01370.21 AAZ35347.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ThiF PF00899.21 AAZ35347.1 - 0.15 11.4 1.6 0.24 10.7 1.6 1.3 1 0 0 1 1 1 0 ThiF family AlaDh_PNT_C PF01262.21 AAZ35347.1 - 0.16 11.2 0.1 0.28 10.5 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 AAZ35347.1 - 0.19 11.8 0.0 0.38 10.8 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DXP_synthase_N PF13292.6 AAZ35348.1 - 1.2e-119 398.6 0.0 2.6e-119 397.5 0.0 1.6 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.24 AAZ35348.1 - 5.4e-37 127.2 0.0 1.1e-36 126.2 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 AAZ35348.1 - 3e-27 94.9 0.7 6.5e-27 93.9 0.5 1.7 2 0 0 2 2 2 1 Transketolase, C-terminal domain E1_dh PF00676.20 AAZ35348.1 - 1.3e-05 24.3 0.1 2.1e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 AAZ35348.1 - 1.4e-05 24.9 0.2 7.2e-05 22.6 0.1 2.2 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_N PF00456.21 AAZ35348.1 - 0.0027 16.7 0.1 0.062 12.2 0.3 2.4 2 1 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Ribosomal_L20 PF00453.18 AAZ35350.1 - 2e-49 166.1 9.7 2.3e-49 165.9 9.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L20 OTCace PF00185.24 AAZ35351.1 - 5.7e-51 172.7 0.0 8.8e-51 172.1 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 AAZ35351.1 - 1.3e-36 125.8 0.0 2.2e-36 125.1 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain SBP_bac_8 PF13416.6 AAZ35352.1 - 1e-33 117.4 3.6 1.3e-33 117.0 3.6 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AAZ35352.1 - 6.2e-24 84.8 0.6 9.2e-24 84.2 0.6 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AAZ35352.1 - 8e-16 58.9 7.1 1.2e-15 58.3 7.1 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 AAZ35352.1 - 1.5e-07 31.4 0.0 6.4e-07 29.3 0.0 2.3 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein Lipoprotein_8 PF02030.15 AAZ35352.1 - 1.7e-06 27.1 0.8 0.00033 19.5 0.1 2.1 2 0 0 2 2 2 2 Hypothetical lipoprotein (MG045 family) Acetyltransf_1 PF00583.25 AAZ35353.1 - 0.00017 21.8 0.0 0.00027 21.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAZ35353.1 - 0.00028 21.2 0.0 0.00063 20.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAZ35353.1 - 0.00083 19.3 0.0 0.011 15.6 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 AAZ35353.1 - 0.035 13.8 0.0 0.092 12.4 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain LysR_substrate PF03466.20 AAZ35355.1 - 2.3e-35 121.9 0.4 4.3e-35 121.0 0.1 1.6 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ35355.1 - 9.8e-23 79.9 2.5 1.8e-22 79.1 2.5 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 AAZ35355.1 - 0.009 15.9 0.5 0.051 13.5 0.1 2.1 2 0 0 2 2 2 1 MarR family HTH_24 PF13412.6 AAZ35355.1 - 0.025 14.2 0.0 0.049 13.2 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 AAZ35355.1 - 0.096 12.5 0.4 0.19 11.5 0.4 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_11 PF08279.12 AAZ35355.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 HTH domain HTH_Mga PF08280.11 AAZ35355.1 - 0.16 12.0 0.0 0.39 10.8 0.0 1.6 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain HTH_5 PF01022.20 AAZ35355.1 - 0.16 11.8 0.1 0.39 10.6 0.1 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 AAZ35355.1 - 0.21 11.7 1.7 0.72 10.0 0.2 2.3 1 1 1 2 2 2 0 Helix-turn-helix domain Aldedh PF00171.22 AAZ35356.1 - 2.7e-149 497.6 0.0 3e-149 497.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family UvrD-helicase PF00580.21 AAZ35357.1 - 5.2e-56 190.4 0.0 9.5e-55 186.3 0.0 2.2 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 AAZ35357.1 - 5.7e-20 72.0 0.0 9.2e-11 41.7 0.0 3.2 1 1 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 AAZ35357.1 - 4e-18 66.1 0.0 1.6e-17 64.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 AAZ35357.1 - 9.2e-10 38.2 0.1 0.0007 19.4 0.0 2.8 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain PDDEXK_1 PF12705.7 AAZ35357.1 - 7.1e-07 29.4 0.0 7.6e-06 26.0 0.0 2.8 2 1 0 2 2 2 1 PD-(D/E)XK nuclease superfamily AAA_30 PF13604.6 AAZ35357.1 - 0.00074 19.3 0.1 0.024 14.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 AAZ35357.1 - 0.0074 16.1 0.0 0.024 14.4 0.0 1.8 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 AAZ35357.1 - 0.023 15.0 0.1 9.8 6.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 AAZ35357.1 - 0.086 12.4 0.2 0.44 10.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain UbiA PF01040.18 AAZ35358.1 - 2.7e-58 197.2 24.2 3.7e-58 196.8 24.2 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family TonB_dep_Rec PF00593.24 AAZ35359.1 - 2.2e-67 229.0 30.7 2.2e-67 229.0 30.7 1.4 1 1 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AAZ35359.1 - 2.3e-15 57.1 1.4 5.6e-15 55.8 1.4 1.7 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain OmpA_membrane PF01389.17 AAZ35359.1 - 0.016 14.9 0.1 0.67 9.7 0.0 2.5 2 0 0 2 2 2 0 OmpA-like transmembrane domain AmpE PF17113.5 AAZ35360.1 - 9.8e-10 38.2 8.3 1.2e-09 37.9 8.3 1.1 1 0 0 1 1 1 1 Regulatory signalling modulator protein AmpE CobD_Cbib PF03186.13 AAZ35360.1 - 0.36 10.0 7.0 1.4 8.0 7.0 2.0 1 1 0 1 1 1 0 CobD/Cbib protein YceI PF04264.13 AAZ35361.1 - 4.5e-39 134.3 0.5 5.2e-39 134.1 0.5 1.0 1 0 0 1 1 1 1 YceI-like domain MFS_1 PF07690.16 AAZ35362.1 - 1e-13 50.9 38.5 1e-13 50.9 38.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily RmuC PF02646.16 AAZ35363.1 - 1.7e-105 352.3 2.7 1.7e-105 352.3 2.7 2.5 2 1 0 2 2 2 1 RmuC family Spc7 PF08317.11 AAZ35363.1 - 0.037 12.9 27.7 0.11 11.3 11.0 3.1 3 1 1 4 4 4 0 Spc7 kinetochore protein Dynein_C PF18199.1 AAZ35363.1 - 0.056 12.7 1.9 0.094 11.9 1.9 1.3 1 0 0 1 1 1 0 Dynein heavy chain C-terminal domain Matrilin_ccoil PF10393.9 AAZ35363.1 - 0.11 12.4 4.6 12 5.9 0.3 3.7 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin AAA_18 PF13238.6 AAZ35363.1 - 0.24 11.9 2.4 0.53 10.8 0.1 2.7 2 1 1 3 3 3 0 AAA domain DUF4407 PF14362.6 AAZ35363.1 - 0.44 9.8 30.3 0.056 12.8 15.6 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) TPD52 PF04201.15 AAZ35363.1 - 0.53 9.9 8.0 0.16 11.5 0.4 2.5 2 0 0 2 2 2 0 Tumour protein D52 family Mer2 PF09074.10 AAZ35363.1 - 0.61 9.9 5.5 0.38 10.5 3.2 1.7 2 0 0 2 2 2 0 Mer2 DivIC PF04977.15 AAZ35363.1 - 0.63 9.9 25.3 0.8 9.5 1.9 5.1 3 2 1 5 5 5 0 Septum formation initiator LMBR1 PF04791.16 AAZ35363.1 - 1 8.2 10.8 3 6.7 10.8 1.8 1 1 0 1 1 1 0 LMBR1-like membrane protein DUF4250 PF14056.6 AAZ35363.1 - 2.5 8.1 4.7 2.8 8.0 0.1 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF4250) DUF4618 PF15397.6 AAZ35363.1 - 3.5 7.0 15.8 28 4.0 15.7 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) PRKG1_interact PF15898.5 AAZ35363.1 - 4 8.4 25.3 3.9 8.4 14.4 3.6 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain Fib_alpha PF08702.10 AAZ35363.1 - 5.4 7.2 9.7 17 5.6 0.3 3.4 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 AAZ35363.1 - 6.2 6.9 12.8 4.2 7.4 1.2 3.5 2 1 3 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus CheW PF01584.19 AAZ35364.1 - 1.4e-32 112.2 0.0 2.5e-32 111.4 0.0 1.4 1 0 0 1 1 1 1 CheW-like domain Response_reg PF00072.24 AAZ35364.1 - 2e-14 53.7 0.3 4.4e-14 52.6 0.3 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Transposase_mut PF00872.18 AAZ35365.1 - 1.5e-117 392.7 0.0 1.9e-117 392.3 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ35365.1 - 7.7e-05 23.0 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain DUF4844 PF16133.5 AAZ35365.1 - 0.23 12.0 0.0 0.55 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) ABC_tran PF00005.27 AAZ35366.1 - 5e-30 104.8 0.1 6.5e-30 104.4 0.1 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAZ35366.1 - 0.00019 21.4 0.7 0.15 11.9 0.2 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AAZ35366.1 - 0.00024 20.8 0.3 0.00081 19.1 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AAZ35366.1 - 0.0004 20.7 0.1 0.002 18.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 AAZ35366.1 - 0.001 19.0 0.2 0.21 11.5 0.0 2.2 2 0 0 2 2 2 2 NACHT domain AAA_16 PF13191.6 AAZ35366.1 - 0.0019 18.6 1.9 0.0045 17.4 1.9 1.7 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AAZ35366.1 - 0.0021 18.0 0.0 0.0037 17.2 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase NTPase_1 PF03266.15 AAZ35366.1 - 0.011 15.7 0.0 1.4 8.8 0.0 2.1 2 0 0 2 2 2 0 NTPase SMC_N PF02463.19 AAZ35366.1 - 0.044 13.2 0.1 0.83 9.0 0.1 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 AAZ35366.1 - 0.086 12.4 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain Transgly_assoc PF04226.13 AAZ35367.1 - 5.6e-13 48.9 11.8 5.6e-13 48.9 11.8 2.2 1 1 1 2 2 2 1 Transglycosylase associated protein FecCD PF01032.18 AAZ35367.1 - 0.17 10.9 8.6 0.19 10.7 8.6 1.0 1 0 0 1 1 1 0 FecCD transport family FeoB_associated PF12669.7 AAZ35367.1 - 7.7 7.0 12.2 1.1 9.7 1.4 2.8 3 0 0 3 3 3 0 FeoB-associated Cys-rich membrane protein CTP_transf_1 PF01148.20 AAZ35367.1 - 9 6.0 11.4 0.82 9.4 4.2 1.9 2 0 0 2 2 2 0 Cytidylyltransferase family Proton_antipo_M PF00361.20 AAZ35368.1 - 5.9e-70 235.8 25.1 9.9e-70 235.0 25.1 1.3 1 0 0 1 1 1 1 Proton-conducting membrane transporter Aconitase_2_N PF06434.13 AAZ35369.1 - 2.6e-95 317.8 0.0 4e-95 317.3 0.0 1.3 1 0 0 1 1 1 1 Aconitate hydratase 2 N-terminus Aconitase_B_N PF11791.8 AAZ35369.1 - 1.4e-65 220.0 0.1 2.5e-65 219.2 0.1 1.4 1 0 0 1 1 1 1 Aconitate B N-terminal domain Aconitase PF00330.20 AAZ35369.1 - 1.7e-42 146.0 0.0 1.1e-40 140.1 0.0 2.3 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Ketoacyl-synt_C PF02801.22 AAZ35369.1 - 0.11 12.6 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain DUF72 PF01904.18 AAZ35370.1 - 1.2e-53 182.5 0.3 1.3e-53 182.3 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF72 MerR_2 PF13591.6 AAZ35370.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 MerR HTH family regulatory protein OprD PF03573.13 AAZ35371.1 - 4.3e-158 526.5 7.2 4.8e-158 526.3 7.2 1.0 1 0 0 1 1 1 1 outer membrane porin, OprD family Cys_Met_Meta_PP PF01053.20 AAZ35372.1 - 3.5e-142 473.5 0.0 4e-142 473.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 AAZ35372.1 - 8.5e-15 54.8 0.0 9.7e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 AAZ35372.1 - 5e-09 35.6 0.0 3.3e-08 32.9 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 AAZ35372.1 - 1.5e-07 31.0 3.0 1.2e-06 28.1 3.0 2.2 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 AAZ35372.1 - 3.3e-06 26.6 0.1 0.024 14.0 0.1 2.3 2 0 0 2 2 2 2 Beta-eliminating lyase GDC-P PF02347.16 AAZ35372.1 - 1.4e-05 24.1 0.1 1.9e-05 23.7 0.1 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein Met_gamma_lyase PF06838.11 AAZ35372.1 - 0.00043 18.9 0.0 0.00059 18.5 0.0 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase SelA PF03841.13 AAZ35372.1 - 0.13 11.2 0.8 1 8.3 0.8 2.1 1 1 0 1 1 1 0 L-seryl-tRNA selenium transferase LysR_substrate PF03466.20 AAZ35373.1 - 2.8e-36 124.9 5.0 3.8e-36 124.4 5.0 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ35373.1 - 8.5e-19 67.3 1.2 1.9e-18 66.2 1.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family CcmF_C PF16327.5 AAZ35374.1 - 3e-122 408.0 12.0 3e-122 408.0 12.0 1.8 2 0 0 2 2 2 1 Cytochrome c-type biogenesis protein CcmF C-terminal Cytochrom_C_asm PF01578.20 AAZ35374.1 - 1.5e-54 185.0 22.1 1.5e-54 185.0 22.1 2.4 2 0 0 2 2 2 1 Cytochrome C assembly protein ResB PF05140.14 AAZ35374.1 - 0.15 10.8 1.3 10 4.7 0.2 2.4 1 1 1 2 2 2 0 ResB-like family Aminotran_3 PF00202.21 AAZ35375.1 - 1.2e-107 360.1 0.0 1.4e-107 359.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 AAZ35375.1 - 0.1 11.8 0.0 0.3 10.3 0.0 1.7 2 1 0 2 2 2 0 Beta-eliminating lyase G3P_acyltransf PF02660.15 AAZ35376.1 - 8.7e-51 172.2 4.3 9.9e-51 172.0 4.3 1.0 1 0 0 1 1 1 1 Glycerol-3-phosphate acyltransferase DUF1145 PF06611.12 AAZ35377.1 - 4.7e-19 68.1 5.4 6.5e-19 67.7 5.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1145) SpoIIIAC PF06686.11 AAZ35377.1 - 0.057 13.6 0.8 0.057 13.6 0.8 1.5 2 0 0 2 2 2 0 Stage III sporulation protein AC/AD protein family Secretin PF00263.21 AAZ35378.1 - 5.2e-50 169.4 1.2 8.2e-50 168.8 0.1 1.9 2 0 0 2 2 2 1 Bacterial type II and III secretion system protein Secretin_N PF03958.17 AAZ35378.1 - 9e-40 135.0 24.1 2.6e-15 56.6 11.9 4.1 3 1 0 3 3 3 3 Bacterial type II/III secretion system short domain DUF2797 PF10977.8 AAZ35379.1 - 2.4e-96 322.1 0.0 2.7e-96 321.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2797) Cript PF10235.9 AAZ35379.1 - 0.078 13.6 4.2 0.14 12.7 4.2 1.5 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT Bac_export_3 PF01313.19 AAZ35380.1 - 2.9e-26 91.2 10.5 3.7e-26 90.9 10.5 1.1 1 0 0 1 1 1 1 Bacterial export proteins, family 3 Phage_holin_1 PF04531.13 AAZ35380.1 - 0.39 11.3 2.9 0.49 11.0 2.9 1.2 1 0 0 1 1 1 0 Bacteriophage holin IucA_IucC PF04183.12 AAZ35381.1 - 3.9e-76 255.8 0.6 5.4e-76 255.3 0.1 1.5 2 0 0 2 2 2 1 IucA / IucC family FhuF PF06276.12 AAZ35381.1 - 2.8e-38 131.9 1.3 8.5e-38 130.3 0.3 2.1 2 0 0 2 2 2 1 Ferric iron reductase FhuF-like transporter cobW PF02492.19 AAZ35382.1 - 1.4e-36 125.7 0.0 2e-36 125.2 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 AAZ35382.1 - 0.027 14.7 0.0 0.069 13.4 0.0 1.6 2 1 0 2 2 2 0 AAA domain TsaE PF02367.17 AAZ35382.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 AAZ35382.1 - 0.2 11.8 0.0 0.37 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Aminotran_3 PF00202.21 AAZ35383.1 - 1.6e-92 310.3 0.0 2e-92 310.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 AAZ35383.1 - 0.0088 15.3 0.0 0.25 10.5 0.0 2.0 2 0 0 2 2 2 2 Aminotransferase class I and II Oxidored_FMN PF00724.20 AAZ35385.1 - 1.1e-79 268.2 0.0 1.3e-79 267.9 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Tautomerase PF01361.21 AAZ35385.1 - 0.17 11.8 0.0 0.4 10.6 0.0 1.5 1 0 0 1 1 1 0 Tautomerase enzyme DUF2875 PF11394.8 AAZ35386.1 - 1.8e-222 739.2 1.3 2.3e-222 738.8 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2875) PepSY_TM PF03929.16 AAZ35386.1 - 0.0045 16.7 0.6 0.0085 15.8 0.2 1.7 2 0 0 2 2 2 1 PepSY-associated TM region XhlA PF10779.9 AAZ35386.1 - 0.056 13.7 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 Haemolysin XhlA Phage_int_SAM_1 PF02899.17 AAZ35387.1 - 2.4e-06 27.7 0.0 5.3e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain PhoH PF02562.16 AAZ35388.1 - 7e-94 313.0 0.0 9.2e-94 312.6 0.0 1.1 1 0 0 1 1 1 1 PhoH-like protein AAA_30 PF13604.6 AAZ35388.1 - 1.1e-09 38.3 0.0 1.1e-08 35.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 AAZ35388.1 - 4.5e-06 27.1 0.0 5.5e-05 23.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 AAZ35388.1 - 0.0026 17.5 0.0 0.0061 16.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 AAZ35388.1 - 0.018 15.3 0.2 0.11 12.8 0.0 2.2 2 1 0 2 2 2 0 AAA domain DEAD PF00270.29 AAZ35388.1 - 0.06 13.1 0.0 0.65 9.7 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase ResIII PF04851.15 AAZ35388.1 - 0.11 12.4 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF2156 PF09924.9 AAZ35389.1 - 1.4e-90 303.3 0.0 1.9e-90 302.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) LPG_synthase_TM PF03706.13 AAZ35389.1 - 9.1e-12 45.1 45.0 9.1e-12 45.1 45.0 3.4 1 1 2 3 3 3 1 Lysylphosphatidylglycerol synthase TM region TPP_enzyme_C PF02775.21 AAZ35390.1 - 1.2e-38 132.3 0.1 3.2e-38 130.9 0.1 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.18 AAZ35390.1 - 1.5e-34 119.1 0.5 6.2e-34 117.1 0.2 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 AAZ35390.1 - 2.7e-32 111.4 0.1 5.3e-32 110.4 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain DUF3069 PF11269.8 AAZ35390.1 - 0.16 12.2 0.1 4.2 7.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3069) EAL PF00563.20 AAZ35391.1 - 3.9e-56 190.2 0.0 7.6e-56 189.3 0.0 1.4 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AAZ35391.1 - 3e-13 49.9 0.2 3.8e-12 46.3 0.0 2.5 2 1 0 2 2 2 1 Diguanylate cyclase, GGDEF domain CBS PF00571.28 AAZ35391.1 - 3.8e-08 33.6 0.0 2.9e-05 24.4 0.0 2.6 2 0 0 2 2 2 2 CBS domain DUF1513 PF07433.11 AAZ35392.1 - 2.7e-112 374.8 0.1 3.4e-112 374.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1513) Lactonase PF10282.9 AAZ35392.1 - 0.00066 19.0 0.0 0.035 13.4 0.0 2.1 2 0 0 2 2 2 2 Lactonase, 7-bladed beta-propeller Defensin_5 PF18251.1 AAZ35392.1 - 0.14 12.2 0.1 0.27 11.3 0.1 1.4 1 0 0 1 1 1 0 Fungal defensin Copsin Aminotran_3 PF00202.21 AAZ35393.1 - 5.6e-102 341.4 0.0 6.7e-102 341.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 AAZ35393.1 - 0.038 13.1 0.0 0.2 10.8 0.0 1.9 2 0 0 2 2 2 0 Aminotransferase class I and II ThiC_Rad_SAM PF01964.18 AAZ35394.1 - 2.9e-198 658.8 0.0 3.8e-198 658.4 0.0 1.1 1 0 0 1 1 1 1 Radical SAM ThiC family ThiC-associated PF13667.6 AAZ35394.1 - 5.6e-32 109.4 0.3 3.5e-31 106.9 0.2 2.3 2 0 0 2 2 2 1 ThiC-associated domain FixQ PF05545.11 AAZ35395.1 - 2.5e-09 37.0 0.1 3.3e-09 36.6 0.1 1.1 1 0 0 1 1 1 1 Cbb3-type cytochrome oxidase component FixQ Beta-lactamase PF00144.24 AAZ35396.1 - 1.7e-71 241.1 0.7 2.2e-71 240.8 0.7 1.0 1 0 0 1 1 1 1 Beta-lactamase Cyt_bd_oxida_I PF01654.17 AAZ35397.1 - 1.3e-169 564.3 24.8 1.5e-169 564.1 24.8 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit I DUF4235 PF14019.6 AAZ35397.1 - 0.00068 19.7 1.0 0.00068 19.7 1.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF4235) RecA PF00154.21 AAZ35398.1 - 0.00087 18.8 0.0 0.0012 18.4 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Epimerase PF01370.21 AAZ35399.1 - 1.9e-23 83.2 0.0 2.8e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1731 PF08338.11 AAZ35399.1 - 3.4e-19 68.4 0.6 6.4e-19 67.5 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) GDP_Man_Dehyd PF16363.5 AAZ35399.1 - 0.0016 17.9 0.0 0.32 10.3 0.0 2.5 3 0 0 3 3 3 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 AAZ35399.1 - 0.0022 17.2 0.0 0.0041 16.3 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_2 PF03446.15 AAZ35399.1 - 0.0045 17.2 0.0 0.0095 16.1 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 AAZ35399.1 - 0.021 15.4 0.0 0.044 14.4 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.25 AAZ35399.1 - 0.031 13.7 0.0 0.18 11.3 0.0 2.1 2 1 0 2 2 2 0 short chain dehydrogenase NAD_binding_10 PF13460.6 AAZ35399.1 - 0.04 13.8 0.0 0.055 13.4 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding KR PF08659.10 AAZ35399.1 - 0.071 13.0 0.1 0.22 11.4 0.1 1.8 1 0 0 1 1 1 0 KR domain NmrA PF05368.13 AAZ35399.1 - 0.079 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Glyco_trans_4_4 PF13579.6 AAZ35399.1 - 0.079 13.4 1.3 0.16 12.4 0.2 2.0 3 0 0 3 3 3 0 Glycosyl transferase 4-like domain DUF4203 PF13886.6 AAZ35401.1 - 0.016 14.9 12.9 0.021 14.5 12.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) DUF4231 PF14015.6 AAZ35401.1 - 3.2 8.3 4.3 1.3 9.5 1.8 1.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) DSBA PF01323.20 AAZ35402.1 - 3.5e-42 144.4 0.0 3.9e-42 144.2 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 AAZ35402.1 - 2.5e-06 27.8 0.2 8.9e-06 26.0 0.0 1.9 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.6 AAZ35402.1 - 0.00018 21.5 0.0 0.0012 18.8 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_5 PF13743.6 AAZ35402.1 - 0.017 14.8 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_2 PF13098.6 AAZ35402.1 - 0.034 14.6 0.0 0.96 9.9 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like domain DUF1525 PF07511.11 AAZ35402.1 - 0.096 12.8 0.1 0.23 11.6 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1525) DUF4350 PF14258.6 AAZ35402.1 - 0.14 12.6 0.1 1.5 9.3 0.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4350) TnsD PF15978.5 AAZ35403.1 - 0.059 12.3 0.0 0.065 12.2 0.0 1.1 1 0 0 1 1 1 0 Tn7-like transposition protein D HTH_35 PF13693.6 AAZ35403.1 - 0.06 13.4 0.0 0.078 13.0 0.0 1.1 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 AAZ35403.1 - 0.094 12.5 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Homeodomain-like domain Autotransporter PF03797.19 AAZ35404.1 - 1.9e-60 204.6 15.1 1.9e-60 204.6 15.1 3.9 2 1 1 3 3 3 1 Autotransporter beta-domain PATR PF12951.7 AAZ35404.1 - 3.9e-15 55.6 21.9 2.6e-09 37.0 12.9 6.5 7 0 0 7 7 7 2 Passenger-associated-transport-repeat PAP2 PF01569.21 AAZ35404.1 - 7.1e-12 45.3 0.0 1.5e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 PAP2 superfamily Viral_DNA_bp PF00747.17 AAZ35404.1 - 0.055 10.6 0.0 0.083 10.0 0.0 1.1 1 0 0 1 1 1 0 ssDNA binding protein Recep_L_domain PF01030.24 AAZ35404.1 - 0.08 13.1 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Receptor L domain AbrB PF05145.12 AAZ35406.1 - 1.3e-83 280.6 29.4 1.7e-83 280.2 29.4 1.1 1 0 0 1 1 1 1 Transition state regulatory protein AbrB Pro_isomerase PF00160.21 AAZ35407.1 - 4.2e-45 153.9 1.5 4.8e-45 153.6 1.5 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Bac_surface_Ag PF01103.23 AAZ35408.1 - 2.4e-91 306.6 15.2 3.7e-91 306.0 15.2 1.3 1 0 0 1 1 1 1 Surface antigen POTRA PF07244.15 AAZ35408.1 - 3.7e-68 226.1 5.4 4e-16 59.3 0.1 5.3 5 0 0 5 5 5 5 Surface antigen variable number repeat POTRA_1 PF08478.10 AAZ35408.1 - 8.5e-11 42.0 0.8 0.0051 17.1 0.0 4.8 5 0 0 5 5 5 3 POTRA domain, FtsQ-type POTRA_2 PF08479.11 AAZ35408.1 - 2.6e-06 27.2 0.7 2.7 7.9 0.0 5.3 4 1 0 4 4 4 2 POTRA domain, ShlB-type ShlB PF03865.13 AAZ35408.1 - 0.00066 19.2 5.9 0.00066 19.2 5.9 1.6 2 0 0 2 2 2 1 Haemolysin secretion/activation protein ShlB/FhaC/HecB YqfD PF06898.11 AAZ35408.1 - 0.0095 14.8 0.1 0.02 13.8 0.1 1.5 1 0 0 1 1 1 1 Putative stage IV sporulation protein YqfD ETF_alpha PF00766.19 AAZ35409.1 - 1.7e-23 82.5 1.9 1.7e-23 82.5 1.9 2.5 3 0 0 3 3 3 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.21 AAZ35409.1 - 1.3e-15 57.8 0.0 2.5e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein domain SBP_bac_8 PF13416.6 AAZ35410.1 - 4.7e-06 26.6 0.0 6.3e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AAZ35410.1 - 4.8e-05 22.9 0.1 0.0001 21.8 0.1 1.5 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein DUF4096 PF13340.6 AAZ35411.1 - 5.7e-25 87.3 0.4 1.5e-24 86.0 0.4 1.8 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1 PF01609.21 AAZ35411.1 - 1.3e-13 51.1 0.0 2.3e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AAZ35411.1 - 7e-10 39.2 0.2 2.1e-09 37.6 0.2 1.9 1 0 0 1 1 1 1 Transposase DDE domain HTH_Tnp_Tc3_2 PF01498.18 AAZ35411.1 - 0.061 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Transposase Baculo_LEF5_C PF11792.8 AAZ35412.1 - 0.14 11.8 0.1 0.18 11.5 0.1 1.3 1 1 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain GMC_oxred_N PF00732.19 AAZ35413.1 - 4.8e-97 324.9 0.0 6.6e-97 324.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 AAZ35413.1 - 3.8e-40 137.7 0.0 5.8e-40 137.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 AAZ35413.1 - 0.0015 18.7 0.4 0.0035 17.5 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 AAZ35413.1 - 0.0015 17.6 0.1 0.0023 17.1 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 AAZ35413.1 - 0.003 16.7 1.1 0.078 12.0 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 AAZ35413.1 - 0.0069 16.0 1.8 0.073 12.6 0.5 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 AAZ35413.1 - 0.013 14.7 0.0 0.027 13.7 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 AAZ35413.1 - 0.016 14.5 0.1 0.026 13.8 0.1 1.3 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.16 AAZ35413.1 - 0.055 13.1 0.2 0.097 12.3 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 AAZ35413.1 - 0.086 12.1 0.0 0.21 10.8 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 AAZ35413.1 - 0.2 10.3 0.2 0.31 9.7 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein Hpt PF01627.23 AAZ35414.1 - 1.3e-63 211.2 73.2 4.3e-14 52.5 0.6 10.7 9 3 1 10 10 10 7 Hpt domain Response_reg PF00072.24 AAZ35414.1 - 7e-29 100.3 0.8 1.9e-28 98.9 0.8 1.8 1 0 0 1 1 1 1 Response regulator receiver domain CheW PF01584.19 AAZ35414.1 - 7.7e-24 83.9 0.1 2.1e-23 82.5 0.1 1.9 1 0 0 1 1 1 1 CheW-like domain HATPase_c PF02518.26 AAZ35414.1 - 1.5e-13 51.2 0.1 3.5e-13 50.0 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase H-kinase_dim PF02895.14 AAZ35414.1 - 0.0094 16.3 9.9 0.018 15.4 7.3 3.1 2 1 0 2 2 2 1 Signal transducing histidine kinase, homodimeric domain HATPase_c_2 PF13581.6 AAZ35414.1 - 0.093 12.7 0.0 0.4 10.7 0.0 2.1 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain DUF4778 PF16008.5 AAZ35414.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) eIF-4B PF06273.11 AAZ35414.1 - 0.13 11.3 1.5 0.63 9.0 1.6 1.8 2 0 0 2 2 2 0 Plant specific eukaryotic initiation factor 4B MnmE_helical PF12631.7 AAZ35414.1 - 1.8 8.6 6.5 4.2 7.5 0.0 4.3 4 1 1 5 5 5 0 MnmE helical domain HisKA PF00512.25 AAZ35414.1 - 5.5 7.1 9.8 5.4 7.1 0.6 6.1 5 1 0 5 5 5 0 His Kinase A (phospho-acceptor) domain Semialdhyde_dhC PF02774.18 AAZ35415.1 - 1.9e-62 210.6 0.0 2.5e-62 210.2 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 AAZ35415.1 - 1.2e-25 90.3 0.0 2.5e-25 89.3 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain HNH PF01844.23 AAZ35416.1 - 2.3e-12 46.9 7.1 3.1e-12 46.5 7.1 1.2 1 0 0 1 1 1 1 HNH endonuclease Ima1_N PF09779.9 AAZ35416.1 - 0.0069 17.2 0.4 1.5 9.7 0.0 2.1 2 0 0 2 2 2 2 Ima1 N-terminal domain Abhydrolase_3 PF07859.13 AAZ35417.1 - 6.2e-44 150.4 0.0 7.6e-44 150.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAZ35417.1 - 2.2e-05 25.1 2.7 9.9e-05 23.0 2.7 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.28 AAZ35417.1 - 4.9e-05 22.4 0.3 0.0029 16.5 0.2 2.0 2 0 0 2 2 2 2 Carboxylesterase family Hydrolase_4 PF12146.8 AAZ35417.1 - 0.0079 15.5 0.2 0.16 11.2 0.1 2.7 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 AAZ35417.1 - 0.02 14.3 0.0 0.045 13.2 0.0 1.5 1 1 0 1 1 1 0 Prolyl oligopeptidase family DUF2920 PF11144.8 AAZ35417.1 - 0.021 14.0 0.0 5.1 6.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) CbiG_C PF01890.16 AAZ35418.1 - 1.7e-29 102.7 1.3 2.2e-29 102.4 1.3 1.1 1 0 0 1 1 1 1 Cobalamin synthesis G C-terminus EPSP_synthase PF00275.20 AAZ35419.1 - 3.2e-90 302.8 0.0 3.1e-63 213.9 0.0 2.0 1 1 1 2 2 2 2 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) CheW PF01584.19 AAZ35420.1 - 2e-27 95.5 0.1 4.6e-27 94.3 0.1 1.7 1 0 0 1 1 1 1 CheW-like domain Hpt PF01627.23 AAZ35420.1 - 6.5e-18 64.8 0.7 2e-17 63.2 0.7 1.9 1 1 0 1 1 1 1 Hpt domain HATPase_c PF02518.26 AAZ35420.1 - 3e-16 59.9 0.0 6.2e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase H-kinase_dim PF02895.14 AAZ35420.1 - 2.7e-08 34.1 0.1 7.4e-08 32.7 0.1 1.8 1 0 0 1 1 1 1 Signal transducing histidine kinase, homodimeric domain DUF1380 PF07128.12 AAZ35420.1 - 0.099 12.8 0.1 0.29 11.3 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1380) tRNA-synt_1g PF09334.11 AAZ35421.1 - 4.3e-157 522.9 0.0 5.3e-157 522.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA_bind PF01588.20 AAZ35421.1 - 1.2e-23 83.0 0.0 2.2e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain tRNA-synt_1 PF00133.22 AAZ35421.1 - 4e-11 41.9 0.2 2.7e-07 29.3 0.1 3.2 3 1 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 AAZ35421.1 - 1.7e-10 40.8 0.0 0.0002 20.8 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 AAZ35421.1 - 7.8e-06 25.0 0.0 0.00094 18.2 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (K) BMFP PF04380.13 AAZ35422.1 - 1.6e-24 86.2 0.9 1.9e-24 85.9 0.9 1.0 1 0 0 1 1 1 1 Membrane fusogenic activity DAGK_prokar PF01219.19 AAZ35423.1 - 1.4e-31 108.3 2.8 1.6e-31 108.1 2.8 1.0 1 0 0 1 1 1 1 Prokaryotic diacylglycerol kinase DUF4105 PF13387.6 AAZ35424.1 - 8.1e-30 103.7 0.0 1.5e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4105) Peptidase_M90 PF06167.12 AAZ35424.1 - 0.0066 16.1 0.2 0.064 12.9 0.0 2.2 2 0 0 2 2 2 1 Glucose-regulated metallo-peptidase M90 FliT PF05400.13 AAZ35424.1 - 3.5 8.5 8.1 0.47 11.3 3.2 2.1 2 0 0 2 2 2 0 Flagellar protein FliT LRR_8 PF13855.6 AAZ35425.1 - 3.1e-19 68.5 1.2 2.7e-06 27.1 0.3 3.8 2 1 1 3 3 3 3 Leucine rich repeat Pkinase_Tyr PF07714.17 AAZ35425.1 - 1.6e-17 63.7 0.0 8.3e-16 58.0 0.0 2.2 1 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 AAZ35425.1 - 7e-15 55.1 0.0 1.9e-13 50.4 0.0 2.1 1 1 1 2 2 2 1 Protein kinase domain LRR_4 PF12799.7 AAZ35425.1 - 2e-11 43.9 4.2 0.0001 22.6 0.4 4.6 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 AAZ35425.1 - 5e-07 29.4 0.3 0.00018 21.1 0.1 2.6 1 1 2 3 3 3 3 Leucine-rich repeat Kdo PF06293.14 AAZ35425.1 - 2.2e-06 27.2 0.0 3.6e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 AAZ35425.1 - 0.00011 22.2 0.7 0.001 19.1 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 AAZ35425.1 - 0.0069 16.0 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 AAZ35425.1 - 0.054 12.8 0.0 0.089 12.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like LRR_1 PF00560.33 AAZ35425.1 - 0.36 11.5 12.0 0.44 11.3 0.5 5.6 5 2 1 6 6 6 0 Leucine Rich Repeat GFO_IDH_MocA PF01408.22 AAZ35426.1 - 1.1e-17 64.9 0.1 2.6e-17 63.8 0.1 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CoA_binding_2 PF13380.6 AAZ35426.1 - 0.04 14.4 0.0 0.069 13.6 0.0 1.4 1 0 0 1 1 1 0 CoA binding domain Amidohydro_1 PF01979.20 AAZ35427.1 - 9.9e-34 117.2 0.0 1.3e-33 116.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Pterin_4a PF01329.19 AAZ35428.1 - 6.1e-28 96.8 0.0 7.2e-28 96.6 0.0 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase AI-2E_transport PF01594.16 AAZ35429.1 - 3.2e-64 217.2 39.4 3.9e-64 216.9 39.4 1.0 1 0 0 1 1 1 1 AI-2E family transporter EutB PF06751.11 AAZ35430.1 - 1.7e-221 735.6 0.0 2.1e-221 735.3 0.0 1.0 1 0 0 1 1 1 1 Ethanolamine ammonia lyase large subunit (EutB) SBP_bac_5 PF00496.22 AAZ35431.1 - 1.4e-57 195.4 0.4 1.7e-57 195.1 0.4 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle Ribonuc_L-PSP PF01042.21 AAZ35432.1 - 3.3e-24 85.2 0.0 3.7e-24 85.1 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP BON PF04972.17 AAZ35432.1 - 0.011 16.0 0.2 0.02 15.2 0.2 1.4 1 0 0 1 1 1 0 BON domain Asn_synthase PF00733.21 AAZ35432.1 - 0.14 11.8 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Asparagine synthase Ketoacyl-synt_2 PF13723.6 AAZ35433.1 - 1.2e-76 257.3 0.6 1.4e-76 257.1 0.6 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain IspD PF01128.19 AAZ35434.1 - 4.2e-65 219.6 0.0 5.2e-65 219.3 0.0 1.0 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NTP_transf_3 PF12804.7 AAZ35434.1 - 8.7e-08 32.7 1.2 1e-07 32.4 1.2 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF2145 PF09916.9 AAZ35434.1 - 0.015 15.0 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2145) Glyco_tranf_2_4 PF13704.6 AAZ35434.1 - 0.095 13.2 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 Ribosomal_S11 PF00411.19 AAZ35435.1 - 6.4e-51 171.4 0.3 7.6e-51 171.2 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 TSC22 PF01166.18 AAZ35436.1 - 1.3e-06 28.6 0.2 2.1e-06 27.9 0.2 1.3 1 0 0 1 1 1 1 TSC-22/dip/bun family TetR_N PF00440.23 AAZ35436.1 - 0.0013 18.5 0.2 0.0024 17.6 0.2 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family bZIP_1 PF00170.21 AAZ35436.1 - 0.018 15.1 1.3 0.033 14.3 1.3 1.5 1 0 0 1 1 1 0 bZIP transcription factor HALZ PF02183.18 AAZ35436.1 - 0.029 14.6 0.4 0.052 13.8 0.4 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper ZapB PF06005.12 AAZ35436.1 - 0.04 14.4 0.7 0.071 13.6 0.7 1.4 1 0 0 1 1 1 0 Cell division protein ZapB NRBF2 PF08961.10 AAZ35436.1 - 0.12 12.0 0.6 0.18 11.4 0.3 1.6 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator DivIC PF04977.15 AAZ35436.1 - 0.38 10.6 2.7 0.31 10.8 0.6 1.9 2 1 0 2 2 2 0 Septum formation initiator MCPsignal PF00015.21 AAZ35437.1 - 2.9e-44 150.9 27.6 2.9e-44 150.9 27.6 3.4 2 2 1 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Fib_alpha PF08702.10 AAZ35437.1 - 0.036 14.3 12.3 0.046 13.9 0.8 3.2 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family RPW8 PF05659.11 AAZ35437.1 - 0.1 12.3 0.1 3 7.5 0.0 2.7 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 ZapB PF06005.12 AAZ35437.1 - 0.72 10.3 9.6 13 6.3 0.7 4.1 4 0 0 4 4 4 0 Cell division protein ZapB Arfaptin PF06456.13 AAZ35437.1 - 1.2 8.6 6.7 2.6 7.6 0.0 3.4 4 0 0 4 4 4 0 Arfaptin-like domain OSCP PF00213.18 AAZ35437.1 - 2 8.5 11.3 0.3 11.2 0.5 3.9 3 2 1 4 4 4 0 ATP synthase delta (OSCP) subunit Mce4_CUP1 PF11887.8 AAZ35437.1 - 6.4 6.2 16.6 0.67 9.4 3.5 2.8 3 0 0 3 3 3 0 Cholesterol uptake porter CUP1 of Mce4, putative ExbD PF02472.16 AAZ35438.1 - 8.1e-31 106.9 0.1 9.4e-31 106.7 0.1 1.0 1 0 0 1 1 1 1 Biopolymer transport protein ExbD/TolR DHHA1 PF02272.19 AAZ35439.1 - 2.4e-28 99.3 0.0 3.8e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 DHHA1 domain RecJ_OB PF17768.1 AAZ35439.1 - 2e-19 69.8 0.0 3.2e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 RecJ OB domain DHH PF01368.20 AAZ35439.1 - 1.6e-07 31.5 0.0 2.7e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 DHH family SUI1 PF01253.22 AAZ35440.1 - 9.5e-18 64.5 0.1 1.3e-17 64.1 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 Acetyltransf_1 PF00583.25 AAZ35441.1 - 2.3e-14 53.6 0.1 2.7e-14 53.4 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AAZ35441.1 - 3.6e-10 39.9 0.0 4.4e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAZ35441.1 - 1.9e-09 37.8 0.1 2.5e-09 37.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AAZ35441.1 - 4.1e-05 23.6 0.0 0.0001 22.3 0.0 1.6 1 1 1 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 AAZ35441.1 - 0.00015 21.9 0.0 0.003 17.6 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AAZ35441.1 - 0.00093 19.9 0.0 0.0013 19.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 AAZ35441.1 - 0.0044 16.7 0.0 0.0045 16.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ FR47 PF08445.10 AAZ35441.1 - 0.005 16.8 0.0 0.0066 16.4 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_6 PF13480.7 AAZ35441.1 - 0.017 15.2 0.1 0.022 14.9 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 AAZ35441.1 - 0.12 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_13 PF13880.6 AAZ35441.1 - 0.12 12.3 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Ribosomal_L18p PF00861.22 AAZ35442.1 - 5.5e-41 139.6 4.4 6.2e-41 139.4 4.4 1.0 1 0 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast TGS PF02824.21 AAZ35442.1 - 0.031 14.3 0.3 0.049 13.7 0.3 1.5 1 1 0 1 1 1 0 TGS domain DUF3263 PF11662.8 AAZ35442.1 - 0.16 11.8 1.6 30 4.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3263) Urease_beta PF00699.20 AAZ35443.1 - 2.2e-45 152.6 0.0 2.5e-45 152.5 0.0 1.0 1 0 0 1 1 1 1 Urease beta subunit LppC PF04348.13 AAZ35444.1 - 5.7e-177 589.8 21.8 6.5e-177 589.6 21.8 1.0 1 0 0 1 1 1 1 LppC putative lipoprotein Peripla_BP_6 PF13458.6 AAZ35444.1 - 8.2e-06 25.7 8.7 8.2e-06 25.7 8.7 2.3 2 2 1 3 3 3 1 Periplasmic binding protein DUF4880 PF16220.5 AAZ35444.1 - 0.017 15.0 0.2 0.017 15.0 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4880) Tim44 PF04280.15 AAZ35445.1 - 1.2e-09 38.5 0.5 4.1e-09 36.7 0.5 1.8 1 1 0 1 1 1 1 Tim44-like domain RseC_MucC PF04246.12 AAZ35445.1 - 0.11 12.4 0.2 0.17 11.8 0.2 1.2 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Flavin_Reduct PF01613.18 AAZ35446.1 - 6.5e-13 49.0 0.0 8e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain EamA PF00892.20 AAZ35447.1 - 3.9e-23 82.2 35.3 4e-16 59.4 8.1 2.0 2 0 0 2 2 2 2 EamA-like transporter family RseC_MucC PF04246.12 AAZ35447.1 - 3.5 7.6 17.4 2.4 8.1 1.3 3.2 2 2 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC AAA_26 PF13500.6 AAZ35448.1 - 6.3e-37 127.3 0.0 7.6e-37 127.1 0.0 1.0 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 AAZ35448.1 - 1.2e-11 44.7 0.0 1.7e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF1611 PF07755.11 AAZ35448.1 - 0.032 13.5 0.4 0.12 11.7 0.1 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1611_C) P-loop domain GFO_IDH_MocA PF01408.22 AAZ35449.1 - 9.6e-29 100.7 0.0 1.7e-28 99.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 AAZ35449.1 - 0.039 14.5 0.0 0.1 13.2 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA_C PF02894.17 AAZ35449.1 - 0.05 13.6 0.0 0.095 12.7 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 AAZ35449.1 - 0.12 13.0 0.0 0.21 12.2 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain CxC7 PF18866.1 AAZ35449.1 - 0.21 11.7 0.0 0.44 10.7 0.0 1.5 1 0 0 1 1 1 0 CxC7 like cysteine cluster associated with KDZ transposases DUF1656 PF07869.12 AAZ35450.1 - 2.6e-21 75.4 8.7 3.1e-21 75.1 8.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1656) Ytca PF17090.5 AAZ35450.1 - 0.012 16.1 0.9 0.014 15.8 0.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family SBP_bac_6 PF13343.6 AAZ35451.1 - 1.4e-20 73.8 0.1 1.9e-20 73.3 0.1 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 AAZ35451.1 - 1.1e-19 71.3 0.7 1.5e-19 70.9 0.7 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AAZ35451.1 - 1e-15 58.5 0.3 2.1e-15 57.5 0.3 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 AAZ35451.1 - 4.1e-15 56.1 0.0 6.9e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein RdgC PF04381.12 AAZ35452.1 - 3.6e-115 384.3 0.2 4.1e-115 384.1 0.2 1.0 1 0 0 1 1 1 1 Putative exonuclease, RdgC MacB_PCD PF12704.7 AAZ35453.1 - 4.5e-14 53.3 0.3 9e-14 52.3 0.0 1.7 2 0 0 2 2 2 1 MacB-like periplasmic core domain FtsX PF02687.21 AAZ35453.1 - 1.8e-11 44.3 1.0 1.8e-11 44.3 1.0 3.2 3 0 0 3 3 3 1 FtsX-like permease family DUF3487 PF11990.8 AAZ35453.1 - 0.22 11.4 5.7 6.9 6.6 1.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) TMEM238 PF15125.6 AAZ35453.1 - 0.36 11.1 3.2 2.7 8.3 0.7 2.6 2 0 0 2 2 2 0 TMEM238 protein family Claudin_2 PF13903.6 AAZ35453.1 - 0.93 9.2 9.2 0.44 10.3 2.4 2.6 3 0 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction DUF4131 PF13567.6 AAZ35453.1 - 4 7.1 12.0 24 4.5 0.4 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Dala_Dala_lig_C PF07478.13 AAZ35454.1 - 8.4e-55 185.5 0.0 1e-54 185.2 0.0 1.1 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Dala_Dala_lig_N PF01820.21 AAZ35454.1 - 3.1e-20 72.6 0.2 1e-18 67.7 0.2 2.3 1 1 0 1 1 1 1 D-ala D-ala ligase N-terminus CPSase_L_D2 PF02786.17 AAZ35454.1 - 4.6e-09 36.1 0.0 4.6e-05 23.0 0.0 2.1 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.6 AAZ35454.1 - 2.5e-08 33.7 0.0 1.3e-07 31.3 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 AAZ35454.1 - 2.5e-06 27.2 0.0 1e-05 25.2 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 AAZ35454.1 - 1.7e-05 24.9 0.0 5.6e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain TTL PF03133.15 AAZ35454.1 - 0.011 14.9 0.0 0.21 10.7 0.0 2.0 2 0 0 2 2 2 0 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 AAZ35454.1 - 0.022 14.0 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 YheC/D like ATP-grasp ATPgrasp_Ter PF15632.6 AAZ35454.1 - 0.054 13.2 0.0 0.42 10.4 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon ATPgrasp_ST PF14397.6 AAZ35454.1 - 0.18 11.0 0.0 0.94 8.7 0.0 1.9 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Ribosomal_L34 PF00468.17 AAZ35455.1 - 3.1e-25 87.9 10.9 3.3e-25 87.8 10.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L34 HATPase_c PF02518.26 AAZ35457.1 - 6.2e-18 65.4 0.0 1.4e-17 64.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 AAZ35457.1 - 3.2e-08 33.8 0.2 1e-07 32.2 0.2 2.0 1 0 0 1 1 1 1 HAMP domain HisKA PF00512.25 AAZ35457.1 - 7.5e-08 32.3 0.1 1.6e-07 31.3 0.1 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 AAZ35457.1 - 0.027 14.4 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 GHKL domain HATPase_c_2 PF13581.6 AAZ35457.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain DUF58 PF01882.18 AAZ35458.1 - 1.3e-23 83.1 0.5 4.6e-23 81.3 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function DUF58 VWA_2 PF13519.6 AAZ35458.1 - 5.9e-06 26.9 0.0 1.1e-05 26.1 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF2795 PF11387.8 AAZ35458.1 - 0.28 11.4 1.1 1.2 9.4 0.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2795) QueC PF06508.13 AAZ35459.1 - 2.7e-80 268.8 0.0 3.1e-80 268.6 0.0 1.0 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 AAZ35459.1 - 8.1e-09 35.6 0.0 1.2e-08 35.1 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase Arginosuc_synth PF00764.19 AAZ35459.1 - 0.0027 17.1 0.0 0.004 16.5 0.0 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase NAD_synthase PF02540.17 AAZ35459.1 - 0.042 13.0 0.0 0.099 11.7 0.0 1.6 2 0 0 2 2 2 0 NAD synthase ThiI PF02568.14 AAZ35459.1 - 0.047 13.3 0.0 0.5 9.9 0.0 2.0 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.16 AAZ35459.1 - 0.094 11.5 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase PrmA PF06325.13 AAZ35460.1 - 1.4e-96 323.4 0.0 1.6e-96 323.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 AAZ35460.1 - 1.4e-10 40.9 0.0 2.3e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 AAZ35460.1 - 7.5e-08 32.3 0.0 1.1e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAZ35460.1 - 1.7e-06 28.6 0.0 4.1e-06 27.4 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAZ35460.1 - 0.00012 21.9 0.0 0.0003 20.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAZ35460.1 - 0.0003 21.4 0.0 0.00061 20.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAZ35460.1 - 0.00076 20.2 0.0 0.0017 19.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 AAZ35460.1 - 0.0013 18.4 0.0 0.002 17.8 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PCMT PF01135.19 AAZ35460.1 - 0.0033 17.2 0.0 0.0057 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.11 AAZ35460.1 - 0.015 14.2 0.0 0.021 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 AAZ35460.1 - 0.038 14.0 0.0 0.056 13.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain N6_N4_Mtase PF01555.18 AAZ35460.1 - 0.06 13.1 0.0 0.09 12.5 0.0 1.2 1 0 0 1 1 1 0 DNA methylase AviRa PF11599.8 AAZ35460.1 - 0.085 12.3 0.3 0.45 9.9 0.1 1.9 2 0 0 2 2 2 0 RRNA methyltransferase AviRa Methyltransf_16 PF10294.9 AAZ35460.1 - 0.099 12.4 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Glycos_transf_2 PF00535.26 AAZ35461.1 - 6.8e-13 48.8 0.0 9.6e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_4 PF13704.6 AAZ35461.1 - 0.013 16.0 0.3 0.03 14.8 0.1 1.8 1 1 1 2 2 2 0 Glycosyl transferase family 2 Peripla_BP_4 PF13407.6 AAZ35461.1 - 0.098 12.2 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein domain Peripla_BP_4 PF13407.6 AAZ35462.1 - 1.2e-39 136.5 0.5 1.4e-39 136.2 0.5 1.0 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_3 PF13377.6 AAZ35462.1 - 4.6e-11 43.3 0.0 9.1e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Periplasmic binding protein-like domain Sugar_tr PF00083.24 AAZ35463.1 - 5.1e-22 78.4 35.0 2.1e-19 69.7 7.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 AAZ35463.1 - 6.1e-22 78.0 52.8 6.1e-22 78.0 52.8 2.7 1 1 2 3 3 3 2 Major Facilitator Superfamily WCOR413 PF05562.11 AAZ35463.1 - 6.2 6.7 12.2 0.31 11.0 1.1 2.6 3 0 0 3 3 3 0 Cold acclimation protein WCOR413 MFS_1 PF07690.16 AAZ35464.1 - 2.8e-28 98.9 52.6 4.8e-17 61.9 34.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 AAZ35464.1 - 7.8e-06 24.6 4.7 7.8e-06 24.6 4.7 2.6 2 1 0 2 2 2 1 Transmembrane secretion effector Sugar_tr PF00083.24 AAZ35464.1 - 1.5e-05 24.1 28.5 5.2e-05 22.3 11.3 3.5 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 AAZ35464.1 - 0.00049 19.5 31.2 0.00068 19.0 31.2 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 AAZ35464.1 - 0.012 14.5 22.1 0.046 12.6 0.1 3.0 2 1 1 3 3 3 0 MFS_1 like family Spore_YhaL PF14147.6 AAZ35464.1 - 6.6 6.5 6.1 7.4 6.3 0.4 3.1 2 1 1 3 3 3 0 Sporulation protein YhaL Trypan_PARP PF05887.11 AAZ35464.1 - 6.9 6.6 11.3 21 5.1 11.3 1.9 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Acetyltransf_1 PF00583.25 AAZ35465.1 - 4.8e-16 59.0 0.0 6.3e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAZ35465.1 - 3.5e-11 43.4 0.0 5.2e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAZ35465.1 - 9.5e-09 35.3 0.0 1.5e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AAZ35465.1 - 1.2e-06 28.5 0.0 3.5e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 AAZ35465.1 - 6e-06 26.4 0.0 8.4e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAZ35465.1 - 0.00013 21.8 0.0 0.00026 20.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 AAZ35465.1 - 0.0039 17.9 0.0 0.0047 17.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AAZ35465.1 - 0.24 11.5 0.0 0.36 11.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DeoRC PF00455.22 AAZ35466.1 - 2.1e-45 154.5 0.0 2.7e-45 154.2 0.0 1.1 1 0 0 1 1 1 1 DeoR C terminal sensor domain HTH_DeoR PF08220.12 AAZ35466.1 - 2.6e-17 62.3 0.3 4.9e-17 61.4 0.3 1.5 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 AAZ35466.1 - 6.7e-08 32.4 0.2 1.7e-07 31.1 0.2 1.7 1 0 0 1 1 1 1 HTH domain HTH_AsnC-type PF13404.6 AAZ35466.1 - 0.0081 16.0 0.1 0.024 14.5 0.1 1.9 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain Mga PF05043.13 AAZ35466.1 - 0.013 16.0 0.0 0.028 15.0 0.0 1.5 1 0 0 1 1 1 0 Mga helix-turn-helix domain HTH_Crp_2 PF13545.6 AAZ35466.1 - 0.018 15.0 1.0 0.097 12.7 0.1 2.3 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain MarR PF01047.22 AAZ35466.1 - 0.021 14.8 0.3 0.059 13.3 0.1 1.9 2 0 0 2 2 2 0 MarR family HTH_5 PF01022.20 AAZ35466.1 - 0.028 14.3 0.0 0.064 13.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_32 PF13565.6 AAZ35466.1 - 0.054 14.1 0.7 0.17 12.5 0.1 2.0 2 0 0 2 2 2 0 Homeodomain-like domain Put_DNA-bind_N PF06971.13 AAZ35466.1 - 0.066 13.2 0.1 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus GntR PF00392.21 AAZ35466.1 - 0.083 12.6 0.3 0.2 11.3 0.3 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_24 PF13412.6 AAZ35466.1 - 0.1 12.2 0.0 0.29 10.7 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_12 PF08461.10 AAZ35466.1 - 0.12 12.4 1.1 0.25 11.3 0.6 1.9 2 0 0 2 2 2 0 Ribonuclease R winged-helix domain TilS PF09179.11 AAZ35466.1 - 0.6 10.6 4.6 1.4 9.4 0.1 2.7 3 0 0 3 3 2 0 TilS substrate binding domain ADH_N PF08240.12 AAZ35467.1 - 1.4e-25 89.3 0.6 2.3e-25 88.6 0.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AAZ35467.1 - 1.5e-19 70.2 0.0 2.6e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 AAZ35467.1 - 3.9e-07 29.8 0.2 6.1e-06 25.9 0.2 2.1 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 AAZ35467.1 - 2.1e-05 25.6 0.1 9.6e-05 23.4 0.1 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AsnC_trans_reg PF01037.21 AAZ35468.1 - 5.2e-24 84.0 0.0 7.5e-24 83.5 0.0 1.2 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_AsnC-type PF13404.6 AAZ35468.1 - 1.3e-17 63.3 0.9 2.8e-17 62.2 0.9 1.6 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 AAZ35468.1 - 1.3e-17 63.1 0.1 2.3e-17 62.2 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 AAZ35468.1 - 2.1e-07 30.9 0.3 4.3e-07 29.9 0.3 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_11 PF08279.12 AAZ35468.1 - 1.2e-06 28.3 0.1 2e-06 27.6 0.1 1.4 1 0 0 1 1 1 1 HTH domain MarR_2 PF12802.7 AAZ35468.1 - 5.6e-06 26.1 0.2 1e-05 25.3 0.2 1.4 1 0 0 1 1 1 1 MarR family MarR PF01047.22 AAZ35468.1 - 0.0001 22.1 0.1 0.00019 21.3 0.1 1.4 1 0 0 1 1 1 1 MarR family Sigma70_r4_2 PF08281.12 AAZ35468.1 - 0.0019 17.8 0.1 0.0065 16.1 0.1 1.9 1 1 0 1 1 1 1 Sigma-70, region 4 HTH_Crp_2 PF13545.6 AAZ35468.1 - 0.0027 17.6 0.3 0.0082 16.1 0.3 1.8 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_IclR PF09339.10 AAZ35468.1 - 0.0032 17.2 0.8 0.0057 16.4 0.1 1.8 2 0 0 2 2 2 1 IclR helix-turn-helix domain Sigma70_r4 PF04545.16 AAZ35468.1 - 0.0067 15.9 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_5 PF01022.20 AAZ35468.1 - 0.01 15.7 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family LexA_DNA_bind PF01726.16 AAZ35468.1 - 0.021 14.6 0.0 0.051 13.4 0.0 1.7 1 1 0 1 1 1 0 LexA DNA binding domain HTH_27 PF13463.6 AAZ35468.1 - 0.024 15.1 0.1 0.037 14.5 0.1 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain TrmB PF01978.19 AAZ35468.1 - 0.025 14.5 0.0 0.052 13.4 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.20 AAZ35468.1 - 0.027 14.8 0.0 0.068 13.5 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator HTH_DeoR PF08220.12 AAZ35468.1 - 0.03 14.1 0.1 0.063 13.0 0.1 1.5 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_1 PF00126.27 AAZ35468.1 - 0.039 13.9 0.2 0.1 12.6 0.1 1.8 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_Tnp_ISL3 PF13542.6 AAZ35468.1 - 0.1 12.0 0.2 0.24 10.8 0.2 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 EGF_alliinase PF04863.13 AAZ35468.1 - 0.24 11.8 0.1 0.66 10.4 0.0 1.7 2 0 0 2 2 2 0 Alliinase EGF-like domain Glyco_tran_WbsX PF14307.6 AAZ35469.1 - 6.9e-119 397.4 2.7 6.9e-119 397.4 2.7 2.0 2 0 0 2 2 2 1 Glycosyltransferase WbsX RgpF PF05045.12 AAZ35469.1 - 1.8e-46 159.0 0.8 3.1e-46 158.2 0.1 1.8 2 0 0 2 2 2 1 Rhamnan synthesis protein F Glycos_transf_2 PF00535.26 AAZ35469.1 - 1.3e-06 28.4 0.0 4.5e-06 26.6 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferase family 2 TPR_1 PF00515.28 AAZ35469.1 - 0.0062 16.3 4.7 0.013 15.3 0.5 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 AAZ35469.1 - 0.028 14.5 2.2 0.19 11.9 0.3 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 AAZ35469.1 - 0.11 12.7 1.9 1.1 9.7 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF87 PF01935.17 AAZ35469.1 - 0.79 9.8 5.2 0.74 9.9 1.6 2.4 1 1 1 2 2 2 0 Helicase HerA, central domain MttA_Hcf106 PF02416.16 AAZ35470.1 - 5.1e-08 32.1 0.0 6.6e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 mttA/Hcf106 family Thiolase_N PF00108.23 AAZ35471.1 - 3.8e-46 157.6 0.0 6.1e-46 156.9 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 AAZ35471.1 - 4.4e-30 103.9 0.1 7.6e-30 103.1 0.1 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 AAZ35471.1 - 0.002 17.7 0.4 0.0068 16.0 0.4 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ABC_tran PF00005.27 AAZ35472.1 - 8.8e-63 210.9 0.1 4.4e-31 108.2 0.0 2.3 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 AAZ35472.1 - 6.9e-21 74.7 0.0 1e-09 38.2 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AAZ35472.1 - 5.5e-15 56.0 7.8 7.4e-05 22.7 0.1 3.9 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system oligo_HPY PF08352.12 AAZ35472.1 - 1.3e-12 48.1 0.1 5.1e-05 23.7 0.0 2.5 2 0 0 2 2 2 2 Oligopeptide/dipeptide transporter, C-terminal region AAA_16 PF13191.6 AAZ35472.1 - 2.4e-09 37.8 5.4 0.00055 20.4 0.5 2.7 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 AAZ35472.1 - 6.3e-09 36.2 3.3 0.0014 18.9 0.3 3.1 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 AAZ35472.1 - 2.6e-08 33.5 0.6 0.0005 19.8 0.1 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain TniB PF05621.11 AAZ35472.1 - 1.4e-05 24.6 1.6 0.21 11.0 0.1 4.1 4 0 0 4 4 4 1 Bacterial TniB protein AAA_33 PF13671.6 AAZ35472.1 - 1.9e-05 24.9 0.2 0.034 14.3 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_7 PF12775.7 AAZ35472.1 - 3.1e-05 23.6 0.4 0.076 12.5 0.0 2.6 3 0 0 3 3 2 2 P-loop containing dynein motor region DUF87 PF01935.17 AAZ35472.1 - 0.0001 22.5 2.7 0.22 11.6 0.1 2.6 3 0 0 3 3 2 2 Helicase HerA, central domain AAA_30 PF13604.6 AAZ35472.1 - 0.00011 22.0 0.2 0.033 13.9 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 AAZ35472.1 - 0.00016 21.7 1.5 0.27 11.2 0.1 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 AAZ35472.1 - 0.00018 21.4 0.2 0.39 10.6 0.0 2.5 2 0 0 2 2 2 2 NTPase NB-ARC PF00931.22 AAZ35472.1 - 0.00025 20.3 0.1 0.24 10.6 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain NACHT PF05729.12 AAZ35472.1 - 0.00025 21.0 3.6 0.24 11.3 0.3 2.9 3 0 0 3 3 2 2 NACHT domain RsgA_GTPase PF03193.16 AAZ35472.1 - 0.00034 20.5 1.8 0.19 11.6 0.2 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA PF00004.29 AAZ35472.1 - 0.00063 20.2 0.0 2.9 8.3 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 AAZ35472.1 - 0.00072 19.0 0.3 0.42 10.0 0.0 3.2 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 AAZ35472.1 - 0.00081 19.8 0.1 2.2 8.7 0.0 2.4 2 0 0 2 2 2 2 RNA helicase AIG1 PF04548.16 AAZ35472.1 - 0.00087 18.7 0.2 0.18 11.1 0.1 2.3 2 0 0 2 2 2 1 AIG1 family APS_kinase PF01583.20 AAZ35472.1 - 0.002 18.0 0.9 0.49 10.3 0.1 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase ATP-synt_ab PF00006.25 AAZ35472.1 - 0.002 17.8 0.2 0.23 11.1 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain MeaB PF03308.16 AAZ35472.1 - 0.0031 16.5 1.2 0.3 10.0 0.1 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB T2SSE PF00437.20 AAZ35472.1 - 0.0041 16.2 0.3 1.7 7.6 0.1 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.6 AAZ35472.1 - 0.0051 16.4 0.3 11 5.5 0.0 3.6 4 0 0 4 4 3 0 AAA domain SbcCD_C PF13558.6 AAZ35472.1 - 0.0053 17.0 0.1 2.3 8.5 0.0 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ATPase PF06745.13 AAZ35472.1 - 0.0053 16.1 0.4 0.88 8.9 0.1 3.0 3 0 0 3 3 3 1 KaiC TsaE PF02367.17 AAZ35472.1 - 0.0072 16.3 0.4 3.2 7.8 0.1 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 AAZ35472.1 - 0.0074 16.0 4.8 0.82 9.3 0.0 2.8 4 0 0 4 4 2 2 Sigma-54 interaction domain MobB PF03205.14 AAZ35472.1 - 0.0083 16.0 1.0 0.44 10.4 0.1 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.17 AAZ35472.1 - 0.015 15.0 3.5 1 9.1 0.0 3.0 4 0 0 4 4 2 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.18 AAZ35472.1 - 0.016 14.6 0.2 2.5 7.4 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family PRK PF00485.18 AAZ35472.1 - 0.016 15.0 0.1 2.9 7.6 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_23 PF13476.6 AAZ35472.1 - 0.019 15.5 0.1 0.34 11.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 AAZ35472.1 - 0.022 14.0 0.2 0.55 9.4 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.6 AAZ35472.1 - 0.024 15.2 0.0 0.6 10.7 0.0 2.8 3 0 0 3 3 2 0 AAA domain ABC_ATPase PF09818.9 AAZ35472.1 - 0.025 13.4 2.5 6.4 5.5 0.0 3.7 3 2 0 3 3 3 0 Predicted ATPase of the ABC class AAA_19 PF13245.6 AAZ35472.1 - 0.026 14.8 0.5 8.9 6.6 0.0 2.5 2 2 0 2 2 2 0 AAA domain AAA_24 PF13479.6 AAZ35472.1 - 0.029 14.1 0.1 6 6.5 0.1 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 AAZ35472.1 - 0.03 14.4 0.2 0.9 9.6 0.0 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 AAZ35472.1 - 0.044 13.0 0.3 7.9 5.7 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin DUF3987 PF13148.6 AAZ35472.1 - 0.06 12.4 0.3 3 6.8 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) AAA_15 PF13175.6 AAZ35472.1 - 0.073 12.8 0.1 1.3 8.6 0.0 2.3 3 0 0 3 3 2 0 AAA ATPase domain Roc PF08477.13 AAZ35472.1 - 0.14 12.4 0.4 27 5.0 0.2 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 AAZ35472.1 - 0.28 10.9 0.6 5.1 6.8 0.1 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Pox_A32 PF04665.12 AAZ35472.1 - 0.45 9.9 2.3 8.3 5.8 0.0 2.6 3 0 0 3 3 2 0 Poxvirus A32 protein CbiA PF01656.23 AAZ35472.1 - 0.61 10.1 3.1 31 4.6 0.1 3.3 3 1 0 3 3 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain GlnD_UR_UTase PF08335.11 AAZ35473.1 - 1.7e-34 119.0 0.1 4.1e-34 117.8 0.1 1.7 1 0 0 1 1 1 1 GlnD PII-uridylyltransferase HD PF01966.22 AAZ35473.1 - 9.6e-11 42.0 0.1 2.5e-10 40.6 0.1 1.7 1 0 0 1 1 1 1 HD domain ACT PF01842.25 AAZ35473.1 - 8.1e-08 31.9 0.1 3.7e-06 26.6 0.0 2.8 2 0 0 2 2 2 1 ACT domain NTP_transf_2 PF01909.23 AAZ35473.1 - 2.2e-07 31.1 0.0 5.2e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF294 PF03445.13 AAZ35473.1 - 1.5e-05 24.8 0.0 5.9e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 Putative nucleotidyltransferase DUF294 Polbeta PF18765.1 AAZ35473.1 - 0.06 13.4 0.0 0.2 11.8 0.0 1.9 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase GlnE PF03710.15 AAZ35473.1 - 0.062 12.7 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 Glutamate-ammonia ligase adenylyltransferase ACT_6 PF13740.6 AAZ35473.1 - 0.14 12.2 0.0 0.95 9.5 0.0 2.3 3 0 0 3 3 3 0 ACT domain AbrB PF05145.12 AAZ35474.1 - 2.6e-93 312.4 52.4 6.3e-93 311.2 40.4 2.0 1 1 1 2 2 2 2 Transition state regulatory protein AbrB TSP_NTD PF17804.1 AAZ35475.1 - 5.1e-60 203.1 6.4 5.1e-60 203.1 6.4 1.8 2 0 0 2 2 2 1 Tail specific protease N-terminal domain Peptidase_S41 PF03572.18 AAZ35475.1 - 7.4e-52 175.3 0.1 1.4e-51 174.4 0.1 1.5 1 0 0 1 1 1 1 Peptidase family S41 DUF3340 PF11818.8 AAZ35475.1 - 2.2e-40 138.3 5.1 2.2e-40 138.3 5.1 2.5 2 0 0 2 2 2 1 C-terminal domain of tail specific protease (DUF3340) PDZ PF00595.24 AAZ35475.1 - 1.4e-09 38.1 0.8 2.8e-09 37.2 0.8 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 AAZ35475.1 - 0.0048 16.7 0.6 0.021 14.6 0.6 2.0 1 1 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 AAZ35475.1 - 0.031 14.6 0.4 0.088 13.1 0.4 1.9 1 0 0 1 1 1 0 PDZ domain TSNAXIP1_N PF15739.5 AAZ35475.1 - 0.53 10.7 0.0 0.53 10.7 0.0 2.6 3 0 0 3 3 3 0 Translin-associated factor X-interacting N-terminus Amino_oxidase PF01593.24 AAZ35476.1 - 4.1e-24 85.7 0.0 5e-24 85.4 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 AAZ35476.1 - 1.4e-11 44.4 0.0 2.7e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AAZ35476.1 - 6.4e-11 42.4 5.6 1.2e-07 31.7 1.1 2.6 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 AAZ35476.1 - 3.5e-09 37.1 1.5 7.7e-06 26.4 0.4 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AAZ35476.1 - 9.3e-08 31.8 0.1 3.3e-06 26.7 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 AAZ35476.1 - 2e-07 30.5 0.2 3.2e-07 29.8 0.2 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 AAZ35476.1 - 2.6e-06 27.0 0.8 3.9e-06 26.4 0.2 1.6 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 AAZ35476.1 - 4.7e-06 25.9 2.5 1.2e-05 24.7 1.0 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 AAZ35476.1 - 6.2e-06 25.7 0.2 0.00011 21.5 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AAZ35476.1 - 7.3e-06 24.9 0.0 0.00015 20.6 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 AAZ35476.1 - 0.0012 18.0 0.0 0.031 13.3 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein Trp_halogenase PF04820.14 AAZ35476.1 - 0.0014 17.5 0.4 0.0027 16.6 0.4 1.4 1 0 0 1 1 1 1 Tryptophan halogenase GIDA PF01134.22 AAZ35476.1 - 0.0092 15.1 1.3 0.011 14.9 0.4 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_7 PF13241.6 AAZ35476.1 - 0.02 15.3 0.0 0.081 13.4 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 AAZ35476.1 - 0.04 13.2 0.2 0.076 12.3 0.1 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 AAZ35476.1 - 0.057 13.4 0.3 0.9 9.5 0.2 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 AAZ35476.1 - 0.081 12.2 0.3 0.17 11.2 0.1 1.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 AAZ35476.1 - 0.092 13.0 0.4 0.57 10.5 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain GDI PF00996.18 AAZ35476.1 - 0.21 10.1 0.0 0.44 9.0 0.0 1.6 2 0 0 2 2 2 0 GDP dissociation inhibitor UDPG_MGDP_dh_N PF03721.14 AAZ35476.1 - 0.24 11.0 0.1 0.39 10.3 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Abhydrolase_1 PF00561.20 AAZ35477.1 - 2.2e-25 89.8 0.0 6.1e-21 75.2 0.1 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAZ35477.1 - 1e-20 75.3 0.3 1.4e-20 74.8 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAZ35477.1 - 3.5e-17 62.5 0.1 1.7e-16 60.2 0.1 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 AAZ35477.1 - 1.4e-05 25.0 0.0 2.6 7.8 0.0 3.2 3 0 0 3 3 3 3 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.7 AAZ35477.1 - 5.6e-05 23.0 0.0 0.013 15.3 0.1 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 AAZ35477.1 - 0.00066 19.2 0.3 0.66 9.4 0.2 2.5 2 1 0 2 2 2 2 Prolyl oligopeptidase family UPF0227 PF05728.12 AAZ35477.1 - 0.0018 18.2 0.0 0.085 12.8 0.0 2.5 2 1 0 2 2 2 1 Uncharacterised protein family (UPF0227) DLH PF01738.18 AAZ35477.1 - 0.0051 16.4 0.0 0.064 12.8 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family DUF676 PF05057.14 AAZ35477.1 - 0.0092 15.5 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) TrmO PF01980.16 AAZ35478.1 - 3.5e-45 153.0 0.0 4.6e-45 152.7 0.0 1.1 1 0 0 1 1 1 1 tRNA-methyltransferase O TrmO_C PF18389.1 AAZ35478.1 - 1.6e-18 66.5 0.6 2.4e-18 66.0 0.6 1.3 1 0 0 1 1 1 1 TrmO C-terminal domain Radical_SAM PF04055.21 AAZ35479.1 - 7.5e-12 45.9 0.0 4.1e-11 43.5 0.0 1.9 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 AAZ35479.1 - 2.6e-05 24.5 0.0 7.9e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AAZ35479.1 - 4.9e-05 23.5 0.0 8.3e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Aminotran_3 PF00202.21 AAZ35481.1 - 3.7e-126 421.1 0.0 4.2e-126 420.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 AAZ35481.1 - 0.00019 20.7 0.0 0.00029 20.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 AAZ35481.1 - 0.11 11.4 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V HAD_2 PF13419.6 AAZ35482.1 - 1.6e-08 34.8 0.0 2.3e-08 34.4 0.0 1.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAZ35482.1 - 0.007 16.7 0.0 0.43 10.8 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AAZ35482.1 - 0.033 14.2 0.0 0.068 13.2 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like Phage_lysis PF03245.13 AAZ35483.1 - 9.7e-10 38.7 4.1 1.3e-09 38.3 4.1 1.2 1 0 0 1 1 1 1 Bacteriophage Rz lysis protein CHAD PF05235.14 AAZ35484.1 - 8.4e-25 88.1 14.7 1.2e-24 87.6 14.7 1.2 1 0 0 1 1 1 1 CHAD domain GAS PF13851.6 AAZ35484.1 - 0.12 11.7 2.4 0.22 10.8 0.3 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding HSCB_C PF07743.13 AAZ35484.1 - 0.19 12.2 2.1 1.8 9.1 0.1 3.0 2 2 1 3 3 3 0 HSCB C-terminal oligomerisation domain DUF903 PF06004.12 AAZ35485.1 - 8.3e-17 60.8 0.1 1e-16 60.5 0.1 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF903) PEPcase PF00311.17 AAZ35486.1 - 4.9e-274 911.3 0.0 6.2e-274 911.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase PEPcase_2 PF14010.6 AAZ35486.1 - 0.0029 16.2 0.0 0.0047 15.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase HAMP PF00672.25 AAZ35486.1 - 0.0061 16.9 0.1 0.026 14.9 0.1 2.1 1 0 0 1 1 1 1 HAMP domain DUF2868 PF11067.8 AAZ35487.1 - 1.6e-88 297.3 18.5 3e-88 296.4 18.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2868) Peptidase_M56 PF05569.11 AAZ35487.1 - 0.81 8.8 3.8 1.4 8.1 3.8 1.3 1 0 0 1 1 1 0 BlaR1 peptidase M56 ECH_1 PF00378.20 AAZ35488.1 - 6.5e-29 101.0 0.7 7.1e-29 100.9 0.7 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AAZ35488.1 - 8.3e-08 32.1 0.3 9.9e-08 31.8 0.3 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Carbam_trans_C PF16861.5 AAZ35489.1 - 2.5e-60 202.9 0.0 3.9e-60 202.3 0.0 1.3 1 0 0 1 1 1 1 Carbamoyltransferase C-terminus Carbam_trans_N PF02543.15 AAZ35489.1 - 6e-54 184.0 0.0 7.8e-54 183.6 0.0 1.1 1 0 0 1 1 1 1 Carbamoyltransferase N-terminus Transglut_core PF01841.19 AAZ35490.1 - 4.3e-23 81.9 1.4 1.1e-22 80.6 1.3 1.7 2 0 0 2 2 2 1 Transglutaminase-like superfamily Bact_transglu_N PF08379.10 AAZ35490.1 - 1e-22 80.8 0.4 2.2e-22 79.8 0.4 1.6 1 0 0 1 1 1 1 Bacterial transglutaminase-like N-terminal region Transglut_core3 PF13471.6 AAZ35490.1 - 0.0063 16.4 1.0 0.012 15.6 1.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily TraN PF06986.11 AAZ35490.1 - 0.037 13.7 0.0 0.053 13.2 0.0 1.1 1 0 0 1 1 1 0 Type-1V conjugative transfer system mating pair stabilisation Lactamase_B PF00753.27 AAZ35491.1 - 3.3e-05 24.0 2.5 0.015 15.4 2.5 2.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AAZ35491.1 - 0.086 12.4 1.2 1.5 8.3 0.6 2.8 3 1 0 3 3 3 0 Beta-lactamase superfamily domain RMMBL PF07521.12 AAZ35491.1 - 0.097 12.6 0.0 0.65 10.0 0.0 2.1 2 0 0 2 2 2 0 Zn-dependent metallo-hydrolase RNA specificity domain Homoserine_dh PF00742.19 AAZ35492.1 - 4.2e-65 218.9 0.5 9.9e-65 217.7 0.1 1.8 2 0 0 2 2 2 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 AAZ35492.1 - 3.4e-24 85.8 0.4 6.9e-24 84.8 0.4 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ACT PF01842.25 AAZ35492.1 - 1.3e-16 60.0 0.4 9.1e-16 57.3 0.1 2.3 2 0 0 2 2 2 1 ACT domain ACT_4 PF13291.6 AAZ35492.1 - 9.1e-05 23.0 0.1 0.00025 21.6 0.1 1.8 1 0 0 1 1 1 1 ACT domain ACT_7 PF13840.6 AAZ35492.1 - 0.0053 16.5 0.2 0.019 14.8 0.0 2.0 2 0 0 2 2 2 1 ACT domain GFO_IDH_MocA PF01408.22 AAZ35492.1 - 0.0066 17.3 0.3 0.015 16.1 0.3 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold ACT_6 PF13740.6 AAZ35492.1 - 0.0095 15.9 0.1 0.021 14.8 0.1 1.6 1 0 0 1 1 1 1 ACT domain Sacchrp_dh_NADP PF03435.18 AAZ35492.1 - 0.01 16.1 0.4 0.022 15.0 0.4 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DXP_reductoisom PF02670.16 AAZ35492.1 - 0.027 15.2 1.4 0.059 14.1 0.2 2.3 3 1 0 3 3 3 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase DUF2478 PF10649.9 AAZ35492.1 - 0.059 13.0 0.3 7.5 6.1 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2478) FA_synthesis PF02504.15 AAZ35493.1 - 8.9e-101 337.1 0.6 1.1e-100 336.9 0.6 1.0 1 0 0 1 1 1 1 Fatty acid synthesis protein PTA_PTB PF01515.19 AAZ35493.1 - 4e-07 29.7 0.1 7.8e-07 28.7 0.1 1.6 1 1 0 1 1 1 1 Phosphate acetyl/butaryl transferase Catalase PF00199.19 AAZ35494.1 - 7.6e-194 644.1 0.0 9.1e-194 643.9 0.0 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 AAZ35494.1 - 1.7e-23 82.6 0.1 4.3e-23 81.3 0.0 1.7 2 0 0 2 2 2 1 Catalase-related immune-responsive MlaD PF02470.20 AAZ35495.1 - 2.3e-23 82.3 0.3 3.1e-23 81.8 0.3 1.2 1 0 0 1 1 1 1 MlaD protein TetR_C_11 PF16859.5 AAZ35496.1 - 3.3e-19 69.3 4.3 4.4e-19 68.9 1.4 2.3 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 AAZ35496.1 - 5.2e-06 26.2 0.0 8.6e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_IclR PF09339.10 AAZ35496.1 - 0.033 14.0 0.1 0.072 12.9 0.1 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain TetR_C_7 PF14246.6 AAZ35496.1 - 0.039 14.0 0.3 5.1 7.2 0.3 2.8 1 1 0 1 1 1 0 AefR-like transcriptional repressor, C-terminal domain HTH_7 PF02796.15 AAZ35496.1 - 0.066 13.3 0.0 0.21 11.7 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_11 PF08279.12 AAZ35496.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 HTH domain HTH_23 PF13384.6 AAZ35496.1 - 0.12 12.2 0.5 0.53 10.2 0.0 2.1 2 0 0 2 2 2 0 Homeodomain-like domain HTH_38 PF13936.6 AAZ35496.1 - 0.12 12.1 0.1 0.3 10.9 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_28 PF13518.6 AAZ35496.1 - 0.18 12.0 0.9 1.1 9.4 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_3 PF01381.22 AAZ35496.1 - 0.19 11.8 0.1 18 5.5 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix DUF2388 PF09498.10 AAZ35497.1 - 1.3e-29 101.9 3.9 1.6e-29 101.6 3.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2388) LCAT PF02450.15 AAZ35497.1 - 0.2 10.8 0.0 0.24 10.5 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase AurF PF11583.8 AAZ35498.1 - 1.5e-18 67.1 1.2 1.8e-18 66.8 1.2 1.1 1 0 0 1 1 1 1 P-aminobenzoate N-oxygenase AurF Zona_pellucida PF00100.23 AAZ35498.1 - 0.08 12.7 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Zona pellucida-like domain NUDIX PF00293.28 AAZ35499.1 - 1.2e-19 70.7 0.0 1.5e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain Nudix_N_2 PF14803.6 AAZ35499.1 - 6.4e-13 48.4 5.7 1.1e-12 47.7 5.7 1.4 1 0 0 1 1 1 1 Nudix N-terminal Carboxyl_trans PF01039.22 AAZ35500.1 - 1.7e-16 60.0 0.1 2.3e-16 59.5 0.1 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain zf-ACC PF17848.1 AAZ35500.1 - 1.1e-11 44.6 4.3 1.7e-11 43.9 4.3 1.4 1 0 0 1 1 1 1 Acetyl-coA carboxylase zinc finger domain zf-ribbon_3 PF13248.6 AAZ35500.1 - 0.032 13.6 0.4 7.3 6.1 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 AAZ35500.1 - 0.069 13.1 0.2 0.13 12.2 0.2 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Tmemb_55A PF09788.9 AAZ35500.1 - 0.087 11.9 0.2 0.14 11.2 0.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 55A zf-TFIIB PF13453.6 AAZ35500.1 - 0.2 11.0 2.4 2.6 7.5 0.1 2.6 1 1 2 3 3 3 0 Transcription factor zinc-finger zf-C4_Topoisom PF01396.19 AAZ35500.1 - 0.23 11.2 0.9 7.3 6.5 0.1 2.3 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Aldedh PF00171.22 AAZ35501.1 - 1.2e-139 465.8 0.2 1.4e-139 465.6 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family baeRF_family2 PF18844.1 AAZ35501.1 - 0.11 12.5 4.7 0.076 13.1 0.8 2.4 3 0 0 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 2 Oxidored_q2 PF00420.24 AAZ35502.1 - 1.2e-24 86.0 0.9 1.4e-24 85.8 0.9 1.0 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF2749 PF10907.8 AAZ35502.1 - 0.011 15.8 2.7 0.32 11.2 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) BPD_transp_1 PF00528.22 AAZ35503.1 - 1.4e-18 67.3 17.5 1.8e-18 67.0 17.5 1.2 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component FtsX PF02687.21 AAZ35503.1 - 1 9.9 9.7 0.3 11.6 2.9 2.3 2 0 0 2 2 2 0 FtsX-like permease family MFS_1 PF07690.16 AAZ35505.1 - 2.5e-38 131.9 44.2 2.5e-38 131.9 44.2 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 AAZ35505.1 - 8.1e-09 34.8 9.3 8.1e-09 34.8 9.3 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 AAZ35505.1 - 2.3e-07 29.6 26.9 2.7e-07 29.4 26.9 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector Vps5 PF09325.10 AAZ35506.1 - 0.021 14.4 0.5 0.028 14.0 0.5 1.3 1 0 0 1 1 1 0 Vps5 C terminal like DUF4131 PF13567.6 AAZ35506.1 - 0.042 13.5 0.0 0.052 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) JSRP PF15312.6 AAZ35506.1 - 0.16 11.9 0.6 2.9 7.9 0.0 2.2 2 0 0 2 2 2 0 Junctional sarcoplasmic reticulum protein Transposase_mut PF00872.18 AAZ35508.1 - 2e-117 392.3 0.0 2.5e-117 392.0 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ35508.1 - 7.8e-05 23.0 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain Methyltransf_11 PF08241.12 AAZ35509.1 - 1.1e-20 74.1 0.0 2.3e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAZ35509.1 - 1.7e-15 57.5 0.1 4e-15 56.3 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAZ35509.1 - 2.9e-13 49.9 0.0 4.3e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAZ35509.1 - 7.2e-11 42.2 0.0 1e-10 41.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAZ35509.1 - 2.1e-08 34.8 0.0 6e-08 33.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 AAZ35509.1 - 1.1e-07 31.4 0.0 1.7e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 AAZ35509.1 - 0.022 14.6 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_2 PF00891.18 AAZ35509.1 - 0.024 13.9 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Rsm22 PF09243.10 AAZ35509.1 - 0.098 11.9 0.0 0.89 8.8 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial small ribosomal subunit Rsm22 ZapA PF05164.13 AAZ35510.1 - 1.3e-20 73.6 0.1 1.8e-20 73.1 0.1 1.2 1 1 0 1 1 1 1 Cell division protein ZapA DUF2491 PF10679.9 AAZ35511.1 - 1.4e-56 191.0 0.0 1.6e-56 190.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2491) Nudix_N_2 PF14803.6 AAZ35512.1 - 6.3e-18 64.4 4.3 1.3e-17 63.4 4.3 1.6 1 0 0 1 1 1 1 Nudix N-terminal NUDIX PF00293.28 AAZ35512.1 - 1.6e-13 50.8 0.1 1.8e-13 50.6 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain DZR PF12773.7 AAZ35512.1 - 0.0057 16.7 1.6 0.01 15.8 1.6 1.4 1 0 0 1 1 1 1 Double zinc ribbon PknG_rubred PF16919.5 AAZ35512.1 - 0.0064 16.7 0.4 0.01 16.0 0.4 1.3 1 0 0 1 1 1 1 Protein kinase G rubredoxin domain DUF2757 PF10955.8 AAZ35512.1 - 0.057 13.7 0.3 0.21 11.9 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2757) RNA_POL_M_15KD PF02150.16 AAZ35512.1 - 0.063 13.2 1.4 0.14 12.1 1.4 1.6 1 1 0 1 1 1 0 RNA polymerases M/15 Kd subunit zinc_ribbon_2 PF13240.6 AAZ35512.1 - 0.15 11.8 3.4 0.39 10.5 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-NADH-PPase PF09297.11 AAZ35512.1 - 0.15 11.7 6.1 0.23 11.1 0.0 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zf-ribbon_3 PF13248.6 AAZ35512.1 - 0.15 11.5 0.1 0.15 11.5 0.1 1.8 2 0 0 2 2 2 0 zinc-ribbon domain NOB1_Zn_bind PF08772.11 AAZ35512.1 - 0.22 11.7 1.4 0.29 11.3 0.1 1.8 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like GFA PF04828.14 AAZ35512.1 - 0.44 10.9 2.5 19 5.7 0.1 2.5 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-RRN7 PF11781.8 AAZ35512.1 - 3 7.6 9.3 7.6 6.3 4.9 2.5 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 TonB_dep_Rec PF00593.24 AAZ35513.1 - 8.2e-41 141.4 49.6 8.2e-41 141.4 49.6 1.8 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 AAZ35513.1 - 4.8e-14 52.8 0.7 4.8e-14 52.8 0.7 1.9 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain Flg_bbr_C PF06429.13 AAZ35515.1 - 8e-20 70.8 0.5 2.5e-19 69.2 0.5 1.9 1 0 0 1 1 1 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 AAZ35515.1 - 2.8e-08 33.5 3.6 7.5e-08 32.1 3.6 1.7 1 0 0 1 1 1 1 Flagella basal body rod protein PLDc_2 PF13091.6 AAZ35516.1 - 3e-40 137.2 0.0 1.2e-25 90.0 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 AAZ35516.1 - 3.8e-11 42.7 0.0 1.5e-05 25.0 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif Regulator_TrmB PF11495.8 AAZ35516.1 - 0.0021 17.3 0.1 0.076 12.2 0.0 2.3 2 0 0 2 2 2 2 Archaeal transcriptional regulator TrmB YscW PF09619.10 AAZ35517.1 - 1.4e-28 99.4 0.0 1.5e-28 99.3 0.0 1.0 1 0 0 1 1 1 1 Type III secretion system lipoprotein chaperone (YscW) MotA_ExbB PF01618.16 AAZ35518.1 - 3.1e-43 146.6 0.1 4.1e-43 146.2 0.1 1.2 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family DUF2242 PF10001.9 AAZ35519.1 - 1.6e-52 176.8 0.1 2.1e-52 176.4 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2242) HTH_29 PF13551.6 AAZ35520.1 - 0.00023 21.1 0.1 0.00043 20.2 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn helix CENP-B_N PF04218.13 AAZ35520.1 - 0.00045 19.8 0.0 0.0015 18.1 0.0 1.7 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain HTH_11 PF08279.12 AAZ35520.1 - 0.0019 18.1 0.0 0.0038 17.1 0.0 1.5 1 0 0 1 1 1 1 HTH domain HicB_lk_antitox PF15919.5 AAZ35520.1 - 0.0025 17.9 0.0 0.0033 17.5 0.0 1.3 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HTH_23 PF13384.6 AAZ35520.1 - 0.0026 17.5 0.0 0.005 16.6 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.6 AAZ35520.1 - 0.0026 17.5 0.0 0.0063 16.3 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 AAZ35520.1 - 0.005 16.8 0.5 0.03 14.3 0.5 2.1 1 1 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_7 PF02796.15 AAZ35520.1 - 0.0052 16.8 0.0 0.012 15.7 0.0 1.7 2 0 0 2 2 1 1 Helix-turn-helix domain of resolvase Crp PF00325.20 AAZ35520.1 - 0.0071 16.0 0.5 0.013 15.1 0.2 1.6 1 1 0 1 1 1 1 Bacterial regulatory proteins, crp family YdaS_antitoxin PF15943.5 AAZ35520.1 - 0.012 15.4 0.0 0.087 12.7 0.0 2.1 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_28 PF13518.6 AAZ35520.1 - 0.013 15.6 0.0 0.036 14.2 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_26 PF13443.6 AAZ35520.1 - 0.02 15.3 0.0 0.04 14.3 0.0 1.5 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain MarR_2 PF12802.7 AAZ35520.1 - 0.029 14.3 0.2 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 MarR family KORA PF16509.5 AAZ35520.1 - 0.032 14.5 0.0 0.049 13.9 0.0 1.4 1 0 0 1 1 1 0 TrfB plasmid transcriptional repressor SelB-wing_2 PF09106.11 AAZ35520.1 - 0.033 14.4 0.1 0.065 13.4 0.1 1.5 1 0 0 1 1 1 0 Elongation factor SelB, winged helix RepB PF07506.11 AAZ35520.1 - 0.036 14.1 0.1 0.052 13.6 0.1 1.3 1 0 0 1 1 1 0 RepB plasmid partitioning protein HTH_31 PF13560.6 AAZ35520.1 - 0.037 14.4 1.6 0.095 13.1 1.5 2.0 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_3 PF01381.22 AAZ35520.1 - 0.042 13.9 0.0 0.099 12.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix HicB-like_2 PF15970.5 AAZ35520.1 - 0.043 14.0 0.0 0.06 13.5 0.0 1.2 1 0 0 1 1 1 0 HicB_like antitoxin of bacterial toxin-antitoxin system HTH_20 PF12840.7 AAZ35520.1 - 0.079 13.0 0.8 0.14 12.2 0.1 1.8 2 1 0 2 2 2 0 Helix-turn-helix domain SMC_Nse1 PF07574.13 AAZ35521.1 - 0.099 12.5 0.0 0.14 12.1 0.0 1.2 1 1 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex Trypsin_2 PF13365.6 AAZ35522.1 - 1.3e-23 84.6 1.0 3.6e-23 83.1 0.9 1.8 2 0 0 2 2 2 1 Trypsin-like peptidase domain TerD PF02342.18 AAZ35522.1 - 1.7e-08 34.2 0.0 2.7e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 TerD domain Trypsin PF00089.26 AAZ35522.1 - 4.4e-06 26.7 0.6 2.8e-05 24.0 0.1 2.5 2 1 0 2 2 2 1 Trypsin Peptidase_S29 PF02907.15 AAZ35522.1 - 0.054 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease Peptidase_S55 PF05580.12 AAZ35522.1 - 0.16 11.9 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 SpoIVB peptidase S55 Hemerythrin PF01814.23 AAZ35523.1 - 9.3e-14 52.2 10.9 1.2e-13 51.8 10.9 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain G6PD_N PF00479.22 AAZ35523.1 - 0.014 16.1 1.7 1.9 9.1 0.1 2.1 1 1 1 2 2 2 0 Glucose-6-phosphate dehydrogenase, NAD binding domain Mrr_cat_2 PF13156.6 AAZ35523.1 - 0.056 13.3 0.2 0.37 10.7 0.1 2.0 1 1 1 2 2 2 0 Restriction endonuclease MotA_ExbB PF01618.16 AAZ35524.1 - 1.9e-32 111.7 1.5 1.9e-32 111.7 1.5 1.7 2 0 0 2 2 2 1 MotA/TolQ/ExbB proton channel family Ribonuc_L-PSP PF01042.21 AAZ35525.1 - 4.9e-23 81.4 0.0 5.8e-23 81.2 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP GGDEF PF00990.21 AAZ35526.1 - 1.1e-44 152.1 0.0 1.3e-44 151.8 0.0 1.1 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain MASE2 PF05230.11 AAZ35526.1 - 2e-14 53.4 0.3 6.3e-13 48.6 0.0 2.4 2 0 0 2 2 2 1 MASE2 domain GGDEF_2 PF17853.1 AAZ35526.1 - 6.5e-05 23.2 0.0 0.0001 22.5 0.0 1.3 1 0 0 1 1 1 1 GGDEF-like domain DUF2085 PF09858.9 AAZ35526.1 - 0.14 12.7 1.5 0.18 12.3 0.4 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2085) PAP2 PF01569.21 AAZ35527.1 - 1.9e-09 37.4 8.5 3.5e-09 36.6 8.5 1.4 1 0 0 1 1 1 1 PAP2 superfamily Peptidase_U4 PF03419.13 AAZ35527.1 - 2.6 7.3 4.4 1.2 8.3 1.5 1.8 2 0 0 2 2 2 0 Sporulation factor SpoIIGA Response_reg PF00072.24 AAZ35528.1 - 4.4e-27 94.5 0.0 6.3e-27 94.0 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAZ35528.1 - 9.6e-16 57.6 0.6 1.8e-15 56.8 0.1 1.7 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal FleQ PF06490.11 AAZ35528.1 - 3.1e-05 24.3 0.0 4.5e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Flagellar regulatory protein FleQ SH3_16 PF18348.1 AAZ35528.1 - 0.067 13.0 0.1 2.7 7.9 0.0 2.7 2 0 0 2 2 2 0 Bacterial dipeptidyl-peptidase Sh3 domain OKR_DC_1_N PF03709.15 AAZ35528.1 - 0.1 12.9 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain CN_hydrolase PF00795.22 AAZ35529.1 - 1.9e-49 168.4 0.1 2.1e-49 168.2 0.1 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF3875 PF12991.7 AAZ35529.1 - 0.12 12.3 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3875) Amidase PF01425.21 AAZ35530.1 - 1.6e-84 284.5 0.0 5e-80 269.7 0.0 2.0 1 1 1 2 2 2 2 Amidase VbhA PF18495.1 AAZ35530.1 - 0.14 12.1 0.0 0.39 10.6 0.0 1.8 1 0 0 1 1 1 0 Antitoxin VbhA Glycos_transf_1 PF00534.20 AAZ35531.1 - 1.9e-31 108.9 0.0 2.9e-31 108.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAZ35531.1 - 1.8e-17 64.0 0.1 4.5e-17 62.7 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAZ35531.1 - 4.3e-11 43.1 0.3 1.6e-10 41.3 0.1 2.1 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 AAZ35531.1 - 3.4e-06 27.4 0.0 7.5e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 AAZ35531.1 - 4.4e-06 27.2 1.7 0.00032 21.2 0.0 3.5 2 2 1 3 3 3 1 Glycosyl transferase 4-like domain Glyco_transf_20 PF00982.21 AAZ35531.1 - 0.0046 15.7 0.0 0.013 14.2 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase family 20 FecR PF04773.13 AAZ35532.1 - 8.8e-14 51.9 0.3 1.6e-13 51.1 0.3 1.4 1 0 0 1 1 1 1 FecR protein DUF4880 PF16220.5 AAZ35532.1 - 9.8e-12 44.6 12.1 2.5e-11 43.3 12.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4880) YqjK PF13997.6 AAZ35532.1 - 0.00057 20.1 3.3 0.0014 18.8 1.7 2.4 2 0 0 2 2 2 1 YqjK-like protein DUF4974 PF16344.5 AAZ35532.1 - 0.033 14.2 0.0 0.091 12.8 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4974) DUF3389 PF11869.8 AAZ35532.1 - 0.044 14.0 0.0 0.15 12.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3389) RsdA_SigD_bd PF16751.5 AAZ35532.1 - 0.37 11.1 4.9 2.5 8.4 0.1 3.7 4 0 0 4 4 4 0 Anti-sigma-D factor RsdA to sigma factor binding region MCPsignal PF00015.21 AAZ35533.1 - 3.8e-42 144.0 30.6 6.8e-42 143.2 18.1 4.1 3 1 2 5 5 5 3 Methyl-accepting chemotaxis protein (MCP) signalling domain 4HB_MCP_1 PF12729.7 AAZ35533.1 - 6e-15 55.2 3.8 6e-15 55.2 3.8 3.6 4 2 1 5 5 5 1 Four helix bundle sensory module for signal transduction TarH PF02203.15 AAZ35533.1 - 5.7e-10 39.4 4.9 5.7e-10 39.4 4.9 4.6 4 2 1 5 5 5 1 Tar ligand binding domain homologue DUF3796 PF12676.7 AAZ35533.1 - 0.039 14.4 0.8 1.2 9.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3796) BacA PF02673.18 AAZ35533.1 - 0.05 13.3 2.2 0.28 10.9 0.3 2.2 2 0 0 2 2 2 0 Bacitracin resistance protein BacA HAMP PF00672.25 AAZ35533.1 - 0.71 10.3 10.4 3.3 8.2 0.7 4.7 4 1 0 4 4 4 0 HAMP domain DUF3829 PF12889.7 AAZ35533.1 - 2.8 7.4 11.4 6.8 6.1 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3829) Orf78 PF06024.12 AAZ35533.1 - 5 7.5 5.8 25 5.2 0.0 3.4 3 1 0 3 3 3 0 Orf78 (ac78) IU_nuc_hydro PF01156.19 AAZ35534.1 - 1.3e-44 153.0 0.3 1.6e-44 152.7 0.3 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Glyco_hydro_19 PF00182.19 AAZ35535.1 - 6.5e-11 42.6 0.0 1.1e-10 41.9 0.0 1.3 1 0 0 1 1 1 1 Chitinase class I T2SSE PF00437.20 AAZ35536.1 - 1.9e-86 289.5 0.9 1.9e-86 289.5 0.9 1.4 2 0 0 2 2 2 1 Type II/IV secretion system protein T2SSE_N PF05157.15 AAZ35536.1 - 2.3e-12 47.2 0.0 6.4e-12 45.7 0.0 1.8 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein E, N-terminal domain AAA_22 PF13401.6 AAZ35536.1 - 0.00016 22.0 0.0 0.0005 20.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAZ35536.1 - 0.00019 21.8 1.5 0.00056 20.3 0.0 2.6 3 1 0 3 3 3 1 AAA ATPase domain Rad17 PF03215.15 AAZ35536.1 - 0.0042 17.0 0.0 0.007 16.3 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_23 PF13476.6 AAZ35536.1 - 0.005 17.4 0.0 0.01 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 AAZ35536.1 - 0.0073 15.8 0.0 0.029 13.9 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region ATPase_2 PF01637.18 AAZ35536.1 - 0.0074 16.2 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_29 PF13555.6 AAZ35536.1 - 0.0081 15.9 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_19 PF13245.6 AAZ35536.1 - 0.0085 16.4 0.4 0.026 14.9 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 AAZ35536.1 - 0.012 15.3 0.1 0.057 13.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 AAZ35536.1 - 0.018 15.0 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 AAZ35536.1 - 0.035 13.9 0.0 0.054 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AAZ35536.1 - 0.037 14.6 0.0 0.11 13.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain cobW PF02492.19 AAZ35536.1 - 0.04 13.5 0.1 0.066 12.8 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RecA PF00154.21 AAZ35536.1 - 0.067 12.6 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein ABC_tran PF00005.27 AAZ35536.1 - 0.08 13.5 0.0 0.19 12.2 0.0 1.6 1 0 0 1 1 1 0 ABC transporter ResIII PF04851.15 AAZ35536.1 - 0.085 12.9 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NTPase_1 PF03266.15 AAZ35536.1 - 0.1 12.5 0.5 0.47 10.3 0.2 2.0 2 0 0 2 2 2 0 NTPase CTP_transf_3 PF02348.19 AAZ35537.1 - 1.3e-57 195.2 0.0 1.6e-57 194.9 0.0 1.0 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 AAZ35537.1 - 1.3e-09 38.6 1.0 1.6e-09 38.3 1.0 1.3 1 1 0 1 1 1 1 MobA-like NTP transferase domain DUF2064 PF09837.9 AAZ35537.1 - 0.047 13.5 0.4 0.077 12.8 0.4 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2064) Glyco_trans_1_4 PF13692.6 AAZ35538.1 - 5.7e-22 78.6 0.0 9.2e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 AAZ35538.1 - 4.8e-18 66.1 1.7 4.8e-18 66.1 1.7 2.1 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 AAZ35538.1 - 6.2e-14 52.3 0.4 1.3e-13 51.3 0.2 1.6 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 AAZ35538.1 - 3.7e-11 43.3 0.0 1.2e-10 41.6 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AAZ35538.1 - 1.4e-06 28.0 0.0 2.1e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 FA_desaturase PF00487.24 AAZ35539.1 - 2.4e-37 129.2 8.1 3.5e-37 128.6 8.1 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF2270 PF10028.9 AAZ35539.1 - 0.21 11.1 3.0 1.6 8.3 1.4 2.3 1 1 0 2 2 2 0 Predicted integral membrane protein (DUF2270) DcrB PF08786.11 AAZ35540.1 - 0.025 14.7 0.0 0.037 14.1 0.0 1.3 1 0 0 1 1 1 0 DcrB Asp_Arg_Hydrox PF05118.15 AAZ35541.1 - 1.4e-47 161.5 0.0 1.9e-47 161.0 0.0 1.2 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Cupin_2 PF07883.11 AAZ35541.1 - 0.14 11.9 0.0 0.43 10.3 0.0 1.7 2 0 0 2 2 2 0 Cupin domain TonB_dep_Rec PF00593.24 AAZ35542.1 - 2.3e-43 149.8 32.4 2.3e-43 149.8 32.4 2.0 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 AAZ35542.1 - 3.7e-20 72.5 2.9 8.4e-20 71.4 2.9 1.7 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain Ribosomal_L30 PF00327.20 AAZ35543.1 - 3.5e-16 58.8 0.1 3.9e-16 58.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Sigma54_activat PF00158.26 AAZ35544.1 - 2e-70 235.8 0.0 3.2e-70 235.2 0.0 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AAZ35544.1 - 1.5e-20 73.7 0.0 3.4e-20 72.6 0.0 1.6 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 AAZ35544.1 - 7.4e-08 32.5 0.0 1.6e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 AAZ35544.1 - 0.00056 19.4 0.1 0.56 9.6 0.0 2.6 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA PF00004.29 AAZ35544.1 - 0.00061 20.2 0.0 0.0012 19.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) HTH_8 PF02954.19 AAZ35544.1 - 0.0017 18.1 0.2 0.0045 16.7 0.0 1.8 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family AAA_16 PF13191.6 AAZ35544.1 - 0.0038 17.6 0.8 0.013 15.9 0.8 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 AAZ35544.1 - 0.0048 17.0 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 AAZ35544.1 - 0.01 16.1 0.1 0.099 12.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain MCM PF00493.23 AAZ35544.1 - 0.016 14.3 0.0 0.037 13.1 0.0 1.6 1 0 0 1 1 1 0 MCM P-loop domain ATPase PF06745.13 AAZ35544.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_3 PF07726.11 AAZ35544.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SSK PF03934.13 AAZ35545.1 - 6.5e-10 38.9 8.3 0.00018 21.0 4.7 2.1 1 1 1 2 2 2 2 Type II secretion system (T2SS), protein K Cache_3-Cache_2 PF17201.4 AAZ35546.1 - 1.3e-78 264.3 7.6 1.6e-78 264.0 0.0 3.1 2 1 2 4 4 4 1 Cache 3/Cache 2 fusion domain MCPsignal PF00015.21 AAZ35546.1 - 1.1e-42 145.8 33.7 1.4e-41 142.2 24.6 2.8 1 1 2 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain sCache_3_3 PF17202.4 AAZ35546.1 - 4.7e-28 97.7 2.1 7.3e-28 97.1 0.3 2.3 2 0 0 2 2 2 1 Single cache domain 3 HAMP PF00672.25 AAZ35546.1 - 1.7e-15 57.1 2.2 1e-14 54.6 0.0 3.6 4 0 0 4 4 4 1 HAMP domain sCache_3_2 PF17203.4 AAZ35546.1 - 7.2e-09 35.9 0.1 7.2e-09 35.9 0.1 2.9 2 1 0 2 2 2 1 Single cache domain 3 dCache_1 PF02743.18 AAZ35546.1 - 3.4e-07 30.3 0.0 3.4e-07 30.3 0.0 3.3 2 1 0 2 2 1 1 Cache domain PAS_4 PF08448.10 AAZ35546.1 - 0.0069 16.6 0.0 0.026 14.8 0.0 2.0 2 0 0 2 2 2 1 PAS fold MHYT PF03707.16 AAZ35546.1 - 1.2 9.3 5.1 7.8 6.8 0.2 2.9 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat GAT PF03127.14 AAZ35546.1 - 6.1 7.2 8.0 4.9 7.5 0.1 3.9 5 0 0 5 5 5 0 GAT domain TPPK_C PF12555.8 AAZ35546.1 - 6.9 6.8 7.4 20 5.3 1.1 3.0 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal Folliculin PF11704.8 AAZ35546.1 - 9.7 6.0 15.5 1.2 9.0 3.0 3.1 2 2 1 3 3 3 0 Vesicle coat protein involved in Golgi to plasma membrane transport Aconitase PF00330.20 AAZ35548.1 - 8.3e-158 526.2 0.0 9.4e-158 526.0 0.0 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) BPD_transp_2 PF02653.16 AAZ35549.1 - 2.4e-41 141.7 44.0 2.4e-41 141.7 44.0 2.3 2 1 0 2 2 2 1 Branched-chain amino acid transport system / permease component SBP_bac_5 PF00496.22 AAZ35550.1 - 1.2e-90 304.2 1.2 1.4e-90 304.0 1.2 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle ThiF PF00899.21 AAZ35551.1 - 1.6e-61 207.8 0.1 2e-61 207.5 0.1 1.0 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 AAZ35551.1 - 1e-05 25.8 1.0 5.3e-05 23.5 1.0 1.9 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 AAZ35551.1 - 0.049 13.0 0.2 0.91 8.9 0.1 2.2 1 1 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CoaE PF01121.20 AAZ35552.1 - 1.1e-64 217.5 0.0 1.3e-64 217.2 0.0 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_28 PF13521.6 AAZ35552.1 - 0.13 12.5 0.1 1.5 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 AAZ35553.1 - 5.2e-28 98.3 0.0 6.9e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAZ35553.1 - 0.00015 21.7 0.3 0.27 11.0 0.1 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 AAZ35553.1 - 0.0085 16.0 0.2 0.024 14.5 0.1 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 AAZ35553.1 - 0.01 16.2 1.3 0.034 14.5 1.3 1.8 1 1 0 1 1 1 0 AAA ATPase domain SbcCD_C PF13558.6 AAZ35553.1 - 0.01 16.0 0.4 0.1 12.9 0.4 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 AAZ35553.1 - 0.02 15.1 0.2 0.27 11.5 0.1 2.4 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 AAZ35553.1 - 0.026 14.9 0.0 0.19 12.1 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 AAZ35553.1 - 0.036 14.1 0.0 0.31 11.1 0.0 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase SMC_N PF02463.19 AAZ35553.1 - 0.036 13.5 0.3 4 6.8 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AAZ35553.1 - 0.039 14.2 0.0 0.13 12.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 AAZ35553.1 - 0.044 12.8 0.0 0.063 12.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 AAZ35553.1 - 0.13 12.0 0.0 0.34 10.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 AAZ35553.1 - 0.23 11.4 0.0 0.74 9.7 0.0 1.8 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea Fer4 PF00037.27 AAZ35554.1 - 3.2e-08 33.1 21.5 7.2e-06 25.6 5.6 3.2 3 0 0 3 3 3 3 4Fe-4S binding domain Fer4_7 PF12838.7 AAZ35554.1 - 7.9e-06 26.4 14.8 6.7e-05 23.4 15.4 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAZ35554.1 - 5.1e-05 23.1 14.0 0.0072 16.4 2.3 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 AAZ35554.1 - 0.00011 22.3 14.4 0.00018 21.6 14.4 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAZ35554.1 - 0.00012 22.2 24.4 0.00091 19.3 13.5 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAZ35554.1 - 0.00013 22.8 13.5 0.045 14.7 6.8 2.3 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain GF_recep_IV PF14843.6 AAZ35554.1 - 0.0046 16.8 8.9 0.0052 16.6 8.9 1.1 1 0 0 1 1 1 1 Growth factor receptor domain IV Fer4_21 PF14697.6 AAZ35554.1 - 0.0061 16.7 19.0 0.015 15.4 19.0 1.8 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_4 PF12800.7 AAZ35554.1 - 0.019 15.4 2.9 0.019 15.4 2.9 2.8 2 1 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.7 AAZ35554.1 - 0.032 14.3 18.7 0.12 12.5 4.8 2.5 2 1 0 2 2 2 0 4Fe-4S binding domain Fer4_3 PF12798.7 AAZ35554.1 - 0.49 11.5 20.1 1.6 9.8 7.8 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_8 PF13183.6 AAZ35554.1 - 1.2 9.7 15.9 0.57 10.7 3.5 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAZ35554.1 - 1.9 9.1 17.5 0.16 12.5 4.6 2.7 1 1 2 3 3 3 0 4Fe-4S dicluster domain DUF3299 PF11736.8 AAZ35555.1 - 2.8e-48 163.4 0.2 3.3e-48 163.2 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3299) Ribosomal_L33 PF00471.20 AAZ35556.1 - 1.3e-17 63.9 0.0 1.5e-17 63.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L33 AAA_2 PF07724.14 AAZ35557.1 - 1.4e-51 175.0 0.0 5e-49 166.7 0.0 2.9 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 AAZ35557.1 - 3.5e-28 97.6 0.7 9e-28 96.3 0.7 1.7 1 0 0 1 1 1 1 AAA lid domain AAA PF00004.29 AAZ35557.1 - 1.3e-27 96.8 0.0 2.8e-12 47.2 0.0 3.1 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 AAZ35557.1 - 3.8e-25 87.7 0.2 4.3e-24 84.4 0.1 2.7 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 AAZ35557.1 - 6.4e-20 71.6 0.0 4.6e-14 52.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 AAZ35557.1 - 2e-15 56.6 3.6 4.3e-15 55.6 1.0 3.0 3 0 0 3 3 2 1 Clp amino terminal domain, pathogenicity island component AAA_16 PF13191.6 AAZ35557.1 - 5.7e-14 52.9 6.3 1.1e-07 32.5 0.3 4.8 5 1 0 5 5 3 2 AAA ATPase domain AAA_22 PF13401.6 AAZ35557.1 - 9.6e-12 45.3 0.6 0.00027 21.2 0.1 4.2 2 2 1 3 3 3 2 AAA domain Sigma54_activat PF00158.26 AAZ35557.1 - 6.9e-11 42.1 0.1 2.2e-06 27.5 0.0 2.6 2 1 0 2 2 2 2 Sigma-54 interaction domain TniB PF05621.11 AAZ35557.1 - 6.4e-08 32.2 0.0 4.8e-05 22.9 0.0 3.5 2 1 0 2 2 2 1 Bacterial TniB protein RuvB_N PF05496.12 AAZ35557.1 - 1.4e-07 31.3 2.2 0.026 14.3 0.1 4.4 2 2 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 AAZ35557.1 - 7.7e-07 29.7 0.0 0.019 15.5 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_14 PF13173.6 AAZ35557.1 - 8.4e-07 29.1 0.0 0.044 13.8 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_7 PF12775.7 AAZ35557.1 - 1.4e-06 28.0 0.0 0.071 12.6 0.0 2.9 2 1 0 2 2 2 2 P-loop containing dynein motor region Mg_chelatase PF01078.21 AAZ35557.1 - 2.2e-06 27.2 0.2 0.45 9.9 0.0 3.5 2 2 1 3 3 3 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 AAZ35557.1 - 3.4e-06 26.9 0.0 0.033 13.9 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein TsaE PF02367.17 AAZ35557.1 - 4.1e-06 26.8 0.0 0.082 12.9 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 AAZ35557.1 - 7.1e-06 25.9 0.1 0.00033 20.5 0.0 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 AAZ35557.1 - 1.4e-05 25.3 0.0 0.0039 17.4 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_6 PF12774.7 AAZ35557.1 - 1.5e-05 24.1 0.0 7e-05 21.9 0.0 2.0 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region RNA_helicase PF00910.22 AAZ35557.1 - 5.6e-05 23.5 0.0 0.42 11.0 0.0 2.9 3 0 0 3 3 3 2 RNA helicase TIP49 PF06068.13 AAZ35557.1 - 7.2e-05 22.2 0.0 0.019 14.2 0.0 2.6 2 0 0 2 2 2 1 TIP49 P-loop domain ATPase_2 PF01637.18 AAZ35557.1 - 0.00017 21.6 0.0 0.27 11.1 0.0 3.5 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea NACHT PF05729.12 AAZ35557.1 - 0.00019 21.4 0.0 0.06 13.3 0.0 3.0 3 0 0 3 3 2 1 NACHT domain Zeta_toxin PF06414.12 AAZ35557.1 - 0.00054 19.3 0.0 0.25 10.6 0.0 2.8 2 0 0 2 2 2 1 Zeta toxin ResIII PF04851.15 AAZ35557.1 - 0.0015 18.5 0.0 5.1 7.1 0.0 3.4 2 1 0 3 3 3 0 Type III restriction enzyme, res subunit DNA_pol3_delta2 PF13177.6 AAZ35557.1 - 0.0018 18.1 0.0 0.95 9.2 0.0 3.4 3 0 0 3 3 3 1 DNA polymerase III, delta subunit SRP54 PF00448.22 AAZ35557.1 - 0.0021 17.7 0.4 3.1 7.4 0.0 3.1 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain Rad17 PF03215.15 AAZ35557.1 - 0.0022 17.9 0.0 0.5 10.3 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 AAZ35557.1 - 0.0064 16.4 0.0 1.3 8.9 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase Torsin PF06309.11 AAZ35557.1 - 0.0099 16.0 0.0 0.06 13.4 0.0 2.1 2 0 0 2 2 2 1 Torsin IPT PF01745.16 AAZ35557.1 - 0.015 14.7 0.0 0.15 11.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase AAA_30 PF13604.6 AAZ35557.1 - 0.035 13.8 1.2 2.1 8.1 0.0 3.2 3 1 1 4 4 3 0 AAA domain CobT_C PF11775.8 AAZ35557.1 - 0.039 13.6 0.0 0.074 12.7 0.0 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain NB-ARC PF00931.22 AAZ35557.1 - 0.04 13.1 0.0 0.55 9.4 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.15 AAZ35557.1 - 0.047 13.6 0.2 28 4.6 0.0 3.9 5 0 0 5 5 3 0 NTPase AAA_28 PF13521.6 AAZ35557.1 - 0.054 13.7 0.0 2.8 8.1 0.0 3.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 AAZ35557.1 - 0.054 13.1 0.3 8.8 5.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain Hpr_kinase_C PF07475.12 AAZ35557.1 - 0.056 13.0 0.0 7.9 6.0 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain T2SSE PF00437.20 AAZ35557.1 - 0.079 12.0 0.0 4.2 6.4 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_24 PF13479.6 AAZ35557.1 - 0.084 12.6 0.0 15 5.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain SKI PF01202.22 AAZ35557.1 - 0.097 12.8 0.4 0.79 9.8 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase AAA_29 PF13555.6 AAZ35557.1 - 0.12 12.2 0.0 15 5.4 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Phage_CRI PF05144.14 AAZ35557.1 - 0.12 11.7 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Phage replication protein CRI Roc PF08477.13 AAZ35557.1 - 0.12 12.6 0.0 2.3 8.4 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PhoH PF02562.16 AAZ35557.1 - 0.14 11.6 0.3 7.2 6.0 0.0 3.0 3 0 0 3 3 3 0 PhoH-like protein FliG_N PF14842.6 AAZ35557.1 - 0.27 11.8 2.5 3.9 8.1 0.0 3.7 4 1 1 5 5 3 0 FliG N-terminal domain AraC_binding PF02311.19 AAZ35558.1 - 7.8e-25 87.4 3.7 1.2e-24 86.8 3.7 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain HTH_18 PF12833.7 AAZ35558.1 - 3e-20 72.3 1.0 1.4e-19 70.1 0.5 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAZ35558.1 - 9.7e-13 47.9 0.0 1.6e-05 24.9 0.0 2.6 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family AraC_binding_2 PF14525.6 AAZ35558.1 - 0.002 17.8 1.3 0.002 17.8 1.3 1.8 2 0 0 2 2 2 1 AraC-binding-like domain ROS_MUCR PF05443.11 AAZ35558.1 - 0.12 12.4 0.0 18 5.4 0.0 2.5 2 0 0 2 2 2 0 ROS/MUCR transcriptional regulator protein Peptidase_M24 PF00557.24 AAZ35558.1 - 0.13 11.9 0.2 0.24 11.1 0.1 1.5 1 1 1 2 2 2 0 Metallopeptidase family M24 Phage_lysis PF03245.13 AAZ35559.1 - 5.6e-25 87.9 5.2 7.4e-25 87.5 5.2 1.1 1 0 0 1 1 1 1 Bacteriophage Rz lysis protein NYD-SP28_assoc PF14775.6 AAZ35559.1 - 0.014 15.5 1.4 0.023 14.8 0.0 2.0 3 0 0 3 3 3 0 Sperm tail C-terminal domain PPDK_N PF01326.19 AAZ35560.1 - 5e-34 118.0 0.0 1.1e-26 93.9 0.0 3.4 4 0 0 4 4 4 2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 AAZ35560.1 - 3.8e-05 23.3 0.0 0.00071 19.3 0.0 2.9 3 0 0 3 3 3 1 PEP-utilising enzyme, mobile domain SBP_bac_8 PF13416.6 AAZ35561.1 - 4.8e-22 79.1 0.0 6.2e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AAZ35561.1 - 3.5e-11 43.6 0.0 4.9e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein OEP PF02321.18 AAZ35562.1 - 1.5e-46 158.6 31.8 4.7e-27 95.0 9.7 2.0 2 0 0 2 2 2 2 Outer membrane efflux protein CRF PF00473.17 AAZ35562.1 - 0.29 11.2 9.8 14 5.8 0.1 2.8 2 0 0 2 2 2 0 Corticotropin-releasing factor family PDH_E1_M PF17831.1 AAZ35563.1 - 1.4e-120 401.1 0.1 2.1e-120 400.5 0.1 1.2 1 0 0 1 1 1 1 Pyruvate dehydrogenase E1 component middle domain Transketolase_N PF00456.21 AAZ35563.1 - 3e-12 46.2 0.0 3.4e-06 26.2 0.0 2.2 2 0 0 2 2 2 2 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.20 AAZ35563.1 - 0.00048 20.0 0.0 0.0048 16.8 0.0 2.3 2 0 0 2 2 2 1 Transketolase, C-terminal domain Stevor PF17410.2 AAZ35563.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame CbiD PF01888.17 AAZ35564.1 - 5e-88 294.7 0.2 7e-88 294.2 0.2 1.2 1 0 0 1 1 1 1 CbiD DUF1989 PF09347.10 AAZ35566.1 - 2.9e-66 222.2 0.0 3.3e-66 222.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Gp_dh_C PF02800.20 AAZ35567.1 - 2.4e-49 167.0 0.0 3.2e-49 166.6 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 AAZ35567.1 - 3.6e-34 117.1 0.0 8.8e-34 115.9 0.0 1.7 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain NAD_binding_3 PF03447.16 AAZ35567.1 - 0.0017 19.0 0.0 0.0096 16.6 0.0 2.1 1 1 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF1375 PF07119.12 AAZ35569.1 - 2.7e-12 46.9 0.0 5e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1375) ADH_zinc_N PF00107.26 AAZ35570.1 - 5.6e-27 94.3 0.3 8.4e-27 93.7 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AAZ35570.1 - 1.8e-17 64.6 0.1 5.5e-17 63.1 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 AAZ35570.1 - 7e-07 28.9 0.2 8.5e-07 28.7 0.2 1.1 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 AAZ35570.1 - 0.0014 17.9 0.2 0.0027 17.0 0.1 1.5 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain SIS_2 PF13580.6 AAZ35570.1 - 0.061 13.3 2.0 0.061 13.3 0.1 1.8 2 0 0 2 2 2 0 SIS domain Pribosyltran PF00156.27 AAZ35570.1 - 0.064 12.8 0.2 2.4 7.7 0.0 2.2 2 0 0 2 2 2 0 Phosphoribosyl transferase domain Sacchrp_dh_NADP PF03435.18 AAZ35570.1 - 0.11 12.8 0.1 0.18 12.1 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Transposase_mut PF00872.18 AAZ35571.1 - 5.8e-117 390.8 0.0 7.3e-117 390.4 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ35571.1 - 7.8e-05 23.0 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain DUF4844 PF16133.5 AAZ35571.1 - 0.23 12.0 0.0 0.55 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) FecCD PF01032.18 AAZ35572.1 - 8.5e-84 281.2 42.3 1.1e-83 280.8 42.3 1.1 1 0 0 1 1 1 1 FecCD transport family UTRA PF07702.13 AAZ35573.1 - 6.2e-27 94.2 0.2 8.8e-27 93.7 0.2 1.2 1 0 0 1 1 1 1 UTRA domain GntR PF00392.21 AAZ35573.1 - 1.1e-16 60.2 0.2 2.4e-16 59.1 0.1 1.7 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family MarR PF01047.22 AAZ35573.1 - 0.0046 16.9 0.0 0.0091 15.9 0.0 1.4 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.20 AAZ35573.1 - 0.011 16.1 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator MarR_2 PF12802.7 AAZ35573.1 - 0.035 14.0 0.1 0.12 12.2 0.1 1.9 1 0 0 1 1 1 0 MarR family HTH_11 PF08279.12 AAZ35573.1 - 0.075 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 HTH domain HTH_DeoR PF08220.12 AAZ35573.1 - 0.076 12.8 0.2 0.14 11.9 0.2 1.4 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_36 PF13730.6 AAZ35573.1 - 0.19 11.7 0.0 0.4 10.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HlyD_D23 PF16576.5 AAZ35574.1 - 5.5e-39 133.6 0.8 1.1e-38 132.7 0.8 1.5 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AAZ35574.1 - 3e-16 60.0 6.4 3.5e-12 47.0 0.0 3.8 3 1 0 3 3 3 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AAZ35574.1 - 8.4e-08 31.9 2.7 2e-07 30.7 2.7 1.6 1 0 0 1 1 1 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AAZ35574.1 - 0.0038 17.0 0.5 0.011 15.6 0.5 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme OEP PF02321.18 AAZ35574.1 - 0.049 13.4 9.0 0.079 12.8 9.0 1.2 1 0 0 1 1 1 0 Outer membrane efflux protein DUF4139 PF13598.6 AAZ35574.1 - 0.1 12.3 0.8 0.17 11.6 0.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4139) Sfi1_C PF10638.9 AAZ35574.1 - 0.11 13.3 0.0 0.2 12.4 0.0 1.3 1 0 0 1 1 1 0 Spindle body associated protein C-terminus Response_reg PF00072.24 AAZ35575.1 - 7.3e-25 87.3 0.0 1.2e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain APH PF01636.23 AAZ35576.1 - 1e-47 163.1 0.2 1.4e-47 162.6 0.2 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 AAZ35576.1 - 0.021 14.4 0.0 0.041 13.5 0.0 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase Acetyltransf_1 PF00583.25 AAZ35577.1 - 2.2e-16 60.2 0.0 2.6e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AAZ35577.1 - 9.4e-11 41.7 0.0 1.2e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAZ35577.1 - 6.4e-10 39.3 0.0 9.1e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAZ35577.1 - 9.5e-07 28.7 0.0 1.3e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 AAZ35577.1 - 0.0068 16.5 0.0 0.31 11.1 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AAZ35577.1 - 0.035 14.8 0.0 0.051 14.3 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PepSY PF03413.19 AAZ35578.1 - 7e-12 45.7 0.7 1.3e-11 44.9 0.7 1.3 1 0 0 1 1 1 1 Peptidase propeptide and YPEB domain PepSY_2 PF13670.6 AAZ35578.1 - 0.00028 20.8 7.1 0.0007 19.5 7.1 1.6 1 1 0 1 1 1 1 Peptidase propeptide and YPEB domain FemAB_like PF04339.12 AAZ35579.1 - 5e-148 493.2 0.1 5.7e-148 493.0 0.1 1.0 1 0 0 1 1 1 1 Peptidogalycan biosysnthesis/recognition Acetyltransf_6 PF13480.7 AAZ35579.1 - 1.9e-15 57.3 5.7 6.8e-15 55.5 0.8 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain MFS_3 PF05977.13 AAZ35580.1 - 3.7e-37 127.9 24.9 4.3e-37 127.7 24.9 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1 PF07690.16 AAZ35580.1 - 1.2e-22 80.4 39.7 1.2e-22 80.4 39.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily T2SSM PF04612.12 AAZ35581.1 - 3e-25 89.1 4.2 4.1e-25 88.7 4.2 1.2 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein M TetR_C_33 PF13305.6 AAZ35581.1 - 0.048 14.4 0.1 0.32 11.8 0.0 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain adh_short_C2 PF13561.6 AAZ35582.1 - 6.7e-84 281.1 0.1 7.6e-84 280.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAZ35582.1 - 2.4e-18 66.3 0.0 3e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase DUF2102 PF09875.9 AAZ35582.1 - 0.017 14.8 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2102) Aldedh PF00171.22 AAZ35583.1 - 2.2e-140 468.3 0.0 2.5e-140 468.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 AAZ35583.1 - 0.00032 19.9 0.0 0.00045 19.4 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) BPD_transp_2 PF02653.16 AAZ35584.1 - 2.6e-44 151.4 28.6 2.6e-44 151.4 28.6 1.4 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component FecCD PF01032.18 AAZ35584.1 - 0.033 13.2 27.5 0.52 9.3 10.8 3.1 3 0 0 3 3 3 0 FecCD transport family HKR_ArcB_TM PF18415.1 AAZ35584.1 - 0.15 12.9 0.2 0.15 12.9 0.2 3.4 3 0 0 3 3 3 0 Histidine kinase receptor ArcB trans-membrane domain GTP_EFTU PF00009.27 AAZ35585.1 - 3.4e-64 216.0 0.0 5.4e-64 215.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 AAZ35585.1 - 1.1e-43 147.9 0.2 2.2e-43 146.9 0.2 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 AAZ35585.1 - 9.1e-36 121.8 0.2 4.9e-35 119.5 0.1 2.3 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_C PF00679.24 AAZ35585.1 - 2.5e-30 104.3 0.1 8.1e-30 102.7 0.1 2.0 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 AAZ35585.1 - 1.4e-16 60.6 1.6 3.8e-16 59.2 1.6 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 AAZ35585.1 - 1.2e-06 28.4 0.2 4.1e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 AAZ35585.1 - 0.0043 17.1 0.0 0.0098 16.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase MFS_1 PF07690.16 AAZ35586.1 - 2.1e-14 53.2 48.5 5.3e-08 32.2 15.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MaoC_dehydratas PF01575.19 AAZ35587.1 - 3.6e-25 87.9 0.0 5e-25 87.5 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 AAZ35587.1 - 6.7e-11 42.5 0.0 1.2e-10 41.6 0.0 1.4 1 1 0 1 1 1 1 N-terminal half of MaoC dehydratase 4HBT PF03061.22 AAZ35587.1 - 0.0083 16.5 0.0 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily FlgH PF02107.16 AAZ35587.1 - 0.19 11.3 0.0 14 5.3 0.0 2.2 1 1 1 2 2 2 0 Flagellar L-ring protein Tail_P2_I PF09684.10 AAZ35588.1 - 2.6e-08 33.9 0.2 2.9e-08 33.7 0.2 1.2 1 0 0 1 1 1 1 Phage tail protein (Tail_P2_I) SMBP PF16785.5 AAZ35589.1 - 0.001 19.2 3.1 0.0012 19.0 3.1 1.1 1 0 0 1 1 1 1 Small metal-binding protein T2SSG PF08334.11 AAZ35590.1 - 3.4e-29 101.1 0.1 4e-29 100.8 0.1 1.1 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein G N_methyl PF07963.12 AAZ35590.1 - 5.7e-08 32.0 3.7 7.8e-08 31.6 3.7 1.2 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif Response_reg PF00072.24 AAZ35591.1 - 5.1e-31 107.1 0.1 5.7e-31 107.0 0.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Glycos_transf_1 PF00534.20 AAZ35591.1 - 0.0043 16.6 0.1 0.0065 16.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Sulfotransfer_3 PF13469.6 AAZ35592.1 - 0.012 16.0 0.0 0.094 13.1 0.0 2.4 1 1 0 1 1 1 0 Sulfotransferase family Amidase PF01425.21 AAZ35594.1 - 1.3e-109 367.1 1.4 1.6e-109 366.9 1.4 1.0 1 0 0 1 1 1 1 Amidase Glyoxalase_6 PF18029.1 AAZ35594.1 - 0.054 14.3 0.4 16 6.3 0.1 2.5 2 0 0 2 2 2 0 Glyoxalase-like domain tRNA-synt_2b PF00587.25 AAZ35595.1 - 1.4e-43 148.9 0.0 3.1e-43 147.8 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 AAZ35595.1 - 6.7e-21 74.2 0.1 1.5e-20 73.1 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 AAZ35595.1 - 6.9e-14 51.7 0.0 1.5e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 AAZ35595.1 - 1.4e-10 41.0 0.1 3.4e-10 39.8 0.1 1.7 1 0 0 1 1 1 1 TGS domain PepSY PF03413.19 AAZ35596.1 - 8e-07 29.5 0.0 1e-06 29.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase propeptide and YPEB domain DUF1093 PF06486.11 AAZ35596.1 - 0.085 13.5 0.0 0.12 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1093) LprI PF07007.12 AAZ35597.1 - 1.1e-12 48.5 1.8 1.3e-12 48.2 1.8 1.1 1 0 0 1 1 1 1 Lysozyme inhibitor LprI WASH_WAHD PF11945.8 AAZ35597.1 - 0.008 15.7 0.1 0.0097 15.5 0.1 1.1 1 0 0 1 1 1 1 WAHD domain of WASH complex COMM_domain PF07258.14 AAZ35597.1 - 0.049 13.8 0.7 0.14 12.3 0.7 1.9 1 1 0 1 1 1 0 COMM domain Colicin_Pyocin PF01320.18 AAZ35598.1 - 8.4e-37 125.2 1.0 9.4e-37 125.0 1.0 1.0 1 0 0 1 1 1 1 Colicin immunity protein / pyocin immunity protein LPD30 PF18850.1 AAZ35598.1 - 0.12 12.1 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Large polyvalent protein associated domain 30 AP_endonuc_2 PF01261.24 AAZ35599.1 - 1.2e-35 122.9 0.1 1.5e-35 122.6 0.1 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel AP_endonuc_2_N PF07582.12 AAZ35599.1 - 0.034 13.9 1.1 0.072 12.8 0.0 2.1 3 0 0 3 3 3 0 AP endonuclease family 2 C terminus SAM_Exu PF18609.1 AAZ35599.1 - 0.057 13.5 0.0 0.19 11.9 0.0 1.8 1 0 0 1 1 1 0 Exuperantia SAM-like domain ABC_tran PF00005.27 AAZ35600.1 - 9.4e-46 155.7 0.0 2.9e-22 79.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 AAZ35600.1 - 5.1e-22 77.7 0.2 2.8e-20 72.1 0.1 2.4 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 AAZ35600.1 - 9.2e-18 65.1 2.2 0.0022 17.9 0.0 4.4 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAZ35600.1 - 9.2e-08 31.8 1.6 1.2 8.5 0.0 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAZ35600.1 - 7.3e-07 28.8 0.0 0.017 14.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 AAZ35600.1 - 1.9e-06 28.4 0.0 0.00084 19.8 0.0 2.7 3 0 0 3 3 2 1 AAA ATPase domain AAA_14 PF13173.6 AAZ35600.1 - 5.3e-06 26.5 0.0 0.032 14.3 0.0 3.6 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 AAZ35600.1 - 5.9e-06 26.6 0.1 0.095 13.1 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.6 AAZ35600.1 - 6.2e-06 26.5 0.0 0.013 15.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 AAZ35600.1 - 6.4e-06 26.0 0.2 0.011 15.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 AAZ35600.1 - 7.3e-06 26.3 2.6 0.002 18.4 0.1 3.9 3 1 0 3 3 3 1 AAA domain NACHT PF05729.12 AAZ35600.1 - 9.6e-06 25.6 2.1 0.0038 17.2 0.0 3.1 3 0 0 3 3 3 1 NACHT domain AAA PF00004.29 AAZ35600.1 - 3e-05 24.5 0.1 0.026 14.9 0.0 3.1 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 AAZ35600.1 - 3.2e-05 23.8 3.5 0.11 12.1 0.3 2.9 4 0 0 4 4 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 AAZ35600.1 - 4.4e-05 23.5 0.1 0.017 15.0 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 AAZ35600.1 - 5.4e-05 23.4 0.1 0.093 12.9 0.0 2.6 3 0 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.23 AAZ35600.1 - 5.6e-05 23.2 0.0 0.031 14.4 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase MeaB PF03308.16 AAZ35600.1 - 0.0002 20.5 1.4 0.022 13.8 0.0 2.6 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 AAZ35600.1 - 0.00023 21.7 7.5 0.057 13.9 0.1 3.0 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 AAZ35600.1 - 0.0003 20.6 0.0 0.05 13.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 AAZ35600.1 - 0.00056 19.6 0.0 0.16 11.6 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.6 AAZ35600.1 - 0.00067 20.2 0.1 1.2 9.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 AAZ35600.1 - 0.0008 19.4 1.3 0.14 12.1 0.0 3.5 3 0 0 3 3 3 1 NTPase Rad17 PF03215.15 AAZ35600.1 - 0.0014 18.6 0.0 2.2 8.2 0.0 2.7 2 0 0 2 2 2 1 Rad17 P-loop domain ATPase_2 PF01637.18 AAZ35600.1 - 0.0018 18.3 0.5 0.032 14.1 0.0 2.5 3 0 0 3 3 2 1 ATPase domain predominantly from Archaea DUF87 PF01935.17 AAZ35600.1 - 0.002 18.3 1.0 1.7 8.7 0.0 3.6 4 0 0 4 4 4 1 Helicase HerA, central domain MukB PF04310.12 AAZ35600.1 - 0.004 17.0 0.1 0.31 10.8 0.0 2.4 2 0 0 2 2 2 1 MukB N-terminal AAA_7 PF12775.7 AAZ35600.1 - 0.0058 16.2 0.1 0.15 11.6 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region TsaE PF02367.17 AAZ35600.1 - 0.0072 16.3 0.2 0.36 10.8 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE MobB PF03205.14 AAZ35600.1 - 0.0077 16.1 0.0 0.2 11.6 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.17 AAZ35600.1 - 0.009 15.8 0.1 0.064 13.0 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein CLP1_P PF16575.5 AAZ35600.1 - 0.013 15.3 0.1 2.8 7.7 0.0 2.6 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop NB-ARC PF00931.22 AAZ35600.1 - 0.018 14.2 0.4 0.33 10.1 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Mg_chelatase PF01078.21 AAZ35600.1 - 0.023 14.1 0.1 5 6.4 0.0 3.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Roc PF08477.13 AAZ35600.1 - 0.027 14.7 0.2 0.54 10.5 0.0 2.7 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 AAZ35600.1 - 0.031 14.3 0.4 3.3 7.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Septin PF00735.18 AAZ35600.1 - 0.032 13.5 0.1 0.69 9.1 0.0 2.2 2 0 0 2 2 2 0 Septin SL4P PF17618.2 AAZ35600.1 - 0.037 14.1 0.0 15 5.7 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized Strongylid L4 protein Thymidylate_kin PF02223.17 AAZ35600.1 - 0.041 13.6 0.8 5 6.8 0.0 2.9 3 0 0 3 3 3 0 Thymidylate kinase RuvB_N PF05496.12 AAZ35600.1 - 0.046 13.5 0.1 0.58 9.9 0.0 2.6 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 AAZ35600.1 - 0.05 13.2 0.1 3.7 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 AAZ35600.1 - 0.051 13.2 0.8 11 5.5 0.0 3.3 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.9 AAZ35600.1 - 0.052 13.3 0.1 2.8 7.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.22 AAZ35600.1 - 0.079 12.6 0.1 1.8 8.1 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF815 PF05673.13 AAZ35600.1 - 0.1 11.7 0.0 15 4.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.18 AAZ35600.1 - 0.15 11.4 0.1 3.3 7.0 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family BRE1 PF08647.11 AAZ35600.1 - 0.18 11.9 2.9 0.36 10.9 2.9 1.4 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase DUF3584 PF12128.8 AAZ35600.1 - 0.85 7.0 4.8 0.3 8.5 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) AAA_19 PF13245.6 AAZ35600.1 - 1.1 9.6 0.0 1.1 9.6 0.0 3.1 4 0 0 4 4 3 0 AAA domain DUF3301 PF11743.8 AAZ35601.1 - 2e-33 114.0 0.6 2.4e-33 113.6 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3301) NAPRTase PF04095.16 AAZ35602.1 - 1.4e-80 270.4 0.0 1.7e-80 270.1 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 AAZ35602.1 - 1.2e-34 119.3 0.1 2.9e-34 118.1 0.0 1.7 2 0 0 2 2 2 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain LysE PF01810.18 AAZ35604.1 - 1.1e-26 93.5 19.4 1.3e-26 93.3 19.4 1.0 1 0 0 1 1 1 1 LysE type translocator Fumarate_red_C PF02300.17 AAZ35604.1 - 0.0049 16.9 0.3 0.0049 16.9 0.3 2.4 2 1 1 3 3 3 1 Fumarate reductase subunit C MarC PF01914.17 AAZ35605.1 - 6.6e-40 136.7 8.1 7.5e-40 136.5 8.1 1.0 1 0 0 1 1 1 1 MarC family integral membrane protein BacA PF02673.18 AAZ35605.1 - 0.00074 19.3 3.3 0.0054 16.5 0.5 2.0 1 1 1 2 2 2 2 Bacitracin resistance protein BacA DUF4010 PF13194.6 AAZ35605.1 - 0.0059 16.3 4.6 0.16 11.7 0.4 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4010) DUF2070 PF09843.9 AAZ35605.1 - 0.09 11.0 7.4 0.12 10.7 7.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Wzy_C PF04932.15 AAZ35605.1 - 3.6 7.2 7.6 10 5.7 1.0 2.4 2 0 0 2 2 2 0 O-Antigen ligase tRNA_Me_trans PF03054.16 AAZ35606.1 - 6.8e-137 456.0 0.0 7.8e-137 455.8 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.17 AAZ35606.1 - 2.3e-07 30.2 0.0 7.1e-07 28.6 0.0 1.7 2 0 0 2 2 2 1 NAD synthase ThiI PF02568.14 AAZ35606.1 - 4.7e-06 26.3 0.0 6.6e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) QueC PF06508.13 AAZ35606.1 - 0.0018 17.8 0.0 0.0028 17.2 0.0 1.5 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.20 AAZ35606.1 - 0.0051 16.6 0.0 0.014 15.2 0.0 1.9 1 1 0 1 1 1 1 PP-loop family Asn_synthase PF00733.21 AAZ35606.1 - 0.007 16.1 0.0 0.0084 15.8 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase PAPS_reduct PF01507.19 AAZ35606.1 - 0.14 12.2 0.0 0.49 10.4 0.0 1.9 1 1 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Epimerase PF01370.21 AAZ35607.1 - 1.5e-06 27.9 0.0 9.1e-06 25.3 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KdpD PF02702.17 AAZ35608.1 - 2.9e-92 307.9 1.4 3.9e-92 307.4 0.4 1.7 2 0 0 2 2 2 1 Osmosensitive K+ channel His kinase sensor domain DUF4118 PF13493.6 AAZ35608.1 - 2e-23 82.2 8.3 2e-23 82.2 8.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4118) HATPase_c PF02518.26 AAZ35608.1 - 1.7e-20 73.6 0.0 4.2e-20 72.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAZ35608.1 - 1.2e-13 50.8 1.3 1.2e-13 50.8 1.3 3.4 3 1 1 4 4 4 1 His Kinase A (phospho-acceptor) domain Usp PF00582.26 AAZ35608.1 - 1e-11 45.5 4.2 1e-11 45.5 4.2 3.8 5 1 0 5 5 5 1 Universal stress protein family GAF_2 PF13185.6 AAZ35608.1 - 8e-06 26.2 3.3 0.00018 21.8 0.0 3.7 3 0 0 3 3 3 1 GAF domain GAF_3 PF13492.6 AAZ35608.1 - 0.00095 19.5 0.1 0.0046 17.3 0.0 2.3 2 0 0 2 2 2 1 GAF domain HATPase_c_2 PF13581.6 AAZ35608.1 - 0.0011 19.0 0.1 0.022 14.7 0.0 2.6 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain AAA_25 PF13481.6 AAZ35608.1 - 0.13 11.8 3.3 2 8.0 0.8 3.6 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 AAZ35610.1 - 7.1e-56 187.2 0.2 1.7e-27 95.8 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 AAZ35610.1 - 5.5e-31 107.2 0.0 1.8e-15 56.8 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B KH_dom-like PF14714.6 AAZ35610.1 - 5e-26 90.8 0.0 8.8e-26 90.0 0.0 1.4 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal GTP_EFTU PF00009.27 AAZ35610.1 - 4.7e-17 62.2 4.4 4.9e-08 32.7 0.1 5.1 3 2 0 3 3 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 AAZ35610.1 - 5.5e-14 52.6 0.0 0.018 15.1 0.0 4.4 3 1 1 4 4 4 3 Dynamin family AIG1 PF04548.16 AAZ35610.1 - 5.6e-10 38.9 0.0 0.00014 21.3 0.0 2.3 2 0 0 2 2 2 2 AIG1 family RsgA_GTPase PF03193.16 AAZ35610.1 - 5.6e-08 32.9 0.1 0.066 13.1 0.0 3.9 3 1 1 4 4 4 2 RsgA GTPase Roc PF08477.13 AAZ35610.1 - 3e-06 27.5 0.1 0.055 13.7 0.0 3.5 2 2 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 AAZ35610.1 - 6.9e-06 26.6 0.0 0.22 12.0 0.0 3.0 2 1 0 3 3 3 2 ABC transporter Ras PF00071.22 AAZ35610.1 - 1.1e-05 25.1 0.1 0.087 12.4 0.0 3.1 2 1 0 2 2 2 2 Ras family NOG1 PF06858.14 AAZ35610.1 - 3.1e-05 23.7 0.6 0.0036 17.1 0.0 2.9 4 0 0 4 4 2 1 Nucleolar GTP-binding protein 1 (NOG1) AAA_24 PF13479.6 AAZ35610.1 - 3.3e-05 23.7 0.0 0.027 14.2 0.0 3.0 2 1 1 3 3 3 1 AAA domain AAA_22 PF13401.6 AAZ35610.1 - 8.1e-05 22.9 0.0 0.83 9.9 0.0 3.5 5 0 0 5 5 4 2 AAA domain cobW PF02492.19 AAZ35610.1 - 0.00013 21.6 0.7 0.17 11.5 0.0 3.9 2 2 1 4 4 4 1 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.10 AAZ35610.1 - 0.0002 20.9 0.0 0.62 9.5 0.0 2.4 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit SRP54 PF00448.22 AAZ35610.1 - 0.00023 20.9 0.1 0.61 9.7 0.0 2.9 3 0 0 3 3 3 2 SRP54-type protein, GTPase domain TniB PF05621.11 AAZ35610.1 - 0.0017 17.8 0.0 0.92 8.9 0.0 2.6 2 0 0 2 2 2 1 Bacterial TniB protein AAA_18 PF13238.6 AAZ35610.1 - 0.0025 18.3 0.0 1.3 9.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 AAZ35610.1 - 0.0033 17.8 0.0 4 7.9 0.0 2.6 2 0 0 2 2 2 2 RNA helicase NTPase_1 PF03266.15 AAZ35610.1 - 0.0035 17.3 0.0 2.5 8.0 0.0 2.7 2 0 0 2 2 2 1 NTPase AAA_28 PF13521.6 AAZ35610.1 - 0.0057 16.9 0.0 1.6 8.9 0.0 3.1 2 1 1 3 3 3 1 AAA domain MeaB PF03308.16 AAZ35610.1 - 0.0089 15.0 0.0 5 6.0 0.0 3.1 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 AAZ35610.1 - 0.014 15.5 0.0 4.6 7.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 AAZ35610.1 - 0.016 15.0 0.0 2.3 8.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Ploopntkinase3 PF18751.1 AAZ35610.1 - 0.019 14.9 0.0 1 9.2 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 ATP_bind_1 PF03029.17 AAZ35610.1 - 0.024 14.4 0.0 12 5.6 0.0 3.5 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.22 AAZ35610.1 - 0.025 13.8 0.0 7.7 5.6 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain AAA_14 PF13173.6 AAZ35610.1 - 0.031 14.3 0.1 2.1 8.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 AAZ35610.1 - 0.052 13.3 0.0 29 4.4 0.0 3.3 3 2 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Arf PF00025.21 AAZ35610.1 - 0.15 11.5 0.6 4.6 6.7 0.0 3.4 3 1 0 3 3 3 0 ADP-ribosylation factor family FAD_syn PF06574.12 AAZ35611.1 - 1.4e-55 187.5 0.0 2.9e-55 186.5 0.0 1.5 2 0 0 2 2 2 1 FAD synthetase Flavokinase PF01687.17 AAZ35611.1 - 3.9e-36 123.7 0.0 6.3e-36 123.1 0.0 1.3 1 0 0 1 1 1 1 Riboflavin kinase CTP_transf_like PF01467.26 AAZ35611.1 - 0.013 15.7 0.0 0.047 13.9 0.0 1.9 1 1 0 1 1 1 0 Cytidylyltransferase-like ABC_tran PF00005.27 AAZ35612.1 - 3.2e-30 105.4 0.0 4.3e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAZ35612.1 - 4e-12 46.5 4.2 8.6e-06 25.8 0.1 2.9 1 1 2 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAZ35612.1 - 2.9e-07 30.1 0.0 4.9e-07 29.4 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AAZ35612.1 - 0.00013 22.2 1.3 0.0071 16.6 1.3 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAZ35612.1 - 0.00016 22.1 0.2 0.00024 21.5 0.2 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AAZ35612.1 - 0.001 18.8 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_ATPase PF09818.9 AAZ35612.1 - 0.0014 17.5 0.2 0.049 12.4 0.0 2.7 2 1 0 2 2 2 1 Predicted ATPase of the ABC class AAA PF00004.29 AAZ35612.1 - 0.0015 19.0 0.0 1.2 9.5 0.0 2.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 AAZ35612.1 - 0.0052 16.7 0.0 0.026 14.4 0.0 2.2 2 1 0 2 2 2 1 RsgA GTPase TniB PF05621.11 AAZ35612.1 - 0.011 15.2 0.1 0.22 10.9 0.1 2.2 2 0 0 2 2 2 0 Bacterial TniB protein AAA_30 PF13604.6 AAZ35612.1 - 0.011 15.5 0.0 0.057 13.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AAZ35612.1 - 0.016 14.8 0.4 8 6.0 0.0 2.9 2 1 1 3 3 3 0 AAA domain AAA_18 PF13238.6 AAZ35612.1 - 0.027 15.0 0.0 0.083 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 AAZ35612.1 - 0.029 14.4 0.5 1.6 8.7 0.1 2.5 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 AAZ35612.1 - 0.031 14.5 0.1 0.38 11.0 0.1 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 AAZ35612.1 - 0.052 13.8 0.0 0.09 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 AAZ35612.1 - 0.067 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 AAZ35612.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 AAZ35612.1 - 0.26 11.2 2.9 1.2 9.1 2.9 2.2 1 1 0 1 1 1 0 NACHT domain DUF87 PF01935.17 AAZ35612.1 - 0.29 11.2 1.0 0.61 10.1 0.7 1.6 2 0 0 2 2 2 0 Helicase HerA, central domain DDE_3 PF13358.6 AAZ35613.1 - 0.011 15.5 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease TetR_N PF00440.23 AAZ35614.1 - 1.2e-11 44.3 0.1 2.3e-11 43.3 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.6 AAZ35614.1 - 1.4e-09 38.2 0.3 3.5e-09 36.9 0.3 1.7 1 0 0 1 1 1 1 BetI-type transcriptional repressor, C-terminal TetR_C_17 PF17922.1 AAZ35614.1 - 1.1e-05 25.5 0.0 1.6e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_11 PF16859.5 AAZ35614.1 - 0.0028 18.0 0.3 0.0061 16.9 0.3 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_2 PF08361.11 AAZ35614.1 - 0.016 15.3 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 MAATS-type transcriptional repressor, C-terminal region 5-nucleotidase PF06189.12 AAZ35615.1 - 1.1e-114 381.9 0.0 1.3e-114 381.7 0.0 1.0 1 0 0 1 1 1 1 5'-nucleotidase T2SSE PF00437.20 AAZ35616.1 - 4.2e-78 262.2 0.4 6.9e-78 261.5 0.4 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein T2SSE_N PF05157.15 AAZ35616.1 - 9e-14 51.7 0.3 3.5e-13 49.7 0.3 2.0 1 1 0 1 1 1 1 Type II secretion system (T2SS), protein E, N-terminal domain AAA_14 PF13173.6 AAZ35616.1 - 0.00048 20.2 0.0 0.0013 18.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAZ35616.1 - 0.00054 20.4 0.0 0.0013 19.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 AAZ35616.1 - 0.00057 19.9 0.0 0.0041 17.1 0.0 2.1 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_22 PF13401.6 AAZ35616.1 - 0.0009 19.5 0.0 0.0021 18.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAZ35616.1 - 0.0026 17.5 0.0 0.0063 16.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain NTPase_1 PF03266.15 AAZ35616.1 - 0.003 17.5 5.3 0.085 12.8 1.0 3.2 3 1 0 4 4 4 1 NTPase AAA_7 PF12775.7 AAZ35616.1 - 0.0077 15.8 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_23 PF13476.6 AAZ35616.1 - 0.013 16.0 0.1 0.027 15.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 AAZ35616.1 - 0.014 15.7 1.1 0.041 14.2 1.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 AAZ35616.1 - 0.015 15.1 0.0 0.039 13.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 AAZ35616.1 - 0.018 15.5 0.1 0.037 14.5 0.1 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 AAZ35616.1 - 0.018 14.9 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 AAZ35616.1 - 0.031 14.0 0.0 0.071 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 AAZ35616.1 - 0.033 13.8 0.1 0.063 12.9 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ResIII PF04851.15 AAZ35616.1 - 0.033 14.2 0.0 0.058 13.4 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit FtsK_SpoIIIE PF01580.18 AAZ35616.1 - 0.034 13.5 0.0 0.072 12.4 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 AAZ35616.1 - 0.044 13.0 0.0 0.089 12.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 AAZ35616.1 - 0.08 13.5 0.0 0.44 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Microtub_bd PF16796.5 AAZ35616.1 - 0.088 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Microtubule binding AAA_33 PF13671.6 AAZ35616.1 - 0.11 12.7 0.1 0.22 11.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 AAZ35616.1 - 0.17 11.5 0.3 0.47 10.1 0.1 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MobB PF03205.14 AAZ35616.1 - 0.18 11.7 0.1 2.2 8.2 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RLAN PF14401.6 AAZ35617.1 - 2.8e-48 163.4 0.0 7.6e-48 162.0 0.0 1.7 2 0 0 2 2 2 1 RimK-like ATPgrasp N-terminal domain RimK PF08443.11 AAZ35617.1 - 2.9e-08 33.5 0.0 6.5e-08 32.4 0.0 1.5 1 1 0 1 1 1 1 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.13 AAZ35617.1 - 1.4e-07 31.3 0.0 2.6e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 AAZ35617.1 - 6.2e-05 23.1 0.0 0.0013 18.8 0.0 2.7 2 1 0 2 2 2 1 ATP-grasp domain ATP-grasp_4 PF13535.6 AAZ35617.1 - 0.0036 16.9 0.0 0.011 15.3 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_ST PF14397.6 AAZ35617.1 - 0.044 13.0 0.0 0.2 10.9 0.0 2.0 3 0 0 3 3 3 0 Sugar-transfer associated ATP-grasp ATP-grasp PF02222.22 AAZ35617.1 - 0.052 13.1 0.0 0.083 12.5 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain LPAM_1 PF08139.12 AAZ35618.1 - 0.0086 16.5 0.1 0.0086 16.5 0.1 1.6 2 0 0 2 2 2 1 Prokaryotic membrane lipoprotein lipid attachment site DUF883 PF05957.13 AAZ35619.1 - 0.022 15.4 0.6 0.025 15.2 0.6 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Pterin_bind PF00809.22 AAZ35620.1 - 7.5e-82 274.7 0.0 8.8e-82 274.4 0.0 1.1 1 0 0 1 1 1 1 Pterin binding enzyme ACR_tran PF00873.19 AAZ35621.1 - 5.9e-166 554.0 3.2 7.4e-166 553.6 3.2 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family NA37 PF04245.13 AAZ35622.1 - 9.9e-16 58.1 0.0 1.3e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 37-kD nucleoid-associated bacterial protein BPD_transp_1 PF00528.22 AAZ35623.1 - 1.1e-15 57.8 17.2 1.1e-15 57.8 17.2 1.6 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component YqhR PF11085.8 AAZ35623.1 - 4 7.4 8.2 0.83 9.6 3.6 1.9 2 0 0 2 2 2 0 Conserved membrane protein YqhR DUF2929 PF11151.8 AAZ35623.1 - 5.7 7.3 9.6 0.87 9.9 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2929) TMEM70 PF06979.12 AAZ35623.1 - 7.7 6.9 6.7 0.8 10.1 1.7 1.7 2 0 0 2 2 2 0 Assembly, mitochondrial proton-transport ATP synth complex CMD PF02627.20 AAZ35624.1 - 3.7e-27 94.2 0.5 6.3e-27 93.5 0.2 1.5 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family DNA_pol_A_exo1 PF01612.20 AAZ35625.1 - 1.9e-40 138.5 0.0 2.5e-40 138.1 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.23 AAZ35625.1 - 8.3e-21 73.7 5.7 5.9e-18 64.6 0.4 3.0 2 1 0 2 2 2 2 HRDC domain Lipoprotein_3 PF00938.17 AAZ35625.1 - 0.2 11.8 0.0 0.37 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipoprotein rve PF00665.26 AAZ35626.1 - 1.5e-26 92.9 0.0 2.9e-26 92.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain HTH_21 PF13276.6 AAZ35626.1 - 2.8e-18 65.8 0.4 1.1e-16 60.7 1.5 2.4 2 0 0 2 2 2 1 HTH-like domain rve_3 PF13683.6 AAZ35626.1 - 4.6e-10 39.1 0.0 8.9e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_2 PF13333.6 AAZ35626.1 - 0.0022 18.1 0.0 0.0039 17.3 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain adh_short PF00106.25 AAZ35627.1 - 1.1e-46 158.8 0.0 1.2e-46 158.6 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAZ35627.1 - 2.7e-39 135.1 0.0 6.6e-39 133.8 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAZ35627.1 - 6.5e-14 52.2 0.2 8.7e-14 51.8 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AAZ35627.1 - 0.005 16.3 0.1 0.012 15.1 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 AAZ35627.1 - 0.074 12.4 0.0 0.093 12.1 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 AAZ35627.1 - 0.095 11.8 0.0 0.19 10.9 0.0 1.6 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein DNA_processg_A PF02481.15 AAZ35627.1 - 0.26 10.5 1.8 0.29 10.3 0.6 1.7 2 0 0 2 2 2 0 DNA recombination-mediator protein A TonB_dep_Rec PF00593.24 AAZ35628.1 - 1.5e-45 157.0 41.2 1.5e-45 157.0 41.2 2.2 1 1 1 2 2 2 1 TonB dependent receptor OMP_b-brl_3 PF14905.6 AAZ35628.1 - 7.6e-34 117.4 17.4 1.3e-33 116.6 7.1 2.3 2 0 0 2 2 2 2 Outer membrane protein beta-barrel family Plug PF07715.15 AAZ35628.1 - 2.8e-14 53.6 0.6 8.5e-14 52.0 0.6 1.9 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain GST_N_3 PF13417.6 AAZ35629.1 - 4.1e-14 52.7 0.0 1.4e-13 51.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AAZ35629.1 - 3.7e-11 43.2 0.0 8.4e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 AAZ35629.1 - 5.5e-06 26.3 0.1 1.4e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 AAZ35629.1 - 0.00057 20.2 0.0 0.0017 18.7 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 AAZ35629.1 - 0.001 19.7 0.0 0.0022 18.7 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 AAZ35629.1 - 0.018 15.4 0.0 0.052 13.8 0.0 2.0 1 1 0 1 1 1 0 Outer mitochondrial membrane transport complex protein DUF713 PF05218.14 AAZ35629.1 - 0.1 12.4 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF713) FliP PF00813.20 AAZ35630.1 - 9.9e-60 201.7 5.2 1.2e-59 201.4 5.2 1.0 1 0 0 1 1 1 1 FliP family NIF3 PF01784.18 AAZ35631.1 - 2.8e-57 194.2 0.0 3.3e-57 193.9 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Response_reg PF00072.24 AAZ35632.1 - 1.1e-25 89.9 0.1 1.3e-25 89.7 0.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain CBP_GIL PF10995.8 AAZ35632.1 - 0.14 10.8 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis GIL BRCT_3 PF18428.1 AAZ35632.1 - 0.2 11.8 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain GDPD PF03009.17 AAZ35633.1 - 2.2e-37 129.2 0.0 5.6e-37 127.9 0.0 1.7 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family HSP70 PF00012.20 AAZ35634.1 - 1.4e-184 614.6 0.0 1.6e-184 614.4 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 AAZ35634.1 - 9.2e-17 60.8 1.6 3.3e-15 55.7 0.4 2.6 3 0 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.16 AAZ35634.1 - 0.0034 17.1 0.2 0.0093 15.7 0.1 1.7 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Glycos_transf_2 PF00535.26 AAZ35635.1 - 3e-26 92.3 0.0 5.5e-18 65.3 0.0 3.4 3 0 0 3 3 3 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAZ35635.1 - 1.8e-16 60.7 0.5 8.3e-10 38.9 0.0 3.7 3 1 0 3 3 3 2 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 AAZ35635.1 - 3e-08 33.5 0.0 0.17 11.4 0.0 4.1 4 0 0 4 4 4 2 Glycosyltransferase like family 2 NTP_transf_3 PF12804.7 AAZ35635.1 - 4.6e-05 23.8 0.5 0.017 15.5 0.0 3.1 3 0 0 3 3 3 2 MobA-like NTP transferase domain Glyco_tranf_2_5 PF13712.6 AAZ35635.1 - 0.00029 20.6 0.0 0.0014 18.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family Glyco_trans_2_3 PF13632.6 AAZ35635.1 - 0.058 13.3 0.0 8.5 6.2 0.0 3.0 3 1 0 3 3 3 0 Glycosyl transferase family group 2 KdpC PF02669.15 AAZ35636.1 - 0.00014 21.8 0.2 0.00014 21.8 0.2 1.1 1 0 0 1 1 1 1 K+-transporting ATPase, c chain ParE_toxin PF05016.15 AAZ35637.1 - 3.1e-11 43.7 1.1 3.6e-11 43.5 1.1 1.1 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE ParE-like_toxin PF15781.5 AAZ35637.1 - 0.00085 19.2 0.2 0.0014 18.6 0.2 1.3 1 1 0 1 1 1 1 ParE-like toxin of type II bacterial toxin-antitoxin system tRNA-synt_2e PF02091.15 AAZ35638.1 - 9.8e-151 500.7 0.1 1.1e-150 500.4 0.1 1.0 1 0 0 1 1 1 1 Glycyl-tRNA synthetase alpha subunit ACR_tran PF00873.19 AAZ35639.1 - 0 1059.8 23.0 0 1059.6 23.0 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AAZ35639.1 - 4.6e-15 55.4 22.0 3.6e-11 42.6 8.0 2.3 2 0 0 2 2 2 2 MMPL family SecD_SecF PF02355.16 AAZ35639.1 - 4.3e-06 26.2 30.8 0.00082 18.8 2.5 2.9 3 0 0 3 3 3 2 Protein export membrane protein TMEM138 PF14935.6 AAZ35639.1 - 0.12 13.1 0.2 0.12 13.1 0.2 2.4 2 0 0 2 2 2 0 Transmembrane protein 138 Patched PF02460.18 AAZ35639.1 - 1.8 6.5 17.6 3.1 5.8 17.6 1.3 1 0 0 1 1 1 0 Patched family EamA PF00892.20 AAZ35642.1 - 1.3e-27 96.7 43.2 6.2e-14 52.3 17.0 2.1 2 0 0 2 2 2 2 EamA-like transporter family Phage-tail_3 PF13550.6 AAZ35643.1 - 2e-17 63.6 0.0 3.4e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Putative phage tail protein DAO PF01266.24 AAZ35644.1 - 1.3e-60 205.9 0.6 1.4e-60 205.7 0.6 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 AAZ35644.1 - 1.5e-06 27.7 0.1 0.0057 15.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAZ35644.1 - 3.1e-06 26.7 0.0 0.0039 16.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AAZ35644.1 - 3.6e-06 27.1 0.1 8.2e-06 26.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 AAZ35644.1 - 3.7e-05 23.1 0.4 7.4e-05 22.2 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 AAZ35644.1 - 9.4e-05 21.3 0.0 0.14 10.9 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 AAZ35644.1 - 0.00019 20.7 0.4 0.0055 15.8 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 AAZ35644.1 - 0.00082 19.9 0.1 0.00082 19.9 0.1 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AAZ35644.1 - 0.0054 16.1 0.0 0.0088 15.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 AAZ35644.1 - 0.0076 15.1 0.1 0.023 13.6 0.1 1.7 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_9 PF13454.6 AAZ35644.1 - 0.0078 16.2 1.0 0.15 12.0 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 AAZ35644.1 - 0.0082 15.5 0.0 0.014 14.7 0.0 1.4 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase GIDA PF01134.22 AAZ35644.1 - 0.01 15.0 0.4 0.2 10.7 0.0 2.4 3 0 0 3 3 3 0 Glucose inhibited division protein A NAD_binding_7 PF13241.6 AAZ35644.1 - 0.05 14.1 0.0 0.092 13.2 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 AAZ35644.1 - 0.14 12.1 0.1 0.24 11.3 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Potass_KdpF PF09604.10 AAZ35645.1 - 2.6e-08 33.6 0.9 2.7e-08 33.6 0.9 1.0 1 0 0 1 1 1 1 F subunit of K+-transporting ATPase (Potass_KdpF) Complex1_49kDa PF00346.19 AAZ35646.1 - 1.6e-106 355.4 0.0 2.1e-106 355.0 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Complex1_30kDa PF00329.19 AAZ35646.1 - 3.2e-42 144.0 0.0 8.7e-42 142.6 0.0 1.8 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Radical_SAM PF04055.21 AAZ35647.1 - 6.8e-14 52.6 0.0 9.3e-14 52.1 0.0 1.3 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 AAZ35647.1 - 4.1e-12 46.3 0.0 6.1e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 AAZ35647.1 - 2.2e-06 28.0 0.0 3.4e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain NTP_transferase PF00483.23 AAZ35648.1 - 1.9e-31 109.5 0.0 2.6e-31 109.1 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AAZ35648.1 - 4e-07 30.5 0.0 6.4e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hydrolase_3 PF08282.12 AAZ35649.1 - 7.5e-67 225.7 0.0 8.5e-67 225.6 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 AAZ35649.1 - 2.3e-12 47.0 0.1 9.6e-09 35.1 0.1 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 AAZ35649.1 - 1.6e-07 31.8 0.3 0.00018 21.9 0.1 3.0 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AAZ35649.1 - 0.00016 22.1 1.3 1.3 9.4 0.0 3.4 2 2 1 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AAZ35649.1 - 0.00037 20.6 0.0 0.00092 19.3 0.0 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase CitG PF01874.16 AAZ35650.1 - 5.9e-73 245.9 9.0 7.3e-73 245.6 9.0 1.1 1 0 0 1 1 1 1 ATP:dephospho-CoA triphosphoribosyl transferase MannoseP_isomer PF01050.18 AAZ35651.1 - 1.4e-63 213.3 0.2 2.8e-63 212.3 0.2 1.5 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase NTP_transferase PF00483.23 AAZ35651.1 - 2.6e-53 181.2 0.0 4.1e-53 180.5 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AAZ35651.1 - 2.4e-09 37.7 0.1 5.3e-09 36.6 0.1 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain Cupin_2 PF07883.11 AAZ35651.1 - 4.7e-07 29.4 0.1 9.2e-07 28.5 0.1 1.5 1 0 0 1 1 1 1 Cupin domain Methyltransf_5 PF01795.19 AAZ35652.1 - 1.3e-109 366.4 0.0 1.5e-109 366.2 0.0 1.0 1 0 0 1 1 1 1 MraW methylase family Methyltransf_31 PF13847.6 AAZ35652.1 - 0.001 18.9 0.0 0.19 11.5 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 AAZ35652.1 - 0.12 13.1 0.0 0.42 11.3 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain TPR_2 PF07719.17 AAZ35653.1 - 1.1e-17 62.7 9.4 4e-05 23.4 0.0 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 AAZ35653.1 - 3.7e-17 61.3 6.5 7.3e-05 22.4 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 AAZ35653.1 - 2.9e-15 55.1 7.3 0.00065 19.7 0.0 5.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 AAZ35653.1 - 9.2e-14 51.5 9.3 2e-08 34.4 0.5 4.2 1 1 4 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 AAZ35653.1 - 5.6e-11 41.9 7.0 1.1e-05 24.9 0.1 3.9 4 0 0 4 4 4 2 TPR repeat TPR_16 PF13432.6 AAZ35653.1 - 1.2e-10 41.9 6.9 0.00025 21.6 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 AAZ35653.1 - 7.3e-09 35.7 4.9 0.0042 17.3 0.2 3.3 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 AAZ35653.1 - 6.7e-08 32.7 15.0 0.0032 18.2 0.3 5.3 2 1 4 6 6 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 AAZ35653.1 - 1.5e-07 31.1 8.8 0.18 11.7 0.0 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 AAZ35653.1 - 3.3e-07 29.9 9.7 0.039 14.0 0.1 5.1 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 AAZ35653.1 - 4.7e-07 30.2 14.6 0.00019 21.9 1.0 4.1 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 AAZ35653.1 - 0.00014 21.9 7.9 6.6 7.3 0.1 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat HemY_N PF07219.13 AAZ35653.1 - 0.0004 20.6 4.1 0.3 11.3 0.1 3.2 2 2 2 4 4 4 2 HemY protein N-terminus TPR_6 PF13174.6 AAZ35653.1 - 0.00046 20.7 15.2 0.47 11.2 0.1 5.7 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_21 PF09976.9 AAZ35653.1 - 0.0014 18.3 6.3 0.009 15.7 4.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat-like domain TPR_15 PF13429.6 AAZ35653.1 - 0.0016 17.7 4.8 0.0099 15.1 2.2 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 AAZ35653.1 - 0.011 15.8 8.6 0.97 9.6 0.3 3.6 2 1 2 4 4 4 0 Tetratricopeptide repeat CHU_C PF13585.6 AAZ35653.1 - 0.071 13.2 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 C-terminal domain of CHU protein family DUF2989 PF11207.8 AAZ35653.1 - 0.26 11.0 6.3 4.1 7.1 0.4 3.4 1 1 3 4 4 4 0 Protein of unknown function (DUF2989) TPR_3 PF07720.12 AAZ35653.1 - 0.44 10.6 6.4 2.2 8.4 1.2 3.4 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 AAZ35653.1 - 0.45 11.3 2.8 40 5.2 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat Sel1 PF08238.12 AAZ35653.1 - 0.85 10.4 4.1 50 4.8 0.1 3.8 4 0 0 4 4 3 0 Sel1 repeat Adenylsucc_synt PF00709.21 AAZ35654.1 - 1.6e-176 587.4 0.0 1.8e-176 587.2 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Heme_oxygenase PF01126.20 AAZ35655.1 - 3.3e-18 66.2 0.0 4.7e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Heme oxygenase Haem_oxygenas_2 PF14518.6 AAZ35655.1 - 3.2e-06 27.0 0.0 5.9e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Iron-containing redox enzyme TraX PF05857.11 AAZ35656.1 - 2.6e-56 191.1 14.3 2.9e-56 190.9 14.3 1.0 1 0 0 1 1 1 1 TraX protein DUF883 PF05957.13 AAZ35657.1 - 1.2e-24 86.7 0.8 1.4e-24 86.5 0.8 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) PhaP_Bmeg PF09602.10 AAZ35657.1 - 0.033 14.1 1.2 0.041 13.8 1.2 1.1 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) HisKA_3 PF07730.13 AAZ35657.1 - 0.048 14.2 0.5 0.068 13.7 0.5 1.4 1 0 0 1 1 1 0 Histidine kinase Fmp27_WPPW PF10359.9 AAZ35657.1 - 0.076 11.9 1.2 0.083 11.7 1.2 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain AF0941-like PF14591.6 AAZ35657.1 - 0.084 13.4 0.1 0.1 13.1 0.1 1.1 1 0 0 1 1 1 0 AF0941-like PGF-CTERM PF18204.1 AAZ35657.1 - 0.11 12.6 2.8 0.17 11.9 2.8 1.3 1 0 0 1 1 1 0 PGF-CTERM motif GrpE PF01025.19 AAZ35657.1 - 0.11 12.2 1.6 0.13 11.9 1.6 1.1 1 0 0 1 1 1 0 GrpE Ribosomal_L21p PF00829.21 AAZ35659.1 - 2.1e-39 133.8 1.7 2.6e-39 133.6 1.7 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein DUF3237 PF11578.8 AAZ35661.1 - 1.6e-15 57.2 0.0 1.9e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Mur_ligase_M PF08245.12 AAZ35662.1 - 7.7e-27 94.5 0.0 1e-26 94.1 0.0 1.2 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase PF01225.25 AAZ35662.1 - 8e-27 93.4 0.5 3.3e-26 91.4 0.1 2.1 2 0 0 2 2 2 1 Mur ligase family, catalytic domain Mur_ligase_C PF02875.21 AAZ35662.1 - 6.3e-22 77.6 0.0 2e-21 76.0 0.0 1.9 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain BRX_N PF13713.6 AAZ35664.1 - 0.053 13.3 2.4 0.089 12.6 2.4 1.3 1 0 0 1 1 1 0 Transcription factor BRX N-terminal domain Ribosomal_L23 PF00276.20 AAZ35665.1 - 2.6e-29 101.4 0.2 3e-29 101.2 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L23 Y1_Tnp PF01797.16 AAZ35666.1 - 1.8e-17 63.5 0.0 2.3e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Transposase IS200 like dUTPase PF00692.19 AAZ35667.1 - 8.9e-09 35.1 0.0 3.5e-08 33.2 0.0 1.8 1 1 1 2 2 2 1 dUTPase Flagellar_put PF12611.8 AAZ35667.1 - 0.11 12.3 0.4 0.2 11.4 0.4 1.4 1 0 0 1 1 1 0 Putative flagellar Flavoprotein PF02441.19 AAZ35668.1 - 1.5e-24 86.5 0.0 1.9e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein Epimerase PF01370.21 AAZ35669.1 - 6.7e-13 48.7 0.0 1.4e-12 47.6 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 AAZ35669.1 - 1.2e-10 41.6 0.0 1.5e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 AAZ35669.1 - 5.1e-07 29.1 0.0 6.3e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 AAZ35669.1 - 2.6e-05 23.8 0.0 0.055 12.9 0.0 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 AAZ35669.1 - 0.0031 16.6 0.0 0.0099 14.9 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 AAZ35669.1 - 0.039 13.1 0.0 0.059 12.5 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein ApbA PF02558.16 AAZ35669.1 - 0.14 11.8 0.2 0.26 10.9 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA PC-Esterase PF13839.6 AAZ35669.1 - 0.18 11.5 0.0 0.25 11.1 0.0 1.1 1 0 0 1 1 1 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p 2-Hacid_dh_C PF02826.19 AAZ35669.1 - 0.2 11.0 0.0 0.36 10.2 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PilM_2 PF11104.8 AAZ35670.1 - 1.3e-140 468.3 0.3 1.4e-140 468.1 0.3 1.0 1 0 0 1 1 1 1 Type IV pilus assembly protein PilM; FtsA PF14450.6 AAZ35670.1 - 2.2e-12 47.3 0.1 1.1e-11 45.0 0.0 2.0 2 0 0 2 2 2 1 Cell division protein FtsA MreB_Mbl PF06723.13 AAZ35670.1 - 9.8e-06 24.6 2.2 0.035 12.9 0.0 2.6 2 1 1 3 3 3 2 MreB/Mbl protein Actin PF00022.19 AAZ35670.1 - 0.0033 16.1 0.9 0.066 11.8 0.1 2.7 1 1 1 3 3 3 1 Actin DDR PF08841.10 AAZ35670.1 - 0.0039 16.2 1.7 3.6 6.5 0.0 3.1 3 0 0 3 3 3 3 Diol dehydratase reactivase ATPase-like domain FGGY_N PF00370.21 AAZ35670.1 - 0.18 11.4 0.2 0.3 10.6 0.0 1.4 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, N-terminal domain rve PF00665.26 AAZ35671.1 - 3.6e-34 117.5 0.1 5.7e-34 116.9 0.1 1.3 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 AAZ35671.1 - 5.3e-12 46.2 0.0 7.6e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 DDE domain rve_3 PF13683.6 AAZ35671.1 - 7.2e-11 41.7 0.8 7.2e-11 41.7 0.8 1.8 2 0 0 2 2 2 1 Integrase core domain HTH_21 PF13276.6 AAZ35671.1 - 5.3e-10 39.3 1.4 1.3e-09 38.0 0.1 2.2 2 0 0 2 2 2 1 HTH-like domain rve_2 PF13333.6 AAZ35671.1 - 0.005 17.0 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Bro-N PF02498.17 AAZ35672.1 - 4.9e-10 40.0 0.0 7.8e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 BRO family, N-terminal domain Prok-JAB PF14464.6 AAZ35672.1 - 0.026 14.3 0.0 0.039 13.7 0.0 1.3 1 1 0 1 1 1 0 Prokaryotic homologs of the JAB domain Transposase_mut PF00872.18 AAZ35673.1 - 2.7e-117 391.9 0.0 3.3e-117 391.6 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ35673.1 - 7.8e-05 23.0 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain DUF4844 PF16133.5 AAZ35673.1 - 0.23 12.0 0.0 0.55 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) DUF3509 PF12021.8 AAZ35674.1 - 1.4e-29 101.7 0.0 1.5e-29 101.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3509) Transposase_mut PF00872.18 AAZ35675.1 - 1.5e-117 392.7 0.0 1.9e-117 392.3 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ35675.1 - 7.7e-05 23.0 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain DUF4844 PF16133.5 AAZ35675.1 - 0.23 12.0 0.0 0.55 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) AAA_15 PF13175.6 AAZ35676.1 - 4.4e-21 76.0 0.0 1.8e-09 37.8 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 AAZ35676.1 - 5.4e-20 72.4 2.4 2e-18 67.3 2.4 2.5 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AAZ35676.1 - 1.6e-14 54.9 0.0 4.9e-14 53.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 AAZ35676.1 - 6.6e-13 48.6 0.0 1.2e-07 31.4 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_27 PF13514.6 AAZ35676.1 - 8e-06 25.6 0.0 1.7e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 AAZ35676.1 - 0.0015 19.0 0.0 0.034 14.7 0.0 2.5 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 AAZ35676.1 - 0.0032 17.2 0.0 0.0079 15.9 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 AAZ35676.1 - 0.13 11.8 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain tRNA-synt_1d PF00750.19 AAZ35677.1 - 2.7e-127 424.5 0.0 3.3e-127 424.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 AAZ35677.1 - 3e-33 114.5 0.0 8.3e-33 113.1 0.0 1.8 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 AAZ35677.1 - 1.5e-25 89.6 0.0 5.1e-25 87.9 0.0 2.0 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain HATPase_c PF02518.26 AAZ35678.1 - 1.4e-27 96.4 0.2 4.2e-27 94.9 0.2 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AAZ35678.1 - 9e-22 77.4 0.0 3.9e-21 75.3 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 AAZ35678.1 - 1e-15 57.5 1.4 2.5e-15 56.2 0.2 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Hpt PF01627.23 AAZ35678.1 - 3e-06 27.4 0.6 1.2e-05 25.5 0.6 2.1 1 0 0 1 1 1 1 Hpt domain HATPase_c_3 PF13589.6 AAZ35678.1 - 0.00025 20.9 0.0 0.00046 20.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 AAZ35678.1 - 0.19 12.1 0.0 0.44 10.9 0.0 1.7 1 0 0 1 1 1 0 PAS fold GRIP PF01465.20 AAZ35678.1 - 0.4 10.6 2.7 14 5.7 0.4 3.1 3 0 0 3 3 3 0 GRIP domain Tautomerase PF01361.21 AAZ35679.1 - 0.049 13.6 0.2 2.1 8.3 0.0 2.6 2 0 0 2 2 2 0 Tautomerase enzyme eIF3_subunit PF08597.10 AAZ35680.1 - 1.5 8.7 9.0 1.6 8.5 9.0 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF4096 PF13340.6 AAZ35681.1 - 5.8e-25 87.3 0.4 1.5e-24 86.0 0.4 1.8 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1 PF01609.21 AAZ35681.1 - 3.2e-14 53.1 0.0 5.7e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AAZ35681.1 - 7.2e-10 39.1 0.2 2.1e-09 37.6 0.2 1.9 1 0 0 1 1 1 1 Transposase DDE domain HTH_Tnp_Tc3_2 PF01498.18 AAZ35681.1 - 0.061 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Transposase RrnaAD PF00398.20 AAZ35682.1 - 7e-64 215.4 0.0 7.8e-64 215.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.6 AAZ35682.1 - 0.00079 19.3 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAZ35682.1 - 0.0025 18.5 0.0 0.0052 17.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAZ35682.1 - 0.069 13.9 0.0 0.29 11.9 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 AAZ35682.1 - 0.077 13.7 0.0 0.17 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.11 AAZ35682.1 - 0.12 11.9 0.0 0.24 11.0 0.0 1.4 2 0 0 2 2 2 0 Nodulation protein S (NodS) Methyltransf_28 PF02636.17 AAZ35682.1 - 0.13 11.8 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase RsmJ PF04378.13 AAZ35682.1 - 0.18 11.0 0.0 0.55 9.4 0.0 1.7 2 1 1 3 3 3 0 Ribosomal RNA large subunit methyltransferase D, RlmJ GGDEF PF00990.21 AAZ35683.1 - 5.2e-34 117.3 0.1 2.2e-31 108.8 0.1 2.2 1 1 0 1 1 1 1 Diguanylate cyclase, GGDEF domain DUF4658 PF15555.6 AAZ35683.1 - 0.015 15.4 0.6 0.046 13.8 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4658) TraX PF05857.11 AAZ35683.1 - 0.4 10.7 7.9 0.15 12.1 0.5 2.2 1 1 1 2 2 2 0 TraX protein Response_reg PF00072.24 AAZ35684.1 - 7e-24 84.2 0.1 1.9e-23 82.8 0.1 1.8 1 0 0 1 1 1 1 Response regulator receiver domain CheW PF01584.19 AAZ35684.1 - 3.2e-17 62.4 0.9 7.3e-17 61.3 0.9 1.7 1 0 0 1 1 1 1 CheW-like domain Hpt PF01627.23 AAZ35684.1 - 7e-13 48.6 3.3 7e-13 48.6 3.3 3.4 4 0 0 4 4 4 1 Hpt domain HATPase_c PF02518.26 AAZ35684.1 - 2e-12 47.6 0.0 4.3e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase H-kinase_dim PF02895.14 AAZ35684.1 - 0.11 12.9 0.7 0.49 10.8 0.3 2.4 2 0 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain FAP PF07174.11 AAZ35684.1 - 5.5 6.3 12.1 40 3.5 12.3 1.9 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) tRNA-synt_His PF13393.6 AAZ35685.1 - 3.1e-44 151.5 0.0 5.3e-44 150.7 0.0 1.4 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.25 AAZ35685.1 - 8.9e-29 100.7 0.0 1.4e-28 100.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 AAZ35685.1 - 1.9e-06 28.0 0.0 6.4e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2 PF00152.20 AAZ35685.1 - 0.00054 19.1 0.1 0.055 12.6 0.1 2.3 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 AAZ35685.1 - 0.014 14.9 0.0 0.9 9.0 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Atypical_Card PF18461.1 AAZ35685.1 - 0.16 12.2 0.0 14 5.9 0.0 2.3 2 0 0 2 2 2 0 Atypical caspase recruitment domain PAPS_reduct PF01507.19 AAZ35686.1 - 6.3e-67 224.9 0.0 7.8e-67 224.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family LysR_substrate PF03466.20 AAZ35688.1 - 9.4e-30 103.5 1.1 1.2e-29 103.2 1.1 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ35688.1 - 2.4e-16 59.4 0.0 5.6e-16 58.3 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MlaA PF04333.13 AAZ35689.1 - 9.3e-74 247.4 0.2 1.1e-73 247.1 0.2 1.0 1 0 0 1 1 1 1 MlaA lipoprotein Fer2_2 PF01799.20 AAZ35690.1 - 1.4e-31 108.3 1.2 1.4e-31 108.3 1.2 2.0 2 0 0 2 2 2 1 [2Fe-2S] binding domain Fer2 PF00111.27 AAZ35690.1 - 1.1e-06 28.5 0.7 1.1e-06 28.5 0.7 1.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 AAZ35690.1 - 0.002 18.1 1.4 0.002 18.1 1.4 1.5 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Response_reg PF00072.24 AAZ35691.1 - 1.4e-20 73.5 0.1 2e-20 73.0 0.1 1.2 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AAZ35691.1 - 1.3e-12 47.0 0.2 1.9e-12 46.5 0.2 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_23 PF13384.6 AAZ35691.1 - 0.0081 15.9 0.1 0.018 14.8 0.1 1.5 1 0 0 1 1 1 1 Homeodomain-like domain Trp_repressor PF01371.19 AAZ35691.1 - 0.02 15.0 0.1 0.054 13.6 0.1 1.7 1 0 0 1 1 1 0 Trp repressor protein HTH_38 PF13936.6 AAZ35691.1 - 0.033 14.0 0.0 0.067 13.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_31 PF13560.6 AAZ35691.1 - 0.039 14.3 0.1 0.071 13.5 0.1 1.6 1 1 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 AAZ35691.1 - 0.063 12.8 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 DUF4810 PF16068.5 AAZ35692.1 - 3.5e-32 110.8 1.2 4.3e-32 110.5 1.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4810) Pectate_lyase PF03211.13 AAZ35693.1 - 1.8e-45 155.0 12.0 3e-45 154.3 12.0 1.3 1 0 0 1 1 1 1 Pectate lyase DUF4140 PF13600.6 AAZ35693.1 - 0.0064 16.9 0.1 0.013 15.9 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of unknown function (DUF4140) Beta_helix PF13229.6 AAZ35693.1 - 0.082 12.8 8.3 0.15 11.9 7.5 1.9 2 1 0 2 2 2 0 Right handed beta helix region CheR PF01739.18 AAZ35694.1 - 4.5e-56 189.4 0.0 6.3e-56 188.9 0.0 1.1 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain CheR_N PF03705.15 AAZ35694.1 - 6.6e-13 48.2 0.2 1.3e-12 47.2 0.2 1.5 1 0 0 1 1 1 1 CheR methyltransferase, all-alpha domain Methyltransf_25 PF13649.6 AAZ35694.1 - 2.1e-07 31.5 0.0 0.00032 21.4 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 AAZ35694.1 - 1e-06 28.7 0.0 0.00016 21.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAZ35694.1 - 2e-06 28.5 0.0 0.011 16.5 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 AAZ35694.1 - 2.2e-05 25.0 0.0 0.00044 20.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain NAS PF03059.16 AAZ35694.1 - 5.3e-05 22.7 0.0 7.6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Nicotianamine synthase protein Methyltransf_23 PF13489.6 AAZ35694.1 - 0.0011 18.9 0.0 0.0016 18.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.12 AAZ35694.1 - 0.14 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_2 PF00891.18 AAZ35694.1 - 0.16 11.2 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Acetyltransf_1 PF00583.25 AAZ35695.1 - 9.4e-13 48.4 0.0 3.1e-12 46.8 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family RimK PF08443.11 AAZ35695.1 - 5.3e-10 39.2 0.0 0.00014 21.6 0.1 2.3 2 0 0 2 2 2 2 RimK-like ATP-grasp domain Acetyltransf_7 PF13508.7 AAZ35695.1 - 1.7e-08 34.8 0.0 2.5e-07 31.0 0.0 2.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAZ35695.1 - 1.1e-06 28.5 0.0 2.6e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein GSH-S_ATP PF02955.16 AAZ35695.1 - 1.2e-06 28.0 0.1 2.2e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain Acetyltransf_10 PF13673.7 AAZ35695.1 - 1.9e-06 27.8 0.0 4.2e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ATPgrasp_YheCD PF14398.6 AAZ35695.1 - 3.3e-05 23.3 0.0 0.00014 21.2 0.0 2.0 2 1 0 2 2 2 1 YheC/D like ATP-grasp Acetyltransf_6 PF13480.7 AAZ35695.1 - 0.00014 22.1 0.1 0.00091 19.4 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Dala_Dala_lig_C PF07478.13 AAZ35695.1 - 0.00017 21.2 0.1 0.00041 20.0 0.1 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_ST PF14397.6 AAZ35695.1 - 0.00034 19.9 0.1 0.013 14.7 0.0 2.7 2 1 1 3 3 3 1 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 AAZ35695.1 - 0.0009 19.3 0.0 0.0083 16.2 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp domain SBP_bac_3 PF00497.20 AAZ35696.1 - 5e-31 107.9 0.0 6.7e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1 PF09084.11 AAZ35696.1 - 0.0017 18.3 0.0 0.0084 16.1 0.0 1.9 1 1 1 2 2 2 1 NMT1/THI5 like OpuAC PF04069.12 AAZ35697.1 - 1.9e-66 224.3 0.0 2.2e-66 224.1 0.0 1.1 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system CorA PF01544.18 AAZ35698.1 - 1e-51 176.0 0.0 1.2e-51 175.8 0.0 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Biotin_lipoyl PF00364.22 AAZ35699.1 - 1.6e-17 63.1 0.1 3e-17 62.2 0.1 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 AAZ35699.1 - 1.3e-05 24.9 4.7 0.0001 22.1 0.1 2.9 3 0 0 3 3 3 1 Biotin-lipoyl like HlyD_D23 PF16576.5 AAZ35699.1 - 0.0013 18.0 0.4 0.0048 16.2 0.2 1.8 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion RnfC_N PF13375.6 AAZ35699.1 - 0.004 17.1 1.1 0.022 14.7 0.9 2.0 1 1 1 2 2 2 2 RnfC Barrel sandwich hybrid domain GCV_H PF01597.19 AAZ35699.1 - 0.023 14.6 0.2 0.046 13.6 0.2 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein HlyD_3 PF13437.6 AAZ35699.1 - 0.023 15.4 1.3 0.084 13.6 0.2 2.2 2 0 0 2 2 2 0 HlyD family secretion protein DUF883 PF05957.13 AAZ35700.1 - 2.2e-21 76.3 0.7 3.2e-21 75.7 0.4 1.4 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF883) ApoLp-III PF07464.11 AAZ35700.1 - 0.019 15.1 3.2 0.023 14.8 3.2 1.1 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF1451 PF07295.11 AAZ35700.1 - 0.019 15.0 0.4 0.021 14.9 0.4 1.1 1 0 0 1 1 1 0 Zinc-ribbon containing domain MRP-L47 PF06984.13 AAZ35700.1 - 0.038 14.1 0.1 0.073 13.2 0.0 1.5 1 1 1 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Met_synt_B12 PF02965.17 AAZ35701.1 - 1.2e-118 395.6 0.0 1.8e-118 395.0 0.0 1.3 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain S-methyl_trans PF02574.16 AAZ35701.1 - 2.2e-77 260.5 0.0 4.5e-77 259.5 0.0 1.6 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Pterin_bind PF00809.22 AAZ35701.1 - 1.1e-56 192.3 0.1 2.8e-56 190.9 0.1 1.8 1 0 0 1 1 1 1 Pterin binding enzyme B12-binding_2 PF02607.17 AAZ35701.1 - 9.6e-24 83.6 0.2 3e-23 82.0 0.2 2.0 1 0 0 1 1 1 1 B12 binding domain B12-binding PF02310.19 AAZ35701.1 - 1.5e-19 70.2 0.3 6.7e-19 68.1 0.3 2.2 1 0 0 1 1 1 1 B12 binding domain PAP2 PF01569.21 AAZ35702.1 - 1.6e-17 63.5 2.4 3.1e-17 62.6 2.4 1.5 1 0 0 1 1 1 1 PAP2 superfamily EamA PF00892.20 AAZ35702.1 - 0.081 13.1 5.7 1.2 9.3 0.2 3.1 3 0 0 3 3 3 0 EamA-like transporter family ResB PF05140.14 AAZ35702.1 - 0.18 10.5 0.1 0.25 10.1 0.1 1.2 1 0 0 1 1 1 0 ResB-like family CYSTM PF12734.7 AAZ35703.1 - 0.062 13.6 1.4 0.13 12.6 1.4 1.5 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance DUF2059 PF09832.9 AAZ35703.1 - 0.12 12.4 0.9 0.49 10.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2059) PhdYeFM_antitox PF02604.19 AAZ35704.1 - 1.3e-09 37.7 0.0 1.7e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Antitoxin Phd_YefM, type II toxin-antitoxin system Aldose_epim PF01263.20 AAZ35705.1 - 3.9e-25 88.8 0.0 4.7e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase ZipA_C PF04354.13 AAZ35706.1 - 2.7e-48 163.1 0.1 3.6e-48 162.6 0.1 1.2 1 0 0 1 1 1 1 ZipA, C-terminal FtsZ-binding domain SIS_2 PF13580.6 AAZ35707.1 - 8.3e-37 126.3 0.5 1e-36 126.0 0.5 1.1 1 0 0 1 1 1 1 SIS domain SIS PF01380.22 AAZ35707.1 - 6.3e-07 29.3 0.1 1e-06 28.6 0.1 1.4 1 0 0 1 1 1 1 SIS domain CoA_transf_3 PF02515.17 AAZ35708.1 - 7.4e-126 420.2 0.0 8.5e-126 420.0 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III Phage_integrase PF00589.22 AAZ35709.1 - 2.9e-23 82.5 0.0 4.3e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_5 PF13102.6 AAZ35709.1 - 0.061 13.7 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Phage integrase SAM-like domain DUF2555 PF10742.9 AAZ35709.1 - 0.088 12.6 0.1 14 5.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2555) Form_Nir_trans PF01226.17 AAZ35710.1 - 1.2e-42 145.9 17.9 1.4e-42 145.7 17.9 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter SMC_N PF02463.19 AAZ35711.1 - 3.3e-16 59.4 0.0 8.1e-16 58.1 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AAZ35711.1 - 3.9e-12 47.1 4.9 7.3e-11 42.9 4.9 2.4 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAZ35711.1 - 1.6e-05 24.5 0.1 3.2e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain COG6 PF06419.11 AAZ35711.1 - 0.0008 17.8 2.9 0.0008 17.8 2.9 1.9 2 0 0 2 2 2 1 Conserved oligomeric complex COG6 ABC_tran PF00005.27 AAZ35711.1 - 0.0012 19.4 5.4 0.58 10.7 0.6 3.8 3 1 0 3 3 3 2 ABC transporter NAPRTase_N PF17767.1 AAZ35711.1 - 0.0017 18.7 2.0 0.76 10.2 0.1 3.3 3 0 0 3 3 3 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Peptidase_M9_N PF08453.10 AAZ35711.1 - 0.004 16.9 0.0 0.012 15.3 0.0 1.8 1 0 0 1 1 1 1 Peptidase family M9 N-terminal RsgA_GTPase PF03193.16 AAZ35711.1 - 0.0045 16.9 0.6 0.022 14.7 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase NTPase_P4 PF11602.8 AAZ35711.1 - 0.011 15.0 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 AAA_21 PF13304.6 AAZ35711.1 - 0.013 15.3 0.1 2.6 7.8 0.0 2.5 2 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system HMMR_N PF15905.5 AAZ35711.1 - 0.014 14.9 2.1 0.014 14.9 2.1 2.2 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Nif11 PF07862.11 AAZ35711.1 - 0.022 15.1 0.3 3.6 8.0 0.1 2.9 2 0 0 2 2 2 0 Nif11 domain MHC_II_beta PF00969.19 AAZ35711.1 - 0.024 14.7 0.7 0.61 10.2 0.1 2.8 2 0 0 2 2 2 0 Class II histocompatibility antigen, beta domain AAA_22 PF13401.6 AAZ35711.1 - 0.035 14.4 10.8 0.051 13.8 0.0 4.3 3 1 1 4 4 3 0 AAA domain FAA_hydro_N_2 PF18288.1 AAZ35711.1 - 0.05 14.0 2.0 7.7 7.0 0.2 3.1 2 1 1 3 3 3 0 Fumarylacetoacetase N-terminal domain 2 AAA_15 PF13175.6 AAZ35711.1 - 0.14 11.8 0.0 0.52 10.0 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Spc29 PF17082.5 AAZ35711.1 - 0.3 10.9 6.6 0.078 12.8 0.9 2.2 2 0 0 2 2 2 0 Spindle Pole Component 29 V_ATPase_I PF01496.19 AAZ35711.1 - 0.6 8.0 7.8 0.99 7.2 0.8 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family UPF0242 PF06785.11 AAZ35711.1 - 3.6 7.6 17.9 0.6 10.2 3.6 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TMF_TATA_bd PF12325.8 AAZ35711.1 - 3.8 7.8 20.4 4.6 7.5 10.1 2.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.15 AAZ35711.1 - 4.4 7.1 0.0 4.4 7.1 0.0 4.7 3 2 3 6 6 6 0 Septum formation initiator PilJ PF13675.6 AAZ35711.1 - 4.5 7.3 12.0 0.47 10.5 2.1 3.3 2 1 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF87 PF01935.17 AAZ35711.1 - 7.6 6.6 10.0 1.1e+02 2.8 0.0 3.3 2 1 0 2 2 2 0 Helicase HerA, central domain TonB_dep_Rec PF00593.24 AAZ35712.1 - 3e-65 221.9 36.4 3e-65 221.9 36.4 1.7 2 0 0 2 2 2 1 TonB dependent receptor Plug PF07715.15 AAZ35712.1 - 2.2e-27 95.8 1.7 7.5e-27 94.0 1.7 2.0 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 AAZ35712.1 - 2.6e-11 43.2 3.4 2.6e-11 43.2 3.4 1.7 2 0 0 2 2 2 1 Outer membrane protein beta-barrel family STN PF07660.14 AAZ35712.1 - 2.1e-07 30.6 0.2 6.1e-07 29.1 0.2 1.9 1 0 0 1 1 1 1 Secretin and TonB N terminus short domain OpgC_C PF10129.9 AAZ35713.1 - 3.2e-114 381.5 19.8 3.6e-114 381.4 19.8 1.0 1 0 0 1 1 1 1 OpgC protein DUF2754 PF10953.8 AAZ35713.1 - 5.1 7.4 6.6 26 5.1 0.3 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2754) PsbT PF01405.17 AAZ35713.1 - 8.9 6.2 8.5 4.6 7.1 3.9 2.8 2 0 0 2 2 2 0 Photosystem II reaction centre T protein B3_4 PF03483.17 AAZ35714.1 - 7.9e-71 237.3 0.0 1.2e-70 236.8 0.0 1.2 1 0 0 1 1 1 1 B3/4 domain tRNA_synthFbeta PF17759.1 AAZ35714.1 - 6.9e-60 202.1 0.0 2.6e-59 200.2 0.0 1.9 2 0 0 2 2 2 1 Phenylalanyl tRNA synthetase beta chain CLM domain FDX-ACB PF03147.14 AAZ35714.1 - 8.2e-29 99.9 0.0 1.5e-28 99.0 0.0 1.5 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain tRNA_bind PF01588.20 AAZ35714.1 - 2.3e-24 85.3 0.1 3.9e-24 84.6 0.1 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain B5 PF03484.15 AAZ35714.1 - 1.5e-20 73.3 0.0 8e-20 70.9 0.1 2.3 2 1 0 2 2 2 1 tRNA synthetase B5 domain PhetRS_B1 PF18262.1 AAZ35714.1 - 0.12 12.6 0.0 8.4 6.7 0.0 2.9 3 1 0 3 3 3 0 Phe-tRNA synthetase beta subunit B1 domain AnmK PF03702.14 AAZ35715.1 - 5e-157 522.7 0.0 5.7e-157 522.5 0.0 1.0 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase CobS_N PF12556.8 AAZ35715.1 - 0.00038 20.1 0.4 0.0014 18.3 0.0 2.2 2 0 0 2 2 2 1 Cobaltochelatase CobS subunit N terminal FGGY_C PF02782.16 AAZ35715.1 - 0.01 15.5 0.1 0.03 14.1 0.0 1.8 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain ADPRTs_Tse2 PF18648.1 AAZ35715.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Tse2 ADP-ribosyltransferase toxins Response_reg PF00072.24 AAZ35716.1 - 1.7e-60 202.1 7.2 2.2e-27 95.4 0.8 3.8 3 0 0 3 3 3 3 Response regulator receiver domain CHASE3 PF05227.13 AAZ35716.1 - 3.7e-36 124.1 3.7 3.7e-36 124.1 3.7 3.3 2 1 0 2 2 1 1 CHASE3 domain HATPase_c PF02518.26 AAZ35716.1 - 1.7e-27 96.2 0.0 3.7e-27 95.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_2 PF13185.6 AAZ35716.1 - 3.7e-17 62.9 1.0 1.2e-16 61.2 0.1 2.4 3 0 0 3 3 2 1 GAF domain HisKA PF00512.25 AAZ35716.1 - 2.5e-15 56.2 0.1 2.5e-15 56.2 0.1 4.1 3 1 0 3 3 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 AAZ35716.1 - 1.1e-11 45.5 0.0 7e-11 42.9 0.0 2.5 3 0 0 3 3 1 1 GAF domain GAF_3 PF13492.6 AAZ35716.1 - 2.5e-06 27.8 0.0 8.1e-06 26.2 0.0 1.9 1 0 0 1 1 1 1 GAF domain ERM PF00769.19 AAZ35716.1 - 0.00056 19.8 21.5 0.0014 18.5 21.5 1.7 1 0 0 1 1 1 1 Ezrin/radixin/moesin family FPP PF05911.11 AAZ35716.1 - 0.0011 17.3 12.7 0.0022 16.3 12.7 1.4 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil HATPase_c_3 PF13589.6 AAZ35716.1 - 0.017 15.0 0.1 0.12 12.2 0.0 2.2 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IFT57 PF10498.9 AAZ35716.1 - 0.02 13.9 10.7 0.042 12.8 10.7 1.5 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Atg14 PF10186.9 AAZ35716.1 - 0.029 13.5 16.8 0.071 12.2 16.8 1.6 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Baculo_11_kDa PF06143.11 AAZ35716.1 - 0.085 12.4 0.3 0.6 9.7 0.0 2.5 2 0 0 2 2 2 0 Baculovirus 11 kDa family Borrelia_P83 PF05262.11 AAZ35716.1 - 0.16 10.5 11.1 0.3 9.5 11.1 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein FAM76 PF16046.5 AAZ35716.1 - 0.17 11.2 6.1 0.34 10.2 6.1 1.5 1 0 0 1 1 1 0 FAM76 protein YscO-like PF16789.5 AAZ35716.1 - 0.37 10.8 24.1 0.23 11.5 3.0 4.1 3 1 1 4 4 4 0 YscO-like protein Exonuc_VII_L PF02601.15 AAZ35716.1 - 0.42 10.1 22.6 0.49 9.9 14.8 3.1 3 0 0 3 3 3 0 Exonuclease VII, large subunit HMMR_N PF15905.5 AAZ35716.1 - 1.3 8.5 21.1 3.1 7.2 21.1 1.6 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Asp-B-Hydro_N PF05279.11 AAZ35716.1 - 1.6 8.7 13.2 1.3 9.0 10.6 2.0 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region GAS PF13851.6 AAZ35716.1 - 1.7 7.9 25.8 0.14 11.5 20.3 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 AAZ35716.1 - 2.4 7.0 27.8 0.57 9.0 24.1 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein bZIP_1 PF00170.21 AAZ35716.1 - 2.6 8.2 21.6 1.9 8.7 2.4 3.7 2 1 1 3 3 3 0 bZIP transcription factor V_ATPase_I PF01496.19 AAZ35716.1 - 2.8 5.7 9.9 6.1 4.6 9.9 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YjcZ PF13990.6 AAZ35716.1 - 3.3 7.0 11.6 8.4 5.7 11.6 1.6 1 0 0 1 1 1 0 YjcZ-like protein CAML PF14963.6 AAZ35716.1 - 4.4 7.4 6.4 4.3 7.4 0.0 2.3 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand TMPIT PF07851.13 AAZ35716.1 - 5.9 6.0 11.7 0.7 9.1 6.7 2.0 2 0 0 2 2 2 0 TMPIT-like protein Syntaxin-6_N PF09177.11 AAZ35716.1 - 6.6 7.4 14.5 62 4.2 14.3 2.7 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF4337 PF14235.6 AAZ35716.1 - 9.5 6.3 12.9 27 4.8 12.9 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) UPF0242 PF06785.11 AAZ35716.1 - 10 6.2 23.3 6.5 6.8 20.3 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DNA_pol3_delta PF06144.13 AAZ35717.1 - 2.5e-31 108.8 0.0 3.5e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DNA_pol3_delt_C PF14840.6 AAZ35717.1 - 2.1e-14 54.0 0.1 4.8e-14 52.8 0.1 1.6 1 0 0 1 1 1 1 Processivity clamp loader gamma complex DNA pol III C-term DNA_pol3_gamma3 PF12169.8 AAZ35717.1 - 0.0076 16.2 0.8 0.055 13.4 0.0 2.3 1 1 1 2 2 2 1 DNA polymerase III subunits gamma and tau domain III CCCAP PF15964.5 AAZ35717.1 - 0.041 12.2 0.0 0.054 11.8 0.0 1.1 1 0 0 1 1 1 0 Centrosomal colon cancer autoantigen protein family Abhydrolase_3 PF07859.13 AAZ35718.1 - 2.3e-72 243.2 1.4 2.7e-72 243.1 0.7 1.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 AAZ35718.1 - 2.4e-06 26.6 0.0 3.6e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 AAZ35718.1 - 2e-05 24.2 0.5 6e-05 22.6 0.5 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 AAZ35718.1 - 0.00034 19.6 1.6 0.0031 16.5 1.6 2.0 1 1 0 1 1 1 1 Carboxylesterase family Chlorophyllase PF07224.11 AAZ35718.1 - 0.001 18.2 0.2 0.0019 17.3 0.2 1.4 1 1 0 1 1 1 1 Chlorophyllase AXE1 PF05448.12 AAZ35718.1 - 0.003 16.3 0.1 0.29 9.8 0.1 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Mak_N_cap PF18085.1 AAZ35718.1 - 0.015 16.3 0.2 3.1 8.9 0.0 2.7 1 1 0 2 2 2 0 Maltokinase N-terminal cap domain DUF2974 PF11187.8 AAZ35718.1 - 0.097 12.2 0.4 0.18 11.3 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) Lipase_3 PF01764.25 AAZ35718.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) TerD PF02342.18 AAZ35719.1 - 6.5e-49 166.0 0.0 7.4e-49 165.8 0.0 1.0 1 0 0 1 1 1 1 TerD domain HlyD_D23 PF16576.5 AAZ35720.1 - 1.9e-15 56.7 4.5 2.5e-14 53.0 4.5 2.2 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD PF00529.20 AAZ35720.1 - 1.3e-09 37.8 1.8 1.6e-09 37.5 0.7 1.7 2 0 0 2 2 2 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl_2 PF13533.6 AAZ35720.1 - 1.1e-08 34.8 6.2 6.3e-08 32.3 0.3 3.2 3 0 0 3 3 3 1 Biotin-lipoyl like HlyD_3 PF13437.6 AAZ35720.1 - 3.1e-07 31.0 1.7 0.00026 21.7 0.2 3.4 2 1 0 2 2 2 2 HlyD family secretion protein PTS_EIIA_1 PF00358.20 AAZ35720.1 - 0.0056 16.4 0.2 4 7.2 0.0 3.2 3 0 0 3 3 3 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 DUF4994 PF16385.5 AAZ35720.1 - 0.011 15.6 0.1 0.23 11.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF4061 PF13270.6 AAZ35720.1 - 0.15 12.4 0.8 0.28 11.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) OEP PF02321.18 AAZ35720.1 - 0.16 11.7 12.1 0.82 9.4 10.6 2.1 2 0 0 2 2 2 0 Outer membrane efflux protein DUF4407 PF14362.6 AAZ35720.1 - 0.35 10.2 6.1 0.52 9.6 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2203 PF09969.9 AAZ35720.1 - 0.43 11.3 3.3 13 6.5 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Gp_dh_C PF02800.20 AAZ35721.1 - 5.4e-45 152.8 0.3 8.9e-45 152.1 0.3 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 AAZ35721.1 - 4.7e-20 71.8 0.5 2.8e-19 69.3 0.1 2.4 2 1 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain LysR_substrate PF03466.20 AAZ35722.1 - 1.4e-47 161.8 4.4 1.4e-47 161.8 4.4 1.4 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ35722.1 - 1.7e-18 66.3 0.1 3.2e-18 65.4 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AAZ35722.1 - 0.0063 16.3 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_AsnC-type PF13404.6 AAZ35722.1 - 0.038 13.8 0.0 0.62 9.9 0.0 2.4 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_1 PF00126.27 AAZ35723.1 - 5e-17 61.6 0.0 8.6e-17 60.8 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family LNP1 PF15419.6 AAZ35723.1 - 0.00099 19.4 0.0 0.0012 19.1 0.0 1.1 1 0 0 1 1 1 1 Leukemia NUP98 fusion partner 1 HTH_Tnp_4 PF13613.6 AAZ35723.1 - 0.0013 18.4 0.0 0.0023 17.6 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_28 PF13518.6 AAZ35723.1 - 0.0025 17.9 0.0 0.0037 17.3 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_20 PF12840.7 AAZ35723.1 - 0.044 13.8 0.0 0.11 12.5 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Mga PF08280.11 AAZ35723.1 - 0.058 13.4 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain Cro PF09048.10 AAZ35723.1 - 0.088 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Cro VirD1 PF07328.11 AAZ35723.1 - 0.13 12.3 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 T-DNA border endonuclease VirD1 NUMOD1 PF07453.13 AAZ35723.1 - 0.14 12.5 0.1 0.23 11.8 0.1 1.3 1 0 0 1 1 1 0 NUMOD1 domain HTH_Tnp_ISL3 PF13542.6 AAZ35723.1 - 0.14 11.6 0.0 0.32 10.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 tRNA-synt_2c PF01411.19 AAZ35724.1 - 1.1e-223 743.7 0.0 1.5e-223 743.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) DHHA1 PF02272.19 AAZ35724.1 - 4.1e-26 92.1 6.1 9.9e-26 90.8 6.1 1.7 1 0 0 1 1 1 1 DHHA1 domain tRNA_SAD PF07973.14 AAZ35724.1 - 5.9e-16 58.3 0.3 1.8e-15 56.8 0.3 1.9 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DUF1319 PF07028.11 AAZ35724.1 - 0.047 13.9 0.4 0.13 12.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1319) FAM92 PF06730.11 AAZ35724.1 - 0.13 11.7 0.9 0.25 10.7 0.9 1.4 1 0 0 1 1 1 0 FAM92 protein OmpA PF00691.20 AAZ35725.1 - 2e-24 85.8 0.8 4.4e-24 84.7 0.1 1.9 2 0 0 2 2 2 1 OmpA family DUF4398 PF14346.6 AAZ35725.1 - 6.6e-11 42.7 1.0 6.6e-11 42.7 1.0 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4398) Pilus_CpaD PF09476.10 AAZ35725.1 - 0.0096 15.7 0.3 0.036 13.8 0.1 2.0 2 0 0 2 2 2 1 Pilus biogenesis CpaD protein (pilus_cpaD) MRP-S28 PF10213.9 AAZ35725.1 - 0.16 12.4 0.1 0.54 10.7 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial ribosomal subunit protein Peptidase_S13 PF02113.15 AAZ35726.1 - 2e-82 277.3 0.1 2.6e-82 276.9 0.1 1.0 1 0 0 1 1 1 1 D-Ala-D-Ala carboxypeptidase 3 (S13) family Beta-lactamase2 PF13354.6 AAZ35726.1 - 0.0012 18.4 0.2 0.14 11.7 0.1 2.3 2 0 0 2 2 2 2 Beta-lactamase enzyme family DUF2997 PF11211.8 AAZ35726.1 - 0.02 14.7 0.1 0.053 13.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2997) Peptidase_S11 PF00768.20 AAZ35726.1 - 0.026 14.0 0.1 4.7 6.6 0.0 2.2 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase SdpA PF17418.2 AAZ35726.1 - 0.089 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Sporulation delaying protein SdpA IQ PF00612.27 AAZ35726.1 - 2.5 8.1 5.2 8.8 6.4 0.5 2.6 2 0 0 2 2 2 0 IQ calmodulin-binding motif DeoRC PF00455.22 AAZ35727.1 - 3.9e-45 153.6 0.4 6.7e-45 152.9 0.4 1.4 1 0 0 1 1 1 1 DeoR C terminal sensor domain HTH_DeoR PF08220.12 AAZ35727.1 - 1.4e-13 50.3 1.1 3e-13 49.3 1.1 1.6 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 AAZ35727.1 - 6.1e-09 35.7 0.1 1.2e-08 34.7 0.1 1.5 1 0 0 1 1 1 1 HTH domain GntR PF00392.21 AAZ35727.1 - 6.9e-06 25.6 0.1 1.9e-05 24.2 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_5 PF01022.20 AAZ35727.1 - 0.0089 15.9 0.5 0.018 14.9 0.5 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family Replic_Relax PF13814.6 AAZ35727.1 - 0.0099 16.0 0.1 0.021 14.9 0.1 1.6 1 0 0 1 1 1 1 Replication-relaxation HTH_23 PF13384.6 AAZ35727.1 - 0.022 14.6 0.1 0.052 13.4 0.1 1.7 1 0 0 1 1 1 0 Homeodomain-like domain MarR PF01047.22 AAZ35727.1 - 0.03 14.3 0.1 0.099 12.6 0.1 1.9 2 0 0 2 2 2 0 MarR family GD_AH_C PF04295.13 AAZ35728.1 - 9.3e-145 482.3 0.0 1.1e-144 482.1 0.0 1.0 1 0 0 1 1 1 1 D-galactarate dehydratase / Altronate hydrolase, C terminus SAF PF08666.12 AAZ35728.1 - 1.9e-11 44.4 0.2 3.9e-11 43.4 0.2 1.6 1 0 0 1 1 1 1 SAF domain Reprolysin_4 PF13583.6 AAZ35729.1 - 2e-05 24.3 0.4 2.7e-05 23.9 0.4 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 AAZ35729.1 - 8.6e-05 22.8 0.3 0.0001 22.5 0.3 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 AAZ35729.1 - 0.0001 22.3 0.1 0.00014 21.8 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 AAZ35729.1 - 0.0029 18.1 1.2 0.004 17.7 1.2 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 AAZ35729.1 - 0.05 12.6 0.3 0.065 12.2 0.3 1.2 1 0 0 1 1 1 0 Peptidase M66 NfrA_C PF13283.6 AAZ35730.1 - 8.6e-73 243.5 0.8 1.8e-72 242.4 0.8 1.6 1 0 0 1 1 1 1 Bacteriophage N adsorption protein A C-term TPR_16 PF13432.6 AAZ35730.1 - 2.8e-09 37.5 53.5 0.003 18.2 6.5 6.4 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 AAZ35730.1 - 9.5e-09 34.7 38.4 0.0075 16.3 0.2 8.4 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 AAZ35730.1 - 3e-07 30.7 47.8 0.0029 18.3 1.5 9.4 5 2 5 10 10 9 4 Tetratricopeptide repeat TPR_19 PF14559.6 AAZ35730.1 - 2.2e-05 24.8 14.9 0.00091 19.7 3.3 5.6 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 AAZ35730.1 - 9.6e-05 22.5 1.9 9.6e-05 22.5 1.9 4.1 5 1 0 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 AAZ35730.1 - 0.00072 19.8 30.6 0.00098 19.4 4.8 5.9 5 1 0 5 5 5 2 Tetratricopeptide repeat DUF2989 PF11207.8 AAZ35730.1 - 0.024 14.4 0.0 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2989) TPR_17 PF13431.6 AAZ35730.1 - 0.025 14.9 12.9 0.26 11.7 0.1 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF2379 PF09543.10 AAZ35730.1 - 0.086 13.0 0.1 0.086 13.0 0.1 3.6 5 0 0 5 5 5 0 Protein of unknown function (DUF2379) TPR_1 PF00515.28 AAZ35730.1 - 0.15 11.9 26.6 1.2 9.1 0.1 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 AAZ35730.1 - 0.29 11.4 11.1 4.8 7.5 0.2 4.0 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 AAZ35730.1 - 0.54 10.7 15.4 0.18 12.3 4.1 3.8 1 1 2 3 3 3 0 Bacterial transcriptional activator domain Wzy_C_2 PF11846.8 AAZ35730.1 - 0.55 10.1 13.1 2 8.3 1.2 3.9 2 1 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal OMP_b-brl PF13505.6 AAZ35730.1 - 1.4 9.0 7.0 0.4 10.8 2.4 2.1 1 1 1 2 2 2 0 Outer membrane protein beta-barrel domain TPR_8 PF13181.6 AAZ35730.1 - 1.8 9.0 18.7 2.9 8.3 0.1 6.2 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_7 PF13176.6 AAZ35730.1 - 7.4 6.8 13.8 22 5.4 0.1 5.8 5 1 0 5 5 5 0 Tetratricopeptide repeat ATP-synt_C PF00137.21 AAZ35731.1 - 2.9e-09 37.1 11.4 3.9e-09 36.7 11.4 1.2 1 0 0 1 1 1 1 ATP synthase subunit C BPD_transp_2 PF02653.16 AAZ35732.1 - 7.2e-31 107.3 17.8 7.2e-31 107.3 17.8 1.4 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component Gp5_C PF06715.12 AAZ35732.1 - 0.00016 21.6 0.1 0.00063 19.7 0.1 2.0 2 0 0 2 2 2 1 Gp5 C-terminal repeat (3 copies) DUF1427 PF07235.11 AAZ35732.1 - 0.00037 20.4 3.8 0.00087 19.2 3.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1427) ABC2_membrane PF01061.24 AAZ35733.1 - 2.5e-39 134.9 24.2 2.5e-39 134.9 24.2 1.7 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 AAZ35733.1 - 8.1e-09 35.0 27.4 8.1e-09 35.0 27.4 1.5 1 1 1 2 2 2 1 ABC-2 family transporter protein CcmB PF03379.13 AAZ35733.1 - 0.14 11.6 8.8 0.12 11.9 7.7 1.6 1 1 0 1 1 1 0 CcmB protein ALAD PF00490.21 AAZ35734.1 - 3.9e-135 450.1 0.0 4.4e-135 449.9 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase CheW PF01584.19 AAZ35735.1 - 2.9e-27 95.0 0.0 3.7e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 CheW-like domain Band_7 PF01145.25 AAZ35736.1 - 1.3e-28 100.2 4.3 1.3e-28 100.2 4.3 1.8 1 1 1 2 2 2 1 SPFH domain / Band 7 family DUF5134 PF17197.4 AAZ35736.1 - 0.022 14.6 0.6 0.043 13.7 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5134) BCAS2 PF05700.11 AAZ35736.1 - 0.025 14.3 1.4 0.044 13.5 1.4 1.3 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) PAS_4 PF08448.10 AAZ35737.1 - 8.2e-26 90.4 0.3 3.5e-16 59.4 0.0 2.5 2 0 0 2 2 2 2 PAS fold HATPase_c PF02518.26 AAZ35737.1 - 1.8e-19 70.3 0.0 3.7e-19 69.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AAZ35737.1 - 1.2e-15 57.6 0.0 2.5e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 AAZ35737.1 - 5e-08 32.9 1.6 7.8e-08 32.2 0.1 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HPTransfase PF10090.9 AAZ35737.1 - 0.00054 19.8 0.0 0.0016 18.2 0.0 1.8 1 0 0 1 1 1 1 Histidine phosphotransferase C-terminal domain HATPase_c_3 PF13589.6 AAZ35737.1 - 0.0036 17.1 0.0 0.0065 16.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.25 AAZ35737.1 - 0.01 15.8 0.0 0.12 12.4 0.0 2.7 1 1 1 2 2 2 0 PAS fold PAS_9 PF13426.7 AAZ35737.1 - 0.047 13.9 0.0 3 8.1 0.0 2.7 2 0 0 2 2 2 0 PAS domain PAS_8 PF13188.7 AAZ35737.1 - 0.07 13.2 0.0 2 8.5 0.0 2.8 2 0 0 2 2 2 0 PAS domain PAS_10 PF13596.6 AAZ35737.1 - 0.17 12.5 0.0 1.5 9.4 0.0 2.4 2 1 0 2 2 2 0 PAS domain YabA PF06156.13 AAZ35737.1 - 0.27 11.9 0.0 0.27 11.9 0.0 2.2 3 0 0 3 3 3 0 Initiation control protein YabA PEP-utilisers_N PF05524.13 AAZ35737.1 - 3.1 8.0 5.8 24 5.2 0.0 3.3 3 0 0 3 3 3 0 PEP-utilising enzyme, N-terminal UvrD-helicase PF00580.21 AAZ35738.1 - 1.7e-73 247.9 0.9 1e-71 242.0 0.9 2.4 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 AAZ35738.1 - 2.2e-67 227.9 0.3 7.8e-67 226.1 0.3 1.8 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 AAZ35738.1 - 4.8e-34 117.8 0.0 9.6e-34 116.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 AAZ35738.1 - 6.5e-09 35.5 0.0 2.4e-08 33.7 0.0 1.9 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 AAZ35738.1 - 1.6e-07 31.2 0.0 2.9e-05 23.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 AAZ35738.1 - 4.8e-06 26.5 0.2 0.13 11.9 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.6 AAZ35738.1 - 0.0024 17.5 0.4 0.47 10.0 0.0 2.8 2 1 1 3 3 3 1 AAA domain DUF287 PF03384.14 AAZ35738.1 - 0.019 15.3 2.1 0.024 15.0 0.3 2.2 2 0 0 2 2 2 0 Drosophila protein of unknown function, DUF287 Abhydrolase_6 PF12697.7 AAZ35739.1 - 2.1e-13 51.4 8.9 2.7e-13 51.0 8.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAZ35739.1 - 0.00026 20.4 0.0 0.00047 19.5 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 AAZ35739.1 - 0.003 17.3 0.0 0.0031 17.2 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Ser_hydrolase PF06821.13 AAZ35739.1 - 0.0046 16.8 0.1 0.0093 15.8 0.0 1.5 2 0 0 2 2 2 1 Serine hydrolase Abhydrolase_1 PF00561.20 AAZ35739.1 - 0.029 14.0 0.0 0.076 12.7 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Thioesterase PF00975.20 AAZ35739.1 - 0.06 13.5 0.0 0.13 12.4 0.1 1.5 2 0 0 2 2 2 0 Thioesterase domain Abhydrolase_2 PF02230.16 AAZ35739.1 - 0.095 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Trans_reg_C PF00486.28 AAZ35740.1 - 3.5e-14 52.6 0.1 9.6e-13 48.0 0.0 3.0 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal AAA_22 PF13401.6 AAZ35740.1 - 1.3e-08 35.2 0.0 7.5e-08 32.7 0.0 2.3 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 AAZ35740.1 - 9.1e-06 26.2 1.5 0.00018 21.9 0.2 2.8 1 1 1 2 2 2 1 AAA ATPase domain CbiA PF01656.23 AAZ35740.1 - 0.00012 22.1 0.0 0.00018 21.6 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.6 AAZ35740.1 - 0.00053 19.6 0.3 0.0029 17.2 0.2 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 AAZ35740.1 - 0.002 18.5 0.0 0.0055 17.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 AAZ35740.1 - 0.0079 15.4 0.0 0.018 14.2 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain AAA_5 PF07728.14 AAZ35740.1 - 0.0093 16.0 0.0 0.26 11.3 0.0 2.8 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) ArsA_ATPase PF02374.15 AAZ35740.1 - 0.0094 15.2 0.1 0.02 14.1 0.1 1.5 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_18 PF13238.6 AAZ35740.1 - 0.011 16.3 0.0 0.052 14.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain ParA PF10609.9 AAZ35740.1 - 0.011 15.1 0.1 0.022 14.2 0.1 1.4 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase IstB_IS21 PF01695.17 AAZ35740.1 - 0.015 15.1 0.0 0.04 13.6 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 AAZ35740.1 - 0.022 14.7 0.1 0.072 13.0 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_31 PF13614.6 AAZ35740.1 - 0.037 14.0 0.1 0.074 13.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 AAZ35740.1 - 0.12 12.3 0.1 0.64 9.9 0.1 2.1 2 0 0 2 2 2 0 NTPase AAA_14 PF13173.6 AAZ35740.1 - 0.13 12.3 0.0 0.31 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 AAZ35740.1 - 0.13 12.5 0.2 9.8 6.4 0.2 2.8 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 AAZ35740.1 - 0.18 11.7 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain Chorismate_bind PF00425.18 AAZ35741.1 - 7.1e-74 248.6 0.0 9.7e-74 248.2 0.0 1.1 1 0 0 1 1 1 1 chorismate binding enzyme Pept_tRNA_hydro PF01195.19 AAZ35742.1 - 5e-54 182.8 0.0 5.7e-54 182.6 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase DUF1652 PF07865.11 AAZ35743.1 - 9.7e-21 73.4 0.2 1.4e-20 72.9 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1652) BPD_transp_1 PF00528.22 AAZ35744.1 - 9.1e-15 54.9 17.8 9.1e-15 54.9 17.8 2.0 1 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component CCSMST1 PF15013.6 AAZ35744.1 - 0.00054 20.1 0.0 0.0014 18.7 0.0 1.7 1 0 0 1 1 1 1 CCSMST1 family DUF3817 PF12823.7 AAZ35744.1 - 0.089 13.6 0.3 0.089 13.6 0.3 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF3817) Polysacc_deac_1 PF01522.21 AAZ35745.1 - 9.2e-20 70.8 0.1 3.7e-19 68.8 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide deacetylase DUF2334 PF10096.9 AAZ35745.1 - 8.1e-07 28.9 0.2 1.9e-06 27.7 0.1 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 AAZ35745.1 - 0.04 12.3 0.1 0.052 11.9 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) DUF563 PF04577.14 AAZ35745.1 - 0.052 13.7 0.1 2 8.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF563) SelR PF01641.18 AAZ35748.1 - 4.4e-56 188.2 0.0 4.9e-56 188.0 0.0 1.0 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.14 AAZ35748.1 - 8.9e-05 22.7 0.2 0.00017 21.7 0.2 1.5 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_10 PF10058.9 AAZ35748.1 - 0.1 12.4 2.5 1 9.1 0.0 2.3 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein HECT_2 PF09814.9 AAZ35748.1 - 0.18 10.6 0.8 4.9 5.9 0.0 2.1 2 0 0 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding DUF21 PF01595.20 AAZ35749.1 - 2.6e-17 63.1 1.0 4.2e-17 62.4 1.0 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CorC_HlyC PF03471.17 AAZ35749.1 - 3.2e-16 59.1 0.0 7.6e-16 57.9 0.0 1.6 1 0 0 1 1 1 1 Transporter associated domain CBS PF00571.28 AAZ35749.1 - 1.6e-10 41.2 0.9 3.4e-06 27.4 0.0 2.7 2 0 0 2 2 2 2 CBS domain Iso_dh PF00180.20 AAZ35750.1 - 3.9e-76 256.5 0.0 4.9e-76 256.1 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase MnmE_helical PF12631.7 AAZ35751.1 - 6.4e-58 196.3 0.8 7.9e-58 196.0 0.8 1.1 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 AAZ35751.1 - 1.9e-38 131.3 0.0 4.3e-38 130.2 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 AAZ35751.1 - 1.5e-23 83.0 0.0 3.1e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AAZ35751.1 - 2.7e-09 36.7 0.0 4.7e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 AAZ35751.1 - 1.2e-06 28.7 0.3 0.00049 20.2 0.0 2.4 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.16 AAZ35751.1 - 1.1e-05 24.8 0.0 1.7e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 AIG1 family Ras PF00071.22 AAZ35751.1 - 0.00023 20.8 0.0 0.00049 19.7 0.0 1.5 2 0 0 2 2 2 1 Ras family RsgA_GTPase PF03193.16 AAZ35751.1 - 0.00063 19.7 0.0 0.002 18.0 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 AAZ35751.1 - 0.0019 18.7 0.0 0.0039 17.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_28 PF13521.6 AAZ35751.1 - 0.003 17.8 0.2 0.0063 16.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 AAZ35751.1 - 0.0061 16.8 0.0 0.012 15.8 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 AAZ35751.1 - 0.057 12.8 0.0 0.091 12.1 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_18 PF13238.6 AAZ35751.1 - 0.18 12.3 0.0 0.59 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 AAZ35751.1 - 0.61 10.5 4.8 0.77 10.1 0.9 2.9 2 1 0 2 2 2 0 AAA ATPase domain DUF4096 PF13340.6 AAZ35752.1 - 5.8e-25 87.3 0.4 1.5e-24 86.0 0.4 1.8 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1 PF01609.21 AAZ35752.1 - 3.2e-14 53.1 0.0 5.7e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AAZ35752.1 - 7.2e-10 39.1 0.2 2.1e-09 37.6 0.2 1.9 1 0 0 1 1 1 1 Transposase DDE domain HTH_Tnp_Tc3_2 PF01498.18 AAZ35752.1 - 0.061 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Transposase DUF1275 PF06912.11 AAZ35753.1 - 2.4e-32 112.5 22.7 2.7e-32 112.2 22.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) MIP PF00230.20 AAZ35753.1 - 0.025 14.3 1.7 0.025 14.3 1.7 2.2 1 1 0 2 2 2 0 Major intrinsic protein MFS_1 PF07690.16 AAZ35753.1 - 2 7.2 26.9 0.53 9.2 17.0 2.3 1 1 1 2 2 2 0 Major Facilitator Superfamily LysR_substrate PF03466.20 AAZ35754.1 - 2.6e-36 125.0 0.1 3.7e-36 124.5 0.1 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ35754.1 - 7.9e-13 48.2 0.3 1.5e-12 47.2 0.3 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family adh_short PF00106.25 AAZ35755.1 - 1.3e-48 165.1 0.0 1.6e-48 164.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAZ35755.1 - 2.3e-36 125.5 0.0 2.8e-36 125.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAZ35755.1 - 1.1e-15 58.1 0.0 1.4e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 AAZ35755.1 - 4.5e-05 22.7 0.0 0.00041 19.6 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 AAZ35755.1 - 0.022 14.7 0.0 0.05 13.5 0.1 1.5 2 0 0 2 2 2 0 NAD(P)H-binding Epimerase PF01370.21 AAZ35755.1 - 0.033 13.7 0.0 0.073 12.5 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Phage_tail_APC PF16778.5 AAZ35756.1 - 0.0086 15.9 4.0 0.02 14.7 4.0 1.9 1 1 0 1 1 1 1 Phage tail assembly chaperone protein Glycos_transf_1 PF00534.20 AAZ35757.1 - 4.9e-13 49.0 0.0 7.8e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAZ35757.1 - 1.9e-11 44.5 0.0 3.8e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAZ35757.1 - 1.5e-05 25.1 0.3 2.5e-05 24.3 0.3 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AAZ35757.1 - 0.00021 21.8 1.8 0.0006 20.3 1.8 1.8 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain CSD PF00313.22 AAZ35758.1 - 3e-28 97.4 1.5 3.3e-28 97.3 1.5 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 AAZ35758.1 - 0.0017 18.0 0.1 0.0032 17.1 0.1 1.5 1 0 0 1 1 1 1 Ribonuclease B OB domain CusF_Ec PF11604.8 AAZ35758.1 - 0.035 14.1 0.2 0.052 13.5 0.2 1.3 1 0 0 1 1 1 0 Copper binding periplasmic protein CusF BPD_transp_2 PF02653.16 AAZ35759.1 - 3.4e-55 187.1 42.5 2.9e-54 184.0 33.0 2.1 2 0 0 2 2 2 2 Branched-chain amino acid transport system / permease component DUF3382 PF11862.8 AAZ35759.1 - 1.9e-16 60.1 4.4 1.9e-16 60.1 4.4 4.7 5 1 0 5 5 5 1 Domain of unknown function (DUF3382) EamA PF00892.20 AAZ35760.1 - 1.1e-31 109.8 34.2 4.4e-18 65.8 12.4 2.0 2 0 0 2 2 2 2 EamA-like transporter family DUF4131 PF13567.6 AAZ35760.1 - 0.77 9.4 6.0 2.3 7.9 4.7 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Rhodanese PF00581.20 AAZ35761.1 - 7.7e-07 29.6 0.1 1e-06 29.2 0.1 1.1 1 0 0 1 1 1 1 Rhodanese-like domain FTR1 PF03239.14 AAZ35762.1 - 4.3e-24 85.2 29.9 2.5e-15 56.5 18.4 1.9 1 1 1 2 2 2 2 Iron permease FTR1 family Cytochrome_CBB3 PF13442.6 AAZ35762.1 - 1.1e-12 48.1 0.0 2.6e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AAZ35762.1 - 2e-09 38.5 0.0 6.3e-09 36.9 0.0 2.0 1 0 0 1 1 1 1 Cytochrome c DUF2058 PF09831.9 AAZ35763.1 - 2.8e-61 206.7 12.0 3.1e-61 206.5 12.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2058) DUF2161 PF09929.9 AAZ35763.1 - 0.056 13.6 3.9 0.083 13.0 3.9 1.2 1 0 0 1 1 1 0 Putative PD-(D/E)XK phosphodiesterase (DUF2161) MMU163 PF17119.5 AAZ35763.1 - 0.28 10.3 3.3 0.35 10.0 3.3 1.1 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis DUF3492 PF11997.8 AAZ35763.1 - 0.46 10.2 3.0 0.59 9.8 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) CRA PF06589.11 AAZ35763.1 - 0.63 10.1 6.5 0.84 9.7 6.5 1.1 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) FAM60A PF15396.6 AAZ35763.1 - 0.98 9.4 5.9 1.2 9.1 5.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Presenilin PF01080.17 AAZ35763.1 - 3.9 6.1 6.5 4.5 5.9 6.5 1.0 1 0 0 1 1 1 0 Presenilin BPD_transp_1 PF00528.22 AAZ35764.1 - 5.1e-17 62.2 19.3 5.1e-17 62.2 19.3 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component SPC25 PF06703.11 AAZ35764.1 - 9.6 6.0 9.5 1.2 8.9 1.6 2.2 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Peptidase_M23 PF01551.22 AAZ35765.1 - 2.6e-25 88.5 0.2 6.4e-25 87.2 0.2 1.7 1 0 0 1 1 1 1 Peptidase family M23 CENP-F_leu_zip PF10473.9 AAZ35765.1 - 0.0025 17.9 16.2 0.0025 17.9 16.2 2.4 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 AAZ35765.1 - 0.0041 17.7 16.0 0.0041 17.7 16.0 3.2 1 1 2 3 3 2 2 Apg6 coiled-coil region DUF3450 PF11932.8 AAZ35765.1 - 0.0082 15.5 10.6 0.0082 15.5 10.6 2.7 2 1 0 2 2 1 1 Protein of unknown function (DUF3450) zf-C4H2 PF10146.9 AAZ35765.1 - 0.012 16.0 20.6 0.23 11.8 5.2 2.1 2 0 0 2 2 2 0 Zinc finger-containing protein Cep57_CLD_2 PF14197.6 AAZ35765.1 - 0.023 14.8 3.6 0.023 14.8 3.6 4.7 3 1 1 4 4 3 0 Centrosome localisation domain of PPC89 IFT57 PF10498.9 AAZ35765.1 - 0.32 9.9 31.1 0.45 9.4 13.9 2.5 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 GAS PF13851.6 AAZ35765.1 - 1.4 8.3 45.4 0.1 11.9 14.4 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding FapA PF03961.13 AAZ35765.1 - 1.7 7.2 26.3 0.12 11.0 7.9 2.2 2 0 0 2 2 2 0 Flagellar Assembly Protein A DUF1664 PF07889.12 AAZ35765.1 - 2.1 8.4 21.9 2.5 8.2 6.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 AAZ35765.1 - 2.2 7.1 44.4 0.44 9.4 12.8 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF812 PF05667.11 AAZ35765.1 - 2.9 6.7 39.4 0.29 10.0 11.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Histone_HNS PF00816.21 AAZ35766.1 - 0.00087 20.1 2.1 0.0013 19.5 2.1 1.4 1 1 0 1 1 1 1 H-NS histone family Cnd1_N PF12922.7 AAZ35766.1 - 0.011 15.6 0.1 0.012 15.5 0.1 1.2 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term Allexi_40kDa PF05549.11 AAZ35766.1 - 0.12 11.8 0.2 0.13 11.8 0.2 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein FUSC PF04632.12 AAZ35767.1 - 1.7e-16 59.9 7.2 2.5e-16 59.4 7.2 1.2 1 0 0 1 1 1 1 Fusaric acid resistance protein family FUSC_2 PF13515.6 AAZ35767.1 - 1.3e-12 47.9 11.3 2e-12 47.3 11.3 1.3 1 0 0 1 1 1 1 Fusaric acid resistance protein-like ArAE_1 PF06081.11 AAZ35767.1 - 0.022 14.9 3.6 0.093 12.9 3.6 2.0 1 1 0 1 1 1 0 Aromatic acid exporter family member 1 DUF2955 PF11168.8 AAZ35767.1 - 0.65 9.9 8.0 1.3 8.9 7.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2955) DUF2231 PF09990.9 AAZ35768.1 - 0.015 15.8 11.7 0.074 13.5 11.7 1.9 1 1 0 1 1 1 0 Predicted membrane protein (DUF2231) DUF4507 PF14964.6 AAZ35768.1 - 0.12 11.3 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4507) Hum_adeno_E3A PF05393.11 AAZ35768.1 - 0.13 12.3 0.6 0.26 11.3 0.1 1.7 1 1 0 2 2 2 0 Human adenovirus early E3A glycoprotein TssN PF17555.2 AAZ35768.1 - 0.26 10.6 2.3 0.23 10.8 0.9 1.5 1 1 0 1 1 1 0 Type VI secretion system, TssN DUF1129 PF06570.11 AAZ35768.1 - 0.28 10.6 2.6 0.28 10.6 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) LrgA PF03788.14 AAZ35768.1 - 0.34 10.9 6.3 0.33 10.9 4.9 1.7 1 1 1 2 2 2 0 LrgA family DUF202 PF02656.15 AAZ35768.1 - 2.3 8.7 15.5 2.5 8.6 3.6 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF202) NUDIX PF00293.28 AAZ35769.1 - 4.4e-19 68.8 0.0 6.9e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.11 AAZ35769.1 - 6.3e-10 38.5 1.9 1.1e-09 37.7 1.9 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain NUDIX-like PF09296.11 AAZ35769.1 - 1.9e-07 31.6 0.1 6e-07 30.1 0.1 1.8 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain GCV_T PF01571.21 AAZ35770.1 - 6.3e-73 245.3 0.1 9.6e-73 244.7 0.1 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain SO_alpha_A3 PF17806.1 AAZ35770.1 - 8.9e-30 102.9 0.1 2.1e-29 101.7 0.1 1.6 1 0 0 1 1 1 1 Sarcosine oxidase A3 domain Fer2_4 PF13510.6 AAZ35770.1 - 1.4e-23 82.8 0.0 1.4e-22 79.5 0.0 2.8 3 0 0 3 3 2 1 2Fe-2S iron-sulfur cluster binding domain GCV_T_C PF08669.11 AAZ35770.1 - 5.8e-19 67.8 0.0 1.8e-18 66.2 0.0 1.9 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Pyr_redox_2 PF07992.14 AAZ35770.1 - 9.8e-15 54.5 0.2 1.6e-14 53.9 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AAZ35770.1 - 3.4e-12 46.4 0.3 6.6e-12 45.5 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 AAZ35770.1 - 2e-08 33.8 0.1 0.00063 19.1 0.5 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AAZ35770.1 - 4.7e-08 32.5 1.0 4.7e-08 32.5 1.0 2.4 2 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 AAZ35770.1 - 5.3e-08 33.0 0.4 3.8e-07 30.3 0.3 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 AAZ35770.1 - 6.3e-07 28.4 0.3 9.8e-07 27.8 0.3 1.3 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 AAZ35770.1 - 2.6e-06 26.8 1.4 1.1e-05 24.7 1.2 1.8 1 1 1 2 2 2 1 Glucose inhibited division protein A DAO PF01266.24 AAZ35770.1 - 8.7e-05 22.3 1.0 0.0004 20.1 0.1 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 AAZ35770.1 - 0.00017 20.9 0.1 0.00036 19.9 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 AAZ35770.1 - 0.00072 18.9 1.3 0.0017 17.7 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 AAZ35770.1 - 0.0016 19.0 0.4 0.032 14.8 0.1 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 AAZ35770.1 - 0.0026 16.9 0.1 0.0045 16.1 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 AAZ35770.1 - 0.0073 15.6 0.3 0.017 14.4 0.3 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 AAZ35770.1 - 0.088 12.7 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SCP2 PF02036.17 AAZ35771.1 - 1.4e-15 57.6 0.0 2.2e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 SCP-2 sterol transfer family MDMPI_C PF07398.11 AAZ35771.1 - 0.00021 22.1 0.7 0.00087 20.1 0.7 2.0 1 1 0 1 1 1 1 MDMPI C-terminal domain Alkyl_sulf_C PF14864.6 AAZ35771.1 - 0.0099 16.1 0.0 0.017 15.4 0.0 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Acetyltransf_1 PF00583.25 AAZ35772.1 - 2.1e-11 44.1 0.0 2.7e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAZ35772.1 - 1.5e-08 34.9 0.0 2.2e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAZ35772.1 - 1.6e-07 31.3 0.0 1.8e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AAZ35772.1 - 1.5e-05 25.1 0.0 2.5e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAZ35772.1 - 0.012 15.6 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.6 AAZ35772.1 - 0.096 12.8 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PanZ PF12568.8 AAZ35772.1 - 0.13 12.0 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Aminotran_1_2 PF00155.21 AAZ35773.1 - 4.7e-56 190.5 0.0 5.3e-56 190.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 AAZ35773.1 - 6.6e-05 21.6 0.0 0.00013 20.6 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 AAZ35773.1 - 0.00062 19.2 2.1 0.0046 16.3 2.1 2.2 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 AAZ35773.1 - 0.0035 16.6 0.0 0.013 14.8 0.0 1.9 1 1 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.20 AAZ35773.1 - 0.0084 14.9 0.0 0.036 12.8 0.0 1.8 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Aminotran_5 PF00266.19 AAZ35773.1 - 0.086 11.8 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Leu_Phe_trans PF03588.14 AAZ35774.1 - 7.9e-77 256.5 0.0 9.3e-77 256.3 0.0 1.0 1 0 0 1 1 1 1 Leucyl/phenylalanyl-tRNA protein transferase Y1_Tnp PF01797.16 AAZ35775.1 - 5.5e-14 52.3 0.0 7e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Transposase IS200 like Oxidored_FMN PF00724.20 AAZ35775.1 - 0.088 12.1 0.0 0.097 11.9 0.0 1.1 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family Phage_tail_X PF05489.12 AAZ35776.1 - 3.5e-19 68.2 0.1 4.5e-19 67.9 0.1 1.1 1 0 0 1 1 1 1 Phage Tail Protein X DUF1547 PF07577.11 AAZ35776.1 - 0.0054 17.1 0.0 0.0073 16.7 0.0 1.2 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1547) Methyltransf_25 PF13649.6 AAZ35777.1 - 8.4e-17 61.7 0.0 1.3e-16 61.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAZ35777.1 - 5.9e-16 58.9 0.0 9.9e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAZ35777.1 - 5.4e-15 55.6 0.0 9.1e-15 54.9 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAZ35777.1 - 1.9e-10 40.7 0.0 2.6e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAZ35777.1 - 2.4e-09 37.8 0.0 4.1e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 AAZ35777.1 - 0.00026 20.7 0.0 0.0068 16.1 0.0 2.1 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) CheR PF01739.18 AAZ35777.1 - 0.0017 17.9 0.0 0.044 13.3 0.0 2.1 1 1 0 2 2 2 1 CheR methyltransferase, SAM binding domain Ubie_methyltran PF01209.18 AAZ35777.1 - 0.0046 16.3 0.0 0.33 10.2 0.0 2.3 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family TehB PF03848.14 AAZ35777.1 - 0.016 14.7 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_9 PF08003.11 AAZ35777.1 - 0.044 12.7 0.0 0.061 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) DUF481 PF04338.12 AAZ35778.1 - 3.7e-48 164.4 10.2 4.4e-48 164.1 10.2 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF481 SH3_19 PF18597.1 AAZ35778.1 - 0.00045 20.0 0.3 0.002 17.9 0.0 2.2 3 0 0 3 3 3 1 Myosin X N-terminal SH3 domain Hfq PF17209.3 AAZ35778.1 - 0.025 14.2 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 Hfq protein OMP_b-brl PF13505.6 AAZ35778.1 - 2.8 8.0 9.0 15 5.7 9.0 2.3 1 1 0 1 1 1 0 Outer membrane protein beta-barrel domain Peptidase_S24 PF00717.23 AAZ35779.1 - 3.8e-08 33.2 0.1 1.6e-07 31.1 0.0 1.9 2 0 0 2 2 2 1 Peptidase S24-like YdaS_antitoxin PF15943.5 AAZ35779.1 - 0.0036 17.1 0.0 0.0087 15.9 0.0 1.6 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Abhydrolase_3 PF07859.13 AAZ35780.1 - 3.9e-21 75.9 0.6 7.8e-18 65.1 1.3 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 AAZ35780.1 - 6.9e-20 71.4 0.3 9.2e-19 67.7 0.3 2.0 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 AAZ35780.1 - 2.6e-09 36.9 0.1 0.0047 16.4 0.0 3.0 3 0 0 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 AAZ35780.1 - 0.00044 20.9 3.3 0.00063 20.4 3.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 AAZ35780.1 - 0.0026 16.7 0.0 0.0038 16.2 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 AAZ35780.1 - 0.0089 15.3 0.3 0.18 11.0 0.3 2.6 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AAZ35780.1 - 0.055 13.1 0.2 2.8 7.5 0.3 2.3 1 1 0 2 2 2 0 alpha/beta hydrolase fold adh_short PF00106.25 AAZ35781.1 - 3.2e-46 157.3 0.0 3.8e-46 157.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAZ35781.1 - 2.1e-28 99.5 0.0 2.7e-28 99.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAZ35781.1 - 2.7e-10 40.5 0.0 3.8e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 AAZ35781.1 - 0.017 14.3 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Ion_trans PF00520.31 AAZ35782.1 - 4.3e-25 88.4 11.1 5e-25 88.1 11.1 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 AAZ35782.1 - 1.1e-14 54.2 6.6 1.1e-14 54.2 6.6 2.3 3 0 0 3 3 3 1 Ion channel NOB1_Zn_bind PF08772.11 AAZ35782.1 - 0.0083 16.3 1.2 0.014 15.5 1.2 1.3 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like DZR PF12773.7 AAZ35782.1 - 0.023 14.7 1.0 0.038 14.0 1.0 1.3 1 0 0 1 1 1 0 Double zinc ribbon TF_Zn_Ribbon PF08271.12 AAZ35782.1 - 0.075 12.6 1.0 0.15 11.6 1.0 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Rad50_zn_hook PF04423.14 AAZ35782.1 - 0.085 12.7 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Rad50 zinc hook motif DUF21 PF01595.20 AAZ35782.1 - 0.15 11.8 10.7 0.29 10.8 2.2 2.4 1 1 0 2 2 2 0 Cyclin M transmembrane N-terminal domain zinc_ribbon_2 PF13240.6 AAZ35782.1 - 0.47 10.2 2.2 1.2 8.9 2.2 1.7 1 1 0 1 1 1 0 zinc-ribbon domain GCV_H PF01597.19 AAZ35783.1 - 4.2e-42 142.9 0.0 4.6e-42 142.8 0.0 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 AAZ35783.1 - 0.0077 16.0 0.1 0.024 14.5 0.1 1.8 2 0 0 2 2 2 1 Biotin-requiring enzyme OHCU_decarbox PF09349.10 AAZ35784.1 - 2e-45 155.0 0.2 2.3e-45 154.9 0.2 1.0 1 0 0 1 1 1 1 OHCU decarboxylase RBFA PF02033.18 AAZ35785.1 - 1.3e-32 112.4 0.2 1.5e-32 112.2 0.2 1.1 1 0 0 1 1 1 1 Ribosome-binding factor A EPO_TPO PF00758.18 AAZ35785.1 - 0.06 13.4 0.0 0.075 13.1 0.0 1.1 1 0 0 1 1 1 0 Erythropoietin/thrombopoietin Dynein_attach_N PF15867.5 AAZ35785.1 - 0.095 12.7 0.0 0.62 10.1 0.0 2.1 2 0 0 2 2 2 0 Dynein attachment factor N-terminus NAD_binding_1 PF00175.21 AAZ35786.1 - 4.1e-13 49.9 0.0 6.2e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 AAZ35786.1 - 5.9e-08 33.0 0.0 1.1e-07 32.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 AAZ35786.1 - 0.00042 20.5 0.0 0.0079 16.3 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 AAZ35786.1 - 0.0054 16.8 0.0 0.0086 16.1 0.0 1.3 1 0 0 1 1 1 1 FAD-binding domain DUF905 PF06006.12 AAZ35786.1 - 0.023 14.6 0.1 0.19 11.8 0.1 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF905) Peptidase_S66C PF17676.1 AAZ35786.1 - 0.1 13.1 0.0 0.17 12.5 0.0 1.3 1 0 0 1 1 1 0 LD-carboxypeptidase C-terminal domain Methyltransf_11 PF08241.12 AAZ35787.1 - 5.2e-26 91.1 0.0 1.1e-25 90.1 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAZ35787.1 - 1.3e-22 80.3 0.0 2.1e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAZ35787.1 - 1.4e-21 76.9 0.0 1.7e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAZ35787.1 - 3.2e-14 53.5 0.0 1.4e-13 51.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAZ35787.1 - 7.6e-13 48.6 0.0 1e-12 48.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AAZ35787.1 - 9.1e-11 41.5 0.0 1.6e-10 40.7 0.0 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 AAZ35787.1 - 1.6e-06 27.8 0.0 2e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.15 AAZ35787.1 - 0.00011 22.1 0.0 0.00024 21.0 0.0 1.7 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_29 PF03141.16 AAZ35787.1 - 0.0025 16.4 0.0 0.0028 16.3 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase UPF0020 PF01170.18 AAZ35787.1 - 0.0049 16.6 0.0 0.0069 16.1 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_4 PF02390.17 AAZ35787.1 - 0.0064 16.0 0.0 1.6 8.2 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_24 PF13578.6 AAZ35787.1 - 0.0099 16.9 0.0 0.021 15.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 AAZ35787.1 - 0.014 14.9 0.0 0.06 12.8 0.0 1.9 1 1 0 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_17 PF12692.7 AAZ35787.1 - 0.015 15.3 0.0 0.047 13.7 0.0 1.7 2 0 0 2 2 2 0 S-adenosyl-L-methionine methyltransferase MetW PF07021.12 AAZ35787.1 - 0.017 14.7 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_2 PF00891.18 AAZ35787.1 - 0.035 13.4 0.0 0.052 12.8 0.0 1.3 1 1 0 1 1 1 0 O-methyltransferase domain NodS PF05401.11 AAZ35787.1 - 0.073 12.7 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_32 PF13679.6 AAZ35787.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_5 PF01795.19 AAZ35787.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 2 0 0 2 2 2 0 MraW methylase family LEA_2 PF03168.13 AAZ35788.1 - 2.2e-16 60.3 0.0 2.8e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Late embryogenesis abundant protein LPAM_1 PF08139.12 AAZ35788.1 - 0.0073 16.7 0.7 0.014 15.9 0.7 1.5 1 0 0 1 1 1 1 Prokaryotic membrane lipoprotein lipid attachment site Sigma54_activat PF00158.26 AAZ35789.1 - 7.1e-63 211.3 0.0 1.2e-62 210.6 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AAZ35789.1 - 1.7e-18 67.0 0.0 5.8e-18 65.4 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 AAZ35789.1 - 1.7e-08 34.1 1.2 3.5e-08 33.1 0.3 2.0 2 0 0 2 2 1 1 Bacterial regulatory protein, Fis family HTH_30 PF13556.6 AAZ35789.1 - 3.8e-06 26.6 0.1 9.5e-06 25.3 0.1 1.7 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain GAF PF01590.26 AAZ35789.1 - 1.5e-05 25.7 0.0 4.8e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 GAF domain HTH_7 PF02796.15 AAZ35789.1 - 0.00014 21.9 0.0 0.00039 20.4 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase AAA_5 PF07728.14 AAZ35789.1 - 0.0009 19.3 0.0 0.002 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 AAZ35789.1 - 0.00091 18.7 0.0 0.005 16.3 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA PF00004.29 AAZ35789.1 - 0.0019 18.6 0.0 0.0041 17.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) HTH_23 PF13384.6 AAZ35789.1 - 0.0048 16.6 0.0 0.014 15.2 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_11 PF08279.12 AAZ35789.1 - 0.007 16.3 0.0 0.019 14.9 0.0 1.7 1 0 0 1 1 1 1 HTH domain HTH_22 PF13309.6 AAZ35789.1 - 0.0071 16.4 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 HTH domain HTH_10 PF04967.12 AAZ35789.1 - 0.0077 16.0 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 HTH DNA binding domain HTH_20 PF12840.7 AAZ35789.1 - 0.0086 16.1 0.6 0.1 12.7 0.0 2.7 3 0 0 3 3 2 1 Helix-turn-helix domain HTH_28 PF13518.6 AAZ35789.1 - 0.0097 16.0 0.2 0.042 14.0 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 AAZ35789.1 - 0.014 15.4 0.1 0.032 14.3 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix PAS_4 PF08448.10 AAZ35789.1 - 0.014 15.6 0.0 8 6.8 0.0 3.1 3 0 0 3 3 2 0 PAS fold HTH_17 PF12728.7 AAZ35789.1 - 0.015 15.4 0.1 0.033 14.4 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_38 PF13936.6 AAZ35789.1 - 0.023 14.4 0.0 0.22 11.3 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_psq PF05225.16 AAZ35789.1 - 0.024 14.4 0.1 0.068 12.9 0.1 1.7 1 0 0 1 1 1 0 helix-turn-helix, Psq domain HTH_29 PF13551.6 AAZ35789.1 - 0.031 14.3 0.0 0.076 13.0 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix TetR_N PF00440.23 AAZ35789.1 - 0.07 12.9 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family PAS_7 PF12860.7 AAZ35789.1 - 0.083 13.1 0.0 0.24 11.6 0.0 1.8 1 0 0 1 1 1 0 PAS fold HTH_24 PF13412.6 AAZ35789.1 - 0.083 12.5 0.0 0.29 10.7 0.0 1.9 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding AAA_7 PF12775.7 AAZ35789.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region HTH_Tnp_1_2 PF13022.6 AAZ35789.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase AAA_30 PF13604.6 AAZ35789.1 - 0.14 11.9 0.0 0.47 10.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 AAZ35789.1 - 0.15 11.2 0.0 0.28 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) HTH_AsnC-type PF13404.6 AAZ35789.1 - 0.47 10.3 0.1 0.47 10.3 0.1 3.1 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain HTH_IclR PF09339.10 AAZ35789.1 - 0.69 9.8 2.6 3.6 7.5 0.0 3.3 4 0 0 4 4 3 0 IclR helix-turn-helix domain Fer4_20 PF14691.6 AAZ35791.1 - 4.9e-38 129.4 0.1 7.4e-38 128.8 0.1 1.2 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.14 AAZ35791.1 - 1.4e-25 90.2 0.0 1.8e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAZ35791.1 - 9.8e-12 44.7 0.6 2.2e-06 27.1 0.0 2.5 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAZ35791.1 - 1.1e-09 38.7 3.7 6.8e-06 26.6 0.2 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 AAZ35791.1 - 2.6e-07 29.4 0.1 0.00028 19.4 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 AAZ35791.1 - 4.3e-06 26.9 0.1 1.2e-05 25.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 AAZ35791.1 - 7.1e-05 22.3 0.2 0.0029 17.0 0.0 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 AAZ35791.1 - 9.9e-05 22.7 2.3 0.073 13.5 0.7 3.3 2 1 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 AAZ35791.1 - 0.00052 19.4 0.2 0.0009 18.6 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 AAZ35791.1 - 0.0008 18.2 1.1 0.00088 18.1 0.2 1.5 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 AAZ35791.1 - 0.00093 18.9 1.1 0.23 11.0 1.2 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 AAZ35791.1 - 0.0013 18.8 0.0 1.5 8.9 0.0 3.0 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 AAZ35791.1 - 0.0076 15.5 0.2 0.032 13.5 0.1 1.9 2 0 0 2 2 2 1 Thi4 family F420_oxidored PF03807.17 AAZ35791.1 - 0.018 15.6 0.1 8.5 7.0 0.0 3.3 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent FAD_binding_2 PF00890.24 AAZ35791.1 - 0.082 12.0 0.5 0.36 9.8 0.4 1.9 2 0 0 2 2 2 0 FAD binding domain AlaDh_PNT_C PF01262.21 AAZ35791.1 - 0.13 11.5 2.1 1.8 7.8 0.2 2.5 2 1 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 AAZ35791.1 - 0.15 12.0 0.0 0.35 10.7 0.0 1.7 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K_oxygenase PF13434.6 AAZ35791.1 - 0.16 11.1 0.0 13 4.8 0.0 2.8 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) AdoHcyase_NAD PF00670.21 AAZ35791.1 - 0.17 12.0 2.3 6.6 6.8 0.2 2.4 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_1 PF00175.21 AAZ35792.1 - 3.2e-12 47.0 0.0 5.4e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Fer2 PF00111.27 AAZ35792.1 - 1.8e-08 34.2 0.8 4.2e-08 33.0 0.8 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain TonB_dep_Rec PF00593.24 AAZ35793.1 - 1.7e-48 166.7 24.6 1.7e-48 166.7 24.6 2.1 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 AAZ35793.1 - 3.5e-17 62.9 0.3 1.1e-16 61.3 0.3 1.9 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain STN PF07660.14 AAZ35793.1 - 7.3e-07 28.9 0.0 2e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 Secretin and TonB N terminus short domain Peripla_BP_1 PF00532.21 AAZ35794.1 - 1e-49 169.5 0.0 1.2e-49 169.2 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_4 PF13407.6 AAZ35794.1 - 3.1e-20 72.9 1.8 3.8e-20 72.5 1.8 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain Transposase_mut PF00872.18 AAZ35795.1 - 3.1e-115 385.1 0.0 3.8e-115 384.8 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ35795.1 - 7.7e-05 23.0 0.0 0.00021 21.6 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain AAA_15 PF13175.6 AAZ35796.1 - 8.2e-51 173.8 0.0 1.2e-31 110.8 0.0 2.0 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 AAZ35796.1 - 4e-12 46.6 2.4 1.3e-07 31.7 0.7 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AAZ35796.1 - 1.7e-05 25.4 0.0 3.3e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 AAZ35796.1 - 0.0028 17.1 0.0 0.0043 16.5 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_27 PF13514.6 AAZ35796.1 - 0.0044 16.6 0.0 0.0092 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF2813 PF11398.8 AAZ35796.1 - 0.0062 15.9 0.7 0.08 12.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2813) Response_reg PF00072.24 AAZ35798.1 - 3.5e-29 101.2 0.0 4.9e-29 100.8 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain LytTR PF04397.15 AAZ35798.1 - 3.8e-22 78.3 0.0 5.7e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 LytTr DNA-binding domain B12-binding PF02310.19 AAZ35798.1 - 0.08 13.0 0.0 0.43 10.6 0.0 2.0 1 1 1 2 2 2 0 B12 binding domain TonB_dep_Rec PF00593.24 AAZ35799.1 - 2.8e-45 156.1 38.7 2.8e-45 156.1 38.7 1.9 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 AAZ35799.1 - 4.4e-18 65.8 1.5 1.1e-17 64.5 1.5 1.8 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 AAZ35799.1 - 2.8e-07 29.9 10.2 8.4e-07 28.3 5.4 3.1 2 1 0 2 2 2 1 Outer membrane protein beta-barrel family UDG PF03167.19 AAZ35800.1 - 1.5e-23 83.5 0.1 2.1e-23 83.0 0.1 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily AIRS_C PF02769.22 AAZ35802.1 - 4.2e-38 130.9 0.7 6.4e-38 130.3 0.7 1.3 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 AAZ35802.1 - 8e-16 58.5 0.9 1.7e-15 57.5 0.9 1.6 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain Carb_kinase PF01256.17 AAZ35803.1 - 1.8e-58 197.9 5.1 1.8e-58 197.9 5.1 1.6 2 0 0 2 2 2 1 Carbohydrate kinase YjeF_N PF03853.15 AAZ35803.1 - 4.2e-37 127.7 6.6 8.7e-37 126.6 2.9 2.4 2 0 0 2 2 2 1 YjeF-related protein N-terminus HK PF02110.15 AAZ35803.1 - 9.6e-06 25.2 0.6 2.2e-05 24.0 0.2 1.7 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.12 AAZ35803.1 - 0.00033 20.1 0.0 0.00069 19.1 0.0 1.5 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase BPD_transp_1 PF00528.22 AAZ35804.1 - 1.7e-17 63.7 18.1 1.7e-17 63.7 18.1 1.7 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Amidase PF01425.21 AAZ35805.1 - 3.5e-72 243.8 0.0 1.4e-71 241.9 0.0 1.7 1 1 0 1 1 1 1 Amidase NUDIX PF00293.28 AAZ35806.1 - 1.1e-21 77.3 0.0 1.2e-21 77.1 0.0 1.0 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 AAZ35806.1 - 3.7e-06 26.9 0.0 4.6e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain OAM_dimer PF16554.5 AAZ35806.1 - 0.087 13.3 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Dimerisation domain of d-ornithine 4,5-aminomutase TetR_C_6 PF13977.6 AAZ35807.1 - 4.6e-32 110.6 3.9 1.5e-31 109.0 0.8 2.0 2 0 0 2 2 2 1 BetI-type transcriptional repressor, C-terminal TetR_N PF00440.23 AAZ35807.1 - 2.1e-08 33.8 0.1 4.2e-08 32.9 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family ADP_PFK_GK PF04587.15 AAZ35807.1 - 0.12 11.0 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region LacI PF00356.21 AAZ35807.1 - 0.15 11.9 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family Staygreen PF12638.7 AAZ35807.1 - 0.15 11.9 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Staygreen protein TetR_C_28 PF17937.1 AAZ35807.1 - 0.18 12.3 7.8 0.28 11.7 2.0 3.3 1 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain MFS_1 PF07690.16 AAZ35808.1 - 4.9e-44 150.7 67.9 8.6e-42 143.3 34.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 AAZ35808.1 - 0.0005 19.5 10.3 0.0005 19.5 10.3 2.7 1 1 1 2 2 2 2 Uncharacterised MFS-type transporter YbfB Phage_GPD PF05954.11 AAZ35809.1 - 2.9e-49 168.0 2.6 1.1e-48 166.1 0.4 2.0 2 0 0 2 2 2 2 Phage late control gene D protein (GPD) DnaJ PF00226.31 AAZ35810.1 - 0.00013 22.0 0.0 0.00034 20.7 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain DUF4096 PF13340.6 AAZ35811.1 - 5.8e-25 87.3 0.4 1.5e-24 86.0 0.4 1.8 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1 PF01609.21 AAZ35811.1 - 3.2e-14 53.1 0.0 5.7e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AAZ35811.1 - 7.2e-10 39.1 0.2 2.1e-09 37.6 0.2 1.9 1 0 0 1 1 1 1 Transposase DDE domain HTH_Tnp_Tc3_2 PF01498.18 AAZ35811.1 - 0.061 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Transposase Aldo_ket_red PF00248.21 AAZ35812.1 - 5.7e-65 219.4 0.0 6.5e-65 219.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FAA_hydrolase PF01557.18 AAZ35813.1 - 1.1e-56 192.0 0.0 1.5e-56 191.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 AAZ35813.1 - 7.3e-25 87.2 0.0 1.3e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal SMC_N PF02463.19 AAZ35814.1 - 1.8e-34 119.1 0.0 2.1e-34 118.9 0.0 1.0 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AAZ35814.1 - 9.4e-08 32.8 0.0 2.1e-07 31.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 AAZ35814.1 - 8.9e-07 29.0 0.0 1.4e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AAZ35814.1 - 8.1e-05 22.5 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_13 PF13166.6 AAZ35814.1 - 0.00055 18.7 0.0 0.00088 18.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAZ35814.1 - 0.0014 18.4 0.1 0.0092 15.7 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AAZ35814.1 - 0.0061 16.9 2.4 0.063 13.7 2.4 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_27 PF13514.6 AAZ35814.1 - 0.013 15.2 0.0 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AAZ35814.1 - 0.027 15.0 0.1 0.37 11.3 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_18 PF13238.6 AAZ35814.1 - 0.036 14.6 0.1 1.2 9.7 0.0 2.8 1 1 2 3 3 3 0 AAA domain Ribosomal_L12 PF00542.19 AAZ35815.1 - 0.018 15.4 0.0 0.04 14.3 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L7/L12 C-terminal domain Glyco_hydro_30 PF02055.16 AAZ35815.1 - 0.037 13.0 0.0 0.05 12.6 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 30 TIM-barrel domain DisA-linker PF10635.9 AAZ35815.1 - 0.19 11.5 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 DisA bacterial checkpoint controller linker region DUF3509 PF12021.8 AAZ35816.1 - 0.047 13.4 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3509) BPD_transp_1 PF00528.22 AAZ35817.1 - 2.1e-21 76.5 17.2 2.1e-21 76.5 17.2 1.5 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Stevor PF17410.2 AAZ35817.1 - 0.51 9.8 1.8 0.81 9.2 1.8 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame MTS PF05175.14 AAZ35818.1 - 2e-20 73.0 0.0 1.1e-16 60.8 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_31 PF13847.6 AAZ35818.1 - 1e-12 48.1 0.0 1.5e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAZ35818.1 - 2.1e-09 38.0 0.0 2.4e-08 34.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 AAZ35818.1 - 1e-06 28.8 0.0 2.9e-06 27.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 AAZ35818.1 - 2e-06 27.5 0.0 3.8e-06 26.5 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 AAZ35818.1 - 5.8e-06 26.1 0.0 9.6e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Cons_hypoth95 PF03602.15 AAZ35818.1 - 3.2e-05 23.6 0.0 6e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_15 PF09445.10 AAZ35818.1 - 4.3e-05 23.2 0.0 6.9e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_23 PF13489.6 AAZ35818.1 - 0.00012 22.0 0.0 0.00037 20.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 AAZ35818.1 - 0.00028 20.6 0.0 0.00076 19.2 0.0 1.7 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.12 AAZ35818.1 - 0.00059 20.5 0.0 0.0021 18.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAZ35818.1 - 0.0006 20.4 0.0 0.0025 18.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 AAZ35818.1 - 0.00078 18.8 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 AAZ35818.1 - 0.00078 18.8 0.0 0.0015 17.8 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Met_10 PF02475.16 AAZ35818.1 - 0.0063 16.3 0.0 0.0094 15.7 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.19 AAZ35818.1 - 0.0074 16.1 0.0 0.029 14.1 0.0 1.8 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TrmK PF04816.12 AAZ35818.1 - 0.02 14.4 0.0 0.061 12.8 0.0 1.7 2 0 0 2 2 2 0 tRNA (adenine(22)-N(1))-methyltransferase PrmC_N PF17827.1 AAZ35818.1 - 0.034 14.7 0.0 0.083 13.5 0.0 1.7 1 0 0 1 1 1 0 PrmC N-terminal domain Methyltransf_20 PF12147.8 AAZ35818.1 - 0.13 11.3 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase GD_AH_C PF04295.13 AAZ35818.1 - 0.18 10.6 0.0 0.24 10.2 0.0 1.1 1 0 0 1 1 1 0 D-galactarate dehydratase / Altronate hydrolase, C terminus N6_Mtase PF02384.16 AAZ35818.1 - 0.24 10.6 0.0 0.5 9.6 0.0 1.5 1 1 0 1 1 1 0 N-6 DNA Methylase His_Phos_1 PF00300.22 AAZ35820.1 - 1.9e-42 145.2 0.0 2.2e-42 144.9 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) MCPsignal PF00015.21 AAZ35821.1 - 1.8e-36 125.5 21.5 2.1e-36 125.3 20.3 1.7 1 1 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain PAS_3 PF08447.12 AAZ35821.1 - 7.3e-28 96.7 0.0 9.2e-13 48.3 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 AAZ35821.1 - 1.3e-24 86.4 0.0 1.4e-12 47.8 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 AAZ35821.1 - 9.8e-20 70.9 0.1 6.1e-09 36.1 0.0 2.8 3 0 0 3 3 3 2 PAS fold PAS PF00989.25 AAZ35821.1 - 2.1e-14 53.4 0.0 6.7e-08 32.5 0.0 2.8 2 1 0 2 2 2 2 PAS fold PAS_8 PF13188.7 AAZ35821.1 - 1.3e-07 31.4 0.1 0.0035 17.3 0.0 2.8 2 0 0 2 2 2 2 PAS domain G-patch_2 PF12656.7 AAZ35821.1 - 0.0079 16.3 0.0 0.61 10.2 0.0 2.5 2 0 0 2 2 2 1 G-patch domain PAS_11 PF14598.6 AAZ35821.1 - 0.051 13.7 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 PAS domain DUF2242 PF10001.9 AAZ35821.1 - 0.099 12.8 1.3 0.23 11.7 1.3 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2242) Spc24 PF08286.11 AAZ35821.1 - 3.2 8.1 5.9 0.58 10.4 0.2 2.5 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 T7SS_ESX_EspC PF10824.8 AAZ35821.1 - 6.5 7.3 15.8 1.5 9.4 0.5 3.7 2 1 2 4 4 4 0 Excreted virulence factor EspC, type VII ESX diderm TMF_TATA_bd PF12325.8 AAZ35821.1 - 8.5 6.6 7.5 1.6 9.0 0.2 2.8 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding OpuAC PF04069.12 AAZ35822.1 - 2.8e-55 187.7 0.7 3.2e-55 187.5 0.7 1.0 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system DNA_pol_A PF00476.20 AAZ35823.1 - 4.6e-151 503.1 0.0 6.7e-151 502.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A 5_3_exonuc_N PF02739.16 AAZ35823.1 - 7.3e-50 169.0 0.0 1.2e-49 168.3 0.0 1.3 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 AAZ35823.1 - 1e-27 96.5 0.0 2.7e-27 95.2 0.0 1.8 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold DNA_pol_A_exo1 PF01612.20 AAZ35823.1 - 6.8e-27 94.3 1.8 2.6e-26 92.4 0.3 2.6 3 0 0 3 3 3 1 3'-5' exonuclease DnaA_N PF11638.8 AAZ35823.1 - 0.047 13.4 0.1 3.8 7.3 0.0 2.7 2 0 0 2 2 2 0 DnaA N-terminal domain EamA PF00892.20 AAZ35824.1 - 1.2e-18 67.6 39.9 8.6e-10 38.9 15.7 2.0 2 0 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 AAZ35824.1 - 0.00069 18.9 5.2 0.0011 18.2 5.2 1.4 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport TMEM234 PF10639.9 AAZ35824.1 - 0.001 19.1 10.3 0.12 12.4 0.7 2.8 3 0 0 3 3 3 2 Putative transmembrane family 234 UAA PF08449.11 AAZ35824.1 - 0.0037 16.5 6.0 0.11 11.6 4.0 2.5 1 1 1 2 2 2 2 UAA transporter family Nuc_sug_transp PF04142.15 AAZ35824.1 - 0.0088 15.3 0.1 0.8 8.8 0.0 2.3 2 0 0 2 2 2 2 Nucleotide-sugar transporter Ceramidase PF05875.12 AAZ35824.1 - 0.042 13.3 1.6 0.075 12.4 1.6 1.4 1 0 0 1 1 1 0 Ceramidase Mtc PF03820.17 AAZ35824.1 - 0.17 10.9 1.9 0.21 10.6 0.8 1.7 1 1 0 1 1 1 0 Tricarboxylate carrier Amidohydro_2 PF04909.14 AAZ35825.1 - 4.6e-16 59.4 0.1 5.4e-16 59.2 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase Rsa3 PF14615.6 AAZ35825.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Ribosome-assembly protein 3 DIOX_N PF14226.6 AAZ35826.1 - 1.7e-32 112.6 0.0 2.6e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 AAZ35826.1 - 9.8e-24 83.8 0.0 1.7e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily adh_short PF00106.25 AAZ35828.1 - 3.6e-51 173.4 0.0 4.9e-51 173.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAZ35828.1 - 3.4e-46 157.7 0.0 4.3e-46 157.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAZ35828.1 - 9.1e-09 35.5 0.3 1.7e-08 34.6 0.3 1.4 1 1 0 1 1 1 1 KR domain CRCB PF02537.15 AAZ35829.1 - 2.3e-23 82.3 8.5 2.7e-23 82.1 8.5 1.0 1 0 0 1 1 1 1 CrcB-like protein, Camphor Resistance (CrcB) TagF_N PF09867.9 AAZ35830.1 - 2.4e-22 79.4 0.3 5.4e-22 78.3 0.1 1.6 2 0 0 2 2 2 1 TagF N-terminal domain, Type VI secretion system-associated Aminotran_3 PF00202.21 AAZ35831.1 - 6.9e-89 298.3 0.0 8.6e-89 298.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 AAZ35831.1 - 0.011 14.9 0.0 0.36 10.0 0.0 2.1 2 0 0 2 2 2 0 Aminotransferase class I and II DUF1375 PF07119.12 AAZ35832.1 - 4.6e-06 26.9 4.1 6.9e-05 23.2 4.1 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1375) NTP_transf_3 PF12804.7 AAZ35834.1 - 1.7e-22 80.5 1.9 2.8e-22 79.8 1.9 1.5 1 1 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 AAZ35834.1 - 2.1e-17 62.1 20.2 3e-07 29.9 4.9 5.9 3 1 3 6 6 6 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 AAZ35834.1 - 2.9e-11 43.4 0.0 4.6e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase IspD PF01128.19 AAZ35834.1 - 7e-08 32.5 2.8 1.2e-07 31.7 1.5 1.9 1 1 0 2 2 2 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Hexapep_2 PF14602.6 AAZ35834.1 - 1.7e-07 30.9 19.5 7.8e-05 22.4 2.2 5.1 5 1 0 5 5 5 2 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.19 AAZ35834.1 - 0.00014 21.9 0.0 0.00019 21.4 0.0 1.3 1 1 0 1 1 1 1 Cytidylyltransferase CofC PF01983.16 AAZ35834.1 - 0.002 17.4 0.0 0.004 16.4 0.0 1.4 1 0 0 1 1 1 1 Guanylyl transferase CofC like Fucokinase PF07959.12 AAZ35834.1 - 0.051 12.5 0.1 0.21 10.5 0.1 1.8 1 1 1 2 2 2 0 L-fucokinase SBP_bac_3 PF00497.20 AAZ35835.1 - 1.2e-10 41.2 0.0 6.2e-10 38.9 0.0 1.8 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 LysR_substrate PF03466.20 AAZ35835.1 - 0.00012 21.5 0.0 0.00024 20.5 0.0 1.4 1 1 0 1 1 1 1 LysR substrate binding domain Phosphonate-bd PF12974.7 AAZ35835.1 - 0.0019 17.9 0.0 0.0036 16.9 0.0 1.6 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein FtsQ PF03799.15 AAZ35836.1 - 2.7e-21 76.6 0.1 4.8e-21 75.8 0.1 1.4 1 0 0 1 1 1 1 Cell division protein FtsQ POTRA_1 PF08478.10 AAZ35836.1 - 9.8e-19 67.4 0.2 2.3e-18 66.3 0.2 1.6 1 0 0 1 1 1 1 POTRA domain, FtsQ-type META PF03724.16 AAZ35837.1 - 1.5e-26 92.5 0.0 1.9e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 META domain OprD PF03573.13 AAZ35838.1 - 8.8e-150 499.1 7.1 1e-149 498.9 7.1 1.0 1 0 0 1 1 1 1 outer membrane porin, OprD family DDE_Tnp_1 PF01609.21 AAZ35839.1 - 6.3e-36 124.0 1.1 9.7e-36 123.4 0.8 1.4 2 0 0 2 2 2 1 Transposase DDE domain DUF772 PF05598.11 AAZ35839.1 - 2.8e-19 68.9 0.1 5.6e-19 67.9 0.1 1.5 1 0 0 1 1 1 1 Transposase domain (DUF772) DDE_Tnp_1_6 PF13751.6 AAZ35839.1 - 4.7e-07 30.1 0.6 8.4e-07 29.3 0.6 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 AAZ35839.1 - 1.3e-05 25.2 0.1 2.1e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 AAZ35839.1 - 0.00042 20.0 0.7 0.00069 19.3 0.7 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1_2 PF13586.6 AAZ35839.1 - 0.012 16.0 0.8 0.024 15.0 0.8 1.5 1 0 0 1 1 1 0 Transposase DDE domain HTH_36 PF13730.6 AAZ35840.1 - 5.4e-09 35.9 0.0 1e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain DnaT PF17948.1 AAZ35840.1 - 1.2e-07 31.3 0.0 2.2e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 DnaT DNA-binding domain HTH_24 PF13412.6 AAZ35840.1 - 0.00029 20.3 0.0 0.00055 19.5 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 AAZ35840.1 - 0.00033 20.5 0.0 0.0007 19.4 0.0 1.5 1 1 0 1 1 1 1 MarR family HTH_12 PF08461.10 AAZ35840.1 - 0.0022 17.9 0.0 0.0048 16.8 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain HTH_11 PF08279.12 AAZ35840.1 - 0.0045 16.9 0.1 0.0093 15.9 0.1 1.5 1 0 0 1 1 1 1 HTH domain RP-C PF03428.13 AAZ35840.1 - 0.028 14.1 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 Replication protein C N-terminal domain HTH_IclR PF09339.10 AAZ35840.1 - 0.035 13.9 0.0 0.085 12.7 0.0 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_Crp_2 PF13545.6 AAZ35840.1 - 0.048 13.6 0.0 0.097 12.7 0.0 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain GntR PF00392.21 AAZ35840.1 - 0.074 12.7 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family MarR PF01047.22 AAZ35840.1 - 0.077 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 MarR family FaeA PF04703.12 AAZ35840.1 - 0.092 13.1 0.0 0.28 11.6 0.0 1.8 1 0 0 1 1 1 0 FaeA-like protein HTH_20 PF12840.7 AAZ35840.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_AsnC-type PF13404.6 AAZ35840.1 - 0.13 12.1 0.1 0.25 11.2 0.1 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain MerR PF00376.23 AAZ35840.1 - 0.18 11.6 0.1 0.43 10.4 0.1 1.6 1 0 0 1 1 1 0 MerR family regulatory protein Acetyltransf_1 PF00583.25 AAZ35841.1 - 4.5e-14 52.7 0.0 5.7e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AAZ35841.1 - 3.8e-08 33.3 0.0 4.8e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAZ35841.1 - 2.3e-07 31.1 0.0 3.4e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AAZ35841.1 - 0.0039 17.2 0.0 0.0054 16.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAZ35841.1 - 0.022 14.7 0.0 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_3 PF13302.7 AAZ35841.1 - 0.025 15.2 0.0 0.035 14.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 AAZ35841.1 - 0.038 13.7 0.0 0.13 11.9 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PCP_red PF08369.10 AAZ35841.1 - 0.17 12.1 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit Sulfatase PF00884.23 AAZ35842.1 - 3e-46 158.2 0.2 4.3e-46 157.7 0.2 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 AAZ35842.1 - 0.00016 21.4 0.1 0.00052 19.7 0.0 1.7 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 AAZ35842.1 - 0.044 12.4 0.0 0.061 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) FA_desaturase PF00487.24 AAZ35842.1 - 0.052 13.4 3.6 0.092 12.6 3.6 1.3 1 0 0 1 1 1 0 Fatty acid desaturase DUF2838 PF10998.8 AAZ35842.1 - 0.087 13.1 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2838) Metalloenzyme PF01676.18 AAZ35842.1 - 0.099 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily ANTAR PF03861.14 AAZ35843.1 - 4.2e-12 45.7 2.9 1.1e-11 44.3 2.9 1.7 1 0 0 1 1 1 1 ANTAR domain ABC_tran PF00005.27 AAZ35844.1 - 5.1e-24 85.3 0.0 7.8e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAZ35844.1 - 1.6e-05 24.9 0.0 0.0022 17.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAZ35844.1 - 4.2e-05 23.1 0.0 0.022 14.2 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 AAZ35844.1 - 0.00052 20.2 0.3 0.052 13.8 0.3 2.4 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 AAZ35844.1 - 0.0024 17.8 0.1 0.0043 17.0 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase DUF3142 PF11340.8 AAZ35844.1 - 0.018 14.8 0.0 0.027 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3142) AAA_22 PF13401.6 AAZ35844.1 - 0.021 15.1 0.0 0.058 13.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AAZ35844.1 - 0.026 14.3 0.3 0.072 12.8 0.3 1.8 1 1 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 AAZ35844.1 - 0.072 13.5 0.3 0.19 12.1 0.3 1.8 1 1 0 1 1 1 0 AAA ATPase domain DUF815 PF05673.13 AAZ35844.1 - 0.13 11.4 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Guanylate_kin PF00625.21 AAZ35844.1 - 0.22 11.2 0.0 0.36 10.5 0.0 1.2 1 0 0 1 1 1 0 Guanylate kinase Pribosyltran PF00156.27 AAZ35845.1 - 4.1e-12 45.9 0.0 5.1e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 AAZ35845.1 - 0.0011 18.5 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 AAZ35845.1 - 0.094 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase CHDNT PF08073.12 AAZ35845.1 - 0.19 11.7 0.1 0.43 10.6 0.0 1.6 2 0 0 2 2 2 0 CHDNT (NUC034) domain zf-ANAPC11 PF12861.7 AAZ35846.1 - 0.018 15.1 0.1 4.2 7.5 0.1 2.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 AAZ35846.1 - 0.022 14.6 2.7 4.8 7.1 0.1 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain HscB_4_cys PF18256.1 AAZ35846.1 - 0.21 11.4 4.3 0.56 10.1 0.2 2.6 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif PhnA_Zn_Ribbon PF08274.12 AAZ35846.1 - 0.29 11.1 3.5 1.4 9.0 0.3 2.2 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf_UBZ PF18439.1 AAZ35846.1 - 0.4 10.3 3.3 6.8 6.4 0.5 2.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger UPF0547 PF10571.9 AAZ35846.1 - 0.55 10.4 11.0 0.73 10.0 0.2 2.9 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 zinc-ribbons_6 PF07191.12 AAZ35846.1 - 0.97 9.5 3.5 20 5.2 3.5 2.4 1 1 0 1 1 1 0 zinc-ribbons Beta_helix PF13229.6 AAZ35847.1 - 1.2e-16 60.9 29.7 7.5e-13 48.6 17.5 2.2 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 AAZ35847.1 - 8.6e-14 51.4 12.0 8.6e-07 28.5 8.2 2.2 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) ACP_syn_III PF08545.10 AAZ35848.1 - 0.073 12.9 0.0 0.16 11.8 0.0 1.6 1 1 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Sigma70_r4 PF04545.16 AAZ35849.1 - 1.3e-18 66.2 0.4 4.4e-18 64.5 0.2 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 AAZ35849.1 - 1.7e-18 66.2 0.1 3.3e-17 62.0 0.0 2.3 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r3 PF04539.16 AAZ35849.1 - 7.2e-13 48.4 0.2 2.7e-11 43.4 0.0 2.6 2 1 0 2 2 2 1 Sigma-70 region 3 Sigma70_r4_2 PF08281.12 AAZ35849.1 - 4.6e-09 35.8 1.1 6.7e-09 35.3 0.3 1.7 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_23 PF13384.6 AAZ35849.1 - 5.1e-05 22.9 0.3 0.00032 20.4 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain UPF0122 PF04297.14 AAZ35849.1 - 0.0025 18.0 0.0 0.0069 16.6 0.0 1.7 1 0 0 1 1 1 1 Putative helix-turn-helix protein, YlxM / p13 like HTH_30 PF13556.6 AAZ35849.1 - 0.0051 16.6 0.0 0.072 12.9 0.0 2.4 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain MarR_2 PF12802.7 AAZ35849.1 - 0.021 14.7 1.6 0.17 11.8 0.1 2.8 3 0 0 3 3 3 0 MarR family HTH_AsnC-type PF13404.6 AAZ35849.1 - 0.027 14.3 0.0 0.094 12.6 0.0 2.0 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_38 PF13936.6 AAZ35849.1 - 0.031 14.0 0.0 0.082 12.7 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain GerE PF00196.19 AAZ35849.1 - 0.05 13.2 0.0 0.11 12.1 0.0 1.6 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family Ank_4 PF13637.6 AAZ35850.1 - 3.6e-25 88.0 3.7 1.1e-07 32.2 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 AAZ35850.1 - 4.2e-21 75.3 0.4 7.5e-13 48.9 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 AAZ35850.1 - 3.5e-18 63.8 0.3 1e-06 28.6 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 AAZ35850.1 - 8.6e-16 57.8 3.7 2.2e-07 31.0 0.2 3.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 AAZ35850.1 - 3e-15 55.9 5.1 4.1e-07 30.2 0.0 4.1 4 1 1 5 5 5 3 Ankyrin repeat MFS_1 PF07690.16 AAZ35851.1 - 1.1e-22 80.5 62.6 5.9e-14 51.8 35.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 AAZ35851.1 - 6e-05 21.6 10.3 6e-05 21.6 10.3 2.1 2 0 0 2 2 2 1 Transmembrane secretion effector MFS_2 PF13347.6 AAZ35851.1 - 9.8e-05 21.1 24.2 0.011 14.3 8.6 2.8 2 1 0 2 2 2 2 MFS/sugar transport protein LacY_symp PF01306.19 AAZ35851.1 - 0.00019 20.4 2.3 0.00019 20.4 2.3 2.4 2 1 0 3 3 3 1 LacY proton/sugar symporter MFS_1_like PF12832.7 AAZ35851.1 - 0.021 13.7 15.6 0.011 14.7 7.3 2.4 2 1 0 2 2 2 0 MFS_1 like family TraD PF06412.11 AAZ35851.1 - 0.073 12.9 2.9 0.55 10.1 0.3 2.5 2 0 0 2 2 2 0 Conjugal transfer protein TraD MFS_4 PF06779.14 AAZ35851.1 - 0.11 11.8 34.4 0.38 10.0 13.6 2.1 2 0 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB DUF4225 PF13988.6 AAZ35851.1 - 0.2 11.2 0.5 0.48 10.0 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4225) Ribosomal_L22 PF00237.19 AAZ35852.1 - 2e-34 117.9 1.3 2.2e-34 117.8 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e LysR_substrate PF03466.20 AAZ35853.1 - 1.5e-43 148.6 2.8 2.7e-43 147.8 2.8 1.4 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ35853.1 - 1.3e-21 76.2 0.5 3.4e-21 74.9 0.5 1.8 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_8 PF02954.19 AAZ35853.1 - 0.001 18.8 1.3 0.0014 18.4 0.4 1.7 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family HTH_24 PF13412.6 AAZ35853.1 - 0.0017 17.9 0.2 0.0035 16.9 0.2 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 AAZ35853.1 - 0.0019 18.0 2.1 0.0043 16.8 2.1 1.6 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain MarR_2 PF12802.7 AAZ35853.1 - 0.0031 17.4 0.2 0.0093 15.8 0.2 1.9 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 AAZ35853.1 - 0.0064 16.5 0.2 0.018 15.1 0.2 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_30 PF13556.6 AAZ35853.1 - 0.01 15.6 0.1 0.022 14.6 0.1 1.5 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Sigma70_r4 PF04545.16 AAZ35853.1 - 0.035 13.6 0.1 0.092 12.3 0.1 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.6 AAZ35853.1 - 0.068 12.6 0.1 0.17 11.3 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.6 AAZ35853.1 - 0.087 13.0 0.1 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Iron_traffic PF04362.14 AAZ35854.1 - 8.7e-40 134.3 0.1 9.6e-40 134.2 0.1 1.0 1 0 0 1 1 1 1 Bacterial Fe(2+) trafficking tRNA-synt_2b PF00587.25 AAZ35855.1 - 3.2e-49 167.3 0.0 4.8e-49 166.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_edit PF04073.15 AAZ35855.1 - 1.2e-23 83.5 0.0 2.3e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain HGTP_anticodon PF03129.20 AAZ35855.1 - 7.8e-15 54.8 0.0 1.5e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain Transcrip_reg PF01709.20 AAZ35856.1 - 2.5e-93 311.9 0.0 2.8e-93 311.8 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator SBP_bac_3 PF00497.20 AAZ35857.1 - 1.3e-59 201.3 0.0 1.5e-59 201.2 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 AAZ35857.1 - 8.8e-07 29.1 0.0 1.5e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site NMT1 PF09084.11 AAZ35857.1 - 0.0054 16.7 0.0 0.014 15.4 0.0 1.7 1 1 1 2 2 2 1 NMT1/THI5 like DUF1289 PF06945.13 AAZ35858.1 - 5e-17 61.4 5.2 6e-17 61.2 5.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1289) His_kinase PF06580.13 AAZ35859.1 - 3.9e-23 81.6 0.0 7.5e-23 80.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase DUF2070 PF09843.9 AAZ35859.1 - 0.078 11.3 4.0 0.1 10.9 4.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) HTH_6 PF01418.17 AAZ35860.1 - 8e-23 80.2 0.0 1.7e-22 79.2 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain, rpiR family SIS PF01380.22 AAZ35860.1 - 1.1e-15 57.6 0.4 1.9e-15 56.9 0.4 1.4 1 0 0 1 1 1 1 SIS domain SIS_2 PF13580.6 AAZ35860.1 - 0.00072 19.6 1.1 0.017 15.2 0.0 2.3 1 1 1 2 2 2 1 SIS domain Amidase PF01425.21 AAZ35861.1 - 1.9e-83 281.0 1.4 6.3e-83 279.2 1.4 1.8 1 1 0 1 1 1 1 Amidase Mu-transpos_C PF09299.11 AAZ35861.1 - 0.027 14.4 0.0 0.077 13.0 0.0 1.7 2 0 0 2 2 2 0 Mu transposase, C-terminal DUF903 PF06004.12 AAZ35862.1 - 0.044 13.7 0.7 62 3.6 0.0 4.9 6 0 0 6 6 6 0 Bacterial protein of unknown function (DUF903) Phage_holin_3_6 PF07332.11 AAZ35862.1 - 0.49 10.4 6.6 1.2 9.2 6.6 1.6 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III AAA_33 PF13671.6 AAZ35863.1 - 2.6e-36 124.9 0.1 5.1e-36 124.0 0.1 1.5 1 0 0 1 1 1 1 AAA domain APH PF01636.23 AAZ35863.1 - 1.2e-06 28.7 0.1 1.2e-06 28.7 0.1 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family KTI12 PF08433.10 AAZ35863.1 - 0.0026 17.3 0.0 0.0041 16.6 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 DUF3337 PF11816.8 AAZ35863.1 - 0.091 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) DUF3952 PF13130.6 AAZ35864.1 - 0.12 12.5 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3952) DUF2474 PF10617.9 AAZ35865.1 - 7.1e-20 70.6 8.8 8.1e-20 70.4 8.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2474) LysM PF01476.20 AAZ35866.1 - 2.3e-13 50.0 0.1 8.6e-13 48.1 0.0 2.0 2 0 0 2 2 2 1 LysM domain FlgT_C PF16538.5 AAZ35866.1 - 0.099 13.2 0.0 0.3 11.6 0.0 1.9 1 0 0 1 1 1 0 Flagellar assembly protein T, C-terminal domain MethyltransfD12 PF02086.15 AAZ35867.1 - 8.7e-22 78.0 0.0 1.2e-21 77.6 0.0 1.2 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase Baculo_RING PF05883.11 AAZ35867.1 - 0.00013 22.0 0.0 0.00022 21.2 0.0 1.3 1 0 0 1 1 1 1 Baculovirus U-box/Ring-like domain FHIPEP PF00771.20 AAZ35868.1 - 3.1e-259 861.9 12.4 3.7e-259 861.7 12.4 1.0 1 0 0 1 1 1 1 FHIPEP family DUF2678 PF10856.8 AAZ35868.1 - 0.028 14.4 1.9 0.074 13.0 1.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2678) DUF2946 PF11162.8 AAZ35869.1 - 5.8e-16 59.2 16.4 7.5e-16 58.8 16.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2946) zf_C2H2_6 PF18450.1 AAZ35869.1 - 0.038 13.7 1.0 0.073 12.8 1.0 1.4 1 0 0 1 1 1 0 Zinc Finger domain Flp_Fap PF04964.14 AAZ35870.1 - 1.3e-14 53.7 2.4 1.5e-14 53.5 2.4 1.1 1 0 0 1 1 1 1 Flp/Fap pilin component MFS_1 PF07690.16 AAZ35871.1 - 2.8e-31 108.8 86.9 4.5e-30 104.8 48.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC_membrane_2 PF06472.15 AAZ35872.1 - 2.3e-61 207.6 6.2 3.5e-61 207.0 6.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 SbmA_BacA PF05992.12 AAZ35872.1 - 3e-35 122.2 7.2 4.2e-35 121.7 7.2 1.1 1 0 0 1 1 1 1 SbmA/BacA-like family ABC_tran PF00005.27 AAZ35872.1 - 1.3e-15 58.1 0.0 4e-15 56.5 0.0 1.9 1 1 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 AAZ35872.1 - 2.6e-05 24.0 8.9 5.5e-05 23.0 8.9 1.6 1 1 0 1 1 1 1 ABC transporter transmembrane region Abhydrolase_9_N PF15420.6 AAZ35872.1 - 0.002 18.2 3.5 0.002 18.2 3.5 1.8 2 0 0 2 2 2 1 Alpha/beta-hydrolase family N-terminus AAA_29 PF13555.6 AAZ35872.1 - 0.0022 17.7 0.1 0.0055 16.4 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AAZ35872.1 - 0.013 15.9 0.0 0.05 14.0 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain DUF815 PF05673.13 AAZ35872.1 - 0.042 13.0 0.0 0.082 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.12 AAZ35872.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_21 PF13304.6 AAZ35872.1 - 0.13 12.0 0.5 0.29 10.9 0.1 1.7 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Phage_holin_3_6 PF07332.11 AAZ35872.1 - 2.9 8.0 9.4 0.66 10.0 0.2 2.3 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Yip1 PF04893.17 AAZ35872.1 - 2.9 7.6 16.9 2.5 7.8 2.8 2.6 3 0 0 3 3 3 0 Yip1 domain HD PF01966.22 AAZ35873.1 - 2.8e-11 43.7 0.7 6e-11 42.6 0.7 1.5 1 0 0 1 1 1 1 HD domain DUF4202 PF13875.6 AAZ35873.1 - 0.0015 18.4 0.3 0.0034 17.3 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4202) EAL PF00563.20 AAZ35874.1 - 1.3e-69 234.4 0.2 2.5e-69 233.4 0.2 1.5 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AAZ35874.1 - 6.4e-47 159.3 0.0 2e-46 157.7 0.0 1.9 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain PAS PF00989.25 AAZ35874.1 - 5.8e-13 48.8 0.1 5e-05 23.3 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 AAZ35874.1 - 2.1e-12 47.2 0.0 6.9e-09 35.9 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 AAZ35874.1 - 2.9e-09 37.1 0.0 2.3e-06 27.8 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 AAZ35874.1 - 1.1e-08 35.3 0.1 0.0011 19.2 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 AAZ35874.1 - 7e-07 29.1 0.0 4.8e-06 26.5 0.0 2.5 2 0 0 2 2 2 1 PAS domain FliJ PF02050.16 AAZ35875.1 - 5.2e-34 117.1 11.3 6.2e-34 116.9 11.3 1.1 1 0 0 1 1 1 1 Flagellar FliJ protein DUF745 PF05335.13 AAZ35875.1 - 0.0094 15.7 2.5 1 9.1 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF745) YscO-like PF16789.5 AAZ35875.1 - 0.045 13.8 4.0 0.11 12.5 0.6 2.0 2 0 0 2 2 2 0 YscO-like protein Tombus_P19 PF03220.13 AAZ35875.1 - 0.088 12.5 0.3 0.19 11.4 0.3 1.6 1 1 0 1 1 1 0 Tombusvirus P19 core protein DUF1598 PF07643.11 AAZ35875.1 - 0.57 10.5 2.3 8.7 6.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1598) HrpB7 PF09486.10 AAZ35875.1 - 0.71 10.2 10.7 0.56 10.6 0.6 2.4 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Acyltransferase PF01553.21 AAZ35876.1 - 4.2e-25 87.9 0.0 6e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase FliH PF02108.16 AAZ35877.1 - 2.8e-32 111.5 1.8 3.9e-32 111.0 1.8 1.2 1 0 0 1 1 1 1 Flagellar assembly protein FliH Trypan_PARP PF05887.11 AAZ35877.1 - 0.007 16.3 9.8 0.014 15.4 9.8 1.5 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) SPESP1 PF15754.5 AAZ35877.1 - 0.0095 15.2 1.2 0.014 14.6 1.2 1.3 1 0 0 1 1 1 1 Sperm equatorial segment protein 1 DUF5567 PF17722.1 AAZ35877.1 - 0.016 15.1 2.0 0.03 14.2 1.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5567) TonB_N PF16031.5 AAZ35877.1 - 4.1 7.9 13.6 8.4 6.9 13.6 1.4 1 0 0 1 1 1 0 TonB polyproline region NUDIX PF00293.28 AAZ35878.1 - 4e-15 56.0 0.0 5.5e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Peptidase_M1 PF01433.20 AAZ35878.1 - 0.084 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M1 domain Methyltr_RsmB-F PF01189.17 AAZ35879.1 - 2.2e-61 207.0 0.0 3.3e-61 206.5 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F NusB PF01029.18 AAZ35879.1 - 1.1e-22 80.7 0.0 1.7e-22 80.1 0.0 1.3 1 0 0 1 1 1 1 NusB family Methyltransf_25 PF13649.6 AAZ35879.1 - 4.9e-05 23.9 0.0 0.00014 22.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 AAZ35879.1 - 0.00013 22.2 0.0 0.00022 21.4 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 AAZ35879.1 - 0.00026 20.6 0.0 0.00047 19.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 AAZ35879.1 - 0.00037 20.3 0.0 0.00063 19.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmF_N PF17125.5 AAZ35879.1 - 0.00073 20.0 0.0 0.0013 19.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF PCMT PF01135.19 AAZ35879.1 - 0.002 17.9 0.0 0.0033 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 AAZ35879.1 - 0.027 15.5 0.3 0.35 11.9 0.0 2.7 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 AAZ35879.1 - 0.17 11.7 0.1 0.87 9.4 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain FhuF PF06276.12 AAZ35880.1 - 7.1e-24 85.1 0.1 1.4e-23 84.1 0.1 1.5 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter FhuF_C PF11575.8 AAZ35880.1 - 1.1e-06 28.4 3.1 2.1e-06 27.5 3.1 1.5 1 0 0 1 1 1 1 FhuF 2Fe-2S C-terminal domain LysR_substrate PF03466.20 AAZ35882.1 - 1.2e-39 135.8 3.9 1.6e-39 135.4 3.9 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ35882.1 - 4.4e-17 61.8 0.2 1.2e-16 60.4 0.2 1.8 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family DUF2437 PF10370.9 AAZ35883.1 - 0.00075 20.3 1.8 0.0015 19.4 0.6 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF2437) Transposase_mut PF00872.18 AAZ35884.1 - 5.5e-91 305.3 0.0 6.3e-91 305.1 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ35884.1 - 4.4e-05 23.8 0.0 0.00011 22.5 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain DUF4844 PF16133.5 AAZ35884.1 - 0.14 12.8 0.0 0.34 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) HATPase_c PF02518.26 AAZ35885.1 - 1.8e-22 80.0 0.0 3.3e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 AAZ35885.1 - 2.2e-11 44.0 4.8 1.1e-10 41.7 0.4 3.2 2 1 0 2 2 2 1 HAMP domain HisKA PF00512.25 AAZ35885.1 - 1.8e-06 27.9 2.1 1.8e-06 27.9 2.1 2.3 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 AAZ35885.1 - 0.0024 17.7 0.0 0.004 17.0 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Phage_sheath_1C PF17482.2 AAZ35885.1 - 0.025 14.5 0.2 0.079 13.0 0.2 1.7 1 1 0 1 1 1 0 Phage tail sheath C-terminal domain DUF4131 PF13567.6 AAZ35885.1 - 0.053 13.2 0.9 0.59 9.8 0.8 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) HATPase_c_2 PF13581.6 AAZ35885.1 - 0.057 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Exonuc_VII_L PF02601.15 AAZ35885.1 - 0.94 9.0 4.5 1.2 8.6 4.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit ETF PF01012.21 AAZ35886.1 - 5.1e-47 160.1 4.6 7.3e-47 159.6 4.6 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Ala_racemase_N PF01168.20 AAZ35886.1 - 0.00022 20.9 0.7 0.00022 20.9 0.7 1.4 2 0 0 2 2 2 1 Alanine racemase, N-terminal domain Transposase_mut PF00872.18 AAZ35888.1 - 1.5e-117 392.7 0.0 1.9e-117 392.3 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ35888.1 - 7.7e-05 23.0 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain DUF4844 PF16133.5 AAZ35888.1 - 0.23 12.0 0.0 0.55 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) MethyltransfD12 PF02086.15 AAZ35889.1 - 1.7e-20 73.8 0.0 2.2e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase Baculo_RING PF05883.11 AAZ35889.1 - 0.00018 21.5 0.0 0.0003 20.8 0.0 1.3 1 0 0 1 1 1 1 Baculovirus U-box/Ring-like domain CT_C_D PF02682.16 AAZ35890.1 - 6.3e-48 163.2 0.0 7.7e-48 162.9 0.0 1.1 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D ABC_tran PF00005.27 AAZ35891.1 - 3.2e-35 121.6 0.0 4.1e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAZ35891.1 - 1.1e-10 41.8 0.0 0.00048 20.0 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAZ35891.1 - 2.5e-08 33.7 0.3 4.9e-05 22.9 0.1 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AAZ35891.1 - 5.6e-07 29.9 0.1 2.3e-05 24.7 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAZ35891.1 - 0.00012 21.7 0.1 0.00028 20.5 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_ATPase PF09818.9 AAZ35891.1 - 0.00045 19.1 1.2 0.28 9.9 0.1 2.9 2 1 0 2 2 2 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 AAZ35891.1 - 0.00053 19.9 0.0 0.00094 19.1 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 AAZ35891.1 - 0.0019 18.6 0.3 0.0038 17.6 0.3 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 AAZ35891.1 - 0.0022 17.7 1.1 0.024 14.4 1.0 2.1 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 AAZ35891.1 - 0.0022 17.2 0.0 0.0036 16.5 0.0 1.3 1 1 0 1 1 1 1 NB-ARC domain MMR_HSR1 PF01926.23 AAZ35891.1 - 0.0034 17.4 0.0 0.0062 16.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase TniB PF05621.11 AAZ35891.1 - 0.0035 16.8 0.1 0.23 10.9 0.0 2.2 2 0 0 2 2 2 1 Bacterial TniB protein AAA_23 PF13476.6 AAZ35891.1 - 0.0058 17.2 0.0 0.0094 16.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 AAZ35891.1 - 0.0081 16.4 0.1 0.1 12.8 0.1 2.6 2 1 0 2 2 2 1 AAA domain APS_kinase PF01583.20 AAZ35891.1 - 0.017 15.0 0.0 1.6 8.6 0.0 2.5 2 1 0 2 2 2 0 Adenylylsulphate kinase FtsK_SpoIIIE PF01580.18 AAZ35891.1 - 0.023 14.1 1.5 0.029 13.7 0.0 1.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_24 PF13479.6 AAZ35891.1 - 0.024 14.3 0.0 0.046 13.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 AAZ35891.1 - 0.028 14.3 0.2 0.058 13.3 0.2 1.5 1 0 0 1 1 1 0 NACHT domain DUF87 PF01935.17 AAZ35891.1 - 0.031 14.4 0.1 0.039 14.0 0.1 1.4 1 1 0 1 1 1 0 Helicase HerA, central domain AAA_10 PF12846.7 AAZ35891.1 - 0.036 13.0 0.0 0.078 11.9 0.0 1.4 1 1 0 1 1 1 0 AAA-like domain AAA_15 PF13175.6 AAZ35891.1 - 0.04 13.6 0.0 0.06 13.0 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 AAZ35891.1 - 0.072 12.8 0.2 0.25 11.1 0.2 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.6 AAZ35891.1 - 0.078 13.1 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 AAZ35891.1 - 0.079 13.0 0.1 4.3 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ATPase PF06745.13 AAZ35891.1 - 0.079 12.3 0.1 0.66 9.3 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_18 PF13238.6 AAZ35891.1 - 0.079 13.5 0.0 0.28 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 AAZ35891.1 - 0.084 12.8 0.2 2.4 8.0 0.0 2.2 2 0 0 2 2 2 0 NTPase Resolvase PF00239.21 AAZ35891.1 - 0.085 13.0 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Resolvase, N terminal domain AAA_13 PF13166.6 AAZ35891.1 - 0.17 10.5 0.0 13 4.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 AAZ35891.1 - 0.22 11.4 0.1 0.32 10.9 0.1 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Bact_transglu_N PF08379.10 AAZ35892.1 - 6.9e-27 94.2 0.6 2.9e-26 92.2 0.4 2.1 2 0 0 2 2 2 1 Bacterial transglutaminase-like N-terminal region Transglut_core PF01841.19 AAZ35892.1 - 2.2e-21 76.4 0.0 3.8e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.12 AAZ35892.1 - 0.0003 20.3 0.0 0.00078 19.0 0.0 1.6 2 0 0 2 2 2 1 Transglutaminase-like domain Transglut_core3 PF13471.6 AAZ35892.1 - 0.13 12.1 0.5 1.4 8.8 0.1 2.2 2 0 0 2 2 2 0 Transglutaminase-like superfamily HTH_Tnp_1 PF01527.20 AAZ35893.1 - 5.6e-18 65.0 1.4 7.9e-18 64.6 1.4 1.2 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.6 AAZ35893.1 - 0.00015 21.7 0.2 0.00031 20.7 0.0 1.6 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 AAZ35893.1 - 0.0003 20.8 0.1 0.00058 19.9 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AAZ35893.1 - 0.00035 20.3 1.4 0.0011 18.7 0.1 2.2 2 1 0 2 2 2 1 Homeodomain-like domain KASH_CCD PF14662.6 AAZ35893.1 - 0.006 16.4 3.0 0.0068 16.3 3.0 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH TSC22 PF01166.18 AAZ35893.1 - 0.0078 16.5 2.3 0.01 16.1 1.0 1.7 2 0 0 2 2 2 1 TSC-22/dip/bun family FlxA PF14282.6 AAZ35893.1 - 0.019 14.9 1.6 0.029 14.4 1.6 1.3 1 0 0 1 1 1 0 FlxA-like protein DivIC PF04977.15 AAZ35893.1 - 0.036 13.8 4.3 0.062 13.1 4.3 1.4 1 1 0 1 1 1 0 Septum formation initiator Shugoshin_N PF07558.11 AAZ35893.1 - 0.041 13.8 0.6 0.072 13.0 0.6 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region BLOC1_2 PF10046.9 AAZ35893.1 - 0.045 14.1 0.4 0.066 13.5 0.4 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3287 PF11690.8 AAZ35893.1 - 0.046 13.4 2.1 0.24 11.1 0.6 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF3287) M PF02370.16 AAZ35893.1 - 0.057 14.0 0.8 0.23 12.1 0.3 2.2 1 1 1 2 2 2 0 M protein repeat DUF4140 PF13600.6 AAZ35893.1 - 0.097 13.1 3.3 0.21 12.0 3.3 1.7 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) ZapB PF06005.12 AAZ35893.1 - 0.42 11.1 7.6 3.5 8.1 4.2 2.2 1 1 2 3 3 3 0 Cell division protein ZapB ABC_tran_CTD PF16326.5 AAZ35893.1 - 0.54 10.5 7.5 0.12 12.6 4.3 1.7 2 0 0 2 2 2 0 ABC transporter C-terminal domain TP_methylase PF00590.20 AAZ35895.1 - 2.4e-44 151.8 0.2 2.8e-44 151.6 0.2 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Glyco_trans_1_4 PF13692.6 AAZ35896.1 - 3.2e-22 79.4 0.0 6.7e-22 78.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AAZ35896.1 - 0.00031 21.1 0.0 0.00061 20.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Phage_integrase PF00589.22 AAZ35897.1 - 5.7e-52 176.0 0.0 7.2e-52 175.6 0.0 1.1 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 AAZ35897.1 - 3.9e-20 71.9 2.8 2.5e-18 66.2 0.1 2.7 2 1 0 2 2 2 2 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 AAZ35897.1 - 1.8e-06 28.3 0.0 7e-06 26.4 0.0 2.0 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain DUF3435 PF11917.8 AAZ35897.1 - 0.045 12.7 0.1 0.1 11.5 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3435) Integrase_1 PF12835.7 AAZ35897.1 - 0.062 13.4 0.0 0.14 12.3 0.0 1.5 1 1 0 1 1 1 0 Integrase MMPL PF03176.15 AAZ35898.1 - 1.1e-30 106.7 25.3 1.3e-27 96.6 2.4 2.6 2 1 0 2 2 2 2 MMPL family ACR_tran PF00873.19 AAZ35898.1 - 2.2e-05 22.4 6.5 2.2e-05 22.4 6.5 2.2 2 0 0 2 2 2 1 AcrB/AcrD/AcrF family Patched PF02460.18 AAZ35898.1 - 0.0016 16.7 2.9 0.0016 16.7 2.9 2.7 3 0 0 3 3 3 1 Patched family SecD_SecF PF02355.16 AAZ35899.1 - 4.8e-66 221.7 9.5 4.8e-66 221.7 9.5 1.5 2 0 0 2 2 2 1 Protein export membrane protein Sec_GG PF07549.14 AAZ35899.1 - 2.9e-12 45.6 0.1 6.4e-12 44.5 0.1 1.6 1 0 0 1 1 1 1 SecD/SecF GG Motif Phage_holin_3_6 PF07332.11 AAZ35899.1 - 0.0073 16.3 2.2 0.0073 16.3 2.2 3.1 3 1 0 3 3 3 1 Putative Actinobacterial Holin-X, holin superfamily III Peptidase_M19 PF01244.21 AAZ35899.1 - 0.086 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) ADH_zinc_N PF00107.26 AAZ35900.1 - 1.4e-11 44.5 0.1 2.4e-11 43.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AAZ35900.1 - 1.2e-05 25.2 0.0 3e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 AAZ35900.1 - 0.031 13.6 0.2 0.048 13.0 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Epimerase PF01370.21 AAZ35900.1 - 0.033 13.6 0.1 0.044 13.2 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.25 AAZ35900.1 - 0.056 12.9 0.1 0.086 12.3 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase KR PF08659.10 AAZ35900.1 - 0.059 13.3 0.3 0.093 12.6 0.3 1.3 1 0 0 1 1 1 0 KR domain Ribosomal_S8 PF00410.19 AAZ35901.1 - 1.2e-48 164.2 0.0 1.4e-48 164.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S8 TDA11 PF17084.5 AAZ35901.1 - 0.18 10.7 0.1 0.22 10.4 0.1 1.1 1 0 0 1 1 1 0 Topoisomerase I damage affected protein 11 GerE PF00196.19 AAZ35902.1 - 2.1e-18 65.6 0.0 3.5e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Autoind_bind PF03472.15 AAZ35902.1 - 7.6e-05 22.2 0.1 0.00012 21.6 0.1 1.5 1 1 0 1 1 1 1 Autoinducer binding domain HTH_10 PF04967.12 AAZ35902.1 - 0.0022 17.8 0.2 0.066 13.0 0.1 2.7 2 1 0 2 2 2 1 HTH DNA binding domain Sigma70_r4 PF04545.16 AAZ35902.1 - 0.017 14.7 0.0 0.034 13.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_40 PF14493.6 AAZ35902.1 - 0.027 14.9 0.1 0.084 13.3 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain KRTDAP PF15200.6 AAZ35902.1 - 0.13 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Keratinocyte differentiation-associated BPD_transp_1 PF00528.22 AAZ35903.1 - 1.6e-36 125.8 11.9 1.6e-36 125.8 11.9 1.6 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component MoCF_biosynth PF00994.24 AAZ35904.1 - 2.5e-32 111.5 0.2 3e-32 111.3 0.2 1.0 1 0 0 1 1 1 1 Probable molybdopterin binding domain Aldedh PF00171.22 AAZ35905.1 - 3.9e-130 434.4 0.0 5e-130 434.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family YscW PF09619.10 AAZ35906.1 - 0.0012 19.2 0.0 0.0017 18.7 0.0 1.2 1 0 0 1 1 1 1 Type III secretion system lipoprotein chaperone (YscW) Acyl_transf_3 PF01757.22 AAZ35907.1 - 2.7e-23 82.6 36.8 5.1e-23 81.7 36.6 1.5 2 0 0 2 2 2 1 Acyltransferase family DUF3784 PF12650.7 AAZ35907.1 - 0.16 12.2 4.2 1.9 8.7 0.1 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF3784) Chorismate_bind PF00425.18 AAZ35908.1 - 8.5e-97 323.7 0.0 1.1e-96 323.4 0.0 1.1 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 AAZ35908.1 - 1.5e-21 77.1 0.0 6.3e-21 75.1 0.0 2.0 1 1 0 1 1 1 1 Anthranilate synthase component I, N terminal region Aldedh PF00171.22 AAZ35909.1 - 2e-22 79.4 6.0 8.6e-16 57.5 5.4 2.4 2 1 0 2 2 2 2 Aldehyde dehydrogenase family DUF2564 PF10819.8 AAZ35909.1 - 0.16 12.4 3.4 0.37 11.2 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2564) MCPsignal PF00015.21 AAZ35910.1 - 3e-40 137.8 37.5 1e-39 136.1 20.3 3.4 1 1 1 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain 4HB_MCP_1 PF12729.7 AAZ35910.1 - 1.3e-19 70.4 0.0 1.3e-19 70.4 0.0 3.7 3 1 0 3 3 3 1 Four helix bundle sensory module for signal transduction HAMP PF00672.25 AAZ35910.1 - 1.8e-14 53.8 14.7 2.2e-09 37.5 0.4 4.6 4 1 0 4 4 4 2 HAMP domain TarH PF02203.15 AAZ35910.1 - 1.1e-12 48.3 0.2 1.1e-12 48.3 0.2 3.5 4 1 0 4 4 4 1 Tar ligand binding domain homologue AI-2E_transport PF01594.16 AAZ35910.1 - 0.013 14.6 1.2 2.5 7.2 0.0 2.5 2 1 0 2 2 2 0 AI-2E family transporter DUF1517 PF07466.11 AAZ35910.1 - 0.024 14.8 6.1 0.094 12.8 6.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) IFT57 PF10498.9 AAZ35910.1 - 0.085 11.8 6.2 0.038 12.9 0.7 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 UPF0242 PF06785.11 AAZ35910.1 - 0.085 12.9 0.8 7.5 6.6 0.0 3.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus BORCS6 PF10157.9 AAZ35910.1 - 0.17 12.1 9.5 0.048 13.9 2.9 2.9 2 1 1 3 3 3 0 BLOC-1-related complex sub-unit 6 AAA_13 PF13166.6 AAZ35910.1 - 0.21 10.2 12.5 0.011 14.4 3.9 2.1 1 1 0 2 2 2 0 AAA domain KxDL PF10241.9 AAZ35910.1 - 0.26 11.6 5.5 0.81 10.0 1.4 3.3 3 0 0 3 3 2 0 Uncharacterized conserved protein Fib_alpha PF08702.10 AAZ35910.1 - 1.1 9.4 9.2 1.3 9.2 1.5 3.6 3 2 0 4 4 3 0 Fibrinogen alpha/beta chain family DUF948 PF06103.11 AAZ35910.1 - 1.5 9.1 26.2 0.78 10.0 6.9 5.0 2 1 3 5 5 4 0 Bacterial protein of unknown function (DUF948) Golgin_A5 PF09787.9 AAZ35910.1 - 1.8 8.0 7.1 0.63 9.4 1.6 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 5 DUF1043 PF06295.12 AAZ35910.1 - 1.8 8.6 5.8 22 5.1 0.9 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Sec34 PF04136.15 AAZ35910.1 - 2.5 8.0 8.7 0.66 9.8 1.6 3.0 3 0 0 3 3 3 0 Sec34-like family DUF1664 PF07889.12 AAZ35910.1 - 2.6 8.1 13.4 0.14 12.2 3.1 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 AAZ35910.1 - 3.1 8.1 7.8 4.4 7.7 1.4 3.5 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG6_N PF17675.1 AAZ35910.1 - 4 8.0 7.8 8.9 6.9 1.2 2.5 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF724 PF05266.14 AAZ35910.1 - 5.1 6.9 5.2 32 4.3 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Spc7 PF08317.11 AAZ35910.1 - 8.2 5.2 10.1 0.5 9.2 3.3 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Fez1 PF06818.15 AAZ35910.1 - 8.9 6.7 9.2 0.84 10.1 2.8 2.2 1 1 0 2 2 2 0 Fez1 CopD PF05425.13 AAZ35911.1 - 3.9e-18 65.8 8.9 3.9e-18 65.8 8.9 2.0 1 1 1 2 2 2 1 Copper resistance protein D DUF2269 PF10027.9 AAZ35911.1 - 2.3e-07 31.0 12.9 2.9e-07 30.6 12.9 1.2 1 0 0 1 1 1 1 Predicted integral membrane protein (DUF2269) DUF5362 PF17319.2 AAZ35911.1 - 0.0027 17.5 1.5 0.0054 16.5 1.4 1.6 1 1 0 1 1 1 1 Family of unknown function (DUF5362) DUF4149 PF13664.6 AAZ35911.1 - 0.012 15.9 8.3 0.012 15.9 8.3 1.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) Glyco_hydro_32N PF00251.20 AAZ35912.1 - 1.1e-101 340.4 0.0 1.4e-101 340.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 AAZ35912.1 - 2.4e-25 89.3 0.0 3.3e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_43 PF04616.14 AAZ35912.1 - 0.0022 17.3 0.0 0.031 13.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 Nramp PF01566.18 AAZ35913.1 - 1.6e-20 73.4 28.6 2.5e-20 72.8 28.6 1.3 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Toprim_N PF08275.11 AAZ35914.1 - 2.5e-44 150.4 0.0 4.5e-44 149.6 0.0 1.4 1 0 0 1 1 1 1 DNA primase catalytic core, N-terminal domain zf-CHC2 PF01807.20 AAZ35914.1 - 9.6e-42 140.8 0.0 1.8e-41 139.9 0.0 1.5 1 0 0 1 1 1 1 CHC2 zinc finger DnaG_DnaB_bind PF08278.11 AAZ35914.1 - 4.6e-27 95.1 13.5 1e-26 93.9 13.5 1.6 1 0 0 1 1 1 1 DNA primase DnaG DnaB-binding Toprim_4 PF13662.6 AAZ35914.1 - 1.1e-16 61.1 0.0 2.4e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 Toprim domain Toprim_2 PF13155.6 AAZ35914.1 - 5.4e-15 55.6 0.0 1.2e-14 54.5 0.0 1.7 1 0 0 1 1 1 1 Toprim-like Toprim PF01751.22 AAZ35914.1 - 2.1e-09 37.5 0.0 5.2e-09 36.2 0.0 1.7 2 0 0 2 2 2 1 Toprim domain Toprim_3 PF13362.6 AAZ35914.1 - 1e-08 35.4 0.0 2.1e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Toprim domain DnaB_bind PF10410.9 AAZ35914.1 - 1.4e-07 31.6 0.1 7.2e-07 29.3 0.0 2.3 3 0 0 3 3 3 1 DnaB-helicase binding domain of primase Perilipin PF03036.16 AAZ35914.1 - 0.061 12.4 0.5 0.13 11.3 0.5 1.5 1 0 0 1 1 1 0 Perilipin family HTH_6 PF01418.17 AAZ35915.1 - 1.1e-27 95.8 0.1 2.2e-27 94.8 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain, rpiR family SIS PF01380.22 AAZ35915.1 - 4e-19 68.8 0.6 8e-19 67.8 0.6 1.5 1 0 0 1 1 1 1 SIS domain SIS_2 PF13580.6 AAZ35915.1 - 2.2e-05 24.5 2.3 0.0013 18.8 0.1 3.0 1 1 2 3 3 3 1 SIS domain HTH_IclR PF09339.10 AAZ35915.1 - 0.027 14.3 0.6 0.12 12.2 0.0 2.4 3 0 0 3 3 3 0 IclR helix-turn-helix domain HTH_23 PF13384.6 AAZ35915.1 - 0.031 14.1 0.0 0.14 12.0 0.0 2.1 2 0 0 2 2 2 0 Homeodomain-like domain HTH_AsnC-type PF13404.6 AAZ35915.1 - 0.035 13.9 0.1 0.11 12.4 0.1 1.8 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_31 PF13560.6 AAZ35915.1 - 0.15 12.4 1.4 0.43 11.0 0.2 2.5 2 1 0 2 2 2 0 Helix-turn-helix domain Oxidored_molyb PF00174.19 AAZ35917.1 - 4.1e-31 107.9 0.0 6.4e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain TAT_signal PF10518.9 AAZ35917.1 - 0.19 11.7 4.9 0.31 11.0 4.9 1.4 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence ABC_tran PF00005.27 AAZ35918.1 - 1e-29 103.8 0.0 1.4e-29 103.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAZ35918.1 - 3.6e-10 40.2 0.0 0.00021 21.2 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAZ35918.1 - 1.9e-08 34.0 0.4 9.2e-07 28.5 0.4 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AAZ35918.1 - 0.00024 21.5 0.1 0.00039 20.8 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AAZ35918.1 - 0.001 18.8 0.2 0.0027 17.4 0.1 1.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AAZ35918.1 - 0.0028 17.9 0.8 0.018 15.3 0.8 2.1 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AAZ35918.1 - 0.0095 15.9 0.1 0.015 15.2 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase ABC_ATPase PF09818.9 AAZ35918.1 - 0.013 14.3 1.5 2.6 6.8 0.1 2.8 2 1 0 2 2 2 0 Predicted ATPase of the ABC class NB-ARC PF00931.22 AAZ35918.1 - 0.015 14.5 0.1 0.14 11.3 0.1 1.9 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.6 AAZ35918.1 - 0.017 14.7 0.2 0.035 13.7 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AAZ35918.1 - 0.017 15.6 0.1 0.036 14.5 0.0 1.5 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.6 AAZ35918.1 - 0.023 14.9 0.0 0.032 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AAZ35918.1 - 0.023 14.4 0.1 0.059 13.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 AAZ35918.1 - 0.024 15.0 0.0 3.5 8.1 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 AAZ35918.1 - 0.03 13.9 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 AAZ35918.1 - 0.039 13.9 0.1 0.13 12.1 0.1 1.9 2 0 0 2 2 2 0 NACHT domain PduV-EutP PF10662.9 AAZ35918.1 - 0.039 13.7 0.1 0.65 9.7 0.1 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 AAZ35918.1 - 0.077 13.3 0.1 0.23 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 AAZ35918.1 - 0.091 12.5 0.0 0.22 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 AAZ35918.1 - 0.1 12.6 0.1 6 6.9 0.1 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 AAZ35918.1 - 0.11 12.7 0.3 1.8 8.9 0.3 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 AAZ35918.1 - 0.11 11.7 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin MobB PF03205.14 AAZ35918.1 - 0.12 12.3 0.1 0.29 11.0 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B G-alpha PF00503.20 AAZ35918.1 - 0.16 11.1 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit Sdh5 PF03937.16 AAZ35919.1 - 8.8e-23 80.1 1.4 1e-22 79.9 1.4 1.0 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase MRFAP1 PF15155.6 AAZ35919.1 - 0.039 14.5 0.1 0.11 13.0 0.1 1.7 1 1 0 1 1 1 0 MORF4 family-associated protein1 VEK-30 PF12107.8 AAZ35919.1 - 0.12 12.3 2.6 5.8 7.0 0.3 2.4 2 0 0 2 2 2 0 Plasminogen (Pg) ligand in fibrinolytic pathway Metal_resist PF13801.6 AAZ35920.1 - 0.05 13.8 5.4 0.62 10.3 1.5 2.8 2 1 1 3 3 3 0 Heavy-metal resistance DMPK_coil PF08826.10 AAZ35920.1 - 2.9 8.1 17.7 0.57 10.3 5.1 3.2 2 1 0 3 3 3 0 DMPK coiled coil domain like MFS_1 PF07690.16 AAZ35921.1 - 1.3e-43 149.3 45.7 1.3e-43 149.3 45.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AAZ35921.1 - 1.3e-26 93.5 31.5 2.3e-25 89.4 6.0 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 AAZ35921.1 - 8.4e-08 31.9 10.1 8.4e-08 31.9 10.1 2.2 1 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 AAZ35921.1 - 3.2 6.5 25.8 0.016 14.1 5.6 2.4 1 1 1 2 2 2 0 MFS_1 like family DUF2778 PF10908.8 AAZ35922.1 - 1.3e-32 112.6 0.0 1.6e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2778) UvrD-helicase PF00580.21 AAZ35923.1 - 1.6e-19 70.6 0.0 3.1e-11 43.4 0.0 2.4 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 AAZ35923.1 - 1.4e-12 48.2 0.0 3.7e-05 24.1 0.0 2.8 3 1 0 3 3 3 2 AAA domain UvrD_C PF13361.6 AAZ35923.1 - 1.3e-09 37.9 0.0 3e-06 26.9 0.0 2.2 1 1 1 2 2 2 2 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 AAZ35923.1 - 5e-08 32.6 0.5 0.0011 18.8 0.2 2.6 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 AAZ35923.1 - 0.015 15.6 0.2 36 4.6 0.0 3.4 3 0 0 3 3 3 0 AAA domain TatD_DNase PF01026.21 AAZ35924.1 - 6.1e-66 222.4 0.0 6.9e-66 222.2 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Amidohydro_1 PF01979.20 AAZ35924.1 - 0.12 11.7 0.1 7.4 5.8 0.0 2.3 2 1 0 2 2 2 0 Amidohydrolase family APH PF01636.23 AAZ35924.1 - 0.71 9.7 6.7 1.1 9.1 3.2 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family RHS_repeat PF05593.14 AAZ35925.1 - 3.5e-43 145.5 68.7 2.6e-07 31.0 0.6 16.7 16 2 2 18 18 18 12 RHS Repeat RHS PF03527.14 AAZ35925.1 - 2.4e-20 72.0 5.6 5.1e-19 67.7 0.2 4.1 4 0 0 4 4 4 1 RHS protein PAAR_motif PF05488.13 AAZ35925.1 - 1.2e-15 57.4 2.4 1.4e-14 54.0 0.5 2.1 1 1 1 2 2 2 2 PAAR motif OCRE PF17780.1 AAZ35925.1 - 4 7.5 6.5 8 6.6 1.7 4.2 3 1 0 3 3 3 0 OCRE domain Pec_lyase_C PF00544.19 AAZ35927.1 - 6.1e-11 42.3 3.6 2.2e-09 37.2 3.6 2.2 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 AAZ35927.1 - 8.5e-07 28.9 1.8 0.12 12.3 0.1 2.1 1 1 0 1 1 1 1 Right handed beta helix region LmjF365940-deam PF14421.6 AAZ35928.1 - 0.1 12.2 0.0 0.12 12.0 0.0 1.0 1 0 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases Biotin_lipoyl_2 PF13533.6 AAZ35929.1 - 3.2e-18 65.3 2.5 7.6e-18 64.1 2.1 1.8 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 AAZ35929.1 - 6.7e-15 55.7 0.3 4.7e-10 40.1 0.0 2.5 2 1 0 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 AAZ35929.1 - 6.3e-12 45.2 0.4 1e-11 44.5 0.4 1.2 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD PF00529.20 AAZ35929.1 - 1.4e-05 24.9 0.0 2.7e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS CoA_binding_3 PF13727.6 AAZ35929.1 - 0.011 15.8 1.2 0.076 13.0 0.4 2.2 2 0 0 2 2 2 0 CoA-binding domain Biotin_lipoyl PF00364.22 AAZ35929.1 - 0.068 13.0 0.1 0.25 11.2 0.1 1.8 2 0 0 2 2 2 0 Biotin-requiring enzyme HlyD_2 PF12700.7 AAZ35929.1 - 0.12 11.1 0.0 0.35 9.5 0.0 1.6 2 0 0 2 2 2 0 HlyD family secretion protein CTV_P33 PF07184.11 AAZ35929.1 - 0.12 11.4 0.0 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 Citrus tristeza virus P33 protein VPS13_mid_rpt PF16910.5 AAZ35929.1 - 0.21 11.0 0.0 0.51 9.7 0.0 1.5 1 1 0 1 1 1 0 Repeating coiled region of VPS13 YCII PF03795.14 AAZ35930.1 - 4.7e-28 97.4 0.0 5.2e-28 97.3 0.0 1.0 1 0 0 1 1 1 1 YCII-related domain DUF1330 PF07045.11 AAZ35930.1 - 0.068 13.5 0.2 0.093 13.1 0.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1330) ABC_tran PF00005.27 AAZ35931.1 - 6.2e-29 101.3 0.0 8.4e-29 100.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 AAZ35931.1 - 5.2e-14 52.5 0.1 9.7e-14 51.6 0.1 1.5 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 AAZ35931.1 - 3.7e-07 30.3 0.3 0.00015 21.7 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAZ35931.1 - 2.4e-05 23.9 0.4 5.3e-05 22.7 0.4 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AAZ35931.1 - 3.1e-05 24.3 0.7 0.0015 18.8 0.7 2.2 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 AAZ35931.1 - 0.0022 16.9 0.4 0.019 13.8 0.1 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_16 PF13191.6 AAZ35931.1 - 0.0065 16.9 0.3 0.019 15.4 0.3 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AAZ35931.1 - 0.0072 16.0 0.3 0.014 15.1 0.3 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 AAZ35931.1 - 0.034 13.5 0.2 0.061 12.7 0.2 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_7 PF12775.7 AAZ35931.1 - 0.077 12.5 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Pox_A32 PF04665.12 AAZ35931.1 - 0.13 11.7 0.6 3 7.2 0.1 2.1 2 0 0 2 2 2 0 Poxvirus A32 protein DUF87 PF01935.17 AAZ35931.1 - 0.16 12.1 0.9 0.26 11.3 0.2 1.6 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_15 PF13175.6 AAZ35931.1 - 0.36 10.5 0.4 7.1 6.2 0.0 2.0 1 1 0 2 2 2 0 AAA ATPase domain LysR_substrate PF03466.20 AAZ35932.1 - 1.1e-39 136.0 1.8 1.5e-39 135.5 1.8 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ35932.1 - 4.4e-15 55.4 0.0 7.1e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family GDP_Man_Dehyd PF16363.5 AAZ35933.1 - 9.5e-35 120.6 0.0 5.5e-34 118.0 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 AAZ35933.1 - 3.7e-29 101.9 0.0 4.4e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 AAZ35933.1 - 3.8e-14 52.5 0.0 3.2e-13 49.5 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 AAZ35933.1 - 2e-10 40.3 0.0 2.6e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 AAZ35933.1 - 6.2e-09 35.3 0.0 7.5e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 AAZ35933.1 - 8.4e-07 28.4 0.8 1.2e-06 27.9 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein Oxidored_nitro PF00148.19 AAZ35933.1 - 0.0032 16.3 0.0 0.0049 15.7 0.0 1.3 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase NAD_binding_10 PF13460.6 AAZ35933.1 - 0.025 14.5 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding adh_short PF00106.25 AAZ35933.1 - 0.038 13.5 0.0 8.1 5.8 0.0 2.3 2 0 0 2 2 2 0 short chain dehydrogenase Glycos_transf_1 PF00534.20 AAZ35934.1 - 4.9e-28 97.8 0.0 1.2e-27 96.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAZ35934.1 - 1e-25 90.7 0.1 3.2e-25 89.1 0.1 1.8 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 AAZ35934.1 - 1.2e-24 87.2 0.0 3e-24 86.0 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 AAZ35934.1 - 6.3e-13 49.5 2.1 6.3e-13 49.5 2.1 2.4 3 0 0 3 3 3 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 AAZ35934.1 - 1.2e-06 28.8 0.1 2.1e-06 28.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 AAZ35934.1 - 0.00017 21.6 0.0 0.00034 20.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Erythro-docking PF09277.11 AAZ35934.1 - 0.068 13.1 0.2 0.2 11.6 0.2 1.8 1 0 0 1 1 1 0 Erythronolide synthase, docking Peripla_BP_6 PF13458.6 AAZ35934.1 - 0.084 12.5 0.0 0.2 11.3 0.0 1.6 2 0 0 2 2 2 0 Periplasmic binding protein BPD_transp_1 PF00528.22 AAZ35935.1 - 6.2e-13 48.9 14.9 6.2e-13 48.9 14.9 2.2 1 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component NapE PF06796.11 AAZ35935.1 - 6.4 6.4 8.1 0.72 9.4 2.9 2.1 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE 4HBT PF03061.22 AAZ35937.1 - 9.6e-17 61.1 0.0 1.5e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 AAZ35937.1 - 1.7e-10 41.5 0.0 2e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 AAZ35937.1 - 0.00015 21.1 0.0 0.00016 21.0 0.0 1.0 1 0 0 1 1 1 1 Acyl-ACP thioesterase TraI_2 PF07514.11 AAZ35938.1 - 8.9e-31 107.0 0.2 1.5e-30 106.2 0.2 1.3 1 0 0 1 1 1 1 Putative helicase Phage_integrase PF00589.22 AAZ35938.1 - 1.1e-22 80.6 0.4 2.7e-22 79.4 0.2 1.8 1 1 0 1 1 1 1 Phage integrase family Pur_DNA_glyco PF02245.16 AAZ35939.1 - 5.7e-35 120.3 0.0 6.6e-35 120.1 0.0 1.0 1 0 0 1 1 1 1 Methylpurine-DNA glycosylase (MPG) PGM_PMM_III PF02880.16 AAZ35939.1 - 0.039 14.1 0.0 0.063 13.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III BPD_transp_1 PF00528.22 AAZ35940.1 - 2.9e-18 66.3 11.1 2.9e-18 66.3 11.1 1.6 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component PhaC_N PF07167.13 AAZ35941.1 - 2.1e-64 216.3 0.0 4.1e-64 215.4 0.0 1.5 1 0 0 1 1 1 1 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus Abhydrolase_1 PF00561.20 AAZ35941.1 - 1e-25 90.8 0.0 1.5e-25 90.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold HATPase_c PF02518.26 AAZ35943.1 - 1.3e-25 90.1 0.0 2.9e-25 89.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CHASE3 PF05227.13 AAZ35943.1 - 3e-20 72.5 5.7 1.1e-19 70.7 5.7 2.0 1 0 0 1 1 1 1 CHASE3 domain Response_reg PF00072.24 AAZ35943.1 - 7.5e-18 64.7 0.1 1.9e-17 63.4 0.0 1.8 2 0 0 2 2 1 1 Response regulator receiver domain HisKA PF00512.25 AAZ35943.1 - 1.6e-17 63.3 2.5 4.7e-17 61.8 0.3 2.9 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 AAZ35943.1 - 1.6e-12 47.6 0.0 3.5e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 AAZ35943.1 - 7.1e-11 42.1 0.1 3.7e-10 39.8 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 AAZ35943.1 - 1.2e-07 32.0 0.0 3e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 AAZ35943.1 - 1.2e-06 28.7 0.1 2.4e-06 27.7 0.1 1.5 1 0 0 1 1 1 1 PAS fold HATPase_c_2 PF13581.6 AAZ35943.1 - 6.2e-05 23.0 0.0 0.00018 21.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain PAS_8 PF13188.7 AAZ35943.1 - 0.0013 18.7 0.0 0.0042 17.1 0.0 1.9 1 0 0 1 1 1 1 PAS domain HATPase_c_3 PF13589.6 AAZ35943.1 - 0.018 14.9 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Med25_NR-box PF11244.8 AAZ35943.1 - 0.076 13.4 1.2 0.58 10.6 0.2 2.6 2 0 0 2 2 2 0 Mediator complex subunit 25 C-terminal NR box-containing GNVR PF13807.6 AAZ35944.1 - 8.2e-29 99.4 2.8 8.2e-29 99.4 2.8 2.8 3 0 0 3 3 3 1 G-rich domain on putative tyrosine kinase Wzz PF02706.15 AAZ35944.1 - 4.7e-17 62.1 5.3 7.3e-17 61.5 0.1 2.6 2 0 0 2 2 2 1 Chain length determinant protein AAA_31 PF13614.6 AAZ35944.1 - 4.2e-10 39.8 0.0 1.5e-09 38.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 AAZ35944.1 - 2.5e-09 37.2 0.1 9.8e-09 35.3 0.0 2.1 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 AAZ35944.1 - 3.9e-08 33.1 0.0 7.7e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase MipZ PF09140.11 AAZ35944.1 - 2.3e-05 23.8 0.0 5.7e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 ATPase MipZ Occludin_ELL PF07303.13 AAZ35944.1 - 0.0017 19.1 2.4 0.13 13.0 0.2 2.5 2 0 0 2 2 2 1 Occludin homology domain AAA_26 PF13500.6 AAZ35944.1 - 0.0057 16.5 0.1 1 9.1 0.1 2.6 2 0 0 2 2 2 1 AAA domain CBP_BcsQ PF06564.12 AAZ35944.1 - 0.012 15.1 0.1 0.028 13.9 0.0 1.6 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 AAZ35944.1 - 0.018 14.5 0.1 0.059 12.8 0.0 1.9 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Prefoldin_2 PF01920.20 AAZ35944.1 - 0.055 13.4 6.7 0.4 10.7 0.1 2.6 2 0 0 2 2 2 0 Prefoldin subunit AAA_25 PF13481.6 AAZ35944.1 - 0.06 12.9 0.2 0.36 10.4 0.0 2.3 2 1 0 2 2 2 0 AAA domain DUF4140 PF13600.6 AAZ35944.1 - 0.23 11.9 4.2 12 6.4 0.1 2.7 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) UPF0449 PF15136.6 AAZ35944.1 - 1.4 9.4 5.8 18 5.9 1.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 FKBP_C PF00254.28 AAZ35945.1 - 3e-26 91.6 0.0 6.7e-26 90.5 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N PF01346.18 AAZ35945.1 - 4.6e-22 78.8 0.0 6.2e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Haemagg_act PF05860.13 AAZ35946.1 - 8.1e-34 116.1 8.6 8.1e-34 116.1 8.6 4.8 2 1 2 4 4 4 1 haemagglutination activity domain Fil_haemagg PF05594.14 AAZ35946.1 - 3.8e-15 56.2 336.3 5.7e-05 23.6 12.0 24.1 8 4 11 19 19 19 13 Haemagluttinin repeat HTH_3 PF01381.22 AAZ35947.1 - 8.2e-12 45.0 0.1 2.1e-11 43.7 0.1 1.7 2 0 0 2 2 2 1 Helix-turn-helix Cupin_2 PF07883.11 AAZ35947.1 - 2.6e-10 39.9 0.0 4.4e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Cupin domain HTH_31 PF13560.6 AAZ35947.1 - 1.9e-09 37.7 0.7 3.6e-09 36.8 0.7 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 AAZ35947.1 - 6.7e-07 29.2 0.0 1.1e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 AAZ35947.1 - 8.5e-06 26.1 0.0 1.5e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain AraC_binding PF02311.19 AAZ35947.1 - 0.0057 16.6 0.0 0.0098 15.8 0.0 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain HTH_37 PF13744.6 AAZ35947.1 - 0.0094 15.9 0.2 0.017 15.1 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 AAZ35947.1 - 0.011 15.6 0.3 0.32 10.9 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_24 PF13412.6 AAZ35947.1 - 0.11 12.0 0.0 0.28 10.8 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Cupin_1 PF00190.22 AAZ35947.1 - 0.17 11.5 0.0 0.46 10.1 0.0 1.6 2 0 0 2 2 2 0 Cupin Aldedh PF00171.22 AAZ35948.1 - 3.8e-154 513.6 0.1 4.3e-154 513.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MatE PF01554.18 AAZ35949.1 - 9.6e-21 74.1 40.7 2.2e-12 47.0 15.4 2.9 3 1 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 AAZ35949.1 - 6.6e-06 26.2 12.4 6.6e-06 26.2 12.4 4.9 2 2 3 5 5 5 1 Polysaccharide biosynthesis C-terminal domain ABC_tran PF00005.27 AAZ35950.1 - 2.3e-42 144.8 0.0 1e-24 87.6 0.0 2.2 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 AAZ35950.1 - 0.0052 16.3 0.1 0.26 10.7 0.0 2.7 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 AAZ35950.1 - 0.0052 16.7 0.1 0.16 11.9 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 AAZ35950.1 - 0.0074 16.1 0.1 0.1 12.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AAZ35950.1 - 0.048 13.4 0.5 0.13 12.0 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain Hid1 PF12722.7 AAZ35950.1 - 0.12 10.5 0.0 0.16 10.1 0.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein IstB_IS21 PF01695.17 AAZ35950.1 - 0.42 10.3 5.2 4.7 6.9 0.3 3.4 4 1 1 5 5 5 0 IstB-like ATP binding protein Pantoate_transf PF02548.15 AAZ35951.1 - 2e-102 342.0 5.4 2.3e-102 341.9 5.4 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase Asp_Glu_race PF01177.22 AAZ35951.1 - 0.00091 19.1 0.2 0.0028 17.5 0.1 1.8 2 0 0 2 2 2 1 Asp/Glu/Hydantoin racemase NanE PF04131.14 AAZ35951.1 - 0.077 12.2 2.6 0.12 11.5 0.2 2.3 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase Spermine_synth PF01564.17 AAZ35952.1 - 0.00042 19.8 0.0 0.00062 19.2 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain MTS PF05175.14 AAZ35952.1 - 0.063 12.8 0.1 0.65 9.5 0.1 2.1 1 1 0 1 1 1 0 Methyltransferase small domain RNase_E_G PF10150.9 AAZ35953.1 - 1.3e-102 342.8 0.1 1.8e-102 342.4 0.1 1.2 1 0 0 1 1 1 1 Ribonuclease E/G family S1 PF00575.23 AAZ35953.1 - 2.8e-08 34.0 0.1 8.9e-08 32.4 0.1 1.8 1 0 0 1 1 1 1 S1 RNA binding domain Biopterin_H PF00351.21 AAZ35954.1 - 3.7e-47 161.0 0.0 4.7e-47 160.6 0.0 1.0 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase DUF1780 PF08682.10 AAZ35955.1 - 2.9e-122 406.0 1.7 3.2e-122 405.9 1.7 1.0 1 0 0 1 1 1 1 Putative endonuclease, protein of unknown function (DUF1780) PfkB PF00294.24 AAZ35956.1 - 4.1e-49 167.5 0.3 5.2e-49 167.2 0.3 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase CTP_transf_like PF01467.26 AAZ35956.1 - 7.8e-15 55.3 0.0 1.5e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like Phos_pyr_kin PF08543.12 AAZ35956.1 - 3.8e-10 39.6 0.1 2.5e-09 36.9 0.0 2.0 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase FAD_syn PF06574.12 AAZ35956.1 - 0.046 13.6 0.1 0.16 11.9 0.0 2.0 2 0 0 2 2 2 0 FAD synthetase ATP-synt_C PF00137.21 AAZ35956.1 - 0.098 13.0 0.2 0.098 13.0 0.2 2.2 2 0 0 2 2 2 0 ATP synthase subunit C Abhydrolase_1 PF00561.20 AAZ35957.1 - 5.5e-28 98.3 0.1 1e-22 81.1 0.3 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAZ35957.1 - 5e-22 79.6 0.1 5.8e-22 79.4 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAZ35957.1 - 6.3e-22 78.0 0.0 7.8e-22 77.7 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 AAZ35957.1 - 0.00011 22.4 0.0 0.00011 22.4 0.0 1.3 1 1 0 1 1 1 1 Thioesterase domain Ndr PF03096.14 AAZ35957.1 - 0.0012 17.6 0.0 0.0019 17.0 0.0 1.3 1 0 0 1 1 1 1 Ndr family Palm_thioest PF02089.15 AAZ35957.1 - 0.0036 17.2 0.0 0.0044 16.9 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_2 PF02230.16 AAZ35957.1 - 0.007 16.2 0.4 1.1 9.0 0.1 2.3 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase PGAP1 PF07819.13 AAZ35957.1 - 0.042 13.6 0.4 8.4 6.0 0.0 2.3 1 1 1 2 2 2 0 PGAP1-like protein Abhydro_lipase PF04083.16 AAZ35957.1 - 0.067 12.8 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Peptidase_S15 PF02129.18 AAZ35957.1 - 0.16 11.6 0.0 0.29 10.7 0.0 1.7 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) PALP PF00291.25 AAZ35958.1 - 2e-44 152.2 0.1 2.2e-44 152.0 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme SdiA-regulated PF06977.11 AAZ35959.1 - 5.7e-99 330.4 0.0 6.7e-99 330.1 0.0 1.0 1 0 0 1 1 1 1 SdiA-regulated Phytase-like PF13449.6 AAZ35959.1 - 2.4e-10 40.8 0.1 1.5e-07 31.7 0.0 3.0 1 1 2 3 3 3 2 Esterase-like activity of phytase NHL PF01436.21 AAZ35959.1 - 0.00021 21.2 0.0 0.0035 17.3 0.0 2.4 2 0 0 2 2 2 1 NHL repeat DeoRC PF00455.22 AAZ35960.1 - 7.2e-43 146.3 0.0 9.3e-43 145.9 0.0 1.1 1 0 0 1 1 1 1 DeoR C terminal sensor domain HTH_DeoR PF08220.12 AAZ35960.1 - 8.8e-16 57.4 0.0 1.7e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 AAZ35960.1 - 1.8e-08 34.2 0.1 3.7e-08 33.2 0.1 1.5 1 0 0 1 1 1 1 HTH domain MarR PF01047.22 AAZ35960.1 - 0.00015 21.7 0.3 0.00049 20.0 0.0 2.0 2 0 0 2 2 2 1 MarR family GntR PF00392.21 AAZ35960.1 - 0.00018 21.1 0.2 0.0015 18.2 0.1 2.3 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_Mga PF08280.11 AAZ35960.1 - 0.00055 19.9 0.1 0.0016 18.5 0.0 1.7 2 0 0 2 2 2 1 M protein trans-acting positive regulator (MGA) HTH domain HTH_5 PF01022.20 AAZ35960.1 - 0.00068 19.5 0.0 0.0018 18.1 0.0 1.7 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family Rrf2 PF02082.20 AAZ35960.1 - 0.0051 17.1 0.1 0.014 15.7 0.0 1.7 2 0 0 2 2 2 1 Transcriptional regulator HTH_20 PF12840.7 AAZ35960.1 - 0.0078 16.3 0.2 0.019 15.0 0.2 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain Put_DNA-bind_N PF06971.13 AAZ35960.1 - 0.016 15.2 0.0 0.037 14.0 0.0 1.7 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus HTH_36 PF13730.6 AAZ35960.1 - 0.025 14.5 0.0 0.068 13.1 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain FeoC PF09012.10 AAZ35960.1 - 0.042 13.9 0.0 0.071 13.2 0.0 1.3 1 0 0 1 1 1 0 FeoC like transcriptional regulator DprA_WH PF17782.1 AAZ35960.1 - 0.07 13.2 1.5 0.33 11.1 0.0 2.6 3 0 0 3 3 3 0 DprA winged helix domain TrmB PF01978.19 AAZ35960.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Thioredoxin_7 PF13899.6 AAZ35960.1 - 0.12 12.6 0.0 0.5 10.6 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin-like Ribosomal_L14 PF00238.19 AAZ35961.1 - 5.4e-55 184.7 1.3 5.9e-55 184.6 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e PrmA PF06325.13 AAZ35962.1 - 3.6e-14 52.9 0.0 4.7e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 AAZ35962.1 - 8.7e-11 41.9 0.0 2.1e-10 40.6 0.0 1.5 1 1 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 AAZ35962.1 - 2.3e-08 33.8 0.0 3.6e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 AAZ35962.1 - 4.9e-07 30.4 0.1 9.3e-07 29.5 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAZ35962.1 - 2.4e-06 27.4 0.1 3.2e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 AAZ35962.1 - 2.3e-05 24.1 0.0 3.6e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_23 PF13489.6 AAZ35962.1 - 3.3e-05 23.8 0.0 4.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAZ35962.1 - 9.4e-05 23.1 0.1 0.00015 22.4 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAZ35962.1 - 0.00071 20.2 0.1 0.0012 19.4 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 AAZ35962.1 - 0.002 17.9 0.0 0.0027 17.5 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.16 AAZ35962.1 - 0.067 12.3 0.0 0.086 12.0 0.0 1.1 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase ABC_transp_aux PF09822.9 AAZ35962.1 - 0.14 11.6 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 ABC-type uncharacterized transport system Methyltransf_9 PF08003.11 AAZ35962.1 - 0.16 10.9 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Na_Pi_cotrans PF02690.15 AAZ35963.1 - 1.2e-42 145.3 24.9 7.5e-34 116.8 13.4 2.3 2 0 0 2 2 2 2 Na+/Pi-cotransporter PhoU PF01895.19 AAZ35963.1 - 1.8e-08 34.7 5.9 3.8e-06 27.3 1.0 2.5 2 0 0 2 2 2 2 PhoU domain Snf7 PF03357.21 AAZ35963.1 - 0.12 11.9 0.7 0.24 11.0 0.4 1.6 2 0 0 2 2 2 0 Snf7 YfiO PF13525.6 AAZ35965.1 - 1.4e-76 256.7 7.4 1.8e-76 256.4 6.3 1.6 1 1 1 2 2 2 1 Outer membrane lipoprotein TPR_18 PF13512.6 AAZ35965.1 - 1.7e-50 170.9 3.4 1.7e-50 170.9 3.4 2.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 AAZ35965.1 - 9.5e-06 25.9 8.6 0.021 15.4 0.1 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_21 PF09976.9 AAZ35965.1 - 0.0008 19.2 0.4 0.0008 19.2 0.4 1.9 3 0 0 3 3 3 1 Tetratricopeptide repeat-like domain TPR_16 PF13432.6 AAZ35965.1 - 0.0031 18.1 5.5 0.0058 17.3 0.1 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 AAZ35965.1 - 0.069 14.0 0.5 0.84 10.6 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat LysR_substrate PF03466.20 AAZ35966.1 - 3.6e-50 170.2 0.3 6e-50 169.5 0.3 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ35966.1 - 1.4e-20 72.9 1.4 2.4e-20 72.3 0.9 1.7 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family Ivy PF08816.11 AAZ35967.1 - 2.2e-42 143.9 0.0 2.7e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 Inhibitor of vertebrate lysozyme (Ivy) MFS_1 PF07690.16 AAZ35968.1 - 0.015 14.3 0.8 0.017 14.0 0.8 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily Acetyltransf_10 PF13673.7 AAZ35969.1 - 4.1e-12 46.2 0.0 1.1e-11 44.8 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAZ35969.1 - 1.2e-09 38.4 0.0 1.9e-09 37.8 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAZ35969.1 - 2.8e-09 37.3 0.0 9.4e-09 35.6 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAZ35969.1 - 2e-05 24.4 0.6 0.00039 20.3 0.1 2.7 2 1 0 3 3 3 1 FR47-like protein PanZ PF12568.8 AAZ35969.1 - 0.0029 17.3 0.0 0.0039 16.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_CG PF14542.6 AAZ35969.1 - 0.023 14.8 0.0 0.054 13.6 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 AAZ35969.1 - 0.075 13.7 0.0 0.083 13.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 AAZ35969.1 - 0.11 12.5 0.0 1.9 8.5 0.0 2.2 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase Glycos_transf_2 PF00535.26 AAZ35970.1 - 1e-16 61.2 0.0 1.6e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAZ35970.1 - 9.5e-07 28.9 0.0 1.3e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 AAZ35970.1 - 3e-05 23.6 0.0 4.4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AAZ35970.1 - 0.0087 16.6 0.0 0.017 15.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 2 RIX1 PF08167.12 AAZ35970.1 - 0.093 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis SBP_bac_5 PF00496.22 AAZ35971.1 - 1.1e-87 294.5 0.8 1.4e-87 294.2 0.8 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle OpuAC PF04069.12 AAZ35971.1 - 0.004 16.8 0.1 0.018 14.7 0.0 2.1 2 0 0 2 2 2 1 Substrate binding domain of ABC-type glycine betaine transport system PD40 PF07676.12 AAZ35971.1 - 0.025 14.5 0.0 0.098 12.6 0.0 2.0 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat DUF4194 PF13835.6 AAZ35972.1 - 3.9e-05 23.5 0.3 6.2e-05 22.8 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4194) MukE PF04288.13 AAZ35972.1 - 0.011 14.7 0.1 0.022 13.7 0.1 1.5 1 0 0 1 1 1 0 MukE-like family Nif11 PF07862.11 AAZ35972.1 - 0.13 12.6 2.8 0.49 10.7 0.1 3.0 3 1 0 3 3 3 0 Nif11 domain AAA_2 PF07724.14 AAZ35973.1 - 1.5e-57 194.4 0.0 1.2e-54 184.9 0.0 3.2 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 AAZ35973.1 - 4.5e-35 119.7 6.6 4.5e-35 119.7 6.6 2.5 2 0 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 AAZ35973.1 - 7.3e-26 90.1 0.3 5.5e-25 87.2 0.0 2.8 3 0 0 3 3 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 AAZ35973.1 - 3.9e-25 88.8 0.2 1.7e-13 51.1 0.0 3.2 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) Clp_N PF02861.20 AAZ35973.1 - 2.3e-23 82.1 5.4 5.6e-11 42.4 0.7 3.1 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA_5 PF07728.14 AAZ35973.1 - 3.4e-18 66.0 1.2 8.5e-13 48.5 0.0 3.6 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AAZ35973.1 - 7.1e-10 39.5 9.3 0.00022 21.7 0.0 4.9 4 2 0 6 6 4 2 AAA ATPase domain AAA_22 PF13401.6 AAZ35973.1 - 6.9e-09 36.1 5.4 0.016 15.4 0.1 5.2 3 2 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 AAZ35973.1 - 1.6e-08 34.5 0.1 0.011 15.5 0.0 3.5 2 1 0 2 2 2 2 IstB-like ATP binding protein Sigma54_activat PF00158.26 AAZ35973.1 - 2.9e-08 33.6 0.1 0.00011 22.0 0.0 2.8 3 0 0 3 3 2 2 Sigma-54 interaction domain AAA_24 PF13479.6 AAZ35973.1 - 9.3e-06 25.5 0.1 0.018 14.8 0.0 3.1 3 1 0 3 3 2 2 AAA domain AAA_18 PF13238.6 AAZ35973.1 - 9.9e-06 26.1 3.3 0.047 14.2 0.0 3.7 3 2 0 3 3 2 2 AAA domain Mg_chelatase PF01078.21 AAZ35973.1 - 1.1e-05 24.9 0.2 0.82 9.0 0.0 3.9 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 AAZ35973.1 - 1.3e-05 25.2 3.8 0.23 11.4 0.0 4.4 3 2 1 4 4 4 1 ATPase domain predominantly from Archaea TniB PF05621.11 AAZ35973.1 - 2e-05 24.1 0.0 0.029 13.8 0.0 3.5 2 1 0 2 2 2 1 Bacterial TniB protein RuvB_N PF05496.12 AAZ35973.1 - 2.3e-05 24.2 0.3 3.9 7.2 0.0 4.5 4 0 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 AAZ35973.1 - 0.0001 21.9 0.0 0.11 12.0 0.0 2.7 3 0 0 3 3 2 1 P-loop containing dynein motor region AAA_14 PF13173.6 AAZ35973.1 - 0.00017 21.7 0.1 0.48 10.4 0.0 3.1 3 0 0 3 3 2 2 AAA domain Roc PF08477.13 AAZ35973.1 - 0.00029 21.1 0.0 0.43 10.8 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 AAZ35973.1 - 0.00029 21.2 0.0 1.1 9.7 0.0 2.8 2 0 0 2 2 2 2 RNA helicase RsgA_GTPase PF03193.16 AAZ35973.1 - 0.00048 20.1 0.0 1.6 8.6 0.0 3.5 3 0 0 3 3 3 1 RsgA GTPase ABC_tran PF00005.27 AAZ35973.1 - 0.0014 19.2 2.5 0.33 11.5 0.0 3.8 3 2 0 3 3 3 1 ABC transporter DNA_pol3_delta2 PF13177.6 AAZ35973.1 - 0.0017 18.2 0.0 4.4 7.1 0.0 3.3 3 0 0 3 3 3 0 DNA polymerase III, delta subunit TsaE PF02367.17 AAZ35973.1 - 0.0028 17.7 0.0 4.2 7.4 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 AAZ35973.1 - 0.0029 17.5 0.0 0.35 10.8 0.0 2.9 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.6 AAZ35973.1 - 0.003 17.9 0.1 0.56 10.5 0.1 3.4 3 1 0 3 3 2 1 AAA domain AAA_33 PF13671.6 AAZ35973.1 - 0.0038 17.4 0.0 4.4 7.5 0.0 3.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 AAZ35973.1 - 0.0052 16.1 0.0 2.3 7.4 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin DUF815 PF05673.13 AAZ35973.1 - 0.0053 15.9 0.1 2.9 7.0 0.1 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF815) ResIII PF04851.15 AAZ35973.1 - 0.0054 16.7 0.0 6.8 6.7 0.0 3.5 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_25 PF13481.6 AAZ35973.1 - 0.007 16.0 0.0 2.2 7.8 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_3 PF07726.11 AAZ35973.1 - 0.0074 16.1 0.1 3.6 7.4 0.0 3.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 AAZ35973.1 - 0.0078 16.5 4.4 3.4 7.9 0.0 4.2 5 1 1 6 6 3 1 AAA domain PduV-EutP PF10662.9 AAZ35973.1 - 0.01 15.6 0.0 0.37 10.5 0.0 2.8 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 AAZ35973.1 - 0.014 15.1 0.4 0.47 10.2 0.0 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein SRP54 PF00448.22 AAZ35973.1 - 0.031 13.9 0.1 1 9.0 0.0 2.9 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 AAZ35973.1 - 0.045 13.7 0.0 18 5.2 0.0 3.3 2 0 0 2 2 2 0 NTPase AAA_29 PF13555.6 AAZ35973.1 - 0.065 13.0 0.0 7.4 6.4 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_17 PF13207.6 AAZ35973.1 - 0.11 13.0 1.2 14 6.1 0.0 3.5 3 0 0 3 3 2 0 AAA domain AAA_23 PF13476.6 AAZ35973.1 - 4.5 7.7 0.0 4.5 7.7 0.0 4.4 2 1 0 2 2 1 0 AAA domain Atg14 PF10186.9 AAZ35973.1 - 7.7 5.5 8.3 15 4.6 8.3 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HAUS2 PF15003.6 AAZ35973.1 - 8.2 6.1 9.5 10 5.8 6.4 2.5 2 1 1 3 3 3 0 HAUS augmin-like complex subunit 2 DUF572 PF04502.13 AAZ35973.1 - 9.7 5.7 8.2 20 4.7 8.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) Autoind_bind PF03472.15 AAZ35974.1 - 1.5e-35 121.9 0.1 2.5e-35 121.2 0.1 1.4 1 0 0 1 1 1 1 Autoinducer binding domain GerE PF00196.19 AAZ35974.1 - 9.6e-20 69.9 0.4 1.7e-19 69.1 0.4 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AAZ35974.1 - 1.1e-06 28.2 0.1 2.1e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 AAZ35974.1 - 3.1e-05 23.6 0.2 7.1e-05 22.5 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 AAZ35974.1 - 3.7e-05 23.1 0.1 7.1e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 AAZ35974.1 - 0.0026 17.5 0.1 0.0056 16.4 0.1 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_24 PF13412.6 AAZ35974.1 - 0.0084 15.6 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 AAZ35974.1 - 0.0094 16.0 0.1 0.026 14.6 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_40 PF14493.6 AAZ35974.1 - 0.016 15.6 0.0 0.031 14.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_11 PF08279.12 AAZ35974.1 - 0.022 14.7 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 HTH domain HTH_10 PF04967.12 AAZ35974.1 - 0.044 13.6 0.3 0.15 11.9 0.1 2.1 2 0 0 2 2 2 0 HTH DNA binding domain MlaC PF05494.12 AAZ35975.1 - 1.6e-38 132.1 0.2 1.9e-38 131.9 0.2 1.0 1 0 0 1 1 1 1 MlaC protein DUF4878 PF12870.7 AAZ35975.1 - 8.6e-05 22.8 0.0 0.00018 21.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4878) NTP_transferase PF00483.23 AAZ35976.1 - 2.1e-20 73.3 0.0 3e-17 63.0 0.0 2.0 2 0 0 2 2 2 2 Nucleotidyl transferase NTP_transf_3 PF12804.7 AAZ35976.1 - 2.8e-13 50.5 0.0 4.5e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 AAZ35976.1 - 0.0053 16.5 0.0 0.0097 15.7 0.0 1.4 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase OxoDH_E1alpha_N PF12573.8 AAZ35976.1 - 0.12 12.2 1.7 11 5.9 0.8 2.5 2 0 0 2 2 2 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal FGGY_N PF00370.21 AAZ35977.1 - 1.9e-34 119.3 0.0 9.9e-34 117.0 0.0 1.9 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 AAZ35977.1 - 2.7e-29 102.3 0.3 7.1e-29 101.0 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Acyl_transf_1 PF00698.21 AAZ35978.1 - 3e-27 96.0 2.2 3.6e-27 95.7 2.2 1.0 1 0 0 1 1 1 1 Acyl transferase domain SAT PF16073.5 AAZ35978.1 - 0.00026 20.8 5.0 0.096 12.4 4.2 2.9 1 1 1 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis F_bP_aldolase PF01116.20 AAZ35978.1 - 0.063 12.7 0.6 0.093 12.2 0.6 1.2 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-II Penicil_amidase PF01804.18 AAZ35979.1 - 1e-138 464.3 1.0 1.2e-138 464.1 1.0 1.0 1 0 0 1 1 1 1 Penicillin amidase KdpC PF02669.15 AAZ35980.1 - 1.8e-62 210.4 0.5 2e-62 210.2 0.5 1.0 1 0 0 1 1 1 1 K+-transporting ATPase, c chain Acetyltransf_1 PF00583.25 AAZ35981.1 - 1.4e-10 41.4 0.0 1.7e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AAZ35981.1 - 2.7e-09 37.1 0.0 3.5e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAZ35981.1 - 1.5e-08 35.0 0.0 2.3e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 AAZ35981.1 - 0.0032 17.4 0.0 0.0071 16.3 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase FR47 PF08445.10 AAZ35981.1 - 0.03 14.3 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.6 AAZ35981.1 - 0.071 13.2 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Bac_export_1 PF01311.20 AAZ35982.1 - 1e-41 143.0 19.9 1.3e-41 142.7 19.9 1.0 1 0 0 1 1 1 1 Bacterial export proteins, family 1 2TM PF13239.6 AAZ35982.1 - 0.45 10.9 0.1 0.45 10.9 0.1 2.4 2 1 1 3 3 3 0 2TM domain DUF1449 PF07290.11 AAZ35982.1 - 0.8 9.3 11.9 0.21 11.2 6.9 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1449) DUF3742 PF12553.8 AAZ35982.1 - 5.6 7.1 6.3 25 5.0 2.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3742) ExbD PF02472.16 AAZ35983.1 - 2.5e-27 95.6 0.3 3e-27 95.4 0.3 1.1 1 0 0 1 1 1 1 Biopolymer transport protein ExbD/TolR DUF5127 PF17168.4 AAZ35983.1 - 0.051 13.4 0.2 0.061 13.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5127) CLZ PF16526.5 AAZ35983.1 - 0.092 13.1 0.1 0.17 12.3 0.1 1.4 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF2149 PF09919.9 AAZ35983.1 - 1.2 9.5 3.8 1.4 9.3 2.5 1.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2149) RskA PF10099.9 AAZ35984.1 - 1.1e-22 81.2 2.6 2e-22 80.3 2.6 1.4 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Sigma70_r2 PF04542.14 AAZ35984.1 - 1e-16 60.4 2.4 3.2e-16 58.8 1.2 2.3 2 0 0 2 2 2 1 Sigma-70 region 2 HTH_43 PF09904.9 AAZ35985.1 - 7.7e-40 134.7 0.0 8.6e-40 134.6 0.0 1.0 1 0 0 1 1 1 1 Winged helix-turn helix Phage_integrase PF00589.22 AAZ35986.1 - 1.4e-13 51.0 0.0 5.4e-13 49.1 0.0 2.0 1 1 0 1 1 1 1 Phage integrase family PRP38 PF03371.15 AAZ35986.1 - 0.034 14.0 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 PRP38 family Aldedh PF00171.22 AAZ35987.1 - 6.3e-175 582.1 0.0 7.1e-175 581.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 AAZ35987.1 - 0.011 15.2 0.0 0.11 11.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) GCV_T PF01571.21 AAZ35988.1 - 2.1e-73 246.9 0.0 3e-73 246.3 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain SO_alpha_A3 PF17806.1 AAZ35988.1 - 1.2e-32 112.0 0.0 3.2e-32 110.7 0.0 1.7 1 0 0 1 1 1 1 Sarcosine oxidase A3 domain Fer2_4 PF13510.6 AAZ35988.1 - 1.2e-23 83.0 0.0 2.7e-23 81.8 0.0 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain GCV_T_C PF08669.11 AAZ35988.1 - 2.1e-17 62.8 0.0 6.5e-17 61.2 0.0 1.9 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Pyr_redox_2 PF07992.14 AAZ35988.1 - 4.3e-10 39.3 0.0 6.9e-09 35.3 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AAZ35988.1 - 6.3e-09 35.7 1.0 1.1e-08 34.9 1.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AAZ35988.1 - 2.5e-08 33.4 3.2 1.7e-07 30.7 1.3 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 AAZ35988.1 - 3.9e-06 27.0 0.2 1.2e-05 25.4 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 AAZ35988.1 - 4e-06 25.8 0.5 7.4e-06 24.9 0.5 1.4 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 AAZ35988.1 - 1.6e-05 24.2 1.8 0.002 17.3 2.5 2.2 1 1 1 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 AAZ35988.1 - 3e-05 23.4 0.1 5.5e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 AAZ35988.1 - 3.7e-05 23.1 1.0 0.005 16.1 0.4 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 AAZ35988.1 - 0.00049 19.4 0.0 0.00099 18.4 0.0 1.5 1 0 0 1 1 1 1 Thi4 family SoxG PF04268.12 AAZ35988.1 - 0.00071 19.8 0.0 0.017 15.3 0.0 2.9 4 0 0 4 4 4 1 Sarcosine oxidase, gamma subunit family AlaDh_PNT_C PF01262.21 AAZ35988.1 - 0.00089 18.6 0.2 0.0022 17.3 0.2 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 AAZ35988.1 - 0.00089 19.8 0.1 0.41 11.2 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AAZ35988.1 - 0.0038 16.9 10.0 0.004 16.8 1.1 3.5 4 1 0 5 5 5 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 AAZ35988.1 - 0.15 11.1 1.2 0.43 9.6 1.2 1.8 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 AAZ35988.1 - 0.42 10.6 1.9 14 5.7 1.9 2.7 1 1 0 1 1 1 0 FAD-NAD(P)-binding GATase PF00117.28 AAZ35989.1 - 6.6e-56 189.1 0.1 7.3e-56 188.9 0.1 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AAZ35989.1 - 5.6e-11 42.6 0.3 1e-10 41.7 0.3 1.4 1 1 0 1 1 1 1 Peptidase C26 CopB PF05275.11 AAZ35990.1 - 2.7e-85 285.2 0.7 3.3e-85 284.9 0.7 1.1 1 0 0 1 1 1 1 Copper resistance protein B precursor (CopB) Autotransporter PF03797.19 AAZ35990.1 - 1.5e-05 24.8 3.4 0.00012 21.8 0.2 2.9 2 2 0 2 2 2 1 Autotransporter beta-domain OMP_b-brl PF13505.6 AAZ35990.1 - 0.0036 17.5 0.2 0.0057 16.8 0.2 1.4 1 0 0 1 1 1 1 Outer membrane protein beta-barrel domain BBP2_2 PF10082.9 AAZ35990.1 - 0.026 13.3 0.3 0.61 8.9 0.1 2.1 1 1 1 2 2 2 0 Putative beta-barrel porin 2 DUF2147 PF09917.9 AAZ35991.1 - 3e-17 63.3 0.4 4.8e-17 62.6 0.4 1.3 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2147) PilZ PF07238.14 AAZ35991.1 - 0.041 14.2 0.0 0.069 13.5 0.0 1.3 1 0 0 1 1 1 0 PilZ domain FliT PF05400.13 AAZ35992.1 - 1.3e-07 32.4 0.6 2e-07 31.7 0.3 1.5 1 1 1 2 2 2 1 Flagellar protein FliT MotA_ExbB PF01618.16 AAZ35993.1 - 2.2e-10 40.4 0.2 4.7e-10 39.3 0.2 1.6 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family PGF-CTERM PF18204.1 AAZ35993.1 - 1.3 9.1 9.0 0.14 12.2 2.5 2.8 2 1 0 2 2 2 0 PGF-CTERM motif DUF2104 PF09877.9 AAZ35993.1 - 2.9 8.2 11.4 1.1 9.5 1.5 2.6 2 1 0 2 2 2 0 Predicted membrane protein (DUF2104) Tyrosinase PF00264.20 AAZ35994.1 - 0.003 17.9 1.7 0.0047 17.2 1.7 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase TAT_signal PF10518.9 AAZ35994.1 - 0.13 12.2 1.2 0.29 11.1 1.2 1.6 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence CLCA PF08434.11 AAZ35994.1 - 0.18 11.1 0.1 0.26 10.6 0.1 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel N terminal CDP-OH_P_transf PF01066.21 AAZ35995.1 - 2.8e-06 28.0 0.4 2.8e-06 28.0 0.4 3.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase ATP-synt_8 PF00895.20 AAZ35995.1 - 0.0088 16.5 3.1 0.08 13.4 1.6 2.7 2 0 0 2 2 2 1 ATP synthase protein 8 Rsd_AlgQ PF04353.13 AAZ35996.1 - 1.5e-50 171.1 0.0 1.7e-50 170.9 0.0 1.0 1 0 0 1 1 1 1 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ TPR_4 PF07721.14 AAZ35996.1 - 0.23 12.2 0.7 0.23 12.2 0.7 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat LPAM_1 PF08139.12 AAZ35997.1 - 0.083 13.4 1.0 0.16 12.6 1.0 1.5 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site SoxD PF04267.12 AAZ35998.1 - 1.5e-35 121.1 0.5 1.8e-35 120.9 0.5 1.0 1 0 0 1 1 1 1 Sarcosine oxidase, delta subunit family zf-ribbon_3 PF13248.6 AAZ35998.1 - 0.038 13.4 0.0 0.066 12.7 0.0 1.4 1 0 0 1 1 1 0 zinc-ribbon domain adh_short PF00106.25 AAZ35999.1 - 4.2e-57 192.8 1.5 5e-57 192.5 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAZ35999.1 - 4.6e-56 190.0 1.4 5.3e-56 189.8 1.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAZ35999.1 - 3.6e-09 36.8 1.8 4.8e-09 36.4 1.8 1.1 1 0 0 1 1 1 1 KR domain Methyltransf_25 PF13649.6 AAZ35999.1 - 0.0047 17.6 0.5 0.011 16.4 0.4 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAZ35999.1 - 0.14 11.9 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain 3HCDH_N PF02737.18 AAZ35999.1 - 0.17 11.8 0.4 0.26 11.1 0.4 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PIN PF01850.21 AAZ36000.1 - 6.4e-12 46.1 0.1 8.6e-12 45.6 0.1 1.1 1 0 0 1 1 1 1 PIN domain DUF4411 PF14367.6 AAZ36000.1 - 0.027 14.4 0.1 0.065 13.1 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4411) Response_reg PF00072.24 AAZ36001.1 - 1.1e-22 80.3 0.3 1.2e-22 80.1 0.3 1.0 1 0 0 1 1 1 1 Response regulator receiver domain FleQ PF06490.11 AAZ36001.1 - 0.022 15.1 0.0 0.031 14.7 0.0 1.2 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ NLPC_P60 PF00877.19 AAZ36003.1 - 1e-30 105.8 0.0 1.3e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 NlpC/P60 family Peptidase_C92 PF05708.12 AAZ36003.1 - 0.00032 20.8 0.0 0.54 10.3 0.0 2.3 2 1 0 2 2 2 2 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family DUF1175 PF06672.11 AAZ36003.1 - 0.0061 16.3 0.0 1.2 8.8 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1175) Amidase_5 PF05382.13 AAZ36003.1 - 0.036 14.0 0.1 0.065 13.1 0.1 1.4 1 1 0 1 1 1 0 Bacteriophage peptidoglycan hydrolase LRAT PF04970.13 AAZ36003.1 - 0.062 13.6 0.0 0.084 13.2 0.0 1.2 1 0 0 1 1 1 0 Lecithin retinol acyltransferase Prot_ATP_OB_N PF17758.1 AAZ36003.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain Phage_pRha PF09669.10 AAZ36004.1 - 2.1e-16 60.3 0.0 2.6e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) HTH_Crp_2 PF13545.6 AAZ36004.1 - 0.0017 18.3 0.0 0.0028 17.6 0.0 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_24 PF13412.6 AAZ36004.1 - 0.012 15.1 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding TrmB PF01978.19 AAZ36004.1 - 0.027 14.4 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 AAZ36004.1 - 0.069 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 MarR family Rio2_N PF09202.11 AAZ36004.1 - 0.16 12.2 0.0 0.33 11.2 0.0 1.6 1 1 0 1 1 1 0 Rio2, N-terminal Aminotran_1_2 PF00155.21 AAZ36005.1 - 2.1e-60 204.8 0.0 2.4e-60 204.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 AAZ36005.1 - 3.1e-07 29.7 0.0 4.3e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 AAZ36005.1 - 0.00012 20.8 0.0 0.00017 20.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 AAZ36005.1 - 0.0011 18.4 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family OKR_DC_1 PF01276.20 AAZ36005.1 - 0.21 10.3 0.0 0.39 9.4 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain HTH_18 PF12833.7 AAZ36006.1 - 2.5e-21 75.7 1.0 2.5e-21 75.7 1.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain AraC_binding PF02311.19 AAZ36006.1 - 6.7e-18 64.9 0.1 1.5e-17 63.7 0.1 1.5 1 0 0 1 1 1 1 AraC-like ligand binding domain HTH_AraC PF00165.23 AAZ36006.1 - 2.3e-17 62.6 0.1 3.9e-08 33.2 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Cupin_2 PF07883.11 AAZ36006.1 - 0.046 13.4 0.0 0.077 12.7 0.0 1.4 1 0 0 1 1 1 0 Cupin domain SH3_3 PF08239.11 AAZ36007.1 - 9.3e-12 45.1 0.1 2.1e-11 43.9 0.1 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain Rick_17kDa_Anti PF05433.15 AAZ36007.1 - 0.0003 20.6 23.1 0.00058 19.7 23.1 1.5 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.6 AAZ36007.1 - 0.0027 17.4 16.6 0.0048 16.6 16.6 1.4 1 0 0 1 1 1 1 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 AAZ36007.1 - 0.0051 16.8 15.3 0.0051 16.8 15.3 1.8 2 0 0 2 2 2 1 Glycine zipper BetR PF08667.10 AAZ36007.1 - 0.097 12.7 0.1 0.69 9.9 0.1 2.0 2 0 0 2 2 2 0 BetR domain TraT PF05818.12 AAZ36007.1 - 0.48 10.1 5.6 0.79 9.4 5.6 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein DUF2007 PF09413.10 AAZ36008.1 - 3.3e-12 46.4 0.4 3.9e-12 46.2 0.4 1.1 1 0 0 1 1 1 1 Putative prokaryotic signal transducing protein RNase_H PF00075.24 AAZ36009.1 - 6.4e-49 165.8 0.0 7.2e-49 165.6 0.0 1.0 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 AAZ36009.1 - 0.12 12.2 0.2 1.8 8.4 0.2 2.5 1 1 0 1 1 1 0 Reverse transcriptase-like Glycos_transf_2 PF00535.26 AAZ36010.1 - 9.1e-33 113.4 0.0 1.7e-32 112.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAZ36010.1 - 5e-17 62.5 0.2 7.9e-17 61.9 0.2 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 AAZ36010.1 - 1.5e-07 31.1 0.0 2.2e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AAZ36010.1 - 0.00058 20.3 0.0 0.0012 19.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 AAZ36010.1 - 0.035 13.6 0.0 0.06 12.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 DUF2256 PF10013.9 AAZ36011.1 - 4.3e-23 81.2 11.6 4.8e-23 81.0 11.6 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-MYND PF01753.18 AAZ36011.1 - 0.0055 16.8 4.3 0.0076 16.3 4.3 1.3 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.7 AAZ36011.1 - 0.009 17.2 1.2 0.0091 17.2 1.2 1.1 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins DUF2116 PF09889.9 AAZ36011.1 - 0.47 10.5 4.4 4.7 7.3 4.4 2.1 1 1 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) ARD PF03079.14 AAZ36012.1 - 9e-37 126.7 0.0 1.1e-36 126.4 0.0 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 AAZ36012.1 - 2.4e-05 23.9 0.2 4.3e-05 23.1 0.2 1.4 1 0 0 1 1 1 1 Cupin domain POTRA_2 PF08479.11 AAZ36012.1 - 0.024 14.5 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 POTRA domain, ShlB-type DUF3526 PF12040.8 AAZ36012.1 - 0.13 12.8 0.0 0.18 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3526) BPD_transp_1 PF00528.22 AAZ36013.1 - 9.9e-17 61.3 16.3 9.9e-17 61.3 16.3 1.3 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component Aminotran_3 PF00202.21 AAZ36014.1 - 1.2e-134 449.0 0.4 1.3e-134 448.9 0.4 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 AAZ36014.1 - 0.00018 20.8 0.0 0.00062 19.0 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II GPW_gp25 PF04965.14 AAZ36015.1 - 1.3e-13 50.5 0.2 1.9e-13 50.0 0.2 1.2 1 0 0 1 1 1 1 Gene 25-like lysozyme EamA PF00892.20 AAZ36016.1 - 3.7e-23 82.2 36.6 1.8e-11 44.4 12.8 2.0 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.6 AAZ36016.1 - 0.012 15.2 12.4 0.036 13.6 12.4 1.8 1 1 0 1 1 1 0 Putative multidrug resistance efflux transporter DUF423 PF04241.15 AAZ36016.1 - 0.074 13.3 9.9 0.86 9.8 0.5 3.3 2 1 0 3 3 3 0 Protein of unknown function (DUF423) Pox_I5 PF04713.12 AAZ36016.1 - 0.23 11.5 10.0 0.85 9.7 0.1 3.9 4 1 1 5 5 5 0 Poxvirus protein I5 Trp_oprn_chp PF09534.10 AAZ36016.1 - 1.6 8.5 6.5 0.19 11.5 0.6 2.3 1 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) TPR_19 PF14559.6 AAZ36017.1 - 2e-07 31.4 8.6 0.00036 21.0 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 AAZ36017.1 - 0.00012 22.7 13.3 0.0024 18.5 0.0 4.2 4 0 0 4 4 3 2 Tetratricopeptide repeat LysM PF01476.20 AAZ36017.1 - 0.0084 16.2 0.0 0.023 14.7 0.0 1.8 1 1 0 1 1 1 1 LysM domain ERM PF00769.19 AAZ36017.1 - 0.018 14.9 1.5 0.018 14.9 1.5 1.7 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF641 PF04859.12 AAZ36017.1 - 0.018 15.4 1.6 0.041 14.2 1.6 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) FAM76 PF16046.5 AAZ36017.1 - 0.021 14.2 0.1 0.034 13.5 0.1 1.2 1 0 0 1 1 1 0 FAM76 protein TPR_2 PF07719.17 AAZ36017.1 - 0.023 14.8 0.1 2.8 8.3 0.0 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 AAZ36017.1 - 0.031 13.9 0.1 5.8 6.6 0.1 2.8 3 0 0 3 3 2 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_21 PF09976.9 AAZ36017.1 - 0.032 14.0 0.0 0.032 14.0 0.0 3.3 4 0 0 4 4 3 0 Tetratricopeptide repeat-like domain GAS PF13851.6 AAZ36017.1 - 0.057 12.8 4.5 0.12 11.7 4.5 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.9 AAZ36017.1 - 0.086 11.9 0.7 0.14 11.2 0.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TPR_9 PF13371.6 AAZ36017.1 - 0.13 12.5 2.4 8 6.7 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat HTH_29 PF13551.6 AAZ36017.1 - 0.13 12.3 0.0 0.38 10.8 0.0 1.9 1 0 0 1 1 1 0 Winged helix-turn helix TPR_4 PF07721.14 AAZ36017.1 - 0.15 12.8 0.0 0.15 12.8 0.0 3.3 4 0 0 4 4 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 AAZ36017.1 - 0.15 12.8 5.9 1.1 10.1 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat Spc24 PF08286.11 AAZ36017.1 - 0.17 12.1 3.7 0.37 11.0 3.7 1.5 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Cytochrom_B562 PF07361.11 AAZ36017.1 - 0.22 12.2 4.7 1 10.1 0.1 2.7 2 0 0 2 2 2 0 Cytochrome b562 DUF2771 PF10969.8 AAZ36017.1 - 0.58 10.2 2.8 6.7 6.7 0.9 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2771) DivIVA PF05103.13 AAZ36017.1 - 0.6 10.2 4.9 0.13 12.3 1.4 1.7 2 0 0 2 2 1 0 DivIVA protein ATG16 PF08614.11 AAZ36017.1 - 0.74 10.0 13.4 4 7.6 13.4 2.2 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Coatomer_E PF04733.14 AAZ36017.1 - 0.87 8.9 3.6 1.2 8.4 0.0 2.3 3 0 0 3 3 2 0 Coatomer epsilon subunit Spc7 PF08317.11 AAZ36017.1 - 2.1 7.1 9.5 0.06 12.2 3.0 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein Mod_r PF07200.13 AAZ36017.1 - 4.7 7.3 11.8 9.3 6.3 3.1 2.8 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein DUF3138 PF11336.8 AAZ36017.1 - 5.8 5.4 7.5 9.2 4.7 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF3830 PF12903.7 AAZ36018.1 - 9.6e-29 99.9 0.0 1e-28 99.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3830) Colicin_Pyocin PF01320.18 AAZ36018.1 - 0.071 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Colicin immunity protein / pyocin immunity protein DUF1993 PF09351.10 AAZ36019.1 - 1e-61 207.8 0.1 1.2e-61 207.6 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) DUF3426 PF11906.8 AAZ36020.1 - 8.1e-40 136.4 0.0 1.4e-39 135.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3426) zinc_ribbon_5 PF13719.6 AAZ36020.1 - 1.7e-09 37.3 6.1 3.7e-09 36.2 1.8 2.2 2 0 0 2 2 2 1 zinc-ribbon domain zinc_ribbon_4 PF13717.6 AAZ36020.1 - 1.7e-08 34.3 1.2 3.4e-08 33.3 1.2 1.5 1 0 0 1 1 1 1 zinc-ribbon domain GST_N_2 PF13409.6 AAZ36020.1 - 0.011 16.0 0.0 0.03 14.6 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain zf-CSL PF05207.13 AAZ36020.1 - 0.024 14.3 0.5 0.052 13.3 0.5 1.5 1 0 0 1 1 1 0 CSL zinc finger Zn_Tnp_IS1595 PF12760.7 AAZ36020.1 - 0.074 13.0 1.1 0.19 11.7 1.1 1.7 1 0 0 1 1 1 0 Transposase zinc-ribbon domain TPR_16 PF13432.6 AAZ36021.1 - 2.9e-05 24.6 12.2 0.00014 22.5 5.3 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 AAZ36021.1 - 7.7e-05 22.0 2.9 9.5e-05 21.7 2.9 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 AAZ36021.1 - 0.00055 20.4 2.6 0.00055 20.4 2.6 1.7 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_MalT PF17874.1 AAZ36021.1 - 0.0024 17.3 3.2 0.0043 16.5 3.2 1.3 1 0 0 1 1 1 1 MalT-like TPR region TPR_4 PF07721.14 AAZ36021.1 - 0.0055 17.2 5.4 0.0055 17.2 5.4 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 AAZ36021.1 - 0.026 14.9 0.6 0.13 12.6 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_21 PF09976.9 AAZ36021.1 - 0.028 14.1 4.4 0.045 13.5 4.4 1.4 1 1 0 1 1 1 0 Tetratricopeptide repeat-like domain TPR_2 PF07719.17 AAZ36021.1 - 0.037 14.1 3.7 0.25 11.6 0.3 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 AAZ36021.1 - 0.037 14.8 9.2 0.089 13.7 3.3 2.9 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 AAZ36021.1 - 0.047 13.9 0.1 3.4 8.1 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 AAZ36021.1 - 0.37 11.1 6.4 0.24 11.7 2.4 2.0 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 AAZ36021.1 - 0.89 10.3 10.9 0.64 10.8 1.9 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat XdhC_C PF13478.6 AAZ36022.1 - 2.7e-38 131.3 0.0 5.6e-38 130.3 0.0 1.5 2 0 0 2 2 2 1 XdhC Rossmann domain XdhC_CoxI PF02625.16 AAZ36022.1 - 2.5e-18 66.0 0.0 5.7e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 XdhC and CoxI family TrkA_N PF02254.18 AAZ36022.1 - 0.12 12.6 0.0 0.22 11.8 0.0 1.5 1 1 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 AAZ36022.1 - 0.16 11.6 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ROK PF00480.20 AAZ36023.1 - 4.1e-25 88.9 0.0 5.4e-22 78.6 0.0 2.2 2 0 0 2 2 2 2 ROK family MarR_2 PF12802.7 AAZ36023.1 - 0.00011 22.0 0.7 0.00029 20.6 0.5 1.8 2 0 0 2 2 2 1 MarR family HTH_24 PF13412.6 AAZ36023.1 - 0.00065 19.2 1.5 0.0016 17.9 1.0 1.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 AAZ36023.1 - 0.0092 15.9 0.3 0.055 13.4 0.5 2.0 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 AAZ36023.1 - 0.018 15.5 0.2 0.037 14.5 0.2 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_IclR PF09339.10 AAZ36023.1 - 0.08 12.8 0.4 0.25 11.1 0.4 1.8 1 0 0 1 1 1 0 IclR helix-turn-helix domain ANT PF03374.14 AAZ36023.1 - 0.21 11.9 0.0 0.42 10.9 0.0 1.4 1 0 0 1 1 1 0 Phage antirepressor protein KilAC domain HTH_AsnC-type PF13404.6 AAZ36023.1 - 1.3 9.0 4.8 7.1 6.6 1.0 2.7 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain GATase PF00117.28 AAZ36024.1 - 8e-18 64.9 0.0 1e-17 64.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 AAZ36024.1 - 1.5e-05 24.7 0.0 1.9e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 AAZ36024.1 - 0.013 15.2 0.1 0.64 9.7 0.0 2.3 2 0 0 2 2 2 0 Peptidase C26 YceI PF04264.13 AAZ36025.1 - 2e-09 38.1 0.0 2.4e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 YceI-like domain DUF4105 PF13387.6 AAZ36026.1 - 1.6e-58 197.1 0.0 3.2e-58 196.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4105) TauE PF01925.19 AAZ36027.1 - 2.1e-41 142.1 37.2 2.5e-41 141.9 37.2 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE DUF3278 PF11683.8 AAZ36027.1 - 0.065 13.3 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) Acyl_transf_1 PF00698.21 AAZ36028.1 - 3.4e-38 131.9 2.5 4e-38 131.7 2.5 1.0 1 0 0 1 1 1 1 Acyl transferase domain PseudoU_synth_2 PF00849.22 AAZ36029.1 - 3.3e-16 59.8 0.0 7.4e-16 58.6 0.0 1.6 1 1 0 1 1 1 1 RNA pseudouridylate synthase Epimerase PF01370.21 AAZ36030.1 - 7.3e-54 182.8 0.0 8.8e-54 182.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AAZ36030.1 - 2.1e-50 172.0 0.0 2.8e-50 171.6 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 AAZ36030.1 - 7.7e-19 67.8 0.0 1e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 AAZ36030.1 - 4.3e-16 58.9 0.0 5.8e-15 55.2 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 AAZ36030.1 - 1.2e-12 47.5 0.0 1.8e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 AAZ36030.1 - 1.4e-12 47.5 0.1 2.5e-12 46.7 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAZ36030.1 - 1.6e-11 44.4 0.0 2.6e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 AAZ36030.1 - 1.3e-09 38.0 0.0 4.3e-08 33.0 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 AAZ36030.1 - 1.4e-08 34.8 0.0 1.9e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 AAZ36030.1 - 1.6e-08 34.0 0.0 1.6e-07 30.7 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein adh_short_C2 PF13561.6 AAZ36030.1 - 1.4e-05 24.8 0.1 3e-05 23.7 0.1 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase TrkA_N PF02254.18 AAZ36030.1 - 0.00076 19.7 0.0 0.0013 19.0 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain DAO PF01266.24 AAZ36030.1 - 0.036 13.7 0.3 0.21 11.1 0.1 2.0 1 1 1 2 2 2 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 AAZ36030.1 - 0.074 12.6 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 AAZ36030.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain LysR_substrate PF03466.20 AAZ36031.1 - 4.8e-41 140.4 0.5 8.7e-41 139.6 0.5 1.4 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ36031.1 - 3.6e-22 78.1 1.2 3.6e-22 78.1 1.2 2.2 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family PBP_like PF12727.7 AAZ36031.1 - 0.0042 16.2 0.0 0.088 11.9 0.0 2.2 2 0 0 2 2 2 1 PBP superfamily domain HTH_30 PF13556.6 AAZ36031.1 - 0.024 14.4 0.1 0.044 13.6 0.1 1.4 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Glyco_trans_1_3 PF13528.6 AAZ36031.1 - 0.046 13.0 0.0 0.084 12.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 MarR_2 PF12802.7 AAZ36031.1 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 MarR family NdhN PF11909.8 AAZ36031.1 - 0.14 11.9 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 NADH-quinone oxidoreductase cyanobacterial subunit N Arg_repressor PF01316.21 AAZ36031.1 - 0.18 11.6 0.0 0.63 9.8 0.0 1.8 1 1 1 2 2 2 0 Arginine repressor, DNA binding domain HTH_AsnC-type PF13404.6 AAZ36031.1 - 0.57 10.1 0.0 0.57 10.1 0.0 2.2 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain DUF4136 PF13590.6 AAZ36032.1 - 2.1e-30 106.0 0.2 2.4e-30 105.8 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4136) Lysis_col PF02402.16 AAZ36032.1 - 0.076 12.7 0.2 0.13 12.0 0.2 1.3 1 0 0 1 1 1 0 Lysis protein Carboxyl_trans PF01039.22 AAZ36033.1 - 7.6e-155 516.3 0.0 9.5e-155 516.0 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 AAZ36033.1 - 6.2e-05 22.6 1.6 0.007 15.9 0.1 2.2 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) ECH_1 PF00378.20 AAZ36033.1 - 0.15 11.4 0.2 0.33 10.2 0.2 1.5 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase MerR_1 PF13411.6 AAZ36034.1 - 1e-21 76.8 0.1 1.7e-21 76.1 0.1 1.3 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR-DNA-bind PF09278.11 AAZ36034.1 - 2.7e-20 72.7 2.2 4.9e-20 71.8 2.2 1.5 1 0 0 1 1 1 1 MerR, DNA binding MerR PF00376.23 AAZ36034.1 - 2e-17 62.6 0.4 3.6e-17 61.8 0.4 1.4 1 0 0 1 1 1 1 MerR family regulatory protein Pkip-1 PF06878.11 AAZ36034.1 - 0.033 14.3 0.4 0.13 12.4 0.1 1.7 1 1 1 2 2 2 0 Pkip-1 protein CHASE3 PF05227.13 AAZ36034.1 - 0.061 13.2 0.2 0.1 12.5 0.2 1.4 1 0 0 1 1 1 0 CHASE3 domain Fzo_mitofusin PF04799.13 AAZ36034.1 - 0.086 12.4 0.3 0.12 12.0 0.3 1.1 1 0 0 1 1 1 0 fzo-like conserved region HlyD_D4 PF16572.5 AAZ36034.1 - 0.12 12.3 0.1 0.37 10.7 0.1 1.9 1 1 0 1 1 1 0 Long alpha hairpin domain of cation efflux system protein, CusB DUF1836 PF08876.11 AAZ36034.1 - 0.13 12.3 0.0 0.36 10.9 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1836) DAO PF01266.24 AAZ36035.1 - 1.7e-48 166.0 3.0 2.3e-48 165.6 1.5 1.8 2 1 1 3 3 3 1 FAD dependent oxidoreductase Methyltransf_30 PF05430.11 AAZ36035.1 - 1e-41 141.7 0.0 1.7e-41 141.0 0.0 1.3 1 0 0 1 1 1 1 S-adenosyl-L-methionine-dependent methyltransferase NAD_binding_8 PF13450.6 AAZ36035.1 - 1.9e-06 28.0 0.2 3.7e-06 27.1 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 AAZ36035.1 - 2.5e-05 23.7 0.1 5.5e-05 22.6 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 AAZ36035.1 - 0.00015 21.0 0.3 0.00021 20.5 0.3 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 AAZ36035.1 - 0.00058 19.2 0.0 0.0014 17.9 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AAZ36035.1 - 0.00069 18.8 0.6 0.0012 18.1 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 AAZ36035.1 - 0.0018 18.8 0.0 0.0065 17.0 0.0 1.9 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 AAZ36035.1 - 0.0027 17.6 0.1 0.014 15.3 0.1 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 AAZ36035.1 - 0.0086 14.8 0.1 0.014 14.1 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein DUF782 PF05614.11 AAZ36035.1 - 0.01 16.2 0.0 0.51 10.7 0.0 2.3 2 0 0 2 2 2 0 Circovirus protein of unknown function (DUF782) Shikimate_DH PF01488.20 AAZ36035.1 - 0.04 14.0 0.0 0.076 13.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.12 AAZ36035.1 - 0.054 12.5 0.9 0.1 11.6 0.3 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_oxidored PF12831.7 AAZ36035.1 - 0.12 11.7 0.5 0.19 11.0 0.5 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 AAZ36035.1 - 0.13 11.5 0.1 0.2 10.9 0.1 1.2 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 AAZ36035.1 - 0.18 11.0 0.1 0.31 10.3 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 AAZ36035.1 - 0.24 11.0 0.2 0.51 10.0 0.2 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA LysR_substrate PF03466.20 AAZ36036.1 - 9.6e-43 146.0 2.4 1.3e-42 145.5 2.4 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ36036.1 - 3.5e-20 71.7 0.4 3.5e-20 71.7 0.4 2.0 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family PBP_like PF12727.7 AAZ36036.1 - 0.14 11.3 0.0 0.41 9.7 0.0 1.7 1 1 1 2 2 2 0 PBP superfamily domain TonB_dep_Rec PF00593.24 AAZ36038.1 - 1.1e-47 164.0 39.1 1.9e-47 163.3 39.1 1.5 1 0 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AAZ36038.1 - 1e-19 71.1 0.5 1e-19 71.1 0.5 2.3 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain STN PF07660.14 AAZ36038.1 - 7.3e-10 38.5 0.1 2e-09 37.1 0.1 1.8 1 0 0 1 1 1 1 Secretin and TonB N terminus short domain OMP_b-brl_3 PF14905.6 AAZ36038.1 - 4.5e-07 29.2 11.0 3.4e-05 23.0 11.0 2.7 1 1 0 1 1 1 1 Outer membrane protein beta-barrel family Ribosomal_S30AE PF02482.19 AAZ36039.1 - 6.2e-27 94.2 2.4 7e-27 94.1 2.4 1.0 1 0 0 1 1 1 1 Sigma 54 modulation protein / S30EA ribosomal protein MOSP_N PF02707.16 AAZ36039.1 - 0.0027 17.5 0.1 0.0039 17.0 0.1 1.2 1 1 0 1 1 1 1 Major Outer Sheath Protein N-terminal region Aminotran_1_2 PF00155.21 AAZ36040.1 - 1e-58 199.2 0.0 1.2e-58 199.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 AAZ36040.1 - 0.046 12.6 0.1 1.4 7.7 0.1 2.3 1 1 0 2 2 2 0 Allinase Flg_hook PF02120.16 AAZ36041.1 - 1.4e-19 69.7 2.6 1.4e-19 69.7 2.6 2.4 2 0 0 2 2 2 1 Flagellar hook-length control protein FliK E1-E2_ATPase PF00122.20 AAZ36042.1 - 3.1e-52 176.7 5.9 7.4e-52 175.5 1.7 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 AAZ36042.1 - 4.2e-40 138.3 1.2 9.2e-40 137.2 1.2 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 AAZ36042.1 - 6.5e-17 61.7 0.0 1.4e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 AAZ36042.1 - 0.0019 18.0 3.1 0.011 15.6 1.9 2.1 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AAZ36042.1 - 0.013 15.9 0.1 0.075 13.4 0.1 2.2 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AAZ36042.1 - 0.027 14.6 0.0 0.1 12.7 0.0 2.0 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Eno-Rase_NADH_b PF12242.8 AAZ36042.1 - 0.94 9.3 3.2 8.7 6.2 0.1 2.6 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Lum_binding PF00677.17 AAZ36043.1 - 2.3e-47 158.9 0.6 1.8e-24 85.5 0.1 2.1 2 0 0 2 2 2 2 Lumazine binding domain ACR_tran PF00873.19 AAZ36044.1 - 2.3e-296 985.7 20.3 2.6e-296 985.5 20.3 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AAZ36044.1 - 3.4e-18 65.7 26.7 9.6e-15 54.3 12.5 2.5 2 0 0 2 2 2 2 MMPL family SecD_SecF PF02355.16 AAZ36044.1 - 5.8e-09 35.6 34.3 6.9e-06 25.6 19.4 3.0 2 1 1 3 3 3 3 Protein export membrane protein LysE PF01810.18 AAZ36045.1 - 1.9e-23 82.9 16.9 2.2e-23 82.7 16.9 1.0 1 0 0 1 1 1 1 LysE type translocator DUF3397 PF11877.8 AAZ36045.1 - 0.011 15.9 1.7 0.011 15.9 1.7 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3397) Herpes_UL49_5 PF05702.11 AAZ36045.1 - 0.22 11.6 4.8 0.35 11.0 1.4 2.7 1 1 2 3 3 3 0 Herpesvirus UL49.5 envelope/tegument protein DUF962 PF06127.11 AAZ36045.1 - 0.51 10.5 3.5 0.26 11.4 0.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF962) Alginate_lyase2 PF08787.11 AAZ36046.1 - 3.5e-58 197.2 3.2 4e-58 197.1 3.2 1.0 1 0 0 1 1 1 1 Alginate lyase SNase PF00565.17 AAZ36047.1 - 5.9e-16 58.9 0.0 9.8e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Tyr_Deacylase PF02580.16 AAZ36048.1 - 2.2e-48 164.4 0.0 2.5e-48 164.3 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase CesT PF05932.13 AAZ36048.1 - 0.12 12.5 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Tir chaperone protein (CesT) family K_trans PF02705.16 AAZ36049.1 - 2.5e-206 686.3 21.9 3e-206 686.1 21.9 1.0 1 0 0 1 1 1 1 K+ potassium transporter HlyD_D23 PF16576.5 AAZ36051.1 - 1.4e-15 57.1 3.0 4e-13 49.1 1.1 2.6 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 AAZ36051.1 - 3.7e-12 45.9 2.3 2e-09 37.1 0.2 3.2 3 0 0 3 3 3 2 Biotin-lipoyl like HlyD_3 PF13437.6 AAZ36051.1 - 2e-10 41.3 1.1 3.6e-05 24.4 0.1 3.0 2 1 0 2 2 2 2 HlyD family secretion protein HlyD PF00529.20 AAZ36051.1 - 2e-05 24.4 15.9 4.2e-05 23.4 15.9 1.9 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS CALCOCO1 PF07888.11 AAZ36051.1 - 0.068 12.0 0.2 0.11 11.4 0.2 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Biotin_lipoyl PF00364.22 AAZ36051.1 - 0.076 12.9 0.6 22 5.0 0.0 3.7 4 0 0 4 4 4 0 Biotin-requiring enzyme MIX PF18529.1 AAZ36051.1 - 0.15 11.7 0.0 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial membrane-anchored proteins ABC_tran PF00005.27 AAZ36052.1 - 2.8e-29 102.4 0.0 3.5e-29 102.1 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAZ36052.1 - 9.2e-11 42.1 0.0 6.6e-05 22.9 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAZ36052.1 - 1.4e-05 24.6 0.0 0.029 13.8 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AAZ36052.1 - 0.00032 21.1 0.1 0.00047 20.6 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.6 AAZ36052.1 - 0.0071 16.1 0.2 0.051 13.3 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 AAZ36052.1 - 0.01 16.3 0.0 0.016 15.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 AAZ36052.1 - 0.013 15.7 0.0 0.18 12.0 0.0 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 AAZ36052.1 - 0.044 13.5 0.0 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 AAZ36052.1 - 0.066 13.5 0.0 1.9 8.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain BCA_ABC_TP_C PF12399.8 AAZ36052.1 - 0.068 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Branched-chain amino acid ATP-binding cassette transporter tRNA-synt_2 PF00152.20 AAZ36053.1 - 6.1e-111 370.5 0.0 7.4e-111 370.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) GAD PF02938.14 AAZ36053.1 - 1.2e-30 105.5 0.0 2.3e-30 104.7 0.0 1.5 1 0 0 1 1 1 1 GAD domain tRNA_anti-codon PF01336.25 AAZ36053.1 - 9.1e-17 60.8 0.1 3.4e-16 59.0 0.0 1.9 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 AAZ36053.1 - 0.00024 20.7 1.0 0.079 12.4 0.2 2.6 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) ADH_N PF08240.12 AAZ36054.1 - 5.1e-25 87.5 3.2 1.2e-24 86.3 3.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AAZ36054.1 - 2.8e-19 69.4 0.1 5.6e-19 68.4 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 AAZ36054.1 - 1.9e-05 24.1 0.0 3.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 AAZ36054.1 - 2.5e-05 23.7 0.1 4.2e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 AAZ36054.1 - 0.0035 17.5 0.1 0.0063 16.7 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ADH_zinc_N_2 PF13602.6 AAZ36054.1 - 0.0071 17.4 0.0 0.011 16.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ApbA PF02558.16 AAZ36054.1 - 0.0074 15.9 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 AAZ36054.1 - 0.014 15.2 0.1 0.024 14.6 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 AAZ36054.1 - 0.026 15.2 0.0 0.058 14.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Shikimate_DH PF01488.20 AAZ36054.1 - 0.062 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Amidase PF01425.21 AAZ36055.1 - 3.5e-161 537.2 0.0 3.9e-161 537.0 0.0 1.0 1 0 0 1 1 1 1 Amidase GSDH PF07995.11 AAZ36056.1 - 1e-138 462.2 0.1 1.2e-138 462.0 0.1 1.0 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase DUF1653 PF07866.11 AAZ36057.1 - 6.8e-30 103.2 0.4 8.6e-30 102.8 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1653) Fimbrial PF00419.20 AAZ36058.1 - 6.3e-08 33.0 0.4 8.6e-08 32.6 0.4 1.2 1 0 0 1 1 1 1 Fimbrial protein COQ7 PF03232.13 AAZ36059.1 - 1.1e-37 129.4 0.3 1.3e-37 129.2 0.3 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 AAZ36059.1 - 4.2e-08 33.7 0.0 7e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Rubrerythrin Ferritin PF00210.24 AAZ36059.1 - 0.00012 22.0 0.1 0.00021 21.2 0.1 1.3 1 0 0 1 1 1 1 Ferritin-like domain DUF455 PF04305.14 AAZ36059.1 - 0.31 10.5 2.7 2.1 7.8 2.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF455) Sigma54_activat PF00158.26 AAZ36060.1 - 4.7e-53 179.3 0.0 6.2e-53 179.0 0.0 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AAZ36060.1 - 8.1e-23 81.1 0.0 1.6e-22 80.1 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 AAZ36060.1 - 0.00072 19.6 0.0 0.006 16.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AAZ36060.1 - 0.0016 18.8 1.3 0.0032 17.9 0.1 2.2 2 1 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 AAZ36060.1 - 0.0043 16.5 0.0 0.31 10.4 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 AAZ36060.1 - 0.11 12.1 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 AAZ36060.1 - 0.11 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 KaiC Flavodoxin_2 PF02525.17 AAZ36061.1 - 1e-33 116.7 0.0 1.3e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 AAZ36061.1 - 2e-14 53.6 0.0 2.4e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Dyp_perox PF04261.12 AAZ36062.1 - 3.8e-102 341.6 0.0 4.5e-102 341.4 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family PsbQ PF05757.11 AAZ36062.1 - 0.1 12.4 0.2 0.19 11.5 0.2 1.4 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) Glyco_hydro_68 PF02435.16 AAZ36063.1 - 4.7e-172 572.6 0.0 5.4e-172 572.4 0.0 1.0 1 0 0 1 1 1 1 Levansucrase/Invertase Glyco_hydro_43 PF04616.14 AAZ36063.1 - 0.00077 18.9 0.1 0.009 15.4 0.1 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 LysR_substrate PF03466.20 AAZ36064.1 - 2.2e-45 154.6 1.8 4.8e-45 153.5 0.5 1.9 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ36064.1 - 7.4e-16 57.9 1.8 1.4e-15 57.0 1.8 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AAZ36064.1 - 0.026 14.3 0.3 0.084 12.7 0.3 1.9 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain MCPsignal PF00015.21 AAZ36065.1 - 2.2e-31 109.0 11.3 2.2e-31 109.0 11.3 2.5 2 1 1 3 3 3 1 Methyl-accepting chemotaxis protein (MCP) signalling domain FIST PF08495.10 AAZ36065.1 - 1.3e-25 90.3 0.0 3.4e-20 72.7 0.0 2.5 2 0 0 2 2 2 2 FIST N domain FIST_C PF10442.9 AAZ36065.1 - 1.9e-13 50.5 2.3 2.2e-13 50.3 0.1 2.2 2 1 0 2 2 2 1 FIST C domain DUF948 PF06103.11 AAZ36065.1 - 0.0003 21.0 6.3 0.013 15.7 0.5 2.8 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 AAZ36065.1 - 0.0075 16.3 9.6 0.18 11.8 2.0 2.5 2 0 0 2 2 2 2 Laminin Domain II DUF812 PF05667.11 AAZ36065.1 - 0.0085 15.0 5.2 0.017 14.1 5.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF812) DUF16 PF01519.16 AAZ36065.1 - 0.017 15.6 7.6 0.8 10.2 2.2 2.8 2 1 0 2 2 2 0 Protein of unknown function DUF16 DUF5082 PF16888.5 AAZ36065.1 - 0.037 14.3 3.4 2.3 8.5 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Collagen_mid PF15984.5 AAZ36065.1 - 0.064 13.0 2.7 0.41 10.4 1.6 2.1 1 1 1 2 2 2 0 Bacterial collagen, middle region Ribosomal_L5 PF00281.19 AAZ36065.1 - 0.068 13.5 0.6 3.4 8.1 0.0 2.6 2 0 0 2 2 2 0 Ribosomal protein L5 SlyX PF04102.12 AAZ36065.1 - 0.3 11.7 11.7 0.76 10.4 0.2 4.5 4 1 1 5 5 4 0 SlyX DUF1664 PF07889.12 AAZ36065.1 - 0.3 11.1 8.3 7.6 6.6 3.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) COG5 PF10392.9 AAZ36065.1 - 0.35 11.0 6.8 0.54 10.4 0.5 3.0 3 0 0 3 3 3 0 Golgi transport complex subunit 5 TMF_DNA_bd PF12329.8 AAZ36065.1 - 0.45 10.5 4.1 16 5.5 0.1 2.9 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding COG2 PF06148.11 AAZ36065.1 - 0.88 9.7 3.5 23 5.0 0.3 2.9 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.11 AAZ36065.1 - 1 8.2 7.0 3 6.7 1.8 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein T7SS_ESX_EspC PF10824.8 AAZ36065.1 - 4.7 7.8 7.6 8.4 6.9 0.7 3.4 1 1 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm HSP33 PF01430.19 AAZ36066.1 - 4.9e-77 259.0 0.0 5.5e-77 258.8 0.0 1.0 1 0 0 1 1 1 1 Hsp33 protein SBP_bac_3 PF00497.20 AAZ36067.1 - 3.3e-68 229.5 0.3 3.8e-68 229.3 0.3 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 AAZ36067.1 - 3.4e-12 46.6 0.0 7.7e-12 45.4 0.0 1.6 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site Methyltransf_11 PF08241.12 AAZ36068.1 - 4.7e-15 56.0 0.0 7.8e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAZ36068.1 - 1.6e-14 54.1 0.0 2.3e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAZ36068.1 - 2.3e-14 53.9 0.0 4.9e-14 52.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAZ36068.1 - 8.3e-13 48.4 0.0 1.1e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAZ36068.1 - 1.7e-11 44.7 0.0 2.7e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AAZ36068.1 - 0.00077 19.0 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 AAZ36068.1 - 0.0014 18.1 0.0 0.002 17.6 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB RrnaAD PF00398.20 AAZ36068.1 - 0.0035 16.4 0.0 0.0051 15.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DREV PF05219.12 AAZ36068.1 - 0.037 13.1 0.0 0.06 12.4 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase HAD PF12710.7 AAZ36069.1 - 7.5e-26 91.7 0.1 1.3e-25 90.9 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase ACT_6 PF13740.6 AAZ36069.1 - 8.9e-26 89.7 2.5 2.1e-25 88.5 0.3 2.5 3 0 0 3 3 3 1 ACT domain Hydrolase PF00702.26 AAZ36069.1 - 2.5e-19 70.4 1.0 5.9e-19 69.2 0.7 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AAZ36069.1 - 6.7e-13 49.0 0.0 2.3e-11 44.0 0.0 2.7 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase ACT PF01842.25 AAZ36069.1 - 2.1e-07 30.6 1.7 6e-07 29.1 0.8 2.2 2 0 0 2 2 2 1 ACT domain ACT_4 PF13291.6 AAZ36069.1 - 0.00017 22.1 0.1 0.00042 20.8 0.1 1.6 1 0 0 1 1 1 1 ACT domain HAD_2 PF13419.6 AAZ36069.1 - 0.00046 20.3 0.1 0.004 17.3 0.1 2.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 AAZ36069.1 - 0.0026 17.2 0.0 1 8.7 0.0 2.2 2 0 0 2 2 2 2 Putative Phosphatase ACT_7 PF13840.6 AAZ36069.1 - 0.056 13.2 0.5 0.17 11.7 0.1 2.0 2 0 0 2 2 2 0 ACT domain Acid_PPase PF12689.7 AAZ36069.1 - 0.12 12.2 0.0 0.39 10.6 0.0 1.8 1 1 0 1 1 1 0 Acid Phosphatase DUF1525 PF07511.11 AAZ36071.1 - 3.7e-35 120.5 2.9 4.5e-35 120.2 2.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1525) YkuD PF03734.14 AAZ36072.1 - 5.6e-18 65.8 0.0 7.4e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain YkuD_2 PF13645.6 AAZ36072.1 - 0.012 15.0 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 0 L,D-transpeptidase catalytic domain DUF1348 PF07080.11 AAZ36073.1 - 1.4e-65 219.0 7.0 1.6e-65 218.8 7.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 AAZ36073.1 - 5.3e-06 27.0 2.0 6.6e-06 26.7 2.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 AAZ36073.1 - 0.0031 17.9 0.3 0.0042 17.5 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Hfq PF17209.3 AAZ36074.1 - 3.5e-30 103.4 0.4 4e-30 103.2 0.4 1.0 1 0 0 1 1 1 1 Hfq protein LSM PF01423.22 AAZ36074.1 - 0.0016 18.1 0.1 0.0019 17.8 0.1 1.3 1 0 0 1 1 1 1 LSM domain Usp PF00582.26 AAZ36075.1 - 1.2e-22 81.0 0.1 1.6e-22 80.5 0.1 1.2 1 0 0 1 1 1 1 Universal stress protein family DUF4096 PF13340.6 AAZ36076.1 - 5.8e-25 87.3 0.4 1.5e-24 86.0 0.4 1.8 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1 PF01609.21 AAZ36076.1 - 3.2e-14 53.1 0.0 5.7e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AAZ36076.1 - 7.2e-10 39.1 0.2 2.1e-09 37.6 0.2 1.9 1 0 0 1 1 1 1 Transposase DDE domain HTH_Tnp_Tc3_2 PF01498.18 AAZ36076.1 - 0.061 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Transposase SBP_bac_3 PF00497.20 AAZ36077.1 - 5.1e-36 124.2 0.0 6e-36 124.0 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 AAZ36077.1 - 0.011 15.9 0.0 1.2 9.3 0.0 3.0 2 1 0 2 2 2 0 Ligated ion channel L-glutamate- and glycine-binding site IF3_C PF00707.22 AAZ36078.1 - 8e-37 125.1 0.2 1.3e-36 124.5 0.2 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.16 AAZ36078.1 - 5.3e-29 100.3 0.1 1.1e-28 99.2 0.1 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain TMEMspv1-c74-12 PF11044.8 AAZ36078.1 - 0.024 14.6 4.8 0.043 13.8 4.8 1.4 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein PAS_7 PF12860.7 AAZ36079.1 - 1.8e-45 153.8 0.0 1.2e-44 151.2 0.0 2.4 2 0 0 2 2 2 1 PAS fold HATPase_c PF02518.26 AAZ36079.1 - 5.2e-16 59.1 0.0 1e-15 58.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAZ36079.1 - 8.3e-12 45.0 1.3 8.3e-12 45.0 1.3 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 AAZ36079.1 - 1.1e-09 38.5 0.0 2.3e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain PAS_8 PF13188.7 AAZ36079.1 - 1.1e-05 25.3 0.8 5.6e-05 23.1 0.0 2.7 3 0 0 3 3 3 1 PAS domain PAS PF00989.25 AAZ36079.1 - 0.0042 17.1 0.0 0.012 15.6 0.0 1.8 1 1 0 1 1 1 1 PAS fold HATPase_c_2 PF13581.6 AAZ36079.1 - 0.09 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain TetR_N PF00440.23 AAZ36080.1 - 1.6e-11 43.8 0.0 3.5e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_15 PF17918.1 AAZ36080.1 - 0.00033 21.4 2.4 0.00033 21.4 2.4 2.0 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_22 PF17928.1 AAZ36080.1 - 0.0037 17.6 1.2 0.0074 16.6 1.2 1.6 1 1 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain Tail_P2_I PF09684.10 AAZ36080.1 - 0.044 13.7 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 Phage tail protein (Tail_P2_I) Sugar_tr PF00083.24 AAZ36082.1 - 9.6e-30 103.8 34.2 4e-24 85.3 10.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 AAZ36082.1 - 4.8e-29 101.4 46.7 5.4e-29 101.2 46.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 AAZ36082.1 - 0.00061 18.8 10.6 0.0082 15.0 2.2 2.8 2 1 0 2 2 2 2 MFS_1 like family BPD_transp_1 PF00528.22 AAZ36083.1 - 1e-26 93.8 5.0 1e-26 93.8 5.0 1.7 1 1 1 2 2 2 2 Binding-protein-dependent transport system inner membrane component AsmA PF05170.14 AAZ36084.1 - 1e-140 470.5 0.0 1.2e-140 470.2 0.0 1.1 1 0 0 1 1 1 1 AsmA family AsmA_2 PF13502.6 AAZ36084.1 - 5.6e-18 65.3 1.9 5.6e-18 65.3 1.9 2.7 3 0 0 3 3 3 1 AsmA-like C-terminal region DUF748 PF05359.11 AAZ36084.1 - 0.00053 20.2 3.1 2 8.6 0.1 3.7 2 2 1 3 3 3 2 Domain of Unknown Function (DUF748) DUF2484 PF10658.9 AAZ36084.1 - 0.11 12.8 2.2 4.4 7.7 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2484) vWA-TerF-like PF10138.9 AAZ36085.1 - 7.5e-81 271.0 0.0 1.4e-80 270.2 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus TerD PF02342.18 AAZ36085.1 - 3.4e-24 85.4 0.0 1.3e-22 80.2 0.0 2.2 2 0 0 2 2 2 1 TerD domain Copine PF07002.16 AAZ36085.1 - 3.3e-06 26.7 0.0 0.015 14.8 0.0 2.6 2 0 0 2 2 2 2 Copine PilZ PF07238.14 AAZ36086.1 - 6.7e-16 58.5 0.0 1.7e-15 57.2 0.0 1.6 2 0 0 2 2 2 1 PilZ domain BicD PF09730.9 AAZ36086.1 - 0.029 12.8 0.2 0.037 12.5 0.2 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D Cid2 PF09774.9 AAZ36086.1 - 0.069 13.6 0.3 0.12 12.7 0.1 1.4 2 0 0 2 2 2 0 Caffeine-induced death protein 2 Glyco_hydro_19 PF00182.19 AAZ36087.1 - 2.8e-10 40.5 0.0 8.9e-10 38.8 0.0 1.7 1 1 0 1 1 1 1 Chitinase class I AFG1_ATPase PF03969.16 AAZ36088.1 - 1.1e-96 323.9 0.6 7.3e-79 265.3 0.1 2.9 2 1 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 AAZ36088.1 - 0.0012 19.3 0.0 0.0033 17.8 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 AAZ36088.1 - 0.0041 17.4 0.0 0.008 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 AAZ36088.1 - 0.043 13.8 0.0 0.071 13.1 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TsaE PF02367.17 AAZ36088.1 - 0.058 13.4 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 AAZ36088.1 - 0.079 13.4 0.0 0.22 12.0 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 AAZ36088.1 - 0.094 12.1 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein IstB_IS21 PF01695.17 AAZ36088.1 - 0.13 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein FecCD PF01032.18 AAZ36089.1 - 3.9e-87 292.2 39.4 4.8e-87 291.9 39.4 1.0 1 0 0 1 1 1 1 FecCD transport family DUF3397 PF11877.8 AAZ36089.1 - 0.059 13.6 0.3 0.059 13.6 0.3 2.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3397) BPD_transp_1 PF00528.22 AAZ36090.1 - 8.2e-09 35.5 18.0 8.2e-09 35.5 18.0 1.9 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component Ribosomal_L28 PF00830.19 AAZ36091.1 - 7.3e-28 96.6 1.5 8.5e-28 96.3 1.5 1.1 1 0 0 1 1 1 1 Ribosomal L28 family Asparaginase_II PF06089.12 AAZ36091.1 - 0.13 11.2 0.0 0.13 11.2 0.0 1.0 1 0 0 1 1 1 0 L-asparaginase II DUF4395 PF14340.6 AAZ36092.1 - 0.17 12.2 11.4 0.24 11.8 11.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4395) ABC_tran PF00005.27 AAZ36093.1 - 8.6e-36 123.5 0.1 1.6e-35 122.6 0.1 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 AAZ36093.1 - 9.6e-11 41.8 9.6 1.7e-10 41.1 9.6 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 AAZ36093.1 - 2e-07 30.7 0.0 1.1e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 AAZ36093.1 - 0.00078 19.4 0.1 0.0017 18.3 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 AAZ36093.1 - 0.0011 19.4 0.2 0.0035 17.8 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.15 AAZ36093.1 - 0.0017 18.3 0.2 1.4 8.8 0.0 2.3 2 0 0 2 2 2 2 NTPase AAA_29 PF13555.6 AAZ36093.1 - 0.0024 17.6 0.1 0.0057 16.4 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 AAZ36093.1 - 0.0026 17.8 0.1 0.011 15.8 0.1 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 AAZ36093.1 - 0.0035 17.6 1.0 0.031 14.6 0.2 2.6 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 AAZ36093.1 - 0.012 15.3 0.0 0.19 11.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 AAZ36093.1 - 0.017 15.6 1.8 0.2 12.1 0.3 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 AAZ36093.1 - 0.018 14.8 0.1 0.052 13.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain DUF3112 PF11309.8 AAZ36093.1 - 0.037 13.5 0.6 0.12 11.8 0.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3112) AAA_21 PF13304.6 AAZ36093.1 - 0.047 13.5 0.1 0.19 11.5 0.0 1.7 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 AAZ36093.1 - 0.049 14.2 0.0 0.099 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Iron_permease PF04120.12 AAZ36093.1 - 0.055 13.2 0.2 0.14 11.9 0.2 1.6 1 0 0 1 1 1 0 Low affinity iron permease AAA_5 PF07728.14 AAZ36093.1 - 0.061 13.3 2.0 0.28 11.2 0.0 2.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Ndc1_Nup PF09531.10 AAZ36093.1 - 0.081 11.6 0.4 0.17 10.5 0.4 1.5 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup AAA_33 PF13671.6 AAZ36093.1 - 0.097 12.8 0.1 0.32 11.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.17 AAZ36093.1 - 0.1 12.6 0.2 0.51 10.4 0.2 2.0 1 1 0 1 1 1 0 Helicase HerA, central domain CTP_transf_like PF01467.26 AAZ36094.1 - 6.3e-24 84.8 0.0 7.6e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like Citrate_ly_lig PF08218.11 AAZ36094.1 - 1.8e-06 27.8 0.0 2.7e-06 27.2 0.0 1.3 1 1 0 1 1 1 1 Citrate lyase ligase C-terminal domain DAO PF01266.24 AAZ36095.1 - 5.2e-47 161.1 5.9 6.1e-47 160.9 5.9 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AAZ36095.1 - 3.4e-06 26.4 2.2 6.4e-06 25.5 2.2 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 AAZ36095.1 - 9.1e-06 25.1 1.4 0.039 13.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AAZ36095.1 - 3.1e-05 23.4 1.4 5.4e-05 22.6 1.4 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 AAZ36095.1 - 0.00063 19.0 0.7 0.0022 17.3 0.6 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 AAZ36095.1 - 0.00079 18.7 0.1 0.001 18.4 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AAZ36095.1 - 0.0031 16.9 0.6 0.004 16.5 0.6 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 AAZ36095.1 - 0.0038 16.0 1.2 0.044 12.5 0.9 2.0 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 AAZ36095.1 - 0.0046 17.2 4.2 0.0054 16.9 1.9 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 AAZ36095.1 - 0.0049 16.2 0.4 0.54 9.5 0.1 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 AAZ36095.1 - 0.006 16.6 1.1 0.068 13.2 0.6 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 AAZ36095.1 - 0.043 14.4 0.7 0.096 13.3 0.7 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AAZ36095.1 - 0.068 12.2 1.4 0.14 11.2 0.6 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 AAZ36095.1 - 0.11 11.5 0.6 0.16 10.9 0.6 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Abhydrolase_3 PF07859.13 AAZ36096.1 - 7e-61 205.7 0.0 9.6e-61 205.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 AAZ36096.1 - 1.2e-16 60.7 0.0 4e-16 59.0 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 AAZ36096.1 - 6.3e-07 30.2 6.2 1.4e-06 29.1 6.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 AAZ36096.1 - 2e-06 27.5 0.0 6.1e-05 22.6 0.0 2.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 AAZ36096.1 - 3e-05 23.4 0.1 0.00012 21.4 0.1 2.0 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Say1_Mug180 PF10340.9 AAZ36096.1 - 7e-05 21.8 0.0 9.7e-05 21.4 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase DLH PF01738.18 AAZ36096.1 - 0.0037 16.9 0.0 0.14 11.7 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Chlorophyllase2 PF12740.7 AAZ36096.1 - 0.0039 16.1 0.0 0.006 15.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Thioesterase PF00975.20 AAZ36096.1 - 0.065 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Lipase_3 PF01764.25 AAZ36096.1 - 0.14 12.0 0.4 0.27 11.1 0.4 1.4 1 0 0 1 1 1 0 Lipase (class 3) UIM PF02809.20 AAZ36096.1 - 1.7 8.8 0.0 1.7 8.8 0.0 2.8 3 0 0 3 3 3 0 Ubiquitin interaction motif adh_short_C2 PF13561.6 AAZ36097.1 - 1.1e-65 221.4 5.1 1.3e-65 221.2 5.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAZ36097.1 - 2.6e-51 173.9 2.8 3.2e-51 173.6 2.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAZ36097.1 - 4.5e-08 33.2 0.9 7.1e-08 32.6 0.9 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 AAZ36097.1 - 0.00014 22.2 0.1 0.00025 21.3 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain THF_DHG_CYH_C PF02882.19 AAZ36097.1 - 0.00024 20.4 0.9 0.00065 19.1 0.1 1.9 1 1 1 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 AAZ36097.1 - 0.019 14.4 0.1 0.26 10.7 0.1 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family T2SSL PF05134.13 AAZ36098.1 - 7e-08 32.1 1.7 7.2e-08 32.1 0.3 1.7 2 0 0 2 2 2 1 Type II secretion system (T2SS), protein L PilM_2 PF11104.8 AAZ36098.1 - 0.019 14.0 0.0 0.029 13.4 0.0 1.1 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; PilN PF05137.13 AAZ36098.1 - 0.11 12.6 0.1 0.36 11.0 0.0 1.8 2 0 0 2 2 2 0 Fimbrial assembly protein (PilN) GspL_C PF12693.7 AAZ36099.1 - 1.7e-15 57.2 4.3 2.9e-15 56.5 4.3 1.3 1 0 0 1 1 1 1 GspL periplasmic domain Cupin_6 PF12852.7 AAZ36099.1 - 0.00095 18.9 1.0 0.00095 18.9 1.0 2.0 2 1 0 2 2 2 1 Cupin T2SSL PF05134.13 AAZ36099.1 - 0.0066 15.8 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein L Amidohydro_1 PF01979.20 AAZ36100.1 - 9.2e-12 44.9 0.0 2.3e-11 43.6 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AAZ36100.1 - 1.7e-11 44.3 1.3 1.1e-08 35.0 0.0 2.8 3 0 0 3 3 3 2 Amidohydrolase family DHOase PF12890.7 AAZ36100.1 - 0.0062 16.5 0.0 0.063 13.2 0.0 2.2 1 1 0 1 1 1 1 Dihydro-orotase-like AAA_lid_5 PF17865.1 AAZ36100.1 - 0.18 11.9 0.0 0.44 10.7 0.0 1.6 2 0 0 2 2 2 0 Midasin AAA lid domain MCPsignal PF00015.21 AAZ36101.1 - 2.3e-39 135.0 29.2 2.3e-39 135.0 29.2 2.8 1 1 1 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AAZ36101.1 - 8.1e-07 29.3 0.2 8.1e-07 29.3 0.2 5.0 5 0 0 5 5 5 1 HAMP domain DUF948 PF06103.11 AAZ36101.1 - 0.051 13.8 22.7 1.3 9.4 0.5 6.3 4 2 1 5 5 5 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 AAZ36101.1 - 0.062 13.3 0.0 0.062 13.3 0.0 4.3 4 1 1 5 5 5 0 Protein of unknown function (DUF1664) COMPASS-Shg1 PF05205.12 AAZ36101.1 - 0.15 12.8 2.9 0.65 10.7 2.4 2.4 2 0 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 FliD_N PF02465.18 AAZ36101.1 - 2.7 8.7 20.1 0.65 10.7 2.8 3.9 4 0 0 4 4 4 0 Flagellar hook-associated protein 2 N-terminus DUF503 PF04456.12 AAZ36101.1 - 3.3 7.6 7.7 1.1 9.1 2.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF503) Iso_dh PF00180.20 AAZ36102.1 - 1.4e-89 300.7 0.0 1.6e-89 300.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DAO PF01266.24 AAZ36103.1 - 1.1e-62 212.7 0.1 1.2e-62 212.5 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AAZ36103.1 - 1.4e-06 28.5 0.1 2.8e-06 27.5 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AAZ36103.1 - 2.4e-06 27.0 0.0 0.0021 17.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAZ36103.1 - 4.8e-06 26.0 0.0 0.044 13.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AAZ36103.1 - 2e-05 24.0 0.2 3.6e-05 23.2 0.0 1.4 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 AAZ36103.1 - 5.1e-05 22.2 0.0 0.22 10.2 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 AAZ36103.1 - 0.00019 21.9 0.0 0.00062 20.3 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AAZ36103.1 - 0.00062 19.0 0.1 0.0034 16.5 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.14 AAZ36103.1 - 0.0042 16.0 0.0 0.0071 15.3 0.0 1.3 1 0 0 1 1 1 1 Tryptophan halogenase GIDA PF01134.22 AAZ36103.1 - 0.011 14.9 0.0 0.093 11.8 0.0 2.3 3 0 0 3 3 3 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 AAZ36103.1 - 0.023 14.6 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 AAZ36103.1 - 0.03 13.7 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Amino_oxidase PF01593.24 AAZ36103.1 - 0.038 13.3 0.0 0.074 12.3 0.0 1.4 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase ApbA PF02558.16 AAZ36103.1 - 0.054 13.2 0.1 0.093 12.4 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.6 AAZ36103.1 - 0.32 11.0 1.1 25 4.8 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding MurJ PF03023.14 AAZ36104.1 - 2.8e-154 514.1 29.4 3.6e-154 513.7 29.4 1.0 1 0 0 1 1 1 1 Lipid II flippase MurJ Polysacc_synt_C PF14667.6 AAZ36104.1 - 1.4e-12 47.9 17.6 1.4e-12 47.9 17.6 3.8 3 2 0 3 3 3 2 Polysaccharide biosynthesis C-terminal domain MatE PF01554.18 AAZ36104.1 - 0.027 14.1 31.0 0.018 14.7 3.3 4.1 2 2 1 4 4 4 0 MatE HATPase_c PF02518.26 AAZ36105.1 - 1.3e-20 73.9 0.0 2.7e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAZ36105.1 - 1.4e-11 44.2 2.9 2.4e-10 40.3 0.3 3.3 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 AAZ36105.1 - 2.4e-09 37.2 0.1 8e-09 35.5 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 AAZ36105.1 - 2.3e-08 34.3 0.0 5.4e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 PAS fold HAMP PF00672.25 AAZ36105.1 - 3.1e-08 33.8 0.3 3e-07 30.7 0.3 2.6 2 0 0 2 2 2 1 HAMP domain HATPase_c_3 PF13589.6 AAZ36105.1 - 0.00036 20.4 0.0 0.0008 19.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.7 AAZ36105.1 - 0.0005 20.0 0.0 0.0014 18.6 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 AAZ36105.1 - 0.0033 17.7 0.0 0.0076 16.5 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_10 PF13596.6 AAZ36105.1 - 0.014 16.0 0.0 0.04 14.5 0.0 1.9 1 0 0 1 1 1 0 PAS domain PAS_7 PF12860.7 AAZ36105.1 - 0.036 14.2 0.2 2.6 8.2 0.1 3.3 2 1 0 2 2 2 0 PAS fold CHASE8 PF17152.4 AAZ36105.1 - 0.061 13.6 0.0 0.18 12.0 0.0 1.8 1 0 0 1 1 1 0 Periplasmic sensor domain Nup54 PF13874.6 AAZ36105.1 - 0.12 12.5 2.3 0.3 11.2 1.8 2.0 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 APG6_N PF17675.1 AAZ36105.1 - 0.51 10.9 6.7 1.2 9.6 6.7 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region Peptidase_M42 PF05343.14 AAZ36106.1 - 3.5e-71 239.6 0.0 4.1e-71 239.4 0.0 1.0 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.28 AAZ36106.1 - 3.4e-07 30.2 0.0 7e-07 29.2 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 FAD_binding_5 PF00941.21 AAZ36108.1 - 3.3e-50 170.2 0.0 4.8e-50 169.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 AAZ36108.1 - 2.5e-21 75.8 0.4 4.3e-21 75.0 0.4 1.4 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain DUF1090 PF06476.12 AAZ36109.1 - 3.3e-32 110.9 16.0 4.6e-32 110.4 16.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1090) EMC3_TMCO1 PF01956.16 AAZ36109.1 - 0.0065 16.2 8.6 0.47 10.2 0.1 2.0 1 1 1 2 2 2 2 Integral membrane protein EMC3/TMCO1-like TarH PF02203.15 AAZ36109.1 - 0.056 13.4 3.6 0.1 12.5 3.6 1.4 1 0 0 1 1 1 0 Tar ligand binding domain homologue Selenoprotein_S PF06936.11 AAZ36109.1 - 0.071 12.9 5.4 0.034 13.9 3.0 1.6 1 1 0 1 1 1 0 Selenoprotein S (SelS) Fusion_gly PF00523.18 AAZ36109.1 - 0.079 11.2 2.5 0.065 11.5 1.5 1.4 1 1 0 1 1 1 0 Fusion glycoprotein F0 Phage_HK97_TLTM PF06120.11 AAZ36109.1 - 0.086 12.0 8.9 0.11 11.7 8.9 1.1 1 0 0 1 1 1 0 Tail length tape measure protein DUF999 PF06198.11 AAZ36109.1 - 0.21 11.6 1.7 0.3 11.1 0.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF999) Atg14 PF10186.9 AAZ36109.1 - 0.53 9.3 12.4 0.7 8.9 12.4 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 AAZ36109.1 - 0.62 10.1 7.9 0.77 9.8 7.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 AAZ36109.1 - 0.64 9.3 11.6 0.85 8.9 11.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) O-antigen_lig PF13425.6 AAZ36109.1 - 0.74 8.5 1.2 0.81 8.4 1.2 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein LMBR1 PF04791.16 AAZ36109.1 - 1.2 8.0 5.4 1.2 7.9 5.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein HSP70 PF00012.20 AAZ36109.1 - 1.5 6.9 10.7 1.7 6.7 10.7 1.0 1 0 0 1 1 1 0 Hsp70 protein Uds1 PF15456.6 AAZ36109.1 - 1.7 8.8 11.6 1.3 9.2 9.5 1.7 1 1 0 1 1 1 0 Up-regulated During Septation ABC_tran_CTD PF16326.5 AAZ36109.1 - 3.6 7.9 11.7 5.1 7.4 1.6 2.8 1 1 2 3 3 3 0 ABC transporter C-terminal domain DUF2203 PF09969.9 AAZ36109.1 - 3.9 8.2 10.8 1.6 9.4 4.8 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF1664 PF07889.12 AAZ36109.1 - 7.6 6.6 8.0 4.9 7.2 5.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) XhlA PF10779.9 AAZ36109.1 - 7.9 6.8 8.7 1.9 8.7 2.9 2.2 2 1 0 2 2 2 0 Haemolysin XhlA Phage_tail_APC PF16778.5 AAZ36110.1 - 1.1e-08 34.8 0.9 1.8e-08 34.1 0.9 1.3 1 0 0 1 1 1 1 Phage tail assembly chaperone protein Caudo_TAP PF02413.17 AAZ36110.1 - 0.014 15.5 0.0 0.016 15.4 0.0 1.1 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK AMP-binding PF00501.28 AAZ36111.1 - 2e-108 362.7 0.0 2.4e-108 362.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAZ36111.1 - 1.3e-20 74.1 0.9 7.7e-20 71.7 0.6 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.6 AAZ36111.1 - 0.013 15.8 0.0 0.025 14.9 0.0 1.5 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain DUF3851 PF12962.7 AAZ36111.1 - 0.038 14.3 0.0 0.17 12.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3851) DUF4129 PF13559.6 AAZ36112.1 - 4.3e-06 26.9 0.3 1.3e-05 25.3 0.3 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) Polysacc_deac_1 PF01522.21 AAZ36113.1 - 6e-12 45.5 0.0 1.4e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase ATP-sulfurylase PF01747.17 AAZ36113.1 - 0.12 11.8 0.1 0.22 11.0 0.1 1.4 1 0 0 1 1 1 0 ATP-sulfurylase PGI PF00342.19 AAZ36114.1 - 3.1e-190 632.9 0.0 3.6e-190 632.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase DUF4473 PF14747.6 AAZ36114.1 - 0.21 12.2 0.3 0.42 11.2 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) UPF0061 PF02696.14 AAZ36115.1 - 3.2e-151 504.3 0.0 3.6e-151 504.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family AvrB_AvrC PF05394.11 AAZ36116.1 - 4.9e-148 492.6 0.2 5.4e-148 492.5 0.2 1.0 1 0 0 1 1 1 1 Avirulence protein CbiJ PF02571.14 AAZ36117.1 - 2.6e-56 190.7 0.0 3e-56 190.6 0.0 1.0 1 0 0 1 1 1 1 Precorrin-6x reductase CbiJ/CobK DNA_binding_1 PF01035.20 AAZ36118.1 - 1.7e-19 69.7 0.0 2.1e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain CesT PF05932.13 AAZ36119.1 - 1.3e-09 38.2 1.0 1.4e-09 38.0 1.0 1.1 1 0 0 1 1 1 1 Tir chaperone protein (CesT) family HATPase_c PF02518.26 AAZ36120.1 - 5.2e-23 81.7 0.0 8e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 AAZ36120.1 - 1.2e-15 57.7 0.3 2.5e-14 53.4 0.1 2.5 2 0 0 2 2 2 1 HAMP domain HisKA PF00512.25 AAZ36120.1 - 3.4e-13 49.4 1.3 2.5e-12 46.6 0.1 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 AAZ36120.1 - 1.6e-05 24.8 0.1 0.0001 22.2 0.1 2.2 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain HemY_N PF07219.13 AAZ36120.1 - 0.055 13.7 4.6 0.26 11.5 0.6 2.6 2 0 0 2 2 2 0 HemY protein N-terminus FtsX PF02687.21 AAZ36120.1 - 0.54 10.8 3.8 0.86 10.1 0.3 2.2 2 0 0 2 2 2 0 FtsX-like permease family PhnG PF06754.12 AAZ36121.1 - 4.8e-53 178.9 4.3 5.5e-53 178.7 4.3 1.0 1 0 0 1 1 1 1 Phosphonate metabolism protein PhnG PepSY PF03413.19 AAZ36122.1 - 2.8e-09 37.4 0.1 3.6e-09 37.0 0.1 1.1 1 0 0 1 1 1 1 Peptidase propeptide and YPEB domain Phage_TAC_10 PF10963.8 AAZ36123.1 - 8.4e-25 86.8 0.4 9.6e-25 86.6 0.4 1.0 1 0 0 1 1 1 1 Phage tail assembly chaperone Amidohydro_1 PF01979.20 AAZ36124.1 - 1.5e-79 267.9 0.1 1.9e-79 267.5 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 AAZ36124.1 - 3.8e-56 188.6 3.6 7e-56 187.8 3.6 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Amidohydro_3 PF07969.11 AAZ36124.1 - 3.8e-12 46.4 0.7 8.7e-08 32.1 0.0 2.4 2 1 0 2 2 2 2 Amidohydrolase family CorA PF01544.18 AAZ36125.1 - 9.2e-35 120.4 0.2 1.2e-34 120.0 0.2 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein N_methyl PF07963.12 AAZ36126.1 - 2.6e-06 26.8 5.5 4.3e-06 26.1 5.5 1.3 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif GspH PF12019.8 AAZ36126.1 - 0.054 13.9 0.2 0.62 10.5 0.2 2.0 1 1 0 1 1 1 0 Type II transport protein GspH Peptidase_M17_N PF02789.17 AAZ36126.1 - 0.14 12.0 0.1 0.19 11.6 0.1 1.2 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain Multi_Drug_Res PF00893.19 AAZ36127.1 - 1.1e-24 86.9 10.2 1.4e-24 86.6 10.2 1.2 1 0 0 1 1 1 1 Small Multidrug Resistance protein EamA PF00892.20 AAZ36127.1 - 0.0036 17.5 14.9 0.0054 16.9 14.9 1.4 1 1 0 1 1 1 1 EamA-like transporter family Herpes_LMP1 PF05297.11 AAZ36127.1 - 4 6.5 5.6 4.6 6.3 5.6 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) AAA_22 PF13401.6 AAZ36128.1 - 1.1e-11 45.2 0.2 3.3e-11 43.6 0.1 1.7 2 0 0 2 2 2 1 AAA domain SPOR PF05036.13 AAZ36128.1 - 3.3e-11 43.4 0.2 1.3e-10 41.5 0.2 2.1 1 0 0 1 1 1 1 Sporulation related domain AAA_30 PF13604.6 AAZ36128.1 - 3.6e-06 26.8 0.6 6.4e-06 26.0 0.6 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAZ36128.1 - 3.3e-05 24.3 3.4 0.0045 17.4 3.4 2.6 1 1 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 AAZ36128.1 - 0.0076 15.3 0.2 0.019 14.0 0.2 1.6 1 1 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.29 AAZ36128.1 - 0.018 15.5 0.0 0.03 14.7 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 AAZ36128.1 - 0.041 13.8 0.0 0.39 10.6 0.0 2.1 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Sigma54_activ_2 PF14532.6 AAZ36128.1 - 0.088 12.9 0.9 0.23 11.5 0.9 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 AAZ36128.1 - 0.1 12.5 0.6 0.21 11.5 0.6 1.6 1 1 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 AAZ36128.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_2 PF07724.14 AAZ36128.1 - 0.13 12.4 0.0 8.2 6.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) DUF2075 PF09848.9 AAZ36128.1 - 0.22 10.8 0.1 0.29 10.3 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_35 PF14516.6 AAZ36128.1 - 0.23 10.2 0.0 0.36 9.6 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain ABC_tran PF00005.27 AAZ36129.1 - 1.8e-45 154.8 0.0 7.8e-23 81.5 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 AAZ36129.1 - 2.6e-12 47.2 1.2 0.00015 21.7 0.0 3.2 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AAZ36129.1 - 0.00082 19.1 0.9 0.015 15.0 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AAZ36129.1 - 0.00094 19.6 1.3 0.0048 17.3 0.8 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 AAZ36129.1 - 0.0019 17.9 2.4 0.043 13.5 0.8 3.1 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.19 AAZ36129.1 - 0.0036 16.8 0.0 4 6.8 0.2 2.5 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 AAZ36129.1 - 0.0066 16.4 0.1 0.019 14.8 0.1 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 AAZ36129.1 - 0.062 13.8 0.1 0.11 12.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 AAZ36129.1 - 0.064 13.7 0.0 0.46 10.9 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 AAZ36129.1 - 0.078 13.1 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 AAZ36129.1 - 0.12 11.7 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.6 AAZ36129.1 - 0.13 12.4 0.1 0.88 9.7 0.1 2.2 1 1 0 1 1 1 0 AAA domain Cadherin_3 PF16184.5 AAZ36129.1 - 0.15 12.1 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Cadherin-like MerR_2 PF13591.6 AAZ36129.1 - 0.18 11.7 0.4 9 6.2 0.0 2.6 2 0 0 2 2 2 0 MerR HTH family regulatory protein Thioredoxin PF00085.20 AAZ36130.1 - 9.7e-27 93.0 0.0 1.5e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin TPR_20 PF14561.6 AAZ36130.1 - 1.4e-26 92.6 2.2 1.4e-26 92.6 2.2 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 AAZ36130.1 - 4e-12 46.5 20.3 2.5e-11 43.9 7.6 2.6 3 0 0 3 3 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 AAZ36130.1 - 1e-07 32.1 3.2 4.8e-05 23.5 0.1 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 Thioredoxin_2 PF13098.6 AAZ36130.1 - 1.7e-07 31.7 0.1 1.3e-06 28.8 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 AAZ36130.1 - 4.4e-06 26.9 0.0 5.8e-05 23.3 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin-like TPR_16 PF13432.6 AAZ36130.1 - 0.00083 20.0 8.7 0.00083 20.0 8.7 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat AhpC-TSA PF00578.21 AAZ36130.1 - 0.0011 18.9 0.1 0.0026 17.7 0.1 1.6 1 1 0 1 1 1 1 AhpC/TSA family TPR_17 PF13431.6 AAZ36130.1 - 0.0018 18.5 3.9 0.28 11.7 0.5 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 AAZ36130.1 - 0.0027 18.4 14.4 0.037 14.8 2.2 4.3 1 1 3 5 5 5 2 Tetratricopeptide repeat OST3_OST6 PF04756.13 AAZ36130.1 - 0.0036 16.7 0.0 0.0047 16.3 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 AAZ36130.1 - 0.0056 16.7 0.0 0.0099 15.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin domain Sec16_C PF12931.7 AAZ36130.1 - 0.012 15.3 0.1 0.018 14.7 0.1 1.2 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 TraF PF13728.6 AAZ36130.1 - 0.019 14.8 0.6 0.034 14.0 0.0 1.7 2 0 0 2 2 2 0 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 AAZ36130.1 - 0.02 15.1 0.1 0.051 13.8 0.1 1.8 1 0 0 1 1 1 0 Thioredoxin-like HyaE PF07449.11 AAZ36130.1 - 0.025 14.5 0.0 0.051 13.6 0.0 1.5 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE HrpB1_HrpK PF09613.10 AAZ36130.1 - 0.061 13.0 3.6 0.056 13.1 1.0 2.1 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) IBN_N PF03810.19 AAZ36130.1 - 0.12 12.3 0.4 0.24 11.3 0.4 1.5 1 0 0 1 1 1 0 Importin-beta N-terminal domain Alkyl_sulf_dimr PF14863.6 AAZ36130.1 - 0.17 12.4 3.1 1.4 9.4 0.7 2.3 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation TPR_21 PF09976.9 AAZ36130.1 - 2 8.1 13.5 0.39 10.4 7.1 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain AdoMet_dc PF02675.15 AAZ36131.1 - 8.3e-32 109.6 0.0 1.6e-31 108.7 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine decarboxylase Phos_pyr_kin PF08543.12 AAZ36132.1 - 5.1e-12 45.7 0.0 6.1e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 AAZ36132.1 - 1.1e-09 38.0 0.1 4.8e-09 35.9 0.0 2.0 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Mem_trans PF03547.18 AAZ36133.1 - 1.4e-20 73.0 28.3 8.7e-13 47.4 13.4 2.0 2 0 0 2 2 2 2 Membrane transport protein SBF PF01758.16 AAZ36133.1 - 0.0015 18.2 6.7 0.0015 18.2 6.7 2.6 1 1 1 2 2 2 2 Sodium Bile acid symporter family DUF4357 PF14267.6 AAZ36133.1 - 0.0032 17.4 0.2 0.0087 16.0 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4357) FMN_red PF03358.15 AAZ36134.1 - 5.2e-37 127.0 0.0 7e-37 126.6 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 AAZ36134.1 - 3.3e-05 23.7 0.0 4.7e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold CheW PF01584.19 AAZ36135.1 - 1.5e-37 128.3 0.5 1.8e-37 128.1 0.5 1.1 1 0 0 1 1 1 1 CheW-like domain DUF2388 PF09498.10 AAZ36136.1 - 1.3e-30 105.2 0.1 1.6e-30 104.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2388) PV_NSP1 PF12433.8 AAZ36136.1 - 0.069 13.5 0.0 0.088 13.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein 1 ADK PF00406.22 AAZ36137.1 - 5.6e-55 185.6 0.0 6.8e-55 185.3 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 AAZ36137.1 - 4e-24 85.6 0.1 6.5e-24 84.9 0.1 1.3 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 AAZ36137.1 - 9.1e-16 57.6 0.2 2.3e-15 56.3 0.1 1.8 2 0 0 2 2 2 1 Adenylate kinase, active site lid Hydin_ADK PF17213.3 AAZ36137.1 - 1.4e-05 25.5 0.3 0.039 14.2 0.1 2.4 1 1 1 2 2 2 2 Hydin Adenylate kinase-like domain AAA_18 PF13238.6 AAZ36137.1 - 0.00093 19.8 0.0 0.0078 16.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AAZ36137.1 - 0.042 14.0 0.0 0.091 12.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 AAZ36137.1 - 0.042 13.6 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase DarT PF14487.6 AAZ36137.1 - 0.14 11.9 0.0 0.41 10.5 0.0 1.6 1 1 0 2 2 2 0 ssDNA thymidine ADP-ribosyltransferase, DarT AAA_28 PF13521.6 AAZ36137.1 - 0.16 12.2 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain MCPsignal PF00015.21 AAZ36138.1 - 4.4e-43 147.1 25.6 4.4e-43 147.1 25.6 4.2 3 1 1 4 4 4 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HBM PF16591.5 AAZ36138.1 - 8.4e-39 133.5 9.8 8.4e-39 133.5 9.8 3.6 2 1 2 4 4 4 1 Helical bimodular sensor domain 4HB_MCP_1 PF12729.7 AAZ36138.1 - 7.5e-09 35.4 0.5 7.5e-09 35.4 0.5 5.6 3 2 2 5 5 5 1 Four helix bundle sensory module for signal transduction HAMP PF00672.25 AAZ36138.1 - 5.3e-08 33.1 0.2 5.3e-08 33.1 0.2 5.2 6 0 0 6 6 6 1 HAMP domain DUF745 PF05335.13 AAZ36138.1 - 0.0038 17.0 11.6 0.0038 17.0 11.6 4.1 4 1 0 4 4 3 1 Protein of unknown function (DUF745) DUF948 PF06103.11 AAZ36138.1 - 0.018 15.3 5.8 0.018 15.3 5.8 6.1 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF948) Robl_LC7 PF03259.17 AAZ36138.1 - 0.16 11.8 0.2 0.16 11.8 0.2 3.1 2 1 1 3 3 3 0 Roadblock/LC7 domain Laminin_II PF06009.12 AAZ36138.1 - 0.52 10.3 30.4 0.44 10.6 9.4 3.4 3 0 0 3 3 3 0 Laminin Domain II Fez1 PF06818.15 AAZ36138.1 - 0.53 10.7 13.6 0.96 9.9 4.7 2.7 2 0 0 2 2 2 0 Fez1 Spc7 PF08317.11 AAZ36138.1 - 0.63 8.9 15.6 0.71 8.7 5.1 2.7 2 0 0 2 2 2 0 Spc7 kinetochore protein ZapB PF06005.12 AAZ36138.1 - 1.3 9.5 15.3 1.7 9.1 0.6 4.4 5 1 0 5 5 4 0 Cell division protein ZapB Med29 PF11568.8 AAZ36138.1 - 2.3 8.5 7.4 1 9.6 0.8 3.2 3 0 0 3 3 3 0 Mediator complex subunit 29 TMPIT PF07851.13 AAZ36138.1 - 4.6 6.4 11.5 0.99 8.6 1.4 3.1 3 0 0 3 3 3 0 TMPIT-like protein FlaC_arch PF05377.11 AAZ36138.1 - 4.7 7.7 11.8 15 6.1 0.3 4.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) BLOC1_2 PF10046.9 AAZ36138.1 - 7.7 6.9 21.7 3 8.2 0.3 5.7 6 1 1 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 tRNA-synt_1 PF00133.22 AAZ36139.1 - 8.6e-69 232.3 0.0 7.3e-46 156.6 0.3 5.7 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 AAZ36139.1 - 1e-68 230.5 0.0 1.7e-68 229.8 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 AAZ36139.1 - 6.6e-29 100.8 0.0 4.7e-19 68.4 0.0 4.4 3 1 1 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 AAZ36139.1 - 7.8e-17 61.6 0.0 1.4e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 AAZ36139.1 - 0.00014 21.3 0.0 0.51 9.6 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 AAZ36139.1 - 0.0061 15.5 0.0 2.4 7.0 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (K) FRB_dom PF08771.11 AAZ36139.1 - 0.087 13.2 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 FKBP12-rapamycin binding domain tRNA-synt_1d PF00750.19 AAZ36139.1 - 0.13 11.2 0.0 0.24 10.3 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (R) zf-ribbon_3 PF13248.6 AAZ36139.1 - 0.85 9.1 6.5 4.2 6.9 1.9 2.5 2 0 0 2 2 2 0 zinc-ribbon domain NUP PF06516.11 AAZ36140.1 - 3.7e-126 420.6 0.0 4.2e-126 420.4 0.0 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) PNP_UDP_1 PF01048.20 AAZ36140.1 - 0.086 12.1 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphorylase superfamily RapA_C PF12137.8 AAZ36141.1 - 2.9e-139 464.1 0.4 7.6e-139 462.7 0.2 1.7 2 0 0 2 2 2 1 RNA polymerase recycling family C-terminal Tudor_1_RapA PF18339.1 AAZ36141.1 - 1.4e-23 82.6 0.0 3e-23 81.5 0.0 1.7 1 0 0 1 1 1 1 RapA N-terminal Tudor like domain 1 Tudor_RapA PF18337.1 AAZ36141.1 - 2.1e-21 75.8 0.2 8.7e-21 73.9 0.0 2.2 2 0 0 2 2 2 1 RapA N-terminal Tudor like domain SNF2_N PF00176.23 AAZ36141.1 - 2e-15 56.4 0.0 3.3e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 AAZ36141.1 - 1.6e-12 47.7 0.0 3.8e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 AAZ36141.1 - 2.9e-09 37.2 0.0 5.1e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 AAZ36141.1 - 0.00034 20.4 0.0 0.001 18.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase MaoC_dehydratas PF01575.19 AAZ36142.1 - 1.6e-27 95.5 0.0 1.9e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 AAZ36142.1 - 5.4e-06 26.6 0.0 7.9e-06 26.0 0.0 1.3 1 1 0 1 1 1 1 N-terminal half of MaoC dehydratase FabA PF07977.13 AAZ36142.1 - 0.0059 16.2 0.0 0.0085 15.7 0.0 1.2 1 0 0 1 1 1 1 FabA-like domain Lipocalin_2 PF08212.12 AAZ36144.1 - 5.9e-60 201.4 0.3 6.9e-60 201.2 0.3 1.0 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 AAZ36144.1 - 8.2e-06 26.1 0.0 1.2e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Bac_luciferase PF00296.20 AAZ36145.1 - 1.8e-36 126.2 0.1 2.3e-36 125.8 0.1 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase adh_short_C2 PF13561.6 AAZ36146.1 - 4.3e-64 216.3 4.5 5.1e-64 216.0 4.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAZ36146.1 - 8.8e-51 172.1 1.8 1e-50 171.9 1.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAZ36146.1 - 9.1e-10 38.7 2.2 1.4e-09 38.1 2.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AAZ36146.1 - 1.6e-05 24.5 0.5 2.1e-05 24.1 0.5 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 AAZ36146.1 - 9.8e-05 21.6 0.3 0.00014 21.0 0.3 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain HI0933_like PF03486.14 AAZ36146.1 - 0.0043 15.8 0.1 0.007 15.1 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein YjfB_motility PF14070.6 AAZ36146.1 - 0.0065 16.6 0.1 0.02 15.0 0.0 1.9 2 0 0 2 2 2 1 Putative motility protein NAD_binding_8 PF13450.6 AAZ36146.1 - 0.015 15.5 0.2 0.046 14.0 0.2 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AAZ36146.1 - 0.048 13.2 1.5 0.22 11.1 0.7 2.0 1 1 1 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 AAZ36146.1 - 0.084 12.1 0.8 0.12 11.5 0.8 1.2 1 0 0 1 1 1 0 FAD binding domain HlyD_D23 PF16576.5 AAZ36147.1 - 2.4e-14 53.1 5.2 2.9e-14 52.8 3.4 1.9 2 0 0 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AAZ36147.1 - 7e-14 52.4 0.3 2.1e-10 41.3 0.3 2.7 2 1 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AAZ36147.1 - 3.7e-11 42.7 0.1 4.1e-06 26.5 0.0 2.9 2 0 0 2 2 2 2 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AAZ36147.1 - 0.00078 19.2 0.0 1.8 8.4 0.0 2.9 3 0 0 3 3 3 2 Biotin-requiring enzyme Glyco_hydro_65N PF03636.15 AAZ36147.1 - 0.045 13.4 0.1 0.087 12.4 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain DUF2118 PF09891.9 AAZ36147.1 - 0.083 12.8 0.3 0.3 11.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) Amino_oxidase PF01593.24 AAZ36148.1 - 1.2e-42 146.8 0.0 1.6e-42 146.4 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 AAZ36148.1 - 1.3e-10 41.4 0.4 3.8e-10 39.9 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AAZ36148.1 - 0.00022 20.9 0.1 0.0013 18.4 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AAZ36148.1 - 0.0003 20.0 0.4 0.00044 19.5 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 AAZ36148.1 - 0.0013 18.0 0.4 0.002 17.4 0.4 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 AAZ36148.1 - 0.0019 17.5 0.1 0.003 16.8 0.1 1.2 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 AAZ36148.1 - 0.0029 16.7 0.5 0.0041 16.3 0.5 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 AAZ36148.1 - 0.0081 15.5 0.3 0.013 14.8 0.3 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 AAZ36148.1 - 0.0092 14.7 0.9 0.013 14.2 0.9 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 AAZ36148.1 - 0.013 14.8 1.2 0.023 13.9 1.2 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 AAZ36148.1 - 0.03 13.6 0.4 0.06 12.6 0.4 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 AAZ36148.1 - 0.033 12.6 0.0 0.053 11.9 0.0 1.3 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like FAD_oxidored PF12831.7 AAZ36148.1 - 0.17 11.2 0.3 0.26 10.6 0.3 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Amidohydro_1 PF01979.20 AAZ36149.1 - 7.8e-70 235.9 0.0 9.1e-70 235.7 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AAZ36149.1 - 1.2e-16 61.2 0.0 2.9e-12 46.8 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family GXGXG PF01493.19 AAZ36150.1 - 7.6e-12 45.2 12.1 1.3e-11 44.4 12.1 1.4 1 1 0 1 1 1 1 GXGXG motif DUF4479 PF14794.6 AAZ36150.1 - 0.064 13.1 0.7 3.2 7.7 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4479) Acyltransferase PF01553.21 AAZ36151.1 - 8.3e-15 54.6 0.0 1.2e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase T2SSK PF03934.13 AAZ36152.1 - 6.7e-08 32.3 9.5 0.00011 21.7 6.0 2.2 1 1 1 2 2 2 2 Type II secretion system (T2SS), protein K PilX_N PF14341.6 AAZ36152.1 - 0.0064 16.4 1.6 0.0069 16.3 0.3 1.8 2 0 0 2 2 2 1 PilX N-terminal Peripla_BP_4 PF13407.6 AAZ36153.1 - 2.8e-58 197.5 12.6 3.3e-58 197.3 12.6 1.0 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 AAZ36153.1 - 2.1e-25 89.7 1.9 2.5e-25 89.5 1.9 1.0 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_3 PF13377.6 AAZ36153.1 - 3.5e-11 43.7 0.1 3.4e-10 40.5 0.0 2.0 2 0 0 2 2 2 1 Periplasmic binding protein-like domain TraO PF10626.9 AAZ36153.1 - 0.039 13.7 0.0 0.068 12.9 0.0 1.3 1 0 0 1 1 1 0 Conjugative transposon protein TraO Mannitol_dh PF01232.23 AAZ36153.1 - 0.12 12.6 0.1 0.35 11.0 0.0 1.9 2 1 0 2 2 2 0 Mannitol dehydrogenase Rossmann domain POR PF01558.18 AAZ36154.1 - 5.9e-22 78.6 0.7 1e-21 77.8 0.7 1.4 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase TPP_enzyme_C PF02775.21 AAZ36154.1 - 2e-05 24.4 0.4 4.9e-05 23.2 0.4 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Mt_ATP_synt PF15704.5 AAZ36154.1 - 0.061 13.2 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase subunit S-AdoMet_synt_C PF02773.16 AAZ36155.1 - 2.8e-66 221.7 0.1 5.3e-66 220.8 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 AAZ36155.1 - 8.7e-44 148.6 0.0 2.6e-43 147.1 0.0 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 AAZ36155.1 - 1.2e-40 138.2 0.3 2.3e-40 137.3 0.3 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain CadC_C1 PF18500.1 AAZ36155.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 CadC C-terminal domain 1 EFP_N PF08207.12 AAZ36156.1 - 1.2e-20 73.3 0.0 2.2e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Elong-fact-P_C PF09285.11 AAZ36156.1 - 2.4e-17 62.4 0.1 7.4e-17 60.9 0.1 1.9 1 0 0 1 1 1 1 Elongation factor P, C-terminal EFP PF01132.20 AAZ36156.1 - 1.6e-12 47.2 0.9 3.4e-12 46.2 0.9 1.6 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain adh_short_C2 PF13561.6 AAZ36157.1 - 1.9e-67 227.3 0.4 2.1e-67 227.1 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAZ36157.1 - 1e-44 152.4 0.0 1.4e-44 151.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAZ36157.1 - 8.6e-09 35.6 1.1 1.8e-08 34.5 1.2 1.4 1 1 0 1 1 1 1 KR domain YAcAr PF10686.9 AAZ36157.1 - 0.024 14.6 0.2 0.062 13.3 0.2 1.7 1 0 0 1 1 1 0 YspA, cpYpsA-related SLOG family DUF3412 PF11892.8 AAZ36158.1 - 9.1e-57 190.4 0.0 1.6e-56 189.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3412) DUF4478 PF14793.6 AAZ36158.1 - 9e-43 144.6 0.0 2.6e-42 143.1 0.0 1.8 2 0 0 2 2 2 1 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidases Lysine_decarbox PF03641.14 AAZ36158.1 - 3.2e-31 108.1 0.1 1e-30 106.5 0.0 1.9 2 0 0 2 2 2 1 Possible lysine decarboxylase LDcluster4 PF18306.1 AAZ36158.1 - 4e-06 26.5 0.1 7.4e-06 25.6 0.1 1.3 1 0 0 1 1 1 1 SLOG cluster4 family MotA_ExbB PF01618.16 AAZ36159.1 - 8.6e-27 93.4 1.0 1.4e-26 92.8 0.1 1.7 1 1 0 2 2 2 1 MotA/TolQ/ExbB proton channel family PALP PF00291.25 AAZ36160.1 - 1.1e-13 51.2 0.4 1.6e-13 50.7 0.4 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ATP-grasp_3 PF02655.14 AAZ36161.1 - 1.5e-11 44.6 0.0 2.9e-10 40.4 0.0 2.3 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 AAZ36161.1 - 5.2e-11 42.4 0.0 1.3e-09 37.8 0.0 2.2 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 AAZ36161.1 - 8.2e-05 22.2 0.0 0.24 10.9 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.6 AAZ36161.1 - 0.00015 21.5 0.2 0.00059 19.6 0.1 2.1 2 1 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.13 AAZ36161.1 - 0.00071 19.2 0.0 0.18 11.3 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_N PF18130.1 AAZ36161.1 - 0.069 13.7 0.0 0.2 12.2 0.0 1.8 1 1 0 1 1 1 0 ATP-grasp N-terminal domain MurB_C PF02873.16 AAZ36162.1 - 2.2e-35 121.3 0.0 5.2e-35 120.1 0.0 1.6 2 0 0 2 2 2 1 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain FAD_binding_4 PF01565.23 AAZ36162.1 - 1.4e-25 89.7 0.0 2.5e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_synthase PF02540.17 AAZ36163.1 - 9.8e-63 211.5 0.0 1.2e-62 211.2 0.0 1.1 1 0 0 1 1 1 1 NAD synthase VitD-bind_III PF09164.10 AAZ36163.1 - 0.12 12.4 0.5 0.37 10.8 0.1 1.9 2 0 0 2 2 2 0 Vitamin D binding protein, domain III Transposase_mut PF00872.18 AAZ36164.1 - 2.8e-117 391.8 0.0 3.4e-117 391.5 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ36164.1 - 7.7e-05 23.0 0.0 0.00021 21.6 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain DUF4844 PF16133.5 AAZ36164.1 - 0.23 12.0 0.0 0.55 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) CPSase_L_D2 PF02786.17 AAZ36165.1 - 2.6e-80 268.9 0.0 4.6e-80 268.1 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 AAZ36165.1 - 1.7e-44 150.8 0.1 6.9e-44 148.9 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 AAZ36165.1 - 6.8e-39 132.3 0.0 1.3e-38 131.3 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 AAZ36165.1 - 2.3e-08 33.8 0.0 6.4e-08 32.4 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 AAZ36165.1 - 3.6e-07 29.9 0.0 7.7e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 AAZ36165.1 - 6.9e-06 26.2 0.0 1.6e-05 25.0 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain LAL_C2 PF18603.1 AAZ36165.1 - 0.00078 19.6 0.0 0.0023 18.0 0.0 1.8 1 0 0 1 1 1 1 L-amino acid ligase C-terminal domain 2 ATP-grasp_4 PF13535.6 AAZ36165.1 - 0.0071 16.0 0.0 0.054 13.1 0.0 2.4 2 1 1 3 3 3 1 ATP-grasp domain GARS_A PF01071.19 AAZ36165.1 - 0.022 14.5 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Autotransporter PF03797.19 AAZ36166.1 - 2e-48 165.3 14.0 2e-48 165.3 14.0 3.5 5 0 0 5 5 5 1 Autotransporter beta-domain Pertactin PF03212.14 AAZ36166.1 - 3.5e-25 88.3 0.3 3.5e-25 88.3 0.3 2.7 3 0 0 3 3 3 1 Pertactin HTH_18 PF12833.7 AAZ36167.1 - 1.3e-23 83.0 0.1 2.8e-23 82.0 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAZ36167.1 - 8.6e-17 60.8 0.1 6.7e-08 32.4 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_23 PF13384.6 AAZ36167.1 - 0.0026 17.5 0.0 0.0068 16.2 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain DJ-1_PfpI PF01965.24 AAZ36167.1 - 0.057 13.2 0.0 0.095 12.5 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family HTH_Crp_2 PF13545.6 AAZ36167.1 - 0.062 13.3 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Rrf2 PF02082.20 AAZ36167.1 - 0.086 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator HTH_Tnp_1_2 PF13022.6 AAZ36167.1 - 0.16 12.2 0.1 0.31 11.2 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase DTW PF03942.15 AAZ36168.1 - 2e-44 151.7 0.0 2.4e-44 151.5 0.0 1.0 1 0 0 1 1 1 1 DTW domain Mago-bind PF09282.10 AAZ36168.1 - 0.016 15.1 0.2 0.036 13.9 0.2 1.6 1 0 0 1 1 1 0 Mago binding PC_rep PF01851.22 AAZ36168.1 - 0.17 12.4 0.3 1.5 9.4 0.1 2.4 2 0 0 2 2 2 0 Proteasome/cyclosome repeat Toluene_X PF03349.16 AAZ36169.1 - 4.5e-114 381.4 6.9 5.3e-114 381.1 6.9 1.0 1 0 0 1 1 1 1 Outer membrane protein transport protein (OMPP1/FadL/TodX) Porin_2 PF02530.14 AAZ36169.1 - 2.1e-05 24.0 1.8 0.00024 20.5 0.2 2.2 2 0 0 2 2 2 1 Porin subfamily YadA_anchor PF03895.15 AAZ36169.1 - 0.00031 20.8 0.6 0.0097 16.0 0.0 3.7 4 0 0 4 4 4 1 YadA-like membrane anchor domain DUF2490 PF10677.9 AAZ36169.1 - 0.00042 20.3 0.8 2.6 8.0 0.0 3.7 2 2 0 2 2 2 2 Protein of unknown function (DUF2490) BBP2 PF07642.11 AAZ36169.1 - 0.013 14.7 10.3 0.36 9.9 9.1 2.6 2 1 0 2 2 2 0 Putative beta-barrel porin-2, OmpL-like. bbp2 L_biotic_typeA PF04604.13 AAZ36169.1 - 0.18 11.7 0.1 0.34 10.8 0.1 1.4 1 0 0 1 1 1 0 Type-A lantibiotic YacG PF03884.14 AAZ36170.1 - 5.2e-26 90.1 2.8 5.9e-26 90.0 2.8 1.1 1 0 0 1 1 1 1 DNA gyrase inhibitor YacG zf-ribbon_3 PF13248.6 AAZ36170.1 - 0.21 11.0 2.8 0.22 11.0 1.3 2.0 2 1 0 2 2 2 0 zinc-ribbon domain DUF2256 PF10013.9 AAZ36170.1 - 0.24 11.5 2.9 13 6.0 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) Topoisom_bac PF01131.20 AAZ36171.1 - 5.5e-115 384.7 0.0 6.6e-115 384.4 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 AAZ36171.1 - 5.9e-18 65.0 0.0 1.2e-17 64.1 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.6 AAZ36171.1 - 0.0013 19.1 0.0 0.003 18.0 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Toprim_2 PF13155.6 AAZ36171.1 - 0.0032 17.8 0.0 0.0081 16.6 0.0 1.6 1 0 0 1 1 1 1 Toprim-like NYN PF01936.18 AAZ36172.1 - 1.2e-37 129.6 0.1 1.4e-37 129.4 0.1 1.0 1 0 0 1 1 1 1 NYN domain Peptidase_C71 PF12386.8 AAZ36172.1 - 0.015 15.0 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Pseudomurein endo-isopeptidase Pei Acetyltransf_3 PF13302.7 AAZ36173.1 - 3.9e-24 85.9 0.0 4.6e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAZ36173.1 - 2.2e-06 27.9 0.0 2.8e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 AAZ36173.1 - 0.00085 19.5 0.0 0.001 19.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 AAZ36173.1 - 0.048 13.4 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Thr_synth_N PF14821.6 AAZ36174.1 - 1.2e-30 105.5 0.0 5e-30 103.5 0.0 2.1 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.25 AAZ36174.1 - 3e-24 85.9 0.0 1.4e-23 83.8 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF2789 PF10982.8 AAZ36175.1 - 2.4e-31 107.7 1.5 2.8e-31 107.5 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2789) AAA_lid_2 PF17863.1 AAZ36176.1 - 3e-20 71.8 1.8 6.3e-20 70.8 1.8 1.6 1 0 0 1 1 1 1 AAA lid domain AAA_5 PF07728.14 AAZ36176.1 - 6.9e-12 45.5 0.0 9.9e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 AAZ36176.1 - 3.5e-09 36.4 0.4 1.9e-06 27.5 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI MCM PF00493.23 AAZ36176.1 - 2.2e-08 33.5 0.0 3.5e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain Sigma54_activat PF00158.26 AAZ36176.1 - 1.7e-05 24.6 0.0 3.1e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 AAZ36176.1 - 0.0023 18.4 1.1 0.0056 17.1 1.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 AAZ36176.1 - 0.0064 16.9 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Caskin-Pro-rich PF16907.5 AAZ36176.1 - 0.031 14.8 0.5 0.065 13.8 0.5 1.6 1 0 0 1 1 1 0 Proline rich region of Caskin proteins AAA_3 PF07726.11 AAZ36176.1 - 0.031 14.1 0.0 0.066 13.1 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 AAZ36176.1 - 0.035 13.8 0.2 0.55 10.0 0.2 2.2 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 AAZ36176.1 - 0.16 11.9 0.2 0.37 10.7 0.0 1.6 2 0 0 2 2 2 0 NACHT domain AAA_2 PF07724.14 AAZ36176.1 - 0.19 11.8 0.0 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) DUF1307 PF06998.11 AAZ36177.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1307) DJ-1_PfpI PF01965.24 AAZ36178.1 - 2e-48 164.3 0.1 2.4e-48 164.0 0.1 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Catalase_C PF18011.1 AAZ36178.1 - 8.3e-06 25.5 0.0 1.3e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 C-terminal domain found in long catalases MctB PF11382.8 AAZ36178.1 - 0.0058 16.4 0.2 0.027 14.2 0.1 2.0 2 1 0 2 2 2 1 Copper transport outer membrane protein, MctB GATase PF00117.28 AAZ36178.1 - 0.054 13.2 0.0 0.15 11.8 0.0 1.6 1 1 1 2 2 2 0 Glutamine amidotransferase class-I DUF4479 PF14794.6 AAZ36178.1 - 0.12 12.3 0.0 0.34 10.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4479) LysR_substrate PF03466.20 AAZ36179.1 - 3.5e-38 131.1 0.2 4.9e-38 130.6 0.2 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ36179.1 - 1.3e-18 66.7 0.1 2.9e-18 65.6 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AAZ36179.1 - 0.0066 16.2 0.3 0.014 15.2 0.1 1.7 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain Methyltransf_32 PF13679.6 AAZ36180.1 - 5e-14 52.6 3.3 1.8e-13 50.8 3.3 1.8 1 1 0 1 1 1 1 Methyltransferase domain TRM13 PF05206.14 AAZ36180.1 - 0.022 14.3 1.4 2.6 7.5 0.0 2.6 2 1 1 3 3 3 0 Methyltransferase TRM13 DUF3482 PF11981.8 AAZ36181.1 - 1.3e-109 366.2 8.0 1.8e-109 365.7 8.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3482) MMR_HSR1 PF01926.23 AAZ36181.1 - 7.7e-18 64.6 0.0 2.5e-17 63.0 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 AAZ36181.1 - 0.00018 21.5 0.4 0.00033 20.6 0.1 1.5 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 AAZ36181.1 - 0.00036 20.1 0.0 0.00071 19.1 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Ras PF00071.22 AAZ36181.1 - 0.021 14.4 0.1 0.049 13.2 0.0 1.6 2 0 0 2 2 2 0 Ras family AIG1 PF04548.16 AAZ36181.1 - 0.023 14.0 0.1 0.054 12.8 0.0 1.6 2 0 0 2 2 2 0 AIG1 family Roc PF08477.13 AAZ36181.1 - 0.024 14.8 0.0 0.046 13.9 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 AAZ36181.1 - 0.05 13.0 0.2 0.33 10.4 0.0 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 AAZ36181.1 - 0.056 13.5 1.3 0.71 9.9 0.1 2.8 2 1 1 3 3 3 0 Dynamin family GTP_EFTU PF00009.27 AAZ36181.1 - 0.081 12.5 0.0 1.4 8.4 0.0 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 AAZ36181.1 - 0.1 13.1 0.0 0.28 11.7 0.0 1.8 2 0 0 2 2 2 0 ABC transporter HSCB_C PF07743.13 AAZ36181.1 - 0.54 10.8 8.2 0.19 12.2 2.1 3.1 2 1 1 3 3 3 0 HSCB C-terminal oligomerisation domain Proton_antipo_M PF00361.20 AAZ36182.1 - 5.2e-64 216.3 23.7 5.2e-64 216.3 23.7 3.2 3 0 0 3 3 3 1 Proton-conducting membrane transporter MnhB PF04039.13 AAZ36182.1 - 5e-33 114.0 12.5 5e-33 114.0 12.5 7.4 6 3 2 8 8 8 1 Domain related to MnhB subunit of Na+/H+ antiporter DUF4040 PF13244.6 AAZ36182.1 - 7.3e-21 74.1 6.6 7.3e-21 74.1 6.6 5.5 6 1 0 6 6 6 1 Domain of unknown function (DUF4040) Proton_antipo_N PF00662.20 AAZ36182.1 - 1.8e-09 37.5 1.2 1.8e-09 37.5 1.2 3.5 4 0 0 4 4 4 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus DUF3391 PF11871.8 AAZ36183.1 - 1.4e-27 96.9 0.0 2.5e-27 96.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3391) HD_5 PF13487.6 AAZ36183.1 - 5.1e-17 61.9 0.0 1.3e-16 60.6 0.0 1.7 1 0 0 1 1 1 1 HD domain HD PF01966.22 AAZ36183.1 - 2.3e-14 53.7 0.1 4.2e-14 52.8 0.1 1.5 1 0 0 1 1 1 1 HD domain HDOD PF08668.12 AAZ36183.1 - 1.9e-05 24.3 0.0 3.3e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 HDOD domain DNA_ligase_A_M PF01068.21 AAZ36184.1 - 6.9e-24 84.6 0.0 1.5e-22 80.2 0.0 2.1 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 AAZ36184.1 - 3.7e-15 56.7 0.0 8e-15 55.6 0.0 1.5 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 AAZ36184.1 - 4e-10 40.2 0.0 1.1e-09 38.8 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region mRNA_cap_enzyme PF01331.19 AAZ36184.1 - 0.013 15.3 0.0 0.2 11.4 0.0 2.2 2 0 0 2 2 2 0 mRNA capping enzyme, catalytic domain BPD_transp_1 PF00528.22 AAZ36185.1 - 8.7e-28 97.3 10.1 8.7e-28 97.3 10.1 1.5 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 AAZ36185.1 - 0.008 16.1 0.0 0.008 16.1 0.0 3.6 4 0 0 4 4 4 1 N-terminal TM domain of oligopeptide transport permease C Shikimate_dh_N PF08501.11 AAZ36186.1 - 1.4e-15 57.3 0.1 4e-15 55.8 0.0 1.8 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 AAZ36186.1 - 0.055 13.5 0.0 0.24 11.5 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase SDH_C PF18317.1 AAZ36186.1 - 0.7 9.7 2.9 0.49 10.2 0.2 2.2 2 0 0 2 2 2 0 Shikimate 5'-dehydrogenase C-terminal domain Exo_endo_phos PF03372.23 AAZ36187.1 - 3.8e-16 59.3 0.3 4.8e-16 59.0 0.3 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 AAZ36187.1 - 0.0076 16.1 0.0 0.035 14.0 0.0 2.0 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase SRP54 PF00448.22 AAZ36188.1 - 1e-77 260.3 2.7 1.6e-77 259.6 2.7 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 AAZ36188.1 - 6.2e-13 48.8 0.4 1.5e-12 47.6 0.4 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain Zeta_toxin PF06414.12 AAZ36188.1 - 1.9e-08 33.8 0.1 2.9e-08 33.2 0.1 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_30 PF13604.6 AAZ36188.1 - 2.3e-05 24.2 1.5 4.1e-05 23.4 1.5 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AAZ36188.1 - 9.1e-05 22.6 0.1 0.00016 21.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 AAZ36188.1 - 0.00013 21.9 0.3 0.00026 20.9 0.0 1.6 2 0 0 2 2 1 1 Adenylylsulphate kinase AAA_17 PF13207.6 AAZ36188.1 - 0.00019 21.8 0.1 0.00042 20.8 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AAZ36188.1 - 0.00048 20.4 0.2 0.0015 18.8 0.2 1.8 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 AAZ36188.1 - 0.00066 19.0 0.4 0.00093 18.5 0.4 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 AAZ36188.1 - 0.0014 19.1 0.1 0.0026 18.3 0.1 1.4 1 0 0 1 1 1 1 ABC transporter MeaB PF03308.16 AAZ36188.1 - 0.0041 16.1 1.2 0.012 14.6 0.4 2.1 1 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_31 PF13614.6 AAZ36188.1 - 0.0056 16.6 0.2 0.013 15.4 0.2 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AAZ36188.1 - 0.0063 17.1 0.2 0.023 15.3 0.2 1.9 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 AAZ36188.1 - 0.0072 16.0 1.1 0.015 15.0 0.3 1.8 2 0 0 2 2 2 1 Thymidylate kinase AAA PF00004.29 AAZ36188.1 - 0.0084 16.5 0.1 0.016 15.6 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 AAZ36188.1 - 0.014 15.5 1.9 0.023 14.8 0.6 2.0 2 1 0 2 2 1 0 50S ribosome-binding GTPase CbiA PF01656.23 AAZ36188.1 - 0.015 15.3 0.5 0.044 13.8 0.5 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 AAZ36188.1 - 0.016 15.6 2.3 0.047 14.1 0.4 2.6 1 1 2 3 3 3 0 AAA ATPase domain AAA_24 PF13479.6 AAZ36188.1 - 0.017 14.9 0.2 0.036 13.8 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 AAZ36188.1 - 0.018 15.1 0.0 0.034 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain VirC1 PF07015.11 AAZ36188.1 - 0.024 13.9 0.1 0.054 12.8 0.0 1.6 2 0 0 2 2 2 0 VirC1 protein Viral_helicase1 PF01443.18 AAZ36188.1 - 0.031 14.0 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 AAZ36188.1 - 0.04 14.2 0.9 0.081 13.3 0.6 1.7 1 1 0 1 1 1 0 AAA domain PIF1 PF05970.14 AAZ36188.1 - 0.075 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase Arf PF00025.21 AAZ36188.1 - 0.12 11.8 0.1 0.22 11.0 0.1 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family Rad17 PF03215.15 AAZ36188.1 - 0.18 11.7 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain NB-ARC PF00931.22 AAZ36188.1 - 0.18 10.9 0.5 0.34 10.0 0.2 1.5 2 0 0 2 2 2 0 NB-ARC domain ATP_bind_1 PF03029.17 AAZ36188.1 - 0.19 11.5 0.4 0.32 10.8 0.4 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein cobW PF02492.19 AAZ36188.1 - 0.19 11.3 1.2 0.4 10.2 1.2 1.5 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AIG1 PF04548.16 AAZ36188.1 - 0.23 10.7 0.6 3.7 6.8 0.0 2.3 2 0 0 2 2 2 0 AIG1 family NTPase_1 PF03266.15 AAZ36188.1 - 0.65 9.9 2.6 0.64 9.9 1.0 1.7 2 0 0 2 2 2 0 NTPase NACHT PF05729.12 AAZ36188.1 - 0.72 9.8 3.8 1 9.3 0.8 2.5 3 0 0 3 3 2 0 NACHT domain BPD_transp_1 PF00528.22 AAZ36189.1 - 3.3e-14 53.0 19.1 3.3e-14 53.0 19.1 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component FecCD PF01032.18 AAZ36190.1 - 5.5e-89 298.2 29.8 6.7e-89 298.0 29.8 1.0 1 0 0 1 1 1 1 FecCD transport family MerR_1 PF13411.6 AAZ36191.1 - 4.5e-19 68.3 0.1 9e-19 67.3 0.1 1.5 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 AAZ36191.1 - 6.3e-13 48.3 1.8 1.1e-12 47.4 0.4 2.2 2 0 0 2 2 2 1 MerR family regulatory protein B12-binding_2 PF02607.17 AAZ36191.1 - 0.002 18.6 0.0 0.0044 17.4 0.0 1.5 1 0 0 1 1 1 1 B12 binding domain HTH_Tnp_1 PF01527.20 AAZ36191.1 - 0.0026 18.0 0.3 0.0094 16.2 0.2 1.8 1 1 1 2 2 2 1 Transposase HTH_28 PF13518.6 AAZ36191.1 - 0.023 14.8 1.2 0.56 10.4 0.2 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_23 PF13384.6 AAZ36191.1 - 0.03 14.1 0.2 0.14 12.0 0.1 2.1 2 0 0 2 2 2 0 Homeodomain-like domain HTH_17 PF12728.7 AAZ36191.1 - 0.14 12.4 0.2 0.97 9.7 0.1 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain Aconitase_C PF00694.19 AAZ36192.1 - 1.3e-38 132.2 0.0 1.7e-38 131.9 0.0 1.1 1 0 0 1 1 1 1 Aconitase C-terminal domain DNase-RNase PF02577.14 AAZ36192.1 - 0.17 11.6 0.0 2.6 7.7 0.0 2.1 2 0 0 2 2 2 0 Bifunctional nuclease Mur_ligase_M PF08245.12 AAZ36193.1 - 1e-21 77.8 0.0 1.4e-21 77.4 0.0 1.2 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase PF01225.25 AAZ36193.1 - 8.3e-20 70.9 0.0 2.2e-19 69.6 0.0 1.8 1 0 0 1 1 1 1 Mur ligase family, catalytic domain Mur_ligase_C PF02875.21 AAZ36193.1 - 1.2e-09 38.3 0.5 3.1e-09 37.0 0.0 2.0 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain LamB_YcsF PF03746.16 AAZ36194.1 - 3.3e-90 301.9 0.0 3.7e-90 301.8 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family YbjM PF11045.8 AAZ36194.1 - 0.064 13.4 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative inner membrane protein of Enterobacteriaceae adh_short_C2 PF13561.6 AAZ36195.1 - 4.9e-40 137.5 0.0 7.4e-40 137.0 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAZ36195.1 - 3.5e-35 121.2 0.0 4.9e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 AAZ36195.1 - 3.1e-13 49.8 0.0 1.5e-12 47.5 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 AAZ36195.1 - 7.1e-11 42.3 1.3 3.7e-10 40.0 1.3 1.8 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 AAZ36195.1 - 3.2e-08 33.7 0.1 4.4e-08 33.2 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 AAZ36195.1 - 0.00023 20.7 0.0 0.0097 15.3 0.0 2.5 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 AAZ36195.1 - 0.00028 20.1 0.0 0.00038 19.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 AAZ36195.1 - 0.033 13.2 0.0 0.049 12.6 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Rhomboid PF01694.22 AAZ36196.1 - 3.5e-20 72.5 17.7 3.5e-20 72.5 17.7 1.4 2 0 0 2 2 2 1 Rhomboid family PhnJ PF06007.11 AAZ36197.1 - 3.9e-147 488.6 0.0 4.7e-147 488.3 0.0 1.0 1 0 0 1 1 1 1 Phosphonate metabolism protein PhnJ TonB_dep_Rec PF00593.24 AAZ36198.1 - 5.2e-37 128.8 33.4 5.3e-37 128.8 28.4 2.5 2 1 1 3 3 3 2 TonB dependent receptor Plug PF07715.15 AAZ36198.1 - 1.1e-15 58.1 0.1 3.6e-15 56.5 0.1 1.9 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain STN PF07660.14 AAZ36198.1 - 4e-08 32.9 0.0 8.8e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 Secretin and TonB N terminus short domain OMP_b-brl_3 PF14905.6 AAZ36198.1 - 0.002 17.2 1.3 0.012 14.6 0.1 2.6 3 0 0 3 3 3 1 Outer membrane protein beta-barrel family OMP_b-brl PF13505.6 AAZ36198.1 - 0.23 11.6 19.8 0.84 9.7 1.9 3.9 1 1 2 3 3 3 0 Outer membrane protein beta-barrel domain His_Phos_1 PF00300.22 AAZ36199.1 - 3e-06 27.0 0.4 3.7e-05 23.5 0.0 2.1 1 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Malate_synthase PF01274.22 AAZ36200.1 - 2.6e-176 587.0 0.0 3e-176 586.7 0.0 1.0 1 0 0 1 1 1 1 Malate synthase PLDc_2 PF13091.6 AAZ36201.1 - 1.7e-43 147.7 0.0 2.2e-23 82.6 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 AAZ36201.1 - 1.3e-08 34.6 0.0 0.0047 17.0 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PP_kinase_C PF13090.6 AAZ36201.1 - 0.0098 15.4 0.0 1.4 8.3 0.0 2.4 2 0 0 2 2 2 2 Polyphosphate kinase C-terminal domain 2 Regulator_TrmB PF11495.8 AAZ36201.1 - 0.045 12.9 0.0 0.3 10.2 0.0 2.1 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB HrpE PF06188.12 AAZ36201.1 - 0.097 12.5 2.4 1.4 8.8 0.1 2.3 2 0 0 2 2 2 0 HrpE/YscL/FliH and V-type ATPase subunit E FAM83 PF07894.12 AAZ36201.1 - 0.14 11.7 0.1 12 5.3 0.0 2.2 2 0 0 2 2 2 0 FAM83 A-H Phosphonate-bd PF12974.7 AAZ36202.1 - 7.3e-32 110.9 0.1 8.8e-32 110.6 0.1 1.1 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 AAZ36202.1 - 5.5e-07 29.7 0.0 1.5e-06 28.3 0.0 1.6 1 1 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.20 AAZ36202.1 - 1e-06 28.4 0.0 2e-06 27.4 0.0 1.4 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Gastrin PF00918.17 AAZ36202.1 - 0.17 12.8 0.0 0.36 11.8 0.0 1.5 1 0 0 1 1 1 0 Gastrin/cholecystokinin family AP_endonuc_2 PF01261.24 AAZ36203.1 - 7.7e-07 28.8 0.0 0.017 14.6 0.0 2.3 1 1 1 2 2 2 2 Xylose isomerase-like TIM barrel Amidase PF01425.21 AAZ36204.1 - 5.9e-99 332.1 0.0 3e-98 329.7 0.0 1.8 1 1 0 1 1 1 1 Amidase Peptidase_M23 PF01551.22 AAZ36205.1 - 3.6e-25 88.0 1.6 7.9e-25 86.9 0.6 1.9 2 1 0 2 2 2 1 Peptidase family M23 DUF4124 PF13511.6 AAZ36205.1 - 3.1e-08 33.8 0.2 8e-08 32.5 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4124) Apocytochr_F_C PF01333.19 AAZ36205.1 - 0.065 13.3 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 Apocytochrome F, C-terminal DEAD PF00270.29 AAZ36206.1 - 9.6e-46 155.7 0.0 7.4e-45 152.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AAZ36206.1 - 5e-26 91.2 0.0 1.7e-25 89.5 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 AAZ36206.1 - 4.4e-06 26.8 0.0 8.4e-06 25.9 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 AAZ36206.1 - 2.1e-05 24.9 0.0 0.27 11.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain UTP25 PF06862.12 AAZ36206.1 - 0.00078 18.3 0.0 2.9 6.6 0.0 3.5 2 1 1 3 3 3 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_30 PF13604.6 AAZ36206.1 - 0.0098 15.6 0.1 0.053 13.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain Acetyltransf_6 PF13480.7 AAZ36207.1 - 0.0022 18.1 0.2 0.0075 16.4 0.1 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF533 PF04391.12 AAZ36208.1 - 5.4e-61 205.3 7.5 5.4e-61 205.3 7.5 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF533) TerB PF05099.13 AAZ36208.1 - 0.0089 16.0 0.8 0.0089 16.0 0.8 2.1 1 1 0 2 2 2 1 Tellurite resistance protein TerB RsbRD_N PF14361.6 AAZ36208.1 - 0.27 12.0 4.0 0.35 11.6 1.9 2.3 2 1 1 3 3 3 0 RsbT co-antagonist protein rsbRD N-terminal domain TrmK PF04816.12 AAZ36209.1 - 5.7e-58 195.8 0.0 6.6e-58 195.6 0.0 1.0 1 0 0 1 1 1 1 tRNA (adenine(22)-N(1))-methyltransferase Methyltransf_18 PF12847.7 AAZ36209.1 - 5.3e-46 156.3 0.0 7.1e-46 155.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AAZ36209.1 - 0.082 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain GIY-YIG PF01541.24 AAZ36210.1 - 5.6e-11 42.6 0.0 6.8e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 GIY-YIG catalytic domain Toluene_X PF03349.16 AAZ36211.1 - 1.8e-101 339.8 8.8 2.5e-101 339.4 8.8 1.2 1 0 0 1 1 1 1 Outer membrane protein transport protein (OMPP1/FadL/TodX) OMP_b-brl PF13505.6 AAZ36211.1 - 5.4e-08 33.2 11.3 0.0075 16.4 3.1 3.5 1 1 3 4 4 4 3 Outer membrane protein beta-barrel domain DUF2490 PF10677.9 AAZ36211.1 - 8.3e-05 22.6 0.5 0.043 13.8 0.6 3.3 2 1 0 2 2 2 1 Protein of unknown function (DUF2490) OmpA_membrane PF01389.17 AAZ36211.1 - 0.0014 18.4 1.7 0.0026 17.5 0.1 2.2 2 1 0 2 2 2 1 OmpA-like transmembrane domain BBP2 PF07642.11 AAZ36211.1 - 0.0039 16.4 3.9 0.13 11.4 1.2 2.7 2 1 0 2 2 2 1 Putative beta-barrel porin-2, OmpL-like. bbp2 Usher PF00577.20 AAZ36211.1 - 0.0079 15.1 0.1 0.014 14.2 0.1 1.3 1 1 0 1 1 1 1 Outer membrane usher protein Opacity PF02462.15 AAZ36211.1 - 0.023 14.8 0.2 21 5.2 0.0 3.8 3 1 1 4 4 4 0 Opacity family porin protein Glycohydro_20b2 PF14845.6 AAZ36211.1 - 0.048 14.3 0.1 0.1 13.3 0.1 1.5 1 1 0 1 1 1 0 beta-acetyl hexosaminidase like OMP_b-brl_2 PF13568.6 AAZ36211.1 - 0.062 13.3 0.2 24 4.9 0.1 3.4 2 2 0 2 2 2 0 Outer membrane protein beta-barrel domain TCR PF03638.15 AAZ36211.1 - 0.27 11.6 2.1 0.43 10.9 2.1 1.2 1 0 0 1 1 1 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain MttA_Hcf106 PF02416.16 AAZ36212.1 - 2.7e-13 49.0 0.0 3.5e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 mttA/Hcf106 family T2SSF PF00482.23 AAZ36213.1 - 1.9e-55 186.1 14.5 6.9e-31 106.8 1.0 2.3 2 0 0 2 2 2 2 Type II secretion system (T2SS), protein F Chromate_transp PF02417.15 AAZ36213.1 - 2.7 8.1 12.5 43 4.2 12.5 2.4 1 1 0 1 1 1 0 Chromate transporter Glycos_transf_2 PF00535.26 AAZ36214.1 - 3.7e-26 91.9 0.0 5.8e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAZ36214.1 - 9.6e-22 78.0 0.0 1.3e-21 77.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 AAZ36214.1 - 9.4e-08 31.8 0.0 1.4e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 AAZ36214.1 - 0.00019 21.4 0.0 0.00035 20.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_4 PF13704.6 AAZ36214.1 - 0.00043 20.8 0.1 0.0012 19.3 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 PmbA_TldD PF01523.16 AAZ36215.1 - 1.1e-68 232.1 0.5 1.6e-68 231.6 0.5 1.3 1 0 0 1 1 1 1 Putative modulator of DNA gyrase Methyltrans_SAM PF10672.9 AAZ36216.1 - 2.7e-17 62.8 0.0 4e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase PUA_3 PF17785.1 AAZ36216.1 - 2.8e-13 49.5 0.0 6.3e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 PUA-like domain Cons_hypoth95 PF03602.15 AAZ36216.1 - 2.8e-12 46.6 0.0 4.6e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.6 AAZ36216.1 - 2.2e-09 37.3 0.0 9e-09 35.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.10 AAZ36216.1 - 6e-09 35.7 0.0 9e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.14 AAZ36216.1 - 7e-09 35.4 0.0 1.4e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 AAZ36216.1 - 1.2e-08 34.9 0.0 1.7e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 AAZ36216.1 - 4.7e-06 27.2 0.3 0.00011 22.9 0.1 2.8 2 1 1 3 3 3 1 Methyltransferase domain UPF0020 PF01170.18 AAZ36216.1 - 0.00012 21.8 0.0 0.00018 21.2 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.13 AAZ36216.1 - 0.00017 21.1 0.0 0.00029 20.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 AAZ36216.1 - 0.00034 21.2 0.2 0.052 14.2 0.1 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 AAZ36216.1 - 0.00065 19.4 0.0 0.016 14.9 0.0 2.7 2 1 0 2 2 2 1 16S rRNA methyltransferase RsmB/F Methyltransf_24 PF13578.6 AAZ36216.1 - 0.0045 18.0 0.0 0.016 16.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain TetR PF13972.6 AAZ36217.1 - 6.9e-33 113.4 0.2 9e-33 113.0 0.2 1.1 1 0 0 1 1 1 1 Bacterial transcriptional repressor TetR_N PF00440.23 AAZ36217.1 - 7.4e-11 41.7 0.0 1.3e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 AAZ36217.1 - 0.012 15.9 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain HTH_24 PF13412.6 AAZ36217.1 - 0.056 13.0 0.0 0.16 11.6 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Flavi_capsid PF01003.19 AAZ36217.1 - 0.07 12.9 0.7 0.44 10.3 0.3 2.0 2 0 0 2 2 2 0 Flavivirus capsid protein C Baculo_PEP_C PF04513.12 AAZ36217.1 - 0.07 13.2 0.3 0.11 12.5 0.3 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus HTH_10 PF04967.12 AAZ36217.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain Put_DNA-bind_N PF06971.13 AAZ36217.1 - 0.11 12.5 0.3 2 8.5 0.0 2.8 2 1 1 3 3 3 0 Putative DNA-binding protein N-terminus OsmC PF02566.19 AAZ36219.1 - 3.5e-21 75.5 0.0 4.7e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 OsmC-like protein MscS_TM PF12794.7 AAZ36220.1 - 2.2e-101 339.1 24.8 5.1e-101 337.9 24.8 1.7 1 0 0 1 1 1 1 Mechanosensitive ion channel inner membrane domain 1 MscS_porin PF12795.7 AAZ36220.1 - 1e-61 208.5 53.7 1e-61 208.5 53.7 2.3 2 0 0 2 2 2 1 Mechanosensitive ion channel porin domain MS_channel PF00924.18 AAZ36220.1 - 1.4e-55 188.1 0.6 4e-55 186.5 0.6 1.9 1 0 0 1 1 1 1 Mechanosensitive ion channel Ferritin PF00210.24 AAZ36221.1 - 7.2e-35 120.0 0.5 8.2e-35 119.8 0.5 1.0 1 0 0 1 1 1 1 Ferritin-like domain PDDEXK_3 PF13366.6 AAZ36222.1 - 0.0028 18.0 0.0 0.0049 17.2 0.0 1.5 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily NMT1 PF09084.11 AAZ36223.1 - 5.5e-21 75.5 0.0 8e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 AAZ36223.1 - 7.5e-13 48.8 0.9 7.5e-13 48.8 0.9 1.4 2 0 0 2 2 2 1 NMT1-like family Phosphonate-bd PF12974.7 AAZ36223.1 - 3.5e-11 43.2 1.0 5e-11 42.7 1.0 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 AAZ36223.1 - 5.4e-08 32.5 1.2 1.1e-07 31.6 0.5 1.7 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 NMT1_3 PF16868.5 AAZ36223.1 - 1.6e-06 27.8 0.0 3.5e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 NMT1-like family Lipoprotein_9 PF03180.14 AAZ36223.1 - 0.05 12.7 0.0 0.45 9.6 0.0 2.2 1 1 2 3 3 3 0 NLPA lipoprotein APH PF01636.23 AAZ36224.1 - 1.3e-35 123.5 1.3 1.3e-35 123.5 1.3 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 AAZ36224.1 - 0.00024 20.8 0.0 0.00032 20.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF4096 PF13340.6 AAZ36225.1 - 5.8e-25 87.3 0.4 1.5e-24 86.0 0.4 1.8 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1 PF01609.21 AAZ36225.1 - 3.2e-14 53.1 0.0 5.7e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AAZ36225.1 - 7.2e-10 39.1 0.2 2.1e-09 37.6 0.2 1.9 1 0 0 1 1 1 1 Transposase DDE domain HTH_Tnp_Tc3_2 PF01498.18 AAZ36225.1 - 0.061 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Transposase ThiF PF00899.21 AAZ36226.1 - 6.3e-40 137.1 0.1 8.4e-40 136.7 0.1 1.1 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 AAZ36226.1 - 0.00015 22.0 1.2 0.00071 19.8 1.2 2.0 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 AAZ36226.1 - 0.0013 18.7 0.1 0.0018 18.2 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 AAZ36226.1 - 0.12 12.9 6.7 0.13 12.7 3.2 2.4 2 1 0 2 2 2 0 Putative NAD(P)-binding Melittin PF01372.17 AAZ36226.1 - 1.3 9.1 4.4 1.3 9.2 0.8 2.5 2 0 0 2 2 2 0 Melittin Cupin_4 PF08007.12 AAZ36227.1 - 3.1e-106 355.5 0.1 3.6e-106 355.3 0.1 1.0 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_1 PF00190.22 AAZ36227.1 - 0.0009 18.9 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 AAZ36227.1 - 0.0028 17.5 0.1 0.0062 16.5 0.1 1.5 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_8 PF13621.6 AAZ36227.1 - 0.0084 15.8 0.4 0.1 12.3 0.4 2.5 2 1 0 2 2 2 1 Cupin-like domain Cupin_2 PF07883.11 AAZ36227.1 - 0.065 13.0 0.0 0.56 10.0 0.0 2.2 2 0 0 2 2 2 0 Cupin domain Asp_Arg_Hydrox PF05118.15 AAZ36227.1 - 0.08 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Aspartyl/Asparaginyl beta-hydroxylase Ribosomal_L3 PF00297.22 AAZ36228.1 - 3.3e-17 62.5 7.3 6.4e-17 61.6 5.1 2.2 1 1 1 2 2 2 2 Ribosomal protein L3 adh_short PF00106.25 AAZ36229.1 - 3.1e-45 154.1 0.0 4.1e-45 153.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAZ36229.1 - 9.7e-35 120.2 0.0 1.2e-34 119.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 AAZ36229.1 - 3.1e-06 26.6 0.0 4.1e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 AAZ36229.1 - 5e-06 26.1 0.1 9.6e-06 25.2 0.0 1.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 AAZ36229.1 - 5e-06 26.5 0.0 8.1e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 AAZ36229.1 - 0.0077 16.1 0.0 0.017 15.0 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding Ldh_1_N PF00056.23 AAZ36229.1 - 0.0084 16.2 0.1 0.014 15.5 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 AAZ36229.1 - 0.01 14.8 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 AAZ36229.1 - 0.03 13.4 0.0 0.039 13.1 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain TrkA_N PF02254.18 AAZ36229.1 - 0.052 13.8 0.1 0.15 12.3 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain GDP_Man_Dehyd PF16363.5 AAZ36229.1 - 0.054 12.9 0.0 0.065 12.6 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase F420_oxidored PF03807.17 AAZ36229.1 - 0.091 13.4 0.0 0.22 12.1 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 AAZ36229.1 - 0.14 12.1 0.1 0.21 11.5 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AMP-binding PF00501.28 AAZ36230.1 - 6e-97 324.9 0.0 9e-97 324.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 AAZ36230.1 - 4.2e-57 193.8 0.0 3.6e-29 101.7 0.0 2.3 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.25 AAZ36230.1 - 1.8e-28 98.7 0.0 9.4e-08 32.3 0.0 3.8 3 0 0 3 3 3 3 Phosphopantetheine attachment site Methyltransf_12 PF08242.12 AAZ36230.1 - 9.5e-08 32.7 0.0 2.8e-07 31.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain AMP-binding_C PF13193.6 AAZ36230.1 - 3.3e-06 28.0 0.0 0.001 20.0 0.0 2.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Methyltransf_23 PF13489.6 AAZ36230.1 - 0.0014 18.5 2.4 0.0084 16.0 0.0 3.1 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAZ36230.1 - 0.0064 17.2 0.0 0.025 15.3 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAZ36230.1 - 0.024 14.4 0.0 0.064 13.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 AAZ36230.1 - 0.038 14.6 0.0 0.12 13.1 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain CN_hydrolase PF00795.22 AAZ36231.1 - 1.3e-33 116.4 0.0 1.5e-33 116.2 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase ALGX PF16822.5 AAZ36232.1 - 6e-98 327.8 0.3 7.4e-98 327.5 0.3 1.1 1 0 0 1 1 1 1 SGNH hydrolase-like domain, acetyltransferase AlgX DHHW PF14286.6 AAZ36232.1 - 7.7e-05 22.2 0.0 0.025 13.9 0.0 2.1 1 1 0 2 2 2 2 DHHW protein DUF1704 PF08014.11 AAZ36233.1 - 2.4e-133 444.7 0.0 2.8e-133 444.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1704) Peptidase_M48 PF01435.18 AAZ36234.1 - 2.3e-31 109.1 0.2 3.8e-31 108.4 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M48 TPR_19 PF14559.6 AAZ36234.1 - 7.4e-21 74.4 2.8 9.4e-10 38.9 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 AAZ36234.1 - 6e-09 36.0 12.6 0.00063 20.3 0.0 5.6 3 1 3 6 6 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 AAZ36234.1 - 2.7e-05 24.5 3.4 0.059 14.0 0.0 4.4 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 AAZ36234.1 - 5.3e-05 23.8 11.7 0.0011 19.6 0.0 4.3 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 AAZ36234.1 - 0.0003 20.4 0.1 0.1 12.3 0.0 2.9 3 0 0 3 3 3 1 TPR repeat TPR_17 PF13431.6 AAZ36234.1 - 0.00045 20.4 0.0 7.4 7.2 0.0 4.5 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 AAZ36234.1 - 0.0007 19.5 2.8 2.3 8.6 0.0 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_20 PF14561.6 AAZ36234.1 - 0.00082 19.7 0.3 0.076 13.4 0.1 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 AAZ36234.1 - 0.0027 17.8 7.9 0.24 11.6 0.2 4.7 3 1 1 4 4 4 1 Tetratricopeptide repeat YfiO PF13525.6 AAZ36234.1 - 0.0082 15.9 0.0 0.047 13.4 0.0 2.1 1 1 1 2 2 2 1 Outer membrane lipoprotein Fis1_TPR_C PF14853.6 AAZ36234.1 - 0.0095 16.0 0.1 0.1 12.7 0.0 2.5 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat NARP1 PF12569.8 AAZ36234.1 - 0.058 12.3 0.1 1.8 7.3 0.0 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 TPR_8 PF13181.6 AAZ36234.1 - 0.099 12.9 0.1 6.4 7.3 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 AAZ36234.1 - 0.13 12.5 0.2 14 6.0 0.0 3.2 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 AAZ36234.1 - 0.31 10.9 1.6 30 4.7 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.9 AAZ36234.1 - 1.7 8.3 6.0 0.23 11.2 0.1 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat-like domain MFS_1 PF07690.16 AAZ36235.1 - 5.7e-17 61.7 49.4 8.7e-09 34.8 17.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Acatn PF13000.7 AAZ36235.1 - 0.12 10.9 9.9 0.17 10.3 5.8 2.5 1 1 1 2 2 2 0 Acetyl-coenzyme A transporter 1 Beta_elim_lyase PF01212.21 AAZ36236.1 - 5.5e-92 308.2 0.0 7.2e-92 307.8 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 AAZ36236.1 - 7.9e-11 41.7 0.0 1e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 AAZ36236.1 - 0.00015 21.2 0.0 0.0013 18.2 0.0 2.0 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 AAZ36236.1 - 0.0049 15.5 0.0 0.0091 14.6 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme ATPgrasp_Ter PF15632.6 AAZ36237.1 - 8.2e-42 142.1 0.0 1.4e-41 141.3 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATPgrasp_ST PF14397.6 AAZ36237.1 - 7e-05 22.2 0.0 0.041 13.1 0.0 2.1 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 AAZ36237.1 - 0.00062 19.9 0.0 0.017 15.1 0.0 2.7 2 1 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.17 AAZ36237.1 - 0.049 13.1 0.0 0.78 9.2 0.0 2.1 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain DUF1315 PF07023.12 AAZ36238.1 - 4.5e-26 90.8 0.1 5.1e-26 90.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1315) LysE PF01810.18 AAZ36239.1 - 2.3e-18 66.4 17.6 3.2e-18 65.9 17.6 1.2 1 0 0 1 1 1 1 LysE type translocator Herpes_BLRF2 PF05812.12 AAZ36240.1 - 0.00037 20.6 0.0 0.00065 19.8 0.0 1.4 1 0 0 1 1 1 1 Herpesvirus BLRF2 protein Takusan PF04822.13 AAZ36240.1 - 0.00079 19.3 0.9 0.0012 18.7 0.9 1.2 1 0 0 1 1 1 1 Takusan HrpJ PF07201.11 AAZ36240.1 - 0.0051 17.1 2.3 0.0062 16.9 2.3 1.1 1 0 0 1 1 1 1 HrpJ-like domain Myosin_tail_1 PF01576.19 AAZ36240.1 - 0.0064 14.4 2.1 0.0078 14.1 2.1 1.0 1 0 0 1 1 1 1 Myosin tail UPF0242 PF06785.11 AAZ36240.1 - 0.0099 16.0 1.6 0.0099 16.0 1.6 1.6 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus aGPT-Pplase1 PF18723.1 AAZ36241.1 - 3.1e-83 279.5 1.7 3.6e-83 279.2 1.7 1.0 1 0 0 1 1 1 1 alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 1 GTP_EFTU PF00009.27 AAZ36242.1 - 5.5e-56 189.2 0.0 8.8e-56 188.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 AAZ36242.1 - 2.8e-21 75.3 0.0 5.9e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 AAZ36242.1 - 9.9e-10 38.7 0.6 3.1e-09 37.1 0.3 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 AAZ36242.1 - 8.3e-07 29.1 0.1 1.6e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 AAZ36242.1 - 0.00042 19.7 0.1 0.00068 19.0 0.1 1.2 1 0 0 1 1 1 1 Septin EFG_II PF14492.6 AAZ36242.1 - 0.0026 17.8 0.1 0.0058 16.7 0.1 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II AIG1 PF04548.16 AAZ36242.1 - 0.005 16.2 0.1 0.1 11.9 0.0 2.1 1 1 1 2 2 2 1 AIG1 family FeoB_N PF02421.18 AAZ36242.1 - 0.011 15.2 0.0 0.43 10.1 0.0 3.2 3 1 0 3 3 3 0 Ferrous iron transport protein B Dynamin_N PF00350.23 AAZ36242.1 - 0.069 13.2 0.0 0.76 9.8 0.0 2.0 1 1 1 2 2 2 0 Dynamin family Aldolase_II PF00596.21 AAZ36243.1 - 9.1e-36 123.5 0.0 1.1e-35 123.3 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain ArfA PF03889.13 AAZ36244.1 - 1.1e-09 37.7 0.1 1.3e-09 37.4 0.1 1.1 1 0 0 1 1 1 1 Alternative ribosome-rescue factor A Condensation PF00668.20 AAZ36245.1 - 9.8e-228 756.3 13.4 9.7e-115 383.8 2.6 2.1 2 0 0 2 2 2 2 Condensation domain AMP-binding PF00501.28 AAZ36245.1 - 1.9e-199 662.6 0.0 4.1e-100 335.3 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme PP-binding PF00550.25 AAZ36245.1 - 9.4e-34 115.6 3.3 5.5e-16 58.7 0.5 4.8 5 0 0 5 5 5 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 AAZ36245.1 - 5.5e-28 97.8 0.1 3.9e-13 50.2 0.1 3.0 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain CopG_antitoxin PF12441.8 AAZ36245.1 - 0.043 14.4 3.6 0.96 10.0 0.0 3.5 4 0 0 4 4 4 0 CopG antitoxin of type II toxin-antitoxin system GSHPx PF00255.19 AAZ36246.1 - 2.5e-39 133.2 0.0 3.1e-39 132.9 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 AAZ36246.1 - 0.0016 18.3 0.0 0.0023 17.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family BPD_transp_1 PF00528.22 AAZ36247.1 - 2.5e-15 56.7 30.2 3.9e-14 52.8 23.9 3.4 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF4307 PF14155.6 AAZ36247.1 - 0.71 9.7 0.1 0.71 9.7 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4307) T_cell_tran_alt PF15128.6 AAZ36247.1 - 0.77 9.6 3.4 18 5.2 0.1 3.2 2 1 1 3 3 3 0 T-cell leukemia translocation-altered Trans_reg_C PF00486.28 AAZ36248.1 - 1.4e-26 92.4 0.0 2.8e-26 91.4 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Response_reg PF00072.24 AAZ36248.1 - 5.4e-24 84.5 0.1 7.7e-24 84.0 0.1 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Pyr_redox_2 PF07992.14 AAZ36249.1 - 1.3e-52 178.9 1.9 1.5e-52 178.7 1.9 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAZ36249.1 - 1.2e-22 80.6 0.1 4.8e-19 68.7 0.0 2.0 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAZ36249.1 - 2.6e-16 60.0 4.0 1.1e-15 57.9 1.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AAZ36249.1 - 1.3e-05 24.5 6.3 0.0026 16.9 0.1 3.6 4 0 0 4 4 4 2 Glucose inhibited division protein A HI0933_like PF03486.14 AAZ36249.1 - 1.6e-05 23.8 1.2 0.04 12.6 0.1 3.7 3 1 1 4 4 4 2 HI0933-like protein FAD_binding_2 PF00890.24 AAZ36249.1 - 1.7e-05 24.1 10.8 0.00071 18.8 0.3 3.9 1 1 3 5 5 5 2 FAD binding domain FAD_oxidored PF12831.7 AAZ36249.1 - 2.6e-05 23.7 1.7 0.00022 20.7 0.0 2.6 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 AAZ36249.1 - 0.00021 21.7 0.0 0.0067 16.8 0.1 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.17 AAZ36249.1 - 0.00035 19.9 0.1 0.016 14.5 0.1 2.3 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 AAZ36249.1 - 0.0014 18.8 0.1 0.0053 17.0 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 AAZ36249.1 - 0.0051 16.0 0.0 0.048 12.8 0.0 2.3 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 AAZ36249.1 - 0.0081 15.8 4.4 5.7 6.4 0.4 3.6 3 2 0 4 4 4 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 AAZ36249.1 - 0.011 15.0 0.4 0.38 10.0 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain VanW PF04294.13 AAZ36249.1 - 0.071 12.8 0.1 0.18 11.5 0.0 1.7 2 0 0 2 2 2 0 VanW like protein Trp_halogenase PF04820.14 AAZ36249.1 - 0.12 11.1 1.1 2.8 6.7 0.2 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Shikimate_DH PF01488.20 AAZ36249.1 - 0.15 12.2 0.8 2.9 7.9 0.1 2.9 4 0 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 AAZ36249.1 - 0.25 10.5 3.3 3.1 6.9 0.3 2.9 2 2 2 4 4 4 0 FAD binding domain Penicil_amidase PF01804.18 AAZ36250.1 - 7e-197 656.5 6.6 9e-197 656.1 6.6 1.1 1 0 0 1 1 1 1 Penicillin amidase Semialdhyde_dhC PF02774.18 AAZ36251.1 - 7.3e-40 137.0 0.0 9.7e-40 136.6 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 AAZ36251.1 - 1.5e-24 86.7 0.1 2.7e-24 85.9 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 AAZ36251.1 - 0.0081 15.7 0.2 0.014 15.0 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family Gp_dh_C PF02800.20 AAZ36251.1 - 0.023 14.3 1.5 1.3 8.6 0.0 2.4 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DapB_N PF01113.20 AAZ36251.1 - 0.032 14.3 0.0 0.071 13.2 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus UPF0102 PF02021.17 AAZ36252.1 - 1.4e-26 92.5 0.0 1.7e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0102 DUF234 PF03008.14 AAZ36252.1 - 0.02 15.3 0.0 0.048 14.1 0.0 1.5 1 1 1 2 2 2 0 Archaea bacterial proteins of unknown function NERD PF08378.11 AAZ36252.1 - 0.02 15.3 0.0 0.023 15.1 0.0 1.2 1 0 0 1 1 1 0 Nuclease-related domain Pyr_redox_2 PF07992.14 AAZ36253.1 - 6.6e-57 193.0 0.1 9.5e-57 192.5 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAZ36253.1 - 2.4e-20 72.9 0.8 4.6e-17 62.4 0.3 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Rubredoxin_C PF18267.1 AAZ36253.1 - 4e-17 61.9 0.1 1.3e-16 60.2 0.1 1.9 2 0 0 2 2 2 1 Rubredoxin NAD+ reductase C-terminal domain Pyr_redox_3 PF13738.6 AAZ36253.1 - 4.1e-08 32.8 0.0 7.9e-08 31.9 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AAZ36253.1 - 3.4e-06 26.9 4.2 0.26 10.8 1.3 3.4 2 1 1 3 3 3 3 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 AAZ36253.1 - 1.3e-05 25.5 0.0 0.00039 20.8 0.0 2.2 2 0 0 2 2 2 1 Putative NAD(P)-binding HI0933_like PF03486.14 AAZ36253.1 - 7.8e-05 21.5 0.3 0.26 10.0 0.3 3.1 2 1 1 3 3 3 2 HI0933-like protein NAD_binding_9 PF13454.6 AAZ36253.1 - 0.00019 21.4 1.2 0.73 9.8 0.0 4.0 4 0 0 4 4 4 1 FAD-NAD(P)-binding GIDA PF01134.22 AAZ36253.1 - 0.0015 17.7 2.1 0.047 12.8 0.5 3.3 3 1 1 4 4 4 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 AAZ36253.1 - 0.0015 17.8 0.2 0.0084 15.4 0.2 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 AAZ36253.1 - 0.0059 16.8 0.5 0.1 12.9 0.4 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 AAZ36253.1 - 0.016 14.0 1.9 0.18 10.6 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.18 AAZ36253.1 - 0.021 14.7 0.2 0.032 14.1 0.2 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 AAZ36253.1 - 0.022 13.9 1.7 0.044 12.9 0.9 1.9 1 1 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.19 AAZ36253.1 - 0.027 13.7 3.0 0.048 12.9 1.8 1.7 1 1 1 2 2 2 0 FAD binding domain Amino_oxidase PF01593.24 AAZ36253.1 - 0.042 13.1 0.0 4.2 6.5 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 AAZ36253.1 - 0.072 12.1 0.3 6.7 5.7 0.4 2.7 2 1 1 3 3 3 0 Lycopene cyclase protein K_oxygenase PF13434.6 AAZ36253.1 - 0.1 11.7 0.1 0.28 10.3 0.0 1.7 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 AAZ36253.1 - 0.14 12.2 0.8 4.7 7.3 0.2 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase MCPsignal PF00015.21 AAZ36256.1 - 2.2e-39 135.0 37.9 2.7e-38 131.5 24.5 2.8 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AAZ36256.1 - 0.00091 19.6 7.6 0.0021 18.4 0.1 4.4 3 1 0 3 3 3 1 HAMP domain DUF948 PF06103.11 AAZ36256.1 - 0.0021 18.2 29.0 0.62 10.4 1.2 5.9 2 2 2 4 4 4 2 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 AAZ36256.1 - 0.019 15.0 1.0 0.019 15.0 1.0 5.1 3 2 2 6 6 5 0 Laminin Domain II BLOC1_2 PF10046.9 AAZ36256.1 - 0.27 11.6 10.5 6.8 7.1 0.2 4.4 2 2 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_I PF06008.14 AAZ36256.1 - 0.52 10.0 25.5 0.79 9.4 3.3 3.3 3 0 0 3 3 3 0 Laminin Domain I DUF4795 PF16043.5 AAZ36256.1 - 0.63 9.6 11.2 0.81 9.3 0.1 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4795) TMPIT PF07851.13 AAZ36256.1 - 0.8 8.9 5.6 8.7 5.5 3.4 2.7 2 0 0 2 2 2 0 TMPIT-like protein KxDL PF10241.9 AAZ36256.1 - 1.2 9.5 6.7 25 5.3 5.8 2.9 2 0 0 2 2 2 0 Uncharacterized conserved protein CENP-F_leu_zip PF10473.9 AAZ36256.1 - 1.6 8.8 7.7 62 3.6 0.1 3.5 3 1 1 4 4 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Lebercilin PF15619.6 AAZ36256.1 - 1.8 8.2 8.9 0.29 10.8 4.1 2.2 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease LXG PF04740.12 AAZ36256.1 - 2.1 8.0 17.9 0.77 9.4 0.3 4.3 3 1 1 4 4 4 0 LXG domain of WXG superfamily V_ATPase_I PF01496.19 AAZ36256.1 - 2.2 6.1 5.6 3.7 5.3 5.6 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.12 AAZ36256.1 - 2.8 8.0 19.8 2.4 8.2 0.5 5.0 4 2 2 6 6 5 0 Protein of unknown function (DUF1664) DUF2721 PF11026.8 AAZ36256.1 - 3.5 7.5 8.2 3.8 7.4 0.1 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2721) Vps53_N PF04100.12 AAZ36256.1 - 4 6.3 9.6 0.24 10.3 1.0 2.4 2 0 0 2 2 2 0 Vps53-like, N-terminal DASH_Duo1 PF08651.10 AAZ36256.1 - 4.1 7.2 8.5 7.7 6.4 0.4 4.5 5 0 0 5 5 5 0 DASH complex subunit Duo1 PRKG1_interact PF15898.5 AAZ36256.1 - 4.7 8.2 12.8 0.31 12.0 4.6 3.0 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain DHR10 PF18595.1 AAZ36256.1 - 4.9 7.2 21.1 0.3 11.1 7.8 3.7 1 1 1 3 3 3 0 Designed helical repeat protein 10 domain COG2 PF06148.11 AAZ36256.1 - 5.3 7.1 15.1 1.8 8.7 0.3 4.1 3 1 2 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 LacI PF00356.21 AAZ36257.1 - 7.1e-05 22.5 0.1 0.00021 21.0 0.0 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family TetR_N PF00440.23 AAZ36257.1 - 0.00033 20.4 0.0 0.00068 19.4 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_6 PF01418.17 AAZ36257.1 - 0.00034 20.5 0.0 0.00081 19.3 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain, rpiR family HTH_IclR PF09339.10 AAZ36257.1 - 0.011 15.6 0.0 0.03 14.1 0.0 1.8 1 1 0 1 1 1 0 IclR helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 AAZ36257.1 - 0.015 14.7 0.0 0.033 13.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 TetR_C_29 PF17938.1 AAZ36257.1 - 0.026 14.6 0.1 0.079 13.1 0.1 1.8 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain HTH_23 PF13384.6 AAZ36257.1 - 0.045 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_29 PF13551.6 AAZ36257.1 - 0.069 13.2 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn helix Clp_N PF02861.20 AAZ36257.1 - 0.077 13.1 0.1 0.2 11.8 0.1 1.7 1 0 0 1 1 1 0 Clp amino terminal domain, pathogenicity island component HTH_3 PF01381.22 AAZ36257.1 - 0.09 12.8 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix HTH_Tnp_1_2 PF13022.6 AAZ36257.1 - 0.093 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase DUF134 PF02001.16 AAZ36257.1 - 0.12 13.0 0.0 0.28 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF134 SDF PF00375.18 AAZ36258.1 - 3.2e-119 398.4 39.9 3.6e-119 398.3 39.9 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family HAD PF12710.7 AAZ36259.1 - 9.3e-24 84.9 0.0 1.1e-23 84.6 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase AAA_22 PF13401.6 AAZ36260.1 - 2.7e-05 24.5 0.0 4.4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAZ36260.1 - 0.0014 19.0 0.6 0.0043 17.4 0.5 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 AAZ36260.1 - 0.0026 17.5 0.0 0.0036 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AAZ36260.1 - 0.004 17.7 0.0 0.0082 16.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 AAZ36260.1 - 0.0086 16.1 0.1 2.2 8.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) KTI12 PF08433.10 AAZ36260.1 - 0.01 15.3 0.0 0.016 14.7 0.0 1.4 1 1 0 1 1 1 0 Chromatin associated protein KTI12 Thymidylate_kin PF02223.17 AAZ36260.1 - 0.027 14.2 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 Thymidylate kinase ATP_bind_1 PF03029.17 AAZ36260.1 - 0.033 14.0 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein PRK PF00485.18 AAZ36260.1 - 0.04 13.7 0.0 0.059 13.1 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family ABC_tran PF00005.27 AAZ36260.1 - 0.042 14.4 0.0 0.091 13.3 0.0 1.7 1 1 0 1 1 1 0 ABC transporter APS_kinase PF01583.20 AAZ36260.1 - 0.046 13.6 0.3 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 Adenylylsulphate kinase MobB PF03205.14 AAZ36260.1 - 0.046 13.6 0.0 0.083 12.8 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.17 AAZ36260.1 - 0.051 13.7 0.0 0.1 12.7 0.0 1.6 2 0 0 2 2 2 0 Helicase HerA, central domain GGDEF PF00990.21 AAZ36261.1 - 1.4e-42 145.2 0.1 5e-42 143.4 0.1 2.0 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain CHASE PF03924.13 AAZ36261.1 - 1.7e-35 122.6 0.2 3e-35 121.9 0.2 1.4 1 0 0 1 1 1 1 CHASE domain PAS PF00989.25 AAZ36261.1 - 1.4e-14 54.1 0.0 5.2e-09 36.1 0.0 3.4 2 1 0 2 2 2 2 PAS fold PAS_9 PF13426.7 AAZ36261.1 - 1.2e-12 48.0 0.0 1e-09 38.6 0.0 3.0 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.12 AAZ36261.1 - 2.2e-12 47.1 0.0 1.4e-07 31.7 0.0 3.5 2 1 0 2 2 2 2 PAS fold PAS_4 PF08448.10 AAZ36261.1 - 4.8e-10 39.7 6.6 0.0003 21.0 0.1 4.0 4 1 0 4 4 4 2 PAS fold PAS_8 PF13188.7 AAZ36261.1 - 5e-05 23.2 0.0 0.0067 16.4 0.0 2.9 2 0 0 2 2 2 1 PAS domain DUF4381 PF14316.6 AAZ36261.1 - 3.4 7.9 6.4 28 4.9 1.9 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Ribosomal_L31 PF01197.18 AAZ36262.1 - 1.8e-09 37.6 0.1 2.2e-09 37.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L31 Phytase-like PF13449.6 AAZ36263.1 - 3.8e-10 40.2 0.0 1.8e-09 37.9 0.0 1.9 1 1 0 1 1 1 1 Esterase-like activity of phytase SdiA-regulated PF06977.11 AAZ36263.1 - 2.5e-05 23.6 0.0 0.03 13.6 0.0 2.5 3 0 0 3 3 3 2 SdiA-regulated Gag_spuma PF03276.14 AAZ36263.1 - 0.14 10.5 0.0 0.19 10.2 0.0 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Waikav_capsid_1 PF12264.8 AAZ36263.1 - 0.17 11.4 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Waikavirus capsid protein 1 Glyco_trans_2_3 PF13632.6 AAZ36264.1 - 4.6e-47 160.5 1.3 4.6e-47 160.5 1.3 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 AAZ36264.1 - 3.2e-32 112.3 0.5 5.5e-32 111.5 0.5 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 T2SSE_N PF05157.15 AAZ36264.1 - 3.8e-12 46.5 1.7 4.3e-10 39.8 0.6 2.8 2 0 0 2 2 2 1 Type II secretion system (T2SS), protein E, N-terminal domain DUF1654 PF07867.11 AAZ36264.1 - 0.075 12.8 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) Cpn60_TCP1 PF00118.24 AAZ36265.1 - 8.8e-95 318.2 15.9 1.4e-94 317.5 15.9 1.3 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1730 PF08331.10 AAZ36266.1 - 1.5e-23 82.5 0.0 3.1e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1730) Fer4_16 PF13484.6 AAZ36266.1 - 2.5e-20 73.2 2.5 4.1e-20 72.5 2.5 1.4 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 AAZ36266.1 - 2.4e-06 28.0 4.5 5.3e-06 26.9 4.5 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAZ36266.1 - 1.5e-05 25.0 3.8 0.04 14.0 1.2 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAZ36266.1 - 0.00016 21.8 0.7 0.041 14.1 0.1 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 AAZ36266.1 - 0.0018 18.3 8.3 0.58 10.3 0.2 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 AAZ36266.1 - 0.0023 18.0 6.1 0.84 9.8 2.0 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 AAZ36266.1 - 0.02 14.7 11.5 0.029 14.2 2.4 2.7 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_2 PF12797.7 AAZ36266.1 - 0.05 13.7 12.8 0.4 10.9 4.9 3.1 3 0 0 3 3 3 0 4Fe-4S binding domain Condensin2nSMC PF12422.8 AAZ36266.1 - 0.087 13.0 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit Fer4_4 PF12800.7 AAZ36266.1 - 0.2 12.2 7.6 7.9 7.3 2.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_8 PF13183.6 AAZ36266.1 - 0.49 10.9 10.1 8.2 7.0 10.2 2.3 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 AAZ36266.1 - 1 10.4 9.7 7.3 7.8 3.2 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_18 PF13746.6 AAZ36266.1 - 1.4 9.1 3.7 7.2 6.9 0.9 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain Epimerase PF01370.21 AAZ36267.1 - 4.3e-13 49.3 0.0 8.5e-13 48.3 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 AAZ36267.1 - 2.3e-11 44.0 0.2 3.5e-11 43.3 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 AAZ36267.1 - 7.1e-07 28.6 0.3 1.8e-06 27.3 0.1 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain NmrA PF05368.13 AAZ36267.1 - 2.9e-06 27.0 0.2 1.1e-05 25.2 0.2 1.9 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 AAZ36267.1 - 0.025 14.0 0.0 0.065 12.7 0.0 1.7 1 1 0 1 1 1 0 short chain dehydrogenase THF_DHG_CYH_C PF02882.19 AAZ36267.1 - 0.026 13.9 0.0 0.045 13.1 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3Beta_HSD PF01073.19 AAZ36267.1 - 0.048 12.7 0.0 0.11 11.5 0.0 1.6 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 AAZ36267.1 - 0.074 13.5 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain EAL PF00563.20 AAZ36268.1 - 9.3e-74 247.9 0.0 1.5e-73 247.3 0.0 1.3 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AAZ36268.1 - 2.3e-37 128.2 0.4 4.2e-37 127.4 0.4 1.5 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain FtsL PF04999.13 AAZ36268.1 - 0.1 12.6 0.1 0.29 11.2 0.1 1.8 1 0 0 1 1 1 0 Cell division protein FtsL SoxD PF04267.12 AAZ36269.1 - 1.8e-26 92.1 0.1 2.1e-26 91.9 0.1 1.1 1 0 0 1 1 1 1 Sarcosine oxidase, delta subunit family DUF3085 PF11284.8 AAZ36269.1 - 0.1 12.9 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3085) ABC_tran PF00005.27 AAZ36270.1 - 1.2e-31 110.0 0.0 2e-31 109.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter TOBE_2 PF08402.10 AAZ36270.1 - 9.3e-16 57.8 0.0 2.4e-15 56.5 0.0 1.7 1 0 0 1 1 1 1 TOBE domain AAA_21 PF13304.6 AAZ36270.1 - 7e-09 35.9 0.2 0.00098 19.0 0.1 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system OB_MalK PF17912.1 AAZ36270.1 - 1.8e-08 35.1 0.0 6.5e-08 33.3 0.0 2.1 1 0 0 1 1 1 1 MalK OB fold domain TOBE PF03459.17 AAZ36270.1 - 2e-05 24.8 0.0 5.1e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 TOBE domain RsgA_GTPase PF03193.16 AAZ36270.1 - 0.00031 20.7 0.2 0.001 19.0 0.1 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 AAZ36270.1 - 0.0012 19.3 0.2 0.0024 18.3 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 AAZ36270.1 - 0.0018 17.8 0.0 0.89 8.9 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 AAZ36270.1 - 0.0061 16.3 0.0 0.044 13.5 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 AAZ36270.1 - 0.0065 16.2 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AAZ36270.1 - 0.0071 16.9 0.1 0.014 16.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 AAZ36270.1 - 0.0081 16.6 0.0 0.16 12.4 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 AAZ36270.1 - 0.013 15.4 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain CysA_C_terminal PF17850.1 AAZ36270.1 - 0.014 15.9 0.0 0.038 14.6 0.0 1.7 1 0 0 1 1 1 0 CysA C-terminal regulatory domain AAA_33 PF13671.6 AAZ36270.1 - 0.017 15.3 0.0 0.046 13.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 AAZ36270.1 - 0.021 14.4 0.0 0.073 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 AAZ36270.1 - 0.021 15.1 0.6 0.08 13.2 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 AAZ36270.1 - 0.052 13.8 0.1 0.15 12.3 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AAZ36270.1 - 0.07 13.7 0.0 0.12 12.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 AAZ36270.1 - 0.093 12.8 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.14 AAZ36270.1 - 0.11 12.5 0.1 0.33 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 AAZ36270.1 - 0.19 12.1 0.0 0.38 11.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase HemolysinCabind PF00353.19 AAZ36271.1 - 8.8e-28 95.9 80.0 6.4e-10 38.8 14.0 7.9 5 3 2 8 8 8 6 RTX calcium-binding nonapeptide repeat (4 copies) Peptidase_M10_C PF08548.11 AAZ36271.1 - 3.1e-14 53.3 11.2 4.8e-08 33.1 0.4 3.5 3 0 0 3 3 3 3 Peptidase M10 serralysin C terminal EAL PF00563.20 AAZ36272.1 - 2.2e-73 246.7 1.1 4.6e-73 245.6 0.2 1.8 2 0 0 2 2 2 1 EAL domain GGDEF PF00990.21 AAZ36272.1 - 9.5e-32 110.0 0.0 1.6e-31 109.2 0.0 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain ATP-synt_B PF00430.18 AAZ36273.1 - 1.9e-36 125.0 11.4 2.6e-36 124.6 11.4 1.2 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) Apolipoprotein PF01442.18 AAZ36273.1 - 0.00038 20.4 10.0 0.00057 19.8 10.0 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Mt_ATP-synt_B PF05405.14 AAZ36273.1 - 0.0053 16.4 4.4 0.032 13.9 4.4 2.0 1 1 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) V_ATPase_I PF01496.19 AAZ36273.1 - 0.028 12.3 0.1 0.032 12.1 0.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family V-ATPase_G_2 PF16999.5 AAZ36273.1 - 0.056 13.9 23.0 0.2 12.1 22.8 2.0 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit V-ATPase_G PF03179.15 AAZ36273.1 - 0.059 13.9 18.9 0.035 14.7 15.1 1.8 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit CdvA PF18822.1 AAZ36273.1 - 0.091 12.6 7.1 0.63 9.9 4.5 2.6 1 1 2 3 3 3 0 CdvA-like coiled-coil domain MASE2 PF05230.11 AAZ36273.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 MASE2 domain DUF883 PF05957.13 AAZ36273.1 - 0.14 12.8 12.6 0.19 12.3 11.1 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF4570 PF15134.6 AAZ36273.1 - 0.29 11.2 4.1 0.44 10.6 4.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) HrpE PF06188.12 AAZ36273.1 - 0.38 10.6 12.6 0.46 10.3 12.6 1.2 1 0 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E DivIVA PF05103.13 AAZ36273.1 - 0.4 10.8 14.9 0.92 9.6 14.6 1.8 1 1 1 2 2 2 0 DivIVA protein DUF724 PF05266.14 AAZ36273.1 - 0.48 10.2 6.1 0.63 9.8 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) YtxH PF12732.7 AAZ36273.1 - 2.2 8.9 11.6 20 5.8 11.6 2.4 1 1 0 1 1 1 0 YtxH-like protein YidC_periplas PF14849.6 AAZ36274.1 - 5.3e-86 289.0 0.8 7e-86 288.6 0.8 1.1 1 0 0 1 1 1 1 YidC periplasmic domain 60KD_IMP PF02096.20 AAZ36274.1 - 2.7e-60 203.1 9.0 4.2e-60 202.4 9.0 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein Ank_2 PF12796.7 AAZ36275.1 - 5.4e-28 97.4 2.0 5.5e-12 46.1 0.0 2.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 AAZ36275.1 - 1e-21 76.7 7.1 2e-08 34.3 0.2 3.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 AAZ36275.1 - 6.7e-19 68.0 0.4 2.3e-07 31.2 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 AAZ36275.1 - 1.3e-13 50.7 0.6 0.0011 19.3 0.1 3.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 AAZ36275.1 - 3.8e-10 39.1 0.9 0.019 15.4 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeat Pribosyltran PF00156.27 AAZ36277.1 - 1.7e-15 56.9 0.0 2e-15 56.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 AAZ36277.1 - 8.2e-05 22.1 0.0 9.5e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 AAZ36277.1 - 0.013 15.0 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase TauD PF02668.16 AAZ36278.1 - 1.5e-55 188.9 0.1 1.8e-55 188.6 0.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.6 AAZ36278.1 - 0.031 15.2 0.0 17 6.4 0.0 2.5 2 1 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily MIP PF00230.20 AAZ36279.1 - 2.9e-63 213.6 10.7 3.5e-63 213.4 10.7 1.0 1 0 0 1 1 1 1 Major intrinsic protein AAA_2 PF07724.14 AAZ36280.1 - 2.1e-43 148.4 0.1 4.6e-42 144.0 0.0 3.1 4 0 0 4 4 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 AAZ36280.1 - 3e-30 104.2 3.7 5.7e-30 103.3 1.2 2.5 2 0 0 2 2 2 1 AAA lid domain AAA PF00004.29 AAZ36280.1 - 3.9e-19 69.4 0.3 1.2e-08 35.5 0.0 3.6 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AAZ36280.1 - 3.2e-14 53.1 0.1 2.3e-10 40.6 0.0 3.5 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) ClpB_D2-small PF10431.9 AAZ36280.1 - 7.9e-13 48.3 1.2 2.6e-12 46.6 1.2 1.8 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.6 AAZ36280.1 - 4e-09 37.1 12.8 6.5e-05 23.4 0.2 5.9 6 1 0 6 6 5 2 AAA ATPase domain Clp_N PF02861.20 AAZ36280.1 - 8.5e-09 35.4 0.8 8.8e-05 22.6 0.1 3.0 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA_22 PF13401.6 AAZ36280.1 - 2.8e-08 34.1 3.3 0.082 13.2 0.1 5.6 3 1 1 4 4 4 2 AAA domain Sigma54_activat PF00158.26 AAZ36280.1 - 4.6e-06 26.5 0.0 0.00051 19.8 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain TniB PF05621.11 AAZ36280.1 - 5.7e-06 25.9 0.8 0.079 12.4 0.0 4.7 5 0 0 5 5 5 1 Bacterial TniB protein ATPase_2 PF01637.18 AAZ36280.1 - 1.8e-05 24.8 0.2 1.2 9.0 0.0 3.7 3 1 1 4 4 4 2 ATPase domain predominantly from Archaea AAA_7 PF12775.7 AAZ36280.1 - 3.7e-05 23.3 0.0 0.079 12.5 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 AAZ36280.1 - 0.00015 21.6 0.1 0.38 10.5 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein NACHT PF05729.12 AAZ36280.1 - 0.00026 21.0 0.1 0.056 13.3 0.0 3.0 2 0 0 2 2 2 1 NACHT domain AAA_14 PF13173.6 AAZ36280.1 - 0.00085 19.4 0.0 0.3 11.1 0.0 3.5 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.6 AAZ36280.1 - 0.00088 19.8 1.5 1.6 9.3 0.0 4.0 3 0 0 3 3 3 1 AAA domain ResIII PF04851.15 AAZ36280.1 - 0.0018 18.3 0.0 3 7.8 0.0 3.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_25 PF13481.6 AAZ36280.1 - 0.0035 17.0 3.3 1.2 8.7 0.0 3.3 4 0 0 4 4 3 2 AAA domain Zeta_toxin PF06414.12 AAZ36280.1 - 0.0037 16.6 0.0 0.053 12.8 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_29 PF13555.6 AAZ36280.1 - 0.0085 15.8 0.0 7.1 6.5 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 AAZ36280.1 - 0.013 15.9 0.0 7.8 6.9 0.0 3.2 3 0 0 3 3 3 0 RNA helicase AAA_24 PF13479.6 AAZ36280.1 - 0.021 14.6 0.3 1.2 8.8 0.0 2.9 2 2 0 2 2 2 0 AAA domain TsaE PF02367.17 AAZ36280.1 - 0.024 14.6 0.0 2.1 8.4 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran_CTD PF16326.5 AAZ36280.1 - 0.024 14.9 8.5 0.026 14.7 5.9 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain RuvB_N PF05496.12 AAZ36280.1 - 0.029 14.1 0.7 0.58 9.9 0.0 3.2 4 0 0 4 4 4 0 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 AAZ36280.1 - 0.032 13.4 0.1 10 5.2 0.0 3.1 3 0 0 3 3 3 0 TIP49 P-loop domain NTPase_1 PF03266.15 AAZ36280.1 - 0.033 14.1 0.2 4.3 7.2 0.1 3.1 2 0 0 2 2 2 0 NTPase Hpr_kinase_C PF07475.12 AAZ36280.1 - 0.034 13.7 0.3 0.33 10.5 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_30 PF13604.6 AAZ36280.1 - 0.042 13.6 7.7 0.073 12.8 0.1 3.5 3 2 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 AAZ36280.1 - 0.042 13.8 0.0 13 5.7 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase SRP54 PF00448.22 AAZ36280.1 - 0.043 13.4 0.2 1.3 8.7 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain CbiA PF01656.23 AAZ36280.1 - 0.05 13.6 1.0 1.1 9.3 0.2 3.2 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain T2SSE PF00437.20 AAZ36280.1 - 0.052 12.6 0.1 4.1 6.4 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_23 PF13476.6 AAZ36280.1 - 0.091 13.3 9.3 2.8 8.4 0.1 3.6 2 2 0 2 2 2 0 AAA domain AAA_19 PF13245.6 AAZ36280.1 - 0.12 12.7 2.0 12 6.2 0.2 3.4 3 1 0 3 3 2 0 AAA domain DUF2075 PF09848.9 AAZ36280.1 - 0.42 9.8 1.6 2.5 7.3 0.1 2.9 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.6 AAZ36280.1 - 9.7 6.4 6.6 7.1 6.9 0.1 3.2 3 0 0 3 3 2 0 AAA domain DUF2388 PF09498.10 AAZ36281.1 - 1.9e-27 95.0 2.1 2.9e-27 94.4 2.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2388) GDH_N PF12466.8 AAZ36281.1 - 0.035 14.3 0.1 0.056 13.7 0.1 1.3 1 0 0 1 1 1 0 Glutamate dehydrogenase N terminal DUF1043 PF06295.12 AAZ36282.1 - 0.0077 16.2 1.3 0.012 15.6 1.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1043) DUF1664 PF07889.12 AAZ36282.1 - 0.021 14.9 1.0 0.026 14.6 1.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) MtlR PF05068.12 AAZ36282.1 - 0.034 14.2 0.4 0.043 13.8 0.4 1.0 1 0 0 1 1 1 0 Mannitol repressor Flagellin_C PF00700.21 AAZ36282.1 - 0.038 14.3 0.4 0.088 13.2 0.4 1.6 1 1 1 2 2 2 0 Bacterial flagellin C-terminal helical region Glu-tRNAGln PF02686.15 AAZ36282.1 - 0.041 14.2 0.1 0.057 13.7 0.1 1.3 1 0 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit WXG100 PF06013.12 AAZ36282.1 - 0.047 13.9 1.2 0.39 11.0 0.2 2.0 1 1 1 2 2 2 0 Proteins of 100 residues with WXG DUF913 PF06025.12 AAZ36282.1 - 0.075 12.0 0.1 0.076 12.0 0.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF2452 PF10504.9 AAZ36282.1 - 0.13 11.7 1.0 0.15 11.5 1.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) PP2C_C PF07830.13 AAZ36282.1 - 0.14 12.7 0.3 0.15 12.6 0.3 1.2 1 0 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain DUF4279 PF14106.6 AAZ36282.1 - 0.14 12.3 0.2 0.33 11.2 0.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4279) DUF948 PF06103.11 AAZ36282.1 - 0.17 12.2 2.0 0.23 11.8 2.0 1.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) XhlA PF10779.9 AAZ36282.1 - 0.63 10.3 4.4 2.9 8.2 1.3 2.0 2 0 0 2 2 2 0 Haemolysin XhlA ABC_tran PF00005.27 AAZ36283.1 - 1.2e-35 123.0 0.0 1.5e-35 122.7 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAZ36283.1 - 2.7e-16 60.2 0.4 7.3e-08 32.6 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAZ36283.1 - 4.8e-09 36.0 0.0 1.3e-07 31.2 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 AAZ36283.1 - 3.3e-05 22.9 0.1 0.088 11.6 0.0 2.9 2 1 0 2 2 2 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 AAZ36283.1 - 5e-05 23.0 0.1 9.3e-05 22.1 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AAZ36283.1 - 5.4e-05 23.8 0.1 9e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AAZ36283.1 - 0.00013 21.9 0.1 0.00023 21.1 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 AAZ36283.1 - 0.00013 22.4 0.1 0.0002 21.8 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.20 AAZ36283.1 - 0.00093 19.1 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_22 PF13401.6 AAZ36283.1 - 0.0011 19.2 0.0 0.0025 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AAZ36283.1 - 0.0016 18.6 0.0 0.0023 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 AAZ36283.1 - 0.0022 18.0 0.1 0.0035 17.3 0.0 1.4 2 0 0 2 2 1 1 ATPase domain predominantly from Archaea AAA_13 PF13166.6 AAZ36283.1 - 0.003 16.3 0.0 1.3 7.6 0.0 2.0 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 AAZ36283.1 - 0.0037 17.0 0.0 0.0062 16.3 0.0 1.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 AAZ36283.1 - 0.0083 15.9 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 AAZ36283.1 - 0.018 14.6 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 AAZ36283.1 - 0.022 14.7 0.0 0.042 13.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.6 AAZ36283.1 - 0.028 14.5 0.1 0.062 13.3 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_27 PF13514.6 AAZ36283.1 - 0.037 13.6 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 AAZ36283.1 - 0.041 13.1 0.0 0.067 12.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.6 AAZ36283.1 - 0.044 13.5 0.5 0.1 12.3 0.1 1.7 2 0 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.15 AAZ36283.1 - 0.049 12.4 0.1 0.075 11.8 0.1 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_18 PF13238.6 AAZ36283.1 - 0.05 14.1 0.1 0.11 13.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AAZ36283.1 - 0.055 13.0 0.1 0.59 9.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 AAZ36283.1 - 0.057 12.5 0.0 0.082 12.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.6 AAZ36283.1 - 0.094 13.0 0.3 0.29 11.3 0.1 1.9 3 0 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.18 AAZ36283.1 - 0.15 11.4 0.1 0.25 10.7 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 AAZ36283.1 - 0.15 11.3 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA PF00004.29 AAZ36283.1 - 0.16 12.4 0.0 13 6.2 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AAZ36283.1 - 0.18 11.8 0.0 0.51 10.3 0.0 1.7 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 AAZ36283.1 - 0.21 11.5 0.0 0.32 10.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain G-alpha PF00503.20 AAZ36283.1 - 0.29 10.3 0.0 0.43 9.7 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit GGDEF PF00990.21 AAZ36284.1 - 9.7e-49 165.2 0.0 1.7e-48 164.4 0.0 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_9 PF13426.7 AAZ36284.1 - 3.1e-33 114.1 0.0 1.9e-15 57.0 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 AAZ36284.1 - 3e-28 98.1 0.0 3.6e-14 52.7 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 AAZ36284.1 - 2.4e-21 75.8 0.0 1.4e-09 38.1 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 AAZ36284.1 - 1.6e-20 73.3 0.0 2.6e-10 40.5 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 AAZ36284.1 - 6.4e-16 58.0 0.1 4.6e-07 29.7 0.0 2.6 2 0 0 2 2 2 2 PAS domain GGDEF_2 PF17853.1 AAZ36284.1 - 0.0057 16.9 0.8 0.015 15.6 0.1 2.1 2 1 1 3 3 3 1 GGDEF-like domain PAS_12 PF18095.1 AAZ36284.1 - 0.009 15.7 0.0 0.19 11.3 0.0 2.2 2 0 0 2 2 2 1 UPF0242 C-terminal PAS-like domain ABM PF03992.16 AAZ36285.1 - 3.3e-05 23.9 0.1 0.00013 22.0 0.1 1.8 1 1 1 2 2 2 1 Antibiotic biosynthesis monooxygenase MerR-DNA-bind PF09278.11 AAZ36286.1 - 1.6 9.3 6.5 0.17 12.4 0.8 2.3 3 0 0 3 3 3 0 MerR, DNA binding ABC_tran PF00005.27 AAZ36287.1 - 1.2e-33 116.5 0.0 2.1e-33 115.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter OB_MalK PF17912.1 AAZ36287.1 - 3.6e-13 50.1 0.0 1.4e-12 48.3 0.0 2.1 1 0 0 1 1 1 1 MalK OB fold domain TOBE_2 PF08402.10 AAZ36287.1 - 2.2e-10 40.6 0.0 1.2e-09 38.2 0.0 2.1 2 0 0 2 2 2 1 TOBE domain TOBE PF03459.17 AAZ36287.1 - 6.8e-09 35.9 0.0 2.6e-08 34.0 0.0 2.0 2 0 0 2 2 1 1 TOBE domain AAA_21 PF13304.6 AAZ36287.1 - 2.5e-08 34.1 0.0 0.0067 16.3 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 AAZ36287.1 - 6.7e-06 26.1 0.2 4.3e-05 23.5 0.1 2.0 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 AAZ36287.1 - 5.3e-05 22.8 0.1 0.00019 21.0 0.1 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AAZ36287.1 - 0.00085 19.9 0.1 0.0013 19.3 0.1 1.2 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 AAZ36287.1 - 0.00093 19.2 0.0 0.0013 18.7 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 AAZ36287.1 - 0.0011 19.3 0.0 0.0023 18.4 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AAZ36287.1 - 0.0013 18.4 0.1 0.0031 17.2 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AAZ36287.1 - 0.0058 16.9 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 AAZ36287.1 - 0.01 15.5 0.0 0.025 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 AAZ36287.1 - 0.01 15.6 0.0 0.026 14.2 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 AAZ36287.1 - 0.028 14.8 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 AAZ36287.1 - 0.04 13.5 0.1 7.1 6.2 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 AAZ36287.1 - 0.046 14.1 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase MMR_HSR1 PF01926.23 AAZ36287.1 - 0.049 13.7 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase CysA_C_terminal PF17850.1 AAZ36287.1 - 0.05 14.2 0.0 0.13 12.9 0.0 1.7 1 0 0 1 1 1 0 CysA C-terminal regulatory domain Ribosomal_S17 PF00366.20 AAZ36287.1 - 0.058 13.5 0.3 0.11 12.7 0.3 1.3 1 0 0 1 1 1 0 Ribosomal protein S17 AAA_30 PF13604.6 AAZ36287.1 - 0.068 12.9 0.0 0.1 12.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain DUF1611 PF07755.11 AAZ36287.1 - 0.068 12.4 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1611_C) P-loop domain AAA_5 PF07728.14 AAZ36287.1 - 0.069 13.1 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 AAZ36287.1 - 0.069 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 AAZ36287.1 - 0.16 11.9 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.17 AAZ36287.1 - 0.17 11.6 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Lactonase PF10282.9 AAZ36288.1 - 9e-90 301.4 0.0 1.1e-89 301.1 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SGL PF08450.12 AAZ36288.1 - 7.1e-07 29.0 0.0 0.0054 16.4 0.0 3.4 1 1 2 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region PD40 PF07676.12 AAZ36288.1 - 0.00017 21.4 0.7 6 6.9 0.0 4.3 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat WD40 PF00400.32 AAZ36288.1 - 0.00067 20.4 0.1 11 7.1 0.0 4.9 5 1 0 5 5 5 1 WD domain, G-beta repeat SoxE PF06525.11 AAZ36288.1 - 0.12 11.9 0.0 1.9 8.0 0.0 2.6 3 0 0 3 3 3 0 Sulfocyanin (SoxE) domain Coatomer_WDAD PF04053.14 AAZ36288.1 - 0.19 10.7 0.0 4.1 6.3 0.0 2.1 2 0 0 2 2 2 0 Coatomer WD associated region NTP_transf_3 PF12804.7 AAZ36289.1 - 1.8e-30 106.4 0.7 2.2e-30 106.1 0.7 1.0 1 0 0 1 1 1 1 MobA-like NTP transferase domain Sugar_tr PF00083.24 AAZ36290.1 - 5.4e-36 124.4 31.1 9.3e-26 90.7 9.4 2.6 1 1 2 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.16 AAZ36290.1 - 1.3e-23 83.5 60.7 1.1e-12 47.5 33.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 AAZ36290.1 - 0.00086 18.0 29.6 0.042 12.4 18.3 2.4 2 1 0 2 2 2 2 MFS/sugar transport protein GlutR_N PF05201.15 AAZ36291.1 - 1.1e-51 174.4 0.2 2.2e-51 173.4 0.2 1.5 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, N-terminal domain Shikimate_DH PF01488.20 AAZ36291.1 - 2.6e-47 160.3 1.1 3.7e-47 159.9 0.1 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase GlutR_dimer PF00745.20 AAZ36291.1 - 1.4e-21 76.7 1.3 3.4e-21 75.5 1.3 1.7 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, dimerisation domain F420_oxidored PF03807.17 AAZ36291.1 - 0.0024 18.4 0.8 0.01 16.4 0.1 2.5 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 AAZ36291.1 - 0.05 13.9 0.1 0.14 12.4 0.1 1.8 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain LPD23 PF18838.1 AAZ36291.1 - 0.19 11.5 1.2 0.49 10.2 0.2 2.2 2 0 0 2 2 2 0 Large polyvalent protein associated domain 23 OEP PF02321.18 AAZ36292.1 - 1.2e-44 152.4 25.3 1.3e-27 96.9 2.2 2.4 2 0 0 2 2 2 2 Outer membrane efflux protein SIR2 PF02146.17 AAZ36293.1 - 1.4e-44 152.1 0.0 1.7e-44 151.8 0.0 1.1 1 0 0 1 1 1 1 Sir2 family zf-dskA_traR PF01258.17 AAZ36293.1 - 0.024 14.6 0.4 0.13 12.2 0.3 2.3 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger adh_short_C2 PF13561.6 AAZ36294.1 - 2.4e-55 187.7 0.5 2.9e-55 187.4 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAZ36294.1 - 1.3e-41 142.2 0.5 1.6e-41 141.9 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 AAZ36294.1 - 0.00037 20.0 0.2 0.0027 17.2 0.2 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 AAZ36294.1 - 0.00059 19.8 2.7 0.0053 16.7 2.7 2.1 1 1 0 1 1 1 1 KR domain CbiA PF01656.23 AAZ36294.1 - 0.022 14.8 0.0 0.041 13.9 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain 2-Hacid_dh_C PF02826.19 AAZ36294.1 - 0.075 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 AAZ36294.1 - 0.12 11.4 0.0 0.31 10.1 0.0 1.7 1 1 1 2 2 2 0 RmlD substrate binding domain PLDc_N PF13396.6 AAZ36295.1 - 1.4e-08 34.5 3.5 4.2e-08 33.0 3.5 1.8 1 1 0 1 1 1 1 Phospholipase_D-nuclease N-terminal NrsF PF06532.11 AAZ36295.1 - 0.0044 16.8 1.1 0.0048 16.6 1.1 1.0 1 0 0 1 1 1 1 Negative regulator of sigma F DUF2304 PF10066.9 AAZ36295.1 - 0.014 15.6 3.9 0.022 15.0 3.9 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) DUF4293 PF14126.6 AAZ36295.1 - 0.019 15.3 0.1 0.02 15.2 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) DctQ PF04290.12 AAZ36295.1 - 0.024 14.6 1.3 0.028 14.3 1.3 1.1 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF1970 PF09301.10 AAZ36295.1 - 0.082 13.2 0.4 0.094 13.0 0.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1970) JAMP PF05571.12 AAZ36295.1 - 0.12 12.0 0.3 0.14 11.8 0.3 1.0 1 0 0 1 1 1 0 JNK1/MAPK8-associated membrane protein DUF3827 PF12877.7 AAZ36295.1 - 0.46 8.8 3.0 0.51 8.6 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Ribosomal_S21 PF01165.20 AAZ36296.1 - 2.7e-22 78.2 5.5 2.7e-22 78.2 5.5 1.6 1 1 1 2 2 2 1 Ribosomal protein S21 DUF799 PF05643.11 AAZ36297.1 - 1.3e-91 305.2 0.2 1.5e-91 305.0 0.2 1.0 1 0 0 1 1 1 1 Putative bacterial lipoprotein (DUF799) DUF4136 PF13590.6 AAZ36297.1 - 0.00093 19.8 0.0 0.0014 19.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4136) LpoB PF13036.6 AAZ36297.1 - 0.078 12.9 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Peptidoglycan-synthase activator LpoB DUF3470 PF11953.8 AAZ36298.1 - 3.5e-22 78.1 1.8 4.4e-22 77.8 1.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3470) Fer4 PF00037.27 AAZ36298.1 - 6.8e-08 32.0 20.4 2.3e-05 24.0 5.3 3.1 3 0 0 3 3 3 3 4Fe-4S binding domain Fer4_10 PF13237.6 AAZ36298.1 - 4e-07 30.0 8.4 0.00042 20.4 0.2 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 AAZ36298.1 - 1.6e-05 25.0 12.6 0.0062 16.6 0.8 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAZ36298.1 - 1.7e-05 25.6 8.5 0.0059 17.5 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_17 PF13534.6 AAZ36298.1 - 2e-05 25.1 7.3 0.0014 19.1 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 AAZ36298.1 - 5.3e-05 23.7 16.0 0.00028 21.4 16.1 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 AAZ36298.1 - 0.00011 22.2 18.8 0.014 15.5 4.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 AAZ36298.1 - 0.00015 21.7 13.5 0.013 15.6 3.2 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 AAZ36298.1 - 0.00019 21.8 8.9 0.0024 18.3 0.1 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAZ36298.1 - 0.00046 20.3 14.2 0.0025 18.0 14.5 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 AAZ36298.1 - 0.0043 17.4 14.7 0.031 14.8 1.2 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_13 PF13370.6 AAZ36298.1 - 1.9 9.1 20.3 0.43 11.2 5.7 2.5 1 1 1 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 AAZ36298.1 - 2.4 9.3 20.4 0.96 10.5 7.2 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Peptidase_M19 PF01244.21 AAZ36299.1 - 2.1e-93 313.0 0.0 2.5e-93 312.7 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Amidohydro_2 PF04909.14 AAZ36299.1 - 0.04 13.7 0.0 0.14 11.9 0.0 1.9 1 1 0 1 1 1 0 Amidohydrolase Tape_meas_lam_C PF09718.10 AAZ36300.1 - 2.1e-06 27.8 1.6 2.1e-06 27.8 1.6 2.4 2 0 0 2 2 2 1 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Myb_CC_LHEQLE PF14379.6 AAZ36300.1 - 0.0078 15.9 0.7 0.0078 15.9 0.7 3.3 3 0 0 3 3 3 1 MYB-CC type transfactor, LHEQLE motif FUSC PF04632.12 AAZ36300.1 - 2.5 6.5 14.0 3.5 6.0 14.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family CENP-K PF11802.8 AAZ36300.1 - 6.1 6.3 11.8 5.1 6.6 10.5 1.4 1 1 0 1 1 1 0 Centromere-associated protein K DUF2586 PF10758.9 AAZ36301.1 - 1.2e-144 482.0 0.0 1.4e-144 481.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2586) DUF4398 PF14346.6 AAZ36302.1 - 4.4e-09 36.8 16.5 6.2e-09 36.4 16.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4398) ABC_tran_CTD PF16326.5 AAZ36302.1 - 0.0073 16.5 2.2 0.0073 16.5 2.2 2.0 1 1 2 3 3 3 1 ABC transporter C-terminal domain MLTD_N PF06474.12 AAZ36302.1 - 0.24 11.6 2.1 1.7 8.9 0.9 2.5 2 0 0 2 2 2 0 MltD lipid attachment motif ADH_zinc_N PF00107.26 AAZ36303.1 - 1.4e-17 63.9 0.1 2.7e-17 62.9 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AAZ36303.1 - 4.8e-11 43.8 0.0 8.3e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AAZ36303.1 - 1.7e-09 37.5 0.1 3.1e-08 33.4 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Abhydrolase_1 PF00561.20 AAZ36304.1 - 6.3e-21 75.2 0.2 1.1e-20 74.4 0.2 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAZ36304.1 - 2.9e-14 54.2 7.3 3.5e-14 54.0 7.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAZ36304.1 - 7.7e-13 48.3 0.2 1.3e-12 47.6 0.2 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 AAZ36304.1 - 9.3e-10 39.0 0.8 1.4e-09 38.4 0.8 1.5 1 1 0 1 1 1 1 Thioesterase domain Lipase_3 PF01764.25 AAZ36304.1 - 0.017 15.0 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Esterase PF00756.20 AAZ36304.1 - 0.024 14.3 0.0 0.042 13.5 0.0 1.6 1 1 0 1 1 1 0 Putative esterase Ndr PF03096.14 AAZ36304.1 - 0.024 13.3 0.0 0.033 12.9 0.0 1.1 1 0 0 1 1 1 0 Ndr family Glyco_trans_4_4 PF13579.6 AAZ36304.1 - 0.038 14.4 3.1 0.12 12.8 0.7 2.3 2 1 1 3 3 3 0 Glycosyl transferase 4-like domain Abhydrolase_2 PF02230.16 AAZ36304.1 - 0.045 13.5 0.0 0.16 11.7 0.0 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase BAAT_C PF08840.11 AAZ36304.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal PhoD PF09423.10 AAZ36305.1 - 3.2e-83 279.6 0.0 3.9e-83 279.4 0.0 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 AAZ36305.1 - 3e-18 66.1 0.1 5.8e-18 65.2 0.1 1.5 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain NAD_binding_4 PF07993.12 AAZ36306.1 - 1.5e-27 96.4 0.0 2.5e-14 53.1 0.0 2.4 1 1 1 2 2 2 2 Male sterility protein Epimerase PF01370.21 AAZ36306.1 - 1.8e-07 30.9 0.0 4.5e-07 29.6 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 AAZ36306.1 - 2.8e-07 30.6 0.0 4.2e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 AAZ36306.1 - 7.5e-07 28.9 0.0 1.1e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 AAZ36306.1 - 0.00035 19.8 0.0 0.00047 19.4 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 AAZ36306.1 - 0.0024 16.9 0.0 0.0036 16.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 AAZ36306.1 - 0.0039 17.1 0.0 0.0071 16.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 AAZ36306.1 - 0.0071 15.5 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Semialdhyde_dh PF01118.24 AAZ36306.1 - 0.12 12.8 0.0 0.27 11.7 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain MFS_1 PF07690.16 AAZ36307.1 - 3.1e-51 174.3 44.5 3.1e-51 174.3 44.5 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 AAZ36307.1 - 1.4e-08 34.1 12.6 1.4e-08 34.1 12.6 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 AAZ36307.1 - 1.9e-08 33.3 13.9 3.7e-08 32.3 13.9 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 AAZ36307.1 - 0.0065 14.8 20.9 0.025 12.9 1.3 4.0 2 2 2 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 AAZ36307.1 - 5.2 5.8 24.3 0.027 13.3 8.0 2.3 2 0 0 2 2 2 0 MFS_1 like family Aminotran_1_2 PF00155.21 AAZ36308.1 - 3.4e-46 158.1 0.0 3.8e-46 157.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 AAZ36308.1 - 1.2e-06 27.6 0.0 1.8e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Prenyltrans PF00432.21 AAZ36308.1 - 0.054 13.3 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat BPD_transp_1 PF00528.22 AAZ36309.1 - 4e-25 88.6 11.9 7.1e-25 87.8 11.9 1.3 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component Cupin_6 PF12852.7 AAZ36310.1 - 2.9e-30 105.4 7.5 4e-30 104.9 4.3 2.1 2 0 0 2 2 2 1 Cupin HTH_18 PF12833.7 AAZ36310.1 - 8.1e-19 67.7 2.0 1.4e-18 66.9 2.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAZ36310.1 - 4.4e-15 55.3 0.0 5.4e-08 32.7 0.0 2.3 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family AraC_binding PF02311.19 AAZ36310.1 - 0.012 15.5 0.0 0.082 12.8 0.0 2.3 2 0 0 2 2 2 0 AraC-like ligand binding domain Cupin_2 PF07883.11 AAZ36310.1 - 0.051 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Cupin domain TP_methylase PF00590.20 AAZ36311.1 - 3.8e-45 154.4 0.1 4.3e-45 154.3 0.1 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases VPS13_C PF16909.5 AAZ36311.1 - 0.044 13.5 0.0 0.07 12.9 0.0 1.3 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal Peptidase_S24 PF00717.23 AAZ36312.1 - 5.5e-14 51.9 0.0 8e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like HTH_3 PF01381.22 AAZ36312.1 - 4.6e-10 39.4 0.0 7.8e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 AAZ36312.1 - 2.2e-07 31.1 0.0 5.8e-07 29.8 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 AAZ36312.1 - 4e-05 23.5 0.0 6.5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain YdaS_antitoxin PF15943.5 AAZ36312.1 - 0.00029 20.6 0.0 0.00048 19.9 0.0 1.3 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_26 PF13443.6 AAZ36312.1 - 0.00057 20.3 0.0 0.00098 19.5 0.0 1.3 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_37 PF13744.6 AAZ36312.1 - 0.013 15.4 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 AAZ36312.1 - 0.028 14.1 0.0 0.06 13.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 DUF746 PF05344.11 AAZ36312.1 - 0.091 12.6 0.1 0.28 11.1 0.0 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF746) HTH_24 PF13412.6 AAZ36312.1 - 0.17 11.5 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding CTI PF06934.11 AAZ36313.1 - 3.1e-283 941.6 0.0 3.5e-283 941.4 0.0 1.0 1 0 0 1 1 1 1 Fatty acid cis/trans isomerase (CTI) Band_7 PF01145.25 AAZ36314.1 - 5.7e-25 88.3 1.8 5.7e-25 88.3 1.8 1.7 2 0 0 2 2 2 1 SPFH domain / Band 7 family DivIVA PF05103.13 AAZ36314.1 - 0.017 15.2 10.1 0.032 14.3 10.1 1.4 1 0 0 1 1 1 0 DivIVA protein HAUS-augmin3 PF14932.6 AAZ36314.1 - 0.04 13.5 2.3 0.055 13.0 2.3 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 HrpE PF06188.12 AAZ36314.1 - 0.043 13.7 6.6 0.094 12.6 6.6 1.5 1 0 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E ATP-synt_B PF00430.18 AAZ36314.1 - 0.59 10.2 16.0 0.41 10.7 12.0 2.1 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) Trypsin_2 PF13365.6 AAZ36315.1 - 4.1e-31 108.9 0.4 6.2e-31 108.3 0.4 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 AAZ36315.1 - 3.6e-15 56.1 0.1 1.5e-14 54.1 0.0 2.0 2 0 0 2 2 2 1 PDZ domain Trypsin PF00089.26 AAZ36315.1 - 4.9e-14 52.7 0.1 7.4e-14 52.1 0.1 1.2 1 0 0 1 1 1 1 Trypsin PDZ PF00595.24 AAZ36315.1 - 3.7e-11 43.2 1.9 5.9e-10 39.4 0.3 2.7 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 AAZ36315.1 - 8.2e-08 32.0 3.4 2.2e-07 30.6 0.3 2.7 2 0 0 2 2 2 1 PDZ domain Peptidase_S46 PF10459.9 AAZ36315.1 - 0.0016 17.2 0.5 0.63 8.6 0.4 2.2 2 0 0 2 2 2 2 Peptidase S46 Peptidase_S32 PF05579.13 AAZ36315.1 - 0.029 13.6 0.4 0.38 9.9 0.4 2.1 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 Tricorn_PDZ PF14685.6 AAZ36315.1 - 0.11 12.5 0.1 0.26 11.3 0.1 1.6 1 0 0 1 1 1 0 Tricorn protease PDZ domain IstB_IS21 PF01695.17 AAZ36316.1 - 2.7e-14 53.3 0.0 4.4e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein HTH_7 PF02796.15 AAZ36316.1 - 1.6e-06 28.0 0.2 5.4e-06 26.4 0.2 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_38 PF13936.6 AAZ36316.1 - 2.4e-06 27.2 0.2 3.8e-06 26.6 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 AAZ36316.1 - 5.9e-06 25.9 0.2 8.6e-06 25.3 0.2 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 AAZ36316.1 - 1.2e-05 25.0 0.5 4e-05 23.3 0.1 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 AAZ36316.1 - 3.5e-05 23.7 0.0 0.00013 21.9 0.0 2.0 2 0 0 2 2 1 1 Winged helix-turn helix HTH_28 PF13518.6 AAZ36316.1 - 0.00014 21.9 0.6 0.00031 20.8 0.1 1.8 2 0 0 2 2 1 1 Helix-turn-helix domain HTH_10 PF04967.12 AAZ36316.1 - 0.00037 20.2 0.0 0.00066 19.4 0.0 1.4 1 0 0 1 1 1 1 HTH DNA binding domain HTH_8 PF02954.19 AAZ36316.1 - 0.00039 20.1 0.0 0.00079 19.2 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family HTH_11 PF08279.12 AAZ36316.1 - 0.00044 20.2 0.0 0.00098 19.0 0.0 1.6 1 0 0 1 1 1 1 HTH domain HTH_30 PF13556.6 AAZ36316.1 - 0.0005 19.8 0.0 0.001 18.8 0.0 1.5 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain GerE PF00196.19 AAZ36316.1 - 0.0016 17.9 0.0 0.0025 17.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_36 PF13730.6 AAZ36316.1 - 0.0027 17.6 0.0 0.0052 16.7 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain NUMOD1 PF07453.13 AAZ36316.1 - 0.0047 17.2 0.0 0.0071 16.6 0.0 1.3 1 0 0 1 1 1 1 NUMOD1 domain HTH_22 PF13309.6 AAZ36316.1 - 0.0052 16.8 0.0 0.01 15.9 0.0 1.5 1 0 0 1 1 1 1 HTH domain HTH_3 PF01381.22 AAZ36316.1 - 0.0078 16.2 0.0 0.018 15.1 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix HTH_24 PF13412.6 AAZ36316.1 - 0.0081 15.7 0.4 0.018 14.6 0.1 1.7 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.16 AAZ36316.1 - 0.0094 15.5 0.2 0.017 14.7 0.2 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 TnsD PF15978.5 AAZ36316.1 - 0.0099 14.9 0.0 0.012 14.7 0.0 1.1 1 0 0 1 1 1 1 Tn7-like transposition protein D Phage_NinH PF06322.11 AAZ36316.1 - 0.012 15.5 0.2 0.026 14.4 0.1 1.6 2 0 0 2 2 1 0 Phage NinH protein HTH_17 PF12728.7 AAZ36316.1 - 0.019 15.1 0.0 0.035 14.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Terminase_5 PF06056.12 AAZ36316.1 - 0.02 14.7 0.0 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) Sigma70_ECF PF07638.11 AAZ36316.1 - 0.021 14.7 0.1 0.03 14.2 0.1 1.3 1 0 0 1 1 1 0 ECF sigma factor HTH_IclR PF09339.10 AAZ36316.1 - 0.022 14.6 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain DUF2089 PF09862.9 AAZ36316.1 - 0.023 14.7 0.0 0.032 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) HTH_Tnp_1 PF01527.20 AAZ36316.1 - 0.026 14.8 0.2 0.058 13.7 0.0 1.7 2 0 0 2 2 2 0 Transposase Poly_export PF02563.16 AAZ36317.1 - 2.1e-14 53.5 0.0 3.5e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis/export protein SLBB PF10531.9 AAZ36317.1 - 4.8e-05 23.2 0.7 0.00013 21.8 0.7 1.7 1 0 0 1 1 1 1 SLBB domain Abhydrolase_1 PF00561.20 AAZ36319.1 - 3e-19 69.7 0.0 2e-15 57.1 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAZ36319.1 - 1.3e-17 65.1 4.7 1.2e-16 62.0 4.2 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAZ36319.1 - 6.3e-07 28.9 0.0 3.8e-06 26.3 0.0 2.1 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Ndr PF03096.14 AAZ36319.1 - 8.2e-05 21.4 0.0 8.2e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 Ndr family RuvB_N PF05496.12 AAZ36320.1 - 4e-82 273.7 0.0 5.7e-82 273.2 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_4 PF17864.1 AAZ36320.1 - 6.5e-33 112.3 0.6 1.1e-32 111.5 0.6 1.4 1 0 0 1 1 1 1 RuvB AAA lid domain RuvB_C PF05491.13 AAZ36320.1 - 2.8e-26 91.2 0.0 7.1e-26 89.9 0.0 1.7 1 0 0 1 1 1 1 RuvB C-terminal winged helix domain AAA PF00004.29 AAZ36320.1 - 2.3e-19 70.1 0.0 4.2e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AAZ36320.1 - 1.4e-06 28.4 0.1 0.018 15.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 AAZ36320.1 - 0.0002 20.7 0.6 0.00095 18.5 0.0 2.0 2 0 0 2 2 2 1 TIP49 P-loop domain Mg_chelatase PF01078.21 AAZ36320.1 - 0.00023 20.6 0.3 0.085 12.2 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 AAZ36320.1 - 0.0003 21.1 0.2 0.054 13.8 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.11 AAZ36320.1 - 0.00058 19.7 0.0 0.17 11.8 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 AAZ36320.1 - 0.00098 18.9 0.0 1.1 9.0 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain Rad17 PF03215.15 AAZ36320.1 - 0.006 16.5 0.0 0.0094 15.9 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_14 PF13173.6 AAZ36320.1 - 0.0063 16.6 0.0 0.016 15.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 AAZ36320.1 - 0.0092 15.1 0.0 0.02 13.9 0.0 1.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_16 PF13191.6 AAZ36320.1 - 0.0092 16.4 0.2 0.14 12.5 0.0 2.4 2 1 0 3 3 2 1 AAA ATPase domain AAA_17 PF13207.6 AAZ36320.1 - 0.0093 16.4 0.0 0.02 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 AAZ36320.1 - 0.012 16.0 0.0 0.02 15.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 AAZ36320.1 - 0.023 14.4 0.7 0.3 10.8 0.1 2.5 2 1 0 2 2 2 0 IstB-like ATP binding protein AAA_18 PF13238.6 AAZ36320.1 - 0.027 15.0 0.0 0.072 13.6 0.0 1.7 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.27 AAZ36320.1 - 0.031 14.8 0.0 0.06 13.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter NTPase_1 PF03266.15 AAZ36320.1 - 0.041 13.8 0.4 0.29 11.0 0.1 2.1 1 1 1 2 2 2 0 NTPase NB-ARC PF00931.22 AAZ36320.1 - 0.048 12.8 0.0 0.67 9.1 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain RsgA_GTPase PF03193.16 AAZ36320.1 - 0.056 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase TsaE PF02367.17 AAZ36320.1 - 0.059 13.4 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 AAZ36320.1 - 0.072 12.8 0.1 0.2 11.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 AAZ36320.1 - 0.097 12.9 0.1 0.26 11.5 0.1 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 AAZ36320.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 AAZ36320.1 - 0.18 12.0 0.2 0.66 10.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain LPG_synthase_TM PF03706.13 AAZ36321.1 - 3.9e-18 66.0 28.8 7.3e-18 65.1 28.8 1.4 1 1 0 1 1 1 1 Lysylphosphatidylglycerol synthase TM region DUF3923 PF13061.6 AAZ36321.1 - 7.6 6.7 16.5 1.9 8.6 1.2 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3923) Peptidase_S11 PF00768.20 AAZ36322.1 - 3.9e-87 291.7 0.0 5.2e-87 291.3 0.0 1.1 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase PBP5_C PF07943.13 AAZ36322.1 - 2.6e-26 91.7 0.4 4e-26 91.1 0.4 1.3 1 0 0 1 1 1 1 Penicillin-binding protein 5, C-terminal domain Beta-lactamase2 PF13354.6 AAZ36322.1 - 2.8e-12 46.6 0.0 4.2e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase enzyme family Peptidase_S13 PF02113.15 AAZ36322.1 - 9.8e-05 21.2 0.9 0.00013 20.8 0.2 1.5 2 0 0 2 2 2 1 D-Ala-D-Ala carboxypeptidase 3 (S13) family Beta-lactamase PF00144.24 AAZ36322.1 - 0.0018 17.6 0.1 0.076 12.2 0.0 2.2 2 0 0 2 2 2 1 Beta-lactamase HTH_Tnp_1 PF01527.20 AAZ36323.1 - 8.7e-09 35.6 2.8 3.5e-08 33.7 2.8 1.8 1 1 0 1 1 1 1 Transposase HTH_28 PF13518.6 AAZ36323.1 - 0.011 15.8 0.1 0.017 15.3 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain MerR_1 PF13411.6 AAZ36323.1 - 0.049 13.7 0.0 0.12 12.5 0.0 1.8 1 1 0 1 1 1 0 MerR HTH family regulatory protein TSC22 PF01166.18 AAZ36323.1 - 0.072 13.4 0.3 0.2 12.0 0.4 1.6 2 0 0 2 2 2 0 TSC-22/dip/bun family IpaC_SipC PF09599.10 AAZ36323.1 - 0.09 12.3 0.0 0.11 12.0 0.0 1.0 1 0 0 1 1 1 0 Salmonella-Shigella invasin protein C (IpaC_SipC) OprD PF03573.13 AAZ36324.1 - 5.3e-134 447.2 9.3 6e-134 447.0 9.3 1.0 1 0 0 1 1 1 1 outer membrane porin, OprD family Phage_GPD PF05954.11 AAZ36326.1 - 4.4e-91 305.3 0.0 8.4e-91 304.4 0.0 1.4 2 0 0 2 2 2 1 Phage late control gene D protein (GPD) DUF2345 PF10106.9 AAZ36326.1 - 0.00045 20.1 0.4 0.00083 19.3 0.4 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2345) Phage_base_V PF04717.12 AAZ36326.1 - 0.0019 18.1 0.0 0.0045 16.9 0.0 1.6 1 0 0 1 1 1 1 Type VI secretion system, phage-baseplate injector Gp5_C PF06715.12 AAZ36326.1 - 0.0063 16.6 6.7 0.02 15.0 2.9 2.9 1 1 1 2 2 2 1 Gp5 C-terminal repeat (3 copies) DJ-1_PfpI PF01965.24 AAZ36327.1 - 8.7e-25 87.4 0.0 1.1e-24 87.1 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family CUE PF02845.16 AAZ36327.1 - 0.045 13.5 0.1 0.084 12.6 0.1 1.4 1 0 0 1 1 1 0 CUE domain HigB_toxin PF09907.9 AAZ36327.1 - 0.14 12.3 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system Ni_hydr_CYTB PF01292.20 AAZ36328.1 - 1.5e-25 89.9 21.6 1.7e-25 89.7 21.6 1.0 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 DUF4405 PF14358.6 AAZ36328.1 - 0.0053 17.3 12.5 0.0053 17.3 12.5 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4405) DUF621 PF04789.15 AAZ36328.1 - 0.17 11.1 1.4 0.24 10.5 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF621) ACR_tran PF00873.19 AAZ36329.1 - 0 1100.1 33.1 0 1099.9 33.1 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AAZ36329.1 - 1.3e-09 37.5 5.5 1.3e-09 37.5 5.5 3.8 4 0 0 4 4 4 2 MMPL family SecD_SecF PF02355.16 AAZ36329.1 - 0.00015 21.2 32.2 0.00022 20.7 14.6 2.6 2 0 0 2 2 2 2 Protein export membrane protein Man-6-P_recep PF02157.15 AAZ36329.1 - 0.23 10.5 0.4 0.45 9.6 0.4 1.4 1 0 0 1 1 1 0 Mannose-6-phosphate receptor Patched PF02460.18 AAZ36329.1 - 9.7 4.1 29.4 0.062 11.4 13.9 2.1 2 0 0 2 2 2 0 Patched family LysR_substrate PF03466.20 AAZ36330.1 - 1.4e-35 122.5 0.2 2.1e-35 122.0 0.2 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ36330.1 - 3.8e-21 74.8 3.2 8.1e-21 73.7 3.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family PPS_PS PF02006.16 AAZ36330.1 - 0.01 15.4 0.1 0.016 14.8 0.1 1.2 1 0 0 1 1 1 0 Phosphopantothenate/pantothenate synthetase HTH_IclR PF09339.10 AAZ36330.1 - 0.015 15.0 1.1 0.015 15.0 1.1 2.1 2 0 0 2 2 2 0 IclR helix-turn-helix domain MarR_2 PF12802.7 AAZ36330.1 - 0.035 14.0 2.8 0.079 12.9 0.7 2.4 1 1 1 2 2 2 0 MarR family HTH_50 PF18024.1 AAZ36330.1 - 0.14 11.8 0.1 0.32 10.7 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_18 PF12833.7 AAZ36331.1 - 1.2e-24 86.4 0.8 2.4e-24 85.4 0.8 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAZ36331.1 - 4.3e-19 68.1 0.0 8.6e-10 38.5 0.0 2.8 3 0 0 3 3 3 2 Bacterial regulatory helix-turn-helix proteins, AraC family AraC_binding PF02311.19 AAZ36331.1 - 1.2e-07 31.7 0.2 2.4e-07 30.7 0.2 1.5 1 0 0 1 1 1 1 AraC-like ligand binding domain Transposase_mut PF00872.18 AAZ36332.1 - 2.6e-116 388.6 0.0 3.2e-116 388.3 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ36332.1 - 7.7e-05 23.0 0.0 0.00021 21.6 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain GCV_T PF01571.21 AAZ36333.1 - 8.4e-93 310.4 0.0 1.1e-92 310.0 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 AAZ36333.1 - 1e-17 63.8 0.1 2.3e-17 62.7 0.1 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.12 AAZ36333.1 - 0.00028 21.1 0.0 0.018 15.2 0.0 2.2 1 1 1 2 2 2 2 Sarcosine oxidase, gamma subunit family FA_desaturase PF00487.24 AAZ36334.1 - 2.9e-40 138.7 21.1 2.9e-40 138.7 21.1 1.9 1 1 1 2 2 2 2 Fatty acid desaturase MFS_1 PF07690.16 AAZ36335.1 - 4.3e-11 42.3 51.4 4.3e-11 42.3 51.4 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily KdpA PF03814.15 AAZ36336.1 - 7.8e-236 783.5 26.7 9.6e-236 783.2 26.7 1.0 1 0 0 1 1 1 1 Potassium-transporting ATPase A subunit NLPC_P60 PF00877.19 AAZ36337.1 - 1.7e-29 102.0 0.0 2.7e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 NlpC/P60 family DUF1175 PF06672.11 AAZ36337.1 - 0.00027 20.7 0.0 0.19 11.4 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF1175) Peptidase_C92 PF05708.12 AAZ36337.1 - 0.0018 18.4 0.0 0.98 9.5 0.0 2.4 2 0 0 2 2 2 2 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family LRAT PF04970.13 AAZ36337.1 - 0.0084 16.4 0.4 0.038 14.3 0.0 2.2 3 0 0 3 3 3 1 Lecithin retinol acyltransferase Prot_ATP_ID_OB PF16450.5 AAZ36337.1 - 0.074 13.0 0.1 0.56 10.2 0.0 2.4 3 0 0 3 3 3 0 Proteasomal ATPase OB C-terminal domain NTP_transf_2 PF01909.23 AAZ36338.1 - 0.056 13.7 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain DUF4096 PF13340.6 AAZ36339.1 - 5.8e-25 87.3 0.4 1.5e-24 86.0 0.4 1.8 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1 PF01609.21 AAZ36339.1 - 3.2e-14 53.1 0.0 5.7e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AAZ36339.1 - 7.2e-10 39.1 0.2 2.1e-09 37.6 0.2 1.9 1 0 0 1 1 1 1 Transposase DDE domain HTH_Tnp_Tc3_2 PF01498.18 AAZ36339.1 - 0.061 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Transposase tRNA_synt_2f PF02092.17 AAZ36340.1 - 3.7e-205 682.9 0.0 4.5e-205 682.6 0.0 1.1 1 0 0 1 1 1 1 Glycyl-tRNA synthetase beta subunit DALR_1 PF05746.15 AAZ36340.1 - 1.3e-07 31.8 0.4 3e-07 30.6 0.4 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain SHMT PF00464.19 AAZ36341.1 - 1.3e-181 603.6 0.2 1.5e-181 603.3 0.2 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 AAZ36341.1 - 1.4e-08 34.3 0.0 2e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 AAZ36341.1 - 4e-06 26.3 0.1 9.5e-06 25.1 0.1 1.3 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 AAZ36341.1 - 0.00026 20.1 0.0 0.00037 19.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 AAZ36341.1 - 0.0022 17.4 0.0 0.003 16.9 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 AAZ36341.1 - 0.011 14.3 0.0 0.016 13.8 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Glyco_hydro_19 PF00182.19 AAZ36342.1 - 5.1e-10 39.6 0.0 1.3e-09 38.3 0.0 1.6 1 1 0 1 1 1 1 Chitinase class I Phytase PF02333.15 AAZ36343.1 - 4.8e-86 289.1 0.0 5.9e-80 269.0 0.0 2.2 2 0 0 2 2 2 2 Phytase Lactonase PF10282.9 AAZ36343.1 - 0.044 13.0 0.1 0.31 10.3 0.0 2.2 2 1 0 2 2 2 0 Lactonase, 7-bladed beta-propeller CsbD PF05532.12 AAZ36344.1 - 8.2e-18 64.1 17.8 9.3e-18 63.9 17.8 1.0 1 0 0 1 1 1 1 CsbD-like Alanine_zipper PF11839.8 AAZ36344.1 - 0.0019 18.5 3.6 0.4 11.1 0.2 2.1 1 1 1 2 2 2 2 Alanine-zipper, major outer membrane lipoprotein MT0933_antitox PF14013.6 AAZ36344.1 - 0.0047 17.2 15.9 0.16 12.3 15.9 2.1 1 1 0 1 1 1 1 MT0933-like antitoxin protein Apolipoprotein PF01442.18 AAZ36344.1 - 0.016 15.1 0.4 0.016 15.1 0.4 1.0 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain GFO_IDH_MocA PF01408.22 AAZ36345.1 - 4.5e-26 92.0 0.2 7.8e-26 91.3 0.2 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 AAZ36345.1 - 9.1e-09 35.3 0.0 1.7e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain 2-Hacid_dh_C PF02826.19 AAZ36345.1 - 0.00073 18.9 0.2 0.034 13.5 0.1 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 AAZ36345.1 - 0.006 17.1 0.0 0.016 15.8 0.2 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 AAZ36345.1 - 0.064 13.5 0.5 0.18 12.1 0.5 1.8 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Peptidase_M16_C PF05193.21 AAZ36346.1 - 7.4e-27 94.5 0.0 9.2e-26 91.0 0.0 2.1 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 AAZ36346.1 - 2.5e-20 73.0 0.0 4.2e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Drf_DAD PF06345.11 AAZ36346.1 - 0.35 11.0 1.3 0.99 9.6 1.3 1.8 1 0 0 1 1 1 0 DRF Autoregulatory Domain Aldo_ket_red PF00248.21 AAZ36347.1 - 1.1e-82 277.6 0.0 1.4e-82 277.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Transpeptidase PF00905.22 AAZ36348.1 - 2.6e-80 269.9 0.2 3.2e-80 269.6 0.2 1.1 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain PBP_dimer PF03717.15 AAZ36348.1 - 1.3e-18 67.9 0.0 1.8e-16 61.0 0.0 2.8 2 1 0 2 2 2 1 Penicillin-binding Protein dimerisation domain AsnC_trans_reg PF01037.21 AAZ36349.1 - 1.8e-23 82.3 0.0 2.9e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_AsnC-type PF13404.6 AAZ36349.1 - 4.3e-17 61.7 0.2 7.7e-17 60.8 0.2 1.5 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 AAZ36349.1 - 3e-15 55.5 0.1 6.2e-15 54.5 0.1 1.6 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 AAZ36349.1 - 1.2e-05 25.3 0.0 2.4e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 AAZ36349.1 - 9.8e-05 22.3 0.2 0.00016 21.6 0.2 1.3 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain MarR_2 PF12802.7 AAZ36349.1 - 0.00018 21.4 0.1 0.00037 20.3 0.1 1.6 1 0 0 1 1 1 1 MarR family HTH_11 PF08279.12 AAZ36349.1 - 0.00019 21.3 0.7 0.00039 20.3 0.1 1.8 2 0 0 2 2 2 1 HTH domain HTH_47 PF16221.5 AAZ36349.1 - 0.00031 20.2 0.0 0.00048 19.6 0.0 1.3 1 0 0 1 1 1 1 winged helix-turn-helix MarR PF01047.22 AAZ36349.1 - 0.0028 17.5 0.0 0.0047 16.8 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_28 PF13518.6 AAZ36349.1 - 0.0069 16.5 0.2 0.012 15.7 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 AAZ36349.1 - 0.009 15.4 0.1 0.018 14.5 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_CodY PF08222.11 AAZ36349.1 - 0.015 14.9 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 CodY helix-turn-helix domain HTH_IclR PF09339.10 AAZ36349.1 - 0.017 14.9 0.0 0.038 13.8 0.0 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain TrmB PF01978.19 AAZ36349.1 - 0.032 14.1 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_36 PF13730.6 AAZ36349.1 - 0.041 13.8 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain LexA_DNA_bind PF01726.16 AAZ36349.1 - 0.065 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 LexA DNA binding domain Sigma70_r4_2 PF08281.12 AAZ36349.1 - 0.17 11.5 0.0 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 Sigma-70, region 4 CesT PF05932.13 AAZ36350.1 - 3.9e-06 27.0 0.0 4.8e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Tir chaperone protein (CesT) family RelB PF04221.12 AAZ36351.1 - 8e-17 61.0 0.1 8.2e-17 61.0 0.1 1.0 1 0 0 1 1 1 1 RelB antitoxin RHH_1 PF01402.21 AAZ36351.1 - 0.75 9.8 3.7 1.2 9.2 0.1 2.9 3 1 0 3 3 3 0 Ribbon-helix-helix protein, copG family BPD_transp_1 PF00528.22 AAZ36352.1 - 5.7e-20 71.8 19.0 5.7e-20 71.8 19.0 1.7 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF525 PF04379.14 AAZ36353.1 - 2.2e-34 117.6 0.2 2.7e-34 117.2 0.2 1.1 1 0 0 1 1 1 1 ApaG domain Enolase_C PF00113.22 AAZ36355.1 - 1.4e-137 457.9 0.6 1.7e-137 457.6 0.6 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 AAZ36355.1 - 3.1e-57 192.4 0.1 6.2e-57 191.4 0.1 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MAAL_C PF07476.11 AAZ36355.1 - 4.7e-06 25.9 1.0 6e-06 25.6 0.1 1.6 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus MR_MLE_C PF13378.6 AAZ36355.1 - 5.1e-06 26.2 0.0 8.9e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like FlaG PF03646.15 AAZ36356.1 - 4.3e-22 78.2 0.2 5.3e-22 77.9 0.2 1.1 1 0 0 1 1 1 1 FlaG protein Bac_export_3 PF01313.19 AAZ36357.1 - 8.9e-23 80.0 6.5 1e-22 79.9 6.5 1.0 1 0 0 1 1 1 1 Bacterial export proteins, family 3 2-Hacid_dh_C PF02826.19 AAZ36358.1 - 6e-46 156.0 0.0 7.7e-46 155.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 AAZ36358.1 - 1.3e-20 73.4 0.0 1.5e-20 73.2 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 AAZ36358.1 - 5.5e-05 23.4 0.0 9.9e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase GntR PF00392.21 AAZ36359.1 - 9.5e-19 66.8 1.0 2.9e-18 65.3 1.0 1.9 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family FCD PF07729.12 AAZ36359.1 - 4.3e-16 59.5 3.3 7.9e-16 58.6 3.3 1.4 1 0 0 1 1 1 1 FCD domain HTH_Crp_2 PF13545.6 AAZ36359.1 - 0.0015 18.4 0.9 0.0044 17.0 0.2 2.1 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_24 PF13412.6 AAZ36359.1 - 0.0017 17.9 0.5 0.061 12.9 0.1 2.7 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_DeoR PF08220.12 AAZ36359.1 - 0.0029 17.3 0.0 0.007 16.1 0.0 1.7 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain MarR PF01047.22 AAZ36359.1 - 0.013 15.4 0.3 0.038 13.9 0.1 1.9 2 0 0 2 2 2 0 MarR family HTH_11 PF08279.12 AAZ36359.1 - 0.031 14.2 0.0 0.094 12.7 0.0 1.8 1 0 0 1 1 1 0 HTH domain MarR_2 PF12802.7 AAZ36359.1 - 0.078 12.9 1.2 0.21 11.5 0.1 2.3 3 0 0 3 3 3 0 MarR family HTH_10 PF04967.12 AAZ36359.1 - 0.11 12.3 0.1 1.7 8.5 0.0 2.7 3 0 0 3 3 3 0 HTH DNA binding domain Transposase_mut PF00872.18 AAZ36360.1 - 1.5e-117 392.7 0.0 1.9e-117 392.3 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ36360.1 - 7.7e-05 23.0 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain DUF4844 PF16133.5 AAZ36360.1 - 0.23 12.0 0.0 0.55 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) LysR_substrate PF03466.20 AAZ36361.1 - 2.8e-27 95.5 2.0 4.6e-27 94.7 2.0 1.4 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ36361.1 - 2.2e-12 46.7 0.6 5.2e-12 45.5 0.6 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_23 PF13384.6 AAZ36361.1 - 0.0025 17.6 0.2 0.0064 16.3 0.2 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 AAZ36361.1 - 0.021 15.0 0.2 0.056 13.6 0.2 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_11 PF08279.12 AAZ36361.1 - 0.13 12.3 0.1 0.28 11.2 0.1 1.6 1 0 0 1 1 1 0 HTH domain HTH_Tnp_ISL3 PF13542.6 AAZ36361.1 - 0.18 11.2 1.8 0.4 10.1 0.3 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Sigma70_r4_2 PF08281.12 AAZ36361.1 - 0.33 10.7 3.6 11 5.7 0.9 2.5 2 0 0 2 2 2 0 Sigma-70, region 4 TetR_C_3 PF08362.11 AAZ36362.1 - 9.1e-59 197.5 0.0 1.2e-58 197.1 0.0 1.2 1 0 0 1 1 1 1 YcdC-like protein, C-terminal region TetR_N PF00440.23 AAZ36362.1 - 3.2e-12 46.0 0.0 5.1e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_29 PF17938.1 AAZ36362.1 - 0.00046 20.3 0.0 0.00079 19.5 0.0 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain SecIII_SopE_N PF05364.14 AAZ36362.1 - 0.043 13.9 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 Salmonella type III secretion SopE effector N-terminus ETF_QO PF05187.13 AAZ36363.1 - 2.6e-50 168.9 0.2 4.1e-50 168.3 0.2 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 AAZ36363.1 - 5.6e-10 39.3 1.4 7.5e-05 22.5 0.9 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 AAZ36363.1 - 5.3e-08 32.4 0.0 9.2e-07 28.3 0.2 2.1 1 1 1 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 AAZ36363.1 - 5.5e-08 32.3 1.3 0.00034 19.8 2.7 2.2 1 1 1 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 AAZ36363.1 - 7.4e-08 32.5 0.0 4.8e-07 29.9 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 AAZ36363.1 - 3.9e-05 23.7 0.1 8.3e-05 22.6 0.1 1.7 1 1 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 AAZ36363.1 - 4.5e-05 22.9 0.0 0.00029 20.2 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 AAZ36363.1 - 0.00035 19.8 0.3 0.00055 19.1 0.3 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 AAZ36363.1 - 0.00071 18.4 0.8 0.001 17.8 0.8 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 AAZ36363.1 - 0.0008 18.7 0.0 0.0015 17.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAZ36363.1 - 0.00086 19.8 0.3 0.44 11.1 0.4 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAZ36363.1 - 0.0032 16.8 0.7 0.0046 16.3 0.7 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 AAZ36363.1 - 0.0057 15.8 0.0 0.0086 15.3 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 AAZ36363.1 - 0.0068 15.8 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Fer4_7 PF12838.7 AAZ36363.1 - 0.055 14.1 1.6 0.12 13.0 1.6 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAZ36363.1 - 0.15 12.2 0.7 0.44 10.8 0.7 1.7 1 0 0 1 1 1 0 4Fe-4S binding domain Trp_halogenase PF04820.14 AAZ36363.1 - 0.16 10.8 0.2 0.39 9.5 0.3 1.5 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.22 AAZ36363.1 - 0.49 9.4 1.3 1.3 8.1 0.8 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A FtsL PF04999.13 AAZ36364.1 - 6.4e-33 112.6 0.1 6.9e-33 112.5 0.1 1.0 1 0 0 1 1 1 1 Cell division protein FtsL WHIM1 PF15612.6 AAZ36364.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 DUF1523 PF07509.11 AAZ36365.1 - 1.1e-61 207.3 1.0 1.5e-61 206.9 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1523) DUF1206 PF06724.11 AAZ36365.1 - 1.5 8.9 8.3 5.1 7.3 0.2 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) Gram_pos_anchor PF00746.21 AAZ36365.1 - 1.6 8.8 3.5 1.1 9.3 0.7 1.9 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Sigma70_r2 PF04542.14 AAZ36366.1 - 8.8e-18 63.9 0.6 1.4e-17 63.2 0.1 1.6 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 AAZ36366.1 - 1.3e-13 50.4 0.1 3.1e-13 49.2 0.1 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAZ36366.1 - 1.8e-13 49.8 0.1 4.9e-13 48.4 0.1 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 AAZ36366.1 - 0.00014 21.8 0.2 0.00026 20.9 0.2 1.6 1 1 0 1 1 1 1 ECF sigma factor HTH_24 PF13412.6 AAZ36366.1 - 0.0031 17.0 0.0 0.0071 15.9 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding DUF4032 PF13224.6 AAZ36366.1 - 0.035 14.0 0.1 0.084 12.7 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4032) DUF4164 PF13747.6 AAZ36366.1 - 0.043 14.1 0.2 0.55 10.5 0.2 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) DUF1492 PF07374.11 AAZ36366.1 - 0.11 12.7 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1492) HU-CCDC81_euk_2 PF18289.1 AAZ36366.1 - 0.14 12.4 0.0 3.9 7.7 0.0 2.5 2 0 0 2 2 2 0 CCDC81 eukaryotic HU domain 2 HSCB_C PF07743.13 AAZ36368.1 - 3e-14 53.3 6.4 3e-14 53.3 6.4 1.7 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 AAZ36368.1 - 2.1e-08 34.2 0.1 3.7e-08 33.4 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain ZapB PF06005.12 AAZ36369.1 - 0.37 11.3 9.1 0.51 10.8 9.1 1.1 1 0 0 1 1 1 0 Cell division protein ZapB Atg14 PF10186.9 AAZ36369.1 - 0.46 9.5 4.4 0.45 9.5 4.4 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Neuromodulin_N PF10580.9 AAZ36369.1 - 0.5 10.2 2.7 0.4 10.5 0.8 1.8 2 0 0 2 2 2 0 Gap junction protein N-terminal region YcgL PF05166.13 AAZ36370.1 - 1.4e-28 99.0 0.1 7.4e-28 96.7 0.0 1.8 2 0 0 2 2 2 1 YcgL domain DUF454 PF04304.13 AAZ36371.1 - 1e-40 138.3 4.6 1.2e-40 138.1 4.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF454) UbiA PF01040.18 AAZ36371.1 - 0.00042 19.7 3.7 0.095 12.0 0.2 2.0 2 0 0 2 2 2 2 UbiA prenyltransferase family PGPGW PF09656.10 AAZ36371.1 - 0.079 12.5 3.2 0.2 11.2 3.2 1.7 1 0 0 1 1 1 0 Putative transmembrane protein (PGPGW) UPF0029 PF01205.19 AAZ36372.1 - 2.8e-28 98.3 0.0 3.8e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 DUF1949 PF09186.11 AAZ36372.1 - 1.5e-12 47.2 0.2 9.3e-11 41.4 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF1949) PAS_9 PF13426.7 AAZ36373.1 - 1.7e-27 95.7 0.0 9.3e-16 58.0 0.0 2.7 2 0 0 2 2 2 2 PAS domain HisKA PF00512.25 AAZ36373.1 - 9.7e-25 86.4 0.7 2.1e-20 72.5 0.0 3.0 2 0 0 2 2 2 2 His Kinase A (phospho-acceptor) domain HATPase_c PF02518.26 AAZ36373.1 - 3.5e-22 79.0 0.0 6.2e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.25 AAZ36373.1 - 2.2e-20 72.7 0.0 4.2e-11 42.8 0.0 3.2 3 1 0 3 3 3 2 PAS fold PAS_4 PF08448.10 AAZ36373.1 - 1.8e-18 66.8 0.0 3.2e-13 49.9 0.0 2.7 2 1 0 2 2 2 2 PAS fold PAS_8 PF13188.7 AAZ36373.1 - 6.2e-06 26.1 0.0 0.00043 20.2 0.0 3.0 3 0 0 3 3 3 1 PAS domain PAS_3 PF08447.12 AAZ36373.1 - 0.011 16.0 0.0 0.72 10.2 0.0 2.7 2 0 0 2 2 2 0 PAS fold DUF4124 PF13511.6 AAZ36374.1 - 0.00052 20.3 1.4 0.0015 18.8 1.4 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4124) Pro_CA PF00484.19 AAZ36375.1 - 1.3e-49 168.5 0.1 1.6e-49 168.2 0.1 1.1 1 0 0 1 1 1 1 Carbonic anhydrase SieB PF14163.6 AAZ36375.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Super-infection exclusion protein B Transposase_mut PF00872.18 AAZ36376.1 - 7.6e-117 390.4 0.0 9.5e-117 390.1 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ36376.1 - 7.9e-05 23.0 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain Peptidase_M20 PF01546.28 AAZ36377.1 - 3.5e-35 121.6 0.0 5.2e-35 121.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AAZ36377.1 - 5.8e-24 84.1 0.0 9.8e-24 83.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF2007 PF09413.10 AAZ36377.1 - 0.097 12.9 0.2 0.28 11.4 0.0 1.9 2 0 0 2 2 2 0 Putative prokaryotic signal transducing protein DPBB_1 PF03330.18 AAZ36378.1 - 4.1e-25 87.9 0.0 7.4e-25 87.1 0.0 1.4 1 0 0 1 1 1 1 Lytic transglycolase SPOR PF05036.13 AAZ36378.1 - 1.8e-13 50.7 0.1 3.8e-13 49.6 0.1 1.6 1 0 0 1 1 1 1 Sporulation related domain Sigma54_DBD PF04552.13 AAZ36379.1 - 2.3e-71 238.7 0.5 3.7e-71 238.0 0.5 1.3 1 0 0 1 1 1 1 Sigma-54, DNA binding domain Sigma54_CBD PF04963.13 AAZ36379.1 - 2.2e-63 213.3 0.8 6.2e-63 211.9 0.8 1.8 1 0 0 1 1 1 1 Sigma-54 factor, core binding domain Sigma54_AID PF00309.20 AAZ36379.1 - 8.8e-17 60.7 12.8 8.8e-17 60.7 12.8 2.2 2 0 0 2 2 2 1 Sigma-54 factor, Activator interacting domain (AID) CCDC14 PF15254.6 AAZ36379.1 - 0.017 13.8 0.0 0.027 13.1 0.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 TrmO_C PF18389.1 AAZ36379.1 - 0.17 12.0 3.7 1.2 9.3 0.1 2.8 2 0 0 2 2 2 0 TrmO C-terminal domain HATPase_c PF02518.26 AAZ36380.1 - 1.8e-18 67.1 0.0 4.2e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 AAZ36380.1 - 3.9e-09 36.7 0.1 1.2e-08 35.2 0.1 1.9 1 0 0 1 1 1 1 HAMP domain HisKA PF00512.25 AAZ36380.1 - 5e-09 36.1 0.5 3.4e-08 33.4 0.3 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain NIT PF08376.10 AAZ36380.1 - 0.0094 16.4 0.1 0.017 15.6 0.1 1.4 1 0 0 1 1 1 1 Nitrate and nitrite sensing HATPase_c_2 PF13581.6 AAZ36380.1 - 0.042 13.8 0.0 0.093 12.7 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain ABC_tran PF00005.27 AAZ36382.1 - 3e-26 92.6 0.0 4.3e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 AAZ36382.1 - 3.6e-15 56.2 0.3 7.6e-15 55.2 0.3 1.6 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_22 PF13401.6 AAZ36382.1 - 6.6e-07 29.7 0.1 2.4e-05 24.7 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 AAZ36382.1 - 1.5e-06 28.3 0.1 6.8e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 AAZ36382.1 - 0.0095 16.4 0.0 0.036 14.5 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AAZ36382.1 - 0.018 15.4 0.6 0.038 14.4 0.6 1.6 1 1 0 1 1 1 0 AAA ATPase domain Mg_chelatase PF01078.21 AAZ36382.1 - 0.089 12.2 0.1 0.17 11.3 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 AAZ36382.1 - 0.095 12.6 0.1 0.22 11.4 0.0 1.6 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 AAZ36382.1 - 0.11 12.2 0.0 1.4 8.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 AAZ36382.1 - 0.11 12.6 0.0 0.22 11.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 AAZ36382.1 - 0.14 11.6 0.0 18 4.7 0.0 2.4 3 0 0 3 3 3 0 Bacterial TniB protein GST_N_2 PF13409.6 AAZ36383.1 - 2.8e-06 27.5 0.0 4.9e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 AAZ36383.1 - 4.9e-05 23.6 0.0 8.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 AAZ36383.1 - 0.015 15.6 0.0 0.025 14.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain ImcF-related_N PF14331.6 AAZ36384.1 - 2e-55 188.0 1.6 3.8e-55 187.0 1.6 1.5 1 0 0 1 1 1 1 ImcF-related N-terminal domain IcmF-related PF06761.12 AAZ36384.1 - 1e-48 166.4 0.4 3.4e-48 164.7 0.4 2.0 1 1 0 1 1 1 1 Intracellular multiplication and human macrophage-killing IcmF_C PF06744.12 AAZ36384.1 - 3.2e-38 131.4 0.0 6.3e-38 130.4 0.0 1.5 1 0 0 1 1 1 1 Type VI secretion protein IcmF C-terminal MMR_HSR1 PF01926.23 AAZ36384.1 - 0.00014 21.9 0.0 0.0055 16.8 0.0 3.3 4 0 0 4 4 4 1 50S ribosome-binding GTPase CHAD PF05235.14 AAZ36384.1 - 2.3 8.1 8.7 0.51 10.3 0.2 3.4 3 1 0 3 3 3 0 CHAD domain ADH_zinc_N_2 PF13602.6 AAZ36385.1 - 2.7e-29 102.9 0.4 6.5e-29 101.7 0.4 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 AAZ36385.1 - 9.3e-14 51.5 0.2 1.7e-13 50.7 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AAZ36385.1 - 4.2e-09 36.3 0.0 1.1e-08 34.9 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 AAZ36385.1 - 1.8e-05 24.1 0.2 3e-05 23.4 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain YjeF_N PF03853.15 AAZ36385.1 - 0.094 12.6 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus ADH_N_2 PF16884.5 AAZ36385.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Frataxin_Cyay PF01491.16 AAZ36386.1 - 1.6e-23 82.8 0.0 1.9e-23 82.6 0.0 1.0 1 0 0 1 1 1 1 Frataxin-like domain HSP70 PF00012.20 AAZ36387.1 - 1.1e-138 463.1 0.0 5.6e-119 398.0 0.0 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 AAZ36387.1 - 2.8e-13 49.4 0.0 2e-12 46.6 0.0 2.2 1 1 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.16 AAZ36387.1 - 0.00013 21.8 0.1 0.00026 20.8 0.1 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Raco_middle PF17651.1 AAZ36387.1 - 0.075 12.7 0.0 0.35 10.6 0.0 2.1 2 0 0 2 2 2 0 RACo middle region FtsA PF14450.6 AAZ36387.1 - 0.17 12.3 0.0 52 4.3 0.0 3.4 2 2 0 2 2 2 0 Cell division protein FtsA Pentapeptide PF00805.22 AAZ36388.1 - 7.8e-10 38.2 0.3 0.00013 21.5 0.1 2.2 1 1 1 2 2 2 2 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 AAZ36388.1 - 0.00072 19.7 0.0 0.0011 19.1 0.0 1.2 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 AAZ36388.1 - 0.11 12.7 0.0 0.33 11.1 0.0 1.7 1 1 0 1 1 1 0 Pentapeptide repeats (9 copies) DDE_Tnp_1 PF01609.21 AAZ36389.1 - 2.3e-36 125.5 1.3 4.1e-36 124.6 0.9 1.5 2 0 0 2 2 2 1 Transposase DDE domain DUF772 PF05598.11 AAZ36389.1 - 1.7e-19 69.6 0.0 3.6e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 Transposase domain (DUF772) DDE_Tnp_1_6 PF13751.6 AAZ36389.1 - 2.4e-06 27.8 0.8 4.9e-06 26.8 0.8 1.5 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 AAZ36389.1 - 1e-05 25.6 0.1 1.6e-05 25.0 0.1 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 AAZ36389.1 - 0.00042 20.0 0.9 0.0007 19.3 0.9 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease ParA PF10609.9 AAZ36390.1 - 3.4e-22 79.1 0.2 5.7e-22 78.3 0.2 1.3 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 AAZ36390.1 - 2.9e-18 66.1 0.0 5e-18 65.4 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 AAZ36390.1 - 1.5e-16 60.8 0.0 2.2e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.18 AAZ36390.1 - 2.6e-13 50.1 0.1 1.1e-12 48.0 0.1 1.9 1 1 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 AAZ36390.1 - 1.1e-08 34.8 0.2 2.2e-08 33.9 0.2 1.5 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ArsA_ATPase PF02374.15 AAZ36390.1 - 6.5e-07 28.8 1.1 4.8e-06 26.0 0.3 2.3 2 1 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.11 AAZ36390.1 - 1.4e-05 24.5 0.3 3.5e-05 23.2 0.3 1.7 1 1 0 1 1 1 1 ATPase MipZ AAA_24 PF13479.6 AAZ36390.1 - 0.00067 19.4 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_26 PF13500.6 AAZ36390.1 - 0.0057 16.5 0.6 0.43 10.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 AAZ36390.1 - 0.0079 15.8 1.0 0.039 13.5 0.9 2.1 1 1 0 1 1 1 1 AAA domain VirC1 PF07015.11 AAZ36390.1 - 0.013 14.9 0.2 0.038 13.3 0.1 1.8 2 0 0 2 2 2 0 VirC1 protein CLP1_P PF16575.5 AAZ36390.1 - 0.061 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop APS_kinase PF01583.20 AAZ36390.1 - 0.13 12.1 0.5 0.3 11.0 0.1 1.7 2 0 0 2 2 2 0 Adenylylsulphate kinase FTHFS PF01268.19 AAZ36390.1 - 0.16 10.1 0.1 0.25 9.5 0.1 1.2 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase PIF PF05092.12 AAZ36390.1 - 0.2 10.3 0.0 0.27 9.9 0.0 1.1 1 0 0 1 1 1 0 Per os infectivity MeaB PF03308.16 AAZ36390.1 - 0.82 8.6 3.4 4.8 6.1 0.3 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PGM_PMM_I PF02878.16 AAZ36391.1 - 1.7e-35 121.7 0.0 2.9e-34 117.7 0.0 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 AAZ36391.1 - 1.1e-29 102.9 0.0 2e-29 102.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 AAZ36391.1 - 7.6e-16 58.6 0.0 1.6e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 AAZ36391.1 - 3.1e-09 36.9 0.0 8e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain N_methyl PF07963.12 AAZ36392.1 - 1e-10 40.7 4.0 1.8e-10 39.9 4.0 1.4 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif Pilin PF00114.19 AAZ36392.1 - 0.003 18.5 11.8 0.0089 16.9 11.8 1.6 1 1 0 1 1 1 1 Pilin (bacterial filament) Herpes_capsid PF06112.11 AAZ36392.1 - 1.2 9.1 6.7 1.5 8.9 6.7 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein PGF-CTERM PF18204.1 AAZ36392.1 - 3.9 7.6 6.8 11 6.2 6.8 1.8 1 0 0 1 1 1 0 PGF-CTERM motif Epimerase PF01370.21 AAZ36393.1 - 1.8e-42 145.5 0.0 2.4e-42 145.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Formyl_trans_N PF00551.19 AAZ36393.1 - 6.8e-27 94.4 0.0 1e-26 93.8 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase GDP_Man_Dehyd PF16363.5 AAZ36393.1 - 4.2e-23 82.3 0.0 5.5e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Formyl_trans_C PF02911.18 AAZ36393.1 - 1.7e-16 60.3 0.0 3.9e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain 3Beta_HSD PF01073.19 AAZ36393.1 - 0.00014 21.0 0.0 0.00019 20.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 AAZ36393.1 - 0.002 18.0 0.0 0.0035 17.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding TrkA_N PF02254.18 AAZ36393.1 - 0.0038 17.5 0.0 0.0081 16.4 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 AAZ36393.1 - 0.012 15.9 0.0 0.053 13.8 0.0 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 AAZ36393.1 - 0.057 12.6 0.0 2.2 7.4 0.0 2.2 1 1 0 1 1 1 0 Male sterility protein MoaC PF01967.21 AAZ36394.1 - 6.9e-56 188.1 3.5 8e-56 187.9 3.5 1.0 1 0 0 1 1 1 1 MoaC family LysR_substrate PF03466.20 AAZ36395.1 - 1.7e-26 92.9 1.0 2.3e-26 92.5 1.0 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ36395.1 - 9.8e-17 60.7 0.8 2e-16 59.7 0.8 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_24 PF13412.6 AAZ36395.1 - 0.018 14.6 0.0 0.14 11.8 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding TPR_19 PF14559.6 AAZ36395.1 - 0.032 14.7 0.2 2.2 8.9 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat HTH_AsnC-type PF13404.6 AAZ36395.1 - 0.071 13.0 0.5 6.3 6.7 0.0 2.5 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Phage_TTP_13 PF16463.5 AAZ36395.1 - 0.12 11.9 0.0 0.29 10.7 0.0 1.6 2 0 0 2 2 2 0 Phage tail tube protein family TrkH PF02386.16 AAZ36396.1 - 2.4e-58 197.8 16.8 8.5e-57 192.7 16.8 2.0 1 1 0 1 1 1 1 Cation transport protein Peptidase_S24 PF00717.23 AAZ36397.1 - 2.9e-18 65.6 0.1 4.2e-18 65.1 0.1 1.2 1 0 0 1 1 1 1 Peptidase S24-like LexA_DNA_bind PF01726.16 AAZ36397.1 - 2.2e-15 56.2 0.2 3.1e-15 55.7 0.2 1.2 1 0 0 1 1 1 1 LexA DNA binding domain HTH_20 PF12840.7 AAZ36397.1 - 2.3e-05 24.4 0.0 4.5e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_11 PF08279.12 AAZ36397.1 - 9.9e-05 22.2 0.1 0.00017 21.5 0.1 1.4 1 0 0 1 1 1 1 HTH domain Rrf2 PF02082.20 AAZ36397.1 - 0.016 15.5 0.0 0.028 14.8 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator HTH_27 PF13463.6 AAZ36397.1 - 0.02 15.3 0.0 0.045 14.2 0.0 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain MarR_2 PF12802.7 AAZ36397.1 - 0.024 14.5 0.2 0.54 10.2 0.2 2.4 2 0 0 2 2 2 0 MarR family HTH_IclR PF09339.10 AAZ36397.1 - 0.025 14.4 0.1 0.25 11.2 0.0 2.6 3 0 0 3 3 3 0 IclR helix-turn-helix domain Dus PF01207.17 AAZ36398.1 - 1.9e-84 283.4 0.0 2.4e-84 283.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 AAZ36398.1 - 0.0028 17.2 0.0 0.16 11.4 0.0 2.2 2 0 0 2 2 2 2 Histidine biosynthesis protein TetR_C_2 PF08361.11 AAZ36399.1 - 7e-36 123.0 0.0 1.2e-35 122.2 0.0 1.4 1 0 0 1 1 1 1 MAATS-type transcriptional repressor, C-terminal region TetR_N PF00440.23 AAZ36399.1 - 8.2e-18 63.9 0.3 8.2e-18 63.9 0.3 1.7 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.6 AAZ36399.1 - 2.7e-07 30.8 1.7 3e-07 30.7 0.1 1.9 3 0 0 3 3 3 1 BetI-type transcriptional repressor, C-terminal TetR_C_11 PF16859.5 AAZ36399.1 - 0.0026 18.0 0.4 0.014 15.7 0.0 2.3 1 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain T_hemolysin PF12261.8 AAZ36399.1 - 0.053 13.3 0.1 0.074 12.8 0.1 1.2 1 0 0 1 1 1 0 Thermostable hemolysin TetR_C_24 PF17932.1 AAZ36399.1 - 0.071 13.4 0.0 0.19 12.0 0.0 1.8 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain LacI PF00356.21 AAZ36399.1 - 0.11 12.3 0.4 0.56 10.1 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family Molybdopterin PF00384.22 AAZ36400.1 - 2.4e-66 224.5 0.0 3e-66 224.2 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 AAZ36400.1 - 6.3e-22 77.7 0.0 1.7e-21 76.3 0.0 1.7 2 0 0 2 2 2 1 Molydopterin dinucleotide binding domain Molybdopterin_N PF18364.1 AAZ36400.1 - 1.5e-10 40.9 0.1 6.5e-10 38.9 0.1 2.2 1 0 0 1 1 1 1 Molybdopterin oxidoreductase N-terminal domain Aminotran_3 PF00202.21 AAZ36402.1 - 4.9e-51 173.7 0.1 7.6e-51 173.0 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 AAZ36402.1 - 0.0016 17.7 0.0 0.0027 17.0 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1_N PF03709.15 AAZ36402.1 - 0.13 12.6 0.0 7.1 7.0 0.0 2.4 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain DUF3509 PF12021.8 AAZ36403.1 - 3.5e-31 106.8 0.1 3.9e-31 106.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3509) CAP PF00188.26 AAZ36404.1 - 2.4e-18 67.2 0.3 6e-18 65.9 0.2 1.7 2 0 0 2 2 2 1 Cysteine-rich secretory protein family NMT1 PF09084.11 AAZ36405.1 - 5.4e-22 78.8 0.1 1.5e-21 77.4 0.0 1.7 1 1 0 1 1 1 1 NMT1/THI5 like OpuAC PF04069.12 AAZ36405.1 - 1.7e-18 67.1 3.6 2.6e-18 66.5 3.3 1.4 2 0 0 2 2 2 1 Substrate binding domain of ABC-type glycine betaine transport system NMT1_2 PF13379.6 AAZ36405.1 - 4.7e-13 49.4 2.2 8.7e-13 48.5 2.2 1.4 1 1 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.7 AAZ36405.1 - 6.1e-09 35.8 0.1 1.5e-08 34.6 0.1 1.6 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 AAZ36405.1 - 6e-06 25.9 0.3 0.0086 15.5 0.0 2.8 1 1 1 3 3 3 2 Bacterial extracellular solute-binding proteins, family 3 NMT1_3 PF16868.5 AAZ36405.1 - 0.027 13.9 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 NMT1-like family TRCF PF03461.15 AAZ36406.1 - 1.8e-28 98.8 0.0 1.1e-27 96.3 0.0 2.4 3 0 0 3 3 3 1 TRCF domain CarD_CdnL_TRCF PF02559.16 AAZ36406.1 - 2.2e-24 86.0 0.0 5.4e-24 84.7 0.0 1.7 1 0 0 1 1 1 1 CarD-like/TRCF domain UvrB_inter PF17757.1 AAZ36406.1 - 5.3e-22 77.8 0.0 1e-21 76.9 0.0 1.5 1 0 0 1 1 1 1 UvrB interaction domain DEAD PF00270.29 AAZ36406.1 - 7.9e-19 68.1 0.1 1.3e-18 67.3 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AAZ36406.1 - 4.9e-18 65.5 0.1 6.7e-17 61.8 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 AAZ36406.1 - 9.7e-09 35.5 0.0 2e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 AAZ36406.1 - 1.9e-05 23.5 0.0 2.6e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain UB2H PF14814.6 AAZ36406.1 - 0.00053 20.0 0.0 0.0018 18.3 0.0 1.9 1 0 0 1 1 1 1 Bifunctional transglycosylase second domain AroM PF07302.11 AAZ36406.1 - 0.0012 18.3 0.0 0.0035 16.8 0.0 1.7 1 0 0 1 1 1 1 AroM protein ERCC3_RAD25_C PF16203.5 AAZ36406.1 - 0.0025 17.0 0.0 0.0041 16.4 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 AAZ36406.1 - 0.02 15.2 0.6 0.29 11.4 0.6 2.6 1 1 0 1 1 1 0 AAA domain Big_3_4 PF13754.6 AAZ36407.1 - 0.029 14.1 0.0 0.037 13.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function HATPase_c PF02518.26 AAZ36408.1 - 5.6e-16 59.0 0.0 1.6e-15 57.6 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AAZ36408.1 - 0.00014 21.7 0.0 0.00031 20.6 0.0 1.6 1 0 0 1 1 1 1 GHKL domain HATPase_c_2 PF13581.6 AAZ36408.1 - 0.11 12.5 0.1 0.29 11.1 0.0 1.7 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain HCBP_related PF06594.11 AAZ36409.1 - 7.4e-22 77.0 15.4 0.0018 18.1 0.1 6.8 6 0 0 6 6 6 5 Haemolysin-type calcium binding protein related domain HemolysinCabind PF00353.19 AAZ36409.1 - 2.3e-15 56.2 91.4 0.00019 21.4 9.1 7.7 5 4 2 7 7 7 5 RTX calcium-binding nonapeptide repeat (4 copies) CbiC PF02570.15 AAZ36409.1 - 0.0088 15.7 0.5 0.015 15.0 0.5 1.2 1 0 0 1 1 1 1 Precorrin-8X methylmutase Vta1_C PF18097.1 AAZ36409.1 - 0.041 13.6 0.8 1.2e+02 2.4 0.0 4.1 4 0 0 4 4 4 0 Vta1 C-terminal domain BATS PF06968.13 AAZ36409.1 - 0.14 12.3 1.3 2.3e+02 2.0 0.0 4.5 5 0 0 5 5 5 0 Biotin and Thiamin Synthesis associated domain PS_pyruv_trans PF04230.13 AAZ36409.1 - 0.28 11.1 29.4 3.9 7.3 0.3 5.3 1 1 0 5 5 5 0 Polysaccharide pyruvyl transferase CPSase_sm_chain PF00988.22 AAZ36409.1 - 2.4 8.0 6.7 86 3.0 0.0 4.5 5 0 0 5 5 5 0 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_M22 PF00814.25 AAZ36410.1 - 1.1e-27 97.4 0.2 1.4e-27 97.1 0.2 1.1 1 0 0 1 1 1 1 Glycoprotease family SIS PF01380.22 AAZ36411.1 - 3e-60 201.8 0.2 1.9e-31 108.6 0.1 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 AAZ36411.1 - 1.2e-21 77.3 0.2 2.9e-21 76.1 0.2 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 AAZ36411.1 - 1e-15 57.7 0.0 1.7e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 AAZ36411.1 - 0.00027 19.9 0.0 0.00042 19.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II BshC PF10079.9 AAZ36411.1 - 0.2 10.4 0.0 0.33 9.6 0.0 1.3 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC AsnC_trans_reg PF01037.21 AAZ36412.1 - 1e-23 83.0 0.0 1.5e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 AAZ36412.1 - 2.4e-21 75.0 0.1 4.2e-21 74.2 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 AAZ36412.1 - 7.3e-18 64.1 0.6 1.2e-17 63.4 0.6 1.4 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_Crp_2 PF13545.6 AAZ36412.1 - 1.1e-08 34.9 0.1 2.3e-08 33.9 0.1 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain MarR PF01047.22 AAZ36412.1 - 1e-07 31.7 0.1 1.5e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 AAZ36412.1 - 1.3e-07 31.4 0.2 2.5e-07 30.5 0.2 1.5 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 AAZ36412.1 - 3.5e-05 23.8 0.0 6.9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Fe_dep_repress PF01325.19 AAZ36412.1 - 0.00048 20.3 0.0 0.00087 19.4 0.0 1.4 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_34 PF13601.6 AAZ36412.1 - 0.00056 20.0 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_IclR PF09339.10 AAZ36412.1 - 0.00076 19.2 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain Crp PF00325.20 AAZ36412.1 - 0.001 18.7 0.0 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, crp family HTH_11 PF08279.12 AAZ36412.1 - 0.0027 17.6 0.0 0.0049 16.8 0.0 1.4 1 0 0 1 1 1 1 HTH domain HTH_1 PF00126.27 AAZ36412.1 - 0.006 16.5 0.0 0.056 13.4 0.0 2.2 2 1 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_36 PF13730.6 AAZ36412.1 - 0.012 15.6 0.0 0.061 13.3 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain Phage_rep_O PF04492.13 AAZ36412.1 - 0.019 15.5 0.0 0.035 14.7 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage replication protein O Rrf2 PF02082.20 AAZ36412.1 - 0.026 14.9 0.0 0.051 13.9 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator SIMPL PF04402.14 AAZ36413.1 - 2.9e-25 89.9 0.9 3.4e-25 89.7 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF541) YbaB_DNA_bd PF02575.16 AAZ36413.1 - 0.34 11.2 2.8 0.97 9.7 0.4 2.5 3 0 0 3 3 3 0 YbaB/EbfC DNA-binding family PepSY_2 PF13670.6 AAZ36413.1 - 0.9 9.6 4.9 14 5.7 0.1 2.6 1 1 1 2 2 2 0 Peptidase propeptide and YPEB domain Lactonase PF10282.9 AAZ36414.1 - 9.3e-114 380.3 0.1 1.1e-113 380.1 0.1 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Cytochrom_D1 PF02239.16 AAZ36414.1 - 6.1e-05 21.7 0.3 0.8 8.2 0.0 3.9 1 1 2 4 4 4 3 Cytochrome D1 heme domain DUF1513 PF07433.11 AAZ36414.1 - 0.00063 18.9 0.0 0.073 12.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1513) SH3_6 PF12913.7 AAZ36414.1 - 0.0037 16.8 0.0 9.1 5.9 0.0 3.6 3 0 0 3 3 3 1 SH3 domain (SH3b1 type) SGL PF08450.12 AAZ36414.1 - 0.021 14.4 0.1 1.1e+02 2.3 0.0 3.1 1 1 1 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region PD40 PF07676.12 AAZ36414.1 - 0.051 13.5 0.0 42 4.2 0.0 3.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat tRNA-synt_2d PF01409.20 AAZ36415.1 - 2.8e-109 364.3 0.0 3.5e-109 364.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) Phe_tRNA-synt_N PF02912.18 AAZ36415.1 - 3.6e-27 94.1 0.9 6.1e-27 93.3 0.9 1.4 1 0 0 1 1 1 1 Aminoacyl tRNA synthetase class II, N-terminal domain tRNA_synthFbeta PF17759.1 AAZ36415.1 - 0.057 12.8 0.0 0.28 10.6 0.0 2.0 2 0 0 2 2 2 0 Phenylalanyl tRNA synthetase beta chain CLM domain Ribosomal_S6 PF01250.17 AAZ36416.1 - 1.7e-25 89.1 0.1 2.2e-25 88.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 TrkA_N PF02254.18 AAZ36417.1 - 5.7e-52 174.9 9.5 7.6e-27 93.9 0.2 3.2 5 0 0 5 5 4 2 TrkA-N domain TrkA_C PF02080.21 AAZ36417.1 - 4.2e-25 87.4 3.8 1.1e-11 44.4 0.1 3.2 3 0 0 3 3 3 2 TrkA-C domain NAD_binding_7 PF13241.6 AAZ36417.1 - 1.5e-11 44.6 0.2 0.0021 18.4 0.1 3.5 2 1 1 3 3 3 2 Putative NAD(P)-binding F420_oxidored PF03807.17 AAZ36417.1 - 5.3e-07 30.1 1.7 0.022 15.3 0.1 3.3 3 1 0 3 3 3 2 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 AAZ36417.1 - 1.8e-06 28.3 0.4 0.0021 18.3 0.1 2.9 3 0 0 3 3 3 2 Saccharopine dehydrogenase NADP binding domain Pyr_redox PF00070.27 AAZ36417.1 - 7.1e-06 26.5 1.5 0.43 11.2 0.1 3.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 AAZ36417.1 - 1.5e-05 25.1 0.1 0.014 15.4 0.0 2.8 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.14 AAZ36417.1 - 6e-05 22.4 0.9 0.023 14.0 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 AAZ36417.1 - 0.00014 21.3 0.2 0.51 9.6 0.0 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_Gly3P_dh_N PF01210.23 AAZ36417.1 - 0.00021 21.3 0.2 0.67 9.9 0.1 3.1 3 1 0 3 3 3 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 AAZ36417.1 - 0.00023 21.1 0.2 0.12 12.3 0.2 2.4 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AA_kinase PF00696.28 AAZ36417.1 - 0.00039 20.1 0.6 0.0023 17.6 0.2 2.2 2 1 1 3 3 3 1 Amino acid kinase family UDPG_MGDP_dh_N PF03721.14 AAZ36417.1 - 0.00073 19.2 1.5 0.0022 17.6 0.1 2.5 3 1 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 AAZ36417.1 - 0.00076 19.2 2.4 0.0068 16.1 0.2 2.8 2 2 1 3 3 3 1 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 AAZ36417.1 - 0.0043 17.2 0.1 2 8.5 0.0 3.1 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase DUF1188 PF06690.11 AAZ36417.1 - 0.0053 16.3 0.1 3.7 7.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1188) Gp_dh_N PF00044.24 AAZ36417.1 - 0.014 15.7 0.7 1.8 9.0 0.0 2.7 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 AAZ36417.1 - 0.017 14.5 0.2 1.6 8.1 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.6 AAZ36417.1 - 0.03 14.8 0.7 1.1 9.7 0.1 2.7 3 0 0 3 3 2 0 XdhC Rossmann domain ThiF PF00899.21 AAZ36417.1 - 0.42 9.9 1.8 1.4 8.2 0.7 2.1 2 0 0 2 2 2 0 ThiF family Gly-zipper_Omp PF13488.6 AAZ36418.1 - 0.001 19.0 26.2 0.0041 17.1 26.2 2.2 1 1 0 1 1 1 1 Glycine zipper DUF1269 PF06897.12 AAZ36418.1 - 0.029 14.6 6.0 0.072 13.4 6.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) Rick_17kDa_Anti PF05433.15 AAZ36418.1 - 0.34 10.8 30.5 2.5 8.1 9.1 3.0 2 0 0 2 2 2 0 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.6 AAZ36418.1 - 0.43 10.4 30.8 0.089 12.5 26.3 2.3 2 0 0 2 2 2 0 YMGG-like Gly-zipper DUF3482 PF11981.8 AAZ36418.1 - 3.9 6.8 7.7 5.8 6.2 7.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) TraT PF05818.12 AAZ36418.1 - 4.2 7.0 7.5 6.5 6.4 7.5 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Bacteriocin_IIc PF10439.9 AAZ36418.1 - 5.9 7.1 27.1 0.066 13.3 18.2 2.4 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide LysR_substrate PF03466.20 AAZ36420.1 - 2.7e-45 154.3 0.8 3.3e-45 154.0 0.8 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ36420.1 - 9e-22 76.8 1.2 1.4e-21 76.2 0.4 1.7 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family Response_reg PF00072.24 AAZ36421.1 - 7.7e-26 90.5 0.0 1.1e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAZ36421.1 - 5.2e-24 84.1 0.3 1.4e-23 82.7 0.0 1.8 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal DUF5100 PF17029.5 AAZ36421.1 - 0.2 11.5 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5100) DSBA PF01323.20 AAZ36422.1 - 1.2e-15 57.9 0.0 1.4e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_5 PF13743.6 AAZ36422.1 - 5.4e-12 45.8 0.0 8.3e-12 45.2 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_4 PF13462.6 AAZ36422.1 - 9.9e-05 22.6 0.0 0.00018 21.7 0.0 1.4 2 0 0 2 2 2 1 Thioredoxin TetR_N PF00440.23 AAZ36422.1 - 0.023 14.5 0.0 0.063 13.1 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family Thioredoxin PF00085.20 AAZ36422.1 - 0.06 13.4 0.0 3.6 7.6 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin GPP34 PF05719.11 AAZ36422.1 - 0.063 13.3 1.7 0.085 12.9 1.7 1.3 1 1 0 1 1 1 0 Golgi phosphoprotein 3 (GPP34) RNA_pol_Rpc34 PF05158.12 AAZ36422.1 - 0.22 10.9 0.0 0.24 10.7 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit DUF4096 PF13340.6 AAZ36423.1 - 5.8e-25 87.3 0.4 1.5e-24 86.0 0.4 1.8 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1 PF01609.21 AAZ36423.1 - 3.2e-14 53.1 0.0 5.7e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AAZ36423.1 - 7.2e-10 39.1 0.2 2.1e-09 37.6 0.2 1.9 1 0 0 1 1 1 1 Transposase DDE domain HTH_Tnp_Tc3_2 PF01498.18 AAZ36423.1 - 0.061 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Transposase MFS_1 PF07690.16 AAZ36424.1 - 3e-23 82.3 66.7 3.6e-13 49.2 33.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ATP-synt_ab PF00006.25 AAZ36425.1 - 1.5e-74 250.2 0.0 1.1e-73 247.4 0.0 2.0 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain T3SS_ATPase_C PF18269.1 AAZ36425.1 - 4.8e-20 71.2 0.0 7.5e-20 70.6 0.0 1.3 1 0 0 1 1 1 1 T3SS EscN ATPase C-terminal domain ATP-synt_ab_N PF02874.23 AAZ36425.1 - 0.0034 17.9 1.0 0.0061 17.1 0.2 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain ABC_tran PF00005.27 AAZ36425.1 - 0.083 13.4 0.1 0.17 12.4 0.1 1.5 1 0 0 1 1 1 0 ABC transporter ApbA PF02558.16 AAZ36426.1 - 5.5e-36 123.5 0.0 7.3e-36 123.1 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 AAZ36426.1 - 5.4e-29 100.9 0.0 9.8e-29 100.1 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DUF4810 PF16068.5 AAZ36426.1 - 0.074 13.6 0.2 3.2 8.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4810) 3HCDH_N PF02737.18 AAZ36426.1 - 0.077 12.9 0.7 0.12 12.3 0.1 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 AAZ36426.1 - 0.18 11.1 0.4 0.88 8.9 0.1 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Bac_export_2 PF01312.19 AAZ36427.1 - 9.1e-120 399.8 2.7 1e-119 399.6 2.7 1.0 1 0 0 1 1 1 1 FlhB HrpN YscU SpaS Family CBP_BcsG PF11658.8 AAZ36427.1 - 0.099 11.0 0.5 0.12 10.7 0.5 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG FCD PF07729.12 AAZ36428.1 - 2.5e-16 60.3 11.6 4.5e-16 59.4 11.6 1.4 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 AAZ36428.1 - 3e-14 52.4 0.0 6.9e-14 51.3 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_Crp_2 PF13545.6 AAZ36428.1 - 0.0068 16.4 0.0 0.031 14.2 0.0 2.2 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain Fe_dep_repress PF01325.19 AAZ36428.1 - 0.013 15.6 0.0 0.028 14.6 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain TrmB PF01978.19 AAZ36428.1 - 0.038 13.9 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB GH43_C2 PF17851.1 AAZ36428.1 - 0.065 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Beta xylosidase C-terminal Concanavalin A-like domain HTH_27 PF13463.6 AAZ36428.1 - 0.1 13.1 0.1 0.54 10.8 0.0 2.2 2 0 0 2 2 2 0 Winged helix DNA-binding domain Rrf2 PF02082.20 AAZ36428.1 - 0.12 12.8 0.0 0.5 10.8 0.0 2.1 1 0 0 1 1 1 0 Transcriptional regulator Rib_5-P_isom_A PF06026.14 AAZ36429.1 - 6.7e-58 195.1 0.0 8.4e-58 194.8 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Sugar-bind PF04198.13 AAZ36429.1 - 0.003 16.7 0.0 0.0059 15.8 0.0 1.4 1 0 0 1 1 1 1 Putative sugar-binding domain DeoRC PF00455.22 AAZ36429.1 - 0.0073 16.3 0.5 0.024 14.6 0.1 2.1 3 0 0 3 3 3 1 DeoR C terminal sensor domain FAA_hydrolase PF01557.18 AAZ36430.1 - 5.8e-51 173.3 0.0 6.4e-51 173.1 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family MoeA_N PF03453.17 AAZ36431.1 - 4.6e-44 149.9 0.3 1.1e-43 148.7 0.2 1.7 2 0 0 2 2 2 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 AAZ36431.1 - 5e-26 91.1 0.0 8.5e-26 90.3 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_C PF03454.15 AAZ36431.1 - 7.7e-17 61.2 0.0 2.2e-16 59.8 0.0 1.9 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) Bac_DNA_binding PF00216.21 AAZ36432.1 - 2e-28 98.4 0.0 2.3e-28 98.2 0.0 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 AAZ36432.1 - 2.3e-10 40.6 0.0 2.6e-10 40.5 0.0 1.0 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_bac_2 PF18175.1 AAZ36432.1 - 0.0013 18.5 0.0 0.002 18.0 0.0 1.2 1 0 0 1 1 1 1 CCDC81-like prokaryotic HU domain 2 HU-CCDC81_euk_1 PF14908.6 AAZ36432.1 - 0.0052 16.9 0.0 0.0059 16.7 0.0 1.1 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 1 HU-DNA_bdg PF14848.6 AAZ36432.1 - 0.03 14.3 0.0 0.11 12.5 0.0 1.8 1 1 0 1 1 1 0 DNA-binding domain HU-CCDC81_euk_2 PF18289.1 AAZ36432.1 - 0.036 14.2 0.0 0.056 13.6 0.0 1.3 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 2 HopW1-1 PF15457.6 AAZ36433.1 - 7.7e-166 551.1 14.9 1.4e-165 550.3 14.9 1.4 1 0 0 1 1 1 1 Type III T3SS secreted effector HopW1-1/HopPmaA Cucumopine_C PF18631.1 AAZ36433.1 - 0.024 14.6 0.0 0.11 12.4 0.0 2.1 3 0 0 3 3 3 0 Cucumopine synthase C-terminal helical bundle domain Rrf2 PF02082.20 AAZ36434.1 - 1.3e-28 99.1 0.2 3.7e-28 97.7 0.1 1.7 2 0 0 2 2 2 1 Transcriptional regulator MarR_2 PF12802.7 AAZ36434.1 - 0.0096 15.8 0.5 0.03 14.2 0.0 2.0 2 1 0 2 2 2 1 MarR family HrcA_DNA-bdg PF03444.15 AAZ36434.1 - 0.015 14.9 0.1 0.04 13.6 0.0 1.7 1 1 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding HTH_20 PF12840.7 AAZ36434.1 - 0.033 14.2 0.2 0.1 12.6 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain YjhX_toxin PF09857.9 AAZ36434.1 - 0.036 14.0 0.0 0.13 12.2 0.0 1.9 1 1 1 2 2 2 0 Putative toxin of bacterial toxin-antitoxin pair SMC_ScpB PF04079.16 AAZ36434.1 - 0.05 13.2 0.0 5.5 6.6 0.0 2.1 2 0 0 2 2 2 0 Segregation and condensation complex subunit ScpB HTH_47 PF16221.5 AAZ36434.1 - 0.069 12.7 0.0 0.21 11.2 0.0 1.8 2 0 0 2 2 2 0 winged helix-turn-helix HTH_AraC PF00165.23 AAZ36434.1 - 0.1 12.7 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_24 PF13412.6 AAZ36434.1 - 0.16 11.6 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF5407 PF17401.2 AAZ36434.1 - 0.18 12.1 1.5 0.54 10.6 0.1 2.4 3 0 0 3 3 3 0 Family of unknown function (DUF5407) ArsC PF03960.15 AAZ36435.1 - 7.7e-22 77.1 0.0 8.9e-22 76.9 0.0 1.1 1 0 0 1 1 1 1 ArsC family Syntaxin_2 PF14523.6 AAZ36435.1 - 0.12 12.8 0.0 0.15 12.4 0.0 1.1 1 0 0 1 1 1 0 Syntaxin-like protein CotJB PF12652.7 AAZ36435.1 - 0.13 12.5 0.0 0.26 11.5 0.0 1.5 2 0 0 2 2 2 0 CotJB protein MTS PF05175.14 AAZ36436.1 - 8.1e-54 181.7 0.0 7.5e-51 172.0 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_31 PF13847.6 AAZ36436.1 - 6.4e-11 42.3 0.0 1.4e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAZ36436.1 - 1.7e-08 35.0 0.1 4.3e-08 33.8 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 AAZ36436.1 - 1.9e-08 34.1 0.0 3.9e-08 33.0 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 AAZ36436.1 - 4e-07 30.7 0.0 1.3e-06 29.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 AAZ36436.1 - 8.4e-06 25.5 0.0 1.6e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_18 PF12847.7 AAZ36436.1 - 2.3e-05 24.3 0.0 4e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAZ36436.1 - 0.00015 22.3 0.0 0.00032 21.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 AAZ36436.1 - 0.00094 20.2 0.1 0.0058 17.6 0.1 2.1 2 1 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.18 AAZ36436.1 - 0.0079 15.9 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_23 PF13489.6 AAZ36436.1 - 0.015 15.1 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS_N PF08468.11 AAZ36436.1 - 0.018 15.1 0.0 0.13 12.3 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain N-terminal GidB PF02527.15 AAZ36436.1 - 0.082 12.2 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_4 PF02390.17 AAZ36436.1 - 0.099 12.1 0.0 0.2 11.1 0.0 1.6 1 1 0 1 1 1 0 Putative methyltransferase Molybdopterin PF00384.22 AAZ36437.1 - 1.6e-22 80.1 0.0 1.1e-11 44.4 0.0 2.0 2 0 0 2 2 2 2 Molybdopterin oxidoreductase DUF1127 PF06568.11 AAZ36437.1 - 0.072 12.8 0.1 0.23 11.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1127) Aldedh PF00171.22 AAZ36438.1 - 1.3e-163 544.8 0.1 1.5e-163 544.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 AAZ36438.1 - 0.00057 19.0 0.0 0.00088 18.4 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Response_reg PF00072.24 AAZ36439.1 - 1.3e-24 86.6 0.0 2.5e-24 85.6 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AAZ36439.1 - 1.8e-17 62.6 0.4 2.6e-17 62.1 0.4 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AAZ36439.1 - 1.7e-05 24.4 0.2 2.9e-05 23.6 0.2 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAZ36439.1 - 0.012 15.1 0.2 0.025 14.1 0.2 1.6 1 1 0 1 1 1 0 Sigma-70, region 4 HTH_23 PF13384.6 AAZ36439.1 - 0.025 14.4 0.1 0.049 13.4 0.1 1.4 1 0 0 1 1 1 0 Homeodomain-like domain FleQ PF06490.11 AAZ36439.1 - 0.047 14.1 0.0 0.073 13.5 0.0 1.3 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ DUF4031 PF13223.6 AAZ36439.1 - 0.057 13.6 0.0 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4031) PP_kinase_C_1 PF17941.1 AAZ36440.1 - 8.3e-71 236.9 0.0 1.5e-69 232.8 0.0 2.2 1 1 1 2 2 2 1 Polyphosphate kinase C-terminal domain 1 PP_kinase_C PF13090.6 AAZ36440.1 - 4.8e-67 224.7 0.0 2.4e-66 222.5 0.0 2.0 2 0 0 2 2 2 1 Polyphosphate kinase C-terminal domain 2 PP_kinase PF02503.17 AAZ36440.1 - 6.5e-66 221.8 0.0 1.3e-65 220.8 0.0 1.5 1 0 0 1 1 1 1 Polyphosphate kinase middle domain PP_kinase_N PF13089.6 AAZ36440.1 - 7.3e-35 119.5 0.2 1.7e-34 118.4 0.2 1.7 1 0 0 1 1 1 1 Polyphosphate kinase N-terminal domain PLDc_2 PF13091.6 AAZ36440.1 - 9.3e-13 48.2 0.0 1.6e-06 28.1 0.0 3.0 2 1 0 2 2 2 2 PLD-like domain AA_permease_2 PF13520.6 AAZ36441.1 - 1.6e-45 155.8 37.2 2e-45 155.4 37.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 AAZ36441.1 - 6.9e-28 97.5 35.1 9.6e-28 97.0 35.1 1.0 1 0 0 1 1 1 1 Amino acid permease Spore_permease PF03845.13 AAZ36441.1 - 2.9e-07 29.6 6.1 2.9e-07 29.6 6.1 2.5 2 1 0 2 2 2 2 Spore germination protein AA_permease_C PF13906.6 AAZ36441.1 - 0.00024 21.1 0.4 0.00024 21.1 0.4 4.1 4 0 0 4 4 4 1 C-terminus of AA_permease Nbl1_Borealin_N PF10444.9 AAZ36442.1 - 0.0097 15.5 0.6 1.7 8.3 0.0 2.4 2 0 0 2 2 2 2 Nbl1 / Borealin N terminal PCRF PF03462.18 AAZ36444.1 - 2e-74 249.7 0.6 2.8e-74 249.2 0.1 1.5 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 AAZ36444.1 - 3.6e-41 139.7 0.7 7.3e-41 138.8 0.7 1.5 1 0 0 1 1 1 1 RF-1 domain ABC_tran_CTD PF16326.5 AAZ36444.1 - 0.0022 18.2 1.9 0.3 11.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter C-terminal domain HR1 PF02185.16 AAZ36444.1 - 0.05 13.7 1.1 0.05 13.7 1.1 2.0 2 0 0 2 2 2 0 Hr1 repeat GntR PF00392.21 AAZ36445.1 - 5.1e-17 61.3 1.4 1e-16 60.3 1.4 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family FCD PF07729.12 AAZ36445.1 - 3.7e-13 50.0 0.5 6.9e-13 49.1 0.5 1.5 1 0 0 1 1 1 1 FCD domain HTH_20 PF12840.7 AAZ36445.1 - 0.00055 20.0 0.7 0.0011 19.0 0.7 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 AAZ36445.1 - 0.0011 18.9 0.2 0.0022 17.9 0.2 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Rrf2 PF02082.20 AAZ36445.1 - 0.005 17.2 0.0 0.0099 16.2 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator Fe_dep_repress PF01325.19 AAZ36445.1 - 0.012 15.8 0.0 0.034 14.4 0.0 1.7 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_11 PF08279.12 AAZ36445.1 - 0.025 14.5 0.0 0.058 13.3 0.0 1.7 1 0 0 1 1 1 0 HTH domain HTH_24 PF13412.6 AAZ36445.1 - 0.034 13.7 0.2 0.088 12.4 0.2 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF1631 PF07793.11 AAZ36446.1 - 7.7e-251 834.7 24.0 8.7e-251 834.5 24.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1631) MFS_1 PF07690.16 AAZ36447.1 - 4.3e-41 141.0 56.8 7.3e-32 110.7 43.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AAZ36447.1 - 2e-08 33.6 29.3 3.6e-06 26.1 6.8 3.2 2 1 1 3 3 3 3 Sugar (and other) transporter MtrF PF09472.10 AAZ36447.1 - 0.013 14.8 1.1 0.013 14.8 1.1 3.1 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) MASE3 PF17159.4 AAZ36447.1 - 2.3 7.8 20.4 0.49 10.0 10.6 3.1 1 1 2 3 3 3 0 Membrane-associated sensor domain DUF4293 PF14126.6 AAZ36447.1 - 3.5 7.9 5.9 0.78 10.0 1.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) OppC_N PF12911.7 AAZ36447.1 - 10 6.2 11.1 5 7.2 0.1 4.8 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C DNA_processg_A PF02481.15 AAZ36448.1 - 8.8e-76 253.8 0.0 1.1e-75 253.5 0.0 1.1 1 0 0 1 1 1 1 DNA recombination-mediator protein A DprA_WH PF17782.1 AAZ36448.1 - 1.2e-09 38.1 1.3 3.2e-09 36.8 1.3 1.7 1 0 0 1 1 1 1 DprA winged helix domain LDcluster4 PF18306.1 AAZ36448.1 - 1.2e-05 24.9 1.1 2.9e-05 23.7 1.1 1.6 1 1 0 1 1 1 1 SLOG cluster4 family Redoxin PF08534.10 AAZ36449.1 - 6e-28 97.4 0.1 7.1e-28 97.2 0.1 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 AAZ36449.1 - 3.9e-15 55.9 0.0 4.8e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family FAD_binding_2 PF00890.24 AAZ36450.1 - 1.2e-102 344.2 1.0 1.7e-102 343.6 0.5 1.5 2 0 0 2 2 2 1 FAD binding domain Succ_DH_flav_C PF02910.20 AAZ36450.1 - 4.6e-14 52.5 0.0 9.6e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 AAZ36450.1 - 2.8e-06 26.8 0.2 0.011 15.0 0.1 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AAZ36450.1 - 2.9e-06 27.1 3.7 6e-06 26.1 3.7 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 AAZ36450.1 - 0.0011 18.3 1.5 0.039 13.2 0.7 3.1 3 1 1 4 4 4 1 Thi4 family Lycopene_cycl PF05834.12 AAZ36450.1 - 0.045 12.8 0.4 0.07 12.2 0.4 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 AAZ36450.1 - 0.12 11.1 0.1 1.5 7.4 0.1 2.3 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.19 AAZ36450.1 - 0.16 11.2 0.7 0.33 10.1 0.4 1.7 2 0 0 2 2 2 0 FAD binding domain Ribosomal_S14 PF00253.21 AAZ36451.1 - 4.1e-24 84.1 1.0 5.9e-24 83.6 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e GSDH PF07995.11 AAZ36452.1 - 4e-12 46.1 0.4 3.3e-11 43.1 0.4 2.1 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase NHL PF01436.21 AAZ36452.1 - 7.3e-05 22.6 1.8 0.23 11.6 0.1 4.4 4 0 0 4 4 4 1 NHL repeat DUF5074 PF16819.5 AAZ36452.1 - 0.01 15.8 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5074) SGL PF08450.12 AAZ36452.1 - 0.014 15.0 0.3 0.1 12.2 0.0 2.1 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region Lactonase PF10282.9 AAZ36452.1 - 0.082 12.2 0.0 0.82 8.9 0.0 2.3 1 1 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Tail_tube PF10618.9 AAZ36453.1 - 3.7e-35 120.3 0.1 4.1e-35 120.2 0.1 1.0 1 0 0 1 1 1 1 Phage tail tube protein LysR_substrate PF03466.20 AAZ36454.1 - 7.1e-51 172.5 3.2 7.1e-51 172.5 3.2 1.4 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ36454.1 - 3.1e-19 68.7 0.1 8.4e-19 67.3 0.1 1.8 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family PBP_like PF12727.7 AAZ36454.1 - 0.0024 17.0 0.0 0.0065 15.6 0.0 1.5 1 1 0 1 1 1 1 PBP superfamily domain SBP_bac_11 PF13531.6 AAZ36454.1 - 0.037 13.8 0.3 3.9 7.1 0.3 2.7 1 1 0 1 1 1 0 Bacterial extracellular solute-binding protein Ribosomal_L4 PF00573.22 AAZ36455.1 - 1.7e-62 210.5 0.1 1.9e-62 210.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family ParE_toxin PF05016.15 AAZ36456.1 - 1.1e-12 48.3 0.1 1.3e-12 48.2 0.1 1.0 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE Bac_export_2 PF01312.19 AAZ36457.1 - 1.6e-77 261.0 0.3 1.9e-77 260.7 0.3 1.0 1 0 0 1 1 1 1 FlhB HrpN YscU SpaS Family T3SS_ExsE PF18286.1 AAZ36457.1 - 0.03 14.3 0.0 0.11 12.4 0.0 2.0 1 1 0 1 1 1 0 Type III secretion system ExsE TetR_C_3 PF08362.11 AAZ36458.1 - 2.3e-56 189.7 0.0 3.6e-56 189.1 0.0 1.3 1 0 0 1 1 1 1 YcdC-like protein, C-terminal region TetR_N PF00440.23 AAZ36458.1 - 1.1e-12 47.6 0.1 2.8e-12 46.2 0.1 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_29 PF17938.1 AAZ36458.1 - 0.0037 17.3 0.0 0.0061 16.6 0.0 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain CdiI_2 PF18593.1 AAZ36458.1 - 0.11 13.1 0.1 0.71 10.6 0.1 2.2 2 0 0 2 2 2 0 CdiI immunity protein BPD_transp_1 PF00528.22 AAZ36459.1 - 6.2e-25 88.0 16.6 6.2e-25 88.0 16.6 2.2 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component AIRS PF00586.24 AAZ36459.1 - 0.13 13.0 0.3 0.69 10.6 0.1 2.2 1 1 1 2 2 2 0 AIR synthase related protein, N-terminal domain TniB PF05621.11 AAZ36461.1 - 1.7e-67 226.5 0.1 2.1e-67 226.2 0.1 1.0 1 0 0 1 1 1 1 Bacterial TniB protein AAA_22 PF13401.6 AAZ36461.1 - 3.9e-17 62.8 0.0 5.6e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAZ36461.1 - 5.6e-05 23.6 0.0 0.0001 22.8 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain ATPase PF06745.13 AAZ36461.1 - 0.00015 21.2 0.0 0.21 10.9 0.1 2.1 2 0 0 2 2 2 2 KaiC G-alpha PF00503.20 AAZ36461.1 - 0.00015 21.0 0.0 0.00016 20.9 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Rad17 PF03215.15 AAZ36461.1 - 0.0011 18.9 0.0 0.0015 18.5 0.0 1.1 1 0 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 AAZ36461.1 - 0.0019 18.6 0.0 0.0048 17.3 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 AAZ36461.1 - 0.0052 17.0 0.0 0.01 16.1 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 AAZ36461.1 - 0.0073 16.3 0.0 0.026 14.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 AAZ36461.1 - 0.029 13.9 0.1 0.18 11.4 0.1 2.0 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 AAZ36461.1 - 0.034 13.5 0.1 0.088 12.1 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family NACHT PF05729.12 AAZ36461.1 - 0.04 13.8 0.0 0.058 13.3 0.0 1.2 1 0 0 1 1 1 0 NACHT domain CobA_CobO_BtuR PF02572.15 AAZ36461.1 - 0.05 13.9 0.2 0.078 13.2 0.2 1.4 1 1 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Ras PF00071.22 AAZ36461.1 - 0.058 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Ras family DEAD PF00270.29 AAZ36461.1 - 0.078 12.7 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase ATPase_2 PF01637.18 AAZ36461.1 - 0.096 12.6 0.1 0.22 11.4 0.1 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 AAZ36461.1 - 0.12 12.2 0.0 0.34 10.7 0.0 1.8 1 1 0 1 1 1 0 P-loop containing region of AAA domain DnaB_C PF03796.15 AAZ36461.1 - 0.16 11.3 0.1 0.31 10.3 0.1 1.4 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Abhydrolase_6 PF12697.7 AAZ36462.1 - 1.6e-09 38.7 8.6 2e-09 38.4 8.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AAZ36462.1 - 1.3e-07 31.5 0.0 3.2e-07 30.3 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AAZ36462.1 - 0.0026 17.1 0.0 0.032 13.5 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 AAZ36462.1 - 0.011 15.8 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain DLH PF01738.18 AAZ36462.1 - 0.037 13.6 0.2 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 AAZ36462.1 - 0.11 12.3 0.0 0.57 9.9 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family Hypoth_Ymh PF09509.10 AAZ36464.1 - 2.2e-25 88.9 0.0 1.4e-24 86.3 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (Hypoth_ymh) HATPase_c_3 PF13589.6 AAZ36464.1 - 1.3e-13 50.9 0.1 2.5e-13 50.0 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1082 PF06449.11 AAZ36465.1 - 0.099 12.5 0.9 0.18 11.6 0.2 1.9 1 1 0 1 1 1 0 Mitochondrial domain of unknown function (DUF1082) Trep_Strep PF09605.10 AAZ36465.1 - 7.7 6.4 19.2 19 5.2 0.7 3.0 1 1 1 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) LPAM_1 PF08139.12 AAZ36466.1 - 0.077 13.5 0.6 0.11 13.1 0.6 1.1 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site DUF3050 PF11251.8 AAZ36467.1 - 6.2e-90 300.9 0.2 8.1e-90 300.5 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3050) Haem_oxygenas_2 PF14518.6 AAZ36467.1 - 2.7e-08 33.8 3.4 3.4e-08 33.5 3.4 1.2 1 0 0 1 1 1 1 Iron-containing redox enzyme Glyco_hydro_92N PF17678.1 AAZ36467.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 92 N-terminal domain Condensation PF00668.20 AAZ36468.1 - 5.4e-277 918.7 3.3 2e-103 346.5 0.0 3.2 3 0 0 3 3 3 3 Condensation domain AMP-binding PF00501.28 AAZ36468.1 - 5.8e-186 618.2 0.0 3e-99 332.5 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme PP-binding PF00550.25 AAZ36468.1 - 4.3e-30 103.9 1.3 8.1e-14 51.7 0.3 3.2 2 0 0 2 2 2 2 Phosphopantetheine attachment site Thioesterase PF00975.20 AAZ36468.1 - 2.4e-28 99.8 0.4 3.5e-27 96.0 0.0 3.0 3 0 0 3 3 3 1 Thioesterase domain AMP-binding_C PF13193.6 AAZ36468.1 - 1.9e-25 89.7 0.1 1.3e-13 51.7 0.0 3.3 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain AATase PF07247.12 AAZ36468.1 - 0.00091 17.9 0.0 0.16 10.5 0.0 3.1 3 0 0 3 3 3 1 Alcohol acetyltransferase Abhydrolase_6 PF12697.7 AAZ36468.1 - 0.0014 19.3 0.1 0.0014 19.3 0.1 5.3 4 2 0 5 5 5 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAZ36468.1 - 0.036 13.3 0.0 0.095 11.9 0.0 1.7 1 0 0 1 1 1 0 Serine aminopeptidase, S33 TPR_6 PF13174.6 AAZ36469.1 - 2.7e-16 59.0 5.3 0.00069 20.1 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TolA_bind_tri PF16331.5 AAZ36469.1 - 3e-12 46.4 4.7 6.9e-12 45.3 4.7 1.6 1 0 0 1 1 1 1 TolA binding protein trimerisation TPR_14 PF13428.6 AAZ36469.1 - 3.2e-10 40.0 3.9 0.0065 17.2 0.0 4.2 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 AAZ36469.1 - 1.1e-09 38.7 6.9 2.7e-09 37.5 1.2 3.5 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 AAZ36469.1 - 3.3e-09 36.2 3.2 0.017 15.2 0.4 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat YfiO PF13525.6 AAZ36469.1 - 5e-09 36.2 2.0 5e-09 36.2 2.0 2.0 2 1 0 2 2 2 1 Outer membrane lipoprotein TPR_12 PF13424.6 AAZ36469.1 - 7.2e-07 29.4 1.3 2e-05 24.8 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 AAZ36469.1 - 1.2e-06 29.0 11.0 1.4e-05 25.5 0.7 3.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_21 PF09976.9 AAZ36469.1 - 0.00018 21.3 1.0 0.00018 21.3 1.0 2.5 2 2 0 2 2 2 1 Tetratricopeptide repeat-like domain TPR_18 PF13512.6 AAZ36469.1 - 0.00019 21.6 2.4 0.0005 20.2 0.4 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_MalT PF17874.1 AAZ36469.1 - 0.0069 15.8 1.7 0.046 13.1 0.1 2.2 2 0 0 2 2 2 1 MalT-like TPR region TPR_17 PF13431.6 AAZ36469.1 - 0.028 14.8 0.1 12 6.6 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 AAZ36469.1 - 0.041 14.1 2.1 8 7.0 0.0 4.1 5 1 0 5 5 4 0 Tetratricopeptide repeat SKA1 PF07160.12 AAZ36469.1 - 0.11 12.3 0.1 0.17 11.7 0.1 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 COG2 PF06148.11 AAZ36469.1 - 0.17 11.9 0.5 0.32 11.1 0.5 1.4 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 SlyX PF04102.12 AAZ36469.1 - 2 9.1 7.4 6.8 7.4 4.7 2.4 2 0 0 2 2 2 0 SlyX Trp_halogenase PF04820.14 AAZ36470.1 - 1e-28 100.4 0.0 9.6e-15 54.4 0.0 2.1 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 AAZ36470.1 - 1.3e-19 70.7 0.0 1.7e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 AAZ36470.1 - 1.8e-09 37.6 0.4 0.0019 17.9 0.0 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 AAZ36470.1 - 2.6e-09 36.9 0.3 1.2e-08 34.7 0.3 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 AAZ36470.1 - 4.9e-08 32.5 0.0 3.6e-05 23.1 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AAZ36470.1 - 1e-06 28.8 0.0 3.5e-06 27.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 AAZ36470.1 - 2.4e-05 23.2 0.0 5.8e-05 22.0 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 AAZ36470.1 - 0.00027 20.2 0.0 0.00039 19.6 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 AAZ36470.1 - 0.0003 20.0 0.1 0.00067 18.9 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 AAZ36470.1 - 0.00058 20.4 0.0 0.041 14.5 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAZ36470.1 - 0.0018 17.6 0.1 0.0047 16.2 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 AAZ36470.1 - 0.0041 16.2 0.1 0.22 10.5 0.1 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 AAZ36470.1 - 0.0041 16.4 0.0 0.0068 15.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family ApbA PF02558.16 AAZ36470.1 - 0.018 14.7 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA SE PF08491.10 AAZ36470.1 - 0.025 13.7 0.0 0.035 13.1 0.0 1.1 1 0 0 1 1 1 0 Squalene epoxidase AlaDh_PNT_C PF01262.21 AAZ36470.1 - 0.043 13.1 0.0 0.072 12.4 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 AAZ36470.1 - 0.073 12.2 0.0 3.5 6.7 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.18 AAZ36470.1 - 0.1 12.8 0.1 0.19 12.0 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain LPD26 PF18842.1 AAZ36470.1 - 0.12 12.4 0.2 0.26 11.3 0.2 1.5 1 0 0 1 1 1 0 Large polyvalent protein associated domain 26 Shikimate_DH PF01488.20 AAZ36470.1 - 0.16 12.1 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase SmpA_OmlA PF04355.13 AAZ36471.1 - 0.019 14.7 0.2 0.062 13.1 0.1 1.9 2 0 0 2 2 2 0 SmpA / OmlA family HAD_2 PF13419.6 AAZ36472.1 - 3.9e-35 121.5 0.0 4.8e-35 121.2 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAZ36472.1 - 1.1e-22 81.4 0.0 1.4e-22 81.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AAZ36472.1 - 1.1e-14 55.2 0.0 1.7e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AAZ36472.1 - 2.2e-10 40.4 0.0 4.3e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 AAZ36472.1 - 3.9e-05 23.7 0.1 0.00045 20.3 0.1 2.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AAZ36472.1 - 0.0011 18.7 0.1 12 5.5 0.0 3.1 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 AAZ36472.1 - 0.0018 18.2 0.0 1.3 8.9 0.1 3.0 2 1 0 2 2 2 1 Acid Phosphatase NIF PF03031.18 AAZ36472.1 - 0.0044 16.8 0.0 0.11 12.3 0.0 2.2 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase S6PP PF05116.13 AAZ36472.1 - 0.047 13.2 0.2 3.7 7.0 0.0 2.9 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase DUF1967 PF09269.11 AAZ36472.1 - 0.056 13.4 0.0 1.6 8.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) PNK3P PF08645.11 AAZ36472.1 - 0.09 12.5 0.2 18 5.0 0.1 2.8 3 0 0 3 3 3 0 Polynucleotide kinase 3 phosphatase Put_Phosphatase PF06888.12 AAZ36472.1 - 0.14 11.5 0.0 25 4.2 0.0 2.7 3 0 0 3 3 3 0 Putative Phosphatase Polysacc_deac_2 PF04748.13 AAZ36474.1 - 2.2e-75 252.5 0.1 2.5e-75 252.3 0.1 1.0 1 0 0 1 1 1 1 Divergent polysaccharide deacetylase DUF3107 PF11305.8 AAZ36474.1 - 0.07 13.4 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3107) MafB19-deam PF14437.6 AAZ36475.1 - 1.1e-30 106.2 0.0 1.4e-30 105.9 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 AAZ36475.1 - 1.4e-28 98.7 0.0 2e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.6 AAZ36475.1 - 1.6e-06 28.3 0.1 4.4e-06 26.8 0.1 1.7 1 1 1 2 2 2 1 Bd3614-like deaminase APOBEC3 PF18771.1 AAZ36475.1 - 0.0028 17.8 0.0 0.005 17.0 0.0 1.4 1 0 0 1 1 1 1 APOBEC3 SNAD4 PF18750.1 AAZ36475.1 - 0.0094 16.1 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 Inv-AAD PF18785.1 AAZ36475.1 - 0.046 13.6 0.1 0.22 11.4 0.1 2.1 1 1 0 1 1 1 0 Invertebrate-AID/APOBEC-deaminase APOBEC2 PF18772.1 AAZ36475.1 - 0.05 13.7 0.0 0.073 13.1 0.0 1.2 1 0 0 1 1 1 0 APOBEC2 NAD2 PF18782.1 AAZ36475.1 - 0.075 13.1 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 APOBEC_N PF08210.11 AAZ36475.1 - 0.083 12.8 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain NAD1 PF18778.1 AAZ36475.1 - 0.24 11.5 0.0 0.35 10.9 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 Lyase_1 PF00206.20 AAZ36476.1 - 3.5e-66 223.7 0.0 5e-66 223.2 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 AAZ36476.1 - 1.4e-20 73.6 0.9 3.9e-20 72.2 0.4 2.0 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus ASL_C PF08328.11 AAZ36476.1 - 0.00099 19.2 0.0 0.002 18.2 0.0 1.5 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminal ASL_C2 PF14698.6 AAZ36476.1 - 0.029 15.1 0.1 0.12 13.2 0.1 2.0 1 0 0 1 1 1 0 Argininosuccinate lyase C-terminal PSK_trans_fac PF07704.11 AAZ36476.1 - 0.21 12.4 2.8 0.21 12.3 0.5 2.3 2 0 0 2 2 2 0 Rv0623-like transcription factor OprF PF05736.11 AAZ36478.1 - 1.3e-86 289.1 6.7 1.9e-86 288.5 6.7 1.2 1 0 0 1 1 1 1 OprF membrane domain OmpA PF00691.20 AAZ36478.1 - 1.1e-23 83.4 0.2 2.8e-23 82.1 0.1 1.7 2 0 0 2 2 2 1 OmpA family OMP_b-brl PF13505.6 AAZ36478.1 - 1.3e-10 41.7 13.6 2.2e-10 41.0 12.7 1.7 1 1 0 1 1 1 1 Outer membrane protein beta-barrel domain TSP_3 PF02412.18 AAZ36478.1 - 0.079 12.7 11.2 0.34 10.6 8.9 2.5 1 1 1 2 2 2 0 Thrombospondin type 3 repeat ATP-grasp_2 PF08442.10 AAZ36479.1 - 2.2e-80 269.0 0.0 3.1e-80 268.5 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 AAZ36479.1 - 3.3e-24 85.4 3.9 6.7e-24 84.4 3.9 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 AAZ36479.1 - 1.2e-12 47.8 0.7 2.5e-12 46.7 0.1 1.9 2 1 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 AAZ36479.1 - 4.2e-05 23.4 0.0 0.00011 22.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp PF02222.22 AAZ36479.1 - 0.013 15.1 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain OKR_DC_1_N PF03709.15 AAZ36479.1 - 0.042 14.1 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain SBP_bac_11 PF13531.6 AAZ36480.1 - 7.9e-41 140.3 0.1 9.7e-41 140.0 0.1 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AAZ36480.1 - 8.8e-09 35.1 0.5 4.5e-08 32.8 0.1 1.9 1 1 1 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 AAZ36480.1 - 4.3e-05 23.5 1.9 6.6e-05 22.9 1.9 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein PBP_like PF12727.7 AAZ36480.1 - 0.16 11.0 0.0 0.37 9.9 0.0 1.7 1 1 0 1 1 1 0 PBP superfamily domain Phage_integrase PF00589.22 AAZ36481.1 - 8.7e-05 22.4 0.0 0.00063 19.6 0.0 2.4 2 1 0 2 2 2 1 Phage integrase family VF530 PF09905.9 AAZ36482.1 - 3.7e-34 116.7 0.0 6.8e-34 115.8 0.0 1.4 1 0 0 1 1 1 1 DNA-binding protein VF530 Lipase_GDSL_2 PF13472.6 AAZ36483.1 - 2.4e-25 89.9 0.0 2.8e-25 89.8 0.0 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 AAZ36483.1 - 1.8e-13 50.9 0.0 2.1e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase OSK PF17182.4 AAZ36483.1 - 0.2 10.9 0.0 0.25 10.5 0.0 1.1 1 0 0 1 1 1 0 OSK domain DIM PF08194.12 AAZ36483.1 - 0.2 11.9 0.4 0.37 11.0 0.4 1.5 1 0 0 1 1 1 0 DIM protein DUF2066 PF09839.9 AAZ36484.1 - 1.5e-67 227.4 3.0 2.2e-67 226.8 3.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2066) ALS_ss_C PF10369.9 AAZ36484.1 - 0.017 15.4 0.0 0.076 13.2 0.0 1.9 2 0 0 2 2 2 0 Small subunit of acetolactate synthase DUF4428 PF14471.6 AAZ36485.1 - 0.054 13.4 1.1 7.1 6.6 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) zf-C3HC PF07967.13 AAZ36485.1 - 0.46 10.5 3.5 6.3 6.8 0.5 2.2 1 1 1 2 2 2 0 C3HC zinc finger-like MinE PF03776.14 AAZ36486.1 - 7.1e-26 90.0 0.1 8.3e-26 89.8 0.1 1.1 1 0 0 1 1 1 1 Septum formation topological specificity factor MinE MlaE PF02405.16 AAZ36487.1 - 7.1e-76 254.6 15.9 8.7e-76 254.3 15.9 1.1 1 0 0 1 1 1 1 Permease MlaE Bro-N PF02498.17 AAZ36488.1 - 1.8e-05 25.3 0.0 3e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 BRO family, N-terminal domain Thiolase_N PF00108.23 AAZ36489.1 - 1.5e-80 270.3 0.4 2.1e-80 269.9 0.4 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 AAZ36489.1 - 1.9e-42 143.8 0.9 1.9e-41 140.6 0.5 2.4 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.10 AAZ36489.1 - 0.024 14.8 0.1 0.079 13.1 0.1 1.9 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal TauE PF01925.19 AAZ36490.1 - 5.7e-41 140.7 43.6 6.6e-41 140.5 43.6 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE Phage_holin_3_6 PF07332.11 AAZ36490.1 - 0.73 9.9 0.0 0.73 9.9 0.0 4.3 2 2 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III adh_short_C2 PF13561.6 AAZ36491.1 - 2e-69 233.7 2.4 2.3e-69 233.5 2.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAZ36491.1 - 9.7e-52 175.3 0.5 1.2e-51 175.0 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAZ36491.1 - 2e-07 31.1 1.5 3.7e-07 30.2 1.5 1.4 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 AAZ36491.1 - 0.0024 17.8 0.3 0.0039 17.1 0.3 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 AAZ36491.1 - 0.029 14.5 0.2 0.045 13.8 0.2 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ADH_zinc_N PF00107.26 AAZ36491.1 - 0.086 12.8 0.8 0.16 11.9 0.8 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 AAZ36491.1 - 0.09 12.3 0.2 0.76 9.3 0.0 2.0 1 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ACR_tran PF00873.19 AAZ36492.1 - 0 1269.4 11.6 0 1269.2 11.6 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AAZ36492.1 - 1.5e-10 40.6 38.5 2.1e-07 30.2 18.0 2.7 2 1 0 2 2 2 2 MMPL family SecD_SecF PF02355.16 AAZ36492.1 - 2.5e-05 23.8 14.3 2.5e-05 23.8 14.3 3.1 4 0 0 4 4 4 2 Protein export membrane protein DUF4407 PF14362.6 AAZ36492.1 - 1.3 8.3 5.0 4 6.7 5.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) tRNA-synt_1e PF01406.19 AAZ36493.1 - 1.7e-135 451.2 0.0 2.2e-135 450.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DALR_2 PF09190.11 AAZ36493.1 - 1.1e-21 77.1 0.3 3.5e-21 75.4 0.3 2.0 1 0 0 1 1 1 1 DALR domain tRNA-synt_1g PF09334.11 AAZ36493.1 - 2.5e-12 46.3 0.3 4.3e-06 25.7 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 AAZ36493.1 - 8.3e-07 27.6 0.0 7.2e-06 24.5 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 AAZ36493.1 - 4.5e-06 25.8 0.0 9.1e-05 21.5 0.0 2.3 3 0 0 3 3 3 1 tRNA synthetases class I (K) Cir_Bir_Yir PF06022.11 AAZ36493.1 - 0.16 11.4 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 Plasmodium variant antigen protein Cir/Yir/Bir Glycos_transf_2 PF00535.26 AAZ36494.1 - 1.4e-19 70.5 0.0 2.4e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAZ36494.1 - 6.4e-17 62.2 0.0 1.1e-16 61.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 AAZ36494.1 - 0.0068 15.9 0.0 0.71 9.3 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_tranf_2_5 PF13712.6 AAZ36494.1 - 0.082 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family AlgF PF11182.8 AAZ36495.1 - 4.6e-77 257.9 1.0 5.5e-77 257.6 1.0 1.0 1 0 0 1 1 1 1 Alginate O-acetyl transferase AlgF LTD PF00932.19 AAZ36495.1 - 0.023 15.0 1.0 0.078 13.3 0.9 2.0 1 1 1 2 2 2 0 Lamin Tail Domain VWA PF00092.28 AAZ36495.1 - 0.06 13.6 0.1 0.075 13.3 0.1 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain HTH_38 PF13936.6 AAZ36496.1 - 2.7e-06 27.0 0.2 5.3e-06 26.1 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_7 PF02796.15 AAZ36496.1 - 4.1e-06 26.8 0.2 7.4e-06 25.9 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase Sigma70_r4_2 PF08281.12 AAZ36496.1 - 7.6e-06 25.5 0.2 1.2e-05 24.9 0.2 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 AAZ36496.1 - 2.5e-05 24.0 0.1 5.5e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 AAZ36496.1 - 5.6e-05 23.1 0.1 0.00018 21.4 0.0 1.9 2 0 0 2 2 1 1 Winged helix-turn helix HTH_28 PF13518.6 AAZ36496.1 - 0.00019 21.5 0.1 0.00042 20.4 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_10 PF04967.12 AAZ36496.1 - 0.00044 20.0 0.0 0.00088 19.0 0.0 1.5 1 0 0 1 1 1 1 HTH DNA binding domain HTH_8 PF02954.19 AAZ36496.1 - 0.0005 19.8 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family HTH_11 PF08279.12 AAZ36496.1 - 0.00057 19.8 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 HTH domain HTH_30 PF13556.6 AAZ36496.1 - 0.00076 19.2 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain GerE PF00196.19 AAZ36496.1 - 0.0021 17.6 0.0 0.0034 16.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_36 PF13730.6 AAZ36496.1 - 0.0037 17.2 0.0 0.0069 16.3 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain NUMOD1 PF07453.13 AAZ36496.1 - 0.0049 17.1 0.0 0.0093 16.2 0.0 1.5 1 0 0 1 1 1 1 NUMOD1 domain HTH_22 PF13309.6 AAZ36496.1 - 0.0074 16.3 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 HTH domain TnsD PF15978.5 AAZ36496.1 - 0.0092 15.0 0.0 0.011 14.8 0.0 1.1 1 0 0 1 1 1 1 Tn7-like transposition protein D Sigma70_r4 PF04545.16 AAZ36496.1 - 0.011 15.3 0.2 0.022 14.3 0.2 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_24 PF13412.6 AAZ36496.1 - 0.011 15.3 0.1 0.023 14.3 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_3 PF01381.22 AAZ36496.1 - 0.012 15.6 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix Phage_NinH PF06322.11 AAZ36496.1 - 0.017 15.0 0.1 0.034 14.0 0.1 1.5 1 0 0 1 1 1 0 Phage NinH protein HTH_17 PF12728.7 AAZ36496.1 - 0.022 15.0 0.0 0.049 13.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Terminase_5 PF06056.12 AAZ36496.1 - 0.027 14.3 0.0 0.061 13.2 0.0 1.6 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_IclR PF09339.10 AAZ36496.1 - 0.028 14.2 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain DUF2089 PF09862.9 AAZ36496.1 - 0.029 14.4 0.0 0.047 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) Sigma70_ECF PF07638.11 AAZ36496.1 - 0.032 14.1 0.1 0.043 13.7 0.1 1.2 1 0 0 1 1 1 0 ECF sigma factor HTH_Tnp_1 PF01527.20 AAZ36496.1 - 0.036 14.4 0.0 0.065 13.6 0.0 1.5 1 0 0 1 1 1 0 Transposase MerR PF00376.23 AAZ36496.1 - 0.084 12.7 0.3 0.45 10.3 0.0 2.1 2 0 0 2 2 2 0 MerR family regulatory protein DUF903 PF06004.12 AAZ36497.1 - 4.5e-22 77.7 1.4 5.2e-22 77.5 1.4 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF903) FlbD PF06289.11 AAZ36497.1 - 0.062 12.9 0.0 5.4 6.7 0.0 2.1 2 0 0 2 2 2 0 Flagellar and Swarming motility proteins HgmA PF04209.13 AAZ36498.1 - 1.7e-201 669.5 0.0 1.9e-201 669.3 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase DNA_pol3_beta_2 PF02767.16 AAZ36500.1 - 1.1e-49 167.5 0.2 1.9e-39 134.4 0.0 3.1 4 0 0 4 4 4 2 DNA polymerase III beta subunit, central domain DNA_pol3_beta PF00712.19 AAZ36500.1 - 4.1e-48 162.5 0.8 1.1e-41 141.8 0.0 3.1 3 0 0 3 3 3 3 DNA polymerase III beta subunit, N-terminal domain DNA_pol3_beta_3 PF02768.15 AAZ36500.1 - 1.3e-45 154.1 0.3 4.3e-42 142.8 0.1 2.3 2 0 0 2 2 2 2 DNA polymerase III beta subunit, C-terminal domain TubC_N PF18563.1 AAZ36500.1 - 0.044 13.8 0.5 0.82 9.7 0.0 3.3 5 0 0 5 5 5 0 TubC N-terminal docking domain HSP20 PF00011.21 AAZ36500.1 - 0.1 12.8 0.0 1 9.6 0.0 2.4 2 0 0 2 2 2 0 Hsp20/alpha crystallin family RNase_T PF00929.24 AAZ36501.1 - 1.2e-15 58.5 0.0 2.9e-15 57.2 0.0 1.6 1 1 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 AAZ36501.1 - 4.4e-09 36.5 0.2 7.5e-09 35.8 0.2 1.4 1 1 0 1 1 1 1 3' exoribonuclease, RNase T-like MscL PF01741.18 AAZ36502.1 - 1.2e-44 151.5 0.5 1.4e-44 151.3 0.5 1.0 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL DUF3487 PF11990.8 AAZ36502.1 - 0.0052 16.7 4.9 0.45 10.4 0.7 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3487) Glyoxalase PF00903.25 AAZ36503.1 - 1.1e-05 25.6 0.1 9e-05 22.7 0.1 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 AAZ36503.1 - 0.022 15.0 0.0 0.23 11.7 0.0 2.0 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 AAZ36503.1 - 0.032 14.2 0.0 3 7.8 0.1 2.3 2 1 0 2 2 2 0 Glyoxalase-like domain MHB PF16525.5 AAZ36506.1 - 0.019 15.2 0.1 0.046 14.0 0.1 1.7 2 0 0 2 2 2 0 Haemophore, haem-binding TP_methylase PF00590.20 AAZ36508.1 - 4.6e-33 115.0 0.1 5.6e-33 114.7 0.1 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Acetyltransf_11 PF13720.6 AAZ36509.1 - 1.1e-26 93.1 0.0 1.6e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Hexapep PF00132.24 AAZ36509.1 - 2.3e-21 74.6 19.6 1.7e-07 30.7 0.7 5.7 3 2 4 7 7 7 4 Bacterial transferase hexapeptide (six repeats) DUF2407_C PF13373.6 AAZ36509.1 - 0.016 15.4 0.0 0.027 14.6 0.0 1.3 1 0 0 1 1 1 0 DUF2407 C-terminal domain DUF1248 PF06852.12 AAZ36509.1 - 0.13 11.8 0.0 0.49 9.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1248) Hexapep_2 PF14602.6 AAZ36509.1 - 0.15 11.8 14.7 0.29 10.9 2.3 4.5 5 1 1 6 6 6 0 Hexapeptide repeat of succinyl-transferase MMR_HSR1 PF01926.23 AAZ36510.1 - 1.7e-16 60.3 0.0 2.3e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 AAZ36510.1 - 0.00026 20.9 0.0 0.046 13.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 AAZ36510.1 - 0.0014 18.2 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 AAZ36510.1 - 0.016 15.2 0.1 0.17 12.0 0.0 2.1 1 1 1 2 2 2 0 Dynamin family SRPRB PF09439.10 AAZ36510.1 - 0.062 12.7 0.0 0.12 11.8 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ZnuA PF01297.17 AAZ36511.1 - 1.7e-55 188.2 0.1 2e-55 188.0 0.1 1.0 1 0 0 1 1 1 1 Zinc-uptake complex component A periplasmic DUF4845 PF16137.5 AAZ36512.1 - 5.5e-22 78.4 0.9 6.7e-22 78.1 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4845) N_methyl PF07963.12 AAZ36512.1 - 0.0033 16.9 0.2 0.0044 16.5 0.2 1.2 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif DUF2536 PF10750.9 AAZ36512.1 - 0.11 12.5 0.2 8.1 6.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2536) HTH_Tnp_1 PF01527.20 AAZ36513.1 - 5.6e-18 65.0 1.4 7.9e-18 64.6 1.4 1.2 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.6 AAZ36513.1 - 0.00015 21.7 0.2 0.00031 20.7 0.0 1.6 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 AAZ36513.1 - 0.0003 20.8 0.1 0.00058 19.9 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AAZ36513.1 - 0.00035 20.3 1.4 0.0011 18.7 0.1 2.2 2 1 0 2 2 2 1 Homeodomain-like domain KASH_CCD PF14662.6 AAZ36513.1 - 0.006 16.4 3.0 0.0068 16.3 3.0 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH TSC22 PF01166.18 AAZ36513.1 - 0.0078 16.5 2.3 0.01 16.1 1.0 1.7 2 0 0 2 2 2 1 TSC-22/dip/bun family FlxA PF14282.6 AAZ36513.1 - 0.019 14.9 1.6 0.029 14.4 1.6 1.3 1 0 0 1 1 1 0 FlxA-like protein DivIC PF04977.15 AAZ36513.1 - 0.036 13.8 4.3 0.062 13.1 4.3 1.4 1 1 0 1 1 1 0 Septum formation initiator Shugoshin_N PF07558.11 AAZ36513.1 - 0.041 13.8 0.6 0.072 13.0 0.6 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region BLOC1_2 PF10046.9 AAZ36513.1 - 0.045 14.1 0.4 0.066 13.5 0.4 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3287 PF11690.8 AAZ36513.1 - 0.046 13.4 2.1 0.24 11.1 0.6 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF3287) M PF02370.16 AAZ36513.1 - 0.057 14.0 0.8 0.23 12.1 0.3 2.2 1 1 1 2 2 2 0 M protein repeat DUF4140 PF13600.6 AAZ36513.1 - 0.097 13.1 3.3 0.21 12.0 3.3 1.7 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) ZapB PF06005.12 AAZ36513.1 - 0.42 11.1 7.6 3.5 8.1 4.2 2.2 1 1 2 3 3 3 0 Cell division protein ZapB ABC_tran_CTD PF16326.5 AAZ36513.1 - 0.54 10.5 7.5 0.12 12.6 4.3 1.7 2 0 0 2 2 2 0 ABC transporter C-terminal domain Acyl-CoA_dh_N PF02771.16 AAZ36514.1 - 7e-16 58.9 0.1 1.6e-15 57.7 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 AAZ36514.1 - 7e-15 55.5 2.0 7e-15 55.5 2.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 AAZ36514.1 - 1.8e-08 34.5 0.0 3.5e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 AAZ36514.1 - 4.8e-05 23.6 0.3 0.00013 22.2 0.3 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cys_rich_CPXG PF14255.6 AAZ36515.1 - 4.4e-23 80.9 3.6 4.9e-23 80.8 3.6 1.0 1 0 0 1 1 1 1 Cysteine-rich CPXCG zf-Di19 PF05605.12 AAZ36515.1 - 0.0083 16.4 1.2 0.17 12.2 0.1 2.1 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C3HC4_3 PF13920.6 AAZ36515.1 - 0.018 14.9 3.4 0.83 9.6 0.0 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF2256 PF10013.9 AAZ36515.1 - 0.033 14.3 0.7 8.2 6.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) Sgf11 PF08209.11 AAZ36515.1 - 0.27 10.8 2.8 4.9 6.8 0.0 2.1 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Lar_restr_allev PF14354.6 AAZ36515.1 - 3.6 8.0 7.1 39 4.7 7.0 2.0 1 1 1 2 2 2 0 Restriction alleviation protein Lar Rad50_zn_hook PF04423.14 AAZ36515.1 - 6.6 6.6 6.6 12 5.9 1.8 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif DUF1275 PF06912.11 AAZ36516.1 - 0.32 10.9 12.8 0.83 9.5 2.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1275) Wzy_C PF04932.15 AAZ36516.1 - 0.43 10.2 4.7 0.61 9.7 4.7 1.5 1 1 0 1 1 1 0 O-Antigen ligase EamA PF00892.20 AAZ36517.1 - 1.3e-29 103.1 41.4 2.8e-17 63.2 16.8 2.3 2 1 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 AAZ36517.1 - 0.058 12.3 6.7 0.11 11.4 4.9 2.1 2 1 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like MtN3_slv PF03083.16 AAZ36517.1 - 1.6 8.8 8.2 1.9 8.6 4.3 2.6 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Lyase_8 PF02278.18 AAZ36518.1 - 1.3e-55 188.6 0.5 5.3e-55 186.7 0.9 1.7 2 0 0 2 2 2 1 Polysaccharide lyase family 8, super-sandwich domain GbpA_2 PF18416.1 AAZ36518.1 - 1.3e-23 83.2 0.0 1.7e-11 44.3 0.0 2.7 2 0 0 2 2 2 2 N-acetylglucosamine binding protein domain 2 Lyase_8_N PF08124.11 AAZ36518.1 - 9.3e-18 64.2 0.2 1.7e-17 63.3 0.2 1.3 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Lyase_8_C PF02884.17 AAZ36518.1 - 0.00011 22.6 0.0 0.024 15.1 0.0 2.8 2 0 0 2 2 2 1 Polysaccharide lyase family 8, C-terminal beta-sandwich domain tRNA_edit PF04073.15 AAZ36519.1 - 5.8e-24 84.5 0.2 6.8e-24 84.3 0.2 1.1 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain Ribosomal_S3_C PF00189.20 AAZ36520.1 - 3e-42 143.0 2.2 1.2e-41 141.1 1.8 2.0 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 AAZ36520.1 - 4.5e-22 77.7 1.2 4.5e-22 77.7 1.2 2.0 2 0 0 2 2 2 1 KH domain KH_4 PF13083.6 AAZ36520.1 - 0.014 15.3 0.1 0.037 13.9 0.1 1.7 1 1 0 1 1 1 0 KH domain DNA_pol3_a_NI PF14480.6 AAZ36520.1 - 0.074 13.1 0.0 0.27 11.2 0.0 1.9 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus I ALGX PF16822.5 AAZ36521.1 - 3.3e-82 276.2 0.0 4.7e-82 275.7 0.0 1.2 1 0 0 1 1 1 1 SGNH hydrolase-like domain, acetyltransferase AlgX CBM_26 PF16824.5 AAZ36521.1 - 2.1e-64 215.5 0.0 3.2e-64 214.9 0.0 1.3 1 0 0 1 1 1 1 C-terminal carbohydrate-binding module BATS PF06968.13 AAZ36522.1 - 4.1e-19 68.5 0.0 1.1e-18 67.2 0.0 1.7 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 AAZ36522.1 - 1.1e-13 51.9 0.0 1.8e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily VWA_2 PF13519.6 AAZ36523.1 - 2.2e-12 47.6 0.0 3.1e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 AAZ36523.1 - 6.6e-07 29.7 0.0 8.4e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 AAZ36523.1 - 4.5e-05 23.4 0.0 6.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain GTP_EFTU PF00009.27 AAZ36524.1 - 6.8e-47 159.5 0.0 1.2e-46 158.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RF3_C PF16658.5 AAZ36524.1 - 5.5e-46 155.6 0.0 9.7e-46 154.8 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain GTP_EFTU_D2 PF03144.25 AAZ36524.1 - 1e-10 41.8 0.0 2.2e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 AAZ36524.1 - 8.4e-07 29.0 0.0 1.7e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 AAZ36524.1 - 0.00023 21.2 0.0 0.00059 19.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 AAZ36524.1 - 0.049 13.1 0.1 0.64 9.4 0.1 2.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AsnC_trans_reg PF01037.21 AAZ36525.1 - 8.6e-15 54.5 0.0 1.5e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_AsnC-type PF13404.6 AAZ36525.1 - 4.9e-14 51.9 4.4 4.9e-14 51.9 4.4 2.0 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 AAZ36525.1 - 3.4e-09 36.1 1.0 6.2e-09 35.3 1.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 AAZ36525.1 - 5.6e-05 23.0 0.8 0.00013 21.8 0.8 1.6 1 0 0 1 1 1 1 MarR family HTH_50 PF18024.1 AAZ36525.1 - 0.00022 20.7 0.1 0.00044 19.8 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 AAZ36525.1 - 0.0021 18.2 0.2 0.0049 17.0 0.2 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_30 PF13556.6 AAZ36525.1 - 0.0031 17.3 0.2 0.0058 16.4 0.2 1.4 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_Crp_2 PF13545.6 AAZ36525.1 - 0.0038 17.2 0.5 0.0079 16.2 0.5 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_IclR PF09339.10 AAZ36525.1 - 0.0052 16.6 0.9 0.013 15.2 0.9 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_38 PF13936.6 AAZ36525.1 - 0.009 15.8 0.4 0.015 15.0 0.4 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_20 PF12840.7 AAZ36525.1 - 0.017 15.2 1.0 0.045 13.8 0.2 2.0 3 0 0 3 3 2 0 Helix-turn-helix domain HTH_29 PF13551.6 AAZ36525.1 - 0.023 14.7 0.7 0.23 11.5 0.2 2.2 2 1 0 2 2 2 0 Winged helix-turn helix GntR PF00392.21 AAZ36525.1 - 0.024 14.3 1.4 0.051 13.2 0.4 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_11 PF08279.12 AAZ36525.1 - 0.039 13.9 0.4 0.072 13.0 0.4 1.4 1 0 0 1 1 1 0 HTH domain MarR PF01047.22 AAZ36525.1 - 0.041 13.8 0.2 0.1 12.5 0.2 1.6 1 0 0 1 1 1 0 MarR family Fe_dep_repress PF01325.19 AAZ36525.1 - 0.042 14.0 0.3 0.28 11.4 0.1 2.1 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain HTH_10 PF04967.12 AAZ36525.1 - 0.049 13.4 1.0 0.066 13.0 0.2 1.7 2 0 0 2 2 1 0 HTH DNA binding domain HTH_8 PF02954.19 AAZ36525.1 - 0.081 12.7 1.7 0.18 11.6 1.7 1.6 1 1 0 1 1 1 0 Bacterial regulatory protein, Fis family STALD PF18185.1 AAZ36525.1 - 0.086 12.2 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Sir2- and TIR-associating SLOG family LZ_Tnp_IS481 PF13011.6 AAZ36525.1 - 0.12 13.0 0.4 8.4 7.0 0.2 2.2 1 1 0 2 2 2 0 leucine-zipper of insertion element IS481 HTH_23 PF13384.6 AAZ36525.1 - 0.15 11.9 0.3 0.15 11.9 0.3 1.8 2 0 0 2 2 2 0 Homeodomain-like domain LysR_substrate PF03466.20 AAZ36526.1 - 1.1e-33 116.4 3.4 1.6e-33 115.8 3.4 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ36526.1 - 4.2e-18 65.0 2.6 9.3e-18 63.9 2.6 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_5 PF01022.20 AAZ36526.1 - 0.008 16.0 0.1 0.021 14.7 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_30 PF13556.6 AAZ36526.1 - 0.012 15.4 0.1 0.024 14.4 0.1 1.5 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain P22_Cro PF14549.6 AAZ36526.1 - 0.088 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro HTH_8 PF02954.19 AAZ36526.1 - 0.16 11.7 0.4 0.36 10.7 0.0 1.8 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family DctM PF06808.12 AAZ36527.1 - 9.5e-110 367.3 56.4 1.1e-109 367.1 56.4 1.0 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporter, DctM component PspA_IM30 PF04012.12 AAZ36528.1 - 3.2e-45 154.4 27.5 3.9e-45 154.1 27.5 1.0 1 0 0 1 1 1 1 PspA/IM30 family DUF3584 PF12128.8 AAZ36528.1 - 0.0015 16.2 19.9 0.0017 16.0 19.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Fez1 PF06818.15 AAZ36528.1 - 0.0063 17.0 14.3 0.011 16.2 14.3 1.4 1 0 0 1 1 1 1 Fez1 DASH_Spc19 PF08287.11 AAZ36528.1 - 0.092 12.6 19.1 0.47 10.3 2.0 2.9 1 1 2 3 3 3 0 Spc19 DUF848 PF05852.11 AAZ36528.1 - 0.16 12.1 9.1 0.1 12.7 6.2 2.0 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF5082 PF16888.5 AAZ36528.1 - 0.2 11.9 10.9 0.048 13.9 6.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) VPS38 PF17649.1 AAZ36528.1 - 0.33 9.8 2.7 0.43 9.4 2.7 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting 38 XhlA PF10779.9 AAZ36528.1 - 0.38 11.0 9.1 4.1 7.7 0.6 3.5 3 0 0 3 3 3 0 Haemolysin XhlA Golgin_A5 PF09787.9 AAZ36528.1 - 1 8.7 15.9 1.8 8.0 15.5 1.5 1 1 0 1 1 1 0 Golgin subfamily A member 5 EMP24_GP25L PF01105.24 AAZ36528.1 - 2.2 8.2 5.4 5.9 6.8 5.4 1.9 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD V_ATPase_I PF01496.19 AAZ36528.1 - 2.3 6.1 6.4 2.9 5.7 6.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fib_alpha PF08702.10 AAZ36528.1 - 4.6 7.4 8.2 3.1 8.0 6.1 1.8 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family P4Ha_N PF08336.11 AAZ36528.1 - 5.1 7.1 9.8 0.34 10.9 3.0 2.3 3 0 0 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region FliD_N PF02465.18 AAZ36528.1 - 6 7.6 12.3 1.2 9.9 3.5 2.9 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 N-terminus DUF3138 PF11336.8 AAZ36528.1 - 6.8 5.2 12.3 4.5 5.8 11.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3138) BPD_transp_1 PF00528.22 AAZ36529.1 - 1.5e-15 57.4 19.6 1.5e-15 57.4 19.6 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component adh_short PF00106.25 AAZ36530.1 - 1.5e-25 89.8 0.0 1.9e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAZ36530.1 - 1.6e-22 80.2 0.0 1.9e-22 80.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAZ36530.1 - 1.7e-08 34.6 0.6 2.3e-08 34.2 0.6 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 AAZ36530.1 - 0.00052 20.0 0.4 0.00078 19.4 0.4 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 AAZ36530.1 - 0.00092 18.7 0.0 0.002 17.7 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AAZ36530.1 - 0.077 12.4 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Eno-Rase_NADH_b PF12242.8 AAZ36530.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase GTP_cyclohydroI PF01227.22 AAZ36531.1 - 1.5e-75 252.5 0.4 1.8e-75 252.3 0.4 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I MbtH PF03621.13 AAZ36532.1 - 1e-24 85.7 0.1 1.4e-24 85.2 0.1 1.3 1 0 0 1 1 1 1 MbtH-like protein AAA_3 PF07726.11 AAZ36534.1 - 7.5e-64 213.5 0.1 1.3e-63 212.7 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 AAZ36534.1 - 2.5e-20 72.1 0.2 7e-20 70.6 0.2 1.8 1 0 0 1 1 1 1 AAA lid domain AAA_5 PF07728.14 AAZ36534.1 - 5.3e-11 42.7 0.0 1.1e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM PF00493.23 AAZ36534.1 - 7.5e-06 25.2 0.0 1.1e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain Sigma54_activat PF00158.26 AAZ36534.1 - 0.00097 18.9 0.0 0.0044 16.7 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain RuvB_N PF05496.12 AAZ36534.1 - 0.005 16.6 0.3 0.089 12.5 0.1 2.5 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 AAZ36534.1 - 0.0051 17.2 0.0 0.082 13.3 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 AAZ36534.1 - 0.0092 15.4 0.3 0.53 9.6 0.1 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 AAZ36534.1 - 0.046 14.1 0.1 0.094 13.1 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 AAZ36534.1 - 0.088 12.5 0.1 0.24 11.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain Bmp PF02608.14 AAZ36535.1 - 2.5e-55 187.6 0.1 3.6e-55 187.1 0.1 1.1 1 0 0 1 1 1 1 ABC transporter substrate-binding protein PnrA-like Peripla_BP_6 PF13458.6 AAZ36535.1 - 3.9e-07 30.0 1.4 0.00045 20.0 0.3 2.3 2 0 0 2 2 2 2 Periplasmic binding protein BPD_transp_1 PF00528.22 AAZ36536.1 - 5.9e-26 91.3 14.1 5.9e-26 91.3 14.1 1.7 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component NDUF_B12 PF08122.12 AAZ36536.1 - 0.62 10.2 2.7 9.1 6.4 0.2 3.0 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family Phage_holin_2_1 PF04971.12 AAZ36536.1 - 3.9 7.5 4.7 1.6 8.8 0.1 2.5 2 0 0 2 2 2 0 Bacteriophage P21 holin S LysR_substrate PF03466.20 AAZ36537.1 - 2.1e-34 118.7 0.0 2.7e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ36537.1 - 9.1e-22 76.8 0.2 1.7e-21 75.9 0.2 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family DHDPS PF00701.22 AAZ36539.1 - 1.2e-25 89.8 0.0 1.4e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Abhydrolase_1 PF00561.20 AAZ36540.1 - 5.6e-13 49.1 0.0 1.4e-12 47.8 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAZ36540.1 - 1.1e-06 29.5 0.0 1.4e-06 29.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAZ36540.1 - 3.5e-06 26.4 0.0 1.4e-05 24.5 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PhoPQ_related PF10142.9 AAZ36540.1 - 0.016 13.9 0.1 0.02 13.5 0.1 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein BAAT_C PF08840.11 AAZ36540.1 - 0.026 14.4 0.0 0.042 13.8 0.0 1.4 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_4 PF08386.10 AAZ36540.1 - 0.037 14.1 0.0 0.099 12.8 0.0 1.7 1 0 0 1 1 1 0 TAP-like protein FSH1 PF03959.13 AAZ36540.1 - 0.039 13.6 0.0 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 Serine hydrolase (FSH1) CbtA_toxin PF06755.12 AAZ36540.1 - 0.086 12.9 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 CbtA_toxin of type IV toxin-antitoxin system Transgly PF00912.22 AAZ36542.1 - 3.1e-57 192.9 0.0 4.9e-57 192.2 0.0 1.2 1 0 0 1 1 1 1 Transglycosylase UB2H PF14814.6 AAZ36542.1 - 7.6e-23 80.4 0.0 1.5e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 Bifunctional transglycosylase second domain Transpeptidase PF00905.22 AAZ36542.1 - 1.2e-17 64.1 0.0 9.3e-17 61.2 0.0 2.0 1 1 0 1 1 1 1 Penicillin binding protein transpeptidase domain UvrB_inter PF17757.1 AAZ36542.1 - 5.5e-07 29.7 0.0 2e-06 27.9 0.0 1.9 2 0 0 2 2 2 1 UvrB interaction domain PBP1_TM PF14812.6 AAZ36542.1 - 0.51 10.7 0.1 0.51 10.7 0.1 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal E1-E2_ATPase PF00122.20 AAZ36543.1 - 3.1e-57 193.0 1.0 3.1e-57 193.0 1.0 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 AAZ36543.1 - 2.8e-40 138.9 1.7 4.8e-40 138.1 1.7 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AAZ36543.1 - 3e-06 27.2 1.4 0.027 14.2 0.6 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HMA PF00403.26 AAZ36543.1 - 0.00051 20.4 0.0 0.0012 19.3 0.0 1.7 1 0 0 1 1 1 1 Heavy-metal-associated domain HAD PF12710.7 AAZ36543.1 - 0.00084 19.8 0.1 0.0047 17.4 0.1 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase CSD PF00313.22 AAZ36544.1 - 4.1e-29 100.2 1.9 4.5e-29 100.1 1.9 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 AAZ36544.1 - 0.0092 15.6 0.2 0.015 15.0 0.2 1.4 1 0 0 1 1 1 1 Ribonuclease B OB domain CusF_Ec PF11604.8 AAZ36544.1 - 0.067 13.2 0.2 0.094 12.7 0.2 1.3 1 0 0 1 1 1 0 Copper binding periplasmic protein CusF OEP PF02321.18 AAZ36545.1 - 2.4e-41 141.6 30.9 5.9e-22 78.4 8.3 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein Ni_hydr_CYTB PF01292.20 AAZ36546.1 - 4e-24 85.2 9.1 5e-24 84.9 9.1 1.1 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 Acyl_transf_3 PF01757.22 AAZ36546.1 - 0.00047 19.3 4.4 0.00061 18.9 4.3 1.2 1 1 0 1 1 1 1 Acyltransferase family Sdh_cyt PF01127.22 AAZ36546.1 - 0.021 14.9 4.2 0.66 10.0 0.2 2.4 2 0 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF4079 PF13301.6 AAZ36546.1 - 0.031 14.4 8.0 0.24 11.5 4.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) DUF1211 PF06736.11 AAZ36546.1 - 0.074 13.5 2.1 0.3 11.6 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1211) DUF2339 PF10101.9 AAZ36546.1 - 0.12 10.9 8.3 0.18 10.3 8.3 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2339) Oxidored_q3 PF00499.20 AAZ36546.1 - 1 9.1 8.1 65 3.2 7.4 2.6 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 SBP_bac_5 PF00496.22 AAZ36547.1 - 9.9e-35 120.2 0.7 1.2e-34 119.9 0.7 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle Sigma70_r2 PF04542.14 AAZ36548.1 - 4.8e-22 77.5 0.1 8.1e-22 76.8 0.1 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r3 PF04539.16 AAZ36548.1 - 7.4e-22 77.2 0.6 1.1e-20 73.6 0.3 2.5 2 0 0 2 2 2 1 Sigma-70 region 3 Sigma70_r4 PF04545.16 AAZ36548.1 - 3.6e-16 58.4 3.9 7.3e-15 54.2 3.1 2.7 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r1_2 PF00140.20 AAZ36548.1 - 2.3e-11 43.5 0.0 4.9e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Sigma-70 factor, region 1.2 Sigma70_r4_2 PF08281.12 AAZ36548.1 - 0.0023 17.5 0.0 0.48 10.1 0.1 2.7 2 1 0 2 2 2 2 Sigma-70, region 4 LON_substr_bdg PF02190.16 AAZ36549.1 - 6e-24 85.1 0.0 7.7e-23 81.5 0.0 1.9 1 1 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain PDH PF02153.17 AAZ36549.1 - 0.16 10.9 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase ThiS PF02597.20 AAZ36550.1 - 1.1e-15 58.0 0.2 1.3e-15 57.8 0.2 1.1 1 0 0 1 1 1 1 ThiS family RNase_II_C_S1 PF18614.1 AAZ36550.1 - 0.088 12.8 1.0 0.25 11.3 0.2 1.9 2 0 0 2 2 2 0 RNase II-type exonuclease C-terminal S1 domain Fer2_4 PF13510.6 AAZ36550.1 - 0.098 12.7 0.0 0.15 12.1 0.0 1.4 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Cupin_2 PF07883.11 AAZ36551.1 - 2.4e-18 65.6 0.1 3.9e-18 64.9 0.1 1.4 1 0 0 1 1 1 1 Cupin domain HTH_3 PF01381.22 AAZ36551.1 - 9.3e-12 44.8 0.2 1.4e-11 44.2 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 AAZ36551.1 - 3.6e-09 36.8 0.1 6.1e-09 36.1 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 AAZ36551.1 - 1.8e-08 34.2 0.0 3.1e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain AraC_binding PF02311.19 AAZ36551.1 - 0.00013 21.9 0.1 0.00024 21.0 0.1 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain HTH_26 PF13443.6 AAZ36551.1 - 0.00064 20.1 0.0 0.00091 19.6 0.0 1.2 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain Cupin_1 PF00190.22 AAZ36551.1 - 0.0049 16.5 0.0 0.0073 15.9 0.0 1.3 1 0 0 1 1 1 1 Cupin HTH_37 PF13744.6 AAZ36551.1 - 0.0092 15.9 0.1 0.014 15.3 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain CENP-C_C PF11699.8 AAZ36551.1 - 0.0093 16.2 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like MannoseP_isomer PF01050.18 AAZ36551.1 - 0.012 15.5 0.0 0.018 14.9 0.0 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase HTH_24 PF13412.6 AAZ36551.1 - 0.02 14.4 0.1 0.037 13.6 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_25 PF13413.6 AAZ36551.1 - 0.076 12.9 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain LacI PF00356.21 AAZ36551.1 - 0.14 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family Cupin_3 PF05899.12 AAZ36551.1 - 0.21 11.3 0.2 0.46 10.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF861) GHL10 PF02638.15 AAZ36552.1 - 6.7e-90 301.3 6.0 7.9e-90 301.1 6.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase-like 10 Melibiase PF02065.18 AAZ36552.1 - 0.0096 14.9 0.1 0.016 14.2 0.1 1.3 1 0 0 1 1 1 1 Melibiase LysE PF01810.18 AAZ36553.1 - 1.4e-23 83.3 16.3 1.7e-23 83.1 16.3 1.1 1 0 0 1 1 1 1 LysE type translocator TRIC PF05197.13 AAZ36553.1 - 0.068 12.7 3.8 0.1 12.1 3.8 1.3 1 0 0 1 1 1 0 TRIC channel DUF5325 PF17259.2 AAZ36553.1 - 9.8 6.1 7.7 14 5.6 1.6 3.0 2 1 0 2 2 2 0 Family of unknown function (DUF5325) CoA_trans PF01144.23 AAZ36554.1 - 3e-75 252.3 0.6 3.4e-75 252.2 0.6 1.0 1 0 0 1 1 1 1 Coenzyme A transferase DUF294_C PF10335.9 AAZ36555.1 - 3.3e-44 150.2 2.4 6.2e-44 149.3 2.4 1.5 1 0 0 1 1 1 1 Putative nucleotidyltransferase substrate binding domain DUF294 PF03445.13 AAZ36555.1 - 4.5e-43 146.4 0.2 1.7e-42 144.5 0.0 2.0 2 0 0 2 2 2 1 Putative nucleotidyltransferase DUF294 CBS PF00571.28 AAZ36555.1 - 5e-20 71.7 0.9 7.2e-11 42.4 0.0 3.3 4 0 0 4 4 4 2 CBS domain cNMP_binding PF00027.29 AAZ36555.1 - 2.3e-10 40.4 0.0 5.9e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain GlnD_UR_UTase PF08335.11 AAZ36555.1 - 0.032 14.3 1.8 0.067 13.3 0.3 2.2 2 0 0 2 2 2 0 GlnD PII-uridylyltransferase Response_reg PF00072.24 AAZ36556.1 - 2.2e-26 92.2 0.0 8.5e-26 90.3 0.0 1.8 2 0 0 2 2 2 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAZ36556.1 - 5e-23 81.0 0.1 1.2e-22 79.7 0.0 1.7 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal MarR_2 PF12802.7 AAZ36556.1 - 0.016 15.1 0.1 0.061 13.2 0.0 2.0 1 1 1 2 2 2 0 MarR family Peptidase_A24 PF01478.18 AAZ36557.1 - 1.2e-08 35.4 9.5 1.9e-08 34.7 9.5 1.3 1 0 0 1 1 1 1 Type IV leader peptidase family DHBP_synthase PF00926.19 AAZ36558.1 - 8.5e-83 276.6 1.6 1.1e-82 276.2 1.6 1.1 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase GTP_cyclohydro2 PF00925.20 AAZ36558.1 - 2.1e-31 108.7 0.0 4e-31 107.8 0.0 1.5 1 0 0 1 1 1 1 GTP cyclohydrolase II NUDIX PF00293.28 AAZ36560.1 - 2.8e-14 53.3 0.0 3.7e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Nudix_hydro PF18290.1 AAZ36560.1 - 6.1e-13 48.6 0.0 1.1e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Nudix hydrolase domain BPD_transp_1 PF00528.22 AAZ36561.1 - 1.1e-30 106.7 5.2 1.1e-30 106.7 5.2 2.7 3 0 0 3 3 3 2 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 AAZ36561.1 - 4e-10 39.5 1.7 4e-10 39.5 1.7 2.7 2 0 0 2 2 2 1 N-terminal TM domain of oligopeptide transport permease C Acyl_transf_3 PF01757.22 AAZ36562.1 - 2.2e-32 112.4 33.6 2.2e-32 112.4 33.6 1.5 2 0 0 2 2 2 1 Acyltransferase family Myelin_PLP PF01275.19 AAZ36562.1 - 8.6 6.1 7.8 5.5 6.8 0.5 3.0 2 1 0 3 3 3 0 Myelin proteolipid protein (PLP or lipophilin) DUF2427 PF10348.9 AAZ36562.1 - 9.8 6.0 8.5 2.3 8.1 0.3 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF2427) EAL PF00563.20 AAZ36563.1 - 9.1e-76 254.5 0.0 4.5e-75 252.2 0.0 2.1 2 0 0 2 2 2 1 EAL domain GGDEF PF00990.21 AAZ36563.1 - 9.9e-45 152.2 0.0 2.3e-44 151.0 0.0 1.7 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_9 PF13426.7 AAZ36563.1 - 1.9e-07 31.3 0.0 4.4e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 AAZ36563.1 - 5.3e-07 29.9 0.0 1.5e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 PAS fold GAF_2 PF13185.6 AAZ36563.1 - 2.2e-06 28.0 0.1 5.6e-05 23.5 0.1 2.8 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.6 AAZ36563.1 - 0.0029 18.0 0.4 0.01 16.2 0.0 2.1 2 0 0 2 2 2 1 GAF domain LapD_MoxY_N PF16448.5 AAZ36563.1 - 0.035 14.0 0.0 0.088 12.7 0.0 1.7 1 0 0 1 1 1 0 LapD/MoxY periplasmic domain DUF4261 PF14080.6 AAZ36563.1 - 0.059 13.5 0.0 0.94 9.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4261) PHO4 PF01384.20 AAZ36564.1 - 2.9e-87 292.9 9.5 3.7e-87 292.5 9.5 1.1 1 0 0 1 1 1 1 Phosphate transporter family Flavi_M PF01004.19 AAZ36564.1 - 0.055 13.2 0.3 7.2 6.5 0.0 2.6 2 0 0 2 2 2 0 Flavivirus envelope glycoprotein M DUF3015 PF11220.8 AAZ36565.1 - 1.1e-56 190.6 1.7 1.3e-56 190.4 1.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3015) Isochorismatase PF00857.20 AAZ36566.1 - 2.8e-23 83.0 0.0 8.1e-23 81.5 0.0 1.6 1 1 0 1 1 1 1 Isochorismatase family HD_4 PF13328.6 AAZ36567.1 - 5.4e-51 172.4 5.7 1.4e-50 171.1 5.7 1.7 1 0 0 1 1 1 1 HD domain RelA_SpoT PF04607.17 AAZ36567.1 - 1.7e-36 125.0 0.0 3.8e-36 123.9 0.0 1.6 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins TGS PF02824.21 AAZ36567.1 - 2.1e-18 66.1 0.0 4.9e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 TGS domain ACT_4 PF13291.6 AAZ36567.1 - 2.2e-15 57.0 2.0 7.3e-15 55.3 2.0 1.9 1 0 0 1 1 1 1 ACT domain HD PF01966.22 AAZ36567.1 - 2.7e-11 43.7 2.9 1.6e-10 41.2 1.5 2.5 2 0 0 2 2 2 1 HD domain CENP-O PF09496.10 AAZ36567.1 - 0.021 14.8 3.3 0.022 14.7 0.2 2.5 3 0 0 3 3 3 0 Cenp-O kinetochore centromere component Strumpellin PF10266.9 AAZ36567.1 - 0.03 12.1 0.1 0.046 11.4 0.1 1.2 1 0 0 1 1 1 0 Hereditary spastic paraplegia protein strumpellin Sugar_tr PF00083.24 AAZ36568.1 - 5.9e-34 117.7 21.3 6.9e-34 117.5 21.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 AAZ36568.1 - 2.9e-26 92.2 47.4 1.6e-19 70.0 26.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MCPsignal PF00015.21 AAZ36570.1 - 2e-40 138.4 43.7 2.4e-39 134.9 24.4 3.1 2 1 1 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain dCache_1 PF02743.18 AAZ36570.1 - 1.8e-20 73.8 2.3 9.6e-20 71.4 0.0 2.9 2 1 1 3 3 3 1 Cache domain HAMP PF00672.25 AAZ36570.1 - 2.6e-06 27.7 0.1 2.6e-06 27.7 0.1 3.6 5 0 0 5 5 5 1 HAMP domain Laminin_II PF06009.12 AAZ36570.1 - 0.0021 18.1 26.0 0.025 14.6 4.0 3.7 3 1 1 4 4 4 3 Laminin Domain II DUF648 PF04890.13 AAZ36570.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF648) DASH_Duo1 PF08651.10 AAZ36570.1 - 0.24 11.2 2.7 29 4.5 0.1 3.6 3 0 0 3 3 3 0 DASH complex subunit Duo1 DUF948 PF06103.11 AAZ36570.1 - 2 8.7 26.7 9.2 6.6 0.5 5.4 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 AAZ36570.1 - 2.2 8.5 14.8 2.2 8.4 2.4 3.6 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family FlgM PF04316.13 AAZ36571.1 - 4.1e-18 65.5 0.1 7.7e-18 64.6 0.1 1.4 1 0 0 1 1 1 1 Anti-sigma-28 factor, FlgM DUF4923 PF16270.5 AAZ36571.1 - 0.042 13.7 0.3 0.098 12.5 0.2 1.5 1 1 1 2 2 2 0 Lipocalin-like domain (DUF4923) DUF1811 PF08838.10 AAZ36571.1 - 0.077 13.2 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1811) YbaB_DNA_bd PF02575.16 AAZ36572.1 - 1.9e-32 111.3 13.8 2.2e-32 111.1 13.8 1.0 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family DUF1542 PF07564.11 AAZ36572.1 - 0.013 15.6 1.3 0.013 15.6 1.3 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) GatB_Yqey PF02637.18 AAZ36572.1 - 0.031 14.2 2.1 0.038 13.9 2.1 1.0 1 0 0 1 1 1 0 GatB domain DUF3731 PF12531.8 AAZ36572.1 - 0.087 12.6 1.7 0.1 12.4 1.7 1.1 1 0 0 1 1 1 0 DNA-K related protein BRCC36_C PF18110.1 AAZ36572.1 - 0.13 12.4 1.0 1.5 9.1 0.0 2.1 2 0 0 2 2 2 0 BRCC36 C-terminal helical domain IGPD PF00475.18 AAZ36573.1 - 7.3e-63 211.2 0.3 9.7e-63 210.8 0.3 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Aminotran_3 PF00202.21 AAZ36574.1 - 7.3e-79 265.3 0.0 1.7e-78 264.1 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-III PmbA_TldD PF01523.16 AAZ36575.1 - 9.9e-38 130.6 0.0 1.8e-37 129.7 0.0 1.4 2 0 0 2 2 2 1 Putative modulator of DNA gyrase Chorismate_bind PF00425.18 AAZ36577.1 - 3.5e-98 328.3 0.0 4.2e-97 324.7 0.0 2.1 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 AAZ36577.1 - 1.2e-35 122.8 0.0 3e-33 115.0 0.0 2.8 2 1 0 2 2 2 2 Anthranilate synthase component I, N terminal region FecR PF04773.13 AAZ36578.1 - 5.9e-14 52.5 0.2 9.2e-14 51.9 0.2 1.3 1 0 0 1 1 1 1 FecR protein DUF4880 PF16220.5 AAZ36578.1 - 5.9e-11 42.1 11.5 1.7e-10 40.6 11.5 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4880) DUF3325 PF11804.8 AAZ36579.1 - 6.9e-32 109.6 17.2 8.5e-32 109.3 17.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3325) DUF2975 PF11188.8 AAZ36579.1 - 0.027 14.3 3.1 0.046 13.6 3.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2975) Putative_PNPOx PF01243.20 AAZ36580.1 - 4.2e-15 55.7 0.0 5.8e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase UPF0093 PF03653.13 AAZ36581.1 - 2.1e-56 190.2 8.5 2.3e-56 190.1 8.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0093) CopD PF05425.13 AAZ36581.1 - 4.5e-07 30.2 1.3 4.5e-07 30.2 1.3 1.6 2 0 0 2 2 2 1 Copper resistance protein D DUF2269 PF10027.9 AAZ36581.1 - 0.0098 16.0 10.0 0.062 13.3 10.0 1.9 1 1 0 1 1 1 1 Predicted integral membrane protein (DUF2269) PhaC_N PF07167.13 AAZ36582.1 - 6.9e-66 221.2 0.0 2e-65 219.6 0.0 1.8 2 0 0 2 2 2 1 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus Abhydrolase_1 PF00561.20 AAZ36582.1 - 2.8e-13 50.1 0.0 4.4e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold KdgM PF06178.13 AAZ36583.1 - 3.1e-48 164.3 13.1 3.9e-48 164.0 13.1 1.0 1 0 0 1 1 1 1 Oligogalacturonate-specific porin protein (KdgM) OMP_b-brl PF13505.6 AAZ36583.1 - 0.00014 22.1 12.8 0.0066 16.6 4.0 3.5 1 1 1 2 2 2 2 Outer membrane protein beta-barrel domain DUF2490 PF10677.9 AAZ36583.1 - 0.0014 18.7 1.7 0.0092 15.9 1.6 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2490) DUF3396 PF11876.8 AAZ36584.1 - 2.2e-57 193.9 0.0 2.8e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3396) TEP1_N PF05386.11 AAZ36584.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 TEP1 N-terminal domain GDPD PF03009.17 AAZ36585.1 - 9.5e-32 110.7 0.0 4.8e-30 105.1 0.0 2.1 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 AAZ36585.1 - 1.8e-05 25.0 0.0 3.8e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family PI-PLC-X PF00388.19 AAZ36585.1 - 0.21 11.2 0.0 0.34 10.5 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain FtsK_SpoIIIE PF01580.18 AAZ36586.1 - 7.7e-65 218.6 0.1 1.7e-64 217.5 0.1 1.6 1 1 0 1 1 1 1 FtsK/SpoIIIE family FtsK_4TM PF13491.6 AAZ36586.1 - 1.9e-43 148.1 14.9 2.8e-43 147.6 14.9 1.2 1 0 0 1 1 1 1 4TM region of DNA translocase FtsK/SpoIIIE FtsK_alpha PF17854.1 AAZ36586.1 - 4.3e-32 110.2 0.2 8.9e-32 109.2 0.2 1.6 1 0 0 1 1 1 1 FtsK alpha domain FtsK_gamma PF09397.10 AAZ36586.1 - 4.9e-26 90.3 0.4 9.1e-26 89.4 0.4 1.5 1 0 0 1 1 1 1 Ftsk gamma domain AAA_10 PF12846.7 AAZ36586.1 - 3.5e-06 26.2 0.0 0.00096 18.2 0.0 2.6 2 0 0 2 2 2 2 AAA-like domain DUF87 PF01935.17 AAZ36586.1 - 6e-05 23.2 0.4 0.00015 22.0 0.4 1.6 1 0 0 1 1 1 1 Helicase HerA, central domain T2SSE PF00437.20 AAZ36586.1 - 0.014 14.4 1.2 0.028 13.5 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein TrwB_AAD_bind PF10412.9 AAZ36586.1 - 0.092 11.6 0.1 0.39 9.6 0.0 1.8 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain TniB PF05621.11 AAZ36586.1 - 0.11 11.9 0.4 22 4.4 0.0 3.2 3 0 0 3 3 3 0 Bacterial TniB protein DEAD PF00270.29 AAZ36586.1 - 0.18 11.6 0.3 0.63 9.8 0.3 1.8 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_22 PF13401.6 AAZ36586.1 - 0.27 11.5 0.9 5.5 7.3 0.9 2.4 1 1 0 1 1 1 0 AAA domain DegS PF05384.11 AAZ36586.1 - 0.83 9.1 3.1 0.47 9.9 0.9 1.7 2 0 0 2 2 2 0 Sensor protein DegS RsfS PF02410.15 AAZ36587.1 - 5.6e-30 103.7 0.1 6.9e-30 103.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation PFOR_II PF17147.4 AAZ36587.1 - 0.059 13.7 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II DUF615 PF04751.14 AAZ36588.1 - 1.1e-51 174.9 6.2 1.2e-51 174.7 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF615) STIL_N PF15253.6 AAZ36588.1 - 0.04 12.9 0.1 0.053 12.5 0.1 1.1 1 0 0 1 1 1 0 SCL-interrupting locus protein N-terminus Uso1_p115_C PF04871.13 AAZ36588.1 - 0.51 10.7 3.7 0.25 11.7 1.3 1.8 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Bac_transf PF02397.16 AAZ36589.1 - 2.9e-64 216.1 0.0 4.4e-64 215.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial sugar transferase CoA_binding_3 PF13727.6 AAZ36589.1 - 1.3e-32 113.2 0.0 2.3e-32 112.4 0.0 1.4 1 0 0 1 1 1 1 CoA-binding domain GFO_IDH_MocA PF01408.22 AAZ36589.1 - 0.008 17.0 0.0 0.018 15.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold 2-Hacid_dh_C PF02826.19 AAZ36589.1 - 0.012 15.0 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Response_reg PF00072.24 AAZ36590.1 - 1.5e-26 92.8 0.0 2.2e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAZ36590.1 - 1.4e-23 82.7 0.1 4e-23 81.3 0.1 1.8 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal DUF4136 PF13590.6 AAZ36591.1 - 4.3e-18 66.2 0.2 5.4e-18 65.9 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4136) zf-dskA_traR PF01258.17 AAZ36592.1 - 1.6e-09 37.5 3.2 2.4e-09 37.0 3.2 1.3 1 0 0 1 1 1 1 Prokaryotic dksA/traR C4-type zinc finger CMAS PF02353.20 AAZ36592.1 - 0.081 12.2 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase RPN5_C PF18098.1 AAZ36592.1 - 0.21 11.7 1.3 16 5.7 0.1 2.6 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN5 C-terminal domain DUF393 PF04134.12 AAZ36594.1 - 1.2e-23 84.5 0.0 1.5e-23 84.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF393 tRNA_anti-like PF12869.7 AAZ36595.1 - 0.005 16.5 0.1 0.0093 15.6 0.1 1.5 1 1 0 1 1 1 1 tRNA_anti-like tRNA-synt_His PF13393.6 AAZ36596.1 - 1.9e-118 395.3 0.1 2.4e-118 395.0 0.1 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase adh_short PF00106.25 AAZ36597.1 - 1.4e-43 148.7 0.6 1.7e-43 148.3 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAZ36597.1 - 9.1e-33 113.8 2.9 1.1e-32 113.4 2.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 AAZ36597.1 - 1e-09 38.2 3.0 1.2e-09 38.0 0.7 2.1 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 AAZ36597.1 - 1.1e-08 35.2 3.1 1.3e-08 35.0 3.1 1.3 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 AAZ36597.1 - 1e-06 28.8 2.2 1.4e-06 28.4 2.2 1.2 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 AAZ36597.1 - 2.2e-06 27.0 0.5 3.6e-06 26.3 0.5 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 AAZ36597.1 - 5e-06 26.1 0.3 1.2e-05 24.9 0.1 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase ADH_zinc_N PF00107.26 AAZ36597.1 - 0.011 15.8 0.7 0.018 15.0 0.7 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NmrA PF05368.13 AAZ36597.1 - 0.03 13.9 0.3 0.049 13.2 0.3 1.4 1 0 0 1 1 1 0 NmrA-like family Ferritin PF00210.24 AAZ36598.1 - 1.8e-28 99.3 0.0 2.2e-28 99.0 0.0 1.0 1 0 0 1 1 1 1 Ferritin-like domain TFCD_C PF12612.8 AAZ36598.1 - 0.12 12.2 0.0 0.27 11.0 0.0 1.5 2 0 0 2 2 2 0 Tubulin folding cofactor D C terminal Big_1 PF02369.16 AAZ36599.1 - 0.00042 20.2 0.8 0.0019 18.1 0.2 2.3 3 0 0 3 3 3 1 Bacterial Ig-like domain (group 1) CarboxypepD_reg PF13620.6 AAZ36599.1 - 0.0026 18.0 0.0 1.4 9.3 0.0 2.4 2 0 0 2 2 2 2 Carboxypeptidase regulatory-like domain Invasin_D3 PF09134.10 AAZ36599.1 - 0.0074 16.6 0.0 0.057 13.7 0.0 2.3 3 0 0 3 3 3 1 Invasin, domain 3 fn3_3 PF14686.6 AAZ36599.1 - 0.058 13.2 0.0 0.19 11.5 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide lyase family 4, domain II Cupredoxin_1 PF13473.6 AAZ36599.1 - 0.2 11.8 0.1 0.57 10.3 0.1 1.9 1 1 0 1 1 1 0 Cupredoxin-like domain AA_permease PF00324.21 AAZ36600.1 - 7.2e-117 390.9 46.7 8.4e-117 390.7 46.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 AAZ36600.1 - 2.9e-40 138.4 51.0 3.4e-40 138.2 51.0 1.1 1 0 0 1 1 1 1 Amino acid permease Spore_permease PF03845.13 AAZ36600.1 - 1.7e-07 30.4 20.3 1.7e-07 30.4 20.3 2.9 2 2 0 2 2 2 1 Spore germination protein Epiglycanin_C PF14654.6 AAZ36600.1 - 0.48 10.5 6.9 59 3.8 0.3 4.7 5 0 0 5 5 5 0 Mucin, catalytic, TM and cytoplasmic tail region Thiolase_N PF00108.23 AAZ36601.1 - 4.4e-85 285.2 0.4 6.2e-85 284.7 0.4 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 AAZ36601.1 - 5.8e-50 168.1 0.7 5.8e-50 168.1 0.7 2.0 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 AAZ36601.1 - 0.00016 21.4 2.9 0.00039 20.1 1.8 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Glycos_transf_1 PF00534.20 AAZ36602.1 - 1.3e-22 80.1 0.0 2e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAZ36602.1 - 1.1e-15 58.2 0.1 1.9e-15 57.5 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAZ36602.1 - 9e-12 45.3 0.1 1.7e-11 44.4 0.1 1.5 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 AAZ36602.1 - 7.5e-08 32.7 0.0 1.5e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 AAZ36602.1 - 1.9e-06 28.4 0.8 4.6e-06 27.2 0.8 1.7 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain APS_kinase PF01583.20 AAZ36603.1 - 2.1e-65 219.4 0.0 3.1e-65 218.9 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 AAZ36603.1 - 1.8e-05 25.0 0.0 2.5e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AAZ36603.1 - 9.1e-05 23.0 0.0 0.00012 22.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 AAZ36603.1 - 0.0023 18.0 0.0 0.004 17.2 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain KTI12 PF08433.10 AAZ36603.1 - 0.0077 15.7 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_16 PF13191.6 AAZ36603.1 - 0.0099 16.3 0.0 0.014 15.8 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AAZ36603.1 - 0.013 15.2 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MeaB PF03308.16 AAZ36603.1 - 0.025 13.5 0.0 0.042 12.8 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ParA PF10609.9 AAZ36603.1 - 0.032 13.7 0.0 0.042 13.3 0.0 1.2 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 AAZ36603.1 - 0.081 12.6 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ABC_tran PF00005.27 AAZ36603.1 - 0.1 13.1 0.0 0.12 12.9 0.0 1.2 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 AAZ36603.1 - 0.11 11.8 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 AAZ36603.1 - 0.13 12.7 0.0 0.22 11.9 0.0 1.4 1 1 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 AAZ36603.1 - 0.13 12.5 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain PEPCK_ATP PF01293.20 AAZ36603.1 - 0.16 10.6 0.0 0.22 10.2 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase G-alpha PF00503.20 AAZ36603.1 - 0.17 11.0 0.0 0.21 10.7 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit Flg_bb_rod PF00460.20 AAZ36604.1 - 1.6e-08 34.3 0.1 2.8e-08 33.5 0.1 1.5 1 0 0 1 1 1 1 Flagella basal body rod protein Catalase PF00199.19 AAZ36605.1 - 1.7e-179 596.8 0.0 2.4e-179 596.4 0.0 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 AAZ36605.1 - 1e-20 73.7 0.1 1.9e-20 72.8 0.1 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 AAZ36605.1 - 6.3e-19 68.1 0.2 1e-18 67.4 0.2 1.4 1 0 0 1 1 1 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 AAZ36605.1 - 1.8e-10 40.9 0.2 2.8e-10 40.2 0.2 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family Sulfate_transp PF00916.20 AAZ36607.1 - 2e-59 201.2 17.4 2.8e-59 200.8 17.4 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS_2 PF13466.6 AAZ36607.1 - 6.6e-06 26.4 0.0 2.8e-05 24.4 0.0 2.1 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 AAZ36607.1 - 9.9e-06 25.9 6.6 9.9e-06 25.9 6.6 4.3 4 0 0 4 4 4 1 Molybdate transporter of MFS superfamily HCO3_cotransp PF00955.21 AAZ36607.1 - 2.1 7.0 11.8 0.2 10.4 1.6 3.0 2 1 1 3 3 3 0 HCO3- transporter family DsbC PF11412.8 AAZ36608.1 - 1.2e-31 109.2 0.0 1.9e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 Disulphide bond corrector protein DsbC Thioredoxin_7 PF13899.6 AAZ36608.1 - 6.5e-13 48.7 0.0 1.7e-12 47.3 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin-like DsbD PF02683.15 AAZ36608.1 - 6.2e-11 42.6 17.1 6.2e-11 42.6 17.1 1.7 1 1 1 2 2 2 1 Cytochrome C biogenesis protein transmembrane region DsbD_2 PF13386.6 AAZ36608.1 - 6.1e-08 32.8 24.9 6.1e-08 32.8 24.9 2.8 1 1 3 4 4 4 1 Cytochrome C biogenesis protein transmembrane region Thioredoxin_2 PF13098.6 AAZ36608.1 - 8.1e-07 29.5 0.0 1.8e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.20 AAZ36608.1 - 4.1e-05 23.5 0.0 8.1e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Phage_tail_APC PF16778.5 AAZ36609.1 - 0.039 13.8 3.1 0.097 12.6 3.1 1.9 1 1 0 1 1 1 0 Phage tail assembly chaperone protein Glyco_hydro_18 PF00704.28 AAZ36610.1 - 5.8e-26 92.0 2.8 1.1e-25 91.1 0.8 2.4 2 1 0 2 2 2 1 Glycosyl hydrolases family 18 fn3 PF00041.21 AAZ36610.1 - 4.3e-19 68.6 17.8 6.2e-07 29.7 0.2 5.7 5 1 0 5 5 5 4 Fibronectin type III domain fn3_2 PF16893.5 AAZ36610.1 - 2e-10 40.7 3.4 0.0022 18.1 1.1 4.4 4 0 0 4 4 4 4 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 AAZ36610.1 - 1.7e-05 25.3 22.2 0.072 13.7 6.3 5.8 3 3 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain RGI_lyase PF18370.1 AAZ36610.1 - 8.1e-05 22.9 5.8 0.0017 18.6 1.3 3.3 3 0 0 3 3 3 1 Rhamnogalacturonan I lyases beta-sheet domain fn3_4 PF16794.5 AAZ36610.1 - 0.0097 15.8 1.4 18 5.3 0.0 4.1 5 0 0 5 5 5 2 Fibronectin-III type domain DUF2369 PF10179.9 AAZ36610.1 - 0.89 10.0 2.6 14 6.2 0.0 3.4 4 0 0 4 4 4 0 Uncharacterised conserved protein (DUF2369) UbiD PF01977.16 AAZ36611.1 - 2.2e-172 573.5 0.0 2.6e-172 573.3 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase MlaD PF02470.20 AAZ36612.1 - 2.6e-35 120.6 0.8 6.2e-12 45.6 0.0 3.6 3 0 0 3 3 3 3 MlaD protein FlgH PF02107.16 AAZ36613.1 - 2.2e-58 196.6 0.1 2.5e-58 196.4 0.1 1.0 1 0 0 1 1 1 1 Flagellar L-ring protein GatB_N PF02934.15 AAZ36614.1 - 1.1e-113 379.1 0.0 1.5e-113 378.7 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 AAZ36614.1 - 9.8e-52 174.8 2.3 1.7e-51 174.0 2.3 1.4 1 0 0 1 1 1 1 GatB domain PNTB PF02233.16 AAZ36615.1 - 6.8e-187 622.0 22.1 7.8e-187 621.8 22.1 1.0 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit TPP_enzyme_M PF00205.22 AAZ36615.1 - 0.00044 20.0 0.2 0.0061 16.3 0.2 2.7 1 1 1 2 2 2 1 Thiamine pyrophosphate enzyme, central domain HDOD PF08668.12 AAZ36616.1 - 2.5e-52 177.2 0.0 3.1e-52 176.9 0.0 1.1 1 0 0 1 1 1 1 HDOD domain HD PF01966.22 AAZ36616.1 - 1.9e-05 24.9 0.0 8e-05 22.9 0.0 2.0 2 1 0 2 2 2 1 HD domain SLBB PF10531.9 AAZ36616.1 - 0.15 12.0 0.1 0.31 10.9 0.1 1.5 1 0 0 1 1 1 0 SLBB domain ORF6C PF10552.9 AAZ36617.1 - 0.088 12.9 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 ORF6C domain STAS_2 PF13466.6 AAZ36618.1 - 2.7e-06 27.6 0.2 3.9e-06 27.1 0.2 1.3 1 0 0 1 1 1 1 STAS domain STAS PF01740.21 AAZ36618.1 - 3.4e-05 23.5 0.2 5e-05 22.9 0.2 1.2 1 0 0 1 1 1 1 STAS domain DUF4477 PF14780.6 AAZ36618.1 - 0.048 13.3 0.1 7.5 6.1 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4477) AsnC_trans_reg PF01037.21 AAZ36619.1 - 5.9e-21 74.2 0.1 8.9e-21 73.6 0.1 1.3 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_AsnC-type PF13404.6 AAZ36619.1 - 8.1e-17 60.8 0.1 1.4e-16 60.0 0.1 1.4 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 AAZ36619.1 - 3.1e-16 58.7 0.0 4.4e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 AAZ36619.1 - 0.00027 20.8 0.1 0.00041 20.2 0.1 1.3 1 0 0 1 1 1 1 MarR family HTH_11 PF08279.12 AAZ36619.1 - 0.00046 20.1 0.0 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 HTH domain HTH_IclR PF09339.10 AAZ36619.1 - 0.0027 17.5 0.0 0.0047 16.7 0.0 1.3 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_Crp_2 PF13545.6 AAZ36619.1 - 0.026 14.5 0.1 0.1 12.6 0.0 2.0 2 1 0 2 2 2 0 Crp-like helix-turn-helix domain MarR_2 PF12802.7 AAZ36619.1 - 0.034 14.0 0.1 0.058 13.3 0.1 1.3 1 0 0 1 1 1 0 MarR family HTH_20 PF12840.7 AAZ36619.1 - 0.058 13.5 0.0 0.099 12.7 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_1 PF00126.27 AAZ36619.1 - 0.061 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_39 PF14090.6 AAZ36619.1 - 0.087 12.6 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain adh_short_C2 PF13561.6 AAZ36620.1 - 2.8e-48 164.5 1.4 9e-48 162.9 0.4 2.1 2 1 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAZ36620.1 - 3.5e-40 137.6 0.7 2.9e-39 134.6 0.3 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 AAZ36620.1 - 2.3e-17 63.5 2.7 1.4e-16 60.9 0.6 2.3 2 1 0 2 2 2 1 KR domain Epimerase PF01370.21 AAZ36620.1 - 7.6e-07 28.8 0.1 1.2e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 AAZ36620.1 - 0.082 12.2 0.0 0.26 10.6 0.0 1.8 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Sacchrp_dh_NADP PF03435.18 AAZ36620.1 - 0.12 12.6 0.4 1.2 9.4 0.2 2.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain HATPase_c PF02518.26 AAZ36621.1 - 3.7e-17 62.8 0.0 6.3e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase dCache_1 PF02743.18 AAZ36621.1 - 1.5e-14 54.4 0.5 2.8e-14 53.5 0.0 1.6 2 0 0 2 2 2 1 Cache domain HisKA PF00512.25 AAZ36621.1 - 1.2e-09 38.1 1.6 1.2e-09 38.1 1.6 2.5 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 AAZ36621.1 - 0.0002 21.3 0.0 0.00052 20.0 0.0 1.8 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_5 PF14501.6 AAZ36621.1 - 0.0032 17.3 0.0 0.007 16.2 0.0 1.5 1 0 0 1 1 1 1 GHKL domain HATPase_c_3 PF13589.6 AAZ36621.1 - 0.014 15.2 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase sCache_3_2 PF17203.4 AAZ36621.1 - 0.03 14.5 0.3 0.13 12.3 0.0 2.2 2 0 0 2 2 2 0 Single cache domain 3 DUF2721 PF11026.8 AAZ36621.1 - 1.3 8.9 7.4 0.83 9.6 0.5 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF2721) ICL PF00463.21 AAZ36622.1 - 5.1e-109 365.1 0.8 2.8e-58 197.7 0.0 2.0 1 1 1 2 2 2 2 Isocitrate lyase family PEP_mutase PF13714.6 AAZ36622.1 - 2.1e-19 69.9 0.0 4.5e-19 68.9 0.0 1.5 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DUF1440 PF07274.12 AAZ36623.1 - 3.5e-49 166.6 2.6 4e-49 166.4 2.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1440) YqhR PF11085.8 AAZ36623.1 - 1.4 8.8 6.0 0.91 9.4 1.9 2.1 1 1 1 2 2 2 0 Conserved membrane protein YqhR BPD_transp_1 PF00528.22 AAZ36624.1 - 2.1e-19 70.0 13.3 2.1e-19 70.0 13.3 1.8 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component PLDc_2 PF13091.6 AAZ36625.1 - 1.1e-42 145.1 0.0 5.2e-27 94.3 0.0 2.1 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 AAZ36625.1 - 2.6e-07 30.5 1.4 0.00084 19.4 0.1 2.4 2 0 0 2 2 2 2 Phospholipase D Active site motif DUF3565 PF12088.8 AAZ36626.1 - 1.6e-27 95.2 4.7 2.1e-27 94.8 4.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3565) zinc_ribbon_16 PF17034.5 AAZ36626.1 - 0.031 14.5 0.0 0.038 14.2 0.0 1.3 1 0 0 1 1 1 0 Zinc-ribbon like family HTH_11 PF08279.12 AAZ36628.1 - 3e-18 65.5 0.1 7.5e-18 64.2 0.1 1.7 1 0 0 1 1 1 1 HTH domain WYL PF13280.6 AAZ36628.1 - 9.5e-07 29.0 0.2 1.7e-06 28.2 0.2 1.3 1 0 0 1 1 1 1 WYL domain HTH_DeoR PF08220.12 AAZ36628.1 - 1.3e-05 24.8 0.2 3e-05 23.7 0.2 1.6 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_29 PF13551.6 AAZ36628.1 - 0.015 15.3 0.3 0.035 14.1 0.3 1.7 1 0 0 1 1 1 0 Winged helix-turn helix Put_DNA-bind_N PF06971.13 AAZ36628.1 - 0.021 14.8 0.1 0.085 12.9 0.0 1.9 2 0 0 2 2 2 0 Putative DNA-binding protein N-terminus HTH_23 PF13384.6 AAZ36628.1 - 0.037 13.8 0.8 0.37 10.7 0.8 2.5 1 1 0 1 1 1 0 Homeodomain-like domain HTH_IclR PF09339.10 AAZ36628.1 - 0.038 13.8 2.5 0.082 12.7 2.5 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain HrcA_DNA-bdg PF03444.15 AAZ36628.1 - 0.19 11.4 0.0 0.75 9.5 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding EAL PF00563.20 AAZ36630.1 - 4.5e-69 232.6 0.3 3.9e-68 229.5 0.1 2.6 3 0 0 3 3 3 1 EAL domain GGDEF PF00990.21 AAZ36630.1 - 4.9e-44 149.9 0.0 9.1e-44 149.0 0.0 1.5 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Response_reg PF00072.24 AAZ36630.1 - 1.7e-24 86.2 0.0 3.7e-24 85.0 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain PAS PF00989.25 AAZ36630.1 - 5.7e-08 32.8 0.0 1.6e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AAZ36630.1 - 3.3e-05 24.1 0.0 8.7e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 AAZ36630.1 - 3.6e-05 23.7 0.0 0.00021 21.2 0.0 2.3 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 AAZ36630.1 - 0.00035 20.8 0.1 0.0018 18.5 0.0 2.3 2 0 0 2 2 2 1 PAS fold PAS_7 PF12860.7 AAZ36630.1 - 0.11 12.6 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 PAS fold Lipoprotein_9 PF03180.14 AAZ36631.1 - 6.8e-97 323.2 2.2 7.7e-97 323.0 2.2 1.0 1 0 0 1 1 1 1 NLPA lipoprotein Response_reg PF00072.24 AAZ36632.1 - 1.6e-26 92.7 0.1 2.3e-26 92.1 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AAZ36632.1 - 5.2e-21 73.9 0.2 1.1e-20 72.9 0.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4 PF04545.16 AAZ36632.1 - 0.027 14.0 0.0 0.06 12.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 AAZ36632.1 - 0.15 11.8 0.4 1.5 8.6 0.0 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_31 PF13560.6 AAZ36633.1 - 2.1e-07 31.2 0.1 2.5e-07 30.9 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 AAZ36633.1 - 1.2e-06 28.4 0.0 1.4e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 AAZ36633.1 - 7.5e-05 22.7 0.0 9.4e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix KorB PF08535.10 AAZ36633.1 - 0.0068 16.4 0.0 0.0092 16.0 0.0 1.3 1 0 0 1 1 1 1 KorB domain HTH_23 PF13384.6 AAZ36633.1 - 0.0091 15.8 0.0 0.015 15.1 0.0 1.4 1 1 0 1 1 1 1 Homeodomain-like domain Sigma70_r4 PF04545.16 AAZ36633.1 - 0.03 13.9 0.2 0.065 12.8 0.0 1.6 2 0 0 2 2 2 0 Sigma-70, region 4 UBX PF00789.20 AAZ36633.1 - 0.041 14.1 0.0 0.054 13.7 0.0 1.2 1 0 0 1 1 1 0 UBX domain HTH_38 PF13936.6 AAZ36633.1 - 0.064 13.0 0.0 0.099 12.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.6 AAZ36633.1 - 0.087 12.4 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF2396 PF09654.10 AAZ36633.1 - 0.091 12.9 0.0 0.096 12.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2396) HTH_37 PF13744.6 AAZ36633.1 - 0.097 12.6 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain ABC_tran PF00005.27 AAZ36634.1 - 1e-60 204.2 0.1 8.1e-30 104.1 0.0 2.2 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 AAZ36634.1 - 9.6e-18 64.4 0.0 5.2e-09 35.9 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AAZ36634.1 - 3.1e-13 50.2 8.1 0.0004 20.3 0.4 4.0 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system oligo_HPY PF08352.12 AAZ36634.1 - 1.7e-11 44.5 0.0 1e-05 25.9 0.0 2.4 2 0 0 2 2 2 2 Oligopeptide/dipeptide transporter, C-terminal region AAA_22 PF13401.6 AAZ36634.1 - 2e-10 41.1 3.1 7.3e-05 23.1 0.1 3.3 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 AAZ36634.1 - 8.2e-09 35.1 0.6 0.0015 18.2 0.2 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 AAZ36634.1 - 1.6e-07 31.8 4.4 0.0028 18.1 0.5 2.7 2 2 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 AAZ36634.1 - 2.7e-05 24.2 0.2 0.15 12.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 AAZ36634.1 - 4.5e-05 23.0 0.1 0.07 12.6 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region RsgA_GTPase PF03193.16 AAZ36634.1 - 0.0002 21.3 0.5 0.073 13.0 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase DUF87 PF01935.17 AAZ36634.1 - 0.00022 21.4 2.5 0.17 11.9 0.1 2.4 2 0 0 2 2 2 2 Helicase HerA, central domain NACHT PF05729.12 AAZ36634.1 - 0.00067 19.6 3.6 0.64 9.9 0.1 3.0 3 0 0 3 3 3 2 NACHT domain NB-ARC PF00931.22 AAZ36634.1 - 0.00095 18.4 1.5 0.47 9.6 0.2 2.6 3 0 0 3 3 3 2 NB-ARC domain AAA_33 PF13671.6 AAZ36634.1 - 0.00096 19.3 0.1 0.79 9.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 AAZ36634.1 - 0.0012 19.3 0.0 2 8.9 0.0 3.3 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 AAZ36634.1 - 0.0014 18.3 0.3 1.1 9.0 0.0 3.0 3 0 0 3 3 3 1 IstB-like ATP binding protein TniB PF05621.11 AAZ36634.1 - 0.0024 17.3 1.9 6.7 6.1 0.2 3.9 4 0 0 4 4 4 0 Bacterial TniB protein AIG1 PF04548.16 AAZ36634.1 - 0.0026 17.1 0.5 0.34 10.2 0.1 2.3 2 0 0 2 2 2 1 AIG1 family ATP-synt_ab PF00006.25 AAZ36634.1 - 0.0027 17.4 0.0 0.17 11.5 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.22 AAZ36634.1 - 0.0033 17.8 0.0 4.2 7.8 0.0 2.4 2 0 0 2 2 2 0 RNA helicase DUF2075 PF09848.9 AAZ36634.1 - 0.0033 16.7 0.0 1.9 7.7 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.21 AAZ36634.1 - 0.0038 16.6 0.2 0.3 10.4 0.0 2.8 3 0 0 3 3 2 1 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.23 AAZ36634.1 - 0.0053 16.8 0.1 0.24 11.5 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase NTPase_1 PF03266.15 AAZ36634.1 - 0.006 16.5 2.0 2.3 8.1 0.1 3.0 4 0 0 4 4 2 1 NTPase PRK PF00485.18 AAZ36634.1 - 0.0067 16.2 0.0 3.4 7.4 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family APS_kinase PF01583.20 AAZ36634.1 - 0.0095 15.8 0.2 6.2 6.7 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_23 PF13476.6 AAZ36634.1 - 0.01 16.3 0.1 0.17 12.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 AAZ36634.1 - 0.012 14.4 0.3 6.7 5.4 0.0 3.4 3 1 0 3 3 3 0 Predicted ATPase of the ABC class FtsK_SpoIIIE PF01580.18 AAZ36634.1 - 0.013 14.8 0.1 3.8 6.8 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_25 PF13481.6 AAZ36634.1 - 0.015 14.8 0.4 8.5 5.9 0.0 3.5 4 0 0 4 4 3 0 AAA domain AAA_24 PF13479.6 AAZ36634.1 - 0.022 14.5 0.3 4.8 6.8 0.1 2.2 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 AAZ36634.1 - 0.03 14.6 0.4 2.6 8.3 0.0 3.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit T2SSE PF00437.20 AAZ36634.1 - 0.031 13.3 0.1 7.5 5.5 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein ATPase PF06745.13 AAZ36634.1 - 0.032 13.6 0.4 3.3 7.0 0.1 2.4 2 0 0 2 2 2 0 KaiC Sigma54_activat PF00158.26 AAZ36634.1 - 0.034 13.9 5.0 3.2 7.4 0.0 3.1 4 0 0 4 4 3 0 Sigma-54 interaction domain AAA_30 PF13604.6 AAZ36634.1 - 0.036 13.8 0.4 2.2 8.0 0.1 2.9 2 1 0 2 2 2 0 AAA domain TsaE PF02367.17 AAZ36634.1 - 0.057 13.4 0.6 15 5.6 0.1 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MobB PF03205.14 AAZ36634.1 - 0.073 13.0 0.2 2.4 8.0 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B HopA1 PF17914.1 AAZ36634.1 - 0.098 12.4 0.0 2.3 7.9 0.0 2.4 2 0 0 2 2 2 0 HopA1 effector protein family PPV_E1_C PF00519.17 AAZ36634.1 - 0.12 11.2 0.0 0.82 8.4 0.0 1.9 2 0 0 2 2 2 0 Papillomavirus helicase AAA_18 PF13238.6 AAZ36634.1 - 0.14 12.7 0.5 2.6 8.6 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_15 PF13175.6 AAZ36634.1 - 0.16 11.7 0.0 8.7 5.9 0.0 2.6 2 1 1 3 3 3 0 AAA ATPase domain Hpr_kinase_C PF07475.12 AAZ36634.1 - 0.21 11.1 3.7 0.31 10.6 0.2 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Zeta_toxin PF06414.12 AAZ36634.1 - 0.21 10.8 0.5 20 4.4 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin Roc PF08477.13 AAZ36634.1 - 0.22 11.7 0.1 19 5.5 0.1 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 AAZ36634.1 - 0.23 10.6 0.2 18 4.3 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit Pox_A32 PF04665.12 AAZ36634.1 - 0.7 9.3 2.8 5.7 6.3 0.0 2.4 3 0 0 3 3 2 0 Poxvirus A32 protein SBP_bac_5 PF00496.22 AAZ36635.1 - 2e-94 316.6 3.6 2e-94 316.6 3.6 1.5 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 5 Middle SBP_bac_3 PF00497.20 AAZ36635.1 - 0.12 11.8 0.8 2.6 7.4 0.0 2.6 2 1 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 SufE PF02657.15 AAZ36636.1 - 1.7e-40 137.7 0.0 1.9e-40 137.5 0.0 1.0 1 0 0 1 1 1 1 Fe-S metabolism associated domain HBM PF16591.5 AAZ36637.1 - 7e-68 228.8 16.2 7e-68 228.8 16.2 3.5 3 1 0 3 3 3 1 Helical bimodular sensor domain MCPsignal PF00015.21 AAZ36637.1 - 5.3e-45 153.3 23.9 5.3e-45 153.3 23.9 4.4 3 1 1 4 4 4 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AAZ36637.1 - 1.8e-10 41.0 13.5 1.6e-09 38.0 2.0 6.0 5 1 0 5 5 5 1 HAMP domain 4HB_MCP_1 PF12729.7 AAZ36637.1 - 1.1e-05 25.1 3.3 1.1e-05 25.1 3.3 5.2 4 2 0 4 4 4 1 Four helix bundle sensory module for signal transduction DUF948 PF06103.11 AAZ36637.1 - 0.0033 17.6 1.3 0.0033 17.6 1.3 6.5 5 2 3 8 8 8 1 Bacterial protein of unknown function (DUF948) KxDL PF10241.9 AAZ36637.1 - 0.078 13.3 13.4 0.45 10.8 0.3 4.6 5 1 0 5 5 5 0 Uncharacterized conserved protein Syntaxin_2 PF14523.6 AAZ36637.1 - 0.1 13.0 18.9 1 9.7 0.4 5.7 5 1 0 6 6 6 0 Syntaxin-like protein DED PF01335.21 AAZ36637.1 - 0.12 12.7 0.2 0.33 11.3 0.2 1.8 1 0 0 1 1 1 0 Death effector domain Fib_alpha PF08702.10 AAZ36637.1 - 1.5 9.0 15.1 5.2 7.3 2.6 4.5 4 2 0 4 4 4 0 Fibrinogen alpha/beta chain family ZapB PF06005.12 AAZ36637.1 - 6 7.4 8.5 15 6.1 0.5 4.0 3 1 0 3 3 3 0 Cell division protein ZapB DUF724 PF05266.14 AAZ36637.1 - 7.1 6.4 12.0 7.7 6.3 0.6 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF724) TMPIT PF07851.13 AAZ36637.1 - 8.1 5.6 9.1 7.9 5.6 1.1 3.3 3 0 0 3 3 3 0 TMPIT-like protein BPD_transp_1 PF00528.22 AAZ36638.1 - 2.5e-13 50.2 14.0 2.5e-13 50.2 14.0 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component Bac_export_2 PF01312.19 AAZ36638.1 - 9 5.4 6.8 9.9 5.3 5.3 1.7 1 1 1 2 2 2 0 FlhB HrpN YscU SpaS Family SBP_bac_5 PF00496.22 AAZ36639.1 - 2.3e-95 319.8 9.4 2.8e-95 319.5 9.4 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle VirJ PF06057.11 AAZ36640.1 - 1.5e-74 250.1 0.1 2.1e-74 249.6 0.1 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Cutinase PF01083.22 AAZ36640.1 - 0.009 16.0 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.20 AAZ36640.1 - 0.02 14.5 0.1 0.038 13.6 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AAZ36640.1 - 0.035 13.4 0.0 0.14 11.4 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF1970 PF09301.10 AAZ36640.1 - 0.084 13.1 0.1 0.29 11.4 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1970) OSTMP1 PF09777.9 AAZ36640.1 - 0.25 10.7 0.1 0.37 10.1 0.1 1.2 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor Tagatose_6_P_K PF08013.11 AAZ36640.1 - 0.28 9.8 0.8 1.9 7.1 0.1 1.9 1 1 1 2 2 2 0 Tagatose 6 phosphate kinase Apq12 PF12716.7 AAZ36640.1 - 5.4 7.0 9.2 9 6.3 9.2 1.4 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis Transposase_mut PF00872.18 AAZ36641.1 - 1.5e-117 392.7 0.0 1.9e-117 392.3 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ36641.1 - 7.7e-05 23.0 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain DUF4844 PF16133.5 AAZ36641.1 - 0.23 12.0 0.0 0.55 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) Oxidored_FMN PF00724.20 AAZ36642.1 - 3.1e-72 243.7 0.0 7.5e-71 239.2 0.0 2.0 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Lip_A_acyltrans PF03279.13 AAZ36643.1 - 2.8e-13 49.7 0.0 3.6e-13 49.3 0.0 1.3 1 1 0 1 1 1 1 Bacterial lipid A biosynthesis acyltransferase DUF1874 PF08960.10 AAZ36643.1 - 0.017 15.3 0.0 0.028 14.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1874) Peptidase_S11 PF00768.20 AAZ36644.1 - 5.4e-73 245.4 1.0 7.1e-73 245.0 1.0 1.1 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Beta-lactamase2 PF13354.6 AAZ36644.1 - 1.8e-07 30.9 0.3 2.5e-07 30.5 0.3 1.3 1 0 0 1 1 1 1 Beta-lactamase enzyme family Beta-lactamase PF00144.24 AAZ36644.1 - 0.00056 19.3 0.7 0.032 13.5 0.1 2.2 2 0 0 2 2 2 2 Beta-lactamase Peptidase_S13 PF02113.15 AAZ36644.1 - 0.0008 18.2 0.5 0.024 13.4 0.1 2.1 2 0 0 2 2 2 2 D-Ala-D-Ala carboxypeptidase 3 (S13) family Flg_bbr_C PF06429.13 AAZ36644.1 - 0.065 13.4 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Flagellar basal body rod FlgEFG protein C-terminal GreA_GreB PF01272.19 AAZ36645.1 - 3e-16 59.1 0.0 4.3e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Transcription elongation factor, GreA/GreB, C-term Rnk_N PF14760.6 AAZ36645.1 - 2.1e-12 47.3 0.3 3e-12 46.8 0.3 1.3 1 0 0 1 1 1 1 Rnk N-terminus FAA_hydrolase PF01557.18 AAZ36648.1 - 2.9e-66 223.3 0.0 3.7e-66 222.9 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family TonB_C PF03544.14 AAZ36649.1 - 3e-22 78.9 0.0 7.4e-22 77.6 0.0 1.7 1 0 0 1 1 1 1 Gram-negative bacterial TonB protein C-terminal TonB_2 PF13103.6 AAZ36649.1 - 0.0013 18.9 2.0 0.0045 17.2 0.0 2.5 2 0 0 2 2 2 1 TonB C terminal ABC_membrane PF00664.23 AAZ36650.1 - 1.7e-49 169.0 9.9 1.7e-49 169.0 9.9 1.4 2 0 0 2 2 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 AAZ36650.1 - 1.5e-33 116.2 0.0 2.9e-33 115.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AAZ36650.1 - 9.8e-09 35.0 0.7 1.7e-06 27.6 0.1 2.3 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AAZ36650.1 - 0.00045 20.6 0.2 0.0011 19.4 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AAZ36650.1 - 0.00084 19.3 0.0 0.0021 18.0 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 AAZ36650.1 - 0.001 19.4 0.3 0.0096 16.2 0.3 2.3 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 AAZ36650.1 - 0.0046 15.8 0.1 0.022 13.6 0.0 2.1 2 1 0 2 2 2 1 Predicted ATPase of the ABC class AAA_29 PF13555.6 AAZ36650.1 - 0.0055 16.4 0.0 0.019 14.7 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 AAZ36650.1 - 0.017 15.2 0.1 0.038 14.1 0.1 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase DEAD PF00270.29 AAZ36650.1 - 0.022 14.5 0.3 0.1 12.3 0.0 2.2 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_24 PF13479.6 AAZ36650.1 - 0.038 13.7 0.0 0.069 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.8 AAZ36650.1 - 0.04 11.4 0.0 0.058 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF815 PF05673.13 AAZ36650.1 - 0.047 12.8 0.0 0.083 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NB-ARC PF00931.22 AAZ36650.1 - 0.049 12.8 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain G-alpha PF00503.20 AAZ36650.1 - 0.094 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit APS_kinase PF01583.20 AAZ36650.1 - 0.097 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF87 PF01935.17 AAZ36650.1 - 0.11 12.5 0.1 1.4 9.0 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_18 PF13238.6 AAZ36650.1 - 0.12 12.9 0.0 0.27 11.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 AAZ36650.1 - 0.13 12.7 0.3 3.5 8.1 0.1 2.6 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 AAZ36650.1 - 0.13 11.5 0.0 0.63 9.3 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_23 PF13476.6 AAZ36650.1 - 0.22 12.0 0.0 0.64 10.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AAZ36651.1 - 3e-32 112.0 0.0 3.8e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAZ36651.1 - 1e-10 41.9 0.5 1.6e-07 31.5 0.1 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AAZ36651.1 - 1.5e-05 25.4 0.1 2e-05 25.0 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AAZ36651.1 - 0.00018 21.2 0.0 0.0004 20.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AAZ36651.1 - 0.00041 20.3 0.0 0.00074 19.5 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 AAZ36651.1 - 0.00062 20.0 0.1 0.00097 19.4 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AAZ36651.1 - 0.0066 16.6 0.1 0.029 14.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain PIF1 PF05970.14 AAZ36651.1 - 0.018 14.2 0.0 0.026 13.7 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase cobW PF02492.19 AAZ36651.1 - 0.07 12.7 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 AAZ36651.1 - 0.077 13.6 0.0 0.17 12.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 AAZ36651.1 - 0.084 12.4 0.1 0.23 11.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 AAZ36651.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_27 PF13514.6 AAZ36651.1 - 0.13 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AAZ36651.1 - 0.16 12.5 0.0 0.23 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 AAZ36651.1 - 0.18 11.7 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Herpes_Helicase PF02689.14 AAZ36651.1 - 0.34 8.8 0.0 0.4 8.5 0.0 1.0 1 0 0 1 1 1 0 Helicase Peptidase_M16_C PF05193.21 AAZ36652.1 - 4.6e-19 69.1 0.0 9.4e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 AAZ36652.1 - 1.8e-13 50.7 0.0 4.1e-13 49.6 0.0 1.6 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_S24 PF00717.23 AAZ36653.1 - 5.8e-11 42.2 0.0 9.2e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like HTH_3 PF01381.22 AAZ36653.1 - 3e-05 24.0 0.0 7.4e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix TetR_N PF00440.23 AAZ36653.1 - 0.011 15.5 0.0 0.033 14.0 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family HTH_Crp_2 PF13545.6 AAZ36653.1 - 0.1 12.6 0.0 0.38 10.8 0.0 1.9 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain FdhE PF04216.12 AAZ36653.1 - 0.3 10.9 1.6 0.43 10.4 1.6 1.1 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation SBP_bac_5 PF00496.22 AAZ36654.1 - 1.7e-85 287.3 4.8 2e-85 287.0 4.8 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle Cu-oxidase_4 PF02578.15 AAZ36656.1 - 1.3e-74 250.7 0.0 1.4e-74 250.5 0.0 1.0 1 0 0 1 1 1 1 Multi-copper polyphenol oxidoreductase laccase EamA PF00892.20 AAZ36657.1 - 1.1e-35 122.8 36.5 3.9e-18 66.0 15.1 2.0 2 0 0 2 2 2 2 EamA-like transporter family DUF3087 PF11286.8 AAZ36657.1 - 4.3 6.8 4.6 3 7.3 0.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3087) RseC_MucC PF04246.12 AAZ36657.1 - 4.4 7.3 23.1 0.13 12.2 1.8 3.9 2 2 1 4 4 4 0 Positive regulator of sigma(E), RseC/MucC BPD_transp_2 PF02653.16 AAZ36658.1 - 4.9e-35 121.0 26.3 4.9e-35 121.0 26.3 1.9 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component Phospholamban PF04272.14 AAZ36658.1 - 1.5 8.4 6.6 0.32 10.5 0.4 2.5 2 0 0 2 2 2 0 Phospholamban IspA PF04279.15 AAZ36659.1 - 1.1e-61 208.0 13.9 1.3e-61 207.8 13.9 1.0 1 0 0 1 1 1 1 Intracellular septation protein A DUF3021 PF11457.8 AAZ36659.1 - 1.2 9.5 18.6 0.64 10.4 4.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3021) ABC2_membrane_5 PF13346.6 AAZ36659.1 - 4.2 6.9 13.5 3.2 7.2 8.4 2.2 1 1 1 2 2 2 0 ABC-2 family transporter protein HTH_AsnC-type PF13404.6 AAZ36660.1 - 1.4e-14 53.6 0.2 2.3e-14 53.0 0.2 1.4 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 AAZ36660.1 - 3.8e-13 48.8 0.0 5.9e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding AsnC_trans_reg PF01037.21 AAZ36660.1 - 1.6e-12 47.2 0.0 5.7e-12 45.4 0.0 1.9 2 0 0 2 2 2 1 Lrp/AsnC ligand binding domain MarR_2 PF12802.7 AAZ36660.1 - 0.00016 21.5 0.1 0.00031 20.5 0.1 1.4 1 0 0 1 1 1 1 MarR family MarR PF01047.22 AAZ36660.1 - 0.00036 20.4 0.0 0.00062 19.7 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 AAZ36660.1 - 0.01 15.9 0.1 0.017 15.2 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_5 PF01022.20 AAZ36660.1 - 0.017 15.0 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family BRICHOS PF04089.14 AAZ36660.1 - 0.019 15.2 0.0 1 9.6 0.0 2.1 2 0 0 2 2 2 0 BRICHOS domain DUF501 PF04417.12 AAZ36660.1 - 0.03 14.1 0.0 0.054 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF501) TrmB PF01978.19 AAZ36660.1 - 0.035 14.0 0.1 0.068 13.1 0.1 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_1 PF00126.27 AAZ36660.1 - 0.054 13.5 0.2 0.099 12.6 0.2 1.4 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_34 PF13601.6 AAZ36660.1 - 0.066 13.4 0.1 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_28 PF13518.6 AAZ36660.1 - 0.12 12.6 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Fe_dep_repress PF01325.19 AAZ36660.1 - 0.15 12.3 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain DprA_WH PF17782.1 AAZ36660.1 - 0.15 12.2 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 DprA winged helix domain GCV_T PF01571.21 AAZ36661.1 - 2.2e-81 273.0 0.1 2.8e-81 272.7 0.1 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 AAZ36661.1 - 3.1e-15 55.8 0.2 6.6e-15 54.8 0.2 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain POPLD PF08170.12 AAZ36661.1 - 0.023 15.0 0.0 0.04 14.3 0.0 1.4 1 0 0 1 1 1 0 POPLD (NUC188) domain HPPK PF01288.20 AAZ36662.1 - 3.9e-35 120.7 0.0 4.6e-35 120.5 0.0 1.1 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) HATPase_c PF02518.26 AAZ36663.1 - 2e-21 76.6 0.0 4.8e-21 75.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAZ36663.1 - 5.5e-12 45.5 0.1 1.6e-11 44.0 0.0 1.9 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 AAZ36663.1 - 1.5e-05 24.9 0.0 5e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_5 PF14501.6 AAZ36663.1 - 0.00059 19.7 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 GHKL domain DUF445 PF04286.12 AAZ36663.1 - 0.021 14.7 1.7 0.031 14.1 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) RsbRD_N PF14361.6 AAZ36663.1 - 0.083 13.6 4.8 0.13 13.0 1.3 2.3 1 1 1 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain CAF1-p150_C2 PF15539.6 AAZ36663.1 - 1.2 8.5 3.5 1.2 8.5 0.5 2.0 1 1 1 2 2 2 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term FAD_binding_6 PF00970.24 AAZ36664.1 - 2.6e-09 37.3 0.0 4.2e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 AAZ36664.1 - 1.2e-08 35.6 0.0 2.3e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.22 AAZ36664.1 - 2.5e-08 34.4 0.0 4.7e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Globin oligo_HPY PF08352.12 AAZ36665.1 - 5.3e-13 49.3 3.1 6.2e-13 49.1 1.4 1.9 2 0 0 2 2 2 1 Oligopeptide/dipeptide transporter, C-terminal region APH PF01636.23 AAZ36666.1 - 5.5e-34 118.2 3.4 5.7e-34 118.1 2.4 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 AAZ36666.1 - 0.00087 18.7 0.0 0.0038 16.6 0.0 1.8 2 0 0 2 2 2 1 Ecdysteroid kinase DUF1679 PF07914.11 AAZ36666.1 - 0.025 13.4 0.0 0.038 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) STAS_2 PF13466.6 AAZ36668.1 - 2.2e-10 40.7 0.0 2.7e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 STAS domain STAS PF01740.21 AAZ36668.1 - 1e-06 28.4 0.0 1.4e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 STAS domain PAS_3 PF08447.12 AAZ36669.1 - 1e-62 208.4 4.3 1.5e-16 60.5 0.0 4.4 4 0 0 4 4 4 4 PAS fold PAS_9 PF13426.7 AAZ36669.1 - 1.5e-48 163.3 0.1 4.3e-12 46.2 0.0 4.3 4 0 0 4 4 4 4 PAS domain PAS_4 PF08448.10 AAZ36669.1 - 2.7e-45 153.1 0.1 4.6e-11 42.9 0.0 5.1 5 0 0 5 5 5 4 PAS fold MCPsignal PF00015.21 AAZ36669.1 - 5.5e-42 143.5 14.7 5.5e-42 143.5 14.7 2.1 1 1 1 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain PAS PF00989.25 AAZ36669.1 - 1.8e-31 108.5 0.0 2.9e-07 30.5 0.0 4.7 4 0 0 4 4 4 4 PAS fold PAS_8 PF13188.7 AAZ36669.1 - 1.8e-10 40.6 0.3 0.14 12.2 0.0 4.7 5 0 0 5 5 5 3 PAS domain sCache_3_3 PF17202.4 AAZ36669.1 - 0.0032 17.9 0.6 22 5.5 0.1 4.4 4 0 0 4 4 4 0 Single cache domain 3 Fapy_DNA_glyco PF01149.24 AAZ36669.1 - 0.0037 17.9 0.1 6.3 7.4 0.0 4.0 1 1 0 3 3 3 1 Formamidopyrimidine-DNA glycosylase N-terminal domain PAS_7 PF12860.7 AAZ36669.1 - 1.4 9.1 7.4 69 3.6 0.0 5.5 5 2 0 5 5 5 0 PAS fold HlyD PF00529.20 AAZ36670.1 - 9e-18 63.9 0.1 1.3e-17 63.4 0.1 1.3 1 0 0 1 1 1 1 HlyD membrane-fusion protein of T1SS HlyD_3 PF13437.6 AAZ36670.1 - 2.5e-16 60.3 1.0 1.4e-12 48.3 0.1 2.4 2 0 0 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 AAZ36670.1 - 1.4e-08 34.2 5.2 0.00098 18.4 0.7 2.3 2 0 0 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 AAZ36670.1 - 7.7e-08 32.0 13.1 1.5e-07 31.1 0.5 4.1 5 0 0 5 5 5 2 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AAZ36670.1 - 1.2e-05 25.1 0.3 0.00044 20.0 0.0 2.5 2 0 0 2 2 2 1 Biotin-requiring enzyme Filament PF00038.21 AAZ36670.1 - 0.015 14.9 1.1 0.67 9.5 1.5 2.3 2 1 0 2 2 2 0 Intermediate filament protein PTS_EIIA_1 PF00358.20 AAZ36670.1 - 0.016 15.0 0.2 0.15 11.8 0.0 2.2 2 1 0 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 FliJ PF02050.16 AAZ36670.1 - 0.55 10.5 13.4 0.037 14.3 7.3 2.2 2 1 0 2 2 2 0 Flagellar FliJ protein LMWPc PF01451.21 AAZ36671.1 - 6.2e-36 123.9 0.0 7e-36 123.7 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Pro_racemase PF05544.11 AAZ36671.1 - 0.0065 15.6 0.0 0.022 13.8 0.0 1.7 2 0 0 2 2 2 1 Proline racemase HEAT_2 PF13646.6 AAZ36671.1 - 0.033 14.6 0.4 0.051 14.0 0.4 1.3 1 0 0 1 1 1 0 HEAT repeats Pertussis_S1 PF02917.14 AAZ36671.1 - 0.11 12.3 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Pertussis toxin, subunit 1 HlyD_D23 PF16576.5 AAZ36672.1 - 4.1e-19 68.7 6.5 1.1e-18 67.3 5.3 2.2 2 1 0 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AAZ36672.1 - 8.8e-15 55.3 1.7 1e-09 39.0 0.0 3.1 2 1 1 3 3 3 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AAZ36672.1 - 4.5e-10 39.2 0.9 1.6e-06 27.8 0.8 3.2 2 0 0 2 2 2 2 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AAZ36672.1 - 1.5e-06 27.9 0.1 0.00096 18.9 0.3 2.4 2 0 0 2 2 2 2 Biotin-requiring enzyme PTS_EIIA_1 PF00358.20 AAZ36672.1 - 0.00042 20.1 0.0 0.035 13.9 0.0 2.4 2 0 0 2 2 2 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 RnfC_N PF13375.6 AAZ36672.1 - 0.0036 17.2 0.0 2.4 8.2 0.0 2.4 2 0 0 2 2 2 2 RnfC Barrel sandwich hybrid domain HlyD_2 PF12700.7 AAZ36672.1 - 0.0056 15.5 0.0 0.007 15.2 0.0 1.1 1 0 0 1 1 1 1 HlyD family secretion protein OEP PF02321.18 AAZ36672.1 - 0.01 15.7 12.2 0.021 14.7 12.2 1.5 1 0 0 1 1 1 1 Outer membrane efflux protein Peptidase_M23 PF01551.22 AAZ36672.1 - 0.011 15.9 0.1 1.6 9.0 0.0 2.6 2 1 0 2 2 2 0 Peptidase family M23 Spc7 PF08317.11 AAZ36672.1 - 0.13 11.1 3.5 0.21 10.4 3.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein ABC_tran PF00005.27 AAZ36673.1 - 1.9e-30 106.2 0.0 2.8e-30 105.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAZ36673.1 - 1.8e-07 31.3 0.1 0.008 16.0 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 AAZ36673.1 - 2.2e-06 28.1 0.5 4e-05 24.0 0.5 2.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 AAZ36673.1 - 3.8e-05 23.3 0.0 8.8e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AAZ36673.1 - 0.00012 22.5 0.0 0.00018 21.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 AAZ36673.1 - 0.00029 20.4 0.0 0.36 10.2 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AAZ36673.1 - 0.00039 20.7 0.1 0.0023 18.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 AAZ36673.1 - 0.00049 20.4 0.0 0.032 14.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 AAZ36673.1 - 0.0023 17.8 0.0 0.0039 17.1 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_5 PF07728.14 AAZ36673.1 - 0.0072 16.3 0.3 0.039 14.0 0.1 2.3 2 1 1 3 3 3 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 AAZ36673.1 - 0.012 14.8 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_ATPase PF09818.9 AAZ36673.1 - 0.015 14.1 0.0 0.37 9.5 0.0 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Rad17 PF03215.15 AAZ36673.1 - 0.016 15.1 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain NACHT PF05729.12 AAZ36673.1 - 0.02 14.8 0.1 0.16 11.9 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.6 AAZ36673.1 - 0.037 14.5 0.0 0.062 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 AAZ36673.1 - 0.044 13.5 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 AAZ36673.1 - 0.08 12.7 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.9 AAZ36673.1 - 0.11 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_33 PF13671.6 AAZ36673.1 - 0.12 12.5 0.1 0.24 11.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 AAZ36673.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 AAZ36673.1 - 0.16 12.3 0.0 0.36 11.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Viral_helicase1 PF01443.18 AAZ36673.1 - 0.18 11.5 0.0 0.41 10.4 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase G-alpha PF00503.20 AAZ36673.1 - 0.23 10.6 0.0 0.34 10.0 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Acetyltransf_10 PF13673.7 AAZ36674.1 - 1.7e-16 60.3 0.0 1.9e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAZ36674.1 - 1.5e-09 38.1 0.0 1.9e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAZ36674.1 - 8.5e-08 32.5 0.0 1.5e-07 31.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AAZ36674.1 - 1.9e-07 31.2 0.1 8.8e-07 29.1 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AAZ36674.1 - 0.00048 20.2 0.1 0.0013 18.8 0.0 1.7 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 AAZ36674.1 - 0.17 11.9 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase NBD_C PF17042.5 AAZ36675.1 - 2.7e-13 50.8 1.0 3.1e-13 50.6 1.0 1.1 1 0 0 1 1 1 1 Nucleotide-binding C-terminal domain PK PF00224.21 AAZ36676.1 - 6.9e-123 410.0 0.4 8.9e-123 409.6 0.4 1.0 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 AAZ36676.1 - 4.7e-26 91.3 0.0 2.7e-25 88.9 0.0 2.2 2 1 0 2 2 2 1 Pyruvate kinase, alpha/beta domain Hexapep PF00132.24 AAZ36677.1 - 4.3e-10 38.9 7.0 5.1e-06 26.0 0.8 2.4 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AAZ36677.1 - 0.0011 18.6 4.5 0.0047 16.6 0.8 2.6 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase SATase_N PF06426.14 AAZ36677.1 - 0.036 14.4 0.1 0.064 13.6 0.1 1.4 1 0 0 1 1 1 0 Serine acetyltransferase, N-terminal GlnE PF03710.15 AAZ36678.1 - 1.2e-180 598.2 0.2 3.1e-89 298.7 0.2 2.3 2 0 0 2 2 2 2 Glutamate-ammonia ligase adenylyltransferase GlnD_UR_UTase PF08335.11 AAZ36678.1 - 1.1e-57 194.3 8.8 1.8e-44 151.4 1.8 3.1 3 0 0 3 3 3 2 GlnD PII-uridylyltransferase Gmad2 PF10648.9 AAZ36678.1 - 0.013 15.7 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin-like domain of bacterial spore germination DAO PF01266.24 AAZ36679.1 - 4.6e-06 26.5 0.0 8.4e-05 22.3 0.0 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 AAZ36679.1 - 4.9e-06 25.5 0.0 0.0023 16.7 0.0 2.4 2 0 0 2 2 2 2 HI0933-like protein GIDA PF01134.22 AAZ36679.1 - 0.00015 20.9 0.1 0.059 12.4 0.0 3.0 3 0 0 3 3 3 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 AAZ36679.1 - 0.00019 20.8 0.0 0.0022 17.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 AAZ36679.1 - 0.00025 20.4 0.0 0.0017 17.6 0.0 2.2 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 AAZ36679.1 - 0.0022 17.4 0.5 0.013 14.8 0.0 2.3 2 1 0 3 3 3 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 AAZ36679.1 - 0.0026 16.9 0.4 0.43 9.6 0.8 2.7 2 1 0 2 2 2 2 FAD binding domain FAD_binding_3 PF01494.19 AAZ36679.1 - 0.005 16.1 0.0 0.026 13.8 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 AAZ36679.1 - 0.027 14.4 2.0 0.045 13.7 0.0 2.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding DAO PF01266.24 AAZ36681.1 - 8.4e-67 226.2 0.6 9.6e-67 226.0 0.6 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AAZ36681.1 - 1.3e-10 41.0 0.4 2.6e-10 40.0 0.4 1.5 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 AAZ36681.1 - 3.1e-06 26.2 1.0 0.0074 15.0 0.7 2.3 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.14 AAZ36681.1 - 0.00019 20.7 0.6 0.04 13.1 0.4 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AAZ36681.1 - 0.00036 20.7 0.6 0.00084 19.5 0.6 1.7 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 AAZ36681.1 - 0.0013 18.7 0.2 0.012 15.6 0.1 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 AAZ36681.1 - 0.0033 16.7 0.0 0.44 9.8 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AAZ36681.1 - 0.0042 16.5 0.0 0.015 14.7 0.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 AAZ36681.1 - 0.0044 16.1 0.3 0.52 9.3 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 AAZ36681.1 - 0.0065 15.7 2.4 0.084 12.1 1.1 2.2 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 AAZ36681.1 - 0.0086 15.4 0.4 0.061 12.6 0.8 1.9 2 0 0 2 2 2 1 FAD binding domain GMC_oxred_N PF00732.19 AAZ36681.1 - 0.092 12.1 0.1 2.7 7.3 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase ApbA PF02558.16 AAZ36681.1 - 0.13 11.9 0.7 0.24 11.0 0.7 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 AAZ36681.1 - 0.14 11.7 0.4 0.25 10.9 0.4 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 AAZ36681.1 - 0.55 10.8 5.1 0.37 11.4 0.6 2.8 4 0 0 4 4 3 0 Pyridine nucleotide-disulphide oxidoreductase BPD_transp_1 PF00528.22 AAZ36682.1 - 3.5e-26 92.1 16.1 3.5e-26 92.1 16.1 1.6 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 AAZ36682.1 - 8.8e-05 22.4 0.2 8.8e-05 22.4 0.2 3.7 5 0 0 5 5 5 1 N-terminal TM domain of oligopeptide transport permease C ABC2_membrane_4 PF12730.7 AAZ36682.1 - 7.5 6.5 13.4 0.051 13.5 3.8 2.2 3 0 0 3 3 3 0 ABC-2 family transporter protein Zn_peptidase PF04228.13 AAZ36683.1 - 1.3e-124 415.4 2.8 1.4e-124 415.3 2.8 1.0 1 0 0 1 1 1 1 Putative neutral zinc metallopeptidase DUF3152 PF11350.8 AAZ36683.1 - 0.028 14.1 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3152) Reprolysin_5 PF13688.6 AAZ36683.1 - 0.049 13.8 0.0 0.081 13.1 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Aspzincin_M35 PF14521.6 AAZ36683.1 - 0.058 13.9 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 Lysine-specific metallo-endopeptidase SoxG PF04268.12 AAZ36684.1 - 3.7e-52 176.4 0.0 4.4e-52 176.1 0.0 1.1 1 0 0 1 1 1 1 Sarcosine oxidase, gamma subunit family GCV_T PF01571.21 AAZ36684.1 - 4.3e-08 32.8 0.0 5.6e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain FAD_binding_4 PF01565.23 AAZ36685.1 - 7.6e-25 87.3 0.0 2e-24 85.9 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 AAZ36685.1 - 0.006 16.2 0.0 0.0099 15.5 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Response_reg PF00072.24 AAZ36686.1 - 7.8e-25 87.2 0.0 1e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain DUF1198 PF06711.11 AAZ36686.1 - 0.14 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1198) Peptidase_M4_C PF02868.15 AAZ36687.1 - 9.7e-46 155.7 0.0 1.3e-45 155.3 0.0 1.2 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.18 AAZ36687.1 - 7.9e-25 88.1 0.6 1.6e-24 87.1 0.6 1.5 1 0 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain PLN_propep PF16485.5 AAZ36687.1 - 0.2 11.4 0.0 0.4 10.4 0.0 1.5 1 0 0 1 1 1 0 Protealysin propeptide Ala_racemase_N PF01168.20 AAZ36688.1 - 8.5e-70 234.8 0.4 1.1e-69 234.5 0.4 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Ala_racemase_C PF00842.21 AAZ36688.1 - 1.2e-40 138.2 0.0 2e-40 137.4 0.0 1.4 1 0 0 1 1 1 1 Alanine racemase, C-terminal domain GNVR PF13807.6 AAZ36689.1 - 0.00039 20.3 0.0 0.0012 18.7 0.0 1.8 1 0 0 1 1 1 1 G-rich domain on putative tyrosine kinase Wzz PF02706.15 AAZ36689.1 - 0.0023 18.2 1.1 0.0078 16.5 0.0 2.4 2 0 0 2 2 2 1 Chain length determinant protein Bacillus_HBL PF05791.11 AAZ36689.1 - 0.0058 16.5 1.3 0.0058 16.5 1.3 3.0 2 1 0 3 3 3 1 Bacillus haemolytic enterotoxin (HBL) UPF0767 PF15990.5 AAZ36689.1 - 0.04 14.1 1.6 9.7 6.4 0.1 3.7 3 0 0 3 3 3 0 UPF0767 family MeaB PF03308.16 AAZ36689.1 - 0.061 12.3 0.5 0.32 9.9 0.1 2.2 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB dCMP_cyt_deam_2 PF08211.12 AAZ36689.1 - 0.079 13.2 0.1 0.2 11.9 0.1 1.7 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region DUF4407 PF14362.6 AAZ36689.1 - 0.31 10.3 18.2 0.17 11.2 10.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF4201 PF13870.6 AAZ36689.1 - 0.93 9.2 15.6 2.2 8.0 5.8 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) Phage_GP20 PF06810.11 AAZ36689.1 - 2.6 7.9 15.6 2.5 7.9 3.9 3.3 2 1 1 3 3 3 0 Phage minor structural protein GP20 DUF3970 PF13113.6 AAZ36689.1 - 3.1 8.1 4.4 1.7e+02 2.5 0.4 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3970) DUF5339 PF17274.2 AAZ36689.1 - 3.5 8.6 9.1 9.9 7.1 2.8 3.2 2 1 1 3 3 3 0 Family of unknown function (DUF5339) DUF4349 PF14257.6 AAZ36689.1 - 9.3 5.6 16.5 0.86 9.0 6.5 3.6 2 1 2 4 4 4 0 Domain of unknown function (DUF4349) Response_reg PF00072.24 AAZ36690.1 - 6.6e-26 90.7 0.0 8.9e-26 90.3 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAZ36690.1 - 7.8e-22 77.2 0.0 1.3e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal MarR_2 PF12802.7 AAZ36690.1 - 0.045 13.6 0.4 0.19 11.6 0.2 2.1 2 0 0 2 2 2 0 MarR family HTH_11 PF08279.12 AAZ36690.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 HTH domain GerE PF00196.19 AAZ36690.1 - 0.2 11.3 0.0 0.49 10.0 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family SPOR PF05036.13 AAZ36691.1 - 0.0043 17.4 0.1 0.0064 16.8 0.1 1.3 1 0 0 1 1 1 1 Sporulation related domain IMPDH PF00478.25 AAZ36692.1 - 1.1e-164 547.5 11.2 1.4e-164 547.2 11.2 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 AAZ36692.1 - 1.6e-13 50.9 2.4 2.1e-08 34.5 0.3 2.7 2 0 0 2 2 2 2 CBS domain NMO PF03060.15 AAZ36692.1 - 9.3e-11 41.7 21.7 1.3e-05 24.7 12.0 2.5 2 1 0 3 3 3 2 Nitronate monooxygenase FMN_dh PF01070.18 AAZ36692.1 - 2.7e-05 23.4 16.6 4e-05 22.8 10.5 3.3 4 1 1 5 5 5 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 AAZ36692.1 - 0.0018 17.8 7.2 0.19 11.2 0.2 3.1 2 1 1 3 3 3 2 Histidine biosynthesis protein Glu_synthase PF01645.17 AAZ36692.1 - 0.33 10.0 10.8 0.02 14.0 5.4 1.7 2 0 0 2 2 2 0 Conserved region in glutamate synthase DHO_dh PF01180.21 AAZ36692.1 - 0.5 9.5 12.8 0.084 12.1 1.7 3.0 2 1 1 3 3 3 0 Dihydroorotate dehydrogenase TMP-TENI PF02581.17 AAZ36692.1 - 0.61 9.4 5.8 0.5 9.7 2.6 2.3 1 1 0 2 2 2 0 Thiamine monophosphate synthase ThiG PF05690.14 AAZ36692.1 - 2.6 7.3 9.0 0.9 8.8 4.8 2.2 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG DrsE PF02635.15 AAZ36693.1 - 4e-18 65.9 0.0 4.4e-18 65.8 0.0 1.0 1 0 0 1 1 1 1 DsrE/DsrF-like family Peptidase_M19 PF01244.21 AAZ36694.1 - 1.4e-112 376.0 0.0 1.6e-112 375.8 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Polysacc_synt PF01943.17 AAZ36695.1 - 1.6e-11 44.1 13.8 1.6e-11 44.1 13.8 2.8 2 1 1 3 3 3 1 Polysaccharide biosynthesis protein Polysacc_synt_C PF14667.6 AAZ36695.1 - 3.6e-05 23.9 13.4 3.6e-05 23.9 13.4 3.8 3 1 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain NTP_transferase PF00483.23 AAZ36696.1 - 7e-20 71.6 0.0 2e-19 70.2 0.0 1.6 1 1 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AAZ36696.1 - 3.2e-09 37.3 0.0 4.2e-09 37.0 0.0 1.4 1 1 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 AAZ36696.1 - 0.014 15.2 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase UPF0767 PF15990.5 AAZ36696.1 - 0.064 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 UPF0767 family MotA_ExbB PF01618.16 AAZ36697.1 - 1.2e-34 118.8 0.5 1.6e-34 118.4 0.5 1.2 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family TetR_C_30 PF17939.1 AAZ36697.1 - 0.053 13.8 0.0 0.085 13.1 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Ribosomal_S9 PF00380.19 AAZ36697.1 - 0.073 13.6 0.1 0.11 13.0 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein S9/S16 HDPD PF02924.14 AAZ36697.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage lambda head decoration protein D SWIB PF02201.18 AAZ36697.1 - 0.18 11.7 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 SWIB/MDM2 domain DAO PF01266.24 AAZ36698.1 - 5e-16 59.2 1.2 6.7e-16 58.8 1.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AAZ36698.1 - 8.5e-07 28.4 2.1 1.5e-06 27.5 1.5 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 AAZ36698.1 - 3.1e-05 24.1 1.5 8.9e-05 22.6 1.4 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AAZ36698.1 - 4.7e-05 22.8 0.2 0.00019 20.8 0.2 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AAZ36698.1 - 8.2e-05 22.0 0.4 0.00015 21.2 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 AAZ36698.1 - 0.0018 17.6 0.5 0.0036 16.6 0.5 1.5 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 AAZ36698.1 - 0.0037 16.4 0.7 0.0082 15.2 0.2 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_oxidored PF12831.7 AAZ36698.1 - 0.015 14.7 1.2 0.02 14.3 1.2 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 AAZ36698.1 - 0.015 14.0 0.0 0.2 10.3 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein VWA_2 PF13519.6 AAZ36699.1 - 1.5e-10 41.6 0.6 3.3e-10 40.6 0.1 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain TPR_1 PF00515.28 AAZ36699.1 - 4.9e-07 29.3 3.1 1.3e-06 28.0 0.7 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 AAZ36699.1 - 9.4e-06 25.2 0.6 2.7e-05 23.8 0.6 1.9 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.17 AAZ36699.1 - 1.2e-05 25.0 10.3 1.5e-05 24.8 1.9 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 AAZ36699.1 - 2e-05 25.1 16.3 0.00014 22.5 4.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 AAZ36699.1 - 0.0003 21.3 2.5 0.0003 21.3 2.5 4.1 4 1 1 5 5 3 1 Tetratricopeptide repeat VWA PF00092.28 AAZ36699.1 - 0.00096 19.4 0.0 0.0016 18.7 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain TPR_9 PF13371.6 AAZ36699.1 - 0.0041 17.2 2.9 0.0041 17.2 2.9 2.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 AAZ36699.1 - 0.015 15.3 0.3 0.11 12.5 0.2 2.7 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 AAZ36699.1 - 0.02 15.0 0.1 0.047 13.9 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat BTAD PF03704.17 AAZ36699.1 - 0.11 13.0 10.6 9.2 6.7 0.7 3.1 2 1 1 3 3 3 0 Bacterial transcriptional activator domain TPR_6 PF13174.6 AAZ36699.1 - 0.14 12.9 1.9 0.48 11.2 0.3 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 AAZ36699.1 - 0.44 11.0 5.7 10 6.8 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 AAZ36699.1 - 1.7 9.2 11.0 0.41 11.2 2.1 3.6 3 1 1 4 4 3 0 Tetratricopeptide repeat Exosortase_EpsH PF09721.10 AAZ36699.1 - 2.9 7.3 12.3 0.16 11.4 5.9 1.9 2 0 0 2 2 2 0 Transmembrane exosortase (Exosortase_EpsH) DUF3659 PF12396.8 AAZ36700.1 - 0.0023 17.8 2.4 0.7 9.9 0.6 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3659) Tai4 PF16695.5 AAZ36701.1 - 1.5e-08 35.0 0.1 2e-08 34.7 0.1 1.2 1 0 0 1 1 1 1 Type VI secretion system (T6SS), amidase immunity protein ANTAR PF03861.14 AAZ36702.1 - 7.9e-15 54.4 6.5 1.6e-14 53.5 6.5 1.6 1 0 0 1 1 1 1 ANTAR domain Response_reg PF00072.24 AAZ36702.1 - 1.1e-06 28.8 0.1 2e-06 27.9 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain RcnB PF11776.8 AAZ36703.1 - 7.3e-08 32.3 1.4 1.6e-07 31.2 1.4 1.6 1 0 0 1 1 1 1 Nickel/cobalt transporter regulator Transposase_mut PF00872.18 AAZ36704.1 - 1.5e-117 392.7 0.0 1.9e-117 392.3 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ36704.1 - 7.7e-05 23.0 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain DUF4844 PF16133.5 AAZ36704.1 - 0.23 12.0 0.0 0.55 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) CN_hydrolase PF00795.22 AAZ36705.1 - 5.8e-54 183.2 0.0 6.6e-54 183.0 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF4096 PF13340.6 AAZ36706.1 - 5.8e-25 87.3 0.4 1.5e-24 86.0 0.4 1.8 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1 PF01609.21 AAZ36706.1 - 3.2e-14 53.1 0.0 5.7e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AAZ36706.1 - 7.2e-10 39.1 0.2 2.1e-09 37.6 0.2 1.9 1 0 0 1 1 1 1 Transposase DDE domain HTH_Tnp_Tc3_2 PF01498.18 AAZ36706.1 - 0.061 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Transposase Shikimate_dh_N PF08501.11 AAZ36707.1 - 1.7e-22 79.4 0.0 4.6e-22 78.1 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 AAZ36707.1 - 1.1e-05 25.1 0.1 2.3e-05 24.1 0.1 1.6 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 AAZ36707.1 - 0.0012 18.9 0.0 0.0022 18.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 AAZ36707.1 - 0.01 15.2 0.1 0.017 14.5 0.1 1.4 1 0 0 1 1 1 0 ThiF family Ribosomal_L29 PF00831.23 AAZ36708.1 - 2e-22 78.9 3.1 2.1e-22 78.8 3.1 1.0 1 0 0 1 1 1 1 Ribosomal L29 protein MRP-L47 PF06984.13 AAZ36708.1 - 0.0012 18.9 0.8 0.0016 18.5 0.8 1.2 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) YjcZ PF13990.6 AAZ36708.1 - 0.05 13.0 0.6 0.046 13.1 0.6 1.0 1 0 0 1 1 1 0 YjcZ-like protein Peptidase_M17_N PF02789.17 AAZ36708.1 - 0.091 12.6 0.1 0.11 12.3 0.1 1.1 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain DUF3772 PF12607.8 AAZ36708.1 - 0.17 11.7 2.2 0.5 10.2 2.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3772) UreD PF01774.17 AAZ36709.1 - 2.9e-51 174.4 0.0 3.4e-51 174.2 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein FTSW_RODA_SPOVE PF01098.19 AAZ36710.1 - 8.7e-103 344.1 28.1 1.1e-102 343.7 28.1 1.0 1 0 0 1 1 1 1 Cell cycle protein Gln-synt_C PF00120.24 AAZ36711.1 - 1.4e-103 346.5 0.0 1.7e-103 346.3 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 AAZ36711.1 - 0.01 15.6 0.0 0.13 12.1 0.0 2.2 1 1 0 1 1 1 0 Glutamine synthetase N-terminal domain BPD_transp_1 PF00528.22 AAZ36712.1 - 1.8e-27 96.3 11.8 1.8e-27 96.3 11.8 1.6 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component T3SS_basalb_I PF17001.5 AAZ36713.1 - 7.1e-17 61.8 1.2 8.8e-17 61.5 1.2 1.1 1 0 0 1 1 1 1 Type III secretion basal body protein I, YscI, HrpB, PscI RestrictionSfiI PF11487.8 AAZ36713.1 - 0.09 12.6 0.1 0.11 12.4 0.1 1.1 1 0 0 1 1 1 0 Type II restriction enzyme SfiI DUF3726 PF12525.8 AAZ36713.1 - 0.12 12.5 0.1 0.2 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3726) Abhydrolase_1 PF00561.20 AAZ36714.1 - 6.5e-08 32.5 0.1 0.00055 19.7 0.0 2.9 1 1 0 2 2 2 2 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 AAZ36714.1 - 1.9e-05 23.7 0.0 6.6e-05 21.9 0.0 1.8 2 0 0 2 2 2 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 AAZ36714.1 - 7e-05 22.2 0.6 0.4 9.9 0.0 2.6 1 1 0 2 2 2 2 Serine aminopeptidase, S33 PAF-AH_p_II PF03403.13 AAZ36714.1 - 9.3e-05 21.1 0.0 0.0011 17.6 0.0 2.1 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II BAAT_C PF08840.11 AAZ36714.1 - 0.00013 21.9 0.0 0.13 12.1 0.0 2.1 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 AAZ36714.1 - 0.0018 17.9 0.0 0.11 12.0 0.0 2.6 2 1 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 AAZ36714.1 - 0.0098 15.4 0.2 0.055 12.9 0.0 2.1 2 1 0 2 2 2 1 Prolyl oligopeptidase family Esterase PF00756.20 AAZ36714.1 - 0.031 13.9 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Glyco_trans_4_5 PF16994.5 AAZ36714.1 - 0.033 13.8 0.0 0.084 12.5 0.0 1.7 2 0 0 2 2 2 0 Glycosyl-transferase family 4 Chlorophyllase PF07224.11 AAZ36714.1 - 0.042 12.9 0.1 0.14 11.1 0.1 1.8 1 1 0 1 1 1 0 Chlorophyllase FSH1 PF03959.13 AAZ36714.1 - 0.059 13.0 0.0 0.14 11.8 0.0 1.5 1 1 0 1 1 1 0 Serine hydrolase (FSH1) PqqD PF05402.12 AAZ36715.1 - 9.6e-14 51.4 0.0 1.1e-13 51.2 0.0 1.1 1 0 0 1 1 1 1 Coenzyme PQQ synthesis protein D (PqqD) CxxCxxCC PF03692.15 AAZ36716.1 - 2e-14 54.0 2.8 3e-14 53.5 2.8 1.3 1 0 0 1 1 1 1 Putative zinc- or iron-chelating domain FlaE PF07559.14 AAZ36717.1 - 2.9e-20 73.1 16.4 2.9e-20 73.1 16.4 3.9 3 1 0 3 3 3 1 Flagellar basal body protein FlaE Flg_bbr_C PF06429.13 AAZ36717.1 - 3.6e-15 55.9 1.5 3.6e-15 55.9 1.5 3.3 4 0 0 4 4 4 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 AAZ36717.1 - 1.4e-08 34.5 1.5 1.4e-08 34.5 1.5 3.7 3 0 0 3 3 3 1 Flagella basal body rod protein PepSY_TM PF03929.16 AAZ36718.1 - 5e-76 256.1 11.4 6.8e-76 255.7 11.4 1.2 1 0 0 1 1 1 1 PepSY-associated TM region PepSY PF03413.19 AAZ36718.1 - 1.2e-12 48.2 0.2 1.6e-05 25.4 0.1 2.3 2 0 0 2 2 2 2 Peptidase propeptide and YPEB domain DUF4405 PF14358.6 AAZ36718.1 - 0.0019 18.7 6.0 0.0019 18.7 6.0 4.0 3 1 0 3 3 3 1 Domain of unknown function (DUF4405) Ni_hydr_CYTB PF01292.20 AAZ36718.1 - 0.021 14.4 21.8 0.023 14.3 2.9 4.4 3 2 1 4 4 4 0 Prokaryotic cytochrome b561 HSP70 PF00012.20 AAZ36719.1 - 1.8e-31 109.1 0.0 4.6e-12 44.9 0.0 3.0 2 1 1 3 3 3 3 Hsp70 protein MreB_Mbl PF06723.13 AAZ36719.1 - 5e-07 28.8 0.0 9.4e-06 24.7 0.0 2.5 3 0 0 3 3 3 1 MreB/Mbl protein StbA PF06406.11 AAZ36719.1 - 0.0013 18.0 0.1 0.0048 16.2 0.0 1.8 2 0 0 2 2 2 1 StbA protein Hydantoinase_A PF01968.18 AAZ36719.1 - 0.013 14.8 0.1 3.8 6.7 0.0 2.2 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase MutL PF13941.6 AAZ36719.1 - 0.058 12.0 0.0 3.8 6.0 0.0 2.1 2 0 0 2 2 2 0 MutL protein DEAD PF00270.29 AAZ36720.1 - 1.4e-48 165.0 0.0 7.6e-47 159.3 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AAZ36720.1 - 7.5e-28 97.1 0.0 2.4e-27 95.5 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 AAZ36720.1 - 8.4e-07 29.1 0.0 5.3e-06 26.6 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 AAZ36720.1 - 0.046 14.0 0.0 1.3 9.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 AAZ36720.1 - 0.054 13.8 0.5 0.87 9.9 0.5 2.3 1 1 0 1 1 1 0 AAA domain Transposase_mut PF00872.18 AAZ36721.1 - 1.5e-117 392.7 0.0 1.9e-117 392.3 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ36721.1 - 7.7e-05 23.0 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain DUF4844 PF16133.5 AAZ36721.1 - 0.23 12.0 0.0 0.55 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) MCPsignal PF00015.21 AAZ36722.1 - 1.7e-40 138.6 39.7 8.1e-40 136.4 21.5 3.4 2 1 1 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AAZ36722.1 - 2.3e-09 37.5 3.3 8.1e-09 35.7 0.0 3.6 4 0 0 4 4 3 1 HAMP domain 4HB_MCP_1 PF12729.7 AAZ36722.1 - 1.4e-05 24.7 0.0 1.4e-05 24.7 0.0 4.7 4 2 2 6 6 6 1 Four helix bundle sensory module for signal transduction DUF948 PF06103.11 AAZ36722.1 - 0.0023 18.2 34.7 0.63 10.3 7.0 6.5 3 2 2 5 5 5 2 Bacterial protein of unknown function (DUF948) DUF4307 PF14155.6 AAZ36722.1 - 0.01 15.7 0.7 0.3 10.9 0.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) CHASE3 PF05227.13 AAZ36722.1 - 0.019 14.9 1.8 0.019 14.9 1.8 4.7 3 1 0 4 4 4 0 CHASE3 domain DUF1664 PF07889.12 AAZ36722.1 - 0.03 14.3 0.8 0.03 14.3 0.8 5.1 3 1 2 6 6 5 0 Protein of unknown function (DUF1664) Spore_III_AB PF09548.10 AAZ36722.1 - 0.066 13.3 5.0 0.074 13.2 0.1 3.2 3 1 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) DIRP PF06584.13 AAZ36722.1 - 0.095 12.9 0.1 0.4 10.9 0.0 2.1 2 0 0 2 2 1 0 DIRP YrvL PF14184.6 AAZ36722.1 - 0.23 11.6 0.1 0.23 11.6 0.1 1.7 2 0 0 2 2 2 0 Regulatory protein YrvL Glycophorin_A PF01102.18 AAZ36722.1 - 0.26 11.5 0.0 0.26 11.5 0.0 3.3 3 0 0 3 3 3 0 Glycophorin A LINES_N PF14694.6 AAZ36722.1 - 0.64 9.4 6.9 1.4 8.3 0.4 3.1 3 1 0 3 3 3 0 Lines N-terminus Vps54_N PF10475.9 AAZ36722.1 - 3.7 6.7 10.8 2.3 7.4 8.2 2.0 1 1 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex PIN_8 PF18476.1 AAZ36722.1 - 4 7.2 19.2 0.27 11.1 4.3 2.9 4 0 0 4 4 4 0 PIN like domain Peripla_BP_5 PF13433.6 AAZ36723.1 - 5.4e-142 473.1 0.0 6.4e-142 472.8 0.0 1.0 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_6 PF13458.6 AAZ36723.1 - 1.6e-64 218.8 0.0 1.8e-64 218.6 0.0 1.0 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 AAZ36723.1 - 0.00071 18.8 0.0 0.7 8.9 0.0 2.1 2 0 0 2 2 2 2 Receptor family ligand binding region BPD_transp_1 PF00528.22 AAZ36724.1 - 2.4e-35 122.0 9.5 2.4e-35 122.0 9.5 1.7 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Response_reg PF00072.24 AAZ36725.1 - 1.1e-09 38.5 0.0 2.3e-09 37.4 0.0 1.5 1 1 0 1 1 1 1 Response regulator receiver domain MFS_1 PF07690.16 AAZ36726.1 - 2.3e-35 122.1 61.9 5.3e-24 84.8 30.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DAO PF01266.24 AAZ36727.1 - 1.8e-59 202.1 0.1 2.1e-59 201.9 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AAZ36727.1 - 7.2e-06 25.3 4.4 3.9e-05 22.9 4.4 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 AAZ36727.1 - 1.3e-05 24.6 0.7 0.013 14.7 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AAZ36727.1 - 7.2e-05 22.9 1.3 0.00017 21.8 0.9 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 AAZ36727.1 - 9.6e-05 21.7 1.3 0.00024 20.4 0.1 1.9 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 AAZ36727.1 - 0.00052 19.4 0.9 0.018 14.3 0.3 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AAZ36727.1 - 0.00077 18.8 0.3 0.047 12.9 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 AAZ36727.1 - 0.0018 18.8 1.1 0.72 10.5 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AAZ36727.1 - 0.012 15.0 1.5 0.024 14.0 1.5 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 AAZ36727.1 - 0.012 14.5 0.5 0.1 11.4 0.3 2.0 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.14 AAZ36727.1 - 0.019 13.7 2.6 1.2 7.7 0.2 2.2 2 0 0 2 2 2 0 HI0933-like protein UbiA PF01040.18 AAZ36728.1 - 4e-25 88.6 20.0 6.2e-25 87.9 20.0 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family HAD PF12710.7 AAZ36728.1 - 2.6e-06 28.0 2.1 0.00025 21.5 1.5 3.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AAZ36728.1 - 0.26 11.0 1.0 20 4.8 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF2534 PF10749.9 AAZ36728.1 - 1.2 9.4 4.8 6.6 7.0 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2534) HTH_18 PF12833.7 AAZ36729.1 - 2.6e-24 85.3 0.1 3.7e-24 84.8 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAZ36729.1 - 6e-13 48.5 0.0 2.5e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_24 PF13412.6 AAZ36729.1 - 1.2e-06 28.0 0.0 0.0002 20.9 0.0 2.4 2 1 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 AAZ36729.1 - 1.7e-06 27.8 0.1 2.8e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 HTH domain HTH_29 PF13551.6 AAZ36729.1 - 0.00031 20.7 0.0 0.02 14.9 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn helix HTH_AsnC-type PF13404.6 AAZ36729.1 - 0.00044 20.0 0.1 0.0019 18.0 0.1 2.0 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_23 PF13384.6 AAZ36729.1 - 0.0014 18.4 0.0 0.094 12.5 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_20 PF12840.7 AAZ36729.1 - 0.0018 18.3 0.2 0.0037 17.3 0.1 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 AAZ36729.1 - 0.009 15.7 0.0 0.077 12.7 0.0 2.1 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 AAZ36729.1 - 0.013 15.4 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 ECF sigma factor HTH_31 PF13560.6 AAZ36729.1 - 0.014 15.7 0.0 0.14 12.5 0.0 2.4 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 AAZ36729.1 - 0.016 15.2 0.1 0.025 14.6 0.1 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_17 PF12728.7 AAZ36729.1 - 0.021 15.0 0.0 0.04 14.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain MarR_2 PF12802.7 AAZ36729.1 - 0.022 14.6 0.0 0.073 13.0 0.0 1.8 2 0 0 2 2 2 0 MarR family HTH_Tnp_ISL3 PF13542.6 AAZ36729.1 - 0.025 14.0 0.0 2.4 7.7 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 B-block_TFIIIC PF04182.12 AAZ36729.1 - 0.028 14.6 0.0 0.031 14.4 0.0 1.2 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC DUF2802 PF10975.8 AAZ36729.1 - 0.036 14.2 0.1 1.9 8.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) HTH_8 PF02954.19 AAZ36729.1 - 0.057 13.2 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family GerE PF00196.19 AAZ36729.1 - 0.079 12.5 0.0 0.37 10.4 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family TetR_N PF00440.23 AAZ36729.1 - 0.082 12.7 0.0 0.68 9.8 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family Sigma70_r4 PF04545.16 AAZ36729.1 - 0.11 12.1 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_26 PF13443.6 AAZ36729.1 - 0.11 12.9 0.1 0.26 11.8 0.1 1.7 1 1 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain MarR PF01047.22 AAZ36729.1 - 0.12 12.4 0.1 0.25 11.3 0.1 1.6 1 1 0 1 1 1 0 MarR family Peripla_BP_4 PF13407.6 AAZ36730.1 - 1e-57 195.7 14.5 1.2e-57 195.4 14.5 1.0 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 AAZ36730.1 - 3.8e-19 69.2 2.0 4.6e-19 68.9 2.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_3 PF13377.6 AAZ36730.1 - 1.6e-07 31.8 0.1 3.7e-07 30.6 0.0 1.8 1 1 1 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_6 PF13458.6 AAZ36730.1 - 4.3e-06 26.6 8.3 1.9e-05 24.5 8.3 1.9 1 1 0 1 1 1 1 Periplasmic binding protein PucR PF07905.11 AAZ36730.1 - 0.082 13.2 0.1 0.33 11.2 0.0 1.9 2 0 0 2 2 2 0 Purine catabolism regulatory protein-like family OmpA PF00691.20 AAZ36731.1 - 3.5e-24 85.0 0.0 5e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 OmpA family SDH_alpha PF03313.15 AAZ36733.1 - 1.1e-100 336.6 6.1 1.4e-100 336.3 6.1 1.1 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 AAZ36733.1 - 1.1e-55 188.2 0.0 2.7e-55 187.0 0.0 1.6 2 0 0 2 2 2 1 Serine dehydratase beta chain MmgE_PrpD PF03972.14 AAZ36733.1 - 0.024 13.2 3.1 0.041 12.4 3.1 1.3 1 0 0 1 1 1 0 MmgE/PrpD family Serine_rich PF08824.10 AAZ36733.1 - 0.071 13.1 0.2 0.29 11.1 0.2 2.0 2 0 0 2 2 2 0 Serine rich protein interaction domain Sigma70_ner PF04546.13 AAZ36734.1 - 4.7e-58 196.4 0.0 4.7e-58 196.4 0.0 3.0 3 1 0 3 3 3 1 Sigma-70, non-essential region Sigma70_r3 PF04539.16 AAZ36734.1 - 1.6e-30 105.0 2.3 1.7e-29 101.8 0.9 3.1 2 0 0 2 2 2 1 Sigma-70 region 3 Sigma70_r1_1 PF03979.14 AAZ36734.1 - 8.4e-29 99.5 2.0 8.4e-29 99.5 2.0 2.6 2 0 0 2 2 2 1 Sigma-70 factor, region 1.1 Sigma70_r2 PF04542.14 AAZ36734.1 - 8.8e-22 76.7 0.3 1.8e-21 75.6 0.3 1.6 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 AAZ36734.1 - 1.2e-19 69.6 9.8 1.6e-18 66.0 0.8 3.8 3 0 0 3 3 3 2 Sigma-70, region 4 Sigma70_r1_2 PF00140.20 AAZ36734.1 - 1.2e-13 50.8 2.1 4.8e-13 48.9 1.2 2.5 2 0 0 2 2 2 1 Sigma-70 factor, region 1.2 TMPIT PF07851.13 AAZ36734.1 - 0.02 14.2 0.1 0.037 13.3 0.1 1.4 1 0 0 1 1 1 0 TMPIT-like protein NDK PF00334.19 AAZ36735.1 - 6.6e-53 178.3 0.1 7.3e-53 178.2 0.1 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase BPD_transp_1 PF00528.22 AAZ36736.1 - 6.9e-20 71.6 13.8 1.1e-19 70.9 13.8 1.2 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component DUF5531 PF17671.1 AAZ36736.1 - 0.33 10.8 2.3 0.42 10.5 0.2 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5531) Ribosomal_L11_N PF03946.14 AAZ36737.1 - 1.1e-30 105.2 0.2 2e-30 104.4 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 AAZ36737.1 - 1.4e-23 83.2 0.9 2.1e-23 82.6 0.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain SBP_bac_3 PF00497.20 AAZ36738.1 - 1.2e-09 38.0 0.0 1.4e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.7 AAZ36738.1 - 0.00093 18.9 0.2 0.011 15.3 0.0 2.0 1 1 0 2 2 2 1 ABC transporter, phosphonate, periplasmic substrate-binding protein Smoa_sbd PF17885.1 AAZ36738.1 - 0.018 15.1 0.0 0.12 12.5 0.0 2.1 2 0 0 2 2 2 0 Styrene monooxygenase A putative substrate binding domain Fer2_4 PF13510.6 AAZ36740.1 - 1.2e-21 76.5 0.1 1.5e-21 76.3 0.1 1.0 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DsbB PF02600.16 AAZ36741.1 - 3.4e-36 124.9 11.6 4e-36 124.7 11.6 1.0 1 0 0 1 1 1 1 Disulfide bond formation protein DsbB PrgI PF12666.7 AAZ36741.1 - 9.8 7.0 7.9 8 7.3 2.9 2.3 2 0 0 2 2 2 0 PrgI family protein DUF1722 PF08349.11 AAZ36742.1 - 1.7e-41 141.1 0.5 2.7e-41 140.5 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1722) DUF523 PF04463.12 AAZ36742.1 - 1.4e-34 119.1 0.1 2.6e-34 118.2 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF523) PSD2 PF07624.11 AAZ36742.1 - 0.08 12.7 0.1 1.6 8.6 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1585) TM2 PF05154.16 AAZ36743.1 - 9.9e-30 102.6 31.4 5e-16 58.8 11.3 2.1 2 0 0 2 2 2 2 TM2 domain HDOD PF08668.12 AAZ36744.1 - 3.6e-46 157.1 0.0 5.2e-46 156.6 0.0 1.2 1 0 0 1 1 1 1 HDOD domain tRNA_edit PF04073.15 AAZ36744.1 - 1e-12 48.2 0.0 1.8e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain Aminotran_3 PF00202.21 AAZ36745.1 - 3.7e-51 174.1 0.0 8.6e-51 172.9 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-III Mn_catalase PF05067.12 AAZ36746.1 - 9.7e-97 323.3 0.0 1.1e-96 323.2 0.0 1.0 1 0 0 1 1 1 1 Manganese containing catalase COQ7 PF03232.13 AAZ36746.1 - 0.0038 17.0 0.0 1 9.1 0.0 2.2 2 0 0 2 2 2 2 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 AAZ36746.1 - 0.073 13.5 0.0 3.3 8.1 0.0 2.2 2 0 0 2 2 2 0 Rubrerythrin Arginosuc_synth PF00764.19 AAZ36747.1 - 1.7e-154 514.8 0.0 1.9e-154 514.6 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 AAZ36747.1 - 0.00095 18.7 0.0 0.0019 17.8 0.0 1.4 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 AAZ36747.1 - 0.0021 17.8 0.0 0.0032 17.2 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase GST_N_3 PF13417.6 AAZ36748.1 - 1.1e-09 38.5 0.0 2.1e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 AAZ36748.1 - 2.4e-05 24.3 0.3 0.00012 22.1 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 AAZ36748.1 - 0.0014 18.8 0.0 0.01 16.0 0.0 2.1 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 AAZ36748.1 - 0.0019 18.5 0.0 0.0038 17.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Bac_export_1 PF01311.20 AAZ36749.1 - 5.7e-49 166.8 30.7 6.6e-49 166.5 30.7 1.0 1 0 0 1 1 1 1 Bacterial export proteins, family 1 Bac_DNA_binding PF00216.21 AAZ36750.1 - 3.3e-32 110.5 0.0 3.6e-32 110.4 0.0 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 AAZ36750.1 - 9.8e-06 25.7 0.0 9.8e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_bac_2 PF18175.1 AAZ36750.1 - 0.0041 17.0 0.0 0.0063 16.4 0.0 1.2 1 0 0 1 1 1 1 CCDC81-like prokaryotic HU domain 2 HU-CCDC81_euk_1 PF14908.6 AAZ36750.1 - 0.025 14.7 0.0 0.026 14.7 0.0 1.1 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 1 HU-CCDC81_bac_1 PF18174.1 AAZ36750.1 - 0.084 12.8 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 1 DUF4115 PF13464.6 AAZ36751.1 - 3e-26 91.4 0.1 1.1e-25 89.6 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4115) HTH_25 PF13413.6 AAZ36751.1 - 3.4e-20 71.7 0.0 7.1e-20 70.6 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 AAZ36751.1 - 8.3e-07 29.3 0.1 1.8e-06 28.2 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 AAZ36751.1 - 2.6e-06 27.4 0.0 4.1e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 AAZ36751.1 - 0.00024 21.1 0.0 0.00056 19.9 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix HTH_37 PF13744.6 AAZ36751.1 - 0.011 15.7 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DUF4813 PF16072.5 AAZ36751.1 - 2.2 7.9 31.3 3.3 7.3 31.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) HxlR PF01638.17 AAZ36752.1 - 4.4e-19 68.1 0.0 6.5e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 HxlR-like helix-turn-helix PepSY_TM PF03929.16 AAZ36753.1 - 1.9e-57 195.1 10.8 2.3e-57 194.8 10.8 1.0 1 0 0 1 1 1 1 PepSY-associated TM region PepSY_TM_like_2 PF16357.5 AAZ36753.1 - 0.00099 19.1 1.0 0.0019 18.2 0.0 1.9 2 1 0 2 2 2 1 Putative PepSY_TM-like DUF4405 PF14358.6 AAZ36753.1 - 0.059 13.9 0.3 0.059 13.9 0.3 3.9 3 2 1 4 4 4 0 Domain of unknown function (DUF4405) Ni_hydr_CYTB PF01292.20 AAZ36753.1 - 0.13 11.9 8.9 0.06 12.9 1.6 3.1 3 0 0 3 3 3 0 Prokaryotic cytochrome b561 DUF1129 PF06570.11 AAZ36753.1 - 6.9 6.1 6.5 0.9 9.0 1.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) SLT_2 PF13406.6 AAZ36754.1 - 2.8e-103 345.2 0.0 3.1e-103 345.0 0.0 1.0 1 0 0 1 1 1 1 Transglycosylase SLT domain SLT PF01464.20 AAZ36754.1 - 0.0014 18.3 0.0 0.0083 15.8 0.0 2.1 1 1 0 1 1 1 1 Transglycosylase SLT domain HemolysinCabind PF00353.19 AAZ36755.1 - 0 1406.9 1372.4 1.6e-12 47.1 8.0 73.9 31 22 59 95 95 95 94 RTX calcium-binding nonapeptide repeat (4 copies) HCBP_related PF06594.11 AAZ36755.1 - 5.9e-290 935.1 127.8 1.3e-12 47.5 0.2 26.8 25 0 0 25 25 25 25 Haemolysin-type calcium binding protein related domain ArsA_HSP20 PF17886.1 AAZ36755.1 - 3.7e-19 68.0 55.3 5 6.8 0.0 21.0 23 0 0 23 23 23 12 HSP20-like domain found in ArsA RTX_C PF08339.10 AAZ36755.1 - 2.8e-13 50.3 0.9 0.028 14.5 0.1 12.9 18 0 0 18 18 18 2 RTX C-terminal domain PepSY_2 PF13670.6 AAZ36755.1 - 0.013 15.5 8.4 76 3.4 0.0 7.5 7 0 0 7 7 7 0 Peptidase propeptide and YPEB domain DUF2061 PF09834.9 AAZ36755.1 - 0.12 12.9 2.3 31 5.2 0.1 4.1 4 0 0 4 4 4 0 Predicted membrane protein (DUF2061) Thiolase_N PF00108.23 AAZ36757.1 - 5.5e-48 163.6 0.0 7.7e-48 163.1 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 AAZ36757.1 - 4.4e-37 126.5 0.6 4.4e-37 126.5 0.6 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 AAZ36757.1 - 0.0065 16.3 0.9 1.9 8.4 0.0 2.6 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Peripla_BP_2 PF01497.18 AAZ36758.1 - 2.6e-22 79.6 0.0 3.5e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein MraZ PF02381.18 AAZ36758.1 - 0.18 11.8 0.0 2.3 8.3 0.0 2.3 2 0 0 2 2 2 0 MraZ protein, putative antitoxin-like AA_kinase PF00696.28 AAZ36759.1 - 3e-43 148.2 3.8 3.6e-43 147.9 3.8 1.1 1 0 0 1 1 1 1 Amino acid kinase family XPG_N PF00752.17 AAZ36759.1 - 0.052 14.0 0.0 0.095 13.2 0.0 1.4 1 0 0 1 1 1 0 XPG N-terminal domain Transcrip_reg PF01709.20 AAZ36760.1 - 4.1e-68 229.4 0.0 4.7e-68 229.2 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator OEP PF02321.18 AAZ36761.1 - 6.5e-56 189.1 31.0 6e-30 104.5 6.1 2.0 2 0 0 2 2 2 2 Outer membrane efflux protein ParE_toxin PF05016.15 AAZ36761.1 - 0.084 13.5 0.3 15 6.3 0.2 2.6 2 0 0 2 2 2 0 ParE toxin of type II toxin-antitoxin system, parDE CCP_MauG PF03150.14 AAZ36761.1 - 0.17 12.5 2.3 4.7 7.8 0.1 3.0 2 1 1 3 3 3 0 Di-haem cytochrome c peroxidase Yae1_N PF09811.9 AAZ36762.1 - 0.17 11.6 1.1 0.68 9.7 0.3 2.2 2 0 0 2 2 2 0 Essential protein Yae1, N terminal SRP54 PF00448.22 AAZ36763.1 - 1.1e-46 159.0 0.0 1.5e-46 158.5 0.0 1.1 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain FtsK_SpoIIIE PF01580.18 AAZ36763.1 - 6.5e-05 22.4 0.0 0.0001 21.7 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_22 PF13401.6 AAZ36763.1 - 0.00015 22.1 0.0 0.00045 20.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AAZ36763.1 - 0.00089 19.0 1.2 0.015 15.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 AAZ36763.1 - 0.0036 17.3 0.0 0.0068 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 AAZ36763.1 - 0.01 16.4 0.0 0.02 15.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 AAZ36763.1 - 0.012 16.0 1.2 0.15 12.4 0.6 2.6 1 1 1 2 2 2 0 AAA ATPase domain Terminase_6 PF03237.15 AAZ36763.1 - 0.014 15.0 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Terminase-like family AAA_28 PF13521.6 AAZ36763.1 - 0.016 15.4 0.0 0.035 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AAZ36763.1 - 0.017 15.3 0.1 0.041 14.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 AAZ36763.1 - 0.02 14.8 0.0 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 AAZ36763.1 - 0.022 15.2 0.1 0.086 13.3 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 AAZ36763.1 - 0.024 14.2 0.0 0.052 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 AAZ36763.1 - 0.035 14.5 0.0 0.074 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 AAZ36763.1 - 0.056 13.4 0.0 0.099 12.6 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CbiA PF01656.23 AAZ36763.1 - 0.11 12.6 0.1 8 6.5 0.1 2.4 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain RsgA_GTPase PF03193.16 AAZ36763.1 - 0.11 12.4 0.0 0.33 10.9 0.0 1.7 1 1 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 AAZ36763.1 - 0.15 12.2 0.0 0.37 10.9 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.14 AAZ36763.1 - 0.18 11.8 0.3 1.9 8.5 0.3 2.2 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 AAZ36763.1 - 0.2 11.3 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Pyocin_S PF06958.12 AAZ36764.1 - 1.4e-28 100.2 2.1 2.5e-28 99.3 2.1 1.4 1 0 0 1 1 1 1 S-type Pyocin UPF0242 PF06785.11 AAZ36764.1 - 0.64 10.1 2.4 1.1 9.4 2.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus YfiO PF13525.6 AAZ36765.1 - 0.0064 16.2 1.3 0.015 15.0 1.3 1.7 1 1 0 1 1 1 1 Outer membrane lipoprotein TPR_6 PF13174.6 AAZ36765.1 - 0.0071 16.9 0.1 0.022 15.4 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_18 PF13512.6 AAZ36765.1 - 0.0073 16.4 1.4 0.051 13.7 0.4 2.1 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 AAZ36765.1 - 0.01 16.5 1.9 0.025 15.2 0.0 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4006 PF13179.6 AAZ36765.1 - 0.15 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF4006) PP-binding PF00550.25 AAZ36766.1 - 1.6e-09 38.0 0.6 2.3e-09 37.5 0.6 1.4 1 1 0 1 1 1 1 Phosphopantetheine attachment site Methyltrans_RNA PF04452.14 AAZ36767.1 - 1.2e-43 149.1 0.0 1.3e-43 149.0 0.0 1.0 1 0 0 1 1 1 1 RNA methyltransferase PfkB PF00294.24 AAZ36768.1 - 2e-38 132.4 0.0 2.3e-38 132.2 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase MR_MLE_C PF13378.6 AAZ36769.1 - 6.9e-51 172.9 0.0 1.1e-50 172.2 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 AAZ36769.1 - 1.3e-09 38.3 0.0 3.6e-09 36.8 0.0 1.8 2 1 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 4HBT PF03061.22 AAZ36770.1 - 4.3e-20 71.8 0.3 6.1e-20 71.4 0.3 1.2 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 AAZ36770.1 - 1.9e-11 44.2 0.0 2.3e-11 44.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) 4HBT_3 PF13622.6 AAZ36770.1 - 2.3e-07 31.4 0.2 2.6e-07 31.1 0.2 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily YiiD_C PF09500.10 AAZ36770.1 - 0.0067 16.3 0.0 0.13 12.1 0.0 2.1 1 1 0 1 1 1 1 Putative thioesterase (yiiD_Cterm) ABC_trans_aux PF03886.13 AAZ36771.1 - 4.9e-41 140.0 0.0 5.9e-41 139.7 0.0 1.1 1 0 0 1 1 1 1 ABC-type transport auxiliary lipoprotein component AAA_30 PF13604.6 AAZ36772.1 - 1e-30 106.9 2.1 4.9e-30 104.7 0.2 2.2 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.6 AAZ36772.1 - 5.9e-27 94.8 0.1 1.5e-26 93.5 0.1 1.7 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 AAZ36772.1 - 1.2e-15 57.0 0.0 3e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Helicase_RecD PF05127.14 AAZ36772.1 - 7.4e-14 52.0 0.0 1.3e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Helicase AAA_11 PF13086.6 AAZ36772.1 - 4.4e-11 43.1 1.1 2.5e-06 27.5 0.1 2.3 1 1 1 2 2 2 2 AAA domain SH3_13 PF18335.1 AAZ36772.1 - 2.2e-08 33.8 0.0 4e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent RecD-like DNA helicase SH3 domain AAA_22 PF13401.6 AAZ36772.1 - 7.2e-08 32.8 0.0 1.7e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 AAZ36772.1 - 3.3e-06 27.0 1.8 0.044 13.5 0.0 3.3 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 AAZ36772.1 - 0.0039 17.6 0.2 0.0039 17.6 0.2 3.0 4 0 0 4 4 3 1 AAA ATPase domain DUF2075 PF09848.9 AAZ36772.1 - 0.0048 16.2 0.0 0.0083 15.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 AAZ36772.1 - 0.0061 16.1 0.0 0.0096 15.5 0.0 1.3 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain PhoH PF02562.16 AAZ36772.1 - 0.0094 15.4 0.1 0.04 13.4 0.1 2.0 1 1 0 1 1 1 1 PhoH-like protein AAA_28 PF13521.6 AAZ36772.1 - 0.01 16.1 0.2 0.034 14.4 0.2 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 AAZ36772.1 - 0.029 14.3 0.0 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 NACHT domain T2SSE PF00437.20 AAZ36772.1 - 0.03 13.4 0.0 0.05 12.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NTPase_1 PF03266.15 AAZ36772.1 - 0.035 14.0 0.6 0.096 12.6 0.3 1.8 2 0 0 2 2 2 0 NTPase AAA_5 PF07728.14 AAZ36772.1 - 0.042 13.9 0.2 0.3 11.1 0.2 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 AAZ36772.1 - 0.049 14.1 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain UvrD_C PF13361.6 AAZ36772.1 - 0.076 12.4 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_18 PF13238.6 AAZ36772.1 - 0.1 13.1 0.0 1.8 9.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain GspH PF12019.8 AAZ36773.1 - 0.012 16.0 0.0 0.017 15.6 0.0 1.3 1 1 0 1 1 1 0 Type II transport protein GspH LapD_MoxY_N PF16448.5 AAZ36773.1 - 0.077 12.9 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 LapD/MoxY periplasmic domain N_methyl PF07963.12 AAZ36773.1 - 2.4 7.8 6.7 4.5 7.0 6.7 1.5 1 0 0 1 1 1 0 Prokaryotic N-terminal methylation motif ChaC PF04752.12 AAZ36774.1 - 5.7e-38 130.7 0.0 6.7e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein DEAD_assoc PF08494.11 AAZ36775.1 - 4.1e-49 167.0 1.3 9e-49 165.9 0.5 2.0 2 0 0 2 2 2 1 DEAD/H associated DEAD PF00270.29 AAZ36775.1 - 9.3e-22 77.6 0.0 1.6e-21 76.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AAZ36775.1 - 4.4e-11 43.1 0.0 8.1e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 AAZ36775.1 - 2.9e-05 24.2 0.0 4.9e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UPF0016 PF01169.19 AAZ36776.1 - 7.4e-42 141.5 21.4 1.3e-21 76.7 7.0 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TauE PF01925.19 AAZ36776.1 - 0.0018 17.9 15.1 0.0045 16.7 1.9 2.2 1 1 1 2 2 2 2 Sulfite exporter TauE/SafE Ribosomal_S19 PF00203.21 AAZ36777.1 - 5.9e-35 119.0 0.1 6.6e-35 118.8 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19 DUF1442 PF07279.11 AAZ36777.1 - 0.028 13.7 0.0 0.031 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1442) Glyoxalase_5 PF14696.6 AAZ36778.1 - 5e-71 237.3 0.0 1.3e-70 236.0 0.0 1.7 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase PF00903.25 AAZ36778.1 - 8.6e-23 80.9 0.0 1.8e-19 70.2 0.1 2.2 1 1 1 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 AAZ36778.1 - 2.7e-10 40.5 0.0 4.2e-06 27.0 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 AAZ36778.1 - 0.0023 18.1 0.0 1.4 9.0 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_6 PF18029.1 AAZ36778.1 - 0.1 13.4 0.0 0.34 11.7 0.0 1.8 2 0 0 2 2 2 0 Glyoxalase-like domain DUF1043 PF06295.12 AAZ36779.1 - 1.5e-22 79.9 0.1 2.1e-22 79.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1043) Prominin PF05478.11 AAZ36779.1 - 0.0007 17.7 0.0 0.00081 17.5 0.0 1.0 1 0 0 1 1 1 1 Prominin DUF948 PF06103.11 AAZ36779.1 - 0.009 16.2 0.0 0.014 15.7 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) YtxH PF12732.7 AAZ36779.1 - 0.025 15.1 0.1 0.059 13.9 0.1 1.7 1 1 0 1 1 1 0 YtxH-like protein CcmH PF03918.14 AAZ36779.1 - 0.052 12.8 0.4 0.09 12.1 0.3 1.5 1 1 0 1 1 1 0 Cytochrome C biogenesis protein HlyD_2 PF12700.7 AAZ36779.1 - 0.054 12.2 0.0 0.065 12.0 0.0 1.0 1 0 0 1 1 1 0 HlyD family secretion protein DUF3416 PF11896.8 AAZ36779.1 - 0.069 13.4 0.6 0.087 13.1 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3416) LXG PF04740.12 AAZ36779.1 - 0.071 12.8 0.6 0.099 12.3 0.6 1.1 1 0 0 1 1 1 0 LXG domain of WXG superfamily Pex24p PF06398.11 AAZ36779.1 - 0.084 11.8 0.1 0.11 11.5 0.1 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Clusterin PF01093.17 AAZ36779.1 - 0.098 11.7 0.1 0.11 11.5 0.1 1.1 1 0 0 1 1 1 0 Clusterin Amidohydro_1 PF01979.20 AAZ36779.1 - 0.18 11.1 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 Amidohydrolase family EpuA PF11772.8 AAZ36779.1 - 1.2 8.8 3.0 1.8 8.3 3.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta FUSC PF04632.12 AAZ36779.1 - 2.9 6.3 6.4 11 4.3 6.4 1.7 1 1 0 1 1 1 0 Fusaric acid resistance protein family DcrB PF08786.11 AAZ36780.1 - 2.3e-16 60.1 0.0 2.8e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 DcrB MatE PF01554.18 AAZ36782.1 - 2.2e-49 167.2 39.0 1.4e-25 89.8 13.4 2.7 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 AAZ36782.1 - 6.9 6.7 46.1 1.9 8.6 21.3 4.9 2 1 1 3 3 3 0 Polysaccharide biosynthesis C-terminal domain CsrA PF02599.16 AAZ36783.1 - 1.3e-24 85.9 1.0 1.5e-24 85.7 1.0 1.0 1 0 0 1 1 1 1 Global regulator protein family DUF2997 PF11211.8 AAZ36783.1 - 0.029 14.2 0.4 0.043 13.6 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2997) SNF PF00209.18 AAZ36784.1 - 9e-34 117.0 33.9 8.4e-18 64.3 5.5 2.4 3 0 0 3 3 3 2 Sodium:neurotransmitter symporter family 2-Hacid_dh_C PF02826.19 AAZ36785.1 - 1.1e-43 148.6 0.0 1.4e-43 148.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 AAZ36785.1 - 0.0018 18.5 0.0 0.0025 18.0 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh PF00389.30 AAZ36785.1 - 0.048 13.3 0.0 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain PP-binding PF00550.25 AAZ36786.1 - 2e-08 34.5 0.5 2.2e-08 34.3 0.5 1.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ribosomal_L50 PF10501.9 AAZ36786.1 - 0.033 14.3 0.1 0.034 14.3 0.1 1.2 1 0 0 1 1 1 0 Ribosomal subunit 39S Mqo PF06039.15 AAZ36787.1 - 4.4e-235 780.8 0.0 5e-235 780.6 0.0 1.0 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) DAO PF01266.24 AAZ36787.1 - 6.6e-05 22.7 0.0 0.00015 21.5 0.0 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 AAZ36787.1 - 0.00026 20.3 0.0 0.015 14.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_6 PF12697.7 AAZ36788.1 - 8.1e-20 72.4 0.0 1e-19 72.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AAZ36788.1 - 9.6e-19 68.0 0.0 2.8e-17 63.2 0.0 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AAZ36788.1 - 4.8e-16 58.8 0.1 1.4e-15 57.2 0.1 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF1057 PF06342.12 AAZ36788.1 - 2.2e-07 30.2 0.0 3.2e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) DUF915 PF06028.11 AAZ36788.1 - 0.00014 21.3 0.0 0.00021 20.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Chlorophyllase2 PF12740.7 AAZ36788.1 - 0.0002 20.4 0.0 0.00034 19.6 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Ndr PF03096.14 AAZ36788.1 - 0.00089 18.0 0.0 0.0014 17.4 0.0 1.3 1 0 0 1 1 1 1 Ndr family Chlorophyllase PF07224.11 AAZ36788.1 - 0.021 13.9 0.0 0.057 12.4 0.0 1.6 1 1 0 1 1 1 0 Chlorophyllase DUF676 PF05057.14 AAZ36788.1 - 0.021 14.3 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) UPF0227 PF05728.12 AAZ36788.1 - 0.039 13.9 0.0 0.055 13.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF3530 PF12048.8 AAZ36788.1 - 0.077 12.4 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) ECH_1 PF00378.20 AAZ36789.1 - 2.8e-45 154.6 0.2 3.6e-45 154.2 0.2 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AAZ36789.1 - 1.1e-26 94.1 0.2 1.2e-25 90.8 0.1 1.9 1 1 0 2 2 2 1 Enoyl-CoA hydratase/isomerase DUF21 PF01595.20 AAZ36790.1 - 3.4e-49 166.9 0.0 5.2e-49 166.3 0.0 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CorC_HlyC PF03471.17 AAZ36790.1 - 3.9e-17 62.0 0.1 9.1e-17 60.8 0.1 1.7 1 0 0 1 1 1 1 Transporter associated domain CBS PF00571.28 AAZ36790.1 - 8.3e-17 61.4 0.0 3.1e-07 30.7 0.0 2.5 2 0 0 2 2 2 2 CBS domain MFS_1 PF07690.16 AAZ36791.1 - 6.1e-54 183.3 39.2 6.1e-54 183.3 39.2 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 AAZ36791.1 - 9.9e-17 60.9 19.4 7.9e-15 54.7 10.2 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 AAZ36791.1 - 9.9e-08 30.8 17.8 2.4e-07 29.6 17.7 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 AAZ36791.1 - 0.00019 20.4 6.0 0.00019 20.4 6.0 2.7 2 1 0 2 2 2 1 MFS_1 like family OATP PF03137.20 AAZ36791.1 - 0.00047 18.6 1.1 0.0011 17.4 0.4 1.9 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family ATG22 PF11700.8 AAZ36791.1 - 0.00073 18.3 8.1 0.00073 18.3 8.1 2.4 3 0 0 3 3 3 1 Vacuole effluxer Atg22 like ABC_tran PF00005.27 AAZ36792.1 - 1.3e-32 113.2 0.1 1.9e-32 112.6 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAZ36792.1 - 7.3e-10 39.1 2.7 2.2e-05 24.4 0.1 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAZ36792.1 - 9.3e-05 22.0 0.2 0.012 15.0 0.2 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AAZ36792.1 - 0.0003 21.2 0.0 0.00076 19.9 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AAZ36792.1 - 0.00036 20.5 0.2 0.0022 17.9 0.1 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 AAZ36792.1 - 0.00045 19.9 0.2 0.0012 18.6 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 AAZ36792.1 - 0.00068 19.4 0.2 0.0029 17.4 0.1 1.8 2 0 0 2 2 2 1 AAA ATPase domain Dynamin_N PF00350.23 AAZ36792.1 - 0.0091 16.1 0.1 0.028 14.5 0.1 1.7 1 1 0 1 1 1 1 Dynamin family AAA_25 PF13481.6 AAZ36792.1 - 0.01 15.4 0.1 0.068 12.7 0.0 2.2 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 AAZ36792.1 - 0.012 15.7 0.1 0.016 15.3 0.1 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 AAZ36792.1 - 0.037 14.3 0.2 0.24 11.7 0.2 2.0 1 1 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 AAZ36792.1 - 0.046 13.4 0.0 0.066 12.9 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Sigma54_activat PF00158.26 AAZ36792.1 - 0.054 13.2 0.1 6.7 6.4 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_23 PF13476.6 AAZ36792.1 - 0.055 14.0 0.1 0.084 13.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 AAZ36792.1 - 0.085 12.0 0.1 0.24 10.6 0.1 1.8 1 1 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.6 AAZ36792.1 - 0.1 12.8 0.0 0.23 11.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_13 PF13166.6 AAZ36792.1 - 0.11 11.1 0.0 0.3 9.7 0.0 1.5 1 1 0 2 2 2 0 AAA domain BCA_ABC_TP_C PF12399.8 AAZ36792.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Branched-chain amino acid ATP-binding cassette transporter SbcCD_C PF13558.6 AAZ36792.1 - 0.14 12.4 0.1 1 9.6 0.1 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit FCD PF07729.12 AAZ36793.1 - 2.7e-21 76.3 8.2 2.7e-21 76.3 8.2 1.6 2 0 0 2 2 2 1 FCD domain GntR PF00392.21 AAZ36793.1 - 3e-17 62.0 1.8 4.7e-17 61.4 0.2 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_11 PF08279.12 AAZ36793.1 - 0.0007 19.5 0.3 0.0018 18.2 0.0 1.8 2 0 0 2 2 2 1 HTH domain HTH_DeoR PF08220.12 AAZ36793.1 - 0.0035 17.1 0.0 0.0071 16.1 0.0 1.5 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_28 PF13518.6 AAZ36793.1 - 0.0036 17.4 0.8 0.008 16.3 0.1 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 AAZ36793.1 - 0.0098 15.9 0.0 0.025 14.5 0.0 1.7 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Reductase_C PF14759.6 AAZ36793.1 - 0.055 14.0 0.1 0.14 12.7 0.1 1.7 1 0 0 1 1 1 0 Reductase C-terminal PaaX PF07848.12 AAZ36793.1 - 0.092 13.0 0.2 0.22 11.8 0.2 1.6 1 0 0 1 1 1 0 PaaX-like protein CvfB_WH PF17783.1 AAZ36793.1 - 0.14 12.0 0.0 22 4.9 0.0 2.4 2 0 0 2 2 2 0 CvfB-like winged helix domain HMGL-like PF00682.19 AAZ36794.1 - 2e-76 257.0 0.0 3e-76 256.5 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 AAZ36794.1 - 4.8e-28 97.7 0.3 8.9e-28 96.8 0.3 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Response_reg PF00072.24 AAZ36795.1 - 1.1e-20 73.9 0.1 1.2e-20 73.7 0.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain FleQ PF06490.11 AAZ36795.1 - 0.019 15.4 0.2 0.023 15.1 0.2 1.1 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ OKR_DC_1_N PF03709.15 AAZ36795.1 - 0.037 14.3 0.0 0.048 13.9 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain Alginate_lyase PF05426.12 AAZ36796.1 - 4.9e-64 216.5 4.8 6.2e-64 216.2 4.8 1.1 1 0 0 1 1 1 1 Alginate lyase TMEM191C PF15194.6 AAZ36796.1 - 0.076 13.2 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 TMEM191C family NIR_SIR PF01077.22 AAZ36797.1 - 8.2e-58 194.4 0.0 3.7e-42 143.5 0.0 2.3 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 AAZ36797.1 - 4.1e-34 116.2 0.0 6.4e-16 58.0 0.0 2.7 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain SHOCT PF09851.9 AAZ36797.1 - 2.2 8.1 4.8 1.2 8.9 0.7 2.8 3 0 0 3 3 3 0 Short C-terminal domain ThiI PF02568.14 AAZ36798.1 - 1.6e-60 204.1 0.0 2.4e-60 203.5 0.0 1.2 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) THUMP PF02926.17 AAZ36798.1 - 2.1e-15 57.1 0.1 1.9e-14 54.0 0.0 2.4 2 0 0 2 2 2 1 THUMP domain QueC PF06508.13 AAZ36798.1 - 2.6e-05 23.8 0.0 0.0015 18.0 0.0 2.4 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC Rhodanese PF00581.20 AAZ36798.1 - 0.004 17.7 0.0 0.032 14.7 0.0 2.5 2 1 0 2 2 2 1 Rhodanese-like domain tRNA_Me_trans PF03054.16 AAZ36798.1 - 0.024 13.4 0.0 0.063 12.1 0.0 1.7 1 0 0 1 1 1 0 tRNA methyl transferase RHS_repeat PF05593.14 AAZ36799.1 - 1.4e-14 54.2 33.8 0.049 14.2 1.2 11.2 9 2 2 11 11 11 8 RHS Repeat TTc_toxin_rep PF18807.1 AAZ36799.1 - 0.086 12.7 0.1 0.25 11.2 0.1 1.9 1 0 0 1 1 1 0 Tripartite Tc toxins repeat Methyltransf_25 PF13649.6 AAZ36800.1 - 1.5e-14 54.5 0.0 2.9e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAZ36800.1 - 7.3e-14 52.2 0.0 1.4e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAZ36800.1 - 2.6e-08 33.8 0.0 3.8e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAZ36800.1 - 1.8e-07 31.1 0.0 2.7e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAZ36800.1 - 2.3e-07 31.4 0.0 6.5e-07 30.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 AAZ36800.1 - 2.3e-05 23.8 0.0 3.3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 AAZ36800.1 - 0.0052 15.8 0.0 0.0063 15.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MetW PF07021.12 AAZ36800.1 - 0.014 15.0 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW SIR2 PF02146.17 AAZ36801.1 - 8e-35 120.3 0.0 1.1e-34 120.0 0.0 1.1 1 0 0 1 1 1 1 Sir2 family Zn-ribbon_8 PF09723.10 AAZ36801.1 - 0.055 13.6 1.0 0.12 12.5 1.0 1.6 1 0 0 1 1 1 0 Zinc ribbon domain DZR PF12773.7 AAZ36801.1 - 0.074 13.1 0.4 0.19 11.8 0.4 1.6 1 0 0 1 1 1 0 Double zinc ribbon YgbB PF02542.16 AAZ36802.1 - 1.6e-67 226.7 0.5 1.7e-67 226.5 0.5 1.0 1 0 0 1 1 1 1 YgbB family RcpC PF16976.5 AAZ36803.1 - 8.8e-25 87.0 1.0 1.6e-24 86.1 1.0 1.5 1 0 0 1 1 1 1 Flp pilus assembly protein RcpC/CpaB SAF PF08666.12 AAZ36803.1 - 1.3e-13 51.3 0.4 1.6e-09 38.2 0.0 3.3 2 1 1 3 3 3 2 SAF domain ChapFlgA PF13144.6 AAZ36803.1 - 0.0023 18.0 0.0 0.012 15.6 0.0 2.1 3 0 0 3 3 3 1 Chaperone for flagella basal body P-ring formation VOMI PF03762.17 AAZ36804.1 - 6.5e-38 130.5 1.1 1.1e-37 129.7 1.1 1.4 1 0 0 1 1 1 1 Vitelline membrane outer layer protein I (VOMI) DUF169 PF02596.15 AAZ36804.1 - 0.026 14.4 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised ArCR, COG2043 Metallophos PF00149.28 AAZ36804.1 - 0.046 14.2 0.1 0.082 13.4 0.1 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase Abhydrolase_1 PF00561.20 AAZ36805.1 - 2.3e-20 73.3 0.2 1.1e-13 51.5 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AAZ36805.1 - 5.1e-12 45.6 0.1 2.2e-11 43.5 0.1 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Torsin PF06309.11 AAZ36805.1 - 0.098 12.8 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Torsin DUF4892 PF16234.5 AAZ36806.1 - 6.9e-96 319.0 0.2 8.6e-96 318.7 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4892) Hexapep PF00132.24 AAZ36807.1 - 6.6e-10 38.3 8.9 0.0031 17.2 0.1 4.4 4 0 0 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AAZ36807.1 - 0.0011 18.7 3.7 0.073 12.8 0.2 2.9 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase DUF3425 PF11905.8 AAZ36807.1 - 0.13 12.2 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3425) VWA_CoxE PF05762.14 AAZ36808.1 - 2.9e-10 39.9 0.0 2e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein HTH_Tnp_Tc3_1 PF11427.8 AAZ36808.1 - 0.2 11.5 0.1 0.41 10.5 0.1 1.5 1 0 0 1 1 1 0 Tc3 transposase Ribonuc_L-PSP PF01042.21 AAZ36809.1 - 3.9e-29 101.1 0.0 4.4e-29 100.9 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP HTH_26 PF13443.6 AAZ36809.1 - 0.21 12.1 0.2 0.36 11.3 0.2 1.3 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Acetyltransf_10 PF13673.7 AAZ36812.1 - 3.6e-17 62.5 0.0 4.2e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAZ36812.1 - 9.8e-12 45.1 0.0 1.4e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAZ36812.1 - 3.9e-10 40.0 0.0 5.4e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 AAZ36812.1 - 4.4e-06 26.6 0.0 6.9e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 AAZ36812.1 - 2.6e-05 24.4 0.0 4.1e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AAZ36812.1 - 0.034 14.2 0.0 0.092 12.8 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DAO PF01266.24 AAZ36813.1 - 1.2e-48 166.5 0.2 1.8e-48 165.9 0.0 1.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO_C PF16901.5 AAZ36813.1 - 2.4e-13 50.1 0.0 4.7e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 AAZ36813.1 - 0.0061 15.7 0.6 0.047 12.8 0.7 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 AAZ36813.1 - 0.018 14.3 0.1 0.068 12.4 0.1 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AAZ36813.1 - 0.02 14.3 0.9 0.19 11.1 1.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 AAZ36813.1 - 0.051 13.5 0.0 0.085 12.7 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 AAZ36813.1 - 0.18 12.3 0.1 0.85 10.2 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AAZ36813.1 - 0.26 9.9 0.2 0.44 9.2 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein rve PF00665.26 AAZ36814.1 - 7.5e-14 52.0 0.0 1.7e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain HTH_23 PF13384.6 AAZ36814.1 - 8.3e-05 22.3 0.0 0.00023 20.8 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain DUF1804 PF08822.11 AAZ36814.1 - 0.00057 19.9 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1804) HTH_3 PF01381.22 AAZ36814.1 - 0.001 19.1 0.0 0.0029 17.6 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix Sigma70_r4 PF04545.16 AAZ36814.1 - 0.0029 17.1 0.1 0.0085 15.6 0.1 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_29 PF13551.6 AAZ36814.1 - 0.0092 16.0 0.0 0.027 14.5 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_36 PF13730.6 AAZ36814.1 - 0.0098 15.8 0.1 0.022 14.7 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_40 PF14493.6 AAZ36814.1 - 0.025 15.0 0.0 0.073 13.5 0.0 1.9 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_17 PF12728.7 AAZ36814.1 - 0.035 14.3 0.0 0.09 13.0 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_38 PF13936.6 AAZ36814.1 - 0.037 13.8 0.9 0.082 12.7 0.2 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain DUF746 PF05344.11 AAZ36814.1 - 0.043 13.6 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) HTH_Tnp_1 PF01527.20 AAZ36814.1 - 0.045 14.1 0.0 0.13 12.5 0.0 1.8 1 0 0 1 1 1 0 Transposase HTH_30 PF13556.6 AAZ36814.1 - 0.063 13.1 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_28 PF13518.6 AAZ36814.1 - 0.069 13.3 0.1 0.18 11.9 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_11 PF08279.12 AAZ36814.1 - 0.12 12.3 0.1 0.25 11.3 0.1 1.5 1 0 0 1 1 1 0 HTH domain MerR PF00376.23 AAZ36814.1 - 0.16 11.8 0.0 0.45 10.3 0.0 1.7 1 0 0 1 1 1 0 MerR family regulatory protein Sigma70_r4_2 PF08281.12 AAZ36814.1 - 0.17 11.6 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Cytochrome_CBB3 PF13442.6 AAZ36816.1 - 5.9e-10 39.3 0.3 7.7e-10 39.0 0.3 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AAZ36816.1 - 0.055 14.6 0.6 0.081 14.1 0.6 1.5 1 1 0 1 1 1 0 Cytochrome c HTH_3 PF01381.22 AAZ36817.1 - 9e-08 32.1 0.0 1.3e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 AAZ36817.1 - 9.8e-08 32.2 0.1 1.3e-07 31.9 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain Pou PF00157.17 AAZ36817.1 - 0.00091 19.2 0.1 0.0016 18.4 0.1 1.6 1 1 0 1 1 1 1 Pou domain - N-terminal to homeobox domain HTH_19 PF12844.7 AAZ36817.1 - 0.0089 16.0 0.2 0.018 15.0 0.2 1.5 1 1 0 1 1 1 1 Helix-turn-helix domain LigA PF07746.11 AAZ36817.1 - 0.13 12.5 0.0 0.15 12.3 0.0 1.1 1 0 0 1 1 1 0 Aromatic-ring-opening dioxygenase LigAB, LigA subunit ABC_tran PF00005.27 AAZ36818.1 - 6.7e-31 107.6 0.0 1.1e-30 107.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 AAZ36818.1 - 3.4e-28 99.1 7.5 5.8e-28 98.3 7.5 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 AAZ36818.1 - 1.2e-05 24.8 0.0 0.002 17.6 0.0 2.2 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 AAZ36818.1 - 0.0015 18.2 0.0 0.0035 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 AAZ36818.1 - 0.002 18.0 0.1 0.039 13.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 AAZ36818.1 - 0.0037 17.2 0.0 0.0074 16.2 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA PF00004.29 AAZ36818.1 - 0.0044 17.4 0.0 0.027 14.9 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AAZ36818.1 - 0.0067 16.8 0.4 0.023 15.1 0.3 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AAZ36818.1 - 0.0081 15.9 0.1 0.021 14.6 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AAZ36818.1 - 0.015 15.5 0.1 0.057 13.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 AAZ36818.1 - 0.025 14.3 0.0 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 AAZ36818.1 - 0.028 14.1 0.0 0.062 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 AAZ36818.1 - 0.029 13.2 0.0 1.3 7.8 0.0 2.6 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_18 PF13238.6 AAZ36818.1 - 0.043 14.4 0.0 0.23 12.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 AAZ36818.1 - 0.047 13.6 0.5 0.28 11.1 0.1 2.4 3 0 0 3 3 3 0 NACHT domain AAA_33 PF13671.6 AAZ36818.1 - 0.048 13.8 0.1 0.12 12.5 0.1 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 AAZ36818.1 - 0.12 12.3 0.0 0.33 10.8 0.0 1.7 2 0 0 2 2 2 0 NTPase Cytidylate_kin PF02224.18 AAZ36818.1 - 0.13 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase AAA_23 PF13476.6 AAZ36818.1 - 0.2 12.1 0.0 0.3 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 AAZ36819.1 - 1.1e-72 244.2 0.2 1.5e-72 243.7 0.2 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 AAZ36819.1 - 2.2e-44 150.8 1.1 3.6e-44 150.1 1.1 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 AAZ36819.1 - 2.9e-15 56.5 0.9 7e-15 55.3 0.9 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 AAZ36819.1 - 3.3e-08 33.6 1.0 7.2e-08 32.5 0.4 2.0 2 0 0 2 2 2 1 HAS barrel domain ATPase_2 PF01637.18 AAZ36819.1 - 0.095 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Nup54 PF13874.6 AAZ36819.1 - 0.15 12.2 0.1 0.28 11.3 0.1 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Alpha-amylase PF00128.24 AAZ36820.1 - 0.0021 17.7 0.0 0.012 15.2 0.0 1.9 1 1 0 1 1 1 1 Alpha amylase, catalytic domain OSCP PF00213.18 AAZ36821.1 - 2.1e-54 184.2 1.2 2.3e-54 184.1 1.2 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Phage_integrase PF00589.22 AAZ36822.1 - 1.4e-10 41.2 0.1 4e-10 39.7 0.1 1.7 2 0 0 2 2 2 1 Phage integrase family Phage_int_SAM_1 PF02899.17 AAZ36822.1 - 1.4e-06 28.5 0.1 3.8e-06 27.1 0.1 1.7 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Arm-DNA-bind_1 PF09003.10 AAZ36822.1 - 0.0002 21.5 0.1 0.00038 20.5 0.1 1.4 1 0 0 1 1 1 1 Bacteriophage lambda integrase, Arm DNA-binding domain Phage_int_SAM_5 PF13102.6 AAZ36822.1 - 0.0092 16.3 0.1 3.6 8.0 0.0 2.4 2 0 0 2 2 2 2 Phage integrase SAM-like domain Phage_int_SAM_3 PF14659.6 AAZ36822.1 - 0.054 13.8 0.0 0.088 13.1 0.0 1.4 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain DUF454 PF04304.13 AAZ36824.1 - 3.7e-33 114.0 7.0 4.4e-33 113.7 7.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF454) DUF687 PF05095.12 AAZ36824.1 - 0.004 15.7 0.1 0.0047 15.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF687) Glycos_transf_1 PF00534.20 AAZ36825.1 - 1.3e-30 106.1 0.0 2e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAZ36825.1 - 3.9e-21 75.9 0.0 9.1e-21 74.7 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAZ36825.1 - 9.4e-17 61.5 0.0 1.7e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AAZ36825.1 - 8.6e-14 52.3 0.1 2.6e-13 50.7 0.0 1.9 3 0 0 3 3 3 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 AAZ36825.1 - 0.00081 19.7 0.0 0.0017 18.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 SGL PF08450.12 AAZ36826.1 - 3.1e-71 239.8 0.0 3.6e-71 239.6 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Carboxyl_trans PF01039.22 AAZ36827.1 - 7.8e-16 57.8 0.1 8.8e-16 57.6 0.1 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain BPD_transp_1 PF00528.22 AAZ36828.1 - 1.1e-19 70.9 19.9 1.1e-19 70.9 19.9 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component Fic PF02661.18 AAZ36829.1 - 7.4e-17 62.0 0.0 4.1e-16 59.7 0.0 2.1 2 0 0 2 2 2 1 Fic/DOC family MarR_2 PF12802.7 AAZ36829.1 - 0.04 13.8 0.2 0.04 13.8 0.2 2.2 3 0 0 3 3 3 0 MarR family HATPase_c PF02518.26 AAZ36830.1 - 1.6e-27 96.2 0.0 4.2e-27 94.9 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AAZ36830.1 - 2.7e-27 95.2 0.0 1e-26 93.3 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 AAZ36830.1 - 1.9e-16 59.9 2.9 2e-16 59.8 0.4 2.5 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AAZ36830.1 - 0.016 15.5 0.0 0.058 13.8 0.0 2.0 1 0 0 1 1 1 0 HAMP domain HATPase_c_3 PF13589.6 AAZ36830.1 - 0.037 13.9 0.0 0.072 12.9 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IFT57 PF10498.9 AAZ36830.1 - 0.037 13.0 0.3 0.1 11.6 0.4 1.6 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Jnk-SapK_ap_N PF09744.9 AAZ36830.1 - 0.064 13.5 1.7 0.13 12.5 1.7 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF4164 PF13747.6 AAZ36830.1 - 0.069 13.4 6.0 0.082 13.2 3.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) DUF4166 PF13761.6 AAZ36830.1 - 0.07 12.9 0.1 0.98 9.2 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4166) DUF2848 PF11010.8 AAZ36830.1 - 0.074 12.7 0.0 1.3 8.6 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2848) NAD_Gly3P_dh_N PF01210.23 AAZ36831.1 - 7.1e-50 169.0 0.1 1.5e-49 167.9 0.1 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 AAZ36831.1 - 1.6e-45 154.9 2.5 2.1e-45 154.5 0.8 1.9 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 AAZ36831.1 - 1.5e-10 41.5 0.0 7.5e-10 39.3 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 AAZ36831.1 - 5.8e-08 32.5 0.0 9.9e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 AAZ36831.1 - 5.6e-05 23.3 0.0 0.00051 20.2 0.0 2.2 1 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 AAZ36831.1 - 0.00025 21.0 0.0 0.00057 19.8 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 AAZ36831.1 - 0.00027 21.2 0.3 0.0034 17.6 0.0 2.5 2 1 0 2 2 2 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 AAZ36831.1 - 0.00061 20.0 0.0 0.046 14.0 0.0 2.6 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 AAZ36831.1 - 0.0027 17.6 0.1 0.008 16.1 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding Shikimate_DH PF01488.20 AAZ36831.1 - 0.039 14.0 0.0 0.11 12.5 0.0 1.8 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 AAZ36831.1 - 0.082 12.3 0.0 0.27 10.6 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 AAZ36831.1 - 0.1 12.2 0.0 0.36 10.4 0.0 2.0 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain SPA PF08616.10 AAZ36831.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 Stabilization of polarity axis DUF2634 PF10934.8 AAZ36831.1 - 0.19 11.9 0.0 0.6 10.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2634) Pribosyltran PF00156.27 AAZ36832.1 - 2.2e-12 46.8 0.0 3.4e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 AAZ36832.1 - 0.021 14.4 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase PA PF02225.22 AAZ36832.1 - 0.024 14.6 0.1 0.039 14.0 0.1 1.3 1 0 0 1 1 1 0 PA domain MCPsignal PF00015.21 AAZ36833.1 - 2.3e-24 86.1 14.7 2.3e-24 86.1 14.7 2.6 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Sec20 PF03908.13 AAZ36833.1 - 0.039 13.9 7.2 2.1 8.3 0.9 3.1 2 1 0 2 2 2 0 Sec20 ApoLp-III PF07464.11 AAZ36833.1 - 0.58 10.2 15.4 0.13 12.3 4.0 3.5 2 2 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) CheZ PF04344.13 AAZ36833.1 - 1.1 9.1 18.4 0.076 12.9 4.8 3.1 1 1 0 3 3 3 0 Chemotaxis phosphatase, CheZ DOG1 PF14144.6 AAZ36833.1 - 1.5 9.1 7.2 1.3 9.3 0.2 3.5 4 0 0 4 4 4 0 Seed dormancy control TMF_TATA_bd PF12325.8 AAZ36833.1 - 2 8.6 9.7 0.93 9.7 0.2 3.6 3 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding DUF4381 PF14316.6 AAZ36833.1 - 2.2 8.5 10.5 0.078 13.2 0.8 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) Snapin_Pallidin PF14712.6 AAZ36833.1 - 2.4 8.6 7.0 3.2 8.2 0.3 3.5 3 1 0 3 3 3 0 Snapin/Pallidin Prominin PF05478.11 AAZ36833.1 - 8.3 4.2 9.1 1.4 6.8 0.9 2.0 1 1 1 2 2 2 0 Prominin DUF179 PF02622.15 AAZ36834.1 - 6.8e-44 149.7 0.0 7.7e-44 149.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 HATPase_c PF02518.26 AAZ36835.1 - 1.8e-16 60.6 0.0 2.8e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAZ36835.1 - 9.5e-12 44.8 0.5 2e-11 43.7 0.5 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AAZ36835.1 - 1.3e-08 35.0 1.1 1.3e-08 35.0 1.1 2.0 2 0 0 2 2 2 1 HAMP domain STAT2_C PF12188.8 AAZ36835.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Signal transducer and activator of transcription 2 C terminal AAA_11 PF13086.6 AAZ36836.1 - 1.8e-19 70.5 0.0 2.7e-18 66.7 0.1 2.4 2 1 0 2 2 2 1 AAA domain AAA_12 PF13087.6 AAZ36836.1 - 6.8e-19 68.3 0.0 6.6e-18 65.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain DUF2726 PF10881.8 AAZ36836.1 - 1.3e-13 51.0 0.1 5e-13 49.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2726) AAA_30 PF13604.6 AAZ36836.1 - 3.1e-12 46.6 0.2 4e-08 33.2 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 AAZ36836.1 - 3.9e-10 40.2 0.1 6.1e-09 36.4 0.1 2.4 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 AAZ36836.1 - 2.5e-09 37.2 0.2 0.0093 15.7 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 AAZ36836.1 - 5.6e-06 25.8 0.0 1.5e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 AAZ36836.1 - 6.3e-05 22.7 0.6 0.00061 19.4 0.6 2.2 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain DUF559 PF04480.12 AAZ36836.1 - 0.00025 20.9 0.0 0.00058 19.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF559) UvrD_C_2 PF13538.6 AAZ36836.1 - 0.0004 20.1 0.0 0.00086 19.1 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain ResIII PF04851.15 AAZ36836.1 - 0.0056 16.7 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DnaB_C PF03796.15 AAZ36836.1 - 0.0056 16.0 0.1 0.14 11.5 0.0 2.2 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain MTES_1575 PF18741.1 AAZ36836.1 - 0.0064 16.7 0.0 0.016 15.4 0.0 1.7 1 0 0 1 1 1 1 REase_MTES_1575 cobW PF02492.19 AAZ36836.1 - 0.013 15.1 0.2 0.027 14.1 0.2 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Helicase_RecD PF05127.14 AAZ36836.1 - 0.019 14.9 0.0 0.1 12.5 0.0 2.1 2 0 0 2 2 2 0 Helicase AAA_28 PF13521.6 AAZ36836.1 - 0.06 13.6 0.2 12 6.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 AAZ36836.1 - 0.064 12.8 0.0 0.35 10.4 0.0 2.2 3 0 0 3 3 3 0 AAA domain TrwB_AAD_bind PF10412.9 AAZ36836.1 - 0.082 11.8 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA PF00004.29 AAZ36836.1 - 0.16 12.4 0.0 0.39 11.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 AAZ36836.1 - 0.16 11.4 0.2 0.45 9.9 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein Adeno_IVa2 PF02456.15 AAZ36836.1 - 0.17 10.7 0.0 0.29 9.9 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein HEM4 PF02602.15 AAZ36837.1 - 2.3e-33 115.5 0.0 2.6e-33 115.3 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD BPD_transp_2 PF02653.16 AAZ36838.1 - 6.4e-28 97.7 43.0 6.4e-28 97.7 43.0 1.9 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component DUF883 PF05957.13 AAZ36838.1 - 0.15 12.7 0.5 0.45 11.2 0.5 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Oxidored_FMN PF00724.20 AAZ36839.1 - 4.3e-66 223.5 0.0 5.8e-66 223.1 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.14 AAZ36839.1 - 7.8e-12 45.0 1.2 4.3e-11 42.6 1.2 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AAZ36839.1 - 7.5e-10 38.9 0.0 1.3e-08 35.0 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 AAZ36839.1 - 2.2e-08 33.9 0.3 3.6e-08 33.2 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 AAZ36839.1 - 1e-07 32.4 0.1 4.5e-05 23.9 0.1 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AAZ36839.1 - 5.8e-07 28.6 0.2 9.3e-07 27.9 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 AAZ36839.1 - 1.2e-06 27.9 0.8 2.6e-06 26.8 0.4 1.7 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 AAZ36839.1 - 1.8e-05 24.0 0.2 2.9e-05 23.3 0.2 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 AAZ36839.1 - 0.00011 21.5 0.1 0.00099 18.4 0.1 2.1 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 AAZ36839.1 - 0.0003 20.5 0.1 0.00069 19.3 0.1 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 AAZ36839.1 - 0.00056 19.3 0.1 0.001 18.4 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 AAZ36839.1 - 0.00064 19.1 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 AAZ36839.1 - 0.0058 15.9 0.0 0.013 14.8 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 AAZ36839.1 - 0.01 15.7 0.1 0.022 14.7 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Amino_oxidase PF01593.24 AAZ36839.1 - 0.012 15.0 0.0 0.038 13.3 0.0 1.8 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.6 AAZ36839.1 - 0.068 13.6 0.1 0.17 12.3 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding FMO-like PF00743.19 AAZ36839.1 - 0.11 10.9 0.0 0.19 10.1 0.0 1.3 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like HTH_1 PF00126.27 AAZ36840.1 - 9.9e-17 60.7 0.6 2.3e-16 59.5 0.6 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 AAZ36840.1 - 4.5e-16 58.9 1.3 7.5e-16 58.1 1.3 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_38 PF13936.6 AAZ36840.1 - 0.02 14.6 0.2 0.039 13.7 0.2 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_28 PF13518.6 AAZ36840.1 - 0.051 13.7 0.3 0.69 10.1 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain Response_reg PF00072.24 AAZ36841.1 - 2.2e-44 150.2 0.4 3.8e-22 78.6 0.0 2.7 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 AAZ36841.1 - 1.2e-18 66.8 0.1 5.1e-18 64.9 0.1 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain 7TMR-DISMED2 PF07696.11 AAZ36841.1 - 6.4e-18 65.1 0.1 3e-17 62.9 0.2 2.0 2 0 0 2 2 2 1 7TMR-DISM extracellular 2 7TMR-DISM_7TM PF07695.11 AAZ36841.1 - 1.1e-17 64.6 20.8 1.7e-17 64.0 20.8 1.2 1 0 0 1 1 1 1 7TM diverse intracellular signalling HATPase_c PF02518.26 AAZ36841.1 - 1.9e-13 50.9 0.0 3.8e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1129 PF06570.11 AAZ36841.1 - 6.1 6.3 6.5 1.3 8.5 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) SBP_bac_3 PF00497.20 AAZ36842.1 - 1.3e-58 198.1 0.1 1.5e-58 197.9 0.1 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1 PF09084.11 AAZ36842.1 - 1.4e-07 31.7 0.1 1.9e-07 31.2 0.1 1.4 1 0 0 1 1 1 1 NMT1/THI5 like Lig_chan-Glu_bd PF10613.9 AAZ36842.1 - 4.9e-07 29.9 0.0 2e-06 28.0 0.0 2.0 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site TerB PF05099.13 AAZ36843.1 - 1.3e-27 96.5 0.2 1.4e-27 96.4 0.2 1.0 1 0 0 1 1 1 1 Tellurite resistance protein TerB DUF533 PF04391.12 AAZ36843.1 - 3e-05 23.7 0.1 0.19 11.3 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF533) CheB_methylest PF01339.17 AAZ36844.1 - 4.9e-59 198.9 1.6 8.2e-59 198.1 0.4 1.9 2 0 0 2 2 2 1 CheB methylesterase Response_reg PF00072.24 AAZ36844.1 - 9.3e-23 80.5 0.1 2.4e-22 79.2 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain TAL_effector PF03377.13 AAZ36844.1 - 0.089 13.1 1.0 0.39 11.1 0.1 2.4 2 0 0 2 2 2 0 TAL effector repeat Virul_fac_BrkB PF03631.15 AAZ36846.1 - 1.7e-67 227.8 27.7 1.9e-67 227.6 27.7 1.0 1 0 0 1 1 1 1 Virulence factor BrkB DUF4577 PF15145.6 AAZ36846.1 - 3 7.9 4.5 8.4 6.4 0.0 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4577) DUF3671 PF12420.8 AAZ36846.1 - 5.2 7.2 7.3 6 7.0 3.9 2.3 2 1 0 2 2 2 0 Protein of unknown function Phosphorylase PF00343.20 AAZ36847.1 - 1.9e-301 1001.6 0.0 2.2e-301 1001.4 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase AP_endonuc_2 PF01261.24 AAZ36848.1 - 2.2e-38 131.8 0.1 3.8e-38 131.0 0.1 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Glyoxalase_5 PF14696.6 AAZ36848.1 - 1.5e-30 106.2 0.0 2.8e-30 105.3 0.0 1.5 1 0 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase PF00903.25 AAZ36848.1 - 5.4e-11 42.8 0.0 3.1e-10 40.3 0.0 2.1 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 AAZ36848.1 - 6.2e-08 32.9 0.0 0.00026 21.3 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 AAZ36848.1 - 0.031 15.1 0.0 0.29 11.9 0.0 2.4 2 0 0 2 2 2 0 Glyoxalase-like domain Glyoxalase_3 PF13468.6 AAZ36848.1 - 0.084 13.0 0.0 0.43 10.7 0.0 2.0 2 0 0 2 2 2 0 Glyoxalase-like domain DUF3613 PF12266.8 AAZ36849.1 - 2.5e-19 68.8 7.3 3e-19 68.6 7.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3613) HTH_5 PF01022.20 AAZ36850.1 - 3.7e-10 39.5 0.0 7e-09 35.4 0.0 2.4 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 AAZ36850.1 - 1.2e-09 38.1 3.6 1.3e-09 38.0 1.7 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.7 AAZ36850.1 - 0.0015 18.4 0.8 0.0015 18.4 0.8 2.5 3 0 0 3 3 3 1 MarR family HTH_27 PF13463.6 AAZ36850.1 - 0.0018 18.8 0.4 0.41 11.2 0.1 3.2 3 0 0 3 3 3 1 Winged helix DNA-binding domain TrmB PF01978.19 AAZ36850.1 - 0.0026 17.6 0.0 0.011 15.6 0.0 2.1 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_45 PF14947.6 AAZ36850.1 - 0.024 14.6 0.0 3.7 7.6 0.0 2.9 3 0 0 3 3 3 0 Winged helix-turn-helix HTH_13 PF11972.8 AAZ36850.1 - 0.042 13.9 0.1 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 HTH DNA binding domain HTH_IclR PF09339.10 AAZ36850.1 - 0.051 13.4 0.4 0.051 13.4 0.4 2.2 3 0 0 3 3 3 0 IclR helix-turn-helix domain Rrf2 PF02082.20 AAZ36850.1 - 0.059 13.7 0.3 0.54 10.6 0.1 2.4 1 1 1 2 2 2 0 Transcriptional regulator PaaX PF07848.12 AAZ36850.1 - 0.48 10.7 5.3 0.62 10.3 0.3 3.1 3 1 1 4 4 4 0 PaaX-like protein ADH_zinc_N PF00107.26 AAZ36851.1 - 1.5e-29 102.6 0.6 2.6e-29 101.8 0.6 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AAZ36851.1 - 7.9e-20 72.3 0.0 1.8e-19 71.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AAZ36851.1 - 5.1e-06 26.3 0.2 1.2e-05 25.1 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 AAZ36851.1 - 0.0057 16.0 0.6 0.01 15.1 0.1 1.5 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.21 AAZ36851.1 - 0.0077 16.0 0.2 0.012 15.3 0.2 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TrkA_N PF02254.18 AAZ36851.1 - 0.056 13.7 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Acetyltransf_3 PF13302.7 AAZ36852.1 - 7.5e-24 85.0 0.0 8.9e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAZ36852.1 - 6.9e-09 36.0 0.0 8.5e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 AAZ36852.1 - 3e-07 30.7 0.0 3.2e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAZ36852.1 - 0.00049 20.0 0.0 0.00087 19.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein DUF1345 PF07077.11 AAZ36853.1 - 1.4e-57 194.1 4.8 1.4e-57 194.1 4.8 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF1345) HlyD_3 PF13437.6 AAZ36854.1 - 5.3e-17 62.5 0.9 1.2e-13 51.7 0.1 2.9 2 1 1 3 3 3 2 HlyD family secretion protein HlyD_D23 PF16576.5 AAZ36854.1 - 2.9e-15 56.1 3.3 3.3e-13 49.4 3.3 2.7 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD PF00529.20 AAZ36854.1 - 3.7e-14 52.3 0.1 1.6e-13 50.4 0.1 2.1 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl_2 PF13533.6 AAZ36854.1 - 1.2e-07 31.5 5.3 2.9e-07 30.2 0.2 3.1 3 0 0 3 3 3 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AAZ36854.1 - 0.00045 20.0 0.3 0.069 13.0 0.2 2.6 2 0 0 2 2 2 1 Biotin-requiring enzyme OEP PF02321.18 AAZ36854.1 - 0.00061 19.7 12.4 0.0026 17.6 8.4 2.5 1 1 1 2 2 2 1 Outer membrane efflux protein HMMR_N PF15905.5 AAZ36854.1 - 0.0015 18.1 0.2 0.0021 17.6 0.2 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal Csm1_N PF18504.1 AAZ36854.1 - 0.0038 17.5 3.4 0.023 15.1 0.0 3.1 3 0 0 3 3 3 1 Csm1 N-terminal domain Spc7 PF08317.11 AAZ36854.1 - 0.018 13.9 0.6 0.029 13.2 0.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Syntaxin-6_N PF09177.11 AAZ36854.1 - 0.027 15.0 2.1 0.22 12.1 2.0 2.3 2 1 0 2 2 2 0 Syntaxin 6, N-terminal ApoLp-III PF07464.11 AAZ36854.1 - 0.028 14.5 0.3 0.028 14.5 0.3 1.8 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF3262 PF11660.8 AAZ36854.1 - 0.044 14.2 0.1 0.095 13.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3262) CoatB PF10389.9 AAZ36854.1 - 0.05 13.4 2.6 0.18 11.6 2.6 2.0 1 0 0 1 1 1 0 Bacteriophage coat protein B TPR_MLP1_2 PF07926.12 AAZ36854.1 - 0.091 12.8 4.3 0.17 11.9 4.3 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein LPP PF04728.13 AAZ36854.1 - 0.13 12.7 4.8 0.73 10.3 0.1 2.6 2 0 0 2 2 2 0 Lipoprotein leucine-zipper COG2 PF06148.11 AAZ36854.1 - 0.67 10.0 3.1 12 6.0 0.4 2.3 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ABC_tran PF00005.27 AAZ36855.1 - 3.2e-26 92.5 0.0 7.5e-26 91.3 0.0 1.6 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAZ36855.1 - 1.5e-06 28.3 0.1 0.00092 19.1 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 AAZ36855.1 - 1.6e-05 25.2 0.0 6e-05 23.3 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 AAZ36855.1 - 0.00033 20.9 1.2 0.011 16.0 1.2 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAZ36855.1 - 0.00056 20.3 1.0 0.00098 19.5 1.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 AAZ36855.1 - 0.0018 18.5 0.1 0.0054 16.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AAZ36855.1 - 0.0033 17.3 0.0 0.0054 16.6 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 AAZ36855.1 - 0.0035 17.0 0.1 0.0065 16.2 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.12 AAZ36855.1 - 0.0039 17.1 0.1 0.017 15.0 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.6 AAZ36855.1 - 0.0082 15.7 0.6 0.018 14.6 0.0 1.8 2 1 1 3 3 2 1 AAA domain SMC_N PF02463.19 AAZ36855.1 - 0.017 14.5 0.0 3.6 7.0 0.0 2.1 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 AAZ36855.1 - 0.031 14.5 0.2 0.35 11.1 0.2 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 AAZ36855.1 - 0.045 13.5 0.1 0.16 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 AAZ36855.1 - 0.048 13.0 0.0 0.081 12.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_18 PF13238.6 AAZ36855.1 - 0.085 13.4 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 AAZ36855.1 - 0.12 12.4 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase cobW PF02492.19 AAZ36855.1 - 0.13 11.8 0.1 0.27 10.8 0.0 1.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 AAZ36855.1 - 0.15 12.0 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_ATPase PF09818.9 AAZ36855.1 - 0.18 10.6 0.0 8.4 5.1 0.0 2.3 2 1 0 2 2 2 0 Predicted ATPase of the ABC class AAA_24 PF13479.6 AAZ36855.1 - 0.19 11.4 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 AAZ36855.1 - 0.2 10.8 0.0 0.34 10.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DLIC PF05783.11 AAZ36855.1 - 0.21 10.4 0.0 0.31 9.8 0.0 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) PduV-EutP PF10662.9 AAZ36855.1 - 0.25 11.1 0.0 0.45 10.2 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 AAZ36855.1 - 0.26 10.4 0.0 0.39 9.8 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit SDF PF00375.18 AAZ36856.1 - 7.9e-105 351.1 36.0 8.9e-105 350.9 36.0 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF4658 PF15555.6 AAZ36856.1 - 1.2 9.2 7.7 1.3 9.1 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4658) BPD_transp_1 PF00528.22 AAZ36858.1 - 4.3e-25 88.5 11.6 4.3e-25 88.5 11.6 2.7 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component SspB PF04386.13 AAZ36859.1 - 6.1e-38 130.2 0.0 1.2e-37 129.3 0.0 1.4 1 1 0 1 1 1 1 Stringent starvation protein B Ribosomal_S2 PF00318.20 AAZ36860.1 - 1.4e-94 315.3 0.0 1.6e-94 315.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S2 Dicistro_VP4 PF11492.8 AAZ36860.1 - 0.12 12.4 0.1 0.49 10.4 0.0 2.0 2 0 0 2 2 2 0 Cricket paralysis virus, VP4 SLT PF01464.20 AAZ36861.1 - 1.4e-12 47.3 0.0 2.4e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Transglycosylase SLT domain SBP_bac_3 PF00497.20 AAZ36861.1 - 2.4e-09 37.0 0.1 5.5e-09 35.8 0.0 1.6 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 GST_N_3 PF13417.6 AAZ36862.1 - 6.4e-19 68.1 0.2 1.2e-18 67.2 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AAZ36862.1 - 3.5e-14 52.9 0.0 8e-14 51.7 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 AAZ36862.1 - 5e-13 49.2 0.0 8.1e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 AAZ36862.1 - 1e-08 35.3 0.0 1.6e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 AAZ36862.1 - 5.5e-06 26.3 0.3 2.3e-05 24.3 0.0 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 AAZ36862.1 - 0.15 11.9 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Cupin_2 PF07883.11 AAZ36863.1 - 0.0002 21.0 0.0 0.00039 20.1 0.0 1.5 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 AAZ36863.1 - 0.0096 15.8 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 AAZ36863.1 - 0.16 11.7 0.0 0.68 9.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Exonuc_VII_S PF02609.16 AAZ36864.1 - 8.2e-20 70.6 1.7 1.2e-19 70.1 1.7 1.3 1 0 0 1 1 1 1 Exonuclease VII small subunit FH2 PF02181.23 AAZ36864.1 - 0.029 13.5 0.3 0.036 13.2 0.3 1.0 1 0 0 1 1 1 0 Formin Homology 2 Domain V-SNARE PF05008.15 AAZ36864.1 - 0.13 12.7 1.0 2.2 8.7 0.1 2.1 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DEAD PF00270.29 AAZ36865.1 - 2e-48 164.5 0.1 3e-48 163.9 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AAZ36865.1 - 1.2e-30 106.1 0.0 1.7e-28 99.1 0.0 2.4 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 AAZ36865.1 - 1.6e-08 34.7 0.0 2.9e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 AAZ36865.1 - 0.0012 17.7 0.0 0.18 10.5 0.0 3.1 1 1 2 3 3 3 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DNA_gyraseB PF00204.25 AAZ36866.1 - 7.4e-39 133.0 0.0 1.3e-38 132.2 0.0 1.3 1 0 0 1 1 1 1 DNA gyrase B DNA_gyraseB_C PF00986.21 AAZ36866.1 - 2.8e-24 85.1 0.6 5.4e-24 84.1 0.6 1.5 1 0 0 1 1 1 1 DNA gyrase B subunit, carboxyl terminus HATPase_c PF02518.26 AAZ36866.1 - 1.2e-16 61.2 0.1 2e-16 60.5 0.1 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 AAZ36866.1 - 5.8e-12 45.7 0.0 1.1e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Toprim domain HATPase_c_3 PF13589.6 AAZ36866.1 - 0.0012 18.7 0.0 0.0024 17.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TOPRIM_C PF16898.5 AAZ36866.1 - 0.064 13.5 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 C-terminal associated domain of TOPRIM MFS_1 PF07690.16 AAZ36867.1 - 1.7e-43 148.9 57.4 1.7e-43 148.9 57.4 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 AAZ36867.1 - 8.2e-11 41.0 23.8 1.3e-10 40.3 23.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 AAZ36867.1 - 2.7e-09 36.4 8.8 2.7e-09 36.4 8.8 3.3 2 1 0 3 3 3 1 Sugar (and other) transporter adh_short_C2 PF13561.6 AAZ36868.1 - 3.2e-67 226.5 3.1 3.7e-67 226.3 3.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAZ36868.1 - 4.6e-54 182.8 1.7 5.6e-54 182.6 1.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAZ36868.1 - 3.9e-15 56.2 2.0 7.3e-15 55.3 2.0 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 AAZ36868.1 - 0.022 14.2 1.2 0.033 13.7 0.2 1.9 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family Oxidored_molyb PF00174.19 AAZ36869.1 - 1.1e-32 113.0 0.0 2.4e-32 111.9 0.0 1.5 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain YDG PF18657.1 AAZ36870.1 - 1.5e-92 304.0 110.4 9.8e-16 57.7 6.7 10.1 9 0 0 9 9 9 7 YDG domain Haemagg_act PF05860.13 AAZ36870.1 - 2.9e-21 75.6 1.1 1.9e-20 72.9 1.1 2.5 1 0 0 1 1 1 1 haemagglutination activity domain Adhesin_P1 PF03257.13 AAZ36870.1 - 6.6e-07 29.8 7.5 18 6.0 0.1 6.9 1 1 5 6 6 6 4 Mycoplasma adhesin P1 DUF4024 PF13216.6 AAZ36870.1 - 0.0018 18.1 0.8 2.1e+02 2.0 0.0 5.5 6 0 0 6 6 6 0 Protein of unknown function (DUF4024) DUF1138 PF06592.13 AAZ36870.1 - 0.0045 17.0 26.3 15 5.7 0.3 6.8 6 0 0 6 6 6 3 Protein of unknown function (DUF1138) Peptidase_U40 PF10464.9 AAZ36870.1 - 0.15 11.7 12.0 61 3.2 0.1 5.5 5 0 0 5 5 5 0 Peptidase U40 P68HR PF08061.11 AAZ36870.1 - 4.4 7.5 13.0 3.2e+02 1.6 0.1 6.4 6 0 0 6 6 6 0 P68HR (NUC004) repeat PMT PF02366.18 AAZ36871.1 - 6.8e-25 88.1 11.7 6.8e-25 88.1 11.7 2.1 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_2 PF13231.6 AAZ36871.1 - 8.2e-20 71.6 12.7 8.2e-20 71.6 12.7 3.5 4 0 0 4 4 4 2 Dolichyl-phosphate-mannose-protein mannosyltransferase HBM PF16591.5 AAZ36872.1 - 3.9e-79 265.7 17.0 3.9e-79 265.7 17.0 3.8 2 1 2 4 4 4 1 Helical bimodular sensor domain MCPsignal PF00015.21 AAZ36872.1 - 1.8e-42 145.1 26.3 1.8e-42 145.1 26.3 4.8 2 1 2 4 4 4 3 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AAZ36872.1 - 5.9e-11 42.6 1.4 5.9e-11 42.6 1.4 4.7 4 1 0 4 4 4 1 HAMP domain 4HB_MCP_1 PF12729.7 AAZ36872.1 - 0.0014 18.2 3.8 0.0014 18.2 3.8 5.5 4 2 0 5 5 5 2 Four helix bundle sensory module for signal transduction Syntaxin_2 PF14523.6 AAZ36872.1 - 0.24 11.8 26.3 0.44 10.9 0.9 6.1 3 2 2 6 6 6 0 Syntaxin-like protein DUF948 PF06103.11 AAZ36872.1 - 1.8 8.8 35.0 0.066 13.5 5.1 6.5 4 3 2 6 6 6 0 Bacterial protein of unknown function (DUF948) APG6_N PF17675.1 AAZ36872.1 - 7.8 7.0 22.3 0.66 10.5 0.5 4.0 3 2 0 3 3 3 0 Apg6 coiled-coil region Sec8_exocyst PF04048.14 AAZ36872.1 - 8.4 6.3 17.1 2 8.3 0.7 4.5 3 3 0 3 3 3 0 Sec8 exocyst complex component specific domain PseudoU_synth_2 PF00849.22 AAZ36874.1 - 1.7e-29 103.0 0.0 2.1e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 RNA pseudouridylate synthase Oxidored_FMN PF00724.20 AAZ36875.1 - 6e-91 305.2 0.0 7.9e-91 304.8 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.14 AAZ36875.1 - 1.1e-23 83.9 1.5 1.9e-23 83.2 1.5 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AAZ36875.1 - 3e-10 40.2 0.0 1.1e-09 38.4 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 AAZ36875.1 - 3.3e-08 32.6 0.6 1.3e-07 30.7 0.7 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 AAZ36875.1 - 3.9e-08 33.8 5.2 7.4e-05 23.2 0.4 4.3 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAZ36875.1 - 6.8e-08 32.1 0.6 0.004 16.4 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AAZ36875.1 - 5e-07 29.4 0.1 8e-07 28.7 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 AAZ36875.1 - 5.3e-06 26.4 1.5 0.00094 19.1 0.1 2.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 AAZ36875.1 - 1.5e-05 24.8 5.8 0.00016 21.4 0.9 3.7 4 0 0 4 4 4 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AAZ36875.1 - 1.7e-05 24.1 3.1 2.9e-05 23.3 2.0 1.9 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 AAZ36875.1 - 7.6e-05 22.1 3.4 0.0091 15.3 0.2 2.7 3 0 0 3 3 3 2 FAD binding domain GIDA PF01134.22 AAZ36875.1 - 0.00022 20.5 1.5 0.00022 20.5 1.5 2.0 2 1 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 AAZ36875.1 - 0.00029 20.2 0.0 0.00068 19.0 0.0 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Dus PF01207.17 AAZ36875.1 - 0.0005 19.3 0.1 0.00091 18.4 0.1 1.4 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) NAD_Gly3P_dh_N PF01210.23 AAZ36875.1 - 0.0012 18.9 0.4 0.043 13.8 0.0 3.1 3 0 0 3 3 3 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.17 AAZ36875.1 - 0.0017 17.7 0.7 0.0026 17.0 0.0 1.6 2 0 0 2 2 2 1 Thi4 family UDPG_MGDP_dh_N PF03721.14 AAZ36875.1 - 0.0024 17.5 0.2 0.01 15.4 0.0 2.0 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FMO-like PF00743.19 AAZ36875.1 - 0.0055 15.2 0.0 0.0097 14.4 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like 2-Hacid_dh_C PF02826.19 AAZ36875.1 - 0.044 13.1 0.1 5.6 6.3 0.0 2.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 AAZ36875.1 - 0.11 12.5 4.8 0.11 12.5 0.2 3.1 4 0 0 4 4 4 0 FAD-NAD(P)-binding Amino_oxidase PF01593.24 AAZ36875.1 - 0.12 11.6 0.2 0.29 10.4 0.1 1.6 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase AbiEi_2 PF09952.9 AAZ36876.1 - 2.4e-08 34.3 0.1 4.4e-08 33.5 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulator, AbiEi antitoxin, Type IV TA system MarR_2 PF12802.7 AAZ36876.1 - 0.029 14.3 0.0 0.078 12.9 0.0 1.7 1 0 0 1 1 1 0 MarR family Peptidase_S66 PF02016.15 AAZ36876.1 - 0.062 13.4 0.0 0.16 12.1 0.0 1.7 2 0 0 2 2 2 0 LD-carboxypeptidase N-terminal domain SBP_bac_3 PF00497.20 AAZ36877.1 - 1.3e-49 168.7 0.0 1.5e-49 168.5 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 AAZ36877.1 - 0.0012 19.0 0.0 0.031 14.5 0.0 2.3 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Peptidase_S49 PF01343.18 AAZ36878.1 - 4.7e-33 114.3 0.1 9.2e-33 113.4 0.1 1.4 1 0 0 1 1 1 1 Peptidase family S49 CLP_protease PF00574.23 AAZ36878.1 - 5.9e-05 23.0 0.1 0.00021 21.2 0.0 1.8 2 0 0 2 2 2 1 Clp protease SDH_sah PF01972.16 AAZ36878.1 - 0.073 12.1 0.1 0.12 11.3 0.1 1.3 1 0 0 1 1 1 0 Serine dehydrogenase proteinase AAA_18 PF13238.6 AAZ36879.1 - 0.016 15.8 0.0 0.035 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 AAZ36879.1 - 0.017 15.5 0.1 0.032 14.6 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain DUF3877 PF12993.7 AAZ36879.1 - 0.027 14.4 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) T2SSE PF00437.20 AAZ36879.1 - 0.037 13.1 0.0 0.063 12.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Rhodanese PF00581.20 AAZ36879.1 - 0.049 14.2 0.0 0.3 11.6 0.0 2.2 1 1 0 1 1 1 0 Rhodanese-like domain Amidohydro_3 PF07969.11 AAZ36880.1 - 8.7e-11 41.9 3.3 1e-07 31.8 0.1 3.1 1 1 1 3 3 3 3 Amidohydrolase family Amidohydro_1 PF01979.20 AAZ36880.1 - 0.0003 20.2 0.3 0.0019 17.6 0.3 2.4 1 1 0 1 1 1 1 Amidohydrolase family AcetylCoA_hyd_C PF13336.6 AAZ36881.1 - 6.7e-46 156.0 0.1 1.7e-45 154.7 0.0 1.7 2 0 0 2 2 2 1 Acetyl-CoA hydrolase/transferase C-terminal domain Flu_M1 PF00598.19 AAZ36881.1 - 0.16 11.5 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Influenza Matrix protein (M1) LysR_substrate PF03466.20 AAZ36882.1 - 2.6e-38 131.5 0.3 4.2e-38 130.8 0.3 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ36882.1 - 2e-18 66.1 0.4 4e-18 65.1 0.4 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_24 PF13412.6 AAZ36882.1 - 0.081 12.5 0.3 0.56 9.8 0.3 2.3 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding ketoacyl-synt PF00109.26 AAZ36883.1 - 2.6e-71 240.1 0.5 1.8e-70 237.4 0.3 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 AAZ36883.1 - 4.6e-55 187.3 0.2 7.5e-55 186.7 0.2 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 AAZ36883.1 - 5.2e-45 153.6 0.5 1.2e-44 152.4 0.5 1.7 1 0 0 1 1 1 1 KR domain Methyltransf_12 PF08242.12 AAZ36883.1 - 4.2e-39 133.3 0.1 4.9e-20 72.1 0.0 3.5 4 0 0 4 4 2 2 Methyltransferase domain Ketoacyl-synt_C PF02801.22 AAZ36883.1 - 7.8e-38 129.1 0.1 2.1e-37 127.7 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Condensation PF00668.20 AAZ36883.1 - 2.3e-32 112.3 0.0 4.6e-32 111.3 0.0 1.4 1 0 0 1 1 1 1 Condensation domain Methyltransf_23 PF13489.6 AAZ36883.1 - 3.9e-24 85.3 0.2 7.7e-11 42.1 0.0 3.3 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_25 PF13649.6 AAZ36883.1 - 2.1e-22 79.6 0.0 4.1e-10 40.2 0.0 3.8 3 0 0 3 3 3 2 Methyltransferase domain PP-binding PF00550.25 AAZ36883.1 - 1.8e-20 73.1 2.4 1.5e-09 38.1 0.4 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site Thioesterase PF00975.20 AAZ36883.1 - 3.4e-19 69.9 7.1 4e-19 69.7 2.8 2.9 2 1 0 2 2 2 1 Thioesterase domain Methyltransf_11 PF08241.12 AAZ36883.1 - 1.4e-18 67.4 0.0 3.2e-08 34.1 0.0 2.9 2 0 0 2 2 2 2 Methyltransferase domain KAsynt_C_assoc PF16197.5 AAZ36883.1 - 3.9e-14 53.0 0.0 5.7e-13 49.3 0.0 2.7 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Methyltransf_31 PF13847.6 AAZ36883.1 - 6.1e-14 52.1 0.0 6.4e-07 29.3 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 AAZ36883.1 - 6.3e-08 32.2 0.0 0.00073 18.9 0.0 2.3 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family DUF938 PF06080.12 AAZ36883.1 - 9.8e-08 32.0 0.0 0.0032 17.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF938) adh_short PF00106.25 AAZ36883.1 - 1.4e-07 31.2 0.0 1.3e-06 28.0 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase Thiolase_N PF00108.23 AAZ36883.1 - 1.1e-06 28.2 0.7 2.1e-06 27.3 0.7 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.9 AAZ36883.1 - 1.7e-06 27.9 0.0 0.049 13.4 0.0 2.6 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_33 PF10017.9 AAZ36883.1 - 8.9e-05 21.8 0.0 0.044 12.9 0.0 3.0 3 0 0 3 3 3 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_24 PF13578.6 AAZ36883.1 - 9.5e-05 23.4 0.6 0.046 14.8 0.0 4.0 3 1 0 3 3 2 1 Methyltransferase domain DREV PF05219.12 AAZ36883.1 - 0.00047 19.3 0.0 0.05 12.7 0.0 2.3 2 0 0 2 2 2 1 DREV methyltransferase Methyltransf_2 PF00891.18 AAZ36883.1 - 0.0053 16.1 0.0 0.21 10.8 0.0 2.5 2 0 0 2 2 2 1 O-methyltransferase domain Hydrolase_4 PF12146.8 AAZ36883.1 - 0.015 14.5 0.1 0.091 12.0 0.0 2.4 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Transferase PF02458.15 AAZ36883.1 - 0.18 10.4 0.0 0.28 9.8 0.0 1.2 1 0 0 1 1 1 0 Transferase family RrnaAD PF00398.20 AAZ36883.1 - 0.25 10.4 0.1 1 8.3 0.0 1.8 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase CN_hydrolase PF00795.22 AAZ36884.1 - 4.9e-33 114.6 0.0 7e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase TruB_C PF09142.11 AAZ36884.1 - 0.0088 15.8 0.2 0.028 14.2 0.0 2.0 2 0 0 2 2 2 1 tRNA Pseudouridine synthase II, C terminal HATPase_c PF02518.26 AAZ36885.1 - 6.2e-11 42.8 0.0 1.1e-10 42.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAZ36885.1 - 7.9e-06 25.8 0.9 7e-05 22.8 0.0 2.6 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 AAZ36885.1 - 0.00011 22.2 0.0 0.0002 21.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_5 PF14501.6 AAZ36885.1 - 0.0031 17.4 0.0 0.0097 15.8 0.0 1.8 1 1 0 1 1 1 1 GHKL domain HAMP PF00672.25 AAZ36885.1 - 0.017 15.5 0.6 0.19 12.1 0.4 2.6 2 0 0 2 2 2 0 HAMP domain HATPase_c_3 PF13589.6 AAZ36885.1 - 0.021 14.6 0.0 0.038 13.8 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CorA PF01544.18 AAZ36885.1 - 0.029 13.7 0.1 0.045 13.1 0.1 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein H2O2_YaaD PF03883.14 AAZ36886.1 - 1.2e-89 299.8 0.1 1.4e-89 299.7 0.1 1.0 1 0 0 1 1 1 1 Peroxide stress protein YaaA PHB_acc PF05233.13 AAZ36886.1 - 0.019 15.0 0.4 3.5 7.7 0.0 2.5 2 0 0 2 2 2 0 PHB accumulation regulatory domain MFS_1 PF07690.16 AAZ36887.1 - 1.7e-48 165.4 43.2 1.7e-48 165.4 43.2 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 AAZ36887.1 - 3.3e-07 29.2 8.7 3.3e-07 29.2 8.7 2.9 1 1 0 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.24 AAZ36887.1 - 1.4e-06 27.4 10.7 1.4e-06 27.4 10.7 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 AAZ36887.1 - 0.00075 17.9 0.1 0.00075 17.9 0.1 2.8 2 2 2 4 4 4 2 Organic Anion Transporter Polypeptide (OATP) family DUF3084 PF11283.8 AAZ36887.1 - 0.018 15.0 5.7 0.096 12.7 0.6 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3084) Folate_carrier PF01770.18 AAZ36887.1 - 0.051 12.3 0.1 0.095 11.4 0.1 1.4 1 0 0 1 1 1 0 Reduced folate carrier Pox_A14 PF05767.12 AAZ36887.1 - 8.2 6.7 8.4 0.77 9.9 0.1 3.4 4 0 0 4 4 4 0 Poxvirus virion envelope protein A14 HATPase_c PF02518.26 AAZ36888.1 - 2.9e-20 72.9 0.0 5.2e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase dCache_1 PF02743.18 AAZ36888.1 - 9.2e-11 42.0 1.0 3.1e-10 40.3 0.0 2.0 2 0 0 2 2 2 1 Cache domain HATPase_c_3 PF13589.6 AAZ36888.1 - 8.3e-06 25.7 0.0 1.5e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAZ36888.1 - 0.00011 22.2 0.3 0.00011 22.2 0.3 3.3 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 AAZ36888.1 - 0.00072 19.4 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 GHKL domain CopD PF05425.13 AAZ36888.1 - 0.56 10.6 4.1 1.2 9.6 0.2 3.1 3 0 0 3 3 3 0 Copper resistance protein D Amidase_2 PF01510.25 AAZ36889.1 - 6.7e-29 100.9 0.0 8.3e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase HDOD PF08668.12 AAZ36890.1 - 2e-50 171.0 0.0 2.4e-50 170.7 0.0 1.1 1 0 0 1 1 1 1 HDOD domain HD PF01966.22 AAZ36890.1 - 0.0042 17.3 0.0 0.023 14.9 0.0 2.2 1 1 0 1 1 1 1 HD domain RecA PF00154.21 AAZ36891.1 - 1.3e-143 477.2 2.5 1.6e-143 476.9 2.5 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Rad51 PF08423.11 AAZ36891.1 - 2.2e-12 46.8 0.5 9.6e-12 44.7 0.5 1.8 1 1 0 1 1 1 1 Rad51 ATPase PF06745.13 AAZ36891.1 - 1.4e-08 34.4 1.8 1.2e-06 28.1 1.8 2.8 1 1 0 1 1 1 1 KaiC ATPase_2 PF01637.18 AAZ36891.1 - 0.00011 22.1 0.0 0.0002 21.3 0.0 1.4 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA PF00004.29 AAZ36891.1 - 0.0014 19.1 0.2 0.0033 17.8 0.1 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 AAZ36891.1 - 0.0027 17.5 0.0 0.0046 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain CobU PF02283.16 AAZ36891.1 - 0.006 16.2 0.0 0.0096 15.5 0.0 1.3 1 0 0 1 1 1 1 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_25 PF13481.6 AAZ36891.1 - 0.01 15.4 1.1 0.13 11.9 0.0 2.3 1 1 1 2 2 2 0 AAA domain MobB PF03205.14 AAZ36891.1 - 0.017 15.0 0.0 0.077 12.9 0.0 2.1 1 1 1 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_35 PF14516.6 AAZ36891.1 - 0.029 13.2 0.0 0.048 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_16 PF13191.6 AAZ36891.1 - 0.089 13.2 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain TK PF00265.18 AAZ36891.1 - 0.095 12.6 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Thymidine kinase AAA_22 PF13401.6 AAZ36891.1 - 0.16 12.2 0.0 0.42 10.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain Endonuclease_1 PF04231.13 AAZ36892.1 - 3.8e-35 121.6 1.0 6.7e-35 120.9 1.0 1.3 1 1 0 1 1 1 1 Endonuclease I Alpha-amylase PF00128.24 AAZ36893.1 - 3.8e-71 240.4 0.0 1.1e-70 238.9 0.0 1.7 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 AAZ36893.1 - 7e-28 96.6 0.0 1.5e-27 95.5 0.0 1.6 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain Mak_N_cap PF18085.1 AAZ36893.1 - 2e-09 38.4 0.1 8.2e-09 36.4 0.0 2.2 2 0 0 2 2 2 1 Maltokinase N-terminal cap domain hDGE_amylase PF14701.6 AAZ36893.1 - 0.16 11.1 0.0 0.31 10.1 0.0 1.4 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain PspB PF06667.12 AAZ36893.1 - 0.61 10.2 2.5 9.2 6.4 1.2 2.9 3 0 0 3 3 3 0 Phage shock protein B PTA_PTB PF01515.19 AAZ36894.1 - 6.8e-114 380.5 0.0 9.8e-114 379.9 0.0 1.2 1 0 0 1 1 1 1 Phosphate acetyl/butaryl transferase AAA_26 PF13500.6 AAZ36894.1 - 2.4e-38 132.0 0.0 1.7e-37 129.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain DRTGG PF07085.12 AAZ36894.1 - 2.4e-30 104.4 0.0 7.2e-30 102.9 0.0 1.9 1 0 0 1 1 1 1 DRTGG domain CbiA PF01656.23 AAZ36894.1 - 1.2e-05 25.4 0.0 0.00028 20.9 0.0 3.0 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain UreE_C PF05194.12 AAZ36895.1 - 3.8e-27 94.6 0.2 5.4e-27 94.1 0.2 1.2 1 0 0 1 1 1 1 UreE urease accessory protein, C-terminal domain UreE_N PF02814.15 AAZ36895.1 - 6.5e-18 64.1 0.0 1e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 UreE urease accessory protein, N-terminal domain Aminotran_5 PF00266.19 AAZ36896.1 - 6.8e-51 173.3 0.0 7.8e-51 173.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Gln-synt_C PF00120.24 AAZ36897.1 - 1.3e-107 359.8 0.0 1.6e-107 359.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 AAZ36897.1 - 0.022 14.5 0.2 0.048 13.4 0.2 1.5 1 0 0 1 1 1 0 Glutamine synthetase, beta-Grasp domain Fer2_2 PF01799.20 AAZ36898.1 - 2.1e-30 104.5 0.2 2.1e-30 104.5 0.2 2.1 2 0 0 2 2 2 1 [2Fe-2S] binding domain Fer2 PF00111.27 AAZ36898.1 - 2.3e-06 27.5 0.5 2.3e-06 27.5 0.5 1.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 AAZ36898.1 - 0.0003 20.7 0.2 0.00059 19.8 0.2 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain TAT_signal PF10518.9 AAZ36898.1 - 0.0046 16.7 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence DUF2946 PF11162.8 AAZ36898.1 - 1.1 9.9 6.9 1 10.0 0.4 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2946) DUF5629 PF18629.1 AAZ36899.1 - 2.2e-23 82.6 4.1 2.7e-15 56.7 0.5 2.1 1 1 1 2 2 2 2 Family of unknown function (DUF5629) Dak2 PF02734.17 AAZ36900.1 - 2.4e-50 170.8 2.0 2.8e-50 170.6 2.0 1.0 1 0 0 1 1 1 1 DAK2 domain Hydrolase_3 PF08282.12 AAZ36901.1 - 0.00058 19.7 2.6 0.00076 19.3 2.6 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAZ36901.1 - 0.044 14.1 3.8 0.046 14.0 2.4 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF759 PF05537.11 AAZ36901.1 - 0.093 11.6 0.0 0.1 11.5 0.0 1.0 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF759) TPR_21 PF09976.9 AAZ36902.1 - 2.2e-61 207.0 10.6 2.5e-61 206.8 10.6 1.0 1 0 0 1 1 1 1 Tetratricopeptide repeat-like domain TPR_14 PF13428.6 AAZ36902.1 - 7e-05 23.3 10.3 0.37 11.7 0.3 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 AAZ36902.1 - 0.00026 20.8 3.6 0.13 12.4 0.3 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 AAZ36902.1 - 0.0005 19.7 2.1 0.026 14.2 0.3 3.2 3 0 0 3 3 3 1 TPR repeat TPR_19 PF14559.6 AAZ36902.1 - 0.00056 20.4 16.0 0.005 17.3 5.2 3.2 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 AAZ36902.1 - 0.00078 19.2 0.9 0.078 12.8 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 AAZ36902.1 - 0.0023 18.0 1.0 0.014 15.5 0.3 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 AAZ36902.1 - 0.0055 17.3 14.6 0.0064 17.1 3.4 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat NARP1 PF12569.8 AAZ36902.1 - 0.0073 15.3 0.9 0.024 13.5 0.4 1.8 1 1 1 2 2 2 1 NMDA receptor-regulated protein 1 TPR_12 PF13424.6 AAZ36902.1 - 0.014 15.7 6.9 1.4 9.3 0.3 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 AAZ36902.1 - 0.017 15.7 9.1 7 7.6 0.7 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 AAZ36902.1 - 0.044 13.8 5.9 2.4 8.4 0.2 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 AAZ36902.1 - 0.064 13.5 2.3 0.76 10.0 0.5 2.8 1 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 AAZ36902.1 - 0.13 12.9 8.8 9.4 7.1 0.3 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 AAZ36902.1 - 1.3 9.0 6.1 1.6 8.7 0.2 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat LolA PF03548.15 AAZ36903.1 - 3.6e-56 189.4 1.4 4.2e-56 189.2 1.4 1.0 1 0 0 1 1 1 1 Outer membrane lipoprotein carrier protein LolA DUF2092 PF09865.9 AAZ36903.1 - 5.8e-05 22.6 0.0 0.034 13.5 0.0 2.2 2 0 0 2 2 2 2 Predicted periplasmic protein (DUF2092) SpoU_methylase PF00588.19 AAZ36904.1 - 1e-31 110.0 0.0 1.1e-31 109.9 0.0 1.0 1 0 0 1 1 1 1 SpoU rRNA Methylase family Malate_DH PF12434.8 AAZ36904.1 - 0.048 13.7 0.1 0.086 12.9 0.1 1.3 1 0 0 1 1 1 0 Malate dehydrogenase enzyme ParD_like PF11903.8 AAZ36905.1 - 6e-26 90.3 0.1 7e-26 90.1 0.1 1.1 1 0 0 1 1 1 1 ParD-like antitoxin of type II bacterial toxin-antitoxin system ABC_tran PF00005.27 AAZ36906.1 - 5.1e-27 95.0 0.0 7.9e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 AAZ36906.1 - 4e-06 26.8 0.1 0.00072 19.5 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 AAZ36906.1 - 3.7e-05 24.2 0.7 8.9e-05 22.9 0.7 1.8 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 AAZ36906.1 - 0.00026 20.4 0.2 0.00051 19.5 0.2 1.5 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_21 PF13304.6 AAZ36906.1 - 0.00036 20.5 0.4 0.03 14.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 AAZ36906.1 - 0.00075 19.8 0.0 0.0017 18.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAZ36906.1 - 0.0012 18.6 0.7 0.0025 17.5 0.1 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.6 AAZ36906.1 - 0.0015 18.8 0.0 0.0025 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 AAZ36906.1 - 0.0036 17.8 0.0 0.0055 17.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AAZ36906.1 - 0.0062 16.7 0.0 0.013 15.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 AAZ36906.1 - 0.0082 16.2 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_30 PF13604.6 AAZ36906.1 - 0.0082 15.9 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 AAZ36906.1 - 0.016 14.8 0.5 0.066 12.8 0.3 2.0 1 1 1 2 2 2 0 AAA domain NACHT PF05729.12 AAZ36906.1 - 0.016 15.1 1.2 0.045 13.7 1.2 2.0 1 1 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 AAZ36906.1 - 0.019 14.7 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AAZ36906.1 - 0.023 15.2 0.0 0.049 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 AAZ36906.1 - 0.027 13.7 0.0 3.2 6.9 0.0 2.1 2 0 0 2 2 2 0 KAP family P-loop domain AAA_5 PF07728.14 AAZ36906.1 - 0.058 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 AAZ36906.1 - 0.095 13.1 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 AAZ36906.1 - 0.098 12.4 0.2 0.45 10.2 0.1 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein T2SSE PF00437.20 AAZ36906.1 - 0.12 11.4 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.19 AAZ36906.1 - 0.13 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 AAZ36906.1 - 0.15 11.5 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 AAZ36906.1 - 0.16 12.4 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ATP_bind_1 PF03029.17 AAZ36906.1 - 0.21 11.3 0.0 0.34 10.7 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DUF87 PF01935.17 AAZ36906.1 - 0.23 11.5 0.0 0.42 10.7 0.0 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain NTPase_1 PF03266.15 AAZ36906.1 - 0.24 11.3 0.0 0.55 10.1 0.0 1.6 1 0 0 1 1 1 0 NTPase SRPRB PF09439.10 AAZ36906.1 - 0.25 10.7 0.0 0.42 10.0 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Lysine_decarbox PF03641.14 AAZ36908.1 - 3.5e-28 98.3 0.0 5.8e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 AAZ36908.1 - 3.1e-14 52.9 0.0 4.6e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 SLOG cluster4 family Methyltrn_RNA_4 PF09936.9 AAZ36908.1 - 0.0095 15.8 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 1 SAM-dependent RNA methyltransferase DNA_processg_A PF02481.15 AAZ36908.1 - 0.013 14.7 0.1 0.022 14.0 0.1 1.3 1 0 0 1 1 1 0 DNA recombination-mediator protein A STALD PF18185.1 AAZ36908.1 - 0.17 11.2 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Sir2- and TIR-associating SLOG family Phosphoesterase PF04185.14 AAZ36909.1 - 2.6e-102 342.7 0.1 3.3e-102 342.3 0.1 1.1 1 0 0 1 1 1 1 Phosphoesterase family Sulfatase PF00884.23 AAZ36909.1 - 8.1e-06 25.4 0.1 1.4e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 Sulfatase TAT_signal PF10518.9 AAZ36909.1 - 0.00026 20.7 1.0 0.00053 19.7 1.0 1.6 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence UCR_Fe-S_N PF10399.9 AAZ36909.1 - 0.038 13.3 0.0 0.082 12.3 0.0 1.5 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal ACP_syn_III_C PF08541.10 AAZ36910.1 - 6.4e-25 87.1 0.0 4e-24 84.6 0.0 2.1 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 AAZ36910.1 - 3.4e-19 68.5 0.2 7e-19 67.5 0.2 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 AAZ36910.1 - 0.0001 22.0 6.9 0.019 14.6 4.1 3.1 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.23 AAZ36910.1 - 0.00017 21.0 0.4 0.00037 19.9 0.2 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain FAE1_CUT1_RppA PF08392.12 AAZ36910.1 - 0.011 15.0 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 FAE1/Type III polyketide synthase-like protein QH-AmDH_gamma PF08992.11 AAZ36911.1 - 0.15 12.0 0.0 0.16 12.0 0.0 1.1 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, gamma subunit DUF520 PF04461.13 AAZ36912.1 - 3.3e-61 206.1 4.3 3.7e-61 205.9 4.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF520) Bacillus_HBL PF05791.11 AAZ36912.1 - 0.013 15.3 0.1 0.034 14.0 0.1 1.7 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DinI PF06183.13 AAZ36912.1 - 0.048 14.0 0.4 0.15 12.5 0.2 1.9 2 0 0 2 2 2 0 DinI-like family DUF3194 PF11419.8 AAZ36912.1 - 0.12 12.7 0.2 0.12 12.7 0.2 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3194) 4HBT_3 PF13622.6 AAZ36914.1 - 3.2e-61 207.7 0.1 3.8e-61 207.5 0.1 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 AAZ36914.1 - 1.2e-39 135.1 0.0 1.1e-29 102.9 0.0 3.0 2 1 0 2 2 2 2 Acyl-CoA thioesterase S4 PF01479.25 AAZ36915.1 - 3.3e-06 26.7 0.0 7.9e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 S4 domain PseudoU_synth_2 PF00849.22 AAZ36915.1 - 0.0011 19.0 0.0 0.0015 18.6 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase ZapB PF06005.12 AAZ36916.1 - 8.5e-06 26.1 9.8 1.1e-05 25.8 9.8 1.1 1 0 0 1 1 1 1 Cell division protein ZapB SHE3 PF17078.5 AAZ36916.1 - 0.0017 18.1 2.2 0.0019 18.0 2.2 1.1 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 APG6_N PF17675.1 AAZ36916.1 - 0.0019 18.7 9.2 0.0027 18.2 9.2 1.1 1 0 0 1 1 1 1 Apg6 coiled-coil region YabA PF06156.13 AAZ36916.1 - 0.0036 17.9 3.6 0.0045 17.6 3.6 1.3 1 0 0 1 1 1 1 Initiation control protein YabA DivIVA PF05103.13 AAZ36916.1 - 0.0043 17.1 4.0 0.0049 16.9 4.0 1.2 1 0 0 1 1 1 1 DivIVA protein EzrA PF06160.12 AAZ36916.1 - 0.0047 15.2 3.0 0.0052 15.0 3.0 1.0 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA NRBF2 PF08961.10 AAZ36916.1 - 0.0049 16.5 2.1 0.0059 16.2 2.1 1.3 1 1 0 1 1 1 1 Nuclear receptor-binding factor 2, autophagy regulator bZIP_1 PF00170.21 AAZ36916.1 - 0.0061 16.6 3.9 0.01 15.9 3.9 1.5 1 0 0 1 1 1 1 bZIP transcription factor Troponin PF00992.20 AAZ36916.1 - 0.0066 16.8 1.3 0.0079 16.5 1.3 1.1 1 0 0 1 1 1 1 Troponin HAP1_N PF04849.13 AAZ36916.1 - 0.0078 15.5 6.8 0.011 15.0 6.1 1.6 1 1 0 1 1 1 1 HAP1 N-terminal conserved region ATG16 PF08614.11 AAZ36916.1 - 0.0085 16.3 8.3 0.011 15.9 8.3 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) T3SSipB PF16535.5 AAZ36916.1 - 0.014 15.9 6.8 0.016 15.7 6.8 1.0 1 0 0 1 1 1 0 Type III cell invasion protein SipB DUF3829 PF12889.7 AAZ36916.1 - 0.015 14.8 0.8 0.017 14.7 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) Cnn_1N PF07989.11 AAZ36916.1 - 0.021 15.0 5.3 0.034 14.3 5.3 1.4 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 Phage_lysis PF03245.13 AAZ36916.1 - 0.027 14.6 4.2 0.031 14.4 4.2 1.2 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein DivIC PF04977.15 AAZ36916.1 - 0.033 14.0 4.8 0.033 14.0 4.8 2.1 1 1 1 2 2 2 0 Septum formation initiator Macoilin PF09726.9 AAZ36916.1 - 0.039 12.5 4.1 0.039 12.5 4.1 1.0 1 0 0 1 1 1 0 Macoilin family Uso1_p115_C PF04871.13 AAZ36916.1 - 0.051 13.9 6.8 0.056 13.8 6.8 1.1 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Snapin_Pallidin PF14712.6 AAZ36916.1 - 0.058 13.8 4.8 0.072 13.5 4.8 1.1 1 0 0 1 1 1 0 Snapin/Pallidin CENP-H PF05837.12 AAZ36916.1 - 0.084 13.3 4.9 0.097 13.1 4.9 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) ERM PF00769.19 AAZ36916.1 - 0.085 12.7 9.8 0.094 12.5 9.8 1.0 1 0 0 1 1 1 0 Ezrin/radixin/moesin family UPF0242 PF06785.11 AAZ36916.1 - 0.18 11.9 5.3 0.2 11.7 5.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMF_DNA_bd PF12329.8 AAZ36916.1 - 0.2 11.7 8.6 0.49 10.4 8.6 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding KxDL PF10241.9 AAZ36916.1 - 0.23 11.8 4.7 0.3 11.4 4.7 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein DUF2203 PF09969.9 AAZ36916.1 - 0.29 11.9 2.8 0.33 11.7 2.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) bZIP_2 PF07716.15 AAZ36916.1 - 0.48 10.5 7.7 0.29 11.3 1.7 2.5 2 1 0 2 2 2 0 Basic region leucine zipper FlaC_arch PF05377.11 AAZ36916.1 - 0.63 10.5 3.2 4.3 7.8 0.3 2.2 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) SlyX PF04102.12 AAZ36916.1 - 3.3 8.4 9.4 13 6.5 9.4 1.9 1 1 0 1 1 1 0 SlyX Spc24 PF08286.11 AAZ36916.1 - 3.7 7.8 7.3 6.9 7.0 7.3 1.5 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 RcpB PF16971.5 AAZ36917.1 - 0.009 15.9 0.1 0.011 15.7 0.1 1.1 1 0 0 1 1 1 1 Rough colony protein B, tight adherence - tad - subunit N_methyl PF07963.12 AAZ36918.1 - 2.2e-08 33.3 0.4 3.4e-08 32.7 0.4 1.3 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif MSP1a PF11670.8 AAZ36918.1 - 0.04 13.2 0.1 0.069 12.4 0.1 1.4 2 0 0 2 2 2 0 Major surface protein 1a (MSP1a) PulG PF11773.8 AAZ36918.1 - 0.26 11.1 2.6 0.49 10.3 2.6 1.4 1 0 0 1 1 1 0 Type II secretory pathway pseudopilin CSD PF00313.22 AAZ36919.1 - 6.2e-25 86.8 0.0 7.5e-25 86.6 0.0 1.1 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 AAZ36919.1 - 0.019 14.6 0.2 0.026 14.2 0.2 1.3 1 0 0 1 1 1 0 Ribonuclease B OB domain CSD2 PF17876.1 AAZ36919.1 - 0.048 13.8 0.0 0.065 13.4 0.0 1.1 1 0 0 1 1 1 0 Cold shock domain Peptidase_M23 PF01551.22 AAZ36919.1 - 0.079 13.2 0.0 0.12 12.6 0.0 1.3 1 1 0 1 1 1 0 Peptidase family M23 Aminotran_1_2 PF00155.21 AAZ36920.1 - 1.5e-34 119.8 0.0 1.7e-34 119.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II GntR PF00392.21 AAZ36920.1 - 4e-14 52.0 0.3 2.7e-13 49.4 0.0 2.5 3 0 0 3 3 3 1 Bacterial regulatory proteins, gntR family HTH_41 PF14502.6 AAZ36920.1 - 0.00031 20.4 0.0 0.00064 19.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain IcmF-related PF06761.12 AAZ36920.1 - 0.035 13.6 0.1 0.059 12.8 0.1 1.3 1 0 0 1 1 1 0 Intracellular multiplication and human macrophage-killing MLD PF11647.8 AAZ36921.1 - 2.3e-27 95.1 0.1 2.6e-13 50.0 0.0 2.6 2 0 0 2 2 2 2 Membrane Localization Domain YscK PF06578.12 AAZ36921.1 - 0.028 13.9 0.3 0.1 12.1 0.0 2.0 2 0 0 2 2 2 0 YOP proteins translocation protein K (YscK) LpxK PF02606.14 AAZ36922.1 - 1.4e-104 349.8 0.0 1.6e-104 349.6 0.0 1.0 1 0 0 1 1 1 1 Tetraacyldisaccharide-1-P 4'-kinase MobB PF03205.14 AAZ36922.1 - 0.00062 19.7 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.27 AAZ36923.1 - 2e-33 115.8 0.0 2.9e-33 115.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAZ36923.1 - 4.7e-11 43.1 0.1 1.7e-05 24.8 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAZ36923.1 - 7.6e-07 28.8 0.3 6.6e-06 25.7 0.3 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAZ36923.1 - 0.0005 19.7 0.1 0.00093 18.9 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.6 AAZ36923.1 - 0.00053 18.8 0.0 0.13 10.9 0.0 2.1 1 1 1 2 2 2 2 AAA domain ABC_ATPase PF09818.9 AAZ36923.1 - 0.0022 16.9 0.0 1.6 7.4 0.0 2.3 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_24 PF13479.6 AAZ36923.1 - 0.0061 16.3 0.0 0.0088 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 AAZ36923.1 - 0.0094 15.7 0.0 0.049 13.3 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain G-alpha PF00503.20 AAZ36923.1 - 0.011 14.9 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_23 PF13476.6 AAZ36923.1 - 0.016 15.7 0.2 0.031 14.8 0.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AAZ36923.1 - 0.023 14.9 0.0 0.042 14.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain PRK PF00485.18 AAZ36923.1 - 0.029 14.1 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 AAZ36923.1 - 0.035 14.5 0.1 0.065 13.6 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 AAZ36923.1 - 0.039 14.2 0.0 0.077 13.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 AAZ36923.1 - 0.053 13.4 0.1 0.11 12.4 0.1 1.6 2 0 0 2 2 2 0 RsgA GTPase Mg_chelatase PF01078.21 AAZ36923.1 - 0.1 12.0 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SbcCD_C PF13558.6 AAZ36923.1 - 0.11 12.8 0.2 2.3 8.5 0.2 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.17 AAZ36923.1 - 0.23 11.5 0.7 0.78 9.8 0.3 1.9 1 1 1 2 2 2 0 Helicase HerA, central domain LysR_substrate PF03466.20 AAZ36924.1 - 5.7e-38 130.4 5.4 8.5e-38 129.8 5.4 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ36924.1 - 3e-16 59.1 3.4 7.1e-16 57.9 3.4 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family UPF0259 PF06790.11 AAZ36925.1 - 2.5e-09 37.3 13.4 8.3e-08 32.3 9.7 2.1 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0259) DUF975 PF06161.11 AAZ36925.1 - 0.048 13.5 14.4 0.016 15.0 9.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF975) GPDPase_memb PF10110.9 AAZ36925.1 - 0.56 8.9 14.6 0.049 12.4 9.6 1.7 2 0 0 2 2 2 0 Membrane domain of glycerophosphoryl diester phosphodiesterase DUF3958 PF13125.6 AAZ36926.1 - 0.1 12.8 0.1 0.95 9.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) adh_short PF00106.25 AAZ36927.1 - 6.5e-51 172.6 0.4 2.8e-50 170.5 0.2 2.0 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAZ36927.1 - 3.6e-35 121.6 0.1 7.2e-35 120.6 0.1 1.5 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 AAZ36927.1 - 6.9e-08 32.3 0.1 1.3e-07 31.4 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 AAZ36927.1 - 1.2e-07 31.8 0.3 1.8e-06 28.0 0.2 2.4 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 AAZ36927.1 - 4.2e-05 23.1 0.0 0.0097 15.3 0.0 2.9 2 1 0 3 3 3 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 AAZ36927.1 - 0.0056 16.6 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 AAZ36927.1 - 0.11 11.9 0.3 0.25 10.7 0.3 1.6 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase BPD_transp_1 PF00528.22 AAZ36928.1 - 2.2e-10 40.6 29.0 6.2e-10 39.1 24.2 3.0 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component PEP_mutase PF13714.6 AAZ36929.1 - 9.6e-51 172.5 5.0 1.1e-50 172.3 5.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 AAZ36929.1 - 1.9e-12 46.5 0.7 2.5e-12 46.1 0.7 1.1 1 0 0 1 1 1 1 Isocitrate lyase family DUF4936 PF16290.5 AAZ36929.1 - 0.0048 17.5 0.8 0.022 15.4 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4936) MraZ PF02381.18 AAZ36929.1 - 0.073 13.1 0.0 0.26 11.3 0.0 1.8 2 0 0 2 2 2 0 MraZ protein, putative antitoxin-like MraZ PF02381.18 AAZ36930.1 - 3.4e-34 116.6 0.1 1.1e-16 60.6 0.0 2.1 2 0 0 2 2 2 2 MraZ protein, putative antitoxin-like LysR_substrate PF03466.20 AAZ36931.1 - 5.4e-07 29.2 0.0 5.9e-07 29.1 0.0 1.0 1 0 0 1 1 1 1 LysR substrate binding domain DHFR_1 PF00186.19 AAZ36932.1 - 5.2e-55 185.5 0.0 5.8e-55 185.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrofolate reductase Aminotran_3 PF00202.21 AAZ36933.1 - 5.1e-126 420.6 0.0 5.9e-126 420.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III SPOR PF05036.13 AAZ36934.1 - 1.6e-17 63.6 0.2 2.6e-17 62.9 0.2 1.3 1 0 0 1 1 1 1 Sporulation related domain DUF4813 PF16072.5 AAZ36934.1 - 0.24 11.0 36.6 0.31 10.7 36.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) LrgB PF04172.16 AAZ36935.1 - 4.4e-73 245.4 19.2 5e-73 245.2 19.2 1.0 1 0 0 1 1 1 1 LrgB-like family Phage_r1t_holin PF16945.5 AAZ36935.1 - 0.38 11.0 6.6 2.1 8.6 0.7 2.6 1 1 1 2 2 2 0 Putative lactococcus lactis phage r1t holin Response_reg PF00072.24 AAZ36936.1 - 1.5e-30 105.6 0.0 2.5e-30 104.9 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAZ36936.1 - 5.2e-18 64.9 0.0 9.7e-18 64.0 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal FleQ PF06490.11 AAZ36936.1 - 0.00025 21.4 0.0 0.00039 20.7 0.0 1.4 1 0 0 1 1 1 1 Flagellar regulatory protein FleQ Aminotran_3 PF00202.21 AAZ36936.1 - 0.21 10.2 0.0 0.29 9.8 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-III Phage_integrase PF00589.22 AAZ36937.1 - 1.6e-21 76.8 0.3 3.3e-21 75.8 0.3 1.6 1 0 0 1 1 1 1 Phage integrase family Integrase_1 PF12835.7 AAZ36937.1 - 1.3e-05 25.3 0.0 3.3e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Integrase Phage_int_SAM_5 PF13102.6 AAZ36937.1 - 5.7e-05 23.4 0.1 0.00019 21.7 0.1 1.9 2 0 0 2 2 2 1 Phage integrase SAM-like domain Phage_int_SAM_1 PF02899.17 AAZ36937.1 - 0.012 15.9 0.2 0.07 13.4 0.1 2.4 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain LIP PF03583.14 AAZ36938.1 - 2e-23 83.1 0.0 5.2e-23 81.8 0.0 1.6 1 1 0 1 1 1 1 Secretory lipase Hydrolase_4 PF12146.8 AAZ36938.1 - 6.7e-08 32.1 0.0 1.1e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AAZ36938.1 - 3.1e-07 31.2 2.0 3.3e-07 31.1 0.8 1.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 AAZ36938.1 - 4.6e-05 23.4 0.1 0.0039 17.1 0.1 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 AAZ36938.1 - 0.00059 19.4 0.2 0.66 9.4 0.0 2.6 2 1 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 AAZ36938.1 - 0.0006 19.7 0.0 0.19 11.5 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase AXE1 PF05448.12 AAZ36938.1 - 0.1 11.3 0.1 0.17 10.5 0.1 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DLH PF01738.18 AAZ36938.1 - 0.14 11.7 0.0 3.7 7.0 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Chlorophyllase PF07224.11 AAZ36938.1 - 0.14 11.1 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase RNA_pol_A_bac PF01000.26 AAZ36939.1 - 7e-26 90.8 0.1 1.4e-25 89.8 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_A_CTD PF03118.15 AAZ36939.1 - 2.8e-24 84.7 0.2 5.1e-24 83.8 0.2 1.5 1 0 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain RNA_pol_L PF01193.24 AAZ36939.1 - 1.8e-23 81.7 0.0 4.1e-23 80.6 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L_2 PF13656.6 AAZ36939.1 - 0.00088 19.0 0.0 1.2 8.9 0.0 2.6 2 0 0 2 2 2 2 RNA polymerase Rpb3/Rpb11 dimerisation domain NolB PF17398.2 AAZ36941.1 - 0.022 15.2 0.1 0.028 14.8 0.1 1.2 1 0 0 1 1 1 0 Nodulation protein NolB FlhE PF06366.13 AAZ36942.1 - 1.7e-11 44.0 0.2 2.8e-11 43.3 0.1 1.4 2 0 0 2 2 2 1 Flagellar protein FlhE N6_Mtase PF02384.16 AAZ36943.1 - 1.5e-57 195.2 0.0 3e-57 194.3 0.0 1.4 1 0 0 1 1 1 1 N-6 DNA Methylase HsdM_N PF12161.8 AAZ36943.1 - 3.8e-22 79.4 0.6 3.8e-22 79.4 0.6 2.4 3 1 0 3 3 3 1 HsdM N-terminal domain UPF0020 PF01170.18 AAZ36943.1 - 2e-05 24.4 0.0 0.00011 21.9 0.0 2.2 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 PIN_4 PF13638.6 AAZ36943.1 - 0.021 15.1 0.0 0.074 13.3 0.0 1.9 1 0 0 1 1 1 0 PIN domain Flavodoxin_1 PF00258.25 AAZ36943.1 - 0.091 13.0 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin AviRa PF11599.8 AAZ36943.1 - 0.14 11.6 0.0 0.49 9.8 0.0 1.9 2 0 0 2 2 2 0 RRNA methyltransferase AviRa PSII_BNR PF14870.6 AAZ36944.1 - 2.3e-30 105.9 4.9 5.6e-18 65.2 0.6 4.0 1 1 2 3 3 3 3 Photosynthesis system II assembly factor YCF48 Sortilin-Vps10 PF15902.5 AAZ36944.1 - 2.5e-15 56.2 0.0 8.5e-07 28.1 0.0 3.3 1 1 1 3 3 3 3 Sortilin, neurotensin receptor 3, BNR PF02012.20 AAZ36944.1 - 3.1e-12 44.5 20.4 0.048 13.6 0.3 6.5 6 0 0 6 6 6 4 BNR/Asp-box repeat BNR_2 PF13088.6 AAZ36944.1 - 9.7e-07 28.4 4.0 0.028 13.7 0.2 4.8 2 2 1 3 3 3 3 BNR repeat-like domain DUF4185 PF13810.6 AAZ36944.1 - 4.5e-06 26.1 1.6 3.9 6.6 0.0 5.1 2 1 3 5 5 5 3 Domain of unknown function (DUF4185) BNR_6 PF15899.5 AAZ36944.1 - 1.1e-05 25.0 7.4 0.1 12.7 0.1 4.9 4 0 0 4 4 4 2 BNR-Asp box repeat PapC_C PF13953.6 AAZ36944.1 - 0.13 12.1 5.3 0.84 9.5 0.1 3.8 4 0 0 4 4 4 0 PapC C-terminal domain DUF1329 PF07044.11 AAZ36946.1 - 2.3e-157 524.0 4.3 2.6e-157 523.8 4.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1329) LolA_like PF17131.4 AAZ36946.1 - 1.5e-08 34.6 0.1 6.2e-07 29.3 0.1 2.3 1 1 0 1 1 1 1 Outer membrane lipoprotein-sorting protein DUF3335 PF11814.8 AAZ36947.1 - 5.3e-86 287.3 0.0 7.2e-86 286.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase_C39 like family Acetyltransf_1 PF00583.25 AAZ36947.1 - 9.9e-17 61.3 0.1 2.4e-16 60.0 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AAZ36947.1 - 3.7e-12 46.3 0.0 7.1e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAZ36947.1 - 1.1e-09 38.6 0.6 3.4e-09 37.0 0.2 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAZ36947.1 - 9.5e-07 28.7 0.5 8.1e-06 25.7 0.1 2.3 2 0 0 2 2 2 1 FR47-like protein Peptidase_C70 PF12385.8 AAZ36947.1 - 0.0027 17.7 0.0 1.2 9.1 0.0 2.2 2 0 0 2 2 2 2 Papain-like cysteine protease AvrRpt2 Acetyltransf_8 PF13523.6 AAZ36947.1 - 0.0052 16.5 0.0 0.016 14.9 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Peptidase_C39_2 PF13529.6 AAZ36947.1 - 0.0056 17.2 0.0 0.18 12.4 0.0 2.2 2 0 0 2 2 2 1 Peptidase_C39 like family Acetyltransf_3 PF13302.7 AAZ36947.1 - 0.054 14.2 0.0 0.095 13.4 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Peptidase_C39 PF03412.15 AAZ36947.1 - 0.063 13.1 0.1 4.7 7.0 0.0 2.7 2 1 0 2 2 2 0 Peptidase C39 family DUF4434 PF14488.6 AAZ36948.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) DUF2590 PF10761.9 AAZ36949.1 - 6.9e-39 132.0 0.7 7.6e-39 131.9 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2590) BRX PF08381.11 AAZ36949.1 - 0.13 11.6 0.0 1.8 8.0 0.1 2.1 2 0 0 2 2 2 0 Transcription factor regulating root and shoot growth via Pin3 TetR PF13972.6 AAZ36950.1 - 3.2e-44 150.1 1.0 4.9e-44 149.5 1.0 1.3 1 0 0 1 1 1 1 Bacterial transcriptional repressor TetR_N PF00440.23 AAZ36950.1 - 7.5e-11 41.6 0.0 1.6e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_20 PF12840.7 AAZ36950.1 - 0.037 14.1 0.1 1.8 8.6 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain TetR_C_9 PF14514.6 AAZ36950.1 - 0.078 13.1 0.8 0.12 12.6 0.8 1.4 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain HrcA_DNA-bdg PF03444.15 AAZ36950.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding HTH_5 PF01022.20 AAZ36950.1 - 0.16 11.8 0.0 0.64 9.9 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family OprB PF04966.12 AAZ36951.1 - 8.4e-113 377.6 8.3 1e-112 377.3 8.3 1.1 1 0 0 1 1 1 1 Carbohydrate-selective porin, OprB family N_methyl PF07963.12 AAZ36952.1 - 3.1e-06 26.5 0.7 5.2e-06 25.8 0.7 1.4 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif PilW PF16074.5 AAZ36952.1 - 1.1e-05 25.5 0.4 2e-05 24.6 0.1 1.5 2 0 0 2 2 2 1 Type IV Pilus-assembly protein W MFS_1 PF07690.16 AAZ36953.1 - 8.8e-14 51.2 56.9 2.3e-08 33.4 31.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Acatn PF13000.7 AAZ36953.1 - 4.2e-09 35.5 11.4 1.7e-06 26.9 11.4 2.4 1 1 0 1 1 1 1 Acetyl-coenzyme A transporter 1 DUF2389 PF09493.10 AAZ36954.1 - 7.8e-21 74.5 1.4 8.9e-21 74.3 1.4 1.1 1 0 0 1 1 1 1 Tryptophan-rich protein (DUF2389) Aldedh PF00171.22 AAZ36955.1 - 0.059 11.9 0.1 0.059 11.9 0.1 1.0 1 0 0 1 1 1 0 Aldehyde dehydrogenase family ArfA PF03889.13 AAZ36955.1 - 0.14 11.7 0.1 0.21 11.1 0.1 1.3 1 0 0 1 1 1 0 Alternative ribosome-rescue factor A Response_reg PF00072.24 AAZ36956.1 - 3.9e-29 101.1 0.0 6e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAZ36956.1 - 3.8e-27 94.2 1.7 4.7e-27 93.9 0.0 2.0 3 0 0 3 3 3 1 Transcriptional regulatory protein, C terminal MFS_1 PF07690.16 AAZ36957.1 - 1e-57 195.7 36.6 1e-57 195.7 36.6 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily AsnC_trans_reg PF01037.21 AAZ36958.1 - 2.3e-20 72.3 0.0 3.4e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 AAZ36958.1 - 1.9e-19 69.0 0.1 2.8e-19 68.4 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 AAZ36958.1 - 3.4e-18 65.2 0.3 5.7e-18 64.5 0.3 1.4 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_11 PF08279.12 AAZ36958.1 - 2.4e-05 24.2 0.1 4.5e-05 23.3 0.1 1.5 1 1 0 1 1 1 1 HTH domain HTH_Crp_2 PF13545.6 AAZ36958.1 - 5.4e-05 23.1 0.1 9.7e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain MarR_2 PF12802.7 AAZ36958.1 - 0.00027 20.8 0.3 0.0004 20.2 0.3 1.3 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 AAZ36958.1 - 0.00031 20.7 0.0 0.0005 20.1 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain MarR PF01047.22 AAZ36958.1 - 0.00098 19.0 0.2 0.0018 18.2 0.2 1.4 1 0 0 1 1 1 1 MarR family HTH_5 PF01022.20 AAZ36958.1 - 0.0011 18.8 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family TrmB PF01978.19 AAZ36958.1 - 0.0027 17.6 0.0 0.0045 16.8 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.10 AAZ36958.1 - 0.0031 17.3 0.1 0.0072 16.1 0.0 1.6 2 0 0 2 2 2 1 IclR helix-turn-helix domain Rrf2 PF02082.20 AAZ36958.1 - 0.0037 17.6 0.0 0.0069 16.7 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulator HTH_1 PF00126.27 AAZ36958.1 - 0.0042 17.0 0.1 0.0069 16.3 0.1 1.5 1 1 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family Phage_rep_O PF04492.13 AAZ36958.1 - 0.026 15.1 0.0 0.039 14.5 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage replication protein O Replic_Relax PF13814.6 AAZ36958.1 - 0.028 14.5 0.1 0.035 14.2 0.1 1.2 1 0 0 1 1 1 0 Replication-relaxation Sigma70_r4_2 PF08281.12 AAZ36958.1 - 0.031 14.0 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.6 AAZ36958.1 - 0.048 13.1 0.0 0.093 12.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 LexA_DNA_bind PF01726.16 AAZ36958.1 - 0.05 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 LexA DNA binding domain HTH_39 PF14090.6 AAZ36958.1 - 0.086 12.6 0.1 0.22 11.3 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 AAZ36958.1 - 0.13 12.1 0.3 0.27 11.1 0.2 1.6 1 1 0 1 1 1 0 Homeodomain-like domain PhnH PF05845.12 AAZ36959.1 - 3.4e-57 193.3 0.1 3.8e-57 193.1 0.1 1.0 1 0 0 1 1 1 1 Bacterial phosphonate metabolism protein (PhnH) DUF1989 PF09347.10 AAZ36960.1 - 2.7e-48 163.8 0.0 4.4e-48 163.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) ABC_tran PF00005.27 AAZ36960.1 - 1.2e-25 90.6 0.0 2.8e-25 89.4 0.0 1.6 2 0 0 2 2 1 1 ABC transporter AAA_16 PF13191.6 AAZ36960.1 - 0.00045 20.6 0.1 0.00082 19.8 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AAZ36960.1 - 0.0066 16.4 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_33 PF13671.6 AAZ36960.1 - 0.017 15.2 0.0 0.038 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AAZ36960.1 - 0.028 14.1 0.0 0.06 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 AAZ36960.1 - 0.03 13.9 0.0 0.065 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AAZ36960.1 - 0.033 14.5 0.0 0.067 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 AAZ36960.1 - 0.16 11.8 0.0 0.34 10.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 AAZ36960.1 - 0.16 11.2 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.23 AAZ36960.1 - 0.19 11.8 0.0 0.44 10.7 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase T2SSM_b PF10741.9 AAZ36962.1 - 2e-31 108.0 0.0 2.8e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein M subtype b T2SSM PF04612.12 AAZ36962.1 - 2e-05 24.7 0.9 3.6e-05 23.9 0.9 1.4 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein M Rootletin PF15035.6 AAZ36962.1 - 0.00059 19.9 0.1 0.0009 19.3 0.1 1.2 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion DivIC PF04977.15 AAZ36962.1 - 0.0028 17.4 0.1 0.0051 16.6 0.1 1.4 1 0 0 1 1 1 1 Septum formation initiator DMRL_synthase PF00885.19 AAZ36963.1 - 2e-34 118.4 0.1 2.6e-34 118.0 0.1 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase DUF5542 PF17696.1 AAZ36963.1 - 0.47 10.6 2.8 8.5 6.6 0.3 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5542) MreC PF04085.14 AAZ36964.1 - 3.5e-35 121.1 0.0 5.7e-35 120.4 0.0 1.3 1 0 0 1 1 1 1 rod shape-determining protein MreC Alpha-amylase PF00128.24 AAZ36965.1 - 9.3e-17 61.6 0.1 9.1e-14 51.7 0.1 2.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain CBM_48 PF02922.18 AAZ36965.1 - 4.5e-16 59.0 0.0 1.3e-15 57.5 0.0 1.8 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) GHL5 PF14872.6 AAZ36965.1 - 0.013 13.6 0.0 0.019 13.0 0.0 1.1 1 0 0 1 1 1 0 Hypothetical glycoside hydrolase 5 FKBP_C PF00254.28 AAZ36966.1 - 8.5e-34 115.8 0.0 1.1e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPP_enzyme_N PF02776.18 AAZ36967.1 - 8.6e-45 152.4 2.5 1.4e-42 145.2 0.1 3.4 2 1 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 AAZ36967.1 - 1.2e-40 138.8 0.1 1.2e-37 129.1 0.0 3.4 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 AAZ36967.1 - 2.1e-30 105.2 0.0 7.5e-30 103.5 0.0 2.0 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 AAZ36967.1 - 0.028 14.2 0.0 0.06 13.1 0.0 1.5 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg NTP_transf_3 PF12804.7 AAZ36967.1 - 0.1 13.0 4.5 4.5 7.6 0.1 3.3 3 1 0 3 3 3 0 MobA-like NTP transferase domain HAD PF12710.7 AAZ36968.1 - 1.5e-08 35.3 0.0 2.6e-08 34.5 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAZ36968.1 - 2.6e-06 27.9 0.0 3.4e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 AAZ36968.1 - 0.004 16.6 0.0 0.013 14.9 0.0 1.8 2 0 0 2 2 2 1 Putative Phosphatase Hydrolase_3 PF08282.12 AAZ36968.1 - 0.14 11.8 0.0 0.47 10.2 0.0 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase ATP-synt_ab PF00006.25 AAZ36969.1 - 7.3e-76 254.5 0.0 1e-75 254.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain T3SS_ATPase_C PF18269.1 AAZ36969.1 - 1.6e-24 85.5 0.1 2.8e-24 84.7 0.1 1.4 1 0 0 1 1 1 1 T3SS EscN ATPase C-terminal domain ATP-synt_ab_N PF02874.23 AAZ36969.1 - 2.1e-06 28.2 0.2 4.2e-06 27.2 0.2 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ABC_tran PF00005.27 AAZ36969.1 - 5.5e-05 23.7 0.0 0.00011 22.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 AAZ36969.1 - 0.0034 17.8 0.9 0.0034 17.8 0.9 2.5 2 1 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 AAZ36969.1 - 0.0035 17.4 0.1 0.012 15.7 0.0 1.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 AAZ36969.1 - 0.01 16.1 0.0 0.027 14.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 AAZ36969.1 - 0.013 15.4 0.1 0.023 14.6 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase MeaB PF03308.16 AAZ36969.1 - 0.016 14.2 0.7 0.12 11.3 0.1 2.1 1 1 1 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATPase_2 PF01637.18 AAZ36969.1 - 0.018 15.0 0.0 0.026 14.4 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 AAZ36969.1 - 0.068 13.6 0.0 0.25 11.7 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 AAZ36969.1 - 0.073 12.2 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.15 AAZ36969.1 - 0.074 13.0 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 NTPase NACHT PF05729.12 AAZ36969.1 - 0.11 12.5 0.0 0.67 9.9 0.0 2.3 3 0 0 3 3 3 0 NACHT domain AAA_24 PF13479.6 AAZ36969.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF772 PF05598.11 AAZ36970.1 - 9.1e-20 70.5 0.0 1.5e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Transposase domain (DUF772) DDE_Tnp_1 PF01609.21 AAZ36970.1 - 8.6e-13 48.4 0.4 2.6e-12 46.8 0.3 1.7 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 AAZ36970.1 - 0.077 13.0 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain GATase_6 PF13522.6 AAZ36971.1 - 6.2e-20 71.8 0.1 1.4e-19 70.6 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.6 AAZ36971.1 - 6.5e-19 68.1 0.0 1.1e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 AAZ36971.1 - 0.00013 21.0 0.0 0.00022 20.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II N_methyl PF07963.12 AAZ36972.1 - 1.8e-07 30.4 0.9 2.8e-07 29.8 0.9 1.3 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif OTCace_N PF02729.21 AAZ36973.1 - 1.8e-40 138.3 0.1 3e-40 137.7 0.1 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 AAZ36973.1 - 1.4e-23 83.7 0.0 4.1e-23 82.2 0.0 1.8 2 1 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain PTPS PF01242.19 AAZ36974.1 - 9.9e-38 128.9 0.0 1.1e-37 128.7 0.0 1.0 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase T2SSE PF00437.20 AAZ36975.1 - 5.9e-90 301.0 1.3 8.1e-90 300.6 1.3 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein T2SSE_N PF05157.15 AAZ36975.1 - 1e-16 61.1 0.0 2.6e-16 59.8 0.0 1.7 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein E, N-terminal domain AAA_30 PF13604.6 AAZ36975.1 - 0.0017 18.1 0.5 0.0078 15.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 AAZ36975.1 - 0.003 17.9 0.6 0.0082 16.4 0.1 2.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AAZ36975.1 - 0.019 15.4 0.4 0.05 14.0 0.1 1.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.6 AAZ36975.1 - 0.045 13.8 0.0 0.092 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AAZ36975.1 - 0.071 12.9 0.1 0.24 11.2 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain PhoH PF02562.16 AAZ36975.1 - 0.093 12.2 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_7 PF12775.7 AAZ36975.1 - 0.13 11.7 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Phosphodiest PF01663.22 AAZ36976.1 - 5.2e-09 36.2 0.0 7.4e-06 25.8 0.0 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Acetyltransf_1 PF00583.25 AAZ36977.1 - 3.9e-08 33.5 0.0 4.8e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AAZ36977.1 - 8.7e-05 22.5 0.0 0.00017 21.5 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAZ36977.1 - 0.00027 20.9 0.0 0.00061 19.7 0.0 1.7 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 AAZ36977.1 - 0.00074 19.9 0.0 0.0017 18.7 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 AAZ36977.1 - 0.00075 19.2 0.0 0.0011 18.7 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AAZ36977.1 - 0.018 15.7 0.0 0.021 15.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Peptidase_A8 PF01252.18 AAZ36979.1 - 4.7e-40 137.1 10.2 5.3e-40 136.9 10.2 1.0 1 0 0 1 1 1 1 Signal peptidase (SPase) II ThrE PF06738.12 AAZ36979.1 - 3.2 7.0 8.9 45 3.3 8.6 2.0 1 1 0 1 1 1 0 Putative threonine/serine exporter DUF983 PF06170.12 AAZ36979.1 - 3.4 8.1 6.9 7.6 7.0 4.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF983) MFS_1 PF07690.16 AAZ36980.1 - 2.1e-36 125.6 52.2 2.1e-36 125.6 52.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Aldedh PF00171.22 AAZ36981.1 - 8.1e-47 159.8 0.0 1.2e-46 159.2 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HATPase_c PF02518.26 AAZ36982.1 - 4.3e-16 59.4 0.0 9.5e-16 58.3 0.0 1.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 2CSK_N PF08521.10 AAZ36982.1 - 1.6e-11 44.5 0.2 3.4e-11 43.4 0.2 1.6 1 0 0 1 1 1 1 Two-component sensor kinase N-terminal HisKA PF00512.25 AAZ36982.1 - 4.1e-10 39.6 6.4 4.3e-10 39.5 2.9 2.5 1 1 1 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 AAZ36982.1 - 4.3e-06 26.7 0.2 0.00012 22.1 0.0 2.5 3 0 0 3 3 3 1 Histidine kinase-like ATPase domain HAMP PF00672.25 AAZ36982.1 - 0.0025 18.2 0.1 0.0025 18.2 0.1 3.2 3 0 0 3 3 3 1 HAMP domain HATPase_c_5 PF14501.6 AAZ36982.1 - 0.0056 16.6 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 GHKL domain Sensor PF13796.6 AAZ36982.1 - 0.0062 16.6 0.5 0.016 15.3 0.5 1.6 1 0 0 1 1 1 1 Putative sensor HATPase_c_3 PF13589.6 AAZ36982.1 - 0.018 14.8 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CbiC PF02570.15 AAZ36983.1 - 1e-71 240.7 0.1 1.1e-71 240.5 0.1 1.0 1 0 0 1 1 1 1 Precorrin-8X methylmutase ABC_membrane PF00664.23 AAZ36984.1 - 4e-57 194.0 12.1 5.5e-57 193.5 12.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 AAZ36984.1 - 1.8e-33 115.9 0.0 3.3e-33 115.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter Peptidase_C39 PF03412.15 AAZ36984.1 - 3.1e-21 75.5 0.0 7.6e-21 74.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase C39 family SMC_N PF02463.19 AAZ36984.1 - 1e-06 28.4 0.0 5.6e-05 22.7 0.0 2.1 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AAZ36984.1 - 0.00078 19.9 0.0 0.0024 18.3 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AAZ36984.1 - 0.0094 16.2 0.1 0.045 14.0 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AAZ36984.1 - 0.011 16.2 0.0 0.038 14.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 AAZ36984.1 - 0.015 15.0 0.1 0.044 13.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AAZ36984.1 - 0.021 14.6 0.0 0.053 13.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_ATPase PF09818.9 AAZ36984.1 - 0.029 13.2 0.4 0.43 9.3 0.0 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class DUF87 PF01935.17 AAZ36984.1 - 0.032 14.3 0.0 0.078 13.1 0.0 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain MeaB PF03308.16 AAZ36984.1 - 0.044 12.8 0.0 0.072 12.1 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PRK PF00485.18 AAZ36984.1 - 0.055 13.2 0.1 0.15 11.8 0.1 1.7 1 1 1 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_21 PF13304.6 AAZ36984.1 - 0.14 11.9 0.0 0.51 10.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system NAD_binding_9 PF13454.6 AAZ36985.1 - 2.5e-29 102.3 0.0 4.7e-29 101.4 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding cNMP_binding PF00027.29 AAZ36986.1 - 7e-17 61.3 0.1 1.9e-16 59.9 0.0 1.7 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain HTH_Crp_2 PF13545.6 AAZ36986.1 - 3.5e-15 55.7 0.2 6.3e-15 54.9 0.2 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Crp PF00325.20 AAZ36986.1 - 4.3e-14 51.9 0.0 9.5e-14 50.8 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, crp family HTH_Tnp_ISL3 PF13542.6 AAZ36986.1 - 0.073 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 BPD_transp_1 PF00528.22 AAZ36987.1 - 1.1e-28 100.2 7.5 1.1e-28 100.2 7.5 1.8 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 AAZ36987.1 - 2.6e-06 27.3 0.1 2.6e-06 27.3 0.1 3.0 3 0 0 3 3 3 1 N-terminal TM domain of oligopeptide transport permease C DUF4658 PF15555.6 AAZ36987.1 - 0.015 15.4 0.5 0.031 14.4 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) TerC PF03741.16 AAZ36987.1 - 0.11 12.2 0.2 0.11 12.2 0.2 2.4 2 1 1 3 3 3 0 Integral membrane protein TerC family Channel_Tsx PF03502.13 AAZ36988.1 - 5.8e-67 226.0 12.4 6.8e-67 225.8 12.4 1.0 1 0 0 1 1 1 1 Nucleoside-specific channel-forming protein, Tsx ADH_N PF08240.12 AAZ36990.1 - 4.1e-25 87.8 2.5 6.6e-25 87.1 2.5 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AAZ36990.1 - 1.4e-09 38.0 0.0 2.3e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 AAZ36990.1 - 4.6e-07 29.5 0.0 8.1e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus FAD_binding_3 PF01494.19 AAZ36990.1 - 0.0032 16.8 0.0 0.0048 16.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain MetW PF07021.12 AAZ36990.1 - 0.014 15.0 0.1 0.023 14.3 0.1 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW ADH_zinc_N_2 PF13602.6 AAZ36990.1 - 0.027 15.5 0.1 0.11 13.5 0.0 2.1 1 1 2 3 3 3 0 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 AAZ36990.1 - 0.034 13.4 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UvrA_inter PF17760.1 AAZ36991.1 - 5.7e-38 129.4 0.1 1.4e-37 128.1 0.1 1.7 1 0 0 1 1 1 1 UvrA interaction domain UvrA_DNA-bind PF17755.1 AAZ36991.1 - 3.8e-33 114.1 0.0 7e-32 110.0 0.0 2.6 2 0 0 2 2 2 1 UvrA DNA-binding domain ABC_tran PF00005.27 AAZ36991.1 - 1.5e-21 77.4 0.0 8.9e-05 23.0 0.0 4.4 4 0 0 4 4 4 4 ABC transporter SMC_N PF02463.19 AAZ36991.1 - 2e-10 40.5 0.0 0.18 11.2 0.0 4.1 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AAZ36991.1 - 6.5e-08 33.1 0.2 0.032 14.6 0.0 3.6 3 1 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 AAZ36991.1 - 2e-07 30.6 1.2 0.0031 17.2 0.4 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain BCA_ABC_TP_C PF12399.8 AAZ36991.1 - 1.7e-06 27.8 0.7 0.0087 16.0 0.0 2.6 2 0 0 2 2 2 2 Branched-chain amino acid ATP-binding cassette transporter AAA_23 PF13476.6 AAZ36991.1 - 3.1e-05 24.6 3.2 0.023 15.2 0.1 2.5 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 AAZ36991.1 - 4.8e-05 23.3 0.2 0.31 10.9 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 AAZ36991.1 - 5.5e-05 23.5 0.4 0.8 10.0 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 AAZ36991.1 - 6.9e-05 23.0 0.1 0.27 11.4 0.0 3.2 4 0 0 4 4 2 2 AAA domain AAA_18 PF13238.6 AAZ36991.1 - 0.0007 20.1 0.9 2.3 8.8 0.0 3.1 3 0 0 3 3 2 2 AAA domain DnaJ_CXXCXGXG PF00684.19 AAZ36991.1 - 0.00097 19.5 2.7 1 9.7 0.2 3.4 3 0 0 3 3 3 1 DnaJ central domain DUF2075 PF09848.9 AAZ36991.1 - 0.0015 17.9 0.1 1.4 8.0 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 AAZ36991.1 - 0.0018 18.1 0.0 0.094 12.4 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase APS_kinase PF01583.20 AAZ36991.1 - 0.0034 17.3 0.7 0.89 9.4 0.0 3.0 3 0 0 3 3 2 1 Adenylylsulphate kinase AAA_24 PF13479.6 AAZ36991.1 - 0.0043 16.8 0.1 1.6 8.4 0.0 3.3 3 0 0 3 3 3 1 AAA domain cobW PF02492.19 AAZ36991.1 - 0.0061 16.2 2.1 0.33 10.5 0.8 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 AAZ36991.1 - 0.0068 16.0 1.4 0.25 10.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 AAZ36991.1 - 0.0084 15.8 0.3 9.9 5.8 0.1 3.4 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 AAZ36991.1 - 0.012 15.6 0.0 8.8 6.4 0.0 3.4 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 AAZ36991.1 - 0.02 14.0 0.4 4.1 6.4 0.1 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein NACHT PF05729.12 AAZ36991.1 - 0.022 14.7 0.1 4.3 7.2 0.1 2.5 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.23 AAZ36991.1 - 0.029 14.4 0.3 2.5 8.2 0.1 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 AAZ36991.1 - 0.031 14.2 0.6 2 8.3 0.0 3.4 3 0 0 3 3 3 0 NTPase AAA_21 PF13304.6 AAZ36991.1 - 0.034 14.0 8.5 0.42 10.4 0.0 3.9 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system Zn-ribbon_8 PF09723.10 AAZ36991.1 - 0.039 14.1 8.8 0.84 9.8 0.3 3.6 3 0 0 3 3 3 0 Zinc ribbon domain ATPase PF06745.13 AAZ36991.1 - 0.059 12.7 0.0 5.4 6.3 0.0 2.4 2 0 0 2 2 2 0 KaiC AAA_7 PF12775.7 AAZ36991.1 - 0.083 12.4 0.1 15 5.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_28 PF13521.6 AAZ36991.1 - 0.13 12.5 0.2 22 5.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 AAZ36991.1 - 0.14 12.0 0.1 6.6 6.6 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Anti-TRAP PF15777.5 AAZ36991.1 - 0.14 12.1 4.0 47 4.1 0.0 3.9 3 1 0 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein NB-ARC PF00931.22 AAZ36991.1 - 0.15 11.2 0.0 58 2.7 0.0 3.1 3 0 0 3 3 3 0 NB-ARC domain CobU PF02283.16 AAZ36992.1 - 1.5e-59 200.4 0.0 1.7e-59 200.2 0.0 1.0 1 0 0 1 1 1 1 Cobinamide kinase / cobinamide phosphate guanyltransferase DnaJ_C PF01556.18 AAZ36994.1 - 7.4e-44 149.4 0.0 9.3e-44 149.1 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 AAZ36994.1 - 5.9e-26 90.4 1.7 9.3e-26 89.7 1.7 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 AAZ36994.1 - 7.1e-15 55.1 15.5 1.2e-14 54.4 15.5 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 AAZ36994.1 - 0.00011 22.1 15.8 0.0043 17.0 3.7 3.1 1 1 2 3 3 3 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 AAZ36994.1 - 0.037 14.0 6.6 0.075 13.1 0.2 2.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA SCP_3 PF17844.1 AAZ36994.1 - 0.16 11.7 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial SCP ortholog Cytochrome_CBB3 PF13442.6 AAZ36994.1 - 0.22 11.9 4.7 6.9 7.1 0.1 2.8 1 1 1 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III Cytochrome_C7 PF14522.6 AAZ36994.1 - 2.6 8.1 8.9 11 6.1 7.6 2.6 2 1 0 2 2 2 0 Cytochrome c7 and related cytochrome c zinc-ribbons_6 PF07191.12 AAZ36994.1 - 2.8 8.0 5.4 9.6 6.3 5.5 1.8 1 1 0 1 1 1 0 zinc-ribbons Lar_restr_allev PF14354.6 AAZ36994.1 - 9.7 6.7 10.0 31 5.0 0.2 3.3 2 1 1 3 3 3 0 Restriction alleviation protein Lar SecY PF00344.20 AAZ36995.1 - 2e-114 382.0 16.3 2.9e-114 381.4 16.3 1.2 1 0 0 1 1 1 1 SecY translocase DUF3054 PF11255.8 AAZ36995.1 - 5.3 7.6 11.1 0.67 10.5 1.9 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3054) Hexapep PF00132.24 AAZ36996.1 - 1.1e-12 47.1 5.9 0.00011 21.8 0.2 3.7 2 1 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) PglD_N PF17836.1 AAZ36996.1 - 8.6e-09 35.9 0.0 2e-08 34.7 0.0 1.6 2 0 0 2 2 2 1 PglD N-terminal domain Hexapep_2 PF14602.6 AAZ36996.1 - 9.8e-06 25.2 6.3 0.039 13.7 0.4 3.7 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase GFO_IDH_MocA PF01408.22 AAZ36996.1 - 0.17 12.7 0.0 0.31 11.9 0.0 1.5 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold NRho PF16733.5 AAZ36997.1 - 3.3e-29 100.7 0.2 7.4e-29 99.6 0.2 1.6 1 0 0 1 1 1 1 Rhomboid N-terminal domain Rhomboid PF01694.22 AAZ36997.1 - 6.4e-27 94.4 17.6 1e-26 93.7 17.6 1.3 1 0 0 1 1 1 1 Rhomboid family Tom6 PF17112.5 AAZ36997.1 - 0.14 11.7 0.1 0.48 10.0 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom6, fungal PTS_IIB PF02302.17 AAZ36998.1 - 4e-30 104.4 0.4 1.1e-18 67.6 0.4 2.6 2 1 0 2 2 2 2 PTS system, Lactose/Cellobiose specific IIB subunit PTS_EIIC PF02378.18 AAZ36998.1 - 3.7e-20 72.2 30.3 3.7e-20 72.2 30.3 3.1 2 1 1 3 3 3 1 Phosphotransferase system, EIIC DUF5455 PF17537.2 AAZ36998.1 - 1.4 9.4 6.1 0.57 10.6 1.2 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5455) LysR_substrate PF03466.20 AAZ36999.1 - 6.7e-36 123.6 0.8 1.2e-35 122.8 0.8 1.4 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ36999.1 - 4.2e-20 71.5 0.7 9.3e-20 70.3 0.7 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_Tnp_ISL3 PF13542.6 AAZ36999.1 - 0.099 12.1 0.1 0.33 10.4 0.1 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 RNA_pol_Rpb2_6 PF00562.28 AAZ37001.1 - 1.4e-161 538.0 0.3 2.3e-160 533.9 0.4 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 AAZ37001.1 - 3.7e-42 144.2 0.0 8.1e-42 143.0 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 AAZ37001.1 - 4.8e-30 103.5 0.0 1.6e-29 101.9 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 AAZ37001.1 - 2.3e-27 95.2 0.0 4.9e-27 94.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 AAZ37001.1 - 7.1e-25 87.7 0.0 4.2e-15 55.9 0.0 2.9 3 0 0 3 3 3 2 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_45 PF10385.9 AAZ37001.1 - 1e-18 67.3 2.2 7.2e-18 64.6 1.0 3.1 3 0 0 3 3 3 1 RNA polymerase beta subunit external 1 domain 7TMR-HDED PF07697.11 AAZ37001.1 - 0.25 11.4 5.7 0.08 13.0 0.4 2.6 3 0 0 3 3 3 0 7TM-HD extracellular DHDPS PF00701.22 AAZ37002.1 - 1.8e-106 355.1 0.0 2e-106 354.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PA PF02225.22 AAZ37002.1 - 0.0092 16.0 0.1 0.018 15.0 0.1 1.5 1 0 0 1 1 1 1 PA domain DHO_dh PF01180.21 AAZ37002.1 - 0.033 13.4 0.1 0.051 12.8 0.1 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Formyl_trans_N PF00551.19 AAZ37003.1 - 2.2e-46 157.9 0.0 2.9e-46 157.5 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 AAZ37003.1 - 6.2e-27 93.8 0.0 1e-26 93.1 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain ATP_bind_3 PF01171.20 AAZ37004.1 - 1.5e-14 54.2 0.0 2.3e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 PP-loop family NAD_synthase PF02540.17 AAZ37004.1 - 0.01 14.9 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 NAD synthase PAPS_reduct PF01507.19 AAZ37004.1 - 0.099 12.7 0.0 1.1 9.3 0.0 2.1 1 1 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Lyase_1 PF00206.20 AAZ37005.1 - 2.3e-64 217.8 0.0 3.1e-64 217.3 0.0 1.1 1 0 0 1 1 1 1 Lyase ASL_C PF08328.11 AAZ37005.1 - 5.6e-52 174.7 0.0 2.7e-51 172.5 0.0 2.0 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminal FliG_M PF14841.6 AAZ37005.1 - 0.1 12.8 0.3 0.27 11.5 0.3 1.6 1 0 0 1 1 1 0 FliG middle domain OEP PF02321.18 AAZ37006.1 - 2.2e-41 141.8 25.7 2.3e-21 76.5 4.3 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein SPOUT_MTase PF02590.17 AAZ37006.1 - 0.081 12.9 0.9 0.14 12.1 0.1 1.7 2 0 0 2 2 2 0 Predicted SPOUT methyltransferase OprB PF04966.12 AAZ37006.1 - 0.098 12.1 2.3 0.064 12.6 0.3 1.6 2 0 0 2 2 2 0 Carbohydrate-selective porin, OprB family Response_reg PF00072.24 AAZ37007.1 - 8e-25 87.2 0.9 9e-25 87.0 0.9 1.0 1 0 0 1 1 1 1 Response regulator receiver domain FleQ PF06490.11 AAZ37007.1 - 0.0013 19.1 0.1 0.0017 18.7 0.1 1.1 1 0 0 1 1 1 1 Flagellar regulatory protein FleQ DUF3298 PF11738.8 AAZ37008.1 - 2.8e-06 28.2 0.0 4.6e-06 27.6 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3298) PdaC PF13739.6 AAZ37008.1 - 0.017 16.1 0.0 0.13 13.2 0.0 2.3 2 0 0 2 2 2 0 Deacetylase PdaC PAW PF04721.17 AAZ37008.1 - 0.13 12.0 0.2 0.18 11.5 0.2 1.2 1 0 0 1 1 1 0 PNGase C-terminal domain, mannose-binding module PAW T6SS_HCP PF05638.12 AAZ37009.1 - 9.5e-36 123.0 0.0 1.2e-35 122.7 0.0 1.1 1 0 0 1 1 1 1 Type VI secretion system effector, Hcp CsrA PF02599.16 AAZ37010.1 - 4.9e-17 61.6 0.2 6.5e-17 61.2 0.2 1.2 1 0 0 1 1 1 1 Global regulator protein family Acetyltransf_1 PF00583.25 AAZ37011.1 - 5.3e-19 68.6 0.0 7.1e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAZ37011.1 - 1.9e-11 44.2 0.0 2.9e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAZ37011.1 - 1.1e-10 41.6 0.0 1.7e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAZ37011.1 - 0.0073 16.3 0.0 0.025 14.5 0.0 1.9 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 AAZ37011.1 - 0.011 16.4 0.0 0.015 16.0 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 AAZ37011.1 - 0.017 14.9 0.0 0.026 14.2 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_13 PF13880.6 AAZ37011.1 - 0.025 14.5 0.0 0.047 13.7 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_8 PF13523.6 AAZ37011.1 - 0.081 12.6 0.0 0.32 10.7 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AAZ37011.1 - 0.1 12.7 0.0 0.93 9.6 0.0 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain adh_short_C2 PF13561.6 AAZ37012.1 - 1.4e-60 204.8 2.1 1.6e-60 204.6 2.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAZ37012.1 - 2e-54 184.1 1.1 2.4e-54 183.8 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAZ37012.1 - 7.1e-16 58.6 0.8 1e-15 58.2 0.8 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 AAZ37012.1 - 0.059 12.7 0.0 1.6 8.0 0.0 2.1 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 AAZ37012.1 - 0.06 12.8 0.2 0.13 11.7 0.2 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GGDEF PF00990.21 AAZ37013.1 - 5.6e-46 156.2 0.1 7.9e-46 155.7 0.1 1.2 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain GGDEF_2 PF17853.1 AAZ37013.1 - 0.093 13.0 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 GGDEF-like domain adh_short PF00106.25 AAZ37016.1 - 1e-43 149.1 0.0 1.2e-43 148.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAZ37016.1 - 2.8e-28 99.1 0.0 4.2e-28 98.5 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAZ37016.1 - 9.5e-10 38.7 0.1 1.4e-09 38.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AAZ37016.1 - 0.0012 18.4 0.0 0.0021 17.6 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_trans_4_4 PF13579.6 AAZ37016.1 - 0.0057 17.1 0.7 0.37 11.2 0.1 2.3 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Eno-Rase_NADH_b PF12242.8 AAZ37016.1 - 0.13 12.0 0.1 0.25 11.1 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase HisKA_3 PF07730.13 AAZ37017.1 - 1.6e-15 57.3 1.0 5.1e-15 55.8 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase HATPase_c PF02518.26 AAZ37017.1 - 1.3e-05 25.7 0.1 4.1e-05 24.0 0.1 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_3 PF13492.6 AAZ37017.1 - 0.0003 21.1 0.0 0.0011 19.4 0.0 1.9 1 1 0 1 1 1 1 GAF domain HATPase_c_2 PF13581.6 AAZ37017.1 - 0.0059 16.6 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain DUF3392 PF11872.8 AAZ37018.1 - 4.1e-35 120.2 1.6 4.5e-35 120.1 1.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3392) DUF4896 PF16237.5 AAZ37018.1 - 0.052 13.4 0.7 0.11 12.3 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4896) Antimicrobial10 PF08105.11 AAZ37018.1 - 0.64 10.1 3.7 12 6.0 0.1 2.8 3 0 0 3 3 3 0 Metchnikowin family FCD PF07729.12 AAZ37019.1 - 3e-24 85.8 0.2 3e-24 85.8 0.2 2.3 2 1 0 2 2 2 1 FCD domain GntR PF00392.21 AAZ37019.1 - 2.2e-17 62.5 0.3 6.1e-17 61.0 0.3 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family PaaX PF07848.12 AAZ37019.1 - 0.00024 21.3 0.2 0.00074 19.7 0.1 1.8 2 0 0 2 2 2 1 PaaX-like protein Rrf2 PF02082.20 AAZ37019.1 - 0.00025 21.3 0.0 0.00061 20.1 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulator MarR_2 PF12802.7 AAZ37019.1 - 0.0069 16.3 0.5 0.025 14.4 0.1 2.1 2 0 0 2 2 2 1 MarR family TrmB PF01978.19 AAZ37019.1 - 0.02 14.8 0.0 0.056 13.3 0.0 1.8 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.6 AAZ37019.1 - 0.027 14.4 0.3 0.1 12.6 0.3 2.1 2 1 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_CodY PF08222.11 AAZ37019.1 - 0.061 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 CodY helix-turn-helix domain ABC2_membrane PF01061.24 AAZ37020.1 - 1.7e-07 30.9 14.6 2.3e-07 30.4 14.6 1.2 1 0 0 1 1 1 1 ABC-2 type transporter DUF1302 PF06980.11 AAZ37021.1 - 4.8e-228 758.4 7.0 5.5e-228 758.2 7.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1302) Biotin_lipoyl_2 PF13533.6 AAZ37022.1 - 1.4e-15 56.8 0.0 1.2e-13 50.6 0.0 2.9 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_D23 PF16576.5 AAZ37022.1 - 6.5e-15 54.9 0.5 1.8e-14 53.5 0.5 1.7 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AAZ37022.1 - 4.6e-07 30.5 1.9 0.009 16.7 0.1 3.1 3 0 0 3 3 3 2 HlyD family secretion protein PliI PF16743.5 AAZ37022.1 - 0.0081 15.9 0.0 0.022 14.5 0.0 1.7 1 0 0 1 1 1 1 Periplasmic lysozyme inhibitor of I-type lysozyme Biotin_lipoyl PF00364.22 AAZ37022.1 - 0.041 13.7 0.0 0.41 10.5 0.0 2.4 2 0 0 2 2 2 0 Biotin-requiring enzyme LigB PF02900.18 AAZ37023.1 - 6.8e-52 176.2 0.0 8.5e-52 175.9 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase DDE_Tnp_1 PF01609.21 AAZ37025.1 - 1.2e-35 123.1 1.5 2e-35 122.4 1.1 1.5 2 0 0 2 2 2 1 Transposase DDE domain DUF772 PF05598.11 AAZ37025.1 - 2.9e-19 68.9 0.1 6e-19 67.8 0.1 1.5 1 0 0 1 1 1 1 Transposase domain (DUF772) DDE_Tnp_1_6 PF13751.6 AAZ37025.1 - 1.3e-05 25.4 0.8 2.6e-05 24.4 0.8 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 AAZ37025.1 - 1.6e-05 24.9 0.1 2.7e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 AAZ37025.1 - 0.00082 19.1 0.1 0.0013 18.4 0.1 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Cys_rich_CWC PF14375.6 AAZ37026.1 - 2.3e-14 53.5 9.5 2.8e-14 53.2 9.5 1.1 1 0 0 1 1 1 1 Cysteine-rich CWC UBM PF14377.6 AAZ37026.1 - 0.00059 19.2 1.0 0.00092 18.6 1.0 1.3 1 0 0 1 1 1 1 Ubiquitin binding region AMP-binding PF00501.28 AAZ37027.1 - 3e-10 39.3 0.0 7.5e-08 31.4 0.0 2.0 2 0 0 2 2 2 2 AMP-binding enzyme AAA_16 PF13191.6 AAZ37028.1 - 0.0005 20.5 0.0 0.63 10.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 AAZ37028.1 - 0.00068 19.9 0.2 0.029 14.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 AAZ37028.1 - 0.00087 19.7 0.2 1.2 9.6 0.2 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 AAZ37028.1 - 0.001 19.0 9.6 0.098 12.5 9.1 2.4 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea KAP_NTPase PF07693.14 AAZ37028.1 - 0.0014 17.9 7.7 0.038 13.2 7.7 2.3 1 1 0 1 1 1 1 KAP family P-loop domain SRPRB PF09439.10 AAZ37028.1 - 0.0072 15.8 0.0 0.023 14.2 0.0 1.8 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_18 PF13238.6 AAZ37028.1 - 0.0084 16.7 0.9 1.7 9.2 0.0 3.0 2 1 1 3 3 3 1 AAA domain ABC_tran PF00005.27 AAZ37028.1 - 0.012 16.1 0.3 0.045 14.3 0.3 2.1 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.9 AAZ37028.1 - 0.015 15.1 0.6 0.049 13.4 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 AAZ37028.1 - 0.026 14.5 2.5 0.78 9.6 0.0 2.9 3 0 0 3 3 3 0 NACHT domain Roc PF08477.13 AAZ37028.1 - 0.034 14.4 0.1 0.12 12.6 0.1 2.0 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 AAZ37028.1 - 0.036 13.6 0.1 0.24 10.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF815 PF05673.13 AAZ37028.1 - 0.04 13.1 0.3 0.96 8.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MMR_HSR1 PF01926.23 AAZ37028.1 - 0.058 13.5 0.0 0.2 11.7 0.0 2.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase cobW PF02492.19 AAZ37028.1 - 0.073 12.7 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Plasmod_dom_1 PF09715.10 AAZ37028.1 - 0.29 11.2 4.0 5.7 7.1 0.4 3.0 2 0 0 2 2 2 0 Plasmodium protein of unknown function (Plasmod_dom_1) AAA_23 PF13476.6 AAZ37028.1 - 0.63 10.5 0.1 0.63 10.5 0.1 2.9 2 1 0 2 2 1 0 AAA domain AA_kinase PF00696.28 AAZ37029.1 - 2.1e-45 155.2 2.1 4.1e-45 154.2 1.1 1.9 2 0 0 2 2 2 1 Amino acid kinase family PUA PF01472.20 AAZ37029.1 - 1.1e-21 76.6 0.3 2.7e-21 75.3 0.3 1.7 1 0 0 1 1 1 1 PUA domain Transpeptidase PF00905.22 AAZ37030.1 - 4.2e-72 242.9 0.0 9.8e-72 241.7 0.0 1.5 2 0 0 2 2 2 1 Penicillin binding protein transpeptidase domain PBP_dimer PF03717.15 AAZ37030.1 - 4.1e-43 147.8 0.0 6.7e-43 147.1 0.0 1.4 1 0 0 1 1 1 1 Penicillin-binding Protein dimerisation domain MAP PF03642.13 AAZ37030.1 - 0.073 13.4 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 MAP domain LysR_substrate PF03466.20 AAZ37031.1 - 5.2e-41 140.3 0.4 7.4e-41 139.8 0.4 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ37031.1 - 5e-15 55.2 2.4 9e-15 54.4 2.4 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 AAZ37031.1 - 0.02 14.8 0.3 0.052 13.4 0.3 1.7 1 0 0 1 1 1 0 MarR family HTH_IclR PF09339.10 AAZ37031.1 - 0.03 14.1 1.7 0.068 13.0 0.5 2.2 2 0 0 2 2 2 0 IclR helix-turn-helix domain ExbD PF02472.16 AAZ37031.1 - 0.03 14.5 0.1 0.051 13.7 0.1 1.3 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR Sec8_exocyst PF04048.14 AAZ37031.1 - 0.064 13.1 0.0 0.096 12.6 0.0 1.2 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Inositol_P PF00459.25 AAZ37032.1 - 2.7e-50 171.4 0.0 3.2e-50 171.2 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.20 AAZ37032.1 - 0.0026 17.3 0.0 0.0039 16.7 0.0 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain NusB PF01029.18 AAZ37033.1 - 4.8e-34 117.5 0.0 5.8e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 NusB family SBP_bac_3 PF00497.20 AAZ37034.1 - 6e-70 235.2 0.9 7.2e-70 234.9 0.9 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 AAZ37034.1 - 2.5e-10 40.6 0.0 5e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site NMT1 PF09084.11 AAZ37034.1 - 0.0092 15.9 0.5 0.054 13.4 0.2 2.0 1 1 0 2 2 2 1 NMT1/THI5 like Heme_oxygenase PF01126.20 AAZ37035.1 - 2.3e-19 70.0 0.1 2.1e-14 53.8 0.0 2.0 2 0 0 2 2 2 2 Heme oxygenase OmdA PF13376.6 AAZ37035.1 - 0.65 10.1 6.0 3.9 7.6 0.1 2.6 3 0 0 3 3 3 0 Bacteriocin-protection, YdeI or OmpD-Associated UTRA PF07702.13 AAZ37036.1 - 5.7e-36 123.5 0.4 8.1e-36 123.0 0.4 1.2 1 0 0 1 1 1 1 UTRA domain GntR PF00392.21 AAZ37036.1 - 7.2e-17 60.8 0.1 1.4e-16 59.9 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_Crp_2 PF13545.6 AAZ37036.1 - 0.091 12.8 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain PALP PF00291.25 AAZ37037.1 - 7.5e-69 232.4 0.7 9e-69 232.1 0.7 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.26 AAZ37037.1 - 0.012 15.6 0.4 0.033 14.2 0.4 1.8 1 1 0 1 1 1 0 Zinc-binding dehydrogenase VWA_CoxE PF05762.14 AAZ37037.1 - 0.13 11.6 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein SPOR PF05036.13 AAZ37038.1 - 0.051 14.0 0.4 0.11 12.9 0.4 1.8 1 1 0 1 1 1 0 Sporulation related domain Phage_X PF05155.15 AAZ37039.1 - 2.6e-18 66.2 0.0 4.5e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Phage X family BACON PF13004.7 AAZ37039.1 - 0.077 13.0 0.1 0.2 11.6 0.1 1.7 1 0 0 1 1 1 0 Putative binding domain, N-terminal FtsX_ECD PF18075.1 AAZ37040.1 - 5.1e-16 59.1 0.0 7.4e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 FtsX extracellular domain POTRA_1 PF08478.10 AAZ37040.1 - 0.03 14.6 0.2 1.4 9.3 0.2 2.5 2 0 0 2 2 2 0 POTRA domain, FtsQ-type Hydrolase_6 PF13344.6 AAZ37041.1 - 3.5e-17 62.4 0.0 7.2e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AAZ37041.1 - 3.5e-14 52.6 0.1 4.1e-13 49.2 0.0 2.3 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.6 AAZ37041.1 - 4.1e-07 30.3 0.1 3e-06 27.4 0.0 2.1 2 1 1 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAZ37041.1 - 1e-06 29.2 0.3 0.007 16.7 0.0 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AAZ37041.1 - 0.14 11.8 0.0 2.9 7.6 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DnaB_bind PF10410.9 AAZ37042.1 - 0.036 14.3 0.1 2.2 8.5 0.0 2.3 2 0 0 2 2 2 0 DnaB-helicase binding domain of primase DUF815 PF05673.13 AAZ37043.1 - 4.8e-103 343.7 0.0 5.5e-103 343.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 AAZ37043.1 - 3.8e-06 27.4 0.7 1.4e-05 25.5 0.7 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 AAZ37043.1 - 0.00078 19.9 0.0 0.0021 18.5 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 AAZ37043.1 - 0.016 14.6 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.6 AAZ37043.1 - 0.018 15.3 0.0 0.032 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 AAZ37043.1 - 0.022 14.0 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin TrwB_AAD_bind PF10412.9 AAZ37043.1 - 0.041 12.8 0.0 0.064 12.2 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain RsgA_GTPase PF03193.16 AAZ37043.1 - 0.042 13.8 0.0 0.064 13.2 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase ABC_tran PF00005.27 AAZ37043.1 - 0.047 14.2 0.0 0.063 13.8 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 AAZ37043.1 - 0.078 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 AAZ37043.1 - 0.079 12.5 0.0 0.24 10.9 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region MMR_HSR1 PF01926.23 AAZ37043.1 - 0.15 12.2 0.0 0.45 10.6 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase DivIC PF04977.15 AAZ37044.1 - 2.8e-22 78.3 0.5 3.2e-22 78.1 0.5 1.0 1 0 0 1 1 1 1 Septum formation initiator ZapB PF06005.12 AAZ37044.1 - 0.028 14.9 1.9 0.037 14.5 1.9 1.1 1 0 0 1 1 1 0 Cell division protein ZapB Csm1_N PF18504.1 AAZ37044.1 - 0.071 13.5 2.3 0.1 13.0 1.2 1.6 1 1 0 1 1 1 0 Csm1 N-terminal domain YabA PF06156.13 AAZ37044.1 - 0.093 13.4 0.8 0.11 13.2 0.8 1.1 1 0 0 1 1 1 0 Initiation control protein YabA HALZ PF02183.18 AAZ37044.1 - 0.24 11.6 2.0 0.3 11.3 0.6 1.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper PdxA PF04166.12 AAZ37045.1 - 2.2e-104 348.8 0.0 2.6e-104 348.6 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthetic protein PdxA DUF3792 PF12670.7 AAZ37046.1 - 0.0016 18.6 14.5 0.0016 18.6 14.5 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF3792) DUF1266 PF06889.11 AAZ37046.1 - 0.0031 17.6 4.1 0.0047 17.0 4.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1266) DUF883 PF05957.13 AAZ37046.1 - 0.016 15.8 7.3 0.016 15.8 7.3 3.6 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) DUF2207 PF09972.9 AAZ37046.1 - 0.032 13.0 6.0 0.1 11.4 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) SNARE PF05739.19 AAZ37046.1 - 0.055 13.5 2.1 4.3 7.4 0.0 3.4 3 0 0 3 3 3 0 SNARE domain DUF1761 PF08570.10 AAZ37046.1 - 0.16 12.2 8.2 1.9 8.8 5.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1761) DUF5518 PF17647.1 AAZ37046.1 - 0.34 11.1 27.1 2 8.6 13.6 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5518) BSMAP PF12280.8 AAZ37046.1 - 1.9 8.7 4.9 41 4.3 4.9 2.1 1 1 0 1 1 1 0 Brain specific membrane anchored protein FtsA PF14450.6 AAZ37047.1 - 2.4e-39 133.9 1.9 9.5e-26 90.2 0.0 2.2 2 0 0 2 2 2 2 Cell division protein FtsA SHS2_FTSA PF02491.20 AAZ37047.1 - 1.3e-32 112.0 2.3 2e-32 111.4 0.3 2.3 3 0 0 3 3 3 1 SHS2 domain inserted in FTSA MreB_Mbl PF06723.13 AAZ37047.1 - 2e-16 59.7 6.8 8.4e-16 57.7 0.3 2.8 2 2 1 3 3 3 2 MreB/Mbl protein EutA PF06277.11 AAZ37047.1 - 5.1e-07 28.9 3.3 1.7e-06 27.2 0.2 2.9 3 1 1 4 4 4 1 Ethanolamine utilisation protein EutA PilM_2 PF11104.8 AAZ37047.1 - 2.9e-06 26.5 1.0 0.0012 17.9 1.2 3.2 2 1 0 2 2 2 1 Type IV pilus assembly protein PilM; DDR PF08841.10 AAZ37047.1 - 5.2e-05 22.4 0.5 0.0001 21.4 0.5 1.6 1 0 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain HSP70 PF00012.20 AAZ37047.1 - 0.00056 18.2 0.7 0.0051 15.1 0.1 2.5 2 1 0 2 2 2 1 Hsp70 protein GCS2 PF04107.13 AAZ37047.1 - 0.011 15.0 0.1 0.055 12.8 0.0 1.9 2 0 0 2 2 2 0 Glutamate-cysteine ligase family 2(GCS2) SrfB PF07520.11 AAZ37047.1 - 0.038 11.9 0.2 0.053 11.4 0.2 1.1 1 0 0 1 1 1 0 Virulence factor SrfB Actin PF00022.19 AAZ37047.1 - 0.068 11.8 0.2 0.34 9.5 0.1 2.2 2 1 0 2 2 2 0 Actin PilO PF04350.13 AAZ37048.1 - 2e-55 187.0 0.0 2.4e-55 186.7 0.0 1.1 1 0 0 1 1 1 1 Pilus assembly protein, PilO T2SSM PF04612.12 AAZ37048.1 - 0.025 14.6 0.1 0.077 13.0 0.0 1.8 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M DUF2232 PF09991.9 AAZ37048.1 - 0.033 13.4 0.2 0.051 12.8 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Gemini_mov PF01708.16 AAZ37048.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Geminivirus putative movement protein Tnp_P_element_C PF12596.8 AAZ37048.1 - 0.13 12.8 0.1 0.21 12.2 0.1 1.2 1 0 0 1 1 1 0 87kDa Transposase RNase_T PF00929.24 AAZ37049.1 - 5.2e-34 118.2 0.0 6.1e-34 117.9 0.0 1.0 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 AAZ37049.1 - 2.8e-05 24.1 0.0 3.9e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 3' exoribonuclease, RNase T-like ABC_sub_bind PF04392.12 AAZ37049.1 - 0.1 11.9 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 ABC transporter substrate binding protein CAF1 PF04857.20 AAZ37049.1 - 0.2 10.8 0.1 0.55 9.3 0.0 1.8 2 0 0 2 2 2 0 CAF1 family ribonuclease Abhydrolase_1 PF00561.20 AAZ37050.1 - 6.3e-24 85.0 0.0 3.3e-23 82.6 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAZ37050.1 - 4.5e-23 83.0 1.2 5.3e-23 82.8 1.2 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAZ37050.1 - 1.1e-15 57.5 0.0 1.6e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 AAZ37050.1 - 6.8e-08 31.5 0.0 1e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Ndr family FSH1 PF03959.13 AAZ37050.1 - 0.00054 19.7 0.0 0.0013 18.5 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 AAZ37050.1 - 0.0017 18.2 2.0 0.0098 15.7 0.1 2.4 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Palm_thioest PF02089.15 AAZ37050.1 - 0.0017 18.3 0.0 0.002 18.0 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.11 AAZ37050.1 - 0.0019 17.6 0.0 0.0057 16.0 0.0 1.7 2 1 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) PGAP1 PF07819.13 AAZ37050.1 - 0.011 15.5 0.1 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 PGAP1-like protein Esterase PF00756.20 AAZ37050.1 - 0.047 13.3 0.0 0.065 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Abhydrolase_4 PF08386.10 AAZ37050.1 - 0.048 13.8 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 TAP-like protein Peptidase_S9 PF00326.21 AAZ37050.1 - 0.054 13.0 0.0 3.2 7.2 0.0 2.3 1 1 0 1 1 1 0 Prolyl oligopeptidase family DLH PF01738.18 AAZ37050.1 - 0.13 11.8 0.0 1.4 8.4 0.0 2.1 1 1 0 2 2 2 0 Dienelactone hydrolase family FUSC-like PF12805.7 AAZ37051.1 - 1.5e-114 381.9 16.7 1.3e-113 378.8 3.3 3.1 3 0 0 3 3 3 3 FUSC-like inner membrane protein yccS FUSC_2 PF13515.6 AAZ37051.1 - 1.2e-19 70.7 28.1 1.9e-19 70.1 11.7 2.7 2 0 0 2 2 2 2 Fusaric acid resistance protein-like FUSC PF04632.12 AAZ37051.1 - 1e-10 40.8 11.7 1e-10 40.8 11.7 3.2 4 0 0 4 4 4 1 Fusaric acid resistance protein family ALMT PF11744.8 AAZ37051.1 - 0.00041 19.3 2.9 0.0042 16.0 2.9 2.4 1 1 0 1 1 1 1 Aluminium activated malate transporter ArAE_1 PF06081.11 AAZ37051.1 - 0.0016 18.6 4.0 0.0016 18.6 4.0 2.3 2 0 0 2 2 2 1 Aromatic acid exporter family member 1 Peripla_BP_3 PF13377.6 AAZ37052.1 - 2.3e-34 119.1 1.7 4.3e-34 118.2 0.4 1.9 2 0 0 2 2 2 1 Periplasmic binding protein-like domain HTH_18 PF12833.7 AAZ37052.1 - 3.2e-19 69.0 0.2 7.9e-19 67.7 0.2 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAZ37052.1 - 2.3e-17 62.6 0.0 2.7e-12 46.5 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Peripla_BP_4 PF13407.6 AAZ37052.1 - 1.6e-07 31.2 0.0 2.4e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 AAZ37052.1 - 0.00019 21.0 0.0 0.00031 20.3 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family HTH_23 PF13384.6 AAZ37052.1 - 0.033 14.0 0.1 0.25 11.2 0.1 2.4 2 0 0 2 2 2 0 Homeodomain-like domain DUF3263 PF11662.8 AAZ37052.1 - 0.057 13.3 0.0 0.36 10.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3263) Transposase_mut PF00872.18 AAZ37053.1 - 1.3e-06 27.5 0.0 1.6e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Transposase, Mutator family Glycos_transf_1 PF00534.20 AAZ37054.1 - 1.1e-30 106.4 0.0 1.6e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAZ37054.1 - 7.2e-26 91.2 0.0 2.4e-25 89.5 0.1 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAZ37054.1 - 3e-10 40.4 0.1 1.6e-08 34.7 0.1 2.3 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 AAZ37054.1 - 0.0097 16.3 0.0 0.019 15.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF900 PF05990.12 AAZ37054.1 - 0.016 14.7 0.0 0.042 13.4 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) TOBE PF03459.17 AAZ37055.1 - 2.5e-15 56.5 1.0 2.7e-15 56.4 1.0 1.0 1 0 0 1 1 1 1 TOBE domain FliD_C PF07195.12 AAZ37056.1 - 1.1e-56 191.9 10.4 1.1e-56 191.9 10.4 2.8 3 0 0 3 3 3 1 Flagellar hook-associated protein 2 C-terminus FliD_N PF02465.18 AAZ37056.1 - 4.6e-17 62.5 3.8 4.6e-17 62.5 3.8 5.8 2 1 1 3 3 3 1 Flagellar hook-associated protein 2 N-terminus Flagellin_IN PF07196.13 AAZ37056.1 - 7.6e-11 42.0 6.3 7.6e-11 42.0 6.3 5.9 6 1 0 6 6 6 1 Flagellin hook IN motif DUF4854 PF16146.5 AAZ37056.1 - 0.75 10.2 7.1 3.3 8.1 0.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4854) Tape_meas_lam_C PF09718.10 AAZ37056.1 - 1.8 8.7 9.8 2.1 8.5 0.2 3.6 3 0 0 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Transposase_mut PF00872.18 AAZ37057.1 - 2.8e-117 391.8 0.0 3.4e-117 391.5 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ37057.1 - 7.7e-05 23.0 0.0 0.00021 21.6 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain DUF4844 PF16133.5 AAZ37057.1 - 0.23 12.0 0.0 0.55 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) MaoC_dehydratas PF01575.19 AAZ37058.1 - 3.1e-16 59.1 0.0 4.8e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 AAZ37058.1 - 1.3e-05 25.3 0.0 0.0066 16.6 0.0 2.2 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase Exo_endo_phos PF03372.23 AAZ37059.1 - 9e-10 38.5 0.3 1.1e-09 38.1 0.3 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CbiK PF06180.11 AAZ37059.1 - 0.093 12.0 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Cobalt chelatase (CbiK) RVT_1 PF00078.27 AAZ37060.1 - 2.9e-21 76.0 0.0 6.9e-21 74.8 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) ABC_tran PF00005.27 AAZ37061.1 - 1.1e-61 207.3 0.1 1.6e-30 106.4 0.0 2.3 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 AAZ37061.1 - 3.1e-17 62.7 0.0 5.4e-09 35.8 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain oligo_HPY PF08352.12 AAZ37061.1 - 5.6e-14 52.4 0.0 1.2e-05 25.7 0.0 2.5 2 0 0 2 2 2 2 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 AAZ37061.1 - 1.1e-11 45.2 12.4 5.5e-06 26.4 0.1 3.9 2 2 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AAZ37061.1 - 8.3e-08 31.9 0.2 0.0043 16.8 0.1 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 AAZ37061.1 - 1.2e-06 29.0 4.5 0.01 16.2 0.5 2.7 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 AAZ37061.1 - 1.2e-05 25.6 9.0 0.016 15.5 0.5 4.0 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.6 AAZ37061.1 - 1.4e-05 24.8 0.1 1.4 8.5 0.0 4.0 4 0 0 4 4 4 2 AAA domain RsgA_GTPase PF03193.16 AAZ37061.1 - 6.4e-05 22.9 0.2 0.45 10.4 0.2 2.4 2 0 0 2 2 2 2 RsgA GTPase Mg_chelatase PF01078.21 AAZ37061.1 - 0.0004 19.8 0.1 0.51 9.7 0.0 2.7 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI ATP-synt_ab PF00006.25 AAZ37061.1 - 0.00049 19.8 0.1 0.65 9.6 0.0 2.5 2 1 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.29 AAZ37061.1 - 0.00049 20.5 0.0 4 7.9 0.0 3.4 3 1 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 AAZ37061.1 - 0.00061 20.0 1.8 0.31 11.1 0.0 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain ATPase PF06745.13 AAZ37061.1 - 0.00097 18.5 1.2 0.58 9.5 0.1 3.2 3 0 0 3 3 3 1 KaiC AAA_7 PF12775.7 AAZ37061.1 - 0.001 18.6 0.0 0.32 10.5 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_5 PF07728.14 AAZ37061.1 - 0.0011 18.9 0.2 1.2 9.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 AAZ37061.1 - 0.0016 18.4 1.4 1 9.2 0.0 2.9 3 0 0 3 3 2 1 NACHT domain SbcCD_C PF13558.6 AAZ37061.1 - 0.0029 17.8 0.1 0.55 10.5 0.0 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Sigma54_activat PF00158.26 AAZ37061.1 - 0.0029 17.3 0.7 0.71 9.6 0.0 3.0 3 0 0 3 3 3 1 Sigma-54 interaction domain AIG1 PF04548.16 AAZ37061.1 - 0.0032 16.8 0.2 0.15 11.4 0.0 2.4 2 0 0 2 2 2 1 AIG1 family IstB_IS21 PF01695.17 AAZ37061.1 - 0.0035 17.1 1.6 2.4 7.9 0.0 3.2 4 0 0 4 4 3 1 IstB-like ATP binding protein NB-ARC PF00931.22 AAZ37061.1 - 0.0049 16.1 0.0 2.6 7.2 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain DUF2075 PF09848.9 AAZ37061.1 - 0.0065 15.7 0.0 0.91 8.7 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 AAZ37061.1 - 0.0066 16.6 0.6 1.9 8.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 AAZ37061.1 - 0.02 15.3 0.0 6 7.3 0.0 2.4 2 0 0 2 2 2 0 RNA helicase ABC_ATPase PF09818.9 AAZ37061.1 - 0.027 13.3 0.4 6.6 5.4 0.0 3.3 3 1 0 3 3 3 0 Predicted ATPase of the ABC class FtsK_SpoIIIE PF01580.18 AAZ37061.1 - 0.031 13.6 0.1 1.6 8.1 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_24 PF13479.6 AAZ37061.1 - 0.039 13.7 0.6 7.7 6.2 0.2 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 AAZ37061.1 - 0.043 13.9 0.2 2.8 8.0 0.0 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_23 PF13476.6 AAZ37061.1 - 0.051 14.1 0.0 2 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 AAZ37061.1 - 0.072 13.0 0.3 7.7 6.4 0.1 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase PRK PF00485.18 AAZ37061.1 - 0.11 12.2 0.2 4.6 6.9 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Pox_A32 PF04665.12 AAZ37061.1 - 0.17 11.3 3.0 5.5 6.4 0.0 2.6 3 0 0 3 3 3 0 Poxvirus A32 protein CbiA PF01656.23 AAZ37061.1 - 2.5 8.2 4.8 54 3.8 0.0 3.5 3 2 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2986 PF11661.8 AAZ37062.1 - 5e-18 65.3 11.2 5.7e-18 65.2 11.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2986) MadM PF03818.13 AAZ37063.1 - 5.4e-28 96.6 4.7 5.4e-28 96.6 4.7 3.2 3 1 0 3 3 3 2 Malonate/sodium symporter MadM subunit BCAS3 PF12490.8 AAZ37063.1 - 0.055 13.0 0.1 0.081 12.4 0.1 1.2 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 CHDCT2 PF08074.11 AAZ37064.1 - 5.5 7.1 6.7 1.9 8.6 2.6 2.4 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain DrsE PF02635.15 AAZ37065.1 - 4.3e-20 72.2 0.0 4.7e-20 72.1 0.0 1.0 1 0 0 1 1 1 1 DsrE/DsrF-like family Peripla_BP_4 PF13407.6 AAZ37065.1 - 0.04 13.5 0.0 0.048 13.2 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein domain Acetyltransf_1 PF00583.25 AAZ37066.1 - 2.1e-09 37.6 0.0 2.5e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAZ37066.1 - 8.4e-09 35.7 0.0 1.2e-08 35.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAZ37066.1 - 2.7e-07 30.6 0.0 3.4e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AAZ37066.1 - 0.0017 18.5 0.0 0.0029 17.7 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 AAZ37066.1 - 0.0049 16.8 0.0 0.0076 16.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein zf-TFIIB PF13453.6 AAZ37066.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Transcription factor zinc-finger Wzy_C PF04932.15 AAZ37067.1 - 3.8e-06 26.6 5.3 3.8e-06 26.6 5.3 4.1 3 2 0 3 3 3 1 O-Antigen ligase DUF1673 PF07895.11 AAZ37067.1 - 1.6 8.4 4.1 4.1 7.1 4.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) DUF4234 PF14018.6 AAZ37068.1 - 0.51 10.5 4.4 0.51 10.5 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) ABC_tran PF00005.27 AAZ37069.1 - 3.2e-66 222.0 0.0 1.7e-33 116.0 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 AAZ37069.1 - 1.6e-17 64.3 10.9 5.4e-06 26.4 0.3 4.1 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system oligo_HPY PF08352.12 AAZ37069.1 - 1.5e-12 47.9 0.0 8.4e-06 26.2 0.0 2.4 2 0 0 2 2 2 2 Oligopeptide/dipeptide transporter, C-terminal region SMC_N PF02463.19 AAZ37069.1 - 5.6e-11 42.3 2.5 0.00051 19.6 0.1 3.9 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAZ37069.1 - 2.4e-10 40.0 0.1 8.2e-05 22.3 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 AAZ37069.1 - 1.2e-08 35.6 3.4 0.00038 20.9 0.1 2.6 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 AAZ37069.1 - 1.6e-08 34.7 0.1 0.00038 20.4 0.0 2.7 3 0 0 3 3 2 2 RsgA GTPase AAA_22 PF13401.6 AAZ37069.1 - 3.2e-08 34.0 5.8 0.00068 19.9 0.2 3.8 2 2 0 2 2 2 2 AAA domain AAA_23 PF13476.6 AAZ37069.1 - 5.5e-07 30.3 0.1 0.012 16.2 0.1 2.2 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 AAZ37069.1 - 4.1e-06 26.9 0.1 0.0047 17.0 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase NACHT PF05729.12 AAZ37069.1 - 1e-05 25.5 0.4 0.042 13.8 0.0 2.7 2 0 0 2 2 2 2 NACHT domain IstB_IS21 PF01695.17 AAZ37069.1 - 1.2e-05 25.1 0.4 0.031 14.0 0.0 2.8 3 0 0 3 3 2 2 IstB-like ATP binding protein T2SSE PF00437.20 AAZ37069.1 - 1.8e-05 24.0 0.2 0.034 13.2 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF87 PF01935.17 AAZ37069.1 - 7.6e-05 22.9 0.8 0.13 12.4 0.1 2.5 2 0 0 2 2 2 2 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 AAZ37069.1 - 0.0001 21.8 0.1 0.5 9.7 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family TniB PF05621.11 AAZ37069.1 - 0.00011 21.7 1.2 6.1 6.2 0.0 4.3 4 1 0 4 4 4 0 Bacterial TniB protein ABC_ATPase PF09818.9 AAZ37069.1 - 0.00012 21.0 6.3 1.5 7.5 0.1 4.2 4 2 0 4 4 4 3 Predicted ATPase of the ABC class Mg_chelatase PF01078.21 AAZ37069.1 - 0.00021 20.7 0.1 0.0097 15.3 0.0 2.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 AAZ37069.1 - 0.00031 20.5 0.1 0.36 10.5 0.1 2.3 2 0 0 2 2 2 2 AAA domain APS_kinase PF01583.20 AAZ37069.1 - 0.00098 19.0 0.2 0.43 10.5 0.0 2.3 2 0 0 2 2 2 1 Adenylylsulphate kinase Sigma54_activat PF00158.26 AAZ37069.1 - 0.001 18.8 2.9 0.14 11.9 0.0 3.5 4 0 0 4 4 3 1 Sigma-54 interaction domain AAA_33 PF13671.6 AAZ37069.1 - 0.0015 18.7 0.1 0.81 9.8 0.0 2.8 3 0 0 3 3 2 1 AAA domain DUF3987 PF13148.6 AAZ37069.1 - 0.0016 17.5 0.0 1 8.3 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3987) Dynamin_N PF00350.23 AAZ37069.1 - 0.002 18.2 1.2 0.023 14.7 0.2 2.2 2 0 0 2 2 2 1 Dynamin family ATP-synt_ab PF00006.25 AAZ37069.1 - 0.0033 17.1 0.0 0.36 10.4 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.6 AAZ37069.1 - 0.0034 17.1 1.5 3.6 7.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_15 PF13175.6 AAZ37069.1 - 0.0051 16.6 0.1 1.9 8.1 0.0 2.4 3 0 0 3 3 2 1 AAA ATPase domain Zeta_toxin PF06414.12 AAZ37069.1 - 0.0052 16.1 0.1 2 7.6 0.1 2.3 2 0 0 2 2 2 1 Zeta toxin AIG1 PF04548.16 AAZ37069.1 - 0.0055 16.0 0.2 0.16 11.2 0.0 2.6 3 0 0 3 3 2 1 AIG1 family NB-ARC PF00931.22 AAZ37069.1 - 0.0057 15.9 0.1 0.35 10.0 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain AAA_7 PF12775.7 AAZ37069.1 - 0.0074 15.8 0.2 0.37 10.3 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_5 PF07728.14 AAZ37069.1 - 0.0082 16.1 1.1 0.29 11.1 0.1 2.8 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 AAZ37069.1 - 0.009 16.4 0.1 1.4 9.3 0.0 2.4 2 0 0 2 2 2 1 RNA helicase SbcCD_C PF13558.6 AAZ37069.1 - 0.011 16.0 0.6 2.2 8.6 0.2 3.7 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit PRK PF00485.18 AAZ37069.1 - 0.014 15.1 0.1 2.6 7.8 0.0 2.7 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family Propep_M14 PF02244.16 AAZ37069.1 - 0.015 15.7 0.1 4.6 7.7 0.0 2.8 3 0 0 3 3 2 0 Carboxypeptidase activation peptide AAA_25 PF13481.6 AAZ37069.1 - 0.017 14.7 4.2 0.53 9.8 0.9 3.4 3 1 0 3 3 3 0 AAA domain Septin PF00735.18 AAZ37069.1 - 0.02 14.2 0.3 1.2 8.4 0.1 2.2 2 0 0 2 2 2 0 Septin AAA_10 PF12846.7 AAZ37069.1 - 0.022 13.7 0.0 2.1 7.2 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain ATPase PF06745.13 AAZ37069.1 - 0.024 14.0 0.7 1.3 8.3 0.0 2.8 3 0 0 3 3 3 0 KaiC NTPase_1 PF03266.15 AAZ37069.1 - 0.029 14.3 0.7 0.7 9.8 0.1 2.4 2 0 0 2 2 2 0 NTPase G-alpha PF00503.20 AAZ37069.1 - 0.035 13.2 0.0 7.6 5.6 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit AAA_18 PF13238.6 AAZ37069.1 - 0.043 14.4 0.4 3.1 8.4 0.1 2.6 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 AAZ37069.1 - 0.077 13.2 0.4 3.7 7.8 0.1 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase IIGP PF05049.13 AAZ37069.1 - 0.077 12.0 0.6 1 8.3 0.1 2.1 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) MobB PF03205.14 AAZ37069.1 - 0.082 12.8 0.3 3.1 7.7 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B TsaE PF02367.17 AAZ37069.1 - 0.18 11.8 0.1 4.1 7.4 0.1 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Pox_A32 PF04665.12 AAZ37069.1 - 0.23 10.9 1.2 15 4.9 0.0 2.6 3 0 0 3 3 3 0 Poxvirus A32 protein CbiA PF01656.23 AAZ37069.1 - 0.34 11.0 1.0 4.9 7.2 0.1 2.9 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain cobW PF02492.19 AAZ37069.1 - 0.45 10.1 2.4 9.3 5.8 0.1 2.7 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain DUF480 PF04337.12 AAZ37070.1 - 1.5e-52 177.7 0.4 2.5e-52 176.9 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF480 HalX PF08663.10 AAZ37070.1 - 0.042 14.2 2.2 0.042 14.2 2.2 2.4 2 1 0 2 2 2 0 HalX domain Tho1_MOS11_C PF18592.1 AAZ37070.1 - 0.18 11.6 0.5 1.7 8.5 0.0 2.2 2 0 0 2 2 2 0 Tho1/MOS11 C-terminal domain ABC_tran_CTD PF16326.5 AAZ37070.1 - 0.31 11.3 4.6 0.66 10.3 0.5 2.6 1 1 0 2 2 2 0 ABC transporter C-terminal domain MerR-DNA-bind PF09278.11 AAZ37070.1 - 2 9.0 9.3 0.47 11.0 4.7 2.1 2 0 0 2 2 2 0 MerR, DNA binding Trp_oprn_chp PF09534.10 AAZ37071.1 - 0.0026 17.6 5.4 0.005 16.7 5.4 1.4 1 1 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4010 PF13194.6 AAZ37071.1 - 0.01 15.5 0.2 0.012 15.3 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4010) Phage_holin_3_6 PF07332.11 AAZ37071.1 - 0.012 15.6 4.1 0.015 15.4 4.1 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III LtrA PF06772.11 AAZ37071.1 - 0.019 14.2 0.2 0.021 14.1 0.2 1.0 1 0 0 1 1 1 0 Bacterial low temperature requirement A protein (LtrA) GT87 PF09594.10 AAZ37071.1 - 0.02 14.6 3.7 0.029 14.1 2.0 1.7 1 1 1 2 2 2 0 Glycosyltransferase family 87 DUF4386 PF14329.6 AAZ37071.1 - 0.028 14.3 4.2 0.033 14.0 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4386) Saf_2TM PF18303.1 AAZ37071.1 - 0.041 13.5 0.0 0.052 13.1 0.0 1.1 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain DUF3040 PF11239.8 AAZ37071.1 - 1.6 9.0 9.2 13 6.2 9.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) DUF4381 PF14316.6 AAZ37071.1 - 3.5 7.9 6.4 0.78 10.0 1.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4381) FAD_binding_9 PF08021.11 AAZ37072.1 - 8.3e-40 135.8 0.0 2.3e-39 134.3 0.0 1.7 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain SIP PF04954.13 AAZ37072.1 - 4e-33 114.5 0.3 7.5e-33 113.6 0.3 1.4 1 0 0 1 1 1 1 Siderophore-interacting protein FAD_binding_6 PF00970.24 AAZ37072.1 - 0.012 16.0 0.0 0.11 12.8 0.0 2.2 1 1 0 1 1 1 0 Oxidoreductase FAD-binding domain ZapA PF05164.13 AAZ37073.1 - 1.2e-13 51.2 0.6 1.5e-13 50.9 0.6 1.1 1 0 0 1 1 1 1 Cell division protein ZapA ADH_zinc_N_2 PF13602.6 AAZ37074.1 - 0.067 14.3 0.0 0.072 14.1 0.0 1.1 1 0 0 1 1 1 0 Zinc-binding dehydrogenase YXWGXW PF12779.7 AAZ37075.1 - 1.8e-07 31.2 15.1 1.8e-07 31.2 15.1 2.3 2 0 0 2 2 2 2 YXWGXW repeat (2 copies) OEP PF02321.18 AAZ37076.1 - 4.2e-17 62.6 10.7 4.2e-17 62.6 10.7 1.7 2 0 0 2 2 2 1 Outer membrane efflux protein Methyltransf_11 PF08241.12 AAZ37077.1 - 1.8e-13 51.0 0.3 1.2e-12 48.3 0.0 2.4 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAZ37077.1 - 9.5e-13 48.3 0.2 3.7e-12 46.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAZ37077.1 - 2.6e-11 44.1 2.2 3.3e-10 40.5 0.0 3.0 3 1 0 3 3 3 1 Methyltransferase domain MetW PF07021.12 AAZ37077.1 - 2e-07 30.8 0.0 4.3e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_12 PF08242.12 AAZ37077.1 - 2.8e-05 24.8 0.2 0.00014 22.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAZ37077.1 - 5.2e-05 23.1 0.3 0.00035 20.4 0.0 2.5 3 1 0 3 3 3 1 Methyltransferase domain AdoMet_MTase PF07757.13 AAZ37077.1 - 0.11 12.9 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Cytochrom_B562 PF07361.11 AAZ37077.1 - 0.11 13.2 4.4 0.26 11.9 4.3 1.7 1 1 0 1 1 1 0 Cytochrome b562 DUF3584 PF12128.8 AAZ37077.1 - 0.15 9.5 17.1 0.21 9.1 17.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Syntaxin-6_N PF09177.11 AAZ37077.1 - 0.29 11.7 8.4 0.13 12.9 0.7 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF4140 PF13600.6 AAZ37077.1 - 0.89 10.0 13.9 0.53 10.8 8.1 2.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Kdo PF06293.14 AAZ37078.1 - 0.00033 20.1 0.2 0.00074 18.9 0.2 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pec_lyase_C PF00544.19 AAZ37079.1 - 1.2e-32 113.2 5.2 1.8e-32 112.6 5.2 1.2 1 0 0 1 1 1 1 Pectate lyase Ndc1_Nup PF09531.10 AAZ37079.1 - 0.38 9.4 6.3 0.49 9.0 6.3 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Transposase_mut PF00872.18 AAZ37080.1 - 4.7e-115 384.5 0.0 5.9e-115 384.1 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ37080.1 - 7.7e-05 23.0 0.0 0.00021 21.6 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain FUSC PF04632.12 AAZ37081.1 - 1.4e-191 638.4 33.3 1.8e-191 638.1 33.3 1.0 1 0 0 1 1 1 1 Fusaric acid resistance protein family FUSC_2 PF13515.6 AAZ37081.1 - 6.9e-17 61.8 10.9 6.9e-17 61.8 10.9 3.2 2 1 1 3 3 3 2 Fusaric acid resistance protein-like ALMT PF11744.8 AAZ37081.1 - 2.1e-05 23.6 3.2 4e-05 22.7 3.2 1.4 1 0 0 1 1 1 1 Aluminium activated malate transporter GATase_4 PF13230.6 AAZ37082.1 - 7.7e-110 366.1 0.0 8.5e-110 365.9 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 AAZ37082.1 - 9.7e-05 22.6 0.0 0.00014 22.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain FliM PF02154.15 AAZ37083.1 - 5.8e-73 244.9 0.1 1.3e-72 243.7 0.1 1.6 2 0 0 2 2 2 1 Flagellar motor switch protein FliM FliMN_C PF01052.20 AAZ37083.1 - 3.8e-16 58.8 0.1 7.5e-16 57.9 0.1 1.5 1 0 0 1 1 1 1 Type III flagellar switch regulator (C-ring) FliN C-term EPL1 PF10513.9 AAZ37083.1 - 0.077 13.4 0.1 0.16 12.4 0.1 1.4 1 0 0 1 1 1 0 Enhancer of polycomb-like HAD_2 PF13419.6 AAZ37084.1 - 2.9e-19 69.8 0.1 4.5e-18 65.9 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAZ37084.1 - 2.6e-16 60.6 1.1 1.9e-14 54.4 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 AAZ37084.1 - 5.2e-09 36.8 3.1 9.7e-08 32.6 3.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AAZ37084.1 - 1.9e-07 31.0 0.0 3.9e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 AAZ37084.1 - 0.043 13.9 0.0 0.17 12.0 0.0 2.0 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Polysacc_deac_1 PF01522.21 AAZ37085.1 - 2.6e-15 56.4 0.0 3.8e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 AAZ37085.1 - 0.064 12.9 0.0 5.4 6.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2334) HrpE PF06188.12 AAZ37086.1 - 1.8e-64 217.1 19.6 2e-64 217.0 19.6 1.0 1 0 0 1 1 1 1 HrpE/YscL/FliH and V-type ATPase subunit E FliH PF02108.16 AAZ37086.1 - 7.9e-06 26.0 1.6 1.5e-05 25.0 1.5 1.6 1 1 0 1 1 1 1 Flagellar assembly protein FliH RbsD_FucU PF05025.13 AAZ37086.1 - 0.025 15.0 0.5 0.036 14.5 0.5 1.2 1 0 0 1 1 1 0 RbsD / FucU transport protein family TetR_N PF00440.23 AAZ37087.1 - 4e-13 48.9 0.0 1e-12 47.6 0.0 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family B-block_TFIIIC PF04182.12 AAZ37087.1 - 0.03 14.5 0.0 0.076 13.2 0.0 1.6 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC Maf PF02545.14 AAZ37088.1 - 2.8e-42 144.4 0.0 3.2e-42 144.2 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein PYC_OADA PF02436.18 AAZ37089.1 - 1.6e-56 191.2 0.0 2.9e-56 190.4 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain HMGL-like PF00682.19 AAZ37089.1 - 6.1e-49 166.9 0.1 8.9e-49 166.4 0.1 1.2 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 AAZ37089.1 - 5.4e-17 61.4 5.1 1.2e-16 60.2 5.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 AAZ37089.1 - 8.7e-14 51.1 1.9 5.4e-07 29.3 0.2 2.8 2 0 0 2 2 2 2 Biotin-lipoyl like RnfC_N PF13375.6 AAZ37089.1 - 1.1e-05 25.4 2.2 7.6e-05 22.6 2.5 2.3 2 1 0 2 2 2 1 RnfC Barrel sandwich hybrid domain HlyD_3 PF13437.6 AAZ37089.1 - 0.00063 20.4 2.8 0.18 12.5 0.5 3.4 4 0 0 4 4 4 1 HlyD family secretion protein HlyD_D23 PF16576.5 AAZ37089.1 - 0.00065 19.0 2.6 0.05 12.8 0.2 2.9 2 1 1 3 3 3 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion NQRA PF05896.11 AAZ37089.1 - 0.0033 16.9 0.5 0.0069 15.8 0.5 1.5 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) PTS_EIIA_1 PF00358.20 AAZ37089.1 - 0.0061 16.3 0.4 2.3 8.0 0.1 2.6 1 1 1 2 2 2 2 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 QRPTase_N PF02749.16 AAZ37089.1 - 0.022 14.8 0.5 2.5 8.2 0.1 2.6 1 1 1 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain GCV_H PF01597.19 AAZ37089.1 - 0.045 13.6 0.8 0.045 13.6 0.8 2.0 2 0 0 2 2 2 0 Glycine cleavage H-protein 53-BP1_Tudor PF09038.10 AAZ37089.1 - 0.11 12.4 0.1 0.26 11.3 0.1 1.6 1 0 0 1 1 1 0 Tumour suppressor p53-binding protein-1 Tudor YqfD PF06898.11 AAZ37089.1 - 0.99 8.2 2.8 4.3 6.1 1.3 2.2 1 1 1 2 2 2 0 Putative stage IV sporulation protein YqfD LysE PF01810.18 AAZ37091.1 - 8.7e-20 71.0 12.8 8.7e-20 71.0 12.8 1.3 2 0 0 2 2 2 1 LysE type translocator DUF3392 PF11872.8 AAZ37091.1 - 0.05 13.9 1.2 0.05 13.9 1.2 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3392) TerC PF03741.16 AAZ37091.1 - 0.053 13.2 5.5 0.095 12.4 5.5 1.7 1 1 0 1 1 1 0 Integral membrane protein TerC family PsbN PF02468.15 AAZ37091.1 - 4.2 7.3 7.4 6.2 6.8 0.0 4.1 4 0 0 4 4 4 0 Photosystem II reaction centre N protein (psbN) HIT PF01230.23 AAZ37092.1 - 9.2e-17 61.6 0.0 1.6e-16 60.8 0.0 1.4 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 AAZ37092.1 - 0.038 14.5 0.0 0.066 13.7 0.0 1.3 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding Abhydrolase_1 PF00561.20 AAZ37093.1 - 3.1e-12 46.7 1.0 8.6e-11 42.0 0.9 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAZ37093.1 - 5.1e-12 46.9 7.4 6.7e-12 46.5 7.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAZ37093.1 - 9.9e-10 38.1 0.0 1.1e-08 34.6 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DLH PF01738.18 AAZ37093.1 - 0.0074 15.9 0.0 0.023 14.2 0.0 1.8 2 0 0 2 2 2 1 Dienelactone hydrolase family Flg_bbr_C PF06429.13 AAZ37094.1 - 2e-13 50.3 10.0 2.1e-13 50.2 6.9 2.4 2 1 0 2 2 2 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 AAZ37094.1 - 1.5e-08 34.4 5.6 4.5e-08 32.8 5.6 1.9 1 0 0 1 1 1 1 Flagella basal body rod protein UPF0029 PF01205.19 AAZ37094.1 - 0.042 14.2 0.3 0.072 13.4 0.1 1.5 2 0 0 2 2 2 0 Uncharacterized protein family UPF0029 CheR PF01739.18 AAZ37095.1 - 8.5e-65 217.9 0.0 1.2e-64 217.4 0.0 1.2 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain CheR_N PF03705.15 AAZ37095.1 - 1.1e-11 44.2 0.0 2.1e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 CheR methyltransferase, all-alpha domain Methyltransf_11 PF08241.12 AAZ37095.1 - 3.9e-06 27.4 0.0 0.00013 22.5 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAZ37095.1 - 1.3e-05 25.8 0.0 0.0001 23.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAZ37095.1 - 1.5e-05 25.6 0.0 0.0011 19.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAZ37095.1 - 0.00035 20.4 0.0 0.0021 17.9 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAZ37095.1 - 0.0096 15.8 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NAS PF03059.16 AAZ37095.1 - 0.09 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Nicotianamine synthase protein DUF218 PF02698.17 AAZ37096.1 - 7.4e-25 87.5 0.0 9.7e-25 87.1 0.0 1.1 1 0 0 1 1 1 1 DUF218 domain Phage_holin_3_6 PF07332.11 AAZ37096.1 - 0.032 14.3 1.8 0.082 12.9 1.8 1.6 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF998 PF06197.13 AAZ37096.1 - 0.9 9.1 9.4 0.057 13.0 4.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF998) AhpC-TSA PF00578.21 AAZ37097.1 - 2.7e-36 124.2 0.2 3.2e-36 124.0 0.2 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AAZ37097.1 - 2.1e-17 63.2 0.1 2.6e-17 62.9 0.1 1.1 1 0 0 1 1 1 1 Redoxin DUF899 PF05988.12 AAZ37097.1 - 8.3e-05 22.2 0.0 9.6e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) AhpC-TSA_2 PF13911.6 AAZ37097.1 - 0.0033 17.5 0.1 0.0094 16.1 0.1 1.7 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme HTH_18 PF12833.7 AAZ37098.1 - 2.4e-19 69.4 1.8 4.4e-19 68.5 0.6 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAZ37098.1 - 4.5e-12 45.7 1.4 5.2e-08 32.8 0.3 2.7 3 0 0 3 3 3 2 Bacterial regulatory helix-turn-helix proteins, AraC family Cupin_2 PF07883.11 AAZ37098.1 - 1e-05 25.1 0.1 2.3e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 AAZ37098.1 - 4.3e-05 23.3 0.7 0.0057 16.4 0.0 2.4 1 1 1 2 2 2 2 Cupin AraC_binding PF02311.19 AAZ37098.1 - 0.00026 20.9 0.6 0.00047 20.1 0.0 1.7 2 0 0 2 2 2 1 AraC-like ligand binding domain HTH_6 PF01418.17 AAZ37098.1 - 0.09 12.8 0.0 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family DUF4124 PF13511.6 AAZ37099.1 - 3.1e-17 62.6 5.7 3.1e-17 62.6 5.7 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4124) DUF4456 PF14644.6 AAZ37099.1 - 0.061 13.0 3.8 0.085 12.5 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) CAF-1_p150 PF11600.8 AAZ37099.1 - 0.079 12.7 7.5 0.12 12.1 7.5 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Aldo_ket_red PF00248.21 AAZ37100.1 - 2.6e-68 230.4 0.0 3e-68 230.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Polysacc_deac_1 PF01522.21 AAZ37101.1 - 2.2e-05 24.3 0.0 6.7e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 Polysaccharide deacetylase Peptidase_C26 PF07722.13 AAZ37102.1 - 5.9e-71 238.7 0.0 6.7e-71 238.5 0.0 1.0 1 0 0 1 1 1 1 Peptidase C26 GATase PF00117.28 AAZ37102.1 - 1.5e-08 34.6 0.0 2.3e-08 34.1 0.0 1.4 1 1 0 1 1 1 1 Glutamine amidotransferase class-I ABC_tran PF00005.27 AAZ37103.1 - 3e-33 115.2 0.0 4.3e-33 114.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAZ37103.1 - 3.3e-08 33.7 0.1 0.0034 17.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AAZ37103.1 - 2.6e-06 27.9 2.9 2.5e-05 24.7 2.9 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AAZ37103.1 - 0.00012 21.8 0.0 0.00027 20.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.12 AAZ37103.1 - 0.00043 20.2 0.0 0.0012 18.7 0.0 1.8 2 0 0 2 2 2 1 NACHT domain RsgA_GTPase PF03193.16 AAZ37103.1 - 0.0006 19.8 0.1 0.0014 18.6 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 AAZ37103.1 - 0.00081 19.0 0.2 0.0029 17.2 0.2 2.0 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 AAZ37103.1 - 0.00089 18.8 0.0 0.33 10.3 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 AAZ37103.1 - 0.00097 19.3 1.3 0.0065 16.6 1.3 2.2 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 AAZ37103.1 - 0.0015 18.8 0.1 0.0039 17.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 AAZ37103.1 - 0.0015 18.8 0.2 0.015 15.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 AAZ37103.1 - 0.005 16.9 0.1 0.03 14.4 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_30 PF13604.6 AAZ37103.1 - 0.005 16.6 0.7 0.014 15.2 0.7 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AAZ37103.1 - 0.0064 17.0 0.0 0.019 15.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 AAZ37103.1 - 0.012 15.4 0.0 0.034 13.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 AAZ37103.1 - 0.017 15.4 0.4 0.17 12.1 0.4 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 AAZ37103.1 - 0.019 14.9 0.1 0.079 13.0 0.1 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) cobW PF02492.19 AAZ37103.1 - 0.033 13.8 0.0 0.065 12.8 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.6 AAZ37103.1 - 0.055 13.8 0.0 0.1 12.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 AAZ37103.1 - 0.089 12.1 1.4 0.24 10.7 0.1 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family IstB_IS21 PF01695.17 AAZ37103.1 - 0.094 12.4 0.2 1.7 8.3 0.0 2.3 2 1 0 2 2 2 0 IstB-like ATP binding protein CbiA PF01656.23 AAZ37103.1 - 0.17 12.0 0.0 2.3 8.3 0.0 2.2 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Dynamin_N PF00350.23 AAZ37103.1 - 0.19 11.8 0.1 0.5 10.4 0.1 1.7 2 0 0 2 2 2 0 Dynamin family AAA_23 PF13476.6 AAZ37103.1 - 0.2 12.1 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 AAZ37103.1 - 0.22 11.2 0.0 3 7.5 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain HTH_31 PF13560.6 AAZ37104.1 - 1.4e-05 25.3 0.1 2.4e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 AAZ37104.1 - 0.0002 21.3 0.1 0.00039 20.4 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix MqsA_antitoxin PF15731.5 AAZ37104.1 - 0.0055 16.8 0.1 0.0082 16.3 0.1 1.2 1 0 0 1 1 1 1 Antitoxin component of bacterial toxin-antitoxin system, MqsA HTH_19 PF12844.7 AAZ37104.1 - 0.079 13.0 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain DXP_reductoisom PF02670.16 AAZ37105.1 - 9.3e-44 149.2 0.1 1.6e-43 148.5 0.1 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXPR_C PF13288.6 AAZ37105.1 - 2e-43 147.3 0.0 3e-43 146.7 0.0 1.3 1 0 0 1 1 1 1 DXP reductoisomerase C-terminal domain DXP_redisom_C PF08436.12 AAZ37105.1 - 2.6e-39 133.3 0.0 5e-39 132.3 0.0 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain GFO_IDH_MocA PF01408.22 AAZ37105.1 - 0.014 16.2 0.1 0.034 15.0 0.0 1.7 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Secretin_N PF03958.17 AAZ37106.1 - 1.5e-10 41.3 0.0 4.4e-10 39.8 0.0 1.8 1 0 0 1 1 1 1 Bacterial type II/III secretion system short domain Secretin PF00263.21 AAZ37106.1 - 2e-06 27.6 2.0 3.3e-06 26.8 2.0 1.3 1 0 0 1 1 1 1 Bacterial type II and III secretion system protein IMD PF08397.11 AAZ37107.1 - 0.024 14.0 6.9 0.035 13.5 6.9 1.3 1 0 0 1 1 1 0 IRSp53/MIM homology domain Miga PF10265.9 AAZ37107.1 - 0.072 12.1 1.2 0.1 11.5 1.2 1.2 1 0 0 1 1 1 0 Mitoguardin BAG PF02179.16 AAZ37107.1 - 0.15 12.5 2.9 0.28 11.6 2.9 1.3 1 0 0 1 1 1 0 BAG domain PDE4_UCR PF18100.1 AAZ37107.1 - 0.23 12.1 0.8 0.81 10.3 0.8 1.9 1 0 0 1 1 1 0 Phosphodiesterase 4 upstream conserved regions (UCR) V-SNARE PF05008.15 AAZ37107.1 - 0.27 11.6 6.3 0.6 10.5 6.3 1.6 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus GrpE PF01025.19 AAZ37107.1 - 0.37 10.4 6.3 0.61 9.7 6.3 1.3 1 0 0 1 1 1 0 GrpE Fib_alpha PF08702.10 AAZ37107.1 - 0.43 10.8 2.2 0.71 10.1 0.3 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CHDCT2 PF08074.11 AAZ37107.1 - 0.7 10.0 3.9 2.4 8.3 3.9 1.9 1 1 0 1 1 1 0 CHDCT2 (NUC038) domain OmpH PF03938.14 AAZ37107.1 - 0.81 10.0 10.6 2.2 8.6 10.6 1.7 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Cob_adeno_trans PF01923.18 AAZ37107.1 - 1.2 9.3 7.9 0.039 14.1 1.8 1.7 2 0 0 2 2 2 0 Cobalamin adenosyltransferase Atg14 PF10186.9 AAZ37107.1 - 1.9 7.5 6.8 2.6 7.1 6.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SBP_bac_3 PF00497.20 AAZ37108.1 - 1.9e-49 168.1 0.0 2.4e-49 167.8 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.7 AAZ37108.1 - 0.00055 19.6 0.1 0.00085 19.0 0.1 1.4 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 AAZ37108.1 - 0.0014 18.7 0.0 0.0019 18.2 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like Lig_chan-Glu_bd PF10613.9 AAZ37108.1 - 0.0017 18.6 0.0 0.044 14.0 0.0 2.3 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SHMT PF00464.19 AAZ37110.1 - 2.5e-183 609.2 0.3 2.9e-183 609.0 0.3 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 AAZ37110.1 - 2.2e-07 30.4 0.0 3.1e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 AAZ37110.1 - 2e-05 24.0 0.2 6.1e-05 22.4 0.2 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 AAZ37110.1 - 5.3e-05 21.9 0.0 6.9e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 AAZ37110.1 - 0.00041 19.8 0.1 0.00056 19.3 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DAGK_cat PF00781.24 AAZ37111.1 - 2.1e-22 79.1 0.1 3.1e-22 78.5 0.1 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 AAZ37111.1 - 0.037 13.2 0.1 0.054 12.7 0.1 1.2 1 0 0 1 1 1 0 ATP-NAD kinase FA_desaturase PF00487.24 AAZ37112.1 - 2.5e-39 135.7 19.0 2.5e-39 135.7 19.0 1.3 1 1 0 1 1 1 1 Fatty acid desaturase MacB_PCD PF12704.7 AAZ37113.1 - 4.1e-37 128.4 1.1 4.1e-37 128.4 1.1 2.4 2 1 0 2 2 1 1 MacB-like periplasmic core domain ABC_tran PF00005.27 AAZ37113.1 - 1.9e-29 102.9 0.0 3.9e-29 101.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsX PF02687.21 AAZ37113.1 - 3.4e-10 40.2 2.4 3.4e-10 40.2 2.4 3.0 3 0 0 3 3 3 1 FtsX-like permease family SMC_N PF02463.19 AAZ37113.1 - 1.3e-05 24.7 0.1 0.054 12.9 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAZ37113.1 - 0.00015 21.4 0.1 0.0021 17.7 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 AAZ37113.1 - 0.0021 17.9 0.2 0.023 14.5 0.0 2.4 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 AAZ37113.1 - 0.0075 15.4 0.1 0.0075 15.4 0.1 2.0 2 0 0 2 2 2 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 AAZ37113.1 - 0.011 15.7 0.1 0.028 14.3 0.1 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 AAZ37113.1 - 0.013 15.9 2.2 0.095 13.1 0.5 2.7 2 1 1 3 3 3 0 AAA ATPase domain AAA_28 PF13521.6 AAZ37113.1 - 0.019 15.2 0.2 0.075 13.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 AAZ37113.1 - 0.019 15.0 0.1 0.045 13.8 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 AAZ37113.1 - 0.052 13.7 0.3 0.87 9.7 0.3 2.5 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 AAZ37113.1 - 0.066 12.6 0.1 0.18 11.1 0.1 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_23 PF13476.6 AAZ37113.1 - 0.089 13.3 0.3 0.28 11.7 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 AAZ37113.1 - 0.096 13.0 0.2 0.45 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 AAZ37113.1 - 0.15 12.1 0.8 0.33 11.0 0.2 1.8 2 0 0 2 2 2 0 Helicase HerA, central domain DUF4064 PF13273.6 AAZ37113.1 - 1.8 8.9 15.6 28 5.1 11.2 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) AAA_30 PF13604.6 AAZ37113.1 - 5 6.8 12.0 1.7 8.4 0.0 4.0 5 0 0 5 5 5 0 AAA domain BPD_transp_1 PF00528.22 AAZ37114.1 - 1.2e-22 80.6 17.7 1.2e-22 80.6 17.7 1.6 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component GGDEF PF00990.21 AAZ37116.1 - 1.8e-39 135.1 1.2 4.8e-39 133.7 0.0 2.4 4 0 0 4 4 4 1 Diguanylate cyclase, GGDEF domain Response_reg PF00072.24 AAZ37116.1 - 3.1e-32 111.1 0.4 2.2e-23 82.5 0.2 3.3 2 1 1 3 3 3 2 Response regulator receiver domain FleQ PF06490.11 AAZ37116.1 - 0.0015 18.9 0.1 0.073 13.4 0.0 2.7 2 1 0 2 2 2 1 Flagellar regulatory protein FleQ FeoA PF04023.14 AAZ37116.1 - 0.15 12.3 0.1 0.37 11.1 0.1 1.7 1 0 0 1 1 1 0 FeoA domain Phage_ABA_S PF18066.1 AAZ37116.1 - 0.16 12.6 0.0 0.42 11.3 0.0 1.7 1 0 0 1 1 1 0 Phage ABA sandwich domain Aldedh PF00171.22 AAZ37117.1 - 6.3e-115 384.3 0.1 1e-114 383.6 0.1 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pro_dh PF01619.18 AAZ37117.1 - 8.9e-102 340.6 0.0 1.7e-101 339.7 0.0 1.5 1 0 0 1 1 1 1 Proline dehydrogenase Pro_dh-DNA_bdg PF14850.6 AAZ37117.1 - 3.7e-45 153.0 0.0 9.8e-45 151.7 0.0 1.8 1 0 0 1 1 1 1 DNA-binding domain of Proline dehydrogenase PRODH PF18327.1 AAZ37117.1 - 4.7e-16 58.7 3.7 4.7e-16 58.7 3.7 3.9 4 0 0 4 4 4 1 Proline utilization A proline dehydrogenase N-terminal domain RQC PF09382.10 AAZ37118.1 - 1e-36 125.2 0.0 1.9e-36 124.3 0.0 1.5 1 0 0 1 1 1 1 RQC domain HRDC PF00570.23 AAZ37118.1 - 2.1e-21 75.7 0.1 4.5e-21 74.6 0.1 1.6 1 0 0 1 1 1 1 HRDC domain Helicase_C PF00271.31 AAZ37118.1 - 1.2e-20 73.9 0.0 9.4e-17 61.4 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 AAZ37118.1 - 6e-20 71.7 4.2 1.4e-19 70.6 4.2 1.7 1 0 0 1 1 1 1 RecQ zinc-binding DEAD PF00270.29 AAZ37118.1 - 7.4e-18 64.9 0.0 1.2e-17 64.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase HTH_40 PF14493.6 AAZ37118.1 - 0.0027 18.1 0.0 0.0071 16.8 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain GerE PF00196.19 AAZ37118.1 - 0.02 14.4 0.0 0.044 13.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_29 PF13551.6 AAZ37118.1 - 0.031 14.3 0.0 0.24 11.4 0.0 2.6 2 0 0 2 2 2 0 Winged helix-turn helix IF2_N PF04760.15 AAZ37118.1 - 0.071 12.9 0.0 9.6 6.1 0.0 2.6 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region Sigma70_r4_2 PF08281.12 AAZ37118.1 - 0.11 12.3 0.0 0.38 10.5 0.0 2.0 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_23 PF13384.6 AAZ37118.1 - 0.11 12.4 0.0 0.11 12.4 0.0 2.7 3 0 0 3 3 3 0 Homeodomain-like domain CobA_CobO_BtuR PF02572.15 AAZ37119.1 - 2.3e-55 187.5 0.0 2.8e-55 187.2 0.0 1.1 1 0 0 1 1 1 1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Co_AT_N PF12557.8 AAZ37119.1 - 1.7e-05 24.6 0.9 3.2e-05 23.7 0.9 1.5 1 0 0 1 1 1 1 Cob(I)alamin adenosyltransferase N terminal Aminotran_1_2 PF00155.21 AAZ37120.1 - 7e-80 268.9 0.0 8e-80 268.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Biotin_lipoyl PF00364.22 AAZ37121.1 - 1e-05 25.3 0.0 1.5e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 AAZ37121.1 - 0.00098 18.9 0.0 0.28 11.1 0.0 2.4 2 0 0 2 2 2 2 Biotin-lipoyl like RnfC_N PF13375.6 AAZ37121.1 - 0.018 14.9 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain tRNA-synt_1c PF00749.21 AAZ37123.1 - 1.3e-45 155.7 0.0 1.3e-27 96.6 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain ABC_tran PF00005.27 AAZ37125.1 - 2.1e-32 112.5 0.0 2.7e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAZ37125.1 - 4.2e-07 30.1 2.3 0.013 15.3 0.7 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAZ37125.1 - 1.7e-06 27.7 0.0 0.0011 18.4 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAZ37125.1 - 0.00016 21.3 0.5 0.00035 20.3 0.5 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AAZ37125.1 - 0.0019 18.1 0.2 0.0034 17.3 0.2 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 AAZ37125.1 - 0.0025 18.2 1.7 0.005 17.2 1.7 1.6 1 1 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.23 AAZ37125.1 - 0.0076 16.3 0.1 0.0085 16.2 0.1 1.3 1 1 0 1 1 1 1 Dynamin family AAA_18 PF13238.6 AAZ37125.1 - 0.011 16.3 1.1 0.092 13.3 1.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 AAZ37125.1 - 0.018 15.3 0.5 0.055 13.7 0.5 1.9 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AAZ37125.1 - 0.034 14.4 2.0 0.4 11.0 1.9 2.2 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.17 AAZ37125.1 - 0.044 13.9 0.3 0.093 12.8 0.3 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 AAZ37125.1 - 0.053 12.9 0.1 0.093 12.1 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_23 PF13476.6 AAZ37125.1 - 0.098 13.1 1.3 0.14 12.6 0.1 1.8 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 AAZ37125.1 - 0.14 12.3 0.6 0.42 10.7 0.5 1.8 1 1 1 2 2 2 0 50S ribosome-binding GTPase Metallophos_3 PF14582.6 AAZ37125.1 - 0.16 11.2 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily NACHT PF05729.12 AAZ37125.1 - 0.17 11.8 1.2 0.31 11.0 0.5 1.7 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.6 AAZ37125.1 - 0.4 10.8 1.6 0.9 9.7 1.6 1.9 1 1 0 1 1 1 0 AAA domain Y2_Tnp PF04986.13 AAZ37126.1 - 5.4e-47 160.2 1.9 9.5e-47 159.4 1.9 1.4 1 0 0 1 1 1 1 Putative transposase Zn_Tnp_IS91 PF14319.6 AAZ37126.1 - 1.4e-22 79.6 7.3 2.7e-22 78.6 7.3 1.5 1 0 0 1 1 1 1 Transposase zinc-binding domain zf-B_box PF00643.24 AAZ37126.1 - 0.16 12.2 12.7 0.39 10.9 12.7 1.7 1 0 0 1 1 1 0 B-box zinc finger RHS_repeat PF05593.14 AAZ37127.1 - 0.23 12.0 0.9 6.1 7.5 0.0 3.0 3 0 0 3 3 3 0 RHS Repeat FecCD PF01032.18 AAZ37128.1 - 1.3e-87 293.8 34.6 1.6e-87 293.5 34.6 1.0 1 0 0 1 1 1 1 FecCD transport family OpuAC PF04069.12 AAZ37129.1 - 2.9e-55 187.6 1.6 3.4e-55 187.4 1.6 1.0 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system DUF3053 PF11254.8 AAZ37130.1 - 1.7e-75 253.4 0.5 1.9e-75 253.2 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3053) BPD_transp_2 PF02653.16 AAZ37131.1 - 1.9e-42 145.3 36.7 3e-42 144.6 36.7 1.3 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component PALP PF00291.25 AAZ37132.1 - 1.7e-84 283.7 2.9 2.1e-84 283.4 2.9 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 AAZ37132.1 - 8.2e-47 156.9 0.0 5.9e-26 90.1 0.0 2.4 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase DUF3335 PF11814.8 AAZ37132.1 - 0.11 11.9 0.1 0.21 11.0 0.1 1.4 1 0 0 1 1 1 0 Peptidase_C39 like family TMP_2 PF06791.13 AAZ37132.1 - 0.17 11.6 1.9 0.52 10.0 0.9 2.1 2 0 0 2 2 2 0 Prophage tail length tape measure protein MreB_Mbl PF06723.13 AAZ37135.1 - 5.9e-149 495.3 2.3 6.8e-149 495.1 2.3 1.0 1 0 0 1 1 1 1 MreB/Mbl protein HSP70 PF00012.20 AAZ37135.1 - 6.8e-14 51.0 0.5 4.3e-13 48.3 0.1 2.3 1 1 1 2 2 2 1 Hsp70 protein Actin PF00022.19 AAZ37135.1 - 2e-11 43.1 0.0 7.6e-08 31.4 0.0 2.1 1 1 0 2 2 2 2 Actin FtsA PF14450.6 AAZ37135.1 - 9.1e-11 42.1 0.7 1.3e-09 38.4 0.1 2.4 2 0 0 2 2 2 1 Cell division protein FtsA PilM_2 PF11104.8 AAZ37135.1 - 1e-06 28.0 0.0 0.02 14.0 0.0 2.2 1 1 1 2 2 2 2 Type IV pilus assembly protein PilM; Ppx-GppA PF02541.16 AAZ37135.1 - 0.00028 20.4 2.5 0.00041 19.9 0.3 2.1 2 1 0 3 3 3 1 Ppx/GppA phosphatase family EutA PF06277.11 AAZ37135.1 - 0.0062 15.4 1.1 0.018 13.9 0.5 1.9 1 1 1 2 2 2 1 Ethanolamine utilisation protein EutA DDR PF08841.10 AAZ37135.1 - 0.009 15.0 0.5 0.03 13.3 0.2 1.9 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.16 AAZ37135.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain PriA_3primeBD PF17764.1 AAZ37136.1 - 1.2e-25 89.2 0.0 2.6e-25 88.2 0.0 1.6 1 0 0 1 1 1 1 3′ DNA-binding domain (3′BD) PriA_C PF18074.1 AAZ37136.1 - 8.2e-25 87.5 0.0 4.4e-24 85.1 0.0 2.3 3 0 0 3 3 3 1 Primosomal protein N C-terminal domain DEAD PF00270.29 AAZ37136.1 - 2.5e-15 56.7 0.0 3.8e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 AAZ37136.1 - 5.5e-14 52.5 0.0 8.7e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 AAZ37136.1 - 2.8e-11 43.8 0.0 0.00017 21.9 0.0 2.8 3 0 0 3 3 3 2 Helicase conserved C-terminal domain PriA_CRR PF18319.1 AAZ37136.1 - 2.9e-11 43.1 7.1 2.9e-11 43.1 7.1 2.8 3 0 0 3 3 2 1 PriA DNA helicase Cys-rich region (CRR) domain HypA PF01155.19 AAZ37136.1 - 0.0035 17.4 1.8 0.009 16.0 1.8 1.7 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TrwB_AAD_bind PF10412.9 AAZ37136.1 - 0.015 14.3 0.0 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 AAZ37136.1 - 0.016 14.9 0.0 0.046 13.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.14 AAZ37136.1 - 0.064 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase zinc-ribbons_6 PF07191.12 AAZ37136.1 - 0.085 12.8 4.9 0.19 11.8 4.9 1.5 1 0 0 1 1 1 0 zinc-ribbons cobW PF02492.19 AAZ37136.1 - 0.089 12.4 0.0 4 7.0 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 AAZ37136.1 - 0.21 10.8 0.0 0.38 10.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin TF_Zn_Ribbon PF08271.12 AAZ37136.1 - 3.8 7.1 7.0 2 8.0 0.3 2.9 2 1 1 3 3 3 0 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 AAZ37136.1 - 8.3 6.6 12.2 61 3.9 8.5 2.9 2 1 0 2 2 2 0 Zinc ribbon domain THF_DHG_CYH_C PF02882.19 AAZ37137.1 - 2.2e-66 222.1 0.1 3e-66 221.6 0.1 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 AAZ37137.1 - 6.3e-39 132.8 0.0 8.6e-39 132.4 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 AAZ37137.1 - 0.016 14.2 0.1 0.024 13.6 0.1 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family TetR_N PF00440.23 AAZ37138.1 - 4.8e-16 58.3 0.1 9.8e-16 57.3 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_33 PF13305.6 AAZ37138.1 - 4.9e-08 33.7 0.1 9.8e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain HTH_40 PF14493.6 AAZ37138.1 - 0.032 14.7 0.0 0.055 13.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_11 PF08279.12 AAZ37138.1 - 0.15 12.1 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 HTH domain DUF45 PF01863.17 AAZ37139.1 - 1.4e-12 48.1 1.5 1.7e-12 47.8 1.5 1.4 1 1 0 1 1 1 1 Protein of unknown function DUF45 WLM PF08325.10 AAZ37139.1 - 2.4e-05 24.5 0.5 3.9e-05 23.8 0.5 1.4 1 0 0 1 1 1 1 WLM domain Peptidase_M56 PF05569.11 AAZ37139.1 - 0.071 12.3 0.5 0.092 11.9 0.1 1.3 2 0 0 2 2 2 0 BlaR1 peptidase M56 Glycos_transf_2 PF00535.26 AAZ37140.1 - 6.9e-16 58.5 0.0 9.1e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 NMO PF03060.15 AAZ37141.1 - 1.2e-44 153.0 5.6 3.4e-32 112.2 1.7 2.2 1 1 1 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 AAZ37141.1 - 3.1e-10 39.6 9.8 5.3e-10 38.9 6.7 2.2 1 1 0 2 2 2 1 FMN-dependent dehydrogenase IMPDH PF00478.25 AAZ37141.1 - 8.8e-09 34.8 3.3 0.0024 16.9 0.0 2.4 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain DUF1729 PF08354.10 AAZ37141.1 - 0.00066 18.7 0.3 0.0021 17.0 0.3 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1729) DHO_dh PF01180.21 AAZ37141.1 - 0.094 11.9 0.3 0.22 10.7 0.2 1.5 1 1 1 2 2 2 0 Dihydroorotate dehydrogenase Glu_synthase PF01645.17 AAZ37141.1 - 0.65 9.1 5.6 1.8 7.6 5.6 1.7 1 1 0 1 1 1 0 Conserved region in glutamate synthase MarB PF13999.6 AAZ37142.1 - 0.064 13.1 0.2 0.11 12.4 0.2 1.5 1 1 0 1 1 1 0 MarB protein Gcw_chp PF09694.10 AAZ37143.1 - 1e-14 55.1 1.4 2.1e-14 54.1 1.4 1.7 1 1 0 1 1 1 1 Bacterial protein of unknown function (Gcw_chp) Phasin PF05597.11 AAZ37144.1 - 2.4e-37 127.8 0.6 3.3e-37 127.3 0.6 1.2 1 0 0 1 1 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) Transcrip_act PF04949.13 AAZ37144.1 - 0.0019 18.1 0.6 0.01 15.7 0.8 1.9 1 1 1 2 2 2 1 Transcriptional activator DUF677 PF05055.12 AAZ37144.1 - 0.042 12.7 0.1 0.058 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) DUF4083 PF13314.6 AAZ37144.1 - 0.55 10.2 2.2 1.1 9.3 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4083) PilM PF07419.12 AAZ37145.1 - 2.8e-44 150.5 0.2 3.2e-44 150.4 0.2 1.0 1 0 0 1 1 1 1 PilM HATPase_c PF02518.26 AAZ37146.1 - 9.4e-19 68.0 0.0 7.1e-18 65.1 0.0 2.3 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAZ37146.1 - 1.5e-13 50.5 0.2 1.5e-13 50.5 0.2 3.6 4 1 0 4 4 4 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 AAZ37146.1 - 4.6e-07 30.5 0.2 1.4e-06 29.0 0.0 1.9 2 0 0 2 2 2 1 GAF domain GAF_2 PF13185.6 AAZ37146.1 - 0.0011 19.3 0.0 0.014 15.7 0.0 2.6 3 0 0 3 3 3 1 GAF domain GAF_3 PF13492.6 AAZ37146.1 - 0.0017 18.7 0.0 0.0058 17.0 0.0 2.0 2 0 0 2 2 2 1 GAF domain HATPase_c_2 PF13581.6 AAZ37146.1 - 0.0066 16.4 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain Usher PF00577.20 AAZ37147.1 - 3.8e-161 537.7 9.0 4.6e-161 537.4 9.0 1.0 1 0 0 1 1 1 1 Outer membrane usher protein PapC_N PF13954.6 AAZ37147.1 - 1.7e-41 141.6 0.0 1.3e-40 138.7 0.0 2.5 3 0 0 3 3 3 1 PapC N-terminal domain PapC_C PF13953.6 AAZ37147.1 - 1.8e-14 53.3 0.0 4.5e-14 52.0 0.0 1.8 1 0 0 1 1 1 1 PapC C-terminal domain Big_6 PF17936.1 AAZ37147.1 - 0.0064 16.7 0.1 0.031 14.5 0.0 2.2 2 0 0 2 2 2 1 Bacterial Ig domain ATP_bind_2 PF03668.15 AAZ37148.1 - 5e-92 308.2 0.0 5.6e-92 308.0 0.0 1.0 1 0 0 1 1 1 1 P-loop ATPase protein family AAA_18 PF13238.6 AAZ37148.1 - 0.00031 21.3 0.3 0.0072 16.9 0.3 2.5 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAZ37148.1 - 0.0043 16.8 0.1 0.0078 15.9 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.6 AAZ37148.1 - 0.0093 16.1 0.2 1.2 9.3 0.0 2.3 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AAZ37148.1 - 0.038 14.4 0.1 0.074 13.4 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 AAZ37148.1 - 0.14 11.2 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.6 AAZ37148.1 - 0.16 12.2 0.0 0.65 10.2 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.6 AAZ37148.1 - 0.17 12.2 0.3 0.43 10.8 0.2 1.9 1 1 0 1 1 1 0 AAA domain TerD PF02342.18 AAZ37149.1 - 2e-84 281.7 0.0 2.2e-84 281.6 0.0 1.0 1 0 0 1 1 1 1 TerD domain QSregVF PF13652.6 AAZ37150.1 - 2.9e-64 214.1 0.4 3.4e-64 213.9 0.4 1.0 1 0 0 1 1 1 1 Putative quorum-sensing-regulated virulence factor Beta-lactamase PF00144.24 AAZ37151.1 - 8.9e-35 120.5 4.4 1.2e-34 120.1 4.4 1.1 1 0 0 1 1 1 1 Beta-lactamase MCPsignal PF00015.21 AAZ37152.1 - 7.7e-43 146.3 34.6 1.1e-42 145.7 25.1 2.8 1 1 1 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain dCache_2 PF08269.11 AAZ37152.1 - 5.7e-39 134.1 0.0 5.7e-39 134.1 0.0 2.9 2 1 1 3 3 3 1 Cache domain sCache_2 PF17200.4 AAZ37152.1 - 1.4e-38 132.2 0.1 1.4e-38 132.2 0.1 2.6 2 0 0 2 2 2 1 Single Cache domain 2 HAMP PF00672.25 AAZ37152.1 - 4.1e-14 52.7 1.6 2.3e-13 50.3 0.1 3.2 3 0 0 3 3 3 1 HAMP domain Cache_3-Cache_2 PF17201.4 AAZ37152.1 - 9e-12 44.9 0.0 9e-12 44.9 0.0 3.1 3 1 1 4 4 4 1 Cache 3/Cache 2 fusion domain DUF4492 PF14899.6 AAZ37152.1 - 0.0082 16.0 0.2 0.0082 16.0 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4492) CaKB PF03185.15 AAZ37152.1 - 0.07 12.8 2.1 0.086 12.5 0.0 2.1 2 0 0 2 2 2 0 Calcium-activated potassium channel, beta subunit DUF494 PF04361.13 AAZ37152.1 - 0.13 12.2 1.8 2 8.3 0.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF494) DUF4083 PF13314.6 AAZ37152.1 - 0.64 10.0 4.9 15 5.6 1.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) DUF3958 PF13125.6 AAZ37152.1 - 1.4 9.2 6.4 0.32 11.2 0.5 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3958) DUF4200 PF13863.6 AAZ37152.1 - 4 7.9 7.5 2.9 8.3 0.4 3.3 2 2 1 3 3 3 0 Domain of unknown function (DUF4200) ISG65-75 PF11727.8 AAZ37152.1 - 9 5.4 11.5 0.66 9.2 1.3 2.4 2 0 0 2 2 2 0 Invariant surface glycoprotein HATPase_c PF02518.26 AAZ37153.1 - 2.8e-19 69.7 0.0 5.3e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAZ37153.1 - 1.8e-10 40.7 0.1 9.2e-10 38.4 0.0 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 AAZ37153.1 - 1.2e-09 38.3 0.0 2.2e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c_2 PF13581.6 AAZ37153.1 - 8.9e-05 22.4 0.0 0.0002 21.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain Exo_endo_phos PF03372.23 AAZ37154.1 - 1.8e-14 53.8 0.4 2.4e-14 53.4 0.4 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 AAZ37154.1 - 0.066 13.1 0.0 0.48 10.3 0.0 2.2 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase Glycos_transf_1 PF00534.20 AAZ37155.1 - 2.3e-22 79.3 0.0 3.6e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAZ37155.1 - 2.8e-18 66.7 0.1 5.1e-18 65.8 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAZ37155.1 - 2.1e-09 37.6 0.1 4.6e-09 36.5 0.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 HU-CCDC81_bac_1 PF18174.1 AAZ37155.1 - 0.058 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 1 ABC_tran PF00005.27 AAZ37156.1 - 6.8e-35 120.6 0.0 9.3e-35 120.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAZ37156.1 - 9.1e-09 35.5 0.0 0.0019 18.1 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAZ37156.1 - 8.6e-08 31.9 0.2 4.8e-07 29.4 0.2 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AAZ37156.1 - 0.00015 22.2 0.1 0.00025 21.5 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AAZ37156.1 - 0.00015 21.4 0.0 0.0003 20.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AAZ37156.1 - 0.0003 20.7 0.1 0.00063 19.7 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 AAZ37156.1 - 0.00032 21.0 0.3 0.00099 19.4 0.3 2.0 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 AAZ37156.1 - 0.00056 20.5 0.0 0.00097 19.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AAZ37156.1 - 0.0013 18.9 0.4 0.0036 17.5 0.2 1.7 2 1 0 2 2 2 1 AAA domain Rad17 PF03215.15 AAZ37156.1 - 0.0017 18.3 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_15 PF13175.6 AAZ37156.1 - 0.0018 18.0 0.0 0.033 13.9 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain ABC_ATPase PF09818.9 AAZ37156.1 - 0.0074 15.1 0.2 2.4 6.9 0.1 2.9 2 1 0 2 2 2 1 Predicted ATPase of the ABC class SbcCD_C PF13558.6 AAZ37156.1 - 0.011 15.9 0.3 0.44 10.8 0.3 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RNA12 PF10443.9 AAZ37156.1 - 0.013 14.3 0.0 0.018 13.8 0.0 1.2 1 0 0 1 1 1 0 RNA12 protein ATPase_2 PF01637.18 AAZ37156.1 - 0.013 15.4 0.1 0.048 13.6 0.0 1.9 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_13 PF13166.6 AAZ37156.1 - 0.014 14.0 0.0 0.94 8.0 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 AAZ37156.1 - 0.015 15.8 0.0 0.025 15.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AAZ37156.1 - 0.019 14.7 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 AAZ37156.1 - 0.021 15.2 0.3 0.35 11.3 0.3 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 AAZ37156.1 - 0.03 13.7 0.2 0.18 11.2 0.0 2.0 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.23 AAZ37156.1 - 0.033 14.3 0.3 0.39 10.8 0.3 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase DLIC PF05783.11 AAZ37156.1 - 0.053 12.3 0.0 0.077 11.8 0.0 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) T2SSE PF00437.20 AAZ37156.1 - 0.056 12.5 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 AAZ37156.1 - 0.057 13.1 0.1 0.21 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 AAZ37156.1 - 0.093 12.6 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 NTPase AAA_25 PF13481.6 AAZ37156.1 - 0.097 12.2 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 AAZ37156.1 - 0.11 12.9 0.1 0.44 11.0 0.0 2.0 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.17 AAZ37156.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 AAZ37156.1 - 0.12 12.6 0.1 0.49 10.6 0.1 2.3 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 AAZ37156.1 - 0.16 11.2 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin PfkB PF00294.24 AAZ37157.1 - 1.9e-55 188.3 0.0 2.3e-55 188.0 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Peptidase_M20 PF01546.28 AAZ37158.1 - 1.4e-34 119.6 0.7 3.9e-34 118.2 0.7 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AAZ37158.1 - 5.6e-12 45.6 0.0 1.2e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain BenE PF03594.13 AAZ37160.1 - 3.1e-153 510.0 41.2 3.6e-153 509.8 41.2 1.0 1 0 0 1 1 1 1 Benzoate membrane transport protein DUF4223 PF13978.6 AAZ37160.1 - 0.83 9.7 3.4 1.5 8.8 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4223) FCD PF07729.12 AAZ37161.1 - 1.5e-15 57.8 9.5 2.2e-15 57.2 9.5 1.2 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 AAZ37161.1 - 2.7e-07 30.1 2.3 4.3e-07 29.5 0.0 2.5 3 1 1 4 4 4 1 Bacterial regulatory proteins, gntR family Lactamase_B_2 PF12706.7 AAZ37162.1 - 8.9e-46 155.9 0.4 1.5e-45 155.2 0.4 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 AAZ37162.1 - 9.5e-13 48.4 0.0 1.2e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 AAZ37162.1 - 0.0001 22.4 0.2 0.01 15.9 0.1 2.3 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Ribonucleas_3_3 PF14622.6 AAZ37163.1 - 1.5e-36 125.4 0.0 2e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 AAZ37163.1 - 6.4e-22 78.2 0.0 1.3e-21 77.2 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.26 AAZ37163.1 - 2.1e-08 34.7 0.0 2.9e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Double-stranded RNA binding motif LPG_synthase_TM PF03706.13 AAZ37164.1 - 4.2e-43 148.0 39.0 5.3e-43 147.7 39.0 1.0 1 0 0 1 1 1 1 Lysylphosphatidylglycerol synthase TM region MS_channel PF00924.18 AAZ37164.1 - 8.9 5.8 9.6 8.6 5.8 3.7 2.5 2 1 0 2 2 2 0 Mechanosensitive ion channel Baculo_PEP_C PF04513.12 AAZ37165.1 - 1.3e-06 28.5 2.1 2.1e-06 27.8 2.1 1.3 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus FlxA PF14282.6 AAZ37165.1 - 0.00069 19.6 5.9 0.00069 19.6 5.9 2.3 1 1 1 2 2 2 1 FlxA-like protein P16-Arc PF04699.14 AAZ37165.1 - 0.0014 19.1 3.3 0.0019 18.7 3.1 1.3 1 1 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) HIP1_clath_bdg PF16515.5 AAZ37165.1 - 0.0034 17.9 2.9 0.0075 16.9 2.9 1.5 1 0 0 1 1 1 1 Clathrin-binding domain of Huntingtin-interacting protein 1 ING PF12998.7 AAZ37165.1 - 0.0038 17.8 0.4 0.0075 16.8 0.4 1.4 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding FapA PF03961.13 AAZ37165.1 - 0.0045 15.7 2.0 0.0049 15.5 2.0 1.0 1 0 0 1 1 1 1 Flagellar Assembly Protein A CCDC-167 PF15188.6 AAZ37165.1 - 0.022 15.1 1.0 0.037 14.4 1.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 TBCC_N PF16752.5 AAZ37165.1 - 0.028 14.9 2.1 0.046 14.2 2.1 1.4 1 0 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain Phage_GPO PF05929.11 AAZ37165.1 - 0.03 14.0 5.0 0.037 13.6 5.0 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase SKA2 PF16740.5 AAZ37165.1 - 0.03 14.1 1.5 0.047 13.5 1.5 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 FliT PF05400.13 AAZ37165.1 - 0.036 14.9 5.4 0.085 13.7 4.6 1.9 1 1 1 2 2 2 0 Flagellar protein FliT CLZ PF16526.5 AAZ37165.1 - 0.07 13.5 2.9 2 8.8 0.2 2.3 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ZapB PF06005.12 AAZ37165.1 - 0.09 13.2 3.4 0.22 12.0 3.4 1.6 1 1 0 1 1 1 0 Cell division protein ZapB Syntaxin_2 PF14523.6 AAZ37165.1 - 0.12 12.8 5.0 1.8 9.0 1.6 2.1 1 1 1 2 2 2 0 Syntaxin-like protein ABC_tran_CTD PF16326.5 AAZ37165.1 - 0.12 12.6 2.7 0.43 10.8 2.6 2.0 1 1 0 1 1 1 0 ABC transporter C-terminal domain Allexi_40kDa PF05549.11 AAZ37165.1 - 0.16 11.5 2.3 0.21 11.1 1.8 1.3 1 1 0 1 1 1 0 Allexivirus 40kDa protein DUF2203 PF09969.9 AAZ37165.1 - 0.41 11.4 2.9 0.66 10.7 1.6 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) COG2 PF06148.11 AAZ37165.1 - 0.44 10.6 2.4 2.3 8.3 1.4 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1690 PF07956.11 AAZ37165.1 - 0.53 10.7 4.9 0.68 10.4 4.4 1.5 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) FAM76 PF16046.5 AAZ37165.1 - 0.95 8.8 3.5 1.2 8.5 3.5 1.0 1 0 0 1 1 1 0 FAM76 protein Cytochrom_B562 PF07361.11 AAZ37165.1 - 1.1 9.9 5.2 0.66 10.7 1.8 2.0 1 1 1 2 2 2 0 Cytochrome b562 Uso1_p115_C PF04871.13 AAZ37165.1 - 9 6.7 8.5 1.4e+02 2.8 8.1 2.0 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF1654 PF07867.11 AAZ37166.1 - 4e-27 93.8 2.2 4.4e-27 93.6 2.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1654) Cupin_3 PF05899.12 AAZ37167.1 - 3e-11 42.9 0.1 3.6e-08 33.0 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_6 PF12852.7 AAZ37167.1 - 2.6e-05 24.0 0.1 0.037 13.7 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 AAZ37167.1 - 5.5e-05 22.8 0.0 0.071 12.8 0.0 2.2 2 0 0 2 2 2 2 Cupin domain AraC_binding_2 PF14525.6 AAZ37167.1 - 0.03 14.0 0.3 0.75 9.5 0.2 2.1 2 0 0 2 2 2 0 AraC-binding-like domain AraC_binding PF02311.19 AAZ37167.1 - 0.042 13.7 0.0 5.7 6.8 0.0 2.2 2 0 0 2 2 2 0 AraC-like ligand binding domain EutQ PF06249.12 AAZ37167.1 - 0.058 13.1 0.0 1.1 9.0 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation protein EutQ HgmA PF04209.13 AAZ37167.1 - 0.12 11.0 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 homogentisate 1,2-dioxygenase Rubredoxin PF00301.20 AAZ37168.1 - 3.7e-22 78.1 3.9 4.1e-22 77.9 3.9 1.0 1 0 0 1 1 1 1 Rubredoxin zf-RanBP PF00641.18 AAZ37168.1 - 0.00013 21.2 4.5 0.02 14.2 0.4 2.1 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others zf-C2H2_3 PF13878.6 AAZ37168.1 - 0.013 15.3 0.0 0.23 11.3 0.0 2.1 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO ADK_lid PF05191.14 AAZ37168.1 - 0.019 14.9 0.2 0.043 13.8 0.2 1.5 1 1 0 1 1 1 0 Adenylate kinase, active site lid DUF1936 PF09151.10 AAZ37168.1 - 0.11 12.4 1.2 0.16 11.9 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) PHD_4 PF16866.5 AAZ37168.1 - 0.73 10.0 6.7 6 7.0 5.7 2.0 1 1 0 1 1 1 0 PHD-finger Vps36-NZF-N PF16988.5 AAZ37168.1 - 3 7.3 6.2 25 4.3 6.2 2.1 1 1 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Exo_endo_phos PF03372.23 AAZ37169.1 - 5.7e-15 55.5 0.5 7.5e-15 55.1 0.5 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family YlbE PF14003.6 AAZ37169.1 - 0.19 12.2 0.0 0.41 11.1 0.0 1.5 1 0 0 1 1 1 0 YlbE-like protein TauD PF02668.16 AAZ37170.1 - 1.7e-65 221.5 3.4 1.9e-65 221.3 3.4 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Abhydrolase_9 PF10081.9 AAZ37170.1 - 0.012 14.8 0.3 0.04 13.0 0.0 1.9 2 1 0 3 3 3 0 Alpha/beta-hydrolase family MFS_1 PF07690.16 AAZ37171.1 - 7.9e-24 84.2 62.9 7.7e-23 81.0 48.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 AAZ37171.1 - 0.00027 19.6 10.3 0.00027 19.6 10.3 2.8 2 1 1 3 3 3 2 MFS/sugar transport protein DUF2530 PF10745.9 AAZ37171.1 - 0.0022 18.2 2.2 0.0022 18.2 2.2 4.0 4 1 0 4 4 4 1 Protein of unknown function (DUF2530) MFS_1_like PF12832.7 AAZ37171.1 - 0.0044 15.9 0.2 0.0044 15.9 0.2 3.0 3 0 0 3 3 3 1 MFS_1 like family YhcG_C PF06250.11 AAZ37172.1 - 1.2e-54 184.3 0.0 1.8e-54 183.8 0.0 1.2 1 0 0 1 1 1 1 YhcG PDDEXK nuclease domain DUF1016_N PF17761.1 AAZ37172.1 - 3.4e-46 156.8 0.9 4.9e-46 156.3 0.9 1.2 1 0 0 1 1 1 1 DUF1016 N-terminal domain HTH_ParB PF17762.1 AAZ37172.1 - 0.037 13.8 0.1 0.087 12.6 0.1 1.6 1 0 0 1 1 1 0 HTH domain found in ParB protein Bac_DnaA PF00308.18 AAZ37173.1 - 7.8e-101 336.5 0.2 1.3e-100 335.8 0.2 1.3 1 0 0 1 1 1 1 Bacterial dnaA protein Bac_DnaA_C PF08299.11 AAZ37173.1 - 4.1e-32 110.0 0.1 9.8e-32 108.8 0.1 1.7 1 0 0 1 1 1 1 Bacterial dnaA protein helix-turn-helix DnaA_N PF11638.8 AAZ37173.1 - 1.3e-21 76.1 0.1 3.3e-21 74.8 0.1 1.8 1 0 0 1 1 1 1 DnaA N-terminal domain IstB_IS21 PF01695.17 AAZ37173.1 - 2.4e-08 33.9 0.0 4e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA PF00004.29 AAZ37173.1 - 3.2e-06 27.6 0.0 1.5e-05 25.4 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AFG1_ATPase PF03969.16 AAZ37173.1 - 6e-05 22.1 0.2 0.00018 20.5 0.2 1.9 1 1 0 1 1 1 1 AFG1-like ATPase Kinesin PF00225.23 AAZ37173.1 - 0.00046 19.2 0.0 0.0018 17.2 0.0 1.9 1 1 0 1 1 1 1 Kinesin motor domain ATPase_2 PF01637.18 AAZ37173.1 - 0.0025 17.8 0.2 0.018 15.0 0.0 2.1 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 AAZ37173.1 - 0.0031 17.6 0.1 0.011 15.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 AAZ37173.1 - 0.01 16.1 2.0 0.24 11.6 0.3 3.1 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 AAZ37173.1 - 0.02 15.3 0.4 0.12 12.8 0.1 2.6 2 1 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.6 AAZ37173.1 - 0.13 12.6 0.0 0.29 11.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain DNA_pol3_a_NII PF11490.8 AAZ37173.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II RNA_helicase PF00910.22 AAZ37173.1 - 0.15 12.5 0.0 0.36 11.3 0.0 1.7 1 1 0 1 1 1 0 RNA helicase SKI PF01202.22 AAZ37174.1 - 9.2e-07 29.1 0.0 1e-06 28.9 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 AAZ37174.1 - 0.00027 21.1 0.0 0.00037 20.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAZ37174.1 - 0.0011 19.4 0.0 0.0016 18.8 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 AAZ37174.1 - 0.0058 17.2 0.1 0.016 15.7 0.1 1.7 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 AAZ37174.1 - 0.18 11.5 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Aldose_epim PF01263.20 AAZ37175.1 - 1.1e-97 327.0 0.5 1.2e-97 326.9 0.5 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase K_oxygenase PF13434.6 AAZ37176.1 - 3.8e-112 374.8 0.0 4.4e-112 374.6 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 AAZ37176.1 - 0.019 14.2 0.0 0.32 10.2 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase RL PF17797.1 AAZ37176.1 - 0.076 13.0 0.9 1.2 9.1 0.6 2.4 2 0 0 2 2 2 0 RL domain NAD_binding_9 PF13454.6 AAZ37176.1 - 0.17 11.9 0.0 1.3 9.0 0.1 2.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding SpoIIE PF07228.12 AAZ37177.1 - 1.1e-32 113.5 0.0 1.9e-32 112.8 0.0 1.4 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Response_reg PF00072.24 AAZ37177.1 - 4e-28 97.8 0.1 6.3e-28 97.2 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain B12-binding PF02310.19 AAZ37177.1 - 0.0023 18.0 0.6 0.0097 15.9 0.1 2.2 2 1 1 3 3 3 1 B12 binding domain ThiG PF05690.14 AAZ37177.1 - 0.086 12.1 0.1 0.15 11.3 0.1 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG DHBP_synthase PF00926.19 AAZ37178.1 - 1.5e-78 262.7 0.4 3.2e-78 261.7 0.4 1.5 2 0 0 2 2 2 1 3,4-dihydroxy-2-butanone 4-phosphate synthase GTP_cyclohydro2 PF00925.20 AAZ37178.1 - 1.5e-27 96.2 0.0 3e-27 95.2 0.0 1.5 1 0 0 1 1 1 1 GTP cyclohydrolase II Lactamase_B_2 PF12706.7 AAZ37179.1 - 7.6e-20 71.3 0.1 1e-19 70.9 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 AAZ37179.1 - 2.2e-08 34.4 0.4 3.3e-08 33.8 0.4 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 AAZ37179.1 - 0.00046 20.1 0.0 0.0015 18.5 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DnaB_C PF03796.15 AAZ37180.1 - 5.8e-112 373.1 0.0 9.3e-112 372.5 0.0 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain DnaB PF00772.21 AAZ37180.1 - 7.4e-37 125.6 0.0 3.6e-36 123.4 0.0 2.0 2 0 0 2 2 2 1 DnaB-like helicase N terminal domain AAA_25 PF13481.6 AAZ37180.1 - 6.6e-12 45.4 0.0 1.2e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 AAZ37180.1 - 5.7e-07 29.1 0.1 7.9e-05 22.1 0.0 2.6 1 1 0 2 2 2 1 KaiC AAA_22 PF13401.6 AAZ37180.1 - 0.00074 19.8 0.0 0.003 17.8 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 AAZ37180.1 - 0.0018 18.4 0.3 0.011 15.9 0.0 2.5 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 AAZ37180.1 - 0.0043 17.1 0.2 1.6 8.9 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase KTI12 PF08433.10 AAZ37180.1 - 0.016 14.6 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ATPase_2 PF01637.18 AAZ37180.1 - 0.079 12.9 0.0 0.21 11.5 0.0 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea FtsK_SpoIIIE PF01580.18 AAZ37180.1 - 0.13 11.6 0.0 0.76 9.1 0.0 2.2 3 0 0 3 3 3 0 FtsK/SpoIIIE family PSY3 PF16836.5 AAZ37180.1 - 0.15 11.6 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Shu complex component Psy3, DNA-binding description AAA_24 PF13479.6 AAZ37180.1 - 0.15 11.7 0.0 1.5 8.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain BPD_transp_1 PF00528.22 AAZ37181.1 - 7.7e-19 68.1 12.8 7.7e-19 68.1 12.8 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component TNFR_16_TM PF18422.1 AAZ37181.1 - 3.5 7.7 5.2 2.9 7.9 0.5 2.7 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain E1-E2_ATPase PF00122.20 AAZ37181.1 - 4.6 6.7 6.2 0.33 10.4 0.6 2.0 3 0 0 3 3 3 0 E1-E2 ATPase UvrB_inter PF17757.1 AAZ37182.1 - 6.1e-32 109.7 0.1 2.1e-31 108.0 0.0 2.0 2 0 0 2 2 2 1 UvrB interaction domain UvrB PF12344.8 AAZ37182.1 - 4.9e-21 74.3 0.0 1.8e-20 72.5 0.0 2.0 1 0 0 1 1 1 1 Ultra-violet resistance protein B Helicase_C PF00271.31 AAZ37182.1 - 6.3e-17 61.9 0.1 1.5e-16 60.7 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 AAZ37182.1 - 3.1e-10 40.3 0.0 1.5e-09 38.0 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UVR PF02151.19 AAZ37182.1 - 6.8e-09 35.2 6.7 2.2e-08 33.6 6.7 2.0 1 0 0 1 1 1 1 UvrB/uvrC motif DEAD PF00270.29 AAZ37182.1 - 5.1e-05 23.1 0.0 0.00035 20.4 0.0 2.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_30 PF13604.6 AAZ37182.1 - 0.0015 18.2 0.0 0.0095 15.7 0.0 2.3 3 0 0 3 3 3 1 AAA domain FlaG PF03646.15 AAZ37182.1 - 0.025 14.7 0.2 0.5 10.6 0.5 2.4 2 0 0 2 2 2 0 FlaG protein AAA_22 PF13401.6 AAZ37182.1 - 0.11 12.8 0.1 0.83 9.9 0.0 2.6 3 0 0 3 3 3 0 AAA domain Cauli_AT PF03233.13 AAZ37182.1 - 0.18 11.7 0.7 0.45 10.4 0.1 2.0 3 0 0 3 3 3 0 Aphid transmission protein DUF2387 PF09526.10 AAZ37183.1 - 3.3e-33 113.7 0.3 3.8e-33 113.4 0.3 1.0 1 0 0 1 1 1 1 Probable metal-binding protein (DUF2387) Hormone_6 PF00236.18 AAZ37183.1 - 0.029 14.4 0.3 0.035 14.1 0.3 1.3 1 1 0 1 1 1 0 Glycoprotein hormone DctQ PF04290.12 AAZ37184.1 - 6.8e-23 81.0 9.6 1.1e-22 80.4 9.6 1.3 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporters, DctQ component UPF0182 PF03699.13 AAZ37184.1 - 0.044 11.9 1.1 0.057 11.6 1.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) DUF5056 PF16479.5 AAZ37184.1 - 0.064 13.5 2.4 0.064 13.5 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5056) TMPIT PF07851.13 AAZ37184.1 - 0.16 11.2 0.7 0.22 10.7 0.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein TrbC PF04956.13 AAZ37184.1 - 0.45 10.8 10.3 2.2 8.5 4.7 2.4 1 1 1 2 2 2 0 TrbC/VIRB2 family DUF4134 PF13572.6 AAZ37184.1 - 3.4 8.0 9.0 0.93 9.8 2.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4134) DUF373 PF04123.13 AAZ37184.1 - 4 6.8 6.9 9.2 5.6 6.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF373) NAD_binding_2 PF03446.15 AAZ37185.1 - 3.5e-40 137.8 0.0 5.1e-40 137.2 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 6PGD PF00393.19 AAZ37185.1 - 3.6e-23 82.4 0.3 1.6e-22 80.3 0.3 2.5 1 1 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain F420_oxidored PF03807.17 AAZ37185.1 - 1.4e-06 28.8 0.0 2.6e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 AAZ37185.1 - 5.7e-05 22.5 0.0 9.1e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 AAZ37185.1 - 0.00017 21.9 0.2 0.00052 20.3 0.1 1.9 1 1 1 2 2 2 1 TrkA-N domain 3HCDH_N PF02737.18 AAZ37185.1 - 0.00035 20.5 0.1 0.00071 19.5 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 AAZ37185.1 - 0.0018 19.1 0.0 0.004 18.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Sacchrp_dh_NADP PF03435.18 AAZ37185.1 - 0.0087 16.3 0.0 0.069 13.4 0.0 2.1 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 AAZ37185.1 - 0.015 14.9 0.2 0.029 14.0 0.2 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 AAZ37185.1 - 0.019 15.1 0.2 0.046 13.8 0.1 1.7 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_11 PF14833.6 AAZ37185.1 - 0.057 13.7 0.3 0.53 10.5 0.1 2.7 2 1 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Gp_dh_N PF00044.24 AAZ37185.1 - 0.17 12.3 0.2 0.34 11.3 0.2 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 AAZ37185.1 - 0.2 11.6 0.0 0.7 9.9 0.0 1.9 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DapB_N PF01113.20 AAZ37185.1 - 0.21 11.7 1.3 0.89 9.7 1.3 2.0 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GST_N_3 PF13417.6 AAZ37186.1 - 5.5e-17 62.0 0.0 8.7e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AAZ37186.1 - 1.5e-16 60.4 0.0 3e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 AAZ37186.1 - 5.6e-14 52.2 0.0 1e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 AAZ37186.1 - 3.4e-05 23.8 0.4 7e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 AAZ37186.1 - 0.0012 19.0 0.0 0.0022 18.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 AAZ37186.1 - 0.002 18.4 0.0 0.0042 17.4 0.0 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein MAAL_N PF05034.13 AAZ37186.1 - 0.041 13.5 0.0 0.099 12.3 0.0 1.5 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase N-terminus GST_C_3 PF14497.6 AAZ37186.1 - 0.091 13.0 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 AAZ37186.1 - 0.12 13.1 0.0 0.32 11.8 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase N-terminal domain CxxCxxCC PF03692.15 AAZ37187.1 - 1.6e-05 25.5 2.2 4e-05 24.2 2.2 1.6 1 1 0 1 1 1 1 Putative zinc- or iron-chelating domain Resolvase PF00239.21 AAZ37188.1 - 3e-37 127.9 0.0 5.2e-37 127.2 0.0 1.3 1 0 0 1 1 1 1 Resolvase, N terminal domain Trp_repressor PF01371.19 AAZ37188.1 - 0.12 12.6 0.1 0.25 11.5 0.1 1.5 1 0 0 1 1 1 0 Trp repressor protein HTH_3 PF01381.22 AAZ37188.1 - 0.19 11.8 1.1 0.46 10.6 0.2 2.2 3 0 0 3 3 3 0 Helix-turn-helix DUF3309 PF11752.8 AAZ37190.1 - 1.2e-21 76.5 19.4 1.3e-21 76.4 19.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3309) PDGLE PF13190.6 AAZ37190.1 - 0.21 11.5 0.2 0.21 11.5 0.2 1.9 2 0 0 2 2 2 0 PDGLE domain DUF444 PF04285.12 AAZ37191.1 - 2.2e-179 597.0 0.3 2.5e-179 596.8 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF444) VWA_2 PF13519.6 AAZ37191.1 - 0.13 12.9 0.1 0.98 10.1 0.1 2.5 2 1 0 2 2 2 0 von Willebrand factor type A domain Malic_M PF03949.15 AAZ37192.1 - 3e-102 341.3 0.9 4e-102 340.9 0.9 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 AAZ37192.1 - 8.2e-75 250.6 0.0 1.3e-74 249.9 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain ADH_zinc_N PF00107.26 AAZ37192.1 - 0.037 14.0 0.1 0.074 13.0 0.1 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Shikimate_DH PF01488.20 AAZ37192.1 - 0.18 11.9 0.2 0.6 10.2 0.2 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NMT1 PF09084.11 AAZ37193.1 - 4.7e-28 98.6 0.0 6.9e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.7 AAZ37193.1 - 1.1e-11 44.8 0.1 1.7e-11 44.2 0.1 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1_2 PF13379.6 AAZ37193.1 - 4.2e-09 36.5 0.0 9e-09 35.4 0.0 1.6 1 1 0 1 1 1 1 NMT1-like family SBP_bac_3 PF00497.20 AAZ37193.1 - 1.1e-06 28.2 0.0 2e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1_3 PF16868.5 AAZ37193.1 - 2.4e-06 27.2 0.0 4.9e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 NMT1-like family PBP_like_2 PF12849.7 AAZ37193.1 - 0.04 13.6 0.1 0.16 11.6 0.0 1.8 2 0 0 2 2 2 0 PBP superfamily domain Meth_synt_1 PF08267.12 AAZ37194.1 - 2e-40 139.2 0.0 2.3e-37 129.2 0.0 2.0 1 1 1 2 2 2 2 Cobalamin-independent synthase, N-terminal domain Meth_synt_2 PF01717.18 AAZ37194.1 - 0.0032 16.8 0.0 0.0041 16.4 0.0 1.1 1 0 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Ribonuc_red_sm PF00268.21 AAZ37196.1 - 9.4e-87 291.0 0.5 1.2e-86 290.7 0.5 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain PPP5 PF08321.12 AAZ37196.1 - 0.062 13.6 0.0 0.17 12.2 0.0 1.8 1 0 0 1 1 1 0 PPP5 TPR repeat region MFS_1 PF07690.16 AAZ37197.1 - 4.5e-50 170.6 32.5 1.7e-48 165.3 27.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 AAZ37197.1 - 0.00049 19.2 11.1 0.003 16.6 1.3 3.3 3 1 0 3 3 3 3 Nucleoside H+ symporter DUF1146 PF06612.11 AAZ37197.1 - 0.018 15.1 1.0 15 5.8 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1146) DUF373 PF04123.13 AAZ37197.1 - 0.097 12.1 4.5 0.58 9.5 1.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF373) DcrB PF08786.11 AAZ37198.1 - 8.1e-33 113.2 0.0 9.2e-33 113.1 0.0 1.0 1 0 0 1 1 1 1 DcrB SecD-TM1 PF13721.6 AAZ37199.1 - 3.6e-37 126.9 1.3 3.2e-33 114.3 0.0 3.3 3 0 0 3 3 3 2 SecD export protein N-terminal TM region SecD_SecF PF02355.16 AAZ37199.1 - 4e-17 62.2 12.9 5.6e-17 61.8 12.1 1.6 2 0 0 2 2 2 1 Protein export membrane protein MMPL PF03176.15 AAZ37199.1 - 3.2e-07 29.6 18.7 6.2e-07 28.7 18.7 1.4 1 0 0 1 1 1 1 MMPL family Sec_GG PF07549.14 AAZ37199.1 - 2.1e-06 27.0 0.0 7.1e-06 25.3 0.0 2.0 2 0 0 2 2 2 1 SecD/SecF GG Motif ACR_tran PF00873.19 AAZ37199.1 - 0.0043 14.8 14.2 0.0072 14.0 14.2 1.2 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family Patched PF02460.18 AAZ37199.1 - 9.4 4.2 13.9 13 3.7 13.9 1.1 1 0 0 1 1 1 0 Patched family ComP_DUS PF16732.5 AAZ37200.1 - 5e-17 62.6 0.5 7.1e-17 62.1 0.5 1.2 1 0 0 1 1 1 1 Type IV minor pilin ComP, DNA uptake sequence receptor N_methyl PF07963.12 AAZ37200.1 - 2.4e-10 39.5 2.5 5.4e-10 38.4 2.5 1.7 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif Phospholip_B PF04916.13 AAZ37200.1 - 0.035 12.7 0.1 0.04 12.5 0.1 1.1 1 0 0 1 1 1 0 Phospholipase B AAA_21 PF13304.6 AAZ37201.1 - 6.3e-27 95.2 0.1 9.1e-27 94.6 0.1 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AAZ37201.1 - 1.3e-17 64.6 0.0 1.3e-09 38.3 0.0 2.3 1 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 AAZ37201.1 - 9.7e-14 52.3 0.0 1.7e-13 51.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 AAZ37201.1 - 1.1e-09 38.0 0.0 3.7e-09 36.4 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_tran PF00005.27 AAZ37201.1 - 1.7e-07 31.8 0.1 8.1e-05 23.2 0.0 2.6 2 0 0 2 2 2 1 ABC transporter AAA PF00004.29 AAZ37201.1 - 1.4e-05 25.5 0.0 0.0045 17.4 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_27 PF13514.6 AAZ37201.1 - 2.1e-05 24.2 0.0 8.7e-05 22.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 AAZ37201.1 - 0.0002 21.0 0.0 0.00045 19.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AAZ37201.1 - 0.00034 20.9 0.6 0.044 14.1 0.1 2.8 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 AAZ37201.1 - 0.00037 20.4 0.1 0.001 19.0 0.1 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 AAZ37201.1 - 0.00042 20.7 0.4 0.0021 18.5 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 AAZ37201.1 - 0.0013 18.7 2.1 0.037 14.0 0.3 2.8 3 0 0 3 3 3 1 NACHT domain AAA_33 PF13671.6 AAZ37201.1 - 0.0047 17.1 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 AAZ37201.1 - 0.0073 16.3 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 AAZ37201.1 - 0.0081 16.2 0.0 1.8 8.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 AAZ37201.1 - 0.024 14.4 0.2 0.054 13.2 0.2 1.5 1 0 0 1 1 1 0 AAA domain MetRS-N PF09635.10 AAZ37201.1 - 0.029 14.9 0.1 0.2 12.2 0.1 2.1 1 1 0 1 1 1 0 MetRS-N binding domain cobW PF02492.19 AAZ37201.1 - 0.03 13.9 0.2 0.061 12.9 0.2 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AF0941-like PF14591.6 AAZ37201.1 - 0.032 14.8 0.1 0.35 11.4 0.1 2.2 2 0 0 2 2 2 0 AF0941-like NTPase_1 PF03266.15 AAZ37201.1 - 0.037 13.9 0.2 1.4 8.8 0.1 2.5 2 0 0 2 2 2 0 NTPase SRP54 PF00448.22 AAZ37201.1 - 0.068 12.8 0.2 0.14 11.8 0.2 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_19 PF13245.6 AAZ37201.1 - 0.07 13.5 0.2 0.82 10.0 0.1 2.2 2 1 0 2 2 2 0 AAA domain MukB PF04310.12 AAZ37201.1 - 0.078 12.8 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 MukB N-terminal AAA_25 PF13481.6 AAZ37201.1 - 0.079 12.5 0.2 0.25 10.9 0.2 1.8 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 AAZ37201.1 - 0.079 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.22 AAZ37201.1 - 0.095 11.9 0.0 0.72 9.0 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain MobB PF03205.14 AAZ37201.1 - 0.12 12.3 0.1 0.29 11.0 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_13 PF13166.6 AAZ37201.1 - 0.16 10.6 0.0 4.9 5.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain eIF-1a PF01176.19 AAZ37202.1 - 1.5e-27 95.2 0.1 1.6e-27 95.1 0.1 1.0 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 RsgA_N PF16745.5 AAZ37202.1 - 2e-05 24.2 0.0 2.4e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 RsgA N-terminal domain S1 PF00575.23 AAZ37202.1 - 0.011 16.1 0.0 0.015 15.7 0.0 1.2 1 0 0 1 1 1 0 S1 RNA binding domain RNase_II_C_S1 PF18614.1 AAZ37202.1 - 0.033 14.1 0.1 0.19 11.7 0.1 2.1 1 1 0 1 1 1 0 RNase II-type exonuclease C-terminal S1 domain OB_aCoA_assoc PF01796.17 AAZ37202.1 - 0.13 12.3 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 DUF35 OB-fold domain, acyl-CoA-associated CSD2 PF17876.1 AAZ37202.1 - 0.13 12.5 0.0 4.4 7.5 0.0 2.5 1 1 2 3 3 3 0 Cold shock domain DUF4398 PF14346.6 AAZ37203.1 - 5.7e-14 52.5 19.5 8.3e-14 52.0 18.9 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4398) PBP_sp32 PF07222.12 AAZ37203.1 - 0.14 11.5 1.6 0.18 11.2 1.6 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Exonuc_X-T_C PF08411.10 AAZ37204.1 - 3.3e-99 331.4 0.2 4.1e-99 331.1 0.2 1.1 1 0 0 1 1 1 1 Exonuclease C-terminal RNase_T PF00929.24 AAZ37204.1 - 2.5e-23 83.4 0.0 4.5e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 Exonuclease CheD PF03975.13 AAZ37205.1 - 8.4e-26 90.2 0.0 1.1e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 CheD chemotactic sensory transduction GerE PF00196.19 AAZ37206.1 - 9.8e-07 28.2 0.1 1e-06 28.1 0.1 1.0 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family PsiF_repeat PF07769.14 AAZ37206.1 - 0.12 12.3 0.1 0.12 12.3 0.1 1.6 2 0 0 2 2 2 0 psiF repeat MFS_1 PF07690.16 AAZ37207.1 - 1.1e-29 103.5 30.7 1.4e-29 103.2 30.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 AAZ37207.1 - 5.4e-06 25.5 12.6 5.4e-06 25.5 12.6 2.1 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.7 AAZ37207.1 - 0.69 8.7 12.6 0.3 9.9 7.9 2.0 1 1 1 2 2 2 0 MFS_1 like family IPTL-CTERM PF18203.1 AAZ37207.1 - 1.9 8.5 13.7 0.16 11.9 6.6 3.0 2 0 0 2 2 2 0 IPTL-CTERM motif Secretin PF00263.21 AAZ37208.1 - 9.1e-34 116.5 0.3 1.4e-33 115.9 0.3 1.3 1 0 0 1 1 1 1 Bacterial type II and III secretion system protein Secretin_N PF03958.17 AAZ37208.1 - 6.5e-29 100.2 0.6 1.2e-21 76.9 0.3 2.9 2 0 0 2 2 2 2 Bacterial type II/III secretion system short domain TraK PF06586.11 AAZ37208.1 - 0.0045 16.7 0.0 0.008 15.9 0.0 1.4 1 0 0 1 1 1 1 TraK protein Bac_DNA_binding PF00216.21 AAZ37210.1 - 5.7e-32 109.8 0.3 6.3e-32 109.6 0.3 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 AAZ37210.1 - 0.00024 21.2 0.0 0.00025 21.1 0.0 1.0 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_bac_2 PF18175.1 AAZ37210.1 - 0.0014 18.5 0.0 0.0025 17.7 0.0 1.4 2 0 0 2 2 2 1 CCDC81-like prokaryotic HU domain 2 HU-CCDC81_bac_1 PF18174.1 AAZ37210.1 - 0.005 16.7 0.0 0.0063 16.4 0.0 1.3 1 0 0 1 1 1 1 CCDC81-like prokaryotic HU domain 1 HU-CCDC81_euk_1 PF14908.6 AAZ37210.1 - 0.0079 16.3 0.0 0.0083 16.3 0.0 1.1 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 1 HU-CCDC81_euk_2 PF18289.1 AAZ37210.1 - 0.1 12.8 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 2 Bac_globin PF01152.21 AAZ37211.1 - 8.2e-11 42.1 0.0 1e-10 41.8 0.0 1.0 1 0 0 1 1 1 1 Bacterial-like globin Ribosomal_S17 PF00366.20 AAZ37212.1 - 8.1e-33 112.3 3.1 1e-32 112.0 3.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S17 PepSY_2 PF13670.6 AAZ37213.1 - 0.0018 18.3 2.6 0.0031 17.5 1.2 2.0 2 0 0 2 2 2 1 Peptidase propeptide and YPEB domain STN PF07660.14 AAZ37213.1 - 0.034 14.0 0.0 0.3 10.9 0.0 2.1 2 0 0 2 2 2 0 Secretin and TonB N terminus short domain EarP PF10093.9 AAZ37214.1 - 1.8e-153 511.1 0.2 2e-153 510.9 0.2 1.0 1 0 0 1 1 1 1 Elongation-Factor P (EF-P) rhamnosyltransferase EarP Glyco_trans_4_4 PF13579.6 AAZ37214.1 - 3.9 7.9 10.2 0.19 12.2 0.4 2.4 2 1 0 2 2 2 0 Glycosyl transferase 4-like domain Haem_oxygenas_2 PF14518.6 AAZ37215.1 - 4.2e-22 78.8 0.0 6e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 Iron-containing redox enzyme RmlD_sub_bind PF04321.17 AAZ37216.1 - 1.1e-73 247.8 0.0 1.3e-73 247.6 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 AAZ37216.1 - 0.0013 18.2 0.0 0.0023 17.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Bac_export_3 PF01313.19 AAZ37217.1 - 8.5e-22 76.9 10.6 9.4e-22 76.7 10.6 1.0 1 0 0 1 1 1 1 Bacterial export proteins, family 3 Bac_export_1 PF01311.20 AAZ37217.1 - 0.00067 19.3 7.8 0.00076 19.1 7.8 1.0 1 0 0 1 1 1 1 Bacterial export proteins, family 1 Bac_export_2 PF01312.19 AAZ37217.1 - 0.3 10.3 5.4 4.3 6.4 2.1 2.0 1 1 1 2 2 2 0 FlhB HrpN YscU SpaS Family Rick_17kDa_Anti PF05433.15 AAZ37218.1 - 5.4e-07 29.4 30.0 9.7e-07 28.6 30.0 1.4 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.6 AAZ37218.1 - 2.1e-05 24.1 23.8 4.1e-05 23.2 23.8 1.4 1 0 0 1 1 1 1 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 AAZ37218.1 - 0.00025 21.0 29.1 0.00043 20.2 29.1 1.4 1 0 0 1 1 1 1 Glycine zipper TraT PF05818.12 AAZ37218.1 - 0.018 14.7 3.1 0.021 14.5 3.1 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein DUF3482 PF11981.8 AAZ37218.1 - 0.38 10.1 6.1 0.58 9.5 6.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) ShlB PF03865.13 AAZ37219.1 - 1.5e-32 113.3 0.6 2e-32 112.9 0.6 1.2 1 0 0 1 1 1 1 Haemolysin secretion/activation protein ShlB/FhaC/HecB POTRA_2 PF08479.11 AAZ37219.1 - 3.6e-14 52.3 0.1 6.7e-14 51.5 0.1 1.5 1 0 0 1 1 1 1 POTRA domain, ShlB-type POTRA PF07244.15 AAZ37219.1 - 3.3e-06 27.6 0.0 5.8e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Surface antigen variable number repeat Smr PF01713.21 AAZ37220.1 - 2.6e-21 75.8 0.2 3.9e-21 75.2 0.2 1.3 1 0 0 1 1 1 1 Smr domain EamA PF00892.20 AAZ37221.1 - 3.9e-16 59.5 23.5 2.9e-08 34.0 4.0 2.1 2 0 0 2 2 2 2 EamA-like transporter family HHV-1_VABD PF16852.5 AAZ37221.1 - 0.038 14.0 0.5 0.071 13.1 0.5 1.3 1 0 0 1 1 1 0 Herpes viral adaptor-to-host cellular mRNA binding domain Ycf4 PF02392.16 AAZ37221.1 - 0.11 12.1 2.5 2.1 7.9 0.4 2.3 2 0 0 2 2 2 0 Ycf4 TetR_N PF00440.23 AAZ37223.1 - 3.8e-11 42.6 0.5 7.1e-11 41.7 0.1 1.7 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_22 PF17928.1 AAZ37223.1 - 5.7e-07 29.8 1.7 1.2e-06 28.8 1.7 1.5 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain DUF1353 PF07087.11 AAZ37223.1 - 0.086 12.6 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1353) TetR_C_15 PF17918.1 AAZ37223.1 - 5.8 7.7 11.8 0.29 11.9 4.4 2.3 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Transthyretin PF00576.21 AAZ37224.1 - 3.4e-34 117.8 0.0 3.8e-34 117.7 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family CarboxypepD_reg PF13620.6 AAZ37224.1 - 0.008 16.4 0.0 0.012 15.8 0.0 1.3 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain Phage_integrase PF00589.22 AAZ37225.1 - 4.6e-14 52.6 0.0 1.2e-13 51.2 0.0 1.7 1 1 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 AAZ37225.1 - 0.011 16.0 2.3 0.025 14.9 0.6 2.4 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 AAZ37225.1 - 0.1 13.1 0.0 0.27 11.8 0.0 1.7 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain VWA PF00092.28 AAZ37226.1 - 7.4e-28 98.0 0.0 1.1e-27 97.4 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 AAZ37226.1 - 1.1e-14 55.0 0.0 2e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF1194 PF06707.11 AAZ37226.1 - 1.6e-06 27.5 0.3 0.00068 18.9 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1194) VWA_3 PF13768.6 AAZ37226.1 - 0.03 14.3 0.0 1.1 9.2 0.0 2.6 1 1 0 1 1 1 0 von Willebrand factor type A domain AvrPphF-ORF-2 PF09143.10 AAZ37227.1 - 1.1e-40 139.4 0.0 1.6e-40 138.9 0.0 1.1 1 0 0 1 1 1 1 AvrPphF-ORF-2 Glyco_hydro_19 PF00182.19 AAZ37228.1 - 3.3e-10 40.3 0.0 6.2e-10 39.4 0.0 1.4 1 1 0 1 1 1 1 Chitinase class I BPD_transp_1 PF00528.22 AAZ37229.1 - 2.5e-17 63.2 9.0 2.5e-17 63.2 9.0 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF2273 PF10031.9 AAZ37229.1 - 0.095 12.7 0.1 0.095 12.7 0.1 3.6 3 0 0 3 3 3 0 Small integral membrane protein (DUF2273) COX7C PF02935.16 AAZ37229.1 - 1.5 9.2 9.4 3.9 7.8 0.5 3.8 4 0 0 4 4 4 0 Cytochrome c oxidase subunit VIIc DUF3077 PF11275.8 AAZ37230.1 - 0.0097 16.1 0.3 0.013 15.7 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3077) GMP_synt_C PF00958.22 AAZ37232.1 - 1.5e-41 140.4 0.1 2.9e-41 139.4 0.1 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 AAZ37232.1 - 4.3e-36 124.5 0.0 7.2e-36 123.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 AAZ37232.1 - 1.9e-10 40.3 0.2 3.9e-08 32.7 0.1 2.1 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 AAZ37232.1 - 5.7e-08 32.8 0.0 3.9e-07 30.1 0.0 2.4 1 1 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 AAZ37232.1 - 4.5e-05 22.4 0.0 0.00014 20.8 0.0 1.7 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.13 AAZ37232.1 - 0.00043 19.8 0.0 0.21 11.1 0.0 2.2 2 0 0 2 2 2 2 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.20 AAZ37232.1 - 0.0022 17.8 0.0 0.0036 17.1 0.0 1.3 1 0 0 1 1 1 1 PP-loop family Asn_synthase PF00733.21 AAZ37232.1 - 0.0025 17.5 0.1 0.0039 16.9 0.1 1.2 1 0 0 1 1 1 1 Asparagine synthase PAPS_reduct PF01507.19 AAZ37232.1 - 0.012 15.7 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family ThiI PF02568.14 AAZ37232.1 - 0.18 11.4 0.1 0.33 10.5 0.1 1.4 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) MotA_ExbB PF01618.16 AAZ37233.1 - 3e-35 120.7 0.4 4.8e-35 120.1 0.4 1.3 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family DUF3397 PF11877.8 AAZ37233.1 - 0.04 14.1 0.2 0.1 12.8 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3397) MotB_plug PF13677.6 AAZ37234.1 - 9.5e-18 63.6 0.1 2.1e-17 62.5 0.1 1.6 1 0 0 1 1 1 1 Membrane MotB of proton-channel complex MotA/MotB OmpA PF00691.20 AAZ37234.1 - 7.2e-13 48.7 0.0 1.6e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 OmpA family RBD-FIP PF09457.10 AAZ37234.1 - 0.024 14.5 1.3 2.3 8.2 1.8 2.4 2 0 0 2 2 2 0 FIP domain Biotin_lipoyl PF00364.22 AAZ37235.1 - 1.7e-26 91.8 0.3 3e-26 91.0 0.3 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 AAZ37235.1 - 1e-08 34.9 1.6 0.00031 20.5 0.0 2.7 2 1 1 3 3 3 2 Biotin-lipoyl like HlyD_D23 PF16576.5 AAZ37235.1 - 0.0013 17.9 0.1 0.02 14.1 0.0 2.3 2 1 1 3 3 3 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion YqfD PF06898.11 AAZ37235.1 - 0.0016 17.4 1.7 0.031 13.1 0.1 2.2 1 1 1 2 2 2 1 Putative stage IV sporulation protein YqfD GCV_H PF01597.19 AAZ37235.1 - 0.0036 17.2 0.1 0.0059 16.5 0.1 1.3 1 0 0 1 1 1 1 Glycine cleavage H-protein HlyD_3 PF13437.6 AAZ37235.1 - 0.0051 17.5 0.1 0.033 14.9 0.1 2.2 2 0 0 2 2 2 1 HlyD family secretion protein RnfC_N PF13375.6 AAZ37235.1 - 0.0084 16.0 0.0 0.02 14.9 0.0 1.6 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Ribosomal_60s PF00428.19 AAZ37235.1 - 0.013 16.1 2.8 0.028 15.0 2.8 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Peptidase_M23 PF01551.22 AAZ37235.1 - 0.042 14.1 0.0 0.13 12.5 0.0 1.8 1 1 0 1 1 1 0 Peptidase family M23 IclR PF01614.18 AAZ37236.1 - 5.1e-42 142.7 0.1 3.2e-41 140.2 0.0 2.0 2 0 0 2 2 2 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 AAZ37236.1 - 2e-14 53.1 0.5 5.1e-14 51.8 0.5 1.7 1 0 0 1 1 1 1 IclR helix-turn-helix domain Rrf2 PF02082.20 AAZ37236.1 - 0.0015 18.9 0.0 0.0039 17.5 0.0 1.7 1 0 0 1 1 1 1 Transcriptional regulator HTH_9 PF08221.11 AAZ37236.1 - 0.003 17.6 0.0 0.0059 16.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 helix-turn-helix domain HTH_24 PF13412.6 AAZ37236.1 - 0.0057 16.2 0.0 0.015 14.8 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding DUF4423 PF14394.6 AAZ37236.1 - 0.0081 15.9 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) MarR_2 PF12802.7 AAZ37236.1 - 0.011 15.7 0.2 0.011 15.7 0.2 2.3 3 0 0 3 3 3 0 MarR family TrmB PF01978.19 AAZ37236.1 - 0.013 15.4 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Cullin PF00888.22 AAZ37236.1 - 0.025 13.2 0.0 0.037 12.7 0.0 1.1 1 0 0 1 1 1 0 Cullin family HTH_11 PF08279.12 AAZ37236.1 - 0.027 14.4 0.3 0.083 12.8 0.0 1.9 2 0 0 2 2 2 0 HTH domain HTH_5 PF01022.20 AAZ37236.1 - 0.046 13.6 0.0 0.098 12.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family LytB_WW PF18342.1 AAZ37236.1 - 0.05 13.7 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Endo-beta-N-acetylglucosaminidase LytB WW domain PsiE PF06146.12 AAZ37237.1 - 6.3e-17 61.7 2.7 1.1e-16 60.9 2.7 1.4 1 0 0 1 1 1 1 Phosphate-starvation-inducible E Ribosomal_L16 PF00252.18 AAZ37238.1 - 2.7e-47 160.1 0.5 3e-47 159.9 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e CT_C_D PF02682.16 AAZ37239.1 - 3.4e-55 186.9 0.0 3.8e-55 186.8 0.0 1.0 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D DUF58 PF01882.18 AAZ37240.1 - 1.4e-20 73.3 0.1 5.4e-20 71.5 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function DUF58 VWA_2 PF13519.6 AAZ37240.1 - 0.00033 21.3 0.0 0.00081 20.0 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain DAHP_synth_1 PF00793.20 AAZ37241.1 - 1.2e-94 316.2 0.0 1.5e-94 315.9 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Peripla_BP_2 PF01497.18 AAZ37242.1 - 5.6e-20 71.9 0.0 7.2e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein Transposase_mut PF00872.18 AAZ37243.1 - 1.5e-117 392.7 0.0 1.9e-117 392.3 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ37243.1 - 7.7e-05 23.0 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain DUF4844 PF16133.5 AAZ37243.1 - 0.23 12.0 0.0 0.55 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) T6SS_HCP PF05638.12 AAZ37244.1 - 1.8e-40 138.3 0.0 2.2e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 Type VI secretion system effector, Hcp ALGX PF16822.5 AAZ37245.1 - 0.00016 21.4 0.0 0.00042 20.1 0.0 1.9 1 1 0 1 1 1 1 SGNH hydrolase-like domain, acetyltransferase AlgX DHHW PF14286.6 AAZ37245.1 - 0.0072 15.7 0.1 0.01 15.2 0.1 1.3 1 0 0 1 1 1 1 DHHW protein ZnuA PF01297.17 AAZ37246.1 - 1.6e-14 54.0 0.0 1.7e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Zinc-uptake complex component A periplasmic UPF0176_N PF17773.1 AAZ37247.1 - 2.6e-25 88.6 0.0 4.1e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese PF00581.20 AAZ37247.1 - 2.1e-06 28.2 0.0 5.6e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain Rhodanese_C PF12368.8 AAZ37247.1 - 1.6e-05 25.1 1.0 3.2e-05 24.2 1.0 1.5 1 0 0 1 1 1 1 Rhodanase C-terminal DZR PF12773.7 AAZ37247.1 - 0.03 14.4 0.6 0.077 13.0 0.6 1.7 1 0 0 1 1 1 0 Double zinc ribbon Acylphosphatase PF00708.18 AAZ37247.1 - 0.058 13.8 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Acylphosphatase zinc_ribbon_9 PF14369.6 AAZ37247.1 - 0.12 12.6 5.2 0.33 11.2 5.2 1.7 1 0 0 1 1 1 0 zinc-ribbon S1 PF00575.23 AAZ37248.1 - 7.6e-97 317.8 31.2 2.4e-21 75.8 0.3 6.1 6 0 0 6 6 6 6 S1 RNA binding domain PCB_OB PF17092.5 AAZ37248.1 - 2.4e-10 41.2 6.3 0.097 13.4 0.1 5.5 2 1 2 5 5 5 3 Penicillin-binding protein OB-like domain S1_2 PF13509.6 AAZ37248.1 - 1.1e-05 25.3 9.0 2.2 8.4 0.2 6.7 6 2 0 6 6 6 2 S1 domain CsrA PF02599.16 AAZ37248.1 - 0.0095 15.9 6.1 3.1 7.8 0.1 4.2 4 0 0 4 4 4 2 Global regulator protein family RsgI_N PF12791.7 AAZ37248.1 - 0.063 13.2 4.8 1.1 9.3 0.0 3.6 4 0 0 4 4 4 0 Anti-sigma factor N-terminus SH3_1 PF00018.28 AAZ37248.1 - 0.1 12.2 1.4 17 5.1 0.0 3.5 4 0 0 4 4 4 0 SH3 domain BPL_C PF02237.17 AAZ37248.1 - 0.15 12.0 17.6 8.8 6.3 0.2 6.1 8 0 0 8 8 8 0 Biotin protein ligase C terminal domain TOBE_2 PF08402.10 AAZ37248.1 - 0.2 11.8 4.6 0.66 10.2 0.0 4.0 5 2 1 6 6 6 0 TOBE domain DUF1344 PF07076.11 AAZ37248.1 - 9.1 6.3 11.1 19 5.2 0.2 4.9 6 0 0 6 6 6 0 Protein of unknown function (DUF1344) Peripla_BP_4 PF13407.6 AAZ37251.1 - 5.8e-46 157.2 8.7 6.6e-46 157.0 8.7 1.0 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 AAZ37251.1 - 6.8e-13 48.7 0.1 8.7e-13 48.3 0.1 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_6 PF13458.6 AAZ37251.1 - 5.3e-07 29.6 1.3 7.7e-07 29.1 1.3 1.2 1 0 0 1 1 1 1 Periplasmic binding protein Peripla_BP_3 PF13377.6 AAZ37251.1 - 0.0013 19.1 0.0 0.013 15.9 0.0 2.0 2 0 0 2 2 2 1 Periplasmic binding protein-like domain AAA_30 PF13604.6 AAZ37251.1 - 0.0023 17.7 0.1 0.0069 16.1 0.1 1.8 1 1 0 1 1 1 1 AAA domain ANF_receptor PF01094.28 AAZ37251.1 - 0.0046 16.1 0.0 0.0073 15.5 0.0 1.4 1 1 0 1 1 1 1 Receptor family ligand binding region DUF5421 PF17458.2 AAZ37251.1 - 0.0048 16.3 0.1 0.0077 15.7 0.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5421) PucR PF07905.11 AAZ37251.1 - 0.0078 16.5 0.0 0.016 15.5 0.0 1.6 1 0 0 1 1 1 1 Purine catabolism regulatory protein-like family PK_C PF02887.16 AAZ37251.1 - 0.057 13.6 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Pyruvate kinase, alpha/beta domain Hpr_kinase_N PF02603.16 AAZ37251.1 - 0.17 11.9 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 HPr Serine kinase N terminus Cutinase PF01083.22 AAZ37251.1 - 0.2 11.6 0.8 1 9.3 0.1 2.4 2 1 1 3 3 3 0 Cutinase Dioxygenase_C PF00775.21 AAZ37252.1 - 5.2e-57 192.2 0.0 6.4e-57 191.9 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase PCDO_beta_N PF12391.8 AAZ37252.1 - 2e-16 59.3 1.1 4.6e-16 58.1 1.1 1.6 1 0 0 1 1 1 1 Protocatechuate 3,4-dioxygenase beta subunit N terminal CarboxypepD_reg PF13620.6 AAZ37252.1 - 1e-05 25.7 0.0 2.5e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4198 PF10670.9 AAZ37252.1 - 0.15 12.4 0.0 0.24 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) SdrD_B PF17210.3 AAZ37252.1 - 0.17 12.1 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 SdrD B-like domain CarbopepD_reg_2 PF13715.6 AAZ37252.1 - 0.18 11.9 0.0 1.4 8.9 0.0 2.0 2 0 0 2 2 2 0 CarboxypepD_reg-like domain UPF0060 PF02694.15 AAZ37254.1 - 8.8e-29 99.9 11.9 9.8e-29 99.7 11.9 1.0 1 0 0 1 1 1 1 Uncharacterised BCR, YnfA/UPF0060 family Multi_Drug_Res PF00893.19 AAZ37254.1 - 0.037 14.7 8.0 0.031 14.9 7.3 1.3 1 1 0 1 1 1 0 Small Multidrug Resistance protein MerR_1 PF13411.6 AAZ37255.1 - 3.6e-16 59.0 0.3 6.5e-16 58.2 0.3 1.4 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR-DNA-bind PF09278.11 AAZ37255.1 - 1.5e-13 51.0 3.4 1.5e-13 51.0 3.4 1.6 2 0 0 2 2 2 1 MerR, DNA binding MerR PF00376.23 AAZ37255.1 - 1.3e-09 37.7 0.2 2.1e-09 37.0 0.2 1.4 1 0 0 1 1 1 1 MerR family regulatory protein HTH_11 PF08279.12 AAZ37255.1 - 0.02 14.8 0.2 0.067 13.1 0.1 2.0 2 0 0 2 2 2 0 HTH domain Lge1 PF11488.8 AAZ37255.1 - 0.032 14.4 1.6 0.051 13.8 0.9 1.8 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 HTH_3 PF01381.22 AAZ37255.1 - 0.14 12.3 4.8 0.19 11.8 0.1 3.1 2 1 2 4 4 4 0 Helix-turn-helix ParE_toxin PF05016.15 AAZ37256.1 - 2e-18 66.8 0.0 2.2e-18 66.6 0.0 1.0 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE DUF4065 PF13274.6 AAZ37257.1 - 1.6e-17 64.4 0.0 2.4e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4065) ABC_tran PF00005.27 AAZ37258.1 - 1.1e-36 126.4 0.0 1.8e-36 125.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter NIL PF09383.10 AAZ37258.1 - 2.5e-18 65.7 0.0 5.6e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 NIL domain AAA_21 PF13304.6 AAZ37258.1 - 3e-06 27.3 0.1 0.076 12.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAZ37258.1 - 7.3e-06 25.6 1.2 9.7e-05 21.9 1.2 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AAZ37258.1 - 2.1e-05 24.8 0.6 0.00024 21.4 0.4 2.4 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 AAZ37258.1 - 4.6e-05 23.2 0.3 0.00095 18.9 0.3 2.5 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AAZ37258.1 - 0.00068 20.1 0.6 0.002 18.5 0.6 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AAZ37258.1 - 0.0024 17.6 0.1 0.005 16.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AAZ37258.1 - 0.0089 15.9 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 AAZ37258.1 - 0.01 16.4 0.0 0.025 15.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 AAZ37258.1 - 0.011 16.2 0.2 0.15 12.5 0.2 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 AAZ37258.1 - 0.012 15.1 0.1 0.25 10.7 0.1 2.3 2 0 0 2 2 2 0 Bacterial TniB protein SbcCD_C PF13558.6 AAZ37258.1 - 0.016 15.4 0.2 0.17 12.1 0.2 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 AAZ37258.1 - 0.022 14.9 0.6 0.12 12.4 0.3 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase KAP_NTPase PF07693.14 AAZ37258.1 - 0.039 13.2 0.0 0.23 10.6 0.0 2.1 1 1 0 1 1 1 0 KAP family P-loop domain AAA_33 PF13671.6 AAZ37258.1 - 0.075 13.2 0.1 0.17 12.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.17 AAZ37258.1 - 0.093 12.8 0.5 0.17 11.9 0.5 1.6 1 1 0 1 1 1 0 Helicase HerA, central domain AAA_5 PF07728.14 AAZ37258.1 - 0.13 12.3 0.1 17 5.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 AAZ37258.1 - 0.23 10.6 0.9 1 8.5 0.9 1.9 1 1 0 1 1 1 0 NB-ARC domain EI24 PF07264.11 AAZ37259.1 - 1.6e-34 119.7 22.9 1.8e-34 119.5 22.9 1.0 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) SdpI PF13630.6 AAZ37259.1 - 2.3 8.4 9.6 0.94 9.7 0.5 3.0 2 2 0 2 2 2 0 SdpI/YhfL protein family DUF1980 PF09323.10 AAZ37259.1 - 3.2 7.6 4.8 0.95 9.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DUF997 PF06196.12 AAZ37259.1 - 9.7 6.3 17.8 11 6.1 12.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF997) Ribosomal_L9_C PF03948.14 AAZ37261.1 - 6.6e-28 97.0 0.5 1.2e-27 96.2 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L9, C-terminal domain Ribosomal_L9_N PF01281.19 AAZ37261.1 - 2e-19 68.9 1.0 4.2e-19 67.8 1.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain NatB_MDM20 PF09797.9 AAZ37261.1 - 0.12 11.3 0.1 0.14 11.0 0.1 1.1 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit PRA1 PF03208.19 AAZ37262.1 - 0.0019 17.8 1.9 0.0028 17.3 1.9 1.2 1 0 0 1 1 1 1 PRA1 family protein adh_short PF00106.25 AAZ37263.1 - 9.6e-27 93.7 0.1 1.2e-26 93.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAZ37263.1 - 6.4e-22 78.3 0.1 7.7e-22 78.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 AAZ37263.1 - 7.4e-08 32.5 0.7 1.1e-07 31.9 0.7 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 AAZ37263.1 - 0.00012 21.7 0.4 0.00016 21.3 0.4 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 AAZ37263.1 - 0.00091 18.8 0.1 0.0016 17.9 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.15 AAZ37263.1 - 0.01 16.0 0.0 1.6 8.9 0.0 2.6 2 1 1 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase ADH_zinc_N PF00107.26 AAZ37263.1 - 0.02 14.9 0.3 0.067 13.2 0.1 1.9 2 0 0 2 2 2 0 Zinc-binding dehydrogenase RmlD_sub_bind PF04321.17 AAZ37263.1 - 0.031 13.4 0.1 0.041 13.0 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.8 AAZ37263.1 - 0.071 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase KR PF08659.10 AAZ37263.1 - 0.084 12.8 0.4 0.11 12.4 0.4 1.5 1 1 0 1 1 1 0 KR domain F420_oxidored PF03807.17 AAZ37263.1 - 0.11 13.0 0.0 0.31 11.6 0.0 1.6 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 AAZ37263.1 - 0.13 12.6 0.1 0.2 11.9 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Ribosomal_L1 PF00687.21 AAZ37264.1 - 3.5e-50 170.6 0.0 4.3e-50 170.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Rotamase_2 PF13145.6 AAZ37264.1 - 0.096 13.5 0.7 0.18 12.7 0.1 1.8 2 0 0 2 2 2 0 PPIC-type PPIASE domain DeoRC PF00455.22 AAZ37265.1 - 4.1e-51 173.1 0.6 5.6e-51 172.6 0.6 1.2 1 0 0 1 1 1 1 DeoR C terminal sensor domain HTH_DeoR PF08220.12 AAZ37265.1 - 2.1e-20 72.2 0.2 5.2e-20 70.9 0.2 1.7 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 AAZ37265.1 - 1.8e-07 31.0 0.3 4.1e-07 29.8 0.3 1.6 1 0 0 1 1 1 1 HTH domain MarR PF01047.22 AAZ37265.1 - 0.00074 19.4 0.0 0.0017 18.2 0.0 1.6 1 0 0 1 1 1 1 MarR family HTH_Crp_2 PF13545.6 AAZ37265.1 - 0.0018 18.2 0.6 0.054 13.5 0.1 2.6 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_20 PF12840.7 AAZ37265.1 - 0.0061 16.6 0.0 0.027 14.5 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain GntR PF00392.21 AAZ37265.1 - 0.0062 16.2 0.1 0.021 14.4 0.0 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family Sigma70_r4 PF04545.16 AAZ37265.1 - 0.01 15.4 0.1 0.025 14.1 0.1 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_Mga PF08280.11 AAZ37265.1 - 0.011 15.8 0.0 0.022 14.8 0.0 1.5 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain Put_DNA-bind_N PF06971.13 AAZ37265.1 - 0.016 15.2 0.0 0.033 14.2 0.0 1.6 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus MarR_2 PF12802.7 AAZ37265.1 - 0.017 15.0 0.1 0.031 14.2 0.1 1.4 1 0 0 1 1 1 0 MarR family Sigma70_r4_2 PF08281.12 AAZ37265.1 - 0.035 13.8 0.0 0.11 12.1 0.0 1.9 1 0 0 1 1 1 0 Sigma-70, region 4 CoA_trans PF01144.23 AAZ37265.1 - 0.069 12.5 0.1 0.099 12.0 0.1 1.3 1 0 0 1 1 1 0 Coenzyme A transferase NMO PF03060.15 AAZ37266.1 - 1.1e-74 251.8 0.4 1.2e-74 251.6 0.4 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 AAZ37266.1 - 1.6e-12 47.1 0.1 2.1e-06 27.0 0.0 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 AAZ37266.1 - 2.3e-08 33.5 9.2 2.4e-08 33.4 5.8 2.0 1 1 0 2 2 2 1 FMN-dependent dehydrogenase DUF561 PF04481.12 AAZ37266.1 - 3.2e-06 26.5 0.1 4.9e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF561) DHO_dh PF01180.21 AAZ37266.1 - 3.2e-06 26.6 0.1 4.8e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase His_biosynth PF00977.21 AAZ37266.1 - 5.2e-05 22.8 0.0 8e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 AAZ37266.1 - 0.0037 16.6 2.4 0.014 14.7 2.4 1.9 1 1 0 1 1 1 1 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.17 AAZ37266.1 - 0.0053 16.0 0.2 0.0077 15.4 0.2 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase NanE PF04131.14 AAZ37266.1 - 0.029 13.6 0.0 0.061 12.5 0.0 1.5 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Dus PF01207.17 AAZ37266.1 - 0.087 11.9 0.1 0.33 10.0 0.1 1.9 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) G3P_antiterm PF04309.12 AAZ37266.1 - 0.14 11.6 0.1 0.24 10.8 0.1 1.4 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator MS_channel PF00924.18 AAZ37267.1 - 4.7e-50 170.0 1.1 6.5e-50 169.5 1.1 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel TM_helix PF05552.12 AAZ37267.1 - 0.0012 18.7 0.4 0.0012 18.7 0.4 2.7 3 0 0 3 3 3 1 Conserved TM helix Methyltransf_11 PF08241.12 AAZ37268.1 - 7.6e-05 23.3 0.0 0.00012 22.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAZ37268.1 - 0.00048 20.0 0.0 0.0013 18.6 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain LamB_YcsF PF03746.16 AAZ37269.1 - 2.6e-100 335.0 0.0 2.9e-100 334.9 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family Amino_oxidase PF01593.24 AAZ37270.1 - 1.6e-23 83.8 0.4 2.1e-22 80.1 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 AAZ37270.1 - 7.5e-14 51.7 0.1 2.2e-13 50.2 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AAZ37270.1 - 3.5e-08 33.4 0.3 2.4e-06 27.4 0.2 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AAZ37270.1 - 0.0012 18.0 0.1 0.0019 17.4 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 AAZ37270.1 - 0.0033 18.0 0.1 0.02 15.5 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 AAZ37270.1 - 0.0035 15.8 0.0 0.0053 15.2 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 AAZ37270.1 - 0.0044 16.3 0.0 0.0081 15.4 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 AAZ37270.1 - 0.028 13.7 0.1 0.046 12.9 0.1 1.3 1 0 0 1 1 1 0 Thi4 family MCRA PF06100.11 AAZ37270.1 - 0.031 13.1 0.0 0.044 12.6 0.0 1.2 1 0 0 1 1 1 0 MCRA family HI0933_like PF03486.14 AAZ37270.1 - 0.24 10.1 0.0 0.87 8.2 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein PQQ PF01011.21 AAZ37271.1 - 0.00071 19.4 0.0 0.43 10.6 0.0 2.3 2 0 0 2 2 2 2 PQQ enzyme repeat HMA PF00403.26 AAZ37272.1 - 1.2e-10 41.7 0.0 1.5e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Heavy-metal-associated domain Nif11 PF07862.11 AAZ37272.1 - 0.023 15.0 0.0 0.031 14.6 0.0 1.4 1 1 0 1 1 1 0 Nif11 domain TusA PF01206.17 AAZ37272.1 - 0.14 12.0 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Sulfurtransferase TusA DUF2931 PF11153.8 AAZ37273.1 - 0.099 12.3 0.0 0.58 9.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2931) ABC_tran PF00005.27 AAZ37274.1 - 2e-29 102.8 0.0 2.5e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAZ37274.1 - 3.6e-05 23.7 0.0 0.14 12.0 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AAZ37274.1 - 0.00035 21.0 0.0 0.00047 20.6 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 AAZ37274.1 - 0.00051 20.0 0.0 0.00073 19.5 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_29 PF13555.6 AAZ37274.1 - 0.0023 17.6 0.0 0.0042 16.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AAZ37274.1 - 0.003 18.1 0.0 0.0045 17.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 AAZ37274.1 - 0.0038 16.8 0.0 0.01 15.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 AAZ37274.1 - 0.005 17.1 0.0 0.0086 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 AAZ37274.1 - 0.015 14.7 0.2 0.2 11.0 0.1 2.1 2 0 0 2 2 2 0 KaiC AAA_14 PF13173.6 AAZ37274.1 - 0.015 15.3 0.0 0.022 14.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 AAZ37274.1 - 0.017 15.5 0.0 0.024 15.1 0.0 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 AAZ37274.1 - 0.019 14.9 0.0 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase AAA_28 PF13521.6 AAZ37274.1 - 0.052 13.8 0.0 0.12 12.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 AAZ37274.1 - 0.06 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PRK PF00485.18 AAZ37274.1 - 0.077 12.7 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family SMC_N PF02463.19 AAZ37274.1 - 0.09 12.2 0.2 1.2 8.5 0.2 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain ATPase_2 PF01637.18 AAZ37274.1 - 0.13 12.1 0.0 0.19 11.7 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Sbt_1 PF05982.12 AAZ37274.1 - 0.16 11.2 0.0 0.22 10.7 0.0 1.1 1 0 0 1 1 1 0 Na+-dependent bicarbonate transporter superfamily AAA_24 PF13479.6 AAZ37274.1 - 0.19 11.5 0.1 0.26 11.0 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AAZ37274.1 - 0.19 11.4 0.0 0.3 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 AAZ37274.1 - 0.21 11.2 0.1 0.32 10.6 0.1 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC_ATPase PF09818.9 AAZ37274.1 - 0.43 9.3 0.9 3.1 6.5 0.1 2.0 2 0 0 2 2 2 0 Predicted ATPase of the ABC class BPD_transp_1 PF00528.22 AAZ37275.1 - 3.5e-42 144.2 11.5 3.5e-42 144.2 11.5 2.2 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Ni_hydr_CYTB PF01292.20 AAZ37275.1 - 4.5 6.8 8.5 14 5.2 8.2 2.1 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 LpxB PF02684.15 AAZ37276.1 - 4.1e-119 397.8 0.0 4.9e-119 397.5 0.0 1.0 1 0 0 1 1 1 1 Lipid-A-disaccharide synthetase DUF1902 PF08972.11 AAZ37276.1 - 0.16 12.0 0.5 20 5.2 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1902) MotA_ExbB PF01618.16 AAZ37277.1 - 9.6e-35 119.1 0.6 1.3e-34 118.6 0.6 1.2 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family DUF4777 PF16007.5 AAZ37277.1 - 0.039 14.2 0.1 0.36 11.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4777) EF_TS PF00889.19 AAZ37279.1 - 1.2e-53 181.8 2.7 2.2e-53 181.0 2.7 1.4 1 0 0 1 1 1 1 Elongation factor TS Peptidase_M22 PF00814.25 AAZ37279.1 - 0.011 15.4 0.4 0.018 14.7 0.4 1.4 1 0 0 1 1 1 0 Glycoprotease family GFP PF01353.22 AAZ37279.1 - 0.092 12.2 0.0 0.17 11.3 0.0 1.4 1 1 0 1 1 1 0 Green fluorescent protein AMP-binding_C PF13193.6 AAZ37279.1 - 0.27 12.2 2.6 3.1 8.8 0.0 3.1 3 0 0 3 3 3 0 AMP-binding enzyme C-terminal domain Ribosomal_L12 PF00542.19 AAZ37279.1 - 1.5 9.2 9.7 0.11 12.8 1.9 3.0 3 0 0 3 3 3 0 Ribosomal protein L7/L12 C-terminal domain CTP_transf_like PF01467.26 AAZ37280.1 - 2.8e-29 102.1 0.0 3.4e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like Na_H_antiport_1 PF06965.12 AAZ37281.1 - 2.2e-147 490.8 27.0 2.5e-147 490.7 27.0 1.0 1 0 0 1 1 1 1 Na+/H+ antiporter 1 ABC_tran PF00005.27 AAZ37282.1 - 1.4e-36 126.1 0.0 2e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAZ37282.1 - 4.1e-08 33.4 0.1 0.00061 19.7 0.1 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system TOBE_2 PF08402.10 AAZ37282.1 - 2.1e-07 31.0 0.3 3.3e-06 27.2 0.0 2.9 3 0 0 3 3 3 1 TOBE domain AAA_16 PF13191.6 AAZ37282.1 - 0.0002 21.8 0.9 0.00091 19.6 0.9 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AAZ37282.1 - 0.001 19.3 0.3 0.0087 16.3 0.3 2.2 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 AAZ37282.1 - 0.0035 17.8 0.1 0.035 14.5 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 AAZ37282.1 - 0.0062 16.5 0.0 0.01 15.8 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain SMC_N PF02463.19 AAZ37282.1 - 0.007 15.8 0.0 0.22 10.9 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 AAZ37282.1 - 0.02 15.1 0.2 0.31 11.3 0.2 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 AAZ37282.1 - 0.036 14.3 0.0 0.15 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 AAZ37282.1 - 0.054 14.0 0.1 0.085 13.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 AAZ37282.1 - 0.1 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 AAZ37282.1 - 0.12 12.3 0.2 0.44 10.4 0.0 2.0 2 0 0 2 2 2 0 NACHT domain ATP-synt_ab PF00006.25 AAZ37282.1 - 0.17 11.5 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Bestrophin PF01062.21 AAZ37283.1 - 4.4e-35 121.5 0.1 5.3e-35 121.2 0.1 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Aldo_ket_red PF00248.21 AAZ37284.1 - 2.9e-75 253.2 0.0 3.4e-75 253.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Zip PF02535.22 AAZ37286.1 - 3.2e-29 102.2 26.7 3.6e-27 95.5 9.2 2.1 2 0 0 2 2 2 2 ZIP Zinc transporter DUF2613 PF11021.8 AAZ37286.1 - 0.022 14.9 5.1 5.3 7.2 0.0 4.3 3 1 1 4 4 4 0 Protein of unknown function (DUF2613) TPIP1 PF15338.6 AAZ37286.1 - 0.21 11.6 2.3 0.25 11.4 0.5 2.0 2 0 0 2 2 2 0 p53-regulated apoptosis-inducing protein 1 BAGE PF08180.11 AAZ37286.1 - 0.3 11.2 3.5 0.95 9.6 3.5 1.9 1 0 0 1 1 1 0 B melanoma antigen family Phenol_MetA_deg PF13557.6 AAZ37287.1 - 2.2e-58 198.1 10.6 2.7e-58 197.8 10.6 1.1 1 0 0 1 1 1 1 Putative MetA-pathway of phenol degradation BBP2 PF07642.11 AAZ37287.1 - 0.007 15.6 1.9 0.019 14.2 1.9 1.7 1 1 0 1 1 1 1 Putative beta-barrel porin-2, OmpL-like. bbp2 Porin_OmpG_1_2 PF16946.5 AAZ37287.1 - 0.026 13.8 0.1 0.048 12.9 0.1 1.4 1 0 0 1 1 1 0 OMPG-porin 1 family KdgM PF06178.13 AAZ37287.1 - 0.044 13.4 0.4 0.044 13.4 0.4 1.6 2 0 0 2 2 2 0 Oligogalacturonate-specific porin protein (KdgM) DUF2514 PF10721.9 AAZ37288.1 - 0.0034 17.4 8.7 0.0039 17.2 8.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2514) Spore_III_AB PF09548.10 AAZ37288.1 - 0.021 15.0 0.1 0.028 14.5 0.1 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) AAA_lid_6 PF17866.1 AAZ37288.1 - 0.026 14.7 0.8 0.044 14.0 0.8 1.5 1 1 0 1 1 1 0 AAA lid domain SHR3_chaperone PF08229.11 AAZ37288.1 - 0.037 13.0 0.6 0.054 12.5 0.6 1.5 1 1 0 1 1 1 0 ER membrane protein SH3 DUF4131 PF13567.6 AAZ37288.1 - 0.057 13.1 0.1 0.057 13.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Synaptobrevin PF00957.21 AAZ37288.1 - 0.57 10.0 5.2 2.7 7.9 0.5 2.1 2 0 0 2 2 2 0 Synaptobrevin Alanine_zipper PF11839.8 AAZ37288.1 - 1.9 8.9 22.4 7.9 6.9 22.4 1.9 1 1 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein OEP PF02321.18 AAZ37289.1 - 3.5e-56 190.0 20.9 8.4e-30 104.0 4.1 2.0 2 0 0 2 2 2 2 Outer membrane efflux protein Hydrolase_4 PF12146.8 AAZ37290.1 - 8.6e-10 38.3 0.0 3.7e-08 32.9 0.0 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AAZ37290.1 - 0.00038 20.2 0.1 0.23 11.1 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAZ37290.1 - 0.0054 17.4 1.6 0.0068 17.0 1.4 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 AAZ37290.1 - 0.025 14.4 0.0 0.16 11.7 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 AAZ37290.1 - 0.03 14.2 0.0 0.056 13.3 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.18 AAZ37290.1 - 0.052 13.1 0.0 8.9 5.8 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 AAZ37290.1 - 0.16 11.8 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Redoxin PF08534.10 AAZ37291.1 - 4.1e-16 59.0 0.0 5e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 AAZ37291.1 - 6.6e-14 51.9 0.0 9.2e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin PF00085.20 AAZ37291.1 - 0.0034 17.4 0.0 0.0076 16.2 0.0 1.5 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 AAZ37291.1 - 0.0098 16.3 0.0 0.019 15.4 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 AAZ37291.1 - 0.034 14.5 0.0 0.098 13.0 0.0 1.8 1 1 0 1 1 1 0 Thioredoxin-like AA_kinase PF00696.28 AAZ37292.1 - 3.8e-51 174.0 2.7 7.1e-51 173.1 2.7 1.4 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.6 AAZ37292.1 - 4.5e-20 71.2 0.8 4.1e-15 55.3 0.4 2.9 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 AAZ37292.1 - 4.4e-19 68.0 2.0 5.3e-11 42.1 0.1 3.2 3 0 0 3 3 3 2 ACT domain DUF3335 PF11814.8 AAZ37292.1 - 0.012 15.1 1.5 0.23 10.9 0.0 2.8 3 0 0 3 3 3 0 Peptidase_C39 like family SIS PF01380.22 AAZ37292.1 - 0.016 15.0 1.8 1.4 8.8 0.0 3.5 3 1 1 4 4 4 0 SIS domain HlyD_3 PF13437.6 AAZ37294.1 - 3.4e-13 50.2 2.4 8.6e-09 36.1 0.1 2.8 2 2 0 2 2 2 2 HlyD family secretion protein HlyD PF00529.20 AAZ37294.1 - 2.6e-09 36.9 0.0 7e-09 35.5 0.0 1.8 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl_2 PF13533.6 AAZ37294.1 - 5.7e-09 35.7 1.1 2.3e-08 33.7 0.4 2.5 2 0 0 2 2 2 1 Biotin-lipoyl like Myosin_tail_1 PF01576.19 AAZ37294.1 - 0.0019 16.1 9.2 0.0027 15.6 9.2 1.1 1 0 0 1 1 1 1 Myosin tail Biotin_lipoyl PF00364.22 AAZ37294.1 - 0.0027 17.5 0.2 0.017 15.0 0.1 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme HlyD_D23 PF16576.5 AAZ37294.1 - 0.022 14.0 13.1 2.6e+02 0.7 13.1 3.4 1 1 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion PH_13 PF16652.5 AAZ37294.1 - 0.11 12.3 0.5 0.19 11.5 0.5 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain Autotransporter PF03797.19 AAZ37295.1 - 2.3e-64 217.5 19.1 2.3e-64 217.5 19.1 4.8 5 2 1 6 6 6 1 Autotransporter beta-domain Trypan_PARP PF05887.11 AAZ37295.1 - 1.1e-10 41.7 13.1 2.6e-10 40.4 13.1 1.6 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) TonB_N PF16031.5 AAZ37295.1 - 0.19 12.3 29.6 0.34 11.4 29.6 1.3 1 0 0 1 1 1 0 TonB polyproline region TcA_TcB_BD PF18276.1 AAZ37296.1 - 2.2e-63 214.0 0.0 3.8e-63 213.3 0.0 1.4 1 0 0 1 1 1 1 Tc toxin complex TcA C-terminal TcB-binding domain AlaDh_PNT_C PF01262.21 AAZ37296.1 - 0.032 13.5 0.4 0.078 12.3 0.4 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 4HBT_3 PF13622.6 AAZ37297.1 - 6.7e-47 160.8 1.9 7.6e-47 160.7 1.9 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily PD40 PF07676.12 AAZ37297.1 - 0.13 12.3 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat 4HBT PF03061.22 AAZ37297.1 - 0.14 12.5 0.0 0.49 10.8 0.0 1.9 2 0 0 2 2 2 0 Thioesterase superfamily Gate PF07670.14 AAZ37298.1 - 1.9e-12 47.4 7.3 1.3e-07 31.9 0.5 3.7 3 1 0 3 3 3 2 Nucleoside recognition ABC_tran PF00005.27 AAZ37299.1 - 3.8e-27 95.5 0.0 5.3e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAZ37299.1 - 1.4e-07 31.7 0.5 0.00045 20.1 0.1 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system BCA_ABC_TP_C PF12399.8 AAZ37299.1 - 4.4e-07 29.7 0.1 7.3e-07 29.0 0.1 1.4 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_23 PF13476.6 AAZ37299.1 - 2.2e-05 25.0 1.5 2.7e-05 24.7 0.2 1.7 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 AAZ37299.1 - 3.1e-05 23.5 0.1 0.00015 21.2 0.1 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 AAZ37299.1 - 0.0005 19.9 0.1 0.00099 18.9 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AAZ37299.1 - 0.0011 18.7 0.0 0.0024 17.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AAZ37299.1 - 0.0053 17.0 0.7 0.087 13.1 0.7 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AAZ37299.1 - 0.015 15.1 0.4 0.054 13.2 0.4 2.0 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 AAZ37299.1 - 0.025 14.6 0.0 0.05 13.7 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 AAZ37299.1 - 0.057 13.3 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_13 PF13166.6 AAZ37299.1 - 0.061 12.0 0.0 0.077 11.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 AAZ37299.1 - 0.074 13.5 0.0 0.18 12.3 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AAZ37299.1 - 0.095 13.1 0.1 0.18 12.2 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain ATP-synt_ab PF00006.25 AAZ37299.1 - 0.099 12.3 0.0 0.2 11.3 0.0 1.6 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_27 PF13514.6 AAZ37299.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 AAZ37299.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase IPPT PF01715.17 AAZ37300.1 - 1.9e-86 289.6 0.0 2.3e-86 289.3 0.0 1.0 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 AAZ37300.1 - 5.2e-06 26.0 0.0 0.0009 18.7 0.0 2.2 2 0 0 2 2 2 2 Isopentenyl transferase AAA_33 PF13671.6 AAZ37300.1 - 4.3e-05 23.7 0.0 0.00053 20.2 0.0 2.5 1 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 AAZ37300.1 - 0.07 13.7 0.0 0.15 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Pyr_redox_2 PF07992.14 AAZ37301.1 - 1.2e-25 90.4 0.0 1.7e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SO_alpha_A3 PF17806.1 AAZ37301.1 - 4.6e-11 42.9 0.0 9.2e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Sarcosine oxidase A3 domain Fer2_BFD PF04324.15 AAZ37301.1 - 9.6e-10 38.7 4.7 1.8e-09 37.8 4.7 1.5 1 0 0 1 1 1 1 BFD-like [2Fe-2S] binding domain FAD_binding_3 PF01494.19 AAZ37301.1 - 8.7e-06 25.2 0.1 1.5e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 AAZ37301.1 - 4.5e-05 22.3 1.3 0.0011 17.7 0.4 2.4 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 AAZ37301.1 - 7.5e-05 22.9 0.2 7.5e-05 22.9 0.2 3.0 4 0 0 4 4 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 AAZ37301.1 - 0.00039 19.8 0.4 0.0037 16.6 0.4 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AAZ37301.1 - 0.00074 18.7 1.7 0.0023 17.1 0.6 2.2 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 AAZ37301.1 - 0.0019 17.5 0.4 0.0046 16.2 0.1 1.8 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 AAZ37301.1 - 0.0029 17.0 0.4 0.0029 17.0 0.4 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 AAZ37301.1 - 0.0073 16.8 2.0 0.35 11.5 0.3 3.7 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AAZ37301.1 - 0.015 14.4 0.2 0.015 14.4 0.2 2.3 3 0 0 3 3 3 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 AAZ37301.1 - 0.019 15.0 1.7 0.037 14.0 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 AAZ37301.1 - 0.039 13.0 0.4 0.088 11.8 0.4 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 AAZ37301.1 - 0.059 13.8 0.0 0.18 12.2 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 AAZ37301.1 - 0.07 12.4 1.6 0.74 9.1 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 AAZ37301.1 - 0.099 12.7 0.1 0.41 10.7 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 AAZ37301.1 - 0.14 12.0 1.0 1 9.2 0.0 2.5 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 AAZ37301.1 - 0.46 10.0 7.8 4.2 6.8 7.8 2.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase DUF4148 PF13663.6 AAZ37302.1 - 0.03 14.5 0.4 0.078 13.2 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) Acetyltransf_1 PF00583.25 AAZ37303.1 - 3.9e-15 56.1 0.0 4.8e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AAZ37303.1 - 5.6e-13 48.9 0.0 7.1e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AAZ37303.1 - 2.9e-11 43.7 0.0 3.4e-11 43.5 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAZ37303.1 - 5.7e-11 42.7 0.0 8.4e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AAZ37303.1 - 1.8e-09 38.4 0.0 2.1e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAZ37303.1 - 5.3e-07 29.5 0.1 8.9e-07 28.8 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 AAZ37303.1 - 1.3e-05 25.2 0.1 1.9e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AAZ37303.1 - 0.00043 20.4 0.0 0.00074 19.6 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase PanZ PF12568.8 AAZ37303.1 - 0.0043 16.8 0.0 0.0067 16.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_8 PF13523.6 AAZ37303.1 - 0.052 13.2 0.0 0.089 12.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-dskA_traR PF01258.17 AAZ37304.1 - 1.8e-07 31.0 0.5 1.8e-07 31.0 0.5 1.8 2 0 0 2 2 2 1 Prokaryotic dksA/traR C4-type zinc finger DZR PF12773.7 AAZ37304.1 - 0.013 15.5 1.0 0.018 15.0 1.0 1.3 1 0 0 1 1 1 0 Double zinc ribbon DUF1329 PF07044.11 AAZ37305.1 - 3e-145 484.1 4.1 3.5e-145 483.9 4.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1329) LolA_like PF17131.4 AAZ37305.1 - 8.3e-07 28.9 0.1 0.00012 21.9 0.1 2.4 1 1 0 1 1 1 1 Outer membrane lipoprotein-sorting protein NMT1_2 PF13379.6 AAZ37306.1 - 3e-22 79.6 0.0 3.9e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 NMT1-like family Lipoprotein_9 PF03180.14 AAZ37306.1 - 4.9e-05 22.6 0.1 0.0011 18.1 0.0 2.1 2 0 0 2 2 2 1 NLPA lipoprotein OpuAC PF04069.12 AAZ37306.1 - 0.0082 15.7 0.6 0.046 13.3 0.1 2.0 2 0 0 2 2 2 1 Substrate binding domain of ABC-type glycine betaine transport system NMT1 PF09084.11 AAZ37306.1 - 0.01 15.8 0.0 0.042 13.8 0.0 1.8 1 1 0 1 1 1 0 NMT1/THI5 like rpo30_N PF12410.8 AAZ37307.1 - 0.089 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Poxvirus DNA dependent RNA polymerase 30kDa subunit Sel1 PF08238.12 AAZ37308.1 - 2.2e-05 25.0 10.5 0.0034 18.0 0.1 5.5 5 1 0 5 5 5 1 Sel1 repeat TPR_17 PF13431.6 AAZ37308.1 - 0.0054 17.0 4.1 17 6.1 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat HHA PF05321.11 AAZ37308.1 - 0.047 14.0 0.3 0.23 11.8 0.0 2.2 2 0 0 2 2 2 0 Haemolysin expression modulating protein TPR_16 PF13432.6 AAZ37308.1 - 1 10.1 22.9 0.17 12.5 8.0 4.7 3 2 1 4 4 4 0 Tetratricopeptide repeat Aminotran_5 PF00266.19 AAZ37309.1 - 5.7e-83 278.9 0.1 6.6e-83 278.7 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 AAZ37309.1 - 1.6e-05 24.3 0.1 2.2e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 AAZ37309.1 - 9.2e-05 21.9 0.1 0.00013 21.5 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 AAZ37309.1 - 0.00025 19.7 0.0 0.0004 19.0 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Bac_luciferase PF00296.20 AAZ37311.1 - 4.4e-66 223.5 9.0 5.8e-66 223.1 9.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase ETF PF01012.21 AAZ37311.1 - 0.19 11.6 2.0 4.7 7.1 0.2 2.4 2 0 0 2 2 2 0 Electron transfer flavoprotein domain DNA_topoisoIV PF00521.20 AAZ37312.1 - 1.2e-151 505.5 0.0 1.5e-151 505.1 0.0 1.1 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.13 AAZ37312.1 - 6.1e-75 246.5 8.9 1.4e-14 53.3 0.1 6.6 7 0 0 7 7 7 6 DNA gyrase C-terminal domain, beta-propeller Metal_hydrol PF10118.9 AAZ37313.1 - 1e-57 195.7 0.4 1.2e-57 195.5 0.4 1.0 1 0 0 1 1 1 1 Predicted metal-dependent hydrolase DUF3225 PF11533.8 AAZ37314.1 - 1.3e-50 170.4 0.2 1.5e-50 170.1 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3225) DUF4440 PF14534.6 AAZ37314.1 - 0.0002 21.7 0.4 0.00025 21.4 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 AAZ37314.1 - 0.05 13.9 0.4 0.08 13.2 0.4 1.4 1 1 0 1 1 1 0 SnoaL-like domain CaMKII_AD PF08332.10 AAZ37314.1 - 0.14 12.3 0.1 0.18 11.9 0.1 1.5 1 1 0 1 1 1 0 Calcium/calmodulin dependent protein kinase II association domain LPAM_2 PF13627.6 AAZ37315.1 - 1.3e-09 37.6 5.6 1.7e-09 37.2 5.6 1.2 1 0 0 1 1 1 1 Prokaryotic lipoprotein-attachment site DUF4148 PF13663.6 AAZ37315.1 - 0.082 13.1 0.0 0.091 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) Acyl-CoA_dh_2 PF08028.11 AAZ37316.1 - 1.8e-06 28.3 0.2 2.3e-06 27.9 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_1 PF00441.24 AAZ37316.1 - 0.00015 22.0 0.0 0.00022 21.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain TetR_C_22 PF17928.1 AAZ37316.1 - 0.037 14.4 0.1 0.062 13.6 0.1 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain HAP PF03866.13 AAZ37318.1 - 0.013 15.5 0.1 0.018 15.0 0.1 1.2 1 0 0 1 1 1 0 Hydrophobic abundant protein (HAP) LPAM_1 PF08139.12 AAZ37318.1 - 0.68 10.5 6.3 0.32 11.6 1.1 2.4 2 0 0 2 2 2 0 Prokaryotic membrane lipoprotein lipid attachment site SfsA PF03749.13 AAZ37319.1 - 1.6e-46 157.7 0.0 1.9e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 Sugar fermentation stimulation protein RE domain SfsA_N PF17746.1 AAZ37319.1 - 1.2e-20 73.4 0.0 7e-20 71.0 0.0 2.1 1 1 1 2 2 2 1 SfsA N-terminal OB domain MannoseP_isomer PF01050.18 AAZ37320.1 - 5.1e-70 234.2 0.4 8.8e-70 233.4 0.4 1.4 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase NTP_transferase PF00483.23 AAZ37320.1 - 1.5e-65 221.3 0.0 1.1e-64 218.4 0.0 1.9 2 0 0 2 2 2 1 Nucleotidyl transferase Cupin_2 PF07883.11 AAZ37320.1 - 2.4e-11 43.2 0.0 8.3e-11 41.5 0.0 2.0 1 0 0 1 1 1 1 Cupin domain NTP_transf_3 PF12804.7 AAZ37320.1 - 1.5e-09 38.4 0.2 1.5e-09 38.4 0.2 1.8 2 0 0 2 2 2 1 MobA-like NTP transferase domain Gti1_Pac2 PF09729.9 AAZ37320.1 - 0.052 13.7 0.1 0.08 13.0 0.1 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family DUF1289 PF06945.13 AAZ37321.1 - 1.7e-15 56.6 0.2 2.9e-15 55.8 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1289) Response_reg PF00072.24 AAZ37322.1 - 6.8e-18 64.9 0.2 1e-17 64.3 0.2 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AAZ37322.1 - 1.4e-15 56.6 0.0 2.8e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AAZ37322.1 - 2.6e-07 30.2 0.0 5.1e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAZ37322.1 - 0.00021 20.8 0.0 0.00077 18.9 0.0 2.0 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_28 PF13518.6 AAZ37322.1 - 0.0012 19.0 0.0 0.012 15.7 0.0 2.3 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 AAZ37322.1 - 0.0021 17.8 0.1 0.025 14.4 0.0 2.5 2 1 1 3 3 3 1 Homeodomain-like domain HTH_38 PF13936.6 AAZ37322.1 - 0.0094 15.7 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain DUF2089 PF09862.9 AAZ37322.1 - 0.041 13.9 0.0 0.19 11.8 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2089) HTH_10 PF04967.12 AAZ37322.1 - 0.046 13.5 0.1 0.95 9.3 0.0 2.6 2 1 0 2 2 2 0 HTH DNA binding domain HTH_Tnp_1 PF01527.20 AAZ37322.1 - 0.06 13.7 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Transposase HTH_24 PF13412.6 AAZ37322.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding LexA_DNA_bind PF01726.16 AAZ37322.1 - 0.14 11.9 0.2 1.4 8.8 0.2 2.5 1 1 0 1 1 1 0 LexA DNA binding domain HTH_7 PF02796.15 AAZ37322.1 - 0.17 12.0 0.0 0.62 10.2 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase GHMP_kinases_N PF00288.26 AAZ37323.1 - 5.2e-12 45.8 0.0 9.4e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 AAZ37323.1 - 9.5e-07 29.1 0.0 2.1e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal RMF PF04957.12 AAZ37324.1 - 1.1e-25 89.6 0.9 1.1e-25 89.6 0.9 1.7 2 0 0 2 2 2 1 Ribosome modulation factor CheB_methylest PF01339.17 AAZ37325.1 - 7.2e-54 182.0 0.1 1.8e-53 180.8 0.0 1.7 2 0 0 2 2 2 1 CheB methylesterase Response_reg PF00072.24 AAZ37325.1 - 1.8e-16 60.3 0.8 4.4e-16 59.0 0.6 1.7 2 0 0 2 2 2 1 Response regulator receiver domain Glycos_transf_1 PF00534.20 AAZ37326.1 - 5.3e-16 58.6 0.0 7.9e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAZ37326.1 - 4.9e-12 46.4 0.0 1.6e-11 44.8 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAZ37326.1 - 1.1e-05 25.5 0.2 6.6e-05 23.0 0.2 2.2 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 AAZ37326.1 - 0.00015 22.1 0.0 0.00033 21.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 AAZ37326.1 - 0.00023 21.6 11.3 0.0011 19.5 9.2 2.7 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain CTP_synth_N PF06418.14 AAZ37327.1 - 1.8e-124 414.3 0.0 2.9e-124 413.7 0.0 1.3 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 AAZ37327.1 - 8.4e-59 198.5 0.0 1.6e-58 197.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AAZ37327.1 - 1.7e-08 34.5 0.5 8.8e-08 32.2 0.1 2.4 2 2 0 2 2 2 1 Peptidase C26 CbiA PF01656.23 AAZ37327.1 - 0.00078 19.5 0.0 0.0014 18.7 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Gln-synt_C PF00120.24 AAZ37328.1 - 2.2e-137 457.7 0.0 2.6e-137 457.4 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 AAZ37328.1 - 2.9e-29 100.6 0.2 5.3e-29 99.8 0.2 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain DDE_Tnp_IS66 PF03050.14 AAZ37329.1 - 1e-56 192.5 0.0 1.3e-56 192.2 0.0 1.1 1 0 0 1 1 1 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 AAZ37329.1 - 6.1e-17 61.6 0.5 1.1e-16 60.8 0.5 1.4 1 0 0 1 1 1 1 IS66 C-terminal element TnpB_IS66 PF05717.13 AAZ37329.1 - 5.7e-08 32.6 0.0 9.9e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 IS66 Orf2 like protein Response_reg PF00072.24 AAZ37330.1 - 3.7e-26 91.5 0.2 5.5e-26 90.9 0.2 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AAZ37330.1 - 1.7e-15 56.3 0.0 3e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AAZ37330.1 - 2e-05 24.2 0.3 2e-05 24.2 0.3 2.0 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_40 PF14493.6 AAZ37330.1 - 0.0017 18.7 0.2 0.015 15.7 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 AAZ37330.1 - 0.0024 17.6 0.3 0.0096 15.7 0.1 2.2 1 1 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.6 AAZ37330.1 - 0.0045 16.7 0.3 0.014 15.1 0.3 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain DUF3368 PF11848.8 AAZ37330.1 - 0.0052 16.5 0.1 0.045 13.5 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3368) Sigma70_r4 PF04545.16 AAZ37330.1 - 0.012 15.1 1.5 0.012 15.1 1.5 1.8 2 0 0 2 2 2 0 Sigma-70, region 4 Trp_repressor PF01371.19 AAZ37330.1 - 0.015 15.4 0.4 0.047 13.8 0.4 1.8 1 1 0 1 1 1 0 Trp repressor protein CheB_methylest PF01339.17 AAZ37330.1 - 0.044 13.5 0.0 0.099 12.4 0.0 1.5 2 0 0 2 2 2 0 CheB methylesterase LexA_DNA_bind PF01726.16 AAZ37330.1 - 0.045 13.5 0.4 0.37 10.6 0.4 2.4 1 1 0 1 1 1 0 LexA DNA binding domain HTH_24 PF13412.6 AAZ37330.1 - 0.059 13.0 1.3 0.1 12.2 0.3 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 AAZ37330.1 - 0.09 12.9 1.2 1.1 9.4 0.1 2.9 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_10 PF04967.12 AAZ37330.1 - 0.11 12.3 0.9 3.4 7.6 0.9 2.7 1 1 0 1 1 1 0 HTH DNA binding domain KORA PF16509.5 AAZ37330.1 - 0.15 12.3 0.1 0.33 11.3 0.1 1.5 1 0 0 1 1 1 0 TrfB plasmid transcriptional repressor PseudoU_synth_1 PF01416.20 AAZ37331.1 - 8.2e-40 135.6 2.2 5.8e-30 103.9 0.1 2.4 3 0 0 3 3 3 2 tRNA pseudouridine synthase PTS_EIIA_2 PF00359.22 AAZ37332.1 - 2.3e-35 121.6 0.0 2.6e-35 121.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 Band_3_cyto PF07565.13 AAZ37332.1 - 0.00029 20.7 0.0 0.00044 20.1 0.0 1.2 1 0 0 1 1 1 1 Band 3 cytoplasmic domain BON PF04972.17 AAZ37333.1 - 1.7e-27 95.5 5.3 6.9e-16 58.3 0.2 2.1 2 0 0 2 2 2 2 BON domain AcetylCoA_hyd_C PF13336.6 AAZ37333.1 - 0.04 13.8 0.1 7.6 6.5 0.0 2.2 1 1 1 2 2 2 0 Acetyl-CoA hydrolase/transferase C-terminal domain Aminotran_1_2 PF00155.21 AAZ37334.1 - 6.6e-25 88.0 0.0 1.6e-24 86.8 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II GntR PF00392.21 AAZ37334.1 - 1.6e-18 66.1 0.6 9.2e-18 63.7 0.1 2.6 3 0 0 3 3 3 1 Bacterial regulatory proteins, gntR family Aminotran_MocR PF12897.7 AAZ37334.1 - 0.00016 20.6 0.0 0.00035 19.5 0.0 1.7 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Fe_dep_repress PF01325.19 AAZ37334.1 - 0.0019 18.4 0.6 0.0041 17.3 0.0 1.9 2 0 0 2 2 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_50 PF18024.1 AAZ37334.1 - 0.0058 16.2 0.1 0.014 15.0 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 AAZ37334.1 - 0.011 15.7 0.1 0.048 13.6 0.0 2.2 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_41 PF14502.6 AAZ37334.1 - 0.013 15.2 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_11 PF08279.12 AAZ37334.1 - 0.014 15.3 0.0 0.074 13.0 0.0 2.2 2 0 0 2 2 2 0 HTH domain MarR_2 PF12802.7 AAZ37334.1 - 0.028 14.3 0.0 0.082 12.8 0.0 1.8 1 0 0 1 1 1 0 MarR family HTH_24 PF13412.6 AAZ37334.1 - 0.065 12.8 0.0 0.19 11.3 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR PF01047.22 AAZ37334.1 - 0.09 12.7 0.0 0.8 9.7 0.0 2.4 3 0 0 3 3 3 0 MarR family TrmB PF01978.19 AAZ37334.1 - 0.094 12.6 0.1 0.4 10.6 0.0 2.0 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_36 PF13730.6 AAZ37334.1 - 0.1 12.5 0.0 0.32 11.0 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain Iso_dh PF00180.20 AAZ37335.1 - 3.9e-88 295.9 0.0 4.8e-88 295.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF166 PF02593.14 AAZ37335.1 - 0.084 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF4875 PF16175.5 AAZ37335.1 - 0.15 12.2 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4875) LysR_substrate PF03466.20 AAZ37336.1 - 1.1e-13 51.1 3.7 1.3e-13 50.8 3.7 1.0 1 0 0 1 1 1 1 LysR substrate binding domain DUF2322 PF10084.9 AAZ37336.1 - 0.14 12.2 0.1 1 9.5 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2322) DUF4096 PF13340.6 AAZ37337.1 - 5.9e-25 87.3 0.4 1.5e-24 86.0 0.4 1.7 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1 PF01609.21 AAZ37337.1 - 5.5e-14 52.3 0.0 9.7e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AAZ37337.1 - 2.4e-08 34.2 0.1 7.4e-08 32.7 0.1 1.9 1 0 0 1 1 1 1 Transposase DDE domain HTH_Tnp_Tc3_2 PF01498.18 AAZ37337.1 - 0.063 13.5 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Transposase Arabinose_bd PF12625.7 AAZ37338.1 - 1.1e-40 139.7 0.8 1.5e-40 139.2 0.8 1.2 1 0 0 1 1 1 1 Arabinose-binding domain of AraC transcription regulator, N-term HTH_18 PF12833.7 AAZ37338.1 - 8.1e-16 58.1 0.7 8.1e-16 58.1 0.7 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAZ37338.1 - 1.1e-09 38.1 0.0 1.6e-06 28.0 0.0 2.5 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_Tnp_ISL3 PF13542.6 AAZ37338.1 - 0.046 13.1 0.2 0.36 10.3 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_8 PF02954.19 AAZ37338.1 - 0.054 13.3 0.0 0.22 11.3 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family HlyD_3 PF13437.6 AAZ37340.1 - 2.3e-14 54.0 2.3 8.1e-12 45.8 0.0 3.6 3 1 1 4 4 4 1 HlyD family secretion protein HlyD_D23 PF16576.5 AAZ37340.1 - 5.8e-13 48.6 9.7 2.9e-12 46.3 7.7 2.5 2 1 0 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 AAZ37340.1 - 2.4e-09 36.9 8.7 3.1e-09 36.5 0.5 3.7 3 0 0 3 3 3 1 Biotin-lipoyl like HlyD PF00529.20 AAZ37340.1 - 7.7e-07 28.9 0.0 1.4e-06 28.1 0.0 1.6 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl PF00364.22 AAZ37340.1 - 0.018 14.8 0.0 2.2 8.2 0.0 2.7 2 0 0 2 2 2 0 Biotin-requiring enzyme Spc7 PF08317.11 AAZ37340.1 - 1.1 8.0 7.1 1.6 7.6 7.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein ABC_tran PF00005.27 AAZ37341.1 - 5e-26 91.8 0.0 1.8e-25 90.1 0.0 1.8 1 1 0 1 1 1 1 ABC transporter BCA_ABC_TP_C PF12399.8 AAZ37341.1 - 7.3e-10 38.5 0.5 1.4e-09 37.7 0.5 1.5 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_21 PF13304.6 AAZ37341.1 - 5.9e-09 36.2 0.1 0.00044 20.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AAZ37341.1 - 1.2e-05 25.9 0.1 1.8e-05 25.3 0.1 1.3 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 AAZ37341.1 - 0.00012 22.1 0.1 0.00024 21.2 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase SMC_N PF02463.19 AAZ37341.1 - 0.00025 20.6 0.1 0.17 11.3 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AAZ37341.1 - 0.00071 19.9 0.1 0.023 15.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 AAZ37341.1 - 0.0022 17.7 0.3 0.02 14.6 0.1 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 AAZ37341.1 - 0.0058 16.3 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 AAZ37341.1 - 0.006 16.3 0.0 0.015 15.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain FeoB_N PF02421.18 AAZ37341.1 - 0.016 14.7 0.0 0.031 13.8 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B SRP54 PF00448.22 AAZ37341.1 - 0.018 14.7 0.1 0.034 13.8 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 AAZ37341.1 - 0.019 14.8 0.1 0.031 14.2 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase IstB_IS21 PF01695.17 AAZ37341.1 - 0.022 14.5 0.2 6.1 6.5 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein Rad17 PF03215.15 AAZ37341.1 - 0.079 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_16 PF13191.6 AAZ37341.1 - 0.12 12.7 0.1 0.21 12.0 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_27 PF13514.6 AAZ37341.1 - 0.15 11.6 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AAZ37341.1 - 0.18 11.4 0.1 5.6 6.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain IclR PF01614.18 AAZ37342.1 - 2.4e-15 56.5 0.0 6.6e-15 55.1 0.0 1.7 1 1 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 AAZ37342.1 - 2.4e-11 43.3 0.7 4.9e-11 42.2 0.7 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_Crp_2 PF13545.6 AAZ37342.1 - 0.012 15.5 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain MarR_2 PF12802.7 AAZ37342.1 - 0.025 14.4 0.3 0.064 13.2 0.3 1.6 1 0 0 1 1 1 0 MarR family Tex_N PF09371.10 AAZ37343.1 - 3.2e-68 229.0 0.4 6.5e-68 228.0 0.4 1.5 1 0 0 1 1 1 1 Tex-like protein N-terminal domain Tex_YqgF PF16921.5 AAZ37343.1 - 3.3e-54 182.7 0.0 6.1e-54 181.8 0.0 1.5 1 0 0 1 1 1 1 Tex protein YqgF-like domain HHH_3 PF12836.7 AAZ37343.1 - 2.8e-28 98.0 0.2 8e-28 96.5 0.2 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_9 PF17674.1 AAZ37343.1 - 7.2e-26 90.9 0.0 2.5e-25 89.2 0.0 2.0 1 0 0 1 1 1 1 HHH domain S1 PF00575.23 AAZ37343.1 - 5.7e-19 68.2 1.3 1.1e-18 67.3 1.3 1.5 1 0 0 1 1 1 1 S1 RNA binding domain YqgF PF14639.6 AAZ37343.1 - 1.5e-06 28.1 0.0 3.2e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.6 AAZ37343.1 - 1.6e-05 25.2 0.0 3.3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif T2SSK PF03934.13 AAZ37343.1 - 0.0027 17.2 0.1 0.0057 16.1 0.1 1.5 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein K HHH_6 PF14579.6 AAZ37343.1 - 0.016 15.4 0.0 0.045 14.0 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif PCB_OB PF17092.5 AAZ37343.1 - 0.079 13.7 0.0 0.26 12.1 0.0 1.9 1 0 0 1 1 1 0 Penicillin-binding protein OB-like domain Peripla_BP_4 PF13407.6 AAZ37344.1 - 1.6e-58 198.3 10.2 1.8e-58 198.1 10.2 1.0 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 AAZ37344.1 - 2.7e-21 76.2 2.6 3.3e-21 75.9 2.6 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_3 PF13377.6 AAZ37344.1 - 1.8e-10 41.4 0.5 9.6e-10 39.0 0.1 2.1 1 1 1 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_6 PF13458.6 AAZ37344.1 - 7.8e-09 35.6 4.2 1.1e-08 35.1 4.2 1.2 1 0 0 1 1 1 1 Periplasmic binding protein IMP2_C PF18591.1 AAZ37344.1 - 0.028 14.3 0.1 0.098 12.5 0.1 1.9 1 0 0 1 1 1 0 Immune Mapped Protein 2 (IMP2) C-terminal domain MotB_plug PF13677.6 AAZ37345.1 - 6.7e-22 76.8 0.0 1.6e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 Membrane MotB of proton-channel complex MotA/MotB OmpA PF00691.20 AAZ37345.1 - 7.6e-15 55.1 0.0 1.7e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 OmpA family ABC_tran PF00005.27 AAZ37346.1 - 2.2e-38 131.8 0.0 2.9e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAZ37346.1 - 1.2e-08 35.1 0.0 0.0007 19.5 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAZ37346.1 - 1.9e-05 24.2 0.0 0.00094 18.7 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AAZ37346.1 - 9.1e-05 22.8 0.0 0.00016 22.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAZ37346.1 - 0.00071 20.0 0.0 0.0012 19.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 AAZ37346.1 - 0.00074 19.5 0.1 0.002 18.1 0.1 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_29 PF13555.6 AAZ37346.1 - 0.00083 19.1 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AAZ37346.1 - 0.0025 17.7 0.0 0.0046 16.9 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase T2SSE PF00437.20 AAZ37346.1 - 0.0029 16.7 0.0 0.0057 15.8 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_18 PF13238.6 AAZ37346.1 - 0.0038 17.8 0.0 0.0067 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AAZ37346.1 - 0.0063 16.3 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 AAZ37346.1 - 0.009 15.8 0.0 0.46 10.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain G-alpha PF00503.20 AAZ37346.1 - 0.011 15.0 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_33 PF13671.6 AAZ37346.1 - 0.012 15.7 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 AAZ37346.1 - 0.012 16.0 0.0 0.29 11.5 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 AAZ37346.1 - 0.015 14.8 0.0 0.026 14.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 AAZ37346.1 - 0.019 15.5 0.0 0.032 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 AAZ37346.1 - 0.019 15.2 0.1 0.053 13.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 AAZ37346.1 - 0.033 14.4 0.2 0.37 11.1 0.2 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF815 PF05673.13 AAZ37346.1 - 0.038 13.1 0.0 0.058 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 AAZ37346.1 - 0.043 13.1 0.0 0.088 12.1 0.0 1.5 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.6 AAZ37346.1 - 0.044 13.5 0.0 0.084 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 AAZ37346.1 - 0.051 12.9 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI APS_kinase PF01583.20 AAZ37346.1 - 0.084 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase RNA_helicase PF00910.22 AAZ37346.1 - 0.094 13.1 0.0 0.32 11.4 0.0 1.9 2 0 0 2 2 2 0 RNA helicase cobW PF02492.19 AAZ37346.1 - 0.097 12.2 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Herpes_Helicase PF02689.14 AAZ37346.1 - 0.13 10.1 0.0 0.18 9.7 0.0 1.2 1 0 0 1 1 1 0 Helicase AMP-binding PF00501.28 AAZ37347.1 - 3.2e-81 273.1 0.0 3.7e-81 272.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAZ37347.1 - 1.5e-08 35.5 0.0 4.4e-08 34.0 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PRA-CH PF01502.18 AAZ37348.1 - 8.8e-34 115.2 0.1 1.2e-33 114.8 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase SRF-TF PF00319.18 AAZ37348.1 - 0.16 11.5 0.1 0.47 10.0 0.0 1.7 1 1 1 2 2 2 0 SRF-type transcription factor (DNA-binding and dimerisation domain) RibD_C PF01872.17 AAZ37349.1 - 7.9e-43 146.6 0.0 9.2e-43 146.4 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain CinA PF02464.17 AAZ37351.1 - 4e-54 182.4 0.9 5.8e-54 181.9 0.9 1.2 1 0 0 1 1 1 1 Competence-damaged protein Rhodanese PF00581.20 AAZ37352.1 - 3.7e-16 59.6 0.0 4.9e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain BPD_transp_1 PF00528.22 AAZ37353.1 - 3.2e-22 79.2 10.7 4.7e-22 78.6 10.7 1.2 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component Holin_9 PF16936.5 AAZ37353.1 - 0.0029 17.7 1.3 0.0077 16.4 0.8 2.0 1 1 0 1 1 1 1 Putative holin TerD PF02342.18 AAZ37354.1 - 2.1e-32 112.1 0.0 2e-26 92.6 0.0 2.4 2 0 0 2 2 2 2 TerD domain DUF5525 PF17663.1 AAZ37354.1 - 0.062 11.4 11.0 0.087 10.9 11.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5525) DEC-1_N PF04625.13 AAZ37354.1 - 2.8 6.9 13.6 4.3 6.2 13.6 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DcrB PF08786.11 AAZ37355.1 - 0.006 16.7 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 DcrB DIM PF08194.12 AAZ37356.1 - 0.2 11.9 0.0 0.44 10.8 0.0 1.6 1 0 0 1 1 1 0 DIM protein VRP1 PF03538.14 AAZ37357.1 - 1.8e-34 119.6 0.0 2.4e-34 119.2 0.0 1.1 1 0 0 1 1 1 1 Salmonella virulence plasmid 28.1kDa A protein Lactamase_B PF00753.27 AAZ37358.1 - 4.9e-14 52.8 0.1 6.3e-14 52.5 0.1 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Sulfotransfer_3 PF13469.6 AAZ37358.1 - 0.014 15.8 0.0 0.022 15.1 0.0 1.3 1 0 0 1 1 1 0 Sulfotransferase family RHS_repeat PF05593.14 AAZ37359.1 - 2.1e-12 47.3 16.1 0.077 13.5 0.0 8.2 5 2 3 8 8 8 6 RHS Repeat TTc_toxin_rep PF18807.1 AAZ37359.1 - 0.047 13.5 0.1 0.17 11.8 0.1 2.1 1 0 0 1 1 1 0 Tripartite Tc toxins repeat Transposase_20 PF02371.16 AAZ37360.1 - 9.8e-25 86.7 0.8 2.2e-24 85.6 0.4 1.9 1 1 0 1 1 1 1 Transposase IS116/IS110/IS902 family DEDD_Tnp_IS110 PF01548.17 AAZ37360.1 - 1e-18 67.7 0.0 2.1e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 Transposase TetR_N PF00440.23 AAZ37360.1 - 0.19 11.5 3.0 5.7 6.8 0.0 3.5 4 0 0 4 4 4 0 Bacterial regulatory proteins, tetR family NIR_SIR_ferr PF03460.17 AAZ37361.1 - 7.5e-27 93.0 0.3 4e-15 55.4 0.0 2.4 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain NIR_SIR PF01077.22 AAZ37361.1 - 1.6e-12 47.2 0.0 1.3e-11 44.2 0.0 2.2 2 0 0 2 2 2 1 Nitrite and sulphite reductase 4Fe-4S domain RHH_4 PF13467.6 AAZ37362.1 - 2.6e-18 65.6 0.0 3.6e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Ribbon-helix-helix domain Pyr_redox_2 PF07992.14 AAZ37363.1 - 1.2e-60 205.2 0.4 1.4e-60 205.0 0.4 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAZ37363.1 - 1.1e-17 64.4 4.0 1.1e-12 48.3 0.6 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 AAZ37363.1 - 0.00026 21.0 3.7 0.37 10.8 0.1 2.9 2 2 0 2 2 2 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 AAZ37363.1 - 0.00033 19.8 2.6 0.2 10.7 0.0 2.7 3 0 0 3 3 3 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 AAZ37363.1 - 0.00052 20.2 4.8 0.47 10.7 0.2 2.9 2 1 0 2 2 2 2 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AAZ37363.1 - 0.001 18.8 12.1 1.1 8.8 0.6 3.4 4 0 0 4 4 4 3 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 AAZ37363.1 - 0.0022 17.3 0.5 0.25 10.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 AAZ37363.1 - 0.0064 16.7 0.7 0.6 10.4 0.1 2.5 2 0 0 2 2 2 1 TrkA-N domain ApbA PF02558.16 AAZ37363.1 - 0.0083 15.8 1.2 0.19 11.4 0.1 2.4 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 AAZ37363.1 - 0.0096 15.2 1.9 0.84 8.8 0.1 2.5 2 0 0 2 2 2 2 FAD binding domain K_oxygenase PF13434.6 AAZ37363.1 - 0.013 14.7 1.6 0.4 9.8 0.2 2.3 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.19 AAZ37363.1 - 0.021 14.2 0.1 0.077 12.4 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.21 AAZ37363.1 - 0.049 13.0 5.9 0.56 9.5 0.5 2.8 2 1 0 2 2 2 0 ThiF family Thi4 PF01946.17 AAZ37363.1 - 0.29 10.4 1.2 13 5.0 0.2 2.3 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 AAZ37363.1 - 0.3 9.7 4.9 1.7 7.3 0.1 2.8 3 0 0 3 3 3 0 HI0933-like protein Trp_halogenase PF04820.14 AAZ37363.1 - 0.91 8.3 4.3 0.55 9.0 0.8 2.2 3 0 0 3 3 3 0 Tryptophan halogenase GIDA PF01134.22 AAZ37363.1 - 3.9 6.5 7.6 38 3.2 0.0 3.2 3 1 0 3 3 3 0 Glucose inhibited division protein A ABC2_membrane PF01061.24 AAZ37364.1 - 0.0051 16.3 0.2 0.0051 16.3 0.2 1.7 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 AAZ37364.1 - 0.37 9.8 2.6 0.45 9.6 2.6 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein ABC_tran PF00005.27 AAZ37366.1 - 4.7e-33 114.6 0.0 8e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 AAZ37366.1 - 2.3e-25 89.8 3.0 3.3e-25 89.3 3.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 AAZ37366.1 - 1.3e-06 28.1 0.1 0.0028 17.1 0.0 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AAZ37366.1 - 1.8e-06 28.3 0.0 1e-05 25.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AAZ37366.1 - 6.2e-06 26.7 2.7 6.8e-06 26.6 1.1 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 AAZ37366.1 - 0.00033 20.6 0.1 0.00099 19.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AAZ37366.1 - 0.0005 19.8 0.1 0.0015 18.2 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 AAZ37366.1 - 0.0019 18.0 0.1 0.0052 16.5 0.1 1.7 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AAZ37366.1 - 0.0021 18.0 0.0 0.004 17.1 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA PF00004.29 AAZ37366.1 - 0.0026 18.2 0.0 0.046 14.2 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 AAZ37366.1 - 0.0056 16.8 0.5 0.076 13.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 AAZ37366.1 - 0.0086 16.1 0.2 0.028 14.4 0.0 1.9 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 AAZ37366.1 - 0.014 15.9 0.0 0.031 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_PrkA PF08298.11 AAZ37366.1 - 0.022 13.7 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain Zeta_toxin PF06414.12 AAZ37366.1 - 0.036 13.4 0.0 0.066 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 AAZ37366.1 - 0.049 13.2 0.6 0.15 11.6 0.3 1.9 1 1 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 AAZ37366.1 - 0.054 12.3 0.1 0.38 9.5 0.0 1.9 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Mg_chelatase PF01078.21 AAZ37366.1 - 0.065 12.6 0.1 0.25 10.7 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 AAZ37366.1 - 0.078 13.5 0.0 0.13 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 AAZ37366.1 - 0.084 12.8 0.1 0.63 9.9 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 AAZ37366.1 - 0.1 12.3 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 AAZ37366.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain Cytidylate_kin PF02224.18 AAZ37366.1 - 0.12 12.1 0.1 0.22 11.2 0.1 1.4 1 0 0 1 1 1 0 Cytidylate kinase AAA_15 PF13175.6 AAZ37366.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain APS_kinase PF01583.20 AAZ37366.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase ATP-synt_ab PF00006.25 AAZ37366.1 - 0.18 11.4 0.3 0.44 10.2 0.3 1.6 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain KduI PF04962.12 AAZ37367.1 - 1.3e-97 326.2 0.0 1.4e-97 326.1 0.0 1.0 1 0 0 1 1 1 1 KduI/IolB family polyprenyl_synt PF00348.17 AAZ37368.1 - 4.2e-56 189.9 0.3 5.2e-56 189.6 0.3 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase HEPN PF05168.14 AAZ37369.1 - 0.036 14.2 0.0 0.086 13.0 0.0 1.6 1 0 0 1 1 1 0 HEPN domain Lyase_aromatic PF00221.19 AAZ37370.1 - 4.5e-183 609.2 9.2 5.1e-183 609.0 9.2 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase TatD_DNase PF01026.21 AAZ37371.1 - 5.7e-61 206.1 0.0 6.6e-61 205.9 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 AAZ37371.1 - 0.02 14.7 0.4 0.046 13.5 0.4 1.6 1 1 0 1 1 1 0 Amidohydrolase MUG113 PF13455.6 AAZ37371.1 - 0.068 13.9 0.1 1.3 9.7 0.0 2.5 2 0 0 2 2 2 0 Meiotically up-regulated gene 113 Sulfatase PF00884.23 AAZ37372.1 - 3.3e-36 125.2 0.0 4.2e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 AAZ37372.1 - 0.032 13.8 0.2 0.19 11.3 0.0 2.1 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF3294 PF07957.11 AAZ37372.1 - 0.06 13.1 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) RseA_C PF03873.13 AAZ37373.1 - 1.1e-13 51.2 2.5 2.4e-13 50.1 2.5 1.6 1 0 0 1 1 1 1 Anti sigma-E protein RseA, C-terminal domain RseA_N PF03872.13 AAZ37373.1 - 1.4e-11 44.7 1.2 1.5e-11 44.6 0.3 1.4 2 0 0 2 2 2 1 Anti sigma-E protein RseA, N-terminal domain zf-HC2 PF13490.6 AAZ37373.1 - 0.4 11.0 1.8 1.7 9.0 0.9 2.4 2 0 0 2 2 2 0 Putative zinc-finger DUF4096 PF13340.6 AAZ37374.1 - 5.8e-25 87.3 0.4 1.5e-24 86.0 0.4 1.8 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1 PF01609.21 AAZ37374.1 - 3.2e-14 53.1 0.0 5.7e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AAZ37374.1 - 7.2e-10 39.1 0.2 2.1e-09 37.6 0.2 1.9 1 0 0 1 1 1 1 Transposase DDE domain HTH_Tnp_Tc3_2 PF01498.18 AAZ37374.1 - 0.061 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Transposase Pribosyltran PF00156.27 AAZ37375.1 - 4.9e-07 29.4 0.2 7.3e-07 28.8 0.2 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 AAZ37375.1 - 0.0021 17.6 0.0 0.0034 16.9 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase RraA-like PF03737.15 AAZ37376.1 - 2.2e-34 118.8 2.7 2.9e-34 118.4 2.7 1.1 1 0 0 1 1 1 1 Aldolase/RraA Thr_dehydrat_C PF00585.18 AAZ37377.1 - 1.5e-47 159.2 0.0 2.4e-26 91.3 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase PALP PF00291.25 AAZ37377.1 - 3e-13 49.8 1.0 4.1e-13 49.4 1.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF4761 PF15958.5 AAZ37377.1 - 0.022 14.9 0.0 0.059 13.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4761) Phage_base_V PF04717.12 AAZ37377.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Type VI secretion system, phage-baseplate injector Oxidored_q6 PF01058.22 AAZ37379.1 - 1.5e-21 76.6 0.1 2.2e-21 76.1 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit GFO_IDH_MocA PF01408.22 AAZ37380.1 - 9.5e-19 68.4 0.0 1.4e-18 67.9 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 AAZ37380.1 - 1.8e-10 40.8 0.0 3e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 AAZ37380.1 - 9.8e-05 23.0 0.2 0.00016 22.3 0.2 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF1748 PF08520.10 AAZ37380.1 - 0.11 12.4 0.1 0.25 11.3 0.1 1.6 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1748) DUF1611_N PF17396.2 AAZ37380.1 - 0.14 12.4 0.2 0.41 10.9 0.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1611_N) Rossmann-like domain tRNA-synt_1c PF00749.21 AAZ37381.1 - 1.1e-110 369.5 0.0 1.4e-110 369.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Pep_deformylase PF01327.21 AAZ37382.1 - 1.5e-44 151.4 0.0 1.7e-44 151.3 0.0 1.0 1 0 0 1 1 1 1 Polypeptide deformylase TatD_DNase PF01026.21 AAZ37383.1 - 4.6e-77 258.8 0.0 5.3e-77 258.6 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase CPSase_L_D2 PF02786.17 AAZ37384.1 - 4.4e-74 248.5 0.0 7e-74 247.9 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 AAZ37384.1 - 2.4e-41 140.7 0.9 6.1e-41 139.4 0.1 2.1 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 AAZ37384.1 - 1.9e-39 134.1 0.0 6.6e-39 132.4 0.0 1.9 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 AAZ37384.1 - 1.7e-11 43.8 0.4 4.4e-11 42.5 0.4 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp PF02222.22 AAZ37384.1 - 1.2e-09 38.0 0.0 7.3e-09 35.4 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 AAZ37384.1 - 3.6e-06 26.7 0.0 1.7e-05 24.6 0.0 2.2 1 0 0 1 1 1 1 Biotin-lipoyl like RnfC_N PF13375.6 AAZ37384.1 - 0.00029 20.8 0.1 0.0011 18.9 0.0 1.9 2 0 0 2 2 2 1 RnfC Barrel sandwich hybrid domain Dala_Dala_lig_C PF07478.13 AAZ37384.1 - 0.00045 19.8 0.0 0.001 18.7 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus Peptidase_M23 PF01551.22 AAZ37384.1 - 0.0019 18.4 0.1 0.58 10.4 0.0 3.0 2 1 1 3 3 3 2 Peptidase family M23 LAL_C2 PF18603.1 AAZ37384.1 - 0.0027 17.8 1.5 0.016 15.3 0.1 2.8 3 0 0 3 3 2 1 L-amino acid ligase C-terminal domain 2 ATPgrasp_ST PF14397.6 AAZ37384.1 - 0.02 14.1 0.0 0.066 12.4 0.0 1.7 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp GCV_H PF01597.19 AAZ37384.1 - 0.042 13.7 0.1 0.092 12.6 0.1 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein ATP-grasp_3 PF02655.14 AAZ37384.1 - 0.089 12.8 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain Ribosomal_S5_C PF03719.15 AAZ37385.1 - 3.6e-31 106.4 0.4 5.6e-31 105.8 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 AAZ37385.1 - 9.3e-28 96.0 2.9 9.3e-28 96.0 2.9 1.7 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain GTP_EFTU PF00009.27 AAZ37386.1 - 7e-56 188.8 0.0 8.9e-56 188.5 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 AAZ37386.1 - 1.6e-34 118.6 0.1 3.7e-34 117.4 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 AAZ37386.1 - 2.5e-15 56.6 4.0 2.5e-15 56.6 4.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 AAZ37386.1 - 6.7e-05 22.9 0.0 0.00014 21.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 AAZ37386.1 - 0.026 14.4 0.0 0.1 12.5 0.0 1.9 1 1 1 2 2 2 0 RsgA GTPase cobW PF02492.19 AAZ37386.1 - 0.13 11.9 0.1 0.32 10.6 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Yop-YscD_cpl PF16697.5 AAZ37387.1 - 5.7e-13 49.0 0.3 1.1e-12 48.0 0.3 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Yop-YscD_ppl PF16693.5 AAZ37387.1 - 3.6e-10 39.7 0.0 5.1e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Inner membrane component of T3SS, periplasmic domain FHA PF00498.26 AAZ37387.1 - 0.011 16.0 0.0 0.027 14.8 0.0 1.6 1 0 0 1 1 1 0 FHA domain Peripla_BP_4 PF13407.6 AAZ37388.1 - 1.2e-13 51.2 0.0 2.4e-13 50.3 0.0 1.5 1 1 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 AAZ37388.1 - 3.6e-10 39.7 0.0 4.3e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_3 PF13377.6 AAZ37388.1 - 9.2e-06 26.1 0.0 2.4e-05 24.7 0.0 1.7 1 1 1 2 2 2 1 Periplasmic binding protein-like domain MmgE_PrpD PF03972.14 AAZ37388.1 - 0.012 14.2 0.0 0.017 13.7 0.0 1.2 1 0 0 1 1 1 0 MmgE/PrpD family Response_reg PF00072.24 AAZ37389.1 - 2.1e-30 105.2 0.0 4.8e-30 104.0 0.0 1.6 2 0 0 2 2 2 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAZ37389.1 - 5e-17 61.8 0.0 1.1e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal MarR PF01047.22 AAZ37390.1 - 3.7e-15 55.6 0.1 3.7e-15 55.6 0.1 1.7 2 0 0 2 2 2 1 MarR family MarR_2 PF12802.7 AAZ37390.1 - 2e-12 46.8 0.1 3.8e-12 45.9 0.1 1.5 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 AAZ37390.1 - 4.2e-11 43.2 0.1 6.9e-11 42.5 0.1 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_24 PF13412.6 AAZ37390.1 - 0.00035 20.1 0.1 0.001 18.6 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HxlR PF01638.17 AAZ37390.1 - 0.0011 18.8 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 HxlR-like helix-turn-helix FeoC PF09012.10 AAZ37390.1 - 0.0018 18.3 0.0 0.0031 17.5 0.0 1.4 1 0 0 1 1 1 1 FeoC like transcriptional regulator B-block_TFIIIC PF04182.12 AAZ37390.1 - 0.0019 18.3 0.0 0.0039 17.3 0.0 1.7 1 1 0 1 1 1 1 B-block binding subunit of TFIIIC PadR PF03551.14 AAZ37390.1 - 0.0031 17.5 0.0 0.0047 16.9 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family Replic_Relax PF13814.6 AAZ37390.1 - 0.0032 17.6 0.1 0.0036 17.4 0.1 1.1 1 0 0 1 1 1 1 Replication-relaxation HTH_34 PF13601.6 AAZ37390.1 - 0.0037 17.4 0.0 0.0067 16.6 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_IclR PF09339.10 AAZ37390.1 - 0.0045 16.8 0.8 0.016 15.0 0.0 2.2 3 0 0 3 3 3 1 IclR helix-turn-helix domain TrmB PF01978.19 AAZ37390.1 - 0.009 15.9 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB DUF4129 PF13559.6 AAZ37390.1 - 0.037 14.3 0.4 0.21 11.8 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4129) HTH_45 PF14947.6 AAZ37390.1 - 0.038 14.0 0.0 0.076 13.0 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DUF2250 PF10007.9 AAZ37390.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) Fe_dep_repress PF01325.19 AAZ37390.1 - 0.11 12.6 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Crp PF00325.20 AAZ37390.1 - 0.26 11.0 2.4 2.8 7.7 0.2 2.6 2 0 0 2 2 2 0 Bacterial regulatory proteins, crp family Citrate_synt PF00285.21 AAZ37392.1 - 1.8e-118 395.7 0.0 2.1e-118 395.5 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Acyl_transf_3 PF01757.22 AAZ37393.1 - 1.2e-28 100.2 42.7 1.3e-28 100.1 42.7 1.0 1 0 0 1 1 1 1 Acyltransferase family HTH_3 PF01381.22 AAZ37394.1 - 6.6e-11 42.1 0.0 1.1e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 AAZ37394.1 - 3e-09 36.8 0.0 4.5e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 AAZ37394.1 - 2.8e-08 34.0 0.0 6.1e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 AAZ37394.1 - 0.025 15.0 0.0 0.035 14.5 0.0 1.2 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain CaMKII_AD PF08332.10 AAZ37395.1 - 5.6e-29 100.9 0.0 6.7e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain DUF4440 PF14534.6 AAZ37395.1 - 3.5e-13 49.9 0.0 5.4e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 AAZ37395.1 - 1.8e-10 41.1 0.0 2.3e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 AAZ37395.1 - 3.9e-07 30.7 0.0 5.5e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.6 AAZ37395.1 - 3.8e-05 23.8 0.1 0.00018 21.7 0.1 1.8 1 1 0 1 1 1 1 SnoaL-like domain DUF3225 PF11533.8 AAZ37395.1 - 0.017 14.8 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3225) He_PIG PF05345.12 AAZ37395.1 - 0.041 14.1 0.0 0.089 13.0 0.0 1.6 1 0 0 1 1 1 0 Putative Ig domain Invasin_D3 PF09134.10 AAZ37395.1 - 0.17 12.2 1.6 1.3 9.4 1.6 2.1 1 1 0 1 1 1 0 Invasin, domain 3 PhyH PF05721.13 AAZ37396.1 - 8.7e-27 94.7 0.1 1.1e-26 94.5 0.1 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) TauD PF02668.16 AAZ37396.1 - 0.075 12.8 1.1 0.44 10.3 0.1 2.3 2 1 0 2 2 2 0 Taurine catabolism dioxygenase TauD, TfdA family TauE PF01925.19 AAZ37397.1 - 4.8e-41 140.9 29.1 5.9e-41 140.7 29.1 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE Gly-zipper_Omp PF13488.6 AAZ37397.1 - 6.8e-05 22.8 0.1 6.8e-05 22.8 0.1 3.6 4 0 0 4 4 4 1 Glycine zipper Gly-zipper_OmpA PF13436.6 AAZ37397.1 - 0.015 15.1 4.9 0.015 15.1 4.9 3.2 3 0 0 3 3 3 0 Glycine-zipper domain DUF3482 PF11981.8 AAZ37397.1 - 0.36 10.2 2.9 5.2 6.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3482) Rieske_2 PF13806.6 AAZ37398.1 - 7.3e-36 122.3 0.0 8.6e-36 122.0 0.0 1.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain UPF0227 PF05728.12 AAZ37399.1 - 5.5e-59 199.3 0.1 6.2e-59 199.1 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_6 PF12697.7 AAZ37399.1 - 2.4e-05 25.0 0.3 3.3e-05 24.6 0.3 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAZ37399.1 - 0.0085 15.4 0.1 0.019 14.3 0.1 1.6 1 1 1 2 2 2 1 Serine aminopeptidase, S33 GcnA_N PF18229.1 AAZ37399.1 - 0.13 12.4 0.0 0.64 10.1 0.0 2.1 1 1 1 2 2 2 0 N-acetyl-beta-D-glucosaminidase N-terminal domain DUF2713 PF10897.8 AAZ37399.1 - 0.19 11.3 0.0 0.3 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2713) Transposase_mut PF00872.18 AAZ37400.1 - 9.5e-21 74.1 0.0 1.1e-20 73.9 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family THDPS_M PF14789.6 AAZ37401.1 - 1.3e-16 60.4 0.0 2.7e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 Tetrahydrodipicolinate N-succinyltransferase middle Hexapep_2 PF14602.6 AAZ37401.1 - 1.9e-11 43.5 3.0 1.9e-11 43.5 3.0 2.6 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase THDPS_N PF14790.6 AAZ37401.1 - 3.1e-05 23.8 0.0 4.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrodipicolinate N-succinyltransferase N-terminal Hexapep PF00132.24 AAZ37401.1 - 0.0075 16.0 6.7 0.14 12.0 0.8 3.7 3 1 0 3 3 3 1 Bacterial transferase hexapeptide (six repeats) MBOAT PF03062.19 AAZ37402.1 - 2e-27 96.5 10.7 2e-27 96.5 10.7 2.3 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 AAZ37402.1 - 0.0036 17.5 4.2 0.0099 16.1 4.2 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Abhydrolase_2 PF02230.16 AAZ37403.1 - 3.7e-41 141.3 0.0 4.4e-41 141.1 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 AAZ37403.1 - 3.3e-07 29.8 0.2 0.0022 17.3 0.0 2.5 2 1 1 3 3 3 2 Serine aminopeptidase, S33 FSH1 PF03959.13 AAZ37403.1 - 1.4e-06 28.1 0.1 6.8e-06 25.9 0.1 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 AAZ37403.1 - 7.7e-06 26.7 0.4 9.1e-06 26.4 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 AAZ37403.1 - 7.5e-05 22.7 0.1 0.0021 18.0 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 AAZ37403.1 - 0.00014 21.5 0.0 0.0002 21.0 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 AAZ37403.1 - 0.00015 21.3 0.1 0.099 12.1 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.20 AAZ37403.1 - 0.00078 19.2 0.5 0.0027 17.4 0.5 1.8 1 1 0 1 1 1 1 Putative esterase Esterase_phd PF10503.9 AAZ37403.1 - 0.047 13.2 0.0 0.95 8.9 0.0 2.2 2 1 0 2 2 2 0 Esterase PHB depolymerase Abhydrolase_1 PF00561.20 AAZ37403.1 - 0.063 12.9 0.1 2.3 7.8 0.0 2.2 1 1 1 2 2 2 0 alpha/beta hydrolase fold AXE1 PF05448.12 AAZ37403.1 - 0.074 11.7 0.0 0.091 11.4 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) RuvX PF03652.15 AAZ37404.1 - 1.5e-41 141.9 0.0 1.7e-41 141.7 0.0 1.0 1 0 0 1 1 1 1 Holliday junction resolvase GFO_IDH_MocA PF01408.22 AAZ37404.1 - 0.13 13.1 0.0 0.37 11.6 0.0 1.7 1 1 1 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold AidB_N PF18158.1 AAZ37405.1 - 1.7e-60 203.4 0.2 3.9e-60 202.3 0.0 1.7 2 0 0 2 2 2 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_1 PF00441.24 AAZ37405.1 - 2.8e-27 95.8 0.4 4.8e-27 95.0 0.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 AAZ37405.1 - 9.9e-14 51.3 0.0 2e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 AAZ37405.1 - 4.2e-10 40.0 0.5 8.6e-10 39.0 0.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain BPD_transp_1 PF00528.22 AAZ37406.1 - 2.9e-24 85.8 5.8 2.9e-24 85.8 5.8 1.7 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 AAZ37406.1 - 0.033 14.2 4.5 0.13 12.3 0.1 3.2 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C LptF_LptG PF03739.14 AAZ37407.1 - 9.2e-67 225.4 3.2 1e-66 225.2 3.2 1.0 1 0 0 1 1 1 1 Lipopolysaccharide export system permease LptF/LptG DUF4131 PF13567.6 AAZ37407.1 - 3.8 7.1 0.0 3.8 7.1 0.0 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) Ribosomal_L27 PF01016.19 AAZ37409.1 - 1.5e-36 124.2 3.7 1.7e-36 124.1 3.7 1.0 1 0 0 1 1 1 1 Ribosomal L27 protein N_methyl PF07963.12 AAZ37410.1 - 1.1e-07 31.1 1.6 1.7e-07 30.5 1.6 1.3 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif T2SSJ PF11612.8 AAZ37410.1 - 7.6e-05 23.0 0.1 0.0001 22.5 0.1 1.3 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein J Sigma54_activat PF00158.26 AAZ37411.1 - 4.1e-67 225.1 0.0 5.5e-67 224.7 0.0 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AAZ37411.1 - 3.1e-20 72.7 0.0 5.9e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 AAZ37411.1 - 6.1e-06 26.3 0.0 1.1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) GAF PF01590.26 AAZ37411.1 - 1.8e-05 25.4 0.1 3.8e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 GAF domain Mg_chelatase PF01078.21 AAZ37411.1 - 2e-05 24.1 0.2 0.0021 17.5 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA PF00004.29 AAZ37411.1 - 4.9e-05 23.8 0.0 0.0001 22.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 AAZ37411.1 - 0.0019 18.3 0.0 0.0033 17.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) HTH_8 PF02954.19 AAZ37411.1 - 0.0026 17.5 0.2 0.014 15.1 0.1 2.3 1 1 1 2 2 2 1 Bacterial regulatory protein, Fis family GAF_2 PF13185.6 AAZ37411.1 - 0.019 15.2 0.1 0.057 13.7 0.0 1.9 2 0 0 2 2 2 0 GAF domain Peptidase_M24 PF00557.24 AAZ37413.1 - 4.5e-58 196.4 0.1 5.1e-58 196.2 0.1 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF4926 PF16277.5 AAZ37413.1 - 0.073 12.4 0.0 0.2 11.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4926) FUSC PF04632.12 AAZ37414.1 - 6.9e-219 728.7 38.6 7.8e-219 728.5 38.6 1.0 1 0 0 1 1 1 1 Fusaric acid resistance protein family FUSC_2 PF13515.6 AAZ37414.1 - 2.1e-14 53.7 31.2 6.3e-13 48.9 12.8 2.9 2 1 0 2 2 2 2 Fusaric acid resistance protein-like ArAE_1 PF06081.11 AAZ37414.1 - 4.8e-05 23.5 4.6 4.8e-05 23.5 4.6 3.1 2 2 0 2 2 2 1 Aromatic acid exporter family member 1 ALMT PF11744.8 AAZ37414.1 - 0.0019 17.1 5.3 0.0032 16.4 5.3 1.3 1 0 0 1 1 1 1 Aluminium activated malate transporter Zn_protease PF05618.11 AAZ37415.1 - 7.4e-45 152.2 0.0 8.4e-45 152.0 0.0 1.0 1 0 0 1 1 1 1 Putative ATP-dependant zinc protease gag-asp_proteas PF13975.6 AAZ37415.1 - 0.089 13.4 0.0 0.61 10.7 0.0 2.0 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF4096 PF13340.6 AAZ37416.1 - 5.9e-25 87.3 0.4 1.5e-24 86.0 0.4 1.7 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1 PF01609.21 AAZ37416.1 - 5.5e-14 52.3 0.0 9.7e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AAZ37416.1 - 2.4e-08 34.2 0.1 7.4e-08 32.7 0.1 1.9 1 0 0 1 1 1 1 Transposase DDE domain HTH_Tnp_Tc3_2 PF01498.18 AAZ37416.1 - 0.063 13.5 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Transposase PseudoU_synth_2 PF00849.22 AAZ37417.1 - 2.1e-23 83.1 0.0 2.9e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase SUKH_6 PF14568.6 AAZ37418.1 - 3.7e-14 53.2 0.2 6.7e-14 52.4 0.2 1.4 1 0 0 1 1 1 1 SMI1-KNR4 cell-wall SUKH_5 PF14567.6 AAZ37418.1 - 1.6e-10 40.8 0.0 2.5e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 SMI1-KNR4 cell-wall SMI1_KNR4 PF09346.10 AAZ37418.1 - 1.9e-09 38.0 0.4 4.3e-09 36.9 0.0 1.7 2 1 1 3 3 3 1 SMI1 / KNR4 family (SUKH-1) Fer2_4 PF13510.6 AAZ37419.1 - 1.2e-19 70.1 0.0 1.4e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain ABC_tran PF00005.27 AAZ37420.1 - 1.9e-32 112.7 0.0 2.5e-32 112.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAZ37420.1 - 7.5e-06 26.0 0.0 0.007 16.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AAZ37420.1 - 1e-05 26.0 0.3 1.6e-05 25.3 0.3 1.4 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 AAZ37420.1 - 3.4e-05 23.4 0.0 0.067 12.6 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 AAZ37420.1 - 6.9e-05 22.5 0.5 0.004 16.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 AAZ37420.1 - 0.00011 22.5 0.1 0.00032 21.0 0.1 1.8 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AAZ37420.1 - 0.00056 19.8 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase ABC_ATPase PF09818.9 AAZ37420.1 - 0.00096 18.1 0.1 0.91 8.2 0.0 2.7 2 1 0 2 2 2 2 Predicted ATPase of the ABC class AAA_33 PF13671.6 AAZ37420.1 - 0.0011 19.2 0.0 0.0023 18.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 AAZ37420.1 - 0.0013 19.0 0.0 0.22 11.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 AAZ37420.1 - 0.0018 18.4 0.0 0.0033 17.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATPase PF06745.13 AAZ37420.1 - 0.0026 17.1 0.0 1.3 8.4 0.0 2.1 2 0 0 2 2 2 2 KaiC AAA_30 PF13604.6 AAZ37420.1 - 0.0053 16.5 0.1 0.017 14.9 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_29 PF13555.6 AAZ37420.1 - 0.0071 16.1 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain NB-ARC PF00931.22 AAZ37420.1 - 0.016 14.4 0.1 0.067 12.4 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain AAA_23 PF13476.6 AAZ37420.1 - 0.034 14.7 0.0 0.053 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 AAZ37420.1 - 0.043 13.7 0.3 0.095 12.6 0.1 1.7 2 0 0 2 2 2 0 NACHT domain Rad17 PF03215.15 AAZ37420.1 - 0.072 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_15 PF13175.6 AAZ37420.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 AAZ37420.1 - 0.22 11.2 0.1 0.8 9.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain START PF01852.19 AAZ37421.1 - 8.8e-05 22.0 0.0 9.9e-05 21.8 0.0 1.0 1 0 0 1 1 1 1 START domain DegT_DnrJ_EryC1 PF01041.17 AAZ37422.1 - 3.3e-103 345.8 0.0 3.9e-103 345.5 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 AAZ37422.1 - 3.2e-05 22.7 0.0 4.2e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 AAZ37422.1 - 0.0069 15.7 0.0 0.015 14.6 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 AAZ37422.1 - 0.02 13.9 0.0 0.18 10.7 0.0 1.9 2 0 0 2 2 2 0 Aminotransferase class-V DUF4411 PF14367.6 AAZ37423.1 - 1e-45 155.5 0.0 1.2e-45 155.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4411) Phage_sheath_1C PF17482.2 AAZ37424.1 - 1.2e-08 34.9 0.0 1.4e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 Phage tail sheath C-terminal domain 30K_MP_C_Ter PF11330.8 AAZ37424.1 - 0.17 11.1 0.0 0.23 10.8 0.0 1.1 1 0 0 1 1 1 0 C-Terminal of 30K viral movement proteins Flavodoxin_2 PF02525.17 AAZ37425.1 - 1.6e-45 155.3 0.0 1.8e-45 155.1 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 AAZ37425.1 - 2.5e-12 46.8 0.0 3.1e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Transposase_mut PF00872.18 AAZ37426.1 - 1.5e-117 392.7 0.0 1.9e-117 392.3 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ37426.1 - 7.7e-05 23.0 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain DUF4844 PF16133.5 AAZ37426.1 - 0.23 12.0 0.0 0.55 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) Radical_SAM PF04055.21 AAZ37427.1 - 8.4e-25 88.1 0.0 1.2e-24 87.5 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 AAZ37427.1 - 1.9e-08 34.6 0.0 3.5e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain SPASM PF13186.6 AAZ37427.1 - 3.2e-08 34.0 0.3 7.1e-08 32.8 0.3 1.6 1 0 0 1 1 1 1 Iron-sulfur cluster-binding domain Fer4_14 PF13394.6 AAZ37427.1 - 6.6e-07 29.5 0.0 6.6e-07 29.5 0.0 1.9 2 1 0 2 2 2 1 4Fe-4S single cluster domain AP_endonuc_2 PF01261.24 AAZ37427.1 - 0.0014 18.1 0.0 0.043 13.3 0.0 2.2 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel Spt4 PF06093.13 AAZ37427.1 - 0.46 10.6 3.2 5.1 7.3 0.5 2.6 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger SinI PF08671.10 AAZ37427.1 - 2.1 8.2 5.4 2.6 7.9 0.2 2.8 3 0 0 3 3 3 0 Anti-repressor SinI PNTB_4TM PF12769.7 AAZ37428.1 - 2.6e-35 120.7 8.9 3e-35 120.5 8.9 1.0 1 0 0 1 1 1 1 4TM region of pyridine nucleotide transhydrogenase, mitoch Adeno_E3_14_5 PF04834.12 AAZ37428.1 - 0.058 13.9 2.7 0.066 13.7 2.4 1.3 1 1 0 1 1 1 0 Early E3 14.5 kDa protein DUF3392 PF11872.8 AAZ37428.1 - 0.11 12.8 5.2 0.073 13.3 3.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3392) DUF3754 PF12576.8 AAZ37428.1 - 0.22 11.5 1.2 0.31 11.0 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3754) Acetyltransf_18 PF18014.1 AAZ37429.1 - 8.4e-19 67.6 0.0 2.1e-18 66.4 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAZ37429.1 - 1.1e-13 51.2 0.0 1.8e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAZ37429.1 - 1.7e-12 47.6 0.0 2.9e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAZ37429.1 - 2.5e-09 37.4 0.0 8e-09 35.8 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 AAZ37429.1 - 0.049 13.8 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 AAZ37429.1 - 0.12 12.5 0.0 0.76 9.9 0.0 2.3 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAZ37429.1 - 0.14 12.2 0.1 0.72 9.9 0.1 2.1 1 1 0 1 1 1 0 FR47-like protein GNAT_acetyltran PF12746.7 AAZ37429.1 - 0.21 11.1 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase Tn7_Tnp_TnsA_N PF08722.11 AAZ37430.1 - 0.00013 22.1 0.0 0.00019 21.6 0.0 1.3 1 0 0 1 1 1 1 TnsA endonuclease N terminal ABC_tran PF00005.27 AAZ37431.1 - 3.3e-28 98.9 0.0 4.5e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 AAZ37431.1 - 4.8e-18 65.4 0.3 8.5e-18 64.6 0.3 1.4 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region SMC_N PF02463.19 AAZ37431.1 - 2.6e-05 23.8 0.0 3.9e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AAZ37431.1 - 0.00077 19.8 0.0 0.0024 18.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 AAZ37431.1 - 0.0036 17.2 0.2 1.1 9.0 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Mg_chelatase PF01078.21 AAZ37431.1 - 0.012 15.0 0.0 0.036 13.4 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 AAZ37431.1 - 0.014 15.8 0.7 0.023 15.1 0.3 1.7 2 1 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 AAZ37431.1 - 0.053 13.4 0.0 0.082 12.8 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 AAZ37431.1 - 0.059 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 AAZ37431.1 - 0.066 12.8 0.0 0.18 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 AAZ37431.1 - 0.08 13.4 0.0 0.22 12.0 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 AAZ37431.1 - 0.19 11.0 0.1 0.8 9.0 0.0 1.8 2 0 0 2 2 2 0 KaiC PilN PF05137.13 AAZ37432.1 - 1.2e-19 70.2 0.1 1.8e-19 69.6 0.1 1.3 1 0 0 1 1 1 1 Fimbrial assembly protein (PilN) DUF4131 PF13567.6 AAZ37432.1 - 0.007 16.0 0.1 0.011 15.4 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) T2SSM PF04612.12 AAZ37432.1 - 0.045 13.8 1.0 0.052 13.6 0.1 1.5 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M NUFIP1 PF10453.9 AAZ37432.1 - 0.24 11.3 1.5 0.57 10.1 1.5 1.7 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Alpha-E PF04168.12 AAZ37433.1 - 3.1e-97 325.9 7.1 3.5e-97 325.7 7.1 1.0 1 0 0 1 1 1 1 A predicted alpha-helical domain with a conserved ER motif. TPR_9 PF13371.6 AAZ37433.1 - 0.064 13.4 3.6 0.13 12.4 1.6 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyco_transf_28 PF03033.20 AAZ37434.1 - 2.8e-43 147.3 0.1 5.6e-43 146.3 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_tran_28_C PF04101.16 AAZ37434.1 - 5.6e-38 130.5 0.0 7.7e-38 130.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_4_4 PF13579.6 AAZ37434.1 - 4.2e-07 30.5 3.9 4.8e-07 30.4 0.3 2.3 1 1 2 3 3 3 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 AAZ37434.1 - 0.00046 20.2 0.1 0.0014 18.7 0.1 1.8 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_2 PF13477.6 AAZ37434.1 - 0.0005 20.1 0.0 0.0012 18.8 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase 4-like Response_reg PF00072.24 AAZ37435.1 - 8.5e-27 93.5 0.0 2e-26 92.4 0.0 1.6 2 0 0 2 2 2 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAZ37435.1 - 8.2e-25 86.7 0.0 1.8e-24 85.6 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal UDPGT PF00201.18 AAZ37435.1 - 0.13 11.0 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase MFS_1 PF07690.16 AAZ37436.1 - 4.1e-39 134.5 62.4 2.5e-31 108.9 28.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AAZ37436.1 - 2.3e-16 59.7 28.2 1.1e-14 54.2 12.4 3.0 1 1 2 3 3 3 3 Sugar (and other) transporter MFS_4 PF06779.14 AAZ37436.1 - 2e-08 34.0 40.3 3e-08 33.3 40.3 1.4 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 AAZ37436.1 - 0.25 10.2 25.3 0.016 14.1 9.2 3.0 2 1 1 3 3 3 0 MFS_1 like family P5-ATPase PF12409.8 AAZ37436.1 - 0.36 10.9 1.0 0.98 9.5 1.0 1.7 1 0 0 1 1 1 0 P5-type ATPase cation transporter PTPS_related PF10131.9 AAZ37436.1 - 0.71 8.1 8.6 0.12 10.7 1.5 2.2 2 0 0 2 2 2 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein MFS_Mycoplasma PF07672.13 AAZ37436.1 - 1.4 8.2 8.2 0.051 12.9 1.2 2.2 2 1 0 2 2 2 0 Mycoplasma MFS transporter Ser_hydrolase PF06821.13 AAZ37437.1 - 2e-69 232.8 2.3 2.3e-69 232.6 2.3 1.0 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_6 PF12697.7 AAZ37437.1 - 3.9e-07 30.9 0.7 6e-07 30.3 0.7 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAZ37437.1 - 2e-06 27.2 0.1 8.8e-05 21.9 0.0 2.0 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AAZ37437.1 - 0.0016 18.2 0.2 0.76 9.4 0.0 2.5 2 1 1 3 3 3 2 alpha/beta hydrolase fold DEC-1_N PF04625.13 AAZ37437.1 - 0.011 14.8 0.5 0.014 14.5 0.5 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF1749 PF08538.10 AAZ37437.1 - 0.18 10.8 0.0 0.27 10.3 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1749) PKcGMP_CC PF16808.5 AAZ37438.1 - 0.00072 19.4 0.3 0.0019 18.0 0.1 1.8 2 0 0 2 2 2 1 Coiled-coil N-terminus of cGMP-dependent protein kinase Sigma54_activat PF00158.26 AAZ37439.1 - 5.6e-72 240.9 0.0 7.6e-72 240.5 0.0 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AAZ37439.1 - 3.7e-24 85.4 0.0 8e-24 84.3 0.0 1.6 1 1 0 1 1 1 1 Sigma-54 interaction domain Response_reg PF00072.24 AAZ37439.1 - 1.1e-21 77.1 0.1 6.8e-21 74.5 0.0 2.2 2 0 0 2 2 2 1 Response regulator receiver domain AAA_5 PF07728.14 AAZ37439.1 - 8.4e-09 35.5 0.1 7.9e-08 32.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA PF00004.29 AAZ37439.1 - 7e-05 23.3 0.0 0.00013 22.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 AAZ37439.1 - 8.5e-05 22.0 0.3 0.002 17.5 0.3 2.3 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 AAZ37439.1 - 0.00015 21.9 0.0 0.00033 20.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 AAZ37439.1 - 0.00082 19.8 0.2 0.0019 18.6 0.2 1.7 1 0 0 1 1 1 1 AAA ATPase domain HTH_11 PF08279.12 AAZ37439.1 - 0.011 15.6 0.0 0.058 13.3 0.0 2.2 2 0 0 2 2 2 0 HTH domain HTH_AsnC-type PF13404.6 AAZ37439.1 - 0.027 14.3 1.5 0.073 12.9 0.1 2.4 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_8 PF02954.19 AAZ37439.1 - 0.044 13.6 0.7 0.22 11.3 0.1 2.7 3 0 0 3 3 3 0 Bacterial regulatory protein, Fis family HTH_23 PF13384.6 AAZ37440.1 - 0.00062 19.5 0.0 0.0016 18.1 0.0 1.6 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r4_2 PF08281.12 AAZ37440.1 - 0.13 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 EAL PF00563.20 AAZ37441.1 - 4.6e-56 190.0 0.0 5.5e-56 189.8 0.0 1.0 1 0 0 1 1 1 1 EAL domain ARA70 PF12489.8 AAZ37442.1 - 0.2 11.8 2.3 0.16 12.1 0.3 1.8 2 0 0 2 2 2 0 Nuclear coactivator ABC_tran PF00005.27 AAZ37443.1 - 1e-54 184.8 0.0 1.3e-31 109.9 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 AAZ37443.1 - 4.1e-20 72.8 3.3 4.2e-07 30.1 0.1 4.2 2 2 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 AAZ37443.1 - 7.5e-13 48.9 1.7 1.1e-05 25.7 0.0 3.3 2 2 0 2 2 2 2 AAA domain SMC_N PF02463.19 AAZ37443.1 - 7.9e-11 41.8 0.1 9.7e-05 21.9 0.0 2.8 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AAZ37443.1 - 2.5e-09 37.8 3.6 3.9e-05 24.1 0.3 2.5 2 1 0 2 2 2 2 AAA ATPase domain TniB PF05621.11 AAZ37443.1 - 2.6e-07 30.2 0.2 0.61 9.5 0.0 4.4 4 0 0 4 4 4 1 Bacterial TniB protein AAA_33 PF13671.6 AAZ37443.1 - 1e-06 29.0 0.1 0.012 15.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 AAZ37443.1 - 1.4e-06 28.0 0.3 0.032 14.0 0.1 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AAZ37443.1 - 6.8e-06 26.1 1.6 0.085 12.8 0.1 2.6 3 0 0 3 3 2 2 RsgA GTPase AAA_23 PF13476.6 AAZ37443.1 - 2.3e-05 25.0 0.0 0.084 13.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 AAZ37443.1 - 9.6e-05 22.4 0.0 0.32 11.1 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_5 PF07728.14 AAZ37443.1 - 0.0002 21.4 3.1 1.7 8.7 0.1 3.7 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 AAZ37443.1 - 0.00053 19.8 0.0 1 9.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 AAZ37443.1 - 0.00079 19.6 0.4 0.26 11.3 0.1 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain G-alpha PF00503.20 AAZ37443.1 - 0.00082 18.6 0.0 0.25 10.5 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit AAA PF00004.29 AAZ37443.1 - 0.00088 19.7 0.2 0.39 11.1 0.0 3.4 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 AAZ37443.1 - 0.00094 18.7 0.4 1 8.8 0.1 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 AAZ37443.1 - 0.0014 19.1 0.1 1.3 9.6 0.0 2.8 3 0 0 3 3 2 1 AAA domain PRK PF00485.18 AAZ37443.1 - 0.0015 18.3 0.1 1.9 8.2 0.0 2.3 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family Pox_A32 PF04665.12 AAZ37443.1 - 0.0017 17.9 0.3 2 7.8 0.1 2.4 2 0 0 2 2 2 2 Poxvirus A32 protein AAA_30 PF13604.6 AAZ37443.1 - 0.0017 18.1 2.5 0.4 10.4 0.0 2.9 3 1 1 4 4 3 1 AAA domain Sigma54_activat PF00158.26 AAZ37443.1 - 0.0022 17.7 1.0 2.9 7.6 0.0 2.9 3 0 0 3 3 3 2 Sigma-54 interaction domain NACHT PF05729.12 AAZ37443.1 - 0.0025 17.7 0.4 1.2 9.0 0.1 2.7 2 0 0 2 2 2 1 NACHT domain ABC_ATPase PF09818.9 AAZ37443.1 - 0.0035 16.2 0.1 0.46 9.2 0.0 3.6 3 1 0 3 3 3 1 Predicted ATPase of the ABC class FtsK_SpoIIIE PF01580.18 AAZ37443.1 - 0.004 16.5 0.7 0.45 9.8 0.0 2.6 3 0 0 3 3 2 1 FtsK/SpoIIIE family TsaE PF02367.17 AAZ37443.1 - 0.0058 16.6 0.1 0.98 9.4 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 AAZ37443.1 - 0.0072 15.7 0.1 2.4 7.5 0.0 2.7 3 0 0 3 3 2 1 Magnesium chelatase, subunit ChlI Roc PF08477.13 AAZ37443.1 - 0.0087 16.3 0.1 6.6 7.0 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase oligo_HPY PF08352.12 AAZ37443.1 - 0.015 15.8 0.1 0.95 10.0 0.0 2.5 2 0 0 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region Septin PF00735.18 AAZ37443.1 - 0.016 14.5 0.0 5.5 6.2 0.0 2.3 2 0 0 2 2 2 0 Septin IstB_IS21 PF01695.17 AAZ37443.1 - 0.017 14.8 0.2 2.8 7.6 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein ATP-synt_ab PF00006.25 AAZ37443.1 - 0.022 14.4 0.0 1 9.0 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Dynamin_N PF00350.23 AAZ37443.1 - 0.023 14.8 0.0 3.8 7.6 0.0 2.3 2 0 0 2 2 2 0 Dynamin family NB-ARC PF00931.22 AAZ37443.1 - 0.03 13.5 0.1 8.2 5.5 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_19 PF13245.6 AAZ37443.1 - 0.043 14.1 0.1 3.6 7.9 0.1 2.7 2 1 0 2 2 2 0 AAA domain Herpes_Helicase PF02689.14 AAZ37443.1 - 0.044 11.7 0.0 0.12 10.3 0.0 1.6 2 0 0 2 2 2 0 Helicase SbcCD_C PF13558.6 AAZ37443.1 - 0.046 14.0 0.1 5.1 7.4 0.1 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 AAZ37443.1 - 0.049 13.2 1.7 2.9 7.4 0.4 3.2 2 1 0 2 2 2 0 AAA domain MobB PF03205.14 AAZ37443.1 - 0.053 13.4 0.1 3 7.7 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.18 AAZ37443.1 - 0.056 13.2 0.0 7.3 6.3 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF3987 PF13148.6 AAZ37443.1 - 0.061 12.3 0.1 4.3 6.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) SRP54 PF00448.22 AAZ37443.1 - 0.062 12.9 0.1 3.8 7.1 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Rad17 PF03215.15 AAZ37443.1 - 0.066 13.1 0.1 7.1 6.5 0.0 2.6 3 0 0 3 3 2 0 Rad17 P-loop domain cobW PF02492.19 AAZ37443.1 - 0.071 12.7 0.3 2 8.0 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 AAZ37443.1 - 0.086 12.1 0.2 3.8 6.7 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.22 AAZ37443.1 - 0.088 13.2 0.1 15 6.0 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.6 AAZ37443.1 - 0.093 13.0 0.1 5.6 7.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 AAZ37443.1 - 0.097 11.6 0.1 9.8 5.0 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_17 PF13207.6 AAZ37443.1 - 0.1 13.0 0.1 22 5.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 AAZ37443.1 - 0.2 11.4 0.1 6.6 6.5 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_15 PF13175.6 AAZ37443.1 - 0.26 10.9 0.0 22 4.6 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain ETF PF01012.21 AAZ37444.1 - 2.9e-38 131.6 15.4 4.6e-38 130.9 15.4 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 AAZ37444.1 - 1.1e-36 124.7 0.7 1.1e-36 124.7 0.7 2.1 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain TctC PF03401.14 AAZ37445.1 - 2.5e-21 76.0 0.0 3.1e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter family receptor Phosphonate-bd PF12974.7 AAZ37445.1 - 0.11 12.1 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein TIM PF00121.18 AAZ37446.1 - 4.9e-85 284.8 0.0 5.5e-85 284.6 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Na_Ca_ex PF01699.24 AAZ37447.1 - 1.5e-49 167.8 37.6 3.6e-27 95.2 12.9 2.4 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Herpes_glycop PF01528.16 AAZ37447.1 - 0.042 12.7 2.5 0.094 11.6 2.5 1.5 1 0 0 1 1 1 0 Herpesvirus glycoprotein M DUF1345 PF07077.11 AAZ37447.1 - 0.89 9.2 8.1 5.8 6.6 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1345) BPD_transp_1 PF00528.22 AAZ37448.1 - 7.8e-29 100.7 16.7 8.1e-29 100.7 14.0 2.0 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 AAZ37448.1 - 4.6e-15 55.3 0.3 4.6e-15 55.3 0.3 3.2 3 0 0 3 3 3 1 N-terminal TM domain of oligopeptide transport permease C ACP_syn_III_C PF08541.10 AAZ37449.1 - 3e-24 85.0 0.0 7.7e-24 83.7 0.0 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 AAZ37449.1 - 5.8e-19 67.7 0.0 1.2e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Chal_sti_synt_C PF02797.15 AAZ37449.1 - 0.093 12.7 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Chalcone and stilbene synthases, C-terminal domain SLT PF01464.20 AAZ37450.1 - 2.3e-25 88.6 0.0 3.8e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 Transglycosylase SLT domain MLTD_N PF06474.12 AAZ37450.1 - 1.1e-09 38.3 5.0 1.1e-09 38.3 5.0 2.2 2 0 0 2 2 2 1 MltD lipid attachment motif TetR_N PF00440.23 AAZ37451.1 - 1.1e-13 50.7 0.2 1.7e-13 50.1 0.2 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.6 AAZ37451.1 - 2.2e-05 24.7 3.8 3.2e-05 24.1 0.1 2.4 2 1 1 3 3 3 1 BetI-type transcriptional repressor, C-terminal FCD PF07729.12 AAZ37453.1 - 8.9e-24 84.3 0.5 1.6e-23 83.4 0.5 1.4 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 AAZ37453.1 - 3.4e-17 61.8 0.1 2.9e-16 58.9 0.1 2.4 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family MarR_2 PF12802.7 AAZ37453.1 - 2.8e-05 23.9 0.0 7.6e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 AAZ37453.1 - 4.4e-05 23.9 0.1 0.00016 22.1 0.0 2.0 2 0 0 2 2 1 1 Winged helix DNA-binding domain HTH_24 PF13412.6 AAZ37453.1 - 4.9e-05 22.8 0.1 0.00015 21.2 0.1 1.9 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_CodY PF08222.11 AAZ37453.1 - 0.00028 20.4 0.0 0.00066 19.2 0.0 1.6 1 0 0 1 1 1 1 CodY helix-turn-helix domain HTH_Crp_2 PF13545.6 AAZ37453.1 - 0.00034 20.5 0.0 0.00076 19.4 0.0 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain TrmB PF01978.19 AAZ37453.1 - 0.00045 20.0 0.0 0.00093 19.0 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Fe_dep_repress PF01325.19 AAZ37453.1 - 0.00059 20.0 0.0 0.0016 18.6 0.0 1.6 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_IclR PF09339.10 AAZ37453.1 - 0.00071 19.3 0.1 0.0026 17.5 0.1 2.0 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_5 PF01022.20 AAZ37453.1 - 0.0044 16.8 0.1 0.018 14.9 0.1 2.1 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_11 PF08279.12 AAZ37453.1 - 0.0052 16.7 0.2 0.023 14.6 0.0 2.1 2 0 0 2 2 2 1 HTH domain HTH_20 PF12840.7 AAZ37453.1 - 0.0061 16.6 0.2 0.021 14.9 0.2 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain Ribosomal_S25 PF03297.15 AAZ37453.1 - 0.015 15.5 0.0 0.05 13.8 0.0 1.9 2 0 0 2 2 2 0 S25 ribosomal protein HTH_36 PF13730.6 AAZ37453.1 - 0.016 15.2 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain MarR PF01047.22 AAZ37453.1 - 0.026 14.4 0.0 0.067 13.1 0.0 1.7 1 0 0 1 1 1 0 MarR family HTH_29 PF13551.6 AAZ37453.1 - 0.067 13.2 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn helix HTH_28 PF13518.6 AAZ37453.1 - 0.098 12.8 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain DHHA1 PF02272.19 AAZ37453.1 - 0.43 11.0 2.1 4.6 7.7 0.3 2.3 1 1 1 2 2 2 0 DHHA1 domain Pyr_redox_2 PF07992.14 AAZ37454.1 - 1.3e-29 103.4 0.0 2e-29 102.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 AAZ37454.1 - 4.1e-09 36.6 4.6 9.7e-09 35.5 4.6 1.7 1 0 0 1 1 1 1 BFD-like [2Fe-2S] binding domain Pyr_redox_3 PF13738.6 AAZ37454.1 - 8.7e-07 28.5 0.0 0.0031 16.8 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AAZ37454.1 - 3.6e-06 27.1 0.0 8e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SO_alpha_A3 PF17806.1 AAZ37454.1 - 9.3e-05 22.7 0.0 0.00022 21.5 0.0 1.6 1 0 0 1 1 1 1 Sarcosine oxidase A3 domain Pyr_redox PF00070.27 AAZ37454.1 - 0.00012 22.6 0.2 0.37 11.4 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AAZ37454.1 - 0.00025 20.2 0.9 0.013 14.6 0.0 2.9 3 0 0 3 3 3 1 FAD binding domain FAD_binding_3 PF01494.19 AAZ37454.1 - 0.00029 20.2 0.2 0.0007 18.9 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 AAZ37454.1 - 0.00036 19.4 0.0 0.00059 18.7 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.6 AAZ37454.1 - 0.0019 18.2 0.7 0.046 13.7 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 AAZ37454.1 - 0.0095 16.0 0.0 0.063 13.3 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.7 AAZ37454.1 - 0.0099 15.3 0.1 0.021 14.2 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 AAZ37454.1 - 0.011 16.1 0.0 0.032 14.7 0.0 1.7 2 0 0 2 2 1 0 Putative NAD(P)-binding GIDA PF01134.22 AAZ37454.1 - 0.026 13.6 0.0 0.043 12.9 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A DAO PF01266.24 AAZ37454.1 - 0.036 13.7 0.3 0.2 11.2 0.2 2.1 1 1 1 2 2 2 0 FAD dependent oxidoreductase TrkA_N PF02254.18 AAZ37454.1 - 0.054 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.17 AAZ37454.1 - 0.057 12.7 0.0 0.14 11.4 0.0 1.6 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.18 AAZ37454.1 - 0.15 11.9 0.0 0.39 10.6 0.0 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ribosomal_L2_C PF03947.18 AAZ37455.1 - 1.6e-56 190.0 3.2 2.7e-56 189.2 3.2 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 AAZ37455.1 - 9.7e-34 115.2 1.5 2e-32 111.0 1.1 2.3 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain Transposase_mut PF00872.18 AAZ37456.1 - 8.8e-117 390.2 0.0 1.1e-116 389.8 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ37456.1 - 7.7e-05 23.0 0.0 0.00021 21.6 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain Aminotran_3 PF00202.21 AAZ37457.1 - 6.5e-126 420.3 0.0 7.7e-126 420.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 AAZ37457.1 - 2.4e-06 27.0 0.0 0.0035 16.6 0.0 2.0 2 0 0 2 2 2 2 Aminotransferase class I and II GAF PF01590.26 AAZ37458.1 - 7.9e-09 36.2 0.0 1.1e-08 35.8 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 AAZ37458.1 - 1.1e-05 25.7 0.0 1.5e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 GAF domain 4HBT PF03061.22 AAZ37459.1 - 2e-17 63.3 0.1 2.7e-17 62.9 0.1 1.2 1 0 0 1 1 1 1 Thioesterase superfamily MaoC_dehydratas PF01575.19 AAZ37459.1 - 0.13 11.8 0.1 0.19 11.3 0.1 1.3 1 1 0 1 1 1 0 MaoC like domain TnsD PF15978.5 AAZ37460.1 - 0.00037 19.6 0.0 0.00049 19.2 0.0 1.2 1 0 0 1 1 1 1 Tn7-like transposition protein D HTH_29 PF13551.6 AAZ37460.1 - 0.037 14.1 0.2 3.7 7.6 0.0 2.9 3 0 0 3 3 3 0 Winged helix-turn helix RWP-RK PF02042.15 AAZ37460.1 - 0.093 12.7 0.1 2.9 8.0 0.0 3.1 3 0 0 3 3 3 0 RWP-RK domain NifU_N PF01592.16 AAZ37461.1 - 3.2e-57 192.2 0.2 3.7e-57 192.0 0.2 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain CO_deh_flav_C PF03450.17 AAZ37461.1 - 0.059 13.5 0.1 0.088 13.0 0.1 1.3 1 1 0 1 1 1 0 CO dehydrogenase flavoprotein C-terminal domain TadE PF07811.12 AAZ37462.1 - 0.012 15.9 1.4 0.013 15.8 1.4 1.1 1 0 0 1 1 1 0 TadE-like protein DUF4307 PF14155.6 AAZ37462.1 - 0.55 10.1 2.5 0.6 10.0 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) PilZ PF07238.14 AAZ37463.1 - 3.6e-15 56.1 0.0 4.2e-15 55.9 0.0 1.0 1 0 0 1 1 1 1 PilZ domain DUF3850 PF12961.7 AAZ37463.1 - 0.0026 17.8 0.0 0.2 11.7 0.0 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF3850) DUF4096 PF13340.6 AAZ37464.1 - 5.8e-25 87.3 0.4 1.5e-24 86.0 0.4 1.8 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1 PF01609.21 AAZ37464.1 - 3.2e-14 53.1 0.0 5.7e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AAZ37464.1 - 7.2e-10 39.1 0.2 2.1e-09 37.6 0.2 1.9 1 0 0 1 1 1 1 Transposase DDE domain HTH_Tnp_Tc3_2 PF01498.18 AAZ37464.1 - 0.061 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Transposase Molybdopterin PF00384.22 AAZ37465.1 - 5.6e-36 124.4 0.0 1.3e-35 123.2 0.0 1.6 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 AAZ37465.1 - 3.4e-25 88.2 0.0 7e-25 87.2 0.0 1.6 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 AAZ37465.1 - 3.3e-05 23.8 0.0 7e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain MlaD PF02470.20 AAZ37466.1 - 2.5e-36 123.8 2.8 1.8e-15 57.0 0.0 3.5 3 0 0 3 3 3 3 MlaD protein PhaP_Bmeg PF09602.10 AAZ37466.1 - 0.0002 21.4 0.6 0.00034 20.6 0.6 1.3 1 0 0 1 1 1 1 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF948 PF06103.11 AAZ37466.1 - 0.014 15.6 0.7 0.035 14.4 0.7 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Apolipoprotein PF01442.18 AAZ37466.1 - 0.021 14.7 1.1 0.043 13.7 1.1 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 AAZ37466.1 - 0.026 14.5 0.2 0.055 13.5 0.2 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.11 AAZ37466.1 - 0.09 10.7 0.1 0.13 10.2 0.1 1.1 1 0 0 1 1 1 0 Prominin AIP3 PF03915.13 AAZ37466.1 - 0.13 11.3 0.5 0.21 10.7 0.5 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 HTH_Mga PF08280.11 AAZ37466.1 - 0.13 12.3 0.1 0.27 11.3 0.1 1.4 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain SesA PF17107.5 AAZ37466.1 - 0.2 11.8 0.7 0.61 10.3 0.2 1.8 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases MscS_porin PF12795.7 AAZ37466.1 - 1.5 8.3 8.7 9.2 5.7 8.7 2.1 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain Sulf_transp PF04143.14 AAZ37467.1 - 2.7e-77 260.4 38.9 2.7e-77 260.4 38.9 1.6 2 0 0 2 2 2 1 Sulphur transport PRA1 PF03208.19 AAZ37467.1 - 0.01 15.4 0.9 0.01 15.4 0.9 3.4 2 1 1 3 3 3 0 PRA1 family protein EAL PF00563.20 AAZ37468.1 - 7.8e-75 251.4 0.0 1.2e-74 250.9 0.0 1.3 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AAZ37468.1 - 1.7e-40 138.4 0.0 3.1e-40 137.5 0.0 1.5 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Response_reg PF00072.24 AAZ37468.1 - 4.4e-28 97.7 0.1 1.2e-27 96.2 0.1 1.9 1 0 0 1 1 1 1 Response regulator receiver domain PAS PF00989.25 AAZ37468.1 - 2.5e-10 40.3 0.1 6e-10 39.1 0.1 1.7 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AAZ37468.1 - 1.9e-09 37.7 0.0 5.5e-09 36.2 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 AAZ37468.1 - 6.2e-09 35.7 0.7 6.6e-08 32.4 0.0 3.0 3 0 0 3 3 3 1 PAS domain PAS_4 PF08448.10 AAZ37468.1 - 3.8e-05 23.9 0.1 0.00011 22.4 0.1 1.8 1 0 0 1 1 1 1 PAS fold Band_7 PF01145.25 AAZ37469.1 - 1.7e-31 109.6 0.4 5.1e-31 108.1 0.0 1.8 2 0 0 2 2 2 1 SPFH domain / Band 7 family 2-Hacid_dh_C PF02826.19 AAZ37470.1 - 1.3e-34 119.1 0.0 2.3e-34 118.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF3410 PF11890.8 AAZ37470.1 - 2.5e-23 81.7 0.0 4.4e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3410) 2-Hacid_dh PF00389.30 AAZ37470.1 - 2.3e-16 59.7 0.0 3.1e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.6 AAZ37470.1 - 6e-05 23.5 0.0 0.00011 22.7 0.0 1.4 1 0 0 1 1 1 1 XdhC Rossmann domain TrkA_N PF02254.18 AAZ37470.1 - 0.13 12.5 0.0 0.34 11.2 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain LPAM_1 PF08139.12 AAZ37471.1 - 2.3 8.9 4.1 4 8.1 4.1 1.4 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site LysR_substrate PF03466.20 AAZ37472.1 - 1.6e-35 122.4 0.1 2.6e-35 121.7 0.1 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ37472.1 - 1.1e-20 73.3 0.6 1.9e-20 72.5 0.6 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_5 PF01022.20 AAZ37472.1 - 0.0057 16.5 0.2 0.023 14.5 0.0 1.9 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 AAZ37472.1 - 0.017 15.2 0.6 2.4 8.3 0.1 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_30 PF13556.6 AAZ37472.1 - 0.032 14.0 0.0 0.069 13.0 0.0 1.5 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_28 PF13518.6 AAZ37472.1 - 0.097 12.8 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Head-tail_con PF12236.8 AAZ37472.1 - 0.14 10.6 0.0 0.2 10.1 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage head to tail connecting protein HTH_24 PF13412.6 AAZ37472.1 - 0.16 11.6 0.0 0.36 10.4 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding SBP_bac_8 PF13416.6 AAZ37473.1 - 1.2e-10 41.7 6.5 2.7e-10 40.5 6.5 1.6 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein Cloacin_immun PF03513.14 AAZ37473.1 - 0.058 13.7 0.2 1.4 9.3 0.1 2.6 2 0 0 2 2 2 0 Cloacin immunity protein APS_kinase PF01583.20 AAZ37474.1 - 1.9e-48 164.3 0.0 3.4e-48 163.5 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase GTP_EFTU PF00009.27 AAZ37474.1 - 4.9e-45 153.5 0.1 1.1e-44 152.4 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 AAZ37474.1 - 2.3e-09 37.3 0.1 1.2e-05 25.4 0.0 3.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 AAZ37474.1 - 2e-07 31.3 0.5 9.5e-07 29.1 0.2 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 AAA_33 PF13671.6 AAZ37474.1 - 2e-06 28.0 0.0 2.2e-05 24.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 AAZ37474.1 - 4.9e-05 22.7 0.0 8.3e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.6 AAZ37474.1 - 0.00063 19.4 0.0 0.055 13.2 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AAZ37474.1 - 0.00064 20.1 0.0 0.0026 18.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 AAZ37474.1 - 0.0007 19.5 0.1 0.63 9.9 0.0 3.3 3 1 0 3 3 3 1 RsgA GTPase AAA_18 PF13238.6 AAZ37474.1 - 0.0016 19.0 0.1 0.0077 16.8 0.0 2.3 2 1 0 2 2 1 1 AAA domain G-alpha PF00503.20 AAZ37474.1 - 0.0054 15.9 0.1 1 8.5 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit Roc PF08477.13 AAZ37474.1 - 0.0054 16.9 0.1 5.6 7.2 0.0 3.3 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase IstB_IS21 PF01695.17 AAZ37474.1 - 0.006 16.3 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein ABC_tran PF00005.27 AAZ37474.1 - 0.023 15.2 0.0 0.14 12.7 0.0 2.1 2 0 0 2 2 2 0 ABC transporter CbiA PF01656.23 AAZ37474.1 - 0.037 14.1 0.0 0.096 12.8 0.0 1.8 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain SRPRB PF09439.10 AAZ37474.1 - 0.037 13.4 0.1 1.3 8.4 0.0 2.8 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit GTP_EFTU_D3 PF03143.17 AAZ37474.1 - 0.053 13.8 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 Elongation factor Tu C-terminal domain Sigma54_activat PF00158.26 AAZ37474.1 - 0.058 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain KTI12 PF08433.10 AAZ37474.1 - 0.13 11.7 0.0 0.31 10.5 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA PF00004.29 AAZ37474.1 - 0.16 12.4 0.0 0.43 11.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UPF0047 PF01894.17 AAZ37475.1 - 6.3e-35 119.8 0.0 7e-35 119.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 PAPS_reduct PF01507.19 AAZ37477.1 - 1.4e-12 48.0 0.0 2.3e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family T2SSE PF00437.20 AAZ37478.1 - 1.5e-36 125.9 0.1 2.6e-36 125.1 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 AAZ37478.1 - 0.00049 20.6 0.0 0.00086 19.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 AAZ37478.1 - 0.00087 18.7 0.0 0.0017 17.8 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_23 PF13476.6 AAZ37478.1 - 0.0022 18.6 0.0 0.0066 17.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AAZ37478.1 - 0.0024 18.3 0.0 0.0046 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AAZ37478.1 - 0.0039 16.9 0.1 0.0091 15.7 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AAZ37478.1 - 0.006 16.9 0.1 0.019 15.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 AAZ37478.1 - 0.0077 16.7 0.0 0.014 15.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 AAZ37478.1 - 0.012 15.1 0.0 0.033 13.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF87 PF01935.17 AAZ37478.1 - 0.013 15.6 0.7 0.031 14.4 0.6 1.7 1 1 0 1 1 1 0 Helicase HerA, central domain AAA_33 PF13671.6 AAZ37478.1 - 0.02 15.1 0.1 0.042 14.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 AAZ37478.1 - 0.025 14.6 0.0 0.038 14.0 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 AAZ37478.1 - 0.026 13.4 0.0 0.047 12.6 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain SRP54 PF00448.22 AAZ37478.1 - 0.03 14.0 0.0 0.062 12.9 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_30 PF13604.6 AAZ37478.1 - 0.036 13.8 0.1 0.12 12.0 0.1 1.9 1 1 1 2 2 2 0 AAA domain Zeta_toxin PF06414.12 AAZ37478.1 - 0.043 13.1 0.0 0.082 12.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 AAZ37478.1 - 0.12 12.0 0.3 0.23 11.0 0.3 1.5 1 1 0 1 1 1 0 AAA domain DAP3 PF10236.9 AAZ37478.1 - 0.18 10.9 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 DUF2141 PF09912.9 AAZ37478.1 - 0.19 11.6 0.0 0.78 9.7 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2141) SseC PF04888.12 AAZ37479.1 - 3.1 7.3 9.4 4.2 6.9 9.4 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family RraA-like PF03737.15 AAZ37480.1 - 1.2e-42 145.6 0.2 1.3e-42 145.5 0.2 1.0 1 0 0 1 1 1 1 Aldolase/RraA DDE_Tnp_1 PF01609.21 AAZ37481.1 - 6.3e-36 124.0 1.1 9.7e-36 123.4 0.8 1.4 2 0 0 2 2 2 1 Transposase DDE domain DUF772 PF05598.11 AAZ37481.1 - 2.8e-19 68.9 0.1 5.6e-19 67.9 0.1 1.5 1 0 0 1 1 1 1 Transposase domain (DUF772) DDE_Tnp_1_6 PF13751.6 AAZ37481.1 - 4.7e-07 30.1 0.6 8.4e-07 29.3 0.6 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 AAZ37481.1 - 1.3e-05 25.2 0.1 2.1e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 AAZ37481.1 - 0.00042 20.0 0.7 0.00069 19.3 0.7 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1_2 PF13586.6 AAZ37481.1 - 0.012 16.0 0.8 0.024 15.0 0.8 1.5 1 0 0 1 1 1 0 Transposase DDE domain Aminotran_4 PF01063.19 AAZ37482.1 - 3.6e-39 134.9 0.0 4.4e-39 134.6 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV DUF4096 PF13340.6 AAZ37484.1 - 5.8e-25 87.3 0.4 1.5e-24 86.0 0.4 1.8 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1 PF01609.21 AAZ37484.1 - 3.2e-14 53.1 0.0 5.7e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AAZ37484.1 - 7.2e-10 39.1 0.2 2.1e-09 37.6 0.2 1.9 1 0 0 1 1 1 1 Transposase DDE domain HTH_Tnp_Tc3_2 PF01498.18 AAZ37484.1 - 0.061 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Transposase Amino_oxidase PF01593.24 AAZ37485.1 - 4.1e-24 85.7 2.8 5.1e-12 45.8 0.2 2.0 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 AAZ37485.1 - 5.6e-15 55.3 0.5 1.3e-14 54.2 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AAZ37485.1 - 1.3e-05 24.6 0.0 5.6e-05 22.5 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AAZ37485.1 - 4.6e-05 22.7 0.9 4.6e-05 22.7 0.9 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 AAZ37485.1 - 0.00011 22.2 0.2 0.0013 18.7 0.0 2.6 2 1 0 2 2 2 1 FAD-NAD(P)-binding ApbA PF02558.16 AAZ37485.1 - 0.00013 21.6 0.0 0.036 13.7 0.1 2.2 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA DAO PF01266.24 AAZ37485.1 - 0.00014 21.6 2.4 0.00035 20.3 1.6 1.8 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 AAZ37485.1 - 0.00037 19.9 0.1 0.00059 19.2 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 AAZ37485.1 - 0.00068 19.1 0.0 0.00097 18.6 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 AAZ37485.1 - 0.00076 18.3 0.1 0.0011 17.7 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 AAZ37485.1 - 0.0014 17.8 0.1 0.0019 17.4 0.1 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 AAZ37485.1 - 0.0019 17.5 0.1 0.0028 17.0 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 AAZ37485.1 - 0.0024 17.8 0.1 0.0035 17.3 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 AAZ37485.1 - 0.004 17.7 0.0 0.0074 16.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 AAZ37485.1 - 0.013 15.6 0.0 0.02 15.0 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Thi4 PF01946.17 AAZ37485.1 - 0.043 13.1 0.2 0.067 12.4 0.2 1.3 1 0 0 1 1 1 0 Thi4 family MCRA PF06100.11 AAZ37485.1 - 0.056 12.2 0.1 0.078 11.8 0.1 1.1 1 0 0 1 1 1 0 MCRA family UDPG_MGDP_dh_N PF03721.14 AAZ37485.1 - 0.057 13.0 0.0 0.087 12.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.23 AAZ37485.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF2934 PF11154.8 AAZ37486.1 - 9.6e-14 50.8 4.5 1.4e-13 50.2 4.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2934) Ribosomal_L22e PF01776.17 AAZ37487.1 - 0.054 13.9 0.1 2.4 8.6 0.0 2.1 2 0 0 2 2 2 0 Ribosomal L22e protein family DUF1015 PF06245.11 AAZ37489.1 - 0.039 12.8 0.4 0.16 10.8 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1015) ChW PF07538.11 AAZ37490.1 - 0.0063 16.4 0.1 2.8 8.0 0.0 2.6 2 0 0 2 2 2 2 Clostridial hydrophobic W Abhydrolase_1 PF00561.20 AAZ37491.1 - 2e-35 122.7 0.2 4e-35 121.7 0.2 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AAZ37491.1 - 1.1e-15 57.6 0.0 2.2e-15 56.6 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AAZ37491.1 - 6.1e-15 56.4 3.7 7.8e-15 56.1 3.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 AAZ37491.1 - 0.00025 19.8 0.0 0.00036 19.3 0.0 1.2 1 0 0 1 1 1 1 Ndr family Abhydrolase_4 PF08386.10 AAZ37491.1 - 0.0026 17.8 0.0 0.005 16.9 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Ser_hydrolase PF06821.13 AAZ37491.1 - 0.0061 16.4 0.0 0.022 14.6 0.0 1.8 2 0 0 2 2 2 1 Serine hydrolase LIP PF03583.14 AAZ37491.1 - 0.013 14.8 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Secretory lipase Peptidase_S28 PF05577.12 AAZ37491.1 - 0.033 13.0 0.0 0.055 12.3 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Peptidase_S15 PF02129.18 AAZ37491.1 - 0.045 13.3 0.2 0.096 12.3 0.2 1.6 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 AAZ37491.1 - 0.091 12.4 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Bac_DNA_binding PF00216.21 AAZ37492.1 - 5.3e-31 106.7 0.2 5.9e-31 106.5 0.2 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 AAZ37492.1 - 2.2e-06 27.8 0.0 2.6e-06 27.6 0.0 1.0 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_bac_2 PF18175.1 AAZ37492.1 - 1.1e-05 25.1 0.1 1.7e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 CCDC81-like prokaryotic HU domain 2 HU-CCDC81_euk_2 PF18289.1 AAZ37492.1 - 0.055 13.6 0.0 0.08 13.1 0.0 1.2 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 2 Meth_synt_1 PF08267.12 AAZ37492.1 - 0.085 12.3 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 Cobalamin-independent synthase, N-terminal domain ABC2_membrane PF01061.24 AAZ37493.1 - 3.6e-28 98.4 21.3 3.6e-28 98.4 21.3 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 AAZ37493.1 - 0.44 9.6 23.6 0.1 11.7 20.4 1.5 1 1 1 2 2 2 0 ABC-2 family transporter protein DUF4096 PF13340.6 AAZ37494.1 - 5.9e-25 87.3 0.4 1.5e-24 86.0 0.4 1.7 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1 PF01609.21 AAZ37494.1 - 5.5e-14 52.3 0.0 9.7e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AAZ37494.1 - 2.4e-08 34.2 0.1 7.4e-08 32.7 0.1 1.9 1 0 0 1 1 1 1 Transposase DDE domain HTH_Tnp_Tc3_2 PF01498.18 AAZ37494.1 - 0.063 13.5 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Transposase Poly_export PF02563.16 AAZ37495.1 - 3.3e-21 75.3 0.2 1.5e-20 73.2 0.1 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis/export protein SLBB PF10531.9 AAZ37495.1 - 4.8e-06 26.3 0.2 1.6e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 SLBB domain Wza_C PF18412.1 AAZ37495.1 - 0.0023 17.7 0.0 0.0055 16.4 0.0 1.7 1 0 0 1 1 1 1 Outer-membrane lipoprotein Wza C-terminal domain Aldo_ket_red PF00248.21 AAZ37496.1 - 5.5e-68 229.3 0.0 6.3e-68 229.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family B12-binding PF02310.19 AAZ37496.1 - 0.11 12.6 0.0 5.9 6.9 0.0 2.7 2 1 1 3 3 3 0 B12 binding domain zf-C4_Topoisom PF01396.19 AAZ37497.1 - 2.1e-08 33.8 1.8 3.5e-08 33.1 1.8 1.3 1 0 0 1 1 1 1 Topoisomerase DNA binding C4 zinc finger ATG16 PF08614.11 AAZ37497.1 - 0.041 14.1 1.2 0.047 13.9 1.2 1.0 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) zf-GRF PF06839.12 AAZ37497.1 - 2.1 8.5 5.4 0.33 11.1 1.5 1.7 2 0 0 2 2 2 0 GRF zinc finger ACR_tran PF00873.19 AAZ37498.1 - 0 1154.8 24.2 0 1154.6 24.2 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family EamA PF00892.20 AAZ37500.1 - 9.1e-22 77.7 39.8 1.5e-17 64.1 15.6 2.4 2 1 0 2 2 2 2 EamA-like transporter family FAD_binding_3 PF01494.19 AAZ37501.1 - 4.4e-92 309.0 0.0 5.1e-92 308.8 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 AAZ37501.1 - 0.00062 19.1 0.0 0.0083 15.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AAZ37501.1 - 0.0014 18.8 0.0 0.0034 17.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AAZ37501.1 - 0.14 11.4 0.0 0.25 10.5 0.0 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAZ37501.1 - 0.18 12.4 0.0 0.32 11.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 AAZ37502.1 - 1.1e-26 93.6 79.7 1.3e-25 90.1 48.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AAZ37502.1 - 6.6e-18 64.8 35.8 1.4e-16 60.5 9.3 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter Response_reg PF00072.24 AAZ37503.1 - 1.6e-28 99.1 0.0 2.2e-28 98.7 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAZ37503.1 - 1.5e-22 79.4 0.2 3.1e-22 78.4 0.2 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal CN_hydrolase PF00795.22 AAZ37504.1 - 5.7e-07 29.1 0.0 1.4e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Methyltrans_RNA PF04452.14 AAZ37505.1 - 5.2e-72 241.8 0.0 5.9e-72 241.7 0.0 1.0 1 0 0 1 1 1 1 RNA methyltransferase ProQ_C PF17516.2 AAZ37505.1 - 0.11 11.9 0.1 0.3 10.5 0.0 1.7 2 0 0 2 2 2 0 ProQ C-terminal domain DnaJ PF00226.31 AAZ37506.1 - 6.7e-19 67.8 0.4 1.2e-18 67.0 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain Viral_DNA_bp PF00747.17 AAZ37506.1 - 0.13 9.4 0.1 0.18 9.0 0.1 1.1 1 0 0 1 1 1 0 ssDNA binding protein Lyase_1 PF00206.20 AAZ37507.1 - 7.1e-78 262.1 0.0 1e-77 261.6 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 AAZ37507.1 - 4.3e-26 91.5 0.0 1e-25 90.3 0.0 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal DUF2205 PF10224.9 AAZ37507.1 - 0.026 14.5 0.0 0.078 13.0 0.0 1.7 1 0 0 1 1 1 0 Short coiled-coil protein K-box PF01486.17 AAZ37507.1 - 0.13 12.4 0.1 0.4 10.9 0.1 1.7 1 0 0 1 1 1 0 K-box region ABC_tran PF00005.27 AAZ37508.1 - 1.2e-49 168.3 0.0 2.9e-25 89.4 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 AAZ37508.1 - 2.8e-11 43.8 0.0 0.0016 18.3 0.0 3.1 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 AAZ37508.1 - 0.0017 18.3 0.0 0.55 10.1 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 AAZ37508.1 - 0.004 16.9 0.6 1.1 8.9 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 AAZ37508.1 - 0.004 17.4 1.3 0.5 10.6 0.1 3.4 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.6 AAZ37508.1 - 0.0073 16.7 0.6 1.6 9.1 0.0 2.8 3 1 0 3 3 2 1 AAA ATPase domain AAA_29 PF13555.6 AAZ37508.1 - 0.0073 16.0 0.0 0.034 13.9 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 AAZ37508.1 - 0.042 14.4 0.1 1.5 9.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 AAZ37508.1 - 0.058 13.9 0.1 0.13 12.7 0.0 1.5 2 0 0 2 2 1 0 AAA domain ABC_ATPase PF09818.9 AAZ37508.1 - 0.075 11.8 3.1 9.4 4.9 0.0 3.7 3 1 1 4 4 4 0 Predicted ATPase of the ABC class AAA_15 PF13175.6 AAZ37508.1 - 0.091 12.5 0.1 0.25 11.0 0.1 1.6 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.23 AAZ37508.1 - 0.11 12.6 0.0 4.8 7.3 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase MeaB PF03308.16 AAZ37508.1 - 0.11 11.4 0.6 7.5 5.4 0.1 2.6 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SMC_N PF02463.19 AAZ37508.1 - 0.11 11.9 0.8 8 5.8 0.0 2.7 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_7 PF12775.7 AAZ37508.1 - 0.11 12.0 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 AAZ37508.1 - 0.16 12.4 1.5 12 6.4 0.0 2.9 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 AAZ37508.1 - 0.2 11.8 0.1 5.9 7.1 0.1 2.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 AAZ37508.1 - 0.22 11.2 1.9 8.8 6.0 0.1 3.3 4 0 0 4 4 4 0 IstB-like ATP binding protein ACT_7 PF13840.6 AAZ37508.1 - 0.25 11.1 1.0 1.6 8.6 0.1 2.8 4 0 0 4 4 3 0 ACT domain Sigma54_activat PF00158.26 AAZ37509.1 - 4.6e-67 224.9 0.1 6.4e-67 224.5 0.1 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain Response_reg PF00072.24 AAZ37509.1 - 3.1e-27 94.9 0.0 6.1e-27 94.0 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Sigma54_activ_2 PF14532.6 AAZ37509.1 - 1.4e-24 86.8 0.0 4.6e-23 81.9 0.0 2.7 2 1 0 2 2 2 1 Sigma-54 interaction domain HTH_50 PF18024.1 AAZ37509.1 - 1.3e-08 34.3 0.0 2.7e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain AAA_5 PF07728.14 AAZ37509.1 - 1.5e-08 34.8 0.0 5.9e-08 32.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 AAZ37509.1 - 1.1e-05 25.7 0.0 1.7e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) FleQ PF06490.11 AAZ37509.1 - 4e-05 24.0 0.0 7.8e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Flagellar regulatory protein FleQ HTH_8 PF02954.19 AAZ37509.1 - 0.00013 21.7 0.1 0.00045 20.0 0.0 2.1 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family Mg_chelatase PF01078.21 AAZ37509.1 - 0.00082 18.8 0.1 0.48 9.8 0.0 2.2 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA PF00004.29 AAZ37509.1 - 0.0012 19.3 0.0 0.0021 18.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TadZ_N PF16968.5 AAZ37509.1 - 0.02 14.6 0.1 0.97 9.1 0.0 2.4 2 0 0 2 2 2 0 Pilus assembly protein TadZ N-terminal HTH_43 PF09904.9 AAZ37509.1 - 0.045 13.7 0.0 0.19 11.7 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn helix HTH_23 PF13384.6 AAZ37509.1 - 0.51 10.2 0.0 0.51 10.2 0.0 2.3 3 0 0 3 3 3 0 Homeodomain-like domain ABC_tran PF00005.27 AAZ37510.1 - 7.1e-45 152.9 0.0 3.6e-32 111.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 AAZ37510.1 - 8.2e-05 22.6 0.8 0.084 12.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AAZ37510.1 - 0.0014 18.3 0.0 0.0049 16.6 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 AAZ37510.1 - 0.057 13.1 0.7 0.26 11.0 0.1 2.4 2 1 0 2 2 2 0 AAA domain AAA_27 PF13514.6 AAZ37510.1 - 0.087 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AAZ37510.1 - 0.12 12.8 0.0 0.19 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 AAZ37510.1 - 0.18 11.7 0.2 0.96 9.3 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase MukB PF04310.12 AAZ37510.1 - 0.19 11.5 0.0 0.41 10.4 0.0 1.5 1 0 0 1 1 1 0 MukB N-terminal MFS_1 PF07690.16 AAZ37511.1 - 2.1e-23 82.8 48.0 2.1e-23 82.8 48.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Response_reg PF00072.24 AAZ37512.1 - 5.5e-20 71.6 0.0 1.1e-19 70.7 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 AAZ37512.1 - 2.3e-12 47.4 0.0 4.3e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_4 PF08448.10 AAZ37512.1 - 9.8e-12 45.1 0.1 3.7e-05 23.9 0.0 3.6 4 1 0 4 4 4 2 PAS fold PAS_3 PF08447.12 AAZ37512.1 - 1.1e-10 41.6 0.1 4.8e-10 39.6 0.0 2.1 3 0 0 3 3 3 1 PAS fold PAS PF00989.25 AAZ37512.1 - 4.9e-09 36.2 0.1 1.4e-07 31.5 0.0 2.9 3 0 0 3 3 3 1 PAS fold HisKA PF00512.25 AAZ37512.1 - 1.2e-07 31.6 0.7 1.2e-07 31.6 0.7 2.9 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 AAZ37512.1 - 6.5e-07 29.6 0.0 9.8e-05 22.6 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.7 AAZ37512.1 - 1.3e-05 25.1 0.1 0.00028 20.8 0.0 2.8 2 0 0 2 2 2 1 PAS domain PAS_11 PF14598.6 AAZ37512.1 - 0.0002 21.4 0.0 0.00047 20.3 0.0 1.6 1 0 0 1 1 1 1 PAS domain HPTransfase PF10090.9 AAZ37512.1 - 0.054 13.3 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Histidine phosphotransferase C-terminal domain Fimbrial PF00419.20 AAZ37513.1 - 2.3e-09 37.7 0.0 4.2e-08 33.6 0.0 2.1 2 0 0 2 2 2 1 Fimbrial protein ABC_tran PF00005.27 AAZ37514.1 - 3.8e-47 160.2 0.0 2e-24 86.6 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 AAZ37514.1 - 1.5e-09 38.1 0.8 0.015 15.1 0.4 3.3 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 AAZ37514.1 - 0.00047 20.1 0.2 0.055 13.4 0.0 2.8 3 0 0 3 3 3 1 RsgA GTPase SbcCD_C PF13558.6 AAZ37514.1 - 0.0012 19.1 2.3 3.3 8.0 0.0 3.7 3 1 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 AAZ37514.1 - 0.022 14.5 0.7 0.57 9.9 0.2 3.2 3 1 0 3 3 3 0 AAA domain AAA_29 PF13555.6 AAZ37514.1 - 0.027 14.2 0.0 2.4 8.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_33 PF13671.6 AAZ37514.1 - 0.04 14.1 4.9 8.6 6.5 0.0 4.1 3 2 0 3 3 3 0 AAA domain TsaE PF02367.17 AAZ37514.1 - 0.078 13.0 0.0 14 5.7 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ACR_tran PF00873.19 AAZ37515.1 - 0 1342.1 14.8 0 1341.9 14.8 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family SecD_SecF PF02355.16 AAZ37515.1 - 2.4e-06 27.1 30.5 0.0017 17.8 16.7 2.7 2 0 0 2 2 2 2 Protein export membrane protein Piezo_RRas_bdg PF12166.8 AAZ37515.1 - 0.39 10.0 2.3 0.59 9.4 0.3 2.2 2 0 0 2 2 2 0 Piezo non-specific cation channel, R-Ras-binding domain ACP_syn_III_C PF08541.10 AAZ37516.1 - 1.9e-31 108.1 0.0 3.1e-31 107.4 0.0 1.4 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 AAZ37516.1 - 2e-22 78.9 0.0 3.2e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Chal_sti_synt_N PF00195.19 AAZ37516.1 - 1.8e-06 27.5 0.0 2.7e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Thiolase_N PF00108.23 AAZ37516.1 - 2.1e-05 24.0 0.0 3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain FAE1_CUT1_RppA PF08392.12 AAZ37516.1 - 0.0019 17.6 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein CASP_C PF08172.12 AAZ37517.1 - 0.00082 18.8 0.3 0.0014 18.0 0.3 1.3 1 0 0 1 1 1 1 CASP C terminal Seryl_tRNA_N PF02403.22 AAZ37517.1 - 0.012 15.8 4.9 0.042 14.1 0.7 2.8 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FapA PF03961.13 AAZ37517.1 - 0.028 13.0 4.7 0.48 9.0 0.6 2.2 1 1 0 2 2 2 0 Flagellar Assembly Protein A ING PF12998.7 AAZ37517.1 - 0.03 14.9 2.4 2.4 8.8 0.0 3.3 2 1 1 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding P22_AR_N PF10547.9 AAZ37517.1 - 0.079 13.3 0.0 0.27 11.6 0.0 1.9 1 0 0 1 1 1 0 P22_AR N-terminal domain DHR10 PF18595.1 AAZ37517.1 - 0.088 12.9 0.2 0.088 12.9 0.2 3.1 3 1 0 3 3 3 0 Designed helical repeat protein 10 domain BORCS6 PF10157.9 AAZ37517.1 - 0.13 12.5 3.3 0.53 10.5 0.3 2.5 1 1 1 2 2 2 0 BLOC-1-related complex sub-unit 6 CK2S PF15011.6 AAZ37517.1 - 0.14 12.1 6.2 0.046 13.6 0.8 2.3 1 1 1 2 2 2 0 Casein Kinase 2 substrate APG6_N PF17675.1 AAZ37517.1 - 0.14 12.6 5.7 1.1 9.8 0.4 2.7 2 1 0 2 2 2 0 Apg6 coiled-coil region DUF16 PF01519.16 AAZ37517.1 - 0.28 11.7 3.6 4.2 7.9 0.4 2.9 1 1 1 2 2 2 0 Protein of unknown function DUF16 Acetyltransf_11 PF13720.6 AAZ37517.1 - 0.49 10.9 2.1 0.65 10.5 0.2 2.1 3 0 0 3 3 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 GAS PF13851.6 AAZ37517.1 - 0.53 9.6 7.0 0.32 10.3 1.2 2.6 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding SKA2 PF16740.5 AAZ37517.1 - 1.6 8.5 7.0 1.7 8.4 0.4 3.1 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 HIP1_clath_bdg PF16515.5 AAZ37517.1 - 1.9 9.1 6.2 1.3 9.7 1.0 2.8 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4140 PF13600.6 AAZ37517.1 - 2.2 8.8 6.1 25 5.4 0.2 3.1 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Dict-STAT-coil PF09267.10 AAZ37517.1 - 4.9 7.6 7.7 0.86 10.0 0.3 2.8 2 1 0 2 2 2 0 Dictyostelium STAT, coiled coil ABC_tran PF00005.27 AAZ37518.1 - 1.2e-21 77.6 0.0 1.7e-21 77.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAZ37518.1 - 0.00051 20.0 1.7 0.048 13.5 0.4 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 AAZ37518.1 - 0.00057 20.2 1.0 0.013 15.7 1.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAZ37518.1 - 0.0039 17.6 0.8 0.013 15.9 0.8 1.9 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 AAZ37518.1 - 0.01 15.6 0.2 0.08 12.7 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_33 PF13671.6 AAZ37518.1 - 0.023 14.9 0.0 0.043 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 AAZ37518.1 - 0.034 14.2 0.1 0.063 13.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 AAZ37518.1 - 0.037 13.4 0.0 0.067 12.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SMC_N PF02463.19 AAZ37518.1 - 0.065 12.7 0.2 1.1 8.6 0.2 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 AAZ37518.1 - 0.079 13.0 0.2 0.13 12.3 0.2 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain Sigma54_activat PF00158.26 AAZ37518.1 - 0.17 11.6 0.1 0.27 10.9 0.1 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.6 AAZ37518.1 - 0.2 11.4 0.1 0.43 10.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Aldolase_II PF00596.21 AAZ37519.1 - 8.6e-46 156.2 0.9 1.1e-45 155.9 0.9 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF772 PF05598.11 AAZ37520.1 - 6.3e-27 93.4 0.1 1.1e-26 92.7 0.1 1.4 1 0 0 1 1 1 1 Transposase domain (DUF772) PALP PF00291.25 AAZ37521.1 - 1.9e-52 178.5 0.0 3.4e-52 177.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme OCD_Mu_crystall PF02423.15 AAZ37521.1 - 1.1e-31 109.9 0.0 1.9e-31 109.2 0.0 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 AAZ37521.1 - 4.1e-05 23.6 0.0 0.0016 18.5 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 AAZ37521.1 - 0.00055 20.5 0.0 0.0018 18.8 0.0 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 AAZ37521.1 - 0.0037 17.5 0.0 0.019 15.3 0.0 2.2 3 0 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain PhnI PF05861.12 AAZ37522.1 - 3.4e-164 545.8 0.0 3.9e-164 545.7 0.0 1.0 1 0 0 1 1 1 1 Bacterial phosphonate metabolism protein (PhnI) PhnG PF06754.12 AAZ37522.1 - 0.0027 17.6 0.0 0.0046 16.9 0.0 1.5 1 0 0 1 1 1 1 Phosphonate metabolism protein PhnG ACP PF06857.11 AAZ37523.1 - 3.2e-23 81.7 0.0 3.6e-23 81.6 0.0 1.0 1 0 0 1 1 1 1 Malonate decarboxylase delta subunit (MdcD) MazG PF03819.17 AAZ37524.1 - 1.3e-39 134.2 0.8 4.9e-27 93.9 0.0 2.5 2 0 0 2 2 2 2 MazG nucleotide pyrophosphohydrolase domain PRA-PH PF01503.17 AAZ37524.1 - 2.6e-13 50.2 2.7 5.6e-07 29.9 0.1 3.1 3 0 0 3 3 3 2 Phosphoribosyl-ATP pyrophosphohydrolase MazG-like PF12643.7 AAZ37524.1 - 0.0027 17.9 0.1 0.013 15.7 0.0 2.1 2 0 0 2 2 2 1 MazG-like family CorA PF01544.18 AAZ37524.1 - 0.21 10.8 0.1 0.38 10.0 0.1 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein PKS_DE PF18369.1 AAZ37524.1 - 0.36 11.4 2.7 2.5 8.7 0.1 3.3 3 0 0 3 3 3 0 Polyketide synthase dimerisation element domain Rhodanese PF00581.20 AAZ37525.1 - 1.5e-28 99.4 0.0 6.2e-16 58.9 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain AI-2E_transport PF01594.16 AAZ37526.1 - 1.4e-55 188.8 29.5 1.7e-55 188.5 29.5 1.0 1 0 0 1 1 1 1 AI-2E family transporter OSCP PF00213.18 AAZ37526.1 - 0.14 12.3 0.0 0.22 11.7 0.0 1.2 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit PHO4 PF01384.20 AAZ37526.1 - 1.5 7.8 14.5 23 3.9 14.5 2.1 1 1 0 1 1 1 0 Phosphate transporter family ABC_tran PF00005.27 AAZ37527.1 - 1.1e-26 93.9 0.0 1.5e-26 93.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAZ37527.1 - 3.9e-10 40.0 1.0 0.00042 20.2 0.1 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AAZ37527.1 - 0.00027 21.4 0.3 0.00041 20.8 0.3 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AAZ37527.1 - 0.00032 20.4 0.0 0.00067 19.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 AAZ37527.1 - 0.00036 20.3 0.0 0.0019 18.0 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_27 PF13514.6 AAZ37527.1 - 0.0038 16.9 0.0 0.0073 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 AAZ37527.1 - 0.0083 16.7 0.0 0.013 16.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AAZ37527.1 - 0.01 16.1 0.3 0.078 13.3 0.3 2.0 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 AAZ37527.1 - 0.014 15.1 0.0 0.072 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain SMC_N PF02463.19 AAZ37527.1 - 0.015 14.7 0.1 0.061 12.8 0.1 1.9 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.18 AAZ37527.1 - 0.016 14.6 0.0 2.5 7.4 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 AAZ37527.1 - 0.05 13.5 0.1 0.081 12.8 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_28 PF13521.6 AAZ37527.1 - 0.064 13.5 0.1 0.11 12.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 AAZ37527.1 - 0.076 12.0 0.1 0.093 11.7 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 AAZ37527.1 - 0.078 13.5 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain MukB PF04310.12 AAZ37527.1 - 0.092 12.5 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 MukB N-terminal Rad17 PF03215.15 AAZ37527.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain ABC_ATPase PF09818.9 AAZ37527.1 - 0.15 10.8 0.0 2.5 6.8 0.0 2.0 2 0 0 2 2 2 0 Predicted ATPase of the ABC class SurA_N_3 PF13624.6 AAZ37528.1 - 1.9e-42 144.8 9.3 1.9e-42 144.8 9.3 3.7 4 0 0 4 4 4 1 SurA N-terminal domain SurA_N_2 PF13623.6 AAZ37528.1 - 4.4e-33 114.2 5.8 4.4e-33 114.2 5.8 2.9 3 1 1 4 4 4 1 SurA N-terminal domain Rotamase_3 PF13616.6 AAZ37528.1 - 9e-29 100.4 0.0 9e-29 100.4 0.0 2.7 3 0 0 3 3 3 1 PPIC-type PPIASE domain Rotamase PF00639.21 AAZ37528.1 - 6.3e-28 97.6 4.2 8.1e-28 97.2 0.0 3.2 4 0 0 4 4 4 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 AAZ37528.1 - 5.6e-24 85.3 28.5 1.9e-15 57.8 1.6 5.4 4 1 1 5 5 5 4 PPIC-type PPIASE domain SurA_N PF09312.11 AAZ37528.1 - 9e-05 22.5 7.3 0.00011 22.2 2.0 3.3 2 1 1 3 3 3 1 SurA N-terminal domain Ribosomal_S14 PF00253.21 AAZ37528.1 - 0.16 11.7 0.1 0.38 10.5 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein S14p/S29e SBP_bac_5 PF00496.22 AAZ37529.1 - 5.6e-73 246.1 0.1 8.7e-73 245.4 0.1 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle GARS_A PF01071.19 AAZ37530.1 - 2.3e-82 275.5 0.1 3.1e-82 275.0 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 AAZ37530.1 - 1e-33 116.0 0.1 2.3e-33 114.8 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 AAZ37530.1 - 4.2e-28 97.4 1.2 1.7e-27 95.5 0.3 2.4 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain ATP-grasp_3 PF02655.14 AAZ37530.1 - 6.2e-05 23.1 0.0 0.00017 21.6 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 AAZ37530.1 - 7e-05 22.4 0.0 0.0001 21.9 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 AAZ37530.1 - 0.00019 21.0 0.0 0.00034 20.2 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 AAZ37530.1 - 0.012 15.2 0.0 0.032 13.8 0.0 1.8 1 1 0 1 1 1 0 ATP-grasp domain TarH PF02203.15 AAZ37531.1 - 8.7e-05 22.5 0.1 0.00011 22.1 0.1 1.2 1 0 0 1 1 1 1 Tar ligand binding domain homologue ATP-synt_E PF05680.12 AAZ37531.1 - 0.015 15.6 0.0 0.023 15.0 0.0 1.2 1 0 0 1 1 1 0 ATP synthase E chain tRNA-synt_1 PF00133.22 AAZ37532.1 - 8.3e-196 651.8 0.0 9.9e-196 651.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 AAZ37532.1 - 3.8e-28 98.3 0.3 8.2e-28 97.3 0.1 1.7 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 AAZ37532.1 - 6.8e-19 67.9 0.0 6.7e-09 35.0 0.0 3.2 3 0 0 3 3 3 3 tRNA synthetases class I (M) zf-FPG_IleRS PF06827.14 AAZ37532.1 - 1.8e-08 34.1 4.9 1.8e-08 34.1 4.9 2.0 2 0 0 2 2 2 1 Zinc finger found in FPG and IleRS tRNA-synt_1_2 PF13603.6 AAZ37532.1 - 4.2e-08 32.9 0.0 7.7e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 AAZ37532.1 - 1.6e-05 24.4 0.0 0.0022 17.4 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 AAZ37532.1 - 0.0086 15.0 0.0 0.031 13.2 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (K) BPD_transp_2 PF02653.16 AAZ37533.1 - 1.3e-27 96.7 46.0 1.3e-27 96.7 46.0 1.4 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component T3SS_HrpK1 PF16937.5 AAZ37534.1 - 2.5e-21 76.5 14.3 6.3e-21 75.2 6.3 4.0 3 1 0 3 3 3 1 Type III secretion system translocator protein, HrpF FdsD PF11390.8 AAZ37534.1 - 0.075 13.4 0.6 4.8 7.6 0.0 3.8 3 0 0 3 3 3 0 NADH-dependant formate dehydrogenase delta subunit FdsD Acetyltransf_CG PF14542.6 AAZ37535.1 - 8.2e-23 80.3 0.0 1e-22 80.0 0.0 1.1 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.7 AAZ37535.1 - 0.004 17.1 0.0 0.004 17.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAZ37535.1 - 0.011 15.9 0.0 0.013 15.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_15 PF17013.5 AAZ37535.1 - 0.14 11.6 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Putative acetyl-transferase AA_permease_2 PF13520.6 AAZ37536.1 - 6.4e-43 147.2 48.6 8.6e-43 146.7 48.6 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 AAZ37536.1 - 4.6e-34 117.8 43.0 6.1e-34 117.4 43.0 1.1 1 0 0 1 1 1 1 Amino acid permease Asn_synthase PF00733.21 AAZ37537.1 - 2.1e-83 280.9 0.1 2.6e-83 280.6 0.1 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 AAZ37537.1 - 5.4e-43 145.8 0.0 8.9e-43 145.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 AAZ37537.1 - 1.3e-39 135.4 0.0 1.3e-37 129.0 0.0 2.4 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 AAZ37537.1 - 0.021 14.3 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 Aluminium induced protein tRNA_Me_trans PF03054.16 AAZ37537.1 - 0.063 12.1 0.0 0.087 11.6 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase PfkB PF00294.24 AAZ37538.1 - 8.5e-46 156.6 0.9 1e-45 156.4 0.9 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 AAZ37538.1 - 0.0012 18.3 0.1 0.0018 17.7 0.1 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Peptidase_U40 PF10464.9 AAZ37538.1 - 0.016 14.9 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 Peptidase U40 DUF2170 PF09938.9 AAZ37539.1 - 3.9e-48 162.6 0.1 4.9e-48 162.3 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2170) DUF4132 PF13569.6 AAZ37539.1 - 0.18 11.6 0.1 0.43 10.4 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4132) MrpF_PhaF PF04066.13 AAZ37540.1 - 1.7e-17 63.5 9.1 1.7e-17 63.5 9.1 2.1 2 0 0 2 2 2 1 Multiple resistance and pH regulation protein F (MrpF / PhaF) TctA PF01970.16 AAZ37540.1 - 0.12 11.1 8.3 0.13 10.9 8.3 1.0 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family Fumarate_red_C PF02300.17 AAZ37540.1 - 0.19 11.8 2.4 0.22 11.6 2.4 1.1 1 0 0 1 1 1 0 Fumarate reductase subunit C DUF202 PF02656.15 AAZ37540.1 - 1.7 9.1 6.1 0.63 10.5 1.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF202) RNA_pol_Rpb1_1 PF04997.12 AAZ37541.1 - 2.5e-88 296.4 0.0 3.9e-88 295.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 AAZ37541.1 - 6.9e-79 265.0 0.0 1.3e-78 264.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 AAZ37541.1 - 7.1e-39 133.7 0.1 4.1e-28 98.7 0.0 3.0 2 1 1 3 3 3 2 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 AAZ37541.1 - 4.2e-31 108.0 0.2 2.3e-29 102.3 0.0 2.7 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 AAZ37541.1 - 3.8e-20 71.8 0.4 8e-20 70.8 0.4 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Peptidase_M23 PF01551.22 AAZ37541.1 - 0.0001 22.4 0.2 0.57 10.4 0.0 4.7 4 1 1 5 5 5 1 Peptidase family M23 Apocytochr_F_C PF01333.19 AAZ37541.1 - 0.0095 16.0 0.0 1 9.4 0.0 2.7 2 0 0 2 2 2 1 Apocytochrome F, C-terminal Biotin_lipoyl_2 PF13533.6 AAZ37541.1 - 0.039 13.8 0.9 42 4.1 0.1 3.7 3 0 0 3 3 3 0 Biotin-lipoyl like DUF3150 PF11348.8 AAZ37541.1 - 0.044 13.0 0.0 0.088 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) Biotin_lipoyl PF00364.22 AAZ37541.1 - 0.11 12.3 2.3 0.55 10.1 0.2 3.1 3 0 0 3 3 3 0 Biotin-requiring enzyme T2SSC PF11356.8 AAZ37542.1 - 9.8e-07 28.8 0.1 1.2e-06 28.5 0.1 1.1 1 0 0 1 1 1 1 Type II secretion system protein C HofP PF10748.9 AAZ37542.1 - 0.0014 18.2 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 DNA utilization proteins HofP PilP PF04351.13 AAZ37542.1 - 0.003 17.5 0.0 0.004 17.1 0.0 1.1 1 0 0 1 1 1 1 Pilus assembly protein, PilP CMD PF02627.20 AAZ37543.1 - 2.9e-17 62.5 1.9 1.4e-14 53.9 0.5 2.2 1 1 1 2 2 2 2 Carboxymuconolactone decarboxylase family PA26 PF04636.13 AAZ37543.1 - 0.00018 20.5 0.1 0.00023 20.2 0.1 1.1 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) HSP70 PF00012.20 AAZ37544.1 - 6.9e-260 863.4 19.2 7.9e-260 863.2 19.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 AAZ37544.1 - 1.7e-12 46.8 9.0 5.1e-11 42.0 1.3 3.0 3 1 0 3 3 3 2 MreB/Mbl protein Hydantoinase_A PF01968.18 AAZ37544.1 - 0.00018 20.9 1.6 0.0012 18.2 0.1 2.3 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase FGGY_C PF02782.16 AAZ37544.1 - 0.00037 20.3 0.0 0.00078 19.2 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 AAZ37544.1 - 0.084 13.3 8.0 1.6 9.2 0.4 3.7 3 2 0 3 3 3 0 Cell division protein FtsA Pep_deformylase PF01327.21 AAZ37545.1 - 1.2e-52 177.7 0.0 1.4e-52 177.5 0.0 1.0 1 0 0 1 1 1 1 Polypeptide deformylase CCD PF07860.11 AAZ37545.1 - 0.017 15.1 0.0 0.024 14.7 0.0 1.2 1 0 0 1 1 1 0 WisP family C-Terminal Region GGDEF PF00990.21 AAZ37546.1 - 3.1e-31 108.3 0.1 4.6e-31 107.8 0.1 1.2 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain GGDEF_2 PF17853.1 AAZ37546.1 - 0.0017 18.6 2.2 0.0067 16.7 1.1 2.0 1 1 1 2 2 2 1 GGDEF-like domain PP-binding PF00550.25 AAZ37548.1 - 1.2e-16 60.8 0.3 1.3e-16 60.7 0.3 1.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 AAZ37548.1 - 1.6e-06 28.2 1.2 2.3e-06 27.8 1.1 1.3 1 1 0 1 1 1 1 Acyl-carrier Ribosomal_L50 PF10501.9 AAZ37548.1 - 0.019 15.1 0.1 0.029 14.5 0.1 1.4 1 1 0 1 1 1 0 Ribosomal subunit 39S DUF1896 PF08989.10 AAZ37548.1 - 0.025 14.7 0.1 0.027 14.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1896) UPF0149 PF03695.13 AAZ37549.1 - 2.6e-30 106.0 2.6 2.9e-30 105.8 2.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0149) Haem_oxygenas_2 PF14518.6 AAZ37550.1 - 2.3e-12 47.0 2.9 3.2e-12 46.6 2.9 1.2 1 0 0 1 1 1 1 Iron-containing redox enzyme TENA_THI-4 PF03070.16 AAZ37550.1 - 2.9e-06 27.2 3.6 8.6e-06 25.7 3.6 1.7 1 1 0 1 1 1 1 TENA/THI-4/PQQC family DUF469 PF04320.14 AAZ37550.1 - 0.037 14.9 0.0 0.091 13.6 0.0 1.6 1 0 0 1 1 1 0 Protein with unknown function (DUF469) SMI1_KNR4 PF09346.10 AAZ37551.1 - 9.7e-05 22.8 0.3 0.00016 22.1 0.3 1.3 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Lip_A_acyltrans PF03279.13 AAZ37552.1 - 1.4e-45 155.8 0.0 1.7e-45 155.5 0.0 1.0 1 0 0 1 1 1 1 Bacterial lipid A biosynthesis acyltransferase Pyrophosphatase PF00719.19 AAZ37553.1 - 8.4e-55 184.9 0.0 9.5e-55 184.8 0.0 1.0 1 0 0 1 1 1 1 Inorganic pyrophosphatase YajC PF02699.15 AAZ37554.1 - 1.5e-27 95.3 0.3 1.7e-27 95.1 0.3 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit T2SSM PF04612.12 AAZ37554.1 - 0.07 13.2 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M DUF1654 PF07867.11 AAZ37555.1 - 6.3e-36 121.9 0.2 7.7e-36 121.7 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1654) CorA PF01544.18 AAZ37556.1 - 3.4e-51 174.3 1.3 4.5e-51 173.9 1.3 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DDE_Tnp_IS66 PF03050.14 AAZ37556.1 - 0.083 12.3 0.1 0.25 10.8 0.0 1.7 1 1 0 2 2 2 0 Transposase IS66 family ABC_tran PF00005.27 AAZ37557.1 - 4.2e-29 101.8 0.0 5.5e-29 101.4 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 AAZ37557.1 - 2.5e-06 28.0 0.1 4e-06 27.3 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AAZ37557.1 - 2.8e-05 24.1 0.1 4.3e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 AAZ37557.1 - 0.00012 21.6 0.0 0.00098 18.6 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AAZ37557.1 - 0.00086 19.2 0.1 0.82 9.4 0.0 2.3 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AAZ37557.1 - 0.0011 18.7 0.1 0.0022 17.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AAZ37557.1 - 0.0011 19.2 0.0 0.0022 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 AAZ37557.1 - 0.0024 17.7 0.0 0.17 11.6 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein Zeta_toxin PF06414.12 AAZ37557.1 - 0.023 14.0 0.0 0.045 13.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.23 AAZ37557.1 - 0.04 14.0 0.0 0.085 12.9 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Septin PF00735.18 AAZ37557.1 - 0.071 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Septin NACHT PF05729.12 AAZ37557.1 - 0.092 12.7 0.2 0.24 11.3 0.1 1.7 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 AAZ37557.1 - 0.1 12.3 0.1 0.38 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 AAZ37557.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 AAZ37557.1 - 0.11 12.6 0.3 0.23 11.6 0.3 1.8 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 AAZ37557.1 - 0.13 11.8 0.1 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.6 AAZ37557.1 - 0.16 12.2 0.0 2.2 8.6 0.0 2.3 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.6 AAZ37557.1 - 0.22 11.5 0.0 0.43 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Oxidored_q3 PF00499.20 AAZ37558.1 - 2.5e-32 111.6 17.7 2.9e-32 111.4 17.7 1.1 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 BPD_transp_1 PF00528.22 AAZ37559.1 - 3.8e-12 46.3 2.8 3.8e-12 46.3 2.8 1.9 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component SPC12 PF06645.13 AAZ37559.1 - 0.26 11.4 4.4 0.79 9.9 0.4 2.8 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) GCHY-1 PF02649.14 AAZ37560.1 - 1.8e-70 237.4 0.0 2e-70 237.2 0.0 1.0 1 0 0 1 1 1 1 Type I GTP cyclohydrolase folE2 PQQ_2 PF13360.6 AAZ37561.1 - 7.9e-54 182.7 14.5 2.6e-45 154.8 9.5 2.9 1 1 2 3 3 3 3 PQQ-like domain PQQ PF01011.21 AAZ37561.1 - 1.3e-28 97.5 3.6 7.5e-06 25.6 0.0 5.9 6 0 0 6 6 6 5 PQQ enzyme repeat PQQ_3 PF13570.6 AAZ37561.1 - 1.9e-24 85.4 24.1 1.5e-05 25.3 0.1 7.9 8 0 0 8 8 8 6 PQQ-like domain DraK_HK_N PF18092.1 AAZ37561.1 - 0.038 14.4 0.1 15 6.1 0.0 2.9 3 0 0 3 3 3 0 DraK Histidine Kinase N-terminal domain LexA_DNA_bind PF01726.16 AAZ37562.1 - 0.15 11.9 0.0 12 5.8 0.0 2.2 2 0 0 2 2 2 0 LexA DNA binding domain HTH_45 PF14947.6 AAZ37562.1 - 0.21 11.6 0.0 1.1 9.3 0.0 1.9 1 1 1 2 2 2 0 Winged helix-turn-helix PP-binding PF00550.25 AAZ37563.1 - 1.2e-08 35.2 0.4 1.3e-08 35.0 0.4 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site FAD_binding_2 PF00890.24 AAZ37564.1 - 7e-117 391.0 10.2 8.7e-117 390.7 10.2 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 AAZ37564.1 - 1.8e-40 137.9 0.1 2.9e-40 137.2 0.1 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 AAZ37564.1 - 2.2e-05 23.9 5.9 6.2e-05 22.4 2.3 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AAZ37564.1 - 0.00028 20.1 6.3 0.00098 18.3 3.0 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.24 AAZ37564.1 - 0.00095 18.8 6.5 0.021 14.4 6.3 2.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 AAZ37564.1 - 0.0054 15.5 1.5 0.0054 15.5 1.5 2.8 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_3 PF01494.19 AAZ37564.1 - 0.0097 15.2 0.7 0.019 14.2 0.7 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 AAZ37564.1 - 0.074 12.3 1.5 0.59 9.3 0.1 2.3 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.6 AAZ37564.1 - 0.13 11.5 0.3 0.28 10.4 0.3 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AAZ37564.1 - 4.7 6.4 9.3 0.54 9.6 3.9 2.2 3 0 0 3 3 3 0 FAD dependent oxidoreductase Kdo PF06293.14 AAZ37565.1 - 1.7e-16 60.2 0.1 2e-10 40.4 0.0 2.6 2 1 1 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 AAZ37565.1 - 3.9e-10 40.1 15.5 0.002 18.1 3.8 4.3 1 1 2 3 3 3 3 Phosphotransferase enzyme family RIO1 PF01163.22 AAZ37565.1 - 2e-05 24.3 0.0 0.0012 18.5 0.0 2.3 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.25 AAZ37565.1 - 0.0045 16.4 0.0 1.8 7.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain GlcNAc_2-epim PF07221.11 AAZ37566.1 - 7.9e-130 433.1 13.7 1.1e-129 432.6 13.7 1.2 1 0 0 1 1 1 1 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Glyco_hydro_76 PF03663.14 AAZ37566.1 - 6.4e-05 22.6 9.2 0.0051 16.4 1.1 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 76 Glyco_hydro_127 PF07944.12 AAZ37566.1 - 0.018 13.6 0.5 0.24 9.8 0.0 2.0 2 0 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 LANC_like PF05147.13 AAZ37566.1 - 0.16 10.5 0.1 16 3.9 0.1 2.5 2 0 0 2 2 2 0 Lanthionine synthetase C-like protein HopJ PF08888.11 AAZ37567.1 - 6.3e-36 122.9 0.0 7.1e-36 122.8 0.0 1.0 1 0 0 1 1 1 1 HopJ type III effector protein BacA PF02673.18 AAZ37568.1 - 3.4e-85 285.8 15.2 3.9e-85 285.6 15.2 1.0 1 0 0 1 1 1 1 Bacitracin resistance protein BacA HTH_27 PF13463.6 AAZ37569.1 - 3.1e-08 34.0 0.0 5.4e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR PF01047.22 AAZ37569.1 - 4.8e-07 29.6 0.0 7.2e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 AAZ37569.1 - 6.5e-06 25.9 1.7 3.7e-05 23.5 0.1 2.5 3 0 0 3 3 3 1 MarR family RP-C PF03428.13 AAZ37569.1 - 0.00032 20.4 0.0 0.00059 19.5 0.0 1.5 1 0 0 1 1 1 1 Replication protein C N-terminal domain HTH_IclR PF09339.10 AAZ37569.1 - 0.003 17.3 0.3 0.084 12.7 0.0 2.4 2 0 0 2 2 2 1 IclR helix-turn-helix domain HxlR PF01638.17 AAZ37569.1 - 0.046 13.6 0.0 0.078 12.8 0.0 1.4 1 0 0 1 1 1 0 HxlR-like helix-turn-helix RPA_C PF08784.11 AAZ37569.1 - 0.12 13.0 0.0 0.3 11.8 0.0 1.6 2 0 0 2 2 2 0 Replication protein A C terminal F-box-like PF12937.7 AAZ37569.1 - 0.13 12.2 1.6 1.5 8.8 0.1 2.3 2 0 0 2 2 2 0 F-box-like HTH_45 PF14947.6 AAZ37569.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix EI24 PF07264.11 AAZ37570.1 - 0.03 14.6 3.7 0.031 14.5 3.7 1.0 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) MmlI PF09448.10 AAZ37571.1 - 5e-06 26.9 0.0 1.6e-05 25.3 0.0 1.7 2 0 0 2 2 2 1 Methylmuconolactone methyl-isomerase EthD PF07110.11 AAZ37571.1 - 0.0037 18.4 0.3 0.018 16.2 0.0 2.2 2 1 0 2 2 2 1 EthD domain CSN8_PSD8_EIF3K PF10075.9 AAZ37571.1 - 0.026 14.5 0.1 0.1 12.6 0.1 1.9 1 1 0 1 1 1 0 CSN8/PSMD8/EIF3K family Trm112p PF03966.16 AAZ37572.1 - 2.4e-10 40.8 0.1 5.3e-10 39.7 0.1 1.6 1 1 0 1 1 1 1 Trm112p-like protein RecX PF02631.16 AAZ37574.1 - 4.9e-34 117.4 0.1 8.2e-32 110.2 0.1 1.5 1 1 1 2 2 2 2 RecX family SelB-wing_2 PF09106.11 AAZ37574.1 - 0.004 17.3 0.7 0.0088 16.2 0.1 1.8 2 0 0 2 2 2 1 Elongation factor SelB, winged helix DUF494 PF04361.13 AAZ37574.1 - 0.017 15.0 0.1 3.2 7.6 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF494) DUF1456 PF07308.13 AAZ37575.1 - 6.7e-55 183.3 0.2 1.3e-26 92.7 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF1456) TonB_dep_Rec PF00593.24 AAZ37576.1 - 7.3e-53 181.1 27.8 7.3e-53 181.1 27.8 1.7 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 AAZ37576.1 - 3e-16 59.9 0.4 8.7e-16 58.4 0.4 1.9 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain STN PF07660.14 AAZ37576.1 - 2.3e-08 33.7 0.0 5e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Secretin and TonB N terminus short domain PD40 PF07676.12 AAZ37577.1 - 3.8e-41 138.2 3.6 3.1e-12 46.1 0.0 6.1 6 0 0 6 6 6 4 WD40-like Beta Propeller Repeat TolB_N PF04052.13 AAZ37577.1 - 4.1e-31 107.3 0.0 9.1e-31 106.2 0.0 1.6 1 0 0 1 1 1 1 TolB amino-terminal domain DPPIV_N PF00930.21 AAZ37577.1 - 6.8e-09 34.9 0.0 0.00043 19.1 0.0 3.6 1 1 2 3 3 3 3 Dipeptidyl peptidase IV (DPP IV) N-terminal region Gmad1 PF10647.9 AAZ37577.1 - 2.2e-05 24.4 0.0 1.8 8.2 0.0 3.4 1 1 2 3 3 3 3 Lipoprotein LpqB beta-propeller domain Pectate_lyase22 PF14583.6 AAZ37577.1 - 0.0031 16.2 0.0 0.23 10.1 0.0 3.0 2 1 1 3 3 3 2 Oligogalacturonate lyase DUF5050 PF16472.5 AAZ37577.1 - 0.01 15.1 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5050) ZFYVE21_C PF16696.5 AAZ37577.1 - 0.076 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Zinc finger FYVE domain-containing protein 21 C-terminus SGL PF08450.12 AAZ37577.1 - 0.14 11.7 0.1 12 5.4 0.0 3.0 1 1 2 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region FAD_binding_5 PF00941.21 AAZ37578.1 - 3.2e-44 150.7 0.0 4.5e-44 150.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 AAZ37578.1 - 2.8e-15 56.3 0.5 6e-15 55.3 0.1 1.8 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fapy_DNA_glyco PF01149.24 AAZ37579.1 - 2.5e-33 115.2 0.0 4.6e-33 114.3 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 AAZ37579.1 - 1.2e-23 82.9 0.0 1.8e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain zf-FPG_IleRS PF06827.14 AAZ37579.1 - 9.4e-10 38.2 3.7 1.8e-09 37.3 3.7 1.5 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS Auto_anti-p27 PF06677.12 AAZ37579.1 - 0.12 12.6 2.0 0.2 11.8 2.0 1.3 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) MCPsignal PF00015.21 AAZ37580.1 - 5.6e-45 153.2 37.3 6.3e-44 149.8 23.7 2.8 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain dCache_1 PF02743.18 AAZ37580.1 - 9.3e-35 120.6 0.1 9.3e-35 120.6 0.1 3.2 2 1 1 3 3 3 1 Cache domain HAMP PF00672.25 AAZ37580.1 - 3.1e-17 62.7 2.1 1.6e-15 57.2 0.2 3.9 2 1 1 3 3 3 1 HAMP domain dCache_2 PF08269.11 AAZ37580.1 - 0.00022 20.5 0.0 0.00022 20.5 0.0 3.2 4 0 0 4 4 4 1 Cache domain sCache_2 PF17200.4 AAZ37580.1 - 0.0017 18.2 0.0 0.0017 18.2 0.0 3.3 5 1 0 5 5 5 1 Single Cache domain 2 Arfaptin PF06456.13 AAZ37580.1 - 0.0065 16.1 5.3 0.019 14.5 0.4 2.6 1 1 1 2 2 2 1 Arfaptin-like domain BLOC1_2 PF10046.9 AAZ37580.1 - 0.02 15.2 18.4 0.15 12.4 0.2 4.7 5 1 0 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phage_DsbA PF11126.8 AAZ37580.1 - 0.067 13.4 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator DsbA DUF4381 PF14316.6 AAZ37580.1 - 0.1 12.9 3.5 1.3 9.3 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) FANCI_S2 PF14676.6 AAZ37580.1 - 0.12 12.6 5.0 0.19 12.0 2.9 2.5 2 1 0 2 2 2 0 FANCI solenoid 2 ESX-1_EspG PF14011.6 AAZ37580.1 - 0.22 11.1 12.3 0.59 9.7 0.0 3.4 3 0 0 3 3 3 0 EspG family GARP PF16731.5 AAZ37580.1 - 0.24 11.1 20.6 0.54 9.9 1.5 2.5 2 1 0 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma tRNA_bind_2 PF13725.6 AAZ37580.1 - 0.29 10.8 4.8 2 8.0 0.9 2.5 2 0 0 2 2 2 0 Possible tRNA binding domain Baculo_11_kDa PF06143.11 AAZ37580.1 - 0.54 9.9 4.2 6 6.5 1.7 2.9 2 0 0 2 2 2 0 Baculovirus 11 kDa family DUF3382 PF11862.8 AAZ37580.1 - 1.8 8.9 5.8 0.73 10.1 0.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3382) DUF948 PF06103.11 AAZ37580.1 - 6.3 7.1 36.6 10 6.5 0.4 6.4 2 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) CCDC144C PF14915.6 AAZ37581.1 - 5.7e-05 22.4 17.2 0.0052 16.0 4.8 3.0 1 1 2 3 3 3 2 CCDC144C protein coiled-coil region MAP65_ASE1 PF03999.12 AAZ37581.1 - 0.0006 18.7 8.3 0.00071 18.4 8.3 1.1 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) DUF1664 PF07889.12 AAZ37581.1 - 0.0027 17.7 10.8 0.04 14.0 3.6 3.5 2 1 2 4 4 4 2 Protein of unknown function (DUF1664) Fez1 PF06818.15 AAZ37581.1 - 0.004 17.6 19.7 0.027 14.9 19.7 2.3 1 1 0 1 1 1 1 Fez1 CENP-F_leu_zip PF10473.9 AAZ37581.1 - 0.0047 17.0 20.3 0.22 11.5 9.2 3.2 1 1 2 3 3 3 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlxA PF14282.6 AAZ37581.1 - 0.0059 16.6 10.7 0.0059 16.6 10.7 3.6 1 1 2 3 3 2 2 FlxA-like protein Tropomyosin_1 PF12718.7 AAZ37581.1 - 0.011 15.9 1.3 0.011 15.9 1.3 3.2 1 1 2 3 3 3 0 Tropomyosin like Fib_alpha PF08702.10 AAZ37581.1 - 0.011 15.9 11.0 0.024 14.8 3.4 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ERM PF00769.19 AAZ37581.1 - 0.012 15.4 21.7 0.017 14.9 21.7 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family CREPT PF16566.5 AAZ37581.1 - 0.015 15.4 10.9 0.027 14.6 5.6 2.3 2 1 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Phage_GP20 PF06810.11 AAZ37581.1 - 0.018 14.9 18.2 0.093 12.5 7.0 2.5 1 1 1 2 2 2 0 Phage minor structural protein GP20 Lectin_N PF03954.14 AAZ37581.1 - 0.025 14.3 19.1 0.096 12.4 1.2 3.4 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain CALCOCO1 PF07888.11 AAZ37581.1 - 0.044 12.7 20.1 0.1 11.4 20.0 1.6 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like PI3K_P85_iSH2 PF16454.5 AAZ37581.1 - 0.07 12.7 16.0 0.96 9.0 11.7 3.6 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain HOOK PF05622.12 AAZ37581.1 - 0.086 11.0 19.4 0.38 8.8 17.6 1.9 1 1 1 2 2 2 0 HOOK protein Cas_Csa4 PF09703.10 AAZ37581.1 - 0.1 11.9 1.6 0.16 11.3 1.0 1.5 1 1 0 1 1 1 0 CRISPR-associated protein (Cas_Csa4) UPF0242 PF06785.11 AAZ37581.1 - 0.13 12.4 13.7 0.094 12.8 7.1 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Nup54 PF13874.6 AAZ37581.1 - 0.15 12.2 18.5 1.6 8.8 10.5 2.9 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Occludin_ELL PF07303.13 AAZ37581.1 - 0.21 12.3 5.8 0.35 11.6 0.4 3.0 2 1 2 4 4 4 0 Occludin homology domain Atg14 PF10186.9 AAZ37581.1 - 0.21 10.6 16.4 0.22 10.5 10.6 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 SHE3 PF17078.5 AAZ37581.1 - 0.22 11.2 12.3 0.13 12.0 6.3 2.6 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 DUF4200 PF13863.6 AAZ37581.1 - 0.23 11.9 19.7 0.76 10.2 11.0 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) HlyD_2 PF12700.7 AAZ37581.1 - 0.25 10.1 3.6 0.24 10.1 0.9 2.0 1 1 1 2 2 2 0 HlyD family secretion protein APG6_N PF17675.1 AAZ37581.1 - 0.38 11.3 25.3 0.33 11.5 13.7 3.1 1 1 2 3 3 3 0 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 AAZ37581.1 - 0.71 10.1 20.5 0.43 10.8 5.5 3.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Baculo_PEP_C PF04513.12 AAZ37581.1 - 0.79 9.8 20.0 4.8 7.2 8.4 3.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus LemA PF04011.12 AAZ37581.1 - 0.85 9.5 9.8 0.069 13.0 3.4 2.2 2 1 0 2 2 1 0 LemA family ADIP PF11559.8 AAZ37581.1 - 0.87 9.7 21.6 0.46 10.6 9.1 3.2 1 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding AAA_13 PF13166.6 AAZ37581.1 - 1.3 7.6 16.6 4.8 5.7 9.8 2.0 1 1 1 2 2 2 0 AAA domain DUF724 PF05266.14 AAZ37581.1 - 1.3 8.8 14.3 5.7 6.7 0.9 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF724) Fungal_TACC PF12709.7 AAZ37581.1 - 1.5 9.4 11.5 0.55 10.7 0.4 4.0 4 1 0 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF812 PF05667.11 AAZ37581.1 - 1.7 7.4 18.0 2.5 6.9 18.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Med10 PF09748.9 AAZ37581.1 - 1.8 8.5 8.7 1.5 8.8 0.3 3.2 2 2 1 3 3 3 0 Transcription factor subunit Med10 of Mediator complex FUSC PF04632.12 AAZ37581.1 - 1.9 6.9 14.9 2.5 6.5 14.9 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family COG2 PF06148.11 AAZ37581.1 - 2.3 8.3 14.9 3.2 7.8 0.6 3.5 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DivIC PF04977.15 AAZ37581.1 - 2.7 7.8 27.3 4.6 7.1 0.0 5.3 3 1 3 6 6 6 0 Septum formation initiator YabA PF06156.13 AAZ37581.1 - 2.7 8.7 15.4 0.7 10.6 3.1 3.6 1 1 2 3 3 3 0 Initiation control protein YabA Jnk-SapK_ap_N PF09744.9 AAZ37581.1 - 2.7 8.2 18.8 4.2 7.6 10.9 2.3 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 FlaC_arch PF05377.11 AAZ37581.1 - 3.4 8.1 7.0 54 4.3 0.3 4.2 2 1 0 3 3 3 0 Flagella accessory protein C (FlaC) SLX9 PF15341.6 AAZ37581.1 - 4 7.9 12.9 0.86 10.0 7.6 2.2 1 1 1 2 2 2 0 Ribosome biogenesis protein SLX9 Rx_N PF18052.1 AAZ37581.1 - 5.4 7.4 8.0 5.5 7.3 1.7 2.7 1 1 1 2 2 2 0 Rx N-terminal domain Tup_N PF08581.10 AAZ37581.1 - 6.4 7.2 9.1 2.2 8.7 0.7 3.3 1 1 3 4 4 3 0 Tup N-terminal DUF2203 PF09969.9 AAZ37581.1 - 7.2 7.4 12.5 11 6.7 5.9 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF3347 PF11827.8 AAZ37581.1 - 7.4 6.7 10.6 5.6 7.1 8.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3347) DUF3450 PF11932.8 AAZ37581.1 - 8.5 5.6 25.3 2.8 7.2 13.8 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Fmp27_WPPW PF10359.9 AAZ37581.1 - 8.8 5.0 11.3 7.6 5.3 9.3 1.7 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain PepSY_TM PF03929.16 AAZ37581.1 - 9.9 5.7 7.4 6.5 6.3 4.9 1.8 1 1 1 2 2 2 0 PepSY-associated TM region Cupin_2 PF07883.11 AAZ37582.1 - 2.2e-18 65.7 0.0 3.6e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Cupin domain HTH_3 PF01381.22 AAZ37582.1 - 1.6e-13 50.5 0.1 2.7e-13 49.8 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 AAZ37582.1 - 2.2e-11 43.6 0.2 4.8e-11 42.5 0.2 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 AAZ37582.1 - 4.4e-09 36.6 0.0 7.1e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 AAZ37582.1 - 0.00065 19.2 0.1 0.0014 18.1 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_37 PF13744.6 AAZ37582.1 - 0.00083 19.3 0.0 0.0018 18.2 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.6 AAZ37582.1 - 0.0034 17.1 0.2 0.0064 16.2 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AAZ37582.1 - 0.013 15.2 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain HTH_24 PF13412.6 AAZ37582.1 - 0.019 14.5 0.1 0.042 13.4 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR PF01047.22 AAZ37582.1 - 0.021 14.7 0.1 0.038 13.9 0.1 1.4 1 0 0 1 1 1 0 MarR family HTH_26 PF13443.6 AAZ37582.1 - 0.026 14.9 0.2 0.043 14.2 0.2 1.3 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain CENP-B_N PF04218.13 AAZ37582.1 - 0.028 14.1 0.1 0.043 13.5 0.1 1.3 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_psq PF05225.16 AAZ37582.1 - 0.049 13.4 0.1 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 helix-turn-helix, Psq domain HTH_25 PF13413.6 AAZ37582.1 - 0.052 13.4 0.0 0.098 12.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain LacI PF00356.21 AAZ37582.1 - 0.055 13.3 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family MannoseP_isomer PF01050.18 AAZ37582.1 - 0.062 13.2 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase Phage_CI_repr PF07022.13 AAZ37582.1 - 0.074 13.2 0.0 0.087 12.9 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain Cupin_3 PF05899.12 AAZ37582.1 - 0.097 12.4 0.3 0.85 9.4 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF861) YdaS_antitoxin PF15943.5 AAZ37582.1 - 0.13 12.2 0.0 0.33 10.9 0.0 1.7 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Isochorismatase PF00857.20 AAZ37583.1 - 7.4e-28 97.9 0.0 8.5e-28 97.7 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family ABC_tran PF00005.27 AAZ37584.1 - 1.4e-31 109.9 0.0 1.8e-31 109.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAZ37584.1 - 5e-10 39.7 0.0 0.00037 20.4 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AAZ37584.1 - 0.0011 18.7 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AAZ37584.1 - 0.0025 17.5 0.1 0.0045 16.7 0.1 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AAZ37584.1 - 0.0029 18.0 0.0 0.0044 17.4 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AAZ37584.1 - 0.0039 17.1 0.1 0.0066 16.4 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 AAZ37584.1 - 0.0054 17.2 0.0 0.0081 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 AAZ37584.1 - 0.0096 15.8 0.1 0.02 14.8 0.1 1.5 1 0 0 1 1 1 1 NACHT domain AAA_5 PF07728.14 AAZ37584.1 - 0.039 14.0 0.1 0.073 13.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF3584 PF12128.8 AAZ37584.1 - 0.041 11.4 0.2 0.055 11.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_22 PF13401.6 AAZ37584.1 - 0.044 14.1 0.4 0.21 11.9 0.4 2.0 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 AAZ37584.1 - 0.049 13.0 0.0 0.1 11.9 0.0 1.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.23 AAZ37584.1 - 0.061 13.4 0.1 0.078 13.1 0.1 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_30 PF13604.6 AAZ37584.1 - 0.081 12.6 0.2 0.24 11.1 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 AAZ37584.1 - 0.23 10.0 0.0 0.29 9.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain DUF3751 PF12571.8 AAZ37585.1 - 1.9e-37 128.7 1.0 3.8e-37 127.7 0.2 1.9 2 0 0 2 2 2 1 Phage tail-collar fibre protein TonB_dep_Rec PF00593.24 AAZ37586.1 - 1.2e-45 157.3 45.5 1.2e-45 157.3 45.5 2.1 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 AAZ37586.1 - 4.6e-10 40.0 1.7 8.2e-10 39.2 0.7 2.0 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain Phage_Coat_A PF05357.13 AAZ37586.1 - 0.019 14.8 0.2 0.074 12.9 0.2 2.1 1 0 0 1 1 1 0 Phage Coat Protein A DUF2076 PF09849.9 AAZ37587.1 - 2.1e-63 214.8 18.0 2.5e-63 214.5 18.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) DUF641 PF04859.12 AAZ37587.1 - 8.7e-05 22.9 0.9 0.00013 22.3 0.9 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) SlyX PF04102.12 AAZ37587.1 - 0.00047 20.7 3.2 0.00047 20.7 3.2 1.8 2 0 0 2 2 2 1 SlyX ERM PF00769.19 AAZ37587.1 - 0.0025 17.7 2.5 0.0034 17.3 2.5 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family DUF16 PF01519.16 AAZ37587.1 - 0.0044 17.5 0.2 0.007 16.8 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF16 Csm1_N PF18504.1 AAZ37587.1 - 0.0083 16.4 2.1 0.015 15.6 2.1 1.3 1 0 0 1 1 1 1 Csm1 N-terminal domain TMF_DNA_bd PF12329.8 AAZ37587.1 - 0.016 15.2 1.8 0.032 14.2 1.8 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding YlqD PF11068.8 AAZ37587.1 - 0.017 15.5 2.7 0.026 14.9 2.7 1.3 1 0 0 1 1 1 0 YlqD protein Phage_GPO PF05929.11 AAZ37587.1 - 0.079 12.6 2.1 0.12 11.9 2.1 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DivIC PF04977.15 AAZ37587.1 - 1 9.1 5.8 2.2 8.1 5.8 1.5 1 0 0 1 1 1 0 Septum formation initiator LPP PF04728.13 AAZ37587.1 - 1.1 9.7 7.9 0.37 11.2 4.6 1.9 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DUF3382 PF11862.8 AAZ37588.1 - 0.00099 19.3 0.3 0.0011 19.2 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3382) SLATT_5 PF18160.1 AAZ37588.1 - 0.14 11.5 1.6 0.17 11.2 1.6 1.1 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Aminotran_3 PF00202.21 AAZ37590.1 - 1.7e-91 306.9 0.0 2e-91 306.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III GST_N_3 PF13417.6 AAZ37591.1 - 6.1e-13 49.0 0.0 9.3e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 AAZ37591.1 - 9.7e-11 41.7 0.0 1.8e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_N_2 PF13409.6 AAZ37591.1 - 1.9e-07 31.2 0.0 2.7e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 AAZ37591.1 - 0.00089 19.6 0.0 0.0012 19.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GATase_3 PF07685.14 AAZ37592.1 - 6e-58 195.7 0.0 8.5e-58 195.2 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain CbiA PF01656.23 AAZ37592.1 - 1.9e-22 79.6 0.0 3.5e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.6 AAZ37592.1 - 4.9e-20 72.2 0.0 7.7e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain MobB PF03205.14 AAZ37592.1 - 0.05 13.5 0.0 0.12 12.3 0.0 1.5 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B CLP1_P PF16575.5 AAZ37592.1 - 0.11 12.2 0.0 0.29 10.9 0.0 1.6 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop RsmJ PF04378.13 AAZ37593.1 - 1.1e-92 309.7 0.0 1.4e-92 309.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA large subunit methyltransferase D, RlmJ Cons_hypoth95 PF03602.15 AAZ37593.1 - 0.13 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 AstE_AspA PF04952.14 AAZ37594.1 - 2.1e-25 89.4 0.0 5.6e-24 84.7 0.0 2.1 1 1 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Peptidase_M14 PF00246.24 AAZ37594.1 - 0.18 11.6 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Zinc carboxypeptidase Radical_SAM PF04055.21 AAZ37595.1 - 5.2e-29 101.8 0.0 2.9e-28 99.3 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily TRAM_2 PF18693.1 AAZ37595.1 - 2.4e-21 75.6 0.6 5.5e-21 74.5 0.6 1.6 1 0 0 1 1 1 1 TRAM domain UPF0004 PF00919.20 AAZ37595.1 - 9.3e-21 73.7 0.2 2e-20 72.6 0.2 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 CLP1_P PF16575.5 AAZ37595.1 - 0.037 13.8 0.1 0.06 13.1 0.1 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Choline_kinase PF01633.20 AAZ37596.1 - 1.1e-12 48.0 0.1 1.6e-12 47.5 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 AAZ37596.1 - 0.00061 19.8 0.1 0.00078 19.4 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Dak1 PF02733.17 AAZ37597.1 - 6.6e-111 370.1 0.1 8.3e-111 369.8 0.1 1.0 1 0 0 1 1 1 1 Dak1 domain DUF1375 PF07119.12 AAZ37598.1 - 2.3e-15 56.7 0.7 3.5e-15 56.1 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1375) Transposase_mut PF00872.18 AAZ37599.1 - 1.5e-117 392.7 0.0 1.9e-117 392.3 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ37599.1 - 7.7e-05 23.0 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain DUF4844 PF16133.5 AAZ37599.1 - 0.23 12.0 0.0 0.55 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) ECH_1 PF00378.20 AAZ37600.1 - 8.2e-81 271.0 0.2 9.1e-81 270.9 0.2 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AAZ37600.1 - 8.7e-41 140.5 0.4 5.6e-37 128.0 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase PAPS_reduct PF01507.19 AAZ37601.1 - 3.1e-46 157.6 0.0 3.7e-46 157.3 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family HHH_9 PF17674.1 AAZ37601.1 - 0.017 16.0 0.0 0.043 14.7 0.0 1.6 1 0 0 1 1 1 0 HHH domain Cytochrom_D1 PF02239.16 AAZ37601.1 - 0.12 10.8 0.0 0.18 10.3 0.0 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain DUF4197 PF13852.6 AAZ37602.1 - 2.8e-73 245.9 7.3 3.2e-73 245.7 7.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4197) Phage_T7_Capsid PF05396.11 AAZ37602.1 - 0.064 13.6 2.5 0.098 13.0 1.0 2.1 2 1 1 3 3 3 0 Phage T7 capsid assembly protein PTAC PF06130.12 AAZ37602.1 - 0.088 13.0 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphate propanoyltransferase GAF PF01590.26 AAZ37603.1 - 2.2e-07 31.6 0.0 2.7e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 AAZ37603.1 - 2.1e-06 28.1 0.0 2.4e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 AAZ37603.1 - 0.05 14.0 0.0 0.079 13.3 0.0 1.3 1 0 0 1 1 1 0 GAF domain Fe-S_biosyn PF01521.20 AAZ37604.1 - 2.9e-20 72.5 0.0 3.3e-20 72.4 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis HTH_Tnp_1 PF01527.20 AAZ37605.1 - 3.8e-08 33.5 3.0 1.6e-07 31.5 3.0 1.8 1 1 0 1 1 1 1 Transposase TSC22 PF01166.18 AAZ37605.1 - 0.097 13.0 0.9 0.2 12.0 0.4 1.7 2 1 0 2 2 2 0 TSC-22/dip/bun family LysR_substrate PF03466.20 AAZ37606.1 - 8.8e-28 97.1 2.4 8.8e-28 97.1 2.4 1.4 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ37606.1 - 4.2e-22 77.9 2.8 8.7e-22 76.8 2.8 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_20 PF12840.7 AAZ37606.1 - 0.00096 19.2 0.6 0.0034 17.4 0.1 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_5 PF01022.20 AAZ37606.1 - 0.0021 17.9 0.1 0.0041 16.9 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_IclR PF09339.10 AAZ37606.1 - 0.0028 17.4 0.8 0.0028 17.4 0.8 2.1 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_24 PF13412.6 AAZ37606.1 - 0.0028 17.2 0.0 0.0077 15.8 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 AAZ37606.1 - 0.011 15.6 0.6 0.059 13.3 0.1 2.3 2 0 0 2 2 2 0 MarR family MarR PF01047.22 AAZ37606.1 - 0.025 14.5 0.4 0.25 11.3 0.1 2.2 2 0 0 2 2 2 0 MarR family HTH_11 PF08279.12 AAZ37606.1 - 0.089 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 HTH domain HTH_50 PF18024.1 AAZ37606.1 - 0.18 11.5 0.3 0.39 10.4 0.3 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Mur_ligase_M PF08245.12 AAZ37607.1 - 6.6e-12 45.8 0.0 1.2e-11 45.0 0.0 1.4 1 0 0 1 1 1 1 Mur ligase middle domain YjeF_N PF03853.15 AAZ37607.1 - 0.055 13.4 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus Na_H_Exchanger PF00999.21 AAZ37608.1 - 1.6e-64 218.1 48.1 1.6e-64 218.1 48.1 2.1 2 0 0 2 2 2 1 Sodium/hydrogen exchanger family DUF3464 PF11947.8 AAZ37608.1 - 0.24 11.2 1.8 0.31 10.8 0.0 2.2 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 Trp_oprn_chp PF09534.10 AAZ37608.1 - 3.6 7.3 8.1 37 4.1 5.7 3.3 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF3094 PF11293.8 AAZ37608.1 - 6.4 6.6 8.2 8.2 6.2 2.6 3.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) Peptidase_S9 PF00326.21 AAZ37609.1 - 8.5e-44 149.6 0.1 1.2e-43 149.1 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 AAZ37609.1 - 3.5e-07 30.0 0.3 8e-07 28.8 0.4 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 AAZ37609.1 - 5.4e-06 25.8 1.6 0.006 15.9 0.1 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 AAZ37609.1 - 0.00011 21.9 0.7 0.088 12.4 0.0 2.6 2 1 1 3 3 3 2 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.13 AAZ37609.1 - 0.002 17.8 0.0 0.0038 16.9 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 AAZ37609.1 - 0.045 13.6 1.1 0.28 11.0 1.1 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF2554 PF10829.8 AAZ37609.1 - 0.15 12.5 0.0 0.38 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2554) AXE1 PF05448.12 AAZ37609.1 - 0.29 9.8 0.6 10 4.7 0.4 2.7 2 1 0 2 2 2 0 Acetyl xylan esterase (AXE1) GcpE PF04551.14 AAZ37610.1 - 7.4e-136 452.8 0.0 8.5e-136 452.6 0.0 1.0 1 0 0 1 1 1 1 GcpE protein Peripla_BP_4 PF13407.6 AAZ37610.1 - 0.055 13.0 1.4 0.56 9.7 0.6 2.1 2 0 0 2 2 2 0 Periplasmic binding protein domain Sigma70_r4_2 PF08281.12 AAZ37611.1 - 8.4e-18 63.8 2.0 5e-16 58.1 0.2 2.5 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 AAZ37611.1 - 1.2e-11 44.2 0.6 2.3e-11 43.3 0.6 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 AAZ37611.1 - 1.1e-06 28.1 0.9 2e-06 27.2 0.1 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 AAZ37611.1 - 1.9e-06 27.9 0.4 3e-06 27.2 0.4 1.6 1 1 0 1 1 1 1 ECF sigma factor HTH_23 PF13384.6 AAZ37611.1 - 5.8e-06 25.9 0.2 2.1e-05 24.1 0.2 2.1 1 1 0 1 1 1 1 Homeodomain-like domain GerE PF00196.19 AAZ37611.1 - 4.2e-05 23.0 0.0 0.0001 21.8 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_11 PF08279.12 AAZ37611.1 - 0.0006 19.7 0.0 0.0017 18.2 0.0 1.7 1 0 0 1 1 1 1 HTH domain DUF2285 PF10074.9 AAZ37611.1 - 0.0018 18.9 4.2 0.0058 17.3 0.4 3.0 1 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2285) HTH_38 PF13936.6 AAZ37611.1 - 0.0021 17.8 0.0 0.0043 16.8 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 AAZ37611.1 - 0.0037 16.8 0.0 0.0092 15.5 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_29 PF13551.6 AAZ37611.1 - 0.0045 17.0 0.1 0.012 15.6 0.1 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 AAZ37611.1 - 0.0088 16.1 0.1 0.0088 16.1 0.1 1.9 2 0 0 2 2 1 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 AAZ37611.1 - 0.0092 15.4 0.0 0.026 13.9 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_7 PF02796.15 AAZ37611.1 - 0.015 15.4 0.0 0.13 12.4 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_AsnC-type PF13404.6 AAZ37611.1 - 0.022 14.6 0.0 0.074 12.9 0.0 1.9 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain TnsD PF15978.5 AAZ37611.1 - 0.037 13.0 0.3 0.32 9.9 0.0 2.1 2 0 0 2 2 2 0 Tn7-like transposition protein D PSD3 PF07626.11 AAZ37611.1 - 0.054 14.0 0.0 0.24 11.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1587) CHDCT2 PF08074.11 AAZ37611.1 - 0.061 13.5 0.1 0.083 13.1 0.1 1.3 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain HTH_40 PF14493.6 AAZ37611.1 - 0.073 13.5 0.0 0.19 12.2 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Phage_terminase PF10668.9 AAZ37611.1 - 0.087 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Phage terminase small subunit HTH_Mga PF08280.11 AAZ37611.1 - 0.09 12.8 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain DUF1804 PF08822.11 AAZ37611.1 - 0.097 12.6 0.6 0.35 10.8 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1804) CHASE3 PF05227.13 AAZ37611.1 - 0.099 12.6 1.7 0.21 11.5 1.7 1.7 1 1 0 1 1 1 0 CHASE3 domain Sigma70_r3 PF04539.16 AAZ37611.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-70 region 3 HTH_31 PF13560.6 AAZ37611.1 - 0.93 9.9 6.3 0.55 10.6 1.7 3.0 2 2 0 2 2 2 0 Helix-turn-helix domain SSF PF00474.17 AAZ37612.1 - 2.3e-24 86.0 40.5 5.9e-24 84.7 40.5 1.7 1 1 0 1 1 1 1 Sodium:solute symporter family SIS PF01380.22 AAZ37613.1 - 1.9e-31 108.7 0.6 4e-31 107.6 0.6 1.5 1 0 0 1 1 1 1 SIS domain CBS PF00571.28 AAZ37613.1 - 2.5e-15 56.7 2.0 1.5e-06 28.6 0.0 3.8 3 0 0 3 3 3 3 CBS domain SIS_2 PF13580.6 AAZ37613.1 - 0.0012 18.9 2.3 0.081 12.9 0.0 2.9 2 1 1 3 3 3 2 SIS domain DUF1127 PF06568.11 AAZ37614.1 - 1.7e-08 34.0 7.2 3.1e-08 33.2 7.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1127) CorA PF01544.18 AAZ37615.1 - 1.4e-54 185.5 0.0 1.5e-54 185.3 0.0 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Acetyltransf_10 PF13673.7 AAZ37616.1 - 1.6e-14 53.9 0.0 1.8e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAZ37616.1 - 2.8e-11 43.7 0.0 3.6e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAZ37616.1 - 5.1e-10 39.6 0.0 6.1e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 AAZ37616.1 - 0.08 13.1 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FR47 PF08445.10 AAZ37616.1 - 0.098 12.6 0.0 0.17 11.9 0.0 1.5 1 1 0 1 1 1 0 FR47-like protein Ribosomal_L17 PF01196.19 AAZ37617.1 - 3.3e-33 114.4 0.0 3.9e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L17 SBF PF01758.16 AAZ37618.1 - 1.7e-41 142.1 18.7 2.6e-41 141.4 18.7 1.3 1 0 0 1 1 1 1 Sodium Bile acid symporter family SBF_like PF13593.6 AAZ37618.1 - 3.2e-21 76.0 28.2 3.6e-21 75.8 28.2 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Mem_trans PF03547.18 AAZ37618.1 - 0.002 16.6 4.8 0.002 16.6 4.8 2.5 2 1 0 2 2 2 2 Membrane transport protein MFS_1 PF07690.16 AAZ37619.1 - 9.9e-49 166.1 41.7 9.9e-49 166.1 41.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 AAZ37619.1 - 1.1e-05 24.9 29.1 0.0011 18.4 8.4 2.1 1 1 1 2 2 2 2 Uncharacterised MFS-type transporter YbfB DAO PF01266.24 AAZ37620.1 - 4.1e-43 148.3 0.3 4.7e-43 148.1 0.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.16 AAZ37620.1 - 0.00032 20.4 0.1 0.00066 19.3 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 AAZ37620.1 - 0.00067 19.0 0.3 0.041 13.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 AAZ37620.1 - 0.0017 18.3 0.3 0.0037 17.2 0.1 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 AAZ37620.1 - 0.0038 17.4 0.0 0.0074 16.5 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase FAD_binding_3 PF01494.19 AAZ37620.1 - 0.0069 15.7 0.7 0.038 13.2 0.3 2.0 2 0 0 2 2 2 1 FAD binding domain UDPG_MGDP_dh_N PF03721.14 AAZ37620.1 - 0.0075 15.9 0.5 0.014 15.0 0.5 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 AAZ37620.1 - 0.0075 15.7 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 AAZ37620.1 - 0.024 13.9 0.2 0.057 12.7 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 AAZ37620.1 - 0.38 11.4 2.3 0.49 11.0 0.1 2.4 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent HI0933_like PF03486.14 AAZ37620.1 - 0.42 9.3 1.6 0.83 8.3 0.1 1.9 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.6 AAZ37620.1 - 2.9 7.9 5.4 1.8 8.6 0.3 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding Peptidase_S8 PF00082.22 AAZ37621.1 - 8.8e-37 127.0 8.4 1.4e-36 126.3 8.4 1.3 1 0 0 1 1 1 1 Subtilase family PATR PF12951.7 AAZ37621.1 - 2.4e-09 37.1 0.6 2.4e-09 37.1 0.6 2.5 2 0 0 2 2 2 1 Passenger-associated-transport-repeat BolA PF01722.18 AAZ37622.1 - 2.3e-23 82.2 0.7 3e-23 81.9 0.7 1.1 1 0 0 1 1 1 1 BolA-like protein Ni_hydr_CYTB PF01292.20 AAZ37624.1 - 1.4e-29 103.0 14.7 1.5e-29 102.9 14.7 1.0 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 DUF2231 PF09990.9 AAZ37624.1 - 0.0053 17.2 8.5 0.64 10.5 3.5 2.5 1 1 1 2 2 2 2 Predicted membrane protein (DUF2231) DUF4405 PF14358.6 AAZ37624.1 - 0.018 15.6 6.0 0.018 15.6 6.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4405) Cytochrom_B561 PF03188.16 AAZ37624.1 - 0.097 12.8 5.1 0.042 14.0 1.5 2.0 2 1 0 2 2 2 0 Eukaryotic cytochrome b561 N_methyl PF07963.12 AAZ37625.1 - 4.8e-07 29.1 3.4 8.7e-07 28.2 3.4 1.5 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif T2SSJ PF11612.8 AAZ37625.1 - 0.00014 22.1 0.2 0.00041 20.6 0.0 1.8 2 1 0 2 2 2 1 Type II secretion system (T2SS), protein J ABC-3 PF00950.17 AAZ37626.1 - 3.9e-76 256.0 28.9 4.3e-76 255.8 28.9 1.0 1 0 0 1 1 1 1 ABC 3 transport family FecCD PF01032.18 AAZ37626.1 - 7.2e-06 25.2 33.6 2.2e-05 23.7 33.6 1.7 1 1 0 1 1 1 1 FecCD transport family DUF2384 PF09722.10 AAZ37627.1 - 5e-09 36.0 1.5 8.6e-09 35.3 0.1 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF2384) MFS_1 PF07690.16 AAZ37628.1 - 1.3e-22 80.3 63.0 1.4e-15 57.1 42.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SLATT_3 PF18184.1 AAZ37628.1 - 0.074 13.2 0.3 0.18 11.9 0.3 1.6 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 3 DEFB136 PF17333.2 AAZ37628.1 - 0.34 10.9 1.9 20 5.2 0.1 2.4 2 0 0 2 2 2 0 Beta defensin 136 PhoR PF11808.8 AAZ37629.1 - 4.1e-28 97.6 3.0 7.8e-28 96.7 3.0 1.5 1 0 0 1 1 1 1 Phosphate regulon sensor protein PhoR HATPase_c PF02518.26 AAZ37629.1 - 1.3e-23 83.6 0.0 3.6e-23 82.2 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAZ37629.1 - 1.4e-18 66.7 0.1 1.4e-18 66.7 0.1 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 AAZ37629.1 - 2.9e-07 30.3 0.1 2.7e-06 27.3 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 AAZ37629.1 - 3.1e-07 30.4 0.0 7.1e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AAZ37629.1 - 4.7e-05 23.6 0.0 0.0001 22.5 0.0 1.6 1 0 0 1 1 1 1 PAS domain HATPase_c_2 PF13581.6 AAZ37629.1 - 0.00016 21.6 0.0 0.00039 20.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain PAS_7 PF12860.7 AAZ37629.1 - 0.0027 17.8 0.0 0.0083 16.3 0.0 1.8 1 0 0 1 1 1 1 PAS fold HATPase_c_5 PF14501.6 AAZ37629.1 - 0.0065 16.4 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 GHKL domain PAS_4 PF08448.10 AAZ37629.1 - 0.011 16.0 0.0 0.032 14.5 0.0 1.9 1 0 0 1 1 1 0 PAS fold PAS_10 PF13596.6 AAZ37629.1 - 0.1 13.2 0.0 0.42 11.2 0.0 1.9 2 0 0 2 2 2 0 PAS domain DUF3971 PF13116.6 AAZ37630.1 - 4e-56 190.7 0.0 9.4e-56 189.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function AsmA_2 PF13502.6 AAZ37630.1 - 4.3e-48 163.8 2.6 1e-47 162.6 1.0 2.6 2 0 0 2 2 2 1 AsmA-like C-terminal region AsmA PF05170.14 AAZ37630.1 - 0.015 14.1 0.1 0.04 12.7 0.0 1.6 2 0 0 2 2 2 0 AsmA family SmpB PF01668.18 AAZ37631.1 - 1.2e-58 197.0 0.7 1.4e-58 196.8 0.7 1.0 1 0 0 1 1 1 1 SmpB protein TrkA_N PF02254.18 AAZ37632.1 - 0.00013 22.2 0.0 0.00015 22.0 0.0 1.0 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.18 AAZ37632.1 - 0.00024 21.0 0.2 0.00024 21.0 0.2 1.0 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 AAZ37632.1 - 0.00031 21.3 0.1 0.00032 21.2 0.1 1.1 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 AAZ37632.1 - 0.00033 20.1 0.1 0.00036 19.9 0.1 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 AAZ37632.1 - 0.00043 20.5 0.1 0.00049 20.4 0.1 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 AAZ37632.1 - 0.0016 18.1 0.1 0.0018 17.9 0.1 1.0 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA adh_short PF00106.25 AAZ37632.1 - 0.0033 16.9 0.1 0.0039 16.7 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase AlaDh_PNT_C PF01262.21 AAZ37632.1 - 0.0095 15.3 0.3 0.0098 15.2 0.3 1.0 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_Gly3P_dh_N PF01210.23 AAZ37632.1 - 0.012 15.6 0.1 0.013 15.5 0.1 1.0 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DAO PF01266.24 AAZ37632.1 - 0.023 14.3 0.0 0.025 14.2 0.0 1.0 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_2 PF03446.15 AAZ37632.1 - 0.039 14.1 0.0 0.04 14.1 0.0 1.0 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Ldh_1_N PF00056.23 AAZ37632.1 - 0.079 13.1 0.1 0.088 12.9 0.1 1.1 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Sec66 PF09802.9 AAZ37632.1 - 0.082 12.5 0.0 0.083 12.5 0.0 1.0 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 PP-binding PF00550.25 AAZ37633.1 - 6.3e-12 45.7 0.2 7.3e-12 45.5 0.2 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF1493 PF07377.12 AAZ37633.1 - 0.036 14.5 0.3 0.037 14.5 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF2790 PF10976.8 AAZ37635.1 - 9.9e-28 96.0 0.6 1.6e-27 95.3 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2790) DUF778 PF05608.12 AAZ37635.1 - 0.08 13.3 0.0 0.085 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF778) DUF2388 PF09498.10 AAZ37636.1 - 4.6e-30 103.4 4.9 4.6e-30 103.4 4.9 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2388) HBS1_N PF08938.10 AAZ37636.1 - 0.08 13.3 0.1 0.15 12.4 0.1 1.6 1 1 0 1 1 1 0 HBS1 N-terminus AlaDh_PNT_C PF01262.21 AAZ37637.1 - 3.1e-75 252.1 4.4 6.8e-75 251.0 2.2 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 AAZ37637.1 - 4.6e-41 140.3 0.2 1.4e-40 138.7 0.1 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain 2-Hacid_dh_C PF02826.19 AAZ37637.1 - 0.00012 21.5 0.0 0.12 11.7 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 AAZ37637.1 - 0.042 14.1 0.3 8.8 6.7 0.3 2.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain IF-2B PF01008.17 AAZ37638.1 - 3.9e-72 242.8 0.0 4.6e-72 242.6 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Response_reg PF00072.24 AAZ37639.1 - 4.6e-22 78.3 0.0 9.1e-22 77.3 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AAZ37639.1 - 5.3e-13 48.3 0.1 8.9e-13 47.6 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AAZ37639.1 - 4.2e-05 23.1 0.0 0.0001 21.9 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 AAZ37639.1 - 0.049 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Sigma70_r4 PF04545.16 AAZ37639.1 - 0.063 12.8 0.0 0.46 10.0 0.0 2.4 1 1 1 2 2 2 0 Sigma-70, region 4 HTH_38 PF13936.6 AAZ37639.1 - 0.074 12.8 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain zf-RING_9 PF13901.6 AAZ37639.1 - 0.093 12.7 2.1 2.5 8.0 0.1 2.3 2 1 0 2 2 2 0 Putative zinc-RING and/or ribbon HTH_7 PF02796.15 AAZ37639.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase ECH_1 PF00378.20 AAZ37640.1 - 7.8e-48 163.0 0.0 9.4e-48 162.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AAZ37640.1 - 2e-33 116.3 0.1 1.5e-29 103.5 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase CTD PF12815.7 AAZ37640.1 - 0.12 13.0 0.3 0.27 11.8 0.3 1.6 1 1 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 D-ser_dehydrat PF14031.6 AAZ37641.1 - 2.9e-14 53.5 0.0 7.1e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 AAZ37641.1 - 2.8e-12 46.8 0.5 4.1e-12 46.2 0.5 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Hydrolase_3 PF08282.12 AAZ37642.1 - 0.17 11.6 0.0 13 5.4 0.0 2.5 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase BPD_transp_1 PF00528.22 AAZ37643.1 - 8.7e-19 68.0 15.8 8.7e-19 68.0 15.8 1.8 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component LSDAT_prok PF18171.1 AAZ37643.1 - 0.17 11.1 0.1 0.25 10.6 0.1 1.2 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote Urocanase_C PF17392.2 AAZ37644.1 - 8.1e-93 309.3 0.1 1.4e-92 308.6 0.1 1.4 1 0 0 1 1 1 1 Urocanase C-terminal domain Urocanase PF01175.18 AAZ37644.1 - 9.4e-87 290.1 0.0 1.3e-86 289.6 0.0 1.2 1 0 0 1 1 1 1 Urocanase Rossmann-like domain Urocanase_N PF17391.2 AAZ37644.1 - 8.3e-62 206.5 0.1 1.4e-61 205.8 0.1 1.4 1 0 0 1 1 1 1 Urocanase N-terminal domain SIKE PF05769.11 AAZ37645.1 - 0.084 12.8 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 SIKE family MFS_1 PF07690.16 AAZ37646.1 - 1.9e-56 191.5 36.8 8.2e-47 159.8 17.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TruB-C_2 PF09157.11 AAZ37646.1 - 0.02 14.9 0.0 0.036 14.1 0.0 1.3 1 0 0 1 1 1 0 Pseudouridine synthase II TruB, C-terminal GGDEF PF00990.21 AAZ37647.1 - 3.5e-46 156.9 0.0 7e-46 155.9 0.0 1.5 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain dCache_1 PF02743.18 AAZ37647.1 - 1.4e-14 54.5 0.1 2e-14 54.0 0.1 1.2 1 0 0 1 1 1 1 Cache domain DUF4791 PF16039.5 AAZ37647.1 - 0.061 12.9 0.2 7.7 6.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4791) DUF4381 PF14316.6 AAZ37647.1 - 1.1 9.5 5.2 1.5 9.1 2.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) NUDIX_4 PF14815.6 AAZ37648.1 - 4.4e-22 78.2 0.4 9.3e-22 77.1 0.4 1.5 1 0 0 1 1 1 1 NUDIX domain HhH-GPD PF00730.25 AAZ37648.1 - 6.1e-20 71.7 0.0 9.4e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 AAZ37648.1 - 8.5e-06 25.4 0.0 2.1e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 AAZ37648.1 - 0.61 10.5 5.6 1.1 9.7 5.6 1.4 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III HTH_18 PF12833.7 AAZ37649.1 - 1.5e-21 76.4 1.2 2.5e-21 75.7 1.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAZ37649.1 - 2.2e-08 34.0 0.8 0.0068 16.5 0.0 2.7 3 0 0 3 3 3 2 Bacterial regulatory helix-turn-helix proteins, AraC family AraC_binding_2 PF14525.6 AAZ37649.1 - 0.0081 15.9 0.1 0.0081 15.9 0.1 1.9 2 1 0 2 2 2 1 AraC-binding-like domain AraC_binding PF02311.19 AAZ37649.1 - 0.009 15.9 0.5 0.021 14.7 0.1 1.8 1 1 1 2 2 2 1 AraC-like ligand binding domain HTH_AsnC-type PF13404.6 AAZ37649.1 - 0.029 14.2 2.3 1.1 9.2 0.1 3.0 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain Cupin_2 PF07883.11 AAZ37649.1 - 0.1 12.3 0.1 0.21 11.3 0.1 1.5 1 1 0 1 1 1 0 Cupin domain Zn_peptidase_2 PF04298.12 AAZ37650.1 - 0.22 10.9 1.9 0.21 10.9 0.3 1.6 1 1 1 2 2 2 0 Putative neutral zinc metallopeptidase SnoaL_2 PF12680.7 AAZ37651.1 - 7.5e-16 58.6 0.3 1e-15 58.2 0.3 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 AAZ37651.1 - 1.1e-06 28.5 0.1 2e-06 27.6 0.1 1.4 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_3 PF13474.6 AAZ37651.1 - 0.00011 22.4 0.0 0.00016 21.9 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF2358 PF10184.9 AAZ37651.1 - 0.00035 20.8 0.0 0.00047 20.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) LEH PF07858.12 AAZ37651.1 - 0.00047 20.3 0.0 0.00075 19.6 0.0 1.3 1 1 0 1 1 1 1 Limonene-1,2-epoxide hydrolase catalytic domain DUF4440 PF14534.6 AAZ37651.1 - 0.0046 17.3 0.0 0.0061 17.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) NTF2 PF02136.20 AAZ37651.1 - 0.005 17.4 0.0 0.0069 16.9 0.0 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain NUDIX PF00293.28 AAZ37652.1 - 2.2e-10 40.7 0.0 2.5e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain T6SS_TssG PF06996.11 AAZ37653.1 - 5.9e-103 344.2 0.8 6.7e-103 344.0 0.8 1.0 1 0 0 1 1 1 1 Type VI secretion, TssG Glutaminase PF04960.15 AAZ37654.1 - 4.2e-110 367.4 0.0 4.7e-110 367.3 0.0 1.0 1 0 0 1 1 1 1 Glutaminase Sigma70_r2 PF04542.14 AAZ37655.1 - 4.9e-18 64.7 0.6 9.7e-18 63.7 0.6 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 AAZ37655.1 - 9.9e-18 63.6 0.0 2.2e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAZ37655.1 - 4e-09 35.8 0.0 9.3e-09 34.7 0.0 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 AAZ37655.1 - 3.2e-08 33.7 0.1 4.2e-08 33.3 0.1 1.2 1 0 0 1 1 1 1 ECF sigma factor HTH_23 PF13384.6 AAZ37655.1 - 0.0077 16.0 0.0 0.023 14.5 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_16 PF12645.7 AAZ37655.1 - 0.016 15.2 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Phage_antitermQ PF06530.12 AAZ37655.1 - 0.17 11.8 0.0 1.2 9.0 0.0 2.0 2 0 0 2 2 2 0 Phage antitermination protein Q MS_channel PF00924.18 AAZ37656.1 - 3e-34 118.4 0.8 5.7e-34 117.5 0.8 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel FAD_binding_6 PF00970.24 AAZ37657.1 - 5.6e-18 65.1 0.0 1e-17 64.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 AAZ37657.1 - 1.8e-14 54.3 0.0 3.3e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Fer2 PF00111.27 AAZ37657.1 - 1.9e-12 47.0 0.9 3.1e-12 46.3 0.9 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 AAZ37657.1 - 0.0032 17.5 0.0 0.0088 16.1 0.0 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_6 PF08030.12 AAZ37657.1 - 0.03 14.4 0.1 0.18 11.9 0.2 1.8 1 1 1 2 2 2 0 Ferric reductase NAD binding domain DHODB_Fe-S_bind PF10418.9 AAZ37657.1 - 0.036 13.9 2.0 0.095 12.5 2.0 1.6 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B LapA_dom PF06305.11 AAZ37658.1 - 0.0036 17.1 1.2 0.016 15.0 0.5 2.1 2 0 0 2 2 2 1 Lipopolysaccharide assembly protein A domain CD225 PF04505.12 AAZ37658.1 - 0.73 10.0 4.1 4.5 7.5 0.2 2.2 2 0 0 2 2 2 0 Interferon-induced transmembrane protein ADH_zinc_N PF00107.26 AAZ37659.1 - 2.9e-19 69.3 0.1 4.8e-19 68.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AAZ37659.1 - 4.4e-14 53.7 0.0 7e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AAZ37659.1 - 2.2e-10 40.4 0.0 1.5e-09 37.7 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 AAZ37659.1 - 0.019 14.9 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase PD-C2-AF1 PF09310.10 AAZ37659.1 - 0.037 13.4 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 POU domain, class 2, associating factor 1 FlgD PF03963.14 AAZ37660.1 - 2.8e-21 75.6 11.7 7.1e-21 74.3 11.7 1.7 1 0 0 1 1 1 1 Flagellar hook capping protein - N-terminal region FlgD_ig PF13860.6 AAZ37660.1 - 8.5e-20 70.4 5.0 1.3e-19 69.9 3.5 2.0 1 1 1 2 2 2 1 FlgD Ig-like domain FLgD_tudor PF13861.6 AAZ37660.1 - 5.1e-16 58.6 5.9 1.1e-15 57.6 5.9 1.6 1 0 0 1 1 1 1 FlgD Tudor-like domain DUF2271 PF10029.9 AAZ37660.1 - 0.00025 20.7 0.1 0.00057 19.5 0.1 1.6 2 0 0 2 2 2 1 Predicted periplasmic protein (DUF2271) La PF05383.17 AAZ37660.1 - 0.12 12.4 0.1 0.28 11.3 0.1 1.6 1 1 0 1 1 1 0 La domain GSDH PF07995.11 AAZ37661.1 - 2.2e-15 56.8 0.6 2.4e-14 53.4 0.6 2.4 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase NHL PF01436.21 AAZ37661.1 - 3.1e-06 26.9 1.8 2.1 8.5 0.0 4.6 4 0 0 4 4 4 3 NHL repeat Polyketide_cyc PF03364.20 AAZ37662.1 - 1.2e-15 57.8 0.2 1.6e-15 57.5 0.2 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 AAZ37662.1 - 3.1e-06 27.5 0.0 3.7e-06 27.3 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Amino_oxidase PF01593.24 AAZ37663.1 - 9e-38 130.7 2.4 6.1e-37 128.0 2.4 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 AAZ37663.1 - 1.7e-10 40.9 0.3 8e-10 38.8 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 AAZ37663.1 - 8.4e-07 28.6 5.2 0.0017 17.7 1.5 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 AAZ37663.1 - 1.1e-06 28.5 5.8 1e-05 25.3 5.8 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AAZ37663.1 - 2.5e-05 23.6 0.3 4.7e-05 22.6 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 AAZ37663.1 - 0.00017 21.0 0.2 0.00071 18.9 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 AAZ37663.1 - 0.0025 17.1 0.2 0.011 15.0 0.1 1.9 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 AAZ37663.1 - 0.0026 16.6 0.1 0.0038 16.0 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 AAZ37663.1 - 0.003 17.0 1.1 0.0045 16.4 0.3 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 AAZ37663.1 - 0.0037 17.8 0.3 0.014 15.9 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 AAZ37663.1 - 0.0068 15.7 0.7 0.041 13.2 0.3 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 AAZ37663.1 - 0.06 12.4 0.1 0.1 11.7 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A MtrD PF04207.12 AAZ37663.1 - 0.06 13.0 0.2 0.1 12.3 0.2 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit D Glu_dehyd_C PF16912.5 AAZ37663.1 - 0.065 12.7 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Lycopene_cycl PF05834.12 AAZ37663.1 - 0.089 11.8 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein tRNA-synt_2b PF00587.25 AAZ37664.1 - 5.1e-35 121.1 0.0 7.2e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 AAZ37664.1 - 1.9e-29 102.1 0.9 2.9e-29 101.5 0.9 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Filament PF00038.21 AAZ37664.1 - 0.012 15.3 0.4 0.016 14.8 0.4 1.1 1 0 0 1 1 1 0 Intermediate filament protein DUF3450 PF11932.8 AAZ37664.1 - 0.044 13.1 1.1 0.071 12.4 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4201 PF13870.6 AAZ37664.1 - 0.1 12.3 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Cep57_CLD_2 PF14197.6 AAZ37664.1 - 0.13 12.3 1.2 0.29 11.2 1.2 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 V_ATPase_I PF01496.19 AAZ37664.1 - 0.29 9.0 0.1 0.39 8.6 0.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LysR_substrate PF03466.20 AAZ37665.1 - 1e-39 136.1 0.0 1.3e-39 135.7 0.0 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ37665.1 - 4.1e-16 58.7 0.0 7.6e-16 57.8 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AAZ37665.1 - 0.025 14.4 0.0 0.062 13.1 0.0 1.7 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Hydrolase PF00702.26 AAZ37666.1 - 3.4e-05 24.3 0.0 5.5e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 AAZ37666.1 - 0.00052 20.1 0.0 0.00096 19.3 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 AAZ37666.1 - 0.068 13.6 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase EH_Signature PF15611.6 AAZ37666.1 - 0.21 11.0 0.0 0.64 9.4 0.0 1.7 2 0 0 2 2 2 0 EH_Signature domain Metallophos PF00149.28 AAZ37667.1 - 7.9e-05 23.2 0.1 0.00014 22.4 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AAZ37667.1 - 0.00015 22.0 0.8 0.00023 21.4 0.8 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Abhydrolase_6 PF12697.7 AAZ37668.1 - 0.049 14.2 0.0 0.084 13.5 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 AAZ37668.1 - 0.06 12.2 0.0 0.075 11.9 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme rve PF00665.26 AAZ37669.1 - 7.5e-14 52.0 0.0 1.7e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain HTH_23 PF13384.6 AAZ37669.1 - 8.3e-05 22.3 0.0 0.00023 20.8 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain DUF1804 PF08822.11 AAZ37669.1 - 0.00057 19.9 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1804) HTH_3 PF01381.22 AAZ37669.1 - 0.001 19.1 0.0 0.0029 17.6 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix Sigma70_r4 PF04545.16 AAZ37669.1 - 0.0029 17.1 0.1 0.0085 15.6 0.1 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_29 PF13551.6 AAZ37669.1 - 0.0092 16.0 0.0 0.027 14.5 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_36 PF13730.6 AAZ37669.1 - 0.0098 15.8 0.1 0.022 14.7 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_40 PF14493.6 AAZ37669.1 - 0.025 15.0 0.0 0.073 13.5 0.0 1.9 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_17 PF12728.7 AAZ37669.1 - 0.035 14.3 0.0 0.09 13.0 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_38 PF13936.6 AAZ37669.1 - 0.037 13.8 0.9 0.082 12.7 0.2 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain DUF746 PF05344.11 AAZ37669.1 - 0.043 13.6 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) HTH_Tnp_1 PF01527.20 AAZ37669.1 - 0.045 14.1 0.0 0.13 12.5 0.0 1.8 1 0 0 1 1 1 0 Transposase HTH_30 PF13556.6 AAZ37669.1 - 0.063 13.1 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_28 PF13518.6 AAZ37669.1 - 0.069 13.3 0.1 0.18 11.9 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_11 PF08279.12 AAZ37669.1 - 0.12 12.3 0.1 0.25 11.3 0.1 1.5 1 0 0 1 1 1 0 HTH domain MerR PF00376.23 AAZ37669.1 - 0.16 11.8 0.0 0.45 10.3 0.0 1.7 1 0 0 1 1 1 0 MerR family regulatory protein Sigma70_r4_2 PF08281.12 AAZ37669.1 - 0.17 11.6 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 OprD PF03573.13 AAZ37670.1 - 1.9e-148 494.7 7.6 2.2e-148 494.5 7.6 1.0 1 0 0 1 1 1 1 outer membrane porin, OprD family Acyl-CoA_dh_C PF12806.7 AAZ37671.1 - 8.9e-35 119.5 2.7 2e-34 118.4 2.7 1.6 1 0 0 1 1 1 1 Acetyl-CoA dehydrogenase C-terminal like Acyl-CoA_dh_1 PF00441.24 AAZ37671.1 - 3.4e-21 76.0 1.2 3.4e-21 76.0 1.2 3.3 3 1 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 AAZ37671.1 - 2.9e-17 62.6 0.2 4e-16 59.0 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 AAZ37671.1 - 1.9e-12 47.8 0.1 5.7e-12 46.3 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain AcylCoA_DH_N PF12418.8 AAZ37671.1 - 4.2e-10 39.5 0.1 9.1e-10 38.4 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase N terminal Catalase PF00199.19 AAZ37672.1 - 3.5e-07 29.7 0.0 1.5e-06 27.5 0.0 1.8 1 1 0 1 1 1 1 Catalase Topoisom_bac PF01131.20 AAZ37674.1 - 2.6e-127 425.3 0.0 3.6e-127 424.8 0.0 1.2 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 AAZ37674.1 - 8.5e-33 112.7 0.0 1.8e-32 111.6 0.0 1.6 1 0 0 1 1 1 1 Toprim domain Topo_Zn_Ribbon PF08272.11 AAZ37674.1 - 1.7e-30 104.4 0.2 1.8e-16 59.5 0.7 2.7 2 0 0 2 2 2 2 Topoisomerase I zinc-ribbon-like zf-C4_Topoisom PF01396.19 AAZ37674.1 - 5.9e-17 61.2 18.9 2.4e-12 46.4 4.2 4.4 4 1 0 4 4 4 2 Topoisomerase DNA binding C4 zinc finger Zn_ribbon_recom PF13408.6 AAZ37674.1 - 0.088 13.3 7.5 0.92 10.1 0.1 3.6 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain Toprim_4 PF13662.6 AAZ37674.1 - 0.18 12.3 0.1 1.7 9.2 0.0 2.6 3 1 0 3 3 3 0 Toprim domain MFS_1 PF07690.16 AAZ37675.1 - 7.6e-36 123.7 71.1 7.9e-36 123.7 64.2 2.8 2 1 1 3 3 3 3 Major Facilitator Superfamily Transposase_mut PF00872.18 AAZ37676.1 - 1.5e-117 392.7 0.0 1.9e-117 392.3 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ37676.1 - 7.7e-05 23.0 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain DUF4844 PF16133.5 AAZ37676.1 - 0.23 12.0 0.0 0.55 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) cobW PF02492.19 AAZ37677.1 - 3.7e-41 140.7 0.0 5e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 AAZ37677.1 - 1.5e-19 69.7 0.0 3.2e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_22 PF13401.6 AAZ37677.1 - 0.0069 16.7 0.0 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AAZ37677.1 - 0.027 15.0 0.0 0.068 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 AAZ37677.1 - 0.041 13.6 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 AAZ37677.1 - 0.07 13.3 0.1 0.2 11.8 0.0 1.8 2 1 0 2 2 2 0 AAA domain SRPRB PF09439.10 AAZ37677.1 - 0.072 12.5 0.1 0.78 9.1 0.1 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 AAZ37677.1 - 0.1 12.5 0.1 9.5 6.1 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_28 PF13521.6 AAZ37677.1 - 0.15 12.3 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 AAZ37677.1 - 0.19 11.6 0.0 0.31 10.9 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 AAZ37677.1 - 0.2 11.5 1.1 0.71 9.8 0.1 2.4 3 1 0 3 3 3 0 NACHT domain NUDIX PF00293.28 AAZ37678.1 - 7.7e-13 48.6 0.0 9.4e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain OPT PF03169.15 AAZ37679.1 - 3.4e-96 323.3 50.7 1.7e-95 321.0 50.7 1.8 1 1 0 1 1 1 1 OPT oligopeptide transporter protein Glycos_transf_1 PF00534.20 AAZ37680.1 - 6.3e-23 81.2 0.0 1.2e-22 80.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAZ37680.1 - 6.8e-21 75.1 0.0 1.7e-20 73.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAZ37680.1 - 4e-09 36.7 0.2 2.2e-08 34.3 0.2 2.2 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 AAZ37680.1 - 1.9e-07 31.4 0.0 4e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 AAZ37680.1 - 0.00054 20.4 5.8 0.031 14.7 0.0 3.2 2 2 1 3 3 3 2 Glycosyl transferase 4-like domain TonB_C PF03544.14 AAZ37681.1 - 8.2e-12 45.4 0.1 1.4e-11 44.7 0.1 1.3 1 0 0 1 1 1 1 Gram-negative bacterial TonB protein C-terminal HATPase_c PF02518.26 AAZ37682.1 - 3.6e-17 62.9 0.0 1.5e-16 60.9 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAZ37682.1 - 5.5e-14 51.9 0.8 1.7e-13 50.4 0.8 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 AAZ37682.1 - 5.6e-08 33.0 0.0 1.5e-07 31.6 0.0 1.7 1 1 0 1 1 1 1 PAS domain PAS_4 PF08448.10 AAZ37682.1 - 3.3e-06 27.3 0.2 9.8e-06 25.8 0.1 1.9 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 AAZ37682.1 - 6.1e-05 23.0 0.0 0.00017 21.6 0.0 1.8 1 0 0 1 1 1 1 PAS fold HATPase_c_5 PF14501.6 AAZ37682.1 - 0.0016 18.3 0.0 0.0039 17.1 0.0 1.6 1 0 0 1 1 1 1 GHKL domain PAS_8 PF13188.7 AAZ37682.1 - 0.011 15.7 0.0 0.035 14.1 0.0 1.9 1 0 0 1 1 1 0 PAS domain NMT1_2 PF13379.6 AAZ37684.1 - 3.6e-37 128.4 0.2 5e-37 128.0 0.2 1.1 1 0 0 1 1 1 1 NMT1-like family Lipoprotein_9 PF03180.14 AAZ37684.1 - 0.00031 19.9 0.1 0.00099 18.3 0.0 1.8 2 0 0 2 2 2 1 NLPA lipoprotein NMT1 PF09084.11 AAZ37684.1 - 0.0008 19.4 0.3 0.0065 16.4 0.4 2.2 2 1 0 2 2 2 1 NMT1/THI5 like OpuAC PF04069.12 AAZ37684.1 - 0.005 16.4 0.6 0.012 15.2 0.3 1.6 1 1 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system FIVAR PF07554.13 AAZ37684.1 - 3.1 8.6 5.9 0.54 11.0 0.7 2.3 3 0 0 3 3 3 0 FIVAR domain GTP-bdg_N PF13167.6 AAZ37685.1 - 7e-30 103.5 0.0 1.4e-29 102.6 0.0 1.5 1 0 0 1 1 1 1 GTP-binding GTPase N-terminal GTP-bdg_M PF16360.5 AAZ37685.1 - 2.8e-28 98.3 10.8 5.7e-28 97.3 10.8 1.5 1 0 0 1 1 1 1 GTP-binding GTPase Middle Region MMR_HSR1 PF01926.23 AAZ37685.1 - 1.5e-20 73.4 0.0 6.2e-20 71.4 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AAZ37685.1 - 9.6e-05 22.0 0.0 0.00015 21.3 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B GAD PF02938.14 AAZ37685.1 - 0.00017 21.8 0.0 0.0091 16.2 0.0 2.9 3 0 0 3 3 3 1 GAD domain Arf PF00025.21 AAZ37685.1 - 0.00055 19.4 0.0 0.0056 16.1 0.0 2.2 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1_Xtn PF16897.5 AAZ37685.1 - 0.0061 16.6 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 AAZ37685.1 - 0.02 14.8 0.0 2.2 8.2 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Dynamin_N PF00350.23 AAZ37685.1 - 0.033 14.2 0.0 0.065 13.3 0.0 1.6 1 0 0 1 1 1 0 Dynamin family GTP_EFTU PF00009.27 AAZ37685.1 - 0.048 13.2 0.0 4.5 6.8 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 AAZ37685.1 - 0.099 12.4 0.0 0.84 9.4 0.0 2.2 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein Peptidase_M24 PF00557.24 AAZ37686.1 - 3.1e-53 180.6 0.2 3.5e-53 180.4 0.2 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 BPD_transp_2 PF02653.16 AAZ37687.1 - 7.5e-57 192.5 40.5 8.8e-57 192.3 40.5 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component SLATT_fungal PF18142.1 AAZ37687.1 - 7 6.7 6.3 28 4.7 5.6 2.2 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain Sugar_tr PF00083.24 AAZ37688.1 - 9.3e-44 150.0 16.7 1.4e-43 149.4 16.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 AAZ37688.1 - 4.7e-33 114.6 69.5 9.6e-28 97.1 36.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 AAZ37688.1 - 1.8e-06 27.5 9.7 1.8e-06 27.5 9.7 2.9 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 AAZ37688.1 - 0.00019 20.4 22.5 0.031 13.1 5.8 2.8 1 1 0 2 2 2 2 MFS_1 like family OATP PF03137.20 AAZ37688.1 - 0.0086 14.4 6.1 0.8 7.9 0.4 3.1 2 1 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family LapA_dom PF06305.11 AAZ37688.1 - 0.13 12.1 0.2 0.13 12.1 0.2 5.5 7 0 0 7 7 7 0 Lipopolysaccharide assembly protein A domain Oxidored_FMN PF00724.20 AAZ37689.1 - 2.7e-74 250.5 0.0 3.3e-74 250.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 AAZ37689.1 - 6.2e-06 25.5 0.0 1.8e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 AAZ37689.1 - 0.0063 16.0 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein NanE PF04131.14 AAZ37689.1 - 0.011 14.9 0.0 0.021 14.0 0.0 1.4 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase IMPDH PF00478.25 AAZ37689.1 - 0.06 12.3 0.8 0.26 10.2 0.3 2.0 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain BPD_transp_1 PF00528.22 AAZ37690.1 - 1.1e-21 77.4 13.3 1.4e-21 77.1 13.3 1.1 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component Acyl-CoA_dh_M PF02770.19 AAZ37691.1 - 2.6e-13 50.0 0.0 5.4e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 AAZ37691.1 - 3.1e-11 43.7 0.8 7.1e-11 42.5 0.0 2.0 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 AAZ37691.1 - 1.1e-06 29.3 0.0 2.1e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 AAZ37691.1 - 2.1e-06 28.0 0.0 4.9e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Phasin PF05597.11 AAZ37693.1 - 5e-46 155.8 3.4 5e-46 155.8 3.4 2.1 2 0 0 2 2 2 1 Poly(hydroxyalcanoate) granule associated protein (phasin) Mitofilin PF09731.9 AAZ37693.1 - 0.001 18.0 20.4 0.0014 17.6 20.4 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein HC2 PF07382.11 AAZ37693.1 - 0.0041 17.2 61.9 0.0041 17.2 61.9 2.0 2 0 0 2 2 2 1 Histone H1-like nucleoprotein HC2 Apolipoprotein PF01442.18 AAZ37693.1 - 0.065 13.1 12.9 0.43 10.4 12.9 1.9 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 AAZ37693.1 - 0.071 13.7 20.6 0.29 11.8 0.4 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) K-box PF01486.17 AAZ37693.1 - 0.14 12.4 0.9 5.8 7.2 1.0 2.1 1 1 1 2 2 2 0 K-box region PHA_synth_III_E PF09712.10 AAZ37693.1 - 0.18 10.9 0.0 0.18 10.9 0.0 2.4 2 1 0 2 2 2 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) DUF572 PF04502.13 AAZ37693.1 - 2.1 7.9 12.5 2.9 7.4 12.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF3807 PF12720.7 AAZ37693.1 - 4.4 7.5 9.1 1.2 9.4 2.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) DUF446 PF04287.12 AAZ37694.1 - 3.4e-33 113.6 1.7 3.8e-33 113.5 1.7 1.0 1 0 0 1 1 1 1 tRNA pseudouridine synthase C Glu-tRNAGln PF02686.15 AAZ37695.1 - 2.3e-18 66.2 0.1 3.3e-18 65.7 0.1 1.2 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit SLAC1 PF03595.17 AAZ37696.1 - 1.5e-81 274.2 51.4 1.8e-81 274.0 51.4 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel PhoH PF02562.16 AAZ37697.1 - 6.3e-45 153.2 0.0 9.6e-45 152.6 0.0 1.2 1 0 0 1 1 1 1 PhoH-like protein PIN_4 PF13638.6 AAZ37697.1 - 5.3e-38 130.3 0.1 8.6e-38 129.6 0.1 1.3 1 0 0 1 1 1 1 PIN domain AAA_30 PF13604.6 AAZ37697.1 - 8.2e-07 28.9 0.0 1.9e-06 27.7 0.0 1.5 2 0 0 2 2 2 1 AAA domain Zot PF05707.12 AAZ37697.1 - 5.2e-05 23.0 0.0 0.0012 18.5 0.0 2.6 2 1 0 2 2 2 1 Zonular occludens toxin (Zot) NB-ARC PF00931.22 AAZ37697.1 - 0.0059 15.8 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain PIN_9 PF18477.1 AAZ37697.1 - 0.0077 16.5 0.5 0.39 11.0 0.1 2.6 2 0 0 2 2 2 1 PIN like domain AAA_19 PF13245.6 AAZ37697.1 - 0.0091 16.3 0.3 0.09 13.1 0.3 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAZ37697.1 - 0.017 15.5 0.0 0.049 14.0 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain DEAD PF00270.29 AAZ37697.1 - 0.02 14.7 0.2 4.6 7.0 0.0 2.7 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_22 PF13401.6 AAZ37697.1 - 0.021 15.1 0.6 0.15 12.4 0.2 2.6 2 1 0 2 2 1 0 AAA domain Viral_helicase1 PF01443.18 AAZ37697.1 - 0.038 13.7 0.1 5.7 6.6 0.0 2.5 1 1 1 2 2 2 0 Viral (Superfamily 1) RNA helicase ATPase PF06745.13 AAZ37697.1 - 0.079 12.3 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.27 AAZ37698.1 - 3e-36 125.0 0.0 3.8e-36 124.6 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAZ37698.1 - 1.6e-10 41.3 0.0 0.00024 21.0 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAZ37698.1 - 1e-08 34.9 0.0 3.2e-07 30.0 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 AAZ37698.1 - 1.5e-05 25.0 0.0 2.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 AAZ37698.1 - 2.3e-05 24.8 0.1 3.4e-05 24.3 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AAZ37698.1 - 5.2e-05 23.6 0.0 9.5e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAZ37698.1 - 7.4e-05 22.4 0.0 0.00015 21.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.6 AAZ37698.1 - 0.0005 20.3 0.0 0.0011 19.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AAZ37698.1 - 0.00056 20.5 0.0 0.0012 19.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 AAZ37698.1 - 0.00094 19.2 0.0 0.0013 18.7 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain ATPase_2 PF01637.18 AAZ37698.1 - 0.0065 16.4 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_30 PF13604.6 AAZ37698.1 - 0.0068 16.2 0.0 0.0096 15.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_13 PF13166.6 AAZ37698.1 - 0.0075 15.0 0.0 0.1 11.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 AAZ37698.1 - 0.0096 16.4 0.0 0.092 13.2 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 AAZ37698.1 - 0.014 15.0 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC_ATPase PF09818.9 AAZ37698.1 - 0.021 13.6 0.0 2.7 6.7 0.0 2.3 2 1 0 2 2 2 0 Predicted ATPase of the ABC class APS_kinase PF01583.20 AAZ37698.1 - 0.028 14.3 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_25 PF13481.6 AAZ37698.1 - 0.029 14.0 0.0 0.059 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 AAZ37698.1 - 0.029 13.6 0.0 0.05 12.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_23 PF13476.6 AAZ37698.1 - 0.036 14.6 0.0 0.056 13.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 AAZ37698.1 - 0.042 13.9 0.0 0.082 13.0 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_7 PF12775.7 AAZ37698.1 - 0.045 13.3 0.0 0.077 12.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 AAZ37698.1 - 0.047 14.1 0.0 0.2 12.1 0.0 1.9 2 0 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.12 AAZ37698.1 - 0.048 12.9 0.0 0.077 12.3 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.17 AAZ37698.1 - 0.049 13.4 0.0 0.079 12.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_15 PF13175.6 AAZ37698.1 - 0.057 13.1 0.0 0.17 11.6 0.0 1.4 1 1 1 2 2 2 0 AAA ATPase domain TsaE PF02367.17 AAZ37698.1 - 0.074 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 AAZ37698.1 - 0.083 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 AAZ37698.1 - 0.087 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 AAZ37698.1 - 0.1 11.7 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit TniB PF05621.11 AAZ37698.1 - 0.12 11.8 0.0 0.53 9.7 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein AAA_5 PF07728.14 AAZ37698.1 - 0.12 12.4 0.0 0.33 10.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 AAZ37698.1 - 0.14 12.1 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Septin PF00735.18 AAZ37698.1 - 0.15 11.3 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_28 PF13521.6 AAZ37698.1 - 0.16 12.2 0.0 0.54 10.5 0.0 1.9 3 0 0 3 3 1 0 AAA domain TK PF00265.18 AAZ37698.1 - 0.18 11.7 0.0 3.4 7.5 0.0 2.1 2 0 0 2 2 2 0 Thymidine kinase GSP_synth PF03738.14 AAZ37699.1 - 7.2e-143 476.3 0.0 8.2e-143 476.1 0.0 1.0 1 0 0 1 1 1 1 Glutathionylspermidine synthase preATP-grasp COX7B PF05392.11 AAZ37699.1 - 0.08 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase chain VIIB Aldo_ket_red PF00248.21 AAZ37700.1 - 7.8e-50 169.7 0.0 1.8e-47 162.0 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family LPAM_1 PF08139.12 AAZ37701.1 - 0.059 13.9 3.3 0.16 12.5 3.3 1.7 1 1 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site N_NLPC_P60 PF12912.7 AAZ37701.1 - 0.077 13.4 0.1 0.097 13.0 0.1 1.1 1 0 0 1 1 1 0 NLPC_P60 stabilising domain, N term LPAM_2 PF13627.6 AAZ37701.1 - 6.5 6.7 5.7 12 5.9 5.7 1.5 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site Metallophos PF00149.28 AAZ37702.1 - 7.2e-12 46.2 0.0 1.5e-11 45.2 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AAZ37702.1 - 9.9e-09 35.6 0.0 3.2e-08 33.9 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Peripla_BP_1 PF00532.21 AAZ37704.1 - 5.9e-39 134.2 0.0 7.4e-39 133.8 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_3 PF13377.6 AAZ37704.1 - 2.9e-22 79.7 0.0 1.5e-21 77.4 0.0 1.9 2 0 0 2 2 2 1 Periplasmic binding protein-like domain LacI PF00356.21 AAZ37704.1 - 1.2e-17 63.4 0.0 2e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family B12-binding PF02310.19 AAZ37704.1 - 0.019 15.0 0.0 0.047 13.7 0.0 1.7 1 0 0 1 1 1 0 B12 binding domain HTH_23 PF13384.6 AAZ37704.1 - 0.038 13.8 0.0 0.19 11.6 0.0 2.2 2 1 1 3 3 3 0 Homeodomain-like domain HTH_3 PF01381.22 AAZ37704.1 - 0.073 13.1 0.2 0.17 11.9 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix HTH_Tnp_ISL3 PF13542.6 AAZ37704.1 - 0.086 12.3 0.1 0.16 11.4 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Peripla_BP_4 PF13407.6 AAZ37704.1 - 0.12 12.0 0.0 13 5.2 0.0 2.3 2 1 0 2 2 2 0 Periplasmic binding protein domain DNA_ligase_aden PF01653.18 AAZ37705.1 - 7.2e-128 426.2 0.0 1.1e-127 425.5 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.16 AAZ37705.1 - 1.1e-34 118.2 2.2 2.2e-34 117.2 2.2 1.5 1 0 0 1 1 1 1 NAD-dependent DNA ligase OB-fold domain HHH_2 PF12826.7 AAZ37705.1 - 1.8e-31 108.0 1.0 8.9e-21 73.8 0.0 3.7 5 1 0 5 5 5 2 Helix-hairpin-helix motif HHH_5 PF14520.6 AAZ37705.1 - 8.4e-12 45.5 0.4 0.012 16.2 0.3 3.5 3 0 0 3 3 3 3 Helix-hairpin-helix domain DNA_ligase_ZBD PF03119.16 AAZ37705.1 - 2.7e-11 43.3 1.7 5.5e-11 42.3 1.7 1.6 1 0 0 1 1 1 1 NAD-dependent DNA ligase C4 zinc finger domain BRCT PF00533.26 AAZ37705.1 - 2e-10 40.9 0.0 4.2e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain 5_3_exonuc PF01367.20 AAZ37705.1 - 0.00087 19.8 0.0 0.65 10.6 0.0 3.1 3 0 0 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold HHH PF00633.23 AAZ37705.1 - 0.0043 16.9 0.1 3.3 7.7 0.0 3.6 3 0 0 3 3 3 1 Helix-hairpin-helix motif PTCB-BRCT PF12738.7 AAZ37705.1 - 0.0081 16.1 0.0 0.022 14.7 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain SSF PF00474.17 AAZ37706.1 - 2e-133 445.2 29.6 2e-133 445.2 29.6 1.4 2 0 0 2 2 2 1 Sodium:solute symporter family FliL PF03748.14 AAZ37707.1 - 9.4e-22 77.5 0.3 6.5e-21 74.9 0.2 1.9 2 0 0 2 2 2 1 Flagellar basal body-associated protein FliL MS_channel PF00924.18 AAZ37708.1 - 1.8e-33 115.8 3.5 1.8e-33 115.8 3.5 1.3 2 0 0 2 2 2 1 Mechanosensitive ion channel TM_helix PF05552.12 AAZ37708.1 - 0.0059 16.5 1.1 0.0059 16.5 1.1 3.2 3 0 0 3 3 3 1 Conserved TM helix Bac_export_2 PF01312.19 AAZ37708.1 - 0.26 10.4 4.3 0.46 9.6 4.3 1.4 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family adh_short_C2 PF13561.6 AAZ37709.1 - 1.3e-53 182.0 0.2 1.5e-53 181.8 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAZ37709.1 - 9.4e-44 149.2 0.0 1.2e-43 148.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase DUF1776 PF08643.10 AAZ37709.1 - 0.0015 18.0 0.0 0.0021 17.5 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 AAZ37709.1 - 0.0057 16.1 0.0 0.018 14.5 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDPD PF03009.17 AAZ37710.1 - 4.1e-35 121.8 0.0 6.8e-35 121.0 0.0 1.3 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family UTRA PF07702.13 AAZ37710.1 - 0.14 12.0 0.2 3.4 7.5 0.1 2.2 2 0 0 2 2 2 0 UTRA domain ACP_PD PF04336.12 AAZ37711.1 - 1.9e-31 108.6 0.0 2.9e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 Acyl carrier protein phosphodiesterase Sdh_cyt PF01127.22 AAZ37712.1 - 2.2e-32 111.6 1.6 2.5e-32 111.5 1.6 1.0 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Fumarate_red_D PF02313.17 AAZ37712.1 - 0.002 18.2 2.4 0.0031 17.6 2.4 1.4 1 0 0 1 1 1 1 Fumarate reductase subunit D T4SS_CagC PF16943.5 AAZ37712.1 - 0.21 11.8 3.8 7.4 6.8 0.2 2.4 1 1 1 2 2 2 0 Cag pathogenicity island, type IV secretory system IGPS PF00218.21 AAZ37713.1 - 2.1e-96 322.0 0.1 2.4e-96 321.8 0.1 1.0 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase HAMP PF00672.25 AAZ37713.1 - 0.76 10.2 2.9 4.3 7.8 0.2 2.3 2 0 0 2 2 2 0 HAMP domain NUDIX PF00293.28 AAZ37714.1 - 1.7e-11 44.3 0.0 2.6e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Ribul_P_3_epim PF00834.19 AAZ37715.1 - 1.1e-88 295.9 0.0 1.2e-88 295.7 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 AAZ37715.1 - 1.5e-05 24.8 0.0 0.00073 19.4 0.0 2.2 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.21 AAZ37715.1 - 0.017 14.6 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein OMPdecase PF00215.24 AAZ37715.1 - 0.14 11.7 0.1 0.21 11.2 0.1 1.3 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family HATPase_c PF02518.26 AAZ37716.1 - 4.8e-20 72.2 0.0 9e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase dCache_1 PF02743.18 AAZ37716.1 - 4.6e-18 65.9 0.0 1.1e-17 64.6 0.0 1.7 1 0 0 1 1 1 1 Cache domain HisKA PF00512.25 AAZ37716.1 - 1.3e-06 28.4 0.3 1.3e-06 28.4 0.3 3.2 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain sCache_3_2 PF17203.4 AAZ37716.1 - 0.0051 16.9 0.0 0.63 10.2 0.0 3.0 2 1 0 2 2 2 1 Single cache domain 3 HATPase_c_3 PF13589.6 AAZ37716.1 - 0.0098 15.7 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MnmE_helical PF12631.7 AAZ37716.1 - 0.012 15.8 0.1 0.025 14.8 0.1 1.5 1 0 0 1 1 1 0 MnmE helical domain HATPase_c_5 PF14501.6 AAZ37716.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 GHKL domain Phenyl_P_gamma PF09662.10 AAZ37716.1 - 0.15 12.2 0.1 0.68 10.1 0.0 2.1 2 0 0 2 2 2 0 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) COG5 PF10392.9 AAZ37716.1 - 0.25 11.5 3.8 0.1 12.8 0.9 1.9 2 0 0 2 2 2 0 Golgi transport complex subunit 5 OmpH PF03938.14 AAZ37716.1 - 3.4 8.0 6.6 3 8.2 4.8 1.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) tRNA-synt_1b PF00579.25 AAZ37717.1 - 1.4e-79 267.5 0.0 1.7e-79 267.2 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 AAZ37717.1 - 1.2e-05 24.9 0.1 2.1e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 S4 domain HTH_50 PF18024.1 AAZ37717.1 - 0.11 12.1 0.1 0.52 10.0 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain S4_2 PF13275.6 AAZ37717.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 S4 domain BPD_transp_2 PF02653.16 AAZ37718.1 - 3.1e-45 154.4 40.2 3.1e-45 154.4 40.2 1.4 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component Peptidase_M3 PF01432.20 AAZ37720.1 - 6.5e-153 510.3 0.0 1.7e-152 508.9 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M3 Rubis-subs-bind PF09273.11 AAZ37720.1 - 0.41 11.3 2.9 4.1 8.1 0.0 3.0 2 1 0 3 3 3 0 Rubisco LSMT substrate-binding Peptidase_M50B PF13398.6 AAZ37720.1 - 0.58 9.8 1.4 1 8.9 1.4 1.3 1 0 0 1 1 1 0 Peptidase M50B-like adh_short PF00106.25 AAZ37721.1 - 1.6e-42 145.2 0.1 2.1e-42 144.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAZ37721.1 - 4.4e-30 105.0 0.4 5.5e-30 104.7 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAZ37721.1 - 2.2e-12 47.2 0.3 3e-12 46.8 0.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AAZ37721.1 - 1.8e-06 27.6 0.1 2.7e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 AAZ37721.1 - 0.0012 18.8 0.6 0.0017 18.3 0.6 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 AAZ37721.1 - 0.014 14.8 0.1 0.02 14.3 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase YAcAr PF10686.9 AAZ37721.1 - 0.018 15.0 0.2 0.84 9.6 0.0 2.5 1 1 1 2 2 2 0 YspA, cpYpsA-related SLOG family ApbA PF02558.16 AAZ37721.1 - 0.032 13.9 0.0 0.069 12.8 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA HupE_UreJ PF04955.12 AAZ37722.1 - 6e-62 208.3 27.6 7e-62 208.1 27.6 1.0 1 0 0 1 1 1 1 HupE / UreJ protein HupE_UreJ_2 PF13795.6 AAZ37722.1 - 2.6e-05 23.9 1.9 3.8e-05 23.4 1.4 1.4 1 1 0 1 1 1 1 HupE / UreJ protein PseudoU_synth_2 PF00849.22 AAZ37723.1 - 1.5e-14 54.4 0.1 5e-13 49.4 0.1 2.1 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 AAZ37723.1 - 6.3e-05 22.6 0.0 0.00013 21.6 0.0 1.6 1 1 0 1 1 1 1 S4 domain Ead_Ea22 PF13935.6 AAZ37723.1 - 0.19 12.4 0.0 0.25 12.0 0.0 1.3 1 0 0 1 1 1 0 Ead/Ea22-like protein Mob_synth_C PF06463.13 AAZ37724.1 - 1.6e-38 131.5 0.0 2.8e-38 130.7 0.0 1.4 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 AAZ37724.1 - 9.5e-32 110.7 0.1 1.7e-31 109.9 0.1 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 AAZ37724.1 - 8.8e-08 32.5 0.0 1.6e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AAZ37724.1 - 0.00012 22.2 0.0 0.00022 21.3 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain HIT PF01230.23 AAZ37725.1 - 4.6e-28 97.8 0.0 5.2e-28 97.6 0.0 1.0 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 AAZ37725.1 - 9.4e-23 80.9 0.0 1.1e-22 80.7 0.0 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding SDF PF00375.18 AAZ37726.1 - 9.8e-113 377.1 39.8 1.1e-112 376.9 39.8 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Transposase_mut PF00872.18 AAZ37727.1 - 2e-117 392.3 0.0 2.5e-117 392.0 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ37727.1 - 7.8e-05 23.0 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain Ribonuc_L-PSP PF01042.21 AAZ37728.1 - 2e-25 89.1 0.0 2.3e-25 89.0 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF4096 PF13340.6 AAZ37729.1 - 5.8e-25 87.3 0.4 1.5e-24 86.0 0.4 1.8 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1 PF01609.21 AAZ37729.1 - 3.2e-14 53.1 0.0 5.7e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AAZ37729.1 - 7.2e-10 39.1 0.2 2.1e-09 37.6 0.2 1.9 1 0 0 1 1 1 1 Transposase DDE domain HTH_Tnp_Tc3_2 PF01498.18 AAZ37729.1 - 0.061 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Transposase DUF1161 PF06649.12 AAZ37730.1 - 3.7e-24 84.7 0.5 4.4e-24 84.4 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1161) PepSY_2 PF13670.6 AAZ37730.1 - 0.054 13.5 0.1 0.071 13.1 0.1 1.3 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Tfb5 PF06331.12 AAZ37730.1 - 0.058 13.4 0.0 8.3 6.5 0.0 2.3 2 0 0 2 2 2 0 Transcription factor TFIIH complex subunit Tfb5 Peripla_BP_3 PF13377.6 AAZ37731.1 - 1.2e-28 100.6 2.0 5e-27 95.3 0.1 2.7 2 1 1 3 3 3 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 AAZ37731.1 - 4.3e-22 78.8 0.0 5.6e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_4 PF13407.6 AAZ37731.1 - 6.1e-13 48.9 0.0 1.2e-12 48.0 0.0 1.5 1 1 0 1 1 1 1 Periplasmic binding protein domain LacI PF00356.21 AAZ37731.1 - 7.8e-12 44.8 0.7 1.4e-11 44.0 0.7 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family NinF PF05810.12 AAZ37731.1 - 0.075 12.9 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 NinF protein PilX_N PF14341.6 AAZ37732.1 - 2.5e-13 49.7 2.5 5.8e-13 48.6 2.5 1.7 1 0 0 1 1 1 1 PilX N-terminal PilX PF13681.6 AAZ37732.1 - 0.086 13.2 2.4 0.13 12.7 0.1 2.0 1 1 0 2 2 2 0 Type IV pilus assembly protein PilX C-term Response_reg PF00072.24 AAZ37733.1 - 5.7e-25 87.7 0.1 9e-25 87.0 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AAZ37733.1 - 5.9e-16 57.8 0.0 1.4e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AAZ37733.1 - 1.5e-06 27.8 0.0 3.3e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAZ37733.1 - 2.4e-06 26.9 0.0 5.6e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_24 PF13412.6 AAZ37733.1 - 0.0012 18.3 0.0 0.0083 15.7 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_10 PF04967.12 AAZ37733.1 - 0.021 14.6 0.2 0.24 11.2 0.0 2.6 3 0 0 3 3 3 0 HTH DNA binding domain T4_deiodinase PF00837.17 AAZ37733.1 - 0.051 12.9 0.0 0.11 11.8 0.0 1.4 2 0 0 2 2 2 0 Iodothyronine deiodinase MCPsignal PF00015.21 AAZ37734.1 - 1.1e-43 149.0 26.1 1.1e-43 149.0 26.1 4.1 2 1 2 4 4 4 1 Methyl-accepting chemotaxis protein (MCP) signalling domain 4HB_MCP_1 PF12729.7 AAZ37734.1 - 9.5e-07 28.5 0.0 9.5e-07 28.5 0.0 4.3 3 1 1 4 4 4 1 Four helix bundle sensory module for signal transduction ERM PF00769.19 AAZ37734.1 - 0.28 10.9 20.1 1 9.1 5.4 2.5 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Syntaxin-6_N PF09177.11 AAZ37734.1 - 1 10.0 16.0 12 6.5 0.4 4.6 3 1 1 4 4 4 0 Syntaxin 6, N-terminal DASH_Duo1 PF08651.10 AAZ37734.1 - 2.5 7.9 20.2 0.089 12.6 2.3 5.3 4 2 2 6 6 6 0 DASH complex subunit Duo1 DASH_Dad4 PF08650.10 AAZ37734.1 - 4 7.5 10.2 10 6.2 0.7 4.0 3 1 0 3 3 3 0 DASH complex subunit Dad4 FCD PF07729.12 AAZ37735.1 - 2.4e-22 79.7 4.5 2.4e-22 79.7 4.5 1.9 3 0 0 3 3 3 1 FCD domain GntR PF00392.21 AAZ37735.1 - 9.5e-20 70.0 1.5 9.5e-20 70.0 1.5 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family PaaX PF07848.12 AAZ37735.1 - 0.0025 18.0 0.4 0.0084 16.3 0.2 2.0 2 0 0 2 2 2 1 PaaX-like protein Rrf2 PF02082.20 AAZ37735.1 - 0.0025 18.1 0.1 0.0063 16.8 0.1 1.6 1 0 0 1 1 1 1 Transcriptional regulator MarR_2 PF12802.7 AAZ37735.1 - 0.0043 16.9 0.1 0.0043 16.9 0.1 2.3 3 0 0 3 3 3 1 MarR family HTH_24 PF13412.6 AAZ37735.1 - 0.0062 16.1 0.8 0.022 14.3 0.1 2.2 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding TrmB PF01978.19 AAZ37735.1 - 0.016 15.0 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_41 PF14502.6 AAZ37735.1 - 0.023 14.4 0.1 0.04 13.6 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 AAZ37735.1 - 0.027 14.4 0.5 0.066 13.2 0.4 1.7 1 1 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_11 PF08279.12 AAZ37735.1 - 0.072 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 HTH domain HTH_IclR PF09339.10 AAZ37735.1 - 0.079 12.8 0.4 0.3 10.9 0.1 2.1 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_CodY PF08222.11 AAZ37735.1 - 0.14 11.7 0.1 0.32 10.6 0.1 1.5 1 0 0 1 1 1 0 CodY helix-turn-helix domain DprA_WH PF17782.1 AAZ37735.1 - 1.2 9.3 4.4 8.9 6.5 0.1 3.1 3 0 0 3 3 3 0 DprA winged helix domain Bac_export_2 PF01312.19 AAZ37736.1 - 2.4e-98 329.4 0.4 2.7e-98 329.2 0.4 1.0 1 0 0 1 1 1 1 FlhB HrpN YscU SpaS Family DUF2236 PF09995.9 AAZ37736.1 - 0.099 12.8 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2236) NusG PF02357.19 AAZ37737.1 - 2.3e-18 66.5 0.0 3.2e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Transcription termination factor nusG PGM_PMM_I PF02878.16 AAZ37738.1 - 2e-35 121.5 0.0 3e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 AAZ37738.1 - 8.1e-29 100.3 0.2 2e-28 99.0 0.2 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 AAZ37738.1 - 8.9e-23 80.7 0.0 1.5e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 AAZ37738.1 - 5.2e-14 52.2 0.1 1e-13 51.2 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF2218 PF09981.9 AAZ37738.1 - 0.067 13.6 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2218) Response_reg PF00072.24 AAZ37739.1 - 3.2e-29 101.4 0.0 4.6e-29 100.8 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAZ37739.1 - 1.3e-21 76.5 0.0 2.6e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal GGDEF PF00990.21 AAZ37740.1 - 4.3e-44 150.1 0.0 6.1e-44 149.6 0.0 1.2 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Lig_chan PF00060.26 AAZ37740.1 - 7.7 6.3 6.6 17 5.2 6.7 1.5 1 1 0 1 1 1 0 Ligand-gated ion channel ATP-grasp_4 PF13535.6 AAZ37741.1 - 4.4e-08 32.9 0.0 7.1e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 AAZ37741.1 - 0.00033 20.7 0.0 0.00066 19.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain DUF4096 PF13340.6 AAZ37742.1 - 5.8e-25 87.3 0.4 1.5e-24 86.0 0.4 1.8 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1 PF01609.21 AAZ37742.1 - 3.2e-14 53.1 0.0 5.7e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AAZ37742.1 - 7.2e-10 39.1 0.2 2.1e-09 37.6 0.2 1.9 1 0 0 1 1 1 1 Transposase DDE domain HTH_Tnp_Tc3_2 PF01498.18 AAZ37742.1 - 0.061 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Transposase GTP1_OBG PF01018.22 AAZ37743.1 - 4.7e-60 201.7 4.1 6.5e-60 201.2 4.1 1.2 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 AAZ37743.1 - 1.1e-22 80.3 0.0 4.1e-22 78.4 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AAZ37743.1 - 4e-09 36.2 0.0 2.2e-06 27.3 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B MeaB PF03308.16 AAZ37743.1 - 0.00072 18.6 0.3 0.38 9.7 0.1 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 AAZ37743.1 - 0.054 13.0 0.0 0.4 10.2 0.0 2.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 AAZ37743.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 AAZ37743.1 - 0.18 11.7 0.1 1.2 9.1 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase AAA_31 PF13614.6 AAZ37744.1 - 1.6e-40 138.9 0.0 2.1e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 AAZ37744.1 - 5.7e-20 71.7 0.0 7.1e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 AAZ37744.1 - 6e-10 39.0 2.3 7.5e-09 35.4 2.3 2.2 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase MipZ PF09140.11 AAZ37744.1 - 7.7e-09 35.2 0.0 1.5e-07 30.9 0.0 2.1 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 AAZ37744.1 - 6.6e-08 32.1 0.1 1.9e-07 30.6 0.1 1.7 2 0 0 2 2 2 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 AAZ37744.1 - 1.6e-06 27.8 0.2 8.1e-06 25.5 0.2 1.9 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 AAZ37744.1 - 5.2e-05 22.8 0.0 0.00011 21.8 0.0 1.4 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirC1 PF07015.11 AAZ37744.1 - 0.00015 21.1 0.1 0.00083 18.7 0.0 2.0 2 0 0 2 2 2 1 VirC1 protein CLP1_P PF16575.5 AAZ37744.1 - 0.0028 17.5 0.0 0.005 16.6 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop MeaB PF03308.16 AAZ37744.1 - 0.0046 16.0 0.1 0.0074 15.3 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 AAZ37744.1 - 0.018 14.9 0.0 0.041 13.6 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein LpxK PF02606.14 AAZ37744.1 - 0.034 13.3 0.4 0.055 12.6 0.4 1.2 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase DUF1611 PF07755.11 AAZ37744.1 - 0.068 12.5 0.0 0.23 10.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1611_C) P-loop domain SRP54 PF00448.22 AAZ37744.1 - 0.12 12.0 0.2 0.22 11.2 0.2 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain FTHFS PF01268.19 AAZ37744.1 - 0.13 10.5 0.1 0.16 10.1 0.1 1.1 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase Fer2_BFD PF04324.15 AAZ37745.1 - 9.6e-10 38.7 7.5 1.2e-09 38.4 7.5 1.2 1 0 0 1 1 1 1 BFD-like [2Fe-2S] binding domain SSF PF00474.17 AAZ37746.1 - 4.9e-128 427.5 38.2 4.9e-128 427.5 38.2 1.4 2 0 0 2 2 2 1 Sodium:solute symporter family DUF2818 PF10993.8 AAZ37746.1 - 0.019 15.5 3.7 0.11 13.1 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2818) Vma12 PF11712.8 AAZ37746.1 - 4.9 7.2 4.8 1.2 9.2 0.1 2.4 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase CheW PF01584.19 AAZ37747.1 - 9.5e-37 125.7 0.9 1.4e-36 125.1 0.9 1.3 1 0 0 1 1 1 1 CheW-like domain Response_reg PF00072.24 AAZ37747.1 - 1.2e-15 57.7 0.0 2.1e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Tubulin PF00091.25 AAZ37748.1 - 7.2e-39 134.0 1.9 1.2e-38 133.3 1.9 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.8 AAZ37748.1 - 1e-35 121.9 0.5 2.3e-35 120.7 0.5 1.7 1 0 0 1 1 1 1 FtsZ family, C-terminal domain NmrA PF05368.13 AAZ37748.1 - 0.0029 17.2 0.1 0.36 10.4 0.0 3.0 2 1 1 3 3 3 2 NmrA-like family NAD_binding_10 PF13460.6 AAZ37748.1 - 0.018 15.0 0.2 0.061 13.2 0.0 2.0 2 0 0 2 2 2 0 NAD(P)H-binding Tubulin_2 PF13809.6 AAZ37748.1 - 2.8 7.0 10.6 9.9 5.2 4.9 2.7 1 1 1 2 2 2 0 Tubulin like Phage_cap_P2 PF05125.12 AAZ37749.1 - 1.3e-105 353.0 0.1 1.4e-105 352.9 0.1 1.0 1 0 0 1 1 1 1 Phage major capsid protein, P2 family HxlR PF01638.17 AAZ37750.1 - 1.3e-27 95.5 0.1 1.7e-27 95.1 0.1 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix PadR PF03551.14 AAZ37750.1 - 0.01 15.7 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family HTH_34 PF13601.6 AAZ37750.1 - 0.046 13.9 0.0 0.084 13.1 0.0 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain DUF3116 PF11313.8 AAZ37750.1 - 0.092 12.6 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3116) MarR PF01047.22 AAZ37750.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 MarR family DUF1971 PF09313.11 AAZ37750.1 - 0.12 12.4 0.4 0.45 10.6 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1971) Phage_GPD PF05954.11 AAZ37751.1 - 2.1e-46 158.6 0.2 1.9e-41 142.3 0.1 2.1 1 1 1 2 2 2 2 Phage late control gene D protein (GPD) Ala_racemase_N PF01168.20 AAZ37752.1 - 9.8e-33 113.6 0.1 1.2e-32 113.3 0.1 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Sigma70_r2 PF04542.14 AAZ37753.1 - 2.3e-17 62.5 0.3 5.4e-16 58.1 0.0 2.6 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 AAZ37753.1 - 2.4e-16 59.0 1.2 8.7e-16 57.2 0.3 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r1_2 PF00140.20 AAZ37753.1 - 1.4e-05 25.0 1.7 1.4e-05 25.0 0.1 1.8 2 0 0 2 2 2 1 Sigma-70 factor, region 1.2 UCR_14kD PF02271.16 AAZ37753.1 - 0.012 15.5 1.5 0.17 11.9 0.0 2.8 2 1 1 3 3 3 0 Ubiquinol-cytochrome C reductase complex 14kD subunit IF2_N PF04760.15 AAZ37753.1 - 0.054 13.3 0.3 2.1 8.2 0.1 2.7 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region ImpA_N PF06812.12 AAZ37753.1 - 0.057 13.5 0.9 0.13 12.4 0.9 1.6 1 0 0 1 1 1 0 ImpA, N-terminal, type VI secretion system Sigma70_r3 PF04539.16 AAZ37753.1 - 0.06 13.5 0.3 5.9 7.1 0.0 2.7 2 0 0 2 2 2 0 Sigma-70 region 3 HTH_25 PF13413.6 AAZ37753.1 - 0.098 12.5 0.5 0.66 9.9 0.2 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain SANT_DAMP1_like PF16282.5 AAZ37753.1 - 0.2 11.9 1.0 0.59 10.4 1.0 1.8 1 1 0 1 1 1 0 SANT/Myb-like domain of DAMP1 GntR PF00392.21 AAZ37753.1 - 1.6 8.4 3.8 1.2 8.9 0.1 2.5 3 0 0 3 3 3 0 Bacterial regulatory proteins, gntR family NMT1 PF09084.11 AAZ37754.1 - 6.1e-08 32.9 1.1 1.1e-07 32.0 0.9 1.5 1 1 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 AAZ37754.1 - 9.6e-05 22.2 4.0 0.00059 19.6 3.1 2.4 2 1 0 2 2 2 1 NMT1-like family SBP_bac_3 PF00497.20 AAZ37754.1 - 0.00022 20.7 0.4 0.00082 18.9 0.4 1.9 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 TPR_2 PF07719.17 AAZ37755.1 - 2.9e-06 27.0 5.4 0.26 11.5 0.0 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 AAZ37755.1 - 3.5e-05 23.4 0.8 0.0078 15.9 0.1 2.9 2 1 1 3 3 3 1 TPR repeat TPR_1 PF00515.28 AAZ37755.1 - 0.00014 21.5 1.2 0.77 9.7 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 AAZ37755.1 - 0.00056 20.1 5.5 0.65 10.5 0.2 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 AAZ37755.1 - 0.0018 18.9 7.9 0.55 10.9 0.6 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 AAZ37755.1 - 0.0024 18.3 13.6 0.0057 17.1 2.2 3.7 2 2 1 3 3 3 2 Tetratricopeptide repeat EST1_DNA_bind PF10373.9 AAZ37755.1 - 0.029 13.9 0.1 0.039 13.4 0.1 1.2 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain Clp_N PF02861.20 AAZ37755.1 - 0.062 13.4 0.6 5.9 7.1 0.2 2.6 2 0 0 2 2 2 0 Clp amino terminal domain, pathogenicity island component TPR_8 PF13181.6 AAZ37755.1 - 0.073 13.3 0.4 10 6.6 0.0 3.2 4 0 0 4 4 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 AAZ37755.1 - 0.087 13.1 0.9 0.19 12.0 0.9 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 AAZ37755.1 - 0.14 12.4 14.7 2.7 8.3 1.3 4.3 1 1 3 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 AAZ37755.1 - 0.32 10.7 4.9 1.2 8.8 0.9 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 AAZ37755.1 - 0.47 10.4 11.4 4.3 7.3 0.4 3.9 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 AAZ37755.1 - 1 10.2 15.5 9.9 7.1 4.0 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 AAZ37755.1 - 1.9 9.5 7.7 1.7 9.7 0.2 3.7 1 1 4 5 5 5 0 Tetratricopeptide repeat DUF4995 PF16386.5 AAZ37756.1 - 0.17 11.9 0.1 0.47 10.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF4870 PF09685.10 AAZ37757.1 - 1.8e-40 137.5 2.1 2e-40 137.3 2.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4870) DUF2207 PF09972.9 AAZ37757.1 - 0.28 9.9 1.3 0.3 9.8 1.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Glutaredoxin PF00462.24 AAZ37758.1 - 3.6e-20 72.0 0.1 4.2e-20 71.7 0.1 1.1 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 AAZ37758.1 - 0.00069 20.0 0.0 0.00079 19.8 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AAZ37758.1 - 0.0096 16.2 0.0 0.012 15.9 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF836 PF05768.14 AAZ37758.1 - 0.045 14.2 0.0 0.055 13.9 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 AAZ37758.1 - 0.067 13.7 0.3 0.095 13.2 0.3 1.4 1 1 0 1 1 1 0 Thioredoxin-like domain SH3BGR PF04908.15 AAZ37758.1 - 0.13 12.5 0.0 0.19 11.9 0.0 1.4 1 1 0 1 1 1 0 SH3-binding, glutamic acid-rich protein DSBA PF01323.20 AAZ37758.1 - 0.14 11.9 0.4 0.2 11.4 0.4 1.4 1 1 0 1 1 1 0 DSBA-like thioredoxin domain Bmp PF02608.14 AAZ37759.1 - 3.4e-43 147.7 0.0 4.4e-43 147.4 0.0 1.0 1 0 0 1 1 1 1 ABC transporter substrate-binding protein PnrA-like FCD PF07729.12 AAZ37760.1 - 6.7e-31 107.3 3.2 1.1e-30 106.6 3.2 1.4 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 AAZ37760.1 - 1.3e-16 60.0 0.2 2.7e-16 59.0 0.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_20 PF12840.7 AAZ37760.1 - 0.011 15.7 0.5 0.93 9.6 0.0 2.9 2 1 0 2 2 2 0 Helix-turn-helix domain MarR_2 PF12802.7 AAZ37760.1 - 0.015 15.2 2.9 0.42 10.5 0.1 2.8 3 0 0 3 3 3 0 MarR family TetR_C_11 PF16859.5 AAZ37760.1 - 0.04 14.2 3.5 0.21 11.9 0.8 3.0 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain TetR_C_7 PF14246.6 AAZ37760.1 - 0.069 13.2 0.4 0.36 10.9 0.3 2.2 1 1 0 1 1 1 0 AefR-like transcriptional repressor, C-terminal domain HTH_24 PF13412.6 AAZ37760.1 - 0.14 11.8 0.3 0.63 9.7 0.0 2.2 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding DUF3117 PF11314.8 AAZ37760.1 - 0.19 11.5 2.0 0.5 10.2 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3117) Ferritin PF00210.24 AAZ37761.1 - 3.2e-32 111.4 1.5 3.6e-32 111.2 1.5 1.0 1 0 0 1 1 1 1 Ferritin-like domain NLPC_P60 PF00877.19 AAZ37762.1 - 1.3e-27 95.9 0.0 2.1e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 NlpC/P60 family Amidase_5 PF05382.13 AAZ37762.1 - 0.0065 16.4 0.0 0.011 15.6 0.0 1.4 1 1 0 1 1 1 1 Bacteriophage peptidoglycan hydrolase Peptidase_C92 PF05708.12 AAZ37762.1 - 0.0086 16.2 0.0 2.8 8.0 0.0 2.7 1 1 1 2 2 2 2 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family DUF1175 PF06672.11 AAZ37762.1 - 0.063 12.9 0.0 1.1 8.8 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1175) Amidase_6 PF12671.7 AAZ37762.1 - 0.15 12.2 0.0 0.34 11.0 0.0 1.6 1 1 0 1 1 1 0 Putative amidase domain LRAT PF04970.13 AAZ37762.1 - 0.17 12.2 0.0 3.2 8.1 0.0 2.2 2 0 0 2 2 2 0 Lecithin retinol acyltransferase PilP PF04351.13 AAZ37763.1 - 1.2e-46 158.3 0.0 1.4e-46 158.1 0.0 1.0 1 0 0 1 1 1 1 Pilus assembly protein, PilP BPD_transp_1 PF00528.22 AAZ37764.1 - 3.9e-43 147.4 12.5 6.9e-43 146.5 12.5 1.4 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component Phage_integrase PF00589.22 AAZ37765.1 - 2.2e-23 82.9 0.4 3.9e-23 82.1 0.4 1.4 1 0 0 1 1 1 1 Phage integrase family Glutaredoxin PF00462.24 AAZ37766.1 - 8.9e-18 64.3 0.0 1.2e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 AAZ37766.1 - 0.14 12.5 0.0 0.22 12.0 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Flavin_Reduct PF01613.18 AAZ37768.1 - 9.8e-34 116.6 0.0 1.1e-33 116.5 0.0 1.0 1 0 0 1 1 1 1 Flavin reductase like domain Histidinol_dh PF00815.20 AAZ37769.1 - 1.2e-170 567.9 0.2 1.4e-170 567.8 0.2 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase PadR PF03551.14 AAZ37770.1 - 8.9e-18 64.0 0.0 1.6e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family CbtB PF09489.10 AAZ37770.1 - 0.0075 16.3 0.5 0.014 15.5 0.5 1.4 1 0 0 1 1 1 1 Probable cobalt transporter subunit (CbtB) DUF4364 PF14277.6 AAZ37770.1 - 0.08 12.7 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) Pyr_redox_2 PF07992.14 AAZ37771.1 - 1.3e-47 162.5 0.0 1.6e-47 162.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rbx_binding PF18113.1 AAZ37771.1 - 8.1e-26 89.6 0.0 1.7e-25 88.6 0.0 1.6 1 0 0 1 1 1 1 Rubredoxin binding C-terminal domain Pyr_redox PF00070.27 AAZ37771.1 - 7.7e-13 48.8 0.0 1.2e-09 38.6 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 AAZ37771.1 - 1.8e-06 27.3 0.1 0.043 12.9 0.0 3.2 3 0 0 3 3 3 2 Lycopene cyclase protein Amino_oxidase PF01593.24 AAZ37771.1 - 5.3e-05 22.7 0.0 0.00013 21.4 0.0 1.6 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.24 AAZ37771.1 - 9.9e-05 22.1 1.2 1.5 8.3 0.0 3.9 4 0 0 4 4 4 2 FAD dependent oxidoreductase ThiF PF00899.21 AAZ37771.1 - 0.007 15.8 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 ThiF family AlaDh_PNT_C PF01262.21 AAZ37771.1 - 0.016 14.5 0.1 1.9 7.7 0.0 2.6 2 1 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 AAZ37771.1 - 0.031 14.3 0.0 0.39 10.7 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.22 AAZ37771.1 - 0.034 13.2 0.1 2 7.4 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_7 PF13241.6 AAZ37771.1 - 0.046 14.2 0.0 0.41 11.1 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 AAZ37771.1 - 0.051 12.8 0.0 0.6 9.3 0.0 2.1 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 AAZ37771.1 - 0.097 12.5 0.0 0.62 9.9 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lipoprotein_18 PF06804.11 AAZ37772.1 - 2.1e-21 76.3 0.0 2.6e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 NlpB/DapX lipoprotein MerR_1 PF13411.6 AAZ37773.1 - 4.2e-22 78.0 0.1 6.4e-22 77.4 0.1 1.3 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 AAZ37773.1 - 6.5e-10 38.6 0.0 1.2e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 MerR family regulatory protein HTH_17 PF12728.7 AAZ37773.1 - 0.0099 16.0 0.0 0.022 14.9 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain IL28A PF15177.6 AAZ37774.1 - 0.058 13.2 2.5 0.054 13.3 0.5 1.9 1 1 1 2 2 2 0 Interleukin-28A AA_synth PF06684.11 AAZ37775.1 - 5.5e-69 231.2 0.4 6.3e-69 231.0 0.4 1.0 1 0 0 1 1 1 1 Amino acid synthesis LysM PF01476.20 AAZ37776.1 - 1.7e-36 124.0 2.4 1.7e-11 44.0 0.0 5.2 6 0 0 6 6 6 3 LysM domain SLT PF01464.20 AAZ37776.1 - 2.6e-25 88.4 0.0 7.6e-25 86.8 0.0 1.7 1 0 0 1 1 1 1 Transglycosylase SLT domain MLTD_N PF06474.12 AAZ37776.1 - 4.1e-16 58.9 5.8 1.8e-15 56.8 5.3 2.5 2 0 0 2 2 2 1 MltD lipid attachment motif OapA PF04225.12 AAZ37776.1 - 0.00031 20.8 1.4 0.61 10.2 0.3 3.3 2 1 1 3 3 3 2 Opacity-associated protein A LysM-like domain DUF3071 PF11268.8 AAZ37776.1 - 0.0049 16.9 0.2 4 7.5 0.1 3.4 3 1 0 3 3 3 1 Protein of unknown function (DUF3071) Formyl_trans_N PF00551.19 AAZ37777.1 - 9e-39 133.1 0.0 1.1e-38 132.7 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.25 AAZ37777.1 - 2.4e-05 24.0 0.0 8.3e-05 22.3 0.0 2.0 2 0 0 2 2 2 1 ACT domain Isochorismatase PF00857.20 AAZ37778.1 - 4.7e-33 114.8 0.0 5.4e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family DUF2325 PF10087.9 AAZ37778.1 - 0.052 13.7 0.0 0.16 12.1 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2325) OEP PF02321.18 AAZ37779.1 - 5.4e-42 143.7 37.6 3.8e-25 88.8 13.5 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein YkyA PF10368.9 AAZ37779.1 - 0.061 13.0 1.5 0.12 12.0 1.5 1.4 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Radical_SAM PF04055.21 AAZ37780.1 - 4.8e-19 69.3 0.0 8.1e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily HemN_C PF06969.16 AAZ37780.1 - 2.2e-10 40.4 0.0 6.6e-10 38.9 0.0 1.9 1 0 0 1 1 1 1 HemN C-terminal domain ImcF-related_N PF14331.6 AAZ37781.1 - 1.6e-70 237.5 2.5 1.6e-70 237.5 2.5 1.8 2 0 0 2 2 2 1 ImcF-related N-terminal domain OmpA PF00691.20 AAZ37781.1 - 4.4e-14 52.6 0.0 9.2e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 OmpA family IcmF-related PF06761.12 AAZ37781.1 - 7.6e-13 48.6 0.7 7.6e-13 48.6 0.7 2.2 3 0 0 3 3 3 1 Intracellular multiplication and human macrophage-killing MMR_HSR1 PF01926.23 AAZ37781.1 - 0.0012 18.9 0.0 0.0057 16.7 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase FUSC PF04632.12 AAZ37781.1 - 0.2 10.1 3.5 0.85 8.1 0.1 2.5 3 0 0 3 3 3 0 Fusaric acid resistance protein family DUF4131 PF13567.6 AAZ37781.1 - 0.42 10.3 3.9 3.9 7.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) ABC_export PF16962.5 AAZ37781.1 - 5.7 5.3 5.4 13 4.0 0.0 2.1 2 0 0 2 2 2 0 Putative ABC exporter BPD_transp_1 PF00528.22 AAZ37782.1 - 9.2e-25 87.4 11.4 1.1e-24 87.2 11.4 1.1 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component Ald_Xan_dh_C2 PF02738.18 AAZ37783.1 - 5.5e-121 404.7 0.1 8.1e-121 404.2 0.1 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 AAZ37783.1 - 2.5e-23 82.6 0.1 6.7e-23 81.1 0.1 1.8 2 0 0 2 2 2 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain PGM1_C PF18105.1 AAZ37783.1 - 0.17 11.5 1.6 7.5 6.2 0.1 3.1 3 0 0 3 3 3 0 PGM1 C-terminal domain EAL PF00563.20 AAZ37784.1 - 2.3e-63 213.9 0.0 4.1e-63 213.1 0.0 1.4 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AAZ37784.1 - 1.4e-40 138.7 0.0 3e-40 137.6 0.0 1.6 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS PF00989.25 AAZ37784.1 - 2.2e-11 43.7 0.0 5.9e-11 42.4 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AAZ37784.1 - 1.6e-07 31.5 0.0 3.8e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 AAZ37784.1 - 2.4e-07 31.0 0.0 3.6e-06 27.2 0.0 2.8 3 0 0 3 3 3 1 PAS fold PAS_8 PF13188.7 AAZ37784.1 - 1.1e-05 25.3 0.2 0.0054 16.7 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS_7 PF12860.7 AAZ37784.1 - 0.025 14.7 0.0 0.053 13.7 0.0 1.5 1 0 0 1 1 1 0 PAS fold MutS_V PF00488.21 AAZ37785.1 - 2.8e-85 285.1 0.0 5.4e-85 284.2 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.20 AAZ37785.1 - 2.5e-43 146.9 0.0 4.6e-43 146.1 0.0 1.4 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.18 AAZ37785.1 - 1.2e-39 136.5 4.2 2.4e-39 135.6 4.2 1.5 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.17 AAZ37785.1 - 1.7e-30 106.1 0.0 4.8e-30 104.6 0.0 1.8 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 AAZ37785.1 - 2.6e-29 101.4 0.0 9.7e-29 99.6 0.0 2.1 1 0 0 1 1 1 1 MutS family domain IV Aminotran_5 PF00266.19 AAZ37786.1 - 1.7e-133 445.1 0.0 2e-133 445.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V adh_short_C2 PF13561.6 AAZ37787.1 - 7e-69 231.9 0.1 7.9e-69 231.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAZ37787.1 - 1.1e-45 155.5 0.0 1.4e-45 155.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAZ37787.1 - 3.9e-13 49.7 0.1 6e-13 49.1 0.1 1.2 1 0 0 1 1 1 1 KR domain SBP_bac_3 PF00497.20 AAZ37789.1 - 1.3e-20 73.8 0.0 1.6e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Glycos_transf_1 PF00534.20 AAZ37790.1 - 3.6e-49 166.6 0.0 5.8e-27 94.3 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAZ37790.1 - 1.5e-36 125.8 0.0 1.2e-20 74.3 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AAZ37790.1 - 9.4e-08 32.4 0.0 2e-05 24.9 0.0 2.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAZ37790.1 - 7.6e-06 26.0 0.1 0.0056 16.7 0.0 2.9 2 1 0 2 2 2 2 Glycosyltransferase Family 4 GA-like PF17573.2 AAZ37790.1 - 0.092 12.7 0.0 0.4 10.6 0.0 2.1 2 0 0 2 2 2 0 GA-like domain LrgA PF03788.14 AAZ37791.1 - 8.7e-20 70.5 10.2 1.5e-19 69.8 10.2 1.4 1 0 0 1 1 1 1 LrgA family DUF4010 PF13194.6 AAZ37791.1 - 0.91 9.2 11.4 1.2 8.8 11.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4010) Glycos_transf_3 PF00591.21 AAZ37792.1 - 1.2e-99 333.1 1.6 1.9e-99 332.3 1.6 1.3 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 AAZ37792.1 - 3.3e-19 68.5 0.5 3.3e-19 68.5 0.5 1.9 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain RNase_T PF00929.24 AAZ37793.1 - 6e-11 43.2 0.0 7.5e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 AAZ37793.1 - 0.00013 22.0 0.1 0.0018 18.2 0.1 2.1 1 1 0 1 1 1 1 3' exoribonuclease, RNase T-like TonB_dep_Rec PF00593.24 AAZ37794.1 - 2.7e-65 222.1 22.3 2.7e-65 222.1 22.3 1.5 2 0 0 2 2 2 1 TonB dependent receptor Plug PF07715.15 AAZ37794.1 - 1.4e-20 73.8 0.4 3.9e-20 72.4 0.4 1.8 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain GntP_permease PF02447.16 AAZ37795.1 - 6.9e-122 407.3 44.4 9.2e-122 406.9 44.4 1.0 1 0 0 1 1 1 1 GntP family permease CitMHS PF03600.16 AAZ37795.1 - 6.4e-20 71.5 38.1 6.4e-20 71.5 38.1 1.8 2 0 0 2 2 2 1 Citrate transporter DctM PF06808.12 AAZ37795.1 - 0.29 9.9 45.1 0.085 11.7 17.5 2.9 1 1 2 3 3 3 0 Tripartite ATP-independent periplasmic transporter, DctM component Aldedh PF00171.22 AAZ37796.1 - 3e-119 398.6 0.0 3.6e-119 398.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ammonium_transp PF00909.21 AAZ37797.1 - 1.5e-109 366.4 40.5 1.7e-109 366.2 40.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF4006 PF13179.6 AAZ37797.1 - 1 9.3 3.6 3 7.8 0.4 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF4006) LptF_LptG PF03739.14 AAZ37798.1 - 4.9e-69 232.8 4.6 5.6e-69 232.7 4.6 1.0 1 0 0 1 1 1 1 Lipopolysaccharide export system permease LptF/LptG Pirin PF02678.16 AAZ37799.1 - 7.5e-28 96.7 0.1 1.5e-27 95.7 0.1 1.5 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.11 AAZ37799.1 - 0.0031 17.2 0.3 0.013 15.2 0.2 2.1 2 0 0 2 2 2 1 Cupin domain RES PF08808.11 AAZ37800.1 - 2.5e-26 92.5 0.1 2.9e-26 92.3 0.1 1.0 1 0 0 1 1 1 1 RES domain Transposase_mut PF00872.18 AAZ37801.1 - 5.4e-116 387.6 0.0 6.7e-116 387.3 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ37801.1 - 7.7e-05 23.0 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain DUF4844 PF16133.5 AAZ37801.1 - 0.23 12.0 0.0 0.55 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) HAGH_C PF16123.5 AAZ37802.1 - 3.2e-26 91.6 0.4 4.8e-26 91.1 0.4 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 AAZ37802.1 - 6.8e-16 58.8 7.0 1.5e-15 57.7 7.0 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AAZ37802.1 - 0.011 15.3 1.8 0.018 14.5 1.8 1.6 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 AAZ37802.1 - 0.015 15.2 0.1 0.027 14.4 0.1 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Lactamase_B_5 PF14597.6 AAZ37802.1 - 0.015 14.8 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily PCuAC PF04314.13 AAZ37803.1 - 4.1e-34 116.7 0.1 4.9e-34 116.4 0.1 1.1 1 0 0 1 1 1 1 Copper chaperone PCu(A)C PAS_6 PF08348.11 AAZ37804.1 - 0.0068 16.3 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 YheO-like PAS domain DAO PF01266.24 AAZ37806.1 - 6.3e-54 183.9 1.9 7.3e-54 183.7 1.9 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AAZ37806.1 - 6.3e-07 29.5 0.2 6.3e-07 29.5 0.2 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 AAZ37806.1 - 8.4e-06 25.2 0.1 1.6e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 AAZ37806.1 - 8.5e-06 25.1 6.6 0.00013 21.2 6.6 2.1 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 AAZ37806.1 - 0.00021 20.8 2.0 0.00049 19.6 1.6 2.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 AAZ37806.1 - 0.0026 17.1 0.6 0.017 14.4 0.8 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 AAZ37806.1 - 0.0027 17.0 0.0 0.0046 16.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AAZ37806.1 - 0.015 14.5 0.9 0.024 13.9 0.9 1.3 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 AAZ37806.1 - 0.044 12.6 1.1 0.074 11.9 1.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.6 AAZ37806.1 - 0.075 13.0 0.1 0.17 11.9 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding MCRA PF06100.11 AAZ37806.1 - 0.14 10.9 0.1 0.2 10.4 0.1 1.2 1 0 0 1 1 1 0 MCRA family DAO PF01266.24 AAZ37807.1 - 2.3e-51 175.4 1.5 2.7e-51 175.2 1.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 AAZ37807.1 - 2.1e-06 27.2 0.2 4.1e-06 26.2 0.2 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 AAZ37807.1 - 4.8e-06 26.1 0.6 1.1e-05 24.9 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 AAZ37807.1 - 4.6e-05 23.6 1.8 0.00019 21.6 0.3 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 AAZ37807.1 - 0.00012 21.3 0.3 0.00024 20.3 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 AAZ37807.1 - 0.0007 18.9 0.1 0.0012 18.1 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAZ37807.1 - 0.00085 19.8 0.3 0.0047 17.5 0.2 2.3 2 1 1 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 AAZ37807.1 - 0.007 15.7 0.1 0.11 11.8 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase UDPG_MGDP_dh_N PF03721.14 AAZ37807.1 - 0.0086 15.7 0.2 0.015 14.9 0.2 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.14 AAZ37807.1 - 0.019 13.7 0.6 0.027 13.2 0.1 1.5 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.6 AAZ37807.1 - 0.025 13.8 0.3 0.76 9.0 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 AAZ37807.1 - 0.042 14.3 0.1 0.19 12.2 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding GIDA PF01134.22 AAZ37807.1 - 0.1 11.7 0.2 0.24 10.4 0.1 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 AAZ37807.1 - 0.11 12.4 0.2 0.23 11.3 0.1 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AAA_33 PF13671.6 AAZ37809.1 - 2.1e-24 86.3 0.0 2.4e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AAZ37809.1 - 1.3e-06 28.9 0.1 4.3e-06 27.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 AAZ37809.1 - 2.3e-05 24.4 0.0 0.088 12.7 0.0 2.1 2 0 0 2 2 2 2 Deoxynucleoside kinase Zeta_toxin PF06414.12 AAZ37809.1 - 0.0098 15.2 0.0 0.014 14.7 0.0 1.3 1 1 0 1 1 1 1 Zeta toxin AAA_25 PF13481.6 AAZ37809.1 - 0.011 15.3 5.8 1.6 8.3 5.8 2.6 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 AAZ37809.1 - 0.015 15.7 0.0 0.05 14.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AAZ37809.1 - 0.019 14.7 0.1 0.032 14.0 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain CoaE PF01121.20 AAZ37809.1 - 0.019 14.7 0.1 0.12 12.0 0.0 2.0 1 1 1 2 2 2 0 Dephospho-CoA kinase SKI PF01202.22 AAZ37809.1 - 0.043 14.0 0.0 0.36 10.9 0.0 2.3 1 1 0 1 1 1 0 Shikimate kinase CPT PF07931.12 AAZ37809.1 - 0.064 13.1 0.3 0.25 11.2 0.3 1.8 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein APS_kinase PF01583.20 AAZ37809.1 - 0.068 13.1 0.0 0.12 12.2 0.0 1.3 1 1 0 1 1 1 0 Adenylylsulphate kinase Cytidylate_kin PF02224.18 AAZ37809.1 - 0.079 12.7 0.2 1.4 8.6 0.1 2.1 1 1 1 2 2 2 0 Cytidylate kinase Thymidylate_kin PF02223.17 AAZ37809.1 - 0.11 12.2 0.3 0.91 9.2 0.3 2.3 1 1 0 1 1 1 0 Thymidylate kinase Ploopntkinase1 PF18748.1 AAZ37809.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 KTI12 PF08433.10 AAZ37809.1 - 0.14 11.6 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ADK PF00406.22 AAZ37809.1 - 0.14 12.2 0.0 0.62 10.2 0.0 1.8 1 1 0 1 1 1 0 Adenylate kinase AAA_24 PF13479.6 AAZ37809.1 - 0.18 11.5 0.0 0.21 11.3 0.0 1.3 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 AAZ37809.1 - 0.2 10.8 0.0 0.31 10.1 0.0 1.3 1 1 0 1 1 1 0 G-protein alpha subunit ABC_tran PF00005.27 AAZ37809.1 - 0.22 12.1 0.0 0.29 11.6 0.0 1.4 1 1 0 1 1 1 0 ABC transporter TetR_C_13 PF16925.5 AAZ37810.1 - 1.6e-46 156.9 0.0 2.3e-46 156.4 0.0 1.2 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 AAZ37810.1 - 1.2e-10 41.0 0.1 2.1e-10 40.2 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 AAZ37810.1 - 0.048 14.0 0.1 0.12 12.7 0.0 1.7 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain IucA_IucC PF04183.12 AAZ37811.1 - 1e-54 185.6 0.2 3e-54 184.1 0.0 1.8 2 0 0 2 2 2 1 IucA / IucC family FhuF PF06276.12 AAZ37811.1 - 3.3e-16 60.1 0.2 1.3e-15 58.2 0.2 2.0 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter ATP_synth_reg PF14960.6 AAZ37812.1 - 3.5 7.2 5.8 3.4 7.2 1.8 2.3 2 0 0 2 2 2 0 ATP synthase regulation AAA_32 PF13654.6 AAZ37813.1 - 9.5e-166 552.6 0.0 1.1e-165 552.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain Lon_C PF05362.13 AAZ37813.1 - 1.1e-06 28.3 0.0 2.6e-06 27.1 0.0 1.7 1 1 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA_5 PF07728.14 AAZ37813.1 - 0.0051 16.8 0.0 4.1 7.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Transp_cyt_pur PF02133.15 AAZ37814.1 - 0.0022 16.9 3.2 0.0088 14.9 0.1 2.0 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin LysR_substrate PF03466.20 AAZ37816.1 - 4.3e-34 117.7 5.0 5.4e-34 117.4 5.0 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ37816.1 - 1.7e-15 56.7 0.0 3.7e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family ABC-3 PF00950.17 AAZ37817.1 - 9.8e-51 172.7 30.5 1.1e-50 172.5 30.5 1.0 1 0 0 1 1 1 1 ABC 3 transport family FecCD PF01032.18 AAZ37817.1 - 2.6e-08 33.3 32.0 2.6e-08 33.3 32.0 1.4 1 1 0 1 1 1 1 FecCD transport family CBP_BcsG PF11658.8 AAZ37817.1 - 1.1 7.6 7.6 1.5 7.2 7.6 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG PDR_assoc PF08370.11 AAZ37817.1 - 4.5 7.1 6.7 6.8 6.5 0.5 3.5 3 0 0 3 3 3 0 Plant PDR ABC transporter associated DUF2407_C PF13373.6 AAZ37817.1 - 9.8 6.4 7.2 4.5 7.4 1.6 2.5 2 0 0 2 2 2 0 DUF2407 C-terminal domain DUF3188 PF11384.8 AAZ37818.1 - 0.085 12.6 2.6 2.1 8.1 2.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) Response_reg PF00072.24 AAZ37819.1 - 3.9e-27 94.6 0.1 5.8e-27 94.1 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AAZ37819.1 - 1.1e-13 50.5 0.1 3.6e-13 48.8 0.0 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family FGGY_N PF00370.21 AAZ37820.1 - 5e-86 288.3 0.5 8.6e-86 287.5 0.5 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 AAZ37820.1 - 2e-63 213.7 0.1 1.7e-62 210.7 0.2 2.0 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain LYTB PF02401.18 AAZ37821.1 - 2.7e-92 308.7 0.0 3.1e-92 308.6 0.0 1.0 1 0 0 1 1 1 1 LytB protein AMNp_N PF10423.9 AAZ37822.1 - 2.4e-49 167.0 0.2 1.5e-48 164.4 0.2 2.0 2 0 0 2 2 2 1 Bacterial AMP nucleoside phosphorylase N-terminus PNP_UDP_1 PF01048.20 AAZ37822.1 - 6.6e-16 58.3 0.0 1.1e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily PGM_PMM_I PF02878.16 AAZ37823.1 - 2.3e-43 147.2 0.0 4.9e-43 146.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 AAZ37823.1 - 5.9e-29 100.6 0.0 1e-28 99.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 AAZ37823.1 - 1e-19 71.0 0.1 2.2e-19 70.0 0.1 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 AAZ37823.1 - 2.8e-12 46.6 0.1 8.1e-12 45.2 0.1 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF384 PF04064.13 AAZ37823.1 - 0.15 11.9 0.1 2.3 8.1 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF384) ATP-synt PF00231.19 AAZ37824.1 - 1.3e-96 323.6 0.2 1.5e-96 323.4 0.2 1.0 1 0 0 1 1 1 1 ATP synthase DUF432 PF04254.13 AAZ37824.1 - 0.028 14.6 0.0 0.068 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF432) NAD_binding_4 PF07993.12 AAZ37825.1 - 2.7e-26 92.3 0.0 1.5e-12 47.2 0.1 2.6 1 1 1 2 2 2 2 Male sterility protein Epimerase PF01370.21 AAZ37825.1 - 6.5e-06 25.8 0.0 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 AAZ37825.1 - 4.9e-05 23.3 0.2 7.7e-05 22.7 0.2 1.2 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 AAZ37825.1 - 6.6e-05 22.0 0.0 0.00018 20.6 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 AAZ37825.1 - 0.0071 15.5 0.1 0.022 13.8 0.1 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 AAZ37825.1 - 0.01 15.7 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 AAZ37825.1 - 0.014 14.8 0.0 0.021 14.2 0.0 1.3 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 AAZ37825.1 - 0.037 13.2 0.0 0.051 12.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.25 AAZ37825.1 - 0.053 13.0 0.1 0.1 12.1 0.1 1.6 1 1 0 1 1 1 0 short chain dehydrogenase DUF3290 PF11694.8 AAZ37826.1 - 0.046 13.7 0.1 0.051 13.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) ATPgrasp_N PF18130.1 AAZ37826.1 - 0.058 14.0 0.0 0.083 13.5 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp N-terminal domain BPD_transp_1 PF00528.22 AAZ37827.1 - 8.5e-14 51.7 7.9 8.5e-14 51.7 7.9 1.9 1 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Cytidylate_kin PF02224.18 AAZ37828.1 - 6.3e-77 258.1 0.0 7.1e-77 257.9 0.0 1.0 1 0 0 1 1 1 1 Cytidylate kinase Cytidylate_kin2 PF13189.6 AAZ37828.1 - 1.5e-07 31.7 0.1 9e-07 29.2 0.1 2.2 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_18 PF13238.6 AAZ37828.1 - 7.6e-06 26.5 0.1 0.00014 22.4 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AAZ37828.1 - 2.5e-05 24.5 0.1 4.3e-05 23.7 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 AAZ37828.1 - 0.00039 20.9 0.2 0.0075 16.7 0.1 2.4 1 1 0 1 1 1 1 AAA domain ADK PF00406.22 AAZ37828.1 - 0.0054 16.8 0.0 0.0091 16.1 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase SKI PF01202.22 AAZ37828.1 - 0.0054 16.9 0.3 0.12 12.4 0.1 2.6 3 0 0 3 3 3 1 Shikimate kinase AAA_22 PF13401.6 AAZ37828.1 - 0.023 15.0 0.1 0.076 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain dNK PF01712.19 AAZ37828.1 - 0.064 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Deoxynucleoside kinase MutL_C PF08676.11 AAZ37829.1 - 1.9e-50 170.5 0.5 5e-50 169.1 0.5 1.8 2 0 0 2 2 2 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 AAZ37829.1 - 1.5e-39 134.3 0.0 2.4e-39 133.7 0.0 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 AAZ37829.1 - 5.2e-10 39.3 0.0 8.6e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 AAZ37829.1 - 4.8e-05 23.8 0.0 0.00011 22.7 0.0 1.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_22 PF13401.6 AAZ37830.1 - 3e-05 24.3 0.1 0.11 12.7 0.0 2.8 3 0 0 3 3 3 2 AAA domain ABC_tran PF00005.27 AAZ37830.1 - 0.00045 20.7 0.1 2.7 8.5 0.0 3.2 3 0 0 3 3 3 2 ABC transporter AAA_30 PF13604.6 AAZ37830.1 - 0.00046 20.0 0.3 0.72 9.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 AAZ37830.1 - 0.004 17.7 0.1 0.12 13.0 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 AAZ37830.1 - 0.0067 16.2 0.0 2.2 8.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain MobB PF03205.14 AAZ37830.1 - 0.0086 16.0 0.0 0.36 10.7 0.0 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.6 AAZ37830.1 - 0.013 15.3 0.7 2.9 7.7 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain SRP54 PF00448.22 AAZ37830.1 - 0.017 14.7 0.6 1.5 8.4 0.1 2.4 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain MeaB PF03308.16 AAZ37830.1 - 0.024 13.6 0.6 0.32 9.9 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PEPCK_ATP PF01293.20 AAZ37830.1 - 0.045 12.4 0.1 0.067 11.8 0.1 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase ATP_bind_1 PF03029.17 AAZ37830.1 - 0.048 13.4 0.3 0.43 10.3 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 AAZ37830.1 - 0.06 13.7 0.9 2.7 8.4 0.1 3.2 3 1 0 3 3 3 0 AAA ATPase domain AAA_33 PF13671.6 AAZ37830.1 - 0.083 13.1 0.4 16 5.6 0.0 2.6 2 1 0 2 2 2 0 AAA domain PRK PF00485.18 AAZ37830.1 - 0.099 12.4 0.0 0.66 9.7 0.0 2.1 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family RsgA_GTPase PF03193.16 AAZ37830.1 - 0.11 12.4 0.1 4.7 7.1 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Zeta_toxin PF06414.12 AAZ37830.1 - 0.15 11.4 0.0 7.3 5.8 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin Bac_luciferase PF00296.20 AAZ37831.1 - 2.5e-51 175.0 0.2 3.3e-51 174.6 0.2 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Sulfatase PF00884.23 AAZ37832.1 - 6.5e-57 193.3 0.0 7.9e-57 193.0 0.0 1.1 1 0 0 1 1 1 1 Sulfatase EptA_B_N PF08019.12 AAZ37832.1 - 6.1e-50 169.1 6.5 8.9e-50 168.5 6.5 1.2 1 0 0 1 1 1 1 Phosphoethanolamine transferase EptA/EptB Phosphodiest PF01663.22 AAZ37832.1 - 0.094 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase MCPsignal PF00015.21 AAZ37833.1 - 6.9e-47 159.4 46.4 1.4e-45 155.2 22.6 4.9 3 1 2 5 5 5 3 Methyl-accepting chemotaxis protein (MCP) signalling domain HBM PF16591.5 AAZ37833.1 - 6e-20 71.7 9.9 6e-20 71.7 9.9 3.3 3 0 0 3 3 3 2 Helical bimodular sensor domain HAMP PF00672.25 AAZ37833.1 - 2.1e-12 47.2 26.5 3.6e-10 40.1 1.2 7.1 8 0 0 8 8 7 2 HAMP domain PhageMin_Tail PF10145.9 AAZ37833.1 - 0.0007 19.5 11.6 0.0007 19.5 11.6 5.0 3 1 1 5 5 5 2 Phage-related minor tail protein 4HB_MCP_1 PF12729.7 AAZ37833.1 - 0.0031 17.1 2.5 0.0031 17.1 2.5 5.8 4 2 1 5 5 5 1 Four helix bundle sensory module for signal transduction Syntaxin_2 PF14523.6 AAZ37833.1 - 0.0049 17.2 22.9 0.6 10.5 1.2 6.0 4 1 0 5 5 5 2 Syntaxin-like protein Spore_III_AB PF09548.10 AAZ37833.1 - 0.11 12.6 13.9 0.25 11.4 0.3 4.1 4 1 0 4 4 4 0 Stage III sporulation protein AB (spore_III_AB) FlaC_arch PF05377.11 AAZ37833.1 - 0.17 12.3 7.1 11 6.5 0.0 5.4 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) DUF948 PF06103.11 AAZ37833.1 - 0.21 11.9 34.6 0.68 10.2 3.3 7.0 3 2 4 7 7 7 0 Bacterial protein of unknown function (DUF948) DUF4064 PF13273.6 AAZ37833.1 - 0.55 10.5 5.9 1.9 8.8 0.8 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) BLOC1_2 PF10046.9 AAZ37833.1 - 0.56 10.5 20.9 16 5.9 0.1 5.8 4 2 0 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FH2 PF02181.23 AAZ37833.1 - 1.1 8.3 6.3 0.42 9.7 1.0 2.3 2 0 0 2 2 2 0 Formin Homology 2 Domain DUF4200 PF13863.6 AAZ37833.1 - 2.8 8.4 12.1 2.9 8.3 1.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) Syntaxin-6_N PF09177.11 AAZ37833.1 - 5.8 7.5 15.6 0.73 10.4 1.3 4.5 4 2 1 5 5 5 0 Syntaxin 6, N-terminal YiiD_C PF09500.10 AAZ37834.1 - 1.4e-48 164.4 0.0 1.6e-48 164.2 0.0 1.0 1 0 0 1 1 1 1 Putative thioesterase (yiiD_Cterm) Hydrolase_like PF13242.6 AAZ37835.1 - 2.5e-08 33.9 0.1 4.8e-08 33.0 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 AAZ37835.1 - 4.2e-07 30.2 0.0 5.8e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAZ37835.1 - 0.00036 20.9 0.0 0.00047 20.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF442 PF04273.13 AAZ37835.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative phosphatase (DUF442) Dioxygenase_C PF00775.21 AAZ37836.1 - 2.3e-17 63.0 0.1 2.6e-16 59.6 0.1 2.0 1 1 0 1 1 1 1 Dioxygenase NMT1 PF09084.11 AAZ37837.1 - 9.8e-14 51.8 0.0 1.3e-13 51.4 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 AAZ37837.1 - 1.1e-12 48.2 0.0 2.2e-12 47.2 0.0 1.5 1 1 0 1 1 1 1 NMT1-like family SBP_bac_3 PF00497.20 AAZ37837.1 - 4.4e-10 39.4 0.0 7e-08 32.2 0.0 2.1 2 0 0 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 OpuAC PF04069.12 AAZ37837.1 - 1.8e-07 31.0 0.0 2.6e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system NMT1_3 PF16868.5 AAZ37837.1 - 2.5e-07 30.4 0.0 1.2e-06 28.2 0.0 1.8 2 0 0 2 2 2 1 NMT1-like family Phosphonate-bd PF12974.7 AAZ37837.1 - 1.8e-05 24.5 0.0 2.2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein Isochorismatase PF00857.20 AAZ37838.1 - 1.5e-39 136.0 1.9 2.2e-39 135.4 1.9 1.3 1 0 0 1 1 1 1 Isochorismatase family RNase_HII PF01351.18 AAZ37839.1 - 1.9e-37 129.1 0.0 2.2e-37 128.9 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease HII DUF2345 PF10106.9 AAZ37840.1 - 1.3e-52 177.7 6.9 2.6e-52 176.7 6.9 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2345) DUF3540 PF12059.8 AAZ37840.1 - 0.0027 17.6 1.4 0.061 13.1 0.3 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3540) Sarcoglycan_1 PF04790.13 AAZ37840.1 - 0.0052 16.2 1.2 0.014 14.7 1.2 1.5 1 1 0 1 1 1 1 Sarcoglycan complex subunit protein Fil_haemagg_2 PF13332.6 AAZ37840.1 - 0.0066 16.6 2.8 0.0066 16.6 2.8 2.9 1 1 1 2 2 2 1 Hemagglutinin repeat Cthe_2159 PF14262.6 AAZ37840.1 - 0.011 15.1 2.1 0.011 15.1 2.1 1.7 1 1 0 1 1 1 0 Carbohydrate-binding domain-containing protein Cthe_2159 ORF_2_N PF18492.1 AAZ37840.1 - 0.059 13.6 0.6 0.13 12.4 0.6 1.6 1 0 0 1 1 1 0 Open reading frame 2 N-terminal domain Transposase_mut PF00872.18 AAZ37841.1 - 1.5e-117 392.7 0.0 1.9e-117 392.3 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ37841.1 - 7.7e-05 23.0 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain DUF4844 PF16133.5 AAZ37841.1 - 0.23 12.0 0.0 0.55 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) Alginate_exp PF13372.6 AAZ37842.1 - 2e-121 405.5 14.9 2.3e-121 405.3 14.9 1.0 1 0 0 1 1 1 1 Alginate export OMP_b-brl PF13505.6 AAZ37842.1 - 0.0056 16.8 1.9 0.0056 16.8 1.9 2.2 2 0 0 2 2 2 1 Outer membrane protein beta-barrel domain LamB PF02264.15 AAZ37843.1 - 3.3e-101 339.9 11.7 4e-101 339.7 11.7 1.1 1 0 0 1 1 1 1 LamB porin Sugarporin_N PF11471.8 AAZ37843.1 - 5.5e-06 26.2 13.5 0.00014 21.7 8.6 2.3 2 0 0 2 2 2 2 Maltoporin periplasmic N-terminal extension Tropomyosin PF00261.20 AAZ37843.1 - 0.052 12.9 1.8 0.088 12.2 1.8 1.2 1 0 0 1 1 1 0 Tropomyosin FUSC PF04632.12 AAZ37843.1 - 0.78 8.2 8.1 0.99 7.9 8.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family ABC_tran_CTD PF16326.5 AAZ37843.1 - 1.1 9.6 8.0 18 5.6 7.1 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain TolA_bind_tri PF16331.5 AAZ37843.1 - 2.9 8.0 5.7 6.6 6.9 2.8 2.4 2 0 0 2 2 2 0 TolA binding protein trimerisation Peptidase_M50 PF02163.22 AAZ37844.1 - 5.1e-83 278.2 0.0 6.1e-83 277.9 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M50 PDZ_6 PF17820.1 AAZ37844.1 - 7.4e-19 67.4 3.6 4.7e-10 39.2 0.1 2.4 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 AAZ37844.1 - 4.1e-14 52.7 0.1 9.4e-07 29.1 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 AAZ37844.1 - 5e-14 52.4 0.0 7.3e-09 35.8 0.0 2.4 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 AAZ37844.1 - 1.2e-05 25.2 1.0 0.17 11.9 0.0 2.9 3 0 0 3 3 3 2 Tricorn protease PDZ domain GRASP55_65 PF04495.14 AAZ37844.1 - 0.048 14.0 0.0 0.35 11.2 0.0 2.2 2 0 0 2 2 2 0 GRASP55/65 PDZ-like domain PDZ_4 PF17816.1 AAZ37844.1 - 0.068 13.6 0.0 1.6 9.1 0.0 2.4 2 0 0 2 2 2 0 PDZ domain DUF1654 PF07867.11 AAZ37844.1 - 0.14 11.9 1.0 2.1 8.1 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1654) Peptidase_M50B PF13398.6 AAZ37844.1 - 0.6 9.7 5.1 0.95 9.1 0.1 2.8 3 0 0 3 3 3 0 Peptidase M50B-like DUF4145 PF13643.6 AAZ37845.1 - 7.3e-05 22.8 0.1 0.00012 22.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4145) DUF808 PF05661.12 AAZ37846.1 - 7.2e-113 376.6 17.1 8.7e-113 376.4 17.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF808) Radical_SAM PF04055.21 AAZ37847.1 - 1.7e-17 64.3 0.0 3.2e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 AAZ37847.1 - 0.0038 17.3 0.0 0.012 15.7 0.0 1.8 1 1 0 1 1 1 1 4Fe-4S single cluster domain Ferric_reduct PF01794.19 AAZ37848.1 - 4.6e-15 55.8 7.7 4.6e-15 55.8 7.7 2.2 3 0 0 3 3 3 1 Ferric reductase like transmembrane component Formyl_trans_N PF00551.19 AAZ37849.1 - 1.3e-59 200.9 0.0 1.5e-59 200.7 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase PALP PF00291.25 AAZ37849.1 - 0.048 13.1 0.1 0.12 11.8 0.0 1.6 1 1 1 2 2 2 0 Pyridoxal-phosphate dependent enzyme UPF0175 PF03683.13 AAZ37849.1 - 0.064 13.0 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) Isochorismatase PF00857.20 AAZ37850.1 - 7.4e-42 143.5 0.0 8.7e-42 143.3 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family Ferritin PF00210.24 AAZ37851.1 - 3e-28 98.5 1.8 3.5e-28 98.3 1.8 1.1 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 AAZ37851.1 - 1.9e-07 31.5 3.2 3.7e-07 30.6 3.2 1.5 1 1 0 1 1 1 1 Rubrerythrin DUF2383 PF09537.10 AAZ37851.1 - 0.00016 22.0 0.7 0.0026 18.1 0.2 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF2383) COQ7 PF03232.13 AAZ37851.1 - 0.00079 19.2 0.2 0.21 11.4 0.0 2.2 2 0 0 2 2 2 2 Ubiquinone biosynthesis protein COQ7 Ferritin_2 PF13668.6 AAZ37851.1 - 0.0028 17.8 1.2 0.24 11.6 0.0 2.2 1 1 0 2 2 2 2 Ferritin-like domain DUF455 PF04305.14 AAZ37851.1 - 0.069 12.7 0.3 0.083 12.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF455) PRAI PF00697.22 AAZ37852.1 - 3.6e-48 163.9 0.0 4.1e-48 163.8 0.0 1.0 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Response_reg PF00072.24 AAZ37853.1 - 5.6e-20 71.6 0.0 8.7e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain HTH_8 PF02954.19 AAZ37853.1 - 1.1e-11 44.2 1.4 2.2e-11 43.3 0.4 1.9 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family HTH_30 PF13556.6 AAZ37853.1 - 1.2e-06 28.2 0.9 2.7e-06 27.1 0.9 1.6 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_28 PF13518.6 AAZ37853.1 - 0.0042 17.2 0.2 0.0085 16.2 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AAZ37853.1 - 0.079 12.8 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 Homeodomain-like domain DUF3313 PF11769.8 AAZ37854.1 - 2.8e-38 131.6 0.0 3.2e-38 131.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3313) T6SS_HCP PF05638.12 AAZ37855.1 - 1.1e-38 132.5 0.0 1.4e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 Type VI secretion system effector, Hcp Acetyltransf_1 PF00583.25 AAZ37856.1 - 4.2e-12 46.3 0.0 5.5e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AAZ37856.1 - 4.5e-11 42.8 0.0 7e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAZ37856.1 - 1.4e-08 35.0 0.0 2.2e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAZ37856.1 - 0.043 13.8 0.0 0.086 12.8 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_4 PF13420.7 AAZ37856.1 - 0.15 12.2 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF748 PF05359.11 AAZ37857.1 - 9.7e-11 42.1 0.1 1.8e-10 41.2 0.1 1.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF748) PG_binding_4 PF12229.8 AAZ37857.1 - 0.058 13.7 0.2 0.22 11.8 0.1 1.9 2 0 0 2 2 2 0 Putative peptidoglycan binding domain HTH_20 PF12840.7 AAZ37858.1 - 3e-09 36.8 0.0 5.1e-09 36.1 0.0 1.4 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 AAZ37858.1 - 1.3e-05 24.9 0.6 3.1e-05 23.8 0.5 1.6 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_IclR PF09339.10 AAZ37858.1 - 0.035 13.9 0.1 0.06 13.2 0.1 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain MarR_2 PF12802.7 AAZ37858.1 - 0.045 13.6 0.3 0.059 13.3 0.3 1.4 1 1 0 1 1 1 0 MarR family MarR PF01047.22 AAZ37858.1 - 0.088 12.8 0.0 0.24 11.4 0.0 1.7 2 0 0 2 2 2 0 MarR family Copper-bind PF00127.20 AAZ37861.1 - 1.8e-31 108.5 0.3 2.1e-31 108.3 0.3 1.0 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 AAZ37861.1 - 0.061 13.4 0.2 0.32 11.1 0.2 2.1 1 1 0 1 1 1 0 Cupredoxin-like domain SBP_bac_11 PF13531.6 AAZ37862.1 - 6.5e-44 150.4 6.8 7.7e-44 150.1 6.8 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AAZ37862.1 - 2e-09 37.8 10.2 0.00015 21.9 4.4 2.1 1 1 1 2 2 2 2 Bacterial extracellular solute-binding protein SpoU_methylase PF00588.19 AAZ37863.1 - 1.2e-33 116.3 0.0 1.7e-33 115.7 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family ETF PF01012.21 AAZ37863.1 - 0.094 12.6 0.9 0.13 12.1 0.1 1.7 2 1 1 3 3 3 0 Electron transfer flavoprotein domain MFS_1 PF07690.16 AAZ37864.1 - 8.4e-24 84.1 84.7 4.3e-19 68.6 44.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_68 PF02435.16 AAZ37865.1 - 2.4e-171 570.3 0.0 2.7e-171 570.1 0.0 1.0 1 0 0 1 1 1 1 Levansucrase/Invertase Glyco_hydro_43 PF04616.14 AAZ37865.1 - 0.0013 18.1 0.1 0.0093 15.3 0.1 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 AAZ37865.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain CxxCxxCC PF03692.15 AAZ37866.1 - 1.5e-08 35.2 0.0 1.6e-08 35.1 0.0 1.1 1 0 0 1 1 1 1 Putative zinc- or iron-chelating domain Polysacc_deac_1 PF01522.21 AAZ37867.1 - 3.9e-18 65.5 0.0 7e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 AAZ37867.1 - 0.056 13.1 0.0 0.083 12.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) RuvC PF02075.17 AAZ37868.1 - 5.1e-63 211.4 0.8 5.9e-63 211.2 0.8 1.0 1 0 0 1 1 1 1 Crossover junction endodeoxyribonuclease RuvC DUF3882 PF07066.11 AAZ37868.1 - 0.099 12.7 0.0 0.11 12.6 0.0 1.2 1 1 0 1 1 1 0 Lactococcus phage M3 protein SRP54 PF00448.22 AAZ37869.1 - 4.9e-73 245.0 1.9 8.4e-73 244.2 1.9 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 AAZ37869.1 - 3e-32 111.2 3.2 3e-32 111.2 3.2 3.0 4 0 0 4 4 2 1 Signal peptide binding domain SRP54_N PF02881.19 AAZ37869.1 - 2.4e-21 75.7 0.7 2.4e-21 75.7 0.7 2.7 3 0 0 3 3 3 1 SRP54-type protein, helical bundle domain CbiA PF01656.23 AAZ37869.1 - 3.9e-07 30.2 0.4 1.2e-06 28.6 0.4 1.9 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.12 AAZ37869.1 - 1.2e-05 24.7 0.0 2.6e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 AAZ37869.1 - 0.00042 20.6 0.1 0.0013 19.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_26 PF13500.6 AAZ37869.1 - 0.00066 19.6 1.9 0.0057 16.5 1.9 2.2 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.20 AAZ37869.1 - 0.00076 19.4 0.2 0.0026 17.7 0.0 2.0 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_33 PF13671.6 AAZ37869.1 - 0.00081 19.6 0.0 0.0019 18.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_31 PF13614.6 AAZ37869.1 - 0.0011 18.9 0.3 0.0046 16.9 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 AAZ37869.1 - 0.0045 16.7 2.0 0.012 15.4 2.0 1.7 1 0 0 1 1 1 1 AAA domain 6PF2K PF01591.18 AAZ37869.1 - 0.0066 15.8 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase cobW PF02492.19 AAZ37869.1 - 0.007 16.0 2.3 0.065 12.8 2.3 2.2 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain DnaB_C PF03796.15 AAZ37869.1 - 0.018 14.4 0.2 0.042 13.2 0.2 1.6 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain KTI12 PF08433.10 AAZ37869.1 - 0.024 14.1 0.0 0.048 13.1 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Thymidylate_kin PF02223.17 AAZ37869.1 - 0.032 13.9 0.5 0.088 12.5 0.5 1.8 1 1 0 1 1 1 0 Thymidylate kinase AAA_24 PF13479.6 AAZ37869.1 - 0.047 13.4 0.1 0.12 12.1 0.1 1.7 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 AAZ37869.1 - 0.05 13.7 1.2 0.27 11.3 0.4 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase HrpJ PF07201.11 AAZ37869.1 - 0.063 13.6 0.3 0.18 12.1 0.3 1.8 1 0 0 1 1 1 0 HrpJ-like domain AAA_18 PF13238.6 AAZ37869.1 - 0.072 13.6 0.3 0.24 11.9 0.0 2.1 3 0 0 3 3 1 0 AAA domain DUF2075 PF09848.9 AAZ37869.1 - 0.096 11.9 0.1 0.2 10.9 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATP_bind_1 PF03029.17 AAZ37869.1 - 0.12 12.2 0.0 0.33 10.7 0.0 1.8 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_5 PF07728.14 AAZ37869.1 - 0.13 12.3 0.4 0.53 10.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 AAZ37869.1 - 0.16 11.9 0.3 0.35 10.8 0.3 1.7 1 1 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 AAZ37869.1 - 0.17 11.8 1.3 2.8 7.8 0.2 2.5 2 0 0 2 2 2 0 NTPase AAA_28 PF13521.6 AAZ37869.1 - 0.19 12.0 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain ArsA_ATPase PF02374.15 AAZ37869.1 - 0.19 10.9 5.6 0.18 10.9 0.2 2.7 3 0 0 3 3 3 0 Anion-transporting ATPase Aminotran_1_2 PF00155.21 AAZ37870.1 - 8.1e-53 179.9 0.0 9.2e-53 179.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 AAZ37870.1 - 9.3e-05 21.5 0.0 0.00013 21.0 0.0 1.1 1 0 0 1 1 1 1 Allinase Cys_Met_Meta_PP PF01053.20 AAZ37870.1 - 0.036 12.6 0.0 0.048 12.2 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DDE_Tnp_4 PF13359.6 AAZ37870.1 - 0.23 11.1 0.0 0.9 9.2 0.0 1.8 2 0 0 2 2 2 0 DDE superfamily endonuclease Bac_luciferase PF00296.20 AAZ37871.1 - 7e-67 226.1 1.7 9.4e-67 225.7 1.7 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Ub-RnfH PF03658.14 AAZ37872.1 - 9.6e-31 106.0 0.0 1.1e-30 105.8 0.0 1.0 1 0 0 1 1 1 1 RnfH family Ubiquitin Orn_Arg_deC_N PF02784.16 AAZ37873.1 - 3.1e-77 259.3 0.0 3.7e-77 259.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 AAZ37873.1 - 1.1e-26 92.9 0.0 1.4e-26 92.5 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ala_racemase_N PF01168.20 AAZ37873.1 - 4.7e-08 33.0 0.0 8.3e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Metallophos PF00149.28 AAZ37875.1 - 3e-11 44.2 0.2 8.9e-11 42.7 0.2 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AAZ37875.1 - 0.00028 21.1 0.0 0.00049 20.3 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain FBPase_2 PF06874.11 AAZ37875.1 - 0.14 10.4 0.0 0.2 9.9 0.0 1.1 1 0 0 1 1 1 0 Firmicute fructose-1,6-bisphosphatase Acetyltransf_1 PF00583.25 AAZ37876.1 - 1.3e-15 57.6 0.0 1.6e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AAZ37876.1 - 2.7e-11 43.5 0.0 3.4e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAZ37876.1 - 4.2e-10 39.9 0.0 7e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AAZ37876.1 - 6.9e-08 32.8 0.1 7.8e-08 32.6 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAZ37876.1 - 1.2e-06 28.4 0.0 2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 AAZ37876.1 - 1.6e-06 27.8 0.0 3.2e-06 26.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AAZ37876.1 - 7.1e-06 26.1 0.0 9e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AAZ37876.1 - 0.00013 22.6 0.0 0.00016 22.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AAZ37876.1 - 0.028 14.5 0.0 0.076 13.2 0.0 1.7 1 1 1 2 2 2 0 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 AAZ37876.1 - 0.076 12.5 0.0 0.093 12.2 0.0 1.4 1 1 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_18 PF18014.1 AAZ37876.1 - 0.085 12.7 0.0 2.3 8.1 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Asp4 PF16996.5 AAZ37877.1 - 0.021 14.6 0.2 0.024 14.4 0.2 1.1 1 0 0 1 1 1 0 Accessory secretory protein Sec Asp4 4HBT PF03061.22 AAZ37878.1 - 3.9e-09 36.8 0.1 9.6e-09 35.5 0.0 1.6 1 1 1 2 2 2 1 Thioesterase superfamily 4HBT_2 PF13279.6 AAZ37878.1 - 1e-08 35.7 0.1 1.2e-08 35.4 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 AAZ37878.1 - 0.0053 16.1 0.3 0.0084 15.4 0.3 1.3 1 1 0 1 1 1 1 Acyl-ACP thioesterase ABC_tran PF00005.27 AAZ37879.1 - 4.4e-34 117.9 0.0 6.3e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAZ37879.1 - 2.2e-13 50.7 0.0 6.9e-06 26.1 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAZ37879.1 - 1.8e-07 30.8 0.1 3.3e-05 23.4 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AAZ37879.1 - 3.3e-06 27.4 0.1 0.00012 22.4 0.1 2.6 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.6 AAZ37879.1 - 6.4e-06 26.7 0.6 3.6e-05 24.2 0.6 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_13 PF13166.6 AAZ37879.1 - 1.8e-05 23.6 0.0 0.0029 16.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 AAZ37879.1 - 7.1e-05 23.4 0.0 0.00011 22.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAZ37879.1 - 0.00014 21.5 0.0 0.00031 20.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_ATPase PF09818.9 AAZ37879.1 - 0.00081 18.3 0.1 0.79 8.4 0.1 2.4 2 1 0 2 2 2 2 Predicted ATPase of the ABC class AAA_15 PF13175.6 AAZ37879.1 - 0.001 18.9 0.0 0.029 14.1 0.0 2.0 1 1 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.6 AAZ37879.1 - 0.0011 19.2 0.4 0.065 13.5 0.0 3.0 2 1 0 3 3 3 1 AAA domain AAA_25 PF13481.6 AAZ37879.1 - 0.0023 17.5 0.2 0.028 14.0 0.0 2.5 2 1 1 3 3 3 1 AAA domain ATPase_2 PF01637.18 AAZ37879.1 - 0.0057 16.6 0.0 0.045 13.7 0.0 2.0 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_33 PF13671.6 AAZ37879.1 - 0.0067 16.6 0.3 0.02 15.1 0.3 2.2 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 AAZ37879.1 - 0.01 16.2 0.0 2.3 8.7 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 AAZ37879.1 - 0.013 15.4 0.1 0.026 14.4 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_24 PF13479.6 AAZ37879.1 - 0.015 15.0 0.0 0.031 14.0 0.0 1.6 2 0 0 2 2 1 0 AAA domain NACHT PF05729.12 AAZ37879.1 - 0.016 15.1 0.0 0.043 13.7 0.0 1.7 1 0 0 1 1 1 0 NACHT domain cobW PF02492.19 AAZ37879.1 - 0.017 14.7 0.0 0.036 13.7 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 AAZ37879.1 - 0.02 15.5 0.1 0.053 14.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AAZ37879.1 - 0.02 14.6 0.3 0.05 13.3 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 AAZ37879.1 - 0.024 14.1 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 AAZ37879.1 - 0.037 13.4 0.1 2.6 7.4 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein AAA_14 PF13173.6 AAZ37879.1 - 0.1 12.7 0.0 0.83 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 AAZ37879.1 - 0.12 11.9 0.0 0.63 9.5 0.0 1.9 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_5 PF07728.14 AAZ37879.1 - 0.13 12.3 0.2 3.2 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 AAZ37879.1 - 0.13 12.6 0.1 0.55 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 AAZ37879.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.23 AAZ37879.1 - 0.14 12.2 0.0 0.39 10.8 0.0 1.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase IstB_IS21 PF01695.17 AAZ37879.1 - 0.17 11.6 0.0 0.71 9.6 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein NB-ARC PF00931.22 AAZ37879.1 - 0.17 11.0 0.1 0.36 10.0 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain G-alpha PF00503.20 AAZ37879.1 - 0.23 10.6 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit DcrB PF08786.11 AAZ37880.1 - 3.3e-05 24.0 0.0 4.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 DcrB DctP PF03480.13 AAZ37881.1 - 1.2e-77 261.1 0.9 1.4e-77 260.9 0.9 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein, family 7 SBP_bac_3 PF00497.20 AAZ37881.1 - 0.0018 17.8 0.0 0.018 14.5 0.0 2.4 2 1 1 3 3 3 1 Bacterial extracellular solute-binding proteins, family 3 Peptidase_S24 PF00717.23 AAZ37882.1 - 3.9e-15 55.5 0.0 1.1e-14 54.1 0.0 1.7 2 0 0 2 2 2 1 Peptidase S24-like HTH_3 PF01381.22 AAZ37882.1 - 1.1e-06 28.6 0.0 1.9e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 AAZ37882.1 - 2.3e-05 24.3 0.0 3.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain YdaS_antitoxin PF15943.5 AAZ37882.1 - 0.0003 20.6 0.2 0.0005 19.9 0.2 1.3 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Phage_CI_repr PF07022.13 AAZ37882.1 - 0.00039 20.5 0.0 0.0016 18.5 0.0 1.9 2 0 0 2 2 2 1 Bacteriophage CI repressor helix-turn-helix domain HTH_31 PF13560.6 AAZ37882.1 - 0.00076 19.8 0.6 0.0013 19.0 0.6 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 AAZ37882.1 - 0.0023 18.3 0.0 0.0043 17.5 0.0 1.4 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_23 PF13384.6 AAZ37882.1 - 0.0048 16.6 0.2 0.011 15.5 0.2 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_37 PF13744.6 AAZ37882.1 - 0.005 16.8 0.1 0.0082 16.1 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain PTH2 PF01981.16 AAZ37882.1 - 0.089 13.1 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Peptidyl-tRNA hydrolase PTH2 HTH_28 PF13518.6 AAZ37882.1 - 0.15 12.2 0.5 0.43 10.7 0.3 1.9 1 1 1 2 2 2 0 Helix-turn-helix domain SP_C-Propep PF08999.10 AAZ37882.1 - 0.33 10.8 6.8 0.61 9.9 6.8 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide DUF2597 PF10772.9 AAZ37883.1 - 3e-62 208.6 0.1 3.4e-62 208.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2597) DUF4381 PF14316.6 AAZ37884.1 - 4.8e-44 150.1 6.1 5.4e-44 150.0 6.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) ABC_tran PF00005.27 AAZ37885.1 - 7.8e-38 130.1 0.0 1.3e-37 129.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter TOBE_3 PF12857.7 AAZ37885.1 - 1.6e-11 43.9 0.3 5.1e-11 42.3 0.1 2.0 1 1 1 2 2 2 1 TOBE-like domain AAA_21 PF13304.6 AAZ37885.1 - 8.1e-10 39.0 0.1 0.001 19.0 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAZ37885.1 - 3.7e-07 29.8 0.0 2.3e-06 27.2 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain TOBE_2 PF08402.10 AAZ37885.1 - 5.5e-05 23.3 0.0 0.00016 21.7 0.0 1.9 1 0 0 1 1 1 1 TOBE domain AAA_23 PF13476.6 AAZ37885.1 - 0.00015 22.3 0.1 0.00029 21.4 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 AAZ37885.1 - 0.00021 21.7 0.0 0.0018 18.7 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AAZ37885.1 - 0.00022 21.7 0.3 0.00059 20.3 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 AAZ37885.1 - 0.0011 18.9 0.0 0.0038 17.2 0.0 1.7 2 0 0 2 2 2 1 Rad17 P-loop domain TOBE PF03459.17 AAZ37885.1 - 0.0023 18.2 0.1 0.0061 16.8 0.1 1.7 1 0 0 1 1 1 1 TOBE domain RsgA_GTPase PF03193.16 AAZ37885.1 - 0.0038 17.1 0.0 0.0072 16.3 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_15 PF13175.6 AAZ37885.1 - 0.0042 16.8 0.0 0.0059 16.4 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 AAZ37885.1 - 0.0062 16.5 0.2 0.025 14.5 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.6 AAZ37885.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 AAZ37885.1 - 0.02 15.2 0.9 0.12 12.6 0.9 2.2 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 AAZ37885.1 - 0.02 14.8 0.0 0.048 13.6 0.0 1.8 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_28 PF13521.6 AAZ37885.1 - 0.02 15.1 0.8 0.061 13.6 0.7 2.1 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 AAZ37885.1 - 0.027 13.8 0.0 5.5 6.3 0.0 2.2 2 0 0 2 2 2 0 KaiC SbcCD_C PF13558.6 AAZ37885.1 - 0.028 14.6 0.1 0.25 11.6 0.1 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 AAZ37885.1 - 0.035 13.7 1.0 0.13 11.8 0.1 2.2 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 AAZ37885.1 - 0.038 13.7 0.4 1.8 8.3 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 AAZ37885.1 - 0.052 13.7 0.1 0.14 12.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 AAZ37885.1 - 0.061 13.4 0.0 0.21 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 AAZ37885.1 - 0.065 13.2 0.1 0.23 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 AAZ37885.1 - 0.067 13.7 0.0 0.16 12.5 0.0 1.8 2 0 0 2 2 1 0 AAA domain TsaE PF02367.17 AAZ37885.1 - 0.079 13.0 0.0 0.22 11.5 0.0 1.7 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 AAZ37885.1 - 0.086 12.6 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 AAZ37885.1 - 0.094 12.2 0.0 1.2 8.5 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein PduV-EutP PF10662.9 AAZ37885.1 - 0.16 11.7 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ABC_ATPase PF09818.9 AAZ37885.1 - 0.16 10.7 0.2 4.5 6.0 0.0 2.7 2 1 0 2 2 2 0 Predicted ATPase of the ABC class DUF4214 PF13946.6 AAZ37886.1 - 6.1e-36 122.3 0.0 5.7e-10 39.1 0.0 4.2 1 1 3 4 4 4 4 Domain of unknown function (DUF4214) HemolysinCabind PF00353.19 AAZ37886.1 - 5.9e-08 32.5 32.8 8.9e-06 25.6 12.3 4.8 2 2 1 3 3 3 2 RTX calcium-binding nonapeptide repeat (4 copies) Menin PF05053.13 AAZ37886.1 - 0.86 7.9 6.2 1.2 7.4 6.2 1.2 1 0 0 1 1 1 0 Menin OpuAC PF04069.12 AAZ37887.1 - 1.1e-63 215.2 0.4 1.3e-63 215.0 0.4 1.0 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system RHS_repeat PF05593.14 AAZ37888.1 - 8.7e-10 38.9 0.4 6.8e-07 29.7 0.0 4.3 2 2 1 4 4 4 3 RHS Repeat Tsi6 PF18660.1 AAZ37889.1 - 7e-30 102.9 0.1 8.3e-30 102.7 0.1 1.1 1 0 0 1 1 1 1 Tsi6 DUF772 PF05598.11 AAZ37890.1 - 1.5e-26 92.2 0.1 3.3e-26 91.1 0.1 1.6 1 0 0 1 1 1 1 Transposase domain (DUF772) HTH_12 PF08461.10 AAZ37890.1 - 0.028 14.4 0.0 0.18 11.8 0.0 2.0 2 0 0 2 2 2 0 Ribonuclease R winged-helix domain Phage_GPD PF05954.11 AAZ37891.1 - 8.6e-22 77.8 0.0 1.2e-21 77.3 0.0 1.2 1 0 0 1 1 1 1 Phage late control gene D protein (GPD) DUF2613 PF11021.8 AAZ37892.1 - 0.011 15.8 0.1 0.022 14.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) PorA PF11271.8 AAZ37892.1 - 0.052 12.8 0.0 0.066 12.5 0.0 1.1 1 0 0 1 1 1 0 Porin PorA DUF4096 PF13340.6 AAZ37893.1 - 5.5e-25 87.4 0.4 1.4e-24 86.1 0.4 1.7 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1 PF01609.21 AAZ37893.1 - 2.8e-14 53.3 0.0 5.1e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AAZ37893.1 - 6.6e-10 39.2 0.2 1.9e-09 37.7 0.2 1.9 1 0 0 1 1 1 1 Transposase DDE domain HTH_Tnp_Tc3_2 PF01498.18 AAZ37893.1 - 0.036 14.3 0.0 0.08 13.2 0.0 1.6 1 0 0 1 1 1 0 Transposase FAD-oxidase_C PF02913.19 AAZ37894.1 - 3.9e-68 229.8 0.1 5e-68 229.4 0.1 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 AAZ37894.1 - 5.4e-39 133.1 0.2 5.4e-39 133.1 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain DAHP_synth_2 PF01474.16 AAZ37895.1 - 4.5e-207 687.8 0.0 5.1e-207 687.6 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family DUF4096 PF13340.6 AAZ37896.1 - 5.8e-25 87.3 0.4 1.5e-24 86.0 0.4 1.8 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1 PF01609.21 AAZ37896.1 - 3.2e-14 53.1 0.0 5.7e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AAZ37896.1 - 7.2e-10 39.1 0.2 2.1e-09 37.6 0.2 1.9 1 0 0 1 1 1 1 Transposase DDE domain HTH_Tnp_Tc3_2 PF01498.18 AAZ37896.1 - 0.061 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Transposase TetR_N PF00440.23 AAZ37898.1 - 9.6e-06 25.3 0.1 2.9e-05 23.8 0.1 1.9 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_31 PF17940.1 AAZ37898.1 - 0.004 17.3 0.6 0.004 17.3 0.6 2.9 3 0 0 3 3 3 1 Tetracyclin repressor-like, C-terminal domain Peptidase_M35 PF02102.15 AAZ37898.1 - 0.053 12.4 0.6 0.076 11.9 0.6 1.2 1 0 0 1 1 1 0 Deuterolysin metalloprotease (M35) family HTH_7 PF02796.15 AAZ37900.1 - 9.4e-07 28.8 0.5 2.5e-06 27.5 0.2 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_38 PF13936.6 AAZ37900.1 - 2.6e-06 27.1 0.2 3.8e-06 26.6 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 AAZ37900.1 - 2.9e-06 26.8 0.1 5.2e-06 26.0 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 AAZ37900.1 - 7.4e-06 25.6 0.0 1.3e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 AAZ37900.1 - 2.5e-05 24.2 0.1 3.7e-05 23.6 0.1 1.4 1 1 0 1 1 1 1 Winged helix-turn helix HTH_30 PF13556.6 AAZ37900.1 - 3.5e-05 23.5 0.1 5.8e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_28 PF13518.6 AAZ37900.1 - 5.4e-05 23.2 0.1 7.2e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_10 PF04967.12 AAZ37900.1 - 0.00013 21.6 0.0 0.00028 20.6 0.0 1.6 1 1 0 1 1 1 1 HTH DNA binding domain HTH_11 PF08279.12 AAZ37900.1 - 0.00019 21.3 0.1 0.00032 20.6 0.1 1.5 1 1 0 1 1 1 1 HTH domain HTH_8 PF02954.19 AAZ37900.1 - 0.0002 21.1 0.0 0.00031 20.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family GerE PF00196.19 AAZ37900.1 - 0.00068 19.1 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_36 PF13730.6 AAZ37900.1 - 0.0011 18.9 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_17 PF12728.7 AAZ37900.1 - 0.0012 18.9 0.6 0.0025 18.0 0.3 1.7 1 1 1 2 2 2 1 Helix-turn-helix domain NUMOD1 PF07453.13 AAZ37900.1 - 0.0022 18.2 0.0 0.0033 17.6 0.0 1.3 1 0 0 1 1 1 1 NUMOD1 domain HTH_22 PF13309.6 AAZ37900.1 - 0.0026 17.8 0.0 0.0045 17.0 0.0 1.4 1 0 0 1 1 1 1 HTH domain HTH_24 PF13412.6 AAZ37900.1 - 0.0038 16.8 0.1 0.008 15.7 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.16 AAZ37900.1 - 0.0045 16.5 0.2 0.007 15.9 0.2 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 Phage_NinH PF06322.11 AAZ37900.1 - 0.0047 16.8 0.0 0.0073 16.2 0.0 1.4 1 0 0 1 1 1 1 Phage NinH protein HTH_IclR PF09339.10 AAZ37900.1 - 0.0053 16.5 0.0 0.016 15.0 0.0 1.8 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_40 PF14493.6 AAZ37900.1 - 0.0086 16.5 0.0 0.0092 16.4 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 AAZ37900.1 - 0.0096 16.0 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix TnsD PF15978.5 AAZ37900.1 - 0.011 14.8 0.0 0.011 14.8 0.0 1.1 1 0 0 1 1 1 0 Tn7-like transposition protein D Sigma70_ECF PF07638.11 AAZ37900.1 - 0.011 15.6 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 ECF sigma factor Terminase_5 PF06056.12 AAZ37900.1 - 0.012 15.5 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) DUF2089 PF09862.9 AAZ37900.1 - 0.028 14.4 0.0 0.03 14.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) HTH_Tnp_1 PF01527.20 AAZ37900.1 - 0.029 14.7 0.0 0.039 14.3 0.0 1.4 1 0 0 1 1 1 0 Transposase GntR PF00392.21 AAZ37900.1 - 0.04 13.6 0.1 0.094 12.4 0.1 1.7 1 1 0 1 1 1 0 Bacterial regulatory proteins, gntR family MarR_2 PF12802.7 AAZ37900.1 - 0.042 13.7 0.1 0.086 12.7 0.1 1.7 1 1 0 1 1 1 0 MarR family HTH_Tnp_ISL3 PF13542.6 AAZ37900.1 - 0.056 12.9 0.6 0.16 11.4 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_Crp_2 PF13545.6 AAZ37900.1 - 0.06 13.3 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain TrmB PF01978.19 AAZ37900.1 - 0.14 12.1 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_Tnp_IS1 PF12759.7 AAZ37900.1 - 0.14 11.8 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 InsA C-terminal domain Transketolase_N PF00456.21 AAZ37901.1 - 2.2e-161 536.4 0.0 3e-161 536.0 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 AAZ37901.1 - 2.2e-48 164.3 0.0 8.4e-48 162.4 0.0 2.0 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 AAZ37901.1 - 8.6e-17 61.2 0.1 1.6e-15 57.1 0.0 2.3 2 0 0 2 2 2 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 AAZ37901.1 - 2e-05 23.9 0.0 0.049 12.8 0.1 2.4 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 AAZ37901.1 - 2.7e-05 24.0 0.1 0.00056 19.7 0.1 2.7 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 AAZ37901.1 - 0.00025 20.1 0.0 0.00048 19.2 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component Form_Nir_trans PF01226.17 AAZ37902.1 - 1.7e-79 266.5 30.7 1.9e-79 266.3 30.7 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter ILVD_EDD PF00920.21 AAZ37903.1 - 6.4e-219 727.8 0.9 7.3e-219 727.7 0.9 1.0 1 0 0 1 1 1 1 Dehydratase family ABM PF03992.16 AAZ37904.1 - 1.2e-08 34.9 0.5 1.6e-08 34.5 0.5 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF4188 PF13826.6 AAZ37904.1 - 0.0056 17.0 0.0 0.0065 16.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) AhpC-TSA PF00578.21 AAZ37905.1 - 2.2e-21 76.1 0.0 2.8e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AAZ37905.1 - 3.9e-15 55.8 0.0 5.4e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin PF00085.20 AAZ37905.1 - 2.8e-10 40.1 0.1 9e-10 38.5 0.1 1.7 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.6 AAZ37905.1 - 1.3e-07 31.9 0.0 2.5e-07 30.9 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like GSHPx PF00255.19 AAZ37905.1 - 0.00068 19.2 0.0 0.001 18.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase Thioredoxin_9 PF14595.6 AAZ37905.1 - 0.0035 17.1 0.0 0.017 14.9 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin SCO1-SenC PF02630.14 AAZ37905.1 - 0.03 14.2 0.0 0.054 13.4 0.0 1.4 1 1 0 1 1 1 0 SCO1/SenC DUF1611 PF07755.11 AAZ37905.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1611_C) P-loop domain LPAM_2 PF13627.6 AAZ37905.1 - 1.2 9.1 4.4 2.1 8.3 4.4 1.5 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site Transposase_mut PF00872.18 AAZ37906.1 - 7e-116 387.2 0.0 8.8e-116 386.9 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ37906.1 - 7.8e-05 23.0 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain ABC_tran PF00005.27 AAZ37907.1 - 4e-29 101.9 0.0 5.4e-29 101.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAZ37907.1 - 1.7e-08 34.7 0.1 0.00056 19.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system oligo_HPY PF08352.12 AAZ37907.1 - 4.6e-05 23.9 0.0 8e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_29 PF13555.6 AAZ37907.1 - 0.0015 18.2 0.1 0.0028 17.4 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AAZ37907.1 - 0.0021 18.0 0.2 0.006 16.5 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase TniB PF05621.11 AAZ37907.1 - 0.0044 16.5 0.4 1.2 8.5 0.2 3.0 2 1 1 3 3 3 1 Bacterial TniB protein AAA_25 PF13481.6 AAZ37907.1 - 0.0094 15.5 0.2 0.26 10.8 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAZ37907.1 - 0.012 16.0 0.4 0.027 14.8 0.4 1.7 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 AAZ37907.1 - 0.015 15.4 0.0 0.019 15.0 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase SbcCD_C PF13558.6 AAZ37907.1 - 0.015 15.5 0.0 0.035 14.4 0.0 1.6 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 AAZ37907.1 - 0.022 15.3 0.0 0.03 14.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AAZ37907.1 - 0.057 13.7 0.0 0.25 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 AAZ37907.1 - 0.13 12.7 0.0 0.3 11.5 0.0 1.6 2 0 0 2 2 1 0 RNA helicase DUF87 PF01935.17 AAZ37907.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_15 PF13175.6 AAZ37907.1 - 0.25 11.0 0.0 4 7.0 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain MOSC PF03473.17 AAZ37908.1 - 4.2e-07 30.0 0.0 1e-06 28.8 0.0 1.7 2 0 0 2 2 2 1 MOSC domain THF_DHG_CYH_C PF02882.19 AAZ37909.1 - 5.7e-68 227.3 0.8 5.7e-68 227.3 0.8 1.5 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 AAZ37909.1 - 6.1e-38 129.7 0.2 8.7e-38 129.2 0.2 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain DUF1884 PF08967.10 AAZ37909.1 - 0.075 13.3 0.2 0.21 11.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1884) Porphobil_deam PF01379.20 AAZ37910.1 - 1.8e-81 272.6 0.0 2.3e-81 272.2 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 AAZ37910.1 - 4.3e-20 71.9 0.1 8.1e-20 71.0 0.1 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain LysR_substrate PF03466.20 AAZ37910.1 - 0.015 14.7 0.6 0.093 12.1 0.0 2.4 3 0 0 3 3 3 0 LysR substrate binding domain GTP_cyclohydroI PF01227.22 AAZ37910.1 - 0.2 11.1 0.0 0.34 10.3 0.0 1.3 1 0 0 1 1 1 0 GTP cyclohydrolase I Acetyltransf_4 PF13420.7 AAZ37911.1 - 6.9e-14 52.3 0.0 8.7e-14 51.9 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAZ37911.1 - 1.6e-13 50.9 0.0 1.8e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAZ37911.1 - 1.8e-11 44.3 0.0 2.6e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAZ37911.1 - 2.7e-10 40.2 0.0 3.6e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AAZ37911.1 - 8.9e-10 39.4 0.1 1e-09 39.2 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 AAZ37911.1 - 0.0002 21.1 0.0 0.0004 20.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAZ37911.1 - 0.0014 18.5 0.0 0.0025 17.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein SHD1 PF03983.12 AAZ37911.1 - 0.066 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 SLA1 homology domain 1, SHD1 GAF_2 PF13185.6 AAZ37912.1 - 6.3e-12 46.0 0.1 8e-12 45.6 0.1 1.1 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 AAZ37912.1 - 8.4e-09 36.2 0.0 1e-08 35.9 0.0 1.1 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 AAZ37912.1 - 0.0084 16.5 0.0 0.01 16.2 0.0 1.3 1 1 0 1 1 1 1 GAF domain Cupin_2 PF07883.11 AAZ37913.1 - 1.7e-19 69.3 0.0 2.4e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 AAZ37913.1 - 2e-06 27.4 0.0 3.8e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) AraC_binding PF02311.19 AAZ37913.1 - 4.8e-06 26.5 0.1 1.1e-05 25.3 0.1 1.6 1 1 0 1 1 1 1 AraC-like ligand binding domain MannoseP_isomer PF01050.18 AAZ37913.1 - 0.0008 19.3 0.0 0.0012 18.7 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase Auxin_BP PF02041.16 AAZ37913.1 - 0.0015 18.3 0.0 0.0026 17.5 0.0 1.5 1 1 0 1 1 1 1 Auxin binding protein EutQ PF06249.12 AAZ37913.1 - 0.0018 18.0 0.0 0.0023 17.7 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_6 PF12852.7 AAZ37913.1 - 0.0051 16.6 0.0 0.0058 16.4 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_1 PF00190.22 AAZ37913.1 - 0.022 14.4 0.1 0.065 12.8 0.0 1.8 2 1 0 2 2 2 0 Cupin Ppnp PF06865.11 AAZ37913.1 - 0.027 14.9 0.0 0.05 14.0 0.0 1.4 1 0 0 1 1 1 0 Pyrimidine/purine nucleoside phosphorylase GGACT PF06094.12 AAZ37913.1 - 0.031 14.9 0.0 3.7 8.2 0.0 2.2 2 0 0 2 2 2 0 Gamma-glutamyl cyclotransferase, AIG2-like DMSP_lyase PF16867.5 AAZ37913.1 - 0.079 12.6 0.1 0.14 11.8 0.0 1.4 1 1 0 1 1 1 0 Dimethlysulfonioproprionate lyase AhpC-TSA PF00578.21 AAZ37914.1 - 1.7e-33 115.2 0.1 2.1e-33 114.9 0.1 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AAZ37914.1 - 4.4e-13 49.2 0.0 5.4e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 AAZ37914.1 - 1.1e-06 28.3 0.1 2.2e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 AAZ37914.1 - 7.4e-06 25.9 0.0 2.5e-05 24.2 0.1 1.7 2 0 0 2 2 2 1 SCO1/SenC DUF3986 PF13143.6 AAZ37914.1 - 0.022 15.8 0.2 0.034 15.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3986) CobN-Mg_chel PF02514.16 AAZ37915.1 - 0 1336.4 0.0 0 1336.2 0.0 1.0 1 0 0 1 1 1 1 CobN/Magnesium Chelatase RsgA_GTPase PF03193.16 AAZ37916.1 - 8.3e-56 188.5 0.0 1.1e-55 188.1 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 AAZ37916.1 - 3.1e-06 27.3 0.0 7.9e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AAZ37916.1 - 4.2e-05 23.1 0.0 0.23 11.0 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 AAZ37916.1 - 0.00054 19.6 0.0 0.02 14.5 0.0 2.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 AAZ37916.1 - 0.0015 18.9 1.5 0.014 15.8 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 AAZ37916.1 - 0.0041 16.8 0.1 0.0098 15.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 AAZ37916.1 - 0.0078 16.7 0.1 0.016 15.7 0.0 1.5 2 0 0 2 2 1 1 ABC transporter Ras PF00071.22 AAZ37916.1 - 0.026 14.1 0.0 1.4 8.5 0.0 2.2 2 0 0 2 2 2 0 Ras family AIG1 PF04548.16 AAZ37916.1 - 0.045 13.1 0.1 0.09 12.1 0.1 1.5 1 0 0 1 1 1 0 AIG1 family Septin PF00735.18 AAZ37916.1 - 0.049 12.9 0.1 0.074 12.3 0.1 1.2 1 0 0 1 1 1 0 Septin Roc PF08477.13 AAZ37916.1 - 0.072 13.3 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 AAZ37916.1 - 0.13 11.7 0.1 0.23 10.9 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region cobW PF02492.19 AAZ37916.1 - 0.16 11.6 0.1 11 5.6 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 AAZ37916.1 - 0.2 11.7 1.3 1.1 9.3 0.9 2.1 1 1 0 2 2 2 0 Dynamin family DUF815 PF05673.13 AAZ37916.1 - 0.23 10.6 0.0 0.46 9.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) CT_A_B PF02626.15 AAZ37917.1 - 1.2e-87 294.0 0.1 1.3e-87 293.8 0.1 1.0 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B SBP_bac_1 PF01547.25 AAZ37918.1 - 1.9e-46 159.5 6.9 1.9e-46 159.5 6.9 1.5 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 AAZ37918.1 - 2e-28 100.0 10.1 2.6e-28 99.6 10.1 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein ATE_C PF04377.15 AAZ37919.1 - 1.6e-40 138.8 0.3 2.4e-40 138.3 0.3 1.2 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 AAZ37919.1 - 1.1e-19 70.6 0.0 2.3e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.7 AAZ37919.1 - 4.7e-07 30.1 0.5 6.1e-07 29.7 0.5 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain OprD PF03573.13 AAZ37920.1 - 1.3e-134 449.1 14.6 1.5e-134 449.0 14.6 1.0 1 0 0 1 1 1 1 outer membrane porin, OprD family DUF2897 PF11446.8 AAZ37922.1 - 3.3e-24 84.5 0.0 3.6e-24 84.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2897) UPF0370 PF13980.6 AAZ37922.1 - 0.0048 16.9 0.0 0.0056 16.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0370) LapA_dom PF06305.11 AAZ37922.1 - 0.022 14.6 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DivIC PF04977.15 AAZ37922.1 - 0.087 12.6 0.0 0.099 12.4 0.0 1.0 1 0 0 1 1 1 0 Septum formation initiator DUF2621 PF11084.8 AAZ37922.1 - 0.1 12.6 0.0 0.1 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) HTH_53 PF18606.1 AAZ37922.1 - 0.12 12.0 0.1 0.14 11.8 0.1 1.1 1 0 0 1 1 1 0 Zap helix turn helix N-terminal domain Transposase_20 PF02371.16 AAZ37924.1 - 9.8e-25 86.7 0.8 2.2e-24 85.6 0.4 1.9 1 1 0 1 1 1 1 Transposase IS116/IS110/IS902 family DEDD_Tnp_IS110 PF01548.17 AAZ37924.1 - 1e-18 67.7 0.0 2.1e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 Transposase TetR_N PF00440.23 AAZ37924.1 - 0.19 11.5 3.0 5.7 6.8 0.0 3.5 4 0 0 4 4 4 0 Bacterial regulatory proteins, tetR family MCPsignal PF00015.21 AAZ37925.1 - 8.6e-45 152.6 23.8 8.6e-45 152.6 23.8 5.0 3 2 1 4 4 4 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HBM PF16591.5 AAZ37925.1 - 9.6e-18 64.5 15.0 9.6e-18 64.5 15.0 3.5 2 1 2 4 4 4 1 Helical bimodular sensor domain HAMP PF00672.25 AAZ37925.1 - 6.6e-11 42.4 22.8 1.6e-09 38.0 0.4 6.6 7 3 0 7 7 7 2 HAMP domain UPF0444 PF15475.6 AAZ37925.1 - 0.002 18.4 0.4 0.0083 16.4 0.4 2.1 1 0 0 1 1 1 1 Transmembrane protein C12orf23, UPF0444 Syntaxin_2 PF14523.6 AAZ37925.1 - 0.0042 17.4 19.4 0.55 10.6 1.0 5.8 4 1 2 6 6 6 2 Syntaxin-like protein Med28 PF11594.8 AAZ37925.1 - 0.0061 16.6 5.4 1.4 9.0 0.1 3.4 4 0 0 4 4 4 2 Mediator complex subunit 28 BLOC1_2 PF10046.9 AAZ37925.1 - 0.2 12.0 24.0 2.1 8.7 0.0 6.0 5 2 0 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.11 AAZ37925.1 - 0.34 11.2 38.9 9.8 6.5 8.7 7.1 4 3 1 5 5 5 0 Bacterial protein of unknown function (DUF948) SOGA PF11365.8 AAZ37925.1 - 5.2 8.3 8.9 16 6.7 0.7 3.7 3 0 0 3 3 3 0 Protein SOGA Sua5_yciO_yrdC PF01300.18 AAZ37926.1 - 3.5e-45 153.7 0.0 4.1e-45 153.5 0.0 1.0 1 0 0 1 1 1 1 Telomere recombination HDOD PF08668.12 AAZ37927.1 - 5.8e-37 127.1 0.6 8e-37 126.6 0.6 1.2 1 0 0 1 1 1 1 HDOD domain Response_reg PF00072.24 AAZ37927.1 - 6.3e-16 58.5 0.0 1.8e-15 57.1 0.0 1.8 2 0 0 2 2 2 1 Response regulator receiver domain TetR_C_7 PF14246.6 AAZ37928.1 - 3.7e-30 104.4 0.6 1.1e-29 102.9 0.0 2.0 3 0 0 3 3 3 1 AefR-like transcriptional repressor, C-terminal domain TetR_N PF00440.23 AAZ37928.1 - 2.8e-19 68.6 0.1 1.3e-18 66.5 0.1 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 AAZ37928.1 - 3.9e-05 23.9 0.2 9.9e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_24 PF17932.1 AAZ37928.1 - 0.0052 17.0 0.1 0.012 15.8 0.1 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_6 PF13977.6 AAZ37928.1 - 0.029 14.6 0.2 0.069 13.4 0.2 1.8 1 0 0 1 1 1 0 BetI-type transcriptional repressor, C-terminal HTH_22 PF13309.6 AAZ37928.1 - 0.069 13.2 0.1 0.28 11.3 0.1 2.0 1 1 0 1 1 1 0 HTH domain HTH_36 PF13730.6 AAZ37928.1 - 0.099 12.6 0.0 0.38 10.7 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain ABC_tran PF00005.27 AAZ37929.1 - 2.8e-30 105.6 0.0 3.8e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAZ37929.1 - 1.5e-14 54.5 1.2 3.7e-06 27.0 0.2 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAZ37929.1 - 3e-10 39.9 0.0 6.1e-08 32.4 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 AAZ37929.1 - 1.5e-08 34.8 0.0 7.8e-05 22.5 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 AAZ37929.1 - 5.8e-07 29.2 0.0 1.3e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AAZ37929.1 - 1.6e-06 28.7 0.0 2.5e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAZ37929.1 - 3.3e-05 24.3 0.2 5.9e-05 23.5 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 AAZ37929.1 - 0.00043 20.1 0.0 0.00079 19.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AAZ37929.1 - 0.001 19.4 0.2 0.0035 17.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain MukB PF04310.12 AAZ37929.1 - 0.0017 18.2 0.1 0.013 15.3 0.0 2.0 2 0 0 2 2 2 1 MukB N-terminal Rad17 PF03215.15 AAZ37929.1 - 0.002 18.1 0.0 0.0041 17.1 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 AAZ37929.1 - 0.002 18.5 0.0 0.0039 17.6 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_27 PF13514.6 AAZ37929.1 - 0.006 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 AAZ37929.1 - 0.0066 16.5 0.1 0.046 13.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 AAZ37929.1 - 0.0089 16.1 0.0 0.039 14.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 AAZ37929.1 - 0.0093 15.4 0.0 0.023 14.1 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 AAZ37929.1 - 0.017 15.0 0.0 0.042 13.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 AAZ37929.1 - 0.018 15.4 0.0 0.039 14.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 AAZ37929.1 - 0.022 14.7 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 AAZ37929.1 - 0.031 14.4 0.0 0.095 12.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AAZ37929.1 - 0.031 14.0 0.0 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 AAZ37929.1 - 0.034 12.9 0.1 1.1 8.0 0.0 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_28 PF13521.6 AAZ37929.1 - 0.034 14.4 0.0 0.07 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 AAZ37929.1 - 0.054 13.8 0.1 0.14 12.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain DUF2813 PF11398.8 AAZ37929.1 - 0.055 12.7 0.0 0.081 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) ATPase_2 PF01637.18 AAZ37929.1 - 0.059 13.3 0.0 0.073 13.0 0.0 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea TniB PF05621.11 AAZ37929.1 - 0.11 11.9 0.1 1.4 8.3 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein AAA_25 PF13481.6 AAZ37929.1 - 0.12 11.9 0.6 0.24 10.9 0.0 1.7 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 AAZ37929.1 - 0.16 11.2 0.0 0.39 10.0 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin G-alpha PF00503.20 AAZ37929.1 - 0.23 10.6 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit ExbD PF02472.16 AAZ37930.1 - 2.2e-27 95.8 4.3 2.5e-27 95.6 4.3 1.0 1 0 0 1 1 1 1 Biopolymer transport protein ExbD/TolR TPR_19 PF14559.6 AAZ37930.1 - 0.018 15.6 0.1 0.029 14.9 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF2149 PF09919.9 AAZ37930.1 - 0.031 14.5 1.5 0.039 14.2 1.2 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) DUF4320 PF14208.6 AAZ37930.1 - 0.063 13.4 0.2 0.078 13.1 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4320) DUF1654 PF07867.11 AAZ37931.1 - 7.2e-23 80.1 0.5 9.4e-23 79.7 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1654) Gln-synt_C PF00120.24 AAZ37932.1 - 8.8e-108 360.4 0.0 1e-107 360.1 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 AAZ37932.1 - 0.00076 19.3 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase N-terminal domain Gln-synt_N PF03951.19 AAZ37932.1 - 0.065 13.0 0.0 0.92 9.3 0.0 2.5 1 1 0 1 1 1 0 Glutamine synthetase, beta-Grasp domain G2F PF07474.12 AAZ37932.1 - 0.21 11.3 0.0 0.38 10.5 0.0 1.3 1 0 0 1 1 1 0 G2F domain MMR_HSR1 PF01926.23 AAZ37933.1 - 8.1e-24 83.9 0.2 1.4e-23 83.2 0.2 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase KH_2 PF07650.17 AAZ37933.1 - 2.3e-20 72.2 0.3 4.6e-20 71.2 0.3 1.5 1 0 0 1 1 1 1 KH domain FeoB_N PF02421.18 AAZ37933.1 - 1.1e-14 54.3 0.1 1.7e-14 53.6 0.1 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.16 AAZ37933.1 - 3.6e-10 39.5 0.0 5.8e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 AAZ37933.1 - 1.3e-09 38.4 0.6 2.6e-05 24.3 0.1 2.3 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 AAZ37933.1 - 1.5e-09 37.7 0.4 5.9e-07 29.2 0.4 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 AAZ37933.1 - 5.9e-08 32.8 0.6 0.00025 21.0 0.2 2.4 2 0 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 AAZ37933.1 - 1.1e-05 25.3 0.0 6.4e-05 22.7 0.0 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 AAZ37933.1 - 4.1e-05 23.3 0.7 0.011 15.4 0.1 2.4 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain Gtr1_RagA PF04670.12 AAZ37933.1 - 0.00041 19.8 0.0 0.00066 19.1 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1_Xtn PF16897.5 AAZ37933.1 - 0.0013 18.7 0.0 0.0023 17.9 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain SRPRB PF09439.10 AAZ37933.1 - 0.0026 17.2 0.0 0.0047 16.4 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 AAZ37933.1 - 0.0051 17.2 0.3 0.32 11.4 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain Roc PF08477.13 AAZ37933.1 - 0.0059 16.8 0.2 0.028 14.6 0.2 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 AAZ37933.1 - 0.013 16.0 0.0 0.036 14.6 0.0 1.8 2 0 0 2 2 2 0 ABC transporter Ploopntkinase3 PF18751.1 AAZ37933.1 - 0.036 14.0 0.1 0.073 13.0 0.0 1.5 1 1 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_22 PF13401.6 AAZ37933.1 - 0.053 13.8 0.5 0.31 11.3 0.1 2.2 1 1 0 2 2 2 0 AAA domain DXP_synthase_N PF13292.6 AAZ37934.1 - 0.015 14.5 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase DDE_Tnp_1 PF01609.21 AAZ37935.1 - 5.3e-15 55.7 0.0 8e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AAZ37935.1 - 3.1e-10 40.3 0.2 5.3e-10 39.5 0.2 1.5 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 AAZ37935.1 - 0.1 12.6 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Transposase DDE domain FKBP_C PF00254.28 AAZ37936.1 - 1.6e-19 70.0 0.0 3.1e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N PF01346.18 AAZ37936.1 - 3.2e-14 53.6 0.0 5.3e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase DUF4827 PF16109.5 AAZ37936.1 - 0.071 13.1 0.0 0.37 10.8 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4827) Rieske PF00355.26 AAZ37937.1 - 7.1e-08 32.3 0.1 1e-07 31.8 0.1 1.3 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 AAZ37937.1 - 0.0013 18.6 0.0 0.0015 18.5 0.0 1.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain 4PPT_N PF17837.1 AAZ37938.1 - 1.7e-24 85.7 1.0 3.1e-24 84.9 1.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase N-terminal domain ACPS PF01648.20 AAZ37938.1 - 2e-11 44.0 0.1 3.4e-10 40.1 0.0 2.1 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily QH-AmDH_gamma PF08992.11 AAZ37938.1 - 0.08 13.0 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, gamma subunit BPD_transp_1 PF00528.22 AAZ37939.1 - 9.8e-24 84.1 12.8 9.8e-24 84.1 12.8 1.8 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component TerC PF03741.16 AAZ37940.1 - 1.1e-40 139.3 8.9 1.1e-40 139.3 8.9 2.7 3 0 0 3 3 3 2 Integral membrane protein TerC family TatC PF00902.18 AAZ37941.1 - 1.2e-64 218.0 26.5 1.4e-64 217.8 26.5 1.1 1 0 0 1 1 1 1 Sec-independent protein translocase protein (TatC) DUF1180 PF06679.12 AAZ37941.1 - 0.15 12.5 0.0 0.36 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF5389 PF17364.2 AAZ37941.1 - 0.46 10.5 6.0 0.2 11.7 2.6 2.1 2 1 1 3 3 3 0 Family of unknown function (DUF5389) DUF2721 PF11026.8 AAZ37942.1 - 0.0093 15.9 3.2 0.0099 15.8 3.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2721) PapD_N PF00345.20 AAZ37943.1 - 1.3e-36 125.2 0.0 2e-36 124.6 0.0 1.3 1 0 0 1 1 1 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain PapD_C PF02753.17 AAZ37943.1 - 2.4e-10 40.6 0.0 5.7e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Pili assembly chaperone PapD, C-terminal domain Transposase_mut PF00872.18 AAZ37944.1 - 2.6e-51 174.6 0.0 3.3e-51 174.3 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ37944.1 - 0.0032 17.9 0.0 0.0085 16.5 0.0 1.7 2 0 0 2 2 2 1 MULE transposase domain DUF4844 PF16133.5 AAZ37944.1 - 0.072 13.7 0.0 0.18 12.4 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4844) DUF4096 PF13340.6 AAZ37945.1 - 5.9e-25 87.3 0.4 1.5e-24 86.0 0.4 1.7 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1 PF01609.21 AAZ37945.1 - 3.2e-14 53.1 0.0 5.7e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AAZ37945.1 - 6.8e-10 39.2 0.2 2.1e-09 37.6 0.2 1.9 1 0 0 1 1 1 1 Transposase DDE domain IstB_IS21 PF01695.17 AAZ37946.1 - 1.8e-33 115.7 0.0 2.1e-33 115.5 0.0 1.0 1 0 0 1 1 1 1 IstB-like ATP binding protein HTH_Tnp_1 PF01527.20 AAZ37948.1 - 1.3e-11 44.6 0.2 1.6e-11 44.4 0.2 1.2 1 1 0 1 1 1 1 Transposase HTH_29 PF13551.6 AAZ37948.1 - 0.0031 17.5 0.4 0.0057 16.6 0.4 1.6 1 1 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.6 AAZ37948.1 - 0.0041 16.9 0.2 0.0077 16.0 0.1 1.5 1 1 0 1 1 1 1 Homeodomain-like domain VirB8 PF04335.13 AAZ37949.1 - 6.1e-11 42.6 0.3 7e-11 42.4 0.3 1.0 1 0 0 1 1 1 1 VirB8 protein Flagellar_rod PF05149.12 AAZ37949.1 - 0.047 13.2 0.0 0.052 13.0 0.0 1.1 1 0 0 1 1 1 0 Paraflagellar rod protein Big_1 PF02369.16 AAZ37949.1 - 0.14 12.2 0.7 0.84 9.7 0.7 2.0 1 1 1 2 2 2 0 Bacterial Ig-like domain (group 1) CDT1_C PF16679.5 AAZ37950.1 - 0.12 12.8 0.0 0.22 12.0 0.0 1.3 1 0 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain YopE PF03545.13 AAZ37951.1 - 0.091 12.9 0.0 0.1 12.8 0.0 1.1 1 0 0 1 1 1 0 Yersinia virulence determinant (YopE) DDE_Tnp_Tn3 PF01526.17 AAZ37955.1 - 0.00072 18.4 0.0 0.00077 18.3 0.0 1.0 1 0 0 1 1 1 1 Tn3 transposase DDE domain KORA PF16509.5 AAZ37957.1 - 2e-10 40.8 0.5 4.1e-10 39.8 0.5 1.6 1 1 0 1 1 1 1 TrfB plasmid transcriptional repressor HTH_23 PF13384.6 AAZ37957.1 - 0.026 14.3 0.3 0.049 13.4 0.3 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_29 PF13551.6 AAZ37957.1 - 0.076 13.0 1.2 0.17 11.9 1.2 1.6 1 0 0 1 1 1 0 Winged helix-turn helix Sigma70_r4_2 PF08281.12 AAZ37957.1 - 0.1 12.3 2.0 0.17 11.6 0.9 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 DUF134 PF02001.16 AAZ37957.1 - 0.12 12.9 0.5 0.19 12.3 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF134 HTH_18 PF12833.7 AAZ37957.1 - 0.18 12.1 2.1 0.13 12.5 0.5 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain Transposase_20 PF02371.16 AAZ37958.1 - 9.8e-25 86.7 0.8 2.2e-24 85.6 0.4 1.9 1 1 0 1 1 1 1 Transposase IS116/IS110/IS902 family DEDD_Tnp_IS110 PF01548.17 AAZ37958.1 - 1e-18 67.7 0.0 2.1e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 Transposase TetR_N PF00440.23 AAZ37958.1 - 0.19 11.5 3.0 5.7 6.8 0.0 3.5 4 0 0 4 4 4 0 Bacterial regulatory proteins, tetR family DUF2513 PF10711.9 AAZ37959.1 - 2.6e-19 69.4 0.0 2.8e-19 69.3 0.0 1.0 1 0 0 1 1 1 1 Hypothetical protein (DUF2513) Transposase_mut PF00872.18 AAZ37960.1 - 1.8e-61 208.1 0.0 2.2e-61 207.8 0.0 1.1 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ37960.1 - 0.00025 21.4 0.0 0.00061 20.2 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain DUF4844 PF16133.5 AAZ37960.1 - 0.14 12.7 0.0 0.3 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) DUF2721 PF11026.8 AAZ37961.1 - 0.0093 15.9 3.2 0.0099 15.8 3.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2721) LysR_substrate PF03466.20 AAZ37963.1 - 8.6e-25 87.3 0.0 1.1e-24 87.0 0.0 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAZ37963.1 - 4.1e-17 61.9 0.6 8.5e-17 60.9 0.6 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 AAZ37963.1 - 0.0066 16.3 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 MarR family HTH_28 PF13518.6 AAZ37963.1 - 0.067 13.3 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 AAZ37963.1 - 0.087 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix TauD PF02668.16 AAZ37964.1 - 3.1e-26 92.8 0.0 3.7e-26 92.5 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 AAZ37964.1 - 0.0011 18.2 0.0 0.015 14.4 0.0 2.0 2 0 0 2 2 2 1 CsiD EAL PF00563.20 AAZ37965.1 - 5.6e-65 219.2 0.0 8.3e-65 218.6 0.0 1.3 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AAZ37965.1 - 1.6e-36 125.4 0.0 4e-36 124.2 0.0 1.6 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Holin_BlyA PF05102.12 AAZ37965.1 - 0.047 13.6 0.1 0.15 12.0 0.1 1.9 1 0 0 1 1 1 0 holin, BlyA family AvrB_AvrC PF05394.11 AAZ37967.1 - 6.7e-153 508.6 0.2 7.7e-153 508.4 0.2 1.0 1 0 0 1 1 1 1 Avirulence protein PemK_toxin PF02452.17 AAZ37969.1 - 7.5e-18 65.0 0.0 8.2e-18 64.8 0.0 1.0 1 0 0 1 1 1 1 PemK-like, MazF-like toxin of type II toxin-antitoxin system Tox-ODYAM1 PF15642.6 AAZ37969.1 - 0.005 15.9 0.0 0.0051 15.8 0.0 1.1 1 0 0 1 1 1 1 Toxin in Odyssella and Amoebophilus Sulfotransfer_3 PF13469.6 AAZ37971.1 - 2.9e-10 40.9 0.4 8.1e-05 23.1 0.1 2.2 1 1 0 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 AAZ37971.1 - 1.5e-05 24.6 0.0 9.8e-05 22.0 0.0 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulphotransf PF09037.10 AAZ37971.1 - 3.9e-05 23.3 0.3 0.0024 17.4 0.0 2.5 2 1 0 2 2 2 2 Stf0 sulphotransferase SPA PF08616.10 AAZ37971.1 - 0.091 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis AvrPtoB-E3_ubiq PF09046.10 AAZ37972.1 - 1.3e-60 203.2 0.1 2.3e-60 202.4 0.1 1.4 1 0 0 1 1 1 1 AvrPtoB E3 ubiquitin ligase AvrPtoB_bdg PF16847.5 AAZ37972.1 - 1.5e-21 76.7 1.9 3.6e-20 72.2 0.2 2.6 2 0 0 2 2 2 1 Avirulence AvrPtoB, BAK1-binding domain ParE_toxin PF05016.15 AAZ37973.1 - 8e-18 64.8 0.2 8.8e-18 64.7 0.2 1.0 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE DEDD_Tnp_IS110 PF01548.17 AAZ37974.1 - 1.5e-18 67.2 0.0 2.4e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Transposase IU_nuc_hydro PF01156.19 AAZ37975.1 - 1.9e-09 37.5 0.0 2.6e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase MCPsignal PF00015.21 AAZ37976.1 - 1.7e-39 135.4 28.9 1.7e-39 135.4 28.9 3.3 2 1 1 3 3 3 1 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AAZ37976.1 - 7.8e-07 29.4 14.2 2.2e-06 28.0 0.2 6.2 7 0 0 7 7 7 1 HAMP domain DUF1664 PF07889.12 AAZ37976.1 - 0.012 15.6 0.3 0.012 15.6 0.3 4.5 4 1 1 5 5 5 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 AAZ37976.1 - 0.16 12.3 21.9 6.3 7.1 0.6 5.9 4 2 0 4 4 4 0 Bacterial protein of unknown function (DUF948) AIP3 PF03915.13 AAZ37976.1 - 1.2 8.2 13.9 4.1 6.4 4.6 2.7 2 1 1 3 3 3 0 Actin interacting protein 3 FliD_N PF02465.18 AAZ37976.1 - 2.4 8.9 16.9 0.24 12.1 1.8 3.5 4 0 0 4 4 4 0 Flagellar hook-associated protein 2 N-terminus TMPIT PF07851.13 AAZ37976.1 - 7 5.8 6.3 7.9 5.6 1.2 2.5 2 0 0 2 2 2 0 TMPIT-like protein Glyco_hydro_28 PF00295.17 AAZ37978.1 - 8.1e-50 169.7 1.9 1.1e-49 169.2 1.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Y2_Tnp PF04986.13 AAZ37979.1 - 6.6e-47 159.9 1.4 1e-46 159.3 1.4 1.3 1 0 0 1 1 1 1 Putative transposase Zn_Tnp_IS91 PF14319.6 AAZ37979.1 - 2.5e-22 78.7 7.6 5e-22 77.7 7.6 1.5 1 0 0 1 1 1 1 Transposase zinc-binding domain zf-B_box PF00643.24 AAZ37979.1 - 0.15 12.2 12.7 0.39 10.9 12.7 1.7 1 0 0 1 1 1 0 B-box zinc finger KORA PF16509.5 AAZ37980.1 - 2.4e-10 40.5 0.2 5.6e-10 39.4 0.1 1.7 1 1 0 1 1 1 1 TrfB plasmid transcriptional repressor HTH_23 PF13384.6 AAZ37980.1 - 0.012 15.4 0.5 0.054 13.3 0.2 2.1 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_1 PF01527.20 AAZ37980.1 - 0.027 14.8 0.2 0.3 11.4 0.3 2.1 2 0 0 2 2 2 0 Transposase Sigma70_r4_2 PF08281.12 AAZ37980.1 - 0.031 14.0 0.5 0.93 9.2 0.3 2.3 2 0 0 2 2 2 0 Sigma-70, region 4 MarR_2 PF12802.7 AAZ37980.1 - 0.036 13.9 0.9 0.073 13.0 0.9 1.5 1 0 0 1 1 1 0 MarR family AlkA_N PF06029.11 AAZ37980.1 - 0.04 14.2 0.2 0.056 13.7 0.2 1.3 1 1 0 1 1 1 0 AlkA N-terminal domain DUF4730 PF15873.5 AAZ37980.1 - 0.44 10.9 3.4 2 8.8 0.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4730) CsrA PF02599.16 AAZ37981.1 - 1.3e-15 57.0 0.9 1.7e-15 56.7 0.9 1.2 1 0 0 1 1 1 1 Global regulator protein family HTH_Tnp_1 PF01527.20 AAZ37982.1 - 3.4e-16 59.3 0.9 4e-16 59.1 0.9 1.1 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 AAZ37982.1 - 8.3e-07 28.6 0.4 1.5e-06 27.8 0.0 1.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 AAZ37982.1 - 1.3e-06 27.7 0.0 2.1e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.6 AAZ37982.1 - 7.3e-06 26.0 0.0 1.3e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 AAZ37982.1 - 4.7e-05 23.8 0.2 0.00021 21.7 0.0 1.8 1 1 0 2 2 2 1 leucine-zipper of insertion element IS481 HTH_17 PF12728.7 AAZ37982.1 - 0.00082 19.5 0.0 0.0017 18.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Terminase_5 PF06056.12 AAZ37982.1 - 0.0012 18.7 0.1 0.0019 18.0 0.1 1.4 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) HTH_29 PF13551.6 AAZ37982.1 - 0.0058 16.6 0.0 0.0072 16.3 0.0 1.4 1 1 0 1 1 1 1 Winged helix-turn helix Phage_CI_repr PF07022.13 AAZ37982.1 - 0.011 15.9 0.0 0.016 15.3 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain Ada3 PF10198.9 AAZ37982.1 - 0.015 15.5 2.1 0.017 15.2 2.0 1.3 1 1 0 1 1 1 0 Histone acetyltransferases subunit 3 MerR PF00376.23 AAZ37982.1 - 0.016 14.9 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 MerR family regulatory protein HTH_22 PF13309.6 AAZ37982.1 - 0.03 14.4 0.4 0.066 13.3 0.0 1.9 2 1 0 2 2 2 0 HTH domain MerR_1 PF13411.6 AAZ37982.1 - 0.033 14.3 0.1 0.067 13.3 0.1 1.7 2 1 0 2 2 1 0 MerR HTH family regulatory protein TEX13 PF15186.6 AAZ37982.1 - 0.037 13.7 0.4 0.041 13.6 0.4 1.2 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family HTH_3 PF01381.22 AAZ37982.1 - 0.038 14.1 0.1 0.1 12.7 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix CENP-H PF05837.12 AAZ37982.1 - 0.048 14.1 0.5 0.053 13.9 0.5 1.0 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Gon7 PF08738.10 AAZ37982.1 - 0.056 13.5 0.1 0.063 13.4 0.1 1.2 1 0 0 1 1 1 0 Gon7 family TetR_N PF00440.23 AAZ37982.1 - 0.14 12.0 0.4 0.32 10.8 0.0 1.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family zf-CCCH_6 PF18585.1 AAZ37982.1 - 0.15 11.9 0.1 0.32 10.9 0.1 1.5 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 DUF4140 PF13600.6 AAZ37982.1 - 0.4 11.2 3.4 0.5 10.8 3.4 1.3 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) PIN PF01850.21 AAZ37983.1 - 1.6e-07 31.8 0.0 5.8e-07 30.0 0.0 1.8 1 1 0 1 1 1 1 PIN domain Transposase_20 PF02371.16 AAZ37984.1 - 9.8e-25 86.7 0.8 2.2e-24 85.6 0.4 1.9 1 1 0 1 1 1 1 Transposase IS116/IS110/IS902 family DEDD_Tnp_IS110 PF01548.17 AAZ37984.1 - 1e-18 67.7 0.0 2.1e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 Transposase TetR_N PF00440.23 AAZ37984.1 - 0.19 11.5 3.0 5.7 6.8 0.0 3.5 4 0 0 4 4 4 0 Bacterial regulatory proteins, tetR family Transposase_20 PF02371.16 AAZ37985.1 - 9.5e-25 86.7 0.8 2.2e-24 85.6 0.3 1.9 1 1 0 1 1 1 1 Transposase IS116/IS110/IS902 family DEDD_Tnp_IS110 PF01548.17 AAZ37985.1 - 1e-18 67.7 0.0 2.1e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 Transposase TetR_N PF00440.23 AAZ37985.1 - 0.2 11.5 3.0 5.7 6.8 0.0 3.5 4 0 0 4 4 4 0 Bacterial regulatory proteins, tetR family HNH_5 PF14279.6 AAZ37986.1 - 2.6e-14 52.8 0.3 4.9e-14 51.9 0.3 1.5 1 0 0 1 1 1 1 HNH endonuclease Endonuclease_7 PF02945.15 AAZ37986.1 - 0.028 14.4 0.0 0.061 13.3 0.0 1.6 1 0 0 1 1 1 0 Recombination endonuclease VII AvrD PF05655.11 AAZ37987.1 - 3.9e-66 223.6 0.0 6e-66 223.0 0.0 1.2 1 0 0 1 1 1 1 Pseudomonas avirulence D protein (AvrD) Resolvase PF00239.21 AAZ37988.1 - 7.9e-42 142.8 0.0 1.3e-41 142.1 0.0 1.3 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_7 PF02796.15 AAZ37988.1 - 1.1e-08 35.0 0.0 3.4e-08 33.4 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_29 PF13551.6 AAZ37988.1 - 7.9e-05 22.6 0.1 0.00022 21.2 0.1 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_38 PF13936.6 AAZ37988.1 - 0.0017 18.0 0.0 0.0041 16.9 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_17 PF12728.7 AAZ37988.1 - 0.0018 18.4 0.0 0.0048 17.1 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_6 PF01418.17 AAZ37988.1 - 0.002 18.1 0.0 0.0037 17.2 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain, rpiR family HTH_23 PF13384.6 AAZ37988.1 - 0.0021 17.8 0.0 0.0065 16.2 0.0 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_22 PF13309.6 AAZ37988.1 - 0.0028 17.7 0.1 0.0062 16.6 0.1 1.6 1 0 0 1 1 1 1 HTH domain HTH_11 PF08279.12 AAZ37988.1 - 0.0074 16.2 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 HTH domain UPF0122 PF04297.14 AAZ37988.1 - 0.016 15.4 0.0 0.029 14.6 0.0 1.4 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like HTH_Tnp_4 PF13613.6 AAZ37988.1 - 0.022 14.5 0.0 0.076 12.8 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_32 PF13565.6 AAZ37988.1 - 0.036 14.7 0.6 0.12 13.0 0.1 2.0 2 1 0 2 2 2 0 Homeodomain-like domain HTH_IclR PF09339.10 AAZ37988.1 - 0.038 13.8 0.2 0.16 11.8 0.0 2.2 2 0 0 2 2 1 0 IclR helix-turn-helix domain HTH_psq PF05225.16 AAZ37988.1 - 0.055 13.2 0.7 8.2 6.3 0.0 2.8 3 0 0 3 3 3 0 helix-turn-helix, Psq domain MarR PF01047.22 AAZ37988.1 - 0.099 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_5 PF01022.20 AAZ37988.1 - 0.13 12.1 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family DUF3574 PF12098.8 AAZ37988.1 - 0.2 11.5 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3574) HTH_37 PF13744.6 AAZ37989.1 - 2.5e-27 94.6 0.4 2.8e-27 94.5 0.4 1.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 AAZ37989.1 - 0.00064 20.0 0.0 0.00085 19.6 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Coatomer_g_Cpla PF16381.5 AAZ37989.1 - 0.019 15.1 0.5 0.025 14.7 0.1 1.4 2 0 0 2 2 2 0 Coatomer subunit gamma-1 C-terminal appendage platform HTH_3 PF01381.22 AAZ37989.1 - 0.028 14.5 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix CsrA PF02599.16 AAZ37990.2 - 3.2e-13 49.4 3.0 4.9e-13 48.8 3.0 1.4 1 0 0 1 1 1 1 Global regulator protein family HopW1-1 PF15457.6 AAZ37991.1 - 1.9e-32 112.8 3.5 2.2e-32 112.6 3.5 1.0 1 0 0 1 1 1 1 Type III T3SS secreted effector HopW1-1/HopPmaA Exo70 PF03081.15 AAZ37991.1 - 0.0045 16.1 0.0 0.0049 16.0 0.0 1.0 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Glyco_hydro_125 PF06824.11 AAZ37991.1 - 0.11 11.4 0.0 0.11 11.4 0.0 1.0 1 0 0 1 1 1 0 Metal-independent alpha-mannosidase (GH125) Peptidase_C58 PF03543.14 AAZ37992.2 - 1.2e-13 51.3 0.7 2.7e-10 40.3 0.0 2.1 2 0 0 2 2 2 2 Yersinia/Haemophilus virulence surface antigen DUF2092 PF09865.9 AAZ37992.2 - 0.042 13.2 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2092) DUF1488 PF07369.11 AAZ37992.2 - 0.056 13.4 0.6 0.11 12.5 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1488) MCPsignal PF00015.21 AAZ37993.1 - 1.3e-42 145.5 25.2 1.3e-42 145.5 25.2 3.7 3 1 1 4 4 4 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AAZ37993.1 - 8.5e-06 26.1 0.0 8.5e-06 26.1 0.0 3.7 4 0 0 4 4 4 1 HAMP domain Cdc6_C PF09079.11 AAZ37993.1 - 0.05 13.6 0.1 1.8 8.6 0.0 2.9 2 1 1 3 3 3 0 CDC6, C terminal winged helix domain MRP-L47 PF06984.13 AAZ37993.1 - 0.1 12.7 2.4 0.33 11.1 0.7 2.5 2 0 0 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Rhabdo_ncap_2 PF03216.13 AAZ37993.1 - 0.11 12.0 1.0 0.13 11.7 0.1 1.7 2 0 0 2 2 2 0 Rhabdovirus nucleoprotein UPF0242 PF06785.11 AAZ37993.1 - 0.23 11.5 7.2 4.6 7.3 0.3 3.3 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus CheZ PF04344.13 AAZ37993.1 - 0.71 9.8 22.6 0.086 12.7 5.8 3.5 2 1 0 3 3 3 0 Chemotaxis phosphatase, CheZ AIP3 PF03915.13 AAZ37993.1 - 1 8.4 18.3 0.6 9.1 6.4 2.9 1 1 2 3 3 3 0 Actin interacting protein 3 NBP1 PF08537.10 AAZ37993.1 - 1.1 8.6 4.2 1.6 8.1 1.0 2.3 2 0 0 2 2 2 0 Fungal Nap binding protein NBP1 TipAS PF07739.13 AAZ37993.1 - 1.1 9.8 8.7 0.68 10.5 0.2 3.3 3 1 0 3 3 3 0 TipAS antibiotic-recognition domain DUF86 PF01934.17 AAZ37993.1 - 1.9 8.4 5.0 1.5 8.7 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function DUF86 Fib_alpha PF08702.10 AAZ37993.1 - 6.9 6.8 23.3 0.084 13.1 1.4 3.9 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family Peptidase_C58 PF03543.14 AAZ37994.1 - 3.5e-47 160.8 0.1 6.3e-47 159.9 0.1 1.4 1 0 0 1 1 1 1 Yersinia/Haemophilus virulence surface antigen PIN PF01850.21 AAZ37995.1 - 8.2e-17 61.8 0.1 9.2e-17 61.7 0.1 1.0 1 0 0 1 1 1 1 PIN domain DUF4411 PF14367.6 AAZ37995.1 - 0.00035 20.5 0.0 0.00077 19.4 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4411) PIN_3 PF13470.6 AAZ37996.1 - 3.1e-18 66.6 0.1 4e-18 66.3 0.1 1.1 1 0 0 1 1 1 1 PIN domain PIN PF01850.21 AAZ37996.1 - 3.3e-09 37.3 0.3 9.3e-09 35.8 0.2 1.8 1 1 1 2 2 2 1 PIN domain PIN_2 PF10130.9 AAZ37996.1 - 0.0017 18.6 0.2 0.019 15.2 0.2 2.0 1 1 0 1 1 1 1 PIN domain PIN_9 PF18477.1 AAZ37996.1 - 0.045 14.1 0.1 0.077 13.3 0.1 1.5 1 1 0 1 1 1 0 PIN like domain DSBA PF01323.20 AAZ37996.1 - 0.063 13.0 0.0 0.078 12.7 0.0 1.1 1 0 0 1 1 1 0 DSBA-like thioredoxin domain PhdYeFM_antitox PF02604.19 AAZ37997.1 - 7.5e-06 25.7 0.6 0.00016 21.4 0.2 2.6 1 1 1 2 2 2 1 Antitoxin Phd_YefM, type II toxin-antitoxin system VapB_antitoxin PF09957.9 AAZ37998.1 - 1.7e-06 27.8 1.1 2.2e-06 27.5 1.1 1.2 1 0 0 1 1 1 1 Bacterial antitoxin of type II TA system, VapB Nucleo_LEF-12 PF06256.11 AAZ37998.1 - 0.085 12.6 0.0 0.085 12.6 0.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus LEF-12 protein ATP-grasp_4 PF13535.6 AAZ37999.1 - 0.00081 19.0 0.2 0.001 18.7 0.2 1.2 1 0 0 1 1 1 1 ATP-grasp domain DUF3813 PF12758.7 AAZ37999.1 - 0.048 14.0 0.9 0.075 13.4 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3813) Aminotran_3 PF00202.21 AAZ38000.1 - 3e-82 276.5 0.0 3.4e-82 276.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 AAZ38000.1 - 0.0053 16.1 0.0 0.01 15.1 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 AAZ38000.1 - 0.0054 16.0 0.0 0.015 14.5 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II 2OG-FeII_Oxy_3 PF13640.6 AAZ38002.1 - 3.5e-05 24.6 0.2 6e-05 23.9 0.2 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 AAZ38002.1 - 4.6e-05 24.0 0.0 7.6e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 AAZ38002.1 - 0.067 13.7 0.1 0.17 12.4 0.1 1.8 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF4096 PF13340.6 AAZ38004.1 - 5.9e-25 87.3 0.4 1.5e-24 86.0 0.4 1.7 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1 PF01609.21 AAZ38004.1 - 3.2e-14 53.1 0.0 5.7e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AAZ38004.1 - 6.8e-10 39.2 0.2 2.1e-09 37.6 0.2 1.9 1 0 0 1 1 1 1 Transposase DDE domain TarH PF02203.15 AAZ38005.1 - 0.17 11.8 4.3 18 5.2 0.0 3.7 3 0 0 3 3 3 0 Tar ligand binding domain homologue Snapin_Pallidin PF14712.6 AAZ38005.1 - 0.22 12.0 1.2 0.57 10.6 0.1 2.2 2 0 0 2 2 2 0 Snapin/Pallidin CagX PF03524.15 AAZ38006.1 - 1.2e-26 93.8 0.0 1.3e-26 93.6 0.0 1.0 1 0 0 1 1 1 1 Conjugal transfer protein Resolvase PF00239.21 AAZ38009.1 - 4.9e-22 78.6 2.7 1.3e-21 77.2 2.7 1.6 1 1 0 1 1 1 1 Resolvase, N terminal domain HTH_7 PF02796.15 AAZ38009.1 - 2.7e-05 24.2 0.0 6.8e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_28 PF13518.6 AAZ38009.1 - 0.0012 18.9 0.1 0.0034 17.5 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 AAZ38009.1 - 0.038 13.4 0.0 0.069 12.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Sigma70_r4_2 PF08281.12 AAZ38009.1 - 0.048 13.3 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 LacI PF00356.21 AAZ38009.1 - 0.074 12.9 0.2 0.23 11.3 0.2 1.9 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family TnsD PF15978.5 AAZ38009.1 - 0.075 12.0 0.1 0.11 11.5 0.1 1.2 1 0 0 1 1 1 0 Tn7-like transposition protein D Ribonuc_red_lgN PF00317.21 AAZ38009.1 - 0.091 12.8 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Ribonucleotide reductase, all-alpha domain His_Phos_1 PF00300.22 AAZ38010.1 - 8.9e-34 116.9 0.0 1.1e-33 116.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_31 PF13614.6 AAZ38011.1 - 6.3e-12 45.8 0.0 2.3e-07 30.9 0.0 2.2 1 1 1 2 2 2 2 AAA domain CbiA PF01656.23 AAZ38011.1 - 7.3e-10 39.0 0.0 9.8e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 AAZ38011.1 - 2.3e-09 36.9 0.0 6.7e-07 28.8 0.0 2.2 1 1 0 1 1 1 1 ATPase MipZ ParA PF10609.9 AAZ38011.1 - 1.9e-07 30.8 0.1 2.6e-06 27.1 0.1 2.0 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 AAZ38011.1 - 1.8e-05 24.4 0.1 0.011 15.2 0.3 2.3 2 0 0 2 2 2 2 Cellulose biosynthesis protein BcsQ ArsA_ATPase PF02374.15 AAZ38011.1 - 0.00044 19.5 0.0 0.00075 18.8 0.0 1.4 1 0 0 1 1 1 1 Anion-transporting ATPase Fer4_NifH PF00142.18 AAZ38011.1 - 0.0042 16.6 0.0 0.0075 15.7 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_33 PF13671.6 AAZ38011.1 - 0.048 13.8 0.1 0.079 13.1 0.1 1.4 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 AAZ38011.1 - 0.08 12.2 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin APS_kinase PF01583.20 AAZ38011.1 - 0.081 12.8 0.2 0.25 11.2 0.1 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase VirC1 PF07015.11 AAZ38011.1 - 0.09 12.1 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 VirC1 protein CLP1_P PF16575.5 AAZ38011.1 - 0.13 12.1 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_10 PF12846.7 AAZ38011.1 - 0.25 10.2 0.0 0.35 9.7 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Resolvase PF00239.21 AAZ38012.1 - 1e-05 25.7 0.0 1.2e-05 25.4 0.0 1.1 1 0 0 1 1 1 1 Resolvase, N terminal domain DDE_Tnp_Tn3 PF01526.17 AAZ38013.1 - 1.9e-81 273.8 0.0 2.2e-81 273.6 0.0 1.0 1 0 0 1 1 1 1 Tn3 transposase DDE domain DUF1460 PF07313.12 AAZ38013.1 - 0.097 12.0 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) ParG PF09274.10 AAZ38015.1 - 4.6e-05 23.5 0.0 5.5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 ParG ParD PF09386.10 AAZ38015.1 - 0.0013 19.1 0.0 0.002 18.5 0.0 1.3 1 0 0 1 1 1 1 Antitoxin ParD Usher PF00577.20 AAZ38018.1 - 2.3e-159 531.8 2.3 2.8e-159 531.5 2.3 1.1 1 0 0 1 1 1 1 Outer membrane usher protein PapC_N PF13954.6 AAZ38018.1 - 2.4e-36 125.0 0.0 4e-36 124.2 0.0 1.4 1 0 0 1 1 1 1 PapC N-terminal domain PapC_C PF13953.6 AAZ38018.1 - 6.6e-16 57.9 0.0 2e-15 56.4 0.0 1.9 1 0 0 1 1 1 1 PapC C-terminal domain HTH_Tnp_1 PF01527.20 AAZ38019.1 - 3.4e-16 59.3 0.9 4e-16 59.1 0.9 1.1 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 AAZ38019.1 - 8.3e-07 28.6 0.4 1.5e-06 27.8 0.0 1.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 AAZ38019.1 - 1.3e-06 27.7 0.0 2.1e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.6 AAZ38019.1 - 7.3e-06 26.0 0.0 1.3e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 AAZ38019.1 - 4.7e-05 23.8 0.2 0.00021 21.7 0.0 1.8 1 1 0 2 2 2 1 leucine-zipper of insertion element IS481 HTH_17 PF12728.7 AAZ38019.1 - 0.00082 19.5 0.0 0.0017 18.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Terminase_5 PF06056.12 AAZ38019.1 - 0.0012 18.7 0.1 0.0019 18.0 0.1 1.4 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) HTH_29 PF13551.6 AAZ38019.1 - 0.0058 16.6 0.0 0.0072 16.3 0.0 1.4 1 1 0 1 1 1 1 Winged helix-turn helix Phage_CI_repr PF07022.13 AAZ38019.1 - 0.011 15.9 0.0 0.016 15.3 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain Ada3 PF10198.9 AAZ38019.1 - 0.015 15.5 2.1 0.017 15.2 2.0 1.3 1 1 0 1 1 1 0 Histone acetyltransferases subunit 3 MerR PF00376.23 AAZ38019.1 - 0.016 14.9 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 MerR family regulatory protein HTH_22 PF13309.6 AAZ38019.1 - 0.03 14.4 0.4 0.066 13.3 0.0 1.9 2 1 0 2 2 2 0 HTH domain MerR_1 PF13411.6 AAZ38019.1 - 0.033 14.3 0.1 0.067 13.3 0.1 1.7 2 1 0 2 2 1 0 MerR HTH family regulatory protein TEX13 PF15186.6 AAZ38019.1 - 0.037 13.7 0.4 0.041 13.6 0.4 1.2 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family HTH_3 PF01381.22 AAZ38019.1 - 0.038 14.1 0.1 0.1 12.7 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix CENP-H PF05837.12 AAZ38019.1 - 0.048 14.1 0.5 0.053 13.9 0.5 1.0 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Gon7 PF08738.10 AAZ38019.1 - 0.056 13.5 0.1 0.063 13.4 0.1 1.2 1 0 0 1 1 1 0 Gon7 family TetR_N PF00440.23 AAZ38019.1 - 0.14 12.0 0.4 0.32 10.8 0.0 1.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family zf-CCCH_6 PF18585.1 AAZ38019.1 - 0.15 11.9 0.1 0.32 10.9 0.1 1.5 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 DUF4140 PF13600.6 AAZ38019.1 - 0.4 11.2 3.4 0.5 10.8 3.4 1.3 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) AAA_18 PF13238.6 AAZ38020.1 - 1.2e-13 51.8 0.0 1.5e-13 51.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain 6PF2K PF01591.18 AAZ38020.1 - 0.0047 16.3 0.2 0.023 14.0 0.0 1.9 2 0 0 2 2 2 1 6-phosphofructo-2-kinase KTI12 PF08433.10 AAZ38020.1 - 0.011 15.2 0.0 0.014 14.9 0.0 1.4 1 1 0 1 1 1 0 Chromatin associated protein KTI12 AAA_33 PF13671.6 AAZ38020.1 - 0.023 14.9 0.0 0.039 14.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 AAZ38020.1 - 0.027 14.9 0.1 0.18 12.2 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.6 AAZ38020.1 - 0.044 14.2 0.0 0.21 12.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain ATP_bind_2 PF03668.15 AAZ38020.1 - 0.062 12.6 0.0 0.073 12.4 0.0 1.1 1 0 0 1 1 1 0 P-loop ATPase protein family RuvB_N PF05496.12 AAZ38020.1 - 0.092 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 AAZ38020.1 - 0.19 12.2 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) rve PF00665.26 AAZ38021.1 - 4e-34 117.4 0.1 7.4e-34 116.5 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 AAZ38021.1 - 6.8e-12 45.8 0.0 1e-11 45.3 0.0 1.2 1 0 0 1 1 1 1 DDE domain rve_3 PF13683.6 AAZ38021.1 - 8.8e-11 41.4 0.8 8.8e-11 41.4 0.8 1.8 2 0 0 2 2 2 1 Integrase core domain HTH_21 PF13276.6 AAZ38021.1 - 6.4e-10 39.0 1.4 1.6e-09 37.8 0.1 2.2 2 0 0 2 2 2 1 HTH-like domain rve_2 PF13333.6 AAZ38021.1 - 0.002 18.2 0.0 0.004 17.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain FtsK_gamma PF09397.10 AAZ38021.1 - 0.068 13.0 0.1 0.36 10.7 0.1 2.2 2 0 0 2 2 2 0 Ftsk gamma domain ParE_toxin PF05016.15 AAZ38022.1 - 2.2e-17 63.5 0.6 2.4e-17 63.3 0.6 1.0 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE HTH_Tnp_1 PF01527.20 AAZ38023.1 - 8.7e-09 35.6 2.8 3.5e-08 33.7 2.8 1.8 1 1 0 1 1 1 1 Transposase HTH_28 PF13518.6 AAZ38023.1 - 0.011 15.8 0.1 0.017 15.3 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain MerR_1 PF13411.6 AAZ38023.1 - 0.049 13.7 0.0 0.12 12.5 0.0 1.8 1 1 0 1 1 1 0 MerR HTH family regulatory protein TSC22 PF01166.18 AAZ38023.1 - 0.072 13.4 0.3 0.2 12.0 0.4 1.6 2 0 0 2 2 2 0 TSC-22/dip/bun family IpaC_SipC PF09599.10 AAZ38023.1 - 0.09 12.3 0.0 0.11 12.0 0.0 1.0 1 0 0 1 1 1 0 Salmonella-Shigella invasin protein C (IpaC_SipC) PemK_toxin PF02452.17 AAZ38024.1 - 3.8e-20 72.3 0.1 5.1e-20 71.9 0.1 1.3 1 1 0 1 1 1 1 PemK-like, MazF-like toxin of type II toxin-antitoxin system Transposase_mut PF00872.18 AAZ38025.1 - 1.6e-30 106.2 0.0 2e-30 105.9 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family rve PF00665.26 AAZ38027.1 - 5.6e-34 116.9 0.1 1e-33 116.1 0.1 1.4 1 0 0 1 1 1 1 Integrase core domain HTH_21 PF13276.6 AAZ38027.1 - 3.4e-14 52.7 2.3 8e-14 51.5 2.3 1.6 1 0 0 1 1 1 1 HTH-like domain rve_2 PF13333.6 AAZ38027.1 - 4e-12 46.1 1.7 8.3e-12 45.1 1.7 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 AAZ38027.1 - 7e-09 35.3 0.2 1.5e-08 34.3 0.2 1.6 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 AAZ38027.1 - 3.1e-07 30.7 0.5 4e-07 30.3 0.5 1.1 1 0 0 1 1 1 1 DDE domain Adeno_E1B_19K PF01691.16 AAZ38027.1 - 0.077 12.5 0.1 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 Adenovirus E1B 19K protein / small t-antigen Relaxase PF03432.14 AAZ38028.1 - 0.063 12.9 0.0 0.064 12.9 0.0 1.0 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain LIAS_N PF16881.5 AAZ38028.1 - 0.12 12.9 0.0 0.14 12.6 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain of lipoyl synthase of Radical_SAM family Glyco_hydro_28 PF00295.17 AAZ38029.1 - 8.1e-50 169.7 1.9 1.1e-49 169.2 1.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 ComK PF06338.11 AAZ38032.1 - 0.1 12.2 0.0 0.11 12.1 0.0 1.0 1 0 0 1 1 1 0 ComK protein DDE_Tnp_1 PF01609.21 AAZ38033.1 - 5.4e-23 81.8 0.7 7.2e-23 81.3 0.7 1.1 1 0 0 1 1 1 1 Transposase DDE domain DUF772 PF05598.11 AAZ38033.1 - 1.6e-19 69.7 0.0 2.8e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Transposase domain (DUF772) DDE_Tnp_1_3 PF13612.6 AAZ38033.1 - 1.3e-05 25.2 0.1 2e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 Transposase DDE domain CsrA PF02599.16 AAZ38034.2 - 3.2e-13 49.4 3.0 4.9e-13 48.8 3.0 1.4 1 0 0 1 1 1 1 Global regulator protein family ParE_toxin PF05016.15 AAZ38036.1 - 5.6e-11 42.9 0.0 6.6e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE DUF4350 PF14258.6 AAZ38036.1 - 0.094 13.2 0.1 0.65 10.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) HTH_Tnp_1 PF01527.20 AAZ38037.1 - 1e-15 57.8 0.3 1.2e-15 57.5 0.3 1.2 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 AAZ38037.1 - 6.5e-06 25.8 0.0 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 AAZ38037.1 - 8.6e-06 25.1 0.0 1.1e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.6 AAZ38037.1 - 1.2e-05 25.4 0.0 2.2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 AAZ38037.1 - 0.0069 16.9 0.0 0.011 16.2 0.0 1.3 1 1 0 1 1 1 1 leucine-zipper of insertion element IS481 HTH_17 PF12728.7 AAZ38037.1 - 0.0087 16.2 0.1 0.015 15.5 0.1 1.6 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_22 PF13309.6 AAZ38037.1 - 0.019 15.1 0.0 0.065 13.3 0.0 1.9 1 1 0 1 1 1 0 HTH domain HTH_7 PF02796.15 AAZ38037.1 - 0.025 14.6 0.0 0.045 13.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Terminase_5 PF06056.12 AAZ38037.1 - 0.042 13.7 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) Sigma70_r4_2 PF08281.12 AAZ38037.1 - 0.074 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_29 PF13551.6 AAZ38037.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix MerR PF00376.23 AAZ38037.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 MerR family regulatory protein Cadherin_2 PF08266.12 AAZ38037.1 - 0.14 12.0 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Cadherin-like CENP-B_N PF04218.13 AAZ38037.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain GRDP-like PF07173.12 AAZ38038.1 - 0.0096 16.6 1.9 0.013 16.1 1.4 1.4 1 1 0 1 1 1 1 Glycine-rich domain-containing protein-like Resolvase PF00239.21 AAZ38039.1 - 4.2e-28 98.3 0.1 4.5e-28 98.2 0.1 1.0 1 0 0 1 1 1 1 Resolvase, N terminal domain DUF1090 PF06476.12 AAZ38042.1 - 0.0039 17.3 0.4 0.0039 17.3 0.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1090) KxDL PF10241.9 AAZ38042.1 - 0.053 13.8 0.6 0.053 13.8 0.6 2.3 2 1 0 2 2 2 0 Uncharacterized conserved protein TraF_2 PF13729.6 AAZ38042.1 - 0.056 12.8 0.3 0.092 12.1 0.3 1.3 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein ATG16 PF08614.11 AAZ38042.1 - 1.9 8.7 14.8 1.7 8.9 5.1 2.8 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) FMN_bind_2 PF04299.12 AAZ38043.1 - 0.036 13.8 0.0 0.04 13.6 0.0 1.0 1 0 0 1 1 1 0 Putative FMN-binding domain Phage_integrase PF00589.22 AAZ38044.1 - 1.4e-26 93.3 0.1 2.2e-26 92.6 0.1 1.2 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 AAZ38044.1 - 2.6e-10 40.5 1.1 7.1e-10 39.1 1.1 1.7 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 AAZ38044.1 - 1.2e-07 32.1 0.0 2.1e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Smr PF01713.21 AAZ38044.1 - 0.26 11.7 2.5 2.7 8.4 0.5 2.7 3 0 0 3 3 3 0 Smr domain Resolvase PF00239.21 AAZ38045.1 - 2.1e-22 79.8 4.1 5.4e-22 78.5 4.1 1.6 1 1 0 1 1 1 1 Resolvase, N terminal domain HTH_7 PF02796.15 AAZ38045.1 - 2.4e-08 33.9 0.0 5.8e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_28 PF13518.6 AAZ38045.1 - 0.0017 18.4 0.1 0.0057 16.8 0.1 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 AAZ38045.1 - 0.0078 15.6 0.1 0.016 14.6 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 Sigma70_r4_2 PF08281.12 AAZ38045.1 - 0.05 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 TnsD PF15978.5 AAZ38045.1 - 0.052 12.5 0.0 0.073 12.1 0.0 1.2 1 0 0 1 1 1 0 Tn7-like transposition protein D LacI PF00356.21 AAZ38045.1 - 0.058 13.2 0.2 0.15 11.9 0.2 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family HTH_35 PF13693.6 AAZ38045.1 - 0.071 13.2 0.2 0.87 9.7 0.1 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding rve PF00665.26 AAZ38046.1 - 1.5e-26 92.9 0.0 2.9e-26 92.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain HTH_21 PF13276.6 AAZ38046.1 - 2.8e-18 65.8 0.4 1.1e-16 60.7 1.5 2.4 2 0 0 2 2 2 1 HTH-like domain rve_3 PF13683.6 AAZ38046.1 - 4.6e-10 39.1 0.0 8.9e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_2 PF13333.6 AAZ38046.1 - 0.0022 18.1 0.0 0.0039 17.3 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain EAL PF00563.20 AAZ38047.1 - 5.6e-65 219.2 0.0 8.3e-65 218.6 0.0 1.3 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AAZ38047.1 - 1.6e-36 125.4 0.0 4e-36 124.2 0.0 1.6 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Holin_BlyA PF05102.12 AAZ38047.1 - 0.047 13.6 0.1 0.15 12.0 0.1 1.9 1 0 0 1 1 1 0 holin, BlyA family Arc PF03869.14 AAZ38048.1 - 7.5e-05 22.5 0.3 0.0001 22.1 0.3 1.2 1 0 0 1 1 1 1 Arc-like DNA binding domain DUF4096 PF13340.6 AAZ38049.1 - 5.8e-25 87.3 0.4 1.5e-24 86.0 0.4 1.8 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1 PF01609.21 AAZ38049.1 - 3.2e-14 53.1 0.0 5.7e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AAZ38049.1 - 7.2e-10 39.1 0.2 2.1e-09 37.6 0.2 1.9 1 0 0 1 1 1 1 Transposase DDE domain HTH_Tnp_Tc3_2 PF01498.18 AAZ38049.1 - 0.061 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Transposase CagE_TrbE_VirB PF03135.14 AAZ38050.1 - 3.3e-19 69.8 0.0 5.4e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system CbiA PF01656.23 AAZ38050.1 - 0.0053 16.8 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_10 PF12846.7 AAZ38050.1 - 0.019 13.9 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Glyco_hydro_68 PF02435.16 AAZ38051.1 - 2.6e-171 570.2 0.0 3e-171 570.0 0.0 1.0 1 0 0 1 1 1 1 Levansucrase/Invertase Glyco_hydro_43 PF04616.14 AAZ38051.1 - 0.001 18.4 0.1 0.011 15.0 0.1 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 AfaD PF05775.12 AAZ38052.1 - 4.9e-21 75.2 0.6 5.9e-21 74.9 0.6 1.1 1 0 0 1 1 1 1 Enterobacteria AfaD invasin protein TPR_2 PF07719.17 AAZ38053.2 - 0.14 12.4 0.3 2.2 8.6 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Transposase_20 PF02371.16 AAZ38055.1 - 6.1e-25 87.4 2.1 1.3e-24 86.3 2.1 1.6 1 1 0 1 1 1 1 Transposase IS116/IS110/IS902 family TetR_N PF00440.23 AAZ38055.1 - 0.14 12.0 0.2 2 8.3 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family DUF4158 PF13700.6 AAZ38057.1 - 4.6e-10 39.6 0.2 4.8e-10 39.5 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4158) RHH_6 PF16762.5 AAZ38059.1 - 6.9e-38 129.1 0.6 7.7e-38 129.0 0.6 1.0 1 0 0 1 1 1 1 Ribbon-helix-helix domain DUF2944 PF11161.8 AAZ38061.1 - 0.012 15.5 21.9 22 4.8 0.0 9.4 10 0 0 10 10 10 0 Protein of unknown function (DUF2946) Fz PF01392.22 AAZ38061.1 - 0.042 14.5 2.6 8.2 7.1 0.2 3.2 2 0 0 2 2 2 0 Fz domain TPR_16 PF13432.6 AAZ38061.1 - 0.25 12.0 40.4 5.4 7.7 0.2 10.7 8 3 2 10 10 10 0 Tetratricopeptide repeat T3SS_needle_F PF09392.10 AAZ38061.1 - 0.44 10.8 5.1 21 5.4 0.1 4.7 3 0 0 3 3 3 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF VirC1 PF07015.11 AAZ38062.1 - 6.8e-17 61.5 0.0 9.5e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 VirC1 protein AAA_31 PF13614.6 AAZ38062.1 - 1.1e-10 41.7 0.3 7.8e-07 29.2 0.1 2.2 1 1 1 2 2 2 2 AAA domain CbiA PF01656.23 AAZ38062.1 - 1.5e-10 41.3 0.0 1.9e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 AAZ38062.1 - 2.7e-05 23.6 0.8 0.27 10.5 0.0 2.7 2 1 0 3 3 3 2 ATPase MipZ ArsA_ATPase PF02374.15 AAZ38062.1 - 5.7e-05 22.4 0.2 8.5e-05 21.9 0.2 1.3 1 0 0 1 1 1 1 Anion-transporting ATPase ParA PF10609.9 AAZ38062.1 - 0.0014 18.1 0.0 0.0025 17.3 0.0 1.4 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 AAZ38062.1 - 0.093 12.2 0.0 1.6 8.1 0.0 2.5 3 0 0 3 3 3 0 Cellulose biosynthesis protein BcsQ Zeta_toxin PF06414.12 AAZ38062.1 - 0.13 11.5 0.1 0.28 10.4 0.1 1.6 2 0 0 2 2 2 0 Zeta toxin LSDAT_euk PF18139.1 AAZ38062.1 - 0.26 10.6 1.1 0.53 9.6 0.2 1.7 1 1 0 2 2 2 0 SLOG in TRPM ParE_toxin PF05016.15 AAZ38063.1 - 2.2e-17 63.5 0.6 2.4e-17 63.3 0.6 1.0 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE HopW1-1 PF15457.6 AAZ38064.1 - 1.9e-32 112.8 3.5 2.2e-32 112.6 3.5 1.0 1 0 0 1 1 1 1 Type III T3SS secreted effector HopW1-1/HopPmaA Exo70 PF03081.15 AAZ38064.1 - 0.0045 16.1 0.0 0.0049 16.0 0.0 1.0 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Glyco_hydro_125 PF06824.11 AAZ38064.1 - 0.11 11.4 0.0 0.11 11.4 0.0 1.0 1 0 0 1 1 1 0 Metal-independent alpha-mannosidase (GH125) HrpJ PF07201.11 AAZ38065.1 - 0.0096 16.3 1.3 0.05 13.9 0.3 2.0 1 1 1 2 2 2 2 HrpJ-like domain Replicase PF03090.17 AAZ38066.1 - 9.6e-46 154.9 0.1 1.4e-45 154.3 0.1 1.3 1 0 0 1 1 1 1 Replicase family PriCT_1 PF08708.11 AAZ38066.1 - 7e-20 70.5 0.1 1.5e-19 69.5 0.1 1.5 1 0 0 1 1 1 1 Primase C terminal 1 (PriCT-1) LacI PF00356.21 AAZ38066.1 - 4.5 7.1 6.9 4 7.3 4.0 2.4 2 1 0 2 2 2 0 Bacterial regulatory proteins, lacI family SIR2_2 PF13289.6 AAZ38067.1 - 7.1e-24 84.6 0.5 1.3e-23 83.7 0.5 1.5 1 0 0 1 1 1 1 SIR2-like domain AAA_22 PF13401.6 AAZ38067.1 - 1.6e-06 28.4 0.5 0.0034 17.7 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_14 PF13173.6 AAZ38067.1 - 5.1e-06 26.6 0.0 1.1e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAZ38067.1 - 0.0019 18.6 0.0 0.0052 17.2 0.0 1.7 2 0 0 2 2 1 1 AAA ATPase domain AAA PF00004.29 AAZ38067.1 - 0.003 18.0 0.3 0.021 15.3 0.2 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 AAZ38067.1 - 0.016 14.9 0.0 0.063 13.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 AAZ38067.1 - 0.016 15.1 0.2 0.1 12.5 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.6 AAZ38067.1 - 0.025 14.8 0.0 0.05 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 AAZ38067.1 - 0.034 14.2 0.0 0.075 13.1 0.0 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_7 PF12775.7 AAZ38067.1 - 0.04 13.4 0.0 0.078 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ResIII PF04851.15 AAZ38067.1 - 0.042 13.9 0.2 4 7.4 0.0 3.0 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit ATPase_2 PF01637.18 AAZ38067.1 - 0.045 13.6 0.1 0.23 11.3 0.0 2.1 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 AAZ38067.1 - 0.057 12.6 0.0 0.094 11.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.15 AAZ38067.1 - 0.087 12.7 0.0 0.26 11.2 0.0 1.8 2 0 0 2 2 2 0 NTPase AAA_31 PF13614.6 AAZ38068.1 - 2.9e-19 69.7 1.3 1.6e-12 47.7 0.1 2.2 1 1 1 2 2 2 2 AAA domain CbiA PF01656.23 AAZ38068.1 - 7.9e-15 55.0 0.0 2.9e-14 53.2 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 AAZ38068.1 - 1.8e-06 27.5 1.1 4.2e-05 23.0 0.1 2.7 1 1 2 3 3 3 1 ATPase MipZ ParA PF10609.9 AAZ38068.1 - 2.4e-06 27.2 1.4 1.4e-05 24.7 0.1 2.3 3 0 0 3 3 3 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 AAZ38068.1 - 5.1e-05 22.9 0.1 8.8e-05 22.1 0.1 1.4 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ VirC1 PF07015.11 AAZ38068.1 - 0.0012 18.2 0.1 0.005 16.2 0.1 1.8 1 1 0 1 1 1 1 VirC1 protein ArsA_ATPase PF02374.15 AAZ38068.1 - 0.0043 16.3 0.4 0.0076 15.5 0.1 1.6 2 0 0 2 2 2 1 Anion-transporting ATPase Toprim_3 PF13362.6 AAZ38068.1 - 0.017 15.5 0.4 7.5 7.0 0.0 3.1 3 1 0 3 3 3 0 Toprim domain Fer4_NifH PF00142.18 AAZ38068.1 - 0.026 14.0 0.0 0.065 12.7 0.0 1.7 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_24 PF13479.6 AAZ38068.1 - 0.055 13.2 0.0 0.086 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 AAZ38068.1 - 0.093 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein KTI12 PF08433.10 AAZ38068.1 - 0.23 10.9 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 RelB PF04221.12 AAZ38070.1 - 6e-25 87.0 0.1 7.3e-25 86.8 0.1 1.1 1 0 0 1 1 1 1 RelB antitoxin MobC PF05713.11 AAZ38071.1 - 7.8e-05 23.1 0.8 0.00013 22.4 0.8 1.5 1 0 0 1 1 1 1 Bacterial mobilisation protein (MobC) HTH_48 PF17906.1 AAZ38071.1 - 0.011 15.9 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 0 HTH domain in Mos1 transposase 23S_rRNA_IVP PF05635.11 AAZ38071.1 - 0.062 13.6 0.1 0.086 13.1 0.1 1.2 1 0 0 1 1 1 0 23S rRNA-intervening sequence protein IMS PF00817.20 AAZ38072.1 - 2e-31 109.0 0.0 3.6e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family DUF4113 PF13438.6 AAZ38072.1 - 7.7e-18 64.3 0.5 1.4e-17 63.4 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4113) IMS_C PF11799.8 AAZ38072.1 - 3.8e-11 43.7 0.0 1e-10 42.4 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 AAZ38072.1 - 0.00045 20.4 0.0 0.0014 18.8 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif CagE_TrbE_VirB PF03135.14 AAZ38073.1 - 2.3e-20 73.6 0.0 4e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system CbiA PF01656.23 AAZ38073.1 - 0.029 14.4 0.0 0.054 13.6 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain HATPase_c_3 PF13589.6 AAZ38074.1 - 7e-07 29.2 0.0 1.4e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YoeB_toxin PF06769.14 AAZ38076.1 - 5e-36 122.6 0.1 6.3e-36 122.3 0.1 1.1 1 0 0 1 1 1 1 YoeB-like toxin of bacterial type II toxin-antitoxin system HigB-like_toxin PF05015.13 AAZ38076.1 - 5.5e-05 23.5 0.1 0.00077 19.8 0.0 2.0 1 1 0 2 2 2 1 RelE-like toxin of type II toxin-antitoxin system HigB ParE-like_toxin PF15781.5 AAZ38076.1 - 0.0051 16.7 0.0 0.0089 16.0 0.0 1.4 2 0 0 2 2 2 1 ParE-like toxin of type II bacterial toxin-antitoxin system Gp49 PF05973.14 AAZ38077.1 - 2.3e-06 27.7 0.0 3e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Phage derived protein Gp49-like (DUF891) ParE_toxin PF05016.15 AAZ38077.1 - 0.014 16.0 0.0 0.021 15.4 0.0 1.2 1 0 0 1 1 1 0 ParE toxin of type II toxin-antitoxin system, parDE AP2 PF00847.20 AAZ38077.1 - 0.15 12.3 0.8 1.9 8.7 0.0 2.3 2 0 0 2 2 2 0 AP2 domain GntR PF00392.21 AAZ38080.1 - 8.2e-19 67.0 0.2 1.1e-18 66.6 0.2 1.2 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_24 PF13412.6 AAZ38080.1 - 0.0011 18.4 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 AAZ38080.1 - 0.0023 17.9 0.1 0.039 13.9 0.0 2.0 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain TrmB PF01978.19 AAZ38080.1 - 0.0027 17.5 0.0 0.032 14.1 0.0 2.0 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 AAZ38080.1 - 0.0031 17.4 0.0 0.0052 16.7 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_11 PF08279.12 AAZ38080.1 - 0.0055 16.6 0.0 0.009 15.9 0.0 1.4 1 0 0 1 1 1 1 HTH domain MarR PF01047.22 AAZ38080.1 - 0.012 15.5 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_DeoR PF08220.12 AAZ38080.1 - 0.014 15.1 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_36 PF13730.6 AAZ38080.1 - 0.034 14.1 0.0 0.05 13.6 0.0 1.5 1 1 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 AAZ38080.1 - 0.042 13.4 0.1 0.44 10.1 0.0 2.2 1 1 1 2 2 2 0 Sigma-70, region 4 Rrf2 PF02082.20 AAZ38080.1 - 0.054 13.8 0.0 0.11 12.8 0.0 1.5 1 1 0 1 1 1 0 Transcriptional regulator RPA_C PF08784.11 AAZ38080.1 - 0.08 13.6 0.0 0.59 10.8 0.0 2.0 1 1 1 2 2 2 0 Replication protein A C terminal Fe_dep_repress PF01325.19 AAZ38080.1 - 0.12 12.6 0.0 0.24 11.6 0.0 1.7 2 1 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain HTH_10 PF04967.12 AAZ38080.1 - 0.23 11.3 1.4 0.46 10.3 0.0 2.2 2 1 1 3 3 3 0 HTH DNA binding domain SRAP PF02586.14 AAZ38081.1 - 9.5e-35 120.1 0.0 1.1e-34 119.9 0.0 1.0 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) rve PF00665.26 AAZ38082.1 - 5.3e-11 42.8 0.0 1.9e-10 41.0 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain HTH_29 PF13551.6 AAZ38082.1 - 0.00017 21.6 0.1 0.03 14.3 0.0 2.9 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.6 AAZ38082.1 - 0.00026 20.7 0.3 0.019 14.7 0.0 2.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.15 AAZ38082.1 - 0.0013 18.8 0.9 0.0088 16.1 0.1 2.6 2 1 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_28 PF13518.6 AAZ38082.1 - 0.0044 17.1 0.7 0.021 14.9 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.6 AAZ38082.1 - 0.011 16.4 3.0 0.32 11.6 0.1 3.4 3 0 0 3 3 3 0 Homeodomain-like domain HTH_17 PF12728.7 AAZ38082.1 - 0.017 15.3 0.0 0.077 13.2 0.0 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_DeoR PF08220.12 AAZ38082.1 - 0.023 14.4 0.0 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain HTH_IclR PF09339.10 AAZ38082.1 - 0.037 13.8 0.2 0.94 9.3 0.0 2.6 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 AAZ38082.1 - 0.041 13.3 0.3 0.12 11.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_36 PF13730.6 AAZ38082.1 - 0.052 13.5 0.0 0.53 10.3 0.0 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_11 PF08279.12 AAZ38082.1 - 0.068 13.1 0.1 0.43 10.6 0.0 2.4 3 0 0 3 3 3 0 HTH domain GntR PF00392.21 AAZ38082.1 - 0.12 12.0 0.0 0.47 10.1 0.0 2.0 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family TetR_N PF00440.23 AAZ38082.1 - 0.23 11.3 1.5 0.59 10.0 0.5 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family HTH_22 PF13309.6 AAZ38082.1 - 0.42 10.7 2.1 1.1 9.4 0.3 2.6 2 0 0 2 2 2 0 HTH domain CbiA PF01656.23 AAZ38083.1 - 1.5e-07 31.5 0.0 2.3e-07 30.9 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 AAZ38083.1 - 4.3e-05 23.1 0.0 6.5e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase IstB_IS21 PF01695.17 AAZ38083.1 - 0.0034 17.2 0.0 0.0053 16.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein ArsA_ATPase PF02374.15 AAZ38083.1 - 0.011 15.0 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase CLP1_P PF16575.5 AAZ38083.1 - 0.015 15.1 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_31 PF13614.6 AAZ38083.1 - 0.018 15.0 0.0 0.039 13.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain Torsin PF06309.11 AAZ38083.1 - 0.048 13.8 0.0 0.14 12.3 0.0 1.8 2 0 0 2 2 2 0 Torsin AAA_16 PF13191.6 AAZ38083.1 - 0.097 13.0 0.0 0.14 12.6 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain T4SS PF07996.11 AAZ38084.1 - 3.5e-24 86.3 18.7 6e-24 85.5 18.7 1.4 1 1 0 1 1 1 1 Type IV secretion system proteins DUF3450 PF11932.8 AAZ38084.1 - 2 7.6 21.4 1.6 8.0 17.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) FCD PF07729.12 AAZ38085.1 - 3.4e-25 88.9 1.8 5.5e-25 88.2 1.8 1.3 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 AAZ38085.1 - 1.6e-20 72.5 0.1 2.8e-20 71.7 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_11 PF08279.12 AAZ38085.1 - 8e-06 25.7 0.1 3e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 HTH domain HTH_41 PF14502.6 AAZ38085.1 - 0.00016 21.3 0.0 0.00036 20.2 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 AAZ38085.1 - 0.00025 21.0 0.0 0.00053 19.9 0.0 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Rrf2 PF02082.20 AAZ38085.1 - 0.0018 18.6 0.0 0.0043 17.4 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulator HTH_24 PF13412.6 AAZ38085.1 - 0.0032 17.0 0.1 0.0086 15.6 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding PaaX PF07848.12 AAZ38085.1 - 0.0038 17.4 0.1 0.0087 16.3 0.1 1.6 1 0 0 1 1 1 1 PaaX-like protein Fe_dep_repress PF01325.19 AAZ38085.1 - 0.024 14.8 0.0 0.32 11.2 0.0 2.5 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain HTH_CodY PF08222.11 AAZ38085.1 - 0.032 13.8 0.0 0.077 12.6 0.0 1.6 1 0 0 1 1 1 0 CodY helix-turn-helix domain HTH_46 PF15977.5 AAZ38085.1 - 0.046 13.7 0.0 0.16 12.0 0.0 1.9 1 0 0 1 1 1 0 Winged helix-turn-helix DNA binding HTH_DeoR PF08220.12 AAZ38085.1 - 0.047 13.4 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain EAP30 PF04157.16 AAZ38085.1 - 0.048 12.9 0.1 0.14 11.5 0.0 1.7 2 0 0 2 2 2 0 EAP30/Vps36 family MarR_2 PF12802.7 AAZ38085.1 - 0.12 12.3 0.0 0.34 10.8 0.0 1.7 1 0 0 1 1 1 0 MarR family TrbI PF03743.14 AAZ38086.1 - 2.7e-38 131.7 0.3 2.7e-38 131.7 0.3 1.9 3 0 0 3 3 3 1 Bacterial conjugation TrbI-like protein Gram_pos_anchor PF00746.21 AAZ38086.1 - 0.013 15.4 0.4 0.029 14.3 0.4 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif DUF4307 PF14155.6 AAZ38086.1 - 0.1 12.4 1.5 3.3 7.6 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) DUF4366 PF14283.6 AAZ38086.1 - 0.27 11.3 2.7 0.47 10.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) DUF3619 PF12279.8 AAZ38086.1 - 4.8 7.5 8.1 3.9 7.8 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3619) TrbL PF04610.14 AAZ38087.1 - 1.1e-36 126.7 31.5 1.1e-36 126.7 31.5 1.7 1 1 1 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein YafQ_toxin PF15738.5 AAZ38089.1 - 2.1e-33 114.5 0.1 2.5e-33 114.3 0.1 1.0 1 0 0 1 1 1 1 Bacterial toxin of type II toxin-antitoxin system, YafQ ParE_toxin PF05016.15 AAZ38089.1 - 9.6e-10 39.0 0.2 1.1e-09 38.8 0.2 1.0 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE T2SSE PF00437.20 AAZ38090.1 - 1.1e-31 109.9 0.0 1.3e-31 109.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein Mg_chelatase PF01078.21 AAZ38090.1 - 5e-05 22.8 0.1 0.0001 21.8 0.0 1.6 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 AAZ38090.1 - 0.0073 16.7 0.0 0.014 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Pox_A32 PF04665.12 AAZ38090.1 - 0.0076 15.7 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Poxvirus A32 protein FtsK_SpoIIIE PF01580.18 AAZ38090.1 - 0.016 14.6 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.6 AAZ38090.1 - 0.018 14.7 0.1 0.34 10.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 AAZ38090.1 - 0.023 14.9 0.0 0.14 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 AAZ38090.1 - 0.028 13.9 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 AAZ38090.1 - 0.031 14.5 0.0 0.06 13.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 AAZ38090.1 - 0.033 14.0 0.0 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 AAZ38090.1 - 0.065 13.0 0.0 0.22 11.3 0.1 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_18 PF13238.6 AAZ38090.1 - 0.075 13.6 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 AAZ38090.1 - 0.09 12.5 0.1 0.35 10.6 0.2 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein AAA PF00004.29 AAZ38090.1 - 0.15 12.5 0.0 0.27 11.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 AAZ38090.1 - 0.17 11.6 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase PhdYeFM_antitox PF02604.19 AAZ38091.1 - 1.1e-18 66.8 0.0 1.3e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 Antitoxin Phd_YefM, type II toxin-antitoxin system PHD_like PF12910.7 AAZ38091.1 - 0.00046 20.2 0.0 0.00051 20.1 0.0 1.2 1 1 0 1 1 1 1 Antitoxin of toxin-antitoxin, RelE / RelB, TA system Replicase PF03090.17 AAZ38092.1 - 3.9e-46 156.2 0.1 5.9e-46 155.6 0.1 1.3 1 0 0 1 1 1 1 Replicase family PriCT_1 PF08708.11 AAZ38092.1 - 8e-20 70.4 0.1 1.6e-19 69.3 0.1 1.5 1 0 0 1 1 1 1 Primase C terminal 1 (PriCT-1) LacI PF00356.21 AAZ38092.1 - 9.8 6.1 7.7 1.6 8.5 2.0 2.4 2 1 1 3 3 3 0 Bacterial regulatory proteins, lacI family LPD7 PF18821.1 AAZ38093.1 - 3e-15 56.1 1.2 1.3e-14 54.1 0.3 2.5 2 0 0 2 2 2 1 Large polyvalent protein-associated domain 7 T4SS-DNA_transf PF02534.14 AAZ38094.1 - 1.2e-77 261.8 0.0 5.6e-77 259.5 0.0 1.8 2 0 0 2 2 2 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 AAZ38094.1 - 1.8e-26 92.6 0.0 3e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 AAZ38094.1 - 2.7e-18 66.0 0.0 1.9e-16 60.0 0.0 2.2 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain MFS_1 PF07690.16 AAZ38095.1 - 1.1e-26 93.6 43.6 2e-16 59.8 18.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AAZ38095.1 - 1.6e-24 86.6 22.2 4.6e-24 85.1 9.0 2.1 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 AAZ38095.1 - 0.00016 20.4 28.3 0.00051 18.7 12.8 2.4 1 1 0 1 1 1 1 MFS/sugar transport protein MFS_4 PF06779.14 AAZ38095.1 - 0.51 9.6 28.5 14 4.9 28.5 2.4 1 1 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB Phage_integrase PF00589.22 AAZ38096.1 - 2.6e-27 95.7 0.1 3.9e-27 95.1 0.1 1.2 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 AAZ38096.1 - 7.3e-11 42.2 3.2 8e-11 42.1 1.2 2.1 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 AAZ38096.1 - 2.5e-07 31.1 0.0 5.2e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Smr PF01713.21 AAZ38096.1 - 0.018 15.4 1.2 0.31 11.4 0.2 2.7 3 0 0 3 3 3 0 Smr domain HTH_3 PF01381.22 AAZ38099.1 - 4e-07 30.0 0.1 1.4e-06 28.3 0.0 1.8 1 1 1 2 2 2 1 Helix-turn-helix TetR_N PF00440.23 AAZ38099.1 - 4.8e-05 23.1 0.3 0.00054 19.7 0.0 2.4 1 1 1 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_26 PF13443.6 AAZ38099.1 - 6.2e-05 23.3 0.0 9.4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_7 PF02796.15 AAZ38099.1 - 0.0068 16.5 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_18 PF12833.7 AAZ38099.1 - 0.019 15.2 0.0 0.03 14.6 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_31 PF13560.6 AAZ38099.1 - 0.051 13.9 0.0 0.082 13.3 0.0 1.3 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_28 PF13518.6 AAZ38099.1 - 0.18 12.0 0.1 0.34 11.1 0.1 1.6 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 AAZ38099.1 - 0.21 11.6 1.0 0.35 10.9 0.2 1.8 2 0 0 2 2 2 0 Winged helix-turn helix Glyco_hydro_43 PF04616.14 AAZ38100.1 - 0.023 14.0 0.0 0.073 12.4 0.0 1.6 1 1 1 2 2 2 0 Glycosyl hydrolases family 43 F5_F8_type_C PF00754.25 AAZ38100.1 - 0.098 12.8 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 F5/8 type C domain AAA_22 PF13401.6 AAZ38101.1 - 1.9e-11 44.4 0.1 4.7e-11 43.1 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAZ38101.1 - 3.1e-06 27.7 2.0 1.8e-05 25.2 0.3 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 AAZ38101.1 - 0.00015 22.2 0.0 0.00031 21.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 AAZ38101.1 - 0.00038 20.2 0.0 0.00073 19.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 AAZ38101.1 - 0.0041 17.1 0.1 0.0079 16.2 0.1 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE PIF1 PF05970.14 AAZ38101.1 - 0.0056 15.9 0.0 0.0097 15.1 0.0 1.4 1 0 0 1 1 1 1 PIF1-like helicase ABC_tran PF00005.27 AAZ38101.1 - 0.0086 16.6 0.0 0.014 15.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_19 PF13245.6 AAZ38101.1 - 0.025 14.9 0.3 0.1 13.0 0.3 1.9 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AAZ38101.1 - 0.028 14.6 0.0 0.047 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 AAZ38101.1 - 0.031 14.3 0.4 0.69 9.9 0.4 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 AAZ38101.1 - 0.039 14.5 0.1 0.099 13.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 AAZ38101.1 - 0.06 12.4 0.2 0.11 11.6 0.2 1.6 1 1 0 1 1 1 0 Type II/IV secretion system protein KTI12 PF08433.10 AAZ38101.1 - 0.068 12.6 0.1 0.1 12.0 0.1 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ATPase_2 PF01637.18 AAZ38101.1 - 0.068 13.1 0.1 0.32 10.9 0.1 2.0 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 AAZ38101.1 - 0.092 12.1 0.2 0.29 10.5 0.2 1.9 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 AAZ38101.1 - 0.1 12.0 0.2 0.27 10.5 0.1 1.5 1 1 0 1 1 1 0 KaiC PRK PF00485.18 AAZ38101.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_7 PF12775.7 AAZ38101.1 - 0.11 12.1 0.1 0.18 11.3 0.1 1.4 1 1 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 AAZ38101.1 - 0.12 12.3 0.2 0.29 11.0 0.2 1.8 1 1 0 1 1 1 0 NACHT domain cobW PF02492.19 AAZ38101.1 - 0.12 11.9 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain HTH_3 PF01381.22 AAZ38102.1 - 3.2e-11 43.1 0.0 5.5e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 AAZ38102.1 - 1.1e-08 35.3 0.0 2e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 AAZ38102.1 - 7.1e-05 22.7 0.0 0.0001 22.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 AAZ38102.1 - 0.0052 17.2 0.0 0.016 15.7 0.0 1.8 2 0 0 2 2 2 1 Cro/C1-type HTH DNA-binding domain DUF5338 PF17273.2 AAZ38103.1 - 0.0042 17.1 0.0 0.0073 16.4 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5338) DUF4006 PF13179.6 AAZ38104.1 - 0.12 12.3 1.5 0.14 12.1 0.2 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF4006) DUF413 PF04219.12 AAZ38104.1 - 0.17 12.0 0.1 0.2 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF TrbM PF07424.11 AAZ38105.1 - 5.4e-08 32.9 0.0 7.6e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 TrbM DAO PF01266.24 AAZ38106.1 - 7.8e-63 213.2 0.0 9.5e-63 212.9 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 AAZ38106.1 - 5.6e-05 22.5 0.2 0.053 12.8 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 AAZ38106.1 - 0.00021 20.0 0.1 0.86 8.1 0.0 2.8 2 1 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) HI0933_like PF03486.14 AAZ38106.1 - 0.0014 17.4 0.7 0.54 8.9 0.2 2.4 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.6 AAZ38106.1 - 0.0018 18.5 0.6 0.004 17.3 0.6 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 AAZ38106.1 - 0.06 12.4 0.3 0.096 11.7 0.3 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 AAZ38106.1 - 0.12 11.6 0.5 5.5 6.1 0.6 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AAZ38106.1 - 0.14 11.3 0.3 0.26 10.5 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 AAZ38106.1 - 0.15 10.9 0.4 0.2 10.5 0.4 1.1 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.6 AAZ38106.1 - 0.18 11.8 0.4 0.78 9.7 0.1 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 AAZ38106.1 - 0.26 10.3 1.3 0.47 9.5 1.3 1.4 1 0 0 1 1 1 0 FAD binding domain VirB8 PF04335.13 AAZ38107.1 - 5.4e-30 104.8 0.3 6.9e-30 104.5 0.3 1.1 1 0 0 1 1 1 1 VirB8 protein PI3K_P85_iSH2 PF16454.5 AAZ38107.1 - 0.017 14.7 0.2 0.028 14.0 0.2 1.4 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Big_1 PF02369.16 AAZ38107.1 - 0.16 12.0 1.0 1.3 9.1 0.3 2.3 1 1 1 2 2 2 0 Bacterial Ig-like domain (group 1) Topoisom_bac PF01131.20 AAZ38108.1 - 2.7e-87 293.5 0.0 3.3e-87 293.2 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim_Crpt PF13342.6 AAZ38108.1 - 1.2e-18 66.8 0.6 2.3e-18 65.9 0.6 1.5 1 0 0 1 1 1 1 C-terminal repeat of topoisomerase Toprim PF01751.22 AAZ38108.1 - 5.3e-14 52.3 0.0 1.5e-13 50.8 0.0 1.8 1 0 0 1 1 1 1 Toprim domain OrfB_Zn_ribbon PF07282.11 AAZ38108.1 - 0.22 11.5 0.3 0.46 10.5 0.3 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Prok-RING_1 PF14446.6 AAZ38108.1 - 0.26 11.2 0.5 0.47 10.4 0.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Peptidase_S24 PF00717.23 AAZ38109.1 - 1.8e-12 47.0 0.0 2.5e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase S24-like RHH_1 PF01402.21 AAZ38111.1 - 9e-05 22.3 0.5 0.00019 21.2 0.1 1.6 2 0 0 2 2 2 1 Ribbon-helix-helix protein, copG family CagX PF03524.15 AAZ38112.1 - 6.8e-41 140.3 0.0 8.9e-41 139.9 0.0 1.1 1 0 0 1 1 1 1 Conjugal transfer protein SSB PF00436.25 AAZ38113.1 - 1.1e-36 125.0 0.3 1.5e-36 124.5 0.3 1.2 1 0 0 1 1 1 1 Single-strand binding protein family Pex14_N PF04695.13 AAZ38113.1 - 0.27 11.9 6.2 0.5 11.0 6.2 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Transposase_mut PF00872.18 AAZ38115.1 - 2.8e-117 391.8 0.0 3.4e-117 391.5 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAZ38115.1 - 7.7e-05 23.0 0.0 0.00021 21.6 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain DUF4844 PF16133.5 AAZ38115.1 - 0.23 12.0 0.0 0.55 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) zinc_ribbon_4 PF13717.6 AAZ38117.1 - 0.0024 17.8 0.9 1.6 8.7 0.1 2.3 2 0 0 2 2 2 2 zinc-ribbon domain FdhE PF04216.12 AAZ38117.1 - 0.074 12.9 0.4 0.088 12.7 0.4 1.1 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation Cys_rich_CPXG PF14255.6 AAZ38117.1 - 0.079 12.9 1.1 3.3 7.7 0.1 2.2 2 0 0 2 2 2 0 Cysteine-rich CPXCG Elf1 PF05129.13 AAZ38117.1 - 0.1 12.7 0.1 0.14 12.3 0.1 1.2 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like CpXC PF14353.6 AAZ38117.1 - 0.1 12.6 0.9 0.98 9.5 0.1 2.1 1 1 0 2 2 2 0 CpXC protein Auto_anti-p27 PF06677.12 AAZ38117.1 - 0.2 11.9 0.2 0.2 11.9 0.2 1.8 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Zn_Tnp_IS1595 PF12760.7 AAZ38117.1 - 0.53 10.3 4.3 2.1 8.4 4.3 1.8 1 1 0 1 1 1 0 Transposase zinc-ribbon domain TrbC PF04956.13 AAZ38118.1 - 0.0039 17.4 4.6 0.0054 16.9 3.1 1.8 1 1 1 2 2 2 2 TrbC/VIRB2 family AAA_31 PF13614.6 AAZ38120.1 - 9.3e-17 61.5 3.0 1.4e-10 41.3 1.2 2.2 1 1 1 2 2 2 2 AAA domain MipZ PF09140.11 AAZ38120.1 - 1e-12 47.9 3.1 7.4e-11 41.8 3.1 2.1 1 1 0 1 1 1 1 ATPase MipZ CbiA PF01656.23 AAZ38120.1 - 1.8e-08 34.5 0.0 2.5e-08 34.0 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 AAZ38120.1 - 3.6e-05 23.3 0.7 5.3e-05 22.8 0.7 1.2 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase ArsA_ATPase PF02374.15 AAZ38120.1 - 0.00086 18.6 0.4 0.0012 18.1 0.4 1.2 1 0 0 1 1 1 1 Anion-transporting ATPase Fer4_NifH PF00142.18 AAZ38120.1 - 0.003 17.1 0.1 0.0047 16.4 0.1 1.2 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 AAZ38120.1 - 0.19 11.4 0.5 0.33 10.6 0.5 1.4 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain NusG PF02357.19 AAZ38123.1 - 5.6e-11 42.8 0.0 8.1e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Transcription termination factor nusG VirB3 PF05101.13 AAZ38124.1 - 7.7e-06 26.0 6.7 1.3e-05 25.3 6.7 1.3 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein Peptidase_U4 PF03419.13 AAZ38124.1 - 0.16 11.3 1.2 0.19 11.0 1.2 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Tropomyosin PF00261.20 AAZ38125.1 - 0.0085 15.5 1.5 0.02 14.3 1.3 1.6 1 1 0 1 1 1 1 Tropomyosin Activator-TraM PF11657.8 AAZ38125.1 - 0.076 12.9 1.5 0.15 11.9 1.4 1.5 1 1 0 1 1 1 0 Transcriptional activator TraM DUF1929 PF09118.11 AAZ38126.1 - 0.02 15.2 0.0 0.046 14.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1929) SLT PF01464.20 AAZ38127.1 - 1.1e-12 47.6 0.0 1.5e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Transglycosylase SLT domain Resolvase PF00239.21 AAZ38128.1 - 8.9e-45 152.4 1.5 1.4e-44 151.7 1.5 1.3 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_7 PF02796.15 AAZ38128.1 - 3.7e-09 36.5 0.1 7.9e-09 35.5 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 AAZ38128.1 - 2.6e-05 23.9 0.1 7e-05 22.5 0.1 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 AAZ38128.1 - 5.1e-05 23.2 7.5 0.00036 20.5 0.1 2.8 3 0 0 3 3 3 1 Winged helix-turn helix HTH_22 PF13309.6 AAZ38128.1 - 0.00049 20.1 0.1 0.0038 17.3 0.0 2.2 2 0 0 2 2 2 1 HTH domain HTH_28 PF13518.6 AAZ38128.1 - 0.00055 20.0 0.0 0.00055 20.0 0.0 2.3 3 0 0 3 3 2 1 Helix-turn-helix domain HTH_38 PF13936.6 AAZ38128.1 - 0.0013 18.5 1.6 0.057 13.2 0.1 2.9 2 1 1 3 3 3 1 Helix-turn-helix domain HTH_17 PF12728.7 AAZ38128.1 - 0.0015 18.6 1.0 0.0046 17.1 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.6 AAZ38128.1 - 0.0019 18.8 0.8 0.0048 17.5 0.8 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_1_2 PF13022.6 AAZ38128.1 - 0.0043 17.2 0.0 0.0073 16.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix of insertion element transposase HTH_Tnp_1 PF01527.20 AAZ38128.1 - 0.0059 16.9 0.3 0.013 15.8 0.0 1.7 2 0 0 2 2 1 1 Transposase Sigma70_r4_2 PF08281.12 AAZ38128.1 - 0.01 15.5 0.1 0.027 14.1 0.1 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_8 PF02954.19 AAZ38128.1 - 0.013 15.2 0.9 0.28 11.0 0.0 3.0 3 0 0 3 3 2 0 Bacterial regulatory protein, Fis family HTH_10 PF04967.12 AAZ38128.1 - 0.015 15.1 0.0 0.046 13.5 0.0 1.8 1 0 0 1 1 1 0 HTH DNA binding domain Terminase_5 PF06056.12 AAZ38128.1 - 0.016 15.0 0.1 0.034 14.0 0.1 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) FUSC PF04632.12 AAZ38128.1 - 0.02 13.5 4.0 0.025 13.1 4.0 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Sigma54_CBD PF04963.13 AAZ38128.1 - 0.036 13.9 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain Sigma70_r4 PF04545.16 AAZ38128.1 - 0.038 13.5 0.1 0.18 11.4 0.0 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_40 PF14493.6 AAZ38128.1 - 0.044 14.3 0.1 0.11 12.9 0.1 1.7 1 1 0 1 1 1 0 Helix-turn-helix domain DUF134 PF02001.16 AAZ38128.1 - 0.054 14.1 0.0 0.098 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF134 Phage_AlpA PF05930.12 AAZ38128.1 - 0.066 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) CENP-B_N PF04218.13 AAZ38128.1 - 0.11 12.1 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Pseudomonas_syringae_pv._phaseolicola_1448A-ASM1220v1/GCA_000012205.1_ASM1220v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Pseudomonas_syringae_pv._phaseolicola_1448A-ASM1220v1/GCA_000012205.1_ASM1220v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Pseudomonas_syringae_pv._phaseolicola_1448A-ASM1220v1/GCA_000012205.1_ASM1220v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Pseudomonas_syringae_pv._phaseolicola_1448A-ASM1220v1/GCA_000012205.1_ASM1220v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 04:21:08 2019 # [ok]